A0A077Z5S1_TRITR Loading...

peptidylprolyl isomerase

AlphaFold DB , UniProt , Accession A0A077Z5S1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 633 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.4Very low31.7Very low240 Ų240170.7 Ų170.7100%1.18283%0.825SS**  0119.80-102.9171.3167.800105.9
2K32Very low32.1Very low205 Ų205167.6 Ų167.689%0.89181%0.808SS**  trans-52.4141.3-164.2-76.2179.6172.3-178.50113.3
3D33.9Very low32.4Very low143 Ų143166.7 Ų166.777%0.76580%0.802SS**  trans-52.2128.5-172.9-56.5-64.8000112.7D5D3-D5 VanDerWaalsContact C-N 3.33Å; D3-D5 PolarHBondContact O-N 3.07Å
4R30Very low33.2Very low213 Ų213157.4 Ų157.480%0.80476%0.762SS**  trans-89.576.1168-70.3-179.4-177177.11.5107.4R6R4-R6 PolarHBondContact O-N 2.95Å
5D34.9Very low34.2Very low147 Ų147148.5 Ų148.579%0.78673%0.728SS**  trans-72.989.4158.7-72.4-29.3000106.6D3 D7D3-D5 VanDerWaalsContact C-N 3.33Å; D3-D5 PolarHBondContact O-N 3.07Å; D5-D7 PolarHBondContact O-N 3.15Å
6R30.5Very low35.4Very low193 Ų193140.1 Ų140.173%0.72869%0.688SS**  trans-77.3108.2164.9-77.1-178-175.2-178.5-0.1106.2R4 E8R4-R6 PolarHBondContact O-N 2.95Å; R6-E8 PolarHBondContact O-N 2.94Å
7D32.3Very low36.3Very low147 Ų147136.6 Ų136.679%0.78667%0.672SS**  trans-51.9102.9162-70.5-53.8000108.6D5 D9D5-D7 PolarHBondContact O-N 3.15Å; D7-D9 VanDerWaalsContact C-N 3.29Å; D7-D9 PolarHBondContact O-N 2.99Å
8E29.1Very low36.8Very low182 Ų182134.1 Ų134.185%0.8566%0.662SS**  trans-84.36.2-179.3-92.4-170.5169.600114R6 G10R6-E8 PolarHBondContact O-N 2.94Å; E8-G10 PolarHBondContact O-N 2.88Å
9D32.3Very low37.5Very low140 Ų140128.9 Ų128.975%0.74964%0.64SS**  trans-95.678175.6-71.6-33.5000111D7 R11D7-D9 VanDerWaalsContact C-N 3.29Å; D7-D9 PolarHBondContact O-N 2.99Å; D9-R11 PolarHBondContact O-N 3.38Å
10G26.7Very low37.4Very low80 Ų80132.7 Ų132.783%0.82566%0.656SS**  trans-6632171.400000114.9E8 E12E8-G10 PolarHBondContact O-N 2.88Å; G10-E12 PolarHBondContact O-N 3.22Å; G10-E12 VanDerWaalsContact O-N 3.13Å
11R33.3Very low37.2Very low188 Ų188129.4 Ų129.471%0.70965%0.645SS**  trans-75.4100.6173.3-67.4-169.7-175.1-165.31.7108.1D9 E13 E36D9-R11 PolarHBondContact O-N 3.38Å; R11-E13 PolarHBondContact O-N 2.66Å; R11-E36 IonicContact NH1-OE1 2.62Å; R11-E36 PolarHBondContact NH1-OE1 3.38Å; R11-E36 IonicContact NH2-OE1 3.49Å
12E36.6Very low37.4Very low133 Ų133129.4 Ų129.462%0.62163%0.632SS**  trans-42.4120.4177.6-69.8-178.7152.500111.3G10 C14 N300G10-E12 PolarHBondContact O-N 3.22Å; G10-E12 VanDerWaalsContact O-N 3.13Å; E12-C14 VanDerWaalsContact C-N 3.26Å; E12-C14 PolarHBondContact O-N 3.37Å; E12-N300 PolarHBondContact OE1-ND2 2.8Å; E12-N300 PolarHBondContact OE2-ND2 3.32Å
13E35.8Very low37.4Very low156 Ų156129 Ų12973%0.72963%0.633SS**  trans-74.773.8-172.3-157171.3-146.200111.1R11 G15R11-E13 PolarHBondContact O-N 2.66Å; E13-G15 VanDerWaalsContact C-N 3.34Å; E13-G15 PolarHBondContact O-N 2.96Å
14C43.7Very low37.4Very low36 Ų36128.5 Ų128.524%0.24363%0.626CS.*  trans-86.866.2174.5-82.20000111.2E12 R298 C355E12-C14 VanDerWaalsContact C-N 3.26Å; E12-C14 PolarHBondContact O-N 3.37Å; C14-R298 PolarHBondContact SG-O 3.08Å; C14-R298 VanDerWaalsContact SG-O 3.39Å; C14-C355 WeakPolarHBondContact O-CB 3.3Å
15G47.7Very low37.6Very low24 Ų24123.4 Ų123.425%0.24762%0.621CS.*  trans-89.4139.2170.300000112.2E13 R298E13-G15 VanDerWaalsContact C-N 3.34Å; E13-G15 PolarHBondContact O-N 2.96Å; G15-R298 PolarHBondContact O-NH1 3.42Å
16P53.6Low37.9Very low14 Ų14123 Ų1239%0.09163%0.626CS.*  trans-59.3141.8165.822.5-29.8000110.7L18 I285 L348 N353P16-L18 PolarHBondContact O-N 3.08Å; P16-I285 HydrophobicContact CB-CB 4.47Å; P16-I285 HydrophobicContact CB-CD1 4.42Å; P16-I285 HydrophobicContact CB-CG1 4.29Å; P16-I285 HydrophobicContact CB-CG2 3.52Å; P16-I285 HydrophobicContact CG-CD1 3.95Å; P16-I285 HydrophobicContact CG-CG1 4.27Å; P16-I285 HydrophobicContact CG-CG2 4.17Å; P16-L348 HydrophobicContact CG-CD1 3.75Å; P16-N353 WeakPolarHBondContact CD-O 3.25Å
17L52Low38.5Very low81 Ų81116.8 Ų116.842%0.42461%0.612SS.*  trans-68.2115.3173.2-81.7151.2000108.4S19 N291L17-S19 PolarHBondContact O-N 3.24Å; L17-N291 VanDerWaalsContact CD1-OD1 3.25Å; L17-N291 WeakPolarHBondContact CD1-OD1 3.44Å
18L45.1Very low39.4Very low92 Ų92119.4 Ų119.448%0.48262%0.617SS.*BIsolated β-bridgetrans-66.6113.1166.3-63.6174.5000106.6P16 K283 I285 N353P16-L18 PolarHBondContact O-N 3.08Å; L18-K283 HydrophobicContact CD2-CB 4.28Å; L18-I285 HydrophobicContact CD2-CG1 4.23Å; L18-N353 HydrophobicContact CD2-CB 4.4Å
19S48.7Very low40.7Very low36 Ų36120.7 Ų120.725%0.25261%0.614SS.*  trans-72.5138.2173.662.40000109.2L17 C21 V284L17-S19 PolarHBondContact O-N 3.24Å; S19-C21 PolarHBondContact O-N 2.84Å; S19-V284 PolarHBondContact N-O 3.08Å; S19-V284 VanDerWaalsContact N-O 3.16Å; S19-V284 VanDerWaalsContact OG-CB 3.3Å; S19-V284 WeakPolarHBondContact OG-CB 3.49Å; S19-V284 WeakPolarHBondContact OG-CG1 3.4Å
20E36.7Very low42.7Very low203 Ų203120.1 Ų120.195%0.94960%0.601SS**SBendtrans-15.685.9179.6-63.4179.6-176.600114.8
21C33.4Very low45.3Very low64 Ų64119.5 Ų119.543%0.43259%0.588SS.*  trans-136.4126.8166-83.40000106.4S19 E23S19-C21 PolarHBondContact O-N 2.84Å; C21-E23 PolarHBondContact O-N 3.41Å
22R37Very low47.8Very low241 Ų241111.4 Ų111.491%0.90956%0.559SS**  trans-7.7106.8-176.1-66.7178.6178.7-175.5-0.9113.7E24R22-E24 PolarHBondContact O-N 2.89Å
23E32.1Very low50.2Low197 Ų197111.8 Ų111.892%0.92156%0.561SS**  trans-55.799168.7-67.8-175.7164.600108.9C21C21-E23 PolarHBondContact O-N 3.41Å
24E34.6Very low52.6Low132 Ų132108.3 Ų108.362%0.61754%0.543SS*.  trans-67.9140165.1-75.6-170.7160.300108.2R22 R30R22-E24 PolarHBondContact O-N 2.89Å; E24-R30 IonicContact OE2-CZ 3.25Å; E24-R30 IonicContact OE2-NH1 3.15Å; E24-R30 IonicContact OE2-NH2 3.62Å; E24-R30 PolarHBondContact OE2-NH2 2.94Å
25P34.2Very low54.8Low106 Ų106108.7 Ų108.769%0.68854%0.542SS*.  trans-56.9151-178.623.5-32.9000110.3S27P25-S27 PolarHBondContact O-N 3.5Å
26P39.5Very low56.8Low137 Ų137112.2 Ų112.289%0.8955%0.551SS**  trans-63.683.2-173.526-34.2000110.7
27S43.8Very low58.4Low64 Ų64112.4 Ų112.445%0.44855%0.552SS.*  trans-71136.7173.179.60000107.1P25 R29 R30P25-S27 PolarHBondContact O-N 3.5Å; S27-R29 PolarHBondContact O-N 3.4Å; S27-R29 VanDerWaalsContact O-N 3.17Å; S27-R30 PolarHBondContact OG-NE 2.81Å
28K51.7Low60.2Low202 Ų202110.7 Ų110.788%0.87854%0.54SS*.SBendtrans-21.8117.2171.2-71.4179175.5-178.80110.6R30K28-R30 PolarHBondContact O-N 2.86Å
29R56.5Low62.5Low208 Ų208106.7 Ų106.779%0.78552%0.519SS*.  trans-29.6105.3-177.1-82.5-179.6173.1172.1-1.2109.3S27 A31S27-R29 PolarHBondContact O-N 3.4Å; S27-R29 VanDerWaalsContact O-N 3.17Å; R29-A31 PolarHBondContact O-N 2.92Å
30R72.8Confident64.5Low129 Ų129110.1 Ų110.149%0.48753%0.526SS..  trans-61112.7179.9-66.2179.6-176.3173.72.9105.4E24 S27 K28 K351 T352E24-R30 IonicContact OE2-CZ 3.25Å; E24-R30 IonicContact OE2-NH1 3.15Å; E24-R30 IonicContact OE2-NH2 3.62Å; E24-R30 PolarHBondContact OE2-NH2 2.94Å; S27-R30 PolarHBondContact OG-NE 2.81Å; K28-R30 PolarHBondContact O-N 2.86Å; R30-K351 HydrophobicContact CB-CG 4.5Å; R30-T352 WeakPolarHBondContact O-CG2 3.36Å
31A82.1Confident67.1Low67 Ų67102.4 Ų102.455%0.55450%0.495SS*.  trans-104140.1173.300000108.2R29 K351R29-A31 PolarHBondContact O-N 2.92Å; A31-K351 VanDerWaalsContact O-CE 3.29Å; A31-K351 WeakPolarHBondContact O-CE 3.23Å; A31-K351 PolarHBondContact O-NZ 3.24Å
32L86.5Confident70.1Confident17 Ų1799.4 Ų99.49%0.08947%0.474CS..  trans-81.1115.7165.8179.863.5000107.3F34 E35 Y38 N335 F336 N349 K351L32-F34 PolarHBondContact O-N 2.81Å; L32-E35 HydrophobicContact CB-CB 4.17Å; L32-E35 HydrophobicContact CD2-CB 4.32Å; L32-E35 HydrophobicContact CD2-CG 4.31Å; L32-E35 HydrophobicContact CG-CB 4.36Å; L32-E35 PolarHBondContact O-N 3.27Å; L32-Y38 HydrophobicContact CD1-CE2 4.32Å; L32-Y38 HydrophobicContact CD2-CD2 4.02Å; L32-Y38 HydrophobicContact CD2-CE2 4.45Å; L32-Y38 HydrophobicContact CG-CD2 4.28Å; L32-Y38 HydrophobicContact CG-CE2 4.32Å; L32-N335 HydrophobicContact CD1-CB 4.46Å; L32-N335 WeakPolarHBondContact CD1-OD1 3.07Å; L32-N335 HydrophobicContact CD2-CB 3.69Å; L32-F336 HydrophobicContact CD2-CE1 4.49Å; L32-F336 HydrophobicContact CD2-CE2 4.26Å; L32-F336 HydrophobicContact CD2-CZ 3.87Å; L32-N349 WeakPolarHBondContact CB-ND2 3.42Å; L32-K351 HydrophobicContact CB-CD 4.26Å; L32-K351 HydrophobicContact CD1-CD 4.07Å
33E87Confident72.9Confident141 Ų14187.9 Ų87.966%0.65943%0.431SS*.THydrogen-bonded Turntrans-61136173.5-67.9175.6-176.100108.4E35 Y38E33-E35 VanDerWaalsContact C-N 3.26Å; E33-E35 PolarHBondContact O-N 2.77Å; E33-Y38 VanDerWaalsContact O-CE2 3.31Å; E33-Y38 WeakPolarHBondContact O-CE2 3.28Å
34F86.1Confident75.8Confident84 Ų8481.1 Ų81.137%0.36841%0.406SS..THydrogen-bonded Turntrans60.127-178.7-45.4-72.8000115.2L32 E36 I37 Y38 M395 A399L32-F34 PolarHBondContact O-N 2.81Å; F34-E36 VanDerWaalsContact C-N 3.26Å; F34-E36 PolarHBondContact O-N 3.26Å; F34-E36 VanDerWaalsContact O-N 3.16Å; F34-I37 HydrophobicContact CB-CB 4.29Å; F34-I37 HydrophobicContact CB-CD1 3.98Å; F34-I37 HydrophobicContact CB-CG1 4.22Å; F34-I37 HydrophobicContact CD1-CD1 3.93Å; F34-I37 HydrophobicContact CG-CD1 4.31Å; F34-I37 WeakPolarHBondContact O-CB 3.39Å; F34-I37 PolarHBondContact O-N 2.72Å; F34-Y38 HydrophobicContact CB-CE2 4.27Å; F34-Y38 VanDerWaalsContact O-CD2 3.29Å; F34-Y38 WeakPolarHBondContact O-CD2 3.48Å; F34-Y38 PolarHBondContact O-N 2.81Å; F34-M395 HydrophobicContact CD2-SD 4.4Å; F34-A399 HydrophobicContact CD1-CB 4.34Å; F34-A399 HydrophobicContact CE1-CB 4.32Å
35E90.3Very high78.6Confident44 Ų4475 Ų7521%0.20638%0.377CS..Hα-helixtrans-46.1-47.5179.4-175175.2111.300113.2L32 E33 I37 Y38 L39 F336 N349L32-E35 HydrophobicContact CB-CB 4.17Å; L32-E35 HydrophobicContact CD2-CB 4.32Å; L32-E35 HydrophobicContact CD2-CG 4.31Å; L32-E35 HydrophobicContact CG-CB 4.36Å; L32-E35 PolarHBondContact O-N 3.27Å; E33-E35 VanDerWaalsContact C-N 3.26Å; E33-E35 PolarHBondContact O-N 2.77Å; E35-I37 VanDerWaalsContact C-N 3.27Å; E35-I37 PolarHBondContact O-N 2.83Å; E35-Y38 PolarHBondContact O-N 2.94Å; E35-L39 HydrophobicContact CG-CD1 3.9Å; E35-L39 HydrophobicContact CG-CG 4.35Å; E35-L39 WeakPolarHBondContact O-CB 3.44Å; E35-L39 WeakPolarHBondContact O-CG 3.4Å; E35-L39 PolarHBondContact O-N 3.3Å; E35-F336 HydrophobicContact CG-CE1 4.35Å; E35-F336 HydrophobicContact CG-CZ 3.95Å; E35-N349 PolarHBondContact OE2-ND2 3.1Å
36E88.6Confident81.2Confident97 Ų9774.3 Ų74.345%0.45337%0.368SS..Hα-helixtrans-63.5-30.3-178.7-66.6-68.6173.700112.9R11 F34 R40R11-E36 IonicContact NH1-OE1 2.62Å; R11-E36 PolarHBondContact NH1-OE1 3.38Å; R11-E36 IonicContact NH2-OE1 3.49Å; F34-E36 VanDerWaalsContact C-N 3.26Å; F34-E36 PolarHBondContact O-N 3.26Å; F34-E36 VanDerWaalsContact O-N 3.16Å; E36-R40 WeakPolarHBondContact O-CG 3.15Å; E36-R40 PolarHBondContact O-N 3.41Å
37I87.3Confident83.7Confident19 Ų1968.2 Ų68.210%0.09733%0.329CS..Hα-helixtrans-70.6-49.6177.4-57.8-175.6000109.5F34 E35 L39 R40 E398 A399F34-I37 HydrophobicContact CB-CB 4.29Å; F34-I37 HydrophobicContact CB-CD1 3.98Å; F34-I37 HydrophobicContact CB-CG1 4.22Å; F34-I37 HydrophobicContact CD1-CD1 3.93Å; F34-I37 HydrophobicContact CG-CD1 4.31Å; F34-I37 WeakPolarHBondContact O-CB 3.39Å; F34-I37 PolarHBondContact O-N 2.72Å; E35-I37 VanDerWaalsContact C-N 3.27Å; E35-I37 PolarHBondContact O-N 2.83Å; I37-L39 VanDerWaalsContact C-N 3.26Å; I37-L39 PolarHBondContact O-N 3.4Å; I37-R40 VanDerWaalsContact O-CB 3.32Å; I37-R40 WeakPolarHBondContact O-CB 3.17Å; I37-R40 PolarHBondContact O-N 3.45Å; I37-R40 VanDerWaalsContact O-N 3.07Å; I37-E398 HydrophobicContact CG2-CG 4.37Å; I37-A399 HydrophobicContact CD1-CB 3.49Å; I37-A399 VanDerWaalsContact CD1-CB 3.49Å
38Y90.5Very high86.1Confident45 Ų4566 Ų6618%0.17631%0.31CS..Hα-helixtrans-61.7-37.2177.2-61.1-60.6000112.1L32 E33 F34 E35 R40 S41 T333 M395L32-Y38 HydrophobicContact CD1-CE2 4.32Å; L32-Y38 HydrophobicContact CD2-CD2 4.02Å; L32-Y38 HydrophobicContact CD2-CE2 4.45Å; L32-Y38 HydrophobicContact CG-CD2 4.28Å; L32-Y38 HydrophobicContact CG-CE2 4.32Å; E33-Y38 VanDerWaalsContact O-CE2 3.31Å; E33-Y38 WeakPolarHBondContact O-CE2 3.28Å; F34-Y38 HydrophobicContact CB-CE2 4.27Å; F34-Y38 VanDerWaalsContact O-CD2 3.29Å; F34-Y38 WeakPolarHBondContact O-CD2 3.48Å; F34-Y38 PolarHBondContact O-N 2.81Å; E35-Y38 PolarHBondContact O-N 2.94Å; Y38-R40 PolarHBondContact O-N 3.34Å; Y38-S41 PolarHBondContact O-N 3.05Å; Y38-T333 HydrophobicContact CD1-CG2 3.73Å; Y38-T333 HydrophobicContact CE1-CG2 3.92Å; Y38-M395 HydrophobicContact CE1-CE 4.39Å; Y38-M395 HydrophobicContact CE1-SD 3.56Å; Y38-M395 VanDerWaalsContact CE1-SD 3.56Å; Y38-M395 HydrophobicContact CE2-SD 4.27Å; Y38-M395 WeakPolarHBondContact OH-CE 3.44Å; Y38-M395 PolarHBondContact OH-SD 2.84Å
39L92.5Very high88.1Confident8 Ų858 Ų584%0.04228%0.276CS..G310 helixtrans-63.7-17.6176.5-84.4175.6000114E35 I37 S41 I42 F336 V356 R357E35-L39 HydrophobicContact CG-CD1 3.9Å; E35-L39 HydrophobicContact CG-CG 4.35Å; E35-L39 WeakPolarHBondContact O-CB 3.44Å; E35-L39 WeakPolarHBondContact O-CG 3.4Å; E35-L39 PolarHBondContact O-N 3.3Å; I37-L39 VanDerWaalsContact C-N 3.26Å; I37-L39 PolarHBondContact O-N 3.4Å; L39-S41 PolarHBondContact O-N 3.42Å; L39-I42 HydrophobicContact CD2-CD1 4.49Å; L39-I42 PolarHBondContact O-N 2.89Å; L39-I42 VanDerWaalsContact O-O 3.11Å; L39-F336 HydrophobicContact CD1-CZ 4.5Å; L39-F336 HydrophobicContact CD2-CD1 4.35Å; L39-F336 HydrophobicContact CD2-CE1 3.83Å; L39-F336 HydrophobicContact CD2-CE2 4.24Å; L39-F336 HydrophobicContact CD2-CZ 3.77Å; L39-F336 HydrophobicContact CG-CE1 4.12Å; L39-F336 HydrophobicContact CG-CE2 4.25Å; L39-F336 HydrophobicContact CG-CZ 3.66Å; L39-V356 HydrophobicContact CD2-CG2 3.75Å; L39-R357 PolarHBondContact O-NH1 2.77Å; L39-R357 VanDerWaalsContact O-NH1 3.15Å; L39-R357 PolarHBondContact O-NH2 3.28Å; L39-R357 VanDerWaalsContact O-NH2 3.07Å
40R91.3Very high89.8Confident108 Ų10851.1 Ų51.141%0.40825%0.252SS..G310 helixtrans-67.9-21172.2-62-179.7-179.1-180-0112.6E36 I37 Y38 I42 P410 P412E36-R40 WeakPolarHBondContact O-CG 3.15Å; E36-R40 PolarHBondContact O-N 3.41Å; I37-R40 VanDerWaalsContact O-CB 3.32Å; I37-R40 WeakPolarHBondContact O-CB 3.17Å; I37-R40 PolarHBondContact O-N 3.45Å; I37-R40 VanDerWaalsContact O-N 3.07Å; Y38-R40 PolarHBondContact O-N 3.34Å; R40-I42 VanDerWaalsContact C-N 3.29Å; R40-P410 HydrophobicContact CB-CG 3.56Å; R40-P410 WeakPolarHBondContact O-CG 3.07Å; R40-P412 WeakPolarHBondContact O-CG 3.27Å
41S92.3Very high90.8Very high41 Ų4145 Ų4529%0.28723%0.229SC..G310 helixtrans-86.95.4175.9-69.30000114Y38 L39 S375 P412Y38-S41 PolarHBondContact O-N 3.05Å; L39-S41 PolarHBondContact O-N 3.42Å; S41-S375 PolarHBondContact OG-OG 3.04Å; S41-P412 WeakPolarHBondContact O-CB 3.5Å
42I95.5Very high91.5Very high0 Ų042.9 Ų42.90%021%0.207CC..SBendtrans-120.9140.5175.5-58.2177.7000108.1L39 R40 D331 F336 I338 V347 R357 P412 I414L39-I42 HydrophobicContact CD2-CD1 4.49Å; L39-I42 PolarHBondContact O-N 2.89Å; L39-I42 VanDerWaalsContact O-O 3.11Å; R40-I42 VanDerWaalsContact C-N 3.29Å; I42-D331 HydrophobicContact CD1-CB 4.24Å; I42-F336 HydrophobicContact CD1-CB 3.7Å; I42-F336 HydrophobicContact CD1-CD2 3.67Å; I42-F336 HydrophobicContact CD1-CE2 4.46Å; I42-F336 HydrophobicContact CD1-CG 3.74Å; I42-I338 HydrophobicContact CD1-CD1 4.21Å; I42-I338 HydrophobicContact CG1-CD1 4.4Å; I42-I338 HydrophobicContact CG2-CD1 4.33Å; I42-V347 HydrophobicContact CD1-CG1 3.76Å; I42-V347 HydrophobicContact CG2-CG1 4.31Å; I42-V347 HydrophobicContact CG2-CG2 3.92Å; I42-R357 PolarHBondContact O-NH1 2.68Å; I42-P412 VanDerWaalsContact C-CB 3.45Å; I42-I414 HydrophobicContact CG2-CD1 4.41Å
43P95.8Very high91.8Very high0 Ų043.6 Ų43.60%021%0.211CC..  trans-57.8150.4177-26.536.4000113R357 L359 P412 I414 F427 T428P43-R357 VanDerWaalsContact C-NH1 3.31Å; P43-R357 PolarHBondContact O-NH1 3.28Å; P43-L359 HydrophobicContact CB-CD1 4.1Å; P43-L359 WeakPolarHBondContact O-CD2 3.46Å; P43-P412 HydrophobicContact CG-CB 4.18Å; P43-I414 HydrophobicContact CG-CB 4.16Å; P43-I414 HydrophobicContact CG-CD1 3.94Å; P43-I414 HydrophobicContact CG-CG1 3.81Å; P43-F427 HydrophobicContact CB-CB 4.2Å; P43-F427 HydrophobicContact CG-CB 4.45Å; P43-F427 VanDerWaalsContact CG-O 3.28Å; P43-F427 WeakPolarHBondContact CG-O 3.41Å; P43-T428 WeakPolarHBondContact CB-O 3.38Å
44S93.7Very high92.2Very high55 Ų5536.9 Ų36.939%0.38518%0.179SC..  trans-118.1-15.2-178.965.10000115T428 N429S44-T428 PolarHBondContact N-O 3.37Å; S44-N429 PolarHBondContact N-OD1 3.46Å; S44-N429 VanDerWaalsContact N-OD1 3.09Å; S44-N429 PolarHBondContact OG-OD1 3.32Å; S44-N429 VanDerWaalsContact OG-OD1 3.1Å
45A91.9Very high92.3Very high2 Ų239 Ų392%0.01719%0.185CC..  trans-63.6142.1-178.500000111.9L359 T428 S430 E431A45-L359 WeakPolarHBondContact O-CD2 3.49Å; A45-T428 WeakPolarHBondContact CB-O 3.46Å; A45-T428 PolarHBondContact N-O 3.43Å; A45-T428 VanDerWaalsContact N-O 3.08Å; A45-S430 WeakPolarHBondContact CB-O 3.43Å; A45-E431 HydrophobicContact CB-CG 4.44Å
46N89.9Confident92.4Very high93 Ų9339.3 Ų39.350%0.49719%0.188SC..SBendtrans-74.8-33.5180-64-70.3000111.8G360 E431N46-G360 WeakPolarHBondContact O-CA 3.38Å; N46-G360 PolarHBondContact O-N 3.2Å; N46-E431 WeakPolarHBondContact CB-OE1 3.32Å; N46-E431 PolarHBondContact N-OE1 3.07Å; N46-E431 PolarHBondContact N-OE2 2.68Å; N46-E431 PolarHBondContact ND2-OE1 3.42Å
47A92.5Very high92.7Very high8 Ų836.8 Ų36.87%0.06618%0.179CC..SBendtrans-108.3160.6178.600000110.9E363 E431 P432A47-E363 VanDerWaalsContact CB-OE1 3.26Å; A47-E363 WeakPolarHBondContact CB-OE1 3.46Å; A47-E431 WeakPolarHBondContact CB-OE2 3.5Å; A47-E431 PolarHBondContact N-OE2 2.73Å; A47-E431 VanDerWaalsContact N-OE2 3.08Å; A47-P432 HydrophobicContact CB-CG 3.86Å
48Y94.4Very high93.2Very high17 Ų1736 Ų367%0.06718%0.175CC..  trans-72.2140169.465.1-94.2000109.7E363 Y425 L426 R442 D443Y48-E363 HydrophobicContact CD1-CG 3.96Å; Y48-E363 VanDerWaalsContact CE1-CD 3.49Å; Y48-E363 HydrophobicContact CE1-CG 4.17Å; Y48-E363 VanDerWaalsContact CE1-OE2 3.25Å; Y48-E363 WeakPolarHBondContact CE1-OE2 3.38Å; Y48-Y425 AromaticContact CD1-CD1 3.66Å; Y48-Y425 HydrophobicContact CD1-CD1 3.66Å; Y48-Y425 HydrophobicContact CD1-CE1 4.32Å; Y48-Y425 HydrophobicContact CD1-CG 4.43Å; Y48-Y425 AromaticContact CD2-CD1 3.8Å; Y48-Y425 HydrophobicContact CD2-CD1 3.8Å; Y48-Y425 AromaticContact CE1-CD1 3.68Å; Y48-Y425 HydrophobicContact CE1-CD1 3.68Å; Y48-Y425 AromaticContact CE1-CE1 3.88Å; Y48-Y425 HydrophobicContact CE1-CE1 3.88Å; Y48-Y425 AromaticContact CE2-CD1 3.82Å; Y48-Y425 HydrophobicContact CE2-CD1 3.82Å; Y48-Y425 HydrophobicContact CE2-CE1 4.22Å; Y48-Y425 AromaticContact CG-CD1 3.74Å; Y48-Y425 HydrophobicContact CG-CD1 3.74Å; Y48-Y425 HydrophobicContact CG-CG 4.41Å; Y48-Y425 AromaticContact CZ-CD1 3.78Å; Y48-Y425 AromaticContact CZ-CE1 3.86Å; Y48-L426 CarbonylContact C-O 3.59Å; Y48-L426 WeakPolarHBondContact CA-O 3.4Å; Y48-L426 WeakPolarHBondContact CB-O 3.46Å; Y48-R442 HydrophobicContact CD2-CG 4.33Å; Y48-R442 HydrophobicContact CE2-CG 3.84Å; Y48-R442 VanDerWaalsContact CE2-CZ 3.44Å; Y48-R442 VanDerWaalsContact CG-NH2 3.34Å; Y48-R442 VanDerWaalsContact CZ-NH2 3.25Å; Y48-R442 PolarHBondContact O-NE 3.05Å; Y48-R442 PolarHBondContact O-NH2 3.13Å; Y48-D443 PolarHBondContact OH-OD1 2.85Å
49E91.9Very high93.4Very high35 Ų3533.9 Ų33.916%0.16417%0.167CC..SBendtrans-75-50.5-179-170.6-160.8141.300110.8L426 T428 R442E49-L426 PolarHBondContact N-O 3.49Å; E49-T428 WeakPolarHBondContact OE2-CB 3.41Å; E49-T428 WeakPolarHBondContact OE2-CG2 3.34Å; E49-T428 PolarHBondContact OE2-OG1 3.36Å; E49-R442 WeakPolarHBondContact O-CG 3.38Å
50K92.8Very high93.7Very high64 Ų6434.1 Ų34.128%0.27817%0.168SC..EExtended strand (participates in β ladder)trans-138.1154-178.1-66.4-175.1-176.2179.50112.4F52 L426 R442K50-F52 HydrophobicContact CB-CE2 4.06Å; K50-L426 HydrophobicContact CB-CD1 4.4Å; K50-L426 PolarHBondContact O-N 3.42Å; K50-R442 CarbonylContact C-O 3.49Å; K50-R442 WeakPolarHBondContact CA-O 3.32Å
51S95Very high94Very high0 Ų029.3 Ų29.30%015%0.15CC..EExtended strand (participates in β ladder)trans-131.6151169.289.20000111.7R423 F424 R442 D443 V444S51-R423 PolarHBondContact OG-NH1 2.92Å; S51-F424 CarbonylContact C-O 3.49Å; S51-F424 WeakPolarHBondContact CA-O 3.46Å; S51-F424 WeakPolarHBondContact CB-O 3.43Å; S51-R442 PolarHBondContact N-O 3.2Å; S51-D443 WeakPolarHBondContact CB-OD1 3.44Å; S51-D443 PolarHBondContact OG-OD1 3.15Å; S51-V444 WeakPolarHBondContact O-CB 3.36Å; S51-V444 PolarHBondContact O-N 3.23Å
52F95.8Very high94.3Very high22 Ų2228.1 Ų28.110%0.09614%0.143CC..EExtended strand (participates in β ladder)trans-133.3149.2-178.8-65.6-97000110.2K50 W81 I89 R423 F424 L426 V444K50-F52 HydrophobicContact CB-CE2 4.06Å; F52-W81 HydrophobicContact CB-CH2 4.12Å; F52-W81 HydrophobicContact CD1-CH2 4.05Å; F52-W81 AromaticContact CD1-CZ3 3.86Å; F52-W81 HydrophobicContact CD1-CZ3 3.86Å; F52-W81 HydrophobicContact CE1-CZ3 4.27Å; F52-W81 HydrophobicContact CG-CH2 4.28Å; F52-W81 HydrophobicContact CG-CZ3 4.32Å; F52-I89 HydrophobicContact CD2-CD1 3.9Å; F52-I89 HydrophobicContact CE2-CD1 3.65Å; F52-I89 HydrophobicContact CE2-CG1 3.79Å; F52-I89 HydrophobicContact CZ-CD1 4.04Å; F52-I89 HydrophobicContact CZ-CG1 3.79Å; F52-R423 CarbonylContact O-C 3.54Å; F52-R423 WeakPolarHBondContact O-CA 3.38Å; F52-R423 WeakPolarHBondContact O-CB 3.16Å; F52-F424 HydrophobicContact CB-CD1 4.09Å; F52-F424 HydrophobicContact CB-CE1 3.42Å; F52-F424 VanDerWaalsContact CB-CE1 3.42Å; F52-F424 HydrophobicContact CB-CE2 4.06Å; F52-F424 HydrophobicContact CB-CZ 3.41Å; F52-F424 VanDerWaalsContact CB-CZ 3.41Å; F52-F424 AromaticContact CD2-CE2 3.88Å; F52-F424 HydrophobicContact CD2-CE2 3.88Å; F52-F424 AromaticContact CD2-CZ 3.93Å; F52-F424 HydrophobicContact CD2-CZ 3.93Å; F52-F424 HydrophobicContact CG-CE1 4.35Å; F52-F424 HydrophobicContact CG-CE2 4.29Å; F52-F424 AromaticContact CG-CZ 3.86Å; F52-F424 HydrophobicContact CG-CZ 3.86Å; F52-F424 PolarHBondContact N-O 3.15Å; F52-F424 PolarHBondContact O-N 2.68Å; F52-L426 HydrophobicContact CD2-CD1 4.29Å; F52-L426 HydrophobicContact CD2-CG 4.5Å; F52-L426 HydrophobicContact CE2-CD1 3.66Å; F52-L426 HydrophobicContact CE2-CG 4.3Å; F52-V444 HydrophobicContact CD1-CB 3.93Å; F52-V444 HydrophobicContact CD1-CG1 4.04Å; F52-V444 HydrophobicContact CD1-CG2 4.35Å; F52-V444 HydrophobicContact CE1-CB 3.98Å; F52-V444 HydrophobicContact CE1-CG1 3.95Å; F52-V444 HydrophobicContact CE1-CG2 3.96Å; F52-V444 HydrophobicContact CZ-CG2 4.12Å
53M93.4Very high94.4Very high32 Ų3229.5 Ų29.516%0.15815%0.154CC..EExtended strand (participates in β ladder)trans-93.5144.9-173.8-60.1-171.778.400113.6N422 R423 L445 N446 E447M53-N422 WeakPolarHBondContact CA-O 3.41Å; M53-N422 WeakPolarHBondContact CE-ND2 3.31Å; M53-R423 HydrophobicContact CG-CG 3.89Å; M53-R423 PolarHBondContact SD-NH2 2.83Å; M53-L445 HydrophobicContact SD-CD2 3.58Å; M53-L445 VanDerWaalsContact SD-CD2 3.58Å; M53-N446 PolarHBondContact N-OD1 2.91Å; M53-N446 PolarHBondContact O-ND2 3.2Å; M53-E447 HydrophobicContact CB-CB 4.1Å; M53-E447 HydrophobicContact CB-CG 3.98Å
54H94Very high94.3Very high1 Ų129.8 Ų29.81%0.00516%0.156CC..  trans-106.4169.8150.4-80.4-120.6000109D56 V58 T71 S73 N422H54-D56 VanDerWaalsContact C-N 3.28Å; H54-D56 WeakPolarHBondContact CB-O 3.47Å; H54-V58 HydrophobicContact CB-CG2 3.84Å; H54-T71 PolarHBondContact CE1-OG1 2.91Å; H54-T71 WeakPolarHBondContact NE2-CB 3.5Å; H54-T71 PolarHBondContact NE2-OG1 3.36Å; H54-S73 PolarHBondContact ND1-OG 3.47Å; H54-N422 PolarHBondContact N-O 2.83Å
55R88.3Confident94.2Very high129 Ų12931.4 Ų31.449%0.48715%0.154SC..SBendtrans-72-26.4174.2-68.4-173.6179-173.2-3112.8E447 R450R55-E447 HydrophobicContact CG-CG 4.41Å; R55-E447 WeakPolarHBondContact CG-OE2 3.16Å; R55-E447 IonicContact NE-OE2 2.91Å; R55-E447 PolarHBondContact NE-OE2 3.07Å; R55-R450 PolarHBondContact O-NE 2.81Å; R55-R450 PolarHBondContact O-NH2 3.42Å
56D92.8Very high94.2Very high50 Ų5032 Ų3227%0.26716%0.158SC..SBendtrans-135179.6178.7-139.7-57.6000111.1H54 V58 V74 D75 N422 R450H54-D56 VanDerWaalsContact C-N 3.28Å; H54-D56 WeakPolarHBondContact CB-O 3.47Å; D56-V58 PolarHBondContact O-N 2.94Å; D56-V74 HydrophobicContact CB-CG2 4.03Å; D56-V74 WeakPolarHBondContact OD1-CG2 3.41Å; D56-D75 HydrophobicContact CB-CB 4.11Å; D56-N422 VanDerWaalsContact O-CA 3.26Å; D56-N422 WeakPolarHBondContact O-CA 3.32Å; D56-N422 VanDerWaalsContact O-CB 3.29Å; D56-N422 WeakPolarHBondContact O-CB 3.4Å; D56-R450 IonicContact OD2-NH2 3.79Å; D56-R450 PolarHBondContact OD2-NH2 3.36Å
57V95.1Very high94.4Very high43 Ų4328.4 Ų28.426%0.26114%0.138SC..  trans-52.8126.6-177.9178.80000110.7S59 S73 V74 K421V57-S59 PolarHBondContact O-N 3.4Å; V57-S73 CarbonylContact O-C 3.42Å; V57-S73 WeakPolarHBondContact O-CA 3.44Å; V57-S73 VanDerWaalsContact O-CB 3.29Å; V57-S73 WeakPolarHBondContact O-CB 3.29Å; V57-V74 HydrophobicContact CB-CG1 4.16Å; V57-V74 HydrophobicContact CB-CG2 3.94Å; V57-V74 HydrophobicContact CG1-CG1 4.4Å; V57-V74 PolarHBondContact O-N 3.3Å; V57-K421 WeakPolarHBondContact CA-O 3.32Å
58V97.5Very high94.5Very high3 Ų328.7 Ų28.72%0.01814%0.138CC..EExtended strand (participates in β ladder)trans-76.7117.6175.5-177.50000108.1H54 D56 V61 A72 S417 K421 F424H54-V58 HydrophobicContact CB-CG2 3.84Å; D56-V58 PolarHBondContact O-N 2.94Å; V58-V61 HydrophobicContact CG1-CG1 4.07Å; V58-A72 CarbonylContact C-O 3.43Å; V58-A72 WeakPolarHBondContact CG1-O 3.41Å; V58-S417 WeakPolarHBondContact O-CB 3.32Å; V58-K421 PolarHBondContact N-O 3.43Å; V58-F424 HydrophobicContact CG1-CB 4.34Å
59S95.9Very high94.7Very high0 Ų028 Ų280%014%0.135CC..EExtended strand (participates in β ladder)trans-96.9-36.4-177.653.40000112.8V57 A72V57-S59 PolarHBondContact O-N 3.4Å; S59-A72 PolarHBondContact N-O 3.44Å; S59-A72 PolarHBondContact OG-O 2.85Å
60H98Very high94.9Very high13 Ų1326.3 Ų26.36%0.0613%0.127CC..EExtended strand (participates in β ladder)trans-129.9141.2-175.9-56.474.1000111.1T71 A72 I102 L105 F325H60-T71 CarbonylContact O-C 3.59Å; H60-T71 WeakPolarHBondContact O-CA 3.43Å; H60-A72 HydrophobicContact CB-CB 4.16Å; H60-A72 PolarHBondContact N-O 2.89Å; H60-A72 VanDerWaalsContact N-O 3.16Å; H60-A72 PolarHBondContact O-N 2.76Å; H60-I102 PolarHBondContact CE1-O 2.91Å; H60-L105 HydrophobicContact CB-CB 4.44Å; H60-F325 AromaticContact CE1-CD1 3.85Å; H60-F325 AromaticContact CE1-CE1 3.52Å
61V98.2Very high95.2Very high8 Ų823.2 Ų23.25%0.04811%0.114CC..EExtended strand (participates in β ladder)trans-131.3139164.8-57.60000108.1V58 I70 T71 C369 A371 V415 F424V58-V61 HydrophobicContact CG1-CG1 4.07Å; V61-I70 CarbonylContact C-O 3.54Å; V61-I70 WeakPolarHBondContact CA-O 3.29Å; V61-T71 HydrophobicContact CG1-CG2 4.13Å; V61-C369 HydrophobicContact CG2-CB 4.1Å; V61-C369 WeakPolarHBondContact CG2-O 3.44Å; V61-C369 PolarHBondContact N-SG 3.48Å; V61-C369 PolarHBondContact O-SG 3.24Å; V61-A371 HydrophobicContact CG2-CB 4.26Å; V61-V415 HydrophobicContact CB-CG1 3.97Å; V61-V415 HydrophobicContact CG1-CG1 4.02Å; V61-V415 HydrophobicContact CG2-CG1 4.43Å; V61-F424 HydrophobicContact CG1-CB 4.17Å
62A97.8Very high95.3Very high16 Ų1623.2 Ų23.213%0.13211%0.114CC..EExtended strand (participates in β ladder)trans-143.3146.917900000109.4I69 I70 L105 I107A62-I69 CarbonylContact O-C 3.57Å; A62-I69 WeakPolarHBondContact O-CA 3.38Å; A62-I70 PolarHBondContact N-O 3.27Å; A62-I70 PolarHBondContact O-N 2.94Å; A62-L105 HydrophobicContact CB-CD2 3.73Å; A62-I107 HydrophobicContact CB-CD1 3.64Å; A62-I107 HydrophobicContact CB-CG1 4.18Å
63A96.8Very high95.3Very high28 Ų2822.2 Ų22.223%0.23111%0.11CC..EExtended strand (participates in β ladder)trans-121.8128.617500000108.6F68 A371 C373A63-F68 CarbonylContact C-O 3.53Å; A63-F68 WeakPolarHBondContact CA-O 3.39Å; A63-A371 HydrophobicContact CB-CB 3.94Å; A63-C373 HydrophobicContact CB-CB 4.44Å
64S94.9Very high95.3Very high6 Ų622.5 Ų22.54%0.04211%0.113CC..  trans-86.8162.7177.479.80000110.8T66 F68S64-T66 WeakPolarHBondContact CB-OG1 3.4Å; S64-T66 PolarHBondContact O-N 2.8Å; S64-T66 PolarHBondContact OG-N 2.85Å; S64-T66 VanDerWaalsContact OG-N 3.12Å; S64-T66 PolarHBondContact OG-OG1 2.86Å; S64-F68 PolarHBondContact N-O 3.4Å; S64-F68 PolarHBondContact OG-N 3.26Å; S64-F68 PolarHBondContact OG-O 3.05Å
65R91.6Very high95.2Very high89 Ų8924.7 Ų24.734%0.33613%0.125SC..THydrogen-bonded Turntrans-73.7-2.2169.8-65.5-166.5176.8176.5-6.2114.1Y109 R374 S378R65-Y109 WeakPolarHBondContact CD-O 3.2Å; R65-Y109 PolarHBondContact NE-O 2.76Å; R65-Y109 PolarHBondContact NH1-O 3.34Å; R65-Y109 PolarHBondContact NH1-OH 3.15Å; R65-Y109 PolarHBondContact NH2-OH 3.09Å; R65-R374 WeakPolarHBondContact O-CD 3.41Å; R65-S378 WeakPolarHBondContact O-CB 3.23Å
66T91.6Very high95.4Very high16 Ų1618.6 Ų18.610%0.09810%0.102CC..THydrogen-bonded Turntrans-106.223.6-178.848.90000111.5S64 F68 G111S64-T66 WeakPolarHBondContact CB-OG1 3.4Å; S64-T66 PolarHBondContact O-N 2.8Å; S64-T66 PolarHBondContact OG-N 2.85Å; S64-T66 VanDerWaalsContact OG-N 3.12Å; S64-T66 PolarHBondContact OG-OG1 2.86Å; T66-F68 WeakPolarHBondContact O-CD2 3.46Å; T66-F68 VanDerWaalsContact O-CE2 3.3Å; T66-F68 WeakPolarHBondContact O-CE2 3.46Å; T66-F68 PolarHBondContact O-N 2.66Å; T66-G111 PolarHBondContact OG1-O 3.02Å
67D93.2Very high95.5Very high16 Ų1617.2 Ų17.29%0.0869%0.094CC..SBendtrans63.120.3178.3-57.1-55.1000114.8K83 H85 S378D67-K83 WeakPolarHBondContact O-CB 2.97Å; D67-K83 PolarHBondContact O-N 3.44Å; D67-H85 IonicContact OD1-CE1 4Å; D67-H85 IonicContact OD1-NE2 3.28Å; D67-H85 PolarHBondContact OD1-NE2 2.92Å; D67-H85 IonicContact OD2-NE2 2.6Å; D67-S378 WeakPolarHBondContact OD2-CB 3.5Å; D67-S378 PolarHBondContact OD2-N 3.1Å; D67-S378 PolarHBondContact OD2-OG 2.84Å
68F95.7Very high95.6Very high15 Ų1515.2 Ų15.27%0.0668%0.082CC..EExtended strand (participates in β ladder)trans-98.4143.2172.5-65.1-69.2000111.5A63 S64 T66 I70 W81 K82 V128 F131A63-F68 CarbonylContact C-O 3.53Å; A63-F68 WeakPolarHBondContact CA-O 3.39Å; S64-F68 PolarHBondContact N-O 3.4Å; S64-F68 PolarHBondContact OG-N 3.26Å; S64-F68 PolarHBondContact OG-O 3.05Å; T66-F68 WeakPolarHBondContact O-CD2 3.46Å; T66-F68 VanDerWaalsContact O-CE2 3.3Å; T66-F68 WeakPolarHBondContact O-CE2 3.46Å; T66-F68 PolarHBondContact O-N 2.66Å; F68-I70 HydrophobicContact CB-CD1 4.37Å; F68-W81 CarbonylContact C-O 3.46Å; F68-W81 WeakPolarHBondContact CA-O 3.43Å; F68-W81 WeakPolarHBondContact CD1-O 3.45Å; F68-K82 HydrophobicContact CD1-CB 4.01Å; F68-K82 HydrophobicContact CD1-CG 4.16Å; F68-K82 HydrophobicContact CE1-CB 3.79Å; F68-K82 HydrophobicContact CE1-CD 3.92Å; F68-K82 HydrophobicContact CE1-CG 3.67Å; F68-K82 HydrophobicContact CZ-CD 4.42Å; F68-K82 HydrophobicContact CZ-CG 4.44Å; F68-V128 HydrophobicContact CB-CG1 3.9Å; F68-V128 HydrophobicContact CD2-CG1 3.88Å; F68-V128 HydrophobicContact CG-CG1 4.17Å; F68-F131 AromaticContact CD1-CE1 3.55Å; F68-F131 HydrophobicContact CD1-CE1 3.55Å; F68-F131 HydrophobicContact CD1-CZ 4.16Å; F68-F131 HydrophobicContact CD2-CE1 4.31Å; F68-F131 HydrophobicContact CE1-CD1 4.4Å; F68-F131 AromaticContact CE1-CE1 3.11Å; F68-F131 HydrophobicContact CE1-CE1 3.11Å; F68-F131 AromaticContact CE1-CZ 3.26Å; F68-F131 HydrophobicContact CE1-CZ 3.26Å; F68-F131 AromaticContact CE2-CE1 3.92Å; F68-F131 HydrophobicContact CE2-CE1 3.92Å; F68-F131 HydrophobicContact CE2-CZ 4.18Å; F68-F131 HydrophobicContact CG-CE1 4.15Å; F68-F131 AromaticContact CZ-CE1 3.33Å; F68-F131 HydrophobicContact CZ-CE1 3.33Å; F68-F131 AromaticContact CZ-CZ 3.27Å; F68-F131 HydrophobicContact CZ-CZ 3.27Å
69I97.4Very high95.5Very high1 Ų115.5 Ų15.51%0.0058%0.083CC..EExtended strand (participates in β ladder)trans-112.8131.7172.3-63157.3000106.6A62 T71 W81 K83 I89 M413 V415A62-I69 CarbonylContact O-C 3.57Å; A62-I69 WeakPolarHBondContact O-CA 3.38Å; I69-T71 HydrophobicContact CG2-CG2 4.13Å; I69-W81 HydrophobicContact CB-CB 4.16Å; I69-W81 PolarHBondContact N-O 3.32Å; I69-W81 PolarHBondContact O-N 3.44Å; I69-K83 HydrophobicContact CD1-CB 4.24Å; I69-I89 HydrophobicContact CD1-CG2 3.59Å; I69-M413 HydrophobicContact CD1-SD 4.03Å; I69-V415 HydrophobicContact CD1-CG2 3.81Å; I69-V415 HydrophobicContact CG1-CG2 4.09Å; I69-V415 HydrophobicContact CG2-CB 4.43Å; I69-V415 HydrophobicContact CG2-CG1 4.11Å; I69-V415 HydrophobicContact CG2-CG2 3.89Å
70I98Very high95.5Very high0 Ų015.5 Ų15.50%08%0.083CC..EExtended strand (participates in β ladder)trans-117132.6175.4-57.594.5000108.5V61 A62 F68 V78 K79 F80 L105 I107 M114 V128V61-I70 CarbonylContact C-O 3.54Å; V61-I70 WeakPolarHBondContact CA-O 3.29Å; A62-I70 PolarHBondContact N-O 3.27Å; A62-I70 PolarHBondContact O-N 2.94Å; F68-I70 HydrophobicContact CB-CD1 4.37Å; I70-V78 HydrophobicContact CG2-CG1 3.49Å; I70-V78 VanDerWaalsContact CG2-CG1 3.49Å; I70-K79 WeakPolarHBondContact CA-O 3.34Å; I70-F80 HydrophobicContact CD1-CD1 4.43Å; I70-F80 HydrophobicContact CD1-CE1 4.37Å; I70-F80 HydrophobicContact CG1-CD1 3.68Å; I70-F80 HydrophobicContact CG1-CE1 3.71Å; I70-F80 HydrophobicContact CG1-CG 4.3Å; I70-F80 HydrophobicContact CG1-CZ 4.34Å; I70-L105 HydrophobicContact CG2-CD1 3.98Å; I70-I107 HydrophobicContact CD1-CD1 3.57Å; I70-I107 HydrophobicContact CD1-CG1 4.43Å; I70-M114 HydrophobicContact CB-CE 4.08Å; I70-M114 HydrophobicContact CB-SD 4.45Å; I70-M114 HydrophobicContact CD1-SD 4.1Å; I70-M114 HydrophobicContact CG1-CE 4.08Å; I70-M114 HydrophobicContact CG1-SD 3.79Å; I70-M114 HydrophobicContact CG2-CE 3.57Å; I70-M114 HydrophobicContact CG2-SD 4.25Å; I70-V128 HydrophobicContact CD1-CG1 4.26Å
71T98.3Very high95.5Very high0 Ų015.1 Ų15.10%08%0.081CC..EExtended strand (participates in β ladder)trans-126.8139178.259.90000108.7H54 H60 V61 I69 V78 K79 W81 F424H54-T71 PolarHBondContact CE1-OG1 2.91Å; H54-T71 WeakPolarHBondContact NE2-CB 3.5Å; H54-T71 PolarHBondContact NE2-OG1 3.36Å; H60-T71 CarbonylContact O-C 3.59Å; H60-T71 WeakPolarHBondContact O-CA 3.43Å; V61-T71 HydrophobicContact CG1-CG2 4.13Å; I69-T71 HydrophobicContact CG2-CG2 4.13Å; T71-V78 WeakPolarHBondContact O-CA 3.42Å; T71-K79 PolarHBondContact N-O 2.89Å; T71-K79 PolarHBondContact O-N 2.89Å; T71-K79 PolarHBondContact OG1-O 3.34Å; T71-W81 PolarHBondContact OG1-NE1 2.99Å; T71-F424 HydrophobicContact CG2-CD1 3.85Å; T71-F424 HydrophobicContact CG2-CD2 4.19Å; T71-F424 HydrophobicContact CG2-CE1 3.89Å; T71-F424 HydrophobicContact CG2-CE2 4.23Å; T71-F424 HydrophobicContact CG2-CG 3.98Å; T71-F424 HydrophobicContact CG2-CZ 4.06Å
72A97.7Very high95.3Very high0 Ų018.9 Ų18.90%010%0.096CC..EExtended strand (participates in β ladder)trans-133.2146.6179.100000111.6V58 S59 H60 H77 V78 I102 L105V58-A72 CarbonylContact C-O 3.43Å; V58-A72 WeakPolarHBondContact CG1-O 3.41Å; S59-A72 PolarHBondContact N-O 3.44Å; S59-A72 PolarHBondContact OG-O 2.85Å; H60-A72 HydrophobicContact CB-CB 4.16Å; H60-A72 PolarHBondContact N-O 2.89Å; H60-A72 VanDerWaalsContact N-O 3.16Å; H60-A72 PolarHBondContact O-N 2.76Å; A72-H77 CarbonylContact C-O 3.58Å; A72-H77 WeakPolarHBondContact CA-O 3.22Å; A72-V78 HydrophobicContact CB-CG2 4.06Å; A72-I102 HydrophobicContact CB-CD1 3.75Å; A72-L105 HydrophobicContact CB-CD1 3.98Å
73S95.7Very high95.1Very high0 Ų018.3 Ų18.30%09%0.091CC..EExtended strand (participates in β ladder)trans-111.4161.2179.126.70000112H54 V57 D75 G76 H77H54-S73 PolarHBondContact ND1-OG 3.47Å; V57-S73 CarbonylContact O-C 3.42Å; V57-S73 WeakPolarHBondContact O-CA 3.44Å; V57-S73 VanDerWaalsContact O-CB 3.29Å; V57-S73 WeakPolarHBondContact O-CB 3.29Å; S73-D75 VanDerWaalsContact CB-OD1 3.27Å; S73-D75 WeakPolarHBondContact CB-OD1 3.32Å; S73-D75 PolarHBondContact O-N 3.41Å; S73-D75 PolarHBondContact OG-OD1 3.12Å; S73-G76 PolarHBondContact O-N 3.01Å; S73-H77 PolarHBondContact N-O 2.95Å; S73-H77 WeakPolarHBondContact OG-CB 3.39Å; S73-H77 PolarHBondContact OG-O 3.35Å
74V93.1Very high94.7Very high38 Ų3819.1 Ų19.123%0.239%0.091CC..THydrogen-bonded Turntrans-63.4-18.5-176.8-65.60000113.9D56 V57 G76 L101D56-V74 HydrophobicContact CB-CG2 4.03Å; D56-V74 WeakPolarHBondContact OD1-CG2 3.41Å; V57-V74 HydrophobicContact CB-CG1 4.16Å; V57-V74 HydrophobicContact CB-CG2 3.94Å; V57-V74 HydrophobicContact CG1-CG1 4.4Å; V57-V74 PolarHBondContact O-N 3.3Å; V74-G76 VanDerWaalsContact C-N 3.29Å; V74-G76 PolarHBondContact O-N 3.06Å; V74-L101 HydrophobicContact CB-CD1 4.16Å; V74-L101 HydrophobicContact CG1-CD1 4.24Å; V74-L101 WeakPolarHBondContact O-CA 3.34Å
75D91.7Very high94.2Very high48 Ų4820.4 Ų20.426%0.25710%0.096SC..THydrogen-bonded Turntrans-86.67.1177.967.4-14.7000113.6D56 S73 H77D56-D75 HydrophobicContact CB-CB 4.11Å; S73-D75 VanDerWaalsContact CB-OD1 3.27Å; S73-D75 WeakPolarHBondContact CB-OD1 3.32Å; S73-D75 PolarHBondContact O-N 3.41Å; S73-D75 PolarHBondContact OG-OD1 3.12Å; D75-H77 IonicContact OD1-CD2 3.19Å; D75-H77 IonicContact OD1-CG 2.85Å; D75-H77 PolarHBondContact OD1-N 2.65Å; D75-H77 IonicContact OD2-CD2 3.89Å; D75-H77 IonicContact OD2-CG 3.57Å
76G92.4Very high93.8Very high0 Ų022.4 Ų22.40%011%0.114CC..SBendtrans89.48.5174.800000114.9S73 V74 C97 H98S73-G76 PolarHBondContact O-N 3.01Å; V74-G76 VanDerWaalsContact C-N 3.29Å; V74-G76 PolarHBondContact O-N 3.06Å; G76-C97 PolarHBondContact O-N 3.13Å; G76-H98 PolarHBondContact O-N 3.34Å
77H95.2Very high93.5Very high22 Ų2229 Ų2910%0.10214%0.144CC..EExtended strand (participates in β ladder)trans-85.9140177.9-74.9-134.9000111.7A72 S73 D75 H94 F95A72-H77 CarbonylContact C-O 3.58Å; A72-H77 WeakPolarHBondContact CA-O 3.22Å; S73-H77 PolarHBondContact N-O 2.95Å; S73-H77 WeakPolarHBondContact OG-CB 3.39Å; S73-H77 PolarHBondContact OG-O 3.35Å; D75-H77 IonicContact OD1-CD2 3.19Å; D75-H77 IonicContact OD1-CG 2.85Å; D75-H77 PolarHBondContact OD1-N 2.65Å; D75-H77 IonicContact OD2-CD2 3.89Å; D75-H77 IonicContact OD2-CG 3.57Å; H77-H94 AromaticContact CE1-CE1 3.77Å; H77-H94 AromaticContact CE1-NE2 3.68Å; H77-H94 AromaticContact CG-NE2 3.55Å; H77-H94 AromaticContact ND1-CE1 3.26Å; H77-H94 PolarHBondContact ND1-CE1 2.99Å; H77-H94 VanDerWaalsContact ND1-CE1 3.26Å; H77-H94 AromaticContact ND1-NE2 2.85Å; H77-H94 PolarHBondContact ND1-NE2 2.87Å; H77-F95 WeakPolarHBondContact CA-O 3.48Å
78V96.4Very high93.3Very high0 Ų029.1 Ų29.10%015%0.148CC..EExtended strand (participates in β ladder)trans-129.6128.5178.6-178.20000109.1I70 T71 A72 F80 H94 F95 C97 I102 T116I70-V78 HydrophobicContact CG2-CG1 3.49Å; I70-V78 VanDerWaalsContact CG2-CG1 3.49Å; T71-V78 WeakPolarHBondContact O-CA 3.42Å; A72-V78 HydrophobicContact CB-CG2 4.06Å; V78-F80 HydrophobicContact CG1-CD2 4.49Å; V78-F80 HydrophobicContact CG1-CE2 4.06Å; V78-H94 PolarHBondContact O-CD2 3Å; V78-F95 PolarHBondContact N-O 3.07Å; V78-F95 PolarHBondContact O-N 2.94Å; V78-C97 HydrophobicContact CG2-CB 3.96Å; V78-C97 WeakPolarHBondContact CG2-SG 3.46Å; V78-I102 HydrophobicContact CG2-CD1 3.7Å; V78-T116 HydrophobicContact CG2-CG2 4.1Å
79K96.4Very high93.3Very high10 Ų1029.6 Ų29.64%0.04315%0.151CC..EExtended strand (participates in β ladder)trans-119.5134.2177.6-64.3179.1-178.6-81.30110.4I70 T71 W81 F91 K93 H94 E447I70-K79 WeakPolarHBondContact CA-O 3.34Å; T71-K79 PolarHBondContact N-O 2.89Å; T71-K79 PolarHBondContact O-N 2.89Å; T71-K79 PolarHBondContact OG1-O 3.34Å; K79-W81 HydrophobicContact CB-CZ2 4.18Å; K79-W81 HydrophobicContact CD-CZ2 3.72Å; K79-F91 HydrophobicContact CB-CE2 4.24Å; K79-F91 HydrophobicContact CD-CE2 4.25Å; K79-F91 HydrophobicContact CG-CE2 4.17Å; K79-K93 WeakPolarHBondContact CA-O 3.32Å; K79-H94 HydrophobicContact CG-CB 4.18Å; K79-E447 WeakPolarHBondContact CE-OE1 3.35Å; K79-E447 IonicContact NZ-OE1 3.76Å; K79-E447 PolarHBondContact NZ-OE1 2.95Å
80F96Very high93.1Very high0 Ų034.5 Ų34.50%017%0.174CC..EExtended strand (participates in β ladder)trans-98.2134.4172.4-72.4-103.8000109.2I70 V78 V92 K93 F95 M114 F126 F131I70-F80 HydrophobicContact CD1-CD1 4.43Å; I70-F80 HydrophobicContact CD1-CE1 4.37Å; I70-F80 HydrophobicContact CG1-CD1 3.68Å; I70-F80 HydrophobicContact CG1-CE1 3.71Å; I70-F80 HydrophobicContact CG1-CG 4.3Å; I70-F80 HydrophobicContact CG1-CZ 4.34Å; V78-F80 HydrophobicContact CG1-CD2 4.49Å; V78-F80 HydrophobicContact CG1-CE2 4.06Å; F80-V92 HydrophobicContact CB-CB 4.27Å; F80-V92 PolarHBondContact O-N 3.07Å; F80-K93 HydrophobicContact CB-CB 4.46Å; F80-K93 PolarHBondContact N-O 3.39Å; F80-K93 PolarHBondContact O-N 3.45Å; F80-F95 AromaticContact CD2-CD2 3.93Å; F80-F95 HydrophobicContact CD2-CD2 3.93Å; F80-F95 AromaticContact CD2-CE2 3.97Å; F80-F95 HydrophobicContact CD2-CE2 3.97Å; F80-F95 AromaticContact CE2-CD2 3.75Å; F80-F95 HydrophobicContact CE2-CD2 3.75Å; F80-F95 AromaticContact CE2-CE2 3.8Å; F80-F95 HydrophobicContact CE2-CE2 3.8Å; F80-M114 HydrophobicContact CE1-SD 3.5Å; F80-M114 WeakPolarHBondContact CE1-SD 3.45Å; F80-M114 HydrophobicContact CE2-SD 4.42Å; F80-M114 HydrophobicContact CZ-CE 4.48Å; F80-M114 HydrophobicContact CZ-SD 3.33Å; F80-M114 WeakPolarHBondContact CZ-SD 3.29Å; F80-F126 HydrophobicContact CE2-CD1 4.31Å; F80-F126 HydrophobicContact CZ-CB 4.19Å; F80-F126 HydrophobicContact CZ-CD1 4.13Å; F80-F126 HydrophobicContact CZ-CG 4.18Å; F80-F131 HydrophobicContact CD1-CD1 4.27Å
81W96.8Very high92.9Very high4 Ų439.1 Ų39.12%0.01519%0.194CC..EExtended strand (participates in β ladder)trans-129.9149.7176.2-4579.9000108.4F52 F68 I69 T71 K79 I89 E90 F91 F424F52-W81 HydrophobicContact CB-CH2 4.12Å; F52-W81 HydrophobicContact CD1-CH2 4.05Å; F52-W81 AromaticContact CD1-CZ3 3.86Å; F52-W81 HydrophobicContact CD1-CZ3 3.86Å; F52-W81 HydrophobicContact CE1-CZ3 4.27Å; F52-W81 HydrophobicContact CG-CH2 4.28Å; F52-W81 HydrophobicContact CG-CZ3 4.32Å; F68-W81 CarbonylContact C-O 3.46Å; F68-W81 WeakPolarHBondContact CA-O 3.43Å; F68-W81 WeakPolarHBondContact CD1-O 3.45Å; I69-W81 HydrophobicContact CB-CB 4.16Å; I69-W81 PolarHBondContact N-O 3.32Å; I69-W81 PolarHBondContact O-N 3.44Å; T71-W81 PolarHBondContact OG1-NE1 2.99Å; K79-W81 HydrophobicContact CB-CZ2 4.18Å; K79-W81 HydrophobicContact CD-CZ2 3.72Å; W81-I89 HydrophobicContact CB-CD1 4.38Å; W81-I89 HydrophobicContact CD2-CD1 4.11Å; W81-I89 HydrophobicContact CE3-CD1 3.8Å; W81-I89 HydrophobicContact CE3-CG1 4.37Å; W81-I89 HydrophobicContact CG-CD1 4.36Å; W81-I89 HydrophobicContact CZ3-CD1 4.43Å; W81-E90 CarbonylContact C-O 3.58Å; W81-E90 WeakPolarHBondContact CA-O 3.48Å; W81-E90 WeakPolarHBondContact CB-O 3.41Å; W81-F91 HydrophobicContact CD2-CD2 4.4Å; W81-F91 HydrophobicContact CE3-CB 3.79Å; W81-F91 HydrophobicContact CE3-CD2 4.24Å; W81-F91 HydrophobicContact CH2-CB 4.45Å; W81-F91 HydrophobicContact CH2-CD2 4.12Å; W81-F91 HydrophobicContact CZ2-CD2 4.27Å; W81-F91 HydrophobicContact CZ3-CB 3.7Å; W81-F91 HydrophobicContact CZ3-CD2 4.12Å; W81-F91 HydrophobicContact CZ3-CG 4.38Å; W81-F424 AromaticContact CD2-CZ 3.97Å; W81-F424 HydrophobicContact CD2-CZ 3.97Å; W81-F424 AromaticContact CE2-CE1 3.73Å; W81-F424 AromaticContact CE2-CZ 3.48Å; W81-F424 VanDerWaalsContact CE2-CZ 3.48Å; W81-F424 HydrophobicContact CE3-CZ 4.39Å; W81-F424 HydrophobicContact CH2-CE1 4.13Å; W81-F424 HydrophobicContact CH2-CZ 4.01Å; W81-F424 AromaticContact CZ2-CE1 3.45Å; W81-F424 HydrophobicContact CZ2-CE1 3.45Å; W81-F424 VanDerWaalsContact CZ2-CE1 3.45Å; W81-F424 AromaticContact CZ2-CZ 3.54Å; W81-F424 HydrophobicContact CZ2-CZ 3.54Å; W81-F424 HydrophobicContact CZ3-CZ 4.4Å; W81-F424 AromaticContact NE1-CE1 3.9Å; W81-F424 AromaticContact NE1-CZ 3.75Å
82K94Very high92.5Very high87 Ų8741.2 Ų41.238%0.37821%0.207SC..EExtended strand (participates in β ladder)trans-107.5129.3173.9-171.8174.6-177.9-177.50108.7F68 L84 I89 E90 V92F68-K82 HydrophobicContact CD1-CB 4.01Å; F68-K82 HydrophobicContact CD1-CG 4.16Å; F68-K82 HydrophobicContact CE1-CB 3.79Å; F68-K82 HydrophobicContact CE1-CD 3.92Å; F68-K82 HydrophobicContact CE1-CG 3.67Å; F68-K82 HydrophobicContact CZ-CD 4.42Å; F68-K82 HydrophobicContact CZ-CG 4.44Å; K82-L84 HydrophobicContact CD-CD2 4.06Å; K82-L84 HydrophobicContact CG-CD2 4.17Å; K82-L84 PolarHBondContact O-N 2.94Å; K82-I89 CarbonylContact O-C 3.58Å; K82-I89 VanDerWaalsContact O-CA 3.26Å; K82-I89 WeakPolarHBondContact O-CA 3.45Å; K82-E90 PolarHBondContact N-O 2.99Å; K82-E90 PolarHBondContact O-N 2.96Å; K82-V92 HydrophobicContact CB-CG2 3.71Å
83K93.3Very high92.3Very high5 Ų544.4 Ų44.42%0.02222%0.221CC..EExtended strand (participates in β ladder)trans-74.9123.4167.6-172.9-174.9-179.4-128.70108.5D67 I69 H85 C373 R374 D411 M413D67-K83 WeakPolarHBondContact O-CB 2.97Å; D67-K83 PolarHBondContact O-N 3.44Å; I69-K83 HydrophobicContact CD1-CB 4.24Å; K83-H85 PolarHBondContact NZ-CE1 3.41Å; K83-H85 PolarHBondContact NZ-ND1 2.96Å; K83-C373 HydrophobicContact CD-CB 3.91Å; K83-R374 PolarHBondContact NZ-O 3.06Å; K83-D411 WeakPolarHBondContact CE-OD2 3.48Å; K83-D411 PolarHBondContact NZ-O 2.8Å; K83-D411 IonicContact NZ-OD2 3.81Å; K83-D411 PolarHBondContact NZ-OD2 2.87Å; K83-D411 VanDerWaalsContact NZ-OD2 3.15Å; K83-M413 HydrophobicContact CD-CE 4.49Å; K83-M413 HydrophobicContact CD-SD 4.38Å; K83-M413 HydrophobicContact CG-CE 4.24Å; K83-M413 HydrophobicContact CG-SD 4.35Å
84L89.7Confident92.2Very high45 Ų4547.6 Ų47.624%0.23624%0.236CC..EExtended strand (participates in β ladder)trans-103.6107.8170.9-57.9179.2000106.6K82 N86 E87 G88 E90K82-L84 HydrophobicContact CD-CD2 4.06Å; K82-L84 HydrophobicContact CG-CD2 4.17Å; K82-L84 PolarHBondContact O-N 2.94Å; L84-N86 PolarHBondContact O-N 2.82Å; L84-E87 HydrophobicContact CB-CB 3.71Å; L84-E87 PolarHBondContact O-N 3.07Å; L84-G88 PolarHBondContact N-O 3.03Å; L84-G88 PolarHBondContact O-N 2.86Å; L84-G88 VanDerWaalsContact O-O 3.14Å; L84-E90 HydrophobicContact CD1-CB 3.93Å; L84-E90 HydrophobicContact CG-CB 4.34Å
85H83.7Confident92.1Very high32 Ų3247.7 Ų47.715%0.14823%0.233CC..THydrogen-bonded Turntrans-59.9125.4-174-71.1-97.8000110.4D67 K83 E87 R374 V376 P377 D411D67-H85 IonicContact OD1-CE1 4Å; D67-H85 IonicContact OD1-NE2 3.28Å; D67-H85 PolarHBondContact OD1-NE2 2.92Å; D67-H85 IonicContact OD2-NE2 2.6Å; K83-H85 PolarHBondContact NZ-CE1 3.41Å; K83-H85 PolarHBondContact NZ-ND1 2.96Å; H85-E87 PolarHBondContact O-N 3.47Å; H85-R374 PolarHBondContact CE1-O 3.48Å; H85-V376 PolarHBondContact CE1-O 3.18Å; H85-P377 HydrophobicContact CB-CG 4.17Å; H85-P377 VanDerWaalsContact CE1-N 3.29Å; H85-P377 WeakPolarHBondContact NE2-CA 3.17Å; H85-D411 VanDerWaalsContact CA-OD2 3.32Å; H85-D411 WeakPolarHBondContact CA-OD2 3.36Å
86N84.1Confident92.1Very high132 Ų13254.4 Ų54.471%0.70626%0.255SS*.THydrogen-bonded Turntrans67.64.2-172.4-51.1-64.9000116.5L84 D411L84-N86 PolarHBondContact O-N 2.82Å; N86-D411 PolarHBondContact N-OD2 3.3Å
87E85.3Confident91.9Very high155 Ų15555 Ų5572%0.72426%0.259SS*.THydrogen-bonded Turntrans-120.1-14.7179.2-65.4178.1-165.800112.7L84 H85L84-E87 HydrophobicContact CB-CB 3.71Å; L84-E87 PolarHBondContact O-N 3.07Å; H85-E87 PolarHBondContact O-N 3.47Å
88G89.4Confident91.8Very high17 Ų1754 Ų5418%0.17525%0.254CS..EExtended strand (participates in β ladder)trans106.6-130.9177.500000112.3L84L84-G88 PolarHBondContact N-O 3.03Å; L84-G88 PolarHBondContact O-N 2.86Å; L84-G88 VanDerWaalsContact O-O 3.14Å
89I94.4Very high91.3Very high26 Ų2658.3 Ų58.313%0.13329%0.29CS..EExtended strand (participates in β ladder)trans-131.2147.317970.9168.6000111.6F52 I69 W81 K82 M413 F424 L426F52-I89 HydrophobicContact CD2-CD1 3.9Å; F52-I89 HydrophobicContact CE2-CD1 3.65Å; F52-I89 HydrophobicContact CE2-CG1 3.79Å; F52-I89 HydrophobicContact CZ-CD1 4.04Å; F52-I89 HydrophobicContact CZ-CG1 3.79Å; I69-I89 HydrophobicContact CD1-CG2 3.59Å; W81-I89 HydrophobicContact CB-CD1 4.38Å; W81-I89 HydrophobicContact CD2-CD1 4.11Å; W81-I89 HydrophobicContact CE3-CD1 3.8Å; W81-I89 HydrophobicContact CE3-CG1 4.37Å; W81-I89 HydrophobicContact CG-CD1 4.36Å; W81-I89 HydrophobicContact CZ3-CD1 4.43Å; K82-I89 CarbonylContact O-C 3.58Å; K82-I89 VanDerWaalsContact O-CA 3.26Å; K82-I89 WeakPolarHBondContact O-CA 3.45Å; I89-M413 HydrophobicContact CG2-CE 3.95Å; I89-M413 HydrophobicContact CG2-SD 3.74Å; I89-F424 HydrophobicContact CD1-CE2 3.79Å; I89-F424 HydrophobicContact CD1-CZ 3.97Å; I89-L426 HydrophobicContact CD1-CD1 3.84Å; I89-L426 HydrophobicContact CD1-CD2 4.34Å; I89-L426 HydrophobicContact CG1-CD1 3.91Å; I89-L426 HydrophobicContact CG2-CD1 4.07Å
90E93Very high90.7Very high103 Ų10358.7 Ų58.748%0.48130%0.296SS..EExtended strand (participates in β ladder)trans-116.6138175.7-177.5-177.3-167.500110W81 K82 L84W81-E90 CarbonylContact C-O 3.58Å; W81-E90 WeakPolarHBondContact CA-O 3.48Å; W81-E90 WeakPolarHBondContact CB-O 3.41Å; K82-E90 PolarHBondContact N-O 2.99Å; K82-E90 PolarHBondContact O-N 2.96Å; L84-E90 HydrophobicContact CD1-CB 3.93Å; L84-E90 HydrophobicContact CG-CB 4.34Å
