A0A077Z697_TRITR Loading...

ATP-dependent 6-phosphofructokinase

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.

AlphaFold DB , UniProt , Accession A0A077Z697, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 791 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M29.1Very low31.5Very low248 Ų248153.5 Ų153.5100%1.22276%0.757SS**  032.10-73.5-165.7-77.900113.4
2A27.6Very low32.2Very low109 Ų109150.2 Ų150.290%0.90176%0.76SS**  trans-115.336174.600000111.8
3A25.9Very low33.5Very low95 Ų95141.8 Ų141.879%0.78573%0.734SS**  trans-127.259-178.400000109.7
4E26.2Very low35.4Very low186 Ų186135 Ų13587%0.86972%0.716SS**SBendtrans-154.4130.1169-115.6166.3-167.600110.3
5K28.1Very low37.6Very low201 Ų201126.4 Ų126.487%0.87467%0.671SS**  trans73.667.5177.8-59.8-177.7177.6-179.50117.6E7K5-E7 PolarHBondContact O-N 3.28Å
6R29.2Very low40.4Very low202 Ų202121.6 Ų121.676%0.76265%0.646SS**  trans-83.695139.5-87.8-175175.5-170.2-0.4107.5R8 E22R6-R8 PolarHBondContact O-N 3.32Å; R6-E22 IonicContact NH1-OE2 2.82Å; R6-E22 PolarHBondContact NH1-OE2 3.35Å
7E27.5Very low43.1Very low182 Ų182118.5 Ų118.585%0.8563%0.629SS**  trans-56.7107.5169.1-115.7173.8-178.400108.5K5 R9K5-E7 PolarHBondContact O-N 3.28Å; E7-R9 PolarHBondContact O-N 3.34Å
8R38.1Very low45.3Very low127 Ų127112.7 Ų112.748%0.47960%0.602SS.*  trans-67.3105.2175.1-70.8-178-178.6-175.5-0.9106.9R6 T10 L16R6-R8 PolarHBondContact O-N 3.32Å; R8-T10 PolarHBondContact O-N 2.82Å; R8-L16 HydrophobicContact CB-CD2 4.05Å
9R36.6Very low47.4Very low208 Ų208110.7 Ų110.779%0.78559%0.585SS**  trans-55.5101.6177.2-79.2-179.1175.8-179.5-1.9109.7E7 L17E7-R9 PolarHBondContact O-N 3.34Å; R9-L17 HydrophobicContact CB-CD1 3.94Å
10T33.5Very low49.1Very low106 Ų106107.2 Ų107.265%0.6557%0.565SS**EExtended strand (participates in β ladder)trans-73.8128.8172.844.20000109.1R8 L16R8-T10 PolarHBondContact O-N 2.82Å; T10-L16 HydrophobicContact CG2-CD2 4.07Å
11T45Very low50.5Low24 Ų24103.9 Ų103.915%0.14756%0.557CS.*EExtended strand (participates in β ladder)trans-88.6155.1172.753.60000109.9G13 G14 S15 L17T11-G13 PolarHBondContact O-N 2.98Å; T11-G14 PolarHBondContact O-N 3.41Å; T11-S15 PolarHBondContact N-O 3.17Å; T11-S15 VanDerWaalsContact OG1-CB 3.31Å; T11-S15 WeakPolarHBondContact OG1-CB 3.47Å; T11-S15 PolarHBondContact OG1-O 3.17Å; T11-S15 PolarHBondContact OG1-OG 3.13Å; T11-L17 HydrophobicContact CG2-CD2 4.31Å; T11-L17 HydrophobicContact CG2-CG 4.15Å
12S40.1Very low53.2Low114 Ų11495.6 Ų95.680%0.79752%0.515SS*.THydrogen-bonded Turntrans-52.8110.2-178.958.80000110.8
13G49Very low55.8Low41 Ų4196.3 Ų96.342%0.42350%0.5SS..THydrogen-bonded Turntrans119.52.4-179.100000116.3T11 K366T11-G13 PolarHBondContact O-N 2.98Å; G13-K366 PolarHBondContact O-NZ 3.2Å
14G59Low58.5Low47 Ų4792.9 Ų92.949%0.48547%0.469SS..THydrogen-bonded Turntrans87.510.8176.500000114.2T11T11-G14 PolarHBondContact O-N 3.41Å
15S69Low61.4Low6 Ų692.6 Ų92.64%0.04246%0.46CS..EExtended strand (participates in β ladder)trans-82.1133.5174.332.80000111.3T11 R361T11-S15 PolarHBondContact N-O 3.17Å; T11-S15 VanDerWaalsContact OG1-CB 3.31Å; T11-S15 WeakPolarHBondContact OG1-CB 3.47Å; T11-S15 PolarHBondContact OG1-O 3.17Å; T11-S15 PolarHBondContact OG1-OG 3.13Å; S15-R361 WeakPolarHBondContact CA-O 3.44Å
16L83Confident64.2Low49 Ų4986.1 Ų86.126%0.25744%0.439SS..EExtended strand (participates in β ladder)trans-93.3138.9174.3-65169.4000109.2R8 T10 V360 R361R8-L16 HydrophobicContact CB-CD2 4.05Å; T10-L16 HydrophobicContact CG2-CD2 4.07Å; L16-V360 CarbonylContact O-C 3.54Å; L16-V360 WeakPolarHBondContact O-CA 3.33Å; L16-V360 WeakPolarHBondContact O-CB 3.28Å; L16-R361 HydrophobicContact CB-CB 4.32Å; L16-R361 PolarHBondContact N-O 2.96Å; L16-R361 PolarHBondContact O-N 3.18Å
17L85.4Confident67.1Low69 Ų6982 Ų8236%0.36143%0.431SS..EExtended strand (participates in β ladder)trans-63.2142.2170.8-74.1161.8000110.2R9 T11 T358 V360R9-L17 HydrophobicContact CB-CD1 3.94Å; T11-L17 HydrophobicContact CG2-CD2 4.31Å; T11-L17 HydrophobicContact CG2-CG 4.15Å; L17-T358 HydrophobicContact CD2-CG2 4.04Å; L17-V360 HydrophobicContact CD2-CG1 4.41Å
18G83.5Confident70.1Confident14 Ų1477 Ų7714%0.14441%0.413CS..PPolyproline II helixtrans-68.4172.8168.700000111.9E335 V359G18-E335 VanDerWaalsContact CA-OE1 3.31Å; G18-E335 WeakPolarHBondContact CA-OE1 3.48Å; G18-V359 WeakPolarHBondContact CA-O 3.46Å; G18-V359 PolarHBondContact N-O 3.49Å
19R84.8Confident72.7Confident76 Ų7672.3 Ų72.329%0.28740%0.398SS..  trans-99.626-177.6-70.9-166.2163.9171.44.4113.5G21 E22 E335 T338 D342R19-G21 PolarHBondContact O-N 3.48Å; R19-E22 HydrophobicContact CB-CB 4.3Å; R19-E22 HydrophobicContact CB-CG 4.25Å; R19-E22 IonicContact NE-OE2 3.13Å; R19-E22 WeakPolarHBondContact O-CB 3.44Å; R19-E22 PolarHBondContact O-N 3.48Å; R19-E335 PolarHBondContact N-OE1 2.92Å; R19-E335 PolarHBondContact N-OE2 3.06Å; R19-T338 HydrophobicContact CB-CG2 4.28Å; R19-T338 HydrophobicContact CG-CG2 4.42Å; R19-D342 IonicContact CZ-OD1 3.96Å; R19-D342 IonicContact CZ-OD2 3.5Å; R19-D342 IonicContact NE-OD2 3.74Å; R19-D342 PolarHBondContact NE-OD2 3.18Å; R19-D342 IonicContact NH1-OD1 3.47Å; R19-D342 PolarHBondContact NH1-OD1 2.72Å; R19-D342 IonicContact NH1-OD2 3.9Å; R19-D342 PolarHBondContact NH1-OD2 2.81Å; R19-D342 IonicContact NH2-OD1 3.26Å; R19-D342 IonicContact NH2-OD2 2.99Å
20E81Confident75.2Confident39 Ų3967.4 Ų67.418%0.18239%0.391CS..THydrogen-bonded Turntrans-59128.7178.6-65.8-170.2129.500111.5E22 R331 V359E20-E22 VanDerWaalsContact C-N 3.3Å; E20-R331 VanDerWaalsContact CD-NH2 3.34Å; E20-R331 WeakPolarHBondContact OE1-CB 3.43Å; E20-R331 IonicContact OE1-CZ 3.13Å; E20-R331 IonicContact OE1-NE 2.84Å; E20-R331 PolarHBondContact OE1-NE 2.66Å; E20-R331 IonicContact OE1-NH2 3.11Å; E20-R331 PolarHBondContact OE1-NH2 2.66Å; E20-R331 VanDerWaalsContact OE1-NH2 3.13Å; E20-R331 IonicContact OE2-CZ 2.66Å; E20-R331 IonicContact OE2-NE 3.75Å; E20-R331 IonicContact OE2-NH2 3.36Å; E20-R331 PolarHBondContact OE2-NH2 2.73Å; E20-V359 HydrophobicContact CG-CB 4.2Å; E20-V359 HydrophobicContact CG-CG2 4.37Å; E20-V359 VanDerWaalsContact OE1-CG2 3.23Å; E20-V359 WeakPolarHBondContact OE1-CG2 3.32Å
21G79.8Confident77.9Confident39 Ų3965.2 Ų65.240%0.40239%0.39SS..THydrogen-bonded Turntrans86.8-11.2-176.400000114.9R19 K766R19-G21 PolarHBondContact O-N 3.48Å; G21-K766 WeakPolarHBondContact CA-O 3.49Å; G21-K766 PolarHBondContact N-O 3.25Å
22E84.6Confident80.3Confident73 Ų7366.7 Ų66.734%0.34140%0.397SS..SBendtrans-73.1145.3173.2-63.1-166.9-151.300111.2R6 R19 E20 V24R6-E22 IonicContact NH1-OE2 2.82Å; R6-E22 PolarHBondContact NH1-OE2 3.35Å; R19-E22 HydrophobicContact CB-CB 4.3Å; R19-E22 HydrophobicContact CB-CG 4.25Å; R19-E22 IonicContact NE-OE2 3.13Å; R19-E22 WeakPolarHBondContact O-CB 3.44Å; R19-E22 PolarHBondContact O-N 3.48Å; E20-E22 VanDerWaalsContact C-N 3.3Å; E22-V24 PolarHBondContact O-N 3.4Å
23H81.5Confident83.1Confident125 Ų12562 Ų6258%0.57936%0.363SS*.  trans-71.9113.1174.3-176.975.2000110.2
24V84.6Confident85.4Confident22 Ų2260 Ų6013%0.13334%0.343CS..PPolyproline II helixtrans-90.6121170.7-177.20000107.7E22 M56 Y59 M60 I773E22-V24 PolarHBondContact O-N 3.4Å; V24-M56 HydrophobicContact CG1-SD 4.42Å; V24-M56 HydrophobicContact CG2-CE 4.12Å; V24-Y59 HydrophobicContact CB-CE1 4.25Å; V24-Y59 HydrophobicContact CG1-CD1 4.27Å; V24-Y59 HydrophobicContact CG1-CE1 4.05Å; V24-Y59 WeakPolarHBondContact O-CE1 3.48Å; V24-Y59 PolarHBondContact O-OH 3.29Å; V24-M60 HydrophobicContact CG1-CE 4.27Å; V24-M60 HydrophobicContact CG1-CG 3.89Å; V24-M60 HydrophobicContact CG1-SD 4.08Å; V24-I773 HydrophobicContact CB-CD1 4.24Å
25R85.4Confident87.3Confident180 Ų18057.8 Ų57.868%0.67932%0.32SS*.PPolyproline II helixtrans-76139.1174.8-72-177-178-175.70.6109.8T28R25-T28 HydrophobicContact CB-CG2 3.6Å; R25-T28 WeakPolarHBondContact O-CG2 3.5Å
26P88.1Confident88.7Confident66 Ų6657.5 Ų57.543%0.42932%0.318SS..THydrogen-bonded Turntrans-69.5153.817629.4-33.9000111.3T28 Y59P26-T28 PolarHBondContact O-N 3.34Å; P26-T28 VanDerWaalsContact O-N 3.17Å; P26-Y59 WeakPolarHBondContact CA-O 3.39Å; P26-Y59 HydrophobicContact CB-CD2 4.44Å; P26-Y59 HydrophobicContact CB-CE1 4.19Å; P26-Y59 HydrophobicContact CB-CE2 3.95Å
27L90Very high89.4Confident114 Ų11455.2 Ų55.260%0.59731%0.306SS*.THydrogen-bonded Turntrans60.319.4171.5-53.3177.4000116.6N29 T30 Y59 M60L27-N29 VanDerWaalsContact C-N 3.27Å; L27-N29 PolarHBondContact O-N 2.89Å; L27-T30 PolarHBondContact O-OG1 3.29Å; L27-Y59 PolarHBondContact N-O 3.1Å; L27-M60 CarbonylContact C-O 3.56Å; L27-M60 VanDerWaalsContact C-O 3.22Å; L27-M60 VanDerWaalsContact CA-O 3.28Å; L27-M60 WeakPolarHBondContact CA-O 3.36Å
28T89.7Confident90Very high78 Ų7851.9 Ų51.948%0.47929%0.289SS..THydrogen-bonded Turntrans-68.7-21.4-179.950.90000114.7R25 P26 M60R25-T28 HydrophobicContact CB-CG2 3.6Å; R25-T28 WeakPolarHBondContact O-CG2 3.5Å; P26-T28 PolarHBondContact O-N 3.34Å; P26-T28 VanDerWaalsContact O-N 3.17Å; T28-M60 PolarHBondContact N-O 3.44Å; T28-M60 VanDerWaalsContact N-O 3.13Å
29N92.4Very high90.5Very high29 Ų2951.6 Ų51.616%0.15528%0.284CS..THydrogen-bonded Turntrans-122.534.8-170.9-71.789000111.4L27 G31 D32 M60 M341L27-N29 VanDerWaalsContact C-N 3.27Å; L27-N29 PolarHBondContact O-N 2.89Å; N29-G31 PolarHBondContact O-N 3.3Å; N29-G31 VanDerWaalsContact O-N 3.17Å; N29-D32 HydrophobicContact CB-CB 4.4Å; N29-D32 WeakPolarHBondContact CB-OD2 3.38Å; N29-D32 PolarHBondContact ND2-OD2 3.48Å; N29-D32 WeakPolarHBondContact O-CB 3.41Å; N29-D32 PolarHBondContact O-N 3.09Å; N29-D32 VanDerWaalsContact O-N 3.11Å; N29-M60 WeakPolarHBondContact CA-O 3.46Å; N29-M60 HydrophobicContact CB-CB 4.4Å; N29-M60 PolarHBondContact N-O 2.89Å; N29-M60 VanDerWaalsContact OD1-CE 3.31Å; N29-M60 WeakPolarHBondContact OD1-CE 3.42Å; N29-M341 HydrophobicContact CB-CG 4.35Å; N29-M341 HydrophobicContact CB-SD 3.81Å; N29-M341 PolarHBondContact ND2-SD 2.98Å; N29-M341 VanDerWaalsContact ND2-SD 3.43Å
30T90.4Very high90.9Very high104 Ų10449.7 Ų49.764%0.63829%0.288SS*.THydrogen-bonded Turntrans-59.1120.6177.5-56.70000110.1L27 G61L27-T30 PolarHBondContact O-OG1 3.29Å; T30-G61 WeakPolarHBondContact CA-O 3.33Å
31G90.6Very high91.4Very high61 Ų6150 Ų5063%0.62930%0.301SS*.THydrogen-bonded Turntrans105.2-17.2-179.200000114.7N29N29-G31 PolarHBondContact O-N 3.3Å; N29-G31 VanDerWaalsContact O-N 3.17Å
32D94.9Very high92.1Very high54 Ų5450.9 Ų50.929%0.28930%0.297SS..  trans-69.3145.4171-74.5-47.2000110.7N29 C62 K63 M341N29-D32 HydrophobicContact CB-CB 4.4Å; N29-D32 WeakPolarHBondContact CB-OD2 3.38Å; N29-D32 PolarHBondContact ND2-OD2 3.48Å; N29-D32 WeakPolarHBondContact O-CB 3.41Å; N29-D32 PolarHBondContact O-N 3.09Å; N29-D32 VanDerWaalsContact O-N 3.11Å; D32-C62 HydrophobicContact CB-CB 4.47Å; D32-C62 CarbonylContact O-C 3.31Å; D32-C62 VanDerWaalsContact O-CA 3.25Å; D32-C62 WeakPolarHBondContact O-CA 3.44Å; D32-C62 WeakPolarHBondContact O-CB 3.49Å; D32-K63 PolarHBondContact O-N 3.21Å; D32-M341 HydrophobicContact CB-SD 4.06Å
33V97.6Very high92.7Very high16 Ų1647.4 Ų47.410%0.09728%0.281CS..EExtended strand (participates in β ladder)trans-123.3128.7-179.6-170.20000109.8K63 Y65 G125 I126 N128V33-K63 CarbonylContact C-O 3.34Å; V33-K63 WeakPolarHBondContact CA-O 3.35Å; V33-K63 HydrophobicContact CG1-CB 4.29Å; V33-K63 HydrophobicContact CG2-CB 4.35Å; V33-Y65 HydrophobicContact CG1-CD2 3.54Å; V33-Y65 HydrophobicContact CG1-CE2 3.64Å; V33-G125 WeakPolarHBondContact CB-O 3.34Å; V33-I126 HydrophobicContact CG1-CG1 3.78Å; V33-N128 WeakPolarHBondContact O-CB 3.47Å; V33-N128 PolarHBondContact O-N 3.36Å; V33-N128 PolarHBondContact O-ND2 2.97Å
34I98.3Very high93.4Very high0 Ų041.4 Ų41.40%025%0.253CS..EExtended strand (participates in β ladder)trans-115128.8-179.4-58.1172.8000108.7V53 C62 K63 V64 Y65 N128 V130 V337 L340 M341I34-V53 HydrophobicContact CG2-CG1 4.36Å; I34-C62 HydrophobicContact CD1-CB 3.89Å; I34-C62 HydrophobicContact CG1-CB 4.21Å; I34-K63 PolarHBondContact N-O 3.09Å; I34-V64 CarbonylContact O-C 3.48Å; I34-V64 WeakPolarHBondContact O-CA 3.25Å; I34-Y65 PolarHBondContact O-N 3.48Å; I34-N128 CarbonylContact C-O 3.58Å; I34-N128 WeakPolarHBondContact CA-O 3.36Å; I34-N128 HydrophobicContact CG1-CB 4.18Å; I34-V130 HydrophobicContact CG2-CG2 4.11Å; I34-V337 HydrophobicContact CD1-CG1 3.92Å; I34-V337 HydrophobicContact CD1-CG2 4.35Å; I34-L340 HydrophobicContact CG2-CD1 4.2Å; I34-M341 HydrophobicContact CD1-CE 3.9Å; I34-M341 HydrophobicContact CG1-CE 4.02Å
35G98.4Very high94Very high0 Ų040.4 Ų40.40%025%0.247CC..EExtended strand (participates in β ladder)trans-98.7139162.700000110.2Y65 N128 L129 V130G35-Y65 CarbonylContact C-O 3.51Å; G35-Y65 WeakPolarHBondContact CA-O 3.19Å; G35-N128 PolarHBondContact N-O 3.27Å; G35-L129 CarbonylContact O-C 3.41Å; G35-L129 WeakPolarHBondContact O-CA 3.47Å; G35-V130 PolarHBondContact O-N 2.99Å
36V98.6Very high94.6Very high0 Ų031.8 Ų31.80%021%0.214CC..EExtended strand (participates in β ladder)trans-130137.9172.6580000110.4L50 V53 V64 Y65 F66 I67 V130 I132V36-L50 HydrophobicContact CB-CD1 4.22Å; V36-L50 HydrophobicContact CG1-CD1 3.5Å; V36-L50 VanDerWaalsContact CG1-CD1 3.5Å; V36-L50 HydrophobicContact CG2-CD1 3.64Å; V36-V53 HydrophobicContact CB-CG1 3.98Å; V36-V53 HydrophobicContact CG1-CG1 4.25Å; V36-V53 HydrophobicContact CG2-CB 4.46Å; V36-V53 HydrophobicContact CG2-CG1 4.12Å; V36-V64 HydrophobicContact CG1-CG1 4.14Å; V36-Y65 PolarHBondContact N-O 2.82Å; V36-F66 HydrophobicContact CG1-CD1 3.43Å; V36-F66 VanDerWaalsContact CG1-CD1 3.43Å; V36-F66 HydrophobicContact CG1-CE1 3.63Å; V36-I67 PolarHBondContact O-N 3.32Å; V36-V130 WeakPolarHBondContact CA-O 3.48Å; V36-V130 HydrophobicContact CB-CB 4.18Å; V36-V130 HydrophobicContact CG2-CB 4Å; V36-V130 HydrophobicContact CG2-CG1 4.21Å; V36-I132 HydrophobicContact CG2-CD1 3.9Å; V36-I132 HydrophobicContact CG2-CG1 4.25Å
37F98.1Very high95.1Very high0 Ų028.7 Ų28.70%019%0.194CC..EExtended strand (participates in β ladder)trans-144.9149-177.875.3-76.4000111.2I67 Y71 M74 L129 V130 C131 I132F37-I67 HydrophobicContact CB-CB 3.8Å; F37-I67 HydrophobicContact CB-CD1 4.32Å; F37-I67 HydrophobicContact CB-CG2 4.29Å; F37-Y71 AromaticContact CE2-CD1 3.94Å; F37-Y71 HydrophobicContact CE2-CD1 3.94Å; F37-Y71 HydrophobicContact CE2-CD2 4.21Å; F37-Y71 AromaticContact CE2-CE1 3.56Å; F37-Y71 HydrophobicContact CE2-CE1 3.56Å; F37-Y71 AromaticContact CE2-CE2 3.87Å; F37-Y71 HydrophobicContact CE2-CE2 3.87Å; F37-Y71 HydrophobicContact CE2-CG 4.24Å; F37-Y71 AromaticContact CE2-CZ 3.53Å; F37-Y71 HydrophobicContact CZ-CD1 4.33Å; F37-Y71 AromaticContact CZ-CE1 3.58Å; F37-Y71 HydrophobicContact CZ-CE1 3.58Å; F37-Y71 HydrophobicContact CZ-CE2 4.39Å; F37-Y71 AromaticContact CZ-CZ 3.61Å; F37-M74 HydrophobicContact CD1-CE 3.87Å; F37-M74 HydrophobicContact CD2-CE 4.21Å; F37-M74 HydrophobicContact CE1-CE 3.84Å; F37-M74 HydrophobicContact CE2-CE 4.16Å; F37-M74 HydrophobicContact CG-CE 4.06Å; F37-M74 HydrophobicContact CZ-CE 3.97Å; F37-L129 HydrophobicContact CD1-CD1 4.01Å; F37-L129 HydrophobicContact CD1-CD2 4.29Å; F37-L129 HydrophobicContact CD1-CG 4.05Å; F37-L129 HydrophobicContact CE1-CD1 4.11Å; F37-L129 HydrophobicContact CE1-CD2 3.55Å; F37-L129 HydrophobicContact CE1-CG 3.7Å; F37-L129 HydrophobicContact CZ-CD2 4.32Å; F37-V130 VanDerWaalsContact CD1-O 3.32Å; F37-V130 WeakPolarHBondContact CD1-O 3.16Å; F37-V130 PolarHBondContact N-O 3.47Å; F37-C131 HydrophobicContact CD1-CB 4.43Å; F37-C131 HydrophobicContact CE1-CB 3.53Å; F37-C131 HydrophobicContact CE2-CB 4.49Å; F37-C131 HydrophobicContact CZ-CB 3.59Å; F37-C131 WeakPolarHBondContact CZ-SG 3.06Å; F37-I132 PolarHBondContact O-N 3.25Å
38T97.6Very high95.4Very high0 Ų023.3 Ų23.30%017%0.166CC..EExtended strand (participates in β ladder)trans-104.3133.9170.441.50000109.7M46 G70 T98 I100 G101 I132T38-M46 HydrophobicContact CG2-CB 4.19Å; T38-M46 HydrophobicContact CG2-CG 4.39Å; T38-M46 HydrophobicContact CG2-SD 3.91Å; T38-G70 WeakPolarHBondContact O-CA 3.43Å; T38-T98 WeakPolarHBondContact CG2-OG1 3.46Å; T38-T98 WeakPolarHBondContact OG1-CB 3.45Å; T38-T98 WeakPolarHBondContact OG1-CG2 3.49Å; T38-T98 PolarHBondContact OG1-OG1 3.44Å; T38-I100 HydrophobicContact CG2-CD1 4.41Å; T38-I100 HydrophobicContact CG2-CG1 4.49Å; T38-I100 VanDerWaalsContact OG1-CG1 3.24Å; T38-I100 WeakPolarHBondContact OG1-CG1 3.45Å; T38-G101 PolarHBondContact OG1-O 2.87Å; T38-I132 CarbonylContact C-O 3.56Å; T38-I132 VanDerWaalsContact CA-O 3.25Å; T38-I132 WeakPolarHBondContact CA-O 3.48Å; T38-I132 HydrophobicContact CG2-CB 3.85Å; T38-I132 HydrophobicContact CG2-CD1 4.41Å; T38-I132 HydrophobicContact CG2-CG2 4.13Å
39S95.3Very high95.8Very high8 Ų819.6 Ų19.66%0.05614%0.143CC..EExtended strand (participates in β ladder)trans-143.6142.6-178.4-176.10000112.2Y71 S102 I132 G133 S137S39-Y71 VanDerWaalsContact OG-CD2 3.31Å; S39-Y71 WeakPolarHBondContact OG-CD2 3.18Å; S39-S102 VanDerWaalsContact CA-OG 3.31Å; S39-S102 WeakPolarHBondContact CA-OG 2.8Å; S39-I132 PolarHBondContact N-O 2.95Å; S39-G133 WeakPolarHBondContact O-CA 3.39Å; S39-S137 PolarHBondContact O-OG 3.09Å; S39-S137 PolarHBondContact OG-OG 2.89Å
40G92.2Very high96.1Very high36 Ų3618.2 Ų18.237%0.37114%0.136SC..SBendtrans99.5-159.8-176.900000111.9S102G40-S102 PolarHBondContact N-OG 3.25Å; G40-S102 PolarHBondContact O-OG 3.08Å
41G92Very high96.5Very high44 Ų4413.7 Ų13.745%0.45411%0.107SC..SBendtrans-66.1136.1171.400000109.9M46G41-M46 WeakPolarHBondContact O-CE 3.48Å
42D94.5Very high96.8Very high58 Ų5810.8 Ų10.831%0.318%0.077SC..  trans-67.2154.3175.468.5-51.2000111.1M46 G97D42-M46 HydrophobicContact CB-SD 4.47Å; D42-G97 WeakPolarHBondContact OD2-CA 3.27Å
43S96.1Very high97Very high0 Ų08.2 Ų8.20%06%0.063CC..  trans-144.5148.8174.573.30000110.4G45 M46 G179 S180 I192S43-G45 PolarHBondContact O-N 3.29Å; S43-M46 VanDerWaalsContact O-CG 3.31Å; S43-M46 WeakPolarHBondContact O-CG 3.39Å; S43-M46 PolarHBondContact O-N 3.11Å; S43-G179 WeakPolarHBondContact OG-CA 3.35Å; S43-S180 PolarHBondContact OG-N 3.06Å; S43-I192 VanDerWaalsContact CB-O 3.3Å; S43-I192 WeakPolarHBondContact CB-O 3.49Å; S43-I192 PolarHBondContact OG-O 2.93Å
44Q97.1Very high97Very high0 Ų07.4 Ų7.40%06%0.059CC..THydrogen-bonded Turntrans-67.3131.4-177.4-49.890.8-33.900109.3G193 T196 Q316 R317 G318 G319 P321Q44-G193 WeakPolarHBondContact O-CA 3.45Å; Q44-G193 PolarHBondContact O-N 2.96Å; Q44-T196 HydrophobicContact CB-CG2 3.59Å; Q44-T196 HydrophobicContact CG-CG2 3.53Å; Q44-Q316 PolarHBondContact NE2-O 3.09Å; Q44-R317 WeakPolarHBondContact CG-O 3.49Å; Q44-R317 PolarHBondContact NE2-O 2.97Å; Q44-R317 VanDerWaalsContact NE2-O 3.15Å; Q44-G318 PolarHBondContact NE2-O 2.94Å; Q44-G319 WeakPolarHBondContact CG-O 3.31Å; Q44-P321 HydrophobicContact CB-CB 3.99Å
45G96.8Very high96.9Very high0 Ų08.1 Ų8.10%06%0.061CC..THydrogen-bonded Turntrans102.5-10.7-175.400000114.4S43 N47 A48 A49 I192S43-G45 PolarHBondContact O-N 3.29Å; G45-N47 PolarHBondContact O-N 3.07Å; G45-A48 WeakPolarHBondContact O-CA 3.25Å; G45-A48 WeakPolarHBondContact O-CB 3.42Å; G45-A48 PolarHBondContact O-N 3.26Å; G45-A49 PolarHBondContact O-N 3.49Å; G45-A49 VanDerWaalsContact O-N 3.1Å; G45-I192 VanDerWaalsContact C-CG2 3.49Å
46M97.8Very high96.8Very high0 Ų08.5 Ų8.50%06%0.063CC..Hα-helixtrans-54.9-40.5170.8-76-173.8173.800112.1T38 G41 D42 S43 A48 A49 L50 I132T38-M46 HydrophobicContact CG2-CB 4.19Å; T38-M46 HydrophobicContact CG2-CG 4.39Å; T38-M46 HydrophobicContact CG2-SD 3.91Å; G41-M46 WeakPolarHBondContact O-CE 3.48Å; D42-M46 HydrophobicContact CB-SD 4.47Å; S43-M46 VanDerWaalsContact O-CG 3.31Å; S43-M46 WeakPolarHBondContact O-CG 3.39Å; S43-M46 PolarHBondContact O-N 3.11Å; M46-A48 VanDerWaalsContact C-N 3.3Å; M46-A48 PolarHBondContact O-N 3.5Å; M46-A49 PolarHBondContact O-N 3.02Å; M46-L50 WeakPolarHBondContact O-CB 3.41Å; M46-L50 PolarHBondContact O-N 3.32Å; M46-I132 HydrophobicContact CB-CG2 4.47Å; M46-I132 HydrophobicContact CG-CG2 3.97Å
47N97.9Very high96.7Very high1 Ų18.5 Ų8.51%0.0056%0.063CC..Hα-helixtrans-63.3-32.4174.5-71.6-38.9000113.5G45 R51 V92 R95 S96 G97 T98 I99G45-N47 PolarHBondContact O-N 3.07Å; N47-R51 WeakPolarHBondContact O-CB 3.37Å; N47-R51 PolarHBondContact O-N 2.95Å; N47-V92 HydrophobicContact CB-CB 4.39Å; N47-V92 HydrophobicContact CB-CG2 4.36Å; N47-V92 VanDerWaalsContact CB-O 3.3Å; N47-V92 WeakPolarHBondContact CB-O 3.44Å; N47-R95 PolarHBondContact ND2-O 2.97Å; N47-S96 PolarHBondContact ND2-O 3.33Å; N47-G97 PolarHBondContact ND2-O 2.9Å; N47-G97 VanDerWaalsContact ND2-O 3.08Å; N47-T98 WeakPolarHBondContact OD1-CA 3.5Å; N47-I99 WeakPolarHBondContact OD1-CG2 3.47Å; N47-I99 PolarHBondContact OD1-N 3.22Å
48A97.8Very high96.6Very high0 Ų010.8 Ų10.80%08%0.075CC..Hα-helixtrans-68.7-41.7175.600000111G45 M46 R51 A52 I93G45-A48 WeakPolarHBondContact O-CA 3.25Å; G45-A48 WeakPolarHBondContact O-CB 3.42Å; G45-A48 PolarHBondContact O-N 3.26Å; M46-A48 VanDerWaalsContact C-N 3.3Å; M46-A48 PolarHBondContact O-N 3.5Å; A48-R51 PolarHBondContact O-N 3.27Å; A48-A52 WeakPolarHBondContact O-CB 3.25Å; A48-A52 PolarHBondContact O-N 2.93Å; A48-I93 HydrophobicContact CB-CG1 3.95Å
49A98.2Very high96.5Very high0 Ų012.2 Ų12.20%08%0.081CC..Hα-helixtrans-63.6-49.4173.200000112.3G45 M46 R51 A52 V53 I132 L177 I192 G329G45-A49 PolarHBondContact O-N 3.49Å; G45-A49 VanDerWaalsContact O-N 3.1Å; M46-A49 PolarHBondContact O-N 3.02Å; A49-R51 VanDerWaalsContact C-N 3.32Å; A49-R51 PolarHBondContact O-N 3.15Å; A49-A52 PolarHBondContact O-N 3.26Å; A49-A52 VanDerWaalsContact O-N 3.13Å; A49-V53 WeakPolarHBondContact O-CG2 3.39Å; A49-V53 PolarHBondContact O-N 3.31Å; A49-I132 HydrophobicContact CB-CD1 3.91Å; A49-L177 HydrophobicContact CB-CD1 3.91Å; A49-I192 HydrophobicContact CB-CD1 4.15Å; A49-G329 VanDerWaalsContact CA-O 3.24Å; A49-G329 WeakPolarHBondContact CA-O 3.2Å
50L98.1Very high96.5Very high0 Ų012.3 Ų12.30%08%0.08CC..Hα-helixtrans-55.8-46.3175.6-178.271000111.7V36 M46 A52 V53 C54 F66 I99 I100 I132V36-L50 HydrophobicContact CB-CD1 4.22Å; V36-L50 HydrophobicContact CG1-CD1 3.5Å; V36-L50 VanDerWaalsContact CG1-CD1 3.5Å; V36-L50 HydrophobicContact CG2-CD1 3.64Å; M46-L50 WeakPolarHBondContact O-CB 3.41Å; M46-L50 PolarHBondContact O-N 3.32Å; L50-A52 VanDerWaalsContact C-N 3.34Å; L50-A52 PolarHBondContact O-N 3.33Å; L50-V53 PolarHBondContact O-N 3.05Å; L50-C54 WeakPolarHBondContact O-CB 3.44Å; L50-C54 PolarHBondContact O-N 2.99Å; L50-F66 HydrophobicContact CD1-CD1 4.02Å; L50-F66 HydrophobicContact CD1-CE1 3.68Å; L50-F66 HydrophobicContact CD1-CZ 3.99Å; L50-F66 HydrophobicContact CD2-CE2 4.15Å; L50-F66 HydrophobicContact CD2-CZ 4.12Å; L50-F66 HydrophobicContact CG-CE1 4.1Å; L50-F66 HydrophobicContact CG-CE2 4.42Å; L50-F66 HydrophobicContact CG-CZ 3.9Å; L50-I99 HydrophobicContact CD2-CD1 3.73Å; L50-I99 HydrophobicContact CD2-CG1 3.53Å; L50-I100 HydrophobicContact CD1-CD1 3.81Å; L50-I100 HydrophobicContact CD2-CD1 4.27Å; L50-I100 HydrophobicContact CD2-CG1 4.28Å; L50-I100 HydrophobicContact CD2-CG2 3.87Å; L50-I132 HydrophobicContact CB-CD1 4.43Å
51R97.9Very high96.6Very high9 Ų911.4 Ų11.43%0.0347%0.071CC..Hα-helixtrans-58.4-44.9176.3174.8178.9173.4-82.21.1111.8N47 A48 A49 C54 R55 V89 V92 L774N47-R51 WeakPolarHBondContact O-CB 3.37Å; N47-R51 PolarHBondContact O-N 2.95Å; A48-R51 PolarHBondContact O-N 3.27Å; A49-R51 VanDerWaalsContact C-N 3.32Å; A49-R51 PolarHBondContact O-N 3.15Å; R51-C54 PolarHBondContact O-N 2.71Å; R51-R55 WeakPolarHBondContact O-CB 3.48Å; R51-R55 WeakPolarHBondContact O-CG 3.49Å; R51-R55 PolarHBondContact O-N 3.43Å; R51-V89 HydrophobicContact CB-CB 4.02Å; R51-V89 HydrophobicContact CB-CG2 4.43Å; R51-V89 HydrophobicContact CG-CB 3.98Å; R51-V89 HydrophobicContact CG-CG2 3.98Å; R51-V92 HydrophobicContact CB-CG2 4.07Å; R51-L774 PolarHBondContact NH2-O 2.9Å
52A97.6Very high96.8Very high0 Ų09.5 Ų9.50%05%0.05CC..Hα-helixtrans-68.9-40.4-179.600000112.6A48 A49 L50 C54 R55 M56 S330 A334 L774A48-A52 WeakPolarHBondContact O-CB 3.25Å; A48-A52 PolarHBondContact O-N 2.93Å; A49-A52 PolarHBondContact O-N 3.26Å; A49-A52 VanDerWaalsContact O-N 3.13Å; L50-A52 VanDerWaalsContact C-N 3.34Å; L50-A52 PolarHBondContact O-N 3.33Å; A52-C54 VanDerWaalsContact C-N 3.34Å; A52-C54 PolarHBondContact O-N 3.14Å; A52-R55 PolarHBondContact O-N 2.85Å; A52-M56 WeakPolarHBondContact O-CB 3.34Å; A52-M56 PolarHBondContact O-N 3.44Å; A52-S330 WeakPolarHBondContact CB-O 3.48Å; A52-A334 HydrophobicContact CB-CB 4.49Å; A52-L774 HydrophobicContact CB-CD1 4.23Å; A52-L774 HydrophobicContact CB-CD2 4.2Å
53V98.3Very high97Very high0 Ų012.5 Ų12.50%06%0.06CC..Hα-helixtrans-58.6-47.7173.4173.50000110.6I34 V36 A49 L50 G57 V130 L177 G333 V337I34-V53 HydrophobicContact CG2-CG1 4.36Å; V36-V53 HydrophobicContact CB-CG1 3.98Å; V36-V53 HydrophobicContact CG1-CG1 4.25Å; V36-V53 HydrophobicContact CG2-CB 4.46Å; V36-V53 HydrophobicContact CG2-CG1 4.12Å; A49-V53 WeakPolarHBondContact O-CG2 3.39Å; A49-V53 PolarHBondContact O-N 3.31Å; L50-V53 PolarHBondContact O-N 3.05Å; V53-G57 PolarHBondContact O-N 3.22Å; V53-V130 HydrophobicContact CG1-CB 4.34Å; V53-V130 HydrophobicContact CG1-CG2 3.94Å; V53-V130 HydrophobicContact CG2-CG1 3.96Å; V53-V130 HydrophobicContact CG2-CG2 4.41Å; V53-L177 HydrophobicContact CG2-CD1 4.43Å; V53-G333 WeakPolarHBondContact CG2-O 3.44Å; V53-V337 HydrophobicContact CB-CG2 4.29Å; V53-V337 HydrophobicContact CG1-CG2 3.98Å; V53-V337 WeakPolarHBondContact O-CG2 3.38Å
54C97.9Very high97.1Very high0 Ų012.5 Ų12.50%06%0.06CC..Hα-helixtrans-60.1-55.4178.1-177.80000111.8L50 R51 A52 M56 G57 L58 F66 N85 V89L50-C54 WeakPolarHBondContact O-CB 3.44Å; L50-C54 PolarHBondContact O-N 2.99Å; R51-C54 PolarHBondContact O-N 2.71Å; A52-C54 VanDerWaalsContact C-N 3.34Å; A52-C54 PolarHBondContact O-N 3.14Å; C54-M56 PolarHBondContact O-N 3.11Å; C54-G57 PolarHBondContact O-N 3.2Å; C54-L58 VanDerWaalsContact O-CG 3.26Å; C54-L58 WeakPolarHBondContact O-CG 3.48Å; C54-L58 PolarHBondContact O-N 3.45Å; C54-F66 HydrophobicContact CB-CE1 4.05Å; C54-F66 HydrophobicContact CB-CZ 4.03Å; C54-N85 PolarHBondContact SG-O 2.94Å; C54-V89 HydrophobicContact CB-CG1 3.92Å; C54-V89 HydrophobicContact CB-CG2 4.09Å
55R96.7Very high97.2Very high15 Ų1514.4 Ų14.46%0.0577%0.068CC..Hα-helixtrans-68.5-38.2-174.7-69.2-169.3175.5-163.6-4.2113R51 A52 Y59 W86 V89 S90 L774R51-R55 WeakPolarHBondContact O-CB 3.48Å; R51-R55 WeakPolarHBondContact O-CG 3.49Å; R51-R55 PolarHBondContact O-N 3.43Å; A52-R55 PolarHBondContact O-N 2.85Å; R55-Y59 VanDerWaalsContact O-CB 3.25Å; R55-Y59 WeakPolarHBondContact O-CB 3.49Å; R55-Y59 PolarHBondContact O-N 3.26Å; R55-W86 HydrophobicContact CB-CE3 4.36Å; R55-W86 HydrophobicContact CB-CH2 3.88Å; R55-W86 HydrophobicContact CB-CZ2 4.47Å; R55-W86 HydrophobicContact CB-CZ3 3.82Å; R55-W86 HydrophobicContact CG-CD2 4.18Å; R55-W86 HydrophobicContact CG-CE3 4.03Å; R55-W86 HydrophobicContact CG-CH2 3.96Å; R55-W86 HydrophobicContact CG-CZ2 4.1Å; R55-W86 HydrophobicContact CG-CZ3 3.93Å; R55-V89 HydrophobicContact CG-CG2 3.9Å; R55-S90 PolarHBondContact NH2-OG 2.98Å; R55-L774 HydrophobicContact CB-CD2 3.77Å; R55-L774 WeakPolarHBondContact CD-O 3.24Å; R55-L774 PolarHBondContact NH1-O 3.32Å
56M96.4Very high97.3Very high8 Ų814.5 Ų14.54%0.0397%0.069CC..Hα-helixtrans-68.5-41.6175.7-174.660.6112.200111.3V24 A52 C54 Y59 M60 A334 V337 L770 I773V24-M56 HydrophobicContact CG1-SD 4.42Å; V24-M56 HydrophobicContact CG2-CE 4.12Å; A52-M56 WeakPolarHBondContact O-CB 3.34Å; A52-M56 PolarHBondContact O-N 3.44Å; C54-M56 PolarHBondContact O-N 3.11Å; M56-Y59 PolarHBondContact O-N 2.88Å; M56-Y59 HydrophobicContact SD-CD1 4.29Å; M56-M60 HydrophobicContact CG-SD 4.27Å; M56-M60 WeakPolarHBondContact O-CG 3.19Å; M56-M60 PolarHBondContact O-N 2.9Å; M56-M60 HydrophobicContact SD-CG 4.33Å; M56-M60 HydrophobicContact SD-SD 4.35Å; M56-A334 HydrophobicContact CB-CB 4.32Å; M56-A334 HydrophobicContact CE-CB 3.95Å; M56-A334 HydrophobicContact CG-CB 4.35Å; M56-V337 HydrophobicContact CB-CB 4.15Å; M56-V337 HydrophobicContact CB-CG1 4.4Å; M56-V337 HydrophobicContact CB-CG2 4.08Å; M56-V337 HydrophobicContact CG-CB 3.78Å; M56-V337 HydrophobicContact CG-CG1 3.9Å; M56-V337 HydrophobicContact CG-CG2 4.28Å; M56-L770 HydrophobicContact CE-CD1 4.34Å; M56-I773 HydrophobicContact CE-CD1 4.35Å; M56-I773 HydrophobicContact SD-CG2 3.94Å
57G96.7Very high97.3Very high0 Ų014.5 Ų14.50%07%0.069CC..Hα-helixtrans-58.6-49.4175.200000112.1V53 C54 Y59 M60 G61 C62V53-G57 PolarHBondContact O-N 3.22Å; C54-G57 PolarHBondContact O-N 3.2Å; G57-Y59 VanDerWaalsContact C-N 3.34Å; G57-Y59 PolarHBondContact O-N 2.98Å; G57-M60 PolarHBondContact O-N 3.19Å; G57-G61 PolarHBondContact O-N 3.44Å; G57-C62 WeakPolarHBondContact O-CB 3.37Å; G57-C62 PolarHBondContact O-N 2.61Å
58L96.1Very high97.3Very high47 Ų4716.7 Ų16.725%0.2468%0.079CC..Hα-helixtrans-62.4-40176.6-66.9172.8000112.3C54 M60 G61 V64 W86C54-L58 VanDerWaalsContact O-CG 3.26Å; C54-L58 WeakPolarHBondContact O-CG 3.48Å; C54-L58 PolarHBondContact O-N 3.45Å; L58-M60 VanDerWaalsContact C-N 3.32Å; L58-M60 PolarHBondContact O-N 3.06Å; L58-G61 PolarHBondContact O-N 2.95Å; L58-V64 HydrophobicContact CG-CG2 4.45Å; L58-W86 HydrophobicContact CB-CE3 4.44Å; L58-W86 HydrophobicContact CD1-CB 4.41Å; L58-W86 HydrophobicContact CD1-CE3 4.2Å
59Y95.1Very high97.3Very high31 Ų3120.4 Ų20.412%0.12210%0.096CC..Hα-helixtrans-61.6-40176.8179.7-98.2000112.3V24 P26 L27 R55 M56 G57 G61 I773V24-Y59 HydrophobicContact CB-CE1 4.25Å; V24-Y59 HydrophobicContact CG1-CD1 4.27Å; V24-Y59 HydrophobicContact CG1-CE1 4.05Å; V24-Y59 WeakPolarHBondContact O-CE1 3.48Å; V24-Y59 PolarHBondContact O-OH 3.29Å; P26-Y59 WeakPolarHBondContact CA-O 3.39Å; P26-Y59 HydrophobicContact CB-CD2 4.44Å; P26-Y59 HydrophobicContact CB-CE1 4.19Å; P26-Y59 HydrophobicContact CB-CE2 3.95Å; L27-Y59 PolarHBondContact N-O 3.1Å; R55-Y59 VanDerWaalsContact O-CB 3.25Å; R55-Y59 WeakPolarHBondContact O-CB 3.49Å; R55-Y59 PolarHBondContact O-N 3.26Å; M56-Y59 PolarHBondContact O-N 2.88Å; M56-Y59 HydrophobicContact SD-CD1 4.29Å; G57-Y59 VanDerWaalsContact C-N 3.34Å; G57-Y59 PolarHBondContact O-N 2.98Å; Y59-G61 PolarHBondContact O-N 3.36Å; Y59-I773 HydrophobicContact CD1-CD1 4.31Å; Y59-I773 HydrophobicContact CD1-CG1 4.24Å; Y59-I773 HydrophobicContact CD1-CG2 3.83Å; Y59-I773 HydrophobicContact CD2-CG1 4.42Å; Y59-I773 HydrophobicContact CD2-CG2 3.99Å; Y59-I773 HydrophobicContact CE1-CD1 3.89Å; Y59-I773 HydrophobicContact CE1-CG1 3.89Å; Y59-I773 HydrophobicContact CE1-CG2 4.35Å; Y59-I773 HydrophobicContact CE2-CG1 4.07Å; Y59-I773 HydrophobicContact CE2-CG2 4.48Å; Y59-I773 HydrophobicContact CG-CG1 4.5Å; Y59-I773 HydrophobicContact CG-CG2 3.64Å
60M94.7Very high97.2Very high10 Ų1020.4 Ų20.45%0.04910%0.096CC..THydrogen-bonded Turntrans-76.9-4.1175.8-64.8-176.573.600113.3V24 L27 T28 N29 M56 G57 L58 V337 M341V24-M60 HydrophobicContact CG1-CE 4.27Å; V24-M60 HydrophobicContact CG1-CG 3.89Å; V24-M60 HydrophobicContact CG1-SD 4.08Å; L27-M60 CarbonylContact C-O 3.56Å; L27-M60 VanDerWaalsContact C-O 3.22Å; L27-M60 VanDerWaalsContact CA-O 3.28Å; L27-M60 WeakPolarHBondContact CA-O 3.36Å; T28-M60 PolarHBondContact N-O 3.44Å; T28-M60 VanDerWaalsContact N-O 3.13Å; N29-M60 WeakPolarHBondContact CA-O 3.46Å; N29-M60 HydrophobicContact CB-CB 4.4Å; N29-M60 PolarHBondContact N-O 2.89Å; N29-M60 VanDerWaalsContact OD1-CE 3.31Å; N29-M60 WeakPolarHBondContact OD1-CE 3.42Å; M56-M60 HydrophobicContact CG-SD 4.27Å; M56-M60 WeakPolarHBondContact O-CG 3.19Å; M56-M60 PolarHBondContact O-N 2.9Å; M56-M60 HydrophobicContact SD-CG 4.33Å; M56-M60 HydrophobicContact SD-SD 4.35Å; G57-M60 PolarHBondContact O-N 3.19Å; L58-M60 VanDerWaalsContact C-N 3.32Å; L58-M60 PolarHBondContact O-N 3.06Å; M60-V337 HydrophobicContact SD-CG1 3.75Å; M60-M341 HydrophobicContact CE-CB 4Å; M60-M341 HydrophobicContact CE-CG 3.81Å; M60-M341 HydrophobicContact SD-CG 4.31Å
61G95Very high97.2Very high16 Ų1621.2 Ų21.217%0.16510%0.099CC..THydrogen-bonded Turntrans91.24.5178.600000115T30 G57 L58 Y59T30-G61 WeakPolarHBondContact CA-O 3.33Å; G57-G61 PolarHBondContact O-N 3.44Å; L58-G61 PolarHBondContact O-N 2.95Å; Y59-G61 PolarHBondContact O-N 3.36Å
62C96.9Very high97.2Very high4 Ų422.3 Ų22.33%0.02710%0.104CC..  trans-73.1153.6177.8-49.10000111.2D32 I34 G57D32-C62 HydrophobicContact CB-CB 4.47Å; D32-C62 CarbonylContact O-C 3.31Å; D32-C62 VanDerWaalsContact O-CA 3.25Å; D32-C62 WeakPolarHBondContact O-CA 3.44Å; D32-C62 WeakPolarHBondContact O-CB 3.49Å; I34-C62 HydrophobicContact CD1-CB 3.89Å; I34-C62 HydrophobicContact CG1-CB 4.21Å; G57-C62 WeakPolarHBondContact O-CB 3.37Å; G57-C62 PolarHBondContact O-N 2.61Å
63K98Very high97.2Very high121 Ų12122.3 Ų22.353%0.52610%0.104SC..EExtended strand (participates in β ladder)trans-84.1132.3161.5-67.8-178.2-179.31790109.1D32 V33 I34 Y65 L83D32-K63 PolarHBondContact O-N 3.21Å; V33-K63 CarbonylContact C-O 3.34Å; V33-K63 WeakPolarHBondContact CA-O 3.35Å; V33-K63 HydrophobicContact CG1-CB 4.29Å; V33-K63 HydrophobicContact CG2-CB 4.35Å; I34-K63 PolarHBondContact N-O 3.09Å; K63-Y65 HydrophobicContact CB-CE2 4.36Å; K63-L83 HydrophobicContact CB-CD1 4.18Å
64V98.4Very high97.2Very high0 Ų022.3 Ų22.30%010%0.104CC..EExtended strand (participates in β ladder)trans-113.8127.8179.1-173.90000109.8I34 V36 L58 F66 A84I34-V64 CarbonylContact O-C 3.48Å; I34-V64 WeakPolarHBondContact O-CA 3.25Å; V36-V64 HydrophobicContact CG1-CG1 4.14Å; L58-V64 HydrophobicContact CG-CG2 4.45Å; V64-F66 HydrophobicContact CG1-CD1 4.48Å; V64-F66 HydrophobicContact CG1-CE1 4.24Å; V64-A84 PolarHBondContact O-N 2.99Å
65Y98.6Very high97.2Very high41 Ų4122.4 Ų22.416%0.16111%0.105CC..EExtended strand (participates in β ladder)trans-111.2137174.8-76.9-95.8000110.6V33 I34 G35 V36 K63 I81 T82 L83 C124 I126V33-Y65 HydrophobicContact CG1-CD2 3.54Å; V33-Y65 HydrophobicContact CG1-CE2 3.64Å; I34-Y65 PolarHBondContact O-N 3.48Å; G35-Y65 CarbonylContact C-O 3.51Å; G35-Y65 WeakPolarHBondContact CA-O 3.19Å; V36-Y65 PolarHBondContact N-O 2.82Å; K63-Y65 HydrophobicContact CB-CE2 4.36Å; Y65-I81 HydrophobicContact CD1-CG2 3.87Å; Y65-I81 HydrophobicContact CG-CG2 4.3Å; Y65-T82 CarbonylContact C-O 3.05Å; Y65-T82 WeakPolarHBondContact CA-O 3.49Å; Y65-L83 HydrophobicContact CD1-CB 4.28Å; Y65-L83 HydrophobicContact CD2-CD1 4.08Å; Y65-L83 HydrophobicContact CE1-CB 3.91Å; Y65-L83 HydrophobicContact CE1-CD1 4.17Å; Y65-L83 HydrophobicContact CE2-CD1 3.68Å; Y65-L83 HydrophobicContact CG-CD1 4.49Å; Y65-C124 HydrophobicContact CD1-CB 4.46Å; Y65-C124 HydrophobicContact CE1-CB 4.26Å; Y65-I126 HydrophobicContact CD2-CD1 4.28Å; Y65-I126 HydrophobicContact CD2-CG1 4.19Å; Y65-I126 HydrophobicContact CG-CD1 4.01Å; Y65-I126 HydrophobicContact CG-CG1 4.42Å
66F98.6Very high97.2Very high2 Ų226.1 Ų26.11%0.00912%0.123CC..EExtended strand (participates in β ladder)trans-93130.3168.8-71.4-2.1000109.2V36 L50 C54 V64 I81 T82 A84 T88 V89 I99 I100V36-F66 HydrophobicContact CG1-CD1 3.43Å; V36-F66 VanDerWaalsContact CG1-CD1 3.43Å; V36-F66 HydrophobicContact CG1-CE1 3.63Å; L50-F66 HydrophobicContact CD1-CD1 4.02Å; L50-F66 HydrophobicContact CD1-CE1 3.68Å; L50-F66 HydrophobicContact CD1-CZ 3.99Å; L50-F66 HydrophobicContact CD2-CE2 4.15Å; L50-F66 HydrophobicContact CD2-CZ 4.12Å; L50-F66 HydrophobicContact CG-CE1 4.1Å; L50-F66 HydrophobicContact CG-CE2 4.42Å; L50-F66 HydrophobicContact CG-CZ 3.9Å; C54-F66 HydrophobicContact CB-CE1 4.05Å; C54-F66 HydrophobicContact CB-CZ 4.03Å; V64-F66 HydrophobicContact CG1-CD1 4.48Å; V64-F66 HydrophobicContact CG1-CE1 4.24Å; F66-I81 CarbonylContact O-C 3.51Å; F66-I81 WeakPolarHBondContact O-CA 3.33Å; F66-T82 PolarHBondContact N-O 3.06Å; F66-T82 PolarHBondContact O-N 3.47Å; F66-A84 HydrophobicContact CD1-CB 3.68Å; F66-A84 HydrophobicContact CD2-CB 4.05Å; F66-A84 HydrophobicContact CE1-CB 3.51Å; F66-A84 HydrophobicContact CE2-CB 3.91Å; F66-A84 HydrophobicContact CG-CB 3.95Å; F66-A84 HydrophobicContact CZ-CB 3.64Å; F66-T88 HydrophobicContact CD2-CG2 4.07Å; F66-T88 HydrophobicContact CE2-CG2 3.66Å; F66-V89 HydrophobicContact CE2-CG1 3.88Å; F66-V89 HydrophobicContact CZ-CG1 3.43Å; F66-V89 VanDerWaalsContact CZ-CG1 3.43Å; F66-I99 HydrophobicContact CE2-CD1 4.44Å; F66-I100 HydrophobicContact CB-CG2 3.93Å; F66-I100 HydrophobicContact CD2-CG2 3.56Å; F66-I100 HydrophobicContact CE2-CG2 4.26Å; F66-I100 HydrophobicContact CG-CG2 3.89Å
67I98.6Very high97.2Very high0 Ų025.8 Ų25.80%012%0.122CC..EExtended strand (participates in β ladder)trans-106.5107.4173.8-53.5166.5000106.3V36 F37 M74 N80 I81 L121 L129V36-I67 PolarHBondContact O-N 3.32Å; F37-I67 HydrophobicContact CB-CB 3.8Å; F37-I67 HydrophobicContact CB-CD1 4.32Å; F37-I67 HydrophobicContact CB-CG2 4.29Å; I67-M74 HydrophobicContact CD1-CE 3.92Å; I67-M74 HydrophobicContact CD1-CG 4.48Å; I67-M74 HydrophobicContact CG2-CB 3.81Å; I67-M74 HydrophobicContact CG2-CG 4.3Å; I67-N80 CarbonylContact C-O 3.55Å; I67-N80 WeakPolarHBondContact CA-O 3.42Å; I67-I81 HydrophobicContact CG1-CG1 4.38Å; I67-I81 HydrophobicContact CG1-CG2 4.36Å; I67-I81 HydrophobicContact CG2-CG1 4.41Å; I67-L121 HydrophobicContact CD1-CD2 3.7Å; I67-L129 HydrophobicContact CD1-CD1 3.75Å
68H98.1Very high97.1Very high47 Ų4728.8 Ų28.822%0.21815%0.153CC..THydrogen-bonded Turntrans-73.5155.3-177.8-62.9-86.1000111.1G70 G73 N80 T82 I100H68-G70 PolarHBondContact O-N 2.9Å; H68-G73 WeakPolarHBondContact O-CA 3.42Å; H68-G73 PolarHBondContact O-N 2.94Å; H68-N80 PolarHBondContact CD2-O 2.85Å; H68-N80 PolarHBondContact N-O 3.43Å; H68-T82 PolarHBondContact NE2-OG1 3.1Å; H68-I100 CarbonylContact C-O 3.49Å; H68-I100 WeakPolarHBondContact CA-O 3.18Å
69E97.3Very high97.1Very high78 Ų7834 Ų3436%0.36418%0.176SC..THydrogen-bonded Turntrans54.627.6177-55.6-49.9137.600114.6Y71 Q72 I100 G101 S102 A103E69-Y71 PolarHBondContact O-N 3.37Å; E69-Q72 HydrophobicContact CB-CB 4.47Å; E69-Q72 WeakPolarHBondContact O-CB 3.48Å; E69-Q72 PolarHBondContact O-N 3.25Å; E69-I100 PolarHBondContact N-O 2.75Å; E69-G101 WeakPolarHBondContact OE1-CA 3.41Å; E69-S102 PolarHBondContact OE2-N 3.12Å; E69-A103 HydrophobicContact CB-CB 3.89Å; E69-A103 PolarHBondContact O-N 2.95Å
70G96.9Very high97.2Very high0 Ų033.2 Ų33.20%017%0.174CC..THydrogen-bonded Turntrans60.2-131.5175.800000113.5T38 H68 Q72 M74T38-G70 WeakPolarHBondContact O-CA 3.43Å; H68-G70 PolarHBondContact O-N 2.9Å; G70-Q72 PolarHBondContact O-N 3.25Å; G70-M74 PolarHBondContact O-N 3.02Å
71Y97.7Very high97.4Very high17 Ų1733.3 Ų33.37%0.06717%0.174CC..Hα-helixtrans-63.2-28.6178.5-72.8-61.4000112.6F37 S39 E69 M74 V75 F108 S137 A141F37-Y71 AromaticContact CE2-CD1 3.94Å; F37-Y71 HydrophobicContact CE2-CD1 3.94Å; F37-Y71 HydrophobicContact CE2-CD2 4.21Å; F37-Y71 AromaticContact CE2-CE1 3.56Å; F37-Y71 HydrophobicContact CE2-CE1 3.56Å; F37-Y71 AromaticContact CE2-CE2 3.87Å; F37-Y71 HydrophobicContact CE2-CE2 3.87Å; F37-Y71 HydrophobicContact CE2-CG 4.24Å; F37-Y71 AromaticContact CE2-CZ 3.53Å; F37-Y71 HydrophobicContact CZ-CD1 4.33Å; F37-Y71 AromaticContact CZ-CE1 3.58Å; F37-Y71 HydrophobicContact CZ-CE1 3.58Å; F37-Y71 HydrophobicContact CZ-CE2 4.39Å; F37-Y71 AromaticContact CZ-CZ 3.61Å; S39-Y71 VanDerWaalsContact OG-CD2 3.31Å; S39-Y71 WeakPolarHBondContact OG-CD2 3.18Å; E69-Y71 PolarHBondContact O-N 3.37Å; Y71-M74 HydrophobicContact CD1-CE 4.04Å; Y71-M74 HydrophobicContact CD1-SD 4.26Å; Y71-M74 HydrophobicContact CE1-CE 4.2Å; Y71-M74 WeakPolarHBondContact O-CB 3.44Å; Y71-M74 PolarHBondContact O-N 3.37Å; Y71-V75 WeakPolarHBondContact O-CG2 3.28Å; Y71-V75 PolarHBondContact O-N 2.98Å; Y71-F108 AromaticContact CD1-CD1 3.7Å; Y71-F108 HydrophobicContact CD1-CD1 3.7Å; Y71-F108 AromaticContact CD1-CD2 3.82Å; Y71-F108 HydrophobicContact CD1-CD2 3.82Å; Y71-F108 AromaticContact CD1-CE1 3.44Å; Y71-F108 HydrophobicContact CD1-CE1 3.44Å; Y71-F108 VanDerWaalsContact CD1-CE1 3.44Å; Y71-F108 AromaticContact CD1-CE2 3.56Å; Y71-F108 HydrophobicContact CD1-CE2 3.56Å; Y71-F108 AromaticContact CD1-CG 3.88Å; Y71-F108 HydrophobicContact CD1-CG 3.88Å; Y71-F108 AromaticContact CD1-CZ 3.36Å; Y71-F108 HydrophobicContact CD1-CZ 3.36Å; Y71-F108 HydrophobicContact CD2-CD1 4.32Å; Y71-F108 HydrophobicContact CE1-CD1 4.06Å; Y71-F108 AromaticContact CE1-CE1 3.4Å; Y71-F108 HydrophobicContact CE1-CE1 3.4Å; Y71-F108 HydrophobicContact CE1-CE2 4.09Å; Y71-F108 AromaticContact CE1-CZ 3.41Å; Y71-F108 HydrophobicContact CE1-CZ 3.41Å; Y71-F108 VanDerWaalsContact CE1-CZ 3.41Å; Y71-F108 AromaticContact CG-CD1 3.85Å; Y71-F108 HydrophobicContact CG-CD1 3.85Å; Y71-F108 HydrophobicContact CG-CD2 4.22Å; Y71-F108 HydrophobicContact CG-CE1 4.05Å; Y71-F108 HydrophobicContact CG-CE2 4.4Å; Y71-F108 AromaticContact CG-CG 3.94Å; Y71-F108 HydrophobicContact CG-CG 3.94Å; Y71-F108 HydrophobicContact CG-CZ 4.32Å; Y71-F108 AromaticContact CZ-CE1 3.98Å; Y71-S137 PolarHBondContact OH-O 2.91Å; Y71-A141 WeakPolarHBondContact OH-CA 3.39Å; Y71-A141 WeakPolarHBondContact OH-CB 3.28Å; Y71-A141 PolarHBondContact OH-N 2.94Å
72Q97.5Very high97.5Very high31 Ų3135 Ų3515%0.14518%0.181CC..Hα-helixtrans-66-50.1-178.3-1735928.700110.7E69 G70 M74 V75 E76 A103 S105 D107E69-Q72 HydrophobicContact CB-CB 4.47Å; E69-Q72 WeakPolarHBondContact O-CB 3.48Å; E69-Q72 PolarHBondContact O-N 3.25Å; G70-Q72 PolarHBondContact O-N 3.25Å; Q72-M74 PolarHBondContact O-N 3.41Å; Q72-V75 PolarHBondContact O-N 2.87Å; Q72-V75 VanDerWaalsContact O-N 3.1Å; Q72-E76 WeakPolarHBondContact CG-OE1 3.42Å; Q72-E76 PolarHBondContact NE2-OE1 3.04Å; Q72-E76 WeakPolarHBondContact O-CG 3.43Å; Q72-E76 PolarHBondContact O-N 2.99Å; Q72-A103 HydrophobicContact CB-CB 3.96Å; Q72-S105 VanDerWaalsContact OE1-CB 3.28Å; Q72-S105 PolarHBondContact OE1-OG 2.92Å; Q72-D107 PolarHBondContact NE2-OD2 3.24Å
73G97.7Very high97.6Very high0 Ų039.5 Ų39.50%021%0.205CC..Hα-helixtrans-67.7-23.717600000113.3H68 G77 N80H68-G73 WeakPolarHBondContact O-CA 3.42Å; H68-G73 PolarHBondContact O-N 2.94Å; G73-G77 PolarHBondContact O-N 2.86Å; G73-N80 WeakPolarHBondContact O-CB 3.5Å
74M98Very high97.5Very high0 Ų033.9 Ų33.90%018%0.181CC..Hα-helixtrans-63.9-43.1170-158.3-174.7-68.400111.9F37 I67 G70 Y71 Q72 F108 A117 N120 L121 L129 F144F37-M74 HydrophobicContact CD1-CE 3.87Å; F37-M74 HydrophobicContact CD2-CE 4.21Å; F37-M74 HydrophobicContact CE1-CE 3.84Å; F37-M74 HydrophobicContact CE2-CE 4.16Å; F37-M74 HydrophobicContact CG-CE 4.06Å; F37-M74 HydrophobicContact CZ-CE 3.97Å; I67-M74 HydrophobicContact CD1-CE 3.92Å; I67-M74 HydrophobicContact CD1-CG 4.48Å; I67-M74 HydrophobicContact CG2-CB 3.81Å; I67-M74 HydrophobicContact CG2-CG 4.3Å; G70-M74 PolarHBondContact O-N 3.02Å; Y71-M74 HydrophobicContact CD1-CE 4.04Å; Y71-M74 HydrophobicContact CD1-SD 4.26Å; Y71-M74 HydrophobicContact CE1-CE 4.2Å; Y71-M74 WeakPolarHBondContact O-CB 3.44Å; Y71-M74 PolarHBondContact O-N 3.37Å; Q72-M74 PolarHBondContact O-N 3.41Å; M74-F108 HydrophobicContact SD-CE2 4.21Å; M74-A117 HydrophobicContact CB-CB 4.35Å; M74-A117 HydrophobicContact CG-CB 3.87Å; M74-A117 WeakPolarHBondContact O-CA 3.45Å; M74-A117 HydrophobicContact SD-CB 4.07Å; M74-N120 PolarHBondContact O-ND2 3.08Å; M74-L121 HydrophobicContact CG-CD1 4.36Å; M74-L121 HydrophobicContact CG-CD2 4.05Å; M74-L121 HydrophobicContact CG-CG 4.13Å; M74-L121 HydrophobicContact SD-CD1 3.9Å; M74-L121 HydrophobicContact SD-CD2 4.45Å; M74-L121 HydrophobicContact SD-CG 4.33Å; M74-L129 HydrophobicContact CE-CD1 4.25Å; M74-L129 HydrophobicContact CE-CD2 4.11Å; M74-F144 HydrophobicContact SD-CE1 4.37Å; M74-F144 HydrophobicContact SD-CZ 4.49Å
75V97.9Very high97.3Very high3 Ų337.8 Ų37.82%0.01820%0.202CC..Hα-helixtrans-70.7-39.4176.8176.20000111.6Y71 Q72 D107 F108 K116 A117 N120Y71-V75 WeakPolarHBondContact O-CG2 3.28Å; Y71-V75 PolarHBondContact O-N 2.98Å; Q72-V75 PolarHBondContact O-N 2.87Å; Q72-V75 VanDerWaalsContact O-N 3.1Å; V75-D107 HydrophobicContact CG1-CB 3.97Å; V75-D107 HydrophobicContact CG2-CB 4.48Å; V75-F108 HydrophobicContact CG2-CB 4.28Å; V75-F108 HydrophobicContact CG2-CD2 3.73Å; V75-K116 HydrophobicContact CG1-CB 4.4Å; V75-K116 HydrophobicContact CG1-CD 3.99Å; V75-K116 VanDerWaalsContact O-CD 3.25Å; V75-K116 WeakPolarHBondContact O-CD 3.25Å; V75-K116 WeakPolarHBondContact O-CE 3.29Å; V75-K116 WeakPolarHBondContact O-CG 3.28Å; V75-A117 HydrophobicContact CG2-CB 4.13Å; V75-N120 VanDerWaalsContact C-ND2 3.34Å; V75-N120 PolarHBondContact O-ND2 3.22Å
76E97.3Very high96.9Very high92 Ų9239 Ų3943%0.4321%0.206SC..Hα-helixtrans-72.2-37.9-179.6-71.8173-174.900112.4Q72 N80Q72-E76 WeakPolarHBondContact CG-OE1 3.42Å; Q72-E76 PolarHBondContact NE2-OE1 3.04Å; Q72-E76 WeakPolarHBondContact O-CG 3.43Å; Q72-E76 PolarHBondContact O-N 2.99Å; E76-N80 VanDerWaalsContact CB-ND2 3.34Å; E76-N80 WeakPolarHBondContact CB-ND2 3.46Å; E76-N80 PolarHBondContact OE2-ND2 3.44Å
77G95.8Very high96.4Very high2 Ų243.5 Ų43.52%0.02123%0.23CC..  trans66.9-158.7179.200000113.4G73 H79 N80 N120G73-G77 PolarHBondContact O-N 2.86Å; G77-H79 PolarHBondContact O-N 2.9Å; G77-N80 PolarHBondContact O-N 3.34Å; G77-N120 WeakPolarHBondContact CA-ND2 3.49Å; G77-N120 PolarHBondContact N-ND2 3.25Å
78G95.4Very high96.1Very high63 Ų6346.1 Ų46.165%0.64925%0.247SC*.G310 helixtrans60.2-120.6176.100000113N80 I81G78-N80 PolarHBondContact O-N 2.98Å; G78-I81 PolarHBondContact O-N 3.34Å
79H95.4Very high95.9Very high157 Ų15743.9 Ų43.973%0.72724%0.236SC*.G310 helixtrans-65.4-16.3-177.868.5-82.6000113.8G77 I81 T82G77-H79 PolarHBondContact O-N 2.9Å; H79-I81 VanDerWaalsContact C-N 3.29Å; H79-T82 WeakPolarHBondContact O-CG2 3.38Å
80N97.9Very high95.4Very high14 Ų1442.2 Ų42.28%0.07523%0.233CC..G310 helixtrans-79.9-7.8174-69.4-42.3000113.4I67 H68 G73 E76 G77 G78I67-N80 CarbonylContact C-O 3.55Å; I67-N80 WeakPolarHBondContact CA-O 3.42Å; H68-N80 PolarHBondContact CD2-O 2.85Å; H68-N80 PolarHBondContact N-O 3.43Å; G73-N80 WeakPolarHBondContact O-CB 3.5Å; E76-N80 VanDerWaalsContact CB-ND2 3.34Å; E76-N80 WeakPolarHBondContact CB-ND2 3.46Å; E76-N80 PolarHBondContact OE2-ND2 3.44Å; G77-N80 PolarHBondContact O-N 3.34Å; G78-N80 PolarHBondContact O-N 2.98Å
81I98.5Very high95Very high11 Ų1144.6 Ų44.66%0.05625%0.246CC..EExtended strand (participates in β ladder)trans-118.292.6175.9-53.2-178.9000108.9Y65 F66 I67 G78 H79 N120 C124 I126Y65-I81 HydrophobicContact CD1-CG2 3.87Å; Y65-I81 HydrophobicContact CG-CG2 4.3Å; F66-I81 CarbonylContact O-C 3.51Å; F66-I81 WeakPolarHBondContact O-CA 3.33Å; I67-I81 HydrophobicContact CG1-CG1 4.38Å; I67-I81 HydrophobicContact CG1-CG2 4.36Å; I67-I81 HydrophobicContact CG2-CG1 4.41Å; G78-I81 PolarHBondContact O-N 3.34Å; H79-I81 VanDerWaalsContact C-N 3.29Å; I81-N120 HydrophobicContact CD1-CB 3.88Å; I81-C124 HydrophobicContact CG2-CB 4.35Å; I81-I126 HydrophobicContact CG2-CD1 3.81Å
82T98.2Very high94.8Very high51 Ų5144 Ų4431%0.31324%0.244SC..EExtended strand (participates in β ladder)trans-107.5138.8-171.460.90000112.1Y65 F66 H68 H79 A84Y65-T82 CarbonylContact C-O 3.05Å; Y65-T82 WeakPolarHBondContact CA-O 3.49Å; F66-T82 PolarHBondContact N-O 3.06Å; F66-T82 PolarHBondContact O-N 3.47Å; H68-T82 PolarHBondContact NE2-OG1 3.1Å; H79-T82 WeakPolarHBondContact O-CG2 3.38Å; T82-A84 PolarHBondContact O-N 3.39Å
83L97.8Very high94.7Very high99 Ų9942.7 Ų42.752%0.51824%0.238SC..EExtended strand (participates in β ladder)trans-67.9124.8173-174.570.6000110.1K63 Y65K63-L83 HydrophobicContact CB-CD1 4.18Å; Y65-L83 HydrophobicContact CD1-CB 4.28Å; Y65-L83 HydrophobicContact CD2-CD1 4.08Å; Y65-L83 HydrophobicContact CE1-CB 3.91Å; Y65-L83 HydrophobicContact CE1-CD1 4.17Å; Y65-L83 HydrophobicContact CE2-CD1 3.68Å; Y65-L83 HydrophobicContact CG-CD1 4.49Å
84A96.8Very high94.5Very high4 Ų444.1 Ų44.13%0.03324%0.244CC..EExtended strand (participates in β ladder)trans-91.4150.6176.100000111.2V64 F66 T82V64-A84 PolarHBondContact O-N 2.99Å; F66-A84 HydrophobicContact CD1-CB 3.68Å; F66-A84 HydrophobicContact CD2-CB 4.05Å; F66-A84 HydrophobicContact CE1-CB 3.51Å; F66-A84 HydrophobicContact CE2-CB 3.91Å; F66-A84 HydrophobicContact CG-CB 3.95Å; F66-A84 HydrophobicContact CZ-CB 3.64Å; T82-A84 PolarHBondContact O-N 3.39Å
85N93.6Very high94.4Very high82 Ų8250.5 Ų50.544%0.43927%0.268SS..  trans-130.3-178.3171.665.648.3000110.4C54 D87 T88C54-N85 PolarHBondContact SG-O 2.94Å; N85-D87 PolarHBondContact O-N 3.3Å; N85-D87 WeakPolarHBondContact OD1-CA 3.14Å; N85-D87 WeakPolarHBondContact OD1-CB 3.4Å; N85-D87 PolarHBondContact OD1-N 3.32Å; N85-T88 PolarHBondContact N-OG1 2.88Å; N85-T88 WeakPolarHBondContact O-CB 3.34Å; N85-T88 PolarHBondContact O-N 3.18Å; N85-T88 PolarHBondContact O-OG1 3.19Å; N85-T88 PolarHBondContact OD1-N 3.21Å; N85-T88 PolarHBondContact OD1-OG1 3.09Å; N85-T88 VanDerWaalsContact OD1-OG1 3.06Å
86W90.7Very high94.1Very high67 Ų6752.3 Ų52.325%0.25428%0.282SS..THydrogen-bonded Turntrans-58.3-36.8-176.7-164.4-90.1000113.5R55 L58 I773 L774 G776R55-W86 HydrophobicContact CB-CE3 4.36Å; R55-W86 HydrophobicContact CB-CH2 3.88Å; R55-W86 HydrophobicContact CB-CZ2 4.47Å; R55-W86 HydrophobicContact CB-CZ3 3.82Å; R55-W86 HydrophobicContact CG-CD2 4.18Å; R55-W86 HydrophobicContact CG-CE3 4.03Å; R55-W86 HydrophobicContact CG-CH2 3.96Å; R55-W86 HydrophobicContact CG-CZ2 4.1Å; R55-W86 HydrophobicContact CG-CZ3 3.93Å; L58-W86 HydrophobicContact CB-CE3 4.44Å; L58-W86 HydrophobicContact CD1-CB 4.41Å; L58-W86 HydrophobicContact CD1-CE3 4.2Å; W86-I773 VanDerWaalsContact CH2-O 3.27Å; W86-I773 WeakPolarHBondContact CH2-O 3.46Å; W86-L774 WeakPolarHBondContact CZ2-O 3.33Å; W86-G776 VanDerWaalsContact CZ2-N 3.33Å
87D88.3Confident93.9Very high95 Ų9548.3 Ų48.351%0.50827%0.265SS..G310 helixtrans-82-25.7-175.3-63.7-41.5000112.5N85 V89 S90N85-D87 PolarHBondContact O-N 3.3Å; N85-D87 WeakPolarHBondContact OD1-CA 3.14Å; N85-D87 WeakPolarHBondContact OD1-CB 3.4Å; N85-D87 PolarHBondContact OD1-N 3.32Å; D87-V89 PolarHBondContact O-N 3.44Å; D87-S90 WeakPolarHBondContact O-CB 3.3Å; D87-S90 PolarHBondContact O-N 3.07Å
88T91.3Very high93.9Very high56 Ų5649.4 Ų49.434%0.34427%0.271SS..G310 helixtrans-56-26.7174.9-43.40000112.5F66 N85F66-T88 HydrophobicContact CD2-CG2 4.07Å; F66-T88 HydrophobicContact CE2-CG2 3.66Å; N85-T88 PolarHBondContact N-OG1 2.88Å; N85-T88 WeakPolarHBondContact O-CB 3.34Å; N85-T88 PolarHBondContact O-N 3.18Å; N85-T88 PolarHBondContact O-OG1 3.19Å; N85-T88 PolarHBondContact OD1-N 3.21Å; N85-T88 PolarHBondContact OD1-OG1 3.09Å; N85-T88 VanDerWaalsContact OD1-OG1 3.06Å
89V93.2Very high94Very high0 Ų049.2 Ų49.20%026%0.255CS..G310 helixtrans-113.618.2179.4-62.80000113.4R51 C54 R55 F66 D87 V92R51-V89 HydrophobicContact CB-CB 4.02Å; R51-V89 HydrophobicContact CB-CG2 4.43Å; R51-V89 HydrophobicContact CG-CB 3.98Å; R51-V89 HydrophobicContact CG-CG2 3.98Å; C54-V89 HydrophobicContact CB-CG1 3.92Å; C54-V89 HydrophobicContact CB-CG2 4.09Å; R55-V89 HydrophobicContact CG-CG2 3.9Å; F66-V89 HydrophobicContact CE2-CG1 3.88Å; F66-V89 HydrophobicContact CZ-CG1 3.43Å; F66-V89 VanDerWaalsContact CZ-CG1 3.43Å; D87-V89 PolarHBondContact O-N 3.44Å; V89-V92 HydrophobicContact CB-CG2 4.08Å; V89-V92 WeakPolarHBondContact O-CG2 3.42Å
90S88.7Confident94.1Very high42 Ų4241.9 Ų41.929%0.29422%0.221SC..THydrogen-bonded Turntrans-73.2136170.8-73.20000110.1R55 D87 V92R55-S90 PolarHBondContact NH2-OG 2.98Å; D87-S90 WeakPolarHBondContact O-CB 3.3Å; D87-S90 PolarHBondContact O-N 3.07Å; S90-V92 VanDerWaalsContact C-N 3.26Å; S90-V92 WeakPolarHBondContact O-CG1 3.39Å; S90-V92 PolarHBondContact O-N 3.38Å
91D86.9Confident94Very high51 Ų5142 Ų4227%0.27323%0.225SC..THydrogen-bonded Turntrans58.729.8176.8-64.8-2.5000116.1Q94 R95 R643D91-Q94 PolarHBondContact O-NE2 3.44Å; D91-Q94 VanDerWaalsContact O-NE2 3.11Å; D91-R95 PolarHBondContact O-NE 2.9Å; D91-R95 VanDerWaalsContact O-NE 3.1Å; D91-R643 IonicContact OD1-CZ 2.69Å; D91-R643 VanDerWaalsContact OD1-CZ 3.22Å; D91-R643 IonicContact OD1-NE 3.72Å; D91-R643 PolarHBondContact OD1-NE 3.31Å; D91-R643 IonicContact OD1-NH2 2.94Å; D91-R643 PolarHBondContact OD1-NH2 2.84Å; D91-R643 IonicContact OD2-CZ 3.1Å; D91-R643 IonicContact OD2-NE 2.71Å; D91-R643 PolarHBondContact OD2-NE 2.81Å; D91-R643 IonicContact OD2-NH2 3.53Å
92V93.8Very high93.8Very high5 Ų543 Ų433%0.0323%0.234CC..  trans-103.5-15.7175.5-50.60000113.9N47 R51 V89 S90 Q94 R95 I99N47-V92 HydrophobicContact CB-CB 4.39Å; N47-V92 HydrophobicContact CB-CG2 4.36Å; N47-V92 VanDerWaalsContact CB-O 3.3Å; N47-V92 WeakPolarHBondContact CB-O 3.44Å; R51-V92 HydrophobicContact CB-CG2 4.07Å; V89-V92 HydrophobicContact CB-CG2 4.08Å; V89-V92 WeakPolarHBondContact O-CG2 3.42Å; S90-V92 VanDerWaalsContact C-N 3.26Å; S90-V92 WeakPolarHBondContact O-CG1 3.39Å; S90-V92 PolarHBondContact O-N 3.38Å; V92-Q94 PolarHBondContact O-N 2.92Å; V92-R95 WeakPolarHBondContact O-CB 3.32Å; V92-R95 PolarHBondContact O-N 3.22Å; V92-I99 HydrophobicContact CB-CD1 4.25Å; V92-I99 HydrophobicContact CB-CG2 4.25Å; V92-I99 HydrophobicContact CG1-CD1 3.82Å; V92-I99 HydrophobicContact CG1-CG2 4.09Å; V92-I99 HydrophobicContact CG2-CD1 4.36Å
93I95.5Very high93.5Very high2 Ų242 Ų421%0.0123%0.231CC..THydrogen-bonded Turntrans-60.4-32.3-172.9-167166000113.4A48 P321 R326 L607 A608A48-I93 HydrophobicContact CB-CG1 3.95Å; I93-P321 WeakPolarHBondContact O-CG 3.5Å; I93-R326 HydrophobicContact CG1-CB 4.29Å; I93-R326 HydrophobicContact CG1-CG 4.27Å; I93-L607 WeakPolarHBondContact CD1-O 3.32Å; I93-A608 VanDerWaalsContact CD1-O 3.24Å; I93-A608 WeakPolarHBondContact CD1-O 3.48Å
94Q94.5Very high93.1Very high30 Ų3049.1 Ų49.114%0.1425%0.25CS..THydrogen-bonded Turntrans-91.6-1177.773.8-76.8-3.800114.2D91 V92 N320 P321 D575D91-Q94 PolarHBondContact O-NE2 3.44Å; D91-Q94 VanDerWaalsContact O-NE2 3.11Å; V92-Q94 PolarHBondContact O-N 2.92Å; Q94-N320 VanDerWaalsContact O-CG 3.3Å; Q94-N320 PolarHBondContact O-OD1 3.03Å; Q94-P321 WeakPolarHBondContact O-CD 3.38Å; Q94-D575 WeakPolarHBondContact CB-OD1 3.25Å; Q94-D575 WeakPolarHBondContact CB-OD2 3.3Å
95R94.3Very high92.9Very high134 Ų13449.4 Ų49.451%0.50625%0.252SS..  trans-84.2135.5-178-63.1-174.9-174.8-157.4-3110.6N47 D91 V92N47-R95 PolarHBondContact ND2-O 2.97Å; D91-R95 PolarHBondContact O-NE 2.9Å; D91-R95 VanDerWaalsContact O-NE 3.1Å; V92-R95 WeakPolarHBondContact O-CB 3.32Å; V92-R95 PolarHBondContact O-N 3.22Å
96S91.3Very high92.8Very high42 Ų4254 Ų5429%0.29427%0.268SS..SBendtrans-65.3165.2170-165.10000112.1N47 G319N47-S96 PolarHBondContact ND2-O 3.33Å; S96-G319 WeakPolarHBondContact CB-O 3.42Å; S96-G319 PolarHBondContact OG-N 3.42Å; S96-G319 PolarHBondContact OG-O 3.4Å; S96-G319 VanDerWaalsContact OG-O 3.07Å
97G94.4Very high93Very high8 Ų854.4 Ų54.48%0.08228%0.275CS..SBendtrans63.2-143.8176.200000112.6D42 N47D42-G97 WeakPolarHBondContact OD2-CA 3.27Å; N47-G97 PolarHBondContact ND2-O 2.9Å; N47-G97 VanDerWaalsContact ND2-O 3.08Å
98T96.4Very high93.3Very high25 Ų2550.7 Ų50.715%0.15326%0.255CS..  trans-134.9130.2178.1173.60000110.9T38 N47 I100 G101T38-T98 WeakPolarHBondContact CG2-OG1 3.46Å; T38-T98 WeakPolarHBondContact OG1-CB 3.45Å; T38-T98 WeakPolarHBondContact OG1-CG2 3.49Å; T38-T98 PolarHBondContact OG1-OG1 3.44Å; N47-T98 WeakPolarHBondContact OD1-CA 3.5Å; T98-I100 PolarHBondContact O-N 3.15Å; T98-I100 WeakPolarHBondContact OG1-CG1 3.5Å; T98-I100 PolarHBondContact OG1-N 3.42Å; T98-G101 VanDerWaalsContact CG2-O 3.31Å; T98-G101 WeakPolarHBondContact CG2-O 3.37Å; T98-G101 PolarHBondContact O-N 2.92Å
99I96.6Very high93.4Very high59 Ų5957.4 Ų57.430%0.30328%0.275SS..THydrogen-bonded Turntrans-70.2-13.1178.866.3-178.8000113.5N47 L50 F66 V92N47-I99 WeakPolarHBondContact OD1-CG2 3.47Å; N47-I99 PolarHBondContact OD1-N 3.22Å; L50-I99 HydrophobicContact CD2-CD1 3.73Å; L50-I99 HydrophobicContact CD2-CG1 3.53Å; F66-I99 HydrophobicContact CE2-CD1 4.44Å; V92-I99 HydrophobicContact CB-CD1 4.25Å; V92-I99 HydrophobicContact CB-CG2 4.25Å; V92-I99 HydrophobicContact CG1-CD1 3.82Å; V92-I99 HydrophobicContact CG1-CG2 4.09Å; V92-I99 HydrophobicContact CG2-CD1 4.36Å
100I97.5Very high93.5Very high2 Ų260.5 Ų60.51%0.0129%0.294CS..THydrogen-bonded Turntrans-105.39.2178.764.5174.3000112.1T38 L50 F66 H68 E69 T98T38-I100 HydrophobicContact CG2-CD1 4.41Å; T38-I100 HydrophobicContact CG2-CG1 4.49Å; T38-I100 VanDerWaalsContact OG1-CG1 3.24Å; T38-I100 WeakPolarHBondContact OG1-CG1 3.45Å; L50-I100 HydrophobicContact CD1-CD1 3.81Å; L50-I100 HydrophobicContact CD2-CD1 4.27Å; L50-I100 HydrophobicContact CD2-CG1 4.28Å; L50-I100 HydrophobicContact CD2-CG2 3.87Å; F66-I100 HydrophobicContact CB-CG2 3.93Å; F66-I100 HydrophobicContact CD2-CG2 3.56Å; F66-I100 HydrophobicContact CE2-CG2 4.26Å; F66-I100 HydrophobicContact CG-CG2 3.89Å; H68-I100 CarbonylContact C-O 3.49Å; H68-I100 WeakPolarHBondContact CA-O 3.18Å; E69-I100 PolarHBondContact N-O 2.75Å; T98-I100 PolarHBondContact O-N 3.15Å; T98-I100 WeakPolarHBondContact OG1-CG1 3.5Å; T98-I100 PolarHBondContact OG1-N 3.42Å
101G96.2Very high93.8Very high16 Ų1662.5 Ų62.517%0.16531%0.306CS..  trans68176.817900000114.6T38 E69 T98T38-G101 PolarHBondContact OG1-O 2.87Å; E69-G101 WeakPolarHBondContact OE1-CA 3.41Å; T98-G101 VanDerWaalsContact CG2-O 3.31Å; T98-G101 WeakPolarHBondContact CG2-O 3.37Å; T98-G101 PolarHBondContact O-N 2.92Å
102S94.3Very high94.3Very high34 Ų3465.1 Ų65.124%0.23832%0.317CS..  trans-162.697.4179.2-177.90000109.2S39 G40 E69S39-S102 VanDerWaalsContact CA-OG 3.31Å; S39-S102 WeakPolarHBondContact CA-OG 2.8Å; G40-S102 PolarHBondContact N-OG 3.25Å; G40-S102 PolarHBondContact O-OG 3.08Å; E69-S102 PolarHBondContact OE2-N 3.12Å
103A91.6Very high94.4Very high30 Ų3065.1 Ų65.125%0.24832%0.317CS..  trans-99.6151.3178.200000111.7E69 Q72E69-A103 HydrophobicContact CB-CB 3.89Å; E69-A103 PolarHBondContact O-N 2.95Å; Q72-A103 HydrophobicContact CB-CB 3.96Å
104R89Confident94.5Very high247 Ų24766.1 Ų66.193%0.93232%0.321SS*.  trans-74.2126.8164.8-63.7-173-160.4176.36108.3
105S92.7Very high94.6Very high10 Ų1065.2 Ų65.27%0.0732%0.317CS..  trans-104.4113.8175-174.10000110.6Q72 F108 Y109Q72-S105 VanDerWaalsContact OE1-CB 3.28Å; Q72-S105 PolarHBondContact OE1-OG 2.92Å; S105-F108 PolarHBondContact OG-N 2.94Å; S105-Y109 WeakPolarHBondContact O-CD2 3.37Å; S105-Y109 WeakPolarHBondContact O-CE2 3.36Å
106K92.5Very high94.8Very high180 Ų18064 Ų6478%0.78332%0.316SS*.SBendtrans-72.9-38.8169.5-69.8-176.4-178.5178.40110.5F108 Y109K106-F108 VanDerWaalsContact C-N 3.27Å; K106-F108 PolarHBondContact O-N 3.21Å; K106-Y109 WeakPolarHBondContact O-CB 3.32Å; K106-Y109 PolarHBondContact O-N 3.45Å; K106-Y109 VanDerWaalsContact O-N 3.1Å
107D93.7Very high95.1Very high75 Ų7562 Ų6240%0.40130%0.302SS..G310 helixtrans-59.4-38.9-177.6-58.3-17.6000111.7Q72 V75 Y109 T110 G113Q72-D107 PolarHBondContact NE2-OD2 3.24Å; V75-D107 HydrophobicContact CG1-CB 3.97Å; V75-D107 HydrophobicContact CG2-CB 4.48Å; D107-Y109 PolarHBondContact O-N 3.47Å; D107-Y109 VanDerWaalsContact O-N 3.16Å; D107-T110 WeakPolarHBondContact O-CB 3.39Å; D107-T110 PolarHBondContact O-N 2.98Å; D107-T110 PolarHBondContact O-OG1 3.03Å; D107-G113 WeakPolarHBondContact O-CA 3.49Å
108F95.5Very high95.2Very high16 Ų1661.7 Ų61.77%0.0730%0.298CS..G310 helixtrans-65.9-17-179.6-155.8-98.7000114.2Y71 M74 V75 S105 K106 T110 R114 A117 F144Y71-F108 AromaticContact CD1-CD1 3.7Å; Y71-F108 HydrophobicContact CD1-CD1 3.7Å; Y71-F108 AromaticContact CD1-CD2 3.82Å; Y71-F108 HydrophobicContact CD1-CD2 3.82Å; Y71-F108 AromaticContact CD1-CE1 3.44Å; Y71-F108 HydrophobicContact CD1-CE1 3.44Å; Y71-F108 VanDerWaalsContact CD1-CE1 3.44Å; Y71-F108 AromaticContact CD1-CE2 3.56Å; Y71-F108 HydrophobicContact CD1-CE2 3.56Å; Y71-F108 AromaticContact CD1-CG 3.88Å; Y71-F108 HydrophobicContact CD1-CG 3.88Å; Y71-F108 AromaticContact CD1-CZ 3.36Å; Y71-F108 HydrophobicContact CD1-CZ 3.36Å; Y71-F108 HydrophobicContact CD2-CD1 4.32Å; Y71-F108 HydrophobicContact CE1-CD1 4.06Å; Y71-F108 AromaticContact CE1-CE1 3.4Å; Y71-F108 HydrophobicContact CE1-CE1 3.4Å; Y71-F108 HydrophobicContact CE1-CE2 4.09Å; Y71-F108 AromaticContact CE1-CZ 3.41Å; Y71-F108 HydrophobicContact CE1-CZ 3.41Å; Y71-F108 VanDerWaalsContact CE1-CZ 3.41Å; Y71-F108 AromaticContact CG-CD1 3.85Å; Y71-F108 HydrophobicContact CG-CD1 3.85Å; Y71-F108 HydrophobicContact CG-CD2 4.22Å; Y71-F108 HydrophobicContact CG-CE1 4.05Å; Y71-F108 HydrophobicContact CG-CE2 4.4Å; Y71-F108 AromaticContact CG-CG 3.94Å; Y71-F108 HydrophobicContact CG-CG 3.94Å; Y71-F108 HydrophobicContact CG-CZ 4.32Å; Y71-F108 AromaticContact CZ-CE1 3.98Å; M74-F108 HydrophobicContact SD-CE2 4.21Å; V75-F108 HydrophobicContact CG2-CB 4.28Å; V75-F108 HydrophobicContact CG2-CD2 3.73Å; S105-F108 PolarHBondContact OG-N 2.94Å; K106-F108 VanDerWaalsContact C-N 3.27Å; K106-F108 PolarHBondContact O-N 3.21Å; F108-T110 PolarHBondContact O-N 3.48Å; F108-R114 HydrophobicContact CD1-CG 4.18Å; F108-R114 HydrophobicContact CD2-CG 4.07Å; F108-R114 HydrophobicContact CE1-CG 4.14Å; F108-R114 HydrophobicContact CE2-CG 4.05Å; F108-R114 HydrophobicContact CG-CG 4.15Å; F108-R114 HydrophobicContact CZ-CG 4.08Å; F108-R114 WeakPolarHBondContact O-CD 3.18Å; F108-R114 WeakPolarHBondContact O-CG 3.4Å; F108-R114 PolarHBondContact O-NH1 2.95Å; F108-R114 VanDerWaalsContact O-NH1 3.11Å; F108-A117 HydrophobicContact CD2-CB 4.14Å; F108-A117 HydrophobicContact CE2-CB 3.7Å; F108-F144 HydrophobicContact CE1-CB 4.42Å; F108-F144 HydrophobicContact CE1-CD2 4.4Å; F108-F144 HydrophobicContact CE2-CD2 4Å; F108-F144 HydrophobicContact CE2-CE2 4.01Å; F108-F144 HydrophobicContact CZ-CB 4.04Å; F108-F144 HydrophobicContact CZ-CD1 4.41Å; F108-F144 AromaticContact CZ-CD2 3.48Å; F108-F144 HydrophobicContact CZ-CD2 3.48Å; F108-F144 VanDerWaalsContact CZ-CD2 3.48Å; F108-F144 AromaticContact CZ-CE2 3.95Å; F108-F144 HydrophobicContact CZ-CE2 3.95Å; F108-F144 AromaticContact CZ-CG 3.74Å; F108-F144 HydrophobicContact CZ-CG 3.74Å
109Y93.3Very high95.3Very high197 Ų19764.8 Ų64.877%0.77331%0.307SS*.G310 helixtrans-71.3-20.7170.3-73.3-89.9000112.4S105 K106 D107 R114S105-Y109 WeakPolarHBondContact O-CD2 3.37Å; S105-Y109 WeakPolarHBondContact O-CE2 3.36Å; K106-Y109 WeakPolarHBondContact O-CB 3.32Å; K106-Y109 PolarHBondContact O-N 3.45Å; K106-Y109 VanDerWaalsContact O-N 3.1Å; D107-Y109 PolarHBondContact O-N 3.47Å; D107-Y109 VanDerWaalsContact O-N 3.16Å; Y109-R114 PolarHBondContact O-NH1 3.33Å
110T95.3Very high95.3Very high65 Ų6562.9 Ų62.940%0.39930%0.298SS..SBendtrans-90.3145.7178.471.70000111.5D107 F108 E112 G113 R114D107-T110 WeakPolarHBondContact O-CB 3.39Å; D107-T110 PolarHBondContact O-N 2.98Å; D107-T110 PolarHBondContact O-OG1 3.03Å; F108-T110 PolarHBondContact O-N 3.48Å; T110-E112 VanDerWaalsContact C-N 3.32Å; T110-E112 PolarHBondContact O-N 3.24Å; T110-G113 PolarHBondContact O-N 3.44Å; T110-G113 PolarHBondContact OG1-N 2.56Å; T110-R114 PolarHBondContact O-N 3.01Å; T110-R114 PolarHBondContact O-NH1 3.24Å
111P95Very high95.3Very high84 Ų8462.8 Ų62.855%0.54530%0.297SS..Hα-helixtrans-54.5-44.6172-26.335.6000112.9G113 R114 L115P111-G113 PolarHBondContact O-N 2.84Å; P111-R114 PolarHBondContact O-N 3.04Å; P111-R114 VanDerWaalsContact O-N 3.16Å; P111-L115 WeakPolarHBondContact O-CB 3.49Å; P111-L115 PolarHBondContact O-N 3.33Å
112E96.1Very high95.3Very high107 Ų10762 Ų6250%0.529%0.289SS..Hα-helixtrans-54.4-45.5174.5-98.859.9-147.300113.4T110 R114 L115 K116 R158T110-E112 VanDerWaalsContact C-N 3.32Å; T110-E112 PolarHBondContact O-N 3.24Å; E112-R114 VanDerWaalsContact C-N 3.35Å; E112-R114 PolarHBondContact O-N 3.15Å; E112-L115 WeakPolarHBondContact O-CB 3.16Å; E112-L115 PolarHBondContact O-N 3.07Å; E112-K116 WeakPolarHBondContact O-CB 3.37Å; E112-K116 PolarHBondContact O-N 2.71Å; E112-R158 IonicContact OE1-NH2 3.81Å; E112-R158 PolarHBondContact OE1-NH2 3.35Å
113G96.9Very high95.3Very high4 Ų463.4 Ų63.44%0.04130%0.299CS..Hα-helixtrans-63.4-41.5177.800000112D107 T110 P111 K116 A117D107-G113 WeakPolarHBondContact O-CA 3.49Å; T110-G113 PolarHBondContact O-N 3.44Å; T110-G113 PolarHBondContact OG1-N 2.56Å; P111-G113 PolarHBondContact O-N 2.84Å; G113-K116 PolarHBondContact O-N 3.38Å; G113-A117 PolarHBondContact O-N 2.96Å
114R97.5Very high95.5Very high24 Ų2463.7 Ų63.79%0.09130%0.298CS..Hα-helixtrans-65.7-40.7175.1-64.9-169.1-62.5-89.612.4111.8F108 Y109 T110 P111 E112 K116 A117 A118 F144 E147 M151F108-R114 HydrophobicContact CD1-CG 4.18Å; F108-R114 HydrophobicContact CD2-CG 4.07Å; F108-R114 HydrophobicContact CE1-CG 4.14Å; F108-R114 HydrophobicContact CE2-CG 4.05Å; F108-R114 HydrophobicContact CG-CG 4.15Å; F108-R114 HydrophobicContact CZ-CG 4.08Å; F108-R114 WeakPolarHBondContact O-CD 3.18Å; F108-R114 WeakPolarHBondContact O-CG 3.4Å; F108-R114 PolarHBondContact O-NH1 2.95Å; F108-R114 VanDerWaalsContact O-NH1 3.11Å; Y109-R114 PolarHBondContact O-NH1 3.33Å; T110-R114 PolarHBondContact O-N 3.01Å; T110-R114 PolarHBondContact O-NH1 3.24Å; P111-R114 PolarHBondContact O-N 3.04Å; P111-R114 VanDerWaalsContact O-N 3.16Å; E112-R114 VanDerWaalsContact C-N 3.35Å; E112-R114 PolarHBondContact O-N 3.15Å; R114-K116 VanDerWaalsContact C-N 3.32Å; R114-K116 PolarHBondContact O-N 3.21Å; R114-A117 WeakPolarHBondContact O-CB 3.27Å; R114-A117 PolarHBondContact O-N 3.37Å; R114-A118 PolarHBondContact O-N 3.06Å; R114-F144 HydrophobicContact CB-CD2 4.05Å; R114-F144 HydrophobicContact CB-CE2 4.05Å; R114-F144 HydrophobicContact CG-CD2 4.25Å; R114-F144 WeakPolarHBondContact O-CE2 3.39Å; R114-E147 IonicContact CZ-OE1 3.33Å; R114-E147 IonicContact CZ-OE2 2.71Å; R114-E147 IonicContact NE-OE1 3.09Å; R114-E147 IonicContact NE-OE2 3.61Å; R114-E147 PolarHBondContact NE-OE2 2.91Å; R114-E147 IonicContact NH2-OE1 3.32Å; R114-E147 PolarHBondContact NH2-OE1 3.39Å; R114-E147 IonicContact NH2-OE2 3.82Å; R114-E147 PolarHBondContact NH2-OE2 3.08Å; R114-M151 VanDerWaalsContact C-SD 3.53Å; R114-M151 HydrophobicContact CB-SD 3.84Å
