A0A077Z6K7_TRITR Loading...

phosphatidylinositol-3,5-bisphosphate 3-phosphatase

AlphaFold DB , UniProt , Accession A0A077Z6K7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 679 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M45.7Very low68.5Low148 Ų14886.2 Ų86.273%0.72942%0.422SS*.  0-50.70-143.9-172.9-55.200110.6E3 A4 W48 H116M1-E3 VanDerWaalsContact C-N 3.28Å; M1-E3 PolarHBondContact O-N 3.39Å; M1-A4 PolarHBondContact O-N 3.13Å; M1-A4 VanDerWaalsContact O-N 3.1Å; M1-W48 HydrophobicContact SD-CH2 4.25Å; M1-H116 WeakPolarHBondContact CE-CE1 3.5Å
2F47.6Very low70.7Confident48 Ų4888.8 Ų88.821%0.21143%0.433CS..G310 helixtrans-56-30.8179.9-159.9-100.8000116.1R7 Y31 I38F2-R7 VanDerWaalsContact CD1-NH2 3.28Å; F2-Y31 HydrophobicContact CE1-CD1 4.2Å; F2-Y31 AromaticContact CE1-CE1 3.94Å; F2-Y31 HydrophobicContact CE1-CE1 3.94Å; F2-Y31 HydrophobicContact CE1-CE2 4.36Å; F2-Y31 HydrophobicContact CE1-CG 4.5Å; F2-Y31 AromaticContact CE2-CD2 3.9Å; F2-Y31 HydrophobicContact CE2-CD2 3.9Å; F2-Y31 HydrophobicContact CE2-CE2 4.22Å; F2-Y31 HydrophobicContact CE2-CG 4.03Å; F2-Y31 AromaticContact CZ-CD1 3.53Å; F2-Y31 HydrophobicContact CZ-CD1 3.53Å; F2-Y31 AromaticContact CZ-CD2 3.45Å; F2-Y31 HydrophobicContact CZ-CD2 3.45Å; F2-Y31 VanDerWaalsContact CZ-CD2 3.45Å; F2-Y31 AromaticContact CZ-CE1 3.59Å; F2-Y31 HydrophobicContact CZ-CE1 3.59Å; F2-Y31 AromaticContact CZ-CE2 3.51Å; F2-Y31 HydrophobicContact CZ-CE2 3.51Å; F2-Y31 AromaticContact CZ-CG 3.44Å; F2-Y31 HydrophobicContact CZ-CG 3.44Å; F2-Y31 VanDerWaalsContact CZ-CG 3.44Å; F2-Y31 AromaticContact CZ-CZ 3.57Å; F2-I38 HydrophobicContact CD2-CD1 4.07Å; F2-I38 HydrophobicContact CE2-CB 4.47Å; F2-I38 HydrophobicContact CE2-CD1 3.92Å; F2-I38 HydrophobicContact CE2-CG2 4.15Å
3E48.7Very low72.4Confident188 Ų18888 Ų8888%0.87943%0.432SS*.G310 helixtrans-76.2-19.2178.2-66.6178.3166.200114.1M1M1-E3 VanDerWaalsContact C-N 3.28Å; M1-E3 PolarHBondContact O-N 3.39Å
4A55.8Low74.1Confident92 Ų9281.7 Ų81.776%0.7640%0.401SS*.G310 helixtrans-90.2-7.1-177.500000113.5M1M1-A4 PolarHBondContact O-N 3.13Å; M1-A4 VanDerWaalsContact O-N 3.1Å
5L61Low75.4Confident34 Ų3477.8 Ų77.818%0.17838%0.383CS..SBendtrans-91.4127.8-176.1-68.2169.8000110.4R7 T33 N34 I38 W48L5-R7 PolarHBondContact O-N 3.13Å; L5-T33 HydrophobicContact CB-CG2 3.89Å; L5-T33 HydrophobicContact CD1-CG2 3.96Å; L5-T33 HydrophobicContact CG-CG2 4.48Å; L5-N34 WeakPolarHBondContact CD2-OD1 3.41Å; L5-I38 HydrophobicContact CD1-CD1 4.02Å; L5-W48 HydrophobicContact CD1-CH2 4.02Å; L5-W48 HydrophobicContact CD1-CZ3 4.06Å
6H72.6Confident76.4Confident120 Ų12075.5 Ų75.556%0.55637%0.369SS*.PPolyproline II helixtrans-64.4127.1170.8-174.370.6000109.6Y8 T33 N34H6-Y8 AromaticContact CD2-CE2 3.74Å; H6-Y8 AromaticContact CD2-CZ 3.7Å; H6-T33 CarbonylContact O-C 3.59Å; H6-T33 VanDerWaalsContact O-CA 3.23Å; H6-T33 WeakPolarHBondContact O-CA 3.27Å; H6-N34 PolarHBondContact O-N 2.99Å
7R73.1Confident77.1Confident104 Ų10474.4 Ų74.439%0.39236%0.36SS..EExtended strand (participates in β ladder)trans-100.5119.6-177.3-59.7-177.5-171.1171.38.4109.7F2 L5F2-R7 VanDerWaalsContact CD1-NH2 3.28Å; L5-R7 PolarHBondContact O-N 3.13Å
8Y78.8Confident77.3Confident117 Ų11772.2 Ų72.246%0.45935%0.351SS..EExtended strand (participates in β ladder)trans-85.8-36.6174-67.4-91.1000111.6H6 L32 T33 N34 L99H6-Y8 AromaticContact CD2-CE2 3.74Å; H6-Y8 AromaticContact CD2-CZ 3.7Å; Y8-L32 PolarHBondContact N-O 3.28Å; Y8-T33 WeakPolarHBondContact CD2-O 3.49Å; Y8-N34 VanDerWaalsContact CE2-CA 3.47Å; Y8-N34 HydrophobicContact CE2-CB 3.8Å; Y8-L99 HydrophobicContact CD2-CD1 4.3Å
9C85Confident76.9Confident10 Ų1073.6 Ų73.67%0.06836%0.357CS..EExtended strand (participates in β ladder)trans-149.8140.9-175.4-171.50000109.9L32C9-L32 HydrophobicContact CB-CB 3.95Å; C9-L32 HydrophobicContact CB-CD1 3.88Å; C9-L32 HydrophobicContact CB-CG 3.98Å; C9-L32 PolarHBondContact N-O 3.44Å; C9-L32 PolarHBondContact O-N 2.88Å
10Q92Very high76.5Confident84 Ų8473 Ų7339%0.39336%0.36SS..EExtended strand (participates in β ladder)trans-133.3119.8170.5173.3178.2-34.300107.6E12 T29 L30 Y31Q10-E12 PolarHBondContact NE2-OE1 3.13Å; Q10-T29 HydrophobicContact CG-CG2 3.82Å; Q10-L30 WeakPolarHBondContact CA-O 3.46Å; Q10-Y31 HydrophobicContact CB-CD1 4.19Å; Q10-Y31 HydrophobicContact CB-CE1 4.44Å; Q10-Y31 HydrophobicContact CG-CD1 3.91Å; Q10-Y31 HydrophobicContact CG-CE1 3.71Å
11V93.7Very high76.3Confident3 Ų371 Ų712%0.01835%0.351CS..EExtended strand (participates in β ladder)trans-123.3119.5177.8-173.60000108.7V14 T29 L30 V83 D88 V92V11-V14 HydrophobicContact CB-CG2 3.85Å; V11-V14 HydrophobicContact CG1-CG2 3.58Å; V11-V14 WeakPolarHBondContact O-CG2 3.36Å; V11-T29 WeakPolarHBondContact O-CA 3.45Å; V11-L30 HydrophobicContact CB-CB 4.47Å; V11-L30 PolarHBondContact N-O 3Å; V11-L30 PolarHBondContact O-N 3.48Å; V11-V83 HydrophobicContact CG1-CG1 4Å; V11-D88 HydrophobicContact CG1-CB 4.01Å; V11-D88 HydrophobicContact CG2-CB 4.07Å; V11-V92 HydrophobicContact CG2-CG2 3.63Å
12E93.9Very high77.7Confident118 Ų11867.7 Ų67.755%0.55135%0.347SS*.EExtended strand (participates in β ladder)trans-87.5160.6179.3-64.2-172.6177.800111.7Q10 V14 T29Q10-E12 PolarHBondContact NE2-OE1 3.13Å; E12-V14 PolarHBondContact O-N 3.1Å; E12-T29 HydrophobicContact CG-CG2 3.99Å
13N93.8Very high79.1Confident78 Ų7874.1 Ų74.142%0.41738%0.378SS..EExtended strand (participates in β ladder)trans56.930.7178.3-56.5-59.2000114.1T27 G28 K42N13-T27 HydrophobicContact CB-CG2 4.49Å; N13-G28 WeakPolarHBondContact CA-O 3.45Å; N13-G28 PolarHBondContact N-O 2.88Å; N13-G28 VanDerWaalsContact N-O 3.1Å; N13-K42 PolarHBondContact OD1-NZ 3.16Å; N13-K42 VanDerWaalsContact OD1-NZ 3.13Å
14V95.7Very high80.6Confident0 Ų067.3 Ų67.30%035%0.348CS..EExtended strand (participates in β ladder)trans-73.1137.4169.8178.20000108.7V11 E12 T27 G28 L30 F39 L81 V83V11-V14 HydrophobicContact CB-CG2 3.85Å; V11-V14 HydrophobicContact CG1-CG2 3.58Å; V11-V14 WeakPolarHBondContact O-CG2 3.36Å; E12-V14 PolarHBondContact O-N 3.1Å; V14-T27 CarbonylContact O-C 3.56Å; V14-T27 WeakPolarHBondContact O-CA 3.49Å; V14-G28 PolarHBondContact N-O 3.49Å; V14-G28 PolarHBondContact O-N 3.41Å; V14-L30 HydrophobicContact CB-CB 4.27Å; V14-L30 HydrophobicContact CG1-CB 4.47Å; V14-L30 HydrophobicContact CG2-CB 3.83Å; V14-F39 HydrophobicContact CB-CE2 4.28Å; V14-F39 HydrophobicContact CG1-CE2 4.3Å; V14-F39 WeakPolarHBondContact O-CE2 3.46Å; V14-L81 HydrophobicContact CG1-CB 3.95Å; V14-L81 HydrophobicContact CG1-CD2 4.05Å; V14-L81 HydrophobicContact CG1-CG 4.4Å; V14-V83 HydrophobicContact CG1-CG2 4.38Å; V14-V83 HydrophobicContact CG2-CG2 4.28Å
15V93.9Very high82Confident23 Ų2365.4 Ų65.414%0.13933%0.325CS..EExtended strand (participates in β ladder)trans-102115.5174.6-176.70000108.9Y17 N25 R26 L81 L82V15-Y17 PolarHBondContact O-N 3.35Å; V15-Y17 VanDerWaalsContact O-N 3.15Å; V15-N25 HydrophobicContact CG1-CB 4.29Å; V15-R26 CarbonylContact C-O 3.58Å; V15-R26 WeakPolarHBondContact CA-O 3.32Å; V15-L81 CarbonylContact O-C 3.6Å; V15-L81 WeakPolarHBondContact O-CA 3.4Å; V15-L82 HydrophobicContact CB-CB 4.15Å; V15-L82 PolarHBondContact N-O 2.91Å; V15-L82 PolarHBondContact O-N 3.1Å
16W91.2Very high83.4Confident41 Ų4165.8 Ų65.816%0.15532%0.324CS..EExtended strand (participates in β ladder)trans-68.5108.4158174.812.6000107.5N25 R26 F39 L47 L79 L81 W625W16-N25 WeakPolarHBondContact O-CA 3.37Å; W16-R26 PolarHBondContact N-O 3.45Å; W16-R26 PolarHBondContact O-N 3.27Å; W16-F39 HydrophobicContact CB-CD1 4.22Å; W16-F39 HydrophobicContact CB-CE1 3.7Å; W16-F39 HydrophobicContact CB-CE2 4.32Å; W16-F39 HydrophobicContact CB-CZ 3.78Å; W16-F39 HydrophobicContact CE3-CD1 4.21Å; W16-F39 HydrophobicContact CE3-CE1 4.14Å; W16-L47 HydrophobicContact CH2-CD2 4.46Å; W16-L47 HydrophobicContact CZ3-CD2 4.42Å; W16-L79 HydrophobicContact CD2-CD1 4.04Å; W16-L79 HydrophobicContact CG-CD1 3.72Å; W16-L81 HydrophobicContact CB-CD2 4.31Å; W16-W625 HydrophobicContact CH2-CZ3 4.41Å; W16-W625 HydrophobicContact CZ3-CH2 4.35Å
17Y87.6Confident84.4Confident56 Ų5662.6 Ų62.622%0.2231%0.313CS..EExtended strand (participates in β ladder)trans-96.3120.9-175.3-174.8-109.7000111V15 Q19 N25 T80 L82V15-Y17 PolarHBondContact O-N 3.35Å; V15-Y17 VanDerWaalsContact O-N 3.15Å; Y17-Q19 HydrophobicContact CD1-CG 3.83Å; Y17-Q19 HydrophobicContact CE1-CB 4.16Å; Y17-Q19 HydrophobicContact CE1-CG 3.74Å; Y17-N25 WeakPolarHBondContact CA-OD1 3.27Å; Y17-T80 HydrophobicContact CD1-CG2 4.06Å; Y17-T80 PolarHBondContact N-O 2.96Å; Y17-T80 WeakPolarHBondContact O-CB 3.49Å; Y17-L82 HydrophobicContact CD2-CD1 3.74Å; Y17-L82 HydrophobicContact CE2-CD1 4.4Å; Y17-L82 HydrophobicContact CG-CD1 3.86Å; Y17-L82 HydrophobicContact CG-CG 4.18Å
18D81.2Confident85.5Confident36 Ų3657.7 Ų57.719%0.19330%0.295CS..  trans-93.7112.9166.8-174.5-38.9000108C20 V21 N24 N25D18-C20 PolarHBondContact O-N 3.1Å; D18-C20 WeakPolarHBondContact OD1-CA 3.34Å; D18-C20 WeakPolarHBondContact OD1-CB 3.41Å; D18-C20 PolarHBondContact OD1-N 3.03Å; D18-V21 WeakPolarHBondContact CB-O 3.43Å; D18-V21 PolarHBondContact OD1-N 2.71Å; D18-N24 HydrophobicContact CB-CB 3.66Å; D18-N24 VanDerWaalsContact OD2-CB 3.26Å; D18-N24 WeakPolarHBondContact OD2-CB 3.23Å; D18-N24 PolarHBondContact OD2-ND2 2.93Å; D18-N25 PolarHBondContact N-OD1 2.78Å; D18-N25 PolarHBondContact O-OD1 3.26Å
19Q70.9Confident86.3Confident99 Ų9953.3 Ų53.346%0.46328%0.28SS..SBendtrans-69.7-15.1-177.6-53-169.26.900113.3Y17 T80Y17-Q19 HydrophobicContact CD1-CG 3.83Å; Y17-Q19 HydrophobicContact CE1-CB 4.16Å; Y17-Q19 HydrophobicContact CE1-CG 3.74Å; Q19-T80 PolarHBondContact NE2-OG1 3.34Å
20C68.6Low86.8Confident61 Ų6152.9 Ų52.941%0.41228%0.277SS..SBendtrans-106-32.4-171-70.30000112.7D18 K293D18-C20 PolarHBondContact O-N 3.1Å; D18-C20 WeakPolarHBondContact OD1-CA 3.34Å; D18-C20 WeakPolarHBondContact OD1-CB 3.41Å; D18-C20 PolarHBondContact OD1-N 3.03Å; C20-K293 HydrophobicContact CB-CD 3.94Å; C20-K293 HydrophobicContact CB-CG 4.04Å
21V71.7Confident87Confident31 Ų3150.5 Ų50.519%0.18827%0.265CS..  trans-135.6103.7-178.3-177.40000109.2D18 E23 N24D18-V21 WeakPolarHBondContact CB-O 3.43Å; D18-V21 PolarHBondContact OD1-N 2.71Å; V21-E23 HydrophobicContact CG1-CB 3.96Å; V21-E23 PolarHBondContact O-N 3.15Å; V21-E23 VanDerWaalsContact O-N 3.13Å; V21-N24 HydrophobicContact CB-CB 4.2Å; V21-N24 HydrophobicContact CG1-CB 4.33Å; V21-N24 WeakPolarHBondContact O-CB 3.4Å; V21-N24 PolarHBondContact O-N 3.36Å
22A75.5Confident87Confident78 Ų7850.4 Ų50.465%0.64527%0.265SS*.G310 helixtrans-58.1-30.6-179.900000113N24 N25A22-N24 PolarHBondContact O-N 2.91Å; A22-N25 VanDerWaalsContact O-CB 3.24Å; A22-N25 WeakPolarHBondContact O-CB 3.46Å; A22-N25 VanDerWaalsContact O-CG 3.24Å; A22-N25 PolarHBondContact O-N 3.41Å; A22-N25 VanDerWaalsContact O-N 3.14Å; A22-N25 PolarHBondContact O-ND2 2.78Å
23E77.1Confident86.8Confident183 Ų18344.9 Ų44.986%0.85524%0.239SC*.G310 helixtrans-66.8-20.1177.2-62.2163.3-175.900113.2V21 N25V21-E23 HydrophobicContact CG1-CB 3.96Å; V21-E23 PolarHBondContact O-N 3.15Å; V21-E23 VanDerWaalsContact O-N 3.13Å; E23-N25 VanDerWaalsContact C-N 3.31Å
24N78.8Confident86.3Confident45 Ų4544.8 Ų44.824%0.24124%0.238CC..G310 helixtrans-82.6-9.4175.5-73.8-15.1000112.8D18 V21 A22 R26D18-N24 HydrophobicContact CB-CB 3.66Å; D18-N24 VanDerWaalsContact OD2-CB 3.26Å; D18-N24 WeakPolarHBondContact OD2-CB 3.23Å; D18-N24 PolarHBondContact OD2-ND2 2.93Å; V21-N24 HydrophobicContact CB-CB 4.2Å; V21-N24 HydrophobicContact CG1-CB 4.33Å; V21-N24 WeakPolarHBondContact O-CB 3.4Å; V21-N24 PolarHBondContact O-N 3.36Å; A22-N24 PolarHBondContact O-N 2.91Å; N24-R26 WeakPolarHBondContact O-CG 3.38Å; N24-R26 PolarHBondContact O-N 3.4Å
25N86.7Confident85.8Confident53 Ų5347 Ų4728%0.28325%0.252SS..  trans-61.3131.8179.5-69.5-21.3000110.4V15 W16 Y17 D18 A22 E23V15-N25 HydrophobicContact CG1-CB 4.29Å; W16-N25 WeakPolarHBondContact O-CA 3.37Å; Y17-N25 WeakPolarHBondContact CA-OD1 3.27Å; D18-N25 PolarHBondContact N-OD1 2.78Å; D18-N25 PolarHBondContact O-OD1 3.26Å; A22-N25 VanDerWaalsContact O-CB 3.24Å; A22-N25 WeakPolarHBondContact O-CB 3.46Å; A22-N25 VanDerWaalsContact O-CG 3.24Å; A22-N25 PolarHBondContact O-N 3.41Å; A22-N25 VanDerWaalsContact O-N 3.14Å; A22-N25 PolarHBondContact O-ND2 2.78Å; E23-N25 VanDerWaalsContact C-N 3.31Å
26R89.5Confident85.7Confident41 Ų4148.4 Ų48.416%0.15526%0.257CS..EExtended strand (participates in β ladder)trans-124129.2177.9-61.2-172.2-171.5161.27.1109.8V15 W16 N24 F39 W625V15-R26 CarbonylContact C-O 3.58Å; V15-R26 WeakPolarHBondContact CA-O 3.32Å; W16-R26 PolarHBondContact N-O 3.45Å; W16-R26 PolarHBondContact O-N 3.27Å; N24-R26 WeakPolarHBondContact O-CG 3.38Å; N24-R26 PolarHBondContact O-N 3.4Å; R26-F39 HydrophobicContact CB-CE1 4.08Å; R26-F39 HydrophobicContact CB-CZ 4.31Å; R26-F39 VanDerWaalsContact O-CZ 3.3Å; R26-F39 WeakPolarHBondContact O-CZ 3.42Å; R26-W625 VanDerWaalsContact NH1-CH2 3.34Å
27T94.2Very high85.9Confident53 Ų5346.5 Ų46.533%0.32525%0.249SC..EExtended strand (participates in β ladder)trans-89.7140167.5-50.30000109.3N13 V14 K42N13-T27 HydrophobicContact CB-CG2 4.49Å; V14-T27 CarbonylContact O-C 3.56Å; V14-T27 WeakPolarHBondContact O-CA 3.49Å; T27-K42 HydrophobicContact CG2-CD 4.38Å; T27-K42 WeakPolarHBondContact O-CG 3.4Å; T27-K42 PolarHBondContact O-N 3.23Å
28G95.2Very high86.1Confident1 Ų143.8 Ų43.81%0.0124%0.239CC..EExtended strand (participates in β ladder)trans-163.6-167.1-176.900000112.8N13 V14 A40N13-G28 WeakPolarHBondContact CA-O 3.45Å; N13-G28 PolarHBondContact N-O 2.88Å; N13-G28 VanDerWaalsContact N-O 3.1Å; V14-G28 PolarHBondContact N-O 3.49Å; V14-G28 PolarHBondContact O-N 3.41Å; G28-A40 CarbonylContact C-O 3.57Å; G28-A40 WeakPolarHBondContact CA-O 3.3Å
29T96.1Very high86.7Confident26 Ų2642.2 Ų42.216%0.1623%0.23CC..EExtended strand (participates in β ladder)trans-111.5131.5173.5-55.40000109Q10 V11 E12 Y31 A40Q10-T29 HydrophobicContact CG-CG2 3.82Å; V11-T29 WeakPolarHBondContact O-CA 3.45Å; E12-T29 HydrophobicContact CG-CG2 3.99Å; T29-Y31 HydrophobicContact CG2-CD1 4.34Å; T29-Y31 HydrophobicContact CG2-CD2 4.17Å; T29-Y31 HydrophobicContact CG2-CE1 3.74Å; T29-Y31 HydrophobicContact CG2-CE2 3.54Å; T29-Y31 WeakPolarHBondContact CG2-OH 3.08Å; T29-A40 PolarHBondContact N-O 3.12Å; T29-A40 PolarHBondContact O-N 3.27Å
30L96.2Very high87.8Confident1 Ų138.5 Ų38.51%0.00522%0.216CC..EExtended strand (participates in β ladder)trans-94.1131.1174.2-174.571000109.3Q10 V11 V14 L32 L37 F39 L81 V92Q10-L30 WeakPolarHBondContact CA-O 3.46Å; V11-L30 HydrophobicContact CB-CB 4.47Å; V11-L30 PolarHBondContact N-O 3Å; V11-L30 PolarHBondContact O-N 3.48Å; V14-L30 HydrophobicContact CB-CB 4.27Å; V14-L30 HydrophobicContact CG1-CB 4.47Å; V14-L30 HydrophobicContact CG2-CB 3.83Å; L30-L32 HydrophobicContact CD2-CD2 4.47Å; L30-L32 HydrophobicContact CG-CD2 4.4Å; L30-L37 HydrophobicContact CD1-CD1 3.86Å; L30-L37 HydrophobicContact CD1-CD2 3.79Å; L30-L37 HydrophobicContact CD1-CG 3.66Å; L30-F39 HydrophobicContact CD1-CB 4.34Å; L30-L81 HydrophobicContact CD1-CD1 3.83Å; L30-L81 HydrophobicContact CD2-CD1 3.97Å; L30-V92 HydrophobicContact CD2-CG1 3.74Å; L30-V92 HydrophobicContact CD2-CG2 3.94Å
31Y94.8Very high88.8Confident34 Ų3436 Ų3613%0.13320%0.2CC..EExtended strand (participates in β ladder)trans-123.5126.4175.6-55.3-90.1000109.5F2 Q10 T29 I38 A40F2-Y31 HydrophobicContact CE1-CD1 4.2Å; F2-Y31 AromaticContact CE1-CE1 3.94Å; F2-Y31 HydrophobicContact CE1-CE1 3.94Å; F2-Y31 HydrophobicContact CE1-CE2 4.36Å; F2-Y31 HydrophobicContact CE1-CG 4.5Å; F2-Y31 AromaticContact CE2-CD2 3.9Å; F2-Y31 HydrophobicContact CE2-CD2 3.9Å; F2-Y31 HydrophobicContact CE2-CE2 4.22Å; F2-Y31 HydrophobicContact CE2-CG 4.03Å; F2-Y31 AromaticContact CZ-CD1 3.53Å; F2-Y31 HydrophobicContact CZ-CD1 3.53Å; F2-Y31 AromaticContact CZ-CD2 3.45Å; F2-Y31 HydrophobicContact CZ-CD2 3.45Å; F2-Y31 VanDerWaalsContact CZ-CD2 3.45Å; F2-Y31 AromaticContact CZ-CE1 3.59Å; F2-Y31 HydrophobicContact CZ-CE1 3.59Å; F2-Y31 AromaticContact CZ-CE2 3.51Å; F2-Y31 HydrophobicContact CZ-CE2 3.51Å; F2-Y31 AromaticContact CZ-CG 3.44Å; F2-Y31 HydrophobicContact CZ-CG 3.44Å; F2-Y31 VanDerWaalsContact CZ-CG 3.44Å; F2-Y31 AromaticContact CZ-CZ 3.57Å; Q10-Y31 HydrophobicContact CB-CD1 4.19Å; Q10-Y31 HydrophobicContact CB-CE1 4.44Å; Q10-Y31 HydrophobicContact CG-CD1 3.91Å; Q10-Y31 HydrophobicContact CG-CE1 3.71Å; T29-Y31 HydrophobicContact CG2-CD1 4.34Å; T29-Y31 HydrophobicContact CG2-CD2 4.17Å; T29-Y31 HydrophobicContact CG2-CE1 3.74Å; T29-Y31 HydrophobicContact CG2-CE2 3.54Å; T29-Y31 WeakPolarHBondContact CG2-OH 3.08Å; Y31-I38 PolarHBondContact N-O 2.99Å; Y31-I38 PolarHBondContact O-N 3.16Å; Y31-A40 HydrophobicContact CE2-CB 3.96Å
32L93.7Very high89.6Confident1 Ų141.9 Ų41.91%0.00522%0.223CC..EExtended strand (participates in β ladder)trans-102.4111.6170.1-55.4-173.2000108.2Y8 C9 L30 L37 Y51 V92 T95 L96Y8-L32 PolarHBondContact N-O 3.28Å; C9-L32 HydrophobicContact CB-CB 3.95Å; C9-L32 HydrophobicContact CB-CD1 3.88Å; C9-L32 HydrophobicContact CB-CG 3.98Å; C9-L32 PolarHBondContact N-O 3.44Å; C9-L32 PolarHBondContact O-N 2.88Å; L30-L32 HydrophobicContact CD2-CD2 4.47Å; L30-L32 HydrophobicContact CG-CD2 4.4Å; L32-L37 HydrophobicContact CD2-CB 4.01Å; L32-L37 HydrophobicContact CD2-CD1 3.95Å; L32-L37 HydrophobicContact CD2-CG 3.92Å; L32-Y51 WeakPolarHBondContact CA-OH 3.3Å; L32-V92 HydrophobicContact CD1-CB 4.41Å; L32-V92 HydrophobicContact CD1-CG1 4.23Å; L32-V92 HydrophobicContact CD1-CG2 4.37Å; L32-T95 HydrophobicContact CB-CG2 4.17Å; L32-T95 HydrophobicContact CD1-CG2 3.54Å; L32-L96 HydrophobicContact CD1-CD2 4.46Å; L32-L96 HydrophobicContact CD1-CG 4.22Å; L32-L96 HydrophobicContact CD2-CD2 3.77Å; L32-L96 HydrophobicContact CD2-CG 4.25Å
33T91Very high89.9Confident2 Ų242.6 Ų42.61%0.01222%0.216CC..EExtended strand (participates in β ladder)trans-99-172.1178.670.30000110.9L5 H6 Y8 T35 H36 I38 Y51L5-T33 HydrophobicContact CB-CG2 3.89Å; L5-T33 HydrophobicContact CD1-CG2 3.96Å; L5-T33 HydrophobicContact CG-CG2 4.48Å; H6-T33 CarbonylContact O-C 3.59Å; H6-T33 VanDerWaalsContact O-CA 3.23Å; H6-T33 WeakPolarHBondContact O-CA 3.27Å; Y8-T33 WeakPolarHBondContact CD2-O 3.49Å; T33-T35 VanDerWaalsContact C-N 3.29Å; T33-T35 PolarHBondContact OG1-N 3.47Å; T33-H36 PolarHBondContact N-O 3.47Å; T33-H36 PolarHBondContact OG1-N 2.64Å; T33-H36 PolarHBondContact OG1-O 2.85Å; T33-I38 HydrophobicContact CG2-CD1 3.84Å; T33-Y51 PolarHBondContact N-OH 3.32Å; T33-Y51 WeakPolarHBondContact O-CE2 3.15Å; T33-Y51 VanDerWaalsContact O-CZ 3.29Å; T33-Y51 PolarHBondContact O-OH 3.47Å
34N83.6Confident90Very high76 Ų7637.1 Ų37.141%0.40621%0.208SC..SBendtrans-73.1-17.3172.763.2-25.3000114.6L5 H6 Y8L5-N34 WeakPolarHBondContact CD2-OD1 3.41Å; H6-N34 PolarHBondContact O-N 2.99Å; Y8-N34 VanDerWaalsContact CE2-CA 3.47Å; Y8-N34 HydrophobicContact CE2-CB 3.8Å
35T84.8Confident90Very high45 Ų4538.1 Ų38.128%0.27621%0.21SC..SBendtrans-126-30.8-173.650.90000113.5T33 Y51T33-T35 VanDerWaalsContact C-N 3.29Å; T33-T35 PolarHBondContact OG1-N 3.47Å; T35-Y51 VanDerWaalsContact C-CD2 3.44Å; T35-Y51 VanDerWaalsContact C-CE2 3.45Å; T35-Y51 VanDerWaalsContact O-CD2 3.32Å; T35-Y51 WeakPolarHBondContact O-CD2 3.4Å; T35-Y51 PolarHBondContact O-N 3.46Å
36H91.6Very high90Very high54 Ų5439.9 Ų39.925%0.2522%0.217CC..EExtended strand (participates in β ladder)trans-138145-172.2-61.578.2000112.4T33 I38 W48 I49 A50 Y51T33-H36 PolarHBondContact N-O 3.47Å; T33-H36 PolarHBondContact OG1-N 2.64Å; T33-H36 PolarHBondContact OG1-O 2.85Å; H36-I38 HydrophobicContact CB-CG1 4.05Å; H36-W48 HydrophobicContact CB-CE3 4.17Å; H36-W48 AromaticContact CG-CE3 3.95Å; H36-I49 CarbonylContact C-O 3.57Å; H36-I49 VanDerWaalsContact CA-O 3.3Å; H36-I49 WeakPolarHBondContact CA-O 3.4Å; H36-A50 PolarHBondContact CD2-N 3.43Å; H36-Y51 VanDerWaalsContact C-CZ 3.44Å; H36-Y51 PolarHBondContact O-OH 2.86Å
37L94.3Very high89.8Confident0 Ų039.8 Ų39.80%022%0.219CC..EExtended strand (participates in β ladder)trans-75.7130.3150.4175155.7000107.9L30 L32 I49 Y51 I71 L79 L81 L96L30-L37 HydrophobicContact CD1-CD1 3.86Å; L30-L37 HydrophobicContact CD1-CD2 3.79Å; L30-L37 HydrophobicContact CD1-CG 3.66Å; L32-L37 HydrophobicContact CD2-CB 4.01Å; L32-L37 HydrophobicContact CD2-CD1 3.95Å; L32-L37 HydrophobicContact CD2-CG 3.92Å; L37-I49 HydrophobicContact CB-CB 4.41Å; L37-I49 HydrophobicContact CD2-CB 4.42Å; L37-I49 HydrophobicContact CD2-CD1 4.3Å; L37-I49 PolarHBondContact N-O 2.85Å; L37-I49 PolarHBondContact O-N 2.71Å; L37-Y51 HydrophobicContact CB-CE1 4.08Å; L37-I71 HydrophobicContact CD1-CD1 3.44Å; L37-I71 VanDerWaalsContact CD1-CD1 3.44Å; L37-L79 HydrophobicContact CD2-CD2 4.17Å; L37-L81 HydrophobicContact CD1-CD1 4.36Å; L37-L96 HydrophobicContact CB-CD2 4.31Å; L37-L96 HydrophobicContact CD1-CD1 4.1Å; L37-L96 HydrophobicContact CD1-CD2 3.83Å
38I93.6Very high89.6Confident0 Ų041.4 Ų41.40%022%0.22CC..EExtended strand (participates in β ladder)trans-124.5121.4176.3-53.6170.3000108.2F2 L5 Y31 T33 H36 L47 W48F2-I38 HydrophobicContact CD2-CD1 4.07Å; F2-I38 HydrophobicContact CE2-CB 4.47Å; F2-I38 HydrophobicContact CE2-CD1 3.92Å; F2-I38 HydrophobicContact CE2-CG2 4.15Å; L5-I38 HydrophobicContact CD1-CD1 4.02Å; Y31-I38 PolarHBondContact N-O 2.99Å; Y31-I38 PolarHBondContact O-N 3.16Å; T33-I38 HydrophobicContact CG2-CD1 3.84Å; H36-I38 HydrophobicContact CB-CG1 4.05Å; I38-L47 CarbonylContact C-O 3.54Å; I38-L47 VanDerWaalsContact CA-O 3.31Å; I38-L47 WeakPolarHBondContact CA-O 3.48Å; I38-W48 HydrophobicContact CD1-CD2 3.99Å; I38-W48 HydrophobicContact CD1-CE3 3.85Å; I38-W48 HydrophobicContact CD1-CH2 3.6Å; I38-W48 HydrophobicContact CD1-CZ2 3.74Å; I38-W48 HydrophobicContact CD1-CZ3 3.66Å; I38-W48 HydrophobicContact CG1-CD2 3.84Å; I38-W48 HydrophobicContact CG1-CE3 3.95Å; I38-W48 HydrophobicContact CG1-CG 4.29Å; I38-W48 HydrophobicContact CG1-CZ2 4.42Å; I38-W48 HydrophobicContact CG1-CZ3 4.29Å; I38-W48 HydrophobicContact CG2-CD2 4.43Å; I38-W48 HydrophobicContact CG2-CG 4.48Å
39F93.7Very high89.3Confident2 Ų241.9 Ų41.91%0.00922%0.222CC..EExtended strand (participates in β ladder)trans-106113.7169.4174.9-97.4000109.1V14 W16 R26 L30 E46 L47 L81V14-F39 HydrophobicContact CB-CE2 4.28Å; V14-F39 HydrophobicContact CG1-CE2 4.3Å; V14-F39 WeakPolarHBondContact O-CE2 3.46Å; W16-F39 HydrophobicContact CB-CD1 4.22Å; W16-F39 HydrophobicContact CB-CE1 3.7Å; W16-F39 HydrophobicContact CB-CE2 4.32Å; W16-F39 HydrophobicContact CB-CZ 3.78Å; W16-F39 HydrophobicContact CE3-CD1 4.21Å; W16-F39 HydrophobicContact CE3-CE1 4.14Å; R26-F39 HydrophobicContact CB-CE1 4.08Å; R26-F39 HydrophobicContact CB-CZ 4.31Å; R26-F39 VanDerWaalsContact O-CZ 3.3Å; R26-F39 WeakPolarHBondContact O-CZ 3.42Å; L30-F39 HydrophobicContact CD1-CB 4.34Å; F39-E46 CarbonylContact O-C 3.55Å; F39-E46 WeakPolarHBondContact O-CA 3.29Å; F39-L47 HydrophobicContact CB-CB 4.32Å; F39-L47 PolarHBondContact N-O 3.37Å; F39-L47 PolarHBondContact O-N 2.99Å; F39-L81 HydrophobicContact CD2-CD2 4.46Å
40A92.6Very high89Confident21 Ų2141.7 Ų41.717%0.17422%0.223CC..EExtended strand (participates in β ladder)trans-103.1109.3177.100000109.6G28 T29 Y31 K45 E46G28-A40 CarbonylContact C-O 3.57Å; G28-A40 WeakPolarHBondContact CA-O 3.3Å; T29-A40 PolarHBondContact N-O 3.12Å; T29-A40 PolarHBondContact O-N 3.27Å; Y31-A40 HydrophobicContact CE2-CB 3.96Å; A40-K45 CarbonylContact C-O 3.56Å; A40-K45 WeakPolarHBondContact CA-O 3.18Å; A40-E46 HydrophobicContact CB-CG 4.25Å
41S90.2Very high88.8Confident9 Ų942.1 Ų42.16%0.06322%0.224CC..EExtended strand (participates in β ladder)trans-77.115517946.90000112.4D43 G44 K45S41-D43 WeakPolarHBondContact CB-OD1 3.39Å; S41-D43 PolarHBondContact O-N 3.36Å; S41-D43 VanDerWaalsContact O-N 3.1Å; S41-D43 PolarHBondContact OG-OD1 3.02Å; S41-G44 PolarHBondContact O-N 2.68Å; S41-K45 PolarHBondContact N-O 2.94Å; S41-K45 WeakPolarHBondContact OG-CB 3.33Å; S41-K45 PolarHBondContact OG-N 3.15Å; S41-K45 PolarHBondContact OG-O 3.39Å
42K88.9Confident88.6Confident154 Ų15440.9 Ų40.967%0.6722%0.221SC*.THydrogen-bonded Turntrans-60.5-19.2178.9-71.3-179.7-179.8178.50114N13 T27 G44N13-K42 PolarHBondContact OD1-NZ 3.16Å; N13-K42 VanDerWaalsContact OD1-NZ 3.13Å; T27-K42 HydrophobicContact CG2-CD 4.38Å; T27-K42 WeakPolarHBondContact O-CG 3.4Å; T27-K42 PolarHBondContact O-N 3.23Å; K42-G44 VanDerWaalsContact C-N 3.28Å
43D82Confident88.4Confident94 Ų9441.8 Ų41.850%0.50323%0.225SC..THydrogen-bonded Turntrans-84.75.6173.871.3-17.8000113.9S41 K45S41-D43 WeakPolarHBondContact CB-OD1 3.39Å; S41-D43 PolarHBondContact O-N 3.36Å; S41-D43 VanDerWaalsContact O-N 3.1Å; S41-D43 PolarHBondContact OG-OD1 3.02Å; D43-K45 PolarHBondContact OD1-N 2.73Å
44G79.4Confident88.5Confident67 Ų6741.8 Ų41.869%0.69123%0.225SC*.SBendtrans8410.8175.900000115.1S41 K42S41-G44 PolarHBondContact O-N 2.68Å; K42-G44 VanDerWaalsContact C-N 3.28Å
45K78.4Confident88.7Confident66 Ų6640.9 Ų40.929%0.28723%0.227SC..  trans-88.1145172.7-65.2176.7179.4173.60110.8A40 S41 D43 W625A40-K45 CarbonylContact C-O 3.56Å; A40-K45 WeakPolarHBondContact CA-O 3.18Å; S41-K45 PolarHBondContact N-O 2.94Å; S41-K45 WeakPolarHBondContact OG-CB 3.33Å; S41-K45 PolarHBondContact OG-N 3.15Å; S41-K45 PolarHBondContact OG-O 3.39Å; D43-K45 PolarHBondContact OD1-N 2.73Å; K45-W625 HydrophobicContact CB-CZ2 4.43Å; K45-W625 HydrophobicContact CD-CH2 4.28Å; K45-W625 HydrophobicContact CD-CZ2 4.49Å
46E85.6Confident88.9Confident91 Ų9141.9 Ų41.943%0.42523%0.231SC..EExtended strand (participates in β ladder)trans-119.1136.6175.7-61.9-179.8173.700110.3F39 A40 W48F39-E46 CarbonylContact O-C 3.55Å; F39-E46 WeakPolarHBondContact O-CA 3.29Å; A40-E46 HydrophobicContact CB-CG 4.25Å; E46-W48 PolarHBondContact OE2-NE1 3.41Å
47L86.5Confident89Confident39 Ų3939.8 Ų39.820%0.20422%0.222CC..EExtended strand (participates in β ladder)trans-111122.5168.8172.865.7000108.3W16 I38 F39 I49 L79W16-L47 HydrophobicContact CH2-CD2 4.46Å; W16-L47 HydrophobicContact CZ3-CD2 4.42Å; I38-L47 CarbonylContact C-O 3.54Å; I38-L47 VanDerWaalsContact CA-O 3.31Å; I38-L47 WeakPolarHBondContact CA-O 3.48Å; F39-L47 HydrophobicContact CB-CB 4.32Å; F39-L47 PolarHBondContact N-O 3.37Å; F39-L47 PolarHBondContact O-N 2.99Å; L47-I49 HydrophobicContact CD1-CG1 4.41Å; L47-I49 HydrophobicContact CD2-CD1 4.12Å; L47-I49 HydrophobicContact CG-CD1 4.3Å; L47-I49 HydrophobicContact CG-CG1 4.25Å; L47-L79 HydrophobicContact CD2-CD1 3.94Å; L47-L79 HydrophobicContact CD2-CD2 3.93Å
48W88.6Confident88.8Confident87 Ų8743.8 Ų43.833%0.3324%0.241SC..EExtended strand (participates in β ladder)trans-111.6125.5179.9-69.559.4000109.4M1 L5 H36 I38 E46M1-W48 HydrophobicContact SD-CH2 4.25Å; L5-W48 HydrophobicContact CD1-CH2 4.02Å; L5-W48 HydrophobicContact CD1-CZ3 4.06Å; H36-W48 HydrophobicContact CB-CE3 4.17Å; H36-W48 AromaticContact CG-CE3 3.95Å; I38-W48 HydrophobicContact CD1-CD2 3.99Å; I38-W48 HydrophobicContact CD1-CE3 3.85Å; I38-W48 HydrophobicContact CD1-CH2 3.6Å; I38-W48 HydrophobicContact CD1-CZ2 3.74Å; I38-W48 HydrophobicContact CD1-CZ3 3.66Å; I38-W48 HydrophobicContact CG1-CD2 3.84Å; I38-W48 HydrophobicContact CG1-CE3 3.95Å; I38-W48 HydrophobicContact CG1-CG 4.29Å; I38-W48 HydrophobicContact CG1-CZ2 4.42Å; I38-W48 HydrophobicContact CG1-CZ3 4.29Å; I38-W48 HydrophobicContact CG2-CD2 4.43Å; I38-W48 HydrophobicContact CG2-CG 4.48Å; E46-W48 PolarHBondContact OE2-NE1 3.41Å
49I89.9Confident88.8Confident11 Ų1148.5 Ų48.56%0.05627%0.266CS..EExtended strand (participates in β ladder)trans-126.9113.4177.2-63.6173.5000108.2H36 L37 L47 I54 F77 L79H36-I49 CarbonylContact C-O 3.57Å; H36-I49 VanDerWaalsContact CA-O 3.3Å; H36-I49 WeakPolarHBondContact CA-O 3.4Å; L37-I49 HydrophobicContact CB-CB 4.41Å; L37-I49 HydrophobicContact CD2-CB 4.42Å; L37-I49 HydrophobicContact CD2-CD1 4.3Å; L37-I49 PolarHBondContact N-O 2.85Å; L37-I49 PolarHBondContact O-N 2.71Å; L47-I49 HydrophobicContact CD1-CG1 4.41Å; L47-I49 HydrophobicContact CD2-CD1 4.12Å; L47-I49 HydrophobicContact CG-CD1 4.3Å; L47-I49 HydrophobicContact CG-CG1 4.25Å; I49-I54 HydrophobicContact CG2-CD1 4.3Å; I49-I54 HydrophobicContact CG2-CG1 3.89Å; I49-F77 HydrophobicContact CD1-CD2 4.23Å; I49-F77 HydrophobicContact CD1-CE2 3.72Å; I49-F77 HydrophobicContact CD1-CZ 4.23Å; I49-F77 HydrophobicContact CG1-CE2 4.42Å; I49-F77 HydrophobicContact CG1-CZ 4.48Å; I49-F77 HydrophobicContact CG2-CE1 4.32Å; I49-F77 HydrophobicContact CG2-CE2 4.06Å; I49-F77 HydrophobicContact CG2-CZ 3.52Å; I49-L79 HydrophobicContact CD1-CB 4.36Å; I49-L79 HydrophobicContact CD1-CD2 3.47Å; I49-L79 VanDerWaalsContact CD1-CD2 3.47Å
50A89.8Confident88.7Confident21 Ų2150.4 Ų50.417%0.17428%0.278CS..EExtended strand (participates in β ladder)trans-67.5138.2172.900000110.3H36 C52 Q53H36-A50 PolarHBondContact CD2-N 3.43Å; A50-C52 VanDerWaalsContact C-N 3.27Å; A50-C52 PolarHBondContact O-N 2.92Å; A50-Q53 HydrophobicContact CB-CG 4.31Å; A50-Q53 VanDerWaalsContact O-CB 3.32Å; A50-Q53 WeakPolarHBondContact O-CB 3.46Å; A50-Q53 PolarHBondContact O-N 3.49Å
51Y91.5Very high88.6Confident10 Ų1054.9 Ų54.94%0.03931%0.306CS..G310 helixtrans-62.4-32.6-174.8-60-53.7000114L32 T33 T35 H36 L37 Q53 I54 L96 L99 S100L32-Y51 WeakPolarHBondContact CA-OH 3.3Å; T33-Y51 PolarHBondContact N-OH 3.32Å; T33-Y51 WeakPolarHBondContact O-CE2 3.15Å; T33-Y51 VanDerWaalsContact O-CZ 3.29Å; T33-Y51 PolarHBondContact O-OH 3.47Å; T35-Y51 VanDerWaalsContact C-CD2 3.44Å; T35-Y51 VanDerWaalsContact C-CE2 3.45Å; T35-Y51 VanDerWaalsContact O-CD2 3.32Å; T35-Y51 WeakPolarHBondContact O-CD2 3.4Å; T35-Y51 PolarHBondContact O-N 3.46Å; H36-Y51 VanDerWaalsContact C-CZ 3.44Å; H36-Y51 PolarHBondContact O-OH 2.86Å; L37-Y51 HydrophobicContact CB-CE1 4.08Å; Y51-Q53 PolarHBondContact O-N 3.43Å; Y51-I54 HydrophobicContact CD1-CD1 4.03Å; Y51-I54 WeakPolarHBondContact O-CB 3.44Å; Y51-I54 PolarHBondContact O-N 3.04Å; Y51-L96 HydrophobicContact CD1-CD2 4.05Å; Y51-L96 HydrophobicContact CE1-CD2 3.68Å; Y51-L99 VanDerWaalsContact CB-O 3.31Å; Y51-L99 WeakPolarHBondContact CB-O 3.4Å; Y51-L99 HydrophobicContact CD1-CB 4.12Å; Y51-L99 HydrophobicContact CD2-CB 3.59Å; Y51-L99 HydrophobicContact CD2-CD1 4.22Å; Y51-L99 HydrophobicContact CD2-CG 4.4Å; Y51-L99 HydrophobicContact CE1-CB 4.28Å; Y51-L99 HydrophobicContact CE1-CD1 4.2Å; Y51-L99 HydrophobicContact CE2-CB 3.74Å; Y51-L99 HydrophobicContact CE2-CD1 3.46Å; Y51-L99 VanDerWaalsContact CE2-CD1 3.46Å; Y51-L99 HydrophobicContact CE2-CG 4.1Å; Y51-L99 HydrophobicContact CG-CB 3.78Å; Y51-L99 VanDerWaalsContact CZ-CD1 3.43Å; Y51-L99 WeakPolarHBondContact OH-CD1 3.43Å; Y51-S100 WeakPolarHBondContact O-CB 3.4Å
52C89.9Confident88.7Confident9 Ų958.2 Ų58.26%0.06133%0.329CS..G310 helixtrans-59.6-24.217555.50000113.9A50 K74 P109 S433 C434A50-C52 VanDerWaalsContact C-N 3.27Å; A50-C52 PolarHBondContact O-N 2.92Å; C52-K74 WeakPolarHBondContact O-CD 3.29Å; C52-K74 VanDerWaalsContact O-CE 3.25Å; C52-K74 WeakPolarHBondContact O-CE 3.5Å; C52-K74 PolarHBondContact O-NZ 3.28Å; C52-P109 HydrophobicContact CB-CG 4.33Å; C52-S433 PolarHBondContact SG-O 3.25Å; C52-C434 HydrophobicContact CB-CB 4.17Å
53Q90.1Very high88.6Confident19 Ų1952.7 Ų52.79%0.08931%0.308CS..G310 helixtrans-82.3-14.3177.8-68.9-77.4-6.400112.4A50 Y51 A55 G73 K74 T75 F77 E429A50-Q53 HydrophobicContact CB-CG 4.31Å; A50-Q53 VanDerWaalsContact O-CB 3.32Å; A50-Q53 WeakPolarHBondContact O-CB 3.46Å; A50-Q53 PolarHBondContact O-N 3.49Å; Y51-Q53 PolarHBondContact O-N 3.43Å; Q53-A55 PolarHBondContact O-N 3.34Å; Q53-G73 CarbonylContact O-C 3.54Å; Q53-G73 VanDerWaalsContact O-CA 3.26Å; Q53-G73 WeakPolarHBondContact O-CA 3.48Å; Q53-K74 PolarHBondContact O-N 3.24Å; Q53-T75 PolarHBondContact OE1-OG1 3.28Å; Q53-F77 HydrophobicContact CB-CE1 4.03Å; Q53-F77 HydrophobicContact CB-CZ 4.48Å; Q53-E429 PolarHBondContact NE2-O 3.47Å; Q53-E429 VanDerWaalsContact NE2-O 3.17Å
54I92.5Very high88.8Confident3 Ų355.4 Ų55.42%0.01532%0.322CS..EExtended strand (participates in β ladder)trans-76.7122.9177.4-59.1177.9000108.2I49 Y51 V57 I71 K74 L96I49-I54 HydrophobicContact CG2-CD1 4.3Å; I49-I54 HydrophobicContact CG2-CG1 3.89Å; Y51-I54 HydrophobicContact CD1-CD1 4.03Å; Y51-I54 WeakPolarHBondContact O-CB 3.44Å; Y51-I54 PolarHBondContact O-N 3.04Å; I54-V57 HydrophobicContact CG2-CG2 3.76Å; I54-I71 HydrophobicContact CB-CG2 4.46Å; I54-I71 HydrophobicContact CD1-CG2 4.02Å; I54-I71 HydrophobicContact CG1-CG2 3.89Å; I54-I71 HydrophobicContact CG2-CG2 3.9Å; I54-K74 WeakPolarHBondContact O-CE 3.48Å; I54-L96 HydrophobicContact CD1-CD2 3.99Å
55A89.4Confident89.3Confident56 Ų5655.6 Ų55.646%0.46332%0.324SS..EExtended strand (participates in β ladder)trans-89-40.8174.200000111.2Q53 V72 K74Q53-A55 PolarHBondContact O-N 3.34Å; A55-V72 WeakPolarHBondContact CA-O 3.44Å; A55-V72 WeakPolarHBondContact CB-O 3.36Å; A55-V72 PolarHBondContact N-O 3.08Å; A55-K74 HydrophobicContact CB-CG 3.7Å
56N88.7Confident90Very high66 Ų6652.7 Ų52.735%0.35331%0.313SS..EExtended strand (participates in β ladder)trans-155.5150.2-176.9-164.47.1000111.1Q58 V72N56-Q58 PolarHBondContact ND2-NE2 2.84Å; N56-V72 HydrophobicContact CB-CB 4.47Å; N56-V72 PolarHBondContact N-O 2.95Å; N56-V72 PolarHBondContact O-N 2.93Å
57V93Very high90.5Very high11 Ų1149.4 Ų49.47%0.06730%0.299CS..EExtended strand (participates in β ladder)trans-123.3124.7170.4-175.70000107.1I54 I69 L70 L96 L97I54-V57 HydrophobicContact CG2-CG2 3.76Å; V57-I69 HydrophobicContact CG1-CG2 3.76Å; V57-L70 CarbonylContact C-O 3.5Å; V57-L70 WeakPolarHBondContact CA-O 3.41Å; V57-L96 HydrophobicContact CG1-CD1 4.37Å; V57-L96 HydrophobicContact CG2-CB 3.99Å; V57-L96 HydrophobicContact CG2-CD1 4.4Å; V57-L97 HydrophobicContact CB-CD2 4.12Å; V57-L97 HydrophobicContact CB-CG 4.49Å; V57-L97 HydrophobicContact CG2-CD2 4.48Å
58Q91.5Very high90.9Very high84 Ų8447.8 Ų47.839%0.39329%0.291SS..EExtended strand (participates in β ladder)trans-121.6154.7-178.4-56.6176.23.800109.7N56 P60 L70N56-Q58 PolarHBondContact ND2-NE2 2.84Å; Q58-P60 VanDerWaalsContact C-CD 3.43Å; Q58-P60 VanDerWaalsContact O-CD 3.25Å; Q58-P60 WeakPolarHBondContact O-CD 3.27Å; Q58-L70 HydrophobicContact CB-CB 4.23Å; Q58-L70 PolarHBondContact N-O 2.99Å; Q58-L70 PolarHBondContact O-N 3.36Å
59L92.5Very high91.2Very high99 Ų9943.7 Ų43.752%0.51828%0.276SS..  trans-113.382.2171.3-63.8175.7000109.5C68 I69 C93L59-C68 WeakPolarHBondContact CA-O 3.47Å; L59-I69 HydrophobicContact CD2-CG1 3.9Å; L59-C93 HydrophobicContact CD1-CB 4.45Å; L59-C93 HydrophobicContact CD2-CB 4.27Å
60P90.8Very high91.3Very high41 Ų4144.3 Ų44.327%0.26628%0.279SS..PPolyproline II helixtrans-61.5170.4171.9-21.433.1000112.6Q58 C68 L70Q58-P60 VanDerWaalsContact C-CD 3.43Å; Q58-P60 VanDerWaalsContact O-CD 3.25Å; Q58-P60 WeakPolarHBondContact O-CD 3.27Å; P60-C68 HydrophobicContact CB-CB 4.39Å; P60-C68 VanDerWaalsContact CD-O 3.31Å; P60-C68 WeakPolarHBondContact CD-O 3.26Å; P60-L70 HydrophobicContact CG-CB 3.69Å; P60-L70 HydrophobicContact CG-CD2 4.14Å
61P91.7Very high91.4Very high116 Ų11643.3 Ų43.375%0.75327%0.271SS*.PPolyproline II helixtrans-53.1143.6172.5-25.334.8000112.6
62S91.1Very high91.4Very high78 Ų7844.3 Ų44.355%0.54528%0.278SS..PPolyproline II helixtrans-56.3144.6178.1-59.30000112.2S66S62-S66 CarbonylContact C-O 3.55Å; S62-S66 WeakPolarHBondContact CA-O 3.44Å; S62-S66 WeakPolarHBondContact CB-O 3.42Å
63V87.1Confident91.4Very high39 Ų3944.1 Ų44.124%0.23628%0.277CS..BIsolated β-bridgetrans-117.5125.6178.2179.90000107.7G65 S66 L82V63-G65 PolarHBondContact O-N 2.96Å; V63-G65 VanDerWaalsContact O-N 3.14Å; V63-S66 PolarHBondContact N-O 2.8Å; V63-S66 PolarHBondContact O-N 2.94Å; V63-L82 HydrophobicContact CB-CD1 4.44Å; V63-L82 HydrophobicContact CB-CD2 3.95Å; V63-L82 HydrophobicContact CG1-CD1 4.44Å; V63-L82 HydrophobicContact CG2-CD2 4.31Å
64N87Confident91.4Very high150 Ų15044.5 Ų44.580%0.80228%0.279SS*.THydrogen-bonded Turntrans52.733.9179.7-57.6-25000114.2S66N64-S66 VanDerWaalsContact C-N 3.27Å; N64-S66 PolarHBondContact O-N 2.73Å
65G89.6Confident91.2Very high71 Ų7144.4 Ų44.473%0.73228%0.278SS*.THydrogen-bonded Turntrans82.3-7.7-178.400000115.3V63V63-G65 PolarHBondContact O-N 2.96Å; V63-G65 VanDerWaalsContact O-N 3.14Å
66S93.6Very high91.1Very high6 Ų642.2 Ų42.24%0.04226%0.258CS..BIsolated β-bridgetrans-91.6144.2174.9-59.70000111.5S62 V63 N64 V83 H84S62-S66 CarbonylContact C-O 3.55Å; S62-S66 WeakPolarHBondContact CA-O 3.44Å; S62-S66 WeakPolarHBondContact CB-O 3.42Å; V63-S66 PolarHBondContact N-O 2.8Å; V63-S66 PolarHBondContact O-N 2.94Å; N64-S66 VanDerWaalsContact C-N 3.27Å; N64-S66 PolarHBondContact O-N 2.73Å; S66-V83 CarbonylContact C-O 3.44Å; S66-H84 PolarHBondContact OG-CE1 2.67Å; S66-H84 VanDerWaalsContact OG-CE1 3.23Å; S66-H84 PolarHBondContact OG-ND1 3.16Å
67C95.5Very high90.9Very high22 Ų2239.7 Ų39.715%0.14924%0.244CC..EExtended strand (participates in β ladder)trans-65138.7170.9-62.80000110.4L82 V83 C89C67-L82 WeakPolarHBondContact O-CA 3.48Å; C67-V83 PolarHBondContact N-O 2.8Å; C67-V83 PolarHBondContact O-N 2.93Å; C67-C89 HydrophobicContact CB-CB 3.6Å; C67-C89 WeakPolarHBondContact CB-SG 3.16Å
68C94.5Very high90.5Very high5 Ų542.1 Ų42.13%0.03426%0.261CS..EExtended strand (participates in β ladder)trans-106.1123.1-177.6-174.90000109.9L59 P60 T80 L82L59-C68 WeakPolarHBondContact CA-O 3.47Å; P60-C68 HydrophobicContact CB-CB 4.39Å; P60-C68 VanDerWaalsContact CD-O 3.31Å; P60-C68 WeakPolarHBondContact CD-O 3.26Å; C68-T80 WeakPolarHBondContact SG-CG2 3.3Å; C68-L82 HydrophobicContact CB-CD2 4.08Å
69I95.2Very high90.4Very high0 Ų038.3 Ų38.30%024%0.243CC..EExtended strand (participates in β ladder)trans-109.6122.2171.6-53179.5000107.9V57 L59 I71 T80 L81 V83 C89 V92V57-I69 HydrophobicContact CG1-CG2 3.76Å; L59-I69 HydrophobicContact CD2-CG1 3.9Å; I69-I71 HydrophobicContact CG2-CG1 4.11Å; I69-T80 CarbonylContact O-C 3.46Å; I69-T80 WeakPolarHBondContact O-CA 3.46Å; I69-L81 HydrophobicContact CB-CB 4.35Å; I69-L81 PolarHBondContact N-O 3.15Å; I69-L81 PolarHBondContact O-N 3.22Å; I69-V83 HydrophobicContact CD1-CG2 3.82Å; I69-V83 HydrophobicContact CG1-CG2 4.41Å; I69-C89 VanDerWaalsContact CG1-SG 3.55Å; I69-V92 HydrophobicContact CD1-CB 3.88Å; I69-V92 HydrophobicContact CD1-CG1 3.51Å
70L92.2Very high90.3Very high25 Ų2533.9 Ų33.913%0.13122%0.22CC..EExtended strand (participates in β ladder)trans-109.5114.4177179.567.9000109.6V57 Q58 P60 V72 C78 T80V57-L70 CarbonylContact C-O 3.5Å; V57-L70 WeakPolarHBondContact CA-O 3.41Å; Q58-L70 HydrophobicContact CB-CB 4.23Å; Q58-L70 PolarHBondContact N-O 2.99Å; Q58-L70 PolarHBondContact O-N 3.36Å; P60-L70 HydrophobicContact CG-CB 3.69Å; P60-L70 HydrophobicContact CG-CD2 4.14Å; L70-V72 HydrophobicContact CD2-CG2 4.42Å; L70-V72 HydrophobicContact CG-CG2 4.2Å; L70-C78 WeakPolarHBondContact CD1-SG 3.28Å; L70-T80 WeakPolarHBondContact CD1-OG1 3.5Å
71I92.8Very high90.5Very high0 Ų031.9 Ų31.90%021%0.208CC..EExtended strand (participates in β ladder)trans-104116.9178.2-55.5174.9000108L37 I54 I69 F77 C78 L79 L81 L96L37-I71 HydrophobicContact CD1-CD1 3.44Å; L37-I71 VanDerWaalsContact CD1-CD1 3.44Å; I54-I71 HydrophobicContact CB-CG2 4.46Å; I54-I71 HydrophobicContact CD1-CG2 4.02Å; I54-I71 HydrophobicContact CG1-CG2 3.89Å; I54-I71 HydrophobicContact CG2-CG2 3.9Å; I69-I71 HydrophobicContact CG2-CG1 4.11Å; I71-F77 HydrophobicContact CG2-CE2 4.06Å; I71-C78 WeakPolarHBondContact O-CA 3.44Å; I71-L79 HydrophobicContact CB-CB 4.26Å; I71-L79 HydrophobicContact CD1-CD2 4.22Å; I71-L79 PolarHBondContact N-O 3.25Å; I71-L79 PolarHBondContact O-N 3.46Å; I71-L81 HydrophobicContact CD1-CD1 4.03Å; I71-L96 HydrophobicContact CD1-CD1 3.69Å; I71-L96 HydrophobicContact CG1-CD1 4.26Å
72V89.9Confident90.7Very high30 Ų3026.9 Ų26.918%0.18217%0.174CC..EExtended strand (participates in β ladder)trans-104.7127.2178-177.20000108.9A55 N56 L70A55-V72 WeakPolarHBondContact CA-O 3.44Å; A55-V72 WeakPolarHBondContact CB-O 3.36Å; A55-V72 PolarHBondContact N-O 3.08Å; N56-V72 HydrophobicContact CB-CB 4.47Å; N56-V72 PolarHBondContact N-O 2.95Å; N56-V72 PolarHBondContact O-N 2.93Å; L70-V72 HydrophobicContact CD2-CG2 4.42Å; L70-V72 HydrophobicContact CG-CG2 4.2Å
73G91Very high90.9Very high5 Ų523.2 Ų23.25%0.05215%0.149CC..EExtended strand (participates in β ladder)trans-90.7151-179.800000114.3Q53 T75 F76 F77Q53-G73 CarbonylContact O-C 3.54Å; Q53-G73 VanDerWaalsContact O-CA 3.26Å; Q53-G73 WeakPolarHBondContact O-CA 3.48Å; G73-T75 PolarHBondContact O-N 3.17Å; G73-F76 PolarHBondContact O-N 3.31Å; G73-F77 PolarHBondContact N-O 3.16Å
74K90.9Very high91.2Very high28 Ų2827.3 Ų27.312%0.12217%0.165CC..THydrogen-bonded Turntrans-65.5-24.2170.8-62.5-179.1-173.9170.30112.4C52 Q53 I54 A55 A385 Y432C52-K74 WeakPolarHBondContact O-CD 3.29Å; C52-K74 VanDerWaalsContact O-CE 3.25Å; C52-K74 WeakPolarHBondContact O-CE 3.5Å; C52-K74 PolarHBondContact O-NZ 3.28Å; Q53-K74 PolarHBondContact O-N 3.24Å; I54-K74 WeakPolarHBondContact O-CE 3.48Å; A55-K74 HydrophobicContact CB-CG 3.7Å; K74-A385 PolarHBondContact NZ-O 3.24Å; K74-Y432 HydrophobicContact CB-CD1 3.61Å; K74-Y432 HydrophobicContact CB-CD2 4.28Å; K74-Y432 HydrophobicContact CB-CE1 4.19Å; K74-Y432 HydrophobicContact CB-CG 3.65Å; K74-Y432 HydrophobicContact CD-CD1 3.72Å; K74-Y432 HydrophobicContact CD-CG 4.31Å; K74-Y432 HydrophobicContact CG-CD1 4.19Å
75T88.1Confident91.5Very high1 Ų123.6 Ų23.61%0.00615%0.145CC..THydrogen-bonded Turntrans-101.329.3179.145.70000113Q53 G73 F77 Y432 Y507Q53-T75 PolarHBondContact OE1-OG1 3.28Å; G73-T75 PolarHBondContact O-N 3.17Å; T75-F77 VanDerWaalsContact C-N 3.29Å; T75-F77 PolarHBondContact O-N 2.99Å; T75-Y432 HydrophobicContact CG2-CD2 3.84Å; T75-Y432 HydrophobicContact CG2-CG 4.38Å; T75-Y507 VanDerWaalsContact O-CE2 3.23Å; T75-Y507 WeakPolarHBondContact O-CE2 3.31Å
76F87.4Confident91.6Very high9 Ų927.5 Ų27.54%0.03914%0.144CC..SBendtrans7216.4169.9-51.8-40.2000115.3G73 L282 L286 W290 T400 L503 Y504G73-F76 PolarHBondContact O-N 3.31Å; F76-L282 HydrophobicContact CE1-CD1 4.34Å; F76-L282 HydrophobicContact CE1-CD2 3.85Å; F76-L282 HydrophobicContact CE1-CG 4.43Å; F76-L282 HydrophobicContact CZ-CD1 4.34Å; F76-L282 HydrophobicContact CZ-CD2 4Å; F76-L286 HydrophobicContact CD1-CD1 3.61Å; F76-L286 HydrophobicContact CD1-CD2 3.79Å; F76-L286 HydrophobicContact CD1-CG 4.35Å; F76-L286 HydrophobicContact CE1-CD1 3.72Å; F76-L286 HydrophobicContact CE1-CD2 4.22Å; F76-L286 HydrophobicContact CG-CD2 4.27Å; F76-W290 VanDerWaalsContact CA-CZ2 3.48Å; F76-W290 HydrophobicContact CB-CH2 4.23Å; F76-W290 HydrophobicContact CB-CZ2 3.59Å; F76-W290 HydrophobicContact CD1-CH2 4.26Å; F76-W290 HydrophobicContact CD1-CZ2 4.2Å; F76-W290 HydrophobicContact CG-CZ2 4.29Å; F76-W290 WeakPolarHBondContact O-CZ2 3.44Å; F76-T400 HydrophobicContact CE2-CG2 4.17Å; F76-T400 HydrophobicContact CZ-CG2 4.03Å; F76-L503 HydrophobicContact CD2-CD1 4.1Å; F76-L503 HydrophobicContact CD2-CG 3.97Å; F76-L503 HydrophobicContact CE2-CD1 4.1Å; F76-L503 HydrophobicContact CE2-CD2 4.03Å; F76-L503 HydrophobicContact CE2-CG 3.85Å; F76-Y504 AromaticContact CD2-CD1 3.71Å; F76-Y504 HydrophobicContact CD2-CD1 3.71Å; F76-Y504 HydrophobicContact CD2-CE1 4.08Å; F76-Y504 HydrophobicContact CE1-CD1 4.48Å; F76-Y504 HydrophobicContact CE1-CE1 4.41Å; F76-Y504 AromaticContact CE2-CD1 3.6Å; F76-Y504 HydrophobicContact CE2-CD1 3.6Å; F76-Y504 AromaticContact CE2-CE1 3.47Å; F76-Y504 HydrophobicContact CE2-CE1 3.47Å; F76-Y504 VanDerWaalsContact CE2-CE1 3.47Å; F76-Y504 HydrophobicContact CG-CD1 4.19Å; F76-Y504 HydrophobicContact CZ-CD1 4.02Å; F76-Y504 AromaticContact CZ-CE1 3.67Å; F76-Y504 HydrophobicContact CZ-CE1 3.67Å
77F84.7Confident91.6Very high13 Ų1331.3 Ų31.36%0.05717%0.171CC..  trans-87.3152.1166.773.5-96000111.5I49 Q53 I71 G73 T75 Y507I49-F77 HydrophobicContact CD1-CD2 4.23Å; I49-F77 HydrophobicContact CD1-CE2 3.72Å; I49-F77 HydrophobicContact CD1-CZ 4.23Å; I49-F77 HydrophobicContact CG1-CE2 4.42Å; I49-F77 HydrophobicContact CG1-CZ 4.48Å; I49-F77 HydrophobicContact CG2-CE1 4.32Å; I49-F77 HydrophobicContact CG2-CE2 4.06Å; I49-F77 HydrophobicContact CG2-CZ 3.52Å; Q53-F77 HydrophobicContact CB-CE1 4.03Å; Q53-F77 HydrophobicContact CB-CZ 4.48Å; I71-F77 HydrophobicContact CG2-CE2 4.06Å; G73-F77 PolarHBondContact N-O 3.16Å; T75-F77 VanDerWaalsContact C-N 3.29Å; T75-F77 PolarHBondContact O-N 2.99Å; F77-Y507 VanDerWaalsContact CA-CD2 3.46Å; F77-Y507 HydrophobicContact CB-CD1 3.63Å; F77-Y507 HydrophobicContact CB-CD2 3.36Å; F77-Y507 HydrophobicContact CB-CE1 3.82Å; F77-Y507 HydrophobicContact CB-CE2 3.59Å; F77-Y507 HydrophobicContact CB-CG 3.37Å; F77-Y507 HydrophobicContact CD1-CE2 4.41Å
78C84.5Confident91.5Very high62 Ų6233.2 Ų33.242%0.41918%0.18SC..EExtended strand (participates in β ladder)trans-135.4118.1174.7-1770000107.9L70 I71L70-C78 WeakPolarHBondContact CD1-SG 3.28Å; I71-C78 WeakPolarHBondContact O-CA 3.44Å
79L88.3Confident91.5Very high4 Ų433.2 Ų33.22%0.02118%0.18CC..EExtended strand (participates in β ladder)trans-116.4117.1179.9173.964.2000108.9W16 L37 L47 I49 I71 L81W16-L79 HydrophobicContact CD2-CD1 4.04Å; W16-L79 HydrophobicContact CG-CD1 3.72Å; L37-L79 HydrophobicContact CD2-CD2 4.17Å; L47-L79 HydrophobicContact CD2-CD1 3.94Å; L47-L79 HydrophobicContact CD2-CD2 3.93Å; I49-L79 HydrophobicContact CD1-CB 4.36Å; I49-L79 HydrophobicContact CD1-CD2 3.47Å; I49-L79 VanDerWaalsContact CD1-CD2 3.47Å; I71-L79 HydrophobicContact CB-CB 4.26Å; I71-L79 HydrophobicContact CD1-CD2 4.22Å; I71-L79 PolarHBondContact N-O 3.25Å; I71-L79 PolarHBondContact O-N 3.46Å; L79-L81 HydrophobicContact CD1-CD2 3.86Å; L79-L81 HydrophobicContact CD1-CG 4.48Å; L79-L81 HydrophobicContact CD2-CD1 4.28Å; L79-L81 HydrophobicContact CD2-CD2 4.06Å; L79-L81 HydrophobicContact CD2-CG 4.2Å; L79-L81 HydrophobicContact CG-CD2 3.93Å; L79-L81 HydrophobicContact CG-CG 4.03Å
80T91.2Very high91.4Very high6 Ų635.4 Ų35.44%0.03720%0.198CC..EExtended strand (participates in β ladder)trans-100.6123.6171.9-53.70000109.2Y17 Q19 C68 I69 L70Y17-T80 HydrophobicContact CD1-CG2 4.06Å; Y17-T80 PolarHBondContact N-O 2.96Å; Y17-T80 WeakPolarHBondContact O-CB 3.49Å; Q19-T80 PolarHBondContact NE2-OG1 3.34Å; C68-T80 WeakPolarHBondContact SG-CG2 3.3Å; I69-T80 CarbonylContact O-C 3.46Å; I69-T80 WeakPolarHBondContact O-CA 3.46Å; L70-T80 WeakPolarHBondContact CD1-OG1 3.5Å
81L94.5Very high91.4Very high0 Ų037.6 Ų37.60%021%0.21CC..EExtended strand (participates in β ladder)trans-114.4131.7175.6-58.6177.3000109.3V14 V15 W16 L30 L37 F39 I69 I71 L79V14-L81 HydrophobicContact CG1-CB 3.95Å; V14-L81 HydrophobicContact CG1-CD2 4.05Å; V14-L81 HydrophobicContact CG1-CG 4.4Å; V15-L81 CarbonylContact O-C 3.6Å; V15-L81 WeakPolarHBondContact O-CA 3.4Å; W16-L81 HydrophobicContact CB-CD2 4.31Å; L30-L81 HydrophobicContact CD1-CD1 3.83Å; L30-L81 HydrophobicContact CD2-CD1 3.97Å; L37-L81 HydrophobicContact CD1-CD1 4.36Å; F39-L81 HydrophobicContact CD2-CD2 4.46Å; I69-L81 HydrophobicContact CB-CB 4.35Å; I69-L81 PolarHBondContact N-O 3.15Å; I69-L81 PolarHBondContact O-N 3.22Å; I71-L81 HydrophobicContact CD1-CD1 4.03Å; L79-L81 HydrophobicContact CD1-CD2 3.86Å; L79-L81 HydrophobicContact CD1-CG 4.48Å; L79-L81 HydrophobicContact CD2-CD1 4.28Å; L79-L81 HydrophobicContact CD2-CD2 4.06Å; L79-L81 HydrophobicContact CD2-CG 4.2Å; L79-L81 HydrophobicContact CG-CD2 3.93Å; L79-L81 HydrophobicContact CG-CG 4.03Å
82L95.7Very high91.5Very high10 Ų1037.6 Ų37.65%0.05221%0.21CC..EExtended strand (participates in β ladder)trans-101.4123.1169.6-52.1177.8000109V15 Y17 V63 C67 C68V15-L82 HydrophobicContact CB-CB 4.15Å; V15-L82 PolarHBondContact N-O 2.91Å; V15-L82 PolarHBondContact O-N 3.1Å; Y17-L82 HydrophobicContact CD2-CD1 3.74Å; Y17-L82 HydrophobicContact CE2-CD1 4.4Å; Y17-L82 HydrophobicContact CG-CD1 3.86Å; Y17-L82 HydrophobicContact CG-CG 4.18Å; V63-L82 HydrophobicContact CB-CD1 4.44Å; V63-L82 HydrophobicContact CB-CD2 3.95Å; V63-L82 HydrophobicContact CG1-CD1 4.44Å; V63-L82 HydrophobicContact CG2-CD2 4.31Å; C67-L82 WeakPolarHBondContact O-CA 3.48Å; C68-L82 HydrophobicContact CB-CD2 4.08Å
83V95.9Very high91.6Very high1 Ų136.6 Ų36.61%0.00620%0.204CC..EExtended strand (participates in β ladder)trans-115.5127.5178.8-176.90000108V11 V14 S66 C67 I69 D88 C89V11-V83 HydrophobicContact CG1-CG1 4Å; V14-V83 HydrophobicContact CG1-CG2 4.38Å; V14-V83 HydrophobicContact CG2-CG2 4.28Å; S66-V83 CarbonylContact C-O 3.44Å; C67-V83 PolarHBondContact N-O 2.8Å; C67-V83 PolarHBondContact O-N 2.93Å; I69-V83 HydrophobicContact CD1-CG2 3.82Å; I69-V83 HydrophobicContact CG1-CG2 4.41Å; V83-D88 HydrophobicContact CG1-CB 3.88Å; V83-C89 HydrophobicContact CB-CB 4.15Å; V83-C89 HydrophobicContact CG1-CB 4.19Å
84H93.3Very high91.7Very high125 Ų12541.5 Ų41.558%0.57923%0.229SC*.SBendtrans-73.2-44.3-176.2-76.4-73.6000112.8S66S66-H84 PolarHBondContact OG-CE1 2.67Å; S66-H84 VanDerWaalsContact OG-CE1 3.23Å; S66-H84 PolarHBondContact OG-ND1 3.16Å
85D92.7Very high91.8Very high73 Ų7341.2 Ų41.239%0.3923%0.23SC..  trans-85.4133-179.2-17875000111.8S87 D88 C89D85-S87 VanDerWaalsContact OD2-CA 3.28Å; D85-S87 WeakPolarHBondContact OD2-CA 3.12Å; D85-S87 WeakPolarHBondContact OD2-CB 3.42Å; D85-S87 PolarHBondContact OD2-N 3.01Å; D85-D88 HydrophobicContact CB-CB 4.03Å; D85-D88 PolarHBondContact OD2-N 3.08Å; D85-C89 WeakPolarHBondContact O-CB 3.15Å; D85-C89 PolarHBondContact O-N 3.19Å
86Q91.9Very high92.1Very high152 Ų15241.2 Ų41.271%0.7123%0.229SC*.Hα-helixtrans-71.2-32.4-177-175174.1-4.600112.4C89 A90Q86-C89 PolarHBondContact O-N 3.11Å; Q86-A90 PolarHBondContact O-N 3.23Å
87S92.8Very high92.2Very high87 Ų8742.7 Ų42.761%0.60824%0.238SC*.Hα-helixtrans-72.1-43.3178.5-45.40000110.4D85 C89 A90 N91D85-S87 VanDerWaalsContact OD2-CA 3.28Å; D85-S87 WeakPolarHBondContact OD2-CA 3.12Å; D85-S87 WeakPolarHBondContact OD2-CB 3.42Å; D85-S87 PolarHBondContact OD2-N 3.01Å; S87-C89 VanDerWaalsContact C-N 3.31Å; S87-C89 PolarHBondContact O-N 2.65Å; S87-A90 PolarHBondContact O-N 3.02Å; S87-N91 WeakPolarHBondContact O-CB 3.43Å; S87-N91 PolarHBondContact O-N 3.26Å
88D94.3Very high92.4Very high61 Ų6145.5 Ų45.533%0.32626%0.263SS..Hα-helixtrans-59.7-42.7172.4-75.1-19.2000111V11 V83 D85 A90 N91 V92V11-D88 HydrophobicContact CG1-CB 4.01Å; V11-D88 HydrophobicContact CG2-CB 4.07Å; V83-D88 HydrophobicContact CG1-CB 3.88Å; D85-D88 HydrophobicContact CB-CB 4.03Å; D85-D88 PolarHBondContact OD2-N 3.08Å; D88-A90 PolarHBondContact O-N 3.02Å; D88-N91 PolarHBondContact O-N 3.29Å; D88-V92 WeakPolarHBondContact O-CB 3.28Å; D88-V92 VanDerWaalsContact O-CG2 3.26Å; D88-V92 WeakPolarHBondContact O-CG2 3.34Å; D88-V92 PolarHBondContact O-N 2.83Å
89C94.4Very high92.6Very high6 Ų644.7 Ų44.74%0.04126%0.255CS..Hα-helixtrans-60.1-45.7176.6-176.60000112.3C67 I69 V83 D85 Q86 S87 C93C67-C89 HydrophobicContact CB-CB 3.6Å; C67-C89 WeakPolarHBondContact CB-SG 3.16Å; I69-C89 VanDerWaalsContact CG1-SG 3.55Å; V83-C89 HydrophobicContact CB-CB 4.15Å; V83-C89 HydrophobicContact CG1-CB 4.19Å; D85-C89 WeakPolarHBondContact O-CB 3.15Å; D85-C89 PolarHBondContact O-N 3.19Å; Q86-C89 PolarHBondContact O-N 3.11Å; S87-C89 VanDerWaalsContact C-N 3.31Å; S87-C89 PolarHBondContact O-N 2.65Å; C89-C93 WeakPolarHBondContact O-CB 3.28Å; C89-C93 PolarHBondContact O-N 3.31Å
90A92.1Very high92.8Very high45 Ų4545.2 Ų45.237%0.37226%0.259SS..Hα-helixtrans-62.8-47.2177.200000111.1Q86 S87 D88 V92 C93 D94Q86-A90 PolarHBondContact O-N 3.23Å; S87-A90 PolarHBondContact O-N 3.02Å; D88-A90 PolarHBondContact O-N 3.02Å; A90-V92 PolarHBondContact O-N 3.37Å; A90-C93 WeakPolarHBondContact O-CB 3.14Å; A90-C93 PolarHBondContact O-N 3.47Å; A90-D94 PolarHBondContact O-N 2.9Å
91N93.3Very high92.7Very high72 Ų7249.9 Ų49.939%0.38528%0.276SS..Hα-helixtrans-60.2-44.2179-174.724.4000112.6S87 D88 T95S87-N91 WeakPolarHBondContact O-CB 3.43Å; S87-N91 PolarHBondContact O-N 3.26Å; D88-N91 PolarHBondContact O-N 3.29Å; N91-T95 VanDerWaalsContact O-CB 3.23Å; N91-T95 WeakPolarHBondContact O-CB 3.5Å; N91-T95 PolarHBondContact O-N 3.24Å; N91-T95 PolarHBondContact O-OG1 2.92Å; N91-T95 PolarHBondContact OD1-OG1 3.06Å
92V94.5Very high92.5Very high0 Ų050.8 Ų50.80%028%0.281CS..Hα-helixtrans-61.1-45.7175.3168.40000110.6V11 L30 L32 I69 D88 A90 L96V11-V92 HydrophobicContact CG2-CG2 3.63Å; L30-V92 HydrophobicContact CD2-CG1 3.74Å; L30-V92 HydrophobicContact CD2-CG2 3.94Å; L32-V92 HydrophobicContact CD1-CB 4.41Å; L32-V92 HydrophobicContact CD1-CG1 4.23Å; L32-V92 HydrophobicContact CD1-CG2 4.37Å; I69-V92 HydrophobicContact CD1-CB 3.88Å; I69-V92 HydrophobicContact CD1-CG1 3.51Å; D88-V92 WeakPolarHBondContact O-CB 3.28Å; D88-V92 VanDerWaalsContact O-CG2 3.26Å; D88-V92 WeakPolarHBondContact O-CG2 3.34Å; D88-V92 PolarHBondContact O-N 2.83Å; A90-V92 PolarHBondContact O-N 3.37Å; V92-L96 HydrophobicContact CG1-CD1 3.8Å; V92-L96 HydrophobicContact CG1-CG 4.35Å; V92-L96 WeakPolarHBondContact O-CB 3.43Å; V92-L96 WeakPolarHBondContact O-CG 3.22Å; V92-L96 PolarHBondContact O-N 3.04Å
93C93.3Very high92.2Very high9 Ų954.4 Ų54.46%0.06131%0.308CS..Hα-helixtrans-62.3-50.5179.8-168.50000111.8L59 C89 A90 T95 L96 L97L59-C93 HydrophobicContact CD1-CB 4.45Å; L59-C93 HydrophobicContact CD2-CB 4.27Å; C89-C93 WeakPolarHBondContact O-CB 3.28Å; C89-C93 PolarHBondContact O-N 3.31Å; A90-C93 WeakPolarHBondContact O-CB 3.14Å; A90-C93 PolarHBondContact O-N 3.47Å; C93-T95 VanDerWaalsContact C-N 3.34Å; C93-T95 PolarHBondContact O-N 2.92Å; C93-L96 PolarHBondContact O-N 3.35Å; C93-L97 WeakPolarHBondContact O-CB 3.45Å; C93-L97 VanDerWaalsContact O-CG 3.31Å; C93-L97 WeakPolarHBondContact O-CG 3.41Å; C93-L97 PolarHBondContact O-N 3.18Å
94D92.1Very high91.9Very high108 Ų10856 Ų5658%0.57832%0.319SS*.Hα-helixtrans-61.9-42.8-179.4-70.7-19.9000111.4A90 L97 A98A90-D94 PolarHBondContact O-N 2.9Å; D94-L97 PolarHBondContact O-N 3.12Å; D94-A98 WeakPolarHBondContact O-CB 3.49Å; D94-A98 PolarHBondContact O-N 3.31Å
95T93Very high91.7Very high22 Ų2251.1 Ų51.114%0.13530%0.296CS..Hα-helixtrans-63.4-45176.5-59.80000111.4L32 N91 C93 A98 L99L32-T95 HydrophobicContact CB-CG2 4.17Å; L32-T95 HydrophobicContact CD1-CG2 3.54Å; N91-T95 VanDerWaalsContact O-CB 3.23Å; N91-T95 WeakPolarHBondContact O-CB 3.5Å; N91-T95 PolarHBondContact O-N 3.24Å; N91-T95 PolarHBondContact O-OG1 2.92Å; N91-T95 PolarHBondContact OD1-OG1 3.06Å; C93-T95 VanDerWaalsContact C-N 3.34Å; C93-T95 PolarHBondContact O-N 2.92Å; T95-A98 PolarHBondContact O-N 3.44Å; T95-L99 HydrophobicContact CG2-CD1 3.6Å; T95-L99 HydrophobicContact CG2-CG 4.33Å; T95-L99 WeakPolarHBondContact O-CB 3.48Å; T95-L99 VanDerWaalsContact O-CG 3.31Å; T95-L99 WeakPolarHBondContact O-CG 3.38Å; T95-L99 PolarHBondContact O-N 2.81Å
96L93.6Very high91.5Very high0 Ų051.1 Ų51.10%029%0.294CS..Hα-helixtrans-64.7-40.6177.7-73.7173.7000112.2L32 L37 Y51 I54 V57 I71 V92 C93 A98 L99 S100L32-L96 HydrophobicContact CD1-CD2 4.46Å; L32-L96 HydrophobicContact CD1-CG 4.22Å; L32-L96 HydrophobicContact CD2-CD2 3.77Å; L32-L96 HydrophobicContact CD2-CG 4.25Å; L37-L96 HydrophobicContact CB-CD2 4.31Å; L37-L96 HydrophobicContact CD1-CD1 4.1Å; L37-L96 HydrophobicContact CD1-CD2 3.83Å; Y51-L96 HydrophobicContact CD1-CD2 4.05Å; Y51-L96 HydrophobicContact CE1-CD2 3.68Å; I54-L96 HydrophobicContact CD1-CD2 3.99Å; V57-L96 HydrophobicContact CG1-CD1 4.37Å; V57-L96 HydrophobicContact CG2-CB 3.99Å; V57-L96 HydrophobicContact CG2-CD1 4.4Å; I71-L96 HydrophobicContact CD1-CD1 3.69Å; I71-L96 HydrophobicContact CG1-CD1 4.26Å; V92-L96 HydrophobicContact CG1-CD1 3.8Å; V92-L96 HydrophobicContact CG1-CG 4.35Å; V92-L96 WeakPolarHBondContact O-CB 3.43Å; V92-L96 WeakPolarHBondContact O-CG 3.22Å; V92-L96 PolarHBondContact O-N 3.04Å; C93-L96 PolarHBondContact O-N 3.35Å; L96-A98 VanDerWaalsContact C-N 3.33Å; L96-L99 PolarHBondContact O-N 2.97Å; L96-S100 WeakPolarHBondContact O-CB 3.49Å; L96-S100 PolarHBondContact O-N 3.43Å; L96-S100 PolarHBondContact O-OG 2.77Å
97L90.2Very high91.4Very high41 Ų4149.2 Ų49.222%0.21529%0.285CS..Hα-helixtrans-65.3-37.6176.5-72.3173.8000111.8V57 C93 D94 R101V57-L97 HydrophobicContact CB-CD2 4.12Å; V57-L97 HydrophobicContact CB-CG 4.49Å; V57-L97 HydrophobicContact CG2-CD2 4.48Å; C93-L97 WeakPolarHBondContact O-CB 3.45Å; C93-L97 VanDerWaalsContact O-CG 3.31Å; C93-L97 WeakPolarHBondContact O-CG 3.41Å; C93-L97 PolarHBondContact O-N 3.18Å; D94-L97 PolarHBondContact O-N 3.12Å; L97-R101 WeakPolarHBondContact O-CB 3.48Å; L97-R101 VanDerWaalsContact O-CD 3.24Å; L97-R101 WeakPolarHBondContact O-CD 3.5Å; L97-R101 WeakPolarHBondContact O-CG 3.32Å