91F93.5Very high90.5Very high97 Ų9761.5 Ų61.543%0.42531%0.311SS..EExtended strand (participates in β ladder)trans-73.8127.9171.6172.6-99.9000110.4K79 W81 H94K79-F91 HydrophobicContact CB-CE2 4.24Å; K79-F91 HydrophobicContact CD-CE2 4.25Å; K79-F91 HydrophobicContact CG-CE2 4.17Å; W81-F91 HydrophobicContact CD2-CD2 4.4Å; W81-F91 HydrophobicContact CE3-CB 3.79Å; W81-F91 HydrophobicContact CE3-CD2 4.24Å; W81-F91 HydrophobicContact CH2-CB 4.45Å; W81-F91 HydrophobicContact CH2-CD2 4.12Å; W81-F91 HydrophobicContact CZ2-CD2 4.27Å; W81-F91 HydrophobicContact CZ3-CB 3.7Å; W81-F91 HydrophobicContact CZ3-CD2 4.12Å; W81-F91 HydrophobicContact CZ3-CG 4.38Å; F91-H94 HydrophobicContact CE2-CB 3.9Å; F91-H94 HydrophobicContact CZ-CB 3.56Å
92V91.5Very high90.3Very high44 Ų4461.3 Ų61.327%0.26731%0.31SS..EExtended strand (participates in β ladder)trans-105.5-58.1-176.9-178.20000111.5F80 K82 F131F80-V92 HydrophobicContact CB-CB 4.27Å; F80-V92 PolarHBondContact O-N 3.07Å; K82-V92 HydrophobicContact CB-CG2 3.71Å; V92-F131 HydrophobicContact CG1-CD1 3.78Å; V92-F131 HydrophobicContact CG1-CD2 3.64Å; V92-F131 HydrophobicContact CG1-CE1 3.83Å; V92-F131 HydrophobicContact CG1-CE2 3.65Å; V92-F131 HydrophobicContact CG1-CG 3.69Å; V92-F131 HydrophobicContact CG1-CZ 3.74Å
93K93Very high90.4Very high67 Ų6757.9 Ų57.929%0.29130%0.297SS..EExtended strand (participates in β ladder)trans-154.6149.8-171.5-157.3166-179.6-179.30111.3K79 F80 F95 F131 D132K79-K93 WeakPolarHBondContact CA-O 3.32Å; F80-K93 HydrophobicContact CB-CB 4.46Å; F80-K93 PolarHBondContact N-O 3.39Å; F80-K93 PolarHBondContact O-N 3.45Å; K93-F95 HydrophobicContact CB-CE2 4.19Å; K93-F95 HydrophobicContact CD-CE1 4.47Å; K93-F95 HydrophobicContact CD-CE2 3.61Å; K93-F95 HydrophobicContact CD-CZ 3.5Å; K93-F95 VanDerWaalsContact CD-CZ 3.5Å; K93-F95 HydrophobicContact CG-CD2 4.36Å; K93-F95 HydrophobicContact CG-CE2 3.69Å; K93-F95 HydrophobicContact CG-CZ 3.96Å; K93-F131 HydrophobicContact CB-CB 4.43Å; K93-F131 HydrophobicContact CD-CB 3.75Å; K93-F131 VanDerWaalsContact CD-O 3.27Å; K93-F131 WeakPolarHBondContact CD-O 3.12Å; K93-F131 WeakPolarHBondContact CE-O 3.34Å; K93-F131 PolarHBondContact NZ-O 3.29Å; K93-D132 IonicContact NZ-OD1 3.08Å; K93-D132 PolarHBondContact NZ-OD1 3.39Å
94H93.3Very high90.5Very high68 Ų6858.4 Ų58.432%0.31530%0.299SS..EExtended strand (participates in β ladder)trans-127132.9176.7167.2-142.5000109.6H77 V78 K79 F91H77-H94 AromaticContact CE1-CE1 3.77Å; H77-H94 AromaticContact CE1-NE2 3.68Å; H77-H94 AromaticContact CG-NE2 3.55Å; H77-H94 AromaticContact ND1-CE1 3.26Å; H77-H94 PolarHBondContact ND1-CE1 2.99Å; H77-H94 VanDerWaalsContact ND1-CE1 3.26Å; H77-H94 AromaticContact ND1-NE2 2.85Å; H77-H94 PolarHBondContact ND1-NE2 2.87Å; V78-H94 PolarHBondContact O-CD2 3Å; K79-H94 HydrophobicContact CG-CB 4.18Å; F91-H94 HydrophobicContact CE2-CB 3.9Å; F91-H94 HydrophobicContact CZ-CB 3.56Å
95F91.9Very high90.9Very high40 Ų4056.9 Ų56.918%0.17529%0.291CS..EExtended strand (participates in β ladder)trans-120.1135.3173.1-65.7-86.8000110.6H77 V78 F80 K93 C97 F126 F131H77-F95 WeakPolarHBondContact CA-O 3.48Å; V78-F95 PolarHBondContact N-O 3.07Å; V78-F95 PolarHBondContact O-N 2.94Å; F80-F95 AromaticContact CD2-CD2 3.93Å; F80-F95 HydrophobicContact CD2-CD2 3.93Å; F80-F95 AromaticContact CD2-CE2 3.97Å; F80-F95 HydrophobicContact CD2-CE2 3.97Å; F80-F95 AromaticContact CE2-CD2 3.75Å; F80-F95 HydrophobicContact CE2-CD2 3.75Å; F80-F95 AromaticContact CE2-CE2 3.8Å; F80-F95 HydrophobicContact CE2-CE2 3.8Å; K93-F95 HydrophobicContact CB-CE2 4.19Å; K93-F95 HydrophobicContact CD-CE1 4.47Å; K93-F95 HydrophobicContact CD-CE2 3.61Å; K93-F95 HydrophobicContact CD-CZ 3.5Å; K93-F95 VanDerWaalsContact CD-CZ 3.5Å; K93-F95 HydrophobicContact CG-CD2 4.36Å; K93-F95 HydrophobicContact CG-CE2 3.69Å; K93-F95 HydrophobicContact CG-CZ 3.96Å; F95-C97 VanDerWaalsContact C-N 3.34Å; F95-C97 WeakPolarHBondContact CB-SG 3.45Å; F95-C97 PolarHBondContact O-N 3.33Å; F95-F126 HydrophobicContact CD1-CE1 4.38Å; F95-F126 HydrophobicContact CD2-CE1 4.22Å; F95-F126 HydrophobicContact CE2-CD1 4.5Å; F95-F126 HydrophobicContact CE2-CE1 4.39Å; F95-F126 HydrophobicContact CG-CE1 4.19Å; F95-F131 VanDerWaalsContact CZ-O 3.25Å; F95-F131 WeakPolarHBondContact CZ-O 3.37Å
96R90.9Very high91.5Very high188 Ų18856.3 Ų56.371%0.70929%0.291SS*.EExtended strand (participates in β ladder)trans-85.785.9157-177.4175.7-175.9-175.32.6107
97C89.2Confident92.2Very high13 Ų1351.3 Ų51.39%0.08826%0.263CS..  trans-70.9-59.5-174.6-66.70000109.8G76 V78 F95 K124 F126G76-C97 PolarHBondContact O-N 3.13Å; V78-C97 HydrophobicContact CG2-CB 3.96Å; V78-C97 WeakPolarHBondContact CG2-SG 3.46Å; F95-C97 VanDerWaalsContact C-N 3.34Å; F95-C97 WeakPolarHBondContact CB-SG 3.45Å; F95-C97 PolarHBondContact O-N 3.33Å; C97-K124 VanDerWaalsContact C-CE 3.41Å; C97-K124 HydrophobicContact CB-CD 4.01Å; C97-K124 WeakPolarHBondContact O-CE 3.38Å; C97-F126 WeakPolarHBondContact SG-CZ 3.29Å
98H91.5Very high92.7Very high2 Ų244.2 Ų44.21%0.00923%0.231CC..  trans-113.7155.3-168-66.4-76.2000112G76 G100 I102 T116 S118 D120 S122G76-H98 PolarHBondContact O-N 3.34Å; H98-G100 WeakPolarHBondContact CB-O 3.19Å; H98-I102 HydrophobicContact CB-CG1 4.45Å; H98-T116 PolarHBondContact NE2-OG1 2.93Å; H98-S118 WeakPolarHBondContact ND1-CB 3.29Å; H98-D120 WeakPolarHBondContact CA-OD2 3.08Å; H98-D120 VanDerWaalsContact CB-OD2 3.29Å; H98-D120 WeakPolarHBondContact CB-OD2 3.2Å; H98-D120 IonicContact CG-OD2 2.78Å; H98-D120 IonicContact ND1-OD1 3.4Å; H98-D120 PolarHBondContact ND1-OD1 2.85Å; H98-D120 IonicContact ND1-OD2 2.74Å; H98-D120 PolarHBondContact ND1-OD2 2.9Å; H98-D120 VanDerWaalsContact ND1-OD2 3.07Å; H98-S122 PolarHBondContact CE1-OG 3.25Å; H98-S122 PolarHBondContact ND1-OG 2.97Å; H98-S122 VanDerWaalsContact ND1-OG 3.08Å
99A86.8Confident92.9Very high90 Ų9047.5 Ų47.574%0.74424%0.238SC*.SBendtrans-88.2-13.7171.700000112.1D120A99-D120 PolarHBondContact N-OD2 3.39Å
100G84.6Confident92.7Very high17 Ų1748.7 Ų48.718%0.17525%0.245CC..SBendtrans-128-174.917700000112.5H98 I102 S118H98-G100 WeakPolarHBondContact CB-O 3.19Å; G100-I102 PolarHBondContact O-N 3.02Å; G100-S118 PolarHBondContact O-OG 3.19Å
101L90Very high92.8Very high60 Ų6043.8 Ų43.831%0.31422%0.222SC..  trans-59.8131.4-179.7-175.5130.4000111.4V74 T103 S118 C119V74-L101 HydrophobicContact CB-CD1 4.16Å; V74-L101 HydrophobicContact CG1-CD1 4.24Å; V74-L101 WeakPolarHBondContact O-CA 3.34Å; L101-T103 HydrophobicContact CD2-CG2 4.34Å; L101-T103 PolarHBondContact O-N 2.95Å; L101-S118 VanDerWaalsContact O-CA 3.26Å; L101-S118 WeakPolarHBondContact O-CA 3.43Å; L101-S118 WeakPolarHBondContact O-CB 3.4Å; L101-S118 PolarHBondContact O-OG 3.25Å; L101-C119 PolarHBondContact N-SG 3.42Å; L101-C119 PolarHBondContact O-N 3.1Å
102I94.3Very high92.8Very high0 Ų041.2 Ų41.20%022%0.215CC..EExtended strand (participates in β ladder)trans-70.7118.2170.7-67.9165.4000107.6H60 A72 V78 H98 G100 M117H60-I102 PolarHBondContact CE1-O 2.91Å; A72-I102 HydrophobicContact CB-CD1 3.75Å; V78-I102 HydrophobicContact CG2-CD1 3.7Å; H98-I102 HydrophobicContact CB-CG1 4.45Å; G100-I102 PolarHBondContact O-N 3.02Å; I102-M117 CarbonylContact C-O 3.57Å; I102-M117 WeakPolarHBondContact CA-O 3.35Å
103T94.4Very high93Very high15 Ų1539.4 Ų39.49%0.09220%0.204CC..EExtended strand (participates in β ladder)trans-84.6-35.2-179.951.80000111.5L101 M117 C119 P143 R164L101-T103 HydrophobicContact CD2-CG2 4.34Å; L101-T103 PolarHBondContact O-N 2.95Å; T103-M117 PolarHBondContact N-O 3.06Å; T103-M117 WeakPolarHBondContact OG1-CG 3.48Å; T103-M117 PolarHBondContact OG1-O 3.39Å; T103-C119 HydrophobicContact CG2-CB 4.35Å; T103-P143 WeakPolarHBondContact CB-O 3.47Å; T103-P143 WeakPolarHBondContact CG2-O 3.49Å; T103-P143 PolarHBondContact OG1-O 2.96Å; T103-R164 VanDerWaalsContact CG2-NH2 3.34Å
104H96.5Very high93.3Very high16 Ų1636.2 Ų36.27%0.07419%0.19CC..EExtended strand (participates in β ladder)trans-153.3152.5174.7-149.551.4000112.8Y115 M117 G146H104-Y115 PolarHBondContact CD2-OH 2.94Å; H104-M117 HydrophobicContact CB-CE 4.06Å; H104-M117 HydrophobicContact CB-CG 3.43Å; H104-M117 VanDerWaalsContact CB-CG 3.43Å; H104-M117 HydrophobicContact CB-SD 3.47Å; H104-M117 WeakPolarHBondContact CB-SD 3.45Å; H104-M117 PolarHBondContact N-O 3.41Å; H104-M117 WeakPolarHBondContact O-CG 3.32Å; H104-M117 PolarHBondContact O-N 3.37Å; H104-G146 PolarHBondContact CD2-N 2.65Å; H104-G146 PolarHBondContact CD2-O 2.87Å; H104-G146 VanDerWaalsContact CD2-O 3.22Å; H104-G146 PolarHBondContact NE2-O 3.47Å
105L97.2Very high93.5Very high13 Ų1333 Ų337%0.06818%0.175CC..EExtended strand (participates in β ladder)trans-140.4127173.9-179.9160000107.6H60 A62 I70 A72 M114 Y115 T116H60-L105 HydrophobicContact CB-CB 4.44Å; A62-L105 HydrophobicContact CB-CD2 3.73Å; I70-L105 HydrophobicContact CG2-CD1 3.98Å; A72-L105 HydrophobicContact CB-CD1 3.98Å; L105-M114 HydrophobicContact CD1-CE 3.74Å; L105-M114 HydrophobicContact CD2-CE 3.82Å; L105-M114 HydrophobicContact CG-CE 3.72Å; L105-Y115 WeakPolarHBondContact CA-O 3.29Å; L105-T116 HydrophobicContact CB-CG2 4.36Å; L105-T116 HydrophobicContact CD1-CG2 3.81Å; L105-T116 HydrophobicContact CG-CG2 3.96Å
106S97.3Very high93.8Very high19 Ų1931.1 Ų31.113%0.13317%0.166CC..EExtended strand (participates in β ladder)trans-142.5141.1179.2-170.90000111.4M114 Y115 W148S106-M114 VanDerWaalsContact O-CA 3.23Å; S106-M114 WeakPolarHBondContact O-CA 3.37Å; S106-M114 WeakPolarHBondContact O-CB 3.43Å; S106-Y115 VanDerWaalsContact CB-CZ 3.48Å; S106-Y115 WeakPolarHBondContact CB-OH 3.41Å; S106-Y115 PolarHBondContact N-O 3.44Å; S106-Y115 PolarHBondContact O-N 3.29Å; S106-W148 PolarHBondContact O-NE1 2.81Å
107I97.4Very high94Very high27 Ų2722.1 Ų22.114%0.13813%0.133CC..EExtended strand (participates in β ladder)trans-104.8138.4175.4-52175.1000107.4A62 I70 L113 M114 V128A62-I107 HydrophobicContact CB-CD1 3.64Å; A62-I107 HydrophobicContact CB-CG1 4.18Å; I70-I107 HydrophobicContact CD1-CD1 3.57Å; I70-I107 HydrophobicContact CD1-CG1 4.43Å; I107-L113 WeakPolarHBondContact CA-O 3.39Å; I107-L113 WeakPolarHBondContact CG2-O 3.13Å; I107-M114 HydrophobicContact CB-CB 4.41Å; I107-M114 HydrophobicContact CG1-CB 3.99Å; I107-V128 HydrophobicContact CG2-CG2 4.47Å
108N96Very high94.3Very high6 Ų621.5 Ų21.53%0.03213%0.128CC..  trans-69.8165.8177.775.7-18.6000111.6N110 G111 T112 L113 W148N108-N110 VanDerWaalsContact C-N 3.31Å; N108-N110 PolarHBondContact ND2-OD1 2.85Å; N108-N110 PolarHBondContact O-N 2.95Å; N108-N110 VanDerWaalsContact O-N 3.14Å; N108-N110 PolarHBondContact OD1-OD1 3.5Å; N108-G111 PolarHBondContact O-N 3.5Å; N108-G111 PolarHBondContact OD1-N 3.37Å; N108-T112 PolarHBondContact ND2-OG1 2.74Å; N108-T112 PolarHBondContact OD1-N 2.9Å; N108-L113 HydrophobicContact CB-CB 4.39Å; N108-L113 PolarHBondContact N-O 2.98Å; N108-L113 PolarHBondContact OD1-N 3.31Å; N108-L113 PolarHBondContact OD1-O 3Å; N108-L113 VanDerWaalsContact OD1-O 3.1Å; N108-W148 VanDerWaalsContact CA-CD1 3.46Å; N108-W148 HydrophobicContact CB-CB 4.22Å; N108-W148 HydrophobicContact CB-CD2 3.65Å; N108-W148 HydrophobicContact CB-CE3 4.18Å; N108-W148 HydrophobicContact CB-CG 3.66Å; N108-W148 VanDerWaalsContact N-CD1 3.31Å
109Y93.8Very high94.4Very high86 Ų8623.6 Ų23.634%0.33714%0.142SC..THydrogen-bonded Turntrans-53.3-39.8-170.6-175.3-109.9000116.1R65 G111 P152 Y199R65-Y109 WeakPolarHBondContact CD-O 3.2Å; R65-Y109 PolarHBondContact NE-O 2.76Å; R65-Y109 PolarHBondContact NH1-O 3.34Å; R65-Y109 PolarHBondContact NH1-OH 3.15Å; R65-Y109 PolarHBondContact NH2-OH 3.09Å; Y109-G111 VanDerWaalsContact C-N 3.34Å; Y109-P152 HydrophobicContact CD1-CG 3.69Å; Y109-P152 HydrophobicContact CE1-CG 4.49Å; Y109-Y199 AromaticContact CD2-CD1 3.88Å; Y109-Y199 HydrophobicContact CD2-CD1 3.88Å; Y109-Y199 AromaticContact CD2-CD2 3.45Å; Y109-Y199 HydrophobicContact CD2-CD2 3.45Å; Y109-Y199 VanDerWaalsContact CD2-CD2 3.45Å; Y109-Y199 HydrophobicContact CD2-CE1 4.12Å; Y109-Y199 AromaticContact CD2-CE2 3.7Å; Y109-Y199 HydrophobicContact CD2-CE2 3.7Å; Y109-Y199 AromaticContact CD2-CG 3.55Å; Y109-Y199 HydrophobicContact CD2-CG 3.55Å; Y109-Y199 AromaticContact CE2-CD2 3.96Å; Y109-Y199 HydrophobicContact CE2-CD2 3.96Å; Y109-Y199 HydrophobicContact CE2-CG 4Å; Y109-Y199 AromaticContact CG-CD1 3.82Å; Y109-Y199 HydrophobicContact CG-CD1 3.82Å; Y109-Y199 HydrophobicContact CG-CD2 4.22Å; Y109-Y199 AromaticContact CG-CE1 3.96Å; Y109-Y199 HydrophobicContact CG-CE1 3.96Å; Y109-Y199 HydrophobicContact CG-CE2 4.33Å; Y109-Y199 AromaticContact CG-CG 3.97Å; Y109-Y199 HydrophobicContact CG-CG 3.97Å
110N91.4Very high94.8Very high51 Ų5121.8 Ų21.827%0.27312%0.12SC..THydrogen-bonded Turntrans-88.7-1.5-17964.7-10.4000113.1N108 T112 P152N108-N110 VanDerWaalsContact C-N 3.31Å; N108-N110 PolarHBondContact ND2-OD1 2.85Å; N108-N110 PolarHBondContact O-N 2.95Å; N108-N110 VanDerWaalsContact O-N 3.14Å; N108-N110 PolarHBondContact OD1-OD1 3.5Å; N110-T112 HydrophobicContact CB-CG2 4.46Å; N110-T112 PolarHBondContact ND2-OG1 3.25Å; N110-T112 PolarHBondContact OD1-N 3.05Å; N110-T112 PolarHBondContact OD1-OG1 3.31Å; N110-P152 HydrophobicContact CB-CB 4.31Å; N110-P152 HydrophobicContact CB-CG 4.02Å
111G93.5Very high95.3Very high1 Ų126.9 Ų26.91%0.0113%0.134CC..SBendtrans78.513.5176.300000115.2T66 N108 Y109 V128T66-G111 PolarHBondContact OG1-O 3.02Å; N108-G111 PolarHBondContact O-N 3.5Å; N108-G111 PolarHBondContact OD1-N 3.37Å; Y109-G111 VanDerWaalsContact C-N 3.34Å; G111-V128 WeakPolarHBondContact O-CB 3.45Å
112T94.1Very high95.5Very high43 Ų4324.6 Ų24.626%0.26412%0.123SC..SBendtrans-95.8-27.1-174.266.20000113.2N108 N110 V128N108-T112 PolarHBondContact ND2-OG1 2.74Å; N108-T112 PolarHBondContact OD1-N 2.9Å; N110-T112 HydrophobicContact CB-CG2 4.46Å; N110-T112 PolarHBondContact ND2-OG1 3.25Å; N110-T112 PolarHBondContact OD1-N 3.05Å; N110-T112 PolarHBondContact OD1-OG1 3.31Å; T112-V128 PolarHBondContact O-N 3.03Å
113L96.6Very high95.7Very high6 Ų624.6 Ų24.63%0.03112%0.123CC..EExtended strand (participates in β ladder)trans-122.3147.7178.1-63.3174.6000110I107 N108 F126 I134 W148 A157I107-L113 WeakPolarHBondContact CA-O 3.39Å; I107-L113 WeakPolarHBondContact CG2-O 3.13Å; N108-L113 HydrophobicContact CB-CB 4.39Å; N108-L113 PolarHBondContact N-O 2.98Å; N108-L113 PolarHBondContact OD1-N 3.31Å; N108-L113 PolarHBondContact OD1-O 3Å; N108-L113 VanDerWaalsContact OD1-O 3.1Å; L113-F126 WeakPolarHBondContact CA-O 3.35Å; L113-I134 HydrophobicContact CD2-CD1 3.66Å; L113-W148 HydrophobicContact CB-CH2 3.78Å; L113-W148 HydrophobicContact CB-CZ2 3.87Å; L113-W148 HydrophobicContact CD1-CH2 4.17Å; L113-W148 HydrophobicContact CD1-CZ3 4.33Å; L113-A157 HydrophobicContact CD1-CB 3.81Å
114M97.5Very high95.8Very high0 Ų024.8 Ų24.80%012%0.123CC..EExtended strand (participates in β ladder)trans-140.4158.5166.969.5179.7-65.100110.2I70 F80 L105 S106 I107 T116 I125 F126 V128I70-M114 HydrophobicContact CB-CE 4.08Å; I70-M114 HydrophobicContact CB-SD 4.45Å; I70-M114 HydrophobicContact CD1-SD 4.1Å; I70-M114 HydrophobicContact CG1-CE 4.08Å; I70-M114 HydrophobicContact CG1-SD 3.79Å; I70-M114 HydrophobicContact CG2-CE 3.57Å; I70-M114 HydrophobicContact CG2-SD 4.25Å; F80-M114 HydrophobicContact CE1-SD 3.5Å; F80-M114 WeakPolarHBondContact CE1-SD 3.45Å; F80-M114 HydrophobicContact CE2-SD 4.42Å; F80-M114 HydrophobicContact CZ-CE 4.48Å; F80-M114 HydrophobicContact CZ-SD 3.33Å; F80-M114 WeakPolarHBondContact CZ-SD 3.29Å; L105-M114 HydrophobicContact CD1-CE 3.74Å; L105-M114 HydrophobicContact CD2-CE 3.82Å; L105-M114 HydrophobicContact CG-CE 3.72Å; S106-M114 VanDerWaalsContact O-CA 3.23Å; S106-M114 WeakPolarHBondContact O-CA 3.37Å; S106-M114 WeakPolarHBondContact O-CB 3.43Å; I107-M114 HydrophobicContact CB-CB 4.41Å; I107-M114 HydrophobicContact CG1-CB 3.99Å; M114-T116 HydrophobicContact CE-CG2 4.26Å; M114-I125 CarbonylContact O-C 3.58Å; M114-I125 WeakPolarHBondContact O-CA 3.3Å; M114-F126 HydrophobicContact CG-CB 3.64Å; M114-F126 HydrophobicContact CG-CD2 4.02Å; M114-F126 HydrophobicContact CG-CG 4.19Å; M114-F126 PolarHBondContact N-O 3.17Å; M114-F126 PolarHBondContact O-N 3.4Å; M114-F126 HydrophobicContact SD-CB 4.28Å; M114-V128 HydrophobicContact CB-CG2 3.82Å; M114-V128 HydrophobicContact CG-CG2 3.72Å; M114-V128 HydrophobicContact SD-CG2 4.04Å
115Y97.9Very high95.8Very high0 Ų024 Ų240%012%0.119CC..EExtended strand (participates in β ladder)trans-125157.4166.768.6-108.5000111H104 L105 S106 M117 K124 I125 G146 S147 W148 F159H104-Y115 PolarHBondContact CD2-OH 2.94Å; L105-Y115 WeakPolarHBondContact CA-O 3.29Å; S106-Y115 VanDerWaalsContact CB-CZ 3.48Å; S106-Y115 WeakPolarHBondContact CB-OH 3.41Å; S106-Y115 PolarHBondContact N-O 3.44Å; S106-Y115 PolarHBondContact O-N 3.29Å; Y115-M117 HydrophobicContact CD2-CE 3.96Å; Y115-M117 HydrophobicContact CE2-CE 3.24Å; Y115-M117 HydrophobicContact CE2-CG 4.33Å; Y115-K124 CarbonylContact C-O 3.59Å; Y115-K124 WeakPolarHBondContact CA-O 3.36Å; Y115-I125 VanDerWaalsContact CB-CD1 3.45Å; Y115-G146 WeakPolarHBondContact OH-CA 3.37Å; Y115-G146 PolarHBondContact OH-O 3.35Å; Y115-G146 VanDerWaalsContact OH-O 3.05Å; Y115-S147 PolarHBondContact OH-N 3.09Å; Y115-S147 VanDerWaalsContact OH-N 3.16Å; Y115-W148 HydrophobicContact CD1-CD2 4.22Å; Y115-W148 AromaticContact CD1-CE2 3.49Å; Y115-W148 VanDerWaalsContact CD1-CE2 3.49Å; Y115-W148 HydrophobicContact CD1-CH2 4.36Å; Y115-W148 AromaticContact CD1-CZ2 3.58Å; Y115-W148 HydrophobicContact CD1-CZ2 3.58Å; Y115-W148 AromaticContact CD1-NE1 3.52Å; Y115-W148 AromaticContact CE1-CD1 3.92Å; Y115-W148 HydrophobicContact CE1-CD2 4.29Å; Y115-W148 AromaticContact CE1-CE2 3.88Å; Y115-W148 HydrophobicContact CE1-CG 4.35Å; Y115-W148 HydrophobicContact CE1-CZ2 4.42Å; Y115-W148 AromaticContact CE1-NE1 3.6Å; Y115-W148 HydrophobicContact CG-CZ2 4.4Å; Y115-F159 HydrophobicContact CD1-CB 4.33Å; Y115-F159 HydrophobicContact CD1-CD2 4.01Å; Y115-F159 HydrophobicContact CD1-CG 4.18Å; Y115-F159 HydrophobicContact CE1-CB 4.09Å; Y115-F159 HydrophobicContact CE1-CD2 4.08Å; Y115-F159 HydrophobicContact CE1-CG 4.31Å
116T97.8Very high95.8Very high0 Ų023.4 Ų23.40%012%0.116CC..EExtended strand (participates in β ladder)trans-123.4139162.460.10000109.1V78 H98 L105 M114 I123 K124 F126V78-T116 HydrophobicContact CG2-CG2 4.1Å; H98-T116 PolarHBondContact NE2-OG1 2.93Å; L105-T116 HydrophobicContact CB-CG2 4.36Å; L105-T116 HydrophobicContact CD1-CG2 3.81Å; L105-T116 HydrophobicContact CG-CG2 3.96Å; M114-T116 HydrophobicContact CE-CG2 4.26Å; T116-I123 CarbonylContact O-C 3.51Å; T116-I123 VanDerWaalsContact O-CA 3.3Å; T116-I123 WeakPolarHBondContact O-CA 3.34Å; T116-K124 PolarHBondContact N-O 2.75Å; T116-K124 PolarHBondContact O-N 2.78Å; T116-F126 HydrophobicContact CG2-CE2 4.16Å
117M96.6Very high95.7Very high0 Ų024.1 Ų24.10%012%0.118CC..EExtended strand (participates in β ladder)trans-125.6150.417558.517180.900110.1I102 T103 H104 Y115 S122 I123 P143 V161I102-M117 CarbonylContact C-O 3.57Å; I102-M117 WeakPolarHBondContact CA-O 3.35Å; T103-M117 PolarHBondContact N-O 3.06Å; T103-M117 WeakPolarHBondContact OG1-CG 3.48Å; T103-M117 PolarHBondContact OG1-O 3.39Å; H104-M117 HydrophobicContact CB-CE 4.06Å; H104-M117 HydrophobicContact CB-CG 3.43Å; H104-M117 VanDerWaalsContact CB-CG 3.43Å; H104-M117 HydrophobicContact CB-SD 3.47Å; H104-M117 WeakPolarHBondContact CB-SD 3.45Å; H104-M117 PolarHBondContact N-O 3.41Å; H104-M117 WeakPolarHBondContact O-CG 3.32Å; H104-M117 PolarHBondContact O-N 3.37Å; Y115-M117 HydrophobicContact CD2-CE 3.96Å; Y115-M117 HydrophobicContact CE2-CE 3.24Å; Y115-M117 HydrophobicContact CE2-CG 4.33Å; M117-S122 WeakPolarHBondContact CA-O 3.5Å; M117-I123 HydrophobicContact CB-CG1 4.01Å; M117-P143 HydrophobicContact CB-CB 4.15Å; M117-P143 HydrophobicContact CB-CG 3.83Å; M117-P143 HydrophobicContact CG-CB 4.46Å; M117-P143 HydrophobicContact CG-CG 4.46Å; M117-P143 HydrophobicContact SD-CB 3.79Å; M117-P143 HydrophobicContact SD-CG 4.4Å; M117-V161 HydrophobicContact CE-CG1 4.31Å; M117-V161 HydrophobicContact CE-CG2 4.28Å
118S95.1Very high95.4Very high0 Ų022.9 Ų22.90%011%0.112CC..EExtended strand (participates in β ladder)trans-145.2159.4-172.5174.50000113.2H98 G100 L101 D120 R121 S122 P143H98-S118 WeakPolarHBondContact ND1-CB 3.29Å; G100-S118 PolarHBondContact O-OG 3.19Å; L101-S118 VanDerWaalsContact O-CA 3.26Å; L101-S118 WeakPolarHBondContact O-CA 3.43Å; L101-S118 WeakPolarHBondContact O-CB 3.4Å; L101-S118 PolarHBondContact O-OG 3.25Å; S118-D120 WeakPolarHBondContact CB-OD1 3.28Å; S118-D120 PolarHBondContact O-N 3.24Å; S118-D120 VanDerWaalsContact O-N 3.09Å; S118-D120 PolarHBondContact OG-N 3.2Å; S118-R121 PolarHBondContact O-N 2.99Å; S118-R121 VanDerWaalsContact O-N 3.09Å; S118-S122 PolarHBondContact N-O 3.37Å; S118-P143 VanDerWaalsContact O-CD 3.27Å; S118-P143 WeakPolarHBondContact O-CD 3.44Å; S118-P143 WeakPolarHBondContact O-CG 3.27Å
119C94Very high95.1Very high45 Ų4524.8 Ų24.830%0.30413%0.125SC..THydrogen-bonded Turntrans-61.9-10.1170.568.70000114.2L101 T103 R121 V142L101-C119 PolarHBondContact N-SG 3.42Å; L101-C119 PolarHBondContact O-N 3.1Å; T103-C119 HydrophobicContact CG2-CB 4.35Å; C119-R121 PolarHBondContact O-N 3.19Å; C119-V142 HydrophobicContact CB-CG1 4.25Å
120D94Very high94.9Very high52 Ų5225.5 Ų25.528%0.27814%0.135SC..THydrogen-bonded Turntrans-73.95.4169.673.210.1000114.4H98 A99 S118 S122H98-D120 WeakPolarHBondContact CA-OD2 3.08Å; H98-D120 VanDerWaalsContact CB-OD2 3.29Å; H98-D120 WeakPolarHBondContact CB-OD2 3.2Å; H98-D120 IonicContact CG-OD2 2.78Å; H98-D120 IonicContact ND1-OD1 3.4Å; H98-D120 PolarHBondContact ND1-OD1 2.85Å; H98-D120 IonicContact ND1-OD2 2.74Å; H98-D120 PolarHBondContact ND1-OD2 2.9Å; H98-D120 VanDerWaalsContact ND1-OD2 3.07Å; A99-D120 PolarHBondContact N-OD2 3.39Å; S118-D120 WeakPolarHBondContact CB-OD1 3.28Å; S118-D120 PolarHBondContact O-N 3.24Å; S118-D120 VanDerWaalsContact O-N 3.09Å; S118-D120 PolarHBondContact OG-N 3.2Å; D120-S122 VanDerWaalsContact C-N 3.34Å; D120-S122 WeakPolarHBondContact OD1-CB 3.3Å; D120-S122 PolarHBondContact OD1-N 2.96Å; D120-S122 PolarHBondContact OD1-OG 2.9Å; D120-S122 PolarHBondContact OD2-OG 2.93Å
121R95.9Very high94.7Very high125 Ų12525.3 Ų25.347%0.47213%0.132SC..THydrogen-bonded Turntrans6337.6-179.8-47.4-174.1-171.6-172.13.7112.8S118 C119 L139 D140 Y141 V142S118-R121 PolarHBondContact O-N 2.99Å; S118-R121 VanDerWaalsContact O-N 3.09Å; C119-R121 PolarHBondContact O-N 3.19Å; R121-L139 HydrophobicContact CB-CB 4.43Å; R121-L139 WeakPolarHBondContact CB-O 3.21Å; R121-L139 PolarHBondContact O-N 3.27Å; R121-D140 PolarHBondContact NH1-O 2.7Å; R121-D140 VanDerWaalsContact NH1-O 3.09Å; R121-Y141 WeakPolarHBondContact CB-O 3.36Å; R121-Y141 WeakPolarHBondContact CG-O 3.28Å; R121-V142 HydrophobicContact CG-CG2 3.84Å
122S95Very high94.5Very high11 Ų1129 Ų298%0.07715%0.151CC..EExtended strand (participates in β ladder)trans-130.2151.9172.572.80000112.6H98 M117 S118 D120 F137H98-S122 PolarHBondContact CE1-OG 3.25Å; H98-S122 PolarHBondContact ND1-OG 2.97Å; H98-S122 VanDerWaalsContact ND1-OG 3.08Å; M117-S122 WeakPolarHBondContact CA-O 3.5Å; S118-S122 PolarHBondContact N-O 3.37Å; D120-S122 VanDerWaalsContact C-N 3.34Å; D120-S122 WeakPolarHBondContact OD1-CB 3.3Å; D120-S122 PolarHBondContact OD1-N 2.96Å; D120-S122 PolarHBondContact OD1-OG 2.9Å; D120-S122 PolarHBondContact OD2-OG 2.93Å; S122-F137 CarbonylContact C-O 3.44Å; S122-F137 VanDerWaalsContact CA-O 3.23Å; S122-F137 WeakPolarHBondContact CA-O 3.48Å; S122-F137 WeakPolarHBondContact CB-O 3.43Å
123I97Very high94.4Very high0 Ų030.8 Ų30.80%016%0.157CC..EExtended strand (participates in β ladder)trans-119.2136.9168.8-57.4-173.1000107.3T116 M117 I125 M136 F137 L139 F159 V161T116-I123 CarbonylContact O-C 3.51Å; T116-I123 VanDerWaalsContact O-CA 3.3Å; T116-I123 WeakPolarHBondContact O-CA 3.34Å; M117-I123 HydrophobicContact CB-CG1 4.01Å; I123-I125 HydrophobicContact CG2-CD1 3.83Å; I123-M136 CarbonylContact O-C 3.55Å; I123-M136 WeakPolarHBondContact O-CA 3.35Å; I123-F137 HydrophobicContact CB-CB 4.32Å; I123-F137 HydrophobicContact CB-CD2 4.18Å; I123-F137 HydrophobicContact CG2-CD2 4.24Å; I123-F137 PolarHBondContact N-O 3.31Å; I123-F137 PolarHBondContact O-N 3.48Å; I123-L139 HydrophobicContact CD1-CD1 3.85Å; I123-L139 HydrophobicContact CD1-CD2 4.38Å; I123-L139 HydrophobicContact CD1-CG 4.48Å; I123-L139 HydrophobicContact CG1-CD1 3.77Å; I123-L139 HydrophobicContact CG1-CG 4.29Å; I123-F159 HydrophobicContact CD1-CE2 3.84Å; I123-F159 HydrophobicContact CD1-CZ 4.44Å; I123-F159 HydrophobicContact CG2-CE2 4.13Å; I123-F159 HydrophobicContact CG2-CZ 4.23Å; I123-V161 HydrophobicContact CD1-CB 4.49Å; I123-V161 HydrophobicContact CD1-CG1 4.14Å; I123-V161 HydrophobicContact CD1-CG2 3.58Å
124K97.1Very high94.2Very high19 Ų1934.1 Ų34.18%0.08318%0.175CC..EExtended strand (participates in β ladder)trans-123.2130.3175.4-62.6-177-169.7-41.80109.1C97 Y115 T116 F126 M133 M136C97-K124 VanDerWaalsContact C-CE 3.41Å; C97-K124 HydrophobicContact CB-CD 4.01Å; C97-K124 WeakPolarHBondContact O-CE 3.38Å; Y115-K124 CarbonylContact C-O 3.59Å; Y115-K124 WeakPolarHBondContact CA-O 3.36Å; T116-K124 PolarHBondContact N-O 2.75Å; T116-K124 PolarHBondContact O-N 2.78Å; K124-F126 HydrophobicContact CB-CE2 3.6Å; K124-F126 HydrophobicContact CB-CZ 3.87Å; K124-F126 HydrophobicContact CD-CZ 4.37Å; K124-M133 HydrophobicContact CB-CG 4.41Å; K124-M133 HydrophobicContact CB-SD 4.1Å; K124-M133 HydrophobicContact CD-SD 3.68Å; K124-M133 HydrophobicContact CG-SD 4.01Å; K124-M136 HydrophobicContact CD-CE 4.34Å; K124-M136 HydrophobicContact CG-CE 4.37Å; K124-M136 HydrophobicContact CG-CG 4.08Å; K124-M136 PolarHBondContact NZ-SD 3.01Å
125I97.5Very high94.1Very high0 Ų036.1 Ų36.10%019%0.185CC..EExtended strand (participates in β ladder)trans-104.7134.3179.6-49.7-56.2000108.2M114 Y115 I123 M133 I134 N135 F137 F159 A174M114-I125 CarbonylContact O-C 3.58Å; M114-I125 WeakPolarHBondContact O-CA 3.3Å; Y115-I125 VanDerWaalsContact CB-CD1 3.45Å; I123-I125 HydrophobicContact CG2-CD1 3.83Å; I125-M133 CarbonylContact O-C 3.5Å; I125-M133 WeakPolarHBondContact O-CA 3.23Å; I125-I134 HydrophobicContact CB-CG1 4.15Å; I125-I134 HydrophobicContact CG2-CD1 3.9Å; I125-I134 HydrophobicContact CG2-CG1 3.77Å; I125-I134 PolarHBondContact O-N 2.84Å; I125-N135 HydrophobicContact CB-CB 3.93Å; I125-N135 HydrophobicContact CG1-CB 3.99Å; I125-N135 PolarHBondContact N-O 3.17Å; I125-N135 PolarHBondContact O-N 2.91Å; I125-F137 HydrophobicContact CD1-CE2 4.08Å; I125-F137 HydrophobicContact CG1-CD2 4.38Å; I125-F137 HydrophobicContact CG1-CE2 3.75Å; I125-F137 HydrophobicContact CG1-CZ 4.48Å; I125-F159 HydrophobicContact CD1-CE1 4.08Å; I125-F159 HydrophobicContact CD1-CZ 4.02Å; I125-A174 HydrophobicContact CD1-CB 4.32Å; I125-A174 HydrophobicContact CG1-CB 4.3Å; I125-A174 HydrophobicContact CG2-CB 3.95Å
126F96.7Very high93.9Very high0 Ų040.5 Ų40.50%021%0.207CC..EExtended strand (participates in β ladder)trans-121.6142177.8-54.3-102.1000110.7F80 F95 C97 L113 M114 T116 K124 D132 M133F80-F126 HydrophobicContact CE2-CD1 4.31Å; F80-F126 HydrophobicContact CZ-CB 4.19Å; F80-F126 HydrophobicContact CZ-CD1 4.13Å; F80-F126 HydrophobicContact CZ-CG 4.18Å; F95-F126 HydrophobicContact CD1-CE1 4.38Å; F95-F126 HydrophobicContact CD2-CE1 4.22Å; F95-F126 HydrophobicContact CE2-CD1 4.5Å; F95-F126 HydrophobicContact CE2-CE1 4.39Å; F95-F126 HydrophobicContact CG-CE1 4.19Å; C97-F126 WeakPolarHBondContact SG-CZ 3.29Å; L113-F126 WeakPolarHBondContact CA-O 3.35Å; M114-F126 HydrophobicContact CG-CB 3.64Å; M114-F126 HydrophobicContact CG-CD2 4.02Å; M114-F126 HydrophobicContact CG-CG 4.19Å; M114-F126 PolarHBondContact N-O 3.17Å; M114-F126 PolarHBondContact O-N 3.4Å; M114-F126 HydrophobicContact SD-CB 4.28Å; T116-F126 HydrophobicContact CG2-CE2 4.16Å; K124-F126 HydrophobicContact CB-CE2 3.6Å; K124-F126 HydrophobicContact CB-CZ 3.87Å; K124-F126 HydrophobicContact CD-CZ 4.37Å; F126-D132 CarbonylContact C-O 3.59Å; F126-D132 WeakPolarHBondContact CA-O 3.3Å; F126-M133 HydrophobicContact CD1-CB 3.8Å; F126-M133 HydrophobicContact CD1-CG 4.35Å; F126-M133 HydrophobicContact CE1-CB 3.67Å; F126-M133 HydrophobicContact CE1-CG 4.03Å; F126-M133 HydrophobicContact CZ-CB 4.38Å; F126-M133 HydrophobicContact CZ-CG 4.25Å; F126-M133 HydrophobicContact CZ-SD 4.5Å
127D94Very high93.5Very high35 Ų3540.8 Ų40.819%0.18721%0.208CC..EExtended strand (participates in β ladder)trans-80.2114.8156-175.4-36.8000107.9C129 N130 F131 D132 I134D127-C129 PolarHBondContact OD1-N 2.87Å; D127-N130 HydrophobicContact CB-CB 4.27Å; D127-N130 VanDerWaalsContact CG-ND2 3.33Å; D127-N130 PolarHBondContact OD1-N 2.91Å; D127-N130 PolarHBondContact OD1-ND2 3.33Å; D127-N130 PolarHBondContact OD2-ND2 3.22Å; D127-F131 WeakPolarHBondContact O-CA 3.32Å; D127-F131 PolarHBondContact O-N 3.22Å; D127-D132 PolarHBondContact N-O 2.82Å; D127-D132 PolarHBondContact O-N 3.01Å; D127-I134 HydrophobicContact CB-CG2 3.69Å
128V92.5Very high93.4Very high0 Ų051.9 Ų51.90%025%0.25CS..THydrogen-bonded Turntrans-70.4-38.3-173.8178.20000111.2F68 I70 I107 G111 T112 M114 F131F68-V128 HydrophobicContact CB-CG1 3.9Å; F68-V128 HydrophobicContact CD2-CG1 3.88Å; F68-V128 HydrophobicContact CG-CG1 4.17Å; I70-V128 HydrophobicContact CD1-CG1 4.26Å; I107-V128 HydrophobicContact CG2-CG2 4.47Å; G111-V128 WeakPolarHBondContact O-CB 3.45Å; T112-V128 PolarHBondContact O-N 3.03Å; M114-V128 HydrophobicContact CB-CG2 3.82Å; M114-V128 HydrophobicContact CG-CG2 3.72Å; M114-V128 HydrophobicContact SD-CG2 4.04Å; V128-F131 WeakPolarHBondContact O-CD1 3.12Å; V128-F131 VanDerWaalsContact O-CE1 3.28Å; V128-F131 WeakPolarHBondContact O-CE1 3.36Å
129C90Very high93.4Very high47 Ų4752.4 Ų52.432%0.31825%0.253SS..THydrogen-bonded Turntrans-75.8-35.2-175.1-63.40000112D127 F131D127-C129 PolarHBondContact OD1-N 2.87Å; C129-F131 WeakPolarHBondContact O-CZ 3.48Å
130N89.5Confident93.3Very high100 Ų10055.4 Ų55.454%0.53527%0.266SS..THydrogen-bonded Turntrans-92.1-3.8179.2-63.9-44.6000113.1D127 D132D127-N130 HydrophobicContact CB-CB 4.27Å; D127-N130 VanDerWaalsContact CG-ND2 3.33Å; D127-N130 PolarHBondContact OD1-N 2.91Å; D127-N130 PolarHBondContact OD1-ND2 3.33Å; D127-N130 PolarHBondContact OD2-ND2 3.22Å; N130-D132 PolarHBondContact O-N 3.33Å
131F87.3Confident93.4Very high47 Ų4754 Ų5421%0.20626%0.257CS..THydrogen-bonded Turntrans57.135.1-178.7-38.6-59.1000113.4F68 F80 V92 K93 F95 D127 V128 C129F68-F131 AromaticContact CD1-CE1 3.55Å; F68-F131 HydrophobicContact CD1-CE1 3.55Å; F68-F131 HydrophobicContact CD1-CZ 4.16Å; F68-F131 HydrophobicContact CD2-CE1 4.31Å; F68-F131 HydrophobicContact CE1-CD1 4.4Å; F68-F131 AromaticContact CE1-CE1 3.11Å; F68-F131 HydrophobicContact CE1-CE1 3.11Å; F68-F131 AromaticContact CE1-CZ 3.26Å; F68-F131 HydrophobicContact CE1-CZ 3.26Å; F68-F131 AromaticContact CE2-CE1 3.92Å; F68-F131 HydrophobicContact CE2-CE1 3.92Å; F68-F131 HydrophobicContact CE2-CZ 4.18Å; F68-F131 HydrophobicContact CG-CE1 4.15Å; F68-F131 AromaticContact CZ-CE1 3.33Å; F68-F131 HydrophobicContact CZ-CE1 3.33Å; F68-F131 AromaticContact CZ-CZ 3.27Å; F68-F131 HydrophobicContact CZ-CZ 3.27Å; F80-F131 HydrophobicContact CD1-CD1 4.27Å; V92-F131 HydrophobicContact CG1-CD1 3.78Å; V92-F131 HydrophobicContact CG1-CD2 3.64Å; V92-F131 HydrophobicContact CG1-CE1 3.83Å; V92-F131 HydrophobicContact CG1-CE2 3.65Å; V92-F131 HydrophobicContact CG1-CG 3.69Å; V92-F131 HydrophobicContact CG1-CZ 3.74Å; K93-F131 HydrophobicContact CB-CB 4.43Å; K93-F131 HydrophobicContact CD-CB 3.75Å; K93-F131 VanDerWaalsContact CD-O 3.27Å; K93-F131 WeakPolarHBondContact CD-O 3.12Å; K93-F131 WeakPolarHBondContact CE-O 3.34Å; K93-F131 PolarHBondContact NZ-O 3.29Å; F95-F131 VanDerWaalsContact CZ-O 3.25Å; F95-F131 WeakPolarHBondContact CZ-O 3.37Å; D127-F131 WeakPolarHBondContact O-CA 3.32Å; D127-F131 PolarHBondContact O-N 3.22Å; V128-F131 WeakPolarHBondContact O-CD1 3.12Å; V128-F131 VanDerWaalsContact O-CE1 3.28Å; V128-F131 WeakPolarHBondContact O-CE1 3.36Å; C129-F131 WeakPolarHBondContact O-CZ 3.48Å
132D88.2Confident93.4Very high78 Ų7849.4 Ų49.442%0.41724%0.243SC..EExtended strand (participates in β ladder)trans-122.3137.5-172.3-79.4-22.8000111.5K93 F126 D127 N130 I134K93-D132 IonicContact NZ-OD1 3.08Å; K93-D132 PolarHBondContact NZ-OD1 3.39Å; F126-D132 CarbonylContact C-O 3.59Å; F126-D132 WeakPolarHBondContact CA-O 3.3Å; D127-D132 PolarHBondContact N-O 2.82Å; D127-D132 PolarHBondContact O-N 3.01Å; N130-D132 PolarHBondContact O-N 3.33Å; D132-I134 PolarHBondContact O-N 3.16Å
133M91.7Very high93.5Very high81 Ų8148.9 Ų48.940%0.39924%0.239SC..EExtended strand (participates in β ladder)trans-76.6106.4169.2-176.1-178.167.200108K124 I125 F126 M136K124-M133 HydrophobicContact CB-CG 4.41Å; K124-M133 HydrophobicContact CB-SD 4.1Å; K124-M133 HydrophobicContact CD-SD 3.68Å; K124-M133 HydrophobicContact CG-SD 4.01Å; I125-M133 CarbonylContact O-C 3.5Å; I125-M133 WeakPolarHBondContact O-CA 3.23Å; F126-M133 HydrophobicContact CD1-CB 3.8Å; F126-M133 HydrophobicContact CD1-CG 4.35Å; F126-M133 HydrophobicContact CE1-CB 3.67Å; F126-M133 HydrophobicContact CE1-CG 4.03Å; F126-M133 HydrophobicContact CZ-CB 4.38Å; F126-M133 HydrophobicContact CZ-CG 4.25Å; F126-M133 HydrophobicContact CZ-SD 4.5Å; M133-M136 HydrophobicContact CE-CE 3.48Å; M133-M136 VanDerWaalsContact CE-CE 3.48Å; M133-M136 HydrophobicContact SD-CE 3.63Å
134I93Very high93.4Very high77 Ų7749.9 Ų49.940%0.39525%0.246SC..EExtended strand (participates in β ladder)trans-90.7-22.5-174.261.1169.9000113.1L113 I125 D127 D132L113-I134 HydrophobicContact CD2-CD1 3.66Å; I125-I134 HydrophobicContact CB-CG1 4.15Å; I125-I134 HydrophobicContact CG2-CD1 3.9Å; I125-I134 HydrophobicContact CG2-CG1 3.77Å; I125-I134 PolarHBondContact O-N 2.84Å; D127-I134 HydrophobicContact CB-CG2 3.69Å; D132-I134 PolarHBondContact O-N 3.16Å
135N94.7Very high93.4Very high42 Ų4249.3 Ų49.323%0.22524%0.244CC..EExtended strand (participates in β ladder)trans-152.6158.3180-150.3-9.3000111.9I125 F137 A174 G176I125-N135 HydrophobicContact CB-CB 3.93Å; I125-N135 HydrophobicContact CG1-CB 3.99Å; I125-N135 PolarHBondContact N-O 3.17Å; I125-N135 PolarHBondContact O-N 2.91Å; N135-F137 HydrophobicContact CB-CZ 4.38Å; N135-F137 VanDerWaalsContact ND2-CE1 3.31Å; N135-F137 WeakPolarHBondContact ND2-CE1 3.35Å; N135-F137 WeakPolarHBondContact ND2-CZ 3.21Å; N135-A174 WeakPolarHBondContact CB-O 3.36Å; N135-A174 PolarHBondContact ND2-O 3.41Å; N135-G176 PolarHBondContact ND2-O 3.1Å
136M94.7Very high93.4Very high91 Ų9149.3 Ų49.345%0.44824%0.244SC..EExtended strand (participates in β ladder)trans-147.3130.8175.7-178.4-176.2-42.900110.3I123 K124 M133I123-M136 CarbonylContact O-C 3.55Å; I123-M136 WeakPolarHBondContact O-CA 3.35Å; K124-M136 HydrophobicContact CD-CE 4.34Å; K124-M136 HydrophobicContact CG-CE 4.37Å; K124-M136 HydrophobicContact CG-CG 4.08Å; K124-M136 PolarHBondContact NZ-SD 3.01Å; M133-M136 HydrophobicContact CE-CE 3.48Å; M133-M136 VanDerWaalsContact CE-CE 3.48Å; M133-M136 HydrophobicContact SD-CE 3.63Å
137F89.6Confident93.4Very high6 Ų649.3 Ų49.33%0.02624%0.244CC..EExtended strand (participates in β ladder)trans-113.2140175.8-50.7-57.1000110S122 I123 I125 N135 F159 D173 G176 G178S122-F137 CarbonylContact C-O 3.44Å; S122-F137 VanDerWaalsContact CA-O 3.23Å; S122-F137 WeakPolarHBondContact CA-O 3.48Å; S122-F137 WeakPolarHBondContact CB-O 3.43Å; I123-F137 HydrophobicContact CB-CB 4.32Å; I123-F137 HydrophobicContact CB-CD2 4.18Å; I123-F137 HydrophobicContact CG2-CD2 4.24Å; I123-F137 PolarHBondContact N-O 3.31Å; I123-F137 PolarHBondContact O-N 3.48Å; I125-F137 HydrophobicContact CD1-CE2 4.08Å; I125-F137 HydrophobicContact CG1-CD2 4.38Å; I125-F137 HydrophobicContact CG1-CE2 3.75Å; I125-F137 HydrophobicContact CG1-CZ 4.48Å; N135-F137 HydrophobicContact CB-CZ 4.38Å; N135-F137 VanDerWaalsContact ND2-CE1 3.31Å; N135-F137 WeakPolarHBondContact ND2-CE1 3.35Å; N135-F137 WeakPolarHBondContact ND2-CZ 3.21Å; F137-F159 HydrophobicContact CD2-CZ 4.09Å; F137-F159 HydrophobicContact CE2-CE1 4.09Å; F137-F159 AromaticContact CE2-CZ 3.83Å; F137-F159 HydrophobicContact CE2-CZ 3.83Å; F137-D173 WeakPolarHBondContact CZ-O 3.46Å; F137-G176 WeakPolarHBondContact CE1-O 3.06Å; F137-G178 VanDerWaalsContact CE1-N 3.3Å
138R93.8Very high93.6Very high234 Ų23447.7 Ų47.788%0.88324%0.235SC*.EExtended strand (participates in β ladder)trans-104.9126.1167.3-173.8175-176.6139.50.9107.9
139L94.3Very high93.8Very high11 Ų1147.7 Ų47.76%0.05824%0.236CC..  trans-97.5151.3-179.6-56.3175.1000109.9R121 I123 Y141 P143 Y172R121-L139 HydrophobicContact CB-CB 4.43Å; R121-L139 WeakPolarHBondContact CB-O 3.21Å; R121-L139 PolarHBondContact O-N 3.27Å; I123-L139 HydrophobicContact CD1-CD1 3.85Å; I123-L139 HydrophobicContact CD1-CD2 4.38Å; I123-L139 HydrophobicContact CD1-CG 4.48Å; I123-L139 HydrophobicContact CG1-CD1 3.77Å; I123-L139 HydrophobicContact CG1-CG 4.29Å; L139-Y141 VanDerWaalsContact C-N 3.3Å; L139-Y141 HydrophobicContact CB-CD1 4.39Å; L139-Y141 HydrophobicContact CB-CE1 4.3Å; L139-Y141 WeakPolarHBondContact CB-O 3.47Å; L139-Y141 HydrophobicContact CD1-CD2 4.35Å; L139-Y141 HydrophobicContact CD1-CE2 3.79Å; L139-Y141 HydrophobicContact CD2-CE1 4.19Å; L139-P143 HydrophobicContact CD1-CB 3.86Å; L139-P143 HydrophobicContact CD1-CG 3.8Å; L139-Y172 HydrophobicContact CD2-CE2 4.46Å
140D93.9Very high94.1Very high108 Ų10846 Ų4658%0.57822%0.223SC*.SBendtrans-78.4-17.716954.7-25.8000112.2R121 R170R121-D140 PolarHBondContact NH1-O 2.7Å; R121-D140 VanDerWaalsContact NH1-O 3.09Å; D140-R170 IonicContact OD1-NH1 3.52Å; D140-R170 IonicContact OD2-NH1 3.58Å; D140-R170 IonicContact OD2-NH2 3.94Å
141Y95.3Very high94.3Very high21 Ų2142.3 Ų42.38%0.08220%0.203CC..SBendtrans-118.9172.4178.962.1-91.4000113.2R121 L139 P143 V161 E163 Y172R121-Y141 WeakPolarHBondContact CB-O 3.36Å; R121-Y141 WeakPolarHBondContact CG-O 3.28Å; L139-Y141 VanDerWaalsContact C-N 3.3Å; L139-Y141 HydrophobicContact CB-CD1 4.39Å; L139-Y141 HydrophobicContact CB-CE1 4.3Å; L139-Y141 WeakPolarHBondContact CB-O 3.47Å; L139-Y141 HydrophobicContact CD1-CD2 4.35Å; L139-Y141 HydrophobicContact CD1-CE2 3.79Å; L139-Y141 HydrophobicContact CD2-CE1 4.19Å; Y141-P143 HydrophobicContact CE2-CB 4.33Å; Y141-V161 HydrophobicContact CE2-CG1 4.04Å; Y141-E163 HydrophobicContact CD1-CG 4.14Å; Y141-E163 HydrophobicContact CD2-CB 3.91Å; Y141-E163 HydrophobicContact CD2-CG 3.6Å; Y141-E163 HydrophobicContact CE1-CG 4.17Å; Y141-E163 HydrophobicContact CE2-CB 4.22Å; Y141-E163 HydrophobicContact CE2-CG 3.59Å; Y141-E163 HydrophobicContact CG-CB 4.36Å; Y141-E163 HydrophobicContact CG-CG 3.88Å; Y141-Y172 WeakPolarHBondContact OH-CE2 3.25Å; Y141-Y172 PolarHBondContact OH-OH 3.39Å
142V96.2Very high94.4Very high30 Ų3043.1 Ų43.118%0.18221%0.213CC..  trans-90.6120.6172171.70000109.4C119 R121 R164C119-V142 HydrophobicContact CB-CG1 4.25Å; R121-V142 HydrophobicContact CG-CG2 3.84Å; V142-R164 HydrophobicContact CB-CB 4.1Å; V142-R164 HydrophobicContact CG1-CB 4.04Å; V142-R164 WeakPolarHBondContact O-CB 3.27Å; V142-R164 PolarHBondContact O-N 2.87Å
143P96.8Very high94.5Very high0 Ų044.1 Ų44.10%023%0.232CC..EExtended strand (participates in β ladder)trans-74.9133.8178.131.3-35.3000111.3T103 M117 S118 L139 Y141 V161T103-P143 WeakPolarHBondContact CB-O 3.47Å; T103-P143 WeakPolarHBondContact CG2-O 3.49Å; T103-P143 PolarHBondContact OG1-O 2.96Å; M117-P143 HydrophobicContact CB-CB 4.15Å; M117-P143 HydrophobicContact CB-CG 3.83Å; M117-P143 HydrophobicContact CG-CB 4.46Å; M117-P143 HydrophobicContact CG-CG 4.46Å; M117-P143 HydrophobicContact SD-CB 3.79Å; M117-P143 HydrophobicContact SD-CG 4.4Å; S118-P143 VanDerWaalsContact O-CD 3.27Å; S118-P143 WeakPolarHBondContact O-CD 3.44Å; S118-P143 WeakPolarHBondContact O-CG 3.27Å; L139-P143 HydrophobicContact CD1-CB 3.86Å; L139-P143 HydrophobicContact CD1-CG 3.8Å; Y141-P143 HydrophobicContact CE2-CB 4.33Å; P143-V161 HydrophobicContact CB-CG1 3.64Å
144S94.9Very high94.5Very high21 Ų2142.4 Ų42.415%0.14722%0.224CC..EExtended strand (participates in β ladder)trans-91.9-58.4-179.6-169.10000112.1A162 E191S144-A162 PolarHBondContact N-O 3.09Å; S144-E191 VanDerWaalsContact CB-OE1 3.25Å; S144-E191 WeakPolarHBondContact CB-OE1 3.35Å; S144-E191 PolarHBondContact OG-OE1 2.89Å
145T96.9Very high94.3Very high7 Ų743.8 Ų43.84%0.04325%0.247CC..EExtended strand (participates in β ladder)trans-146.6174.3-179.5-165.10000110.6V161 A162 V192 C193 I195T145-V161 WeakPolarHBondContact O-CA 3.39Å; T145-A162 HydrophobicContact CG2-CB 3.64Å; T145-A162 PolarHBondContact O-N 2.74Å; T145-V192 HydrophobicContact CG2-CG1 4.49Å; T145-C193 VanDerWaalsContact CB-O 3.32Å; T145-C193 WeakPolarHBondContact CB-O 3.49Å; T145-C193 WeakPolarHBondContact CG2-O 3.24Å; T145-C193 PolarHBondContact OG1-O 3.47Å; T145-I195 HydrophobicContact CG2-CD1 4.43Å; T145-I195 HydrophobicContact CG2-CG1 4.12Å
146G96.9Very high94.2Very high0 Ų044.2 Ų44.20%025%0.251CS..EExtended strand (participates in β ladder)trans-166.6176.2173.400000114.2H104 Y115 A160H104-G146 PolarHBondContact CD2-N 2.65Å; H104-G146 PolarHBondContact CD2-O 2.87Å; H104-G146 VanDerWaalsContact CD2-O 3.22Å; H104-G146 PolarHBondContact NE2-O 3.47Å; Y115-G146 WeakPolarHBondContact OH-CA 3.37Å; Y115-G146 PolarHBondContact OH-O 3.35Å; Y115-G146 VanDerWaalsContact OH-O 3.05Å; G146-A160 CarbonylContact C-O 3.46Å; G146-A160 WeakPolarHBondContact CA-O 3.39Å
147S97.9Very high94.3Very high0 Ų040.3 Ų40.30%023%0.233CC..EExtended strand (participates in β ladder)trans-152.9146.8172.5-176.90000110.6Y115 F159 A160 I195Y115-S147 PolarHBondContact OH-N 3.09Å; Y115-S147 VanDerWaalsContact OH-N 3.16Å; S147-F159 CarbonylContact O-C 3.51Å; S147-F159 VanDerWaalsContact O-CA 3.28Å; S147-F159 WeakPolarHBondContact O-CA 3.32Å; S147-F159 WeakPolarHBondContact O-CB 3.31Å; S147-A160 PolarHBondContact N-O 2.85Å; S147-A160 PolarHBondContact O-N 3.32Å; S147-I195 WeakPolarHBondContact CB-O 3.46Å
148W98Very high94.6Very high0 Ų040 Ų400%023%0.232CC..EExtended strand (participates in β ladder)trans-63.7137.1160.2-64.798.7000109.1S106 N108 L113 Y115 H150 A157 F159 A174 Y197S106-W148 PolarHBondContact O-NE1 2.81Å; N108-W148 VanDerWaalsContact CA-CD1 3.46Å; N108-W148 HydrophobicContact CB-CB 4.22Å; N108-W148 HydrophobicContact CB-CD2 3.65Å; N108-W148 HydrophobicContact CB-CE3 4.18Å; N108-W148 HydrophobicContact CB-CG 3.66Å; N108-W148 VanDerWaalsContact N-CD1 3.31Å; L113-W148 HydrophobicContact CB-CH2 3.78Å; L113-W148 HydrophobicContact CB-CZ2 3.87Å; L113-W148 HydrophobicContact CD1-CH2 4.17Å; L113-W148 HydrophobicContact CD1-CZ3 4.33Å; Y115-W148 HydrophobicContact CD1-CD2 4.22Å; Y115-W148 AromaticContact CD1-CE2 3.49Å; Y115-W148 VanDerWaalsContact CD1-CE2 3.49Å; Y115-W148 HydrophobicContact CD1-CH2 4.36Å; Y115-W148 AromaticContact CD1-CZ2 3.58Å; Y115-W148 HydrophobicContact CD1-CZ2 3.58Å; Y115-W148 AromaticContact CD1-NE1 3.52Å; Y115-W148 AromaticContact CE1-CD1 3.92Å; Y115-W148 HydrophobicContact CE1-CD2 4.29Å; Y115-W148 AromaticContact CE1-CE2 3.88Å; Y115-W148 HydrophobicContact CE1-CG 4.35Å; Y115-W148 HydrophobicContact CE1-CZ2 4.42Å; Y115-W148 AromaticContact CE1-NE1 3.6Å; Y115-W148 HydrophobicContact CG-CZ2 4.4Å; W148-H150 AromaticContact CE3-CD2 3.67Å; W148-H150 AromaticContact CE3-NE2 3.62Å; W148-A157 HydrophobicContact CZ3-CB 4.25Å; W148-F159 HydrophobicContact CD2-CB 4.12Å; W148-F159 HydrophobicContact CE3-CB 3.77Å; W148-F159 HydrophobicContact CE3-CD1 4.48Å; W148-F159 HydrophobicContact CE3-CG 4.48Å; W148-F159 HydrophobicContact CH2-CD1 4.47Å; W148-F159 HydrophobicContact CZ3-CB 4.19Å; W148-F159 HydrophobicContact CZ3-CD1 4.05Å; W148-F159 HydrophobicContact CZ3-CG 4.43Å; W148-A174 HydrophobicContact CH2-CB 3.56Å; W148-A174 HydrophobicContact CZ3-CB 3.59Å; W148-Y197 WeakPolarHBondContact O-CB 3.35Å
149I97Very high94.8Very high1 Ų128.9 Ų28.91%0.00519%0.19CC..  trans-132.939.4-17658.3157.6000111.6A158 A160 I171 Y197 A204 W216I149-A158 HydrophobicContact CD1-CB 4.37Å; I149-A158 HydrophobicContact CG1-CB 3.94Å; I149-A158 PolarHBondContact N-O 3.08Å; I149-A160 HydrophobicContact CD1-CB 4.4Å; I149-A160 HydrophobicContact CG2-CB 4.12Å; I149-I171 HydrophobicContact CD1-CD1 3.72Å; I149-I171 HydrophobicContact CD1-CG1 4.28Å; I149-I171 HydrophobicContact CD1-CG2 3.81Å; I149-Y197 HydrophobicContact CB-CD2 3.89Å; I149-Y197 HydrophobicContact CB-CE2 4.18Å; I149-Y197 HydrophobicContact CB-CG 4.34Å; I149-Y197 HydrophobicContact CG2-CD2 3.93Å; I149-Y197 HydrophobicContact CG2-CG 4.33Å; I149-A204 HydrophobicContact CG2-CB 4.12Å; I149-W216 HydrophobicContact CD1-CH2 3.98Å; I149-W216 HydrophobicContact CD1-CZ3 3.78Å; I149-W216 HydrophobicContact CG2-CH2 4.04Å
150H95.7Very high95Very high11 Ų1128.3 Ų28.35%0.05119%0.187CC..  trans-137.3152.7-17979.894.6000110.8W148 D154 V156 A158 Y199W148-H150 AromaticContact CE3-CD2 3.67Å; W148-H150 AromaticContact CE3-NE2 3.62Å; H150-D154 HydrophobicContact CB-CB 4.37Å; H150-V156 WeakPolarHBondContact CB-O 3.22Å; H150-A158 HydrophobicContact CB-CB 4.35Å; H150-A158 PolarHBondContact CD2-O 2.6Å; H150-Y199 VanDerWaalsContact O-CE1 3.27Å; H150-Y199 WeakPolarHBondContact O-CE1 3.34Å
151N93.8Very high95.2Very high23 Ų2323.2 Ų23.212%0.12316%0.16CC..  trans-86.6157.3167.6-79.7-54.8000111.4A153 D154 E202N151-A153 PolarHBondContact O-N 3.3Å; N151-A153 VanDerWaalsContact O-N 3.11Å; N151-D154 PolarHBondContact N-OD2 3.11Å; N151-D154 WeakPolarHBondContact O-CB 3.22Å; N151-D154 PolarHBondContact O-N 3.29Å; N151-E202 WeakPolarHBondContact ND2-CG 3.42Å; N151-E202 PolarHBondContact ND2-OE1 3.2Å
152P89Confident95.4Very high64 Ų6422.2 Ų22.242%0.41616%0.156SC..THydrogen-bonded Turntrans-57.8-26.5-180-27.635.5000115.2Y109 N110Y109-P152 HydrophobicContact CD1-CG 3.69Å; Y109-P152 HydrophobicContact CE1-CG 4.49Å; N110-P152 HydrophobicContact CB-CB 4.31Å; N110-P152 HydrophobicContact CB-CG 4.02Å
153A89.7Confident95.4Very high98 Ų9821.5 Ų21.581%0.8115%0.151SC*.THydrogen-bonded Turntrans-88.2-7.4179.700000113.4N151N151-A153 PolarHBondContact O-N 3.3Å; N151-A153 VanDerWaalsContact O-N 3.11Å
154D92.5Very high95.3Very high45 Ų4525.8 Ų25.824%0.24117%0.167CC..SBendtrans-73.3143.4-179.5-64.2-18.7000110.2H150 N151 V156H150-D154 HydrophobicContact CB-CB 4.37Å; N151-D154 PolarHBondContact N-OD2 3.11Å; N151-D154 WeakPolarHBondContact O-CB 3.22Å; N151-D154 PolarHBondContact O-N 3.29Å; D154-V156 VanDerWaalsContact C-N 3.28Å; D154-V156 PolarHBondContact O-N 2.64Å
155A89.2Confident95.2Very high106 Ų10632 Ų3288%0.87620%0.199SC*.SBendtrans-68.1-28.5-178.100000113.2
156V93Very high95.1Very high51 Ų5133.1 Ų33.131%0.30921%0.206SC..SBendtrans-106.4125.5-177.3-178.50000108.9H150 D154 A158 D173 L181H150-V156 WeakPolarHBondContact CB-O 3.22Å; D154-V156 VanDerWaalsContact C-N 3.28Å; D154-V156 PolarHBondContact O-N 2.64Å; V156-A158 HydrophobicContact CG1-CB 4.08Å; V156-A158 PolarHBondContact O-N 2.94Å; V156-D173 HydrophobicContact CG1-CB 3.85Å; V156-L181 HydrophobicContact CG1-CD1 3.76Å
157A95.2Very high95.1Very high9 Ų935 Ų357%0.07422%0.218CC..  trans-82.968.4174.400000109.3L113 W148 D173 A174L113-A157 HydrophobicContact CD1-CB 3.81Å; W148-A157 HydrophobicContact CZ3-CB 4.25Å; A157-D173 PolarHBondContact N-OD1 2.85Å; A157-A174 HydrophobicContact CB-CB 3.95Å; A157-A174 WeakPolarHBondContact O-CB 3.29Å; A157-A174 PolarHBondContact O-N 3.43Å
158A97.4Very high95Very high0 Ų035.9 Ų35.90%022%0.224CC..EExtended strand (participates in β ladder)trans-75.1137.3-171.900000112.3I149 H150 V156 I171 Y172 P219I149-A158 HydrophobicContact CD1-CB 4.37Å; I149-A158 HydrophobicContact CG1-CB 3.94Å; I149-A158 PolarHBondContact N-O 3.08Å; H150-A158 HydrophobicContact CB-CB 4.35Å; H150-A158 PolarHBondContact CD2-O 2.6Å; V156-A158 HydrophobicContact CG1-CB 4.08Å; V156-A158 PolarHBondContact O-N 2.94Å; A158-I171 HydrophobicContact CB-CG2 4.31Å; A158-Y172 CarbonylContact C-O 3.56Å; A158-Y172 VanDerWaalsContact CA-O 3.29Å; A158-Y172 WeakPolarHBondContact CA-O 3.25Å; A158-P219 HydrophobicContact CB-CG 3.69Å
159F97.8Very high95Very high0 Ų035.9 Ų35.90%022%0.224CC..EExtended strand (participates in β ladder)trans-138.8144.5171.467.8-79.2000111Y115 I123 I125 F137 S147 W148 V161 I171 Y172 A174Y115-F159 HydrophobicContact CD1-CB 4.33Å; Y115-F159 HydrophobicContact CD1-CD2 4.01Å; Y115-F159 HydrophobicContact CD1-CG 4.18Å; Y115-F159 HydrophobicContact CE1-CB 4.09Å; Y115-F159 HydrophobicContact CE1-CD2 4.08Å; Y115-F159 HydrophobicContact CE1-CG 4.31Å; I123-F159 HydrophobicContact CD1-CE2 3.84Å; I123-F159 HydrophobicContact CD1-CZ 4.44Å; I123-F159 HydrophobicContact CG2-CE2 4.13Å; I123-F159 HydrophobicContact CG2-CZ 4.23Å; I125-F159 HydrophobicContact CD1-CE1 4.08Å; I125-F159 HydrophobicContact CD1-CZ 4.02Å; F137-F159 HydrophobicContact CD2-CZ 4.09Å; F137-F159 HydrophobicContact CE2-CE1 4.09Å; F137-F159 AromaticContact CE2-CZ 3.83Å; F137-F159 HydrophobicContact CE2-CZ 3.83Å; S147-F159 CarbonylContact O-C 3.51Å; S147-F159 VanDerWaalsContact O-CA 3.28Å; S147-F159 WeakPolarHBondContact O-CA 3.32Å; S147-F159 WeakPolarHBondContact O-CB 3.31Å; W148-F159 HydrophobicContact CD2-CB 4.12Å; W148-F159 HydrophobicContact CE3-CB 3.77Å; W148-F159 HydrophobicContact CE3-CD1 4.48Å; W148-F159 HydrophobicContact CE3-CG 4.48Å; W148-F159 HydrophobicContact CH2-CD1 4.47Å; W148-F159 HydrophobicContact CZ3-CB 4.19Å; W148-F159 HydrophobicContact CZ3-CD1 4.05Å; W148-F159 HydrophobicContact CZ3-CG 4.43Å; F159-V161 HydrophobicContact CD2-CG2 3.68Å; F159-V161 HydrophobicContact CE2-CG2 3.51Å; F159-I171 WeakPolarHBondContact O-CA 3.31Å; F159-Y172 WeakPolarHBondContact CD1-O 3.37Å; F159-Y172 HydrophobicContact CE2-CD2 4.2Å; F159-Y172 HydrophobicContact CE2-CG 4.5Å; F159-Y172 VanDerWaalsContact CZ-CB 3.49Å; F159-Y172 HydrophobicContact CZ-CD2 4.33Å; F159-Y172 HydrophobicContact CZ-CG 4.18Å; F159-Y172 PolarHBondContact N-O 2.54Å; F159-Y172 PolarHBondContact O-N 3.35Å; F159-A174 HydrophobicContact CD1-CB 4.1Å; F159-A174 HydrophobicContact CE1-CB 4.04Å