115L97.2Very high95.8Very high10 Ų1052.7 Ų52.75%0.05226%0.262CS..Hα-helixtrans-58.8-43.8174.8-167.972.8000111.5P111 E112 A118 Y119 M151 E154 L155P111-L115 WeakPolarHBondContact O-CB 3.49Å; P111-L115 PolarHBondContact O-N 3.33Å; E112-L115 WeakPolarHBondContact O-CB 3.16Å; E112-L115 PolarHBondContact O-N 3.07Å; L115-A118 PolarHBondContact O-N 2.97Å; L115-Y119 PolarHBondContact O-N 3.44Å; L115-M151 HydrophobicContact CD1-CB 3.88Å; L115-M151 HydrophobicContact CD1-CG 4.03Å; L115-E154 HydrophobicContact CD1-CB 4.03Å; L115-E154 HydrophobicContact CD1-CG 4.08Å; L115-E154 HydrophobicContact CD2-CG 4.03Å; L115-L155 HydrophobicContact CD1-CD1 4.41Å; L115-L155 HydrophobicContact CD1-CD2 4.01Å; L115-L155 HydrophobicContact CD1-CG 3.71Å; L115-L155 HydrophobicContact CD2-CD2 4.4Å; L115-L155 HydrophobicContact CG-CD2 3.85Å; L115-L155 HydrophobicContact CG-CG 4.13Å
116K97.4Very high96Very high110 Ų11052.2 Ų52.248%0.47826%0.258SS..Hα-helixtrans-65-41.9176.2-166.4179.1176.8-173.60112V75 E112 G113 R114 Y119 N120V75-K116 HydrophobicContact CG1-CB 4.4Å; V75-K116 HydrophobicContact CG1-CD 3.99Å; V75-K116 VanDerWaalsContact O-CD 3.25Å; V75-K116 WeakPolarHBondContact O-CD 3.25Å; V75-K116 WeakPolarHBondContact O-CE 3.29Å; V75-K116 WeakPolarHBondContact O-CG 3.28Å; E112-K116 WeakPolarHBondContact O-CB 3.37Å; E112-K116 PolarHBondContact O-N 2.71Å; G113-K116 PolarHBondContact O-N 3.38Å; R114-K116 VanDerWaalsContact C-N 3.32Å; R114-K116 PolarHBondContact O-N 3.21Å; K116-Y119 WeakPolarHBondContact O-CB 3.47Å; K116-Y119 PolarHBondContact O-N 3.29Å; K116-N120 VanDerWaalsContact O-CG 3.26Å; K116-N120 PolarHBondContact O-N 3.43Å; K116-N120 PolarHBondContact O-ND2 3.38Å
117A97.7Very high96.1Very high0 Ų045.1 Ų45.10%023%0.229CC..Hα-helixtrans-60.3-45.1173.800000112.1M74 V75 F108 G113 R114 Y119 N120 L121 F144M74-A117 HydrophobicContact CB-CB 4.35Å; M74-A117 HydrophobicContact CG-CB 3.87Å; M74-A117 WeakPolarHBondContact O-CA 3.45Å; M74-A117 HydrophobicContact SD-CB 4.07Å; V75-A117 HydrophobicContact CG2-CB 4.13Å; F108-A117 HydrophobicContact CD2-CB 4.14Å; F108-A117 HydrophobicContact CE2-CB 3.7Å; G113-A117 PolarHBondContact O-N 2.96Å; R114-A117 WeakPolarHBondContact O-CB 3.27Å; R114-A117 PolarHBondContact O-N 3.37Å; A117-Y119 VanDerWaalsContact C-N 3.34Å; A117-Y119 PolarHBondContact O-N 2.76Å; A117-N120 PolarHBondContact O-N 3.03Å; A117-L121 WeakPolarHBondContact O-CG 3.35Å; A117-L121 PolarHBondContact O-N 3.39Å; A117-F144 HydrophobicContact CB-CE2 4.21Å; A117-F144 HydrophobicContact CB-CZ 4.17Å
118A97.6Very high96.2Very high0 Ų041.6 Ų41.60%021%0.21CC..Hα-helixtrans-60.4-43.5176.600000111.8R114 L115 N120 L121 L122 F144 W148 M151 L155R114-A118 PolarHBondContact O-N 3.06Å; L115-A118 PolarHBondContact O-N 2.97Å; A118-N120 PolarHBondContact O-N 3.3Å; A118-L121 PolarHBondContact O-N 3.12Å; A118-L122 WeakPolarHBondContact O-CB 3.26Å; A118-L122 WeakPolarHBondContact O-CD1 3.28Å; A118-L122 VanDerWaalsContact O-CG 3.27Å; A118-L122 WeakPolarHBondContact O-CG 3.27Å; A118-L122 PolarHBondContact O-N 3.1Å; A118-F144 HydrophobicContact CB-CE2 4.33Å; A118-F144 HydrophobicContact CB-CZ 4.03Å; A118-W148 HydrophobicContact CB-CE3 4.2Å; A118-W148 HydrophobicContact CB-CH2 4.21Å; A118-W148 HydrophobicContact CB-CZ3 3.7Å; A118-M151 HydrophobicContact CB-CB 4.31Å; A118-M151 HydrophobicContact CB-CE 4.15Å; A118-M151 HydrophobicContact CB-SD 3.98Å; A118-L155 HydrophobicContact CB-CD1 4.23Å
119Y97.4Very high96.3Very high91 Ų9140.8 Ų40.836%0.35721%0.207SC..Hα-helixtrans-57.4-48.4174173.3-101.1000112.2L115 K116 A117 L121 L122 C123 L155 S160 I161L115-Y119 PolarHBondContact O-N 3.44Å; K116-Y119 WeakPolarHBondContact O-CB 3.47Å; K116-Y119 PolarHBondContact O-N 3.29Å; A117-Y119 VanDerWaalsContact C-N 3.34Å; A117-Y119 PolarHBondContact O-N 2.76Å; Y119-L121 PolarHBondContact O-N 3.19Å; Y119-L122 WeakPolarHBondContact O-CB 3.39Å; Y119-L122 PolarHBondContact O-N 2.87Å; Y119-C123 PolarHBondContact O-N 3.01Å; Y119-C123 PolarHBondContact O-SG 3.48Å; Y119-C123 VanDerWaalsContact O-SG 3.33Å; Y119-L155 HydrophobicContact CD2-CD2 4.41Å; Y119-S160 WeakPolarHBondContact CE2-O 3.29Å; Y119-I161 HydrophobicContact CD2-CG2 4.03Å; Y119-I161 HydrophobicContact CE2-CG2 4.37Å
120N97.8Very high96.5Very high18 Ų1831.4 Ų31.410%0.09617%0.17CC..Hα-helixtrans-63.7-41.7-178.9-67.2-27.8000112.6M74 V75 G77 I81 K116 A117 A118 L122 C123 C124M74-N120 PolarHBondContact O-ND2 3.08Å; V75-N120 VanDerWaalsContact C-ND2 3.34Å; V75-N120 PolarHBondContact O-ND2 3.22Å; G77-N120 WeakPolarHBondContact CA-ND2 3.49Å; G77-N120 PolarHBondContact N-ND2 3.25Å; I81-N120 HydrophobicContact CD1-CB 3.88Å; K116-N120 VanDerWaalsContact O-CG 3.26Å; K116-N120 PolarHBondContact O-N 3.43Å; K116-N120 PolarHBondContact O-ND2 3.38Å; A117-N120 PolarHBondContact O-N 3.03Å; A118-N120 PolarHBondContact O-N 3.3Å; N120-L122 VanDerWaalsContact C-N 3.34Å; N120-L122 PolarHBondContact O-N 3.17Å; N120-C123 WeakPolarHBondContact O-CB 3.06Å; N120-C123 PolarHBondContact O-N 3.44Å; N120-C124 PolarHBondContact O-N 2.79Å
121L97.6Very high96.7Very high0 Ų028.3 Ų28.30%015%0.151CC..Hα-helixtrans-60.8-45.1174.6-68.2-179000111.1I67 M74 A117 A118 Y119 C123 C124 G125 I126 L129 F144 W148 I172I67-L121 HydrophobicContact CD1-CD2 3.7Å; M74-L121 HydrophobicContact CG-CD1 4.36Å; M74-L121 HydrophobicContact CG-CD2 4.05Å; M74-L121 HydrophobicContact CG-CG 4.13Å; M74-L121 HydrophobicContact SD-CD1 3.9Å; M74-L121 HydrophobicContact SD-CD2 4.45Å; M74-L121 HydrophobicContact SD-CG 4.33Å; A117-L121 WeakPolarHBondContact O-CG 3.35Å; A117-L121 PolarHBondContact O-N 3.39Å; A118-L121 PolarHBondContact O-N 3.12Å; Y119-L121 PolarHBondContact O-N 3.19Å; L121-C123 VanDerWaalsContact C-N 3.34Å; L121-C123 PolarHBondContact O-N 2.83Å; L121-C124 CarbonylContact O-C 3.54Å; L121-C124 PolarHBondContact O-N 2.87Å; L121-G125 PolarHBondContact O-N 3.36Å; L121-G125 VanDerWaalsContact O-N 3.1Å; L121-I126 HydrophobicContact CB-CB 4.18Å; L121-I126 HydrophobicContact CD2-CB 4.14Å; L121-I126 HydrophobicContact CD2-CD1 3.9Å; L121-I126 HydrophobicContact CD2-CG2 4.01Å; L121-I126 PolarHBondContact O-N 3.31Å; L121-L129 HydrophobicContact CD2-CD1 4.47Å; L121-F144 HydrophobicContact CD1-CE1 3.79Å; L121-F144 HydrophobicContact CD1-CZ 4.14Å; L121-W148 HydrophobicContact CB-CH2 4.25Å; L121-W148 HydrophobicContact CD1-CH2 4.29Å; L121-W148 HydrophobicContact CD1-CZ3 4.14Å; L121-I172 HydrophobicContact CD1-CD1 3.98Å
122L96.1Very high96.8Very high0 Ų024.3 Ų24.30%013%0.125CC..Hα-helixtrans-62.2-40176.7-71.4166.3000111.6A118 Y119 N120 C124 G125 W148 L152 L155 I161 K165 H169A118-L122 WeakPolarHBondContact O-CB 3.26Å; A118-L122 WeakPolarHBondContact O-CD1 3.28Å; A118-L122 VanDerWaalsContact O-CG 3.27Å; A118-L122 WeakPolarHBondContact O-CG 3.27Å; A118-L122 PolarHBondContact O-N 3.1Å; Y119-L122 WeakPolarHBondContact O-CB 3.39Å; Y119-L122 PolarHBondContact O-N 2.87Å; N120-L122 VanDerWaalsContact C-N 3.34Å; N120-L122 PolarHBondContact O-N 3.17Å; L122-C124 PolarHBondContact O-N 3.23Å; L122-G125 WeakPolarHBondContact O-CA 3.5Å; L122-G125 PolarHBondContact O-N 3.28Å; L122-W148 HydrophobicContact CD2-CZ2 3.98Å; L122-W148 HydrophobicContact CG-CH2 4.3Å; L122-W148 HydrophobicContact CG-CZ2 4.14Å; L122-L152 HydrophobicContact CD1-CD2 3.6Å; L122-L152 HydrophobicContact CD2-CD2 4.33Å; L122-L155 HydrophobicContact CD1-CD1 3.98Å; L122-I161 HydrophobicContact CD1-CD1 3.94Å; L122-I161 HydrophobicContact CD1-CG2 4.25Å; L122-K165 WeakPolarHBondContact O-CE 3.46Å; L122-K165 PolarHBondContact O-NZ 2.97Å; L122-H169 HydrophobicContact CD2-CB 3.76Å
123C94.6Very high96.8Very high64 Ų6419.2 Ų19.243%0.43210%0.101SC..Hα-helixtrans-53.2-39.3175.1-75.40000112.4Y119 N120 L121Y119-C123 PolarHBondContact O-N 3.01Å; Y119-C123 PolarHBondContact O-SG 3.48Å; Y119-C123 VanDerWaalsContact O-SG 3.33Å; N120-C123 WeakPolarHBondContact O-CB 3.06Å; N120-C123 PolarHBondContact O-N 3.44Å; L121-C123 VanDerWaalsContact C-N 3.34Å; L121-C123 PolarHBondContact O-N 2.83Å
124C95.3Very high96.6Very high36 Ų3619.6 Ų19.624%0.24311%0.105CC..THydrogen-bonded Turntrans-85.4-3.7175.1-60.80000114.4Y65 I81 N120 L121 L122 I126Y65-C124 HydrophobicContact CD1-CB 4.46Å; Y65-C124 HydrophobicContact CE1-CB 4.26Å; I81-C124 HydrophobicContact CG2-CB 4.35Å; N120-C124 PolarHBondContact O-N 2.79Å; L121-C124 CarbonylContact O-C 3.54Å; L121-C124 PolarHBondContact O-N 2.87Å; L122-C124 PolarHBondContact O-N 3.23Å; C124-I126 VanDerWaalsContact C-N 3.3Å; C124-I126 HydrophobicContact CB-CD1 3.69Å; C124-I126 HydrophobicContact CB-CG1 3.83Å
125G95.1Very high96.1Very high16 Ų1619.4 Ų19.417%0.16511%0.106CC..THydrogen-bonded Turntrans73.618.9-175.200000113.8V33 L121 L122 N127V33-G125 WeakPolarHBondContact CB-O 3.34Å; L121-G125 PolarHBondContact O-N 3.36Å; L121-G125 VanDerWaalsContact O-N 3.1Å; L122-G125 WeakPolarHBondContact O-CA 3.5Å; L122-G125 PolarHBondContact O-N 3.28Å; G125-N127 PolarHBondContact O-N 2.94Å
126I96.7Very high95.7Very high0 Ų021.1 Ų21.10%013%0.125CC..  trans-79.5115.8-178.3-60.8164.8000109.5V33 Y65 I81 L121 C124 L129V33-I126 HydrophobicContact CG1-CG1 3.78Å; Y65-I126 HydrophobicContact CD2-CD1 4.28Å; Y65-I126 HydrophobicContact CD2-CG1 4.19Å; Y65-I126 HydrophobicContact CG-CD1 4.01Å; Y65-I126 HydrophobicContact CG-CG1 4.42Å; I81-I126 HydrophobicContact CG2-CD1 3.81Å; L121-I126 HydrophobicContact CB-CB 4.18Å; L121-I126 HydrophobicContact CD2-CB 4.14Å; L121-I126 HydrophobicContact CD2-CD1 3.9Å; L121-I126 HydrophobicContact CD2-CG2 4.01Å; L121-I126 PolarHBondContact O-N 3.31Å; C124-I126 VanDerWaalsContact C-N 3.3Å; C124-I126 HydrophobicContact CB-CD1 3.69Å; C124-I126 HydrophobicContact CB-CG1 3.83Å; I126-L129 HydrophobicContact CG2-CD1 4.48Å
127N94.2Very high95.5Very high30 Ų3016.3 Ų16.316%0.1611%0.106CC..  trans-128.53.9169.166.5-20.8000113.3G125 H169 I172 K173G125-N127 PolarHBondContact O-N 2.94Å; N127-H169 HydrophobicContact CB-CB 4.13Å; N127-I172 CarbonylContact O-C 3.59Å; N127-I172 WeakPolarHBondContact O-CA 3.42Å; N127-K173 PolarHBondContact O-N 3.44Å
128N96.6Very high95.3Very high1 Ų116.3 Ų16.31%0.00511%0.106CC..EExtended strand (participates in β ladder)trans-119.2124.4170.5-54.1-78.5000108.1V33 I34 G35 K173 L340 M341V33-N128 WeakPolarHBondContact O-CB 3.47Å; V33-N128 PolarHBondContact O-N 3.36Å; V33-N128 PolarHBondContact O-ND2 2.97Å; I34-N128 CarbonylContact C-O 3.58Å; I34-N128 WeakPolarHBondContact CA-O 3.36Å; I34-N128 HydrophobicContact CG1-CB 4.18Å; G35-N128 PolarHBondContact N-O 3.27Å; N128-K173 CarbonylContact C-O 3.59Å; N128-K173 WeakPolarHBondContact OD1-CD 3.07Å; N128-L340 HydrophobicContact CB-CD1 4.1Å; N128-L340 HydrophobicContact CB-CD2 4.17Å; N128-M341 HydrophobicContact CB-CE 4.41Å
129L97.2Very high94.9Very high0 Ų019.2 Ų19.20%012%0.124CC..EExtended strand (participates in β ladder)trans-126.4130.6-172.5-163.572.1000110.7G35 F37 I67 M74 L121 I126 I172 K173 I174 V175G35-L129 CarbonylContact O-C 3.41Å; G35-L129 WeakPolarHBondContact O-CA 3.47Å; F37-L129 HydrophobicContact CD1-CD1 4.01Å; F37-L129 HydrophobicContact CD1-CD2 4.29Å; F37-L129 HydrophobicContact CD1-CG 4.05Å; F37-L129 HydrophobicContact CE1-CD1 4.11Å; F37-L129 HydrophobicContact CE1-CD2 3.55Å; F37-L129 HydrophobicContact CE1-CG 3.7Å; F37-L129 HydrophobicContact CZ-CD2 4.32Å; I67-L129 HydrophobicContact CD1-CD1 3.75Å; M74-L129 HydrophobicContact CE-CD1 4.25Å; M74-L129 HydrophobicContact CE-CD2 4.11Å; L121-L129 HydrophobicContact CD2-CD1 4.47Å; I126-L129 HydrophobicContact CG2-CD1 4.48Å; L129-I172 HydrophobicContact CB-CD1 4.2Å; L129-I172 HydrophobicContact CB-CG1 4.46Å; L129-I172 HydrophobicContact CD2-CD1 4.3Å; L129-K173 PolarHBondContact N-O 3.32Å; L129-I174 HydrophobicContact CB-CG1 4.23Å; L129-I174 HydrophobicContact CD2-CD1 4.32Å; L129-I174 WeakPolarHBondContact O-CA 3.41Å; L129-V175 PolarHBondContact O-N 2.81Å
130V98.3Very high94.6Very high0 Ų015.9 Ų15.90%012%0.117CC..EExtended strand (participates in β ladder)trans-106.1117.2168.3-176.90000108.8I34 G35 V36 F37 V53 I132 V175 L177 A336 L340I34-V130 HydrophobicContact CG2-CG2 4.11Å; G35-V130 PolarHBondContact O-N 2.99Å; V36-V130 WeakPolarHBondContact CA-O 3.48Å; V36-V130 HydrophobicContact CB-CB 4.18Å; V36-V130 HydrophobicContact CG2-CB 4Å; V36-V130 HydrophobicContact CG2-CG1 4.21Å; F37-V130 VanDerWaalsContact CD1-O 3.32Å; F37-V130 WeakPolarHBondContact CD1-O 3.16Å; F37-V130 PolarHBondContact N-O 3.47Å; V53-V130 HydrophobicContact CG1-CB 4.34Å; V53-V130 HydrophobicContact CG1-CG2 3.94Å; V53-V130 HydrophobicContact CG2-CG1 3.96Å; V53-V130 HydrophobicContact CG2-CG2 4.41Å; V130-I132 HydrophobicContact CG1-CG1 4.18Å; V130-V175 WeakPolarHBondContact CA-O 3.47Å; V130-L177 HydrophobicContact CG1-CD1 4.15Å; V130-L177 HydrophobicContact CG1-CG 4.2Å; V130-A336 HydrophobicContact CG1-CB 4.24Å; V130-A336 HydrophobicContact CG2-CB 4.4Å; V130-L340 HydrophobicContact CG2-CD1 3.41Å; V130-L340 VanDerWaalsContact CG2-CD1 3.41Å
131C97.6Very high94.4Very high0 Ų015 Ų150%011%0.112CC..EExtended strand (participates in β ladder)trans-99.1121174.6-177.80000109.5F37 L138 A141 V175 G176 L177F37-C131 HydrophobicContact CD1-CB 4.43Å; F37-C131 HydrophobicContact CE1-CB 3.53Å; F37-C131 HydrophobicContact CE2-CB 4.49Å; F37-C131 HydrophobicContact CZ-CB 3.59Å; F37-C131 WeakPolarHBondContact CZ-SG 3.06Å; C131-L138 HydrophobicContact CB-CD2 4.05Å; C131-A141 HydrophobicContact CB-CB 4.24Å; C131-V175 PolarHBondContact N-O 3Å; C131-G176 CarbonylContact O-C 3.47Å; C131-G176 WeakPolarHBondContact O-CA 3.14Å; C131-L177 PolarHBondContact O-N 3.44Å
132I97.9Very high94Very high0 Ų016.1 Ų16.10%012%0.118CC..EExtended strand (participates in β ladder)trans-109.8112.3174.1-48-176.6000108.2V36 F37 T38 S39 M46 A49 L50 V130 L177V36-I132 HydrophobicContact CG2-CD1 3.9Å; V36-I132 HydrophobicContact CG2-CG1 4.25Å; F37-I132 PolarHBondContact O-N 3.25Å; T38-I132 CarbonylContact C-O 3.56Å; T38-I132 VanDerWaalsContact CA-O 3.25Å; T38-I132 WeakPolarHBondContact CA-O 3.48Å; T38-I132 HydrophobicContact CG2-CB 3.85Å; T38-I132 HydrophobicContact CG2-CD1 4.41Å; T38-I132 HydrophobicContact CG2-CG2 4.13Å; S39-I132 PolarHBondContact N-O 2.95Å; M46-I132 HydrophobicContact CB-CG2 4.47Å; M46-I132 HydrophobicContact CG-CG2 3.97Å; A49-I132 HydrophobicContact CB-CD1 3.91Å; L50-I132 HydrophobicContact CB-CD1 4.43Å; V130-I132 HydrophobicContact CG1-CG1 4.18Å; I132-L177 WeakPolarHBondContact CA-O 3.41Å; I132-L177 HydrophobicContact CB-CB 4.45Å; I132-L177 HydrophobicContact CD1-CD1 4.16Å; I132-L177 HydrophobicContact CG1-CB 4.2Å; I132-L177 HydrophobicContact CG1-CD1 4.03Å; I132-L177 HydrophobicContact CG1-CG 4.42Å; I132-L177 HydrophobicContact CG2-CB 4.28Å
133G95.5Very high93.8Very high0 Ų019.6 Ų19.60%014%0.136CC..EExtended strand (participates in β ladder)trans176.6-172.4-176.500000114.8S39 L177 V178 G179S39-G133 WeakPolarHBondContact O-CA 3.39Å; G133-L177 PolarHBondContact N-O 3.01Å; G133-V178 CarbonylContact O-C 3.55Å; G133-V178 VanDerWaalsContact O-CA 3.3Å; G133-V178 WeakPolarHBondContact O-CA 3.42Å; G133-G179 CarbonylContact C-O 3.54Å; G133-G179 PolarHBondContact O-N 3.39Å
134G92.6Very high93.8Very high12 Ų1216.6 Ų16.612%0.12412%0.116CC..  trans-78.7-174.5177.700000114G136 S137 L138 G179G134-G136 VanDerWaalsContact C-N 3.34Å; G134-G136 PolarHBondContact O-N 3.26Å; G134-S137 PolarHBondContact O-N 3.39Å; G134-L138 WeakPolarHBondContact O-CG 3.48Å; G134-L138 PolarHBondContact O-N 3.45Å; G134-L138 VanDerWaalsContact O-N 3.16Å; G134-G179 PolarHBondContact N-O 3.34Å
135D87.7Confident93.7Very high20 Ų2017.5 Ų17.511%0.10711%0.114CC..Hα-helixtrans-53.4-45.8179.270.5-43.2000113.3S137 L138 T139 F185 R226 K375D135-S137 PolarHBondContact O-N 3.22Å; D135-L138 PolarHBondContact O-N 2.98Å; D135-T139 WeakPolarHBondContact O-CB 3.3Å; D135-T139 PolarHBondContact O-N 3.49Å; D135-T139 PolarHBondContact O-OG1 3.18Å; D135-F185 HydrophobicContact CB-CD2 3.97Å; D135-F185 HydrophobicContact CB-CE2 4.44Å; D135-R226 IonicContact OD1-NH1 3.3Å; D135-R226 PolarHBondContact OD1-NH1 2.83Å; D135-K375 IonicContact OD2-NZ 3.98Å; D135-K375 PolarHBondContact OD2-NZ 3.27Å
136G88.9Confident93.4Very high45 Ų4522.4 Ų22.446%0.46413%0.133SC..Hα-helixtrans-62.8-42178.700000112.9G134 L138 T139 G140G134-G136 VanDerWaalsContact C-N 3.34Å; G134-G136 PolarHBondContact O-N 3.26Å; G136-L138 PolarHBondContact O-N 3.2Å; G136-T139 PolarHBondContact O-N 3.37Å; G136-G140 PolarHBondContact O-N 2.87Å
137S93.6Very high93.4Very high10 Ų1024.6 Ų24.67%0.0714%0.143CC..Hα-helixtrans-63.7-43.6179.7-54.10000111.5S39 Y71 G134 D135 G140 A141S39-S137 PolarHBondContact O-OG 3.09Å; S39-S137 PolarHBondContact OG-OG 2.89Å; Y71-S137 PolarHBondContact OH-O 2.91Å; G134-S137 PolarHBondContact O-N 3.39Å; D135-S137 PolarHBondContact O-N 3.22Å; S137-G140 PolarHBondContact O-N 2.96Å; S137-A141 PolarHBondContact O-N 2.94Å
138L92Very high93.4Very high0 Ų023.2 Ų23.20%014%0.135CC..Hα-helixtrans-69.5-35.9178.5-64.8178.5000112.3C131 G134 D135 G136 A141 N142 G176 V178 F185 V351 L364C131-L138 HydrophobicContact CB-CD2 4.05Å; G134-L138 WeakPolarHBondContact O-CG 3.48Å; G134-L138 PolarHBondContact O-N 3.45Å; G134-L138 VanDerWaalsContact O-N 3.16Å; D135-L138 PolarHBondContact O-N 2.98Å; G136-L138 PolarHBondContact O-N 3.2Å; L138-A141 PolarHBondContact O-N 3.34Å; L138-N142 PolarHBondContact O-N 3.43Å; L138-G176 VanDerWaalsContact CD2-CA 3.41Å; L138-V178 HydrophobicContact CD1-CG2 3.85Å; L138-F185 HydrophobicContact CD1-CD2 4.49Å; L138-F185 HydrophobicContact CD1-CE2 3.85Å; L138-F185 HydrophobicContact CD1-CZ 3.86Å; L138-V351 HydrophobicContact CD1-CG2 4.21Å; L138-L364 HydrophobicContact CB-CD1 3.84Å
139T89.4Confident93.2Very high61 Ų6125.8 Ų25.837%0.37415%0.152SC..Hα-helixtrans-62.3-46.3173-560000110.9D135 G136 A141 N142 L143 V368D135-T139 WeakPolarHBondContact O-CB 3.3Å; D135-T139 PolarHBondContact O-N 3.49Å; D135-T139 PolarHBondContact O-OG1 3.18Å; G136-T139 PolarHBondContact O-N 3.37Å; T139-A141 VanDerWaalsContact C-N 3.3Å; T139-A141 PolarHBondContact O-N 2.84Å; T139-N142 PolarHBondContact O-N 2.73Å; T139-L143 PolarHBondContact O-N 2.72Å; T139-L143 VanDerWaalsContact O-N 3.09Å; T139-V368 HydrophobicContact CG2-CG1 4.45Å
140G92.3Very high93.1Very high20 Ų2029 Ų2921%0.20617%0.174CC..Hα-helixtrans-60-38.817500000112.8G136 S137 L143 F144G136-G140 PolarHBondContact O-N 2.87Å; S137-G140 PolarHBondContact O-N 2.96Å; G140-L143 PolarHBondContact O-N 3.26Å; G140-F144 WeakPolarHBondContact O-CB 3.21Å; G140-F144 PolarHBondContact O-N 2.88Å
141A93.2Very high93Very high0 Ų029.4 Ų29.40%018%0.177CC..Hα-helixtrans-65.1-42.2177.700000111.3Y71 C131 S137 L138 T139 F144 R145 I174Y71-A141 WeakPolarHBondContact OH-CA 3.39Å; Y71-A141 WeakPolarHBondContact OH-CB 3.28Å; Y71-A141 PolarHBondContact OH-N 2.94Å; C131-A141 HydrophobicContact CB-CB 4.24Å; S137-A141 PolarHBondContact O-N 2.94Å; L138-A141 PolarHBondContact O-N 3.34Å; T139-A141 VanDerWaalsContact C-N 3.3Å; T139-A141 PolarHBondContact O-N 2.84Å; A141-F144 PolarHBondContact O-N 2.98Å; A141-R145 PolarHBondContact O-N 3.4Å; A141-I174 HydrophobicContact CB-CD1 4.18Å; A141-I174 HydrophobicContact CB-CG2 4.04Å; A141-I174 WeakPolarHBondContact O-CD1 3.47Å
142N89.8Confident92.9Very high24 Ų2429.6 Ų29.613%0.12818%0.178CC..Hα-helixtrans-62-46176.7-17146.7000112.2L138 T139 F144 R145 Q146 L364L138-N142 PolarHBondContact O-N 3.43Å; T139-N142 PolarHBondContact O-N 2.73Å; N142-F144 VanDerWaalsContact C-N 3.34Å; N142-F144 PolarHBondContact O-N 3.26Å; N142-R145 WeakPolarHBondContact O-CB 3.45Å; N142-R145 PolarHBondContact O-N 3.29Å; N142-Q146 PolarHBondContact ND2-NE2 3.19Å; N142-Q146 WeakPolarHBondContact O-CG 3.18Å; N142-Q146 PolarHBondContact O-N 3.01Å; N142-Q146 VanDerWaalsContact O-N 3.11Å; N142-L364 HydrophobicContact CB-CD2 3.71Å; N142-L364 HydrophobicContact CB-CG 4.37Å
143L91.7Very high92.7Very high73 Ų7337.1 Ų37.138%0.38221%0.21SC..Hα-helixtrans-59.1-47.5176.4178.664.4000110.8T139 G140 R145 Q146 E147T139-L143 PolarHBondContact O-N 2.72Å; T139-L143 VanDerWaalsContact O-N 3.09Å; G140-L143 PolarHBondContact O-N 3.26Å; L143-R145 PolarHBondContact O-N 2.93Å; L143-Q146 WeakPolarHBondContact O-CB 3.36Å; L143-Q146 PolarHBondContact O-N 2.84Å; L143-E147 HydrophobicContact CD1-CG 4.25Å; L143-E147 PolarHBondContact O-N 3.34Å
144F94.8Very high92.8Very high0 Ų041 Ų410%023%0.228CC..Hα-helixtrans-57.2-37.1178.7-173.6-115000112.8M74 F108 R114 A117 A118 L121 G140 A141 N142 W148 M151 I172M74-F144 HydrophobicContact SD-CE1 4.37Å; M74-F144 HydrophobicContact SD-CZ 4.49Å; F108-F144 HydrophobicContact CE1-CB 4.42Å; F108-F144 HydrophobicContact CE1-CD2 4.4Å; F108-F144 HydrophobicContact CE2-CD2 4Å; F108-F144 HydrophobicContact CE2-CE2 4.01Å; F108-F144 HydrophobicContact CZ-CB 4.04Å; F108-F144 HydrophobicContact CZ-CD1 4.41Å; F108-F144 AromaticContact CZ-CD2 3.48Å; F108-F144 HydrophobicContact CZ-CD2 3.48Å; F108-F144 VanDerWaalsContact CZ-CD2 3.48Å; F108-F144 AromaticContact CZ-CE2 3.95Å; F108-F144 HydrophobicContact CZ-CE2 3.95Å; F108-F144 AromaticContact CZ-CG 3.74Å; F108-F144 HydrophobicContact CZ-CG 3.74Å; R114-F144 HydrophobicContact CB-CD2 4.05Å; R114-F144 HydrophobicContact CB-CE2 4.05Å; R114-F144 HydrophobicContact CG-CD2 4.25Å; R114-F144 WeakPolarHBondContact O-CE2 3.39Å; A117-F144 HydrophobicContact CB-CE2 4.21Å; A117-F144 HydrophobicContact CB-CZ 4.17Å; A118-F144 HydrophobicContact CB-CE2 4.33Å; A118-F144 HydrophobicContact CB-CZ 4.03Å; L121-F144 HydrophobicContact CD1-CE1 3.79Å; L121-F144 HydrophobicContact CD1-CZ 4.14Å; G140-F144 WeakPolarHBondContact O-CB 3.21Å; G140-F144 PolarHBondContact O-N 2.88Å; A141-F144 PolarHBondContact O-N 2.98Å; N142-F144 VanDerWaalsContact C-N 3.34Å; N142-F144 PolarHBondContact O-N 3.26Å; F144-W148 HydrophobicContact CD1-CE3 4.45Å; F144-W148 AromaticContact CE1-CE3 3.84Å; F144-W148 HydrophobicContact CE1-CE3 3.84Å; F144-W148 AromaticContact CE1-CZ3 3.58Å; F144-W148 HydrophobicContact CE1-CZ3 3.58Å; F144-W148 HydrophobicContact CZ-CE3 4Å; F144-W148 AromaticContact CZ-CZ3 3.65Å; F144-W148 HydrophobicContact CZ-CZ3 3.65Å; F144-W148 PolarHBondContact O-N 2.96Å; F144-M151 HydrophobicContact CD2-CE 3.64Å; F144-M151 HydrophobicContact CD2-SD 4.26Å; F144-M151 HydrophobicContact CE2-CE 3.49Å; F144-M151 VanDerWaalsContact CE2-CE 3.49Å; F144-M151 HydrophobicContact CE2-SD 3.87Å; F144-M151 HydrophobicContact CG-CE 4.38Å; F144-M151 HydrophobicContact CZ-CE 4.13Å; F144-M151 WeakPolarHBondContact O-CE 3.35Å; F144-I172 HydrophobicContact CD1-CD1 4.48Å; F144-I172 HydrophobicContact CE1-CD1 4.08Å
145R92Very high92.9Very high55 Ų5540.7 Ų40.721%0.20822%0.224CC..Hα-helixtrans-66.3-44.9173.4-170.1-169.893.3114.5-2.7112.8A141 N142 L143 E147 W148 I172 I174 A347 P349A141-R145 PolarHBondContact O-N 3.4Å; N142-R145 WeakPolarHBondContact O-CB 3.45Å; N142-R145 PolarHBondContact O-N 3.29Å; L143-R145 PolarHBondContact O-N 2.93Å; R145-E147 VanDerWaalsContact C-N 3.25Å; R145-E147 PolarHBondContact O-N 3.06Å; R145-W148 WeakPolarHBondContact O-CB 3.24Å; R145-W148 PolarHBondContact O-N 3.02Å; R145-W148 VanDerWaalsContact O-N 3.12Å; R145-I172 HydrophobicContact CB-CG2 4.09Å; R145-I172 HydrophobicContact CG-CG2 3.8Å; R145-I172 WeakPolarHBondContact CG-O 3.22Å; R145-I174 HydrophobicContact CB-CD1 3.81Å; R145-I174 HydrophobicContact CB-CG1 4.41Å; R145-A347 PolarHBondContact NH1-O 3.42Å; R145-P349 VanDerWaalsContact NE-CG 3.33Å
146Q90.6Very high93.2Very high119 Ų11943.1 Ų43.156%0.55624%0.237SC*.Hα-helixtrans-62.6-37.6-178.6-69.8174-1.300111.1N142 L143 W148 P149N142-Q146 PolarHBondContact ND2-NE2 3.19Å; N142-Q146 WeakPolarHBondContact O-CG 3.18Å; N142-Q146 PolarHBondContact O-N 3.01Å; N142-Q146 VanDerWaalsContact O-N 3.11Å; L143-Q146 WeakPolarHBondContact O-CB 3.36Å; L143-Q146 PolarHBondContact O-N 2.84Å; Q146-W148 VanDerWaalsContact C-N 3.3Å; Q146-W148 PolarHBondContact O-N 2.97Å; Q146-P149 WeakPolarHBondContact O-CD 3.34Å
147E94.7Very high93.5Very high46 Ų4649.1 Ų49.122%0.21525%0.252CS..THydrogen-bonded Turntrans-79.6-8.1176.8-65.3-178.317700113.6R114 L143 R145 S150 M151R114-E147 IonicContact CZ-OE1 3.33Å; R114-E147 IonicContact CZ-OE2 2.71Å; R114-E147 IonicContact NE-OE1 3.09Å; R114-E147 IonicContact NE-OE2 3.61Å; R114-E147 PolarHBondContact NE-OE2 2.91Å; R114-E147 IonicContact NH2-OE1 3.32Å; R114-E147 PolarHBondContact NH2-OE1 3.39Å; R114-E147 IonicContact NH2-OE2 3.82Å; R114-E147 PolarHBondContact NH2-OE2 3.08Å; L143-E147 HydrophobicContact CD1-CG 4.25Å; L143-E147 PolarHBondContact O-N 3.34Å; R145-E147 VanDerWaalsContact C-N 3.25Å; R145-E147 PolarHBondContact O-N 3.06Å; E147-S150 PolarHBondContact O-N 3.34Å; E147-S150 VanDerWaalsContact O-N 3.17Å; E147-S150 PolarHBondContact O-OG 3.31Å; E147-M151 HydrophobicContact CB-CE 4.06Å; E147-M151 WeakPolarHBondContact O-CG 3.43Å; E147-M151 PolarHBondContact O-N 3.47Å
148W94.8Very high93.6Very high1 Ų154.6 Ų54.60%0.00427%0.271CS..Hα-helixtrans-55-48.7-175.5-170.5-93.4000113.3A118 L121 L122 F144 R145 Q146 S150 M151 L152 H169 I172A118-W148 HydrophobicContact CB-CE3 4.2Å; A118-W148 HydrophobicContact CB-CH2 4.21Å; A118-W148 HydrophobicContact CB-CZ3 3.7Å; L121-W148 HydrophobicContact CB-CH2 4.25Å; L121-W148 HydrophobicContact CD1-CH2 4.29Å; L121-W148 HydrophobicContact CD1-CZ3 4.14Å; L122-W148 HydrophobicContact CD2-CZ2 3.98Å; L122-W148 HydrophobicContact CG-CH2 4.3Å; L122-W148 HydrophobicContact CG-CZ2 4.14Å; F144-W148 HydrophobicContact CD1-CE3 4.45Å; F144-W148 AromaticContact CE1-CE3 3.84Å; F144-W148 HydrophobicContact CE1-CE3 3.84Å; F144-W148 AromaticContact CE1-CZ3 3.58Å; F144-W148 HydrophobicContact CE1-CZ3 3.58Å; F144-W148 HydrophobicContact CZ-CE3 4Å; F144-W148 AromaticContact CZ-CZ3 3.65Å; F144-W148 HydrophobicContact CZ-CZ3 3.65Å; F144-W148 PolarHBondContact O-N 2.96Å; R145-W148 WeakPolarHBondContact O-CB 3.24Å; R145-W148 PolarHBondContact O-N 3.02Å; R145-W148 VanDerWaalsContact O-N 3.12Å; Q146-W148 VanDerWaalsContact C-N 3.3Å; Q146-W148 PolarHBondContact O-N 2.97Å; W148-S150 VanDerWaalsContact C-N 3.32Å; W148-S150 PolarHBondContact O-N 3.15Å; W148-M151 HydrophobicContact CB-CE 4.43Å; W148-M151 HydrophobicContact CE3-CE 4.02Å; W148-M151 PolarHBondContact O-N 3.03Å; W148-L152 WeakPolarHBondContact O-CG 3.4Å; W148-L152 PolarHBondContact O-N 3.05Å; W148-H169 PolarHBondContact NE1-O 2.9Å; W148-I172 HydrophobicContact CB-CG2 3.86Å; W148-I172 HydrophobicContact CD2-CB 3.66Å; W148-I172 HydrophobicContact CD2-CG2 3.59Å; W148-I172 HydrophobicContact CE3-CB 3.93Å; W148-I172 HydrophobicContact CE3-CD1 3.97Å; W148-I172 HydrophobicContact CE3-CG2 3.71Å; W148-I172 HydrophobicContact CG-CB 4.03Å; W148-I172 HydrophobicContact CG-CG2 3.68Å; W148-I172 HydrophobicContact CH2-CB 4.44Å; W148-I172 HydrophobicContact CH2-CD1 3.92Å; W148-I172 HydrophobicContact CZ2-CB 4.21Å; W148-I172 HydrophobicContact CZ2-CD1 4.47Å; W148-I172 HydrophobicContact CZ3-CB 4.32Å; W148-I172 HydrophobicContact CZ3-CD1 3.64Å; W148-I172 HydrophobicContact CZ3-CG2 4.46Å
149P93.2Very high93.6Very high56 Ų5657.5 Ų57.536%0.36430%0.302SS..Hα-helixtrans-63.8-34.8179.9-21.735.3000113.3Q146 K153Q146-P149 WeakPolarHBondContact O-CD 3.34Å; P149-K153 WeakPolarHBondContact O-CG 3.42Å; P149-K153 PolarHBondContact O-N 3.04Å
150S94.9Very high93.7Very high66 Ų6657.2 Ų57.246%0.46230%0.302SS..Hα-helixtrans-69.6-42175.243.30000111.6E147 W148 L152 K153 E154E147-S150 PolarHBondContact O-N 3.34Å; E147-S150 VanDerWaalsContact O-N 3.17Å; E147-S150 PolarHBondContact O-OG 3.31Å; W148-S150 VanDerWaalsContact C-N 3.32Å; W148-S150 PolarHBondContact O-N 3.15Å; S150-L152 VanDerWaalsContact C-N 3.32Å; S150-L152 PolarHBondContact O-N 3.48Å; S150-K153 PolarHBondContact O-N 2.75Å; S150-E154 PolarHBondContact O-N 3.3Å
151M96.5Very high93.8Very high9 Ų957 Ų574%0.04430%0.296CS..Hα-helixtrans-62.1-38.7176.6-71.5-173.8-66.600112R114 L115 A118 F144 E147 W148 E154 L155R114-M151 VanDerWaalsContact C-SD 3.53Å; R114-M151 HydrophobicContact CB-SD 3.84Å; L115-M151 HydrophobicContact CD1-CB 3.88Å; L115-M151 HydrophobicContact CD1-CG 4.03Å; A118-M151 HydrophobicContact CB-CB 4.31Å; A118-M151 HydrophobicContact CB-CE 4.15Å; A118-M151 HydrophobicContact CB-SD 3.98Å; F144-M151 HydrophobicContact CD2-CE 3.64Å; F144-M151 HydrophobicContact CD2-SD 4.26Å; F144-M151 HydrophobicContact CE2-CE 3.49Å; F144-M151 VanDerWaalsContact CE2-CE 3.49Å; F144-M151 HydrophobicContact CE2-SD 3.87Å; F144-M151 HydrophobicContact CG-CE 4.38Å; F144-M151 HydrophobicContact CZ-CE 4.13Å; F144-M151 WeakPolarHBondContact O-CE 3.35Å; E147-M151 HydrophobicContact CB-CE 4.06Å; E147-M151 WeakPolarHBondContact O-CG 3.43Å; E147-M151 PolarHBondContact O-N 3.47Å; W148-M151 HydrophobicContact CB-CE 4.43Å; W148-M151 HydrophobicContact CE3-CE 4.02Å; W148-M151 PolarHBondContact O-N 3.03Å; M151-E154 PolarHBondContact O-N 3.42Å; M151-L155 WeakPolarHBondContact O-CB 3.48Å; M151-L155 VanDerWaalsContact O-CG 3.31Å; M151-L155 WeakPolarHBondContact O-CG 3.48Å; M151-L155 PolarHBondContact O-N 2.9Å
152L95.1Very high93.8Very high5 Ų561 Ų613%0.02632%0.32CS..Hα-helixtrans-62.3-43.8175.3-69.2-179000112.6L122 W148 S150 E154 L155 L156 I161 V166 H169L122-L152 HydrophobicContact CD1-CD2 3.6Å; L122-L152 HydrophobicContact CD2-CD2 4.33Å; W148-L152 WeakPolarHBondContact O-CG 3.4Å; W148-L152 PolarHBondContact O-N 3.05Å; S150-L152 VanDerWaalsContact C-N 3.32Å; S150-L152 PolarHBondContact O-N 3.48Å; L152-E154 VanDerWaalsContact C-N 3.29Å; L152-E154 PolarHBondContact O-N 3.13Å; L152-L155 PolarHBondContact O-N 3.01Å; L152-L156 WeakPolarHBondContact O-CB 3.5Å; L152-L156 PolarHBondContact O-N 2.66Å; L152-I161 HydrophobicContact CD2-CD1 4.08Å; L152-V166 HydrophobicContact CB-CG1 4.36Å; L152-V166 HydrophobicContact CD1-CG1 4.27Å; L152-H169 VanDerWaalsContact CD1-O 3.3Å; L152-H169 WeakPolarHBondContact CD1-O 3.37Å
153K94.6Very high93.9Very high157 Ų15763 Ų6368%0.68334%0.341SS*.Hα-helixtrans-60.7-43177.4-71.8174.9-177.9-1790110.9P149 S150 L156 H157P149-K153 WeakPolarHBondContact O-CG 3.42Å; P149-K153 PolarHBondContact O-N 3.04Å; S150-K153 PolarHBondContact O-N 2.75Å; K153-L156 PolarHBondContact O-N 3.12Å; K153-H157 WeakPolarHBondContact O-CB 3.42Å; K153-H157 PolarHBondContact O-N 3.17Å
154E95.7Very high93.9Very high81 Ų8167 Ų6738%0.37936%0.357SS..Hα-helixtrans-69.1-44.4180-177.2161.1-172.500112.6L115 S150 M151 L152 L156 H157 R158L115-E154 HydrophobicContact CD1-CB 4.03Å; L115-E154 HydrophobicContact CD1-CG 4.08Å; L115-E154 HydrophobicContact CD2-CG 4.03Å; S150-E154 PolarHBondContact O-N 3.3Å; M151-E154 PolarHBondContact O-N 3.42Å; L152-E154 VanDerWaalsContact C-N 3.29Å; L152-E154 PolarHBondContact O-N 3.13Å; E154-L156 VanDerWaalsContact C-N 3.28Å; E154-L156 PolarHBondContact O-N 2.97Å; E154-H157 PolarHBondContact O-N 3.37Å; E154-R158 HydrophobicContact CG-CG 4.47Å; E154-R158 WeakPolarHBondContact O-CB 3.31Å; E154-R158 WeakPolarHBondContact O-CG 3.43Å; E154-R158 PolarHBondContact O-N 3.22Å; E154-R158 IonicContact OE1-CZ 2.71Å; E154-R158 VanDerWaalsContact OE1-CZ 3.3Å; E154-R158 IonicContact OE1-NE 3.43Å; E154-R158 PolarHBondContact OE1-NE 3.34Å; E154-R158 IonicContact OE1-NH2 2.69Å; E154-R158 PolarHBondContact OE1-NH2 3.24Å
155L95.8Very high93.7Very high6 Ų669.9 Ų69.93%0.03137%0.37CS..Hα-helixtrans-61.4-37.3175.2-73.4172.3000112.4L115 A118 Y119 L122 M151 L152 G159 S160 I161L115-L155 HydrophobicContact CD1-CD1 4.41Å; L115-L155 HydrophobicContact CD1-CD2 4.01Å; L115-L155 HydrophobicContact CD1-CG 3.71Å; L115-L155 HydrophobicContact CD2-CD2 4.4Å; L115-L155 HydrophobicContact CG-CD2 3.85Å; L115-L155 HydrophobicContact CG-CG 4.13Å; A118-L155 HydrophobicContact CB-CD1 4.23Å; Y119-L155 HydrophobicContact CD2-CD2 4.41Å; L122-L155 HydrophobicContact CD1-CD1 3.98Å; M151-L155 WeakPolarHBondContact O-CB 3.48Å; M151-L155 VanDerWaalsContact O-CG 3.31Å; M151-L155 WeakPolarHBondContact O-CG 3.48Å; M151-L155 PolarHBondContact O-N 2.9Å; L152-L155 PolarHBondContact O-N 3.01Å; L155-G159 PolarHBondContact O-N 3.29Å; L155-S160 PolarHBondContact O-N 3.41Å; L155-I161 HydrophobicContact CB-CD1 3.55Å; L155-I161 HydrophobicContact CB-CG1 3.75Å; L155-I161 HydrophobicContact CB-CG2 4.4Å; L155-I161 HydrophobicContact CD1-CD1 4.25Å
156L94.9Very high93.7Very high71 Ų7168.8 Ų68.837%0.37237%0.369SS..Hα-helixtrans-67.1-44.8174.9-177.466.4000111L152 K153 E154 R158 G159 I161 A163 V166L152-L156 WeakPolarHBondContact O-CB 3.5Å; L152-L156 PolarHBondContact O-N 2.66Å; K153-L156 PolarHBondContact O-N 3.12Å; E154-L156 VanDerWaalsContact C-N 3.28Å; E154-L156 PolarHBondContact O-N 2.97Å; L156-R158 VanDerWaalsContact C-N 3.32Å; L156-R158 PolarHBondContact O-N 2.94Å; L156-G159 PolarHBondContact O-N 3.07Å; L156-I161 HydrophobicContact CB-CG1 4.41Å; L156-I161 WeakPolarHBondContact CD1-O 3.31Å; L156-A163 HydrophobicContact CD1-CB 4.33Å; L156-V166 HydrophobicContact CB-CG2 4.29Å; L156-V166 HydrophobicContact CD1-CG2 4.41Å; L156-V166 HydrophobicContact CD2-CG2 4.47Å
157H94.5Very high93.7Very high172 Ų17266.8 Ų66.880%0.79637%0.373SS*.Hα-helixtrans-62.2-39.2177.7-17667.4000112.2K153 E154 G159K153-H157 WeakPolarHBondContact O-CB 3.42Å; K153-H157 PolarHBondContact O-N 3.17Å; E154-H157 PolarHBondContact O-N 3.37Å; H157-G159 PolarHBondContact O-N 2.89Å
158R94.8Very high93.4Very high124 Ų12471.8 Ų71.847%0.46839%0.394SS..THydrogen-bonded Turntrans-72.6-2.5174.2-66.6-179.6-175.2-1468113.4E112 E154 L156 S160E112-R158 IonicContact OE1-NH2 3.81Å; E112-R158 PolarHBondContact OE1-NH2 3.35Å; E154-R158 HydrophobicContact CG-CG 4.47Å; E154-R158 WeakPolarHBondContact O-CB 3.31Å; E154-R158 WeakPolarHBondContact O-CG 3.43Å; E154-R158 PolarHBondContact O-N 3.22Å; E154-R158 IonicContact OE1-CZ 2.71Å; E154-R158 VanDerWaalsContact OE1-CZ 3.3Å; E154-R158 IonicContact OE1-NE 3.43Å; E154-R158 PolarHBondContact OE1-NE 3.34Å; E154-R158 IonicContact OE1-NH2 2.69Å; E154-R158 PolarHBondContact OE1-NH2 3.24Å; L156-R158 VanDerWaalsContact C-N 3.32Å; L156-R158 PolarHBondContact O-N 2.94Å; R158-S160 PolarHBondContact O-N 2.79Å
159G92.5Very high93.2Very high62 Ų6272.2 Ų72.264%0.63940%0.396SS*.THydrogen-bonded Turntrans6813.8-177.800000114.6L155 L156 H157L155-G159 PolarHBondContact O-N 3.29Å; L156-G159 PolarHBondContact O-N 3.07Å; H157-G159 PolarHBondContact O-N 2.89Å
160S92.1Very high93.1Very high55 Ų5572.7 Ų72.739%0.38540%0.399SS..SBendtrans-77.7-23.2-177.6-54.30000112.6Y119 L155 R158Y119-S160 WeakPolarHBondContact CE2-O 3.29Å; L155-S160 PolarHBondContact O-N 3.41Å; R158-S160 PolarHBondContact O-N 2.79Å
161I93.5Very high92.9Very high14 Ų1471.7 Ų71.77%0.07239%0.389CS..SBendtrans-135.7158177.864.7178.9000110.9Y119 L122 L152 L155 L156 V166Y119-I161 HydrophobicContact CD2-CG2 4.03Å; Y119-I161 HydrophobicContact CE2-CG2 4.37Å; L122-I161 HydrophobicContact CD1-CD1 3.94Å; L122-I161 HydrophobicContact CD1-CG2 4.25Å; L152-I161 HydrophobicContact CD2-CD1 4.08Å; L155-I161 HydrophobicContact CB-CD1 3.55Å; L155-I161 HydrophobicContact CB-CG1 3.75Å; L155-I161 HydrophobicContact CB-CG2 4.4Å; L155-I161 HydrophobicContact CD1-CD1 4.25Å; L156-I161 HydrophobicContact CB-CG1 4.41Å; L156-I161 WeakPolarHBondContact CD1-O 3.31Å; I161-V166 HydrophobicContact CD1-CG2 3.5Å; I161-V166 VanDerWaalsContact CD1-CG2 3.5Å; I161-V166 HydrophobicContact CG1-CG2 4.03Å
162T93Very high92.7Very high84 Ų8471.3 Ų71.352%0.51539%0.387SS..  trans-87.9156.717863.70000112.1E164 K165 V166T162-E164 PolarHBondContact O-N 2.84Å; T162-K165 WeakPolarHBondContact O-CB 3.45Å; T162-K165 PolarHBondContact O-N 2.89Å; T162-K165 WeakPolarHBondContact OG1-CB 3.34Å; T162-K165 PolarHBondContact OG1-N 2.93Å; T162-V166 PolarHBondContact O-N 2.8Å; T162-V166 VanDerWaalsContact O-N 3.14Å
163A91.6Very high92.7Very high67 Ų6773.1 Ų73.155%0.55440%0.395SS*.Hα-helixtrans-59.1-35.2174.400000112.6L156 K165 V166 A167L156-A163 HydrophobicContact CD1-CB 4.33Å; A163-K165 VanDerWaalsContact C-N 3.31Å; A163-K165 PolarHBondContact O-N 2.71Å; A163-V166 PolarHBondContact O-N 3.23Å; A163-A167 WeakPolarHBondContact O-CB 3.44Å; A163-A167 PolarHBondContact O-N 3.03Å
164E92.7Very high92.7Very high156 Ų15666 Ų6673%0.72936%0.364SS*.Hα-helixtrans-60.6-41.1173.9-172-174.3172.500111.6T162 A167 K168T162-E164 PolarHBondContact O-N 2.84Å; E164-A167 PolarHBondContact O-N 3.5Å; E164-K168 WeakPolarHBondContact O-CB 3.38Å; E164-K168 PolarHBondContact O-N 3.48Å
165K91.1Very high92.7Very high61 Ų6162.2 Ų62.227%0.26535%0.346SS..Hα-helixtrans-69.2-35.4-179.9-159.4152.9-169.41770112.2L122 T162 A163 H169L122-K165 WeakPolarHBondContact O-CE 3.46Å; L122-K165 PolarHBondContact O-NZ 2.97Å; T162-K165 WeakPolarHBondContact O-CB 3.45Å; T162-K165 PolarHBondContact O-N 2.89Å; T162-K165 WeakPolarHBondContact OG1-CB 3.34Å; T162-K165 PolarHBondContact OG1-N 2.93Å; A163-K165 VanDerWaalsContact C-N 3.31Å; A163-K165 PolarHBondContact O-N 2.71Å; K165-H169 PolarHBondContact O-N 3.01Å; K165-H169 PolarHBondContact O-ND1 3.34Å
166V90.4Very high92.8Very high32 Ų3262 Ų6219%0.19435%0.345CS..Hα-helixtrans-63.6-48.2170.6175.40000110.4L152 L156 I161 T162 A163 K168 H169L152-V166 HydrophobicContact CB-CG1 4.36Å; L152-V166 HydrophobicContact CD1-CG1 4.27Å; L156-V166 HydrophobicContact CB-CG2 4.29Å; L156-V166 HydrophobicContact CD1-CG2 4.41Å; L156-V166 HydrophobicContact CD2-CG2 4.47Å; I161-V166 HydrophobicContact CD1-CG2 3.5Å; I161-V166 VanDerWaalsContact CD1-CG2 3.5Å; I161-V166 HydrophobicContact CG1-CG2 4.03Å; T162-V166 PolarHBondContact O-N 2.8Å; T162-V166 VanDerWaalsContact O-N 3.14Å; A163-V166 PolarHBondContact O-N 3.23Å; V166-K168 VanDerWaalsContact C-N 3.27Å; V166-K168 PolarHBondContact O-N 3.24Å; V166-H169 CarbonylContact O-C 3.22Å; V166-H169 VanDerWaalsContact O-C 3.31Å; V166-H169 PolarHBondContact O-N 3.46Å; V166-H169 VanDerWaalsContact O-N 3.15Å
167A91Very high92.9Very high77 Ų7758.6 Ų58.664%0.63633%0.327SS*.Hα-helixtrans-62.5-33.3-179.600000112.9A163 E164 P170A163-A167 WeakPolarHBondContact O-CB 3.44Å; A163-A167 PolarHBondContact O-N 3.03Å; E164-A167 PolarHBondContact O-N 3.5Å; A167-P170 WeakPolarHBondContact O-CD 3.43Å
168K89.3Confident93Very high151 Ų15150.5 Ų50.566%0.65729%0.29SS*.Hα-helixtrans-75.8-25177.2-169.9171.9179.3174.30113.6E164 V166 P170E164-K168 WeakPolarHBondContact O-CB 3.38Å; E164-K168 PolarHBondContact O-N 3.48Å; V166-K168 VanDerWaalsContact C-N 3.27Å; V166-K168 PolarHBondContact O-N 3.24Å; K168-P170 VanDerWaalsContact C-CD 3.48Å
169H90.9Very high93.1Very high11 Ų1144.7 Ų44.75%0.05127%0.268CS..  trans-132.854.5-176.1-42.892.4000112.3L122 N127 W148 L152 K165 V166 N171L122-H169 HydrophobicContact CD2-CB 3.76Å; N127-H169 HydrophobicContact CB-CB 4.13Å; W148-H169 PolarHBondContact NE1-O 2.9Å; L152-H169 VanDerWaalsContact CD1-O 3.3Å; L152-H169 WeakPolarHBondContact CD1-O 3.37Å; K165-H169 PolarHBondContact O-N 3.01Å; K165-H169 PolarHBondContact O-ND1 3.34Å; V166-H169 CarbonylContact O-C 3.22Å; V166-H169 VanDerWaalsContact O-C 3.31Å; V166-H169 PolarHBondContact O-N 3.46Å; V166-H169 VanDerWaalsContact O-N 3.15Å; H169-N171 PolarHBondContact O-N 3.33Å; H169-N171 VanDerWaalsContact O-N 3.15Å
170P89.8Confident93.2Very high66 Ų6642 Ų4243%0.42924%0.24SC..SBendtrans-64.5-25.9-173.127.6-35.3000112.4A167 K168A167-P170 WeakPolarHBondContact O-CD 3.43Å; K168-P170 VanDerWaalsContact C-CD 3.48Å
171N90.9Very high93.5Very high44 Ų4439.4 Ų39.424%0.23522%0.222CC..SBendtrans-134.3156.2178.7-62.7-51.1000110H169 N346H169-N171 PolarHBondContact O-N 3.33Å; H169-N171 VanDerWaalsContact O-N 3.15Å; N171-N346 PolarHBondContact ND2-OD1 3.4Å
172I93.1Very high93.6Very high1 Ų138.8 Ų38.81%0.00522%0.218CC..  trans-104.8130.5166-169.2168.9000109.7L121 N127 L129 F144 R145 W148 I174L121-I172 HydrophobicContact CD1-CD1 3.98Å; N127-I172 CarbonylContact O-C 3.59Å; N127-I172 WeakPolarHBondContact O-CA 3.42Å; L129-I172 HydrophobicContact CB-CD1 4.2Å; L129-I172 HydrophobicContact CB-CG1 4.46Å; L129-I172 HydrophobicContact CD2-CD1 4.3Å; F144-I172 HydrophobicContact CD1-CD1 4.48Å; F144-I172 HydrophobicContact CE1-CD1 4.08Å; R145-I172 HydrophobicContact CB-CG2 4.09Å; R145-I172 HydrophobicContact CG-CG2 3.8Å; R145-I172 WeakPolarHBondContact CG-O 3.22Å; W148-I172 HydrophobicContact CB-CG2 3.86Å; W148-I172 HydrophobicContact CD2-CB 3.66Å; W148-I172 HydrophobicContact CD2-CG2 3.59Å; W148-I172 HydrophobicContact CE3-CB 3.93Å; W148-I172 HydrophobicContact CE3-CD1 3.97Å; W148-I172 HydrophobicContact CE3-CG2 3.71Å; W148-I172 HydrophobicContact CG-CB 4.03Å; W148-I172 HydrophobicContact CG-CG2 3.68Å; W148-I172 HydrophobicContact CH2-CB 4.44Å; W148-I172 HydrophobicContact CH2-CD1 3.92Å; W148-I172 HydrophobicContact CZ2-CB 4.21Å; W148-I172 HydrophobicContact CZ2-CD1 4.47Å; W148-I172 HydrophobicContact CZ3-CB 4.32Å; W148-I172 HydrophobicContact CZ3-CD1 3.64Å; W148-I172 HydrophobicContact CZ3-CG2 4.46Å; I172-I174 HydrophobicContact CG1-CG1 4.36Å; I172-I174 HydrophobicContact CG2-CD1 4.44Å; I172-I174 HydrophobicContact CG2-CG1 4.43Å
173K94.5Very high93.7Very high44 Ų4435.6 Ų35.619%0.19120%0.198CC..EExtended strand (participates in β ladder)trans-89.7135.6171.5-57.2-169.6-159.7177.30109.1N127 N128 L129 L340 T343N127-K173 PolarHBondContact O-N 3.44Å; N128-K173 CarbonylContact C-O 3.59Å; N128-K173 WeakPolarHBondContact OD1-CD 3.07Å; L129-K173 PolarHBondContact N-O 3.32Å; K173-L340 HydrophobicContact CB-CD2 3.7Å; K173-L340 WeakPolarHBondContact CD-O 3.47Å; K173-L340 PolarHBondContact NZ-O 3.34Å; K173-T343 WeakPolarHBondContact CE-O 3.38Å; K173-T343 PolarHBondContact NZ-O 3.03Å
174I95Very high93.7Very high7 Ų732.8 Ų32.84%0.03617%0.174CC..EExtended strand (participates in β ladder)trans-129.2134179.7-57.5-169.7000109.7L129 A141 R145 I172 P349L129-I174 HydrophobicContact CB-CG1 4.23Å; L129-I174 HydrophobicContact CD2-CD1 4.32Å; L129-I174 WeakPolarHBondContact O-CA 3.41Å; A141-I174 HydrophobicContact CB-CD1 4.18Å; A141-I174 HydrophobicContact CB-CG2 4.04Å; A141-I174 WeakPolarHBondContact O-CD1 3.47Å; R145-I174 HydrophobicContact CB-CD1 3.81Å; R145-I174 HydrophobicContact CB-CG1 4.41Å; I172-I174 HydrophobicContact CG1-CG1 4.36Å; I172-I174 HydrophobicContact CG2-CD1 4.44Å; I172-I174 HydrophobicContact CG2-CG1 4.43Å; I174-P349 HydrophobicContact CB-CB 4.49Å
175V96.5Very high93.5Very high2 Ų225.6 Ų25.61%0.01214%0.14CC..EExtended strand (participates in β ladder)trans-123.3132.4165.9175.80000109.6L129 V130 C131 A336 A339 L340 C350 I352L129-V175 PolarHBondContact O-N 2.81Å; V130-V175 WeakPolarHBondContact CA-O 3.47Å; C131-V175 PolarHBondContact N-O 3Å; V175-A336 HydrophobicContact CB-CB 4.4Å; V175-A336 HydrophobicContact CG1-CB 3.69Å; V175-A339 HydrophobicContact CG2-CB 3.98Å; V175-L340 HydrophobicContact CB-CD2 4.26Å; V175-L340 HydrophobicContact CB-CG 4.15Å; V175-L340 HydrophobicContact CG2-CD2 3.67Å; V175-L340 HydrophobicContact CG2-CG 3.63Å; V175-C350 WeakPolarHBondContact CA-O 3.16Å; V175-I352 HydrophobicContact CG1-CD1 3.77Å; V175-I352 HydrophobicContact CG1-CG1 3.58Å
176G96.4Very high93.4Very high0 Ų023.1 Ų23.10%013%0.131CC..EExtended strand (participates in β ladder)trans-97.8139.3178.900000113.2C131 L138 C350 V351 I352C131-G176 CarbonylContact O-C 3.47Å; C131-G176 WeakPolarHBondContact O-CA 3.14Å; L138-G176 VanDerWaalsContact CD2-CA 3.41Å; G176-C350 PolarHBondContact N-O 3.31Å; G176-V351 CarbonylContact O-C 3.47Å; G176-V351 VanDerWaalsContact O-CA 3.31Å; G176-V351 WeakPolarHBondContact O-CA 3.34Å; G176-I352 PolarHBondContact O-N 2.98Å
177L97.7Very high93.2Very high0 Ų022.4 Ų22.40%013%0.13CC..EExtended strand (participates in β ladder)trans-119.9129.9166-58.5-173.1000108.7A49 V53 V130 C131 I132 G133 G179 I192 M332 A336 I352A49-L177 HydrophobicContact CB-CD1 3.91Å; V53-L177 HydrophobicContact CG2-CD1 4.43Å; V130-L177 HydrophobicContact CG1-CD1 4.15Å; V130-L177 HydrophobicContact CG1-CG 4.2Å; C131-L177 PolarHBondContact O-N 3.44Å; I132-L177 WeakPolarHBondContact CA-O 3.41Å; I132-L177 HydrophobicContact CB-CB 4.45Å; I132-L177 HydrophobicContact CD1-CD1 4.16Å; I132-L177 HydrophobicContact CG1-CB 4.2Å; I132-L177 HydrophobicContact CG1-CD1 4.03Å; I132-L177 HydrophobicContact CG1-CG 4.42Å; I132-L177 HydrophobicContact CG2-CB 4.28Å; G133-L177 PolarHBondContact N-O 3.01Å; L177-G179 PolarHBondContact O-N 2.74Å; L177-I192 HydrophobicContact CB-CD1 4.46Å; L177-M332 HydrophobicContact CD2-CB 3.88Å; L177-A336 HydrophobicContact CD1-CB 4.37Å; L177-A336 HydrophobicContact CD2-CB 3.97Å; L177-A336 HydrophobicContact CG-CB 4.35Å; L177-I352 HydrophobicContact CD2-CB 3.54Å; L177-I352 HydrophobicContact CD2-CG1 3.67Å; L177-I352 HydrophobicContact CD2-CG2 4.45Å
178V96.5Very high93.2Very high3 Ų319.5 Ų19.52%0.01810%0.104CC..EExtended strand (participates in β ladder)trans-88.3101-176.2-163.60000110.4G133 L138 F185 T191 I192 V351G133-V178 CarbonylContact O-C 3.55Å; G133-V178 VanDerWaalsContact O-CA 3.3Å; G133-V178 WeakPolarHBondContact O-CA 3.42Å; L138-V178 HydrophobicContact CD1-CG2 3.85Å; V178-F185 HydrophobicContact CG1-CB 3.68Å; V178-F185 HydrophobicContact CG1-CD1 4.3Å; V178-F185 HydrophobicContact CG1-CD2 4.36Å; V178-F185 HydrophobicContact CG1-CG 3.87Å; V178-F185 HydrophobicContact CG2-CB 4.44Å; V178-F185 HydrophobicContact CG2-CD1 3.5Å; V178-F185 VanDerWaalsContact CG2-CD1 3.5Å; V178-F185 HydrophobicContact CG2-CD2 4.48Å; V178-F185 HydrophobicContact CG2-CE1 3.73Å; V178-F185 HydrophobicContact CG2-CG 3.9Å; V178-F185 HydrophobicContact CG2-CZ 4.33Å; V178-T191 HydrophobicContact CB-CG2 3.9Å; V178-T191 HydrophobicContact CG1-CG2 3.39Å; V178-I192 PolarHBondContact O-N 2.9Å; V178-V351 HydrophobicContact CG2-CG1 3.59Å
179G96.3Very high93.2Very high1 Ų115.5 Ų15.51%0.019%0.09CC..EExtended strand (participates in β ladder)trans-99.4102.8171.400000110.4S43 G133 G134 L177S43-G179 WeakPolarHBondContact OG-CA 3.35Å; G133-G179 CarbonylContact C-O 3.54Å; G133-G179 PolarHBondContact O-N 3.39Å; G134-G179 PolarHBondContact N-O 3.34Å; L177-G179 PolarHBondContact O-N 2.74Å
180S95.8Very high93.4Very high7 Ų716 Ų165%0.0499%0.092CC..EExtended strand (participates in β ladder)trans-158147.3179-175.90000109.7S43 D182 T191 I192 T194S43-S180 PolarHBondContact OG-N 3.06Å; S180-D182 PolarHBondContact OG-N 3.44Å; S180-D182 PolarHBondContact OG-OD2 3.45Å; S180-T191 WeakPolarHBondContact O-CB 3.15Å; S180-T191 PolarHBondContact O-OG1 3.5Å; S180-I192 CarbonylContact C-O 3.56Å; S180-I192 PolarHBondContact N-O 3.41Å; S180-I192 CarbonylContact O-C 3.53Å; S180-T194 PolarHBondContact O-N 3.07Å; S180-T194 PolarHBondContact O-OG1 3.13Å
181I97.1Very high93.7Very high0 Ų012.9 Ų12.90%07%0.072CC..SBendtrans-82.6-23.6170.766.8166.6000111.9N183 T194 A197 M224 L231 Q316 R317I181-N183 VanDerWaalsContact C-N 3.32Å; I181-N183 PolarHBondContact O-N 3.41Å; I181-T194 VanDerWaalsContact C-OG1 3.3Å; I181-T194 WeakPolarHBondContact O-CA 3.44Å; I181-T194 WeakPolarHBondContact O-CB 3.19Å; I181-T194 PolarHBondContact O-OG1 3.45Å; I181-A197 HydrophobicContact CB-CB 3.71Å; I181-A197 HydrophobicContact CD1-CB 4.48Å; I181-A197 HydrophobicContact CG2-CB 3.91Å; I181-M224 HydrophobicContact CD1-CB 3.91Å; I181-M224 HydrophobicContact CD1-SD 3.94Å; I181-L231 HydrophobicContact CD1-CD1 4.37Å; I181-L231 HydrophobicContact CG1-CD1 4.4Å; I181-Q316 HydrophobicContact CD1-CB 4.35Å; I181-R317 HydrophobicContact CD1-CG 3.84Å
182D95.3Very high94Very high0 Ų010.8 Ų10.80%06%0.061CC..SBendtrans-74.5-21.6-164.4-55.4-37.1000113.1S180 D184 G225 R226S180-D182 PolarHBondContact OG-N 3.44Å; S180-D182 PolarHBondContact OG-OD2 3.45Å; D182-D184 HydrophobicContact CB-CB 4.13Å; D182-D184 PolarHBondContact O-N 2.86Å; D182-G225 VanDerWaalsContact OD1-CA 3.3Å; D182-G225 WeakPolarHBondContact OD1-CA 3.31Å; D182-R226 IonicContact OD2-CZ 2.76Å
183N94.8Very high94.2Very high17 Ų1710.7 Ų10.79%0.0916%0.061CC..  trans5238.1-170-154.229.3000113.6I181 D189 M190 T191 T194 Y230I181-N183 VanDerWaalsContact C-N 3.32Å; I181-N183 PolarHBondContact O-N 3.41Å; N183-D189 PolarHBondContact ND2-O 3.02Å; N183-M190 VanDerWaalsContact OD1-CA 3.31Å; N183-M190 WeakPolarHBondContact OD1-CA 3.48Å; N183-T191 WeakPolarHBondContact CA-OG1 3.37Å; N183-T191 PolarHBondContact N-OG1 3.45Å; N183-T191 PolarHBondContact OD1-N 3.36Å; N183-T191 VanDerWaalsContact OD1-N 3.11Å; N183-T194 HydrophobicContact CB-CG2 3.79Å; N183-T194 PolarHBondContact N-OG1 3.31Å; N183-Y230 HydrophobicContact CB-CD1 3.66Å; N183-Y230 HydrophobicContact CB-CE1 4.2Å; N183-Y230 HydrophobicContact CB-CG 3.95Å; N183-Y230 WeakPolarHBondContact ND2-CE1 3.42Å
184D91.8Very high94.3Very high9 Ų98.6 Ų8.65%0.0485%0.052CC..  trans-94.3-5.3-173.766.9-18.9000114D182 R226 C228 R390D182-D184 HydrophobicContact CB-CB 4.13Å; D182-D184 PolarHBondContact O-N 2.86Å; D184-R226 IonicContact OD2-NH1 2.73Å; D184-R226 PolarHBondContact OD2-NH1 2.82Å; D184-R226 VanDerWaalsContact OD2-NH1 3.13Å; D184-C228 HydrophobicContact CB-CB 3.82Å; D184-R390 PolarHBondContact O-NH1 2.83Å; D184-R390 VanDerWaalsContact O-NH1 3.15Å
185F90.1Very high94.4Very high4 Ų48.4 Ų8.42%0.0185%0.05CC..  trans-85115.7-177-167.9-96.1000112.5D135 L138 V178 G187 T188 T191 V351 L364 C367D135-F185 HydrophobicContact CB-CD2 3.97Å; D135-F185 HydrophobicContact CB-CE2 4.44Å; L138-F185 HydrophobicContact CD1-CD2 4.49Å; L138-F185 HydrophobicContact CD1-CE2 3.85Å; L138-F185 HydrophobicContact CD1-CZ 3.86Å; V178-F185 HydrophobicContact CG1-CB 3.68Å; V178-F185 HydrophobicContact CG1-CD1 4.3Å; V178-F185 HydrophobicContact CG1-CD2 4.36Å; V178-F185 HydrophobicContact CG1-CG 3.87Å; V178-F185 HydrophobicContact CG2-CB 4.44Å; V178-F185 HydrophobicContact CG2-CD1 3.5Å; V178-F185 VanDerWaalsContact CG2-CD1 3.5Å; V178-F185 HydrophobicContact CG2-CD2 4.48Å; V178-F185 HydrophobicContact CG2-CE1 3.73Å; V178-F185 HydrophobicContact CG2-CG 3.9Å; V178-F185 HydrophobicContact CG2-CZ 4.33Å; F185-G187 PolarHBondContact O-N 3.37Å; F185-T188 HydrophobicContact CD1-CG2 4.45Å; F185-T191 HydrophobicContact CB-CG2 4.13Å; F185-V351 HydrophobicContact CE1-CG1 4.02Å; F185-V351 HydrophobicContact CE1-CG2 4.3Å; F185-V351 HydrophobicContact CZ-CG2 4.1Å; F185-L364 HydrophobicContact CZ-CD1 4.46Å; F185-C367 HydrophobicContact CD1-CB 4.44Å; F185-C367 HydrophobicContact CE1-CB 3.44Å; F185-C367 VanDerWaalsContact CE1-CB 3.44Å; F185-C367 HydrophobicContact CE2-CB 4.4Å; F185-C367 HydrophobicContact CZ-CB 3.41Å; F185-C367 VanDerWaalsContact CZ-CB 3.41Å
186C88.1Confident94.5Very high10 Ų108.3 Ų8.37%0.0685%0.05CC..THydrogen-bonded Turntrans-72.8124.4-178.6-660000111.3C367 R370 T371C186-C367 WeakPolarHBondContact O-CA 3.34Å; C186-C367 VanDerWaalsContact O-CB 3.23Å; C186-C367 WeakPolarHBondContact O-CB 3.35Å; C186-C367 PolarHBondContact O-SG 3.41Å; C186-R370 HydrophobicContact CB-CB 3.6Å; C186-T371 WeakPolarHBondContact CB-OG1 3.33Å; C186-T371 PolarHBondContact N-OG1 3.44Å
187G86.3Confident94.6Very high17 Ų178.3 Ų8.318%0.1755%0.05CC..THydrogen-bonded Turntrans119.30.3176.400000114.8F185 A353 H355F185-G187 PolarHBondContact O-N 3.37Å; G187-A353 WeakPolarHBondContact O-CB 3.38Å; G187-H355 PolarHBondContact O-NE2 2.67Å
188T91.4Very high94.6Very high15 Ų158.5 Ų8.59%0.0925%0.051CC..  trans-127.1147.9165.7-169.70000109.4F185 M190 T191 I354F185-T188 HydrophobicContact CD1-CG2 4.45Å; T188-M190 VanDerWaalsContact C-N 3.34Å; T188-M190 WeakPolarHBondContact CG2-O 3.47Å; T188-M190 PolarHBondContact OG1-O 3.28Å; T188-T191 HydrophobicContact CG2-CG2 3.7Å; T188-I354 PolarHBondContact OG1-N 2.94Å; T188-I354 VanDerWaalsContact OG1-N 3.15Å
189D89.9Confident94.7Very high68 Ų689.8 Ų9.836%0.3646%0.057SC..SBendtrans-74.7-29.3176.4-69.2-18.5000111.7N183 I354 H355 G356N183-D189 PolarHBondContact ND2-O 3.02Å; D189-I354 HydrophobicContact CB-CG2 4.44Å; D189-I354 WeakPolarHBondContact CB-O 3.27Å; D189-I354 PolarHBondContact N-O 2.85Å; D189-H355 IonicContact OD1-CD2 3.7Å; D189-H355 VanDerWaalsContact OD2-CA 3.26Å; D189-H355 WeakPolarHBondContact OD2-CA 3.49Å; D189-G356 PolarHBondContact OD2-N 3.48Å
190M93.3Very high94.8Very high20 Ų2012.8 Ų12.810%0.0997%0.068CC..  trans-145.8138.5178.8-160.970.974.800110.5N183 T188 T194 Y230 F324 I354N183-M190 VanDerWaalsContact OD1-CA 3.31Å; N183-M190 WeakPolarHBondContact OD1-CA 3.48Å; T188-M190 VanDerWaalsContact C-N 3.34Å; T188-M190 WeakPolarHBondContact CG2-O 3.47Å; T188-M190 PolarHBondContact OG1-O 3.28Å; M190-T194 HydrophobicContact SD-CG2 3.44Å; M190-T194 WeakPolarHBondContact SD-CG2 3.29Å; M190-Y230 HydrophobicContact CE-CE1 4.41Å; M190-Y230 WeakPolarHBondContact CE-OH 3.5Å; M190-Y230 HydrophobicContact SD-CE1 4.03Å; M190-F324 HydrophobicContact CB-CE1 4.09Å; M190-F324 HydrophobicContact CB-CZ 4.2Å; M190-F324 HydrophobicContact CG-CE1 3.69Å; M190-F324 HydrophobicContact CG-CZ 4.24Å; M190-I354 HydrophobicContact CB-CG2 4.23Å
191T95.9Very high94.9Very high1 Ų112.5 Ų12.51%0.0067%0.066CC..  trans-93.8151.8169.752.70000111.4V178 S180 N183 F185 T188 G193 T194V178-T191 HydrophobicContact CB-CG2 3.9Å; V178-T191 HydrophobicContact CG1-CG2 3.39Å; S180-T191 WeakPolarHBondContact O-CB 3.15Å; S180-T191 PolarHBondContact O-OG1 3.5Å; N183-T191 WeakPolarHBondContact CA-OG1 3.37Å; N183-T191 PolarHBondContact N-OG1 3.45Å; N183-T191 PolarHBondContact OD1-N 3.36Å; N183-T191 VanDerWaalsContact OD1-N 3.11Å; F185-T191 HydrophobicContact CB-CG2 4.13Å; T188-T191 HydrophobicContact CG2-CG2 3.7Å; T191-G193 PolarHBondContact O-N 3.33Å; T191-G193 VanDerWaalsContact O-N 3.15Å; T191-T194 PolarHBondContact O-N 3.24Å; T191-T194 PolarHBondContact OG1-OG1 3.49Å
192I97.7Very high94.9Very high0 Ų012.7 Ų12.70%07%0.067CC..EExtended strand (participates in β ladder)trans-65.2115.8179.5-59.3165.6000108.7S43 G45 A49 L177 V178 S180 L328 M332S43-I192 VanDerWaalsContact CB-O 3.3Å; S43-I192 WeakPolarHBondContact CB-O 3.49Å; S43-I192 PolarHBondContact OG-O 2.93Å; G45-I192 VanDerWaalsContact C-CG2 3.49Å; A49-I192 HydrophobicContact CB-CD1 4.15Å; L177-I192 HydrophobicContact CB-CD1 4.46Å; V178-I192 PolarHBondContact O-N 2.9Å; S180-I192 CarbonylContact C-O 3.56Å; S180-I192 PolarHBondContact N-O 3.41Å; S180-I192 CarbonylContact O-C 3.53Å; I192-L328 HydrophobicContact CG1-CD2 3.85Å; I192-L328 HydrophobicContact CG1-CG 4.06Å; I192-M332 HydrophobicContact CD1-SD 3.88Å; I192-M332 HydrophobicContact CG1-SD 3.92Å
193G97.3Very high94.9Very high0 Ų017.8 Ų17.80%09%0.09CC..EExtended strand (participates in β ladder)trans110.8-14.9177.600000114.8Q44 T191 D195 T196 A197 D325Q44-G193 WeakPolarHBondContact O-CA 3.45Å; Q44-G193 PolarHBondContact O-N 2.96Å; T191-G193 PolarHBondContact O-N 3.33Å; T191-G193 VanDerWaalsContact O-N 3.15Å; G193-D195 PolarHBondContact O-N 2.92Å; G193-T196 PolarHBondContact O-N 3Å; G193-A197 WeakPolarHBondContact O-CB 3.26Å; G193-A197 PolarHBondContact O-N 3Å; G193-D325 WeakPolarHBondContact CA-OD2 3.5Å; G193-D325 PolarHBondContact N-OD1 3.43Å; G193-D325 PolarHBondContact N-OD2 3.29Å
194T97.4Very high95Very high0 Ų018.1 Ų18.10%010%0.095CC..Hα-helixtrans-62.9-43.4178.8-66.40000112S180 I181 N183 M190 T191 A197 L198 Y230 L231S180-T194 PolarHBondContact O-N 3.07Å; S180-T194 PolarHBondContact O-OG1 3.13Å; I181-T194 VanDerWaalsContact C-OG1 3.3Å; I181-T194 WeakPolarHBondContact O-CA 3.44Å; I181-T194 WeakPolarHBondContact O-CB 3.19Å; I181-T194 PolarHBondContact O-OG1 3.45Å; N183-T194 HydrophobicContact CB-CG2 3.79Å; N183-T194 PolarHBondContact N-OG1 3.31Å; M190-T194 HydrophobicContact SD-CG2 3.44Å; M190-T194 WeakPolarHBondContact SD-CG2 3.29Å; T191-T194 PolarHBondContact O-N 3.24Å; T191-T194 PolarHBondContact OG1-OG1 3.49Å; T194-A197 PolarHBondContact O-N 3.22Å; T194-L198 HydrophobicContact CG2-CD1 4.45Å; T194-L198 WeakPolarHBondContact O-CG 3.41Å; T194-L198 PolarHBondContact O-N 2.68Å; T194-Y230 HydrophobicContact CG2-CD1 3.75Å; T194-Y230 HydrophobicContact CG2-CE1 3.59Å; T194-L231 HydrophobicContact CG2-CD2 3.93Å
195D97.6Very high95.1Very high2 Ų217.7 Ų17.71%0.0119%0.093CC..Hα-helixtrans-64.6-44.1-179.5-177.172.6000110.7G193 A197 L198 H199 S322 F324G193-D195 PolarHBondContact O-N 2.92Å; D195-A197 VanDerWaalsContact C-N 3.33Å; D195-A197 PolarHBondContact O-N 3.38Å; D195-L198 WeakPolarHBondContact O-CB 3.49Å; D195-L198 PolarHBondContact O-N 3.47Å; D195-L198 VanDerWaalsContact O-N 3.14Å; D195-H199 PolarHBondContact O-CD2 3.05Å; D195-H199 VanDerWaalsContact O-CD2 3.26Å; D195-H199 PolarHBondContact O-N 2.89Å; D195-H199 IonicContact OD2-CD2 3.09Å; D195-H199 IonicContact OD2-NE2 3.21Å; D195-S322 WeakPolarHBondContact OD2-CB 3.31Å; D195-S322 PolarHBondContact OD2-OG 3.36Å; D195-F324 HydrophobicContact CB-CB 4.35Å; D195-F324 HydrophobicContact CB-CD1 3.74Å; D195-F324 HydrophobicContact CB-CG 4.35Å
196T98.3Very high95.3Very high1 Ų119 Ų191%0.00610%0.1CC..Hα-helixtrans-61.7-40.4174.9-53.90000112.2Q44 G193 L198 H199 R200 N320 P321 S322 D325Q44-T196 HydrophobicContact CB-CG2 3.59Å; Q44-T196 HydrophobicContact CG-CG2 3.53Å; G193-T196 PolarHBondContact O-N 3Å; T196-L198 VanDerWaalsContact C-N 3.32Å; T196-L198 PolarHBondContact O-N 2.97Å; T196-H199 WeakPolarHBondContact O-CB 3.05Å; T196-H199 PolarHBondContact O-N 2.76Å; T196-H199 VanDerWaalsContact O-N 3.11Å; T196-R200 WeakPolarHBondContact O-CG 3.42Å; T196-R200 PolarHBondContact O-N 2.87Å; T196-R200 VanDerWaalsContact O-N 3.07Å; T196-N320 WeakPolarHBondContact CG2-O 3.42Å; T196-P321 WeakPolarHBondContact OG1-CA 3.37Å; T196-S322 PolarHBondContact OG1-N 3.47Å; T196-D325 VanDerWaalsContact CB-OD2 3.29Å; T196-D325 WeakPolarHBondContact CB-OD2 3.41Å; T196-D325 PolarHBondContact N-OD2 3.46Å; T196-D325 PolarHBondContact OG1-OD2 3.01Å
197A98.3Very high95.5Very high0 Ų021.5 Ų21.50%012%0.122CC..Hα-helixtrans-60.9-41.7175.100000111.7I181 G193 T194 D195 H199 R200 I201 L231 Q316I181-A197 HydrophobicContact CB-CB 3.71Å; I181-A197 HydrophobicContact CD1-CB 4.48Å; I181-A197 HydrophobicContact CG2-CB 3.91Å; G193-A197 WeakPolarHBondContact O-CB 3.26Å; G193-A197 PolarHBondContact O-N 3Å; T194-A197 PolarHBondContact O-N 3.22Å; D195-A197 VanDerWaalsContact C-N 3.33Å; D195-A197 PolarHBondContact O-N 3.38Å; A197-H199 VanDerWaalsContact C-N 3.3Å; A197-H199 PolarHBondContact O-N 2.89Å; A197-R200 WeakPolarHBondContact O-CB 3.45Å; A197-R200 PolarHBondContact O-N 3.18Å; A197-R200 VanDerWaalsContact O-N 3.12Å; A197-I201 VanDerWaalsContact O-CG1 3.32Å; A197-I201 WeakPolarHBondContact O-CG1 3.23Å; A197-I201 PolarHBondContact O-N 3.02Å; A197-L231 HydrophobicContact CB-CD1 4.34Å; A197-L231 HydrophobicContact CB-CD2 4.07Å; A197-Q316 WeakPolarHBondContact CB-O 3.35Å
198L98.2Very high95.8Very high4 Ų421.5 Ų21.52%0.02112%0.119CC..Hα-helixtrans-59.7-40172.5-71.2169.7000112T194 D195 T196 R200 I201 I202 Y230 L231 V234 P691T194-L198 HydrophobicContact CG2-CD1 4.45Å; T194-L198 WeakPolarHBondContact O-CG 3.41Å; T194-L198 PolarHBondContact O-N 2.68Å; D195-L198 WeakPolarHBondContact O-CB 3.49Å; D195-L198 PolarHBondContact O-N 3.47Å; D195-L198 VanDerWaalsContact O-N 3.14Å; T196-L198 VanDerWaalsContact C-N 3.32Å; T196-L198 PolarHBondContact O-N 2.97Å; L198-R200 VanDerWaalsContact C-N 3.3Å; L198-R200 PolarHBondContact O-N 3.47Å; L198-I201 PolarHBondContact O-N 2.8Å; L198-I202 WeakPolarHBondContact O-CG1 3.47Å; L198-I202 PolarHBondContact O-N 2.91Å; L198-Y230 HydrophobicContact CD1-CE1 4.34Å; L198-L231 HydrophobicContact CD2-CD2 3.71Å; L198-L231 HydrophobicContact CG-CD2 3.68Å; L198-V234 HydrophobicContact CD1-CB 4.23Å; L198-V234 HydrophobicContact CD1-CG1 3.7Å; L198-V234 HydrophobicContact CD2-CB 3.91Å; L198-V234 HydrophobicContact CD2-CG1 3.94Å; L198-V234 HydrophobicContact CG-CG1 4.48Å; L198-P691 HydrophobicContact CB-CB 3.87Å; L198-P691 HydrophobicContact CB-CG 3.97Å; L198-P691 WeakPolarHBondContact O-CG 3.22Å
199H98Very high95.7Very high29 Ų2921.1 Ų21.113%0.13412%0.116CC..Hα-helixtrans-59.3-42.2174.7-85.2-119.1000111.6D195 T196 A197 E203 T690 P691D195-H199 PolarHBondContact O-CD2 3.05Å; D195-H199 VanDerWaalsContact O-CD2 3.26Å; D195-H199 PolarHBondContact O-N 2.89Å; D195-H199 IonicContact OD2-CD2 3.09Å; D195-H199 IonicContact OD2-NE2 3.21Å; T196-H199 WeakPolarHBondContact O-CB 3.05Å; T196-H199 PolarHBondContact O-N 2.76Å; T196-H199 VanDerWaalsContact O-N 3.11Å; A197-H199 VanDerWaalsContact C-N 3.3Å; A197-H199 PolarHBondContact O-N 2.89Å; H199-E203 WeakPolarHBondContact O-CB 3.29Å; H199-E203 PolarHBondContact O-N 3.06Å; H199-T690 VanDerWaalsContact CE1-CG2 3.41Å; H199-T690 WeakPolarHBondContact CE1-CG2 3.5Å; H199-P691 HydrophobicContact CB-CG 4.39Å; H199-P691 VanDerWaalsContact CD2-CD 3.42Å; H199-P691 WeakPolarHBondContact CD2-CD 3.42Å
200R97.8Very high95.5Very high65 Ų6521.4 Ų21.425%0.24512%0.123CC..Hα-helixtrans-66.3-40.9177.8-59.5-61.789.3-152.2-6.2111.8T196 A197 L198 E203 A204 V315T196-R200 WeakPolarHBondContact O-CG 3.42Å; T196-R200 PolarHBondContact O-N 2.87Å; T196-R200 VanDerWaalsContact O-N 3.07Å; A197-R200 WeakPolarHBondContact O-CB 3.45Å; A197-R200 PolarHBondContact O-N 3.18Å; A197-R200 VanDerWaalsContact O-N 3.12Å; L198-R200 VanDerWaalsContact C-N 3.3Å; L198-R200 PolarHBondContact O-N 3.47Å; R200-E203 IonicContact CZ-OE2 2.67Å; R200-E203 IonicContact NH1-OE1 3.06Å; R200-E203 IonicContact NH1-OE2 3.9Å; R200-E203 PolarHBondContact NH1-OE2 3.48Å; R200-E203 IonicContact NH2-OE2 3.19Å; R200-E203 PolarHBondContact NH2-OE2 2.95Å; R200-A204 WeakPolarHBondContact O-CB 3.18Å; R200-A204 PolarHBondContact O-N 2.87Å; R200-A204 VanDerWaalsContact O-N 3.14Å; R200-V315 VanDerWaalsContact CG-O 3.26Å; R200-V315 WeakPolarHBondContact CG-O 3.42Å
201I98.1Very high95.3Very high0 Ų023 Ų230%013%0.134CC..Hα-helixtrans-63.3-49.8177.7-65.5164.1000110.5A197 L198 A204 I205 V223 L231 A235 L312 Q316A197-I201 VanDerWaalsContact O-CG1 3.32Å; A197-I201 WeakPolarHBondContact O-CG1 3.23Å; A197-I201 PolarHBondContact O-N 3.02Å; L198-I201 PolarHBondContact O-N 2.8Å; I201-A204 PolarHBondContact O-N 3.44Å; I201-I205 HydrophobicContact CG2-CD1 3.68Å; I201-I205 HydrophobicContact CG2-CG1 4.4Å; I201-I205 WeakPolarHBondContact O-CG1 3.4Å; I201-I205 PolarHBondContact O-N 3.5Å; I201-V223 HydrophobicContact CD1-CB 4.27Å; I201-V223 HydrophobicContact CD1-CG1 4.3Å; I201-V223 HydrophobicContact CG1-CG1 4.28Å; I201-V223 HydrophobicContact CG2-CG1 3.87Å; I201-L231 HydrophobicContact CD1-CB 3.9Å; I201-L231 HydrophobicContact CD1-CD1 4.28Å; I201-L231 HydrophobicContact CD1-CD2 4.17Å; I201-L231 HydrophobicContact CD1-CG 4.35Å; I201-A235 HydrophobicContact CG2-CB 3.58Å; I201-L312 HydrophobicContact CB-CD1 4.21Å; I201-L312 HydrophobicContact CG1-CD1 3.95Å; I201-L312 HydrophobicContact CG2-CD1 4.19Å; I201-Q316 HydrophobicContact CG1-CG 3.96Å
202I97.1Very high94.8Very high4 Ų423 Ų232%0.02113%0.133CC..Hα-helixtrans-66.2-40.3-178.6-66.9-57.6000111.8L198 A204 I205 D206 A235 A238 P691L198-I202 WeakPolarHBondContact O-CG1 3.47Å; L198-I202 PolarHBondContact O-N 2.91Å; I202-A204 VanDerWaalsContact C-N 3.29Å; I202-A204 PolarHBondContact O-N 2.9Å; I202-I205 PolarHBondContact O-N 2.8Å; I202-D206 WeakPolarHBondContact O-CB 3.39Å; I202-D206 PolarHBondContact O-N 3.48Å; I202-A235 HydrophobicContact CD1-CB 4.36Å; I202-A238 HydrophobicContact CD1-CB 3.74Å; I202-A238 HydrophobicContact CG1-CB 4.29Å; I202-P691 HydrophobicContact CB-CG 4.04Å; I202-P691 HydrophobicContact CG1-CB 3.9Å; I202-P691 HydrophobicContact CG1-CG 3.74Å
203E95.7Very high94.3Very high107 Ų10726 Ų2650%0.515%0.148SC..Hα-helixtrans-58.5-42.8174.1-177.3178.714900111.8H199 R200 A207H199-E203 WeakPolarHBondContact O-CB 3.29Å; H199-E203 PolarHBondContact O-N 3.06Å; R200-E203 IonicContact CZ-OE2 2.67Å; R200-E203 IonicContact NH1-OE1 3.06Å; R200-E203 IonicContact NH1-OE2 3.9Å; R200-E203 PolarHBondContact NH1-OE2 3.48Å; R200-E203 IonicContact NH2-OE2 3.19Å; R200-E203 PolarHBondContact NH2-OE2 2.95Å; E203-A207 WeakPolarHBondContact O-CB 3.19Å; E203-A207 PolarHBondContact O-N 2.77Å
204A96.1Very high93.8Very high24 Ų2430.1 Ų30.120%0.19818%0.176CC..Hα-helixtrans-67.8-40.9178.200000112.5R200 I201 I202 A207 V208 L312R200-A204 WeakPolarHBondContact O-CB 3.18Å; R200-A204 PolarHBondContact O-N 2.87Å; R200-A204 VanDerWaalsContact O-N 3.14Å; I201-A204 PolarHBondContact O-N 3.44Å; I202-A204 VanDerWaalsContact C-N 3.29Å; I202-A204 PolarHBondContact O-N 2.9Å; A204-A207 PolarHBondContact O-N 3Å; A204-V208 WeakPolarHBondContact O-CB 3.43Å; A204-V208 VanDerWaalsContact O-CG2 3.32Å; A204-V208 WeakPolarHBondContact O-CG2 3.39Å; A204-V208 PolarHBondContact O-N 3.14Å; A204-L312 HydrophobicContact CB-CD1 4.16Å; A204-L312 HydrophobicContact CB-CD2 3.41Å; A204-L312 VanDerWaalsContact CB-CD2 3.41Å; A204-L312 HydrophobicContact CB-CG 4.45Å
205I95.6Very high93.3Very high0 Ų035.1 Ų35.10%020%0.2CC..Hα-helixtrans-65.7-46.1177.3-66.5169.1000110.7I201 I202 A207 V208 Q209 V221 A235 I275 I277I201-I205 HydrophobicContact CG2-CD1 3.68Å; I201-I205 HydrophobicContact CG2-CG1 4.4Å; I201-I205 WeakPolarHBondContact O-CG1 3.4Å; I201-I205 PolarHBondContact O-N 3.5Å; I202-I205 PolarHBondContact O-N 2.8Å; I205-A207 VanDerWaalsContact C-N 3.26Å; I205-A207 PolarHBondContact O-N 2.9Å; I205-V208 PolarHBondContact O-N 3.4Å; I205-V208 VanDerWaalsContact O-N 3.15Å; I205-Q209 WeakPolarHBondContact O-CB 3.27Å; I205-Q209 PolarHBondContact O-N 3.33Å; I205-V221 HydrophobicContact CG1-CG1 4.28Å; I205-V221 HydrophobicContact CG1-CG2 4.44Å; I205-A235 HydrophobicContact CD1-CB 4.46Å; I205-I275 HydrophobicContact CG2-CG2 4.21Å; I205-I277 HydrophobicContact CD1-CD1 3.67Å; I205-I277 HydrophobicContact CD1-CG1 4.27Å
206D93.8Very high92.8Very high32 Ų3240 Ų4017%0.17122%0.222CC..Hα-helixtrans-59.1-40.2177.4-70.2-9.7000110.8I202 Q209 R694I202-D206 WeakPolarHBondContact O-CB 3.39Å; I202-D206 PolarHBondContact O-N 3.48Å; D206-Q209 PolarHBondContact O-N 3.41Å; D206-R694 IonicContact OD1-CZ 3.93Å; D206-R694 IonicContact OD1-NH1 3.62Å; D206-R694 PolarHBondContact OD1-NH1 3.45Å; D206-R694 IonicContact OD1-NH2 3.17Å; D206-R694 IonicContact OD2-CZ 2.6Å; D206-R694 IonicContact OD2-NH1 3.24Å; D206-R694 PolarHBondContact OD2-NH1 2.87Å; D206-R694 IonicContact OD2-NH2 3.22Å; D206-R694 PolarHBondContact OD2-NH2 3.34Å
207A92.8Very high92.5Very high62 Ų6242.6 Ų42.651%0.51223%0.232SC..Hα-helixtrans-63.6-45.7175.400000112.1E203 A204 I205 Q209 S210E203-A207 WeakPolarHBondContact O-CB 3.19Å; E203-A207 PolarHBondContact O-N 2.77Å; A204-A207 PolarHBondContact O-N 3Å; I205-A207 VanDerWaalsContact C-N 3.26Å; I205-A207 PolarHBondContact O-N 2.9Å; A207-Q209 VanDerWaalsContact C-N 3.31Å; A207-Q209 PolarHBondContact O-N 3.37Å; A207-S210 PolarHBondContact O-N 3.07Å; A207-S210 PolarHBondContact O-OG 3.02Å