98A88.7Confident91.4Very high72 Ų7245.1 Ų45.160%0.59526%0.257SS*.Hα-helixtrans-66.4-47.1174.800000111.9D94 T95 L96D94-A98 WeakPolarHBondContact O-CB 3.49Å; D94-A98 PolarHBondContact O-N 3.31Å; T95-A98 PolarHBondContact O-N 3.44Å; L96-A98 VanDerWaalsContact C-N 3.33Å
99L89.8Confident91.2Very high45 Ų4544.2 Ų44.224%0.23625%0.254CS..Hα-helixtrans-79.8-23.4-173.4-64.3172.8000114.1Y8 Y51 T95 L96 R101Y8-L99 HydrophobicContact CD2-CD1 4.3Å; Y51-L99 VanDerWaalsContact CB-O 3.31Å; Y51-L99 WeakPolarHBondContact CB-O 3.4Å; Y51-L99 HydrophobicContact CD1-CB 4.12Å; Y51-L99 HydrophobicContact CD2-CB 3.59Å; Y51-L99 HydrophobicContact CD2-CD1 4.22Å; Y51-L99 HydrophobicContact CD2-CG 4.4Å; Y51-L99 HydrophobicContact CE1-CB 4.28Å; Y51-L99 HydrophobicContact CE1-CD1 4.2Å; Y51-L99 HydrophobicContact CE2-CB 3.74Å; Y51-L99 HydrophobicContact CE2-CD1 3.46Å; Y51-L99 VanDerWaalsContact CE2-CD1 3.46Å; Y51-L99 HydrophobicContact CE2-CG 4.1Å; Y51-L99 HydrophobicContact CG-CB 3.78Å; Y51-L99 VanDerWaalsContact CZ-CD1 3.43Å; Y51-L99 WeakPolarHBondContact OH-CD1 3.43Å; T95-L99 HydrophobicContact CG2-CD1 3.6Å; T95-L99 HydrophobicContact CG2-CG 4.33Å; T95-L99 WeakPolarHBondContact O-CB 3.48Å; T95-L99 VanDerWaalsContact O-CG 3.31Å; T95-L99 WeakPolarHBondContact O-CG 3.38Å; T95-L99 PolarHBondContact O-N 2.81Å; L96-L99 PolarHBondContact O-N 2.97Å; L99-R101 VanDerWaalsContact C-N 3.31Å
100S91.2Very high91.2Very high15 Ų1544 Ų4411%0.10525%0.252CS..THydrogen-bonded Turntrans-84.90.217760.80000114.4Y51 L96 P102Y51-S100 WeakPolarHBondContact O-CB 3.4Å; L96-S100 WeakPolarHBondContact O-CB 3.49Å; L96-S100 PolarHBondContact O-N 3.43Å; L96-S100 PolarHBondContact O-OG 2.77Å; S100-P102 VanDerWaalsContact C-CD 3.47Å; S100-P102 WeakPolarHBondContact O-CD 3.3Å
101R89.6Confident91.2Very high104 Ų10444 Ų4439%0.39224%0.244SC..  trans-122.568.4-174.5-67-178.1178.4-179.3-1111.9L97 L99 Y388L97-R101 WeakPolarHBondContact O-CB 3.48Å; L97-R101 VanDerWaalsContact O-CD 3.24Å; L97-R101 WeakPolarHBondContact O-CD 3.5Å; L97-R101 WeakPolarHBondContact O-CG 3.32Å; L99-R101 VanDerWaalsContact C-N 3.31Å; R101-Y388 HydrophobicContact CB-CD1 4.38Å; R101-Y388 HydrophobicContact CB-CD2 3.94Å; R101-Y388 HydrophobicContact CB-CG 3.75Å; R101-Y388 VanDerWaalsContact CD-CE2 3.48Å; R101-Y388 HydrophobicContact CG-CD2 3.52Å; R101-Y388 HydrophobicContact CG-CE2 4Å; R101-Y388 HydrophobicContact CG-CG 3.9Å; R101-Y388 PolarHBondContact NH1-OH 2.92Å
102P89.8Confident91.1Very high18 Ų1844.4 Ų44.412%0.11725%0.253CS..  trans-60140.4177.728.4-36.4000110.7S100 E107 L108 H386 Y388S100-P102 VanDerWaalsContact C-CD 3.47Å; S100-P102 WeakPolarHBondContact O-CD 3.3Å; P102-E107 WeakPolarHBondContact CA-OE2 3.34Å; P102-E107 HydrophobicContact CB-CB 4.08Å; P102-L108 HydrophobicContact CB-CD2 4.13Å; P102-L108 HydrophobicContact CG-CD2 3.71Å; P102-H386 WeakPolarHBondContact CG-O 3.42Å; P102-Y388 WeakPolarHBondContact O-CB 3.45Å; P102-Y388 PolarHBondContact O-N 3.26Å
103S89.4Confident90.9Very high87 Ų8746.6 Ų46.661%0.60826%0.262SS*.SBendtrans-88-21.1-176.179.10000113.1E107 V387S103-E107 PolarHBondContact N-OE2 2.9Å; S103-E107 VanDerWaalsContact OG-CD 3.31Å; S103-E107 PolarHBondContact OG-OE1 2.93Å; S103-E107 PolarHBondContact OG-OE2 3.17Å; S103-V387 VanDerWaalsContact O-CG1 3.3Å; S103-V387 WeakPolarHBondContact O-CG1 3.41Å
104S89.9Confident90.5Very high35 Ų3551.6 Ų51.625%0.24529%0.292CS..SBendtrans-143.7168.6-178.872.20000111.9E106S104-E106 VanDerWaalsContact C-N 3.31Å; S104-E106 WeakPolarHBondContact CB-OE2 3.49Å; S104-E106 PolarHBondContact OG-OE2 3.36Å
105I90.1Very high90.2Very high21 Ų2147.4 Ų47.411%0.10827%0.27CS..SBendtrans-69.5-32.4178.5-73.8179.2000110.7E107 L108 F111 V387 L440I105-E107 VanDerWaalsContact C-N 3.27Å; I105-E107 PolarHBondContact O-N 3.47Å; I105-L108 HydrophobicContact CB-CD1 4.46Å; I105-L108 HydrophobicContact CG2-CD1 4.31Å; I105-L108 WeakPolarHBondContact O-CB 3.39Å; I105-L108 WeakPolarHBondContact O-CG 3.24Å; I105-L108 PolarHBondContact O-N 3.06Å; I105-F111 HydrophobicContact CG2-CE2 3.57Å; I105-F111 HydrophobicContact CG2-CZ 3.89Å; I105-F111 VanDerWaalsContact O-CD2 3.23Å; I105-F111 WeakPolarHBondContact O-CD2 3.43Å; I105-F111 WeakPolarHBondContact O-CE2 3.43Å; I105-V387 HydrophobicContact CG1-CG2 3.64Å; I105-L440 HydrophobicContact CG2-CB 4.5Å
106E88.1Confident89.3Confident73 Ų7353.3 Ų53.334%0.34130%0.296SS..THydrogen-bonded Turntrans-70.1-22.7-177.2-6293.4148.600113.6S104 L108 P453 Y454S104-E106 VanDerWaalsContact C-N 3.31Å; S104-E106 WeakPolarHBondContact CB-OE2 3.49Å; S104-E106 PolarHBondContact OG-OE2 3.36Å; E106-L108 PolarHBondContact O-N 3.35Å; E106-P453 WeakPolarHBondContact OE1-CG 3.3Å; E106-Y454 HydrophobicContact CG-CD1 4.23Å; E106-Y454 HydrophobicContact CG-CG 4.42Å; E106-Y454 WeakPolarHBondContact OE1-CD1 3.45Å
107E89.1Confident88.4Confident112 Ų11256.1 Ų56.152%0.52332%0.316SS..THydrogen-bonded Turntrans-75.1-9.1172.7-71174.3-171.700112.3P102 S103 I105P102-E107 WeakPolarHBondContact CA-OE2 3.34Å; P102-E107 HydrophobicContact CB-CB 4.08Å; S103-E107 PolarHBondContact N-OE2 2.9Å; S103-E107 VanDerWaalsContact OG-CD 3.31Å; S103-E107 PolarHBondContact OG-OE1 2.93Å; S103-E107 PolarHBondContact OG-OE2 3.17Å; I105-E107 VanDerWaalsContact C-N 3.27Å; I105-E107 PolarHBondContact O-N 3.47Å
108L91.8Very high87.5Confident2 Ų263.9 Ų63.91%0.0135%0.348CS..SBendtrans-71148.1-179.4-62.9176.3000112P102 I105 E106 A110 F111 H386 C434 L440P102-L108 HydrophobicContact CB-CD2 4.13Å; P102-L108 HydrophobicContact CG-CD2 3.71Å; I105-L108 HydrophobicContact CB-CD1 4.46Å; I105-L108 HydrophobicContact CG2-CD1 4.31Å; I105-L108 WeakPolarHBondContact O-CB 3.39Å; I105-L108 WeakPolarHBondContact O-CG 3.24Å; I105-L108 PolarHBondContact O-N 3.06Å; E106-L108 PolarHBondContact O-N 3.35Å; L108-A110 PolarHBondContact O-N 3.32Å; L108-F111 HydrophobicContact CB-CD2 4.48Å; L108-F111 PolarHBondContact O-N 2.9Å; L108-F111 VanDerWaalsContact O-N 3.11Å; L108-H386 HydrophobicContact CD1-CB 4.07Å; L108-H386 WeakPolarHBondContact CD2-O 3.43Å; L108-C434 HydrophobicContact CB-CB 4.11Å; L108-C434 HydrophobicContact CD1-CB 4.29Å; L108-C434 HydrophobicContact CD2-CB 4.01Å; L108-C434 HydrophobicContact CG-CB 4.37Å; L108-L440 HydrophobicContact CD1-CD1 4.29Å; L108-L440 HydrophobicContact CD1-CD2 3.94Å
109P91.9Very high87.2Confident41 Ų4165.5 Ų65.527%0.26635%0.347SS..G310 helixtrans-51.6-30.7-178.5-30.135.7000115.2C52 F111 S112 Y113C52-P109 HydrophobicContact CB-CG 4.33Å; P109-F111 PolarHBondContact O-N 3.47Å; P109-F111 VanDerWaalsContact O-N 3.12Å; P109-S112 CarbonylContact O-C 3.58Å; P109-S112 PolarHBondContact O-N 2.95Å; P109-S112 PolarHBondContact O-OG 3.24Å; P109-Y113 WeakPolarHBondContact O-CB 3.39Å; P109-Y113 PolarHBondContact O-N 2.96Å
110A93.4Very high87.1Confident1 Ų164 Ų641%0.00834%0.339CS..G310 helixtrans-54.5-31.9179.700000114L108 S112 C434 Q435 L440 T460L108-A110 PolarHBondContact O-N 3.32Å; A110-S112 VanDerWaalsContact C-N 3.34Å; A110-C434 WeakPolarHBondContact CA-O 3.48Å; A110-C434 VanDerWaalsContact CB-O 3.23Å; A110-C434 WeakPolarHBondContact CB-O 3.44Å; A110-C434 PolarHBondContact N-O 2.85Å; A110-Q435 WeakPolarHBondContact CA-O 3.46Å; A110-L440 HydrophobicContact CB-CD1 3.62Å; A110-T460 HydrophobicContact CB-CG2 3.88Å
111F92.2Very high87.1Confident45 Ų4569.7 Ų69.720%0.19736%0.358CS..G310 helixtrans-84.2-9.5-178.7-67.1-83.6000113.8I105 L108 P109 L440 Y454 L456 K459 T460I105-F111 HydrophobicContact CG2-CE2 3.57Å; I105-F111 HydrophobicContact CG2-CZ 3.89Å; I105-F111 VanDerWaalsContact O-CD2 3.23Å; I105-F111 WeakPolarHBondContact O-CD2 3.43Å; I105-F111 WeakPolarHBondContact O-CE2 3.43Å; L108-F111 HydrophobicContact CB-CD2 4.48Å; L108-F111 PolarHBondContact O-N 2.9Å; L108-F111 VanDerWaalsContact O-N 3.11Å; P109-F111 PolarHBondContact O-N 3.47Å; P109-F111 VanDerWaalsContact O-N 3.12Å; F111-L440 HydrophobicContact CE2-CD1 3.99Å; F111-Y454 HydrophobicContact CE1-CD2 4.49Å; F111-Y454 HydrophobicContact CE1-CG 4.41Å; F111-Y454 HydrophobicContact CZ-CD2 4.23Å; F111-Y454 HydrophobicContact CZ-CG 4.26Å; F111-L456 HydrophobicContact CZ-CD1 3.91Å; F111-K459 HydrophobicContact CD1-CB 3.95Å; F111-K459 HydrophobicContact CE1-CB 4.15Å; F111-T460 HydrophobicContact CD1-CG2 3.65Å; F111-T460 HydrophobicContact CD2-CG2 4.24Å; F111-T460 HydrophobicContact CE1-CG2 3.51Å; F111-T460 HydrophobicContact CE2-CG2 4.11Å; F111-T460 HydrophobicContact CG-CG2 4.02Å; F111-T460 HydrophobicContact CZ-CG2 3.78Å
112S90.9Very high87.2Confident82 Ų8267.7 Ų67.757%0.57335%0.353SS*.THydrogen-bonded Turntrans-1236.6175.956.50000112.6P109 A110 V114P109-S112 CarbonylContact O-C 3.58Å; P109-S112 PolarHBondContact O-N 2.95Å; P109-S112 PolarHBondContact O-OG 3.24Å; A110-S112 VanDerWaalsContact C-N 3.34Å; S112-V114 PolarHBondContact O-N 3.31Å
113Y89.8Confident87.3Confident46 Ų4671.6 Ų71.618%0.1837%0.37CS..  trans-71.3125.5-174.5177.2-125.3000111.3P109 P115 Q435 F436 Y461P109-Y113 WeakPolarHBondContact O-CB 3.39Å; P109-Y113 PolarHBondContact O-N 2.96Å; Y113-P115 HydrophobicContact CD1-CG 4.26Å; Y113-P115 HydrophobicContact CE1-CB 4.21Å; Y113-P115 HydrophobicContact CE1-CG 3.7Å; Y113-Q435 HydrophobicContact CD1-CG 3.99Å; Y113-Q435 HydrophobicContact CD2-CG 3.76Å; Y113-Q435 HydrophobicContact CE1-CG 4.12Å; Y113-Q435 HydrophobicContact CE2-CG 3.93Å; Y113-Q435 HydrophobicContact CG-CG 3.83Å; Y113-Q435 PolarHBondContact OH-NE2 3.33Å; Y113-F436 HydrophobicContact CD1-CE1 4.49Å; Y113-F436 AromaticContact CE1-CE1 3.95Å; Y113-F436 HydrophobicContact CE1-CE1 3.95Å; Y113-F436 HydrophobicContact CE1-CZ 4.44Å; Y113-Y461 AromaticContact CD1-CD2 3.74Å; Y113-Y461 HydrophobicContact CD1-CD2 3.74Å; Y113-Y461 HydrophobicContact CD1-CE2 4.31Å; Y113-Y461 HydrophobicContact CD1-CG 4.24Å; Y113-Y461 HydrophobicContact CE1-CD2 4.37Å; Y113-Y461 WeakPolarHBondContact O-CE2 3.45Å
114V86.8Confident87.4Confident114 Ų11468.2 Ų68.269%0.69134%0.344SS*.  trans-115.6111.4172.4-177.20000108.4S112S112-V114 PolarHBondContact O-N 3.31Å
115P84.5Confident87.5Confident20 Ų2066.6 Ų66.613%0.1333%0.334CS..  trans-60.9141.7177.9-21.330.3000112.7Y113 L120 Y461Y113-P115 HydrophobicContact CD1-CG 4.26Å; Y113-P115 HydrophobicContact CE1-CB 4.21Å; Y113-P115 HydrophobicContact CE1-CG 3.7Å; P115-L120 HydrophobicContact CB-CB 4.34Å; P115-L120 HydrophobicContact CB-CD2 4.17Å; P115-L120 HydrophobicContact CG-CB 4.5Å; P115-L120 HydrophobicContact CG-CD2 3.96Å; P115-L120 HydrophobicContact CG-CG 4.41Å; P115-Y461 VanDerWaalsContact CD-CZ 3.45Å; P115-Y461 WeakPolarHBondContact CD-OH 3.18Å; P115-Y461 HydrophobicContact CG-CD1 3.99Å; P115-Y461 HydrophobicContact CG-CD2 4.3Å; P115-Y461 HydrophobicContact CG-CE1 3.48Å; P115-Y461 VanDerWaalsContact CG-CE1 3.48Å; P115-Y461 HydrophobicContact CG-CE2 3.87Å; P115-Y461 HydrophobicContact CG-CG 4.37Å; P115-Y461 VanDerWaalsContact CG-CZ 3.43Å
116H75.1Confident87.6Confident145 Ų14567.1 Ų67.167%0.67133%0.334SS*.SBendtrans-70.6-35171.5-68.7-53.9000112.6M1M1-H116 WeakPolarHBondContact CE-CE1 3.5Å
117S73.2Confident87.5Confident60 Ų6070.3 Ų70.342%0.4235%0.354SS..SBendtrans-83.7127.7176.1179.50000110D119S117-D119 PolarHBondContact O-N 2.9Å; S117-D119 PolarHBondContact OG-N 3.09Å
118K73Confident87Confident204 Ų20469.2 Ų69.289%0.88735%0.351SS*.THydrogen-bonded Turntrans-70.5-10.5173.4-64.1-173.5178.2-175.90113.1
119D81.2Confident86.6Confident106 Ų10669.2 Ų69.257%0.56735%0.352SS*.THydrogen-bonded Turntrans-84.3-10.9-177.4-59.5-21.3000113.3S117 R469S117-D119 PolarHBondContact O-N 2.9Å; S117-D119 PolarHBondContact OG-N 3.09Å; D119-R469 PolarHBondContact O-NE 3.09Å; D119-R469 PolarHBondContact O-NH2 3.2Å; D119-R469 VanDerWaalsContact O-NH2 3.13Å
120L89Confident86.2Confident13 Ų1369.5 Ų69.57%0.06835%0.354CS..  trans-92.3111175.7-179.563.4000109.1P115 D124 Y461 Y466P115-L120 HydrophobicContact CB-CB 4.34Å; P115-L120 HydrophobicContact CB-CD2 4.17Å; P115-L120 HydrophobicContact CG-CB 4.5Å; P115-L120 HydrophobicContact CG-CD2 3.96Å; P115-L120 HydrophobicContact CG-CG 4.41Å; L120-D124 HydrophobicContact CD1-CB 4.08Å; L120-Y461 HydrophobicContact CD2-CD1 3.9Å; L120-Y461 HydrophobicContact CD2-CE1 4.47Å; L120-Y461 HydrophobicContact CG-CD1 3.8Å; L120-Y461 HydrophobicContact CG-CE1 4.16Å; L120-Y466 HydrophobicContact CD2-CD2 4.4Å
121R91.3Very high85.7Confident135 Ų13569.5 Ų69.551%0.50935%0.354SS..  trans-92157.1174.2-52.1176-61.7154.3-1.1110E123 D124R121-E123 VanDerWaalsContact C-N 3.28Å; R121-E123 VanDerWaalsContact CB-CD 3.47Å; R121-E123 HydrophobicContact CB-CG 4.25Å; R121-E123 WeakPolarHBondContact CB-OE2 3.37Å; R121-E123 VanDerWaalsContact CD-OE1 3.31Å; R121-E123 WeakPolarHBondContact CD-OE1 3.46Å; R121-E123 IonicContact CZ-OE1 2.83Å; R121-E123 VanDerWaalsContact CZ-OE1 3.24Å; R121-E123 IonicContact NE-OE1 3.29Å; R121-E123 PolarHBondContact NE-OE1 2.79Å; R121-E123 IonicContact NH1-OE1 2.96Å; R121-E123 PolarHBondContact NH1-OE1 2.92Å; R121-E123 PolarHBondContact O-N 3.34Å; R121-D124 IonicContact CZ-OD1 3.05Å; R121-D124 VanDerWaalsContact CZ-OD1 3.26Å; R121-D124 PolarHBondContact N-OD2 3.19Å; R121-D124 IonicContact NE-OD1 3.87Å; R121-D124 PolarHBondContact NE-OD1 2.86Å; R121-D124 IonicContact NE-OD2 3.75Å; R121-D124 IonicContact NH2-OD1 2.83Å; R121-D124 PolarHBondContact NH2-OD1 3.22Å; R121-D124 WeakPolarHBondContact O-CB 3.37Å; R121-D124 PolarHBondContact O-N 2.69Å
122Q91.2Very high85.6Confident61 Ų6169 Ų6929%0.28535%0.351SS..THydrogen-bonded Turntrans-68.7-31.5-174.7-156.9-172.1-7700112.3D124 W126 E458 Y461Q122-D124 VanDerWaalsContact C-N 3.33Å; Q122-W126 PolarHBondContact O-NE1 2.85Å; Q122-E458 PolarHBondContact NE2-O 2.78Å; Q122-Y461 VanDerWaalsContact CA-CE1 3.49Å; Q122-Y461 HydrophobicContact CB-CD1 4.28Å; Q122-Y461 HydrophobicContact CB-CE1 3.93Å; Q122-Y461 HydrophobicContact CG-CD1 4.24Å; Q122-Y461 HydrophobicContact CG-CD2 4.23Å; Q122-Y461 HydrophobicContact CG-CE1 4.17Å; Q122-Y461 HydrophobicContact CG-CE2 4.14Å; Q122-Y461 HydrophobicContact CG-CG 4.27Å
123E90.8Very high85.7Confident101 Ų10169.1 Ų69.147%0.47235%0.345SS..THydrogen-bonded Turntrans-73.1-18.8175.564.2-89.9-15700114.2R121 G125 W126R121-E123 VanDerWaalsContact C-N 3.28Å; R121-E123 VanDerWaalsContact CB-CD 3.47Å; R121-E123 HydrophobicContact CB-CG 4.25Å; R121-E123 WeakPolarHBondContact CB-OE2 3.37Å; R121-E123 VanDerWaalsContact CD-OE1 3.31Å; R121-E123 WeakPolarHBondContact CD-OE1 3.46Å; R121-E123 IonicContact CZ-OE1 2.83Å; R121-E123 VanDerWaalsContact CZ-OE1 3.24Å; R121-E123 IonicContact NE-OE1 3.29Å; R121-E123 PolarHBondContact NE-OE1 2.79Å; R121-E123 IonicContact NH1-OE1 2.96Å; R121-E123 PolarHBondContact NH1-OE1 2.92Å; R121-E123 PolarHBondContact O-N 3.34Å; E123-G125 PolarHBondContact O-N 2.74Å; E123-W126 PolarHBondContact O-N 3.4Å
124D92.3Very high86Confident15 Ų1567 Ų678%0.0834%0.337CS..THydrogen-bonded Turntrans-61.7125.4-174-72.7-15.8000110.7L120 R121 Q122 W126 S462 G465 R469L120-D124 HydrophobicContact CD1-CB 4.08Å; R121-D124 IonicContact CZ-OD1 3.05Å; R121-D124 VanDerWaalsContact CZ-OD1 3.26Å; R121-D124 PolarHBondContact N-OD2 3.19Å; R121-D124 IonicContact NE-OD1 3.87Å; R121-D124 PolarHBondContact NE-OD1 2.86Å; R121-D124 IonicContact NE-OD2 3.75Å; R121-D124 IonicContact NH2-OD1 2.83Å; R121-D124 PolarHBondContact NH2-OD1 3.22Å; R121-D124 WeakPolarHBondContact O-CB 3.37Å; R121-D124 PolarHBondContact O-N 2.69Å; Q122-D124 VanDerWaalsContact C-N 3.33Å; D124-W126 PolarHBondContact O-N 2.71Å; D124-S462 WeakPolarHBondContact O-CB 3.45Å; D124-G465 WeakPolarHBondContact O-CA 2.97Å; D124-R469 IonicContact OD1-NH2 3.09Å; D124-R469 IonicContact OD2-CZ 2.79Å; D124-R469 IonicContact OD2-NE 2.83Å; D124-R469 IonicContact OD2-NH2 2.61Å; D124-R469 PolarHBondContact OD2-NH2 3.23Å
125G92.4Very high86.5Confident2 Ų261.6 Ų61.62%0.02130%0.304CS..THydrogen-bonded Turntrans81.7-0.2174.500000116.4E123 D128 S462E123-G125 PolarHBondContact O-N 2.74Å; G125-D128 WeakPolarHBondContact CA-OD2 3.27Å; G125-S462 PolarHBondContact O-OG 2.93Å; G125-S462 VanDerWaalsContact O-OG 3.06Å
126W91.3Very high87Confident32 Ų3263.8 Ų63.812%0.12132%0.324CS..THydrogen-bonded Turntrans-76.4-42.2173.9-81.1121.5000112.5Q122 E123 D124 L456 C457 T460Q122-W126 PolarHBondContact O-NE1 2.85Å; E123-W126 PolarHBondContact O-N 3.4Å; D124-W126 PolarHBondContact O-N 2.71Å; W126-L456 HydrophobicContact CH2-CD2 4.28Å; W126-L456 HydrophobicContact CH2-CG 4.28Å; W126-C457 HydrophobicContact CD2-CB 3.98Å; W126-C457 HydrophobicContact CE3-CB 4.37Å; W126-C457 HydrophobicContact CG-CB 4.19Å; W126-T460 WeakPolarHBondContact CZ2-OG1 3.27Å; W126-T460 PolarHBondContact NE1-O 2.88Å
127D85.8Confident88Confident140 Ų14061.2 Ų61.275%0.74931%0.308SS*.SBendtrans-91.5-11.9-178.6-64.5-37.1000113.4N129D127-N129 PolarHBondContact O-N 2.89Å
128D79.3Confident89.2Confident88 Ų8859.1 Ų59.147%0.47129%0.292SS..THydrogen-bonded Turntrans-64.1-40.2-171.6-70.8-20.9000111.6G125 K363G125-D128 WeakPolarHBondContact CA-OD2 3.27Å; D128-K363 VanDerWaalsContact C-NZ 3.32Å; D128-K363 PolarHBondContact O-NZ 3.46Å
129N83.5Confident90.3Very high3 Ų351.6 Ų51.62%0.01627%0.272CS..THydrogen-bonded Turntrans-117.543.6-162.1-61.9-42.8000113.8D127 G131 K363 Q366 V367 E370 W464D127-N129 PolarHBondContact O-N 2.89Å; N129-G131 PolarHBondContact O-N 2.93Å; N129-K363 WeakPolarHBondContact OD1-CD 2.99Å; N129-K363 WeakPolarHBondContact OD1-CE 3.43Å; N129-K363 PolarHBondContact OD1-NZ 3.35Å; N129-Q366 HydrophobicContact CB-CB 4.36Å; N129-Q366 PolarHBondContact ND2-OE1 2.77Å; N129-V367 HydrophobicContact CB-CG2 4.1Å; N129-E370 HydrophobicContact CB-CG 3.98Å; N129-E370 VanDerWaalsContact O-CB 3.26Å; N129-E370 WeakPolarHBondContact O-CB 3.31Å; N129-E370 WeakPolarHBondContact O-CG 3.2Å; N129-W464 VanDerWaalsContact ND2-CD1 3.33Å; N129-W464 VanDerWaalsContact ND2-CG 3.33Å
130C82.6Confident91.1Very high46 Ų4647 Ų4731%0.31125%0.248SC..  trans-58.8121.5-179.5-178.20000111.5Y132 D133C130-Y132 PolarHBondContact O-N 2.88Å; C130-Y132 VanDerWaalsContact O-N 3.11Å; C130-D133 WeakPolarHBondContact CB-OD2 3.37Å; C130-D133 VanDerWaalsContact O-CB 3.32Å; C130-D133 WeakPolarHBondContact O-CB 3.47Å; C130-D133 PolarHBondContact O-N 2.97Å
131G82.8Confident91.5Very high1 Ų149.7 Ų49.71%0.0127%0.266CS..Hα-helixtrans-65.4-15.5179.300000113.9N129 M375N129-G131 PolarHBondContact O-N 2.93Å; G131-M375 WeakPolarHBondContact CA-SD 3.44Å
132Y92Very high91.8Very high34 Ų3445.5 Ų45.513%0.13325%0.254CS..Hα-helixtrans-71.9-28170.2-63.5-70.4000113.2C130 D134 Y135 A136 R163 F165 M375C130-Y132 PolarHBondContact O-N 2.88Å; C130-Y132 VanDerWaalsContact O-N 3.11Å; Y132-D134 PolarHBondContact O-N 3.44Å; Y132-Y135 HydrophobicContact CD1-CD2 4.32Å; Y132-Y135 PolarHBondContact O-N 3.23Å; Y132-Y135 VanDerWaalsContact O-N 3.1Å; Y132-A136 PolarHBondContact O-N 3.22Å; Y132-R163 HydrophobicContact CE1-CB 3.68Å; Y132-R163 VanDerWaalsContact CE2-NH2 3.3Å; Y132-R163 PolarHBondContact OH-N 3.19Å; Y132-F165 HydrophobicContact CD1-CE2 4.45Å; Y132-M375 HydrophobicContact CD1-CE 3.93Å; Y132-M375 HydrophobicContact CD2-CE 3.96Å; Y132-M375 HydrophobicContact CE1-CE 3.58Å; Y132-M375 HydrophobicContact CE2-CE 3.64Å; Y132-M375 HydrophobicContact CG-CE 4.11Å; Y132-M375 VanDerWaalsContact CZ-CE 3.44Å
133D91.4Very high92.1Very high86 Ų8650 Ų5046%0.4628%0.275SS..Hα-helixtrans-64.6-28.1176.8-61.9-14.4000111C130 A136 R137C130-D133 WeakPolarHBondContact CB-OD2 3.37Å; C130-D133 VanDerWaalsContact O-CB 3.32Å; C130-D133 WeakPolarHBondContact O-CB 3.47Å; C130-D133 PolarHBondContact O-N 2.97Å; D133-A136 PolarHBondContact O-N 2.88Å; D133-R137 WeakPolarHBondContact O-CB 3.5Å; D133-R137 PolarHBondContact O-N 3.49Å
134D95.9Very high92.4Very high0 Ų047.6 Ų47.60%026%0.263CS..Hα-helixtrans-66.7-38.6174.4-16036.2000112Y132 A136 R137 L138 Y359 V367 K371Y132-D134 PolarHBondContact O-N 3.44Å; D134-A136 VanDerWaalsContact C-N 3.34Å; D134-R137 WeakPolarHBondContact O-CB 3.24Å; D134-R137 PolarHBondContact O-N 3.02Å; D134-R137 IonicContact OD1-CZ 2.68Å; D134-R137 VanDerWaalsContact OD1-CZ 3.31Å; D134-R137 IonicContact OD1-NE 3.75Å; D134-R137 PolarHBondContact OD1-NE 3.26Å; D134-R137 IonicContact OD1-NH2 2.93Å; D134-R137 PolarHBondContact OD1-NH2 3.37Å; D134-L138 WeakPolarHBondContact O-CB 3.36Å; D134-L138 WeakPolarHBondContact O-CG 3.18Å; D134-L138 PolarHBondContact O-N 2.91Å; D134-Y359 VanDerWaalsContact CG-OH 3.31Å; D134-Y359 PolarHBondContact OD1-OH 3.37Å; D134-Y359 WeakPolarHBondContact OD2-CE1 3.48Å; D134-Y359 PolarHBondContact OD2-OH 3.44Å; D134-V367 HydrophobicContact CB-CG1 3.51Å; D134-K371 HydrophobicContact CB-CD 4.27Å; D134-K371 WeakPolarHBondContact OD2-CE 3.48Å; D134-K371 IonicContact OD2-NZ 3.61Å; D134-K371 PolarHBondContact OD2-NZ 2.72Å
135Y97.3Very high92.7Very high1 Ų147 Ų470%0.00426%0.26CS..Hα-helixtrans-64.4-41.7174.2-69.7-62.4000111.1Y132 R137 L138 G139 L140 F165 L190 K371 Y376Y132-Y135 HydrophobicContact CD1-CD2 4.32Å; Y132-Y135 PolarHBondContact O-N 3.23Å; Y132-Y135 VanDerWaalsContact O-N 3.1Å; Y135-R137 VanDerWaalsContact C-N 3.35Å; Y135-R137 PolarHBondContact O-N 2.82Å; Y135-L138 CarbonylContact O-C 3.53Å; Y135-L138 PolarHBondContact O-N 3.44Å; Y135-G139 PolarHBondContact O-N 3.31Å; Y135-L140 HydrophobicContact CD1-CD1 3.7Å; Y135-L140 VanDerWaalsContact O-CB 3.28Å; Y135-L140 WeakPolarHBondContact O-CB 3.49Å; Y135-L140 PolarHBondContact O-N 2.95Å; Y135-F165 VanDerWaalsContact CB-CZ 3.47Å; Y135-F165 HydrophobicContact CD1-CD1 4.43Å; Y135-F165 AromaticContact CD1-CD2 3.89Å; Y135-F165 HydrophobicContact CD1-CD2 3.89Å; Y135-F165 HydrophobicContact CD1-CE2 4.02Å; Y135-F165 HydrophobicContact CD1-CG 4.1Å; Y135-F165 HydrophobicContact CD1-CZ 4.32Å; Y135-F165 AromaticContact CD2-CD2 3.6Å; Y135-F165 HydrophobicContact CD2-CD2 3.6Å; Y135-F165 AromaticContact CD2-CE2 3.22Å; Y135-F165 HydrophobicContact CD2-CE2 3.22Å; Y135-F165 AromaticContact CD2-CZ 3.94Å; Y135-F165 HydrophobicContact CD2-CZ 3.94Å; Y135-F165 HydrophobicContact CE1-CB 4.41Å; Y135-F165 AromaticContact CE1-CD2 3.96Å; Y135-F165 HydrophobicContact CE1-CD2 3.96Å; Y135-F165 HydrophobicContact CE1-CE2 4.46Å; Y135-F165 HydrophobicContact CE1-CG 4.2Å; Y135-F165 AromaticContact CE2-CD2 3.66Å; Y135-F165 HydrophobicContact CE2-CD2 3.66Å; Y135-F165 AromaticContact CE2-CE2 3.75Å; Y135-F165 HydrophobicContact CE2-CE2 3.75Å; Y135-F165 AromaticContact CG-CD2 3.72Å; Y135-F165 HydrophobicContact CG-CD2 3.72Å; Y135-F165 HydrophobicContact CG-CE1 4.27Å; Y135-F165 AromaticContact CG-CE2 3.38Å; Y135-F165 HydrophobicContact CG-CE2 3.38Å; Y135-F165 HydrophobicContact CG-CG 4.3Å; Y135-F165 AromaticContact CG-CZ 3.67Å; Y135-F165 HydrophobicContact CG-CZ 3.67Å; Y135-F165 AromaticContact CZ-CD2 3.84Å; Y135-L190 PolarHBondContact OH-O 2.83Å; Y135-K371 HydrophobicContact CE1-CD 4.39Å; Y135-K371 HydrophobicContact CE2-CD 3.98Å; Y135-K371 HydrophobicContact CE2-CG 4.43Å; Y135-Y376 WeakPolarHBondContact OH-CE2 3.38Å; Y135-Y376 PolarHBondContact OH-OH 3.06Å
136A95.1Very high93Very high66 Ų6648 Ų4855%0.54527%0.267SS..Hα-helixtrans-60.3-44.5174.500000111.6Y132 D133 D134 L138 G139Y132-A136 PolarHBondContact O-N 3.22Å; D133-A136 PolarHBondContact O-N 2.88Å; D134-A136 VanDerWaalsContact C-N 3.34Å; A136-L138 VanDerWaalsContact C-N 3.28Å; A136-L138 PolarHBondContact O-N 3.01Å; A136-G139 PolarHBondContact O-N 3.45Å
137R96.7Very high93.2Very high91 Ų9149.9 Ų49.934%0.34328%0.279SS..Hα-helixtrans-59.3-37.3174.5-175.3-166.267.688.4-4.9112.6D133 D134 Y135 G139 D356 Y358 Y359D133-R137 WeakPolarHBondContact O-CB 3.5Å; D133-R137 PolarHBondContact O-N 3.49Å; D134-R137 WeakPolarHBondContact O-CB 3.24Å; D134-R137 PolarHBondContact O-N 3.02Å; D134-R137 IonicContact OD1-CZ 2.68Å; D134-R137 VanDerWaalsContact OD1-CZ 3.31Å; D134-R137 IonicContact OD1-NE 3.75Å; D134-R137 PolarHBondContact OD1-NE 3.26Å; D134-R137 IonicContact OD1-NH2 2.93Å; D134-R137 PolarHBondContact OD1-NH2 3.37Å; Y135-R137 VanDerWaalsContact C-N 3.35Å; Y135-R137 PolarHBondContact O-N 2.82Å; R137-G139 PolarHBondContact O-N 2.97Å; R137-D356 IonicContact CZ-OD2 2.66Å; R137-D356 VanDerWaalsContact CZ-OD2 3.31Å; R137-D356 IonicContact NH1-OD1 3.64Å; R137-D356 IonicContact NH1-OD2 3.65Å; R137-D356 PolarHBondContact NH1-OD2 3.22Å; R137-D356 IonicContact NH2-OD2 3.94Å; R137-D356 PolarHBondContact NH2-OD2 2.69Å; R137-Y358 VanDerWaalsContact NE-CE1 3.3Å; R137-Y359 PolarHBondContact NH2-OH 2.85Å
138L97.6Very high93.8Very high17 Ų1744.2 Ų44.29%0.08925%0.25CS..THydrogen-bonded Turntrans-74.43.3175.1-67.4172000113.3D134 Y135 A136 L140 Y192D134-L138 WeakPolarHBondContact O-CB 3.36Å; D134-L138 WeakPolarHBondContact O-CG 3.18Å; D134-L138 PolarHBondContact O-N 2.91Å; Y135-L138 CarbonylContact O-C 3.53Å; Y135-L138 PolarHBondContact O-N 3.44Å; A136-L138 VanDerWaalsContact C-N 3.28Å; A136-L138 PolarHBondContact O-N 3.01Å; L138-L140 HydrophobicContact CB-CD1 3.82Å; L138-L140 HydrophobicContact CB-CG 4.33Å; L138-L140 HydrophobicContact CD1-CD1 4.4Å; L138-Y192 HydrophobicContact CD1-CD2 4.13Å; L138-Y192 HydrophobicContact CD2-CD2 3.9Å; L138-Y192 HydrophobicContact CD2-CE2 3.66Å
139G97.3Very high94.5Very high45 Ų4545.7 Ų45.746%0.46425%0.254SS..THydrogen-bonded Turntrans7437.418000000112.8Y135 A136 R137 N142Y135-G139 PolarHBondContact O-N 3.31Å; A136-G139 PolarHBondContact O-N 3.45Å; R137-G139 PolarHBondContact O-N 2.97Å; G139-N142 WeakPolarHBondContact O-CB 3.29Å; G139-N142 PolarHBondContact O-ND2 3.47Å
140L97.5Very high95.1Very high11 Ų1147 Ų476%0.05826%0.261CS..  trans-118.3149-178.9-59.9157.2000111.3Y135 L138 W145 F165 L190 L193Y135-L140 HydrophobicContact CD1-CD1 3.7Å; Y135-L140 VanDerWaalsContact O-CB 3.28Å; Y135-L140 WeakPolarHBondContact O-CB 3.49Å; Y135-L140 PolarHBondContact O-N 2.95Å; L138-L140 HydrophobicContact CB-CD1 3.82Å; L138-L140 HydrophobicContact CB-CG 4.33Å; L138-L140 HydrophobicContact CD1-CD1 4.4Å; L140-W145 HydrophobicContact CD2-CB 3.45Å; L140-W145 VanDerWaalsContact CD2-CB 3.45Å; L140-W145 HydrophobicContact CD2-CG 3.89Å; L140-F165 HydrophobicContact CB-CD1 4.09Å; L140-F165 HydrophobicContact CB-CE1 3.67Å; L140-L190 HydrophobicContact CD1-CD2 3.42Å; L140-L190 VanDerWaalsContact CD1-CD2 3.42Å; L140-L190 HydrophobicContact CD2-CD2 3.88Å; L140-L190 HydrophobicContact CG-CD2 4.32Å; L140-L193 HydrophobicContact CD1-CB 4.42Å; L140-L193 HydrophobicContact CD2-CD2 3.98Å; L140-L193 HydrophobicContact CG-CD2 4.3Å
141P97.5Very high95.8Very high69 Ų6945 Ų4545%0.44825%0.247SC..SBendcis-67.9158.3-6.230.8-35.9000112.4W145 I147 F165P141-W145 WeakPolarHBondContact CA-O 3.45Å; P141-W145 VanDerWaalsContact CB-O 3.3Å; P141-W145 WeakPolarHBondContact CB-O 3.5Å; P141-I147 HydrophobicContact CB-CG1 4.42Å; P141-I147 HydrophobicContact CG-CD1 4.29Å; P141-I147 HydrophobicContact CG-CG1 4.37Å; P141-F165 HydrophobicContact CB-CE1 4.37Å
142N97.4Very high96.4Very high46 Ų4649.7 Ų49.725%0.24627%0.267CS..  trans-143.2-171.617963.627.6000111.2G139 K144 W145 R168G139-N142 WeakPolarHBondContact O-CB 3.29Å; G139-N142 PolarHBondContact O-ND2 3.47Å; N142-K144 PolarHBondContact O-N 3.13Å; N142-K144 PolarHBondContact OD1-N 3.17Å; N142-W145 PolarHBondContact N-O 3.2Å; N142-W145 PolarHBondContact O-N 2.88Å; N142-W145 PolarHBondContact OD1-N 3.16Å; N142-R168 PolarHBondContact O-NE 2.85Å; N142-R168 PolarHBondContact O-NH2 3.3Å
143E96.9Very high96.4Very high156 Ų15652.7 Ų52.773%0.72929%0.286SS*.SBendtrans-54.4-23.4-178.7-61-61.3166.800114.4R168E143-R168 VanDerWaalsContact O-CD 3.3Å; E143-R168 WeakPolarHBondContact O-CD 3.39Å
144K97.9Very high96.5Very high51 Ų5149.4 Ų49.422%0.22227%0.268CS..SBendtrans-110.6-22.6-174.3-60.3-176.1176.1173.90114.1N142 P167 R168 E198 T228 P230N142-K144 PolarHBondContact O-N 3.13Å; N142-K144 PolarHBondContact OD1-N 3.17Å; K144-P167 CarbonylContact O-C 3.51Å; K144-P167 WeakPolarHBondContact O-CA 3.41Å; K144-R168 PolarHBondContact O-N 3.37Å; K144-E198 WeakPolarHBondContact CE-OE1 3.4Å; K144-E198 IonicContact NZ-OE1 3.18Å; K144-E198 PolarHBondContact NZ-OE1 3.37Å; K144-E198 IonicContact NZ-OE2 2.75Å; K144-E198 PolarHBondContact NZ-OE2 3.07Å; K144-T228 HydrophobicContact CB-CG2 4.36Å; K144-T228 WeakPolarHBondContact CD-O 3.1Å; K144-T228 PolarHBondContact NZ-O 3.13Å; K144-P230 VanDerWaalsContact NZ-CD 3.34Å
145W98.4Very high96.4Very high3 Ų355.6 Ų55.61%0.01130%0.296CS..EExtended strand (participates in β ladder)trans-128.1132.6-175.8-68.295.1000111L140 P141 N142 V166 P167 L190 V200 C202 I225 T228L140-W145 HydrophobicContact CD2-CB 3.45Å; L140-W145 VanDerWaalsContact CD2-CB 3.45Å; L140-W145 HydrophobicContact CD2-CG 3.89Å; P141-W145 WeakPolarHBondContact CA-O 3.45Å; P141-W145 VanDerWaalsContact CB-O 3.3Å; P141-W145 WeakPolarHBondContact CB-O 3.5Å; N142-W145 PolarHBondContact N-O 3.2Å; N142-W145 PolarHBondContact O-N 2.88Å; N142-W145 PolarHBondContact OD1-N 3.16Å; W145-V166 WeakPolarHBondContact CA-O 3.32Å; W145-P167 HydrophobicContact CH2-CG 4.12Å; W145-P167 HydrophobicContact CZ3-CG 3.97Å; W145-L190 HydrophobicContact CB-CD2 4.4Å; W145-L190 HydrophobicContact CD2-CB 4.4Å; W145-L190 HydrophobicContact CD2-CD1 4.28Å; W145-L190 HydrophobicContact CD2-CD2 3.7Å; W145-L190 HydrophobicContact CD2-CG 4.36Å; W145-L190 HydrophobicContact CE3-CB 3.73Å; W145-L190 HydrophobicContact CE3-CD1 4.33Å; W145-L190 HydrophobicContact CE3-CD2 3.81Å; W145-L190 HydrophobicContact CE3-CG 4.18Å; W145-L190 HydrophobicContact CG-CD2 3.95Å; W145-L190 HydrophobicContact CH2-CB 4.17Å; W145-L190 HydrophobicContact CH2-CD1 3.93Å; W145-L190 HydrophobicContact CZ2-CD1 3.84Å; W145-L190 HydrophobicContact CZ3-CB 3.6Å; W145-L190 HydrophobicContact CZ3-CD1 4.17Å; W145-L190 HydrophobicContact CZ3-CD2 4.4Å; W145-L190 HydrophobicContact CZ3-CG 4.27Å; W145-V200 HydrophobicContact CH2-CG2 4.37Å; W145-V200 HydrophobicContact CZ2-CB 4.16Å; W145-V200 HydrophobicContact CZ2-CG1 3.75Å; W145-V200 HydrophobicContact CZ2-CG2 3.79Å; W145-C202 VanDerWaalsContact CH2-SG 3.55Å; W145-I225 HydrophobicContact CH2-CG1 4.3Å; W145-I225 HydrophobicContact CH2-CG2 4.44Å; W145-T228 HydrophobicContact CD2-CG2 4.37Å; W145-T228 HydrophobicContact CH2-CG2 4.35Å; W145-T228 HydrophobicContact CZ2-CG2 3.68Å; W145-T228 VanDerWaalsContact CZ2-OG1 3.26Å; W145-T228 WeakPolarHBondContact CZ2-OG1 2.89Å
146A98.1Very high96.3Very high21 Ų2160.1 Ų60.117%0.17431%0.314CS..EExtended strand (participates in β ladder)trans-125.9155.4179.400000111.3F165 V166 R168A146-F165 WeakPolarHBondContact O-CA 3.35Å; A146-V166 PolarHBondContact N-O 2.87Å; A146-V166 PolarHBondContact O-N 3.33Å; A146-R168 HydrophobicContact CB-CB 4.08Å; A146-R168 HydrophobicContact CB-CG 4.23Å
147I97.4Very high96.3Very high73 Ų7357.2 Ų57.237%0.37429%0.29SS..EExtended strand (participates in β ladder)trans-76.6130168.1-58173.9000107.4P141 R163 F165P141-I147 HydrophobicContact CB-CG1 4.42Å; P141-I147 HydrophobicContact CG-CD1 4.29Å; P141-I147 HydrophobicContact CG-CG1 4.37Å; I147-R163 HydrophobicContact CG2-CB 3.86Å; I147-R163 HydrophobicContact CG2-CG 4.16Å; I147-F165 HydrophobicContact CD1-CE1 4.22Å; I147-F165 HydrophobicContact CD1-CZ 3.83Å; I147-F165 HydrophobicContact CG1-CD1 4.13Å; I147-F165 HydrophobicContact CG1-CE1 3.46Å; I147-F165 VanDerWaalsContact CG1-CE1 3.46Å; I147-F165 HydrophobicContact CG1-CE2 3.98Å; I147-F165 HydrophobicContact CG1-CZ 3.39Å
148S97.1Very high96.2Very high21 Ų2158.3 Ų58.315%0.14730%0.299CS..EExtended strand (participates in β ladder)trans-109.3128.6170.2177.60000109.9L150 I164S148-L150 PolarHBondContact O-N 3.04Å; S148-L150 VanDerWaalsContact OG-CB 3.24Å; S148-L150 WeakPolarHBondContact OG-CB 3.18Å; S148-L150 PolarHBondContact OG-N 3.48Å; S148-I164 PolarHBondContact N-O 3.15Å; S148-I164 PolarHBondContact O-N 3.44Å
149E95Very high96Very high118 Ų11858.2 Ų58.255%0.55130%0.302SS*.  trans-85.314.4169.8-66.3-166.9-167.500112.3N151 K152E149-N151 PolarHBondContact O-N 3.37Å; E149-N151 VanDerWaalsContact O-N 3.13Å; E149-K152 HydrophobicContact CB-CB 4.49Å; E149-K152 VanDerWaalsContact O-CB 3.23Å; E149-K152 WeakPolarHBondContact O-CB 3.42Å; E149-K152 PolarHBondContact O-N 3.35Å; E149-K152 IonicContact OE2-NZ 3.48Å; E149-K152 PolarHBondContact OE2-NZ 3.04Å
150L96.2Very high96Very high31 Ų3156.1 Ų56.116%0.16228%0.28CS..THydrogen-bonded Turntrans-53.4-36.9-179.4178.866.5000112.2S148 Y156 L175 I176 L179S148-L150 PolarHBondContact O-N 3.04Å; S148-L150 VanDerWaalsContact OG-CB 3.24Å; S148-L150 WeakPolarHBondContact OG-CB 3.18Å; S148-L150 PolarHBondContact OG-N 3.48Å; L150-Y156 HydrophobicContact CD1-CD2 4.13Å; L150-Y156 HydrophobicContact CD1-CE2 3.76Å; L150-Y156 HydrophobicContact CG-CD2 4.17Å; L150-Y156 HydrophobicContact CG-CE2 4.3Å; L150-Y156 WeakPolarHBondContact O-CD2 3.25Å; L150-Y156 VanDerWaalsContact O-CE2 3.3Å; L150-Y156 WeakPolarHBondContact O-CE2 3.46Å; L150-L175 HydrophobicContact CD2-CB 3.57Å; L150-L175 HydrophobicContact CD2-CD1 4.14Å; L150-L175 HydrophobicContact CD2-CG 4.48Å; L150-I176 HydrophobicContact CD1-CD1 4.34Å; L150-I176 HydrophobicContact CD1-CG1 3.95Å; L150-L179 HydrophobicContact CD2-CD2 3.89Å
151N96.2Very high95.9Very high4 Ų455.6 Ų55.62%0.02128%0.278CS..THydrogen-bonded Turntrans-97.220.5-178.6-162.145.6000113.6E149 F154 Y156 C157 Y160 P161 E162E149-N151 PolarHBondContact O-N 3.37Å; E149-N151 VanDerWaalsContact O-N 3.13Å; N151-F154 VanDerWaalsContact O-CA 3.31Å; N151-F154 WeakPolarHBondContact O-CA 3.3Å; N151-F154 PolarHBondContact O-N 2.84Å; N151-Y156 PolarHBondContact OD1-N 3.23Å; N151-C157 PolarHBondContact ND2-O 2.57Å; N151-C157 PolarHBondContact OD1-N 3.06Å; N151-C157 PolarHBondContact OD1-O 3.27Å; N151-Y160 PolarHBondContact ND2-O 3.04Å; N151-P161 PolarHBondContact ND2-O 2.71Å; N151-E162 CarbonylContact C-O 3.56Å; N151-E162 VanDerWaalsContact C-O 3.27Å; N151-E162 WeakPolarHBondContact O-CA 2.96Å
152K95Very high95.8Very high99 Ų9954.9 Ų54.943%0.4327%0.268SS..G310 helixtrans-51.4141174.5-171.8176.3-162.7152.60110.7E149 F154 E155 E162E149-K152 HydrophobicContact CB-CB 4.49Å; E149-K152 VanDerWaalsContact O-CB 3.23Å; E149-K152 WeakPolarHBondContact O-CB 3.42Å; E149-K152 PolarHBondContact O-N 3.35Å; E149-K152 IonicContact OE2-NZ 3.48Å; E149-K152 PolarHBondContact OE2-NZ 3.04Å; K152-F154 PolarHBondContact O-N 3.04Å; K152-E155 WeakPolarHBondContact O-CG 3.16Å; K152-E155 PolarHBondContact O-N 3.45Å; K152-E162 PolarHBondContact N-O 2.95Å
153N92.7Very high95.7Very high98 Ų9857.9 Ų57.952%0.52428%0.276SS..G310 helixtrans53.718.3-172.9-46.4-55.4000114.5E155 E162N153-E155 VanDerWaalsContact C-N 3.27Å; N153-E155 HydrophobicContact CB-CG 4.33Å; N153-E155 PolarHBondContact ND2-OE1 3.45Å; N153-E155 PolarHBondContact O-N 2.86Å; N153-E162 WeakPolarHBondContact CA-OE1 3.07Å; N153-E162 PolarHBondContact N-OE1 2.82Å
154F94Very high95.7Very high17 Ų1750.5 Ų50.58%0.07524%0.242CC..G310 helixtrans62.327.6-178.3-48.9-83.3000114.7N151 K152 Y156 Y160 E162 H444 K445 L448N151-F154 VanDerWaalsContact O-CA 3.31Å; N151-F154 WeakPolarHBondContact O-CA 3.3Å; N151-F154 PolarHBondContact O-N 2.84Å; K152-F154 PolarHBondContact O-N 3.04Å; F154-Y156 VanDerWaalsContact C-N 3.28Å; F154-Y156 PolarHBondContact O-N 2.72Å; F154-Y160 VanDerWaalsContact CD1-O 3.27Å; F154-Y160 WeakPolarHBondContact CD1-O 3.47Å; F154-Y160 WeakPolarHBondContact CE1-O 3.35Å; F154-E162 HydrophobicContact CD1-CG 4.32Å; F154-E162 HydrophobicContact CD2-CG 4.21Å; F154-E162 HydrophobicContact CE1-CG 3.9Å; F154-E162 HydrophobicContact CE2-CG 3.75Å; F154-E162 HydrophobicContact CG-CG 4.47Å; F154-E162 HydrophobicContact CZ-CG 3.58Å; F154-H444 HydrophobicContact CE1-CB 4.19Å; F154-H444 AromaticContact CE1-CD2 3.91Å; F154-H444 AromaticContact CZ-CD2 3.82Å; F154-K445 HydrophobicContact CB-CB 4.39Å; F154-K445 HydrophobicContact CB-CD 3.84Å; F154-K445 HydrophobicContact CB-CG 4.26Å; F154-K445 HydrophobicContact CD1-CB 3.7Å; F154-K445 HydrophobicContact CD1-CG 4.37Å; F154-K445 HydrophobicContact CD2-CB 3.71Å; F154-K445 HydrophobicContact CD2-CD 4.08Å; F154-K445 HydrophobicContact CD2-CG 3.57Å; F154-K445 HydrophobicContact CE1-CB 3.79Å; F154-K445 HydrophobicContact CE2-CB 3.83Å; F154-K445 HydrophobicContact CE2-CG 3.97Å; F154-K445 HydrophobicContact CG-CB 3.65Å; F154-K445 HydrophobicContact CG-CD 3.95Å; F154-K445 HydrophobicContact CG-CG 3.8Å; F154-K445 HydrophobicContact CZ-CB 3.86Å; F154-L448 HydrophobicContact CZ-CD1 4.21Å
155E93.9Very high95.7Very high129 Ų12948.2 Ų48.260%0.60323%0.232SC*.SBendtrans-59.7-31-171.7-76.9172.8-161.300114.7K152 N153K152-E155 WeakPolarHBondContact O-CG 3.16Å; K152-E155 PolarHBondContact O-N 3.45Å; N153-E155 VanDerWaalsContact C-N 3.27Å; N153-E155 HydrophobicContact CB-CG 4.33Å; N153-E155 PolarHBondContact ND2-OE1 3.45Å; N153-E155 PolarHBondContact O-N 2.86Å
156Y94.7Very high95.7Very high96 Ų9648.3 Ų48.338%0.37623%0.233SC..SBendtrans-112-30.6-174.7-69-87.1000113.9L150 N151 F154 L179L150-Y156 HydrophobicContact CD1-CD2 4.13Å; L150-Y156 HydrophobicContact CD1-CE2 3.76Å; L150-Y156 HydrophobicContact CG-CD2 4.17Å; L150-Y156 HydrophobicContact CG-CE2 4.3Å; L150-Y156 WeakPolarHBondContact O-CD2 3.25Å; L150-Y156 VanDerWaalsContact O-CE2 3.3Å; L150-Y156 WeakPolarHBondContact O-CE2 3.46Å; N151-Y156 PolarHBondContact OD1-N 3.23Å; F154-Y156 VanDerWaalsContact C-N 3.28Å; F154-Y156 PolarHBondContact O-N 2.72Å; Y156-L179 HydrophobicContact CD1-CD1 3.84Å; Y156-L179 HydrophobicContact CD1-CD2 3.71Å; Y156-L179 HydrophobicContact CD1-CG 4.47Å; Y156-L179 HydrophobicContact CE1-CD2 4.44Å; Y156-L179 HydrophobicContact CG-CD1 4.47Å; Y156-L179 HydrophobicContact CG-CD2 3.91Å
157C96Very high95.8Very high6 Ų647.6 Ų47.64%0.04123%0.226CC..  trans-148.9101.2-178.2-172.70000111.2N151 G159 Y160 R184 R186N151-C157 PolarHBondContact ND2-O 2.57Å; N151-C157 PolarHBondContact OD1-N 3.06Å; N151-C157 PolarHBondContact OD1-O 3.27Å; C157-G159 PolarHBondContact O-N 2.94Å; C157-Y160 HydrophobicContact CB-CG 4.42Å; C157-Y160 PolarHBondContact O-N 2.91Å; C157-Y160 VanDerWaalsContact O-N 3.14Å; C157-R184 PolarHBondContact SG-O 3.37Å; C157-R186 WeakPolarHBondContact SG-CG 3.31Å
158E93.8Very high95.8Very high113 Ų11349.2 Ų49.253%0.52823%0.227SC..THydrogen-bonded Turntrans-62.5-24.7178-58.9-175.8144.100113.9Y160 K445E158-Y160 VanDerWaalsContact C-N 3.34Å; E158-K445 HydrophobicContact CB-CD 4.06Å; E158-K445 HydrophobicContact CG-CD 3.95Å; E158-K445 IonicContact OE1-NZ 3.58Å; E158-K445 PolarHBondContact OE1-NZ 2.78Å
159G93.7Very high95.8Very high16 Ų1655.2 Ų55.217%0.16525%0.253CS..THydrogen-bonded Turntrans-84.3-4.7179.100000114.4C157 R186 Y376 G377C157-G159 PolarHBondContact O-N 2.94Å; G159-R186 PolarHBondContact O-NH1 3.47Å; G159-Y376 CarbonylContact O-C 3.59Å; G159-G377 PolarHBondContact O-N 2.96Å
160Y97.1Very high95.9Very high1 Ų150.4 Ų50.40%0.00423%0.231CC..SBendtrans-107.1157.4176.5-85.99.9000110.5N151 F154 C157 E158 I164 R186 L187 V189 R203 C204 Y376N151-Y160 PolarHBondContact ND2-O 3.04Å; F154-Y160 VanDerWaalsContact CD1-O 3.27Å; F154-Y160 WeakPolarHBondContact CD1-O 3.47Å; F154-Y160 WeakPolarHBondContact CE1-O 3.35Å; C157-Y160 HydrophobicContact CB-CG 4.42Å; C157-Y160 PolarHBondContact O-N 2.91Å; C157-Y160 VanDerWaalsContact O-N 3.14Å; E158-Y160 VanDerWaalsContact C-N 3.34Å; Y160-I164 HydrophobicContact CD2-CG2 4.16Å; Y160-R186 HydrophobicContact CD1-CG 4.05Å; Y160-R186 HydrophobicContact CE1-CB 3.77Å; Y160-R186 HydrophobicContact CE1-CG 3.74Å; Y160-R186 HydrophobicContact CE2-CB 4.39Å; Y160-R186 PolarHBondContact OH-O 2.79Å; Y160-L187 HydrophobicContact CD2-CD2 3.98Å; Y160-L187 HydrophobicContact CE2-CD2 3.75Å; Y160-L187 VanDerWaalsContact CE2-O 3.23Å; Y160-L187 WeakPolarHBondContact CE2-O 3.37Å; Y160-L187 PolarHBondContact OH-O 3.09Å; Y160-V189 HydrophobicContact CD2-CG1 4.29Å; Y160-V189 HydrophobicContact CE2-CB 4.41Å; Y160-V189 HydrophobicContact CE2-CG1 3.74Å; Y160-V189 HydrophobicContact CE2-CG2 3.73Å; Y160-R203 PolarHBondContact OH-O 3.05Å; Y160-C204 WeakPolarHBondContact OH-CA 3.32Å; Y160-Y376 AromaticContact CD1-CD1 3.64Å; Y160-Y376 HydrophobicContact CD1-CD1 3.64Å; Y160-Y376 HydrophobicContact CD1-CE1 4.21Å; Y160-Y376 AromaticContact CE1-CD1 3.81Å; Y160-Y376 HydrophobicContact CE1-CD1 3.81Å; Y160-Y376 HydrophobicContact CE1-CE1 4.35Å; Y160-Y376 HydrophobicContact CG-CD1 4.16Å; Y160-Y376 HydrophobicContact CG-CE1 4.33Å
161P95.5Very high96Very high0 Ų052 Ų520%024%0.244CC..  trans-67.5163.6171.530.5-34.1000111N151 R163 I164 M375 Y376N151-P161 PolarHBondContact ND2-O 2.71Å; P161-R163 VanDerWaalsContact C-N 3.31Å; P161-R163 PolarHBondContact O-N 2.82Å; P161-I164 HydrophobicContact CG-CG2 4.24Å; P161-M375 HydrophobicContact CB-CB 4.29Å; P161-M375 HydrophobicContact CB-CE 3.92Å; P161-M375 WeakPolarHBondContact CD-O 3.21Å; P161-M375 HydrophobicContact CG-CB 4.45Å; P161-M375 HydrophobicContact CG-CE 4.15Å; P161-Y376 VanDerWaalsContact CD-CE1 3.5Å; P161-Y376 HydrophobicContact CG-CD1 4.34Å; P161-Y376 HydrophobicContact CG-CE1 3.92Å
162E94.3Very high96Very high53 Ų5353.7 Ų53.725%0.24826%0.262CS..SBendtrans-62.1-39.9180-65.9-173.495.800112.9N151 K152 N153 F154N151-E162 CarbonylContact C-O 3.56Å; N151-E162 VanDerWaalsContact C-O 3.27Å; N151-E162 WeakPolarHBondContact O-CA 2.96Å; K152-E162 PolarHBondContact N-O 2.95Å; N153-E162 WeakPolarHBondContact CA-OE1 3.07Å; N153-E162 PolarHBondContact N-OE1 2.82Å; F154-E162 HydrophobicContact CD1-CG 4.32Å; F154-E162 HydrophobicContact CD2-CG 4.21Å; F154-E162 HydrophobicContact CE1-CG 3.9Å; F154-E162 HydrophobicContact CE2-CG 3.75Å; F154-E162 HydrophobicContact CG-CG 4.47Å; F154-E162 HydrophobicContact CZ-CG 3.58Å
163R95.8Very high96.2Very high109 Ų10953.6 Ų53.641%0.41127%0.271SS..SBendtrans-104.5120.9178.9-64.1-179.2-65-173.7-0.1109.1Y132 I147 P161Y132-R163 HydrophobicContact CE1-CB 3.68Å; Y132-R163 VanDerWaalsContact CE2-NH2 3.3Å; Y132-R163 PolarHBondContact OH-N 3.19Å; I147-R163 HydrophobicContact CG2-CB 3.86Å; I147-R163 HydrophobicContact CG2-CG 4.16Å; P161-R163 VanDerWaalsContact C-N 3.31Å; P161-R163 PolarHBondContact O-N 2.82Å
164I97.4Very high96.5Very high1 Ų149.8 Ų49.81%0.00525%0.252CS..EExtended strand (participates in β ladder)trans-118.8148.218058.2175.5000110.7S148 Y160 P161 V166 L187 V189S148-I164 PolarHBondContact N-O 3.15Å; S148-I164 PolarHBondContact O-N 3.44Å; Y160-I164 HydrophobicContact CD2-CG2 4.16Å; P161-I164 HydrophobicContact CG-CG2 4.24Å; I164-V166 HydrophobicContact CD1-CG1 4.26Å; I164-V166 HydrophobicContact CG1-CG1 4.3Å; I164-L187 HydrophobicContact CD1-CD2 4.05Å; I164-V189 HydrophobicContact CB-CG1 3.93Å; I164-V189 HydrophobicContact CD1-CG1 3.98Å; I164-V189 HydrophobicContact CG1-CG1 4.42Å; I164-V189 HydrophobicContact CG2-CG1 4.31Å
165F98.2Very high96.7Very high4 Ų449.3 Ų49.32%0.01825%0.25CC..EExtended strand (participates in β ladder)trans-97.7124.3178.2-77.3-102.3000110.8Y132 Y135 L140 P141 A146 I147 L190Y132-F165 HydrophobicContact CD1-CE2 4.45Å; Y135-F165 VanDerWaalsContact CB-CZ 3.47Å; Y135-F165 HydrophobicContact CD1-CD1 4.43Å; Y135-F165 AromaticContact CD1-CD2 3.89Å; Y135-F165 HydrophobicContact CD1-CD2 3.89Å; Y135-F165 HydrophobicContact CD1-CE2 4.02Å; Y135-F165 HydrophobicContact CD1-CG 4.1Å; Y135-F165 HydrophobicContact CD1-CZ 4.32Å; Y135-F165 AromaticContact CD2-CD2 3.6Å; Y135-F165 HydrophobicContact CD2-CD2 3.6Å; Y135-F165 AromaticContact CD2-CE2 3.22Å; Y135-F165 HydrophobicContact CD2-CE2 3.22Å; Y135-F165 AromaticContact CD2-CZ 3.94Å; Y135-F165 HydrophobicContact CD2-CZ 3.94Å; Y135-F165 HydrophobicContact CE1-CB 4.41Å; Y135-F165 AromaticContact CE1-CD2 3.96Å; Y135-F165 HydrophobicContact CE1-CD2 3.96Å; Y135-F165 HydrophobicContact CE1-CE2 4.46Å; Y135-F165 HydrophobicContact CE1-CG 4.2Å; Y135-F165 AromaticContact CE2-CD2 3.66Å; Y135-F165 HydrophobicContact CE2-CD2 3.66Å; Y135-F165 AromaticContact CE2-CE2 3.75Å; Y135-F165 HydrophobicContact CE2-CE2 3.75Å; Y135-F165 AromaticContact CG-CD2 3.72Å; Y135-F165 HydrophobicContact CG-CD2 3.72Å; Y135-F165 HydrophobicContact CG-CE1 4.27Å; Y135-F165 AromaticContact CG-CE2 3.38Å; Y135-F165 HydrophobicContact CG-CE2 3.38Å; Y135-F165 HydrophobicContact CG-CG 4.3Å; Y135-F165 AromaticContact CG-CZ 3.67Å; Y135-F165 HydrophobicContact CG-CZ 3.67Å; Y135-F165 AromaticContact CZ-CD2 3.84Å; L140-F165 HydrophobicContact CB-CD1 4.09Å; L140-F165 HydrophobicContact CB-CE1 3.67Å; P141-F165 HydrophobicContact CB-CE1 4.37Å; A146-F165 WeakPolarHBondContact O-CA 3.35Å; I147-F165 HydrophobicContact CD1-CE1 4.22Å; I147-F165 HydrophobicContact CD1-CZ 3.83Å; I147-F165 HydrophobicContact CG1-CD1 4.13Å; I147-F165 HydrophobicContact CG1-CE1 3.46Å; I147-F165 VanDerWaalsContact CG1-CE1 3.46Å; I147-F165 HydrophobicContact CG1-CE2 3.98Å; I147-F165 HydrophobicContact CG1-CZ 3.39Å; F165-L190 HydrophobicContact CB-CB 3.81Å; F165-L190 HydrophobicContact CB-CD2 4.26Å; F165-L190 PolarHBondContact O-N 3.12Å
166V98.7Very high96.9Very high5 Ų545.4 Ų45.43%0.0323%0.233CC..EExtended strand (participates in β ladder)trans-134.1162.1-176-60.80000110.2W145 A146 I164 R168 V170 L175 V189W145-V166 WeakPolarHBondContact CA-O 3.32Å; A146-V166 PolarHBondContact N-O 2.87Å; A146-V166 PolarHBondContact O-N 3.33Å; I164-V166 HydrophobicContact CD1-CG1 4.26Å; I164-V166 HydrophobicContact CG1-CG1 4.3Å; V166-R168 PolarHBondContact O-N 2.85Å; V166-V170 HydrophobicContact CB-CG1 4.17Å; V166-V170 HydrophobicContact CG2-CG1 3.92Å; V166-L175 HydrophobicContact CB-CD2 4.25Å; V166-L175 HydrophobicContact CG1-CD2 3.96Å; V166-L175 HydrophobicContact CG2-CD1 4.22Å; V166-V189 HydrophobicContact CG1-CG1 4.44Å
167P98.6Very high97.1Very high5 Ų541.5 Ų41.53%0.03222%0.222CC..EExtended strand (participates in β ladder)trans-56.2130.9174.6-25.935.7000111.2K144 W145 H169 V170 H224 I225 T228K144-P167 CarbonylContact O-C 3.51Å; K144-P167 WeakPolarHBondContact O-CA 3.41Å; W145-P167 HydrophobicContact CH2-CG 4.12Å; W145-P167 HydrophobicContact CZ3-CG 3.97Å; P167-H169 PolarHBondContact O-N 2.99Å; P167-H169 VanDerWaalsContact O-N 3.08Å; P167-V170 WeakPolarHBondContact O-CG1 3.33Å; P167-V170 PolarHBondContact O-N 2.86Å; P167-V170 VanDerWaalsContact O-N 3.09Å; P167-H224 HydrophobicContact CB-CB 3.95Å; P167-H224 HydrophobicContact CG-CB 4.02Å; P167-I225 HydrophobicContact CG-CG1 3.76Å; P167-T228 HydrophobicContact CB-CG2 3.87Å; P167-T228 HydrophobicContact CG-CG2 4.09Å
168R98.4Very high97.2Very high107 Ų10741.2 Ų41.240%0.40422%0.22SC..THydrogen-bonded Turntrans-52.9-37.8-171.2175.5175.7-69.9-101.2-2.3113.9N142 E143 K144 A146 V166N142-R168 PolarHBondContact O-NE 2.85Å; N142-R168 PolarHBondContact O-NH2 3.3Å; E143-R168 VanDerWaalsContact O-CD 3.3Å; E143-R168 WeakPolarHBondContact O-CD 3.39Å; K144-R168 PolarHBondContact O-N 3.37Å; A146-R168 HydrophobicContact CB-CB 4.08Å; A146-R168 HydrophobicContact CB-CG 4.23Å; V166-R168 PolarHBondContact O-N 2.85Å
169H96.8Very high97.4Very high147 Ų14736.4 Ų36.468%0.68120%0.198SC*.THydrogen-bonded Turntrans-96.811.5-173.6-57.8-60.1000114.2P167 P171P167-H169 PolarHBondContact O-N 2.99Å; P167-H169 VanDerWaalsContact O-N 3.08Å; H169-P171 WeakPolarHBondContact O-CD 3.44Å
170V98.1Very high97.6Very high17 Ų1742.7 Ų42.710%0.10322%0.221CC..  trans-74127.4177.171.80000110.8V166 P167 V174 L175 L221 H224V166-V170 HydrophobicContact CB-CG1 4.17Å; V166-V170 HydrophobicContact CG2-CG1 3.92Å; P167-V170 WeakPolarHBondContact O-CG1 3.33Å; P167-V170 PolarHBondContact O-N 2.86Å; P167-V170 VanDerWaalsContact O-N 3.09Å; V170-V174 HydrophobicContact CG2-CB 3.94Å; V170-V174 HydrophobicContact CG2-CG1 3.69Å; V170-L175 HydrophobicContact CG1-CD1 3.95Å; V170-L175 HydrophobicContact CG1-CD2 3.72Å; V170-L175 HydrophobicContact CG1-CG 3.87Å; V170-L175 HydrophobicContact CG2-CD2 4.13Å; V170-L175 HydrophobicContact CG2-CG 4.31Å; V170-L221 HydrophobicContact CG2-CD1 3.98Å; V170-H224 HydrophobicContact CB-CB 4.41Å; V170-H224 HydrophobicContact CG2-CB 4.46Å
171P97.6Very high97.6Very high66 Ų6643.6 Ų43.643%0.42923%0.225SC..  trans-67.2143.6176-21.833.8000112.5H169 V174 L175H169-P171 WeakPolarHBondContact O-CD 3.44Å; P171-V174 HydrophobicContact CB-CG2 4.16Å; P171-V174 HydrophobicContact CG-CG2 4.19Å; P171-V174 VanDerWaalsContact O-CB 3.3Å; P171-V174 WeakPolarHBondContact O-CB 3.47Å; P171-V174 PolarHBondContact O-N 3.41Å; P171-L175 PolarHBondContact O-N 3.22Å
172G96.7Very high97.7Very high39 Ų3943.7 Ų43.740%0.40223%0.225SC..Hα-helixtrans-50.4-45.917700000115V174 L175 I176G172-V174 PolarHBondContact O-N 3.1Å; G172-L175 WeakPolarHBondContact O-CB 3.32Å; G172-L175 PolarHBondContact O-N 2.91Å; G172-L175 VanDerWaalsContact O-N 3.1Å; G172-I176 PolarHBondContact O-N 2.62Å; G172-I176 VanDerWaalsContact O-N 3.09Å
173P98.1Very high97.9Very high96 Ų9641.4 Ų41.462%0.62322%0.215SC*.Hα-helixtrans-58.6-30.8176.3-27.936.4000114.4I176 G177P173-I176 PolarHBondContact O-N 3.1Å; P173-G177 PolarHBondContact O-N 3Å
174V98.6Very high97.9Very high19 Ų1943.8 Ų43.812%0.11522%0.224CC..Hα-helixtrans-68-40.9177173.30000110.7V170 P171 G172 G177 S178 E217 L221V170-V174 HydrophobicContact CG2-CB 3.94Å; V170-V174 HydrophobicContact CG2-CG1 3.69Å; P171-V174 HydrophobicContact CB-CG2 4.16Å; P171-V174 HydrophobicContact CG-CG2 4.19Å; P171-V174 VanDerWaalsContact O-CB 3.3Å; P171-V174 WeakPolarHBondContact O-CB 3.47Å; P171-V174 PolarHBondContact O-N 3.41Å; G172-V174 PolarHBondContact O-N 3.1Å; V174-G177 PolarHBondContact O-N 2.98Å; V174-S178 WeakPolarHBondContact O-CB 3.48Å; V174-S178 PolarHBondContact O-N 3.43Å; V174-E217 HydrophobicContact CG1-CB 4.49Å; V174-E217 VanDerWaalsContact CG1-O 3.24Å; V174-E217 WeakPolarHBondContact CG1-O 3.27Å; V174-L221 HydrophobicContact CG1-CB 4.06Å
175L98.5Very high97.9Very high6 Ų644.2 Ų44.23%0.03123%0.228CC..Hα-helixtrans-64.2-43.2174.7-61.9175.3000111.6L150 V166 V170 P171 G172 S178 L179 L187 L221L150-L175 HydrophobicContact CD2-CB 3.57Å; L150-L175 HydrophobicContact CD2-CD1 4.14Å; L150-L175 HydrophobicContact CD2-CG 4.48Å; V166-L175 HydrophobicContact CB-CD2 4.25Å; V166-L175 HydrophobicContact CG1-CD2 3.96Å; V166-L175 HydrophobicContact CG2-CD1 4.22Å; V170-L175 HydrophobicContact CG1-CD1 3.95Å; V170-L175 HydrophobicContact CG1-CD2 3.72Å; V170-L175 HydrophobicContact CG1-CG 3.87Å; V170-L175 HydrophobicContact CG2-CD2 4.13Å; V170-L175 HydrophobicContact CG2-CG 4.31Å; P171-L175 PolarHBondContact O-N 3.22Å; G172-L175 WeakPolarHBondContact O-CB 3.32Å; G172-L175 PolarHBondContact O-N 2.91Å; G172-L175 VanDerWaalsContact O-N 3.1Å; L175-S178 PolarHBondContact O-N 2.66Å; L175-L179 PolarHBondContact O-N 2.82Å; L175-L187 HydrophobicContact CB-CD1 4.14Å; L175-L187 HydrophobicContact CD2-CD1 3.9Å; L175-L221 HydrophobicContact CD2-CD1 3.94Å; L175-L221 HydrophobicContact CD2-CD2 4.35Å
176I98.2Very high97.9Very high47 Ų4744 Ų4424%0.24123%0.227CC..Hα-helixtrans-66.4-37.8179.4-64.4168.4000111.8L150 G172 P173 L179 K180L150-I176 HydrophobicContact CD1-CD1 4.34Å; L150-I176 HydrophobicContact CD1-CG1 3.95Å; G172-I176 PolarHBondContact O-N 2.62Å; G172-I176 VanDerWaalsContact O-N 3.09Å; P173-I176 PolarHBondContact O-N 3.1Å; I176-L179 WeakPolarHBondContact O-CG 3.24Å; I176-K180 HydrophobicContact CG2-CD 4.39Å; I176-K180 VanDerWaalsContact O-CG 3.32Å; I176-K180 WeakPolarHBondContact O-CG 3.34Å; I176-K180 PolarHBondContact O-N 3.41Å
177G98.3Very high97.9Very high14 Ų1444 Ų4414%0.14423%0.227CC..Hα-helixtrans-66.7-47174.100000111.9P173 V174 L179 K180 F181P173-G177 PolarHBondContact O-N 3Å; V174-G177 PolarHBondContact O-N 2.98Å; G177-L179 PolarHBondContact O-N 3.09Å; G177-K180 PolarHBondContact O-N 3.08Å; G177-F181 PolarHBondContact O-N 2.82Å; G177-F181 VanDerWaalsContact O-N 3.15Å
178S98.5Very high97.9Very high0 Ų043.8 Ų43.80%023%0.225CC..Hα-helixtrans-61.2-45.9178.6176.60000112.5V174 L175 K180 F181 R182 D218 L221V174-S178 WeakPolarHBondContact O-CB 3.48Å; V174-S178 PolarHBondContact O-N 3.43Å; L175-S178 PolarHBondContact O-N 2.66Å; S178-K180 VanDerWaalsContact C-N 3.28Å; S178-K180 PolarHBondContact O-N 3.02Å; S178-F181 CarbonylContact O-C 3.59Å; S178-F181 PolarHBondContact O-N 3.23Å; S178-R182 WeakPolarHBondContact O-CG 3.42Å; S178-R182 PolarHBondContact O-N 3.46Å; S178-R182 VanDerWaalsContact O-N 3.08Å; S178-D218 PolarHBondContact OG-OD1 3.43Å; S178-L221 WeakPolarHBondContact OG-CD2 3.42Å
179L97.6Very high97.9Very high12 Ų1238.7 Ų38.76%0.06321%0.206CC..Hα-helixtrans-61.1-38179.173.985.9000111.9L150 Y156 L175 I176 G177 F181 R182 G185 L187L150-L179 HydrophobicContact CD2-CD2 3.89Å; Y156-L179 HydrophobicContact CD1-CD1 3.84Å; Y156-L179 HydrophobicContact CD1-CD2 3.71Å; Y156-L179 HydrophobicContact CD1-CG 4.47Å; Y156-L179 HydrophobicContact CE1-CD2 4.44Å; Y156-L179 HydrophobicContact CG-CD1 4.47Å; Y156-L179 HydrophobicContact CG-CD2 3.91Å; L175-L179 PolarHBondContact O-N 2.82Å; I176-L179 WeakPolarHBondContact O-CG 3.24Å; G177-L179 PolarHBondContact O-N 3.09Å; L179-F181 PolarHBondContact O-N 3.31Å; L179-R182 PolarHBondContact O-N 3.28Å; L179-G185 VanDerWaalsContact O-CA 3.3Å; L179-G185 WeakPolarHBondContact O-CA 3.33Å; L179-L187 HydrophobicContact CB-CB 4.09Å; L179-L187 HydrophobicContact CB-CD1 4.39Å; L179-L187 HydrophobicContact CB-CD2 4.28Å; L179-L187 HydrophobicContact CB-CG 4.49Å
180K97.8Very high98Very high149 Ų14931.7 Ų31.765%0.64817%0.174SC*.Hα-helixtrans-67.5-28.4177.4-72.7175.6-178.9-179.90112.2I176 G177 S178I176-K180 HydrophobicContact CG2-CD 4.39Å; I176-K180 VanDerWaalsContact O-CG 3.32Å; I176-K180 WeakPolarHBondContact O-CG 3.34Å; I176-K180 PolarHBondContact O-N 3.41Å; G177-K180 PolarHBondContact O-N 3.08Å; S178-K180 VanDerWaalsContact C-N 3.28Å; S178-K180 PolarHBondContact O-N 3.02Å
181F98Very high98.1Very high20 Ų2030.9 Ų30.99%0.08817%0.169CC..Hα-helixtrans-86.4-6.4177.6-169.4-116.3000113.6G177 S178 L179 P207 L208 A209 A213 C215 D218G177-F181 PolarHBondContact O-N 2.82Å; G177-F181 VanDerWaalsContact O-N 3.15Å; S178-F181 CarbonylContact O-C 3.59Å; S178-F181 PolarHBondContact O-N 3.23Å; L179-F181 PolarHBondContact O-N 3.31Å; F181-P207 HydrophobicContact CD1-CB 3.89Å; F181-P207 HydrophobicContact CE1-CB 3.44Å; F181-P207 VanDerWaalsContact CE1-CB 3.44Å; F181-P207 HydrophobicContact CZ-CB 4.09Å; F181-P207 CarbonylContact O-C 3.54Å; F181-P207 WeakPolarHBondContact O-CA 3.45Å; F181-L208 HydrophobicContact CD2-CB 4.35Å; F181-L208 WeakPolarHBondContact CE2-O 3.48Å; F181-L208 WeakPolarHBondContact O-CB 3.46Å; F181-L208 WeakPolarHBondContact O-CG 3.34Å; F181-L208 PolarHBondContact O-N 3.33Å; F181-A209 HydrophobicContact CZ-CB 3.91Å; F181-A213 HydrophobicContact CE2-CB 4.26Å; F181-C215 HydrophobicContact CB-CB 3.72Å; F181-C215 HydrophobicContact CD1-CB 3.45Å; F181-C215 VanDerWaalsContact CD1-CB 3.45Å; F181-C215 HydrophobicContact CD2-CB 3.65Å; F181-C215 HydrophobicContact CE1-CB 3.86Å; F181-C215 HydrophobicContact CE2-CB 4.06Å; F181-C215 HydrophobicContact CG-CB 3.31Å; F181-C215 HydrophobicContact CZ-CB 4.14Å; F181-D218 HydrophobicContact CD1-CB 3.79Å; F181-D218 HydrophobicContact CE1-CB 4.49Å
182R97.9Very high98.1Very high2 Ų228 Ų281%0.00815%0.15CC..BIsolated β-bridgetrans-106.7138.9-176.9-68.1-83.7176.1-179.7-9.2110.2S178 L179 R184 G185 S205 D218 E257S178-R182 WeakPolarHBondContact O-CG 3.42Å; S178-R182 PolarHBondContact O-N 3.46Å; S178-R182 VanDerWaalsContact O-N 3.08Å; L179-R182 PolarHBondContact O-N 3.28Å; R182-R184 PolarHBondContact O-N 3.17Å; R182-G185 PolarHBondContact O-N 2.82Å; R182-S205 WeakPolarHBondContact CD-O 3.29Å; R182-S205 PolarHBondContact NH1-O 2.62Å; R182-D218 IonicContact CZ-OD1 3.97Å; R182-D218 IonicContact CZ-OD2 3.54Å; R182-D218 IonicContact NE-OD1 3.24Å; R182-D218 PolarHBondContact NE-OD1 3.33Å; R182-D218 IonicContact NE-OD2 3.8Å; R182-D218 IonicContact NH2-OD1 2.87Å; R182-D218 PolarHBondContact NH2-OD1 3.16Å; R182-D218 IonicContact NH2-OD2 2.82Å; R182-D218 PolarHBondContact NH2-OD2 2.93Å; R182-E257 IonicContact CZ-OE1 2.95Å; R182-E257 IonicContact NH1-OE1 3.4Å; R182-E257 PolarHBondContact NH1-OE1 2.93Å; R182-E257 IonicContact NH2-OE1 3.26Å; R182-E257 PolarHBondContact NH2-OE1 3.42Å