160A98.3Very high95.1Very high0 Ų038.1 Ų38.10%023%0.233CC..EExtended strand (participates in β ladder)trans-95.7142.8179.500000110.5G146 S147 I149 I169 R170 I171 I195 W216G146-A160 CarbonylContact C-O 3.46Å; G146-A160 WeakPolarHBondContact CA-O 3.39Å; S147-A160 PolarHBondContact N-O 2.85Å; S147-A160 PolarHBondContact O-N 3.32Å; I149-A160 HydrophobicContact CD1-CB 4.4Å; I149-A160 HydrophobicContact CG2-CB 4.12Å; A160-I169 HydrophobicContact CB-CG2 4.01Å; A160-R170 CarbonylContact C-O 3.57Å; A160-R170 WeakPolarHBondContact CA-O 3.34Å; A160-I171 HydrophobicContact CB-CD1 3.5Å; A160-I195 HydrophobicContact CB-CD1 4.11Å; A160-I195 HydrophobicContact CB-CG2 4.43Å; A160-W216 HydrophobicContact CB-CH2 3.75Å; A160-W216 HydrophobicContact CB-CZ2 4.28Å
161V98.3Very high95.2Very high0 Ų037.6 Ų37.60%023%0.23CC..EExtended strand (participates in β ladder)trans-133.6119178.7-176.70000108.4M117 I123 Y141 P143 T145 F159 I169 R170 Y172M117-V161 HydrophobicContact CE-CG1 4.31Å; M117-V161 HydrophobicContact CE-CG2 4.28Å; I123-V161 HydrophobicContact CD1-CB 4.49Å; I123-V161 HydrophobicContact CD1-CG1 4.14Å; I123-V161 HydrophobicContact CD1-CG2 3.58Å; Y141-V161 HydrophobicContact CE2-CG1 4.04Å; P143-V161 HydrophobicContact CB-CG1 3.64Å; T145-V161 WeakPolarHBondContact O-CA 3.39Å; F159-V161 HydrophobicContact CD2-CG2 3.68Å; F159-V161 HydrophobicContact CE2-CG2 3.51Å; V161-I169 WeakPolarHBondContact O-CA 3.47Å; V161-R170 PolarHBondContact N-O 3.46Å; V161-R170 PolarHBondContact O-N 2.99Å; V161-Y172 HydrophobicContact CB-CD2 4.3Å; V161-Y172 HydrophobicContact CB-CE2 4.03Å; V161-Y172 HydrophobicContact CG2-CD2 3.74Å; V161-Y172 HydrophobicContact CG2-CE2 3.9Å
162A98Very high95.4Very high0 Ų036.7 Ų36.70%023%0.225CC..EExtended strand (participates in β ladder)trans-80.1139.6169.600000110.5S144 T145 V192 I195S144-A162 PolarHBondContact N-O 3.09Å; T145-A162 HydrophobicContact CG2-CB 3.64Å; T145-A162 PolarHBondContact O-N 2.74Å; A162-V192 HydrophobicContact CB-CB 3.77Å; A162-V192 HydrophobicContact CB-CG1 4.1Å; A162-V192 WeakPolarHBondContact CB-O 3.21Å; A162-I195 HydrophobicContact CB-CD1 4.29Å
163E96.3Very high95.7Very high16 Ų1635.3 Ų35.38%0.07521%0.214CC..EExtended strand (participates in β ladder)trans-84.8139.5174.4-57.9-173.9179.500110.9Y141 S166 S168 R170Y141-E163 HydrophobicContact CD1-CG 4.14Å; Y141-E163 HydrophobicContact CD2-CB 3.91Å; Y141-E163 HydrophobicContact CD2-CG 3.6Å; Y141-E163 HydrophobicContact CE1-CG 4.17Å; Y141-E163 HydrophobicContact CE2-CB 4.22Å; Y141-E163 HydrophobicContact CE2-CG 3.59Å; Y141-E163 HydrophobicContact CG-CB 4.36Å; Y141-E163 HydrophobicContact CG-CG 3.88Å; E163-S166 VanDerWaalsContact OE2-CB 3.31Å; E163-S166 WeakPolarHBondContact OE2-CB 3.39Å; E163-S166 PolarHBondContact OE2-OG 2.73Å; E163-S168 PolarHBondContact N-O 2.85Å; E163-S168 VanDerWaalsContact N-O 3.1Å; E163-R170 IonicContact OE1-CZ 3.46Å; E163-R170 IonicContact OE1-NE 2.73Å; E163-R170 PolarHBondContact OE1-NE 3.26Å; E163-R170 IonicContact OE1-NH2 3.57Å; E163-R170 PolarHBondContact OE1-NH2 2.97Å
164R94.8Very high96Very high90 Ų9030.6 Ų30.634%0.3418%0.175SC..THydrogen-bonded Turntrans-71.8146.1169.7-173.3178.7-69.4-175.1-2.9110.5T103 V142 S166T103-R164 VanDerWaalsContact CG2-NH2 3.34Å; V142-R164 HydrophobicContact CB-CB 4.1Å; V142-R164 HydrophobicContact CG1-CB 4.04Å; V142-R164 WeakPolarHBondContact O-CB 3.27Å; V142-R164 PolarHBondContact O-N 2.87Å; R164-S166 PolarHBondContact O-N 2.62Å; R164-S166 VanDerWaalsContact O-N 3.11Å
165D93.3Very high96Very high151 Ų15136.7 Ų36.781%0.80720%0.195SC*.THydrogen-bonded Turntrans58.120.3179.4-55.5-53.2000113.8E191D165-E191 PolarHBondContact N-OE2 3.21Å
166S94.9Very high96.2Very high30 Ų3032.9 Ų32.921%0.2117%0.166CC..SBendtrans-145.3154-174.2167.80000109.4E163 R164 S168 E191E163-S166 VanDerWaalsContact OE2-CB 3.31Å; E163-S166 WeakPolarHBondContact OE2-CB 3.39Å; E163-S166 PolarHBondContact OE2-OG 2.73Å; R164-S166 PolarHBondContact O-N 2.62Å; R164-S166 VanDerWaalsContact O-N 3.11Å; S166-S168 VanDerWaalsContact C-N 3.29Å; S166-S168 WeakPolarHBondContact OG-CB 3.47Å; S166-S168 PolarHBondContact OG-N 2.96Å; S166-S168 PolarHBondContact OG-OG 3.01Å; S166-E191 VanDerWaalsContact O-CA 3.25Å; S166-E191 WeakPolarHBondContact O-CA 3.48Å
167V96.4Very high96Very high41 Ų4135.5 Ų35.525%0.24819%0.187CC..SBendtrans-88.6-2.1178.5-62.90000112.5E185 H188V167-E185 WeakPolarHBondContact CG2-O 3.36Å; V167-H188 VanDerWaalsContact CB-O 3.32Å; V167-H188 WeakPolarHBondContact CB-O 3.37Å; V167-H188 WeakPolarHBondContact CG1-O 3.38Å
168S97.2Very high95.7Very high18 Ų1836 Ų3613%0.12619%0.193CC..  trans-82.2143.6-168.5-60.20000112.8E163 S166 F184E163-S168 PolarHBondContact N-O 2.85Å; E163-S168 VanDerWaalsContact N-O 3.1Å; S166-S168 VanDerWaalsContact C-N 3.29Å; S166-S168 WeakPolarHBondContact OG-CB 3.47Å; S166-S168 PolarHBondContact OG-N 2.96Å; S166-S168 PolarHBondContact OG-OG 3.01Å; S168-F184 WeakPolarHBondContact CA-O 3.33Å
169I98.1Very high95.5Very high0 Ų043 Ų430%023%0.225CC..EExtended strand (participates in β ladder)trans-118.3126168-58.4160.3000108A160 V161 I171 F184 V192 I195A160-I169 HydrophobicContact CB-CG2 4.01Å; V161-I169 WeakPolarHBondContact O-CA 3.47Å; I169-I171 HydrophobicContact CG2-CD1 4.1Å; I169-F184 HydrophobicContact CB-CB 4.2Å; I169-F184 HydrophobicContact CB-CD2 4.12Å; I169-F184 HydrophobicContact CG2-CD2 4.32Å; I169-F184 PolarHBondContact N-O 3.04Å; I169-F184 PolarHBondContact O-N 2.78Å; I169-V192 HydrophobicContact CD1-CG1 4.29Å; I169-V192 HydrophobicContact CD1-CG2 3.97Å; I169-V192 HydrophobicContact CG1-CB 4.31Å; I169-V192 HydrophobicContact CG1-CG1 4.42Å; I169-V192 HydrophobicContact CG1-CG2 3.97Å; I169-I195 HydrophobicContact CD1-CD1 4.37Å; I169-I195 HydrophobicContact CG1-CD1 4.32Å; I169-I195 HydrophobicContact CG2-CD1 4.02Å
170R97.8Very high95.4Very high47 Ų4745 Ų4518%0.17724%0.238CC..EExtended strand (participates in β ladder)trans-107.9138.6175.6-59.8-160.9-172.9-178.713.6111.1D140 A160 V161 E163 Y172 P180 V183D140-R170 IonicContact OD1-NH1 3.52Å; D140-R170 IonicContact OD2-NH1 3.58Å; D140-R170 IonicContact OD2-NH2 3.94Å; A160-R170 CarbonylContact C-O 3.57Å; A160-R170 WeakPolarHBondContact CA-O 3.34Å; V161-R170 PolarHBondContact N-O 3.46Å; V161-R170 PolarHBondContact O-N 2.99Å; E163-R170 IonicContact OE1-CZ 3.46Å; E163-R170 IonicContact OE1-NE 2.73Å; E163-R170 PolarHBondContact OE1-NE 3.26Å; E163-R170 IonicContact OE1-NH2 3.57Å; E163-R170 PolarHBondContact OE1-NH2 2.97Å; R170-Y172 HydrophobicContact CB-CD2 4.37Å; R170-Y172 HydrophobicContact CB-CE2 3.54Å; R170-Y172 VanDerWaalsContact CD-OH 3.31Å; R170-Y172 WeakPolarHBondContact CD-OH 3.43Å; R170-P180 HydrophobicContact CB-CB 4.28Å; R170-V183 HydrophobicContact CG-CG1 4.12Å; R170-V183 HydrophobicContact CG-CG2 3.98Å
171I97.9Very high95.3Very high0 Ų048.9 Ų48.90%026%0.259CS..EExtended strand (participates in β ladder)trans-104.6131.6178.3-51.4-50.2000109I149 A158 F159 A160 I169 P180 L181 H182 F184 W216 Y223I149-I171 HydrophobicContact CD1-CD1 3.72Å; I149-I171 HydrophobicContact CD1-CG1 4.28Å; I149-I171 HydrophobicContact CD1-CG2 3.81Å; A158-I171 HydrophobicContact CB-CG2 4.31Å; F159-I171 WeakPolarHBondContact O-CA 3.31Å; A160-I171 HydrophobicContact CB-CD1 3.5Å; I169-I171 HydrophobicContact CG2-CD1 4.1Å; I171-P180 CarbonylContact O-C 3.58Å; I171-P180 VanDerWaalsContact O-CA 3.25Å; I171-P180 WeakPolarHBondContact O-CA 3.37Å; I171-L181 HydrophobicContact CG2-CB 4.45Å; I171-L181 HydrophobicContact CG2-CD1 4.37Å; I171-L181 PolarHBondContact O-N 2.91Å; I171-H182 HydrophobicContact CB-CB 4.23Å; I171-H182 HydrophobicContact CG1-CB 4.16Å; I171-H182 PolarHBondContact N-O 3.14Å; I171-F184 HydrophobicContact CD1-CD2 4.49Å; I171-F184 HydrophobicContact CD1-CE2 4.17Å; I171-F184 HydrophobicContact CG1-CE2 4.17Å; I171-W216 HydrophobicContact CD1-CH2 3.79Å; I171-W216 HydrophobicContact CD1-CZ3 3.97Å; I171-Y223 HydrophobicContact CB-CE1 4.38Å; I171-Y223 HydrophobicContact CG1-CD1 4.44Å; I171-Y223 HydrophobicContact CG1-CE1 3.97Å; I171-Y223 HydrophobicContact CG2-CE1 4.19Å
172Y97.5Very high95.2Very high5 Ų552 Ų522%0.0227%0.273CS..EExtended strand (participates in β ladder)trans-125.7157178.7-62-85.9000110.8L139 Y141 A158 F159 V161 R170 G178 P180L139-Y172 HydrophobicContact CD2-CE2 4.46Å; Y141-Y172 WeakPolarHBondContact OH-CE2 3.25Å; Y141-Y172 PolarHBondContact OH-OH 3.39Å; A158-Y172 CarbonylContact C-O 3.56Å; A158-Y172 VanDerWaalsContact CA-O 3.29Å; A158-Y172 WeakPolarHBondContact CA-O 3.25Å; F159-Y172 WeakPolarHBondContact CD1-O 3.37Å; F159-Y172 HydrophobicContact CE2-CD2 4.2Å; F159-Y172 HydrophobicContact CE2-CG 4.5Å; F159-Y172 VanDerWaalsContact CZ-CB 3.49Å; F159-Y172 HydrophobicContact CZ-CD2 4.33Å; F159-Y172 HydrophobicContact CZ-CG 4.18Å; F159-Y172 PolarHBondContact N-O 2.54Å; F159-Y172 PolarHBondContact O-N 3.35Å; V161-Y172 HydrophobicContact CB-CD2 4.3Å; V161-Y172 HydrophobicContact CB-CE2 4.03Å; V161-Y172 HydrophobicContact CG2-CD2 3.74Å; V161-Y172 HydrophobicContact CG2-CE2 3.9Å; R170-Y172 HydrophobicContact CB-CD2 4.37Å; R170-Y172 HydrophobicContact CB-CE2 3.54Å; R170-Y172 VanDerWaalsContact CD-OH 3.31Å; R170-Y172 WeakPolarHBondContact CD-OH 3.43Å; Y172-G178 VanDerWaalsContact CE1-O 3.3Å; Y172-G178 WeakPolarHBondContact CE1-O 3.4Å; Y172-P180 HydrophobicContact CD1-CB 4.31Å; Y172-P180 HydrophobicContact CE1-CB 3.87Å; Y172-P180 HydrophobicContact CE1-CG 4.48Å
173D96.4Very high95.2Very high34 Ų3454.3 Ų54.318%0.18229%0.287CS..EExtended strand (participates in β ladder)trans-93.5127.5163.2-178.34.1000109.3F137 V156 A157 R175 G176 L181F137-D173 WeakPolarHBondContact CZ-O 3.46Å; V156-D173 HydrophobicContact CG1-CB 3.85Å; A157-D173 PolarHBondContact N-OD1 2.85Å; D173-R175 PolarHBondContact O-N 3.39Å; D173-R175 VanDerWaalsContact O-N 3.16Å; D173-R175 PolarHBondContact OD1-N 3.17Å; D173-G176 PolarHBondContact O-N 3.45Å; D173-L181 HydrophobicContact CB-CD1 4.1Å; D173-L181 HydrophobicContact CB-CD2 4.45Å; D173-L181 HydrophobicContact CB-CG 4.5Å
174A95.3Very high95.3Very high0 Ų054.3 Ų54.30%029%0.287CS..THydrogen-bonded Turntrans-58.9-26.1176.900000113.8I125 N135 W148 A157 F159I125-A174 HydrophobicContact CD1-CB 4.32Å; I125-A174 HydrophobicContact CG1-CB 4.3Å; I125-A174 HydrophobicContact CG2-CB 3.95Å; N135-A174 WeakPolarHBondContact CB-O 3.36Å; N135-A174 PolarHBondContact ND2-O 3.41Å; W148-A174 HydrophobicContact CH2-CB 3.56Å; W148-A174 HydrophobicContact CZ3-CB 3.59Å; A157-A174 HydrophobicContact CB-CB 3.95Å; A157-A174 WeakPolarHBondContact O-CB 3.29Å; A157-A174 PolarHBondContact O-N 3.43Å; F159-A174 HydrophobicContact CD1-CB 4.1Å; F159-A174 HydrophobicContact CE1-CB 4.04Å
175R93.7Very high95.2Very high173 Ų17356.3 Ų56.365%0.65330%0.3SS*.THydrogen-bonded Turntrans-103.46176.2-61.5179-177.9161.1-0.9113.2D173D173-R175 PolarHBondContact O-N 3.39Å; D173-R175 VanDerWaalsContact O-N 3.16Å; D173-R175 PolarHBondContact OD1-N 3.17Å
176G91.8Very high95.2Very high25 Ų2557.9 Ų57.926%0.25830%0.3SS..SBendtrans-79.9-173.7-179.600000113.7N135 F137 D173 G178N135-G176 PolarHBondContact ND2-O 3.1Å; F137-G176 WeakPolarHBondContact CE1-O 3.06Å; D173-G176 PolarHBondContact O-N 3.45Å; G176-G178 VanDerWaalsContact C-N 3.33Å
177S89Confident95Very high107 Ų10758.9 Ų58.975%0.74830%0.302SS*.  trans-79.3-9.6179.856.40000114.7
178G89.1Confident95.1Very high20 Ų2057.3 Ų57.321%0.20629%0.292CS..SBendtrans94.6-0.4-17200000114.6F137 Y172 G176F137-G178 VanDerWaalsContact CE1-N 3.3Å; Y172-G178 VanDerWaalsContact CE1-O 3.3Å; Y172-G178 WeakPolarHBondContact CE1-O 3.4Å; G176-G178 VanDerWaalsContact C-N 3.33Å
179E93.8Very high95Very high145 Ų14560.2 Ų60.268%0.67831%0.31SS*.  trans-77138.8167-66.9-61.4147.200110.2L181E179-L181 PolarHBondContact O-N 3.26Å
180P95.5Very high94.9Very high43 Ų4365.7 Ų65.728%0.27933%0.334SS..  trans-68.5131.9178.528.2-33.3000110.9R170 I171 Y172 H182 V183R170-P180 HydrophobicContact CB-CB 4.28Å; I171-P180 CarbonylContact O-C 3.58Å; I171-P180 VanDerWaalsContact O-CA 3.25Å; I171-P180 WeakPolarHBondContact O-CA 3.37Å; Y172-P180 HydrophobicContact CD1-CB 4.31Å; Y172-P180 HydrophobicContact CE1-CB 3.87Å; Y172-P180 HydrophobicContact CE1-CG 4.48Å; P180-H182 VanDerWaalsContact C-N 3.3Å; P180-V183 HydrophobicContact CB-CG2 3.98Å; P180-V183 HydrophobicContact CG-CG2 4.04Å
181L96Very high94.8Very high82 Ų8264.2 Ų64.243%0.42933%0.329SS..SBendtrans-67.6-33171.5-58.5179.6000112V156 I171 D173 E179V156-L181 HydrophobicContact CG1-CD1 3.76Å; I171-L181 HydrophobicContact CG2-CB 4.45Å; I171-L181 HydrophobicContact CG2-CD1 4.37Å; I171-L181 PolarHBondContact O-N 2.91Å; D173-L181 HydrophobicContact CB-CD1 4.1Å; D173-L181 HydrophobicContact CB-CD2 4.45Å; D173-L181 HydrophobicContact CB-CG 4.5Å; E179-L181 PolarHBondContact O-N 3.26Å
182H97.2Very high94.8Very high65 Ų6564.2 Ų64.230%0.30133%0.329SS..EExtended strand (participates in β ladder)trans-158.3153.3-179.4-169.268.6000110.6I171 P180 F184 Y223I171-H182 HydrophobicContact CB-CB 4.23Å; I171-H182 HydrophobicContact CG1-CB 4.16Å; I171-H182 PolarHBondContact N-O 3.14Å; P180-H182 VanDerWaalsContact C-N 3.3Å; H182-F184 AromaticContact CD2-CD2 3.97Å; H182-F184 AromaticContact CD2-CE2 3.87Å; H182-F184 AromaticContact CD2-CZ 3.97Å; H182-F184 AromaticContact NE2-CD1 3.92Å; H182-F184 AromaticContact NE2-CE1 3.89Å; H182-Y223 HydrophobicContact CB-CD1 4.41Å; H182-Y223 HydrophobicContact CB-CD2 3.93Å; H182-Y223 HydrophobicContact CB-CE1 3.99Å; H182-Y223 HydrophobicContact CB-CE2 3.46Å; H182-Y223 VanDerWaalsContact CB-CE2 3.46Å; H182-Y223 HydrophobicContact CB-CG 4.37Å; H182-Y223 VanDerWaalsContact CB-CZ 3.47Å; H182-Y223 AromaticContact CD2-CD2 3.73Å; H182-Y223 AromaticContact CD2-CG 3.65Å; H182-Y223 AromaticContact CG-CD2 3.52Å; H182-Y223 AromaticContact CG-CE2 3.59Å; H182-Y223 AromaticContact CG-CG 3.9Å; H182-Y223 AromaticContact ND1-CD2 3.73Å; H182-Y223 AromaticContact ND1-CE2 3.93Å
183V97.4Very high94.7Very high49 Ų4965.2 Ų65.230%0.29734%0.336SS..EExtended strand (participates in β ladder)trans-134.2119.8177.5-177.60000109R170 P180 E185R170-V183 HydrophobicContact CG-CG1 4.12Å; R170-V183 HydrophobicContact CG-CG2 3.98Å; P180-V183 HydrophobicContact CB-CG2 3.98Å; P180-V183 HydrophobicContact CG-CG2 4.04Å; V183-E185 HydrophobicContact CG1-CG 4.11Å
184F97.3Very high94.8Very high16 Ų1664.3 Ų64.37%0.0733%0.332CS..EExtended strand (participates in β ladder)trans-88108.1167.7-66.7-78.8000109S168 I169 I171 H182 M187 W216 Y223S168-F184 WeakPolarHBondContact CA-O 3.33Å; I169-F184 HydrophobicContact CB-CB 4.2Å; I169-F184 HydrophobicContact CB-CD2 4.12Å; I169-F184 HydrophobicContact CG2-CD2 4.32Å; I169-F184 PolarHBondContact N-O 3.04Å; I169-F184 PolarHBondContact O-N 2.78Å; I171-F184 HydrophobicContact CD1-CD2 4.49Å; I171-F184 HydrophobicContact CD1-CE2 4.17Å; I171-F184 HydrophobicContact CG1-CE2 4.17Å; H182-F184 AromaticContact CD2-CD2 3.97Å; H182-F184 AromaticContact CD2-CE2 3.87Å; H182-F184 AromaticContact CD2-CZ 3.97Å; H182-F184 AromaticContact NE2-CD1 3.92Å; H182-F184 AromaticContact NE2-CE1 3.89Å; F184-M187 HydrophobicContact CB-CB 4.36Å; F184-M187 HydrophobicContact CB-CG 3.59Å; F184-M187 HydrophobicContact CD1-CG 3.4Å; F184-M187 HydrophobicContact CD1-SD 3.92Å; F184-M187 HydrophobicContact CE1-CG 4.21Å; F184-M187 HydrophobicContact CE1-SD 4.27Å; F184-M187 HydrophobicContact CG-CG 3.73Å; F184-W216 HydrophobicContact CE2-CD2 4.07Å; F184-W216 AromaticContact CE2-CE3 3.56Å; F184-W216 HydrophobicContact CE2-CE3 3.56Å; F184-W216 HydrophobicContact CE2-CH2 4.2Å; F184-W216 AromaticContact CE2-CZ3 3.65Å; F184-W216 HydrophobicContact CE2-CZ3 3.65Å; F184-W216 HydrophobicContact CZ-CB 4.46Å; F184-W216 AromaticContact CZ-CD2 3.95Å; F184-W216 HydrophobicContact CZ-CD2 3.95Å; F184-W216 AromaticContact CZ-CE3 3.49Å; F184-W216 HydrophobicContact CZ-CE3 3.49Å; F184-W216 VanDerWaalsContact CZ-CE3 3.49Å; F184-W216 HydrophobicContact CZ-CG 4.38Å; F184-W216 HydrophobicContact CZ-CZ3 4.04Å; F184-Y223 HydrophobicContact CE2-CD1 4.32Å; F184-Y223 HydrophobicContact CZ-CD1 4.12Å; F184-Y223 HydrophobicContact CZ-CG 4.19Å
185E94.7Very high94.9Very high132 Ų13264.4 Ų64.462%0.61733%0.332SS*.SBendtrans-87.3-22.6-176.8-64.2-174.4175.400114.4V167 V183V167-E185 WeakPolarHBondContact CG2-O 3.36Å; V183-E185 HydrophobicContact CG1-CG 4.11Å
186K91.9Very high95.1Very high183 Ų18358.1 Ų58.180%0.79631%0.31SS*.SBendtrans-144.930.2-168.5-63.7-175.2-177.2172.70114.1
187M92.1Very high95.4Very high52 Ų5257.3 Ų57.326%0.25630%0.299SS..SBendtrans-70.1-35.2177.8-77.1-68.3-70.900112.5F184 E214 W216F184-M187 HydrophobicContact CB-CB 4.36Å; F184-M187 HydrophobicContact CB-CG 3.59Å; F184-M187 HydrophobicContact CD1-CG 3.4Å; F184-M187 HydrophobicContact CD1-SD 3.92Å; F184-M187 HydrophobicContact CE1-CG 4.21Å; F184-M187 HydrophobicContact CE1-SD 4.27Å; F184-M187 HydrophobicContact CG-CG 3.73Å; M187-E214 HydrophobicContact CE-CB 4.25Å; M187-W216 HydrophobicContact CE-CB 3.97Å; M187-W216 HydrophobicContact CE-CG 4.14Å
188H96.5Very high95.8Very high8 Ų852.3 Ų52.34%0.03726%0.264CS..  trans-121.2152.8-178.2-72.4-89.8000111.5V167 K190 V192 S206 D208 M212 E214V167-H188 VanDerWaalsContact CB-O 3.32Å; V167-H188 WeakPolarHBondContact CB-O 3.37Å; V167-H188 WeakPolarHBondContact CG1-O 3.38Å; H188-K190 VanDerWaalsContact C-N 3.35Å; H188-K190 WeakPolarHBondContact CB-O 3.49Å; H188-V192 HydrophobicContact CB-CG2 3.89Å; H188-V192 WeakPolarHBondContact CD2-CG2 3.42Å; H188-S206 PolarHBondContact CE1-O 3.25Å; H188-S206 PolarHBondContact NE2-OG 2.84Å; H188-D208 HydrophobicContact CB-CB 4.03Å; H188-D208 IonicContact ND1-OD2 3.82Å; H188-M212 PolarHBondContact CE1-O 3.1Å; H188-M212 VanDerWaalsContact CE1-O 3.29Å; H188-M212 PolarHBondContact ND1-O 3.22Å; H188-E214 WeakPolarHBondContact CE1-CG 3.36Å; H188-E214 WeakPolarHBondContact NE2-CG 3.47Å
189P95.3Very high96.1Very high79 Ų7953.5 Ų53.551%0.51326%0.263SS..SBendtrans-78-18.6172.931.7-36.7000113.4D208 I210 M212P189-D208 WeakPolarHBondContact CD-OD2 3.17Å; P189-D208 VanDerWaalsContact CG-OD2 3.22Å; P189-D208 WeakPolarHBondContact CG-OD2 3.39Å; P189-I210 HydrophobicContact CG-CD1 3.75Å; P189-I210 HydrophobicContact CG-CG1 4.45Å; P189-M212 HydrophobicContact CG-CB 4.48Å
190K96Very high96.1Very high114 Ų11448.4 Ų48.450%0.49625%0.246SC..SBendtrans-136.6174.9-179.8-73.1-65.2-173.41770112.1H188 V192 D208 I210H188-K190 VanDerWaalsContact C-N 3.35Å; H188-K190 WeakPolarHBondContact CB-O 3.49Å; K190-V192 PolarHBondContact O-N 3.11Å; K190-D208 HydrophobicContact CB-CB 4.29Å; K190-D208 PolarHBondContact N-OD2 2.83Å; K190-I210 HydrophobicContact CB-CG1 4.35Å; K190-I210 HydrophobicContact CB-CG2 4.35Å; K190-I210 HydrophobicContact CG-CD1 4.25Å; K190-I210 HydrophobicContact CG-CG1 4.25Å; K190-I210 HydrophobicContact CG-CG2 3.82Å
191E95.8Very high96.2Very high17 Ų1748.4 Ų48.48%0.07924%0.241CC..  trans-55.5130.4178.2174-179155.400111.1S144 D165 S166 D208 Q209S144-E191 VanDerWaalsContact CB-OE1 3.25Å; S144-E191 WeakPolarHBondContact CB-OE1 3.35Å; S144-E191 PolarHBondContact OG-OE1 2.89Å; D165-E191 PolarHBondContact N-OE2 3.21Å; S166-E191 VanDerWaalsContact O-CA 3.25Å; S166-E191 WeakPolarHBondContact O-CA 3.48Å; E191-D208 CarbonylContact O-C 3.6Å; E191-D208 VanDerWaalsContact O-CA 3.27Å; E191-D208 WeakPolarHBondContact O-CA 3.35Å; E191-D208 WeakPolarHBondContact O-CB 3.32Å; E191-Q209 HydrophobicContact CB-CG 4.26Å; E191-Q209 WeakPolarHBondContact O-CG 3.46Å; E191-Q209 PolarHBondContact O-N 3.13Å; E191-Q209 PolarHBondContact OE1-NE2 3.12Å; E191-Q209 PolarHBondContact OE2-NE2 2.79Å; E191-Q209 VanDerWaalsContact OE2-NE2 3.15Å
192V97.9Very high96.2Very high0 Ų045.3 Ų45.30%023%0.225CC..EExtended strand (participates in β ladder)trans-77.7122.8177.8-179.80000109.2T145 A162 I169 H188 K190 I195T145-V192 HydrophobicContact CG2-CG1 4.49Å; A162-V192 HydrophobicContact CB-CB 3.77Å; A162-V192 HydrophobicContact CB-CG1 4.1Å; A162-V192 WeakPolarHBondContact CB-O 3.21Å; I169-V192 HydrophobicContact CD1-CG1 4.29Å; I169-V192 HydrophobicContact CD1-CG2 3.97Å; I169-V192 HydrophobicContact CG1-CB 4.31Å; I169-V192 HydrophobicContact CG1-CG1 4.42Å; I169-V192 HydrophobicContact CG1-CG2 3.97Å; H188-V192 HydrophobicContact CB-CG2 3.89Å; H188-V192 WeakPolarHBondContact CD2-CG2 3.42Å; K190-V192 PolarHBondContact O-N 3.11Å; V192-I195 HydrophobicContact CG1-CD1 4.1Å; V192-I195 HydrophobicContact CG1-CG1 3.75Å
193C96.2Very high96.2Very high25 Ų2542.2 Ų42.217%0.16921%0.21CC..EExtended strand (participates in β ladder)trans-111.1-18.5-176.8640000113.6T145 I207 D208 Q209T145-C193 VanDerWaalsContact CB-O 3.32Å; T145-C193 WeakPolarHBondContact CB-O 3.49Å; T145-C193 WeakPolarHBondContact CG2-O 3.24Å; T145-C193 PolarHBondContact OG1-O 3.47Å; C193-I207 PolarHBondContact N-O 3.49Å; C193-D208 VanDerWaalsContact SG-C 3.6Å; C193-Q209 HydrophobicContact CB-CG 4.06Å
194L98.2Very high96.2Very high16 Ų1639.9 Ų39.98%0.08420%0.196CC..EExtended strand (participates in β ladder)trans-134.3138.9174.8-60.7172.2000111.4S206 I207 P250 L253L194-S206 CarbonylContact O-C 3.57Å; L194-S206 VanDerWaalsContact O-CA 3.26Å; L194-S206 WeakPolarHBondContact O-CA 3.41Å; L194-I207 HydrophobicContact CB-CB 4.27Å; L194-I207 HydrophobicContact CB-CG1 4.46Å; L194-I207 HydrophobicContact CD1-CD1 4.32Å; L194-I207 PolarHBondContact N-O 3.46Å; L194-I207 VanDerWaalsContact N-O 3.09Å; L194-I207 PolarHBondContact O-N 3.1Å; L194-P250 HydrophobicContact CD1-CB 3.69Å; L194-P250 HydrophobicContact CD1-CG 4.17Å; L194-L253 HydrophobicContact CB-CB 4.22Å; L194-L253 HydrophobicContact CD1-CB 3.98Å
195I98.4Very high96.3Very high2 Ų239.1 Ų39.11%0.0119%0.193CC..EExtended strand (participates in β ladder)trans-139.2133.4167.9-52178.2000106.7T145 S147 A160 A162 I169 V192 I205 W216T145-I195 HydrophobicContact CG2-CD1 4.43Å; T145-I195 HydrophobicContact CG2-CG1 4.12Å; S147-I195 WeakPolarHBondContact CB-O 3.46Å; A160-I195 HydrophobicContact CB-CD1 4.11Å; A160-I195 HydrophobicContact CB-CG2 4.43Å; A162-I195 HydrophobicContact CB-CD1 4.29Å; I169-I195 HydrophobicContact CD1-CD1 4.37Å; I169-I195 HydrophobicContact CG1-CD1 4.32Å; I169-I195 HydrophobicContact CG2-CD1 4.02Å; V192-I195 HydrophobicContact CG1-CD1 4.1Å; V192-I195 HydrophobicContact CG1-CG1 3.75Å; I195-I205 CarbonylContact C-O 3.38Å; I195-I205 WeakPolarHBondContact CA-O 3.49Å; I195-W216 HydrophobicContact CG2-CZ2 4.02Å
196E98Very high96.4Very high41 Ų4132.8 Ų32.819%0.19216%0.163CC..EExtended strand (participates in β ladder)trans-141.3150.4169.5-76.5-64.9163.900110A204 I205 L253 I255 K327E196-A204 WeakPolarHBondContact O-CA 3.31Å; E196-I205 PolarHBondContact N-O 2.67Å; E196-I205 PolarHBondContact O-N 3.18Å; E196-L253 HydrophobicContact CB-CD2 3.73Å; E196-L253 HydrophobicContact CB-CG 3.89Å; E196-L253 HydrophobicContact CG-CB 4.11Å; E196-L253 HydrophobicContact CG-CD2 4.04Å; E196-L253 HydrophobicContact CG-CG 3.84Å; E196-L253 VanDerWaalsContact CG-O 3.29Å; E196-L253 WeakPolarHBondContact CG-O 3.38Å; E196-I255 HydrophobicContact CB-CD1 3.83Å; E196-I255 HydrophobicContact CB-CG1 4.22Å; E196-K327 IonicContact OE1-NZ 2.99Å
197Y97.8Very high96.8Very high7 Ų724.1 Ų24.13%0.02713%0.126CC..EExtended strand (participates in β ladder)trans-109.6123-176.6-170.9-109.7000112.5W148 I149 Y199 E202 A204W148-Y197 WeakPolarHBondContact O-CB 3.35Å; I149-Y197 HydrophobicContact CB-CD2 3.89Å; I149-Y197 HydrophobicContact CB-CE2 4.18Å; I149-Y197 HydrophobicContact CB-CG 4.34Å; I149-Y197 HydrophobicContact CG2-CD2 3.93Å; I149-Y197 HydrophobicContact CG2-CG 4.33Å; Y197-Y199 AromaticContact CD1-CD1 3.43Å; Y197-Y199 HydrophobicContact CD1-CD1 3.43Å; Y197-Y199 VanDerWaalsContact CD1-CD1 3.43Å; Y197-Y199 HydrophobicContact CD1-CD2 4.23Å; Y197-Y199 AromaticContact CD1-CE1 3.45Å; Y197-Y199 HydrophobicContact CD1-CE1 3.45Å; Y197-Y199 VanDerWaalsContact CD1-CE1 3.45Å; Y197-Y199 HydrophobicContact CD1-CE2 4.27Å; Y197-Y199 AromaticContact CD1-CG 3.83Å; Y197-Y199 HydrophobicContact CD1-CG 3.83Å; Y197-Y199 AromaticContact CD1-CZ 3.9Å; Y197-Y199 AromaticContact CE1-CD1 3.72Å; Y197-Y199 HydrophobicContact CE1-CD1 3.72Å; Y197-Y199 HydrophobicContact CE1-CE1 4.03Å; Y197-Y199 HydrophobicContact CE1-CG 4.28Å; Y197-Y199 HydrophobicContact CG-CE1 4.5Å; Y197-Y199 WeakPolarHBondContact O-CD2 3.49Å; Y197-Y199 VanDerWaalsContact O-CE2 3.26Å; Y197-Y199 WeakPolarHBondContact O-CE2 3.41Å; Y197-Y199 PolarHBondContact O-N 2.82Å; Y197-E202 VanDerWaalsContact OH-CA 3.23Å; Y197-E202 WeakPolarHBondContact OH-CA 3.49Å; Y197-E202 WeakPolarHBondContact OH-CB 3.19Å; Y197-A204 HydrophobicContact CD2-CB 4.01Å
198N97.4Very high97Very high3 Ų321.6 Ų21.62%0.01611%0.113CC..EExtended strand (participates in β ladder)trans-8190.2172.8-166.7-23.4000109.8A200 F201 E202 T203 I255 G259 F276N198-A200 VanDerWaalsContact C-N 3.26Å; N198-A200 PolarHBondContact O-N 3.28Å; N198-A200 PolarHBondContact OD1-N 3.44Å; N198-F201 CarbonylContact O-C 3.58Å; N198-F201 PolarHBondContact O-N 3.34Å; N198-F201 PolarHBondContact OD1-N 3.23Å; N198-E202 WeakPolarHBondContact O-CA 3.26Å; N198-E202 PolarHBondContact O-N 2.86Å; N198-T203 WeakPolarHBondContact CA-O 3.08Å; N198-T203 VanDerWaalsContact CB-O 3.23Å; N198-T203 WeakPolarHBondContact CB-O 3.44Å; N198-T203 PolarHBondContact N-O 2.79Å; N198-T203 PolarHBondContact O-N 3.44Å; N198-I255 HydrophobicContact CB-CD1 3.9Å; N198-I255 HydrophobicContact CB-CG2 4.3Å; N198-G259 PolarHBondContact ND2-O 3.01Å; N198-G259 WeakPolarHBondContact OD1-CA 3.44Å; N198-F276 HydrophobicContact CB-CE2 4.23Å; N198-F276 WeakPolarHBondContact ND2-CD2 3.44Å; N198-F276 VanDerWaalsContact ND2-CE2 3.27Å; N198-F276 WeakPolarHBondContact ND2-CE2 3.49Å
199Y94.7Very high97Very high44 Ų4425.2 Ų25.217%0.17313%0.13CC..THydrogen-bonded Turntrans-58.9-33.4-178.4-61.5-85.9000113.6Y109 H150 Y197 F201Y109-Y199 AromaticContact CD2-CD1 3.88Å; Y109-Y199 HydrophobicContact CD2-CD1 3.88Å; Y109-Y199 AromaticContact CD2-CD2 3.45Å; Y109-Y199 HydrophobicContact CD2-CD2 3.45Å; Y109-Y199 VanDerWaalsContact CD2-CD2 3.45Å; Y109-Y199 HydrophobicContact CD2-CE1 4.12Å; Y109-Y199 AromaticContact CD2-CE2 3.7Å; Y109-Y199 HydrophobicContact CD2-CE2 3.7Å; Y109-Y199 AromaticContact CD2-CG 3.55Å; Y109-Y199 HydrophobicContact CD2-CG 3.55Å; Y109-Y199 AromaticContact CE2-CD2 3.96Å; Y109-Y199 HydrophobicContact CE2-CD2 3.96Å; Y109-Y199 HydrophobicContact CE2-CG 4Å; Y109-Y199 AromaticContact CG-CD1 3.82Å; Y109-Y199 HydrophobicContact CG-CD1 3.82Å; Y109-Y199 HydrophobicContact CG-CD2 4.22Å; Y109-Y199 AromaticContact CG-CE1 3.96Å; Y109-Y199 HydrophobicContact CG-CE1 3.96Å; Y109-Y199 HydrophobicContact CG-CE2 4.33Å; Y109-Y199 AromaticContact CG-CG 3.97Å; Y109-Y199 HydrophobicContact CG-CG 3.97Å; H150-Y199 VanDerWaalsContact O-CE1 3.27Å; H150-Y199 WeakPolarHBondContact O-CE1 3.34Å; Y197-Y199 AromaticContact CD1-CD1 3.43Å; Y197-Y199 HydrophobicContact CD1-CD1 3.43Å; Y197-Y199 VanDerWaalsContact CD1-CD1 3.43Å; Y197-Y199 HydrophobicContact CD1-CD2 4.23Å; Y197-Y199 AromaticContact CD1-CE1 3.45Å; Y197-Y199 HydrophobicContact CD1-CE1 3.45Å; Y197-Y199 VanDerWaalsContact CD1-CE1 3.45Å; Y197-Y199 HydrophobicContact CD1-CE2 4.27Å; Y197-Y199 AromaticContact CD1-CG 3.83Å; Y197-Y199 HydrophobicContact CD1-CG 3.83Å; Y197-Y199 AromaticContact CD1-CZ 3.9Å; Y197-Y199 AromaticContact CE1-CD1 3.72Å; Y197-Y199 HydrophobicContact CE1-CD1 3.72Å; Y197-Y199 HydrophobicContact CE1-CE1 4.03Å; Y197-Y199 HydrophobicContact CE1-CG 4.28Å; Y197-Y199 HydrophobicContact CG-CE1 4.5Å; Y197-Y199 WeakPolarHBondContact O-CD2 3.49Å; Y197-Y199 VanDerWaalsContact O-CE2 3.26Å; Y197-Y199 WeakPolarHBondContact O-CE2 3.41Å; Y197-Y199 PolarHBondContact O-N 2.82Å; Y199-F201 VanDerWaalsContact C-N 3.32Å; Y199-F201 PolarHBondContact O-N 2.94Å
200A94.6Very high97Very high39 Ų3924.9 Ų24.932%0.32212%0.123SC..THydrogen-bonded Turntrans-67.3-34.1-179.100000112.7N198N198-A200 VanDerWaalsContact C-N 3.26Å; N198-A200 PolarHBondContact O-N 3.28Å; N198-A200 PolarHBondContact OD1-N 3.44Å
201F96.2Very high97Very high42 Ų4219.4 Ų19.418%0.18410%0.1CC..THydrogen-bonded Turntrans-112.16.5-178.4-65.1-74.1000113.6N198 Y199 T203 R228 G259 K260 F276N198-F201 CarbonylContact O-C 3.58Å; N198-F201 PolarHBondContact O-N 3.34Å; N198-F201 PolarHBondContact OD1-N 3.23Å; Y199-F201 VanDerWaalsContact C-N 3.32Å; Y199-F201 PolarHBondContact O-N 2.94Å; F201-T203 VanDerWaalsContact C-N 3.25Å; F201-T203 PolarHBondContact O-N 3.29Å; F201-T203 PolarHBondContact O-OG1 2.75Å; F201-R228 HydrophobicContact CD1-CG 4.26Å; F201-G259 WeakPolarHBondContact CD2-O 3.34Å; F201-G259 WeakPolarHBondContact CE2-O 3.4Å; F201-K260 HydrophobicContact CE2-CG 4.29Å; F201-K260 HydrophobicContact CZ-CG 4.44Å; F201-F276 HydrophobicContact CB-CE1 3.61Å; F201-F276 HydrophobicContact CB-CZ 3.87Å; F201-F276 HydrophobicContact CD1-CE1 4.33Å; F201-F276 AromaticContact CD2-CD1 3.78Å; F201-F276 HydrophobicContact CD2-CD1 3.78Å; F201-F276 AromaticContact CD2-CE1 3.74Å; F201-F276 HydrophobicContact CD2-CE1 3.74Å; F201-F276 HydrophobicContact CE2-CD1 4.17Å; F201-F276 HydrophobicContact CG-CD1 4.12Å; F201-F276 AromaticContact CG-CE1 3.63Å; F201-F276 HydrophobicContact CG-CE1 3.63Å; F201-F276 HydrophobicContact CG-CZ 4.35Å
202E96Very high97.1Very high17 Ų1719.6 Ų19.68%0.07910%0.101CC..THydrogen-bonded Turntrans51.641.6179.1-52.1-170.1131.800113.5N151 Y197 N198 K220 H221N151-E202 WeakPolarHBondContact ND2-CG 3.42Å; N151-E202 PolarHBondContact ND2-OE1 3.2Å; Y197-E202 VanDerWaalsContact OH-CA 3.23Å; Y197-E202 WeakPolarHBondContact OH-CA 3.49Å; Y197-E202 WeakPolarHBondContact OH-CB 3.19Å; N198-E202 WeakPolarHBondContact O-CA 3.26Å; N198-E202 PolarHBondContact O-N 2.86Å; E202-K220 IonicContact OE1-NZ 3.63Å; E202-K220 PolarHBondContact OE1-NZ 2.81Å; E202-K220 IonicContact OE2-NZ 2.7Å; E202-K220 PolarHBondContact OE2-NZ 2.69Å; E202-H221 IonicContact OE2-CD2 3.75Å; E202-H221 IonicContact OE2-CE1 3.65Å; E202-H221 IonicContact OE2-NE2 2.67Å; E202-H221 PolarHBondContact OE2-NE2 2.99Å
203T97.5Very high97.1Very high0 Ų019.6 Ų19.60%010%0.101CC..EExtended strand (participates in β ladder)trans-128.1127.4-171.4-60.90000110.8N198 F201 Y215 W216 P226 F276N198-T203 WeakPolarHBondContact CA-O 3.08Å; N198-T203 VanDerWaalsContact CB-O 3.23Å; N198-T203 WeakPolarHBondContact CB-O 3.44Å; N198-T203 PolarHBondContact N-O 2.79Å; N198-T203 PolarHBondContact O-N 3.44Å; F201-T203 VanDerWaalsContact C-N 3.25Å; F201-T203 PolarHBondContact O-N 3.29Å; F201-T203 PolarHBondContact O-OG1 2.75Å; T203-Y215 HydrophobicContact CG2-CD2 4.15Å; T203-Y215 HydrophobicContact CG2-CG 4.22Å; T203-W216 CarbonylContact C-O 3.51Å; T203-P226 HydrophobicContact CG2-CB 3.98Å; T203-P226 HydrophobicContact CG2-CG 3.67Å; T203-P226 WeakPolarHBondContact OG1-CB 3.44Å; T203-F276 HydrophobicContact CG2-CE2 4.02Å; T203-F276 HydrophobicContact CG2-CZ 3.85Å
204A98Very high97.2Very high0 Ų020 Ų200%010%0.1CC..EExtended strand (participates in β ladder)trans-82.8137.7167.200000110.6I149 E196 Y197 Y215 W216I149-A204 HydrophobicContact CG2-CB 4.12Å; E196-A204 WeakPolarHBondContact O-CA 3.31Å; Y197-A204 HydrophobicContact CD2-CB 4.01Å; A204-Y215 WeakPolarHBondContact O-CA 3.03Å; A204-W216 HydrophobicContact CB-CD2 3.64Å; A204-W216 HydrophobicContact CB-CE3 3.88Å; A204-W216 HydrophobicContact CB-CG 4.31Å; A204-W216 HydrophobicContact CB-CH2 3.68Å; A204-W216 HydrophobicContact CB-CZ2 3.44Å; A204-W216 VanDerWaalsContact CB-CZ2 3.44Å; A204-W216 HydrophobicContact CB-CZ3 3.9Å; A204-W216 PolarHBondContact N-O 2.93Å; A204-W216 PolarHBondContact O-N 3.2Å
205I98.4Very high97.1Very high0 Ų019.4 Ų19.40%010%0.097CC..EExtended strand (participates in β ladder)trans-111.5126.6169.9-55.2176.2000106.4I195 E196 I213 E214 Y215 L253 I255 F262 F276I195-I205 CarbonylContact C-O 3.38Å; I195-I205 WeakPolarHBondContact CA-O 3.49Å; E196-I205 PolarHBondContact N-O 2.67Å; E196-I205 PolarHBondContact O-N 3.18Å; I205-I213 HydrophobicContact CG2-CG2 3.66Å; I205-E214 WeakPolarHBondContact CA-O 3.34Å; I205-Y215 HydrophobicContact CB-CD1 4.46Å; I205-Y215 HydrophobicContact CB-CE1 4.44Å; I205-Y215 HydrophobicContact CD1-CE1 3.92Å; I205-Y215 HydrophobicContact CG1-CD1 3.93Å; I205-Y215 HydrophobicContact CG1-CE1 3.74Å; I205-Y215 HydrophobicContact CG2-CD1 4.22Å; I205-Y215 HydrophobicContact CG2-CE1 4.03Å; I205-L253 HydrophobicContact CB-CD2 3.95Å; I205-L253 HydrophobicContact CG2-CD1 4.48Å; I205-L253 HydrophobicContact CG2-CD2 3.78Å; I205-I255 HydrophobicContact CD1-CD1 4Å; I205-I255 HydrophobicContact CD1-CG1 4.39Å; I205-I255 HydrophobicContact CG1-CD1 4.48Å; I205-F262 HydrophobicContact CD1-CB 4.36Å; I205-F262 HydrophobicContact CD1-CD1 3.78Å; I205-F262 HydrophobicContact CD1-CD2 4.41Å; I205-F262 HydrophobicContact CD1-CE1 4.14Å; I205-F262 HydrophobicContact CD1-CG 3.92Å; I205-F276 HydrophobicContact CD1-CD2 3.95Å; I205-F276 HydrophobicContact CD1-CE2 4.01Å; I205-F276 HydrophobicContact CG1-CE2 4.31Å
206S98.4Very high97.1Very high0 Ų019.4 Ų19.40%010%0.097CC..EExtended strand (participates in β ladder)trans-124.6145.217752.70000110.7H188 L194 I213 E214 W216H188-S206 PolarHBondContact CE1-O 3.25Å; H188-S206 PolarHBondContact NE2-OG 2.84Å; L194-S206 CarbonylContact O-C 3.57Å; L194-S206 VanDerWaalsContact O-CA 3.26Å; L194-S206 WeakPolarHBondContact O-CA 3.41Å; S206-I213 WeakPolarHBondContact O-CA 3.26Å; S206-E214 PolarHBondContact N-O 3.18Å; S206-E214 PolarHBondContact O-N 3.41Å; S206-W216 PolarHBondContact OG-NE1 3.38Å
207I98.5Very high97Very high0 Ų017.7 Ų17.70%09%0.089CC..EExtended strand (participates in β ladder)trans-133.5132.4-179.5-39.8-178.2000109.8C193 L194 M212 I213 L243 P250 L253 V264C193-I207 PolarHBondContact N-O 3.49Å; L194-I207 HydrophobicContact CB-CB 4.27Å; L194-I207 HydrophobicContact CB-CG1 4.46Å; L194-I207 HydrophobicContact CD1-CD1 4.32Å; L194-I207 PolarHBondContact N-O 3.46Å; L194-I207 VanDerWaalsContact N-O 3.09Å; L194-I207 PolarHBondContact O-N 3.1Å; I207-M212 VanDerWaalsContact CA-O 3.28Å; I207-M212 WeakPolarHBondContact CA-O 3.37Å; I207-I213 HydrophobicContact CD1-CD1 4.3Å; I207-I213 HydrophobicContact CD1-CG1 4.04Å; I207-I213 HydrophobicContact CG1-CG1 4.01Å; I207-I213 HydrophobicContact CG1-CG2 4.34Å; I207-I213 HydrophobicContact CG2-CG1 3.98Å; I207-L243 HydrophobicContact CG2-CD1 4.14Å; I207-P250 HydrophobicContact CB-CG 4.26Å; I207-P250 HydrophobicContact CG2-CB 4.25Å; I207-P250 HydrophobicContact CG2-CG 3.64Å; I207-L253 HydrophobicContact CD1-CB 4.34Å; I207-L253 HydrophobicContact CD1-CD1 4.29Å; I207-L253 HydrophobicContact CD1-CD2 4.15Å; I207-L253 HydrophobicContact CG1-CD2 4.27Å; I207-V264 HydrophobicContact CD1-CG1 4.23Å; I207-V264 HydrophobicContact CD1-CG2 3.7Å
208D97.5Very high96.8Very high0 Ų017.4 Ų17.40%09%0.089CC..EExtended strand (participates in β ladder)trans-87.7171.2174.4779.8000114.2H188 P189 K190 E191 C193 I210 G211 M212H188-D208 HydrophobicContact CB-CB 4.03Å; H188-D208 IonicContact ND1-OD2 3.82Å; P189-D208 WeakPolarHBondContact CD-OD2 3.17Å; P189-D208 VanDerWaalsContact CG-OD2 3.22Å; P189-D208 WeakPolarHBondContact CG-OD2 3.39Å; K190-D208 HydrophobicContact CB-CB 4.29Å; K190-D208 PolarHBondContact N-OD2 2.83Å; E191-D208 CarbonylContact O-C 3.6Å; E191-D208 VanDerWaalsContact O-CA 3.27Å; E191-D208 WeakPolarHBondContact O-CA 3.35Å; E191-D208 WeakPolarHBondContact O-CB 3.32Å; C193-D208 VanDerWaalsContact SG-C 3.6Å; D208-I210 PolarHBondContact O-N 2.59Å; D208-I210 VanDerWaalsContact O-N 3.14Å; D208-I210 WeakPolarHBondContact OD1-CG1 3.41Å; D208-I210 PolarHBondContact OD1-N 2.55Å; D208-I210 WeakPolarHBondContact OD2-CG1 3.29Å; D208-G211 PolarHBondContact O-N 3.29Å; D208-G211 PolarHBondContact OD1-N 3.46Å; D208-M212 PolarHBondContact N-O 2.96Å; D208-M212 WeakPolarHBondContact OD1-CB 3.43Å; D208-M212 PolarHBondContact OD1-N 3.04Å; D208-M212 WeakPolarHBondContact OD2-CB 3.27Å
209Q95.8Very high96.6Very high83 Ų8319.4 Ų19.439%0.38810%0.102SC..THydrogen-bonded Turntrans-61-19.3-179.1-75.1178-400114.3E191 C193E191-Q209 HydrophobicContact CB-CG 4.26Å; E191-Q209 WeakPolarHBondContact O-CG 3.46Å; E191-Q209 PolarHBondContact O-N 3.13Å; E191-Q209 PolarHBondContact OE1-NE2 3.12Å; E191-Q209 PolarHBondContact OE2-NE2 2.79Å; E191-Q209 VanDerWaalsContact OE2-NE2 3.15Å; C193-Q209 HydrophobicContact CB-CG 4.06Å
210I95.7Very high96.4Very high72 Ų7223.1 Ų23.137%0.36912%0.119SC..THydrogen-bonded Turntrans-95.5-4.6175.763.4166.7000112.6P189 K190 D208 V244P189-I210 HydrophobicContact CG-CD1 3.75Å; P189-I210 HydrophobicContact CG-CG1 4.45Å; K190-I210 HydrophobicContact CB-CG1 4.35Å; K190-I210 HydrophobicContact CB-CG2 4.35Å; K190-I210 HydrophobicContact CG-CD1 4.25Å; K190-I210 HydrophobicContact CG-CG1 4.25Å; K190-I210 HydrophobicContact CG-CG2 3.82Å; D208-I210 PolarHBondContact O-N 2.59Å; D208-I210 VanDerWaalsContact O-N 3.14Å; D208-I210 WeakPolarHBondContact OD1-CG1 3.41Å; D208-I210 PolarHBondContact OD1-N 2.55Å; D208-I210 WeakPolarHBondContact OD2-CG1 3.29Å; I210-V244 VanDerWaalsContact O-CA 3.31Å; I210-V244 WeakPolarHBondContact O-CA 3.2Å; I210-V244 WeakPolarHBondContact O-CG2 3.37Å
211G96.9Very high96.3Very high0 Ų025 Ų250%012%0.12CC..  trans96.316.7176.200000114.8D208 I213 L243D208-G211 PolarHBondContact O-N 3.29Å; D208-G211 PolarHBondContact OD1-N 3.46Å; G211-I213 PolarHBondContact O-N 3.06Å; G211-L243 WeakPolarHBondContact O-CB 3.18Å
212M97.4Very high96.2Very high21 Ų2126 Ų2610%0.10314%0.136CC..  trans-76.3121.4176.5-169.256.7178.700110.5H188 P189 I207 D208 K235 Y241 V244H188-M212 PolarHBondContact CE1-O 3.1Å; H188-M212 VanDerWaalsContact CE1-O 3.29Å; H188-M212 PolarHBondContact ND1-O 3.22Å; P189-M212 HydrophobicContact CG-CB 4.48Å; I207-M212 VanDerWaalsContact CA-O 3.28Å; I207-M212 WeakPolarHBondContact CA-O 3.37Å; D208-M212 PolarHBondContact N-O 2.96Å; D208-M212 WeakPolarHBondContact OD1-CB 3.43Å; D208-M212 PolarHBondContact OD1-N 3.04Å; D208-M212 WeakPolarHBondContact OD2-CB 3.27Å; M212-K235 HydrophobicContact CE-CD 3.8Å; M212-Y241 HydrophobicContact CE-CD1 4.18Å; M212-Y241 HydrophobicContact CE-CE1 3.29Å; M212-Y241 WeakPolarHBondContact CE-OH 3.43Å; M212-Y241 HydrophobicContact SD-CD1 3.7Å; M212-Y241 HydrophobicContact SD-CE1 3.39Å; M212-Y241 WeakPolarHBondContact SD-CE1 3.12Å; M212-V244 HydrophobicContact CB-CG2 4.37Å
213I98.1Very high96.2Very high0 Ų027 Ų270%014%0.14CC..EExtended strand (participates in β ladder)trans-99.2128.7-179.1-52177.3000110.2I205 S206 I207 G211 Y215 K235 L240 L243 F262 Y274I205-I213 HydrophobicContact CG2-CG2 3.66Å; S206-I213 WeakPolarHBondContact O-CA 3.26Å; I207-I213 HydrophobicContact CD1-CD1 4.3Å; I207-I213 HydrophobicContact CD1-CG1 4.04Å; I207-I213 HydrophobicContact CG1-CG1 4.01Å; I207-I213 HydrophobicContact CG1-CG2 4.34Å; I207-I213 HydrophobicContact CG2-CG1 3.98Å; G211-I213 PolarHBondContact O-N 3.06Å; I213-Y215 HydrophobicContact CG2-CD1 4.49Å; I213-Y215 HydrophobicContact CG2-CE1 4.3Å; I213-K235 PolarHBondContact O-NZ 3.48Å; I213-L240 HydrophobicContact CB-CB 4.27Å; I213-L240 HydrophobicContact CB-CD2 4.1Å; I213-L240 HydrophobicContact CD1-CD2 4.01Å; I213-L240 HydrophobicContact CG2-CD2 3.99Å; I213-L243 HydrophobicContact CD1-CD1 3.93Å; I213-L243 HydrophobicContact CG1-CD1 4.12Å; I213-F262 HydrophobicContact CD1-CE2 4.36Å; I213-Y274 HydrophobicContact CD1-CE1 4.32Å; I213-Y274 HydrophobicContact CD1-CE2 4.5Å
214E97.2Very high96Very high33 Ų3333.4 Ų33.415%0.15417%0.17CC..EExtended strand (participates in β ladder)trans-123.3142.7177.3-68.3-65.2156.800111.9M187 H188 I205 S206 K235M187-E214 HydrophobicContact CE-CB 4.25Å; H188-E214 WeakPolarHBondContact CE1-CG 3.36Å; H188-E214 WeakPolarHBondContact NE2-CG 3.47Å; I205-E214 WeakPolarHBondContact CA-O 3.34Å; S206-E214 PolarHBondContact N-O 3.18Å; S206-E214 PolarHBondContact O-N 3.41Å; E214-K235 IonicContact OE1-NZ 3.07Å; E214-K235 PolarHBondContact OE1-NZ 2.87Å; E214-K235 WeakPolarHBondContact OE2-CE 3.32Å; E214-K235 IonicContact OE2-NZ 3.57Å; E214-K235 PolarHBondContact OE2-NZ 2.82Å
215Y97.6Very high95.9Very high3 Ų337.8 Ų37.81%0.01219%0.189CC..EExtended strand (participates in β ladder)trans-111.1134.4173.6-79.523.3000109.7T203 A204 I205 I213 P226 V230 W232 F262 F276T203-Y215 HydrophobicContact CG2-CD2 4.15Å; T203-Y215 HydrophobicContact CG2-CG 4.22Å; A204-Y215 WeakPolarHBondContact O-CA 3.03Å; I205-Y215 HydrophobicContact CB-CD1 4.46Å; I205-Y215 HydrophobicContact CB-CE1 4.44Å; I205-Y215 HydrophobicContact CD1-CE1 3.92Å; I205-Y215 HydrophobicContact CG1-CD1 3.93Å; I205-Y215 HydrophobicContact CG1-CE1 3.74Å; I205-Y215 HydrophobicContact CG2-CD1 4.22Å; I205-Y215 HydrophobicContact CG2-CE1 4.03Å; I213-Y215 HydrophobicContact CG2-CD1 4.49Å; I213-Y215 HydrophobicContact CG2-CE1 4.3Å; Y215-P226 HydrophobicContact CD2-CG 4.1Å; Y215-V230 HydrophobicContact CD2-CG2 3.98Å; Y215-V230 HydrophobicContact CE2-CG2 4.07Å; Y215-W232 AromaticContact CD2-CZ2 3.89Å; Y215-W232 HydrophobicContact CD2-CZ2 3.89Å; Y215-W232 HydrophobicContact CE2-CZ2 4.1Å; Y215-W232 HydrophobicContact CG-CZ2 4.18Å; Y215-F262 HydrophobicContact CE1-CE1 4.34Å; Y215-F262 HydrophobicContact CE1-CZ 4.43Å; Y215-F262 WeakPolarHBondContact OH-CE1 3.33Å; Y215-F276 HydrophobicContact CD2-CE2 4.09Å; Y215-F276 HydrophobicContact CD2-CZ 4.3Å; Y215-F276 AromaticContact CE2-CD2 3.78Å; Y215-F276 HydrophobicContact CE2-CD2 3.78Å; Y215-F276 AromaticContact CE2-CE2 3.45Å; Y215-F276 HydrophobicContact CE2-CE2 3.45Å; Y215-F276 VanDerWaalsContact CE2-CE2 3.45Å; Y215-F276 HydrophobicContact CE2-CG 4.47Å; Y215-F276 AromaticContact CE2-CZ 3.88Å; Y215-F276 HydrophobicContact CE2-CZ 3.88Å; Y215-F276 AromaticContact CZ-CD2 3.74Å; Y215-F276 AromaticContact CZ-CE2 3.74Å; Y215-F276 WeakPolarHBondContact OH-CD2 3.5Å; Y215-F276 PolarHBondContact OH-O 2.97Å
216W97.4Very high95.7Very high2 Ų238 Ų381%0.00819%0.19CC..EExtended strand (participates in β ladder)trans-157.4166.7178.953.3-84.2000110.1I149 A160 I171 F184 M187 I195 T203 A204 S206I149-W216 HydrophobicContact CD1-CH2 3.98Å; I149-W216 HydrophobicContact CD1-CZ3 3.78Å; I149-W216 HydrophobicContact CG2-CH2 4.04Å; A160-W216 HydrophobicContact CB-CH2 3.75Å; A160-W216 HydrophobicContact CB-CZ2 4.28Å; I171-W216 HydrophobicContact CD1-CH2 3.79Å; I171-W216 HydrophobicContact CD1-CZ3 3.97Å; F184-W216 HydrophobicContact CE2-CD2 4.07Å; F184-W216 AromaticContact CE2-CE3 3.56Å; F184-W216 HydrophobicContact CE2-CE3 3.56Å; F184-W216 HydrophobicContact CE2-CH2 4.2Å; F184-W216 AromaticContact CE2-CZ3 3.65Å; F184-W216 HydrophobicContact CE2-CZ3 3.65Å; F184-W216 HydrophobicContact CZ-CB 4.46Å; F184-W216 AromaticContact CZ-CD2 3.95Å; F184-W216 HydrophobicContact CZ-CD2 3.95Å; F184-W216 AromaticContact CZ-CE3 3.49Å; F184-W216 HydrophobicContact CZ-CE3 3.49Å; F184-W216 VanDerWaalsContact CZ-CE3 3.49Å; F184-W216 HydrophobicContact CZ-CG 4.38Å; F184-W216 HydrophobicContact CZ-CZ3 4.04Å; M187-W216 HydrophobicContact CE-CB 3.97Å; M187-W216 HydrophobicContact CE-CG 4.14Å; I195-W216 HydrophobicContact CG2-CZ2 4.02Å; T203-W216 CarbonylContact C-O 3.51Å; A204-W216 HydrophobicContact CB-CD2 3.64Å; A204-W216 HydrophobicContact CB-CE3 3.88Å; A204-W216 HydrophobicContact CB-CG 4.31Å; A204-W216 HydrophobicContact CB-CH2 3.68Å; A204-W216 HydrophobicContact CB-CZ2 3.44Å; A204-W216 VanDerWaalsContact CB-CZ2 3.44Å; A204-W216 HydrophobicContact CB-CZ3 3.9Å; A204-W216 PolarHBondContact N-O 2.93Å; A204-W216 PolarHBondContact O-N 3.2Å; S206-W216 PolarHBondContact OG-NE1 3.38Å
217T96.4Very high95.1Very high5 Ų544.5 Ų44.53%0.03123%0.23CC..EExtended strand (participates in β ladder)trans-112.2164.7-173.958.10000113.3H221 Y223 E224 P226T217-H221 HydrophobicContact CG2-CB 4.11Å; T217-H221 WeakPolarHBondContact OG1-CB 3.49Å; T217-H221 PolarHBondContact OG1-O 3.3Å; T217-Y223 WeakPolarHBondContact O-CA 3.15Å; T217-E224 WeakPolarHBondContact CB-O 2.67Å; T217-E224 WeakPolarHBondContact CG2-O 3.47Å; T217-E224 PolarHBondContact N-O 2.8Å; T217-E224 PolarHBondContact OG1-N 2.86Å; T217-E224 PolarHBondContact OG1-O 3Å; T217-P226 HydrophobicContact CG2-CB 3.79Å
218G93.3Very high94.8Very high2 Ų251.2 Ų51.22%0.02126%0.256CS..  trans-79-173.2177.400000114.2K220 H221 A222 Y223G218-K220 PolarHBondContact O-N 3.46Å; G218-K220 VanDerWaalsContact O-N 3.11Å; G218-H221 PolarHBondContact O-N 3.38Å; G218-H221 VanDerWaalsContact O-N 3.08Å; G218-A222 PolarHBondContact O-N 3.21Å; G218-Y223 PolarHBondContact O-N 3.31Å
219P92.4Very high94.5Very high45 Ų4552.4 Ų52.429%0.29227%0.268SS..G310 helixtrans-54.8-33.7-177.8-2329.6000114.4A158 H221 A222 Y223A158-P219 HydrophobicContact CB-CG 3.69Å; P219-H221 PolarHBondContact O-N 3.05Å; P219-A222 PolarHBondContact O-N 3.01Å; P219-Y223 HydrophobicContact CB-CE1 4.22Å; P219-Y223 HydrophobicContact CG-CE1 3.86Å; P219-Y223 WeakPolarHBondContact CG-OH 3.25Å
220K91Very high94.5Very high121 Ų12149.3 Ų49.353%0.52626%0.255SS..G310 helixtrans-59.3-30.7180-177.4178.5175.5-176.60113.5E202 G218E202-K220 IonicContact OE1-NZ 3.63Å; E202-K220 PolarHBondContact OE1-NZ 2.81Å; E202-K220 IonicContact OE2-NZ 2.7Å; E202-K220 PolarHBondContact OE2-NZ 2.69Å; G218-K220 PolarHBondContact O-N 3.46Å; G218-K220 VanDerWaalsContact O-N 3.11Å
221H93.1Very high94.4Very high78 Ų7851.7 Ų51.736%0.36127%0.268SS..G310 helixtrans-115.826.5-178.8-58-64.4000111.3E202 T217 G218 P219 Y223 E224E202-H221 IonicContact OE2-CD2 3.75Å; E202-H221 IonicContact OE2-CE1 3.65Å; E202-H221 IonicContact OE2-NE2 2.67Å; E202-H221 PolarHBondContact OE2-NE2 2.99Å; T217-H221 HydrophobicContact CG2-CB 4.11Å; T217-H221 WeakPolarHBondContact OG1-CB 3.49Å; T217-H221 PolarHBondContact OG1-O 3.3Å; G218-H221 PolarHBondContact O-N 3.38Å; G218-H221 VanDerWaalsContact O-N 3.08Å; P219-H221 PolarHBondContact O-N 3.05Å; H221-Y223 PolarHBondContact O-N 3.05Å; H221-Y223 VanDerWaalsContact O-N 3.07Å; H221-E224 PolarHBondContact O-N 2.81Å
222A94Very high94.3Very high63 Ų6352.3 Ų52.352%0.52127%0.27SS..THydrogen-bonded Turntrans53.731.3173.400000115.2G218 P219 E224G218-A222 PolarHBondContact O-N 3.21Å; P219-A222 PolarHBondContact O-N 3.01Å; A222-E224 HydrophobicContact CB-CG 4.5Å; A222-E224 PolarHBondContact O-N 3.37Å
223Y95.2Very high93.9Very high40 Ų4058.6 Ų58.616%0.15730%0.3CS..THydrogen-bonded Turntrans65.219.8174.4-47.4-70000115.1I171 H182 F184 T217 G218 P219 H221I171-Y223 HydrophobicContact CB-CE1 4.38Å; I171-Y223 HydrophobicContact CG1-CD1 4.44Å; I171-Y223 HydrophobicContact CG1-CE1 3.97Å; I171-Y223 HydrophobicContact CG2-CE1 4.19Å; H182-Y223 HydrophobicContact CB-CD1 4.41Å; H182-Y223 HydrophobicContact CB-CD2 3.93Å; H182-Y223 HydrophobicContact CB-CE1 3.99Å; H182-Y223 HydrophobicContact CB-CE2 3.46Å; H182-Y223 VanDerWaalsContact CB-CE2 3.46Å; H182-Y223 HydrophobicContact CB-CG 4.37Å; H182-Y223 VanDerWaalsContact CB-CZ 3.47Å; H182-Y223 AromaticContact CD2-CD2 3.73Å; H182-Y223 AromaticContact CD2-CG 3.65Å; H182-Y223 AromaticContact CG-CD2 3.52Å; H182-Y223 AromaticContact CG-CE2 3.59Å; H182-Y223 AromaticContact CG-CG 3.9Å; H182-Y223 AromaticContact ND1-CD2 3.73Å; H182-Y223 AromaticContact ND1-CE2 3.93Å; F184-Y223 HydrophobicContact CE2-CD1 4.32Å; F184-Y223 HydrophobicContact CZ-CD1 4.12Å; F184-Y223 HydrophobicContact CZ-CG 4.19Å; T217-Y223 WeakPolarHBondContact O-CA 3.15Å; G218-Y223 PolarHBondContact O-N 3.31Å; P219-Y223 HydrophobicContact CB-CE1 4.22Å; P219-Y223 HydrophobicContact CG-CE1 3.86Å; P219-Y223 WeakPolarHBondContact CG-OH 3.25Å; H221-Y223 PolarHBondContact O-N 3.05Å; H221-Y223 VanDerWaalsContact O-N 3.07Å
224E94.8Very high93.6Very high134 Ų13465.6 Ų65.663%0.62633%0.327SS*.PPolyproline II helixtrans-83.7173.3-178.6-61.9-173172.100112.5T217 H221 A222T217-E224 WeakPolarHBondContact CB-O 2.67Å; T217-E224 WeakPolarHBondContact CG2-O 3.47Å; T217-E224 PolarHBondContact N-O 2.8Å; T217-E224 PolarHBondContact OG1-N 2.86Å; T217-E224 PolarHBondContact OG1-O 3Å; H221-E224 PolarHBondContact O-N 2.81Å; A222-E224 HydrophobicContact CB-CG 4.5Å; A222-E224 PolarHBondContact O-N 3.37Å