208V91.9Very high92.4Very high18 Ų1842.6 Ų42.611%0.10923%0.232CC..Hα-helixtrans-63.3-37.2176.7166.40000111.6A204 I205 S210 T211 A212 F219 I275A204-V208 WeakPolarHBondContact O-CB 3.43Å; A204-V208 VanDerWaalsContact O-CG2 3.32Å; A204-V208 WeakPolarHBondContact O-CG2 3.39Å; A204-V208 PolarHBondContact O-N 3.14Å; I205-V208 PolarHBondContact O-N 3.4Å; I205-V208 VanDerWaalsContact O-N 3.15Å; V208-S210 VanDerWaalsContact C-N 3.28Å; V208-S210 PolarHBondContact O-N 2.92Å; V208-T211 WeakPolarHBondContact O-CG2 3.4Å; V208-T211 PolarHBondContact O-N 2.89Å; V208-A212 VanDerWaalsContact O-CB 3.31Å; V208-A212 WeakPolarHBondContact O-CB 3.4Å; V208-A212 PolarHBondContact O-N 3.08Å; V208-F219 HydrophobicContact CG1-CB 3.84Å; V208-F219 HydrophobicContact CG1-CD1 3.34Å; V208-F219 HydrophobicContact CG1-CD2 3.62Å; V208-F219 HydrophobicContact CG1-CE1 3.66Å; V208-F219 HydrophobicContact CG1-CE2 3.93Å; V208-F219 HydrophobicContact CG1-CG 3.31Å; V208-F219 HydrophobicContact CG1-CZ 3.94Å; V208-I275 HydrophobicContact CG1-CD1 4.36Å
209Q88.2Confident92.3Very high7 Ų743 Ų433%0.03323%0.234CC..Hα-helixtrans-60.1-38.4-176.8-171.5161.4-4.500112.1I205 D206 A207 A212 Q213 N479 M482I205-Q209 WeakPolarHBondContact O-CB 3.27Å; I205-Q209 PolarHBondContact O-N 3.33Å; D206-Q209 PolarHBondContact O-N 3.41Å; A207-Q209 VanDerWaalsContact C-N 3.31Å; A207-Q209 PolarHBondContact O-N 3.37Å; Q209-A212 PolarHBondContact O-N 3.35Å; Q209-Q213 HydrophobicContact CG-CG 4.49Å; Q209-Q213 WeakPolarHBondContact O-CB 3.47Å; Q209-Q213 WeakPolarHBondContact O-CG 3.31Å; Q209-Q213 PolarHBondContact O-N 2.9Å; Q209-N479 PolarHBondContact NE2-OD1 3.49Å; Q209-M482 VanDerWaalsContact CD-SD 3.54Å; Q209-M482 HydrophobicContact CG-SD 4.37Å; Q209-M482 PolarHBondContact OE1-SD 3.15Å
210S85.9Confident92.3Very high73 Ų7341.7 Ų41.751%0.5123%0.227SC..Hα-helixtrans-60.8-46.8177.670.70000113.1A207 V208 S214A207-S210 PolarHBondContact O-N 3.07Å; A207-S210 PolarHBondContact O-OG 3.02Å; V208-S210 VanDerWaalsContact C-N 3.28Å; V208-S210 PolarHBondContact O-N 2.92Å; S210-S214 PolarHBondContact O-N 3.17Å; S210-S214 PolarHBondContact O-OG 3.2Å
211T88.9Confident92.3Very high54 Ų5438.7 Ų38.733%0.33122%0.216SC..Hα-helixtrans-73.1-34177.6-175.50000111.7V208 Q213 S214 H215 F219V208-T211 WeakPolarHBondContact O-CG2 3.4Å; V208-T211 PolarHBondContact O-N 2.89Å; T211-Q213 PolarHBondContact O-N 3.25Å; T211-S214 PolarHBondContact O-N 2.93Å; T211-H215 PolarHBondContact O-CD2 3.31Å; T211-H215 PolarHBondContact O-N 3.07Å; T211-F219 HydrophobicContact CG2-CZ 4.06Å
212A87Confident92.3Very high0 Ų041.2 Ų41.20%023%0.228CC..Hα-helixtrans-63.2-42.7176.800000111.7V208 Q209 S214 H215 Q216 R217 F219 V273V208-A212 VanDerWaalsContact O-CB 3.31Å; V208-A212 WeakPolarHBondContact O-CB 3.4Å; V208-A212 PolarHBondContact O-N 3.08Å; Q209-A212 PolarHBondContact O-N 3.35Å; A212-S214 VanDerWaalsContact C-N 3.32Å; A212-S214 PolarHBondContact O-N 2.91Å; A212-H215 PolarHBondContact O-N 2.82Å; A212-Q216 WeakPolarHBondContact O-CA 3.25Å; A212-Q216 PolarHBondContact O-N 2.95Å; A212-R217 PolarHBondContact O-N 3.5Å; A212-F219 HydrophobicContact CB-CD2 3.57Å; A212-F219 HydrophobicContact CB-CE2 3.46Å; A212-F219 VanDerWaalsContact CB-CE2 3.46Å; A212-V273 HydrophobicContact CB-CB 4.24Å; A212-V273 HydrophobicContact CB-CG1 3.47Å; A212-V273 VanDerWaalsContact CB-CG1 3.47Å; A212-V273 HydrophobicContact CB-CG2 3.7Å; A212-V273 WeakPolarHBondContact O-CG2 3.44Å
213Q85.7Confident92.4Very high64 Ų6441.1 Ų41.130%0.29923%0.228SC..Hα-helixtrans-63.4-37.8179.4-78.4-177.4-4.700112.3Q209 T211 R272 V273 N479Q209-Q213 HydrophobicContact CG-CG 4.49Å; Q209-Q213 WeakPolarHBondContact O-CB 3.47Å; Q209-Q213 WeakPolarHBondContact O-CG 3.31Å; Q209-Q213 PolarHBondContact O-N 2.9Å; T211-Q213 PolarHBondContact O-N 3.25Å; Q213-R272 PolarHBondContact O-NE 3.23Å; Q213-R272 VanDerWaalsContact O-NE 3.07Å; Q213-R272 PolarHBondContact O-NH2 2.88Å; Q213-V273 HydrophobicContact CB-CG2 3.99Å; Q213-V273 HydrophobicContact CG-CG2 3.47Å; Q213-V273 VanDerWaalsContact CG-CG2 3.47Å; Q213-N479 PolarHBondContact NE2-ND2 3.37Å
214S87.9Confident92.5Very high86 Ų8636.8 Ų36.860%0.60121%0.208SC*.Hα-helixtrans-64.5-43.4178.1-64.20000112.3S210 T211 A212S210-S214 PolarHBondContact O-N 3.17Å; S210-S214 PolarHBondContact O-OG 3.2Å; T211-S214 PolarHBondContact O-N 2.93Å; A212-S214 VanDerWaalsContact C-N 3.32Å; A212-S214 PolarHBondContact O-N 2.91Å
215H86.9Confident92.4Very high106 Ų10635.7 Ų35.749%0.49120%0.199SC..Hα-helixtrans-100.64.6-174.2-66-67.9000115T211 A212 R217T211-H215 PolarHBondContact O-CD2 3.31Å; T211-H215 PolarHBondContact O-N 3.07Å; A212-H215 PolarHBondContact O-N 2.82Å; H215-R217 VanDerWaalsContact C-N 3.26Å; H215-R217 HydrophobicContact CB-CG 3.69Å; H215-R217 PolarHBondContact O-N 3.13Å
216Q87.3Confident92.3Very high104 Ų10440.6 Ų40.649%0.48622%0.217SC..THydrogen-bonded Turntrans54.839.2-173.9-55.1-173.729.500113.3A212 R267 R272A212-Q216 WeakPolarHBondContact O-CA 3.25Å; A212-Q216 PolarHBondContact O-N 2.95Å; Q216-R267 VanDerWaalsContact O-CZ 3.29Å; Q216-R267 PolarHBondContact O-NH1 2.8Å; Q216-R267 PolarHBondContact O-NH2 3.25Å; Q216-R272 CarbonylContact C-O 3.6Å; Q216-R272 WeakPolarHBondContact CA-O 3.16Å; Q216-R272 VanDerWaalsContact CG-CZ 3.48Å; Q216-R272 VanDerWaalsContact CG-NH2 3.27Å
217R91.9Very high92.2Very high56 Ų5644.5 Ų44.521%0.21123%0.234CC..  trans-90.1161.4-171.7-77176.3178.1154.16.3113.8A212 H215 F219 R267 N274 D306A212-R217 PolarHBondContact O-N 3.5Å; H215-R217 VanDerWaalsContact C-N 3.26Å; H215-R217 HydrophobicContact CB-CG 3.69Å; H215-R217 PolarHBondContact O-N 3.13Å; R217-F219 HydrophobicContact CB-CD2 4.15Å; R217-F219 HydrophobicContact CB-CE2 3.71Å; R217-R267 VanDerWaalsContact C-NH2 3.28Å; R217-R267 PolarHBondContact O-NH2 2.87Å; R217-N274 PolarHBondContact O-N 3.49Å; R217-D306 WeakPolarHBondContact CA-O 3.48Å; R217-D306 HydrophobicContact CG-CB 4.09Å; R217-D306 IonicContact CZ-OD2 3.55Å; R217-D306 IonicContact NE-OD2 2.74Å; R217-D306 PolarHBondContact NE-OD2 2.88Å; R217-D306 IonicContact NH2-OD2 3.56Å
218S94.9Very high92.4Very high0 Ų041.6 Ų41.60%021%0.21CC..EExtended strand (participates in β ladder)trans-105.7139.3166.9-59.90000109.7R267 N274 D306 T307 R308S218-R267 PolarHBondContact OG-NH2 2.86Å; S218-N274 CarbonylContact C-O 3.41Å; S218-N274 WeakPolarHBondContact CA-O 3.08Å; S218-N274 PolarHBondContact OG-OD1 3.01Å; S218-D306 PolarHBondContact N-O 3.43Å; S218-T307 VanDerWaalsContact O-CA 3.26Å; S218-T307 WeakPolarHBondContact O-CA 3.21Å; S218-R308 PolarHBondContact O-N 2.66Å
219F96.7Very high92.6Very high13 Ų1340.8 Ų40.86%0.05721%0.205CC..EExtended strand (participates in β ladder)trans-124.3132.9178.2-80.6-97.9000110.7V208 T211 A212 R217 V221 N274 I275 I276 R308V208-F219 HydrophobicContact CG1-CB 3.84Å; V208-F219 HydrophobicContact CG1-CD1 3.34Å; V208-F219 HydrophobicContact CG1-CD2 3.62Å; V208-F219 HydrophobicContact CG1-CE1 3.66Å; V208-F219 HydrophobicContact CG1-CE2 3.93Å; V208-F219 HydrophobicContact CG1-CG 3.31Å; V208-F219 HydrophobicContact CG1-CZ 3.94Å; T211-F219 HydrophobicContact CG2-CZ 4.06Å; A212-F219 HydrophobicContact CB-CD2 3.57Å; A212-F219 HydrophobicContact CB-CE2 3.46Å; A212-F219 VanDerWaalsContact CB-CE2 3.46Å; R217-F219 HydrophobicContact CB-CD2 4.15Å; R217-F219 HydrophobicContact CB-CE2 3.71Å; F219-V221 HydrophobicContact CB-CG2 4.47Å; F219-N274 PolarHBondContact N-O 2.72Å; F219-I275 HydrophobicContact CB-CD1 4Å; F219-I276 PolarHBondContact O-N 3.1Å; F219-R308 CarbonylContact C-O 3.58Å; F219-R308 WeakPolarHBondContact CA-O 3.1Å; F219-R308 HydrophobicContact CD1-CB 3.85Å; F219-R308 HydrophobicContact CE1-CB 3.66Å; F219-R308 HydrophobicContact CE1-CG 4.33Å; F219-R308 HydrophobicContact CZ-CB 4.21Å; F219-R308 HydrophobicContact CZ-CG 4.45Å
220V97.7Very high93Very high0 Ų041.3 Ų41.30%021%0.207CC..EExtended strand (participates in β ladder)trans-103.7109.5168.3-171.90000107.4I276 C278 A292 V295 R296 I299 T307 R308 I309 T310V220-I276 CarbonylContact C-O 3.55Å; V220-I276 WeakPolarHBondContact CA-O 3.39Å; V220-I276 HydrophobicContact CG2-CB 4.38Å; V220-C278 HydrophobicContact CG1-CB 4.38Å; V220-A292 HydrophobicContact CG1-CB 3.74Å; V220-V295 HydrophobicContact CG1-CB 4.2Å; V220-V295 HydrophobicContact CG1-CG1 4.09Å; V220-V295 HydrophobicContact CG2-CB 4.32Å; V220-V295 HydrophobicContact CG2-CG1 3.75Å; V220-R296 HydrophobicContact CG2-CB 4.43Å; V220-I299 HydrophobicContact CG2-CD1 4.3Å; V220-T307 HydrophobicContact CG2-CG2 3.98Å; V220-R308 PolarHBondContact N-O 3.24Å; V220-I309 HydrophobicContact CB-CG1 4.28Å; V220-I309 CarbonylContact O-C 3.54Å; V220-I309 VanDerWaalsContact O-CA 3.3Å; V220-I309 WeakPolarHBondContact O-CA 3.44Å; V220-T310 PolarHBondContact O-N 2.94Å
221V97.9Very high93.6Very high2 Ų237.9 Ų37.91%0.01218%0.183CC..EExtended strand (participates in β ladder)trans-100.6116.6-178-175.30000108.8I205 F219 V223 I276 I277 C278 T310 L312I205-V221 HydrophobicContact CG1-CG1 4.28Å; I205-V221 HydrophobicContact CG1-CG2 4.44Å; F219-V221 HydrophobicContact CB-CG2 4.47Å; V221-V223 HydrophobicContact CG1-CG1 4.21Å; V221-I276 PolarHBondContact N-O 2.78Å; V221-I277 WeakPolarHBondContact O-CA 3.45Å; V221-C278 PolarHBondContact O-N 3.22Å; V221-T310 WeakPolarHBondContact CA-O 3.3Å; V221-L312 HydrophobicContact CG1-CD1 4.02Å; V221-L312 HydrophobicContact CG1-CD2 4.18Å; V221-L312 HydrophobicContact CG1-CG 3.92Å
222E98.5Very high94Very high53 Ų5335.3 Ų35.325%0.24817%0.167CC..EExtended strand (participates in β ladder)trans-90125176.9-168.3-177.9115.400110.3C278 A292 T310 V311 L312E222-C278 WeakPolarHBondContact CA-O 3.28Å; E222-A292 HydrophobicContact CB-CB 4.31Å; E222-T310 PolarHBondContact N-O 3.41Å; E222-V311 HydrophobicContact CB-CB 4.38Å; E222-V311 HydrophobicContact CB-CG1 4.3Å; E222-V311 HydrophobicContact CB-CG2 4.05Å; E222-L312 PolarHBondContact O-N 3.42Å
223V98.3Very high94.5Very high2 Ų235.3 Ų35.31%0.01217%0.167CC..EExtended strand (participates in β ladder)trans-119.1147-175.8-59.30000111.2I201 V221 A232 I277 C278 E280 L312I201-V223 HydrophobicContact CD1-CB 4.27Å; I201-V223 HydrophobicContact CD1-CG1 4.3Å; I201-V223 HydrophobicContact CG1-CG1 4.28Å; I201-V223 HydrophobicContact CG2-CG1 3.87Å; V221-V223 HydrophobicContact CG1-CG1 4.21Å; V223-A232 HydrophobicContact CG2-CB 3.54Å; V223-I277 HydrophobicContact CG1-CG2 3.92Å; V223-I277 HydrophobicContact CG2-CG2 3.71Å; V223-C278 PolarHBondContact N-O 2.91Å; V223-E280 PolarHBondContact O-N 2.97Å; V223-L312 HydrophobicContact CG1-CD1 4.14Å
224M98.1Very high95Very high16 Ų1632.4 Ų32.48%0.07915%0.154CC..  trans-70.3169.7176.3-82.4-178.3154.300111.3I181 L231 Q316 R317I181-M224 HydrophobicContact CD1-CB 3.91Å; I181-M224 HydrophobicContact CD1-SD 3.94Å; M224-L231 WeakPolarHBondContact O-CD1 3.31Å; M224-Q316 HydrophobicContact SD-CB 4.39Å; M224-R317 HydrophobicContact SD-CG 4.33Å
225G95.1Very high95.5Very high1 Ų128.3 Ų28.31%0.0113%0.125CC..  trans154.1217600000113.6D182 H227 C228 E280D182-G225 VanDerWaalsContact OD1-CA 3.3Å; D182-G225 WeakPolarHBondContact OD1-CA 3.31Å; G225-H227 PolarHBondContact O-N 2.83Å; G225-C228 CarbonylContact C-O 3.59Å; G225-C228 WeakPolarHBondContact CA-O 3.14Å; G225-C228 WeakPolarHBondContact O-CA 3.38Å; G225-C228 WeakPolarHBondContact O-CB 3.4Å; G225-C228 PolarHBondContact O-N 2.79Å; G225-E280 PolarHBondContact N-OE1 2.86Å
226R92.8Very high95.9Very high103 Ų10323.4 Ų23.439%0.38910%0.103SC..THydrogen-bonded Turntrans55.7-98.1-173.5-173.5-167.7-70.9156.9-11.2111.4D135 D182 D184 E280 G281D135-R226 IonicContact OD1-NH1 3.3Å; D135-R226 PolarHBondContact OD1-NH1 2.83Å; D182-R226 IonicContact OD2-CZ 2.76Å; D184-R226 IonicContact OD2-NH1 2.73Å; D184-R226 PolarHBondContact OD2-NH1 2.82Å; D184-R226 VanDerWaalsContact OD2-NH1 3.13Å; R226-E280 VanDerWaalsContact CA-OE1 3.25Å; R226-E280 WeakPolarHBondContact CA-OE1 3.32Å; R226-E280 PolarHBondContact N-OE1 2.76Å; R226-G281 VanDerWaalsContact O-CA 3.22Å; R226-G281 WeakPolarHBondContact O-CA 3.49Å; R226-G281 PolarHBondContact O-N 3.05Å
227H92.7Very high96.1Very high114 Ų11418.7 Ų18.753%0.5288%0.081SC..THydrogen-bonded Turntrans-116.121.2176.5-57.4-54.7000110.9G225 M378 R390G225-H227 PolarHBondContact O-N 2.83Å; H227-M378 HydrophobicContact CB-CE 4.29Å; H227-M378 WeakPolarHBondContact O-CE 3.45Å; H227-R390 PolarHBondContact O-NH2 3.49Å
228C95.5Very high96.2Very high2 Ų216 Ų161%0.0147%0.071CC..  trans-119.4126.9176.4-168.50000111.2D184 G225 Y230 E248D184-C228 HydrophobicContact CB-CB 3.82Å; G225-C228 CarbonylContact C-O 3.59Å; G225-C228 WeakPolarHBondContact CA-O 3.14Å; G225-C228 WeakPolarHBondContact O-CA 3.38Å; G225-C228 WeakPolarHBondContact O-CB 3.4Å; G225-C228 PolarHBondContact O-N 2.79Å; C228-Y230 VanDerWaalsContact C-N 3.29Å; C228-Y230 PolarHBondContact O-N 2.85Å; C228-E248 VanDerWaalsContact CA-OE1 3.23Å; C228-E248 WeakPolarHBondContact CA-OE1 3.49Å; C228-E248 PolarHBondContact SG-OE1 3.25Å
229G96.7Very high96.1Very high0 Ų016.2 Ų16.20%07%0.073CC..  trans-85.17.5176.400000114.5L231 A232 L233 E248G229-L231 PolarHBondContact O-N 2.51Å; G229-A232 PolarHBondContact O-N 2.82Å; G229-L233 VanDerWaalsContact O-CB 3.27Å; G229-L233 WeakPolarHBondContact O-CB 3.36Å; G229-L233 PolarHBondContact O-N 2.85Å; G229-E248 VanDerWaalsContact CA-OE2 3.29Å; G229-E248 WeakPolarHBondContact CA-OE2 3.31Å; G229-E248 VanDerWaalsContact N-CD 3.34Å; G229-E248 PolarHBondContact N-OE1 3.07Å; G229-E248 PolarHBondContact N-OE2 3.49Å
230Y96.9Very high95.8Very high19 Ų1916.6 Ų16.68%0.0758%0.075CC..Hα-helixtrans-58.1-47.8-173.5-177.7-94.6000112.2N183 M190 T194 L198 C228 L233 V234 F394N183-Y230 HydrophobicContact CB-CD1 3.66Å; N183-Y230 HydrophobicContact CB-CE1 4.2Å; N183-Y230 HydrophobicContact CB-CG 3.95Å; N183-Y230 WeakPolarHBondContact ND2-CE1 3.42Å; M190-Y230 HydrophobicContact CE-CE1 4.41Å; M190-Y230 WeakPolarHBondContact CE-OH 3.5Å; M190-Y230 HydrophobicContact SD-CE1 4.03Å; T194-Y230 HydrophobicContact CG2-CD1 3.75Å; T194-Y230 HydrophobicContact CG2-CE1 3.59Å; L198-Y230 HydrophobicContact CD1-CE1 4.34Å; C228-Y230 VanDerWaalsContact C-N 3.29Å; C228-Y230 PolarHBondContact O-N 2.85Å; Y230-L233 PolarHBondContact O-N 2.96Å; Y230-V234 HydrophobicContact CD1-CG2 4.35Å; Y230-V234 HydrophobicContact CD2-CG2 4.3Å; Y230-V234 HydrophobicContact CE1-CG2 3.96Å; Y230-V234 HydrophobicContact CE2-CG2 3.92Å; Y230-V234 WeakPolarHBondContact O-CG2 3.22Å; Y230-V234 PolarHBondContact O-N 3.03Å; Y230-F394 AromaticContact CD2-CD2 3.99Å; Y230-F394 HydrophobicContact CD2-CD2 3.99Å
231L98Very high95.5Very high0 Ų016.7 Ų16.70%08%0.075CC..Hα-helixtrans-59.3-49.4177.4-71.3178.3000111.5I181 T194 A197 L198 I201 M224 G229 L233 A235I181-L231 HydrophobicContact CD1-CD1 4.37Å; I181-L231 HydrophobicContact CG1-CD1 4.4Å; T194-L231 HydrophobicContact CG2-CD2 3.93Å; A197-L231 HydrophobicContact CB-CD1 4.34Å; A197-L231 HydrophobicContact CB-CD2 4.07Å; L198-L231 HydrophobicContact CD2-CD2 3.71Å; L198-L231 HydrophobicContact CG-CD2 3.68Å; I201-L231 HydrophobicContact CD1-CB 3.9Å; I201-L231 HydrophobicContact CD1-CD1 4.28Å; I201-L231 HydrophobicContact CD1-CD2 4.17Å; I201-L231 HydrophobicContact CD1-CG 4.35Å; M224-L231 WeakPolarHBondContact O-CD1 3.31Å; G229-L231 PolarHBondContact O-N 2.51Å; L231-L233 PolarHBondContact O-N 2.85Å; L231-A235 WeakPolarHBondContact O-CB 3.41Å; L231-A235 PolarHBondContact O-N 3.2Å
232A98Very high95.2Very high0 Ų017.3 Ų17.30%08%0.078CC..Hα-helixtrans-60.8-44.4178.500000112.9V223 G229 G236 T244 I246 I277 A279V223-A232 HydrophobicContact CG2-CB 3.54Å; G229-A232 PolarHBondContact O-N 2.82Å; A232-G236 PolarHBondContact O-N 3.03Å; A232-T244 HydrophobicContact CB-CG2 3.93Å; A232-T244 WeakPolarHBondContact O-CG2 3.34Å; A232-I246 HydrophobicContact CB-CG2 3.82Å; A232-I277 HydrophobicContact CB-CG2 3.86Å; A232-A279 HydrophobicContact CB-CB 3.89Å
233L97.2Very high95.1Very high0 Ų015.6 Ų15.60%07%0.07CC..Hα-helixtrans-64.9-49.3-179.1174.459.9000111.7G229 Y230 L231 G236 L237 I246 F394 N397 L398 Y401G229-L233 VanDerWaalsContact O-CB 3.27Å; G229-L233 WeakPolarHBondContact O-CB 3.36Å; G229-L233 PolarHBondContact O-N 2.85Å; Y230-L233 PolarHBondContact O-N 2.96Å; L231-L233 PolarHBondContact O-N 2.85Å; L233-G236 PolarHBondContact O-N 2.84Å; L233-L237 PolarHBondContact O-N 2.78Å; L233-L237 VanDerWaalsContact O-N 3.1Å; L233-I246 HydrophobicContact CB-CG2 4.32Å; L233-F394 HydrophobicContact CD2-CD1 4.26Å; L233-F394 HydrophobicContact CD2-CD2 4.43Å; L233-F394 HydrophobicContact CD2-CE1 4.02Å; L233-F394 HydrophobicContact CD2-CE2 4.19Å; L233-F394 HydrophobicContact CD2-CG 4.45Å; L233-F394 HydrophobicContact CD2-CZ 3.97Å; L233-N397 HydrophobicContact CD2-CB 3.69Å; L233-N397 HydrophobicContact CG-CB 4Å; L233-L398 HydrophobicContact CD1-CD1 4.27Å; L233-L398 HydrophobicContact CD2-CB 4.13Å; L233-Y401 HydrophobicContact CD1-CD1 4.32Å; L233-Y401 HydrophobicContact CD1-CD2 4.41Å; L233-Y401 HydrophobicContact CD1-CG 3.88Å
234V96.5Very high95Very high4 Ų415.7 Ų15.72%0.0247%0.071CC..Hα-helixtrans-68.9-39.5179.9176.40000110.6L198 Y230 G236 L237 A238 N695L198-V234 HydrophobicContact CD1-CB 4.23Å; L198-V234 HydrophobicContact CD1-CG1 3.7Å; L198-V234 HydrophobicContact CD2-CB 3.91Å; L198-V234 HydrophobicContact CD2-CG1 3.94Å; L198-V234 HydrophobicContact CG-CG1 4.48Å; Y230-V234 HydrophobicContact CD1-CG2 4.35Å; Y230-V234 HydrophobicContact CD2-CG2 4.3Å; Y230-V234 HydrophobicContact CE1-CG2 3.96Å; Y230-V234 HydrophobicContact CE2-CG2 3.92Å; Y230-V234 WeakPolarHBondContact O-CG2 3.22Å; Y230-V234 PolarHBondContact O-N 3.03Å; V234-G236 VanDerWaalsContact C-N 3.35Å; V234-G236 PolarHBondContact O-N 3.03Å; V234-L237 PolarHBondContact O-N 3.44Å; V234-A238 WeakPolarHBondContact O-CB 3.44Å; V234-A238 PolarHBondContact O-N 2.97Å; V234-N695 HydrophobicContact CG1-CB 4.29Å
235A97.2Very high95Very high0 Ų015 Ų150%07%0.068CC..Hα-helixtrans-59.7-45.6173.100000111.3I201 I202 I205 L231 L237 A238 S239 I277I201-A235 HydrophobicContact CG2-CB 3.58Å; I202-A235 HydrophobicContact CD1-CB 4.36Å; I205-A235 HydrophobicContact CD1-CB 4.46Å; L231-A235 WeakPolarHBondContact O-CB 3.41Å; L231-A235 PolarHBondContact O-N 3.2Å; A235-L237 VanDerWaalsContact C-N 3.31Å; A235-L237 PolarHBondContact O-N 2.73Å; A235-A238 PolarHBondContact O-N 3.01Å; A235-A238 VanDerWaalsContact O-N 3.16Å; A235-S239 WeakPolarHBondContact O-CB 3.36Å; A235-S239 PolarHBondContact O-N 3.29Å; A235-S239 PolarHBondContact O-OG 3.11Å; A235-I277 HydrophobicContact CB-CD1 3.86Å
236G95.2Very high95.1Very high2 Ų215.1 Ų15.12%0.0217%0.068CC..Hα-helixtrans-61-37.8178.800000113.4A232 L233 V234 E240 A241A232-G236 PolarHBondContact O-N 3.03Å; L233-G236 PolarHBondContact O-N 2.84Å; V234-G236 VanDerWaalsContact C-N 3.35Å; V234-G236 PolarHBondContact O-N 3.03Å; G236-E240 PolarHBondContact O-N 3.5Å; G236-A241 PolarHBondContact O-N 3.18Å
237L93.1Very high95.3Very high6 Ų610.3 Ų10.33%0.0315%0.05CC..Hα-helixtrans-66.4-48.6171.8-78.4170.7000112.4L233 V234 A235 N397 T400 Y401 L404 N695L233-L237 PolarHBondContact O-N 2.78Å; L233-L237 VanDerWaalsContact O-N 3.1Å; V234-L237 PolarHBondContact O-N 3.44Å; A235-L237 VanDerWaalsContact C-N 3.31Å; A235-L237 PolarHBondContact O-N 2.73Å; L237-N397 HydrophobicContact CD1-CB 3.85Å; L237-N397 WeakPolarHBondContact CD1-OD1 3.46Å; L237-T400 HydrophobicContact CD2-CG2 3.99Å; L237-Y401 HydrophobicContact CD2-CD2 4.31Å; L237-Y401 HydrophobicContact CG-CD2 4.29Å; L237-L404 HydrophobicContact CD2-CD1 4.25Å; L237-N695 WeakPolarHBondContact CD1-ND2 3.1Å
238A93.7Very high95.4Very high0 Ų04.9 Ų4.90%03%0.025CC..Hα-helixtrans-71.7-30-174.500000112.9I202 V234 A235 S481 R694I202-A238 HydrophobicContact CD1-CB 3.74Å; I202-A238 HydrophobicContact CG1-CB 4.29Å; V234-A238 WeakPolarHBondContact O-CB 3.44Å; V234-A238 PolarHBondContact O-N 2.97Å; A235-A238 PolarHBondContact O-N 3.01Å; A235-A238 VanDerWaalsContact O-N 3.16Å; A238-S481 PolarHBondContact O-OG 2.98Å; A238-S481 VanDerWaalsContact O-OG 3.04Å; A238-R694 HydrophobicContact CB-CB 3.86Å; A238-R694 WeakPolarHBondContact O-CD 3.46Å
239S92.5Very high95.4Very high4 Ų49.4 Ų9.43%0.0284%0.041CC..THydrogen-bonded Turntrans-101.13.4-179.5800000114.6A235 A241A235-S239 WeakPolarHBondContact O-CB 3.36Å; A235-S239 PolarHBondContact O-N 3.29Å; A235-S239 PolarHBondContact O-OG 3.11Å; S239-A241 VanDerWaalsContact C-N 3.33Å; S239-A241 PolarHBondContact O-N 2.94Å
240E90.3Very high95.4Very high21 Ų2110 Ų1010%0.0985%0.045CC..THydrogen-bonded Turntrans59.437.5-177.1-42.4-173.1-167.500114.4G236 D242 R441 N479 W480 S481G236-E240 PolarHBondContact O-N 3.5Å; E240-D242 PolarHBondContact O-N 2.78Å; E240-R441 VanDerWaalsContact CD-CD 3.44Å; E240-R441 VanDerWaalsContact CG-CZ 3.48Å; E240-R441 VanDerWaalsContact CG-NH2 3.34Å; E240-R441 WeakPolarHBondContact OE1-CD 3.41Å; E240-R441 IonicContact OE1-CZ 3.38Å; E240-R441 IonicContact OE1-NE 3.68Å; E240-R441 PolarHBondContact OE1-NE 3.24Å; E240-R441 VanDerWaalsContact OE1-NE 3.09Å; E240-R441 IonicContact OE2-CZ 2.66Å; E240-R441 IonicContact OE2-NE 2.9Å; E240-R441 PolarHBondContact OE2-NE 3.11Å; E240-R441 IonicContact OE2-NH2 3.59Å; E240-R441 PolarHBondContact OE2-NH2 3.33Å; E240-N479 WeakPolarHBondContact OE1-CA 3.45Å; E240-N479 PolarHBondContact OE1-N 2.67Å; E240-N479 PolarHBondContact OE2-N 2.8Å; E240-W480 PolarHBondContact OE1-N 3.19Å; E240-S481 VanDerWaalsContact CG-OG 3.28Å; E240-S481 WeakPolarHBondContact CG-OG 3.24Å; E240-S481 WeakPolarHBondContact OE1-CB 3.38Å; E240-S481 PolarHBondContact OE1-N 2.6Å; E240-S481 PolarHBondContact OE1-OG 3.35Å; E240-S481 VanDerWaalsContact OE1-OG 3.05Å
241A92.3Very high95.3Very high2 Ų29.4 Ų9.42%0.0174%0.044CC..  trans-59.6135.2-17800000112.1G236 S239 F243 I275 I277G236-A241 PolarHBondContact O-N 3.18Å; S239-A241 VanDerWaalsContact C-N 3.33Å; S239-A241 PolarHBondContact O-N 2.94Å; A241-F243 VanDerWaalsContact C-N 3.29Å; A241-F243 PolarHBondContact O-N 2.97Å; A241-I275 HydrophobicContact CB-CG2 4.38Å; A241-I277 HydrophobicContact CB-CD1 3.82Å; A241-I277 HydrophobicContact CB-CG1 3.94Å
242D91.8Very high95Very high14 Ų1411.9 Ų11.98%0.0756%0.06CC..SBendtrans-64.8-36.1178.1-58.3-105.4000111.4E240 K262 L263 N274 I275E240-D242 PolarHBondContact O-N 2.78Å; D242-K262 WeakPolarHBondContact O-CD 3.43Å; D242-K262 WeakPolarHBondContact O-CE 3.28Å; D242-K262 PolarHBondContact O-NZ 3.48Å; D242-L263 HydrophobicContact CB-CD2 3.82Å; D242-N274 PolarHBondContact OD1-ND2 2.9Å; D242-N274 WeakPolarHBondContact OD2-CA 3.47Å; D242-I275 PolarHBondContact N-O 3.36Å; D242-I275 PolarHBondContact OD2-N 3.25Å
243F95.1Very high94.6Very high18 Ų1814.4 Ų14.48%0.0798%0.081CC..EExtended strand (participates in β ladder)trans-148.8146.1177.2-149.6-79.8000111.5A241 F245 I258 L259 K262 I276 I277 Y401A241-F243 VanDerWaalsContact C-N 3.29Å; A241-F243 PolarHBondContact O-N 2.97Å; F243-F245 HydrophobicContact CD1-CD1 4.41Å; F243-F245 AromaticContact CD1-CD2 3.94Å; F243-F245 HydrophobicContact CD1-CD2 3.94Å; F243-F245 HydrophobicContact CD1-CE1 4.1Å; F243-F245 AromaticContact CD1-CE2 3.58Å; F243-F245 HydrophobicContact CD1-CE2 3.58Å; F243-F245 HydrophobicContact CD1-CG 4.34Å; F243-F245 AromaticContact CD1-CZ 3.66Å; F243-F245 HydrophobicContact CD1-CZ 3.66Å; F243-F245 AromaticContact CE1-CD1 4Å; F243-F245 HydrophobicContact CE1-CD1 4Å; F243-F245 HydrophobicContact CE1-CD2 4.35Å; F243-F245 AromaticContact CE1-CE1 3.63Å; F243-F245 HydrophobicContact CE1-CE1 3.63Å; F243-F245 HydrophobicContact CE1-CE2 4.01Å; F243-F245 HydrophobicContact CE1-CG 4.34Å; F243-F245 AromaticContact CE1-CZ 3.63Å; F243-F245 HydrophobicContact CE1-CZ 3.63Å; F243-F245 HydrophobicContact CG-CE2 4.49Å; F243-I258 HydrophobicContact CE2-CG2 4.24Å; F243-L259 HydrophobicContact CB-CD1 3.72Å; F243-L259 HydrophobicContact CD1-CD1 4.39Å; F243-L259 HydrophobicContact CD2-CD1 3.91Å; F243-L259 HydrophobicContact CG-CD1 3.75Å; F243-K262 HydrophobicContact CD2-CD 3.74Å; F243-K262 HydrophobicContact CE2-CD 4.33Å; F243-I276 HydrophobicContact CB-CG1 4.41Å; F243-I276 HydrophobicContact CB-CG2 4.26Å; F243-I276 CarbonylContact O-C 3.55Å; F243-I276 WeakPolarHBondContact O-CA 3.4Å; F243-I277 PolarHBondContact O-N 3.26Å; F243-Y401 VanDerWaalsContact C-OH 3.24Å; F243-Y401 WeakPolarHBondContact CA-OH 3.47Å
244T96.8Very high94.4Very high4 Ų419.6 Ų19.63%0.02511%0.105CC..EExtended strand (participates in β ladder)trans-138.5121.7-179-54.30000108.8A232 I246 I277 Y401A232-T244 HydrophobicContact CB-CG2 3.93Å; A232-T244 WeakPolarHBondContact O-CG2 3.34Å; T244-I246 HydrophobicContact CG2-CG2 3.88Å; T244-I277 CarbonylContact C-O 3.58Å; T244-I277 VanDerWaalsContact CA-O 3.25Å; T244-I277 WeakPolarHBondContact CA-O 3.24Å; T244-I277 HydrophobicContact CG2-CB 4.14Å; T244-I277 HydrophobicContact CG2-CG2 4.28Å; T244-Y401 VanDerWaalsContact CB-OH 3.3Å; T244-Y401 WeakPolarHBondContact CB-OH 3.21Å; T244-Y401 PolarHBondContact N-OH 3.45Å; T244-Y401 VanDerWaalsContact OG1-CE2 3.3Å; T244-Y401 WeakPolarHBondContact OG1-CE2 3.25Å; T244-Y401 PolarHBondContact OG1-OH 3.01Å; T244-Y401 VanDerWaalsContact OG1-OH 3.11Å
245F97.7Very high94.3Very high2 Ų219.5 Ų19.51%0.00910%0.104CC..EExtended strand (participates in β ladder)trans-95118.2174.3-65.2-87.8000109.4F243 P251 W255 L259 I276 I277 A279 A282 I290 V295F243-F245 HydrophobicContact CD1-CD1 4.41Å; F243-F245 AromaticContact CD1-CD2 3.94Å; F243-F245 HydrophobicContact CD1-CD2 3.94Å; F243-F245 HydrophobicContact CD1-CE1 4.1Å; F243-F245 AromaticContact CD1-CE2 3.58Å; F243-F245 HydrophobicContact CD1-CE2 3.58Å; F243-F245 HydrophobicContact CD1-CG 4.34Å; F243-F245 AromaticContact CD1-CZ 3.66Å; F243-F245 HydrophobicContact CD1-CZ 3.66Å; F243-F245 AromaticContact CE1-CD1 4Å; F243-F245 HydrophobicContact CE1-CD1 4Å; F243-F245 HydrophobicContact CE1-CD2 4.35Å; F243-F245 AromaticContact CE1-CE1 3.63Å; F243-F245 HydrophobicContact CE1-CE1 3.63Å; F243-F245 HydrophobicContact CE1-CE2 4.01Å; F243-F245 HydrophobicContact CE1-CG 4.34Å; F243-F245 AromaticContact CE1-CZ 3.63Å; F243-F245 HydrophobicContact CE1-CZ 3.63Å; F243-F245 HydrophobicContact CG-CE2 4.49Å; F245-P251 HydrophobicContact CD1-CG 3.9Å; F245-P251 HydrophobicContact CE1-CG 3.87Å; F245-W255 HydrophobicContact CE1-CD2 4.07Å; F245-W255 AromaticContact CE1-CE3 3.63Å; F245-W255 HydrophobicContact CE1-CE3 3.63Å; F245-W255 AromaticContact CE1-CZ3 3.99Å; F245-W255 HydrophobicContact CE1-CZ3 3.99Å; F245-W255 HydrophobicContact CZ-CD2 4.42Å; F245-W255 AromaticContact CZ-CE3 3.53Å; F245-W255 HydrophobicContact CZ-CE3 3.53Å; F245-W255 AromaticContact CZ-CZ3 3.59Å; F245-W255 HydrophobicContact CZ-CZ3 3.59Å; F245-L259 HydrophobicContact CZ-CD2 4.3Å; F245-I276 HydrophobicContact CD2-CG2 3.99Å; F245-I276 HydrophobicContact CE2-CG2 3.74Å; F245-I277 PolarHBondContact N-O 3.36Å; F245-A279 WeakPolarHBondContact O-CB 3.17Å; F245-A279 PolarHBondContact O-N 2.94Å; F245-A282 HydrophobicContact CB-CB 3.81Å; F245-I290 HydrophobicContact CD1-CD1 3.75Å; F245-I290 HydrophobicContact CD1-CG2 4.12Å; F245-I290 HydrophobicContact CE1-CD1 4.01Å; F245-I290 HydrophobicContact CE1-CG2 4.29Å; F245-I290 HydrophobicContact CG-CG2 4.39Å; F245-V295 HydrophobicContact CD2-CG2 4.25Å; F245-V295 HydrophobicContact CE2-CG1 4.16Å; F245-V295 HydrophobicContact CE2-CG2 3.77Å; F245-V295 HydrophobicContact CZ-CG2 4.13Å
246I97.4Very high94.2Very high3 Ų323.5 Ų23.52%0.01512%0.119CC..BIsolated β-bridgetrans-127.7145.6176.661171.7000110.7A232 L233 T244 E248 W249 F394 L398A232-I246 HydrophobicContact CB-CG2 3.82Å; L233-I246 HydrophobicContact CB-CG2 4.32Å; T244-I246 HydrophobicContact CG2-CG2 3.88Å; I246-E248 VanDerWaalsContact C-N 3.35Å; I246-E248 PolarHBondContact O-N 2.93Å; I246-W249 HydrophobicContact CD1-CB 3.93Å; I246-W249 HydrophobicContact CG1-CB 3.95Å; I246-W249 CarbonylContact O-C 3.48Å; I246-W249 PolarHBondContact O-N 3.36Å; I246-F394 HydrophobicContact CD1-CE1 4.31Å; I246-F394 HydrophobicContact CD1-CZ 4.09Å; I246-L398 HydrophobicContact CD1-CD1 3.89Å
247P97Very high94.2Very high1 Ų127.5 Ų27.51%0.00614%0.14CC..THydrogen-bonded Turntrans-72.9-23.9-177.228.1-34.3000114.3W249 P250 G281 V283 M378P247-W249 VanDerWaalsContact C-N 3.33Å; P247-P250 WeakPolarHBondContact O-CD 3.41Å; P247-P250 WeakPolarHBondContact O-CG 3.46Å; P247-G281 WeakPolarHBondContact CB-O 3.47Å; P247-V283 HydrophobicContact CB-CG2 4.47Å; P247-M378 HydrophobicContact CB-CE 3.61Å; P247-M378 HydrophobicContact CG-CE 4.14Å
248E95.7Very high94.3Very high1 Ų130.2 Ų30.21%0.00515%0.154CC..THydrogen-bonded Turntrans-77.2-20.7178-6290.7162.800113.2C228 G229 I246 V387 R390 F394C228-E248 VanDerWaalsContact CA-OE1 3.23Å; C228-E248 WeakPolarHBondContact CA-OE1 3.49Å; C228-E248 PolarHBondContact SG-OE1 3.25Å; G229-E248 VanDerWaalsContact CA-OE2 3.29Å; G229-E248 WeakPolarHBondContact CA-OE2 3.31Å; G229-E248 VanDerWaalsContact N-CD 3.34Å; G229-E248 PolarHBondContact N-OE1 3.07Å; G229-E248 PolarHBondContact N-OE2 3.49Å; I246-E248 VanDerWaalsContact C-N 3.35Å; I246-E248 PolarHBondContact O-N 2.93Å; E248-V387 HydrophobicContact CB-CG2 3.85Å; E248-V387 WeakPolarHBondContact O-CG2 3.27Å; E248-R390 HydrophobicContact CG-CG 4.1Å; E248-R390 IonicContact OE1-CZ 2.65Å; E248-R390 IonicContact OE1-NE 2.93Å; E248-R390 PolarHBondContact OE1-NE 3.34Å; E248-R390 IonicContact OE1-NH2 3.81Å; E248-R390 PolarHBondContact OE1-NH2 3.18Å; E248-R390 VanDerWaalsContact OE1-NH2 3.13Å; E248-F394 HydrophobicContact CB-CE1 3.9Å; E248-F394 HydrophobicContact CB-CZ 3.87Å; E248-F394 HydrophobicContact CG-CE1 4.26Å; E248-F394 HydrophobicContact CG-CZ 3.89Å
249W95.3Very high94.3Very high96 Ų9630.2 Ų30.236%0.36415%0.154SC..BIsolated β-bridgetrans-132.473.6174.5-176.455.9000109.8I246 P247 L398 Y401 K402I246-W249 HydrophobicContact CD1-CB 3.93Å; I246-W249 HydrophobicContact CG1-CB 3.95Å; I246-W249 CarbonylContact O-C 3.48Å; I246-W249 PolarHBondContact O-N 3.36Å; P247-W249 VanDerWaalsContact C-N 3.33Å; W249-L398 HydrophobicContact CB-CD1 4.14Å; W249-L398 HydrophobicContact CB-CD2 3.95Å; W249-L398 HydrophobicContact CD2-CD1 4.06Å; W249-L398 HydrophobicContact CE3-CD1 3.83Å; W249-L398 HydrophobicContact CG-CD1 4.2Å; W249-L398 HydrophobicContact CG-CD2 4.17Å; W249-Y401 HydrophobicContact CZ3-CE1 4.32Å; W249-K402 HydrophobicContact CH2-CG 4.06Å; W249-K402 HydrophobicContact CZ2-CD 4.38Å; W249-K402 VanDerWaalsContact CZ2-CE 3.48Å; W249-K402 HydrophobicContact CZ2-CG 4.31Å; W249-K402 HydrophobicContact CZ3-CG 4.36Å
250P95.6Very high94.5Very high12 Ų1230.5 Ų30.58%0.07816%0.156CC..PPolyproline II helixtrans-61.3141.4178.8-24.737.7000111.1P247 V283 D284 W383P247-P250 WeakPolarHBondContact O-CD 3.41Å; P247-P250 WeakPolarHBondContact O-CG 3.46Å; P250-V283 HydrophobicContact CB-CG2 4.4Å; P250-V283 WeakPolarHBondContact CB-O 3.4Å; P250-V283 HydrophobicContact CG-CG2 3.93Å; P250-D284 WeakPolarHBondContact CB-O 3.48Å; P250-W383 HydrophobicContact CG-CD2 3.6Å; P250-W383 HydrophobicContact CG-CE3 3.68Å; P250-W383 HydrophobicContact CG-CG 4.23Å; P250-W383 HydrophobicContact CG-CH2 3.95Å; P250-W383 HydrophobicContact CG-CZ2 3.86Å; P250-W383 HydrophobicContact CG-CZ3 3.86Å
251P94.5Very high94.6Very high7 Ų735.1 Ų35.15%0.04518%0.178CC..PPolyproline II helixtrans-72.3160.2175.737.6-40.7000110.6F245 W255 V283 C285 I290F245-P251 HydrophobicContact CD1-CG 3.9Å; F245-P251 HydrophobicContact CE1-CG 3.87Å; P251-W255 HydrophobicContact CB-CB 3.57Å; P251-W255 HydrophobicContact CB-CG 4.42Å; P251-W255 HydrophobicContact CG-CB 3.7Å; P251-W255 HydrophobicContact CG-CG 4.02Å; P251-V283 WeakPolarHBondContact CD-O 3.24Å; P251-C285 WeakPolarHBondContact O-CB 3.41Å; P251-C285 PolarHBondContact O-N 2.83Å; P251-C285 VanDerWaalsContact O-N 3.11Å; P251-I290 HydrophobicContact CG-CD1 3.66Å
252P92.3Very high94.6Very high53 Ų5336.4 Ų36.434%0.34418%0.183SC..PPolyproline II helixtrans-66.1171.7177.730.2-36.9000112.1E254 W255 I258P252-E254 VanDerWaalsContact C-N 3.28Å; P252-E254 HydrophobicContact CG-CG 4.5Å; P252-E254 PolarHBondContact O-N 2.89Å; P252-W255 VanDerWaalsContact O-CB 3.28Å; P252-W255 WeakPolarHBondContact O-CB 3.4Å; P252-W255 PolarHBondContact O-N 3.31Å; P252-I258 HydrophobicContact CG-CD1 3.37Å
253A89.3Confident94.7Very high53 Ų5335.7 Ų35.744%0.43818%0.179SC..THydrogen-bonded Turntrans-57.6-39.6-177.300000112.7W255A253-W255 PolarHBondContact O-N 3.07Å; A253-W255 VanDerWaalsContact O-N 3.16Å
254E92.9Very high94.6Very high109 Ų10938.8 Ų38.851%0.50919%0.194SC..THydrogen-bonded Turntrans-77.421.1174.762.9-94.5-164.700114.9P252 R256 D257 I258P252-E254 VanDerWaalsContact C-N 3.28Å; P252-E254 HydrophobicContact CG-CG 4.5Å; P252-E254 PolarHBondContact O-N 2.89Å; E254-R256 PolarHBondContact O-N 2.91Å; E254-D257 PolarHBondContact O-N 2.88Å; E254-I258 HydrophobicContact CG-CD1 4.04Å; E254-I258 HydrophobicContact CG-CG1 4.29Å; E254-I258 PolarHBondContact O-N 2.97Å
255W94.9Very high94.2Very high1 Ų141.2 Ų41.20%0.00421%0.205CC..Hα-helixtrans-53.9-28.1-178.471.6-96.6000114.2F245 P251 P252 A253 I258 L259 I290 V295 I298F245-W255 HydrophobicContact CE1-CD2 4.07Å; F245-W255 AromaticContact CE1-CE3 3.63Å; F245-W255 HydrophobicContact CE1-CE3 3.63Å; F245-W255 AromaticContact CE1-CZ3 3.99Å; F245-W255 HydrophobicContact CE1-CZ3 3.99Å; F245-W255 HydrophobicContact CZ-CD2 4.42Å; F245-W255 AromaticContact CZ-CE3 3.53Å; F245-W255 HydrophobicContact CZ-CE3 3.53Å; F245-W255 AromaticContact CZ-CZ3 3.59Å; F245-W255 HydrophobicContact CZ-CZ3 3.59Å; P251-W255 HydrophobicContact CB-CB 3.57Å; P251-W255 HydrophobicContact CB-CG 4.42Å; P251-W255 HydrophobicContact CG-CB 3.7Å; P251-W255 HydrophobicContact CG-CG 4.02Å; P252-W255 VanDerWaalsContact O-CB 3.28Å; P252-W255 WeakPolarHBondContact O-CB 3.4Å; P252-W255 PolarHBondContact O-N 3.31Å; A253-W255 PolarHBondContact O-N 3.07Å; A253-W255 VanDerWaalsContact O-N 3.16Å; W255-I258 PolarHBondContact O-N 2.88Å; W255-L259 HydrophobicContact CE3-CB 4.43Å; W255-L259 HydrophobicContact CE3-CD2 4.35Å; W255-L259 HydrophobicContact CZ3-CD2 3.9Å; W255-L259 VanDerWaalsContact O-CB 3.23Å; W255-L259 WeakPolarHBondContact O-CB 3.46Å; W255-L259 PolarHBondContact O-N 2.9Å; W255-I290 HydrophobicContact CH2-CG2 4.07Å; W255-I290 HydrophobicContact CZ2-CG1 4.42Å; W255-I290 HydrophobicContact CZ2-CG2 4.09Å; W255-V295 HydrophobicContact CH2-CG2 3.87Å; W255-V295 HydrophobicContact CZ3-CG2 4.01Å; W255-I298 HydrophobicContact CH2-CD1 3.2Å; W255-I298 HydrophobicContact CZ2-CD1 3.7Å; W255-I298 HydrophobicContact CZ3-CD1 3.8Å
256R95.9Very high93.7Very high84 Ų8442.1 Ų42.132%0.31721%0.21SC..Hα-helixtrans-63.4-45177.8-53.5-170.2171.169.1-1.2111.2E254 C260 I298E254-R256 PolarHBondContact O-N 2.91Å; R256-C260 WeakPolarHBondContact O-CB 3.35Å; R256-C260 PolarHBondContact O-N 3.26Å; R256-C260 PolarHBondContact O-SG 2.94Å; R256-I298 HydrophobicContact CB-CD1 4.4Å; R256-I298 HydrophobicContact CB-CG2 4.13Å; R256-I298 HydrophobicContact CG-CD1 3.7Å; R256-I298 HydrophobicContact CG-CG1 4.46Å
257D95.4Very high93.2Very high86 Ų8643.7 Ų43.746%0.4622%0.216SC..Hα-helixtrans-68.3-45.6178.2-60.3-57.6000110.4E254 L259 C260 Q261 R302E254-D257 PolarHBondContact O-N 2.88Å; D257-L259 PolarHBondContact O-N 3.35Å; D257-C260 PolarHBondContact O-N 3.4Å; D257-Q261 WeakPolarHBondContact O-CB 3.5Å; D257-Q261 PolarHBondContact O-N 3.34Å; D257-R302 IonicContact OD1-CZ 3.57Å; D257-R302 IonicContact OD1-NH1 3.27Å; D257-R302 PolarHBondContact OD1-NH1 3.31Å; D257-R302 IonicContact OD1-NH2 2.78Å; D257-R302 IonicContact OD2-NH1 3.66Å
258I93.6Very high92.7Very high63 Ų6349.4 Ų49.432%0.32325%0.246SC..Hα-helixtrans-59.1-46.9177.9-62.3174.4000110.9F243 P252 E254 W255 K262F243-I258 HydrophobicContact CE2-CG2 4.24Å; P252-I258 HydrophobicContact CG-CD1 3.37Å; E254-I258 HydrophobicContact CG-CD1 4.04Å; E254-I258 HydrophobicContact CG-CG1 4.29Å; E254-I258 PolarHBondContact O-N 2.97Å; W255-I258 PolarHBondContact O-N 2.88Å; I258-K262 VanDerWaalsContact O-CB 3.23Å; I258-K262 WeakPolarHBondContact O-CB 3.23Å; I258-K262 PolarHBondContact O-N 3.26Å
259L95.2Very high92Very high0 Ų051.9 Ų51.90%026%0.258CS..Hα-helixtrans-60.2-52.6177.4176.368.4000110.2F243 F245 W255 D257 Q261 K262 L263 I276 V295 I299F243-L259 HydrophobicContact CB-CD1 3.72Å; F243-L259 HydrophobicContact CD1-CD1 4.39Å; F243-L259 HydrophobicContact CD2-CD1 3.91Å; F243-L259 HydrophobicContact CG-CD1 3.75Å; F245-L259 HydrophobicContact CZ-CD2 4.3Å; W255-L259 HydrophobicContact CE3-CB 4.43Å; W255-L259 HydrophobicContact CE3-CD2 4.35Å; W255-L259 HydrophobicContact CZ3-CD2 3.9Å; W255-L259 VanDerWaalsContact O-CB 3.23Å; W255-L259 WeakPolarHBondContact O-CB 3.46Å; W255-L259 PolarHBondContact O-N 2.9Å; D257-L259 PolarHBondContact O-N 3.35Å; L259-Q261 PolarHBondContact O-N 3.21Å; L259-K262 PolarHBondContact O-N 3.02Å; L259-K262 VanDerWaalsContact O-N 3.15Å; L259-L263 HydrophobicContact CD1-CD1 3.91Å; L259-L263 HydrophobicContact CD1-CD2 4.28Å; L259-L263 HydrophobicContact CD1-CG 3.92Å; L259-L263 HydrophobicContact CG-CD1 4.05Å; L259-L263 HydrophobicContact CG-CG 4.29Å; L259-L263 VanDerWaalsContact O-CG 3.32Å; L259-L263 WeakPolarHBondContact O-CG 3.47Å; L259-L263 PolarHBondContact O-N 2.94Å; L259-I276 HydrophobicContact CD1-CG1 4.32Å; L259-V295 HydrophobicContact CD2-CG1 3.88Å; L259-I299 HydrophobicContact CD2-CD1 4.26Å; L259-I299 HydrophobicContact CD2-CG1 4.11Å
260C95.3Very high91.3Very high11 Ų1150 Ų507%0.07427%0.269CS..Hα-helixtrans-60.8-45.8-176.7-750000112.3R256 D257 K262 L263 H264 L303R256-C260 WeakPolarHBondContact O-CB 3.35Å; R256-C260 PolarHBondContact O-N 3.26Å; R256-C260 PolarHBondContact O-SG 2.94Å; D257-C260 PolarHBondContact O-N 3.4Å; C260-K262 VanDerWaalsContact C-N 3.3Å; C260-K262 PolarHBondContact O-N 2.77Å; C260-L263 PolarHBondContact O-N 3.18Å; C260-H264 VanDerWaalsContact O-CB 3.27Å; C260-H264 WeakPolarHBondContact O-CB 3.32Å; C260-H264 PolarHBondContact O-N 3.26Å; C260-L303 HydrophobicContact CB-CD1 4.27Å; C260-L303 HydrophobicContact CB-CD2 4.08Å; C260-L303 HydrophobicContact CB-CG 4.17Å
261Q93.7Very high90.7Very high118 Ų11851 Ų5155%0.55127%0.272SS*.Hα-helixtrans-57.3-47.5175.1-179.1-179.50.800110.4D257 L259 L263 H264 E265D257-Q261 WeakPolarHBondContact O-CB 3.5Å; D257-Q261 PolarHBondContact O-N 3.34Å; L259-Q261 PolarHBondContact O-N 3.21Å; Q261-L263 PolarHBondContact O-N 3.17Å; Q261-H264 PolarHBondContact O-N 3.39Å; Q261-E265 HydrophobicContact CG-CG 4.4Å; Q261-E265 VanDerWaalsContact CG-OE1 3.29Å; Q261-E265 WeakPolarHBondContact CG-OE1 3.25Å; Q261-E265 PolarHBondContact NE2-OE1 3.47Å; Q261-E265 WeakPolarHBondContact O-CB 3.27Å; Q261-E265 WeakPolarHBondContact O-CG 3.19Å; Q261-E265 PolarHBondContact O-N 3.13Å
262K91.5Very high90.3Very high28 Ų2855.9 Ų55.912%0.12229%0.29CS..Hα-helixtrans-63.1-46.3-177.1-164.1-173.4-165.7179.50112.3D242 F243 I258 L259 C260 E265 T266 T405 I407D242-K262 WeakPolarHBondContact O-CD 3.43Å; D242-K262 WeakPolarHBondContact O-CE 3.28Å; D242-K262 PolarHBondContact O-NZ 3.48Å; F243-K262 HydrophobicContact CD2-CD 3.74Å; F243-K262 HydrophobicContact CE2-CD 4.33Å; I258-K262 VanDerWaalsContact O-CB 3.23Å; I258-K262 WeakPolarHBondContact O-CB 3.23Å; I258-K262 PolarHBondContact O-N 3.26Å; L259-K262 PolarHBondContact O-N 3.02Å; L259-K262 VanDerWaalsContact O-N 3.15Å; C260-K262 VanDerWaalsContact C-N 3.3Å; C260-K262 PolarHBondContact O-N 2.77Å; K262-E265 PolarHBondContact O-N 3.19Å; K262-T266 WeakPolarHBondContact O-CG2 3.48Å; K262-T266 PolarHBondContact O-N 3.22Å; K262-T266 PolarHBondContact O-OG1 2.65Å; K262-T266 VanDerWaalsContact O-OG1 3.1Å; K262-T405 WeakPolarHBondContact CE-O 3.31Å; K262-T405 VanDerWaalsContact NZ-CB 3.3Å; K262-T405 PolarHBondContact NZ-O 3.41Å; K262-T405 PolarHBondContact NZ-OG1 2.97Å; K262-I407 HydrophobicContact CB-CD1 4.02Å; K262-I407 HydrophobicContact CG-CD1 3.42Å; K262-I407 VanDerWaalsContact CG-CD1 3.42Å; K262-I407 HydrophobicContact CG-CG1 3.88Å
263L93.3Very high90.2Very high0 Ų053.6 Ų53.60%027%0.274CS..Hα-helixtrans-66.7-38.2178.8-62.8-172.2000111.9D242 L259 C260 Q261 T266 R267 N274 I276 I299 L303 Y305D242-L263 HydrophobicContact CB-CD2 3.82Å; L259-L263 HydrophobicContact CD1-CD1 3.91Å; L259-L263 HydrophobicContact CD1-CD2 4.28Å; L259-L263 HydrophobicContact CD1-CG 3.92Å; L259-L263 HydrophobicContact CG-CD1 4.05Å; L259-L263 HydrophobicContact CG-CG 4.29Å; L259-L263 VanDerWaalsContact O-CG 3.32Å; L259-L263 WeakPolarHBondContact O-CG 3.47Å; L259-L263 PolarHBondContact O-N 2.94Å; C260-L263 PolarHBondContact O-N 3.18Å; Q261-L263 PolarHBondContact O-N 3.17Å; L263-T266 WeakPolarHBondContact CA-OG1 3.45Å; L263-T266 PolarHBondContact O-OG1 3.32Å; L263-R267 WeakPolarHBondContact O-CB 3.31Å; L263-R267 WeakPolarHBondContact O-CG 3.44Å; L263-R267 PolarHBondContact O-N 2.89Å; L263-N274 HydrophobicContact CD2-CB 3.83Å; L263-I276 HydrophobicContact CD1-CD1 4.02Å; L263-I276 HydrophobicContact CD1-CG1 4.39Å; L263-I276 HydrophobicContact CD2-CD1 4.3Å; L263-I276 HydrophobicContact CD2-CG1 4.4Å; L263-I299 HydrophobicContact CD1-CD1 3.62Å; L263-I299 HydrophobicContact CD1-CG1 3.77Å; L263-I299 HydrophobicContact CD1-CG2 4.37Å; L263-L303 HydrophobicContact CB-CD1 3.78Å; L263-L303 HydrophobicContact CD1-CD1 4.41Å; L263-Y305 HydrophobicContact CB-CE2 4.5Å
264H92.9Very high90.3Very high83 Ų8351 Ų5138%0.38425%0.254SS..Hα-helixtrans-64.7-47.2176.4-172.564.6000111.7C260 Q261 R267 L268 L303 Y305C260-H264 VanDerWaalsContact O-CB 3.27Å; C260-H264 WeakPolarHBondContact O-CB 3.32Å; C260-H264 PolarHBondContact O-N 3.26Å; Q261-H264 PolarHBondContact O-N 3.39Å; H264-R267 WeakPolarHBondContact O-CB 3.33Å; H264-R267 PolarHBondContact O-N 2.85Å; H264-L268 WeakPolarHBondContact O-CG 3.14Å; H264-L268 PolarHBondContact O-N 2.93Å; H264-L303 HydrophobicContact CB-CD2 4.03Å; H264-Y305 PolarHBondContact ND1-OH 3.1Å
265E88.8Confident90.4Very high55 Ų5546.1 Ų46.126%0.25723%0.231SC..Hα-helixtrans-62.9-45.6178.7-75.5-179.3-161.900111.6Q261 K262 R267 L268 H269 I407Q261-E265 HydrophobicContact CG-CG 4.4Å; Q261-E265 VanDerWaalsContact CG-OE1 3.29Å; Q261-E265 WeakPolarHBondContact CG-OE1 3.25Å; Q261-E265 PolarHBondContact NE2-OE1 3.47Å; Q261-E265 WeakPolarHBondContact O-CB 3.27Å; Q261-E265 WeakPolarHBondContact O-CG 3.19Å; Q261-E265 PolarHBondContact O-N 3.13Å; K262-E265 PolarHBondContact O-N 3.19Å; E265-R267 VanDerWaalsContact C-N 3.25Å; E265-R267 PolarHBondContact O-N 3.03Å; E265-L268 WeakPolarHBondContact O-CB 3.36Å; E265-L268 PolarHBondContact O-N 3.29Å; E265-L268 VanDerWaalsContact O-N 3.16Å; E265-H269 PolarHBondContact O-N 3.26Å; E265-H269 PolarHBondContact O-ND1 3.31Å; E265-I407 HydrophobicContact CB-CD1 3.61Å; E265-I407 HydrophobicContact CB-CG2 4.14Å; E265-I407 HydrophobicContact CG-CD1 4.4Å; E265-I407 VanDerWaalsContact OE2-CD1 3.25Å; E265-I407 WeakPolarHBondContact OE2-CD1 3.48Å
266T86.5Confident90.5Very high20 Ų2046 Ų4612%0.12323%0.23CC..Hα-helixtrans-56.5-40.8176.749.80000112.1K262 L263 H269 Q271 N274 I407K262-T266 WeakPolarHBondContact O-CG2 3.48Å; K262-T266 PolarHBondContact O-N 3.22Å; K262-T266 PolarHBondContact O-OG1 2.65Å; K262-T266 VanDerWaalsContact O-OG1 3.1Å; L263-T266 WeakPolarHBondContact CA-OG1 3.45Å; L263-T266 PolarHBondContact O-OG1 3.32Å; T266-H269 PolarHBondContact O-N 2.88Å; T266-Q271 WeakPolarHBondContact O-CB 3.35Å; T266-Q271 PolarHBondContact O-N 2.97Å; T266-N274 PolarHBondContact OG1-ND2 3.15Å; T266-I407 HydrophobicContact CG2-CD1 4.4Å; T266-I407 HydrophobicContact CG2-CG1 4.02Å; T266-I407 HydrophobicContact CG2-CG2 4.48Å
267R87.5Confident90.6Very high36 Ų3642 Ų4214%0.13622%0.215CC..Hα-helixtrans-65-42.3176.6-71.8-88.6174.5160.710.9113.1Q216 R217 S218 L263 H264 E265 H269 G270 Q271 R272 N274 Y305Q216-R267 VanDerWaalsContact O-CZ 3.29Å; Q216-R267 PolarHBondContact O-NH1 2.8Å; Q216-R267 PolarHBondContact O-NH2 3.25Å; R217-R267 VanDerWaalsContact C-NH2 3.28Å; R217-R267 PolarHBondContact O-NH2 2.87Å; S218-R267 PolarHBondContact OG-NH2 2.86Å; L263-R267 WeakPolarHBondContact O-CB 3.31Å; L263-R267 WeakPolarHBondContact O-CG 3.44Å; L263-R267 PolarHBondContact O-N 2.89Å; H264-R267 WeakPolarHBondContact O-CB 3.33Å; H264-R267 PolarHBondContact O-N 2.85Å; E265-R267 VanDerWaalsContact C-N 3.25Å; E265-R267 PolarHBondContact O-N 3.03Å; R267-H269 PolarHBondContact O-N 3.43Å; R267-G270 PolarHBondContact O-N 3.38Å; R267-Q271 VanDerWaalsContact CD-O 3.25Å; R267-Q271 WeakPolarHBondContact CD-O 3.24Å; R267-R272 PolarHBondContact NH1-O 3.19Å; R267-R272 PolarHBondContact NH2-O 3.5Å; R267-N274 PolarHBondContact NE-OD1 3.49Å; R267-N274 PolarHBondContact NH2-OD1 2.91Å; R267-Y305 HydrophobicContact CB-CE2 4.49Å; R267-Y305 HydrophobicContact CG-CE2 3.68Å
268L87.1Confident90.8Very high122 Ų12238 Ų3864%0.63919%0.194SC*.Hα-helixtrans-59.4-29.5175.7-73.4175.1000112.3H264 E265 G270H264-L268 WeakPolarHBondContact O-CG 3.14Å; H264-L268 PolarHBondContact O-N 2.93Å; E265-L268 WeakPolarHBondContact O-CB 3.36Å; E265-L268 PolarHBondContact O-N 3.29Å; E265-L268 VanDerWaalsContact O-N 3.16Å; L268-G270 VanDerWaalsContact C-N 3.27Å; L268-G270 PolarHBondContact O-N 3.13Å
269H80.6Confident91Very high52 Ų5235.1 Ų35.124%0.24118%0.179CC..THydrogen-bonded Turntrans-90.418.3176.6-58.282.3000113.8E265 T266 R267 R408 H475E265-H269 PolarHBondContact O-N 3.26Å; E265-H269 PolarHBondContact O-ND1 3.31Å; T266-H269 PolarHBondContact O-N 2.88Å; R267-H269 PolarHBondContact O-N 3.43Å; H269-R408 PolarHBondContact CE1-NE 2.8Å; H269-R408 PolarHBondContact CE1-NH2 3.4Å; H269-R408 VanDerWaalsContact NE2-CZ 3.33Å; H269-R408 PolarHBondContact NE2-NE 2.82Å; H269-R408 PolarHBondContact NE2-NH2 2.85Å; H269-H475 WeakPolarHBondContact CB-NE2 3.41Å; H269-H475 AromaticContact CD2-CE1 3.89Å; H269-H475 AromaticContact CG-NE2 3.85Å; H269-H475 PolarHBondContact O-CD2 2.73Å
270G81Confident91Very high58 Ų5838.9 Ų38.960%0.59820%0.197SC*.THydrogen-bonded Turntrans90.21.8171.200000115.3R267 L268 R272R267-G270 PolarHBondContact O-N 3.38Å; L268-G270 VanDerWaalsContact C-N 3.27Å; L268-G270 PolarHBondContact O-N 3.13Å; G270-R272 PolarHBondContact O-N 3.34Å; G270-R272 VanDerWaalsContact O-N 3.14Å
271Q83.3Confident91.1Very high31 Ų3139 Ų3915%0.14520%0.201CC..  trans-62.8117.2171.9-170.279.5-8.400109.1T266 R267 V273T266-Q271 WeakPolarHBondContact O-CB 3.35Å; T266-Q271 PolarHBondContact O-N 2.97Å; R267-Q271 VanDerWaalsContact CD-O 3.25Å; R267-Q271 WeakPolarHBondContact CD-O 3.24Å; Q271-V273 WeakPolarHBondContact CG-O 3.35Å; Q271-V273 PolarHBondContact NE2-O 2.83Å
272R85.6Confident91.3Very high111 Ų11133.6 Ų33.642%0.41918%0.175SC..  trans-81.1-16.7-179.8-66.6178.359.678.9-1113.8Q213 Q216 R267 G270Q213-R272 PolarHBondContact O-NE 3.23Å; Q213-R272 VanDerWaalsContact O-NE 3.07Å; Q213-R272 PolarHBondContact O-NH2 2.88Å; Q216-R272 CarbonylContact C-O 3.6Å; Q216-R272 WeakPolarHBondContact CA-O 3.16Å; Q216-R272 VanDerWaalsContact CG-CZ 3.48Å; Q216-R272 VanDerWaalsContact CG-NH2 3.27Å; R267-R272 PolarHBondContact NH1-O 3.19Å; R267-R272 PolarHBondContact NH2-O 3.5Å; G270-R272 PolarHBondContact O-N 3.34Å; G270-R272 VanDerWaalsContact O-N 3.14Å
273V89.9Confident91.5Very high4 Ų433.5 Ų33.52%0.02418%0.177CC..  trans-135.2138.6-170.3176.10000109.4A212 Q213 Q271 I275A212-V273 HydrophobicContact CB-CB 4.24Å; A212-V273 HydrophobicContact CB-CG1 3.47Å; A212-V273 VanDerWaalsContact CB-CG1 3.47Å; A212-V273 HydrophobicContact CB-CG2 3.7Å; A212-V273 WeakPolarHBondContact O-CG2 3.44Å; Q213-V273 HydrophobicContact CB-CG2 3.99Å; Q213-V273 HydrophobicContact CG-CG2 3.47Å; Q213-V273 VanDerWaalsContact CG-CG2 3.47Å; Q271-V273 WeakPolarHBondContact CG-O 3.35Å; Q271-V273 PolarHBondContact NE2-O 2.83Å; V273-I275 HydrophobicContact CG1-CD1 3.69Å; V273-I275 HydrophobicContact CG1-CG1 3.97Å
274N92.5Very high91.6Very high0 Ų034.2 Ų34.20%018%0.181CC..EExtended strand (participates in β ladder)trans-114.3129.5164.5-57.6114.6000110.5R217 S218 F219 D242 L263 T266 R267 I276R217-N274 PolarHBondContact O-N 3.49Å; S218-N274 CarbonylContact C-O 3.41Å; S218-N274 WeakPolarHBondContact CA-O 3.08Å; S218-N274 PolarHBondContact OG-OD1 3.01Å; F219-N274 PolarHBondContact N-O 2.72Å; D242-N274 PolarHBondContact OD1-ND2 2.9Å; D242-N274 WeakPolarHBondContact OD2-CA 3.47Å; L263-N274 HydrophobicContact CD2-CB 3.83Å; T266-N274 PolarHBondContact OG1-ND2 3.15Å; R267-N274 PolarHBondContact NE-OD1 3.49Å; R267-N274 PolarHBondContact NH2-OD1 2.91Å; N274-I276 HydrophobicContact CB-CD1 4.11Å
275I94.4Very high91.6Very high5 Ų532.1 Ų32.13%0.02618%0.175CC..EExtended strand (participates in β ladder)trans-111.7119.1172.1-57.2-57.9000108.2I205 V208 F219 A241 D242 V273 I277I205-I275 HydrophobicContact CG2-CG2 4.21Å; V208-I275 HydrophobicContact CG1-CD1 4.36Å; F219-I275 HydrophobicContact CB-CD1 4Å; A241-I275 HydrophobicContact CB-CG2 4.38Å; D242-I275 PolarHBondContact N-O 3.36Å; D242-I275 PolarHBondContact OD2-N 3.25Å; V273-I275 HydrophobicContact CG1-CD1 3.69Å; V273-I275 HydrophobicContact CG1-CG1 3.97Å; I275-I277 HydrophobicContact CG2-CG1 4.26Å
276I97.2Very high91.7Very high0 Ų033.9 Ų33.90%019%0.186CC..EExtended strand (participates in β ladder)trans-111.6126.7174.2-57.387.1000107.3F219 V220 V221 F243 F245 L259 L263 N274 V295 I299F219-I276 PolarHBondContact O-N 3.1Å; V220-I276 CarbonylContact C-O 3.55Å; V220-I276 WeakPolarHBondContact CA-O 3.39Å; V220-I276 HydrophobicContact CG2-CB 4.38Å; V221-I276 PolarHBondContact N-O 2.78Å; F243-I276 HydrophobicContact CB-CG1 4.41Å; F243-I276 HydrophobicContact CB-CG2 4.26Å; F243-I276 CarbonylContact O-C 3.55Å; F243-I276 WeakPolarHBondContact O-CA 3.4Å; F245-I276 HydrophobicContact CD2-CG2 3.99Å; F245-I276 HydrophobicContact CE2-CG2 3.74Å; L259-I276 HydrophobicContact CD1-CG1 4.32Å; L263-I276 HydrophobicContact CD1-CD1 4.02Å; L263-I276 HydrophobicContact CD1-CG1 4.39Å; L263-I276 HydrophobicContact CD2-CD1 4.3Å; L263-I276 HydrophobicContact CD2-CG1 4.4Å; N274-I276 HydrophobicContact CB-CD1 4.11Å; I276-V295 HydrophobicContact CG2-CG1 4Å; I276-I299 HydrophobicContact CD1-CD1 3.86Å; I276-I299 HydrophobicContact CG1-CD1 4.35Å
277I98Very high91.9Very high0 Ų034.5 Ų34.50%020%0.197CC..EExtended strand (participates in β ladder)trans-105127.2176.5-61179.3000108.8I205 V221 V223 A232 A235 A241 F243 T244 F245 I275I205-I277 HydrophobicContact CD1-CD1 3.67Å; I205-I277 HydrophobicContact CD1-CG1 4.27Å; V221-I277 WeakPolarHBondContact O-CA 3.45Å; V223-I277 HydrophobicContact CG1-CG2 3.92Å; V223-I277 HydrophobicContact CG2-CG2 3.71Å; A232-I277 HydrophobicContact CB-CG2 3.86Å; A235-I277 HydrophobicContact CB-CD1 3.86Å; A241-I277 HydrophobicContact CB-CD1 3.82Å; A241-I277 HydrophobicContact CB-CG1 3.94Å; F243-I277 PolarHBondContact O-N 3.26Å; T244-I277 CarbonylContact C-O 3.58Å; T244-I277 VanDerWaalsContact CA-O 3.25Å; T244-I277 WeakPolarHBondContact CA-O 3.24Å; T244-I277 HydrophobicContact CG2-CB 4.14Å; T244-I277 HydrophobicContact CG2-CG2 4.28Å; F245-I277 PolarHBondContact N-O 3.36Å; I275-I277 HydrophobicContact CG2-CG1 4.26Å
278C98.1Very high92.2Very high1 Ų135.4 Ų35.41%0.00721%0.209CC..EExtended strand (participates in β ladder)trans-116.1117.1176.8-164.30000109.3V220 V221 E222 V223V220-C278 HydrophobicContact CG1-CB 4.38Å; V221-C278 PolarHBondContact O-N 3.22Å; E222-C278 WeakPolarHBondContact CA-O 3.28Å; V223-C278 PolarHBondContact N-O 2.91Å
279A98.3Very high92.7Very high2 Ų234 Ų342%0.01721%0.207CC..EExtended strand (participates in β ladder)trans-64.6143.216800000109.9A232 F245 G281 A282A232-A279 HydrophobicContact CB-CB 3.89Å; F245-A279 WeakPolarHBondContact O-CB 3.17Å; F245-A279 PolarHBondContact O-N 2.94Å; A279-G281 PolarHBondContact O-N 2.59Å; A279-G281 VanDerWaalsContact O-N 3.13Å; A279-A282 WeakPolarHBondContact O-CB 3.39Å; A279-A282 PolarHBondContact O-N 2.85Å
280E96.7Very high93.5Very high79 Ų7931.8 Ų31.837%0.36920%0.197SC..THydrogen-bonded Turntrans-59.1-26.6177.969.7-175.5161.700113V223 G225 R226V223-E280 PolarHBondContact O-N 2.97Å; G225-E280 PolarHBondContact N-OE1 2.86Å; R226-E280 VanDerWaalsContact CA-OE1 3.25Å; R226-E280 WeakPolarHBondContact CA-OE1 3.32Å; R226-E280 PolarHBondContact N-OE1 2.76Å
281G96.2Very high94.2Very high15 Ų1532 Ų3216%0.15519%0.186CC..THydrogen-bonded Turntrans-92.810.3176.100000115.3R226 P247 A279R226-G281 VanDerWaalsContact O-CA 3.22Å; R226-G281 WeakPolarHBondContact O-CA 3.49Å; R226-G281 PolarHBondContact O-N 3.05Å; P247-G281 WeakPolarHBondContact CB-O 3.47Å; A279-G281 PolarHBondContact O-N 2.59Å; A279-G281 VanDerWaalsContact O-N 3.13Å
282A97.3Very high94.9Very high3 Ų330.6 Ų30.63%0.02518%0.18CC..  trans-59.4137.2-173.800000113.1F245 A279 I290F245-A282 HydrophobicContact CB-CB 3.81Å; A279-A282 WeakPolarHBondContact O-CB 3.39Å; A279-A282 PolarHBondContact O-N 2.85Å; A282-I290 HydrophobicContact CB-CB 4.27Å; A282-I290 PolarHBondContact O-N 3.46Å
283V96.3Very high95.5Very high26 Ų2630.8 Ų30.816%0.15819%0.186CC..BIsolated β-bridgetrans-136.1161.3177.5-640000110.5P247 P250 P251 S288 W383P247-V283 HydrophobicContact CB-CG2 4.47Å; P250-V283 HydrophobicContact CB-CG2 4.4Å; P250-V283 WeakPolarHBondContact CB-O 3.4Å; P250-V283 HydrophobicContact CG-CG2 3.93Å; P251-V283 WeakPolarHBondContact CD-O 3.24Å; V283-S288 CarbonylContact C-O 3.35Å; V283-S288 WeakPolarHBondContact CA-O 3.43Å; V283-W383 HydrophobicContact CG2-CH2 4.07Å; V283-W383 HydrophobicContact CG2-CZ3 4.4Å
284D94.8Very high95.8Very high16 Ų1633.8 Ų33.89%0.08620%0.201CC..  trans-84.8174.816773.810.6000112P250 N286 G287 S288 I290P250-D284 WeakPolarHBondContact CB-O 3.48Å; D284-N286 PolarHBondContact O-N 2.64Å; D284-N286 VanDerWaalsContact OD1-CA 3.29Å; D284-N286 WeakPolarHBondContact OD1-CA 3.14Å; D284-N286 VanDerWaalsContact OD1-CB 3.31Å; D284-N286 WeakPolarHBondContact OD1-CB 3.21Å; D284-N286 PolarHBondContact OD1-N 3.34Å; D284-G287 PolarHBondContact O-N 3.28Å; D284-G287 PolarHBondContact OD1-N 2.87Å; D284-S288 PolarHBondContact N-O 2.82Å; D284-S288 WeakPolarHBondContact OD1-CB 3.46Å; D284-S288 PolarHBondContact OD1-N 2.93Å; D284-S288 PolarHBondContact OD1-OG 3.43Å; D284-S288 WeakPolarHBondContact OD2-CB 3.41Å; D284-S288 PolarHBondContact OD2-OG 3.22Å; D284-I290 HydrophobicContact CB-CD1 4.03Å; D284-I290 HydrophobicContact CB-CG1 4.3Å
285C93Very high96Very high38 Ų3833.8 Ų33.826%0.25720%0.201SC..THydrogen-bonded Turntrans-59.4-19.2179.164.10000114.3P251P251-C285 WeakPolarHBondContact O-CB 3.41Å; P251-C285 PolarHBondContact O-N 2.83Å; P251-C285 VanDerWaalsContact O-N 3.11Å
286N91.9Very high96.2Very high92 Ų9237.2 Ų37.249%0.49221%0.213SC..THydrogen-bonded Turntrans-89.5-4.9176.4-60.3-44000112.5D284 K381D284-N286 PolarHBondContact O-N 2.64Å; D284-N286 VanDerWaalsContact OD1-CA 3.29Å; D284-N286 WeakPolarHBondContact OD1-CA 3.14Å; D284-N286 VanDerWaalsContact OD1-CB 3.31Å; D284-N286 WeakPolarHBondContact OD1-CB 3.21Å; D284-N286 PolarHBondContact OD1-N 3.34Å; N286-K381 WeakPolarHBondContact O-CE 3.37Å; N286-K381 PolarHBondContact O-NZ 3.29Å
287G90.7Very high96.2Very high33 Ų3339.8 Ų39.834%0.3423%0.227SC..SBendtrans85.310.1-176.200000113.9D284D284-G287 PolarHBondContact O-N 3.28Å; D284-G287 PolarHBondContact OD1-N 2.87Å
288S94.3Very high96.1Very high56 Ų5640.3 Ų40.339%0.39223%0.23SC..  trans-78.1134.5177.3-440000109.8V283 D284 I290V283-S288 CarbonylContact C-O 3.35Å; V283-S288 WeakPolarHBondContact CA-O 3.43Å; D284-S288 PolarHBondContact N-O 2.82Å; D284-S288 WeakPolarHBondContact OD1-CB 3.46Å; D284-S288 PolarHBondContact OD1-N 2.93Å; D284-S288 PolarHBondContact OD1-OG 3.43Å; D284-S288 WeakPolarHBondContact OD2-CB 3.41Å; D284-S288 PolarHBondContact OD2-OG 3.22Å; S288-I290 PolarHBondContact O-N 3.48Å
289P96.1Very high96.1Very high91 Ų9140.3 Ų40.359%0.59123%0.229SC*.BIsolated β-bridgetrans-58.7138.3178.6-24.433.8000112.8
290I97.2Very high96Very high7 Ų742.8 Ų42.84%0.03624%0.242CC..  trans-108112.7169.5-61176.6000107.3F245 P251 W255 A282 D284 S288 V295F245-I290 HydrophobicContact CD1-CD1 3.75Å; F245-I290 HydrophobicContact CD1-CG2 4.12Å; F245-I290 HydrophobicContact CE1-CD1 4.01Å; F245-I290 HydrophobicContact CE1-CG2 4.29Å; F245-I290 HydrophobicContact CG-CG2 4.39Å; P251-I290 HydrophobicContact CG-CD1 3.66Å; W255-I290 HydrophobicContact CH2-CG2 4.07Å; W255-I290 HydrophobicContact CZ2-CG1 4.42Å; W255-I290 HydrophobicContact CZ2-CG2 4.09Å; A282-I290 HydrophobicContact CB-CB 4.27Å; A282-I290 PolarHBondContact O-N 3.46Å; D284-I290 HydrophobicContact CB-CD1 4.03Å; D284-I290 HydrophobicContact CB-CG1 4.3Å; S288-I290 PolarHBondContact O-N 3.48Å; I290-V295 HydrophobicContact CG2-CG2 3.73Å
291T97.1Very high96Very high61 Ų6146.1 Ų46.137%0.37426%0.257SS..  trans-95.5154.9178.272.20000111.6E293 M294 V295T291-E293 PolarHBondContact O-N 2.79Å; T291-M294 HydrophobicContact CG2-SD 4.26Å; T291-M294 WeakPolarHBondContact O-CB 3.16Å; T291-M294 PolarHBondContact O-N 3.11Å; T291-M294 VanDerWaalsContact O-N 3.15Å; T291-M294 VanDerWaalsContact OG1-CG 3.29Å; T291-M294 WeakPolarHBondContact OG1-CG 3.24Å; T291-M294 PolarHBondContact OG1-N 2.93Å; T291-M294 VanDerWaalsContact OG1-N 3.13Å; T291-V295 WeakPolarHBondContact O-CG2 3.44Å; T291-V295 PolarHBondContact O-N 2.67Å; T291-V295 VanDerWaalsContact O-N 3.14Å
292A97.1Very high96Very high2 Ų251.3 Ų51.32%0.01727%0.272CS..Hα-helixtrans-57.8-31.6173.800000112.3V220 E222 V295 R296 I309V220-A292 HydrophobicContact CG1-CB 3.74Å; E222-A292 HydrophobicContact CB-CB 4.31Å; A292-V295 PolarHBondContact O-N 3.41Å; A292-R296 WeakPolarHBondContact O-CB 2.97Å; A292-R296 PolarHBondContact O-N 2.6Å; A292-I309 HydrophobicContact CB-CG1 4.38Å; A292-I309 HydrophobicContact CB-CG2 3.93Å
293E97.6Very high95.8Very high116 Ų11652.7 Ų52.754%0.54228%0.279SS..Hα-helixtrans-68.4-43.1176.2-169.3157.1-149.600113T291 V295 R296 N297 I309T291-E293 PolarHBondContact O-N 2.79Å; E293-V295 VanDerWaalsContact C-N 3.34Å; E293-V295 PolarHBondContact O-N 2.81Å; E293-R296 PolarHBondContact O-N 3.36Å; E293-N297 WeakPolarHBondContact O-CB 3.49Å; E293-N297 PolarHBondContact O-N 3.05Å; E293-N297 PolarHBondContact O-ND2 3.17Å; E293-N297 PolarHBondContact O-OD1 3.1Å; E293-I309 HydrophobicContact CB-CD1 4.15Å
294M97.1Very high95.7Very high67 Ų6758.2 Ų58.233%0.3331%0.308SS..Hα-helixtrans-57.9-48.2173-71.1168.268.300111T291 R296 N297 I298T291-M294 HydrophobicContact CG2-SD 4.26Å; T291-M294 WeakPolarHBondContact O-CB 3.16Å; T291-M294 PolarHBondContact O-N 3.11Å; T291-M294 VanDerWaalsContact O-N 3.15Å; T291-M294 VanDerWaalsContact OG1-CG 3.29Å; T291-M294 WeakPolarHBondContact OG1-CG 3.24Å; T291-M294 PolarHBondContact OG1-N 2.93Å; T291-M294 VanDerWaalsContact OG1-N 3.13Å; M294-R296 PolarHBondContact O-N 3.11Å; M294-N297 PolarHBondContact O-N 3.25Å; M294-I298 VanDerWaalsContact O-CD1 3.26Å; M294-I298 WeakPolarHBondContact O-CD1 3.36Å; M294-I298 VanDerWaalsContact O-CG1 3.28Å; M294-I298 WeakPolarHBondContact O-CG1 3.44Å; M294-I298 PolarHBondContact O-N 2.85Å; M294-I298 VanDerWaalsContact O-N 3.11Å
295V97.5Very high95.7Very high0 Ų059.6 Ų59.60%031%0.312CS..Hα-helixtrans-59.7-46.6179176.60000111V220 F245 W255 L259 I276 I290 T291 A292 E293 I298 I299V220-V295 HydrophobicContact CG1-CB 4.2Å; V220-V295 HydrophobicContact CG1-CG1 4.09Å; V220-V295 HydrophobicContact CG2-CB 4.32Å; V220-V295 HydrophobicContact CG2-CG1 3.75Å; F245-V295 HydrophobicContact CD2-CG2 4.25Å; F245-V295 HydrophobicContact CE2-CG1 4.16Å; F245-V295 HydrophobicContact CE2-CG2 3.77Å; F245-V295 HydrophobicContact CZ-CG2 4.13Å; W255-V295 HydrophobicContact CH2-CG2 3.87Å; W255-V295 HydrophobicContact CZ3-CG2 4.01Å; L259-V295 HydrophobicContact CD2-CG1 3.88Å; I276-V295 HydrophobicContact CG2-CG1 4Å; I290-V295 HydrophobicContact CG2-CG2 3.73Å; T291-V295 WeakPolarHBondContact O-CG2 3.44Å; T291-V295 PolarHBondContact O-N 2.67Å; T291-V295 VanDerWaalsContact O-N 3.14Å; A292-V295 PolarHBondContact O-N 3.41Å; E293-V295 VanDerWaalsContact C-N 3.34Å; E293-V295 PolarHBondContact O-N 2.81Å; V295-I298 PolarHBondContact O-N 3.06Å; V295-I299 HydrophobicContact CG1-CD1 3.97Å; V295-I299 VanDerWaalsContact O-CG1 3.3Å; V295-I299 WeakPolarHBondContact O-CG1 3.25Å; V295-I299 PolarHBondContact O-N 3.44Å
296R97.5Very high95.7Very high76 Ų7660.9 Ų60.929%0.28732%0.316SS..Hα-helixtrans-57.7-50.9176.7170.6-175.2168.2-112.9-0.5111.7V220 A292 E293 M294 I298 I299 I300 T307 I309V220-R296 HydrophobicContact CG2-CB 4.43Å; A292-R296 WeakPolarHBondContact O-CB 2.97Å; A292-R296 PolarHBondContact O-N 2.6Å; E293-R296 PolarHBondContact O-N 3.36Å; M294-R296 PolarHBondContact O-N 3.11Å; R296-I298 VanDerWaalsContact C-N 3.3Å; R296-I298 PolarHBondContact O-N 3.03Å; R296-I299 PolarHBondContact O-N 3.42Å; R296-I300 HydrophobicContact CG-CD1 3.71Å; R296-I300 HydrophobicContact CG-CG1 4.41Å; R296-I300 WeakPolarHBondContact O-CG1 3.45Å; R296-I300 PolarHBondContact O-N 3.13Å; R296-T307 HydrophobicContact CB-CG2 4.18Å; R296-T307 HydrophobicContact CG-CG2 3.96Å; R296-T307 PolarHBondContact NE-O 3.46Å; R296-I309 HydrophobicContact CB-CD1 3.81Å; R296-I309 HydrophobicContact CB-CG1 3.88Å; R296-I309 HydrophobicContact CG-CD1 4.29Å; R296-I309 HydrophobicContact CG-CG1 4.36Å
297N97.5Very high95.9Very high54 Ų5456.5 Ų56.529%0.28929%0.293SS..Hα-helixtrans-62.1-41.9-174-67.2-10.9000110.7E293 M294 I299 I300 E301E293-N297 WeakPolarHBondContact O-CB 3.49Å; E293-N297 PolarHBondContact O-N 3.05Å; E293-N297 PolarHBondContact O-ND2 3.17Å; E293-N297 PolarHBondContact O-OD1 3.1Å; M294-N297 PolarHBondContact O-N 3.25Å; N297-I299 PolarHBondContact O-N 3.25Å; N297-I300 PolarHBondContact O-N 2.77Å; N297-E301 WeakPolarHBondContact O-CB 3.07Å; N297-E301 VanDerWaalsContact O-CG 3.24Å; N297-E301 WeakPolarHBondContact O-CG 3.46Å; N297-E301 PolarHBondContact O-N 3.22Å
298I96.7Very high96.2Very high12 Ų1259.5 Ų59.56%0.06229%0.294CS..Hα-helixtrans-59.6-44175.9-69157.8000111.9W255 R256 M294 V295 R296 R302W255-I298 HydrophobicContact CH2-CD1 3.2Å; W255-I298 HydrophobicContact CZ2-CD1 3.7Å; W255-I298 HydrophobicContact CZ3-CD1 3.8Å; R256-I298 HydrophobicContact CB-CD1 4.4Å; R256-I298 HydrophobicContact CB-CG2 4.13Å; R256-I298 HydrophobicContact CG-CD1 3.7Å; R256-I298 HydrophobicContact CG-CG1 4.46Å; M294-I298 VanDerWaalsContact O-CD1 3.26Å; M294-I298 WeakPolarHBondContact O-CD1 3.36Å; M294-I298 VanDerWaalsContact O-CG1 3.28Å; M294-I298 WeakPolarHBondContact O-CG1 3.44Å; M294-I298 PolarHBondContact O-N 2.85Å; M294-I298 VanDerWaalsContact O-N 3.11Å; V295-I298 PolarHBondContact O-N 3.06Å; R296-I298 VanDerWaalsContact C-N 3.3Å; R296-I298 PolarHBondContact O-N 3.03Å; I298-R302 WeakPolarHBondContact O-CB 3.38Å; I298-R302 PolarHBondContact O-N 3.2Å
299I96.7Very high96.3Very high0 Ų059.5 Ų59.50%029%0.289CS..Hα-helixtrans-65.1-42.1179.5-64.1167.5000110.6V220 L259 L263 I276 V295 R296 N297 L303 N304 Y305 T307V220-I299 HydrophobicContact CG2-CD1 4.3Å; L259-I299 HydrophobicContact CD2-CD1 4.26Å; L259-I299 HydrophobicContact CD2-CG1 4.11Å; L263-I299 HydrophobicContact CD1-CD1 3.62Å; L263-I299 HydrophobicContact CD1-CG1 3.77Å; L263-I299 HydrophobicContact CD1-CG2 4.37Å; I276-I299 HydrophobicContact CD1-CD1 3.86Å; I276-I299 HydrophobicContact CG1-CD1 4.35Å; V295-I299 HydrophobicContact CG1-CD1 3.97Å; V295-I299 VanDerWaalsContact O-CG1 3.3Å; V295-I299 WeakPolarHBondContact O-CG1 3.25Å; V295-I299 PolarHBondContact O-N 3.44Å; R296-I299 PolarHBondContact O-N 3.42Å; N297-I299 PolarHBondContact O-N 3.25Å; I299-L303 HydrophobicContact CG2-CD1 4.45Å; I299-L303 WeakPolarHBondContact O-CA 3.38Å; I299-L303 WeakPolarHBondContact O-CB 3.32Å; I299-L303 PolarHBondContact O-N 2.99Å; I299-N304 PolarHBondContact O-N 3.34Å; I299-Y305 HydrophobicContact CG2-CD2 4.31Å; I299-T307 HydrophobicContact CB-CG2 4.43Å; I299-T307 HydrophobicContact CD1-CG2 4.22Å; I299-T307 HydrophobicContact CG2-CG2 4.42Å; I299-T307 WeakPolarHBondContact CG2-OG1 3.36Å
300I96.7Very high96.3Very high54 Ų5457 Ų5728%0.27727%0.273SS..Hα-helixtrans-66-51.1178.2-67.4173.3000110.4R296 N297 R302 N304R296-I300 HydrophobicContact CG-CD1 3.71Å; R296-I300 HydrophobicContact CG-CG1 4.41Å; R296-I300 WeakPolarHBondContact O-CG1 3.45Å; R296-I300 PolarHBondContact O-N 3.13Å; N297-I300 PolarHBondContact O-N 2.77Å; I300-R302 PolarHBondContact O-N 3.25Å; I300-N304 WeakPolarHBondContact O-CA 3.4Å; I300-N304 PolarHBondContact O-N 3.44Å
301E96.3Very high96.3Very high149 Ų14960.7 Ų60.770%0.69630%0.295SS*.Hα-helixtrans-64.9-40.5-174.9-72.1167.4-164.100112.7N297N297-E301 WeakPolarHBondContact O-CB 3.07Å; N297-E301 VanDerWaalsContact O-CG 3.24Å; N297-E301 WeakPolarHBondContact O-CG 3.46Å; N297-E301 PolarHBondContact O-N 3.22Å
302R96.2Very high96.3Very high124 Ų12458.6 Ų58.647%0.46828%0.281SS..Hα-helixtrans-96.1-31.2-173.2-63.7-172.6173.7-160.7-6.9114.7D257 I298 I300D257-R302 IonicContact OD1-CZ 3.57Å; D257-R302 IonicContact OD1-NH1 3.27Å; D257-R302 PolarHBondContact OD1-NH1 3.31Å; D257-R302 IonicContact OD1-NH2 2.78Å; D257-R302 IonicContact OD2-NH1 3.66Å; I298-R302 WeakPolarHBondContact O-CB 3.38Å; I298-R302 PolarHBondContact O-N 3.2Å; I300-R302 PolarHBondContact O-N 3.25Å
303L94.5Very high96.2Very high32 Ų3259.4 Ų59.417%0.16829%0.29CS..Hα-helixtrans-112.6-12.2-176.7-58.9-179.5000113.6C260 L263 H264 I299 Y305C260-L303 HydrophobicContact CB-CD1 4.27Å; C260-L303 HydrophobicContact CB-CD2 4.08Å; C260-L303 HydrophobicContact CB-CG 4.17Å; L263-L303 HydrophobicContact CB-CD1 3.78Å; L263-L303 HydrophobicContact CD1-CD1 4.41Å; H264-L303 HydrophobicContact CB-CD2 4.03Å; I299-L303 HydrophobicContact CG2-CD1 4.45Å; I299-L303 WeakPolarHBondContact O-CA 3.38Å; I299-L303 WeakPolarHBondContact O-CB 3.32Å; I299-L303 PolarHBondContact O-N 2.99Å; L303-Y305 HydrophobicContact CB-CD1 4.06Å; L303-Y305 HydrophobicContact CB-CD2 3.92Å; L303-Y305 HydrophobicContact CB-CE1 4.17Å; L303-Y305 HydrophobicContact CB-CE2 4.04Å; L303-Y305 HydrophobicContact CB-CG 3.93Å; L303-Y305 HydrophobicContact CD1-CD2 3.89Å; L303-Y305 HydrophobicContact CD1-CE2 3.69Å; L303-Y305 HydrophobicContact CG-CE2 4.45Å; L303-Y305 WeakPolarHBondContact O-CD1 3.23Å; L303-Y305 WeakPolarHBondContact O-CE1 3.42Å; L303-Y305 PolarHBondContact O-N 3.37Å
