A0A077Z6N4_TRITR Loading...

2-oxoisovalerate dehydrogenase subunit alpha

The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

AlphaFold DB , UniProt , Accession A0A077Z6N4, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 604 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M37.2Very low40.3Very low234 Ų234167.2 Ų167.2100%1.15385%0.851SS**  0116.70-74.1-174-151.300107
2W34.9Very low40.3Very low219 Ų219163.2 Ų163.283%0.8385%0.845SS**  cis-153.1134.83.5-108.964.6000106
3F38.7Very low40.2Very low163 Ų163160.2 Ų160.272%0.71585%0.845SS**  trans25142.7142.6-68.8-93.9000120.5
4H41.8Very low40Very low172 Ų172161.2 Ų161.280%0.79685%0.849SS**  cis-169.5145.147.6-125.5-61.3000111.6
5R39.7Very low40.1Very low234 Ų234159.5 Ų159.588%0.88385%0.847SS**  trans-66.8147166.9-72.5174173.5-172.5-3.5112.5
6L49.6Very low40.1Very low183 Ų183156.7 Ų156.796%0.95885%0.845SS**  trans-120.9111146.8-83.1166.2000108.3
7G38.2Very low40.1Very low79 Ų79151.5 Ų151.581%0.81484%0.837SS**  trans-105.4133.3166.100000109.1
8G44.2Very low40.1Very low80 Ų80153.8 Ų153.883%0.82584%0.837SS**  trans-129.6112.1172.200000110
9Q41.3Very low40.1Very low176 Ų176151.6 Ų151.682%0.82284%0.842SS**  trans-27.8131.5167.9-75.2172.9-23.200116.6
10L38.5Very low40.4Very low141 Ų141150.2 Ų150.274%0.73884%0.837SS**  102.611584.4-83.8169000111.4
11L39.2Very low40.5Very low158 Ų158145.8 Ų145.883%0.82783%0.825SS**  164.6120.4126.2-104128.5000110.1
12P40Very low41Very low119 Ų119145.7 Ų145.777%0.77381%0.812SS**  trans-102.2126.9166.533.2-22.2000110.8
13C39.8Very low41.7Very low125 Ų125147 Ų14785%0.84582%0.817SS**  trans-121.8113.2162-90.70000109.3
14L37.3Very low42.3Very low174 Ų174142.1 Ų142.191%0.91180%0.8SS**  trans-65.7125167.1-77.7146.2000110.3
15V41.1Very low43.2Very low135 Ų135139.7 Ų139.782%0.81879%0.793SS**  trans-149.2128.1142.1-175.20000109.1
16S41Very low45.2Very low115 Ų115132.7 Ų132.780%0.80478%0.777SS**  trans-47141.7172.654.30000115.2
17G38.5Very low47.1Very low69 Ų69128.4 Ų128.471%0.71176%0.755SS**  trans163.3109.5159.200000116
18K41.3Very low49.5Very low192 Ų192127.2 Ų127.284%0.83574%0.738SS**  trans72111.5157.7-60.6-176.8177.9179.70117.3V20K18-V20 VanDerWaalsContact C-N 3.34Å; K18-V20 HydrophobicContact CB-CG2 4.16Å; K18-V20 PolarHBondContact O-N 2.94Å
19A39.7Very low51.7Low113 Ų113129.1 Ų129.193%0.93473%0.725SS**  trans-55.898.3152.600000108.8
20V46.9Very low54.1Low122 Ų122124 Ų12474%0.73970%0.703SS**  trans-99.3113.7168.1-179.20000105.7K18 R22K18-V20 VanDerWaalsContact C-N 3.34Å; K18-V20 HydrophobicContact CB-CG2 4.16Å; K18-V20 PolarHBondContact O-N 2.94Å; V20-R22 PolarHBondContact O-N 3.02Å
21G41.2Very low56.7Low58 Ų58119.2 Ų119.260%0.59868%0.678SS**  trans-52.3112.4174.800000109.7W23G21-W23 PolarHBondContact O-N 2.93Å
22R47.1Very low59.2Low233 Ų233114 Ų11488%0.87965%0.654SS**  trans-74.883.6169.6-143.5-179.8-167.2-174.82.1105.7V20 V24V20-R22 PolarHBondContact O-N 3.02Å; R22-V24 PolarHBondContact O-N 2.83Å
23W50.2Low61.7Low246 Ų246113 Ų11393%0.93264%0.639SS**  trans-64.388158.4-71.490.1000105.6G21 N25G21-W23 PolarHBondContact O-N 2.93Å; W23-N25 PolarHBondContact O-N 3.27Å
24V52Low64.2Low60 Ų60110 Ų11036%0.36461%0.612SS.*  trans-51.4124162.2-179.60000105R22 T26 E29R22-V24 PolarHBondContact O-N 2.83Å; V24-T26 HydrophobicContact CB-CG2 4.12Å; V24-T26 HydrophobicContact CG1-CG2 4.11Å; V24-T26 WeakPolarHBondContact O-CG2 3.46Å; V24-T26 PolarHBondContact O-N 2.76Å; V24-E29 HydrophobicContact CG1-CG 4.34Å; V24-E29 WeakPolarHBondContact CG1-OE1 3.1Å; V24-E29 WeakPolarHBondContact CG1-OE2 3.27Å
25N60Low66.9Low121 Ų121102.7 Ų102.765%0.64758%0.576SS**  trans-74.377.7173.6-139.8-0.7000105.7W23 D27 A28 E29W23-N25 PolarHBondContact O-N 3.27Å; N25-D27 PolarHBondContact O-N 3.07Å; N25-D27 VanDerWaalsContact O-N 3.14Å; N25-A28 HydrophobicContact CB-CB 4.33Å; N25-A28 PolarHBondContact O-N 2.88Å; N25-A28 VanDerWaalsContact O-N 3.14Å; N25-E29 PolarHBondContact O-N 3.34Å; N25-E29 VanDerWaalsContact O-N 3.07Å
26T82Confident69.3Low88 Ų88102.6 Ų102.654%0.5456%0.564SS.*Hα-helixtrans-55.4-39.2-161.849.10000111.1V24 L30V24-T26 HydrophobicContact CB-CG2 4.12Å; V24-T26 HydrophobicContact CG1-CG2 4.11Å; V24-T26 WeakPolarHBondContact O-CG2 3.46Å; V24-T26 PolarHBondContact O-N 2.76Å; T26-L30 WeakPolarHBondContact O-CB 3.5Å; T26-L30 PolarHBondContact O-N 3.14Å
27D90Very high71.7Confident92 Ų92100.7 Ų100.749%0.49255%0.547SS..Hα-helixtrans-76.1-38.2-174.7-645000111.7N25 L30 L31 F46N25-D27 PolarHBondContact O-N 3.07Å; N25-D27 VanDerWaalsContact O-N 3.14Å; D27-L30 PolarHBondContact O-N 3.14Å; D27-L31 WeakPolarHBondContact O-CB 3.35Å; D27-L31 VanDerWaalsContact O-CG 3.23Å; D27-L31 WeakPolarHBondContact O-CG 3.46Å; D27-L31 PolarHBondContact O-N 2.81Å; D27-F46 HydrophobicContact CB-CD2 4.37Å; D27-F46 HydrophobicContact CB-CE2 4.04Å
28A88.8Confident74.2Confident55 Ų55103.5 Ų103.546%0.45554%0.54SS..Hα-helixtrans-67.9-40.8176.400000111.5N25 L30 S32N25-A28 HydrophobicContact CB-CB 4.33Å; N25-A28 PolarHBondContact O-N 2.88Å; N25-A28 VanDerWaalsContact O-N 3.14Å; A28-L30 VanDerWaalsContact C-N 3.34Å; A28-S32 WeakPolarHBondContact O-CB 3.34Å; A28-S32 PolarHBondContact O-N 3.2Å
29E89.9Confident76.4Confident119 Ų11999 Ų9956%0.55652%0.521SS*.Hα-helixtrans-65.2-40.1173.3-71-173.3-175.800111.5V24 N25 S32 H33V24-E29 HydrophobicContact CG1-CG 4.34Å; V24-E29 WeakPolarHBondContact CG1-OE1 3.1Å; V24-E29 WeakPolarHBondContact CG1-OE2 3.27Å; N25-E29 PolarHBondContact O-N 3.34Å; N25-E29 VanDerWaalsContact O-N 3.07Å; E29-S32 WeakPolarHBondContact O-CB 3.5Å; E29-S32 PolarHBondContact O-N 3.08Å; E29-H33 WeakPolarHBondContact O-CB 2.98Å; E29-H33 PolarHBondContact O-N 2.92Å
30L91.5Very high78.6Confident68 Ų6897.3 Ų97.336%0.35651%0.507SS..Hα-helixtrans-66.6-44.2176.9-174.261000112T26 D27 A28 S32 H33 F34 F46T26-L30 WeakPolarHBondContact O-CB 3.5Å; T26-L30 PolarHBondContact O-N 3.14Å; D27-L30 PolarHBondContact O-N 3.14Å; A28-L30 VanDerWaalsContact C-N 3.34Å; L30-S32 VanDerWaalsContact C-N 3.33Å; L30-S32 PolarHBondContact O-N 3.36Å; L30-H33 CarbonylContact O-C 3.59Å; L30-H33 WeakPolarHBondContact O-CB 3.43Å; L30-H33 PolarHBondContact O-N 2.78Å; L30-F34 HydrophobicContact CD1-CE1 3.99Å; L30-F34 HydrophobicContact CD1-CE2 3.99Å; L30-F34 HydrophobicContact CD1-CZ 3.7Å; L30-F34 HydrophobicContact CD2-CE2 4Å; L30-F34 HydrophobicContact CD2-CZ 4.18Å; L30-F34 HydrophobicContact CG-CD2 4.08Å; L30-F34 HydrophobicContact CG-CE1 4.49Å; L30-F34 HydrophobicContact CG-CE2 3.58Å; L30-F34 HydrophobicContact CG-CZ 3.82Å; L30-F34 WeakPolarHBondContact O-CB 3.39Å; L30-F34 WeakPolarHBondContact O-CD2 3.35Å; L30-F34 WeakPolarHBondContact O-CG 3.49Å; L30-F34 PolarHBondContact O-N 3.35Å; L30-F46 HydrophobicContact CD2-CE2 4.42Å; L30-F46 HydrophobicContact CD2-CZ 3.74Å; L30-F46 HydrophobicContact CG-CZ 4.1Å
31L93.4Very high80.7Confident42 Ų4297 Ų9722%0.2250%0.501CS..Hα-helixtrans-61.7-41.4172.9-72.7173.1000111.3D27 H33 F34 S35 V44 F46D27-L31 WeakPolarHBondContact O-CB 3.35Å; D27-L31 VanDerWaalsContact O-CG 3.23Å; D27-L31 WeakPolarHBondContact O-CG 3.46Å; D27-L31 PolarHBondContact O-N 2.81Å; L31-H33 VanDerWaalsContact C-N 3.33Å; L31-H33 PolarHBondContact O-N 2.79Å; L31-F34 PolarHBondContact O-N 3.5Å; L31-S35 WeakPolarHBondContact O-CB 3.29Å; L31-S35 PolarHBondContact O-N 3.33Å; L31-V44 HydrophobicContact CB-CG2 4.42Å; L31-V44 HydrophobicContact CD2-CG2 4Å; L31-V44 WeakPolarHBondContact O-CG2 3.44Å; L31-F46 HydrophobicContact CD1-CD2 3.97Å; L31-F46 HydrophobicContact CD1-CE2 4.19Å; L31-F46 HydrophobicContact CD2-CD1 4.41Å; L31-F46 HydrophobicContact CD2-CD2 3.68Å; L31-F46 HydrophobicContact CD2-CE1 4.36Å; L31-F46 HydrophobicContact CD2-CE2 3.62Å; L31-F46 HydrophobicContact CD2-CG 4.08Å; L31-F46 HydrophobicContact CD2-CZ 3.97Å; L31-F46 HydrophobicContact CG-CD2 3.79Å; L31-F46 HydrophobicContact CG-CE2 3.56Å; L31-F46 HydrophobicContact CG-CZ 4.26Å
32S91.9Very high83Confident48 Ų48101.5 Ų101.534%0.33650%0.5SS..Hα-helixtrans-62.2-42.4174-1650000111.5A28 E29 L30 K36A28-S32 WeakPolarHBondContact O-CB 3.34Å; A28-S32 PolarHBondContact O-N 3.2Å; E29-S32 WeakPolarHBondContact O-CB 3.5Å; E29-S32 PolarHBondContact O-N 3.08Å; L30-S32 VanDerWaalsContact C-N 3.33Å; L30-S32 PolarHBondContact O-N 3.36Å; S32-K36 WeakPolarHBondContact O-CB 3.23Å; S32-K36 VanDerWaalsContact O-CG 3.27Å; S32-K36 WeakPolarHBondContact O-CG 3.36Å; S32-K36 PolarHBondContact O-N 3.48Å; S32-K36 VanDerWaalsContact O-N 3.08Å; S32-K36 PolarHBondContact OG-NZ 2.62Å
33H91.9Very high85.1Confident99 Ų9996.2 Ų96.246%0.45850%0.499SS..Hα-helixtrans-63.6-44.2175.6-178.670.6000111.4E29 L30 L31 K36 T37E29-H33 WeakPolarHBondContact O-CB 2.98Å; E29-H33 PolarHBondContact O-N 2.92Å; L30-H33 CarbonylContact O-C 3.59Å; L30-H33 WeakPolarHBondContact O-CB 3.43Å; L30-H33 PolarHBondContact O-N 2.78Å; L31-H33 VanDerWaalsContact C-N 3.33Å; L31-H33 PolarHBondContact O-N 2.79Å; H33-K36 PolarHBondContact O-N 3.36Å; H33-T37 PolarHBondContact CE1-OG1 2.92Å; H33-T37 PolarHBondContact ND1-OG1 3.33Å; H33-T37 WeakPolarHBondContact O-CB 3.14Å; H33-T37 PolarHBondContact O-N 2.88Å; H33-T37 PolarHBondContact O-OG1 3.46Å
34F93.4Very high87.1Confident62 Ų6286.3 Ų86.327%0.27247%0.466SS..Hα-helixtrans-62.3-51.4177.4-72.3-31.7000112.2L30 L31 K36 T37 F38 F39 V44 F46L30-F34 HydrophobicContact CD1-CE1 3.99Å; L30-F34 HydrophobicContact CD1-CE2 3.99Å; L30-F34 HydrophobicContact CD1-CZ 3.7Å; L30-F34 HydrophobicContact CD2-CE2 4Å; L30-F34 HydrophobicContact CD2-CZ 4.18Å; L30-F34 HydrophobicContact CG-CD2 4.08Å; L30-F34 HydrophobicContact CG-CE1 4.49Å; L30-F34 HydrophobicContact CG-CE2 3.58Å; L30-F34 HydrophobicContact CG-CZ 3.82Å; L30-F34 WeakPolarHBondContact O-CB 3.39Å; L30-F34 WeakPolarHBondContact O-CD2 3.35Å; L30-F34 WeakPolarHBondContact O-CG 3.49Å; L30-F34 PolarHBondContact O-N 3.35Å; L31-F34 PolarHBondContact O-N 3.5Å; F34-K36 VanDerWaalsContact C-N 3.33Å; F34-K36 PolarHBondContact O-N 3.49Å; F34-T37 PolarHBondContact O-N 3.33Å; F34-F38 HydrophobicContact CB-CD2 4.44Å; F34-F38 AromaticContact CD1-CD2 3.59Å; F34-F38 HydrophobicContact CD1-CD2 3.59Å; F34-F38 AromaticContact CD1-CE2 3.61Å; F34-F38 HydrophobicContact CD1-CE2 3.61Å; F34-F38 HydrophobicContact CE1-CD2 4.35Å; F34-F38 HydrophobicContact CE1-CE2 4.03Å; F34-F38 HydrophobicContact CG-CD2 4.46Å; F34-F38 PolarHBondContact O-N 2.75Å; F34-F39 WeakPolarHBondContact O-CD2 3.32Å; F34-F39 PolarHBondContact O-N 3.21Å; F34-V44 HydrophobicContact CB-CG2 4.06Å; F34-F46 HydrophobicContact CD2-CE1 4.39Å; F34-F46 HydrophobicContact CD2-CZ 4.18Å; F34-F46 AromaticContact CE2-CE1 3.82Å; F34-F46 HydrophobicContact CE2-CE1 3.82Å; F34-F46 AromaticContact CE2-CZ 3.71Å; F34-F46 HydrophobicContact CE2-CZ 3.71Å
35S92.7Very high89.1Confident20 Ų2088.2 Ų88.214%0.1448%0.482CS..Hα-helixtrans-50.8-52.6176.6179.70000111.4L31 F39 A40 N41 R42L31-S35 WeakPolarHBondContact O-CB 3.29Å; L31-S35 PolarHBondContact O-N 3.33Å; S35-F39 CarbonylContact O-C 3.57Å; S35-F39 PolarHBondContact O-N 2.88Å; S35-A40 PolarHBondContact O-N 3.12Å; S35-N41 WeakPolarHBondContact O-CA 3.48Å; S35-N41 PolarHBondContact O-N 3.46Å; S35-N41 WeakPolarHBondContact OG-CA 3.18Å; S35-R42 VanDerWaalsContact CB-O 3.29Å; S35-R42 WeakPolarHBondContact CB-O 3.4Å; S35-R42 PolarHBondContact OG-O 3.41Å
36K91.9Very high90.7Very high132 Ų13287.4 Ų87.457%0.57447%0.473SS*.Hα-helixtrans-70.6-42.7-176.1-70.6172.7-179.61690113.1S32 H33 F34 N41S32-K36 WeakPolarHBondContact O-CB 3.23Å; S32-K36 VanDerWaalsContact O-CG 3.27Å; S32-K36 WeakPolarHBondContact O-CG 3.36Å; S32-K36 PolarHBondContact O-N 3.48Å; S32-K36 VanDerWaalsContact O-N 3.08Å; S32-K36 PolarHBondContact OG-NZ 2.62Å; H33-K36 PolarHBondContact O-N 3.36Å; F34-K36 VanDerWaalsContact C-N 3.33Å; F34-K36 PolarHBondContact O-N 3.49Å; K36-N41 WeakPolarHBondContact CG-OD1 3.26Å
37T91.9Very high91.2Very high75 Ų7588.4 Ų88.446%0.4648%0.479SS..Hα-helixtrans-86.5-40.6-169-48.80000112.5H33 F34H33-T37 PolarHBondContact CE1-OG1 2.92Å; H33-T37 PolarHBondContact ND1-OG1 3.33Å; H33-T37 WeakPolarHBondContact O-CB 3.14Å; H33-T37 PolarHBondContact O-N 2.88Å; H33-T37 PolarHBondContact O-OG1 3.46Å; F34-T37 PolarHBondContact O-N 3.33Å
38F90.3Very high91.4Very high128 Ų12893.6 Ų93.656%0.56150%0.5SS*.Hα-helixtrans-111.8-25.8-170.3-55-64.4000113.8F34F34-F38 HydrophobicContact CB-CD2 4.44Å; F34-F38 AromaticContact CD1-CD2 3.59Å; F34-F38 HydrophobicContact CD1-CD2 3.59Å; F34-F38 AromaticContact CD1-CE2 3.61Å; F34-F38 HydrophobicContact CD1-CE2 3.61Å; F34-F38 HydrophobicContact CE1-CD2 4.35Å; F34-F38 HydrophobicContact CE1-CE2 4.03Å; F34-F38 HydrophobicContact CG-CD2 4.46Å; F34-F38 PolarHBondContact O-N 2.75Å