225F94.4Very high93.3Very high91 Ų9165.5 Ų65.540%0.39933%0.326SS..PPolyproline II helixtrans-64.1135.3170.2-175.6-95.9000110.5T227 V230 W232F225-T227 PolarHBondContact O-N 2.98Å; F225-V230 HydrophobicContact CE1-CG1 3.92Å; F225-V230 HydrophobicContact CZ-CG1 3.78Å; F225-W232 AromaticContact CE2-CH2 3.47Å; F225-W232 HydrophobicContact CE2-CH2 3.47Å; F225-W232 VanDerWaalsContact CE2-CH2 3.47Å; F225-W232 HydrophobicContact CE2-CZ2 4.07Å; F225-W232 AromaticContact CE2-CZ3 3.81Å; F225-W232 HydrophobicContact CE2-CZ3 3.81Å; F225-W232 HydrophobicContact CZ-CD2 4.44Å; F225-W232 HydrophobicContact CZ-CE3 4.11Å; F225-W232 AromaticContact CZ-CH2 3.57Å; F225-W232 HydrophobicContact CZ-CH2 3.57Å; F225-W232 AromaticContact CZ-CZ2 3.91Å; F225-W232 HydrophobicContact CZ-CZ2 3.91Å; F225-W232 AromaticContact CZ-CZ3 3.66Å; F225-W232 HydrophobicContact CZ-CZ3 3.66Å
226P94.1Very high93.1Very high4 Ų471.4 Ų71.43%0.02636%0.362CS..PPolyproline II helixtrans-66.8133.2-177.329.5-39.7000112.8T203 Y215 T217 V230T203-P226 HydrophobicContact CG2-CB 3.98Å; T203-P226 HydrophobicContact CG2-CG 3.67Å; T203-P226 WeakPolarHBondContact OG1-CB 3.44Å; Y215-P226 HydrophobicContact CD2-CG 4.1Å; T217-P226 HydrophobicContact CG2-CB 3.79Å; P226-V230 HydrophobicContact CB-CG2 4.24Å; P226-V230 HydrophobicContact CG-CG2 3.87Å
227T87.3Confident93Very high137 Ų13775.6 Ų75.684%0.8438%0.382SS*.  trans-95.9-16.8171.7540000112.8F225F225-T227 PolarHBondContact O-N 2.98Å
228R90.3Very high93Very high141 Ų14176 Ų7653%0.53238%0.384SS..SBendtrans-92.6117.3-173.9-168.4-176.6177-171.8-4.2111.3F201 V230F201-R228 HydrophobicContact CD1-CG 4.26Å; R228-V230 VanDerWaalsContact C-N 3.25Å; R228-V230 PolarHBondContact O-N 2.65Å
229G91.7Very high93.2Very high25 Ų2578.9 Ų78.926%0.25840%0.399SS..SBendtrans74.414.3173.900000114.6S277G229-S277 WeakPolarHBondContact O-CA 3.26Å; G229-S277 WeakPolarHBondContact O-CB 3.22Å
230V95.2Very high93.4Very high19 Ų1976.8 Ų76.812%0.11539%0.386CS..  trans-114.4117.9175.4178.90000108.5Y215 F225 P226 R228 W232 F276Y215-V230 HydrophobicContact CD2-CG2 3.98Å; Y215-V230 HydrophobicContact CE2-CG2 4.07Å; F225-V230 HydrophobicContact CE1-CG1 3.92Å; F225-V230 HydrophobicContact CZ-CG1 3.78Å; P226-V230 HydrophobicContact CB-CG2 4.24Å; P226-V230 HydrophobicContact CG-CG2 3.87Å; R228-V230 VanDerWaalsContact C-N 3.25Å; R228-V230 PolarHBondContact O-N 2.65Å; V230-W232 HydrophobicContact CG1-CD2 4.09Å; V230-W232 HydrophobicContact CG1-CG 4.07Å; V230-W232 HydrophobicContact CG1-CZ2 4.31Å; V230-F276 HydrophobicContact CG2-CE1 3.9Å; V230-F276 HydrophobicContact CG2-CZ 4.07Å
231D94.5Very high93.7Very high122 Ų12276 Ų7665%0.65238%0.38SS*.  trans-104.48.5-171.5-51-38.3000112.5S277D231-S277 PolarHBondContact N-O 2.91Å; D231-S277 WeakPolarHBondContact OD2-CB 3.23Å; D231-S277 PolarHBondContact OD2-OG 3.29Å
232W94.1Very high93.9Very high12 Ų1275 Ų755%0.04538%0.376CS..  trans-119.9149.217957.9-85.4000111Y215 F225 V230 K235 T238 L240 S277 N278Y215-W232 AromaticContact CD2-CZ2 3.89Å; Y215-W232 HydrophobicContact CD2-CZ2 3.89Å; Y215-W232 HydrophobicContact CE2-CZ2 4.1Å; Y215-W232 HydrophobicContact CG-CZ2 4.18Å; F225-W232 AromaticContact CE2-CH2 3.47Å; F225-W232 HydrophobicContact CE2-CH2 3.47Å; F225-W232 VanDerWaalsContact CE2-CH2 3.47Å; F225-W232 HydrophobicContact CE2-CZ2 4.07Å; F225-W232 AromaticContact CE2-CZ3 3.81Å; F225-W232 HydrophobicContact CE2-CZ3 3.81Å; F225-W232 HydrophobicContact CZ-CD2 4.44Å; F225-W232 HydrophobicContact CZ-CE3 4.11Å; F225-W232 AromaticContact CZ-CH2 3.57Å; F225-W232 HydrophobicContact CZ-CH2 3.57Å; F225-W232 AromaticContact CZ-CZ2 3.91Å; F225-W232 HydrophobicContact CZ-CZ2 3.91Å; F225-W232 AromaticContact CZ-CZ3 3.66Å; F225-W232 HydrophobicContact CZ-CZ3 3.66Å; V230-W232 HydrophobicContact CG1-CD2 4.09Å; V230-W232 HydrophobicContact CG1-CG 4.07Å; V230-W232 HydrophobicContact CG1-CZ2 4.31Å; W232-K235 HydrophobicContact CH2-CG 4.18Å; W232-K235 HydrophobicContact CZ3-CG 3.78Å; W232-T238 HydrophobicContact CB-CG2 4.03Å; W232-T238 HydrophobicContact CD2-CG2 3.5Å; W232-T238 HydrophobicContact CE3-CG2 3.91Å; W232-T238 HydrophobicContact CG-CG2 3.57Å; W232-L240 HydrophobicContact CH2-CD1 3.83Å; W232-L240 HydrophobicContact CZ2-CD1 3.61Å; W232-S277 VanDerWaalsContact CD1-O 3.22Å; W232-N278 VanDerWaalsContact CD1-C 3.49Å
233Q89.5Confident94.1Very high154 Ų15472 Ų7272%0.7235%0.351SS*.SBendtrans-108.9-34.7178.2-67.3-177.50.600111.7E237Q233-E237 PolarHBondContact N-OE2 2.82Å
234Y92Very high94.2Very high147 Ų14772.5 Ų72.558%0.57636%0.358SS*.SBendtrans-121.1135.6-177.4-57.3-79.3000110.9V236 E237Y234-V236 PolarHBondContact O-N 2.81Å; Y234-V236 VanDerWaalsContact O-N 3.07Å; Y234-E237 VanDerWaalsContact O-CB 3.26Å; Y234-E237 WeakPolarHBondContact O-CB 3.41Å; Y234-E237 WeakPolarHBondContact O-CG 3.26Å; Y234-E237 PolarHBondContact O-N 2.76Å
235K91.9Very high94.2Very high30 Ų3073.8 Ų73.813%0.1336%0.361CS..G310 helixtrans-60-23.9-179.9-65-169.6174.7-160.20114.4M212 I213 E214 W232 E237 T238 Y241M212-K235 HydrophobicContact CE-CD 3.8Å; I213-K235 PolarHBondContact O-NZ 3.48Å; E214-K235 IonicContact OE1-NZ 3.07Å; E214-K235 PolarHBondContact OE1-NZ 2.87Å; E214-K235 WeakPolarHBondContact OE2-CE 3.32Å; E214-K235 IonicContact OE2-NZ 3.57Å; E214-K235 PolarHBondContact OE2-NZ 2.82Å; W232-K235 HydrophobicContact CH2-CG 4.18Å; W232-K235 HydrophobicContact CZ3-CG 3.78Å; K235-E237 PolarHBondContact O-N 3.04Å; K235-T238 WeakPolarHBondContact O-CB 3.17Å; K235-T238 PolarHBondContact O-N 2.84Å; K235-T238 PolarHBondContact O-OG1 2.82Å; K235-Y241 HydrophobicContact CB-CD2 4.4Å; K235-Y241 HydrophobicContact CB-CE2 3.46Å; K235-Y241 VanDerWaalsContact CB-CE2 3.46Å; K235-Y241 HydrophobicContact CD-CE2 4.23Å
236V93.5Very high94.3Very high127 Ų12771.3 Ų71.377%0.7736%0.358SS*.G310 helixtrans-63.9-15.8175.1-61.20000112.9Y234 T238Y234-V236 PolarHBondContact O-N 2.81Å; Y234-V236 VanDerWaalsContact O-N 3.07Å; V236-T238 VanDerWaalsContact C-N 3.29Å
237E94.4Very high94.4Very high91 Ų9180.2 Ų80.243%0.42540%0.396SS..G310 helixtrans-83.8-7174.8-57.4171.4168.800112.7Q233 Y234 K235 K280Q233-E237 PolarHBondContact N-OE2 2.82Å; Y234-E237 VanDerWaalsContact O-CB 3.26Å; Y234-E237 WeakPolarHBondContact O-CB 3.41Å; Y234-E237 WeakPolarHBondContact O-CG 3.26Å; Y234-E237 PolarHBondContact O-N 2.76Å; K235-E237 PolarHBondContact O-N 3.04Å; E237-K280 WeakPolarHBondContact O-CE 3.18Å
238T96.8Very high94.8Very high12 Ų1274.2 Ų74.27%0.07436%0.359CS..SBendtrans-118.4170.3-170.2780000111.5W232 K235 V236 L240 N278W232-T238 HydrophobicContact CB-CG2 4.03Å; W232-T238 HydrophobicContact CD2-CG2 3.5Å; W232-T238 HydrophobicContact CE3-CG2 3.91Å; W232-T238 HydrophobicContact CG-CG2 3.57Å; K235-T238 WeakPolarHBondContact O-CB 3.17Å; K235-T238 PolarHBondContact O-N 2.84Å; K235-T238 PolarHBondContact O-OG1 2.82Å; V236-T238 VanDerWaalsContact C-N 3.29Å; T238-L240 HydrophobicContact CG2-CD1 4.31Å; T238-L240 HydrophobicContact CG2-CG 4.48Å; T238-L240 WeakPolarHBondContact OG1-CB 3.27Å; T238-L240 VanDerWaalsContact OG1-CG 3.24Å; T238-L240 WeakPolarHBondContact OG1-CG 3.47Å; T238-L240 PolarHBondContact OG1-N 2.8Å; T238-N278 WeakPolarHBondContact CG2-O 3.44Å
239D97.7Very high95.1Very high64 Ų6470 Ų7034%0.34235%0.349SS..SBendtrans-99.918.3172.9-60.4-40.9000112Y241 E242 Y274 G279 K280 I281D239-Y241 PolarHBondContact O-N 2.82Å; D239-E242 VanDerWaalsContact O-CB 3.24Å; D239-E242 WeakPolarHBondContact O-CB 3.26Å; D239-E242 PolarHBondContact O-N 2.87Å; D239-Y274 HydrophobicContact CB-CE1 4.42Å; D239-G279 PolarHBondContact N-O 3.33Å; D239-K280 VanDerWaalsContact OD2-CA 3.28Å; D239-K280 WeakPolarHBondContact OD2-CA 3.25Å; D239-K280 WeakPolarHBondContact OD2-CB 3.41Å; D239-I281 HydrophobicContact CB-CB 4.35Å; D239-I281 HydrophobicContact CB-CD1 4.03Å; D239-I281 HydrophobicContact CB-CG1 3.83Å; D239-I281 PolarHBondContact OD2-N 2.9Å
240L97Very high95.3Very high1 Ų169 Ų691%0.00534%0.338CS..THydrogen-bonded Turntrans-64.8-12.8-176.2-64179000113.8I213 W232 T238 F262 Y274I213-L240 HydrophobicContact CB-CB 4.27Å; I213-L240 HydrophobicContact CB-CD2 4.1Å; I213-L240 HydrophobicContact CD1-CD2 4.01Å; I213-L240 HydrophobicContact CG2-CD2 3.99Å; W232-L240 HydrophobicContact CH2-CD1 3.83Å; W232-L240 HydrophobicContact CZ2-CD1 3.61Å; T238-L240 HydrophobicContact CG2-CD1 4.31Å; T238-L240 HydrophobicContact CG2-CG 4.48Å; T238-L240 WeakPolarHBondContact OG1-CB 3.27Å; T238-L240 VanDerWaalsContact OG1-CG 3.24Å; T238-L240 WeakPolarHBondContact OG1-CG 3.47Å; T238-L240 PolarHBondContact OG1-N 2.8Å; L240-F262 HydrophobicContact CD2-CZ 4.12Å; L240-Y274 HydrophobicContact CD2-CD1 4.23Å; L240-Y274 HydrophobicContact CD2-CE1 4.45Å
241Y96.4Very high95.4Very high105 Ų10568.7 Ų68.741%0.41234%0.336SS..THydrogen-bonded Turntrans-90.9-1.7173.6-69-78.6000114.1M212 K235 D239 L243 V244 K245M212-Y241 HydrophobicContact CE-CD1 4.18Å; M212-Y241 HydrophobicContact CE-CE1 3.29Å; M212-Y241 WeakPolarHBondContact CE-OH 3.43Å; M212-Y241 HydrophobicContact SD-CD1 3.7Å; M212-Y241 HydrophobicContact SD-CE1 3.39Å; M212-Y241 WeakPolarHBondContact SD-CE1 3.12Å; K235-Y241 HydrophobicContact CB-CD2 4.4Å; K235-Y241 HydrophobicContact CB-CE2 3.46Å; K235-Y241 VanDerWaalsContact CB-CE2 3.46Å; K235-Y241 HydrophobicContact CD-CE2 4.23Å; D239-Y241 PolarHBondContact O-N 2.82Å; Y241-L243 VanDerWaalsContact C-N 3.3Å; Y241-L243 PolarHBondContact O-N 2.56Å; Y241-V244 PolarHBondContact O-N 3.49Å; Y241-K245 PolarHBondContact O-N 2.85Å
242E97.2Very high95.5Very high56 Ų5662.9 Ų62.926%0.26231%0.305SS..Hα-helixtrans-61.3-37.5-172.9179.858.5-15900112.6D239 K245 A246 I281D239-E242 VanDerWaalsContact O-CB 3.24Å; D239-E242 WeakPolarHBondContact O-CB 3.26Å; D239-E242 PolarHBondContact O-N 2.87Å; E242-K245 PolarHBondContact O-N 2.95Å; E242-K245 IonicContact OE2-NZ 2.82Å; E242-A246 VanDerWaalsContact O-CB 3.29Å; E242-A246 WeakPolarHBondContact O-CB 3.36Å; E242-A246 PolarHBondContact O-N 3.35Å; E242-I281 HydrophobicContact CB-CD1 3.68Å; E242-I281 HydrophobicContact CG-CD1 3.54Å
243L97.7Very high95.7Very high0 Ų062.4 Ų62.40%030%0.303CS..Hα-helixtrans-64.4-42.8178-58.8174.3000111.6I207 G211 I213 Y241 A246 K247 V248 P250 V264I207-L243 HydrophobicContact CG2-CD1 4.14Å; G211-L243 WeakPolarHBondContact O-CB 3.18Å; I213-L243 HydrophobicContact CD1-CD1 3.93Å; I213-L243 HydrophobicContact CG1-CD1 4.12Å; Y241-L243 VanDerWaalsContact C-N 3.3Å; Y241-L243 PolarHBondContact O-N 2.56Å; L243-A246 CarbonylContact O-C 3.59Å; L243-A246 PolarHBondContact O-N 2.91Å; L243-K247 PolarHBondContact O-N 2.81Å; L243-V248 HydrophobicContact CB-CG2 4.09Å; L243-V248 HydrophobicContact CD2-CG2 3.73Å; L243-V248 PolarHBondContact O-N 3.34Å; L243-P250 HydrophobicContact CD1-CB 4.28Å; L243-V264 HydrophobicContact CD1-CG1 3.97Å; L243-V264 HydrophobicContact CD2-CG1 4.33Å
244V97Very high96.2Very high50 Ų5055.9 Ų55.930%0.30327%0.274SS..Hα-helixtrans-61.8-46175.9-1760000110.7I210 M212 Y241 A246 K247I210-V244 VanDerWaalsContact O-CA 3.31Å; I210-V244 WeakPolarHBondContact O-CA 3.2Å; I210-V244 WeakPolarHBondContact O-CG2 3.37Å; M212-V244 HydrophobicContact CB-CG2 4.37Å; Y241-V244 PolarHBondContact O-N 3.49Å; V244-A246 VanDerWaalsContact C-N 3.33Å; V244-A246 PolarHBondContact O-N 2.96Å; V244-K247 PolarHBondContact O-N 3.31Å; V244-K247 VanDerWaalsContact O-N 3.1Å
245K96.3Very high96.5Very high161 Ų16150.2 Ų50.270%0.725%0.253SS*.Hα-helixtrans-61.8-41.6177.9-179.4-174.9169.5-162.10111.8Y241 E242 K247Y241-K245 PolarHBondContact O-N 2.85Å; E242-K245 PolarHBondContact O-N 2.95Å; E242-K245 IonicContact OE2-NZ 2.82Å; K245-K247 PolarHBondContact O-N 2.69Å
246A96.1Very high96.7Very high40 Ų4051.4 Ų51.433%0.33126%0.257SS..Hα-helixtrans-74.5-13.3176.700000113.2E242 L243 V244 V248E242-A246 VanDerWaalsContact O-CB 3.29Å; E242-A246 WeakPolarHBondContact O-CB 3.36Å; E242-A246 PolarHBondContact O-N 3.35Å; L243-A246 CarbonylContact O-C 3.59Å; L243-A246 PolarHBondContact O-N 2.91Å; V244-A246 VanDerWaalsContact C-N 3.33Å; V244-A246 PolarHBondContact O-N 2.96Å; A246-V248 VanDerWaalsContact C-N 3.32Å; A246-V248 HydrophobicContact CB-CG1 3.95Å; A246-V248 HydrophobicContact CB-CG2 4.11Å; A246-V248 PolarHBondContact O-N 3.05Å
247K96.6Very high96.9Very high191 Ų19148.2 Ų48.283%0.8324%0.239SC*.THydrogen-bonded Turntrans56.344.2-176.6-56.4178.7179.9178.90112.4L243 V244 K245L243-K247 PolarHBondContact O-N 2.81Å; V244-K247 PolarHBondContact O-N 3.31Å; V244-K247 VanDerWaalsContact O-N 3.1Å; K245-K247 PolarHBondContact O-N 2.69Å
248V95.9Very high96.9Very high10 Ų1046.6 Ų46.66%0.06123%0.233CC..  trans-108.8147.8-178.3-61.90000110.9L243 A246 D268L243-V248 HydrophobicContact CB-CG2 4.09Å; L243-V248 HydrophobicContact CD2-CG2 3.73Å; L243-V248 PolarHBondContact O-N 3.34Å; A246-V248 VanDerWaalsContact C-N 3.32Å; A246-V248 HydrophobicContact CB-CG1 3.95Å; A246-V248 HydrophobicContact CB-CG2 4.11Å; A246-V248 PolarHBondContact O-N 3.05Å; V248-D268 HydrophobicContact CG1-CB 3.83Å
249V94.9Very high96.9Very high52 Ų5246 Ų4632%0.31523%0.23SC..  trans-92.6123.9176.1-178.70000108.3S266 N267V249-S266 CarbonylContact O-C 3.52Å; V249-S266 VanDerWaalsContact O-CA 3.32Å; V249-S266 WeakPolarHBondContact O-CA 3.46Å; V249-S266 WeakPolarHBondContact O-CB 3.34Å; V249-N267 HydrophobicContact CB-CB 4.39Å; V249-N267 PolarHBondContact N-OD1 3.02Å; V249-N267 PolarHBondContact O-N 3.38Å; V249-N267 PolarHBondContact O-OD1 3.25Å
250P97.3Very high96.9Very high4 Ų448.8 Ų48.83%0.02624%0.239CC..EExtended strand (participates in β ladder)trans-77.5136.3177.534.7-35.8000110.3L194 I207 L243 V264L194-P250 HydrophobicContact CD1-CB 3.69Å; L194-P250 HydrophobicContact CD1-CG 4.17Å; I207-P250 HydrophobicContact CB-CG 4.26Å; I207-P250 HydrophobicContact CG2-CB 4.25Å; I207-P250 HydrophobicContact CG2-CG 3.64Å; L243-P250 HydrophobicContact CD1-CB 4.28Å; P250-V264 HydrophobicContact CB-CG1 3.74Å
251L96.7Very high96.9Very high14 Ų1449.7 Ų49.77%0.07324%0.243CC..EExtended strand (participates in β ladder)trans-113.3-33.4-173.2-62172.5000113F265 N267 L323L251-F265 HydrophobicContact CB-CD1 4.2Å; L251-F265 HydrophobicContact CD1-CD1 4.06Å; L251-F265 HydrophobicContact CD1-CE1 3.93Å; L251-F265 PolarHBondContact N-O 3.09Å; L251-N267 HydrophobicContact CD1-CB 4.11Å; L251-N267 HydrophobicContact CD2-CB 4.5Å; L251-N267 HydrophobicContact CG-CB 4.36Å; L251-L323 HydrophobicContact CD1-CD1 4.1Å; L251-L323 HydrophobicContact CD1-CD2 3.77Å; L251-L323 HydrophobicContact CD1-CG 3.6Å; L251-L323 HydrophobicContact CD2-CD2 4.38Å; L251-L323 HydrophobicContact CD2-CG 4.24Å
252C97.6Very high97Very high0 Ų044.7 Ų44.70%022%0.223CC..EExtended strand (participates in β ladder)trans-145136177-171.30000109.5T254 V264 F265 T326 V328C252-T254 PolarHBondContact SG-OG1 3.07Å; C252-T254 VanDerWaalsContact SG-OG1 3.4Å; C252-V264 CarbonylContact O-C 3.55Å; C252-V264 WeakPolarHBondContact O-CA 3.28Å; C252-F265 HydrophobicContact CB-CB 4.16Å; C252-F265 PolarHBondContact N-O 3.37Å; C252-F265 PolarHBondContact O-N 3.37Å; C252-T326 WeakPolarHBondContact CB-O 2.84Å; C252-V328 HydrophobicContact CB-CG2 4.43Å; C252-V328 PolarHBondContact SG-N 2.99Å
253L98.4Very high97.1Very high1 Ų142 Ų421%0.00521%0.211CC..EExtended strand (participates in β ladder)trans-115.2132.1169168.162.8000106.3L194 E196 I205 I207 F262 V263 V264L194-L253 HydrophobicContact CB-CB 4.22Å; L194-L253 HydrophobicContact CD1-CB 3.98Å; E196-L253 HydrophobicContact CB-CD2 3.73Å; E196-L253 HydrophobicContact CB-CG 3.89Å; E196-L253 HydrophobicContact CG-CB 4.11Å; E196-L253 HydrophobicContact CG-CD2 4.04Å; E196-L253 HydrophobicContact CG-CG 3.84Å; E196-L253 VanDerWaalsContact CG-O 3.29Å; E196-L253 WeakPolarHBondContact CG-O 3.38Å; I205-L253 HydrophobicContact CB-CD2 3.95Å; I205-L253 HydrophobicContact CG2-CD1 4.48Å; I205-L253 HydrophobicContact CG2-CD2 3.78Å; I207-L253 HydrophobicContact CD1-CB 4.34Å; I207-L253 HydrophobicContact CD1-CD1 4.29Å; I207-L253 HydrophobicContact CD1-CD2 4.15Å; I207-L253 HydrophobicContact CG1-CD2 4.27Å; L253-F262 HydrophobicContact CD1-CB 4.19Å; L253-F262 HydrophobicContact CD1-CD2 3.45Å; L253-F262 VanDerWaalsContact CD1-CD2 3.45Å; L253-F262 HydrophobicContact CD1-CE2 4.2Å; L253-F262 HydrophobicContact CD1-CG 4.17Å; L253-V263 WeakPolarHBondContact CA-O 3.44Å; L253-V264 HydrophobicContact CD1-CG2 3.98Å
254T98Very high97.1Very high18 Ų1842 Ų4211%0.1121%0.211CC..EExtended strand (participates in β ladder)trans-141129.2-179.2-610000109.3C252 F262 V263 V328 Y330C252-T254 PolarHBondContact SG-OG1 3.07Å; C252-T254 VanDerWaalsContact SG-OG1 3.4Å; T254-F262 CarbonylContact O-C 3.5Å; T254-F262 VanDerWaalsContact O-CA 3.29Å; T254-F262 WeakPolarHBondContact O-CA 3.31Å; T254-V263 PolarHBondContact N-O 3.04Å; T254-V263 PolarHBondContact O-N 3.34Å; T254-V328 WeakPolarHBondContact CG2-O 3.41Å; T254-V328 PolarHBondContact OG1-O 2.85Å; T254-Y330 HydrophobicContact CG2-CD2 3.69Å; T254-Y330 HydrophobicContact CG2-CE2 4.17Å
255I98.3Very high97.2Very high28 Ų2840 Ų4014%0.14420%0.198CC..EExtended strand (participates in β ladder)trans-102.1135.8-177.7-55.2175000108.7E196 N198 I205 F262E196-I255 HydrophobicContact CB-CD1 3.83Å; E196-I255 HydrophobicContact CB-CG1 4.22Å; N198-I255 HydrophobicContact CB-CD1 3.9Å; N198-I255 HydrophobicContact CB-CG2 4.3Å; I205-I255 HydrophobicContact CD1-CD1 4Å; I205-I255 HydrophobicContact CD1-CG1 4.39Å; I205-I255 HydrophobicContact CG1-CD1 4.48Å; I255-F262 HydrophobicContact CB-CB 4.42Å; I255-F262 HydrophobicContact CG1-CB 3.96Å
256R97.8Very high97.2Very high54 Ų5432.3 Ų32.320%0.20417%0.165CC..  trans-64.7142.7175.3-165.2169.975.3-176.714.4109.6D258 G259 E261 Y330 G334R256-D258 IonicContact CZ-OD1 3.75Å; R256-D258 IonicContact CZ-OD2 3.65Å; R256-D258 IonicContact NE-OD1 2.65Å; R256-D258 PolarHBondContact NE-OD1 2.78Å; R256-D258 IonicContact NE-OD2 3.57Å; R256-D258 PolarHBondContact NE-OD2 3.04Å; R256-D258 IonicContact NH2-OD1 3.82Å; R256-D258 PolarHBondContact NH2-OD1 3.32Å; R256-D258 IonicContact NH2-OD2 3.7Å; R256-D258 PolarHBondContact NH2-OD2 3.31Å; R256-D258 PolarHBondContact O-N 2.73Å; R256-G259 WeakPolarHBondContact O-CA 3.37Å; R256-G259 PolarHBondContact O-N 3.06Å; R256-E261 HydrophobicContact CB-CB 4.34Å; R256-E261 VanDerWaalsContact CB-O 3.29Å; R256-E261 WeakPolarHBondContact CB-O 3.43Å; R256-E261 PolarHBondContact N-O 3.32Å; R256-E261 IonicContact NH1-OE1 2.58Å; R256-Y330 HydrophobicContact CB-CD2 4.21Å; R256-Y330 HydrophobicContact CB-CE1 4.16Å; R256-Y330 HydrophobicContact CB-CE2 3.85Å; R256-Y330 HydrophobicContact CG-CD1 3.99Å; R256-Y330 HydrophobicContact CG-CD2 4.47Å; R256-Y330 HydrophobicContact CG-CE1 3.74Å; R256-Y330 HydrophobicContact CG-CE2 4.3Å; R256-Y330 HydrophobicContact CG-CG 4.33Å; R256-G334 WeakPolarHBondContact CD-O 3.22Å
257P95.9Very high97.2Very high60 Ų6033.2 Ų33.239%0.3916%0.164SC..THydrogen-bonded Turntrans-53.5-30.3-175.3-31.135.3000116.1G259 D331P257-G259 VanDerWaalsContact C-N 3.26Å; P257-G259 PolarHBondContact O-N 3.19Å; P257-D331 WeakPolarHBondContact CG-O 3.27Å
258D95.7Very high97.1Very high58 Ų5826.1 Ų26.131%0.3114%0.135SC..THydrogen-bonded Turntrans-81.1-2.7175.976.3-15000114.3R256 K260R256-D258 IonicContact CZ-OD1 3.75Å; R256-D258 IonicContact CZ-OD2 3.65Å; R256-D258 IonicContact NE-OD1 2.65Å; R256-D258 PolarHBondContact NE-OD1 2.78Å; R256-D258 IonicContact NE-OD2 3.57Å; R256-D258 PolarHBondContact NE-OD2 3.04Å; R256-D258 IonicContact NH2-OD1 3.82Å; R256-D258 PolarHBondContact NH2-OD1 3.32Å; R256-D258 IonicContact NH2-OD2 3.7Å; R256-D258 PolarHBondContact NH2-OD2 3.31Å; R256-D258 PolarHBondContact O-N 2.73Å; D258-K260 PolarHBondContact O-N 3.17Å; D258-K260 PolarHBondContact OD1-N 2.93Å; D258-K260 WeakPolarHBondContact OD2-CD 3.49Å
259G97Very high97Very high0 Ų025.7 Ų25.70%013%0.132CC..SBendtrans72.81.3178.800000115.8N198 F201 R256 P257 F276N198-G259 PolarHBondContact ND2-O 3.01Å; N198-G259 WeakPolarHBondContact OD1-CA 3.44Å; F201-G259 WeakPolarHBondContact CD2-O 3.34Å; F201-G259 WeakPolarHBondContact CE2-O 3.4Å; R256-G259 WeakPolarHBondContact O-CA 3.37Å; R256-G259 PolarHBondContact O-N 3.06Å; P257-G259 VanDerWaalsContact C-N 3.26Å; P257-G259 PolarHBondContact O-N 3.19Å; G259-F276 VanDerWaalsContact O-CB 3.25Å; G259-F276 WeakPolarHBondContact O-CB 3.42Å; G259-F276 WeakPolarHBondContact O-CG 3.26Å
260K97.3Very high97.2Very high122 Ų12225.9 Ų25.953%0.5313%0.129SC..SBendtrans-84.5-15.8-170.6-63.5-177.3-170162.50114F201 D258 F276F201-K260 HydrophobicContact CE2-CG 4.29Å; F201-K260 HydrophobicContact CZ-CG 4.44Å; D258-K260 PolarHBondContact O-N 3.17Å; D258-K260 PolarHBondContact OD1-N 2.93Å; D258-K260 WeakPolarHBondContact OD2-CD 3.49Å; K260-F276 WeakPolarHBondContact O-CB 3.16Å; K260-F276 PolarHBondContact O-N 2.77Å
261E97.8Very high97.2Very high19 Ų1925.7 Ų25.79%0.08913%0.128CC..EExtended strand (participates in β ladder)trans-141.9146.3-178.8-174.4175.568.100109.3R256 F273 Y274 T282 Y330R256-E261 HydrophobicContact CB-CB 4.34Å; R256-E261 VanDerWaalsContact CB-O 3.29Å; R256-E261 WeakPolarHBondContact CB-O 3.43Å; R256-E261 PolarHBondContact N-O 3.32Å; R256-E261 IonicContact NH1-OE1 2.58Å; E261-F273 HydrophobicContact CG-CB 4.48Å; E261-F273 HydrophobicContact CG-CD1 4.39Å; E261-Y274 CarbonylContact C-O 3.59Å; E261-Y274 VanDerWaalsContact CA-O 3.26Å; E261-Y274 WeakPolarHBondContact CA-O 3.2Å; E261-Y274 WeakPolarHBondContact CG-O 3.46Å; E261-T282 PolarHBondContact OE2-OG1 3.18Å; E261-Y330 PolarHBondContact OE1-OH 3.27Å
262F98.4Very high97.3Very high0 Ų025.5 Ų25.50%013%0.126CC..EExtended strand (participates in β ladder)trans-133.115516867.6-85.5000110I205 I213 Y215 L240 L253 T254 I255 V264 Y274 F276I205-F262 HydrophobicContact CD1-CB 4.36Å; I205-F262 HydrophobicContact CD1-CD1 3.78Å; I205-F262 HydrophobicContact CD1-CD2 4.41Å; I205-F262 HydrophobicContact CD1-CE1 4.14Å; I205-F262 HydrophobicContact CD1-CG 3.92Å; I213-F262 HydrophobicContact CD1-CE2 4.36Å; Y215-F262 HydrophobicContact CE1-CE1 4.34Å; Y215-F262 HydrophobicContact CE1-CZ 4.43Å; Y215-F262 WeakPolarHBondContact OH-CE1 3.33Å; L240-F262 HydrophobicContact CD2-CZ 4.12Å; L253-F262 HydrophobicContact CD1-CB 4.19Å; L253-F262 HydrophobicContact CD1-CD2 3.45Å; L253-F262 VanDerWaalsContact CD1-CD2 3.45Å; L253-F262 HydrophobicContact CD1-CE2 4.2Å; L253-F262 HydrophobicContact CD1-CG 4.17Å; T254-F262 CarbonylContact O-C 3.5Å; T254-F262 VanDerWaalsContact O-CA 3.29Å; T254-F262 WeakPolarHBondContact O-CA 3.31Å; I255-F262 HydrophobicContact CB-CB 4.42Å; I255-F262 HydrophobicContact CG1-CB 3.96Å; F262-V264 HydrophobicContact CD2-CG2 4.11Å; F262-V264 HydrophobicContact CE2-CG2 4.04Å; F262-Y274 HydrophobicContact CD2-CD2 4.1Å; F262-Y274 HydrophobicContact CD2-CG 4.34Å; F262-Y274 HydrophobicContact CE1-CG 4.09Å; F262-Y274 HydrophobicContact CE2-CD1 4.39Å; F262-Y274 AromaticContact CE2-CD2 3.54Å; F262-Y274 HydrophobicContact CE2-CD2 3.54Å; F262-Y274 HydrophobicContact CE2-CE2 4.31Å; F262-Y274 AromaticContact CE2-CG 3.6Å; F262-Y274 HydrophobicContact CE2-CG 3.6Å; F262-Y274 HydrophobicContact CZ-CD1 4Å; F262-Y274 AromaticContact CZ-CD2 3.94Å; F262-Y274 HydrophobicContact CZ-CD2 3.94Å; F262-Y274 AromaticContact CZ-CG 3.46Å; F262-Y274 HydrophobicContact CZ-CG 3.46Å; F262-Y274 VanDerWaalsContact CZ-CG 3.46Å; F262-Y274 PolarHBondContact N-O 3.11Å; F262-Y274 PolarHBondContact O-N 3.09Å; F262-F276 HydrophobicContact CD1-CB 4.46Å; F262-F276 HydrophobicContact CD1-CD2 4.43Å
263V98.5Very high97.3Very high1 Ų125.5 Ų25.51%0.00613%0.126CC..EExtended strand (participates in β ladder)trans-122.4133.7-176.2-171.60000108.9L253 T254 L271 R272 F273 Y330 L337L253-V263 WeakPolarHBondContact CA-O 3.44Å; T254-V263 PolarHBondContact N-O 3.04Å; T254-V263 PolarHBondContact O-N 3.34Å; V263-L271 HydrophobicContact CG1-CB 4.08Å; V263-L271 HydrophobicContact CG1-CD2 3.76Å; V263-R272 WeakPolarHBondContact CA-O 3.4Å; V263-F273 HydrophobicContact CG1-CD1 4.48Å; V263-F273 HydrophobicContact CG1-CD2 4.21Å; V263-F273 HydrophobicContact CG1-CE1 4.37Å; V263-F273 HydrophobicContact CG1-CE2 4.09Å; V263-F273 HydrophobicContact CG1-CG 4.4Å; V263-F273 HydrophobicContact CG1-CZ 4.18Å; V263-F273 HydrophobicContact CG2-CD1 3.33Å; V263-F273 HydrophobicContact CG2-CD2 4.45Å; V263-F273 HydrophobicContact CG2-CE1 3.41Å; V263-F273 VanDerWaalsContact CG2-CE1 3.41Å; V263-F273 HydrophobicContact CG2-CG 3.89Å; V263-F273 HydrophobicContact CG2-CZ 4.05Å; V263-Y330 HydrophobicContact CG2-CE2 4Å; V263-Y330 WeakPolarHBondContact CG2-OH 3.4Å; V263-L337 HydrophobicContact CG1-CD2 4.25Å; V263-L337 HydrophobicContact CG2-CD1 4.44Å; V263-L337 HydrophobicContact CG2-CD2 4.35Å
264V98.6Very high97.3Very high0 Ų025.4 Ų25.40%013%0.125CC..EExtended strand (participates in β ladder)trans-111.3122.9171-175.20000108.8I207 L243 P250 C252 L253 F262 L271 R272 Y274I207-V264 HydrophobicContact CD1-CG1 4.23Å; I207-V264 HydrophobicContact CD1-CG2 3.7Å; L243-V264 HydrophobicContact CD1-CG1 3.97Å; L243-V264 HydrophobicContact CD2-CG1 4.33Å; P250-V264 HydrophobicContact CB-CG1 3.74Å; C252-V264 CarbonylContact O-C 3.55Å; C252-V264 WeakPolarHBondContact O-CA 3.28Å; L253-V264 HydrophobicContact CD1-CG2 3.98Å; F262-V264 HydrophobicContact CD2-CG2 4.11Å; F262-V264 HydrophobicContact CE2-CG2 4.04Å; V264-L271 WeakPolarHBondContact O-CA 3.44Å; V264-R272 PolarHBondContact N-O 3.5Å; V264-R272 PolarHBondContact O-N 2.95Å; V264-Y274 HydrophobicContact CB-CE2 4.31Å; V264-Y274 HydrophobicContact CG2-CD2 4.29Å; V264-Y274 HydrophobicContact CG2-CE2 4Å
265F98Very high97.3Very high7 Ų729 Ų293%0.03114%0.139CC..EExtended strand (participates in β ladder)trans-94.7135.7166.4-174.6-115.6000109.4L251 C252 K270 L271 T326 V328L251-F265 HydrophobicContact CB-CD1 4.2Å; L251-F265 HydrophobicContact CD1-CD1 4.06Å; L251-F265 HydrophobicContact CD1-CE1 3.93Å; L251-F265 PolarHBondContact N-O 3.09Å; C252-F265 HydrophobicContact CB-CB 4.16Å; C252-F265 PolarHBondContact N-O 3.37Å; C252-F265 PolarHBondContact O-N 3.37Å; F265-K270 WeakPolarHBondContact CA-O 3.28Å; F265-L271 HydrophobicContact CB-CD2 3.82Å; F265-L271 HydrophobicContact CD2-CD2 3.67Å; F265-L271 HydrophobicContact CD2-CG 3.91Å; F265-L271 HydrophobicContact CG-CD2 4.14Å; F265-T326 HydrophobicContact CD1-CG2 3.87Å; F265-T326 HydrophobicContact CE1-CG2 3.71Å; F265-V328 HydrophobicContact CB-CG2 3.97Å; F265-V328 HydrophobicContact CG-CG2 4.35Å
266S97.1Very high97.3Very high0 Ų027.7 Ų27.70%013%0.133CC..EExtended strand (participates in β ladder)trans-129.4165.4-174.7-51.50000112.1V249 D268 G269 K270V249-S266 CarbonylContact O-C 3.52Å; V249-S266 VanDerWaalsContact O-CA 3.32Å; V249-S266 WeakPolarHBondContact O-CA 3.46Å; V249-S266 WeakPolarHBondContact O-CB 3.34Å; S266-D268 WeakPolarHBondContact CB-OD1 3.38Å; S266-D268 PolarHBondContact O-N 2.93Å; S266-G269 PolarHBondContact O-N 3.37Å; S266-K270 PolarHBondContact N-O 3.31Å
267N95.3Very high97.3Very high58 Ų5826 Ų2631%0.3113%0.129SC..THydrogen-bonded Turntrans-68.5-0.8-17774.5-28.2000115.3V249 L251 G269 Y317 L323V249-N267 HydrophobicContact CB-CB 4.39Å; V249-N267 PolarHBondContact N-OD1 3.02Å; V249-N267 PolarHBondContact O-N 3.38Å; V249-N267 PolarHBondContact O-OD1 3.25Å; L251-N267 HydrophobicContact CD1-CB 4.11Å; L251-N267 HydrophobicContact CD2-CB 4.5Å; L251-N267 HydrophobicContact CG-CB 4.36Å; N267-G269 VanDerWaalsContact C-N 3.27Å; N267-Y317 WeakPolarHBondContact O-CD1 3.48Å; N267-Y317 WeakPolarHBondContact O-CE1 3.34Å; N267-L323 HydrophobicContact CB-CD2 4.18Å
268D94.7Very high97.3Very high43 Ų4325.2 Ų25.223%0.2312%0.122CC..THydrogen-bonded Turntrans-87.2216767.4-19.9000112.8V248 S266 K270 R272V248-D268 HydrophobicContact CG1-CB 3.83Å; S266-D268 WeakPolarHBondContact CB-OD1 3.38Å; S266-D268 PolarHBondContact O-N 2.93Å; D268-K270 VanDerWaalsContact C-N 3.33Å; D268-K270 PolarHBondContact OD1-N 3.42Å; D268-K270 WeakPolarHBondContact OD2-CD 3.45Å; D268-R272 IonicContact OD1-CZ 3.88Å; D268-R272 IonicContact OD1-NH1 2.76Å; D268-R272 PolarHBondContact OD1-NH1 3.41Å; D268-R272 VanDerWaalsContact OD1-NH1 3.09Å; D268-R272 IonicContact OD1-NH2 3.38Å; D268-R272 IonicContact OD2-CZ 2.77Å; D268-R272 IonicContact OD2-NH1 3.55Å; D268-R272 PolarHBondContact OD2-NH1 3.33Å; D268-R272 IonicContact OD2-NH2 2.76Å; D268-R272 PolarHBondContact OD2-NH2 2.94Å
269G94.7Very high97.4Very high0 Ų022.4 Ų22.40%011%0.107CC..SBendtrans78.114.9-178.900000113.4S266 N267 E287 G288 Y317S266-G269 PolarHBondContact O-N 3.37Å; N267-G269 VanDerWaalsContact C-N 3.27Å; G269-E287 CarbonylContact O-C 3.52Å; G269-E287 VanDerWaalsContact O-C 3.26Å; G269-E287 WeakPolarHBondContact O-CA 3.3Å; G269-E287 VanDerWaalsContact O-CB 3.24Å; G269-E287 WeakPolarHBondContact O-CB 3.37Å; G269-E287 PolarHBondContact O-N 3.25Å; G269-G288 PolarHBondContact O-N 3.42Å; G269-Y317 WeakPolarHBondContact CA-OH 3.34Å
270K97.3Very high97.4Very high57 Ų5727.1 Ų27.125%0.24813%0.127CC..EExtended strand (participates in β ladder)trans-103.3142.2-178.1-58-172.2-1761790112.7F265 S266 D268 V284 I285 D286F265-K270 WeakPolarHBondContact CA-O 3.28Å; S266-K270 PolarHBondContact N-O 3.31Å; D268-K270 VanDerWaalsContact C-N 3.33Å; D268-K270 PolarHBondContact OD1-N 3.42Å; D268-K270 WeakPolarHBondContact OD2-CD 3.45Å; K270-V284 HydrophobicContact CB-CG1 4.19Å; K270-V284 HydrophobicContact CD-CG1 4.12Å; K270-I285 CarbonylContact C-O 3.47Å; K270-I285 VanDerWaalsContact CA-O 3.29Å; K270-I285 WeakPolarHBondContact CA-O 3.37Å; K270-D286 WeakPolarHBondContact CE-OD2 3.38Å; K270-D286 HydrophobicContact CG-CB 4.46Å; K270-D286 IonicContact NZ-OD2 3.29Å
271L98Very high97.5Very high0 Ų022.8 Ų22.80%011%0.11CC..EExtended strand (participates in β ladder)trans-98.1119.1167.3-67.6161.5000108.7V263 V264 F265 F273 V284 I285 V328 L337 Y339V263-L271 HydrophobicContact CG1-CB 4.08Å; V263-L271 HydrophobicContact CG1-CD2 3.76Å; V264-L271 WeakPolarHBondContact O-CA 3.44Å; F265-L271 HydrophobicContact CB-CD2 3.82Å; F265-L271 HydrophobicContact CD2-CD2 3.67Å; F265-L271 HydrophobicContact CD2-CG 3.91Å; F265-L271 HydrophobicContact CG-CD2 4.14Å; L271-F273 HydrophobicContact CB-CE2 3.89Å; L271-V284 CarbonylContact O-C 3.52Å; L271-V284 VanDerWaalsContact O-CA 3.31Å; L271-V284 WeakPolarHBondContact O-CA 3.38Å; L271-I285 HydrophobicContact CB-CB 4.23Å; L271-I285 HydrophobicContact CD1-CG2 4.34Å; L271-I285 PolarHBondContact N-O 3.03Å; L271-I285 PolarHBondContact O-N 3.07Å; L271-V328 HydrophobicContact CD2-CG1 4.37Å; L271-V328 HydrophobicContact CD2-CG2 3.99Å; L271-L337 HydrophobicContact CD1-CD2 4.29Å; L271-L337 HydrophobicContact CD2-CD2 4.49Å; L271-Y339 HydrophobicContact CD1-CD1 4Å; L271-Y339 HydrophobicContact CD1-CD2 3.84Å; L271-Y339 HydrophobicContact CD1-CE1 3.86Å; L271-Y339 HydrophobicContact CD1-CE2 3.69Å; L271-Y339 HydrophobicContact CD1-CG 4Å
272R98.2Very high97.4Very high9 Ų925.1 Ų25.13%0.03413%0.125CC..EExtended strand (participates in β ladder)trans-109.5120.4177-66.1170.6176.878.13.1109.2V263 V264 D268 Y274 V284V263-R272 WeakPolarHBondContact CA-O 3.4Å; V264-R272 PolarHBondContact N-O 3.5Å; V264-R272 PolarHBondContact O-N 2.95Å; D268-R272 IonicContact OD1-CZ 3.88Å; D268-R272 IonicContact OD1-NH1 2.76Å; D268-R272 PolarHBondContact OD1-NH1 3.41Å; D268-R272 VanDerWaalsContact OD1-NH1 3.09Å; D268-R272 IonicContact OD1-NH2 3.38Å; D268-R272 IonicContact OD2-CZ 2.77Å; D268-R272 IonicContact OD2-NH1 3.55Å; D268-R272 PolarHBondContact OD2-NH1 3.33Å; D268-R272 IonicContact OD2-NH2 2.76Å; D268-R272 PolarHBondContact OD2-NH2 2.94Å; R272-Y274 HydrophobicContact CB-CD2 4.39Å; R272-Y274 HydrophobicContact CB-CE2 3.63Å; R272-Y274 WeakPolarHBondContact O-CD2 3.35Å; R272-V284 HydrophobicContact CG-CG1 4.15Å; R272-V284 HydrophobicContact CG-CG2 4.06Å
273F98.4Very high97.2Very high0 Ų025.9 Ų25.90%013%0.129CC..EExtended strand (participates in β ladder)trans-97.9126.7-178.6-68-111.4000108.9E261 V263 L271 I281 T282 K283 I285 L337 L348E261-F273 HydrophobicContact CG-CB 4.48Å; E261-F273 HydrophobicContact CG-CD1 4.39Å; V263-F273 HydrophobicContact CG1-CD1 4.48Å; V263-F273 HydrophobicContact CG1-CD2 4.21Å; V263-F273 HydrophobicContact CG1-CE1 4.37Å; V263-F273 HydrophobicContact CG1-CE2 4.09Å; V263-F273 HydrophobicContact CG1-CG 4.4Å; V263-F273 HydrophobicContact CG1-CZ 4.18Å; V263-F273 HydrophobicContact CG2-CD1 3.33Å; V263-F273 HydrophobicContact CG2-CD2 4.45Å; V263-F273 HydrophobicContact CG2-CE1 3.41Å; V263-F273 VanDerWaalsContact CG2-CE1 3.41Å; V263-F273 HydrophobicContact CG2-CG 3.89Å; V263-F273 HydrophobicContact CG2-CZ 4.05Å; L271-F273 HydrophobicContact CB-CE2 3.89Å; F273-I281 CarbonylContact O-C 3.57Å; F273-I281 WeakPolarHBondContact O-CA 3.34Å; F273-T282 WeakPolarHBondContact CB-OG1 3.29Å; F273-T282 PolarHBondContact O-N 3.2Å; F273-T282 PolarHBondContact O-OG1 3.23Å; F273-K283 HydrophobicContact CB-CG 3.66Å; F273-K283 HydrophobicContact CD1-CD 4.39Å; F273-K283 HydrophobicContact CD1-CG 4.29Å; F273-K283 HydrophobicContact CD2-CD 4.07Å; F273-K283 VanDerWaalsContact CD2-CE 3.5Å; F273-K283 HydrophobicContact CD2-CG 3.49Å; F273-K283 VanDerWaalsContact CD2-CG 3.49Å; F273-K283 HydrophobicContact CE2-CD 4.32Å; F273-K283 HydrophobicContact CE2-CG 4.19Å; F273-K283 HydrophobicContact CG-CD 4.1Å; F273-K283 HydrophobicContact CG-CG 3.56Å; F273-K283 VanDerWaalsContact CZ-CE 3.4Å; F273-K283 PolarHBondContact N-O 2.95Å; F273-I285 HydrophobicContact CE2-CD1 3.87Å; F273-I285 HydrophobicContact CE2-CG1 4.35Å; F273-I285 HydrophobicContact CZ-CD1 4.21Å; F273-L337 HydrophobicContact CE1-CD2 3.94Å; F273-L337 HydrophobicContact CE2-CD2 4.48Å; F273-L337 HydrophobicContact CZ-CD2 3.51Å; F273-L348 HydrophobicContact CZ-CD2 3.98Å
274Y98.4Very high97.2Very high0 Ų026.5 Ų26.50%013%0.132CC..EExtended strand (participates in β ladder)trans-116.6130.5-179-67.8-98.6000109.6I213 D239 L240 E261 F262 V264 R272 F276 K280 I281I213-Y274 HydrophobicContact CD1-CE1 4.32Å; I213-Y274 HydrophobicContact CD1-CE2 4.5Å; D239-Y274 HydrophobicContact CB-CE1 4.42Å; L240-Y274 HydrophobicContact CD2-CD1 4.23Å; L240-Y274 HydrophobicContact CD2-CE1 4.45Å; E261-Y274 CarbonylContact C-O 3.59Å; E261-Y274 VanDerWaalsContact CA-O 3.26Å; E261-Y274 WeakPolarHBondContact CA-O 3.2Å; E261-Y274 WeakPolarHBondContact CG-O 3.46Å; F262-Y274 HydrophobicContact CD2-CD2 4.1Å; F262-Y274 HydrophobicContact CD2-CG 4.34Å; F262-Y274 HydrophobicContact CE1-CG 4.09Å; F262-Y274 HydrophobicContact CE2-CD1 4.39Å; F262-Y274 AromaticContact CE2-CD2 3.54Å; F262-Y274 HydrophobicContact CE2-CD2 3.54Å; F262-Y274 HydrophobicContact CE2-CE2 4.31Å; F262-Y274 AromaticContact CE2-CG 3.6Å; F262-Y274 HydrophobicContact CE2-CG 3.6Å; F262-Y274 HydrophobicContact CZ-CD1 4Å; F262-Y274 AromaticContact CZ-CD2 3.94Å; F262-Y274 HydrophobicContact CZ-CD2 3.94Å; F262-Y274 AromaticContact CZ-CG 3.46Å; F262-Y274 HydrophobicContact CZ-CG 3.46Å; F262-Y274 VanDerWaalsContact CZ-CG 3.46Å; F262-Y274 PolarHBondContact N-O 3.11Å; F262-Y274 PolarHBondContact O-N 3.09Å; V264-Y274 HydrophobicContact CB-CE2 4.31Å; V264-Y274 HydrophobicContact CG2-CD2 4.29Å; V264-Y274 HydrophobicContact CG2-CE2 4Å; R272-Y274 HydrophobicContact CB-CD2 4.39Å; R272-Y274 HydrophobicContact CB-CE2 3.63Å; R272-Y274 WeakPolarHBondContact O-CD2 3.35Å; Y274-F276 PolarHBondContact O-N 3.25Å; Y274-K280 CarbonylContact C-O 3.55Å; Y274-K280 WeakPolarHBondContact CA-O 3.36Å; Y274-I281 HydrophobicContact CD1-CG1 3.69Å; Y274-I281 HydrophobicContact CE1-CD1 3.84Å; Y274-I281 HydrophobicContact CE1-CG1 3.35Å; Y274-I281 HydrophobicContact CE2-CG1 4.23Å; Y274-I281 HydrophobicContact CG-CG1 4.27Å
275K97.9Very high97.1Very high93 Ų9326.5 Ų26.540%0.40413%0.132SC..EExtended strand (participates in β ladder)trans-72.5119.4167.5-177.8177.4-178.1-169.70108.4S277 N278 G279 K280 T282K275-S277 WeakPolarHBondContact CE-OG 3.3Å; K275-S277 PolarHBondContact O-N 3.5Å; K275-N278 WeakPolarHBondContact CB-OD1 3.46Å; K275-N278 PolarHBondContact O-N 3.24Å; K275-G279 WeakPolarHBondContact O-CA 3.45Å; K275-G279 PolarHBondContact O-N 3.06Å; K275-K280 PolarHBondContact N-O 2.71Å; K275-T282 HydrophobicContact CB-CG2 3.79Å
276F98.1Very high96.9Very high0 Ų028 Ų280%014%0.14CC..THydrogen-bonded Turntrans-55.2-42.7-174.8176.4-99.5000112.1N198 F201 T203 I205 Y215 V230 G259 K260 F262 Y274 N278N198-F276 HydrophobicContact CB-CE2 4.23Å; N198-F276 WeakPolarHBondContact ND2-CD2 3.44Å; N198-F276 VanDerWaalsContact ND2-CE2 3.27Å; N198-F276 WeakPolarHBondContact ND2-CE2 3.49Å; F201-F276 HydrophobicContact CB-CE1 3.61Å; F201-F276 HydrophobicContact CB-CZ 3.87Å; F201-F276 HydrophobicContact CD1-CE1 4.33Å; F201-F276 AromaticContact CD2-CD1 3.78Å; F201-F276 HydrophobicContact CD2-CD1 3.78Å; F201-F276 AromaticContact CD2-CE1 3.74Å; F201-F276 HydrophobicContact CD2-CE1 3.74Å; F201-F276 HydrophobicContact CE2-CD1 4.17Å; F201-F276 HydrophobicContact CG-CD1 4.12Å; F201-F276 AromaticContact CG-CE1 3.63Å; F201-F276 HydrophobicContact CG-CE1 3.63Å; F201-F276 HydrophobicContact CG-CZ 4.35Å; T203-F276 HydrophobicContact CG2-CE2 4.02Å; T203-F276 HydrophobicContact CG2-CZ 3.85Å; I205-F276 HydrophobicContact CD1-CD2 3.95Å; I205-F276 HydrophobicContact CD1-CE2 4.01Å; I205-F276 HydrophobicContact CG1-CE2 4.31Å; Y215-F276 HydrophobicContact CD2-CE2 4.09Å; Y215-F276 HydrophobicContact CD2-CZ 4.3Å; Y215-F276 AromaticContact CE2-CD2 3.78Å; Y215-F276 HydrophobicContact CE2-CD2 3.78Å; Y215-F276 AromaticContact CE2-CE2 3.45Å; Y215-F276 HydrophobicContact CE2-CE2 3.45Å; Y215-F276 VanDerWaalsContact CE2-CE2 3.45Å; Y215-F276 HydrophobicContact CE2-CG 4.47Å; Y215-F276 AromaticContact CE2-CZ 3.88Å; Y215-F276 HydrophobicContact CE2-CZ 3.88Å; Y215-F276 AromaticContact CZ-CD2 3.74Å; Y215-F276 AromaticContact CZ-CE2 3.74Å; Y215-F276 WeakPolarHBondContact OH-CD2 3.5Å; Y215-F276 PolarHBondContact OH-O 2.97Å; V230-F276 HydrophobicContact CG2-CE1 3.9Å; V230-F276 HydrophobicContact CG2-CZ 4.07Å; G259-F276 VanDerWaalsContact O-CB 3.25Å; G259-F276 WeakPolarHBondContact O-CB 3.42Å; G259-F276 WeakPolarHBondContact O-CG 3.26Å; K260-F276 WeakPolarHBondContact O-CB 3.16Å; K260-F276 PolarHBondContact O-N 2.77Å; F262-F276 HydrophobicContact CD1-CB 4.46Å; F262-F276 HydrophobicContact CD1-CD2 4.43Å; Y274-F276 PolarHBondContact O-N 3.25Å; F276-N278 PolarHBondContact O-N 3.35Å
277S97.5Very high96.8Very high19 Ų1928.2 Ų28.213%0.13314%0.141CC..THydrogen-bonded Turntrans-71-30.7-169.786.60000114.8G229 D231 W232 K275G229-S277 WeakPolarHBondContact O-CA 3.26Å; G229-S277 WeakPolarHBondContact O-CB 3.22Å; D231-S277 PolarHBondContact N-O 2.91Å; D231-S277 WeakPolarHBondContact OD2-CB 3.23Å; D231-S277 PolarHBondContact OD2-OG 3.29Å; W232-S277 VanDerWaalsContact CD1-O 3.22Å; K275-S277 WeakPolarHBondContact CE-OG 3.3Å; K275-S277 PolarHBondContact O-N 3.5Å
278N96.7Very high96.8Very high43 Ų4325.9 Ų25.923%0.2313%0.131CC..THydrogen-bonded Turntrans-119.51.2-179.968.57000113.6W232 T238 K275 F276 K280W232-N278 VanDerWaalsContact CD1-C 3.49Å; T238-N278 WeakPolarHBondContact CG2-O 3.44Å; K275-N278 WeakPolarHBondContact CB-OD1 3.46Å; K275-N278 PolarHBondContact O-N 3.24Å; F276-N278 PolarHBondContact O-N 3.35Å; N278-K280 HydrophobicContact CB-CG 4.48Å; N278-K280 PolarHBondContact O-N 2.82Å; N278-K280 VanDerWaalsContact O-N 3.13Å; N278-K280 WeakPolarHBondContact OD1-CB 3.37Å; N278-K280 PolarHBondContact OD1-N 3.18Å; N278-K280 VanDerWaalsContact OD1-N 3.12Å
279G96.9Very high96.7Very high0 Ų025.9 Ų25.90%013%0.131CC..THydrogen-bonded Turntrans62.416.2179.900000114.7D239 K275D239-G279 PolarHBondContact N-O 3.33Å; K275-G279 WeakPolarHBondContact O-CA 3.45Å; K275-G279 PolarHBondContact O-N 3.06Å
280K98.2Very high96.6Very high98 Ų9833.2 Ų33.243%0.42616%0.163SC..EExtended strand (participates in β ladder)trans-93.1146.1-177.8-64.1-172.2177.9-1790112E237 D239 Y274 K275 N278 T282E237-K280 WeakPolarHBondContact O-CE 3.18Å; D239-K280 VanDerWaalsContact OD2-CA 3.28Å; D239-K280 WeakPolarHBondContact OD2-CA 3.25Å; D239-K280 WeakPolarHBondContact OD2-CB 3.41Å; Y274-K280 CarbonylContact C-O 3.55Å; Y274-K280 WeakPolarHBondContact CA-O 3.36Å; K275-K280 PolarHBondContact N-O 2.71Å; N278-K280 HydrophobicContact CB-CG 4.48Å; N278-K280 PolarHBondContact O-N 2.82Å; N278-K280 VanDerWaalsContact O-N 3.13Å; N278-K280 WeakPolarHBondContact OD1-CB 3.37Å; N278-K280 PolarHBondContact OD1-N 3.18Å; N278-K280 VanDerWaalsContact OD1-N 3.12Å; K280-T282 PolarHBondContact O-N 3.5Å
281I97.9Very high96.4Very high32 Ų3231.2 Ų31.216%0.16416%0.155CC..EExtended strand (participates in β ladder)trans-73.3126.1174.7-68.4170.8000109.1D239 E242 F273 Y274 V284D239-I281 HydrophobicContact CB-CB 4.35Å; D239-I281 HydrophobicContact CB-CD1 4.03Å; D239-I281 HydrophobicContact CB-CG1 3.83Å; D239-I281 PolarHBondContact OD2-N 2.9Å; E242-I281 HydrophobicContact CB-CD1 3.68Å; E242-I281 HydrophobicContact CG-CD1 3.54Å; F273-I281 CarbonylContact O-C 3.57Å; F273-I281 WeakPolarHBondContact O-CA 3.34Å; Y274-I281 HydrophobicContact CD1-CG1 3.69Å; Y274-I281 HydrophobicContact CE1-CD1 3.84Å; Y274-I281 HydrophobicContact CE1-CG1 3.35Å; Y274-I281 HydrophobicContact CE2-CG1 4.23Å; Y274-I281 HydrophobicContact CG-CG1 4.27Å; I281-V284 HydrophobicContact CG2-CG2 3.65Å
282T96.2Very high96.2Very high67 Ų6731.2 Ų31.241%0.41116%0.155SC..EExtended strand (participates in β ladder)trans-92.8-35.6177.8560000111.8E261 F273 K275 K280E261-T282 PolarHBondContact OE2-OG1 3.18Å; F273-T282 WeakPolarHBondContact CB-OG1 3.29Å; F273-T282 PolarHBondContact O-N 3.2Å; F273-T282 PolarHBondContact O-OG1 3.23Å; K275-T282 HydrophobicContact CB-CG2 3.79Å; K280-T282 PolarHBondContact O-N 3.5Å
283K95.4Very high95.9Very high17 Ų1734.7 Ų34.77%0.07418%0.177CC..EExtended strand (participates in β ladder)trans-160.5158.2177.462.6-178.8-178.4-172.30111.5L18 F273 V350 N353L18-K283 HydrophobicContact CD2-CB 4.28Å; F273-K283 HydrophobicContact CB-CG 3.66Å; F273-K283 HydrophobicContact CD1-CD 4.39Å; F273-K283 HydrophobicContact CD1-CG 4.29Å; F273-K283 HydrophobicContact CD2-CD 4.07Å; F273-K283 VanDerWaalsContact CD2-CE 3.5Å; F273-K283 HydrophobicContact CD2-CG 3.49Å; F273-K283 VanDerWaalsContact CD2-CG 3.49Å; F273-K283 HydrophobicContact CE2-CD 4.32Å; F273-K283 HydrophobicContact CE2-CG 4.19Å; F273-K283 HydrophobicContact CG-CD 4.1Å; F273-K283 HydrophobicContact CG-CG 3.56Å; F273-K283 VanDerWaalsContact CZ-CE 3.4Å; F273-K283 PolarHBondContact N-O 2.95Å; K283-V350 PolarHBondContact NZ-O 2.6Å; K283-N353 VanDerWaalsContact CD-OD1 3.23Å; K283-N353 WeakPolarHBondContact CD-OD1 3.46Å; K283-N353 PolarHBondContact NZ-OD1 3.21Å
284V97.1Very high95.6Very high13 Ų1341.2 Ų41.28%0.07921%0.207CC..EExtended strand (participates in β ladder)trans-130.5131.7172.6-177.60000109.2S19 K270 L271 R272 I281S19-V284 PolarHBondContact N-O 3.08Å; S19-V284 VanDerWaalsContact N-O 3.16Å; S19-V284 VanDerWaalsContact OG-CB 3.3Å; S19-V284 WeakPolarHBondContact OG-CB 3.49Å; S19-V284 WeakPolarHBondContact OG-CG1 3.4Å; K270-V284 HydrophobicContact CB-CG1 4.19Å; K270-V284 HydrophobicContact CD-CG1 4.12Å; L271-V284 CarbonylContact O-C 3.52Å; L271-V284 VanDerWaalsContact O-CA 3.31Å; L271-V284 WeakPolarHBondContact O-CA 3.38Å; R272-V284 HydrophobicContact CG-CG1 4.15Å; R272-V284 HydrophobicContact CG-CG2 4.06Å; I281-V284 HydrophobicContact CG2-CG2 3.65Å
285I96.2Very high95.1Very high0 Ų041.7 Ų41.70%021%0.21CC..EExtended strand (participates in β ladder)trans-113.6127.7176.5-70.4172000108.4P16 L18 K270 L271 F273 E287 L348P16-I285 HydrophobicContact CB-CB 4.47Å; P16-I285 HydrophobicContact CB-CD1 4.42Å; P16-I285 HydrophobicContact CB-CG1 4.29Å; P16-I285 HydrophobicContact CB-CG2 3.52Å; P16-I285 HydrophobicContact CG-CD1 3.95Å; P16-I285 HydrophobicContact CG-CG1 4.27Å; P16-I285 HydrophobicContact CG-CG2 4.17Å; L18-I285 HydrophobicContact CD2-CG1 4.23Å; K270-I285 CarbonylContact C-O 3.47Å; K270-I285 VanDerWaalsContact CA-O 3.29Å; K270-I285 WeakPolarHBondContact CA-O 3.37Å; L271-I285 HydrophobicContact CB-CB 4.23Å; L271-I285 HydrophobicContact CD1-CG2 4.34Å; L271-I285 PolarHBondContact N-O 3.03Å; L271-I285 PolarHBondContact O-N 3.07Å; F273-I285 HydrophobicContact CE2-CD1 3.87Å; F273-I285 HydrophobicContact CE2-CG1 4.35Å; F273-I285 HydrophobicContact CZ-CD1 4.21Å; I285-E287 HydrophobicContact CG2-CG 4.02Å; I285-L348 HydrophobicContact CD1-CD1 4.22Å; I285-L348 HydrophobicContact CD1-CD2 3.31Å; I285-L348 HydrophobicContact CD1-CG 4.41Å
286D95.5Very high94.5Very high38 Ų3840.2 Ų40.220%0.20320%0.204CC..EExtended strand (participates in β ladder)trans-96.1107.8179.5-164.3-24.6000111.1K270 G288 N291K270-D286 WeakPolarHBondContact CE-OD2 3.38Å; K270-D286 HydrophobicContact CG-CB 4.46Å; K270-D286 IonicContact NZ-OD2 3.29Å; D286-G288 WeakPolarHBondContact OD1-CA 3.12Å; D286-G288 PolarHBondContact OD1-N 2.97Å; D286-N291 PolarHBondContact O-ND2 3.4Å
287E95.3Very high93.9Very high5 Ų548.7 Ų48.72%0.02324%0.244CC..  trans-106.822171.5-60-67.517700111.1G269 I285 Y292 Y339 T341 K346G269-E287 CarbonylContact O-C 3.52Å; G269-E287 VanDerWaalsContact O-C 3.26Å; G269-E287 WeakPolarHBondContact O-CA 3.3Å; G269-E287 VanDerWaalsContact O-CB 3.24Å; G269-E287 WeakPolarHBondContact O-CB 3.37Å; G269-E287 PolarHBondContact O-N 3.25Å; I285-E287 HydrophobicContact CG2-CG 4.02Å; E287-Y292 HydrophobicContact CB-CE2 4.31Å; E287-Y292 VanDerWaalsContact O-CE2 3.27Å; E287-Y292 WeakPolarHBondContact O-CE2 3.13Å; E287-Y292 WeakPolarHBondContact OE2-CE2 3.41Å; E287-Y292 PolarHBondContact OE2-OH 2.83Å; E287-Y339 HydrophobicContact CG-CE2 3.85Å; E287-Y339 PolarHBondContact OE1-OH 3.09Å; E287-T341 HydrophobicContact CG-CG2 4.28Å; E287-K346 WeakPolarHBondContact OE1-CD 3.16Å; E287-K346 IonicContact OE1-NZ 3.88Å; E287-K346 PolarHBondContact OE1-NZ 2.79Å; E287-K346 IonicContact OE2-NZ 3.32Å; E287-K346 PolarHBondContact OE2-NZ 3.2Å
288G93.7Very high93.3Very high9 Ų952.7 Ų52.79%0.09326%0.256CS..  trans-68.6151.6175.700000112.2G269 D286 K290 N291 Y292G269-G288 PolarHBondContact O-N 3.42Å; D286-G288 WeakPolarHBondContact OD1-CA 3.12Å; D286-G288 PolarHBondContact OD1-N 2.97Å; G288-K290 PolarHBondContact O-N 2.92Å; G288-K290 VanDerWaalsContact O-N 3.13Å; G288-N291 WeakPolarHBondContact O-CB 3.34Å; G288-N291 PolarHBondContact O-N 3.45Å; G288-Y292 WeakPolarHBondContact O-CD2 3.49Å; G288-Y292 PolarHBondContact O-N 3.12Å
289L93.3Very high92.7Very high44 Ų4451.3 Ų51.323%0.2325%0.248CC..Hα-helixtrans-54.9-36.8-177.1-178.161.9000113.3N291 Y292 V293 V310 E313 K314 M342L289-N291 VanDerWaalsContact C-N 3.34Å; L289-N291 PolarHBondContact O-N 3.16Å; L289-Y292 WeakPolarHBondContact O-CB 3.28Å; L289-Y292 PolarHBondContact O-N 3.28Å; L289-V293 HydrophobicContact CD1-CG2 4.45Å; L289-V293 HydrophobicContact CG-CG2 4.49Å; L289-V293 WeakPolarHBondContact O-CG2 3.46Å; L289-V293 PolarHBondContact O-N 2.85Å; L289-V310 HydrophobicContact CD1-CB 4.43Å; L289-V310 HydrophobicContact CD1-CG1 4.18Å; L289-V310 HydrophobicContact CD1-CG2 4.11Å; L289-E313 HydrophobicContact CD1-CB 4.31Å; L289-E313 HydrophobicContact CD1-CG 4.35Å; L289-K314 HydrophobicContact CD2-CD 4.27Å; L289-K314 HydrophobicContact CD2-CG 3.52Å; L289-M342 HydrophobicContact CD1-SD 3.56Å; L289-M342 VanDerWaalsContact CD1-SD 3.56Å
290K92.8Very high92.2Very high154 Ų15456.5 Ų56.567%0.6728%0.275SS*.Hα-helixtrans-58.3-47.1178.3-178.6-179170.7-174.80111.3G288 Y292 V293 E294G288-K290 PolarHBondContact O-N 2.92Å; G288-K290 VanDerWaalsContact O-N 3.13Å; K290-Y292 VanDerWaalsContact C-N 3.29Å; K290-Y292 PolarHBondContact O-N 3.24Å; K290-V293 PolarHBondContact O-N 2.94Å; K290-E294 WeakPolarHBondContact CE-OE1 3.49Å; K290-E294 IonicContact NZ-OE1 2.59Å; K290-E294 WeakPolarHBondContact O-CG 3.35Å; K290-E294 PolarHBondContact O-N 3.06Å
291N93Very high91.7Very high15 Ų1553.2 Ų53.28%0.0826%0.262CS..Hα-helixtrans-60.5-41.4179.1-176.434.1000111.2L17 D286 G288 L289 V293 E294 S295L17-N291 VanDerWaalsContact CD1-OD1 3.25Å; L17-N291 WeakPolarHBondContact CD1-OD1 3.44Å; D286-N291 PolarHBondContact O-ND2 3.4Å; G288-N291 WeakPolarHBondContact O-CB 3.34Å; G288-N291 PolarHBondContact O-N 3.45Å; L289-N291 VanDerWaalsContact C-N 3.34Å; L289-N291 PolarHBondContact O-N 3.16Å; N291-V293 PolarHBondContact O-N 2.84Å; N291-E294 PolarHBondContact O-N 2.73Å; N291-S295 WeakPolarHBondContact O-CB 3.34Å; N291-S295 PolarHBondContact O-N 3.08Å; N291-S295 PolarHBondContact O-OG 2.94Å