304N93.9Very high96.1Very high143 Ų14360.6 Ų60.677%0.76530%0.295SS*.  trans55.133-175.2-162.734.3000113.4I299 I300I299-N304 PolarHBondContact O-N 3.34Å; I300-N304 WeakPolarHBondContact O-CA 3.4Å; I300-N304 PolarHBondContact O-N 3.44Å
305Y93.6Very high96Very high44 Ų4461.3 Ų61.317%0.17330%0.303CS..  trans-88.4135.7176.6-66-10.2000110.9L263 H264 R267 I299 L303 T307L263-Y305 HydrophobicContact CB-CE2 4.5Å; H264-Y305 PolarHBondContact ND1-OH 3.1Å; R267-Y305 HydrophobicContact CB-CE2 4.49Å; R267-Y305 HydrophobicContact CG-CE2 3.68Å; I299-Y305 HydrophobicContact CG2-CD2 4.31Å; L303-Y305 HydrophobicContact CB-CD1 4.06Å; L303-Y305 HydrophobicContact CB-CD2 3.92Å; L303-Y305 HydrophobicContact CB-CE1 4.17Å; L303-Y305 HydrophobicContact CB-CE2 4.04Å; L303-Y305 HydrophobicContact CB-CG 3.93Å; L303-Y305 HydrophobicContact CD1-CD2 3.89Å; L303-Y305 HydrophobicContact CD1-CE2 3.69Å; L303-Y305 HydrophobicContact CG-CE2 4.45Å; L303-Y305 WeakPolarHBondContact O-CD1 3.23Å; L303-Y305 WeakPolarHBondContact O-CE1 3.42Å; L303-Y305 PolarHBondContact O-N 3.37Å; Y305-T307 PolarHBondContact O-N 3.31Å; Y305-T307 PolarHBondContact O-OG1 3.29Å
306D94.2Very high96Very high65 Ų6561.3 Ų61.335%0.34830%0.303SS..  trans-64.4101.7175.3-172.124.9000110.2R217 S218 R308R217-D306 WeakPolarHBondContact CA-O 3.48Å; R217-D306 HydrophobicContact CG-CB 4.09Å; R217-D306 IonicContact CZ-OD2 3.55Å; R217-D306 IonicContact NE-OD2 2.74Å; R217-D306 PolarHBondContact NE-OD2 2.88Å; R217-D306 IonicContact NH2-OD2 3.56Å; S218-D306 PolarHBondContact N-O 3.43Å; D306-R308 IonicContact OD1-CZ 2.72Å; D306-R308 IonicContact OD1-NH1 2.69Å; D306-R308 PolarHBondContact OD1-NH1 2.9Å; D306-R308 IonicContact OD1-NH2 2.91Å; D306-R308 PolarHBondContact OD1-NH2 3.28Å; D306-R308 IonicContact OD2-NH2 2.82Å; D306-R308 PolarHBondContact OD2-NH2 3.09Å
307T95.9Very high95.9Very high0 Ų059.8 Ų59.80%030%0.297CS..EExtended strand (participates in β ladder)trans-115.2132.2-169.3-530000111.6S218 V220 R296 I299 Y305S218-T307 VanDerWaalsContact O-CA 3.26Å; S218-T307 WeakPolarHBondContact O-CA 3.21Å; V220-T307 HydrophobicContact CG2-CG2 3.98Å; R296-T307 HydrophobicContact CB-CG2 4.18Å; R296-T307 HydrophobicContact CG-CG2 3.96Å; R296-T307 PolarHBondContact NE-O 3.46Å; I299-T307 HydrophobicContact CB-CG2 4.43Å; I299-T307 HydrophobicContact CD1-CG2 4.22Å; I299-T307 HydrophobicContact CG2-CG2 4.42Å; I299-T307 WeakPolarHBondContact CG2-OG1 3.36Å; Y305-T307 PolarHBondContact O-N 3.31Å; Y305-T307 PolarHBondContact O-OG1 3.29Å
308R96.2Very high95.6Very high96 Ų9658.4 Ų58.436%0.36230%0.296SS..EExtended strand (participates in β ladder)trans-121.8150.4178.4-65.2-67.5174.8-79.1-10.8110.9S218 F219 V220 D306S218-R308 PolarHBondContact O-N 2.66Å; F219-R308 CarbonylContact C-O 3.58Å; F219-R308 WeakPolarHBondContact CA-O 3.1Å; F219-R308 HydrophobicContact CD1-CB 3.85Å; F219-R308 HydrophobicContact CE1-CB 3.66Å; F219-R308 HydrophobicContact CE1-CG 4.33Å; F219-R308 HydrophobicContact CZ-CB 4.21Å; F219-R308 HydrophobicContact CZ-CG 4.45Å; V220-R308 PolarHBondContact N-O 3.24Å; D306-R308 IonicContact OD1-CZ 2.72Å; D306-R308 IonicContact OD1-NH1 2.69Å; D306-R308 PolarHBondContact OD1-NH1 2.9Å; D306-R308 IonicContact OD1-NH2 2.91Å; D306-R308 PolarHBondContact OD1-NH2 3.28Å; D306-R308 IonicContact OD2-NH2 2.82Å; D306-R308 PolarHBondContact OD2-NH2 3.09Å
309I97Very high95.4Very high56 Ų5659.2 Ų59.229%0.28731%0.308SS..EExtended strand (participates in β ladder)trans-102.3141.2172.1-65.1159.9000108.2V220 A292 E293 R296 V311V220-I309 HydrophobicContact CB-CG1 4.28Å; V220-I309 CarbonylContact O-C 3.54Å; V220-I309 VanDerWaalsContact O-CA 3.3Å; V220-I309 WeakPolarHBondContact O-CA 3.44Å; A292-I309 HydrophobicContact CB-CG1 4.38Å; A292-I309 HydrophobicContact CB-CG2 3.93Å; E293-I309 HydrophobicContact CB-CD1 4.15Å; R296-I309 HydrophobicContact CB-CD1 3.81Å; R296-I309 HydrophobicContact CB-CG1 3.88Å; R296-I309 HydrophobicContact CG-CD1 4.29Å; R296-I309 HydrophobicContact CG-CG1 4.36Å; I309-V311 HydrophobicContact CG2-CG2 3.85Å
310T96.6Very high95.3Very high40 Ų4064 Ų6425%0.24533%0.333CS..EExtended strand (participates in β ladder)trans-130.6104.5170.2-57.10000108.2V220 V221 E222 L312V220-T310 PolarHBondContact O-N 2.94Å; V221-T310 WeakPolarHBondContact CA-O 3.3Å; E222-T310 PolarHBondContact N-O 3.41Å; T310-L312 HydrophobicContact CG2-CD2 3.95Å
311V97.2Very high95.4Very high83 Ų8361.5 Ų61.550%0.50332%0.321SS..EExtended strand (participates in β ladder)trans-88.1109.3172.5-175.80000107.8E222 I309 G313E222-V311 HydrophobicContact CB-CB 4.38Å; E222-V311 HydrophobicContact CB-CG1 4.3Å; E222-V311 HydrophobicContact CB-CG2 4.05Å; I309-V311 HydrophobicContact CG2-CG2 3.85Å; V311-G313 VanDerWaalsContact C-N 3.32Å; V311-G313 PolarHBondContact O-N 3.34Å
312L96.5Very high95.5Very high17 Ų1754.6 Ų54.69%0.08929%0.289CS..  trans-67-38.1-177.7-60.2-173.8000111.3I201 A204 V221 E222 V223 T310 H314 V315 Q316I201-L312 HydrophobicContact CB-CD1 4.21Å; I201-L312 HydrophobicContact CG1-CD1 3.95Å; I201-L312 HydrophobicContact CG2-CD1 4.19Å; A204-L312 HydrophobicContact CB-CD1 4.16Å; A204-L312 HydrophobicContact CB-CD2 3.41Å; A204-L312 VanDerWaalsContact CB-CD2 3.41Å; A204-L312 HydrophobicContact CB-CG 4.45Å; V221-L312 HydrophobicContact CG1-CD1 4.02Å; V221-L312 HydrophobicContact CG1-CD2 4.18Å; V221-L312 HydrophobicContact CG1-CG 3.92Å; E222-L312 PolarHBondContact O-N 3.42Å; V223-L312 HydrophobicContact CG1-CD1 4.14Å; T310-L312 HydrophobicContact CG2-CD2 3.95Å; L312-H314 PolarHBondContact O-N 2.98Å; L312-V315 HydrophobicContact CB-CG2 3.97Å; L312-V315 WeakPolarHBondContact O-CG2 3.26Å; L312-Q316 HydrophobicContact CB-CG 3.99Å; L312-Q316 HydrophobicContact CD1-CG 4.26Å
313G95Very high95.5Very high19 Ų1948.8 Ų48.820%0.19627%0.267CS..G310 helixtrans56.6-138.4-179.600000112.2V311 V315 Q316V311-G313 VanDerWaalsContact C-N 3.32Å; V311-G313 PolarHBondContact O-N 3.34Å; G313-V315 PolarHBondContact O-N 3.31Å; G313-Q316 WeakPolarHBondContact O-CB 3.41Å; G313-Q316 WeakPolarHBondContact O-CG 3.32Å; G313-Q316 PolarHBondContact O-N 3.04Å; G313-Q316 PolarHBondContact O-NE2 3.25Å
314H94.9Very high95.7Very high141 Ų14149.3 Ų49.365%0.65327%0.268SS*.G310 helixtrans-74.2-5.3-168.8-67.483.7000115.2L312 Q316 R317 G318L312-H314 PolarHBondContact O-N 2.98Å; H314-Q316 PolarHBondContact O-N 3.41Å; H314-Q316 VanDerWaalsContact O-N 3.07Å; H314-R317 PolarHBondContact O-N 2.95Å; H314-G318 PolarHBondContact O-N 3.38Å
315V96Very high95.9Very high82 Ų8242.5 Ų42.550%0.49723%0.231SC..G310 helixtrans-58.2-23169.7-53.10000111.4R200 L312 G313R200-V315 VanDerWaalsContact CG-O 3.26Å; R200-V315 WeakPolarHBondContact CG-O 3.42Å; L312-V315 HydrophobicContact CB-CG2 3.97Å; L312-V315 WeakPolarHBondContact O-CG2 3.26Å; G313-V315 PolarHBondContact O-N 3.31Å
316Q97.4Very high96.1Very high1 Ų140.8 Ų40.81%0.00523%0.225CC..G310 helixtrans-72.6-21.8175.4-62.5170.992.600113.8Q44 I181 A197 I201 M224 L312 G313 H314Q44-Q316 PolarHBondContact NE2-O 3.09Å; I181-Q316 HydrophobicContact CD1-CB 4.35Å; A197-Q316 WeakPolarHBondContact CB-O 3.35Å; I201-Q316 HydrophobicContact CG1-CG 3.96Å; M224-Q316 HydrophobicContact SD-CB 4.39Å; L312-Q316 HydrophobicContact CB-CG 3.99Å; L312-Q316 HydrophobicContact CD1-CG 4.26Å; G313-Q316 WeakPolarHBondContact O-CB 3.41Å; G313-Q316 WeakPolarHBondContact O-CG 3.32Å; G313-Q316 PolarHBondContact O-N 3.04Å; G313-Q316 PolarHBondContact O-NE2 3.25Å; H314-Q316 PolarHBondContact O-N 3.41Å; H314-Q316 VanDerWaalsContact O-N 3.07Å
317R94.7Very high96.2Very high43 Ų4338.5 Ų38.516%0.16221%0.212CC..THydrogen-bonded Turntrans-95-17.8175.2-65.4-169.2-162.6-85.5-8.6113.3Q44 I181 M224 H314Q44-R317 WeakPolarHBondContact CG-O 3.49Å; Q44-R317 PolarHBondContact NE2-O 2.97Å; Q44-R317 VanDerWaalsContact NE2-O 3.15Å; I181-R317 HydrophobicContact CD1-CG 3.84Å; M224-R317 HydrophobicContact SD-CG 4.33Å; H314-R317 PolarHBondContact O-N 2.95Å
318G92.6Very high96.3Very high25 Ų2538.6 Ų38.626%0.25821%0.213SC..  trans-93.8-179.818000000114.5Q44 H314Q44-G318 PolarHBondContact NE2-O 2.94Å; H314-G318 PolarHBondContact O-N 3.38Å
319G91.9Very high96.4Very high30 Ų3034 Ų3431%0.30920%0.196SC..SBendtrans91.6159.7177.400000113.6Q44 S96Q44-G319 WeakPolarHBondContact CG-O 3.31Å; S96-G319 WeakPolarHBondContact CB-O 3.42Å; S96-G319 PolarHBondContact OG-N 3.42Å; S96-G319 PolarHBondContact OG-O 3.4Å; S96-G319 VanDerWaalsContact OG-O 3.07Å
320N94.9Very high96.4Very high99 Ų9931.3 Ų31.353%0.52918%0.182SC..PPolyproline II helixtrans-64.7139.9179.9-65.9-7.4000109.8Q94 T196Q94-N320 VanDerWaalsContact O-CG 3.3Å; Q94-N320 PolarHBondContact O-OD1 3.03Å; T196-N320 WeakPolarHBondContact CG2-O 3.42Å
321P97.7Very high96.4Very high3 Ų330.2 Ų30.22%0.01917%0.173CC..PPolyproline II helixtrans-61.3144178.724.2-31.4000111.2Q44 I93 Q94 T196 D325 R326Q44-P321 HydrophobicContact CB-CB 3.99Å; I93-P321 WeakPolarHBondContact O-CG 3.5Å; Q94-P321 WeakPolarHBondContact O-CD 3.38Å; T196-P321 WeakPolarHBondContact OG1-CA 3.37Å; P321-D325 HydrophobicContact CB-CB 4.26Å; P321-R326 HydrophobicContact CB-CG 3.9Å; P321-R326 HydrophobicContact CG-CG 3.71Å; P321-R326 PolarHBondContact O-NE 2.85Å; P321-R326 PolarHBondContact O-NH2 2.74Å; P321-R326 VanDerWaalsContact O-NH2 3.1Å
322S98.1Very high96.4Very high4 Ų426.5 Ų26.53%0.02815%0.15CC..PPolyproline II helixtrans-61.4162.6171.172.90000111.2D195 T196 F324 D325 R326 N568D195-S322 WeakPolarHBondContact OD2-CB 3.31Å; D195-S322 PolarHBondContact OD2-OG 3.36Å; T196-S322 PolarHBondContact OG1-N 3.47Å; S322-F324 PolarHBondContact O-N 2.83Å; S322-F324 PolarHBondContact OG-N 3.16Å; S322-D325 PolarHBondContact O-N 3.17Å; S322-D325 PolarHBondContact OG-N 3.24Å; S322-D325 VanDerWaalsContact OG-N 3.14Å; S322-R326 VanDerWaalsContact O-CG 3.27Å; S322-R326 WeakPolarHBondContact O-CG 3.42Å; S322-R326 PolarHBondContact O-N 2.77Å; S322-R326 VanDerWaalsContact O-N 3.08Å; S322-N568 WeakPolarHBondContact CA-OD1 3.47Å; S322-N568 WeakPolarHBondContact CB-OD1 3.34Å
323A97.8Very high96.4Very high1 Ų125.7 Ų25.71%0.00815%0.146CC..Hα-helixtrans-56.9-39.4174.400000111.3R326 L327 L567 N568A323-R326 PolarHBondContact O-N 3.11Å; A323-L327 WeakPolarHBondContact O-CB 3.48Å; A323-L327 VanDerWaalsContact O-CG 3.24Å; A323-L327 WeakPolarHBondContact O-CG 3.48Å; A323-L327 PolarHBondContact O-N 2.94Å; A323-L567 HydrophobicContact CB-CB 3.87Å; A323-N568 PolarHBondContact N-OD1 3.47Å
324F97.3Very high96.5Very high43 Ų4325 Ų2519%0.18914%0.138CC..Hα-helixtrans-61.3-51.1177-178-89.7000112.1M190 D195 S322 R326 L327 L328M190-F324 HydrophobicContact CB-CE1 4.09Å; M190-F324 HydrophobicContact CB-CZ 4.2Å; M190-F324 HydrophobicContact CG-CE1 3.69Å; M190-F324 HydrophobicContact CG-CZ 4.24Å; D195-F324 HydrophobicContact CB-CB 4.35Å; D195-F324 HydrophobicContact CB-CD1 3.74Å; D195-F324 HydrophobicContact CB-CG 4.35Å; S322-F324 PolarHBondContact O-N 2.83Å; S322-F324 PolarHBondContact OG-N 3.16Å; F324-R326 VanDerWaalsContact C-N 3.3Å; F324-R326 PolarHBondContact O-N 3.38Å; F324-L327 PolarHBondContact O-N 2.91Å; F324-L327 VanDerWaalsContact O-N 3.16Å; F324-L328 HydrophobicContact CD1-CB 4.47Å; F324-L328 HydrophobicContact CE1-CB 4.19Å; F324-L328 HydrophobicContact CE1-CD2 3.79Å; F324-L328 HydrophobicContact CE1-CG 4.42Å; F324-L328 HydrophobicContact CZ-CD2 4.42Å; F324-L328 VanDerWaalsContact O-CB 3.3Å; F324-L328 WeakPolarHBondContact O-CB 3.41Å; F324-L328 PolarHBondContact O-N 3.16Å
325D98.1Very high96.6Very high0 Ų018.6 Ų18.60%011%0.109CC..Hα-helixtrans-67-30.8-178.4-81.2-40.1000112.8G193 T196 P321 S322 G329G193-D325 WeakPolarHBondContact CA-OD2 3.5Å; G193-D325 PolarHBondContact N-OD1 3.43Å; G193-D325 PolarHBondContact N-OD2 3.29Å; T196-D325 VanDerWaalsContact CB-OD2 3.29Å; T196-D325 WeakPolarHBondContact CB-OD2 3.41Å; T196-D325 PolarHBondContact N-OD2 3.46Å; T196-D325 PolarHBondContact OG1-OD2 3.01Å; P321-D325 HydrophobicContact CB-CB 4.26Å; S322-D325 PolarHBondContact O-N 3.17Å; S322-D325 PolarHBondContact OG-N 3.24Å; S322-D325 VanDerWaalsContact OG-N 3.14Å; D325-G329 PolarHBondContact O-N 3.01Å
326R98.2Very high96.7Very high9 Ų914.7 Ų14.73%0.0349%0.085CC..Hα-helixtrans-65-45.6171.4-66.2178.1-155.1-157.6-2.8111.7I93 P321 S322 A323 F324 S330 D575 A608I93-R326 HydrophobicContact CG1-CB 4.29Å; I93-R326 HydrophobicContact CG1-CG 4.27Å; P321-R326 HydrophobicContact CB-CG 3.9Å; P321-R326 HydrophobicContact CG-CG 3.71Å; P321-R326 PolarHBondContact O-NE 2.85Å; P321-R326 PolarHBondContact O-NH2 2.74Å; P321-R326 VanDerWaalsContact O-NH2 3.1Å; S322-R326 VanDerWaalsContact O-CG 3.27Å; S322-R326 WeakPolarHBondContact O-CG 3.42Å; S322-R326 PolarHBondContact O-N 2.77Å; S322-R326 VanDerWaalsContact O-N 3.08Å; A323-R326 PolarHBondContact O-N 3.11Å; F324-R326 VanDerWaalsContact C-N 3.3Å; F324-R326 PolarHBondContact O-N 3.38Å; R326-S330 VanDerWaalsContact O-CB 3.28Å; R326-S330 WeakPolarHBondContact O-CB 3.41Å; R326-S330 PolarHBondContact O-N 3Å; R326-S330 PolarHBondContact O-OG 2.74Å; R326-D575 IonicContact CZ-OD2 3.82Å; R326-D575 IonicContact NH1-OD1 2.68Å; R326-D575 PolarHBondContact NH1-OD1 3.35Å; R326-D575 IonicContact NH1-OD2 3.33Å; R326-D575 PolarHBondContact NH1-OD2 3.06Å; R326-D575 IonicContact NH2-OD2 2.74Å; R326-D575 PolarHBondContact NH2-OD2 2.91Å; R326-A608 HydrophobicContact CB-CB 4.26Å; R326-A608 WeakPolarHBondContact CD-O 3.49Å
327L97.3Very high96.7Very high16 Ų1614.7 Ų14.78%0.0849%0.085CC..Hα-helixtrans-66.2-47.4177.6-71.7169000110.9A323 F324 S330 R331 L604 L607 A608A323-L327 WeakPolarHBondContact O-CB 3.48Å; A323-L327 VanDerWaalsContact O-CG 3.24Å; A323-L327 WeakPolarHBondContact O-CG 3.48Å; A323-L327 PolarHBondContact O-N 2.94Å; F324-L327 PolarHBondContact O-N 2.91Å; F324-L327 VanDerWaalsContact O-N 3.16Å; L327-S330 PolarHBondContact O-N 3.15Å; L327-R331 WeakPolarHBondContact O-CB 3.47Å; L327-R331 WeakPolarHBondContact O-CD 3.43Å; L327-R331 WeakPolarHBondContact O-CG 3.3Å; L327-R331 PolarHBondContact O-N 3.44Å; L327-L604 HydrophobicContact CD1-CB 4.34Å; L327-L604 HydrophobicContact CD1-CD2 4.09Å; L327-L604 HydrophobicContact CD2-CD2 3.96Å; L327-L607 HydrophobicContact CD2-CB 3.88Å; L327-L607 HydrophobicContact CD2-CD2 3.73Å; L327-L607 HydrophobicContact CD2-CG 3.73Å; L327-A608 HydrophobicContact CD1-CB 4.41Å; L327-A608 HydrophobicContact CD2-CB 3.87Å; L327-A608 HydrophobicContact CG-CB 3.8Å
328L97.1Very high96.7Very high2 Ų213 Ų131%0.018%0.08CC..Hα-helixtrans-58.3-52.9179.7-174.966.7000110.5I192 F324 S330 R331 M332 I354I192-L328 HydrophobicContact CG1-CD2 3.85Å; I192-L328 HydrophobicContact CG1-CG 4.06Å; F324-L328 HydrophobicContact CD1-CB 4.47Å; F324-L328 HydrophobicContact CE1-CB 4.19Å; F324-L328 HydrophobicContact CE1-CD2 3.79Å; F324-L328 HydrophobicContact CE1-CG 4.42Å; F324-L328 HydrophobicContact CZ-CD2 4.42Å; F324-L328 VanDerWaalsContact O-CB 3.3Å; F324-L328 WeakPolarHBondContact O-CB 3.41Å; F324-L328 PolarHBondContact O-N 3.16Å; L328-S330 VanDerWaalsContact C-N 3.33Å; L328-S330 PolarHBondContact O-N 3.49Å; L328-R331 PolarHBondContact O-N 3.5Å; L328-M332 HydrophobicContact CD1-CE 3.52Å; L328-M332 HydrophobicContact CD1-CG 4.16Å; L328-M332 HydrophobicContact CD1-SD 3.8Å; L328-M332 HydrophobicContact CD2-CE 4.41Å; L328-M332 HydrophobicContact CD2-SD 4.31Å; L328-M332 HydrophobicContact CG-CE 4.05Å; L328-M332 HydrophobicContact CG-CG 4.39Å; L328-M332 HydrophobicContact CG-SD 3.74Å; L328-M332 VanDerWaalsContact O-CB 3.31Å; L328-M332 WeakPolarHBondContact O-CB 3.25Å; L328-M332 VanDerWaalsContact O-CG 3.28Å; L328-M332 WeakPolarHBondContact O-CG 3.33Å; L328-M332 PolarHBondContact O-N 3.25Å; L328-I354 HydrophobicContact CD1-CB 3.95Å; L328-I354 HydrophobicContact CD1-CD1 3.71Å; L328-I354 HydrophobicContact CD1-CG1 4.44Å; L328-I354 HydrophobicContact CD1-CG2 3.88Å
329G97.2Very high96.8Very high0 Ų011.8 Ų11.80%07%0.067CC..Hα-helixtrans-57.9-45.7176.500000111.9A49 D325 R331 M332 G333A49-G329 VanDerWaalsContact CA-O 3.24Å; A49-G329 WeakPolarHBondContact CA-O 3.2Å; D325-G329 PolarHBondContact O-N 3.01Å; G329-R331 PolarHBondContact O-N 3.25Å; G329-M332 PolarHBondContact O-N 3.04Å; G329-G333 PolarHBondContact O-N 2.81Å
330S97.2Very high97Very high0 Ų010.4 Ų10.40%05%0.053CC..Hα-helixtrans-62.8-42.2-179.7-60.90000113A52 R326 L327 L328 A334A52-S330 WeakPolarHBondContact CB-O 3.48Å; R326-S330 VanDerWaalsContact O-CB 3.28Å; R326-S330 WeakPolarHBondContact O-CB 3.41Å; R326-S330 PolarHBondContact O-N 3Å; R326-S330 PolarHBondContact O-OG 2.74Å; L327-S330 PolarHBondContact O-N 3.15Å; L328-S330 VanDerWaalsContact C-N 3.33Å; L328-S330 PolarHBondContact O-N 3.49Å; S330-A334 WeakPolarHBondContact O-CB 3.47Å; S330-A334 PolarHBondContact O-N 2.79Å
331R97Very high96.9Very high17 Ų176.8 Ų6.86%0.0643%0.033CC..Hα-helixtrans-69-49.1179.3-68.9167.769.7-170.11.8111.1E20 L327 L328 G329 A334 E335 G357 V359 L767 L770E20-R331 VanDerWaalsContact CD-NH2 3.34Å; E20-R331 WeakPolarHBondContact OE1-CB 3.43Å; E20-R331 IonicContact OE1-CZ 3.13Å; E20-R331 IonicContact OE1-NE 2.84Å; E20-R331 PolarHBondContact OE1-NE 2.66Å; E20-R331 IonicContact OE1-NH2 3.11Å; E20-R331 PolarHBondContact OE1-NH2 2.66Å; E20-R331 VanDerWaalsContact OE1-NH2 3.13Å; E20-R331 IonicContact OE2-CZ 2.66Å; E20-R331 IonicContact OE2-NE 3.75Å; E20-R331 IonicContact OE2-NH2 3.36Å; E20-R331 PolarHBondContact OE2-NH2 2.73Å; L327-R331 WeakPolarHBondContact O-CB 3.47Å; L327-R331 WeakPolarHBondContact O-CD 3.43Å; L327-R331 WeakPolarHBondContact O-CG 3.3Å; L327-R331 PolarHBondContact O-N 3.44Å; L328-R331 PolarHBondContact O-N 3.5Å; G329-R331 PolarHBondContact O-N 3.25Å; R331-A334 PolarHBondContact O-N 3.03Å; R331-E335 PolarHBondContact O-N 3.3Å; R331-G357 PolarHBondContact NH1-O 2.88Å; R331-G357 PolarHBondContact NH2-O 3.3Å; R331-V359 HydrophobicContact CB-CG2 4Å; R331-L767 HydrophobicContact CG-CD2 4.38Å; R331-L770 HydrophobicContact CG-CD2 4.14Å
332M97.4Very high96.5Very high4 Ų48.5 Ų8.52%0.024%0.042CC..Hα-helixtrans-65-41.5-179.8-71.4-177.7158.800112.5L177 I192 L328 G329 A334 E335 A336 I352 A353 I354L177-M332 HydrophobicContact CD2-CB 3.88Å; I192-M332 HydrophobicContact CD1-SD 3.88Å; I192-M332 HydrophobicContact CG1-SD 3.92Å; L328-M332 HydrophobicContact CD1-CE 3.52Å; L328-M332 HydrophobicContact CD1-CG 4.16Å; L328-M332 HydrophobicContact CD1-SD 3.8Å; L328-M332 HydrophobicContact CD2-CE 4.41Å; L328-M332 HydrophobicContact CD2-SD 4.31Å; L328-M332 HydrophobicContact CG-CE 4.05Å; L328-M332 HydrophobicContact CG-CG 4.39Å; L328-M332 HydrophobicContact CG-SD 3.74Å; L328-M332 VanDerWaalsContact O-CB 3.31Å; L328-M332 WeakPolarHBondContact O-CB 3.25Å; L328-M332 VanDerWaalsContact O-CG 3.28Å; L328-M332 WeakPolarHBondContact O-CG 3.33Å; L328-M332 PolarHBondContact O-N 3.25Å; G329-M332 PolarHBondContact O-N 3.04Å; M332-A334 PolarHBondContact O-N 3.44Å; M332-E335 PolarHBondContact O-N 2.95Å; M332-A336 WeakPolarHBondContact O-CB 3.47Å; M332-A336 PolarHBondContact O-N 2.96Å; M332-I352 HydrophobicContact CB-CB 4.48Å; M332-I352 HydrophobicContact CB-CG2 4.03Å; M332-I352 HydrophobicContact CG-CG2 3.94Å; M332-A353 VanDerWaalsContact CE-C 3.41Å; M332-I354 HydrophobicContact CE-CB 4Å; M332-I354 HydrophobicContact CE-CG2 4.16Å
333G97.6Very high95.9Very high0 Ų09.6 Ų9.60%05%0.049CC..Hα-helixtrans-63.8-40.1179.200000113.1V53 G329 A336 V337V53-G333 WeakPolarHBondContact CG2-O 3.44Å; G329-G333 PolarHBondContact O-N 2.81Å; G333-A336 PolarHBondContact O-N 3.3Å; G333-V337 PolarHBondContact O-N 3.19Å
334A96.9Very high95.3Very high4 Ų413.2 Ų13.23%0.0337%0.072CC..Hα-helixtrans-68.2-41.6175.300000112.4A52 M56 S330 R331 M332 A336 V337 T338 L770A52-A334 HydrophobicContact CB-CB 4.49Å; M56-A334 HydrophobicContact CB-CB 4.32Å; M56-A334 HydrophobicContact CE-CB 3.95Å; M56-A334 HydrophobicContact CG-CB 4.35Å; S330-A334 WeakPolarHBondContact O-CB 3.47Å; S330-A334 PolarHBondContact O-N 2.79Å; R331-A334 PolarHBondContact O-N 3.03Å; M332-A334 PolarHBondContact O-N 3.44Å; A334-A336 VanDerWaalsContact C-N 3.29Å; A334-A336 PolarHBondContact O-N 2.82Å; A334-V337 PolarHBondContact O-N 2.83Å; A334-T338 PolarHBondContact O-N 3.47Å; A334-T338 PolarHBondContact O-OG1 3.32Å; A334-T338 VanDerWaalsContact O-OG1 3.08Å; A334-L770 HydrophobicContact CB-CD1 3.4Å; A334-L770 HydrophobicContact CB-CD2 4.43Å
335E97.2Very high94.2Very high8 Ų814.5 Ų14.54%0.0379%0.085CC..Hα-helixtrans-65-34.4175.3-175.663.5-155.900111.6G18 R19 R331 M332 V337 T338 A339 I352 V359 R361G18-E335 VanDerWaalsContact CA-OE1 3.31Å; G18-E335 WeakPolarHBondContact CA-OE1 3.48Å; R19-E335 PolarHBondContact N-OE1 2.92Å; R19-E335 PolarHBondContact N-OE2 3.06Å; R331-E335 PolarHBondContact O-N 3.3Å; M332-E335 PolarHBondContact O-N 2.95Å; E335-V337 VanDerWaalsContact C-N 3.32Å; E335-V337 PolarHBondContact O-N 2.78Å; E335-T338 PolarHBondContact O-N 3.31Å; E335-A339 VanDerWaalsContact O-CB 3.29Å; E335-A339 WeakPolarHBondContact O-CB 3.36Å; E335-A339 PolarHBondContact O-N 3.15Å; E335-I352 HydrophobicContact CB-CG2 4Å; E335-I352 HydrophobicContact CG-CD1 3.99Å; E335-I352 HydrophobicContact CG-CG1 4.48Å; E335-I352 HydrophobicContact CG-CG2 3.97Å; E335-V359 HydrophobicContact CB-CG1 3.89Å; E335-V359 HydrophobicContact CG-CG1 3.73Å; E335-R361 IonicContact OE1-CZ 3.07Å; E335-R361 IonicContact OE1-NE 2.71Å; E335-R361 PolarHBondContact OE1-NE 3.35Å; E335-R361 IonicContact OE1-NH2 2.61Å; E335-R361 PolarHBondContact OE1-NH2 3.31Å
336A97.4Very high93.3Very high0 Ų020.7 Ų20.70%012%0.118CC..Hα-helixtrans-61.2-40.4178.500000112.7V130 V175 L177 M332 G333 A334 A339 L340 I352V130-A336 HydrophobicContact CG1-CB 4.24Å; V130-A336 HydrophobicContact CG2-CB 4.4Å; V175-A336 HydrophobicContact CB-CB 4.4Å; V175-A336 HydrophobicContact CG1-CB 3.69Å; L177-A336 HydrophobicContact CD1-CB 4.37Å; L177-A336 HydrophobicContact CD2-CB 3.97Å; L177-A336 HydrophobicContact CG-CB 4.35Å; M332-A336 WeakPolarHBondContact O-CB 3.47Å; M332-A336 PolarHBondContact O-N 2.96Å; G333-A336 PolarHBondContact O-N 3.3Å; A334-A336 VanDerWaalsContact C-N 3.29Å; A334-A336 PolarHBondContact O-N 2.82Å; A336-A339 PolarHBondContact O-N 2.93Å; A336-L340 WeakPolarHBondContact O-CG 3.3Å; A336-L340 PolarHBondContact O-N 3.08Å; A336-I352 HydrophobicContact CB-CG1 4.02Å
337V97Very high92.6Very high0 Ų021.9 Ų21.90%013%0.129CC..Hα-helixtrans-64.3-49.6174.5176.70000110.2I34 V53 M56 M60 G333 A334 E335 A339 L340 M341I34-V337 HydrophobicContact CD1-CG1 3.92Å; I34-V337 HydrophobicContact CD1-CG2 4.35Å; V53-V337 HydrophobicContact CB-CG2 4.29Å; V53-V337 HydrophobicContact CG1-CG2 3.98Å; V53-V337 WeakPolarHBondContact O-CG2 3.38Å; M56-V337 HydrophobicContact CB-CB 4.15Å; M56-V337 HydrophobicContact CB-CG1 4.4Å; M56-V337 HydrophobicContact CB-CG2 4.08Å; M56-V337 HydrophobicContact CG-CB 3.78Å; M56-V337 HydrophobicContact CG-CG1 3.9Å; M56-V337 HydrophobicContact CG-CG2 4.28Å; M60-V337 HydrophobicContact SD-CG1 3.75Å; G333-V337 PolarHBondContact O-N 3.19Å; A334-V337 PolarHBondContact O-N 2.83Å; E335-V337 VanDerWaalsContact C-N 3.32Å; E335-V337 PolarHBondContact O-N 2.78Å; V337-A339 PolarHBondContact O-N 3.39Å; V337-L340 PolarHBondContact O-N 3.37Å; V337-L340 VanDerWaalsContact O-N 3.12Å; V337-M341 HydrophobicContact CG1-CG 4.48Å; V337-M341 WeakPolarHBondContact O-CG 3.31Å; V337-M341 PolarHBondContact O-N 3.35Å
338T95Very high92Very high8 Ų825.6 Ų25.65%0.04915%0.146CC..Hα-helixtrans-58.4-40.7179-50.30000110.9R19 A334 E335 M341 D342R19-T338 HydrophobicContact CB-CG2 4.28Å; R19-T338 HydrophobicContact CG-CG2 4.42Å; A334-T338 PolarHBondContact O-N 3.47Å; A334-T338 PolarHBondContact O-OG1 3.32Å; A334-T338 VanDerWaalsContact O-OG1 3.08Å; E335-T338 PolarHBondContact O-N 3.31Å; T338-M341 PolarHBondContact O-N 2.77Å; T338-D342 WeakPolarHBondContact O-CB 3.46Å; T338-D342 PolarHBondContact O-N 2.76Å
339A95Very high91.7Very high0 Ų025.8 Ų25.80%015%0.147CC..Hα-helixtrans-62.6-46.4175.100000112.3V175 E335 A336 V337 M341 D342 T343 I352V175-A339 HydrophobicContact CG2-CB 3.98Å; E335-A339 VanDerWaalsContact O-CB 3.29Å; E335-A339 WeakPolarHBondContact O-CB 3.36Å; E335-A339 PolarHBondContact O-N 3.15Å; A336-A339 PolarHBondContact O-N 2.93Å; V337-A339 PolarHBondContact O-N 3.39Å; A339-M341 VanDerWaalsContact C-N 3.3Å; A339-M341 PolarHBondContact O-N 2.85Å; A339-D342 PolarHBondContact O-N 2.95Å; A339-T343 WeakPolarHBondContact O-CB 3.31Å; A339-T343 PolarHBondContact O-N 2.78Å; A339-T343 PolarHBondContact O-OG1 3.3Å; A339-I352 HydrophobicContact CB-CD1 4Å
340L94.7Very high91.6Very high0 Ų026.4 Ų26.40%015%0.152CC..Hα-helixtrans-58.5-41.9176.8-77.2169.9000112.5I34 N128 V130 K173 V175 A336 V337I34-L340 HydrophobicContact CG2-CD1 4.2Å; N128-L340 HydrophobicContact CB-CD1 4.1Å; N128-L340 HydrophobicContact CB-CD2 4.17Å; V130-L340 HydrophobicContact CG2-CD1 3.41Å; V130-L340 VanDerWaalsContact CG2-CD1 3.41Å; K173-L340 HydrophobicContact CB-CD2 3.7Å; K173-L340 WeakPolarHBondContact CD-O 3.47Å; K173-L340 PolarHBondContact NZ-O 3.34Å; V175-L340 HydrophobicContact CB-CD2 4.26Å; V175-L340 HydrophobicContact CB-CG 4.15Å; V175-L340 HydrophobicContact CG2-CD2 3.67Å; V175-L340 HydrophobicContact CG2-CG 3.63Å; A336-L340 WeakPolarHBondContact O-CG 3.3Å; A336-L340 PolarHBondContact O-N 3.08Å; V337-L340 PolarHBondContact O-N 3.37Å; V337-L340 VanDerWaalsContact O-N 3.12Å
341M93.3Very high91.5Very high23 Ų2326.4 Ų26.411%0.11315%0.152CC..Hα-helixtrans-73-37.2-177.8-59.6-54103.900112.1N29 D32 I34 M60 N128 V337 T338 A339N29-M341 HydrophobicContact CB-CG 4.35Å; N29-M341 HydrophobicContact CB-SD 3.81Å; N29-M341 PolarHBondContact ND2-SD 2.98Å; N29-M341 VanDerWaalsContact ND2-SD 3.43Å; D32-M341 HydrophobicContact CB-SD 4.06Å; I34-M341 HydrophobicContact CD1-CE 3.9Å; I34-M341 HydrophobicContact CG1-CE 4.02Å; M60-M341 HydrophobicContact CE-CB 4Å; M60-M341 HydrophobicContact CE-CG 3.81Å; M60-M341 HydrophobicContact SD-CG 4.31Å; N128-M341 HydrophobicContact CB-CE 4.41Å; V337-M341 HydrophobicContact CG1-CG 4.48Å; V337-M341 WeakPolarHBondContact O-CG 3.31Å; V337-M341 PolarHBondContact O-N 3.35Å; T338-M341 PolarHBondContact O-N 2.77Å; A339-M341 VanDerWaalsContact C-N 3.3Å; A339-M341 PolarHBondContact O-N 2.85Å
342D89.4Confident91.5Very high40 Ų4025.6 Ų25.621%0.21415%0.149CC..Hα-helixtrans-78.6-18.5179.8-72.1-30.6000114.5R19 T338 A339 R361R19-D342 IonicContact CZ-OD1 3.96Å; R19-D342 IonicContact CZ-OD2 3.5Å; R19-D342 IonicContact NE-OD2 3.74Å; R19-D342 PolarHBondContact NE-OD2 3.18Å; R19-D342 IonicContact NH1-OD1 3.47Å; R19-D342 PolarHBondContact NH1-OD1 2.72Å; R19-D342 IonicContact NH1-OD2 3.9Å; R19-D342 PolarHBondContact NH1-OD2 2.81Å; R19-D342 IonicContact NH2-OD1 3.26Å; R19-D342 IonicContact NH2-OD2 2.99Å; T338-D342 WeakPolarHBondContact O-CB 3.46Å; T338-D342 PolarHBondContact O-N 2.76Å; A339-D342 PolarHBondContact O-N 2.95Å; D342-R361 IonicContact OD2-CZ 3.77Å; D342-R361 IonicContact OD2-NH1 2.99Å; D342-R361 PolarHBondContact OD2-NH1 3.47Å; D342-R361 IonicContact OD2-NH2 3.98Å; D342-R361 PolarHBondContact OD2-NH2 3.46Å
343T85.6Confident91.3Very high27 Ų2725.4 Ų25.417%0.16615%0.148CC..SBendtrans-85126.3-168.6-65.20000110.3K173 A339 A347K173-T343 WeakPolarHBondContact CE-O 3.38Å; K173-T343 PolarHBondContact NZ-O 3.03Å; A339-T343 WeakPolarHBondContact O-CB 3.31Å; A339-T343 PolarHBondContact O-N 2.78Å; A339-T343 PolarHBondContact O-OG1 3.3Å; T343-A347 HydrophobicContact CG2-CB 3.46Å; T343-A347 VanDerWaalsContact CG2-CB 3.46Å
344P84.9Confident91.1Very high77 Ų7725.8 Ų25.850%0.515%0.15SC..  trans-59.3152.5173.6-21.731.6000111.7N346 A347P344-N346 PolarHBondContact O-N 2.8Å; P344-N346 VanDerWaalsContact O-N 3.08Å; P344-A347 HydrophobicContact CB-CB 4.44Å; P344-A347 WeakPolarHBondContact O-CB 3.24Å; P344-A347 PolarHBondContact O-N 2.77Å; P344-A347 VanDerWaalsContact O-N 3.12Å
345P75.9Confident90.6Very high70 Ų7027 Ų2746%0.45516%0.155SC..THydrogen-bonded Turntrans-55.3-32.5-176.5-26.234.1000115
346N79Confident89.9Confident130 Ų13027.7 Ų27.770%0.69516%0.164SC*.THydrogen-bonded Turntrans-98.50.8-174.6-62.4-6.6000113.5N171 P344N171-N346 PolarHBondContact ND2-OD1 3.4Å; P344-N346 PolarHBondContact O-N 2.8Å; P344-N346 VanDerWaalsContact O-N 3.08Å
347A82.9Confident89.3Confident33 Ų3329.6 Ų29.627%0.27318%0.184SC..SBendtrans-68.5154.8-178.800000111.5R145 T343 P344R145-A347 PolarHBondContact NH1-O 3.42Å; T343-A347 HydrophobicContact CG2-CB 3.46Å; T343-A347 VanDerWaalsContact CG2-CB 3.46Å; P344-A347 HydrophobicContact CB-CB 4.44Å; P344-A347 WeakPolarHBondContact O-CB 3.24Å; P344-A347 PolarHBondContact O-N 2.77Å; P344-A347 VanDerWaalsContact O-N 3.12Å
348E85.4Confident88.8Confident95 Ų9531.5 Ų31.544%0.44420%0.195SC..PPolyproline II helixtrans-63.7143.1174.4-168-174.8163.700110.5A365E348-A365 WeakPolarHBondContact OE1-CB 3.46Å; E348-A365 PolarHBondContact OE1-N 2.91Å
349P90.4Very high88.8Confident5 Ų531.1 Ų31.13%0.03219%0.193CC..PPolyproline II helixtrans-59.4144.5172.9-24.337.9000110.7R145 I174 L364R145-P349 VanDerWaalsContact NE-CG 3.33Å; I174-P349 HydrophobicContact CB-CB 4.49Å; P349-L364 HydrophobicContact CB-CB 4.03Å; P349-L364 HydrophobicContact CB-CD2 3.83Å; P349-L364 WeakPolarHBondContact O-CB 3.09Å; P349-L364 PolarHBondContact O-N 3.28Å
350C93.9Very high88.7Confident14 Ų1431.1 Ų31.110%0.09519%0.193CC..EExtended strand (participates in β ladder)trans-115.2154.817468.50000111.3V175 G176 R361 V362V175-C350 WeakPolarHBondContact CA-O 3.16Å; G176-C350 PolarHBondContact N-O 3.31Å; C350-R361 HydrophobicContact CB-CB 4.26Å; C350-V362 CarbonylContact C-O 3.58Å; C350-V362 VanDerWaalsContact CA-O 3.22Å; C350-V362 WeakPolarHBondContact CA-O 3.43Å; C350-V362 WeakPolarHBondContact CB-O 3.48Å
351V95.7Very high88.7Confident0 Ų031.8 Ų31.80%020%0.195CC..EExtended strand (participates in β ladder)trans-103.7136.2165.2177.50000107.3L138 G176 V178 F185 V362 L364L138-V351 HydrophobicContact CD1-CG2 4.21Å; G176-V351 CarbonylContact O-C 3.47Å; G176-V351 VanDerWaalsContact O-CA 3.31Å; G176-V351 WeakPolarHBondContact O-CA 3.34Å; V178-V351 HydrophobicContact CG2-CG1 3.59Å; F185-V351 HydrophobicContact CE1-CG1 4.02Å; F185-V351 HydrophobicContact CE1-CG2 4.3Å; F185-V351 HydrophobicContact CZ-CG2 4.1Å; V351-V362 HydrophobicContact CB-CG2 4.28Å; V351-V362 PolarHBondContact N-O 3.38Å; V351-V362 WeakPolarHBondContact O-CG2 3.34Å; V351-V362 PolarHBondContact O-N 3.08Å; V351-L364 HydrophobicContact CG2-CB 4.02Å; V351-L364 HydrophobicContact CG2-CD1 3.35Å; V351-L364 HydrophobicContact CG2-CG 4.22Å
352I96.9Very high88.7Confident0 Ų031.3 Ų31.30%019%0.194CC..EExtended strand (participates in β ladder)trans-83.8121.3169.3-48.1-52.8000107.8V175 G176 L177 M332 E335 A336 A339 V359 V360 R361V175-I352 HydrophobicContact CG1-CD1 3.77Å; V175-I352 HydrophobicContact CG1-CG1 3.58Å; G176-I352 PolarHBondContact O-N 2.98Å; L177-I352 HydrophobicContact CD2-CB 3.54Å; L177-I352 HydrophobicContact CD2-CG1 3.67Å; L177-I352 HydrophobicContact CD2-CG2 4.45Å; M332-I352 HydrophobicContact CB-CB 4.48Å; M332-I352 HydrophobicContact CB-CG2 4.03Å; M332-I352 HydrophobicContact CG-CG2 3.94Å; E335-I352 HydrophobicContact CB-CG2 4Å; E335-I352 HydrophobicContact CG-CD1 3.99Å; E335-I352 HydrophobicContact CG-CG1 4.48Å; E335-I352 HydrophobicContact CG-CG2 3.97Å; A336-I352 HydrophobicContact CB-CG1 4.02Å; A339-I352 HydrophobicContact CB-CD1 4Å; I352-V359 HydrophobicContact CG2-CG1 3.37Å; I352-V360 WeakPolarHBondContact CA-O 3.25Å; I352-R361 HydrophobicContact CD1-CG 3.95Å
353A94.3Very high88.8Confident0 Ų030.9 Ų30.90%019%0.193CC..EExtended strand (participates in β ladder)trans-124.1170.2-177.500000110.8G187 M332 V359 V360 V362G187-A353 WeakPolarHBondContact O-CB 3.38Å; M332-A353 VanDerWaalsContact CE-C 3.41Å; A353-V359 WeakPolarHBondContact O-CA 3.33Å; A353-V360 HydrophobicContact CB-CG2 3.95Å; A353-V360 PolarHBondContact N-O 3.01Å; A353-V360 PolarHBondContact O-N 3.16Å; A353-V362 HydrophobicContact CB-CG2 3.47Å; A353-V362 VanDerWaalsContact CB-CG2 3.47Å
354I91.8Very high89.1Confident7 Ų729.6 Ų29.64%0.03619%0.185CC..EExtended strand (participates in β ladder)trans-116.8128.3169.8-168.5165.1000109.6T188 D189 M190 L328 M332 T358T188-I354 PolarHBondContact OG1-N 2.94Å; T188-I354 VanDerWaalsContact OG1-N 3.15Å; D189-I354 HydrophobicContact CB-CG2 4.44Å; D189-I354 WeakPolarHBondContact CB-O 3.27Å; D189-I354 PolarHBondContact N-O 2.85Å; M190-I354 HydrophobicContact CB-CG2 4.23Å; L328-I354 HydrophobicContact CD1-CB 3.95Å; L328-I354 HydrophobicContact CD1-CD1 3.71Å; L328-I354 HydrophobicContact CD1-CG1 4.44Å; L328-I354 HydrophobicContact CD1-CG2 3.88Å; M332-I354 HydrophobicContact CE-CB 4Å; M332-I354 HydrophobicContact CE-CG2 4.16Å; I354-T358 WeakPolarHBondContact CA-O 3.5Å
355H88.1Confident89.2Confident31 Ų3127.9 Ų27.914%0.14418%0.178CC..EExtended strand (participates in β ladder)trans-126.4119171.7-68.8161.8000109.7G187 D189 G357 T358 V360G187-H355 PolarHBondContact O-NE2 2.67Å; D189-H355 IonicContact OD1-CD2 3.7Å; D189-H355 VanDerWaalsContact OD2-CA 3.26Å; D189-H355 WeakPolarHBondContact OD2-CA 3.49Å; H355-G357 VanDerWaalsContact C-N 3.33Å; H355-G357 PolarHBondContact O-N 3.37Å; H355-T358 PolarHBondContact N-O 3.2Å; H355-T358 PolarHBondContact O-N 3.38Å; H355-V360 HydrophobicContact CB-CG1 4.46Å; H355-V360 HydrophobicContact CB-CG2 4.39Å
356G81.7Confident89.8Confident22 Ų2228 Ų2823%0.22717%0.171CC..THydrogen-bonded Turntrans50.252-179.500000112.5D189 T358 E737D189-G356 PolarHBondContact OD2-N 3.48Å; G356-T358 PolarHBondContact O-N 2.7Å; G356-E737 CarbonylContact C-O 3.53Å
357G83.8Confident90.2Very high40 Ų4022 Ų2241%0.41214%0.139SC..THydrogen-bonded Turntrans72.1-3.7178.700000115.9R331 H355R331-G357 PolarHBondContact NH1-O 2.88Å; R331-G357 PolarHBondContact NH2-O 3.3Å; H355-G357 VanDerWaalsContact C-N 3.33Å; H355-G357 PolarHBondContact O-N 3.37Å
358T88.2Confident90.4Very high39 Ų3921.4 Ų21.424%0.23913%0.132CC..EExtended strand (participates in β ladder)trans-108.4137.8-178.6-58.30000111.3L17 I354 H355 G356L17-T358 HydrophobicContact CD2-CG2 4.04Å; I354-T358 WeakPolarHBondContact CA-O 3.5Å; H355-T358 PolarHBondContact N-O 3.2Å; H355-T358 PolarHBondContact O-N 3.38Å; G356-T358 PolarHBondContact O-N 2.7Å
359V93.1Very high90.5Very high0 Ų022.2 Ų22.20%014%0.136CC..EExtended strand (participates in β ladder)trans-74.8134.3176.1177.80000110.5G18 E20 R331 E335 I352 A353G18-V359 WeakPolarHBondContact CA-O 3.46Å; G18-V359 PolarHBondContact N-O 3.49Å; E20-V359 HydrophobicContact CG-CB 4.2Å; E20-V359 HydrophobicContact CG-CG2 4.37Å; E20-V359 VanDerWaalsContact OE1-CG2 3.23Å; E20-V359 WeakPolarHBondContact OE1-CG2 3.32Å; R331-V359 HydrophobicContact CB-CG2 4Å; E335-V359 HydrophobicContact CB-CG1 3.89Å; E335-V359 HydrophobicContact CG-CG1 3.73Å; I352-V359 HydrophobicContact CG2-CG1 3.37Å; A353-V359 WeakPolarHBondContact O-CA 3.33Å
360V93.6Very high90.5Very high0 Ų027.2 Ų27.20%015%0.154CC..EExtended strand (participates in β ladder)trans-134.9157.7179.4-60.70000111L16 L17 I352 A353 H355L16-V360 CarbonylContact O-C 3.54Å; L16-V360 WeakPolarHBondContact O-CA 3.33Å; L16-V360 WeakPolarHBondContact O-CB 3.28Å; L17-V360 HydrophobicContact CD2-CG1 4.41Å; I352-V360 WeakPolarHBondContact CA-O 3.25Å; A353-V360 HydrophobicContact CB-CG2 3.95Å; A353-V360 PolarHBondContact N-O 3.01Å; A353-V360 PolarHBondContact O-N 3.16Å; H355-V360 HydrophobicContact CB-CG1 4.46Å; H355-V360 HydrophobicContact CB-CG2 4.39Å
361R94.9Very high90.3Very high14 Ų1426.8 Ų26.85%0.05315%0.151CC..EExtended strand (participates in β ladder)trans-103.4120.9171.2-47.7-178.5-173176.11.5108.5S15 L16 E335 D342 C350 I352S15-R361 WeakPolarHBondContact CA-O 3.44Å; L16-R361 HydrophobicContact CB-CB 4.32Å; L16-R361 PolarHBondContact N-O 2.96Å; L16-R361 PolarHBondContact O-N 3.18Å; E335-R361 IonicContact OE1-CZ 3.07Å; E335-R361 IonicContact OE1-NE 2.71Å; E335-R361 PolarHBondContact OE1-NE 3.35Å; E335-R361 IonicContact OE1-NH2 2.61Å; E335-R361 PolarHBondContact OE1-NH2 3.31Å; D342-R361 IonicContact OD2-CZ 3.77Å; D342-R361 IonicContact OD2-NH1 2.99Å; D342-R361 PolarHBondContact OD2-NH1 3.47Å; D342-R361 IonicContact OD2-NH2 3.98Å; D342-R361 PolarHBondContact OD2-NH2 3.46Å; C350-R361 HydrophobicContact CB-CB 4.26Å; I352-R361 HydrophobicContact CD1-CG 3.95Å
362V93.1Very high89.9Confident14 Ų1430.5 Ų30.59%0.08517%0.171CC..EExtended strand (participates in β ladder)trans-115.4141.5178.5-100.40000110.5C350 V351 A353 L364C350-V362 CarbonylContact C-O 3.58Å; C350-V362 VanDerWaalsContact CA-O 3.22Å; C350-V362 WeakPolarHBondContact CA-O 3.43Å; C350-V362 WeakPolarHBondContact CB-O 3.48Å; V351-V362 HydrophobicContact CB-CG2 4.28Å; V351-V362 PolarHBondContact N-O 3.38Å; V351-V362 WeakPolarHBondContact O-CG2 3.34Å; V351-V362 PolarHBondContact O-N 3.08Å; A353-V362 HydrophobicContact CB-CG2 3.47Å; A353-V362 VanDerWaalsContact CB-CG2 3.47Å; V362-L364 PolarHBondContact O-N 2.95Å
363P92.7Very high89.8Confident30 Ų3034.2 Ų34.220%0.19519%0.188CC..EExtended strand (participates in β ladder)trans-60.3129175.9-23.133.6000111.9A365 K366 C367P363-A365 PolarHBondContact O-N 2.88Å; P363-K366 HydrophobicContact CB-CB 4.24Å; P363-K366 PolarHBondContact O-N 3.29Å; P363-C367 PolarHBondContact O-N 3.48Å
364L90Very high89.7Confident0 Ų034.4 Ų34.40%019%0.189CC..Hα-helixtrans-62.9-43-175.4173.857.3000112L138 N142 F185 P349 V351 V362 K366 C367 V368L138-L364 HydrophobicContact CB-CD1 3.84Å; N142-L364 HydrophobicContact CB-CD2 3.71Å; N142-L364 HydrophobicContact CB-CG 4.37Å; F185-L364 HydrophobicContact CZ-CD1 4.46Å; P349-L364 HydrophobicContact CB-CB 4.03Å; P349-L364 HydrophobicContact CB-CD2 3.83Å; P349-L364 WeakPolarHBondContact O-CB 3.09Å; P349-L364 PolarHBondContact O-N 3.28Å; V351-L364 HydrophobicContact CG2-CB 4.02Å; V351-L364 HydrophobicContact CG2-CD1 3.35Å; V351-L364 HydrophobicContact CG2-CG 4.22Å; V362-L364 PolarHBondContact O-N 2.95Å; L364-K366 VanDerWaalsContact C-N 3.31Å; L364-K366 PolarHBondContact O-N 3.44Å; L364-C367 PolarHBondContact O-N 3.04Å; L364-V368 HydrophobicContact CD1-CG2 3.94Å; L364-V368 WeakPolarHBondContact O-CG2 3.47Å; L364-V368 PolarHBondContact O-N 3.3Å; L364-V368 VanDerWaalsContact O-N 3.09Å
365A87.1Confident89.7Confident42 Ų4238.8 Ų38.835%0.34721%0.208SC..Hα-helixtrans-62.7-41.2-176.600000111.4E348 P363 C367 V368 E369E348-A365 WeakPolarHBondContact OE1-CB 3.46Å; E348-A365 PolarHBondContact OE1-N 2.91Å; P363-A365 PolarHBondContact O-N 2.88Å; A365-C367 PolarHBondContact O-N 3.45Å; A365-V368 PolarHBondContact O-N 3.32Å; A365-E369 WeakPolarHBondContact O-CB 3.34Å; A365-E369 PolarHBondContact O-N 3.38Å
366K88.9Confident90.1Very high72 Ų7243.3 Ų43.331%0.31323%0.227SC..Hα-helixtrans-64.1-38178.6-171.2172.9-175170.20112.9G13 P363 L364 R370G13-K366 PolarHBondContact O-NZ 3.2Å; P363-K366 HydrophobicContact CB-CB 4.24Å; P363-K366 PolarHBondContact O-N 3.29Å; L364-K366 VanDerWaalsContact C-N 3.31Å; L364-K366 PolarHBondContact O-N 3.44Å; K366-R370 WeakPolarHBondContact O-CG 3.3Å; K366-R370 PolarHBondContact O-N 3.46Å; K366-R370 VanDerWaalsContact O-N 3.12Å
367C88.6Confident90.7Very high4 Ų442.5 Ų42.53%0.02722%0.218CC..Hα-helixtrans-66.7-44175.8-74.40000112.1F185 C186 P363 L364 A365 R370 T371F185-C367 HydrophobicContact CD1-CB 4.44Å; F185-C367 HydrophobicContact CE1-CB 3.44Å; F185-C367 VanDerWaalsContact CE1-CB 3.44Å; F185-C367 HydrophobicContact CE2-CB 4.4Å; F185-C367 HydrophobicContact CZ-CB 3.41Å; F185-C367 VanDerWaalsContact CZ-CB 3.41Å; C186-C367 WeakPolarHBondContact O-CA 3.34Å; C186-C367 VanDerWaalsContact O-CB 3.23Å; C186-C367 WeakPolarHBondContact O-CB 3.35Å; C186-C367 PolarHBondContact O-SG 3.41Å; P363-C367 PolarHBondContact O-N 3.48Å; L364-C367 PolarHBondContact O-N 3.04Å; A365-C367 PolarHBondContact O-N 3.45Å; C367-R370 PolarHBondContact O-N 2.83Å; C367-T371 WeakPolarHBondContact O-CB 3.47Å; C367-T371 PolarHBondContact O-N 2.92Å; C367-T371 PolarHBondContact O-OG1 3.18Å
368V85.4Confident91.2Very high20 Ų2042 Ų4212%0.12121%0.206CC..Hα-helixtrans-64.3-44.1177.2174.10000110.7T139 L364 A365 R370 T371 N372T139-V368 HydrophobicContact CG2-CG1 4.45Å; L364-V368 HydrophobicContact CD1-CG2 3.94Å; L364-V368 WeakPolarHBondContact O-CG2 3.47Å; L364-V368 PolarHBondContact O-N 3.3Å; L364-V368 VanDerWaalsContact O-N 3.09Å; A365-V368 PolarHBondContact O-N 3.32Å; V368-R370 PolarHBondContact O-N 2.93Å; V368-T371 PolarHBondContact O-N 3.23Å; V368-N372 PolarHBondContact O-N 3.1Å; V368-N372 PolarHBondContact O-ND2 2.73Å
369E89.2Confident91.4Very high112 Ų11244 Ų4452%0.52323%0.226SC..Hα-helixtrans-57.1-50.9177-171.9-169.4171.700111.7A365 T371 N372 Q373A365-E369 WeakPolarHBondContact O-CB 3.34Å; A365-E369 PolarHBondContact O-N 3.38Å; E369-T371 VanDerWaalsContact C-N 3.31Å; E369-T371 PolarHBondContact O-N 2.8Å; E369-N372 PolarHBondContact O-N 2.72Å; E369-N372 VanDerWaalsContact O-N 3.15Å; E369-Q373 WeakPolarHBondContact O-CG 3.33Å; E369-Q373 PolarHBondContact O-N 3.36Å; E369-Q373 PolarHBondContact OE1-NE2 3.26Å
370R89.6Confident91.6Very high111 Ų11149.8 Ų49.842%0.41925%0.253SS..Hα-helixtrans-61-39.4177.4-74.6177.5173.3-171.5-4.5112.6C186 K366 C367 V368 N372 Q373 V374C186-R370 HydrophobicContact CB-CB 3.6Å; K366-R370 WeakPolarHBondContact O-CG 3.3Å; K366-R370 PolarHBondContact O-N 3.46Å; K366-R370 VanDerWaalsContact O-N 3.12Å; C367-R370 PolarHBondContact O-N 2.83Å; V368-R370 PolarHBondContact O-N 2.93Å; R370-N372 VanDerWaalsContact C-N 3.3Å; R370-N372 PolarHBondContact O-N 2.97Å; R370-Q373 WeakPolarHBondContact O-CB 3.47Å; R370-Q373 PolarHBondContact O-N 3.19Å; R370-V374 PolarHBondContact O-N 3.44Å; R370-V374 VanDerWaalsContact O-N 3.14Å
371T88.8Confident91.6Very high5 Ų555 Ų553%0.03128%0.276CS..Hα-helixtrans-64.1-38.4177.1-54.80000111.1C186 C367 V368 E369 V374 K375C186-T371 WeakPolarHBondContact CB-OG1 3.33Å; C186-T371 PolarHBondContact N-OG1 3.44Å; C367-T371 WeakPolarHBondContact O-CB 3.47Å; C367-T371 PolarHBondContact O-N 2.92Å; C367-T371 PolarHBondContact O-OG1 3.18Å; V368-T371 PolarHBondContact O-N 3.23Å; E369-T371 VanDerWaalsContact C-N 3.31Å; E369-T371 PolarHBondContact O-N 2.8Å; T371-V374 PolarHBondContact O-N 3.36Å; T371-K375 PolarHBondContact O-N 3.25Å
372N89Confident91.7Very high77 Ų7757.3 Ų57.341%0.41229%0.289SS..Hα-helixtrans-69.6-34.1174.2-70.9-23.9000112.7V368 E369 R370 V374 K375 K376V368-N372 PolarHBondContact O-N 3.1Å; V368-N372 PolarHBondContact O-ND2 2.73Å; E369-N372 PolarHBondContact O-N 2.72Å; E369-N372 VanDerWaalsContact O-N 3.15Å; R370-N372 VanDerWaalsContact C-N 3.3Å; R370-N372 PolarHBondContact O-N 2.97Å; N372-V374 VanDerWaalsContact C-N 3.28Å; N372-V374 PolarHBondContact O-N 3.42Å; N372-K375 PolarHBondContact O-N 2.93Å; N372-K376 PolarHBondContact O-N 3.31Å
373Q93.6Very high91.8Very high79 Ų7959 Ų5937%0.36929%0.294SS..Hα-helixtrans-61.5-36.5173.1-70.2170.3-0.600111.9E369 R370 K376 A377 L389E369-Q373 WeakPolarHBondContact O-CG 3.33Å; E369-Q373 PolarHBondContact O-N 3.36Å; E369-Q373 PolarHBondContact OE1-NE2 3.26Å; R370-Q373 WeakPolarHBondContact O-CB 3.47Å; R370-Q373 PolarHBondContact O-N 3.19Å; Q373-K376 PolarHBondContact O-N 3.48Å; Q373-A377 WeakPolarHBondContact O-CB 3.33Å; Q373-A377 PolarHBondContact O-N 2.9Å; Q373-L389 HydrophobicContact CB-CD1 3.8Å
374V92.8Very high91.8Very high3 Ų365 Ų652%0.01832%0.32CS..Hα-helixtrans-62.4-49172.8177.10000110.7R370 T371 N372 K376 A377 M378 L389R370-V374 PolarHBondContact O-N 3.44Å; R370-V374 VanDerWaalsContact O-N 3.14Å; T371-V374 PolarHBondContact O-N 3.36Å; N372-V374 VanDerWaalsContact C-N 3.28Å; N372-V374 PolarHBondContact O-N 3.42Å; V374-K376 PolarHBondContact O-N 3.1Å; V374-A377 PolarHBondContact O-N 3.42Å; V374-M378 HydrophobicContact CG1-CG 4.3Å; V374-M378 HydrophobicContact CG1-SD 3.91Å; V374-M378 WeakPolarHBondContact O-CG 3.27Å; V374-M378 PolarHBondContact O-N 2.87Å; V374-L389 HydrophobicContact CG2-CB 3.46Å; V374-L389 VanDerWaalsContact CG2-CB 3.46Å; V374-L389 HydrophobicContact CG2-CD1 3.98Å; V374-L389 HydrophobicContact CG2-CG 4.35Å
375K91.8Very high92.1Very high100 Ų10066.2 Ų66.244%0.43533%0.327SS..Hα-helixtrans-56.5-42.3178.5-66175.1-176.1170.70111.1D135 T371 N372 A379D135-K375 IonicContact OD2-NZ 3.98Å; D135-K375 PolarHBondContact OD2-NZ 3.27Å; T371-K375 PolarHBondContact O-N 3.25Å; N372-K375 PolarHBondContact O-N 2.93Å; K375-A379 WeakPolarHBondContact O-CB 3.36Å; K375-A379 PolarHBondContact O-N 2.86Å; K375-A379 VanDerWaalsContact O-N 3.08Å
376K95.7Very high92.5Very high126 Ų12664.2 Ų64.255%0.54831%0.311SS..Hα-helixtrans-63.3-51.6175.9-176.6179.8176.2-1760112N372 Q373 V374 M378 A379 E380N372-K376 PolarHBondContact O-N 3.31Å; Q373-K376 PolarHBondContact O-N 3.48Å; V374-K376 PolarHBondContact O-N 3.1Å; K376-M378 VanDerWaalsContact C-N 3.29Å; K376-M378 PolarHBondContact O-N 3.41Å; K376-A379 PolarHBondContact O-N 3.37Å; K376-A379 VanDerWaalsContact O-N 3.1Å; K376-E380 VanDerWaalsContact CE-CD 3.43Å; K376-E380 WeakPolarHBondContact CE-OE1 3.36Å; K376-E380 WeakPolarHBondContact CE-OE2 3.45Å; K376-E380 HydrophobicContact CG-CG 4.45Å; K376-E380 IonicContact NZ-OE1 3.75Å; K376-E380 WeakPolarHBondContact O-CG 3.38Å; K376-E380 PolarHBondContact O-N 3.24Å
377A95.8Very high92.7Very high5 Ų561.8 Ų61.84%0.04130%0.302CS..Hα-helixtrans-58.2-41.6-179.900000112Q373 V374 E380 K381 D382 T385 A386Q373-A377 WeakPolarHBondContact O-CB 3.33Å; Q373-A377 PolarHBondContact O-N 2.9Å; V374-A377 PolarHBondContact O-N 3.42Å; A377-E380 PolarHBondContact O-N 2.99Å; A377-K381 PolarHBondContact O-N 3.21Å; A377-K381 VanDerWaalsContact O-N 3.09Å; A377-D382 HydrophobicContact CB-CB 4.43Å; A377-D382 PolarHBondContact O-N 3.42Å; A377-T385 HydrophobicContact CB-CG2 4.01Å; A377-A386 HydrophobicContact CB-CB 4.19Å
378M93.5Very high93Very high29 Ų2968.3 Ų68.314%0.14333%0.326CS..Hα-helixtrans-64.6-41175.3-67.6-179.36900112.7H227 P247 V374 K376 E380 K381 W383 A386H227-M378 HydrophobicContact CB-CE 4.29Å; H227-M378 WeakPolarHBondContact O-CE 3.45Å; P247-M378 HydrophobicContact CB-CE 3.61Å; P247-M378 HydrophobicContact CG-CE 4.14Å; V374-M378 HydrophobicContact CG1-CG 4.3Å; V374-M378 HydrophobicContact CG1-SD 3.91Å; V374-M378 WeakPolarHBondContact O-CG 3.27Å; V374-M378 PolarHBondContact O-N 2.87Å; K376-M378 VanDerWaalsContact C-N 3.29Å; K376-M378 PolarHBondContact O-N 3.41Å; M378-E380 VanDerWaalsContact C-N 3.34Å; M378-K381 PolarHBondContact O-N 3.09Å; M378-W383 HydrophobicContact CB-CZ3 4.5Å; M378-A386 HydrophobicContact CG-CB 3.9Å
379A93.2Very high93.3Very high81 Ų8169.3 Ų69.367%0.66933%0.33SS*.Hα-helixtrans-66.6-35.8177.300000112.5K375 K376 K381K375-A379 WeakPolarHBondContact O-CB 3.36Å; K375-A379 PolarHBondContact O-N 2.86Å; K375-A379 VanDerWaalsContact O-N 3.08Å; K376-A379 PolarHBondContact O-N 3.37Å; K376-A379 VanDerWaalsContact O-N 3.1Å; A379-K381 VanDerWaalsContact C-N 3.25Å; A379-K381 PolarHBondContact O-N 3.46Å
380E96Very high93.4Very high122 Ų12266.1 Ų66.157%0.5731%0.314SS*.THydrogen-bonded Turntrans-81.5-1.2176.9-68.3174.9168.300113.1K376 A377 M378 D382K376-E380 VanDerWaalsContact CE-CD 3.43Å; K376-E380 WeakPolarHBondContact CE-OE1 3.36Å; K376-E380 WeakPolarHBondContact CE-OE2 3.45Å; K376-E380 HydrophobicContact CG-CG 4.45Å; K376-E380 IonicContact NZ-OE1 3.75Å; K376-E380 WeakPolarHBondContact O-CG 3.38Å; K376-E380 PolarHBondContact O-N 3.24Å; A377-E380 PolarHBondContact O-N 2.99Å; M378-E380 VanDerWaalsContact C-N 3.34Å; E380-D382 PolarHBondContact O-N 2.98Å
381K95Very high93.3Very high108 Ų10862 Ų6247%0.4731%0.305SS..THydrogen-bonded Turntrans61.924.2-176.9-47.2178.3-165.8-178.10113.6N286 A377 M378 A379 W383N286-K381 WeakPolarHBondContact O-CE 3.37Å; N286-K381 PolarHBondContact O-NZ 3.29Å; A377-K381 PolarHBondContact O-N 3.21Å; A377-K381 VanDerWaalsContact O-N 3.09Å; M378-K381 PolarHBondContact O-N 3.09Å; A379-K381 VanDerWaalsContact C-N 3.25Å; A379-K381 PolarHBondContact O-N 3.46Å; K381-W383 VanDerWaalsContact C-N 3.31Å; K381-W383 HydrophobicContact CB-CH2 4.25Å; K381-W383 HydrophobicContact CB-CZ2 3.57Å; K381-W383 HydrophobicContact CG-CH2 4.24Å; K381-W383 HydrophobicContact CG-CZ2 3.8Å; K381-W383 PolarHBondContact O-N 3.4Å; K381-W383 VanDerWaalsContact O-N 3.13Å; K381-W383 PolarHBondContact O-NE1 3.48Å
382D95.9Very high93.1Very high64 Ų6469.6 Ų69.634%0.34234%0.338SS..  trans-83.777.2169.5-176.7-2.6000109.8A377 E380 E384 T385 A386A377-D382 HydrophobicContact CB-CB 4.43Å; A377-D382 PolarHBondContact O-N 3.42Å; E380-D382 PolarHBondContact O-N 2.98Å; D382-E384 VanDerWaalsContact C-N 3.32Å; D382-E384 PolarHBondContact O-N 3.49Å; D382-T385 VanDerWaalsContact CG-OG1 3.26Å; D382-T385 PolarHBondContact O-N 3.22Å; D382-T385 WeakPolarHBondContact OD1-CB 3.42Å; D382-T385 PolarHBondContact OD1-N 2.97Å; D382-T385 PolarHBondContact OD1-OG1 3.36Å; D382-T385 WeakPolarHBondContact OD2-CB 3.45Å; D382-T385 PolarHBondContact OD2-OG1 3.04Å; D382-A386 PolarHBondContact O-N 2.78Å
383W94.5Very high92.8Very high49 Ų4968.1 Ų68.119%0.18633%0.332CS..Hα-helixtrans-64.4-34.8-176.3-47.5120.6000112.7P250 V283 M378 K381 A386 V387P250-W383 HydrophobicContact CG-CD2 3.6Å; P250-W383 HydrophobicContact CG-CE3 3.68Å; P250-W383 HydrophobicContact CG-CG 4.23Å; P250-W383 HydrophobicContact CG-CH2 3.95Å; P250-W383 HydrophobicContact CG-CZ2 3.86Å; P250-W383 HydrophobicContact CG-CZ3 3.86Å; V283-W383 HydrophobicContact CG2-CH2 4.07Å; V283-W383 HydrophobicContact CG2-CZ3 4.4Å; M378-W383 HydrophobicContact CB-CZ3 4.5Å; K381-W383 VanDerWaalsContact C-N 3.31Å; K381-W383 HydrophobicContact CB-CH2 4.25Å; K381-W383 HydrophobicContact CB-CZ2 3.57Å; K381-W383 HydrophobicContact CG-CH2 4.24Å; K381-W383 HydrophobicContact CG-CZ2 3.8Å; K381-W383 PolarHBondContact O-N 3.4Å; K381-W383 VanDerWaalsContact O-N 3.13Å; K381-W383 PolarHBondContact O-NE1 3.48Å; W383-A386 PolarHBondContact O-N 3.01Å; W383-V387 WeakPolarHBondContact O-CG2 3.21Å; W383-V387 PolarHBondContact O-N 3.12Å
384E94.5Very high92.7Very high156 Ų15664.7 Ų64.773%0.72932%0.315SS*.Hα-helixtrans-66.3-46-179.7-171.6179.7171.100111D382 A386 V387 R388D382-E384 VanDerWaalsContact C-N 3.32Å; D382-E384 PolarHBondContact O-N 3.49Å; E384-A386 VanDerWaalsContact C-N 3.34Å; E384-A386 PolarHBondContact O-N 2.79Å; E384-V387 PolarHBondContact O-N 2.94Å; E384-R388 WeakPolarHBondContact O-CB 3.36Å; E384-R388 PolarHBondContact O-N 2.91Å
385T95.4Very high92.7Very high26 Ų2666.8 Ų66.816%0.1633%0.326CS..Hα-helixtrans-64.6-39.3174-66.80000111.5A377 D382 V387 R388 L389A377-T385 HydrophobicContact CB-CG2 4.01Å; D382-T385 VanDerWaalsContact CG-OG1 3.26Å; D382-T385 PolarHBondContact O-N 3.22Å; D382-T385 WeakPolarHBondContact OD1-CB 3.42Å; D382-T385 PolarHBondContact OD1-N 2.97Å; D382-T385 PolarHBondContact OD1-OG1 3.36Å; D382-T385 WeakPolarHBondContact OD2-CB 3.45Å; D382-T385 PolarHBondContact OD2-OG1 3.04Å; T385-V387 PolarHBondContact O-N 3.46Å; T385-R388 PolarHBondContact O-N 3.06Å; T385-R388 PolarHBondContact OG1-NH2 2.78Å; T385-L389 HydrophobicContact CG2-CD1 3.67Å; T385-L389 HydrophobicContact CG2-CG 4.06Å; T385-L389 WeakPolarHBondContact O-CB 3.4Å; T385-L389 VanDerWaalsContact O-CG 3.25Å; T385-L389 WeakPolarHBondContact O-CG 3.35Å; T385-L389 PolarHBondContact O-N 2.91Å
386A94.7Very high92.4Very high0 Ų065.2 Ų65.20%032%0.318CS..Hα-helixtrans-58.4-48.7176.500000111.8A377 M378 D382 W383 E384 R388 L389 R390A377-A386 HydrophobicContact CB-CB 4.19Å; M378-A386 HydrophobicContact CG-CB 3.9Å; D382-A386 PolarHBondContact O-N 2.78Å; W383-A386 PolarHBondContact O-N 3.01Å; E384-A386 VanDerWaalsContact C-N 3.34Å; E384-A386 PolarHBondContact O-N 2.79Å; A386-R388 PolarHBondContact O-N 2.67Å; A386-L389 PolarHBondContact O-N 3.15Å; A386-R390 WeakPolarHBondContact O-CG 3.36Å; A386-R390 PolarHBondContact O-N 3.16Å
387V94.7Very high92.2Very high20 Ų2059.2 Ų59.212%0.12129%0.291CS..Hα-helixtrans-61.1-44.4175.6170.10000111.3E248 W383 E384 T385 L389 R390 F394 I395 L398E248-V387 HydrophobicContact CB-CG2 3.85Å; E248-V387 WeakPolarHBondContact O-CG2 3.27Å; W383-V387 WeakPolarHBondContact O-CG2 3.21Å; W383-V387 PolarHBondContact O-N 3.12Å; E384-V387 PolarHBondContact O-N 2.94Å; T385-V387 PolarHBondContact O-N 3.46Å; V387-L389 VanDerWaalsContact C-N 3.31Å; V387-L389 PolarHBondContact O-N 3.35Å; V387-R390 PolarHBondContact O-N 2.69Å; V387-F394 HydrophobicContact CG1-CD1 4.38Å; V387-I395 HydrophobicContact CG1-CG1 3.66Å; V387-L398 HydrophobicContact CG1-CD2 4.21Å; V387-L398 HydrophobicContact CG2-CD2 4.16Å
388R94.5Very high92.1Very high141 Ų14159.3 Ų59.353%0.53229%0.291SS..Hα-helixtrans-60.5-41.4179.1-173.4178.665-127.3-6.6112.1E384 T385 A386 G391E384-R388 WeakPolarHBondContact O-CB 3.36Å; E384-R388 PolarHBondContact O-N 2.91Å; T385-R388 PolarHBondContact O-N 3.06Å; T385-R388 PolarHBondContact OG1-NH2 2.78Å; A386-R388 PolarHBondContact O-N 2.67Å; R388-G391 PolarHBondContact O-N 3.16Å
389L92.1Very high91.8Very high42 Ų4263.5 Ų63.522%0.2231%0.31CS..Hα-helixtrans-70.5-29.8-179.3-73.4171.7000113.1Q373 V374 T385 A386 V387 G391Q373-L389 HydrophobicContact CB-CD1 3.8Å; V374-L389 HydrophobicContact CG2-CB 3.46Å; V374-L389 VanDerWaalsContact CG2-CB 3.46Å; V374-L389 HydrophobicContact CG2-CD1 3.98Å; V374-L389 HydrophobicContact CG2-CG 4.35Å; T385-L389 HydrophobicContact CG2-CD1 3.67Å; T385-L389 HydrophobicContact CG2-CG 4.06Å; T385-L389 WeakPolarHBondContact O-CB 3.4Å; T385-L389 VanDerWaalsContact O-CG 3.25Å; T385-L389 WeakPolarHBondContact O-CG 3.35Å; T385-L389 PolarHBondContact O-N 2.91Å; A386-L389 PolarHBondContact O-N 3.15Å; V387-L389 VanDerWaalsContact C-N 3.31Å; V387-L389 PolarHBondContact O-N 3.35Å; L389-G391 PolarHBondContact O-N 3.1Å
390R90.6Very high91.5Very high45 Ų4560.2 Ų60.217%0.1728%0.282CS..Hα-helixtrans-62-27170.8-68.9-63.6-170.6-157.4-3.7112.7D184 H227 E248 A386 V387 F394D184-R390 PolarHBondContact O-NH1 2.83Å; D184-R390 VanDerWaalsContact O-NH1 3.15Å; H227-R390 PolarHBondContact O-NH2 3.49Å; E248-R390 HydrophobicContact CG-CG 4.1Å; E248-R390 IonicContact OE1-CZ 2.65Å; E248-R390 IonicContact OE1-NE 2.93Å; E248-R390 PolarHBondContact OE1-NE 3.34Å; E248-R390 IonicContact OE1-NH2 3.81Å; E248-R390 PolarHBondContact OE1-NH2 3.18Å; E248-R390 VanDerWaalsContact OE1-NH2 3.13Å; A386-R390 WeakPolarHBondContact O-CG 3.36Å; A386-R390 PolarHBondContact O-N 3.16Å; V387-R390 PolarHBondContact O-N 2.69Å; R390-F394 HydrophobicContact CB-CB 3.67Å; R390-F394 HydrophobicContact CB-CD1 4.13Å; R390-F394 HydrophobicContact CB-CD2 3.9Å; R390-F394 HydrophobicContact CB-CG 3.64Å; R390-F394 HydrophobicContact CG-CD1 4.46Å; R390-F394 HydrophobicContact CG-CD2 4.08Å; R390-F394 HydrophobicContact CG-CE2 4.33Å; R390-F394 HydrophobicContact CG-CG 4.17Å
391G87.6Confident91.2Very high23 Ų2354.7 Ų54.724%0.23726%0.256CS..  trans103.4175.7171.300000114.9R388 L389 T393 F394 I395R388-G391 PolarHBondContact O-N 3.16Å; L389-G391 PolarHBondContact O-N 3.1Å; G391-T393 VanDerWaalsContact C-N 3.34Å; G391-T393 PolarHBondContact O-N 3.3Å; G391-F394 WeakPolarHBondContact O-CB 3.47Å; G391-F394 PolarHBondContact O-N 3.21Å; G391-F394 VanDerWaalsContact O-N 3.17Å; G391-I395 PolarHBondContact O-N 2.85Å; G391-I395 VanDerWaalsContact O-N 3.17Å
392K84.3Confident90.8Very high165 Ų16553.2 Ų53.272%0.71725%0.25SC*.Hα-helixtrans-60.7-38.7-168.6-64.3-175.2178.8-175.90113.5F394 I395 R396K392-F394 VanDerWaalsContact C-N 3.33Å; K392-F394 PolarHBondContact O-N 2.96Å; K392-I395 PolarHBondContact O-N 2.91Å; K392-R396 WeakPolarHBondContact O-CB 3.5Å; K392-R396 PolarHBondContact O-N 3.09Å
393T83.3Confident90.1Very high47 Ų4751.6 Ų51.629%0.28824%0.241SC..Hα-helixtrans-64.5-40.3179.6-54.70000111.4G391 R396 N397G391-T393 VanDerWaalsContact C-N 3.34Å; G391-T393 PolarHBondContact O-N 3.3Å; T393-R396 PolarHBondContact O-N 2.98Å; T393-N397 PolarHBondContact O-N 2.92Å; T393-N397 PolarHBondContact O-ND2 2.96Å
394F91.5Very high89.4Confident6 Ų649.6 Ų49.63%0.02623%0.234CC..Hα-helixtrans-64.1-49.5176.6-167.2-77.6000111Y230 L233 I246 E248 V387 R390 G391 K392 R396 N397 L398Y230-F394 AromaticContact CD2-CD2 3.99Å; Y230-F394 HydrophobicContact CD2-CD2 3.99Å; L233-F394 HydrophobicContact CD2-CD1 4.26Å; L233-F394 HydrophobicContact CD2-CD2 4.43Å; L233-F394 HydrophobicContact CD2-CE1 4.02Å; L233-F394 HydrophobicContact CD2-CE2 4.19Å; L233-F394 HydrophobicContact CD2-CG 4.45Å; L233-F394 HydrophobicContact CD2-CZ 3.97Å; I246-F394 HydrophobicContact CD1-CE1 4.31Å; I246-F394 HydrophobicContact CD1-CZ 4.09Å; E248-F394 HydrophobicContact CB-CE1 3.9Å; E248-F394 HydrophobicContact CB-CZ 3.87Å; E248-F394 HydrophobicContact CG-CE1 4.26Å; E248-F394 HydrophobicContact CG-CZ 3.89Å; V387-F394 HydrophobicContact CG1-CD1 4.38Å; R390-F394 HydrophobicContact CB-CB 3.67Å; R390-F394 HydrophobicContact CB-CD1 4.13Å; R390-F394 HydrophobicContact CB-CD2 3.9Å; R390-F394 HydrophobicContact CB-CG 3.64Å; R390-F394 HydrophobicContact CG-CD1 4.46Å; R390-F394 HydrophobicContact CG-CD2 4.08Å; R390-F394 HydrophobicContact CG-CE2 4.33Å; R390-F394 HydrophobicContact CG-CG 4.17Å; G391-F394 WeakPolarHBondContact O-CB 3.47Å; G391-F394 PolarHBondContact O-N 3.21Å; G391-F394 VanDerWaalsContact O-N 3.17Å; K392-F394 VanDerWaalsContact C-N 3.33Å; K392-F394 PolarHBondContact O-N 2.96Å; F394-R396 VanDerWaalsContact C-N 3.31Å; F394-R396 PolarHBondContact O-N 2.86Å; F394-N397 PolarHBondContact O-N 3.2Å; F394-L398 WeakPolarHBondContact O-CB 3.43Å; F394-L398 PolarHBondContact O-N 3.11Å
395I92Very high88.7Confident48 Ų4843.3 Ų43.325%0.24621%0.206CC..Hα-helixtrans-52.8-50.9176.7-68.7160.2000110.5V387 G391 K392 N397 L398 E399V387-I395 HydrophobicContact CG1-CG1 3.66Å; G391-I395 PolarHBondContact O-N 2.85Å; G391-I395 VanDerWaalsContact O-N 3.17Å; K392-I395 PolarHBondContact O-N 2.91Å; I395-N397 PolarHBondContact O-N 2.81Å; I395-L398 WeakPolarHBondContact O-CA 3.38Å; I395-L398 WeakPolarHBondContact O-CB 3.38Å; I395-L398 PolarHBondContact O-N 3.03Å; I395-E399 HydrophobicContact CG2-CG 4.31Å; I395-E399 WeakPolarHBondContact CG2-OE1 3.47Å; I395-E399 WeakPolarHBondContact O-CG 3.46Å; I395-E399 PolarHBondContact O-N 3.44Å
396R85.9Confident87.7Confident67 Ų6746.4 Ų46.425%0.25322%0.217SC..Hα-helixtrans-66.6-37.4-176.1-176.2160.5164.5173.9-10.4113.1K392 T393 F394 L398 T400 S740K392-R396 WeakPolarHBondContact O-CB 3.5Å; K392-R396 PolarHBondContact O-N 3.09Å; T393-R396 PolarHBondContact O-N 2.98Å; F394-R396 VanDerWaalsContact C-N 3.31Å; F394-R396 PolarHBondContact O-N 2.86Å; R396-L398 VanDerWaalsContact C-N 3.32Å; R396-T400 WeakPolarHBondContact O-CB 3.45Å; R396-T400 PolarHBondContact O-N 2.9Å; R396-T400 PolarHBondContact O-OG1 2.97Å; R396-S740 PolarHBondContact NH1-OG 3.27Å; R396-S740 PolarHBondContact NH2-OG 3.29Å
397N91Very high86.1Confident0 Ų047.6 Ų47.60%022%0.223CC..Hα-helixtrans-60.6-45.1170.7-84.4-37.1000110.6L233 L237 T393 F394 I395 E399 T400 Y401 N695 R699L233-N397 HydrophobicContact CD2-CB 3.69Å; L233-N397 HydrophobicContact CG-CB 4Å; L237-N397 HydrophobicContact CD1-CB 3.85Å; L237-N397 WeakPolarHBondContact CD1-OD1 3.46Å; T393-N397 PolarHBondContact O-N 2.92Å; T393-N397 PolarHBondContact O-ND2 2.96Å; F394-N397 PolarHBondContact O-N 3.2Å; I395-N397 PolarHBondContact O-N 2.81Å; N397-E399 PolarHBondContact O-N 2.92Å; N397-T400 PolarHBondContact O-N 3.03Å; N397-Y401 VanDerWaalsContact O-CB 3.25Å; N397-Y401 WeakPolarHBondContact O-CB 3.19Å; N397-Y401 PolarHBondContact O-N 2.8Å; N397-N695 PolarHBondContact OD1-ND2 3.39Å; N397-N695 PolarHBondContact OD1-OD1 2.81Å; N397-R699 WeakPolarHBondContact OD1-CD 3.27Å
398L93Very high84.8Confident6 Ų653.3 Ų53.33%0.03124%0.243CC..Hα-helixtrans-63.6-43-179.6-177.859.1000112.2L233 I246 W249 V387 F394 I395 R396 Y401 K402L233-L398 HydrophobicContact CD1-CD1 4.27Å; L233-L398 HydrophobicContact CD2-CB 4.13Å; I246-L398 HydrophobicContact CD1-CD1 3.89Å; W249-L398 HydrophobicContact CB-CD1 4.14Å; W249-L398 HydrophobicContact CB-CD2 3.95Å; W249-L398 HydrophobicContact CD2-CD1 4.06Å; W249-L398 HydrophobicContact CE3-CD1 3.83Å; W249-L398 HydrophobicContact CG-CD1 4.2Å; W249-L398 HydrophobicContact CG-CD2 4.17Å; V387-L398 HydrophobicContact CG1-CD2 4.21Å; V387-L398 HydrophobicContact CG2-CD2 4.16Å; F394-L398 WeakPolarHBondContact O-CB 3.43Å; F394-L398 PolarHBondContact O-N 3.11Å; I395-L398 WeakPolarHBondContact O-CA 3.38Å; I395-L398 WeakPolarHBondContact O-CB 3.38Å; I395-L398 PolarHBondContact O-N 3.03Å; R396-L398 VanDerWaalsContact C-N 3.32Å; L398-Y401 PolarHBondContact O-N 3.39Å; L398-K402 HydrophobicContact CG-CD 4.36Å; L398-K402 WeakPolarHBondContact O-CB 3.47Å; L398-K402 VanDerWaalsContact O-CG 3.27Å; L398-K402 WeakPolarHBondContact O-CG 3.41Å; L398-K402 PolarHBondContact O-N 2.92Å
399E89.1Confident83.1Confident117 Ų11749 Ų4955%0.54723%0.233SC..Hα-helixtrans-63-47.3175.5-71.2169.8163.900111.7I395 N397 Y401 K402 L403I395-E399 HydrophobicContact CG2-CG 4.31Å; I395-E399 WeakPolarHBondContact CG2-OE1 3.47Å; I395-E399 WeakPolarHBondContact O-CG 3.46Å; I395-E399 PolarHBondContact O-N 3.44Å; N397-E399 PolarHBondContact O-N 2.92Å; E399-Y401 VanDerWaalsContact C-N 3.27Å; E399-Y401 PolarHBondContact O-N 3.41Å; E399-K402 PolarHBondContact O-N 3.37Å; E399-L403 PolarHBondContact O-N 2.77Å
400T85.5Confident81.5Confident13 Ų1348.9 Ų48.98%0.0823%0.234CC..Hα-helixtrans-59.8-41.1176.7-54.20000110.8L237 R396 N397 L403 L404 T698 R699 A702L237-T400 HydrophobicContact CD2-CG2 3.99Å; R396-T400 WeakPolarHBondContact O-CB 3.45Å; R396-T400 PolarHBondContact O-N 2.9Å; R396-T400 PolarHBondContact O-OG1 2.97Å; N397-T400 PolarHBondContact O-N 3.03Å; T400-L403 PolarHBondContact O-N 3.36Å; T400-L404 HydrophobicContact CG2-CD1 3.75Å; T400-L404 HydrophobicContact CG2-CG 4.39Å; T400-L404 WeakPolarHBondContact O-CB 3.37Å; T400-L404 WeakPolarHBondContact O-CG 3.46Å; T400-L404 PolarHBondContact O-N 2.76Å; T400-T698 HydrophobicContact CG2-CG2 4.3Å; T400-R699 HydrophobicContact CG2-CG 4.34Å; T400-A702 HydrophobicContact CG2-CB 4.36Å
401Y90.5Very high79.8Confident6 Ų654.4 Ų54.42%0.02426%0.264CS..Hα-helixtrans-65-45.9178175-95.4000111.8L233 L237 F243 T244 W249 N397 L398 E399 L403 L404 T405L233-Y401 HydrophobicContact CD1-CD1 4.32Å; L233-Y401 HydrophobicContact CD1-CD2 4.41Å; L233-Y401 HydrophobicContact CD1-CG 3.88Å; L237-Y401 HydrophobicContact CD2-CD2 4.31Å; L237-Y401 HydrophobicContact CG-CD2 4.29Å; F243-Y401 VanDerWaalsContact C-OH 3.24Å; F243-Y401 WeakPolarHBondContact CA-OH 3.47Å; T244-Y401 VanDerWaalsContact CB-OH 3.3Å; T244-Y401 WeakPolarHBondContact CB-OH 3.21Å; T244-Y401 PolarHBondContact N-OH 3.45Å; T244-Y401 VanDerWaalsContact OG1-CE2 3.3Å; T244-Y401 WeakPolarHBondContact OG1-CE2 3.25Å; T244-Y401 PolarHBondContact OG1-OH 3.01Å; T244-Y401 VanDerWaalsContact OG1-OH 3.11Å; W249-Y401 HydrophobicContact CZ3-CE1 4.32Å; N397-Y401 VanDerWaalsContact O-CB 3.25Å; N397-Y401 WeakPolarHBondContact O-CB 3.19Å; N397-Y401 PolarHBondContact O-N 2.8Å; L398-Y401 PolarHBondContact O-N 3.39Å; E399-Y401 VanDerWaalsContact C-N 3.27Å; E399-Y401 PolarHBondContact O-N 3.41Å; Y401-L403 PolarHBondContact O-N 2.93Å; Y401-L404 PolarHBondContact O-N 3.34Å; Y401-T405 HydrophobicContact CD2-CG2 3.72Å; Y401-T405 HydrophobicContact CE1-CG2 4.17Å; Y401-T405 HydrophobicContact CE2-CG2 3.31Å; Y401-T405 HydrophobicContact CG-CG2 4.28Å; Y401-T405 WeakPolarHBondContact O-CB 3.26Å; Y401-T405 VanDerWaalsContact O-CG2 3.32Å; Y401-T405 WeakPolarHBondContact O-CG2 3.34Å; Y401-T405 PolarHBondContact O-N 2.71Å; Y401-T405 VanDerWaalsContact O-N 3.08Å; Y401-T405 PolarHBondContact O-OG1 3.42Å
402K87Confident78.3Confident77 Ų7760.1 Ų60.134%0.33529%0.29SS..Hα-helixtrans-58.4-35.4175.9-75.8170.2176.9-179.70112.2W249 L398 E399 K406W249-K402 HydrophobicContact CH2-CG 4.06Å; W249-K402 HydrophobicContact CZ2-CD 4.38Å; W249-K402 VanDerWaalsContact CZ2-CE 3.48Å; W249-K402 HydrophobicContact CZ2-CG 4.31Å; W249-K402 HydrophobicContact CZ3-CG 4.36Å; L398-K402 HydrophobicContact CG-CD 4.36Å; L398-K402 WeakPolarHBondContact O-CB 3.47Å; L398-K402 VanDerWaalsContact O-CG 3.27Å; L398-K402 WeakPolarHBondContact O-CG 3.41Å; L398-K402 PolarHBondContact O-N 2.92Å; E399-K402 PolarHBondContact O-N 3.37Å; K402-K406 WeakPolarHBondContact O-CG 3.34Å
403L80.1Confident76.8Confident30 Ų3061.7 Ų61.716%0.15730%0.296CS..Hα-helixtrans-75.7-49.1179.9-172.855.4000111.9E399 T400 Y401 T405 K406 N446E399-L403 PolarHBondContact O-N 2.77Å; T400-L403 PolarHBondContact O-N 3.36Å; Y401-L403 PolarHBondContact O-N 2.93Å; L403-T405 PolarHBondContact O-N 3.2Å; L403-K406 PolarHBondContact O-N 3.25Å; L403-N446 WeakPolarHBondContact CD2-OD1 3.13Å; L403-N446 VanDerWaalsContact CG-OD1 3.29Å; L403-N446 WeakPolarHBondContact CG-OD1 3.41Å
404L80.8Confident75.6Confident6 Ų666.6 Ų66.63%0.03132%0.321CS..Hα-helixtrans-75.3-20.9-173.5-74.1176.6000115.1L237 T400 Y401 R445 N446 T698L237-L404 HydrophobicContact CD2-CD1 4.25Å; T400-L404 HydrophobicContact CG2-CD1 3.75Å; T400-L404 HydrophobicContact CG2-CG 4.39Å; T400-L404 WeakPolarHBondContact O-CB 3.37Å; T400-L404 WeakPolarHBondContact O-CG 3.46Å; T400-L404 PolarHBondContact O-N 2.76Å; Y401-L404 PolarHBondContact O-N 3.34Å; L404-R445 HydrophobicContact CD2-CB 4.14Å; L404-R445 PolarHBondContact O-NH1 2.81Å; L404-N446 VanDerWaalsContact CD2-ND2 3.31Å; L404-N446 WeakPolarHBondContact CD2-ND2 3.27Å; L404-T698 HydrophobicContact CD1-CG2 3.18Å
405T79.3Confident74.7Confident24 Ų2468.2 Ų68.215%0.14733%0.329CS..THydrogen-bonded Turntrans-90.91.7178.664.30000113.8K262 Y401 L403K262-T405 WeakPolarHBondContact CE-O 3.31Å; K262-T405 VanDerWaalsContact NZ-CB 3.3Å; K262-T405 PolarHBondContact NZ-O 3.41Å; K262-T405 PolarHBondContact NZ-OG1 2.97Å; Y401-T405 HydrophobicContact CD2-CG2 3.72Å; Y401-T405 HydrophobicContact CE1-CG2 4.17Å; Y401-T405 HydrophobicContact CE2-CG2 3.31Å; Y401-T405 HydrophobicContact CG-CG2 4.28Å; Y401-T405 WeakPolarHBondContact O-CB 3.26Å; Y401-T405 VanDerWaalsContact O-CG2 3.32Å; Y401-T405 WeakPolarHBondContact O-CG2 3.34Å; Y401-T405 PolarHBondContact O-N 2.71Å; Y401-T405 VanDerWaalsContact O-N 3.08Å; Y401-T405 PolarHBondContact O-OG1 3.42Å; L403-T405 PolarHBondContact O-N 3.2Å