39F88.2Confident91.7Very high98 Ų9898 Ų9843%0.4351%0.511SS..SBendtrans-11721.2-171.6-62.9-81.4000113.9F34 S35 N41 R42 V44F34-F39 WeakPolarHBondContact O-CD2 3.32Å; F34-F39 PolarHBondContact O-N 3.21Å; S35-F39 CarbonylContact O-C 3.57Å; S35-F39 PolarHBondContact O-N 2.88Å; F39-N41 VanDerWaalsContact C-N 3.26Å; F39-N41 PolarHBondContact O-N 2.93Å; F39-R42 HydrophobicContact CB-CB 4.17Å; F39-R42 VanDerWaalsContact O-CB 3.26Å; F39-R42 WeakPolarHBondContact O-CB 3.46Å; F39-R42 WeakPolarHBondContact O-CD 3.47Å; F39-R42 WeakPolarHBondContact O-CG 3.35Å; F39-R42 PolarHBondContact O-N 3.2Å; F39-V44 HydrophobicContact CB-CG1 4.13Å; F39-V44 HydrophobicContact CD1-CG1 4.49Å; F39-V44 HydrophobicContact CD2-CG1 3.63Å; F39-V44 HydrophobicContact CE2-CG1 4.13Å; F39-V44 HydrophobicContact CG-CG1 3.83Å
40A86.2Confident91.8Very high78 Ų78100.9 Ų100.965%0.64553%0.527SS*.THydrogen-bonded Turntrans50.942.7176.100000113.6S35 R42S35-A40 PolarHBondContact O-N 3.12Å; A40-R42 VanDerWaalsContact C-N 3.31Å; A40-R42 PolarHBondContact O-N 3.08Å
41N90.7Very high91.8Very high115 Ų115103.1 Ų103.162%0.61554%0.535SS*.THydrogen-bonded Turntrans67.418.4-176.4-50.3-70.1000115.6S35 K36 F39S35-N41 WeakPolarHBondContact O-CA 3.48Å; S35-N41 PolarHBondContact O-N 3.46Å; S35-N41 WeakPolarHBondContact OG-CA 3.18Å; K36-N41 WeakPolarHBondContact CG-OD1 3.26Å; F39-N41 VanDerWaalsContact C-N 3.26Å; F39-N41 PolarHBondContact O-N 2.93Å
42R88.8Confident91.6Very high152 Ų152108.5 Ų108.557%0.57456%0.557SS**  trans-70.8146.3169.8-67170.3-178.3145.2-1110.6S35 F39 A40 V44S35-R42 VanDerWaalsContact CB-O 3.29Å; S35-R42 WeakPolarHBondContact CB-O 3.4Å; S35-R42 PolarHBondContact OG-O 3.41Å; F39-R42 HydrophobicContact CB-CB 4.17Å; F39-R42 VanDerWaalsContact O-CB 3.26Å; F39-R42 WeakPolarHBondContact O-CB 3.46Å; F39-R42 WeakPolarHBondContact O-CD 3.47Å; F39-R42 WeakPolarHBondContact O-CG 3.35Å; F39-R42 PolarHBondContact O-N 3.2Å; A40-R42 VanDerWaalsContact C-N 3.31Å; A40-R42 PolarHBondContact O-N 3.08Å; R42-V44 PolarHBondContact O-N 2.81Å
43S91.4Very high91.4Very high123 Ų123113.5 Ų113.586%0.8657%0.573SS**  trans-62.3133.1174.2-170.20000110.1
44V92.4Very high91.1Very high37 Ų37113.3 Ų113.322%0.22458%0.575CS.*  trans-132.8151.4176.4-64.10000109.2L31 F34 F39 R42L31-V44 HydrophobicContact CB-CG2 4.42Å; L31-V44 HydrophobicContact CD2-CG2 4Å; L31-V44 WeakPolarHBondContact O-CG2 3.44Å; F34-V44 HydrophobicContact CB-CG2 4.06Å; F39-V44 HydrophobicContact CB-CG1 4.13Å; F39-V44 HydrophobicContact CD1-CG1 4.49Å; F39-V44 HydrophobicContact CD2-CG1 3.63Å; F39-V44 HydrophobicContact CE2-CG1 4.13Å; F39-V44 HydrophobicContact CG-CG1 3.83Å; R42-V44 PolarHBondContact O-N 2.81Å
45S94Very high90.6Very high100 Ų100113.3 Ų113.370%0.69959%0.587SS**  trans-141.7152.8178.256.20000110
46F93.2Very high90Very high105 Ų105120.3 Ų120.346%0.46162%0.623SS.*  trans-77.7157.7164.1-65.6-62000110.2D27 L30 L31 F34D27-F46 HydrophobicContact CB-CD2 4.37Å; D27-F46 HydrophobicContact CB-CE2 4.04Å; L30-F46 HydrophobicContact CD2-CE2 4.42Å; L30-F46 HydrophobicContact CD2-CZ 3.74Å; L30-F46 HydrophobicContact CG-CZ 4.1Å; L31-F46 HydrophobicContact CD1-CD2 3.97Å; L31-F46 HydrophobicContact CD1-CE2 4.19Å; L31-F46 HydrophobicContact CD2-CD1 4.41Å; L31-F46 HydrophobicContact CD2-CD2 3.68Å; L31-F46 HydrophobicContact CD2-CE1 4.36Å; L31-F46 HydrophobicContact CD2-CE2 3.62Å; L31-F46 HydrophobicContact CD2-CG 4.08Å; L31-F46 HydrophobicContact CD2-CZ 3.97Å; L31-F46 HydrophobicContact CG-CD2 3.79Å; L31-F46 HydrophobicContact CG-CE2 3.56Å; L31-F46 HydrophobicContact CG-CZ 4.26Å; F34-F46 HydrophobicContact CD2-CE1 4.39Å; F34-F46 HydrophobicContact CD2-CZ 4.18Å; F34-F46 AromaticContact CE2-CE1 3.82Å; F34-F46 HydrophobicContact CE2-CE1 3.82Å; F34-F46 AromaticContact CE2-CZ 3.71Å; F34-F46 HydrophobicContact CE2-CZ 3.71Å
47T92.5Very high89.6Confident108 Ų108118 Ų11866%0.66362%0.623SS**  trans-140.1144.1170-178.50000108.9E49T47-E49 PolarHBondContact OG1-N 3.32Å; T47-E49 VanDerWaalsContact OG1-N 3.12Å
48E94.3Very high89.1Confident201 Ų201118.6 Ų118.694%0.93963%0.627SS**SBendtrans-94.4-11171.2-63.1-179.4-175.500111.5
49E94.7Very high89.2Confident149 Ų149121.1 Ų121.170%0.69664%0.64SS**SBendtrans-87.3121.1178.5-62.7-173.8172.400110.6T47 E51T47-E49 PolarHBondContact OG1-N 3.32Å; T47-E49 VanDerWaalsContact OG1-N 3.12Å; E49-E51 PolarHBondContact O-N 3.36Å; E49-E51 VanDerWaalsContact O-N 3.08Å
50M92.9Very high89.4Confident178 Ų178120.5 Ų120.588%0.87765%0.645SS**  trans-77.590.6171.9-175.9-179.3-67.500109.6F52M50-F52 HydrophobicContact CG-CE2 4.38Å
51E90.8Very high89.9Confident116 Ų116118.6 Ų118.654%0.54262%0.623SS.*  trans-118122.5178.5-164.4-15815400110.9E49 K53E49-E51 PolarHBondContact O-N 3.36Å; E49-E51 VanDerWaalsContact O-N 3.08Å; E51-K53 IonicContact OE1-NZ 2.75Å; E51-K53 PolarHBondContact OE1-NZ 3.32Å; E51-K53 IonicContact OE2-NZ 3.46Å; E51-K53 PolarHBondContact OE2-NZ 2.75Å
52F90.2Very high90.2Very high155 Ų155118.1 Ų118.168%0.6863%0.626SS**  trans-83.9129.4170.6-74.2-96.8000110M50 N54M50-F52 HydrophobicContact CG-CE2 4.38Å; F52-N54 PolarHBondContact O-N 2.74Å
53K87.8Confident90.6Very high153 Ų153115.3 Ų115.367%0.66562%0.622SS**  trans-80.6107.1171.7-61.1-61.4171.8-1660109.4E51E51-K53 IonicContact OE1-NZ 2.75Å; E51-K53 PolarHBondContact OE1-NZ 3.32Å; E51-K53 IonicContact OE2-NZ 3.46Å; E51-K53 PolarHBondContact OE2-NZ 2.75Å
54N85.4Confident90.9Very high95 Ų95113 Ų11351%0.50860%0.597SS.*  trans-99.3146.6179.9-67-39.6000110.8F52 D56 S57 T58F52-N54 PolarHBondContact O-N 2.74Å; N54-D56 PolarHBondContact O-N 3.28Å; N54-S57 PolarHBondContact O-N 2.99Å; N54-S57 VanDerWaalsContact O-N 3.11Å; N54-S57 PolarHBondContact O-OG 3.34Å; N54-T58 PolarHBondContact O-OG1 3.01Å; N54-T58 VanDerWaalsContact O-OG1 3.09Å
55A82.3Confident91Very high62 Ų62116.8 Ų116.851%0.51261%0.607SS.*G310 helixtrans-55.6-41.1178.200000111.7S57 T58A55-S57 PolarHBondContact O-N 3.25Å; A55-S57 VanDerWaalsContact O-N 3.16Å; A55-T58 PolarHBondContact O-N 2.87Å
56D80.6Confident90.9Very high167 Ų167112.7 Ų112.789%0.89358%0.578SS**G310 helixtrans-63.6-22.7-178.6-57.8-28.2000114.1N54N54-D56 PolarHBondContact O-N 3.28Å
57S82.2Confident90.9Very high83 Ų83107.7 Ų107.758%0.5856%0.556SS**G310 helixtrans-92.7-8.1178.762.90000113.7N54 A55N54-S57 PolarHBondContact O-N 2.99Å; N54-S57 VanDerWaalsContact O-N 3.11Å; N54-S57 PolarHBondContact O-OG 3.34Å; A55-S57 PolarHBondContact O-N 3.25Å; A55-S57 VanDerWaalsContact O-N 3.16Å
58T82.9Confident90.9Very high87 Ų87104.2 Ų104.253%0.53453%0.533SS..SBendtrans-95129.7-174.5-52.40000109.7N54 A55 T60N54-T58 PolarHBondContact O-OG1 3.01Å; N54-T58 VanDerWaalsContact O-OG1 3.09Å; A55-T58 PolarHBondContact O-N 2.87Å; T58-T60 PolarHBondContact O-N 2.6Å
59E91.3Very high90.7Very high181 Ų18197.4 Ų97.485%0.84651%0.508SS*.PPolyproline II helixtrans-59.9133.4173.5-171.9177.3-173.500110.3
60T93.2Very high90.6Very high86 Ų8693.2 Ų93.253%0.52850%0.495SS..PPolyproline II helixtrans-77.7152.7-178.455.90000111.6T58 D267T58-T60 PolarHBondContact O-N 2.6Å; T60-D267 VanDerWaalsContact CA-OD2 3.3Å; T60-D267 WeakPolarHBondContact CA-OD2 3.42Å; T60-D267 WeakPolarHBondContact CB-OD1 3.47Å; T60-D267 HydrophobicContact CG2-CB 4.3Å
61I96.5Very high90.5Very high37 Ų3784.9 Ų84.919%0.1945%0.454CS..PPolyproline II helixtrans-65.5124176.6-62.8173.2000109D267 A270 T280 R282I61-D267 PolarHBondContact N-OD2 3.2Å; I61-A270 HydrophobicContact CD1-CB 3.69Å; I61-A270 WeakPolarHBondContact CD1-O 3.36Å; I61-T280 HydrophobicContact CD1-CG2 4.27Å; I61-R282 HydrophobicContact CB-CB 4.48Å; I61-R282 HydrophobicContact CG2-CB 3.77Å; I61-R282 PolarHBondContact O-NH1 2.96Å
62P97.6Very high90.5Very high105 Ų10585.9 Ų85.968%0.68245%0.454SS*.PPolyproline II helixtrans-69.4153.6-177.128.7-35.8000112F64P62-F64 PolarHBondContact O-N 3.37Å
63I97.5Very high90.5Very high94 Ų9480.5 Ų80.548%0.48243%0.432SS..EExtended strand (participates in β ladder)trans-88.9107.7179.3-56.2177.3000109.5R282 D284 M313I63-R282 HydrophobicContact CG1-CG 3.99Å; I63-D284 HydrophobicContact CG2-CB 3.9Å; I63-M313 HydrophobicContact CD1-CG 4.06Å; I63-M313 HydrophobicContact CG1-CG 4.25Å
64F96.5Very high90.6Very high75 Ų7577.6 Ų77.633%0.32942%0.423SS..EExtended strand (participates in β ladder)trans-66.4135175.5178.2-107.6000111.5P62 V66 I281 R282 V283 D284 A290 C294P62-F64 PolarHBondContact O-N 3.37Å; F64-V66 HydrophobicContact CE1-CG2 3.74Å; F64-V66 HydrophobicContact CZ-CG2 3.7Å; F64-I281 HydrophobicContact CB-CD1 4.04Å; F64-I281 HydrophobicContact CB-CG1 4.36Å; F64-I281 HydrophobicContact CG-CD1 4.3Å; F64-R282 WeakPolarHBondContact CB-O 3.36Å; F64-R282 PolarHBondContact N-O 3.32Å; F64-V283 HydrophobicContact CB-CG2 4.45Å; F64-V283 HydrophobicContact CD1-CG2 4.03Å; F64-V283 WeakPolarHBondContact O-CG2 3.4Å; F64-D284 PolarHBondContact O-N 3Å; F64-A290 HydrophobicContact CD1-CB 3.79Å; F64-A290 HydrophobicContact CE1-CB 3.84Å; F64-C294 WeakPolarHBondContact CD1-SG 3.43Å
65R93.8Very high90.3Very high116 Ų11676.3 Ų76.344%0.43842%0.416SS..  trans-148.9143-179.3-172.2173.464-177.6-6.1110.8M67 L74 D284 D287R65-M67 WeakPolarHBondContact CD-O 3.38Å; R65-M67 WeakPolarHBondContact CG-O 3.02Å; R65-L74 HydrophobicContact CG-CD1 4.32Å; R65-D284 HydrophobicContact CB-CB 4.17Å; R65-D284 WeakPolarHBondContact CD-OD2 3.21Å; R65-D284 HydrophobicContact CG-CB 4.16Å; R65-D287 HydrophobicContact CG-CB 4.27Å; R65-D287 VanDerWaalsContact CG-OD2 3.28Å; R65-D287 WeakPolarHBondContact CG-OD2 3.39Å
66V93.7Very high89.4Confident14 Ų1481.8 Ų81.89%0.08543%0.428CS..SBendtrans-107.2-38.8-179.2171.60000111.1F64 L73 L74 T79 D287 F289 A290F64-V66 HydrophobicContact CE1-CG2 3.74Å; F64-V66 HydrophobicContact CZ-CG2 3.7Å; V66-L73 HydrophobicContact CG1-CD2 4.2Å; V66-L74 PolarHBondContact O-N 3Å; V66-T79 HydrophobicContact CG1-CG2 3.35Å; V66-D287 WeakPolarHBondContact CA-OD2 3.46Å; V66-D287 PolarHBondContact N-OD2 3.26Å; V66-F289 HydrophobicContact CB-CB 4.15Å; V66-F289 HydrophobicContact CG1-CB 3.86Å; V66-A290 HydrophobicContact CB-CB 4.26Å; V66-A290 HydrophobicContact CG2-CB 3.85Å
67M92.2Very high88.3Confident0 Ų082.7 Ų82.70%043%0.43CS..BIsolated β-bridgetrans-126135.3-174.7178.9173.262.400110.7R65 G71 Y72 L73 D287 F289 R347 F351R65-M67 WeakPolarHBondContact CD-O 3.38Å; R65-M67 WeakPolarHBondContact CG-O 3.02Å; M67-G71 VanDerWaalsContact SD-CA 3.54Å; M67-Y72 CarbonylContact C-O 3.45Å; M67-Y72 WeakPolarHBondContact CA-O 3.45Å; M67-L73 HydrophobicContact CB-CD2 4.21Å; M67-D287 PolarHBondContact N-OD2 3.07Å; M67-F289 HydrophobicContact CB-CD2 4.44Å; M67-F289 HydrophobicContact CE-CD2 4.11Å; M67-F289 HydrophobicContact CE-CE2 4.19Å; M67-F289 HydrophobicContact SD-CD2 4.14Å; M67-F289 HydrophobicContact SD-CE2 4.01Å; M67-R347 HydrophobicContact CE-CB 4.38Å; M67-R347 HydrophobicContact CE-CG 3.89Å; M67-R347 PolarHBondContact O-NH1 3.09Å; M67-R347 PolarHBondContact O-NH2 3.25Å; M67-F351 HydrophobicContact SD-CB 3.6Å; M67-F351 VanDerWaalsContact SD-CB 3.6Å; M67-F351 HydrophobicContact SD-CD2 4.13Å; M67-F351 HydrophobicContact SD-CG 4.02Å
68N92.6Very high87Confident35 Ų3586 Ų8619%0.18744%0.436CS..  trans-75.9172176.172.115.7000112.8S70 G71 Y72 L74 R347N68-S70 PolarHBondContact O-N 3.06Å; N68-S70 VanDerWaalsContact O-N 3.13Å; N68-S70 WeakPolarHBondContact OD1-CA 3.39Å; N68-S70 PolarHBondContact OD1-N 2.75Å; N68-S70 VanDerWaalsContact OD1-N 3.1Å; N68-G71 PolarHBondContact O-N 3.11Å; N68-G71 PolarHBondContact OD1-N 3.16Å; N68-Y72 PolarHBondContact N-O 3.16Å; N68-Y72 PolarHBondContact OD1-N 3.28Å; N68-L74 HydrophobicContact CB-CD1 4.43Å; N68-L74 HydrophobicContact CB-CD2 3.91Å; N68-L74 HydrophobicContact CB-CG 4.22Å; N68-R347 WeakPolarHBondContact O-CD 3.37Å; N68-R347 WeakPolarHBondContact O-CG 3.5Å
69S90.8Very high85.7Confident58 Ų5883.3 Ų83.341%0.40642%0.419SS..THydrogen-bonded Turntrans-59-24179.950.70000114G71S69-G71 VanDerWaalsContact C-N 3.33Å
70S91.2Very high84.2Confident61 Ų6177.9 Ų77.943%0.42740%0.395SS..THydrogen-bonded Turntrans-86.10.5175.3-51.70000113.6N68 S350 K354N68-S70 PolarHBondContact O-N 3.06Å; N68-S70 VanDerWaalsContact O-N 3.13Å; N68-S70 WeakPolarHBondContact OD1-CA 3.39Å; N68-S70 PolarHBondContact OD1-N 2.75Å; N68-S70 VanDerWaalsContact OD1-N 3.1Å; S70-S350 WeakPolarHBondContact O-CB 3.42Å; S70-K354 PolarHBondContact O-NZ 2.99Å