292Y93.2Very high91.2Very high0 Ų053.6 Ų53.60%027%0.274CS..Hα-helixtrans-62.6-41.6176.3-80.3-66.1000114E287 G288 L289 K290 S295 K296 Y299 F306 T341 M342 I343 K346E287-Y292 HydrophobicContact CB-CE2 4.31Å; E287-Y292 VanDerWaalsContact O-CE2 3.27Å; E287-Y292 WeakPolarHBondContact O-CE2 3.13Å; E287-Y292 WeakPolarHBondContact OE2-CE2 3.41Å; E287-Y292 PolarHBondContact OE2-OH 2.83Å; G288-Y292 WeakPolarHBondContact O-CD2 3.49Å; G288-Y292 PolarHBondContact O-N 3.12Å; L289-Y292 WeakPolarHBondContact O-CB 3.28Å; L289-Y292 PolarHBondContact O-N 3.28Å; K290-Y292 VanDerWaalsContact C-N 3.29Å; K290-Y292 PolarHBondContact O-N 3.24Å; Y292-S295 CarbonylContact O-C 3.59Å; Y292-S295 PolarHBondContact O-N 2.83Å; Y292-K296 WeakPolarHBondContact O-CA 3.29Å; Y292-K296 PolarHBondContact O-N 2.88Å; Y292-Y299 HydrophobicContact CD1-CD2 4.36Å; Y292-Y299 AromaticContact CD1-CE2 3.53Å; Y292-Y299 HydrophobicContact CD1-CE2 3.53Å; Y292-Y299 AromaticContact CD1-CZ 3.63Å; Y292-Y299 HydrophobicContact CE1-CE1 4.11Å; Y292-Y299 AromaticContact CE1-CE2 3.89Å; Y292-Y299 HydrophobicContact CE1-CE2 3.89Å; Y292-Y299 AromaticContact CE1-CZ 3.48Å; Y292-Y299 VanDerWaalsContact CE1-CZ 3.48Å; Y292-Y299 WeakPolarHBondContact CE1-OH 3.43Å; Y292-F306 WeakPolarHBondContact O-CZ 3.18Å; Y292-T341 WeakPolarHBondContact OH-CB 3.49Å; Y292-T341 WeakPolarHBondContact OH-CG2 3.36Å; Y292-T341 PolarHBondContact OH-OG1 2.88Å; Y292-M342 HydrophobicContact CD1-CE 3.93Å; Y292-M342 HydrophobicContact CD2-CB 4.29Å; Y292-M342 HydrophobicContact CD2-CE 4.21Å; Y292-M342 HydrophobicContact CE2-CB 4.16Å; Y292-M342 HydrophobicContact CG-CE 3.63Å; Y292-I343 HydrophobicContact CD1-CD1 4.04Å; Y292-I343 HydrophobicContact CD1-CG1 3.64Å; Y292-I343 HydrophobicContact CE1-CB 4.31Å; Y292-I343 HydrophobicContact CE1-CD1 4.14Å; Y292-I343 HydrophobicContact CE1-CG1 3.23Å; Y292-K346 WeakPolarHBondContact OH-CE 3.18Å; Y292-K346 PolarHBondContact OH-NZ 2.78Å; Y292-K346 VanDerWaalsContact OH-NZ 3.12Å
293V92.2Very high90.9Very high81 Ų8155.8 Ų55.849%0.49128%0.284SS..Hα-helixtrans-65.8-41.6178.7173.10000110.7L289 K290 N291 S295L289-V293 HydrophobicContact CD1-CG2 4.45Å; L289-V293 HydrophobicContact CG-CG2 4.49Å; L289-V293 WeakPolarHBondContact O-CG2 3.46Å; L289-V293 PolarHBondContact O-N 2.85Å; K290-V293 PolarHBondContact O-N 2.94Å; N291-V293 PolarHBondContact O-N 2.84Å; V293-S295 VanDerWaalsContact C-N 3.35Å
294E91.1Very high90.6Very high138 Ų13861.2 Ų61.265%0.64531%0.313SS*.Hα-helixtrans-70.2-30.5178.1-70.2174177.600112.8K290 N291K290-E294 WeakPolarHBondContact CE-OE1 3.49Å; K290-E294 IonicContact NZ-OE1 2.59Å; K290-E294 WeakPolarHBondContact O-CG 3.35Å; K290-E294 PolarHBondContact O-N 3.06Å; N291-E294 PolarHBondContact O-N 2.73Å
295S88Confident90.3Very high9 Ų963.1 Ų63.16%0.06332%0.323CS..THydrogen-bonded Turntrans-105.719.5-178.1640000114.2N291 Y292 V293 E297 R298 Y299N291-S295 WeakPolarHBondContact O-CB 3.34Å; N291-S295 PolarHBondContact O-N 3.08Å; N291-S295 PolarHBondContact O-OG 2.94Å; Y292-S295 CarbonylContact O-C 3.59Å; Y292-S295 PolarHBondContact O-N 2.83Å; V293-S295 VanDerWaalsContact C-N 3.35Å; S295-E297 PolarHBondContact O-N 2.8Å; S295-E297 VanDerWaalsContact O-N 3.1Å; S295-R298 WeakPolarHBondContact O-CB 3.46Å; S295-R298 PolarHBondContact O-N 2.85Å; S295-Y299 WeakPolarHBondContact O-CD2 3.2Å
296K86Confident90.2Very high62 Ų6263.6 Ų63.627%0.2732%0.324SS..G310 helixtrans-49-42.6-174.9177.8-175.9172.9-170.30113.6Y292 R298 Y299 N303 F306Y292-K296 WeakPolarHBondContact O-CA 3.29Å; Y292-K296 PolarHBondContact O-N 2.88Å; K296-R298 PolarHBondContact O-N 3.45Å; K296-Y299 PolarHBondContact O-N 2.9Å; K296-Y299 VanDerWaalsContact O-N 3.13Å; K296-N303 WeakPolarHBondContact CE-OD1 3.42Å; K296-N303 PolarHBondContact NZ-OD1 2.82Å; K296-F306 HydrophobicContact CB-CE1 4.27Å; K296-F306 HydrophobicContact CB-CE2 4.16Å; K296-F306 HydrophobicContact CB-CZ 3.91Å; K296-F306 HydrophobicContact CD-CD1 3.78Å; K296-F306 HydrophobicContact CD-CE1 3.85Å; K296-F306 HydrophobicContact CD-CG 4.15Å; K296-F306 HydrophobicContact CD-CZ 4.28Å; K296-F306 HydrophobicContact CG-CD1 4.01Å; K296-F306 HydrophobicContact CG-CD2 3.94Å; K296-F306 HydrophobicContact CG-CE1 3.92Å; K296-F306 HydrophobicContact CG-CE2 3.85Å; K296-F306 HydrophobicContact CG-CG 4.02Å; K296-F306 HydrophobicContact CG-CZ 3.84Å
297E85.5Confident90.1Very high179 Ų17965.2 Ų65.284%0.83634%0.339SS*.G310 helixtrans-60.1-28.9-176.8-64.4-179.6172.300112.6S295 Y299 N300S295-E297 PolarHBondContact O-N 2.8Å; S295-E297 VanDerWaalsContact O-N 3.1Å; E297-Y299 PolarHBondContact O-N 2.81Å; E297-N300 PolarHBondContact O-N 3.26Å; E297-N300 PolarHBondContact O-OD1 2.9Å
298R84.8Confident90Very high103 Ų10371.4 Ų71.439%0.38936%0.362SS..G310 helixtrans-64-24.2178.8-61.4-172.6-170.3-179.42.2113.3C14 G15 S295 K296C14-R298 PolarHBondContact SG-O 3.08Å; C14-R298 VanDerWaalsContact SG-O 3.39Å; G15-R298 PolarHBondContact O-NH1 3.42Å; S295-R298 WeakPolarHBondContact O-CB 3.46Å; S295-R298 PolarHBondContact O-N 2.85Å; K296-R298 PolarHBondContact O-N 3.45Å
299Y85.3Confident90.1Very high14 Ų1471.3 Ų71.36%0.05536%0.359CS..G310 helixtrans-93.7-7-172.3-57.9-71.9000113.2Y292 S295 K296 E297 L301 I343 I358 K361Y292-Y299 HydrophobicContact CD1-CD2 4.36Å; Y292-Y299 AromaticContact CD1-CE2 3.53Å; Y292-Y299 HydrophobicContact CD1-CE2 3.53Å; Y292-Y299 AromaticContact CD1-CZ 3.63Å; Y292-Y299 HydrophobicContact CE1-CE1 4.11Å; Y292-Y299 AromaticContact CE1-CE2 3.89Å; Y292-Y299 HydrophobicContact CE1-CE2 3.89Å; Y292-Y299 AromaticContact CE1-CZ 3.48Å; Y292-Y299 VanDerWaalsContact CE1-CZ 3.48Å; Y292-Y299 WeakPolarHBondContact CE1-OH 3.43Å; S295-Y299 WeakPolarHBondContact O-CD2 3.2Å; K296-Y299 PolarHBondContact O-N 2.9Å; K296-Y299 VanDerWaalsContact O-N 3.13Å; E297-Y299 PolarHBondContact O-N 2.81Å; Y299-L301 PolarHBondContact O-N 3.17Å; Y299-I343 HydrophobicContact CD1-CB 4.48Å; Y299-I343 HydrophobicContact CD1-CD1 4.3Å; Y299-I343 HydrophobicContact CD1-CG1 3.95Å; Y299-I343 HydrophobicContact CD1-CG2 3.97Å; Y299-I343 HydrophobicContact CD2-CD1 4.15Å; Y299-I343 HydrophobicContact CD2-CG1 4.4Å; Y299-I343 HydrophobicContact CE1-CG1 4Å; Y299-I343 HydrophobicContact CE2-CG1 4.47Å; Y299-I343 HydrophobicContact CG-CD1 3.99Å; Y299-I343 HydrophobicContact CG-CG1 4.14Å; Y299-I358 HydrophobicContact CD1-CD1 4.46Å; Y299-I358 HydrophobicContact CE1-CD1 4.47Å; Y299-K361 WeakPolarHBondContact O-CE 3.28Å; Y299-K361 PolarHBondContact O-NZ 2.86Å
300N85.8Confident90.2Very high108 Ų10870.2 Ų70.258%0.57835%0.354SS*.  trans4838178.7-69.8-29.1000113.4E12 E297E12-N300 PolarHBondContact OE1-ND2 2.8Å; E12-N300 PolarHBondContact OE2-ND2 3.32Å; E297-N300 PolarHBondContact O-N 3.26Å; E297-N300 PolarHBondContact O-OD1 2.9Å
301L86.9Confident90.4Very high29 Ų2965.6 Ų65.615%0.15235%0.345CS..  trans-97.1142.9178.5-76.2170.2000110.9Y299 F306 K309 I343 K361Y299-L301 PolarHBondContact O-N 3.17Å; L301-F306 HydrophobicContact CB-CB 4.38Å; L301-F306 HydrophobicContact CD1-CD2 4.3Å; L301-K309 HydrophobicContact CD1-CD 4.12Å; L301-I343 HydrophobicContact CD1-CD1 3.69Å; L301-I343 HydrophobicContact CD1-CG2 4.33Å; L301-K361 HydrophobicContact CD2-CG 4.31Å
302G88Confident90.5Very high41 Ų4167 Ų6742%0.42335%0.352SS..  trans-58.8145172.500000111.8L304 D305 F306G302-L304 VanDerWaalsContact C-N 3.27Å; G302-L304 PolarHBondContact O-N 3.04Å; G302-D305 PolarHBondContact O-N 2.8Å; G302-F306 PolarHBondContact O-N 3.07Å
303N88.7Confident90.6Very high113 Ų11367.2 Ų67.260%0.60435%0.353SS*.Hα-helixtrans-54.4-42.8-176.6-74.7-22.7000112.8K296 S307K296-N303 WeakPolarHBondContact CE-OD1 3.42Å; K296-N303 PolarHBondContact NZ-OD1 2.82Å; N303-S307 WeakPolarHBondContact O-CB 3.47Å; N303-S307 PolarHBondContact O-N 3.01Å; N303-S307 PolarHBondContact O-OG 3.15Å; N303-S307 VanDerWaalsContact O-OG 3.09Å
304L90Very high90.8Very high130 Ų13069 Ų6968%0.68135%0.354SS*.Hα-helixtrans-64.6-46.1-179.7-70171.3000112G302 S307 R308G302-L304 VanDerWaalsContact C-N 3.27Å; G302-L304 PolarHBondContact O-N 3.04Å; L304-S307 PolarHBondContact O-N 2.81Å; L304-R308 WeakPolarHBondContact O-CG 3.32Å; L304-R308 PolarHBondContact O-N 2.95Å
305D91.1Very high91Very high54 Ų5466.2 Ų66.229%0.28934%0.341SS..Hα-helixtrans-69.1-39.6-179.2-61.7-37.1000111.5G302 R308 K309G302-D305 PolarHBondContact O-N 2.8Å; D305-R308 PolarHBondContact O-N 2.97Å; D305-R308 IonicContact OD1-NH1 3.61Å; D305-R308 PolarHBondContact OD1-NH1 3.27Å; D305-K309 WeakPolarHBondContact O-CG 3.3Å; D305-K309 PolarHBondContact O-N 3.32Å
306F93.4Very high91.3Very high9 Ų965.8 Ų65.84%0.03934%0.338CS..Hα-helixtrans-61.4-46.4173.2-172.2-92.2000111.5Y292 K296 L301 G302 R308 K309 V310 M342 I343Y292-F306 WeakPolarHBondContact O-CZ 3.18Å; K296-F306 HydrophobicContact CB-CE1 4.27Å; K296-F306 HydrophobicContact CB-CE2 4.16Å; K296-F306 HydrophobicContact CB-CZ 3.91Å; K296-F306 HydrophobicContact CD-CD1 3.78Å; K296-F306 HydrophobicContact CD-CE1 3.85Å; K296-F306 HydrophobicContact CD-CG 4.15Å; K296-F306 HydrophobicContact CD-CZ 4.28Å; K296-F306 HydrophobicContact CG-CD1 4.01Å; K296-F306 HydrophobicContact CG-CD2 3.94Å; K296-F306 HydrophobicContact CG-CE1 3.92Å; K296-F306 HydrophobicContact CG-CE2 3.85Å; K296-F306 HydrophobicContact CG-CG 4.02Å; K296-F306 HydrophobicContact CG-CZ 3.84Å; L301-F306 HydrophobicContact CB-CB 4.38Å; L301-F306 HydrophobicContact CD1-CD2 4.3Å; G302-F306 PolarHBondContact O-N 3.07Å; F306-R308 VanDerWaalsContact C-N 3.32Å; F306-R308 PolarHBondContact O-N 3.24Å; F306-K309 PolarHBondContact O-N 3.46Å; F306-V310 HydrophobicContact CD1-CG2 3.86Å; F306-V310 HydrophobicContact CE1-CG2 3.5Å; F306-V310 HydrophobicContact CZ-CG2 3.99Å; F306-V310 WeakPolarHBondContact O-CG2 3.46Å; F306-V310 PolarHBondContact O-N 3.12Å; F306-M342 HydrophobicContact CD2-CE 4.41Å; F306-M342 HydrophobicContact CE2-CE 3.72Å; F306-M342 HydrophobicContact CZ-CE 3.96Å; F306-I343 HydrophobicContact CD2-CD1 4.43Å; F306-I343 HydrophobicContact CE2-CD1 4.23Å
307S93.4Very high91.6Very high72 Ų7265.6 Ų65.650%0.50334%0.336SS..Hα-helixtrans-61.3-38.5176.9-72.30000112.8N303 L304 V310 A311N303-S307 WeakPolarHBondContact O-CB 3.47Å; N303-S307 PolarHBondContact O-N 3.01Å; N303-S307 PolarHBondContact O-OG 3.15Å; N303-S307 VanDerWaalsContact O-OG 3.09Å; L304-S307 PolarHBondContact O-N 2.81Å; S307-V310 PolarHBondContact O-N 3.25Å; S307-A311 PolarHBondContact O-N 2.88Å
308R93.9Very high91.9Very high135 Ų13564.8 Ų64.851%0.50933%0.332SS..Hα-helixtrans-62.9-48.2173.2-74.3171179.2163.8-4.8111.6L304 D305 F306 V310 A311 I312L304-R308 WeakPolarHBondContact O-CG 3.32Å; L304-R308 PolarHBondContact O-N 2.95Å; D305-R308 PolarHBondContact O-N 2.97Å; D305-R308 IonicContact OD1-NH1 3.61Å; D305-R308 PolarHBondContact OD1-NH1 3.27Å; F306-R308 VanDerWaalsContact C-N 3.32Å; F306-R308 PolarHBondContact O-N 3.24Å; R308-V310 VanDerWaalsContact C-N 3.33Å; R308-V310 PolarHBondContact O-N 3.21Å; R308-A311 WeakPolarHBondContact O-CB 3.48Å; R308-A311 PolarHBondContact O-N 3.09Å; R308-A311 VanDerWaalsContact O-N 3.15Å; R308-I312 WeakPolarHBondContact O-CG1 3.33Å; R308-I312 PolarHBondContact O-N 3.45Å
309K95.8Very high92.2Very high8 Ų862 Ų624%0.03533%0.325CS..Hα-helixtrans-59-42.9177.1-75.6174178-820111.8L301 D305 F306 A311 I312 E313 M342 I343 K361 E363L301-K309 HydrophobicContact CD1-CD 4.12Å; D305-K309 WeakPolarHBondContact O-CG 3.3Å; D305-K309 PolarHBondContact O-N 3.32Å; F306-K309 PolarHBondContact O-N 3.46Å; K309-A311 PolarHBondContact O-N 3.48Å; K309-I312 PolarHBondContact O-N 3.47Å; K309-E313 WeakPolarHBondContact O-CB 3.5Å; K309-E313 PolarHBondContact O-N 3.15Å; K309-M342 HydrophobicContact CB-CG 3.96Å; K309-M342 HydrophobicContact CB-SD 4.47Å; K309-I343 PolarHBondContact NZ-O 3.44Å; K309-K361 WeakPolarHBondContact CE-O 3.34Å; K309-K361 PolarHBondContact NZ-O 3.28Å; K309-E363 WeakPolarHBondContact CE-O 3.46Å; K309-E363 PolarHBondContact NZ-O 2.99Å
310V95.6Very high92.1Very high20 Ų2065.2 Ų65.212%0.12135%0.346CS..Hα-helixtrans-61.4-41.3174.8166.90000112.1L289 F306 S307 R308 E313 K314 M342L289-V310 HydrophobicContact CD1-CB 4.43Å; L289-V310 HydrophobicContact CD1-CG1 4.18Å; L289-V310 HydrophobicContact CD1-CG2 4.11Å; F306-V310 HydrophobicContact CD1-CG2 3.86Å; F306-V310 HydrophobicContact CE1-CG2 3.5Å; F306-V310 HydrophobicContact CZ-CG2 3.99Å; F306-V310 WeakPolarHBondContact O-CG2 3.46Å; F306-V310 PolarHBondContact O-N 3.12Å; S307-V310 PolarHBondContact O-N 3.25Å; R308-V310 VanDerWaalsContact C-N 3.33Å; R308-V310 PolarHBondContact O-N 3.21Å; V310-E313 PolarHBondContact O-N 3.35Å; V310-K314 HydrophobicContact CG1-CD 4.47Å; V310-K314 WeakPolarHBondContact O-CG 3.42Å; V310-K314 PolarHBondContact O-N 3.07Å; V310-K314 VanDerWaalsContact O-N 3.09Å; V310-M342 HydrophobicContact CB-SD 4.48Å; V310-M342 HydrophobicContact CG2-CE 4.13Å; V310-M342 HydrophobicContact CG2-SD 3.86Å
311A95.7Very high92.1Very high58 Ų5865.6 Ų65.648%0.47935%0.348SS..Hα-helixtrans-64.2-46.217800000111.5S307 R308 K309 E313 K314 E315S307-A311 PolarHBondContact O-N 2.88Å; R308-A311 WeakPolarHBondContact O-CB 3.48Å; R308-A311 PolarHBondContact O-N 3.09Å; R308-A311 VanDerWaalsContact O-N 3.15Å; K309-A311 PolarHBondContact O-N 3.48Å; A311-E313 VanDerWaalsContact C-N 3.34Å; A311-E313 PolarHBondContact O-N 3.47Å; A311-K314 PolarHBondContact O-N 3.23Å; A311-E315 PolarHBondContact O-N 3Å; A311-E315 VanDerWaalsContact O-N 3.12Å
312I95.5Very high92.3Very high45 Ų4565.3 Ų65.323%0.23135%0.349CS..Hα-helixtrans-61.8-41.9176.7-64.4167.1000111R308 K309 K314 E315 L316 R366 Y419R308-I312 WeakPolarHBondContact O-CG1 3.33Å; R308-I312 PolarHBondContact O-N 3.45Å; K309-I312 PolarHBondContact O-N 3.47Å; I312-K314 PolarHBondContact O-N 3.2Å; I312-E315 PolarHBondContact O-N 3.28Å; I312-L316 WeakPolarHBondContact O-CB 3.29Å; I312-L316 PolarHBondContact O-N 2.89Å; I312-R366 HydrophobicContact CG2-CB 3.68Å; I312-R366 HydrophobicContact CG2-CG 4.37Å; I312-Y419 HydrophobicContact CG2-CD1 3.98Å
313E95.9Very high92.5Very high3 Ų363.5 Ų63.51%0.01433%0.329CS..Hα-helixtrans-63.8-42.2179.4-161.971.6169.400111.7L289 K309 V310 A311 E315 L316 Y317 M342 R366L289-E313 HydrophobicContact CD1-CB 4.31Å; L289-E313 HydrophobicContact CD1-CG 4.35Å; K309-E313 WeakPolarHBondContact O-CB 3.5Å; K309-E313 PolarHBondContact O-N 3.15Å; V310-E313 PolarHBondContact O-N 3.35Å; A311-E313 VanDerWaalsContact C-N 3.34Å; A311-E313 PolarHBondContact O-N 3.47Å; E313-E315 VanDerWaalsContact C-N 3.32Å; E313-E315 PolarHBondContact O-N 3.07Å; E313-L316 PolarHBondContact O-N 2.71Å; E313-Y317 HydrophobicContact CG-CD2 4.07Å; E313-Y317 HydrophobicContact CG-CE2 3.94Å; E313-Y317 VanDerWaalsContact O-CD2 3.29Å; E313-Y317 WeakPolarHBondContact O-CD2 3.4Å; E313-Y317 PolarHBondContact O-N 2.92Å; E313-Y317 VanDerWaalsContact OE1-CE2 3.28Å; E313-Y317 WeakPolarHBondContact OE1-CE2 3.44Å; E313-M342 HydrophobicContact CB-CB 4.43Å; E313-M342 HydrophobicContact CB-CG 3.93Å; E313-M342 HydrophobicContact CB-SD 3.98Å; E313-M342 HydrophobicContact CG-CB 4.1Å; E313-M342 HydrophobicContact CG-CG 4.15Å; E313-M342 HydrophobicContact CG-SD 4.27Å; E313-R366 IonicContact OE1-CZ 3.09Å; E313-R366 IonicContact OE1-NE 3.95Å; E313-R366 PolarHBondContact OE1-NE 2.68Å; E313-R366 IonicContact OE1-NH2 3.94Å; E313-R366 PolarHBondContact OE1-NH2 3.4Å; E313-R366 WeakPolarHBondContact OE2-CD 3.44Å; E313-R366 IonicContact OE2-CZ 3.45Å; E313-R366 IonicContact OE2-NE 2.7Å; E313-R366 PolarHBondContact OE2-NE 3.13Å; E313-R366 IonicContact OE2-NH2 3.86Å
314K95.4Very high92.6Very high119 Ų11962.5 Ų62.552%0.51732%0.321SS..Hα-helixtrans-60.7-43175.5-74178.9179.5-177.50111.8L289 V310 A311 I312 Q318L289-K314 HydrophobicContact CD2-CD 4.27Å; L289-K314 HydrophobicContact CD2-CG 3.52Å; V310-K314 HydrophobicContact CG1-CD 4.47Å; V310-K314 WeakPolarHBondContact O-CG 3.42Å; V310-K314 PolarHBondContact O-N 3.07Å; V310-K314 VanDerWaalsContact O-N 3.09Å; A311-K314 PolarHBondContact O-N 3.23Å; I312-K314 PolarHBondContact O-N 3.2Å; K314-Q318 WeakPolarHBondContact O-CG 3.46Å; K314-Q318 PolarHBondContact O-N 2.91Å
315E95.4Very high92.9Very high79 Ų7957.3 Ų57.337%0.36929%0.293SS..Hα-helixtrans-65.3-43.6178.2-166.3-170.7176.800111.9A311 I312 E313 Y317 Q318 N319 Y419 K420A311-E315 PolarHBondContact O-N 3Å; A311-E315 VanDerWaalsContact O-N 3.12Å; I312-E315 PolarHBondContact O-N 3.28Å; E313-E315 VanDerWaalsContact C-N 3.32Å; E313-E315 PolarHBondContact O-N 3.07Å; E315-Y317 PolarHBondContact O-N 3.36Å; E315-Q318 WeakPolarHBondContact O-CB 3.32Å; E315-Q318 PolarHBondContact O-N 3.09Å; E315-N319 PolarHBondContact O-N 2.84Å; E315-Y419 HydrophobicContact CB-CE1 4.49Å; E315-Y419 HydrophobicContact CG-CE1 4.3Å; E315-K420 IonicContact OE1-NZ 2.77Å; E315-K420 PolarHBondContact OE1-NZ 2.94Å
316L94.9Very high93.1Very high0 Ų054.8 Ų54.80%028%0.279CS..Hα-helixtrans-58.5-47176.817265.2000111.6I312 E313 Q318 N319 L323 R366 L368 Y419I312-L316 WeakPolarHBondContact O-CB 3.29Å; I312-L316 PolarHBondContact O-N 2.89Å; E313-L316 PolarHBondContact O-N 2.71Å; L316-Q318 PolarHBondContact O-N 3.25Å; L316-N319 CarbonylContact O-C 3.49Å; L316-N319 WeakPolarHBondContact O-CA 3.46Å; L316-N319 PolarHBondContact O-N 3.16Å; L316-L323 HydrophobicContact CD1-CB 4.32Å; L316-L323 HydrophobicContact CD1-CD1 4.36Å; L316-L323 HydrophobicContact CD2-CD1 4.11Å; L316-L323 HydrophobicContact CG-CD1 3.97Å; L316-R366 HydrophobicContact CD2-CG 3.78Å; L316-L368 HydrophobicContact CD1-CD1 4.25Å; L316-L368 HydrophobicContact CD1-CD2 3.89Å; L316-L368 HydrophobicContact CD2-CD2 3.66Å; L316-L368 HydrophobicContact CG-CD2 4.43Å; L316-Y419 HydrophobicContact CB-CE1 4.48Å; L316-Y419 HydrophobicContact CB-CE2 4.46Å; L316-Y419 HydrophobicContact CD1-CD2 3.5Å; L316-Y419 HydrophobicContact CD1-CE2 3.77Å; L316-Y419 HydrophobicContact CD1-CG 4.06Å
317Y93.5Very high93.3Very high59 Ų5956.6 Ų56.623%0.23129%0.287CS..Hα-helixtrans-71.4-16.3-178.9-84.1-106.9000113.6N267 G269 E313 E315 L323N267-Y317 WeakPolarHBondContact O-CD1 3.48Å; N267-Y317 WeakPolarHBondContact O-CE1 3.34Å; G269-Y317 WeakPolarHBondContact CA-OH 3.34Å; E313-Y317 HydrophobicContact CG-CD2 4.07Å; E313-Y317 HydrophobicContact CG-CE2 3.94Å; E313-Y317 VanDerWaalsContact O-CD2 3.29Å; E313-Y317 WeakPolarHBondContact O-CD2 3.4Å; E313-Y317 PolarHBondContact O-N 2.92Å; E313-Y317 VanDerWaalsContact OE1-CE2 3.28Å; E313-Y317 WeakPolarHBondContact OE1-CE2 3.44Å; E315-Y317 PolarHBondContact O-N 3.36Å; Y317-L323 HydrophobicContact CD1-CD2 4.02Å; Y317-L323 HydrophobicContact CD2-CD1 4.3Å; Y317-L323 HydrophobicContact CE1-CD2 4.3Å; Y317-L323 HydrophobicContact CE2-CD1 4.12Å; Y317-L323 HydrophobicContact CG-CD2 4.33Å
318Q91.7Very high93.5Very high161 Ų16153.4 Ų53.475%0.75227%0.265SS*.Hα-helixtrans-79.8-21.4168-70.5171.6-3.500112.2K314 E315 L316K314-Q318 WeakPolarHBondContact O-CG 3.46Å; K314-Q318 PolarHBondContact O-N 2.91Å; E315-Q318 WeakPolarHBondContact O-CB 3.32Å; E315-Q318 PolarHBondContact O-N 3.09Å; L316-Q318 PolarHBondContact O-N 3.25Å
319N89.6Confident93.7Very high44 Ų4448.5 Ų48.524%0.23525%0.25CC..  trans-10679.7-179.5-171.4-24.2000111.2E315 L316 N321 S322 L323E315-N319 PolarHBondContact O-N 2.84Å; L316-N319 CarbonylContact O-C 3.49Å; L316-N319 WeakPolarHBondContact O-CA 3.46Å; L316-N319 PolarHBondContact O-N 3.16Å; N319-N321 PolarHBondContact O-N 3.32Å; N319-N321 VanDerWaalsContact O-N 3.13Å; N319-N321 PolarHBondContact OD1-N 3.26Å; N319-S322 PolarHBondContact ND2-OG 2.91Å; N319-S322 PolarHBondContact O-N 3.43Å; N319-S322 PolarHBondContact OD1-N 3.45Å; N319-S322 PolarHBondContact OD1-OG 3.36Å; N319-L323 PolarHBondContact O-N 3.06Å
320T84Confident93.8Very high83 Ų8349 Ų4951%0.50925%0.252SS..Hα-helixtrans-54.3-34179.7-44.80000112.9S322 L323 Q324T320-S322 PolarHBondContact O-N 3.26Å; T320-L323 PolarHBondContact O-N 2.71Å; T320-Q324 PolarHBondContact O-N 3.16Å; T320-Q324 VanDerWaalsContact O-N 3.12Å
321N85.8Confident93.8Very high115 Ų11548.3 Ų48.362%0.61525%0.247SC*.Hα-helixtrans-64-27.4179.2-68.3-19.8000113.3N319 Q324 F325N319-N321 PolarHBondContact O-N 3.32Å; N319-N321 VanDerWaalsContact O-N 3.13Å; N319-N321 PolarHBondContact OD1-N 3.26Å; N321-Q324 WeakPolarHBondContact O-CG 3.22Å; N321-Q324 PolarHBondContact O-NE2 3.28Å; N321-F325 WeakPolarHBondContact O-CE2 3.37Å
322S90.5Very high93.6Very high23 Ų2350 Ų5016%0.16125%0.248CC..Hα-helixtrans-91.1-35.9173.8-57.70000111.7N319 T320 Q324 F325N319-S322 PolarHBondContact ND2-OG 2.91Å; N319-S322 PolarHBondContact O-N 3.43Å; N319-S322 PolarHBondContact OD1-N 3.45Å; N319-S322 PolarHBondContact OD1-OG 3.36Å; T320-S322 PolarHBondContact O-N 3.26Å; S322-Q324 VanDerWaalsContact C-N 3.26Å; S322-Q324 PolarHBondContact O-N 3.36Å; S322-F325 WeakPolarHBondContact O-CD2 3.48Å; S322-F325 PolarHBondContact O-N 3.44Å; S322-F325 VanDerWaalsContact O-N 3.16Å
323L92.1Very high93.5Very high3 Ų351.1 Ų51.12%0.01626%0.257CS..Hα-helixtrans-61.4-34-178.1-175.364.6000112.5L251 N267 L316 Y317 N319 T320 F325 T326L251-L323 HydrophobicContact CD1-CD1 4.1Å; L251-L323 HydrophobicContact CD1-CD2 3.77Å; L251-L323 HydrophobicContact CD1-CG 3.6Å; L251-L323 HydrophobicContact CD2-CD2 4.38Å; L251-L323 HydrophobicContact CD2-CG 4.24Å; N267-L323 HydrophobicContact CB-CD2 4.18Å; L316-L323 HydrophobicContact CD1-CB 4.32Å; L316-L323 HydrophobicContact CD1-CD1 4.36Å; L316-L323 HydrophobicContact CD2-CD1 4.11Å; L316-L323 HydrophobicContact CG-CD1 3.97Å; Y317-L323 HydrophobicContact CD1-CD2 4.02Å; Y317-L323 HydrophobicContact CD2-CD1 4.3Å; Y317-L323 HydrophobicContact CE1-CD2 4.3Å; Y317-L323 HydrophobicContact CE2-CD1 4.12Å; Y317-L323 HydrophobicContact CG-CD2 4.33Å; N319-L323 PolarHBondContact O-N 3.06Å; T320-L323 PolarHBondContact O-N 2.71Å; L323-F325 PolarHBondContact O-N 2.84Å; L323-F325 VanDerWaalsContact O-N 3.16Å; L323-T326 WeakPolarHBondContact O-CB 3.32Å; L323-T326 PolarHBondContact O-N 2.8Å; L323-T326 VanDerWaalsContact O-N 3.08Å; L323-T326 PolarHBondContact O-OG1 3.24Å
324Q92.1Very high93.5Very high92 Ų9251.2 Ų51.243%0.4326%0.259SS..THydrogen-bonded Turntrans-60.1-20.3176.770.4-175.8-29.200114.5T320 N321 S322 T326T320-Q324 PolarHBondContact O-N 3.16Å; T320-Q324 VanDerWaalsContact O-N 3.12Å; N321-Q324 WeakPolarHBondContact O-CG 3.22Å; N321-Q324 PolarHBondContact O-NE2 3.28Å; S322-Q324 VanDerWaalsContact C-N 3.26Å; S322-Q324 PolarHBondContact O-N 3.36Å; Q324-T326 PolarHBondContact O-N 3.09Å
325F94.6Very high93.5Very high21 Ų2147.2 Ų47.29%0.09224%0.243CC..THydrogen-bonded Turntrans-78.1-3.4177.2-59.7-50.5000113.1H60 N321 S322 L323 K327 L368 C369H60-F325 AromaticContact CE1-CD1 3.85Å; H60-F325 AromaticContact CE1-CE1 3.52Å; N321-F325 WeakPolarHBondContact O-CE2 3.37Å; S322-F325 WeakPolarHBondContact O-CD2 3.48Å; S322-F325 PolarHBondContact O-N 3.44Å; S322-F325 VanDerWaalsContact O-N 3.16Å; L323-F325 PolarHBondContact O-N 2.84Å; L323-F325 VanDerWaalsContact O-N 3.16Å; F325-K327 PolarHBondContact O-N 3.41Å; F325-L368 CarbonylContact O-C 3.5Å; F325-C369 VanDerWaalsContact O-CA 3.23Å; F325-C369 WeakPolarHBondContact O-CA 3.41Å; F325-C369 VanDerWaalsContact O-CB 3.22Å; F325-C369 WeakPolarHBondContact O-CB 3.42Å; F325-C369 PolarHBondContact O-N 3.25Å
326T96.6Very high93.6Very high1 Ų143.5 Ų43.51%0.00623%0.226CC..  trans-63121.1176.8-550000110.3C252 F265 L323 Q324 P340 L368C252-T326 WeakPolarHBondContact CB-O 2.84Å; F265-T326 HydrophobicContact CD1-CG2 3.87Å; F265-T326 HydrophobicContact CE1-CG2 3.71Å; L323-T326 WeakPolarHBondContact O-CB 3.32Å; L323-T326 PolarHBondContact O-N 2.8Å; L323-T326 VanDerWaalsContact O-N 3.08Å; L323-T326 PolarHBondContact O-OG1 3.24Å; Q324-T326 PolarHBondContact O-N 3.09Å; T326-P340 HydrophobicContact CG2-CG 4.14Å; T326-L368 WeakPolarHBondContact CA-O 3.09Å
327K97.2Very high93.8Very high48 Ų4843.5 Ų43.521%0.20923%0.226CC..  trans-116.6141.2175.6-77.5-69.1-165170.60111.1E196 F325 P340 L368 I370E196-K327 IonicContact OE1-NZ 2.99Å; F325-K327 PolarHBondContact O-N 3.41Å; K327-P340 WeakPolarHBondContact O-CD 3.33Å; K327-L368 PolarHBondContact N-O 2.91Å; K327-I370 WeakPolarHBondContact O-CG1 3.49Å
328V97.9Very high94Very high5 Ų540.7 Ų40.73%0.0322%0.215CC..  trans-113.4136.4173.61740000107C252 T254 F265 L271 L337C252-V328 HydrophobicContact CB-CG2 4.43Å; C252-V328 PolarHBondContact SG-N 2.99Å; T254-V328 WeakPolarHBondContact CG2-O 3.41Å; T254-V328 PolarHBondContact OG1-O 2.85Å; F265-V328 HydrophobicContact CB-CG2 3.97Å; F265-V328 HydrophobicContact CG-CG2 4.35Å; L271-V328 HydrophobicContact CD2-CG1 4.37Å; L271-V328 HydrophobicContact CD2-CG2 3.99Å; V328-L337 HydrophobicContact CG1-CD1 3.55Å; V328-L337 HydrophobicContact CG1-CD2 3.89Å; V328-L337 HydrophobicContact CG1-CG 3.74Å
329V97.8Very high94.3Very high31 Ų3133.2 Ų33.219%0.18818%0.18CC..EExtended strand (participates in β ladder)trans-134.8146.2-178-59.20000110.7I338 I370 L372V329-I338 HydrophobicContact CG2-CB 3.96Å; V329-I338 PolarHBondContact N-O 3Å; V329-I338 PolarHBondContact O-N 2.81Å; V329-I370 HydrophobicContact CG1-CG1 4.46Å; V329-I370 HydrophobicContact CG2-CD1 3.86Å; V329-I370 HydrophobicContact CG2-CG1 4.19Å; V329-L372 HydrophobicContact CG2-CB 4.49Å
330Y97.9Very high94.7Very high20 Ų2031.2 Ų31.28%0.07817%0.169CC..EExtended strand (participates in β ladder)trans-86.5156.6164.3-80.4-87.3000109.8T254 R256 E261 V263 F336 L337 V350T254-Y330 HydrophobicContact CG2-CD2 3.69Å; T254-Y330 HydrophobicContact CG2-CE2 4.17Å; R256-Y330 HydrophobicContact CB-CD2 4.21Å; R256-Y330 HydrophobicContact CB-CE1 4.16Å; R256-Y330 HydrophobicContact CB-CE2 3.85Å; R256-Y330 HydrophobicContact CG-CD1 3.99Å; R256-Y330 HydrophobicContact CG-CD2 4.47Å; R256-Y330 HydrophobicContact CG-CE1 3.74Å; R256-Y330 HydrophobicContact CG-CE2 4.3Å; R256-Y330 HydrophobicContact CG-CG 4.33Å; E261-Y330 PolarHBondContact OE1-OH 3.27Å; V263-Y330 HydrophobicContact CG2-CE2 4Å; V263-Y330 WeakPolarHBondContact CG2-OH 3.4Å; Y330-F336 WeakPolarHBondContact CA-O 3.23Å; Y330-F336 WeakPolarHBondContact CD1-O 3.38Å; Y330-L337 HydrophobicContact CD1-CB 4.47Å; Y330-L337 HydrophobicContact CD1-CD1 3.91Å; Y330-L337 HydrophobicContact CD2-CD1 3.64Å; Y330-L337 HydrophobicContact CE1-CB 4.33Å; Y330-L337 HydrophobicContact CE1-CD1 3.82Å; Y330-L337 HydrophobicContact CE2-CD1 3.5Å; Y330-L337 HydrophobicContact CG-CD1 3.84Å; Y330-V350 HydrophobicContact CD1-CG2 4.29Å; Y330-V350 HydrophobicContact CE1-CG2 3.65Å
331D95.7Very high95.3Very high5 Ų527.5 Ų27.53%0.02715%0.146CC..  trans-70165.415980-62.9000111I42 P257 T333 G334 N335 F336 L372I42-D331 HydrophobicContact CD1-CB 4.24Å; P257-D331 WeakPolarHBondContact CG-O 3.27Å; D331-T333 PolarHBondContact O-N 2.82Å; D331-T333 VanDerWaalsContact O-N 3.09Å; D331-T333 VanDerWaalsContact OD2-CB 3.29Å; D331-T333 WeakPolarHBondContact OD2-CB 3.43Å; D331-T333 PolarHBondContact OD2-N 2.87Å; D331-T333 PolarHBondContact OD2-OG1 2.91Å; D331-G334 PolarHBondContact O-N 3.34Å; D331-G334 PolarHBondContact OD1-N 2.8Å; D331-N335 PolarHBondContact OD1-N 3.32Å; D331-F336 HydrophobicContact CB-CB 4.39Å; D331-F336 PolarHBondContact N-O 3.05Å; D331-F336 WeakPolarHBondContact OD1-CA 3.38Å; D331-F336 PolarHBondContact OD1-N 2.86Å; D331-F336 VanDerWaalsContact OD1-O 3.08Å; D331-L372 HydrophobicContact CB-CD2 3.98Å
332D91.4Very high95.7Very high94 Ų9422.2 Ų22.250%0.50312%0.118SC..THydrogen-bonded Turntrans-59-26.2-177.4-79.6-24.1000113.4
333T93.2Very high96Very high68 Ų6821.1 Ų21.142%0.41711%0.11SC..THydrogen-bonded Turntrans-85.4-17.3178.777.30000113.2Y38 D331 N335Y38-T333 HydrophobicContact CD1-CG2 3.73Å; Y38-T333 HydrophobicContact CE1-CG2 3.92Å; D331-T333 PolarHBondContact O-N 2.82Å; D331-T333 VanDerWaalsContact O-N 3.09Å; D331-T333 VanDerWaalsContact OD2-CB 3.29Å; D331-T333 WeakPolarHBondContact OD2-CB 3.43Å; D331-T333 PolarHBondContact OD2-N 2.87Å; D331-T333 PolarHBondContact OD2-OG1 2.91Å; T333-N335 PolarHBondContact O-N 2.92Å; T333-N335 WeakPolarHBondContact OG1-CB 3.23Å; T333-N335 PolarHBondContact OG1-N 2.89Å; T333-N335 PolarHBondContact OG1-ND2 3.45Å
334G95.3Very high96.2Very high5 Ų521 Ų215%0.05211%0.11CC..SBendtrans756.3-17500000114.7R256 D331R256-G334 WeakPolarHBondContact CD-O 3.22Å; D331-G334 PolarHBondContact O-N 3.34Å; D331-G334 PolarHBondContact OD1-N 2.8Å
335N96.1Very high96.4Very high35 Ų3516.6 Ų16.619%0.1879%0.089CC..SBendtrans-78.4-25.1179.3-73.4-45.6000112.7L32 D331 T333 V350L32-N335 HydrophobicContact CD1-CB 4.46Å; L32-N335 WeakPolarHBondContact CD1-OD1 3.07Å; L32-N335 HydrophobicContact CD2-CB 3.69Å; D331-N335 PolarHBondContact OD1-N 3.32Å; T333-N335 PolarHBondContact O-N 2.92Å; T333-N335 WeakPolarHBondContact OG1-CB 3.23Å; T333-N335 PolarHBondContact OG1-N 2.89Å; T333-N335 PolarHBondContact OG1-ND2 3.45Å; N335-V350 WeakPolarHBondContact O-CB 3.5Å; N335-V350 WeakPolarHBondContact O-CG2 3.42Å; N335-V350 PolarHBondContact O-N 3.46Å
336F97.9Very high96.6Very high0 Ų015.8 Ų15.80%09%0.086CC..EExtended strand (participates in β ladder)trans-123.2135.7-178.5-56.7-78.3000111.7L32 E35 L39 I42 Y330 D331 V347 L348 N349 V356L32-F336 HydrophobicContact CD2-CE1 4.49Å; L32-F336 HydrophobicContact CD2-CE2 4.26Å; L32-F336 HydrophobicContact CD2-CZ 3.87Å; E35-F336 HydrophobicContact CG-CE1 4.35Å; E35-F336 HydrophobicContact CG-CZ 3.95Å; L39-F336 HydrophobicContact CD1-CZ 4.5Å; L39-F336 HydrophobicContact CD2-CD1 4.35Å; L39-F336 HydrophobicContact CD2-CE1 3.83Å; L39-F336 HydrophobicContact CD2-CE2 4.24Å; L39-F336 HydrophobicContact CD2-CZ 3.77Å; L39-F336 HydrophobicContact CG-CE1 4.12Å; L39-F336 HydrophobicContact CG-CE2 4.25Å; L39-F336 HydrophobicContact CG-CZ 3.66Å; I42-F336 HydrophobicContact CD1-CB 3.7Å; I42-F336 HydrophobicContact CD1-CD2 3.67Å; I42-F336 HydrophobicContact CD1-CE2 4.46Å; I42-F336 HydrophobicContact CD1-CG 3.74Å; Y330-F336 WeakPolarHBondContact CA-O 3.23Å; Y330-F336 WeakPolarHBondContact CD1-O 3.38Å; D331-F336 HydrophobicContact CB-CB 4.39Å; D331-F336 PolarHBondContact N-O 3.05Å; D331-F336 WeakPolarHBondContact OD1-CA 3.38Å; D331-F336 PolarHBondContact OD1-N 2.86Å; D331-F336 VanDerWaalsContact OD1-O 3.08Å; F336-V347 HydrophobicContact CB-CG1 4Å; F336-V347 HydrophobicContact CD1-CG1 4.03Å; F336-V347 HydrophobicContact CG-CG1 4.2Å; F336-L348 CarbonylContact C-O 3.58Å; F336-L348 WeakPolarHBondContact CA-O 3.48Å; F336-N349 HydrophobicContact CD1-CB 4.05Å; F336-N349 HydrophobicContact CE1-CB 3.85Å; F336-V356 HydrophobicContact CD1-CG2 3.99Å; F336-V356 HydrophobicContact CE1-CG2 3.91Å
337L98.2Very high96.7Very high0 Ų015.8 Ų15.80%09%0.086CC..EExtended strand (participates in β ladder)trans-103.7126.9168.4-167.975.1000108.5V263 L271 F273 V328 Y330 Y339 L348 V350V263-L337 HydrophobicContact CG1-CD2 4.25Å; V263-L337 HydrophobicContact CG2-CD1 4.44Å; V263-L337 HydrophobicContact CG2-CD2 4.35Å; L271-L337 HydrophobicContact CD1-CD2 4.29Å; L271-L337 HydrophobicContact CD2-CD2 4.49Å; F273-L337 HydrophobicContact CE1-CD2 3.94Å; F273-L337 HydrophobicContact CE2-CD2 4.48Å; F273-L337 HydrophobicContact CZ-CD2 3.51Å; V328-L337 HydrophobicContact CG1-CD1 3.55Å; V328-L337 HydrophobicContact CG1-CD2 3.89Å; V328-L337 HydrophobicContact CG1-CG 3.74Å; Y330-L337 HydrophobicContact CD1-CB 4.47Å; Y330-L337 HydrophobicContact CD1-CD1 3.91Å; Y330-L337 HydrophobicContact CD2-CD1 3.64Å; Y330-L337 HydrophobicContact CE1-CB 4.33Å; Y330-L337 HydrophobicContact CE1-CD1 3.82Å; Y330-L337 HydrophobicContact CE2-CD1 3.5Å; Y330-L337 HydrophobicContact CG-CD1 3.84Å; L337-Y339 HydrophobicContact CB-CD1 4.46Å; L337-Y339 HydrophobicContact CD2-CD1 3.98Å; L337-Y339 HydrophobicContact CD2-CE1 4.23Å; L337-Y339 HydrophobicContact CG-CD1 4.01Å; L337-Y339 HydrophobicContact CG-CE1 4.48Å; L337-L348 HydrophobicContact CB-CB 4.37Å; L337-L348 HydrophobicContact CB-CD2 4.42Å; L337-L348 PolarHBondContact N-O 2.84Å; L337-L348 PolarHBondContact O-N 2.85Å; L337-V350 HydrophobicContact CB-CG2 3.99Å
338I98.5Very high96.7Very high0 Ų013.5 Ų13.50%08%0.076CC..EExtended strand (participates in β ladder)trans-111.3127.3-179.3-50169.2000107.4I42 V329 I345 K346 V347 I370 L372 I414I42-I338 HydrophobicContact CD1-CD1 4.21Å; I42-I338 HydrophobicContact CG1-CD1 4.4Å; I42-I338 HydrophobicContact CG2-CD1 4.33Å; V329-I338 HydrophobicContact CG2-CB 3.96Å; V329-I338 PolarHBondContact N-O 3Å; V329-I338 PolarHBondContact O-N 2.81Å; I338-I345 HydrophobicContact CG2-CG2 3.48Å; I338-I345 VanDerWaalsContact CG2-CG2 3.48Å; I338-K346 VanDerWaalsContact CA-O 3.32Å; I338-K346 WeakPolarHBondContact CA-O 3.43Å; I338-V347 HydrophobicContact CG1-CG1 4.41Å; I338-V347 HydrophobicContact CG1-CG2 4.43Å; I338-V347 HydrophobicContact CG2-CG2 4.45Å; I338-I370 HydrophobicContact CB-CD1 4.24Å; I338-I370 HydrophobicContact CG2-CD1 3.76Å; I338-I370 WeakPolarHBondContact O-CD1 3.28Å; I338-L372 HydrophobicContact CD1-CB 4.5Å; I338-L372 HydrophobicContact CD1-CD1 4.25Å; I338-L372 HydrophobicContact CD1-CD2 3.97Å; I338-L372 HydrophobicContact CD1-CG 4.48Å; I338-I414 HydrophobicContact CD1-CD1 4.22Å; I338-I414 HydrophobicContact CG2-CD1 4.01Å
339Y98.2Very high96.6Very high4 Ų413.2 Ų13.22%0.0167%0.074CC..EExtended strand (participates in β ladder)trans-153.3143.6-177.953.4-82.9000112.5L271 E287 L337 T341 I345 K346 L348L271-Y339 HydrophobicContact CD1-CD1 4Å; L271-Y339 HydrophobicContact CD1-CD2 3.84Å; L271-Y339 HydrophobicContact CD1-CE1 3.86Å; L271-Y339 HydrophobicContact CD1-CE2 3.69Å; L271-Y339 HydrophobicContact CD1-CG 4Å; E287-Y339 HydrophobicContact CG-CE2 3.85Å; E287-Y339 PolarHBondContact OE1-OH 3.09Å; L337-Y339 HydrophobicContact CB-CD1 4.46Å; L337-Y339 HydrophobicContact CD2-CD1 3.98Å; L337-Y339 HydrophobicContact CD2-CE1 4.23Å; L337-Y339 HydrophobicContact CG-CD1 4.01Å; L337-Y339 HydrophobicContact CG-CE1 4.48Å; Y339-T341 HydrophobicContact CD2-CG2 3.54Å; Y339-T341 HydrophobicContact CE2-CG2 3.6Å; Y339-I345 CarbonylContact O-C 3.57Å; Y339-K346 HydrophobicContact CD2-CB 4.33Å; Y339-K346 HydrophobicContact CE1-CB 4.27Å; Y339-K346 HydrophobicContact CE2-CB 3.85Å; Y339-K346 HydrophobicContact CE2-CD 3.92Å; Y339-K346 HydrophobicContact CE2-CG 4.38Å; Y339-K346 PolarHBondContact N-O 3.34Å; Y339-K346 PolarHBondContact O-N 2.89Å; Y339-L348 HydrophobicContact CE1-CB 3.72Å; Y339-L348 HydrophobicContact CE1-CD2 4.24Å
340P97.7Very high96.4Very high3 Ų312.4 Ų12.42%0.0197%0.069CC..EExtended strand (participates in β ladder)trans-84.8137.6179.429.4-24.3000111.5T326 K327 I345 R366 F367 L368 I370T326-P340 HydrophobicContact CG2-CG 4.14Å; K327-P340 WeakPolarHBondContact O-CD 3.33Å; P340-I345 HydrophobicContact CB-CG1 4.37Å; P340-R366 PolarHBondContact O-NH1 3.12Å; P340-F367 HydrophobicContact CB-CB 3.94Å; P340-F367 WeakPolarHBondContact CB-O 3.44Å; P340-L368 WeakPolarHBondContact CG-O 3.17Å; P340-I370 HydrophobicContact CB-CG2 4.36Å; P340-I370 HydrophobicContact CG-CG2 4.19Å
341T96.6Very high96.1Very high4 Ų416.1 Ų16.13%0.0259%0.086CC..  trans-132177.1-178.368.40000111.2E287 Y292 Y339 I343 G344 K346 R366E287-T341 HydrophobicContact CG-CG2 4.28Å; Y292-T341 WeakPolarHBondContact OH-CB 3.49Å; Y292-T341 WeakPolarHBondContact OH-CG2 3.36Å; Y292-T341 PolarHBondContact OH-OG1 2.88Å; Y339-T341 HydrophobicContact CD2-CG2 3.54Å; Y339-T341 HydrophobicContact CE2-CG2 3.6Å; T341-I343 PolarHBondContact O-N 2.94Å; T341-I343 PolarHBondContact OG1-N 3.01Å; T341-G344 PolarHBondContact N-O 2.82Å; T341-G344 PolarHBondContact O-N 3.31Å; T341-G344 PolarHBondContact OG1-N 2.98Å; T341-G344 PolarHBondContact OG1-O 2.7Å; T341-K346 HydrophobicContact CG2-CB 4.48Å; T341-K346 HydrophobicContact CG2-CD 3.9Å; T341-K346 HydrophobicContact CG2-CG 4.03Å; T341-R366 WeakPolarHBondContact O-CD 3.37Å; T341-R366 PolarHBondContact O-NE 3.45Å
342M95.3Very high95.9Very high4 Ų417.2 Ų17.22%0.029%0.093CC..SBendtrans-53.9-37.2172.6-175.2-175.879.600112.9L289 Y292 F306 K309 V310 E313L289-M342 HydrophobicContact CD1-SD 3.56Å; L289-M342 VanDerWaalsContact CD1-SD 3.56Å; Y292-M342 HydrophobicContact CD1-CE 3.93Å; Y292-M342 HydrophobicContact CD2-CB 4.29Å; Y292-M342 HydrophobicContact CD2-CE 4.21Å; Y292-M342 HydrophobicContact CE2-CB 4.16Å; Y292-M342 HydrophobicContact CG-CE 3.63Å; F306-M342 HydrophobicContact CD2-CE 4.41Å; F306-M342 HydrophobicContact CE2-CE 3.72Å; F306-M342 HydrophobicContact CZ-CE 3.96Å; K309-M342 HydrophobicContact CB-CG 3.96Å; K309-M342 HydrophobicContact CB-SD 4.47Å; V310-M342 HydrophobicContact CB-SD 4.48Å; V310-M342 HydrophobicContact CG2-CE 4.13Å; V310-M342 HydrophobicContact CG2-SD 3.86Å; E313-M342 HydrophobicContact CB-CB 4.43Å; E313-M342 HydrophobicContact CB-CG 3.93Å; E313-M342 HydrophobicContact CB-SD 3.98Å; E313-M342 HydrophobicContact CG-CB 4.1Å; E313-M342 HydrophobicContact CG-CG 4.15Å; E313-M342 HydrophobicContact CG-SD 4.27Å
343I95Very high96Very high0 Ų014.6 Ų14.60%08%0.079CC..SBendtrans-81.1-42.4-175.2-59.2-63.1000111.2Y292 Y299 L301 F306 K309 T341 I358 K361Y292-I343 HydrophobicContact CD1-CD1 4.04Å; Y292-I343 HydrophobicContact CD1-CG1 3.64Å; Y292-I343 HydrophobicContact CE1-CB 4.31Å; Y292-I343 HydrophobicContact CE1-CD1 4.14Å; Y292-I343 HydrophobicContact CE1-CG1 3.23Å; Y299-I343 HydrophobicContact CD1-CB 4.48Å; Y299-I343 HydrophobicContact CD1-CD1 4.3Å; Y299-I343 HydrophobicContact CD1-CG1 3.95Å; Y299-I343 HydrophobicContact CD1-CG2 3.97Å; Y299-I343 HydrophobicContact CD2-CD1 4.15Å; Y299-I343 HydrophobicContact CD2-CG1 4.4Å; Y299-I343 HydrophobicContact CE1-CG1 4Å; Y299-I343 HydrophobicContact CE2-CG1 4.47Å; Y299-I343 HydrophobicContact CG-CD1 3.99Å; Y299-I343 HydrophobicContact CG-CG1 4.14Å; L301-I343 HydrophobicContact CD1-CD1 3.69Å; L301-I343 HydrophobicContact CD1-CG2 4.33Å; F306-I343 HydrophobicContact CD2-CD1 4.43Å; F306-I343 HydrophobicContact CE2-CD1 4.23Å; K309-I343 PolarHBondContact NZ-O 3.44Å; T341-I343 PolarHBondContact O-N 2.94Å; T341-I343 PolarHBondContact OG1-N 3.01Å; I343-I358 HydrophobicContact CG2-CG2 4.06Å; I343-K361 HydrophobicContact CG2-CG 3.97Å; I343-K361 WeakPolarHBondContact O-CA 3.32Å
344G96.1Very high95.9Very high1 Ų116.9 Ų16.91%0.018%0.08CC..SBendtrans170.7-164-176.300000111.2T341 K346 L359T341-G344 PolarHBondContact N-O 2.82Å; T341-G344 PolarHBondContact O-N 3.31Å; T341-G344 PolarHBondContact OG1-N 2.98Å; T341-G344 PolarHBondContact OG1-O 2.7Å; G344-K346 PolarHBondContact O-N 3.12Å; G344-L359 CarbonylContact C-O 3.59Å; G344-L359 WeakPolarHBondContact CA-O 3.3Å
345I98.1Very high95.9Very high0 Ų017.6 Ų17.60%08%0.084CC..EExtended strand (participates in β ladder)trans-87.7107.2174.6-54.4171.9000108.1I338 Y339 P340 I358 L359 F367 I370 I414 F427I338-I345 HydrophobicContact CG2-CG2 3.48Å; I338-I345 VanDerWaalsContact CG2-CG2 3.48Å; Y339-I345 CarbonylContact O-C 3.57Å; P340-I345 HydrophobicContact CB-CG1 4.37Å; I345-I358 CarbonylContact O-C 3.51Å; I345-I358 WeakPolarHBondContact O-CA 3.34Å; I345-L359 HydrophobicContact CB-CB 4.24Å; I345-L359 PolarHBondContact N-O 3.06Å; I345-L359 PolarHBondContact O-N 2.84Å; I345-F367 HydrophobicContact CD1-CB 4.26Å; I345-F367 HydrophobicContact CD1-CD2 4.19Å; I345-F367 HydrophobicContact CD1-CG 4.07Å; I345-F367 HydrophobicContact CG1-CB 4.02Å; I345-F367 HydrophobicContact CG1-CD2 3.9Å; I345-F367 HydrophobicContact CG1-CG 4.06Å; I345-I370 HydrophobicContact CD1-CG2 3.94Å; I345-I370 HydrophobicContact CG1-CG2 4.38Å; I345-I370 HydrophobicContact CG2-CD1 4.25Å; I345-I414 HydrophobicContact CD1-CG2 4.33Å; I345-F427 HydrophobicContact CD1-CD2 3.93Å; I345-F427 HydrophobicContact CD1-CE2 3.61Å; I345-F427 HydrophobicContact CD1-CZ 4.25Å
346K97.7Very high95.8Very high4 Ų418 Ų182%0.0179%0.087CC..EExtended strand (participates in β ladder)trans-81142.4178.9-73.1-171.5175171.80110.5E287 Y292 I338 Y339 T341 G344 I358E287-K346 WeakPolarHBondContact OE1-CD 3.16Å; E287-K346 IonicContact OE1-NZ 3.88Å; E287-K346 PolarHBondContact OE1-NZ 2.79Å; E287-K346 IonicContact OE2-NZ 3.32Å; E287-K346 PolarHBondContact OE2-NZ 3.2Å; Y292-K346 WeakPolarHBondContact OH-CE 3.18Å; Y292-K346 PolarHBondContact OH-NZ 2.78Å; Y292-K346 VanDerWaalsContact OH-NZ 3.12Å; I338-K346 VanDerWaalsContact CA-O 3.32Å; I338-K346 WeakPolarHBondContact CA-O 3.43Å; Y339-K346 HydrophobicContact CD2-CB 4.33Å; Y339-K346 HydrophobicContact CE1-CB 4.27Å; Y339-K346 HydrophobicContact CE2-CB 3.85Å; Y339-K346 HydrophobicContact CE2-CD 3.92Å; Y339-K346 HydrophobicContact CE2-CG 4.38Å; Y339-K346 PolarHBondContact N-O 3.34Å; Y339-K346 PolarHBondContact O-N 2.89Å; T341-K346 HydrophobicContact CG2-CB 4.48Å; T341-K346 HydrophobicContact CG2-CD 3.9Å; T341-K346 HydrophobicContact CG2-CG 4.03Å; G344-K346 PolarHBondContact O-N 3.12Å; K346-I358 HydrophobicContact CG-CG1 4.27Å
347V98Very high95.7Very high0 Ų020.5 Ų20.50%010%0.097CC..EExtended strand (participates in β ladder)trans-114110.6169.2-175.20000107.2I42 F336 I338 C355 V356 R357I42-V347 HydrophobicContact CD1-CG1 3.76Å; I42-V347 HydrophobicContact CG2-CG1 4.31Å; I42-V347 HydrophobicContact CG2-CG2 3.92Å; F336-V347 HydrophobicContact CB-CG1 4Å; F336-V347 HydrophobicContact CD1-CG1 4.03Å; F336-V347 HydrophobicContact CG-CG1 4.2Å; I338-V347 HydrophobicContact CG1-CG1 4.41Å; I338-V347 HydrophobicContact CG1-CG2 4.43Å; I338-V347 HydrophobicContact CG2-CG2 4.45Å; V347-C355 CarbonylContact O-C 3.48Å; V347-C355 WeakPolarHBondContact O-CA 3.38Å; V347-V356 HydrophobicContact CB-CG2 4Å; V347-V356 HydrophobicContact CG1-CG2 3.67Å; V347-V356 VanDerWaalsContact O-CG2 3.31Å; V347-V356 WeakPolarHBondContact O-CG2 3.46Å; V347-V356 PolarHBondContact O-N 3.26Å; V347-R357 HydrophobicContact CB-CB 4.01Å; V347-R357 HydrophobicContact CG2-CB 3.94Å; V347-R357 PolarHBondContact N-O 3.02Å
348L97.4Very high95.6Very high0 Ų021.9 Ų21.90%010%0.104CC..EExtended strand (participates in β ladder)trans-102.1123.6-178.1173.973.6000109.8P16 F273 I285 F336 L337 Y339 V350P16-L348 HydrophobicContact CG-CD1 3.75Å; F273-L348 HydrophobicContact CZ-CD2 3.98Å; I285-L348 HydrophobicContact CD1-CD1 4.22Å; I285-L348 HydrophobicContact CD1-CD2 3.31Å; I285-L348 HydrophobicContact CD1-CG 4.41Å; F336-L348 CarbonylContact C-O 3.58Å; F336-L348 WeakPolarHBondContact CA-O 3.48Å; L337-L348 HydrophobicContact CB-CB 4.37Å; L337-L348 HydrophobicContact CB-CD2 4.42Å; L337-L348 PolarHBondContact N-O 2.84Å; L337-L348 PolarHBondContact O-N 2.85Å; Y339-L348 HydrophobicContact CE1-CB 3.72Å; Y339-L348 HydrophobicContact CE1-CD2 4.24Å; L348-V350 PolarHBondContact O-N 2.95Å
349N96.4Very high95.5Very high0 Ų022 Ų220%010%0.104CC..EExtended strand (participates in β ladder)trans-70.2116.6163.9-177.4-39.4000109.2L32 E35 F336 K351 T352 N353 R354 V356L32-N349 WeakPolarHBondContact CB-ND2 3.42Å; E35-N349 PolarHBondContact OE2-ND2 3.1Å; F336-N349 HydrophobicContact CD1-CB 4.05Å; F336-N349 HydrophobicContact CE1-CB 3.85Å; N349-K351 VanDerWaalsContact C-N 3.33Å; N349-K351 PolarHBondContact O-N 2.84Å; N349-K351 WeakPolarHBondContact OD1-CA 3.14Å; N349-K351 WeakPolarHBondContact OD1-CB 3.33Å; N349-K351 PolarHBondContact OD1-N 2.78Å; N349-T352 VanDerWaalsContact CB-OG1 3.3Å; N349-T352 WeakPolarHBondContact CB-OG1 3.3Å; N349-T352 PolarHBondContact OD1-N 3.5Å; N349-T352 PolarHBondContact OD1-OG1 3.01Å; N349-N353 VanDerWaalsContact O-CA 3.24Å; N349-N353 WeakPolarHBondContact O-CA 3.4Å; N349-N353 PolarHBondContact O-N 3.37Å; N349-R354 PolarHBondContact N-O 3.19Å; N349-V356 HydrophobicContact CB-CG1 3.99Å
350V94.1Very high95.4Very high14 Ų1421.8 Ų21.89%0.08510%0.103CC..THydrogen-bonded Turntrans-70.2-32.2-173.1177.60000111.5K283 Y330 N335 L337 L348 N353K283-V350 PolarHBondContact NZ-O 2.6Å; Y330-V350 HydrophobicContact CD1-CG2 4.29Å; Y330-V350 HydrophobicContact CE1-CG2 3.65Å; N335-V350 WeakPolarHBondContact O-CB 3.5Å; N335-V350 WeakPolarHBondContact O-CG2 3.42Å; N335-V350 PolarHBondContact O-N 3.46Å; L337-V350 HydrophobicContact CB-CG2 3.99Å; L348-V350 PolarHBondContact O-N 2.95Å; V350-N353 PolarHBondContact O-OD1 2.9Å
351K91.3Very high95.2Very high97 Ų9724.2 Ų24.242%0.42211%0.114SC..THydrogen-bonded Turntrans-76.6-40.6-179.1-171.7-178.6-174.8-175.10112R30 A31 L32 N349R30-K351 HydrophobicContact CB-CG 4.5Å; A31-K351 VanDerWaalsContact O-CE 3.29Å; A31-K351 WeakPolarHBondContact O-CE 3.23Å; A31-K351 PolarHBondContact O-NZ 3.24Å; L32-K351 HydrophobicContact CB-CD 4.26Å; L32-K351 HydrophobicContact CD1-CD 4.07Å; N349-K351 VanDerWaalsContact C-N 3.33Å; N349-K351 PolarHBondContact O-N 2.84Å; N349-K351 WeakPolarHBondContact OD1-CA 3.14Å; N349-K351 WeakPolarHBondContact OD1-CB 3.33Å; N349-K351 PolarHBondContact OD1-N 2.78Å
352T92.6Very high94.8Very high28 Ų2827.7 Ų27.717%0.17214%0.138CC..THydrogen-bonded Turntrans-98.7-11.9-174.673.10000113.4R30 N349 R354R30-T352 WeakPolarHBondContact O-CG2 3.36Å; N349-T352 VanDerWaalsContact CB-OG1 3.3Å; N349-T352 WeakPolarHBondContact CB-OG1 3.3Å; N349-T352 PolarHBondContact OD1-N 3.5Å; N349-T352 PolarHBondContact OD1-OG1 3.01Å; T352-R354 PolarHBondContact O-N 3.4Å; T352-R354 PolarHBondContact OG1-N 2.76Å
353N91.9Very high94.7Very high39 Ų3928.5 Ų28.521%0.20914%0.142CC..THydrogen-bonded Turntrans58.825.5-174.1-61.6-44.4000114.1P16 L18 K283 N349 V350P16-N353 WeakPolarHBondContact CD-O 3.25Å; L18-N353 HydrophobicContact CD2-CB 4.4Å; K283-N353 VanDerWaalsContact CD-OD1 3.23Å; K283-N353 WeakPolarHBondContact CD-OD1 3.46Å; K283-N353 PolarHBondContact NZ-OD1 3.21Å; N349-N353 VanDerWaalsContact O-CA 3.24Å; N349-N353 WeakPolarHBondContact O-CA 3.4Å; N349-N353 PolarHBondContact O-N 3.37Å; V350-N353 PolarHBondContact O-OD1 2.9Å
354R92.6Very high94.5Very high117 Ų11732 Ų3244%0.44216%0.161SC..EExtended strand (participates in β ladder)trans-100135.2178.4-66.7179.3172.5-172.2-10.2110.8N349 T352 V356N349-R354 PolarHBondContact N-O 3.19Å; T352-R354 PolarHBondContact O-N 3.4Å; T352-R354 PolarHBondContact OG1-N 2.76Å; R354-V356 PolarHBondContact O-N 3.49Å
355C94.2Very high94.4Very high20 Ų2032.9 Ų32.914%0.13517%0.165CC..EExtended strand (participates in β ladder)trans-75.1109.6167-165.90000107.6C14 V347 R357C14-C355 WeakPolarHBondContact O-CB 3.3Å; V347-C355 CarbonylContact O-C 3.48Å; V347-C355 WeakPolarHBondContact O-CA 3.38Å; C355-R357 PolarHBondContact SG-O 2.64Å
356V94.8Very high94.3Very high43 Ų4333.3 Ų33.326%0.26117%0.167SC..EExtended strand (participates in β ladder)trans-88.4-26.7-175.3-66.10000112.4L39 F336 V347 N349 R354L39-V356 HydrophobicContact CD2-CG2 3.75Å; F336-V356 HydrophobicContact CD1-CG2 3.99Å; F336-V356 HydrophobicContact CE1-CG2 3.91Å; V347-V356 HydrophobicContact CB-CG2 4Å; V347-V356 HydrophobicContact CG1-CG2 3.67Å; V347-V356 VanDerWaalsContact O-CG2 3.31Å; V347-V356 WeakPolarHBondContact O-CG2 3.46Å; V347-V356 PolarHBondContact O-N 3.26Å; N349-V356 HydrophobicContact CB-CG1 3.99Å; R354-V356 PolarHBondContact O-N 3.49Å
357R95.5Very high94.3Very high53 Ų5333.1 Ų33.120%0.217%0.166CC..EExtended strand (participates in β ladder)trans-146.3154.2176-60.6-175.2-177.9164.43.2111.6L39 I42 P43 V347 C355 L359L39-R357 PolarHBondContact O-NH1 2.77Å; L39-R357 VanDerWaalsContact O-NH1 3.15Å; L39-R357 PolarHBondContact O-NH2 3.28Å; L39-R357 VanDerWaalsContact O-NH2 3.07Å; I42-R357 PolarHBondContact O-NH1 2.68Å; P43-R357 VanDerWaalsContact C-NH1 3.31Å; P43-R357 PolarHBondContact O-NH1 3.28Å; V347-R357 HydrophobicContact CB-CB 4.01Å; V347-R357 HydrophobicContact CG2-CB 3.94Å; V347-R357 PolarHBondContact N-O 3.02Å; C355-R357 PolarHBondContact SG-O 2.64Å; R357-L359 HydrophobicContact CB-CD2 4.5Å
358I96.3Very high94.3Very high28 Ų2833.4 Ų33.414%0.14417%0.168CC..EExtended strand (participates in β ladder)trans-134102169.8-51.2-178000108.1Y299 I343 I345 K346 K361Y299-I358 HydrophobicContact CD1-CD1 4.46Å; Y299-I358 HydrophobicContact CE1-CD1 4.47Å; I343-I358 HydrophobicContact CG2-CG2 4.06Å; I345-I358 CarbonylContact O-C 3.51Å; I345-I358 WeakPolarHBondContact O-CA 3.34Å; K346-I358 HydrophobicContact CG-CG1 4.27Å; I358-K361 HydrophobicContact CG2-CB 4.07Å
359L96.7Very high94.3Very high2 Ų233.6 Ų33.61%0.0117%0.169CC..EExtended strand (participates in β ladder)trans-83.1146.3178.6-44.1174.9000110P43 A45 G344 I345 R357 K361 I414 F427P43-L359 HydrophobicContact CB-CD1 4.1Å; P43-L359 WeakPolarHBondContact O-CD2 3.46Å; A45-L359 WeakPolarHBondContact O-CD2 3.49Å; G344-L359 CarbonylContact C-O 3.59Å; G344-L359 WeakPolarHBondContact CA-O 3.3Å; I345-L359 HydrophobicContact CB-CB 4.24Å; I345-L359 PolarHBondContact N-O 3.06Å; I345-L359 PolarHBondContact O-N 2.84Å; R357-L359 HydrophobicContact CB-CD2 4.5Å; L359-K361 PolarHBondContact O-N 3.31Å; L359-I414 HydrophobicContact CD1-CD1 3.68Å; L359-F427 HydrophobicContact CB-CD1 3.85Å; L359-F427 HydrophobicContact CB-CE1 4.02Å; L359-F427 HydrophobicContact CB-CG 4.39Å; L359-F427 HydrophobicContact CD1-CB 4.27Å; L359-F427 HydrophobicContact CD1-CG 4.47Å
360G95.5Very high94.4Very high0 Ų033.8 Ų33.80%017%0.17CC..THydrogen-bonded Turntrans68.221.817900000113.9N46 S362 E363N46-G360 WeakPolarHBondContact O-CA 3.38Å; N46-G360 PolarHBondContact O-N 3.2Å; G360-S362 VanDerWaalsContact C-N 3.32Å; G360-S362 PolarHBondContact O-N 3.28Å; G360-E363 VanDerWaalsContact O-CB 3.3Å; G360-E363 WeakPolarHBondContact O-CB 3.42Å; G360-E363 PolarHBondContact O-N 3.18Å
361K93.2Very high94.6Very high55 Ų5533.5 Ų33.524%0.23917%0.169CC..THydrogen-bonded Turntrans-60-41.6-177.4-179.7179.4175.2-174.30112.4Y299 L301 K309 I343 I358 L359 E363Y299-K361 WeakPolarHBondContact O-CE 3.28Å; Y299-K361 PolarHBondContact O-NZ 2.86Å; L301-K361 HydrophobicContact CD2-CG 4.31Å; K309-K361 WeakPolarHBondContact CE-O 3.34Å; K309-K361 PolarHBondContact NZ-O 3.28Å; I343-K361 HydrophobicContact CG2-CG 3.97Å; I343-K361 WeakPolarHBondContact O-CA 3.32Å; I358-K361 HydrophobicContact CG2-CB 4.07Å; L359-K361 PolarHBondContact O-N 3.31Å; K361-E363 PolarHBondContact O-N 2.97Å
362S88.9Confident94.9Very high76 Ų7630.6 Ų30.653%0.53116%0.158SC..THydrogen-bonded Turntrans-74.3-11.5177.148.30000113.3G360G360-S362 VanDerWaalsContact C-N 3.32Å; G360-S362 PolarHBondContact O-N 3.28Å