406K73.7Confident74Confident92 Ų9269.1 Ų69.140%0.433%0.334SS..  trans-63.1145.5167.4-66.5178.5-177.11750109.2K402 L403 W474K402-K406 WeakPolarHBondContact O-CG 3.34Å; L403-K406 PolarHBondContact O-N 3.25Å; K406-W474 WeakPolarHBondContact O-CZ2 3.45Å
407I62.4Low73.6Confident25 Ų2566 Ų6613%0.12832%0.323CS..SBendtrans-82.1-31.5-176.4-59.4164.5000111K262 E265 T266 W474K262-I407 HydrophobicContact CB-CD1 4.02Å; K262-I407 HydrophobicContact CG-CD1 3.42Å; K262-I407 VanDerWaalsContact CG-CD1 3.42Å; K262-I407 HydrophobicContact CG-CG1 3.88Å; E265-I407 HydrophobicContact CB-CD1 3.61Å; E265-I407 HydrophobicContact CB-CG2 4.14Å; E265-I407 HydrophobicContact CG-CD1 4.4Å; E265-I407 VanDerWaalsContact OE2-CD1 3.25Å; E265-I407 WeakPolarHBondContact OE2-CD1 3.48Å; T266-I407 HydrophobicContact CG2-CD1 4.4Å; T266-I407 HydrophobicContact CG2-CG1 4.02Å; T266-I407 HydrophobicContact CG2-CG2 4.48Å; I407-W474 PolarHBondContact O-NE1 2.68Å
408R66Low73.1Confident140 Ų14068.8 Ų68.853%0.52835%0.352SS..SBendtrans-136159.1-180-64.9-177.2179.6171.5-0.1110.2H269H269-R408 PolarHBondContact CE1-NE 2.8Å; H269-R408 PolarHBondContact CE1-NH2 3.4Å; H269-R408 VanDerWaalsContact NE2-CZ 3.33Å; H269-R408 PolarHBondContact NE2-NE 2.82Å; H269-R408 PolarHBondContact NE2-NH2 2.85Å
409P60.1Low72.5Confident50 Ų5071.4 Ų71.433%0.32538%0.38SS..  trans-47.1131.2165.5-29.837.3000111.4M411 L448 W474P409-M411 PolarHBondContact O-N 3.15Å; P409-L448 WeakPolarHBondContact CB-O 3.22Å; P409-L448 WeakPolarHBondContact CG-O 3.23Å; P409-W474 HydrophobicContact CG-CE3 4.2Å; P409-W474 HydrophobicContact CG-CZ3 4.29Å
410P58.8Low72.3Confident39 Ų3969.7 Ų69.725%0.25337%0.372SS..  trans-57.9128.9176.422.1-31.3000110.4D412 S449P410-D412 PolarHBondContact O-N 3.4Å; P410-S449 VanDerWaalsContact CD-O 3.32Å; P410-S449 WeakPolarHBondContact CD-O 3.15Å; P410-S449 WeakPolarHBondContact CG-O 3.14Å
411M54.5Low72.5Confident162 Ų16277.8 Ų77.880%0.79841%0.406SS*.  trans-76.9-18.3-162.8-91.8-161.3-78.100117.4P409P409-M411 PolarHBondContact O-N 3.15Å
412D54.8Low72.7Confident143 Ų14377.7 Ų77.777%0.76541%0.406SS*.SBendtrans-172.1-6.7173.2-104.3-33.8000120.4P410P410-D412 PolarHBondContact O-N 3.4Å
413K52.5Low73.2Confident198 Ų19875.1 Ų75.186%0.86140%0.397SS*.SBendtrans-101.4-17.9-168.3-70-171.8178.5-178.30118.1
414N59Low74.1Confident150 Ų15073.7 Ų73.780%0.80239%0.389SS*.SBendtrans-139.936.6-175.8-74.3-27.3000112.2L416N414-L416 PolarHBondContact O-N 3.25Å
415I72.6Confident75Confident39 Ų3973.4 Ų73.420%0.239%0.388CS..  trans-75.7114.2179.5-62174.2000108.5S417 G418 H450I415-S417 WeakPolarHBondContact CG2-OG 3.31Å; I415-S417 PolarHBondContact O-N 3.28Å; I415-S417 VanDerWaalsContact O-N 3.15Å; I415-G418 PolarHBondContact O-N 3.4Å; I415-H450 HydrophobicContact CG2-CB 4.41Å; I415-H450 VanDerWaalsContact CG2-O 3.31Å; I415-H450 WeakPolarHBondContact CG2-O 3.35Å
416L77.5Confident75.9Confident67 Ų6772.3 Ų72.335%0.35138%0.381SS..THydrogen-bonded Turntrans-57.2-29.2179.1-84.6167.4000112.9N414 G418 E706 V709 R713N414-L416 PolarHBondContact O-N 3.25Å; L416-G418 PolarHBondContact O-N 2.63Å; L416-G418 VanDerWaalsContact O-N 3.17Å; L416-E706 HydrophobicContact CD1-CB 4.31Å; L416-E706 HydrophobicContact CD1-CG 3.9Å; L416-V709 HydrophobicContact CB-CG1 3.8Å; L416-R713 PolarHBondContact O-NH1 3.41Å
417S78.3Confident77.1Confident2 Ų267.9 Ų67.91%0.01436%0.361CS..THydrogen-bonded Turntrans-65.5-13.617780.80000113.5I415 G419 H420 H450I415-S417 WeakPolarHBondContact CG2-OG 3.31Å; I415-S417 PolarHBondContact O-N 3.28Å; I415-S417 VanDerWaalsContact O-N 3.15Å; S417-G419 PolarHBondContact O-N 3.08Å; S417-G419 PolarHBondContact OG-N 3.05Å; S417-H420 VanDerWaalsContact CB-O 3.23Å; S417-H420 WeakPolarHBondContact CB-O 3.31Å; S417-H420 WeakPolarHBondContact O-CB 3.4Å; S417-H420 PolarHBondContact O-CD2 3.35Å; S417-H420 VanDerWaalsContact O-CD2 3.25Å; S417-H420 PolarHBondContact O-N 2.91Å; S417-H420 PolarHBondContact OG-O 3.32Å; S417-H450 WeakPolarHBondContact CB-O 3.14Å; S417-H450 PolarHBondContact OG-O 2.64Å; S417-H450 VanDerWaalsContact OG-O 3.14Å
418G80.5Confident78.8Confident59 Ų5966.7 Ų66.761%0.60836%0.355SS*.THydrogen-bonded Turntrans64.723.7-177.300000113.4I415 L416I415-G418 PolarHBondContact O-N 3.4Å; L416-G418 PolarHBondContact O-N 2.63Å; L416-G418 VanDerWaalsContact O-N 3.17Å
419G80.4Confident80.4Confident61 Ų6160 Ų6063%0.62933%0.33SS*.THydrogen-bonded Turntrans91.8-7.3-177.600000114.5S417S417-G419 PolarHBondContact O-N 3.08Å; S417-G419 PolarHBondContact OG-N 3.05Å
420H84.6Confident82.1Confident81 Ų8157.7 Ų57.738%0.37532%0.315SS..  trans-68.5140.2171.6-66.7-81.7000110.9S417 F422S417-H420 VanDerWaalsContact CB-O 3.23Å; S417-H420 WeakPolarHBondContact CB-O 3.31Å; S417-H420 WeakPolarHBondContact O-CB 3.4Å; S417-H420 PolarHBondContact O-CD2 3.35Å; S417-H420 VanDerWaalsContact O-CD2 3.25Å; S417-H420 PolarHBondContact O-N 2.91Å; S417-H420 PolarHBondContact OG-O 3.32Å; H420-F422 HydrophobicContact CB-CD1 4.48Å; H420-F422 HydrophobicContact CB-CD2 4.44Å; H420-F422 HydrophobicContact CB-CE1 3.79Å; H420-F422 HydrophobicContact CB-CE2 3.76Å; H420-F422 HydrophobicContact CB-CZ 3.37Å; H420-F422 AromaticContact CG-CZ 3.98Å
421K88.4Confident83.9Confident182 Ų18257.4 Ų57.479%0.79132%0.316SS*.  trans-104.688176.9-67.4-174.4179.8-178.90109.8
422F95.7Very high85.9Confident5 Ų551.6 Ų51.62%0.02229%0.291CS..  trans-79.9147.3176.6-55.2-59.7000111.7H420 F424 C452 R453 D512 A712 R713 V716 V722H420-F422 HydrophobicContact CB-CD1 4.48Å; H420-F422 HydrophobicContact CB-CD2 4.44Å; H420-F422 HydrophobicContact CB-CE1 3.79Å; H420-F422 HydrophobicContact CB-CE2 3.76Å; H420-F422 HydrophobicContact CB-CZ 3.37Å; H420-F422 AromaticContact CG-CZ 3.98Å; F422-F424 HydrophobicContact CB-CD1 4.23Å; F422-F424 HydrophobicContact CB-CE1 3.59Å; F422-F424 HydrophobicContact CB-CE2 4.27Å; F422-F424 HydrophobicContact CB-CZ 3.61Å; F422-F424 HydrophobicContact CD2-CZ 4.06Å; F422-F424 HydrophobicContact CG-CE1 4.23Å; F422-F424 HydrophobicContact CG-CZ 4.06Å; F422-C452 CarbonylContact O-C 3.55Å; F422-C452 VanDerWaalsContact O-CA 3.27Å; F422-C452 WeakPolarHBondContact O-CA 3.15Å; F422-C452 WeakPolarHBondContact O-CB 3.37Å; F422-R453 PolarHBondContact O-N 3.39Å; F422-D512 WeakPolarHBondContact CA-OD2 3.42Å; F422-D512 HydrophobicContact CB-CB 4.32Å; F422-D512 HydrophobicContact CD1-CB 4.46Å; F422-A712 HydrophobicContact CD1-CB 3.88Å; F422-A712 HydrophobicContact CD2-CB 3.95Å; F422-A712 HydrophobicContact CE1-CB 3.89Å; F422-A712 HydrophobicContact CE2-CB 3.95Å; F422-A712 HydrophobicContact CG-CB 3.92Å; F422-A712 HydrophobicContact CZ-CB 3.93Å; F422-R713 HydrophobicContact CE2-CB 4.33Å; F422-R713 HydrophobicContact CZ-CB 4.14Å; F422-V716 HydrophobicContact CE1-CG2 3.67Å; F422-V716 HydrophobicContact CZ-CG2 3.88Å; F422-V722 HydrophobicContact CD1-CG2 3.79Å; F422-V722 HydrophobicContact CE1-CG2 3.79Å
423T98.1Very high87.9Confident23 Ų2344.9 Ų44.914%0.14126%0.255CS..EExtended strand (participates in β ladder)trans-106.2110171.3-56.30000109.8R453 Y455 K510 I511 D512T423-R453 CarbonylContact C-O 3.53Å; T423-R453 WeakPolarHBondContact CA-O 3.35Å; T423-Y455 HydrophobicContact CG2-CD2 3.63Å; T423-Y455 HydrophobicContact CG2-CE2 3.64Å; T423-K510 WeakPolarHBondContact CB-O 3.48Å; T423-I511 HydrophobicContact CG2-CD1 3.96Å; T423-D512 PolarHBondContact N-OD2 3.29Å; T423-D512 PolarHBondContact O-N 3.45Å
424F98.5Very high90Very high0 Ų035.4 Ų35.40%021%0.214CC..EExtended strand (participates in β ladder)trans-102.5151.8177.6-60.4-34.3000112.2F422 F443 A447 C452 R453 V454 Y455 D512 G513 L708 V709 A712F422-F424 HydrophobicContact CB-CD1 4.23Å; F422-F424 HydrophobicContact CB-CE1 3.59Å; F422-F424 HydrophobicContact CB-CE2 4.27Å; F422-F424 HydrophobicContact CB-CZ 3.61Å; F422-F424 HydrophobicContact CD2-CZ 4.06Å; F422-F424 HydrophobicContact CG-CE1 4.23Å; F422-F424 HydrophobicContact CG-CZ 4.06Å; F424-F443 HydrophobicContact CB-CE1 4.37Å; F424-F443 HydrophobicContact CB-CZ 3.98Å; F424-F443 HydrophobicContact CD2-CZ 4.19Å; F424-F443 HydrophobicContact CG-CZ 4.41Å; F424-A447 HydrophobicContact CD2-CB 4.21Å; F424-C452 HydrophobicContact CD2-CB 4.09Å; F424-C452 HydrophobicContact CE2-CB 4.08Å; F424-R453 PolarHBondContact N-O 3.09Å; F424-V454 CarbonylContact O-C 3.51Å; F424-V454 WeakPolarHBondContact O-CA 3.41Å; F424-Y455 PolarHBondContact O-N 3.28Å; F424-D512 HydrophobicContact CE1-CB 4.48Å; F424-G513 WeakPolarHBondContact CA-O 3.34Å; F424-L708 HydrophobicContact CE1-CB 4.44Å; F424-L708 HydrophobicContact CE2-CB 4.14Å; F424-L708 HydrophobicContact CZ-CB 4.07Å; F424-V709 HydrophobicContact CE2-CG2 3.7Å; F424-V709 HydrophobicContact CZ-CG2 4.19Å; F424-A712 HydrophobicContact CE1-CB 4Å; F424-A712 HydrophobicContact CZ-CB 4.03Å
425A98.7Very high91.8Very high0 Ų028.3 Ų28.30%018%0.175CC..EExtended strand (participates in β ladder)trans-115.7142.9169.500000111.3Y455 I457 F469 I511 G513 L514 F515A425-Y455 CarbonylContact C-O 3.57Å; A425-Y455 VanDerWaalsContact CA-O 3.24Å; A425-Y455 WeakPolarHBondContact CA-O 3.45Å; A425-I457 HydrophobicContact CB-CD1 3.81Å; A425-I457 HydrophobicContact CB-CG1 4.35Å; A425-F469 HydrophobicContact CB-CE1 4.47Å; A425-I511 HydrophobicContact CB-CD1 3.94Å; A425-I511 HydrophobicContact CB-CG1 4.22Å; A425-I511 HydrophobicContact CB-CG2 3.89Å; A425-G513 PolarHBondContact N-O 3.15Å; A425-L514 HydrophobicContact CB-CD1 3.79Å; A425-F515 PolarHBondContact O-N 2.77Å
426V98.8Very high93Very high0 Ų026.4 Ų26.40%017%0.166CC..EExtended strand (participates in β ladder)trans-123.3138.3173.259.10000111V440 F443 V444 V454 Y455 A456 I457 F515 I517V426-V440 HydrophobicContact CG1-CG1 4.34Å; V426-V440 HydrophobicContact CG2-CG2 4.15Å; V426-F443 HydrophobicContact CB-CD1 3.79Å; V426-F443 HydrophobicContact CB-CE1 3.89Å; V426-F443 HydrophobicContact CG1-CD1 4.17Å; V426-F443 HydrophobicContact CG1-CE1 4.41Å; V426-F443 HydrophobicContact CG2-CD1 4.13Å; V426-V444 HydrophobicContact CG1-CG2 4.37Å; V426-V454 HydrophobicContact CG1-CG1 4.12Å; V426-Y455 PolarHBondContact N-O 3.15Å; V426-A456 HydrophobicContact CG1-CB 4.2Å; V426-A456 WeakPolarHBondContact O-CA 3.33Å; V426-I457 PolarHBondContact O-N 2.8Å; V426-F515 WeakPolarHBondContact CA-O 3.42Å; V426-F515 HydrophobicContact CB-CB 4.34Å; V426-F515 HydrophobicContact CB-CD1 4.33Å; V426-F515 HydrophobicContact CG2-CB 4.33Å; V426-F515 HydrophobicContact CG2-CD1 3.61Å; V426-F515 HydrophobicContact CG2-CE1 4.41Å; V426-F515 HydrophobicContact CG2-CG 4.37Å; V426-I517 HydrophobicContact CG2-CD1 3.81Å
427M98.5Very high93.9Very high0 Ų023.2 Ų23.20%015%0.149CC..EExtended strand (participates in β ladder)trans-150.6153.2173.170.9178.6165.100113.6V429 I457 F461 L464 L514 F515 L516 I517M427-V429 HydrophobicContact CE-CG2 4.29Å; M427-V429 HydrophobicContact CG-CG2 3.97Å; M427-V429 HydrophobicContact SD-CG2 4.25Å; M427-I457 HydrophobicContact CB-CB 3.92Å; M427-I457 HydrophobicContact CB-CD1 4.32Å; M427-I457 HydrophobicContact CG-CD1 4.48Å; M427-I457 HydrophobicContact SD-CB 4.45Å; M427-I457 HydrophobicContact SD-CD1 3.99Å; M427-I457 HydrophobicContact SD-CG2 4.38Å; M427-F461 HydrophobicContact CE-CD1 4.02Å; M427-F461 HydrophobicContact CE-CD2 4.24Å; M427-F461 HydrophobicContact CE-CE1 3.41Å; M427-F461 VanDerWaalsContact CE-CE1 3.41Å; M427-F461 HydrophobicContact CE-CE2 3.67Å; M427-F461 HydrophobicContact CE-CG 4.41Å; M427-F461 HydrophobicContact CE-CZ 3.21Å; M427-L464 HydrophobicContact CE-CD1 4.06Å; M427-L464 HydrophobicContact SD-CD1 4.17Å; M427-L514 HydrophobicContact CE-CD1 4.43Å; M427-L514 HydrophobicContact CE-CD2 4.27Å; M427-F515 PolarHBondContact N-O 2.88Å; M427-L516 HydrophobicContact CE-CD2 3.14Å; M427-L516 HydrophobicContact CG-CD2 3.81Å; M427-L516 HydrophobicContact SD-CD2 4.3Å; M427-I517 PolarHBondContact O-N 3.4Å
428N98.7Very high94.8Very high0 Ų023.2 Ų23.20%015%0.149CC..EExtended strand (participates in β ladder)trans-94.4138.2173.1-63.2-21.3000109.4M436 S460 S486 I517N428-M436 HydrophobicContact CB-SD 4.08Å; N428-S460 WeakPolarHBondContact O-CB 3.43Å; N428-S460 PolarHBondContact O-OG 2.97Å; N428-S486 PolarHBondContact ND2-OG 3.46Å; N428-I517 CarbonylContact C-O 3.37Å; N428-I517 WeakPolarHBondContact CA-O 3.41Å; N428-I517 WeakPolarHBondContact OD1-CB 3.32Å; N428-I517 WeakPolarHBondContact OD1-CD1 3.1Å
429V98.4Very high95.6Very high0 Ų020.4 Ų20.40%012%0.12CC..EExtended strand (participates in β ladder)trans-138127.1-178.6-173.90000110.8M427 F461 L516 I517 G518 G519 E521 A522M427-V429 HydrophobicContact CE-CG2 4.29Å; M427-V429 HydrophobicContact CG-CG2 3.97Å; M427-V429 HydrophobicContact SD-CG2 4.25Å; V429-F461 HydrophobicContact CG1-CD2 4.33Å; V429-F461 HydrophobicContact CG1-CE2 4.12Å; V429-F461 HydrophobicContact CG2-CD2 4.35Å; V429-F461 HydrophobicContact CG2-CE2 3.93Å; V429-L516 HydrophobicContact CG2-CD2 4.1Å; V429-I517 PolarHBondContact N-O 2.84Å; V429-G518 VanDerWaalsContact O-CA 3.23Å; V429-G518 WeakPolarHBondContact O-CA 3.27Å; V429-G519 PolarHBondContact O-N 2.99Å; V429-G519 VanDerWaalsContact O-N 3.09Å; V429-E521 HydrophobicContact CG1-CB 3.96Å; V429-A522 HydrophobicContact CB-CB 3.96Å
430G97.1Very high96.4Very high1 Ų117.5 Ų17.51%0.019%0.09CC..SBendtrans110.5-156-179.500000113.1T490 Q491G430-T490 PolarHBondContact N-OG1 2.8Å; G430-T490 WeakPolarHBondContact O-CG2 3.4Å; G430-T490 PolarHBondContact O-OG1 3.46Å; G430-Q491 PolarHBondContact N-O 2.86Å
431A96.1Very high97Very high33 Ų3314 Ų1427%0.2737%0.074SC..SBendtrans-75.6146.8176.600000111.2M436A431-M436 WeakPolarHBondContact O-CE 3.06Å
432P96.4Very high97.3Very high40 Ų405.3 Ų5.326%0.264%0.036SC..  trans-63.5141.4176.826.6-33.3000111.2T490P432-T490 HydrophobicContact CB-CG2 3.89Å; P432-T490 HydrophobicContact CG-CG2 4.41Å
433A96.6Very high97.3Very high1 Ų15.1 Ų5.11%0.0084%0.035CC..  trans-144.5147176.100000110.1G435 M436 I550A433-G435 PolarHBondContact O-N 3.27Å; A433-M436 HydrophobicContact CB-CE 4.45Å; A433-M436 WeakPolarHBondContact O-CG 3.4Å; A433-M436 PolarHBondContact O-N 3.26Å; A433-I550 HydrophobicContact CB-CG2 4.27Å
434C96.6Very high97.2Very high0 Ų04 Ų40%03%0.028CC..THydrogen-bonded Turntrans-53134.3171.3-83.40000111.2I561 G562 S565 Q685 P689C434-I561 WeakPolarHBondContact O-CG2 3.4Å; C434-G562 WeakPolarHBondContact O-CA 3.15Å; C434-G562 PolarHBondContact O-N 3.06Å; C434-S565 VanDerWaalsContact CB-CB 3.48Å; C434-S565 VanDerWaalsContact CB-OG 3.25Å; C434-S565 WeakPolarHBondContact CB-OG 3.32Å; C434-Q685 PolarHBondContact SG-O 3.14Å; C434-P689 HydrophobicContact CB-CB 3.7Å
435G96.4Very high96.9Very high0 Ų05.3 Ų5.30%03%0.033CC..THydrogen-bonded Turntrans100.5-13.6179.600000115.4A433 N437 A438 A439 A697A433-G435 PolarHBondContact O-N 3.27Å; G435-N437 PolarHBondContact O-N 3.27Å; G435-A438 PolarHBondContact O-N 3.31Å; G435-A439 WeakPolarHBondContact O-CB 3.1Å; G435-A439 PolarHBondContact O-N 2.6Å; G435-A697 WeakPolarHBondContact O-CB 3.49Å
436M97.9Very high96.5Very high0 Ų05.4 Ų5.40%03%0.033CC..Hα-helixtrans-55.4-49173.7-74.2-175.9169.100112.2N428 A431 A433 A438 A439 V440 T490 I517 C548N428-M436 HydrophobicContact CB-SD 4.08Å; A431-M436 WeakPolarHBondContact O-CE 3.06Å; A433-M436 HydrophobicContact CB-CE 4.45Å; A433-M436 WeakPolarHBondContact O-CG 3.4Å; A433-M436 PolarHBondContact O-N 3.26Å; M436-A438 PolarHBondContact O-N 2.53Å; M436-A439 PolarHBondContact O-N 2.8Å; M436-V440 WeakPolarHBondContact O-CG2 3.3Å; M436-V440 PolarHBondContact O-N 3.41Å; M436-T490 HydrophobicContact SD-CG2 4.36Å; M436-I517 HydrophobicContact CG-CG2 4.23Å; M436-C548 HydrophobicContact CG-CB 4.42Å; M436-C548 WeakPolarHBondContact CG-SG 3.28Å
437N97.7Very high96.2Very high0 Ų05.4 Ų5.40%03%0.033CC..Hα-helixtrans-64.2-39.3179.5-61.2-36.6000112.2G435 V440 R441 W480 F483 G484 G485 S486 F487G435-N437 PolarHBondContact O-N 3.27Å; N437-V440 PolarHBondContact O-N 3.08Å; N437-R441 WeakPolarHBondContact O-CB 3.41Å; N437-R441 PolarHBondContact O-N 3.32Å; N437-W480 HydrophobicContact CB-CB 4.13Å; N437-W480 HydrophobicContact CB-CE3 4.3Å; N437-W480 WeakPolarHBondContact CB-O 3Å; N437-F483 PolarHBondContact ND2-O 2.57Å; N437-G484 PolarHBondContact ND2-O 3.25Å; N437-G485 PolarHBondContact ND2-O 3.29Å; N437-S486 WeakPolarHBondContact OD1-CA 3.21Å; N437-F487 PolarHBondContact OD1-N 3.14Å
438A96.5Very high95.9Very high1 Ų16.6 Ų6.61%0.0084%0.04CC..Hα-helixtrans-64.1-40.2175.600000112.1G435 M436 S442 A697G435-A438 PolarHBondContact O-N 3.31Å; M436-A438 PolarHBondContact O-N 2.53Å; A438-S442 WeakPolarHBondContact O-CB 3.42Å; A438-S442 PolarHBondContact O-N 2.64Å; A438-A697 HydrophobicContact CB-CB 3.87Å
439A97.8Very high95.3Very high0 Ų06.7 Ų6.70%04%0.04CC..Hα-helixtrans-64.9-49.1175.500000111.6G435 M436 R441 S442 F443 I517 L546 A697 A701G435-A439 WeakPolarHBondContact O-CB 3.1Å; G435-A439 PolarHBondContact O-N 2.6Å; M436-A439 PolarHBondContact O-N 2.8Å; A439-R441 VanDerWaalsContact C-N 3.32Å; A439-R441 PolarHBondContact O-N 2.92Å; A439-S442 PolarHBondContact O-N 3.09Å; A439-F443 WeakPolarHBondContact O-CB 3.27Å; A439-F443 PolarHBondContact O-N 3.1Å; A439-I517 HydrophobicContact CB-CD1 3.78Å; A439-I517 HydrophobicContact CB-CG1 4.31Å; A439-I517 HydrophobicContact CB-CG2 4.23Å; A439-L546 HydrophobicContact CB-CD2 3.72Å; A439-A697 HydrophobicContact CB-CB 4.12Å; A439-A701 HydrophobicContact CB-CB 4.03Å; A439-A701 WeakPolarHBondContact O-CB 3.2Å
440V98.2Very high94.8Very high0 Ų07.1 Ų7.10%04%0.042CC..Hα-helixtrans-56.3-48.7176.4174.10000110.3V426 M436 N437 S442 F443 V444 V477 W480 L488 I517V426-V440 HydrophobicContact CG1-CG1 4.34Å; V426-V440 HydrophobicContact CG2-CG2 4.15Å; M436-V440 WeakPolarHBondContact O-CG2 3.3Å; M436-V440 PolarHBondContact O-N 3.41Å; N437-V440 PolarHBondContact O-N 3.08Å; V440-S442 PolarHBondContact O-N 3.31Å; V440-F443 PolarHBondContact O-N 3.39Å; V440-V444 HydrophobicContact CG1-CG2 4.15Å; V440-V444 WeakPolarHBondContact O-CB 3.4Å; V440-V444 VanDerWaalsContact O-CG2 3.29Å; V440-V444 WeakPolarHBondContact O-CG2 3.18Å; V440-V444 PolarHBondContact O-N 3.37Å; V440-V477 HydrophobicContact CG1-CG1 4.38Å; V440-W480 HydrophobicContact CB-CE3 4.29Å; V440-W480 HydrophobicContact CB-CZ3 4.19Å; V440-W480 HydrophobicContact CG1-CE3 4.13Å; V440-W480 HydrophobicContact CG1-CZ3 3.7Å; V440-L488 HydrophobicContact CG1-CD1 4.06Å; V440-L488 HydrophobicContact CG2-CD1 3.81Å; V440-L488 HydrophobicContact CG2-CG 4.42Å; V440-I517 HydrophobicContact CB-CD1 4.44Å; V440-I517 HydrophobicContact CG2-CD1 3.53Å
441R95.5Very high94.3Very high8 Ų88.9 Ų8.93%0.036%0.061CC..Hα-helixtrans-55.2-53.3178.1173.2-170.9172.8-91.68.2112.3E240 N437 A439 F443 V444 R445 V477 W480E240-R441 VanDerWaalsContact CD-CD 3.44Å; E240-R441 VanDerWaalsContact CG-CZ 3.48Å; E240-R441 VanDerWaalsContact CG-NH2 3.34Å; E240-R441 WeakPolarHBondContact OE1-CD 3.41Å; E240-R441 IonicContact OE1-CZ 3.38Å; E240-R441 IonicContact OE1-NE 3.68Å; E240-R441 PolarHBondContact OE1-NE 3.24Å; E240-R441 VanDerWaalsContact OE1-NE 3.09Å; E240-R441 IonicContact OE2-CZ 2.66Å; E240-R441 IonicContact OE2-NE 2.9Å; E240-R441 PolarHBondContact OE2-NE 3.11Å; E240-R441 IonicContact OE2-NH2 3.59Å; E240-R441 PolarHBondContact OE2-NH2 3.33Å; N437-R441 WeakPolarHBondContact O-CB 3.41Å; N437-R441 PolarHBondContact O-N 3.32Å; A439-R441 VanDerWaalsContact C-N 3.32Å; A439-R441 PolarHBondContact O-N 2.92Å; R441-F443 VanDerWaalsContact C-N 3.32Å; R441-F443 PolarHBondContact O-N 2.98Å; R441-V444 PolarHBondContact O-N 3.06Å; R441-R445 PolarHBondContact O-N 3.12Å; R441-V477 HydrophobicContact CB-CB 3.89Å; R441-V477 HydrophobicContact CB-CG2 4.2Å; R441-V477 WeakPolarHBondContact CD-O 3.24Å; R441-V477 HydrophobicContact CG-CB 3.98Å; R441-V477 HydrophobicContact CG-CG2 3.85Å; R441-V477 WeakPolarHBondContact CG-O 3.43Å; R441-W480 HydrophobicContact CB-CB 4.18Å
442S94.7Very high94.2Very high0 Ų07.6 Ų7.60%05%0.049CC..Hα-helixtrans-62.8-43.4-176.7-177.10000110.6A438 A439 V440 N446 T698 A702A438-S442 WeakPolarHBondContact O-CB 3.42Å; A438-S442 PolarHBondContact O-N 2.64Å; A439-S442 PolarHBondContact O-N 3.09Å; V440-S442 PolarHBondContact O-N 3.31Å; S442-N446 WeakPolarHBondContact O-CB 3.49Å; S442-N446 PolarHBondContact O-N 2.92Å; S442-N446 PolarHBondContact O-ND2 3.11Å; S442-N446 PolarHBondContact OG-ND2 3.47Å; S442-T698 WeakPolarHBondContact CB-O 3.49Å; S442-T698 PolarHBondContact OG-O 3.21Å; S442-A702 PolarHBondContact OG-N 3.28Å
443F96.8Very high94.2Very high0 Ų011.1 Ų11.10%06%0.057CC..Hα-helixtrans-59.5-51.9176.3177.6-101.7000112.3F424 V426 A439 V440 R441 R445 N446 A447 V454 F515 A701 A705 L708F424-F443 HydrophobicContact CB-CE1 4.37Å; F424-F443 HydrophobicContact CB-CZ 3.98Å; F424-F443 HydrophobicContact CD2-CZ 4.19Å; F424-F443 HydrophobicContact CG-CZ 4.41Å; V426-F443 HydrophobicContact CB-CD1 3.79Å; V426-F443 HydrophobicContact CB-CE1 3.89Å; V426-F443 HydrophobicContact CG1-CD1 4.17Å; V426-F443 HydrophobicContact CG1-CE1 4.41Å; V426-F443 HydrophobicContact CG2-CD1 4.13Å; A439-F443 WeakPolarHBondContact O-CB 3.27Å; A439-F443 PolarHBondContact O-N 3.1Å; V440-F443 PolarHBondContact O-N 3.39Å; R441-F443 VanDerWaalsContact C-N 3.32Å; R441-F443 PolarHBondContact O-N 2.98Å; F443-R445 PolarHBondContact O-N 3.41Å; F443-N446 PolarHBondContact O-N 2.9Å; F443-A447 HydrophobicContact CZ-CB 4.39Å; F443-A447 WeakPolarHBondContact O-CB 3.38Å; F443-A447 PolarHBondContact O-N 2.79Å; F443-V454 HydrophobicContact CD1-CG1 4.3Å; F443-V454 HydrophobicContact CE1-CG1 3.92Å; F443-F515 HydrophobicContact CB-CD1 3.73Å; F443-F515 HydrophobicContact CB-CE1 3.64Å; F443-F515 HydrophobicContact CD1-CB 4.44Å; F443-F515 AromaticContact CD1-CD1 3.77Å; F443-F515 HydrophobicContact CD1-CD1 3.77Å; F443-F515 HydrophobicContact CD1-CG 4.5Å; F443-F515 HydrophobicContact CD2-CB 4.29Å; F443-F515 AromaticContact CD2-CD1 3.48Å; F443-F515 HydrophobicContact CD2-CD1 3.48Å; F443-F515 VanDerWaalsContact CD2-CD1 3.48Å; F443-F515 AromaticContact CD2-CE1 3.91Å; F443-F515 HydrophobicContact CD2-CE1 3.91Å; F443-F515 AromaticContact CD2-CG 3.92Å; F443-F515 HydrophobicContact CD2-CG 3.92Å; F443-F515 HydrophobicContact CE1-CB 4.08Å; F443-F515 HydrophobicContact CE1-CD1 4.25Å; F443-F515 HydrophobicContact CE2-CB 3.94Å; F443-F515 HydrophobicContact CE2-CD1 4.03Å; F443-F515 HydrophobicContact CE2-CG 4.04Å; F443-F515 AromaticContact CG-CD1 3.34Å; F443-F515 HydrophobicContact CG-CD1 3.34Å; F443-F515 AromaticContact CG-CE1 3.77Å; F443-F515 HydrophobicContact CG-CE1 3.77Å; F443-F515 HydrophobicContact CG-CG 4.17Å; F443-F515 HydrophobicContact CZ-CB 3.82Å; F443-F515 HydrophobicContact CZ-CD1 4.37Å; F443-F515 HydrophobicContact CZ-CG 4.35Å; F443-A701 HydrophobicContact CB-CB 4.25Å; F443-A705 HydrophobicContact CD2-CB 3.74Å; F443-A705 HydrophobicContact CE2-CB 3.96Å; F443-L708 HydrophobicContact CE2-CD1 3.69Å; F443-L708 HydrophobicContact CZ-CD1 3.82Å
444V95.6Very high94.2Very high0 Ų011 Ų110%06%0.057CC..Hα-helixtrans-55.6-51.9-179.8168.70000110.4V426 V440 R441 N446 A447 L448 V454 M472 V477V426-V444 HydrophobicContact CG1-CG2 4.37Å; V440-V444 HydrophobicContact CG1-CG2 4.15Å; V440-V444 WeakPolarHBondContact O-CB 3.4Å; V440-V444 VanDerWaalsContact O-CG2 3.29Å; V440-V444 WeakPolarHBondContact O-CG2 3.18Å; V440-V444 PolarHBondContact O-N 3.37Å; R441-V444 PolarHBondContact O-N 3.06Å; V444-N446 PolarHBondContact O-N 3.07Å; V444-A447 PolarHBondContact O-N 3.45Å; V444-L448 HydrophobicContact CG1-CD1 3.72Å; V444-L448 HydrophobicContact CG1-CG 4.35Å; V444-L448 WeakPolarHBondContact O-CB 3.27Å; V444-L448 WeakPolarHBondContact O-CG 3.3Å; V444-L448 PolarHBondContact O-N 2.73Å; V444-V454 HydrophobicContact CG2-CG1 3.95Å; V444-M472 HydrophobicContact CG1-CB 3.97Å; V444-M472 HydrophobicContact CG2-CB 4.28Å; V444-M472 HydrophobicContact CG2-CE 4.35Å; V444-M472 HydrophobicContact CG2-CG 4.36Å; V444-V477 HydrophobicContact CB-CG1 4.14Å; V444-V477 HydrophobicContact CB-CG2 4.22Å; V444-V477 HydrophobicContact CG1-CG1 4.21Å; V444-V477 HydrophobicContact CG1-CG2 4.06Å; V444-V477 HydrophobicContact CG2-CG1 4.07Å
445R91.9Very high94.3Very high28 Ų2812.3 Ų12.311%0.1066%0.062CC..Hα-helixtrans-62.6-43.4-179.6-77.4-171.1157.1-169-0.2112.8L404 R441 F443 S449 W474 V477L404-R445 HydrophobicContact CD2-CB 4.14Å; L404-R445 PolarHBondContact O-NH1 2.81Å; R441-R445 PolarHBondContact O-N 3.12Å; F443-R445 PolarHBondContact O-N 3.41Å; R445-S449 WeakPolarHBondContact O-CB 3.15Å; R445-S449 PolarHBondContact O-N 2.97Å; R445-W474 HydrophobicContact CB-CE3 4.35Å; R445-W474 HydrophobicContact CB-CH2 3.96Å; R445-W474 HydrophobicContact CB-CZ2 4.32Å; R445-W474 HydrophobicContact CB-CZ3 3.99Å; R445-W474 HydrophobicContact CG-CD2 4.07Å; R445-W474 HydrophobicContact CG-CE3 4.15Å; R445-W474 HydrophobicContact CG-CH2 4.15Å; R445-W474 HydrophobicContact CG-CZ2 4.05Å; R445-W474 HydrophobicContact CG-CZ3 4.22Å; R445-W474 WeakPolarHBondContact O-CZ3 3.09Å; R445-V477 HydrophobicContact CG-CG2 4.17Å
446N91.2Very high94.4Very high1 Ų112.3 Ų12.31%0.0056%0.062CC..Hα-helixtrans-67.6-44-179.8-77.3-72.1000112L403 L404 S442 F443 V444 S449 H450 A702 A705L403-N446 WeakPolarHBondContact CD2-OD1 3.13Å; L403-N446 VanDerWaalsContact CG-OD1 3.29Å; L403-N446 WeakPolarHBondContact CG-OD1 3.41Å; L404-N446 VanDerWaalsContact CD2-ND2 3.31Å; L404-N446 WeakPolarHBondContact CD2-ND2 3.27Å; S442-N446 WeakPolarHBondContact O-CB 3.49Å; S442-N446 PolarHBondContact O-N 2.92Å; S442-N446 PolarHBondContact O-ND2 3.11Å; S442-N446 PolarHBondContact OG-ND2 3.47Å; F443-N446 PolarHBondContact O-N 2.9Å; V444-N446 PolarHBondContact O-N 3.07Å; N446-S449 WeakPolarHBondContact O-CB 3.29Å; N446-S449 PolarHBondContact O-N 3.21Å; N446-S449 VanDerWaalsContact O-N 3.17Å; N446-S449 PolarHBondContact O-OG 3.36Å; N446-H450 PolarHBondContact O-CD2 2.91Å; N446-H450 PolarHBondContact O-N 3.38Å; N446-A702 WeakPolarHBondContact ND2-CB 3.44Å; N446-A705 HydrophobicContact CB-CB 3.61Å
447A92.9Very high94.5Very high0 Ų012.3 Ų12.30%06%0.062CC..Hα-helixtrans-63.4-45.1177.500000112.1F424 F443 V444 S449 H450 C452 V454F424-A447 HydrophobicContact CD2-CB 4.21Å; F443-A447 HydrophobicContact CZ-CB 4.39Å; F443-A447 WeakPolarHBondContact O-CB 3.38Å; F443-A447 PolarHBondContact O-N 2.79Å; V444-A447 PolarHBondContact O-N 3.45Å; A447-S449 VanDerWaalsContact C-N 3.25Å; A447-S449 PolarHBondContact O-N 3.33Å; A447-H450 CarbonylContact O-C 3.6Å; A447-H450 WeakPolarHBondContact O-CA 3.38Å; A447-H450 PolarHBondContact O-N 3.29Å; A447-C452 HydrophobicContact CB-CB 4.4Å; A447-C452 WeakPolarHBondContact O-CB 3.38Å; A447-C452 PolarHBondContact O-N 3.06Å; A447-V454 HydrophobicContact CB-CG2 3.51Å
448L91.4Very high94.5Very high25 Ų2516.9 Ų16.913%0.1318%0.082CC..Hα-helixtrans-60.2-36.9173.5-68.5174.2000111.6P409 V444 H450 G451 C452 V454 W474P409-L448 WeakPolarHBondContact CB-O 3.22Å; P409-L448 WeakPolarHBondContact CG-O 3.23Å; V444-L448 HydrophobicContact CG1-CD1 3.72Å; V444-L448 HydrophobicContact CG1-CG 4.35Å; V444-L448 WeakPolarHBondContact O-CB 3.27Å; V444-L448 WeakPolarHBondContact O-CG 3.3Å; V444-L448 PolarHBondContact O-N 2.73Å; L448-H450 PolarHBondContact O-N 3.38Å; L448-G451 PolarHBondContact O-N 2.92Å; L448-C452 WeakPolarHBondContact CD2-O 3.36Å; L448-V454 HydrophobicContact CD2-CG2 4.36Å; L448-V454 HydrophobicContact CG-CG2 4.36Å; L448-W474 HydrophobicContact CB-CE3 4.19Å; L448-W474 HydrophobicContact CD1-CB 4.32Å; L448-W474 HydrophobicContact CD1-CE3 4.4Å
449S86.1Confident94.5Very high2 Ų220.1 Ų20.11%0.01410%0.099CC..Hα-helixtrans-63-19.8175.688.70000113.6P410 R445 N446 A447P410-S449 VanDerWaalsContact CD-O 3.32Å; P410-S449 WeakPolarHBondContact CD-O 3.15Å; P410-S449 WeakPolarHBondContact CG-O 3.14Å; R445-S449 WeakPolarHBondContact O-CB 3.15Å; R445-S449 PolarHBondContact O-N 2.97Å; N446-S449 WeakPolarHBondContact O-CB 3.29Å; N446-S449 PolarHBondContact O-N 3.21Å; N446-S449 VanDerWaalsContact O-N 3.17Å; N446-S449 PolarHBondContact O-OG 3.36Å; A447-S449 VanDerWaalsContact C-N 3.25Å; A447-S449 PolarHBondContact O-N 3.33Å
450H87.3Confident94.5Very high10 Ų1020.1 Ų20.15%0.04610%0.099CC..THydrogen-bonded Turntrans-9917173.9-62.7-45.4000113.3I415 S417 N446 A447 L448 C452 V709I415-H450 HydrophobicContact CG2-CB 4.41Å; I415-H450 VanDerWaalsContact CG2-O 3.31Å; I415-H450 WeakPolarHBondContact CG2-O 3.35Å; S417-H450 WeakPolarHBondContact CB-O 3.14Å; S417-H450 PolarHBondContact OG-O 2.64Å; S417-H450 VanDerWaalsContact OG-O 3.14Å; N446-H450 PolarHBondContact O-CD2 2.91Å; N446-H450 PolarHBondContact O-N 3.38Å; A447-H450 CarbonylContact O-C 3.6Å; A447-H450 WeakPolarHBondContact O-CA 3.38Å; A447-H450 PolarHBondContact O-N 3.29Å; L448-H450 PolarHBondContact O-N 3.38Å; H450-C452 PolarHBondContact O-N 3.24Å; H450-V709 HydrophobicContact CB-CG1 4.47Å; H450-V709 HydrophobicContact CB-CG2 4.04Å
451G87.2Confident94.5Very high38 Ų3820.1 Ų20.139%0.39210%0.099SC..THydrogen-bonded Turntrans70.513.2177.700000114.4L448L448-G451 PolarHBondContact O-N 2.92Å
452C93Very high94.6Very high5 Ų521.3 Ų21.33%0.03411%0.106CC..  trans-82153.2176-55.80000110.1F422 F424 A447 L448 H450F422-C452 CarbonylContact O-C 3.55Å; F422-C452 VanDerWaalsContact O-CA 3.27Å; F422-C452 WeakPolarHBondContact O-CA 3.15Å; F422-C452 WeakPolarHBondContact O-CB 3.37Å; F424-C452 HydrophobicContact CD2-CB 4.09Å; F424-C452 HydrophobicContact CE2-CB 4.08Å; A447-C452 HydrophobicContact CB-CB 4.4Å; A447-C452 WeakPolarHBondContact O-CB 3.38Å; A447-C452 PolarHBondContact O-N 3.06Å; L448-C452 WeakPolarHBondContact CD2-O 3.36Å; H450-C452 PolarHBondContact O-N 3.24Å
453R96.1Very high94.8Very high114 Ų11421.3 Ų21.343%0.4311%0.106SC..EExtended strand (participates in β ladder)trans-91.1142.8166.9-169.9178.9-170.81785109.1F422 T423 F424 Y455 D471F422-R453 PolarHBondContact O-N 3.39Å; T423-R453 CarbonylContact C-O 3.53Å; T423-R453 WeakPolarHBondContact CA-O 3.35Å; F424-R453 PolarHBondContact N-O 3.09Å; R453-Y455 PolarHBondContact NH1-OH 2.82Å; R453-Y455 PolarHBondContact NH2-OH 2.91Å; R453-D471 IonicContact CZ-OD1 2.62Å; R453-D471 IonicContact CZ-OD2 2.73Å; R453-D471 VanDerWaalsContact CZ-OD2 3.29Å; R453-D471 IonicContact NE-OD1 3.99Å; R453-D471 PolarHBondContact NE-OD1 3.22Å; R453-D471 VanDerWaalsContact NE-OD1 3.09Å; R453-D471 IonicContact NE-OD2 3.42Å; R453-D471 PolarHBondContact NE-OD2 3.29Å; R453-D471 VanDerWaalsContact NE-OD2 3.1Å; R453-D471 IonicContact NH2-OD1 3.98Å; R453-D471 IonicContact NH2-OD2 2.8Å; R453-D471 PolarHBondContact NH2-OD2 2.65Å
454V98.2Very high94.8Very high0 Ų021.4 Ų21.40%011%0.107CC..EExtended strand (participates in β ladder)trans-127125.7-178.5-1740000110.6F424 V426 F443 V444 A447 L448 M472F424-V454 CarbonylContact O-C 3.51Å; F424-V454 WeakPolarHBondContact O-CA 3.41Å; V426-V454 HydrophobicContact CG1-CG1 4.12Å; F443-V454 HydrophobicContact CD1-CG1 4.3Å; F443-V454 HydrophobicContact CE1-CG1 3.92Å; V444-V454 HydrophobicContact CG2-CG1 3.95Å; A447-V454 HydrophobicContact CB-CG2 3.51Å; L448-V454 HydrophobicContact CD2-CG2 4.36Å; L448-V454 HydrophobicContact CG-CG2 4.36Å; V454-M472 HydrophobicContact CB-CB 4.37Å; V454-M472 WeakPolarHBondContact O-CB 3.37Å; V454-M472 PolarHBondContact O-N 3.17Å
455Y98.7Very high94.9Very high27 Ų2722.7 Ų22.711%0.10611%0.113CC..EExtended strand (participates in β ladder)trans-101.4136.9166.8-74-75.2000111.2T423 F424 A425 V426 R453 F469 K470 D471 F509 I511T423-Y455 HydrophobicContact CG2-CD2 3.63Å; T423-Y455 HydrophobicContact CG2-CE2 3.64Å; F424-Y455 PolarHBondContact O-N 3.28Å; A425-Y455 CarbonylContact C-O 3.57Å; A425-Y455 VanDerWaalsContact CA-O 3.24Å; A425-Y455 WeakPolarHBondContact CA-O 3.45Å; V426-Y455 PolarHBondContact N-O 3.15Å; R453-Y455 PolarHBondContact NH1-OH 2.82Å; R453-Y455 PolarHBondContact NH2-OH 2.91Å; Y455-F469 HydrophobicContact CD1-CB 4.04Å; Y455-F469 HydrophobicContact CD1-CD1 4.33Å; Y455-F469 HydrophobicContact CG-CD1 4.01Å; Y455-K470 CarbonylContact C-O 3.58Å; Y455-K470 WeakPolarHBondContact CA-O 3.48Å; Y455-D471 HydrophobicContact CD1-CB 4.12Å; Y455-D471 HydrophobicContact CE1-CB 3.75Å; Y455-F509 HydrophobicContact CD1-CD1 4.49Å; Y455-F509 HydrophobicContact CE1-CD1 4.1Å; Y455-F509 HydrophobicContact CE1-CE1 4.33Å; Y455-F509 HydrophobicContact CE2-CD1 4.18Å; Y455-F509 AromaticContact CZ-CD1 3.93Å; Y455-I511 HydrophobicContact CD2-CD1 3.98Å
456A98.6Very high95.2Very high0 Ų029 Ų290%014%0.142CC..EExtended strand (participates in β ladder)trans-97.2128.6164.600000110.2V426 F469 K470 M472 L488V426-A456 HydrophobicContact CG1-CB 4.2Å; V426-A456 WeakPolarHBondContact O-CA 3.33Å; A456-F469 CarbonylContact O-C 3.48Å; A456-F469 WeakPolarHBondContact O-CA 3.47Å; A456-K470 PolarHBondContact N-O 2.89Å; A456-K470 PolarHBondContact O-N 3.4Å; A456-M472 HydrophobicContact CB-CE 4.32Å; A456-M472 HydrophobicContact CB-CG 3.61Å; A456-M472 HydrophobicContact CB-SD 3.44Å; A456-M472 WeakPolarHBondContact CB-SD 3.18Å; A456-L488 HydrophobicContact CB-CD1 3.97Å; A456-L488 HydrophobicContact CB-CD2 3.61Å; A456-L488 HydrophobicContact CB-CG 4.46Å
457I98.6Very high95.4Very high0 Ų030 Ų300%015%0.152CC..EExtended strand (participates in β ladder)trans-94.4123.7175-56.8157.4000108A425 V426 M427 S460 L464 F469 L514A425-I457 HydrophobicContact CB-CD1 3.81Å; A425-I457 HydrophobicContact CB-CG1 4.35Å; V426-I457 PolarHBondContact O-N 2.8Å; M427-I457 HydrophobicContact CB-CB 3.92Å; M427-I457 HydrophobicContact CB-CD1 4.32Å; M427-I457 HydrophobicContact CG-CD1 4.48Å; M427-I457 HydrophobicContact SD-CB 4.45Å; M427-I457 HydrophobicContact SD-CD1 3.99Å; M427-I457 HydrophobicContact SD-CG2 4.38Å; I457-S460 WeakPolarHBondContact CG2-O 3.41Å; I457-L464 HydrophobicContact CD1-CD1 3.89Å; I457-L464 HydrophobicContact CD1-CG 4.22Å; I457-L464 HydrophobicContact CG2-CB 3.74Å; I457-L464 HydrophobicContact CG2-CG 4.24Å; I457-F469 HydrophobicContact CD1-CE1 3.87Å; I457-F469 HydrophobicContact CD1-CZ 3.92Å; I457-F469 HydrophobicContact CG1-CD1 3.83Å; I457-F469 HydrophobicContact CG1-CE1 3.49Å; I457-F469 VanDerWaalsContact CG1-CE1 3.49Å; I457-F469 HydrophobicContact CG1-CE2 4.22Å; I457-F469 HydrophobicContact CG1-CG 4.32Å; I457-F469 HydrophobicContact CG1-CZ 3.7Å; I457-L514 HydrophobicContact CD1-CD1 4.28Å
458K98Very high95.7Very high96 Ų9632.4 Ų32.442%0.41717%0.168SC..THydrogen-bonded Turntrans-79.4149176.3-65-172.4176.7-176.30111.2S460 G463 C468 L488K458-S460 VanDerWaalsContact C-N 3.26Å; K458-S460 PolarHBondContact O-N 3.14Å; K458-G463 WeakPolarHBondContact O-CA 3.39Å; K458-C468 HydrophobicContact CB-CB 4.22Å; K458-C468 PolarHBondContact N-O 3.17Å; K458-L488 CarbonylContact C-O 3.53Å; K458-L488 WeakPolarHBondContact CA-O 3.34Å
459D97.6Very high96Very high69 Ų6932.7 Ų32.737%0.36917%0.168SC..THydrogen-bonded Turntrans53.437.9172.1-58.8-50.2000114.6D462 G463 L488 Q491D459-D462 WeakPolarHBondContact O-CB 3.29Å; D459-D462 PolarHBondContact O-N 3.21Å; D459-G463 PolarHBondContact O-N 3.34Å; D459-L488 PolarHBondContact N-O 2.79Å; D459-Q491 HydrophobicContact CB-CG 4.43Å
460S97.9Very high96.5Very high0 Ų036.2 Ų36.20%018%0.183CC..Hα-helixtrans56.1-140.6174.4-45.40000112.5N428 I457 K458 D462 G463 L464 T490 Q491N428-S460 WeakPolarHBondContact O-CB 3.43Å; N428-S460 PolarHBondContact O-OG 2.97Å; I457-S460 WeakPolarHBondContact CG2-O 3.41Å; K458-S460 VanDerWaalsContact C-N 3.26Å; K458-S460 PolarHBondContact O-N 3.14Å; S460-D462 PolarHBondContact O-N 3.45Å; S460-G463 PolarHBondContact O-N 2.92Å; S460-L464 WeakPolarHBondContact O-CB 3.38Å; S460-L464 PolarHBondContact O-N 3.15Å; S460-T490 WeakPolarHBondContact OG-CA 3.1Å; S460-Q491 PolarHBondContact OG-N 3.44Å; S460-Q491 PolarHBondContact OG-O 3.24Å
461F98.2Very high97.1Very high0 Ų039.1 Ų39.10%020%0.199CC..Hα-helixtrans-65-26.2177.3-68.5-79.4000113.2M427 V429 L464 I465 S493 P495 V502 L516 S525 M529M427-F461 HydrophobicContact CE-CD1 4.02Å; M427-F461 HydrophobicContact CE-CD2 4.24Å; M427-F461 HydrophobicContact CE-CE1 3.41Å; M427-F461 VanDerWaalsContact CE-CE1 3.41Å; M427-F461 HydrophobicContact CE-CE2 3.67Å; M427-F461 HydrophobicContact CE-CG 4.41Å; M427-F461 HydrophobicContact CE-CZ 3.21Å; V429-F461 HydrophobicContact CG1-CD2 4.33Å; V429-F461 HydrophobicContact CG1-CE2 4.12Å; V429-F461 HydrophobicContact CG2-CD2 4.35Å; V429-F461 HydrophobicContact CG2-CE2 3.93Å; F461-L464 HydrophobicContact CD1-CD1 4.1Å; F461-L464 HydrophobicContact CE1-CD1 4.29Å; F461-L464 PolarHBondContact O-N 3.35Å; F461-I465 WeakPolarHBondContact O-CB 3.42Å; F461-I465 VanDerWaalsContact O-CD1 3.3Å; F461-I465 WeakPolarHBondContact O-CD1 3.46Å; F461-I465 WeakPolarHBondContact O-CG1 3.43Å; F461-I465 PolarHBondContact O-N 3.42Å; F461-S493 WeakPolarHBondContact CD2-O 3.31Å; F461-P495 HydrophobicContact CD1-CB 3.83Å; F461-P495 HydrophobicContact CE1-CB 3.59Å; F461-P495 HydrophobicContact CE1-CG 4.03Å; F461-P495 HydrophobicContact CZ-CB 4.13Å; F461-P495 HydrophobicContact CZ-CG 4.06Å; F461-V502 HydrophobicContact CD1-CG2 4.17Å; F461-L516 HydrophobicContact CZ-CD2 4.38Å; F461-S525 VanDerWaalsContact CE2-CB 3.48Å; F461-S525 VanDerWaalsContact CE2-OG 3.22Å; F461-S525 WeakPolarHBondContact CE2-OG 3.45Å; F461-M529 HydrophobicContact CE1-SD 4.3Å; F461-M529 HydrophobicContact CZ-CE 4.21Å
462D97.7Very high97.5Very high32 Ų3237.6 Ų37.617%0.17118%0.182CC..Hα-helixtrans-67.1-40.7178.6-67.7-46.6000112.1D459 S460 K466 S493 K497D459-D462 WeakPolarHBondContact O-CB 3.29Å; D459-D462 PolarHBondContact O-N 3.21Å; S460-D462 PolarHBondContact O-N 3.45Å; D462-K466 WeakPolarHBondContact O-CD 3.49Å; D462-K466 WeakPolarHBondContact O-CG 3.28Å; D462-S493 PolarHBondContact OD1-OG 3.45Å; D462-S493 WeakPolarHBondContact OD2-CB 3.44Å; D462-S493 PolarHBondContact OD2-OG 3.17Å; D462-K497 VanDerWaalsContact OD1-CD 3.31Å; D462-K497 WeakPolarHBondContact OD1-CD 3.44Å; D462-K497 WeakPolarHBondContact OD1-CE 3.44Å; D462-K497 IonicContact OD1-NZ 3.07Å; D462-K497 PolarHBondContact OD1-NZ 3.24Å
463G97.5Very high97.5Very high1 Ų141.8 Ų41.81%0.0120%0.204CC..Hα-helixtrans-79.9-29.917200000112.9K458 D459 S460 I465 K466 G467 C468K458-G463 WeakPolarHBondContact O-CA 3.39Å; D459-G463 PolarHBondContact O-N 3.34Å; S460-G463 PolarHBondContact O-N 2.92Å; G463-I465 PolarHBondContact O-N 2.9Å; G463-K466 CarbonylContact O-C 3.57Å; G463-K466 PolarHBondContact O-N 2.85Å; G463-K466 VanDerWaalsContact O-N 3.13Å; G463-G467 PolarHBondContact O-N 2.94Å; G463-C468 WeakPolarHBondContact O-CB 3.25Å; G463-C468 PolarHBondContact O-N 3.21Å
464L97.9Very high97Very high1 Ų136.9 Ų36.91%0.00519%0.186CC..Hα-helixtrans-55.3-52.4171.5-161.4164.2000110.8M427 I457 S460 F461 K466 G467 F469 V502 Q505M427-L464 HydrophobicContact CE-CD1 4.06Å; M427-L464 HydrophobicContact SD-CD1 4.17Å; I457-L464 HydrophobicContact CD1-CD1 3.89Å; I457-L464 HydrophobicContact CD1-CG 4.22Å; I457-L464 HydrophobicContact CG2-CB 3.74Å; I457-L464 HydrophobicContact CG2-CG 4.24Å; S460-L464 WeakPolarHBondContact O-CB 3.38Å; S460-L464 PolarHBondContact O-N 3.15Å; F461-L464 HydrophobicContact CD1-CD1 4.1Å; F461-L464 HydrophobicContact CE1-CD1 4.29Å; F461-L464 PolarHBondContact O-N 3.35Å; L464-K466 PolarHBondContact O-N 3.17Å; L464-G467 PolarHBondContact O-N 3.38Å; L464-F469 HydrophobicContact CG-CE2 4.35Å; L464-F469 HydrophobicContact CG-CZ 4.22Å; L464-V502 HydrophobicContact CD1-CG1 4.24Å; L464-V502 HydrophobicContact CD2-CB 3.99Å; L464-V502 HydrophobicContact CD2-CG1 3.85Å; L464-V502 HydrophobicContact CD2-CG2 4.03Å; L464-Q505 HydrophobicContact CD2-CB 3.9Å; L464-Q505 WeakPolarHBondContact O-CG 3.43Å
465I97.9Very high96.4Very high27 Ų2740 Ų4014%0.13820%0.2CC..Hα-helixtrans-56.1-35.7178.6-71.1162.8000111.3F461 G463 G467 K497 N498 Q501 V502F461-I465 WeakPolarHBondContact O-CB 3.42Å; F461-I465 VanDerWaalsContact O-CD1 3.3Å; F461-I465 WeakPolarHBondContact O-CD1 3.46Å; F461-I465 WeakPolarHBondContact O-CG1 3.43Å; F461-I465 PolarHBondContact O-N 3.42Å; G463-I465 PolarHBondContact O-N 2.9Å; I465-G467 VanDerWaalsContact C-N 3.34Å; I465-K497 HydrophobicContact CD1-CB 4.29Å; I465-K497 HydrophobicContact CD1-CG 4.43Å; I465-N498 HydrophobicContact CD1-CB 3.72Å; I465-N498 HydrophobicContact CG1-CB 4.08Å; I465-N498 HydrophobicContact CG2-CB 4.22Å; I465-Q501 HydrophobicContact CB-CG 4.24Å; I465-Q501 HydrophobicContact CG2-CB 4.1Å; I465-Q501 HydrophobicContact CG2-CG 3.73Å; I465-Q501 WeakPolarHBondContact O-CG 3.33Å; I465-Q501 PolarHBondContact O-NE2 2.82Å; I465-Q501 VanDerWaalsContact O-NE2 3.13Å; I465-V502 HydrophobicContact CD1-CG2 4.45Å; I465-V502 HydrophobicContact CG1-CG2 3.87Å
466K97.2Very high96Very high162 Ų16241.1 Ų41.170%0.70421%0.208SC*.THydrogen-bonded Turntrans-83.2-4.5178.9-65.8172.8-173.9175.90114D462 G463 L464D462-K466 WeakPolarHBondContact O-CD 3.49Å; D462-K466 WeakPolarHBondContact O-CG 3.28Å; G463-K466 CarbonylContact O-C 3.57Å; G463-K466 PolarHBondContact O-N 2.85Å; G463-K466 VanDerWaalsContact O-N 3.13Å; L464-K466 PolarHBondContact O-N 3.17Å
467G96.3Very high95.7Very high22 Ų2241.1 Ų41.123%0.22721%0.208CC..THydrogen-bonded Turntrans74.326-175.800000114.2G463 L464 I465 F469G463-G467 PolarHBondContact O-N 2.94Å; L464-G467 PolarHBondContact O-N 3.38Å; I465-G467 VanDerWaalsContact C-N 3.34Å; G467-F469 VanDerWaalsContact C-N 3.27Å; G467-F469 PolarHBondContact O-N 3.3Å
468C97.7Very high95.2Very high49 Ų4942.4 Ų42.433%0.33122%0.216SC..  trans-78.765.5-178.6-60.20000113.2K458 G463K458-C468 HydrophobicContact CB-CB 4.22Å; K458-C468 PolarHBondContact N-O 3.17Å; G463-C468 WeakPolarHBondContact O-CB 3.25Å; G463-C468 PolarHBondContact O-N 3.21Å
469F97.9Very high94.6Very high32 Ų3239.1 Ų39.114%0.1420%0.203CC..EExtended strand (participates in β ladder)trans-94.8142.2176.7-71.6-115.9000110.8A425 Y455 A456 I457 L464 G467 Q505 F509 I511A425-F469 HydrophobicContact CB-CE1 4.47Å; Y455-F469 HydrophobicContact CD1-CB 4.04Å; Y455-F469 HydrophobicContact CD1-CD1 4.33Å; Y455-F469 HydrophobicContact CG-CD1 4.01Å; A456-F469 CarbonylContact O-C 3.48Å; A456-F469 WeakPolarHBondContact O-CA 3.47Å; I457-F469 HydrophobicContact CD1-CE1 3.87Å; I457-F469 HydrophobicContact CD1-CZ 3.92Å; I457-F469 HydrophobicContact CG1-CD1 3.83Å; I457-F469 HydrophobicContact CG1-CE1 3.49Å; I457-F469 VanDerWaalsContact CG1-CE1 3.49Å; I457-F469 HydrophobicContact CG1-CE2 4.22Å; I457-F469 HydrophobicContact CG1-CG 4.32Å; I457-F469 HydrophobicContact CG1-CZ 3.7Å; L464-F469 HydrophobicContact CG-CE2 4.35Å; L464-F469 HydrophobicContact CG-CZ 4.22Å; G467-F469 VanDerWaalsContact C-N 3.27Å; G467-F469 PolarHBondContact O-N 3.3Å; F469-Q505 HydrophobicContact CE2-CB 4.3Å; F469-F509 HydrophobicContact CB-CD1 4.18Å; F469-F509 HydrophobicContact CB-CE1 3.71Å; F469-F509 HydrophobicContact CB-CE2 4.17Å; F469-F509 HydrophobicContact CB-CZ 3.71Å; F469-F509 HydrophobicContact CD1-CB 4.33Å; F469-F509 HydrophobicContact CD1-CD1 4.11Å; F469-F509 AromaticContact CD1-CD2 3.98Å; F469-F509 HydrophobicContact CD1-CD2 3.98Å; F469-F509 HydrophobicContact CD1-CE1 4.44Å; F469-F509 HydrophobicContact CD1-CE2 4.33Å; F469-F509 AromaticContact CD1-CG 3.87Å; F469-F509 HydrophobicContact CD1-CG 3.87Å; F469-F509 AromaticContact CD2-CD2 3.64Å; F469-F509 HydrophobicContact CD2-CD2 3.64Å; F469-F509 HydrophobicContact CD2-CE1 4.41Å; F469-F509 AromaticContact CD2-CE2 3.33Å; F469-F509 HydrophobicContact CD2-CE2 3.33Å; F469-F509 HydrophobicContact CD2-CG 4.32Å; F469-F509 AromaticContact CD2-CZ 3.77Å; F469-F509 HydrophobicContact CD2-CZ 3.77Å; F469-F509 HydrophobicContact CE1-CB 4.2Å; F469-F509 HydrophobicContact CE1-CD2 4.03Å; F469-F509 HydrophobicContact CE1-CG 4.08Å; F469-F509 AromaticContact CE2-CD2 3.69Å; F469-F509 HydrophobicContact CE2-CD2 3.69Å; F469-F509 AromaticContact CE2-CE2 3.73Å; F469-F509 HydrophobicContact CE2-CE2 3.73Å; F469-F509 HydrophobicContact CG-CD1 4.09Å; F469-F509 AromaticContact CG-CD2 3.83Å; F469-F509 HydrophobicContact CG-CD2 3.83Å; F469-F509 AromaticContact CG-CE1 3.97Å; F469-F509 HydrophobicContact CG-CE1 3.97Å; F469-F509 AromaticContact CG-CE2 3.7Å; F469-F509 HydrophobicContact CG-CE2 3.7Å; F469-F509 HydrophobicContact CG-CG 4.03Å; F469-F509 AromaticContact CG-CZ 3.78Å; F469-F509 HydrophobicContact CG-CZ 3.78Å; F469-F509 AromaticContact CZ-CD2 3.89Å; F469-F509 HydrophobicContact CZ-CD2 3.89Å; F469-F509 HydrophobicContact CZ-CE2 4.39Å; F469-F509 HydrophobicContact CZ-CG 4.4Å; F469-I511 HydrophobicContact CE1-CD1 4.18Å; F469-I511 HydrophobicContact CE1-CG1 4.34Å
470K97.9Very high94.4Very high75 Ų7537.4 Ų37.433%0.32619%0.191SC..EExtended strand (participates in β ladder)trans-118.7123.6167.6178.6-178.6172.9-173.40108.6Y455 A456 M472 D476Y455-K470 CarbonylContact C-O 3.58Å; Y455-K470 WeakPolarHBondContact CA-O 3.48Å; A456-K470 PolarHBondContact N-O 2.89Å; A456-K470 PolarHBondContact O-N 3.4Å; K470-M472 HydrophobicContact CB-SD 4.31Å; K470-M472 HydrophobicContact CD-SD 3.8Å; K470-M472 HydrophobicContact CG-SD 3.93Å; K470-M472 PolarHBondContact O-N 2.82Å; K470-D476 WeakPolarHBondContact CE-OD1 3.26Å; K470-D476 WeakPolarHBondContact CE-OD2 3.42Å; K470-D476 IonicContact NZ-OD1 3.21Å; K470-D476 PolarHBondContact NZ-OD1 3.31Å; K470-D476 IonicContact NZ-OD2 3.89Å
471D97.9Very high94.1Very high72 Ų7237.5 Ų37.539%0.38519%0.192SC..EExtended strand (participates in β ladder)trans-68.4125.8169.4-162.513.3000108.7R453 Y455R453-D471 IonicContact CZ-OD1 2.62Å; R453-D471 IonicContact CZ-OD2 2.73Å; R453-D471 VanDerWaalsContact CZ-OD2 3.29Å; R453-D471 IonicContact NE-OD1 3.99Å; R453-D471 PolarHBondContact NE-OD1 3.22Å; R453-D471 VanDerWaalsContact NE-OD1 3.09Å; R453-D471 IonicContact NE-OD2 3.42Å; R453-D471 PolarHBondContact NE-OD2 3.29Å; R453-D471 VanDerWaalsContact NE-OD2 3.1Å; R453-D471 IonicContact NH2-OD1 3.98Å; R453-D471 IonicContact NH2-OD2 2.8Å; R453-D471 PolarHBondContact NH2-OD2 2.65Å; Y455-D471 HydrophobicContact CD1-CB 4.12Å; Y455-D471 HydrophobicContact CE1-CB 3.75Å
472M96.8Very high93.7Very high6 Ų638.5 Ų38.53%0.0320%0.197CC..PPolyproline II helixtrans-102.4126.4-170.2-61.3-63.1-68.400110.8V444 V454 A456 K470 D476 V477 W480V444-M472 HydrophobicContact CG1-CB 3.97Å; V444-M472 HydrophobicContact CG2-CB 4.28Å; V444-M472 HydrophobicContact CG2-CE 4.35Å; V444-M472 HydrophobicContact CG2-CG 4.36Å; V454-M472 HydrophobicContact CB-CB 4.37Å; V454-M472 WeakPolarHBondContact O-CB 3.37Å; V454-M472 PolarHBondContact O-N 3.17Å; A456-M472 HydrophobicContact CB-CE 4.32Å; A456-M472 HydrophobicContact CB-CG 3.61Å; A456-M472 HydrophobicContact CB-SD 3.44Å; A456-M472 WeakPolarHBondContact CB-SD 3.18Å; K470-M472 HydrophobicContact CB-SD 4.31Å; K470-M472 HydrophobicContact CD-SD 3.8Å; K470-M472 HydrophobicContact CG-SD 3.93Å; K470-M472 PolarHBondContact O-N 2.82Å; M472-D476 HydrophobicContact CE-CB 3.69Å; M472-D476 HydrophobicContact SD-CB 4.43Å; M472-V477 HydrophobicContact CE-CG1 3.44Å; M472-V477 VanDerWaalsContact CE-CG1 3.44Å; M472-W480 HydrophobicContact CE-CH2 4.38Å
473D92Very high93.5Very high93 Ų9341.3 Ų41.350%0.49721%0.208SC..PPolyproline II helixtrans-101.1166.8169.1-170.324.9000111.5H475 D476D473-H475 PolarHBondContact O-N 3.12Å; D473-H475 VanDerWaalsContact O-N 3.09Å; D473-H475 IonicContact OD2-ND1 3.26Å; D473-D476 PolarHBondContact N-OD2 2.82Å; D473-D476 WeakPolarHBondContact O-CB 3.39Å; D473-D476 PolarHBondContact O-N 3.42Å; D473-D476 VanDerWaalsContact O-N 3.13Å
474W86.3Confident93.4Very high11 Ų1142 Ų424%0.04222%0.215CC..THydrogen-bonded Turntrans-52.5-34-178.9-171.4-90.5000113.7K406 I407 P409 R445 L448K406-W474 WeakPolarHBondContact O-CZ2 3.45Å; I407-W474 PolarHBondContact O-NE1 2.68Å; P409-W474 HydrophobicContact CG-CE3 4.2Å; P409-W474 HydrophobicContact CG-CZ3 4.29Å; R445-W474 HydrophobicContact CB-CE3 4.35Å; R445-W474 HydrophobicContact CB-CH2 3.96Å; R445-W474 HydrophobicContact CB-CZ2 4.32Å; R445-W474 HydrophobicContact CB-CZ3 3.99Å; R445-W474 HydrophobicContact CG-CD2 4.07Å; R445-W474 HydrophobicContact CG-CE3 4.15Å; R445-W474 HydrophobicContact CG-CH2 4.15Å; R445-W474 HydrophobicContact CG-CZ2 4.05Å; R445-W474 HydrophobicContact CG-CZ3 4.22Å; R445-W474 WeakPolarHBondContact O-CZ3 3.09Å; L448-W474 HydrophobicContact CB-CE3 4.19Å; L448-W474 HydrophobicContact CD1-CB 4.32Å; L448-W474 HydrophobicContact CD1-CE3 4.4Å
475H86Confident93.2Very high64 Ų6443.3 Ų43.330%0.29623%0.228SC..THydrogen-bonded Turntrans-89.4-16.1-174.6-57.189.1000113.7H269 D473 V477 T478H269-H475 WeakPolarHBondContact CB-NE2 3.41Å; H269-H475 AromaticContact CD2-CE1 3.89Å; H269-H475 AromaticContact CG-NE2 3.85Å; H269-H475 PolarHBondContact O-CD2 2.73Å; D473-H475 PolarHBondContact O-N 3.12Å; D473-H475 VanDerWaalsContact O-N 3.09Å; D473-H475 IonicContact OD2-ND1 3.26Å; H475-V477 PolarHBondContact O-N 2.9Å; H475-T478 WeakPolarHBondContact O-CB 3.16Å; H475-T478 PolarHBondContact O-N 3.49Å; H475-T478 PolarHBondContact O-OG1 3.03Å; H475-T478 VanDerWaalsContact O-OG1 3.05Å
476D91Very high93.2Very high51 Ų5143.2 Ų43.227%0.27323%0.23SC..THydrogen-bonded Turntrans-64.6-24.4-177.1-82-45.8000113.3K470 M472 D473 W480K470-D476 WeakPolarHBondContact CE-OD1 3.26Å; K470-D476 WeakPolarHBondContact CE-OD2 3.42Å; K470-D476 IonicContact NZ-OD1 3.21Å; K470-D476 PolarHBondContact NZ-OD1 3.31Å; K470-D476 IonicContact NZ-OD2 3.89Å; M472-D476 HydrophobicContact CE-CB 3.69Å; M472-D476 HydrophobicContact SD-CB 4.43Å; D473-D476 PolarHBondContact N-OD2 2.82Å; D473-D476 WeakPolarHBondContact O-CB 3.39Å; D473-D476 PolarHBondContact O-N 3.42Å; D473-D476 VanDerWaalsContact O-N 3.13Å; D476-W480 VanDerWaalsContact O-CE2 3.27Å; D476-W480 WeakPolarHBondContact O-CZ2 3.47Å; D476-W480 PolarHBondContact O-NE1 2.76Å
477V92Very high93.2Very high0 Ų040.1 Ų40.10%022%0.217CC..THydrogen-bonded Turntrans-10812.6-175.5-64.40000113.6V440 R441 V444 R445 M472 H475 W480V440-V477 HydrophobicContact CG1-CG1 4.38Å; R441-V477 HydrophobicContact CB-CB 3.89Å; R441-V477 HydrophobicContact CB-CG2 4.2Å; R441-V477 WeakPolarHBondContact CD-O 3.24Å; R441-V477 HydrophobicContact CG-CB 3.98Å; R441-V477 HydrophobicContact CG-CG2 3.85Å; R441-V477 WeakPolarHBondContact CG-O 3.43Å; V444-V477 HydrophobicContact CB-CG1 4.14Å; V444-V477 HydrophobicContact CB-CG2 4.22Å; V444-V477 HydrophobicContact CG1-CG1 4.21Å; V444-V477 HydrophobicContact CG1-CG2 4.06Å; V444-V477 HydrophobicContact CG2-CG1 4.07Å; R445-V477 HydrophobicContact CG-CG2 4.17Å; M472-V477 HydrophobicContact CE-CG1 3.44Å; M472-V477 VanDerWaalsContact CE-CG1 3.44Å; H475-V477 PolarHBondContact O-N 2.9Å; V477-W480 VanDerWaalsContact C-CD1 3.44Å; V477-W480 HydrophobicContact CB-CD2 4.16Å; V477-W480 HydrophobicContact CB-CG 4.28Å; V477-W480 HydrophobicContact CG1-CD2 4.16Å; V477-W480 HydrophobicContact CG1-CE3 4.16Å; V477-W480 HydrophobicContact CG1-CH2 4.46Å; V477-W480 HydrophobicContact CG1-CZ2 4.45Å; V477-W480 HydrophobicContact CG1-CZ3 4.33Å; V477-W480 WeakPolarHBondContact O-CB 3.4Å; V477-W480 PolarHBondContact O-N 3.19Å
478T86.5Confident93.2Very high27 Ų2739.4 Ų39.417%0.16621%0.208CC..THydrogen-bonded Turntrans-65.4133179.4-64.20000111.2H475 W480H475-T478 WeakPolarHBondContact O-CB 3.16Å; H475-T478 PolarHBondContact O-N 3.49Å; H475-T478 PolarHBondContact O-OG1 3.03Å; H475-T478 VanDerWaalsContact O-OG1 3.05Å; T478-W480 PolarHBondContact O-N 3.43Å
479N86.3Confident93.2Very high28 Ų2838 Ų3815%0.1520%0.201CC..THydrogen-bonded Turntrans63.121-178.6-51.6-43.5000114.6Q209 Q213 E240 M482 F483Q209-N479 PolarHBondContact NE2-OD1 3.49Å; Q213-N479 PolarHBondContact NE2-ND2 3.37Å; E240-N479 WeakPolarHBondContact OE1-CA 3.45Å; E240-N479 PolarHBondContact OE1-N 2.67Å; E240-N479 PolarHBondContact OE2-N 2.8Å; N479-M482 HydrophobicContact CB-CE 3.8Å; N479-F483 VanDerWaalsContact O-CD2 3.31Å; N479-F483 WeakPolarHBondContact O-CD2 3.29Å; N479-F483 WeakPolarHBondContact O-CE2 3.17Å
480W92.7Very high93.2Very high32 Ų3237.4 Ų37.412%0.12120%0.2CC..  trans-75.6-24.9176.9-80.834.1000112.3E240 N437 V440 R441 M472 D476 V477 T478 M482 F483 F487 L488E240-W480 PolarHBondContact OE1-N 3.19Å; N437-W480 HydrophobicContact CB-CB 4.13Å; N437-W480 HydrophobicContact CB-CE3 4.3Å; N437-W480 WeakPolarHBondContact CB-O 3Å; V440-W480 HydrophobicContact CB-CE3 4.29Å; V440-W480 HydrophobicContact CB-CZ3 4.19Å; V440-W480 HydrophobicContact CG1-CE3 4.13Å; V440-W480 HydrophobicContact CG1-CZ3 3.7Å; R441-W480 HydrophobicContact CB-CB 4.18Å; M472-W480 HydrophobicContact CE-CH2 4.38Å; D476-W480 VanDerWaalsContact O-CE2 3.27Å; D476-W480 WeakPolarHBondContact O-CZ2 3.47Å; D476-W480 PolarHBondContact O-NE1 2.76Å; V477-W480 VanDerWaalsContact C-CD1 3.44Å; V477-W480 HydrophobicContact CB-CD2 4.16Å; V477-W480 HydrophobicContact CB-CG 4.28Å; V477-W480 HydrophobicContact CG1-CD2 4.16Å; V477-W480 HydrophobicContact CG1-CE3 4.16Å; V477-W480 HydrophobicContact CG1-CH2 4.46Å; V477-W480 HydrophobicContact CG1-CZ2 4.45Å; V477-W480 HydrophobicContact CG1-CZ3 4.33Å; V477-W480 WeakPolarHBondContact O-CB 3.4Å; V477-W480 PolarHBondContact O-N 3.19Å; T478-W480 PolarHBondContact O-N 3.43Å; W480-M482 PolarHBondContact O-N 3.13Å; W480-F483 PolarHBondContact O-N 3.26Å; W480-F487 HydrophobicContact CB-CE2 4.46Å; W480-F487 AromaticContact CD1-CD2 3.91Å; W480-F487 AromaticContact CD1-CE2 3.9Å; W480-F487 AromaticContact CD2-CD2 3.49Å; W480-F487 HydrophobicContact CD2-CD2 3.49Å; W480-F487 VanDerWaalsContact CD2-CD2 3.49Å; W480-F487 HydrophobicContact CD2-CE2 4.18Å; W480-F487 HydrophobicContact CD2-CG 4.5Å; W480-F487 AromaticContact CE2-CD2 3.54Å; W480-F487 HydrophobicContact CE3-CB 4.27Å; W480-F487 AromaticContact CE3-CD2 3.89Å; W480-F487 HydrophobicContact CE3-CD2 3.89Å; W480-F487 AromaticContact CG-CD2 3.75Å; W480-F487 HydrophobicContact CG-CD2 3.75Å; W480-F487 AromaticContact CG-CE2 3.94Å; W480-F487 HydrophobicContact CG-CE2 3.94Å; W480-F487 HydrophobicContact CH2-CB 3.74Å; W480-F487 HydrophobicContact CH2-CD2 4.39Å; W480-F487 HydrophobicContact CZ2-CB 4Å; W480-F487 HydrophobicContact CZ2-CD2 4.04Å; W480-F487 HydrophobicContact CZ3-CB 3.87Å; W480-F487 HydrophobicContact CZ3-CD2 4.31Å; W480-F487 AromaticContact NE1-CD2 3.81Å; W480-L488 HydrophobicContact CH2-CD2 3.81Å; W480-L488 HydrophobicContact CH2-CG 4.47Å; W480-L488 HydrophobicContact CZ3-CD2 4.08Å; W480-L488 HydrophobicContact CZ3-CG 4.28Å
481S91.6Very high93.1Very high3 Ų337.9 Ų37.92%0.02120%0.203CC..THydrogen-bonded Turntrans-64.3-28.1-172.777.30000113.7A238 E240 F483 P689 R694A238-S481 PolarHBondContact O-OG 2.98Å; A238-S481 VanDerWaalsContact O-OG 3.04Å; E240-S481 VanDerWaalsContact CG-OG 3.28Å; E240-S481 WeakPolarHBondContact CG-OG 3.24Å; E240-S481 WeakPolarHBondContact OE1-CB 3.38Å; E240-S481 PolarHBondContact OE1-N 2.6Å; E240-S481 PolarHBondContact OE1-OG 3.35Å; E240-S481 VanDerWaalsContact OE1-OG 3.05Å; S481-F483 VanDerWaalsContact C-N 3.34Å; S481-P689 WeakPolarHBondContact O-CG 3.38Å; S481-R694 WeakPolarHBondContact O-CD 3.09Å; S481-R694 WeakPolarHBondContact O-CG 3.23Å
482M91.2Very high93Very high21 Ų2140.5 Ų40.510%0.10321%0.211CC..THydrogen-bonded Turntrans-81.4-10.3-174.269-175.8173.300114.7Q209 N479 W480 P689Q209-M482 VanDerWaalsContact CD-SD 3.54Å; Q209-M482 HydrophobicContact CG-SD 4.37Å; Q209-M482 PolarHBondContact OE1-SD 3.15Å; N479-M482 HydrophobicContact CB-CE 3.8Å; W480-M482 PolarHBondContact O-N 3.13Å; M482-P689 WeakPolarHBondContact O-CD 3.38Å
483F93.4Very high93Very high91 Ų9141 Ų4140%0.39922%0.216SC..  trans-105.1135.1-176-63.2-74.4000112.1N437 N479 W480 S481 F487N437-F483 PolarHBondContact ND2-O 2.57Å; N479-F483 VanDerWaalsContact O-CD2 3.31Å; N479-F483 WeakPolarHBondContact O-CD2 3.29Å; N479-F483 WeakPolarHBondContact O-CE2 3.17Å; W480-F483 PolarHBondContact O-N 3.26Å; S481-F483 VanDerWaalsContact C-N 3.34Å; F483-F487 HydrophobicContact CB-CE1 4.3Å; F483-F487 HydrophobicContact CB-CE2 4.2Å; F483-F487 HydrophobicContact CB-CZ 3.63Å; F483-F487 HydrophobicContact CD1-CZ 4.44Å; F483-F487 AromaticContact CD2-CE2 3.83Å; F483-F487 HydrophobicContact CD2-CE2 3.83Å; F483-F487 AromaticContact CD2-CZ 3.49Å; F483-F487 HydrophobicContact CD2-CZ 3.49Å; F483-F487 VanDerWaalsContact CD2-CZ 3.49Å; F483-F487 HydrophobicContact CE2-CZ 4.18Å; F483-F487 HydrophobicContact CG-CE2 4.29Å; F483-F487 AromaticContact CG-CZ 3.62Å; F483-F487 HydrophobicContact CG-CZ 3.62Å
484G94Very high93.2Very high15 Ų1538.5 Ų38.516%0.15520%0.202CC..  trans-73.4-172.3164.500000112.1N437 G687N437-G484 PolarHBondContact ND2-O 3.25Å; G484-G687 WeakPolarHBondContact CA-O 3.31Å; G484-G687 PolarHBondContact N-O 3.28Å
485G95Very high93.7Very high28 Ų2838 Ų3829%0.28920%0.2SC..SBendtrans69.9-154.1-176.800000113.4N437N437-G485 PolarHBondContact ND2-O 3.29Å
486S97Very high94.2Very high25 Ų2539 Ų3918%0.17521%0.211CC..  trans-141.3113.9-179.7175.90000110.8N428 N437 L488 G489N428-S486 PolarHBondContact ND2-OG 3.46Å; N437-S486 WeakPolarHBondContact OD1-CA 3.21Å; S486-L488 VanDerWaalsContact C-N 3.27Å; S486-L488 PolarHBondContact O-N 3.32Å; S486-L488 PolarHBondContact OG-N 2.92Å; S486-G489 PolarHBondContact O-N 2.83Å; S486-G489 VanDerWaalsContact O-N 3.13Å; S486-G489 VanDerWaalsContact OG-C 3.25Å; S486-G489 PolarHBondContact OG-N 3.3Å; S486-G489 PolarHBondContact OG-O 3.48Å
487F97.1Very high94.5Very high98 Ų9843.1 Ų43.143%0.4323%0.226SC..THydrogen-bonded Turntrans-73.1-19.6173.9-67.6-25.6000113.8N437 W480 F483N437-F487 PolarHBondContact OD1-N 3.14Å; W480-F487 HydrophobicContact CB-CE2 4.46Å; W480-F487 AromaticContact CD1-CD2 3.91Å; W480-F487 AromaticContact CD1-CE2 3.9Å; W480-F487 AromaticContact CD2-CD2 3.49Å; W480-F487 HydrophobicContact CD2-CD2 3.49Å; W480-F487 VanDerWaalsContact CD2-CD2 3.49Å; W480-F487 HydrophobicContact CD2-CE2 4.18Å; W480-F487 HydrophobicContact CD2-CG 4.5Å; W480-F487 AromaticContact CE2-CD2 3.54Å; W480-F487 HydrophobicContact CE3-CB 4.27Å; W480-F487 AromaticContact CE3-CD2 3.89Å; W480-F487 HydrophobicContact CE3-CD2 3.89Å; W480-F487 AromaticContact CG-CD2 3.75Å; W480-F487 HydrophobicContact CG-CD2 3.75Å; W480-F487 AromaticContact CG-CE2 3.94Å; W480-F487 HydrophobicContact CG-CE2 3.94Å; W480-F487 HydrophobicContact CH2-CB 3.74Å; W480-F487 HydrophobicContact CH2-CD2 4.39Å; W480-F487 HydrophobicContact CZ2-CB 4Å; W480-F487 HydrophobicContact CZ2-CD2 4.04Å; W480-F487 HydrophobicContact CZ3-CB 3.87Å; W480-F487 HydrophobicContact CZ3-CD2 4.31Å; W480-F487 AromaticContact NE1-CD2 3.81Å; F483-F487 HydrophobicContact CB-CE1 4.3Å; F483-F487 HydrophobicContact CB-CE2 4.2Å; F483-F487 HydrophobicContact CB-CZ 3.63Å; F483-F487 HydrophobicContact CD1-CZ 4.44Å; F483-F487 AromaticContact CD2-CE2 3.83Å; F483-F487 HydrophobicContact CD2-CE2 3.83Å; F483-F487 AromaticContact CD2-CZ 3.49Å; F483-F487 HydrophobicContact CD2-CZ 3.49Å; F483-F487 VanDerWaalsContact CD2-CZ 3.49Å; F483-F487 HydrophobicContact CE2-CZ 4.18Å; F483-F487 HydrophobicContact CG-CE2 4.29Å; F483-F487 AromaticContact CG-CZ 3.62Å; F483-F487 HydrophobicContact CG-CZ 3.62Å
488L97.4Very high94.7Very high7 Ų746.4 Ų46.44%0.03724%0.244CC..THydrogen-bonded Turntrans-79.5-7.8170.1-59.1-170.7000112.3V440 A456 K458 D459 W480 S486V440-L488 HydrophobicContact CG1-CD1 4.06Å; V440-L488 HydrophobicContact CG2-CD1 3.81Å; V440-L488 HydrophobicContact CG2-CG 4.42Å; A456-L488 HydrophobicContact CB-CD1 3.97Å; A456-L488 HydrophobicContact CB-CD2 3.61Å; A456-L488 HydrophobicContact CB-CG 4.46Å; K458-L488 CarbonylContact C-O 3.53Å; K458-L488 WeakPolarHBondContact CA-O 3.34Å; D459-L488 PolarHBondContact N-O 2.79Å; W480-L488 HydrophobicContact CH2-CD2 3.81Å; W480-L488 HydrophobicContact CH2-CG 4.47Å; W480-L488 HydrophobicContact CZ3-CD2 4.08Å; W480-L488 HydrophobicContact CZ3-CG 4.28Å; S486-L488 VanDerWaalsContact C-N 3.27Å; S486-L488 PolarHBondContact O-N 3.32Å; S486-L488 PolarHBondContact OG-N 2.92Å
489G97.2Very high95.1Very high18 Ų1846.4 Ų46.419%0.18624%0.242CC..  trans72.6161-160.900000110.8S486S486-G489 PolarHBondContact O-N 2.83Å; S486-G489 VanDerWaalsContact O-N 3.13Å; S486-G489 VanDerWaalsContact OG-C 3.25Å; S486-G489 PolarHBondContact OG-N 3.3Å; S486-G489 PolarHBondContact OG-O 3.48Å
490T97.7Very high95.6Very high20 Ų2052.3 Ų52.312%0.12327%0.269CS..  trans-155.3133176.3-175.30000109.7G430 P432 M436 S460G430-T490 PolarHBondContact N-OG1 2.8Å; G430-T490 WeakPolarHBondContact O-CG2 3.4Å; G430-T490 PolarHBondContact O-OG1 3.46Å; P432-T490 HydrophobicContact CB-CG2 3.89Å; P432-T490 HydrophobicContact CG-CG2 4.41Å; M436-T490 HydrophobicContact SD-CG2 4.36Å; S460-T490 WeakPolarHBondContact OG-CA 3.1Å
491Q96.9Very high95.8Very high85 Ų8554 Ų5440%0.39728%0.278SS..  trans-131157.3-177.5-57.6-60.4-20.900109.9G430 D459 S460 S493G430-Q491 PolarHBondContact N-O 2.86Å; D459-Q491 HydrophobicContact CB-CG 4.43Å; S460-Q491 PolarHBondContact OG-N 3.44Å; S460-Q491 PolarHBondContact OG-O 3.24Å; Q491-S493 VanDerWaalsContact C-N 3.26Å; Q491-S493 PolarHBondContact O-N 3.32Å
492K95.8Very high96.1Very high127 Ų12753.8 Ų53.855%0.55228%0.277SS*.  trans-86.77.4177.1-62.9-179-178.1175.40113.4E521K492-E521 HydrophobicContact CB-CG 4.25Å
493S95.8Very high96.4Very high17 Ų1753 Ų5312%0.11927%0.274CS..  trans-65.8142.6-179.541.30000111F461 D462 Q491F461-S493 WeakPolarHBondContact CD2-O 3.31Å; D462-S493 PolarHBondContact OD1-OG 3.45Å; D462-S493 WeakPolarHBondContact OD2-CB 3.44Å; D462-S493 PolarHBondContact OD2-OG 3.17Å; Q491-S493 VanDerWaalsContact C-N 3.26Å; Q491-S493 PolarHBondContact O-N 3.32Å
494L97Very high96.7Very high40 Ų4050.4 Ų50.421%0.20927%0.269CS..  trans-100.9159.1176-64-179.8000110T496 K497 E521 S525 I528L494-T496 PolarHBondContact O-N 3.19Å; L494-T496 VanDerWaalsContact O-N 3.12Å; L494-K497 WeakPolarHBondContact O-CB 3.35Å; L494-K497 PolarHBondContact O-N 3.22Å; L494-K497 VanDerWaalsContact O-N 3.11Å; L494-E521 HydrophobicContact CD2-CB 4.17Å; L494-E521 HydrophobicContact CD2-CG 4.44Å; L494-S525 WeakPolarHBondContact CD2-OG 3.33Å; L494-I528 HydrophobicContact CD1-CD1 4.23Å
495P97Very high96.9Very high0 Ų051 Ų510%027%0.267CS..G310 helixtrans-59.2-24.5176.820.6-31.6000113.2F461 K497 N498 M499 S525 I528 M529F461-P495 HydrophobicContact CD1-CB 3.83Å; F461-P495 HydrophobicContact CE1-CB 3.59Å; F461-P495 HydrophobicContact CE1-CG 4.03Å; F461-P495 HydrophobicContact CZ-CB 4.13Å; F461-P495 HydrophobicContact CZ-CG 4.06Å; P495-K497 PolarHBondContact O-N 3.47Å; P495-K497 VanDerWaalsContact O-N 3.11Å; P495-N498 CarbonylContact O-C 3.56Å; P495-N498 PolarHBondContact O-N 2.89Å; P495-M499 HydrophobicContact CB-CE 4.1Å; P495-M499 HydrophobicContact CB-SD 4.14Å; P495-M499 HydrophobicContact CG-CE 4.5Å; P495-M499 PolarHBondContact O-N 2.95Å; P495-S525 VanDerWaalsContact CD-OG 3.27Å; P495-S525 WeakPolarHBondContact CD-OG 3.04Å; P495-I528 HydrophobicContact CG-CB 4.31Å; P495-I528 HydrophobicContact CG-CG2 4.06Å; P495-M529 HydrophobicContact CB-CG 4.4Å; P495-M529 HydrophobicContact CG-CG 4.2Å
496T96.4Very high97Very high86 Ų8649.9 Ų49.953%0.52826%0.255SS..G310 helixtrans-61.7-16.217750.60000114.1L494 N498 M499 I528L494-T496 PolarHBondContact O-N 3.19Å; L494-T496 VanDerWaalsContact O-N 3.12Å; T496-N498 VanDerWaalsContact C-N 3.3Å; T496-N498 PolarHBondContact O-N 2.98Å; T496-M499 HydrophobicContact CG2-CE 3.86Å; T496-I528 HydrophobicContact CG2-CD1 4.14Å; T496-I528 HydrophobicContact CG2-CG2 3.98Å
497K95.4Very high97Very high137 Ų13755.7 Ų55.760%0.59627%0.273SS*.G310 helixtrans-59.1-39.9176.4-173.1173.9-178.6176.50112.7D462 I465 L494 P495D462-K497 VanDerWaalsContact OD1-CD 3.31Å; D462-K497 WeakPolarHBondContact OD1-CD 3.44Å; D462-K497 WeakPolarHBondContact OD1-CE 3.44Å; D462-K497 IonicContact OD1-NZ 3.07Å; D462-K497 PolarHBondContact OD1-NZ 3.24Å; I465-K497 HydrophobicContact CD1-CB 4.29Å; I465-K497 HydrophobicContact CD1-CG 4.43Å; L494-K497 WeakPolarHBondContact O-CB 3.35Å; L494-K497 PolarHBondContact O-N 3.22Å; L494-K497 VanDerWaalsContact O-N 3.11Å; P495-K497 PolarHBondContact O-N 3.47Å; P495-K497 VanDerWaalsContact O-N 3.11Å
498N96.5Very high97.1Very high69 Ų6957.5 Ų57.537%0.36928%0.282SS..SBendtrans-158.482.1170.7-170.9-23.7000109.8I465 P495 T496 E500 Q501 V502I465-N498 HydrophobicContact CD1-CB 3.72Å; I465-N498 HydrophobicContact CG1-CB 4.08Å; I465-N498 HydrophobicContact CG2-CB 4.22Å; P495-N498 CarbonylContact O-C 3.56Å; P495-N498 PolarHBondContact O-N 2.89Å; T496-N498 VanDerWaalsContact C-N 3.3Å; T496-N498 PolarHBondContact O-N 2.98Å; N498-E500 VanDerWaalsContact C-N 3.34Å; N498-E500 PolarHBondContact O-N 2.88Å; N498-Q501 HydrophobicContact CB-CB 4.3Å; N498-Q501 PolarHBondContact O-N 3.36Å; N498-Q501 WeakPolarHBondContact OD1-CB 3.32Å; N498-Q501 PolarHBondContact OD1-N 3.3Å; N498-Q501 VanDerWaalsContact OD1-N 3.13Å; N498-V502 VanDerWaalsContact O-CG2 3.32Å; N498-V502 WeakPolarHBondContact O-CG2 3.18Å; N498-V502 PolarHBondContact O-N 3.27Å; N498-V502 VanDerWaalsContact O-N 3.09Å
499M95.6Very high97.1Very high27 Ų2759.3 Ų59.313%0.13329%0.29CS..Hα-helixtrans-62.3-40.1-173.4-16668.266.200112.9P495 T496 Q501 V502 V503 I528 L532 F536 F539P495-M499 HydrophobicContact CB-CE 4.1Å; P495-M499 HydrophobicContact CB-SD 4.14Å; P495-M499 HydrophobicContact CG-CE 4.5Å; P495-M499 PolarHBondContact O-N 2.95Å; T496-M499 HydrophobicContact CG2-CE 3.86Å; M499-Q501 VanDerWaalsContact C-N 3.34Å; M499-Q501 PolarHBondContact O-N 2.95Å; M499-V502 PolarHBondContact O-N 3.41Å; M499-V503 WeakPolarHBondContact O-CG2 3.47Å; M499-V503 PolarHBondContact O-N 3.49Å; M499-I528 HydrophobicContact CE-CG2 3.79Å; M499-L532 HydrophobicContact CE-CD1 3.38Å; M499-L532 HydrophobicContact CG-CD1 4.34Å; M499-L532 HydrophobicContact SD-CD1 3.89Å; M499-F536 HydrophobicContact CG-CD2 4.23Å; M499-F536 HydrophobicContact CG-CE2 3.51Å; M499-F536 HydrophobicContact CG-CZ 3.88Å; M499-F539 HydrophobicContact CG-CE2 4.34Å; M499-F539 HydrophobicContact CG-CZ 4.37Å; M499-F539 HydrophobicContact SD-CE2 3.54Å; M499-F539 VanDerWaalsContact SD-CE2 3.54Å; M499-F539 HydrophobicContact SD-CZ 3.42Å; M499-F539 WeakPolarHBondContact SD-CZ 3.3Å
500E96.4Very high97Very high153 Ų15366 Ų6672%0.71531%0.314SS*.Hα-helixtrans-62.8-43.4-178.4-65.1-176.3173.100111.3N498 V503 A504N498-E500 VanDerWaalsContact C-N 3.34Å; N498-E500 PolarHBondContact O-N 2.88Å; E500-V503 PolarHBondContact O-N 2.77Å; E500-A504 WeakPolarHBondContact O-CB 3.25Å; E500-A504 PolarHBondContact O-N 2.92Å