71G90.8Very high83Confident2 Ų281.3 Ų81.32%0.02141%0.411CS..SBendtrans83.119-179.800000115M67 N68 S69M67-G71 VanDerWaalsContact SD-CA 3.54Å; N68-G71 PolarHBondContact O-N 3.11Å; N68-G71 PolarHBondContact OD1-N 3.16Å; S69-G71 VanDerWaalsContact C-N 3.33Å
72Y91.3Very high81.9Confident137 Ų13781.1 Ų81.154%0.53741%0.41SS..  trans-95.2136172.8-64.2-74.5000111.2M67 N68 L74 K354M67-Y72 CarbonylContact C-O 3.45Å; M67-Y72 WeakPolarHBondContact CA-O 3.45Å; N68-Y72 PolarHBondContact N-O 3.16Å; N68-Y72 PolarHBondContact OD1-N 3.28Å; Y72-L74 PolarHBondContact O-N 3.41Å; Y72-K354 HydrophobicContact CD1-CD 4.21Å; Y72-K354 HydrophobicContact CE1-CD 3.82Å; Y72-K354 PolarHBondContact OH-NZ 3.29Å
73L91.3Very high81.3Confident43 Ų4380.1 Ų80.123%0.22540%0.399CS..BIsolated β-bridgetrans-69126.5172-57.4179000110.3V66 M67 T79 I82 F289 F351V66-L73 HydrophobicContact CG1-CD2 4.2Å; M67-L73 HydrophobicContact CB-CD2 4.21Å; L73-T79 HydrophobicContact CB-CG2 4.24Å; L73-T79 HydrophobicContact CD1-CG2 4.14Å; L73-T79 HydrophobicContact CD2-CG2 4.08Å; L73-T79 HydrophobicContact CG-CG2 4.37Å; L73-I82 HydrophobicContact CD1-CD1 3.95Å; L73-I82 HydrophobicContact CD2-CD1 3.7Å; L73-I82 HydrophobicContact CG-CD1 4.48Å; L73-F289 HydrophobicContact CD2-CD2 4.16Å; L73-F289 HydrophobicContact CD2-CE2 4.45Å; L73-F351 HydrophobicContact CD1-CE2 4.03Å; L73-F351 HydrophobicContact CD2-CD2 4.36Å; L73-F351 HydrophobicContact CD2-CE2 4.05Å; L73-F351 HydrophobicContact CG-CD2 4.46Å; L73-F351 HydrophobicContact CG-CE2 4.01Å
74L88.5Confident81Confident91 Ų9176.5 Ų76.548%0.47638%0.384SS..SBendtrans-81.2-41.7-172.8-71.4173.8000113R65 V66 N68 Y72R65-L74 HydrophobicContact CG-CD1 4.32Å; V66-L74 PolarHBondContact O-N 3Å; N68-L74 HydrophobicContact CB-CD1 4.43Å; N68-L74 HydrophobicContact CB-CD2 3.91Å; N68-L74 HydrophobicContact CB-CG 4.22Å; Y72-L74 PolarHBondContact O-N 3.41Å
75N79.2Confident81Confident68 Ų6880 Ų8036%0.36440%0.402SS..  trans-124.391.8179.8-171.7-13.1000110.1M77 Q78 T79N75-M77 PolarHBondContact O-N 3.24Å; N75-M77 VanDerWaalsContact O-N 3.15Å; N75-M77 PolarHBondContact OD1-N 2.96Å; N75-M77 VanDerWaalsContact OD1-N 3.12Å; N75-Q78 HydrophobicContact CB-CB 4.38Å; N75-Q78 WeakPolarHBondContact ND2-CG 3.42Å; N75-Q78 PolarHBondContact ND2-OE1 3.26Å; N75-Q78 PolarHBondContact O-N 3.47Å; N75-Q78 PolarHBondContact OD1-N 3.39Å; N75-T79 PolarHBondContact O-N 2.98Å; N75-T79 VanDerWaalsContact O-N 3.08Å; N75-T79 PolarHBondContact O-OG1 3.34Å
76K64.7Low81.1Confident177 Ų17776.2 Ų76.277%0.7739%0.39SS*.THydrogen-bonded Turntrans-60.4-20.3179.4-69.9-167.4179-171.80114T79K76-T79 VanDerWaalsContact C-OG1 3.29Å; K76-T79 WeakPolarHBondContact CA-OG1 3.49Å; K76-T79 PolarHBondContact O-OG1 3.13Å
77M56.4Low81.2Confident186 Ų18675.6 Ų75.692%0.91639%0.386SS*.THydrogen-bonded Turntrans-88.4-23-179.2-62.3-140.5-57.600113.8N75N75-M77 PolarHBondContact O-N 3.24Å; N75-M77 VanDerWaalsContact O-N 3.15Å; N75-M77 PolarHBondContact OD1-N 2.96Å; N75-M77 VanDerWaalsContact OD1-N 3.12Å
78Q54.3Low81.4Confident152 Ų15277.2 Ų77.271%0.7139%0.394SS*.THydrogen-bonded Turntrans-104-5.7176.3-73.9179.7-11.900113N75 I80N75-Q78 HydrophobicContact CB-CB 4.38Å; N75-Q78 WeakPolarHBondContact ND2-CG 3.42Å; N75-Q78 PolarHBondContact ND2-OE1 3.26Å; N75-Q78 PolarHBondContact O-N 3.47Å; N75-Q78 PolarHBondContact OD1-N 3.39Å; Q78-I80 PolarHBondContact O-N 2.92Å
79T55.8Low81.7Confident31 Ų3181.2 Ų81.219%0.1941%0.407CS..SBendtrans-71.2125.6179.411.60000109V66 L73 N75 K76 N81V66-T79 HydrophobicContact CG1-CG2 3.35Å; L73-T79 HydrophobicContact CB-CG2 4.24Å; L73-T79 HydrophobicContact CD1-CG2 4.14Å; L73-T79 HydrophobicContact CD2-CG2 4.08Å; L73-T79 HydrophobicContact CG-CG2 4.37Å; N75-T79 PolarHBondContact O-N 2.98Å; N75-T79 VanDerWaalsContact O-N 3.08Å; N75-T79 PolarHBondContact O-OG1 3.34Å; K76-T79 VanDerWaalsContact C-OG1 3.29Å; K76-T79 WeakPolarHBondContact CA-OG1 3.49Å; K76-T79 PolarHBondContact O-OG1 3.13Å; T79-N81 PolarHBondContact O-N 3.48Å
80I60.4Low82Confident67 Ų6778.4 Ų78.434%0.34439%0.387SS..  trans-44.1138.6162-61.7-176.5000107.5Q78 I82 Y292 S293Q78-I80 PolarHBondContact O-N 2.92Å; I80-I82 WeakPolarHBondContact O-CG1 3.47Å; I80-I82 PolarHBondContact O-N 3.34Å; I80-Y292 HydrophobicContact CD1-CD1 4.05Å; I80-Y292 HydrophobicContact CD1-CE1 4.14Å; I80-S293 WeakPolarHBondContact CD1-OG 3.21Å
81N67.8Low82.4Confident159 Ų15975.6 Ų75.685%0.8537%0.367SS*.  trans-6293.4169-171.415.2000107.2T79 D83T79-N81 PolarHBondContact O-N 3.48Å; N81-D83 PolarHBondContact O-N 3.36Å
82I72.9Confident82.7Confident33 Ų3379.1 Ų79.117%0.16938%0.382CS..  trans-67.4105.9-174.8-68.7159.4000106.4L73 I80 G84 A87 F289 F351L73-I82 HydrophobicContact CD1-CD1 3.95Å; L73-I82 HydrophobicContact CD2-CD1 3.7Å; L73-I82 HydrophobicContact CG-CD1 4.48Å; I80-I82 WeakPolarHBondContact O-CG1 3.47Å; I80-I82 PolarHBondContact O-N 3.34Å; I82-G84 PolarHBondContact O-N 3.3Å; I82-A87 HydrophobicContact CG2-CB 3.95Å; I82-F289 HydrophobicContact CB-CE1 4.48Å; I82-F289 HydrophobicContact CD1-CD1 3.99Å; I82-F289 HydrophobicContact CD1-CD2 3.56Å; I82-F289 HydrophobicContact CD1-CE1 4.06Å; I82-F289 HydrophobicContact CD1-CE2 3.62Å; I82-F289 HydrophobicContact CD1-CG 3.77Å; I82-F289 HydrophobicContact CD1-CZ 3.89Å; I82-F289 HydrophobicContact CG1-CD1 4.05Å; I82-F289 HydrophobicContact CG1-CD2 4.49Å; I82-F289 HydrophobicContact CG1-CE1 4.11Å; I82-F289 HydrophobicContact CG1-CG 4.27Å; I82-F289 HydrophobicContact CG1-CZ 4.36Å; I82-F289 HydrophobicContact CG2-CD1 4.23Å; I82-F289 HydrophobicContact CG2-CE1 3.49Å; I82-F289 VanDerWaalsContact CG2-CE1 3.49Å; I82-F289 HydrophobicContact CG2-CE2 4.46Å; I82-F289 HydrophobicContact CG2-CZ 3.63Å; I82-F351 HydrophobicContact CD1-CE2 4.46Å; I82-F351 HydrophobicContact CD1-CZ 4.15Å; I82-F351 HydrophobicContact CG2-CE1 4.24Å; I82-F351 HydrophobicContact CG2-CZ 4.17Å
83D85.8Confident83.1Confident83 Ų8373.6 Ų73.644%0.44436%0.362SS..  trans-60.4119.7170.6170.926000109.3N81 H85 L86 A87N81-D83 PolarHBondContact O-N 3.36Å; D83-H85 PolarHBondContact O-N 2.92Å; D83-H85 IonicContact OD1-CD2 3.56Å; D83-H85 IonicContact OD1-CG 2.81Å; D83-H85 PolarHBondContact OD1-N 3.33Å; D83-L86 HydrophobicContact CB-CB 3.94Å; D83-L86 WeakPolarHBondContact O-CB 3.26Å; D83-L86 PolarHBondContact O-N 2.95Å; D83-L86 VanDerWaalsContact O-N 3.11Å; D83-L86 PolarHBondContact OD2-N 2.62Å; D83-A87 PolarHBondContact O-N 2.9Å
84G92Very high83.4Confident18 Ų1871.6 Ų71.619%0.18635%0.351CS..Hα-helixtrans-58.6-33.7179.500000112.2I82 A87 I88I82-G84 PolarHBondContact O-N 3.3Å; G84-A87 PolarHBondContact O-N 3.5Å; G84-I88 WeakPolarHBondContact O-CB 3.48Å; G84-I88 WeakPolarHBondContact O-CD1 3.29Å; G84-I88 WeakPolarHBondContact O-CG1 3.41Å; G84-I88 PolarHBondContact O-N 3.4Å
85H95.3Very high83.8Confident150 Ų15067.5 Ų67.569%0.69433%0.33SS*.Hα-helixtrans-66.9-42.7176-68.8-68.7000111.8D83 I88 R89D83-H85 PolarHBondContact O-N 2.92Å; D83-H85 IonicContact OD1-CD2 3.56Å; D83-H85 IonicContact OD1-CG 2.81Å; D83-H85 PolarHBondContact OD1-N 3.33Å; H85-I88 PolarHBondContact O-N 2.97Å; H85-R89 WeakPolarHBondContact O-CB 3.15Å; H85-R89 PolarHBondContact O-N 3.21Å
86L95.4Very high84.8Confident36 Ų3665.7 Ų65.719%0.18832%0.319CS..Hα-helixtrans-60.3-47.3174.2-175.769.6000111.5D83 I88 R89 M90 W151 Y292D83-L86 HydrophobicContact CB-CB 3.94Å; D83-L86 WeakPolarHBondContact O-CB 3.26Å; D83-L86 PolarHBondContact O-N 2.95Å; D83-L86 VanDerWaalsContact O-N 3.11Å; D83-L86 PolarHBondContact OD2-N 2.62Å; L86-I88 PolarHBondContact O-N 2.88Å; L86-R89 PolarHBondContact O-N 2.96Å; L86-M90 HydrophobicContact CD1-CE 4.14Å; L86-M90 HydrophobicContact CD2-CE 3.94Å; L86-M90 HydrophobicContact CG-CE 3.82Å; L86-M90 HydrophobicContact CG-SD 4.37Å; L86-M90 WeakPolarHBondContact O-CG 3.39Å; L86-M90 PolarHBondContact O-N 3.19Å; L86-W151 HydrophobicContact CD1-CH2 3.63Å; L86-W151 HydrophobicContact CD1-CZ2 3.93Å; L86-Y292 HydrophobicContact CD2-CD2 4.41Å; L86-Y292 HydrophobicContact CD2-CE1 4.36Å; L86-Y292 HydrophobicContact CD2-CE2 3.82Å
87A96.3Very high86.4Confident0 Ų057.3 Ų57.30%028%0.282CS..Hα-helixtrans-62.1-43.5179.200000112.3I82 D83 G84 M90 F91 F289 F351 L352I82-A87 HydrophobicContact CG2-CB 3.95Å; D83-A87 PolarHBondContact O-N 2.9Å; G84-A87 PolarHBondContact O-N 3.5Å; A87-M90 PolarHBondContact O-N 2.86Å; A87-F91 WeakPolarHBondContact O-CB 3.22Å; A87-F91 PolarHBondContact O-N 3.49Å; A87-F289 HydrophobicContact CB-CE1 4.11Å; A87-F289 HydrophobicContact CB-CZ 4.07Å; A87-F351 HydrophobicContact CB-CE1 4.32Å; A87-L352 HydrophobicContact CB-CD2 3.92Å
88I97.5Very high88.3Confident34 Ų3452 Ų5217%0.17426%0.256CS..Hα-helixtrans-62.1-45.4174.3-68163.7000110.2G84 H85 L86 M90 F91 K92 L352 L357 F358G84-I88 WeakPolarHBondContact O-CB 3.48Å; G84-I88 WeakPolarHBondContact O-CD1 3.29Å; G84-I88 WeakPolarHBondContact O-CG1 3.41Å; G84-I88 PolarHBondContact O-N 3.4Å; H85-I88 PolarHBondContact O-N 2.97Å; L86-I88 PolarHBondContact O-N 2.88Å; I88-M90 VanDerWaalsContact C-N 3.34Å; I88-M90 PolarHBondContact O-N 2.81Å; I88-F91 PolarHBondContact O-N 3Å; I88-K92 HydrophobicContact CG2-CD 4.06Å; I88-K92 HydrophobicContact CG2-CG 4.19Å; I88-K92 WeakPolarHBondContact O-CB 3.23Å; I88-K92 VanDerWaalsContact O-CG 3.28Å; I88-K92 WeakPolarHBondContact O-CG 3.33Å; I88-K92 PolarHBondContact O-N 3.39Å; I88-L352 HydrophobicContact CG1-CD2 4.26Å; I88-L357 HydrophobicContact CD1-CB 4.28Å; I88-L357 VanDerWaalsContact CD1-O 3.29Å; I88-L357 WeakPolarHBondContact CD1-O 3.3Å; I88-L357 HydrophobicContact CG1-CB 4.38Å; I88-F358 HydrophobicContact CG2-CD2 4.32Å; I88-F358 HydrophobicContact CG2-CE2 4.36Å
89R97.8Very high90.4Very high119 Ų11945.1 Ų45.145%0.44922%0.224SC..Hα-helixtrans-60.4-43.5178.8-177.1-178.4172.4-170.2-2111.7H85 L86 K92 N93 W151H85-R89 WeakPolarHBondContact O-CB 3.15Å; H85-R89 PolarHBondContact O-N 3.21Å; L86-R89 PolarHBondContact O-N 2.96Å; R89-K92 PolarHBondContact O-N 3.03Å; R89-N93 PolarHBondContact O-N 3.08Å; R89-N93 VanDerWaalsContact O-N 3.11Å; R89-N93 PolarHBondContact O-ND2 2.74Å; R89-W151 HydrophobicContact CB-CH2 4.41Å; R89-W151 HydrophobicContact CB-CZ3 4.36Å; R89-W151 HydrophobicContact CG-CE3 4.49Å; R89-W151 HydrophobicContact CG-CH2 3.97Å; R89-W151 HydrophobicContact CG-CZ3 3.74Å; R89-W151 PolarHBondContact NH2-O 3.24Å
90M98Very high92.4Very high0 Ų043.6 Ų43.60%022%0.215CC..Hα-helixtrans-58.7-49.5174.9-73.4172.5173.400111.1L86 A87 I88 K92 N93 M94 I127 A131 W151 I288 Y292 L348L86-M90 HydrophobicContact CD1-CE 4.14Å; L86-M90 HydrophobicContact CD2-CE 3.94Å; L86-M90 HydrophobicContact CG-CE 3.82Å; L86-M90 HydrophobicContact CG-SD 4.37Å; L86-M90 WeakPolarHBondContact O-CG 3.39Å; L86-M90 PolarHBondContact O-N 3.19Å; A87-M90 PolarHBondContact O-N 2.86Å; I88-M90 VanDerWaalsContact C-N 3.34Å; I88-M90 PolarHBondContact O-N 2.81Å; M90-K92 PolarHBondContact O-N 2.98Å; M90-N93 PolarHBondContact O-N 3.2Å; M90-M94 WeakPolarHBondContact O-CG 3.39Å; M90-M94 PolarHBondContact O-N 3.49Å; M90-I127 HydrophobicContact CB-CG2 4.07Å; M90-I127 HydrophobicContact CG-CG2 4.08Å; M90-A131 HydrophobicContact CE-CB 3.38Å; M90-W151 HydrophobicContact CB-CZ3 4.47Å; M90-W151 HydrophobicContact CG-CH2 3.99Å; M90-W151 HydrophobicContact CG-CZ3 3.76Å; M90-I288 HydrophobicContact CB-CD1 3.69Å; M90-I288 HydrophobicContact CG-CD1 4.02Å; M90-I288 HydrophobicContact SD-CD1 3.89Å; M90-I288 HydrophobicContact SD-CG1 3.99Å; M90-Y292 HydrophobicContact CE-CD2 3.46Å; M90-Y292 VanDerWaalsContact CE-CD2 3.46Å; M90-Y292 HydrophobicContact CE-CE2 4.11Å; M90-Y292 HydrophobicContact CE-CG 3.96Å; M90-L348 HydrophobicContact CB-CD2 4.24Å