183S97.5Very high98.2Very high5 Ų526.9 Ų26.94%0.03513%0.134CC..G310 helixtrans-52.8120.5-179.6-167.30000109.9G185 R186 S205 Q206 D339S183-G185 VanDerWaalsContact C-N 3.3Å; S183-G185 PolarHBondContact O-N 3.24Å; S183-R186 PolarHBondContact O-N 3.29Å; S183-S205 PolarHBondContact N-OG 3.05Å; S183-S205 WeakPolarHBondContact O-CB 3.31Å; S183-S205 PolarHBondContact O-OG 2.81Å; S183-Q206 PolarHBondContact N-O 3.3Å; S183-D339 PolarHBondContact OG-OD1 2.81Å
184R96.6Very high98.2Very high159 Ų15922.9 Ų22.960%0.611%0.107SC*.G310 helixtrans59.930.7179.4-54.5175.8175.9-104.29114.9C157 R182 R186 D339 W341C157-R184 PolarHBondContact SG-O 3.37Å; R182-R184 PolarHBondContact O-N 3.17Å; R184-R186 PolarHBondContact O-N 2.96Å; R184-D339 IonicContact NE-OD1 2.72Å; R184-W341 VanDerWaalsContact CZ-CH2 3.49Å
185G97.6Very high98Very high9 Ų926.9 Ų26.99%0.09314%0.135CC..G310 helixtrans77.33.2175.300000114.7L179 R182 S183 L187L179-G185 VanDerWaalsContact O-CA 3.3Å; L179-G185 WeakPolarHBondContact O-CA 3.33Å; R182-G185 PolarHBondContact O-N 2.82Å; S183-G185 VanDerWaalsContact C-N 3.3Å; S183-G185 PolarHBondContact O-N 3.24Å; G185-L187 VanDerWaalsContact C-N 3.26Å; G185-L187 WeakPolarHBondContact O-CD2 3.35Å; G185-L187 PolarHBondContact O-N 3.19Å
186R98.4Very high97.8Very high1 Ų132.3 Ų32.30%0.00416%0.159CC..  trans-83.270.3-171.3-65.2172.571.687.6-1.8111.3C157 G159 Y160 S183 R184 C204 S205 D339 G340 Y376C157-R186 WeakPolarHBondContact SG-CG 3.31Å; G159-R186 PolarHBondContact O-NH1 3.47Å; Y160-R186 HydrophobicContact CD1-CG 4.05Å; Y160-R186 HydrophobicContact CE1-CB 3.77Å; Y160-R186 HydrophobicContact CE1-CG 3.74Å; Y160-R186 HydrophobicContact CE2-CB 4.39Å; Y160-R186 PolarHBondContact OH-O 2.79Å; S183-R186 PolarHBondContact O-N 3.29Å; R184-R186 PolarHBondContact O-N 2.96Å; R186-C204 WeakPolarHBondContact O-CA 3.44Å; R186-C204 VanDerWaalsContact O-CB 3.28Å; R186-C204 WeakPolarHBondContact O-CB 3.49Å; R186-S205 PolarHBondContact O-N 3.35Å; R186-S205 PolarHBondContact O-OG 3.17Å; R186-D339 WeakPolarHBondContact CD-O 3.38Å; R186-D339 PolarHBondContact NE-O 3.48Å; R186-G340 PolarHBondContact NH2-O 3.13Å; R186-Y376 PolarHBondContact NH1-O 2.87Å; R186-Y376 PolarHBondContact NH2-O 2.85Å
187L98.5Very high97.7Very high4 Ų431 Ų312%0.02115%0.152CC..  trans-61159.7176.976.7169.5000113.4Y160 I164 L175 L179 G185 V189 L221Y160-L187 HydrophobicContact CD2-CD2 3.98Å; Y160-L187 HydrophobicContact CE2-CD2 3.75Å; Y160-L187 VanDerWaalsContact CE2-O 3.23Å; Y160-L187 WeakPolarHBondContact CE2-O 3.37Å; Y160-L187 PolarHBondContact OH-O 3.09Å; I164-L187 HydrophobicContact CD1-CD2 4.05Å; L175-L187 HydrophobicContact CB-CD1 4.14Å; L175-L187 HydrophobicContact CD2-CD1 3.9Å; L179-L187 HydrophobicContact CB-CB 4.09Å; L179-L187 HydrophobicContact CB-CD1 4.39Å; L179-L187 HydrophobicContact CB-CD2 4.28Å; L179-L187 HydrophobicContact CB-CG 4.49Å; G185-L187 VanDerWaalsContact C-N 3.26Å; G185-L187 WeakPolarHBondContact O-CD2 3.35Å; G185-L187 PolarHBondContact O-N 3.19Å; L187-V189 HydrophobicContact CD2-CG1 4.19Å; L187-V189 HydrophobicContact CG-CG1 4.16Å; L187-V189 PolarHBondContact O-N 2.84Å; L187-L221 HydrophobicContact CD1-CD2 4.42Å
188P98.7Very high97.6Very high0 Ų033.5 Ų33.50%016%0.16CC..  trans-53.9121.3168.9-2734.5000113.3R203 C204 L221 M222 I225P188-R203 WeakPolarHBondContact CA-O 3.46Å; P188-C204 HydrophobicContact CB-CB 4.4Å; P188-C204 HydrophobicContact CG-CB 4.03Å; P188-L221 HydrophobicContact CB-CD2 3.95Å; P188-L221 HydrophobicContact CB-CG 4.38Å; P188-L221 HydrophobicContact CG-CD2 3.96Å; P188-M222 HydrophobicContact CB-CE 4.38Å; P188-M222 HydrophobicContact CG-CE 3.49Å; P188-M222 VanDerWaalsContact CG-CE 3.49Å; P188-M222 HydrophobicContact CG-SD 4.24Å; P188-I225 HydrophobicContact CB-CD1 3.52Å
189V98.7Very high97.6Very high1 Ų133.5 Ų33.51%0.00616%0.16CC..EExtended strand (participates in β ladder)trans-136.7154.3176.4-64.80000110Y160 I164 V166 L187 C202 R203 Y376Y160-V189 HydrophobicContact CD2-CG1 4.29Å; Y160-V189 HydrophobicContact CE2-CB 4.41Å; Y160-V189 HydrophobicContact CE2-CG1 3.74Å; Y160-V189 HydrophobicContact CE2-CG2 3.73Å; I164-V189 HydrophobicContact CB-CG1 3.93Å; I164-V189 HydrophobicContact CD1-CG1 3.98Å; I164-V189 HydrophobicContact CG1-CG1 4.42Å; I164-V189 HydrophobicContact CG2-CG1 4.31Å; V166-V189 HydrophobicContact CG1-CG1 4.44Å; L187-V189 HydrophobicContact CD2-CG1 4.19Å; L187-V189 HydrophobicContact CG-CG1 4.16Å; L187-V189 PolarHBondContact O-N 2.84Å; V189-C202 CarbonylContact O-C 3.46Å; V189-C202 WeakPolarHBondContact O-CA 3.48Å; V189-C202 VanDerWaalsContact O-CB 3.28Å; V189-C202 WeakPolarHBondContact O-CB 3.42Å; V189-R203 HydrophobicContact CG2-CG 3.84Å; V189-R203 PolarHBondContact N-O 3.36Å; V189-R203 PolarHBondContact O-N 2.96Å; V189-Y376 HydrophobicContact CG2-CE1 3.66Å
190L98.7Very high97.6Very high0 Ų033 Ų330%016%0.157CC..EExtended strand (participates in β ladder)trans-66.9134.7177.6-173.764.5000111.2Y135 L140 W145 F165 Y192 V200Y135-L190 PolarHBondContact OH-O 2.83Å; L140-L190 HydrophobicContact CD1-CD2 3.42Å; L140-L190 VanDerWaalsContact CD1-CD2 3.42Å; L140-L190 HydrophobicContact CD2-CD2 3.88Å; L140-L190 HydrophobicContact CG-CD2 4.32Å; W145-L190 HydrophobicContact CB-CD2 4.4Å; W145-L190 HydrophobicContact CD2-CB 4.4Å; W145-L190 HydrophobicContact CD2-CD1 4.28Å; W145-L190 HydrophobicContact CD2-CD2 3.7Å; W145-L190 HydrophobicContact CD2-CG 4.36Å; W145-L190 HydrophobicContact CE3-CB 3.73Å; W145-L190 HydrophobicContact CE3-CD1 4.33Å; W145-L190 HydrophobicContact CE3-CD2 3.81Å; W145-L190 HydrophobicContact CE3-CG 4.18Å; W145-L190 HydrophobicContact CG-CD2 3.95Å; W145-L190 HydrophobicContact CH2-CB 4.17Å; W145-L190 HydrophobicContact CH2-CD1 3.93Å; W145-L190 HydrophobicContact CZ2-CD1 3.84Å; W145-L190 HydrophobicContact CZ3-CB 3.6Å; W145-L190 HydrophobicContact CZ3-CD1 4.17Å; W145-L190 HydrophobicContact CZ3-CD2 4.4Å; W145-L190 HydrophobicContact CZ3-CG 4.27Å; F165-L190 HydrophobicContact CB-CB 3.81Å; F165-L190 HydrophobicContact CB-CD2 4.26Å; F165-L190 PolarHBondContact O-N 3.12Å; L190-Y192 WeakPolarHBondContact CD1-O 3.31Å; L190-V200 HydrophobicContact CD1-CB 3.64Å; L190-V200 HydrophobicContact CD1-CG1 3.68Å; L190-V200 HydrophobicContact CD1-CG2 4.42Å
191S98.6Very high97.7Very high0 Ų025.9 Ų25.90%013%0.127CC..EExtended strand (participates in β ladder)trans-107.4-44.2166.4-82.80000111.5I201 R203 K371 E372S191-I201 WeakPolarHBondContact CA-O 3.25Å; S191-I201 WeakPolarHBondContact CB-O 3.47Å; S191-I201 PolarHBondContact N-O 3.09Å; S191-R203 WeakPolarHBondContact OG-CD 3.3Å; S191-R203 VanDerWaalsContact OG-CG 3.28Å; S191-R203 WeakPolarHBondContact OG-CG 3.33Å; S191-K371 PolarHBondContact O-NZ 3.34Å; S191-E372 VanDerWaalsContact CB-OE1 3.27Å; S191-E372 WeakPolarHBondContact CB-OE1 3.26Å; S191-E372 PolarHBondContact OG-OE1 3.14Å; S191-E372 VanDerWaalsContact OG-OE1 3.07Å; S191-E372 PolarHBondContact OG-OE2 2.87Å; S191-E372 VanDerWaalsContact OG-OE2 3.06Å
192Y98.7Very high97.7Very high6 Ų624.9 Ų24.92%0.02412%0.122CC..EExtended strand (participates in β ladder)trans-147.4142.2-172.2179.9-102.1000111.8L138 L190 Y194 V200 I201 L355 D356 Y359L138-Y192 HydrophobicContact CD1-CD2 4.13Å; L138-Y192 HydrophobicContact CD2-CD2 3.9Å; L138-Y192 HydrophobicContact CD2-CE2 3.66Å; L190-Y192 WeakPolarHBondContact CD1-O 3.31Å; Y192-Y194 AromaticContact CE1-CD2 3.89Å; Y192-Y194 HydrophobicContact CE1-CD2 3.89Å; Y192-Y194 HydrophobicContact CE1-CG 4.4Å; Y192-Y194 WeakPolarHBondContact OH-CD2 3.36Å; Y192-V200 CarbonylContact O-C 3.59Å; Y192-V200 VanDerWaalsContact O-CA 3.27Å; Y192-V200 WeakPolarHBondContact O-CA 3.48Å; Y192-V200 WeakPolarHBondContact O-CB 3.42Å; Y192-I201 HydrophobicContact CD1-CD1 4.12Å; Y192-I201 HydrophobicContact CD1-CG1 4.36Å; Y192-I201 PolarHBondContact N-O 3.5Å; Y192-I201 PolarHBondContact O-N 2.93Å; Y192-L355 HydrophobicContact CD1-CD1 4.15Å; Y192-L355 HydrophobicContact CE1-CB 4.1Å; Y192-L355 HydrophobicContact CE1-CD1 3.91Å; Y192-D356 HydrophobicContact CE2-CB 4.07Å; Y192-D356 WeakPolarHBondContact OH-CB 3.37Å; Y192-Y359 AromaticContact CD2-CE2 3.87Å; Y192-Y359 HydrophobicContact CD2-CE2 3.87Å; Y192-Y359 AromaticContact CE2-CE2 3.73Å; Y192-Y359 HydrophobicContact CE2-CE2 3.73Å
193L98.5Very high97.8Very high15 Ų1524.8 Ų24.88%0.07912%0.122CC..EExtended strand (participates in β ladder)trans-119.5120.4174.7171.263.5000109.2L140 S195 V200L140-L193 HydrophobicContact CD1-CB 4.42Å; L140-L193 HydrophobicContact CD2-CD2 3.98Å; L140-L193 HydrophobicContact CG-CD2 4.3Å; L193-S195 PolarHBondContact O-N 3.02Å; L193-V200 HydrophobicContact CB-CG1 4.41Å; L193-V200 HydrophobicContact CD1-CG1 3.58Å
194Y98Very high97.8Very high12 Ų1224.6 Ų24.65%0.04712%0.12CC..  trans-84.599.8174.7-164-120.9000110Y192 K196 N197 E198 A199 V327 L355 L487Y192-Y194 AromaticContact CE1-CD2 3.89Å; Y192-Y194 HydrophobicContact CE1-CD2 3.89Å; Y192-Y194 HydrophobicContact CE1-CG 4.4Å; Y192-Y194 WeakPolarHBondContact OH-CD2 3.36Å; Y194-K196 HydrophobicContact CD1-CB 4.1Å; Y194-K196 HydrophobicContact CE1-CB 3.75Å; Y194-K196 HydrophobicContact CE1-CD 4.11Å; Y194-K196 HydrophobicContact CE1-CG 4.25Å; Y194-K196 PolarHBondContact O-N 3.37Å; Y194-N197 WeakPolarHBondContact CD1-OD1 3.39Å; Y194-N197 PolarHBondContact O-N 3.4Å; Y194-E198 PolarHBondContact O-N 2.94Å; Y194-A199 WeakPolarHBondContact CB-O 3.39Å; Y194-A199 PolarHBondContact N-O 3.48Å; Y194-V327 HydrophobicContact CD1-CG1 4.47Å; Y194-V327 HydrophobicContact CG-CG1 4.03Å; Y194-L355 HydrophobicContact CD2-CD2 4.19Å; Y194-L355 HydrophobicContact CE2-CD2 4.08Å; Y194-L487 HydrophobicContact CE2-CD2 4.35Å; Y194-L487 WeakPolarHBondContact OH-CD2 3.25Å
195S93.9Very high97.9Very high102 Ų10217 Ų1771%0.7139%0.092SC*.THydrogen-bonded Turntrans-59.4-20.7-171.458.10000114.9L193L193-S195 PolarHBondContact O-N 3.02Å
196K94.3Very high97.9Very high120 Ų12016.6 Ų16.652%0.5229%0.087SC..THydrogen-bonded Turntrans-74.4-27.9-177.8-63.5-177.2-173.2165.70114Y194Y194-K196 HydrophobicContact CD1-CB 4.1Å; Y194-K196 HydrophobicContact CE1-CB 3.75Å; Y194-K196 HydrophobicContact CE1-CD 4.11Å; Y194-K196 HydrophobicContact CE1-CG 4.25Å; Y194-K196 PolarHBondContact O-N 3.37Å
197N96.5Very high97.9Very high20 Ų2016.5 Ų16.511%0.1079%0.087CC..THydrogen-bonded Turntrans-143.77.5-175.16817.3000114.1Y194 A199 V327 S328 G330Y194-N197 WeakPolarHBondContact CD1-OD1 3.39Å; Y194-N197 PolarHBondContact O-N 3.4Å; N197-A199 PolarHBondContact O-N 2.77Å; N197-A199 VanDerWaalsContact O-N 3.12Å; N197-A199 WeakPolarHBondContact OD1-CB 3.38Å; N197-A199 PolarHBondContact OD1-N 2.85Å; N197-V327 PolarHBondContact ND2-O 2.82Å; N197-S328 PolarHBondContact ND2-O 2.9Å; N197-S328 VanDerWaalsContact ND2-O 3.16Å; N197-G330 VanDerWaalsContact ND2-CA 3.3Å; N197-G330 WeakPolarHBondContact ND2-CA 3.48Å; N197-G330 PolarHBondContact ND2-N 3.21Å
198E96.4Very high97.8Very high67 Ų6719.4 Ų19.431%0.31310%0.102SC..  trans65.96.5178.8-43-175.1101.300115.7K144 Y194K144-E198 WeakPolarHBondContact CE-OE1 3.4Å; K144-E198 IonicContact NZ-OE1 3.18Å; K144-E198 PolarHBondContact NZ-OE1 3.37Å; K144-E198 IonicContact NZ-OE2 2.75Å; K144-E198 PolarHBondContact NZ-OE2 3.07Å; Y194-E198 PolarHBondContact O-N 2.94Å
199A98.5Very high97.6Very high0 Ų020 Ų200%011%0.107CC..  trans-66.4145.9170.900000110.7Y194 N197 V327Y194-A199 WeakPolarHBondContact CB-O 3.39Å; Y194-A199 PolarHBondContact N-O 3.48Å; N197-A199 PolarHBondContact O-N 2.77Å; N197-A199 VanDerWaalsContact O-N 3.12Å; N197-A199 WeakPolarHBondContact OD1-CB 3.38Å; N197-A199 PolarHBondContact OD1-N 2.85Å; A199-V327 HydrophobicContact CB-CG1 3.99Å; A199-V327 WeakPolarHBondContact CB-O 3.48Å
200V98.8Very high97.3Very high0 Ų020.4 Ų20.40%011%0.111CC..EExtended strand (participates in β ladder)trans-125156.9-175.9-630000112.5W145 L190 Y192 L193 I225 S332 V333W145-V200 HydrophobicContact CH2-CG2 4.37Å; W145-V200 HydrophobicContact CZ2-CB 4.16Å; W145-V200 HydrophobicContact CZ2-CG1 3.75Å; W145-V200 HydrophobicContact CZ2-CG2 3.79Å; L190-V200 HydrophobicContact CD1-CB 3.64Å; L190-V200 HydrophobicContact CD1-CG1 3.68Å; L190-V200 HydrophobicContact CD1-CG2 4.42Å; Y192-V200 CarbonylContact O-C 3.59Å; Y192-V200 VanDerWaalsContact O-CA 3.27Å; Y192-V200 WeakPolarHBondContact O-CA 3.48Å; Y192-V200 WeakPolarHBondContact O-CB 3.42Å; L193-V200 HydrophobicContact CB-CG1 4.41Å; L193-V200 HydrophobicContact CD1-CG1 3.58Å; V200-I225 HydrophobicContact CG2-CG2 4.38Å; V200-S332 PolarHBondContact N-OG 3.29Å; V200-S332 CarbonylContact O-C 2.76Å; V200-S332 WeakPolarHBondContact O-CA 3.33Å; V200-V333 PolarHBondContact O-N 3.08Å
201I98.9Very high96.9Very high0 Ų027.7 Ų27.70%014%0.143CC..EExtended strand (participates in β ladder)trans-107.8121.1159.6-53.9172.5000107.2S191 Y192 I323 V327 V333 V335 V348 A351 L355S191-I201 WeakPolarHBondContact CA-O 3.25Å; S191-I201 WeakPolarHBondContact CB-O 3.47Å; S191-I201 PolarHBondContact N-O 3.09Å; Y192-I201 HydrophobicContact CD1-CD1 4.12Å; Y192-I201 HydrophobicContact CD1-CG1 4.36Å; Y192-I201 PolarHBondContact N-O 3.5Å; Y192-I201 PolarHBondContact O-N 2.93Å; I201-I323 HydrophobicContact CD1-CG2 3.72Å; I201-I323 HydrophobicContact CG1-CG2 3.98Å; I201-I323 HydrophobicContact CG2-CG2 4.49Å; I201-V327 HydrophobicContact CD1-CG2 4.31Å; I201-V327 HydrophobicContact CG1-CG2 3.68Å; I201-V333 CarbonylContact C-O 3.49Å; I201-V333 WeakPolarHBondContact CA-O 3.16Å; I201-V335 HydrophobicContact CG2-CG2 3.95Å; I201-V348 HydrophobicContact CG2-CG1 4.17Å; I201-V348 HydrophobicContact CG2-CG2 4.03Å; I201-A351 HydrophobicContact CD1-CB 4Å; I201-L355 HydrophobicContact CD1-CD1 3.75Å
202C98.9Very high96.5Very high0 Ų032.7 Ų32.70%018%0.178CC..EExtended strand (participates in β ladder)trans-106.2154.9167.6-69.10000110.1W145 V189 I225 V333 V334 V335W145-C202 VanDerWaalsContact CH2-SG 3.55Å; V189-C202 CarbonylContact O-C 3.46Å; V189-C202 WeakPolarHBondContact O-CA 3.48Å; V189-C202 VanDerWaalsContact O-CB 3.28Å; V189-C202 WeakPolarHBondContact O-CB 3.42Å; C202-I225 HydrophobicContact CB-CD1 4.5Å; C202-V333 PolarHBondContact N-O 2.98Å; C202-V334 HydrophobicContact CB-CB 4.42Å; C202-V334 HydrophobicContact CB-CG1 4.41Å; C202-V334 HydrophobicContact CB-CG2 3.94Å; C202-V334 CarbonylContact O-C 3.46Å; C202-V334 WeakPolarHBondContact O-CA 3.41Å; C202-V335 PolarHBondContact O-N 3.12Å
203R98.8Very high96.2Very high0 Ų034.8 Ų34.80%020%0.197CC..EExtended strand (participates in β ladder)trans-124.6149.1176.665.7179.5-68.3170.6-4.1112.2Y160 P188 V189 S191 V335 G340 T344 E372Y160-R203 PolarHBondContact OH-O 3.05Å; P188-R203 WeakPolarHBondContact CA-O 3.46Å; V189-R203 HydrophobicContact CG2-CG 3.84Å; V189-R203 PolarHBondContact N-O 3.36Å; V189-R203 PolarHBondContact O-N 2.96Å; S191-R203 WeakPolarHBondContact OG-CD 3.3Å; S191-R203 VanDerWaalsContact OG-CG 3.28Å; S191-R203 WeakPolarHBondContact OG-CG 3.33Å; R203-V335 WeakPolarHBondContact CA-O 3.45Å; R203-G340 PolarHBondContact NH2-O 2.89Å; R203-T344 HydrophobicContact CB-CG2 3.76Å; R203-E372 WeakPolarHBondContact CD-OE2 3.2Å; R203-E372 IonicContact CZ-OE2 3.83Å; R203-E372 IonicContact NE-OE2 2.94Å; R203-E372 PolarHBondContact NH1-O 3.21Å; R203-E372 IonicContact NH1-OE2 3.98Å; R203-E372 PolarHBondContact NH1-OE2 3.34Å
204C98.7Very high96Very high0 Ų040.5 Ų40.50%022%0.218CC..EExtended strand (participates in β ladder)trans-159.2-177.6172.152.20000113.1Y160 R186 P188 V334 V335 H336 G340Y160-C204 WeakPolarHBondContact OH-CA 3.32Å; R186-C204 WeakPolarHBondContact O-CA 3.44Å; R186-C204 VanDerWaalsContact O-CB 3.28Å; R186-C204 WeakPolarHBondContact O-CB 3.49Å; P188-C204 HydrophobicContact CB-CB 4.4Å; P188-C204 HydrophobicContact CG-CB 4.03Å; C204-V334 WeakPolarHBondContact SG-CG1 3.21Å; C204-V335 PolarHBondContact N-O 3.41Å; C204-H336 WeakPolarHBondContact O-CA 3.44Å; C204-H336 WeakPolarHBondContact O-CB 3.27Å; C204-G340 WeakPolarHBondContact O-CA 3.49Å
205S98.5Very high96Very high0 Ų040.4 Ų40.40%022%0.219CC..PPolyproline II helixtrans-94.1171.9160.7690000111.8R182 S183 R186 D339R182-S205 WeakPolarHBondContact CD-O 3.29Å; R182-S205 PolarHBondContact NH1-O 2.62Å; S183-S205 PolarHBondContact N-OG 3.05Å; S183-S205 WeakPolarHBondContact O-CB 3.31Å; S183-S205 PolarHBondContact O-OG 2.81Å; R186-S205 PolarHBondContact O-N 3.35Å; R186-S205 PolarHBondContact O-OG 3.17Å; S205-D339 WeakPolarHBondContact CB-O 3.4Å
206Q98Very high96.1Very high0 Ų041.1 Ų41.10%021%0.213CC..PPolyproline II helixtrans-61.8153.5174.975.9-170.5-61.400112.4S183 K254 G255 C337 S338S183-Q206 PolarHBondContact N-O 3.3Å; Q206-K254 HydrophobicContact CG-CB 4.21Å; Q206-K254 HydrophobicContact CG-CD 4.45Å; Q206-K254 VanDerWaalsContact NE2-CD 3.34Å; Q206-K254 VanDerWaalsContact OE1-CB 3.25Å; Q206-G255 WeakPolarHBondContact CB-O 3.3Å; Q206-G255 PolarHBondContact OE1-O 3.2Å; Q206-C337 WeakPolarHBondContact CB-O 3.5Å; Q206-S338 WeakPolarHBondContact CB-O 3.46Å; Q206-S338 WeakPolarHBondContact CG-O 3.5Å; Q206-S338 PolarHBondContact N-O 3.49Å; Q206-S338 VanDerWaalsContact NE2-CA 3.35Å; Q206-S338 PolarHBondContact NE2-O 2.82Å; Q206-S338 VanDerWaalsContact NE2-O 3.14Å
207P97.6Very high96.3Very high0 Ų039.1 Ų39.10%021%0.206CC..BIsolated β-bridgetrans-73.7156.9170.331.9-35.5000112.5F181 A209 K254 G255 E257F181-P207 HydrophobicContact CD1-CB 3.89Å; F181-P207 HydrophobicContact CE1-CB 3.44Å; F181-P207 VanDerWaalsContact CE1-CB 3.44Å; F181-P207 HydrophobicContact CZ-CB 4.09Å; F181-P207 CarbonylContact O-C 3.54Å; F181-P207 WeakPolarHBondContact O-CA 3.45Å; P207-A209 HydrophobicContact CB-CB 4.35Å; P207-A209 HydrophobicContact CG-CB 4.31Å; P207-A209 PolarHBondContact O-N 3.33Å; P207-K254 CarbonylContact O-C 3.47Å; P207-G255 PolarHBondContact O-N 3.35Å; P207-E257 WeakPolarHBondContact CD-OE2 3.23Å; P207-E257 HydrophobicContact CG-CG 4.2Å
208L96.8Very high96.4Very high65 Ų6538.2 Ų38.234%0.3420%0.201SC..  trans-8946.1171.6-58.3-179.7000110.6F181 G210 G253 K254F181-L208 HydrophobicContact CD2-CB 4.35Å; F181-L208 WeakPolarHBondContact CE2-O 3.48Å; F181-L208 WeakPolarHBondContact O-CB 3.46Å; F181-L208 WeakPolarHBondContact O-CG 3.34Å; F181-L208 PolarHBondContact O-N 3.33Å; L208-G210 VanDerWaalsContact C-N 3.34Å; L208-G210 PolarHBondContact O-N 2.65Å; L208-G253 CarbonylContact C-O 3.56Å; L208-K254 HydrophobicContact CD2-CB 4.46Å; L208-K254 HydrophobicContact CD2-CG 3.94Å
209A93.6Very high96.5Very high12 Ų1235.2 Ų35.210%0.09919%0.187CC..  trans-73.1-23.1-172.400000113.6F181 P207 F211 S212 A213F181-A209 HydrophobicContact CZ-CB 3.91Å; P207-A209 HydrophobicContact CB-CB 4.35Å; P207-A209 HydrophobicContact CG-CB 4.31Å; P207-A209 PolarHBondContact O-N 3.33Å; A209-F211 PolarHBondContact O-N 3.27Å; A209-S212 PolarHBondContact O-N 2.87Å; A209-A213 WeakPolarHBondContact O-CA 3.25Å; A209-A213 WeakPolarHBondContact O-CB 3.31Å; A209-A213 PolarHBondContact O-N 3.5Å
210G92.4Very high96.5Very high9 Ų936.2 Ų36.29%0.09319%0.194CC..THydrogen-bonded Turntrans46.5-137.3-170.300000111.5L208 K250 G253 K254L208-G210 VanDerWaalsContact C-N 3.34Å; L208-G210 PolarHBondContact O-N 2.65Å; G210-K250 WeakPolarHBondContact O-CE 3.32Å; G210-K250 WeakPolarHBondContact O-CG 3.47Å; G210-G253 PolarHBondContact N-O 3.25Å; G210-K254 WeakPolarHBondContact CA-O 3.03Å; G210-K254 PolarHBondContact N-O 2.54Å
211F89.7Confident96.5Very high154 Ų15436.2 Ų36.268%0.67519%0.194SC*.THydrogen-bonded Turntrans-74-34.8177.3-67.3-73.4000113.9A209 A251A209-F211 PolarHBondContact O-N 3.27Å; F211-A251 HydrophobicContact CZ-CB 4.24Å
212S90.2Very high96.4Very high104 Ų10436.4 Ų36.473%0.72720%0.195SC*.THydrogen-bonded Turntrans-157.73.4-168.858.30000115.9A209 R214A209-S212 PolarHBondContact O-N 2.87Å; S212-R214 PolarHBondContact O-N 2.9Å
213A93.3Very high96.3Very high51 Ų5140.2 Ų40.242%0.42121%0.209SC..  trans-62.9137.2178.900000110.5F181 A209F181-A213 HydrophobicContact CE2-CB 4.26Å; A209-A213 WeakPolarHBondContact O-CA 3.25Å; A209-A213 WeakPolarHBondContact O-CB 3.31Å; A209-A213 PolarHBondContact O-N 3.5Å
214R94.6Very high96.3Very high135 Ų13541.8 Ų41.851%0.50922%0.216SC..  trans-119.5152.8179-67.8-17261.9-179.5-1.2110S212 E219 N261S212-R214 PolarHBondContact O-N 2.9Å; R214-E219 IonicContact CZ-OE1 2.78Å; R214-E219 IonicContact CZ-OE2 2.94Å; R214-E219 IonicContact NE-OE1 3.95Å; R214-E219 PolarHBondContact NE-OE1 3.29Å; R214-E219 VanDerWaalsContact NH2-CD 3.27Å; R214-E219 IonicContact NH2-OE1 2.81Å; R214-E219 PolarHBondContact NH2-OE1 3.48Å; R214-E219 IonicContact NH2-OE2 3.97Å; R214-E219 PolarHBondContact NH2-OE2 2.79Å; R214-N261 PolarHBondContact NE-OD1 3Å; R214-N261 PolarHBondContact NH1-OD1 3.11Å
215C97.1Very high96.3Very high10 Ų1041.9 Ų41.97%0.06822%0.217CC..  trans-135.7108.1172.2177.20000108.3F181 E217 D218 E219F181-C215 HydrophobicContact CB-CB 3.72Å; F181-C215 HydrophobicContact CD1-CB 3.45Å; F181-C215 VanDerWaalsContact CD1-CB 3.45Å; F181-C215 HydrophobicContact CD2-CB 3.65Å; F181-C215 HydrophobicContact CE1-CB 3.86Å; F181-C215 HydrophobicContact CE2-CB 4.06Å; F181-C215 HydrophobicContact CG-CB 3.31Å; F181-C215 HydrophobicContact CZ-CB 4.14Å; C215-E217 PolarHBondContact O-N 2.91Å; C215-E217 PolarHBondContact SG-OE2 3.46Å; C215-D218 HydrophobicContact CB-CB 3.84Å; C215-D218 PolarHBondContact O-N 3.19Å; C215-D218 PolarHBondContact SG-N 3.01Å; C215-E219 VanDerWaalsContact O-CG 3.31Å; C215-E219 WeakPolarHBondContact O-CG 3.46Å; C215-E219 PolarHBondContact O-N 3.24Å
216I97.6Very high96.2Very high116 Ų11643.4 Ų43.460%0.59523%0.229SC*.Hα-helixtrans-63.8-33-177.2-62.6171.1000109.8S220I216-S220 WeakPolarHBondContact O-CB 3.37Å; I216-S220 PolarHBondContact O-N 2.8Å
217E98.5Very high96.1Very high79 Ų7950.6 Ų50.637%0.36926%0.26SS..Hα-helixtrans-66.4-46.1175.7-61.677-163.700111.5V174 C215 S220 L221V174-E217 HydrophobicContact CG1-CB 4.49Å; V174-E217 VanDerWaalsContact CG1-O 3.24Å; V174-E217 WeakPolarHBondContact CG1-O 3.27Å; C215-E217 PolarHBondContact O-N 2.91Å; C215-E217 PolarHBondContact SG-OE2 3.46Å; E217-S220 CarbonylContact O-C 3.57Å; E217-S220 WeakPolarHBondContact O-CA 3.36Å; E217-S220 WeakPolarHBondContact O-CB 3.38Å; E217-S220 PolarHBondContact O-N 2.99Å; E217-S220 VanDerWaalsContact O-N 3.15Å; E217-L221 PolarHBondContact O-N 2.69Å
218D98.3Very high96.1Very high0 Ų050.9 Ų50.90%026%0.262CS..Hα-helixtrans-64.8-44.2177.3-166.584.9000112S178 F181 R182 C215 S220 L221 M222 Y262S178-D218 PolarHBondContact OG-OD1 3.43Å; F181-D218 HydrophobicContact CD1-CB 3.79Å; F181-D218 HydrophobicContact CE1-CB 4.49Å; R182-D218 IonicContact CZ-OD1 3.97Å; R182-D218 IonicContact CZ-OD2 3.54Å; R182-D218 IonicContact NE-OD1 3.24Å; R182-D218 PolarHBondContact NE-OD1 3.33Å; R182-D218 IonicContact NE-OD2 3.8Å; R182-D218 IonicContact NH2-OD1 2.87Å; R182-D218 PolarHBondContact NH2-OD1 3.16Å; R182-D218 IonicContact NH2-OD2 2.82Å; R182-D218 PolarHBondContact NH2-OD2 2.93Å; C215-D218 HydrophobicContact CB-CB 3.84Å; C215-D218 PolarHBondContact O-N 3.19Å; C215-D218 PolarHBondContact SG-N 3.01Å; D218-S220 PolarHBondContact O-N 3.02Å; D218-L221 PolarHBondContact O-N 2.83Å; D218-M222 WeakPolarHBondContact O-CG 3.43Å; D218-M222 PolarHBondContact O-N 2.96Å; D218-Y262 PolarHBondContact OD2-OH 3.3Å
219E97.9Very high96.1Very high5 Ų547.8 Ų47.82%0.02325%0.246CC..Hα-helixtrans-58.9-38.4172.2-64.9167.9-163.900111.5R214 C215 R223 Y262R214-E219 IonicContact CZ-OE1 2.78Å; R214-E219 IonicContact CZ-OE2 2.94Å; R214-E219 IonicContact NE-OE1 3.95Å; R214-E219 PolarHBondContact NE-OE1 3.29Å; R214-E219 VanDerWaalsContact NH2-CD 3.27Å; R214-E219 IonicContact NH2-OE1 2.81Å; R214-E219 PolarHBondContact NH2-OE1 3.48Å; R214-E219 IonicContact NH2-OE2 3.97Å; R214-E219 PolarHBondContact NH2-OE2 2.79Å; C215-E219 VanDerWaalsContact O-CG 3.31Å; C215-E219 WeakPolarHBondContact O-CG 3.46Å; C215-E219 PolarHBondContact O-N 3.24Å; E219-R223 WeakPolarHBondContact O-CG 3.43Å; E219-R223 PolarHBondContact O-N 3.3Å; E219-R223 VanDerWaalsContact O-N 3.17Å; E219-R223 IonicContact OE2-NH2 2.73Å; E219-R223 PolarHBondContact OE2-NH2 2.82Å; E219-Y262 HydrophobicContact CB-CD1 4.41Å; E219-Y262 HydrophobicContact CB-CE1 4.29Å; E219-Y262 HydrophobicContact CG-CD1 4.14Å; E219-Y262 HydrophobicContact CG-CD2 4.47Å; E219-Y262 HydrophobicContact CG-CE1 3.86Å; E219-Y262 HydrophobicContact CG-CE2 4.2Å; E219-Y262 HydrophobicContact CG-CG 4.45Å
220S97.9Very high96.1Very high21 Ų2151.5 Ų51.515%0.14727%0.269CS..Hα-helixtrans-67.2-42.4175.9-172.50000112.2I216 E217 D218 M222 R223 H224I216-S220 WeakPolarHBondContact O-CB 3.37Å; I216-S220 PolarHBondContact O-N 2.8Å; E217-S220 CarbonylContact O-C 3.57Å; E217-S220 WeakPolarHBondContact O-CA 3.36Å; E217-S220 WeakPolarHBondContact O-CB 3.38Å; E217-S220 PolarHBondContact O-N 2.99Å; E217-S220 VanDerWaalsContact O-N 3.15Å; D218-S220 PolarHBondContact O-N 3.02Å; S220-M222 VanDerWaalsContact C-N 3.32Å; S220-M222 PolarHBondContact O-N 2.85Å; S220-R223 VanDerWaalsContact CA-NH1 3.31Å; S220-R223 WeakPolarHBondContact O-CB 3.27Å; S220-R223 PolarHBondContact O-N 3.44Å; S220-R223 VanDerWaalsContact O-N 3.16Å; S220-H224 PolarHBondContact O-N 2.9Å; S220-H224 PolarHBondContact O-ND1 3.29Å; S220-H224 PolarHBondContact OG-CE1 3.49Å
221L98.5Very high96.1Very high0 Ų057.6 Ų57.60%030%0.295CS..Hα-helixtrans-60-43.6175.8177.457.7000111V170 V174 L175 S178 L187 P188 E217 D218 R223 H224 I225V170-L221 HydrophobicContact CG2-CD1 3.98Å; V174-L221 HydrophobicContact CG1-CB 4.06Å; L175-L221 HydrophobicContact CD2-CD1 3.94Å; L175-L221 HydrophobicContact CD2-CD2 4.35Å; S178-L221 WeakPolarHBondContact OG-CD2 3.42Å; L187-L221 HydrophobicContact CD1-CD2 4.42Å; P188-L221 HydrophobicContact CB-CD2 3.95Å; P188-L221 HydrophobicContact CB-CG 4.38Å; P188-L221 HydrophobicContact CG-CD2 3.96Å; E217-L221 PolarHBondContact O-N 2.69Å; D218-L221 PolarHBondContact O-N 2.83Å; L221-R223 VanDerWaalsContact C-N 3.31Å; L221-R223 PolarHBondContact O-N 2.9Å; L221-H224 WeakPolarHBondContact O-CB 3.08Å; L221-H224 PolarHBondContact O-N 3.34Å; L221-I225 HydrophobicContact CD1-CD1 4.46Å; L221-I225 HydrophobicContact CD1-CG1 4.47Å; L221-I225 HydrophobicContact CG-CD1 4.29Å; L221-I225 WeakPolarHBondContact O-CG1 3.41Å; L221-I225 PolarHBondContact O-N 2.61Å
222M97.9Very high96.4Very high4 Ų451.5 Ų51.52%0.0227%0.272CS..Hα-helixtrans-59.3-40.9175-67.5-58.8-178.300112.4P188 D218 S220 H224 I225 A226 L235 I237 Y262 V334P188-M222 HydrophobicContact CB-CE 4.38Å; P188-M222 HydrophobicContact CG-CE 3.49Å; P188-M222 VanDerWaalsContact CG-CE 3.49Å; P188-M222 HydrophobicContact CG-SD 4.24Å; D218-M222 WeakPolarHBondContact O-CG 3.43Å; D218-M222 PolarHBondContact O-N 2.96Å; S220-M222 VanDerWaalsContact C-N 3.32Å; S220-M222 PolarHBondContact O-N 2.85Å; M222-H224 VanDerWaalsContact C-N 3.33Å; M222-H224 PolarHBondContact O-N 2.88Å; M222-I225 PolarHBondContact O-N 3.39Å; M222-I225 HydrophobicContact SD-CD1 4.33Å; M222-A226 PolarHBondContact O-N 2.9Å; M222-L235 HydrophobicContact CB-CD2 4.26Å; M222-L235 HydrophobicContact SD-CD2 4.17Å; M222-I237 HydrophobicContact CE-CD1 4.29Å; M222-I237 HydrophobicContact SD-CD1 4.48Å; M222-Y262 HydrophobicContact CB-CD1 4.04Å; M222-Y262 HydrophobicContact CB-CE1 4.44Å; M222-Y262 HydrophobicContact CG-CD1 3.75Å; M222-Y262 HydrophobicContact CG-CE1 3.76Å; M222-V334 HydrophobicContact CE-CG1 4.08Å; M222-V334 HydrophobicContact SD-CG1 4.42Å; M222-V334 HydrophobicContact SD-CG2 3.9Å
223R97.1Very high96.4Very high79 Ų7955.5 Ų55.530%0.29828%0.276SS..Hα-helixtrans-63.8-37.4173.9-67.9179.7-134.8111.72.8112.2E219 S220 L221 A226 K227E219-R223 WeakPolarHBondContact O-CG 3.43Å; E219-R223 PolarHBondContact O-N 3.3Å; E219-R223 VanDerWaalsContact O-N 3.17Å; E219-R223 IonicContact OE2-NH2 2.73Å; E219-R223 PolarHBondContact OE2-NH2 2.82Å; S220-R223 VanDerWaalsContact CA-NH1 3.31Å; S220-R223 WeakPolarHBondContact O-CB 3.27Å; S220-R223 PolarHBondContact O-N 3.44Å; S220-R223 VanDerWaalsContact O-N 3.16Å; L221-R223 VanDerWaalsContact C-N 3.31Å; L221-R223 PolarHBondContact O-N 2.9Å; R223-A226 PolarHBondContact O-N 2.64Å; R223-K227 VanDerWaalsContact O-CG 3.27Å; R223-K227 WeakPolarHBondContact O-CG 3.28Å; R223-K227 PolarHBondContact O-N 3.39Å
224H98.1Very high96.6Very high34 Ų3455 Ų5516%0.15727%0.268CS..Hα-helixtrans-66.9-40175.5-73.684.4000111.6P167 V170 S220 L221 M222 K227 T228P167-H224 HydrophobicContact CB-CB 3.95Å; P167-H224 HydrophobicContact CG-CB 4.02Å; V170-H224 HydrophobicContact CB-CB 4.41Å; V170-H224 HydrophobicContact CG2-CB 4.46Å; S220-H224 PolarHBondContact O-N 2.9Å; S220-H224 PolarHBondContact O-ND1 3.29Å; S220-H224 PolarHBondContact OG-CE1 3.49Å; L221-H224 WeakPolarHBondContact O-CB 3.08Å; L221-H224 PolarHBondContact O-N 3.34Å; M222-H224 VanDerWaalsContact C-N 3.33Å; M222-H224 PolarHBondContact O-N 2.88Å; H224-K227 PolarHBondContact O-N 3.4Å; H224-T228 WeakPolarHBondContact O-CG2 3.34Å; H224-T228 PolarHBondContact O-N 3.03Å
225I98.3Very high96.7Very high1 Ų148.7 Ų48.71%0.00525%0.245CC..Hα-helixtrans-60.9-49.2173.4-67.8170.2000110.1W145 P167 P188 V200 C202 L221 M222 K227 T228 L235 V334W145-I225 HydrophobicContact CH2-CG1 4.3Å; W145-I225 HydrophobicContact CH2-CG2 4.44Å; P167-I225 HydrophobicContact CG-CG1 3.76Å; P188-I225 HydrophobicContact CB-CD1 3.52Å; V200-I225 HydrophobicContact CG2-CG2 4.38Å; C202-I225 HydrophobicContact CB-CD1 4.5Å; L221-I225 HydrophobicContact CD1-CD1 4.46Å; L221-I225 HydrophobicContact CD1-CG1 4.47Å; L221-I225 HydrophobicContact CG-CD1 4.29Å; L221-I225 WeakPolarHBondContact O-CG1 3.41Å; L221-I225 PolarHBondContact O-N 2.61Å; M222-I225 PolarHBondContact O-N 3.39Å; M222-I225 HydrophobicContact SD-CD1 4.33Å; I225-K227 VanDerWaalsContact C-N 3.26Å; I225-K227 PolarHBondContact O-N 2.73Å; I225-T228 WeakPolarHBondContact O-CB 3.28Å; I225-T228 PolarHBondContact O-N 3.45Å; I225-T228 PolarHBondContact O-OG1 3.07Å; I225-L235 HydrophobicContact CG2-CD1 3.98Å; I225-L235 HydrophobicContact CG2-CD2 4.42Å; I225-V334 HydrophobicContact CD1-CG2 4.32Å; I225-V334 HydrophobicContact CG2-CG2 4.27Å
226A97.2Very high96.8Very high32 Ų3250.2 Ų50.226%0.26425%0.25SC..Hα-helixtrans-56-40.6177.500000112.1M222 R223 T228 N229 L235M222-A226 PolarHBondContact O-N 2.9Å; R223-A226 PolarHBondContact O-N 2.64Å; A226-T228 PolarHBondContact O-N 3.48Å; A226-N229 CarbonylContact O-C 3.27Å; A226-N229 PolarHBondContact O-N 3.06Å; A226-N229 VanDerWaalsContact O-N 3.11Å; A226-L235 HydrophobicContact CB-CB 4.17Å; A226-L235 HydrophobicContact CB-CD2 4.5Å
227K96.7Very high96.8Very high151 Ų15144.7 Ų44.766%0.65722%0.222SC*.Hα-helixtrans-65.6-18177.7-75174.2-179.8-175.20114.7R223 H224 I225 N229R223-K227 VanDerWaalsContact O-CG 3.27Å; R223-K227 WeakPolarHBondContact O-CG 3.28Å; R223-K227 PolarHBondContact O-N 3.39Å; H224-K227 PolarHBondContact O-N 3.4Å; I225-K227 VanDerWaalsContact C-N 3.26Å; I225-K227 PolarHBondContact O-N 2.73Å; K227-N229 PolarHBondContact O-N 2.9Å
228T97.5Very high96.9Very high6 Ų640.9 Ų40.94%0.03720%0.204CC..THydrogen-bonded Turntrans-70.8-17.1174.168.90000112.5K144 W145 P167 H224 I225 A226 P230K144-T228 HydrophobicContact CB-CG2 4.36Å; K144-T228 WeakPolarHBondContact CD-O 3.1Å; K144-T228 PolarHBondContact NZ-O 3.13Å; W145-T228 HydrophobicContact CD2-CG2 4.37Å; W145-T228 HydrophobicContact CH2-CG2 4.35Å; W145-T228 HydrophobicContact CZ2-CG2 3.68Å; W145-T228 VanDerWaalsContact CZ2-OG1 3.26Å; W145-T228 WeakPolarHBondContact CZ2-OG1 2.89Å; P167-T228 HydrophobicContact CB-CG2 3.87Å; P167-T228 HydrophobicContact CG-CG2 4.09Å; H224-T228 WeakPolarHBondContact O-CG2 3.34Å; H224-T228 PolarHBondContact O-N 3.03Å; I225-T228 WeakPolarHBondContact O-CB 3.28Å; I225-T228 PolarHBondContact O-N 3.45Å; I225-T228 PolarHBondContact O-OG1 3.07Å; A226-T228 PolarHBondContact O-N 3.48Å; T228-P230 WeakPolarHBondContact O-CD 3.38Å
229N96.8Very high96.9Very high1 Ų140.9 Ų40.91%0.00520%0.204CC..  trans-122.979.8173.5178.63.1000109.5A226 K227 Q231 S232 G330 S332A226-N229 CarbonylContact O-C 3.27Å; A226-N229 PolarHBondContact O-N 3.06Å; A226-N229 VanDerWaalsContact O-N 3.11Å; K227-N229 PolarHBondContact O-N 2.9Å; N229-Q231 PolarHBondContact O-N 3.39Å; N229-Q231 VanDerWaalsContact O-N 3.16Å; N229-Q231 PolarHBondContact OD1-N 2.85Å; N229-S232 PolarHBondContact O-N 3.29Å; N229-S232 VanDerWaalsContact O-N 3.15Å; N229-S232 PolarHBondContact OD1-N 2.62Å; N229-G330 PolarHBondContact ND2-O 3.36Å; N229-S332 VanDerWaalsContact CB-OG 3.27Å; N229-S332 WeakPolarHBondContact CB-OG 3.27Å; N229-S332 PolarHBondContact ND2-OG 3.05Å; N229-S332 VanDerWaalsContact ND2-OG 3.16Å
230P92.9Very high96.9Very high90 Ų9040.7 Ų40.758%0.58420%0.203SC*.THydrogen-bonded Turntrans-67.1-13.9-176.828.9-35.5000113.5K144 T228 S232K144-P230 VanDerWaalsContact NZ-CD 3.34Å; T228-P230 WeakPolarHBondContact O-CD 3.38Å; P230-S232 VanDerWaalsContact C-N 3.33Å
231Q92.2Very high96.9Very high136 Ų13639.7 Ų39.764%0.63620%0.196SC*.THydrogen-bonded Turntrans-75.7-25.5177-54.9-175.921.900111.6N229N229-Q231 PolarHBondContact O-N 3.39Å; N229-Q231 VanDerWaalsContact O-N 3.16Å; N229-Q231 PolarHBondContact OD1-N 2.85Å
232S95Very high96.8Very high27 Ų2740.3 Ų40.319%0.18920%0.2CC..  trans-89.4133.5175.5-170.60000112.2N229 P230 T234 G330N229-S232 PolarHBondContact O-N 3.29Å; N229-S232 VanDerWaalsContact O-N 3.15Å; N229-S232 PolarHBondContact OD1-N 2.62Å; P230-S232 VanDerWaalsContact C-N 3.33Å; S232-T234 VanDerWaalsContact C-N 3.29Å; S232-T234 PolarHBondContact OG-N 2.82Å; S232-T234 VanDerWaalsContact OG-N 3.15Å; S232-T234 PolarHBondContact OG-O 3.28Å; S232-G330 WeakPolarHBondContact CB-O 3.5Å
233K91.6Very high96.7Very high187 Ų18745.9 Ų45.981%0.81322%0.224SC*.SBendtrans-81.9-9.1170.8-64.1-178.6-178.3176.80112.9
234T96.6Very high96.6Very high42 Ų4247.8 Ų47.826%0.25824%0.239SC..  trans-143.9142-169.7-57.70000111.2S232 F236 N264 R266S232-T234 VanDerWaalsContact C-N 3.29Å; S232-T234 PolarHBondContact OG-N 2.82Å; S232-T234 VanDerWaalsContact OG-N 3.15Å; S232-T234 PolarHBondContact OG-O 3.28Å; T234-F236 HydrophobicContact CG2-CD1 3.92Å; T234-F236 HydrophobicContact CG2-CE1 3.83Å; T234-N264 CarbonylContact C-O 3.48Å; T234-N264 VanDerWaalsContact CA-O 3.29Å; T234-N264 WeakPolarHBondContact CA-O 3.28Å; T234-R266 HydrophobicContact CG2-CB 4.05Å; T234-R266 HydrophobicContact CG2-CG 3.54Å
235L98Very high96.4Very high2 Ų248 Ų481%0.0124%0.241CC..EExtended strand (participates in β ladder)trans-104.2130.9169.6178.572.4000108.8M222 I225 A226 N264 V265 R266 S332 V334M222-L235 HydrophobicContact CB-CD2 4.26Å; M222-L235 HydrophobicContact SD-CD2 4.17Å; I225-L235 HydrophobicContact CG2-CD1 3.98Å; I225-L235 HydrophobicContact CG2-CD2 4.42Å; A226-L235 HydrophobicContact CB-CB 4.17Å; A226-L235 HydrophobicContact CB-CD2 4.5Å; L235-N264 PolarHBondContact N-O 2.79Å; L235-V265 HydrophobicContact CB-CG2 4.17Å; L235-V265 HydrophobicContact CD2-CG2 4.22Å; L235-V265 CarbonylContact O-C 3.54Å; L235-V265 VanDerWaalsContact O-CA 3.24Å; L235-V265 WeakPolarHBondContact O-CA 3.3Å; L235-R266 PolarHBondContact O-N 3.16Å; L235-S332 WeakPolarHBondContact CD1-O 3.45Å; L235-V334 HydrophobicContact CD1-CG2 4.17Å; L235-V334 HydrophobicContact CD2-CG2 4.04Å; L235-V334 HydrophobicContact CG-CG2 4.37Å
236F98.5Very high96.2Very high41 Ų4147.9 Ų47.918%0.1824%0.241CC..EExtended strand (participates in β ladder)trans-90.5133.8173.2-72.40.4000110.3T234 R266 H268 F322 A326 T331 S332 V333 V334T234-F236 HydrophobicContact CG2-CD1 3.92Å; T234-F236 HydrophobicContact CG2-CE1 3.83Å; F236-R266 CarbonylContact C-O 3.53Å; F236-R266 WeakPolarHBondContact CA-O 3.19Å; F236-R266 HydrophobicContact CD1-CB 3.75Å; F236-R266 HydrophobicContact CD1-CG 4.49Å; F236-R266 HydrophobicContact CE1-CB 3.85Å; F236-R266 HydrophobicContact CE1-CG 4.2Å; F236-H268 AromaticContact CD2-NE2 3.95Å; F236-H268 AromaticContact CE2-NE2 3.97Å; F236-F322 HydrophobicContact CD2-CE1 4.1Å; F236-F322 AromaticContact CD2-CZ 3.87Å; F236-F322 HydrophobicContact CD2-CZ 3.87Å; F236-F322 AromaticContact CE2-CZ 3.98Å; F236-F322 HydrophobicContact CE2-CZ 3.98Å; F236-A326 HydrophobicContact CD2-CB 3.83Å; F236-A326 HydrophobicContact CE2-CB 4.06Å; F236-T331 HydrophobicContact CB-CG2 4.3Å; F236-T331 HydrophobicContact CD1-CG2 3.68Å; F236-T331 HydrophobicContact CD2-CG2 3.81Å; F236-T331 HydrophobicContact CE1-CG2 3.89Å; F236-T331 HydrophobicContact CE2-CG2 4Å; F236-T331 HydrophobicContact CG-CG2 3.65Å; F236-T331 HydrophobicContact CZ-CG2 4.04Å; F236-S332 PolarHBondContact N-O 3.21Å; F236-V333 HydrophobicContact CB-CG1 4.41Å; F236-V333 HydrophobicContact CB-CG2 4.25Å; F236-V333 CarbonylContact O-C 3.57Å; F236-V333 VanDerWaalsContact O-CA 3.31Å; F236-V333 WeakPolarHBondContact O-CA 3.38Å; F236-V334 PolarHBondContact O-N 3.21Å
237I98.4Very high96.1Very high0 Ų051 Ų510%025%0.251CS..EExtended strand (participates in β ladder)trans-106120.8165.2-60.7-179.4000107.8M222 E257 V265 R266 Y267 H268 V334M222-I237 HydrophobicContact CE-CD1 4.29Å; M222-I237 HydrophobicContact SD-CD1 4.48Å; I237-E257 HydrophobicContact CD1-CB 4.11Å; I237-E257 HydrophobicContact CD1-CG 3.86Å; I237-V265 HydrophobicContact CB-CG1 4.25Å; I237-V265 HydrophobicContact CD1-CG1 3.55Å; I237-V265 HydrophobicContact CD1-CG2 4.46Å; I237-V265 HydrophobicContact CG1-CG1 3.6Å; I237-R266 PolarHBondContact N-O 2.83Å; I237-Y267 HydrophobicContact CB-CD2 3.69Å; I237-Y267 HydrophobicContact CB-CE2 3.86Å; I237-Y267 HydrophobicContact CD1-CD2 4.49Å; I237-Y267 HydrophobicContact CG2-CD2 3.75Å; I237-Y267 HydrophobicContact CG2-CE2 3.34Å; I237-Y267 WeakPolarHBondContact O-CA 3.31Å; I237-H268 PolarHBondContact O-N 3.4Å; I237-V334 CarbonylContact C-O 3.36Å; I237-V334 WeakPolarHBondContact CA-O 3.38Å; I237-V334 HydrophobicContact CG1-CB 4.4Å
238V98.6Very high96Very high0 Ų048.1 Ų48.10%025%0.246CC..EExtended strand (participates in β ladder)trans-106.6108.6179.7172.50000108.9T240 H268 F270 T319 F322 I323 V333 V334 V335 H336V238-T240 HydrophobicContact CG1-CG2 4.48Å; V238-H268 WeakPolarHBondContact CA-O 3.24Å; V238-H268 HydrophobicContact CG2-CB 4.38Å; V238-F270 HydrophobicContact CG1-CD2 3.7Å; V238-F270 HydrophobicContact CG1-CE2 3.83Å; V238-F270 HydrophobicContact CG2-CE2 4.38Å; V238-T319 HydrophobicContact CG1-CG2 4.07Å; V238-F322 HydrophobicContact CG2-CD1 4.09Å; V238-F322 HydrophobicContact CG2-CE1 3.78Å; V238-I323 HydrophobicContact CG1-CD1 4.24Å; V238-I323 HydrophobicContact CG1-CG1 4.29Å; V238-I323 HydrophobicContact CG2-CG1 4.25Å; V238-V333 HydrophobicContact CB-CG1 4.09Å; V238-V333 HydrophobicContact CG2-CG1 3.53Å; V238-V334 PolarHBondContact N-O 3.29Å; V238-V335 HydrophobicContact CB-CG2 4.32Å; V238-V335 HydrophobicContact CG1-CG1 4.37Å; V238-V335 WeakPolarHBondContact O-CA 3.35Å; V238-H336 PolarHBondContact O-N 3.32Å
239D98.4Very high95.9Very high0 Ų049.3 Ų49.30%025%0.252CS..EExtended strand (participates in β ladder)trans-92.7109169-164.3-27.3000109.2R241 Y267 H268 F269 F270 H336D239-R241 PolarHBondContact O-N 2.87Å; D239-R241 VanDerWaalsContact O-N 3.09Å; D239-R241 VanDerWaalsContact OD1-CB 3.25Å; D239-R241 WeakPolarHBondContact OD1-CB 3.43Å; D239-R241 WeakPolarHBondContact OD1-CG 3.23Å; D239-R241 IonicContact OD1-CZ 3.96Å; D239-R241 PolarHBondContact OD1-N 3.07Å; D239-R241 IonicContact OD1-NE 2.88Å; D239-R241 PolarHBondContact OD1-NE 2.87Å; D239-R241 IonicContact OD1-NH2 3.61Å; D239-R241 IonicContact OD2-CZ 3.29Å; D239-R241 IonicContact OD2-NE 2.65Å; D239-R241 PolarHBondContact OD2-NE 3.35Å; D239-R241 IonicContact OD2-NH2 2.87Å; D239-R241 PolarHBondContact OD2-NH2 3.16Å; D239-Y267 HydrophobicContact CB-CE1 3.5Å; D239-Y267 VanDerWaalsContact CB-CE1 3.5Å; D239-Y267 VanDerWaalsContact CB-OH 3.24Å; D239-Y267 WeakPolarHBondContact CB-OH 3.49Å; D239-Y267 PolarHBondContact OD2-OH 2.83Å; D239-H268 PolarHBondContact N-O 2.87Å; D239-F269 HydrophobicContact CB-CD1 3.74Å; D239-F269 HydrophobicContact CB-CE1 3.89Å; D239-F269 CarbonylContact O-C 3.52Å; D239-F269 WeakPolarHBondContact O-CA 3.37Å; D239-F269 WeakPolarHBondContact OD2-CE1 3.49Å; D239-F270 PolarHBondContact O-N 3.08Å; D239-H336 IonicContact OD2-CE1 3.41Å; D239-H336 PolarHBondContact OD2-CE1 3.03Å
240T98.5Very high95.7Very high0 Ų051.5 Ų51.50%026%0.261CS..  trans-66.8-10.8-178.456.70000113.3V238 F270 V272 T319 V335 H336 C337 R343 T347V238-T240 HydrophobicContact CG1-CG2 4.48Å; T240-F270 CarbonylContact C-O 3.58Å; T240-F270 CarbonylContact O-C 3.55Å; T240-F270 VanDerWaalsContact O-O 3.1Å; T240-V272 WeakPolarHBondContact O-CA 3.5Å; T240-V272 WeakPolarHBondContact O-CB 3.45Å; T240-V272 PolarHBondContact O-N 3.13Å; T240-T319 HydrophobicContact CG2-CG2 4.18Å; T240-V335 HydrophobicContact CG2-CG1 3.79Å; T240-H336 WeakPolarHBondContact CG2-O 3.4Å; T240-H336 PolarHBondContact N-O 3.13Å; T240-H336 PolarHBondContact OG1-O 3.12Å; T240-C337 WeakPolarHBondContact OG1-CA 3.35Å; T240-C337 WeakPolarHBondContact OG1-CB 3.4Å; T240-R343 WeakPolarHBondContact OG1-CB 3.17Å; T240-T347 HydrophobicContact CG2-CG2 3.99Å; T240-T347 WeakPolarHBondContact CG2-OG1 3.32Å
241R98Very high95.7Very high0 Ų050 Ų500%026%0.257CS..SBendtrans-83.1144.4-175.7-56.3177-70-177.5-6.7112.3D239 K243 N249 G255 F270 C337 S338D239-R241 PolarHBondContact O-N 2.87Å; D239-R241 VanDerWaalsContact O-N 3.09Å; D239-R241 VanDerWaalsContact OD1-CB 3.25Å; D239-R241 WeakPolarHBondContact OD1-CB 3.43Å; D239-R241 WeakPolarHBondContact OD1-CG 3.23Å; D239-R241 IonicContact OD1-CZ 3.96Å; D239-R241 PolarHBondContact OD1-N 3.07Å; D239-R241 IonicContact OD1-NE 2.88Å; D239-R241 PolarHBondContact OD1-NE 2.87Å; D239-R241 IonicContact OD1-NH2 3.61Å; D239-R241 IonicContact OD2-CZ 3.29Å; D239-R241 IonicContact OD2-NE 2.65Å; D239-R241 PolarHBondContact OD2-NE 3.35Å; D239-R241 IonicContact OD2-NH2 2.87Å; D239-R241 PolarHBondContact OD2-NH2 3.16Å; R241-K243 PolarHBondContact O-N 3.33Å; R241-N249 PolarHBondContact NH1-ND2 2.64Å; R241-G255 PolarHBondContact NH2-O 3.11Å; R241-F270 CarbonylContact C-O 3.58Å; R241-C337 HydrophobicContact CG-CB 4.45Å; R241-S338 WeakPolarHBondContact CD-OG 3.35Å
242P96.8Very high95.8Very high14 Ų1448.3 Ų48.39%0.09126%0.256CS..  trans-50.9135.5163.8-24.230.1000110.3I244 N245 A246 F270 A271 V272P242-I244 HydrophobicContact CB-CG2 4.23Å; P242-I244 PolarHBondContact O-N 3.45Å; P242-N245 WeakPolarHBondContact O-CA 3.42Å; P242-N245 WeakPolarHBondContact O-CB 3.32Å; P242-N245 PolarHBondContact O-N 3.02Å; P242-A246 PolarHBondContact O-N 2.84Å; P242-A246 VanDerWaalsContact O-N 3.11Å; P242-F270 WeakPolarHBondContact CA-O 3.48Å; P242-A271 HydrophobicContact CG-CB 4.38Å; P242-V272 VanDerWaalsContact CD-O 3.27Å; P242-V272 WeakPolarHBondContact CD-O 3.24Å
243K95.8Very high95.6Very high120 Ų12048.9 Ų48.952%0.52227%0.266SS..Hα-helixtrans-51.1-38.4-176.7-169.7178.2-175176.40112.6R241 N245 A246 M247 F269R241-K243 PolarHBondContact O-N 3.33Å; K243-N245 PolarHBondContact O-N 3.41Å; K243-A246 WeakPolarHBondContact O-CB 3.37Å; K243-A246 PolarHBondContact O-N 3.35Å; K243-M247 HydrophobicContact CD-CE 4.17Å; K243-M247 HydrophobicContact CG-CE 4.05Å; K243-M247 WeakPolarHBondContact O-CG 3.46Å; K243-M247 PolarHBondContact O-N 2.91Å; K243-F269 HydrophobicContact CB-CD1 4.37Å; K243-F269 HydrophobicContact CB-CG 4.24Å; K243-F269 HydrophobicContact CD-CD2 4.5Å; K243-F269 HydrophobicContact CG-CD2 4.25Å; K243-F269 HydrophobicContact CG-CE2 4.3Å; K243-F269 HydrophobicContact CG-CG 4.38Å; K243-F269 HydrophobicContact CG-CZ 4.46Å
244I95.3Very high95.7Very high119 Ų11942.8 Ų42.861%0.6124%0.24SC*.Hα-helixtrans-62.2-42.2177-165.4164.8000112.6P242 A246 M247 V248P242-I244 HydrophobicContact CB-CG2 4.23Å; P242-I244 PolarHBondContact O-N 3.45Å; I244-A246 VanDerWaalsContact C-N 3.32Å; I244-A246 PolarHBondContact O-N 2.93Å; I244-M247 WeakPolarHBondContact O-CB 3.38Å; I244-M247 PolarHBondContact O-N 3.39Å; I244-V248 WeakPolarHBondContact O-CG2 3.34Å; I244-V248 PolarHBondContact O-N 2.78Å
245N93.8Very high95.6Very high38 Ų3840.8 Ų40.820%0.20323%0.227CC..Hα-helixtrans-67-36.4176.9-69.9-12.7000110.8P242 K243 V248 N249P242-N245 WeakPolarHBondContact O-CA 3.42Å; P242-N245 WeakPolarHBondContact O-CB 3.32Å; P242-N245 PolarHBondContact O-N 3.02Å; K243-N245 PolarHBondContact O-N 3.41Å; N245-V248 PolarHBondContact O-N 2.88Å; N245-N249 PolarHBondContact O-N 2.73Å; N245-N249 VanDerWaalsContact O-N 3.12Å; N245-N249 PolarHBondContact O-ND2 3.49Å
246A94.3Very high95.4Very high0 Ų042.4 Ų42.40%023%0.234CC..Hα-helixtrans-65.1-38.9173.600000112P242 K243 I244 N249 K250 F256 F269P242-A246 PolarHBondContact O-N 2.84Å; P242-A246 VanDerWaalsContact O-N 3.11Å; K243-A246 WeakPolarHBondContact O-CB 3.37Å; K243-A246 PolarHBondContact O-N 3.35Å; I244-A246 VanDerWaalsContact C-N 3.32Å; I244-A246 PolarHBondContact O-N 2.93Å; A246-N249 PolarHBondContact O-N 3.15Å; A246-K250 PolarHBondContact O-N 2.9Å; A246-F256 HydrophobicContact CB-CD1 3.92Å; A246-F256 HydrophobicContact CB-CE1 4.36Å; A246-F269 HydrophobicContact CB-CD1 4.28Å; A246-F269 HydrophobicContact CB-CE1 3.51Å; A246-F269 HydrophobicContact CB-CZ 4.32Å
247M95.3Very high95.2Very high98 Ų9840.7 Ų40.748%0.48323%0.227SC..Hα-helixtrans-64.7-41.6174.1-69.7-175.4-18000112.9K243 I244 N249 K250 A251K243-M247 HydrophobicContact CD-CE 4.17Å; K243-M247 HydrophobicContact CG-CE 4.05Å; K243-M247 WeakPolarHBondContact O-CG 3.46Å; K243-M247 PolarHBondContact O-N 2.91Å; I244-M247 WeakPolarHBondContact O-CB 3.38Å; I244-M247 PolarHBondContact O-N 3.39Å; M247-N249 VanDerWaalsContact C-N 3.34Å; M247-N249 PolarHBondContact O-N 3.28Å; M247-K250 VanDerWaalsContact O-CB 3.26Å; M247-K250 WeakPolarHBondContact O-CB 3.47Å; M247-K250 PolarHBondContact O-N 3.48Å; M247-K250 VanDerWaalsContact O-N 3.13Å; M247-A251 PolarHBondContact O-N 3.01Å; M247-A251 VanDerWaalsContact O-N 3.09Å
248V94.7Very high94.9Very high89 Ų8942.6 Ų42.654%0.53924%0.237SC..Hα-helixtrans-61.4-43.8175.6172.90000110.9I244 N245 K250 A251 T252I244-V248 WeakPolarHBondContact O-CG2 3.34Å; I244-V248 PolarHBondContact O-N 2.78Å; N245-V248 PolarHBondContact O-N 2.88Å; V248-K250 VanDerWaalsContact C-N 3.27Å; V248-K250 PolarHBondContact O-N 3.24Å; V248-A251 WeakPolarHBondContact O-CB 3.44Å; V248-A251 PolarHBondContact O-N 3.17Å; V248-A251 VanDerWaalsContact O-N 3.17Å; V248-T252 PolarHBondContact O-N 3.02Å
249N93.6Very high94.5Very high31 Ų3146.4 Ų46.417%0.16626%0.255CS..Hα-helixtrans-61.9-35.5174.7-75.1-60.3000112.4R241 N245 A246 M247 A251 T252 K254R241-N249 PolarHBondContact NH1-ND2 2.64Å; N245-N249 PolarHBondContact O-N 2.73Å; N245-N249 VanDerWaalsContact O-N 3.12Å; N245-N249 PolarHBondContact O-ND2 3.49Å; A246-N249 PolarHBondContact O-N 3.15Å; M247-N249 VanDerWaalsContact C-N 3.34Å; M247-N249 PolarHBondContact O-N 3.28Å; N249-A251 VanDerWaalsContact C-N 3.32Å; N249-A251 PolarHBondContact O-N 2.63Å; N249-T252 PolarHBondContact O-N 3.35Å; N249-T252 PolarHBondContact O-OG1 3.49Å; N249-T252 VanDerWaalsContact O-OG1 3.11Å; N249-K254 HydrophobicContact CB-CB 4.22Å; N249-K254 CarbonylContact O-C 3.49Å; N249-K254 WeakPolarHBondContact O-CA 3.34Å; N249-K254 WeakPolarHBondContact O-CB 3.31Å; N249-K254 PolarHBondContact O-N 3.38Å
250K93.9Very high94.2Very high47 Ų4756 Ų5620%0.20429%0.291CS..Hα-helixtrans-60.7-41.6174.9-163.6175.7179.4166.40111.8G210 A246 M247 V248 T252 G253 K254 F256G210-K250 WeakPolarHBondContact O-CE 3.32Å; G210-K250 WeakPolarHBondContact O-CG 3.47Å; A246-K250 PolarHBondContact O-N 2.9Å; M247-K250 VanDerWaalsContact O-CB 3.26Å; M247-K250 WeakPolarHBondContact O-CB 3.47Å; M247-K250 PolarHBondContact O-N 3.48Å; M247-K250 VanDerWaalsContact O-N 3.13Å; V248-K250 VanDerWaalsContact C-N 3.27Å; V248-K250 PolarHBondContact O-N 3.24Å; K250-T252 VanDerWaalsContact C-N 3.26Å; K250-T252 PolarHBondContact O-N 2.94Å; K250-G253 PolarHBondContact O-N 3.14Å; K250-K254 WeakPolarHBondContact CA-O 3.26Å; K250-F256 HydrophobicContact CD-CE1 3.92Å; K250-F256 HydrophobicContact CD-CZ 4.23Å
251A93.1Very high93.9Very high60 Ų6057.6 Ų57.650%0.49630%0.299SS..Hα-helixtrans-65.9-25.7178.900000113.6F211 M247 V248 N249F211-A251 HydrophobicContact CZ-CB 4.24Å; M247-A251 PolarHBondContact O-N 3.01Å; M247-A251 VanDerWaalsContact O-N 3.09Å; V248-A251 WeakPolarHBondContact O-CB 3.44Å; V248-A251 PolarHBondContact O-N 3.17Å; V248-A251 VanDerWaalsContact O-N 3.17Å; N249-A251 VanDerWaalsContact C-N 3.32Å; N249-A251 PolarHBondContact O-N 2.63Å
252T93.5Very high93.7Very high99 Ų9958 Ų5861%0.60730%0.301SS*.THydrogen-bonded Turntrans-97.62317863.60000113.3V248 N249 K250 K254V248-T252 PolarHBondContact O-N 3.02Å; N249-T252 PolarHBondContact O-N 3.35Å; N249-T252 PolarHBondContact O-OG1 3.49Å; N249-T252 VanDerWaalsContact O-OG1 3.11Å; K250-T252 VanDerWaalsContact C-N 3.26Å; K250-T252 PolarHBondContact O-N 2.94Å; T252-K254 PolarHBondContact O-N 2.81Å
253G91.2Very high93.4Very high39 Ų3962.2 Ų62.240%0.40232%0.323SS..THydrogen-bonded Turntrans83.93.7176.600000115.9L208 G210 K250L208-G253 CarbonylContact C-O 3.56Å; G210-G253 PolarHBondContact N-O 3.25Å; K250-G253 PolarHBondContact O-N 3.14Å
254K94.4Very high93.3Very high60 Ų6062.3 Ų62.326%0.26133%0.329SS..  trans-100.3-141.2170.3-51.8-171.7-177.4-176.30109.3Q206 P207 L208 G210 N249 K250 T252 D339Q206-K254 HydrophobicContact CG-CB 4.21Å; Q206-K254 HydrophobicContact CG-CD 4.45Å; Q206-K254 VanDerWaalsContact NE2-CD 3.34Å; Q206-K254 VanDerWaalsContact OE1-CB 3.25Å; P207-K254 CarbonylContact O-C 3.47Å; L208-K254 HydrophobicContact CD2-CB 4.46Å; L208-K254 HydrophobicContact CD2-CG 3.94Å; G210-K254 WeakPolarHBondContact CA-O 3.03Å; G210-K254 PolarHBondContact N-O 2.54Å; N249-K254 HydrophobicContact CB-CB 4.22Å; N249-K254 CarbonylContact O-C 3.49Å; N249-K254 WeakPolarHBondContact O-CA 3.34Å; N249-K254 WeakPolarHBondContact O-CB 3.31Å; N249-K254 PolarHBondContact O-N 3.38Å; K250-K254 WeakPolarHBondContact CA-O 3.26Å; T252-K254 PolarHBondContact O-N 2.81Å; K254-D339 IonicContact NZ-OD1 3.4Å
255G93.1Very high93.4Very high0 Ų057.2 Ų57.20%030%0.303CS..  trans133.7-136.6169.200000112.9Q206 P207 R241Q206-G255 WeakPolarHBondContact CB-O 3.3Å; Q206-G255 PolarHBondContact OE1-O 3.2Å; P207-G255 PolarHBondContact O-N 3.35Å; R241-G255 PolarHBondContact NH2-O 3.11Å
256F94.8Very high93.5Very high36 Ų3662.2 Ų62.216%0.15832%0.319CS..  trans-150.4160.1-173.454.2-88.5000110.3A246 K250 Y267 F269A246-F256 HydrophobicContact CB-CD1 3.92Å; A246-F256 HydrophobicContact CB-CE1 4.36Å; K250-F256 HydrophobicContact CD-CE1 3.92Å; K250-F256 HydrophobicContact CD-CZ 4.23Å; F256-Y267 HydrophobicContact CB-CE1 4.36Å; F256-Y267 HydrophobicContact CB-CE2 4.38Å; F256-Y267 WeakPolarHBondContact CB-OH 3.41Å; F256-F269 HydrophobicContact CB-CZ 4.38Å; F256-F269 HydrophobicContact CD1-CE1 4.49Å; F256-F269 HydrophobicContact CD1-CZ 4.09Å; F256-F269 AromaticContact CD2-CZ 3.82Å; F256-F269 HydrophobicContact CD2-CZ 3.82Å; F256-F269 HydrophobicContact CE1-CZ 4.28Å; F256-F269 HydrophobicContact CE2-CZ 4.04Å; F256-F269 HydrophobicContact CG-CE1 4.43Å; F256-F269 AromaticContact CG-CZ 3.86Å; F256-F269 HydrophobicContact CG-CZ 3.86Å; F256-F269 HydrophobicContact CZ-CZ 4.26Å
257E93.9Very high93.5Very high5 Ų563.6 Ų63.62%0.02333%0.325CS..  trans-63.2141.6179-65.286.7153.600111.3R182 P207 I237 Y262 Y267 H336R182-E257 IonicContact CZ-OE1 2.95Å; R182-E257 IonicContact NH1-OE1 3.4Å; R182-E257 PolarHBondContact NH1-OE1 2.93Å; R182-E257 IonicContact NH2-OE1 3.26Å; R182-E257 PolarHBondContact NH2-OE1 3.42Å; P207-E257 WeakPolarHBondContact CD-OE2 3.23Å; P207-E257 HydrophobicContact CG-CG 4.2Å; I237-E257 HydrophobicContact CD1-CB 4.11Å; I237-E257 HydrophobicContact CD1-CG 3.86Å; E257-Y262 HydrophobicContact CB-CD2 3.72Å; E257-Y262 HydrophobicContact CB-CE2 3.51Å; E257-Y262 HydrophobicContact CB-CG 4.34Å; E257-Y262 HydrophobicContact CG-CD1 4.43Å; E257-Y262 HydrophobicContact CG-CD2 4.15Å; E257-Y262 HydrophobicContact CG-CE1 3.92Å; E257-Y262 HydrophobicContact CG-CE2 3.62Å; E257-Y262 VanDerWaalsContact CG-CZ 3.48Å; E257-Y267 HydrophobicContact CB-CD2 4.24Å; E257-Y267 HydrophobicContact CB-CE2 3.87Å; E257-Y267 WeakPolarHBondContact OE2-CE2 3.48Å; E257-Y267 PolarHBondContact OE2-OH 3.05Å; E257-H336 IonicContact OE1-NE2 3.13Å; E257-H336 IonicContact OE2-CE1 3.12Å; E257-H336 IonicContact OE2-NE2 3.91Å; E257-H336 PolarHBondContact OE2-NE2 3.3Å
258D91.4Very high93.6Very high39 Ų3961.5 Ų61.521%0.20931%0.314CS..  trans-101.1117.1176.2-171.5-32.2000109.4R260 N261 Y262D258-R260 PolarHBondContact O-N 3.42Å; D258-R260 VanDerWaalsContact OD1-CB 3.31Å; D258-R260 WeakPolarHBondContact OD1-CB 3.44Å; D258-R260 WeakPolarHBondContact OD1-CG 3.32Å; D258-R260 IonicContact OD1-CZ 2.82Å; D258-R260 PolarHBondContact OD1-N 3.01Å; D258-R260 IonicContact OD1-NE 3.56Å; D258-R260 PolarHBondContact OD1-NE 2.89Å; D258-R260 IonicContact OD1-NH2 2.87Å; D258-R260 IonicContact OD2-CZ 3.55Å; D258-R260 VanDerWaalsContact OD2-CZ 3.29Å; D258-R260 IonicContact OD2-NE 3.75Å; D258-R260 PolarHBondContact OD2-NE 3.13Å; D258-R260 VanDerWaalsContact OD2-NE 3.14Å; D258-R260 IonicContact OD2-NH2 3.72Å; D258-R260 PolarHBondContact OD2-NH2 3.47Å; D258-N261 PolarHBondContact O-N 3.25Å; D258-Y262 WeakPolarHBondContact O-CD2 3.5Å; D258-Y262 PolarHBondContact O-N 3.24Å
259E90.4Very high93.7Very high80 Ų8060.2 Ų60.237%0.37430%0.301SS..THydrogen-bonded Turntrans-52.4-24.8-178.2-68.4-169.4171.100113.3N261 R266 Y267E259-N261 PolarHBondContact O-N 3.44Å; E259-R266 WeakPolarHBondContact OE1-CA 3.5Å; E259-R266 IonicContact OE2-NH1 3.31Å; E259-Y267 WeakPolarHBondContact OE1-CB 3.46Å; E259-Y267 PolarHBondContact OE1-N 2.61Å
260R91.7Very high93.9Very high203 Ų20360.2 Ų60.277%0.76630%0.3SS*.THydrogen-bonded Turntrans-66.9-25.8175.9-60.1176.4-67.6173.72.4113.4D258D258-R260 PolarHBondContact O-N 3.42Å; D258-R260 VanDerWaalsContact OD1-CB 3.31Å; D258-R260 WeakPolarHBondContact OD1-CB 3.44Å; D258-R260 WeakPolarHBondContact OD1-CG 3.32Å; D258-R260 IonicContact OD1-CZ 2.82Å; D258-R260 PolarHBondContact OD1-N 3.01Å; D258-R260 IonicContact OD1-NE 3.56Å; D258-R260 PolarHBondContact OD1-NE 2.89Å; D258-R260 IonicContact OD1-NH2 2.87Å; D258-R260 IonicContact OD2-CZ 3.55Å; D258-R260 VanDerWaalsContact OD2-CZ 3.29Å; D258-R260 IonicContact OD2-NE 3.75Å; D258-R260 PolarHBondContact OD2-NE 3.13Å; D258-R260 VanDerWaalsContact OD2-NE 3.14Å; D258-R260 IonicContact OD2-NH2 3.72Å; D258-R260 PolarHBondContact OD2-NH2 3.47Å
261N93.2Very high94Very high32 Ų3260.3 Ų60.317%0.17131%0.309CS..THydrogen-bonded Turntrans-97.4-26.6-178.8-62.8-30.3000112.2R214 D258 E259R214-N261 PolarHBondContact NE-OD1 3Å; R214-N261 PolarHBondContact NH1-OD1 3.11Å; D258-N261 PolarHBondContact O-N 3.25Å; E259-N261 PolarHBondContact O-N 3.44Å
262Y94.7Very high94.2Very high10 Ų1057.6 Ų57.64%0.03929%0.286CS..SBendtrans-103.894.8-178.3-65.7-99.7000110.6D218 E219 M222 E257 D258 V265D218-Y262 PolarHBondContact OD2-OH 3.3Å; E219-Y262 HydrophobicContact CB-CD1 4.41Å; E219-Y262 HydrophobicContact CB-CE1 4.29Å; E219-Y262 HydrophobicContact CG-CD1 4.14Å; E219-Y262 HydrophobicContact CG-CD2 4.47Å; E219-Y262 HydrophobicContact CG-CE1 3.86Å; E219-Y262 HydrophobicContact CG-CE2 4.2Å; E219-Y262 HydrophobicContact CG-CG 4.45Å; M222-Y262 HydrophobicContact CB-CD1 4.04Å; M222-Y262 HydrophobicContact CB-CE1 4.44Å; M222-Y262 HydrophobicContact CG-CD1 3.75Å; M222-Y262 HydrophobicContact CG-CE1 3.76Å; E257-Y262 HydrophobicContact CB-CD2 3.72Å; E257-Y262 HydrophobicContact CB-CE2 3.51Å; E257-Y262 HydrophobicContact CB-CG 4.34Å; E257-Y262 HydrophobicContact CG-CD1 4.43Å; E257-Y262 HydrophobicContact CG-CD2 4.15Å; E257-Y262 HydrophobicContact CG-CE1 3.92Å; E257-Y262 HydrophobicContact CG-CE2 3.62Å; E257-Y262 VanDerWaalsContact CG-CZ 3.48Å; D258-Y262 WeakPolarHBondContact O-CD2 3.5Å; D258-Y262 PolarHBondContact O-N 3.24Å; Y262-V265 WeakPolarHBondContact O-CB 3.48Å; Y262-V265 PolarHBondContact O-N 2.86Å
263N90.4Very high94.4Very high102 Ų10255.4 Ų55.455%0.54527%0.269SS..THydrogen-bonded Turntrans-58138.7-179.9-65.1-16.6000112.1V265N263-V265 PolarHBondContact O-N 3.43Å
264N93.7Very high94.7Very high122 Ų12255.9 Ų55.965%0.65226%0.262SS*.THydrogen-bonded Turntrans57.529.5177.7-56.1-30.7000113.8T234 L235T234-N264 CarbonylContact C-O 3.48Å; T234-N264 VanDerWaalsContact CA-O 3.29Å; T234-N264 WeakPolarHBondContact CA-O 3.28Å; L235-N264 PolarHBondContact N-O 2.79Å