501Q97.7Very high97Very high66 Ų6665.5 Ų65.531%0.30831%0.311SS..Hα-helixtrans-71.1-35.2178.5-170.364.58.900112I465 N498 M499 V503 A504 Q505I465-Q501 HydrophobicContact CB-CG 4.24Å; I465-Q501 HydrophobicContact CG2-CB 4.1Å; I465-Q501 HydrophobicContact CG2-CG 3.73Å; I465-Q501 WeakPolarHBondContact O-CG 3.33Å; I465-Q501 PolarHBondContact O-NE2 2.82Å; I465-Q501 VanDerWaalsContact O-NE2 3.13Å; N498-Q501 HydrophobicContact CB-CB 4.3Å; N498-Q501 PolarHBondContact O-N 3.36Å; N498-Q501 WeakPolarHBondContact OD1-CB 3.32Å; N498-Q501 PolarHBondContact OD1-N 3.3Å; N498-Q501 VanDerWaalsContact OD1-N 3.13Å; M499-Q501 VanDerWaalsContact C-N 3.34Å; M499-Q501 PolarHBondContact O-N 2.95Å; Q501-V503 VanDerWaalsContact C-N 3.33Å; Q501-V503 PolarHBondContact O-N 2.99Å; Q501-A504 PolarHBondContact O-N 3.48Å; Q501-Q505 HydrophobicContact CG-CG 4.43Å; Q501-Q505 WeakPolarHBondContact O-CB 3.44Å; Q501-Q505 WeakPolarHBondContact O-CG 3.24Å; Q501-Q505 PolarHBondContact O-N 3.43Å
502V97.9Very high97.1Very high0 Ų062.9 Ų62.90%030%0.299CS..Hα-helixtrans-57.2-50.6172.6171.40000110.2F461 L464 I465 N498 M499 A504 Q505 L506 F539F461-V502 HydrophobicContact CD1-CG2 4.17Å; L464-V502 HydrophobicContact CD1-CG1 4.24Å; L464-V502 HydrophobicContact CD2-CB 3.99Å; L464-V502 HydrophobicContact CD2-CG1 3.85Å; L464-V502 HydrophobicContact CD2-CG2 4.03Å; I465-V502 HydrophobicContact CD1-CG2 4.45Å; I465-V502 HydrophobicContact CG1-CG2 3.87Å; N498-V502 VanDerWaalsContact O-CG2 3.32Å; N498-V502 WeakPolarHBondContact O-CG2 3.18Å; N498-V502 PolarHBondContact O-N 3.27Å; N498-V502 VanDerWaalsContact O-N 3.09Å; M499-V502 PolarHBondContact O-N 3.41Å; V502-A504 PolarHBondContact O-N 2.94Å; V502-Q505 PolarHBondContact O-N 2.92Å; V502-L506 HydrophobicContact CG1-CD1 4.23Å; V502-L506 WeakPolarHBondContact O-CG 3.46Å; V502-L506 PolarHBondContact O-N 3.5Å; V502-F539 HydrophobicContact CG1-CE1 4.11Å; V502-F539 HydrophobicContact CG1-CZ 4.34Å
503V98Very high97.2Very high5 Ų556.9 Ų56.93%0.0327%0.273CS..Hα-helixtrans-61.3-45.2178.4169.10000111.5M499 E500 Q501 Q505 L506 R507 F536 E538 F539M499-V503 WeakPolarHBondContact O-CG2 3.47Å; M499-V503 PolarHBondContact O-N 3.49Å; E500-V503 PolarHBondContact O-N 2.77Å; Q501-V503 VanDerWaalsContact C-N 3.33Å; Q501-V503 PolarHBondContact O-N 2.99Å; V503-Q505 VanDerWaalsContact C-N 3.28Å; V503-Q505 PolarHBondContact O-N 3.27Å; V503-L506 PolarHBondContact O-N 2.94Å; V503-R507 WeakPolarHBondContact O-CB 3.41Å; V503-R507 PolarHBondContact O-N 3.25Å; V503-F536 HydrophobicContact CB-CD1 4.31Å; V503-F536 HydrophobicContact CG1-CB 4.48Å; V503-F536 HydrophobicContact CG1-CD1 4.01Å; V503-F536 HydrophobicContact CG2-CB 3.85Å; V503-F536 HydrophobicContact CG2-CD1 3.68Å; V503-F536 HydrophobicContact CG2-CD2 4.15Å; V503-F536 HydrophobicContact CG2-CE1 4.19Å; V503-F536 HydrophobicContact CG2-CG 3.63Å; V503-E538 HydrophobicContact CG1-CB 4.05Å; V503-E538 HydrophobicContact CG1-CG 3.81Å; V503-E538 WeakPolarHBondContact CG1-OE2 3.35Å; V503-F539 HydrophobicContact CG2-CE1 3.93Å; V503-F539 HydrophobicContact CG2-CE2 3.99Å; V503-F539 HydrophobicContact CG2-CZ 3.5Å; V503-F539 VanDerWaalsContact CG2-CZ 3.5Å
504A98.1Very high97.4Very high35 Ų3556.1 Ų56.129%0.28927%0.268SS..Hα-helixtrans-58.3-40.5178.500000112.2E500 Q501 V502 H508E500-A504 WeakPolarHBondContact O-CB 3.25Å; E500-A504 PolarHBondContact O-N 2.92Å; Q501-A504 PolarHBondContact O-N 3.48Å; V502-A504 PolarHBondContact O-N 2.94Å; A504-H508 WeakPolarHBondContact O-CB 3.47Å; A504-H508 PolarHBondContact O-N 3.22Å
505Q98.3Very high97.5Very high28 Ų2854.2 Ų54.213%0.13126%0.258CS..Hα-helixtrans-73.9-42.1-179.6-66.9-68.5-11.100112.2L464 F469 Q501 V502 V503 R507 H508 F509L464-Q505 HydrophobicContact CD2-CB 3.9Å; L464-Q505 WeakPolarHBondContact O-CG 3.43Å; F469-Q505 HydrophobicContact CE2-CB 4.3Å; Q501-Q505 HydrophobicContact CG-CG 4.43Å; Q501-Q505 WeakPolarHBondContact O-CB 3.44Å; Q501-Q505 WeakPolarHBondContact O-CG 3.24Å; Q501-Q505 PolarHBondContact O-N 3.43Å; V502-Q505 PolarHBondContact O-N 2.92Å; V503-Q505 VanDerWaalsContact C-N 3.28Å; V503-Q505 PolarHBondContact O-N 3.27Å; Q505-R507 VanDerWaalsContact C-N 3.25Å; Q505-R507 PolarHBondContact O-N 3.2Å; Q505-H508 PolarHBondContact O-N 3.42Å; Q505-H508 VanDerWaalsContact O-N 3.16Å; Q505-F509 WeakPolarHBondContact O-CD2 3.33Å; Q505-F509 PolarHBondContact O-N 3.26Å
506L98Very high97.5Very high5 Ų554.2 Ų54.23%0.02626%0.258CS..Hα-helixtrans-58.3-39.8173.3-67.8178.7000111.7V502 V503 K510 I511 E538 F539V502-L506 HydrophobicContact CG1-CD1 4.23Å; V502-L506 WeakPolarHBondContact O-CG 3.46Å; V502-L506 PolarHBondContact O-N 3.5Å; V503-L506 PolarHBondContact O-N 2.94Å; L506-K510 PolarHBondContact O-N 3.4Å; L506-K510 VanDerWaalsContact O-N 3.1Å; L506-I511 HydrophobicContact CD2-CB 4.02Å; L506-I511 HydrophobicContact CD2-CG1 3.88Å; L506-I511 HydrophobicContact CD2-CG2 4.25Å; L506-I511 PolarHBondContact O-N 3.14Å; L506-E538 HydrophobicContact CB-CB 4.24Å; L506-F539 HydrophobicContact CD1-CD1 4.01Å; L506-F539 HydrophobicContact CD1-CE1 3.8Å
507R97.5Very high97.7Very high147 Ų14750.1 Ų50.156%0.55523%0.233SC*.Hα-helixtrans-65.3-47173.3-171.4-172.7-61.1140.14.2112.1V503 Q505 F509 K510 E538V503-R507 WeakPolarHBondContact O-CB 3.41Å; V503-R507 PolarHBondContact O-N 3.25Å; Q505-R507 VanDerWaalsContact C-N 3.25Å; Q505-R507 PolarHBondContact O-N 3.2Å; R507-F509 PolarHBondContact O-N 2.99Å; R507-K510 PolarHBondContact O-N 3.11Å; R507-K510 VanDerWaalsContact O-N 3.14Å; R507-E538 HydrophobicContact CB-CG 3.94Å; R507-E538 IonicContact CZ-OE1 3.59Å; R507-E538 IonicContact NE-OE1 2.65Å; R507-E538 PolarHBondContact NE-OE1 3.2Å; R507-E538 VanDerWaalsContact NH2-CD 3.29Å; R507-E538 IonicContact NH2-OE1 3.05Å; R507-E538 PolarHBondContact NH2-OE1 3.3Å; R507-E538 IonicContact NH2-OE2 3.29Å; R507-E538 PolarHBondContact NH2-OE2 3.08Å
508H97.7Very high97.8Very high136 Ų13643.6 Ų43.663%0.6320%0.204SC*.Hα-helixtrans-59.5-45.1-177.6-178.566.3000112.1A504 Q505 K510A504-H508 WeakPolarHBondContact O-CB 3.47Å; A504-H508 PolarHBondContact O-N 3.22Å; Q505-H508 PolarHBondContact O-N 3.42Å; Q505-H508 VanDerWaalsContact O-N 3.16Å; H508-K510 VanDerWaalsContact C-N 3.3Å
509F97.3Very high97.8Very high45 Ų4540.4 Ų40.420%0.19719%0.188CC..THydrogen-bonded Turntrans-84.5-1.1178.3-73-82.2000114Y455 F469 Q505 R507 I511Y455-F509 HydrophobicContact CD1-CD1 4.49Å; Y455-F509 HydrophobicContact CE1-CD1 4.1Å; Y455-F509 HydrophobicContact CE1-CE1 4.33Å; Y455-F509 HydrophobicContact CE2-CD1 4.18Å; Y455-F509 AromaticContact CZ-CD1 3.93Å; F469-F509 HydrophobicContact CB-CD1 4.18Å; F469-F509 HydrophobicContact CB-CE1 3.71Å; F469-F509 HydrophobicContact CB-CE2 4.17Å; F469-F509 HydrophobicContact CB-CZ 3.71Å; F469-F509 HydrophobicContact CD1-CB 4.33Å; F469-F509 HydrophobicContact CD1-CD1 4.11Å; F469-F509 AromaticContact CD1-CD2 3.98Å; F469-F509 HydrophobicContact CD1-CD2 3.98Å; F469-F509 HydrophobicContact CD1-CE1 4.44Å; F469-F509 HydrophobicContact CD1-CE2 4.33Å; F469-F509 AromaticContact CD1-CG 3.87Å; F469-F509 HydrophobicContact CD1-CG 3.87Å; F469-F509 AromaticContact CD2-CD2 3.64Å; F469-F509 HydrophobicContact CD2-CD2 3.64Å; F469-F509 HydrophobicContact CD2-CE1 4.41Å; F469-F509 AromaticContact CD2-CE2 3.33Å; F469-F509 HydrophobicContact CD2-CE2 3.33Å; F469-F509 HydrophobicContact CD2-CG 4.32Å; F469-F509 AromaticContact CD2-CZ 3.77Å; F469-F509 HydrophobicContact CD2-CZ 3.77Å; F469-F509 HydrophobicContact CE1-CB 4.2Å; F469-F509 HydrophobicContact CE1-CD2 4.03Å; F469-F509 HydrophobicContact CE1-CG 4.08Å; F469-F509 AromaticContact CE2-CD2 3.69Å; F469-F509 HydrophobicContact CE2-CD2 3.69Å; F469-F509 AromaticContact CE2-CE2 3.73Å; F469-F509 HydrophobicContact CE2-CE2 3.73Å; F469-F509 HydrophobicContact CG-CD1 4.09Å; F469-F509 AromaticContact CG-CD2 3.83Å; F469-F509 HydrophobicContact CG-CD2 3.83Å; F469-F509 AromaticContact CG-CE1 3.97Å; F469-F509 HydrophobicContact CG-CE1 3.97Å; F469-F509 AromaticContact CG-CE2 3.7Å; F469-F509 HydrophobicContact CG-CE2 3.7Å; F469-F509 HydrophobicContact CG-CG 4.03Å; F469-F509 AromaticContact CG-CZ 3.78Å; F469-F509 HydrophobicContact CG-CZ 3.78Å; F469-F509 AromaticContact CZ-CD2 3.89Å; F469-F509 HydrophobicContact CZ-CD2 3.89Å; F469-F509 HydrophobicContact CZ-CE2 4.39Å; F469-F509 HydrophobicContact CZ-CG 4.4Å; Q505-F509 WeakPolarHBondContact O-CD2 3.33Å; Q505-F509 PolarHBondContact O-N 3.26Å; R507-F509 PolarHBondContact O-N 2.99Å; F509-I511 HydrophobicContact CB-CD1 3.8Å; F509-I511 HydrophobicContact CB-CG1 4.07Å; F509-I511 PolarHBondContact O-N 3.38Å
510K96.6Very high97.9Very high158 Ų15839.3 Ų39.369%0.68718%0.182SC*.THydrogen-bonded Turntrans52.752.9179.9-56.3-177.9-179.4-176.90112.5T423 L506 R507 H508 D512T423-K510 WeakPolarHBondContact CB-O 3.48Å; L506-K510 PolarHBondContact O-N 3.4Å; L506-K510 VanDerWaalsContact O-N 3.1Å; R507-K510 PolarHBondContact O-N 3.11Å; R507-K510 VanDerWaalsContact O-N 3.14Å; H508-K510 VanDerWaalsContact C-N 3.3Å; K510-D512 PolarHBondContact O-N 3.07Å
511I98.2Very high98Very high10 Ų1033.2 Ų33.25%0.05115%0.154CC..  trans-75.2119.9-177.9-56.7-52.5000110.3T423 A425 Y455 F469 L506 F509 G513 I541T423-I511 HydrophobicContact CG2-CD1 3.96Å; A425-I511 HydrophobicContact CB-CD1 3.94Å; A425-I511 HydrophobicContact CB-CG1 4.22Å; A425-I511 HydrophobicContact CB-CG2 3.89Å; Y455-I511 HydrophobicContact CD2-CD1 3.98Å; F469-I511 HydrophobicContact CE1-CD1 4.18Å; F469-I511 HydrophobicContact CE1-CG1 4.34Å; L506-I511 HydrophobicContact CD2-CB 4.02Å; L506-I511 HydrophobicContact CD2-CG1 3.88Å; L506-I511 HydrophobicContact CD2-CG2 4.25Å; L506-I511 PolarHBondContact O-N 3.14Å; F509-I511 HydrophobicContact CB-CD1 3.8Å; F509-I511 HydrophobicContact CB-CG1 4.07Å; F509-I511 PolarHBondContact O-N 3.38Å; I511-G513 WeakPolarHBondContact CG2-O 3.49Å; I511-I541 HydrophobicContact CG2-CD1 4.06Å
512D98.1Very high98Very high30 Ų3030 Ų3016%0.1614%0.139CC..SBendtrans-92.6-11.4179-63.5-50.2000113F422 T423 F424 K510 P542 V722F422-D512 WeakPolarHBondContact CA-OD2 3.42Å; F422-D512 HydrophobicContact CB-CB 4.32Å; F422-D512 HydrophobicContact CD1-CB 4.46Å; T423-D512 PolarHBondContact N-OD2 3.29Å; T423-D512 PolarHBondContact O-N 3.45Å; F424-D512 HydrophobicContact CE1-CB 4.48Å; K510-D512 PolarHBondContact O-N 3.07Å; D512-P542 WeakPolarHBondContact O-CD 3.42Å; D512-V722 HydrophobicContact CB-CB 4.11Å; D512-V722 HydrophobicContact CB-CG2 3.85Å
513G98.4Very high98Very high0 Ų030 Ų300%014%0.139CC..EExtended strand (participates in β ladder)trans-170.9149.5178.900000112.6F424 A425 I511 P542F424-G513 WeakPolarHBondContact CA-O 3.34Å; A425-G513 PolarHBondContact N-O 3.15Å; I511-G513 WeakPolarHBondContact CG2-O 3.49Å; G513-P542 CarbonylContact C-O 3.56Å; G513-P542 VanDerWaalsContact CA-O 3.25Å; G513-P542 WeakPolarHBondContact CA-O 3.47Å
514L98.6Very high98Very high1 Ų132.3 Ų32.31%0.00515%0.149CC..EExtended strand (participates in β ladder)trans-125.5131.5-173.1-173.465.7000111.9A425 M427 I457 L516 M529 I541 P542 M543 V544A425-L514 HydrophobicContact CB-CD1 3.79Å; M427-L514 HydrophobicContact CE-CD1 4.43Å; M427-L514 HydrophobicContact CE-CD2 4.27Å; I457-L514 HydrophobicContact CD1-CD1 4.28Å; L514-L516 HydrophobicContact CD2-CD1 4.42Å; L514-L516 HydrophobicContact CD2-CD2 4.06Å; L514-L516 HydrophobicContact CD2-CG 4.23Å; L514-L516 HydrophobicContact CG-CD2 4.26Å; L514-L516 HydrophobicContact CG-CG 4.22Å; L514-M529 HydrophobicContact CD2-CE 3.64Å; L514-M529 HydrophobicContact CD2-SD 4.12Å; L514-I541 HydrophobicContact CB-CD1 4.5Å; L514-P542 PolarHBondContact N-O 3.47Å; L514-M543 HydrophobicContact CB-CG 4.14Å; L514-M543 VanDerWaalsContact O-CA 3.32Å; L514-M543 WeakPolarHBondContact O-CA 2.81Å; L514-V544 PolarHBondContact O-N 2.88Å
515F98.8Very high98Very high0 Ų030.6 Ų30.60%014%0.135CC..EExtended strand (participates in β ladder)trans-113.1116.9174.3-173.3-136.7000111A425 V426 M427 F443 I517 V544 L546 A701 A704 L708A425-F515 PolarHBondContact O-N 2.77Å; V426-F515 WeakPolarHBondContact CA-O 3.42Å; V426-F515 HydrophobicContact CB-CB 4.34Å; V426-F515 HydrophobicContact CB-CD1 4.33Å; V426-F515 HydrophobicContact CG2-CB 4.33Å; V426-F515 HydrophobicContact CG2-CD1 3.61Å; V426-F515 HydrophobicContact CG2-CE1 4.41Å; V426-F515 HydrophobicContact CG2-CG 4.37Å; M427-F515 PolarHBondContact N-O 2.88Å; F443-F515 HydrophobicContact CB-CD1 3.73Å; F443-F515 HydrophobicContact CB-CE1 3.64Å; F443-F515 HydrophobicContact CD1-CB 4.44Å; F443-F515 AromaticContact CD1-CD1 3.77Å; F443-F515 HydrophobicContact CD1-CD1 3.77Å; F443-F515 HydrophobicContact CD1-CG 4.5Å; F443-F515 HydrophobicContact CD2-CB 4.29Å; F443-F515 AromaticContact CD2-CD1 3.48Å; F443-F515 HydrophobicContact CD2-CD1 3.48Å; F443-F515 VanDerWaalsContact CD2-CD1 3.48Å; F443-F515 AromaticContact CD2-CE1 3.91Å; F443-F515 HydrophobicContact CD2-CE1 3.91Å; F443-F515 AromaticContact CD2-CG 3.92Å; F443-F515 HydrophobicContact CD2-CG 3.92Å; F443-F515 HydrophobicContact CE1-CB 4.08Å; F443-F515 HydrophobicContact CE1-CD1 4.25Å; F443-F515 HydrophobicContact CE2-CB 3.94Å; F443-F515 HydrophobicContact CE2-CD1 4.03Å; F443-F515 HydrophobicContact CE2-CG 4.04Å; F443-F515 AromaticContact CG-CD1 3.34Å; F443-F515 HydrophobicContact CG-CD1 3.34Å; F443-F515 AromaticContact CG-CE1 3.77Å; F443-F515 HydrophobicContact CG-CE1 3.77Å; F443-F515 HydrophobicContact CG-CG 4.17Å; F443-F515 HydrophobicContact CZ-CB 3.82Å; F443-F515 HydrophobicContact CZ-CD1 4.37Å; F443-F515 HydrophobicContact CZ-CG 4.35Å; F515-I517 HydrophobicContact CD1-CD1 4.01Å; F515-I517 HydrophobicContact CD1-CG1 3.98Å; F515-I517 HydrophobicContact CE1-CD1 3.57Å; F515-I517 HydrophobicContact CE1-CG1 3.5Å; F515-I517 VanDerWaalsContact CE1-CG1 3.5Å; F515-I517 HydrophobicContact CE2-CG1 4.38Å; F515-I517 HydrophobicContact CZ-CD1 4.25Å; F515-I517 HydrophobicContact CZ-CG1 3.72Å; F515-V544 WeakPolarHBondContact CA-O 3.41Å; F515-V544 HydrophobicContact CD2-CB 4.06Å; F515-V544 HydrophobicContact CD2-CG1 4.15Å; F515-V544 WeakPolarHBondContact CD2-O 3.47Å; F515-V544 HydrophobicContact CE2-CG1 4.09Å; F515-L546 HydrophobicContact CE2-CB 3.65Å; F515-L546 HydrophobicContact CZ-CB 3.68Å; F515-L546 HydrophobicContact CZ-CD2 3.75Å; F515-L546 HydrophobicContact CZ-CG 4.34Å; F515-A701 HydrophobicContact CE1-CB 4.19Å; F515-A701 HydrophobicContact CZ-CB 4.18Å; F515-A704 HydrophobicContact CD2-CB 3.95Å; F515-A704 HydrophobicContact CE2-CB 3.35Å; F515-A704 HydrophobicContact CZ-CB 3.69Å; F515-L708 HydrophobicContact CB-CD1 3.91Å
516L98.8Very high98Very high0 Ų029.3 Ų29.30%013%0.129CC..EExtended strand (participates in β ladder)trans-108.2119.9-177.8-62.6163.7000109.1M427 V429 F461 L514 A522 C526 M529 V544 T545 L546M427-L516 HydrophobicContact CE-CD2 3.14Å; M427-L516 HydrophobicContact CG-CD2 3.81Å; M427-L516 HydrophobicContact SD-CD2 4.3Å; V429-L516 HydrophobicContact CG2-CD2 4.1Å; F461-L516 HydrophobicContact CZ-CD2 4.38Å; L514-L516 HydrophobicContact CD2-CD1 4.42Å; L514-L516 HydrophobicContact CD2-CD2 4.06Å; L514-L516 HydrophobicContact CD2-CG 4.23Å; L514-L516 HydrophobicContact CG-CD2 4.26Å; L514-L516 HydrophobicContact CG-CG 4.22Å; L516-A522 HydrophobicContact CB-CB 4.4Å; L516-C526 HydrophobicContact CD1-CB 3.63Å; L516-M529 HydrophobicContact CD1-CE 3.9Å; L516-V544 PolarHBondContact N-O 2.95Å; L516-T545 HydrophobicContact CB-CG2 4.38Å; L516-T545 CarbonylContact O-C 3.6Å; L516-T545 VanDerWaalsContact O-CA 3.28Å; L516-T545 WeakPolarHBondContact O-CA 3.33Å; L516-L546 PolarHBondContact O-N 3.12Å
517I98.8Very high98Very high0 Ų029.2 Ų29.20%013%0.129CC..EExtended strand (participates in β ladder)trans-110.3123.3176.5-56.5158.7000108.1V426 M427 N428 V429 M436 A439 V440 F515 L546 C548V426-I517 HydrophobicContact CG2-CD1 3.81Å; M427-I517 PolarHBondContact O-N 3.4Å; N428-I517 CarbonylContact C-O 3.37Å; N428-I517 WeakPolarHBondContact CA-O 3.41Å; N428-I517 WeakPolarHBondContact OD1-CB 3.32Å; N428-I517 WeakPolarHBondContact OD1-CD1 3.1Å; V429-I517 PolarHBondContact N-O 2.84Å; M436-I517 HydrophobicContact CG-CG2 4.23Å; A439-I517 HydrophobicContact CB-CD1 3.78Å; A439-I517 HydrophobicContact CB-CG1 4.31Å; A439-I517 HydrophobicContact CB-CG2 4.23Å; V440-I517 HydrophobicContact CB-CD1 4.44Å; V440-I517 HydrophobicContact CG2-CD1 3.53Å; F515-I517 HydrophobicContact CD1-CD1 4.01Å; F515-I517 HydrophobicContact CD1-CG1 3.98Å; F515-I517 HydrophobicContact CE1-CD1 3.57Å; F515-I517 HydrophobicContact CE1-CG1 3.5Å; F515-I517 VanDerWaalsContact CE1-CG1 3.5Å; F515-I517 HydrophobicContact CE2-CG1 4.38Å; F515-I517 HydrophobicContact CZ-CD1 4.25Å; F515-I517 HydrophobicContact CZ-CG1 3.72Å; I517-L546 HydrophobicContact CG1-CB 4.37Å; I517-C548 HydrophobicContact CG2-CB 3.71Å
518G98.3Very high98Very high0 Ų023 Ų230%011%0.106CC..EExtended strand (participates in β ladder)trans156.4-155.8174.600000117.8V429 L546 C548 I554V429-G518 VanDerWaalsContact O-CA 3.23Å; V429-G518 WeakPolarHBondContact O-CA 3.27Å; G518-L546 PolarHBondContact N-O 3.18Å; G518-C548 CarbonylContact C-O 3.49Å; G518-C548 VanDerWaalsContact CA-O 3.3Å; G518-C548 WeakPolarHBondContact CA-O 3.36Å; G518-C548 PolarHBondContact O-N 3.42Å; G518-I554 WeakPolarHBondContact O-CD1 3.49Å
519G96.9Very high98Very high3 Ų316.5 Ų16.53%0.0318%0.076CC..SBendtrans-77.5-159.1-169.400000114.7V429 E521 A522 F523 C548 I554V429-G519 PolarHBondContact O-N 2.99Å; V429-G519 VanDerWaalsContact O-N 3.09Å; G519-E521 PolarHBondContact O-N 3.41Å; G519-A522 WeakPolarHBondContact O-CB 3.32Å; G519-A522 PolarHBondContact O-N 3.03Å; G519-A522 VanDerWaalsContact O-N 3.09Å; G519-F523 PolarHBondContact O-N 3.28Å; G519-C548 PolarHBondContact N-O 3.18Å; G519-I554 VanDerWaalsContact C-CD1 3.47Å
520F97.4Very high98.1Very high3 Ų315 Ų151%0.0137%0.071CC..Hα-helixtrans-57.9-33.7169.9-163.2-83.9000111.4A522 F523 H524 A752 F754 R757F520-A522 VanDerWaalsContact C-N 3.33Å; F520-A522 PolarHBondContact O-N 3.48Å; F520-F523 HydrophobicContact CE2-CD1 4.42Å; F520-F523 HydrophobicContact CZ-CD1 4.43Å; F520-F523 HydrophobicContact CZ-CE1 4.41Å; F520-F523 PolarHBondContact O-N 3.09Å; F520-H524 HydrophobicContact CD1-CB 4.39Å; F520-H524 HydrophobicContact CE1-CB 4.46Å; F520-H524 VanDerWaalsContact O-CB 3.27Å; F520-H524 WeakPolarHBondContact O-CB 3.35Å; F520-H524 PolarHBondContact O-N 3.13Å; F520-A752 HydrophobicContact CE2-CB 4.29Å; F520-A752 HydrophobicContact CZ-CB 4.12Å; F520-F754 AromaticContact CE1-CD1 3.71Å; F520-F754 HydrophobicContact CE1-CD1 3.71Å; F520-F754 HydrophobicContact CE1-CE1 4.19Å; F520-F754 HydrophobicContact CE1-CG 4.39Å; F520-F754 AromaticContact CZ-CD1 3.89Å; F520-F754 HydrophobicContact CZ-CD1 3.89Å; F520-F754 HydrophobicContact CZ-CE1 4.23Å; F520-F754 HydrophobicContact CZ-CG 4.27Å; F520-R757 HydrophobicContact CB-CB 4.14Å; F520-R757 HydrophobicContact CD1-CB 3.84Å; F520-R757 HydrophobicContact CD1-CG 3.63Å; F520-R757 HydrophobicContact CD2-CB 3.86Å; F520-R757 HydrophobicContact CE1-CB 4.17Å; F520-R757 HydrophobicContact CE1-CG 3.9Å; F520-R757 HydrophobicContact CE2-CB 4.19Å; F520-R757 HydrophobicContact CG-CB 3.67Å; F520-R757 HydrophobicContact CG-CG 3.99Å; F520-R757 HydrophobicContact CZ-CB 4.34Å; F520-R757 HydrophobicContact CZ-CG 4.48Å
521E97.6Very high98.1Very high25 Ų2511.7 Ų11.712%0.1176%0.058CC..Hα-helixtrans-63.8-34.3175.8-67.874.6-164.900112.8V429 K492 L494 G519 S525 R757V429-E521 HydrophobicContact CG1-CB 3.96Å; K492-E521 HydrophobicContact CB-CG 4.25Å; L494-E521 HydrophobicContact CD2-CB 4.17Å; L494-E521 HydrophobicContact CD2-CG 4.44Å; G519-E521 PolarHBondContact O-N 3.41Å; E521-S525 VanDerWaalsContact O-CB 3.24Å; E521-S525 WeakPolarHBondContact O-CB 3.38Å; E521-S525 PolarHBondContact O-N 2.85Å; E521-S525 PolarHBondContact O-OG 3.4Å; E521-R757 IonicContact OE1-CZ 3.28Å; E521-R757 IonicContact OE1-NH1 3.13Å; E521-R757 PolarHBondContact OE1-NH1 3.21Å
522A98.1Very high98Very high0 Ų013.7 Ų13.70%07%0.068CC..Hα-helixtrans-67.1-48.6175.800000110.9V429 L516 G519 F520 S525 C526 T545V429-A522 HydrophobicContact CB-CB 3.96Å; L516-A522 HydrophobicContact CB-CB 4.4Å; G519-A522 WeakPolarHBondContact O-CB 3.32Å; G519-A522 PolarHBondContact O-N 3.03Å; G519-A522 VanDerWaalsContact O-N 3.09Å; F520-A522 VanDerWaalsContact C-N 3.33Å; F520-A522 PolarHBondContact O-N 3.48Å; A522-S525 PolarHBondContact O-N 2.54Å; A522-C526 PolarHBondContact O-N 3.42Å; A522-T545 HydrophobicContact CB-CG2 3.96Å
523F98.1Very high98Very high0 Ų013 Ų130%06%0.063CC..Hα-helixtrans-57-51.1174.3161.3-111000111.6G519 F520 S525 C526 L527 I554 P555 L732 V745 L748 A752 F754G519-F523 PolarHBondContact O-N 3.28Å; F520-F523 HydrophobicContact CE2-CD1 4.42Å; F520-F523 HydrophobicContact CZ-CD1 4.43Å; F520-F523 HydrophobicContact CZ-CE1 4.41Å; F520-F523 PolarHBondContact O-N 3.09Å; F523-S525 VanDerWaalsContact C-N 3.3Å; F523-S525 PolarHBondContact O-N 3.45Å; F523-C526 WeakPolarHBondContact O-CB 3.33Å; F523-C526 PolarHBondContact O-N 3.38Å; F523-L527 HydrophobicContact CZ-CD2 4.45Å; F523-L527 PolarHBondContact O-N 3.12Å; F523-I554 HydrophobicContact CB-CG2 4.11Å; F523-I554 HydrophobicContact CG-CG2 4.48Å; F523-P555 HydrophobicContact CD1-CG 4.14Å; F523-P555 HydrophobicContact CE1-CG 3.78Å; F523-P555 HydrophobicContact CE2-CG 4.33Å; F523-P555 HydrophobicContact CZ-CG 3.89Å; F523-L732 HydrophobicContact CB-CD1 4.24Å; F523-L732 HydrophobicContact CD2-CD1 3.96Å; F523-L732 HydrophobicContact CG-CD1 4.36Å; F523-V745 HydrophobicContact CD2-CB 4.36Å; F523-V745 HydrophobicContact CD2-CG1 4.14Å; F523-V745 HydrophobicContact CE2-CB 4Å; F523-V745 HydrophobicContact CE2-CG1 4.24Å; F523-L748 HydrophobicContact CE2-CB 3.74Å; F523-L748 HydrophobicContact CE2-CD1 4.35Å; F523-L748 HydrophobicContact CZ-CB 3.98Å; F523-A752 HydrophobicContact CE1-CB 3.93Å; F523-A752 HydrophobicContact CZ-CB 4.37Å; F523-F754 HydrophobicContact CE1-CE1 4.09Å; F523-F754 HydrophobicContact CE1-CZ 4.1Å; F523-F754 HydrophobicContact CZ-CZ 4.47Å
524H98Very high97.8Very high52 Ų5222.5 Ų22.524%0.24111%0.108CC..Hα-helixtrans-62.8-38.3-179.4-172-169.1000111.6F520 L527 I528 F754F520-H524 HydrophobicContact CD1-CB 4.39Å; F520-H524 HydrophobicContact CE1-CB 4.46Å; F520-H524 VanDerWaalsContact O-CB 3.27Å; F520-H524 WeakPolarHBondContact O-CB 3.35Å; F520-H524 PolarHBondContact O-N 3.13Å; H524-L527 PolarHBondContact O-N 2.64Å; H524-I528 WeakPolarHBondContact O-CD1 3.42Å; H524-I528 VanDerWaalsContact O-CG1 3.27Å; H524-I528 WeakPolarHBondContact O-CG1 3.32Å; H524-I528 PolarHBondContact O-N 2.74Å; H524-F754 AromaticContact CD2-CE1 3.8Å
525S98.3Very high97.7Very high0 Ų029.8 Ų29.80%014%0.14CC..Hα-helixtrans-63.2-43.5175.8-61.30000112.3F461 L494 P495 E521 A522 F523 L527 I528 M529F461-S525 VanDerWaalsContact CE2-CB 3.48Å; F461-S525 VanDerWaalsContact CE2-OG 3.22Å; F461-S525 WeakPolarHBondContact CE2-OG 3.45Å; L494-S525 WeakPolarHBondContact CD2-OG 3.33Å; P495-S525 VanDerWaalsContact CD-OG 3.27Å; P495-S525 WeakPolarHBondContact CD-OG 3.04Å; E521-S525 VanDerWaalsContact O-CB 3.24Å; E521-S525 WeakPolarHBondContact O-CB 3.38Å; E521-S525 PolarHBondContact O-N 2.85Å; E521-S525 PolarHBondContact O-OG 3.4Å; A522-S525 PolarHBondContact O-N 2.54Å; F523-S525 VanDerWaalsContact C-N 3.3Å; F523-S525 PolarHBondContact O-N 3.45Å; S525-L527 VanDerWaalsContact C-N 3.33Å; S525-I528 PolarHBondContact O-N 3.49Å; S525-M529 WeakPolarHBondContact O-CE 3.49Å; S525-M529 WeakPolarHBondContact O-CG 3.22Å; S525-M529 PolarHBondContact O-N 3.19Å; S525-M529 VanDerWaalsContact O-N 3.08Å
526C98.3Very high97.6Very high0 Ų031.2 Ų31.20%015%0.146CC..Hα-helixtrans-60.1-44.4174.8-168.30000111.4L516 A522 F523 M529 T530 T545 V745L516-C526 HydrophobicContact CD1-CB 3.63Å; A522-C526 PolarHBondContact O-N 3.42Å; F523-C526 WeakPolarHBondContact O-CB 3.33Å; F523-C526 PolarHBondContact O-N 3.38Å; C526-M529 PolarHBondContact O-N 2.57Å; C526-T530 WeakPolarHBondContact O-CB 3.14Å; C526-T530 PolarHBondContact O-N 3.34Å; C526-T530 PolarHBondContact O-OG1 2.83Å; C526-T545 VanDerWaalsContact CB-OG1 3.27Å; C526-T545 WeakPolarHBondContact CB-OG1 3.47Å; C526-V745 HydrophobicContact CB-CG1 4.13Å
527L98.2Very high97.5Very high3 Ų337.4 Ų37.42%0.01617%0.169CC..Hα-helixtrans-60.1-50177179.262.8000111.7F523 H524 S525 M529 T530 E531 V745 M746 K749 F754F523-L527 HydrophobicContact CZ-CD2 4.45Å; F523-L527 PolarHBondContact O-N 3.12Å; H524-L527 PolarHBondContact O-N 2.64Å; S525-L527 VanDerWaalsContact C-N 3.33Å; L527-M529 VanDerWaalsContact C-N 3.34Å; L527-M529 PolarHBondContact O-N 2.94Å; L527-T530 WeakPolarHBondContact O-CB 3.39Å; L527-T530 PolarHBondContact O-N 3.36Å; L527-T530 VanDerWaalsContact O-N 3.08Å; L527-E531 HydrophobicContact CD1-CG 4.28Å; L527-E531 WeakPolarHBondContact O-CG 3.48Å; L527-E531 PolarHBondContact O-N 3.25Å; L527-V745 HydrophobicContact CB-CB 4.49Å; L527-V745 HydrophobicContact CB-CG2 4.44Å; L527-V745 HydrophobicContact CD1-CG2 4.26Å; L527-M746 HydrophobicContact CD1-SD 3.52Å; L527-M746 VanDerWaalsContact CD1-SD 3.52Å; L527-K749 HydrophobicContact CD1-CB 4.32Å; L527-K749 HydrophobicContact CD1-CD 4.33Å; L527-K749 HydrophobicContact CD2-CB 4.07Å; L527-K749 HydrophobicContact CD2-CD 4.12Å; L527-K749 HydrophobicContact CD2-CG 3.89Å; L527-F754 HydrophobicContact CD2-CE1 3.81Å; L527-F754 HydrophobicContact CD2-CZ 3.47Å; L527-F754 VanDerWaalsContact CD2-CZ 3.47Å
528I97.9Very high97.4Very high16 Ų1638.8 Ų38.88%0.08218%0.176CC..Hα-helixtrans-56.1-48.1178.3-70.9161.4000111.1L494 P495 T496 M499 H524 S525 T530 E531 L532L494-I528 HydrophobicContact CD1-CD1 4.23Å; P495-I528 HydrophobicContact CG-CB 4.31Å; P495-I528 HydrophobicContact CG-CG2 4.06Å; T496-I528 HydrophobicContact CG2-CD1 4.14Å; T496-I528 HydrophobicContact CG2-CG2 3.98Å; M499-I528 HydrophobicContact CE-CG2 3.79Å; H524-I528 WeakPolarHBondContact O-CD1 3.42Å; H524-I528 VanDerWaalsContact O-CG1 3.27Å; H524-I528 WeakPolarHBondContact O-CG1 3.32Å; H524-I528 PolarHBondContact O-N 2.74Å; S525-I528 PolarHBondContact O-N 3.49Å; I528-T530 VanDerWaalsContact C-N 3.28Å; I528-T530 PolarHBondContact O-N 3.17Å; I528-E531 PolarHBondContact O-N 3.27Å; I528-L532 HydrophobicContact CG2-CD1 3.92Å; I528-L532 WeakPolarHBondContact O-CB 3.38Å; I528-L532 WeakPolarHBondContact O-CG 3.41Å; I528-L532 PolarHBondContact O-N 2.66Å; I528-L532 VanDerWaalsContact O-N 3.15Å
529M98.1Very high97.4Very high1 Ų138.9 Ų38.91%0.00518%0.176CC..Hα-helixtrans-63.5-37179.2-69.9-176.4-66.900111.5F461 P495 L514 L516 S525 C526 L527 L532 R533 F539 M543F461-M529 HydrophobicContact CE1-SD 4.3Å; F461-M529 HydrophobicContact CZ-CE 4.21Å; P495-M529 HydrophobicContact CB-CG 4.4Å; P495-M529 HydrophobicContact CG-CG 4.2Å; L514-M529 HydrophobicContact CD2-CE 3.64Å; L514-M529 HydrophobicContact CD2-SD 4.12Å; L516-M529 HydrophobicContact CD1-CE 3.9Å; S525-M529 WeakPolarHBondContact O-CE 3.49Å; S525-M529 WeakPolarHBondContact O-CG 3.22Å; S525-M529 PolarHBondContact O-N 3.19Å; S525-M529 VanDerWaalsContact O-N 3.08Å; C526-M529 PolarHBondContact O-N 2.57Å; L527-M529 VanDerWaalsContact C-N 3.34Å; L527-M529 PolarHBondContact O-N 2.94Å; M529-L532 PolarHBondContact O-N 2.98Å; M529-R533 PolarHBondContact O-N 2.64Å; M529-F539 HydrophobicContact CB-CB 4.33Å; M529-F539 HydrophobicContact CB-CD1 3.97Å; M529-F539 HydrophobicContact CB-CD2 4.11Å; M529-F539 HydrophobicContact CB-CE1 4.29Å; M529-F539 HydrophobicContact CB-CE2 4.42Å; M529-F539 HydrophobicContact CB-CG 3.89Å; M529-F539 HydrophobicContact CG-CD1 3.92Å; M529-F539 HydrophobicContact CG-CD2 4.36Å; M529-F539 HydrophobicContact CG-CE1 3.74Å; M529-F539 HydrophobicContact CG-CE2 4.2Å; M529-F539 HydrophobicContact CG-CG 4.25Å; M529-F539 HydrophobicContact CG-CZ 3.9Å; M529-F539 WeakPolarHBondContact O-CB 3.21Å; M529-F539 WeakPolarHBondContact O-CD2 3.34Å; M529-F539 HydrophobicContact SD-CD1 4.04Å; M529-F539 HydrophobicContact SD-CE1 3.8Å; M529-F539 HydrophobicContact SD-CZ 4.45Å; M529-M543 HydrophobicContact CB-CE 4.08Å; M529-M543 HydrophobicContact CB-SD 3.93Å; M529-M543 HydrophobicContact CE-SD 3.87Å; M529-M543 HydrophobicContact SD-SD 4.38Å
530T97.8Very high97.4Very high14 Ų1438.7 Ų38.79%0.08618%0.175CC..Hα-helixtrans-64.9-45.6177.5-55.90000111.8C526 L527 I528 L532 R533 M543 A730 V745 M746C526-T530 WeakPolarHBondContact O-CB 3.14Å; C526-T530 PolarHBondContact O-N 3.34Å; C526-T530 PolarHBondContact O-OG1 2.83Å; L527-T530 WeakPolarHBondContact O-CB 3.39Å; L527-T530 PolarHBondContact O-N 3.36Å; L527-T530 VanDerWaalsContact O-N 3.08Å; I528-T530 VanDerWaalsContact C-N 3.28Å; I528-T530 PolarHBondContact O-N 3.17Å; T530-L532 PolarHBondContact O-N 3.27Å; T530-R533 WeakPolarHBondContact O-CB 3.19Å; T530-R533 VanDerWaalsContact O-CG 3.31Å; T530-R533 WeakPolarHBondContact O-CG 3.25Å; T530-R533 PolarHBondContact O-N 3.26Å; T530-M543 WeakPolarHBondContact OG1-CE 3.39Å; T530-A730 HydrophobicContact CG2-CB 3.87Å; T530-A730 WeakPolarHBondContact OG1-CB 3.47Å; T530-V745 HydrophobicContact CG2-CG2 4.4Å; T530-M746 HydrophobicContact CG2-CG 3.96Å; T530-M746 HydrophobicContact CG2-SD 4.08Å
531E96.8Very high97.5Very high87 Ų8739 Ų3941%0.40718%0.176SC..Hα-helixtrans-63.9-28.6177.3-69.5-178.4152.600112.4L527 I528 M746 K749L527-E531 HydrophobicContact CD1-CG 4.28Å; L527-E531 WeakPolarHBondContact O-CG 3.48Å; L527-E531 PolarHBondContact O-N 3.25Å; I528-E531 PolarHBondContact O-N 3.27Å; E531-M746 HydrophobicContact CG-CE 4.3Å; E531-M746 HydrophobicContact CG-SD 3.94Å; E531-K749 WeakPolarHBondContact OE1-CE 3.32Å; E531-K749 IonicContact OE1-NZ 2.84Å; E531-K749 PolarHBondContact OE1-NZ 3.45Å
532L96.8Very high97.5Very high52 Ų5237.9 Ų37.927%0.27217%0.171SC..G310 helixtrans-91.27.2-179.6-66175.5000114.4M499 I528 M529 T530 Q534 K535 F536 F539M499-L532 HydrophobicContact CE-CD1 3.38Å; M499-L532 HydrophobicContact CG-CD1 4.34Å; M499-L532 HydrophobicContact SD-CD1 3.89Å; I528-L532 HydrophobicContact CG2-CD1 3.92Å; I528-L532 WeakPolarHBondContact O-CB 3.38Å; I528-L532 WeakPolarHBondContact O-CG 3.41Å; I528-L532 PolarHBondContact O-N 2.66Å; I528-L532 VanDerWaalsContact O-N 3.15Å; M529-L532 PolarHBondContact O-N 2.98Å; T530-L532 PolarHBondContact O-N 3.27Å; L532-Q534 PolarHBondContact O-N 3.06Å; L532-K535 PolarHBondContact O-N 3.48Å; L532-F536 HydrophobicContact CB-CD2 4.11Å; L532-F536 HydrophobicContact CD1-CE2 4.43Å; L532-F536 PolarHBondContact O-N 3.43Å; L532-F539 HydrophobicContact CB-CD2 3.93Å; L532-F539 HydrophobicContact CB-CE2 4.09Å; L532-F539 HydrophobicContact CD1-CE2 4.47Å
533R97.1Very high97.5Very high15 Ų1537.9 Ų37.96%0.05717%0.171CC..G310 helixtrans-55.5-33.3176.9-81176.3168.5-178.9-6113.7M529 T530 K535 F539 C540 I541 A726 S729M529-R533 PolarHBondContact O-N 2.64Å; T530-R533 WeakPolarHBondContact O-CB 3.19Å; T530-R533 VanDerWaalsContact O-CG 3.31Å; T530-R533 WeakPolarHBondContact O-CG 3.25Å; T530-R533 PolarHBondContact O-N 3.26Å; R533-K535 PolarHBondContact O-N 3.48Å; R533-F539 HydrophobicContact CG-CB 4.03Å; R533-F539 WeakPolarHBondContact CG-O 3.41Å; R533-F539 PolarHBondContact NE-O 2.94Å; R533-C540 PolarHBondContact O-SG 3.48Å; R533-I541 PolarHBondContact NH2-O 3.5Å; R533-A726 PolarHBondContact NH1-O 3.41Å; R533-S729 PolarHBondContact NH1-OG 3.49Å; R533-S729 VanDerWaalsContact NH1-OG 3.09Å; R533-S729 PolarHBondContact NH2-OG 3.32Å
534Q95.1Very high97.6Very high201 Ų20138 Ų3894%0.93917%0.172SC*.G310 helixtrans-66.9-25.9176.6-65.6-173.2-4.900112.9L532L532-Q534 PolarHBondContact O-N 3.06Å
535K96.4Very high97.6Very high153 Ų15335.6 Ų35.667%0.66516%0.16SC*.THydrogen-bonded Turntrans-94.6-35.1-177.9-173.3174.2178179.70112.5L532 R533L532-K535 PolarHBondContact O-N 3.48Å; R533-K535 PolarHBondContact O-N 3.48Å
536F97Very high97.6Very high30 Ų3035.6 Ų35.613%0.13216%0.16CC..  trans-127.4115.9-174.8-56.8-69.5000111.2M499 V503 L532 E538 F539M499-F536 HydrophobicContact CG-CD2 4.23Å; M499-F536 HydrophobicContact CG-CE2 3.51Å; M499-F536 HydrophobicContact CG-CZ 3.88Å; V503-F536 HydrophobicContact CB-CD1 4.31Å; V503-F536 HydrophobicContact CG1-CB 4.48Å; V503-F536 HydrophobicContact CG1-CD1 4.01Å; V503-F536 HydrophobicContact CG2-CB 3.85Å; V503-F536 HydrophobicContact CG2-CD1 3.68Å; V503-F536 HydrophobicContact CG2-CD2 4.15Å; V503-F536 HydrophobicContact CG2-CE1 4.19Å; V503-F536 HydrophobicContact CG2-CG 3.63Å; L532-F536 HydrophobicContact CB-CD2 4.11Å; L532-F536 HydrophobicContact CD1-CE2 4.43Å; L532-F536 PolarHBondContact O-N 3.43Å; F536-E538 PolarHBondContact O-N 3.4Å; F536-F539 HydrophobicContact CB-CD2 3.76Å; F536-F539 HydrophobicContact CB-CE2 4Å; F536-F539 HydrophobicContact CB-CG 4.32Å; F536-F539 AromaticContact CD2-CD2 3.95Å; F536-F539 HydrophobicContact CD2-CD2 3.95Å; F536-F539 AromaticContact CD2-CE2 3.55Å; F536-F539 HydrophobicContact CD2-CE2 3.55Å; F536-F539 HydrophobicContact CD2-CZ 4.49Å; F536-F539 HydrophobicContact CE2-CE2 4.35Å; F536-F539 HydrophobicContact CG-CD2 4.3Å; F536-F539 HydrophobicContact CG-CE2 4.09Å; F536-F539 PolarHBondContact O-N 3.3Å
537R96Very high97.6Very high131 Ų13135.7 Ų35.749%0.49416%0.161SC..G310 helixtrans-58.7-33.3177.2177.2-179.7174.1106.2-2.3111.5F539 C540 S721 Y723R537-F539 PolarHBondContact O-N 2.94Å; R537-C540 WeakPolarHBondContact O-CA 3.15Å; R537-C540 WeakPolarHBondContact O-CB 3.42Å; R537-C540 PolarHBondContact O-N 3.24Å; R537-S721 PolarHBondContact NH2-OG 2.9Å; R537-Y723 HydrophobicContact CG-CD2 4.06Å; R537-Y723 HydrophobicContact CG-CE2 4.07Å
538E97.2Very high97.6Very high29 Ų2935.6 Ų35.614%0.13616%0.161CC..G310 helixtrans-67-16.3-176.3-66.171.2-164.800113.3V503 L506 R507 F536V503-E538 HydrophobicContact CG1-CB 4.05Å; V503-E538 HydrophobicContact CG1-CG 3.81Å; V503-E538 WeakPolarHBondContact CG1-OE2 3.35Å; L506-E538 HydrophobicContact CB-CB 4.24Å; R507-E538 HydrophobicContact CB-CG 3.94Å; R507-E538 IonicContact CZ-OE1 3.59Å; R507-E538 IonicContact NE-OE1 2.65Å; R507-E538 PolarHBondContact NE-OE1 3.2Å; R507-E538 VanDerWaalsContact NH2-CD 3.29Å; R507-E538 IonicContact NH2-OE1 3.05Å; R507-E538 PolarHBondContact NH2-OE1 3.3Å; R507-E538 IonicContact NH2-OE2 3.29Å; R507-E538 PolarHBondContact NH2-OE2 3.08Å; F536-E538 PolarHBondContact O-N 3.4Å
539F97.8Very high97.6Very high1 Ų135.5 Ų35.50%0.00416%0.161CC..G310 helixtrans-90.9-7.3170.7-59.1-29.7000113.2M499 V502 V503 L506 M529 L532 R533 F536 R537 I541M499-F539 HydrophobicContact CG-CE2 4.34Å; M499-F539 HydrophobicContact CG-CZ 4.37Å; M499-F539 HydrophobicContact SD-CE2 3.54Å; M499-F539 VanDerWaalsContact SD-CE2 3.54Å; M499-F539 HydrophobicContact SD-CZ 3.42Å; M499-F539 WeakPolarHBondContact SD-CZ 3.3Å; V502-F539 HydrophobicContact CG1-CE1 4.11Å; V502-F539 HydrophobicContact CG1-CZ 4.34Å; V503-F539 HydrophobicContact CG2-CE1 3.93Å; V503-F539 HydrophobicContact CG2-CE2 3.99Å; V503-F539 HydrophobicContact CG2-CZ 3.5Å; V503-F539 VanDerWaalsContact CG2-CZ 3.5Å; L506-F539 HydrophobicContact CD1-CD1 4.01Å; L506-F539 HydrophobicContact CD1-CE1 3.8Å; M529-F539 HydrophobicContact CB-CB 4.33Å; M529-F539 HydrophobicContact CB-CD1 3.97Å; M529-F539 HydrophobicContact CB-CD2 4.11Å; M529-F539 HydrophobicContact CB-CE1 4.29Å; M529-F539 HydrophobicContact CB-CE2 4.42Å; M529-F539 HydrophobicContact CB-CG 3.89Å; M529-F539 HydrophobicContact CG-CD1 3.92Å; M529-F539 HydrophobicContact CG-CD2 4.36Å; M529-F539 HydrophobicContact CG-CE1 3.74Å; M529-F539 HydrophobicContact CG-CE2 4.2Å; M529-F539 HydrophobicContact CG-CG 4.25Å; M529-F539 HydrophobicContact CG-CZ 3.9Å; M529-F539 WeakPolarHBondContact O-CB 3.21Å; M529-F539 WeakPolarHBondContact O-CD2 3.34Å; M529-F539 HydrophobicContact SD-CD1 4.04Å; M529-F539 HydrophobicContact SD-CE1 3.8Å; M529-F539 HydrophobicContact SD-CZ 4.45Å; L532-F539 HydrophobicContact CB-CD2 3.93Å; L532-F539 HydrophobicContact CB-CE2 4.09Å; L532-F539 HydrophobicContact CD1-CE2 4.47Å; R533-F539 HydrophobicContact CG-CB 4.03Å; R533-F539 WeakPolarHBondContact CG-O 3.41Å; R533-F539 PolarHBondContact NE-O 2.94Å; F536-F539 HydrophobicContact CB-CD2 3.76Å; F536-F539 HydrophobicContact CB-CE2 4Å; F536-F539 HydrophobicContact CB-CG 4.32Å; F536-F539 AromaticContact CD2-CD2 3.95Å; F536-F539 HydrophobicContact CD2-CD2 3.95Å; F536-F539 AromaticContact CD2-CE2 3.55Å; F536-F539 HydrophobicContact CD2-CE2 3.55Å; F536-F539 HydrophobicContact CD2-CZ 4.49Å; F536-F539 HydrophobicContact CE2-CE2 4.35Å; F536-F539 HydrophobicContact CG-CD2 4.3Å; F536-F539 HydrophobicContact CG-CE2 4.09Å; F536-F539 PolarHBondContact O-N 3.3Å; R537-F539 PolarHBondContact O-N 2.94Å; F539-I541 PolarHBondContact O-N 2.94Å
540C98.2Very high97.6Very high0 Ų035.8 Ų35.80%016%0.163CC..SBendtrans-79.646.9175.5-56.80000111R533 R537 Y723 T724 T725R533-C540 PolarHBondContact O-SG 3.48Å; R537-C540 WeakPolarHBondContact O-CA 3.15Å; R537-C540 WeakPolarHBondContact O-CB 3.42Å; R537-C540 PolarHBondContact O-N 3.24Å; C540-Y723 HydrophobicContact CB-CD2 3.5Å; C540-Y723 VanDerWaalsContact CB-CD2 3.5Å; C540-Y723 HydrophobicContact CB-CE2 3.32Å; C540-Y723 HydrophobicContact CB-CG 4.3Å; C540-Y723 CarbonylContact O-C 3.57Å; C540-Y723 VanDerWaalsContact O-CA 3.29Å; C540-Y723 WeakPolarHBondContact O-CA 3.47Å; C540-Y723 VanDerWaalsContact SG-CE2 3.58Å; C540-T724 CarbonylContact C-O 3.59Å; C540-T724 VanDerWaalsContact C-O 3.23Å; C540-T724 WeakPolarHBondContact CA-O 3.46Å; C540-T724 WeakPolarHBondContact CB-O 3.43Å; C540-T724 PolarHBondContact O-N 2.87Å; C540-T725 HydrophobicContact CB-CG2 4.47Å
541I98.1Very high97.6Very high9 Ų936 Ų365%0.04616%0.164CC..SBendtrans-124.5159176.258.5175.8000109.3I511 L514 R533 F539 M543I511-I541 HydrophobicContact CG2-CD1 4.06Å; L514-I541 HydrophobicContact CB-CD1 4.5Å; R533-I541 PolarHBondContact NH2-O 3.5Å; F539-I541 PolarHBondContact O-N 2.94Å; I541-M543 HydrophobicContact CG1-CG 4.41Å
542P98.6Very high97.6Very high1 Ų132.4 Ų32.41%0.00615%0.148CC..  trans-59.7135.2170.1-24.535.1000112.4D512 G513 L514 L708 K711 A712 V722 T724 S729D512-P542 WeakPolarHBondContact O-CD 3.42Å; G513-P542 CarbonylContact C-O 3.56Å; G513-P542 VanDerWaalsContact CA-O 3.25Å; G513-P542 WeakPolarHBondContact CA-O 3.47Å; L514-P542 PolarHBondContact N-O 3.47Å; P542-L708 HydrophobicContact CB-CD2 3.68Å; P542-L708 WeakPolarHBondContact O-CD2 3.36Å; P542-K711 HydrophobicContact CB-CB 3.84Å; P542-K711 HydrophobicContact CG-CB 3.84Å; P542-A712 HydrophobicContact CG-CB 4.41Å; P542-V722 HydrophobicContact CG-CG1 4.32Å; P542-T724 HydrophobicContact CG-CG2 4.06Å; P542-S729 CarbonylContact C-O 3.56Å; P542-S729 VanDerWaalsContact CA-O 3.24Å; P542-S729 WeakPolarHBondContact CA-O 3.48Å
543M98.8Very high97.6Very high1 Ų130.7 Ų30.71%0.00514%0.139CC..EExtended strand (participates in β ladder)trans-133.1128.9178.4-60.7-175.6-78.600109.7L514 M529 T530 I541 S729 A730 V731L514-M543 HydrophobicContact CB-CG 4.14Å; L514-M543 VanDerWaalsContact O-CA 3.32Å; L514-M543 WeakPolarHBondContact O-CA 2.81Å; M529-M543 HydrophobicContact CB-CE 4.08Å; M529-M543 HydrophobicContact CB-SD 3.93Å; M529-M543 HydrophobicContact CE-SD 3.87Å; M529-M543 HydrophobicContact SD-SD 4.38Å; T530-M543 WeakPolarHBondContact OG1-CE 3.39Å; I541-M543 HydrophobicContact CG1-CG 4.41Å; M543-S729 PolarHBondContact N-O 2.88Å; M543-A730 HydrophobicContact CB-CB 4.46Å; M543-A730 HydrophobicContact CE-CB 3.98Å; M543-A730 WeakPolarHBondContact O-CA 3.49Å; M543-V731 PolarHBondContact O-N 2.91Å
544V98.7Very high97.5Very high2 Ų230 Ų301%0.01214%0.137CC..EExtended strand (participates in β ladder)trans-120.8129175.1179.40000109.1L514 F515 L516 A704 T707 L708 V731 L733L514-V544 PolarHBondContact O-N 2.88Å; F515-V544 WeakPolarHBondContact CA-O 3.41Å; F515-V544 HydrophobicContact CD2-CB 4.06Å; F515-V544 HydrophobicContact CD2-CG1 4.15Å; F515-V544 WeakPolarHBondContact CD2-O 3.47Å; F515-V544 HydrophobicContact CE2-CG1 4.09Å; L516-V544 PolarHBondContact N-O 2.95Å; V544-A704 HydrophobicContact CG1-CB 3.82Å; V544-T707 HydrophobicContact CG2-CG2 4Å; V544-L708 HydrophobicContact CB-CD2 4.43Å; V544-L708 HydrophobicContact CB-CG 4.26Å; V544-L708 HydrophobicContact CG2-CD2 3.76Å; V544-L708 HydrophobicContact CG2-CG 3.7Å; V544-V731 CarbonylContact C-O 3.52Å; V544-V731 WeakPolarHBondContact CA-O 3.39Å; V544-V731 HydrophobicContact CB-CG2 4.45Å; V544-V731 HydrophobicContact CG1-CG2 4.43Å; V544-V731 HydrophobicContact CG2-CG2 3.84Å; V544-L733 HydrophobicContact CG1-CB 4.09Å
545T98.6Very high97.5Very high1 Ų120.5 Ų20.51%0.0069%0.092CC..EExtended strand (participates in β ladder)trans-104.2130.4171.9-55.20000110.2L516 A522 C526 V731 L732 L733L516-T545 HydrophobicContact CB-CG2 4.38Å; L516-T545 CarbonylContact O-C 3.6Å; L516-T545 VanDerWaalsContact O-CA 3.28Å; L516-T545 WeakPolarHBondContact O-CA 3.33Å; A522-T545 HydrophobicContact CB-CG2 3.96Å; C526-T545 VanDerWaalsContact CB-OG1 3.27Å; C526-T545 WeakPolarHBondContact CB-OG1 3.47Å; T545-V731 PolarHBondContact N-O 3.26Å; T545-L732 CarbonylContact O-C 3.45Å; T545-L732 WeakPolarHBondContact O-CA 3.05Å; T545-L733 PolarHBondContact O-N 3.29Å
546L98.6Very high97.3Very high0 Ų013.5 Ų13.50%06%0.063CC..EExtended strand (participates in β ladder)trans-107.9114.8173.3-178.961.3000110.4A439 F515 L516 I517 G518 C548 I561 M700 A701A439-L546 HydrophobicContact CB-CD2 3.72Å; F515-L546 HydrophobicContact CE2-CB 3.65Å; F515-L546 HydrophobicContact CZ-CB 3.68Å; F515-L546 HydrophobicContact CZ-CD2 3.75Å; F515-L546 HydrophobicContact CZ-CG 4.34Å; L516-L546 PolarHBondContact O-N 3.12Å; I517-L546 HydrophobicContact CG1-CB 4.37Å; G518-L546 PolarHBondContact N-O 3.18Å; L546-C548 PolarHBondContact O-N 3.01Å; L546-C548 VanDerWaalsContact O-N 3.15Å; L546-I561 HydrophobicContact CD1-CD1 3.76Å; L546-I561 HydrophobicContact CD2-CD1 3.59Å; L546-I561 HydrophobicContact CG-CD1 3.66Å; L546-M700 HydrophobicContact CD1-CB 3.47Å; L546-M700 VanDerWaalsContact CD1-CB 3.47Å; L546-M700 HydrophobicContact CD1-CE 3.65Å; L546-M700 HydrophobicContact CD1-CG 4.28Å; L546-M700 HydrophobicContact CD1-SD 3.9Å; L546-M700 HydrophobicContact CD2-CB 4.33Å; L546-A701 HydrophobicContact CD2-CB 4.27Å
547P98.2Very high97.2Very high3 Ų312.8 Ų12.82%0.0196%0.061CC..EExtended strand (participates in β ladder)trans-61.3112.4178.3-25.636.4000112.7I554 T557 I561 L732 L733P547-I554 HydrophobicContact CB-CD1 3.81Å; P547-T557 HydrophobicContact CB-CG2 3.7Å; P547-T557 HydrophobicContact CG-CG2 3.85Å; P547-I561 PolarHBondContact O-N 2.99Å; P547-L732 HydrophobicContact CG-CD1 3.98Å; P547-L732 HydrophobicContact CG-CD2 3.61Å; P547-L732 HydrophobicContact CG-CG 3.78Å; P547-L733 WeakPolarHBondContact CD-O 3.21Å
548C98.2Very high97Very high0 Ų08.1 Ų8.10%05%0.049CC..BIsolated β-bridgetrans-138.5101.9177.6-170.30000110.5M436 I517 G518 G519 L546 I561M436-C548 HydrophobicContact CG-CB 4.42Å; M436-C548 WeakPolarHBondContact CG-SG 3.28Å; I517-C548 HydrophobicContact CG2-CB 3.71Å; G518-C548 CarbonylContact C-O 3.49Å; G518-C548 VanDerWaalsContact CA-O 3.3Å; G518-C548 WeakPolarHBondContact CA-O 3.36Å; G518-C548 PolarHBondContact O-N 3.42Å; G519-C548 PolarHBondContact N-O 3.18Å; L546-C548 PolarHBondContact O-N 3.01Å; L546-C548 VanDerWaalsContact O-N 3.15Å; C548-I561 CarbonylContact C-O 3.54Å; C548-I561 VanDerWaalsContact CA-O 3.27Å; C548-I561 WeakPolarHBondContact CA-O 3.5Å; C548-I561 HydrophobicContact CB-CB 4.11Å; C548-I561 HydrophobicContact CB-CG2 4.46Å; C548-I561 PolarHBondContact SG-O 2.72Å
549T97.9Very high96.8Very high14 Ų148.2 Ų8.29%0.0865%0.05CC..  trans-162.6149.5-178.7175.90000109.4S551 I554 S560 I561T549-S551 VanDerWaalsContact C-N 3.29Å; T549-S551 PolarHBondContact OG1-N 3.24Å; T549-I554 HydrophobicContact CG2-CD1 3.5Å; T549-I554 HydrophobicContact CG2-CG1 3.9Å; T549-S560 WeakPolarHBondContact CG2-OG 3.34Å; T549-S560 PolarHBondContact O-OG 3.38Å; T549-I561 PolarHBondContact N-O 3.36Å
550I97.7Very high96.8Very high8 Ų88.2 Ų8.24%0.0415%0.05CC..SBendtrans-71.1-26.8173.266.1171.9000112.3A433 N552 A566 M594 L601 Q684 Q685A433-I550 HydrophobicContact CB-CG2 4.27Å; I550-N552 PolarHBondContact O-N 3Å; I550-A566 HydrophobicContact CB-CB 3.66Å; I550-A566 HydrophobicContact CG2-CB 3.8Å; I550-M594 HydrophobicContact CD1-CB 4.07Å; I550-M594 HydrophobicContact CD1-CE 4.38Å; I550-M594 HydrophobicContact CD1-SD 4.02Å; I550-L601 HydrophobicContact CB-CD1 4.38Å; I550-L601 HydrophobicContact CD1-CD1 4.39Å; I550-L601 HydrophobicContact CG1-CD1 4.29Å; I550-L601 WeakPolarHBondContact O-CD1 3.46Å; I550-L601 WeakPolarHBondContact O-CD2 3.48Å; I550-L601 WeakPolarHBondContact O-CG 3.39Å; I550-Q684 HydrophobicContact CD1-CB 4.33Å; I550-Q685 HydrophobicContact CD1-CG 4.22Å
551S97.5Very high96.8Very high18 Ų188.2 Ų8.213%0.1265%0.05CC..SBendtrans-79.8-16.9-168.7-52.20000114.1T549 N553 C598T549-S551 VanDerWaalsContact C-N 3.29Å; T549-S551 PolarHBondContact OG1-N 3.24Å; S551-N553 VanDerWaalsContact C-N 3.26Å; S551-N553 PolarHBondContact O-N 3.48Å; S551-C598 PolarHBondContact O-SG 3.01Å
552N97.1Very high96.8Very high11 Ų117.8 Ų7.86%0.0595%0.048CC..  trans48.147.5-173.7-16234.1000113.1I550 S558 I559 S560 Y600I550-N552 PolarHBondContact O-N 3Å; N552-S558 PolarHBondContact ND2-O 2.93Å; N552-I559 WeakPolarHBondContact OD1-CA 3.36Å; N552-S560 VanDerWaalsContact CA-OG 3.25Å; N552-S560 WeakPolarHBondContact CA-OG 3.23Å; N552-S560 PolarHBondContact N-OG 2.86Å; N552-S560 PolarHBondContact OD1-N 2.9Å; N552-S560 PolarHBondContact OD1-OG 3.41Å; N552-Y600 HydrophobicContact CB-CD1 3.62Å; N552-Y600 HydrophobicContact CB-CD2 4.1Å; N552-Y600 HydrophobicContact CB-CE1 3.8Å; N552-Y600 HydrophobicContact CB-CE2 4.22Å; N552-Y600 HydrophobicContact CB-CG 3.79Å; N552-Y600 WeakPolarHBondContact ND2-CD2 3.37Å; N552-Y600 WeakPolarHBondContact ND2-CE2 3.48Å
553N96.5Very high96.7Very high16 Ų167.8 Ų7.89%0.0865%0.048CC..  trans-110.418.4-171.369.9-45.3000113.5S551 C598 R757 L758 S759S551-N553 VanDerWaalsContact C-N 3.26Å; S551-N553 PolarHBondContact O-N 3.48Å; N553-C598 HydrophobicContact CB-CB 3.83Å; N553-R757 PolarHBondContact ND2-O 3.27Å; N553-L758 HydrophobicContact CB-CD2 4.39Å; N553-S759 PolarHBondContact O-N 3.48Å
554I94.7Very high96.7Very high2 Ų28.1 Ų8.11%0.015%0.05CC..  trans-104.8132.9-173.4-53169000108.6G518 G519 F523 P547 T549 L732G518-I554 WeakPolarHBondContact O-CD1 3.49Å; G519-I554 VanDerWaalsContact C-CD1 3.47Å; F523-I554 HydrophobicContact CB-CG2 4.11Å; F523-I554 HydrophobicContact CG-CG2 4.48Å; P547-I554 HydrophobicContact CB-CD1 3.81Å; T549-I554 HydrophobicContact CG2-CD1 3.5Å; T549-I554 HydrophobicContact CG2-CG1 3.9Å; I554-L732 HydrophobicContact CG2-CD1 3.64Å
555P95.1Very high96.6Very high0 Ų08.1 Ų8.10%05%0.05CC..THydrogen-bonded Turntrans-64.2158.8175.430.5-39000112F523 T557 L748 Q751 A752F523-P555 HydrophobicContact CD1-CG 4.14Å; F523-P555 HydrophobicContact CE1-CG 3.78Å; F523-P555 HydrophobicContact CE2-CG 4.33Å; F523-P555 HydrophobicContact CZ-CG 3.89Å; P555-T557 VanDerWaalsContact C-N 3.27Å; P555-T557 PolarHBondContact O-N 2.84Å; P555-L748 HydrophobicContact CB-CB 4.36Å; P555-L748 HydrophobicContact CB-CD2 4.37Å; P555-L748 HydrophobicContact CG-CB 4.27Å; P555-Q751 HydrophobicContact CB-CB 4.16Å; P555-A752 HydrophobicContact CG-CB 4.11Å
556G93.4Very high96.6Very high6 Ų68.1 Ų8.16%0.0625%0.05CC..THydrogen-bonded Turntrans79.1-0.4175.700000115.6R736G556-R736 WeakPolarHBondContact O-CG 3.42Å
557T94.7Very high96.6Very high15 Ų158.3 Ų8.39%0.0925%0.051CC..  trans-136142171-164.40000112.3P547 P555 I559 I735P547-T557 HydrophobicContact CB-CG2 3.7Å; P547-T557 HydrophobicContact CG-CG2 3.85Å; P555-T557 VanDerWaalsContact C-N 3.27Å; P555-T557 PolarHBondContact O-N 2.84Å; T557-I559 PolarHBondContact OG1-N 3.4Å; T557-I559 PolarHBondContact OG1-O 3.49Å; T557-I735 PolarHBondContact OG1-N 3.38Å
558S91.9Very high96.6Very high33 Ų339.3 Ų9.323%0.2316%0.056CC..SBendtrans-79.1-25.8170.253.10000112.5N552 I735 W763N552-S558 PolarHBondContact ND2-O 2.93Å; S558-I735 WeakPolarHBondContact CB-O 3.48Å; S558-I735 PolarHBondContact N-O 3.44Å; S558-I735 PolarHBondContact OG-O 2.92Å; S558-W763 PolarHBondContact O-NE1 3.44Å
559I93.4Very high96.6Very high32 Ų3211.2 Ų11.216%0.1647%0.065CC..  trans-141.9127.2179.6-167.7160.9000110.6N552 T557 S563 F692 L696 I735N552-I559 WeakPolarHBondContact OD1-CA 3.36Å; T557-I559 PolarHBondContact OG1-N 3.4Å; T557-I559 PolarHBondContact OG1-O 3.49Å; I559-S563 WeakPolarHBondContact CG1-OG 3.49Å; I559-F692 HydrophobicContact CD1-CE1 3.52Å; I559-F692 HydrophobicContact CD1-CZ 3.78Å; I559-F692 HydrophobicContact CG1-CE1 4.38Å; I559-L696 HydrophobicContact CG2-CD2 4.27Å; I559-I735 HydrophobicContact CG2-CB 4.36Å; I559-I735 HydrophobicContact CG2-CD1 3.51Å; I559-I735 HydrophobicContact CG2-CG1 4.43Å
560S96.6Very high96.6Very high0 Ų010.5 Ų10.50%06%0.061CC..  trans-94.5146.3170.759.20000110.7T549 N552 G562 S563T549-S560 WeakPolarHBondContact CG2-OG 3.34Å; T549-S560 PolarHBondContact O-OG 3.38Å; N552-S560 VanDerWaalsContact CA-OG 3.25Å; N552-S560 WeakPolarHBondContact CA-OG 3.23Å; N552-S560 PolarHBondContact N-OG 2.86Å; N552-S560 PolarHBondContact OD1-N 2.9Å; N552-S560 PolarHBondContact OD1-OG 3.41Å; S560-G562 PolarHBondContact O-N 2.93Å; S560-S563 WeakPolarHBondContact O-CB 3.35Å; S560-S563 PolarHBondContact O-N 3.37Å; S560-S563 PolarHBondContact O-OG 2.96Å
561I98.1Very high96.6Very high1 Ų110.2 Ų10.21%0.0056%0.059CC..BIsolated β-bridgetrans-61.5135.6172.4-66.6155.3000109.2C434 L546 P547 C548 T549 L696 A697 M700C434-I561 WeakPolarHBondContact O-CG2 3.4Å; L546-I561 HydrophobicContact CD1-CD1 3.76Å; L546-I561 HydrophobicContact CD2-CD1 3.59Å; L546-I561 HydrophobicContact CG-CD1 3.66Å; P547-I561 PolarHBondContact O-N 2.99Å; C548-I561 CarbonylContact C-O 3.54Å; C548-I561 VanDerWaalsContact CA-O 3.27Å; C548-I561 WeakPolarHBondContact CA-O 3.5Å; C548-I561 HydrophobicContact CB-CB 4.11Å; C548-I561 HydrophobicContact CB-CG2 4.46Å; C548-I561 PolarHBondContact SG-O 2.72Å; T549-I561 PolarHBondContact N-O 3.36Å; I561-L696 HydrophobicContact CG1-CB 4.43Å; I561-L696 HydrophobicContact CG1-CD2 3.77Å; I561-L696 HydrophobicContact CG1-CG 3.83Å; I561-A697 HydrophobicContact CD1-CB 3.99Å; I561-A697 HydrophobicContact CG1-CB 4.33Å; I561-A697 HydrophobicContact CG2-CB 3.9Å; I561-M700 HydrophobicContact CD1-SD 4.31Å
562G97.8Very high96.5Very high0 Ų015.4 Ų15.40%08%0.076CC..THydrogen-bonded Turntrans96.7-16.2-178.600000113.5C434 S560 A566 D693C434-G562 WeakPolarHBondContact O-CA 3.15Å; C434-G562 PolarHBondContact O-N 3.06Å; S560-G562 PolarHBondContact O-N 2.93Å; G562-A566 PolarHBondContact O-N 3.26Å; G562-A566 VanDerWaalsContact O-N 3.1Å; G562-D693 WeakPolarHBondContact CA-OD2 3.47Å; G562-D693 PolarHBondContact N-OD1 3.18Å; G562-D693 PolarHBondContact N-OD2 3.42Å
563S97.3Very high96.5Very high0 Ų016.5 Ų16.50%08%0.082CC..Hα-helixtrans-72-32.4-179.468.70000112.6I559 S560 A566 L567I559-S563 WeakPolarHBondContact CG1-OG 3.49Å; S560-S563 WeakPolarHBondContact O-CB 3.35Å; S560-S563 PolarHBondContact O-N 3.37Å; S560-S563 PolarHBondContact O-OG 2.96Å; S563-A566 PolarHBondContact O-N 2.86Å; S563-L567 WeakPolarHBondContact O-CG 3.39Å; S563-L567 PolarHBondContact O-N 3.13Å
564D97.9Very high96.4Very high8 Ų815.8 Ų15.84%0.0438%0.078CC..Hα-helixtrans-70.6-43175.417771.9000111.7A566 L567 N568 T690 F692D564-A566 VanDerWaalsContact C-N 3.28Å; D564-A566 PolarHBondContact O-N 3.28Å; D564-L567 PolarHBondContact O-N 3.39Å; D564-N568 PolarHBondContact O-N 3.37Å; D564-N568 PolarHBondContact O-ND2 2.84Å; D564-N568 PolarHBondContact OD1-ND2 3.32Å; D564-N568 PolarHBondContact OD2-ND2 3.05Å; D564-T690 WeakPolarHBondContact OD2-CB 3.47Å; D564-T690 WeakPolarHBondContact OD2-CG2 3.23Å; D564-T690 PolarHBondContact OD2-OG1 2.75Å; D564-F692 HydrophobicContact CB-CB 4.43Å; D564-F692 HydrophobicContact CB-CD1 3.71Å; D564-F692 HydrophobicContact CB-CE1 4.42Å; D564-F692 HydrophobicContact CB-CG 4.35Å
565S98.3Very high96.4Very high3 Ų316.5 Ų16.52%0.0218%0.082CC..Hα-helixtrans-55.4-44.8171.9-61.10000112C434 N568 E569 T690 D693C434-S565 VanDerWaalsContact CB-CB 3.48Å; C434-S565 VanDerWaalsContact CB-OG 3.25Å; C434-S565 WeakPolarHBondContact CB-OG 3.32Å; S565-N568 PolarHBondContact O-N 3.34Å; S565-E569 PolarHBondContact O-N 3.22Å; S565-T690 PolarHBondContact OG-N 2.93Å; S565-T690 VanDerWaalsContact OG-N 3.12Å; S565-T690 PolarHBondContact OG-OG1 3.34Å; S565-D693 WeakPolarHBondContact CB-OD2 3.37Å; S565-D693 PolarHBondContact N-OD2 2.99Å; S565-D693 PolarHBondContact OG-OD2 3Å
566A98.3Very high96.3Very high0 Ų021.7 Ų21.70%011%0.105CC..Hα-helixtrans-63.8-45.1177.700000112.7I550 G562 S563 D564 N568 E569 I570 L601 Q684I550-A566 HydrophobicContact CB-CB 3.66Å; I550-A566 HydrophobicContact CG2-CB 3.8Å; G562-A566 PolarHBondContact O-N 3.26Å; G562-A566 VanDerWaalsContact O-N 3.1Å; S563-A566 PolarHBondContact O-N 2.86Å; D564-A566 VanDerWaalsContact C-N 3.28Å; D564-A566 PolarHBondContact O-N 3.28Å; A566-N568 VanDerWaalsContact C-N 3.31Å; A566-N568 PolarHBondContact O-N 3.14Å; A566-E569 PolarHBondContact O-N 2.91Å; A566-I570 WeakPolarHBondContact O-CD1 3.46Å; A566-I570 WeakPolarHBondContact O-CG1 3.38Å; A566-I570 PolarHBondContact O-N 3.46Å; A566-L601 HydrophobicContact CB-CD1 4.49Å; A566-L601 HydrophobicContact CB-CD2 3.98Å; A566-Q684 WeakPolarHBondContact CA-O 3.44Å; A566-Q684 WeakPolarHBondContact CB-O 3.37Å
567L98.1Very high96.3Very high4 Ų422.1 Ų22.12%0.02111%0.105CC..Hα-helixtrans-60.6-40.9177.5-74.8172.3000112.3A323 S563 D564 I570 C571 Y600 L601 L604A323-L567 HydrophobicContact CB-CB 3.87Å; S563-L567 WeakPolarHBondContact O-CG 3.39Å; S563-L567 PolarHBondContact O-N 3.13Å; D564-L567 PolarHBondContact O-N 3.39Å; L567-I570 PolarHBondContact O-N 3.1Å; L567-C571 WeakPolarHBondContact O-CB 3.36Å; L567-C571 PolarHBondContact O-N 3.19Å; L567-C571 PolarHBondContact O-SG 3.01Å; L567-C571 VanDerWaalsContact O-SG 3.41Å; L567-Y600 HydrophobicContact CD1-CE1 3.96Å; L567-Y600 HydrophobicContact CG-CE1 4.41Å; L567-L601 HydrophobicContact CD2-CD2 3.81Å; L567-L601 HydrophobicContact CG-CD2 3.93Å; L567-L604 HydrophobicContact CD1-CB 4.16Å; L567-L604 HydrophobicContact CD1-CD1 3.87Å; L567-L604 HydrophobicContact CD2-CB 3.7Å
568N98.3Very high96Very high24 Ų2421.6 Ų21.613%0.12810%0.101CC..Hα-helixtrans-64.4-44.7177.1-83.4-78.6000112S322 A323 D564 S565 A566 C571 R572 T690S322-N568 WeakPolarHBondContact CA-OD1 3.47Å; S322-N568 WeakPolarHBondContact CB-OD1 3.34Å; A323-N568 PolarHBondContact N-OD1 3.47Å; D564-N568 PolarHBondContact O-N 3.37Å; D564-N568 PolarHBondContact O-ND2 2.84Å; D564-N568 PolarHBondContact OD1-ND2 3.32Å; D564-N568 PolarHBondContact OD2-ND2 3.05Å; S565-N568 PolarHBondContact O-N 3.34Å; A566-N568 VanDerWaalsContact C-N 3.31Å; A566-N568 PolarHBondContact O-N 3.14Å; N568-C571 PolarHBondContact O-N 3.48Å; N568-R572 WeakPolarHBondContact O-CB 3.37Å; N568-R572 PolarHBondContact O-N 2.8Å; N568-T690 HydrophobicContact CB-CG2 4.19Å
569E97.6Very high95.7Very high40 Ų4026.7 Ų26.719%0.18712%0.122CC..Hα-helixtrans-63.7-42.8175.1-79.2-56148.700112.4S565 A566 C571 R572 L573S565-E569 PolarHBondContact O-N 3.22Å; A566-E569 PolarHBondContact O-N 2.91Å; E569-C571 VanDerWaalsContact C-N 3.34Å; E569-C571 PolarHBondContact O-N 2.65Å; E569-R572 PolarHBondContact O-N 2.96Å; E569-R572 IonicContact OE1-NE 3.1Å; E569-R572 IonicContact OE1-NH2 2.67Å; E569-R572 IonicContact OE2-CZ 3.96Å; E569-R572 VanDerWaalsContact OE2-CZ 3.27Å; E569-R572 IonicContact OE2-NE 2.75Å; E569-R572 PolarHBondContact OE2-NE 3.08Å; E569-R572 IonicContact OE2-NH2 3.98Å; E569-R572 PolarHBondContact OE2-NH2 3.07Å; E569-L573 VanDerWaalsContact O-CG 3.29Å; E569-L573 WeakPolarHBondContact O-CG 3.3Å; E569-L573 PolarHBondContact O-N 3.46Å
570I98.1Very high95.3Very high0 Ų028.6 Ų28.60%014%0.138CC..Hα-helixtrans-59.4-47.9176.2-65.8162.5000110A566 L567 R572 L573 I574 T593 L601 M647 L680 Q684A566-I570 WeakPolarHBondContact O-CD1 3.46Å; A566-I570 WeakPolarHBondContact O-CG1 3.38Å; A566-I570 PolarHBondContact O-N 3.46Å; L567-I570 PolarHBondContact O-N 3.1Å; I570-R572 VanDerWaalsContact C-N 3.34Å; I570-R572 PolarHBondContact O-N 2.98Å; I570-L573 PolarHBondContact O-N 3.4Å; I570-I574 HydrophobicContact CG2-CD1 3.66Å; I570-I574 HydrophobicContact CG2-CG1 4.27Å; I570-I574 VanDerWaalsContact O-CG1 3.27Å; I570-I574 WeakPolarHBondContact O-CG1 3.46Å; I570-I574 PolarHBondContact O-N 3.39Å; I570-T593 HydrophobicContact CD1-CG2 4.19Å; I570-T593 HydrophobicContact CG2-CG2 4.24Å; I570-L601 HydrophobicContact CD1-CB 4.03Å; I570-L601 HydrophobicContact CD1-CD1 4.24Å; I570-L601 HydrophobicContact CD1-CD2 4.05Å; I570-L601 HydrophobicContact CD1-CG 4.34Å; I570-M647 HydrophobicContact CG2-CE 4.12Å; I570-L680 HydrophobicContact CB-CD1 4.22Å; I570-L680 HydrophobicContact CG1-CD1 3.95Å; I570-L680 HydrophobicContact CG2-CD1 3.82Å; I570-Q684 HydrophobicContact CD1-CG 4.24Å; I570-Q684 HydrophobicContact CG1-CB 4.45Å; I570-Q684 HydrophobicContact CG1-CG 3.74Å
571C97.4Very high94.6Very high2 Ų228.7 Ų28.71%0.01414%0.138CC..Hα-helixtrans-60.2-42.4177.7-79.70000112.1L567 N568 E569 L573 I574 D575 A608L567-C571 WeakPolarHBondContact O-CB 3.36Å; L567-C571 PolarHBondContact O-N 3.19Å; L567-C571 PolarHBondContact O-SG 3.01Å; L567-C571 VanDerWaalsContact O-SG 3.41Å; N568-C571 PolarHBondContact O-N 3.48Å; E569-C571 VanDerWaalsContact C-N 3.34Å; E569-C571 PolarHBondContact O-N 2.65Å; C571-L573 PolarHBondContact O-N 2.9Å; C571-I574 PolarHBondContact O-N 2.71Å; C571-D575 PolarHBondContact O-N 2.69Å; C571-A608 VanDerWaalsContact SG-CB 3.56Å
572R96.5Very high93.5Very high126 Ų12634.9 Ų34.948%0.47517%0.17SC..Hα-helixtrans-61.4-42.6176.3-170.3-179.775.6123.5-3.9112N568 E569 I570 D575 K576N568-R572 WeakPolarHBondContact O-CB 3.37Å; N568-R572 PolarHBondContact O-N 2.8Å; E569-R572 PolarHBondContact O-N 2.96Å; E569-R572 IonicContact OE1-NE 3.1Å; E569-R572 IonicContact OE1-NH2 2.67Å; E569-R572 IonicContact OE2-CZ 3.96Å; E569-R572 VanDerWaalsContact OE2-CZ 3.27Å; E569-R572 IonicContact OE2-NE 2.75Å; E569-R572 PolarHBondContact OE2-NE 3.08Å; E569-R572 IonicContact OE2-NH2 3.98Å; E569-R572 PolarHBondContact OE2-NH2 3.07Å; I570-R572 VanDerWaalsContact C-N 3.34Å; I570-R572 PolarHBondContact O-N 2.98Å; R572-D575 PolarHBondContact O-N 3.33Å; R572-K576 WeakPolarHBondContact O-CG 3.5Å; R572-K576 PolarHBondContact O-N 2.71Å
573L96.3Very high92.4Very high35 Ų3538.4 Ų38.418%0.18321%0.207CC..Hα-helixtrans-68.1-42.7177.4-68.1167.4000111.4E569 I570 C571 D575 K576 I577 L680 S683E569-L573 VanDerWaalsContact O-CG 3.29Å; E569-L573 WeakPolarHBondContact O-CG 3.3Å; E569-L573 PolarHBondContact O-N 3.46Å; I570-L573 PolarHBondContact O-N 3.4Å; C571-L573 PolarHBondContact O-N 2.9Å; L573-D575 VanDerWaalsContact C-N 3.31Å; L573-D575 PolarHBondContact O-N 2.97Å; L573-K576 WeakPolarHBondContact O-CB 3.38Å; L573-K576 PolarHBondContact O-N 2.65Å; L573-I577 WeakPolarHBondContact O-CG1 3.43Å; L573-I577 PolarHBondContact O-N 3.06Å; L573-L680 HydrophobicContact CB-CD2 4.02Å; L573-L680 HydrophobicContact CD1-CB 4.33Å; L573-L680 HydrophobicContact CD1-CD1 4.32Å; L573-L680 HydrophobicContact CD1-CD2 3.99Å; L573-L680 HydrophobicContact CD1-CG 4.44Å; L573-S683 VanDerWaalsContact CD1-OG 3.28Å; L573-S683 WeakPolarHBondContact CD1-OG 3.47Å
574I95.7Very high91.3Very high0 Ų040.3 Ų40.30%022%0.218CC..Hα-helixtrans-60.7-41.5175-68.2168000110.9I570 C571 K576 I577 K578 V591 S609 I645 M647I570-I574 HydrophobicContact CG2-CD1 3.66Å; I570-I574 HydrophobicContact CG2-CG1 4.27Å; I570-I574 VanDerWaalsContact O-CG1 3.27Å; I570-I574 WeakPolarHBondContact O-CG1 3.46Å; I570-I574 PolarHBondContact O-N 3.39Å; C571-I574 PolarHBondContact O-N 2.71Å; I574-K576 VanDerWaalsContact C-N 3.29Å; I574-K576 PolarHBondContact O-N 2.92Å; I574-I577 CarbonylContact O-C 3.55Å; I574-I577 WeakPolarHBondContact O-CA 3.4Å; I574-I577 WeakPolarHBondContact O-CB 3.45Å; I574-I577 PolarHBondContact O-N 3.34Å; I574-I577 VanDerWaalsContact O-N 3.09Å; I574-K578 HydrophobicContact CG2-CD 4.49Å; I574-K578 HydrophobicContact CG2-CG 4.29Å; I574-K578 WeakPolarHBondContact O-CG 3.15Å; I574-K578 PolarHBondContact O-N 3.01Å; I574-V591 HydrophobicContact CG1-CG1 4.45Å; I574-S609 WeakPolarHBondContact CD1-OG 3.38Å; I574-I645 HydrophobicContact CG2-CD1 3.91Å; I574-M647 HydrophobicContact CD1-CE 3.63Å; I574-M647 HydrophobicContact CD1-SD 3.52Å; I574-M647 VanDerWaalsContact CD1-SD 3.52Å; I574-M647 HydrophobicContact CG1-CE 4.38Å; I574-M647 HydrophobicContact CG1-SD 4.28Å
575D94.7Very high90.4Very high17 Ų1748.3 Ų48.39%0.09125%0.253CS..Hα-helixtrans-63.2-36.2178.8-68.6-24.3000112Q94 R326 C571 R572 L573 K578 Q579Q94-D575 WeakPolarHBondContact CB-OD1 3.25Å; Q94-D575 WeakPolarHBondContact CB-OD2 3.3Å; R326-D575 IonicContact CZ-OD2 3.82Å; R326-D575 IonicContact NH1-OD1 2.68Å; R326-D575 PolarHBondContact NH1-OD1 3.35Å; R326-D575 IonicContact NH1-OD2 3.33Å; R326-D575 PolarHBondContact NH1-OD2 3.06Å; R326-D575 IonicContact NH2-OD2 2.74Å; R326-D575 PolarHBondContact NH2-OD2 2.91Å; C571-D575 PolarHBondContact O-N 2.69Å; R572-D575 PolarHBondContact O-N 3.33Å; L573-D575 VanDerWaalsContact C-N 3.31Å; L573-D575 PolarHBondContact O-N 2.97Å; D575-K578 PolarHBondContact O-N 3.33Å; D575-K578 IonicContact OD1-NZ 2.87Å; D575-K578 PolarHBondContact OD1-NZ 3.01Å; D575-Q579 PolarHBondContact O-N 2.94Å
576K93.1Very high90Very high110 Ų11053.7 Ų53.748%0.47827%0.273SS..Hα-helixtrans-65.5-40.3171.1-67.7176.9-178.7-179.90112.2R572 L573 I574 Q579 S580R572-K576 WeakPolarHBondContact O-CG 3.5Å; R572-K576 PolarHBondContact O-N 2.71Å; L573-K576 WeakPolarHBondContact O-CB 3.38Å; L573-K576 PolarHBondContact O-N 2.65Å; I574-K576 VanDerWaalsContact C-N 3.29Å; I574-K576 PolarHBondContact O-N 2.92Å; K576-Q579 PolarHBondContact O-N 2.95Å; K576-S580 PolarHBondContact O-N 2.93Å
577I91.6Very high89.6Confident14 Ų1456.1 Ų56.17%0.07228%0.282CS..Hα-helixtrans-62.6-44.7175.2-66.8166000110.4L573 I574 Q579 S580 A581 F589 V591 N678 L680L573-I577 WeakPolarHBondContact O-CG1 3.43Å; L573-I577 PolarHBondContact O-N 3.06Å; I574-I577 CarbonylContact O-C 3.55Å; I574-I577 WeakPolarHBondContact O-CA 3.4Å; I574-I577 WeakPolarHBondContact O-CB 3.45Å; I574-I577 PolarHBondContact O-N 3.34Å; I574-I577 VanDerWaalsContact O-N 3.09Å; I577-Q579 VanDerWaalsContact C-N 3.32Å; I577-Q579 PolarHBondContact O-N 2.84Å; I577-S580 WeakPolarHBondContact O-CB 3.21Å; I577-S580 PolarHBondContact O-N 3.5Å; I577-A581 PolarHBondContact O-N 2.88Å; I577-F589 HydrophobicContact CG2-CB 4.07Å; I577-F589 HydrophobicContact CG2-CD1 3.63Å; I577-F589 HydrophobicContact CG2-CD2 3.81Å; I577-F589 HydrophobicContact CG2-CE1 3.87Å; I577-F589 HydrophobicContact CG2-CE2 4.08Å; I577-F589 HydrophobicContact CG2-CG 3.55Å; I577-F589 HydrophobicContact CG2-CZ 4.07Å; I577-V591 HydrophobicContact CD1-CG1 4.49Å; I577-V591 HydrophobicContact CD1-CG2 3.99Å; I577-N678 HydrophobicContact CD1-CB 3.82Å; I577-L680 HydrophobicContact CD1-CD2 4.49Å
578K89.3Confident89.5Confident4 Ų456 Ų562%0.01728%0.281CS..Hα-helixtrans-58.2-44.9174.6-69.6177.1-172.31560111.4I574 D575 S580 A581 I582 S609 I645I574-K578 HydrophobicContact CG2-CD 4.49Å; I574-K578 HydrophobicContact CG2-CG 4.29Å; I574-K578 WeakPolarHBondContact O-CG 3.15Å; I574-K578 PolarHBondContact O-N 3.01Å; D575-K578 PolarHBondContact O-N 3.33Å; D575-K578 IonicContact OD1-NZ 2.87Å; D575-K578 PolarHBondContact OD1-NZ 3.01Å; K578-S580 VanDerWaalsContact C-N 3.32Å; K578-S580 PolarHBondContact O-N 3.37Å; K578-A581 VanDerWaalsContact O-CB 3.25Å; K578-A581 WeakPolarHBondContact O-CB 3.32Å; K578-A581 PolarHBondContact O-N 3.02Å; K578-I582 PolarHBondContact O-N 3.33Å; K578-S609 WeakPolarHBondContact CE-O 3.21Å; K578-S609 PolarHBondContact NZ-O 3.41Å; K578-I645 HydrophobicContact CG-CD1 3.62Å
579Q86.5Confident89.3Confident141 Ų14155.3 Ų55.366%0.65928%0.277SS*.Hα-helixtrans-61.6-41.4178.4-172.2177.50.800111.5D575 K576 I577 A581 I582D575-Q579 PolarHBondContact O-N 2.94Å; K576-Q579 PolarHBondContact O-N 2.95Å; I577-Q579 VanDerWaalsContact C-N 3.32Å; I577-Q579 PolarHBondContact O-N 2.84Å; Q579-A581 PolarHBondContact O-N 3.46Å; Q579-I582 PolarHBondContact O-N 3.39Å
580S84.6Confident89.3Confident71 Ų7153.4 Ų53.450%0.49727%0.268SS..Hα-helixtrans-60.4-34173.1-176.90000112.5K576 I577 K578 I582K576-S580 PolarHBondContact O-N 2.93Å; I577-S580 WeakPolarHBondContact O-CB 3.21Å; I577-S580 PolarHBondContact O-N 3.5Å; K578-S580 VanDerWaalsContact C-N 3.32Å; K578-S580 PolarHBondContact O-N 3.37Å; S580-I582 VanDerWaalsContact C-N 3.32Å; S580-I582 PolarHBondContact O-N 3.26Å
581A80.4Confident89.3Confident2 Ų253.4 Ų53.42%0.01727%0.268CS..Hα-helixtrans-67.9-27.4179.200000113.5I577 K578 Q579 G583 T584 F589 R643I577-A581 PolarHBondContact O-N 2.88Å; K578-A581 VanDerWaalsContact O-CB 3.25Å; K578-A581 WeakPolarHBondContact O-CB 3.32Å; K578-A581 PolarHBondContact O-N 3.02Å; Q579-A581 PolarHBondContact O-N 3.46Å; A581-G583 PolarHBondContact O-N 2.9Å; A581-T584 CarbonylContact O-C 3.51Å; A581-T584 PolarHBondContact O-N 2.96Å; A581-F589 HydrophobicContact CB-CE2 3.67Å; A581-F589 HydrophobicContact CB-CZ 4.43Å; A581-R643 HydrophobicContact CB-CB 3.89Å
582I76.6Confident89.4Confident132 Ų13254.9 Ų54.968%0.67728%0.275SS*.Hα-helixtrans-58.5-36.3-176.5-63.1172.7000111.5K578 Q579 S580K578-I582 PolarHBondContact O-N 3.33Å; Q579-I582 PolarHBondContact O-N 3.39Å; S580-I582 VanDerWaalsContact C-N 3.32Å; S580-I582 PolarHBondContact O-N 3.26Å
583G74.1Confident89.5Confident74 Ų7448.9 Ų48.976%0.76325%0.252SS*.THydrogen-bonded Turntrans-80.5-12.3178.800000114.8A581A581-G583 PolarHBondContact O-N 2.9Å
584T75.2Confident89.5Confident40 Ų4048.7 Ų48.725%0.24525%0.251CS..SBendtrans-123.7104.1-174.150.70000110.6A581 R587A581-T584 CarbonylContact O-C 3.51Å; A581-T584 PolarHBondContact O-N 2.96Å; T584-R587 VanDerWaalsContact CB-CZ 3.44Å; T584-R587 VanDerWaalsContact OG1-CZ 3.25Å; T584-R587 PolarHBondContact OG1-NH1 3.45Å; T584-R587 VanDerWaalsContact OG1-NH1 3.13Å
585K78.7Confident89.5Confident175 Ų17548.8 Ų48.876%0.76125%0.251SS*.SBendtrans-63.6139.7-177.4-63.9-172.4178.7178.50111.1