91F98.2Very high94.2Very high1 Ų140.8 Ų40.80%0.00420%0.201CC..Hα-helixtrans-60.2-45.8179.4-172-120.3000112.7A87 I88 N93 M94 I95 L345 L348 R349 L352 F358 E363A87-F91 WeakPolarHBondContact O-CB 3.22Å; A87-F91 PolarHBondContact O-N 3.49Å; I88-F91 PolarHBondContact O-N 3Å; F91-N93 VanDerWaalsContact C-N 3.29Å; F91-N93 PolarHBondContact O-N 2.74Å; F91-M94 PolarHBondContact O-N 2.97Å; F91-M94 VanDerWaalsContact O-N 3.15Å; F91-I95 HydrophobicContact CD1-CD1 3.78Å; F91-I95 HydrophobicContact CE1-CD1 3.49Å; F91-I95 VanDerWaalsContact CE1-CD1 3.49Å; F91-I95 HydrophobicContact CE1-CG1 4.46Å; F91-I95 HydrophobicContact CE2-CD1 4.4Å; F91-I95 HydrophobicContact CG-CD1 4.36Å; F91-I95 HydrophobicContact CZ-CD1 3.83Å; F91-I95 HydrophobicContact CZ-CG1 4.41Å; F91-I95 WeakPolarHBondContact O-CG1 3.49Å; F91-I95 PolarHBondContact O-N 3.05Å; F91-L345 HydrophobicContact CD2-CD1 3.68Å; F91-L345 HydrophobicContact CE2-CD1 3.38Å; F91-L345 HydrophobicContact CE2-CG 4.07Å; F91-L345 HydrophobicContact CZ-CD1 4.27Å; F91-L348 HydrophobicContact CB-CD2 3.63Å; F91-L348 HydrophobicContact CB-CG 4.14Å; F91-L348 HydrophobicContact CD2-CB 4.17Å; F91-L348 HydrophobicContact CD2-CD2 3.91Å; F91-L348 HydrophobicContact CD2-CG 3.9Å; F91-L348 HydrophobicContact CG-CD2 4.25Å; F91-L348 HydrophobicContact CG-CG 4.39Å; F91-R349 HydrophobicContact CE2-CB 3.68Å; F91-R349 HydrophobicContact CE2-CG 4.44Å; F91-R349 HydrophobicContact CZ-CB 3.72Å; F91-R349 HydrophobicContact CZ-CG 3.98Å; F91-L352 HydrophobicContact CB-CD1 3.45Å; F91-L352 VanDerWaalsContact CB-CD1 3.45Å; F91-L352 HydrophobicContact CD1-CD1 3.49Å; F91-L352 VanDerWaalsContact CD1-CD1 3.49Å; F91-L352 HydrophobicContact CD2-CD1 4.03Å; F91-L352 HydrophobicContact CE1-CD1 4.19Å; F91-L352 HydrophobicContact CG-CD1 3.39Å; F91-F358 AromaticContact CD1-CD1 3.87Å; F91-F358 HydrophobicContact CD1-CD1 3.87Å; F91-F358 AromaticContact CD1-CE1 3.88Å; F91-F358 HydrophobicContact CD1-CE1 3.88Å; F91-F358 HydrophobicContact CD1-CG 4.38Å; F91-F358 HydrophobicContact CD1-CZ 4.45Å; F91-F358 AromaticContact CE1-CD1 3.5Å; F91-F358 HydrophobicContact CE1-CD1 3.5Å; F91-F358 AromaticContact CE1-CE1 3.55Å; F91-F358 HydrophobicContact CE1-CE1 3.55Å; F91-F358 HydrophobicContact CE1-CG 4.38Å; F91-F358 HydrophobicContact CE1-CZ 4.5Å; F91-E363 HydrophobicContact CE1-CG 4.32Å; F91-E363 HydrophobicContact CZ-CG 4.34Å
92K98.4Very high95.7Very high77 Ų7737 Ų3734%0.33518%0.178SC..Hα-helixtrans-57.5-40.9175.7-71.1-171.5173.3179.40112.1I88 R89 M90 F96 L366 Y370I88-K92 HydrophobicContact CG2-CD 4.06Å; I88-K92 HydrophobicContact CG2-CG 4.19Å; I88-K92 WeakPolarHBondContact O-CB 3.23Å; I88-K92 VanDerWaalsContact O-CG 3.28Å; I88-K92 WeakPolarHBondContact O-CG 3.33Å; I88-K92 PolarHBondContact O-N 3.39Å; R89-K92 PolarHBondContact O-N 3.03Å; M90-K92 PolarHBondContact O-N 2.98Å; K92-F96 WeakPolarHBondContact O-CB 3.27Å; K92-F96 PolarHBondContact O-N 3.42Å; K92-L366 HydrophobicContact CB-CD2 4.15Å; K92-L366 HydrophobicContact CD-CD2 4.27Å; K92-L366 HydrophobicContact CG-CD2 3.63Å; K92-Y370 WeakPolarHBondContact O-CE2 3.39Å
93N98.5Very high96.9Very high20 Ų2036.4 Ų36.411%0.10718%0.175CC..Hα-helixtrans-69.8-35.2177.8-82.7-89.9000112.6R89 M90 F91 F96 M97 I127 L150R89-N93 PolarHBondContact O-N 3.08Å; R89-N93 VanDerWaalsContact O-N 3.11Å; R89-N93 PolarHBondContact O-ND2 2.74Å; M90-N93 PolarHBondContact O-N 3.2Å; F91-N93 VanDerWaalsContact C-N 3.29Å; F91-N93 PolarHBondContact O-N 2.74Å; N93-F96 PolarHBondContact O-N 2.94Å; N93-M97 WeakPolarHBondContact O-CB 3.18Å; N93-M97 PolarHBondContact O-N 3.09Å; N93-I127 HydrophobicContact CB-CD1 3.67Å; N93-I127 HydrophobicContact CB-CG1 4.23Å; N93-I127 HydrophobicContact CB-CG2 4.29Å; N93-L150 PolarHBondContact OD1-O 2.94Å
94M98.2Very high97.5Very high1 Ų132.4 Ų32.41%0.00515%0.154CC..Hα-helixtrans-65.5-43.9175.2-64.2170.972.600111.7M90 F91 F96 M97 Q98 E123 A124 I127 I288 P344 L345 L348M90-M94 WeakPolarHBondContact O-CG 3.39Å; M90-M94 PolarHBondContact O-N 3.49Å; F91-M94 PolarHBondContact O-N 2.97Å; F91-M94 VanDerWaalsContact O-N 3.15Å; M94-F96 VanDerWaalsContact C-N 3.31Å; M94-F96 PolarHBondContact O-N 2.92Å; M94-M97 PolarHBondContact O-N 3.31Å; M94-Q98 PolarHBondContact O-N 3.25Å; M94-E123 HydrophobicContact CB-CB 4.26Å; M94-E123 HydrophobicContact CE-CB 3.82Å; M94-E123 HydrophobicContact CG-CB 3.98Å; M94-A124 HydrophobicContact CE-CB 4.33Å; M94-I127 HydrophobicContact CG-CB 4.45Å; M94-I127 HydrophobicContact CG-CG1 4.16Å; M94-I288 HydrophobicContact SD-CD1 3.69Å; M94-P344 HydrophobicContact CE-CB 3.69Å; M94-P344 HydrophobicContact CE-CG 4.15Å; M94-L345 HydrophobicContact CB-CD1 3.69Å; M94-L345 HydrophobicContact CE-CB 4.04Å; M94-L345 HydrophobicContact CE-CD1 4.35Å; M94-L348 HydrophobicContact SD-CD2 3.81Å
95I98.2Very high97.8Very high6 Ų633.9 Ų33.93%0.03115%0.154CC..Hα-helixtrans-61.1-43.9174.1-62.3167.9000110.2F91 M97 Q98 A99 L345 E363 L366 A367 Y370F91-I95 HydrophobicContact CD1-CD1 3.78Å; F91-I95 HydrophobicContact CE1-CD1 3.49Å; F91-I95 VanDerWaalsContact CE1-CD1 3.49Å; F91-I95 HydrophobicContact CE1-CG1 4.46Å; F91-I95 HydrophobicContact CE2-CD1 4.4Å; F91-I95 HydrophobicContact CG-CD1 4.36Å; F91-I95 HydrophobicContact CZ-CD1 3.83Å; F91-I95 HydrophobicContact CZ-CG1 4.41Å; F91-I95 WeakPolarHBondContact O-CG1 3.49Å; F91-I95 PolarHBondContact O-N 3.05Å; I95-M97 PolarHBondContact O-N 3.09Å; I95-Q98 PolarHBondContact O-N 3.35Å; I95-A99 PolarHBondContact O-N 3.27Å; I95-L345 HydrophobicContact CG1-CD1 3.85Å; I95-E363 HydrophobicContact CD1-CG 3.89Å; I95-L366 HydrophobicContact CD1-CD2 4.02Å; I95-A367 HydrophobicContact CG2-CB 3.96Å; I95-Y370 HydrophobicContact CB-CD2 4.49Å; I95-Y370 HydrophobicContact CB-CE2 4.49Å; I95-Y370 HydrophobicContact CG2-CD2 4.02Å; I95-Y370 HydrophobicContact CG2-CE2 4.43Å
96F98.5Very high97.9Very high30 Ų3030.1 Ų30.113%0.13214%0.139CC..Hα-helixtrans-61.8-44.4179.7-174-149.8000111.9K92 N93 M94 Q98 A99 I100 L150 L156 Y370 V374K92-F96 WeakPolarHBondContact O-CB 3.27Å; K92-F96 PolarHBondContact O-N 3.42Å; N93-F96 PolarHBondContact O-N 2.94Å; M94-F96 VanDerWaalsContact C-N 3.31Å; M94-F96 PolarHBondContact O-N 2.92Å; F96-Q98 VanDerWaalsContact C-N 3.34Å; F96-Q98 PolarHBondContact O-N 3.11Å; F96-A99 WeakPolarHBondContact O-CB 3.4Å; F96-A99 PolarHBondContact O-N 3.43Å; F96-I100 HydrophobicContact CD1-CD1 4.21Å; F96-I100 HydrophobicContact CD2-CD1 4.04Å; F96-I100 HydrophobicContact CD2-CG1 4.12Å; F96-I100 HydrophobicContact CE1-CD1 4.01Å; F96-I100 HydrophobicContact CE2-CD1 3.84Å; F96-I100 HydrophobicContact CE2-CG1 3.91Å; F96-I100 HydrophobicContact CG-CD1 4.23Å; F96-I100 HydrophobicContact CZ-CD1 3.83Å; F96-I100 HydrophobicContact CZ-CG1 4.35Å; F96-I100 WeakPolarHBondContact O-CG1 3.35Å; F96-I100 PolarHBondContact O-N 3.47Å; F96-L150 HydrophobicContact CD1-CD1 4.23Å; F96-L150 HydrophobicContact CD1-CD2 4.1Å; F96-L150 HydrophobicContact CE1-CD2 3.91Å; F96-L156 HydrophobicContact CE2-CD1 4.24Å; F96-L156 HydrophobicContact CE2-CD2 4.08Å; F96-L156 HydrophobicContact CZ-CB 4.05Å; F96-L156 HydrophobicContact CZ-CD1 3.92Å; F96-L156 HydrophobicContact CZ-CD2 3.93Å; F96-L156 HydrophobicContact CZ-CG 4.17Å; F96-Y370 HydrophobicContact CB-CD2 3.72Å; F96-Y370 HydrophobicContact CB-CE2 3.61Å; F96-Y370 HydrophobicContact CB-CG 4.24Å; F96-Y370 AromaticContact CD2-CD1 3.86Å; F96-Y370 HydrophobicContact CD2-CD1 3.86Å; F96-Y370 HydrophobicContact CD2-CD2 4.08Å; F96-Y370 HydrophobicContact CD2-CE1 4.35Å; F96-Y370 AromaticContact CD2-CG 3.71Å; F96-Y370 HydrophobicContact CD2-CG 3.71Å; F96-Y370 HydrophobicContact CE2-CD1 4.3Å; F96-Y370 HydrophobicContact CE2-CG 4.47Å; F96-Y370 HydrophobicContact CG-CD1 4.35Å; F96-Y370 HydrophobicContact CG-CD2 4.25Å; F96-Y370 HydrophobicContact CG-CE1 4.41Å; F96-Y370 HydrophobicContact CG-CE2 4.3Å; F96-Y370 HydrophobicContact CG-CG 4.27Å; F96-V374 HydrophobicContact CE2-CG2 4.07Å
97M98.2Very high98.1Very high0 Ų028.5 Ų28.50%013%0.131CC..Hα-helixtrans-60.7-42.6176.3-168.8157.267.300112.2N93 M94 I95 A99 I100 D101 N119 E123 I127 L146 L150N93-M97 WeakPolarHBondContact O-CB 3.18Å; N93-M97 PolarHBondContact O-N 3.09Å; M94-M97 PolarHBondContact O-N 3.31Å; I95-M97 PolarHBondContact O-N 3.09Å; M97-A99 VanDerWaalsContact C-N 3.33Å; M97-A99 PolarHBondContact O-N 3.39Å; M97-I100 PolarHBondContact O-N 3.46Å; M97-D101 WeakPolarHBondContact O-CB 3.3Å; M97-D101 PolarHBondContact O-N 3.35Å; M97-N119 HydrophobicContact CE-CB 3.98Å; M97-N119 HydrophobicContact CG-CB 4.23Å; M97-N119 HydrophobicContact SD-CB 3.92Å; M97-E123 HydrophobicContact CE-CB 3.28Å; M97-E123 HydrophobicContact CE-CG 3.28Å; M97-I127 HydrophobicContact CE-CG1 4.44Å; M97-L146 HydrophobicContact CG-CD2 4.01Å; M97-L146 HydrophobicContact CG-CG 4.32Å; M97-L146 HydrophobicContact SD-CB 3.99Å; M97-L146 HydrophobicContact SD-CD2 4.47Å; M97-L146 HydrophobicContact SD-CG 4.19Å; M97-L150 HydrophobicContact CB-CD1 3.67Å; M97-L150 HydrophobicContact CG-CD1 4.06Å; M97-L150 HydrophobicContact SD-CD1 4.3Å
98Q97.1Very high98.2Very high76 Ų7629.7 Ų29.736%0.35514%0.136SC..Hα-helixtrans-62.7-39.8175.7-169.5179.67.600111.9M94 I95 F96 D101 E102M94-Q98 PolarHBondContact O-N 3.25Å; I95-Q98 PolarHBondContact O-N 3.35Å; F96-Q98 VanDerWaalsContact C-N 3.34Å; F96-Q98 PolarHBondContact O-N 3.11Å; Q98-D101 PolarHBondContact O-N 3.41Å; Q98-E102 PolarHBondContact O-N 3.05Å
99A98.3Very high98.1Very high6 Ų634.3 Ų34.35%0.0515%0.151CC..Hα-helixtrans-65.3-4117600000112.3I95 F96 M97 I103 R371I95-A99 PolarHBondContact O-N 3.27Å; F96-A99 WeakPolarHBondContact O-CB 3.4Å; F96-A99 PolarHBondContact O-N 3.43Å; M97-A99 VanDerWaalsContact C-N 3.33Å; M97-A99 PolarHBondContact O-N 3.39Å; A99-I103 WeakPolarHBondContact O-CG1 3.31Å; A99-I103 PolarHBondContact O-N 3.42Å; A99-R371 HydrophobicContact CB-CG 4.21Å
100I98.7Very high98.1Very high0 Ų034.6 Ų34.60%016%0.158CC..Hα-helixtrans-60.7-50.2173.7-66.9164.9000109.9F96 M97 E102 I103 L104 L146 L150 L156 L159 V374F96-I100 HydrophobicContact CD1-CD1 4.21Å; F96-I100 HydrophobicContact CD2-CD1 4.04Å; F96-I100 HydrophobicContact CD2-CG1 4.12Å; F96-I100 HydrophobicContact CE1-CD1 4.01Å; F96-I100 HydrophobicContact CE2-CD1 3.84Å; F96-I100 HydrophobicContact CE2-CG1 3.91Å; F96-I100 HydrophobicContact CG-CD1 4.23Å; F96-I100 HydrophobicContact CZ-CD1 3.83Å; F96-I100 HydrophobicContact CZ-CG1 4.35Å; F96-I100 WeakPolarHBondContact O-CG1 3.35Å; F96-I100 PolarHBondContact O-N 3.47Å; M97-I100 PolarHBondContact O-N 3.46Å; I100-E102 PolarHBondContact O-N 3.43Å; I100-I103 PolarHBondContact O-N 3.03Å; I100-L104 HydrophobicContact CG2-CD1 3.65Å; I100-L104 HydrophobicContact CG2-CG 4.21Å; I100-L104 WeakPolarHBondContact O-CB 3.09Å; I100-L104 WeakPolarHBondContact O-CG 3.48Å; I100-L104 PolarHBondContact O-N 3.42Å; I100-L146 HydrophobicContact CB-CD2 4.5Å; I100-L146 HydrophobicContact CD1-CD2 4.4Å; I100-L146 HydrophobicContact CG2-CD2 4.02Å; I100-L150 HydrophobicContact CD1-CD1 4.04Å; I100-L150 HydrophobicContact CD1-CD2 3.7Å; I100-L156 HydrophobicContact CD1-CD1 4.04Å; I100-L156 HydrophobicContact CG1-CD1 3.95Å; I100-L159 HydrophobicContact CD1-CD1 4.11Å; I100-L159 HydrophobicContact CG2-CD1 4.38Å; I100-L159 HydrophobicContact CG2-CD2 4.16Å; I100-V374 HydrophobicContact CB-CG2 4.46Å; I100-V374 HydrophobicContact CG1-CG2 3.67Å
101D98.2Very high98Very high8 Ų837.6 Ų37.64%0.04319%0.189CC..Hα-helixtrans-60.7-45-176.6-80.9-14.1000112.5M97 Q98 Y105 Y116 T118 N119M97-D101 WeakPolarHBondContact O-CB 3.3Å; M97-D101 PolarHBondContact O-N 3.35Å; Q98-D101 PolarHBondContact O-N 3.41Å; D101-Y105 WeakPolarHBondContact O-CB 3.28Å; D101-Y105 PolarHBondContact O-N 3.04Å; D101-Y116 HydrophobicContact CB-CE1 4.39Å; D101-Y116 WeakPolarHBondContact OD1-CE1 3.49Å; D101-Y116 PolarHBondContact OD1-OH 2.8Å; D101-T118 HydrophobicContact CB-CG2 4.04Å; D101-N119 PolarHBondContact OD1-ND2 2.99Å; D101-N119 WeakPolarHBondContact OD2-CB 3.23Å; D101-N119 PolarHBondContact OD2-N 2.93Å; D101-N119 PolarHBondContact OD2-ND2 3.46Å; D101-N119 VanDerWaalsContact OD2-ND2 3.1Å
102E97.8Very high97.9Very high79 Ų7942.4 Ų42.437%0.36921%0.207SC..Hα-helixtrans-62.1-46.8179.2-170.6-169.8137.400111.9Q98 I100 N106 R371Q98-E102 PolarHBondContact O-N 3.05Å; I100-E102 PolarHBondContact O-N 3.43Å; E102-N106 WeakPolarHBondContact O-CB 3.42Å; E102-N106 VanDerWaalsContact O-CG 3.29Å; E102-N106 PolarHBondContact O-N 2.95Å; E102-N106 VanDerWaalsContact O-N 3.12Å; E102-N106 PolarHBondContact O-ND2 2.83Å; E102-R371 IonicContact OE1-CZ 2.79Å; E102-R371 VanDerWaalsContact OE1-CZ 3.25Å; E102-R371 IonicContact OE1-NH1 2.69Å; E102-R371 PolarHBondContact OE1-NH1 2.85Å; E102-R371 IonicContact OE1-NH2 3.42Å; E102-R371 PolarHBondContact OE1-NH2 2.96Å; E102-R371 IonicContact OE2-CZ 3.86Å; E102-R371 IonicContact OE2-NH1 2.75Å; E102-R371 PolarHBondContact OE2-NH1 3.14Å
103I98.5Very high97.9Very high20 Ų2039 Ų3910%0.10319%0.193CC..Hα-helixtrans-70.1-45.5-176.2-62.6-61.6000111.1A99 I100 N106 A107 V374 I375 L378A99-I103 WeakPolarHBondContact O-CG1 3.31Å; A99-I103 PolarHBondContact O-N 3.42Å; I100-I103 PolarHBondContact O-N 3.03Å; I103-N106 PolarHBondContact O-N 3.41Å; I103-A107 WeakPolarHBondContact O-CB 3.49Å; I103-A107 PolarHBondContact O-N 2.95Å; I103-V374 HydrophobicContact CB-CB 4.37Å; I103-V374 HydrophobicContact CB-CG1 3.69Å; I103-V374 HydrophobicContact CG1-CB 4.29Å; I103-V374 HydrophobicContact CG1-CG1 4.17Å; I103-V374 HydrophobicContact CG2-CB 4.44Å; I103-V374 HydrophobicContact CG2-CG1 3.68Å; I103-I375 HydrophobicContact CD1-CD1 4.02Å; I103-I375 HydrophobicContact CD1-CG1 3.85Å; I103-I375 HydrophobicContact CG1-CG1 4.31Å; I103-I375 HydrophobicContact CG2-CG1 4.2Å; I103-L378 HydrophobicContact CG2-CD2 4.22Å