265V95.7Very high94.9Very high11 Ų1153.8 Ų53.87%0.06725%0.254CS..EExtended strand (participates in β ladder)trans-107.1144.2174.2169.10000110.7L235 I237 Y262 N263L235-V265 HydrophobicContact CB-CG2 4.17Å; L235-V265 HydrophobicContact CD2-CG2 4.22Å; L235-V265 CarbonylContact O-C 3.54Å; L235-V265 VanDerWaalsContact O-CA 3.24Å; L235-V265 WeakPolarHBondContact O-CA 3.3Å; I237-V265 HydrophobicContact CB-CG1 4.25Å; I237-V265 HydrophobicContact CD1-CG1 3.55Å; I237-V265 HydrophobicContact CD1-CG2 4.46Å; I237-V265 HydrophobicContact CG1-CG1 3.6Å; Y262-V265 WeakPolarHBondContact O-CB 3.48Å; Y262-V265 PolarHBondContact O-N 2.86Å; N263-V265 PolarHBondContact O-N 3.43Å
266R96.1Very high95Very high144 Ų14457.7 Ų57.754%0.54327%0.272SS..EExtended strand (participates in β ladder)trans-121.6135.2166.1-68.2-67.5-172.5-176.82110.5T234 L235 F236 I237 E259T234-R266 HydrophobicContact CG2-CB 4.05Å; T234-R266 HydrophobicContact CG2-CG 3.54Å; L235-R266 PolarHBondContact O-N 3.16Å; F236-R266 CarbonylContact C-O 3.53Å; F236-R266 WeakPolarHBondContact CA-O 3.19Å; F236-R266 HydrophobicContact CD1-CB 3.75Å; F236-R266 HydrophobicContact CD1-CG 4.49Å; F236-R266 HydrophobicContact CE1-CB 3.85Å; F236-R266 HydrophobicContact CE1-CG 4.2Å; I237-R266 PolarHBondContact N-O 2.83Å; E259-R266 WeakPolarHBondContact OE1-CA 3.5Å; E259-R266 IonicContact OE2-NH1 3.31Å
267Y94Very high95.2Very high28 Ų2857.4 Ų57.411%0.1128%0.277CS..EExtended strand (participates in β ladder)trans-106.7132.1-172.3-153-84.1000111.6I237 D239 F256 E257 E259 F269 H336I237-Y267 HydrophobicContact CB-CD2 3.69Å; I237-Y267 HydrophobicContact CB-CE2 3.86Å; I237-Y267 HydrophobicContact CD1-CD2 4.49Å; I237-Y267 HydrophobicContact CG2-CD2 3.75Å; I237-Y267 HydrophobicContact CG2-CE2 3.34Å; I237-Y267 WeakPolarHBondContact O-CA 3.31Å; D239-Y267 HydrophobicContact CB-CE1 3.5Å; D239-Y267 VanDerWaalsContact CB-CE1 3.5Å; D239-Y267 VanDerWaalsContact CB-OH 3.24Å; D239-Y267 WeakPolarHBondContact CB-OH 3.49Å; D239-Y267 PolarHBondContact OD2-OH 2.83Å; F256-Y267 HydrophobicContact CB-CE1 4.36Å; F256-Y267 HydrophobicContact CB-CE2 4.38Å; F256-Y267 WeakPolarHBondContact CB-OH 3.41Å; E257-Y267 HydrophobicContact CB-CD2 4.24Å; E257-Y267 HydrophobicContact CB-CE2 3.87Å; E257-Y267 WeakPolarHBondContact OE2-CE2 3.48Å; E257-Y267 PolarHBondContact OE2-OH 3.05Å; E259-Y267 WeakPolarHBondContact OE1-CB 3.46Å; E259-Y267 PolarHBondContact OE1-N 2.61Å; Y267-F269 AromaticContact CD1-CD2 3.83Å; Y267-F269 HydrophobicContact CD1-CD2 3.83Å; Y267-F269 HydrophobicContact CD1-CE1 4.39Å; Y267-F269 AromaticContact CD1-CE2 3.46Å; Y267-F269 HydrophobicContact CD1-CE2 3.46Å; Y267-F269 VanDerWaalsContact CD1-CE2 3.46Å; Y267-F269 HydrophobicContact CD1-CG 4.45Å; Y267-F269 AromaticContact CD1-CZ 3.78Å; Y267-F269 HydrophobicContact CD1-CZ 3.78Å; Y267-F269 HydrophobicContact CE1-CD1 4.04Å; Y267-F269 AromaticContact CE1-CD2 3.95Å; Y267-F269 HydrophobicContact CE1-CD2 3.95Å; Y267-F269 AromaticContact CE1-CE1 3.56Å; Y267-F269 HydrophobicContact CE1-CE1 3.56Å; Y267-F269 AromaticContact CE1-CE2 3.47Å; Y267-F269 HydrophobicContact CE1-CE2 3.47Å; Y267-F269 VanDerWaalsContact CE1-CE2 3.47Å; Y267-F269 HydrophobicContact CE1-CG 4.23Å; Y267-F269 AromaticContact CE1-CZ 3.26Å; Y267-F269 HydrophobicContact CE1-CZ 3.26Å; Y267-H336 AromaticContact CZ-NE2 3.88Å; Y267-H336 PolarHBondContact OH-CE1 3Å; Y267-H336 PolarHBondContact OH-NE2 3.45Å
268H97.5Very high95.4Very high55 Ų5557.2 Ų57.226%0.25528%0.276SS..EExtended strand (participates in β ladder)trans-128.2123.1-178.9-63.5-90.7000110.4F236 I237 V238 D239 F270 F322F236-H268 AromaticContact CD2-NE2 3.95Å; F236-H268 AromaticContact CE2-NE2 3.97Å; I237-H268 PolarHBondContact O-N 3.4Å; V238-H268 WeakPolarHBondContact CA-O 3.24Å; V238-H268 HydrophobicContact CG2-CB 4.38Å; D239-H268 PolarHBondContact N-O 2.87Å; H268-F270 HydrophobicContact CB-CE2 3.86Å; H268-F322 HydrophobicContact CB-CE1 4.12Å; H268-F322 HydrophobicContact CB-CZ 4.2Å; H268-F322 AromaticContact CD2-CZ 3.75Å; H268-F322 AromaticContact CE1-CZ 3.65Å; H268-F322 AromaticContact CG-CE1 3.9Å; H268-F322 AromaticContact CG-CZ 3.55Å; H268-F322 AromaticContact ND1-CZ 3.48Å; H268-F322 WeakPolarHBondContact ND1-CZ 3.23Å; H268-F322 AromaticContact NE2-CZ 3.82Å
269F97.4Very high95.6Very high61 Ų6158.8 Ų58.827%0.26828%0.279SS..EExtended strand (participates in β ladder)trans-96.9138.4173-72.6-82.7000110.5D239 K243 A246 F256 Y267D239-F269 HydrophobicContact CB-CD1 3.74Å; D239-F269 HydrophobicContact CB-CE1 3.89Å; D239-F269 CarbonylContact O-C 3.52Å; D239-F269 WeakPolarHBondContact O-CA 3.37Å; D239-F269 WeakPolarHBondContact OD2-CE1 3.49Å; K243-F269 HydrophobicContact CB-CD1 4.37Å; K243-F269 HydrophobicContact CB-CG 4.24Å; K243-F269 HydrophobicContact CD-CD2 4.5Å; K243-F269 HydrophobicContact CG-CD2 4.25Å; K243-F269 HydrophobicContact CG-CE2 4.3Å; K243-F269 HydrophobicContact CG-CG 4.38Å; K243-F269 HydrophobicContact CG-CZ 4.46Å; A246-F269 HydrophobicContact CB-CD1 4.28Å; A246-F269 HydrophobicContact CB-CE1 3.51Å; A246-F269 HydrophobicContact CB-CZ 4.32Å; F256-F269 HydrophobicContact CB-CZ 4.38Å; F256-F269 HydrophobicContact CD1-CE1 4.49Å; F256-F269 HydrophobicContact CD1-CZ 4.09Å; F256-F269 AromaticContact CD2-CZ 3.82Å; F256-F269 HydrophobicContact CD2-CZ 3.82Å; F256-F269 HydrophobicContact CE1-CZ 4.28Å; F256-F269 HydrophobicContact CE2-CZ 4.04Å; F256-F269 HydrophobicContact CG-CE1 4.43Å; F256-F269 AromaticContact CG-CZ 3.86Å; F256-F269 HydrophobicContact CG-CZ 3.86Å; F256-F269 HydrophobicContact CZ-CZ 4.26Å; Y267-F269 AromaticContact CD1-CD2 3.83Å; Y267-F269 HydrophobicContact CD1-CD2 3.83Å; Y267-F269 HydrophobicContact CD1-CE1 4.39Å; Y267-F269 AromaticContact CD1-CE2 3.46Å; Y267-F269 HydrophobicContact CD1-CE2 3.46Å; Y267-F269 VanDerWaalsContact CD1-CE2 3.46Å; Y267-F269 HydrophobicContact CD1-CG 4.45Å; Y267-F269 AromaticContact CD1-CZ 3.78Å; Y267-F269 HydrophobicContact CD1-CZ 3.78Å; Y267-F269 HydrophobicContact CE1-CD1 4.04Å; Y267-F269 AromaticContact CE1-CD2 3.95Å; Y267-F269 HydrophobicContact CE1-CD2 3.95Å; Y267-F269 AromaticContact CE1-CE1 3.56Å; Y267-F269 HydrophobicContact CE1-CE1 3.56Å; Y267-F269 AromaticContact CE1-CE2 3.47Å; Y267-F269 HydrophobicContact CE1-CE2 3.47Å; Y267-F269 VanDerWaalsContact CE1-CE2 3.47Å; Y267-F269 HydrophobicContact CE1-CG 4.23Å; Y267-F269 AromaticContact CE1-CZ 3.26Å; Y267-F269 HydrophobicContact CE1-CZ 3.26Å
270F97.1Very high96Very high32 Ų3258.4 Ų58.414%0.1428%0.282CS..  trans-119.6165.8171.3-71.3-93.6000110.8V238 D239 T240 R241 P242 H268 T319 F322V238-F270 HydrophobicContact CG1-CD2 3.7Å; V238-F270 HydrophobicContact CG1-CE2 3.83Å; V238-F270 HydrophobicContact CG2-CE2 4.38Å; D239-F270 PolarHBondContact O-N 3.08Å; T240-F270 CarbonylContact C-O 3.58Å; T240-F270 CarbonylContact O-C 3.55Å; T240-F270 VanDerWaalsContact O-O 3.1Å; R241-F270 CarbonylContact C-O 3.58Å; P242-F270 WeakPolarHBondContact CA-O 3.48Å; H268-F270 HydrophobicContact CB-CE2 3.86Å; F270-T319 HydrophobicContact CB-CG2 3.99Å; F270-T319 VanDerWaalsContact CB-OG1 3.28Å; F270-T319 WeakPolarHBondContact CB-OG1 3.37Å; F270-T319 HydrophobicContact CD1-CG2 4.04Å; F270-T319 VanDerWaalsContact CD1-OG1 3.31Å; F270-T319 WeakPolarHBondContact CD1-OG1 3.08Å; F270-T319 HydrophobicContact CD2-CG2 3.86Å; F270-T319 HydrophobicContact CE2-CG2 4.41Å; F270-T319 HydrophobicContact CG-CG2 3.67Å; F270-T319 WeakPolarHBondContact CG-OG1 3.44Å; F270-F322 HydrophobicContact CE1-CB 3.93Å; F270-F322 HydrophobicContact CE1-CG 4.18Å; F270-F322 AromaticContact CE2-CD1 3.7Å; F270-F322 HydrophobicContact CE2-CD1 3.7Å; F270-F322 HydrophobicContact CE2-CE1 4.1Å; F270-F322 HydrophobicContact CE2-CG 4.14Å; F270-F322 HydrophobicContact CZ-CB 3.56Å; F270-F322 AromaticContact CZ-CD1 3.41Å; F270-F322 HydrophobicContact CZ-CD1 3.41Å; F270-F322 VanDerWaalsContact CZ-CD1 3.41Å; F270-F322 AromaticContact CZ-CD2 3.95Å; F270-F322 HydrophobicContact CZ-CD2 3.95Å; F270-F322 HydrophobicContact CZ-CE1 4.06Å; F270-F322 AromaticContact CZ-CG 3.35Å; F270-F322 HydrophobicContact CZ-CG 3.35Å
271A95.8Very high96.3Very high49 Ų4948.9 Ų48.941%0.40525%0.247SC..  trans-105.453.5-176.200000112P242 S315P242-A271 HydrophobicContact CG-CB 4.38Å; A271-S315 PolarHBondContact O-OG 3.3Å
272V98.3Very high96.5Very high3 Ų348 Ų482%0.01824%0.242CC..  trans-86.3112.8172.4-166.80000109.7T240 P242 L316 T319 R343 T347T240-V272 WeakPolarHBondContact O-CA 3.5Å; T240-V272 WeakPolarHBondContact O-CB 3.45Å; T240-V272 PolarHBondContact O-N 3.13Å; P242-V272 VanDerWaalsContact CD-O 3.27Å; P242-V272 WeakPolarHBondContact CD-O 3.24Å; V272-L316 HydrophobicContact CB-CD2 4.42Å; V272-L316 HydrophobicContact CG1-CD2 3.38Å; V272-L316 HydrophobicContact CG1-CG 4.31Å; V272-L316 HydrophobicContact CG2-CD2 4.11Å; V272-T319 WeakPolarHBondContact CG2-OG1 3.46Å; V272-R343 HydrophobicContact CB-CB 4.43Å; V272-R343 HydrophobicContact CB-CG 4.11Å; V272-R343 HydrophobicContact CG1-CB 4.07Å; V272-R343 HydrophobicContact CG1-CG 3.55Å; V272-R343 WeakPolarHBondContact O-CD 3.48Å; V272-R343 PolarHBondContact O-NH1 3.32Å; V272-T347 HydrophobicContact CG2-CG2 4.28Å
273E98Very high96.5Very high52 Ų5252.2 Ų52.224%0.24326%0.262CS..  trans-68.3158.7-172.2-75.7-54.3157.100114.2A277 V278 H312 R343E273-A277 HydrophobicContact CB-CB 3.81Å; E273-A277 HydrophobicContact CG-CB 4.16Å; E273-V278 HydrophobicContact CB-CG2 4.16Å; E273-H312 WeakPolarHBondContact CG-CE1 3.44Å; E273-R343 WeakPolarHBondContact O-CD 3.27Å
274N97.4Very high96.7Very high49 Ų4952.2 Ų52.226%0.26226%0.257SS..  trans-75.7171.3178.768.439.4000112.5H276 A277 V278N274-H276 PolarHBondContact O-N 3.42Å; N274-H276 PolarHBondContact OD1-N 3.47Å; N274-H276 VanDerWaalsContact OD1-N 3.09Å; N274-A277 PolarHBondContact O-N 2.8Å; N274-A277 PolarHBondContact OD1-N 3.07Å; N274-V278 WeakPolarHBondContact O-CG2 3.4Å; N274-V278 PolarHBondContact O-N 2.65Å
275I97.4Very high96.8Very high17 Ų1746.4 Ų46.49%0.08723%0.226CC..Hα-helixtrans-56.5-35.4-176.369.2173.8000113.2R279 D342 A396 I398I275-R279 WeakPolarHBondContact O-CB 3.4Å; I275-R279 PolarHBondContact O-N 3.36Å; I275-D342 HydrophobicContact CG2-CB 4.4Å; I275-D342 WeakPolarHBondContact CG2-OD2 3.31Å; I275-A396 HydrophobicContact CB-CB 3.59Å; I275-A396 HydrophobicContact CG2-CB 4.27Å; I275-A396 WeakPolarHBondContact O-CB 3.37Å; I275-I398 HydrophobicContact CB-CD1 4.45Å; I275-I398 HydrophobicContact CG2-CD1 3.98Å; I275-I398 HydrophobicContact CG2-CG1 4.14Å
276H96.9Very high96.6Very high81 Ų8146.2 Ų46.238%0.37523%0.225SC..Hα-helixtrans-72.4-46-178.1-51-49.9000111.4N274 R279 T280 K393N274-H276 PolarHBondContact O-N 3.42Å; N274-H276 PolarHBondContact OD1-N 3.47Å; N274-H276 VanDerWaalsContact OD1-N 3.09Å; H276-R279 PolarHBondContact O-N 3.14Å; H276-T280 PolarHBondContact O-N 2.95Å; H276-T280 PolarHBondContact O-OG1 2.86Å; H276-K393 PolarHBondContact CE1-O 3.07Å; H276-K393 PolarHBondContact ND1-O 3.12Å
277A97.6Very high96.3Very high31 Ų3143.5 Ų43.526%0.25622%0.221SC..Hα-helixtrans-62.9-42.4176.700000111.4E273 N274 T280 S281E273-A277 HydrophobicContact CB-CB 3.81Å; E273-A277 HydrophobicContact CG-CB 4.16Å; N274-A277 PolarHBondContact O-N 2.8Å; N274-A277 PolarHBondContact OD1-N 3.07Å; A277-T280 PolarHBondContact O-N 2.85Å; A277-S281 WeakPolarHBondContact O-CB 3.32Å; A277-S281 PolarHBondContact O-N 2.98Å
278V98.2Very high96.1Very high0 Ų043.4 Ų43.40%022%0.223CC..Hα-helixtrans-64.6-43176.6176.10000111.6E273 N274 S281 L282 W309 P397 I398E273-V278 HydrophobicContact CB-CG2 4.16Å; N274-V278 WeakPolarHBondContact O-CG2 3.4Å; N274-V278 PolarHBondContact O-N 2.65Å; V278-S281 WeakPolarHBondContact O-CB 3.24Å; V278-S281 PolarHBondContact O-N 3.45Å; V278-L282 PolarHBondContact O-N 2.81Å; V278-W309 HydrophobicContact CG1-CH2 4.35Å; V278-W309 HydrophobicContact CG1-CZ3 3.83Å; V278-P397 HydrophobicContact CG1-CG 3.92Å; V278-I398 HydrophobicContact CB-CD1 4.37Å; V278-I398 HydrophobicContact CG1-CD1 4.24Å
279R96.9Very high95.6Very high72 Ų7241.5 Ų41.527%0.27222%0.215SC..Hα-helixtrans-59.7-50.5174.4174179.656.2-153.512.8111.8I275 H276 S281 L282 Q283 S392 K393 V395 A396I275-R279 WeakPolarHBondContact O-CB 3.4Å; I275-R279 PolarHBondContact O-N 3.36Å; H276-R279 PolarHBondContact O-N 3.14Å; R279-S281 VanDerWaalsContact C-N 3.28Å; R279-S281 PolarHBondContact O-N 2.94Å; R279-L282 PolarHBondContact O-N 2.87Å; R279-Q283 PolarHBondContact O-N 3.1Å; R279-S392 PolarHBondContact NH1-O 3.28Å; R279-K393 PolarHBondContact NH1-O 3.45Å; R279-K393 VanDerWaalsContact NH1-O 3.08Å; R279-V395 VanDerWaalsContact CD-O 3.31Å; R279-V395 WeakPolarHBondContact CD-O 2.9Å; R279-V395 PolarHBondContact NH1-O 3.44Å; R279-A396 HydrophobicContact CB-CB 4.44Å
280T97.7Very high94.9Very high72 Ų7242.2 Ų42.244%0.44222%0.216SC..Hα-helixtrans-62.6-38.3179-640000111.4H276 A277 Q283 K284H276-T280 PolarHBondContact O-N 2.95Å; H276-T280 PolarHBondContact O-OG1 2.86Å; A277-T280 PolarHBondContact O-N 2.85Å; T280-Q283 PolarHBondContact O-N 2.8Å; T280-K284 HydrophobicContact CG2-CD 4.26Å; T280-K284 WeakPolarHBondContact O-CG 3.5Å; T280-K284 PolarHBondContact O-N 3.04Å
281S98.5Very high93.9Very high4 Ų442.7 Ų42.73%0.02823%0.226CC..Hα-helixtrans-61.6-47.9176.7178.30000112.1A277 V278 R279 K284 M285 S307 W309 H312A277-S281 WeakPolarHBondContact O-CB 3.32Å; A277-S281 PolarHBondContact O-N 2.98Å; V278-S281 WeakPolarHBondContact O-CB 3.24Å; V278-S281 PolarHBondContact O-N 3.45Å; R279-S281 VanDerWaalsContact C-N 3.28Å; R279-S281 PolarHBondContact O-N 2.94Å; S281-K284 PolarHBondContact O-N 2.96Å; S281-M285 WeakPolarHBondContact O-CB 3.32Å; S281-M285 PolarHBondContact O-N 3.45Å; S281-S307 VanDerWaalsContact CA-O 3.28Å; S281-S307 WeakPolarHBondContact CA-O 3.28Å; S281-S307 WeakPolarHBondContact CB-O 3.48Å; S281-S307 PolarHBondContact OG-O 2.74Å; S281-W309 WeakPolarHBondContact OG-CA 3.48Å; S281-W309 PolarHBondContact OG-N 2.93Å; S281-W309 VanDerWaalsContact OG-N 3.11Å; S281-H312 PolarHBondContact OG-CD2 3.12Å; S281-H312 VanDerWaalsContact OG-CD2 3.24Å
282L96.9Very high92.7Very high14 Ų1447.3 Ų47.37%0.07324%0.237CC..Hα-helixtrans-60.4-48.3176.8-178.662.8000111.1F76 V278 R279 K284 M285 L286 W309 P397 Y504F76-L282 HydrophobicContact CE1-CD1 4.34Å; F76-L282 HydrophobicContact CE1-CD2 3.85Å; F76-L282 HydrophobicContact CE1-CG 4.43Å; F76-L282 HydrophobicContact CZ-CD1 4.34Å; F76-L282 HydrophobicContact CZ-CD2 4Å; V278-L282 PolarHBondContact O-N 2.81Å; R279-L282 PolarHBondContact O-N 2.87Å; L282-K284 VanDerWaalsContact C-N 3.34Å; L282-K284 PolarHBondContact O-N 3.05Å; L282-M285 HydrophobicContact CD1-CE 3.61Å; L282-M285 WeakPolarHBondContact O-CB 3.45Å; L282-M285 PolarHBondContact O-N 3.26Å; L282-M285 VanDerWaalsContact O-N 3.09Å; L282-L286 HydrophobicContact CD1-CD1 4.23Å; L282-L286 HydrophobicContact CD1-CD2 4.4Å; L282-L286 HydrophobicContact CD1-CG 4.11Å; L282-L286 HydrophobicContact CD2-CD1 4.47Å; L282-L286 HydrophobicContact CG-CD1 3.92Å; L282-L286 HydrophobicContact CG-CG 4.23Å; L282-L286 WeakPolarHBondContact O-CG 3.45Å; L282-L286 PolarHBondContact O-N 3.31Å; L282-W309 HydrophobicContact CB-CE3 3.89Å; L282-W309 HydrophobicContact CB-CH2 4.26Å; L282-W309 HydrophobicContact CB-CZ3 3.61Å; L282-W309 HydrophobicContact CD1-CD2 4.31Å; L282-W309 HydrophobicContact CD1-CE3 4.24Å; L282-W309 HydrophobicContact CD1-CH2 4.06Å; L282-W309 HydrophobicContact CD1-CZ2 4.16Å; L282-W309 HydrophobicContact CD1-CZ3 4.11Å; L282-W309 HydrophobicContact CG-CZ3 4.35Å; L282-P397 HydrophobicContact CB-CG 4.03Å; L282-P397 HydrophobicContact CD2-CB 3.47Å; L282-P397 VanDerWaalsContact CD2-CB 3.47Å; L282-P397 HydrophobicContact CD2-CG 3.44Å; L282-P397 VanDerWaalsContact CD2-CG 3.44Å; L282-P397 HydrophobicContact CG-CG 4.36Å; L282-Y504 HydrophobicContact CD1-CD1 4.45Å; L282-Y504 HydrophobicContact CD1-CE1 3.73Å
283Q94.4Very high91.1Very high97 Ų9752.6 Ų52.645%0.45326%0.259SS..Hα-helixtrans-57.1-48-179.8-174.461.355.300111.5R279 T280 M285 L286 D287R279-Q283 PolarHBondContact O-N 3.1Å; T280-Q283 PolarHBondContact O-N 2.8Å; Q283-M285 VanDerWaalsContact C-N 3.28Å; Q283-M285 PolarHBondContact O-N 2.91Å; Q283-L286 PolarHBondContact O-N 3.47Å; Q283-D287 PolarHBondContact NE2-OD1 3.45Å; Q283-D287 PolarHBondContact O-N 2.88Å
284K96.3Very high89.7Confident102 Ų10257.7 Ų57.744%0.44329%0.289SS..Hα-helixtrans-59.8-38.3176.8-74.2177.2175.7-176.40112.7T280 S281 L282 V288T280-K284 HydrophobicContact CG2-CD 4.26Å; T280-K284 WeakPolarHBondContact O-CG 3.5Å; T280-K284 PolarHBondContact O-N 3.04Å; S281-K284 PolarHBondContact O-N 2.96Å; L282-K284 VanDerWaalsContact C-N 3.34Å; L282-K284 PolarHBondContact O-N 3.05Å; K284-V288 VanDerWaalsContact O-CG2 3.28Å; K284-V288 WeakPolarHBondContact O-CG2 3.12Å; K284-V288 PolarHBondContact O-N 3.44Å
285M95.3Very high89Confident0 Ų057.9 Ų57.90%029%0.291CS..Hα-helixtrans-66.4-46.4177.8-173.5-77.8-63.100110.5S281 L282 Q283 D287 V288 V289 M304 W309 L499 Y504S281-M285 WeakPolarHBondContact O-CB 3.32Å; S281-M285 PolarHBondContact O-N 3.45Å; L282-M285 HydrophobicContact CD1-CE 3.61Å; L282-M285 WeakPolarHBondContact O-CB 3.45Å; L282-M285 PolarHBondContact O-N 3.26Å; L282-M285 VanDerWaalsContact O-N 3.09Å; Q283-M285 VanDerWaalsContact C-N 3.28Å; Q283-M285 PolarHBondContact O-N 2.91Å; M285-D287 PolarHBondContact O-N 2.95Å; M285-V288 PolarHBondContact O-N 3.01Å; M285-V288 VanDerWaalsContact O-N 3.14Å; M285-V289 WeakPolarHBondContact O-CG2 3.4Å; M285-V289 PolarHBondContact O-N 2.91Å; M285-V289 HydrophobicContact SD-CB 4.29Å; M285-V289 HydrophobicContact SD-CG2 3.44Å; M285-V289 WeakPolarHBondContact SD-CG2 3.49Å; M285-M304 HydrophobicContact CG-CE 3.95Å; M285-M304 HydrophobicContact CG-SD 3.91Å; M285-W309 HydrophobicContact CB-CB 3.93Å; M285-W309 HydrophobicContact CB-CG 4.37Å; M285-W309 HydrophobicContact CG-CB 3.92Å; M285-W309 HydrophobicContact CG-CG 4.18Å; M285-L499 HydrophobicContact CE-CD1 4.42Å; M285-L499 HydrophobicContact SD-CD1 3.65Å; M285-Y504 HydrophobicContact CE-CD1 3.53Å; M285-Y504 HydrophobicContact CE-CD2 3.79Å; M285-Y504 HydrophobicContact CE-CE1 3.67Å; M285-Y504 HydrophobicContact CE-CE2 3.92Å; M285-Y504 HydrophobicContact CE-CG 3.6Å; M285-Y504 HydrophobicContact SD-CD2 4.49Å; M285-Y504 HydrophobicContact SD-CG 4.42Å
286L91.8Very high88.6Confident8 Ų860.4 Ų60.44%0.04231%0.311CS..Hα-helixtrans-62.4-40.5176.6-63.9174.8000112.2F76 L282 Q283 V288 V289 W290 Y504F76-L286 HydrophobicContact CD1-CD1 3.61Å; F76-L286 HydrophobicContact CD1-CD2 3.79Å; F76-L286 HydrophobicContact CD1-CG 4.35Å; F76-L286 HydrophobicContact CE1-CD1 3.72Å; F76-L286 HydrophobicContact CE1-CD2 4.22Å; F76-L286 HydrophobicContact CG-CD2 4.27Å; L282-L286 HydrophobicContact CD1-CD1 4.23Å; L282-L286 HydrophobicContact CD1-CD2 4.4Å; L282-L286 HydrophobicContact CD1-CG 4.11Å; L282-L286 HydrophobicContact CD2-CD1 4.47Å; L282-L286 HydrophobicContact CG-CD1 3.92Å; L282-L286 HydrophobicContact CG-CG 4.23Å; L282-L286 WeakPolarHBondContact O-CG 3.45Å; L282-L286 PolarHBondContact O-N 3.31Å; Q283-L286 PolarHBondContact O-N 3.47Å; L286-V288 PolarHBondContact O-N 3.09Å; L286-V289 PolarHBondContact O-N 3.21Å; L286-W290 HydrophobicContact CB-CD2 4.21Å; L286-W290 HydrophobicContact CB-CE3 3.98Å; L286-W290 HydrophobicContact CB-CH2 4.08Å; L286-W290 HydrophobicContact CB-CZ2 4.26Å; L286-W290 HydrophobicContact CB-CZ3 3.92Å; L286-W290 HydrophobicContact CD1-CH2 3.75Å; L286-W290 HydrophobicContact CD1-CZ2 4.22Å; L286-W290 HydrophobicContact CD1-CZ3 4.19Å; L286-W290 HydrophobicContact CD2-CH2 4.02Å; L286-W290 HydrophobicContact CD2-CZ2 3.6Å; L286-W290 HydrophobicContact CG-CH2 4.15Å; L286-W290 HydrophobicContact CG-CZ2 4.22Å; L286-W290 HydrophobicContact CG-CZ3 4.47Å; L286-W290 WeakPolarHBondContact O-CB 3.34Å; L286-W290 PolarHBondContact O-N 2.83Å; L286-Y504 HydrophobicContact CD2-CD1 3.87Å
287D89.7Confident88.4Confident87 Ų8762.7 Ų62.747%0.46532%0.323SS..Hα-helixtrans-58.2-33.8175.9-65.5-20.6000111.7Q283 M285 A291Q283-D287 PolarHBondContact NE2-OD1 3.45Å; Q283-D287 PolarHBondContact O-N 2.88Å; M285-D287 PolarHBondContact O-N 2.95Å; D287-A291 VanDerWaalsContact O-CB 3.22Å; D287-A291 WeakPolarHBondContact O-CB 3.4Å; D287-A291 PolarHBondContact O-N 3.3Å; D287-A291 VanDerWaalsContact O-N 3.12Å
288V90Very high88.2Confident25 Ų2567.1 Ų67.115%0.15234%0.342CS..Hα-helixtrans-80.3-44.1177.6175.40000111.4K284 M285 L286 W290 A291 F300 M304K284-V288 VanDerWaalsContact O-CG2 3.28Å; K284-V288 WeakPolarHBondContact O-CG2 3.12Å; K284-V288 PolarHBondContact O-N 3.44Å; M285-V288 PolarHBondContact O-N 3.01Å; M285-V288 VanDerWaalsContact O-N 3.14Å; L286-V288 PolarHBondContact O-N 3.09Å; V288-W290 VanDerWaalsContact C-N 3.32Å; V288-W290 PolarHBondContact O-N 2.93Å; V288-A291 WeakPolarHBondContact O-CB 3.25Å; V288-A291 PolarHBondContact O-N 2.94Å; V288-F300 HydrophobicContact CG1-CD2 3.65Å; V288-F300 HydrophobicContact CG1-CE2 4.05Å; V288-F300 HydrophobicContact CG1-CG 4.37Å; V288-M304 HydrophobicContact CG1-CG 4.23Å; V288-M304 HydrophobicContact CG1-SD 4.39Å
289V86.8Confident88Confident15 Ų1570.2 Ų70.29%0.09136%0.364CS..Hα-helixtrans-67.7-33.7-178.9170.80000111.9M285 L286 F300 M304 L499 N505M285-V289 WeakPolarHBondContact O-CG2 3.4Å; M285-V289 PolarHBondContact O-N 2.91Å; M285-V289 HydrophobicContact SD-CB 4.29Å; M285-V289 HydrophobicContact SD-CG2 3.44Å; M285-V289 WeakPolarHBondContact SD-CG2 3.49Å; L286-V289 PolarHBondContact O-N 3.21Å; V289-F300 HydrophobicContact CG2-CE2 4.45Å; V289-M304 HydrophobicContact CG2-SD 4.19Å; V289-L499 HydrophobicContact CG2-CD1 4.36Å; V289-L499 HydrophobicContact CG2-CD2 3.77Å; V289-N505 VanDerWaalsContact CG1-ND2 3.29Å; V289-N505 WeakPolarHBondContact CG1-ND2 3.47Å; V289-N505 WeakPolarHBondContact CG1-OD1 3.3Å
290W82.4Confident87.8Confident77 Ų7769.8 Ų69.829%0.29236%0.364SS..THydrogen-bonded Turntrans-98.83.2176.8-53.9-25.2000113.4F76 L286 V288 K292 Y504F76-W290 VanDerWaalsContact CA-CZ2 3.48Å; F76-W290 HydrophobicContact CB-CH2 4.23Å; F76-W290 HydrophobicContact CB-CZ2 3.59Å; F76-W290 HydrophobicContact CD1-CH2 4.26Å; F76-W290 HydrophobicContact CD1-CZ2 4.2Å; F76-W290 HydrophobicContact CG-CZ2 4.29Å; F76-W290 WeakPolarHBondContact O-CZ2 3.44Å; L286-W290 HydrophobicContact CB-CD2 4.21Å; L286-W290 HydrophobicContact CB-CE3 3.98Å; L286-W290 HydrophobicContact CB-CH2 4.08Å; L286-W290 HydrophobicContact CB-CZ2 4.26Å; L286-W290 HydrophobicContact CB-CZ3 3.92Å; L286-W290 HydrophobicContact CD1-CH2 3.75Å; L286-W290 HydrophobicContact CD1-CZ2 4.22Å; L286-W290 HydrophobicContact CD1-CZ3 4.19Å; L286-W290 HydrophobicContact CD2-CH2 4.02Å; L286-W290 HydrophobicContact CD2-CZ2 3.6Å; L286-W290 HydrophobicContact CG-CH2 4.15Å; L286-W290 HydrophobicContact CG-CZ2 4.22Å; L286-W290 HydrophobicContact CG-CZ3 4.47Å; L286-W290 WeakPolarHBondContact O-CB 3.34Å; L286-W290 PolarHBondContact O-N 2.83Å; V288-W290 VanDerWaalsContact C-N 3.32Å; V288-W290 PolarHBondContact O-N 2.93Å; W290-K292 PolarHBondContact O-N 3.34Å; W290-Y504 PolarHBondContact NE1-O 3.2Å
291A76.5Confident87.7Confident42 Ų4270.7 Ų70.735%0.34737%0.366SS..SBendtrans-59.3142.817100000109.5D287 V288 V295D287-A291 VanDerWaalsContact O-CB 3.22Å; D287-A291 WeakPolarHBondContact O-CB 3.4Å; D287-A291 PolarHBondContact O-N 3.3Å; D287-A291 VanDerWaalsContact O-N 3.12Å; V288-A291 WeakPolarHBondContact O-CB 3.25Å; V288-A291 PolarHBondContact O-N 2.94Å; A291-V295 HydrophobicContact CB-CG2 3.43Å; A291-V295 VanDerWaalsContact CB-CG2 3.43Å
292K69Low87.5Confident145 Ų14574.3 Ų74.363%0.6339%0.388SS*.  trans-46.5149.7-173.8-59.2179.6179.7-1780112W290 N294 V295W290-K292 PolarHBondContact O-N 3.34Å; K292-N294 PolarHBondContact O-N 3.05Å; K292-V295 WeakPolarHBondContact O-CG2 3.47Å; K292-V295 PolarHBondContact O-N 3.24Å; K292-V295 VanDerWaalsContact O-N 3.16Å
293K64.6Low87.5Confident114 Ų11474.3 Ų74.350%0.49639%0.392SS..THydrogen-bonded Turntrans-46.4-15.1-177.6-78-173.4172.4-178.20117.3C20 S510C20-K293 HydrophobicContact CB-CD 3.94Å; C20-K293 HydrophobicContact CB-CG 4.04Å; K293-S510 WeakPolarHBondContact CE-OG 3.2Å
294N69.9Low87.6Confident160 Ų16070.6 Ų70.686%0.85637%0.374SS*.THydrogen-bonded Turntrans-95.516.6-178-62.6-13.4000114.6K292 S296K292-N294 PolarHBondContact O-N 3.05Å; N294-S296 PolarHBondContact O-N 2.7Å
295V81.3Confident87.6Confident53 Ų5371.1 Ų71.132%0.32139%0.386SS..  trans-67.4122.6172.3176.70000109.7A291 K292 F300A291-V295 HydrophobicContact CB-CG2 3.43Å; A291-V295 VanDerWaalsContact CB-CG2 3.43Å; K292-V295 WeakPolarHBondContact O-CG2 3.47Å; K292-V295 PolarHBondContact O-N 3.24Å; K292-V295 VanDerWaalsContact O-N 3.16Å; V295-F300 HydrophobicContact CG1-CB 3.85Å
296S90.2Very high87.7Confident70 Ų7076.1 Ų76.149%0.4941%0.413SS..  trans-66.2152.2173.170.60000111.1N294 N298 S299 F300N294-S296 PolarHBondContact O-N 2.7Å; S296-N298 PolarHBondContact O-N 2.94Å; S296-N298 VanDerWaalsContact O-N 3.17Å; S296-S299 WeakPolarHBondContact O-CB 3.43Å; S296-S299 PolarHBondContact O-N 2.75Å; S296-S299 WeakPolarHBondContact OG-CB 3.49Å; S296-S299 PolarHBondContact OG-N 2.94Å; S296-F300 PolarHBondContact O-N 3.43Å
297M91.9Very high88Confident128 Ų12876 Ų7663%0.63141%0.412SS*.Hα-helixtrans-52.1-42178-175.657.266.100112.6S299 F300 L301M297-S299 PolarHBondContact O-N 3.47Å; M297-F300 PolarHBondContact O-N 3.24Å; M297-L301 HydrophobicContact CG-CD1 3.96Å; M297-L301 HydrophobicContact CG-CG 4.36Å; M297-L301 WeakPolarHBondContact O-CB 3.47Å; M297-L301 VanDerWaalsContact O-CG 3.3Å; M297-L301 WeakPolarHBondContact O-CG 3.45Å; M297-L301 PolarHBondContact O-N 3.16Å; M297-L301 HydrophobicContact SD-CD1 4.12Å; M297-L301 HydrophobicContact SD-CD2 4.46Å; M297-L301 HydrophobicContact SD-CG 4.03Å
298N94.5Very high88.4Confident124 Ų12472.5 Ų72.566%0.66340%0.397SS*.Hα-helixtrans-63.3-40.8178.1-70-21.4000112.5S296 T302S296-N298 PolarHBondContact O-N 2.94Å; S296-N298 VanDerWaalsContact O-N 3.17Å; N298-T302 WeakPolarHBondContact O-CB 3.29Å; N298-T302 PolarHBondContact O-N 3.38Å; N298-T302 PolarHBondContact O-OG1 2.91Å
299S93.6Very high88.8Confident66 Ų6671.3 Ų71.346%0.46239%0.39SS..Hα-helixtrans-67.8-42.3177.7-177.30000111.2S296 M297 T302 G303S296-S299 WeakPolarHBondContact O-CB 3.43Å; S296-S299 PolarHBondContact O-N 2.75Å; S296-S299 WeakPolarHBondContact OG-CB 3.49Å; S296-S299 PolarHBondContact OG-N 2.94Å; M297-S299 PolarHBondContact O-N 3.47Å; S299-T302 PolarHBondContact O-N 3.38Å; S299-G303 PolarHBondContact O-N 3Å
300F92.9Very high89.3Confident63 Ų6372.8 Ų72.828%0.27640%0.397SS..Hα-helixtrans-59.7-53175.1177.7-97.3000111.6V288 V289 V295 S296 M297 T302 G303 M304 L499V288-F300 HydrophobicContact CG1-CD2 3.65Å; V288-F300 HydrophobicContact CG1-CE2 4.05Å; V288-F300 HydrophobicContact CG1-CG 4.37Å; V289-F300 HydrophobicContact CG2-CE2 4.45Å; V295-F300 HydrophobicContact CG1-CB 3.85Å; S296-F300 PolarHBondContact O-N 3.43Å; M297-F300 PolarHBondContact O-N 3.24Å; F300-T302 PolarHBondContact O-N 2.66Å; F300-G303 PolarHBondContact O-N 2.77Å; F300-M304 HydrophobicContact CD1-CG 4.21Å; F300-M304 HydrophobicContact CD2-CG 4.47Å; F300-M304 HydrophobicContact CE1-CG 3.78Å; F300-M304 HydrophobicContact CE2-CG 4.07Å; F300-M304 HydrophobicContact CE2-SD 4.37Å; F300-M304 HydrophobicContact CZ-CG 3.69Å; F300-M304 HydrophobicContact CZ-SD 4.15Å; F300-M304 WeakPolarHBondContact O-CB 3.3Å; F300-M304 WeakPolarHBondContact O-CG 3.35Å; F300-M304 PolarHBondContact O-N 2.99Å; F300-L499 HydrophobicContact CZ-CD2 4.44Å
301L94.5Very high90.1Very high91 Ų9176.1 Ų76.148%0.47641%0.414SS..Hα-helixtrans-61.6-43.2-179.8-67.9174.8000111.8M297 M304 V305M297-L301 HydrophobicContact CG-CD1 3.96Å; M297-L301 HydrophobicContact CG-CG 4.36Å; M297-L301 WeakPolarHBondContact O-CB 3.47Å; M297-L301 VanDerWaalsContact O-CG 3.3Å; M297-L301 WeakPolarHBondContact O-CG 3.45Å; M297-L301 PolarHBondContact O-N 3.16Å; M297-L301 HydrophobicContact SD-CD1 4.12Å; M297-L301 HydrophobicContact SD-CD2 4.46Å; M297-L301 HydrophobicContact SD-CG 4.03Å; L301-M304 PolarHBondContact O-N 2.98Å; L301-V305 VanDerWaalsContact O-CG2 3.31Å; L301-V305 WeakPolarHBondContact O-CG2 3.09Å; L301-V305 PolarHBondContact O-N 3.23Å
302T96.1Very high91.1Very high79 Ų7975.3 Ų75.349%0.48540%0.403SS..Hα-helixtrans-62.2-44.7176.4-59.80000111.2N298 S299 F300 V305 N306N298-T302 WeakPolarHBondContact O-CB 3.29Å; N298-T302 PolarHBondContact O-N 3.38Å; N298-T302 PolarHBondContact O-OG1 2.91Å; S299-T302 PolarHBondContact O-N 3.38Å; F300-T302 PolarHBondContact O-N 2.66Å; T302-V305 PolarHBondContact O-N 2.66Å; T302-N306 WeakPolarHBondContact CG2-ND2 3.44Å; T302-N306 VanDerWaalsContact O-CB 3.26Å; T302-N306 WeakPolarHBondContact O-CB 3.47Å; T302-N306 PolarHBondContact O-N 2.98Å; T302-N306 PolarHBondContact O-ND2 3.46Å
303G96.1Very high92.5Very high15 Ų1568.4 Ų68.416%0.15537%0.373CS..Hα-helixtrans-60.7-45.817600000112.4S299 F300 V305 N306 S307S299-G303 PolarHBondContact O-N 3Å; F300-G303 PolarHBondContact O-N 2.77Å; G303-V305 PolarHBondContact O-N 3.03Å; G303-N306 PolarHBondContact O-N 3.36Å; G303-S307 PolarHBondContact O-N 3.21Å
304M95.4Very high94.1Very high18 Ų1866.3 Ų66.39%0.08936%0.362CS..Hα-helixtrans-60.2-46.5176.3-75.5-58.4-63.900111.9M285 V288 V289 F300 L301 S307 L310 L499M285-M304 HydrophobicContact CG-CE 3.95Å; M285-M304 HydrophobicContact CG-SD 3.91Å; V288-M304 HydrophobicContact CG1-CG 4.23Å; V288-M304 HydrophobicContact CG1-SD 4.39Å; V289-M304 HydrophobicContact CG2-SD 4.19Å; F300-M304 HydrophobicContact CD1-CG 4.21Å; F300-M304 HydrophobicContact CD2-CG 4.47Å; F300-M304 HydrophobicContact CE1-CG 3.78Å; F300-M304 HydrophobicContact CE2-CG 4.07Å; F300-M304 HydrophobicContact CE2-SD 4.37Å; F300-M304 HydrophobicContact CZ-CG 3.69Å; F300-M304 HydrophobicContact CZ-SD 4.15Å; F300-M304 WeakPolarHBondContact O-CB 3.3Å; F300-M304 WeakPolarHBondContact O-CG 3.35Å; F300-M304 PolarHBondContact O-N 2.99Å; L301-M304 PolarHBondContact O-N 2.98Å; M304-S307 WeakPolarHBondContact O-CB 3.37Å; M304-S307 PolarHBondContact O-N 3.08Å; M304-S307 PolarHBondContact O-OG 3.38Å; M304-L310 HydrophobicContact CE-CD1 4.03Å; M304-L310 HydrophobicContact CE-CG 4.21Å; M304-L499 HydrophobicContact CE-CB 4.39Å; M304-L499 HydrophobicContact CE-CD1 4.06Å; M304-L499 HydrophobicContact CE-CD2 4.43Å
305V96.3Very high95.5Very high113 Ų11359 Ų5969%0.68532%0.323SS*.Hα-helixtrans-60.9-46.1175.6169.80000111L301 T302 G303 S307 G308L301-V305 VanDerWaalsContact O-CG2 3.31Å; L301-V305 WeakPolarHBondContact O-CG2 3.09Å; L301-V305 PolarHBondContact O-N 3.23Å; T302-V305 PolarHBondContact O-N 2.66Å; G303-V305 PolarHBondContact O-N 3.03Å; V305-S307 VanDerWaalsContact C-N 3.28Å; V305-S307 PolarHBondContact O-N 3.07Å; V305-G308 PolarHBondContact O-N 2.74Å; V305-G308 VanDerWaalsContact O-N 3.14Å
306N97.8Very high96.3Very high106 Ų10656.5 Ų56.557%0.56731%0.308SS*.Hα-helixtrans-69.9-22.3-178.8-72.7-17.8000113.9T302 G303 G308T302-N306 WeakPolarHBondContact CG2-ND2 3.44Å; T302-N306 VanDerWaalsContact O-CB 3.26Å; T302-N306 WeakPolarHBondContact O-CB 3.47Å; T302-N306 PolarHBondContact O-N 2.98Å; T302-N306 PolarHBondContact O-ND2 3.46Å; G303-N306 PolarHBondContact O-N 3.36Å; N306-G308 VanDerWaalsContact C-N 3.28Å
307S98Very high96.8Very high5 Ų553.2 Ų53.24%0.03529%0.285CS..Hα-helixtrans-65.8-33.7171.979.90000111.6S281 G303 M304 V305 W309S281-S307 VanDerWaalsContact CA-O 3.28Å; S281-S307 WeakPolarHBondContact CA-O 3.28Å; S281-S307 WeakPolarHBondContact CB-O 3.48Å; S281-S307 PolarHBondContact OG-O 2.74Å; G303-S307 PolarHBondContact O-N 3.21Å; M304-S307 WeakPolarHBondContact O-CB 3.37Å; M304-S307 PolarHBondContact O-N 3.08Å; M304-S307 PolarHBondContact O-OG 3.38Å; V305-S307 VanDerWaalsContact C-N 3.28Å; V305-S307 PolarHBondContact O-N 3.07Å; S307-W309 PolarHBondContact O-N 2.97Å; S307-W309 PolarHBondContact OG-N 3.2Å
308G98.1Very high97.1Very high14 Ų1450.3 Ų50.314%0.14427%0.269CS..  trans69.42.8-173.700000115V305 N306 L310 K311 H312V305-G308 PolarHBondContact O-N 2.74Å; V305-G308 VanDerWaalsContact O-N 3.14Å; N306-G308 VanDerWaalsContact C-N 3.28Å; G308-L310 PolarHBondContact O-N 3.39Å; G308-K311 WeakPolarHBondContact O-CB 3.1Å; G308-K311 PolarHBondContact O-N 3.06Å; G308-K311 VanDerWaalsContact O-N 3.15Å; G308-H312 PolarHBondContact O-CD2 3.35Å; G308-H312 PolarHBondContact O-N 3.33Å
309W98.5Very high97.3Very high0 Ų044.4 Ų44.40%024%0.238CC..Hα-helixtrans-59.4-54.8-171.1-177.3-105.1000112.2V278 S281 L282 M285 S307 K311 H312 I313 P397 Q401 D404 Y504V278-W309 HydrophobicContact CG1-CH2 4.35Å; V278-W309 HydrophobicContact CG1-CZ3 3.83Å; S281-W309 WeakPolarHBondContact OG-CA 3.48Å; S281-W309 PolarHBondContact OG-N 2.93Å; S281-W309 VanDerWaalsContact OG-N 3.11Å; L282-W309 HydrophobicContact CB-CE3 3.89Å; L282-W309 HydrophobicContact CB-CH2 4.26Å; L282-W309 HydrophobicContact CB-CZ3 3.61Å; L282-W309 HydrophobicContact CD1-CD2 4.31Å; L282-W309 HydrophobicContact CD1-CE3 4.24Å; L282-W309 HydrophobicContact CD1-CH2 4.06Å; L282-W309 HydrophobicContact CD1-CZ2 4.16Å; L282-W309 HydrophobicContact CD1-CZ3 4.11Å; L282-W309 HydrophobicContact CG-CZ3 4.35Å; M285-W309 HydrophobicContact CB-CB 3.93Å; M285-W309 HydrophobicContact CB-CG 4.37Å; M285-W309 HydrophobicContact CG-CB 3.92Å; M285-W309 HydrophobicContact CG-CG 4.18Å; S307-W309 PolarHBondContact O-N 2.97Å; S307-W309 PolarHBondContact OG-N 3.2Å; W309-K311 PolarHBondContact O-N 3.02Å; W309-H312 WeakPolarHBondContact O-CA 3.42Å; W309-H312 WeakPolarHBondContact O-CB 3.33Å; W309-H312 PolarHBondContact O-N 2.87Å; W309-I313 HydrophobicContact CZ2-CD1 4Å; W309-I313 PolarHBondContact O-N 3Å; W309-P397 HydrophobicContact CH2-CG 4.23Å; W309-P397 HydrophobicContact CZ3-CG 4.3Å; W309-Q401 HydrophobicContact CH2-CB 3.79Å; W309-Q401 HydrophobicContact CH2-CG 3.87Å; W309-Q401 HydrophobicContact CZ2-CB 4.23Å; W309-Q401 HydrophobicContact CZ2-CG 4.17Å; W309-Q401 HydrophobicContact CZ3-CG 4.49Å; W309-D404 PolarHBondContact NE1-OD2 3.04Å; W309-Y504 VanDerWaalsContact CE2-OH 3.3Å; W309-Y504 WeakPolarHBondContact CZ2-OH 3.12Å; W309-Y504 AromaticContact NE1-CE2 3.85Å; W309-Y504 AromaticContact NE1-CZ 3.74Å; W309-Y504 PolarHBondContact NE1-OH 3.07Å
310L98.1Very high97.5Very high45 Ų4541.2 Ų41.224%0.23622%0.216CC..Hα-helixtrans-62.1-31.9178.8-59.4-178.5000112.4M304 G308 I313 R314 I497 T498M304-L310 HydrophobicContact CE-CD1 4.03Å; M304-L310 HydrophobicContact CE-CG 4.21Å; G308-L310 PolarHBondContact O-N 3.39Å; L310-I313 PolarHBondContact O-N 3.45Å; L310-R314 WeakPolarHBondContact O-CB 3.49Å; L310-R314 PolarHBondContact O-N 2.84Å; L310-I497 HydrophobicContact CB-CG2 4.15Å; L310-I497 HydrophobicContact CD2-CG2 4.39Å; L310-T498 WeakPolarHBondContact CD2-O 3.37Å
311K98.1Very high97.8Very high148 Ų14839.2 Ų39.264%0.64321%0.209SC*.Hα-helixtrans-63.9-41.9172.7177.3-176.4175.8-177.30110.9G308 W309 R314 S315G308-K311 WeakPolarHBondContact O-CB 3.1Å; G308-K311 PolarHBondContact O-N 3.06Å; G308-K311 VanDerWaalsContact O-N 3.15Å; W309-K311 PolarHBondContact O-N 3.02Å; K311-R314 PolarHBondContact O-N 3.4Å; K311-S315 PolarHBondContact O-N 3.24Å; K311-S315 PolarHBondContact O-OG 3.2Å
312H98.5Very high98Very high25 Ų2537.3 Ų37.312%0.11620%0.197CC..Hα-helixtrans-68.1-39.2177.1-59.9-33.8000112.5E273 S281 G308 W309 S315 L316E273-H312 WeakPolarHBondContact CG-CE1 3.44Å; S281-H312 PolarHBondContact OG-CD2 3.12Å; S281-H312 VanDerWaalsContact OG-CD2 3.24Å; G308-H312 PolarHBondContact O-CD2 3.35Å; G308-H312 PolarHBondContact O-N 3.33Å; W309-H312 WeakPolarHBondContact O-CA 3.42Å; W309-H312 WeakPolarHBondContact O-CB 3.33Å; W309-H312 PolarHBondContact O-N 2.87Å; H312-S315 PolarHBondContact O-N 3.43Å; H312-L316 PolarHBondContact O-N 3.33Å; H312-L316 VanDerWaalsContact O-N 3.16Å
313I98.7Very high98.2Very high0 Ų033.5 Ų33.50%017%0.174CC..Hα-helixtrans-58.8-48.4172.2-60.3-56.5000110.5W309 L310 S315 L316 L317 Q401 D404 A405 Q408 I497W309-I313 HydrophobicContact CZ2-CD1 4Å; W309-I313 PolarHBondContact O-N 3Å; L310-I313 PolarHBondContact O-N 3.45Å; I313-S315 VanDerWaalsContact C-N 3.34Å; I313-S315 PolarHBondContact O-N 3.37Å; I313-L316 WeakPolarHBondContact O-CB 3.33Å; I313-L316 PolarHBondContact O-N 3.18Å; I313-L316 VanDerWaalsContact O-N 3.16Å; I313-L317 HydrophobicContact CG2-CD1 4.39Å; I313-L317 PolarHBondContact O-N 3.47Å; I313-Q401 HydrophobicContact CD1-CG 3.56Å; I313-D404 HydrophobicContact CD1-CB 3.73Å; I313-A405 HydrophobicContact CG2-CB 4.36Å; I313-Q408 HydrophobicContact CG2-CG 3.57Å; I313-I497 HydrophobicContact CB-CG2 4.35Å; I313-I497 HydrophobicContact CG2-CG2 4.22Å
314R98.5Very high98.3Very high70 Ų7033.1 Ų33.126%0.26417%0.169SC..Hα-helixtrans-57.4-44.2175.2-171.8-175.8166.1-74.9-7.8112.1L310 K311 L316 L317 E318 L492 I497L310-R314 WeakPolarHBondContact O-CB 3.49Å; L310-R314 PolarHBondContact O-N 2.84Å; K311-R314 PolarHBondContact O-N 3.4Å; R314-L316 VanDerWaalsContact C-N 3.28Å; R314-L316 PolarHBondContact O-N 3.31Å; R314-L317 PolarHBondContact O-N 2.9Å; R314-E318 IonicContact CZ-OE1 2.69Å; R314-E318 IonicContact CZ-OE2 2.84Å; R314-E318 IonicContact NH1-OE1 2.66Å; R314-E318 PolarHBondContact NH1-OE1 3.32Å; R314-E318 IonicContact NH1-OE2 3.37Å; R314-E318 PolarHBondContact NH1-OE2 3.39Å; R314-E318 IonicContact NH2-OE1 3.33Å; R314-E318 PolarHBondContact NH2-OE1 3.4Å; R314-E318 IonicContact NH2-OE2 3.22Å; R314-E318 VanDerWaalsContact O-CB 3.29Å; R314-E318 WeakPolarHBondContact O-CB 3.34Å; R314-E318 PolarHBondContact O-N 2.89Å; R314-L492 PolarHBondContact NE-O 3.44Å; R314-I497 HydrophobicContact CB-CG1 4.11Å; R314-I497 HydrophobicContact CG-CG1 4.18Å
315S98.6Very high98.4Very high7 Ų737 Ų375%0.04919%0.187CC..Hα-helixtrans-59-37178-68.10000112.9A271 K311 H312 I313 T319A271-S315 PolarHBondContact O-OG 3.3Å; K311-S315 PolarHBondContact O-N 3.24Å; K311-S315 PolarHBondContact O-OG 3.2Å; H312-S315 PolarHBondContact O-N 3.43Å; I313-S315 VanDerWaalsContact C-N 3.34Å; I313-S315 PolarHBondContact O-N 3.37Å; S315-T319 WeakPolarHBondContact O-CB 3.08Å; S315-T319 PolarHBondContact O-N 3.29Å; S315-T319 PolarHBondContact O-OG1 3.04Å
316L98.8Very high98.5Very high0 Ų032 Ų320%016%0.158CC..Hα-helixtrans-64.2-49175.1-72.5-179.5000111.4V272 H312 I313 R314 T319 A320 Q346 T347 L350 Q401 A405V272-L316 HydrophobicContact CB-CD2 4.42Å; V272-L316 HydrophobicContact CG1-CD2 3.38Å; V272-L316 HydrophobicContact CG1-CG 4.31Å; V272-L316 HydrophobicContact CG2-CD2 4.11Å; H312-L316 PolarHBondContact O-N 3.33Å; H312-L316 VanDerWaalsContact O-N 3.16Å; I313-L316 WeakPolarHBondContact O-CB 3.33Å; I313-L316 PolarHBondContact O-N 3.18Å; I313-L316 VanDerWaalsContact O-N 3.16Å; R314-L316 VanDerWaalsContact C-N 3.28Å; R314-L316 PolarHBondContact O-N 3.31Å; L316-T319 PolarHBondContact O-N 3.18Å; L316-A320 WeakPolarHBondContact O-CB 3.49Å; L316-A320 PolarHBondContact O-N 3.37Å; L316-Q346 HydrophobicContact CD2-CB 3.88Å; L316-T347 HydrophobicContact CD2-CG2 4.04Å; L316-L350 HydrophobicContact CB-CD1 3.88Å; L316-Q401 HydrophobicContact CD1-CG 3.72Å; L316-A405 HydrophobicContact CB-CB 4.47Å; L316-A405 HydrophobicContact CD1-CB 4.31Å
317L98.8Very high98.6Very high0 Ų027 Ų270%013%0.131CC..Hα-helixtrans-64.7-39.1179.6-66.5173.7000112.2I313 R314 A320 S321 L350 A405 Q408 L409 L492 I497I313-L317 HydrophobicContact CG2-CD1 4.39Å; I313-L317 PolarHBondContact O-N 3.47Å; R314-L317 PolarHBondContact O-N 2.9Å; L317-A320 PolarHBondContact O-N 3.38Å; L317-S321 WeakPolarHBondContact O-CB 3.4Å; L317-S321 PolarHBondContact O-N 3.04Å; L317-L350 HydrophobicContact CD2-CD2 4.34Å; L317-A405 HydrophobicContact CD2-CB 4.14Å; L317-A405 HydrophobicContact CG-CB 4.34Å; L317-Q408 HydrophobicContact CD1-CB 3.84Å; L317-Q408 HydrophobicContact CD1-CG 4.11Å; L317-L409 HydrophobicContact CD2-CD1 4.38Å; L317-L409 HydrophobicContact CD2-CD2 3.93Å; L317-L409 HydrophobicContact CD2-CG 4.01Å; L317-L492 HydrophobicContact CB-CD2 3.59Å; L317-I497 HydrophobicContact CD1-CD1 3.88Å
318E98.7Very high98.6Very high67 Ų6728.3 Ų28.331%0.31314%0.14SC..Hα-helixtrans-62.5-45.4175.7-176.9166.8-124.900111.5R314 S321 F322 L492R314-E318 IonicContact CZ-OE1 2.69Å; R314-E318 IonicContact CZ-OE2 2.84Å; R314-E318 IonicContact NH1-OE1 2.66Å; R314-E318 PolarHBondContact NH1-OE1 3.32Å; R314-E318 IonicContact NH1-OE2 3.37Å; R314-E318 PolarHBondContact NH1-OE2 3.39Å; R314-E318 IonicContact NH2-OE1 3.33Å; R314-E318 PolarHBondContact NH2-OE1 3.4Å; R314-E318 IonicContact NH2-OE2 3.22Å; R314-E318 VanDerWaalsContact O-CB 3.29Å; R314-E318 WeakPolarHBondContact O-CB 3.34Å; R314-E318 PolarHBondContact O-N 2.89Å; E318-S321 PolarHBondContact O-N 3.37Å; E318-F322 PolarHBondContact O-N 3.01Å; E318-L492 HydrophobicContact CB-CD1 4.01Å; E318-L492 HydrophobicContact CG-CD1 4.26Å
319T98.9Very high98.6Very high0 Ų031.9 Ų31.90%016%0.163CC..Hα-helixtrans-64.4-45.5176.6-50.80000111.5V238 T240 F270 V272 S315 L316 F322 I323 T347V238-T319 HydrophobicContact CG1-CG2 4.07Å; T240-T319 HydrophobicContact CG2-CG2 4.18Å; F270-T319 HydrophobicContact CB-CG2 3.99Å; F270-T319 VanDerWaalsContact CB-OG1 3.28Å; F270-T319 WeakPolarHBondContact CB-OG1 3.37Å; F270-T319 HydrophobicContact CD1-CG2 4.04Å; F270-T319 VanDerWaalsContact CD1-OG1 3.31Å; F270-T319 WeakPolarHBondContact CD1-OG1 3.08Å; F270-T319 HydrophobicContact CD2-CG2 3.86Å; F270-T319 HydrophobicContact CE2-CG2 4.41Å; F270-T319 HydrophobicContact CG-CG2 3.67Å; F270-T319 WeakPolarHBondContact CG-OG1 3.44Å; V272-T319 WeakPolarHBondContact CG2-OG1 3.46Å; S315-T319 WeakPolarHBondContact O-CB 3.08Å; S315-T319 PolarHBondContact O-N 3.29Å; S315-T319 PolarHBondContact O-OG1 3.04Å; L316-T319 PolarHBondContact O-N 3.18Å; T319-F322 PolarHBondContact O-N 3.43Å; T319-I323 HydrophobicContact CG2-CD1 4.04Å; T319-I323 WeakPolarHBondContact O-CD1 3.24Å; T319-I323 VanDerWaalsContact O-CG1 3.3Å; T319-I323 WeakPolarHBondContact O-CG1 3.3Å; T319-I323 PolarHBondContact O-N 2.82Å; T319-T347 HydrophobicContact CG2-CG2 3.65Å
320A98.9Very high98.5Very high0 Ų032.6 Ų32.60%017%0.17CC..Hα-helixtrans-64.6-40.8178.600000112.6L316 L317 I323 S324 L350 A351 L354L316-A320 WeakPolarHBondContact O-CB 3.49Å; L316-A320 PolarHBondContact O-N 3.37Å; L317-A320 PolarHBondContact O-N 3.38Å; A320-I323 PolarHBondContact O-N 2.73Å; A320-S324 WeakPolarHBondContact O-CB 3.48Å; A320-S324 PolarHBondContact O-N 2.82Å; A320-L350 HydrophobicContact CB-CB 3.37Å; A320-L350 HydrophobicContact CB-CD1 4.39Å; A320-A351 HydrophobicContact CB-CB 4.45Å; A320-L354 HydrophobicContact CB-CD1 4.25Å
321S98.8Very high98.5Very high20 Ų2031.6 Ų31.614%0.1417%0.166CC..Hα-helixtrans-62.6-42.7176.2-171.30000111.1L317 E318 S324 E325L317-S321 WeakPolarHBondContact O-CB 3.4Å; L317-S321 PolarHBondContact O-N 3.04Å; E318-S321 PolarHBondContact O-N 3.37Å; S321-S324 PolarHBondContact O-N 2.92Å; S321-E325 WeakPolarHBondContact O-CB 3.37Å; S321-E325 PolarHBondContact O-N 3.49Å
322F98.8Very high98.6Very high51 Ų5124.7 Ų24.722%0.22414%0.136CC..Hα-helixtrans-61.8-46.6174.9175.3-93000112.3F236 V238 H268 F270 E318 T319 S324 E325 A326F236-F322 HydrophobicContact CD2-CE1 4.1Å; F236-F322 AromaticContact CD2-CZ 3.87Å; F236-F322 HydrophobicContact CD2-CZ 3.87Å; F236-F322 AromaticContact CE2-CZ 3.98Å; F236-F322 HydrophobicContact CE2-CZ 3.98Å; V238-F322 HydrophobicContact CG2-CD1 4.09Å; V238-F322 HydrophobicContact CG2-CE1 3.78Å; H268-F322 HydrophobicContact CB-CE1 4.12Å; H268-F322 HydrophobicContact CB-CZ 4.2Å; H268-F322 AromaticContact CD2-CZ 3.75Å; H268-F322 AromaticContact CE1-CZ 3.65Å; H268-F322 AromaticContact CG-CE1 3.9Å; H268-F322 AromaticContact CG-CZ 3.55Å; H268-F322 AromaticContact ND1-CZ 3.48Å; H268-F322 WeakPolarHBondContact ND1-CZ 3.23Å; H268-F322 AromaticContact NE2-CZ 3.82Å; F270-F322 HydrophobicContact CE1-CB 3.93Å; F270-F322 HydrophobicContact CE1-CG 4.18Å; F270-F322 AromaticContact CE2-CD1 3.7Å; F270-F322 HydrophobicContact CE2-CD1 3.7Å; F270-F322 HydrophobicContact CE2-CE1 4.1Å; F270-F322 HydrophobicContact CE2-CG 4.14Å; F270-F322 HydrophobicContact CZ-CB 3.56Å; F270-F322 AromaticContact CZ-CD1 3.41Å; F270-F322 HydrophobicContact CZ-CD1 3.41Å; F270-F322 VanDerWaalsContact CZ-CD1 3.41Å; F270-F322 AromaticContact CZ-CD2 3.95Å; F270-F322 HydrophobicContact CZ-CD2 3.95Å; F270-F322 HydrophobicContact CZ-CE1 4.06Å; F270-F322 AromaticContact CZ-CG 3.35Å; F270-F322 HydrophobicContact CZ-CG 3.35Å; E318-F322 PolarHBondContact O-N 3.01Å; T319-F322 PolarHBondContact O-N 3.43Å; F322-S324 VanDerWaalsContact C-N 3.34Å; F322-S324 PolarHBondContact O-N 3.34Å; F322-E325 PolarHBondContact O-N 3.41Å; F322-A326 WeakPolarHBondContact O-CB 3.45Å; F322-A326 PolarHBondContact O-N 3.14Å
323I98.9Very high98.6Very high0 Ų023.5 Ų23.50%013%0.131CC..Hα-helixtrans-60.5-46.4177.7-65160.3000110.1I201 V238 T319 A320 E325 A326 V327 V333 V335 A351I201-I323 HydrophobicContact CD1-CG2 3.72Å; I201-I323 HydrophobicContact CG1-CG2 3.98Å; I201-I323 HydrophobicContact CG2-CG2 4.49Å; V238-I323 HydrophobicContact CG1-CD1 4.24Å; V238-I323 HydrophobicContact CG1-CG1 4.29Å; V238-I323 HydrophobicContact CG2-CG1 4.25Å; T319-I323 HydrophobicContact CG2-CD1 4.04Å; T319-I323 WeakPolarHBondContact O-CD1 3.24Å; T319-I323 VanDerWaalsContact O-CG1 3.3Å; T319-I323 WeakPolarHBondContact O-CG1 3.3Å; T319-I323 PolarHBondContact O-N 2.82Å; A320-I323 PolarHBondContact O-N 2.73Å; I323-E325 PolarHBondContact O-N 3.28Å; I323-A326 PolarHBondContact O-N 2.88Å; I323-V327 HydrophobicContact CG2-CG2 4.46Å; I323-V327 WeakPolarHBondContact O-CB 3.36Å; I323-V327 VanDerWaalsContact O-CG2 3.3Å; I323-V327 WeakPolarHBondContact O-CG2 3.44Å; I323-V327 PolarHBondContact O-N 3.38Å; I323-V333 HydrophobicContact CG1-CG1 4.38Å; I323-V333 HydrophobicContact CG2-CB 4.44Å; I323-V333 HydrophobicContact CG2-CG1 4.36Å; I323-V333 HydrophobicContact CG2-CG2 4.48Å; I323-V335 HydrophobicContact CD1-CG1 4.23Å; I323-V335 HydrophobicContact CD1-CG2 3.74Å; I323-V335 HydrophobicContact CG1-CG2 4.21Å; I323-V335 HydrophobicContact CG2-CG2 4.5Å; I323-A351 HydrophobicContact CB-CB 3.88Å; I323-A351 HydrophobicContact CG2-CB 3.67Å
324S98.8Very high98.6Very high7 Ų723.5 Ų23.55%0.04913%0.131CC..Hα-helixtrans-59.3-45.5177.11770000112.1A320 S321 F322 V327 S328 L355A320-S324 WeakPolarHBondContact O-CB 3.48Å; A320-S324 PolarHBondContact O-N 2.82Å; S321-S324 PolarHBondContact O-N 2.92Å; F322-S324 VanDerWaalsContact C-N 3.34Å; F322-S324 PolarHBondContact O-N 3.34Å; S324-V327 PolarHBondContact O-N 2.82Å; S324-S328 VanDerWaalsContact O-CB 3.32Å; S324-S328 WeakPolarHBondContact O-CB 3.33Å; S324-S328 PolarHBondContact O-N 2.8Å; S324-S328 PolarHBondContact O-OG 3.35Å; S324-L355 WeakPolarHBondContact O-CD2 3Å; S324-L355 WeakPolarHBondContact OG-CG 3.25Å
325E98.5Very high98.6Very high99 Ų9920.2 Ų20.246%0.46312%0.118SC..Hα-helixtrans-65.9-41.8179.1-175.1160.2-137.900112.2S321 F322 I323 S328 S329S321-E325 WeakPolarHBondContact O-CB 3.37Å; S321-E325 PolarHBondContact O-N 3.49Å; F322-E325 PolarHBondContact O-N 3.41Å; I323-E325 PolarHBondContact O-N 3.28Å; E325-S328 WeakPolarHBondContact CA-OG 3.5Å; E325-S328 PolarHBondContact O-OG 3.26Å; E325-S329 WeakPolarHBondContact O-CB 3.31Å; E325-S329 PolarHBondContact O-N 3.47Å; E325-S329 PolarHBondContact O-OG 2.99Å
326A98.5Very high98.6Very high9 Ų919.9 Ų19.97%0.07412%0.116CC..Hα-helixtrans-60.8-48.7175.500000111.7F236 F322 I323 S329 G330 T331 V333F236-A326 HydrophobicContact CD2-CB 3.83Å; F236-A326 HydrophobicContact CE2-CB 4.06Å; F322-A326 WeakPolarHBondContact O-CB 3.45Å; F322-A326 PolarHBondContact O-N 3.14Å; I323-A326 PolarHBondContact O-N 2.88Å; A326-S329 CarbonylContact O-C 3.29Å; A326-S329 PolarHBondContact O-N 3.35Å; A326-G330 PolarHBondContact O-N 3.23Å; A326-T331 CarbonylContact C-O 3.5Å; A326-T331 WeakPolarHBondContact O-CA 3.46Å; A326-T331 WeakPolarHBondContact O-CB 3.38Å; A326-T331 PolarHBondContact O-N 3.2Å; A326-V333 HydrophobicContact CB-CG2 3.84Å
327V98.7Very high98.5Very high0 Ų020 Ų200%012%0.117CC..Hα-helixtrans-66.5-47-178.8171.30000111.7Y194 N197 A199 I201 I323 S324 S329 G330 T331 V333 L355Y194-V327 HydrophobicContact CD1-CG1 4.47Å; Y194-V327 HydrophobicContact CG-CG1 4.03Å; N197-V327 PolarHBondContact ND2-O 2.82Å; A199-V327 HydrophobicContact CB-CG1 3.99Å; A199-V327 WeakPolarHBondContact CB-O 3.48Å; I201-V327 HydrophobicContact CD1-CG2 4.31Å; I201-V327 HydrophobicContact CG1-CG2 3.68Å; I323-V327 HydrophobicContact CG2-CG2 4.46Å; I323-V327 WeakPolarHBondContact O-CB 3.36Å; I323-V327 VanDerWaalsContact O-CG2 3.3Å; I323-V327 WeakPolarHBondContact O-CG2 3.44Å; I323-V327 PolarHBondContact O-N 3.38Å; S324-V327 PolarHBondContact O-N 2.82Å; V327-S329 PolarHBondContact O-N 3.06Å; V327-G330 PolarHBondContact O-N 3.25Å; V327-T331 WeakPolarHBondContact CA-O 3.3Å; V327-T331 PolarHBondContact N-O 3.02Å; V327-V333 HydrophobicContact CG2-CB 4.46Å; V327-V333 HydrophobicContact CG2-CG2 3.82Å; V327-L355 HydrophobicContact CB-CD1 4.05Å; V327-L355 HydrophobicContact CB-CD2 4.27Å; V327-L355 HydrophobicContact CG1-CD1 3.88Å; V327-L355 HydrophobicContact CG1-CD2 4.1Å
328S98.1Very high98.4Very high32 Ų3220.8 Ų20.822%0.22412%0.123CC..Hα-helixtrans-63.9-28.1177.356.90000112.5N197 S324 E325 G330N197-S328 PolarHBondContact ND2-O 2.9Å; N197-S328 VanDerWaalsContact ND2-O 3.16Å; S324-S328 VanDerWaalsContact O-CB 3.32Å; S324-S328 WeakPolarHBondContact O-CB 3.33Å; S324-S328 PolarHBondContact O-N 2.8Å; S324-S328 PolarHBondContact O-OG 3.35Å; E325-S328 WeakPolarHBondContact CA-OG 3.5Å; E325-S328 PolarHBondContact O-OG 3.26Å; S328-G330 VanDerWaalsContact C-N 3.27Å; S328-G330 PolarHBondContact O-N 3.43Å
329S97.4Very high98.3Very high90 Ų9018.9 Ų18.963%0.62912%0.115SC*.THydrogen-bonded Turntrans-82.53.5172.7-54.50000114.2E325 A326 V327E325-S329 WeakPolarHBondContact O-CB 3.31Å; E325-S329 PolarHBondContact O-N 3.47Å; E325-S329 PolarHBondContact O-OG 2.99Å; A326-S329 CarbonylContact O-C 3.29Å; A326-S329 PolarHBondContact O-N 3.35Å; V327-S329 PolarHBondContact O-N 3.06Å
330G97.9Very high98.2Very high14 Ų1418.9 Ų18.914%0.14412%0.115CC..THydrogen-bonded Turntrans93.811173.700000115.4N197 N229 S232 A326 V327 S328N197-G330 VanDerWaalsContact ND2-CA 3.3Å; N197-G330 WeakPolarHBondContact ND2-CA 3.48Å; N197-G330 PolarHBondContact ND2-N 3.21Å; N229-G330 PolarHBondContact ND2-O 3.36Å; S232-G330 WeakPolarHBondContact CB-O 3.5Å; A326-G330 PolarHBondContact O-N 3.23Å; V327-G330 PolarHBondContact O-N 3.25Å; S328-G330 VanDerWaalsContact C-N 3.27Å; S328-G330 PolarHBondContact O-N 3.43Å
331T98.4Very high98.1Very high25 Ų2519.8 Ų19.815%0.15312%0.118CC..  trans-101.8123.5178.1-60.60000111F236 A326 V327F236-T331 HydrophobicContact CB-CG2 4.3Å; F236-T331 HydrophobicContact CD1-CG2 3.68Å; F236-T331 HydrophobicContact CD2-CG2 3.81Å; F236-T331 HydrophobicContact CE1-CG2 3.89Å; F236-T331 HydrophobicContact CE2-CG2 4Å; F236-T331 HydrophobicContact CG-CG2 3.65Å; F236-T331 HydrophobicContact CZ-CG2 4.04Å; A326-T331 CarbonylContact C-O 3.5Å; A326-T331 WeakPolarHBondContact O-CA 3.46Å; A326-T331 WeakPolarHBondContact O-CB 3.38Å; A326-T331 PolarHBondContact O-N 3.2Å; V327-T331 WeakPolarHBondContact CA-O 3.3Å; V327-T331 PolarHBondContact N-O 3.02Å
332S98.7Very high98.1Very high3 Ų319.4 Ų19.42%0.02111%0.114CC..  trans-71.4148.5173-62.40000111.5V200 N229 L235 F236V200-S332 PolarHBondContact N-OG 3.29Å; V200-S332 CarbonylContact O-C 2.76Å; V200-S332 WeakPolarHBondContact O-CA 3.33Å; N229-S332 VanDerWaalsContact CB-OG 3.27Å; N229-S332 WeakPolarHBondContact CB-OG 3.27Å; N229-S332 PolarHBondContact ND2-OG 3.05Å; N229-S332 VanDerWaalsContact ND2-OG 3.16Å; L235-S332 WeakPolarHBondContact CD1-O 3.45Å; F236-S332 PolarHBondContact N-O 3.21Å
333V98.8Very high98.1Very high0 Ų017.7 Ų17.70%011%0.106CC..EExtended strand (participates in β ladder)trans-131.3135.4-174.2-172.50000110.7V200 I201 C202 F236 V238 I323 A326 V327 V335V200-V333 PolarHBondContact O-N 3.08Å; I201-V333 CarbonylContact C-O 3.49Å; I201-V333 WeakPolarHBondContact CA-O 3.16Å; C202-V333 PolarHBondContact N-O 2.98Å; F236-V333 HydrophobicContact CB-CG1 4.41Å; F236-V333 HydrophobicContact CB-CG2 4.25Å; F236-V333 CarbonylContact O-C 3.57Å; F236-V333 VanDerWaalsContact O-CA 3.31Å; F236-V333 WeakPolarHBondContact O-CA 3.38Å; V238-V333 HydrophobicContact CB-CG1 4.09Å; V238-V333 HydrophobicContact CG2-CG1 3.53Å; I323-V333 HydrophobicContact CG1-CG1 4.38Å; I323-V333 HydrophobicContact CG2-CB 4.44Å; I323-V333 HydrophobicContact CG2-CG1 4.36Å; I323-V333 HydrophobicContact CG2-CG2 4.48Å; A326-V333 HydrophobicContact CB-CG2 3.84Å; V327-V333 HydrophobicContact CG2-CB 4.46Å; V327-V333 HydrophobicContact CG2-CG2 3.82Å; V333-V335 HydrophobicContact CG1-CG2 3.82Å
334V98.8Very high98.1Very high0 Ų017.7 Ų17.70%011%0.106CC..EExtended strand (participates in β ladder)trans-109.1121.4166.7179.90000108.5C202 C204 M222 I225 L235 F236 I237 V238C202-V334 HydrophobicContact CB-CB 4.42Å; C202-V334 HydrophobicContact CB-CG1 4.41Å; C202-V334 HydrophobicContact CB-CG2 3.94Å; C202-V334 CarbonylContact O-C 3.46Å; C202-V334 WeakPolarHBondContact O-CA 3.41Å; C204-V334 WeakPolarHBondContact SG-CG1 3.21Å; M222-V334 HydrophobicContact CE-CG1 4.08Å; M222-V334 HydrophobicContact SD-CG1 4.42Å; M222-V334 HydrophobicContact SD-CG2 3.9Å; I225-V334 HydrophobicContact CD1-CG2 4.32Å; I225-V334 HydrophobicContact CG2-CG2 4.27Å; L235-V334 HydrophobicContact CD1-CG2 4.17Å; L235-V334 HydrophobicContact CD2-CG2 4.04Å; L235-V334 HydrophobicContact CG-CG2 4.37Å; F236-V334 PolarHBondContact O-N 3.21Å; I237-V334 CarbonylContact C-O 3.36Å; I237-V334 WeakPolarHBondContact CA-O 3.38Å; I237-V334 HydrophobicContact CG1-CB 4.4Å; V238-V334 PolarHBondContact N-O 3.29Å
335V98.9Very high98.1Very high0 Ų017.3 Ų17.30%010%0.104CC..EExtended strand (participates in β ladder)trans-109.4129.9-175.3-172.30000110.2I201 C202 R203 C204 V238 T240 I323 V333 T344 V348I201-V335 HydrophobicContact CG2-CG2 3.95Å; C202-V335 PolarHBondContact O-N 3.12Å; R203-V335 WeakPolarHBondContact CA-O 3.45Å; C204-V335 PolarHBondContact N-O 3.41Å; V238-V335 HydrophobicContact CB-CG2 4.32Å; V238-V335 HydrophobicContact CG1-CG1 4.37Å; V238-V335 WeakPolarHBondContact O-CA 3.35Å; T240-V335 HydrophobicContact CG2-CG1 3.79Å; I323-V335 HydrophobicContact CD1-CG1 4.23Å; I323-V335 HydrophobicContact CD1-CG2 3.74Å; I323-V335 HydrophobicContact CG1-CG2 4.21Å; I323-V335 HydrophobicContact CG2-CG2 4.5Å; V333-V335 HydrophobicContact CG1-CG2 3.82Å; V335-T344 HydrophobicContact CG1-CG2 4.39Å; V335-V348 HydrophobicContact CB-CG2 3.92Å; V335-V348 HydrophobicContact CG1-CG2 4.12Å; V335-V348 HydrophobicContact CG2-CG2 4.13Å
336H98.5Very high98.1Very high0 Ų012.6 Ų12.60%08%0.082CC..EExtended strand (participates in β ladder)trans-142171.7170.268.389000112.9C204 V238 D239 T240 E257 Y267 T344C204-H336 WeakPolarHBondContact O-CA 3.44Å; C204-H336 WeakPolarHBondContact O-CB 3.27Å; V238-H336 PolarHBondContact O-N 3.32Å; D239-H336 IonicContact OD2-CE1 3.41Å; D239-H336 PolarHBondContact OD2-CE1 3.03Å; T240-H336 WeakPolarHBondContact CG2-O 3.4Å; T240-H336 PolarHBondContact N-O 3.13Å; T240-H336 PolarHBondContact OG1-O 3.12Å; E257-H336 IonicContact OE1-NE2 3.13Å; E257-H336 IonicContact OE2-CE1 3.12Å; E257-H336 IonicContact OE2-NE2 3.91Å; E257-H336 PolarHBondContact OE2-NE2 3.3Å; Y267-H336 AromaticContact CZ-NE2 3.88Å; Y267-H336 PolarHBondContact OH-CE1 3Å; Y267-H336 PolarHBondContact OH-NE2 3.45Å; H336-T344 WeakPolarHBondContact CA-OG1 3.41Å
337C97.4Very high98.1Very high2 Ų212.2 Ų12.21%0.0148%0.078CC..  trans-131.2-131.6171.2700000109.4Q206 T240 R241 G340 R343 T344Q206-C337 WeakPolarHBondContact CB-O 3.5Å; T240-C337 WeakPolarHBondContact OG1-CA 3.35Å; T240-C337 WeakPolarHBondContact OG1-CB 3.4Å; R241-C337 HydrophobicContact CG-CB 4.45Å; C337-G340 VanDerWaalsContact SG-CA 3.55Å; C337-G340 PolarHBondContact SG-N 2.94Å; C337-R343 HydrophobicContact CB-CB 3.77Å; C337-T344 PolarHBondContact N-OG1 3.05Å; C337-T344 PolarHBondContact SG-OG1 2.89Å; C337-T344 VanDerWaalsContact SG-OG1 3.35Å
338S97Very high98.2Very high18 Ų1812.2 Ų12.213%0.1268%0.078CC..SBendtrans-77.1-73.9168.9-63.70000110.5Q206 R241 R343Q206-S338 WeakPolarHBondContact CB-O 3.46Å; Q206-S338 WeakPolarHBondContact CG-O 3.5Å; Q206-S338 PolarHBondContact N-O 3.49Å; Q206-S338 VanDerWaalsContact NE2-CA 3.35Å; Q206-S338 PolarHBondContact NE2-O 2.82Å; Q206-S338 VanDerWaalsContact NE2-O 3.14Å; R241-S338 WeakPolarHBondContact CD-OG 3.35Å; S338-R343 PolarHBondContact OG-NH2 2.81Å