586R88.2Confident89.6Confident116 Ų11648.8 Ų48.844%0.43826%0.256SS..SBendtrans56.568.8173.3-55.9-177.9-176.9168.10.2114.3M637 Q642 N672 F673 S674R586-M637 HydrophobicContact CB-SD 3.97Å; R586-M637 HydrophobicContact CG-CB 4.48Å; R586-M637 HydrophobicContact CG-SD 4.12Å; R586-Q642 WeakPolarHBondContact CA-O 3.16Å; R586-Q642 PolarHBondContact N-O 3.5Å; R586-N672 VanDerWaalsContact CD-O 3.28Å; R586-N672 WeakPolarHBondContact CD-O 3.4Å; R586-F673 HydrophobicContact CB-CB 4.28Å; R586-F673 WeakPolarHBondContact O-CA 3.28Å; R586-F673 WeakPolarHBondContact O-CB 3.16Å; R586-S674 PolarHBondContact O-N 2.99Å
587R91.9Very high89.8Confident52 Ų5246.5 Ų46.520%0.19625%0.245CC..EExtended strand (participates in β ladder)trans-124.2135.5-179.9-169166-73.3175.32.5113.7T584 F589 Q642 R643 Y644 S674T584-R587 VanDerWaalsContact CB-CZ 3.44Å; T584-R587 VanDerWaalsContact OG1-CZ 3.25Å; T584-R587 PolarHBondContact OG1-NH1 3.45Å; T584-R587 VanDerWaalsContact OG1-NH1 3.13Å; R587-F589 HydrophobicContact CB-CE2 4.14Å; R587-F589 HydrophobicContact CG-CD2 4.18Å; R587-F589 HydrophobicContact CG-CE1 4.46Å; R587-F589 HydrophobicContact CG-CE2 3.65Å; R587-F589 HydrophobicContact CG-CZ 3.85Å; R587-Q642 PolarHBondContact N-O 3.06Å; R587-R643 CarbonylContact O-C 3.48Å; R587-R643 VanDerWaalsContact O-CA 3.25Å; R587-R643 WeakPolarHBondContact O-CA 3.49Å; R587-Y644 PolarHBondContact O-N 3.28Å; R587-S674 CarbonylContact C-O 3.6Å; R587-S674 WeakPolarHBondContact CA-O 3.39Å; R587-S674 PolarHBondContact NE-OG 3.33Å
588V94.2Very high90.1Very high0 Ų046 Ų460%024%0.242CC..EExtended strand (participates in β ladder)trans-102.6133.1172.2-176.30000109I633 M637 Y644 I646 F665 F673 S674 T675 R676V588-I633 HydrophobicContact CG1-CD1 4.34Å; V588-I633 HydrophobicContact CG2-CD1 4.29Å; V588-I633 HydrophobicContact CG2-CG2 3.59Å; V588-M637 HydrophobicContact CG2-CE 4.43Å; V588-Y644 CarbonylContact C-O 3.6Å; V588-Y644 VanDerWaalsContact CA-O 3.31Å; V588-Y644 WeakPolarHBondContact CA-O 3.29Å; V588-Y644 HydrophobicContact CG1-CD1 4.44Å; V588-I646 HydrophobicContact CG1-CD1 4.24Å; V588-F665 HydrophobicContact CG1-CD2 4.35Å; V588-F673 HydrophobicContact CB-CD2 4.23Å; V588-F673 HydrophobicContact CB-CE2 4.43Å; V588-F673 HydrophobicContact CG2-CB 4.29Å; V588-F673 HydrophobicContact CG2-CD1 4.45Å; V588-F673 HydrophobicContact CG2-CD2 3.3Å; V588-F673 HydrophobicContact CG2-CE2 3.58Å; V588-F673 HydrophobicContact CG2-CG 3.78Å; V588-F673 HydrophobicContact CG2-CZ 4.25Å; V588-S674 PolarHBondContact N-O 3.24Å; V588-T675 HydrophobicContact CB-CG2 4.23Å; V588-T675 HydrophobicContact CG1-CG2 4.27Å; V588-T675 CarbonylContact O-C 3.52Å; V588-T675 WeakPolarHBondContact O-CA 3.25Å; V588-R676 PolarHBondContact O-N 3.41Å
589F95.6Very high90.4Very high11 Ų1145.8 Ų45.85%0.04824%0.241CC..EExtended strand (participates in β ladder)trans-116125.6173-69.5-83.5000110.3I577 A581 R587 V591 Y644 I645 I646 R676 N678I577-F589 HydrophobicContact CG2-CB 4.07Å; I577-F589 HydrophobicContact CG2-CD1 3.63Å; I577-F589 HydrophobicContact CG2-CD2 3.81Å; I577-F589 HydrophobicContact CG2-CE1 3.87Å; I577-F589 HydrophobicContact CG2-CE2 4.08Å; I577-F589 HydrophobicContact CG2-CG 3.55Å; I577-F589 HydrophobicContact CG2-CZ 4.07Å; A581-F589 HydrophobicContact CB-CE2 3.67Å; A581-F589 HydrophobicContact CB-CZ 4.43Å; R587-F589 HydrophobicContact CB-CE2 4.14Å; R587-F589 HydrophobicContact CG-CD2 4.18Å; R587-F589 HydrophobicContact CG-CE1 4.46Å; R587-F589 HydrophobicContact CG-CE2 3.65Å; R587-F589 HydrophobicContact CG-CZ 3.85Å; F589-V591 HydrophobicContact CB-CG2 4.36Å; F589-Y644 PolarHBondContact N-O 2.98Å; F589-I645 HydrophobicContact CB-CG1 4.4Å; F589-I645 WeakPolarHBondContact O-CA 3.37Å; F589-I646 PolarHBondContact O-N 2.91Å; F589-R676 CarbonylContact C-O 3.56Å; F589-R676 WeakPolarHBondContact CA-O 3.35Å; F589-R676 HydrophobicContact CD1-CB 3.83Å; F589-R676 HydrophobicContact CE1-CB 3.89Å; F589-R676 HydrophobicContact CE1-CG 4.46Å; F589-N678 WeakPolarHBondContact CD1-ND2 3.35Å
590I97.3Very high91Very high0 Ų039.4 Ų39.40%021%0.211CC..EExtended strand (participates in β ladder)trans-99.4114.3168.4-55.8163.2000106.7I646 R648 T658 I661 M662 T675 R676 I677 N678I590-I646 CarbonylContact C-O 3.54Å; I590-I646 WeakPolarHBondContact CA-O 3.22Å; I590-R648 HydrophobicContact CG2-CB 4.35Å; I590-T658 HydrophobicContact CG2-CG2 3.97Å; I590-I661 HydrophobicContact CD1-CB 3.91Å; I590-I661 HydrophobicContact CD1-CG2 3.5Å; I590-I661 HydrophobicContact CG1-CG2 4.37Å; I590-M662 HydrophobicContact CD1-CB 4.14Å; I590-T675 HydrophobicContact CD1-CG2 3.72Å; I590-T675 HydrophobicContact CG1-CG2 4.14Å; I590-R676 PolarHBondContact N-O 3.33Å; I590-I677 HydrophobicContact CB-CG2 4.27Å; I590-I677 HydrophobicContact CD1-CG2 4.45Å; I590-I677 CarbonylContact O-C 3.6Å; I590-I677 VanDerWaalsContact O-CA 3.31Å; I590-I677 WeakPolarHBondContact O-CA 3.22Å; I590-N678 PolarHBondContact O-N 2.91Å
591V98Very high91.6Very high0 Ų036 Ų360%019%0.188CC..EExtended strand (participates in β ladder)trans-108.7112.6-175.8-175.10000108.6I574 I577 F589 I645 I646 M647 R648 N678 L680I574-V591 HydrophobicContact CG1-CG1 4.45Å; I577-V591 HydrophobicContact CD1-CG1 4.49Å; I577-V591 HydrophobicContact CD1-CG2 3.99Å; F589-V591 HydrophobicContact CB-CG2 4.36Å; V591-I645 HydrophobicContact CG2-CG2 4.07Å; V591-I646 PolarHBondContact N-O 3.43Å; V591-M647 HydrophobicContact CB-CE 3.76Å; V591-M647 HydrophobicContact CB-SD 3.84Å; V591-M647 HydrophobicContact CG1-CE 3.64Å; V591-M647 HydrophobicContact CG1-SD 4.27Å; V591-M647 HydrophobicContact CG2-SD 4.4Å; V591-M647 CarbonylContact O-C 3.23Å; V591-M647 WeakPolarHBondContact O-CA 3.49Å; V591-R648 PolarHBondContact O-N 3.34Å; V591-N678 CarbonylContact C-O 3.57Å; V591-N678 WeakPolarHBondContact CA-O 3.29Å; V591-N678 HydrophobicContact CG2-CB 4.48Å; V591-L680 HydrophobicContact CG1-CD1 3.76Å; V591-L680 HydrophobicContact CG1-CD2 3.81Å; V591-L680 HydrophobicContact CG1-CG 3.73Å
592E98.5Very high92.5Very high32 Ų3236 Ų3615%0.1519%0.187CC..EExtended strand (participates in β ladder)trans-86.5122.6179.2-170.6-178.9106.300110.7R648 E650 T658 N678 I679 L680E592-R648 CarbonylContact C-O 3.48Å; E592-R648 VanDerWaalsContact CA-O 3.27Å; E592-R648 WeakPolarHBondContact CA-O 3.38Å; E592-R648 IonicContact OE2-CZ 3.38Å; E592-R648 IonicContact OE2-NH1 3.72Å; E592-R648 PolarHBondContact OE2-NH1 3Å; E592-E650 HydrophobicContact CG-CB 4.2Å; E592-T658 VanDerWaalsContact OE2-CB 3.3Å; E592-T658 WeakPolarHBondContact OE2-CB 3.34Å; E592-T658 PolarHBondContact OE2-OG1 2.91Å; E592-N678 PolarHBondContact N-O 3.28Å; E592-I679 HydrophobicContact CB-CG1 4.19Å; E592-I679 HydrophobicContact CB-CG2 4.47Å; E592-L680 PolarHBondContact O-N 3.41Å
593T98.4Very high93.5Very high1 Ų129.7 Ų29.71%0.00616%0.155CC..EExtended strand (participates in β ladder)trans-101.2152.8172.666.30000110.6I570 M647 R648 E650 Q684I570-T593 HydrophobicContact CD1-CG2 4.19Å; I570-T593 HydrophobicContact CG2-CG2 4.24Å; T593-M647 HydrophobicContact CG2-CE 3.41Å; T593-M647 VanDerWaalsContact CG2-CE 3.41Å; T593-R648 PolarHBondContact N-O 2.91Å; T593-E650 WeakPolarHBondContact O-CB 3.31Å; T593-E650 PolarHBondContact O-N 3.34Å; T593-Q684 VanDerWaalsContact CA-OE1 3.25Å
594M97.8Very high94.6Very high31 Ų3126.4 Ų26.415%0.15312%0.12CC..  trans-69.3176.5164.7-74.3173.187.800109.9I550 Q684I550-M594 HydrophobicContact CD1-CB 4.07Å; I550-M594 HydrophobicContact CD1-CE 4.38Å; I550-M594 HydrophobicContact CD1-SD 4.02Å; M594-Q684 VanDerWaalsContact CG-NE2 3.3Å; M594-Q684 VanDerWaalsContact N-NE2 3.1Å
595G96Very high95.6Very high1 Ų124.5 Ų24.51%0.0111%0.108CC..  trans147.7-3.8177.400000113.7Y597 C598 E650G595-Y597 PolarHBondContact O-N 3.31Å; G595-C598 VanDerWaalsContact O-CB 3.24Å; G595-C598 WeakPolarHBondContact O-CB 3.36Å; G595-C598 PolarHBondContact O-N 3.07Å; G595-E650 PolarHBondContact N-OE1 2.96Å; G595-E650 VanDerWaalsContact N-OE1 3.11Å
596G96Very high96.5Very high18 Ų1816.1 Ų16.119%0.1867%0.072CC..THydrogen-bonded Turntrans57.1-127.2-164.100000109.2C598 C649 E650 R651G596-C598 VanDerWaalsContact C-N 3.31Å; G596-C649 PolarHBondContact O-SG 3.16Å; G596-E650 WeakPolarHBondContact CA-OE1 3.35Å; G596-E650 PolarHBondContact N-OE1 3.12Å; G596-R651 VanDerWaalsContact O-CB 3.23Å; G596-R651 WeakPolarHBondContact O-CB 3.43Å; G596-R651 PolarHBondContact O-N 2.94Å
597Y96.6Very high96.9Very high62 Ų6210.8 Ų10.824%0.2435%0.052CC..THydrogen-bonded Turntrans-86.82.6173.8-66-82.1000113.4G595 F617 R651 R756G595-Y597 PolarHBondContact O-N 3.31Å; Y597-F617 HydrophobicContact CD1-CB 4.39Å; Y597-F617 HydrophobicContact CD1-CD1 4.18Å; Y597-F617 AromaticContact CD1-CD2 3.59Å; Y597-F617 HydrophobicContact CD1-CD2 3.59Å; Y597-F617 HydrophobicContact CD1-CE1 4.42Å; Y597-F617 AromaticContact CD1-CE2 3.86Å; Y597-F617 HydrophobicContact CD1-CE2 3.86Å; Y597-F617 AromaticContact CD1-CG 3.77Å; Y597-F617 HydrophobicContact CD1-CG 3.77Å; Y597-F617 HydrophobicContact CD1-CZ 4.29Å; Y597-F617 HydrophobicContact CE1-CD2 4.2Å; Y597-F617 HydrophobicContact CE1-CE2 4.21Å; Y597-F617 HydrophobicContact CG-CG 4.45Å; Y597-F617 WeakPolarHBondContact O-CB 3.08Å; Y597-R651 HydrophobicContact CD1-CB 3.55Å; Y597-R651 HydrophobicContact CD1-CG 4.38Å; Y597-R651 HydrophobicContact CD2-CB 4.46Å; Y597-R651 HydrophobicContact CE1-CB 3.65Å; Y597-R651 HydrophobicContact CE1-CG 4.24Å; Y597-R651 HydrophobicContact CE2-CG 4.39Å; Y597-R651 HydrophobicContact CG-CB 3.99Å; Y597-R756 HydrophobicContact CD2-CB 3.83Å; Y597-R756 HydrophobicContact CD2-CG 4.33Å; Y597-R756 WeakPolarHBondContact CD2-O 3.15Å; Y597-R756 HydrophobicContact CE2-CB 4.4Å; Y597-R756 HydrophobicContact CG-CB 4.11Å
598C97.4Very high97.2Very high3 Ų38.3 Ų8.32%0.024%0.042CC..  trans-92.2115.1-178.3-172.70000110.5S551 N553 G595 G596 Y600 E618 C649 L758S551-C598 PolarHBondContact O-SG 3.01Å; N553-C598 HydrophobicContact CB-CB 3.83Å; G595-C598 VanDerWaalsContact O-CB 3.24Å; G595-C598 WeakPolarHBondContact O-CB 3.36Å; G595-C598 PolarHBondContact O-N 3.07Å; G596-C598 VanDerWaalsContact C-N 3.31Å; C598-Y600 PolarHBondContact O-N 3.19Å; C598-Y600 VanDerWaalsContact SG-CB 3.55Å; C598-E618 WeakPolarHBondContact CA-OE1 3.45Å; C598-C649 PolarHBondContact O-SG 3.29Å; C598-C649 VanDerWaalsContact O-SG 3.36Å; C598-L758 HydrophobicContact CB-CD2 3.64Å
599G97.4Very high97.2Very high0 Ų08.3 Ų8.30%04%0.042CC..THydrogen-bonded Turntrans-75.45.817800000115.4L601 A602 T603 E618 W764G599-L601 PolarHBondContact O-N 3.49Å; G599-A602 PolarHBondContact O-N 3.35Å; G599-T603 VanDerWaalsContact O-CB 3.29Å; G599-T603 WeakPolarHBondContact O-CB 3.49Å; G599-T603 PolarHBondContact O-N 2.81Å; G599-T603 PolarHBondContact O-OG1 2.9Å; G599-E618 WeakPolarHBondContact CA-OE2 3.21Å; G599-E618 PolarHBondContact N-OE1 3.48Å; G599-E618 PolarHBondContact N-OE2 2.97Å; G599-E618 VanDerWaalsContact N-OE2 3.14Å; G599-W764 VanDerWaalsContact CA-CH2 3.4Å
600Y97.8Very high97.1Very high7 Ų78.3 Ų8.33%0.0275%0.046CC..Hα-helixtrans-53.8-54.9-177.2173.3-95.6000112.3N552 L567 C598 T603 L604 W763 W764N552-Y600 HydrophobicContact CB-CD1 3.62Å; N552-Y600 HydrophobicContact CB-CD2 4.1Å; N552-Y600 HydrophobicContact CB-CE1 3.8Å; N552-Y600 HydrophobicContact CB-CE2 4.22Å; N552-Y600 HydrophobicContact CB-CG 3.79Å; N552-Y600 WeakPolarHBondContact ND2-CD2 3.37Å; N552-Y600 WeakPolarHBondContact ND2-CE2 3.48Å; L567-Y600 HydrophobicContact CD1-CE1 3.96Å; L567-Y600 HydrophobicContact CG-CE1 4.41Å; C598-Y600 PolarHBondContact O-N 3.19Å; C598-Y600 VanDerWaalsContact SG-CB 3.55Å; Y600-T603 PolarHBondContact O-N 2.69Å; Y600-L604 HydrophobicContact CD1-CD1 4.4Å; Y600-L604 HydrophobicContact CD2-CD1 3.72Å; Y600-L604 HydrophobicContact CD2-CG 4.43Å; Y600-L604 HydrophobicContact CE1-CD1 3.88Å; Y600-L604 HydrophobicContact CE2-CD1 3.13Å; Y600-L604 HydrophobicContact CE2-CG 4.25Å; Y600-L604 HydrophobicContact CG-CD1 4.33Å; Y600-L604 WeakPolarHBondContact O-CB 3.4Å; Y600-L604 PolarHBondContact O-N 3.45Å; Y600-L604 WeakPolarHBondContact OH-CD1 3.43Å; Y600-W763 AromaticContact CE2-CZ2 3.99Å; Y600-W763 HydrophobicContact CE2-CZ2 3.99Å; Y600-W764 HydrophobicContact CD2-CB 4.12Å; Y600-W764 AromaticContact CD2-CD1 3.54Å; Y600-W764 HydrophobicContact CD2-CD2 4.38Å; Y600-W764 AromaticContact CD2-CG 3.74Å; Y600-W764 HydrophobicContact CD2-CG 3.74Å
601L98.1Very high96.9Very high0 Ų08.5 Ų8.50%05%0.047CC..Hα-helixtrans-63.8-46.6-178.2-71.4179.5000111.4I550 A566 L567 I570 G599 T603 S605I550-L601 HydrophobicContact CB-CD1 4.38Å; I550-L601 HydrophobicContact CD1-CD1 4.39Å; I550-L601 HydrophobicContact CG1-CD1 4.29Å; I550-L601 WeakPolarHBondContact O-CD1 3.46Å; I550-L601 WeakPolarHBondContact O-CD2 3.48Å; I550-L601 WeakPolarHBondContact O-CG 3.39Å; A566-L601 HydrophobicContact CB-CD1 4.49Å; A566-L601 HydrophobicContact CB-CD2 3.98Å; L567-L601 HydrophobicContact CD2-CD2 3.81Å; L567-L601 HydrophobicContact CG-CD2 3.93Å; I570-L601 HydrophobicContact CD1-CB 4.03Å; I570-L601 HydrophobicContact CD1-CD1 4.24Å; I570-L601 HydrophobicContact CD1-CD2 4.05Å; I570-L601 HydrophobicContact CD1-CG 4.34Å; G599-L601 PolarHBondContact O-N 3.49Å; L601-T603 VanDerWaalsContact C-N 3.33Å; L601-T603 PolarHBondContact O-N 2.89Å; L601-S605 WeakPolarHBondContact O-CB 3.49Å; L601-S605 PolarHBondContact O-N 3.14Å; L601-S605 PolarHBondContact O-OG 2.95Å
602A97.8Very high96.6Very high0 Ų09.3 Ų9.30%05%0.051CC..Hα-helixtrans-59.5-43.4178.400000111.8G599 S605 A606 I616 M647 C649G599-A602 PolarHBondContact O-N 3.35Å; A602-S605 PolarHBondContact O-OG 2.95Å; A602-A606 WeakPolarHBondContact O-CB 3.45Å; A602-A606 PolarHBondContact O-N 3.16Å; A602-A606 VanDerWaalsContact O-N 3.07Å; A602-I616 HydrophobicContact CB-CG2 3.89Å; A602-M647 HydrophobicContact CB-CB 4.32Å; A602-C649 HydrophobicContact CB-CB 4.07Å
603T97.6Very high96.4Very high1 Ų17.8 Ų7.81%0.0064%0.044CC..Hα-helixtrans-73.4-50.1-176.2-61.60000112.3G599 Y600 L601 A606 L607 W764 R768G599-T603 VanDerWaalsContact O-CB 3.29Å; G599-T603 WeakPolarHBondContact O-CB 3.49Å; G599-T603 PolarHBondContact O-N 2.81Å; G599-T603 PolarHBondContact O-OG1 2.9Å; Y600-T603 PolarHBondContact O-N 2.69Å; L601-T603 VanDerWaalsContact C-N 3.33Å; L601-T603 PolarHBondContact O-N 2.89Å; T603-A606 WeakPolarHBondContact O-CB 3.17Å; T603-A606 PolarHBondContact O-N 3.01Å; T603-L607 PolarHBondContact O-N 2.71Å; T603-L607 VanDerWaalsContact O-N 3.08Å; T603-W764 HydrophobicContact CG2-CE3 3.98Å; T603-W764 HydrophobicContact CG2-CZ3 4.25Å; T603-W764 VanDerWaalsContact OG1-CZ3 3.29Å; T603-W764 WeakPolarHBondContact OG1-CZ3 3.43Å; T603-R768 HydrophobicContact CG2-CG 4.12Å
604L97.4Very high96.3Very high4 Ų47.8 Ų7.82%0.0214%0.044CC..Hα-helixtrans-70-39.8-178.4-76-177.6000111.9L327 L567 Y600 A606 L607 A608 L767L327-L604 HydrophobicContact CD1-CB 4.34Å; L327-L604 HydrophobicContact CD1-CD2 4.09Å; L327-L604 HydrophobicContact CD2-CD2 3.96Å; L567-L604 HydrophobicContact CD1-CB 4.16Å; L567-L604 HydrophobicContact CD1-CD1 3.87Å; L567-L604 HydrophobicContact CD2-CB 3.7Å; Y600-L604 HydrophobicContact CD1-CD1 4.4Å; Y600-L604 HydrophobicContact CD2-CD1 3.72Å; Y600-L604 HydrophobicContact CD2-CG 4.43Å; Y600-L604 HydrophobicContact CE1-CD1 3.88Å; Y600-L604 HydrophobicContact CE2-CD1 3.13Å; Y600-L604 HydrophobicContact CE2-CG 4.25Å; Y600-L604 HydrophobicContact CG-CD1 4.33Å; Y600-L604 WeakPolarHBondContact O-CB 3.4Å; Y600-L604 PolarHBondContact O-N 3.45Å; Y600-L604 WeakPolarHBondContact OH-CD1 3.43Å; L604-A606 VanDerWaalsContact C-N 3.29Å; L604-A606 PolarHBondContact O-N 3.18Å; L604-L607 PolarHBondContact O-N 2.92Å; L604-A608 WeakPolarHBondContact O-CB 3.49Å; L604-A608 PolarHBondContact O-N 2.97Å; L604-L767 HydrophobicContact CD2-CD1 3.54Å
605S97.5Very high96.3Very high0 Ų06.5 Ų6.50%04%0.037CC..Hα-helixtrans-66-33.2174.565.50000112L601 A602 S609L601-S605 WeakPolarHBondContact O-CB 3.49Å; L601-S605 PolarHBondContact O-N 3.14Å; L601-S605 PolarHBondContact O-OG 2.95Å; A602-S605 PolarHBondContact O-OG 2.95Å; S605-S609 WeakPolarHBondContact O-CB 3.49Å; S605-S609 PolarHBondContact O-N 2.85Å; S605-S609 PolarHBondContact O-OG 3.13Å
606A97Very high96.3Very high0 Ų06.5 Ų6.50%04%0.037CC..Hα-helixtrans-60.8-48.5172.300000111.5A602 T603 L604 G610 A611 A614 M647 M771A602-A606 WeakPolarHBondContact O-CB 3.45Å; A602-A606 PolarHBondContact O-N 3.16Å; A602-A606 VanDerWaalsContact O-N 3.07Å; T603-A606 WeakPolarHBondContact O-CB 3.17Å; T603-A606 PolarHBondContact O-N 3.01Å; L604-A606 VanDerWaalsContact C-N 3.29Å; L604-A606 PolarHBondContact O-N 3.18Å; A606-G610 CarbonylContact O-C 3.54Å; A606-G610 WeakPolarHBondContact O-CA 3.38Å; A606-G610 PolarHBondContact O-N 3.13Å; A606-A611 HydrophobicContact CB-CB 3.88Å; A606-A611 PolarHBondContact O-N 3.47Å; A606-A614 HydrophobicContact CB-CB 3.91Å; A606-M647 HydrophobicContact CB-CB 4.29Å; A606-M647 HydrophobicContact CB-CG 3.6Å; A606-M771 HydrophobicContact CB-CG 4.23Å; A606-M771 HydrophobicContact CB-SD 3.56Å; A606-M771 VanDerWaalsContact CB-SD 3.56Å
607L96.6Very high96.4Very high4 Ų48.6 Ų8.62%0.0214%0.041CC..Hα-helixtrans-64.2-46.7177.6-179.259.2000111.9I93 L327 T603 L604 S609 G610 L767 L770 M771 L774I93-L607 WeakPolarHBondContact CD1-O 3.32Å; L327-L607 HydrophobicContact CD2-CB 3.88Å; L327-L607 HydrophobicContact CD2-CD2 3.73Å; L327-L607 HydrophobicContact CD2-CG 3.73Å; T603-L607 PolarHBondContact O-N 2.71Å; T603-L607 VanDerWaalsContact O-N 3.08Å; L604-L607 PolarHBondContact O-N 2.92Å; L607-S609 VanDerWaalsContact C-N 3.35Å; L607-S609 PolarHBondContact O-N 3.05Å; L607-G610 PolarHBondContact O-N 3.19Å; L607-L767 HydrophobicContact CD2-CB 4.32Å; L607-L767 HydrophobicContact CD2-CD1 4.49Å; L607-L770 HydrophobicContact CD1-CG 4.42Å; L607-L770 HydrophobicContact CD2-CD2 4.38Å; L607-M771 HydrophobicContact CB-CB 4.5Å; L607-M771 HydrophobicContact CB-CG 4.43Å; L607-M771 HydrophobicContact CD1-CB 4.43Å; L607-L774 HydrophobicContact CD1-CD1 3.88Å
608A97.3Very high96.3Very high0 Ų06.5 Ų6.50%03%0.034CC..Hα-helixtrans-67.9-32-17800000113I93 R326 L327 C571 L604I93-A608 VanDerWaalsContact CD1-O 3.24Å; I93-A608 WeakPolarHBondContact CD1-O 3.48Å; R326-A608 HydrophobicContact CB-CB 4.26Å; R326-A608 WeakPolarHBondContact CD-O 3.49Å; L327-A608 HydrophobicContact CD1-CB 4.41Å; L327-A608 HydrophobicContact CD2-CB 3.87Å; L327-A608 HydrophobicContact CG-CB 3.8Å; C571-A608 VanDerWaalsContact SG-CB 3.56Å; L604-A608 WeakPolarHBondContact O-CB 3.49Å; L604-A608 PolarHBondContact O-N 2.97Å
609S95.1Very high96.1Very high0 Ų07 Ų70%04%0.036CC..Hα-helixtrans-93.8-9.4177.9700000113.1I574 K578 S605 L607 A611I574-S609 WeakPolarHBondContact CD1-OG 3.38Å; K578-S609 WeakPolarHBondContact CE-O 3.21Å; K578-S609 PolarHBondContact NZ-O 3.41Å; S605-S609 WeakPolarHBondContact O-CB 3.49Å; S605-S609 PolarHBondContact O-N 2.85Å; S605-S609 PolarHBondContact O-OG 3.13Å; L607-S609 VanDerWaalsContact C-N 3.35Å; L607-S609 PolarHBondContact O-N 3.05Å; S609-A611 VanDerWaalsContact C-N 3.32Å; S609-A611 PolarHBondContact OG-N 2.78Å
610G92.8Very high95.9Very high11 Ų1112.2 Ų12.211%0.1137%0.07CC..THydrogen-bonded Turntrans6439.5-171.600000112.2A606 L607A606-G610 CarbonylContact O-C 3.54Å; A606-G610 WeakPolarHBondContact O-CA 3.38Å; A606-G610 PolarHBondContact O-N 3.13Å; L607-G610 PolarHBondContact O-N 3.19Å
611A93.5Very high95.7Very high3 Ų312.2 Ų12.23%0.0257%0.07CC..  trans-64.6156.6164.600000110A606 S609 I645 M647A606-A611 HydrophobicContact CB-CB 3.88Å; A606-A611 PolarHBondContact O-N 3.47Å; S609-A611 VanDerWaalsContact C-N 3.32Å; S609-A611 PolarHBondContact OG-N 2.78Å; A611-I645 HydrophobicContact CB-CB 4.11Å; A611-I645 HydrophobicContact CB-CG2 3.82Å; A611-M647 HydrophobicContact CB-CG 3.85Å; A611-M647 HydrophobicContact CB-SD 4.2Å
612D92.5Very high95.6Very high17 Ų1715.1 Ų15.19%0.0919%0.088CC..SBendtrans-91.3-27.3-170.2-62.9-90.3000113.3K636 Y644 I645 A775D612-K636 IonicContact OD1-NZ 3.33Å; D612-Y644 HydrophobicContact CB-CD1 3.81Å; D612-Y644 HydrophobicContact CB-CD2 3.63Å; D612-Y644 HydrophobicContact CB-CE1 3.45Å; D612-Y644 VanDerWaalsContact CB-CE1 3.45Å; D612-Y644 HydrophobicContact CB-CE2 3.25Å; D612-Y644 HydrophobicContact CB-CG 3.9Å; D612-Y644 VanDerWaalsContact CG-CD2 3.48Å; D612-Y644 WeakPolarHBondContact OD2-CA 3.48Å; D612-I645 PolarHBondContact N-O 3.45Å; D612-I645 PolarHBondContact OD2-N 2.79Å; D612-A775 VanDerWaalsContact O-CB 3.28Å; D612-A775 WeakPolarHBondContact O-CB 3.44Å
613N93.6Very high95.5Very high1 Ų117.5 Ų17.51%0.00510%0.102CC..EExtended strand (participates in β ladder)trans-151165.4172.4-161.911.9000111.3D629 Y644 I645 I646 M647 H777N613-D629 PolarHBondContact ND2-OD2 3.25Å; N613-Y644 HydrophobicContact CB-CE1 4.5Å; N613-I645 PolarHBondContact N-O 3.23Å; N613-I646 HydrophobicContact CB-CG1 4.44Å; N613-I646 WeakPolarHBondContact O-CA 3.46Å; N613-M647 PolarHBondContact O-N 3.42Å; N613-H777 PolarHBondContact ND2-NE2 3.36Å
614A96.1Very high95.3Very high0 Ų022.2 Ų22.20%013%0.127CC..EExtended strand (participates in β ladder)trans-145.3124.6172.200000112.2A606 M647 R768 M771A606-A614 HydrophobicContact CB-CB 3.91Å; A614-M647 CarbonylContact C-O 3.58Å; A614-M647 WeakPolarHBondContact CA-O 3.39Å; A614-M647 HydrophobicContact CB-CB 3.87Å; A614-R768 PolarHBondContact O-NH1 3.05Å; A614-R768 PolarHBondContact O-NH2 2.95Å; A614-M771 HydrophobicContact CB-CE 4.26Å; A614-M771 HydrophobicContact CB-SD 3.95Å
615Y97.4Very high95.1Very high4 Ų422.7 Ų22.72%0.01613%0.13CC..EExtended strand (participates in β ladder)trans-90.6126.8171.9-63.3-60.8000110.8F621 M626 D629 I646 M647 R648 C649 I661Y615-F621 HydrophobicContact CD1-CB 4.22Å; Y615-F621 AromaticContact CD1-CD1 3.85Å; Y615-F621 HydrophobicContact CD1-CD1 3.85Å; Y615-F621 AromaticContact CD1-CD2 3.68Å; Y615-F621 HydrophobicContact CD1-CD2 3.68Å; Y615-F621 HydrophobicContact CD1-CE1 4.12Å; Y615-F621 AromaticContact CD1-CE2 3.92Å; Y615-F621 HydrophobicContact CD1-CE2 3.92Å; Y615-F621 AromaticContact CD1-CG 3.65Å; Y615-F621 HydrophobicContact CD1-CG 3.65Å; Y615-F621 HydrophobicContact CD1-CZ 4.14Å; Y615-F621 HydrophobicContact CE1-CB 4.31Å; Y615-F621 AromaticContact CE1-CD2 3.83Å; Y615-F621 HydrophobicContact CE1-CD2 3.83Å; Y615-F621 HydrophobicContact CE1-CE2 4.31Å; Y615-F621 HydrophobicContact CE1-CG 4.04Å; Y615-F621 HydrophobicContact CG-CD1 4.47Å; Y615-F621 HydrophobicContact CG-CD2 4.37Å; Y615-F621 HydrophobicContact CG-CE1 4.29Å; Y615-F621 HydrophobicContact CG-CE2 4.15Å; Y615-F621 HydrophobicContact CG-CZ 4.11Å; Y615-M626 HydrophobicContact CE1-CG 4.38Å; Y615-M626 WeakPolarHBondContact OH-CG 3.16Å; Y615-D629 PolarHBondContact OH-OD2 3.36Å; Y615-I646 HydrophobicContact CD2-CG2 3.56Å; Y615-I646 HydrophobicContact CE2-CG2 3.55Å; Y615-M647 PolarHBondContact N-O 3.13Å; Y615-R648 WeakPolarHBondContact O-CA 3.49Å; Y615-C649 PolarHBondContact O-N 3.05Å; Y615-I661 HydrophobicContact CD2-CD1 3.97Å; Y615-I661 HydrophobicContact CE2-CD1 4.14Å; Y615-I661 HydrophobicContact CE2-CG2 4.37Å
616I97.3Very high95Very high1 Ų122.7 Ų22.71%0.00513%0.13CC..BIsolated β-bridgetrans-137163.2-176.563.2174.9000109.9A602 E618 E619 C649 W764 L765A602-I616 HydrophobicContact CB-CG2 3.89Å; I616-E618 VanDerWaalsContact C-N 3.35Å; I616-E618 WeakPolarHBondContact CB-OE2 3.22Å; I616-E618 HydrophobicContact CD1-CB 4.1Å; I616-E618 HydrophobicContact CG1-CB 4.45Å; I616-E619 HydrophobicContact CD1-CB 4.13Å; I616-E619 HydrophobicContact CG1-CB 3.78Å; I616-C649 HydrophobicContact CG2-CB 4.49Å; I616-W764 HydrophobicContact CD1-CH2 4.04Å; I616-W764 HydrophobicContact CD1-CZ3 3.85Å; I616-L765 HydrophobicContact CD1-CD2 3.82Å
617F96.6Very high94.9Very high63 Ų6326.3 Ų26.328%0.27615%0.146SC..THydrogen-bonded Turntrans-71.6-35.1-178.9172.4-104.6000111.7Y597 E619 R756 L758Y597-F617 HydrophobicContact CD1-CB 4.39Å; Y597-F617 HydrophobicContact CD1-CD1 4.18Å; Y597-F617 AromaticContact CD1-CD2 3.59Å; Y597-F617 HydrophobicContact CD1-CD2 3.59Å; Y597-F617 HydrophobicContact CD1-CE1 4.42Å; Y597-F617 AromaticContact CD1-CE2 3.86Å; Y597-F617 HydrophobicContact CD1-CE2 3.86Å; Y597-F617 AromaticContact CD1-CG 3.77Å; Y597-F617 HydrophobicContact CD1-CG 3.77Å; Y597-F617 HydrophobicContact CD1-CZ 4.29Å; Y597-F617 HydrophobicContact CE1-CD2 4.2Å; Y597-F617 HydrophobicContact CE1-CE2 4.21Å; Y597-F617 HydrophobicContact CG-CG 4.45Å; Y597-F617 WeakPolarHBondContact O-CB 3.08Å; F617-E619 PolarHBondContact O-N 3.48Å; F617-R756 VanDerWaalsContact CZ-CD 3.42Å; F617-L758 HydrophobicContact CD1-CD1 4.09Å; F617-L758 HydrophobicContact CE1-CD1 4.13Å
618E95.6Very high94.8Very high17 Ų1730.9 Ų30.98%0.07916%0.162CC..THydrogen-bonded Turntrans-68.8-14.3-176-60.58915900113.9C598 G599 I616 W764 L765C598-E618 WeakPolarHBondContact CA-OE1 3.45Å; G599-E618 WeakPolarHBondContact CA-OE2 3.21Å; G599-E618 PolarHBondContact N-OE1 3.48Å; G599-E618 PolarHBondContact N-OE2 2.97Å; G599-E618 VanDerWaalsContact N-OE2 3.14Å; I616-E618 VanDerWaalsContact C-N 3.35Å; I616-E618 WeakPolarHBondContact CB-OE2 3.22Å; I616-E618 HydrophobicContact CD1-CB 4.1Å; I616-E618 HydrophobicContact CG1-CB 4.45Å; E618-W764 VanDerWaalsContact CD-CH2 3.42Å; E618-W764 HydrophobicContact CG-CH2 4.12Å; E618-W764 HydrophobicContact CG-CZ2 4.41Å; E618-W764 VanDerWaalsContact OE1-CH2 3.26Å; E618-W764 WeakPolarHBondContact OE1-CH2 3.19Å; E618-W764 WeakPolarHBondContact OE1-CZ2 3.14Å; E618-L765 HydrophobicContact CB-CD1 4.26Å; E618-L765 HydrophobicContact CB-CD2 3.98Å
619E93.7Very high94.6Very high14 Ų1430.9 Ų30.97%0.06516%0.162CC..BIsolated β-bridgetrans-128.192.8-179.1-169.1-173.5112.300108.5I616 F617 R768 R772 Y781I616-E619 HydrophobicContact CD1-CB 4.13Å; I616-E619 HydrophobicContact CG1-CB 3.78Å; F617-E619 PolarHBondContact O-N 3.48Å; E619-R768 IonicContact OE1-CZ 2.98Å; E619-R768 IonicContact OE1-NH2 2.64Å; E619-R768 PolarHBondContact OE1-NH2 3.04Å; E619-R768 IonicContact OE2-CZ 3.62Å; E619-R768 VanDerWaalsContact OE2-CZ 3.28Å; E619-R768 IonicContact OE2-NE 3.02Å; E619-R768 PolarHBondContact OE2-NE 3.32Å; E619-R768 IonicContact OE2-NH2 3.04Å; E619-R768 PolarHBondContact OE2-NH2 3.32Å; E619-R772 IonicContact OE1-CZ 3.4Å; E619-R772 IonicContact OE1-NH2 2.71Å; E619-R772 PolarHBondContact OE1-NH2 2.65Å; E619-R772 IonicContact OE2-CZ 3.66Å; E619-R772 IonicContact OE2-NH2 3.04Å; E619-R772 PolarHBondContact OE2-NH2 3.07Å; E619-Y781 WeakPolarHBondContact OE1-CD2 3.34Å
620P92.9Very high94.6Very high109 Ų10931.2 Ų31.271%0.70816%0.164SC*.  trans-57.8141.5-179.1-24.934.4000111.9
621F94.3Very high94.7Very high7 Ų736.2 Ų36.23%0.03119%0.185CC..  trans-137151.217959.3-80.5000110.1Y615 M626 A652 N653 Y656 I661 Y781Y615-F621 HydrophobicContact CD1-CB 4.22Å; Y615-F621 AromaticContact CD1-CD1 3.85Å; Y615-F621 HydrophobicContact CD1-CD1 3.85Å; Y615-F621 AromaticContact CD1-CD2 3.68Å; Y615-F621 HydrophobicContact CD1-CD2 3.68Å; Y615-F621 HydrophobicContact CD1-CE1 4.12Å; Y615-F621 AromaticContact CD1-CE2 3.92Å; Y615-F621 HydrophobicContact CD1-CE2 3.92Å; Y615-F621 AromaticContact CD1-CG 3.65Å; Y615-F621 HydrophobicContact CD1-CG 3.65Å; Y615-F621 HydrophobicContact CD1-CZ 4.14Å; Y615-F621 HydrophobicContact CE1-CB 4.31Å; Y615-F621 AromaticContact CE1-CD2 3.83Å; Y615-F621 HydrophobicContact CE1-CD2 3.83Å; Y615-F621 HydrophobicContact CE1-CE2 4.31Å; Y615-F621 HydrophobicContact CE1-CG 4.04Å; Y615-F621 HydrophobicContact CG-CD1 4.47Å; Y615-F621 HydrophobicContact CG-CD2 4.37Å; Y615-F621 HydrophobicContact CG-CE1 4.29Å; Y615-F621 HydrophobicContact CG-CE2 4.15Å; Y615-F621 HydrophobicContact CG-CZ 4.11Å; F621-M626 HydrophobicContact CD2-CE 4.01Å; F621-M626 HydrophobicContact CD2-CG 4.27Å; F621-M626 HydrophobicContact CD2-SD 4.43Å; F621-M626 HydrophobicContact CE2-CE 4.04Å; F621-M626 HydrophobicContact CE2-SD 4.32Å; F621-A652 HydrophobicContact CE1-CB 4.02Å; F621-A652 HydrophobicContact CZ-CB 4.29Å; F621-N653 HydrophobicContact CE1-CB 4.1Å; F621-N653 HydrophobicContact CZ-CB 3.75Å; F621-Y656 HydrophobicContact CD2-CD2 4.06Å; F621-Y656 AromaticContact CE2-CD2 3.66Å; F621-Y656 HydrophobicContact CE2-CD2 3.66Å; F621-Y656 HydrophobicContact CE2-CG 4.21Å; F621-Y656 HydrophobicContact CZ-CD2 4.21Å; F621-Y656 WeakPolarHBondContact O-CE2 3.25Å; F621-I661 HydrophobicContact CE2-CD1 4.43Å; F621-Y781 HydrophobicContact CB-CD1 3.99Å; F621-Y781 HydrophobicContact CB-CE1 3.5Å; F621-Y781 VanDerWaalsContact CB-CE1 3.5Å
622T95.2Very high94.6Very high62 Ų6236.8 Ų36.838%0.3819%0.188SC..  trans-116172.9-177.267.70000111.6D624 D625 M626T622-D624 PolarHBondContact O-N 3.09Å; T622-D624 PolarHBondContact OG1-N 3.39Å; T622-D625 WeakPolarHBondContact CB-OD2 3.42Å; T622-D625 PolarHBondContact N-OD2 3.46Å; T622-D625 PolarHBondContact O-N 3.43Å; T622-D625 PolarHBondContact OG1-N 3.13Å; T622-D625 PolarHBondContact OG1-OD2 2.91Å; T622-M626 PolarHBondContact O-N 2.96Å; T622-M626 VanDerWaalsContact O-N 3.1Å
623V95.2Very high94.6Very high50 Ų5036 Ų3630%0.30318%0.184SC..Hα-helixtrans-59.6-35.8170.4178.30000111.6D625 M626 K627 Y656 F660 L664V623-D625 VanDerWaalsContact C-N 3.34Å; V623-D625 PolarHBondContact O-N 3.1Å; V623-M626 HydrophobicContact CG2-CE 4.2Å; V623-M626 WeakPolarHBondContact O-CB 3.35Å; V623-M626 PolarHBondContact O-N 2.87Å; V623-K627 HydrophobicContact CG1-CD 4.19Å; V623-K627 HydrophobicContact CG1-CG 4.41Å; V623-K627 WeakPolarHBondContact O-CG 3.26Å; V623-K627 PolarHBondContact O-N 3.44Å; V623-Y656 HydrophobicContact CG2-CE1 4.07Å; V623-F660 HydrophobicContact CG2-CZ 4.45Å; V623-L664 HydrophobicContact CG1-CD2 4.32Å
624D94.4Very high94.5Very high100 Ų10036.5 Ų36.554%0.53519%0.188SC..Hα-helixtrans-68.4-35.2178.7-69.5-41.3000112.5T622 K627 R628T622-D624 PolarHBondContact O-N 3.09Å; T622-D624 PolarHBondContact OG1-N 3.39Å; D624-K627 PolarHBondContact O-N 3.25Å; D624-R628 WeakPolarHBondContact O-CG 3.4Å; D624-R628 PolarHBondContact O-N 2.93Å; D624-R628 PolarHBondContact O-NE 2.8Å
625D93.6Very high94.3Very high13 Ų1344.2 Ų44.27%0.0722%0.217CC..Hα-helixtrans-65.8-45.4172.5-58.6-61.9000111.5T622 V623 K627 R628 D629 Y781T622-D625 WeakPolarHBondContact CB-OD2 3.42Å; T622-D625 PolarHBondContact N-OD2 3.46Å; T622-D625 PolarHBondContact O-N 3.43Å; T622-D625 PolarHBondContact OG1-N 3.13Å; T622-D625 PolarHBondContact OG1-OD2 2.91Å; V623-D625 VanDerWaalsContact C-N 3.34Å; V623-D625 PolarHBondContact O-N 3.1Å; D625-K627 VanDerWaalsContact C-N 3.28Å; D625-K627 PolarHBondContact O-N 2.62Å; D625-R628 WeakPolarHBondContact O-CA 3.49Å; D625-R628 WeakPolarHBondContact O-CB 3.03Å; D625-R628 PolarHBondContact O-N 3.25Å; D625-R628 VanDerWaalsContact O-N 3.09Å; D625-R628 IonicContact OD1-CZ 2.96Å; D625-R628 IonicContact OD1-NH1 2.73Å; D625-R628 PolarHBondContact OD1-NH1 3.48Å; D625-R628 IonicContact OD1-NH2 2.66Å; D625-R628 PolarHBondContact OD1-NH2 2.89Å; D625-D629 PolarHBondContact O-N 3.33Å; D625-Y781 HydrophobicContact CB-CD1 4.01Å; D625-Y781 HydrophobicContact CB-CE1 3.16Å
626M95.2Very high93.8Very high0 Ų045.5 Ų45.50%022%0.223CC..Hα-helixtrans-58-40.3175-80.1-172.3-92.300112.1Y615 F621 T622 V623 D629 V630 Y656 F660 I661 L664 F665Y615-M626 HydrophobicContact CE1-CG 4.38Å; Y615-M626 WeakPolarHBondContact OH-CG 3.16Å; F621-M626 HydrophobicContact CD2-CE 4.01Å; F621-M626 HydrophobicContact CD2-CG 4.27Å; F621-M626 HydrophobicContact CD2-SD 4.43Å; F621-M626 HydrophobicContact CE2-CE 4.04Å; F621-M626 HydrophobicContact CE2-SD 4.32Å; T622-M626 PolarHBondContact O-N 2.96Å; T622-M626 VanDerWaalsContact O-N 3.1Å; V623-M626 HydrophobicContact CG2-CE 4.2Å; V623-M626 WeakPolarHBondContact O-CB 3.35Å; V623-M626 PolarHBondContact O-N 2.87Å; M626-D629 WeakPolarHBondContact O-CB 3.46Å; M626-D629 PolarHBondContact O-N 3.18Å; M626-V630 WeakPolarHBondContact O-CG2 3.34Å; M626-V630 PolarHBondContact O-N 3.17Å; M626-Y656 HydrophobicContact CE-CD1 4Å; M626-Y656 HydrophobicContact CE-CD2 3.66Å; M626-Y656 HydrophobicContact CE-CE1 4.4Å; M626-Y656 HydrophobicContact CE-CE2 4.08Å; M626-Y656 HydrophobicContact CE-CG 3.62Å; M626-F660 HydrophobicContact CE-CE1 4.09Å; M626-F660 HydrophobicContact SD-CE1 4.44Å; M626-I661 HydrophobicContact SD-CD1 4.32Å; M626-I661 HydrophobicContact SD-CG1 3.79Å; M626-I661 HydrophobicContact SD-CG2 4.34Å; M626-L664 HydrophobicContact CB-CD2 3.76Å; M626-L664 HydrophobicContact CG-CD2 4.46Å; M626-L664 HydrophobicContact SD-CD2 3.89Å; M626-F665 HydrophobicContact CB-CE1 3.92Å; M626-F665 HydrophobicContact CG-CE1 4.16Å
627K94.2Very high93.4Very high77 Ų7745.6 Ų45.634%0.33522%0.223SC..Hα-helixtrans-65.7-40.4174.6-73.6176.569.7177.90112.1V623 D624 D625 D629 V630 Q631V623-K627 HydrophobicContact CG1-CD 4.19Å; V623-K627 HydrophobicContact CG1-CG 4.41Å; V623-K627 WeakPolarHBondContact O-CG 3.26Å; V623-K627 PolarHBondContact O-N 3.44Å; D624-K627 PolarHBondContact O-N 3.25Å; D625-K627 VanDerWaalsContact C-N 3.28Å; D625-K627 PolarHBondContact O-N 2.62Å; K627-D629 VanDerWaalsContact C-N 3.27Å; K627-D629 PolarHBondContact O-N 3.37Å; K627-V630 WeakPolarHBondContact O-CB 3.2Å; K627-V630 PolarHBondContact O-N 2.87Å; K627-Q631 WeakPolarHBondContact O-CG 3.39Å; K627-Q631 PolarHBondContact O-N 3.49Å; K627-Q631 VanDerWaalsContact O-N 3.09Å
628R93.9Very high92.9Very high99 Ų9949.9 Ų49.937%0.37424%0.242SC..Hα-helixtrans-59.9-40.1172.2-78.7-179.5-101139.7-6.8111.2D624 D625 Q631 V632D624-R628 WeakPolarHBondContact O-CG 3.4Å; D624-R628 PolarHBondContact O-N 2.93Å; D624-R628 PolarHBondContact O-NE 2.8Å; D625-R628 WeakPolarHBondContact O-CA 3.49Å; D625-R628 WeakPolarHBondContact O-CB 3.03Å; D625-R628 PolarHBondContact O-N 3.25Å; D625-R628 VanDerWaalsContact O-N 3.09Å; D625-R628 IonicContact OD1-CZ 2.96Å; D625-R628 IonicContact OD1-NH1 2.73Å; D625-R628 PolarHBondContact OD1-NH1 3.48Å; D625-R628 IonicContact OD1-NH2 2.66Å; D625-R628 PolarHBondContact OD1-NH2 2.89Å; R628-Q631 WeakPolarHBondContact O-CB 3.22Å; R628-Q631 PolarHBondContact O-N 2.93Å; R628-V632 WeakPolarHBondContact O-CG2 3.37Å; R628-V632 PolarHBondContact O-N 3.12Å
629D94Very high92.3Very high0 Ų053.2 Ų53.20%027%0.267CS..Hα-helixtrans-64.8-42.8176.8-73.6-2.9000111.8N613 Y615 D625 M626 K627 Q631 V632 I633 F665 H777 S779 Y781N613-D629 PolarHBondContact ND2-OD2 3.25Å; Y615-D629 PolarHBondContact OH-OD2 3.36Å; D625-D629 PolarHBondContact O-N 3.33Å; M626-D629 WeakPolarHBondContact O-CB 3.46Å; M626-D629 PolarHBondContact O-N 3.18Å; K627-D629 VanDerWaalsContact C-N 3.27Å; K627-D629 PolarHBondContact O-N 3.37Å; D629-Q631 VanDerWaalsContact C-N 3.28Å; D629-Q631 PolarHBondContact O-N 3.37Å; D629-V632 WeakPolarHBondContact O-CB 3.48Å; D629-V632 PolarHBondContact O-N 3.46Å; D629-V632 VanDerWaalsContact O-N 3.11Å; D629-I633 WeakPolarHBondContact O-CG1 3.05Å; D629-I633 PolarHBondContact O-N 3.06Å; D629-F665 HydrophobicContact CB-CZ 4.16Å; D629-H777 IonicContact OD1-CE1 2.94Å; D629-H777 PolarHBondContact OD1-CE1 2.92Å; D629-H777 IonicContact OD1-NE2 3.66Å; D629-H777 PolarHBondContact OD1-NE2 3.24Å; D629-H777 IonicContact OD2-NE2 3.84Å; D629-S779 PolarHBondContact OD1-OG 3.02Å; D629-Y781 PolarHBondContact OD2-OH 3.24Å
630V95.3Very high91.7Very high7 Ų754.7 Ų54.74%0.04229%0.286CS..Hα-helixtrans-54.8-43.8171.91680000111.6M626 K627 I633 A634 F665 E668 F673M626-V630 WeakPolarHBondContact O-CG2 3.34Å; M626-V630 PolarHBondContact O-N 3.17Å; K627-V630 WeakPolarHBondContact O-CB 3.2Å; K627-V630 PolarHBondContact O-N 2.87Å; V630-I633 PolarHBondContact O-N 3.46Å; V630-A634 WeakPolarHBondContact O-CB 3.36Å; V630-A634 PolarHBondContact O-N 2.88Å; V630-F665 HydrophobicContact CG2-CB 4.34Å; V630-F665 HydrophobicContact CG2-CD1 3.76Å; V630-F665 HydrophobicContact CG2-CD2 3.89Å; V630-F665 HydrophobicContact CG2-CE1 3.93Å; V630-F665 HydrophobicContact CG2-CE2 4.02Å; V630-F665 HydrophobicContact CG2-CG 3.73Å; V630-F665 HydrophobicContact CG2-CZ 4.04Å; V630-E668 HydrophobicContact CB-CB 4.47Å; V630-E668 HydrophobicContact CG1-CB 3.86Å; V630-E668 HydrophobicContact CG2-CB 4.26Å; V630-F673 HydrophobicContact CB-CZ 4.48Å; V630-F673 HydrophobicContact CG1-CE1 4.3Å; V630-F673 HydrophobicContact CG1-CZ 3.94Å; V630-F673 HydrophobicContact CG2-CZ 4.44Å
631Q93.6Very high91.1Very high116 Ų11651.2 Ų51.254%0.54226%0.263SS..Hα-helixtrans-65.7-39.9177-65.8171.6-0.300112.4K627 R628 D629 R635K627-Q631 WeakPolarHBondContact O-CG 3.39Å; K627-Q631 PolarHBondContact O-N 3.49Å; K627-Q631 VanDerWaalsContact O-N 3.09Å; R628-Q631 WeakPolarHBondContact O-CB 3.22Å; R628-Q631 PolarHBondContact O-N 2.93Å; D629-Q631 VanDerWaalsContact C-N 3.28Å; D629-Q631 PolarHBondContact O-N 3.37Å; Q631-R635 WeakPolarHBondContact O-CG 3.49Å; Q631-R635 PolarHBondContact O-N 2.86Å
632V91.6Very high90.6Very high15 Ų1554.6 Ų54.69%0.09128%0.279CS..Hα-helixtrans-62-44.9174.4172.20000110.6R628 D629 R635 K636R628-V632 WeakPolarHBondContact O-CG2 3.37Å; R628-V632 PolarHBondContact O-N 3.12Å; D629-V632 WeakPolarHBondContact O-CB 3.48Å; D629-V632 PolarHBondContact O-N 3.46Å; D629-V632 VanDerWaalsContact O-N 3.11Å; V632-R635 PolarHBondContact O-N 3.34Å; V632-K636 HydrophobicContact CG1-CD 4.22Å; V632-K636 PolarHBondContact O-N 2.81Å
633I93.3Very high90.3Very high0 Ų052.8 Ų52.80%027%0.265CS..Hα-helixtrans-61.4-50178.2-64.8164.3000110.2V588 D629 V630 R635 K636 M637 Y644 I646 F665 F673V588-I633 HydrophobicContact CG1-CD1 4.34Å; V588-I633 HydrophobicContact CG2-CD1 4.29Å; V588-I633 HydrophobicContact CG2-CG2 3.59Å; D629-I633 WeakPolarHBondContact O-CG1 3.05Å; D629-I633 PolarHBondContact O-N 3.06Å; V630-I633 PolarHBondContact O-N 3.46Å; I633-R635 VanDerWaalsContact C-N 3.27Å; I633-R635 PolarHBondContact O-N 2.67Å; I633-K636 PolarHBondContact O-N 3.23Å; I633-M637 HydrophobicContact CG2-CE 4.17Å; I633-M637 HydrophobicContact CG2-CG 4.03Å; I633-M637 WeakPolarHBondContact O-CB 3.4Å; I633-M637 WeakPolarHBondContact O-CG 3.19Å; I633-M637 PolarHBondContact O-N 2.83Å; I633-Y644 HydrophobicContact CD1-CD1 3.7Å; I633-Y644 HydrophobicContact CD1-CE1 3.76Å; I633-Y644 HydrophobicContact CD1-CG 4.2Å; I633-Y644 HydrophobicContact CG1-CD1 3.62Å; I633-Y644 HydrophobicContact CG1-CD2 3.78Å; I633-Y644 HydrophobicContact CG1-CE1 3.6Å; I633-Y644 HydrophobicContact CG1-CE2 3.77Å; I633-Y644 HydrophobicContact CG1-CG 3.7Å; I633-Y644 HydrophobicContact CG2-CD2 4.49Å; I633-Y644 HydrophobicContact CG2-CG 4.3Å; I633-I646 HydrophobicContact CD1-CD1 4.2Å; I633-F665 HydrophobicContact CD1-CD2 3.96Å; I633-F665 HydrophobicContact CD1-CE2 3.55Å; I633-F673 HydrophobicContact CB-CD1 4.39Å; I633-F673 HydrophobicContact CB-CE1 3.81Å; I633-F673 HydrophobicContact CB-CZ 4.19Å; I633-F673 HydrophobicContact CD1-CZ 4.48Å; I633-F673 HydrophobicContact CG2-CD1 3.53Å; I633-F673 HydrophobicContact CG2-CE1 3.41Å; I633-F673 VanDerWaalsContact CG2-CE1 3.41Å; I633-F673 HydrophobicContact CG2-CE2 4.41Å; I633-F673 HydrophobicContact CG2-CG 4.08Å; I633-F673 HydrophobicContact CG2-CZ 3.87Å
634A92.3Very high90.2Very high12 Ų1250.4 Ų50.410%0.09925%0.25CS..Hα-helixtrans-58.1-40.5179.700000111.8V630 K638 N672 F673V630-A634 WeakPolarHBondContact O-CB 3.36Å; V630-A634 PolarHBondContact O-N 2.88Å; A634-K638 WeakPolarHBondContact O-CG 2.9Å; A634-K638 PolarHBondContact O-N 3.25Å; A634-K638 VanDerWaalsContact O-N 3.07Å; A634-N672 HydrophobicContact CB-CB 4.11Å; A634-F673 HydrophobicContact CB-CE1 4.29Å
635R90Very high90.2Very high163 Ų16345.6 Ų45.662%0.61523%0.225SC*.Hα-helixtrans-64-48.5174.9-74.9-173.5-68.1161.2-5112.5Q631 V632 I633 M637 K638 S639Q631-R635 WeakPolarHBondContact O-CG 3.49Å; Q631-R635 PolarHBondContact O-N 2.86Å; V632-R635 PolarHBondContact O-N 3.34Å; I633-R635 VanDerWaalsContact C-N 3.27Å; I633-R635 PolarHBondContact O-N 2.67Å; R635-M637 VanDerWaalsContact C-N 3.32Å; R635-M637 PolarHBondContact O-N 3.48Å; R635-K638 WeakPolarHBondContact O-CB 3.43Å; R635-K638 PolarHBondContact O-N 3.17Å; R635-S639 PolarHBondContact O-N 3.26Å; R635-S639 VanDerWaalsContact O-N 3.09Å
636K87.9Confident90.3Very high30 Ų3045 Ų4513%0.1322%0.222CC..Hα-helixtrans-60.2-41.2177-79.2-179.7165.5-170.60112.1D612 V632 I633 K638 S639 G640 V641 Y644 A775 G776D612-K636 IonicContact OD1-NZ 3.33Å; V632-K636 HydrophobicContact CG1-CD 4.22Å; V632-K636 PolarHBondContact O-N 2.81Å; I633-K636 PolarHBondContact O-N 3.23Å; K636-K638 VanDerWaalsContact C-N 3.31Å; K636-K638 PolarHBondContact O-N 2.74Å; K636-S639 PolarHBondContact O-N 2.85Å; K636-S639 PolarHBondContact O-OG 2.99Å; K636-G640 PolarHBondContact O-N 3.1Å; K636-V641 HydrophobicContact CB-CB 4.2Å; K636-V641 HydrophobicContact CB-CG2 4Å; K636-V641 VanDerWaalsContact O-CB 3.25Å; K636-V641 WeakPolarHBondContact O-CB 3.43Å; K636-V641 WeakPolarHBondContact O-CG2 3.25Å; K636-V641 PolarHBondContact O-N 3.36Å; K636-V641 VanDerWaalsContact O-N 3.1Å; K636-Y644 HydrophobicContact CD-CD2 4.2Å; K636-Y644 HydrophobicContact CD-CE2 3.81Å; K636-A775 PolarHBondContact NZ-O 2.86Å; K636-G776 WeakPolarHBondContact CE-O 3.41Å; K636-G776 PolarHBondContact NZ-O 3Å
637M88.5Confident90.4Very high3 Ų345 Ų452%0.01522%0.222CC..Hα-helixtrans-66.7-33.3178.6-67.4-76.2176.800112.3R586 V588 I633 R635 G640 V641 R643R586-M637 HydrophobicContact CB-SD 3.97Å; R586-M637 HydrophobicContact CG-CB 4.48Å; R586-M637 HydrophobicContact CG-SD 4.12Å; V588-M637 HydrophobicContact CG2-CE 4.43Å; I633-M637 HydrophobicContact CG2-CE 4.17Å; I633-M637 HydrophobicContact CG2-CG 4.03Å; I633-M637 WeakPolarHBondContact O-CB 3.4Å; I633-M637 WeakPolarHBondContact O-CG 3.19Å; I633-M637 PolarHBondContact O-N 2.83Å; R635-M637 VanDerWaalsContact C-N 3.32Å; R635-M637 PolarHBondContact O-N 3.48Å; M637-G640 PolarHBondContact O-N 3.13Å; M637-V641 WeakPolarHBondContact CA-O 3.49Å; M637-R643 VanDerWaalsContact CE-C 3.45Å
638K86.5Confident90.6Very high154 Ų15441.7 Ų41.767%0.6721%0.207SC*.Hα-helixtrans-68.6-34172.1-75.6176.8-178-177.60112.5A634 R635 K636 G640A634-K638 WeakPolarHBondContact O-CG 2.9Å; A634-K638 PolarHBondContact O-N 3.25Å; A634-K638 VanDerWaalsContact O-N 3.07Å; R635-K638 WeakPolarHBondContact O-CB 3.43Å; R635-K638 PolarHBondContact O-N 3.17Å; K636-K638 VanDerWaalsContact C-N 3.31Å; K636-K638 PolarHBondContact O-N 2.74Å; K638-G640 PolarHBondContact O-N 2.88Å
639S82.1Confident90.8Very high87 Ų8737 Ų3761%0.60819%0.189SC*.THydrogen-bonded Turntrans-79.8617771.40000114.3R635 K636R635-S639 PolarHBondContact O-N 3.26Å; R635-S639 VanDerWaalsContact O-N 3.09Å; K636-S639 PolarHBondContact O-N 2.85Å; K636-S639 PolarHBondContact O-OG 2.99Å
640G81.6Confident90.9Very high45 Ų4539.9 Ų39.946%0.46420%0.203SC..THydrogen-bonded Turntrans110.2-7.8172.600000115.4K636 M637 K638 Q642K636-G640 PolarHBondContact O-N 3.1Å; M637-G640 PolarHBondContact O-N 3.13Å; K638-G640 PolarHBondContact O-N 2.88Å; G640-Q642 PolarHBondContact O-N 2.76Å; G640-Q642 PolarHBondContact O-NE2 3.39Å
641V81.2Confident91Very high35 Ų3545 Ų4521%0.21222%0.221CC..  trans-61.5132.6174.5179.60000109.2K636 M637 R643K636-V641 HydrophobicContact CB-CB 4.2Å; K636-V641 HydrophobicContact CB-CG2 4Å; K636-V641 VanDerWaalsContact O-CB 3.25Å; K636-V641 WeakPolarHBondContact O-CB 3.43Å; K636-V641 WeakPolarHBondContact O-CG2 3.25Å; K636-V641 PolarHBondContact O-N 3.36Å; K636-V641 VanDerWaalsContact O-N 3.1Å; M637-V641 WeakPolarHBondContact CA-O 3.49Å; V641-R643 WeakPolarHBondContact CG1-O 3.27Å
642Q83.1Confident91.2Very high79 Ų7939.8 Ų39.837%0.36920%0.198SC..  trans-98.6-22.1-177.4-61.7-56.7-48.300113.4R586 R587 G640R586-Q642 WeakPolarHBondContact CA-O 3.16Å; R586-Q642 PolarHBondContact N-O 3.5Å; R587-Q642 PolarHBondContact N-O 3.06Å; G640-Q642 PolarHBondContact O-N 2.76Å; G640-Q642 PolarHBondContact O-NE2 3.39Å
643R89.7Confident91.4Very high23 Ų2341.1 Ų41.19%0.08721%0.205CC..EExtended strand (participates in β ladder)trans-138.4150.8-175.666.6171.4-163.877.6-3.8111.8D91 A581 R587 M637 V641D91-R643 IonicContact OD1-CZ 2.69Å; D91-R643 VanDerWaalsContact OD1-CZ 3.22Å; D91-R643 IonicContact OD1-NE 3.72Å; D91-R643 PolarHBondContact OD1-NE 3.31Å; D91-R643 IonicContact OD1-NH2 2.94Å; D91-R643 PolarHBondContact OD1-NH2 2.84Å; D91-R643 IonicContact OD2-CZ 3.1Å; D91-R643 IonicContact OD2-NE 2.71Å; D91-R643 PolarHBondContact OD2-NE 2.81Å; D91-R643 IonicContact OD2-NH2 3.53Å; A581-R643 HydrophobicContact CB-CB 3.89Å; R587-R643 CarbonylContact O-C 3.48Å; R587-R643 VanDerWaalsContact O-CA 3.25Å; R587-R643 WeakPolarHBondContact O-CA 3.49Å; M637-R643 VanDerWaalsContact CE-C 3.45Å; V641-R643 WeakPolarHBondContact CG1-O 3.27Å
644Y92.1Very high91.5Very high0 Ų048.2 Ų48.20%024%0.238CC..EExtended strand (participates in β ladder)trans-137.1133.8170.6-161.3-89.2000109.2R587 V588 F589 D612 N613 I633 K636 I646 H777R587-Y644 PolarHBondContact O-N 3.28Å; V588-Y644 CarbonylContact C-O 3.6Å; V588-Y644 VanDerWaalsContact CA-O 3.31Å; V588-Y644 WeakPolarHBondContact CA-O 3.29Å; V588-Y644 HydrophobicContact CG1-CD1 4.44Å; F589-Y644 PolarHBondContact N-O 2.98Å; D612-Y644 HydrophobicContact CB-CD1 3.81Å; D612-Y644 HydrophobicContact CB-CD2 3.63Å; D612-Y644 HydrophobicContact CB-CE1 3.45Å; D612-Y644 VanDerWaalsContact CB-CE1 3.45Å; D612-Y644 HydrophobicContact CB-CE2 3.25Å; D612-Y644 HydrophobicContact CB-CG 3.9Å; D612-Y644 VanDerWaalsContact CG-CD2 3.48Å; D612-Y644 WeakPolarHBondContact OD2-CA 3.48Å; N613-Y644 HydrophobicContact CB-CE1 4.5Å; I633-Y644 HydrophobicContact CD1-CD1 3.7Å; I633-Y644 HydrophobicContact CD1-CE1 3.76Å; I633-Y644 HydrophobicContact CD1-CG 4.2Å; I633-Y644 HydrophobicContact CG1-CD1 3.62Å; I633-Y644 HydrophobicContact CG1-CD2 3.78Å; I633-Y644 HydrophobicContact CG1-CE1 3.6Å; I633-Y644 HydrophobicContact CG1-CE2 3.77Å; I633-Y644 HydrophobicContact CG1-CG 3.7Å; I633-Y644 HydrophobicContact CG2-CD2 4.49Å; I633-Y644 HydrophobicContact CG2-CG 4.3Å; K636-Y644 HydrophobicContact CD-CD2 4.2Å; K636-Y644 HydrophobicContact CD-CE2 3.81Å; Y644-I646 HydrophobicContact CD1-CD1 4.12Å; Y644-I646 HydrophobicContact CD1-CG1 3.71Å; Y644-I646 HydrophobicContact CE1-CD1 3.95Å; Y644-I646 HydrophobicContact CE1-CG1 3.59Å; Y644-H777 PolarHBondContact OH-CE1 3Å; Y644-H777 PolarHBondContact OH-ND1 3.31Å
645I94.1Very high91.6Very high0 Ų053.6 Ų53.60%027%0.265CS..EExtended strand (participates in β ladder)trans-119.2129.7-179.5-61.4-178.4000109.7I574 K578 F589 V591 A611 D612 N613 M647I574-I645 HydrophobicContact CG2-CD1 3.91Å; K578-I645 HydrophobicContact CG-CD1 3.62Å; F589-I645 HydrophobicContact CB-CG1 4.4Å; F589-I645 WeakPolarHBondContact O-CA 3.37Å; V591-I645 HydrophobicContact CG2-CG2 4.07Å; A611-I645 HydrophobicContact CB-CB 4.11Å; A611-I645 HydrophobicContact CB-CG2 3.82Å; D612-I645 PolarHBondContact N-O 3.45Å; D612-I645 PolarHBondContact OD2-N 2.79Å; N613-I645 PolarHBondContact N-O 3.23Å; I645-M647 HydrophobicContact CG2-SD 3.99Å
646I96.3Very high91.9Very high0 Ų048.6 Ų48.60%025%0.246CC..EExtended strand (participates in β ladder)trans-118121175.4-59.5176.3000107.7V588 F589 I590 V591 N613 Y615 I633 Y644 F665V588-I646 HydrophobicContact CG1-CD1 4.24Å; F589-I646 PolarHBondContact O-N 2.91Å; I590-I646 CarbonylContact C-O 3.54Å; I590-I646 WeakPolarHBondContact CA-O 3.22Å; V591-I646 PolarHBondContact N-O 3.43Å; N613-I646 HydrophobicContact CB-CG1 4.44Å; N613-I646 WeakPolarHBondContact O-CA 3.46Å; Y615-I646 HydrophobicContact CD2-CG2 3.56Å; Y615-I646 HydrophobicContact CE2-CG2 3.55Å; I633-I646 HydrophobicContact CD1-CD1 4.2Å; Y644-I646 HydrophobicContact CD1-CD1 4.12Å; Y644-I646 HydrophobicContact CD1-CG1 3.71Å; Y644-I646 HydrophobicContact CE1-CD1 3.95Å; Y644-I646 HydrophobicContact CE1-CG1 3.59Å; I646-F665 HydrophobicContact CD1-CD2 4.18Å; I646-F665 HydrophobicContact CD1-CE2 3.37Å; I646-F665 HydrophobicContact CD1-CZ 3.99Å
647M97.7Very high92.4Very high0 Ų049.9 Ų49.90%026%0.257CS..EExtended strand (participates in β ladder)trans-82144168.6-53.5-52.7-58.100109.5I570 I574 V591 T593 A602 A606 A611 N613 A614 Y615 I645I570-M647 HydrophobicContact CG2-CE 4.12Å; I574-M647 HydrophobicContact CD1-CE 3.63Å; I574-M647 HydrophobicContact CD1-SD 3.52Å; I574-M647 VanDerWaalsContact CD1-SD 3.52Å; I574-M647 HydrophobicContact CG1-CE 4.38Å; I574-M647 HydrophobicContact CG1-SD 4.28Å; V591-M647 HydrophobicContact CB-CE 3.76Å; V591-M647 HydrophobicContact CB-SD 3.84Å; V591-M647 HydrophobicContact CG1-CE 3.64Å; V591-M647 HydrophobicContact CG1-SD 4.27Å; V591-M647 HydrophobicContact CG2-SD 4.4Å; V591-M647 CarbonylContact O-C 3.23Å; V591-M647 WeakPolarHBondContact O-CA 3.49Å; T593-M647 HydrophobicContact CG2-CE 3.41Å; T593-M647 VanDerWaalsContact CG2-CE 3.41Å; A602-M647 HydrophobicContact CB-CB 4.32Å; A606-M647 HydrophobicContact CB-CB 4.29Å; A606-M647 HydrophobicContact CB-CG 3.6Å; A611-M647 HydrophobicContact CB-CG 3.85Å; A611-M647 HydrophobicContact CB-SD 4.2Å; N613-M647 PolarHBondContact O-N 3.42Å; A614-M647 CarbonylContact C-O 3.58Å; A614-M647 WeakPolarHBondContact CA-O 3.39Å; A614-M647 HydrophobicContact CB-CB 3.87Å; Y615-M647 PolarHBondContact N-O 3.13Å; I645-M647 HydrophobicContact CG2-SD 3.99Å
648R97.9Very high92.8Very high7 Ų749.9 Ų49.93%0.02626%0.257CS..EExtended strand (participates in β ladder)trans-134.2125.9172171.9173.2172.1-66-12.3109.2I590 V591 E592 T593 Y615 E650 A652 N653 Y656 T658I590-R648 HydrophobicContact CG2-CB 4.35Å; V591-R648 PolarHBondContact O-N 3.34Å; E592-R648 CarbonylContact C-O 3.48Å; E592-R648 VanDerWaalsContact CA-O 3.27Å; E592-R648 WeakPolarHBondContact CA-O 3.38Å; E592-R648 IonicContact OE2-CZ 3.38Å; E592-R648 IonicContact OE2-NH1 3.72Å; E592-R648 PolarHBondContact OE2-NH1 3Å; T593-R648 PolarHBondContact N-O 2.91Å; Y615-R648 WeakPolarHBondContact O-CA 3.49Å; R648-E650 PolarHBondContact NH1-O 2.95Å; R648-E650 PolarHBondContact NH2-O 3.17Å; R648-A652 HydrophobicContact CG-CB 4.22Å; R648-N653 PolarHBondContact NH2-O 2.94Å; R648-Y656 PolarHBondContact NE-O 3.48Å; R648-Y656 PolarHBondContact NH2-O 3.29Å; R648-T658 WeakPolarHBondContact CD-OG1 3.29Å; R648-T658 PolarHBondContact NH1-OG1 3.44Å
649C98Very high93.3Very high0 Ų046.5 Ų46.50%024%0.244CC..EExtended strand (participates in β ladder)trans-69.5136.7166.2-174.70000109.6G596 C598 A602 Y615 I616 R651 A652G596-C649 PolarHBondContact O-SG 3.16Å; C598-C649 PolarHBondContact O-SG 3.29Å; C598-C649 VanDerWaalsContact O-SG 3.36Å; A602-C649 HydrophobicContact CB-CB 4.07Å; Y615-C649 PolarHBondContact O-N 3.05Å; I616-C649 HydrophobicContact CG2-CB 4.49Å; C649-R651 PolarHBondContact O-N 3.01Å; C649-R651 VanDerWaalsContact O-N 3.13Å; C649-A652 HydrophobicContact CB-CB 4.22Å; C649-A652 WeakPolarHBondContact O-CB 3.43Å; C649-A652 PolarHBondContact O-N 2.84Å
650E96.5Very high94Very high61 Ų6145.6 Ų45.629%0.28523%0.229SC..THydrogen-bonded Turntrans-51.3-37.8-175.358.9-177.9170.300114.1E592 T593 G595 G596 R648E592-E650 HydrophobicContact CG-CB 4.2Å; T593-E650 WeakPolarHBondContact O-CB 3.31Å; T593-E650 PolarHBondContact O-N 3.34Å; G595-E650 PolarHBondContact N-OE1 2.96Å; G595-E650 VanDerWaalsContact N-OE1 3.11Å; G596-E650 WeakPolarHBondContact CA-OE1 3.35Å; G596-E650 PolarHBondContact N-OE1 3.12Å; R648-E650 PolarHBondContact NH1-O 2.95Å; R648-E650 PolarHBondContact NH2-O 3.17Å
651R96.8Very high94.8Very high115 Ų11543.5 Ų43.543%0.43421%0.207SC..THydrogen-bonded Turntrans-105.626175.3-55.8-69.8-175.3155.3-2113.8G596 Y597 C649 N653G596-R651 VanDerWaalsContact O-CB 3.23Å; G596-R651 WeakPolarHBondContact O-CB 3.43Å; G596-R651 PolarHBondContact O-N 2.94Å; Y597-R651 HydrophobicContact CD1-CB 3.55Å; Y597-R651 HydrophobicContact CD1-CG 4.38Å; Y597-R651 HydrophobicContact CD2-CB 4.46Å; Y597-R651 HydrophobicContact CE1-CB 3.65Å; Y597-R651 HydrophobicContact CE1-CG 4.24Å; Y597-R651 HydrophobicContact CE2-CG 4.39Å; Y597-R651 HydrophobicContact CG-CB 3.99Å; C649-R651 PolarHBondContact O-N 3.01Å; C649-R651 VanDerWaalsContact O-N 3.13Å; R651-N653 PolarHBondContact O-N 2.8Å
652A97Very high95.5Very high6 Ų643.4 Ų43.45%0.0521%0.205CC..SBendtrans-54.9-39.417600000112.4F621 R648 C649F621-A652 HydrophobicContact CE1-CB 4.02Å; F621-A652 HydrophobicContact CZ-CB 4.29Å; R648-A652 HydrophobicContact CG-CB 4.22Å; C649-A652 HydrophobicContact CB-CB 4.22Å; C649-A652 WeakPolarHBondContact O-CB 3.43Å; C649-A652 PolarHBondContact O-N 2.84Å
653N96.9Very high96.2Very high44 Ų4444.8 Ų44.824%0.23521%0.211CC..  trans-155.9142.3169-172-72.9000108.4F621 R648 R651 N655 Y656F621-N653 HydrophobicContact CE1-CB 4.1Å; F621-N653 HydrophobicContact CZ-CB 3.75Å; R648-N653 PolarHBondContact NH2-O 2.94Å; R651-N653 PolarHBondContact O-N 2.8Å; N653-N655 PolarHBondContact OD1-N 3.3Å; N653-Y656 HydrophobicContact CB-CD2 3.91Å; N653-Y656 HydrophobicContact CB-CG 4.24Å; N653-Y656 VanDerWaalsContact CG-CD2 3.4Å; N653-Y656 PolarHBondContact OD1-N 3.14Å
654E94.4Very high96.6Very high148 Ų14844.9 Ų44.969%0.69221%0.213SC*.SBendtrans-70.8-39.2-178.6-174.1169.3-156.600112.6
655N96.3Very high96.8Very high125 Ų12544.9 Ų44.967%0.66821%0.213SC*.SBendtrans-87.3-37.1-178.1-64.1-48.9000112.1N653 T657N653-N655 PolarHBondContact OD1-N 3.3Å; N655-T657 PolarHBondContact O-N 3.1Å
656Y96.2Very high96.9Very high58 Ų5847 Ų4723%0.22723%0.228CC..SBendtrans-85.368.8178.5-45.4-36.5000110.6F621 V623 M626 R648 N653 F660F621-Y656 HydrophobicContact CD2-CD2 4.06Å; F621-Y656 AromaticContact CE2-CD2 3.66Å; F621-Y656 HydrophobicContact CE2-CD2 3.66Å; F621-Y656 HydrophobicContact CE2-CG 4.21Å; F621-Y656 HydrophobicContact CZ-CD2 4.21Å; F621-Y656 WeakPolarHBondContact O-CE2 3.25Å; V623-Y656 HydrophobicContact CG2-CE1 4.07Å; M626-Y656 HydrophobicContact CE-CD1 4Å; M626-Y656 HydrophobicContact CE-CD2 3.66Å; M626-Y656 HydrophobicContact CE-CE1 4.4Å; M626-Y656 HydrophobicContact CE-CE2 4.08Å; M626-Y656 HydrophobicContact CE-CG 3.62Å; R648-Y656 PolarHBondContact NE-O 3.48Å; R648-Y656 PolarHBondContact NH2-O 3.29Å; N653-Y656 HydrophobicContact CB-CD2 3.91Å; N653-Y656 HydrophobicContact CB-CG 4.24Å; N653-Y656 VanDerWaalsContact CG-CD2 3.4Å; N653-Y656 PolarHBondContact OD1-N 3.14Å; Y656-F660 AromaticContact CD1-CD1 4Å; Y656-F660 HydrophobicContact CD1-CD1 4Å; Y656-F660 AromaticContact CD1-CE1 3.78Å; Y656-F660 HydrophobicContact CD1-CE1 3.78Å; Y656-F660 HydrophobicContact CD1-CZ 4.45Å; Y656-F660 HydrophobicContact CE1-CE1 4.4Å; Y656-F660 HydrophobicContact CG-CD1 4.5Å; Y656-F660 HydrophobicContact CG-CE1 4.49Å
657T96.6Very high96.9Very high58 Ų5852.6 Ų52.636%0.35625%0.254SS..  trans-65.7159177.367.30000111.5N655 Q659 F660 I661N655-T657 PolarHBondContact O-N 3.1Å; T657-Q659 PolarHBondContact O-N 3.44Å; T657-Q659 VanDerWaalsContact O-N 3.15Å; T657-F660 WeakPolarHBondContact O-CB 3.33Å; T657-F660 PolarHBondContact O-N 2.98Å; T657-F660 WeakPolarHBondContact OG1-CB 3.27Å; T657-F660 PolarHBondContact OG1-N 3.16Å; T657-F660 VanDerWaalsContact OG1-N 3.08Å; T657-I661 WeakPolarHBondContact O-CG1 3.34Å; T657-I661 PolarHBondContact O-N 3.05Å
658T97.4Very high96.8Very high3 Ų357.2 Ų57.22%0.01828%0.276CS..Hα-helixtrans-53.2-36.5173.5-65.50000112I590 E592 R648 M662 I677I590-T658 HydrophobicContact CG2-CG2 3.97Å; E592-T658 VanDerWaalsContact OE2-CB 3.3Å; E592-T658 WeakPolarHBondContact OE2-CB 3.34Å; E592-T658 PolarHBondContact OE2-OG1 2.91Å; R648-T658 WeakPolarHBondContact CD-OG1 3.29Å; R648-T658 PolarHBondContact NH1-OG1 3.44Å; T658-M662 WeakPolarHBondContact O-CB 3.4Å; T658-M662 PolarHBondContact O-N 3.22Å; T658-I677 HydrophobicContact CG2-CB 3.7Å; T658-I677 HydrophobicContact CG2-CD1 4.39Å; T658-I677 HydrophobicContact CG2-CG2 3.47Å; T658-I677 VanDerWaalsContact CG2-CG2 3.47Å
659Q97.2Very high96.6Very high83 Ų8356.9 Ų56.939%0.38827%0.274SS..Hα-helixtrans-67.4-45.2176.1-175.363.815.600112.2T657 M662 Q663T657-Q659 PolarHBondContact O-N 3.44Å; T657-Q659 VanDerWaalsContact O-N 3.15Å; Q659-M662 VanDerWaalsContact NE2-CE 3.25Å; Q659-M662 WeakPolarHBondContact O-CB 3.35Å; Q659-M662 PolarHBondContact O-N 3.09Å; Q659-Q663 WeakPolarHBondContact O-CG 3.45Å; Q659-Q663 PolarHBondContact O-N 2.81Å
660F97.5Very high96.3Very high68 Ų6863.7 Ų63.730%0.29830%0.304SS..Hα-helixtrans-59.8-48.8176.7174.1-94.1000111.3V623 M626 Y656 T657 M662 Q663 L664V623-F660 HydrophobicContact CG2-CZ 4.45Å; M626-F660 HydrophobicContact CE-CE1 4.09Å; M626-F660 HydrophobicContact SD-CE1 4.44Å; Y656-F660 AromaticContact CD1-CD1 4Å; Y656-F660 HydrophobicContact CD1-CD1 4Å; Y656-F660 AromaticContact CD1-CE1 3.78Å; Y656-F660 HydrophobicContact CD1-CE1 3.78Å; Y656-F660 HydrophobicContact CD1-CZ 4.45Å; Y656-F660 HydrophobicContact CE1-CE1 4.4Å; Y656-F660 HydrophobicContact CG-CD1 4.5Å; Y656-F660 HydrophobicContact CG-CE1 4.49Å; T657-F660 WeakPolarHBondContact O-CB 3.33Å; T657-F660 PolarHBondContact O-N 2.98Å; T657-F660 WeakPolarHBondContact OG1-CB 3.27Å; T657-F660 PolarHBondContact OG1-N 3.16Å; T657-F660 VanDerWaalsContact OG1-N 3.08Å; F660-M662 VanDerWaalsContact C-N 3.27Å; F660-M662 PolarHBondContact O-N 2.94Å; F660-Q663 PolarHBondContact O-N 2.97Å; F660-Q663 VanDerWaalsContact O-N 3.13Å; F660-L664 HydrophobicContact CE1-CD2 4.24Å; F660-L664 PolarHBondContact O-N 3.49Å
661I97.4Very high95.9Very high0 Ų064.3 Ų64.30%033%0.327CS..Hα-helixtrans-60.8-40.8179.4-57.5178000110.2I590 Y615 F621 M626 T657 Q663 L664 F665I590-I661 HydrophobicContact CD1-CB 3.91Å; I590-I661 HydrophobicContact CD1-CG2 3.5Å; I590-I661 HydrophobicContact CG1-CG2 4.37Å; Y615-I661 HydrophobicContact CD2-CD1 3.97Å; Y615-I661 HydrophobicContact CE2-CD1 4.14Å; Y615-I661 HydrophobicContact CE2-CG2 4.37Å; F621-I661 HydrophobicContact CE2-CD1 4.43Å; M626-I661 HydrophobicContact SD-CD1 4.32Å; M626-I661 HydrophobicContact SD-CG1 3.79Å; M626-I661 HydrophobicContact SD-CG2 4.34Å; T657-I661 WeakPolarHBondContact O-CG1 3.34Å; T657-I661 PolarHBondContact O-N 3.05Å; I661-Q663 PolarHBondContact O-N 3.04Å; I661-L664 PolarHBondContact O-N 3.47Å; I661-F665 HydrophobicContact CG2-CD1 3.68Å; I661-F665 HydrophobicContact CG2-CE1 3.58Å; I661-F665 HydrophobicContact CG2-CG 4.32Å; I661-F665 HydrophobicContact CG2-CZ 4.16Å; I661-F665 VanDerWaalsContact O-CB 3.3Å; I661-F665 WeakPolarHBondContact O-CB 3.43Å; I661-F665 WeakPolarHBondContact O-CD1 3.29Å; I661-F665 WeakPolarHBondContact O-CG 3.32Å; I661-F665 PolarHBondContact O-N 2.88Å
662M97.2Very high95.7Very high33 Ų3361.2 Ų61.216%0.16332%0.319CS..Hα-helixtrans-59.5-46.1175.3-175.6-167.268.600112.3I590 T658 Q659 F660 S666 T675 I677I590-M662 HydrophobicContact CD1-CB 4.14Å; T658-M662 WeakPolarHBondContact O-CB 3.4Å; T658-M662 PolarHBondContact O-N 3.22Å; Q659-M662 VanDerWaalsContact NE2-CE 3.25Å; Q659-M662 WeakPolarHBondContact O-CB 3.35Å; Q659-M662 PolarHBondContact O-N 3.09Å; F660-M662 VanDerWaalsContact C-N 3.27Å; F660-M662 PolarHBondContact O-N 2.94Å; M662-S666 VanDerWaalsContact O-CB 3.24Å; M662-S666 WeakPolarHBondContact O-CB 3.4Å; M662-S666 PolarHBondContact O-N 3.32Å; M662-S666 PolarHBondContact O-OG 3.25Å; M662-T675 HydrophobicContact CB-CG2 4.46Å; M662-T675 HydrophobicContact CG-CG2 4.05Å; M662-I677 HydrophobicContact CB-CG2 3.52Å; M662-I677 HydrophobicContact CG-CG2 3.77Å; M662-I677 HydrophobicContact SD-CB 4.45Å; M662-I677 HydrophobicContact SD-CD1 4.37Å; M662-I677 HydrophobicContact SD-CG1 4.09Å; M662-I677 HydrophobicContact SD-CG2 3.68Å
663Q97.6Very high95.5Very high108 Ų10861.7 Ų61.751%0.50532%0.32SS..Hα-helixtrans-63.6-49-179.9-72.9171.1-26.200110.8Q659 F660 I661 F665 S666 E667Q659-Q663 WeakPolarHBondContact O-CG 3.45Å; Q659-Q663 PolarHBondContact O-N 2.81Å; F660-Q663 PolarHBondContact O-N 2.97Å; F660-Q663 VanDerWaalsContact O-N 3.13Å; I661-Q663 PolarHBondContact O-N 3.04Å; Q663-F665 PolarHBondContact O-N 3.23Å; Q663-S666 PolarHBondContact O-N 2.91Å; Q663-E667 PolarHBondContact O-N 3.5Å
664L97.1Very high95.4Very high26 Ų2661.3 Ų61.314%0.13632%0.321CS..Hα-helixtrans-56.2-50.9176.4178.966.1000111.3V623 M626 F660 I661 S666 E667 E668V623-L664 HydrophobicContact CG1-CD2 4.32Å; M626-L664 HydrophobicContact CB-CD2 3.76Å; M626-L664 HydrophobicContact CG-CD2 4.46Å; M626-L664 HydrophobicContact SD-CD2 3.89Å; F660-L664 HydrophobicContact CE1-CD2 4.24Å; F660-L664 PolarHBondContact O-N 3.49Å; I661-L664 PolarHBondContact O-N 3.47Å; L664-S666 VanDerWaalsContact C-N 3.29Å; L664-S666 PolarHBondContact O-N 2.92Å; L664-E667 PolarHBondContact O-N 2.82Å; L664-E668 HydrophobicContact CD1-CG 3.71Å; L664-E668 HydrophobicContact CG-CG 4.31Å; L664-E668 WeakPolarHBondContact O-CB 3.44Å; L664-E668 WeakPolarHBondContact O-CG 3.05Å; L664-E668 PolarHBondContact O-N 3.38Å
665F97.3Very high95.4Very high0 Ų054.3 Ų54.30%029%0.288CS..Hα-helixtrans-67.8-31-178-8246.7000112.1V588 M626 D629 V630 I633 I646 I661 Q663 G669 F673 T675V588-F665 HydrophobicContact CG1-CD2 4.35Å; M626-F665 HydrophobicContact CB-CE1 3.92Å; M626-F665 HydrophobicContact CG-CE1 4.16Å; D629-F665 HydrophobicContact CB-CZ 4.16Å; V630-F665 HydrophobicContact CG2-CB 4.34Å; V630-F665 HydrophobicContact CG2-CD1 3.76Å; V630-F665 HydrophobicContact CG2-CD2 3.89Å; V630-F665 HydrophobicContact CG2-CE1 3.93Å; V630-F665 HydrophobicContact CG2-CE2 4.02Å; V630-F665 HydrophobicContact CG2-CG 3.73Å; V630-F665 HydrophobicContact CG2-CZ 4.04Å; I633-F665 HydrophobicContact CD1-CD2 3.96Å; I633-F665 HydrophobicContact CD1-CE2 3.55Å; I646-F665 HydrophobicContact CD1-CD2 4.18Å; I646-F665 HydrophobicContact CD1-CE2 3.37Å; I646-F665 HydrophobicContact CD1-CZ 3.99Å; I661-F665 HydrophobicContact CG2-CD1 3.68Å; I661-F665 HydrophobicContact CG2-CE1 3.58Å; I661-F665 HydrophobicContact CG2-CG 4.32Å; I661-F665 HydrophobicContact CG2-CZ 4.16Å; I661-F665 VanDerWaalsContact O-CB 3.3Å; I661-F665 WeakPolarHBondContact O-CB 3.43Å; I661-F665 WeakPolarHBondContact O-CD1 3.29Å; I661-F665 WeakPolarHBondContact O-CG 3.32Å; I661-F665 PolarHBondContact O-N 2.88Å; Q663-F665 PolarHBondContact O-N 3.23Å; F665-G669 VanDerWaalsContact O-CA 3.28Å; F665-G669 WeakPolarHBondContact O-CA 3.24Å; F665-G669 PolarHBondContact O-N 3.28Å; F665-F673 HydrophobicContact CB-CE2 4.47Å; F665-F673 WeakPolarHBondContact O-CE2 3.39Å; F665-T675 HydrophobicContact CB-CG2 4.01Å
666S95.9Very high95.3Very high44 Ų4454.1 Ų54.131%0.30828%0.278SS..Hα-helixtrans-70.8-37.8177.3-60.70000111.9M662 Q663 L664 K670M662-S666 VanDerWaalsContact O-CB 3.24Å; M662-S666 WeakPolarHBondContact O-CB 3.4Å; M662-S666 PolarHBondContact O-N 3.32Å; M662-S666 PolarHBondContact O-OG 3.25Å; Q663-S666 PolarHBondContact O-N 2.91Å; L664-S666 VanDerWaalsContact C-N 3.29Å; L664-S666 PolarHBondContact O-N 2.92Å; S666-K670 PolarHBondContact O-N 3.32Å
667E96.8Very high95.4Very high118 Ų11853.8 Ų53.855%0.55128%0.28SS*.Hα-helixtrans-78.8-51.5179-16558.3-144.200111.3Q663 L664 G669 K670Q663-E667 PolarHBondContact O-N 3.5Å; L664-E667 PolarHBondContact O-N 2.82Å; E667-G669 VanDerWaalsContact C-N 3.27Å; E667-G669 PolarHBondContact O-N 2.83Å; E667-K670 WeakPolarHBondContact O-CB 3.47Å; E667-K670 PolarHBondContact O-N 3.49Å; E667-K670 IonicContact OE1-NZ 2.9Å; E667-K670 PolarHBondContact OE1-NZ 2.85Å
668E95.5Very high95.4Very high96 Ų9653.5 Ų53.545%0.44928%0.276SS..Hα-helixtrans-68.4-27.2-179.7-62.3-70.9141.100112.3V630 L664V630-E668 HydrophobicContact CB-CB 4.47Å; V630-E668 HydrophobicContact CG1-CB 3.86Å; V630-E668 HydrophobicContact CG2-CB 4.26Å; L664-E668 HydrophobicContact CD1-CG 3.71Å; L664-E668 HydrophobicContact CG-CG 4.31Å; L664-E668 WeakPolarHBondContact O-CB 3.44Å; L664-E668 WeakPolarHBondContact O-CG 3.05Å; L664-E668 PolarHBondContact O-N 3.38Å
669G93.4Very high95.4Very high0 Ų058.2 Ų58.20%030%0.3CS..THydrogen-bonded Turntrans-88.4-1177.700000114.8F665 E667 G671 N672 F673F665-G669 VanDerWaalsContact O-CA 3.28Å; F665-G669 WeakPolarHBondContact O-CA 3.24Å; F665-G669 PolarHBondContact O-N 3.28Å; E667-G669 VanDerWaalsContact C-N 3.27Å; E667-G669 PolarHBondContact O-N 2.83Å; G669-G671 PolarHBondContact O-N 2.97Å; G669-N672 WeakPolarHBondContact O-CA 3.37Å; G669-N672 WeakPolarHBondContact O-CB 3.38Å; G669-N672 PolarHBondContact O-N 3.03Å; G669-F673 PolarHBondContact O-N 3.4Å; G669-F673 VanDerWaalsContact O-N 3.15Å
670K91.2Very high95.4Very high143 Ų14355.3 Ų55.362%0.62229%0.287SS*.THydrogen-bonded Turntrans-54.3133.5-172.2-167.1173-174.1171.90111.8S666 E667 N672S666-K670 PolarHBondContact O-N 3.32Å; E667-K670 WeakPolarHBondContact O-CB 3.47Å; E667-K670 PolarHBondContact O-N 3.49Å; E667-K670 IonicContact OE1-NZ 2.9Å; E667-K670 PolarHBondContact OE1-NZ 2.85Å; K670-N672 PolarHBondContact O-N 3.38Å
671G88.9Confident95.3Very high75 Ų7553 Ų5377%0.77328%0.283SS*.THydrogen-bonded Turntrans80.1-17.5-174.500000115.3G669G669-G671 PolarHBondContact O-N 2.97Å
672N92.2Very high95.2Very high50 Ų5059.4 Ų59.427%0.26731%0.313SS..THydrogen-bonded Turntrans-98.6-44177.4-63.9-62.6000112.5R586 A634 G669 K670R586-N672 VanDerWaalsContact CD-O 3.28Å; R586-N672 WeakPolarHBondContact CD-O 3.4Å; A634-N672 HydrophobicContact CB-CB 4.11Å; G669-N672 WeakPolarHBondContact O-CA 3.37Å; G669-N672 WeakPolarHBondContact O-CB 3.38Å; G669-N672 PolarHBondContact O-N 3.03Å; K670-N672 PolarHBondContact O-N 3.38Å
673F93.3Very high95.1Very high16 Ų1660.4 Ų60.47%0.0732%0.323CS..  trans-155.5167.2-178.956.1-100.7000112.2R586 V588 V630 I633 A634 F665 G669R586-F673 HydrophobicContact CB-CB 4.28Å; R586-F673 WeakPolarHBondContact O-CA 3.28Å; R586-F673 WeakPolarHBondContact O-CB 3.16Å; V588-F673 HydrophobicContact CB-CD2 4.23Å; V588-F673 HydrophobicContact CB-CE2 4.43Å; V588-F673 HydrophobicContact CG2-CB 4.29Å; V588-F673 HydrophobicContact CG2-CD1 4.45Å; V588-F673 HydrophobicContact CG2-CD2 3.3Å; V588-F673 HydrophobicContact CG2-CE2 3.58Å; V588-F673 HydrophobicContact CG2-CG 3.78Å; V588-F673 HydrophobicContact CG2-CZ 4.25Å; V630-F673 HydrophobicContact CB-CZ 4.48Å; V630-F673 HydrophobicContact CG1-CE1 4.3Å; V630-F673 HydrophobicContact CG1-CZ 3.94Å; V630-F673 HydrophobicContact CG2-CZ 4.44Å; I633-F673 HydrophobicContact CB-CD1 4.39Å; I633-F673 HydrophobicContact CB-CE1 3.81Å; I633-F673 HydrophobicContact CB-CZ 4.19Å; I633-F673 HydrophobicContact CD1-CZ 4.48Å; I633-F673 HydrophobicContact CG2-CD1 3.53Å; I633-F673 HydrophobicContact CG2-CE1 3.41Å; I633-F673 VanDerWaalsContact CG2-CE1 3.41Å; I633-F673 HydrophobicContact CG2-CE2 4.41Å; I633-F673 HydrophobicContact CG2-CG 4.08Å; I633-F673 HydrophobicContact CG2-CZ 3.87Å; A634-F673 HydrophobicContact CB-CE1 4.29Å; F665-F673 HydrophobicContact CB-CE2 4.47Å; F665-F673 WeakPolarHBondContact O-CE2 3.39Å; G669-F673 PolarHBondContact O-N 3.4Å; G669-F673 VanDerWaalsContact O-N 3.15Å