363E92.4Very high95.1Very high21 Ų2129.6 Ų29.610%0.09815%0.152CC..  trans-81.1136.2-174.5-59.1-61158.500111.6A47 Y48 K309 G360 K361 V365 F367 R442A47-E363 VanDerWaalsContact CB-OE1 3.26Å; A47-E363 WeakPolarHBondContact CB-OE1 3.46Å; Y48-E363 HydrophobicContact CD1-CG 3.96Å; Y48-E363 VanDerWaalsContact CE1-CD 3.49Å; Y48-E363 HydrophobicContact CE1-CG 4.17Å; Y48-E363 VanDerWaalsContact CE1-OE2 3.25Å; Y48-E363 WeakPolarHBondContact CE1-OE2 3.38Å; K309-E363 WeakPolarHBondContact CE-O 3.46Å; K309-E363 PolarHBondContact NZ-O 2.99Å; G360-E363 VanDerWaalsContact O-CB 3.3Å; G360-E363 WeakPolarHBondContact O-CB 3.42Å; G360-E363 PolarHBondContact O-N 3.18Å; K361-E363 PolarHBondContact O-N 2.97Å; E363-V365 HydrophobicContact CB-CG2 3.6Å; E363-V365 HydrophobicContact CG-CG2 4.45Å; E363-V365 PolarHBondContact O-N 3.49Å; E363-F367 HydrophobicContact CB-CE2 4.24Å; E363-F367 HydrophobicContact CB-CZ 4.21Å; E363-F367 HydrophobicContact CG-CZ 4.31Å; E363-R442 IonicContact OE1-CZ 3.92Å; E363-R442 IonicContact OE1-NH1 3.49Å; E363-R442 IonicContact OE1-NH2 2.78Å; E363-R442 PolarHBondContact OE1-NH2 3.39Å; E363-R442 IonicContact OE2-NH1 2.63Å; E363-R442 IonicContact OE2-NH2 3.14Å
364N90.5Very high95Very high75 Ų7530.5 Ų30.540%0.40115%0.153SC..SBendtrans-86.331175-73.5-44.2000112.4
365V93.8Very high94.6Very high18 Ų1825.5 Ų25.511%0.10914%0.136CC..SBendtrans-118.9142.9176.8-89.70000110.7E363 F367 A418 K421E363-V365 HydrophobicContact CB-CG2 3.6Å; E363-V365 HydrophobicContact CG-CG2 4.45Å; E363-V365 PolarHBondContact O-N 3.49Å; V365-F367 HydrophobicContact CB-CE1 4.49Å; V365-F367 HydrophobicContact CB-CZ 4.39Å; V365-F367 HydrophobicContact CG2-CE1 3.83Å; V365-F367 HydrophobicContact CG2-CE2 4.08Å; V365-F367 HydrophobicContact CG2-CZ 3.44Å; V365-F367 VanDerWaalsContact CG2-CZ 3.44Å; V365-A418 HydrophobicContact CB-CB 4.21Å; V365-A418 HydrophobicContact CG1-CB 4.41Å; V365-K421 HydrophobicContact CG1-CD 4.35Å; V365-K421 HydrophobicContact CG1-CG 4.11Å
366R96.9Very high94.2Very high9 Ų927.3 Ų27.33%0.03415%0.146CC..  trans-98100174.7178.150.8167.4109.2-8.1109.6I312 E313 L316 P340 T341 A418 Y419I312-R366 HydrophobicContact CG2-CB 3.68Å; I312-R366 HydrophobicContact CG2-CG 4.37Å; E313-R366 IonicContact OE1-CZ 3.09Å; E313-R366 IonicContact OE1-NE 3.95Å; E313-R366 PolarHBondContact OE1-NE 2.68Å; E313-R366 IonicContact OE1-NH2 3.94Å; E313-R366 PolarHBondContact OE1-NH2 3.4Å; E313-R366 WeakPolarHBondContact OE2-CD 3.44Å; E313-R366 IonicContact OE2-CZ 3.45Å; E313-R366 IonicContact OE2-NE 2.7Å; E313-R366 PolarHBondContact OE2-NE 3.13Å; E313-R366 IonicContact OE2-NH2 3.86Å; L316-R366 HydrophobicContact CD2-CG 3.78Å; P340-R366 PolarHBondContact O-NH1 3.12Å; T341-R366 WeakPolarHBondContact O-CD 3.37Å; T341-R366 PolarHBondContact O-NE 3.45Å; R366-A418 CarbonylContact O-C 3.26Å; R366-A418 VanDerWaalsContact O-CA 3.28Å; R366-A418 WeakPolarHBondContact O-CA 3.36Å; R366-A418 WeakPolarHBondContact O-CB 3.39Å; R366-Y419 PolarHBondContact O-N 2.86Å
367F98Very high93.4Very high0 Ų029 Ų290%016%0.158CC..EExtended strand (participates in β ladder)trans-64.2151.5177.1-60.7-65000111.9P340 I345 E363 V365 S416 S417 A418 Y425 F427P340-F367 HydrophobicContact CB-CB 3.94Å; P340-F367 WeakPolarHBondContact CB-O 3.44Å; I345-F367 HydrophobicContact CD1-CB 4.26Å; I345-F367 HydrophobicContact CD1-CD2 4.19Å; I345-F367 HydrophobicContact CD1-CG 4.07Å; I345-F367 HydrophobicContact CG1-CB 4.02Å; I345-F367 HydrophobicContact CG1-CD2 3.9Å; I345-F367 HydrophobicContact CG1-CG 4.06Å; E363-F367 HydrophobicContact CB-CE2 4.24Å; E363-F367 HydrophobicContact CB-CZ 4.21Å; E363-F367 HydrophobicContact CG-CZ 4.31Å; V365-F367 HydrophobicContact CB-CE1 4.49Å; V365-F367 HydrophobicContact CB-CZ 4.39Å; V365-F367 HydrophobicContact CG2-CE1 3.83Å; V365-F367 HydrophobicContact CG2-CE2 4.08Å; V365-F367 HydrophobicContact CG2-CZ 3.44Å; V365-F367 VanDerWaalsContact CG2-CZ 3.44Å; F367-S416 WeakPolarHBondContact CB-OG 3.38Å; F367-S416 VanDerWaalsContact CD1-OG 3.23Å; F367-S416 WeakPolarHBondContact CD1-OG 3.37Å; F367-S417 CarbonylContact C-O 3.48Å; F367-S417 VanDerWaalsContact CA-O 3.26Å; F367-S417 WeakPolarHBondContact CA-O 3.3Å; F367-A418 HydrophobicContact CD1-CB 4.21Å; F367-Y425 HydrophobicContact CD1-CD2 4.19Å; F367-Y425 HydrophobicContact CE1-CD1 4.44Å; F367-Y425 AromaticContact CE1-CD2 3.76Å; F367-Y425 HydrophobicContact CE1-CD2 3.76Å; F367-Y425 HydrophobicContact CE1-CE2 4.37Å; F367-Y425 AromaticContact CE1-CG 3.82Å; F367-Y425 HydrophobicContact CE1-CG 3.82Å; F367-F427 HydrophobicContact CD1-CE2 4.35Å; F367-F427 HydrophobicContact CD2-CZ 4.48Å; F367-F427 AromaticContact CE1-CE2 3.87Å; F367-F427 HydrophobicContact CE1-CE2 3.87Å; F367-F427 AromaticContact CE1-CZ 3.97Å; F367-F427 HydrophobicContact CE1-CZ 3.97Å; F367-F427 HydrophobicContact CE2-CE2 4.25Å; F367-F427 AromaticContact CE2-CZ 3.72Å; F367-F427 HydrophobicContact CE2-CZ 3.72Å; F367-F427 AromaticContact CZ-CE2 3.83Å; F367-F427 HydrophobicContact CZ-CE2 3.83Å; F367-F427 AromaticContact CZ-CZ 3.43Å; F367-F427 HydrophobicContact CZ-CZ 3.43Å; F367-F427 VanDerWaalsContact CZ-CZ 3.43Å
368L97.5Very high92.3Very high6 Ų627.6 Ų27.63%0.03116%0.157CC..EExtended strand (participates in β ladder)trans-135.1-78.4-175.4-68.5177.8000113.7L316 F325 T326 K327 P340 S417 Y419L316-L368 HydrophobicContact CD1-CD1 4.25Å; L316-L368 HydrophobicContact CD1-CD2 3.89Å; L316-L368 HydrophobicContact CD2-CD2 3.66Å; L316-L368 HydrophobicContact CG-CD2 4.43Å; F325-L368 CarbonylContact O-C 3.5Å; T326-L368 WeakPolarHBondContact CA-O 3.09Å; K327-L368 PolarHBondContact N-O 2.91Å; P340-L368 WeakPolarHBondContact CG-O 3.17Å; L368-S417 PolarHBondContact N-O 3Å; L368-Y419 HydrophobicContact CD1-CD2 4.23Å
369C98.2Very high90.8Very high5 Ų532.4 Ų32.43%0.03419%0.187CC..EExtended strand (participates in β ladder)trans-83.6125.6175.5-166.70000108.1V61 F325 S416 S417V61-C369 HydrophobicContact CG2-CB 4.1Å; V61-C369 WeakPolarHBondContact CG2-O 3.44Å; V61-C369 PolarHBondContact N-SG 3.48Å; V61-C369 PolarHBondContact O-SG 3.24Å; F325-C369 VanDerWaalsContact O-CA 3.23Å; F325-C369 WeakPolarHBondContact O-CA 3.41Å; F325-C369 VanDerWaalsContact O-CB 3.22Å; F325-C369 WeakPolarHBondContact O-CB 3.42Å; F325-C369 PolarHBondContact O-N 3.25Å; C369-S416 CarbonylContact O-C 3.4Å; C369-S416 VanDerWaalsContact O-CA 3.3Å; C369-S416 WeakPolarHBondContact O-CA 3.49Å; C369-S417 WeakPolarHBondContact CA-OG 3.38Å; C369-S417 WeakPolarHBondContact CB-OG 3.35Å; C369-S417 PolarHBondContact N-OG 3.04Å; C369-S417 PolarHBondContact O-N 2.97Å; C369-S417 PolarHBondContact O-OG 3.1Å
370I98.1Very high88.6Confident4 Ų440.5 Ų40.52%0.02122%0.223CC..EExtended strand (participates in β ladder)trans-123.3149.7176.859.7168.8000110.7K327 V329 I338 P340 I345 I414 V415 S416K327-I370 WeakPolarHBondContact O-CG1 3.49Å; V329-I370 HydrophobicContact CG1-CG1 4.46Å; V329-I370 HydrophobicContact CG2-CD1 3.86Å; V329-I370 HydrophobicContact CG2-CG1 4.19Å; I338-I370 HydrophobicContact CB-CD1 4.24Å; I338-I370 HydrophobicContact CG2-CD1 3.76Å; I338-I370 WeakPolarHBondContact O-CD1 3.28Å; P340-I370 HydrophobicContact CB-CG2 4.36Å; P340-I370 HydrophobicContact CG-CG2 4.19Å; I345-I370 HydrophobicContact CD1-CG2 3.94Å; I345-I370 HydrophobicContact CG1-CG2 4.38Å; I345-I370 HydrophobicContact CG2-CD1 4.25Å; I370-I414 HydrophobicContact CB-CG2 4.42Å; I370-V415 CarbonylContact C-O 3.54Å; I370-V415 VanDerWaalsContact CA-O 3.3Å; I370-V415 WeakPolarHBondContact CA-O 3.35Å; I370-S416 WeakPolarHBondContact CG2-OG 3.13Å
371A98.1Very high86Confident8 Ų844.4 Ų44.47%0.06626%0.263CS..EExtended strand (participates in β ladder)trans-139130.4171.600000109.8V61 A63 I414 V415V61-A371 HydrophobicContact CG2-CB 4.26Å; A63-A371 HydrophobicContact CB-CB 3.94Å; A371-I414 WeakPolarHBondContact O-CA 3.21Å; A371-V415 PolarHBondContact N-O 3.16Å; A371-V415 PolarHBondContact O-N 3.01Å
372L97.3Very high83.1Confident35 Ų3546.9 Ų46.918%0.18328%0.282CS..EExtended strand (participates in β ladder)trans-87.1120.2172-17967.9000108.7V329 D331 I338 I414V329-L372 HydrophobicContact CG2-CB 4.49Å; D331-L372 HydrophobicContact CB-CD2 3.98Å; I338-L372 HydrophobicContact CD1-CB 4.5Å; I338-L372 HydrophobicContact CD1-CD1 4.25Å; I338-L372 HydrophobicContact CD1-CD2 3.97Å; I338-L372 HydrophobicContact CD1-CG 4.48Å; L372-I414 HydrophobicContact CD1-CD1 4.21Å; L372-I414 HydrophobicContact CD1-CG1 3.55Å
373C96Very high80.4Confident8 Ų852.7 Ų52.75%0.05430%0.301CS..EExtended strand (participates in β ladder)trans-79.3156.2172.8-59.30000110.4A63 K83 S375 M413A63-C373 HydrophobicContact CB-CB 4.44Å; K83-C373 HydrophobicContact CD-CB 3.91Å; C373-S375 PolarHBondContact O-N 3.45Å; C373-M413 HydrophobicContact CB-CB 4.03Å; C373-M413 WeakPolarHBondContact CB-O 3.47Å; C373-M413 PolarHBondContact N-O 3.06Å
374R90Very high77.3Confident57 Ų5755.9 Ų55.922%0.21533%0.326CS..PPolyproline II helixtrans-57.5133.8171.6-65.6-176.95875.7-2.4110.5R65 K83 H85 V376R65-R374 WeakPolarHBondContact O-CD 3.41Å; K83-R374 PolarHBondContact NZ-O 3.06Å; H85-R374 PolarHBondContact CE1-O 3.48Å; R374-V376 PolarHBondContact NE-O 3.43Å
375S85.3Confident74.4Confident13 Ų1355.9 Ų55.99%0.09134%0.344CS..SBendtrans-79.5-23175.659.20000112.9S41 C373 D411S41-S375 PolarHBondContact OG-OG 3.04Å; C373-S375 PolarHBondContact O-N 3.45Å; S375-D411 WeakPolarHBondContact CA-O 3.46Å; S375-D411 PolarHBondContact O-N 3.02Å
376V84.7Confident71.3Confident58 Ų5867.5 Ų67.535%0.35239%0.386SS..SBendtrans-123.4145.2178.3-65.10000110.8H85 R374 P410H85-V376 PolarHBondContact CE1-O 3.18Å; R374-V376 PolarHBondContact NE-O 3.43Å; V376-P410 HydrophobicContact CG1-CB 4.47Å
377P79.6Confident68.1Low79 Ų7970.1 Ų70.151%0.51342%0.416SS..  trans-49.7142.3179.3-28.133.4000113.4H85H85-P377 HydrophobicContact CB-CG 4.17Å; H85-P377 VanDerWaalsContact CE1-N 3.29Å; H85-P377 WeakPolarHBondContact NE2-CA 3.17Å
378S71.3Confident64.7Low23 Ų2379.3 Ų79.316%0.16146%0.459CS..  trans-64.6141.6168.663.20000110.5R65 D67 F380R65-S378 WeakPolarHBondContact O-CB 3.23Å; D67-S378 WeakPolarHBondContact OD2-CB 3.5Å; D67-S378 PolarHBondContact OD2-N 3.1Å; D67-S378 PolarHBondContact OD2-OG 2.84Å; S378-F380 VanDerWaalsContact C-N 3.35Å
379T65.9Low61.6Low129 Ų12983.7 Ų83.779%0.79150%0.496SS*.  trans-90.2-3173.150.50000112.5
380F49.9Very low58.7Low172 Ų17287 Ų8775%0.75452%0.523SS*.SBendtrans-90.2129-179.4-85.1-87.1000111S378S378-F380 VanDerWaalsContact C-N 3.35Å
381G40.3Very low55.8Low82 Ų8290.9 Ų90.985%0.84556%0.556SS**SBendtrans97-3.7169.200000116.7E383G381-E383 PolarHBondContact O-N 2.86Å
382V33Very low53.4Low106 Ų10695.1 Ų95.164%0.64259%0.591SS**  trans-89.888171-174.20000109.2S384V382-S384 VanDerWaalsContact CG1-CB 3.49Å; V382-S384 WeakPolarHBondContact CG1-OG 3.48Å; V382-S384 PolarHBondContact O-N 2.94Å
383E31.1Very low51.4Low198 Ų19896.1 Ų96.193%0.92560%0.596SS**  trans-69.178.5153.6-74.6-168.8173.300107.9G381G381-E383 PolarHBondContact O-N 2.86Å
384S27.7Very low49.8Very low88 Ų8898.9 Ų98.962%0.61561%0.612SS**  trans-142.4112.8169-560000108.5V382V382-S384 VanDerWaalsContact CG1-CB 3.49Å; V382-S384 WeakPolarHBondContact CG1-OG 3.48Å; V382-S384 PolarHBondContact O-N 2.94Å
385G30.3Very low48.5Very low76 Ų7699.9 Ų99.978%0.78462%0.62SS**SBendtrans-51.8149.6-175.700000113.2
386R28.2Very low47.6Very low262 Ų262106.2 Ų106.299%0.98965%0.648SS**  trans73.459173.9-55.6-179.6169.2178.9-3.1115.6
387G29.8Very low46.6Very low64 Ų64107.9 Ų107.966%0.6665%0.653SS**  trans-129.1105.215100000108A389G387-A389 PolarHBondContact O-N 2.61Å; G387-A389 VanDerWaalsContact O-N 3.15Å
388Q27.6Very low45.7Very low193 Ų193107.4 Ų107.490%0.90264%0.644SS**  trans-47.2124.8164.7-72.3165.8-15.800106.8A390Q388-A390 VanDerWaalsContact C-N 3.34Å; Q388-A390 PolarHBondContact O-N 3.34Å
389A31.4Very low45.3Very low98 Ų98108.6 Ų108.681%0.8166%0.656SS**  trans-46.5108.9167.300000105.8G387 A391G387-A389 PolarHBondContact O-N 2.61Å; G387-A389 VanDerWaalsContact O-N 3.15Å; A389-A391 PolarHBondContact O-N 3.08Å
390A37.7Very low45.3Very low75 Ų75105.1 Ų105.162%0.6264%0.637SS**  trans-55.3109.3-176.100000105.3Q388 A392Q388-A390 VanDerWaalsContact C-N 3.34Å; Q388-A390 PolarHBondContact O-N 3.34Å; A390-A392 PolarHBondContact O-N 2.77Å; A390-A392 VanDerWaalsContact O-N 3.08Å
391A36.6Very low45.8Very low85 Ų85103.7 Ų103.770%0.70264%0.637SS**  trans-49.1124.3177.600000106A389 I393A389-A391 PolarHBondContact O-N 3.08Å; A391-I393 PolarHBondContact O-N 2.47Å
392A47.2Very low47Very low96 Ų96102.8 Ų102.879%0.79361%0.613SS**  trans-47.4106.7-173.100000108.9A390 T394A390-A392 PolarHBondContact O-N 2.77Å; A390-A392 VanDerWaalsContact O-N 3.08Å; A392-T394 PolarHBondContact O-N 3.12Å
393I56.4Low48.2Very low57 Ų57102.5 Ų102.529%0.29261%0.613SS.*  trans-64.6121.3-177.9-62.9156.5000104.9A391 M397 E398 L405A391-I393 PolarHBondContact O-N 2.47Å; I393-M397 HydrophobicContact CG2-CB 3.8Å; I393-E398 HydrophobicContact CG2-CB 4.01Å; I393-L405 HydrophobicContact CD1-CD2 3.67Å; I393-L405 HydrophobicContact CG1-CD2 3.92Å; I393-L405 HydrophobicContact CG2-CD1 4.05Å; I393-L405 HydrophobicContact CG2-CD2 4.14Å
394T62Low49.6Very low65 Ų6599.8 Ų99.840%0.39960%0.603SS.*  trans-66.8147.8175.564.70000108.4A392 E396 M397 E398A392-T394 PolarHBondContact O-N 3.12Å; T394-E396 PolarHBondContact O-N 3.41Å; T394-E396 VanDerWaalsContact O-N 3.11Å; T394-M397 HydrophobicContact CG2-SD 4.46Å; T394-M397 WeakPolarHBondContact O-CA 3.2Å; T394-M397 WeakPolarHBondContact O-CB 3.38Å; T394-M397 PolarHBondContact O-N 3.18Å; T394-M397 WeakPolarHBondContact OG1-CG 3.44Å; T394-M397 PolarHBondContact OG1-N 3.13Å; T394-E398 PolarHBondContact O-N 3.22Å
395M62.8Low50.9Low79 Ų7997.3 Ų97.339%0.38958%0.583SS.*Hα-helixtrans-55.5-32.1177.4-82.9-171.5-92.100112.6F34 Y38 E398 A399F34-M395 HydrophobicContact CD2-SD 4.4Å; Y38-M395 HydrophobicContact CE1-CE 4.39Å; Y38-M395 HydrophobicContact CE1-SD 3.56Å; Y38-M395 VanDerWaalsContact CE1-SD 3.56Å; Y38-M395 HydrophobicContact CE2-SD 4.27Å; Y38-M395 WeakPolarHBondContact OH-CE 3.44Å; Y38-M395 PolarHBondContact OH-SD 2.84Å; M395-E398 PolarHBondContact O-N 3.23Å; M395-A399 VanDerWaalsContact O-CB 3.25Å; M395-A399 WeakPolarHBondContact O-CB 3.44Å; M395-A399 PolarHBondContact O-N 3.41Å
396E66.4Low51.9Low145 Ų14599.9 Ų99.968%0.67857%0.573SS**Hα-helixtrans-65-38.2174.1-63.5164.9172.700112.1T394 S400T394-E396 PolarHBondContact O-N 3.41Å; T394-E396 VanDerWaalsContact O-N 3.11Å; E396-S400 PolarHBondContact O-N 2.81Å; E396-S400 VanDerWaalsContact O-N 3.12Å
397M63.4Low53Low93 Ų9398.6 Ų98.646%0.45857%0.568SS.*Hα-helixtrans-69.1-38.9173.8-74.1173.272.300111.5I393 T394 S400 L405I393-M397 HydrophobicContact CG2-CB 3.8Å; T394-M397 HydrophobicContact CG2-SD 4.46Å; T394-M397 WeakPolarHBondContact O-CA 3.2Å; T394-M397 WeakPolarHBondContact O-CB 3.38Å; T394-M397 PolarHBondContact O-N 3.18Å; T394-M397 WeakPolarHBondContact OG1-CG 3.44Å; T394-M397 PolarHBondContact OG1-N 3.13Å; M397-S400 WeakPolarHBondContact O-CB 3.25Å; M397-S400 PolarHBondContact O-N 2.85Å; M397-S400 PolarHBondContact O-OG 2.72Å; M397-L405 HydrophobicContact CB-CD1 4.44Å; M397-L405 WeakPolarHBondContact O-CD1 3.32Å
398E62Low54.5Low69 Ų6999.8 Ų99.832%0.32256%0.559SS.*Hα-helixtrans-70.5-32.8176.1-163.4177-178.800112.5I37 I393 T394 M395 S400I37-E398 HydrophobicContact CG2-CG 4.37Å; I393-E398 HydrophobicContact CG2-CB 4.01Å; T394-E398 PolarHBondContact O-N 3.22Å; M395-E398 PolarHBondContact O-N 3.23Å; E398-S400 PolarHBondContact O-N 3Å
399A62.2Low56.7Low48 Ų4895.2 Ų95.240%0.39754%0.541SS..Hα-helixtrans-68-25.6172.100000112.6F34 I37 M395F34-A399 HydrophobicContact CD1-CB 4.34Å; F34-A399 HydrophobicContact CE1-CB 4.32Å; I37-A399 HydrophobicContact CD1-CB 3.49Å; I37-A399 VanDerWaalsContact CD1-CB 3.49Å; M395-A399 VanDerWaalsContact O-CB 3.25Å; M395-A399 WeakPolarHBondContact O-CB 3.44Å; M395-A399 PolarHBondContact O-N 3.41Å
400S66Low59.3Low57 Ų5791.4 Ų91.440%0.39951%0.508SS..SBendtrans-75.4125.7172.279.30000109E396 M397 E398 N402E396-S400 PolarHBondContact O-N 2.81Å; E396-S400 VanDerWaalsContact O-N 3.12Å; M397-S400 WeakPolarHBondContact O-CB 3.25Å; M397-S400 PolarHBondContact O-N 2.85Å; M397-S400 PolarHBondContact O-OG 2.72Å; E398-S400 PolarHBondContact O-N 3Å; S400-N402 PolarHBondContact O-N 3.47Å
401D60.2Low61.8Low141 Ų14188.8 Ų88.875%0.75448%0.484SS*.  trans-67.355.2179.8-85.3-36.7000112.6P403D401-P403 WeakPolarHBondContact O-CD 3.39Å
402N64.6Low64.5Low63 Ų6384.8 Ų84.834%0.33745%0.45SS..  trans-81.8116.9-177.7-167.6-22.7000109.5S400 I404 L405S400-N402 PolarHBondContact O-N 3.47Å; N402-I404 PolarHBondContact O-N 3.44Å; N402-I404 PolarHBondContact OD1-N 3.24Å; N402-L405 HydrophobicContact CB-CD1 3.99Å; N402-L405 HydrophobicContact CB-CG 4.15Å; N402-L405 PolarHBondContact O-N 3.45Å
403P59.1Low66.9Low101 Ų10180.3 Ų80.366%0.65641%0.413SS*.THydrogen-bonded Turntrans-57.8-25.9-175.9-24.233.1000114.3D401 L405 K406D401-P403 WeakPolarHBondContact O-CD 3.39Å; P403-L405 VanDerWaalsContact C-N 3.27Å; P403-L405 PolarHBondContact O-N 3.39Å; P403-K406 PolarHBondContact O-N 3.16Å
404I60.1Low68.9Low140 Ų14077.7 Ų77.772%0.71840%0.399SS*.THydrogen-bonded Turntrans-67.8-30.4179.7-59.6170.5000111N402N402-I404 PolarHBondContact O-N 3.44Å; N402-I404 PolarHBondContact OD1-N 3.24Å
405L55.7Low70.6Confident36 Ų3674.6 Ų74.619%0.18838%0.381CS..G310 helixtrans-81.2-21.3-177.5-62177.6000113.3I393 M397 N402 P403 R407 N408I393-L405 HydrophobicContact CD1-CD2 3.67Å; I393-L405 HydrophobicContact CG1-CD2 3.92Å; I393-L405 HydrophobicContact CG2-CD1 4.05Å; I393-L405 HydrophobicContact CG2-CD2 4.14Å; M397-L405 HydrophobicContact CB-CD1 4.44Å; M397-L405 WeakPolarHBondContact O-CD1 3.32Å; N402-L405 HydrophobicContact CB-CD1 3.99Å; N402-L405 HydrophobicContact CB-CG 4.15Å; N402-L405 PolarHBondContact O-N 3.45Å; P403-L405 VanDerWaalsContact C-N 3.27Å; P403-L405 PolarHBondContact O-N 3.39Å; L405-R407 PolarHBondContact O-N 3.05Å; L405-N408 PolarHBondContact O-N 3.24Å
406K50.5Low72.3Confident131 Ų13170.8 Ų70.857%0.5736%0.362SS*.G310 helixtrans-58.2-18.2178.1-70.7-167.1174.6-171.20114.1P403 N408 D409P403-K406 PolarHBondContact O-N 3.16Å; K406-N408 PolarHBondContact O-N 3.2Å; K406-D409 PolarHBondContact O-N 3.22Å
407R51.8Low73.8Confident235 Ų23564 Ų6489%0.88733%0.33SS*.G310 helixtrans-63.8-16.4174.1-125.3-178.6-175.1-178.90.6113.3L405L405-R407 PolarHBondContact O-N 3.05Å
408N61.3Low75.4Confident89 Ų8959.6 Ų59.648%0.47631%0.309SS..G310 helixtrans-111.330.5178.9-69.4-5.1000112.2L405 K406 P410L405-N408 PolarHBondContact O-N 3.24Å; K406-N408 PolarHBondContact O-N 3.2Å; N408-P410 WeakPolarHBondContact O-CD 3.43Å
409D73.9Confident77.1Confident96 Ų9656.9 Ų56.951%0.51330%0.296SS..  trans-56.2126.3173.7-83.6-19.8000109.4K406K406-D409 PolarHBondContact O-N 3.22Å
410P85.1Confident78.6Confident18 Ų1860 Ų6012%0.11730%0.3CS..  trans-64.8138.6-178.223.7-32.4000110.7R40 V376 N408 P412R40-P410 HydrophobicContact CB-CG 3.56Å; R40-P410 WeakPolarHBondContact O-CG 3.07Å; V376-P410 HydrophobicContact CG1-CB 4.47Å; N408-P410 WeakPolarHBondContact O-CD 3.43Å; P410-P412 VanDerWaalsContact C-CD 3.44Å; P410-P412 WeakPolarHBondContact O-CD 3.5Å
411D90.1Very high80Confident21 Ų2161.4 Ų61.411%0.11230%0.299CS..  trans-106.378.9173.1173.133.5000109.2K83 H85 N86 S375K83-D411 WeakPolarHBondContact CE-OD2 3.48Å; K83-D411 PolarHBondContact NZ-O 2.8Å; K83-D411 IonicContact NZ-OD2 3.81Å; K83-D411 PolarHBondContact NZ-OD2 2.87Å; K83-D411 VanDerWaalsContact NZ-OD2 3.15Å; H85-D411 VanDerWaalsContact CA-OD2 3.32Å; H85-D411 WeakPolarHBondContact CA-OD2 3.36Å; N86-D411 PolarHBondContact N-OD2 3.3Å; S375-D411 WeakPolarHBondContact CA-O 3.46Å; S375-D411 PolarHBondContact O-N 3.02Å
412P94.2Very high81.7Confident0 Ų057.3 Ų57.30%028%0.277CS..  trans-74139.9-175.734.6-39.9000111.6R40 S41 I42 P43 P410 N429R40-P412 WeakPolarHBondContact O-CG 3.27Å; S41-P412 WeakPolarHBondContact O-CB 3.5Å; I42-P412 VanDerWaalsContact C-CB 3.45Å; P43-P412 HydrophobicContact CG-CB 4.18Å; P410-P412 VanDerWaalsContact C-CD 3.44Å; P410-P412 WeakPolarHBondContact O-CD 3.5Å; P412-N429 WeakPolarHBondContact CD-ND2 3.31Å; P412-N429 WeakPolarHBondContact CG-ND2 3.21Å
413M96.6Very high83.2Confident3 Ų356 Ų562%0.01527%0.267CS..EExtended strand (participates in β ladder)trans-141.9134.3177.3-179.8-174.8-66.800110.9I69 K83 I89 C373 L426 F427 T428I69-M413 HydrophobicContact CD1-SD 4.03Å; K83-M413 HydrophobicContact CD-CE 4.49Å; K83-M413 HydrophobicContact CD-SD 4.38Å; K83-M413 HydrophobicContact CG-CE 4.24Å; K83-M413 HydrophobicContact CG-SD 4.35Å; I89-M413 HydrophobicContact CG2-CE 3.95Å; I89-M413 HydrophobicContact CG2-SD 3.74Å; C373-M413 HydrophobicContact CB-CB 4.03Å; C373-M413 WeakPolarHBondContact CB-O 3.47Å; C373-M413 PolarHBondContact N-O 3.06Å; M413-L426 HydrophobicContact SD-CD1 4.46Å; M413-L426 HydrophobicContact SD-CD2 4.23Å; M413-F427 CarbonylContact C-O 3.55Å; M413-F427 VanDerWaalsContact CA-O 3.29Å; M413-F427 WeakPolarHBondContact CA-O 3.48Å; M413-T428 HydrophobicContact CB-CG2 4.5Å; M413-T428 HydrophobicContact CE-CG2 4.15Å; M413-T428 HydrophobicContact CG-CG2 4.26Å
414I98.1Very high85Confident1 Ų151.1 Ų51.11%0.00524%0.236CC..EExtended strand (participates in β ladder)trans-113.6130.6167.9-71.3165000108.5I42 P43 I338 I345 L359 I370 A371 L372 L426 F427I42-I414 HydrophobicContact CG2-CD1 4.41Å; P43-I414 HydrophobicContact CG-CB 4.16Å; P43-I414 HydrophobicContact CG-CD1 3.94Å; P43-I414 HydrophobicContact CG-CG1 3.81Å; I338-I414 HydrophobicContact CD1-CD1 4.22Å; I338-I414 HydrophobicContact CG2-CD1 4.01Å; I345-I414 HydrophobicContact CD1-CG2 4.33Å; L359-I414 HydrophobicContact CD1-CD1 3.68Å; I370-I414 HydrophobicContact CB-CG2 4.42Å; A371-I414 WeakPolarHBondContact O-CA 3.21Å; L372-I414 HydrophobicContact CD1-CD1 4.21Å; L372-I414 HydrophobicContact CD1-CG1 3.55Å; I414-L426 WeakPolarHBondContact O-CA 3.32Å; I414-F427 HydrophobicContact CB-CB 4.24Å; I414-F427 PolarHBondContact N-O 3.03Å; I414-F427 PolarHBondContact O-N 3.07Å
415V98.1Very high86.8Confident0 Ų044.9 Ų44.90%020%0.203CC..EExtended strand (participates in β ladder)trans-100.9136.2171.8-172.30000108.1V61 I69 I370 A371 F424 Y425 L426V61-V415 HydrophobicContact CB-CG1 3.97Å; V61-V415 HydrophobicContact CG1-CG1 4.02Å; V61-V415 HydrophobicContact CG2-CG1 4.43Å; I69-V415 HydrophobicContact CD1-CG2 3.81Å; I69-V415 HydrophobicContact CG1-CG2 4.09Å; I69-V415 HydrophobicContact CG2-CB 4.43Å; I69-V415 HydrophobicContact CG2-CG1 4.11Å; I69-V415 HydrophobicContact CG2-CG2 3.89Å; I370-V415 CarbonylContact C-O 3.54Å; I370-V415 VanDerWaalsContact CA-O 3.3Å; I370-V415 WeakPolarHBondContact CA-O 3.35Å; A371-V415 PolarHBondContact N-O 3.16Å; A371-V415 PolarHBondContact O-N 3.01Å; V415-F424 HydrophobicContact CG1-CD2 3.69Å; V415-F424 HydrophobicContact CG1-CE2 4.31Å; V415-F424 HydrophobicContact CG1-CG 4.45Å; V415-Y425 CarbonylContact C-O 3.22Å; V415-Y425 WeakPolarHBondContact CA-O 3.11Å; V415-L426 HydrophobicContact CB-CD2 4.33Å; V415-L426 HydrophobicContact CG1-CD2 4.14Å; V415-L426 HydrophobicContact CG2-CD2 3.77Å
416S98.4Very high88.8Confident0 Ų043.4 Ų43.40%020%0.196CC..EExtended strand (participates in β ladder)trans-140.2141-177.1-172.80000112.6F367 C369 I370 F424 Y425F367-S416 WeakPolarHBondContact CB-OG 3.38Å; F367-S416 VanDerWaalsContact CD1-OG 3.23Å; F367-S416 WeakPolarHBondContact CD1-OG 3.37Å; C369-S416 CarbonylContact O-C 3.4Å; C369-S416 VanDerWaalsContact O-CA 3.3Å; C369-S416 WeakPolarHBondContact O-CA 3.49Å; I370-S416 WeakPolarHBondContact CG2-OG 3.13Å; S416-F424 CarbonylContact O-C 3.58Å; S416-F424 WeakPolarHBondContact O-CA 3.49Å; S416-F424 WeakPolarHBondContact O-CB 3.44Å; S416-Y425 PolarHBondContact N-O 3.4Å; S416-Y425 WeakPolarHBondContact O-CD2 3.49Å; S416-Y425 PolarHBondContact O-N 3.29Å
417S98.1Very high91Very high1 Ų137.1 Ų37.11%0.00717%0.169CC..EExtended strand (participates in β ladder)trans-91.3166.5162.561.50000110.4V58 F367 L368 C369V58-S417 WeakPolarHBondContact O-CB 3.32Å; F367-S417 CarbonylContact C-O 3.48Å; F367-S417 VanDerWaalsContact CA-O 3.26Å; F367-S417 WeakPolarHBondContact CA-O 3.3Å; L368-S417 PolarHBondContact N-O 3Å; C369-S417 WeakPolarHBondContact CA-OG 3.38Å; C369-S417 WeakPolarHBondContact CB-OG 3.35Å; C369-S417 PolarHBondContact N-OG 3.04Å; C369-S417 PolarHBondContact O-N 2.97Å; C369-S417 PolarHBondContact O-OG 3.1Å
418A97.6Very high93.1Very high1 Ų126.1 Ų26.11%0.00813%0.128CC..EExtended strand (participates in β ladder)trans-138.4154.4174.400000112.9V365 R366 F367 K420 K421 Y425V365-A418 HydrophobicContact CB-CB 4.21Å; V365-A418 HydrophobicContact CG1-CB 4.41Å; R366-A418 CarbonylContact O-C 3.26Å; R366-A418 VanDerWaalsContact O-CA 3.28Å; R366-A418 WeakPolarHBondContact O-CA 3.36Å; R366-A418 WeakPolarHBondContact O-CB 3.39Å; F367-A418 HydrophobicContact CD1-CB 4.21Å; A418-K420 PolarHBondContact O-N 2.93Å; A418-K421 HydrophobicContact CB-CB 4.07Å; A418-K421 HydrophobicContact CB-CG 3.82Å; A418-K421 PolarHBondContact O-N 2.94Å; A418-K421 VanDerWaalsContact O-N 3.1Å; A418-Y425 HydrophobicContact CB-CD2 4.2Å; A418-Y425 HydrophobicContact CB-CE2 3.54Å
419Y97.1Very high94.5Very high13 Ų1325.5 Ų25.55%0.05112%0.124CC..THydrogen-bonded Turntrans-55.9124.3-179.7-178.6-120000111.9I312 E315 L316 R366 L368 K421I312-Y419 HydrophobicContact CG2-CD1 3.98Å; E315-Y419 HydrophobicContact CB-CE1 4.49Å; E315-Y419 HydrophobicContact CG-CE1 4.3Å; L316-Y419 HydrophobicContact CB-CE1 4.48Å; L316-Y419 HydrophobicContact CB-CE2 4.46Å; L316-Y419 HydrophobicContact CD1-CD2 3.5Å; L316-Y419 HydrophobicContact CD1-CE2 3.77Å; L316-Y419 HydrophobicContact CD1-CG 4.06Å; R366-Y419 PolarHBondContact O-N 2.86Å; L368-Y419 HydrophobicContact CD1-CD2 4.23Å; Y419-K421 PolarHBondContact O-N 3.24Å
420K94.6Very high95.2Very high114 Ų11424 Ų2450%0.49612%0.121SC..THydrogen-bonded Turntrans55.926.9-177.9-64-176.2168.6-175.10114.5E315 A418E315-K420 IonicContact OE1-NZ 2.77Å; E315-K420 PolarHBondContact OE1-NZ 2.94Å; A418-K420 PolarHBondContact O-N 2.93Å
421K95.9Very high95.2Very high86 Ų8627.2 Ų27.237%0.37413%0.134SC..  trans-109.7130.4176.3-60.8-59.2-176.2-178.20110.6V57 V58 V365 A418 Y419 R423 Y425V57-K421 WeakPolarHBondContact CA-O 3.32Å; V58-K421 PolarHBondContact N-O 3.43Å; V365-K421 HydrophobicContact CG1-CD 4.35Å; V365-K421 HydrophobicContact CG1-CG 4.11Å; A418-K421 HydrophobicContact CB-CB 4.07Å; A418-K421 HydrophobicContact CB-CG 3.82Å; A418-K421 PolarHBondContact O-N 2.94Å; A418-K421 VanDerWaalsContact O-N 3.1Å; Y419-K421 PolarHBondContact O-N 3.24Å; K421-R423 PolarHBondContact O-N 3.14Å; K421-Y425 HydrophobicContact CB-CE2 4.35Å; K421-Y425 WeakPolarHBondContact CG-OH 3.41Å
422N95.3Very high94.8Very high55 Ų5527.5 Ų27.529%0.29414%0.137SC..SBendtrans-81.525.6167.865.7-25000112.1M53 H54 D56M53-N422 WeakPolarHBondContact CA-O 3.41Å; M53-N422 WeakPolarHBondContact CE-ND2 3.31Å; H54-N422 PolarHBondContact N-O 2.83Å; D56-N422 VanDerWaalsContact O-CA 3.26Å; D56-N422 WeakPolarHBondContact O-CA 3.32Å; D56-N422 VanDerWaalsContact O-CB 3.29Å; D56-N422 WeakPolarHBondContact O-CB 3.4Å
423R95.5Very high93.6Very high34 Ų3433.2 Ų33.213%0.12816%0.162CC..EExtended strand (participates in β ladder)trans-132.5149.2-178.1-73176.8171-85.72.8110.4S51 F52 M53 K421 Y425 V444S51-R423 PolarHBondContact OG-NH1 2.92Å; F52-R423 CarbonylContact O-C 3.54Å; F52-R423 WeakPolarHBondContact O-CA 3.38Å; F52-R423 WeakPolarHBondContact O-CB 3.16Å; M53-R423 HydrophobicContact CG-CG 3.89Å; M53-R423 PolarHBondContact SD-NH2 2.83Å; K421-R423 PolarHBondContact O-N 3.14Å; R423-Y425 HydrophobicContact CB-CE2 4.36Å; R423-Y425 WeakPolarHBondContact O-CE2 3.44Å; R423-V444 PolarHBondContact NH1-O 3.33Å
424F97.8Very high91.6Very high0 Ų040.1 Ų40.10%021%0.205CC..EExtended strand (participates in β ladder)trans-112.3156.216369.3-88.8000110.2S51 F52 V58 V61 T71 W81 I89 V415 S416 L426S51-F424 CarbonylContact C-O 3.49Å; S51-F424 WeakPolarHBondContact CA-O 3.46Å; S51-F424 WeakPolarHBondContact CB-O 3.43Å; F52-F424 HydrophobicContact CB-CD1 4.09Å; F52-F424 HydrophobicContact CB-CE1 3.42Å; F52-F424 VanDerWaalsContact CB-CE1 3.42Å; F52-F424 HydrophobicContact CB-CE2 4.06Å; F52-F424 HydrophobicContact CB-CZ 3.41Å; F52-F424 VanDerWaalsContact CB-CZ 3.41Å; F52-F424 AromaticContact CD2-CE2 3.88Å; F52-F424 HydrophobicContact CD2-CE2 3.88Å; F52-F424 AromaticContact CD2-CZ 3.93Å; F52-F424 HydrophobicContact CD2-CZ 3.93Å; F52-F424 HydrophobicContact CG-CE1 4.35Å; F52-F424 HydrophobicContact CG-CE2 4.29Å; F52-F424 AromaticContact CG-CZ 3.86Å; F52-F424 HydrophobicContact CG-CZ 3.86Å; F52-F424 PolarHBondContact N-O 3.15Å; F52-F424 PolarHBondContact O-N 2.68Å; V58-F424 HydrophobicContact CG1-CB 4.34Å; V61-F424 HydrophobicContact CG1-CB 4.17Å; T71-F424 HydrophobicContact CG2-CD1 3.85Å; T71-F424 HydrophobicContact CG2-CD2 4.19Å; T71-F424 HydrophobicContact CG2-CE1 3.89Å; T71-F424 HydrophobicContact CG2-CE2 4.23Å; T71-F424 HydrophobicContact CG2-CG 3.98Å; T71-F424 HydrophobicContact CG2-CZ 4.06Å; W81-F424 AromaticContact CD2-CZ 3.97Å; W81-F424 HydrophobicContact CD2-CZ 3.97Å; W81-F424 AromaticContact CE2-CE1 3.73Å; W81-F424 AromaticContact CE2-CZ 3.48Å; W81-F424 VanDerWaalsContact CE2-CZ 3.48Å; W81-F424 HydrophobicContact CE3-CZ 4.39Å; W81-F424 HydrophobicContact CH2-CE1 4.13Å; W81-F424 HydrophobicContact CH2-CZ 4.01Å; W81-F424 AromaticContact CZ2-CE1 3.45Å; W81-F424 HydrophobicContact CZ2-CE1 3.45Å; W81-F424 VanDerWaalsContact CZ2-CE1 3.45Å; W81-F424 AromaticContact CZ2-CZ 3.54Å; W81-F424 HydrophobicContact CZ2-CZ 3.54Å; W81-F424 HydrophobicContact CZ3-CZ 4.4Å; W81-F424 AromaticContact NE1-CE1 3.9Å; W81-F424 AromaticContact NE1-CZ 3.75Å; I89-F424 HydrophobicContact CD1-CE2 3.79Å; I89-F424 HydrophobicContact CD1-CZ 3.97Å; V415-F424 HydrophobicContact CG1-CD2 3.69Å; V415-F424 HydrophobicContact CG1-CE2 4.31Å; V415-F424 HydrophobicContact CG1-CG 4.45Å; S416-F424 CarbonylContact O-C 3.58Å; S416-F424 WeakPolarHBondContact O-CA 3.49Å; S416-F424 WeakPolarHBondContact O-CB 3.44Å; F424-L426 HydrophobicContact CD2-CD2 4.15Å; F424-L426 HydrophobicContact CE2-CD2 4.02Å
425Y97.9Very high89.3Confident8 Ų843.8 Ų43.83%0.03123%0.231CC..EExtended strand (participates in β ladder)trans-124.7138.3-165.9-56.3-89.3000110.1Y48 F367 V415 S416 A418 K421 R423Y48-Y425 AromaticContact CD1-CD1 3.66Å; Y48-Y425 HydrophobicContact CD1-CD1 3.66Å; Y48-Y425 HydrophobicContact CD1-CE1 4.32Å; Y48-Y425 HydrophobicContact CD1-CG 4.43Å; Y48-Y425 AromaticContact CD2-CD1 3.8Å; Y48-Y425 HydrophobicContact CD2-CD1 3.8Å; Y48-Y425 AromaticContact CE1-CD1 3.68Å; Y48-Y425 HydrophobicContact CE1-CD1 3.68Å; Y48-Y425 AromaticContact CE1-CE1 3.88Å; Y48-Y425 HydrophobicContact CE1-CE1 3.88Å; Y48-Y425 AromaticContact CE2-CD1 3.82Å; Y48-Y425 HydrophobicContact CE2-CD1 3.82Å; Y48-Y425 HydrophobicContact CE2-CE1 4.22Å; Y48-Y425 AromaticContact CG-CD1 3.74Å; Y48-Y425 HydrophobicContact CG-CD1 3.74Å; Y48-Y425 HydrophobicContact CG-CG 4.41Å; Y48-Y425 AromaticContact CZ-CD1 3.78Å; Y48-Y425 AromaticContact CZ-CE1 3.86Å; F367-Y425 HydrophobicContact CD1-CD2 4.19Å; F367-Y425 HydrophobicContact CE1-CD1 4.44Å; F367-Y425 AromaticContact CE1-CD2 3.76Å; F367-Y425 HydrophobicContact CE1-CD2 3.76Å; F367-Y425 HydrophobicContact CE1-CE2 4.37Å; F367-Y425 AromaticContact CE1-CG 3.82Å; F367-Y425 HydrophobicContact CE1-CG 3.82Å; V415-Y425 CarbonylContact C-O 3.22Å; V415-Y425 WeakPolarHBondContact CA-O 3.11Å; S416-Y425 PolarHBondContact N-O 3.4Å; S416-Y425 WeakPolarHBondContact O-CD2 3.49Å; S416-Y425 PolarHBondContact O-N 3.29Å; A418-Y425 HydrophobicContact CB-CD2 4.2Å; A418-Y425 HydrophobicContact CB-CE2 3.54Å; K421-Y425 HydrophobicContact CB-CE2 4.35Å; K421-Y425 WeakPolarHBondContact CG-OH 3.41Å; R423-Y425 HydrophobicContact CB-CE2 4.36Å; R423-Y425 WeakPolarHBondContact O-CE2 3.44Å
426L97Very high86.7Confident5 Ų548.1 Ų48.13%0.02627%0.266CS..EExtended strand (participates in β ladder)trans-107.4120.9177.8-55.9-172.4000110.1Y48 E49 K50 F52 I89 M413 I414 V415 F424Y48-L426 CarbonylContact C-O 3.59Å; Y48-L426 WeakPolarHBondContact CA-O 3.4Å; Y48-L426 WeakPolarHBondContact CB-O 3.46Å; E49-L426 PolarHBondContact N-O 3.49Å; K50-L426 HydrophobicContact CB-CD1 4.4Å; K50-L426 PolarHBondContact O-N 3.42Å; F52-L426 HydrophobicContact CD2-CD1 4.29Å; F52-L426 HydrophobicContact CD2-CG 4.5Å; F52-L426 HydrophobicContact CE2-CD1 3.66Å; F52-L426 HydrophobicContact CE2-CG 4.3Å; I89-L426 HydrophobicContact CD1-CD1 3.84Å; I89-L426 HydrophobicContact CD1-CD2 4.34Å; I89-L426 HydrophobicContact CG1-CD1 3.91Å; I89-L426 HydrophobicContact CG2-CD1 4.07Å; M413-L426 HydrophobicContact SD-CD1 4.46Å; M413-L426 HydrophobicContact SD-CD2 4.23Å; I414-L426 WeakPolarHBondContact O-CA 3.32Å; V415-L426 HydrophobicContact CB-CD2 4.33Å; V415-L426 HydrophobicContact CG1-CD2 4.14Å; V415-L426 HydrophobicContact CG2-CD2 3.77Å; F424-L426 HydrophobicContact CD2-CD2 4.15Å; F424-L426 HydrophobicContact CE2-CD2 4.02Å
427F97.1Very high84.2Confident0 Ų051.5 Ų51.50%029%0.288CS..EExtended strand (participates in β ladder)trans-102.6128.7168.7-69.3-88.9000109.3P43 I345 L359 F367 M413 I414P43-F427 HydrophobicContact CB-CB 4.2Å; P43-F427 HydrophobicContact CG-CB 4.45Å; P43-F427 VanDerWaalsContact CG-O 3.28Å; P43-F427 WeakPolarHBondContact CG-O 3.41Å; I345-F427 HydrophobicContact CD1-CD2 3.93Å; I345-F427 HydrophobicContact CD1-CE2 3.61Å; I345-F427 HydrophobicContact CD1-CZ 4.25Å; L359-F427 HydrophobicContact CB-CD1 3.85Å; L359-F427 HydrophobicContact CB-CE1 4.02Å; L359-F427 HydrophobicContact CB-CG 4.39Å; L359-F427 HydrophobicContact CD1-CB 4.27Å; L359-F427 HydrophobicContact CD1-CG 4.47Å; F367-F427 HydrophobicContact CD1-CE2 4.35Å; F367-F427 HydrophobicContact CD2-CZ 4.48Å; F367-F427 AromaticContact CE1-CE2 3.87Å; F367-F427 HydrophobicContact CE1-CE2 3.87Å; F367-F427 AromaticContact CE1-CZ 3.97Å; F367-F427 HydrophobicContact CE1-CZ 3.97Å; F367-F427 HydrophobicContact CE2-CE2 4.25Å; F367-F427 AromaticContact CE2-CZ 3.72Å; F367-F427 HydrophobicContact CE2-CZ 3.72Å; F367-F427 AromaticContact CZ-CE2 3.83Å; F367-F427 HydrophobicContact CZ-CE2 3.83Å; F367-F427 AromaticContact CZ-CZ 3.43Å; F367-F427 HydrophobicContact CZ-CZ 3.43Å; F367-F427 VanDerWaalsContact CZ-CZ 3.43Å; M413-F427 CarbonylContact C-O 3.55Å; M413-F427 VanDerWaalsContact CA-O 3.29Å; M413-F427 WeakPolarHBondContact CA-O 3.48Å; I414-F427 HydrophobicContact CB-CB 4.24Å; I414-F427 PolarHBondContact N-O 3.03Å; I414-F427 PolarHBondContact O-N 3.07Å
428T95Very high81.7Confident4 Ų460.3 Ų60.33%0.02533%0.328CS..  trans-133.7-162.5179.467.80000109.1P43 S44 A45 E49 M413 S430P43-T428 WeakPolarHBondContact CB-O 3.38Å; S44-T428 PolarHBondContact N-O 3.37Å; A45-T428 WeakPolarHBondContact CB-O 3.46Å; A45-T428 PolarHBondContact N-O 3.43Å; A45-T428 VanDerWaalsContact N-O 3.08Å; E49-T428 WeakPolarHBondContact OE2-CB 3.41Å; E49-T428 WeakPolarHBondContact OE2-CG2 3.34Å; E49-T428 PolarHBondContact OE2-OG1 3.36Å; M413-T428 HydrophobicContact CB-CG2 4.5Å; M413-T428 HydrophobicContact CE-CG2 4.15Å; M413-T428 HydrophobicContact CG-CG2 4.26Å; T428-S430 VanDerWaalsContact C-N 3.3Å; T428-S430 PolarHBondContact OG1-N 3.03Å; T428-S430 VanDerWaalsContact OG1-N 3.07Å
429N91.5Very high79.4Confident75 Ų7567.4 Ų67.440%0.40137%0.366SS..SBendtrans-84.1-6.5169.6-68.3-24.2000113.1S44 P412S44-N429 PolarHBondContact N-OD1 3.46Å; S44-N429 VanDerWaalsContact N-OD1 3.09Å; S44-N429 PolarHBondContact OG-OD1 3.32Å; S44-N429 VanDerWaalsContact OG-OD1 3.1Å; P412-N429 WeakPolarHBondContact CD-ND2 3.31Å; P412-N429 WeakPolarHBondContact CG-ND2 3.21Å
430S88Confident77.4Confident64 Ų6469.3 Ų69.345%0.44838%0.377SS..SBendtrans-96.4126.3-177.6-61.20000110.6A45 T428A45-S430 WeakPolarHBondContact CB-O 3.43Å; T428-S430 VanDerWaalsContact C-N 3.3Å; T428-S430 PolarHBondContact OG1-N 3.03Å; T428-S430 VanDerWaalsContact OG1-N 3.07Å
431E86.2Confident76.2Confident86 Ų8668.2 Ų68.240%0.40237%0.374SS..PPolyproline II helixtrans-70.7149.6165.6-64.6-70.8-17400109.6A45 N46 A47A45-E431 HydrophobicContact CB-CG 4.44Å; N46-E431 WeakPolarHBondContact CB-OE1 3.32Å; N46-E431 PolarHBondContact N-OE1 3.07Å; N46-E431 PolarHBondContact N-OE2 2.68Å; N46-E431 PolarHBondContact ND2-OE1 3.42Å; A47-E431 WeakPolarHBondContact CB-OE2 3.5Å; A47-E431 PolarHBondContact N-OE2 2.73Å; A47-E431 VanDerWaalsContact N-OE2 3.08Å
432P81.6Confident75.7Confident27 Ų2767.1 Ų67.118%0.17537%0.368CS..PPolyproline II helixtrans-63.8146.4-179.927.6-35.6000111.6A47 T434 R442A47-P432 HydrophobicContact CB-CG 3.86Å; P432-T434 PolarHBondContact O-N 3.15Å; P432-R442 HydrophobicContact CB-CG 3.88Å
433F67.4Low75.5Confident120 Ų12067.5 Ų67.553%0.52637%0.369SS..PPolyproline II helixtrans-62.7132.1173.3-66.5-79.2000110.7N440F433-N440 HydrophobicContact CB-CB 4.15Å; F433-N440 HydrophobicContact CD2-CB 3.99Å; F433-N440 HydrophobicContact CG-CB 4.13Å
434T56.3Low75.1Confident149 Ų14967.8 Ų67.891%0.91438%0.375SS*.SBendtrans-80.4-23.3179.750.30000113.1P432P432-T434 PolarHBondContact O-N 3.15Å
435S48.7Very low74.4Confident78 Ų7873.3 Ų73.355%0.54540%0.404SS..SBendtrans-105.3108.517840.30000110.6T437S435-T437 VanDerWaalsContact C-N 3.34Å; S435-T437 PolarHBondContact O-N 2.8Å
436A43.3Very low73.8Confident90 Ų9075.6 Ų75.674%0.74442%0.416SS*.  trans-67.489.6172.100000110
437T46.3Very low73Confident72 Ų7276.6 Ų76.644%0.44242%0.421SS..  trans-80.4154.2153.450.10000108.2S435 D439 N440S435-T437 VanDerWaalsContact C-N 3.34Å; S435-T437 PolarHBondContact O-N 2.8Å; T437-D439 PolarHBondContact O-N 2.98Å; T437-N440 PolarHBondContact O-N 3.38Å; T437-N440 WeakPolarHBondContact OG1-CB 3.46Å; T437-N440 PolarHBondContact OG1-ND2 3.38Å
438Q46.2Very low71.7Confident185 Ų18585.3 Ų85.386%0.86446%0.459SS*.THydrogen-bonded Turntrans-49-31.3-178.5-91.2178.7-19.900113.9
439D47.8Very low70.1Confident150 Ų15088.9 Ų88.980%0.80248%0.482SS*.THydrogen-bonded Turntrans-88.3-10.3179.4-64-36.3000115T437T437-D439 PolarHBondContact O-N 2.98Å
440N55.3Low68.4Low53 Ų5390.4 Ų90.428%0.28348%0.482SS..  trans-116.732.5-173-71.1-33.2000112.9F433 T437 R442F433-N440 HydrophobicContact CB-CB 4.15Å; F433-N440 HydrophobicContact CD2-CB 3.99Å; F433-N440 HydrophobicContact CG-CB 4.13Å; T437-N440 PolarHBondContact O-N 3.38Å; T437-N440 WeakPolarHBondContact OG1-CB 3.46Å; T437-N440 PolarHBondContact OG1-ND2 3.38Å; N440-R442 PolarHBondContact O-N 3.04Å
441E70.8Confident66.7Low92 Ų9295.1 Ų95.143%0.4350%0.497SS..  trans-69.6114.9174.2-70.3-172171.800110.9D443E441-D443 VanDerWaalsContact C-N 3.26Å; E441-D443 PolarHBondContact O-N 3.11Å
442R85.6Confident65.2Low63 Ų6396.7 Ų96.724%0.23851%0.505CS..SBendtrans-54.1-43.2172.4-172.7-170.9-171.8-163.9-2.2112Y48 E49 K50 S51 E363 P432 N440Y48-R442 HydrophobicContact CD2-CG 4.33Å; Y48-R442 HydrophobicContact CE2-CG 3.84Å; Y48-R442 VanDerWaalsContact CE2-CZ 3.44Å; Y48-R442 VanDerWaalsContact CG-NH2 3.34Å; Y48-R442 VanDerWaalsContact CZ-NH2 3.25Å; Y48-R442 PolarHBondContact O-NE 3.05Å; Y48-R442 PolarHBondContact O-NH2 3.13Å; E49-R442 WeakPolarHBondContact O-CG 3.38Å; K50-R442 CarbonylContact C-O 3.49Å; K50-R442 WeakPolarHBondContact CA-O 3.32Å; S51-R442 PolarHBondContact N-O 3.2Å; E363-R442 IonicContact OE1-CZ 3.92Å; E363-R442 IonicContact OE1-NH1 3.49Å; E363-R442 IonicContact OE1-NH2 2.78Å; E363-R442 PolarHBondContact OE1-NH2 3.39Å; E363-R442 IonicContact OE2-NH1 2.63Å; E363-R442 IonicContact OE2-NH2 3.14Å; P432-R442 HydrophobicContact CB-CG 3.88Å; N440-R442 PolarHBondContact O-N 3.04Å
443D89.6Confident63.9Low62 Ų6299.1 Ų99.133%0.33252%0.516SS..BIsolated β-bridgetrans-106.281.1-175.2-69.7-49.2000111.6Y48 S51 E441 L445Y48-D443 PolarHBondContact OH-OD1 2.85Å; S51-D443 WeakPolarHBondContact CB-OD1 3.44Å; S51-D443 PolarHBondContact OG-OD1 3.15Å; E441-D443 VanDerWaalsContact C-N 3.26Å; E441-D443 PolarHBondContact O-N 3.11Å; D443-L445 PolarHBondContact O-N 2.88Å
444V87.3Confident63.1Low40 Ų4098 Ų9824%0.24252%0.515CS..  trans-59.3131.8-174.4-175.20000111.4S51 F52 R423 N446S51-V444 WeakPolarHBondContact O-CB 3.36Å; S51-V444 PolarHBondContact O-N 3.23Å; F52-V444 HydrophobicContact CD1-CB 3.93Å; F52-V444 HydrophobicContact CD1-CG1 4.04Å; F52-V444 HydrophobicContact CD1-CG2 4.35Å; F52-V444 HydrophobicContact CE1-CB 3.98Å; F52-V444 HydrophobicContact CE1-CG1 3.95Å; F52-V444 HydrophobicContact CE1-CG2 3.96Å; F52-V444 HydrophobicContact CZ-CG2 4.12Å; R423-V444 PolarHBondContact NH1-O 3.33Å; V444-N446 HydrophobicContact CG1-CB 4.33Å; V444-N446 PolarHBondContact O-N 3.47Å
445L83.5Confident62.9Low116 Ų11696.6 Ų96.661%0.60750%0.501SS*.  trans-95.472.1175.2-65.6175.5000111M53 D443M53-L445 HydrophobicContact SD-CD2 3.58Å; M53-L445 VanDerWaalsContact SD-CD2 3.58Å; D443-L445 PolarHBondContact O-N 2.88Å
446N85.8Confident63Low56 Ų5696.3 Ų96.330%0.29950%0.496SS..  trans-85.9-4-179.964.6-72.6000114.3M53 V444M53-N446 PolarHBondContact N-OD1 2.91Å; M53-N446 PolarHBondContact O-ND2 3.2Å; V444-N446 HydrophobicContact CG1-CB 4.33Å; V444-N446 PolarHBondContact O-N 3.47Å
447E80.3Confident63Low26 Ų2696.1 Ų96.112%0.12149%0.49CS..SBendtrans-111.4146.1175.3-76.1-68.8160.600110M53 R55 K79M53-E447 HydrophobicContact CB-CB 4.1Å; M53-E447 HydrophobicContact CB-CG 3.98Å; R55-E447 HydrophobicContact CG-CG 4.41Å; R55-E447 WeakPolarHBondContact CG-OE2 3.16Å; R55-E447 IonicContact NE-OE2 2.91Å; R55-E447 PolarHBondContact NE-OE2 3.07Å; K79-E447 WeakPolarHBondContact CE-OE1 3.35Å; K79-E447 IonicContact NZ-OE1 3.76Å; K79-E447 PolarHBondContact NZ-OE1 2.95Å
448K70.2Confident62.5Low184 Ų18498.8 Ų98.880%0.850%0.5SS*.PPolyproline II helixtrans-69.9129.4169.9-67.5-175.8-179.7-178.20108.3
449P59.6Low62.1Low79 Ų7995.6 Ų95.651%0.51350%0.495SS..PPolyproline II helixtrans-52.3146.1175.9-25.433.2000111.3D453 L454P449-D453 HydrophobicContact CB-CB 4.34Å; P449-L454 HydrophobicContact CB-CD1 4.25Å; P449-L454 HydrophobicContact CB-CG 4.02Å
450R56.9Low61.3Low106 Ų10697.4 Ų97.440%0.450%0.499SS..PPolyproline II helixtrans-61.2147.9172.9-61.7-179177-168.5-1.2107.9R55 D56 E452 D453 L454R55-R450 PolarHBondContact O-NE 2.81Å; R55-R450 PolarHBondContact O-NH2 3.42Å; D56-R450 IonicContact OD2-NH2 3.79Å; D56-R450 PolarHBondContact OD2-NH2 3.36Å; R450-E452 HydrophobicContact CB-CB 4.45Å; R450-E452 PolarHBondContact O-N 3.05Å; R450-E452 VanDerWaalsContact O-N 3.12Å; R450-D453 HydrophobicContact CB-CB 4.4Å; R450-D453 VanDerWaalsContact CB-OD2 3.3Å; R450-D453 WeakPolarHBondContact CB-OD2 3.5Å; R450-D453 PolarHBondContact N-OD2 2.85Å; R450-D453 WeakPolarHBondContact O-CA 3.34Å; R450-D453 WeakPolarHBondContact O-CB 3.24Å; R450-D453 PolarHBondContact O-N 2.64Å; R450-L454 PolarHBondContact O-N 2.72Å
451Q52.3Low60Low163 Ų163102.5 Ų102.576%0.76252%0.521SS*.Hα-helixtrans-57.5-28.6174.8-168.2166.11.700111.4L455Q451-L455 WeakPolarHBondContact O-CD1 3.37Å; Q451-L455 WeakPolarHBondContact O-CG 3.2Å; Q451-L455 PolarHBondContact O-N 3.27Å
452E54.5Low58.4Low119 Ų119103.9 Ų103.956%0.55654%0.538SS*.Hα-helixtrans-66.5-37.5171.4-65.3172.617600113.3R450 L455R450-E452 HydrophobicContact CB-CB 4.45Å; R450-E452 PolarHBondContact O-N 3.05Å; R450-E452 VanDerWaalsContact O-N 3.12Å; E452-L455 PolarHBondContact O-N 2.63Å
453D53.6Low55.8Low79 Ų79106.6 Ų106.642%0.42256%0.562SS.*Hα-helixtrans-73.7-34.9177-59.9-36.4000111.6P449 R450 L455 T456 S457P449-D453 HydrophobicContact CB-CB 4.34Å; R450-D453 HydrophobicContact CB-CB 4.4Å; R450-D453 VanDerWaalsContact CB-OD2 3.3Å; R450-D453 WeakPolarHBondContact CB-OD2 3.5Å; R450-D453 PolarHBondContact N-OD2 2.85Å; R450-D453 WeakPolarHBondContact O-CA 3.34Å; R450-D453 WeakPolarHBondContact O-CB 3.24Å; R450-D453 PolarHBondContact O-N 2.64Å; D453-L455 PolarHBondContact O-N 3.1Å; D453-T456 VanDerWaalsContact C-OG1 3.31Å; D453-T456 WeakPolarHBondContact CA-OG1 3.47Å; D453-T456 PolarHBondContact O-N 2.93Å; D453-T456 PolarHBondContact O-OG1 2.93Å; D453-S457 PolarHBondContact O-N 3.27Å
454L50.7Low53.3Low96 Ų96111.6 Ų111.650%0.50358%0.581SS.*Hα-helixtrans-63.8-31173.7-81.6152.4000112.2P449 R450 T456 S457P449-L454 HydrophobicContact CB-CD1 4.25Å; P449-L454 HydrophobicContact CB-CG 4.02Å; R450-L454 PolarHBondContact O-N 2.72Å; L454-T456 PolarHBondContact O-N 2.81Å; L454-S457 PolarHBondContact O-OG 3.38Å
455L52.8Low51.2Low119 Ų119116 Ų11662%0.62360%0.597SS**THydrogen-bonded Turntrans-72.2-15.8174.3-73.8159.4000112.7Q451 E452 D453Q451-L455 WeakPolarHBondContact O-CD1 3.37Å; Q451-L455 WeakPolarHBondContact O-CG 3.2Å; Q451-L455 PolarHBondContact O-N 3.27Å; E452-L455 PolarHBondContact O-N 2.63Å; D453-L455 PolarHBondContact O-N 3.1Å
456T51Low49.8Very low72 Ų72119.3 Ų119.344%0.44261%0.609SS.*THydrogen-bonded Turntrans-94.6-16.4177.734.30000115.8D453 L454D453-T456 VanDerWaalsContact C-OG1 3.31Å; D453-T456 WeakPolarHBondContact CA-OG1 3.47Å; D453-T456 PolarHBondContact O-N 2.93Å; D453-T456 PolarHBondContact O-OG1 2.93Å; L454-T456 PolarHBondContact O-N 2.81Å
457S42.6Very low49.1Very low87 Ų87119.9 Ų119.961%0.60861%0.611SS**  trans-933.7-17355.20000114.9D453 L454D453-S457 PolarHBondContact O-N 3.27Å; L454-S457 PolarHBondContact O-OG 3.38Å
458I37.3Very low49.2Very low127 Ų127120.4 Ų120.465%0.65162%0.615SS**SBendtrans-78.5121.1167.3-58.1176.1000107.1E460I458-E460 PolarHBondContact O-N 3.19Å
459P36.7Very low50.2Low118 Ų118116.3 Ų116.377%0.76660%0.599SS**  trans-55.4130.6-175.818.9-29.2000111E461P459-E461 PolarHBondContact O-N 2.83Å
460E30.9Very low51.8Low188 Ų188114.2 Ų114.288%0.87959%0.585SS**  trans-6094.3-168.7-60.4177.4163.200112.3I458I458-E460 PolarHBondContact O-N 3.19Å
461E27.8Very low53.6Low161 Ų161109.2 Ų109.275%0.75257%0.567SS**  trans-85.5132.1133.3-79.1-168165.100106.9P459 T463P459-E461 PolarHBondContact O-N 2.83Å; E461-T463 PolarHBondContact O-N 2.76Å; E461-T463 PolarHBondContact O-OG1 2.74Å
462P36.9Very low55.7Low120 Ų120101.9 Ų101.978%0.77953%0.533SS*.  trans-72.577.8-165.131.2-34.9000109.9
463T32.1Very low57.8Low120 Ų12096.3 Ų96.374%0.73651%0.507SS*.  trans-101100.5175.146.80000105.5E461 K465E461-T463 PolarHBondContact O-N 2.76Å; E461-T463 PolarHBondContact O-OG1 2.74Å; T463-K465 PolarHBondContact O-N 2.79Å
464F37Very low59.9Low168 Ų16894.8 Ų94.874%0.73750%0.497SS*.  trans-38.1103.8173.3-73.2-97.6000109.5H466 L467F464-H466 PolarHBondContact O-N 2.85Å; F464-L467 HydrophobicContact CD1-CD1 4.49Å
465K42.6Very low62.1Low132 Ų13290.7 Ų90.757%0.57448%0.476SS*.  trans-43.2120.6171-76.1-178.5177.3179.40107.1T463 L467T463-K465 PolarHBondContact O-N 2.79Å; K465-L467 VanDerWaalsContact C-N 3.34Å; K465-L467 PolarHBondContact O-N 2.85Å
466H54.8Low64.1Low185 Ų18588.7 Ų88.786%0.85647%0.469SS*.  trans-35.893.9-175.4-81.2-83.4000112F464 I468F464-H466 PolarHBondContact O-N 2.85Å; H466-I468 PolarHBondContact O-N 3.28Å
467L70.8Confident66.1Low68 Ų6889.2 Ų89.236%0.35647%0.468SS..  trans-69.3123.6178.7-70.7168.6000105.9F464 K465 E469 P486 K487F464-L467 HydrophobicContact CD1-CD1 4.49Å; K465-L467 VanDerWaalsContact C-N 3.34Å; K465-L467 PolarHBondContact O-N 2.85Å; L467-E469 HydrophobicContact CB-CG 4.34Å; L467-E469 PolarHBondContact O-N 3.48Å; L467-P486 HydrophobicContact CB-CB 3.95Å; L467-P486 HydrophobicContact CB-CG 3.64Å; L467-P486 HydrophobicContact CD1-CB 4.42Å; L467-P486 HydrophobicContact CD1-CG 4.26Å; L467-P486 HydrophobicContact CD2-CB 3.78Å; L467-P486 HydrophobicContact CD2-CG 4.38Å; L467-P486 HydrophobicContact CG-CB 4.24Å; L467-P486 HydrophobicContact CG-CG 4.29Å; L467-K487 HydrophobicContact CD1-CG 3.89Å
468I82.4Confident68.7Low38 Ų3886.4 Ų86.420%0.19545%0.452CS..  trans-70.799.8174.9-61.6178.6000106.9H466 S470 L484 T497 F622H466-I468 PolarHBondContact O-N 3.28Å; I468-S470 WeakPolarHBondContact CG2-O 3.31Å; I468-L484 HydrophobicContact CG2-CD1 4.1Å; I468-T497 HydrophobicContact CB-CG2 4.12Å; I468-T497 HydrophobicContact CD1-CG2 4.21Å; I468-T497 HydrophobicContact CG2-CG2 3.94Å; I468-F622 HydrophobicContact CD1-CD1 4.35Å; I468-F622 HydrophobicContact CD1-CG 4.46Å; I468-F622 HydrophobicContact CG2-CD1 3.29Å; I468-F622 HydrophobicContact CG2-CE1 3.73Å; I468-F622 HydrophobicContact CG2-CG 4.13Å
469E90.3Very high71.5Confident98 Ų9883.5 Ų83.546%0.45844%0.438SS..  trans-93.3-6.3-177.4-69.2-176.5173.900113.1L467 K483 L484 P486L467-E469 HydrophobicContact CB-CG 4.34Å; L467-E469 PolarHBondContact O-N 3.48Å; E469-K483 CarbonylContact O-C 3.59Å; E469-K483 WeakPolarHBondContact O-CA 3.48Å; E469-L484 PolarHBondContact O-N 3.4Å; E469-P486 HydrophobicContact CG-CG 3.9Å
470S93.8Very high74.4Confident34 Ų3477.9 Ų77.924%0.23840%0.402CS..EExtended strand (participates in β ladder)trans-150.8155.5177.467.70000113I468 C482I468-S470 WeakPolarHBondContact CG2-O 3.31Å; S470-C482 CarbonylContact C-O 3.54Å; S470-C482 WeakPolarHBondContact CA-O 3.14Å; S470-C482 WeakPolarHBondContact CB-O 3.25Å
471C95.4Very high77.6Confident1 Ų171 Ų711%0.00737%0.369CS..EExtended strand (participates in β ladder)trans-146.1164.8171.971.10000111.4C482 L484 I620 S621 F622C471-C482 PolarHBondContact N-O 2.81Å; C471-C482 PolarHBondContact O-N 3.13Å; C471-L484 HydrophobicContact CB-CD1 4.38Å; C471-I620 HydrophobicContact CB-CG2 4.07Å; C471-S621 CarbonylContact C-O 3.54Å; C471-S621 WeakPolarHBondContact CA-O 3.43Å; C471-S621 WeakPolarHBondContact CB-O 3.26Å; C471-F622 HydrophobicContact CB-CD1 3.63Å; C471-F622 HydrophobicContact CB-CE1 3.53Å