339D96Very high98.2Very high27 Ų2710.7 Ų10.714%0.1447%0.068CC..SBendtrans-102.3-0.2-178.3-62.5-68.6000112.8S183 R184 R186 S205 K254 W341S183-D339 PolarHBondContact OG-OD1 2.81Å; R184-D339 IonicContact NE-OD1 2.72Å; R186-D339 WeakPolarHBondContact CD-O 3.38Å; R186-D339 PolarHBondContact NE-O 3.48Å; S205-D339 WeakPolarHBondContact CB-O 3.4Å; K254-D339 IonicContact NZ-OD1 3.4Å; D339-W341 HydrophobicContact CB-CD2 3.65Å; D339-W341 VanDerWaalsContact CB-CE2 3.46Å; D339-W341 HydrophobicContact CB-CE3 3.76Å; D339-W341 HydrophobicContact CB-CH2 3.68Å; D339-W341 HydrophobicContact CB-CZ2 3.46Å; D339-W341 VanDerWaalsContact CB-CZ2 3.46Å; D339-W341 HydrophobicContact CB-CZ3 3.8Å; D339-W341 PolarHBondContact O-N 3.01Å
340G96.8Very high98.3Very high0 Ų06.4 Ų6.40%04%0.038CC..SBendtrans78.714.4170.600000116R186 R203 C204 C337 T344R186-G340 PolarHBondContact NH2-O 3.13Å; R203-G340 PolarHBondContact NH2-O 2.89Å; C204-G340 WeakPolarHBondContact O-CA 3.49Å; C337-G340 VanDerWaalsContact SG-CA 3.55Å; C337-G340 PolarHBondContact SG-N 2.94Å; G340-T344 WeakPolarHBondContact CA-OG1 3.38Å
341W97.3Very high98.3Very high19 Ų195.7 Ų5.77%0.0723%0.031CC..SBendtrans-122.5-6.9-178.357.859.2000115.1R184 D339 P345 G377 H378 K379R184-W341 VanDerWaalsContact CZ-CH2 3.49Å; D339-W341 HydrophobicContact CB-CD2 3.65Å; D339-W341 VanDerWaalsContact CB-CE2 3.46Å; D339-W341 HydrophobicContact CB-CE3 3.76Å; D339-W341 HydrophobicContact CB-CH2 3.68Å; D339-W341 HydrophobicContact CB-CZ2 3.46Å; D339-W341 VanDerWaalsContact CB-CZ2 3.46Å; D339-W341 HydrophobicContact CB-CZ3 3.8Å; D339-W341 PolarHBondContact O-N 3.01Å; W341-P345 WeakPolarHBondContact O-CG 3.45Å; W341-G377 WeakPolarHBondContact CB-O 3.32Å; W341-H378 PolarHBondContact O-ND1 3.4Å; W341-K379 HydrophobicContact CD2-CD 4.46Å; W341-K379 HydrophobicContact CH2-CD 4.24Å; W341-K379 HydrophobicContact CZ2-CD 3.95Å
342D98.4Very high98.3Very high12 Ų124.5 Ų4.56%0.0642%0.024CC..SBendtrans-107-77.9177.2-68.9-47.9000110.7I275 T344 P345 Q346 H378 R383 I398I275-D342 HydrophobicContact CG2-CB 4.4Å; I275-D342 WeakPolarHBondContact CG2-OD2 3.31Å; D342-T344 VanDerWaalsContact C-N 3.34Å; D342-T344 PolarHBondContact O-N 2.89Å; D342-P345 WeakPolarHBondContact O-CD 3.28Å; D342-P345 VanDerWaalsContact O-CG 3.26Å; D342-P345 WeakPolarHBondContact O-CG 3.38Å; D342-Q346 WeakPolarHBondContact O-CG 3.37Å; D342-Q346 PolarHBondContact O-N 2.94Å; D342-H378 IonicContact OD1-CE1 3.93Å; D342-H378 PolarHBondContact OD1-CE1 3.05Å; D342-H378 VanDerWaalsContact OD1-CE1 3.29Å; D342-H378 IonicContact OD1-ND1 3.9Å; D342-R383 IonicContact OD1-CZ 2.82Å; D342-R383 IonicContact OD1-NE 3.57Å; D342-R383 PolarHBondContact OD1-NE 2.95Å; D342-R383 IonicContact OD1-NH2 3.98Å; D342-R383 IonicContact OD2-CZ 3.56Å; D342-R383 IonicContact OD2-NE 3.97Å; D342-R383 PolarHBondContact OD2-NE 3.2Å; D342-R383 IonicContact OD2-NH2 3.54Å; D342-R383 PolarHBondContact OD2-NH2 3.4Å; D342-I398 HydrophobicContact CB-CG2 4.11Å
343R98.7Very high98.4Very high14 Ų144.4 Ų4.45%0.0532%0.023CC..Hα-helixtrans-71.7-28.8-175.9-63.2164.9-81.8-161.1-2.3114.1T240 V272 E273 C337 S338 T347T240-R343 WeakPolarHBondContact OG1-CB 3.17Å; V272-R343 HydrophobicContact CB-CB 4.43Å; V272-R343 HydrophobicContact CB-CG 4.11Å; V272-R343 HydrophobicContact CG1-CB 4.07Å; V272-R343 HydrophobicContact CG1-CG 3.55Å; V272-R343 WeakPolarHBondContact O-CD 3.48Å; V272-R343 PolarHBondContact O-NH1 3.32Å; E273-R343 WeakPolarHBondContact O-CD 3.27Å; C337-R343 HydrophobicContact CB-CB 3.77Å; S338-R343 PolarHBondContact OG-NH2 2.81Å; R343-T347 WeakPolarHBondContact O-CG2 3.34Å; R343-T347 PolarHBondContact O-N 3.23Å; R343-T347 PolarHBondContact O-OG1 3.45Å
344T98.8Very high98.4Very high0 Ų04.4 Ų4.40%02%0.023CC..Hα-helixtrans-63.5-56.7178.5-580000111.3R203 V335 H336 C337 G340 D342 Q346 T347 V348R203-T344 HydrophobicContact CB-CG2 3.76Å; V335-T344 HydrophobicContact CG1-CG2 4.39Å; H336-T344 WeakPolarHBondContact CA-OG1 3.41Å; C337-T344 PolarHBondContact N-OG1 3.05Å; C337-T344 PolarHBondContact SG-OG1 2.89Å; C337-T344 VanDerWaalsContact SG-OG1 3.35Å; G340-T344 WeakPolarHBondContact CA-OG1 3.38Å; D342-T344 VanDerWaalsContact C-N 3.34Å; D342-T344 PolarHBondContact O-N 2.89Å; T344-Q346 VanDerWaalsContact C-N 3.29Å; T344-Q346 PolarHBondContact O-N 3.28Å; T344-T347 PolarHBondContact O-N 3.07Å; T344-T347 PolarHBondContact O-OG1 2.83Å; T344-V348 HydrophobicContact CG2-CG2 4.12Å; T344-V348 WeakPolarHBondContact O-CB 3.28Å; T344-V348 VanDerWaalsContact O-CG2 3.25Å; T344-V348 WeakPolarHBondContact O-CG2 3.5Å; T344-V348 PolarHBondContact O-N 2.72Å
345P98.8Very high98.3Very high0 Ų04.5 Ų4.50%02%0.023CC..Hα-helixtrans-63.2-32.6177.223.9-33.3000113.2W341 D342 S349 E372 W373W341-P345 WeakPolarHBondContact O-CG 3.45Å; D342-P345 WeakPolarHBondContact O-CD 3.28Å; D342-P345 VanDerWaalsContact O-CG 3.26Å; D342-P345 WeakPolarHBondContact O-CG 3.38Å; P345-S349 WeakPolarHBondContact O-CB 3.4Å; P345-S349 PolarHBondContact O-N 2.91Å; P345-S349 PolarHBondContact O-OG 2.89Å; P345-E372 HydrophobicContact CB-CB 4.5Å; P345-E372 WeakPolarHBondContact CB-O 3.29Å; P345-W373 HydrophobicContact CB-CD2 4.04Å; P345-W373 HydrophobicContact CB-CE3 4.32Å; P345-W373 HydrophobicContact CB-CG 4.43Å; P345-W373 HydrophobicContact CB-CZ2 4.36Å; P345-W373 HydrophobicContact CG-CE3 4.32Å; P345-W373 HydrophobicContact CG-CZ3 4.37Å
346Q98.9Very high98.3Very high0 Ų05.4 Ų5.40%03%0.028CC..Hα-helixtrans-56.1-55.7172.8-68.8178-50.300111.8L316 D342 T344 L350 W373 I398 F402L316-Q346 HydrophobicContact CD2-CB 3.88Å; D342-Q346 WeakPolarHBondContact O-CG 3.37Å; D342-Q346 PolarHBondContact O-N 2.94Å; T344-Q346 VanDerWaalsContact C-N 3.29Å; T344-Q346 PolarHBondContact O-N 3.28Å; Q346-L350 WeakPolarHBondContact O-CB 3.34Å; Q346-L350 WeakPolarHBondContact O-CD1 3.43Å; Q346-L350 VanDerWaalsContact O-CG 3.24Å; Q346-L350 WeakPolarHBondContact O-CG 3.41Å; Q346-L350 PolarHBondContact O-N 3.37Å; Q346-L350 VanDerWaalsContact O-N 3.09Å; Q346-W373 HydrophobicContact CB-CH2 4.44Å; Q346-W373 HydrophobicContact CB-CZ2 4.48Å; Q346-W373 HydrophobicContact CG-CH2 3.49Å; Q346-W373 VanDerWaalsContact CG-CH2 3.49Å; Q346-W373 HydrophobicContact CG-CZ2 3.97Å; Q346-I398 HydrophobicContact CG-CG2 4.02Å; Q346-I398 PolarHBondContact NE2-O 2.88Å; Q346-F402 HydrophobicContact CG-CB 4.19Å
347T98.9Very high98.3Very high0 Ų06.5 Ų6.50%04%0.035CC..Hα-helixtrans-74.8-38.4-173.751.90000112.8T240 V272 L316 T319 R343 T344 A351T240-T347 HydrophobicContact CG2-CG2 3.99Å; T240-T347 WeakPolarHBondContact CG2-OG1 3.32Å; V272-T347 HydrophobicContact CG2-CG2 4.28Å; L316-T347 HydrophobicContact CD2-CG2 4.04Å; T319-T347 HydrophobicContact CG2-CG2 3.65Å; R343-T347 WeakPolarHBondContact O-CG2 3.34Å; R343-T347 PolarHBondContact O-N 3.23Å; R343-T347 PolarHBondContact O-OG1 3.45Å; T344-T347 PolarHBondContact O-N 3.07Å; T344-T347 PolarHBondContact O-OG1 2.83Å; T347-A351 WeakPolarHBondContact O-CB 3.46Å; T347-A351 PolarHBondContact O-N 2.89Å
348V98.9Very high98.3Very high0 Ų09 Ų90%05%0.045CC..Hα-helixtrans-63.5-47174.2172.10000110.6I201 V335 T344 L350 A351 C352 E372I201-V348 HydrophobicContact CG2-CG1 4.17Å; I201-V348 HydrophobicContact CG2-CG2 4.03Å; V335-V348 HydrophobicContact CB-CG2 3.92Å; V335-V348 HydrophobicContact CG1-CG2 4.12Å; V335-V348 HydrophobicContact CG2-CG2 4.13Å; T344-V348 HydrophobicContact CG2-CG2 4.12Å; T344-V348 WeakPolarHBondContact O-CB 3.28Å; T344-V348 VanDerWaalsContact O-CG2 3.25Å; T344-V348 WeakPolarHBondContact O-CG2 3.5Å; T344-V348 PolarHBondContact O-N 2.72Å; V348-L350 PolarHBondContact O-N 3.34Å; V348-A351 PolarHBondContact O-N 3.22Å; V348-C352 WeakPolarHBondContact O-CB 3.46Å; V348-C352 PolarHBondContact O-N 3.24Å; V348-C352 PolarHBondContact O-SG 3.46Å; V348-E372 HydrophobicContact CG1-CG 4.28Å; V348-E372 WeakPolarHBondContact CG1-OE2 3.46Å
349S98.9Very high98.4Very high0 Ų08.1 Ų8.10%04%0.039CC..Hα-helixtrans-62.8-44.9179.4-58.90000111.8P345 C352 I353 E372 W373 F402P345-S349 WeakPolarHBondContact O-CB 3.4Å; P345-S349 PolarHBondContact O-N 2.91Å; P345-S349 PolarHBondContact O-OG 2.89Å; S349-C352 WeakPolarHBondContact O-CB 3.49Å; S349-C352 PolarHBondContact O-N 3.39Å; S349-I353 WeakPolarHBondContact O-CG1 3.19Å; S349-I353 PolarHBondContact O-N 2.89Å; S349-E372 WeakPolarHBondContact OG-CB 3.39Å; S349-W373 PolarHBondContact OG-NE1 3.2Å; S349-F402 VanDerWaalsContact CB-CE2 3.5Å
350L99Very high98.5Very high0 Ų06.9 Ų6.90%03%0.032CC..Hα-helixtrans-62.4-43.6176.2-72.2167.6000111.5L316 L317 A320 Q346 V348 C352 I353 L354 F402 A405 V406 L409L316-L350 HydrophobicContact CB-CD1 3.88Å; L317-L350 HydrophobicContact CD2-CD2 4.34Å; A320-L350 HydrophobicContact CB-CB 3.37Å; A320-L350 HydrophobicContact CB-CD1 4.39Å; Q346-L350 WeakPolarHBondContact O-CB 3.34Å; Q346-L350 WeakPolarHBondContact O-CD1 3.43Å; Q346-L350 VanDerWaalsContact O-CG 3.24Å; Q346-L350 WeakPolarHBondContact O-CG 3.41Å; Q346-L350 PolarHBondContact O-N 3.37Å; Q346-L350 VanDerWaalsContact O-N 3.09Å; V348-L350 PolarHBondContact O-N 3.34Å; L350-C352 VanDerWaalsContact C-N 3.33Å; L350-C352 PolarHBondContact O-N 3.06Å; L350-I353 WeakPolarHBondContact O-CB 3.49Å; L350-I353 PolarHBondContact O-N 3.44Å; L350-L354 WeakPolarHBondContact O-CG 3.39Å; L350-L354 PolarHBondContact O-N 3.24Å; L350-F402 HydrophobicContact CD1-CD2 4.5Å; L350-F402 HydrophobicContact CD2-CD2 4.19Å; L350-F402 HydrophobicContact CD2-CE2 4.05Å; L350-F402 HydrophobicContact CG-CD2 3.97Å; L350-F402 HydrophobicContact CG-CE2 3.96Å; L350-A405 HydrophobicContact CD1-CB 3.77Å; L350-A405 HydrophobicContact CD2-CB 3.95Å; L350-A405 HydrophobicContact CG-CB 4.49Å; L350-V406 HydrophobicContact CD2-CG2 3.85Å; L350-L409 HydrophobicContact CD2-CD1 4.14Å
351A98.9Very high98.5Very high0 Ų08.3 Ų8.30%04%0.041CC..Hα-helixtrans-61-42.9176.900000111.7I201 A320 I323 T347 V348 I353 L354 L355I201-A351 HydrophobicContact CD1-CB 4Å; A320-A351 HydrophobicContact CB-CB 4.45Å; I323-A351 HydrophobicContact CB-CB 3.88Å; I323-A351 HydrophobicContact CG2-CB 3.67Å; T347-A351 WeakPolarHBondContact O-CB 3.46Å; T347-A351 PolarHBondContact O-N 2.89Å; V348-A351 PolarHBondContact O-N 3.22Å; A351-I353 PolarHBondContact O-N 2.96Å; A351-L354 PolarHBondContact O-N 3.2Å; A351-L355 WeakPolarHBondContact O-CB 3.18Å; A351-L355 WeakPolarHBondContact O-CD1 3.03Å; A351-L355 VanDerWaalsContact O-CG 3.3Å; A351-L355 WeakPolarHBondContact O-CG 3.42Å; A351-L355 PolarHBondContact O-N 3.16Å
352C98.9Very high98.5Very high0 Ų08.6 Ų8.60%04%0.043CC..Hα-helixtrans-56.4-47.1173.2-73.20000111.9V348 S349 L350 L354 L355 D356 Y359 L368V348-C352 WeakPolarHBondContact O-CB 3.46Å; V348-C352 PolarHBondContact O-N 3.24Å; V348-C352 PolarHBondContact O-SG 3.46Å; S349-C352 WeakPolarHBondContact O-CB 3.49Å; S349-C352 PolarHBondContact O-N 3.39Å; L350-C352 VanDerWaalsContact C-N 3.33Å; L350-C352 PolarHBondContact O-N 3.06Å; C352-L354 VanDerWaalsContact C-N 3.29Å; C352-L354 PolarHBondContact O-N 3.16Å; C352-L355 PolarHBondContact O-N 2.91Å; C352-L355 VanDerWaalsContact O-N 3.12Å; C352-D356 PolarHBondContact O-N 3.05Å; C352-Y359 HydrophobicContact CB-CD2 3.6Å; C352-Y359 HydrophobicContact CB-CE2 3.57Å; C352-Y359 HydrophobicContact CB-CG 4.48Å; C352-Y359 WeakPolarHBondContact O-CD2 3.46Å; C352-L368 HydrophobicContact CB-CD1 3.96Å; C352-L368 HydrophobicContact CB-CD2 4.41Å
353I98.9Very high98.4Very high0 Ų012.1 Ų12.10%06%0.058CC..Hα-helixtrans-59.3-39.5177.2-70163.8000111.9S349 L350 A351 R360 F365 L368 F402 V406 L409 F417S349-I353 WeakPolarHBondContact O-CG1 3.19Å; S349-I353 PolarHBondContact O-N 2.89Å; L350-I353 WeakPolarHBondContact O-CB 3.49Å; L350-I353 PolarHBondContact O-N 3.44Å; A351-I353 PolarHBondContact O-N 2.96Å; I353-R360 HydrophobicContact CG2-CG 4.22Å; I353-R360 PolarHBondContact O-NE 3.49Å; I353-R360 PolarHBondContact O-NH2 2.93Å; I353-F365 HydrophobicContact CD1-CD2 4.04Å; I353-F365 HydrophobicContact CD1-CE2 3.74Å; I353-L368 HydrophobicContact CD1-CD2 3.95Å; I353-L368 HydrophobicContact CG1-CD2 3.71Å; I353-F402 HydrophobicContact CD1-CE2 4.33Å; I353-F402 HydrophobicContact CD1-CZ 4.24Å; I353-V406 HydrophobicContact CD1-CG2 3.9Å; I353-L409 HydrophobicContact CG2-CD1 3.94Å; I353-F417 HydrophobicContact CG2-CE1 3.65Å; I353-F417 HydrophobicContact CG2-CZ 3.85Å
354L98.9Very high98.4Very high0 Ų011.5 Ų11.50%06%0.056CC..Hα-helixtrans-69.3-34.7176.7-62.9178.9000112.4A320 L350 A351 C352 R360 L409 L487 L488 P490A320-L354 HydrophobicContact CB-CD1 4.25Å; L350-L354 WeakPolarHBondContact O-CG 3.39Å; L350-L354 PolarHBondContact O-N 3.24Å; A351-L354 PolarHBondContact O-N 3.2Å; C352-L354 VanDerWaalsContact C-N 3.29Å; C352-L354 PolarHBondContact O-N 3.16Å; L354-R360 PolarHBondContact O-NH2 2.77Å; L354-L409 HydrophobicContact CD2-CD1 3.95Å; L354-L409 HydrophobicContact CD2-CD2 3.87Å; L354-L487 WeakPolarHBondContact O-CA 3.46Å; L354-L488 HydrophobicContact CD2-CB 3.76Å; L354-L488 PolarHBondContact O-N 3.2Å; L354-P490 HydrophobicContact CD1-CG 4.23Å; L354-P490 HydrophobicContact CD2-CG 4.25Å
355L98.7Very high98.4Very high2 Ų211.5 Ų11.51%0.016%0.056CC..Hα-helixtrans-84.5-31.4-175.1-77.6165.1000114.6Y192 Y194 I201 S324 V327 A351 C352 L487Y192-L355 HydrophobicContact CD1-CD1 4.15Å; Y192-L355 HydrophobicContact CE1-CB 4.1Å; Y192-L355 HydrophobicContact CE1-CD1 3.91Å; Y194-L355 HydrophobicContact CD2-CD2 4.19Å; Y194-L355 HydrophobicContact CE2-CD2 4.08Å; I201-L355 HydrophobicContact CD1-CD1 3.75Å; S324-L355 WeakPolarHBondContact O-CD2 3Å; S324-L355 WeakPolarHBondContact OG-CG 3.25Å; V327-L355 HydrophobicContact CB-CD1 4.05Å; V327-L355 HydrophobicContact CB-CD2 4.27Å; V327-L355 HydrophobicContact CG1-CD1 3.88Å; V327-L355 HydrophobicContact CG1-CD2 4.1Å; A351-L355 WeakPolarHBondContact O-CB 3.18Å; A351-L355 WeakPolarHBondContact O-CD1 3.03Å; A351-L355 VanDerWaalsContact O-CG 3.3Å; A351-L355 WeakPolarHBondContact O-CG 3.42Å; A351-L355 PolarHBondContact O-N 3.16Å; C352-L355 PolarHBondContact O-N 2.91Å; C352-L355 VanDerWaalsContact O-N 3.12Å; L355-L487 HydrophobicContact CD2-CD2 3.94Å
356D98.2Very high98.3Very high20 Ų2012.2 Ų12.211%0.1076%0.059CC..  trans-134113.9-167.7-166.8-19.6000111.5R137 Y192 C352 Y358 Y359R137-D356 IonicContact CZ-OD2 2.66Å; R137-D356 VanDerWaalsContact CZ-OD2 3.31Å; R137-D356 IonicContact NH1-OD1 3.64Å; R137-D356 IonicContact NH1-OD2 3.65Å; R137-D356 PolarHBondContact NH1-OD2 3.22Å; R137-D356 IonicContact NH2-OD2 3.94Å; R137-D356 PolarHBondContact NH2-OD2 2.69Å; Y192-D356 HydrophobicContact CE2-CB 4.07Å; Y192-D356 WeakPolarHBondContact OH-CB 3.37Å; C352-D356 PolarHBondContact O-N 3.05Å; D356-Y358 PolarHBondContact O-N 3.09Å; D356-Y358 VanDerWaalsContact O-N 3.13Å; D356-Y358 WeakPolarHBondContact OD1-CB 3.4Å; D356-Y358 PolarHBondContact OD1-N 2.84Å; D356-Y359 HydrophobicContact CB-CD2 3.62Å; D356-Y359 HydrophobicContact CB-CE2 3.79Å; D356-Y359 PolarHBondContact O-N 2.97Å
357P98Very high98.3Very high22 Ų2212.3 Ų12.314%0.1436%0.059CC..G310 helixtrans-58.4-23.9176.4-24.134.9000113.7Y359 R360 V484 S485P357-Y359 VanDerWaalsContact C-N 3.27Å; P357-Y359 PolarHBondContact O-N 3.33Å; P357-R360 WeakPolarHBondContact O-CB 3.21Å; P357-R360 PolarHBondContact O-N 3.26Å; P357-V484 HydrophobicContact CB-CG2 4.03Å; P357-S485 WeakPolarHBondContact CG-O 3.21Å
358Y97.7Very high98.2Very high55 Ų5512.3 Ų12.322%0.2166%0.059CC..G310 helixtrans-54.5-44.5176.2172.6-108.5000111.6R137 D356 R360 T361 K363 G364 V367R137-Y358 VanDerWaalsContact NE-CE1 3.3Å; D356-Y358 PolarHBondContact O-N 3.09Å; D356-Y358 VanDerWaalsContact O-N 3.13Å; D356-Y358 WeakPolarHBondContact OD1-CB 3.4Å; D356-Y358 PolarHBondContact OD1-N 2.84Å; Y358-R360 PolarHBondContact O-N 3.36Å; Y358-R360 VanDerWaalsContact O-N 3.13Å; Y358-T361 WeakPolarHBondContact O-CB 3.35Å; Y358-T361 PolarHBondContact O-N 2.96Å; Y358-T361 PolarHBondContact O-OG1 3.05Å; Y358-K363 HydrophobicContact CE2-CG 4.48Å; Y358-G364 VanDerWaalsContact CZ-CA 3.47Å; Y358-G364 WeakPolarHBondContact O-CA 3.48Å; Y358-V367 HydrophobicContact CE1-CG1 4.39Å
359Y98.5Very high98.2Very high0 Ų012.3 Ų12.30%06%0.059CC..G310 helixtrans-72.1-4.4-179-57.1-55.6000114.1D134 R137 Y192 C352 D356 P357 G364 F365 L368D134-Y359 VanDerWaalsContact CG-OH 3.31Å; D134-Y359 PolarHBondContact OD1-OH 3.37Å; D134-Y359 WeakPolarHBondContact OD2-CE1 3.48Å; D134-Y359 PolarHBondContact OD2-OH 3.44Å; R137-Y359 PolarHBondContact NH2-OH 2.85Å; Y192-Y359 AromaticContact CD2-CE2 3.87Å; Y192-Y359 HydrophobicContact CD2-CE2 3.87Å; Y192-Y359 AromaticContact CE2-CE2 3.73Å; Y192-Y359 HydrophobicContact CE2-CE2 3.73Å; C352-Y359 HydrophobicContact CB-CD2 3.6Å; C352-Y359 HydrophobicContact CB-CE2 3.57Å; C352-Y359 HydrophobicContact CB-CG 4.48Å; C352-Y359 WeakPolarHBondContact O-CD2 3.46Å; D356-Y359 HydrophobicContact CB-CD2 3.62Å; D356-Y359 HydrophobicContact CB-CE2 3.79Å; D356-Y359 PolarHBondContact O-N 2.97Å; P357-Y359 VanDerWaalsContact C-N 3.27Å; P357-Y359 PolarHBondContact O-N 3.33Å; Y359-G364 WeakPolarHBondContact CD1-O 3.33Å; Y359-F365 WeakPolarHBondContact O-CB 3.38Å; Y359-L368 HydrophobicContact CD1-CB 3.74Å; Y359-L368 HydrophobicContact CD1-CD1 4.16Å; Y359-L368 HydrophobicContact CD1-CD2 4.31Å; Y359-L368 HydrophobicContact CD1-CG 4.3Å; Y359-L368 HydrophobicContact CE1-CB 4.15Å; Y359-L368 HydrophobicContact CE1-CD1 4.06Å; Y359-L368 HydrophobicContact CG-CB 4.39Å; Y359-L368 HydrophobicContact CG-CD1 4.45Å; Y359-L368 HydrophobicContact CG-CD2 4.14Å
360R98.5Very high98.1Very high1 Ų112.9 Ų12.90%0.0046%0.062CC..G310 helixtrans-91.1-8.2171.7-49.9-177.5-159.3140.715.3112.6I353 L354 P357 Y358 E416 F417 E418 S485 L488I353-R360 HydrophobicContact CG2-CG 4.22Å; I353-R360 PolarHBondContact O-NE 3.49Å; I353-R360 PolarHBondContact O-NH2 2.93Å; L354-R360 PolarHBondContact O-NH2 2.77Å; P357-R360 WeakPolarHBondContact O-CB 3.21Å; P357-R360 PolarHBondContact O-N 3.26Å; Y358-R360 PolarHBondContact O-N 3.36Å; Y358-R360 VanDerWaalsContact O-N 3.13Å; R360-E416 VanDerWaalsContact CB-O 3.25Å; R360-E416 WeakPolarHBondContact CB-O 3.33Å; R360-E416 WeakPolarHBondContact CD-O 3.38Å; R360-E416 IonicContact NH1-OE2 3.43Å; R360-E416 PolarHBondContact NH1-OE2 3.41Å; R360-F417 HydrophobicContact CB-CD1 3.72Å; R360-F417 HydrophobicContact CB-CE1 4.02Å; R360-F417 HydrophobicContact CB-CG 4.3Å; R360-F417 HydrophobicContact CG-CD1 4Å; R360-F417 HydrophobicContact CG-CE1 3.76Å; R360-F417 HydrophobicContact CG-CZ 4.26Å; R360-E418 PolarHBondContact O-N 3.19Å; R360-S485 PolarHBondContact NH1-O 2.84Å; R360-L488 VanDerWaalsContact CZ-CD1 3.47Å; R360-L488 VanDerWaalsContact NE-CD1 3.31Å
361T97.9Very high98Very high30 Ų3012.9 Ų12.918%0.1846%0.062CC..SBendtrans-78.2155.6167.971.60000110.2Y358 K363 G364 F365 E418Y358-T361 WeakPolarHBondContact O-CB 3.35Å; Y358-T361 PolarHBondContact O-N 2.96Å; Y358-T361 PolarHBondContact O-OG1 3.05Å; T361-K363 PolarHBondContact O-N 2.85Å; T361-G364 PolarHBondContact O-N 3.32Å; T361-G364 PolarHBondContact OG1-N 3.17Å; T361-F365 VanDerWaalsContact O-CB 3.27Å; T361-F365 WeakPolarHBondContact O-CB 3.47Å; T361-F365 PolarHBondContact O-N 2.9Å; T361-E418 VanDerWaalsContact CA-OE2 3.31Å; T361-E418 WeakPolarHBondContact CA-OE2 3.31Å; T361-E418 VanDerWaalsContact CB-OE2 3.25Å; T361-E418 WeakPolarHBondContact CB-OE2 3.38Å
362I97.4Very high98Very high25 Ų2512.9 Ų12.913%0.1286%0.062CC..Hα-helixtrans-55-47.5172.5-72167.3000109.3F365 Q366 E418 F419 Y423I362-F365 PolarHBondContact O-N 3.41Å; I362-Q366 VanDerWaalsContact O-CG 3.28Å; I362-Q366 WeakPolarHBondContact O-CG 3.45Å; I362-Q366 PolarHBondContact O-N 3.39Å; I362-Q366 VanDerWaalsContact O-N 3.07Å; I362-E418 HydrophobicContact CD1-CG 4.14Å; I362-E418 HydrophobicContact CG1-CB 4.41Å; I362-E418 HydrophobicContact CG1-CG 4.14Å; I362-E418 PolarHBondContact N-OE2 3.28Å; I362-F419 HydrophobicContact CG1-CB 3.88Å; I362-Y423 HydrophobicContact CG1-CD2 4.45Å; I362-Y423 HydrophobicContact CG1-CE2 4.3Å; I362-Y423 HydrophobicContact CG2-CE2 3.91Å
363K96.1Very high98Very high86 Ų8612.9 Ų12.937%0.3746%0.062SC..Hα-helixtrans-60.2-53.5-179.5179.259.7173.8-168.40111.6D128 N129 Y358 T361 F365 Q366 V367D128-K363 VanDerWaalsContact C-NZ 3.32Å; D128-K363 PolarHBondContact O-NZ 3.46Å; N129-K363 WeakPolarHBondContact OD1-CD 2.99Å; N129-K363 WeakPolarHBondContact OD1-CE 3.43Å; N129-K363 PolarHBondContact OD1-NZ 3.35Å; Y358-K363 HydrophobicContact CE2-CG 4.48Å; T361-K363 PolarHBondContact O-N 2.85Å; K363-F365 VanDerWaalsContact C-N 3.34Å; K363-F365 PolarHBondContact O-N 2.89Å; K363-Q366 PolarHBondContact O-N 3.06Å; K363-V367 HydrophobicContact CD-CG2 4.42Å; K363-V367 WeakPolarHBondContact O-CG2 3.49Å; K363-V367 PolarHBondContact O-N 3.36Å
364G97.5Very high97.8Very high0 Ų013.1 Ų13.10%06%0.064CC..Hα-helixtrans-65.8-37.1-177.700000112.6Y358 Y359 T361 V367 L368Y358-G364 VanDerWaalsContact CZ-CA 3.47Å; Y358-G364 WeakPolarHBondContact O-CA 3.48Å; Y359-G364 WeakPolarHBondContact CD1-O 3.33Å; T361-G364 PolarHBondContact O-N 3.32Å; T361-G364 PolarHBondContact OG1-N 3.17Å; G364-V367 PolarHBondContact O-N 3.26Å; G364-L368 WeakPolarHBondContact O-CB 3.19Å; G364-L368 PolarHBondContact O-N 3.18Å
365F98.3Very high97.7Very high0 Ų013.3 Ų13.30%06%0.064CC..Hα-helixtrans-65.3-40176.5-168.6-113.7000112.5I353 Y359 T361 I362 K363 L368 I369 F402 L403 V406 F419 Y423 L424 L427I353-F365 HydrophobicContact CD1-CD2 4.04Å; I353-F365 HydrophobicContact CD1-CE2 3.74Å; Y359-F365 WeakPolarHBondContact O-CB 3.38Å; T361-F365 VanDerWaalsContact O-CB 3.27Å; T361-F365 WeakPolarHBondContact O-CB 3.47Å; T361-F365 PolarHBondContact O-N 2.9Å; I362-F365 PolarHBondContact O-N 3.41Å; K363-F365 VanDerWaalsContact C-N 3.34Å; K363-F365 PolarHBondContact O-N 2.89Å; F365-L368 PolarHBondContact O-N 3.39Å; F365-I369 HydrophobicContact CD1-CD1 3.75Å; F365-I369 HydrophobicContact CE1-CD1 3.55Å; F365-I369 HydrophobicContact CG-CD1 4.44Å; F365-I369 HydrophobicContact CZ-CD1 4.06Å; F365-I369 WeakPolarHBondContact O-CG1 3.47Å; F365-I369 PolarHBondContact O-N 3.22Å; F365-F402 HydrophobicContact CE2-CE1 4.08Å; F365-F402 AromaticContact CE2-CZ 3.79Å; F365-F402 HydrophobicContact CE2-CZ 3.79Å; F365-F402 AromaticContact CZ-CE1 3.86Å; F365-F402 HydrophobicContact CZ-CE1 3.86Å; F365-F402 HydrophobicContact CZ-CZ 4.05Å; F365-L403 HydrophobicContact CE1-CD2 4.47Å; F365-L403 HydrophobicContact CZ-CD2 4.24Å; F365-V406 HydrophobicContact CE2-CG1 4.06Å; F365-V406 HydrophobicContact CE2-CG2 3.98Å; F365-V406 HydrophobicContact CZ-CG1 4.1Å; F365-V406 HydrophobicContact CZ-CG2 4.14Å; F365-F419 HydrophobicContact CB-CD1 4.16Å; F365-F419 HydrophobicContact CB-CE1 3.64Å; F365-F419 HydrophobicContact CB-CZ 4.44Å; F365-F419 HydrophobicContact CD1-CD1 4.47Å; F365-F419 HydrophobicContact CD1-CE1 4.05Å; F365-F419 HydrophobicContact CD1-CZ 4.23Å; F365-F419 HydrophobicContact CD2-CE1 4Å; F365-F419 AromaticContact CD2-CZ 3.98Å; F365-F419 HydrophobicContact CD2-CZ 3.98Å; F365-F419 HydrophobicContact CE1-CZ 4.46Å; F365-F419 HydrophobicContact CE2-CZ 4.25Å; F365-F419 HydrophobicContact CG-CD1 4.36Å; F365-F419 AromaticContact CG-CE1 3.64Å; F365-F419 HydrophobicContact CG-CE1 3.64Å; F365-F419 AromaticContact CG-CZ 3.97Å; F365-F419 HydrophobicContact CG-CZ 3.97Å; F365-F419 HydrophobicContact CZ-CZ 4.48Å; F365-Y423 AromaticContact CD1-CE1 3.67Å; F365-Y423 HydrophobicContact CD1-CE1 3.67Å; F365-Y423 AromaticContact CE1-CE1 3.97Å; F365-Y423 HydrophobicContact CE1-CE1 3.97Å; F365-L424 HydrophobicContact CE1-CD2 3.8Å; F365-L424 HydrophobicContact CZ-CD2 3.92Å; F365-L427 HydrophobicContact CD1-CD1 4.3Å; F365-L427 HydrophobicContact CE1-CD1 3.61Å
366Q97.8Very high97.6Very high16 Ų1613.2 Ų13.28%0.0756%0.064CC..Hα-helixtrans-62.6-46.1173.1-70175.4-7.500111.8N129 I362 K363 L368 I369 E370 Y423 W464N129-Q366 HydrophobicContact CB-CB 4.36Å; N129-Q366 PolarHBondContact ND2-OE1 2.77Å; I362-Q366 VanDerWaalsContact O-CG 3.28Å; I362-Q366 WeakPolarHBondContact O-CG 3.45Å; I362-Q366 PolarHBondContact O-N 3.39Å; I362-Q366 VanDerWaalsContact O-N 3.07Å; K363-Q366 PolarHBondContact O-N 3.06Å; Q366-L368 VanDerWaalsContact C-N 3.3Å; Q366-L368 PolarHBondContact O-N 3.4Å; Q366-I369 PolarHBondContact O-N 2.74Å; Q366-E370 WeakPolarHBondContact O-CG 3.46Å; Q366-E370 PolarHBondContact O-N 2.83Å; Q366-Y423 WeakPolarHBondContact CG-OH 3.39Å; Q366-Y423 PolarHBondContact NE2-OH 3.02Å; Q366-W464 HydrophobicContact CB-CD2 4.43Å; Q366-W464 HydrophobicContact CG-CD2 4.08Å; Q366-W464 HydrophobicContact CG-CE3 3.72Å; Q366-W464 HydrophobicContact CG-CH2 4.27Å; Q366-W464 HydrophobicContact CG-CZ3 3.83Å
367V97.7Very high97.5Very high1 Ų112.4 Ų12.41%0.0066%0.06CC..Hα-helixtrans-61.2-38.6176.3167.30000111.7N129 D134 Y358 K363 G364 E370 K371N129-V367 HydrophobicContact CB-CG2 4.1Å; D134-V367 HydrophobicContact CB-CG1 3.51Å; Y358-V367 HydrophobicContact CE1-CG1 4.39Å; K363-V367 HydrophobicContact CD-CG2 4.42Å; K363-V367 WeakPolarHBondContact O-CG2 3.49Å; K363-V367 PolarHBondContact O-N 3.36Å; G364-V367 PolarHBondContact O-N 3.26Å; V367-E370 PolarHBondContact O-N 2.74Å; V367-K371 WeakPolarHBondContact O-CB 3.22Å; V367-K371 PolarHBondContact O-N 3.23Å
368L98.3Very high97.6Very high0 Ų011.4 Ų11.40%05%0.054CC..Hα-helixtrans-63.4-42.4175-176.764.7000111.8C352 I353 Y359 G364 F365 Q366 E372C352-L368 HydrophobicContact CB-CD1 3.96Å; C352-L368 HydrophobicContact CB-CD2 4.41Å; I353-L368 HydrophobicContact CD1-CD2 3.95Å; I353-L368 HydrophobicContact CG1-CD2 3.71Å; Y359-L368 HydrophobicContact CD1-CB 3.74Å; Y359-L368 HydrophobicContact CD1-CD1 4.16Å; Y359-L368 HydrophobicContact CD1-CD2 4.31Å; Y359-L368 HydrophobicContact CD1-CG 4.3Å; Y359-L368 HydrophobicContact CE1-CB 4.15Å; Y359-L368 HydrophobicContact CE1-CD1 4.06Å; Y359-L368 HydrophobicContact CG-CB 4.39Å; Y359-L368 HydrophobicContact CG-CD1 4.45Å; Y359-L368 HydrophobicContact CG-CD2 4.14Å; G364-L368 WeakPolarHBondContact O-CB 3.19Å; G364-L368 PolarHBondContact O-N 3.18Å; F365-L368 PolarHBondContact O-N 3.39Å; Q366-L368 VanDerWaalsContact C-N 3.3Å; Q366-L368 PolarHBondContact O-N 3.4Å; L368-E372 HydrophobicContact CD1-CG 3.74Å; L368-E372 WeakPolarHBondContact O-CB 3.29Å; L368-E372 PolarHBondContact O-N 3.46Å
369I98.3Very high97.5Very high0 Ų010.8 Ų10.80%05%0.052CC..Hα-helixtrans-64.3-49.5175.5-67.8163.3000110.4F365 Q366 K371 W373 L374 F399 L427 F439 W464F365-I369 HydrophobicContact CD1-CD1 3.75Å; F365-I369 HydrophobicContact CE1-CD1 3.55Å; F365-I369 HydrophobicContact CG-CD1 4.44Å; F365-I369 HydrophobicContact CZ-CD1 4.06Å; F365-I369 WeakPolarHBondContact O-CG1 3.47Å; F365-I369 PolarHBondContact O-N 3.22Å; Q366-I369 PolarHBondContact O-N 2.74Å; I369-K371 VanDerWaalsContact C-N 3.29Å; I369-K371 PolarHBondContact O-N 3.28Å; I369-W373 HydrophobicContact CG2-CB 4.38Å; I369-W373 WeakPolarHBondContact O-CA 3.4Å; I369-W373 VanDerWaalsContact O-CB 3.24Å; I369-W373 WeakPolarHBondContact O-CB 3.22Å; I369-W373 PolarHBondContact O-N 3.43Å; I369-L374 HydrophobicContact CG2-CD1 4.11Å; I369-L374 HydrophobicContact CG2-CG 4.46Å; I369-L374 PolarHBondContact O-N 2.87Å; I369-L374 VanDerWaalsContact O-N 3.12Å; I369-F399 HydrophobicContact CD1-CZ 3.94Å; I369-F399 HydrophobicContact CG1-CE2 4.29Å; I369-F399 HydrophobicContact CG1-CZ 4.05Å; I369-F399 HydrophobicContact CG2-CE2 4.25Å; I369-F399 HydrophobicContact CG2-CZ 4.02Å; I369-L427 HydrophobicContact CD1-CD1 3.97Å; I369-F439 HydrophobicContact CG2-CE1 3.82Å; I369-F439 HydrophobicContact CG2-CZ 4.24Å; I369-W464 HydrophobicContact CD1-CH2 4.3Å; I369-W464 HydrophobicContact CG2-CH2 4.32Å; I369-W464 HydrophobicContact CG2-CZ2 4.25Å
370E96.9Very high97.5Very high12 Ų1210.8 Ų10.86%0.0565%0.052CC..Iπ-helixtrans-55.9-43.5177-77-72.9171.100111.9N129 Q366 V367 L374 M375 R447 W464N129-E370 HydrophobicContact CB-CG 3.98Å; N129-E370 VanDerWaalsContact O-CB 3.26Å; N129-E370 WeakPolarHBondContact O-CB 3.31Å; N129-E370 WeakPolarHBondContact O-CG 3.2Å; Q366-E370 WeakPolarHBondContact O-CG 3.46Å; Q366-E370 PolarHBondContact O-N 2.83Å; V367-E370 PolarHBondContact O-N 2.74Å; E370-L374 HydrophobicContact CG-CD1 4.08Å; E370-L374 WeakPolarHBondContact O-CB 3.45Å; E370-L374 PolarHBondContact O-N 3.48Å; E370-L374 WeakPolarHBondContact OE1-CD1 3.43Å; E370-L374 WeakPolarHBondContact OE2-CD1 3.21Å; E370-M375 WeakPolarHBondContact O-CB 3.36Å; E370-M375 VanDerWaalsContact O-CG 3.31Å; E370-M375 WeakPolarHBondContact O-CG 3.49Å; E370-M375 PolarHBondContact O-N 2.98Å; E370-R447 IonicContact OE1-NH2 3.72Å; E370-R447 IonicContact OE2-CZ 2.88Å; E370-R447 IonicContact OE2-NH1 3.47Å; E370-R447 IonicContact OE2-NH2 3.23Å; E370-R447 PolarHBondContact OE2-NH2 2.93Å; E370-W464 HydrophobicContact CG-CZ2 4.48Å; E370-W464 PolarHBondContact OE1-NE1 2.84Å
371K97.5Very high97.3Very high0 Ų011.1 Ų11.10%05%0.054CC..Iπ-helixtrans-73-67177.9-171.7-179.762.7168.10112.2D134 Y135 S191 V367 I369 W373 M375 Y376D134-K371 HydrophobicContact CB-CD 4.27Å; D134-K371 WeakPolarHBondContact OD2-CE 3.48Å; D134-K371 IonicContact OD2-NZ 3.61Å; D134-K371 PolarHBondContact OD2-NZ 2.72Å; Y135-K371 HydrophobicContact CE1-CD 4.39Å; Y135-K371 HydrophobicContact CE2-CD 3.98Å; Y135-K371 HydrophobicContact CE2-CG 4.43Å; S191-K371 PolarHBondContact O-NZ 3.34Å; V367-K371 WeakPolarHBondContact O-CB 3.22Å; V367-K371 PolarHBondContact O-N 3.23Å; I369-K371 VanDerWaalsContact C-N 3.29Å; I369-K371 PolarHBondContact O-N 3.28Å; K371-W373 PolarHBondContact O-N 2.97Å; K371-M375 WeakPolarHBondContact O-CB 3.46Å; K371-Y376 HydrophobicContact CG-CD2 4.49Å; K371-Y376 HydrophobicContact CG-CE2 4.2Å; K371-Y376 VanDerWaalsContact O-CD2 3.23Å; K371-Y376 WeakPolarHBondContact O-CD2 3.25Å; K371-Y376 PolarHBondContact O-N 3.03Å
372E98.2Very high97.2Very high0 Ų012 Ų120%06%0.058CC..Iπ-helixtrans-74.6-26.7-165.7-66.6-60.1139.100113.1S191 R203 P345 V348 S349 L368S191-E372 VanDerWaalsContact CB-OE1 3.27Å; S191-E372 WeakPolarHBondContact CB-OE1 3.26Å; S191-E372 PolarHBondContact OG-OE1 3.14Å; S191-E372 VanDerWaalsContact OG-OE1 3.07Å; S191-E372 PolarHBondContact OG-OE2 2.87Å; S191-E372 VanDerWaalsContact OG-OE2 3.06Å; R203-E372 WeakPolarHBondContact CD-OE2 3.2Å; R203-E372 IonicContact CZ-OE2 3.83Å; R203-E372 IonicContact NE-OE2 2.94Å; R203-E372 PolarHBondContact NH1-O 3.21Å; R203-E372 IonicContact NH1-OE2 3.98Å; R203-E372 PolarHBondContact NH1-OE2 3.34Å; P345-E372 HydrophobicContact CB-CB 4.5Å; P345-E372 WeakPolarHBondContact CB-O 3.29Å; V348-E372 HydrophobicContact CG1-CG 4.28Å; V348-E372 WeakPolarHBondContact CG1-OE2 3.46Å; S349-E372 WeakPolarHBondContact OG-CB 3.39Å; L368-E372 HydrophobicContact CD1-CG 3.74Å; L368-E372 WeakPolarHBondContact O-CB 3.29Å; L368-E372 PolarHBondContact O-N 3.46Å
373W98.4Very high97.1Very high0 Ų011 Ų110%05%0.053CC..Iπ-helixtrans-102.4-49.3-177.2-6377.6000111.8P345 Q346 S349 I369 K371 G377 H378 F380 I398 F399 F402P345-W373 HydrophobicContact CB-CD2 4.04Å; P345-W373 HydrophobicContact CB-CE3 4.32Å; P345-W373 HydrophobicContact CB-CG 4.43Å; P345-W373 HydrophobicContact CB-CZ2 4.36Å; P345-W373 HydrophobicContact CG-CE3 4.32Å; P345-W373 HydrophobicContact CG-CZ3 4.37Å; Q346-W373 HydrophobicContact CB-CH2 4.44Å; Q346-W373 HydrophobicContact CB-CZ2 4.48Å; Q346-W373 HydrophobicContact CG-CH2 3.49Å; Q346-W373 VanDerWaalsContact CG-CH2 3.49Å; Q346-W373 HydrophobicContact CG-CZ2 3.97Å; S349-W373 PolarHBondContact OG-NE1 3.2Å; I369-W373 HydrophobicContact CG2-CB 4.38Å; I369-W373 WeakPolarHBondContact O-CA 3.4Å; I369-W373 VanDerWaalsContact O-CB 3.24Å; I369-W373 WeakPolarHBondContact O-CB 3.22Å; I369-W373 PolarHBondContact O-N 3.43Å; K371-W373 PolarHBondContact O-N 2.97Å; W373-G377 PolarHBondContact O-N 3.3Å; W373-H378 HydrophobicContact CB-CB 4.37Å; W373-H378 HydrophobicContact CE3-CB 3.77Å; W373-H378 AromaticContact CE3-CD2 3.67Å; W373-H378 AromaticContact CE3-CG 3.5Å; W373-H378 VanDerWaalsContact CE3-CG 3.5Å; W373-H378 AromaticContact CE3-ND1 3.95Å; W373-H378 AromaticContact CZ3-CD2 3.88Å; W373-H378 AromaticContact CZ3-CE1 3.88Å; W373-H378 AromaticContact CZ3-CG 3.81Å; W373-H378 AromaticContact CZ3-ND1 3.81Å; W373-H378 AromaticContact CZ3-NE2 3.92Å; W373-H378 VanDerWaalsContact O-CB 3.31Å; W373-H378 WeakPolarHBondContact O-CB 3.38Å; W373-H378 PolarHBondContact O-N 3.16Å; W373-F380 HydrophobicContact CB-CE2 3.87Å; W373-F380 HydrophobicContact CB-CZ 3.9Å; W373-F380 HydrophobicContact CE3-CZ 4.15Å; W373-I398 HydrophobicContact CH2-CG2 4.31Å; W373-I398 HydrophobicContact CZ3-CG2 4.17Å; W373-F399 AromaticContact CD2-CD2 3.56Å; W373-F399 HydrophobicContact CD2-CD2 3.56Å; W373-F399 AromaticContact CD2-CE2 3.67Å; W373-F399 HydrophobicContact CD2-CE2 3.67Å; W373-F399 AromaticContact CE2-CD2 3.79Å; W373-F399 AromaticContact CE2-CE2 3.8Å; W373-F399 AromaticContact CE3-CD2 3.46Å; W373-F399 HydrophobicContact CE3-CD2 3.46Å; W373-F399 VanDerWaalsContact CE3-CD2 3.46Å; W373-F399 HydrophobicContact CE3-CE2 4.05Å; W373-F399 HydrophobicContact CE3-CG 4.49Å; W373-F399 HydrophobicContact CG-CD2 4.27Å; W373-F399 AromaticContact CG-CE2 3.94Å; W373-F399 HydrophobicContact CG-CE2 3.94Å; W373-F399 AromaticContact CH2-CD2 3.74Å; W373-F399 HydrophobicContact CH2-CD2 3.74Å; W373-F399 AromaticContact CZ2-CD2 3.89Å; W373-F399 HydrophobicContact CZ2-CD2 3.89Å; W373-F399 HydrophobicContact CZ2-CE2 4.24Å; W373-F399 HydrophobicContact CZ3-CB 4.17Å; W373-F399 AromaticContact CZ3-CD2 3.56Å; W373-F399 HydrophobicContact CZ3-CD2 3.56Å; W373-F399 HydrophobicContact CZ3-CE2 4.47Å; W373-F399 HydrophobicContact CZ3-CG 4.36Å; W373-F402 HydrophobicContact CH2-CB 3.72Å; W373-F402 HydrophobicContact CH2-CD1 4.38Å; W373-F402 HydrophobicContact CH2-CG 4.08Å; W373-F402 HydrophobicContact CZ2-CB 3.57Å; W373-F402 AromaticContact CZ2-CD1 3.61Å; W373-F402 HydrophobicContact CZ2-CD1 3.61Å; W373-F402 AromaticContact CZ2-CD2 3.85Å; W373-F402 HydrophobicContact CZ2-CD2 3.85Å; W373-F402 HydrophobicContact CZ2-CE1 4.23Å; W373-F402 HydrophobicContact CZ2-CE2 4.44Å; W373-F402 AromaticContact CZ2-CG 3.39Å; W373-F402 HydrophobicContact CZ2-CG 3.39Å; W373-F402 AromaticContact NE1-CE1 3.99Å
374L96Very high97.1Very high6 Ų67.1 Ų7.13%0.0314%0.036CC..Iπ-helixtrans-85.5-51.6-170.3-57.9167.4000112I369 E370 Y376 G377 F380 T438 F439 R447I369-L374 HydrophobicContact CG2-CD1 4.11Å; I369-L374 HydrophobicContact CG2-CG 4.46Å; I369-L374 PolarHBondContact O-N 2.87Å; I369-L374 VanDerWaalsContact O-N 3.12Å; E370-L374 HydrophobicContact CG-CD1 4.08Å; E370-L374 WeakPolarHBondContact O-CB 3.45Å; E370-L374 PolarHBondContact O-N 3.48Å; E370-L374 WeakPolarHBondContact OE1-CD1 3.43Å; E370-L374 WeakPolarHBondContact OE2-CD1 3.21Å; L374-Y376 PolarHBondContact O-N 3.47Å; L374-G377 PolarHBondContact O-N 3.32Å; L374-F380 HydrophobicContact CD2-CD2 3.64Å; L374-F380 HydrophobicContact CD2-CE2 3.26Å; L374-F380 HydrophobicContact CD2-CZ 4.08Å; L374-F380 HydrophobicContact CG-CE2 4.18Å; L374-T438 HydrophobicContact CD1-CG2 4.05Å; L374-T438 WeakPolarHBondContact CD2-O 3.46Å; L374-F439 HydrophobicContact CD1-CE1 4.24Å; L374-F439 HydrophobicContact CD2-CD1 3.88Å; L374-F439 HydrophobicContact CD2-CE1 4.23Å; L374-R447 VanDerWaalsContact CB-NH1 3.29Å
375M95.4Very high96.9Very high4 Ų48.7 Ų8.72%0.025%0.049CC..Iπ-helixtrans-65.2-40.4178.1-73.1174.660.100112.4G131 Y132 P161 E370 K371 G377 H444G131-M375 WeakPolarHBondContact CA-SD 3.44Å; Y132-M375 HydrophobicContact CD1-CE 3.93Å; Y132-M375 HydrophobicContact CD2-CE 3.96Å; Y132-M375 HydrophobicContact CE1-CE 3.58Å; Y132-M375 HydrophobicContact CE2-CE 3.64Å; Y132-M375 HydrophobicContact CG-CE 4.11Å; Y132-M375 VanDerWaalsContact CZ-CE 3.44Å; P161-M375 HydrophobicContact CB-CB 4.29Å; P161-M375 HydrophobicContact CB-CE 3.92Å; P161-M375 WeakPolarHBondContact CD-O 3.21Å; P161-M375 HydrophobicContact CG-CB 4.45Å; P161-M375 HydrophobicContact CG-CE 4.15Å; E370-M375 WeakPolarHBondContact O-CB 3.36Å; E370-M375 VanDerWaalsContact O-CG 3.31Å; E370-M375 WeakPolarHBondContact O-CG 3.49Å; E370-M375 PolarHBondContact O-N 2.98Å; K371-M375 WeakPolarHBondContact O-CB 3.46Å; M375-G377 VanDerWaalsContact C-N 3.28Å; M375-G377 PolarHBondContact O-N 2.78Å; M375-H444 WeakPolarHBondContact O-CB 3Å
376Y97.7Very high96.7Very high0 Ų08.8 Ų8.80%05%0.049CC..THydrogen-bonded Turntrans-90.118.1179.2-74.2-71.4000114.5Y135 G159 Y160 P161 R186 V189 K371 L374Y135-Y376 WeakPolarHBondContact OH-CE2 3.38Å; Y135-Y376 PolarHBondContact OH-OH 3.06Å; G159-Y376 CarbonylContact O-C 3.59Å; Y160-Y376 AromaticContact CD1-CD1 3.64Å; Y160-Y376 HydrophobicContact CD1-CD1 3.64Å; Y160-Y376 HydrophobicContact CD1-CE1 4.21Å; Y160-Y376 AromaticContact CE1-CD1 3.81Å; Y160-Y376 HydrophobicContact CE1-CD1 3.81Å; Y160-Y376 HydrophobicContact CE1-CE1 4.35Å; Y160-Y376 HydrophobicContact CG-CD1 4.16Å; Y160-Y376 HydrophobicContact CG-CE1 4.33Å; P161-Y376 VanDerWaalsContact CD-CE1 3.5Å; P161-Y376 HydrophobicContact CG-CD1 4.34Å; P161-Y376 HydrophobicContact CG-CE1 3.92Å; R186-Y376 PolarHBondContact NH1-O 2.87Å; R186-Y376 PolarHBondContact NH2-O 2.85Å; V189-Y376 HydrophobicContact CG2-CE1 3.66Å; K371-Y376 HydrophobicContact CG-CD2 4.49Å; K371-Y376 HydrophobicContact CG-CE2 4.2Å; K371-Y376 VanDerWaalsContact O-CD2 3.23Å; K371-Y376 WeakPolarHBondContact O-CD2 3.25Å; K371-Y376 PolarHBondContact O-N 3.03Å; L374-Y376 PolarHBondContact O-N 3.47Å
377G96.5Very high96.4Very high2 Ų29.7 Ų9.72%0.0216%0.056CC..THydrogen-bonded Turntrans67.848.7160.700000115.3G159 W341 W373 L374 M375 N442G159-G377 PolarHBondContact O-N 2.96Å; W341-G377 WeakPolarHBondContact CB-O 3.32Å; W373-G377 PolarHBondContact O-N 3.3Å; L374-G377 PolarHBondContact O-N 3.32Å; M375-G377 VanDerWaalsContact C-N 3.28Å; M375-G377 PolarHBondContact O-N 2.78Å; G377-N442 CarbonylContact C-O 3.58Å
378H98.3Very high95.8Very high2 Ų215.1 Ų15.11%0.0098%0.077CC..  trans-63.2132.4158.2-177.765.5000109.3W341 D342 W373 F380W341-H378 PolarHBondContact O-ND1 3.4Å; D342-H378 IonicContact OD1-CE1 3.93Å; D342-H378 PolarHBondContact OD1-CE1 3.05Å; D342-H378 VanDerWaalsContact OD1-CE1 3.29Å; D342-H378 IonicContact OD1-ND1 3.9Å; W373-H378 HydrophobicContact CB-CB 4.37Å; W373-H378 HydrophobicContact CE3-CB 3.77Å; W373-H378 AromaticContact CE3-CD2 3.67Å; W373-H378 AromaticContact CE3-CG 3.5Å; W373-H378 VanDerWaalsContact CE3-CG 3.5Å; W373-H378 AromaticContact CE3-ND1 3.95Å; W373-H378 AromaticContact CZ3-CD2 3.88Å; W373-H378 AromaticContact CZ3-CE1 3.88Å; W373-H378 AromaticContact CZ3-CG 3.81Å; W373-H378 AromaticContact CZ3-ND1 3.81Å; W373-H378 AromaticContact CZ3-NE2 3.92Å; W373-H378 VanDerWaalsContact O-CB 3.31Å; W373-H378 WeakPolarHBondContact O-CB 3.38Å; W373-H378 PolarHBondContact O-N 3.16Å; H378-F380 VanDerWaalsContact C-N 3.26Å; H378-F380 HydrophobicContact CB-CD2 4.18Å; H378-F380 HydrophobicContact CB-CE2 3.92Å; H378-F380 AromaticContact CD2-CD1 3.79Å; H378-F380 AromaticContact CD2-CD2 3.73Å; H378-F380 AromaticContact CD2-CE1 3.79Å; H378-F380 AromaticContact CD2-CE2 3.69Å; H378-F380 AromaticContact CD2-CG 3.77Å; H378-F380 AromaticContact CD2-CZ 3.75Å; H378-F380 WeakPolarHBondContact O-CD2 3.41Å; H378-F380 PolarHBondContact O-N 3.16Å
379K97Very high95Very high41 Ų4118.6 Ų18.618%0.17810%0.101CC..  trans-80.464.9-172.4-59.8-16972.7-164.60112.3W341 S381 D382 R383 N442W341-K379 HydrophobicContact CD2-CD 4.46Å; W341-K379 HydrophobicContact CH2-CD 4.24Å; W341-K379 HydrophobicContact CZ2-CD 3.95Å; K379-S381 PolarHBondContact O-N 2.68Å; K379-D382 HydrophobicContact CB-CB 4.22Å; K379-D382 WeakPolarHBondContact CE-OD2 3.39Å; K379-D382 IonicContact NZ-OD2 2.58Å; K379-D382 PolarHBondContact NZ-OD2 3.46Å; K379-D382 PolarHBondContact O-N 3.22Å; K379-R383 HydrophobicContact CB-CG 4.41Å; K379-R383 WeakPolarHBondContact O-CB 3.39Å; K379-R383 WeakPolarHBondContact O-CG 3.31Å; K379-R383 PolarHBondContact O-N 2.77Å; K379-N442 WeakPolarHBondContact CA-OD1 3.5Å; K379-N442 HydrophobicContact CB-CB 4.17Å; K379-N442 WeakPolarHBondContact CB-OD1 3.1Å; K379-N442 HydrophobicContact CG-CB 4.27Å; K379-N442 PolarHBondContact O-OD1 3.4Å
380F97.2Very high93.7Very high1 Ų123 Ų230%0.00414%0.137CC..Hα-helixtrans-55.9-46.8-172.7-79.8-81.3000113.6W373 L374 H378 D382 R383 C384 F399 L431 F439 N442W373-F380 HydrophobicContact CB-CE2 3.87Å; W373-F380 HydrophobicContact CB-CZ 3.9Å; W373-F380 HydrophobicContact CE3-CZ 4.15Å; L374-F380 HydrophobicContact CD2-CD2 3.64Å; L374-F380 HydrophobicContact CD2-CE2 3.26Å; L374-F380 HydrophobicContact CD2-CZ 4.08Å; L374-F380 HydrophobicContact CG-CE2 4.18Å; H378-F380 VanDerWaalsContact C-N 3.26Å; H378-F380 HydrophobicContact CB-CD2 4.18Å; H378-F380 HydrophobicContact CB-CE2 3.92Å; H378-F380 AromaticContact CD2-CD1 3.79Å; H378-F380 AromaticContact CD2-CD2 3.73Å; H378-F380 AromaticContact CD2-CE1 3.79Å; H378-F380 AromaticContact CD2-CE2 3.69Å; H378-F380 AromaticContact CD2-CG 3.77Å; H378-F380 AromaticContact CD2-CZ 3.75Å; H378-F380 WeakPolarHBondContact O-CD2 3.41Å; H378-F380 PolarHBondContact O-N 3.16Å; F380-D382 VanDerWaalsContact C-N 3.34Å; F380-D382 PolarHBondContact O-N 3.21Å; F380-R383 PolarHBondContact O-N 3.39Å; F380-C384 WeakPolarHBondContact O-CB 3.5Å; F380-C384 PolarHBondContact O-N 2.76Å; F380-C384 PolarHBondContact O-SG 3.34Å; F380-C384 VanDerWaalsContact O-SG 3.33Å; F380-F399 HydrophobicContact CE1-CB 3.95Å; F380-F399 HydrophobicContact CE1-CD1 4.08Å; F380-F399 AromaticContact CE1-CD2 3.93Å; F380-F399 HydrophobicContact CE1-CD2 3.93Å; F380-F399 HydrophobicContact CE1-CE2 4.43Å; F380-F399 AromaticContact CE1-CG 3.72Å; F380-F399 HydrophobicContact CE1-CG 3.72Å; F380-F399 AromaticContact CZ-CD2 3.92Å; F380-F399 HydrophobicContact CZ-CD2 3.92Å; F380-F399 HydrophobicContact CZ-CE2 4.16Å; F380-F399 HydrophobicContact CZ-CG 4.2Å; F380-L431 HydrophobicContact CD1-CD1 3.44Å; F380-L431 VanDerWaalsContact CD1-CD1 3.44Å; F380-L431 HydrophobicContact CE1-CD1 3.56Å; F380-F439 WeakPolarHBondContact CB-O 3.49Å; F380-F439 HydrophobicContact CD1-CB 4.13Å; F380-F439 AromaticContact CD1-CD1 3.99Å; F380-F439 HydrophobicContact CD1-CD1 3.99Å; F380-F439 HydrophobicContact CD1-CG 4.36Å; F380-F439 HydrophobicContact CD2-CD1 4.41Å; F380-F439 AromaticContact CE1-CD1 3.62Å; F380-F439 HydrophobicContact CE1-CD1 3.62Å; F380-F439 HydrophobicContact CE1-CE1 4.13Å; F380-F439 HydrophobicContact CE1-CG 4.31Å; F380-F439 HydrophobicContact CE2-CD1 4.09Å; F380-F439 HydrophobicContact CG-CB 4.32Å; F380-F439 HydrophobicContact CG-CD1 4.36Å; F380-F439 AromaticContact CZ-CD1 3.67Å; F380-F439 HydrophobicContact CZ-CD1 3.67Å; F380-F439 AromaticContact CZ-CE1 3.96Å; F380-F439 HydrophobicContact CZ-CE1 3.96Å; F380-N442 PolarHBondContact N-OD1 2.97Å
381S95.1Very high92.7Very high7 Ų726.1 Ų26.15%0.04915%0.154CC..Hα-helixtrans-56.7-47.4179.4-166.40000112.2K379 A385 H386 L440 N442K379-S381 PolarHBondContact O-N 2.68Å; S381-A385 WeakPolarHBondContact O-CA 3.49Å; S381-A385 PolarHBondContact O-N 3.01Å; S381-H386 VanDerWaalsContact CA-CD2 3.5Å; S381-H386 WeakPolarHBondContact CA-CD2 3.33Å; S381-H386 PolarHBondContact O-N 3.04Å; S381-L440 WeakPolarHBondContact CB-O 3.35Å; S381-N442 WeakPolarHBondContact CB-OD1 3.44Å; S381-N442 PolarHBondContact N-OD1 3.38Å
382D95.3Very high92Very high48 Ų4830 Ų3026%0.25718%0.182SC..Hα-helixtrans-71.4-42.7-178.5-67.56.1000111.7K379 F380 C384 E394 N442K379-D382 HydrophobicContact CB-CB 4.22Å; K379-D382 WeakPolarHBondContact CE-OD2 3.39Å; K379-D382 IonicContact NZ-OD2 2.58Å; K379-D382 PolarHBondContact NZ-OD2 3.46Å; K379-D382 PolarHBondContact O-N 3.22Å; F380-D382 VanDerWaalsContact C-N 3.34Å; F380-D382 PolarHBondContact O-N 3.21Å; D382-C384 VanDerWaalsContact C-N 3.31Å; D382-C384 PolarHBondContact O-N 3.21Å; D382-E394 HydrophobicContact CB-CB 4.19Å; D382-N442 VanDerWaalsContact CG-ND2 3.31Å; D382-N442 PolarHBondContact N-OD1 3.42Å; D382-N442 VanDerWaalsContact N-OD1 3.08Å; D382-N442 PolarHBondContact OD1-ND2 2.82Å
383R96.3Very high91.7Very high6 Ų636.1 Ų36.12%0.02321%0.208CC..Hα-helixtrans-68.8-32.5-177.5-65.4-71.2173.2-88.53.2112D342 K379 F380 E394 V395 A396D342-R383 IonicContact OD1-CZ 2.82Å; D342-R383 IonicContact OD1-NE 3.57Å; D342-R383 PolarHBondContact OD1-NE 2.95Å; D342-R383 IonicContact OD1-NH2 3.98Å; D342-R383 IonicContact OD2-CZ 3.56Å; D342-R383 IonicContact OD2-NE 3.97Å; D342-R383 PolarHBondContact OD2-NE 3.2Å; D342-R383 IonicContact OD2-NH2 3.54Å; D342-R383 PolarHBondContact OD2-NH2 3.4Å; K379-R383 HydrophobicContact CB-CG 4.41Å; K379-R383 WeakPolarHBondContact O-CB 3.39Å; K379-R383 WeakPolarHBondContact O-CG 3.31Å; K379-R383 PolarHBondContact O-N 2.77Å; F380-R383 PolarHBondContact O-N 3.39Å; R383-E394 WeakPolarHBondContact CD-O 3.41Å; R383-E394 IonicContact CZ-OE2 3.55Å; R383-E394 PolarHBondContact NH1-O 3.26Å; R383-E394 IonicContact NH1-OE2 2.73Å; R383-E394 PolarHBondContact NH1-OE2 2.85Å; R383-E394 IonicContact NH2-OE2 2.7Å; R383-E394 PolarHBondContact NH2-OE2 2.83Å; R383-V395 WeakPolarHBondContact O-CG1 3.49Å; R383-A396 PolarHBondContact O-N 3.2Å
384C95Very high91.5Very high4 Ų439.2 Ų39.23%0.02722%0.223CC..Hα-helixtrans-102.11.4-176.8-56.70000114F380 D382 H386 Y432F380-C384 WeakPolarHBondContact O-CB 3.5Å; F380-C384 PolarHBondContact O-N 2.76Å; F380-C384 PolarHBondContact O-SG 3.34Å; F380-C384 VanDerWaalsContact O-SG 3.33Å; D382-C384 VanDerWaalsContact C-N 3.31Å; D382-C384 PolarHBondContact O-N 3.21Å; C384-H386 VanDerWaalsContact C-N 3.34Å; C384-H386 WeakPolarHBondContact CB-CE1 3.48Å; C384-H386 PolarHBondContact O-N 2.78Å; C384-Y432 HydrophobicContact CB-CD1 3.88Å; C384-Y432 HydrophobicContact CB-CE1 3.66Å
385A94Very high91.5Very high32 Ų3241.1 Ų41.126%0.26424%0.235SC..THydrogen-bonded Turntrans49.752.7-175.300000111.8K74 S381 V395K74-A385 PolarHBondContact NZ-O 3.24Å; S381-A385 WeakPolarHBondContact O-CA 3.49Å; S381-A385 PolarHBondContact O-N 3.01Å; A385-V395 HydrophobicContact CB-CG2 3.82Å
386H93Very high91.5Very high2 Ų241 Ų411%0.00924%0.235CC..SBendtrans-67.3-48.4176.6-66-24.4000110.4P102 L108 S381 C384 L431 C434 F439P102-H386 WeakPolarHBondContact CG-O 3.42Å; L108-H386 HydrophobicContact CD1-CB 4.07Å; L108-H386 WeakPolarHBondContact CD2-O 3.43Å; S381-H386 VanDerWaalsContact CA-CD2 3.5Å; S381-H386 WeakPolarHBondContact CA-CD2 3.33Å; S381-H386 PolarHBondContact O-N 3.04Å; C384-H386 VanDerWaalsContact C-N 3.34Å; C384-H386 WeakPolarHBondContact CB-CE1 3.48Å; C384-H386 PolarHBondContact O-N 2.78Å; H386-L431 PolarHBondContact CE1-O 3.47Å; H386-C434 PolarHBondContact ND1-SG 2.69Å; H386-F439 PolarHBondContact CD2-O 3.25Å; H386-F439 PolarHBondContact NE2-O 3.47Å
387V91.4Very high91.5Very high35 Ų3541.4 Ų41.421%0.21224%0.237CC..SBendtrans-98.9137.3171.5-178.10000109S103 I105 S389S103-V387 VanDerWaalsContact O-CG1 3.3Å; S103-V387 WeakPolarHBondContact O-CG1 3.41Å; I105-V387 HydrophobicContact CG1-CG2 3.64Å; V387-S389 PolarHBondContact O-N 3.06Å
388Y85.9Confident91.6Very high115 Ų11541.4 Ų41.445%0.45124%0.237SC..  trans-67125.5177.6178.2-101.9000110.7R101 P102R101-Y388 HydrophobicContact CB-CD1 4.38Å; R101-Y388 HydrophobicContact CB-CD2 3.94Å; R101-Y388 HydrophobicContact CB-CG 3.75Å; R101-Y388 VanDerWaalsContact CD-CE2 3.48Å; R101-Y388 HydrophobicContact CG-CD2 3.52Å; R101-Y388 HydrophobicContact CG-CE2 4Å; R101-Y388 HydrophobicContact CG-CG 3.9Å; R101-Y388 PolarHBondContact NH1-OH 2.92Å; P102-Y388 WeakPolarHBondContact O-CB 3.45Å; P102-Y388 PolarHBondContact O-N 3.26Å
389S82Confident91.6Very high74 Ų7441.4 Ų41.452%0.51724%0.236SC..  trans-122.9137.6169.4175.20000108.7V387 D391V387-S389 PolarHBondContact O-N 3.06Å; S389-D391 PolarHBondContact O-N 2.87Å; S389-D391 PolarHBondContact OG-N 3.3Å
390A71.4Confident91.7Very high91 Ų9139.5 Ų39.575%0.75223%0.228SC*.SBendtrans-61-25.2173.800000112S392A390-S392 PolarHBondContact O-N 3.18Å
391D75.8Confident91.8Very high78 Ų7839.5 Ų39.542%0.41723%0.228SC..  trans-91.597.7173.4-168.92.6000111.4S389 K393S389-D391 PolarHBondContact O-N 2.87Å; S389-D391 PolarHBondContact OG-N 3.3Å; D391-K393 PolarHBondContact O-N 3.44Å; D391-K393 WeakPolarHBondContact OD1-CB 3.33Å; D391-K393 WeakPolarHBondContact OD1-CD 3.46Å; D391-K393 WeakPolarHBondContact OD1-CG 3.46Å; D391-K393 PolarHBondContact OD1-N 2.89Å
392S82.7Confident91.9Very high82 Ų8239.1 Ų39.157%0.57323%0.226SC*.G310 helixtrans-76.30.1176.463.90000113.7R279 A390 E394 V395R279-S392 PolarHBondContact NH1-O 3.28Å; A390-S392 PolarHBondContact O-N 3.18Å; S392-E394 PolarHBondContact O-N 3.01Å; S392-V395 PolarHBondContact O-N 3.33Å
393K92Very high92.1Very high128 Ų12836.9 Ų36.956%0.55721%0.213SC*.G310 helixtrans-66-24.2-174.9-69.8171.3-172.7170.20114H276 R279 D391H276-K393 PolarHBondContact CE1-O 3.07Å; H276-K393 PolarHBondContact ND1-O 3.12Å; R279-K393 PolarHBondContact NH1-O 3.45Å; R279-K393 VanDerWaalsContact NH1-O 3.08Å; D391-K393 PolarHBondContact O-N 3.44Å; D391-K393 WeakPolarHBondContact OD1-CB 3.33Å; D391-K393 WeakPolarHBondContact OD1-CD 3.46Å; D391-K393 WeakPolarHBondContact OD1-CG 3.46Å; D391-K393 PolarHBondContact OD1-N 2.89Å
394E94.2Very high92.2Very high66 Ų6636.6 Ų36.631%0.30821%0.212SC..G310 helixtrans-80.6-15.9-179.9-70.7-63.4125.200114.2D382 R383 S392 A396D382-E394 HydrophobicContact CB-CB 4.19Å; R383-E394 WeakPolarHBondContact CD-O 3.41Å; R383-E394 IonicContact CZ-OE2 3.55Å; R383-E394 PolarHBondContact NH1-O 3.26Å; R383-E394 IonicContact NH1-OE2 2.73Å; R383-E394 PolarHBondContact NH1-OE2 2.85Å; R383-E394 IonicContact NH2-OE2 2.7Å; R383-E394 PolarHBondContact NH2-OE2 2.83Å; S392-E394 PolarHBondContact O-N 3.01Å; E394-A396 PolarHBondContact O-N 2.87Å
395V94.9Very high92.4Very high46 Ų4636.4 Ų36.428%0.27921%0.211SC..  trans-70127.4-178.9-177.30000110R279 R383 A385 S392R279-V395 VanDerWaalsContact CD-O 3.31Å; R279-V395 WeakPolarHBondContact CD-O 2.9Å; R279-V395 PolarHBondContact NH1-O 3.44Å; R383-V395 WeakPolarHBondContact O-CG1 3.49Å; A385-V395 HydrophobicContact CB-CG2 3.82Å; S392-V395 PolarHBondContact O-N 3.33Å
396A96.8Very high92.6Very high2 Ų234.9 Ų34.92%0.01720%0.198CC..  trans-162.4145.4173.900000112I275 R279 R383 E394 I398I275-A396 HydrophobicContact CB-CB 3.59Å; I275-A396 HydrophobicContact CG2-CB 4.27Å; I275-A396 WeakPolarHBondContact O-CB 3.37Å; R279-A396 HydrophobicContact CB-CB 4.44Å; R383-A396 PolarHBondContact O-N 3.2Å; E394-A396 PolarHBondContact O-N 2.87Å; A396-I398 HydrophobicContact CB-CD1 4.02Å; A396-I398 HydrophobicContact CB-CG1 3.93Å; A396-I398 PolarHBondContact O-N 3.14Å
397P97Very high92.9Very high8 Ų835.2 Ų35.25%0.05220%0.2CC..  trans-81.448.8-173.638.1-41.1000112.4V278 L282 W309 T400 Q401V278-P397 HydrophobicContact CG1-CG 3.92Å; L282-P397 HydrophobicContact CB-CG 4.03Å; L282-P397 HydrophobicContact CD2-CB 3.47Å; L282-P397 VanDerWaalsContact CD2-CB 3.47Å; L282-P397 HydrophobicContact CD2-CG 3.44Å; L282-P397 VanDerWaalsContact CD2-CG 3.44Å; L282-P397 HydrophobicContact CG-CG 4.36Å; W309-P397 HydrophobicContact CH2-CG 4.23Å; W309-P397 HydrophobicContact CZ3-CG 4.3Å; P397-T400 PolarHBondContact O-N 3.49Å; P397-Q401 VanDerWaalsContact O-CB 3.31Å; P397-Q401 WeakPolarHBondContact O-CB 3.47Å; P397-Q401 PolarHBondContact O-N 3.22Å
398I98.7Very high93.3Very high2 Ų233.7 Ų33.71%0.0119%0.19CC..Hα-helixtrans-66.7-46.7-170.9-58.7-55.6000112I275 V278 D342 Q346 W373 A396 Q401 F402I275-I398 HydrophobicContact CB-CD1 4.45Å; I275-I398 HydrophobicContact CG2-CD1 3.98Å; I275-I398 HydrophobicContact CG2-CG1 4.14Å; V278-I398 HydrophobicContact CB-CD1 4.37Å; V278-I398 HydrophobicContact CG1-CD1 4.24Å; D342-I398 HydrophobicContact CB-CG2 4.11Å; Q346-I398 HydrophobicContact CG-CG2 4.02Å; Q346-I398 PolarHBondContact NE2-O 2.88Å; W373-I398 HydrophobicContact CH2-CG2 4.31Å; W373-I398 HydrophobicContact CZ3-CG2 4.17Å; A396-I398 HydrophobicContact CB-CD1 4.02Å; A396-I398 HydrophobicContact CB-CG1 3.93Å; A396-I398 PolarHBondContact O-N 3.14Å; I398-Q401 PolarHBondContact O-N 3.4Å; I398-F402 PolarHBondContact O-N 2.93Å; I398-F402 VanDerWaalsContact O-N 3.11Å
399F98.7Very high93.9Very high2 Ų228.2 Ų28.21%0.00917%0.169CC..Hα-helixtrans-68.6-39.8175.7-165.3-110.7000111.5I369 W373 F380 Q401 F402 L403 L431 F439I369-F399 HydrophobicContact CD1-CZ 3.94Å; I369-F399 HydrophobicContact CG1-CE2 4.29Å; I369-F399 HydrophobicContact CG1-CZ 4.05Å; I369-F399 HydrophobicContact CG2-CE2 4.25Å; I369-F399 HydrophobicContact CG2-CZ 4.02Å; W373-F399 AromaticContact CD2-CD2 3.56Å; W373-F399 HydrophobicContact CD2-CD2 3.56Å; W373-F399 AromaticContact CD2-CE2 3.67Å; W373-F399 HydrophobicContact CD2-CE2 3.67Å; W373-F399 AromaticContact CE2-CD2 3.79Å; W373-F399 AromaticContact CE2-CE2 3.8Å; W373-F399 AromaticContact CE3-CD2 3.46Å; W373-F399 HydrophobicContact CE3-CD2 3.46Å; W373-F399 VanDerWaalsContact CE3-CD2 3.46Å; W373-F399 HydrophobicContact CE3-CE2 4.05Å; W373-F399 HydrophobicContact CE3-CG 4.49Å; W373-F399 HydrophobicContact CG-CD2 4.27Å; W373-F399 AromaticContact CG-CE2 3.94Å; W373-F399 HydrophobicContact CG-CE2 3.94Å; W373-F399 AromaticContact CH2-CD2 3.74Å; W373-F399 HydrophobicContact CH2-CD2 3.74Å; W373-F399 AromaticContact CZ2-CD2 3.89Å; W373-F399 HydrophobicContact CZ2-CD2 3.89Å; W373-F399 HydrophobicContact CZ2-CE2 4.24Å; W373-F399 HydrophobicContact CZ3-CB 4.17Å; W373-F399 AromaticContact CZ3-CD2 3.56Å; W373-F399 HydrophobicContact CZ3-CD2 3.56Å; W373-F399 HydrophobicContact CZ3-CE2 4.47Å; W373-F399 HydrophobicContact CZ3-CG 4.36Å; F380-F399 HydrophobicContact CE1-CB 3.95Å; F380-F399 HydrophobicContact CE1-CD1 4.08Å; F380-F399 AromaticContact CE1-CD2 3.93Å; F380-F399 HydrophobicContact CE1-CD2 3.93Å; F380-F399 HydrophobicContact CE1-CE2 4.43Å; F380-F399 AromaticContact CE1-CG 3.72Å; F380-F399 HydrophobicContact CE1-CG 3.72Å; F380-F399 AromaticContact CZ-CD2 3.92Å; F380-F399 HydrophobicContact CZ-CD2 3.92Å; F380-F399 HydrophobicContact CZ-CE2 4.16Å; F380-F399 HydrophobicContact CZ-CG 4.2Å; F399-Q401 VanDerWaalsContact C-N 3.31Å; F399-Q401 PolarHBondContact O-N 2.93Å; F399-F402 AromaticContact CD2-CD1 3.98Å; F399-F402 HydrophobicContact CD2-CD1 3.98Å; F399-F402 AromaticContact CE2-CD1 3.75Å; F399-F402 HydrophobicContact CE2-CD1 3.75Å; F399-F402 HydrophobicContact CE2-CE1 4.01Å; F399-F402 HydrophobicContact CZ-CD1 4.33Å; F399-F402 HydrophobicContact CZ-CE1 4.44Å; F399-F402 WeakPolarHBondContact O-CA 3.46Å; F399-F402 WeakPolarHBondContact O-CB 3Å; F399-F402 PolarHBondContact O-N 3.35Å; F399-F402 VanDerWaalsContact O-N 3.08Å; F399-L403 HydrophobicContact CD1-CD1 3.9Å; F399-L403 HydrophobicContact CD1-CG 4.13Å; F399-L403 HydrophobicContact CE1-CD1 3.86Å; F399-L403 HydrophobicContact CE1-CD2 4.02Å; F399-L403 HydrophobicContact CE1-CG 4.04Å; F399-L403 HydrophobicContact CZ-CD2 4.23Å; F399-L403 WeakPolarHBondContact O-CG 3Å; F399-L403 PolarHBondContact O-N 3.26Å; F399-L431 HydrophobicContact CB-CD2 4.16Å; F399-L431 HydrophobicContact CD1-CD1 3.99Å; F399-L431 HydrophobicContact CD1-CD2 4.01Å; F399-F439 HydrophobicContact CE1-CE1 4.49Å; F399-F439 HydrophobicContact CE1-CZ 4.29Å; F399-F439 HydrophobicContact CZ-CE1 4.42Å; F399-F439 HydrophobicContact CZ-CZ 4.42Å
400T98.3Very high94.6Very high0 Ų025.2 Ų25.20%015%0.147CC..Hα-helixtrans-58.9-41.2173.7-58.90000112.2F76 P397 F402 L403 D404 Q428 Y432 L503F76-T400 HydrophobicContact CE2-CG2 4.17Å; F76-T400 HydrophobicContact CZ-CG2 4.03Å; P397-T400 PolarHBondContact O-N 3.49Å; T400-F402 VanDerWaalsContact C-N 3.32Å; T400-F402 PolarHBondContact O-N 3.36Å; T400-L403 PolarHBondContact O-N 2.94Å; T400-D404 PolarHBondContact O-N 3.32Å; T400-Q428 HydrophobicContact CG2-CG 3.96Å; T400-Y432 PolarHBondContact OG1-OH 3.35Å; T400-Y432 VanDerWaalsContact OG1-OH 3.13Å; T400-L503 HydrophobicContact CG2-CD2 4.24Å
401Q98.6Very high95.8Very high1 Ų125.8 Ų25.81%0.00514%0.135CC..Hα-helixtrans-63.8-37.1174.5-169.4-172.442.500112.2W309 I313 L316 P397 I398 F399 D404 A405W309-Q401 HydrophobicContact CH2-CB 3.79Å; W309-Q401 HydrophobicContact CH2-CG 3.87Å; W309-Q401 HydrophobicContact CZ2-CB 4.23Å; W309-Q401 HydrophobicContact CZ2-CG 4.17Å; W309-Q401 HydrophobicContact CZ3-CG 4.49Å; I313-Q401 HydrophobicContact CD1-CG 3.56Å; L316-Q401 HydrophobicContact CD1-CG 3.72Å; P397-Q401 VanDerWaalsContact O-CB 3.31Å; P397-Q401 WeakPolarHBondContact O-CB 3.47Å; P397-Q401 PolarHBondContact O-N 3.22Å; I398-Q401 PolarHBondContact O-N 3.4Å; F399-Q401 VanDerWaalsContact C-N 3.31Å; F399-Q401 PolarHBondContact O-N 2.93Å; Q401-D404 PolarHBondContact O-N 3.18Å; Q401-A405 PolarHBondContact O-N 2.66Å