104L98.6Very high97.9Very high0 Ų042.4 Ų42.40%022%0.218CC..Hα-helixtrans-73.5-34.5-178.5-65-174.4000112.5I100 N106 A107 Q108 I113 Y116 L159 V160 L378I100-L104 HydrophobicContact CG2-CD1 3.65Å; I100-L104 HydrophobicContact CG2-CG 4.21Å; I100-L104 WeakPolarHBondContact O-CB 3.09Å; I100-L104 WeakPolarHBondContact O-CG 3.48Å; I100-L104 PolarHBondContact O-N 3.42Å; L104-N106 PolarHBondContact O-N 3.29Å; L104-A107 PolarHBondContact O-N 3.29Å; L104-Q108 PolarHBondContact O-N 3.03Å; L104-I113 HydrophobicContact CB-CD1 4.23Å; L104-I113 WeakPolarHBondContact O-CD1 3.44Å; L104-Y116 HydrophobicContact CB-CD1 4.13Å; L104-Y116 HydrophobicContact CB-CD2 3.75Å; L104-Y116 HydrophobicContact CB-CE1 3.9Å; L104-Y116 HydrophobicContact CB-CE2 3.46Å; L104-Y116 VanDerWaalsContact CB-CE2 3.46Å; L104-Y116 HydrophobicContact CB-CG 4.08Å; L104-Y116 HydrophobicContact CD1-CD2 4.28Å; L104-Y116 HydrophobicContact CD1-CE2 3.43Å; L104-Y116 VanDerWaalsContact CD1-CE2 3.43Å; L104-Y116 HydrophobicContact CG-CE2 4.09Å; L104-L159 HydrophobicContact CD1-CD2 3.69Å; L104-V160 HydrophobicContact CD2-CG1 4.35Å; L104-V160 HydrophobicContact CD2-CG2 4.39Å; L104-L378 HydrophobicContact CD2-CD1 4.32Å
105Y98.3Very high97.9Very high49 Ų4943.9 Ų43.919%0.19222%0.224CC..Hα-helixtrans-59.7-46.8170.8-176-91.7000111.1D101 Q108 R109 T118 H319 T322D101-Y105 WeakPolarHBondContact O-CB 3.28Å; D101-Y105 PolarHBondContact O-N 3.04Å; Y105-Q108 WeakPolarHBondContact O-CB 3.29Å; Y105-Q108 PolarHBondContact O-N 3.06Å; Y105-R109 HydrophobicContact CD1-CG 4.24Å; Y105-R109 HydrophobicContact CE1-CG 3.95Å; Y105-R109 WeakPolarHBondContact O-CG 3.4Å; Y105-R109 PolarHBondContact O-N 3.46Å; Y105-T118 HydrophobicContact CD2-CG2 3.81Å; Y105-T118 HydrophobicContact CG-CG2 4.24Å; Y105-H319 PolarHBondContact OH-CD2 2.86Å; Y105-T322 HydrophobicContact CD2-CG2 3.61Å; Y105-T322 HydrophobicContact CE2-CG2 3.6Å; Y105-T322 HydrophobicContact CG-CG2 4.49Å
106N97.9Very high97.9Very high71 Ų7143.6 Ų43.638%0.3822%0.223SC..Hα-helixtrans-65.9-38.1176.1-74.9-32.7000112.7E102 I103 L104 Q108 R109 Q110E102-N106 WeakPolarHBondContact O-CB 3.42Å; E102-N106 VanDerWaalsContact O-CG 3.29Å; E102-N106 PolarHBondContact O-N 2.95Å; E102-N106 VanDerWaalsContact O-N 3.12Å; E102-N106 PolarHBondContact O-ND2 2.83Å; I103-N106 PolarHBondContact O-N 3.41Å; L104-N106 PolarHBondContact O-N 3.29Å; N106-Q108 VanDerWaalsContact C-N 3.26Å; N106-Q108 PolarHBondContact O-N 3.46Å; N106-R109 PolarHBondContact O-N 2.85Å; N106-Q110 WeakPolarHBondContact O-CG 3.44Å; N106-Q110 PolarHBondContact O-N 3.45Å; N106-Q110 VanDerWaalsContact O-N 3.1Å
107A98.1Very high97.9Very high2 Ų242.5 Ų42.52%0.01722%0.218CC..Hα-helixtrans-59.8-39.5173.700000111.4I103 L104 Q110 G111 R112 I113 L378I103-A107 WeakPolarHBondContact O-CB 3.49Å; I103-A107 PolarHBondContact O-N 2.95Å; L104-A107 PolarHBondContact O-N 3.29Å; A107-Q110 PolarHBondContact O-N 2.87Å; A107-G111 PolarHBondContact O-N 2.82Å; A107-R112 HydrophobicContact CB-CB 4.36Å; A107-R112 WeakPolarHBondContact O-CB 3.28Å; A107-R112 PolarHBondContact O-N 3.32Å; A107-I113 HydrophobicContact CB-CG1 4.45Å; A107-L378 HydrophobicContact CB-CD2 3.72Å
108Q98.4Very high97.8Very high24 Ų2443.4 Ų43.411%0.11222%0.224CC..Hα-helixtrans-65-43.5174.3-166.4-72.8-27.600111.4L104 Y105 N106 Q110 G111 I113 S114 T322L104-Q108 PolarHBondContact O-N 3.03Å; Y105-Q108 WeakPolarHBondContact O-CB 3.29Å; Y105-Q108 PolarHBondContact O-N 3.06Å; N106-Q108 VanDerWaalsContact C-N 3.26Å; N106-Q108 PolarHBondContact O-N 3.46Å; Q108-Q110 PolarHBondContact O-N 3.39Å; Q108-Q110 VanDerWaalsContact O-N 3.17Å; Q108-G111 WeakPolarHBondContact O-CA 3.3Å; Q108-G111 PolarHBondContact O-N 3.31Å; Q108-I113 HydrophobicContact CB-CD1 4.07Å; Q108-I113 HydrophobicContact CB-CG1 3.62Å; Q108-I113 HydrophobicContact CG-CG1 4.11Å; Q108-S114 PolarHBondContact NE2-O 2.88Å; Q108-T322 HydrophobicContact CB-CG2 3.91Å; Q108-T322 HydrophobicContact CG-CG2 3.69Å
109R97Very high97.9Very high132 Ų13240 Ų4050%0.49821%0.208SC..Hα-helixtrans-59.9-25.7176.2-64.8-67.582.3175-4112.9Y105 N106 G111 T322Y105-R109 HydrophobicContact CD1-CG 4.24Å; Y105-R109 HydrophobicContact CE1-CG 3.95Å; Y105-R109 WeakPolarHBondContact O-CG 3.4Å; Y105-R109 PolarHBondContact O-N 3.46Å; N106-R109 PolarHBondContact O-N 2.85Å; R109-G111 VanDerWaalsContact C-N 3.34Å; R109-T322 VanDerWaalsContact CZ-O 3.28Å; R109-T322 PolarHBondContact NH1-O 2.88Å; R109-T322 PolarHBondContact NH2-O 3.04Å
110Q97.2Very high97.7Very high124 Ų12442.5 Ų42.558%0.57922%0.22SC*.THydrogen-bonded Turntrans-86.5-0.4174.1-65.5169.810.500113.5N106 A107 Q108 R112N106-Q110 WeakPolarHBondContact O-CG 3.44Å; N106-Q110 PolarHBondContact O-N 3.45Å; N106-Q110 VanDerWaalsContact O-N 3.1Å; A107-Q110 PolarHBondContact O-N 2.87Å; Q108-Q110 PolarHBondContact O-N 3.39Å; Q108-Q110 VanDerWaalsContact O-N 3.17Å; Q110-R112 VanDerWaalsContact C-N 3.26Å; Q110-R112 HydrophobicContact CB-CG 3.99Å; Q110-R112 PolarHBondContact O-N 3.42Å; Q110-R112 VanDerWaalsContact OE1-NH1 3.11Å
111G96.3Very high97.6Very high64 Ų6442.6 Ų42.666%0.6622%0.221SC*.THydrogen-bonded Turntrans7313-177.200000114.7A107 Q108 R109A107-G111 PolarHBondContact O-N 2.82Å; Q108-G111 WeakPolarHBondContact O-CA 3.3Å; Q108-G111 PolarHBondContact O-N 3.31Å; R109-G111 VanDerWaalsContact C-N 3.34Å
112R96.6Very high97.5Very high102 Ų10242.2 Ų42.239%0.38522%0.219SC..SBendtrans-77.3-28.9-177.7-63.7165.767.1-177.70112.5A107 Q110 E382A107-R112 HydrophobicContact CB-CB 4.36Å; A107-R112 WeakPolarHBondContact O-CB 3.28Å; A107-R112 PolarHBondContact O-N 3.32Å; Q110-R112 VanDerWaalsContact C-N 3.26Å; Q110-R112 HydrophobicContact CB-CG 3.99Å; Q110-R112 PolarHBondContact O-N 3.42Å; Q110-R112 VanDerWaalsContact OE1-NH1 3.11Å; R112-E382 WeakPolarHBondContact CB-OE1 3.48Å; R112-E382 IonicContact CZ-OE1 3.18Å; R112-E382 IonicContact CZ-OE2 2.64Å; R112-E382 IonicContact NE-OE1 3.77Å; R112-E382 PolarHBondContact NE-OE1 3.14Å; R112-E382 IonicContact NE-OE2 3.15Å; R112-E382 IonicContact NH2-OE1 2.87Å; R112-E382 PolarHBondContact NH2-OE1 3.44Å; R112-E382 IonicContact NH2-OE2 2.74Å; R112-E382 PolarHBondContact NH2-OE2 2.93Å
113I97.7Very high97.5Very high6 Ų638.6 Ų38.63%0.03120%0.202CC..SBendtrans-126.3156165.963.7175.3000108.7L104 A107 Q108 Y116 C163 V164L104-I113 HydrophobicContact CB-CD1 4.23Å; L104-I113 WeakPolarHBondContact O-CD1 3.44Å; A107-I113 HydrophobicContact CB-CG1 4.45Å; Q108-I113 HydrophobicContact CB-CD1 4.07Å; Q108-I113 HydrophobicContact CB-CG1 3.62Å; Q108-I113 HydrophobicContact CG-CG1 4.11Å; I113-Y116 HydrophobicContact CD1-CD2 3.99Å; I113-Y116 HydrophobicContact CD1-CG 4.34Å; I113-C163 HydrophobicContact CD1-CB 4.33Å; I113-C163 HydrophobicContact CG2-CB 4.38Å; I113-V164 HydrophobicContact CG2-CG2 3.94Å
114S97.5Very high97.5Very high91 Ų9137.7 Ų37.764%0.63620%0.197SC*.SBendtrans-80.7-31.8-170.755.10000114.1Q108 P177Q108-S114 PolarHBondContact NE2-O 2.88Å; S114-P177 WeakPolarHBondContact OG-CD 3.45Å; S114-P177 VanDerWaalsContact OG-CG 3.31Å; S114-P177 WeakPolarHBondContact OG-CG 3.24Å
115F98.5Very high97.5Very high31 Ų3137.7 Ų37.714%0.13620%0.197CC..  trans-152.2152.5-173.3-179.7-104.5000110.6M117 M176 P177 S321F115-M117 HydrophobicContact CD1-CG 4.46Å; F115-M117 HydrophobicContact CE1-CG 3.42Å; F115-M117 VanDerWaalsContact CE1-CG 3.42Å; F115-M117 HydrophobicContact CE1-SD 3.66Å; F115-M117 HydrophobicContact CZ-CG 3.45Å; F115-M117 VanDerWaalsContact CZ-CG 3.45Å; F115-M117 HydrophobicContact CZ-SD 3.67Å; F115-M176 HydrophobicContact CB-CG 4Å; F115-M176 HydrophobicContact CB-SD 4.2Å; F115-M176 HydrophobicContact CD1-CG 3.82Å; F115-M176 HydrophobicContact CD1-SD 3.57Å; F115-M176 VanDerWaalsContact CD1-SD 3.57Å; F115-M176 HydrophobicContact CD2-SD 4.26Å; F115-M176 HydrophobicContact CE1-SD 3.88Å; F115-M176 HydrophobicContact CG-CG 4.08Å; F115-M176 HydrophobicContact CG-SD 3.76Å; F115-M176 HydrophobicContact CZ-SD 4.36Å; F115-P177 HydrophobicContact CB-CB 4.4Å; F115-P177 HydrophobicContact CB-CG 4.29Å; F115-P177 WeakPolarHBondContact O-CB 3.37Å; F115-S321 VanDerWaalsContact CE2-CB 3.45Å
116Y98.5Very high97.5Very high1 Ų135.3 Ų35.30%0.00419%0.188CC..  trans-156.6154.7170.5-159.1-105.4000112D101 L104 I113 T118 V178 T322D101-Y116 HydrophobicContact CB-CE1 4.39Å; D101-Y116 WeakPolarHBondContact OD1-CE1 3.49Å; D101-Y116 PolarHBondContact OD1-OH 2.8Å; L104-Y116 HydrophobicContact CB-CD1 4.13Å; L104-Y116 HydrophobicContact CB-CD2 3.75Å; L104-Y116 HydrophobicContact CB-CE1 3.9Å; L104-Y116 HydrophobicContact CB-CE2 3.46Å; L104-Y116 VanDerWaalsContact CB-CE2 3.46Å; L104-Y116 HydrophobicContact CB-CG 4.08Å; L104-Y116 HydrophobicContact CD1-CD2 4.28Å; L104-Y116 HydrophobicContact CD1-CE2 3.43Å; L104-Y116 VanDerWaalsContact CD1-CE2 3.43Å; L104-Y116 HydrophobicContact CG-CE2 4.09Å; I113-Y116 HydrophobicContact CD1-CD2 3.99Å; I113-Y116 HydrophobicContact CD1-CG 4.34Å; Y116-T118 HydrophobicContact CD1-CG2 4.31Å; Y116-T118 HydrophobicContact CE1-CG2 4.27Å; Y116-V178 HydrophobicContact CD2-CG2 3.56Å; Y116-V178 HydrophobicContact CE2-CG2 3.76Å; Y116-V178 HydrophobicContact CG-CG2 4.3Å; Y116-T322 PolarHBondContact N-OG1 3.49Å; Y116-T322 VanDerWaalsContact N-OG1 3.08Å; Y116-T322 WeakPolarHBondContact O-CG2 3.5Å; Y116-T322 PolarHBondContact O-N 3.01Å; Y116-T322 PolarHBondContact O-OG1 2.86Å
117M97.8Very high97.5Very high7 Ų732 Ų323%0.03417%0.17CC..  trans-135131.5175.4-60.8-1798100109.2F115 Y143 H320F115-M117 HydrophobicContact CD1-CG 4.46Å; F115-M117 HydrophobicContact CE1-CG 3.42Å; F115-M117 VanDerWaalsContact CE1-CG 3.42Å; F115-M117 HydrophobicContact CE1-SD 3.66Å; F115-M117 HydrophobicContact CZ-CG 3.45Å; F115-M117 VanDerWaalsContact CZ-CG 3.45Å; F115-M117 HydrophobicContact CZ-SD 3.67Å; M117-Y143 HydrophobicContact CE-CD1 4.49Å; M117-Y143 HydrophobicContact CE-CD2 3.26Å; M117-Y143 HydrophobicContact CE-CE2 3.36Å; M117-Y143 HydrophobicContact CE-CG 3.93Å; M117-Y143 HydrophobicContact SD-CD2 3.65Å; M117-Y143 HydrophobicContact SD-CE2 4.34Å; M117-Y143 HydrophobicContact SD-CG 3.82Å; M117-H320 WeakPolarHBondContact CE-O 3.25Å
118T97.6Very high97.5Very high18 Ų1831.9 Ų31.911%0.1117%0.169CC..  trans-92.1160.6179.461.90000111.7D101 Y105 Y116 R144D101-T118 HydrophobicContact CB-CG2 4.04Å; Y105-T118 HydrophobicContact CD2-CG2 3.81Å; Y105-T118 HydrophobicContact CG-CG2 4.24Å; Y116-T118 HydrophobicContact CD1-CG2 4.31Å; Y116-T118 HydrophobicContact CE1-CG2 4.27Å; T118-R144 PolarHBondContact O-NH1 2.94Å
119N97.6Very high97.5Very high4 Ų430.7 Ų30.72%0.02116%0.164CC..  trans-108.911.1-177.6-53.9-87.1000111.8M97 D101 G121 E122 R144M97-N119 HydrophobicContact CE-CB 3.98Å; M97-N119 HydrophobicContact CG-CB 4.23Å; M97-N119 HydrophobicContact SD-CB 3.92Å; D101-N119 PolarHBondContact OD1-ND2 2.99Å; D101-N119 WeakPolarHBondContact OD2-CB 3.23Å; D101-N119 PolarHBondContact OD2-N 2.93Å; D101-N119 PolarHBondContact OD2-ND2 3.46Å; D101-N119 VanDerWaalsContact OD2-ND2 3.1Å; N119-G121 PolarHBondContact O-N 3.5Å; N119-E122 PolarHBondContact O-N 3.19Å; N119-R144 WeakPolarHBondContact OD1-CA 3.25Å; N119-R144 PolarHBondContact OD1-O 3.36Å
120L95Very high97.6Very high60 Ų6024.5 Ų24.531%0.31414%0.14SC..THydrogen-bonded Turntrans-60.9121.3-171.9-168.372.5000111.8E123 L317L120-E123 WeakPolarHBondContact CA-OE1 3.49Å; L120-L317 HydrophobicContact CB-CB 4.22Å; L120-L317 HydrophobicContact CD2-CB 3.7Å; L120-L317 HydrophobicContact CG-CB 3.72Å; L120-L317 HydrophobicContact CG-CD1 4.08Å; L120-L317 WeakPolarHBondContact O-CB 3.38Å; L120-L317 PolarHBondContact O-N 3.46Å
121G95.7Very high97.6Very high1 Ų119.1 Ų19.11%0.0112%0.118CC..THydrogen-bonded Turntrans95.7-18.3-175.100000114.1N119 E123 N286 T314N119-G121 PolarHBondContact O-N 3.5Å; G121-E123 WeakPolarHBondContact CA-OE2 3.33Å; G121-E123 VanDerWaalsContact N-CD 3.32Å; G121-E123 PolarHBondContact N-OE1 3.32Å; G121-E123 PolarHBondContact N-OE2 2.9Å; G121-N286 PolarHBondContact O-OD1 3.02Å; G121-T314 PolarHBondContact O-OG1 3.37Å