472V96.7Very high80.9Confident10 Ų1063.3 Ų63.36%0.06133%0.333CS..EExtended strand (participates in β ladder)trans-121.6119.6170.3-168.80000108.4D479 I480 H481 I620 S621 P623V472-D479 HydrophobicContact CG1-CB 3.9Å; V472-I480 CarbonylContact C-O 3.59Å; V472-I480 WeakPolarHBondContact CA-O 3.36Å; V472-H481 VanDerWaalsContact CG2-ND1 3.3Å; V472-H481 WeakPolarHBondContact CG2-ND1 3.48Å; V472-I620 CarbonylContact O-C 3.58Å; V472-I620 VanDerWaalsContact O-CA 3.32Å; V472-I620 WeakPolarHBondContact O-CA 3.35Å; V472-S621 PolarHBondContact N-O 3.29Å; V472-S621 PolarHBondContact O-N 2.87Å; V472-P623 HydrophobicContact CG2-CG 4.11Å
473I98Very high83.8Confident2 Ų262.8 Ų62.81%0.0132%0.319CS..EExtended strand (participates in β ladder)trans-90.9107.6173.7-53.1174.3000106.9T475 I480 F496 M555 F569 I617 I620I473-T475 HydrophobicContact CG2-CG2 3.94Å; I473-I480 HydrophobicContact CB-CB 4.29Å; I473-I480 PolarHBondContact N-O 3.27Å; I473-I480 PolarHBondContact O-N 2.79Å; I473-F496 HydrophobicContact CD1-CZ 4.47Å; I473-M555 HydrophobicContact CD1-CE 4.12Å; I473-F569 HydrophobicContact CD1-CE2 4.29Å; I473-F569 HydrophobicContact CD1-CZ 4.19Å; I473-I617 HydrophobicContact CG2-CD1 4.11Å; I473-I617 HydrophobicContact CG2-CG1 3.93Å; I473-I617 HydrophobicContact CG2-CG2 4.09Å; I473-I620 HydrophobicContact CB-CG1 4.47Å; I473-I620 HydrophobicContact CG1-CD1 4.29Å; I473-I620 HydrophobicContact CG1-CG1 4.26Å; I473-I620 HydrophobicContact CG2-CG1 4.22Å
474H96.8Very high86.8Confident46 Ų4657.2 Ų57.221%0.21328%0.284CS..EExtended strand (participates in β ladder)trans-81.2117.2174.6-59-68.9000108.5D479 I617 V618 S619 S621H474-D479 IonicContact CE1-OD1 2.9Å; H474-D479 IonicContact CE1-OD2 3.61Å; H474-D479 IonicContact CG-OD1 3.72Å; H474-D479 IonicContact ND1-OD1 3.62Å; H474-D479 PolarHBondContact ND1-OD1 2.77Å; H474-D479 IonicContact ND1-OD2 2.71Å; H474-D479 PolarHBondContact ND1-OD2 2.81Å; H474-I617 CarbonylContact O-C 3.4Å; H474-V618 HydrophobicContact CB-CB 4.37Å; H474-V618 PolarHBondContact O-N 3.31Å; H474-S619 WeakPolarHBondContact CB-O 3.47Å; H474-S619 PolarHBondContact CD2-OG 3.2Å; H474-S619 PolarHBondContact N-O 2.78Å; H474-S619 PolarHBondContact O-N 2.8Å; H474-S621 PolarHBondContact NE2-OG 3.22Å
475T97.2Very high89.6Confident10 Ų1050.8 Ų50.86%0.06126%0.256CS..EExtended strand (participates in β ladder)trans-115.1162.9177.978.80000110.7I473 M477 G478 I480 F510 I599 S616I473-T475 HydrophobicContact CG2-CG2 3.94Å; T475-M477 PolarHBondContact O-N 3.05Å; T475-M477 VanDerWaalsContact O-N 3.09Å; T475-M477 PolarHBondContact OG1-N 2.79Å; T475-M477 VanDerWaalsContact OG1-N 3.15Å; T475-G478 WeakPolarHBondContact CA-O 3.33Å; T475-G478 WeakPolarHBondContact CB-O 3.32Å; T475-G478 PolarHBondContact N-O 2.94Å; T475-G478 PolarHBondContact O-N 2.9Å; T475-G478 PolarHBondContact OG1-N 2.6Å; T475-G478 PolarHBondContact OG1-O 2.72Å; T475-I480 HydrophobicContact CG2-CD1 3.96Å; T475-F510 HydrophobicContact CG2-CE2 3.91Å; T475-F510 HydrophobicContact CG2-CZ 4.07Å; T475-I599 HydrophobicContact CG2-CD1 4.49Å; T475-S616 WeakPolarHBondContact CA-O 3.49Å
476T94.1Very high91.9Very high77 Ų7745 Ų4547%0.47223%0.231SC..THydrogen-bonded Turntrans-58.3-15.8170.244.70000114.2I615 S616 V618T476-I615 WeakPolarHBondContact OG1-CG2 2.93Å; T476-S616 WeakPolarHBondContact CG2-OG 3.15Å; T476-S616 PolarHBondContact N-O 2.8Å; T476-S616 PolarHBondContact OG1-N 2.67Å; T476-S616 VanDerWaalsContact OG1-N 3.1Å; T476-S616 PolarHBondContact OG1-O 3Å; T476-V618 HydrophobicContact CG2-CG2 4.18Å
477M94.5Very high93.4Very high84 Ų8442.7 Ų42.741%0.41422%0.219SC..THydrogen-bonded Turntrans-106.34.5175.8-64.3-16292.100114.1T475 V595 N598 I599 V602 I615T475-M477 PolarHBondContact O-N 3.05Å; T475-M477 VanDerWaalsContact O-N 3.09Å; T475-M477 PolarHBondContact OG1-N 2.79Å; T475-M477 VanDerWaalsContact OG1-N 3.15Å; M477-V595 HydrophobicContact CB-CG1 4.25Å; M477-N598 HydrophobicContact CE-CB 4.48Å; M477-I599 HydrophobicContact CB-CG1 4.17Å; M477-I599 HydrophobicContact CG-CG1 4.32Å; M477-I599 HydrophobicContact SD-CG1 3.77Å; M477-V602 HydrophobicContact CE-CG1 4.4Å; M477-V602 HydrophobicContact SD-CG1 4.17Å; M477-I615 HydrophobicContact CG-CG1 4.32Å; M477-I615 HydrophobicContact CG-CG2 3.99Å; M477-I615 HydrophobicContact SD-CD1 3.65Å; M477-I615 HydrophobicContact SD-CG1 3.99Å; M477-I615 HydrophobicContact SD-CG2 4.36Å
478G96.1Very high94.4Very high27 Ų2742.7 Ų42.728%0.27822%0.217SC..EExtended strand (participates in β ladder)trans123.7-173.3-178.600000113.6T475T475-G478 WeakPolarHBondContact CA-O 3.33Å; T475-G478 WeakPolarHBondContact CB-O 3.32Å; T475-G478 PolarHBondContact N-O 2.94Å; T475-G478 PolarHBondContact O-N 2.9Å; T475-G478 PolarHBondContact OG1-N 2.6Å; T475-G478 PolarHBondContact OG1-O 2.72Å
479D97.1Very high94.8Very high67 Ų6740.9 Ų40.936%0.35821%0.208SC..EExtended strand (participates in β ladder)trans-97.7137.5-171.8-69.3-9.2000112.4V472 H474 G592V472-D479 HydrophobicContact CG1-CB 3.9Å; H474-D479 IonicContact CE1-OD1 2.9Å; H474-D479 IonicContact CE1-OD2 3.61Å; H474-D479 IonicContact CG-OD1 3.72Å; H474-D479 IonicContact ND1-OD1 3.62Å; H474-D479 PolarHBondContact ND1-OD1 2.77Å; H474-D479 IonicContact ND1-OD2 2.71Å; H474-D479 PolarHBondContact ND1-OD2 2.81Å; D479-G592 WeakPolarHBondContact O-CA 3.4Å
480I98Very high94.9Very high0 Ų039.4 Ų39.40%021%0.207CC..EExtended strand (participates in β ladder)trans-116.9114.5174.9-55.4168.2000107.9V472 I473 T475 I571 V589 V595 V596 I599V472-I480 CarbonylContact C-O 3.59Å; V472-I480 WeakPolarHBondContact CA-O 3.36Å; I473-I480 HydrophobicContact CB-CB 4.29Å; I473-I480 PolarHBondContact N-O 3.27Å; I473-I480 PolarHBondContact O-N 2.79Å; T475-I480 HydrophobicContact CG2-CD1 3.96Å; I480-I571 HydrophobicContact CG2-CD1 4.42Å; I480-V589 HydrophobicContact CG2-CB 4.19Å; I480-V589 HydrophobicContact CG2-CG1 3.5Å; I480-V589 HydrophobicContact CG2-CG2 3.61Å; I480-V595 HydrophobicContact CD1-CG1 4.25Å; I480-V595 HydrophobicContact CG1-CB 4.09Å; I480-V595 HydrophobicContact CG1-CG1 3.89Å; I480-V596 HydrophobicContact CD1-CG2 3.83Å; I480-V596 HydrophobicContact CG1-CG2 4.03Å; I480-V596 HydrophobicContact CG2-CG2 3.85Å; I480-I599 HydrophobicContact CD1-CD1 4.26Å
481H97.5Very high94.8Very high43 Ų4341.6 Ų41.620%0.19921%0.212CC..EExtended strand (participates in β ladder)trans-96.1125.2179.1-57.8-103.3000110.6V472 V589 H590 K591V472-H481 VanDerWaalsContact CG2-ND1 3.3Å; V472-H481 WeakPolarHBondContact CG2-ND1 3.48Å; H481-V589 WeakPolarHBondContact O-CA 3.35Å; H481-V589 WeakPolarHBondContact O-CG1 3.42Å; H481-H590 PolarHBondContact O-CD2 3.25Å; H481-H590 PolarHBondContact O-N 3.02Å; H481-K591 HydrophobicContact CB-CB 3.9Å; H481-K591 PolarHBondContact N-O 3.38Å; H481-K591 PolarHBondContact O-N 2.76Å
482C97.1Very high94.8Very high0 Ų041.6 Ų41.60%021%0.212CC..EExtended strand (participates in β ladder)trans-121.8139.1-172-55.70000111.2S470 C471 M555 L588S470-C482 CarbonylContact C-O 3.54Å; S470-C482 WeakPolarHBondContact CA-O 3.14Å; S470-C482 WeakPolarHBondContact CB-O 3.25Å; C471-C482 PolarHBondContact N-O 2.81Å; C471-C482 PolarHBondContact O-N 3.13Å; C482-M555 HydrophobicContact CB-SD 3.46Å; C482-M555 WeakPolarHBondContact CB-SD 3.43Å; C482-M555 PolarHBondContact SG-SD 3.46Å; C482-L588 CarbonylContact C-O 3.59Å; C482-L588 WeakPolarHBondContact CA-O 3.38Å
483K96.5Very high94.7Very high109 Ų10941.3 Ų41.347%0.47421%0.21SC..EExtended strand (participates in β ladder)trans-88.5136.9162.2-178.1173.9-178.9176.10108.2E469 Y485 G587 L588E469-K483 CarbonylContact O-C 3.59Å; E469-K483 WeakPolarHBondContact O-CA 3.48Å; K483-Y485 HydrophobicContact CD-CE1 4.24Å; K483-Y485 HydrophobicContact CG-CE1 4.25Å; K483-G587 CarbonylContact O-C 3.55Å; K483-G587 WeakPolarHBondContact O-CA 3.27Å; K483-L588 PolarHBondContact N-O 3.49Å; K483-L588 PolarHBondContact O-N 3.32Å
484L96.8Very high94.5Very high2 Ų245.8 Ų45.81%0.0123%0.231CC..EExtended strand (participates in β ladder)trans-107.5158.1177-56.9178.9000110.4I468 E469 C471 P486 V493 F496 T497 F586I468-L484 HydrophobicContact CG2-CD1 4.1Å; E469-L484 PolarHBondContact O-N 3.4Å; C471-L484 HydrophobicContact CB-CD1 4.38Å; L484-P486 WeakPolarHBondContact O-CD 2.96Å; L484-V493 HydrophobicContact CB-CG1 4.23Å; L484-V493 HydrophobicContact CB-CG2 4.26Å; L484-V493 HydrophobicContact CD1-CG1 4.13Å; L484-F496 HydrophobicContact CD1-CD1 4.3Å; L484-F496 HydrophobicContact CD1-CE1 4.38Å; L484-F496 HydrophobicContact CD2-CD1 4.35Å; L484-F496 HydrophobicContact CD2-CE1 4.25Å; L484-T497 HydrophobicContact CD1-CG2 3.72Å; L484-F586 WeakPolarHBondContact CA-O 3.18Å; L484-F586 HydrophobicContact CD2-CD2 4.19Å; L484-F586 HydrophobicContact CD2-CE2 4.32Å
485Y95.3Very high94.4Very high34 Ų3443.6 Ų43.613%0.13322%0.221CC..  trans-116.265.9-177.7-56.7-43.1000112.5K483 K487 E488 C489 L547 I585 F586 L588K483-Y485 HydrophobicContact CD-CE1 4.24Å; K483-Y485 HydrophobicContact CG-CE1 4.25Å; Y485-K487 PolarHBondContact O-N 3.43Å; Y485-E488 WeakPolarHBondContact CB-OE2 3.29Å; Y485-E488 PolarHBondContact O-N 2.93Å; Y485-C489 PolarHBondContact O-N 2.89Å; Y485-L547 HydrophobicContact CD2-CD1 3.69Å; Y485-L547 HydrophobicContact CD2-CD2 3.69Å; Y485-L547 HydrophobicContact CD2-CG 4.36Å; Y485-L547 HydrophobicContact CE2-CD1 4.36Å; Y485-L547 HydrophobicContact CE2-CD2 3.59Å; Y485-L547 HydrophobicContact CG-CD1 4.23Å; Y485-L547 HydrophobicContact CG-CD2 4.27Å; Y485-I585 HydrophobicContact CD2-CG2 4.31Å; Y485-I585 HydrophobicContact CE2-CG2 4.06Å; Y485-F586 PolarHBondContact N-O 3.06Å; Y485-L588 VanDerWaalsContact OH-CB 3.23Å; Y485-L588 WeakPolarHBondContact OH-CB 3.39Å
486P89.8Confident94.4Very high10 Ų1043.1 Ų43.17%0.06522%0.218CC..THydrogen-bonded Turntrans-69.8-17.6-173.627-34.7000114.1L467 E469 L484 P490 V493L467-P486 HydrophobicContact CB-CB 3.95Å; L467-P486 HydrophobicContact CB-CG 3.64Å; L467-P486 HydrophobicContact CD1-CB 4.42Å; L467-P486 HydrophobicContact CD1-CG 4.26Å; L467-P486 HydrophobicContact CD2-CB 3.78Å; L467-P486 HydrophobicContact CD2-CG 4.38Å; L467-P486 HydrophobicContact CG-CB 4.24Å; L467-P486 HydrophobicContact CG-CG 4.29Å; E469-P486 HydrophobicContact CG-CG 3.9Å; L484-P486 WeakPolarHBondContact O-CD 2.96Å; P486-P490 VanDerWaalsContact O-CA 3.29Å; P486-P490 WeakPolarHBondContact O-CA 3.47Å; P486-P490 WeakPolarHBondContact O-CB 3.42Å; P486-V493 HydrophobicContact CB-CB 4.29Å; P486-V493 HydrophobicContact CB-CG1 3.98Å; P486-V493 HydrophobicContact CB-CG2 4.48Å
487K88Confident94.4Very high136 Ų13639.9 Ų39.959%0.59120%0.198SC*.THydrogen-bonded Turntrans-83.1-37.9176.6-65.7179.7-177.8172.50111.2L467 Y485L467-K487 HydrophobicContact CD1-CG 3.89Å; Y485-K487 PolarHBondContact O-N 3.43Å
488E91Very high94.1Very high68 Ų6837 Ų3732%0.31819%0.186SC..THydrogen-bonded Turntrans-83.6-36.3-177.3-61.680.1176.900112.2Y485 H544 L547Y485-E488 WeakPolarHBondContact CB-OE2 3.29Å; Y485-E488 PolarHBondContact O-N 2.93Å; E488-H544 HydrophobicContact CB-CB 4.03Å; E488-H544 HydrophobicContact CG-CB 4.45Å; E488-L547 HydrophobicContact CB-CD1 3.81Å; E488-L547 HydrophobicContact CG-CD1 4.29Å
489C91.4Very high93.8Very high0 Ų036.2 Ų36.20%018%0.175CC..SBendtrans-134.663.1-176.7-54.30000111.1Y485 K491 T492 V493 E542 T584 I585 F586Y485-C489 PolarHBondContact O-N 2.89Å; C489-K491 PolarHBondContact O-N 3.04Å; C489-T492 PolarHBondContact O-N 2.88Å; C489-V493 WeakPolarHBondContact O-CG2 3.46Å; C489-V493 PolarHBondContact O-N 3.4Å; C489-E542 WeakPolarHBondContact CA-OE2 3.37Å; C489-E542 HydrophobicContact CB-CB 4.04Å; C489-E542 WeakPolarHBondContact CB-OE2 3.31Å; C489-E542 PolarHBondContact SG-O 3.27Å; C489-E542 VanDerWaalsContact SG-O 3.33Å; C489-T584 HydrophobicContact CB-CG2 4.24Å; C489-I585 PolarHBondContact SG-O 3.26Å; C489-F586 HydrophobicContact CB-CB 4.33Å
490P91.8Very high93.5Very high68 Ų6833.2 Ų33.244%0.44216%0.159SC..Hα-helixtrans-57.5-44.6-172.821.7-33.3000113.2P486 E494 E542P486-P490 VanDerWaalsContact O-CA 3.29Å; P486-P490 WeakPolarHBondContact O-CA 3.47Å; P486-P490 WeakPolarHBondContact O-CB 3.42Å; P490-E494 VanDerWaalsContact O-CB 3.27Å; P490-E494 WeakPolarHBondContact O-CB 3.4Å; P490-E494 PolarHBondContact O-N 3.45Å; P490-E542 WeakPolarHBondContact CD-OE1 3.24Å; P490-E542 WeakPolarHBondContact CG-OE1 3.15Å
491K91.5Very high93Very high80 Ų8039.2 Ų39.235%0.34819%0.185SC..Hα-helixtrans-69.5-40-178.3-71.8-174.8163.7-170.70111.8C489 V493 E494 N495 W535 E540 E542C489-K491 PolarHBondContact O-N 3.04Å; K491-V493 VanDerWaalsContact C-N 3.35Å; K491-V493 PolarHBondContact O-N 3.49Å; K491-E494 PolarHBondContact O-N 3.09Å; K491-N495 VanDerWaalsContact O-CB 3.29Å; K491-N495 WeakPolarHBondContact O-CB 3.29Å; K491-N495 PolarHBondContact O-N 3.03Å; K491-W535 HydrophobicContact CB-CH2 4.1Å; K491-W535 WeakPolarHBondContact O-CH2 3.48Å; K491-E540 HydrophobicContact CD-CG 4.46Å; K491-E540 WeakPolarHBondContact CD-OE1 3.28Å; K491-E540 WeakPolarHBondContact CE-OE1 3.1Å; K491-E540 IonicContact NZ-OE1 3.27Å; K491-E540 PolarHBondContact NZ-OE1 3.43Å; K491-E540 IonicContact NZ-OE2 3.54Å; K491-E540 PolarHBondContact NZ-OE2 2.96Å; K491-E540 VanDerWaalsContact NZ-OE2 3.08Å; K491-E542 WeakPolarHBondContact CB-OE1 3.46Å; K491-E542 PolarHBondContact N-OE1 2.9Å; K491-E542 PolarHBondContact N-OE2 3.36Å
492T95.4Very high92.4Very high0 Ų043.2 Ų43.20%021%0.208CC..Hα-helixtrans-65.4-42.4180-52.70000110.9C489 F496 F539 E542 M557 T584 F586C489-T492 PolarHBondContact O-N 2.88Å; T492-F496 WeakPolarHBondContact O-CB 3.29Å; T492-F496 PolarHBondContact O-N 2.52Å; T492-F539 HydrophobicContact CG2-CZ 4.41Å; T492-E542 VanDerWaalsContact CB-OE2 3.29Å; T492-E542 WeakPolarHBondContact CB-OE2 3.37Å; T492-E542 PolarHBondContact N-OE2 3.42Å; T492-E542 PolarHBondContact OG1-OE2 3.32Å; T492-M557 HydrophobicContact CG2-CG 3.45Å; T492-M557 VanDerWaalsContact CG2-CG 3.45Å; T492-M557 HydrophobicContact CG2-SD 3.69Å; T492-T584 HydrophobicContact CG2-CG2 4.14Å; T492-T584 WeakPolarHBondContact OG1-CG2 3.23Å; T492-F586 HydrophobicContact CG2-CB 3.51Å; T492-F586 HydrophobicContact CG2-CD1 3.73Å; T492-F586 HydrophobicContact CG2-CD2 4.33Å; T492-F586 HydrophobicContact CG2-CG 3.6Å
493V95.6Very high91.8Very high4 Ų444.4 Ų44.42%0.02422%0.22CC..Hα-helixtrans-69.2-40.1176.4176.50000111.3L484 P486 C489 K491 F496 T497 F586L484-V493 HydrophobicContact CB-CG1 4.23Å; L484-V493 HydrophobicContact CB-CG2 4.26Å; L484-V493 HydrophobicContact CD1-CG1 4.13Å; P486-V493 HydrophobicContact CB-CB 4.29Å; P486-V493 HydrophobicContact CB-CG1 3.98Å; P486-V493 HydrophobicContact CB-CG2 4.48Å; C489-V493 WeakPolarHBondContact O-CG2 3.46Å; C489-V493 PolarHBondContact O-N 3.4Å; K491-V493 VanDerWaalsContact C-N 3.35Å; K491-V493 PolarHBondContact O-N 3.49Å; V493-F496 PolarHBondContact O-N 3Å; V493-T497 HydrophobicContact CG1-CG2 3.9Å; V493-T497 WeakPolarHBondContact O-CB 3.37Å; V493-T497 WeakPolarHBondContact O-CG2 3.38Å; V493-T497 PolarHBondContact O-N 3.34Å; V493-T497 PolarHBondContact O-OG1 3.27Å; V493-F586 HydrophobicContact CG2-CB 4.3Å
494E93.3Very high91.5Very high96 Ų9642.4 Ų42.445%0.44921%0.21SC..Hα-helixtrans-58.8-49.4173.7-176.3179.1-159.200111.4P490 K491 F496 T497 T498 M534P490-E494 VanDerWaalsContact O-CB 3.27Å; P490-E494 WeakPolarHBondContact O-CB 3.4Å; P490-E494 PolarHBondContact O-N 3.45Å; K491-E494 PolarHBondContact O-N 3.09Å; E494-F496 PolarHBondContact O-N 3.17Å; E494-T497 PolarHBondContact O-N 2.93Å; E494-T497 PolarHBondContact O-OG1 3.16Å; E494-T498 WeakPolarHBondContact O-CB 3.43Å; E494-T498 PolarHBondContact O-N 3.32Å; E494-T498 PolarHBondContact O-OG1 3.39Å; E494-M534 HydrophobicContact CG-SD 4.01Å
495N94.2Very high91.4Very high0 Ų042.3 Ų42.30%021%0.21CC..Hα-helixtrans-56.9-52.9176.2176.963.5000111.7K491 L499 S533 M534 W535 F539 G566K491-N495 VanDerWaalsContact O-CB 3.29Å; K491-N495 WeakPolarHBondContact O-CB 3.29Å; K491-N495 PolarHBondContact O-N 3.03Å; N495-L499 WeakPolarHBondContact O-CB 3.21Å; N495-L499 WeakPolarHBondContact O-CG 3.41Å; N495-L499 PolarHBondContact O-N 3.2Å; N495-L499 VanDerWaalsContact O-N 3.09Å; N495-S533 VanDerWaalsContact OD1-CA 3.25Å; N495-S533 WeakPolarHBondContact OD1-CA 3.17Å; N495-S533 WeakPolarHBondContact OD1-CB 3.38Å; N495-M534 HydrophobicContact CB-CG 4.4Å; N495-M534 PolarHBondContact OD1-N 3.02Å; N495-W535 HydrophobicContact CB-CH2 3.87Å; N495-W535 HydrophobicContact CB-CZ3 3.75Å; N495-F539 HydrophobicContact CB-CE1 4.12Å; N495-F539 HydrophobicContact CB-CZ 4.09Å; N495-F539 WeakPolarHBondContact ND2-CE1 3.33Å; N495-G566 PolarHBondContact ND2-O 2.97Å
496F97.2Very high91.2Very high0 Ų044.3 Ų44.30%022%0.223CC..Hα-helixtrans-61.3-48.8-178.8174.4-98.5000112.1I473 L484 T492 V493 E494 A500 Y505 M555 F569 F586 I620I473-F496 HydrophobicContact CD1-CZ 4.47Å; L484-F496 HydrophobicContact CD1-CD1 4.3Å; L484-F496 HydrophobicContact CD1-CE1 4.38Å; L484-F496 HydrophobicContact CD2-CD1 4.35Å; L484-F496 HydrophobicContact CD2-CE1 4.25Å; T492-F496 WeakPolarHBondContact O-CB 3.29Å; T492-F496 PolarHBondContact O-N 2.52Å; V493-F496 PolarHBondContact O-N 3Å; E494-F496 PolarHBondContact O-N 3.17Å; F496-A500 VanDerWaalsContact O-CB 3.28Å; F496-A500 WeakPolarHBondContact O-CB 3.36Å; F496-A500 PolarHBondContact O-N 3.47Å; F496-Y505 AromaticContact CD2-CE2 3.84Å; F496-Y505 HydrophobicContact CD2-CE2 3.84Å; F496-Y505 HydrophobicContact CE2-CE2 4.06Å; F496-M555 HydrophobicContact CE2-CE 4.39Å; F496-M555 HydrophobicContact CZ-CE 4.2Å; F496-F569 HydrophobicContact CD2-CD1 4.39Å; F496-F569 HydrophobicContact CD2-CE1 4.25Å; F496-F569 HydrophobicContact CE2-CD1 4.24Å; F496-F569 AromaticContact CE2-CE1 3.7Å; F496-F569 HydrophobicContact CE2-CE1 3.7Å; F496-F569 AromaticContact CE2-CZ 3.88Å; F496-F569 HydrophobicContact CE2-CZ 3.88Å; F496-F586 HydrophobicContact CB-CD2 4.48Å; F496-F586 HydrophobicContact CB-CE2 4.01Å; F496-F586 HydrophobicContact CD1-CE2 4.05Å; F496-F586 AromaticContact CD2-CE2 3.81Å; F496-F586 HydrophobicContact CD2-CE2 3.81Å; F496-F586 HydrophobicContact CD2-CZ 4.01Å; F496-F586 HydrophobicContact CE2-CE2 4.28Å; F496-F586 HydrophobicContact CE2-CZ 4.43Å; F496-F586 HydrophobicContact CG-CD2 4.49Å; F496-F586 AromaticContact CG-CE2 3.67Å; F496-F586 HydrophobicContact CG-CE2 3.67Å; F496-F586 HydrophobicContact CG-CZ 4.31Å; F496-I620 HydrophobicContact CE2-CD1 4.14Å; F496-I620 HydrophobicContact CZ-CD1 3.87Å; F496-I620 HydrophobicContact CZ-CG2 4.49Å
497T94Very high91.3Very high10 Ų1046 Ų466%0.06124%0.242CC..Hα-helixtrans-71.1-35.4-174.757.70000112.5I468 L484 V493 E494 A500 K501 F622I468-T497 HydrophobicContact CB-CG2 4.12Å; I468-T497 HydrophobicContact CD1-CG2 4.21Å; I468-T497 HydrophobicContact CG2-CG2 3.94Å; L484-T497 HydrophobicContact CD1-CG2 3.72Å; V493-T497 HydrophobicContact CG1-CG2 3.9Å; V493-T497 WeakPolarHBondContact O-CB 3.37Å; V493-T497 WeakPolarHBondContact O-CG2 3.38Å; V493-T497 PolarHBondContact O-N 3.34Å; V493-T497 PolarHBondContact O-OG1 3.27Å; E494-T497 PolarHBondContact O-N 2.93Å; E494-T497 PolarHBondContact O-OG1 3.16Å; T497-A500 PolarHBondContact O-N 3.04Å; T497-K501 WeakPolarHBondContact O-CG 3.4Å; T497-K501 PolarHBondContact O-N 3.2Å; T497-F622 HydrophobicContact CG2-CE1 3.73Å; T497-F622 HydrophobicContact CG2-CZ 4.06Å
498T88.3Confident91.7Very high24 Ų2439.9 Ų39.915%0.14722%0.216CC..Hα-helixtrans-68.7-46.6177-56.40000111.4E494 A500 K501 N502 M534E494-T498 WeakPolarHBondContact O-CB 3.43Å; E494-T498 PolarHBondContact O-N 3.32Å; E494-T498 PolarHBondContact O-OG1 3.39Å; T498-A500 VanDerWaalsContact C-N 3.3Å; T498-A500 PolarHBondContact O-N 2.8Å; T498-K501 PolarHBondContact O-N 3.25Å; T498-N502 VanDerWaalsContact O-CG 3.31Å; T498-N502 PolarHBondContact O-N 3.08Å; T498-N502 PolarHBondContact O-ND2 3.31Å; T498-M534 HydrophobicContact CG2-CB 4.46Å; T498-M534 HydrophobicContact CG2-CE 3.79Å; T498-M534 HydrophobicContact CG2-SD 3.99Å
499L90.5Very high91.9Very high9 Ų937.3 Ų37.35%0.04721%0.205CC..Hα-helixtrans-58.3-44.3174.4-71.3175.7000111.1N495 N502 G503 Y504 Y505 M534N495-L499 WeakPolarHBondContact O-CB 3.21Å; N495-L499 WeakPolarHBondContact O-CG 3.41Å; N495-L499 PolarHBondContact O-N 3.2Å; N495-L499 VanDerWaalsContact O-N 3.09Å; L499-N502 PolarHBondContact O-N 3.28Å; L499-G503 PolarHBondContact O-N 2.93Å; L499-Y504 HydrophobicContact CB-CD1 4.2Å; L499-Y504 HydrophobicContact CB-CG 4.16Å; L499-Y504 HydrophobicContact CD1-CD1 4.28Å; L499-Y504 HydrophobicContact CD1-CE1 4.45Å; L499-Y504 HydrophobicContact CD2-CD1 4.06Å; L499-Y504 HydrophobicContact CD2-CD2 3.79Å; L499-Y504 HydrophobicContact CD2-CE1 4.47Å; L499-Y504 HydrophobicContact CD2-CE2 4.2Å; L499-Y504 HydrophobicContact CD2-CG 3.7Å; L499-Y504 HydrophobicContact CG-CD1 4.41Å; L499-Y504 HydrophobicContact CG-CG 4.4Å; L499-Y504 WeakPolarHBondContact O-CB 3.11Å; L499-Y504 PolarHBondContact O-N 2.83Å; L499-Y505 HydrophobicContact CB-CD2 4.23Å; L499-Y505 HydrophobicContact CB-CE2 3.57Å; L499-Y505 HydrophobicContact CD1-CE2 4.46Å; L499-Y505 WeakPolarHBondContact CD1-OH 2.83Å; L499-M534 HydrophobicContact CD2-CB 4.14Å; L499-M534 HydrophobicContact CG-CB 4.22Å
500A91.4Very high92.2Very high4 Ų437.5 Ų37.53%0.03321%0.206CC..Hα-helixtrans-59.8-48.4176.200000113.3F496 T497 T498 N502 G503 Y505 I620 F622F496-A500 VanDerWaalsContact O-CB 3.28Å; F496-A500 WeakPolarHBondContact O-CB 3.36Å; F496-A500 PolarHBondContact O-N 3.47Å; T497-A500 PolarHBondContact O-N 3.04Å; T498-A500 VanDerWaalsContact C-N 3.3Å; T498-A500 PolarHBondContact O-N 2.8Å; A500-N502 PolarHBondContact O-N 2.98Å; A500-G503 PolarHBondContact O-N 2.63Å; A500-Y505 HydrophobicContact CB-CD2 3.96Å; A500-Y505 HydrophobicContact CB-CE2 4.36Å; A500-I620 HydrophobicContact CB-CB 3.9Å; A500-I620 HydrophobicContact CB-CD1 4.07Å; A500-I620 HydrophobicContact CB-CG2 3.96Å; A500-F622 HydrophobicContact CB-CE2 4.05Å; A500-F622 HydrophobicContact CB-CZ 3.68Å
501K86.8Confident92.3Very high127 Ų12734.7 Ų34.755%0.55219%0.187SC*.Hα-helixtrans-60.3-34.2177.1-76176.5179.3176.30112.9T497 T498 G503 F622T497-K501 WeakPolarHBondContact O-CG 3.4Å; T497-K501 PolarHBondContact O-N 3.2Å; T498-K501 PolarHBondContact O-N 3.25Å; K501-G503 PolarHBondContact O-N 3.12Å; K501-F622 HydrophobicContact CG-CD2 4.12Å; K501-F622 HydrophobicContact CG-CE2 3.64Å
502N84.2Confident92.5Very high126 Ų12635.9 Ų35.967%0.67419%0.189SC*.THydrogen-bonded Turntrans-78.42.1177.1-67.4-18.5000113.3T498 L499 A500 Y504T498-N502 VanDerWaalsContact O-CG 3.31Å; T498-N502 PolarHBondContact O-N 3.08Å; T498-N502 PolarHBondContact O-ND2 3.31Å; L499-N502 PolarHBondContact O-N 3.28Å; A500-N502 PolarHBondContact O-N 2.98Å; N502-Y504 PolarHBondContact O-N 2.81Å
503G84.7Confident92.5Very high25 Ų2535.9 Ų35.926%0.25819%0.189SC..THydrogen-bonded Turntrans71.514.9-17800000114L499 A500 K501 Y505 N506L499-G503 PolarHBondContact O-N 2.93Å; A500-G503 PolarHBondContact O-N 2.63Å; K501-G503 PolarHBondContact O-N 3.12Å; G503-Y505 PolarHBondContact O-N 3.37Å; G503-N506 WeakPolarHBondContact CA-ND2 3.25Å; G503-N506 VanDerWaalsContact O-CB 3.28Å; G503-N506 WeakPolarHBondContact O-CB 3.18Å; G503-N506 PolarHBondContact O-N 2.85Å
504Y90.2Very high92.5Very high67 Ų6737.3 Ų37.326%0.26320%0.196SC..THydrogen-bonded Turntrans-61-31.5-176.7-174.9-89.1000113.2L499 N502 N508 P524 G531 A532 S567L499-Y504 HydrophobicContact CB-CD1 4.2Å; L499-Y504 HydrophobicContact CB-CG 4.16Å; L499-Y504 HydrophobicContact CD1-CD1 4.28Å; L499-Y504 HydrophobicContact CD1-CE1 4.45Å; L499-Y504 HydrophobicContact CD2-CD1 4.06Å; L499-Y504 HydrophobicContact CD2-CD2 3.79Å; L499-Y504 HydrophobicContact CD2-CE1 4.47Å; L499-Y504 HydrophobicContact CD2-CE2 4.2Å; L499-Y504 HydrophobicContact CD2-CG 3.7Å; L499-Y504 HydrophobicContact CG-CD1 4.41Å; L499-Y504 HydrophobicContact CG-CG 4.4Å; L499-Y504 WeakPolarHBondContact O-CB 3.11Å; L499-Y504 PolarHBondContact O-N 2.83Å; N502-Y504 PolarHBondContact O-N 2.81Å; Y504-N508 PolarHBondContact O-ND2 2.93Å; Y504-N508 PolarHBondContact O-OD1 3.04Å; Y504-P524 HydrophobicContact CD1-CG 4.18Å; Y504-P524 HydrophobicContact CE1-CG 3.42Å; Y504-P524 VanDerWaalsContact CE1-CG 3.42Å; Y504-P524 HydrophobicContact CE2-CG 4.03Å; Y504-P524 WeakPolarHBondContact OH-CG 3.26Å; Y504-G531 WeakPolarHBondContact OH-CA 3.46Å; Y504-A532 PolarHBondContact OH-N 2.86Å; Y504-A532 PolarHBondContact OH-O 3.27Å; Y504-S567 VanDerWaalsContact CE1-CB 3.47Å
505Y95.4Very high92.4Very high0 Ų037.9 Ų37.90%020%0.197CC..THydrogen-bonded Turntrans-85.7-7.9178.7-66.3-64.6000113.6F496 L499 A500 G503 G507 N508 S567 F569 I617 I620F496-Y505 AromaticContact CD2-CE2 3.84Å; F496-Y505 HydrophobicContact CD2-CE2 3.84Å; F496-Y505 HydrophobicContact CE2-CE2 4.06Å; L499-Y505 HydrophobicContact CB-CD2 4.23Å; L499-Y505 HydrophobicContact CB-CE2 3.57Å; L499-Y505 HydrophobicContact CD1-CE2 4.46Å; L499-Y505 WeakPolarHBondContact CD1-OH 2.83Å; A500-Y505 HydrophobicContact CB-CD2 3.96Å; A500-Y505 HydrophobicContact CB-CE2 4.36Å; G503-Y505 PolarHBondContact O-N 3.37Å; Y505-G507 PolarHBondContact O-N 2.79Å; Y505-N508 VanDerWaalsContact O-CB 3.31Å; Y505-N508 WeakPolarHBondContact O-CB 3.42Å; Y505-N508 PolarHBondContact O-N 3.41Å; Y505-S567 WeakPolarHBondContact CE1-O 3.49Å; Y505-S567 PolarHBondContact OH-O 2.96Å; Y505-S567 VanDerWaalsContact OH-O 3.11Å; Y505-F569 HydrophobicContact CD1-CE1 4.36Å; Y505-F569 HydrophobicContact CE1-CD1 4.37Å; Y505-F569 HydrophobicContact CE1-CE1 4.03Å; Y505-I617 WeakPolarHBondContact O-CB 3.16Å; Y505-I620 HydrophobicContact CD2-CD1 3.68Å; Y505-I620 HydrophobicContact CG-CD1 3.94Å
506N90.9Very high92.3Very high76 Ų7641.7 Ų41.741%0.40622%0.224SC..THydrogen-bonded Turntrans-70.5125-175.9-59.3-0000109.4G503 N508 S619G503-N506 WeakPolarHBondContact CA-ND2 3.25Å; G503-N506 VanDerWaalsContact O-CB 3.28Å; G503-N506 WeakPolarHBondContact O-CB 3.18Å; G503-N506 PolarHBondContact O-N 2.85Å; N506-N508 VanDerWaalsContact C-N 3.28Å; N506-S619 WeakPolarHBondContact OD1-CA 3.15Å
507G92Very high92.2Very high46 Ų4643.9 Ų43.947%0.47423%0.233SC..THydrogen-bonded Turntrans84-6.8-17300000114.3Y505 V509 I617Y505-G507 PolarHBondContact O-N 2.79Å; G507-V509 PolarHBondContact O-N 2.96Å; G507-I617 WeakPolarHBondContact CA-O 3.39Å; G507-I617 PolarHBondContact N-O 2.81Å
508N96.7Very high92.4Very high7 Ų743.7 Ų43.74%0.03723%0.232CC..  trans-66.4128.6-179.5-70.38.2000110.4Y504 Y505 N506 P524 S616 I617Y504-N508 PolarHBondContact O-ND2 2.93Å; Y504-N508 PolarHBondContact O-OD1 3.04Å; Y505-N508 VanDerWaalsContact O-CB 3.31Å; Y505-N508 WeakPolarHBondContact O-CB 3.42Å; Y505-N508 PolarHBondContact O-N 3.41Å; N506-N508 VanDerWaalsContact C-N 3.28Å; N508-P524 WeakPolarHBondContact OD1-CA 3.38Å; N508-S616 CarbonylContact O-C 3.53Å; N508-S616 VanDerWaalsContact O-CA 3.29Å; N508-S616 WeakPolarHBondContact O-CA 3.42Å; N508-I617 PolarHBondContact O-N 2.93Å
509V94.4Very high92.8Very high14 Ų1442.6 Ų42.69%0.08523%0.225CC..BIsolated β-bridgetrans-87.2147.1-177.5-63.60000111.9G507 H511 T521 E614 I615G507-V509 PolarHBondContact O-N 2.96Å; V509-H511 HydrophobicContact CG2-CB 4.11Å; V509-H511 PolarHBondContact O-N 2.7Å; V509-H511 PolarHBondContact O-ND1 3.28Å; V509-T521 PolarHBondContact O-OG1 2.91Å; V509-E614 HydrophobicContact CB-CG 4.29Å; V509-E614 HydrophobicContact CG1-CG 3.41Å; V509-E614 VanDerWaalsContact CG1-CG 3.41Å; V509-E614 VanDerWaalsContact CG1-OE1 3.31Å; V509-E614 WeakPolarHBondContact CG1-OE1 3.32Å; V509-I615 CarbonylContact C-O 3.6Å; V509-I615 WeakPolarHBondContact CA-O 3.39Å
510F97.2Very high93.2Very high4 Ų442.9 Ų42.92%0.01823%0.226CC..  trans-71.978164.8-69.8-91.1000109.4T475 R512 V513 I519 Q520 T521 I599 P611 I615 I617T475-F510 HydrophobicContact CG2-CE2 3.91Å; T475-F510 HydrophobicContact CG2-CZ 4.07Å; F510-R512 VanDerWaalsContact C-N 3.26Å; F510-R512 PolarHBondContact O-N 3.22Å; F510-V513 HydrophobicContact CB-CG2 4.29Å; F510-I519 HydrophobicContact CD1-CB 4.15Å; F510-I519 HydrophobicContact CD1-CD1 4.17Å; F510-I519 HydrophobicContact CD1-CG1 4.32Å; F510-I519 HydrophobicContact CE1-CD1 3.79Å; F510-I519 HydrophobicContact CE1-CG1 4.21Å; F510-Q520 CarbonylContact C-O 3.55Å; F510-Q520 VanDerWaalsContact CA-O 3.27Å; F510-Q520 WeakPolarHBondContact CA-O 3.29Å; F510-T521 HydrophobicContact CD1-CG2 4.1Å; F510-T521 HydrophobicContact CE1-CG2 3.75Å; F510-T521 HydrophobicContact CZ-CG2 4.22Å; F510-I599 HydrophobicContact CB-CG2 4.46Å; F510-I599 HydrophobicContact CD1-CG2 4.34Å; F510-I599 HydrophobicContact CE2-CD1 4.15Å; F510-I599 HydrophobicContact CG-CG2 4.23Å; F510-I599 HydrophobicContact CZ-CD1 4.18Å; F510-P611 VanDerWaalsContact O-CD 3.25Å; F510-P611 WeakPolarHBondContact O-CD 3.04Å; F510-P611 WeakPolarHBondContact O-CG 3.46Å; F510-I615 HydrophobicContact CD2-CB 4.21Å; F510-I615 HydrophobicContact CD2-CG2 3.72Å; F510-I615 WeakPolarHBondContact CD2-O 3.43Å; F510-I615 HydrophobicContact CE2-CG2 4.19Å; F510-I615 PolarHBondContact N-O 3.14Å; F510-I617 HydrophobicContact CE2-CG1 4.04Å; F510-I617 HydrophobicContact CZ-CG1 4.27Å
511H94.8Very high93.5Very high10 Ų1042.7 Ų42.75%0.04622%0.224CC..  trans-71.7-17.5-169.855.4-91.1000113.7V509 Q520 G526 G528 Q568 R610V509-H511 HydrophobicContact CG2-CB 4.11Å; V509-H511 PolarHBondContact O-N 2.7Å; V509-H511 PolarHBondContact O-ND1 3.28Å; H511-Q520 PolarHBondContact N-O 2.82Å; H511-G526 VanDerWaalsContact CB-O 3.26Å; H511-G526 WeakPolarHBondContact CB-O 3.34Å; H511-G528 VanDerWaalsContact CD2-CA 3.41Å; H511-G528 WeakPolarHBondContact CD2-CA 3.36Å; H511-G528 WeakPolarHBondContact NE2-CA 3.34Å; H511-Q568 PolarHBondContact NE2-OE1 3.09Å; H511-R610 WeakPolarHBondContact O-CA 3.21Å
512R95.3Very high93.9Very high105 Ų10536.6 Ų36.640%0.39620%0.198SC..EExtended strand (participates in β ladder)trans-140.9119.1178.5-175.6-176.7-179.2-162.83.4111.2F510 I514 Q520 N609F510-R512 VanDerWaalsContact C-N 3.26Å; F510-R512 PolarHBondContact O-N 3.22Å; R512-I514 HydrophobicContact CG-CG1 4.42Å; R512-Q520 HydrophobicContact CB-CB 4.19Å; R512-Q520 WeakPolarHBondContact O-CB 3.25Å; R512-Q520 PolarHBondContact O-N 3.02Å; R512-N609 HydrophobicContact CG-CB 4.21Å
513V96.4Very high94.4Very high0 Ų030.6 Ų30.60%017%0.166CC..EExtended strand (participates in β ladder)trans-129.6112.2-179.2170.40000109.2F510 I519 I599 T604 N609 P611F510-V513 HydrophobicContact CB-CG2 4.29Å; V513-I519 HydrophobicContact CG1-CG2 4.06Å; V513-I519 HydrophobicContact CG2-CB 4.31Å; V513-I519 HydrophobicContact CG2-CG2 4.07Å; V513-I599 HydrophobicContact CG2-CG2 4.27Å; V513-T604 HydrophobicContact CB-CG2 3.84Å; V513-T604 HydrophobicContact CG1-CG2 4.01Å; V513-N609 PolarHBondContact N-O 3.46Å; V513-N609 WeakPolarHBondContact O-CB 3.37Å; V513-P611 HydrophobicContact CB-CG 4.16Å; V513-P611 HydrophobicContact CG2-CG 3.72Å
514I93.6Very high94.5Very high34 Ų3432.5 Ų32.517%0.17417%0.174CC..EExtended strand (participates in β ladder)trans-107116.7179.5-58174000108.4R512 S516 F517 I518 N600 N609R512-I514 HydrophobicContact CG-CG1 4.42Å; I514-S516 PolarHBondContact O-N 3.09Å; I514-F517 HydrophobicContact CB-CB 4.05Å; I514-F517 HydrophobicContact CB-CD1 4.11Å; I514-F517 HydrophobicContact CD1-CD1 3.89Å; I514-F517 HydrophobicContact CD1-CE1 4.36Å; I514-F517 HydrophobicContact CG2-CB 3.77Å; I514-F517 HydrophobicContact CG2-CD1 4.05Å; I514-F517 HydrophobicContact CG2-CG 4.42Å; I514-F517 PolarHBondContact O-N 3.22Å; I514-I518 HydrophobicContact CB-CG1 4.44Å; I514-I518 HydrophobicContact CD1-CG1 4.37Å; I514-I518 PolarHBondContact N-O 3.21Å; I514-I518 PolarHBondContact O-N 3.33Å; I514-N600 PolarHBondContact O-ND2 3.21Å; I514-N609 HydrophobicContact CG1-CB 4.03Å
515K92.3Very high94.3Very high108 Ų10833.9 Ų33.947%0.4719%0.189SC..THydrogen-bonded Turntrans-54.3132.5-179.3-70.4-167.1174.6-163.50111F517K515-F517 PolarHBondContact O-N 3.19Å
516S91.8Very high93.9Very high79 Ų7934.1 Ų34.155%0.55219%0.191SC*.THydrogen-bonded Turntrans60.223.3-179.1-48.40000114.4I514 T574 N600I514-S516 PolarHBondContact O-N 3.09Å; S516-T574 WeakPolarHBondContact O-CG2 3.48Å; S516-T574 PolarHBondContact O-OG1 2.91Å; S516-N600 PolarHBondContact N-OD1 2.88Å
517F96.1Very high93.7Very high47 Ų4733.8 Ų33.821%0.20620%0.195CC..THydrogen-bonded Turntrans-136.3-76.1176.5-176-140.3000113.2I514 K515 T572 V573 A576 H578 L579I514-F517 HydrophobicContact CB-CB 4.05Å; I514-F517 HydrophobicContact CB-CD1 4.11Å; I514-F517 HydrophobicContact CD1-CD1 3.89Å; I514-F517 HydrophobicContact CD1-CE1 4.36Å; I514-F517 HydrophobicContact CG2-CB 3.77Å; I514-F517 HydrophobicContact CG2-CD1 4.05Å; I514-F517 HydrophobicContact CG2-CG 4.42Å; I514-F517 PolarHBondContact O-N 3.22Å; K515-F517 PolarHBondContact O-N 3.19Å; F517-T572 WeakPolarHBondContact O-CA 3.34Å; F517-V573 WeakPolarHBondContact O-CG2 3.3Å; F517-V573 PolarHBondContact O-N 2.73Å; F517-A576 HydrophobicContact CD2-CB 4.42Å; F517-A576 HydrophobicContact CE2-CB 3.81Å; F517-H578 AromaticContact CE2-CE1 3.59Å; F517-H578 AromaticContact CE2-NE2 3.56Å; F517-H578 AromaticContact CZ-NE2 3.49Å; F517-H578 WeakPolarHBondContact CZ-NE2 3.34Å; F517-L579 HydrophobicContact CE2-CD1 4.05Å; F517-L579 HydrophobicContact CZ-CD1 3.94Å; F517-L579 HydrophobicContact CZ-CD2 4.41Å; F517-L579 HydrophobicContact CZ-CG 4.49Å
518I97Very high93.4Very high6 Ų632.8 Ų32.83%0.03119%0.185CC..EExtended strand (participates in β ladder)trans-145.2158.8-174.264170.6000113.1I514 Q520 F570 I571 T572 N600I514-I518 HydrophobicContact CB-CG1 4.44Å; I514-I518 HydrophobicContact CD1-CG1 4.37Å; I514-I518 PolarHBondContact N-O 3.21Å; I514-I518 PolarHBondContact O-N 3.33Å; I518-Q520 HydrophobicContact CD1-CB 4.49Å; I518-F570 HydrophobicContact CB-CB 4.22Å; I518-F570 HydrophobicContact CB-CD2 4.24Å; I518-F570 HydrophobicContact CB-CG 4.48Å; I518-F570 HydrophobicContact CD1-CB 4.05Å; I518-F570 HydrophobicContact CD1-CD2 4.48Å; I518-F570 HydrophobicContact CD1-CG 4.13Å; I518-F570 HydrophobicContact CG2-CD2 3.67Å; I518-F570 HydrophobicContact CG2-CE2 4.21Å; I518-F570 HydrophobicContact CG2-CG 4.31Å; I518-I571 VanDerWaalsContact CA-O 3.3Å; I518-I571 WeakPolarHBondContact CA-O 3.17Å; I518-T572 HydrophobicContact CG2-CG2 4.24Å; I518-N600 PolarHBondContact O-ND2 3.44Å
519I97.6Very high92.8Very high1 Ų138.7 Ų38.71%0.00522%0.222CC..EExtended strand (participates in β ladder)trans-116.312915962.6172.2000108.4F510 V513 F570 I571 V596 I599 N600F510-I519 HydrophobicContact CD1-CB 4.15Å; F510-I519 HydrophobicContact CD1-CD1 4.17Å; F510-I519 HydrophobicContact CD1-CG1 4.32Å; F510-I519 HydrophobicContact CE1-CD1 3.79Å; F510-I519 HydrophobicContact CE1-CG1 4.21Å; V513-I519 HydrophobicContact CG1-CG2 4.06Å; V513-I519 HydrophobicContact CG2-CB 4.31Å; V513-I519 HydrophobicContact CG2-CG2 4.07Å; I519-F570 CarbonylContact O-C 3.57Å; I519-F570 WeakPolarHBondContact O-CA 3.31Å; I519-F570 VanDerWaalsContact O-CB 3.32Å; I519-F570 WeakPolarHBondContact O-CB 3.29Å; I519-I571 HydrophobicContact CD1-CB 4.33Å; I519-I571 HydrophobicContact CD1-CD1 4.39Å; I519-I571 HydrophobicContact CG1-CB 3.83Å; I519-I571 HydrophobicContact CG1-CG1 4.37Å; I519-I571 PolarHBondContact N-O 2.96Å; I519-I571 PolarHBondContact O-N 3.04Å; I519-V596 HydrophobicContact CD1-CB 4.35Å; I519-V596 HydrophobicContact CD1-CG1 3.74Å; I519-V596 HydrophobicContact CG1-CG1 4.29Å; I519-I599 HydrophobicContact CB-CG2 4.25Å; I519-I599 HydrophobicContact CD1-CB 4.23Å; I519-I599 HydrophobicContact CD1-CD1 4.35Å; I519-I599 HydrophobicContact CD1-CG2 4.03Å; I519-I599 HydrophobicContact CG2-CB 4.45Å; I519-I599 HydrophobicContact CG2-CG2 3.88Å; I519-N600 HydrophobicContact CG2-CB 3.87Å
520Q98Very high92.3Very high14 Ų1438.9 Ų38.97%0.06523%0.226CC..EExtended strand (participates in β ladder)trans-122137.5-173.8-178.7-179.9-15.200111F510 H511 R512 I518 F569 F570F510-Q520 CarbonylContact C-O 3.55Å; F510-Q520 VanDerWaalsContact CA-O 3.27Å; F510-Q520 WeakPolarHBondContact CA-O 3.29Å; H511-Q520 PolarHBondContact N-O 2.82Å; R512-Q520 HydrophobicContact CB-CB 4.19Å; R512-Q520 WeakPolarHBondContact O-CB 3.25Å; R512-Q520 PolarHBondContact O-N 3.02Å; I518-Q520 HydrophobicContact CD1-CB 4.49Å; Q520-F569 WeakPolarHBondContact CA-O 3.44Å; Q520-F570 HydrophobicContact CB-CB 3.98Å; Q520-F570 HydrophobicContact CG-CB 4.29Å
521T97.8Very high91.8Very high0 Ų040.3 Ų40.30%024%0.242CC..EExtended strand (participates in β ladder)trans-149.1-168.3-177.1-170.30000110.4V509 F510 Q568 F569 I617V509-T521 PolarHBondContact O-OG1 2.91Å; F510-T521 HydrophobicContact CD1-CG2 4.1Å; F510-T521 HydrophobicContact CE1-CG2 3.75Å; F510-T521 HydrophobicContact CZ-CG2 4.22Å; T521-Q568 WeakPolarHBondContact O-CA 3.34Å; T521-F569 HydrophobicContact CG2-CD1 4.35Å; T521-F569 HydrophobicContact CG2-CD2 4.46Å; T521-F569 HydrophobicContact CG2-CE1 3.75Å; T521-F569 HydrophobicContact CG2-CE2 3.88Å; T521-F569 HydrophobicContact CG2-CZ 3.48Å; T521-F569 VanDerWaalsContact CG2-CZ 3.48Å; T521-F569 PolarHBondContact N-O 2.96Å; T521-F569 PolarHBondContact O-N 2.84Å; T521-F569 VanDerWaalsContact O-N 3.09Å; T521-I617 HydrophobicContact CG2-CD1 3.94Å
522G96.1Very high91.5Very high0 Ų041.7 Ų41.70%026%0.255CS..  trans93.87.8174.200000115S567G522-S567 WeakPolarHBondContact O-CB 3.27Å; G522-S567 PolarHBondContact O-OG 2.94Å
523D93.9Very high91.4Very high0 Ų037 Ų370%024%0.238CC..  trans-101.9112.9172.6-179.1-5.6000110.2T525 G526 S527 G528 T529 G530 Q568D523-T525 VanDerWaalsContact CG-OG1 3.24Å; D523-T525 PolarHBondContact O-N 2.89Å; D523-T525 WeakPolarHBondContact OD1-CB 3.28Å; D523-T525 PolarHBondContact OD1-N 2.86Å; D523-T525 PolarHBondContact OD1-OG1 2.92Å; D523-T525 PolarHBondContact OD2-OG1 2.83Å; D523-T525 VanDerWaalsContact OD2-OG1 3.11Å; D523-G526 PolarHBondContact O-N 2.79Å; D523-G526 PolarHBondContact OD1-N 3.16Å; D523-S527 PolarHBondContact OD2-N 2.84Å; D523-S527 PolarHBondContact OD2-OG 3.32Å; D523-G528 VanDerWaalsContact OD2-CA 3.31Å; D523-G528 WeakPolarHBondContact OD2-CA 3.33Å; D523-G528 PolarHBondContact OD2-N 2.78Å; D523-T529 PolarHBondContact OD2-N 2.86Å; D523-G530 VanDerWaalsContact CG-C 3.46Å; D523-G530 WeakPolarHBondContact OD1-CA 3.29Å; D523-G530 PolarHBondContact OD2-N 2.74Å; D523-Q568 HydrophobicContact CB-CG 3.95Å
524P86.9Confident90.9Very high64 Ų6440 Ų4042%0.41625%0.253SS..THydrogen-bonded Turntrans-64-23.5177.7-21.532.8000114.8Y504 N508 G526Y504-P524 HydrophobicContact CD1-CG 4.18Å; Y504-P524 HydrophobicContact CE1-CG 3.42Å; Y504-P524 VanDerWaalsContact CE1-CG 3.42Å; Y504-P524 HydrophobicContact CE2-CG 4.03Å; Y504-P524 WeakPolarHBondContact OH-CG 3.26Å; N508-P524 WeakPolarHBondContact OD1-CA 3.38Å; P524-G526 VanDerWaalsContact C-N 3.3Å
525T86.2Confident90.6Very high97 Ų9742.7 Ų42.760%0.59526%0.261SS*.THydrogen-bonded Turntrans-81.8-18174.772.40000111.7D523 S527D523-T525 VanDerWaalsContact CG-OG1 3.24Å; D523-T525 PolarHBondContact O-N 2.89Å; D523-T525 WeakPolarHBondContact OD1-CB 3.28Å; D523-T525 PolarHBondContact OD1-N 2.86Å; D523-T525 PolarHBondContact OD1-OG1 2.92Å; D523-T525 PolarHBondContact OD2-OG1 2.83Å; D523-T525 VanDerWaalsContact OD2-OG1 3.11Å; T525-S527 PolarHBondContact O-N 3.45Å; T525-S527 PolarHBondContact OG1-N 2.84Å; T525-S527 PolarHBondContact OG1-OG 3.48Å; T525-S527 VanDerWaalsContact OG1-OG 3.06Å
526G86.8Confident90.2Very high4 Ų440.6 Ų40.64%0.04127%0.27CS..SBendtrans64.310.5-174.700000114.5H511 D523 P524 R610H511-G526 VanDerWaalsContact CB-O 3.26Å; H511-G526 WeakPolarHBondContact CB-O 3.34Å; D523-G526 PolarHBondContact O-N 2.79Å; D523-G526 PolarHBondContact OD1-N 3.16Å; P524-G526 VanDerWaalsContact C-N 3.3Å; G526-R610 PolarHBondContact O-NH1 3.07Å
527S86.5Confident89.9Confident69 Ų6942.1 Ų42.148%0.48327%0.268SS..SBendtrans-79.9-21.2-17969.30000113.1D523 T525 T529D523-S527 PolarHBondContact OD2-N 2.84Å; D523-S527 PolarHBondContact OD2-OG 3.32Å; T525-S527 PolarHBondContact O-N 3.45Å; T525-S527 PolarHBondContact OG1-N 2.84Å; T525-S527 PolarHBondContact OG1-OG 3.48Å; T525-S527 VanDerWaalsContact OG1-OG 3.06Å; S527-T529 VanDerWaalsContact C-N 3.32Å; S527-T529 PolarHBondContact OG-N 2.74Å; S527-T529 PolarHBondContact OG-OG1 3.19Å
528G85.8Confident89.5Confident26 Ų2644.3 Ų44.327%0.26828%0.282SS..SBendtrans86.4-1-167.900000113.7H511 D523 Q568H511-G528 VanDerWaalsContact CD2-CA 3.41Å; H511-G528 WeakPolarHBondContact CD2-CA 3.36Å; H511-G528 WeakPolarHBondContact NE2-CA 3.34Å; D523-G528 VanDerWaalsContact OD2-CA 3.31Å; D523-G528 WeakPolarHBondContact OD2-CA 3.33Å; D523-G528 PolarHBondContact OD2-N 2.78Å; G528-Q568 VanDerWaalsContact C-NE2 3.29Å; G528-Q568 PolarHBondContact O-NE2 3.04Å
529T84.3Confident89.1Confident131 Ų13144.4 Ų44.480%0.80428%0.282SS*.SBendtrans-117.7-6.2-179.665.90000113D523 S527D523-T529 PolarHBondContact OD2-N 2.86Å; S527-T529 VanDerWaalsContact C-N 3.32Å; S527-T529 PolarHBondContact OG-N 2.74Å; S527-T529 PolarHBondContact OG-OG1 3.19Å
530G83.9Confident88.7Confident17 Ų1748 Ų4818%0.17530%0.299CS..  trans-96.6-174.7176.900000112.5D523 Q568D523-G530 VanDerWaalsContact CG-C 3.46Å; D523-G530 WeakPolarHBondContact OD1-CA 3.29Å; D523-G530 PolarHBondContact OD2-N 2.74Å; G530-Q568 PolarHBondContact O-NE2 3.32Å
531G85.8Confident88.4Confident34 Ų3448.4 Ų48.435%0.35130%0.301SS..  trans101.5137.3-176.500000112.3Y504 S567Y504-G531 WeakPolarHBondContact OH-CA 3.46Å; G531-S567 WeakPolarHBondContact CA-OG 3.22Å
532A89.2Confident88Confident39 Ų3949.7 Ų49.732%0.32231%0.308SS..  trans-136.1149.3179.900000108.9Y504 S567Y504-A532 PolarHBondContact OH-N 2.86Å; Y504-A532 PolarHBondContact OH-O 3.27Å; A532-S567 PolarHBondContact N-OG 2.8Å; A532-S567 WeakPolarHBondContact O-CB 3.36Å
533S92.6Very high87.7Confident6 Ų654.4 Ų54.44%0.04233%0.328CS..  trans-65.1168.1171.680.20000111N495 W535 G536 H537N495-S533 VanDerWaalsContact OD1-CA 3.25Å; N495-S533 WeakPolarHBondContact OD1-CA 3.17Å; N495-S533 WeakPolarHBondContact OD1-CB 3.38Å; S533-W535 PolarHBondContact O-N 2.91Å; S533-W535 VanDerWaalsContact O-N 3.12Å; S533-W535 PolarHBondContact OG-N 3.49Å; S533-W535 VanDerWaalsContact OG-N 3.13Å; S533-G536 PolarHBondContact O-N 2.68Å; S533-G536 PolarHBondContact OG-N 3.5Å; S533-H537 WeakPolarHBondContact CB-O 3.49Å; S533-H537 PolarHBondContact OG-O 3.4Å
534M87.2Confident87.5Confident65 Ų6558.3 Ų58.332%0.3235%0.346SS..THydrogen-bonded Turntrans-59.5-21.1172.667.4172.6-78.200113.6E494 N495 T498 L499E494-M534 HydrophobicContact CG-SD 4.01Å; N495-M534 HydrophobicContact CB-CG 4.4Å; N495-M534 PolarHBondContact OD1-N 3.02Å; T498-M534 HydrophobicContact CG2-CB 4.46Å; T498-M534 HydrophobicContact CG2-CE 3.79Å; T498-M534 HydrophobicContact CG2-SD 3.99Å; L499-M534 HydrophobicContact CD2-CB 4.14Å; L499-M534 HydrophobicContact CG-CB 4.22Å
535W86.7Confident87.3Confident90 Ų9060.5 Ų60.534%0.34136%0.361SS..THydrogen-bonded Turntrans-90.7-3179.4-55.1-73.2000113.1K491 N495 S533 H537 F539K491-W535 HydrophobicContact CB-CH2 4.1Å; K491-W535 WeakPolarHBondContact O-CH2 3.48Å; N495-W535 HydrophobicContact CB-CH2 3.87Å; N495-W535 HydrophobicContact CB-CZ3 3.75Å; S533-W535 PolarHBondContact O-N 2.91Å; S533-W535 VanDerWaalsContact O-N 3.12Å; S533-W535 PolarHBondContact OG-N 3.49Å; S533-W535 VanDerWaalsContact OG-N 3.13Å; W535-H537 PolarHBondContact O-N 2.97Å; W535-F539 HydrophobicContact CE3-CB 4.09Å; W535-F539 HydrophobicContact CE3-CD1 4.06Å; W535-F539 HydrophobicContact CE3-CG 4.16Å; W535-F539 HydrophobicContact CZ3-CB 3.94Å; W535-F539 AromaticContact CZ3-CD1 3.69Å; W535-F539 HydrophobicContact CZ3-CD1 3.69Å; W535-F539 HydrophobicContact CZ3-CD2 4.1Å; W535-F539 HydrophobicContact CZ3-CE1 4.18Å; W535-F539 AromaticContact CZ3-CG 3.64Å; W535-F539 HydrophobicContact CZ3-CG 3.64Å
536G84.3Confident87.3Confident63 Ų6358.8 Ų58.865%0.64936%0.362SS*.SBendtrans76.15.117900000115.1S533S533-G536 PolarHBondContact O-N 2.68Å; S533-G536 PolarHBondContact OG-N 3.5Å
537H85.9Confident87.6Confident112 Ų11260 Ų6052%0.51937%0.368SS..SBendtrans-141.8165.8174.558.544.7000110.7S533 W535S533-H537 WeakPolarHBondContact CB-O 3.49Å; S533-H537 PolarHBondContact OG-O 3.4Å; W535-H537 PolarHBondContact O-N 2.97Å
538D86.9Confident88Confident93 Ų9362.3 Ų62.350%0.49737%0.369SS..  trans-57.5151.3174.3-70.5-4.8000112.5T564 N565D538-T564 WeakPolarHBondContact OD2-CB 3.29Å; D538-T564 WeakPolarHBondContact OD2-CG2 3.25Å; D538-N565 WeakPolarHBondContact CA-O 3.2Å
539F88.4Confident88.4Confident8 Ų861 Ų614%0.03536%0.356CS..BIsolated β-bridgetrans-131.7164.8174.772.7-85.8000113T492 N495 W535 M557 N563 N565 G566T492-F539 HydrophobicContact CG2-CZ 4.41Å; N495-F539 HydrophobicContact CB-CE1 4.12Å; N495-F539 HydrophobicContact CB-CZ 4.09Å; N495-F539 WeakPolarHBondContact ND2-CE1 3.33Å; W535-F539 HydrophobicContact CE3-CB 4.09Å; W535-F539 HydrophobicContact CE3-CD1 4.06Å; W535-F539 HydrophobicContact CE3-CG 4.16Å; W535-F539 HydrophobicContact CZ3-CB 3.94Å; W535-F539 AromaticContact CZ3-CD1 3.69Å; W535-F539 HydrophobicContact CZ3-CD1 3.69Å; W535-F539 HydrophobicContact CZ3-CD2 4.1Å; W535-F539 HydrophobicContact CZ3-CE1 4.18Å; W535-F539 AromaticContact CZ3-CG 3.64Å; W535-F539 HydrophobicContact CZ3-CG 3.64Å; F539-M557 HydrophobicContact CE1-CE 4.36Å; F539-M557 HydrophobicContact CZ-CE 4.14Å; F539-N563 CarbonylContact O-C 3.55Å; F539-N565 HydrophobicContact CD1-CB 3.74Å; F539-N565 WeakPolarHBondContact CD1-O 3.16Å; F539-N565 HydrophobicContact CD2-CB 4.07Å; F539-N565 HydrophobicContact CE1-CB 3.41Å; F539-N565 VanDerWaalsContact CE1-CB 3.41Å; F539-N565 WeakPolarHBondContact CE1-O 3.44Å; F539-N565 HydrophobicContact CE2-CB 3.76Å; F539-N565 HydrophobicContact CG-CB 4.06Å; F539-N565 HydrophobicContact CZ-CB 3.42Å; F539-N565 VanDerWaalsContact CZ-CB 3.42Å; F539-N565 PolarHBondContact N-O 2.93Å; F539-N565 VanDerWaalsContact N-O 3.1Å; F539-N565 WeakPolarHBondContact O-CB 3.41Å; F539-N565 PolarHBondContact O-N 3.21Å; F539-N565 PolarHBondContact O-ND2 2.87Å; F539-G566 WeakPolarHBondContact CE1-O 3.49Å
540E90.6Very high88.8Confident77 Ų7758.8 Ų58.836%0.3634%0.339SS..  trans-67.1160.2-170.468.1-99.7-127.100114.9K491 N563 N565K491-E540 HydrophobicContact CD-CG 4.46Å; K491-E540 WeakPolarHBondContact CD-OE1 3.28Å; K491-E540 WeakPolarHBondContact CE-OE1 3.1Å; K491-E540 IonicContact NZ-OE1 3.27Å; K491-E540 PolarHBondContact NZ-OE1 3.43Å; K491-E540 IonicContact NZ-OE2 3.54Å; K491-E540 PolarHBondContact NZ-OE2 2.96Å; K491-E540 VanDerWaalsContact NZ-OE2 3.08Å; E540-N563 WeakPolarHBondContact CA-OD1 3.17Å; E540-N563 HydrophobicContact CB-CB 4.49Å; E540-N563 WeakPolarHBondContact CB-OD1 3.31Å; E540-N565 PolarHBondContact O-ND2 2.87Å
541D90Very high89.2Confident21 Ų2164.1 Ų64.111%0.11235%0.354CS..  trans-80.5140.1170.3-64.4-51.1000111.9F543 N559 P562 N563 N565 T584D541-F543 HydrophobicContact CB-CD1 4.27Å; D541-F543 HydrophobicContact CB-CD2 4.36Å; D541-F543 HydrophobicContact CB-CE1 3.62Å; D541-F543 HydrophobicContact CB-CE2 3.72Å; D541-F543 HydrophobicContact CB-CZ 3.3Å; D541-N559 PolarHBondContact OD1-ND2 3.36Å; D541-P562 WeakPolarHBondContact OD2-CA 3.29Å; D541-N563 PolarHBondContact N-OD1 3.16Å; D541-N563 PolarHBondContact OD2-N 3.46Å; D541-N565 PolarHBondContact OD1-ND2 2.78Å; D541-T584 WeakPolarHBondContact CA-OG1 3.35Å
542E90.6Very high89.7Confident28 Ų2864.5 Ų64.513%0.13135%0.351CS..  trans-115.778.9179.1-64.9177.3122.100110.6C489 P490 K491 T492 H544 T584C489-E542 WeakPolarHBondContact CA-OE2 3.37Å; C489-E542 HydrophobicContact CB-CB 4.04Å; C489-E542 WeakPolarHBondContact CB-OE2 3.31Å; C489-E542 PolarHBondContact SG-O 3.27Å; C489-E542 VanDerWaalsContact SG-O 3.33Å; P490-E542 WeakPolarHBondContact CD-OE1 3.24Å; P490-E542 WeakPolarHBondContact CG-OE1 3.15Å; K491-E542 WeakPolarHBondContact CB-OE1 3.46Å; K491-E542 PolarHBondContact N-OE1 2.9Å; K491-E542 PolarHBondContact N-OE2 3.36Å; T492-E542 VanDerWaalsContact CB-OE2 3.29Å; T492-E542 WeakPolarHBondContact CB-OE2 3.37Å; T492-E542 PolarHBondContact N-OE2 3.42Å; T492-E542 PolarHBondContact OG1-OE2 3.32Å; E542-H544 PolarHBondContact O-N 3.45Å; E542-T584 HydrophobicContact CB-CG2 3.86Å; E542-T584 PolarHBondContact N-OG1 3.26Å
543F89.6Confident90.1Very high98 Ų9864 Ų6443%0.4334%0.341SS..  trans-82.2116.5-179.4-53.7-45000112.2D541 K581D541-F543 HydrophobicContact CB-CD1 4.27Å; D541-F543 HydrophobicContact CB-CD2 4.36Å; D541-F543 HydrophobicContact CB-CE1 3.62Å; D541-F543 HydrophobicContact CB-CE2 3.72Å; D541-F543 HydrophobicContact CB-CZ 3.3Å; F543-K581 HydrophobicContact CD2-CB 4.49Å; F543-K581 WeakPolarHBondContact CE2-O 3.09Å; F543-K581 WeakPolarHBondContact CZ-O 3.39Å
544H89Confident90.3Very high82 Ų8264 Ų6438%0.3834%0.34SS..  trans-104.4133.2174.6-167-97.4000111.9E488 E542 G546 L547E488-H544 HydrophobicContact CB-CB 4.03Å; E488-H544 HydrophobicContact CG-CB 4.45Å; E542-H544 PolarHBondContact O-N 3.45Å; H544-G546 PolarHBondContact ND1-N 3.01Å; H544-G546 PolarHBondContact O-N 3.11Å; H544-L547 HydrophobicContact CB-CB 4.35Å; H544-L547 HydrophobicContact CB-CD1 3.95Å; H544-L547 HydrophobicContact CB-CG 4Å; H544-L547 PolarHBondContact O-N 3.03Å