402F98.9Very high96.8Very high0 Ų024 Ų240%012%0.124CC..Hα-helixtrans-64.2-45.4172.3163.1-108.3000111.7Q346 S349 L350 I353 F365 W373 I398 F399 T400 D404 A405 V406Q346-F402 HydrophobicContact CG-CB 4.19Å; S349-F402 VanDerWaalsContact CB-CE2 3.5Å; L350-F402 HydrophobicContact CD1-CD2 4.5Å; L350-F402 HydrophobicContact CD2-CD2 4.19Å; L350-F402 HydrophobicContact CD2-CE2 4.05Å; L350-F402 HydrophobicContact CG-CD2 3.97Å; L350-F402 HydrophobicContact CG-CE2 3.96Å; I353-F402 HydrophobicContact CD1-CE2 4.33Å; I353-F402 HydrophobicContact CD1-CZ 4.24Å; F365-F402 HydrophobicContact CE2-CE1 4.08Å; F365-F402 AromaticContact CE2-CZ 3.79Å; F365-F402 HydrophobicContact CE2-CZ 3.79Å; F365-F402 AromaticContact CZ-CE1 3.86Å; F365-F402 HydrophobicContact CZ-CE1 3.86Å; F365-F402 HydrophobicContact CZ-CZ 4.05Å; W373-F402 HydrophobicContact CH2-CB 3.72Å; W373-F402 HydrophobicContact CH2-CD1 4.38Å; W373-F402 HydrophobicContact CH2-CG 4.08Å; W373-F402 HydrophobicContact CZ2-CB 3.57Å; W373-F402 AromaticContact CZ2-CD1 3.61Å; W373-F402 HydrophobicContact CZ2-CD1 3.61Å; W373-F402 AromaticContact CZ2-CD2 3.85Å; W373-F402 HydrophobicContact CZ2-CD2 3.85Å; W373-F402 HydrophobicContact CZ2-CE1 4.23Å; W373-F402 HydrophobicContact CZ2-CE2 4.44Å; W373-F402 AromaticContact CZ2-CG 3.39Å; W373-F402 HydrophobicContact CZ2-CG 3.39Å; W373-F402 AromaticContact NE1-CE1 3.99Å; I398-F402 PolarHBondContact O-N 2.93Å; I398-F402 VanDerWaalsContact O-N 3.11Å; F399-F402 AromaticContact CD2-CD1 3.98Å; F399-F402 HydrophobicContact CD2-CD1 3.98Å; F399-F402 AromaticContact CE2-CD1 3.75Å; F399-F402 HydrophobicContact CE2-CD1 3.75Å; F399-F402 HydrophobicContact CE2-CE1 4.01Å; F399-F402 HydrophobicContact CZ-CD1 4.33Å; F399-F402 HydrophobicContact CZ-CE1 4.44Å; F399-F402 WeakPolarHBondContact O-CA 3.46Å; F399-F402 WeakPolarHBondContact O-CB 3Å; F399-F402 PolarHBondContact O-N 3.35Å; F399-F402 VanDerWaalsContact O-N 3.08Å; T400-F402 VanDerWaalsContact C-N 3.32Å; T400-F402 PolarHBondContact O-N 3.36Å; F402-D404 VanDerWaalsContact C-N 3.28Å; F402-D404 PolarHBondContact O-N 3.22Å; F402-A405 PolarHBondContact O-N 3.2Å; F402-A405 VanDerWaalsContact O-N 3.17Å; F402-V406 HydrophobicContact CD2-CG2 4.07Å; F402-V406 HydrophobicContact CE1-CG2 4.13Å; F402-V406 HydrophobicContact CE2-CG2 3.6Å; F402-V406 HydrophobicContact CZ-CG2 3.64Å; F402-V406 WeakPolarHBondContact O-CG2 3.43Å; F402-V406 PolarHBondContact O-N 3.29Å
403L98.9Very high97.5Very high0 Ų022.1 Ų22.10%011%0.105CC..Hα-helixtrans-61.1-37.9177.3-64.8177.3000111.8F365 F399 T400 V406 W407 L424 L427 Q428 W500F365-L403 HydrophobicContact CE1-CD2 4.47Å; F365-L403 HydrophobicContact CZ-CD2 4.24Å; F399-L403 HydrophobicContact CD1-CD1 3.9Å; F399-L403 HydrophobicContact CD1-CG 4.13Å; F399-L403 HydrophobicContact CE1-CD1 3.86Å; F399-L403 HydrophobicContact CE1-CD2 4.02Å; F399-L403 HydrophobicContact CE1-CG 4.04Å; F399-L403 HydrophobicContact CZ-CD2 4.23Å; F399-L403 WeakPolarHBondContact O-CG 3Å; F399-L403 PolarHBondContact O-N 3.26Å; T400-L403 PolarHBondContact O-N 2.94Å; L403-V406 PolarHBondContact O-N 2.89Å; L403-W407 WeakPolarHBondContact O-CB 3.47Å; L403-W407 PolarHBondContact O-N 3.44Å; L403-L424 HydrophobicContact CD2-CD2 4.04Å; L403-L427 HydrophobicContact CD1-CB 3.99Å; L403-L427 HydrophobicContact CD2-CB 4.42Å; L403-L427 HydrophobicContact CD2-CD1 3.93Å; L403-Q428 HydrophobicContact CD1-CB 3.8Å; L403-Q428 HydrophobicContact CD1-CG 4.46Å; L403-W500 HydrophobicContact CB-CH2 4.41Å; L403-W500 HydrophobicContact CB-CZ3 4.14Å
404D98.7Very high97.6Very high0 Ų019.2 Ų19.20%010%0.099CC..Hα-helixtrans-61.9-49.2172.7-174.7-24.3000110.5W309 I313 T400 Q401 F402 V406 W407 Q408 W500 Y504W309-D404 PolarHBondContact NE1-OD2 3.04Å; I313-D404 HydrophobicContact CD1-CB 3.73Å; T400-D404 PolarHBondContact O-N 3.32Å; Q401-D404 PolarHBondContact O-N 3.18Å; F402-D404 VanDerWaalsContact C-N 3.28Å; F402-D404 PolarHBondContact O-N 3.22Å; D404-V406 VanDerWaalsContact C-N 3.27Å; D404-V406 PolarHBondContact O-N 3.47Å; D404-W407 CarbonylContact O-C 3.58Å; D404-W407 WeakPolarHBondContact O-CA 3.43Å; D404-W407 WeakPolarHBondContact O-CB 3.36Å; D404-W407 PolarHBondContact O-N 3.46Å; D404-Q408 WeakPolarHBondContact O-CG 3.47Å; D404-Q408 PolarHBondContact O-N 3.37Å; D404-Q408 PolarHBondContact OD1-NE2 3.37Å; D404-W500 HydrophobicContact CB-CE3 3.84Å; D404-W500 HydrophobicContact CB-CZ3 4.2Å; D404-Y504 WeakPolarHBondContact OD2-CE2 3.46Å; D404-Y504 PolarHBondContact OD2-OH 2.87Å; D404-Y504 VanDerWaalsContact OD2-OH 3.05Å
405A98.9Very high97.7Very high0 Ų019 Ų190%010%0.103CC..Hα-helixtrans-58.5-37175.500000113.1I313 L316 L317 L350 Q401 F402 Q408 L409I313-A405 HydrophobicContact CG2-CB 4.36Å; L316-A405 HydrophobicContact CB-CB 4.47Å; L316-A405 HydrophobicContact CD1-CB 4.31Å; L317-A405 HydrophobicContact CD2-CB 4.14Å; L317-A405 HydrophobicContact CG-CB 4.34Å; L350-A405 HydrophobicContact CD1-CB 3.77Å; L350-A405 HydrophobicContact CD2-CB 3.95Å; L350-A405 HydrophobicContact CG-CB 4.49Å; Q401-A405 PolarHBondContact O-N 2.66Å; F402-A405 PolarHBondContact O-N 3.2Å; F402-A405 VanDerWaalsContact O-N 3.17Å; A405-Q408 PolarHBondContact O-N 2.68Å; A405-L409 PolarHBondContact O-N 3.08Å
406V98.9Very high97.8Very high0 Ų017.4 Ų17.40%09%0.092CC..Hα-helixtrans-67-40.9172.7176.80000111L350 I353 F365 F402 L403 D404 Q408 L409 V410 F419 L424L350-V406 HydrophobicContact CD2-CG2 3.85Å; I353-V406 HydrophobicContact CD1-CG2 3.9Å; F365-V406 HydrophobicContact CE2-CG1 4.06Å; F365-V406 HydrophobicContact CE2-CG2 3.98Å; F365-V406 HydrophobicContact CZ-CG1 4.1Å; F365-V406 HydrophobicContact CZ-CG2 4.14Å; F402-V406 HydrophobicContact CD2-CG2 4.07Å; F402-V406 HydrophobicContact CE1-CG2 4.13Å; F402-V406 HydrophobicContact CE2-CG2 3.6Å; F402-V406 HydrophobicContact CZ-CG2 3.64Å; F402-V406 WeakPolarHBondContact O-CG2 3.43Å; F402-V406 PolarHBondContact O-N 3.29Å; L403-V406 PolarHBondContact O-N 2.89Å; D404-V406 VanDerWaalsContact C-N 3.27Å; D404-V406 PolarHBondContact O-N 3.47Å; V406-Q408 VanDerWaalsContact C-N 3.32Å; V406-Q408 PolarHBondContact O-N 3.06Å; V406-L409 WeakPolarHBondContact O-CA 3.48Å; V406-L409 WeakPolarHBondContact O-CB 3.48Å; V406-L409 PolarHBondContact O-N 3.13Å; V406-V410 WeakPolarHBondContact O-CG2 3.1Å; V406-V410 PolarHBondContact O-N 2.69Å; V406-F419 HydrophobicContact CG1-CE2 3.88Å; V406-F419 HydrophobicContact CG1-CZ 3.94Å; V406-L424 HydrophobicContact CB-CD1 4.42Å; V406-L424 HydrophobicContact CB-CD2 4.42Å; V406-L424 HydrophobicContact CG1-CD1 4.02Å; V406-L424 HydrophobicContact CG1-CD2 3.87Å
407W98.6Very high97.9Very high10 Ų1017.3 Ų17.34%0.0389%0.091CC..Hα-helixtrans-60.5-40.2175.1175.780.8000112.1L403 D404 L409 V410 E411 E421 L424 T498 W500L403-W407 WeakPolarHBondContact O-CB 3.47Å; L403-W407 PolarHBondContact O-N 3.44Å; D404-W407 CarbonylContact O-C 3.58Å; D404-W407 WeakPolarHBondContact O-CA 3.43Å; D404-W407 WeakPolarHBondContact O-CB 3.36Å; D404-W407 PolarHBondContact O-N 3.46Å; W407-L409 PolarHBondContact O-N 3.16Å; W407-V410 WeakPolarHBondContact O-CB 3.38Å; W407-V410 PolarHBondContact O-N 3.2Å; W407-E411 HydrophobicContact CD2-CG 3.88Å; W407-E411 HydrophobicContact CE3-CG 4.25Å; W407-E411 HydrophobicContact CH2-CG 3.76Å; W407-E411 HydrophobicContact CZ2-CG 3.35Å; W407-E411 HydrophobicContact CZ3-CG 4.18Å; W407-E411 PolarHBondContact O-N 2.88Å; W407-E421 PolarHBondContact NE1-OE1 3.28Å; W407-L424 HydrophobicContact CB-CD1 3.87Å; W407-T498 WeakPolarHBondContact CH2-OG1 3.23Å; W407-T498 WeakPolarHBondContact CZ3-OG1 3.45Å; W407-W500 HydrophobicContact CB-CD2 3.92Å; W407-W500 HydrophobicContact CB-CE3 3.9Å; W407-W500 HydrophobicContact CB-CH2 3.9Å; W407-W500 HydrophobicContact CB-CZ2 3.87Å; W407-W500 HydrophobicContact CB-CZ3 3.91Å; W407-W500 AromaticContact CD1-CD1 3.94Å; W407-W500 AromaticContact CD1-CE2 3.45Å; W407-W500 VanDerWaalsContact CD1-CE2 3.45Å; W407-W500 AromaticContact CD1-CZ2 3.7Å; W407-W500 AromaticContact CD1-NE1 3.39Å; W407-W500 HydrophobicContact CD2-CB 3.99Å; W407-W500 AromaticContact CD2-CD1 3.56Å; W407-W500 AromaticContact CD2-CD2 3.78Å; W407-W500 HydrophobicContact CD2-CD2 3.78Å; W407-W500 AromaticContact CD2-CE2 3.93Å; W407-W500 HydrophobicContact CD2-CE3 4.48Å; W407-W500 AromaticContact CD2-CG 3.54Å; W407-W500 HydrophobicContact CD2-CG 3.54Å; W407-W500 AromaticContact CD2-NE1 3.81Å; W407-W500 AromaticContact CE2-CD1 3.3Å; W407-W500 AromaticContact CE2-CG 3.79Å; W407-W500 AromaticContact CE2-NE1 3.57Å; W407-W500 HydrophobicContact CE3-CB 3.66Å; W407-W500 HydrophobicContact CE3-CD2 4.22Å; W407-W500 AromaticContact CE3-CG 3.77Å; W407-W500 HydrophobicContact CE3-CG 3.77Å; W407-W500 AromaticContact CG-CD1 3.95Å; W407-W500 AromaticContact CG-CD2 3.63Å; W407-W500 HydrophobicContact CG-CD2 3.63Å; W407-W500 AromaticContact CG-CE2 3.45Å; W407-W500 VanDerWaalsContact CG-CE2 3.45Å; W407-W500 HydrophobicContact CG-CE3 4.14Å; W407-W500 AromaticContact CG-CG 3.94Å; W407-W500 HydrophobicContact CG-CG 3.94Å; W407-W500 HydrophobicContact CG-CH2 4.33Å; W407-W500 AromaticContact CG-CZ2 3.81Å; W407-W500 HydrophobicContact CG-CZ2 3.81Å; W407-W500 HydrophobicContact CG-CZ3 4.47Å; W407-W500 AromaticContact CG-NE1 3.69Å; W407-W500 HydrophobicContact CH2-CB 4.16Å; W407-W500 HydrophobicContact CH2-CG 4.41Å; W407-W500 HydrophobicContact CZ2-CB 4.43Å; W407-W500 AromaticContact CZ2-CD1 3.67Å; W407-W500 HydrophobicContact CZ2-CG 4.21Å; W407-W500 HydrophobicContact CZ3-CB 3.77Å; W407-W500 HydrophobicContact CZ3-CG 4.2Å; W407-W500 AromaticContact NE1-CD1 3.55Å; W407-W500 AromaticContact NE1-CE2 3.86Å; W407-W500 AromaticContact NE1-NE1 3.29Å
408Q98.7Very high98Very high2 Ų218.3 Ų18.31%0.00910%0.095CC..Hα-helixtrans-56.4-38.2172.9-56.9-65.4-36.200111.7I313 L317 D404 A405 V406 Q412 T498I313-Q408 HydrophobicContact CG2-CG 3.57Å; L317-Q408 HydrophobicContact CD1-CB 3.84Å; L317-Q408 HydrophobicContact CD1-CG 4.11Å; D404-Q408 WeakPolarHBondContact O-CG 3.47Å; D404-Q408 PolarHBondContact O-N 3.37Å; D404-Q408 PolarHBondContact OD1-NE2 3.37Å; A405-Q408 PolarHBondContact O-N 2.68Å; V406-Q408 VanDerWaalsContact C-N 3.32Å; V406-Q408 PolarHBondContact O-N 3.06Å; Q408-Q412 WeakPolarHBondContact O-CB 3.27Å; Q408-Q412 VanDerWaalsContact O-CG 3.3Å; Q408-Q412 WeakPolarHBondContact O-CG 3.42Å; Q408-Q412 PolarHBondContact O-N 3.44Å; Q408-Q412 VanDerWaalsContact O-N 3.08Å; Q408-T498 PolarHBondContact NE2-O 3.24Å
409L98.8Very high97.9Very high0 Ų018.2 Ų18.20%010%0.095CC..Hα-helixtrans-69.9-40.8175.3-60.7177000111.8L317 L350 I353 L354 A405 V406 W407 E411 Q412 F413 F417 P490L317-L409 HydrophobicContact CD2-CD1 4.38Å; L317-L409 HydrophobicContact CD2-CD2 3.93Å; L317-L409 HydrophobicContact CD2-CG 4.01Å; L350-L409 HydrophobicContact CD2-CD1 4.14Å; I353-L409 HydrophobicContact CG2-CD1 3.94Å; L354-L409 HydrophobicContact CD2-CD1 3.95Å; L354-L409 HydrophobicContact CD2-CD2 3.87Å; A405-L409 PolarHBondContact O-N 3.08Å; V406-L409 WeakPolarHBondContact O-CA 3.48Å; V406-L409 WeakPolarHBondContact O-CB 3.48Å; V406-L409 PolarHBondContact O-N 3.13Å; W407-L409 PolarHBondContact O-N 3.16Å; L409-E411 VanDerWaalsContact C-N 3.31Å; L409-E411 PolarHBondContact O-N 2.93Å; L409-Q412 PolarHBondContact O-N 3.03Å; L409-F413 HydrophobicContact CB-CD2 4.48Å; L409-F413 HydrophobicContact CD2-CE2 4.23Å; L409-F413 WeakPolarHBondContact O-CB 3.49Å; L409-F413 VanDerWaalsContact O-CD2 3.24Å; L409-F413 WeakPolarHBondContact O-CD2 3.26Å; L409-F413 PolarHBondContact O-N 2.88Å; L409-F417 HydrophobicContact CB-CE2 3.96Å; L409-F417 HydrophobicContact CB-CZ 3.68Å; L409-F417 HydrophobicContact CD1-CZ 4.44Å; L409-P490 HydrophobicContact CD2-CB 3.7Å; L409-P490 HydrophobicContact CD2-CG 4.26Å
410V97.6Very high97.8Very high11 Ų1118.2 Ų18.27%0.06710%0.095CC..Hα-helixtrans-60.8-41.9176.4173.70000110.9V406 W407 F413 P414 F417 F419 L424V406-V410 WeakPolarHBondContact O-CG2 3.1Å; V406-V410 PolarHBondContact O-N 2.69Å; W407-V410 WeakPolarHBondContact O-CB 3.38Å; W407-V410 PolarHBondContact O-N 3.2Å; V410-F413 CarbonylContact O-C 3.47Å; V410-F413 VanDerWaalsContact O-C 3.29Å; V410-F413 PolarHBondContact O-N 3.2Å; V410-P414 WeakPolarHBondContact O-CA 3.45Å; V410-F417 HydrophobicContact CB-CD2 4.39Å; V410-F417 HydrophobicContact CG2-CB 4.12Å; V410-F417 HydrophobicContact CG2-CD1 4.1Å; V410-F417 HydrophobicContact CG2-CD2 3.85Å; V410-F417 HydrophobicContact CG2-CE1 4.49Å; V410-F417 HydrophobicContact CG2-CE2 4.27Å; V410-F417 HydrophobicContact CG2-CG 3.76Å; V410-F419 HydrophobicContact CG2-CD2 4.46Å; V410-F419 HydrophobicContact CG2-CE2 3.87Å; V410-L424 HydrophobicContact CG2-CD1 4.26Å
411E95.7Very high97.6Very high104 Ų10419.1 Ų19.149%0.48610%0.099SC..Hα-helixtrans-65.1-42.6176.2-75-68.9103.600112.5W407 L409 F413W407-E411 HydrophobicContact CD2-CG 3.88Å; W407-E411 HydrophobicContact CE3-CG 4.25Å; W407-E411 HydrophobicContact CH2-CG 3.76Å; W407-E411 HydrophobicContact CZ2-CG 3.35Å; W407-E411 HydrophobicContact CZ3-CG 4.18Å; W407-E411 PolarHBondContact O-N 2.88Å; L409-E411 VanDerWaalsContact C-N 3.31Å; L409-E411 PolarHBondContact O-N 2.93Å; E411-F413 VanDerWaalsContact C-N 3.31Å
412Q97.5Very high97.3Very high40 Ų4020.7 Ų20.719%0.18711%0.105CC..Hα-helixtrans-72.4-25.9178.4-70.7-17621.900112.9Q408 L409 D491 Q496Q408-Q412 WeakPolarHBondContact O-CB 3.27Å; Q408-Q412 VanDerWaalsContact O-CG 3.3Å; Q408-Q412 WeakPolarHBondContact O-CG 3.42Å; Q408-Q412 PolarHBondContact O-N 3.44Å; Q408-Q412 VanDerWaalsContact O-N 3.08Å; L409-Q412 PolarHBondContact O-N 3.03Å; Q412-D491 PolarHBondContact NE2-O 3.24Å; Q412-Q496 PolarHBondContact NE2-O 2.96Å
413F97.4Very high97.2Very high43 Ų4320.8 Ų20.819%0.18911%0.106CC..  trans-131.367.5-174.1-56-71.8000112L409 V410 E411 T415 E416 F417 L488 P490L409-F413 HydrophobicContact CB-CD2 4.48Å; L409-F413 HydrophobicContact CD2-CE2 4.23Å; L409-F413 WeakPolarHBondContact O-CB 3.49Å; L409-F413 VanDerWaalsContact O-CD2 3.24Å; L409-F413 WeakPolarHBondContact O-CD2 3.26Å; L409-F413 PolarHBondContact O-N 2.88Å; V410-F413 CarbonylContact O-C 3.47Å; V410-F413 VanDerWaalsContact O-C 3.29Å; V410-F413 PolarHBondContact O-N 3.2Å; E411-F413 VanDerWaalsContact C-N 3.31Å; F413-T415 PolarHBondContact O-N 3.43Å; F413-E416 HydrophobicContact CB-CB 3.83Å; F413-E416 HydrophobicContact CB-CG 3.75Å; F413-E416 HydrophobicContact CG-CG 4.46Å; F413-E416 PolarHBondContact O-N 2.93Å; F413-E416 VanDerWaalsContact O-N 3.09Å; F413-F417 HydrophobicContact CB-CE2 4.16Å; F413-L488 HydrophobicContact CB-CD1 4.45Å; F413-L488 HydrophobicContact CD1-CD2 3.8Å; F413-L488 HydrophobicContact CD2-CB 4.49Å; F413-L488 HydrophobicContact CD2-CD1 3.84Å; F413-L488 HydrophobicContact CD2-CD2 4.33Å; F413-L488 HydrophobicContact CD2-CG 4.42Å; F413-L488 HydrophobicContact CE1-CD2 3.99Å; F413-L488 HydrophobicContact CE2-CB 4.11Å; F413-L488 HydrophobicContact CE2-CD1 4.28Å; F413-L488 HydrophobicContact CG-CD1 4.09Å; F413-L488 HydrophobicContact CG-CD2 3.99Å; F413-L488 HydrophobicContact CZ-CB 4.2Å; F413-L488 HydrophobicContact CZ-CD2 4.36Å; F413-P490 HydrophobicContact CE2-CB 4.42Å
414P94.1Very high97.1Very high66 Ų6620.8 Ų20.843%0.42911%0.106SC..THydrogen-bonded Turntrans-64.1-14.4-167.324.2-35.5000115.4V410 N476 L478V410-P414 WeakPolarHBondContact O-CA 3.45Å; P414-N476 PolarHBondContact O-ND2 2.84Å; P414-L478 HydrophobicContact CB-CD1 4.42Å
415T95.9Very high96.9Very high63 Ų6321.4 Ų21.439%0.38711%0.109SC..THydrogen-bonded Turntrans-106.8-5.6179.660.20000114F413 L478F413-T415 PolarHBondContact O-N 3.43Å; T415-L478 HydrophobicContact CG2-CB 4.26Å
416E98Very high96.8Very high11 Ų1121.8 Ų21.85%0.05111%0.111CC..THydrogen-bonded Turntrans-90.7-14.7-169-70.1-74.3162.900113.8R360 F413 V484 S485 L488R360-E416 VanDerWaalsContact CB-O 3.25Å; R360-E416 WeakPolarHBondContact CB-O 3.33Å; R360-E416 WeakPolarHBondContact CD-O 3.38Å; R360-E416 IonicContact NH1-OE2 3.43Å; R360-E416 PolarHBondContact NH1-OE2 3.41Å; F413-E416 HydrophobicContact CB-CB 3.83Å; F413-E416 HydrophobicContact CB-CG 3.75Å; F413-E416 HydrophobicContact CG-CG 4.46Å; F413-E416 PolarHBondContact O-N 2.93Å; F413-E416 VanDerWaalsContact O-N 3.09Å; E416-V484 WeakPolarHBondContact OE2-CA 3.2Å; E416-V484 WeakPolarHBondContact OE2-CB 3.45Å; E416-S485 VanDerWaalsContact CD-N 3.28Å; E416-S485 WeakPolarHBondContact OE1-CB 3.18Å; E416-S485 PolarHBondContact OE1-N 3.29Å; E416-S485 PolarHBondContact OE1-OG 3.04Å; E416-S485 PolarHBondContact OE2-N 3.36Å; E416-L488 HydrophobicContact CB-CD1 4.36Å; E416-L488 HydrophobicContact CB-CD2 4.48Å; E416-L488 HydrophobicContact CG-CD2 3.87Å
417F98.5Very high96.7Very high0 Ų021.8 Ų21.80%011%0.111CC..  trans-114.7129.8-174.7-67-91.6000111.7I353 R360 L409 V410 F413 F419 N476 F479 L488I353-F417 HydrophobicContact CG2-CE1 3.65Å; I353-F417 HydrophobicContact CG2-CZ 3.85Å; R360-F417 HydrophobicContact CB-CD1 3.72Å; R360-F417 HydrophobicContact CB-CE1 4.02Å; R360-F417 HydrophobicContact CB-CG 4.3Å; R360-F417 HydrophobicContact CG-CD1 4Å; R360-F417 HydrophobicContact CG-CE1 3.76Å; R360-F417 HydrophobicContact CG-CZ 4.26Å; L409-F417 HydrophobicContact CB-CE2 3.96Å; L409-F417 HydrophobicContact CB-CZ 3.68Å; L409-F417 HydrophobicContact CD1-CZ 4.44Å; V410-F417 HydrophobicContact CB-CD2 4.39Å; V410-F417 HydrophobicContact CG2-CB 4.12Å; V410-F417 HydrophobicContact CG2-CD1 4.1Å; V410-F417 HydrophobicContact CG2-CD2 3.85Å; V410-F417 HydrophobicContact CG2-CE1 4.49Å; V410-F417 HydrophobicContact CG2-CE2 4.27Å; V410-F417 HydrophobicContact CG2-CG 3.76Å; F413-F417 HydrophobicContact CB-CE2 4.16Å; F417-F419 VanDerWaalsContact C-N 3.31Å; F417-F419 HydrophobicContact CB-CE2 4.4Å; F417-F419 HydrophobicContact CB-CZ 4.48Å; F417-F419 AromaticContact CD1-CE1 3.89Å; F417-F419 HydrophobicContact CD1-CE1 3.89Å; F417-F419 AromaticContact CD1-CE2 3.87Å; F417-F419 HydrophobicContact CD1-CE2 3.87Å; F417-F419 AromaticContact CD1-CZ 3.38Å; F417-F419 HydrophobicContact CD1-CZ 3.38Å; F417-F419 AromaticContact CE1-CZ 3.99Å; F417-F419 HydrophobicContact CE1-CZ 3.99Å; F417-F419 HydrophobicContact CG-CE2 4.44Å; F417-F419 HydrophobicContact CG-CZ 4.32Å; F417-N476 WeakPolarHBondContact O-CB 3.04Å; F417-N476 PolarHBondContact O-ND2 3.44Å; F417-F479 WeakPolarHBondContact O-CB 3.5Å; F417-F479 WeakPolarHBondContact O-CD2 3.46Å; F417-L488 HydrophobicContact CE2-CD1 4.11Å; F417-L488 HydrophobicContact CZ-CD1 4.14Å
418E98.1Very high96.6Very high29 Ų2921.3 Ų21.314%0.13611%0.109CC..SBendtrans-71.2-28.9177.9-172.8-179.1-153.400112.2R360 T361 I362 R475 N476 F479R360-E418 PolarHBondContact O-N 3.19Å; T361-E418 VanDerWaalsContact CA-OE2 3.31Å; T361-E418 WeakPolarHBondContact CA-OE2 3.31Å; T361-E418 VanDerWaalsContact CB-OE2 3.25Å; T361-E418 WeakPolarHBondContact CB-OE2 3.38Å; I362-E418 HydrophobicContact CD1-CG 4.14Å; I362-E418 HydrophobicContact CG1-CB 4.41Å; I362-E418 HydrophobicContact CG1-CG 4.14Å; I362-E418 PolarHBondContact N-OE2 3.28Å; E418-R475 HydrophobicContact CG-CG 4.41Å; E418-R475 CarbonylContact O-C 3.07Å; E418-R475 WeakPolarHBondContact O-CA 3.26Å; E418-R475 WeakPolarHBondContact O-CG 3.38Å; E418-R475 IonicContact OE1-CZ 2.86Å; E418-R475 IonicContact OE1-NH1 2.83Å; E418-R475 PolarHBondContact OE1-NH1 3.47Å; E418-R475 IonicContact OE1-NH2 2.62Å; E418-N476 PolarHBondContact O-N 2.93Å; E418-F479 VanDerWaalsContact CA-CG 3.44Å; E418-F479 HydrophobicContact CB-CD1 3.72Å; E418-F479 HydrophobicContact CB-CD2 4.24Å; E418-F479 HydrophobicContact CB-CE1 3.67Å; E418-F479 HydrophobicContact CB-CE2 4.18Å; E418-F479 HydrophobicContact CB-CG 4Å; E418-F479 HydrophobicContact CB-CZ 3.91Å; E418-F479 HydrophobicContact CG-CD1 3.75Å; E418-F479 HydrophobicContact CG-CE1 3.8Å; E418-F479 HydrophobicContact CG-CG 4.42Å
419F98.1Very high96.4Very high0 Ų024 Ų240%012%0.122CC..BIsolated β-bridgetrans-92.1148.4175.456.1-98.3000111I362 F365 V406 V410 F417 Y423 L424 L474I362-F419 HydrophobicContact CG1-CB 3.88Å; F365-F419 HydrophobicContact CB-CD1 4.16Å; F365-F419 HydrophobicContact CB-CE1 3.64Å; F365-F419 HydrophobicContact CB-CZ 4.44Å; F365-F419 HydrophobicContact CD1-CD1 4.47Å; F365-F419 HydrophobicContact CD1-CE1 4.05Å; F365-F419 HydrophobicContact CD1-CZ 4.23Å; F365-F419 HydrophobicContact CD2-CE1 4Å; F365-F419 AromaticContact CD2-CZ 3.98Å; F365-F419 HydrophobicContact CD2-CZ 3.98Å; F365-F419 HydrophobicContact CE1-CZ 4.46Å; F365-F419 HydrophobicContact CE2-CZ 4.25Å; F365-F419 HydrophobicContact CG-CD1 4.36Å; F365-F419 AromaticContact CG-CE1 3.64Å; F365-F419 HydrophobicContact CG-CE1 3.64Å; F365-F419 AromaticContact CG-CZ 3.97Å; F365-F419 HydrophobicContact CG-CZ 3.97Å; F365-F419 HydrophobicContact CZ-CZ 4.48Å; V406-F419 HydrophobicContact CG1-CE2 3.88Å; V406-F419 HydrophobicContact CG1-CZ 3.94Å; V410-F419 HydrophobicContact CG2-CD2 4.46Å; V410-F419 HydrophobicContact CG2-CE2 3.87Å; F417-F419 VanDerWaalsContact C-N 3.31Å; F417-F419 HydrophobicContact CB-CE2 4.4Å; F417-F419 HydrophobicContact CB-CZ 4.48Å; F417-F419 AromaticContact CD1-CE1 3.89Å; F417-F419 HydrophobicContact CD1-CE1 3.89Å; F417-F419 AromaticContact CD1-CE2 3.87Å; F417-F419 HydrophobicContact CD1-CE2 3.87Å; F417-F419 AromaticContact CD1-CZ 3.38Å; F417-F419 HydrophobicContact CD1-CZ 3.38Å; F417-F419 AromaticContact CE1-CZ 3.99Å; F417-F419 HydrophobicContact CE1-CZ 3.99Å; F417-F419 HydrophobicContact CG-CE2 4.44Å; F417-F419 HydrophobicContact CG-CZ 4.32Å; F419-Y423 HydrophobicContact CB-CD1 3.75Å; F419-Y423 HydrophobicContact CB-CD2 3.99Å; F419-Y423 HydrophobicContact CB-CE1 4.43Å; F419-Y423 HydrophobicContact CB-CG 3.54Å; F419-Y423 HydrophobicContact CD2-CD1 4.14Å; F419-Y423 AromaticContact CG-CD1 3.95Å; F419-Y423 HydrophobicContact CG-CD1 3.95Å; F419-Y423 HydrophobicContact CG-CE1 4.46Å; F419-Y423 HydrophobicContact CG-CG 4.25Å; F419-L424 HydrophobicContact CD2-CD2 4.06Å; F419-L424 HydrophobicContact CD2-CG 4.15Å; F419-L424 HydrophobicContact CE2-CD1 4.27Å; F419-L424 HydrophobicContact CE2-CD2 3.72Å; F419-L424 HydrophobicContact CE2-CG 4.1Å; F419-L474 WeakPolarHBondContact CA-O 3.37Å
420N95.4Very high96.2Very high3 Ų324.6 Ų24.62%0.01612%0.124CC..  trans-98.4-179.817764.128.7000112.1R422 Y423 E473 L474 R475 N476 L517N420-R422 VanDerWaalsContact C-N 3.26Å; N420-R422 PolarHBondContact O-N 3.27Å; N420-R422 WeakPolarHBondContact OD1-CA 3.38Å; N420-R422 VanDerWaalsContact OD1-CB 3.25Å; N420-R422 WeakPolarHBondContact OD1-CB 3.32Å; N420-R422 PolarHBondContact OD1-N 3.38Å; N420-Y423 VanDerWaalsContact O-CB 3.29Å; N420-Y423 WeakPolarHBondContact O-CB 3.49Å; N420-Y423 PolarHBondContact O-N 3.07Å; N420-Y423 VanDerWaalsContact O-N 3.14Å; N420-Y423 PolarHBondContact OD1-N 2.94Å; N420-E473 PolarHBondContact ND2-O 3.49Å; N420-L474 PolarHBondContact N-O 3.03Å; N420-L474 VanDerWaalsContact ND2-C 3.28Å; N420-L474 PolarHBondContact ND2-O 2.93Å; N420-L474 PolarHBondContact OD1-O 3.03Å; N420-R475 PolarHBondContact ND2-O 2.84Å; N420-N476 HydrophobicContact CB-CB 4.17Å; N420-L517 HydrophobicContact CB-CD1 4.16Å; N420-L517 HydrophobicContact CB-CD2 4.13Å
421E93.8Very high96.2Very high19 Ų1924.1 Ų24.19%0.08912%0.122CC..Hα-helixtrans-56.2-37.8175.4178.5-176.6-144.300112.9W407 Y423 L424 I425 W500 S502 L515 L517W407-E421 PolarHBondContact NE1-OE1 3.28Å; E421-Y423 VanDerWaalsContact C-N 3.27Å; E421-Y423 PolarHBondContact O-N 3.24Å; E421-L424 PolarHBondContact O-N 2.86Å; E421-L424 VanDerWaalsContact O-N 3.16Å; E421-I425 HydrophobicContact CG-CD1 3.77Å; E421-I425 HydrophobicContact CG-CG1 4.27Å; E421-I425 WeakPolarHBondContact O-CB 3.5Å; E421-I425 WeakPolarHBondContact O-CG1 3.42Å; E421-I425 PolarHBondContact O-N 3.22Å; E421-W500 HydrophobicContact CG-CZ2 4.03Å; E421-W500 PolarHBondContact OE1-NE1 2.94Å; E421-S502 WeakPolarHBondContact OE1-CB 3.5Å; E421-S502 PolarHBondContact OE1-OG 2.98Å; E421-S502 PolarHBondContact OE2-OG 2.72Å; E421-L515 WeakPolarHBondContact OE2-CD2 3.29Å; E421-L517 HydrophobicContact CB-CD2 4.43Å
422R92.3Very high96.1Very high34 Ų3419.9 Ų19.913%0.12810%0.101CC..Hα-helixtrans-61.1-36.8178.1-177178.6-69.5119.66.1111.7N420 L424 I425 T426 E473 L474 N518N420-R422 VanDerWaalsContact C-N 3.26Å; N420-R422 PolarHBondContact O-N 3.27Å; N420-R422 WeakPolarHBondContact OD1-CA 3.38Å; N420-R422 VanDerWaalsContact OD1-CB 3.25Å; N420-R422 WeakPolarHBondContact OD1-CB 3.32Å; N420-R422 PolarHBondContact OD1-N 3.38Å; R422-L424 PolarHBondContact O-N 3.05Å; R422-I425 PolarHBondContact O-N 2.97Å; R422-T426 WeakPolarHBondContact O-CB 3.34Å; R422-T426 PolarHBondContact O-N 2.96Å; R422-T426 PolarHBondContact O-OG1 3.32Å; R422-E473 PolarHBondContact NH1-O 3.1Å; R422-L474 HydrophobicContact CB-CD2 4.23Å; R422-L474 HydrophobicContact CG-CD2 3.68Å; R422-N518 PolarHBondContact NH2-OD1 3.18Å
423Y97.3Very high95.9Very high2 Ų218.3 Ų18.31%0.00810%0.095CC..Hα-helixtrans-57.7-47.8174.7-177.9-83.2000112I362 F365 Q366 F419 N420 E421 T426 L427 M467 L474I362-Y423 HydrophobicContact CG1-CD2 4.45Å; I362-Y423 HydrophobicContact CG1-CE2 4.3Å; I362-Y423 HydrophobicContact CG2-CE2 3.91Å; F365-Y423 AromaticContact CD1-CE1 3.67Å; F365-Y423 HydrophobicContact CD1-CE1 3.67Å; F365-Y423 AromaticContact CE1-CE1 3.97Å; F365-Y423 HydrophobicContact CE1-CE1 3.97Å; Q366-Y423 WeakPolarHBondContact CG-OH 3.39Å; Q366-Y423 PolarHBondContact NE2-OH 3.02Å; F419-Y423 HydrophobicContact CB-CD1 3.75Å; F419-Y423 HydrophobicContact CB-CD2 3.99Å; F419-Y423 HydrophobicContact CB-CE1 4.43Å; F419-Y423 HydrophobicContact CB-CG 3.54Å; F419-Y423 HydrophobicContact CD2-CD1 4.14Å; F419-Y423 AromaticContact CG-CD1 3.95Å; F419-Y423 HydrophobicContact CG-CD1 3.95Å; F419-Y423 HydrophobicContact CG-CE1 4.46Å; F419-Y423 HydrophobicContact CG-CG 4.25Å; N420-Y423 VanDerWaalsContact O-CB 3.29Å; N420-Y423 WeakPolarHBondContact O-CB 3.49Å; N420-Y423 PolarHBondContact O-N 3.07Å; N420-Y423 VanDerWaalsContact O-N 3.14Å; N420-Y423 PolarHBondContact OD1-N 2.94Å; E421-Y423 VanDerWaalsContact C-N 3.27Å; E421-Y423 PolarHBondContact O-N 3.24Å; Y423-T426 PolarHBondContact O-N 3.5Å; Y423-L427 HydrophobicContact CD1-CD1 4.03Å; Y423-L427 HydrophobicContact CD1-CG 4.43Å; Y423-L427 HydrophobicContact CE1-CD1 3.49Å; Y423-L427 VanDerWaalsContact CE1-CD1 3.49Å; Y423-L427 HydrophobicContact CE1-CG 4.01Å; Y423-L427 PolarHBondContact O-N 3.06Å; Y423-M467 HydrophobicContact CD1-CE 4.21Å; Y423-M467 HydrophobicContact CD2-CE 3.35Å; Y423-M467 HydrophobicContact CE1-CE 4.12Å; Y423-M467 HydrophobicContact CE2-CE 3.25Å; Y423-M467 HydrophobicContact CE2-SD 4.31Å; Y423-M467 HydrophobicContact CG-CE 3.81Å; Y423-L474 HydrophobicContact CD2-CB 3.94Å; Y423-L474 HydrophobicContact CD2-CD1 3.96Å
424L97.9Very high95.7Very high0 Ų016.3 Ų16.30%09%0.086CC..Hα-helixtrans-67.4-39.1179.7-58.9174000111.5F365 L403 V406 W407 V410 F419 E421 R422 L427 Q428 W500F365-L424 HydrophobicContact CE1-CD2 3.8Å; F365-L424 HydrophobicContact CZ-CD2 3.92Å; L403-L424 HydrophobicContact CD2-CD2 4.04Å; V406-L424 HydrophobicContact CB-CD1 4.42Å; V406-L424 HydrophobicContact CB-CD2 4.42Å; V406-L424 HydrophobicContact CG1-CD1 4.02Å; V406-L424 HydrophobicContact CG1-CD2 3.87Å; W407-L424 HydrophobicContact CB-CD1 3.87Å; V410-L424 HydrophobicContact CG2-CD1 4.26Å; F419-L424 HydrophobicContact CD2-CD2 4.06Å; F419-L424 HydrophobicContact CD2-CG 4.15Å; F419-L424 HydrophobicContact CE2-CD1 4.27Å; F419-L424 HydrophobicContact CE2-CD2 3.72Å; F419-L424 HydrophobicContact CE2-CG 4.1Å; E421-L424 PolarHBondContact O-N 2.86Å; E421-L424 VanDerWaalsContact O-N 3.16Å; R422-L424 PolarHBondContact O-N 3.05Å; L424-L427 WeakPolarHBondContact O-CB 3.45Å; L424-L427 PolarHBondContact O-N 2.9Å; L424-Q428 PolarHBondContact O-N 3Å; L424-W500 HydrophobicContact CB-CH2 3.64Å; L424-W500 HydrophobicContact CB-CZ2 4.02Å; L424-W500 HydrophobicContact CD1-CH2 4.31Å
425I94.5Very high95.7Very high13 Ų1315.2 Ų15.27%0.0678%0.075CC..Hα-helixtrans-63.9-41.9174.6-73.7179.9000111.1E421 R422 L427 Q428 E429 W500 L503 R506E421-I425 HydrophobicContact CG-CD1 3.77Å; E421-I425 HydrophobicContact CG-CG1 4.27Å; E421-I425 WeakPolarHBondContact O-CB 3.5Å; E421-I425 WeakPolarHBondContact O-CG1 3.42Å; E421-I425 PolarHBondContact O-N 3.22Å; R422-I425 PolarHBondContact O-N 2.97Å; I425-L427 VanDerWaalsContact C-N 3.35Å; I425-Q428 PolarHBondContact O-N 3.11Å; I425-E429 WeakPolarHBondContact O-CB 3.38Å; I425-E429 PolarHBondContact O-N 2.89Å; I425-W500 HydrophobicContact CD1-CZ2 4.26Å; I425-W500 HydrophobicContact CG1-CH2 4.27Å; I425-W500 HydrophobicContact CG1-CZ2 3.54Å; I425-L503 HydrophobicContact CG1-CD1 4.46Å; I425-R506 VanDerWaalsContact CG2-NE 3.31Å
426T95.2Very high95.7Very high8 Ų812.5 Ų12.55%0.0496%0.058CC..Hα-helixtrans-64.5-38175.8-66.40000111.7R422 Y423 E429 H430 M467R422-T426 WeakPolarHBondContact O-CB 3.34Å; R422-T426 PolarHBondContact O-N 2.96Å; R422-T426 PolarHBondContact O-OG1 3.32Å; Y423-T426 PolarHBondContact O-N 3.5Å; T426-E429 PolarHBondContact O-N 3.2Å; T426-H430 WeakPolarHBondContact O-CB 3.4Å; T426-H430 PolarHBondContact O-CD2 3.45Å; T426-H430 PolarHBondContact O-N 3.09Å; T426-M467 HydrophobicContact CG2-CE 3.91Å; T426-M467 HydrophobicContact CG2-CG 4.22Å; T426-M467 HydrophobicContact CG2-SD 4.32Å
427L97.8Very high95.5Very high0 Ų012 Ų120%06%0.056CC..Hα-helixtrans-59.5-48.6170.3-82.7178000111.7F365 I369 L403 Y423 L424 I425 E429 H430 L431 F439 L463 W464 M467F365-L427 HydrophobicContact CD1-CD1 4.3Å; F365-L427 HydrophobicContact CE1-CD1 3.61Å; I369-L427 HydrophobicContact CD1-CD1 3.97Å; L403-L427 HydrophobicContact CD1-CB 3.99Å; L403-L427 HydrophobicContact CD2-CB 4.42Å; L403-L427 HydrophobicContact CD2-CD1 3.93Å; Y423-L427 HydrophobicContact CD1-CD1 4.03Å; Y423-L427 HydrophobicContact CD1-CG 4.43Å; Y423-L427 HydrophobicContact CE1-CD1 3.49Å; Y423-L427 VanDerWaalsContact CE1-CD1 3.49Å; Y423-L427 HydrophobicContact CE1-CG 4.01Å; Y423-L427 PolarHBondContact O-N 3.06Å; L424-L427 WeakPolarHBondContact O-CB 3.45Å; L424-L427 PolarHBondContact O-N 2.9Å; I425-L427 VanDerWaalsContact C-N 3.35Å; L427-E429 VanDerWaalsContact C-N 3.3Å; L427-E429 PolarHBondContact O-N 2.78Å; L427-H430 PolarHBondContact O-N 3.17Å; L427-L431 WeakPolarHBondContact O-CB 3.42Å; L427-L431 PolarHBondContact O-N 2.99Å; L427-F439 HydrophobicContact CD2-CE2 4.13Å; L427-F439 HydrophobicContact CD2-CZ 4.07Å; L427-L463 HydrophobicContact CD2-CD2 3.85Å; L427-W464 HydrophobicContact CD2-CH2 3.8Å; L427-W464 HydrophobicContact CD2-CZ3 3.57Å; L427-M467 HydrophobicContact CD2-CE 4.5Å; L427-M467 HydrophobicContact CD2-SD 4.04Å; L427-M467 HydrophobicContact CG-CE 4.21Å; L427-M467 HydrophobicContact CG-SD 4.38Å
428Q96.5Very high95.4Very high0 Ų012 Ų120%06%0.056CC..Hα-helixtrans-63.2-38.2179.6-168.5-81.7-1600111.7T400 L403 L424 I425 L431 Y432 L503T400-Q428 HydrophobicContact CG2-CG 3.96Å; L403-Q428 HydrophobicContact CD1-CB 3.8Å; L403-Q428 HydrophobicContact CD1-CG 4.46Å; L424-Q428 PolarHBondContact O-N 3Å; I425-Q428 PolarHBondContact O-N 3.11Å; Q428-L431 WeakPolarHBondContact O-CB 3.31Å; Q428-Y432 HydrophobicContact CG-CE2 4.43Å; Q428-Y432 VanDerWaalsContact NE2-CE2 3.31Å; Q428-Y432 WeakPolarHBondContact O-CD2 3.29Å; Q428-L503 HydrophobicContact CB-CD1 4.28Å; Q428-L503 HydrophobicContact CG-CD1 3.96Å; Q428-L503 HydrophobicContact CG-CD2 4.46Å
429E93.4Very high95.3Very high59 Ų5910.9 Ų10.928%0.2765%0.051SC..Hα-helixtrans-64.9-48.9176.9-176172.8168.200111.9Q53 I425 T426 L427 L431 Y432 S433 R506Q53-E429 PolarHBondContact NE2-O 3.47Å; Q53-E429 VanDerWaalsContact NE2-O 3.17Å; I425-E429 WeakPolarHBondContact O-CB 3.38Å; I425-E429 PolarHBondContact O-N 2.89Å; T426-E429 PolarHBondContact O-N 3.2Å; L427-E429 VanDerWaalsContact C-N 3.3Å; L427-E429 PolarHBondContact O-N 2.78Å; E429-L431 VanDerWaalsContact C-N 3.32Å; E429-L431 PolarHBondContact O-N 3.36Å; E429-Y432 PolarHBondContact O-N 3.41Å; E429-S433 PolarHBondContact O-N 3.12Å; E429-R506 IonicContact OE2-CZ 3.24Å; E429-R506 IonicContact OE2-NH1 3.73Å; E429-R506 PolarHBondContact OE2-NH1 2.86Å; E429-R506 IonicContact OE2-NH2 3.82Å; E429-R506 PolarHBondContact OE2-NH2 3Å
430H95.6Very high95.1Very high11 Ų1111 Ų115%0.0515%0.051CC..Hα-helixtrans-79.9-15.5-176.3-71.7-53.3000114.2T426 L427 Y432 S433 F436 L463 Y466T426-H430 WeakPolarHBondContact O-CB 3.4Å; T426-H430 PolarHBondContact O-CD2 3.45Å; T426-H430 PolarHBondContact O-N 3.09Å; L427-H430 PolarHBondContact O-N 3.17Å; H430-Y432 VanDerWaalsContact C-N 3.25Å; H430-Y432 PolarHBondContact O-N 3.09Å; H430-S433 VanDerWaalsContact CA-OG 3.31Å; H430-S433 WeakPolarHBondContact CA-OG 3.2Å; H430-S433 PolarHBondContact ND1-OG 3.13Å; H430-S433 VanDerWaalsContact ND1-OG 3.12Å; H430-S433 PolarHBondContact O-OG 3.49Å; H430-F436 HydrophobicContact CB-CD2 4.08Å; H430-F436 HydrophobicContact CB-CE2 4.33Å; H430-F436 AromaticContact CE1-CE2 3.66Å; H430-F436 AromaticContact CG-CD2 3.93Å; H430-F436 AromaticContact CG-CE2 3.68Å; H430-F436 AromaticContact ND1-CD2 3.88Å; H430-F436 AromaticContact ND1-CE2 3.45Å; H430-F436 WeakPolarHBondContact ND1-CE2 3.12Å; H430-F436 AromaticContact NE2-CE2 3.99Å; H430-L463 HydrophobicContact CB-CD1 3.6Å; H430-L463 HydrophobicContact CB-CD2 3.83Å; H430-L463 HydrophobicContact CB-CG 4.36Å; H430-Y466 AromaticContact CD2-CE1 3.96Å; H430-Y466 AromaticContact NE2-CE1 3.38Å; H430-Y466 WeakPolarHBondContact NE2-CE1 3.44Å; H430-Y466 AromaticContact NE2-CZ 3.94Å
431L96.3Very high95.1Very high1 Ų111 Ų111%0.0055%0.052CC..Hα-helixtrans-51.5-47.2161.8-178.168.7000110.4F380 H386 F399 L427 Q428 E429 F439F380-L431 HydrophobicContact CD1-CD1 3.44Å; F380-L431 VanDerWaalsContact CD1-CD1 3.44Å; F380-L431 HydrophobicContact CE1-CD1 3.56Å; H386-L431 PolarHBondContact CE1-O 3.47Å; F399-L431 HydrophobicContact CB-CD2 4.16Å; F399-L431 HydrophobicContact CD1-CD1 3.99Å; F399-L431 HydrophobicContact CD1-CD2 4.01Å; L427-L431 WeakPolarHBondContact O-CB 3.42Å; L427-L431 PolarHBondContact O-N 2.99Å; Q428-L431 WeakPolarHBondContact O-CB 3.31Å; E429-L431 VanDerWaalsContact C-N 3.32Å; E429-L431 PolarHBondContact O-N 3.36Å; L431-F439 HydrophobicContact CD1-CB 4.11Å; L431-F439 HydrophobicContact CD1-CD1 4.49Å; L431-F439 HydrophobicContact CD1-CD2 4.25Å; L431-F439 HydrophobicContact CD1-CG 4.05Å
432Y94.6Very high95.1Very high15 Ų1511.1 Ų11.16%0.0595%0.053CC..Hα-helixtrans-96.8-14.8-175.5-61.4-73000114.5K74 T75 C384 T400 Q428 E429 H430 C434K74-Y432 HydrophobicContact CB-CD1 3.61Å; K74-Y432 HydrophobicContact CB-CD2 4.28Å; K74-Y432 HydrophobicContact CB-CE1 4.19Å; K74-Y432 HydrophobicContact CB-CG 3.65Å; K74-Y432 HydrophobicContact CD-CD1 3.72Å; K74-Y432 HydrophobicContact CD-CG 4.31Å; K74-Y432 HydrophobicContact CG-CD1 4.19Å; T75-Y432 HydrophobicContact CG2-CD2 3.84Å; T75-Y432 HydrophobicContact CG2-CG 4.38Å; C384-Y432 HydrophobicContact CB-CD1 3.88Å; C384-Y432 HydrophobicContact CB-CE1 3.66Å; T400-Y432 PolarHBondContact OG1-OH 3.35Å; T400-Y432 VanDerWaalsContact OG1-OH 3.13Å; Q428-Y432 HydrophobicContact CG-CE2 4.43Å; Q428-Y432 VanDerWaalsContact NE2-CE2 3.31Å; Q428-Y432 WeakPolarHBondContact O-CD2 3.29Å; E429-Y432 PolarHBondContact O-N 3.41Å; H430-Y432 VanDerWaalsContact C-N 3.25Å; H430-Y432 PolarHBondContact O-N 3.09Å; Y432-C434 PolarHBondContact O-N 3.3Å
433S93.1Very high95.1Very high8 Ų810 Ų106%0.0565%0.05CC..Hα-helixtrans-65.4-22.3-17872.50000113.9C52 E429 H430 Q435C52-S433 PolarHBondContact SG-O 3.25Å; E429-S433 PolarHBondContact O-N 3.12Å; H430-S433 VanDerWaalsContact CA-OG 3.31Å; H430-S433 WeakPolarHBondContact CA-OG 3.2Å; H430-S433 PolarHBondContact ND1-OG 3.13Å; H430-S433 VanDerWaalsContact ND1-OG 3.12Å; H430-S433 PolarHBondContact O-OG 3.49Å; S433-Q435 PolarHBondContact O-N 3.32Å; S433-Q435 WeakPolarHBondContact OG-CB 3.49Å; S433-Q435 PolarHBondContact OG-N 2.93Å
434C94.1Very high94.9Very high1 Ų110.8 Ų10.81%0.0075%0.054CC..  trans47.924.1-171.3-56.50000113.6C52 L108 A110 H386 Y432 L440C52-C434 HydrophobicContact CB-CB 4.17Å; L108-C434 HydrophobicContact CB-CB 4.11Å; L108-C434 HydrophobicContact CD1-CB 4.29Å; L108-C434 HydrophobicContact CD2-CB 4.01Å; L108-C434 HydrophobicContact CG-CB 4.37Å; A110-C434 WeakPolarHBondContact CA-O 3.48Å; A110-C434 VanDerWaalsContact CB-O 3.23Å; A110-C434 WeakPolarHBondContact CB-O 3.44Å; A110-C434 PolarHBondContact N-O 2.85Å; H386-C434 PolarHBondContact ND1-SG 2.69Å; Y432-C434 PolarHBondContact O-N 3.3Å; C434-L440 HydrophobicContact CB-CD2 3.99Å
435Q93.3Very high94.6Very high43 Ų4312.8 Ų12.820%0.2016%0.063CC..  trans-85-20.9-177.4-176.7-179-14.700111.9A110 Y113 S433A110-Q435 WeakPolarHBondContact CA-O 3.46Å; Y113-Q435 HydrophobicContact CD1-CG 3.99Å; Y113-Q435 HydrophobicContact CD2-CG 3.76Å; Y113-Q435 HydrophobicContact CE1-CG 4.12Å; Y113-Q435 HydrophobicContact CE2-CG 3.93Å; Y113-Q435 HydrophobicContact CG-CG 3.83Å; Y113-Q435 PolarHBondContact OH-NE2 3.33Å; S433-Q435 PolarHBondContact O-N 3.32Å; S433-Q435 WeakPolarHBondContact OG-CB 3.49Å; S433-Q435 PolarHBondContact OG-N 2.93Å
436F95.3Very high94.5Very high5 Ų514.7 Ų14.72%0.0227%0.071CC..SBendtrans-124.3149.6-178.4-57-73.6000110Y113 H430 T438 L440 Y461 L463 Y466Y113-F436 HydrophobicContact CD1-CE1 4.49Å; Y113-F436 AromaticContact CE1-CE1 3.95Å; Y113-F436 HydrophobicContact CE1-CE1 3.95Å; Y113-F436 HydrophobicContact CE1-CZ 4.44Å; H430-F436 HydrophobicContact CB-CD2 4.08Å; H430-F436 HydrophobicContact CB-CE2 4.33Å; H430-F436 AromaticContact CE1-CE2 3.66Å; H430-F436 AromaticContact CG-CD2 3.93Å; H430-F436 AromaticContact CG-CE2 3.68Å; H430-F436 AromaticContact ND1-CD2 3.88Å; H430-F436 AromaticContact ND1-CE2 3.45Å; H430-F436 WeakPolarHBondContact ND1-CE2 3.12Å; H430-F436 AromaticContact NE2-CE2 3.99Å; F436-T438 VanDerWaalsContact C-N 3.27Å; F436-T438 PolarHBondContact O-N 2.97Å; F436-L440 WeakPolarHBondContact O-CG 3.28Å; F436-Y461 CarbonylContact C-O 3.55Å; F436-Y461 WeakPolarHBondContact CA-O 3.36Å; F436-Y461 WeakPolarHBondContact CB-O 3.41Å; F436-L463 HydrophobicContact CB-CB 3.92Å; F436-L463 HydrophobicContact CD2-CB 4.13Å; F436-L463 HydrophobicContact CD2-CD1 3.57Å; F436-L463 HydrophobicContact CD2-CG 4.41Å; F436-L463 HydrophobicContact CE2-CD1 3.68Å; F436-L463 HydrophobicContact CG-CB 3.99Å; F436-L463 HydrophobicContact CG-CD1 4.23Å; F436-L463 HydrophobicContact CZ-CD1 4.44Å; F436-Y466 HydrophobicContact CE1-CD2 4.15Å; F436-Y466 AromaticContact CE1-CG 3.86Å; F436-Y466 HydrophobicContact CE1-CG 3.86Å; F436-Y466 HydrophobicContact CE2-CD1 4.02Å; F436-Y466 HydrophobicContact CE2-CE1 4.45Å; F436-Y466 HydrophobicContact CE2-CG 4.1Å; F436-Y466 AromaticContact CZ-CD1 3.71Å; F436-Y466 HydrophobicContact CZ-CD1 3.71Å; F436-Y466 AromaticContact CZ-CD2 3.61Å; F436-Y466 HydrophobicContact CZ-CD2 3.61Å; F436-Y466 HydrophobicContact CZ-CE1 4.27Å; F436-Y466 HydrophobicContact CZ-CE2 4.18Å; F436-Y466 AromaticContact CZ-CG 3.33Å; F436-Y466 HydrophobicContact CZ-CG 3.33Å
437G94.7Very high94.2Very high0 Ų015.7 Ų15.70%07%0.074CC..G310 helixtrans-70.2-20.1-178.100000114.6F439 L440 T460 Y461G437-F439 VanDerWaalsContact C-N 3.3Å; G437-F439 PolarHBondContact O-N 3.48Å; G437-F439 VanDerWaalsContact O-N 3.1Å; G437-L440 PolarHBondContact O-N 3.08Å; G437-T460 WeakPolarHBondContact CA-OG1 3.33Å; G437-Y461 PolarHBondContact N-O 2.78Å
438T95.6Very high93.6Very high1 Ų119.4 Ų19.41%0.0069%0.093CC..G310 helixtrans-53.4-39.1-166-52.90000114.5L374 F436 R447 L463 W464L374-T438 HydrophobicContact CD1-CG2 4.05Å; L374-T438 WeakPolarHBondContact CD2-O 3.46Å; F436-T438 VanDerWaalsContact C-N 3.27Å; F436-T438 PolarHBondContact O-N 2.97Å; T438-R447 PolarHBondContact O-NH1 3.34Å; T438-L463 WeakPolarHBondContact OG1-CB 2.79Å; T438-L463 PolarHBondContact OG1-N 3.5Å; T438-W464 HydrophobicContact CG2-CH2 4.37Å; T438-W464 HydrophobicContact CG2-CZ2 3.62Å
439F96.4Very high92.6Very high5 Ų523.1 Ų23.12%0.02211%0.111CC..G310 helixtrans-112.912.9-173.6-60.3-57.5000114.4I369 L374 F380 H386 F399 L427 L431 G437 C441 L463 W464I369-F439 HydrophobicContact CG2-CE1 3.82Å; I369-F439 HydrophobicContact CG2-CZ 4.24Å; L374-F439 HydrophobicContact CD1-CE1 4.24Å; L374-F439 HydrophobicContact CD2-CD1 3.88Å; L374-F439 HydrophobicContact CD2-CE1 4.23Å; F380-F439 WeakPolarHBondContact CB-O 3.49Å; F380-F439 HydrophobicContact CD1-CB 4.13Å; F380-F439 AromaticContact CD1-CD1 3.99Å; F380-F439 HydrophobicContact CD1-CD1 3.99Å; F380-F439 HydrophobicContact CD1-CG 4.36Å; F380-F439 HydrophobicContact CD2-CD1 4.41Å; F380-F439 AromaticContact CE1-CD1 3.62Å; F380-F439 HydrophobicContact CE1-CD1 3.62Å; F380-F439 HydrophobicContact CE1-CE1 4.13Å; F380-F439 HydrophobicContact CE1-CG 4.31Å; F380-F439 HydrophobicContact CE2-CD1 4.09Å; F380-F439 HydrophobicContact CG-CB 4.32Å; F380-F439 HydrophobicContact CG-CD1 4.36Å; F380-F439 AromaticContact CZ-CD1 3.67Å; F380-F439 HydrophobicContact CZ-CD1 3.67Å; F380-F439 AromaticContact CZ-CE1 3.96Å; F380-F439 HydrophobicContact CZ-CE1 3.96Å; H386-F439 PolarHBondContact CD2-O 3.25Å; H386-F439 PolarHBondContact NE2-O 3.47Å; F399-F439 HydrophobicContact CE1-CE1 4.49Å; F399-F439 HydrophobicContact CE1-CZ 4.29Å; F399-F439 HydrophobicContact CZ-CE1 4.42Å; F399-F439 HydrophobicContact CZ-CZ 4.42Å; L427-F439 HydrophobicContact CD2-CE2 4.13Å; L427-F439 HydrophobicContact CD2-CZ 4.07Å; L431-F439 HydrophobicContact CD1-CB 4.11Å; L431-F439 HydrophobicContact CD1-CD1 4.49Å; L431-F439 HydrophobicContact CD1-CD2 4.25Å; L431-F439 HydrophobicContact CD1-CG 4.05Å; G437-F439 VanDerWaalsContact C-N 3.3Å; G437-F439 PolarHBondContact O-N 3.48Å; G437-F439 VanDerWaalsContact O-N 3.1Å; F439-C441 PolarHBondContact O-N 2.9Å; F439-L463 HydrophobicContact CD2-CD2 4.19Å; F439-L463 HydrophobicContact CE2-CD2 3.5Å; F439-L463 HydrophobicContact CZ-CD2 4.39Å; F439-W464 AromaticContact CZ-CH2 3.81Å; F439-W464 HydrophobicContact CZ-CH2 3.81Å; F439-W464 HydrophobicContact CZ-CZ2 4.24Å
440L94.6Very high90.8Very high2 Ų225.4 Ų25.41%0.0113%0.129CC..SBendtrans-79.9-19.5-169.2-58.7-173.4000115.4I105 L108 A110 F111 S381 C434 F436 G437 L456I105-L440 HydrophobicContact CG2-CB 4.5Å; L108-L440 HydrophobicContact CD1-CD1 4.29Å; L108-L440 HydrophobicContact CD1-CD2 3.94Å; A110-L440 HydrophobicContact CB-CD1 3.62Å; F111-L440 HydrophobicContact CE2-CD1 3.99Å; S381-L440 WeakPolarHBondContact CB-O 3.35Å; C434-L440 HydrophobicContact CB-CD2 3.99Å; F436-L440 WeakPolarHBondContact O-CG 3.28Å; G437-L440 PolarHBondContact O-N 3.08Å; L440-L456 HydrophobicContact CD1-CD1 4.19Å
441C93.9Very high88.8Confident5 Ų534.4 Ų34.43%0.03417%0.168CC..  trans-109.4159.1-170.4-60.20000112.5F439 E446 R447F439-C441 PolarHBondContact O-N 2.9Å; C441-E446 HydrophobicContact CB-CB 3.82Å; C441-R447 HydrophobicContact CB-CG 3.69Å
442N94.8Very high86.9Confident20 Ų2034.9 Ų34.911%0.10717%0.171CC..SBendtrans-90.2-11.8178.6-71.5-39.7000114.1G377 K379 F380 S381 D382 E446G377-N442 CarbonylContact C-O 3.58Å; K379-N442 WeakPolarHBondContact CA-OD1 3.5Å; K379-N442 HydrophobicContact CB-CB 4.17Å; K379-N442 WeakPolarHBondContact CB-OD1 3.1Å; K379-N442 HydrophobicContact CG-CB 4.27Å; K379-N442 PolarHBondContact O-OD1 3.4Å; F380-N442 PolarHBondContact N-OD1 2.97Å; S381-N442 WeakPolarHBondContact CB-OD1 3.44Å; S381-N442 PolarHBondContact N-OD1 3.38Å; D382-N442 VanDerWaalsContact CG-ND2 3.31Å; D382-N442 PolarHBondContact N-OD1 3.42Å; D382-N442 VanDerWaalsContact N-OD1 3.08Å; D382-N442 PolarHBondContact OD1-ND2 2.82Å; N442-E446 WeakPolarHBondContact CB-OE1 3.32Å; N442-E446 WeakPolarHBondContact CB-OE2 3.33Å; N442-E446 PolarHBondContact N-OE2 3.11Å
443S93.3Very high85Confident10 Ų1038.7 Ų38.77%0.0720%0.198CC..SBendtrans-152.4161-174.964.70000112.7K445 E446 R447S443-K445 PolarHBondContact O-N 3.05Å; S443-E446 PolarHBondContact O-N 3.14Å; S443-E446 VanDerWaalsContact OG-CD 3.28Å; S443-E446 WeakPolarHBondContact OG-CG 3.09Å; S443-E446 PolarHBondContact OG-N 2.91Å; S443-E446 PolarHBondContact OG-OE1 2.88Å; S443-R447 WeakPolarHBondContact O-CG 3.43Å; S443-R447 PolarHBondContact O-N 3.11Å
444H92.1Very high83.7Confident19 Ų1939.3 Ų39.39%0.08820%0.199CC..Hα-helixtrans-63.9-33.1170.9-168.960.3000112F154 M375 R447 L448F154-H444 HydrophobicContact CE1-CB 4.19Å; F154-H444 AromaticContact CE1-CD2 3.91Å; F154-H444 AromaticContact CZ-CD2 3.82Å; M375-H444 WeakPolarHBondContact O-CB 3Å; H444-R447 PolarHBondContact O-N 3.29Å; H444-L448 VanDerWaalsContact NE2-CD1 3.27Å; H444-L448 WeakPolarHBondContact NE2-CD1 3.33Å; H444-L448 PolarHBondContact O-N 2.89Å
445K92.3Very high83Confident43 Ų4343.3 Ų43.319%0.18722%0.217CC..Hα-helixtrans-55.9-55.9173.5179.6177.4172.61730111.8F154 E158 S443 R447 L448 E449F154-K445 HydrophobicContact CB-CB 4.39Å; F154-K445 HydrophobicContact CB-CD 3.84Å; F154-K445 HydrophobicContact CB-CG 4.26Å; F154-K445 HydrophobicContact CD1-CB 3.7Å; F154-K445 HydrophobicContact CD1-CG 4.37Å; F154-K445 HydrophobicContact CD2-CB 3.71Å; F154-K445 HydrophobicContact CD2-CD 4.08Å; F154-K445 HydrophobicContact CD2-CG 3.57Å; F154-K445 HydrophobicContact CE1-CB 3.79Å; F154-K445 HydrophobicContact CE2-CB 3.83Å; F154-K445 HydrophobicContact CE2-CG 3.97Å; F154-K445 HydrophobicContact CG-CB 3.65Å; F154-K445 HydrophobicContact CG-CD 3.95Å; F154-K445 HydrophobicContact CG-CG 3.8Å; F154-K445 HydrophobicContact CZ-CB 3.86Å; E158-K445 HydrophobicContact CB-CD 4.06Å; E158-K445 HydrophobicContact CG-CD 3.95Å; E158-K445 IonicContact OE1-NZ 3.58Å; E158-K445 PolarHBondContact OE1-NZ 2.78Å; S443-K445 PolarHBondContact O-N 3.05Å; K445-R447 PolarHBondContact O-N 3.28Å; K445-L448 PolarHBondContact O-N 3.29Å; K445-L448 VanDerWaalsContact O-N 3.08Å; K445-E449 WeakPolarHBondContact CE-OE1 3.38Å; K445-E449 HydrophobicContact CG-CG 4.23Å; K445-E449 IonicContact NZ-OE1 3.61Å; K445-E449 WeakPolarHBondContact O-CG 3.09Å; K445-E449 PolarHBondContact O-N 2.98Å
446E91Very high82.8Confident52 Ų5241.4 Ų41.424%0.24321%0.207CC..Hα-helixtrans-57.5-34.9178.3-74.9158.8-126.500112.4C441 N442 S443 Y454C441-E446 HydrophobicContact CB-CB 3.82Å; N442-E446 WeakPolarHBondContact CB-OE1 3.32Å; N442-E446 WeakPolarHBondContact CB-OE2 3.33Å; N442-E446 PolarHBondContact N-OE2 3.11Å; S443-E446 PolarHBondContact O-N 3.14Å; S443-E446 VanDerWaalsContact OG-CD 3.28Å; S443-E446 WeakPolarHBondContact OG-CG 3.09Å; S443-E446 PolarHBondContact OG-N 2.91Å; S443-E446 PolarHBondContact OG-OE1 2.88Å; E446-Y454 PolarHBondContact O-OH 3.49Å; E446-Y454 VanDerWaalsContact O-OH 3.13Å
447R89.1Confident82.4Confident29 Ų2943.7 Ų43.711%0.10922%0.223CC..Hα-helixtrans-69.8-35.9177.3-69174.254.3146.4-17113.4E370 L374 T438 C441 S443 H444 K445 L456E370-R447 IonicContact OE1-NH2 3.72Å; E370-R447 IonicContact OE2-CZ 2.88Å; E370-R447 IonicContact OE2-NH1 3.47Å; E370-R447 IonicContact OE2-NH2 3.23Å; E370-R447 PolarHBondContact OE2-NH2 2.93Å; L374-R447 VanDerWaalsContact CB-NH1 3.29Å; T438-R447 PolarHBondContact O-NH1 3.34Å; C441-R447 HydrophobicContact CB-CG 3.69Å; S443-R447 WeakPolarHBondContact O-CG 3.43Å; S443-R447 PolarHBondContact O-N 3.11Å; H444-R447 PolarHBondContact O-N 3.29Å; K445-R447 PolarHBondContact O-N 3.28Å; R447-L456 HydrophobicContact CB-CD2 4.25Å; R447-L456 HydrophobicContact CG-CD2 3.9Å
448L86.1Confident82.1Confident78 Ų7849.2 Ų49.241%0.40825%0.249SC..Hα-helixtrans-93.3-19.6-174.9-72.2-167.8000114.3F154 H444 K445 T450F154-L448 HydrophobicContact CZ-CD1 4.21Å; H444-L448 VanDerWaalsContact NE2-CD1 3.27Å; H444-L448 WeakPolarHBondContact NE2-CD1 3.33Å; H444-L448 PolarHBondContact O-N 2.89Å; K445-L448 PolarHBondContact O-N 3.29Å; K445-L448 VanDerWaalsContact O-N 3.08Å; L448-T450 PolarHBondContact O-N 2.66Å
449E75.7Confident81.9Confident79 Ų7953.8 Ų53.837%0.36927%0.269SS..  trans-56.4102.3-175.9-90179.9173.200111.3K445 K451 S452K445-E449 WeakPolarHBondContact CE-OE1 3.38Å; K445-E449 HydrophobicContact CG-CG 4.23Å; K445-E449 IonicContact NZ-OE1 3.61Å; K445-E449 WeakPolarHBondContact O-CG 3.09Å; K445-E449 PolarHBondContact O-N 2.98Å; E449-K451 PolarHBondContact O-N 3.35Å; E449-S452 WeakPolarHBondContact O-CB 3.17Å; E449-S452 PolarHBondContact O-N 2.79Å
450T55.5Low81.8Confident106 Ų10653.5 Ų53.565%0.6527%0.268SS*.THydrogen-bonded Turntrans-71.3-24.5174.854.40000112.1L448L448-T450 PolarHBondContact O-N 2.66Å
451K53.4Low81.8Confident201 Ų20155.3 Ų55.387%0.87428%0.275SS*.THydrogen-bonded Turntrans-75.3-14.7169.4-66-174.2-177.9178.50112.5E449E449-K451 PolarHBondContact O-N 3.35Å
452S56Low81.9Confident10 Ų1055 Ų557%0.0727%0.273CS..SBendtrans-63132169.6-177.70000108.3E449 Y454 K455E449-S452 WeakPolarHBondContact O-CB 3.17Å; E449-S452 PolarHBondContact O-N 2.79Å; S452-Y454 PolarHBondContact O-N 2.88Å; S452-Y454 WeakPolarHBondContact OG-CD1 3.31Å; S452-Y454 WeakPolarHBondContact OG-CE1 3.06Å; S452-K455 PolarHBondContact O-N 3.23Å
453P54.9Low82Confident96 Ų9654.1 Ų54.162%0.62327%0.268SS*.THydrogen-bonded Turntrans-56.2-19.3-177.621.7-33.6000113.7E106 K459E106-P453 WeakPolarHBondContact OE1-CG 3.3Å; P453-K459 PolarHBondContact O-NZ 3.48Å
454Y66.1Low82.1Confident20 Ų2053.8 Ų53.88%0.07827%0.265CS..THydrogen-bonded Turntrans-98.3-19.3-170.756.5-106000116.7E106 F111 E446 S452 L456 K459E106-Y454 HydrophobicContact CG-CD1 4.23Å; E106-Y454 HydrophobicContact CG-CG 4.42Å; E106-Y454 WeakPolarHBondContact OE1-CD1 3.45Å; F111-Y454 HydrophobicContact CE1-CD2 4.49Å; F111-Y454 HydrophobicContact CE1-CG 4.41Å; F111-Y454 HydrophobicContact CZ-CD2 4.23Å; F111-Y454 HydrophobicContact CZ-CG 4.26Å; E446-Y454 PolarHBondContact O-OH 3.49Å; E446-Y454 VanDerWaalsContact O-OH 3.13Å; S452-Y454 PolarHBondContact O-N 2.88Å; S452-Y454 WeakPolarHBondContact OG-CD1 3.31Å; S452-Y454 WeakPolarHBondContact OG-CE1 3.06Å; Y454-L456 HydrophobicContact CD2-CB 4.12Å; Y454-L456 HydrophobicContact CE2-CB 4.21Å; Y454-L456 PolarHBondContact O-N 2.98Å; Y454-K459 WeakPolarHBondContact O-CD 3.38Å; Y454-K459 WeakPolarHBondContact O-CE 3.39Å; Y454-K459 VanDerWaalsContact O-CG 3.27Å; Y454-K459 WeakPolarHBondContact O-CG 3.38Å
455K79.8Confident82.3Confident86 Ų8653 Ų5337%0.37426%0.262SS..  trans40.966.2178.3-57.7-167.3176.9-171.40113.6S452 C457 E458 K459S452-K455 PolarHBondContact O-N 3.23Å; K455-C457 PolarHBondContact O-N 3.41Å; K455-C457 VanDerWaalsContact O-N 3.16Å; K455-E458 HydrophobicContact CB-CB 4.02Å; K455-E458 HydrophobicContact CB-CG 4.4Å; K455-E458 VanDerWaalsContact CD-CD 3.46Å; K455-E458 WeakPolarHBondContact CD-OE2 3.34Å; K455-E458 IonicContact NZ-OE1 2.83Å; K455-E458 IonicContact NZ-OE2 3.65Å; K455-E458 PolarHBondContact NZ-OE2 2.72Å; K455-E458 WeakPolarHBondContact O-CA 3.49Å; K455-E458 WeakPolarHBondContact O-CB 2.93Å; K455-E458 PolarHBondContact O-N 2.83Å; K455-K459 PolarHBondContact O-N 2.92Å
456L88.9Confident82.3Confident2 Ų253.1 Ų53.11%0.0126%0.262CS..Hα-helixtrans-44.2-54.9-163.2-175.170.1000114.6F111 W126 L440 R447 Y454 E458 K459 T460F111-L456 HydrophobicContact CZ-CD1 3.91Å; W126-L456 HydrophobicContact CH2-CD2 4.28Å; W126-L456 HydrophobicContact CH2-CG 4.28Å; L440-L456 HydrophobicContact CD1-CD1 4.19Å; R447-L456 HydrophobicContact CB-CD2 4.25Å; R447-L456 HydrophobicContact CG-CD2 3.9Å; Y454-L456 HydrophobicContact CD2-CB 4.12Å; Y454-L456 HydrophobicContact CE2-CB 4.21Å; Y454-L456 PolarHBondContact O-N 2.98Å; L456-E458 VanDerWaalsContact C-N 3.29Å; L456-E458 PolarHBondContact O-N 3.35Å; L456-K459 PolarHBondContact O-N 2.99Å; L456-T460 HydrophobicContact CD1-CG2 4.16Å; L456-T460 WeakPolarHBondContact O-CB 3.49Å; L456-T460 PolarHBondContact O-N 3.29Å; L456-T460 PolarHBondContact O-OG1 2.87Å
457C87.5Confident82.5Confident53 Ų5350.9 Ų50.936%0.35825%0.252SS..Hα-helixtrans-68-26.8-177.4-52.30000113.1W126 K455W126-C457 HydrophobicContact CD2-CB 3.98Å; W126-C457 HydrophobicContact CE3-CB 4.37Å; W126-C457 HydrophobicContact CG-CB 4.19Å; K455-C457 PolarHBondContact O-N 3.41Å; K455-C457 VanDerWaalsContact O-N 3.16Å
458E88.3Confident82.7Confident116 Ų11652.2 Ų52.254%0.54227%0.269SS..Hα-helixtrans-83.6-11.9178.4-66.4179-146.600113.4Q122 K455 L456Q122-E458 PolarHBondContact NE2-O 2.78Å; K455-E458 HydrophobicContact CB-CB 4.02Å; K455-E458 HydrophobicContact CB-CG 4.4Å; K455-E458 VanDerWaalsContact CD-CD 3.46Å; K455-E458 WeakPolarHBondContact CD-OE2 3.34Å; K455-E458 IonicContact NZ-OE1 2.83Å; K455-E458 IonicContact NZ-OE2 3.65Å; K455-E458 PolarHBondContact NZ-OE2 2.72Å; K455-E458 WeakPolarHBondContact O-CA 3.49Å; K455-E458 WeakPolarHBondContact O-CB 2.93Å; K455-E458 PolarHBondContact O-N 2.83Å; L456-E458 VanDerWaalsContact C-N 3.29Å; L456-E458 PolarHBondContact O-N 3.35Å
459K91.1Very high82.8Confident97 Ų9754.1 Ų54.142%0.42227%0.27SS..Hα-helixtrans-123.8-4.3-177-61.4-163.2-167.7169.30114.9F111 P453 Y454 K455 L456F111-K459 HydrophobicContact CD1-CB 3.95Å; F111-K459 HydrophobicContact CE1-CB 4.15Å; P453-K459 PolarHBondContact O-NZ 3.48Å; Y454-K459 WeakPolarHBondContact O-CD 3.38Å; Y454-K459 WeakPolarHBondContact O-CE 3.39Å; Y454-K459 VanDerWaalsContact O-CG 3.27Å; Y454-K459 WeakPolarHBondContact O-CG 3.38Å; K455-K459 PolarHBondContact O-N 2.92Å; L456-K459 PolarHBondContact O-N 2.99Å
460T94.2Very high83.4Confident0 Ų053.2 Ų53.20%027%0.265CS..SBendtrans-136.7156.6-175.469.40000111.5A110 F111 W126 G437 L456A110-T460 HydrophobicContact CB-CG2 3.88Å; F111-T460 HydrophobicContact CD1-CG2 3.65Å; F111-T460 HydrophobicContact CD2-CG2 4.24Å; F111-T460 HydrophobicContact CE1-CG2 3.51Å; F111-T460 HydrophobicContact CE2-CG2 4.11Å; F111-T460 HydrophobicContact CG-CG2 4.02Å; F111-T460 HydrophobicContact CZ-CG2 3.78Å; W126-T460 WeakPolarHBondContact CZ2-OG1 3.27Å; W126-T460 PolarHBondContact NE1-O 2.88Å; G437-T460 WeakPolarHBondContact CA-OG1 3.33Å; L456-T460 HydrophobicContact CD1-CG2 4.16Å; L456-T460 WeakPolarHBondContact O-CB 3.49Å; L456-T460 PolarHBondContact O-N 3.29Å; L456-T460 PolarHBondContact O-OG1 2.87Å
461Y95Very high85Confident39 Ų3953.1 Ų53.115%0.15326%0.256CS..  trans-84.6145.8174.4-66.2-98.4000110.7Y113 P115 L120 Q122 F436 G437Y113-Y461 AromaticContact CD1-CD2 3.74Å; Y113-Y461 HydrophobicContact CD1-CD2 3.74Å; Y113-Y461 HydrophobicContact CD1-CE2 4.31Å; Y113-Y461 HydrophobicContact CD1-CG 4.24Å; Y113-Y461 HydrophobicContact CE1-CD2 4.37Å; Y113-Y461 WeakPolarHBondContact O-CE2 3.45Å; P115-Y461 VanDerWaalsContact CD-CZ 3.45Å; P115-Y461 WeakPolarHBondContact CD-OH 3.18Å; P115-Y461 HydrophobicContact CG-CD1 3.99Å; P115-Y461 HydrophobicContact CG-CD2 4.3Å; P115-Y461 HydrophobicContact CG-CE1 3.48Å; P115-Y461 VanDerWaalsContact CG-CE1 3.48Å; P115-Y461 HydrophobicContact CG-CE2 3.87Å; P115-Y461 HydrophobicContact CG-CG 4.37Å; P115-Y461 VanDerWaalsContact CG-CZ 3.43Å; L120-Y461 HydrophobicContact CD2-CD1 3.9Å; L120-Y461 HydrophobicContact CD2-CE1 4.47Å; L120-Y461 HydrophobicContact CG-CD1 3.8Å; L120-Y461 HydrophobicContact CG-CE1 4.16Å; Q122-Y461 VanDerWaalsContact CA-CE1 3.49Å; Q122-Y461 HydrophobicContact CB-CD1 4.28Å; Q122-Y461 HydrophobicContact CB-CE1 3.93Å; Q122-Y461 HydrophobicContact CG-CD1 4.24Å; Q122-Y461 HydrophobicContact CG-CD2 4.23Å; Q122-Y461 HydrophobicContact CG-CE1 4.17Å; Q122-Y461 HydrophobicContact CG-CE2 4.14Å; Q122-Y461 HydrophobicContact CG-CG 4.27Å; F436-Y461 CarbonylContact C-O 3.55Å; F436-Y461 WeakPolarHBondContact CA-O 3.36Å; F436-Y461 WeakPolarHBondContact CB-O 3.41Å; G437-Y461 PolarHBondContact N-O 2.78Å
462S95.3Very high86.4Confident0 Ų046 Ų460%023%0.226CC..  trans-79.1139.3169.4179.10000111D124 G125 W464 G465 Y466D124-S462 WeakPolarHBondContact O-CB 3.45Å; G125-S462 PolarHBondContact O-OG 2.93Å; G125-S462 VanDerWaalsContact O-OG 3.06Å; S462-W464 PolarHBondContact O-N 2.98Å; S462-W464 PolarHBondContact OG-N 3.39Å; S462-G465 PolarHBondContact O-N 3.5Å; S462-Y466 PolarHBondContact O-N 3.44Å
463L96.4Very high87.8Confident1 Ų146.3 Ų46.31%0.00523%0.226CC..Hα-helixtrans-60.8-30.9170.8177.260.1000111.2L427 H430 F436 T438 F439 Y466 M467L427-L463 HydrophobicContact CD2-CD2 3.85Å; H430-L463 HydrophobicContact CB-CD1 3.6Å; H430-L463 HydrophobicContact CB-CD2 3.83Å; H430-L463 HydrophobicContact CB-CG 4.36Å; F436-L463 HydrophobicContact CB-CB 3.92Å; F436-L463 HydrophobicContact CD2-CB 4.13Å; F436-L463 HydrophobicContact CD2-CD1 3.57Å; F436-L463 HydrophobicContact CD2-CG 4.41Å; F436-L463 HydrophobicContact CE2-CD1 3.68Å; F436-L463 HydrophobicContact CG-CB 3.99Å; F436-L463 HydrophobicContact CG-CD1 4.23Å; F436-L463 HydrophobicContact CZ-CD1 4.44Å; T438-L463 WeakPolarHBondContact OG1-CB 2.79Å; T438-L463 PolarHBondContact OG1-N 3.5Å; F439-L463 HydrophobicContact CD2-CD2 4.19Å; F439-L463 HydrophobicContact CE2-CD2 3.5Å; F439-L463 HydrophobicContact CZ-CD2 4.39Å; L463-Y466 HydrophobicContact CD1-CD1 3.97Å; L463-Y466 WeakPolarHBondContact O-CB 3.33Å; L463-Y466 PolarHBondContact O-N 2.82Å; L463-M467 HydrophobicContact CD1-CG 3.79Å; L463-M467 HydrophobicContact CD1-SD 3.98Å; L463-M467 HydrophobicContact CD2-SD 4.02Å; L463-M467 HydrophobicContact CG-CG 4.02Å; L463-M467 HydrophobicContact CG-SD 3.73Å; L463-M467 WeakPolarHBondContact O-CG 3.33Å; L463-M467 PolarHBondContact O-N 2.89Å