122E97.8Very high97.7Very high1 Ų116.3 Ų16.31%0.0059%0.088CC..  trans-110.713.5-174.9-52.7-164.7-122.200112.6N119 A124 C125 T126 R144 R250 N252 T314N119-E122 PolarHBondContact O-N 3.19Å; E122-A124 PolarHBondContact O-N 2.86Å; E122-C125 WeakPolarHBondContact O-CB 3.35Å; E122-C125 PolarHBondContact O-N 3.48Å; E122-T126 PolarHBondContact O-N 3.32Å; E122-T126 PolarHBondContact O-OG1 2.85Å; E122-R144 WeakPolarHBondContact OE1-CD 3.13Å; E122-R144 IonicContact OE1-NE 3.61Å; E122-R250 IonicContact OE1-NH1 3.92Å; E122-R250 PolarHBondContact OE1-NH1 3.28Å; E122-R250 WeakPolarHBondContact OE2-CB 3.41Å; E122-R250 VanDerWaalsContact OE2-CD 3.26Å; E122-R250 WeakPolarHBondContact OE2-CD 3.44Å; E122-R250 IonicContact OE2-CZ 3.52Å; E122-R250 IonicContact OE2-NE 3.04Å; E122-R250 IonicContact OE2-NH1 3.59Å; E122-R250 PolarHBondContact OE2-NH1 3.39Å; E122-N252 PolarHBondContact OE1-ND2 3.27Å; E122-T314 HydrophobicContact CG-CG2 3.93Å
123E97.8Very high97.7Very high3 Ų312 Ų121%0.0147%0.073CC..Hα-helixtrans-67.8-40.9-172.8-52.191.6150.900112.1M94 M97 L120 G121 C125 T126 I127 P344M94-E123 HydrophobicContact CB-CB 4.26Å; M94-E123 HydrophobicContact CE-CB 3.82Å; M94-E123 HydrophobicContact CG-CB 3.98Å; M97-E123 HydrophobicContact CE-CB 3.28Å; M97-E123 HydrophobicContact CE-CG 3.28Å; L120-E123 WeakPolarHBondContact CA-OE1 3.49Å; G121-E123 WeakPolarHBondContact CA-OE2 3.33Å; G121-E123 VanDerWaalsContact N-CD 3.32Å; G121-E123 PolarHBondContact N-OE1 3.32Å; G121-E123 PolarHBondContact N-OE2 2.9Å; E123-C125 VanDerWaalsContact C-N 3.34Å; E123-C125 PolarHBondContact O-N 3.48Å; E123-T126 PolarHBondContact O-N 2.81Å; E123-T126 PolarHBondContact O-OG1 2.83Å; E123-I127 WeakPolarHBondContact O-CB 3.29Å; E123-I127 WeakPolarHBondContact O-CG1 3.45Å; E123-I127 PolarHBondContact O-N 2.89Å; E123-P344 WeakPolarHBondContact OE2-CG 3.38Å
124A97.8Very high97.7Very high0 Ų016.4 Ų16.40%09%0.093CC..Hα-helixtrans-65.2-37.9176.600000112.1M94 E122 T126 G128 G285 I288 P344M94-A124 HydrophobicContact CE-CB 4.33Å; E122-A124 PolarHBondContact O-N 2.86Å; A124-T126 VanDerWaalsContact C-N 3.33Å; A124-T126 PolarHBondContact O-N 3.01Å; A124-G128 WeakPolarHBondContact O-CA 3.49Å; A124-G128 PolarHBondContact O-N 2.83Å; A124-G285 WeakPolarHBondContact CB-O 3.39Å; A124-I288 HydrophobicContact CB-CB 3.78Å; A124-I288 HydrophobicContact CB-CD1 4.44Å; A124-I288 HydrophobicContact CB-CG1 4.16Å; A124-P344 HydrophobicContact CB-CB 3.49Å; A124-P344 VanDerWaalsContact CB-CB 3.49Å; A124-P344 HydrophobicContact CB-CG 4.45Å
125C98.3Very high97.7Very high0 Ų016.8 Ų16.80%09%0.088CC..Hα-helixtrans-58.1-46.6177.3-74.30000111.2E122 E123 S129 F248 R250 G285E122-C125 WeakPolarHBondContact O-CB 3.35Å; E122-C125 PolarHBondContact O-N 3.48Å; E123-C125 VanDerWaalsContact C-N 3.34Å; E123-C125 PolarHBondContact O-N 3.48Å; C125-S129 VanDerWaalsContact O-CB 3.23Å; C125-S129 WeakPolarHBondContact O-CB 3.2Å; C125-S129 PolarHBondContact O-N 2.72Å; C125-S129 PolarHBondContact O-OG 3.19Å; C125-F248 HydrophobicContact CB-CE1 4.05Å; C125-F248 HydrophobicContact CB-CZ 4.3Å; C125-R250 HydrophobicContact CB-CG 4.4Å; C125-G285 VanDerWaalsContact SG-CA 3.52Å; C125-G285 PolarHBondContact SG-O 3.02Å
126T98.2Very high97.6Very high0 Ų020.1 Ų20.10%010%0.104CC..Hα-helixtrans-84.4-41.6-171.755.70000112.6E122 E123 A124 S129 A130 R144E122-T126 PolarHBondContact O-N 3.32Å; E122-T126 PolarHBondContact O-OG1 2.85Å; E123-T126 PolarHBondContact O-N 2.81Å; E123-T126 PolarHBondContact O-OG1 2.83Å; A124-T126 VanDerWaalsContact C-N 3.33Å; A124-T126 PolarHBondContact O-N 3.01Å; T126-S129 PolarHBondContact O-OG 2.92Å; T126-A130 WeakPolarHBondContact O-CB 3.48Å; T126-A130 PolarHBondContact O-N 3.33Å; T126-R144 VanDerWaalsContact CG2-O 3.29Å; T126-R144 WeakPolarHBondContact CG2-O 3.44Å
127I98.6Very high97.6Very high0 Ų020.1 Ų20.10%010%0.104CC..Hα-helixtrans-72.5-46176.4-63.5-61000111.6M90 N93 M94 M97 E123 S129 A130 A131 G147 W151 I288M90-I127 HydrophobicContact CB-CG2 4.07Å; M90-I127 HydrophobicContact CG-CG2 4.08Å; N93-I127 HydrophobicContact CB-CD1 3.67Å; N93-I127 HydrophobicContact CB-CG1 4.23Å; N93-I127 HydrophobicContact CB-CG2 4.29Å; M94-I127 HydrophobicContact CG-CB 4.45Å; M94-I127 HydrophobicContact CG-CG1 4.16Å; M97-I127 HydrophobicContact CE-CG1 4.44Å; E123-I127 WeakPolarHBondContact O-CB 3.29Å; E123-I127 WeakPolarHBondContact O-CG1 3.45Å; E123-I127 PolarHBondContact O-N 2.89Å; I127-S129 VanDerWaalsContact C-N 3.33Å; I127-S129 PolarHBondContact O-N 3.09Å; I127-A130 PolarHBondContact O-N 2.81Å; I127-A131 WeakPolarHBondContact O-CB 3.46Å; I127-A131 PolarHBondContact O-N 3.23Å; I127-G147 WeakPolarHBondContact CD1-O 3.46Å; I127-W151 HydrophobicContact CG2-CE3 3.95Å; I127-W151 HydrophobicContact CG2-CZ3 4.17Å; I127-I288 HydrophobicContact CB-CD1 4.43Å; I127-I288 HydrophobicContact CG2-CD1 4.17Å
128G97.9Very high97.7Very high0 Ų021 Ų210%011%0.109CC..Hα-helixtrans-63.5-39.3-17800000112.5A124 A132A124-G128 WeakPolarHBondContact O-CA 3.49Å; A124-G128 PolarHBondContact O-N 2.83Å; G128-A132 PolarHBondContact O-N 3.33Å
129S98.4Very high97.7Very high0 Ų020.2 Ų20.20%010%0.104CC..Hα-helixtrans-71.4-43.6178.153.90000111.9C125 T126 I127 A131 A132 Y220 I291C125-S129 VanDerWaalsContact O-CB 3.23Å; C125-S129 WeakPolarHBondContact O-CB 3.2Å; C125-S129 PolarHBondContact O-N 2.72Å; C125-S129 PolarHBondContact O-OG 3.19Å; T126-S129 PolarHBondContact O-OG 2.92Å; I127-S129 VanDerWaalsContact C-N 3.33Å; I127-S129 PolarHBondContact O-N 3.09Å; S129-A131 VanDerWaalsContact C-N 3.26Å; S129-A131 PolarHBondContact O-N 3.43Å; S129-A132 PolarHBondContact O-N 2.68Å; S129-Y220 WeakPolarHBondContact CB-OH 3.41Å; S129-Y220 WeakPolarHBondContact OG-CE1 3.33Å; S129-Y220 PolarHBondContact OG-OH 3.24Å; S129-I291 VanDerWaalsContact N-CG2 3.33Å
130A98.5Very high97.8Very high1 Ų120.5 Ų20.51%0.00811%0.105CC..Hα-helixtrans-60.9-36.1175.500000112.6T126 I127 A132 L133 P148 W151T126-A130 WeakPolarHBondContact O-CB 3.48Å; T126-A130 PolarHBondContact O-N 3.33Å; I127-A130 PolarHBondContact O-N 2.81Å; A130-A132 VanDerWaalsContact C-N 3.26Å; A130-A132 PolarHBondContact O-N 3.25Å; A130-L133 PolarHBondContact O-N 3.08Å; A130-P148 HydrophobicContact CB-CB 3.87Å; A130-P148 HydrophobicContact CB-CG 4.03Å; A130-W151 HydrophobicContact CB-CB 3.85Å; A130-W151 HydrophobicContact CB-CG 3.93Å
131A97.7Very high98Very high12 Ų1217.9 Ų17.910%0.0999%0.092CC..Hα-helixtrans-64.5-27.2177.800000114.5M90 I127 S129 W151 Y292M90-A131 HydrophobicContact CE-CB 3.38Å; I127-A131 WeakPolarHBondContact O-CB 3.46Å; I127-A131 PolarHBondContact O-N 3.23Å; S129-A131 VanDerWaalsContact C-N 3.26Å; S129-A131 PolarHBondContact O-N 3.43Å; A131-W151 VanDerWaalsContact CA-CZ2 3.5Å; A131-W151 HydrophobicContact CB-CD2 4.08Å; A131-W151 HydrophobicContact CB-CE3 4.28Å; A131-W151 HydrophobicContact CB-CH2 3.5Å; A131-W151 HydrophobicContact CB-CZ2 3.28Å; A131-W151 HydrophobicContact CB-CZ3 4.02Å; A131-Y292 HydrophobicContact CB-CD2 3.86Å; A131-Y292 HydrophobicContact CB-CE2 4.12Å; A131-Y292 WeakPolarHBondContact O-CE2 3.23Å
132A97.2Very high98.1Very high5 Ų518 Ų184%0.0419%0.093CC..THydrogen-bonded Turntrans-88.5-7.6179.900000113.8G128 S129 A130 Y292 V295 E296G128-A132 PolarHBondContact O-N 3.33Å; S129-A132 PolarHBondContact O-N 2.68Å; A130-A132 VanDerWaalsContact C-N 3.26Å; A130-A132 PolarHBondContact O-N 3.25Å; A132-Y292 HydrophobicContact CB-CD2 3.76Å; A132-Y292 HydrophobicContact CB-CE2 4.02Å; A132-Y292 HydrophobicContact CB-CG 4.3Å; A132-Y292 WeakPolarHBondContact CB-O 3.38Å; A132-V295 HydrophobicContact CB-CB 3.73Å; A132-V295 HydrophobicContact CB-CG1 3.72Å; A132-E296 HydrophobicContact CB-CB 4.11Å
133L98.1Very high98.1Very high11 Ų1119.9 Ų19.96%0.05810%0.1CC..SBendtrans-90.1160.4177-66179.5000111.7A130 D137 I139 V216 L218 I246 V295A130-L133 PolarHBondContact O-N 3.08Å; L133-D137 HydrophobicContact CB-CB 4.24Å; L133-D137 HydrophobicContact CD1-CB 4.47Å; L133-D137 HydrophobicContact CD2-CB 4.26Å; L133-I139 HydrophobicContact CD1-CD1 3.93Å; L133-I139 HydrophobicContact CD1-CG1 3.98Å; L133-V216 HydrophobicContact CD2-CG2 4.1Å; L133-L218 HydrophobicContact CD1-CB 3.91Å; L133-L218 HydrophobicContact CD1-CD1 3.95Å; L133-L218 HydrophobicContact CD1-CG 4.41Å; L133-L218 HydrophobicContact CD2-CB 4.38Å; L133-L218 HydrophobicContact CD2-CD1 4.06Å; L133-L218 HydrophobicContact CG-CD1 4.28Å; L133-I246 HydrophobicContact CD2-CD1 4.44Å; L133-V295 HydrophobicContact CD2-CG1 4.04Å; L133-V295 HydrophobicContact CG-CG1 4.33Å
134Q97.7Very high98.1Very high99 Ų9919.9 Ų19.946%0.46310%0.099SC..  trans-83.8161.2164.7-58.9-58.2-53.100110.2E136 D137 R152 R299Q134-E136 PolarHBondContact O-N 2.9Å; Q134-D137 PolarHBondContact N-OD2 2.94Å; Q134-D137 PolarHBondContact O-N 3.45Å; Q134-R152 PolarHBondContact O-NH2 3.15Å; Q134-R299 VanDerWaalsContact CG-CZ 3.43Å
135D97.2Very high98.1Very high99 Ų9919.9 Ų19.953%0.52910%0.1SC..THydrogen-bonded Turntrans-65.6-28.6-179.4-77.4-22000112N186D135-N186 PolarHBondContact O-ND2 3.12Å
136E97.1Very high98.1Very high101 Ų10120.1 Ų20.147%0.47210%0.101SC..THydrogen-bonded Turntrans-74.3-22.2177.1-66.271.9-154.400113.7Q134 L138 R215Q134-E136 PolarHBondContact O-N 2.9Å; E136-L138 PolarHBondContact O-N 3.3Å; E136-R215 VanDerWaalsContact O-CD 3.28Å; E136-R215 WeakPolarHBondContact O-CD 3.46Å; E136-R215 WeakPolarHBondContact O-CG 3.47Å; E136-R215 PolarHBondContact O-NE 2.92Å; E136-R215 PolarHBondContact O-NH2 3.31Å
137D98.6Very high98.1Very high0 Ų020.1 Ų20.10%010%0.101CC..SBendtrans-63.5134.6-178.6-67.1-37.1000110.1L133 Q134 R152 V216 R299L133-D137 HydrophobicContact CB-CB 4.24Å; L133-D137 HydrophobicContact CD1-CB 4.47Å; L133-D137 HydrophobicContact CD2-CB 4.26Å; Q134-D137 PolarHBondContact N-OD2 2.94Å; Q134-D137 PolarHBondContact O-N 3.45Å; D137-R152 VanDerWaalsContact O-CZ 3.3Å; D137-R152 PolarHBondContact O-NH1 2.76Å; D137-R152 PolarHBondContact O-NH2 2.86Å; D137-V216 WeakPolarHBondContact CA-O 3.5Å; D137-V216 HydrophobicContact CB-CG2 4.03Å; D137-V216 WeakPolarHBondContact OD1-CG2 3.34Å; D137-V216 PolarHBondContact OD1-N 2.89Å; D137-R299 IonicContact OD1-NE 3.69Å; D137-R299 IonicContact OD1-NH2 2.72Å; D137-R299 PolarHBondContact OD1-NH2 2.83Å; D137-R299 IonicContact OD2-CZ 2.83Å; D137-R299 IonicContact OD2-NE 3.66Å; D137-R299 PolarHBondContact OD2-NE 3.27Å; D137-R299 IonicContact OD2-NH2 3.51Å
138L98.6Very high98.1Very high27 Ų2720.1 Ų20.114%0.14110%0.101CC..EExtended strand (participates in β ladder)trans-89.3130.2-174-16966.7000110.4E136 F140 N186 V188 S204 V216 S217 L218E136-L138 PolarHBondContact O-N 3.3Å; L138-F140 HydrophobicContact CB-CE2 4.45Å; L138-F140 HydrophobicContact CD2-CE2 3.49Å; L138-F140 VanDerWaalsContact CD2-CE2 3.49Å; L138-F140 HydrophobicContact CD2-CZ 3.72Å; L138-F140 HydrophobicContact CG-CD2 4.41Å; L138-F140 HydrophobicContact CG-CE2 3.82Å; L138-F140 HydrophobicContact CG-CZ 4.41Å; L138-N186 HydrophobicContact CD1-CB 4.04Å; L138-V188 HydrophobicContact CD1-CG2 3.82Å; L138-V188 HydrophobicContact CD2-CG2 3.98Å; L138-V188 HydrophobicContact CG-CG2 3.86Å; L138-S204 WeakPolarHBondContact CD2-OG 3.38Å; L138-V216 PolarHBondContact N-O 3.18Å; L138-S217 CarbonylContact O-C 3.59Å; L138-S217 VanDerWaalsContact O-CA 3.31Å; L138-S217 WeakPolarHBondContact O-CA 3.43Å; L138-L218 PolarHBondContact O-N 3.06Å
139I98.9Very high98.1Very high0 Ų020.1 Ų20.10%010%0.101CC..EExtended strand (participates in β ladder)trans-105.6126.2-178.7-63.5178.4000110.2L133 P148 N186 Y187 V188 L218 Y220L133-I139 HydrophobicContact CD1-CD1 3.93Å; L133-I139 HydrophobicContact CD1-CG1 3.98Å; I139-P148 HydrophobicContact CD1-CB 3.6Å; I139-P148 HydrophobicContact CD1-CG 4.27Å; I139-N186 PolarHBondContact N-O 3.29Å; I139-Y187 HydrophobicContact CB-CD2 4.08Å; I139-Y187 HydrophobicContact CG2-CD2 3.78Å; I139-Y187 HydrophobicContact CG2-CE2 3.88Å; I139-V188 PolarHBondContact O-N 3.36Å; I139-L218 WeakPolarHBondContact CA-O 3.32Å; I139-Y220 HydrophobicContact CG2-CD2 3.93Å; I139-Y220 HydrophobicContact CG2-CE2 3.64Å