674S93.5Very high95.1Very high36 Ų3655.3 Ų55.325%0.25230%0.299SS..EExtended strand (participates in β ladder)trans-107.1147170.760.20000111.1R586 R587 V588R586-S674 PolarHBondContact O-N 2.99Å; R587-S674 CarbonylContact C-O 3.6Å; R587-S674 WeakPolarHBondContact CA-O 3.39Å; R587-S674 PolarHBondContact NE-OG 3.33Å; V588-S674 PolarHBondContact N-O 3.24Å
675T95.1Very high95Very high1 Ų155.7 Ų55.71%0.00630%0.3CS..EExtended strand (participates in β ladder)trans-113.3139.1179.6-50.60000111.4V588 I590 M662 F665V588-T675 HydrophobicContact CB-CG2 4.23Å; V588-T675 HydrophobicContact CG1-CG2 4.27Å; V588-T675 CarbonylContact O-C 3.52Å; V588-T675 WeakPolarHBondContact O-CA 3.25Å; I590-T675 HydrophobicContact CD1-CG2 3.72Å; I590-T675 HydrophobicContact CG1-CG2 4.14Å; M662-T675 HydrophobicContact CB-CG2 4.46Å; M662-T675 HydrophobicContact CG-CG2 4.05Å; F665-T675 HydrophobicContact CB-CG2 4.01Å
676R95Very high94.6Very high120 Ų12056.9 Ų56.945%0.45331%0.312SS..EExtended strand (participates in β ladder)trans-134.5151.4175.8-68.2-64.8178.7-94.25.9110.5V588 F589 I590V588-R676 PolarHBondContact O-N 3.41Å; F589-R676 CarbonylContact C-O 3.56Å; F589-R676 WeakPolarHBondContact CA-O 3.35Å; F589-R676 HydrophobicContact CD1-CB 3.83Å; F589-R676 HydrophobicContact CE1-CB 3.89Å; F589-R676 HydrophobicContact CE1-CG 4.46Å; I590-R676 PolarHBondContact N-O 3.33Å
677I96.6Very high94.3Very high52 Ų5257.1 Ų57.127%0.26732%0.322SS..EExtended strand (participates in β ladder)trans-108.9147.717761.1172000110.5I590 T658 M662I590-I677 HydrophobicContact CB-CG2 4.27Å; I590-I677 HydrophobicContact CD1-CG2 4.45Å; I590-I677 CarbonylContact O-C 3.6Å; I590-I677 VanDerWaalsContact O-CA 3.31Å; I590-I677 WeakPolarHBondContact O-CA 3.22Å; T658-I677 HydrophobicContact CG2-CB 3.7Å; T658-I677 HydrophobicContact CG2-CD1 4.39Å; T658-I677 HydrophobicContact CG2-CG2 3.47Å; T658-I677 VanDerWaalsContact CG2-CG2 3.47Å; M662-I677 HydrophobicContact CB-CG2 3.52Å; M662-I677 HydrophobicContact CG-CG2 3.77Å; M662-I677 HydrophobicContact SD-CB 4.45Å; M662-I677 HydrophobicContact SD-CD1 4.37Å; M662-I677 HydrophobicContact SD-CG1 4.09Å; M662-I677 HydrophobicContact SD-CG2 3.68Å
678N96.8Very high94.1Very high51 Ų5155.3 Ų55.327%0.27332%0.321SS..EExtended strand (participates in β ladder)trans-135.1112.5168-71.8-96.7000108.2I577 F589 I590 V591 E592I577-N678 HydrophobicContact CD1-CB 3.82Å; F589-N678 WeakPolarHBondContact CD1-ND2 3.35Å; I590-N678 PolarHBondContact O-N 2.91Å; V591-N678 CarbonylContact C-O 3.57Å; V591-N678 WeakPolarHBondContact CA-O 3.29Å; V591-N678 HydrophobicContact CG2-CB 4.48Å; E592-N678 PolarHBondContact N-O 3.28Å
679I97.3Very high94.2Very high103 Ų10350.9 Ų50.953%0.52830%0.301SS..EExtended strand (participates in β ladder)trans-94.6106.7173.1-57.9174.2000106.7E592 G681E592-I679 HydrophobicContact CB-CG1 4.19Å; E592-I679 HydrophobicContact CB-CG2 4.47Å; I679-G681 VanDerWaalsContact C-N 3.28Å; I679-G681 PolarHBondContact O-N 3.46Å
680L97Very high94.4Very high21 Ų2151.4 Ų51.411%0.1130%0.304CS..  trans-68.3-32.6-174-56.3-175.6000111.6I570 L573 I577 V591 E592 S683 Q684I570-L680 HydrophobicContact CB-CD1 4.22Å; I570-L680 HydrophobicContact CG1-CD1 3.95Å; I570-L680 HydrophobicContact CG2-CD1 3.82Å; L573-L680 HydrophobicContact CB-CD2 4.02Å; L573-L680 HydrophobicContact CD1-CB 4.33Å; L573-L680 HydrophobicContact CD1-CD1 4.32Å; L573-L680 HydrophobicContact CD1-CD2 3.99Å; L573-L680 HydrophobicContact CD1-CG 4.44Å; I577-L680 HydrophobicContact CD1-CD2 4.49Å; V591-L680 HydrophobicContact CG1-CD1 3.76Å; V591-L680 HydrophobicContact CG1-CD2 3.81Å; V591-L680 HydrophobicContact CG1-CG 3.73Å; E592-L680 PolarHBondContact O-N 3.41Å; L680-S683 PolarHBondContact O-OG 3.3Å; L680-Q684 HydrophobicContact CB-CG 3.83Å; L680-Q684 HydrophobicContact CD1-CG 4.31Å
681G96Very high94.7Very high21 Ų2144.7 Ų44.722%0.21628%0.275CS..G310 helixtrans57.5-146.1177.300000112.9I679 S683 Q684I679-G681 VanDerWaalsContact C-N 3.28Å; I679-G681 PolarHBondContact O-N 3.46Å; G681-S683 PolarHBondContact O-N 3.25Å; G681-S683 VanDerWaalsContact O-N 3.1Å; G681-Q684 WeakPolarHBondContact O-CG 3.41Å; G681-Q684 PolarHBondContact O-N 3.35Å; G681-Q684 PolarHBondContact O-NE2 3.15Å
682H96.2Very high95Very high134 Ų13443.6 Ų43.662%0.6225%0.249SC*.G310 helixtrans-67.1-11-172.8-6884.9000114.9Q684 Q685H682-Q684 PolarHBondContact O-N 2.98Å; H682-Q685 WeakPolarHBondContact O-CB 3.41Å; H682-Q685 PolarHBondContact O-N 2.88Å
683S94.8Very high95.2Very high53 Ų5341.2 Ų41.237%0.37124%0.237SC..G310 helixtrans-56.7-24.3172.465.20000112.7L573 L680 G681 Q685 G686L573-S683 VanDerWaalsContact CD1-OG 3.28Å; L573-S683 WeakPolarHBondContact CD1-OG 3.47Å; L680-S683 PolarHBondContact O-OG 3.3Å; G681-S683 PolarHBondContact O-N 3.25Å; G681-S683 VanDerWaalsContact O-N 3.1Å; S683-Q685 PolarHBondContact O-N 3.23Å; S683-G686 PolarHBondContact O-N 3.25Å
684Q97.1Very high95.4Very high1 Ų140.6 Ų40.61%0.00523%0.234CC..G310 helixtrans-67-16.1175.9-63.2172.886.500113.8I550 A566 I570 T593 M594 L680 G681 H682 G686I550-Q684 HydrophobicContact CD1-CB 4.33Å; A566-Q684 WeakPolarHBondContact CA-O 3.44Å; A566-Q684 WeakPolarHBondContact CB-O 3.37Å; I570-Q684 HydrophobicContact CD1-CG 4.24Å; I570-Q684 HydrophobicContact CG1-CB 4.45Å; I570-Q684 HydrophobicContact CG1-CG 3.74Å; T593-Q684 VanDerWaalsContact CA-OE1 3.25Å; M594-Q684 VanDerWaalsContact CG-NE2 3.3Å; M594-Q684 VanDerWaalsContact N-NE2 3.1Å; L680-Q684 HydrophobicContact CB-CG 3.83Å; L680-Q684 HydrophobicContact CD1-CG 4.31Å; G681-Q684 WeakPolarHBondContact O-CG 3.41Å; G681-Q684 PolarHBondContact O-N 3.35Å; G681-Q684 PolarHBondContact O-NE2 3.15Å; H682-Q684 PolarHBondContact O-N 2.98Å; Q684-G686 PolarHBondContact O-N 3.28Å
685Q95.4Very high95.5Very high34 Ų3439.5 Ų39.516%0.15923%0.225CC..G310 helixtrans-73.5-12.8175.7-70.3177.1-17.500113C434 I550 H682 S683C434-Q685 PolarHBondContact SG-O 3.14Å; I550-Q685 HydrophobicContact CD1-CG 4.22Å; H682-Q685 WeakPolarHBondContact O-CB 3.41Å; H682-Q685 PolarHBondContact O-N 2.88Å; S683-Q685 PolarHBondContact O-N 3.23Å
686G89.7Confident95.4Very high25 Ų2539.9 Ų39.926%0.25823%0.227SC..  trans78.5162.6-178.500000113.5S683 Q684S683-G686 PolarHBondContact O-N 3.25Å; Q684-G686 PolarHBondContact O-N 3.28Å
687G89Confident95.5Very high49 Ų4934.2 Ų34.251%0.50521%0.206SC..SBendtrans-101.4-68.7168.700000110.1G484G484-G687 WeakPolarHBondContact CA-O 3.31Å; G484-G687 PolarHBondContact N-O 3.28Å
688C92.6Very high95.4Very high81 Ų8131.7 Ų31.755%0.54719%0.193SC..SBendtrans-97132.3174.6-57.20000109.7
689P96.7Very high95.2Very high3 Ų331.6 Ų31.62%0.01919%0.188CC..PPolyproline II helixtrans-66.5143.9177.325.5-26.9000110.4C434 S481 M482 R694C434-P689 HydrophobicContact CB-CB 3.7Å; S481-P689 WeakPolarHBondContact O-CG 3.38Å; M482-P689 WeakPolarHBondContact O-CD 3.38Å; P689-R694 HydrophobicContact CB-CG 3.87Å; P689-R694 HydrophobicContact CG-CG 3.68Å; P689-R694 PolarHBondContact O-NE 3.45Å; P689-R694 PolarHBondContact O-NH2 3.08Å; P689-R694 VanDerWaalsContact O-NH2 3.16Å
690T97.8Very high95Very high10 Ų1026.9 Ų26.96%0.06117%0.165CC..PPolyproline II helixtrans-65.4157175.8610000111.3H199 D564 S565 N568 F692 D693 R694H199-T690 VanDerWaalsContact CE1-CG2 3.41Å; H199-T690 WeakPolarHBondContact CE1-CG2 3.5Å; D564-T690 WeakPolarHBondContact OD2-CB 3.47Å; D564-T690 WeakPolarHBondContact OD2-CG2 3.23Å; D564-T690 PolarHBondContact OD2-OG1 2.75Å; S565-T690 PolarHBondContact OG-N 2.93Å; S565-T690 VanDerWaalsContact OG-N 3.12Å; S565-T690 PolarHBondContact OG-OG1 3.34Å; N568-T690 HydrophobicContact CB-CG2 4.19Å; T690-F692 PolarHBondContact O-N 2.91Å; T690-D693 PolarHBondContact O-N 3.22Å; T690-D693 PolarHBondContact OG1-N 2.97Å; T690-R694 WeakPolarHBondContact O-CG 3.32Å; T690-R694 PolarHBondContact O-N 3.35Å
691P97.1Very high95Very high3 Ų325.9 Ų25.92%0.01916%0.159CC..Hα-helixtrans-53.2-38.4173.8-1927.3000112.2L198 H199 I202 R694 N695L198-P691 HydrophobicContact CB-CB 3.87Å; L198-P691 HydrophobicContact CB-CG 3.97Å; L198-P691 WeakPolarHBondContact O-CG 3.22Å; H199-P691 HydrophobicContact CB-CG 4.39Å; H199-P691 VanDerWaalsContact CD2-CD 3.42Å; H199-P691 WeakPolarHBondContact CD2-CD 3.42Å; I202-P691 HydrophobicContact CB-CG 4.04Å; I202-P691 HydrophobicContact CG1-CB 3.9Å; I202-P691 HydrophobicContact CG1-CG 3.74Å; P691-R694 PolarHBondContact O-N 2.95Å; P691-N695 VanDerWaalsContact O-CB 3.29Å; P691-N695 WeakPolarHBondContact O-CB 3.44Å; P691-N695 PolarHBondContact O-N 3.41Å
692F95.7Very high94.9Very high52 Ų5225.1 Ų25.123%0.22815%0.151CC..Hα-helixtrans-60.3-54.6176.8-175.9-88.3000111.5I559 D564 T690 R694 N695 L696I559-F692 HydrophobicContact CD1-CE1 3.52Å; I559-F692 HydrophobicContact CD1-CZ 3.78Å; I559-F692 HydrophobicContact CG1-CE1 4.38Å; D564-F692 HydrophobicContact CB-CB 4.43Å; D564-F692 HydrophobicContact CB-CD1 3.71Å; D564-F692 HydrophobicContact CB-CE1 4.42Å; D564-F692 HydrophobicContact CB-CG 4.35Å; T690-F692 PolarHBondContact O-N 2.91Å; F692-R694 VanDerWaalsContact C-N 3.34Å; F692-R694 PolarHBondContact O-N 2.98Å; F692-N695 PolarHBondContact O-N 2.82Å; F692-L696 HydrophobicContact CE1-CB 4.37Å; F692-L696 HydrophobicContact CE1-CD2 3.73Å; F692-L696 HydrophobicContact CZ-CD2 4.3Å; F692-L696 VanDerWaalsContact O-CB 3.24Å; F692-L696 WeakPolarHBondContact O-CB 3.31Å; F692-L696 PolarHBondContact O-N 3.11Å
693D97.4Very high94.7Very high0 Ų020.3 Ų20.30%013%0.129CC..Hα-helixtrans-64.6-36.5-179.8-82.8-34.8000112.4G562 S565 T690 A697G562-D693 WeakPolarHBondContact CA-OD2 3.47Å; G562-D693 PolarHBondContact N-OD1 3.18Å; G562-D693 PolarHBondContact N-OD2 3.42Å; S565-D693 WeakPolarHBondContact CB-OD2 3.37Å; S565-D693 PolarHBondContact N-OD2 2.99Å; S565-D693 PolarHBondContact OG-OD2 3Å; T690-D693 PolarHBondContact O-N 3.22Å; T690-D693 PolarHBondContact OG1-N 2.97Å; D693-A697 WeakPolarHBondContact O-CB 3.32Å; D693-A697 PolarHBondContact O-N 3.03Å
694R96.7Very high94.8Very high2 Ų217.8 Ų17.81%0.00811%0.111CC..Hα-helixtrans-61.5-49.5173.8-68.4-172.8-152.8-165.60.2111.4D206 A238 S481 P689 T690 P691 F692 T698D206-R694 IonicContact OD1-CZ 3.93Å; D206-R694 IonicContact OD1-NH1 3.62Å; D206-R694 PolarHBondContact OD1-NH1 3.45Å; D206-R694 IonicContact OD1-NH2 3.17Å; D206-R694 IonicContact OD2-CZ 2.6Å; D206-R694 IonicContact OD2-NH1 3.24Å; D206-R694 PolarHBondContact OD2-NH1 2.87Å; D206-R694 IonicContact OD2-NH2 3.22Å; D206-R694 PolarHBondContact OD2-NH2 3.34Å; A238-R694 HydrophobicContact CB-CB 3.86Å; A238-R694 WeakPolarHBondContact O-CD 3.46Å; S481-R694 WeakPolarHBondContact O-CD 3.09Å; S481-R694 WeakPolarHBondContact O-CG 3.23Å; P689-R694 HydrophobicContact CB-CG 3.87Å; P689-R694 HydrophobicContact CG-CG 3.68Å; P689-R694 PolarHBondContact O-NE 3.45Å; P689-R694 PolarHBondContact O-NH2 3.08Å; P689-R694 VanDerWaalsContact O-NH2 3.16Å; T690-R694 WeakPolarHBondContact O-CG 3.32Å; T690-R694 PolarHBondContact O-N 3.35Å; P691-R694 PolarHBondContact O-N 2.95Å; F692-R694 VanDerWaalsContact C-N 3.34Å; F692-R694 PolarHBondContact O-N 2.98Å; R694-T698 VanDerWaalsContact O-CB 3.25Å; R694-T698 WeakPolarHBondContact O-CB 3.47Å; R694-T698 PolarHBondContact O-N 2.98Å; R694-T698 PolarHBondContact O-OG1 3.43Å
695N94.8Very high94.7Very high13 Ų1317.8 Ų17.87%0.0711%0.111CC..Hα-helixtrans-66.7-45.1-179-178.7-87.4000111.4V234 L237 N397 P691 F692 T698 R699V234-N695 HydrophobicContact CG1-CB 4.29Å; L237-N695 WeakPolarHBondContact CD1-ND2 3.1Å; N397-N695 PolarHBondContact OD1-ND2 3.39Å; N397-N695 PolarHBondContact OD1-OD1 2.81Å; P691-N695 VanDerWaalsContact O-CB 3.29Å; P691-N695 WeakPolarHBondContact O-CB 3.44Å; P691-N695 PolarHBondContact O-N 3.41Å; F692-N695 PolarHBondContact O-N 2.82Å; N695-T698 PolarHBondContact O-N 3.37Å; N695-R699 WeakPolarHBondContact O-CB 3.4Å; N695-R699 WeakPolarHBondContact O-CG 3.21Å; N695-R699 PolarHBondContact O-N 3.39Å; N695-R699 WeakPolarHBondContact OD1-CD 3.38Å
696L94.1Very high94.6Very high10 Ų1020 Ų205%0.05212%0.121CC..Hα-helixtrans-61.1-51.5179.6-178.563.1000111I559 I561 F692 T698 R699 M700 I735I559-L696 HydrophobicContact CG2-CD2 4.27Å; I561-L696 HydrophobicContact CG1-CB 4.43Å; I561-L696 HydrophobicContact CG1-CD2 3.77Å; I561-L696 HydrophobicContact CG1-CG 3.83Å; F692-L696 HydrophobicContact CE1-CB 4.37Å; F692-L696 HydrophobicContact CE1-CD2 3.73Å; F692-L696 HydrophobicContact CZ-CD2 4.3Å; F692-L696 VanDerWaalsContact O-CB 3.24Å; F692-L696 WeakPolarHBondContact O-CB 3.31Å; F692-L696 PolarHBondContact O-N 3.11Å; L696-T698 VanDerWaalsContact C-N 3.28Å; L696-T698 PolarHBondContact O-N 2.78Å; L696-R699 PolarHBondContact O-N 2.86Å; L696-M700 HydrophobicContact CD1-CG 3.84Å; L696-M700 HydrophobicContact CD1-SD 3.44Å; L696-M700 WeakPolarHBondContact CD1-SD 3.33Å; L696-M700 HydrophobicContact CD2-SD 4.37Å; L696-M700 HydrophobicContact CG-CG 4.36Å; L696-M700 HydrophobicContact CG-SD 3.76Å; L696-M700 WeakPolarHBondContact O-CB 3.35Å; L696-M700 WeakPolarHBondContact O-CG 3.44Å; L696-M700 PolarHBondContact O-N 2.9Å; L696-I735 HydrophobicContact CD1-CD1 3.6Å
697A96.9Very high94.9Very high0 Ų020 Ų200%012%0.116CC..Hα-helixtrans-56-45.6176.700000111.9G435 A438 A439 I561 D693 A701G435-A697 WeakPolarHBondContact O-CB 3.49Å; A438-A697 HydrophobicContact CB-CB 3.87Å; A439-A697 HydrophobicContact CB-CB 4.12Å; I561-A697 HydrophobicContact CD1-CB 3.99Å; I561-A697 HydrophobicContact CG1-CB 4.33Å; I561-A697 HydrophobicContact CG2-CB 3.9Å; D693-A697 WeakPolarHBondContact O-CB 3.32Å; D693-A697 PolarHBondContact O-N 3.03Å; A697-A701 WeakPolarHBondContact O-CB 3.32Å; A697-A701 PolarHBondContact O-N 3.18Å
698T94.6Very high95.3Very high0 Ų017.6 Ų17.60%09%0.092CC..Hα-helixtrans-61.3-49.5180-63.70000111.5T400 L404 S442 R694 N695 L696 A702T400-T698 HydrophobicContact CG2-CG2 4.3Å; L404-T698 HydrophobicContact CD1-CG2 3.18Å; S442-T698 WeakPolarHBondContact CB-O 3.49Å; S442-T698 PolarHBondContact OG-O 3.21Å; R694-T698 VanDerWaalsContact O-CB 3.25Å; R694-T698 WeakPolarHBondContact O-CB 3.47Å; R694-T698 PolarHBondContact O-N 2.98Å; R694-T698 PolarHBondContact O-OG1 3.43Å; N695-T698 PolarHBondContact O-N 3.37Å; L696-T698 VanDerWaalsContact C-N 3.28Å; L696-T698 PolarHBondContact O-N 2.78Å; T698-A702 WeakPolarHBondContact O-CB 3.33Å; T698-A702 PolarHBondContact O-N 3.09Å; T698-A702 VanDerWaalsContact O-N 3.08Å
699R91.9Very high95.4Very high48 Ų4813.8 Ų13.818%0.1817%0.066CC..Hα-helixtrans-67.6-43.2-178.7-73.6168.359.9-168.3-8113.1N397 T400 N695 L696 A702 Q703N397-R699 WeakPolarHBondContact OD1-CD 3.27Å; T400-R699 HydrophobicContact CG2-CG 4.34Å; N695-R699 WeakPolarHBondContact O-CB 3.4Å; N695-R699 WeakPolarHBondContact O-CG 3.21Å; N695-R699 PolarHBondContact O-N 3.39Å; N695-R699 WeakPolarHBondContact OD1-CD 3.38Å; L696-R699 PolarHBondContact O-N 2.86Å; R699-A702 PolarHBondContact O-N 2.86Å; R699-Q703 PolarHBondContact O-N 3.47Å; R699-Q703 VanDerWaalsContact O-N 3.14Å
700M94.5Very high95.3Very high5 Ų515.4 Ų15.43%0.0258%0.077CC..Hα-helixtrans-71-39-177.7-66.1-175.277.700110.8L546 I561 L696 A702 Q703 A704 L733 I735L546-M700 HydrophobicContact CD1-CB 3.47Å; L546-M700 VanDerWaalsContact CD1-CB 3.47Å; L546-M700 HydrophobicContact CD1-CE 3.65Å; L546-M700 HydrophobicContact CD1-CG 4.28Å; L546-M700 HydrophobicContact CD1-SD 3.9Å; L546-M700 HydrophobicContact CD2-CB 4.33Å; I561-M700 HydrophobicContact CD1-SD 4.31Å; L696-M700 HydrophobicContact CD1-CG 3.84Å; L696-M700 HydrophobicContact CD1-SD 3.44Å; L696-M700 WeakPolarHBondContact CD1-SD 3.33Å; L696-M700 HydrophobicContact CD2-SD 4.37Å; L696-M700 HydrophobicContact CG-CG 4.36Å; L696-M700 HydrophobicContact CG-SD 3.76Å; L696-M700 WeakPolarHBondContact O-CB 3.35Å; L696-M700 WeakPolarHBondContact O-CG 3.44Å; L696-M700 PolarHBondContact O-N 2.9Å; M700-A702 VanDerWaalsContact C-N 3.34Å; M700-A702 PolarHBondContact O-N 2.78Å; M700-Q703 PolarHBondContact O-N 2.85Å; M700-A704 WeakPolarHBondContact O-CB 3.46Å; M700-A704 PolarHBondContact O-N 2.92Å; M700-L733 HydrophobicContact CB-CD2 4.28Å; M700-L733 HydrophobicContact CE-CG 3.98Å; M700-L733 WeakPolarHBondContact CE-O 3.33Å; M700-L733 WeakPolarHBondContact O-CD2 3.38Å; M700-I735 HydrophobicContact CE-CG1 4.36Å; M700-I735 HydrophobicContact SD-CD1 4.39Å; M700-I735 HydrophobicContact SD-CG1 4.48Å
701A96.6Very high95.2Very high0 Ų016.8 Ų16.80%08%0.082CC..Hα-helixtrans-68.2-31.6175.200000113.3A439 F443 F515 L546 A697 A704 A705A439-A701 HydrophobicContact CB-CB 4.03Å; A439-A701 WeakPolarHBondContact O-CB 3.2Å; F443-A701 HydrophobicContact CB-CB 4.25Å; F515-A701 HydrophobicContact CE1-CB 4.19Å; F515-A701 HydrophobicContact CZ-CB 4.18Å; L546-A701 HydrophobicContact CD2-CB 4.27Å; A697-A701 WeakPolarHBondContact O-CB 3.32Å; A697-A701 PolarHBondContact O-N 3.18Å; A701-A704 PolarHBondContact O-N 3.2Å; A701-A705 PolarHBondContact O-N 3.09Å
702A92.8Very high95.2Very high4 Ų416.6 Ų16.63%0.0338%0.081CC..Hα-helixtrans-62.3-48.7170.700000111T400 S442 N446 T698 R699 M700 A704 A705 E706T400-A702 HydrophobicContact CG2-CB 4.36Å; S442-A702 PolarHBondContact OG-N 3.28Å; N446-A702 WeakPolarHBondContact ND2-CB 3.44Å; T698-A702 WeakPolarHBondContact O-CB 3.33Å; T698-A702 PolarHBondContact O-N 3.09Å; T698-A702 VanDerWaalsContact O-N 3.08Å; R699-A702 PolarHBondContact O-N 2.86Å; M700-A702 VanDerWaalsContact C-N 3.34Å; M700-A702 PolarHBondContact O-N 2.78Å; A702-A704 VanDerWaalsContact C-N 3.29Å; A702-A704 PolarHBondContact O-N 3.13Å; A702-A705 WeakPolarHBondContact O-CB 3.3Å; A702-A705 PolarHBondContact O-N 3.3Å; A702-E706 PolarHBondContact O-N 3.4Å; A702-E706 VanDerWaalsContact O-N 3.1Å
703Q93Very high95.2Very high34 Ų3419.5 Ų19.516%0.1599%0.091CC..Hα-helixtrans-62.2-36.1174.7-179.6-177.3-6.200112.2R699 M700 A705 E706 T707 L733 S740R699-Q703 PolarHBondContact O-N 3.47Å; R699-Q703 VanDerWaalsContact O-N 3.14Å; M700-Q703 PolarHBondContact O-N 2.85Å; Q703-A705 VanDerWaalsContact C-N 3.34Å; Q703-E706 PolarHBondContact O-N 2.75Å; Q703-T707 WeakPolarHBondContact O-CB 3.25Å; Q703-T707 PolarHBondContact O-N 2.73Å; Q703-T707 PolarHBondContact O-OG1 3.36Å; Q703-L733 HydrophobicContact CB-CD2 3.97Å; Q703-L733 HydrophobicContact CG-CD1 4.35Å; Q703-L733 HydrophobicContact CG-CD2 3.98Å; Q703-S740 VanDerWaalsContact OE1-CB 3.24Å; Q703-S740 PolarHBondContact OE1-OG 3.27Å
704A96.9Very high95Very high0 Ų024.8 Ų24.80%012%0.115CC..Hα-helixtrans-63.7-40176.300000111.9F515 V544 M700 A701 A702 T707 L708 L733F515-A704 HydrophobicContact CD2-CB 3.95Å; F515-A704 HydrophobicContact CE2-CB 3.35Å; F515-A704 HydrophobicContact CZ-CB 3.69Å; V544-A704 HydrophobicContact CG1-CB 3.82Å; M700-A704 WeakPolarHBondContact O-CB 3.46Å; M700-A704 PolarHBondContact O-N 2.92Å; A701-A704 PolarHBondContact O-N 3.2Å; A702-A704 VanDerWaalsContact C-N 3.29Å; A702-A704 PolarHBondContact O-N 3.13Å; A704-T707 PolarHBondContact O-N 2.97Å; A704-L708 PolarHBondContact O-N 2.82Å; A704-L733 HydrophobicContact CB-CD2 4.06Å
705A95.5Very high95Very high0 Ų025.1 Ų25.10%012%0.118CC..Hα-helixtrans-61.9-49.1173.700000111.5F443 N446 A701 A702 Q703 T707 L708 V709F443-A705 HydrophobicContact CD2-CB 3.74Å; F443-A705 HydrophobicContact CE2-CB 3.96Å; N446-A705 HydrophobicContact CB-CB 3.61Å; A701-A705 PolarHBondContact O-N 3.09Å; A702-A705 WeakPolarHBondContact O-CB 3.3Å; A702-A705 PolarHBondContact O-N 3.3Å; Q703-A705 VanDerWaalsContact C-N 3.34Å; A705-T707 VanDerWaalsContact C-N 3.29Å; A705-T707 PolarHBondContact O-N 2.98Å; A705-L708 PolarHBondContact O-N 3.45Å; A705-V709 VanDerWaalsContact O-CG2 3.3Å; A705-V709 WeakPolarHBondContact O-CG2 3.3Å; A705-V709 PolarHBondContact O-N 3.38Å
706E92.9Very high95Very high80 Ų8026.4 Ų26.437%0.37413%0.126SC..Hα-helixtrans-59.3-41176.3-68177.3176.900111.9L416 A702 Q703 V709 S710L416-E706 HydrophobicContact CD1-CB 4.31Å; L416-E706 HydrophobicContact CD1-CG 3.9Å; A702-E706 PolarHBondContact O-N 3.4Å; A702-E706 VanDerWaalsContact O-N 3.1Å; Q703-E706 PolarHBondContact O-N 2.75Å; E706-V709 PolarHBondContact O-N 3.04Å; E706-S710 WeakPolarHBondContact O-CB 3.21Å; E706-S710 PolarHBondContact O-N 3.15Å
707T95.5Very high95Very high25 Ų2529.2 Ų29.215%0.15314%0.139CC..Hα-helixtrans-63.1-47.6177.5-57.70000111.1V544 Q703 A704 A705 S710 K711V544-T707 HydrophobicContact CG2-CG2 4Å; Q703-T707 WeakPolarHBondContact O-CB 3.25Å; Q703-T707 PolarHBondContact O-N 2.73Å; Q703-T707 PolarHBondContact O-OG1 3.36Å; A704-T707 PolarHBondContact O-N 2.97Å; A705-T707 VanDerWaalsContact C-N 3.29Å; A705-T707 PolarHBondContact O-N 2.98Å; T707-S710 PolarHBondContact O-N 3.34Å; T707-K711 HydrophobicContact CG2-CG 4.41Å; T707-K711 WeakPolarHBondContact O-CB 3.44Å; T707-K711 WeakPolarHBondContact O-CG 3.19Å; T707-K711 PolarHBondContact O-N 2.76Å
708L97.3Very high94.7Very high0 Ų035.8 Ų35.80%018%0.182CC..Hα-helixtrans-62.8-42.7177.3-81.5178.4000111.7F424 F443 F515 P542 V544 A704 A705 K711 A712F424-L708 HydrophobicContact CE1-CB 4.44Å; F424-L708 HydrophobicContact CE2-CB 4.14Å; F424-L708 HydrophobicContact CZ-CB 4.07Å; F443-L708 HydrophobicContact CE2-CD1 3.69Å; F443-L708 HydrophobicContact CZ-CD1 3.82Å; F515-L708 HydrophobicContact CB-CD1 3.91Å; P542-L708 HydrophobicContact CB-CD2 3.68Å; P542-L708 WeakPolarHBondContact O-CD2 3.36Å; V544-L708 HydrophobicContact CB-CD2 4.43Å; V544-L708 HydrophobicContact CB-CG 4.26Å; V544-L708 HydrophobicContact CG2-CD2 3.76Å; V544-L708 HydrophobicContact CG2-CG 3.7Å; A704-L708 PolarHBondContact O-N 2.82Å; A705-L708 PolarHBondContact O-N 3.45Å; L708-K711 PolarHBondContact O-N 3.49Å; L708-A712 WeakPolarHBondContact O-CB 3.38Å; L708-A712 PolarHBondContact O-N 2.87Å
709V95.1Very high94.4Very high0 Ų041.4 Ų41.40%021%0.212CC..Hα-helixtrans-62-47176.6175.10000111.3L416 F424 H450 A705 E706 R713L416-V709 HydrophobicContact CB-CG1 3.8Å; F424-V709 HydrophobicContact CE2-CG2 3.7Å; F424-V709 HydrophobicContact CZ-CG2 4.19Å; H450-V709 HydrophobicContact CB-CG1 4.47Å; H450-V709 HydrophobicContact CB-CG2 4.04Å; A705-V709 VanDerWaalsContact O-CG2 3.3Å; A705-V709 WeakPolarHBondContact O-CG2 3.3Å; A705-V709 PolarHBondContact O-N 3.38Å; E706-V709 PolarHBondContact O-N 3.04Å; V709-R713 WeakPolarHBondContact O-CB 3.35Å; V709-R713 PolarHBondContact O-N 2.75Å
710S94.6Very high94.2Very high37 Ų3741.5 Ų41.526%0.25923%0.228SC..Hα-helixtrans-61.5-49.3178.8-165.10000111.2E706 T707 A712 R713 E714E706-S710 WeakPolarHBondContact O-CB 3.21Å; E706-S710 PolarHBondContact O-N 3.15Å; T707-S710 PolarHBondContact O-N 3.34Å; S710-A712 PolarHBondContact O-N 3.07Å; S710-R713 WeakPolarHBondContact O-CB 3.33Å; S710-R713 PolarHBondContact O-N 3.47Å; S710-E714 WeakPolarHBondContact O-CG 3.33Å; S710-E714 PolarHBondContact O-N 2.82Å; S710-E714 PolarHBondContact OG-OE1 2.86Å
711K96.5Very high94.1Very high39 Ų3942.7 Ų42.717%0.1724%0.237CC..Hα-helixtrans-67.6-36.4-178.4-70.1-66.9170.6-162.20112.7P542 T707 L708 E714 S715 D728P542-K711 HydrophobicContact CB-CB 3.84Å; P542-K711 HydrophobicContact CG-CB 3.84Å; T707-K711 HydrophobicContact CG2-CG 4.41Å; T707-K711 WeakPolarHBondContact O-CB 3.44Å; T707-K711 WeakPolarHBondContact O-CG 3.19Å; T707-K711 PolarHBondContact O-N 2.76Å; L708-K711 PolarHBondContact O-N 3.49Å; K711-E714 WeakPolarHBondContact CD-OE2 3.35Å; K711-E714 IonicContact NZ-OE2 3.58Å; K711-E714 PolarHBondContact NZ-OE2 3.43Å; K711-E714 PolarHBondContact O-N 3.01Å; K711-S715 VanDerWaalsContact O-CB 3.23Å; K711-S715 WeakPolarHBondContact O-CB 3.37Å; K711-S715 PolarHBondContact O-N 3.32Å; K711-S715 PolarHBondContact O-OG 2.77Å; K711-D728 IonicContact NZ-OD2 2.83Å; K711-D728 PolarHBondContact NZ-OD2 2.85Å
712A96.7Very high94Very high0 Ų043.2 Ų43.20%024%0.24CC..Hα-helixtrans-62.9-45.6173.600000110.6F422 F424 P542 L708 S710 E714 S715 V716 V722F422-A712 HydrophobicContact CD1-CB 3.88Å; F422-A712 HydrophobicContact CD2-CB 3.95Å; F422-A712 HydrophobicContact CE1-CB 3.89Å; F422-A712 HydrophobicContact CE2-CB 3.95Å; F422-A712 HydrophobicContact CG-CB 3.92Å; F422-A712 HydrophobicContact CZ-CB 3.93Å; F424-A712 HydrophobicContact CE1-CB 4Å; F424-A712 HydrophobicContact CZ-CB 4.03Å; P542-A712 HydrophobicContact CG-CB 4.41Å; L708-A712 WeakPolarHBondContact O-CB 3.38Å; L708-A712 PolarHBondContact O-N 2.87Å; S710-A712 PolarHBondContact O-N 3.07Å; A712-E714 PolarHBondContact O-N 2.9Å; A712-S715 CarbonylContact O-C 3.5Å; A712-S715 WeakPolarHBondContact O-CA 3.46Å; A712-S715 PolarHBondContact O-N 3.5Å; A712-V716 WeakPolarHBondContact O-CG2 3.42Å; A712-V716 PolarHBondContact O-N 3.13Å; A712-V722 HydrophobicContact CB-CG1 4.48Å; A712-V722 HydrophobicContact CB-CG2 4.36Å
713R94.2Very high94.3Very high112 Ų11246.9 Ų46.942%0.42325%0.253SS..Hα-helixtrans-60.4-43.7176.8-167.9-175.373.5-172.96.4113L416 F422 V709 S710 S715L416-R713 PolarHBondContact O-NH1 3.41Å; F422-R713 HydrophobicContact CE2-CB 4.33Å; F422-R713 HydrophobicContact CZ-CB 4.14Å; V709-R713 WeakPolarHBondContact O-CB 3.35Å; V709-R713 PolarHBondContact O-N 2.75Å; S710-R713 WeakPolarHBondContact O-CB 3.33Å; S710-R713 PolarHBondContact O-N 3.47Å; R713-S715 PolarHBondContact O-N 3.11Å
714E94.7Very high94.4Very high111 Ų11146 Ų4652%0.51925%0.25SS..Hα-helixtrans-62.8-21.1174.7-72.5160.4-14200112.9S710 K711 A712S710-E714 WeakPolarHBondContact O-CG 3.33Å; S710-E714 PolarHBondContact O-N 2.82Å; S710-E714 PolarHBondContact OG-OE1 2.86Å; K711-E714 WeakPolarHBondContact CD-OE2 3.35Å; K711-E714 IonicContact NZ-OE2 3.58Å; K711-E714 PolarHBondContact NZ-OE2 3.43Å; K711-E714 PolarHBondContact O-N 3.01Å; A712-E714 PolarHBondContact O-N 2.9Å
715S95.9Very high94.4Very high10 Ų1049.9 Ų49.97%0.0727%0.274CS..THydrogen-bonded Turntrans-109.47.9-171.6-54.60000113.6K711 A712 R713 Q717 Y723 T724K711-S715 VanDerWaalsContact O-CB 3.23Å; K711-S715 WeakPolarHBondContact O-CB 3.37Å; K711-S715 PolarHBondContact O-N 3.32Å; K711-S715 PolarHBondContact O-OG 2.77Å; A712-S715 CarbonylContact O-C 3.5Å; A712-S715 WeakPolarHBondContact O-CA 3.46Å; A712-S715 PolarHBondContact O-N 3.5Å; R713-S715 PolarHBondContact O-N 3.11Å; S715-Q717 PolarHBondContact O-N 3.06Å; S715-Q717 PolarHBondContact O-NE2 3.15Å; S715-Q717 VanDerWaalsContact O-NE2 3.12Å; S715-Y723 PolarHBondContact O-N 2.67Å; S715-T724 VanDerWaalsContact OG-CB 3.26Å; S715-T724 WeakPolarHBondContact OG-CB 3.49Å; S715-T724 WeakPolarHBondContact OG-CG2 3.4Å
716V95.4Very high94.4Very high39 Ų3951.8 Ų51.824%0.23629%0.29CS..BIsolated β-bridgetrans-66.2128177.3176.20000110F422 A712F422-V716 HydrophobicContact CE1-CG2 3.67Å; F422-V716 HydrophobicContact CZ-CG2 3.88Å; A712-V716 WeakPolarHBondContact O-CG2 3.42Å; A712-V716 PolarHBondContact O-N 3.13Å
717Q94.3Very high94.4Very high69 Ų6952.2 Ų52.232%0.32230%0.298SS..  trans-89.3164174.9-57.9-54.9-57.800110.9S715 D719 G720 S721 Y723S715-Q717 PolarHBondContact O-N 3.06Å; S715-Q717 PolarHBondContact O-NE2 3.15Å; S715-Q717 VanDerWaalsContact O-NE2 3.12Å; Q717-D719 WeakPolarHBondContact CB-OD1 3.49Å; Q717-D719 PolarHBondContact O-N 3.14Å; Q717-D719 VanDerWaalsContact O-N 3.12Å; Q717-G720 WeakPolarHBondContact O-CA 3.31Å; Q717-G720 PolarHBondContact O-N 2.89Å; Q717-S721 WeakPolarHBondContact CB-O 3.46Å; Q717-S721 WeakPolarHBondContact CG-O 3.39Å; Q717-S721 PolarHBondContact N-O 2.96Å; Q717-Y723 PolarHBondContact NE2-O 3.1Å; Q717-Y723 VanDerWaalsContact NE2-O 3.12Å
718P90.3Very high94.3Very high138 Ų13854.9 Ų54.990%0.89631%0.311SS*.THydrogen-bonded Turntrans-58-25.9178.1-26.835.8000114.8G720P718-G720 PolarHBondContact O-N 3.21Å
719D89Confident94.3Very high118 Ų11855 Ų5563%0.63131%0.312SS*.THydrogen-bonded Turntrans-81.60.717669.2-3.1000113.5Q717 S721Q717-D719 WeakPolarHBondContact CB-OD1 3.49Å; Q717-D719 PolarHBondContact O-N 3.14Å; Q717-D719 VanDerWaalsContact O-N 3.12Å; D719-S721 VanDerWaalsContact C-N 3.29Å; D719-S721 VanDerWaalsContact CG-OG 3.3Å; D719-S721 PolarHBondContact O-N 2.82Å; D719-S721 VanDerWaalsContact OD1-CB 3.25Å; D719-S721 WeakPolarHBondContact OD1-CB 3.29Å; D719-S721 PolarHBondContact OD1-N 3.34Å; D719-S721 PolarHBondContact OD1-OG 3.02Å; D719-S721 PolarHBondContact OD2-OG 3.42Å
720G86.6Confident94.5Very high50 Ų5055 Ų5552%0.51531%0.312SS..SBendtrans82.8-4.5-177.300000114.7Q717 P718Q717-G720 WeakPolarHBondContact O-CA 3.31Å; Q717-G720 PolarHBondContact O-N 2.89Å; P718-G720 PolarHBondContact O-N 3.21Å
721S92.1Very high94.6Very high31 Ų3153.5 Ų53.522%0.21730%0.301CS..  trans-75.2153.5174.971.10000111.6R537 Q717 D719R537-S721 PolarHBondContact NH2-OG 2.9Å; Q717-S721 WeakPolarHBondContact CB-O 3.46Å; Q717-S721 WeakPolarHBondContact CG-O 3.39Å; Q717-S721 PolarHBondContact N-O 2.96Å; D719-S721 VanDerWaalsContact C-N 3.29Å; D719-S721 VanDerWaalsContact CG-OG 3.3Å; D719-S721 PolarHBondContact O-N 2.82Å; D719-S721 VanDerWaalsContact OD1-CB 3.25Å; D719-S721 WeakPolarHBondContact OD1-CB 3.29Å; D719-S721 PolarHBondContact OD1-N 3.34Å; D719-S721 PolarHBondContact OD1-OG 3.02Å; D719-S721 PolarHBondContact OD2-OG 3.42Å
722V95.8Very high94.7Very high10 Ų1051.6 Ų51.66%0.06129%0.293CS..BIsolated β-bridgetrans-91.8127.3172.3177.60000109.3F422 D512 P542 A712F422-V722 HydrophobicContact CD1-CG2 3.79Å; F422-V722 HydrophobicContact CE1-CG2 3.79Å; D512-V722 HydrophobicContact CB-CB 4.11Å; D512-V722 HydrophobicContact CB-CG2 3.85Å; P542-V722 HydrophobicContact CG-CG1 4.32Å; A712-V722 HydrophobicContact CB-CG1 4.48Å; A712-V722 HydrophobicContact CB-CG2 4.36Å
723Y97.5Very high94.8Very high81 Ų8151.6 Ų51.632%0.31829%0.293SS..  trans-145.6125175.5-178-91000111.4R537 C540 S715 Q717 T725R537-Y723 HydrophobicContact CG-CD2 4.06Å; R537-Y723 HydrophobicContact CG-CE2 4.07Å; C540-Y723 HydrophobicContact CB-CD2 3.5Å; C540-Y723 VanDerWaalsContact CB-CD2 3.5Å; C540-Y723 HydrophobicContact CB-CE2 3.32Å; C540-Y723 HydrophobicContact CB-CG 4.3Å; C540-Y723 CarbonylContact O-C 3.57Å; C540-Y723 VanDerWaalsContact O-CA 3.29Å; C540-Y723 WeakPolarHBondContact O-CA 3.47Å; C540-Y723 VanDerWaalsContact SG-CE2 3.58Å; S715-Y723 PolarHBondContact O-N 2.67Å; Q717-Y723 PolarHBondContact NE2-O 3.1Å; Q717-Y723 VanDerWaalsContact NE2-O 3.12Å; Y723-T725 HydrophobicContact CE1-CG2 4.25Å
724T96.9Very high94.8Very high15 Ų1546.3 Ų46.39%0.09227%0.273CS..  trans-153.3139.2175.8179.20000112.5C540 P542 S715 A726 S729C540-T724 CarbonylContact C-O 3.59Å; C540-T724 VanDerWaalsContact C-O 3.23Å; C540-T724 WeakPolarHBondContact CA-O 3.46Å; C540-T724 WeakPolarHBondContact CB-O 3.43Å; C540-T724 PolarHBondContact O-N 2.87Å; P542-T724 HydrophobicContact CG-CG2 4.06Å; S715-T724 VanDerWaalsContact OG-CB 3.26Å; S715-T724 WeakPolarHBondContact OG-CB 3.49Å; S715-T724 WeakPolarHBondContact OG-CG2 3.4Å; T724-A726 WeakPolarHBondContact OG1-CB 3.14Å; T724-A726 PolarHBondContact OG1-N 3.41Å; T724-A726 VanDerWaalsContact OG1-N 3.16Å; T724-S729 WeakPolarHBondContact CG2-OG 3.29Å; T724-S729 PolarHBondContact OG1-OG 3.05Å
725T95.5Very high94.6Very high82 Ų8242.7 Ų42.750%0.50326%0.257SS..  trans-113.85.8169.556.60000112.1C540 Y723C540-T725 HydrophobicContact CB-CG2 4.47Å; Y723-T725 HydrophobicContact CE1-CG2 4.25Å
726A95.2Very high94.1Very high40 Ų4046.1 Ų46.133%0.33127%0.268SS..  trans-59.6140.8-178.700000110.9R533 T724 D728 S729R533-A726 PolarHBondContact NH1-O 3.41Å; T724-A726 WeakPolarHBondContact OG1-CB 3.14Å; T724-A726 PolarHBondContact OG1-N 3.41Å; T724-A726 VanDerWaalsContact OG1-N 3.16Å; A726-D728 WeakPolarHBondContact CB-OD1 2.83Å; A726-D728 PolarHBondContact O-N 2.77Å; A726-S729 PolarHBondContact O-N 3.4Å; A726-S729 VanDerWaalsContact O-N 3.15Å; A726-S729 PolarHBondContact O-OG 2.85Å
727V93Very high93.1Very high89 Ų8951.9 Ų51.954%0.53929%0.293SS..G310 helixtrans-67.9-28.9-174.1178.40000111.5S729 S744 M746V727-S729 VanDerWaalsContact C-N 3.32Å; V727-S744 WeakPolarHBondContact CG1-OG 3.16Å; V727-S744 WeakPolarHBondContact O-CB 3.23Å; V727-S744 PolarHBondContact O-OG 2.98Å; V727-M746 HydrophobicContact CG1-CB 4.18Å; V727-M746 HydrophobicContact CG1-CG 4.45Å
728D94.9Very high92.1Very high81 Ų8152.9 Ų52.943%0.43329%0.294SS..G310 helixtrans-84.92.2177.272.2-32.9000113.7K711 A726 V731K711-D728 IonicContact NZ-OD2 2.83Å; K711-D728 PolarHBondContact NZ-OD2 2.85Å; A726-D728 WeakPolarHBondContact CB-OD1 2.83Å; A726-D728 PolarHBondContact O-N 2.77Å; D728-V731 VanDerWaalsContact O-CG1 3.25Å; D728-V731 WeakPolarHBondContact O-CG1 3.43Å
729S96.8Very high91.7Very high3 Ų351.6 Ų51.62%0.02128%0.276CS..G310 helixtrans-90.5-11.8171.973.90000113.1R533 P542 M543 T724 A726 V727R533-S729 PolarHBondContact NH1-OG 3.49Å; R533-S729 VanDerWaalsContact NH1-OG 3.09Å; R533-S729 PolarHBondContact NH2-OG 3.32Å; P542-S729 CarbonylContact C-O 3.56Å; P542-S729 VanDerWaalsContact CA-O 3.24Å; P542-S729 WeakPolarHBondContact CA-O 3.48Å; M543-S729 PolarHBondContact N-O 2.88Å; T724-S729 WeakPolarHBondContact CG2-OG 3.29Å; T724-S729 PolarHBondContact OG1-OG 3.05Å; A726-S729 PolarHBondContact O-N 3.4Å; A726-S729 VanDerWaalsContact O-N 3.15Å; A726-S729 PolarHBondContact O-OG 2.85Å; V727-S729 VanDerWaalsContact C-N 3.32Å
730A98.3Very high91.6Very high0 Ų047.2 Ų47.20%025%0.254CS..EExtended strand (participates in β ladder)trans-117.9100.2171.400000110T530 M543 S744 V745T530-A730 HydrophobicContact CG2-CB 3.87Å; T530-A730 WeakPolarHBondContact OG1-CB 3.47Å; M543-A730 HydrophobicContact CB-CB 4.46Å; M543-A730 HydrophobicContact CE-CB 3.98Å; M543-A730 WeakPolarHBondContact O-CA 3.49Å; A730-S744 WeakPolarHBondContact O-CA 3.28Å; A730-V745 HydrophobicContact CB-CG2 4.03Å; A730-V745 PolarHBondContact O-N 2.84Å
731V98.3Very high91.9Very high5 Ų549.2 Ų49.23%0.0325%0.25CC..EExtended strand (participates in β ladder)trans-129.8155.6-167.2-62.70000112.8M543 V544 T545 D728 C742 V743M543-V731 PolarHBondContact O-N 2.91Å; V544-V731 CarbonylContact C-O 3.52Å; V544-V731 WeakPolarHBondContact CA-O 3.39Å; V544-V731 HydrophobicContact CB-CG2 4.45Å; V544-V731 HydrophobicContact CG1-CG2 4.43Å; V544-V731 HydrophobicContact CG2-CG2 3.84Å; T545-V731 PolarHBondContact N-O 3.26Å; D728-V731 VanDerWaalsContact O-CG1 3.25Å; D728-V731 WeakPolarHBondContact O-CG1 3.43Å; V731-C742 HydrophobicContact CB-CB 4Å; V731-C742 HydrophobicContact CG1-CB 4.22Å; V731-C742 HydrophobicContact CG2-CB 3.9Å; V731-V743 CarbonylContact C-O 3.53Å; V731-V743 WeakPolarHBondContact CA-O 3.33Å; V731-V743 WeakPolarHBondContact CB-O 3.46Å
732L98.1Very high92.1Very high0 Ų049.8 Ų49.80%025%0.253CS..EExtended strand (participates in β ladder)trans-103123.7162.8-178.8147.2000108.1F523 T545 P547 I554 G734 V743 V745 L748F523-L732 HydrophobicContact CB-CD1 4.24Å; F523-L732 HydrophobicContact CD2-CD1 3.96Å; F523-L732 HydrophobicContact CG-CD1 4.36Å; T545-L732 CarbonylContact O-C 3.45Å; T545-L732 WeakPolarHBondContact O-CA 3.05Å; P547-L732 HydrophobicContact CG-CD1 3.98Å; P547-L732 HydrophobicContact CG-CD2 3.61Å; P547-L732 HydrophobicContact CG-CG 3.78Å; I554-L732 HydrophobicContact CG2-CD1 3.64Å; L732-G734 PolarHBondContact O-N 3.43Å; L732-V743 PolarHBondContact N-O 3.17Å; L732-V743 PolarHBondContact O-N 3.5Å; L732-V745 HydrophobicContact CB-CG1 4.41Å; L732-L748 HydrophobicContact CB-CD1 3.61Å; L732-L748 HydrophobicContact CD1-CD1 3.98Å; L732-L748 HydrophobicContact CD2-CD1 4.02Å; L732-L748 HydrophobicContact CG-CD1 4.09Å
733L97.6Very high92Very high0 Ų049.5 Ų49.50%025%0.252CS..EExtended strand (participates in β ladder)trans-88.5100.9174.2175.157.2000108.7V544 T545 P547 M700 Q703 A704 E741V544-L733 HydrophobicContact CG1-CB 4.09Å; T545-L733 PolarHBondContact O-N 3.29Å; P547-L733 WeakPolarHBondContact CD-O 3.21Å; M700-L733 HydrophobicContact CB-CD2 4.28Å; M700-L733 HydrophobicContact CE-CG 3.98Å; M700-L733 WeakPolarHBondContact CE-O 3.33Å; M700-L733 WeakPolarHBondContact O-CD2 3.38Å; Q703-L733 HydrophobicContact CB-CD2 3.97Å; Q703-L733 HydrophobicContact CG-CD1 4.35Å; Q703-L733 HydrophobicContact CG-CD2 3.98Å; A704-L733 HydrophobicContact CB-CD2 4.06Å; L733-E741 WeakPolarHBondContact CA-O 3.13Å
734G94.6Very high92Very high0 Ų046.2 Ų46.20%024%0.241CC..EExtended strand (participates in β ladder)trans-120.3179.1-176.700000112.7L732 S740 E741L732-G734 PolarHBondContact O-N 3.43Å; G734-S740 CarbonylContact O-C 3.5Å; G734-S740 VanDerWaalsContact O-CA 3.26Å; G734-S740 WeakPolarHBondContact O-CA 3.31Å; G734-E741 PolarHBondContact N-O 3.16Å; G734-E741 PolarHBondContact O-N 3Å
735I90.7Very high92Very high35 Ų3545.5 Ų45.518%0.17924%0.236CC..EExtended strand (participates in β ladder)trans-107.4110.7169.3-64.5169.2000108.7T557 S558 I559 L696 M700 H739T557-I735 PolarHBondContact OG1-N 3.38Å; S558-I735 WeakPolarHBondContact CB-O 3.48Å; S558-I735 PolarHBondContact N-O 3.44Å; S558-I735 PolarHBondContact OG-O 2.92Å; I559-I735 HydrophobicContact CG2-CB 4.36Å; I559-I735 HydrophobicContact CG2-CD1 3.51Å; I559-I735 HydrophobicContact CG2-CG1 4.43Å; L696-I735 HydrophobicContact CD1-CD1 3.6Å; M700-I735 HydrophobicContact CE-CG1 4.36Å; M700-I735 HydrophobicContact SD-CD1 4.39Å; M700-I735 HydrophobicContact SD-CG1 4.48Å; I735-H739 WeakPolarHBondContact CA-O 3.3Å
736R84.8Confident92.1Very high82 Ų8245 Ų4531%0.30923%0.229SC..EExtended strand (participates in β ladder)trans-110.8131.1171.2-66-174.975.4179.86109.4G556 R738 H739 E747G556-R736 WeakPolarHBondContact O-CG 3.42Å; R736-R738 PolarHBondContact O-N 3.34Å; R736-H739 PolarHBondContact N-O 3.49Å; R736-H739 PolarHBondContact O-N 3.44Å; R736-H739 VanDerWaalsContact O-O 3.13Å; R736-E747 IonicContact NH1-OE1 3.72Å
737E74.2Confident92.1Very high161 Ų16147.8 Ų47.875%0.75224%0.235SC*.THydrogen-bonded Turntrans52-92-176.3-53.8-175.4166.300113G356G356-E737 CarbonylContact C-O 3.53Å
738R73.9Confident92.2Very high90 Ų9043.6 Ų43.634%0.3421%0.21SC..THydrogen-bonded Turntrans-122.6-2.9-173.5-52.4-174.6173.6-178.1-6.3113.6R736R736-R738 PolarHBondContact O-N 3.34Å
739H81.6Confident92.3Very high111 Ų11143.8 Ų43.851%0.51421%0.207SC..EExtended strand (participates in β ladder)trans-132.9145.5-167.4-59.6-54.4000111.6I735 R736I735-H739 WeakPolarHBondContact CA-O 3.3Å; R736-H739 PolarHBondContact N-O 3.49Å; R736-H739 PolarHBondContact O-N 3.44Å; R736-H739 VanDerWaalsContact O-O 3.13Å
740S88Confident92.1Very high26 Ų2652.1 Ų52.118%0.18225%0.245CC..EExtended strand (participates in β ladder)trans-74.6120.8165.555.90000108.4R396 Q703 G734R396-S740 PolarHBondContact NH1-OG 3.27Å; R396-S740 PolarHBondContact NH2-OG 3.29Å; Q703-S740 VanDerWaalsContact OE1-CB 3.24Å; Q703-S740 PolarHBondContact OE1-OG 3.27Å; G734-S740 CarbonylContact O-C 3.5Å; G734-S740 VanDerWaalsContact O-CA 3.26Å; G734-S740 WeakPolarHBondContact O-CA 3.31Å
741E92.2Very high91.9Very high91 Ų9154 Ų5443%0.42525%0.254SS..EExtended strand (participates in β ladder)trans-132140.7-173.1-173.9176.4-158.300110.4L733 G734 V743L733-E741 WeakPolarHBondContact CA-O 3.13Å; G734-E741 PolarHBondContact N-O 3.16Å; G734-E741 PolarHBondContact O-N 3Å; E741-V743 HydrophobicContact CB-CG2 4.47Å; E741-V743 HydrophobicContact CG-CG2 4.01Å
742C95.4Very high91.7Very high43 Ų4354.5 Ų54.529%0.29126%0.258SS..EExtended strand (participates in β ladder)trans-90.2110.7169.8-69.80000108.4V731V731-C742 HydrophobicContact CB-CB 4Å; V731-C742 HydrophobicContact CG1-CB 4.22Å; V731-C742 HydrophobicContact CG2-CB 3.9Å
743V95.5Very high91.6Very high5 Ų556.3 Ų56.33%0.0327%0.268CS..EExtended strand (participates in β ladder)trans-109.1138.9178.1-172.80000108.9V731 L732 E741 V745 E747 L748V731-V743 CarbonylContact C-O 3.53Å; V731-V743 WeakPolarHBondContact CA-O 3.33Å; V731-V743 WeakPolarHBondContact CB-O 3.46Å; L732-V743 PolarHBondContact N-O 3.17Å; L732-V743 PolarHBondContact O-N 3.5Å; E741-V743 HydrophobicContact CB-CG2 4.47Å; E741-V743 HydrophobicContact CG-CG2 4.01Å; V743-V745 PolarHBondContact O-N 2.99Å; V743-E747 HydrophobicContact CG1-CB 4.34Å; V743-E747 HydrophobicContact CG1-CG 4.43Å; V743-L748 HydrophobicContact CB-CD1 4.27Å; V743-L748 HydrophobicContact CB-CD2 4.35Å; V743-L748 HydrophobicContact CB-CG 4.29Å; V743-L748 HydrophobicContact CG1-CD1 4.38Å; V743-L748 HydrophobicContact CG1-CD2 3.8Å; V743-L748 HydrophobicContact CG1-CG 3.85Å
744S96.9Very high91.4Very high12 Ų1259.6 Ų59.68%0.08428%0.283CS..EExtended strand (participates in β ladder)trans-60.4137178.6-178.40000111.4V727 A730 M746 E747 L748V727-S744 WeakPolarHBondContact CG1-OG 3.16Å; V727-S744 WeakPolarHBondContact O-CB 3.23Å; V727-S744 PolarHBondContact O-OG 2.98Å; A730-S744 WeakPolarHBondContact O-CA 3.28Å; S744-M746 PolarHBondContact O-N 3.15Å; S744-M746 PolarHBondContact OG-N 2.98Å; S744-E747 PolarHBondContact O-N 3.44Å; S744-L748 WeakPolarHBondContact O-CG 3.25Å; S744-L748 PolarHBondContact O-N 3.42Å; S744-L748 VanDerWaalsContact O-N 3.13Å
745V97.4Very high91.4Very high0 Ų067.1 Ų67.10%032%0.318CS..Hα-helixtrans-63.6-25.7174.4-620000112.3F523 C526 L527 T530 A730 L732 V743 L748 K749F523-V745 HydrophobicContact CD2-CB 4.36Å; F523-V745 HydrophobicContact CD2-CG1 4.14Å; F523-V745 HydrophobicContact CE2-CB 4Å; F523-V745 HydrophobicContact CE2-CG1 4.24Å; C526-V745 HydrophobicContact CB-CG1 4.13Å; L527-V745 HydrophobicContact CB-CB 4.49Å; L527-V745 HydrophobicContact CB-CG2 4.44Å; L527-V745 HydrophobicContact CD1-CG2 4.26Å; T530-V745 HydrophobicContact CG2-CG2 4.4Å; A730-V745 HydrophobicContact CB-CG2 4.03Å; A730-V745 PolarHBondContact O-N 2.84Å; L732-V745 HydrophobicContact CB-CG1 4.41Å; V743-V745 PolarHBondContact O-N 2.99Å; V745-L748 PolarHBondContact O-N 3.03Å; V745-K749 PolarHBondContact O-N 3.27Å; V745-K749 VanDerWaalsContact O-N 3.15Å
746M96.4Very high91.6Very high70 Ų7069.8 Ų69.835%0.34533%0.326SS..Hα-helixtrans-69.1-39.9175.2-67.3-60.8-64.900111.8L527 T530 E531 V727 S744 K749L527-M746 HydrophobicContact CD1-SD 3.52Å; L527-M746 VanDerWaalsContact CD1-SD 3.52Å; T530-M746 HydrophobicContact CG2-CG 3.96Å; T530-M746 HydrophobicContact CG2-SD 4.08Å; E531-M746 HydrophobicContact CG-CE 4.3Å; E531-M746 HydrophobicContact CG-SD 3.94Å; V727-M746 HydrophobicContact CG1-CB 4.18Å; V727-M746 HydrophobicContact CG1-CG 4.45Å; S744-M746 PolarHBondContact O-N 3.15Å; S744-M746 PolarHBondContact OG-N 2.98Å; M746-K749 VanDerWaalsContact O-CB 3.27Å; M746-K749 WeakPolarHBondContact O-CB 3.23Å; M746-K749 PolarHBondContact O-N 3.42Å
747E95.3Very high92.1Very high100 Ų10070.3 Ų70.347%0.46733%0.328SS..Hα-helixtrans-66-41.5174.6-175.1-170145.100110.8R736 V743 S744 K749R736-E747 IonicContact NH1-OE1 3.72Å; V743-E747 HydrophobicContact CG1-CB 4.34Å; V743-E747 HydrophobicContact CG1-CG 4.43Å; S744-E747 PolarHBondContact O-N 3.44Å; E747-K749 PolarHBondContact O-N 2.91Å
748L95.7Very high93Very high0 Ų063 Ų630%029%0.294CS..Hα-helixtrans-70-16179.8-65.6179.8000113.8F523 P555 L732 V743 S744 V745 E750 Q751 A752F523-L748 HydrophobicContact CE2-CB 3.74Å; F523-L748 HydrophobicContact CE2-CD1 4.35Å; F523-L748 HydrophobicContact CZ-CB 3.98Å; P555-L748 HydrophobicContact CB-CB 4.36Å; P555-L748 HydrophobicContact CB-CD2 4.37Å; P555-L748 HydrophobicContact CG-CB 4.27Å; L732-L748 HydrophobicContact CB-CD1 3.61Å; L732-L748 HydrophobicContact CD1-CD1 3.98Å; L732-L748 HydrophobicContact CD2-CD1 4.02Å; L732-L748 HydrophobicContact CG-CD1 4.09Å; V743-L748 HydrophobicContact CB-CD1 4.27Å; V743-L748 HydrophobicContact CB-CD2 4.35Å; V743-L748 HydrophobicContact CB-CG 4.29Å; V743-L748 HydrophobicContact CG1-CD1 4.38Å; V743-L748 HydrophobicContact CG1-CD2 3.8Å; V743-L748 HydrophobicContact CG1-CG 3.85Å; S744-L748 WeakPolarHBondContact O-CG 3.25Å; S744-L748 PolarHBondContact O-N 3.42Å; S744-L748 VanDerWaalsContact O-N 3.13Å; V745-L748 PolarHBondContact O-N 3.03Å; L748-E750 PolarHBondContact O-N 3.49Å; L748-Q751 PolarHBondContact O-N 3.11Å; L748-A752 PolarHBondContact O-N 3.4Å
749K95.9Very high93.9Very high85 Ų8559.4 Ų59.437%0.3728%0.282SS..G310 helixtrans-56-40.4176.7-177.7179.7178.3176.60111.7L527 E531 V745 M746 E747 Q751 A752 F754L527-K749 HydrophobicContact CD1-CB 4.32Å; L527-K749 HydrophobicContact CD1-CD 4.33Å; L527-K749 HydrophobicContact CD2-CB 4.07Å; L527-K749 HydrophobicContact CD2-CD 4.12Å; L527-K749 HydrophobicContact CD2-CG 3.89Å; E531-K749 WeakPolarHBondContact OE1-CE 3.32Å; E531-K749 IonicContact OE1-NZ 2.84Å; E531-K749 PolarHBondContact OE1-NZ 3.45Å; V745-K749 PolarHBondContact O-N 3.27Å; V745-K749 VanDerWaalsContact O-N 3.15Å; M746-K749 VanDerWaalsContact O-CB 3.27Å; M746-K749 WeakPolarHBondContact O-CB 3.23Å; M746-K749 PolarHBondContact O-N 3.42Å; E747-K749 PolarHBondContact O-N 2.91Å; K749-Q751 PolarHBondContact O-N 3.47Å; K749-A752 PolarHBondContact O-N 2.84Å; K749-F754 HydrophobicContact CG-CE2 4Å; K749-F754 HydrophobicContact CG-CZ 4.05Å
750E93Very high94.2Very high178 Ų17857.9 Ų57.983%0.83228%0.281SS*.G310 helixtrans-72.4-17.7179.7-61.7-175.3170.700112.8L748L748-E750 PolarHBondContact O-N 3.49Å
751Q93.7Very high94.1Very high41 Ų4161.5 Ų61.519%0.19230%0.298CS..G310 helixtrans-97.29.3-180-60.3174.735.900112.6P555 L748 K749 T760P555-Q751 HydrophobicContact CB-CB 4.16Å; L748-Q751 PolarHBondContact O-N 3.11Å; K749-Q751 PolarHBondContact O-N 3.47Å; Q751-T760 WeakPolarHBondContact CA-OG1 3.26Å; Q751-T760 PolarHBondContact O-N 3.34Å; Q751-T760 PolarHBondContact O-OG1 2.99Å
752A95.1Very high93.9Very high14 Ų1461 Ų6112%0.11629%0.292CS..EExtended strand (participates in β ladder)trans-117.6125.3-174.200000112.2F520 F523 P555 L748 K749 F754 L758F520-A752 HydrophobicContact CE2-CB 4.29Å; F520-A752 HydrophobicContact CZ-CB 4.12Å; F523-A752 HydrophobicContact CE1-CB 3.93Å; F523-A752 HydrophobicContact CZ-CB 4.37Å; P555-A752 HydrophobicContact CG-CB 4.11Å; L748-A752 PolarHBondContact O-N 3.4Å; K749-A752 PolarHBondContact O-N 2.84Å; A752-F754 HydrophobicContact CB-CD2 4.16Å; A752-F754 HydrophobicContact CB-CE2 3.67Å; A752-F754 HydrophobicContact CB-CZ 3.85Å; A752-F754 WeakPolarHBondContact O-CD2 3.41Å; A752-F754 PolarHBondContact O-N 3.16Å; A752-L758 WeakPolarHBondContact CA-O 3.28Å
753D95.3Very high93.6Very high38 Ų3861.8 Ų61.820%0.20329%0.289CS..EExtended strand (participates in β ladder)trans-86.1102.3161.7178.8-19.7000107.7E755 R756 R757 L758D753-E755 PolarHBondContact OD1-N 2.83Å; D753-R756 PolarHBondContact OD1-N 2.99Å; D753-R756 WeakPolarHBondContact OD2-CB 3.5Å; D753-R756 WeakPolarHBondContact OD2-CD 3.3Å; D753-R756 WeakPolarHBondContact OD2-CG 3.5Å; D753-R756 IonicContact OD2-CZ 3.91Å; D753-R756 IonicContact OD2-NH1 2.82Å; D753-R756 PolarHBondContact OD2-NH1 3.16Å; D753-R757 CarbonylContact O-C 3.52Å; D753-R757 WeakPolarHBondContact O-CA 3.35Å; D753-R757 PolarHBondContact O-N 3.1Å; D753-L758 HydrophobicContact CB-CB 4.21Å; D753-L758 PolarHBondContact N-O 2.7Å; D753-L758 PolarHBondContact O-N 3.01Å
754F94.3Very high93.4Very high69 Ų6961.8 Ų61.830%0.30329%0.289SS..THydrogen-bonded Turntrans-73.1-26.8-178.2-69.8-91000113.6F520 F523 H524 L527 K749 A752F520-F754 AromaticContact CE1-CD1 3.71Å; F520-F754 HydrophobicContact CE1-CD1 3.71Å; F520-F754 HydrophobicContact CE1-CE1 4.19Å; F520-F754 HydrophobicContact CE1-CG 4.39Å; F520-F754 AromaticContact CZ-CD1 3.89Å; F520-F754 HydrophobicContact CZ-CD1 3.89Å; F520-F754 HydrophobicContact CZ-CE1 4.23Å; F520-F754 HydrophobicContact CZ-CG 4.27Å; F523-F754 HydrophobicContact CE1-CE1 4.09Å; F523-F754 HydrophobicContact CE1-CZ 4.1Å; F523-F754 HydrophobicContact CZ-CZ 4.47Å; H524-F754 AromaticContact CD2-CE1 3.8Å; L527-F754 HydrophobicContact CD2-CE1 3.81Å; L527-F754 HydrophobicContact CD2-CZ 3.47Å; L527-F754 VanDerWaalsContact CD2-CZ 3.47Å; K749-F754 HydrophobicContact CG-CE2 4Å; K749-F754 HydrophobicContact CG-CZ 4.05Å; A752-F754 HydrophobicContact CB-CD2 4.16Å; A752-F754 HydrophobicContact CB-CE2 3.67Å; A752-F754 HydrophobicContact CB-CZ 3.85Å; A752-F754 WeakPolarHBondContact O-CD2 3.41Å; A752-F754 PolarHBondContact O-N 3.16Å
755E93.8Very high93.2Very high159 Ų15963.1 Ų63.174%0.74330%0.295SS*.THydrogen-bonded Turntrans-69.8-48179.4-173.1-172.8173.700109.8D753D753-E755 PolarHBondContact OD1-N 2.83Å
756R94.2Very high92.9Very high90 Ų9066.2 Ų66.234%0.3431%0.308SS..THydrogen-bonded Turntrans-92.9-10.5-178.9-56.3-174.4-174.7904.3113.3Y597 F617 D753 L758Y597-R756 HydrophobicContact CD2-CB 3.83Å; Y597-R756 HydrophobicContact CD2-CG 4.33Å; Y597-R756 WeakPolarHBondContact CD2-O 3.15Å; Y597-R756 HydrophobicContact CE2-CB 4.4Å; Y597-R756 HydrophobicContact CG-CB 4.11Å; F617-R756 VanDerWaalsContact CZ-CD 3.42Å; D753-R756 PolarHBondContact OD1-N 2.99Å; D753-R756 WeakPolarHBondContact OD2-CB 3.5Å; D753-R756 WeakPolarHBondContact OD2-CD 3.3Å; D753-R756 WeakPolarHBondContact OD2-CG 3.5Å; D753-R756 IonicContact OD2-CZ 3.91Å; D753-R756 IonicContact OD2-NH1 2.82Å; D753-R756 PolarHBondContact OD2-NH1 3.16Å; R756-L758 HydrophobicContact CB-CD1 3.97Å; R756-L758 HydrophobicContact CB-CG 4.05Å
757R95.7Very high92.8Very high93 Ų9363 Ų6335%0.35129%0.292SS..THydrogen-bonded Turntrans57.258.3-175-59.5177.1-69.6176.3-4.9111.3F520 E521 N553 D753F520-R757 HydrophobicContact CB-CB 4.14Å; F520-R757 HydrophobicContact CD1-CB 3.84Å; F520-R757 HydrophobicContact CD1-CG 3.63Å; F520-R757 HydrophobicContact CD2-CB 3.86Å; F520-R757 HydrophobicContact CE1-CB 4.17Å; F520-R757 HydrophobicContact CE1-CG 3.9Å; F520-R757 HydrophobicContact CE2-CB 4.19Å; F520-R757 HydrophobicContact CG-CB 3.67Å; F520-R757 HydrophobicContact CG-CG 3.99Å; F520-R757 HydrophobicContact CZ-CB 4.34Å; F520-R757 HydrophobicContact CZ-CG 4.48Å; E521-R757 IonicContact OE1-CZ 3.28Å; E521-R757 IonicContact OE1-NH1 3.13Å; E521-R757 PolarHBondContact OE1-NH1 3.21Å; N553-R757 PolarHBondContact ND2-O 3.27Å; D753-R757 CarbonylContact O-C 3.52Å; D753-R757 WeakPolarHBondContact O-CA 3.35Å; D753-R757 PolarHBondContact O-N 3.1Å
758L93.3Very high92.6Very high9 Ų958.2 Ų58.25%0.04727%0.27CS..EExtended strand (participates in β ladder)trans-124.7153.8-178.7-66.2176.2000112.3N553 C598 F617 A752 D753 R756N553-L758 HydrophobicContact CB-CD2 4.39Å; C598-L758 HydrophobicContact CB-CD2 3.64Å; F617-L758 HydrophobicContact CD1-CD1 4.09Å; F617-L758 HydrophobicContact CE1-CD1 4.13Å; A752-L758 WeakPolarHBondContact CA-O 3.28Å; D753-L758 HydrophobicContact CB-CB 4.21Å; D753-L758 PolarHBondContact N-O 2.7Å; D753-L758 PolarHBondContact O-N 3.01Å; R756-L758 HydrophobicContact CB-CD1 3.97Å; R756-L758 HydrophobicContact CB-CG 4.05Å
759S92.5Very high92.4Very high13 Ų1359.7 Ų59.79%0.09128%0.28CS..EExtended strand (participates in β ladder)trans-81.7140.8161.2176.50000109.7N553 D761 R762N553-S759 PolarHBondContact O-N 3.48Å; S759-D761 PolarHBondContact OG-N 3.32Å; S759-D761 PolarHBondContact OG-O 3.2Å; S759-R762 WeakPolarHBondContact O-CG 3.49Å
760T87.8Confident92.2Very high79 Ų7956.6 Ų56.649%0.48527%0.267SS..SBendtrans-70.1-36.4170.955.20000111.5Q751 R762Q751-T760 WeakPolarHBondContact CA-OG1 3.26Å; Q751-T760 PolarHBondContact O-N 3.34Å; Q751-T760 PolarHBondContact O-OG1 2.99Å; T760-R762 PolarHBondContact O-N 3.21Å; T760-R762 PolarHBondContact O-NE 3.44Å
761D85.9Confident92.3Very high102 Ų10248.2 Ų48.255%0.54523%0.228SC..  trans-77.8116172.2-176.811.3000110.8S759 W763S759-D761 PolarHBondContact OG-N 3.32Å; S759-D761 PolarHBondContact OG-O 3.2Å; D761-W763 PolarHBondContact OD1-N 3.5Å
762R88.6Confident92.1Very high80 Ų8047.4 Ų47.430%0.30222%0.223SC..  trans-129.560.8-174.1-67.4171.1-74.5171.20.7110.4S759 T760 W764 L765S759-R762 WeakPolarHBondContact O-CG 3.49Å; T760-R762 PolarHBondContact O-N 3.21Å; T760-R762 PolarHBondContact O-NE 3.44Å; R762-W764 PolarHBondContact O-N 3Å; R762-L765 HydrophobicContact CB-CD1 3.7Å; R762-L765 HydrophobicContact CB-CG 4.05Å; R762-L765 WeakPolarHBondContact O-CB 3.2Å; R762-L765 PolarHBondContact O-N 2.96Å
763W89.1Confident92Very high61 Ų6147.5 Ų47.523%0.23122%0.221CC..G310 helixtrans-47.9-33-175.672.7-95.4000114.7S558 Y600 D761 L765 K766 L767S558-W763 PolarHBondContact O-NE1 3.44Å; Y600-W763 AromaticContact CE2-CZ2 3.99Å; Y600-W763 HydrophobicContact CE2-CZ2 3.99Å; D761-W763 PolarHBondContact OD1-N 3.5Å; W763-L765 PolarHBondContact O-N 3.45Å; W763-K766 WeakPolarHBondContact O-CB 3.25Å; W763-K766 VanDerWaalsContact O-CD 3.22Å; W763-K766 WeakPolarHBondContact O-CD 3.26Å; W763-K766 WeakPolarHBondContact O-CG 3.11Å; W763-K766 PolarHBondContact O-N 3.45Å; W763-L767 HydrophobicContact CH2-CD1 4.48Å; W763-L767 HydrophobicContact CZ3-CD1 3.91Å
764W92Very high91.9Very high5 Ų545.8 Ų45.82%0.01921%0.212CC..G310 helixtrans-71.7-16.1-175.554.7-94.4000113.1G599 Y600 T603 I616 E618 R762 K766 L767G599-W764 VanDerWaalsContact CA-CH2 3.4Å; Y600-W764 HydrophobicContact CD2-CB 4.12Å; Y600-W764 AromaticContact CD2-CD1 3.54Å; Y600-W764 HydrophobicContact CD2-CD2 4.38Å; Y600-W764 AromaticContact CD2-CG 3.74Å; Y600-W764 HydrophobicContact CD2-CG 3.74Å; T603-W764 HydrophobicContact CG2-CE3 3.98Å; T603-W764 HydrophobicContact CG2-CZ3 4.25Å; T603-W764 VanDerWaalsContact OG1-CZ3 3.29Å; T603-W764 WeakPolarHBondContact OG1-CZ3 3.43Å; I616-W764 HydrophobicContact CD1-CH2 4.04Å; I616-W764 HydrophobicContact CD1-CZ3 3.85Å; E618-W764 VanDerWaalsContact CD-CH2 3.42Å; E618-W764 HydrophobicContact CG-CH2 4.12Å; E618-W764 HydrophobicContact CG-CZ2 4.41Å; E618-W764 VanDerWaalsContact OE1-CH2 3.26Å; E618-W764 WeakPolarHBondContact OE1-CH2 3.19Å; E618-W764 WeakPolarHBondContact OE1-CZ2 3.14Å; R762-W764 PolarHBondContact O-N 3Å; W764-K766 PolarHBondContact O-N 3.23Å; W764-L767 WeakPolarHBondContact O-CB 3.38Å; W764-L767 PolarHBondContact O-N 3.2Å
765L93Very high91.7Very high40 Ų4042.6 Ų42.621%0.20920%0.198CC..G310 helixtrans-60.3-27.7172.4-72.3174000112I616 E618 R762 W763 L767 R768I616-L765 HydrophobicContact CD1-CD2 3.82Å; E618-L765 HydrophobicContact CB-CD1 4.26Å; E618-L765 HydrophobicContact CB-CD2 3.98Å; R762-L765 HydrophobicContact CB-CD1 3.7Å; R762-L765 HydrophobicContact CB-CG 4.05Å; R762-L765 WeakPolarHBondContact O-CB 3.2Å; R762-L765 PolarHBondContact O-N 2.96Å; W763-L765 PolarHBondContact O-N 3.45Å; L765-L767 PolarHBondContact O-N 3.41Å; L765-R768 HydrophobicContact CD2-CG 4.1Å; L765-R768 VanDerWaalsContact O-CB 3.25Å; L765-R768 WeakPolarHBondContact O-CB 3.42Å; L765-R768 VanDerWaalsContact O-CG 3.28Å; L765-R768 WeakPolarHBondContact O-CG 3.4Å; L765-R768 PolarHBondContact O-N 2.79Å
766K91.1Very high91.1Very high64 Ų6435.8 Ų35.828%0.27817%0.171SC..G310 helixtrans-62-16.1174.684.9-165.6177.9-177.10113.4G21 W763 W764 P769G21-K766 WeakPolarHBondContact CA-O 3.49Å; G21-K766 PolarHBondContact N-O 3.25Å; W763-K766 WeakPolarHBondContact O-CB 3.25Å; W763-K766 VanDerWaalsContact O-CD 3.22Å; W763-K766 WeakPolarHBondContact O-CD 3.26Å; W763-K766 WeakPolarHBondContact O-CG 3.11Å; W763-K766 PolarHBondContact O-N 3.45Å; W764-K766 PolarHBondContact O-N 3.23Å; K766-P769 WeakPolarHBondContact O-CD 3.29Å
767L92.7Very high89.7Confident2 Ų231.9 Ų31.91%0.0116%0.157CC..G310 helixtrans-89.5-10.8176.9-57.2179000113R331 L604 L607 W763 W764 L765 L770 M771R331-L767 HydrophobicContact CG-CD2 4.38Å; L604-L767 HydrophobicContact CD2-CD1 3.54Å; L607-L767 HydrophobicContact CD2-CB 4.32Å; L607-L767 HydrophobicContact CD2-CD1 4.49Å; W763-L767 HydrophobicContact CH2-CD1 4.48Å; W763-L767 HydrophobicContact CZ3-CD1 3.91Å; W764-L767 WeakPolarHBondContact O-CB 3.38Å; W764-L767 PolarHBondContact O-N 3.2Å; L765-L767 PolarHBondContact O-N 3.41Å; L767-L770 WeakPolarHBondContact O-CB 3.44Å; L767-L770 PolarHBondContact O-N 3.46Å; L767-M771 PolarHBondContact O-N 2.87Å
768R91.8Very high87.9Confident1 Ų133.7 Ų33.70%0.00417%0.169CC..Hα-helixtrans-57.9-46178.5-67-78.1-63.7170.64.1112.8T603 A614 E619 L765 L770 M771 R772T603-R768 HydrophobicContact CG2-CG 4.12Å; A614-R768 PolarHBondContact O-NH1 3.05Å; A614-R768 PolarHBondContact O-NH2 2.95Å; E619-R768 IonicContact OE1-CZ 2.98Å; E619-R768 IonicContact OE1-NH2 2.64Å; E619-R768 PolarHBondContact OE1-NH2 3.04Å; E619-R768 IonicContact OE2-CZ 3.62Å; E619-R768 VanDerWaalsContact OE2-CZ 3.28Å; E619-R768 IonicContact OE2-NE 3.02Å; E619-R768 PolarHBondContact OE2-NE 3.32Å; E619-R768 IonicContact OE2-NH2 3.04Å; E619-R768 PolarHBondContact OE2-NH2 3.32Å; L765-R768 HydrophobicContact CD2-CG 4.1Å; L765-R768 VanDerWaalsContact O-CB 3.25Å; L765-R768 WeakPolarHBondContact O-CB 3.42Å; L765-R768 VanDerWaalsContact O-CG 3.28Å; L765-R768 WeakPolarHBondContact O-CG 3.4Å; L765-R768 PolarHBondContact O-N 2.79Å; R768-L770 VanDerWaalsContact C-N 3.31Å; R768-L770 PolarHBondContact O-N 2.91Å; R768-M771 WeakPolarHBondContact O-CB 3.34Å; R768-M771 PolarHBondContact O-N 2.78Å; R768-R772 PolarHBondContact O-N 3.41Å; R768-R772 VanDerWaalsContact O-N 3.09Å
769P91.2Very high85.7Confident31 Ų3133.7 Ų33.720%0.20117%0.17CC..Hα-helixtrans-59.8-42.7176.7-23.935.6000112K766 M771 R772 I773 M783K766-P769 WeakPolarHBondContact O-CD 3.29Å; P769-M771 PolarHBondContact O-N 2.99Å; P769-R772 PolarHBondContact O-N 2.99Å; P769-I773 VanDerWaalsContact O-CG1 3.29Å; P769-I773 WeakPolarHBondContact O-CG1 3.41Å; P769-I773 PolarHBondContact O-N 2.84Å; P769-M783 HydrophobicContact CG-CE 4.26Å
770L93.1Very high83.4Confident19 Ų1939.5 Ų39.510%0.09919%0.194CC..Hα-helixtrans-62.2-43.8177.917962.2000111.6M56 R331 A334 L607 L767 R768 R772 I773 L774M56-L770 HydrophobicContact CE-CD1 4.34Å; R331-L770 HydrophobicContact CG-CD2 4.14Å; A334-L770 HydrophobicContact CB-CD1 3.4Å; A334-L770 HydrophobicContact CB-CD2 4.43Å; L607-L770 HydrophobicContact CD1-CG 4.42Å; L607-L770 HydrophobicContact CD2-CD2 4.38Å; L767-L770 WeakPolarHBondContact O-CB 3.44Å; L767-L770 PolarHBondContact O-N 3.46Å; R768-L770 VanDerWaalsContact C-N 3.31Å; R768-L770 PolarHBondContact O-N 2.91Å; L770-R772 VanDerWaalsContact C-N 3.34Å; L770-R772 PolarHBondContact O-N 3.14Å; L770-I773 PolarHBondContact O-N 2.9Å; L770-L774 HydrophobicContact CD1-CD1 3.88Å; L770-L774 HydrophobicContact CD1-CD2 4.35Å; L770-L774 HydrophobicContact CD1-CG 3.83Å; L770-L774 HydrophobicContact CG-CD1 4.03Å; L770-L774 HydrophobicContact CG-CG 4.3Å; L770-L774 WeakPolarHBondContact O-CB 3.27Å; L770-L774 WeakPolarHBondContact O-CG 3.32Å; L770-L774 PolarHBondContact O-N 2.83Å
771M93.6Very high81.4Confident3 Ų336.2 Ų36.22%0.01517%0.172CC..Hα-helixtrans-55.5-48.6175.1-175.5-156.376.700111.4A606 L607 A614 L767 R768 P769 L774 A775A606-M771 HydrophobicContact CB-CG 4.23Å; A606-M771 HydrophobicContact CB-SD 3.56Å; A606-M771 VanDerWaalsContact CB-SD 3.56Å; L607-M771 HydrophobicContact CB-CB 4.5Å; L607-M771 HydrophobicContact CB-CG 4.43Å; L607-M771 HydrophobicContact CD1-CB 4.43Å; A614-M771 HydrophobicContact CB-CE 4.26Å; A614-M771 HydrophobicContact CB-SD 3.95Å; L767-M771 PolarHBondContact O-N 2.87Å; R768-M771 WeakPolarHBondContact O-CB 3.34Å; R768-M771 PolarHBondContact O-N 2.78Å; P769-M771 PolarHBondContact O-N 2.99Å; M771-L774 PolarHBondContact O-N 2.62Å; M771-A775 VanDerWaalsContact O-CB 3.27Å; M771-A775 WeakPolarHBondContact O-CB 3.16Å; M771-A775 PolarHBondContact O-N 3.34Å
772R90.5Very high78.9Confident24 Ų2438.4 Ų38.49%0.09118%0.184CC..Hα-helixtrans-65.8-42.1179.3-67.6-174.3-173.5162.44.2112.7E619 R768 P769 L770 A775 G776 H777 S779E619-R772 IonicContact OE1-CZ 3.4Å; E619-R772 IonicContact OE1-NH2 2.71Å; E619-R772 PolarHBondContact OE1-NH2 2.65Å; E619-R772 IonicContact OE2-CZ 3.66Å; E619-R772 IonicContact OE2-NH2 3.04Å; E619-R772 PolarHBondContact OE2-NH2 3.07Å; R768-R772 PolarHBondContact O-N 3.41Å; R768-R772 VanDerWaalsContact O-N 3.09Å; P769-R772 PolarHBondContact O-N 2.99Å; L770-R772 VanDerWaalsContact C-N 3.34Å; L770-R772 PolarHBondContact O-N 3.14Å; R772-A775 PolarHBondContact O-N 3.47Å; R772-G776 PolarHBondContact O-N 3.3Å; R772-H777 PolarHBondContact O-N 3.28Å; R772-S779 PolarHBondContact NH1-O 3.06Å
773I92.5Very high76.4Confident15 Ų1539.8 Ų39.88%0.07720%0.195CC..Hα-helixtrans-57.2-55.7174.8-71.2168000109V24 M56 Y59 W86 P769 L770 A775 G776V24-I773 HydrophobicContact CB-CD1 4.24Å; M56-I773 HydrophobicContact CE-CD1 4.35Å; M56-I773 HydrophobicContact SD-CG2 3.94Å; Y59-I773 HydrophobicContact CD1-CD1 4.31Å; Y59-I773 HydrophobicContact CD1-CG1 4.24Å; Y59-I773 HydrophobicContact CD1-CG2 3.83Å; Y59-I773 HydrophobicContact CD2-CG1 4.42Å; Y59-I773 HydrophobicContact CD2-CG2 3.99Å; Y59-I773 HydrophobicContact CE1-CD1 3.89Å; Y59-I773 HydrophobicContact CE1-CG1 3.89Å; Y59-I773 HydrophobicContact CE1-CG2 4.35Å; Y59-I773 HydrophobicContact CE2-CG1 4.07Å; Y59-I773 HydrophobicContact CE2-CG2 4.48Å; Y59-I773 HydrophobicContact CG-CG1 4.5Å; Y59-I773 HydrophobicContact CG-CG2 3.64Å; W86-I773 VanDerWaalsContact CH2-O 3.27Å; W86-I773 WeakPolarHBondContact CH2-O 3.46Å; P769-I773 VanDerWaalsContact O-CG1 3.29Å; P769-I773 WeakPolarHBondContact O-CG1 3.41Å; P769-I773 PolarHBondContact O-N 2.84Å; L770-I773 PolarHBondContact O-N 2.9Å; I773-A775 PolarHBondContact O-N 2.93Å; I773-G776 PolarHBondContact O-N 3.36Å
774L93.2Very high73.4Confident2 Ų242.2 Ų42.21%0.0122%0.217CC..Hα-helixtrans-67.9-19.1-177.8-62.7-176.7000113.2R51 A52 R55 W86 L607 L770 M771R51-L774 PolarHBondContact NH2-O 2.9Å; A52-L774 HydrophobicContact CB-CD1 4.23Å; A52-L774 HydrophobicContact CB-CD2 4.2Å; R55-L774 HydrophobicContact CB-CD2 3.77Å; R55-L774 WeakPolarHBondContact CD-O 3.24Å; R55-L774 PolarHBondContact NH1-O 3.32Å; W86-L774 WeakPolarHBondContact CZ2-O 3.33Å; L607-L774 HydrophobicContact CD1-CD1 3.88Å; L770-L774 HydrophobicContact CD1-CD1 3.88Å; L770-L774 HydrophobicContact CD1-CD2 4.35Å; L770-L774 HydrophobicContact CD1-CG 3.83Å; L770-L774 HydrophobicContact CG-CD1 4.03Å; L770-L774 HydrophobicContact CG-CG 4.3Å; L770-L774 WeakPolarHBondContact O-CB 3.27Å; L770-L774 WeakPolarHBondContact O-CG 3.32Å; L770-L774 PolarHBondContact O-N 2.83Å; M771-L774 PolarHBondContact O-N 2.62Å
775A89.4Confident70.3Confident2 Ų245.6 Ų45.62%0.01725%0.246CC..Hα-helixtrans-84.4-18171.700000113.2D612 K636 M771 R772 I773 H777D612-A775 VanDerWaalsContact O-CB 3.28Å; D612-A775 WeakPolarHBondContact O-CB 3.44Å; K636-A775 PolarHBondContact NZ-O 2.86Å; M771-A775 VanDerWaalsContact O-CB 3.27Å; M771-A775 WeakPolarHBondContact O-CB 3.16Å; M771-A775 PolarHBondContact O-N 3.34Å; R772-A775 PolarHBondContact O-N 3.47Å; I773-A775 PolarHBondContact O-N 2.93Å; A775-H777 HydrophobicContact CB-CB 4.24Å
776G81.2Confident67.3Low16 Ų1648.5 Ų48.517%0.16527%0.269CS..THydrogen-bonded Turntrans65.542.6-17200000110.7W86 K636 R772 I773W86-G776 VanDerWaalsContact CZ2-N 3.33Å; K636-G776 WeakPolarHBondContact CE-O 3.41Å; K636-G776 PolarHBondContact NZ-O 3Å; R772-G776 PolarHBondContact O-N 3.3Å; I773-G776 PolarHBondContact O-N 3.36Å
777H66.2Low64.2Low9 Ų953.2 Ų53.24%0.04230%0.298CS..  trans-110.4117.5-178.2-162.745.3000109.7N613 D629 Y644 R772 A775 S779N613-H777 PolarHBondContact ND2-NE2 3.36Å; D629-H777 IonicContact OD1-CE1 2.94Å; D629-H777 PolarHBondContact OD1-CE1 2.92Å; D629-H777 IonicContact OD1-NE2 3.66Å; D629-H777 PolarHBondContact OD1-NE2 3.24Å; D629-H777 IonicContact OD2-NE2 3.84Å; Y644-H777 PolarHBondContact OH-CE1 3Å; Y644-H777 PolarHBondContact OH-ND1 3.31Å; R772-H777 PolarHBondContact O-N 3.28Å; A775-H777 HydrophobicContact CB-CB 4.24Å; H777-S779 PolarHBondContact CD2-OG 3.4Å; H777-S779 VanDerWaalsContact CD2-OG 3.25Å; H777-S779 PolarHBondContact CE1-OG 3.18Å; H777-S779 PolarHBondContact NE2-OG 3Å
778H56.3Low61Low130 Ų13056.8 Ų56.860%0.60233%0.328SS*.  trans-100.66.8-171.3-64.2-66.6000114.3F780H778-F780 WeakPolarHBondContact O-CD2 3.17Å; H778-F780 PolarHBondContact O-N 3.41Å
779S47.4Very low57.9Low10 Ų1063.3 Ų63.37%0.0736%0.363CS..  trans-71.5112.4174.5510000109.4D629 R772 H777 Y781D629-S779 PolarHBondContact OD1-OG 3.02Å; R772-S779 PolarHBondContact NH1-O 3.06Å; H777-S779 PolarHBondContact CD2-OG 3.4Å; H777-S779 VanDerWaalsContact CD2-OG 3.25Å; H777-S779 PolarHBondContact CE1-OG 3.18Å; H777-S779 PolarHBondContact NE2-OG 3Å; S779-Y781 PolarHBondContact O-N 2.84Å; S779-Y781 WeakPolarHBondContact OG-CE2 3.2Å
780F44.5Very low54.8Low135 Ų13569.3 Ų69.359%0.59240%0.399SS*.  trans-85.5104.9169-72.1-85.8000107.7H778H778-F780 WeakPolarHBondContact O-CD2 3.17Å; H778-F780 PolarHBondContact O-N 3.41Å
781Y46.4Very low51.7Low10 Ų1080.6 Ų80.64%0.03945%0.447CS..  trans-79.2120156.1-56.9-96.9000105.9E619 F621 D625 D629 S779 M783E619-Y781 WeakPolarHBondContact OE1-CD2 3.34Å; F621-Y781 HydrophobicContact CB-CD1 3.99Å; F621-Y781 HydrophobicContact CB-CE1 3.5Å; F621-Y781 VanDerWaalsContact CB-CE1 3.5Å; D625-Y781 HydrophobicContact CB-CD1 4.01Å; D625-Y781 HydrophobicContact CB-CE1 3.16Å; D629-Y781 PolarHBondContact OD2-OH 3.24Å; S779-Y781 PolarHBondContact O-N 2.84Å; S779-Y781 WeakPolarHBondContact OG-CE2 3.2Å; Y781-M783 PolarHBondContact O-N 3.42Å
782D33.8Very low49.6Very low147 Ų14784.5 Ų84.579%0.78647%0.468SS*.  trans-55.6113.5-179.1-91-34.6000110T784D782-T784 VanDerWaalsContact C-N 3.31Å; D782-T784 PolarHBondContact O-N 2.74Å
783M34.4Very low47.4Very low109 Ų10987.7 Ų87.754%0.53749%0.488SS..  trans-84.577.8167.8-75.4-155.4-69.300108.8P769 Y781 A785P769-M783 HydrophobicContact CG-CE 4.26Å; Y781-M783 PolarHBondContact O-N 3.42Å; M783-A785 PolarHBondContact O-N 2.78Å
784T26.5Very low44.9Very low112 Ų11291.7 Ų91.769%0.68751%0.511SS*.  trans-86.821.3165.341.40000112.6D782D782-T784 VanDerWaalsContact C-N 3.31Å; D782-T784 PolarHBondContact O-N 2.74Å
785A28.2Very low42.1Very low76 Ų7697 Ų9763%0.62854%0.541SS*.  trans-107.619.1-170.700000116.2M783M783-A785 PolarHBondContact O-N 2.78Å
786S28.6Very low39.1Very low101 Ų101102.9 Ų102.971%0.70657%0.573SS**SBendtrans-131.611.1174.166.70000116.4
787N27.3Very low36.3Very low163 Ų163108.7 Ų108.787%0.87260%0.601SS**SBendtrans-151.117.8172.8-89.8-27.1000114D789N787-D789 PolarHBondContact O-N 3.47Å
788A25.1Very low34.2Very low78 Ų78115.9 Ų115.965%0.64564%0.64SS**SBendtrans-91.996.8173.500000109.5
789D26.5Very low32.5Very low138 Ų138114.8 Ų114.874%0.73864%0.643SS**  trans33.793.2154.3-65.7-43.9000117.9N787 K791N787-D789 PolarHBondContact O-N 3.47Å; D789-K791 VanDerWaalsContact C-N 3.28Å; D789-K791 PolarHBondContact O-N 2.98Å
790V26.6Very low31.2Very low157 Ų157123.5 Ų123.595%0.95269%0.691SS**  trans-74.692.6138.1179.90000106
791K27.1Very low30Very low256 Ų256122.5 Ų122.5100%1.11370%0.7SS**  trans-127.70160.9-100.8-169.2177.9179.80109.2D789D789-K791 VanDerWaalsContact C-N 3.28Å; D789-K791 PolarHBondContact O-N 2.98Å

Retrieved 791 of 791 residues in 575.1 ms (Link to these results)