545P83.1Confident90.9Very high111 Ų11160.9 Ų60.972%0.72133%0.325SS*.THydrogen-bonded Turntrans-57.6-27.8-176-2633.7000115.3
546G86.8Confident91.4Very high61 Ų6156.6 Ų56.663%0.62931%0.309SS*.THydrogen-bonded Turntrans-84.8-10.817900000114.9H544H544-G546 PolarHBondContact ND1-N 3.01Å; H544-G546 PolarHBondContact O-N 3.11Å
547L93.2Very high92Very high30 Ų3053.6 Ų53.616%0.15728%0.278CS..  trans-103.4117.8-178.6-60.1-178.1000109.5Y485 E488 H544 I585Y485-L547 HydrophobicContact CD2-CD1 3.69Å; Y485-L547 HydrophobicContact CD2-CD2 3.69Å; Y485-L547 HydrophobicContact CD2-CG 4.36Å; Y485-L547 HydrophobicContact CE2-CD1 4.36Å; Y485-L547 HydrophobicContact CE2-CD2 3.59Å; Y485-L547 HydrophobicContact CG-CD1 4.23Å; Y485-L547 HydrophobicContact CG-CD2 4.27Å; E488-L547 HydrophobicContact CB-CD1 3.81Å; E488-L547 HydrophobicContact CG-CD1 4.29Å; H544-L547 HydrophobicContact CB-CB 4.35Å; H544-L547 HydrophobicContact CB-CD1 3.95Å; H544-L547 HydrophobicContact CB-CG 4Å; H544-L547 PolarHBondContact O-N 3.03Å; L547-I585 HydrophobicContact CB-CB 4.06Å; L547-I585 HydrophobicContact CB-CD1 4.18Å; L547-I585 HydrophobicContact CB-CG2 4.11Å; L547-I585 HydrophobicContact CD1-CB 4.48Å; L547-I585 HydrophobicContact CD1-CG2 4.35Å; L547-I585 WeakPolarHBondContact CD1-O 3.23Å
548K93.4Very high92.4Very high116 Ų11649 Ų4950%0.50426%0.259SS..  trans-139.6152.7-178.1-61.6-176.3-177177.60110.8D550 I585K548-D550 HydrophobicContact CB-CB 4.22Å; K548-D550 PolarHBondContact O-N 2.87Å; K548-I585 VanDerWaalsContact CA-CD1 3.46Å
549H95.6Very high92.6Very high0 Ų046 Ų460%024%0.243CC..SBendtrans-79.146.6172.5-58.888.9000111S556 P575 A576 A577 D580 I585H549-S556 VanDerWaalsContact NE2-CB 3.35Å; H549-S556 WeakPolarHBondContact NE2-CB 3.26Å; H549-S556 PolarHBondContact NE2-OG 3.26Å; H549-P575 CarbonylContact O-C 3.53Å; H549-P575 WeakPolarHBondContact O-CA 3.4Å; H549-A576 HydrophobicContact CB-CB 4.11Å; H549-A576 WeakPolarHBondContact CB-O 3.45Å; H549-A576 PolarHBondContact O-N 3.34Å; H549-A577 PolarHBondContact O-N 3.2Å; H549-D580 IonicContact CE1-OD1 3.65Å; H549-D580 IonicContact CG-OD1 3.89Å; H549-D580 PolarHBondContact N-OD1 3.29Å; H549-D580 IonicContact ND1-OD1 3.48Å; H549-D580 PolarHBondContact ND1-OD1 3.26Å; H549-I585 VanDerWaalsContact CE1-CG1 3.45Å; H549-I585 WeakPolarHBondContact CE1-CG1 3.45Å
550D92.2Very high92.3Very high84 Ų8451.9 Ų51.945%0.44928%0.284SS..  trans-85.1-8.6-17370.7-16000113.8K548K548-D550 HydrophobicContact CB-CB 4.22Å; K548-D550 PolarHBondContact O-N 2.87Å
551R92.9Very high91.9Very high128 Ų12849.4 Ų49.448%0.48328%0.279SS..SBendtrans-144.6161.2-174.168.9-169.371.7-166.6-1.6111V554 T572 L588R551-V554 HydrophobicContact CG-CG2 3.84Å; R551-V554 WeakPolarHBondContact O-CG2 3.17Å; R551-T572 PolarHBondContact O-OG1 3.11Å; R551-L588 HydrophobicContact CG-CD1 4.34Å
552P95.4Very high91.6Very high43 Ų4353.5 Ų53.528%0.27931%0.307SS..THydrogen-bonded Turntrans-65.5164169.230.8-37.8000111.7V554 V573P552-V554 VanDerWaalsContact C-N 3.34Å; P552-V554 PolarHBondContact O-N 3.45Å; P552-V573 WeakPolarHBondContact CB-O 3.38Å
553F97.5Very high91.4Very high28 Ų2856.2 Ų56.212%0.12332%0.323CS..THydrogen-bonded Turntrans71.120.8172.8-39.4-65.3000116.4T572 L588 V589 M593 V596 Q597F553-T572 WeakPolarHBondContact CA-O 3.29Å; F553-T572 PolarHBondContact N-O 3.1Å; F553-T572 PolarHBondContact N-OG1 2.93Å; F553-L588 WeakPolarHBondContact O-CD1 3.25Å; F553-V589 HydrophobicContact CB-CB 3.87Å; F553-V589 HydrophobicContact CB-CG2 4.22Å; F553-V589 PolarHBondContact O-N 2.77Å; F553-M593 HydrophobicContact CD1-CB 4.31Å; F553-M593 HydrophobicContact CD1-CG 4.23Å; F553-M593 HydrophobicContact CD2-CB 4.43Å; F553-M593 HydrophobicContact CD2-CG 3.78Å; F553-M593 HydrophobicContact CE1-CB 3.84Å; F553-M593 HydrophobicContact CE1-CG 4.18Å; F553-M593 HydrophobicContact CE2-CB 3.98Å; F553-M593 HydrophobicContact CE2-CG 3.72Å; F553-M593 HydrophobicContact CG-CG 4.04Å; F553-M593 HydrophobicContact CZ-CB 3.66Å; F553-M593 HydrophobicContact CZ-CG 3.92Å; F553-V596 HydrophobicContact CD1-CB 4.26Å; F553-V596 HydrophobicContact CD1-CG1 3.99Å; F553-V596 HydrophobicContact CE1-CB 4.37Å; F553-V596 HydrophobicContact CE1-CG1 4.28Å; F553-Q597 HydrophobicContact CE1-CG 4.13Å; F553-Q597 HydrophobicContact CZ-CG 4.33Å
554V97.7Very high91.4Very high5 Ų553.2 Ų53.23%0.0331%0.312CS..EExtended strand (participates in β ladder)trans-78.2131.4173.9178.50000109.3R551 P552 I571 T572 I585 L588R551-V554 HydrophobicContact CG-CG2 3.84Å; R551-V554 WeakPolarHBondContact O-CG2 3.17Å; P552-V554 VanDerWaalsContact C-N 3.34Å; P552-V554 PolarHBondContact O-N 3.45Å; V554-I571 WeakPolarHBondContact O-CA 3.44Å; V554-T572 HydrophobicContact CB-CG2 4.44Å; V554-T572 PolarHBondContact N-OG1 3.21Å; V554-T572 PolarHBondContact O-N 3.31Å; V554-I585 HydrophobicContact CG1-CB 4.2Å; V554-I585 HydrophobicContact CG1-CD1 4Å; V554-I585 HydrophobicContact CG1-CG1 3.75Å; V554-I585 HydrophobicContact CG1-CG2 3.47Å; V554-I585 VanDerWaalsContact CG1-CG2 3.47Å; V554-L588 HydrophobicContact CG2-CD1 3.97Å
555M98.3Very high91.6Very high0 Ų049.3 Ų49.30%029%0.294CS..EExtended strand (participates in β ladder)trans-91.3127.4172.6-59.3177.566.400109.8I473 C482 F496 F569 F570 I571 I585 F586 G587I473-M555 HydrophobicContact CD1-CE 4.12Å; C482-M555 HydrophobicContact CB-SD 3.46Å; C482-M555 WeakPolarHBondContact CB-SD 3.43Å; C482-M555 PolarHBondContact SG-SD 3.46Å; F496-M555 HydrophobicContact CE2-CE 4.39Å; F496-M555 HydrophobicContact CZ-CE 4.2Å; M555-F569 HydrophobicContact CE-CD2 4.13Å; M555-F569 HydrophobicContact CE-CE2 3.86Å; M555-F570 WeakPolarHBondContact CA-O 3.29Å; M555-I571 HydrophobicContact CG-CG1 4.2Å; M555-I585 WeakPolarHBondContact O-CA 3.4Å; M555-F586 HydrophobicContact CB-CE1 4.19Å; M555-F586 HydrophobicContact CB-CZ 4.2Å; M555-F586 HydrophobicContact CE-CE2 3.72Å; M555-F586 HydrophobicContact CE-CZ 3.73Å; M555-F586 PolarHBondContact O-N 3.49Å; M555-F586 VanDerWaalsContact O-N 3.07Å; M555-G587 PolarHBondContact N-O 2.73Å
556S97.7Very high92.1Very high0 Ų044.5 Ų44.50%026%0.264CS..EExtended strand (participates in β ladder)trans-143.1146.9-178.6-178.10000112.3H549 F569 F570 H583 T584H549-S556 VanDerWaalsContact NE2-CB 3.35Å; H549-S556 WeakPolarHBondContact NE2-CB 3.26Å; H549-S556 PolarHBondContact NE2-OG 3.26Å; S556-F569 CarbonylContact O-C 3.57Å; S556-F569 VanDerWaalsContact O-CA 3.3Å; S556-F569 WeakPolarHBondContact O-CA 3.43Å; S556-F569 WeakPolarHBondContact O-CB 3.5Å; S556-F570 PolarHBondContact N-O 2.74Å; S556-F570 PolarHBondContact O-N 2.96Å; S556-H583 WeakPolarHBondContact OG-CB 3.49Å; S556-T584 CarbonylContact C-O 3.59Å; S556-T584 VanDerWaalsContact CA-O 3.23Å; S556-T584 WeakPolarHBondContact CA-O 3.49Å; S556-T584 PolarHBondContact OG-O 3.46Å
557M97.7Very high92.6Very high1 Ų141.6 Ų41.61%0.00523%0.234CC..EExtended strand (participates in β ladder)trans-66.5140178.2-67.4-57-64.900111.8T492 F539 N565 G566 Q568 F569 F570 H583 T584 F586T492-M557 HydrophobicContact CG2-CG 3.45Å; T492-M557 VanDerWaalsContact CG2-CG 3.45Å; T492-M557 HydrophobicContact CG2-SD 3.69Å; F539-M557 HydrophobicContact CE1-CE 4.36Å; F539-M557 HydrophobicContact CZ-CE 4.14Å; M557-N565 VanDerWaalsContact CB-OD1 3.22Å; M557-N565 WeakPolarHBondContact CB-OD1 3.3Å; M557-N565 HydrophobicContact CE-CB 4.23Å; M557-G566 WeakPolarHBondContact CE-O 3.45Å; M557-Q568 WeakPolarHBondContact CE-O 3.46Å; M557-F569 HydrophobicContact SD-CB 4.27Å; M557-F570 WeakPolarHBondContact O-CE1 3.43Å; M557-H583 WeakPolarHBondContact O-CB 3.27Å; M557-H583 PolarHBondContact O-ND1 2.88Å; M557-H583 VanDerWaalsContact O-ND1 3.16Å; M557-T584 PolarHBondContact N-O 3.33Å; M557-F586 HydrophobicContact CG-CD1 4.05Å; M557-F586 HydrophobicContact CG-CE1 4.2Å; M557-F586 HydrophobicContact SD-CD1 4.02Å; M557-F586 HydrophobicContact SD-CE1 3.68Å; M557-F586 HydrophobicContact SD-CZ 4.32Å
558A93.7Very high92.8Very high15 Ų1541.1 Ų41.112%0.12423%0.231CC..EExtended strand (participates in β ladder)trans-92.5125.1166.900000108.6Q568 F570A558-Q568 HydrophobicContact CB-CB 3.81Å; A558-Q568 PolarHBondContact N-O 2.82Å; A558-F570 HydrophobicContact CB-CD1 4.14Å
559N90.8Very high93.1Very high29 Ų2935.6 Ų35.616%0.15521%0.208CC..EExtended strand (participates in β ladder)trans-130.9164.4179.563.630.7000110.4D541 G561 T564 K582 H583D541-N559 PolarHBondContact OD1-ND2 3.36Å; N559-G561 VanDerWaalsContact C-N 3.32Å; N559-G561 VanDerWaalsContact CG-O 3.3Å; N559-G561 PolarHBondContact OD1-N 2.98Å; N559-G561 PolarHBondContact OD1-O 3.19Å; N559-T564 WeakPolarHBondContact CB-O 3.37Å; N559-K582 PolarHBondContact ND2-O 3.49Å; N559-H583 PolarHBondContact OD1-CE1 3.23Å; N559-H583 PolarHBondContact OD1-ND1 2.84Å
560C82Confident93.2Very high133 Ų13336 Ų3690%0.89921%0.209SC*.SBendtrans-9513.4177.6-67.70000112.4T564C560-T564 WeakPolarHBondContact CA-OG1 3.39Å; C560-T564 PolarHBondContact N-OG1 3.3Å
561G82.3Confident93.5Very high25 Ų2532.1 Ų32.126%0.25819%0.188SC..SBendtrans138.7178.9-16900000111.5N559 N563 T564N559-G561 VanDerWaalsContact C-N 3.32Å; N559-G561 VanDerWaalsContact CG-O 3.3Å; N559-G561 PolarHBondContact OD1-N 2.98Å; N559-G561 PolarHBondContact OD1-O 3.19Å; G561-N563 PolarHBondContact O-N 3.44Å; G561-T564 PolarHBondContact N-OG1 3.29Å; G561-T564 VanDerWaalsContact N-OG1 3.07Å; G561-T564 PolarHBondContact O-N 3.43Å; G561-T564 PolarHBondContact O-OG1 3.47Å
562P84.6Confident93.7Very high106 Ų10626 Ų2669%0.68817%0.165SC*.THydrogen-bonded Turntrans-54.6133.6-178.9-25.134.3000112.4D541 T564D541-P562 WeakPolarHBondContact OD2-CA 3.29Å; P562-T564 VanDerWaalsContact C-N 3.28Å; P562-T564 PolarHBondContact O-N 2.87Å
563N85.4Confident93.7Very high86 Ų8624.9 Ų24.946%0.4616%0.158SC..THydrogen-bonded Turntrans58.431.7176.5-51.8-50.2000115F539 E540 D541 G561F539-N563 CarbonylContact O-C 3.55Å; E540-N563 WeakPolarHBondContact CA-OD1 3.17Å; E540-N563 HydrophobicContact CB-CB 4.49Å; E540-N563 WeakPolarHBondContact CB-OD1 3.31Å; D541-N563 PolarHBondContact N-OD1 3.16Å; D541-N563 PolarHBondContact OD2-N 3.46Å; G561-N563 PolarHBondContact O-N 3.44Å
564T90.6Very high93.5Very high35 Ų3525.7 Ų25.722%0.21517%0.165CC..  trans-114.141.2176.859.30000112D538 N559 C560 G561 P562D538-T564 WeakPolarHBondContact OD2-CB 3.29Å; D538-T564 WeakPolarHBondContact OD2-CG2 3.25Å; N559-T564 WeakPolarHBondContact CB-O 3.37Å; C560-T564 WeakPolarHBondContact CA-OG1 3.39Å; C560-T564 PolarHBondContact N-OG1 3.3Å; G561-T564 PolarHBondContact N-OG1 3.29Å; G561-T564 VanDerWaalsContact N-OG1 3.07Å; G561-T564 PolarHBondContact O-N 3.43Å; G561-T564 PolarHBondContact O-OG1 3.47Å; P562-T564 VanDerWaalsContact C-N 3.28Å; P562-T564 PolarHBondContact O-N 2.87Å
565N93.7Very high93.3Very high0 Ų029.4 Ų29.40%019%0.189CC..EExtended strand (participates in β ladder)trans-77130.1179.9-65.8-54.1000110.5D538 F539 E540 D541 M557D538-N565 WeakPolarHBondContact CA-O 3.2Å; F539-N565 HydrophobicContact CD1-CB 3.74Å; F539-N565 WeakPolarHBondContact CD1-O 3.16Å; F539-N565 HydrophobicContact CD2-CB 4.07Å; F539-N565 HydrophobicContact CE1-CB 3.41Å; F539-N565 VanDerWaalsContact CE1-CB 3.41Å; F539-N565 WeakPolarHBondContact CE1-O 3.44Å; F539-N565 HydrophobicContact CE2-CB 3.76Å; F539-N565 HydrophobicContact CG-CB 4.06Å; F539-N565 HydrophobicContact CZ-CB 3.42Å; F539-N565 VanDerWaalsContact CZ-CB 3.42Å; F539-N565 PolarHBondContact N-O 2.93Å; F539-N565 VanDerWaalsContact N-O 3.1Å; F539-N565 WeakPolarHBondContact O-CB 3.41Å; F539-N565 PolarHBondContact O-N 3.21Å; F539-N565 PolarHBondContact O-ND2 2.87Å; E540-N565 PolarHBondContact O-ND2 2.87Å; D541-N565 PolarHBondContact OD1-ND2 2.78Å; M557-N565 VanDerWaalsContact CB-OD1 3.22Å; M557-N565 WeakPolarHBondContact CB-OD1 3.3Å; M557-N565 HydrophobicContact CE-CB 4.23Å
566G93.7Very high93.1Very high9 Ų929.4 Ų29.49%0.09319%0.189CC..EExtended strand (participates in β ladder)trans-116-123.8174.400000111.5N495 F539 M557N495-G566 PolarHBondContact ND2-O 2.97Å; F539-G566 WeakPolarHBondContact CE1-O 3.49Å; M557-G566 WeakPolarHBondContact CE-O 3.45Å
567S96.1Very high92.7Very high0 Ų032.4 Ų32.40%021%0.214CC..EExtended strand (participates in β ladder)trans-104.3-15.7174.1580000114Y504 Y505 G522 G531 A532Y504-S567 VanDerWaalsContact CE1-CB 3.47Å; Y505-S567 WeakPolarHBondContact CE1-O 3.49Å; Y505-S567 PolarHBondContact OH-O 2.96Å; Y505-S567 VanDerWaalsContact OH-O 3.11Å; G522-S567 WeakPolarHBondContact O-CB 3.27Å; G522-S567 PolarHBondContact O-OG 2.94Å; G531-S567 WeakPolarHBondContact CA-OG 3.22Å; A532-S567 PolarHBondContact N-OG 2.8Å; A532-S567 WeakPolarHBondContact O-CB 3.36Å
568Q98.2Very high92.4Very high20 Ų2037.7 Ų37.79%0.09324%0.239CC..EExtended strand (participates in β ladder)trans-72.7140.1-175.4-66.4-167.54300111.8H511 T521 D523 G528 G530 M557 A558H511-Q568 PolarHBondContact NE2-OE1 3.09Å; T521-Q568 WeakPolarHBondContact O-CA 3.34Å; D523-Q568 HydrophobicContact CB-CG 3.95Å; G528-Q568 VanDerWaalsContact C-NE2 3.29Å; G528-Q568 PolarHBondContact O-NE2 3.04Å; G530-Q568 PolarHBondContact O-NE2 3.32Å; M557-Q568 WeakPolarHBondContact CE-O 3.46Å; A558-Q568 HydrophobicContact CB-CB 3.81Å; A558-Q568 PolarHBondContact N-O 2.82Å
569F98.3Very high92.3Very high1 Ų137.9 Ų37.90%0.00424%0.237CC..EExtended strand (participates in β ladder)trans-146.7162.8175.269.5-85.2000110.9I473 F496 Y505 Q520 T521 M555 S556 M557 I571 F586I473-F569 HydrophobicContact CD1-CE2 4.29Å; I473-F569 HydrophobicContact CD1-CZ 4.19Å; F496-F569 HydrophobicContact CD2-CD1 4.39Å; F496-F569 HydrophobicContact CD2-CE1 4.25Å; F496-F569 HydrophobicContact CE2-CD1 4.24Å; F496-F569 AromaticContact CE2-CE1 3.7Å; F496-F569 HydrophobicContact CE2-CE1 3.7Å; F496-F569 AromaticContact CE2-CZ 3.88Å; F496-F569 HydrophobicContact CE2-CZ 3.88Å; Y505-F569 HydrophobicContact CD1-CE1 4.36Å; Y505-F569 HydrophobicContact CE1-CD1 4.37Å; Y505-F569 HydrophobicContact CE1-CE1 4.03Å; Q520-F569 WeakPolarHBondContact CA-O 3.44Å; T521-F569 HydrophobicContact CG2-CD1 4.35Å; T521-F569 HydrophobicContact CG2-CD2 4.46Å; T521-F569 HydrophobicContact CG2-CE1 3.75Å; T521-F569 HydrophobicContact CG2-CE2 3.88Å; T521-F569 HydrophobicContact CG2-CZ 3.48Å; T521-F569 VanDerWaalsContact CG2-CZ 3.48Å; T521-F569 PolarHBondContact N-O 2.96Å; T521-F569 PolarHBondContact O-N 2.84Å; T521-F569 VanDerWaalsContact O-N 3.09Å; M555-F569 HydrophobicContact CE-CD2 4.13Å; M555-F569 HydrophobicContact CE-CE2 3.86Å; S556-F569 CarbonylContact O-C 3.57Å; S556-F569 VanDerWaalsContact O-CA 3.3Å; S556-F569 WeakPolarHBondContact O-CA 3.43Å; S556-F569 WeakPolarHBondContact O-CB 3.5Å; M557-F569 HydrophobicContact SD-CB 4.27Å; F569-I571 HydrophobicContact CE2-CG1 4.43Å; F569-F586 HydrophobicContact CB-CE1 3.87Å; F569-F586 HydrophobicContact CB-CZ 3.99Å; F569-F586 HydrophobicContact CD2-CZ 4.19Å; F569-F586 HydrophobicContact CG-CE1 4.4Å; F569-F586 HydrophobicContact CG-CZ 4.03Å
570F98.1Very high92.3Very high8 Ų838.6 Ų38.64%0.03524%0.241CC..EExtended strand (participates in β ladder)trans-131.3156.5175.760.6-96.4000112.2I518 I519 Q520 M555 S556 M557 A558 T572 L579 H583I518-F570 HydrophobicContact CB-CB 4.22Å; I518-F570 HydrophobicContact CB-CD2 4.24Å; I518-F570 HydrophobicContact CB-CG 4.48Å; I518-F570 HydrophobicContact CD1-CB 4.05Å; I518-F570 HydrophobicContact CD1-CD2 4.48Å; I518-F570 HydrophobicContact CD1-CG 4.13Å; I518-F570 HydrophobicContact CG2-CD2 3.67Å; I518-F570 HydrophobicContact CG2-CE2 4.21Å; I518-F570 HydrophobicContact CG2-CG 4.31Å; I519-F570 CarbonylContact O-C 3.57Å; I519-F570 WeakPolarHBondContact O-CA 3.31Å; I519-F570 VanDerWaalsContact O-CB 3.32Å; I519-F570 WeakPolarHBondContact O-CB 3.29Å; Q520-F570 HydrophobicContact CB-CB 3.98Å; Q520-F570 HydrophobicContact CG-CB 4.29Å; M555-F570 WeakPolarHBondContact CA-O 3.29Å; S556-F570 PolarHBondContact N-O 2.74Å; S556-F570 PolarHBondContact O-N 2.96Å; M557-F570 WeakPolarHBondContact O-CE1 3.43Å; A558-F570 HydrophobicContact CB-CD1 4.14Å; F570-T572 HydrophobicContact CD2-CG2 4.32Å; F570-T572 HydrophobicContact CE2-CG2 4.13Å; F570-L579 HydrophobicContact CE2-CD1 3.73Å; F570-L579 HydrophobicContact CZ-CD1 3.74Å; F570-H583 HydrophobicContact CE1-CB 4.32Å; F570-H583 HydrophobicContact CZ-CB 4.07Å
571I98.3Very high92.5Very high2 Ų240.5 Ų40.51%0.0123%0.234CC..EExtended strand (participates in β ladder)trans-113.3125.9172.4-51.1-177.6000107.9I480 I518 I519 V554 M555 F569 V589 V596I480-I571 HydrophobicContact CG2-CD1 4.42Å; I518-I571 VanDerWaalsContact CA-O 3.3Å; I518-I571 WeakPolarHBondContact CA-O 3.17Å; I519-I571 HydrophobicContact CD1-CB 4.33Å; I519-I571 HydrophobicContact CD1-CD1 4.39Å; I519-I571 HydrophobicContact CG1-CB 3.83Å; I519-I571 HydrophobicContact CG1-CG1 4.37Å; I519-I571 PolarHBondContact N-O 2.96Å; I519-I571 PolarHBondContact O-N 3.04Å; V554-I571 WeakPolarHBondContact O-CA 3.44Å; M555-I571 HydrophobicContact CG-CG1 4.2Å; F569-I571 HydrophobicContact CE2-CG1 4.43Å; I571-V589 HydrophobicContact CD1-CG2 4.1Å; I571-V589 HydrophobicContact CG2-CG2 3.88Å; I571-V596 HydrophobicContact CB-CG1 4.46Å; I571-V596 HydrophobicContact CD1-CG2 4.45Å; I571-V596 HydrophobicContact CG2-CG1 3.9Å; I571-V596 HydrophobicContact CG2-CG2 4.45Å
572T96.9Very high92.7Very high0 Ų045 Ų450%025%0.246CC..EExtended strand (participates in β ladder)trans-72.6147.2175.864.20000111.3F517 I518 R551 F553 V554 F570 T574 A576F517-T572 WeakPolarHBondContact O-CA 3.34Å; I518-T572 HydrophobicContact CG2-CG2 4.24Å; R551-T572 PolarHBondContact O-OG1 3.11Å; F553-T572 WeakPolarHBondContact CA-O 3.29Å; F553-T572 PolarHBondContact N-O 3.1Å; F553-T572 PolarHBondContact N-OG1 2.93Å; V554-T572 HydrophobicContact CB-CG2 4.44Å; V554-T572 PolarHBondContact N-OG1 3.21Å; V554-T572 PolarHBondContact O-N 3.31Å; F570-T572 HydrophobicContact CD2-CG2 4.32Å; F570-T572 HydrophobicContact CE2-CG2 4.13Å; T572-T574 WeakPolarHBondContact CB-O 3.31Å; T572-A576 HydrophobicContact CG2-CB 4.22Å
573V96.1Very high93.1Very high20 Ų2041.5 Ų41.512%0.12122%0.221CC..SBendtrans-112.7-6.3167.4-66.60000112.7F517 P552 V596 N600F517-V573 WeakPolarHBondContact O-CG2 3.3Å; F517-V573 PolarHBondContact O-N 2.73Å; P552-V573 WeakPolarHBondContact CB-O 3.38Å; V573-V596 HydrophobicContact CG1-CG1 3.81Å; V573-N600 HydrophobicContact CG1-CB 3.85Å; V573-N600 HydrophobicContact CG2-CB 4.48Å
574T92.9Very high93.6Very high45 Ų4537.4 Ų37.428%0.27620%0.199SC..SBendtrans-141.8158.8174.455.40000109.4S516 T572 A576S516-T574 WeakPolarHBondContact O-CG2 3.48Å; S516-T574 PolarHBondContact O-OG1 2.91Å; T572-T574 WeakPolarHBondContact CB-O 3.31Å; T574-A576 PolarHBondContact O-N 3.01Å
575P94.5Very high94Very high82 Ų8236.2 Ų36.253%0.53219%0.191SC..  trans-55.6133.9170.5-2534.5000111.8H549H549-P575 CarbonylContact O-C 3.53Å; H549-P575 WeakPolarHBondContact O-CA 3.4Å
576A92.8Very high94.2Very high0 Ų036.2 Ų36.20%019%0.191CC..  trans-136.448.2-171.300000112.3F517 H549 T572 T574 H578 L579F517-A576 HydrophobicContact CD2-CB 4.42Å; F517-A576 HydrophobicContact CE2-CB 3.81Å; H549-A576 HydrophobicContact CB-CB 4.11Å; H549-A576 WeakPolarHBondContact CB-O 3.45Å; H549-A576 PolarHBondContact O-N 3.34Å; T572-A576 HydrophobicContact CG2-CB 4.22Å; T574-A576 PolarHBondContact O-N 3.01Å; A576-H578 PolarHBondContact O-N 3.38Å; A576-L579 HydrophobicContact CB-CD1 3.78Å; A576-L579 HydrophobicContact CB-CG 4.15Å; A576-L579 WeakPolarHBondContact O-CB 3.36Å; A576-L579 WeakPolarHBondContact O-CG 3.19Å; A576-L579 PolarHBondContact O-N 3.41Å
577A90.5Very high94.4Very high64 Ų6435.8 Ų35.853%0.52919%0.187SC..G310 helixtrans-53.8-20.6-174.800000115.4H549 L579 D580H549-A577 PolarHBondContact O-N 3.2Å; A577-L579 PolarHBondContact O-N 3.07Å; A577-D580 WeakPolarHBondContact O-CB 3.45Å; A577-D580 PolarHBondContact O-N 3.08Å; A577-D580 VanDerWaalsContact O-N 3.17Å
578H90.8Very high94.4Very high112 Ų11237.5 Ų37.552%0.51920%0.196SC..G310 helixtrans-68.1-11.1175.162.1-88.5000114.3F517 A576 K582F517-H578 AromaticContact CE2-CE1 3.59Å; F517-H578 AromaticContact CE2-NE2 3.56Å; F517-H578 AromaticContact CZ-NE2 3.49Å; F517-H578 WeakPolarHBondContact CZ-NE2 3.34Å; A576-H578 PolarHBondContact O-N 3.38Å; H578-K582 PolarHBondContact O-NZ 3.45Å; H578-K582 VanDerWaalsContact O-NZ 3.1Å
579L92.8Very high94.4Very high18 Ų1836.7 Ų36.79%0.09419%0.192CC..G310 helixtrans-92.5-10.7174.9-57.5-177.3000113F517 F570 A576 A577 K582 H583F517-L579 HydrophobicContact CE2-CD1 4.05Å; F517-L579 HydrophobicContact CZ-CD1 3.94Å; F517-L579 HydrophobicContact CZ-CD2 4.41Å; F517-L579 HydrophobicContact CZ-CG 4.49Å; F570-L579 HydrophobicContact CE2-CD1 3.73Å; F570-L579 HydrophobicContact CZ-CD1 3.74Å; A576-L579 HydrophobicContact CB-CD1 3.78Å; A576-L579 HydrophobicContact CB-CG 4.15Å; A576-L579 WeakPolarHBondContact O-CB 3.36Å; A576-L579 WeakPolarHBondContact O-CG 3.19Å; A576-L579 PolarHBondContact O-N 3.41Å; A577-L579 PolarHBondContact O-N 3.07Å; L579-K582 WeakPolarHBondContact O-CB 3.26Å; L579-K582 PolarHBondContact O-N 3.2Å; L579-K582 VanDerWaalsContact O-N 3.14Å; L579-H583 PolarHBondContact O-N 3.4Å
580D89.5Confident94.2Very high44 Ų4441.5 Ų41.524%0.23522%0.215CC..THydrogen-bonded Turntrans-60.1138.9178.7-70.5-16.2000111.2H549 A577 K582H549-D580 IonicContact CE1-OD1 3.65Å; H549-D580 IonicContact CG-OD1 3.89Å; H549-D580 PolarHBondContact N-OD1 3.29Å; H549-D580 IonicContact ND1-OD1 3.48Å; H549-D580 PolarHBondContact ND1-OD1 3.26Å; A577-D580 WeakPolarHBondContact O-CB 3.45Å; A577-D580 PolarHBondContact O-N 3.08Å; A577-D580 VanDerWaalsContact O-N 3.17Å; D580-K582 PolarHBondContact O-N 3.11Å
581K86.2Confident94.1Very high173 Ų17347 Ų4775%0.75224%0.239SC*.THydrogen-bonded Turntrans59.218.1-176-52.6-179.4177.7-177.50114.7F543F543-K581 HydrophobicContact CD2-CB 4.49Å; F543-K581 WeakPolarHBondContact CE2-O 3.09Å; F543-K581 WeakPolarHBondContact CZ-O 3.39Å
582K86.1Confident93.9Very high119 Ų11947 Ų4752%0.51724%0.239SC..THydrogen-bonded Turntrans-119.2-32.5170.6-62.6178-176.11640111.9N559 H578 L579 D580N559-K582 PolarHBondContact ND2-O 3.49Å; H578-K582 PolarHBondContact O-NZ 3.45Å; H578-K582 VanDerWaalsContact O-NZ 3.1Å; L579-K582 WeakPolarHBondContact O-CB 3.26Å; L579-K582 PolarHBondContact O-N 3.2Å; L579-K582 VanDerWaalsContact O-N 3.14Å; D580-K582 PolarHBondContact O-N 3.11Å
583H94.3Very high93.9Very high33 Ų3349.8 Ų49.815%0.15325%0.253CS..SBendtrans-128.8134.8-178.4-60-72.1000110.3S556 M557 N559 F570 L579 I585S556-H583 WeakPolarHBondContact OG-CB 3.49Å; M557-H583 WeakPolarHBondContact O-CB 3.27Å; M557-H583 PolarHBondContact O-ND1 2.88Å; M557-H583 VanDerWaalsContact O-ND1 3.16Å; N559-H583 PolarHBondContact OD1-CE1 3.23Å; N559-H583 PolarHBondContact OD1-ND1 2.84Å; F570-H583 HydrophobicContact CE1-CB 4.32Å; F570-H583 HydrophobicContact CZ-CB 4.07Å; L579-H583 PolarHBondContact O-N 3.4Å; H583-I585 PolarHBondContact O-N 2.8Å
584T96.3Very high93.9Very high0 Ų054 Ų540%027%0.271CS..  trans-74.9116.5-178.9-59.30000110.9C489 T492 D541 E542 S556 M557C489-T584 HydrophobicContact CB-CG2 4.24Å; T492-T584 HydrophobicContact CG2-CG2 4.14Å; T492-T584 WeakPolarHBondContact OG1-CG2 3.23Å; D541-T584 WeakPolarHBondContact CA-OG1 3.35Å; E542-T584 HydrophobicContact CB-CG2 3.86Å; E542-T584 PolarHBondContact N-OG1 3.26Å; S556-T584 CarbonylContact C-O 3.59Å; S556-T584 VanDerWaalsContact CA-O 3.23Å; S556-T584 WeakPolarHBondContact CA-O 3.49Å; S556-T584 PolarHBondContact OG-O 3.46Å; M557-T584 PolarHBondContact N-O 3.33Å
585I98Very high94.2Very high10 Ų1052.4 Ų52.45%0.05126%0.261CS..EExtended strand (participates in β ladder)trans-81.2120.8172.3-64.2166.4000108.6Y485 C489 L547 K548 H549 V554 M555 H583Y485-I585 HydrophobicContact CD2-CG2 4.31Å; Y485-I585 HydrophobicContact CE2-CG2 4.06Å; C489-I585 PolarHBondContact SG-O 3.26Å; L547-I585 HydrophobicContact CB-CB 4.06Å; L547-I585 HydrophobicContact CB-CD1 4.18Å; L547-I585 HydrophobicContact CB-CG2 4.11Å; L547-I585 HydrophobicContact CD1-CB 4.48Å; L547-I585 HydrophobicContact CD1-CG2 4.35Å; L547-I585 WeakPolarHBondContact CD1-O 3.23Å; K548-I585 VanDerWaalsContact CA-CD1 3.46Å; H549-I585 VanDerWaalsContact CE1-CG1 3.45Å; H549-I585 WeakPolarHBondContact CE1-CG1 3.45Å; V554-I585 HydrophobicContact CG1-CB 4.2Å; V554-I585 HydrophobicContact CG1-CD1 4Å; V554-I585 HydrophobicContact CG1-CG1 3.75Å; V554-I585 HydrophobicContact CG1-CG2 3.47Å; V554-I585 VanDerWaalsContact CG1-CG2 3.47Å; M555-I585 WeakPolarHBondContact O-CA 3.4Å; H583-I585 PolarHBondContact O-N 2.8Å
586F97.8Very high94.3Very high0 Ų048.5 Ų48.50%024%0.236CC..EExtended strand (participates in β ladder)trans-125.5-1.6-17770.6-84.6000114L484 Y485 C489 T492 V493 F496 M555 M557 F569L484-F586 WeakPolarHBondContact CA-O 3.18Å; L484-F586 HydrophobicContact CD2-CD2 4.19Å; L484-F586 HydrophobicContact CD2-CE2 4.32Å; Y485-F586 PolarHBondContact N-O 3.06Å; C489-F586 HydrophobicContact CB-CB 4.33Å; T492-F586 HydrophobicContact CG2-CB 3.51Å; T492-F586 HydrophobicContact CG2-CD1 3.73Å; T492-F586 HydrophobicContact CG2-CD2 4.33Å; T492-F586 HydrophobicContact CG2-CG 3.6Å; V493-F586 HydrophobicContact CG2-CB 4.3Å; F496-F586 HydrophobicContact CB-CD2 4.48Å; F496-F586 HydrophobicContact CB-CE2 4.01Å; F496-F586 HydrophobicContact CD1-CE2 4.05Å; F496-F586 AromaticContact CD2-CE2 3.81Å; F496-F586 HydrophobicContact CD2-CE2 3.81Å; F496-F586 HydrophobicContact CD2-CZ 4.01Å; F496-F586 HydrophobicContact CE2-CE2 4.28Å; F496-F586 HydrophobicContact CE2-CZ 4.43Å; F496-F586 HydrophobicContact CG-CD2 4.49Å; F496-F586 AromaticContact CG-CE2 3.67Å; F496-F586 HydrophobicContact CG-CE2 3.67Å; F496-F586 HydrophobicContact CG-CZ 4.31Å; M555-F586 HydrophobicContact CB-CE1 4.19Å; M555-F586 HydrophobicContact CB-CZ 4.2Å; M555-F586 HydrophobicContact CE-CE2 3.72Å; M555-F586 HydrophobicContact CE-CZ 3.73Å; M555-F586 PolarHBondContact O-N 3.49Å; M555-F586 VanDerWaalsContact O-N 3.07Å; M557-F586 HydrophobicContact CG-CD1 4.05Å; M557-F586 HydrophobicContact CG-CE1 4.2Å; M557-F586 HydrophobicContact SD-CD1 4.02Å; M557-F586 HydrophobicContact SD-CE1 3.68Å; M557-F586 HydrophobicContact SD-CZ 4.32Å; F569-F586 HydrophobicContact CB-CE1 3.87Å; F569-F586 HydrophobicContact CB-CZ 3.99Å; F569-F586 HydrophobicContact CD2-CZ 4.19Å; F569-F586 HydrophobicContact CG-CE1 4.4Å; F569-F586 HydrophobicContact CG-CZ 4.03Å
587G97.4Very high94.5Very high0 Ų053.2 Ų53.20%026%0.258CS..EExtended strand (participates in β ladder)trans-167.4177.5176.900000114.9K483 M555K483-G587 CarbonylContact O-C 3.55Å; K483-G587 WeakPolarHBondContact O-CA 3.27Å; M555-G587 PolarHBondContact N-O 2.73Å
588L97.7Very high94.8Very high36 Ų3654.4 Ų54.419%0.18826%0.255CS..EExtended strand (participates in β ladder)trans-147.3132.1179.5-178.778.4000109.8C482 K483 Y485 R551 F553 V554 H590C482-L588 CarbonylContact C-O 3.59Å; C482-L588 WeakPolarHBondContact CA-O 3.38Å; K483-L588 PolarHBondContact N-O 3.49Å; K483-L588 PolarHBondContact O-N 3.32Å; Y485-L588 VanDerWaalsContact OH-CB 3.23Å; Y485-L588 WeakPolarHBondContact OH-CB 3.39Å; R551-L588 HydrophobicContact CG-CD1 4.34Å; F553-L588 WeakPolarHBondContact O-CD1 3.25Å; V554-L588 HydrophobicContact CG2-CD1 3.97Å; L588-H590 PolarHBondContact O-N 3.36Å
589V97.6Very high95.1Very high3 Ų349 Ų492%0.01823%0.23CC..EExtended strand (participates in β ladder)trans-72.3130171.9-174.70000109.3I480 H481 F553 I571 K591 M593 V596I480-V589 HydrophobicContact CG2-CB 4.19Å; I480-V589 HydrophobicContact CG2-CG1 3.5Å; I480-V589 HydrophobicContact CG2-CG2 3.61Å; H481-V589 WeakPolarHBondContact O-CA 3.35Å; H481-V589 WeakPolarHBondContact O-CG1 3.42Å; F553-V589 HydrophobicContact CB-CB 3.87Å; F553-V589 HydrophobicContact CB-CG2 4.22Å; F553-V589 PolarHBondContact O-N 2.77Å; I571-V589 HydrophobicContact CD1-CG2 4.1Å; I571-V589 HydrophobicContact CG2-CG2 3.88Å; V589-K591 VanDerWaalsContact CG1-O 3.28Å; V589-K591 WeakPolarHBondContact CG1-O 3.04Å; V589-M593 HydrophobicContact CG1-CG 4.42Å; V589-V596 HydrophobicContact CG1-CG2 4.42Å; V589-V596 HydrophobicContact CG2-CG2 4.25Å
590H94.4Very high95.3Very high103 Ų10348.4 Ų48.448%0.47723%0.227SC..EExtended strand (participates in β ladder)trans-121-8.9178.974.483.4000113.8H481 L588 M593H481-H590 PolarHBondContact O-CD2 3.25Å; H481-H590 PolarHBondContact O-N 3.02Å; L588-H590 PolarHBondContact O-N 3.36Å; H590-M593 VanDerWaalsContact O-CE 3.25Å; H590-M593 WeakPolarHBondContact O-CE 3.32Å
591K95.6Very high95.6Very high124 Ų12451.8 Ų51.854%0.53924%0.241SC..EExtended strand (participates in β ladder)trans-151.3148.2168.7-178.8-175.6178.4-167.80108.9H481 V589H481-K591 HydrophobicContact CB-CB 3.9Å; H481-K591 PolarHBondContact N-O 3.38Å; H481-K591 PolarHBondContact O-N 2.76Å; V589-K591 VanDerWaalsContact CG1-O 3.28Å; V589-K591 WeakPolarHBondContact CG1-O 3.04Å
592G94.9Very high96Very high1 Ų145 Ų451%0.0121%0.214CC..  trans85.424.2-173.300000113.5D479 E594 V595 V596D479-G592 WeakPolarHBondContact O-CA 3.4Å; G592-E594 PolarHBondContact O-N 2.67Å; G592-V595 WeakPolarHBondContact O-CB 3.42Å; G592-V595 PolarHBondContact O-N 2.9Å; G592-V595 VanDerWaalsContact O-N 3.08Å; G592-V596 PolarHBondContact O-N 3.44Å
593M96.7Very high96.3Very high59 Ų5947.3 Ų47.329%0.29122%0.224SC..Hα-helixtrans-61.6-34.2176.2-64.982.2154.800111.8F553 V589 H590 V595 V596 Q597F553-M593 HydrophobicContact CD1-CB 4.31Å; F553-M593 HydrophobicContact CD1-CG 4.23Å; F553-M593 HydrophobicContact CD2-CB 4.43Å; F553-M593 HydrophobicContact CD2-CG 3.78Å; F553-M593 HydrophobicContact CE1-CB 3.84Å; F553-M593 HydrophobicContact CE1-CG 4.18Å; F553-M593 HydrophobicContact CE2-CB 3.98Å; F553-M593 HydrophobicContact CE2-CG 3.72Å; F553-M593 HydrophobicContact CG-CG 4.04Å; F553-M593 HydrophobicContact CZ-CB 3.66Å; F553-M593 HydrophobicContact CZ-CG 3.92Å; V589-M593 HydrophobicContact CG1-CG 4.42Å; H590-M593 VanDerWaalsContact O-CE 3.25Å; H590-M593 WeakPolarHBondContact O-CE 3.32Å; M593-V595 VanDerWaalsContact C-N 3.29Å; M593-V595 PolarHBondContact O-N 2.77Å; M593-V596 WeakPolarHBondContact O-CB 3.23Å; M593-V596 PolarHBondContact O-N 2.76Å; M593-Q597 WeakPolarHBondContact O-CG 3.39Å; M593-Q597 PolarHBondContact O-N 2.58Å
594E96.1Very high96.4Very high107 Ų10746.8 Ų46.850%0.522%0.224SC..Hα-helixtrans-60.2-3717364.6-77.9-173.700111.9G592 Q597 N598G592-E594 PolarHBondContact O-N 2.67Å; E594-Q597 PolarHBondContact O-N 2.75Å; E594-N598 VanDerWaalsContact O-CB 3.32Å; E594-N598 WeakPolarHBondContact O-CB 3.47Å; E594-N598 PolarHBondContact O-N 3.13Å; E594-N598 PolarHBondContact O-ND2 3.47Å; E594-N598 PolarHBondContact O-OD1 2.87Å
595V97.6Very high96.1Very high12 Ų1249.2 Ų49.27%0.07324%0.237CC..Hα-helixtrans-66.9-46.9175.2-179.50000109.8M477 I480 G592 M593 Q597 N598 I599M477-V595 HydrophobicContact CB-CG1 4.25Å; I480-V595 HydrophobicContact CD1-CG1 4.25Å; I480-V595 HydrophobicContact CG1-CB 4.09Å; I480-V595 HydrophobicContact CG1-CG1 3.89Å; G592-V595 WeakPolarHBondContact O-CB 3.42Å; G592-V595 PolarHBondContact O-N 2.9Å; G592-V595 VanDerWaalsContact O-N 3.08Å; M593-V595 VanDerWaalsContact C-N 3.29Å; M593-V595 PolarHBondContact O-N 2.77Å; V595-Q597 VanDerWaalsContact C-N 3.29Å; V595-Q597 PolarHBondContact O-N 3.06Å; V595-N598 PolarHBondContact O-N 3.12Å; V595-I599 HydrophobicContact CG1-CD1 4.02Å; V595-I599 HydrophobicContact CG1-CG1 4.47Å; V595-I599 VanDerWaalsContact O-CG1 3.29Å; V595-I599 WeakPolarHBondContact O-CG1 3.29Å; V595-I599 PolarHBondContact O-N 2.97Å
596V97.4Very high95.6Very high0 Ų054.1 Ų54.10%027%0.269CS..Hα-helixtrans-57.6-43.3175.6178.60000111.1I480 I519 F553 I571 V573 V589 G592 M593 N600I480-V596 HydrophobicContact CD1-CG2 3.83Å; I480-V596 HydrophobicContact CG1-CG2 4.03Å; I480-V596 HydrophobicContact CG2-CG2 3.85Å; I519-V596 HydrophobicContact CD1-CB 4.35Å; I519-V596 HydrophobicContact CD1-CG1 3.74Å; I519-V596 HydrophobicContact CG1-CG1 4.29Å; F553-V596 HydrophobicContact CD1-CB 4.26Å; F553-V596 HydrophobicContact CD1-CG1 3.99Å; F553-V596 HydrophobicContact CE1-CB 4.37Å; F553-V596 HydrophobicContact CE1-CG1 4.28Å; I571-V596 HydrophobicContact CB-CG1 4.46Å; I571-V596 HydrophobicContact CD1-CG2 4.45Å; I571-V596 HydrophobicContact CG2-CG1 3.9Å; I571-V596 HydrophobicContact CG2-CG2 4.45Å; V573-V596 HydrophobicContact CG1-CG1 3.81Å; V589-V596 HydrophobicContact CG1-CG2 4.42Å; V589-V596 HydrophobicContact CG2-CG2 4.25Å; G592-V596 PolarHBondContact O-N 3.44Å; M593-V596 WeakPolarHBondContact O-CB 3.23Å; M593-V596 PolarHBondContact O-N 2.76Å; V596-N600 WeakPolarHBondContact O-CB 3.24Å; V596-N600 PolarHBondContact O-N 2.78Å
597Q96.2Very high95Very high100 Ų10063.3 Ų63.347%0.46731%0.309SS..Hα-helixtrans-66.2-43.5176.8-74-178.3-8.100112F553 M593 E594 V595 I599 N600 Q601F553-Q597 HydrophobicContact CE1-CG 4.13Å; F553-Q597 HydrophobicContact CZ-CG 4.33Å; M593-Q597 WeakPolarHBondContact O-CG 3.39Å; M593-Q597 PolarHBondContact O-N 2.58Å; E594-Q597 PolarHBondContact O-N 2.75Å; V595-Q597 VanDerWaalsContact C-N 3.29Å; V595-Q597 PolarHBondContact O-N 3.06Å; Q597-I599 VanDerWaalsContact C-N 3.35Å; Q597-I599 PolarHBondContact O-N 3.27Å; Q597-N600 PolarHBondContact O-N 3.31Å; Q597-Q601 VanDerWaalsContact O-CG 3.32Å; Q597-Q601 WeakPolarHBondContact O-CG 3.34Å; Q597-Q601 PolarHBondContact O-N 2.91Å
598N96.6Very high94.6Very high88 Ų8867.2 Ų67.247%0.47133%0.33SS..Hα-helixtrans-60.3-45.6177.5-71.8-18.6000111.1M477 E594 V595 N600 Q601 V602M477-N598 HydrophobicContact CE-CB 4.48Å; E594-N598 VanDerWaalsContact O-CB 3.32Å; E594-N598 WeakPolarHBondContact O-CB 3.47Å; E594-N598 PolarHBondContact O-N 3.13Å; E594-N598 PolarHBondContact O-ND2 3.47Å; E594-N598 PolarHBondContact O-OD1 2.87Å; V595-N598 PolarHBondContact O-N 3.12Å; N598-N600 VanDerWaalsContact C-N 3.28Å; N598-N600 PolarHBondContact O-N 3.04Å; N598-Q601 PolarHBondContact O-N 2.89Å; N598-V602 VanDerWaalsContact O-CG1 3.29Å; N598-V602 WeakPolarHBondContact O-CG1 3.24Å; N598-V602 PolarHBondContact O-N 3.23Å
599I97.2Very high94.4Very high0 Ų067.9 Ų67.90%033%0.334CS..Hα-helixtrans-59.2-41.1173.6-63.5171.9000110.2T475 M477 I480 F510 V513 I519 V595 Q597 Q601 V602 I615T475-I599 HydrophobicContact CG2-CD1 4.49Å; M477-I599 HydrophobicContact CB-CG1 4.17Å; M477-I599 HydrophobicContact CG-CG1 4.32Å; M477-I599 HydrophobicContact SD-CG1 3.77Å; I480-I599 HydrophobicContact CD1-CD1 4.26Å; F510-I599 HydrophobicContact CB-CG2 4.46Å; F510-I599 HydrophobicContact CD1-CG2 4.34Å; F510-I599 HydrophobicContact CE2-CD1 4.15Å; F510-I599 HydrophobicContact CG-CG2 4.23Å; F510-I599 HydrophobicContact CZ-CD1 4.18Å; V513-I599 HydrophobicContact CG2-CG2 4.27Å; I519-I599 HydrophobicContact CB-CG2 4.25Å; I519-I599 HydrophobicContact CD1-CB 4.23Å; I519-I599 HydrophobicContact CD1-CD1 4.35Å; I519-I599 HydrophobicContact CD1-CG2 4.03Å; I519-I599 HydrophobicContact CG2-CB 4.45Å; I519-I599 HydrophobicContact CG2-CG2 3.88Å; V595-I599 HydrophobicContact CG1-CD1 4.02Å; V595-I599 HydrophobicContact CG1-CG1 4.47Å; V595-I599 VanDerWaalsContact O-CG1 3.29Å; V595-I599 WeakPolarHBondContact O-CG1 3.29Å; V595-I599 PolarHBondContact O-N 2.97Å; Q597-I599 VanDerWaalsContact C-N 3.35Å; Q597-I599 PolarHBondContact O-N 3.27Å; I599-Q601 VanDerWaalsContact C-N 3.32Å; I599-Q601 PolarHBondContact O-N 3.44Å; I599-V602 WeakPolarHBondContact O-CG2 3.39Å; I599-I615 HydrophobicContact CB-CD1 4.48Å; I599-I615 HydrophobicContact CD1-CG2 4.15Å; I599-I615 HydrophobicContact CG1-CD1 4.42Å; I599-I615 HydrophobicContact CG1-CG2 4.12Å; I599-I615 HydrophobicContact CG2-CD1 4Å
600N97.2Very high94.2Very high4 Ų471.7 Ų71.72%0.02135%0.348CS..Hα-helixtrans-68.7-26.9179.2-168.4-105.3000114.2I514 S516 I518 I519 V573 V596 Q597 N598I514-N600 PolarHBondContact O-ND2 3.21Å; S516-N600 PolarHBondContact N-OD1 2.88Å; I518-N600 PolarHBondContact O-ND2 3.44Å; I519-N600 HydrophobicContact CG2-CB 3.87Å; V573-N600 HydrophobicContact CG1-CB 3.85Å; V573-N600 HydrophobicContact CG2-CB 4.48Å; V596-N600 WeakPolarHBondContact O-CB 3.24Å; V596-N600 PolarHBondContact O-N 2.78Å; Q597-N600 PolarHBondContact O-N 3.31Å; N598-N600 VanDerWaalsContact C-N 3.28Å; N598-N600 PolarHBondContact O-N 3.04Å
601Q95.4Very high94.2Very high116 Ų11667.3 Ų67.354%0.54233%0.328SS..Hα-helixtrans-86.7-8.5-177.2-69.3-59.9-22.400114.2Q597 N598 I599Q597-Q601 VanDerWaalsContact O-CG 3.32Å; Q597-Q601 WeakPolarHBondContact O-CG 3.34Å; Q597-Q601 PolarHBondContact O-N 2.91Å; N598-Q601 PolarHBondContact O-N 2.89Å; I599-Q601 VanDerWaalsContact C-N 3.32Å; I599-Q601 PolarHBondContact O-N 3.44Å
602V94.8Very high94Very high29 Ų2968.4 Ų68.418%0.17633%0.333CS..SBendtrans-59.3155.9179.5-54.80000112.2M477 N598 I599 T604 P611 I615M477-V602 HydrophobicContact CE-CG1 4.4Å; M477-V602 HydrophobicContact SD-CG1 4.17Å; N598-V602 VanDerWaalsContact O-CG1 3.29Å; N598-V602 WeakPolarHBondContact O-CG1 3.24Å; N598-V602 PolarHBondContact O-N 3.23Å; I599-V602 WeakPolarHBondContact O-CG2 3.39Å; V602-T604 HydrophobicContact CG2-CG2 4.22Å; V602-T604 PolarHBondContact O-N 3.3Å; V602-P611 HydrophobicContact CG2-CB 3.91Å; V602-P611 HydrophobicContact CG2-CG 3.99Å; V602-I615 HydrophobicContact CB-CD1 4.34Å; V602-I615 HydrophobicContact CG1-CD1 3.73Å; V602-I615 HydrophobicContact CG2-CD1 3.96Å
603K94.1Very high93.8Very high169 Ų16976.3 Ų76.374%0.73537%0.37SS*.  trans-70.6123.5176-67.6178.6-178.1172.80108.8F612K603-F612 HydrophobicContact CB-CD2 3.99Å; K603-F612 WeakPolarHBondContact O-CD2 3.4Å; K603-F612 PolarHBondContact O-N 3.06Å
604T94.6Very high93.5Very high22 Ų2279.9 Ų79.914%0.13539%0.386CS..BIsolated β-bridgetrans-114.8152.9177.758.90000110.8V513 V602 P606 R610 P611 F612V513-T604 HydrophobicContact CB-CG2 3.84Å; V513-T604 HydrophobicContact CG1-CG2 4.01Å; V602-T604 HydrophobicContact CG2-CG2 4.22Å; V602-T604 PolarHBondContact O-N 3.3Å; T604-P606 WeakPolarHBondContact O-CD 3.4Å; T604-R610 CarbonylContact C-O 3.55Å; T604-R610 VanDerWaalsContact CA-O 3.24Å; T604-R610 WeakPolarHBondContact CA-O 3.47Å; T604-P611 HydrophobicContact CG2-CG 4.28Å; T604-F612 WeakPolarHBondContact O-CE2 3.48Å
605N90.6Very high93.5Very high51 Ų5175.2 Ų75.227%0.27336%0.364SS..  trans-68.5120.9172.1178.1-20000109.1K607 N608 N609 R610 F612N605-K607 PolarHBondContact O-N 2.96Å; N605-K607 WeakPolarHBondContact OD1-CB 3.43Å; N605-K607 PolarHBondContact OD1-N 3.41Å; N605-N608 WeakPolarHBondContact CB-OD1 3.38Å; N605-N608 PolarHBondContact O-N 3.18Å; N605-N609 VanDerWaalsContact O-CA 3.31Å; N605-N609 WeakPolarHBondContact O-CA 3.42Å; N605-N609 PolarHBondContact O-N 3.29Å; N605-R610 PolarHBondContact N-O 3.17Å; N605-F612 HydrophobicContact CB-CZ 4.22Å
606P86.9Confident93.3Very high113 Ų11375.6 Ų75.673%0.73437%0.368SS*.THydrogen-bonded Turntrans-58.8-22.3-177.4-26.134.9000115T604T604-P606 WeakPolarHBondContact O-CD 3.4Å
607K86.7Confident93.3Very high193 Ų19375.6 Ų75.684%0.83937%0.368SS*.THydrogen-bonded Turntrans-76.2-36.8-177.5-68.5-173.3177.7-177.90113.5N605N605-K607 PolarHBondContact O-N 2.96Å; N605-K607 WeakPolarHBondContact OD1-CB 3.43Å; N605-K607 PolarHBondContact OD1-N 3.41Å
608N88Confident93Very high82 Ų8274.8 Ų74.844%0.43937%0.369SS..THydrogen-bonded Turntrans-131.40.3-172.364.31.5000113.7N605 R610N605-N608 WeakPolarHBondContact CB-OD1 3.38Å; N605-N608 PolarHBondContact O-N 3.18Å; N608-R610 PolarHBondContact O-N 2.87Å; N608-R610 VanDerWaalsContact OD1-CB 3.28Å; N608-R610 WeakPolarHBondContact OD1-CB 3.23Å; N608-R610 PolarHBondContact OD1-N 2.97Å
609N93.7Very high92.8Very high50 Ų5072.5 Ų72.527%0.26736%0.36SS..  trans60.122-176.6-55.7-73.4000113.8R512 V513 I514 N605R512-N609 HydrophobicContact CG-CB 4.21Å; V513-N609 PolarHBondContact N-O 3.46Å; V513-N609 WeakPolarHBondContact O-CB 3.37Å; I514-N609 HydrophobicContact CG1-CB 4.03Å; N605-N609 VanDerWaalsContact O-CA 3.31Å; N605-N609 WeakPolarHBondContact O-CA 3.42Å; N605-N609 PolarHBondContact O-N 3.29Å
610R93.4Very high92.6Very high83 Ų8373.2 Ų73.231%0.31336%0.364SS..  trans-80.6132.8175.5-170.1-175.6-174.491.3-4.3110.4H511 G526 T604 N605 N608H511-R610 WeakPolarHBondContact O-CA 3.21Å; G526-R610 PolarHBondContact O-NH1 3.07Å; T604-R610 CarbonylContact C-O 3.55Å; T604-R610 VanDerWaalsContact CA-O 3.24Å; T604-R610 WeakPolarHBondContact CA-O 3.47Å; N605-R610 PolarHBondContact N-O 3.17Å; N608-R610 PolarHBondContact O-N 2.87Å; N608-R610 VanDerWaalsContact OD1-CB 3.28Å; N608-R610 WeakPolarHBondContact OD1-CB 3.23Å; N608-R610 PolarHBondContact OD1-N 2.97Å
611P93.8Very high92.3Very high11 Ų1175.1 Ų75.17%0.07138%0.377CS..BIsolated β-bridgetrans-53.2142.5169.6-28.337.5000112.8F510 V513 V602 T604 E613F510-P611 VanDerWaalsContact O-CD 3.25Å; F510-P611 WeakPolarHBondContact O-CD 3.04Å; F510-P611 WeakPolarHBondContact O-CG 3.46Å; V513-P611 HydrophobicContact CB-CG 4.16Å; V513-P611 HydrophobicContact CG2-CG 3.72Å; V602-P611 HydrophobicContact CG2-CB 3.91Å; V602-P611 HydrophobicContact CG2-CG 3.99Å; T604-P611 HydrophobicContact CG2-CG 4.28Å; P611-E613 WeakPolarHBondContact CB-O 3.28Å
612F91.8Very high92Very high146 Ų14672.2 Ų72.264%0.6436%0.363SS*.SBendtrans-72.5-40.9172.5-80-75.8000112.1K603 T604 N605K603-F612 HydrophobicContact CB-CD2 3.99Å; K603-F612 WeakPolarHBondContact O-CD2 3.4Å; K603-F612 PolarHBondContact O-N 3.06Å; T604-F612 WeakPolarHBondContact O-CE2 3.48Å; N605-F612 HydrophobicContact CB-CZ 4.22Å
613E91Very high91.2Very high167 Ų16774 Ų7478%0.7838%0.375SS*.SBendtrans-94.3131.1172.3-69.3174.8-167.300108.3P611 I615P611-E613 WeakPolarHBondContact CB-O 3.28Å; E613-I615 PolarHBondContact O-N 3.18Å
614E90.3Very high89.3Confident135 Ų13570.7 Ų70.763%0.63137%0.374SS*.  trans-72.3129.2-175.8-171.9171.5122.600111V509V509-E614 HydrophobicContact CB-CG 4.29Å; V509-E614 HydrophobicContact CG1-CG 3.41Å; V509-E614 VanDerWaalsContact CG1-CG 3.41Å; V509-E614 VanDerWaalsContact CG1-OE1 3.31Å; V509-E614 WeakPolarHBondContact CG1-OE1 3.32Å
615I95.4Very high87Confident9 Ų975.6 Ų75.65%0.04640%0.403CS..  trans-119.8121.8174.3-55.3161.2000106.3T476 M477 V509 F510 I599 V602 E613T476-I615 WeakPolarHBondContact OG1-CG2 2.93Å; M477-I615 HydrophobicContact CG-CG1 4.32Å; M477-I615 HydrophobicContact CG-CG2 3.99Å; M477-I615 HydrophobicContact SD-CD1 3.65Å; M477-I615 HydrophobicContact SD-CG1 3.99Å; M477-I615 HydrophobicContact SD-CG2 4.36Å; V509-I615 CarbonylContact C-O 3.6Å; V509-I615 WeakPolarHBondContact CA-O 3.39Å; F510-I615 HydrophobicContact CD2-CB 4.21Å; F510-I615 HydrophobicContact CD2-CG2 3.72Å; F510-I615 WeakPolarHBondContact CD2-O 3.43Å; F510-I615 HydrophobicContact CE2-CG2 4.19Å; F510-I615 PolarHBondContact N-O 3.14Å; I599-I615 HydrophobicContact CB-CD1 4.48Å; I599-I615 HydrophobicContact CD1-CG2 4.15Å; I599-I615 HydrophobicContact CG1-CD1 4.42Å; I599-I615 HydrophobicContact CG1-CG2 4.12Å; I599-I615 HydrophobicContact CG2-CD1 4Å; V602-I615 HydrophobicContact CB-CD1 4.34Å; V602-I615 HydrophobicContact CG1-CD1 3.73Å; V602-I615 HydrophobicContact CG2-CD1 3.96Å; E613-I615 PolarHBondContact O-N 3.18Å
616S94.7Very high84.3Confident20 Ų2079.7 Ų79.714%0.1443%0.425CS..BIsolated β-bridgetrans-125.3158.9-179.4590000112.8T475 T476 N508T475-S616 WeakPolarHBondContact CA-O 3.49Å; T476-S616 WeakPolarHBondContact CG2-OG 3.15Å; T476-S616 PolarHBondContact N-O 2.8Å; T476-S616 PolarHBondContact OG1-N 2.67Å; T476-S616 VanDerWaalsContact OG1-N 3.1Å; T476-S616 PolarHBondContact OG1-O 3Å; N508-S616 CarbonylContact O-C 3.53Å; N508-S616 VanDerWaalsContact O-CA 3.29Å; N508-S616 WeakPolarHBondContact O-CA 3.42Å
617I97.4Very high81.7Confident0 Ų083.3 Ų83.30%043%0.432CS..EExtended strand (participates in β ladder)trans-76.1125.4165.3-62.5173.2000107.5I473 H474 Y505 G507 N508 F510 T521 I620I473-I617 HydrophobicContact CG2-CD1 4.11Å; I473-I617 HydrophobicContact CG2-CG1 3.93Å; I473-I617 HydrophobicContact CG2-CG2 4.09Å; H474-I617 CarbonylContact O-C 3.4Å; Y505-I617 WeakPolarHBondContact O-CB 3.16Å; G507-I617 WeakPolarHBondContact CA-O 3.39Å; G507-I617 PolarHBondContact N-O 2.81Å; N508-I617 PolarHBondContact O-N 2.93Å; F510-I617 HydrophobicContact CE2-CG1 4.04Å; F510-I617 HydrophobicContact CZ-CG1 4.27Å; T521-I617 HydrophobicContact CG2-CD1 3.94Å; I617-I620 HydrophobicContact CG2-CD1 4.48Å; I617-I620 HydrophobicContact CG2-CG1 3.95Å
618V90.4Very high79.2Confident83 Ų8381.3 Ų81.350%0.50343%0.43SS..EExtended strand (participates in β ladder)trans-79.7-50.6173.3179.20000109.4H474 T476H474-V618 HydrophobicContact CB-CB 4.37Å; H474-V618 PolarHBondContact O-N 3.31Å; T476-V618 HydrophobicContact CG2-CG2 4.18Å
619S90.7Very high76.6Confident40 Ų4080.8 Ų80.828%0.2844%0.444SS..EExtended strand (participates in β ladder)trans-162.9169.4176.862.40000111.3H474 N506H474-S619 WeakPolarHBondContact CB-O 3.47Å; H474-S619 PolarHBondContact CD2-OG 3.2Å; H474-S619 PolarHBondContact N-O 2.78Å; H474-S619 PolarHBondContact O-N 2.8Å; N506-S619 WeakPolarHBondContact OD1-CA 3.15Å
620I94.3Very high73.5Confident14 Ų1486 Ų867%0.07247%0.467CS..EExtended strand (participates in β ladder)trans-124.6123.8171.1-58179.6000108.1C471 V472 I473 F496 A500 Y505 I617 F622C471-I620 HydrophobicContact CB-CG2 4.07Å; V472-I620 CarbonylContact O-C 3.58Å; V472-I620 VanDerWaalsContact O-CA 3.32Å; V472-I620 WeakPolarHBondContact O-CA 3.35Å; I473-I620 HydrophobicContact CB-CG1 4.47Å; I473-I620 HydrophobicContact CG1-CD1 4.29Å; I473-I620 HydrophobicContact CG1-CG1 4.26Å; I473-I620 HydrophobicContact CG2-CG1 4.22Å; F496-I620 HydrophobicContact CE2-CD1 4.14Å; F496-I620 HydrophobicContact CZ-CD1 3.87Å; F496-I620 HydrophobicContact CZ-CG2 4.49Å; A500-I620 HydrophobicContact CB-CB 3.9Å; A500-I620 HydrophobicContact CB-CD1 4.07Å; A500-I620 HydrophobicContact CB-CG2 3.96Å; Y505-I620 HydrophobicContact CD2-CD1 3.68Å; Y505-I620 HydrophobicContact CG-CD1 3.94Å; I617-I620 HydrophobicContact CG2-CD1 4.48Å; I617-I620 HydrophobicContact CG2-CG1 3.95Å; I620-F622 HydrophobicContact CG2-CE1 4.43Å; I620-F622 HydrophobicContact CG2-CZ 4.13Å
621S90.6Very high70.8Confident44 Ų4488.2 Ų88.231%0.30849%0.492SS..EExtended strand (participates in β ladder)trans-111.8158.417968.20000111.6C471 V472 H474C471-S621 CarbonylContact C-O 3.54Å; C471-S621 WeakPolarHBondContact CA-O 3.43Å; C471-S621 WeakPolarHBondContact CB-O 3.26Å; V472-S621 PolarHBondContact N-O 3.29Å; V472-S621 PolarHBondContact O-N 2.87Å; H474-S621 PolarHBondContact NE2-OG 3.22Å
622F89Confident68.1Low55 Ų5596 Ų9624%0.24153%0.527CS..  trans-121108.2-179.2-60.4-73.8000108.2I468 C471 T497 A500 K501 I620 S624I468-F622 HydrophobicContact CD1-CD1 4.35Å; I468-F622 HydrophobicContact CD1-CG 4.46Å; I468-F622 HydrophobicContact CG2-CD1 3.29Å; I468-F622 HydrophobicContact CG2-CE1 3.73Å; I468-F622 HydrophobicContact CG2-CG 4.13Å; C471-F622 HydrophobicContact CB-CD1 3.63Å; C471-F622 HydrophobicContact CB-CE1 3.53Å; T497-F622 HydrophobicContact CG2-CE1 3.73Å; T497-F622 HydrophobicContact CG2-CZ 4.06Å; A500-F622 HydrophobicContact CB-CE2 4.05Å; A500-F622 HydrophobicContact CB-CZ 3.68Å; K501-F622 HydrophobicContact CG-CD2 4.12Å; K501-F622 HydrophobicContact CG-CE2 3.64Å; I620-F622 HydrophobicContact CG2-CE1 4.43Å; I620-F622 HydrophobicContact CG2-CZ 4.13Å; F622-S624 PolarHBondContact O-N 2.74Å
623P77.4Confident65.5Low66 Ų6697.8 Ų97.843%0.42956%0.558SS.*  trans-63.7130.6178.34.60.7000109.9V472 T625V472-P623 HydrophobicContact CG2-CG 4.11Å; P623-T625 PolarHBondContact O-N 2.85Å
624S55.5Low64.2Low101 Ų10194.4 Ų94.471%0.70655%0.547SS*.  trans-72.5117.6175.346.90000110.1F622 L626F622-S624 PolarHBondContact O-N 2.74Å; S624-L626 PolarHBondContact O-N 2.7Å
625T44.5Very low62.8Low124 Ų12492.2 Ų92.276%0.76154%0.543SS*.  trans-75.363.9169.3-130000110.1P623P623-T625 PolarHBondContact O-N 2.85Å
626L34.4Very low61Low137 Ų13796.8 Ų96.872%0.71757%0.57SS**  trans-101.6100.1160-74.1166.5000105.2S624 D628S624-L626 PolarHBondContact O-N 2.7Å; L626-D628 VanDerWaalsContact C-N 3.29Å; L626-D628 PolarHBondContact O-N 2.64Å
627Q31.9Very low59.1Low189 Ų189101.4 Ų101.488%0.88360%0.595SS**  trans-64.3101.1162-80.7178.2-5.600105.9G629Q627-G629 PolarHBondContact O-N 3.48Å
628D34.1Very low56.7Low151 Ų151107.7 Ų107.781%0.80763%0.633SS**  trans-55.6104.1164.3-71-40.4000106.8L626 E630L626-D628 VanDerWaalsContact C-N 3.29Å; L626-D628 PolarHBondContact O-N 2.64Å; D628-E630 PolarHBondContact O-N 2.75Å; D628-E630 VanDerWaalsContact O-N 3.15Å
629G33.6Very low54.4Low71 Ų71109.3 Ų109.373%0.73264%0.641SS**  trans-57.4118.8174.900000108.6Q627Q627-G629 PolarHBondContact O-N 3.48Å
630E28Very low51.8Low160 Ų160114.3 Ų114.375%0.74867%0.667SS**  trans-51.8133.7170.7-72.3-176150.100109.3D628 H632D628-E630 PolarHBondContact O-N 2.75Å; D628-E630 VanDerWaalsContact O-N 3.15Å; E630-H632 PolarHBondContact O-N 2.95Å
631P37.6Very low48.5Very low130 Ų130122 Ų12284%0.84471%0.713SS**  trans-71.4101.3174.829.6-30.4000107.2S633P631-S633 PolarHBondContact O-N 3.22Å; P631-S633 VanDerWaalsContact O-N 3.07Å
632H36.8Very low45Very low174 Ų174128.5 Ų128.581%0.80675%0.747SS**  trans-60.3115166.9-74.9-61000108.5E630E630-H632 PolarHBondContact O-N 2.95Å
633S37.5Very low41Very low184 Ų184135.2 Ų135.2100%1.28779%0.793SS**  trans-38.1017053.60000115.4P631P631-S633 PolarHBondContact O-N 3.22Å; P631-S633 VanDerWaalsContact O-N 3.07Å

Retrieved 633 of 633 residues in 443.3 ms (Link to these results)