140F98.9Very high98.1Very high10 Ų1020.6 Ų20.64%0.04410%0.103CC..EExtended strand (participates in β ladder)trans-107.4119.6168-68.6-100.6000108.5L138 V188 Q197 Q200 A201 L218 C219 Y220L138-F140 HydrophobicContact CB-CE2 4.45Å; L138-F140 HydrophobicContact CD2-CE2 3.49Å; L138-F140 VanDerWaalsContact CD2-CE2 3.49Å; L138-F140 HydrophobicContact CD2-CZ 3.72Å; L138-F140 HydrophobicContact CG-CD2 4.41Å; L138-F140 HydrophobicContact CG-CE2 3.82Å; L138-F140 HydrophobicContact CG-CZ 4.41Å; F140-V188 HydrophobicContact CD1-CB 4.02Å; F140-V188 HydrophobicContact CD1-CG1 4.06Å; F140-V188 HydrophobicContact CD1-CG2 3.97Å; F140-V188 HydrophobicContact CD2-CG2 4.36Å; F140-V188 HydrophobicContact CE1-CB 4.17Å; F140-V188 HydrophobicContact CE1-CG1 4.01Å; F140-V188 HydrophobicContact CE1-CG2 3.75Å; F140-V188 HydrophobicContact CE2-CG2 4.15Å; F140-V188 HydrophobicContact CG-CB 4.46Å; F140-V188 HydrophobicContact CG-CG2 4.28Å; F140-V188 HydrophobicContact CZ-CG2 3.84Å; F140-Q197 HydrophobicContact CB-CB 4.18Å; F140-Q197 HydrophobicContact CB-CG 4.06Å; F140-Q197 HydrophobicContact CD1-CB 4.19Å; F140-Q200 HydrophobicContact CD1-CB 4.4Å; F140-Q200 HydrophobicContact CE1-CB 3.92Å; F140-A201 HydrophobicContact CB-CB 4.12Å; F140-A201 HydrophobicContact CD1-CB 4.22Å; F140-A201 HydrophobicContact CD2-CB 3.45Å; F140-A201 VanDerWaalsContact CD2-CB 3.45Å; F140-A201 VanDerWaalsContact CE2-CA 3.49Å; F140-A201 HydrophobicContact CE2-CB 3.8Å; F140-A201 HydrophobicContact CG-CB 3.67Å; F140-A201 HydrophobicContact CZ-CB 4.33Å; F140-L218 PolarHBondContact N-O 3.43Å; F140-C219 HydrophobicContact CB-CB 4.33Å; F140-C219 WeakPolarHBondContact O-CA 3.46Å; F140-Y220 PolarHBondContact O-N 2.93Å
141A98.5Very high98.1Very high6 Ų621.2 Ų21.25%0.0511%0.105CC..  trans-110.9164.9-173.700000112.2E145 Y187 I190A141-E145 HydrophobicContact CB-CB 3.71Å; A141-E145 HydrophobicContact CB-CG 3.94Å; A141-Y187 HydrophobicContact CB-CE1 3.77Å; A141-Y187 HydrophobicContact CB-CE2 4.11Å; A141-Y187 WeakPolarHBondContact CB-OH 3.49Å; A141-I190 HydrophobicContact CB-CD1 4.1Å; A141-I190 HydrophobicContact CB-CG1 3.82Å
142Q98.3Very high98.1Very high4 Ų421.4 Ų21.42%0.01910%0.103CC..  trans-105.1-60.3177.9-168.8-170.215.100111.5E145 I190 L194 R250Q142-E145 WeakPolarHBondContact CA-OE2 3.32Å; Q142-E145 PolarHBondContact N-OE2 2.67Å; Q142-I190 WeakPolarHBondContact O-CG2 3.36Å; Q142-L194 HydrophobicContact CG-CD2 4.15Å; Q142-R250 VanDerWaalsContact OE1-NH2 3.1Å
143Y97.6Very high98.1Very high40 Ų4023.6 Ų23.616%0.15713%0.127CC..SBendtrans177.1-5.5174.849-113.8000113.8M117 E145 V178 L194M117-Y143 HydrophobicContact CE-CD1 4.49Å; M117-Y143 HydrophobicContact CE-CD2 3.26Å; M117-Y143 HydrophobicContact CE-CE2 3.36Å; M117-Y143 HydrophobicContact CE-CG 3.93Å; M117-Y143 HydrophobicContact SD-CD2 3.65Å; M117-Y143 HydrophobicContact SD-CE2 4.34Å; M117-Y143 HydrophobicContact SD-CG 3.82Å; Y143-E145 PolarHBondContact N-OE2 2.98Å; Y143-V178 WeakPolarHBondContact O-CG1 3.12Å; Y143-L194 HydrophobicContact CD1-CD2 4.42Å; Y143-L194 HydrophobicContact CE1-CD2 3.65Å
144R97.5Very high98.1Very high2 Ų224.2 Ų24.21%0.00813%0.128CC..SBendtrans-112.525.4175.9-56.8-162.2-169.7-79.7-12.8112.4T118 N119 E122 T126 H320T118-R144 PolarHBondContact O-NH1 2.94Å; N119-R144 WeakPolarHBondContact OD1-CA 3.25Å; N119-R144 PolarHBondContact OD1-O 3.36Å; E122-R144 WeakPolarHBondContact OE1-CD 3.13Å; E122-R144 IonicContact OE1-NE 3.61Å; T126-R144 VanDerWaalsContact CG2-O 3.29Å; T126-R144 WeakPolarHBondContact CG2-O 3.44Å; R144-H320 PolarHBondContact NH1-O 3.45Å; R144-H320 PolarHBondContact NH2-ND1 3.05Å; R144-H320 PolarHBondContact NH2-O 2.86Å
145E98.2Very high98Very high1 Ų122.3 Ų22.31%0.00513%0.126CC..  trans-10746.2-174.6-70.266.7-137.800110.7A141 Q142 Y143 G147 P148 Y187 Y220 R250A141-E145 HydrophobicContact CB-CB 3.71Å; A141-E145 HydrophobicContact CB-CG 3.94Å; Q142-E145 WeakPolarHBondContact CA-OE2 3.32Å; Q142-E145 PolarHBondContact N-OE2 2.67Å; Y143-E145 PolarHBondContact N-OE2 2.98Å; E145-G147 VanDerWaalsContact C-N 3.26Å; E145-P148 HydrophobicContact CB-CG 4.41Å; E145-P148 WeakPolarHBondContact O-CD 3.42Å; E145-Y187 HydrophobicContact CB-CE2 4.36Å; E145-Y187 VanDerWaalsContact CB-OH 3.27Å; E145-Y187 WeakPolarHBondContact CB-OH 3.44Å; E145-Y187 WeakPolarHBondContact O-CE2 3.28Å; E145-Y187 PolarHBondContact O-OH 2.9Å; E145-Y220 HydrophobicContact CB-CD2 4.31Å; E145-Y220 HydrophobicContact CG-CD1 3.92Å; E145-Y220 HydrophobicContact CG-CD2 3.38Å; E145-Y220 HydrophobicContact CG-CE1 4.45Å; E145-Y220 HydrophobicContact CG-CE2 3.93Å; E145-Y220 HydrophobicContact CG-CG 3.35Å; E145-Y220 WeakPolarHBondContact OE1-CB 3.16Å; E145-R250 IonicContact OE1-CZ 2.73Å; E145-R250 IonicContact OE1-NE 3.94Å; E145-R250 PolarHBondContact OE1-NE 3.17Å; E145-R250 IonicContact OE1-NH2 3.99Å; E145-R250 PolarHBondContact OE1-NH2 2.93Å; E145-R250 IonicContact OE2-NH2 3.68Å
146L97.9Very high98.1Very high5 Ų518.9 Ų18.93%0.02611%0.107CC..Hα-helixtrans-66-34.7173.6175.954.7000111.1M97 I100 L149 L150 L159 Y180M97-L146 HydrophobicContact CG-CD2 4.01Å; M97-L146 HydrophobicContact CG-CG 4.32Å; M97-L146 HydrophobicContact SD-CB 3.99Å; M97-L146 HydrophobicContact SD-CD2 4.47Å; M97-L146 HydrophobicContact SD-CG 4.19Å; I100-L146 HydrophobicContact CB-CD2 4.5Å; I100-L146 HydrophobicContact CD1-CD2 4.4Å; I100-L146 HydrophobicContact CG2-CD2 4.02Å; L146-L149 HydrophobicContact CD1-CB 4.48Å; L146-L149 WeakPolarHBondContact O-CB 3.41Å; L146-L149 PolarHBondContact O-N 2.98Å; L146-L149 VanDerWaalsContact O-N 3.07Å; L146-L150 HydrophobicContact CD1-CD2 4.08Å; L146-L150 HydrophobicContact CD1-CG 4.08Å; L146-L150 HydrophobicContact CD2-CD1 4.39Å; L146-L150 HydrophobicContact CG-CD1 4.03Å; L146-L150 HydrophobicContact CG-CD2 4.43Å; L146-L150 HydrophobicContact CG-CG 4.03Å; L146-L150 PolarHBondContact O-N 3.23Å; L146-L159 HydrophobicContact CD1-CD1 3.32Å; L146-L159 HydrophobicContact CD1-CG 4.24Å; L146-L159 HydrophobicContact CD2-CD1 4.19Å; L146-L159 HydrophobicContact CG-CD1 4.38Å; L146-Y180 HydrophobicContact CD1-CE2 4.18Å
147G98.2Very high98.2Very high0 Ų016 Ų160%09%0.094CC..Hα-helixtrans-48.8-52.8-17800000114.9I127 E145 L149 L150 W151I127-G147 WeakPolarHBondContact CD1-O 3.46Å; E145-G147 VanDerWaalsContact C-N 3.26Å; G147-L149 VanDerWaalsContact C-N 3.29Å; G147-L149 PolarHBondContact O-N 3.37Å; G147-L150 PolarHBondContact O-N 2.74Å; G147-L150 VanDerWaalsContact O-N 3.14Å; G147-W151 WeakPolarHBondContact O-CB 3.45Å; G147-W151 PolarHBondContact O-N 3.36Å
148P98.6Very high98.1Very high0 Ų017.6 Ų17.60%011%0.105CC..Hα-helixtrans-57.6-34.9177.9-2525.5000115.5A130 I139 E145 R152 Y187 Y220A130-P148 HydrophobicContact CB-CB 3.87Å; A130-P148 HydrophobicContact CB-CG 4.03Å; I139-P148 HydrophobicContact CD1-CB 3.6Å; I139-P148 HydrophobicContact CD1-CG 4.27Å; E145-P148 HydrophobicContact CB-CG 4.41Å; E145-P148 WeakPolarHBondContact O-CD 3.42Å; P148-R152 WeakPolarHBondContact O-CB 3.43Å; P148-R152 WeakPolarHBondContact O-CG 3.37Å; P148-R152 PolarHBondContact O-N 2.85Å; P148-Y187 HydrophobicContact CB-CD2 4.19Å; P148-Y187 HydrophobicContact CB-CE2 4Å; P148-Y187 HydrophobicContact CG-CE2 4.37Å; P148-Y220 HydrophobicContact CG-CE2 3.91Å
149L98.4Very high98.1Very high0 Ų016.3 Ų16.30%010%0.099CC..Hα-helixtrans-66.9-45.4175.7-73.2169.8000110.7L146 G147 W151 R152 G153 Y154 Y180 Y187L146-L149 HydrophobicContact CD1-CB 4.48Å; L146-L149 WeakPolarHBondContact O-CB 3.41Å; L146-L149 PolarHBondContact O-N 2.98Å; L146-L149 VanDerWaalsContact O-N 3.07Å; G147-L149 VanDerWaalsContact C-N 3.29Å; G147-L149 PolarHBondContact O-N 3.37Å; L149-W151 VanDerWaalsContact C-N 3.34Å; L149-R152 PolarHBondContact O-N 2.87Å; L149-G153 PolarHBondContact O-N 2.81Å; L149-Y154 HydrophobicContact CB-CD1 4.32Å; L149-Y154 HydrophobicContact CB-CG 4.27Å; L149-Y154 HydrophobicContact CD1-CD1 4.46Å; L149-Y154 HydrophobicContact CD2-CD1 4.33Å; L149-Y154 HydrophobicContact CD2-CD2 4.24Å; L149-Y154 HydrophobicContact CD2-CG 3.97Å; L149-Y154 WeakPolarHBondContact O-CB 3.12Å; L149-Y154 PolarHBondContact O-N 2.88Å; L149-Y180 VanDerWaalsContact CD1-CB 3.43Å; L149-Y180 HydrophobicContact CD1-CD2 3.93Å; L149-Y180 HydrophobicContact CD1-CG 3.88Å; L149-Y187 HydrophobicContact CD1-CD1 4.45Å; L149-Y187 HydrophobicContact CD1-CE1 4.17Å; L149-Y187 HydrophobicContact CD1-CE2 4.33Å; L149-Y187 HydrophobicContact CD2-CD1 4.11Å; L149-Y187 HydrophobicContact CD2-CD2 3.88Å; L149-Y187 HydrophobicContact CD2-CE2 4.37Å; L149-Y187 HydrophobicContact CD2-CG 3.7Å; L149-Y187 HydrophobicContact CG-CD1 4.37Å; L149-Y187 HydrophobicContact CG-CD2 3.85Å; L149-Y187 HydrophobicContact CG-CE1 4.38Å; L149-Y187 HydrophobicContact CG-CE2 3.84Å; L149-Y187 HydrophobicContact CG-CG 4.09Å
150L98.1Very high98Very high9 Ų916.3 Ų16.35%0.04710%0.099CC..Hα-helixtrans-61.9-44.7176.1-56.9-177.6000111N93 F96 M97 I100 L146 G147 R152 G153 L159N93-L150 PolarHBondContact OD1-O 2.94Å; F96-L150 HydrophobicContact CD1-CD1 4.23Å; F96-L150 HydrophobicContact CD1-CD2 4.1Å; F96-L150 HydrophobicContact CE1-CD2 3.91Å; M97-L150 HydrophobicContact CB-CD1 3.67Å; M97-L150 HydrophobicContact CG-CD1 4.06Å; M97-L150 HydrophobicContact SD-CD1 4.3Å; I100-L150 HydrophobicContact CD1-CD1 4.04Å; I100-L150 HydrophobicContact CD1-CD2 3.7Å; L146-L150 HydrophobicContact CD1-CD2 4.08Å; L146-L150 HydrophobicContact CD1-CG 4.08Å; L146-L150 HydrophobicContact CD2-CD1 4.39Å; L146-L150 HydrophobicContact CG-CD1 4.03Å; L146-L150 HydrophobicContact CG-CD2 4.43Å; L146-L150 HydrophobicContact CG-CG 4.03Å; L146-L150 PolarHBondContact O-N 3.23Å; G147-L150 PolarHBondContact O-N 2.74Å; G147-L150 VanDerWaalsContact O-N 3.14Å; L150-R152 VanDerWaalsContact C-N 3.33Å; L150-R152 PolarHBondContact O-N 2.88Å; L150-G153 PolarHBondContact O-N 3.24Å; L150-L159 HydrophobicContact CD2-CD1 4.21Å
151W98.4Very high98Very high14 Ų1416 Ų165%0.05310%0.098CC..Hα-helixtrans-58.7-43.5179.2-175-98.4000112.6L86 R89 M90 I127 A130 A131 G147 L149 G153L86-W151 HydrophobicContact CD1-CH2 3.63Å; L86-W151 HydrophobicContact CD1-CZ2 3.93Å; R89-W151 HydrophobicContact CB-CH2 4.41Å; R89-W151 HydrophobicContact CB-CZ3 4.36Å; R89-W151 HydrophobicContact CG-CE3 4.49Å; R89-W151 HydrophobicContact CG-CH2 3.97Å; R89-W151 HydrophobicContact CG-CZ3 3.74Å; R89-W151 PolarHBondContact NH2-O 3.24Å; M90-W151 HydrophobicContact CB-CZ3 4.47Å; M90-W151 HydrophobicContact CG-CH2 3.99Å; M90-W151 HydrophobicContact CG-CZ3 3.76Å; I127-W151 HydrophobicContact CG2-CE3 3.95Å; I127-W151 HydrophobicContact CG2-CZ3 4.17Å; A130-W151 HydrophobicContact CB-CB 3.85Å; A130-W151 HydrophobicContact CB-CG 3.93Å; A131-W151 VanDerWaalsContact CA-CZ2 3.5Å; A131-W151 HydrophobicContact CB-CD2 4.08Å; A131-W151 HydrophobicContact CB-CE3 4.28Å; A131-W151 HydrophobicContact CB-CH2 3.5Å; A131-W151 HydrophobicContact CB-CZ2 3.28Å; A131-W151 HydrophobicContact CB-CZ3 4.02Å; G147-W151 WeakPolarHBondContact O-CB 3.45Å; G147-W151 PolarHBondContact O-N 3.36Å; L149-W151 VanDerWaalsContact C-N 3.34Å; W151-G153 PolarHBondContact O-N 2.85Å
152R98.3Very high98Very high16 Ų1616.1 Ų16.16%0.0610%0.097CC..THydrogen-bonded Turntrans-81.210.1178.1-68.6-175170174.2-2.7113.9Q134 D137 P148 L149 L150 K185 N186Q134-R152 PolarHBondContact O-NH2 3.15Å; D137-R152 VanDerWaalsContact O-CZ 3.3Å; D137-R152 PolarHBondContact O-NH1 2.76Å; D137-R152 PolarHBondContact O-NH2 2.86Å; P148-R152 WeakPolarHBondContact O-CB 3.43Å; P148-R152 WeakPolarHBondContact O-CG 3.37Å; P148-R152 PolarHBondContact O-N 2.85Å; L149-R152 PolarHBondContact O-N 2.87Å; L150-R152 VanDerWaalsContact C-N 3.33Å; L150-R152 PolarHBondContact O-N 2.88Å; R152-K185 HydrophobicContact CB-CB 4.14Å; R152-K185 HydrophobicContact CB-CD 4.27Å; R152-K185 HydrophobicContact CB-CG 4.37Å; R152-K185 WeakPolarHBondContact CD-O 3.5Å; R152-K185 PolarHBondContact NH1-O 3.07Å; R152-K185 WeakPolarHBondContact O-CD 3.45Å; R152-K185 WeakPolarHBondContact O-CE 3.48Å; R152-K185 PolarHBondContact O-NZ 2.91Å; R152-N186 PolarHBondContact NH1-O 2.74Å
153G97.3Very high98Very high51 Ų5116.1 Ų16.153%0.52610%0.097SC..THydrogen-bonded Turntrans68.635.3175.100000113.5L149 L150 W151L149-G153 PolarHBondContact O-N 2.81Å; L150-G153 PolarHBondContact O-N 3.24Å; W151-G153 PolarHBondContact O-N 2.85Å
154Y97.6Very high98Very high25 Ų2515 Ų1510%0.0989%0.094CC..  trans-63.5137168.7-168.1-113.5000109.9L149 L156 L159 K185L149-Y154 HydrophobicContact CB-CD1 4.32Å; L149-Y154 HydrophobicContact CB-CG 4.27Å; L149-Y154 HydrophobicContact CD1-CD1 4.46Å; L149-Y154 HydrophobicContact CD2-CD1 4.33Å; L149-Y154 HydrophobicContact CD2-CD2 4.24Å; L149-Y154 HydrophobicContact CD2-CG 3.97Å; L149-Y154 WeakPolarHBondContact O-CB 3.12Å; L149-Y154 PolarHBondContact O-N 2.88Å; Y154-L156 PolarHBondContact O-N 2.85Å; Y154-L159 HydrophobicContact CD1-CB 4.27Å; Y154-L159 HydrophobicContact CE1-CB 4.14Å; Y154-K185 HydrophobicContact CD2-CG 4.15Å