464W96.4Very high89.7Confident2 Ų241.8 Ų41.81%0.00820%0.197CC..Hα-helixtrans-64.2-43.6179.8-49.6140.7000112N129 Q366 I369 E370 L427 T438 F439 S462 Y466 M467 A468N129-W464 VanDerWaalsContact ND2-CD1 3.33Å; N129-W464 VanDerWaalsContact ND2-CG 3.33Å; Q366-W464 HydrophobicContact CB-CD2 4.43Å; Q366-W464 HydrophobicContact CG-CD2 4.08Å; Q366-W464 HydrophobicContact CG-CE3 3.72Å; Q366-W464 HydrophobicContact CG-CH2 4.27Å; Q366-W464 HydrophobicContact CG-CZ3 3.83Å; I369-W464 HydrophobicContact CD1-CH2 4.3Å; I369-W464 HydrophobicContact CG2-CH2 4.32Å; I369-W464 HydrophobicContact CG2-CZ2 4.25Å; E370-W464 HydrophobicContact CG-CZ2 4.48Å; E370-W464 PolarHBondContact OE1-NE1 2.84Å; L427-W464 HydrophobicContact CD2-CH2 3.8Å; L427-W464 HydrophobicContact CD2-CZ3 3.57Å; T438-W464 HydrophobicContact CG2-CH2 4.37Å; T438-W464 HydrophobicContact CG2-CZ2 3.62Å; F439-W464 AromaticContact CZ-CH2 3.81Å; F439-W464 HydrophobicContact CZ-CH2 3.81Å; F439-W464 HydrophobicContact CZ-CZ2 4.24Å; S462-W464 PolarHBondContact O-N 2.98Å; S462-W464 PolarHBondContact OG-N 3.39Å; W464-Y466 VanDerWaalsContact C-N 3.31Å; W464-Y466 PolarHBondContact O-N 3.44Å; W464-M467 HydrophobicContact CE3-SD 4.28Å; W464-M467 HydrophobicContact CZ3-SD 4.15Å; W464-M467 PolarHBondContact O-N 3.39Å; W464-A468 WeakPolarHBondContact O-CB 3.34Å; W464-A468 PolarHBondContact O-N 2.92Å
465G94.6Very high91Very high2 Ų244.5 Ų44.52%0.02121%0.207CC..Hα-helixtrans-60-43.1175.100000111.5D124 S462D124-G465 WeakPolarHBondContact O-CA 2.97Å; S462-G465 PolarHBondContact O-N 3.5Å
466Y94.1Very high91.8Very high47 Ų4740.9 Ų40.918%0.18419%0.192CC..Hα-helixtrans-62.6-50.5175.4173.6-99.2000112.8L120 H430 F436 S462 L463 W464 A468 R469 K470L120-Y466 HydrophobicContact CD2-CD2 4.4Å; H430-Y466 AromaticContact CD2-CE1 3.96Å; H430-Y466 AromaticContact NE2-CE1 3.38Å; H430-Y466 WeakPolarHBondContact NE2-CE1 3.44Å; H430-Y466 AromaticContact NE2-CZ 3.94Å; F436-Y466 HydrophobicContact CE1-CD2 4.15Å; F436-Y466 AromaticContact CE1-CG 3.86Å; F436-Y466 HydrophobicContact CE1-CG 3.86Å; F436-Y466 HydrophobicContact CE2-CD1 4.02Å; F436-Y466 HydrophobicContact CE2-CE1 4.45Å; F436-Y466 HydrophobicContact CE2-CG 4.1Å; F436-Y466 AromaticContact CZ-CD1 3.71Å; F436-Y466 HydrophobicContact CZ-CD1 3.71Å; F436-Y466 AromaticContact CZ-CD2 3.61Å; F436-Y466 HydrophobicContact CZ-CD2 3.61Å; F436-Y466 HydrophobicContact CZ-CE1 4.27Å; F436-Y466 HydrophobicContact CZ-CE2 4.18Å; F436-Y466 AromaticContact CZ-CG 3.33Å; F436-Y466 HydrophobicContact CZ-CG 3.33Å; S462-Y466 PolarHBondContact O-N 3.44Å; L463-Y466 HydrophobicContact CD1-CD1 3.97Å; L463-Y466 WeakPolarHBondContact O-CB 3.33Å; L463-Y466 PolarHBondContact O-N 2.82Å; W464-Y466 VanDerWaalsContact C-N 3.31Å; W464-Y466 PolarHBondContact O-N 3.44Å; Y466-A468 VanDerWaalsContact C-N 3.3Å; Y466-A468 PolarHBondContact O-N 3.29Å; Y466-R469 PolarHBondContact O-N 3.21Å; Y466-K470 HydrophobicContact CD1-CD 4.36Å; Y466-K470 HydrophobicContact CE1-CD 3.68Å; Y466-K470 HydrophobicContact CE2-CD 4.44Å; Y466-K470 VanDerWaalsContact CZ-CE 3.5Å; Y466-K470 WeakPolarHBondContact OH-CE 3.44Å; Y466-K470 PolarHBondContact OH-NZ 3.01Å
467M94.6Very high92Very high5 Ų542 Ų423%0.02520%0.199CC..Hα-helixtrans-66.3-30.8-178.3-68.9-177.779.900112.5Y423 T426 L427 L463 W464 R469 K470 K471 L474Y423-M467 HydrophobicContact CD1-CE 4.21Å; Y423-M467 HydrophobicContact CD2-CE 3.35Å; Y423-M467 HydrophobicContact CE1-CE 4.12Å; Y423-M467 HydrophobicContact CE2-CE 3.25Å; Y423-M467 HydrophobicContact CE2-SD 4.31Å; Y423-M467 HydrophobicContact CG-CE 3.81Å; T426-M467 HydrophobicContact CG2-CE 3.91Å; T426-M467 HydrophobicContact CG2-CG 4.22Å; T426-M467 HydrophobicContact CG2-SD 4.32Å; L427-M467 HydrophobicContact CD2-CE 4.5Å; L427-M467 HydrophobicContact CD2-SD 4.04Å; L427-M467 HydrophobicContact CG-CE 4.21Å; L427-M467 HydrophobicContact CG-SD 4.38Å; L463-M467 HydrophobicContact CD1-CG 3.79Å; L463-M467 HydrophobicContact CD1-SD 3.98Å; L463-M467 HydrophobicContact CD2-SD 4.02Å; L463-M467 HydrophobicContact CG-CG 4.02Å; L463-M467 HydrophobicContact CG-SD 3.73Å; L463-M467 WeakPolarHBondContact O-CG 3.33Å; L463-M467 PolarHBondContact O-N 2.89Å; W464-M467 HydrophobicContact CE3-SD 4.28Å; W464-M467 HydrophobicContact CZ3-SD 4.15Å; W464-M467 PolarHBondContact O-N 3.39Å; M467-R469 PolarHBondContact O-N 3.45Å; M467-K470 CarbonylContact O-C 3.56Å; M467-K470 WeakPolarHBondContact O-CA 3.09Å; M467-K470 WeakPolarHBondContact O-CB 3.27Å; M467-K470 PolarHBondContact O-N 3.36Å; M467-K471 PolarHBondContact O-N 3.28Å; M467-L474 HydrophobicContact CB-CD1 4.03Å; M467-L474 HydrophobicContact CE-CD1 3.63Å; M467-L474 HydrophobicContact CG-CD1 4.24Å
468A93Very high92.2Very high57 Ų5743.6 Ų43.647%0.47120%0.204SC..Hα-helixtrans-60.3-32.417500000112.6W464 Y466 K470 K471W464-A468 WeakPolarHBondContact O-CB 3.34Å; W464-A468 PolarHBondContact O-N 2.92Å; Y466-A468 VanDerWaalsContact C-N 3.3Å; Y466-A468 PolarHBondContact O-N 3.29Å; A468-K470 PolarHBondContact O-N 3.37Å; A468-K471 WeakPolarHBondContact O-CB 3.21Å; A468-K471 PolarHBondContact O-N 3.12Å
469R88.4Confident92.6Very high117 Ų11739.4 Ų39.444%0.44218%0.183SC..Hα-helixtrans-71.1-21.2176.2-55.8-55.1177.5-174.6-3.8113D119 D124 Y466 M467 K648D119-R469 PolarHBondContact O-NE 3.09Å; D119-R469 PolarHBondContact O-NH2 3.2Å; D119-R469 VanDerWaalsContact O-NH2 3.13Å; D124-R469 IonicContact OD1-NH2 3.09Å; D124-R469 IonicContact OD2-CZ 2.79Å; D124-R469 IonicContact OD2-NE 2.83Å; D124-R469 IonicContact OD2-NH2 2.61Å; D124-R469 PolarHBondContact OD2-NH2 3.23Å; Y466-R469 PolarHBondContact O-N 3.21Å; M467-R469 PolarHBondContact O-N 3.45Å; R469-K648 PolarHBondContact O-NZ 3.31Å
470K88.3Confident92.5Very high60 Ų6038.4 Ų38.426%0.26118%0.183SC..THydrogen-bonded Turntrans-99.314.9179.6-72.1174.1151.5-125.50113.6Y466 M467 A468 E472 E473 L474Y466-K470 HydrophobicContact CD1-CD 4.36Å; Y466-K470 HydrophobicContact CE1-CD 3.68Å; Y466-K470 HydrophobicContact CE2-CD 4.44Å; Y466-K470 VanDerWaalsContact CZ-CE 3.5Å; Y466-K470 WeakPolarHBondContact OH-CE 3.44Å; Y466-K470 PolarHBondContact OH-NZ 3.01Å; M467-K470 CarbonylContact O-C 3.56Å; M467-K470 WeakPolarHBondContact O-CA 3.09Å; M467-K470 WeakPolarHBondContact O-CB 3.27Å; M467-K470 PolarHBondContact O-N 3.36Å; A468-K470 PolarHBondContact O-N 3.37Å; K470-E472 VanDerWaalsContact C-N 3.27Å; K470-E472 PolarHBondContact O-N 3.22Å; K470-E472 VanDerWaalsContact O-N 3.07Å; K470-E473 HydrophobicContact CB-CG 3.76Å; K470-E473 WeakPolarHBondContact CB-OE1 3.47Å; K470-E473 WeakPolarHBondContact CD-OE1 3.17Å; K470-E473 VanDerWaalsContact CE-OE1 3.28Å; K470-E473 WeakPolarHBondContact CE-OE1 3.37Å; K470-E473 HydrophobicContact CG-CG 4.31Å; K470-E473 WeakPolarHBondContact CG-OE1 3.03Å; K470-E473 IonicContact NZ-OE1 3.2Å; K470-E473 PolarHBondContact NZ-OE1 2.79Å; K470-E473 WeakPolarHBondContact O-CG 3.46Å; K470-E473 PolarHBondContact O-N 3.45Å; K470-L474 HydrophobicContact CB-CD1 3.92Å; K470-L474 HydrophobicContact CB-CG 4.06Å; K470-L474 WeakPolarHBondContact O-CG 3.2Å; K470-L474 PolarHBondContact O-N 3.08Å
471K87.9Confident92.4Very high105 Ų10542 Ų4246%0.45721%0.208SC..Hα-helixtrans-47.3-44-175.9-172.5177.4-178.7178.80114.4M467 A468 E473 L474 R475M467-K471 PolarHBondContact O-N 3.28Å; A468-K471 WeakPolarHBondContact O-CB 3.21Å; A468-K471 PolarHBondContact O-N 3.12Å; K471-E473 PolarHBondContact O-N 3.14Å; K471-L474 PolarHBondContact O-N 3.27Å; K471-R475 VanDerWaalsContact O-CB 3.3Å; K471-R475 WeakPolarHBondContact O-CB 3.08Å; K471-R475 PolarHBondContact O-N 3.41Å
472E83.1Confident92.3Very high51 Ų5147.3 Ų47.324%0.23824%0.239CC..Hα-helixtrans-68.6-30.3-176.8-57.2-60128.800113.7K470 R660K470-E472 VanDerWaalsContact C-N 3.27Å; K470-E472 PolarHBondContact O-N 3.22Å; K470-E472 VanDerWaalsContact O-N 3.07Å; E472-R660 VanDerWaalsContact CD-NH1 3.31Å; E472-R660 IonicContact OE1-CZ 2.65Å; E472-R660 IonicContact OE1-NH1 3.55Å; E472-R660 PolarHBondContact OE1-NH1 2.89Å; E472-R660 IonicContact OE2-CZ 3.56Å; E472-R660 IonicContact OE2-NH1 3.51Å; E472-R660 PolarHBondContact OE2-NH1 3.26Å; E472-R660 VanDerWaalsContact OE2-NH1 3.12Å; E472-R660 IonicContact OE2-NH2 2.69Å; E472-R660 PolarHBondContact OE2-NH2 3.43Å; E472-R660 VanDerWaalsContact OE2-NH2 3.13Å
473E86.8Confident92.1Very high16 Ų1653 Ų538%0.07527%0.27CS..Hα-helixtrans-85.2-21178.264.2173.5-147.500112.9N420 R422 K470 K471 Y629 H631N420-E473 PolarHBondContact ND2-O 3.49Å; R422-E473 PolarHBondContact NH1-O 3.1Å; K470-E473 HydrophobicContact CB-CG 3.76Å; K470-E473 WeakPolarHBondContact CB-OE1 3.47Å; K470-E473 WeakPolarHBondContact CD-OE1 3.17Å; K470-E473 VanDerWaalsContact CE-OE1 3.28Å; K470-E473 WeakPolarHBondContact CE-OE1 3.37Å; K470-E473 HydrophobicContact CG-CG 4.31Å; K470-E473 WeakPolarHBondContact CG-OE1 3.03Å; K470-E473 IonicContact NZ-OE1 3.2Å; K470-E473 PolarHBondContact NZ-OE1 2.79Å; K470-E473 WeakPolarHBondContact O-CG 3.46Å; K470-E473 PolarHBondContact O-N 3.45Å; K471-E473 PolarHBondContact O-N 3.14Å; E473-Y629 HydrophobicContact CB-CD1 3.8Å; E473-Y629 HydrophobicContact CB-CE1 3.54Å; E473-Y629 HydrophobicContact CB-CG 4.42Å; E473-H631 IonicContact OE2-CE1 2.95Å; E473-H631 IonicContact OE2-NE2 3.14Å
474L93.9Very high92.1Very high2 Ų254.7 Ų54.71%0.0128%0.28CS..Hα-helixtrans-101.7-13.2-175.6-56.1-174.6000113.6F419 N420 R422 Y423 M467 K470 K471F419-L474 WeakPolarHBondContact CA-O 3.37Å; N420-L474 PolarHBondContact N-O 3.03Å; N420-L474 VanDerWaalsContact ND2-C 3.28Å; N420-L474 PolarHBondContact ND2-O 2.93Å; N420-L474 PolarHBondContact OD1-O 3.03Å; R422-L474 HydrophobicContact CB-CD2 4.23Å; R422-L474 HydrophobicContact CG-CD2 3.68Å; Y423-L474 HydrophobicContact CD2-CB 3.94Å; Y423-L474 HydrophobicContact CD2-CD1 3.96Å; M467-L474 HydrophobicContact CB-CD1 4.03Å; M467-L474 HydrophobicContact CE-CD1 3.63Å; M467-L474 HydrophobicContact CG-CD1 4.24Å; K470-L474 HydrophobicContact CB-CD1 3.92Å; K470-L474 HydrophobicContact CB-CG 4.06Å; K470-L474 WeakPolarHBondContact O-CG 3.2Å; K470-L474 PolarHBondContact O-N 3.08Å; K471-L474 PolarHBondContact O-N 3.27Å
475R94.5Very high92.1Very high76 Ų7657.2 Ų57.229%0.28730%0.298SS..BIsolated β-bridgetrans-74.9138.2175.1-169.1-176-17483.42.6110.4E418 N420 K471 P477E418-R475 HydrophobicContact CG-CG 4.41Å; E418-R475 CarbonylContact O-C 3.07Å; E418-R475 WeakPolarHBondContact O-CA 3.26Å; E418-R475 WeakPolarHBondContact O-CG 3.38Å; E418-R475 IonicContact OE1-CZ 2.86Å; E418-R475 IonicContact OE1-NH1 2.83Å; E418-R475 PolarHBondContact OE1-NH1 3.47Å; E418-R475 IonicContact OE1-NH2 2.62Å; N420-R475 PolarHBondContact ND2-O 2.84Å; K471-R475 VanDerWaalsContact O-CB 3.3Å; K471-R475 WeakPolarHBondContact O-CB 3.08Å; K471-R475 PolarHBondContact O-N 3.41Å; R475-P477 WeakPolarHBondContact O-CD 3.39Å
476N95Very high92.1Very high11 Ų1162.2 Ų62.26%0.05932%0.32CS..  trans-73.6117.2168.7-179.74.9000110.1P414 F417 E418 N420 L478 F479P414-N476 PolarHBondContact O-ND2 2.84Å; F417-N476 WeakPolarHBondContact O-CB 3.04Å; F417-N476 PolarHBondContact O-ND2 3.44Å; E418-N476 PolarHBondContact O-N 2.93Å; N420-N476 HydrophobicContact CB-CB 4.17Å; N476-L478 PolarHBondContact O-N 3.25Å; N476-L478 WeakPolarHBondContact OD1-CB 3.35Å; N476-L478 PolarHBondContact OD1-N 3.15Å; N476-F479 HydrophobicContact CB-CB 4.17Å; N476-F479 WeakPolarHBondContact O-CB 3.35Å; N476-F479 PolarHBondContact O-N 3.48Å
477P92.8Very high92.3Very high24 Ų2462.7 Ų62.716%0.15633%0.326CS..THydrogen-bonded Turntrans-67.6-18.2179.928.8-36.5000113.6R475 V520 I521 K524R475-P477 WeakPolarHBondContact O-CD 3.39Å; P477-V520 HydrophobicContact CB-CG1 4.19Å; P477-V520 HydrophobicContact CG-CB 4.33Å; P477-V520 HydrophobicContact CG-CG1 3.57Å; P477-I521 HydrophobicContact CB-CG1 4.48Å; P477-I521 HydrophobicContact CG-CG1 3.81Å; P477-K524 HydrophobicContact CB-CB 3.65Å; P477-K524 HydrophobicContact CB-CG 3.73Å
478L92.9Very high92.4Very high88 Ų8862.7 Ų62.746%0.46133%0.326SS..THydrogen-bonded Turntrans-89.9-6.1179.3-56.7-179.3000113.1P414 T415 N476 N480 V520P414-L478 HydrophobicContact CB-CD1 4.42Å; T415-L478 HydrophobicContact CG2-CB 4.26Å; N476-L478 PolarHBondContact O-N 3.25Å; N476-L478 WeakPolarHBondContact OD1-CB 3.35Å; N476-L478 PolarHBondContact OD1-N 3.15Å; L478-N480 PolarHBondContact O-N 3.18Å; L478-V520 HydrophobicContact CD2-CG1 4Å; L478-V520 HydrophobicContact CG-CG1 4.38Å
479F95.4Very high92.7Very high27 Ų2767 Ų6712%0.11833%0.334CS..  trans-69.2127.8-179.9179.5-112.6000111.8F417 E418 N476 V484F417-F479 WeakPolarHBondContact O-CB 3.5Å; F417-F479 WeakPolarHBondContact O-CD2 3.46Å; E418-F479 VanDerWaalsContact CA-CG 3.44Å; E418-F479 HydrophobicContact CB-CD1 3.72Å; E418-F479 HydrophobicContact CB-CD2 4.24Å; E418-F479 HydrophobicContact CB-CE1 3.67Å; E418-F479 HydrophobicContact CB-CE2 4.18Å; E418-F479 HydrophobicContact CB-CG 4Å; E418-F479 HydrophobicContact CB-CZ 3.91Å; E418-F479 HydrophobicContact CG-CD1 3.75Å; E418-F479 HydrophobicContact CG-CE1 3.8Å; E418-F479 HydrophobicContact CG-CG 4.42Å; N476-F479 HydrophobicContact CB-CB 4.17Å; N476-F479 WeakPolarHBondContact O-CB 3.35Å; N476-F479 PolarHBondContact O-N 3.48Å; F479-V484 HydrophobicContact CD2-CG1 4.37Å; F479-V484 HydrophobicContact CE2-CG1 3.65Å; F479-V484 HydrophobicContact CZ-CG1 4.28Å
480N90.4Very high93.2Very high77 Ų7761.9 Ų61.941%0.41232%0.316SS..  trans-127.4105.4173.6-177.1-8.4000110.3L478 N482 N483 V484L478-N480 PolarHBondContact O-N 3.18Å; N480-N482 PolarHBondContact O-N 3.26Å; N480-N482 VanDerWaalsContact O-N 3.08Å; N480-N482 WeakPolarHBondContact OD1-CB 3.14Å; N480-N482 PolarHBondContact OD1-N 3.11Å; N480-N483 HydrophobicContact CB-CB 4.46Å; N480-N483 CarbonylContact O-C 3.56Å; N480-N483 PolarHBondContact O-N 3.33Å; N480-V484 WeakPolarHBondContact O-CG1 3.43Å
481S91.7Very high93.6Very high76 Ų7661.4 Ų61.453%0.53132%0.316SS..G310 helixtrans-58.4-24-178.955.50000114.3N483S481-N483 VanDerWaalsContact C-N 3.32Å
482N92.3Very high94.2Very high150 Ų15058 Ų5880%0.80230%0.303SS*.G310 helixtrans-83.7-11-179.2-61.1-22.7000112.8N480N480-N482 PolarHBondContact O-N 3.26Å; N480-N482 VanDerWaalsContact O-N 3.08Å; N480-N482 WeakPolarHBondContact OD1-CB 3.14Å; N480-N482 PolarHBondContact OD1-N 3.11Å
483N92.2Very high94.9Very high120 Ų12061.9 Ų61.964%0.64232%0.316SS*.G310 helixtrans-134.946.6-173.6-164.727.4000111.3N480 S481N480-N483 HydrophobicContact CB-CB 4.46Å; N480-N483 CarbonylContact O-C 3.56Å; N480-N483 PolarHBondContact O-N 3.33Å; S481-N483 VanDerWaalsContact C-N 3.32Å
484V95.2Very high95.3Very high35 Ų3565.8 Ų65.821%0.21234%0.342CS..  trans-99.6137.9173-65.10000111.1P357 E416 F479 N480P357-V484 HydrophobicContact CB-CG2 4.03Å; E416-V484 WeakPolarHBondContact OE2-CA 3.2Å; E416-V484 WeakPolarHBondContact OE2-CB 3.45Å; F479-V484 HydrophobicContact CD2-CG1 4.37Å; F479-V484 HydrophobicContact CE2-CG1 3.65Å; F479-V484 HydrophobicContact CZ-CG1 4.28Å; N480-V484 WeakPolarHBondContact O-CG1 3.43Å
485S96.2Very high95.4Very high55 Ų5571.5 Ų71.539%0.38537%0.369SS..  trans-69.2138.9177.6-59.10000110.6P357 R360 E416 L487P357-S485 WeakPolarHBondContact CG-O 3.21Å; R360-S485 PolarHBondContact NH1-O 2.84Å; E416-S485 VanDerWaalsContact CD-N 3.28Å; E416-S485 WeakPolarHBondContact OE1-CB 3.18Å; E416-S485 PolarHBondContact OE1-N 3.29Å; E416-S485 PolarHBondContact OE1-OG 3.04Å; E416-S485 PolarHBondContact OE2-N 3.36Å; S485-L487 VanDerWaalsContact C-N 3.34Å; S485-L487 PolarHBondContact O-N 3.17Å
486Q95.1Very high95.5Very high107 Ų10771.1 Ų71.150%0.537%0.37SS..SBendtrans-66.2-36.9178.3-70.9-66.3-5700112.9
487L97.8Very high95.6Very high58 Ų5871.1 Ų71.130%0.30437%0.37SS..SBendtrans-128.2142.9179.3-67.3174.8000108.7Y194 L354 L355 S485Y194-L487 HydrophobicContact CE2-CD2 4.35Å; Y194-L487 WeakPolarHBondContact OH-CD2 3.25Å; L354-L487 WeakPolarHBondContact O-CA 3.46Å; L355-L487 HydrophobicContact CD2-CD2 3.94Å; S485-L487 VanDerWaalsContact C-N 3.34Å; S485-L487 PolarHBondContact O-N 3.17Å
488L98.5Very high95.8Very high5 Ų572.7 Ų72.73%0.02638%0.379CS..  trans-108.3140.4167.8-62.1177.9000110.3L354 R360 F413 E416 F417L354-L488 HydrophobicContact CD2-CB 3.76Å; L354-L488 PolarHBondContact O-N 3.2Å; R360-L488 VanDerWaalsContact CZ-CD1 3.47Å; R360-L488 VanDerWaalsContact NE-CD1 3.31Å; F413-L488 HydrophobicContact CB-CD1 4.45Å; F413-L488 HydrophobicContact CD1-CD2 3.8Å; F413-L488 HydrophobicContact CD2-CB 4.49Å; F413-L488 HydrophobicContact CD2-CD1 3.84Å; F413-L488 HydrophobicContact CD2-CD2 4.33Å; F413-L488 HydrophobicContact CD2-CG 4.42Å; F413-L488 HydrophobicContact CE1-CD2 3.99Å; F413-L488 HydrophobicContact CE2-CB 4.11Å; F413-L488 HydrophobicContact CE2-CD1 4.28Å; F413-L488 HydrophobicContact CG-CD1 4.09Å; F413-L488 HydrophobicContact CG-CD2 3.99Å; F413-L488 HydrophobicContact CZ-CB 4.2Å; F413-L488 HydrophobicContact CZ-CD2 4.36Å; E416-L488 HydrophobicContact CB-CD1 4.36Å; E416-L488 HydrophobicContact CB-CD2 4.48Å; E416-L488 HydrophobicContact CG-CD2 3.87Å; F417-L488 HydrophobicContact CE2-CD1 4.11Å; F417-L488 HydrophobicContact CZ-CD1 4.14Å
489K98.3Very high95.9Very high146 Ų14669.7 Ų69.764%0.63536%0.364SS*.  trans-122.296.5173.3-68.1-169.1176.9-163.20108
490P98.3Very high95.8Very high11 Ų1168.4 Ų68.47%0.07136%0.358CS..  trans-64.9146.8-177.327.5-33.4000111L354 L409 F413 L492L354-P490 HydrophobicContact CD1-CG 4.23Å; L354-P490 HydrophobicContact CD2-CG 4.25Å; L409-P490 HydrophobicContact CD2-CB 3.7Å; L409-P490 HydrophobicContact CD2-CG 4.26Å; F413-P490 HydrophobicContact CE2-CB 4.42Å; P490-L492 HydrophobicContact CB-CD2 4.36Å; P490-L492 HydrophobicContact CG-CD2 4.19Å; P490-L492 PolarHBondContact O-N 3.39Å
491D98.5Very high95.8Very high49 Ų4972.6 Ų72.626%0.26237%0.368SS..  trans-83112.1171.2-170.2-17.7000109.6Q412 R493 Q496Q412-D491 PolarHBondContact NE2-O 3.24Å; D491-R493 VanDerWaalsContact OD1-CB 3.27Å; D491-R493 WeakPolarHBondContact OD1-CB 3.39Å; D491-R493 WeakPolarHBondContact OD1-CG 3.5Å; D491-R493 PolarHBondContact OD1-N 2.99Å; D491-R493 IonicContact OD1-NE 2.61Å; D491-R493 PolarHBondContact OD1-NE 3.32Å; D491-R493 IonicContact OD2-CZ 3.46Å; D491-R493 IonicContact OD2-NE 3.54Å; D491-R493 PolarHBondContact OD2-NE 3.15Å; D491-R493 IonicContact OD2-NH2 2.85Å; D491-R493 PolarHBondContact OD2-NH2 3.4Å; D491-Q496 HydrophobicContact CB-CB 4.38Å; D491-Q496 HydrophobicContact CB-CG 4.01Å
492L98.4Very high95.5Very high34 Ų3470.7 Ų70.718%0.17836%0.355CS..  trans-94.49.5-175.4-57.2175.8000113.1R314 L317 E318 P490R314-L492 PolarHBondContact NE-O 3.44Å; L317-L492 HydrophobicContact CB-CD2 3.59Å; E318-L492 HydrophobicContact CB-CD1 4.01Å; E318-L492 HydrophobicContact CG-CD1 4.26Å; P490-L492 HydrophobicContact CB-CD2 4.36Å; P490-L492 HydrophobicContact CG-CD2 4.19Å; P490-L492 PolarHBondContact O-N 3.39Å
493R98.3Very high95.4Very high133 Ų13363.6 Ų63.650%0.50232%0.317SS..SBendtrans-61.4136.1172.9-70179.6-64.2170.52.3109.3D491 Q495 Q496D491-R493 VanDerWaalsContact OD1-CB 3.27Å; D491-R493 WeakPolarHBondContact OD1-CB 3.39Å; D491-R493 WeakPolarHBondContact OD1-CG 3.5Å; D491-R493 PolarHBondContact OD1-N 2.99Å; D491-R493 IonicContact OD1-NE 2.61Å; D491-R493 PolarHBondContact OD1-NE 3.32Å; D491-R493 IonicContact OD2-CZ 3.46Å; D491-R493 IonicContact OD2-NE 3.54Å; D491-R493 PolarHBondContact OD2-NE 3.15Å; D491-R493 IonicContact OD2-NH2 2.85Å; D491-R493 PolarHBondContact OD2-NH2 3.4Å; R493-Q495 PolarHBondContact O-N 2.79Å; R493-Q496 HydrophobicContact CB-CG 4.19Å; R493-Q496 WeakPolarHBondContact O-CB 3.38Å; R493-Q496 PolarHBondContact O-N 3.01Å
494P95.9Very high95.4Very high97 Ų9757.9 Ų57.963%0.6329%0.286SS*.G310 helixtrans-53.5-35.2-172-29.435.9000115.2Q496 I497P494-Q496 PolarHBondContact O-N 2.97Å; P494-I497 PolarHBondContact O-N 3.09Å
495Q95.1Very high94.8Very high122 Ų12257.1 Ų57.157%0.5728%0.281SS*.G310 helixtrans-69.8-12.4178.567.8-88.43000114.6R493R493-Q495 PolarHBondContact O-N 2.79Å
496Q96.9Very high93.9Very high69 Ų6956.3 Ų56.332%0.32227%0.269SS..G310 helixtrans-90.8-6.9175.7-57.5-60.9-23.200112.6Q412 D491 R493 P494Q412-Q496 PolarHBondContact NE2-O 2.96Å; D491-Q496 HydrophobicContact CB-CB 4.38Å; D491-Q496 HydrophobicContact CB-CG 4.01Å; R493-Q496 HydrophobicContact CB-CG 4.19Å; R493-Q496 WeakPolarHBondContact O-CB 3.38Å; R493-Q496 PolarHBondContact O-N 3.01Å; P494-Q496 PolarHBondContact O-N 2.97Å
497I98Very high92.8Very high11 Ų1155.7 Ų55.76%0.05626%0.263CS..SBendtrans-101108.1177.1-50.2-57.3000107.7L310 I313 R314 L317 P494L310-I497 HydrophobicContact CB-CG2 4.15Å; L310-I497 HydrophobicContact CD2-CG2 4.39Å; I313-I497 HydrophobicContact CB-CG2 4.35Å; I313-I497 HydrophobicContact CG2-CG2 4.22Å; R314-I497 HydrophobicContact CB-CG1 4.11Å; R314-I497 HydrophobicContact CG-CG1 4.18Å; L317-I497 HydrophobicContact CD1-CD1 3.88Å; P494-I497 PolarHBondContact O-N 3.09Å
498T95.8Very high91.6Very high57 Ų5755.6 Ų55.635%0.3526%0.263SS..  trans-116158.1-166.865.40000112L310 W407 Q408 W500L310-T498 WeakPolarHBondContact CD2-O 3.37Å; W407-T498 WeakPolarHBondContact CH2-OG1 3.23Å; W407-T498 WeakPolarHBondContact CZ3-OG1 3.45Å; Q408-T498 PolarHBondContact NE2-O 3.24Å; T498-W500 PolarHBondContact O-N 3.18Å
499L95.3Very high89.8Confident24 Ų2457.9 Ų57.913%0.12627%0.274CS..  trans-71.1124.7174.817566.2000109.4M285 V289 F300 M304 R501 Y504M285-L499 HydrophobicContact CE-CD1 4.42Å; M285-L499 HydrophobicContact SD-CD1 3.65Å; V289-L499 HydrophobicContact CG2-CD1 4.36Å; V289-L499 HydrophobicContact CG2-CD2 3.77Å; F300-L499 HydrophobicContact CZ-CD2 4.44Å; M304-L499 HydrophobicContact CE-CB 4.39Å; M304-L499 HydrophobicContact CE-CD1 4.06Å; M304-L499 HydrophobicContact CE-CD2 4.43Å; L499-R501 VanDerWaalsContact C-N 3.26Å; L499-R501 HydrophobicContact CD2-CG 4.3Å; L499-R501 HydrophobicContact CG-CG 4.3Å; L499-R501 PolarHBondContact O-N 2.79Å; L499-Y504 HydrophobicContact CD1-CD2 3.61Å; L499-Y504 HydrophobicContact CD1-CE2 4.26Å; L499-Y504 HydrophobicContact CD1-CG 4.41Å
500W94.4Very high87.9Confident0 Ų054.1 Ų54.10%027%0.267CS..  trans-72.677174.4-170.97.1000112L403 D404 W407 E421 L424 I425 T498 S502 L503 Y504L403-W500 HydrophobicContact CB-CH2 4.41Å; L403-W500 HydrophobicContact CB-CZ3 4.14Å; D404-W500 HydrophobicContact CB-CE3 3.84Å; D404-W500 HydrophobicContact CB-CZ3 4.2Å; W407-W500 HydrophobicContact CB-CD2 3.92Å; W407-W500 HydrophobicContact CB-CE3 3.9Å; W407-W500 HydrophobicContact CB-CH2 3.9Å; W407-W500 HydrophobicContact CB-CZ2 3.87Å; W407-W500 HydrophobicContact CB-CZ3 3.91Å; W407-W500 AromaticContact CD1-CD1 3.94Å; W407-W500 AromaticContact CD1-CE2 3.45Å; W407-W500 VanDerWaalsContact CD1-CE2 3.45Å; W407-W500 AromaticContact CD1-CZ2 3.7Å; W407-W500 AromaticContact CD1-NE1 3.39Å; W407-W500 HydrophobicContact CD2-CB 3.99Å; W407-W500 AromaticContact CD2-CD1 3.56Å; W407-W500 AromaticContact CD2-CD2 3.78Å; W407-W500 HydrophobicContact CD2-CD2 3.78Å; W407-W500 AromaticContact CD2-CE2 3.93Å; W407-W500 HydrophobicContact CD2-CE3 4.48Å; W407-W500 AromaticContact CD2-CG 3.54Å; W407-W500 HydrophobicContact CD2-CG 3.54Å; W407-W500 AromaticContact CD2-NE1 3.81Å; W407-W500 AromaticContact CE2-CD1 3.3Å; W407-W500 AromaticContact CE2-CG 3.79Å; W407-W500 AromaticContact CE2-NE1 3.57Å; W407-W500 HydrophobicContact CE3-CB 3.66Å; W407-W500 HydrophobicContact CE3-CD2 4.22Å; W407-W500 AromaticContact CE3-CG 3.77Å; W407-W500 HydrophobicContact CE3-CG 3.77Å; W407-W500 AromaticContact CG-CD1 3.95Å; W407-W500 AromaticContact CG-CD2 3.63Å; W407-W500 HydrophobicContact CG-CD2 3.63Å; W407-W500 AromaticContact CG-CE2 3.45Å; W407-W500 VanDerWaalsContact CG-CE2 3.45Å; W407-W500 HydrophobicContact CG-CE3 4.14Å; W407-W500 AromaticContact CG-CG 3.94Å; W407-W500 HydrophobicContact CG-CG 3.94Å; W407-W500 HydrophobicContact CG-CH2 4.33Å; W407-W500 AromaticContact CG-CZ2 3.81Å; W407-W500 HydrophobicContact CG-CZ2 3.81Å; W407-W500 HydrophobicContact CG-CZ3 4.47Å; W407-W500 AromaticContact CG-NE1 3.69Å; W407-W500 HydrophobicContact CH2-CB 4.16Å; W407-W500 HydrophobicContact CH2-CG 4.41Å; W407-W500 HydrophobicContact CZ2-CB 4.43Å; W407-W500 AromaticContact CZ2-CD1 3.67Å; W407-W500 HydrophobicContact CZ2-CG 4.21Å; W407-W500 HydrophobicContact CZ3-CB 3.77Å; W407-W500 HydrophobicContact CZ3-CG 4.2Å; W407-W500 AromaticContact NE1-CD1 3.55Å; W407-W500 AromaticContact NE1-CE2 3.86Å; W407-W500 AromaticContact NE1-NE1 3.29Å; E421-W500 HydrophobicContact CG-CZ2 4.03Å; E421-W500 PolarHBondContact OE1-NE1 2.94Å; L424-W500 HydrophobicContact CB-CH2 3.64Å; L424-W500 HydrophobicContact CB-CZ2 4.02Å; L424-W500 HydrophobicContact CD1-CH2 4.31Å; I425-W500 HydrophobicContact CD1-CZ2 4.26Å; I425-W500 HydrophobicContact CG1-CH2 4.27Å; I425-W500 HydrophobicContact CG1-CZ2 3.54Å; T498-W500 PolarHBondContact O-N 3.18Å; W500-S502 PolarHBondContact O-N 3.1Å; W500-L503 HydrophobicContact CB-CB 4.42Å; W500-L503 HydrophobicContact CD2-CB 3.49Å; W500-L503 VanDerWaalsContact CD2-CB 3.49Å; W500-L503 HydrophobicContact CD2-CD2 3.87Å; W500-L503 HydrophobicContact CD2-CG 4.31Å; W500-L503 HydrophobicContact CE3-CB 3.9Å; W500-L503 HydrophobicContact CE3-CD2 3.31Å; W500-L503 HydrophobicContact CE3-CG 4.22Å; W500-L503 HydrophobicContact CG-CB 3.7Å; W500-L503 HydrophobicContact CH2-CD2 4.16Å; W500-L503 HydrophobicContact CZ2-CB 4.35Å; W500-L503 HydrophobicContact CZ3-CB 4.45Å; W500-L503 HydrophobicContact CZ3-CD2 3.46Å; W500-L503 VanDerWaalsContact CZ3-CD2 3.46Å; W500-L503 HydrophobicContact CZ3-CG 4.49Å; W500-L503 PolarHBondContact O-N 3.21Å; W500-L503 VanDerWaalsContact O-N 3.17Å; W500-Y504 HydrophobicContact CB-CD2 4.02Å; W500-Y504 HydrophobicContact CB-CE2 3.88Å; W500-Y504 WeakPolarHBondContact O-CD2 3.17Å; W500-Y504 PolarHBondContact O-N 3.29Å
501R88.6Confident85.9Confident166 Ų16656.3 Ų56.363%0.62628%0.282SS*.Hα-helixtrans-58.6-43.1-173.3-64.2179.9-173.1178.41.2112.5L499 L503 Y504 N505L499-R501 VanDerWaalsContact C-N 3.26Å; L499-R501 HydrophobicContact CD2-CG 4.3Å; L499-R501 HydrophobicContact CG-CG 4.3Å; L499-R501 PolarHBondContact O-N 2.79Å; R501-L503 PolarHBondContact O-N 2.79Å; R501-L503 VanDerWaalsContact O-N 3.15Å; R501-Y504 PolarHBondContact O-N 3.31Å; R501-N505 WeakPolarHBondContact O-CA 3.13Å; R501-N505 VanDerWaalsContact O-CB 3.25Å; R501-N505 WeakPolarHBondContact O-CB 3.23Å; R501-N505 PolarHBondContact O-N 3.46Å
502S86.3Confident84.1Confident36 Ų3658.3 Ų58.325%0.25229%0.286SS..Hα-helixtrans-60.1-28.5-179-47.30000113.2E421 W500 R506E421-S502 WeakPolarHBondContact OE1-CB 3.5Å; E421-S502 PolarHBondContact OE1-OG 2.98Å; E421-S502 PolarHBondContact OE2-OG 2.72Å; W500-S502 PolarHBondContact O-N 3.1Å; S502-R506 WeakPolarHBondContact O-CB 3.38Å
503L90.9Very high82.1Confident0 Ų064.6 Ų64.60%031%0.314CS..Hα-helixtrans-84.9-50.4174.6179.364.4000112.1F76 T400 I425 Q428 W500 R501 R506F76-L503 HydrophobicContact CD2-CD1 4.1Å; F76-L503 HydrophobicContact CD2-CG 3.97Å; F76-L503 HydrophobicContact CE2-CD1 4.1Å; F76-L503 HydrophobicContact CE2-CD2 4.03Å; F76-L503 HydrophobicContact CE2-CG 3.85Å; T400-L503 HydrophobicContact CG2-CD2 4.24Å; I425-L503 HydrophobicContact CG1-CD1 4.46Å; Q428-L503 HydrophobicContact CB-CD1 4.28Å; Q428-L503 HydrophobicContact CG-CD1 3.96Å; Q428-L503 HydrophobicContact CG-CD2 4.46Å; W500-L503 HydrophobicContact CB-CB 4.42Å; W500-L503 HydrophobicContact CD2-CB 3.49Å; W500-L503 VanDerWaalsContact CD2-CB 3.49Å; W500-L503 HydrophobicContact CD2-CD2 3.87Å; W500-L503 HydrophobicContact CD2-CG 4.31Å; W500-L503 HydrophobicContact CE3-CB 3.9Å; W500-L503 HydrophobicContact CE3-CD2 3.31Å; W500-L503 HydrophobicContact CE3-CG 4.22Å; W500-L503 HydrophobicContact CG-CB 3.7Å; W500-L503 HydrophobicContact CH2-CD2 4.16Å; W500-L503 HydrophobicContact CZ2-CB 4.35Å; W500-L503 HydrophobicContact CZ3-CB 4.45Å; W500-L503 HydrophobicContact CZ3-CD2 3.46Å; W500-L503 VanDerWaalsContact CZ3-CD2 3.46Å; W500-L503 HydrophobicContact CZ3-CG 4.49Å; W500-L503 PolarHBondContact O-N 3.21Å; W500-L503 VanDerWaalsContact O-N 3.17Å; R501-L503 PolarHBondContact O-N 2.79Å; R501-L503 VanDerWaalsContact O-N 3.15Å; L503-R506 VanDerWaalsContact O-CB 3.26Å; L503-R506 WeakPolarHBondContact O-CB 3.36Å
504Y91.5Very high80.1Confident0 Ų061.5 Ų61.50%031%0.308CS..Hα-helixtrans-85.4-25.3-170.4-61.1-58.8000114.4F76 L282 M285 L286 W290 W309 D404 L499 W500 R501F76-Y504 AromaticContact CD2-CD1 3.71Å; F76-Y504 HydrophobicContact CD2-CD1 3.71Å; F76-Y504 HydrophobicContact CD2-CE1 4.08Å; F76-Y504 HydrophobicContact CE1-CD1 4.48Å; F76-Y504 HydrophobicContact CE1-CE1 4.41Å; F76-Y504 AromaticContact CE2-CD1 3.6Å; F76-Y504 HydrophobicContact CE2-CD1 3.6Å; F76-Y504 AromaticContact CE2-CE1 3.47Å; F76-Y504 HydrophobicContact CE2-CE1 3.47Å; F76-Y504 VanDerWaalsContact CE2-CE1 3.47Å; F76-Y504 HydrophobicContact CG-CD1 4.19Å; F76-Y504 HydrophobicContact CZ-CD1 4.02Å; F76-Y504 AromaticContact CZ-CE1 3.67Å; F76-Y504 HydrophobicContact CZ-CE1 3.67Å; L282-Y504 HydrophobicContact CD1-CD1 4.45Å; L282-Y504 HydrophobicContact CD1-CE1 3.73Å; M285-Y504 HydrophobicContact CE-CD1 3.53Å; M285-Y504 HydrophobicContact CE-CD2 3.79Å; M285-Y504 HydrophobicContact CE-CE1 3.67Å; M285-Y504 HydrophobicContact CE-CE2 3.92Å; M285-Y504 HydrophobicContact CE-CG 3.6Å; M285-Y504 HydrophobicContact SD-CD2 4.49Å; M285-Y504 HydrophobicContact SD-CG 4.42Å; L286-Y504 HydrophobicContact CD2-CD1 3.87Å; W290-Y504 PolarHBondContact NE1-O 3.2Å; W309-Y504 VanDerWaalsContact CE2-OH 3.3Å; W309-Y504 WeakPolarHBondContact CZ2-OH 3.12Å; W309-Y504 AromaticContact NE1-CE2 3.85Å; W309-Y504 AromaticContact NE1-CZ 3.74Å; W309-Y504 PolarHBondContact NE1-OH 3.07Å; D404-Y504 WeakPolarHBondContact OD2-CE2 3.46Å; D404-Y504 PolarHBondContact OD2-OH 2.87Å; D404-Y504 VanDerWaalsContact OD2-OH 3.05Å; L499-Y504 HydrophobicContact CD1-CD2 3.61Å; L499-Y504 HydrophobicContact CD1-CE2 4.26Å; L499-Y504 HydrophobicContact CD1-CG 4.41Å; W500-Y504 HydrophobicContact CB-CD2 4.02Å; W500-Y504 HydrophobicContact CB-CE2 3.88Å; W500-Y504 WeakPolarHBondContact O-CD2 3.17Å; W500-Y504 PolarHBondContact O-N 3.29Å; R501-Y504 PolarHBondContact O-N 3.31Å
505N83Confident78.8Confident19 Ų1959.2 Ų59.210%0.10229%0.29CS..THydrogen-bonded Turntrans-100.216.1171.5-64.590.3000111.7V289 R501 Y507 D508 C511V289-N505 VanDerWaalsContact CG1-ND2 3.29Å; V289-N505 WeakPolarHBondContact CG1-ND2 3.47Å; V289-N505 WeakPolarHBondContact CG1-OD1 3.3Å; R501-N505 WeakPolarHBondContact O-CA 3.13Å; R501-N505 VanDerWaalsContact O-CB 3.25Å; R501-N505 WeakPolarHBondContact O-CB 3.23Å; R501-N505 PolarHBondContact O-N 3.46Å; N505-Y507 PolarHBondContact O-N 3.44Å; N505-D508 HydrophobicContact CB-CB 4.21Å; N505-D508 WeakPolarHBondContact O-CB 3.36Å; N505-D508 PolarHBondContact O-N 3.13Å; N505-C511 HydrophobicContact CB-CB 4.26Å
506R76Confident78.1Confident39 Ų3960 Ų6015%0.14730%0.297CS..THydrogen-bonded Turntrans-51.7-38.5-174.1-166.9176.5-151.2-152.9-13.8112.7I425 E429 S502 L503 R512I425-R506 VanDerWaalsContact CG2-NE 3.31Å; E429-R506 IonicContact OE2-CZ 3.24Å; E429-R506 IonicContact OE2-NH1 3.73Å; E429-R506 PolarHBondContact OE2-NH1 2.86Å; E429-R506 IonicContact OE2-NH2 3.82Å; E429-R506 PolarHBondContact OE2-NH2 3Å; S502-R506 WeakPolarHBondContact O-CB 3.38Å; L503-R506 VanDerWaalsContact O-CB 3.26Å; L503-R506 WeakPolarHBondContact O-CB 3.36Å; R506-R512 PolarHBondContact O-NE 3.17Å; R506-R512 PolarHBondContact O-NH2 3.46Å
507Y73.9Confident77.5Confident94 Ų9458.2 Ų58.237%0.36929%0.289SS..THydrogen-bonded Turntrans-98.63.6-179.3-62.5-90.7000114.2T75 F77 N505 I509T75-Y507 VanDerWaalsContact O-CE2 3.23Å; T75-Y507 WeakPolarHBondContact O-CE2 3.31Å; F77-Y507 VanDerWaalsContact CA-CD2 3.46Å; F77-Y507 HydrophobicContact CB-CD1 3.63Å; F77-Y507 HydrophobicContact CB-CD2 3.36Å; F77-Y507 HydrophobicContact CB-CE1 3.82Å; F77-Y507 HydrophobicContact CB-CE2 3.59Å; F77-Y507 HydrophobicContact CB-CG 3.37Å; F77-Y507 HydrophobicContact CD1-CE2 4.41Å; N505-Y507 PolarHBondContact O-N 3.44Å; Y507-I509 PolarHBondContact O-N 2.85Å
508D70.7Confident76.8Confident55 Ų5557.9 Ų57.929%0.29429%0.288SS..  trans-81.698.9172.8-174.6-8.8000109.9N505 S510 C511N505-D508 HydrophobicContact CB-CB 4.21Å; N505-D508 WeakPolarHBondContact O-CB 3.36Å; N505-D508 PolarHBondContact O-N 3.13Å; D508-S510 PolarHBondContact O-N 3.49Å; D508-S510 WeakPolarHBondContact OD1-CA 3.48Å; D508-S510 WeakPolarHBondContact OD1-CB 3.5Å; D508-S510 PolarHBondContact OD1-N 3.45Å; D508-S510 PolarHBondContact OD1-OG 3.2Å; D508-C511 HydrophobicContact CB-CB 4.09Å; D508-C511 PolarHBondContact O-N 3.43Å; D508-C511 VanDerWaalsContact O-N 3.16Å
509I61.1Low76.3Confident53 Ų5357.1 Ų57.127%0.27228%0.283SS..G310 helixtrans-55.2-33.1177.9-65.1172.8000111.3Y507 C511 P626Y507-I509 PolarHBondContact O-N 2.85Å; I509-C511 VanDerWaalsContact C-N 3.32Å; I509-C511 PolarHBondContact O-N 3.05Å; I509-P626 HydrophobicContact CG2-CG 4.27Å
510S58.4Low76Confident67 Ų6758 Ų5847%0.46929%0.289SS..G310 helixtrans-78.8-13.3-175.769.80000114.4K293 D508K293-S510 WeakPolarHBondContact CE-OG 3.2Å; D508-S510 PolarHBondContact O-N 3.49Å; D508-S510 WeakPolarHBondContact OD1-CA 3.48Å; D508-S510 WeakPolarHBondContact OD1-CB 3.5Å; D508-S510 PolarHBondContact OD1-N 3.45Å; D508-S510 PolarHBondContact OD1-OG 3.2Å
511C56.8Low75.8Confident58 Ų5858.1 Ų58.139%0.39229%0.29SS..G310 helixtrans-104.1-1.6-178.6-1660000113.4N505 D508 I509 E513N505-C511 HydrophobicContact CB-CB 4.26Å; D508-C511 HydrophobicContact CB-CB 4.09Å; D508-C511 PolarHBondContact O-N 3.43Å; D508-C511 VanDerWaalsContact O-N 3.16Å; I509-C511 VanDerWaalsContact C-N 3.32Å; I509-C511 PolarHBondContact O-N 3.05Å; C511-E513 PolarHBondContact O-N 2.9Å
512R61.3Low75.8Confident91 Ų9150.7 Ų50.734%0.34326%0.264SS..  trans-86.397.6-177.2-62.9-150.4-156.8-175.57.1111.7R506 P626R506-R512 PolarHBondContact O-NE 3.17Å; R506-R512 PolarHBondContact O-NH2 3.46Å; R512-P626 HydrophobicContact CB-CB 3.88Å; R512-P626 WeakPolarHBondContact CD-O 3.28Å; R512-P626 HydrophobicContact CG-CB 4.28Å; R512-P626 PolarHBondContact NE-O 3.33Å; R512-P626 PolarHBondContact NH1-O 3.1Å
513E54.9Low76Confident166 Ų16654.5 Ų54.578%0.77628%0.276SS*.  trans-73.1150.9157-70.3179.5169.200109.7C511 L515C511-E513 PolarHBondContact O-N 2.9Å; E513-L515 PolarHBondContact O-N 3.35Å
514D57.1Low76.1Confident68 Ų6858.3 Ų58.336%0.36429%0.293SS..  trans-55.9108.9167.1-90.8-38.1000107.7L516 S610 K630D514-L516 PolarHBondContact O-N 3.39Å; D514-S610 WeakPolarHBondContact OD2-CA 3.2Å; D514-S610 WeakPolarHBondContact OD2-CB 3.36Å; D514-K630 IonicContact OD1-NZ 3.49Å
515L67.9Low76.1Confident49 Ų4958.9 Ų58.926%0.25730%0.295SS..  trans-53.6121.6-174.8-12383.2000108.3E421 E513 L517 N518E421-L515 WeakPolarHBondContact OE2-CD2 3.29Å; E513-L515 PolarHBondContact O-N 3.35Å; L515-L517 HydrophobicContact CB-CB 4.28Å; L515-L517 HydrophobicContact CD2-CB 3.83Å; L515-L517 HydrophobicContact CD2-CD2 4.05Å; L515-L517 HydrophobicContact CG-CB 4.42Å; L515-L517 PolarHBondContact O-N 2.75Å; L515-N518 WeakPolarHBondContact O-CB 3.44Å; L515-N518 PolarHBondContact O-N 2.95Å
516L81Confident76.6Confident137 Ų13759.9 Ų59.972%0.71730%0.3SS*.Hα-helixtrans-42.7-37.8169.9174.562.2000111.1D514 N518 T519 V520D514-L516 PolarHBondContact O-N 3.39Å; L516-N518 PolarHBondContact O-N 2.73Å; L516-T519 WeakPolarHBondContact O-CB 3.25Å; L516-T519 PolarHBondContact O-N 2.95Å; L516-V520 HydrophobicContact CD1-CG2 4.08Å; L516-V520 HydrophobicContact CG-CG2 4.2Å; L516-V520 VanDerWaalsContact O-CG2 3.28Å; L516-V520 WeakPolarHBondContact O-CG2 3.5Å; L516-V520 PolarHBondContact O-N 3.35Å
517L83.9Confident77.4Confident32 Ų3262.5 Ų62.517%0.16832%0.316CS..Hα-helixtrans-53.3-44.3173.7-17761.3000114N420 E421 L515 T519 V520 I521N420-L517 HydrophobicContact CB-CD1 4.16Å; N420-L517 HydrophobicContact CB-CD2 4.13Å; E421-L517 HydrophobicContact CB-CD2 4.43Å; L515-L517 HydrophobicContact CB-CB 4.28Å; L515-L517 HydrophobicContact CD2-CB 3.83Å; L515-L517 HydrophobicContact CD2-CD2 4.05Å; L515-L517 HydrophobicContact CG-CB 4.42Å; L515-L517 PolarHBondContact O-N 2.75Å; L517-T519 VanDerWaalsContact C-N 3.33Å; L517-T519 PolarHBondContact O-N 3.23Å; L517-V520 PolarHBondContact O-N 2.98Å; L517-I521 HydrophobicContact CD1-CD1 3.96Å; L517-I521 HydrophobicContact CD1-CG1 4.16Å; L517-I521 HydrophobicContact CG-CD1 3.82Å; L517-I521 HydrophobicContact CG-CG1 4.41Å; L517-I521 WeakPolarHBondContact O-CB 3.43Å; L517-I521 WeakPolarHBondContact O-CG1 3.41Å; L517-I521 PolarHBondContact O-N 2.9Å
518N83.4Confident78.2Confident4 Ų460.1 Ų60.12%0.02131%0.309CS..Hα-helixtrans-62.5-44178.6-74.9-15.6000111.4R422 L515 L516 I521 A522 Y629R422-N518 PolarHBondContact NH2-OD1 3.18Å; L515-N518 WeakPolarHBondContact O-CB 3.44Å; L515-N518 PolarHBondContact O-N 2.95Å; L516-N518 PolarHBondContact O-N 2.73Å; N518-I521 PolarHBondContact O-N 3.3Å; N518-A522 WeakPolarHBondContact O-CB 3.46Å; N518-A522 PolarHBondContact O-N 3.14Å; N518-Y629 WeakPolarHBondContact OD1-CD2 3.35Å
519T85.8Confident79.2Confident42 Ų4257.5 Ų57.526%0.25830%0.295SS..Hα-helixtrans-63.3-45.2177.5-58.20000110.9L516 L517 A522 F523L516-T519 WeakPolarHBondContact O-CB 3.25Å; L516-T519 PolarHBondContact O-N 2.95Å; L517-T519 VanDerWaalsContact C-N 3.33Å; L517-T519 PolarHBondContact O-N 3.23Å; T519-A522 PolarHBondContact O-N 3.24Å; T519-F523 HydrophobicContact CG2-CD2 3.83Å; T519-F523 HydrophobicContact CG2-CE2 3.35Å; T519-F523 HydrophobicContact CG2-CZ 3.93Å; T519-F523 WeakPolarHBondContact O-CD2 3.5Å; T519-F523 WeakPolarHBondContact O-CG 3.17Å; T519-F523 PolarHBondContact O-N 2.98Å
520V89.4Confident80.8Confident41 Ų4157.4 Ų57.425%0.24830%0.295CS..Hα-helixtrans-65.4-41.7177.7178.50000111.6P477 L478 L516 L517 F523 K524P477-V520 HydrophobicContact CB-CG1 4.19Å; P477-V520 HydrophobicContact CG-CB 4.33Å; P477-V520 HydrophobicContact CG-CG1 3.57Å; L478-V520 HydrophobicContact CD2-CG1 4Å; L478-V520 HydrophobicContact CG-CG1 4.38Å; L516-V520 HydrophobicContact CD1-CG2 4.08Å; L516-V520 HydrophobicContact CG-CG2 4.2Å; L516-V520 VanDerWaalsContact O-CG2 3.28Å; L516-V520 WeakPolarHBondContact O-CG2 3.5Å; L516-V520 PolarHBondContact O-N 3.35Å; L517-V520 PolarHBondContact O-N 2.98Å; V520-F523 PolarHBondContact O-N 2.98Å; V520-K524 WeakPolarHBondContact O-CB 3.36Å; V520-K524 PolarHBondContact O-N 2.77Å
521I89.3Confident82.4Confident4 Ų457.1 Ų57.12%0.02129%0.293CS..Hα-helixtrans-60.3-49.1175-71.9168.7000110.2P477 L517 N518 F523 K524 Q525 Y629P477-I521 HydrophobicContact CB-CG1 4.48Å; P477-I521 HydrophobicContact CG-CG1 3.81Å; L517-I521 HydrophobicContact CD1-CD1 3.96Å; L517-I521 HydrophobicContact CD1-CG1 4.16Å; L517-I521 HydrophobicContact CG-CD1 3.82Å; L517-I521 HydrophobicContact CG-CG1 4.41Å; L517-I521 WeakPolarHBondContact O-CB 3.43Å; L517-I521 WeakPolarHBondContact O-CG1 3.41Å; L517-I521 PolarHBondContact O-N 2.9Å; N518-I521 PolarHBondContact O-N 3.3Å; I521-F523 PolarHBondContact O-N 2.79Å; I521-K524 PolarHBondContact O-N 3.41Å; I521-Q525 HydrophobicContact CG2-CG 4.32Å; I521-Q525 VanDerWaalsContact CG2-NE2 3.3Å; I521-Q525 WeakPolarHBondContact O-CB 3.46Å; I521-Q525 VanDerWaalsContact O-CG 3.29Å; I521-Q525 WeakPolarHBondContact O-CG 3.23Å; I521-Q525 PolarHBondContact O-N 3.12Å; I521-Y629 HydrophobicContact CD1-CE2 4.49Å; I521-Y629 HydrophobicContact CG2-CE2 4.13Å; I521-Y629 WeakPolarHBondContact CG2-OH 3.33Å
522A89.6Confident84Confident9 Ų956.4 Ų56.47%0.07429%0.288CS..Hα-helixtrans-59.9-45.2179.400000112N518 T519 Q525 Q526 V609N518-A522 WeakPolarHBondContact O-CB 3.46Å; N518-A522 PolarHBondContact O-N 3.14Å; T519-A522 PolarHBondContact O-N 3.24Å; A522-Q525 PolarHBondContact O-N 3.11Å; A522-Q526 WeakPolarHBondContact O-CB 3.31Å; A522-Q526 PolarHBondContact O-N 3.34Å; A522-V609 HydrophobicContact CB-CG2 3.59Å
523F91.1Very high85.5Confident116 Ų11653.1 Ų53.151%0.50928%0.277SS..Hα-helixtrans-63-43.3175.9-72-35.5000112.5T519 V520 I521 Q525 Q526 I527T519-F523 HydrophobicContact CG2-CD2 3.83Å; T519-F523 HydrophobicContact CG2-CE2 3.35Å; T519-F523 HydrophobicContact CG2-CZ 3.93Å; T519-F523 WeakPolarHBondContact O-CD2 3.5Å; T519-F523 WeakPolarHBondContact O-CG 3.17Å; T519-F523 PolarHBondContact O-N 2.98Å; V520-F523 PolarHBondContact O-N 2.98Å; I521-F523 PolarHBondContact O-N 2.79Å; F523-Q525 VanDerWaalsContact C-N 3.35Å; F523-Q525 PolarHBondContact O-N 2.58Å; F523-Q526 PolarHBondContact O-N 3.01Å; F523-I527 WeakPolarHBondContact O-CB 3.44Å; F523-I527 VanDerWaalsContact O-CG1 3.25Å; F523-I527 WeakPolarHBondContact O-CG1 3.24Å; F523-I527 PolarHBondContact O-N 3.41Å
524K91.5Very high87.3Confident81 Ų8149.8 Ų49.835%0.35226%0.264SS..Hα-helixtrans-61-45177.1177.555.6178.3153.50111.5P477 V520 I521 Q526 I527 D528P477-K524 HydrophobicContact CB-CB 3.65Å; P477-K524 HydrophobicContact CB-CG 3.73Å; V520-K524 WeakPolarHBondContact O-CB 3.36Å; V520-K524 PolarHBondContact O-N 2.77Å; I521-K524 PolarHBondContact O-N 3.41Å; K524-Q526 PolarHBondContact O-N 2.87Å; K524-I527 PolarHBondContact O-N 3.36Å; K524-D528 WeakPolarHBondContact CE-OD1 3.2Å; K524-D528 WeakPolarHBondContact CE-OD2 3.46Å; K524-D528 IonicContact NZ-OD1 2.91Å; K524-D528 PolarHBondContact NZ-OD1 3.01Å; K524-D528 IonicContact NZ-OD2 3.31Å; K524-D528 VanDerWaalsContact O-CG 3.24Å; K524-D528 PolarHBondContact O-N 3.35Å
525Q91.7Very high88.9Confident11 Ų1151 Ų515%0.05127%0.267CS..Hα-helixtrans-63.2-41.4177.4-70.9175.20.200112.2I521 A522 F523 D528 S529 W606 Y629 W634I521-Q525 HydrophobicContact CG2-CG 4.32Å; I521-Q525 VanDerWaalsContact CG2-NE2 3.3Å; I521-Q525 WeakPolarHBondContact O-CB 3.46Å; I521-Q525 VanDerWaalsContact O-CG 3.29Å; I521-Q525 WeakPolarHBondContact O-CG 3.23Å; I521-Q525 PolarHBondContact O-N 3.12Å; A522-Q525 PolarHBondContact O-N 3.11Å; F523-Q525 VanDerWaalsContact C-N 3.35Å; F523-Q525 PolarHBondContact O-N 2.58Å; Q525-D528 PolarHBondContact O-N 3.37Å; Q525-S529 WeakPolarHBondContact O-CB 3.15Å; Q525-S529 PolarHBondContact O-N 2.89Å; Q525-W606 HydrophobicContact CB-CH2 3.68Å; Q525-W606 HydrophobicContact CB-CZ3 3.82Å; Q525-Y629 PolarHBondContact NE2-OH 2.99Å; Q525-W634 HydrophobicContact CB-CH2 4.38Å; Q525-W634 HydrophobicContact CB-CZ2 3.66Å; Q525-W634 HydrophobicContact CG-CZ2 3.87Å
526Q93.1Very high90Very high41 Ų4149.1 Ų49.119%0.19226%0.257CS..Hα-helixtrans-63.3-44.1174.8-170.2-177.58.500111.4A522 F523 K524 D528 S529 L530 I604 W606A522-Q526 WeakPolarHBondContact O-CB 3.31Å; A522-Q526 PolarHBondContact O-N 3.34Å; F523-Q526 PolarHBondContact O-N 3.01Å; K524-Q526 PolarHBondContact O-N 2.87Å; Q526-D528 VanDerWaalsContact C-N 3.32Å; Q526-D528 PolarHBondContact O-N 3.42Å; Q526-S529 WeakPolarHBondContact O-CB 3.14Å; Q526-S529 PolarHBondContact O-N 3.06Å; Q526-L530 HydrophobicContact CG-CD1 4.14Å; Q526-L530 HydrophobicContact CG-CG 4.44Å; Q526-L530 WeakPolarHBondContact O-CB 3.44Å; Q526-L530 VanDerWaalsContact O-CG 3.29Å; Q526-L530 WeakPolarHBondContact O-CG 3.25Å; Q526-L530 PolarHBondContact O-N 3.27Å; Q526-I604 PolarHBondContact NE2-O 3.35Å; Q526-W606 HydrophobicContact CB-CD2 3.96Å; Q526-W606 HydrophobicContact CB-CE3 4.04Å; Q526-W606 HydrophobicContact CB-CG 4.42Å; Q526-W606 HydrophobicContact CB-CZ2 4.46Å; Q526-W606 HydrophobicContact CB-CZ3 4.34Å; Q526-W606 HydrophobicContact CG-CD2 4.02Å; Q526-W606 HydrophobicContact CG-CG 4.01Å
527I93.1Very high90.4Very high94 Ų9445 Ų4548%0.48224%0.236SC..Hα-helixtrans-58.9-44.7175.3-71.3164.9000110.7F523 K524 L530 S531F523-I527 WeakPolarHBondContact O-CB 3.44Å; F523-I527 VanDerWaalsContact O-CG1 3.25Å; F523-I527 WeakPolarHBondContact O-CG1 3.24Å; F523-I527 PolarHBondContact O-N 3.41Å; K524-I527 PolarHBondContact O-N 3.36Å; I527-L530 PolarHBondContact O-N 3.14Å; I527-S531 VanDerWaalsContact O-CB 3.31Å; I527-S531 WeakPolarHBondContact O-CB 3.37Å; I527-S531 PolarHBondContact O-N 3.4Å; I527-S531 PolarHBondContact O-OG 2.86Å
528D90.9Very high90.8Very high43 Ų4347.5 Ų47.523%0.2325%0.249CC..Hα-helixtrans-65.1-40.7179.3-70.2-17000111.9K524 Q525 Q526 S532 W634K524-D528 WeakPolarHBondContact CE-OD1 3.2Å; K524-D528 WeakPolarHBondContact CE-OD2 3.46Å; K524-D528 IonicContact NZ-OD1 2.91Å; K524-D528 PolarHBondContact NZ-OD1 3.01Å; K524-D528 IonicContact NZ-OD2 3.31Å; K524-D528 VanDerWaalsContact O-CG 3.24Å; K524-D528 PolarHBondContact O-N 3.35Å; Q525-D528 PolarHBondContact O-N 3.37Å; Q526-D528 VanDerWaalsContact C-N 3.32Å; Q526-D528 PolarHBondContact O-N 3.42Å; D528-S532 WeakPolarHBondContact O-CB 3.47Å; D528-S532 PolarHBondContact O-N 2.62Å; D528-S532 PolarHBondContact O-OG 2.94Å; D528-W634 HydrophobicContact CB-CH2 4.32Å
529S92.8Very high91.1Very high0 Ų050.1 Ų50.10%026%0.261CS..Hα-helixtrans-61.1-50.7173.7-170.10000111.2Q525 Q526 S531 S532 H533 H654Q525-S529 WeakPolarHBondContact O-CB 3.15Å; Q525-S529 PolarHBondContact O-N 2.89Å; Q526-S529 WeakPolarHBondContact O-CB 3.14Å; Q526-S529 PolarHBondContact O-N 3.06Å; S529-S531 VanDerWaalsContact C-N 3.34Å; S529-S531 PolarHBondContact O-N 3.5Å; S529-S532 PolarHBondContact O-N 3.46Å; S529-H533 WeakPolarHBondContact O-CB 3.32Å; S529-H533 PolarHBondContact O-N 3.16Å; S529-H654 PolarHBondContact O-NE2 2.82Å; S529-H654 PolarHBondContact OG-CE1 2.8Å; S529-H654 PolarHBondContact OG-NE2 2.82Å; S529-H654 VanDerWaalsContact OG-NE2 3.16Å
530L93.3Very high91.1Very high51 Ų5150.5 Ų50.527%0.26726%0.259SS..Hα-helixtrans-64.2-39.5-179.8-69.5175.6000111.9Q526 I527 H533 I534 I604Q526-L530 HydrophobicContact CG-CD1 4.14Å; Q526-L530 HydrophobicContact CG-CG 4.44Å; Q526-L530 WeakPolarHBondContact O-CB 3.44Å; Q526-L530 VanDerWaalsContact O-CG 3.29Å; Q526-L530 WeakPolarHBondContact O-CG 3.25Å; Q526-L530 PolarHBondContact O-N 3.27Å; I527-L530 PolarHBondContact O-N 3.14Å; L530-H533 PolarHBondContact O-N 3.36Å; L530-I534 VanDerWaalsContact O-CG1 3.27Å; L530-I534 WeakPolarHBondContact O-CG1 3.08Å; L530-I534 PolarHBondContact O-N 2.9Å; L530-I604 HydrophobicContact CD2-CG2 4.35Å
531S92.5Very high91.1Very high62 Ų6253.3 Ų53.343%0.43427%0.272SS..Hα-helixtrans-63.5-43.7178-57.50000111.3I527 S529 H533 I534 E535I527-S531 VanDerWaalsContact O-CB 3.31Å; I527-S531 WeakPolarHBondContact O-CB 3.37Å; I527-S531 PolarHBondContact O-N 3.4Å; I527-S531 PolarHBondContact O-OG 2.86Å; S529-S531 VanDerWaalsContact C-N 3.34Å; S529-S531 PolarHBondContact O-N 3.5Å; S531-H533 VanDerWaalsContact C-N 3.3Å; S531-H533 PolarHBondContact O-N 2.66Å; S531-I534 PolarHBondContact O-N 3.09Å; S531-E535 PolarHBondContact O-N 3.34Å
532S91.4Very high91.1Very high42 Ų4258.1 Ų58.129%0.29429%0.294SS..Hα-helixtrans-63.1-38.5175.5-56.10000111.7D528 S529 F536D528-S532 WeakPolarHBondContact O-CB 3.47Å; D528-S532 PolarHBondContact O-N 2.62Å; D528-S532 PolarHBondContact O-OG 2.94Å; S529-S532 PolarHBondContact O-N 3.46Å; S532-F536 WeakPolarHBondContact O-CB 3.3Å; S532-F536 PolarHBondContact O-N 3.36Å
533H91.9Very high91.1Very high22 Ų2264.7 Ų64.710%0.10232%0.321CS..Hα-helixtrans-69.8-39.8177.3-166.454.1000112.8S529 L530 S531 F536 L537 V602 G653S529-H533 WeakPolarHBondContact O-CB 3.32Å; S529-H533 PolarHBondContact O-N 3.16Å; L530-H533 PolarHBondContact O-N 3.36Å; S531-H533 VanDerWaalsContact C-N 3.3Å; S531-H533 PolarHBondContact O-N 2.66Å; H533-F536 WeakPolarHBondContact O-CB 3.5Å; H533-F536 PolarHBondContact O-N 2.97Å; H533-L537 WeakPolarHBondContact O-CB 3.47Å; H533-L537 VanDerWaalsContact O-CG 3.29Å; H533-L537 WeakPolarHBondContact O-CG 3.47Å; H533-L537 PolarHBondContact O-N 3.41Å; H533-V602 HydrophobicContact CB-CG1 4.22Å; H533-G653 PolarHBondContact ND1-O 3.23Å
534I91.9Very high90.9Very high97 Ų9763.9 Ų63.950%0.49732%0.321SS..Hα-helixtrans-60.6-46.5174.2-72.1164.2000110.3L530 S531 F536 L537 N538L530-I534 VanDerWaalsContact O-CG1 3.27Å; L530-I534 WeakPolarHBondContact O-CG1 3.08Å; L530-I534 PolarHBondContact O-N 2.9Å; S531-I534 PolarHBondContact O-N 3.09Å; I534-F536 VanDerWaalsContact C-N 3.33Å; I534-F536 PolarHBondContact O-N 3.02Å; I534-L537 PolarHBondContact O-N 3.33Å; I534-N538 WeakPolarHBondContact O-CB 3.26Å; I534-N538 VanDerWaalsContact O-CG 3.29Å; I534-N538 PolarHBondContact O-N 3.38Å; I534-N538 PolarHBondContact O-ND2 3.05Å
535E91.7Very high90.8Very high92 Ų9263 Ų6343%0.4332%0.323SS..Hα-helixtrans-58.8-46.4177.3179.855.9-150.700111.5S531 L537 N538 Q539S531-E535 PolarHBondContact O-N 3.34Å; E535-L537 PolarHBondContact O-N 2.84Å; E535-N538 PolarHBondContact O-N 3.43Å; E535-Q539 WeakPolarHBondContact O-CG 3.43Å; E535-Q539 PolarHBondContact O-N 3.47Å; E535-Q539 PolarHBondContact OE1-NE2 2.87Å
536F90.3Very high90.6Very high10 Ų1067.4 Ų67.44%0.04434%0.342CS..Hα-helixtrans-59.9-44.2175.8170.2-100.5000113.2S532 H533 I534 Q539 K540 T597 P652 G653 D655S532-F536 WeakPolarHBondContact O-CB 3.3Å; S532-F536 PolarHBondContact O-N 3.36Å; H533-F536 WeakPolarHBondContact O-CB 3.5Å; H533-F536 PolarHBondContact O-N 2.97Å; I534-F536 VanDerWaalsContact C-N 3.33Å; I534-F536 PolarHBondContact O-N 3.02Å; F536-Q539 PolarHBondContact O-N 3.43Å; F536-K540 HydrophobicContact CD1-CD 4.2Å; F536-K540 HydrophobicContact CE1-CD 3.7Å; F536-K540 VanDerWaalsContact CE1-NZ 3.32Å; F536-K540 HydrophobicContact CE2-CD 4.2Å; F536-K540 VanDerWaalsContact CE2-CE 3.43Å; F536-K540 HydrophobicContact CZ-CD 3.8Å; F536-K540 PolarHBondContact O-N 3.18Å; F536-K540 VanDerWaalsContact O-N 3.12Å; F536-T597 WeakPolarHBondContact CE1-O 3.39Å; F536-P652 WeakPolarHBondContact CE2-O 3.31Å; F536-P652 WeakPolarHBondContact CZ-O 3.46Å; F536-G653 WeakPolarHBondContact CB-O 3.21Å; F536-G653 VanDerWaalsContact CD1-O 3.32Å; F536-G653 WeakPolarHBondContact CD1-O 3.36Å; F536-G653 WeakPolarHBondContact CG-O 3.48Å; F536-D655 WeakPolarHBondContact CD2-O 3.25Å; F536-D655 HydrophobicContact CE2-CB 4.17Å
537L90.1Very high90.3Very high52 Ų5268 Ų6827%0.27235%0.354SS..Hα-helixtrans-65-40.8177.2-71.2175000111.6H533 I534 E535 Q539 K540 I541H533-L537 WeakPolarHBondContact O-CB 3.47Å; H533-L537 VanDerWaalsContact O-CG 3.29Å; H533-L537 WeakPolarHBondContact O-CG 3.47Å; H533-L537 PolarHBondContact O-N 3.41Å; I534-L537 PolarHBondContact O-N 3.33Å; E535-L537 PolarHBondContact O-N 2.84Å; L537-Q539 PolarHBondContact O-N 3.4Å; L537-K540 PolarHBondContact O-N 3.06Å; L537-I541 VanDerWaalsContact O-CG1 3.29Å; L537-I541 WeakPolarHBondContact O-CG1 3.42Å; L537-I541 PolarHBondContact O-N 2.92Å
538N91.6Very high89.9Confident84 Ų8470.1 Ų70.145%0.44936%0.362SS..Hα-helixtrans-60.3-45.6176.1-73.4-25.4000111.7I534 E535 K540 I541 E542I534-N538 WeakPolarHBondContact O-CB 3.26Å; I534-N538 VanDerWaalsContact O-CG 3.29Å; I534-N538 PolarHBondContact O-N 3.38Å; I534-N538 PolarHBondContact O-ND2 3.05Å; E535-N538 PolarHBondContact O-N 3.43Å; N538-K540 VanDerWaalsContact C-N 3.26Å; N538-K540 PolarHBondContact O-N 3.36Å; N538-I541 PolarHBondContact O-N 2.99Å; N538-E542 WeakPolarHBondContact O-CB 3.49Å; N538-E542 PolarHBondContact O-N 3.38Å
539Q89.5Confident89.4Confident58 Ų5873.5 Ų73.527%0.27138%0.376SS..Hα-helixtrans-61.2-35.7176.2-69.9176.514.700112.4E535 F536 L537 K543E535-Q539 WeakPolarHBondContact O-CG 3.43Å; E535-Q539 PolarHBondContact O-N 3.47Å; E535-Q539 PolarHBondContact OE1-NE2 2.87Å; F536-Q539 PolarHBondContact O-N 3.43Å; L537-Q539 PolarHBondContact O-N 3.4Å; Q539-K543 WeakPolarHBondContact O-CG 3.13Å; Q539-K543 PolarHBondContact O-N 2.57Å
540K86.9Confident88.8Confident50 Ų5078 Ų7822%0.21740%0.399CS..Hα-helixtrans-71.2-44.6175.8-76.9-177.4166.4-174.60112.4F536 L537 N538 E542 K543 L544 L596F536-K540 HydrophobicContact CD1-CD 4.2Å; F536-K540 HydrophobicContact CE1-CD 3.7Å; F536-K540 VanDerWaalsContact CE1-NZ 3.32Å; F536-K540 HydrophobicContact CE2-CD 4.2Å; F536-K540 VanDerWaalsContact CE2-CE 3.43Å; F536-K540 HydrophobicContact CZ-CD 3.8Å; F536-K540 PolarHBondContact O-N 3.18Å; F536-K540 VanDerWaalsContact O-N 3.12Å; L537-K540 PolarHBondContact O-N 3.06Å; N538-K540 VanDerWaalsContact C-N 3.26Å; N538-K540 PolarHBondContact O-N 3.36Å; K540-E542 VanDerWaalsContact C-N 3.29Å; K540-E542 PolarHBondContact O-N 3.18Å; K540-K543 PolarHBondContact O-N 2.6Å; K540-L544 WeakPolarHBondContact O-CG 3.34Å; K540-L544 PolarHBondContact O-N 3.3Å; K540-L596 WeakPolarHBondContact CD-O 3.28Å; K540-L596 WeakPolarHBondContact CE-O 3.49Å; K540-L596 PolarHBondContact NZ-O 3.48Å
541I89.1Confident88.1Confident101 Ų10179.1 Ų79.152%0.51841%0.411SS..Hα-helixtrans-59.1-43.6175.9-69.7165.4000110.1L537 N538 K543 L544 T545L537-I541 VanDerWaalsContact O-CG1 3.29Å; L537-I541 WeakPolarHBondContact O-CG1 3.42Å; L537-I541 PolarHBondContact O-N 2.92Å; N538-I541 PolarHBondContact O-N 2.99Å; I541-K543 PolarHBondContact O-N 3.07Å; I541-L544 PolarHBondContact O-N 2.96Å; I541-T545 WeakPolarHBondContact O-CB 3.1Å; I541-T545 PolarHBondContact O-N 3.35Å; I541-T545 PolarHBondContact O-OG1 3.21Å
542E90.1Very high87.3Confident104 Ų10478.7 Ų78.749%0.48641%0.408SS..Hα-helixtrans-62-43.1177.5-168.9-172.3167.400112.1N538 K540 T545 K546N538-E542 WeakPolarHBondContact O-CB 3.49Å; N538-E542 PolarHBondContact O-N 3.38Å; K540-E542 VanDerWaalsContact C-N 3.29Å; K540-E542 PolarHBondContact O-N 3.18Å; E542-T545 PolarHBondContact O-N 2.98Å; E542-K546 HydrophobicContact CG-CD 4.47Å; E542-K546 WeakPolarHBondContact O-CG 3.35Å; E542-K546 PolarHBondContact O-N 2.73Å; E542-K546 VanDerWaalsContact OE1-CE 3.27Å; E542-K546 WeakPolarHBondContact OE1-CE 3.26Å; E542-K546 IonicContact OE1-NZ 2.64Å; E542-K546 PolarHBondContact OE1-NZ 3.24Å
543K88.1Confident86.4Confident147 Ų14782.4 Ų82.464%0.63942%0.424SS*.Hα-helixtrans-63-43.4176.2-75.3175.3-176.8178.20112.3Q539 K540 I541 A547Q539-K543 WeakPolarHBondContact O-CG 3.13Å; Q539-K543 PolarHBondContact O-N 2.57Å; K540-K543 PolarHBondContact O-N 2.6Å; I541-K543 PolarHBondContact O-N 3.07Å; K543-A547 WeakPolarHBondContact O-CB 3.4Å; K543-A547 PolarHBondContact O-N 3.03Å
544L87.6Confident85.4Confident100 Ų10087.4 Ų87.452%0.52445%0.445SS..Hα-helixtrans-66.9-42.3178.3-70.5173.4000111.4K540 I541 K546 A547 E548K540-L544 WeakPolarHBondContact O-CG 3.34Å; K540-L544 PolarHBondContact O-N 3.3Å; I541-L544 PolarHBondContact O-N 2.96Å; L544-K546 PolarHBondContact O-N 3.28Å; L544-A547 WeakPolarHBondContact O-CB 3.48Å; L544-A547 PolarHBondContact O-N 3.37Å; L544-A547 VanDerWaalsContact O-N 3.16Å; L544-E548 PolarHBondContact O-N 2.81Å
545T89.1Confident84.2Confident61 Ų6186 Ų8637%0.37444%0.444SS..Hα-helixtrans-61.8-44.9177.2-51.40000111I541 E542 A547 E548 E549I541-T545 WeakPolarHBondContact O-CB 3.1Å; I541-T545 PolarHBondContact O-N 3.35Å; I541-T545 PolarHBondContact O-OG1 3.21Å; E542-T545 PolarHBondContact O-N 2.98Å; T545-A547 VanDerWaalsContact C-N 3.33Å; T545-A547 PolarHBondContact O-N 2.8Å; T545-E548 PolarHBondContact O-N 3.08Å; T545-E549 WeakPolarHBondContact O-CG 3.35Å; T545-E549 PolarHBondContact O-N 3.27Å
546K87.7Confident82.8Confident105 Ų10589.6 Ų89.646%0.45746%0.458SS..Hα-helixtrans-62.4-38.9174-73.4176.2-1751700112.5E542 L544 E549 I550E542-K546 HydrophobicContact CG-CD 4.47Å; E542-K546 WeakPolarHBondContact O-CG 3.35Å; E542-K546 PolarHBondContact O-N 2.73Å; E542-K546 VanDerWaalsContact OE1-CE 3.27Å; E542-K546 WeakPolarHBondContact OE1-CE 3.26Å; E542-K546 IonicContact OE1-NZ 2.64Å; E542-K546 PolarHBondContact OE1-NZ 3.24Å; L544-K546 PolarHBondContact O-N 3.28Å; K546-E549 PolarHBondContact O-N 2.87Å; K546-I550 WeakPolarHBondContact O-CD1 3.42Å; K546-I550 VanDerWaalsContact O-CG1 3.23Å; K546-I550 WeakPolarHBondContact O-CG1 3.3Å; K546-I550 PolarHBondContact O-N 3.03Å
547A86Confident81.1Confident53 Ų5393.4 Ų93.444%0.43849%0.486SS..Hα-helixtrans-66.5-39.5176.900000111.8K543 L544 T545 I550 S551K543-A547 WeakPolarHBondContact O-CB 3.4Å; K543-A547 PolarHBondContact O-N 3.03Å; L544-A547 WeakPolarHBondContact O-CB 3.48Å; L544-A547 PolarHBondContact O-N 3.37Å; L544-A547 VanDerWaalsContact O-N 3.16Å; T545-A547 VanDerWaalsContact C-N 3.33Å; T545-A547 PolarHBondContact O-N 2.8Å; A547-I550 PolarHBondContact O-N 2.79Å; A547-S551 VanDerWaalsContact O-CB 3.32Å; A547-S551 WeakPolarHBondContact O-CB 3.38Å; A547-S551 PolarHBondContact O-N 2.99Å
548E85.1Confident79.4Confident139 Ų13997.4 Ų97.465%0.6550%0.503SS*.Hα-helixtrans-66.1-41.9173.6-76.6-174.816800112.1L544 T545 I550 S551 S552L544-E548 PolarHBondContact O-N 2.81Å; T545-E548 PolarHBondContact O-N 3.08Å; E548-I550 PolarHBondContact O-N 3.43Å; E548-S551 PolarHBondContact O-N 2.82Å; E548-S552 WeakPolarHBondContact O-CB 3.48Å; E548-S552 PolarHBondContact O-N 3.02Å; E548-S552 PolarHBondContact O-OG 2.78Å
549E81.5Confident77.4Confident113 Ų11396.6 Ų96.653%0.52852%0.515SS..Hα-helixtrans-58.9-47.7173.7-75.8176.2178.300111.2T545 K546 S551 S552 L553T545-E549 WeakPolarHBondContact O-CG 3.35Å; T545-E549 PolarHBondContact O-N 3.27Å; K546-E549 PolarHBondContact O-N 2.87Å; E549-S551 VanDerWaalsContact C-N 3.34Å; E549-S551 PolarHBondContact O-N 3.18Å; E549-S552 PolarHBondContact O-N 2.9Å; E549-S552 PolarHBondContact O-OG 3.33Å; E549-L553 WeakPolarHBondContact O-CG 3.33Å; E549-L553 PolarHBondContact O-N 2.86Å
550I79.5Confident75.3Confident96 Ų96103 Ų10349%0.49255%0.545SS..Hα-helixtrans-61.2-42.7175.6-67.7164.7000111.1K546 A547 E548 L553 K554K546-I550 WeakPolarHBondContact O-CD1 3.42Å; K546-I550 VanDerWaalsContact O-CG1 3.23Å; K546-I550 WeakPolarHBondContact O-CG1 3.3Å; K546-I550 PolarHBondContact O-N 3.03Å; A547-I550 PolarHBondContact O-N 2.79Å; E548-I550 PolarHBondContact O-N 3.43Å; I550-L553 PolarHBondContact O-N 3.17Å; I550-K554 HydrophobicContact CG2-CD 4.48Å; I550-K554 WeakPolarHBondContact O-CG 3.31Å; I550-K554 PolarHBondContact O-N 2.71Å
551S78.8Confident73Confident74 Ų74104.4 Ų104.452%0.51756%0.561SS.*Hα-helixtrans-63.6-41.7177.4-170.20000111.6A547 E548 E549 K554 S555A547-S551 VanDerWaalsContact O-CB 3.32Å; A547-S551 WeakPolarHBondContact O-CB 3.38Å; A547-S551 PolarHBondContact O-N 2.99Å; E548-S551 PolarHBondContact O-N 2.82Å; E549-S551 VanDerWaalsContact C-N 3.34Å; E549-S551 PolarHBondContact O-N 3.18Å; S551-K554 PolarHBondContact O-N 2.93Å; S551-S555 PolarHBondContact O-N 3.35Å; S551-S555 PolarHBondContact O-OG 2.98Å
552S75.3Confident70.5Confident52 Ų52107.2 Ų107.236%0.36458%0.577SS.*Hα-helixtrans-68.9-32.2177.977.60000113.2E548 E549 S555 K556E548-S552 WeakPolarHBondContact O-CB 3.48Å; E548-S552 PolarHBondContact O-N 3.02Å; E548-S552 PolarHBondContact O-OG 2.78Å; E549-S552 PolarHBondContact O-N 2.9Å; E549-S552 PolarHBondContact O-OG 3.33Å; S552-S555 WeakPolarHBondContact CA-OG 3.22Å; S552-S555 PolarHBondContact O-OG 3.42Å; S552-K556 WeakPolarHBondContact O-CB 3.49Å; S552-K556 WeakPolarHBondContact O-CG 3.14Å; S552-K556 PolarHBondContact O-N 3.46Å; S552-K556 VanDerWaalsContact O-N 3.1Å
553L72.5Confident67.6Low120 Ų120110.9 Ų110.963%0.62859%0.594SS**Hα-helixtrans-69-39.7172.1-75.2164.2000111.1E549 I550 S557E549-L553 WeakPolarHBondContact O-CG 3.33Å; E549-L553 PolarHBondContact O-N 2.86Å; I550-L553 PolarHBondContact O-N 3.17Å; L553-S557 PolarHBondContact O-N 3.24Å; L553-S557 VanDerWaalsContact O-N 3.13Å; L553-S557 PolarHBondContact O-OG 2.96Å
554K72Confident64.8Low127 Ų127111.5 Ų111.555%0.55260%0.601SS**Hα-helixtrans-65.6-45.3175.1-74.3179.8178.4-1750112.3I550 S551 K556 S557 E558I550-K554 HydrophobicContact CG2-CD 4.48Å; I550-K554 WeakPolarHBondContact O-CG 3.31Å; I550-K554 PolarHBondContact O-N 2.71Å; S551-K554 PolarHBondContact O-N 2.93Å; K554-K556 VanDerWaalsContact C-N 3.31Å; K554-K556 PolarHBondContact O-N 2.85Å; K554-S557 WeakPolarHBondContact CA-OG 3.32Å; K554-S557 PolarHBondContact O-N 2.84Å; K554-S557 VanDerWaalsContact O-N 3.13Å; K554-S557 PolarHBondContact O-OG 3.32Å; K554-E558 WeakPolarHBondContact O-CG 3.31Å; K554-E558 PolarHBondContact O-N 3.32Å; K554-E558 VanDerWaalsContact O-N 3.1Å
555S66.2Low62.1Low68 Ų68114 Ų11448%0.47662%0.616SS.*Hα-helixtrans-67.3-31.4178.763.90000112.7S551 S552 E558 G559S551-S555 PolarHBondContact O-N 3.35Å; S551-S555 PolarHBondContact O-OG 2.98Å; S552-S555 WeakPolarHBondContact CA-OG 3.22Å; S552-S555 PolarHBondContact O-OG 3.42Å; S555-E558 PolarHBondContact O-N 3.45Å; S555-G559 PolarHBondContact O-N 2.94Å; S555-G559 VanDerWaalsContact O-N 3.1Å
556K61Low59.2Low168 Ų168114.1 Ų114.173%0.7363%0.629SS**Hα-helixtrans-68.8-31.5170.6-79.8-179.6178.9176.20113.6S552 K554 E558S552-K556 WeakPolarHBondContact O-CB 3.49Å; S552-K556 WeakPolarHBondContact O-CG 3.14Å; S552-K556 PolarHBondContact O-N 3.46Å; S552-K556 VanDerWaalsContact O-N 3.1Å; K554-K556 VanDerWaalsContact C-N 3.31Å; K554-K556 PolarHBondContact O-N 2.85Å; K556-E558 VanDerWaalsContact C-N 3.34Å
557S56.3Low56.3Low90 Ų90114.7 Ų114.763%0.62965%0.646SS**Hα-helixtrans-75.1-21.9172.952.80000113.8L553 K554L553-S557 PolarHBondContact O-N 3.24Å; L553-S557 VanDerWaalsContact O-N 3.13Å; L553-S557 PolarHBondContact O-OG 2.96Å; K554-S557 WeakPolarHBondContact CA-OG 3.32Å; K554-S557 PolarHBondContact O-N 2.84Å; K554-S557 VanDerWaalsContact O-N 3.13Å; K554-S557 PolarHBondContact O-OG 3.32Å
558E54.4Low53.6Low135 Ų135116.6 Ų116.663%0.63166%0.656SS**Hα-helixtrans-92.5-19-179.7-71.2174.1178.700113.2K554 S555 K556 E560 S561K554-E558 WeakPolarHBondContact O-CG 3.31Å; K554-E558 PolarHBondContact O-N 3.32Å; K554-E558 VanDerWaalsContact O-N 3.1Å; S555-E558 PolarHBondContact O-N 3.45Å; K556-E558 VanDerWaalsContact C-N 3.34Å; E558-E560 PolarHBondContact O-N 3.49Å; E558-E560 VanDerWaalsContact O-N 3.13Å; E558-S561 PolarHBondContact O-N 2.62Å
559G49.6Very low50.9Low68 Ų68117 Ų11770%0.70166%0.661SS**THydrogen-bonded Turntrans-69.8-0.2-178.500000116.7S555S555-G559 PolarHBondContact O-N 2.94Å; S555-G559 VanDerWaalsContact O-N 3.1Å
560E43.7Very low48.4Very low193 Ų193117.9 Ų117.990%0.90267%0.669SS**THydrogen-bonded Turntrans-96.711.4174-81.2-171.7165.500114.1E558E558-E560 PolarHBondContact O-N 3.49Å; E558-E560 VanDerWaalsContact O-N 3.13Å
561S40Very low46Very low79 Ų79118.1 Ų118.155%0.55268%0.68SS**SBendtrans-141.6126.1174.857.50000114.4E558E558-S561 PolarHBondContact O-N 2.62Å
562N36.5Very low43.6Very low159 Ų159118.4 Ų118.485%0.8569%0.686SS**  trans100.483.5154.8-57.3-24.5000117.7
563E29.9Very low41.3Very low181 Ų181123.4 Ų123.485%0.84671%0.707SS**  trans-54.1159.7139.7-68.2179.9141.300112.9
564M28.9Very low39.3Very low160 Ų160125.3 Ų125.379%0.78872%0.718SS**  trans99.2120157.4-86.7-175.7-167.100120.9
565N31.4Very low37.3Very low154 Ų154123.8 Ų123.882%0.82473%0.729SS**  trans79.8120.8149.7-57.8-20.4000116.6
566G27.3Very low35.4Very low63 Ų63124.2 Ų124.265%0.64975%0.745SS**  cis126.4120.311.900000110.1
567S27.2Very low33.9Very low117 Ų117123.7 Ų123.782%0.81875%0.75SS**  trans64.1142.5155.367.50000118
568S28.8Very low32.4Very low92 Ų92123.9 Ų123.964%0.64375%0.751SS**  cis173.5150.14.4-97.30000106.8
569I28.2Very low31.1Very low147 Ų147126.1 Ų126.175%0.75476%0.762SS**  trans70.2136.9131.2-67.8173.5000116.6
570D28.5Very low30.1Very low132 Ų132128 Ų12871%0.70676%0.764SS**  cis-173.5161.718.1-133.4-14.5000111.7
571S29Very low29.2Very low102 Ų102123.9 Ų123.971%0.71376%0.763SS**  trans53.1154.9135.875.40000121.7
572A29.9Very low28.5Very low79 Ų79125.9 Ų125.965%0.65378%0.777SS**  cis-174.3148.8-9.600000109.1
573I26.8Very low28Very low158 Ų158125.8 Ų125.881%0.8178%0.776SS**  trans50119.1138.1-54166.2000120.3
574D30.8Very low27.8Very low159 Ų159122.9 Ų122.985%0.8578%0.776SS**  -160.5153.4116.9-135-15.7000114.7
575A28.1Very low27.8Very low95 Ų95118 Ų11879%0.78577%0.767SS**  trans-97.5153.3-166.100000114.3
576G28.4Very low27.7Very low78 Ų78120.7 Ų120.780%0.80477%0.771SS**  trans-176.9101171.700000115.3
577N27.7Very low28Very low156 Ų156124.6 Ų124.683%0.83478%0.777SS**  trans22.4123.6152.2-84.71.5000123.7
578S25.4Very low28.6Very low95 Ų95124.2 Ų124.266%0.66478%0.775SS**  29.3118.613064.60000120.1
579E27.5Very low29.2Very low182 Ų182128.6 Ų128.685%0.8579%0.785SS**  -173.7134.5107.2-101.8176.5-170.500112.1
580S27.4Very low29.8Very low108 Ų108125 Ų12576%0.75577%0.771SS**  trans64.486.3142.4-49.30000118.9S582S580-S582 PolarHBondContact O-N 2.9Å
581A26.3Very low30.9Very low105 Ų105120.7 Ų120.787%0.86875%0.75SS**  trans-65.2114.516300000112.4
582S25.7Very low32.1Very low121 Ų121120.4 Ų120.485%0.84675%0.746SS**  trans-123.967.4157.751.70000108.8S580S580-S582 PolarHBondContact O-N 2.9Å
583N24.6Very low33.3Very low157 Ų157121 Ų12184%0.8474%0.741SS**  trans-102.492.4-179.7-141.46.6000109.6
584S26.5Very low34.9Very low120 Ų120114.6 Ų114.684%0.83971%0.709SS**  trans-14948.5163.372.70000111.7
585G28.8Very low36.2Very low59 Ų59112.4 Ų112.461%0.60869%0.693SS**  trans-100.386159.100000108.2D587G585-D587 PolarHBondContact O-N 2.84Å
586K28.7Very low37.5Very low209 Ų209113.1 Ų113.191%0.90968%0.683SS**  trans-72.974.7165.3-79.5-174.6177.81790107.6S588K586-S588 PolarHBondContact O-N 3.26Å; K586-S588 VanDerWaalsContact O-N 3.12Å
587D34Very low39.1Very low145 Ų145111.2 Ų111.278%0.77566%0.657SS**  trans-64.4107.7158.1-78.8-31.6000106.2G585 Q589G585-D587 PolarHBondContact O-N 2.84Å; D587-Q589 PolarHBondContact O-N 2.91Å
588S39.5Very low40.8Very low110 Ų110104 Ų10477%0.76962%0.618SS**  trans-63.486.2169.453.70000107.6K586 T590K586-S588 PolarHBondContact O-N 3.26Å; K586-S588 VanDerWaalsContact O-N 3.12Å; S588-T590 VanDerWaalsContact C-N 3.28Å; S588-T590 PolarHBondContact O-N 3.23Å
589Q41.9Very low42.6Very low183 Ų183107 Ų10786%0.85562%0.615SS**  trans-60.197.8162.8-72.6-174.6-8.900106.5D587 S591D587-Q589 PolarHBondContact O-N 2.91Å; Q589-S591 PolarHBondContact O-N 3.14Å
590T39.9Very low44.8Very low73 Ų73103 Ų10345%0.44860%0.6SS.*  trans-56.3121.2166.821.60000107.2S588 D594S588-T590 VanDerWaalsContact C-N 3.28Å; S588-T590 PolarHBondContact O-N 3.23Å; T590-D594 HydrophobicContact CG2-CB 4.26Å
591S53.1Low47.5Very low40 Ų4098.3 Ų98.328%0.2857%0.566SS.*  trans-65.9156.1179.467.90000110Q589 V593 D594 E595Q589-S591 PolarHBondContact O-N 3.14Å; S591-V593 PolarHBondContact O-N 3.46Å; S591-V593 VanDerWaalsContact O-N 3.09Å; S591-D594 WeakPolarHBondContact CB-OD2 3.46Å; S591-D594 PolarHBondContact N-OD2 3.45Å; S591-D594 WeakPolarHBondContact O-CA 3.46Å; S591-D594 WeakPolarHBondContact O-CB 3.47Å; S591-D594 PolarHBondContact O-N 2.67Å; S591-D594 PolarHBondContact OG-N 2.78Å; S591-D594 VanDerWaalsContact OG-N 3.08Å; S591-D594 PolarHBondContact OG-OD1 3.17Å; S591-D594 PolarHBondContact OG-OD2 3.3Å; S591-E595 PolarHBondContact O-N 2.98Å; S591-E595 VanDerWaalsContact O-N 3.12Å
592P53.8Low50.6Low96 Ų9693.7 Ų93.762%0.62353%0.528SS*.Hα-helixtrans-53.1-31.4170.5-26.434.4000112L596P592-L596 WeakPolarHBondContact O-CB 3.22Å; P592-L596 WeakPolarHBondContact O-CD1 3.26Å; P592-L596 VanDerWaalsContact O-CG 3.28Å; P592-L596 WeakPolarHBondContact O-CG 3.35Å; P592-L596 PolarHBondContact O-N 3.32Å
593V55.4Low53.7Low91 Ų9188.4 Ų88.455%0.55249%0.491SS*.Hα-helixtrans-65.2-39.4173.2-177.80000111.3S591 L596 T597S591-V593 PolarHBondContact O-N 3.46Å; S591-V593 VanDerWaalsContact O-N 3.09Å; V593-L596 CarbonylContact O-C 3.55Å; V593-L596 PolarHBondContact O-N 2.86Å; V593-T597 HydrophobicContact CG1-CG2 4.08Å; V593-T597 VanDerWaalsContact O-CB 3.25Å; V593-T597 WeakPolarHBondContact O-CB 3.44Å; V593-T597 WeakPolarHBondContact O-CG2 3.45Å; V593-T597 PolarHBondContact O-N 3.23Å; V593-T597 PolarHBondContact O-OG1 2.84Å
594D58.7Low56.9Low25 Ų2586.2 Ų86.213%0.13448%0.478CS..Hα-helixtrans-68.2-39.3178.4-59.1-43.5000111.7T590 S591 T597 G598 R599T590-D594 HydrophobicContact CG2-CB 4.26Å; S591-D594 WeakPolarHBondContact CB-OD2 3.46Å; S591-D594 PolarHBondContact N-OD2 3.45Å; S591-D594 WeakPolarHBondContact O-CA 3.46Å; S591-D594 WeakPolarHBondContact O-CB 3.47Å; S591-D594 PolarHBondContact O-N 2.67Å; S591-D594 PolarHBondContact OG-N 2.78Å; S591-D594 VanDerWaalsContact OG-N 3.08Å; S591-D594 PolarHBondContact OG-OD1 3.17Å; S591-D594 PolarHBondContact OG-OD2 3.3Å; D594-T597 WeakPolarHBondContact CA-OG1 3.5Å; D594-T597 PolarHBondContact O-N 2.84Å; D594-T597 PolarHBondContact O-OG1 3.24Å; D594-G598 PolarHBondContact O-N 3.47Å; D594-R599 HydrophobicContact CB-CB 4Å; D594-R599 PolarHBondContact O-N 3.25Å; D594-R599 WeakPolarHBondContact OD1-CD 3.36Å; D594-R599 IonicContact OD1-CZ 3.76Å; D594-R599 IonicContact OD1-NE 3.33Å; D594-R599 IonicContact OD1-NH1 3.88Å; D594-R599 PolarHBondContact OD1-NH1 2.81Å
595E59.8Low59.8Low112 Ų11291 Ų9152%0.52348%0.478SS..Hα-helixtrans-66.5-46.4171.3-72.4-178.7172.800111.6S591 T597 G598S591-E595 PolarHBondContact O-N 2.98Å; S591-E595 VanDerWaalsContact O-N 3.12Å; E595-T597 PolarHBondContact O-N 2.85Å; E595-G598 PolarHBondContact O-N 2.86Å
596L55.2Low62.9Low110 Ų11089.3 Ų89.358%0.57645%0.453SS*.Hα-helixtrans-66.5-19176.6-83.1159.2000113.4K540 P592 V593K540-L596 WeakPolarHBondContact CD-O 3.28Å; K540-L596 WeakPolarHBondContact CE-O 3.49Å; K540-L596 PolarHBondContact NZ-O 3.48Å; P592-L596 WeakPolarHBondContact O-CB 3.22Å; P592-L596 WeakPolarHBondContact O-CD1 3.26Å; P592-L596 VanDerWaalsContact O-CG 3.28Å; P592-L596 WeakPolarHBondContact O-CG 3.35Å; P592-L596 PolarHBondContact O-N 3.32Å; V593-L596 CarbonylContact O-C 3.55Å; V593-L596 PolarHBondContact O-N 2.86Å
597T60.2Low65.9Low39 Ų3981.7 Ų81.724%0.23942%0.424CS..Hα-helixtrans-104.9-5176.855.50000112.5F536 V593 D594 E595 R599F536-T597 WeakPolarHBondContact CE1-O 3.39Å; V593-T597 HydrophobicContact CG1-CG2 4.08Å; V593-T597 VanDerWaalsContact O-CB 3.25Å; V593-T597 WeakPolarHBondContact O-CB 3.44Å; V593-T597 WeakPolarHBondContact O-CG2 3.45Å; V593-T597 PolarHBondContact O-N 3.23Å; V593-T597 PolarHBondContact O-OG1 2.84Å; D594-T597 WeakPolarHBondContact CA-OG1 3.5Å; D594-T597 PolarHBondContact O-N 2.84Å; D594-T597 PolarHBondContact O-OG1 3.24Å; E595-T597 PolarHBondContact O-N 2.85Å; T597-R599 PolarHBondContact O-N 2.88Å
598G63.5Low68.6Low3 Ų378 Ų783%0.03141%0.407CS..THydrogen-bonded Turntrans60.427.7-172.600000112.6D594 E595 T601D594-G598 PolarHBondContact O-N 3.47Å; E595-G598 PolarHBondContact O-N 2.86Å; G598-T601 WeakPolarHBondContact O-CB 3.49Å; G598-T601 WeakPolarHBondContact O-CG2 3.49Å; G598-T601 PolarHBondContact O-N 3.01Å; G598-T601 VanDerWaalsContact O-N 3.14Å; G598-T601 PolarHBondContact O-OG1 3.3Å
599R64.3Low70.8Confident158 Ų15873.2 Ų73.260%0.59637%0.373SS*.THydrogen-bonded Turntrans-57.9143.2179.3-152.6179.6-174.5176.5-0.6109.3D594 T597 T601D594-R599 HydrophobicContact CB-CB 4Å; D594-R599 PolarHBondContact O-N 3.25Å; D594-R599 WeakPolarHBondContact OD1-CD 3.36Å; D594-R599 IonicContact OD1-CZ 3.76Å; D594-R599 IonicContact OD1-NE 3.33Å; D594-R599 IonicContact OD1-NH1 3.88Å; D594-R599 PolarHBondContact OD1-NH1 2.81Å; T597-R599 PolarHBondContact O-N 2.88Å; R599-T601 PolarHBondContact O-N 3.23Å
600D73.6Confident72.7Confident100 Ų10067.3 Ų67.354%0.53535%0.352SS..THydrogen-bonded Turntrans63.915.7-174.1-51.1-30.3000116.2K671D600-K671 PolarHBondContact O-NZ 2.96Å
601T84.2Confident74.9Confident8 Ų870.7 Ų70.75%0.04936%0.362CS..SBendtrans-100.1-18.1167.371.50000113G598 R599 C635 L651 P652 G653G598-T601 WeakPolarHBondContact O-CB 3.49Å; G598-T601 WeakPolarHBondContact O-CG2 3.49Å; G598-T601 PolarHBondContact O-N 3.01Å; G598-T601 VanDerWaalsContact O-N 3.14Å; G598-T601 PolarHBondContact O-OG1 3.3Å; R599-T601 PolarHBondContact O-N 3.23Å; T601-C635 WeakPolarHBondContact O-CA 3.46Å; T601-C635 PolarHBondContact O-SG 3.33Å; T601-L651 WeakPolarHBondContact O-CD1 3.16Å; T601-P652 HydrophobicContact CG2-CB 4.11Å; T601-P652 HydrophobicContact CG2-CG 3.99Å; T601-G653 PolarHBondContact OG1-N 2.87Å
602V90.4Very high76.5Confident9 Ų969.2 Ų69.26%0.05535%0.353CS..SBendtrans-126.4129.1178.8179.70000109H533 I604 L651 H654H533-V602 HydrophobicContact CB-CG1 4.22Å; V602-I604 PolarHBondContact O-N 3.22Å; V602-L651 HydrophobicContact CG2-CB 4.06Å; V602-L651 HydrophobicContact CG2-CD1 4Å; V602-H654 WeakPolarHBondContact CG1-NE2 3.31Å
603A92.4Very high78.1Confident9 Ų968.7 Ų68.77%0.07435%0.352CS..  trans-80.7113178.700000111.5W606 W634 C635 C636A603-W606 PolarHBondContact O-NE1 3.3Å; A603-W606 VanDerWaalsContact O-NE1 3.16Å; A603-W634 PolarHBondContact N-O 2.78Å; A603-C635 PolarHBondContact N-O 3.1Å; A603-C636 VanDerWaalsContact CB-C 3.46Å
604I90.1Very high79.9Confident111 Ų11170 Ų7057%0.56935%0.346SS*.SBendtrans-70.7-37.9174.8-60.3174.6000111.1Q526 L530 V602Q526-I604 PolarHBondContact NE2-O 3.35Å; L530-I604 HydrophobicContact CD2-CG2 4.35Å; V602-I604 PolarHBondContact O-N 3.22Å
605R89.1Confident81.5Confident220 Ų22068.9 Ų68.983%0.8334%0.341SS*.SBendtrans-112.9130.9178.2-66.4-174.4-179.9-178.50.3110.1
606W93.4Very high83.3Confident24 Ų2466 Ų669%0.09133%0.333CS..  trans-107.4144.7175.5-71.424.1000109.5Q525 Q526 A603 H632 W634 G637Q525-W606 HydrophobicContact CB-CH2 3.68Å; Q525-W606 HydrophobicContact CB-CZ3 3.82Å; Q526-W606 HydrophobicContact CB-CD2 3.96Å; Q526-W606 HydrophobicContact CB-CE3 4.04Å; Q526-W606 HydrophobicContact CB-CG 4.42Å; Q526-W606 HydrophobicContact CB-CZ2 4.46Å; Q526-W606 HydrophobicContact CB-CZ3 4.34Å; Q526-W606 HydrophobicContact CG-CD2 4.02Å; Q526-W606 HydrophobicContact CG-CG 4.01Å; A603-W606 PolarHBondContact O-NE1 3.3Å; A603-W606 VanDerWaalsContact O-NE1 3.16Å; W606-H632 HydrophobicContact CD2-CB 4.09Å; W606-H632 HydrophobicContact CE3-CB 3.49Å; W606-H632 VanDerWaalsContact CE3-CB 3.49Å; W606-H632 AromaticContact CE3-CD2 3.53Å; W606-H632 AromaticContact CE3-CE1 3.77Å; W606-H632 AromaticContact CE3-CG 3.23Å; W606-H632 AromaticContact CE3-ND1 3.46Å; W606-H632 AromaticContact CE3-NE2 3.86Å; W606-H632 HydrophobicContact CH2-CB 3.95Å; W606-H632 HydrophobicContact CZ3-CB 3.4Å; W606-H632 VanDerWaalsContact CZ3-CB 3.4Å; W606-H632 AromaticContact CZ3-CG 3.54Å; W606-H632 AromaticContact CZ3-ND1 3.6Å; W606-W634 AromaticContact CH2-CD1 3.57Å; W606-W634 HydrophobicContact CH2-CD2 4.08Å; W606-W634 AromaticContact CH2-CE2 3.79Å; W606-W634 AromaticContact CH2-CG 3.98Å; W606-W634 HydrophobicContact CH2-CG 3.98Å; W606-W634 HydrophobicContact CH2-CZ2 4.47Å; W606-W634 AromaticContact CH2-NE1 3.43Å; W606-W634 HydrophobicContact CZ2-CB 4.27Å; W606-W634 AromaticContact CZ2-CD1 3.8Å; W606-W634 HydrophobicContact CZ2-CD2 4.04Å; W606-W634 AromaticContact CZ2-CG 3.79Å; W606-W634 HydrophobicContact CZ2-CG 3.79Å; W606-G637 WeakPolarHBondContact CA-O 3.41Å
607T92.4Very high85.1Confident50 Ų5062.1 Ų62.131%0.30731%0.313SS..  trans-62.6137170.3-58.30000109.3V609 H632 G637 V639T607-V609 PolarHBondContact O-N 2.71Å; T607-H632 PolarHBondContact O-NE2 2.62Å; T607-G637 PolarHBondContact N-O 3.26Å; T607-V639 HydrophobicContact CG2-CG2 4.35Å
608V88.9Confident86.6Confident67 Ų6764.8 Ų64.841%0.40634%0.339SS..  trans-64.9126.5176.7-173.40000108.9S610 E611 A612V608-S610 VanDerWaalsContact C-N 3.26Å; V608-S610 WeakPolarHBondContact CG1-OG 3.48Å; V608-S610 PolarHBondContact O-N 2.8Å; V608-E611 HydrophobicContact CB-CB 4.25Å; V608-E611 HydrophobicContact CB-CG 3.9Å; V608-E611 HydrophobicContact CG1-CG 4.26Å; V608-E611 PolarHBondContact O-N 3.35Å; V608-E611 VanDerWaalsContact O-N 3.09Å; V608-A612 PolarHBondContact O-N 3.32Å
609V86.1Confident87.8Confident9 Ų973 Ų736%0.05538%0.376CS..THydrogen-bonded Turntrans-56.3-41.1-174.9178.30000112.1A522 T607 E611 A612 K630 H632A522-V609 HydrophobicContact CB-CG2 3.59Å; T607-V609 PolarHBondContact O-N 2.71Å; V609-E611 VanDerWaalsContact C-N 3.29Å; V609-E611 PolarHBondContact O-N 3.16Å; V609-A612 PolarHBondContact O-N 3.5Å; V609-K630 HydrophobicContact CG1-CB 4.31Å; V609-K630 HydrophobicContact CG1-CD 3.86Å; V609-K630 HydrophobicContact CG1-CG 4.28Å; V609-K630 WeakPolarHBondContact O-CD 3.37Å; V609-K630 PolarHBondContact O-NZ 3.48Å; V609-H632 WeakPolarHBondContact CG2-CE1 3.45Å
610S81.6Confident89Confident60 Ų6067.8 Ų67.842%0.4236%0.364SS..THydrogen-bonded Turntrans-68.4-27.5-178.551.70000113.1D514 V608D514-S610 WeakPolarHBondContact OD2-CA 3.2Å; D514-S610 WeakPolarHBondContact OD2-CB 3.36Å; V608-S610 VanDerWaalsContact C-N 3.26Å; V608-S610 WeakPolarHBondContact CG1-OG 3.48Å; V608-S610 PolarHBondContact O-N 2.8Å
611E85.8Confident89.8Confident143 Ų14366.8 Ų66.867%0.66836%0.358SS*.THydrogen-bonded Turntrans-79.7-20.3177.4-63.3176.1178.300112.4V608 V609 S613V608-E611 HydrophobicContact CB-CB 4.25Å; V608-E611 HydrophobicContact CB-CG 3.9Å; V608-E611 HydrophobicContact CG1-CG 4.26Å; V608-E611 PolarHBondContact O-N 3.35Å; V608-E611 VanDerWaalsContact O-N 3.09Å; V609-E611 VanDerWaalsContact C-N 3.29Å; V609-E611 PolarHBondContact O-N 3.16Å; E611-S613 PolarHBondContact O-N 3.12Å
612A88.7Confident89.8Confident9 Ų968.5 Ų68.57%0.07437%0.373CS..  trans-78.1104.3178.500000111.3V608 V609 F624 K630 V639V608-A612 PolarHBondContact O-N 3.32Å; V609-A612 PolarHBondContact O-N 3.5Å; A612-F624 HydrophobicContact CB-CE2 4.28Å; A612-F624 WeakPolarHBondContact O-CD2 3.19Å; A612-K630 HydrophobicContact CB-CD 4.32Å; A612-K630 WeakPolarHBondContact O-CE 3.24Å; A612-K630 PolarHBondContact O-NZ 2.78Å; A612-V639 HydrophobicContact CB-CB 3.68Å; A612-V639 HydrophobicContact CB-CG1 3.69Å; A612-V639 HydrophobicContact CB-CG2 3.92Å
613S87Confident89.5Confident86 Ų8669.4 Ų69.460%0.60138%0.382SS*.  trans-92.6-17.4176.359.80000113.9E611 A623 F624E611-S613 PolarHBondContact O-N 3.12Å; S613-A623 WeakPolarHBondContact O-CA 3.24Å; S613-F624 PolarHBondContact O-N 2.79Å
614R91.9Very high89Confident117 Ų11770.1 Ų70.144%0.44238%0.383SS..BIsolated β-bridgetrans-142.1156-177.2-49.7-175.173.694.3-2.3112.4S616 N621 A622 A623 F624R614-S616 PolarHBondContact O-N 2.82Å; R614-N621 WeakPolarHBondContact CD-OD1 3.39Å; R614-N621 PolarHBondContact NE-O 2.84Å; R614-N621 PolarHBondContact NE-OD1 2.93Å; R614-N621 PolarHBondContact NH2-O 2.8Å; R614-A622 CarbonylContact C-O 3.59Å; R614-A622 VanDerWaalsContact CA-O 3.24Å; R614-A622 WeakPolarHBondContact CA-O 3.31Å; R614-A623 HydrophobicContact CG-CB 4.49Å; R614-F624 WeakPolarHBondContact O-CE2 3.42Å
615C93.6Very high88.1Confident2 Ų268.9 Ų68.91%0.01437%0.372CS..  trans-61.9128.9173.1-1790000111.1N617 A622 F624 C641C615-N617 PolarHBondContact O-N 2.87Å; C615-A622 PolarHBondContact N-O 3.39Å; C615-F624 HydrophobicContact CB-CE1 4.46Å; C615-F624 HydrophobicContact CB-CZ 4.21Å; C615-C641 HydrophobicContact CB-CB 4.46Å
616S96.1Very high87.1Confident51 Ų5160.9 Ų60.936%0.35735%0.348SS..SBendtrans-72.9-4.7-177.9-56.30000114.4R614 A618 V639R614-S616 PolarHBondContact O-N 2.82Å; S616-A618 PolarHBondContact O-N 2.9Å; S616-V639 WeakPolarHBondContact CB-O 3.48Å; S616-V639 PolarHBondContact N-O 3.38Å; S616-V639 PolarHBondContact OG-N 2.84Å; S616-V639 PolarHBondContact OG-O 2.87Å
617N94Very high85.8Confident30 Ų3061 Ų6116%0.1636%0.356CS..  trans-76113.6171.1178.5-10.3000108.9C615 Q619 C620 N621 F640 C644C615-N617 PolarHBondContact O-N 2.87Å; N617-Q619 PolarHBondContact O-N 3.09Å; N617-Q619 VanDerWaalsContact O-N 3.14Å; N617-Q619 PolarHBondContact OD1-N 3.47Å; N617-C620 HydrophobicContact CB-CB 4.02Å; N617-C620 CarbonylContact O-C 3.57Å; N617-C620 PolarHBondContact O-N 2.47Å; N617-N621 PolarHBondContact O-N 3.39Å; N617-F640 HydrophobicContact CB-CD1 4.06Å; N617-F640 HydrophobicContact CB-CE1 4.11Å; N617-C644 HydrophobicContact CB-CB 4.16Å; N617-C644 PolarHBondContact ND2-SG 2.97Å; N617-C644 VanDerWaalsContact ND2-SG 3.41Å
618A90.9Very high85.1Confident95 Ų9560.8 Ų60.879%0.78535%0.352SS*.THydrogen-bonded Turntrans-55.6-31.4-17800000114.4S616S616-A618 PolarHBondContact O-N 2.9Å
619Q90.4Very high84.9Confident175 Ų17558.8 Ų58.882%0.81834%0.337SS*.THydrogen-bonded Turntrans-77-26.5177.3-67179.5-15.800112.9N617N617-Q619 PolarHBondContact O-N 3.09Å; N617-Q619 VanDerWaalsContact O-N 3.14Å; N617-Q619 PolarHBondContact OD1-N 3.47Å
620C89Confident85.1Confident49 Ų4959.1 Ų59.133%0.33134%0.338SS..THydrogen-bonded Turntrans-88.4-59.6176.51760000109.9N617 A622N617-C620 HydrophobicContact CB-CB 4.02Å; N617-C620 CarbonylContact O-C 3.57Å; N617-C620 PolarHBondContact O-N 2.47Å; C620-A622 PolarHBondContact O-N 2.84Å
621N90Very high85.5Confident79 Ų7957.5 Ų57.542%0.42232%0.323SS..  trans43.226.4-177.8-167.222.5000113.3R614 N617R614-N621 WeakPolarHBondContact CD-OD1 3.39Å; R614-N621 PolarHBondContact NE-O 2.84Å; R614-N621 PolarHBondContact NE-OD1 2.93Å; R614-N621 PolarHBondContact NH2-O 2.8Å; N617-N621 PolarHBondContact O-N 3.39Å
622A84.6Confident85.9Confident44 Ų4451 Ų5136%0.36429%0.293SS..PPolyproline II helixtrans-69.9139-17600000109.6R614 C615 C620R614-A622 CarbonylContact C-O 3.59Å; R614-A622 VanDerWaalsContact CA-O 3.24Å; R614-A622 WeakPolarHBondContact CA-O 3.31Å; C615-A622 PolarHBondContact N-O 3.39Å; C620-A622 PolarHBondContact O-N 2.84Å
623A84Confident86.2Confident28 Ų2850.5 Ų50.523%0.23129%0.289CS..BIsolated β-bridgetrans-68.3136.2171.300000109.8S613 R614S613-A623 WeakPolarHBondContact O-CA 3.24Å; R614-A623 HydrophobicContact CG-CB 4.49Å
624F82Confident86.6Confident23 Ų2346.6 Ų46.610%0.10126%0.261CS..PPolyproline II helixtrans-70.7139.6174.5-66.9-61.6000110.5A612 S613 R614 C615 E628 K630 V639 C641A612-F624 HydrophobicContact CB-CE2 4.28Å; A612-F624 WeakPolarHBondContact O-CD2 3.19Å; S613-F624 PolarHBondContact O-N 2.79Å; R614-F624 WeakPolarHBondContact O-CE2 3.42Å; C615-F624 HydrophobicContact CB-CE1 4.46Å; C615-F624 HydrophobicContact CB-CZ 4.21Å; F624-E628 WeakPolarHBondContact CA-OE2 3.43Å; F624-K630 HydrophobicContact CD1-CG 4.19Å; F624-K630 HydrophobicContact CD2-CD 3.72Å; F624-K630 HydrophobicContact CD2-CG 4.14Å; F624-K630 HydrophobicContact CE1-CB 4.43Å; F624-K630 HydrophobicContact CE1-CG 4.33Å; F624-K630 HydrophobicContact CE2-CD 3.98Å; F624-K630 HydrophobicContact CE2-CG 4.28Å; F624-K630 HydrophobicContact CG-CD 4.07Å; F624-K630 HydrophobicContact CG-CG 4.09Å; F624-K630 HydrophobicContact CZ-CB 4.32Å; F624-K630 HydrophobicContact CZ-CG 4.39Å; F624-V639 HydrophobicContact CE2-CG1 3.79Å; F624-V639 HydrophobicContact CZ-CG1 3.8Å; F624-C641 HydrophobicContact CE1-CB 3.95Å
625W71.2Confident86.7Confident86 Ų8641.5 Ų41.533%0.32624%0.243SC..PPolyproline II helixtrans-69.8145.5166.9-63.395.3000109.5W16 R26 K45 G627 E628W16-W625 HydrophobicContact CH2-CZ3 4.41Å; W16-W625 HydrophobicContact CZ3-CH2 4.35Å; R26-W625 VanDerWaalsContact NH1-CH2 3.34Å; K45-W625 HydrophobicContact CB-CZ2 4.43Å; K45-W625 HydrophobicContact CD-CH2 4.28Å; K45-W625 HydrophobicContact CD-CZ2 4.49Å; W625-G627 PolarHBondContact O-N 2.9Å; W625-E628 HydrophobicContact CB-CB 4.18Å; W625-E628 PolarHBondContact N-OE2 2.65Å; W625-E628 WeakPolarHBondContact O-CB 3.45Å; W625-E628 PolarHBondContact O-N 3.45Å
626P67.2Low86.7Confident52 Ų5243.7 Ų43.734%0.33826%0.258SS..THydrogen-bonded Turntrans-49.6135.4170.9-2836.8000109.6I509 R512 E628I509-P626 HydrophobicContact CG2-CG 4.27Å; R512-P626 HydrophobicContact CB-CB 3.88Å; R512-P626 WeakPolarHBondContact CD-O 3.28Å; R512-P626 HydrophobicContact CG-CB 4.28Å; R512-P626 PolarHBondContact NE-O 3.33Å; R512-P626 PolarHBondContact NH1-O 3.1Å; P626-E628 PolarHBondContact O-N 2.93Å; P626-E628 VanDerWaalsContact O-N 3.1Å
627G67.3Low86.7Confident25 Ų2541.3 Ų41.326%0.25824%0.242SC..THydrogen-bonded Turntrans67.7-0.8-178.600000117W625 Y629W625-G627 PolarHBondContact O-N 2.9Å; G627-Y629 PolarHBondContact O-N 3.39Å
628E77.8Confident86.8Confident46 Ų4643.4 Ų43.422%0.21525%0.253CS..PPolyproline II helixtrans-58.2134.8167.8-172.3178.3160.700109.5F624 W625 P626 K630F624-E628 WeakPolarHBondContact CA-OE2 3.43Å; W625-E628 HydrophobicContact CB-CB 4.18Å; W625-E628 PolarHBondContact N-OE2 2.65Å; W625-E628 WeakPolarHBondContact O-CB 3.45Å; W625-E628 PolarHBondContact O-N 3.45Å; P626-E628 PolarHBondContact O-N 2.93Å; P626-E628 VanDerWaalsContact O-N 3.1Å; E628-K630 PolarHBondContact O-N 2.9Å
629Y84.8Confident87Confident25 Ų2538.9 Ų38.910%0.09822%0.215CC..PPolyproline II helixtrans-71.8120.8174.1-178-111.8000109.1E473 N518 I521 Q525 G627 H631E473-Y629 HydrophobicContact CB-CD1 3.8Å; E473-Y629 HydrophobicContact CB-CE1 3.54Å; E473-Y629 HydrophobicContact CB-CG 4.42Å; N518-Y629 WeakPolarHBondContact OD1-CD2 3.35Å; I521-Y629 HydrophobicContact CD1-CE2 4.49Å; I521-Y629 HydrophobicContact CG2-CE2 4.13Å; I521-Y629 WeakPolarHBondContact CG2-OH 3.33Å; Q525-Y629 PolarHBondContact NE2-OH 2.99Å; G627-Y629 PolarHBondContact O-N 3.39Å; Y629-H631 AromaticContact CD1-CD2 3.92Å; Y629-H631 AromaticContact CD1-CE1 3.46Å; Y629-H631 VanDerWaalsContact CD1-CE1 3.46Å; Y629-H631 WeakPolarHBondContact CD1-CE1 3.42Å; Y629-H631 AromaticContact CD1-ND1 3.91Å; Y629-H631 AromaticContact CD1-NE2 3.49Å; Y629-H631 WeakPolarHBondContact CD1-NE2 3.37Å; Y629-H631 AromaticContact CE1-CE1 3.5Å; Y629-H631 VanDerWaalsContact CE1-CE1 3.5Å; Y629-H631 WeakPolarHBondContact CE1-CE1 3.23Å; Y629-H631 AromaticContact CE1-ND1 3.56Å; Y629-H631 AromaticContact CE1-NE2 3.96Å
630K88.8Confident87.2Confident16 Ų1631 Ų317%0.0718%0.179CC..PPolyproline II helixtrans-98.3134.4-179.4-40.9178.2-171.8160.70108.7D514 V609 A612 F624 E628 V639D514-K630 IonicContact OD1-NZ 3.49Å; V609-K630 HydrophobicContact CG1-CB 4.31Å; V609-K630 HydrophobicContact CG1-CD 3.86Å; V609-K630 HydrophobicContact CG1-CG 4.28Å; V609-K630 WeakPolarHBondContact O-CD 3.37Å; V609-K630 PolarHBondContact O-NZ 3.48Å; A612-K630 HydrophobicContact CB-CD 4.32Å; A612-K630 WeakPolarHBondContact O-CE 3.24Å; A612-K630 PolarHBondContact O-NZ 2.78Å; F624-K630 HydrophobicContact CD1-CG 4.19Å; F624-K630 HydrophobicContact CD2-CD 3.72Å; F624-K630 HydrophobicContact CD2-CG 4.14Å; F624-K630 HydrophobicContact CE1-CB 4.43Å; F624-K630 HydrophobicContact CE1-CG 4.33Å; F624-K630 HydrophobicContact CE2-CD 3.98Å; F624-K630 HydrophobicContact CE2-CG 4.28Å; F624-K630 HydrophobicContact CG-CD 4.07Å; F624-K630 HydrophobicContact CG-CG 4.09Å; F624-K630 HydrophobicContact CZ-CB 4.32Å; F624-K630 HydrophobicContact CZ-CG 4.39Å; E628-K630 PolarHBondContact O-N 2.9Å; K630-V639 HydrophobicContact CB-CG1 3.34Å; K630-V639 HydrophobicContact CD-CG1 4.07Å; K630-V639 HydrophobicContact CG-CG1 4.25Å
631H91.4Very high87.2Confident26 Ų2629.3 Ų29.312%0.1217%0.167CC..EExtended strand (participates in β ladder)trans-102.9127.9-174-63.3-102.9000110.8E473 Y629 V639 F640 S642 A645E473-H631 IonicContact OE2-CE1 2.95Å; E473-H631 IonicContact OE2-NE2 3.14Å; Y629-H631 AromaticContact CD1-CD2 3.92Å; Y629-H631 AromaticContact CD1-CE1 3.46Å; Y629-H631 VanDerWaalsContact CD1-CE1 3.46Å; Y629-H631 WeakPolarHBondContact CD1-CE1 3.42Å; Y629-H631 AromaticContact CD1-ND1 3.91Å; Y629-H631 AromaticContact CD1-NE2 3.49Å; Y629-H631 WeakPolarHBondContact CD1-NE2 3.37Å; Y629-H631 AromaticContact CE1-CE1 3.5Å; Y629-H631 VanDerWaalsContact CE1-CE1 3.5Å; Y629-H631 WeakPolarHBondContact CE1-CE1 3.23Å; Y629-H631 AromaticContact CE1-ND1 3.56Å; Y629-H631 AromaticContact CE1-NE2 3.96Å; H631-V639 CarbonylContact O-C 3.53Å; H631-V639 WeakPolarHBondContact O-CA 3.06Å; H631-F640 PolarHBondContact N-O 2.95Å; H631-F640 PolarHBondContact O-N 3.32Å; H631-S642 PolarHBondContact CD2-N 2.84Å; H631-S642 WeakPolarHBondContact NE2-CA 3.5Å; H631-S642 WeakPolarHBondContact NE2-CB 3.5Å; H631-A645 HydrophobicContact CB-CB 3.58Å
632H94.2Very high86.9Confident6 Ų628.2 Ų28.23%0.02817%0.166CC..EExtended strand (participates in β ladder)trans-81.3139.6168.1-68.196000111.6W606 T607 V609 G637 L638 V639W606-H632 HydrophobicContact CD2-CB 4.09Å; W606-H632 HydrophobicContact CE3-CB 3.49Å; W606-H632 VanDerWaalsContact CE3-CB 3.49Å; W606-H632 AromaticContact CE3-CD2 3.53Å; W606-H632 AromaticContact CE3-CE1 3.77Å; W606-H632 AromaticContact CE3-CG 3.23Å; W606-H632 AromaticContact CE3-ND1 3.46Å; W606-H632 AromaticContact CE3-NE2 3.86Å; W606-H632 HydrophobicContact CH2-CB 3.95Å; W606-H632 HydrophobicContact CZ3-CB 3.4Å; W606-H632 VanDerWaalsContact CZ3-CB 3.4Å; W606-H632 AromaticContact CZ3-CG 3.54Å; W606-H632 AromaticContact CZ3-ND1 3.6Å; T607-H632 PolarHBondContact O-NE2 2.62Å; V609-H632 WeakPolarHBondContact CG2-CE1 3.45Å; H632-G637 PolarHBondContact CD2-O 3.15Å; H632-L638 WeakPolarHBondContact CA-O 3.43Å; H632-V639 WeakPolarHBondContact NE2-CG2 3.3Å
633C94.9Very high87Confident0 Ų031.7 Ų31.70%018%0.178CC..PPolyproline II helixtrans-80119.9160.1173.70000109C635 C636 G637 L638 F640 C665 C668C633-C635 PolarHBondContact O-N 3Å; C633-C635 VanDerWaalsContact O-N 3.16Å; C633-C635 PolarHBondContact SG-N 2.95Å; C633-C636 VanDerWaalsContact CB-SG 3.58Å; C633-C636 PolarHBondContact O-N 2.7Å; C633-C636 VanDerWaalsContact SG-SG 3.66Å; C633-G637 WeakPolarHBondContact O-CA 3.38Å; C633-G637 PolarHBondContact O-N 3.49Å; C633-L638 PolarHBondContact N-O 3.05Å; C633-F640 HydrophobicContact CB-CD2 4.03Å; C633-F640 HydrophobicContact CB-CE2 3.63Å; C633-C665 HydrophobicContact CB-CB 4Å; C633-C665 PolarHBondContact SG-N 3.45Å; C633-C668 VanDerWaalsContact SG-SG 3.67Å
634W94.1Very high87.3Confident4 Ų431 Ų312%0.01517%0.171CC..THydrogen-bonded Turntrans-68.9-16.3-178.2-70.538.5000112.9Q525 D528 A603 W606 L651 H654 V662 P663Q525-W634 HydrophobicContact CB-CH2 4.38Å; Q525-W634 HydrophobicContact CB-CZ2 3.66Å; Q525-W634 HydrophobicContact CG-CZ2 3.87Å; D528-W634 HydrophobicContact CB-CH2 4.32Å; A603-W634 PolarHBondContact N-O 2.78Å; W606-W634 AromaticContact CH2-CD1 3.57Å; W606-W634 HydrophobicContact CH2-CD2 4.08Å; W606-W634 AromaticContact CH2-CE2 3.79Å; W606-W634 AromaticContact CH2-CG 3.98Å; W606-W634 HydrophobicContact CH2-CG 3.98Å; W606-W634 HydrophobicContact CH2-CZ2 4.47Å; W606-W634 AromaticContact CH2-NE1 3.43Å; W606-W634 HydrophobicContact CZ2-CB 4.27Å; W606-W634 AromaticContact CZ2-CD1 3.8Å; W606-W634 HydrophobicContact CZ2-CD2 4.04Å; W606-W634 AromaticContact CZ2-CG 3.79Å; W606-W634 HydrophobicContact CZ2-CG 3.79Å; W634-L651 HydrophobicContact CB-CD1 3.79Å; W634-H654 AromaticContact CE3-CE1 3.91Å; W634-V662 HydrophobicContact CB-CB 4.32Å; W634-V662 HydrophobicContact CB-CG2 3.82Å; W634-V662 HydrophobicContact CD2-CB 3.64Å; W634-V662 HydrophobicContact CD2-CG1 3.93Å; W634-V662 HydrophobicContact CD2-CG2 4Å; W634-V662 HydrophobicContact CE3-CB 3.64Å; W634-V662 HydrophobicContact CE3-CG1 3.46Å; W634-V662 VanDerWaalsContact CE3-CG1 3.46Å; W634-V662 HydrophobicContact CE3-CG2 3.88Å; W634-V662 HydrophobicContact CG-CB 3.96Å; W634-V662 HydrophobicContact CG-CG2 4.02Å; W634-V662 HydrophobicContact CH2-CG1 4.05Å; W634-V662 HydrophobicContact CZ2-CG1 4.43Å; W634-V662 HydrophobicContact CZ3-CB 4.21Å; W634-V662 HydrophobicContact CZ3-CG1 3.54Å; W634-P663 PolarHBondContact N-O 2.92Å
635C94.3Very high87.5Confident9 Ų930.2 Ų30.26%0.06117%0.169CC..THydrogen-bonded Turntrans-83.2-42177.8-173.30000113.2T601 A603 C633 L651 V664 C668T601-C635 WeakPolarHBondContact O-CA 3.46Å; T601-C635 PolarHBondContact O-SG 3.33Å; A603-C635 PolarHBondContact N-O 3.1Å; C633-C635 PolarHBondContact O-N 3Å; C633-C635 VanDerWaalsContact O-N 3.16Å; C633-C635 PolarHBondContact SG-N 2.95Å; C635-L651 HydrophobicContact CB-CD2 3.98Å; C635-V664 HydrophobicContact CB-CG1 4.1Å; C635-C668 HydrophobicContact CB-CB 3.72Å
636C94.8Very high88.1Confident49 Ų4929.4 Ų29.433%0.33118%0.176SC..THydrogen-bonded Turntrans-113.9-9-178.2700000115.7A603 C633 L638A603-C636 VanDerWaalsContact CB-C 3.46Å; C633-C636 VanDerWaalsContact CB-SG 3.58Å; C633-C636 PolarHBondContact O-N 2.7Å; C633-C636 VanDerWaalsContact SG-SG 3.66Å; C636-L638 PolarHBondContact O-N 2.94Å
637G94.6Very high89.1Confident1 Ų130.9 Ų30.91%0.0118%0.175CC..  trans75.50.2177.200000114.8W606 T607 H632 C633W606-G637 WeakPolarHBondContact CA-O 3.41Å; T607-G637 PolarHBondContact N-O 3.26Å; H632-G637 PolarHBondContact CD2-O 3.15Å; C633-G637 WeakPolarHBondContact O-CA 3.38Å; C633-G637 PolarHBondContact O-N 3.49Å
638L95.9Very high90.2Very high74 Ų7435 Ų3539%0.38719%0.186SC..  trans-81.4160178.4-60.4177.9000111.9H632 C633 C636 F640H632-L638 WeakPolarHBondContact CA-O 3.43Å; C633-L638 PolarHBondContact N-O 3.05Å; C636-L638 PolarHBondContact O-N 2.94Å; L638-F640 HydrophobicContact CB-CE2 3.63Å; L638-F640 HydrophobicContact CB-CZ 3.93Å; L638-F640 VanDerWaalsContact O-CD2 3.29Å; L638-F640 WeakPolarHBondContact O-CD2 3.39Å; L638-F640 VanDerWaalsContact O-CE2 3.31Å; L638-F640 WeakPolarHBondContact O-CE2 3.36Å
639V95Very high90.8Very high0 Ų033.4 Ų33.40%018%0.181CC..EExtended strand (participates in β ladder)trans-102.9133.8-174.2177.30000111.7T607 A612 S616 F624 K630 H631 H632T607-V639 HydrophobicContact CG2-CG2 4.35Å; A612-V639 HydrophobicContact CB-CB 3.68Å; A612-V639 HydrophobicContact CB-CG1 3.69Å; A612-V639 HydrophobicContact CB-CG2 3.92Å; S616-V639 WeakPolarHBondContact CB-O 3.48Å; S616-V639 PolarHBondContact N-O 3.38Å; S616-V639 PolarHBondContact OG-N 2.84Å; S616-V639 PolarHBondContact OG-O 2.87Å; F624-V639 HydrophobicContact CE2-CG1 3.79Å; F624-V639 HydrophobicContact CZ-CG1 3.8Å; K630-V639 HydrophobicContact CB-CG1 3.34Å; K630-V639 HydrophobicContact CD-CG1 4.07Å; K630-V639 HydrophobicContact CG-CG1 4.25Å; H631-V639 CarbonylContact O-C 3.53Å; H631-V639 WeakPolarHBondContact O-CA 3.06Å; H632-V639 WeakPolarHBondContact NE2-CG2 3.3Å
640F94.6Very high91Very high10 Ų1034.3 Ų34.34%0.04419%0.189CC..EExtended strand (participates in β ladder)trans-136.1159.7-174-61.4-91.2000111.5N617 H631 C633 L638 C644 A645 C665N617-F640 HydrophobicContact CB-CD1 4.06Å; N617-F640 HydrophobicContact CB-CE1 4.11Å; H631-F640 PolarHBondContact N-O 2.95Å; H631-F640 PolarHBondContact O-N 3.32Å; C633-F640 HydrophobicContact CB-CD2 4.03Å; C633-F640 HydrophobicContact CB-CE2 3.63Å; L638-F640 HydrophobicContact CB-CE2 3.63Å; L638-F640 HydrophobicContact CB-CZ 3.93Å; L638-F640 VanDerWaalsContact O-CD2 3.29Å; L638-F640 WeakPolarHBondContact O-CD2 3.39Å; L638-F640 VanDerWaalsContact O-CE2 3.31Å; L638-F640 WeakPolarHBondContact O-CE2 3.36Å; F640-C644 HydrophobicContact CB-CB 4Å; F640-C644 HydrophobicContact CD1-CB 4Å; F640-C644 HydrophobicContact CG-CB 4.42Å; F640-A645 HydrophobicContact CB-CB 3.84Å; F640-C665 HydrophobicContact CD1-CB 4.04Å; F640-C665 HydrophobicContact CD2-CB 3.91Å; F640-C665 HydrophobicContact CE1-CB 3.65Å; F640-C665 HydrophobicContact CE2-CB 3.51Å; F640-C665 HydrophobicContact CG-CB 4.17Å; F640-C665 HydrophobicContact CZ-CB 3.38Å
641C89.5Confident91.1Very high12 Ų1233.5 Ų33.58%0.08119%0.185CC..  trans-73.316416769.30000111.1C615 F624 N643 C644 A645C615-C641 HydrophobicContact CB-CB 4.46Å; F624-C641 HydrophobicContact CE1-CB 3.95Å; C641-N643 VanDerWaalsContact C-N 3.25Å; C641-N643 PolarHBondContact O-N 3.14Å; C641-C644 PolarHBondContact O-N 3.13Å; C641-C644 VanDerWaalsContact SG-SG 3.65Å; C641-A645 PolarHBondContact O-N 3.24Å; C641-A645 VanDerWaalsContact O-N 3.09Å
642S84.6Confident91Very high57 Ų5733.6 Ų33.640%0.39919%0.188SC..THydrogen-bonded Turntrans-51.8-40.8-179.156.70000113.4H631 S646H631-S642 PolarHBondContact CD2-N 2.84Å; H631-S642 WeakPolarHBondContact NE2-CA 3.5Å; H631-S642 WeakPolarHBondContact NE2-CB 3.5Å; S642-S646 PolarHBondContact O-N 3.25Å
643N85Confident90.8Very high117 Ų11733.3 Ų33.363%0.62619%0.187SC*.THydrogen-bonded Turntrans-66.3-40.7177.9-67.6-23.7000112.4C641 S646C641-N643 VanDerWaalsContact C-N 3.25Å; C641-N643 PolarHBondContact O-N 3.14Å; N643-S646 PolarHBondContact O-OG 3.42Å
644C90.5Very high90.5Very high12 Ų1233.6 Ų33.68%0.08119%0.188CC..THydrogen-bonded Turntrans-81.9-11.2-176.2-71.50000114.2N617 F640 C641 W647 C665N617-C644 HydrophobicContact CB-CB 4.16Å; N617-C644 PolarHBondContact ND2-SG 2.97Å; N617-C644 VanDerWaalsContact ND2-SG 3.41Å; F640-C644 HydrophobicContact CB-CB 4Å; F640-C644 HydrophobicContact CD1-CB 4Å; F640-C644 HydrophobicContact CG-CB 4.42Å; C641-C644 PolarHBondContact O-N 3.13Å; C641-C644 VanDerWaalsContact SG-SG 3.65Å; C644-W647 WeakPolarHBondContact O-CZ3 3.49Å; C644-C665 WeakPolarHBondContact O-CA 3.49Å
645A87.9Confident90Very high7 Ų738.5 Ų38.56%0.05822%0.215CC..THydrogen-bonded Turntrans-123.431.2174.800000112.5H631 F640 C641 W647H631-A645 HydrophobicContact CB-CB 3.58Å; F640-A645 HydrophobicContact CB-CB 3.84Å; C641-A645 PolarHBondContact O-N 3.24Å; C641-A645 VanDerWaalsContact O-N 3.09Å; A645-W647 VanDerWaalsContact C-N 3.33Å
646S83.3Confident89.1Confident69 Ų6939 Ų3948%0.48322%0.218SC..  trans-76-19.3-179.853.60000113.8S642 N643S642-S646 PolarHBondContact O-N 3.25Å; N643-S646 PolarHBondContact O-OG 3.42Å
647W88.6Confident88Confident83 Ų8341.1 Ų41.131%0.31424%0.239SC..EExtended strand (participates in β ladder)trans-75.7146.2-179.7-61.8-90.5000112.1C644 A645 P663 V664 Q666 N669C644-W647 WeakPolarHBondContact O-CZ3 3.49Å; A645-W647 VanDerWaalsContact C-N 3.33Å; W647-P663 WeakPolarHBondContact O-CA 3.45Å; W647-V664 HydrophobicContact CB-CG2 3.96Å; W647-V664 PolarHBondContact O-N 2.93Å; W647-Q666 HydrophobicContact CD2-CB 4.48Å; W647-Q666 HydrophobicContact CE3-CB 3.99Å; W647-Q666 HydrophobicContact CH2-CB 3.62Å; W647-Q666 HydrophobicContact CH2-CG 3.75Å; W647-Q666 HydrophobicContact CZ2-CB 4.11Å; W647-Q666 HydrophobicContact CZ2-CG 3.82Å; W647-Q666 HydrophobicContact CZ3-CB 3.55Å; W647-Q666 HydrophobicContact CZ3-CG 4.19Å; W647-N669 HydrophobicContact CB-CB 4.04Å; W647-N669 VanDerWaalsContact CD1-ND2 3.35Å; W647-N669 HydrophobicContact CG-CB 4.14Å
648K89Confident86.9Confident111 Ų11149.9 Ų49.948%0.48328%0.277SS..EExtended strand (participates in β ladder)trans-123.2134.9172.5-61.4-175.2-176.7179.60109.9R469 P661 V662R469-K648 PolarHBondContact O-NZ 3.31Å; K648-P661 HydrophobicContact CB-CB 3.86Å; K648-V662 VanDerWaalsContact CA-O 3.3Å; K648-V662 WeakPolarHBondContact CA-O 3.36Å
649A90.2Very high86.1Confident13 Ų1348 Ų4811%0.10727%0.273CS..EExtended strand (participates in β ladder)trans-142.7149.4177.600000110.5P661 V662 V664 L672A649-P661 WeakPolarHBondContact O-CA 3.42Å; A649-V662 PolarHBondContact N-O 3.06Å; A649-V662 WeakPolarHBondContact O-CG2 3.35Å; A649-V662 PolarHBondContact O-N 3.17Å; A649-V664 HydrophobicContact CB-CG1 4.4Å; A649-V664 HydrophobicContact CB-CG2 3.82Å; A649-L672 HydrophobicContact CB-CD1 3.78Å
650V89.7Confident85.7Confident44 Ų4452.7 Ų52.727%0.26729%0.29SS..  trans-76.8123.8165.7177.70000107.2A659 P661V650-A659 HydrophobicContact CG1-CB 3.77Å; V650-P661 HydrophobicContact CG2-CG 4.1Å
651L91.9Very high85.4Confident0 Ų056 Ų560%031%0.312CS..  trans-79.6131.6177.4-56.8-176.7000108.9T601 V602 W634 C635 G653 H654 D655 V662 V664 L672T601-L651 WeakPolarHBondContact O-CD1 3.16Å; V602-L651 HydrophobicContact CG2-CB 4.06Å; V602-L651 HydrophobicContact CG2-CD1 4Å; W634-L651 HydrophobicContact CB-CD1 3.79Å; C635-L651 HydrophobicContact CB-CD2 3.98Å; L651-G653 PolarHBondContact O-N 3.15Å; L651-H654 HydrophobicContact CB-CB 4.35Å; L651-H654 CarbonylContact O-C 3.37Å; L651-H654 WeakPolarHBondContact O-CA 3.36Å; L651-H654 PolarHBondContact O-N 2.95Å; L651-D655 PolarHBondContact O-N 2.84Å; L651-V662 HydrophobicContact CD1-CG2 3.82Å; L651-V662 HydrophobicContact CD2-CG2 4.3Å; L651-V662 HydrophobicContact CG-CG2 3.68Å; L651-V664 HydrophobicContact CD2-CG1 3.79Å; L651-L672 HydrophobicContact CD2-CD1 3.6Å; L651-L672 HydrophobicContact CD2-CD2 4.44Å
652P89.3Confident85.5Confident28 Ų2855.5 Ų55.518%0.18231%0.309CS..G310 helixtrans-51.3-38.3174.3-29.934000112.9F536 T601 H654 D655 L672 F675F536-P652 WeakPolarHBondContact CE2-O 3.31Å; F536-P652 WeakPolarHBondContact CZ-O 3.46Å; T601-P652 HydrophobicContact CG2-CB 4.11Å; T601-P652 HydrophobicContact CG2-CG 3.99Å; P652-H654 PolarHBondContact O-N 3.05Å; P652-H654 VanDerWaalsContact O-N 3.17Å; P652-D655 WeakPolarHBondContact O-CB 3.43Å; P652-D655 PolarHBondContact O-N 2.76Å; P652-D655 VanDerWaalsContact O-N 3.16Å; P652-L672 VanDerWaalsContact CD-CD2 3.48Å; P652-L672 HydrophobicContact CG-CD2 4.09Å; P652-F675 HydrophobicContact CB-CD1 4.47Å; P652-F675 HydrophobicContact CB-CE1 4.02Å; P652-F675 HydrophobicContact CG-CD1 3.79Å; P652-F675 HydrophobicContact CG-CE1 3.85Å
653G88.9Confident85.8Confident0 Ų053.7 Ų53.70%030%0.296CS..G310 helixtrans-69.6-1.6174.900000115.9H533 F536 T601 L651H533-G653 PolarHBondContact ND1-O 3.23Å; F536-G653 WeakPolarHBondContact CB-O 3.21Å; F536-G653 VanDerWaalsContact CD1-O 3.32Å; F536-G653 WeakPolarHBondContact CD1-O 3.36Å; F536-G653 WeakPolarHBondContact CG-O 3.48Å; T601-G653 PolarHBondContact OG1-N 2.87Å; L651-G653 PolarHBondContact O-N 3.15Å
654H89.3Confident86.2Confident6 Ų648.1 Ų48.13%0.02827%0.267CS..G310 helixtrans-1199.7173.1-62.4165.8000112.1S529 V602 W634 L651 P652 C656 A659S529-H654 PolarHBondContact O-NE2 2.82Å; S529-H654 PolarHBondContact OG-CE1 2.8Å; S529-H654 PolarHBondContact OG-NE2 2.82Å; S529-H654 VanDerWaalsContact OG-NE2 3.16Å; V602-H654 WeakPolarHBondContact CG1-NE2 3.31Å; W634-H654 AromaticContact CE3-CE1 3.91Å; L651-H654 HydrophobicContact CB-CB 4.35Å; L651-H654 CarbonylContact O-C 3.37Å; L651-H654 WeakPolarHBondContact O-CA 3.36Å; L651-H654 PolarHBondContact O-N 2.95Å; P652-H654 PolarHBondContact O-N 3.05Å; P652-H654 VanDerWaalsContact O-N 3.17Å; H654-C656 PolarHBondContact O-N 2.87Å; H654-A659 WeakPolarHBondContact O-CB 3.23Å
655D82.5Confident86.4Confident106 Ų10647.8 Ų47.857%0.56726%0.264SS*.  trans-72.280.6-175.9-170.224.9000110.9F536 L651 P652F536-D655 WeakPolarHBondContact CD2-O 3.25Å; F536-D655 HydrophobicContact CE2-CB 4.17Å; L651-D655 PolarHBondContact O-N 2.84Å; P652-D655 WeakPolarHBondContact O-CB 3.43Å; P652-D655 PolarHBondContact O-N 2.76Å; P652-D655 VanDerWaalsContact O-N 3.16Å
656C76Confident86.5Confident20 Ų2051.4 Ų51.414%0.13528%0.28CS..SBendtrans-124.8175.6175.469.30000109.4H654 F658 A659H654-C656 PolarHBondContact O-N 2.87Å; C656-F658 PolarHBondContact O-N 2.98Å; C656-A659 VanDerWaalsContact O-CB 3.28Å; C656-A659 WeakPolarHBondContact O-CB 3.47Å; C656-A659 PolarHBondContact O-N 2.85Å
657A72.7Confident87Confident93 Ų9356.7 Ų56.777%0.76929%0.294SS*.THydrogen-bonded Turntrans-54-19.3-178.200000114.8
658F70.2Confident87.2Confident186 Ų18653.3 Ų53.382%0.81628%0.283SS*.THydrogen-bonded Turntrans-114.621.6-179.9-53-74.1000113.3C656 R660C656-F658 PolarHBondContact O-N 2.98Å; F658-R660 PolarHBondContact O-N 3.1Å
659A79.4Confident87.4Confident35 Ų3549 Ų4929%0.28927%0.266SS..  trans-57.3124.2-179.700000111V650 H654 C656V650-A659 HydrophobicContact CG1-CB 3.77Å; H654-A659 WeakPolarHBondContact O-CB 3.23Å; C656-A659 VanDerWaalsContact O-CB 3.28Å; C656-A659 WeakPolarHBondContact O-CB 3.47Å; C656-A659 PolarHBondContact O-N 2.85Å
660R86.2Confident87.4Confident97 Ų9751.9 Ų51.937%0.36628%0.284SS..  trans-118.8147.7178.669.6-179.8-176.1143.61.8111.3E472 F658 V662E472-R660 VanDerWaalsContact CD-NH1 3.31Å; E472-R660 IonicContact OE1-CZ 2.65Å; E472-R660 IonicContact OE1-NH1 3.55Å; E472-R660 PolarHBondContact OE1-NH1 2.89Å; E472-R660 IonicContact OE2-CZ 3.56Å; E472-R660 IonicContact OE2-NH1 3.51Å; E472-R660 PolarHBondContact OE2-NH1 3.26Å; E472-R660 VanDerWaalsContact OE2-NH1 3.12Å; E472-R660 IonicContact OE2-NH2 2.69Å; E472-R660 PolarHBondContact OE2-NH2 3.43Å; E472-R660 VanDerWaalsContact OE2-NH2 3.13Å; F658-R660 PolarHBondContact O-N 3.1Å; R660-V662 HydrophobicContact CG-CG1 4.07Å; R660-V662 PolarHBondContact O-N 2.85Å
661P89.2Confident87.4Confident79 Ų7955.3 Ų55.351%0.51330%0.295SS..  trans-62.5128.4169.6-21.332.8000111K648 A649 V650K648-P661 HydrophobicContact CB-CB 3.86Å; A649-P661 WeakPolarHBondContact O-CA 3.42Å; V650-P661 HydrophobicContact CG2-CG 4.1Å
662V90.7Very high87.2Confident3 Ų355.7 Ų55.72%0.01830%0.297CS..EExtended strand (participates in β ladder)trans-122156.5-178.9-65.30000111.5W634 K648 A649 L651 R660 V664W634-V662 HydrophobicContact CB-CB 4.32Å; W634-V662 HydrophobicContact CB-CG2 3.82Å; W634-V662 HydrophobicContact CD2-CB 3.64Å; W634-V662 HydrophobicContact CD2-CG1 3.93Å; W634-V662 HydrophobicContact CD2-CG2 4Å; W634-V662 HydrophobicContact CE3-CB 3.64Å; W634-V662 HydrophobicContact CE3-CG1 3.46Å; W634-V662 VanDerWaalsContact CE3-CG1 3.46Å; W634-V662 HydrophobicContact CE3-CG2 3.88Å; W634-V662 HydrophobicContact CG-CB 3.96Å; W634-V662 HydrophobicContact CG-CG2 4.02Å; W634-V662 HydrophobicContact CH2-CG1 4.05Å; W634-V662 HydrophobicContact CZ2-CG1 4.43Å; W634-V662 HydrophobicContact CZ3-CB 4.21Å; W634-V662 HydrophobicContact CZ3-CG1 3.54Å; K648-V662 VanDerWaalsContact CA-O 3.3Å; K648-V662 WeakPolarHBondContact CA-O 3.36Å; A649-V662 PolarHBondContact N-O 3.06Å; A649-V662 WeakPolarHBondContact O-CG2 3.35Å; A649-V662 PolarHBondContact O-N 3.17Å; L651-V662 HydrophobicContact CD1-CG2 3.82Å; L651-V662 HydrophobicContact CD2-CG2 4.3Å; L651-V662 HydrophobicContact CG-CG2 3.68Å; R660-V662 HydrophobicContact CG-CG1 4.07Å; R660-V662 PolarHBondContact O-N 2.85Å; V662-V664 PolarHBondContact O-N 2.93Å
663P90.7Very high87.1Confident19 Ų1958.5 Ų58.512%0.12331%0.31CS..EExtended strand (participates in β ladder)trans-58.3129-179.7-24.734.6000113.3W634 W647W634-P663 PolarHBondContact N-O 2.92Å; W647-P663 WeakPolarHBondContact O-CA 3.45Å
664V93.7Very high86.8Confident0 Ų060.9 Ų60.90%033%0.33CS..EExtended strand (participates in β ladder)trans-134.5148.2174.9-67.80000111.2C635 W647 A649 L651 V662 C668 N669 L672C635-V664 HydrophobicContact CB-CG1 4.1Å; W647-V664 HydrophobicContact CB-CG2 3.96Å; W647-V664 PolarHBondContact O-N 2.93Å; A649-V664 HydrophobicContact CB-CG1 4.4Å; A649-V664 HydrophobicContact CB-CG2 3.82Å; L651-V664 HydrophobicContact CD2-CG1 3.79Å; V662-V664 PolarHBondContact O-N 2.93Å; V664-C668 HydrophobicContact CB-CB 4.32Å; V664-N669 HydrophobicContact CG2-CB 3.87Å; V664-L672 HydrophobicContact CG1-CD1 4.09Å
665C94.4Very high86Confident5 Ų563.1 Ų63.13%0.03434%0.34CS..  trans-73.9160.4172.6750000110.6C633 F640 C644 K667 C668 N669C633-C665 HydrophobicContact CB-CB 4Å; C633-C665 PolarHBondContact SG-N 3.45Å; F640-C665 HydrophobicContact CD1-CB 4.04Å; F640-C665 HydrophobicContact CD2-CB 3.91Å; F640-C665 HydrophobicContact CE1-CB 3.65Å; F640-C665 HydrophobicContact CE2-CB 3.51Å; F640-C665 HydrophobicContact CG-CB 4.17Å; F640-C665 HydrophobicContact CZ-CB 3.38Å; C644-C665 WeakPolarHBondContact O-CA 3.49Å; C665-K667 VanDerWaalsContact C-N 3.29Å; C665-K667 PolarHBondContact O-N 2.78Å; C665-C668 PolarHBondContact O-N 3.13Å; C665-C668 VanDerWaalsContact O-N 3.14Å; C665-C668 PolarHBondContact SG-N 2.95Å; C665-N669 WeakPolarHBondContact O-CB 3.26Å; C665-N669 PolarHBondContact O-N 2.88Å
666Q91.4Very high85.4Confident83 Ų8363.4 Ų63.439%0.38834%0.338SS..Hα-helixtrans-50.6-46.3179.7-167.6178.3-1.700113.2W647 C668 N669 C670W647-Q666 HydrophobicContact CD2-CB 4.48Å; W647-Q666 HydrophobicContact CE3-CB 3.99Å; W647-Q666 HydrophobicContact CH2-CB 3.62Å; W647-Q666 HydrophobicContact CH2-CG 3.75Å; W647-Q666 HydrophobicContact CZ2-CB 4.11Å; W647-Q666 HydrophobicContact CZ2-CG 3.82Å; W647-Q666 HydrophobicContact CZ3-CB 3.55Å; W647-Q666 HydrophobicContact CZ3-CG 4.19Å; Q666-C668 PolarHBondContact O-N 3.2Å; Q666-N669 WeakPolarHBondContact O-CB 3.44Å; Q666-N669 PolarHBondContact O-N 3.35Å; Q666-C670 PolarHBondContact O-N 2.87Å; Q666-C670 PolarHBondContact O-SG 2.89Å; Q666-C670 VanDerWaalsContact O-SG 3.36Å
667K92.7Very high85.3Confident179 Ų17971.1 Ų71.178%0.77837%0.369SS*.Hα-helixtrans-60.8-47.2-179.5-177.1-179.1178.3-178.70111.6C665 C670 K671C665-K667 VanDerWaalsContact C-N 3.29Å; C665-K667 PolarHBondContact O-N 2.78Å; K667-C670 PolarHBondContact O-N 3.03Å; K667-K671 PolarHBondContact O-N 2.82Å; K667-K671 VanDerWaalsContact O-N 3.07Å
668C94.3Very high84.5Confident12 Ų1273.4 Ų73.48%0.08137%0.367CS..Hα-helixtrans-66.2-40.2177-72.60000111.4C633 C635 V664 C665 Q666 C670 K671 L672C633-C668 VanDerWaalsContact SG-SG 3.67Å; C635-C668 HydrophobicContact CB-CB 3.72Å; V664-C668 HydrophobicContact CB-CB 4.32Å; C665-C668 PolarHBondContact O-N 3.13Å; C665-C668 VanDerWaalsContact O-N 3.14Å; C665-C668 PolarHBondContact SG-N 2.95Å; Q666-C668 PolarHBondContact O-N 3.2Å; C668-C670 PolarHBondContact O-N 3.01Å; C668-K671 PolarHBondContact O-N 3.48Å; C668-L672 WeakPolarHBondContact O-CB 3.48Å; C668-L672 WeakPolarHBondContact O-CG 3.41Å; C668-L672 PolarHBondContact O-N 3.45Å
669N92.2Very high83.6Confident22 Ų2272.6 Ų72.612%0.11837%0.369CS..Hα-helixtrans-59.1-45.8176-167.761.5000111.8W647 V664 C665 Q666 K671 L672 L673W647-N669 HydrophobicContact CB-CB 4.04Å; W647-N669 VanDerWaalsContact CD1-ND2 3.35Å; W647-N669 HydrophobicContact CG-CB 4.14Å; V664-N669 HydrophobicContact CG2-CB 3.87Å; C665-N669 WeakPolarHBondContact O-CB 3.26Å; C665-N669 PolarHBondContact O-N 2.88Å; Q666-N669 WeakPolarHBondContact O-CB 3.44Å; Q666-N669 PolarHBondContact O-N 3.35Å; N669-K671 PolarHBondContact O-N 3.47Å; N669-L672 PolarHBondContact O-N 3.43Å; N669-L673 WeakPolarHBondContact O-CG 3.39Å; N669-L673 PolarHBondContact O-N 3.06Å
670C90.7Very high83.8Confident73 Ų7374.5 Ų74.549%0.49337%0.373SS..Hα-helixtrans-61.2-42.7174.8-68.10000112.5Q666 K667 C668 L673 A674Q666-C670 PolarHBondContact O-N 2.87Å; Q666-C670 PolarHBondContact O-SG 2.89Å; Q666-C670 VanDerWaalsContact O-SG 3.36Å; K667-C670 PolarHBondContact O-N 3.03Å; C668-C670 PolarHBondContact O-N 3.01Å; C670-L673 PolarHBondContact O-N 3.28Å; C670-A674 PolarHBondContact O-N 3.28Å; C670-A674 VanDerWaalsContact O-N 3.08Å
671K89.2Confident83.7Confident116 Ų11673.3 Ų73.350%0.50437%0.374SS..Hα-helixtrans-60.1-45.1175.2-176.1-173.3175.4-169.80111.4D600 K667 C668 N669 A674 F675D600-K671 PolarHBondContact O-NZ 2.96Å; K667-K671 PolarHBondContact O-N 2.82Å; K667-K671 VanDerWaalsContact O-N 3.07Å; C668-K671 PolarHBondContact O-N 3.48Å; N669-K671 PolarHBondContact O-N 3.47Å; K671-A674 WeakPolarHBondContact O-CB 3.17Å; K671-A674 PolarHBondContact O-N 2.92Å; K671-F675 PolarHBondContact O-N 3.39Å
672L88.5Confident83.4Confident8 Ų872.9 Ų72.94%0.04237%0.366CS..Hα-helixtrans-66.9-41.4-179.2-69.1169.8000112.3A649 L651 P652 V664 C668 N669 A674 F675 Q676A649-L672 HydrophobicContact CB-CD1 3.78Å; L651-L672 HydrophobicContact CD2-CD1 3.6Å; L651-L672 HydrophobicContact CD2-CD2 4.44Å; P652-L672 VanDerWaalsContact CD-CD2 3.48Å; P652-L672 HydrophobicContact CG-CD2 4.09Å; V664-L672 HydrophobicContact CG1-CD1 4.09Å; C668-L672 WeakPolarHBondContact O-CB 3.48Å; C668-L672 WeakPolarHBondContact O-CG 3.41Å; C668-L672 PolarHBondContact O-N 3.45Å; N669-L672 PolarHBondContact O-N 3.43Å; L672-A674 VanDerWaalsContact C-N 3.28Å; L672-A674 PolarHBondContact O-N 2.98Å; L672-F675 WeakPolarHBondContact O-CB 3.21Å; L672-F675 PolarHBondContact O-N 3.14Å; L672-Q676 PolarHBondContact O-N 2.83Å
673L86.8Confident82.9Confident86 Ų8677.1 Ų77.145%0.4539%0.386SS..Hα-helixtrans-63.9-33.1174.3-73.6174000112.4N669 C670 K677N669-L673 WeakPolarHBondContact O-CG 3.39Å; N669-L673 PolarHBondContact O-N 3.06Å; C670-L673 PolarHBondContact O-N 3.28Å; L673-K677 WeakPolarHBondContact O-CG 3.16Å
674A82.2Confident82.4Confident51 Ų5180.7 Ų80.742%0.42140%0.403SS..Hα-helixtrans-69.1-41.9173.300000111.4C670 K671 L672 Q676 K677 I678C670-A674 PolarHBondContact O-N 3.28Å; C670-A674 VanDerWaalsContact O-N 3.08Å; K671-A674 WeakPolarHBondContact O-CB 3.17Å; K671-A674 PolarHBondContact O-N 2.92Å; L672-A674 VanDerWaalsContact C-N 3.28Å; L672-A674 PolarHBondContact O-N 2.98Å; A674-Q676 PolarHBondContact O-N 2.83Å; A674-K677 PolarHBondContact O-N 2.82Å; A674-K677 VanDerWaalsContact O-N 3.16Å; A674-I678 WeakPolarHBondContact O-CG1 3.28Å
675F71.4Confident81.7Confident53 Ų5386.1 Ų86.123%0.23243%0.429CS..Hα-helixtrans-60.9-41.8176.7-167.2-101.3000112.4P652 K671 L672 K677 I678 I679P652-F675 HydrophobicContact CB-CD1 4.47Å; P652-F675 HydrophobicContact CB-CE1 4.02Å; P652-F675 HydrophobicContact CG-CD1 3.79Å; P652-F675 HydrophobicContact CG-CE1 3.85Å; K671-F675 PolarHBondContact O-N 3.39Å; L672-F675 WeakPolarHBondContact O-CB 3.21Å; L672-F675 PolarHBondContact O-N 3.14Å; F675-K677 PolarHBondContact O-N 2.99Å; F675-I678 PolarHBondContact O-N 3.23Å; F675-I678 VanDerWaalsContact O-N 3.11Å; F675-I679 HydrophobicContact CD1-CD1 3.82Å; F675-I679 HydrophobicContact CE1-CD1 3.38Å; F675-I679 HydrophobicContact CE1-CG1 4.28Å; F675-I679 HydrophobicContact CZ-CD1 4.08Å; F675-I679 PolarHBondContact O-N 3.02Å
676Q71.7Confident80.8Confident112 Ų11291.9 Ų91.952%0.52346%0.458SS..THydrogen-bonded Turntrans-65.9-16.3176-75.2-179.6-23.700114.9L672 A674L672-Q676 PolarHBondContact O-N 2.83Å; A674-Q676 PolarHBondContact O-N 2.83Å
677K72.3Confident80Confident181 Ų18192.5 Ų92.579%0.78746%0.463SS*.THydrogen-bonded Turntrans-88.6-14.9174.3-71.6179.3179.6-175.50113L673 A674 F675L673-K677 WeakPolarHBondContact O-CG 3.16Å; A674-K677 PolarHBondContact O-N 2.82Å; A674-K677 VanDerWaalsContact O-N 3.16Å; F675-K677 PolarHBondContact O-N 2.99Å
678I57.5Low78.9Confident141 Ų14185.3 Ų85.372%0.72344%0.437SS*.THydrogen-bonded Turntrans-91.8-37.6-177.7-65.2168.1000110.4A674 F675A674-I678 WeakPolarHBondContact O-CG1 3.28Å; F675-I678 PolarHBondContact O-N 3.23Å; F675-I678 VanDerWaalsContact O-N 3.11Å
679I49.9Very low77.5Confident169 Ų16992 Ų9287%0.86747%0.469SS*.  trans-70.80164.6-58.4176.2000108.7F675F675-I679 HydrophobicContact CD1-CD1 3.82Å; F675-I679 HydrophobicContact CE1-CD1 3.38Å; F675-I679 HydrophobicContact CE1-CG1 4.28Å; F675-I679 HydrophobicContact CZ-CD1 4.08Å; F675-I679 PolarHBondContact O-N 3.02Å

Retrieved 679 of 679 residues in 419.9 ms (Link to these results)