155S96.9Very high98Very high58 Ų5815.6 Ų15.641%0.40610%0.101SC..  trans-65.3129.5-175.2172.50000111.3Q157 S158 L159S155-Q157 PolarHBondContact O-N 2.86Å; S155-Q157 PolarHBondContact OG-N 3.42Å; S155-S158 WeakPolarHBondContact CB-OG 3.35Å; S155-S158 PolarHBondContact O-N 3.46Å; S155-S158 VanDerWaalsContact O-N 3.13Å; S155-S158 PolarHBondContact OG-N 2.79Å; S155-L159 PolarHBondContact O-N 2.89Å
156L98.3Very high97.8Very high27 Ų2715.5 Ų15.514%0.14110%0.101CC..Hα-helixtrans-54-42.4170.6175.859.8000111.5F96 I100 Y154 S158 L159 V160 D373 V374 A377F96-L156 HydrophobicContact CE2-CD1 4.24Å; F96-L156 HydrophobicContact CE2-CD2 4.08Å; F96-L156 HydrophobicContact CZ-CB 4.05Å; F96-L156 HydrophobicContact CZ-CD1 3.92Å; F96-L156 HydrophobicContact CZ-CD2 3.93Å; F96-L156 HydrophobicContact CZ-CG 4.17Å; I100-L156 HydrophobicContact CD1-CD1 4.04Å; I100-L156 HydrophobicContact CG1-CD1 3.95Å; Y154-L156 PolarHBondContact O-N 2.85Å; L156-S158 VanDerWaalsContact C-N 3.32Å; L156-S158 PolarHBondContact O-N 2.84Å; L156-L159 WeakPolarHBondContact O-CB 3.34Å; L156-L159 PolarHBondContact O-N 3.28Å; L156-V160 HydrophobicContact CD1-CG2 4.07Å; L156-V160 WeakPolarHBondContact O-CG2 3.09Å; L156-V160 PolarHBondContact O-N 3.2Å; L156-D373 HydrophobicContact CD2-CB 4.09Å; L156-V374 HydrophobicContact CD1-CG2 4.05Å; L156-V374 HydrophobicContact CD2-CG2 4.14Å; L156-A377 HydrophobicContact CD2-CB 3.99Å; L156-A377 HydrophobicContact CG-CB 3.87Å
157Q98.3Very high97.5Very high40 Ų4018.9 Ų18.919%0.18712%0.116CC..Hα-helixtrans-62.3-43.1179.9-171.361.460.900110.7S155 L159 V160 D161 A377S155-Q157 PolarHBondContact O-N 2.86Å; S155-Q157 PolarHBondContact OG-N 3.42Å; Q157-L159 PolarHBondContact O-N 3.41Å; Q157-V160 PolarHBondContact O-N 3.22Å; Q157-D161 PolarHBondContact NE2-OD1 2.79Å; Q157-D161 VanDerWaalsContact O-CB 3.29Å; Q157-D161 WeakPolarHBondContact O-CB 3.41Å; Q157-D161 PolarHBondContact O-N 3.09Å; Q157-D161 VanDerWaalsContact O-OD2 3.13Å; Q157-A377 PolarHBondContact NE2-O 2.87Å; Q157-A377 VanDerWaalsContact NE2-O 3.12Å; Q157-A377 PolarHBondContact OE1-O 3.34Å
158S97.2Very high97.3Very high35 Ų3523 Ų2325%0.24514%0.138CC..Hα-helixtrans-66.8-34.5178.5-57.60000113S155 L156 Q162S155-S158 WeakPolarHBondContact CB-OG 3.35Å; S155-S158 PolarHBondContact O-N 3.46Å; S155-S158 VanDerWaalsContact O-N 3.13Å; S155-S158 PolarHBondContact OG-N 2.79Å; L156-S158 VanDerWaalsContact C-N 3.32Å; L156-S158 PolarHBondContact O-N 2.84Å; S158-Q162 PolarHBondContact O-N 2.82Å; S158-Q162 VanDerWaalsContact O-N 3.17Å
159L98.1Very high97.1Very high0 Ų023.2 Ų23.20%014%0.14CC..Hα-helixtrans-61.6-50.6172.2-177.2171.8000110.6I100 L104 L146 L150 Y154 S155 L156 Q157 Q162 C163 Y180I100-L159 HydrophobicContact CD1-CD1 4.11Å; I100-L159 HydrophobicContact CG2-CD1 4.38Å; I100-L159 HydrophobicContact CG2-CD2 4.16Å; L104-L159 HydrophobicContact CD1-CD2 3.69Å; L146-L159 HydrophobicContact CD1-CD1 3.32Å; L146-L159 HydrophobicContact CD1-CG 4.24Å; L146-L159 HydrophobicContact CD2-CD1 4.19Å; L146-L159 HydrophobicContact CG-CD1 4.38Å; L150-L159 HydrophobicContact CD2-CD1 4.21Å; Y154-L159 HydrophobicContact CD1-CB 4.27Å; Y154-L159 HydrophobicContact CE1-CB 4.14Å; S155-L159 PolarHBondContact O-N 2.89Å; L156-L159 WeakPolarHBondContact O-CB 3.34Å; L156-L159 PolarHBondContact O-N 3.28Å; Q157-L159 PolarHBondContact O-N 3.41Å; L159-Q162 WeakPolarHBondContact O-CB 3.48Å; L159-Q162 PolarHBondContact O-N 2.86Å; L159-C163 PolarHBondContact O-N 3.08Å; L159-Y180 HydrophobicContact CD2-CE1 4.1Å; L159-Y180 WeakPolarHBondContact CD2-OH 3.34Å; L159-Y180 HydrophobicContact CG-CE1 3.86Å
160V98.4Very high96.8Very high0 Ų028.5 Ų28.50%017%0.172CC..Hα-helixtrans-69.2-36.2-178.9-176.50000111.6L104 L156 Q157 Q162 C163 V164 A377 L378 A381L104-V160 HydrophobicContact CD2-CG1 4.35Å; L104-V160 HydrophobicContact CD2-CG2 4.39Å; L156-V160 HydrophobicContact CD1-CG2 4.07Å; L156-V160 WeakPolarHBondContact O-CG2 3.09Å; L156-V160 PolarHBondContact O-N 3.2Å; Q157-V160 PolarHBondContact O-N 3.22Å; V160-Q162 VanDerWaalsContact C-N 3.27Å; V160-Q162 PolarHBondContact O-N 2.82Å; V160-C163 PolarHBondContact O-N 3.05Å; V160-C163 VanDerWaalsContact O-N 3.17Å; V160-V164 HydrophobicContact CG1-CG2 4.26Å; V160-V164 WeakPolarHBondContact O-CG2 3.31Å; V160-V164 PolarHBondContact O-N 3.2Å; V160-A377 HydrophobicContact CB-CB 4.47Å; V160-A377 HydrophobicContact CG2-CB 4.05Å; V160-L378 HydrophobicContact CG1-CB 4.15Å; V160-L378 HydrophobicContact CG1-CD1 3.86Å; V160-A381 HydrophobicContact CB-CB 4.46Å; V160-A381 HydrophobicContact CG1-CB 3.73Å
161D98.2Very high96.6Very high4 Ų429.5 Ų29.52%0.02119%0.185CC..Hα-helixtrans-58.8-39174.8-71-24.1000111.5Q157 G165 N166 D168 A381 K384Q157-D161 PolarHBondContact NE2-OD1 2.79Å; Q157-D161 VanDerWaalsContact O-CB 3.29Å; Q157-D161 WeakPolarHBondContact O-CB 3.41Å; Q157-D161 PolarHBondContact O-N 3.09Å; Q157-D161 VanDerWaalsContact O-OD2 3.13Å; D161-G165 WeakPolarHBondContact O-CA 3.41Å; D161-G165 PolarHBondContact O-N 3.23Å; D161-N166 WeakPolarHBondContact CA-ND2 3.34Å; D161-N166 WeakPolarHBondContact CB-OD1 3.16Å; D161-N166 PolarHBondContact O-N 3.29Å; D161-N166 PolarHBondContact OD1-ND2 3.23Å; D161-N166 PolarHBondContact OD1-OD1 3.49Å; D161-D168 HydrophobicContact CB-CB 4.39Å; D161-D168 WeakPolarHBondContact OD2-CB 3.31Å; D161-A381 WeakPolarHBondContact OD1-CB 3.34Å; D161-K384 IonicContact OD1-NZ 2.74Å; D161-K384 PolarHBondContact OD1-NZ 3.18Å; D161-K384 IonicContact OD2-NZ 3.58Å; D161-K384 PolarHBondContact OD2-NZ 3.02Å
162Q98.3Very high96.4Very high8 Ų831 Ų314%0.03719%0.193CC..Hα-helixtrans-65-45.6173.6-168.2-76.2-3300112.1S158 L159 V160 V164 G165 M176 Y180S158-Q162 PolarHBondContact O-N 2.82Å; S158-Q162 VanDerWaalsContact O-N 3.17Å; L159-Q162 WeakPolarHBondContact O-CB 3.48Å; L159-Q162 PolarHBondContact O-N 2.86Å; V160-Q162 VanDerWaalsContact C-N 3.27Å; V160-Q162 PolarHBondContact O-N 2.82Å; Q162-V164 VanDerWaalsContact C-N 3.3Å; Q162-V164 PolarHBondContact O-N 3.23Å; Q162-G165 PolarHBondContact O-N 3.15Å; Q162-G165 VanDerWaalsContact O-N 3.12Å; Q162-M176 PolarHBondContact NE2-O 2.91Å; Q162-Y180 HydrophobicContact CB-CD1 4.07Å; Q162-Y180 HydrophobicContact CB-CE1 4.15Å; Q162-Y180 HydrophobicContact CG-CD1 3.96Å; Q162-Y180 HydrophobicContact CG-CE1 4.33Å
163C98.4Very high96.3Very high3 Ų332 Ų322%0.0221%0.208CC..Hα-helixtrans-64.8-34.5178.7-71.70000113I113 L159 V160 P177 Y180I113-C163 HydrophobicContact CD1-CB 4.33Å; I113-C163 HydrophobicContact CG2-CB 4.38Å; L159-C163 PolarHBondContact O-N 3.08Å; V160-C163 PolarHBondContact O-N 3.05Å; V160-C163 VanDerWaalsContact O-N 3.17Å; C163-P177 HydrophobicContact CB-CB 4.33Å; C163-P177 WeakPolarHBondContact O-CG 3.43Å; C163-Y180 PolarHBondContact SG-OH 2.95Å
164V97.6Very high96.2Very high17 Ų1734 Ų3410%0.10320%0.2CC..Hα-helixtrans-78.4-27.1174.5176.30000110.9I113 V160 Q162 N166 L378 A381 E382 K386I113-V164 HydrophobicContact CG2-CG2 3.94Å; V160-V164 HydrophobicContact CG1-CG2 4.26Å; V160-V164 WeakPolarHBondContact O-CG2 3.31Å; V160-V164 PolarHBondContact O-N 3.2Å; Q162-V164 VanDerWaalsContact C-N 3.3Å; Q162-V164 PolarHBondContact O-N 3.23Å; V164-N166 HydrophobicContact CG1-CB 4.19Å; V164-L378 HydrophobicContact CG2-CD1 4.07Å; V164-A381 HydrophobicContact CB-CB 4.35Å; V164-A381 HydrophobicContact CG2-CB 3.87Å; V164-E382 HydrophobicContact CG2-CG 4.44Å; V164-K386 PolarHBondContact O-NZ 3.31Å
165G96.8Very high96.2Very high14 Ų1436.9 Ų36.914%0.14421%0.214CC..THydrogen-bonded Turntrans66.943.5-174.200000112D161 Q162 K386 P387D161-G165 WeakPolarHBondContact O-CA 3.41Å; D161-G165 PolarHBondContact O-N 3.23Å; Q162-G165 PolarHBondContact O-N 3.15Å; Q162-G165 VanDerWaalsContact O-N 3.12Å; G165-K386 WeakPolarHBondContact O-CD 3.48Å; G165-P387 VanDerWaalsContact O-CD 3.31Å; G165-P387 WeakPolarHBondContact O-CD 3.5Å
166N95.3Very high96.3Very high0 Ų038.3 Ų38.30%022%0.216CC..  trans-88.8179.3179.770.241.4000112.4D161 V164 D168 D169 A381 K384 K385 P387D161-N166 WeakPolarHBondContact CA-ND2 3.34Å; D161-N166 WeakPolarHBondContact CB-OD1 3.16Å; D161-N166 PolarHBondContact O-N 3.29Å; D161-N166 PolarHBondContact OD1-ND2 3.23Å; D161-N166 PolarHBondContact OD1-OD1 3.49Å; V164-N166 HydrophobicContact CG1-CB 4.19Å; N166-D168 PolarHBondContact O-N 2.85Å; N166-D168 PolarHBondContact OD1-N 3.21Å; N166-D169 VanDerWaalsContact O-CB 3.3Å; N166-D169 WeakPolarHBondContact O-CB 3.44Å; N166-D169 PolarHBondContact O-N 3.04Å; N166-A381 WeakPolarHBondContact ND2-CA 3.46Å; N166-A381 WeakPolarHBondContact ND2-CB 3.47Å; N166-A381 PolarHBondContact ND2-O 3.19Å; N166-K384 HydrophobicContact CB-CB 3.88Å; N166-K385 CarbonylContact C-O 3.5Å; N166-K385 WeakPolarHBondContact CA-O 3.46Å; N166-K385 WeakPolarHBondContact CB-O 3.35Å; N166-P387 WeakPolarHBondContact O-CG 3.45Å
167E91.6Very high96.3Very high76 Ų7637.4 Ų37.436%0.35521%0.211SC..THydrogen-bonded Turntrans-63.6-18.3-174.868.3-170.1139.500114.9K385 S429E167-K385 WeakPolarHBondContact CB-O 3.45Å; E167-K385 PolarHBondContact N-O 2.79Å; E167-K385 PolarHBondContact OE1-N 2.58Å; E167-S429 WeakPolarHBondContact OE2-CB 3.39Å
168D92.6Very high96.3Very high86 Ų8635.8 Ų35.846%0.4620%0.204SC..THydrogen-bonded Turntrans-92.6-3176.2-72.4-17.3000112.7D161 N166 T170 K384D161-D168 HydrophobicContact CB-CB 4.39Å; D161-D168 WeakPolarHBondContact OD2-CB 3.31Å; N166-D168 PolarHBondContact O-N 2.85Å; N166-D168 PolarHBondContact OD1-N 3.21Å; D168-T170 PolarHBondContact O-N 2.76Å; D168-K384 HydrophobicContact CB-CD 4.28Å; D168-K384 WeakPolarHBondContact OD2-CD 3.32Å; D168-K384 WeakPolarHBondContact OD2-CE 3.26Å; D168-K384 IonicContact OD2-NZ 3.19Å; D168-K384 PolarHBondContact OD2-NZ 3.13Å
169D95.2Very high96.4Very high5 Ų535 Ų353%0.02720%0.197CC..  trans-64.6117.8168.3176.323000110.1N166 G171 L172 G173N166-D169 VanDerWaalsContact O-CB 3.3Å; N166-D169 WeakPolarHBondContact O-CB 3.44Å; N166-D169 PolarHBondContact O-N 3.04Å; D169-G171 PolarHBondContact O-N 3.19Å; D169-G171 PolarHBondContact OD1-N 3.31Å; D169-L172 WeakPolarHBondContact O-CA 3.3Å; D169-L172 PolarHBondContact O-N 3.29Å; D169-L172 PolarHBondContact OD2-N 3.32Å; D169-G173 WeakPolarHBondContact OD2-CA 3.35Å; D169-G173 PolarHBondContact OD2-N 2.99Å
170T91.2Very high96.4Very high110 Ų11035.2 Ų35.268%0.67520%0.197SC*.THydrogen-bonded Turntrans-63.1-21.7175.363.30000113.3D168 L172D168-T170 PolarHBondContact O-N 2.76Å; T170-L172 VanDerWaalsContact C-N 3.25Å
171G94Very high96.3Very high31 Ų3135.7 Ų35.732%0.3220%0.203SC..THydrogen-bonded Turntrans-80.1-0.4169.800000114.3D169 G173 R174D169-G171 PolarHBondContact O-N 3.19Å; D169-G171 PolarHBondContact OD1-N 3.31Å; G171-G173 PolarHBondContact O-N 3.2Å; G171-R174 WeakPolarHBondContact O-CB 3.24Å; G171-R174 WeakPolarHBondContact O-CG 3.26Å; G171-R174 PolarHBondContact O-N 3.44Å
172L94.7Very high96.3Very high45 Ų4536.2 Ų36.224%0.23621%0.206CC..THydrogen-bonded Turntrans56.534179.6-56.9173.5000113.3D169 T170 R174 P387D169-L172 WeakPolarHBondContact O-CA 3.3Å; D169-L172 PolarHBondContact O-N 3.29Å; D169-L172 PolarHBondContact OD2-N 3.32Å; T170-L172 VanDerWaalsContact C-N 3.25Å; L172-R174 HydrophobicContact CB-CG 4.37Å; L172-R174 VanDerWaalsContact CD1-NH2 3.26Å; L172-R174 PolarHBondContact O-N 2.77Å; L172-P387 VanDerWaalsContact C-CG 3.48Å; L172-P387 WeakPolarHBondContact O-CG 3.39Å
173G95.2Very high96.2Very high36 Ų3645.4 Ų45.437%0.37125%0.246SC..THydrogen-bonded Turntrans65.220.317600000114D169 G171D169-G173 WeakPolarHBondContact OD2-CA 3.35Å; D169-G173 PolarHBondContact OD2-N 2.99Å; G171-G173 PolarHBondContact O-N 3.2Å
174R96.9Very high96.2Very high95 Ų9552.4 Ų52.436%0.35828%0.279SS..  trans-90-24.4-172.1-65.9169.1-176.7164.9-5114.3G171 L172 S391 T394 H395G171-R174 WeakPolarHBondContact O-CB 3.24Å; G171-R174 WeakPolarHBondContact O-CG 3.26Å; G171-R174 PolarHBondContact O-N 3.44Å; L172-R174 HydrophobicContact CB-CG 4.37Å; L172-R174 VanDerWaalsContact CD1-NH2 3.26Å; L172-R174 PolarHBondContact O-N 2.77Å; R174-S391 PolarHBondContact NH2-O 3.29Å; R174-T394 VanDerWaalsContact CZ-O 3.32Å; R174-T394 PolarHBondContact NH1-O 2.79Å; R174-T394 PolarHBondContact NH2-O 3.35Å; R174-T394 PolarHBondContact NH2-OG1 2.89Å; R174-H395 PolarHBondContact NH1-CD2 2.96Å
175Q97.9Very high96.2Very high85 Ų8553.6 Ų53.640%0.39728%0.283SS..SBendtrans-101.8158.8-178-68.5-84.279.500110.4H179 I190Q175-H179 HydrophobicContact CB-CB 3.7Å; Q175-H179 HydrophobicContact CG-CB 4.35Å; Q175-H179 PolarHBondContact NE2-ND1 3.19Å; Q175-I190 PolarHBondContact NE2-O 3.47Å
176M98.2Very high96.2Very high88 Ų8854.6 Ų54.643%0.43329%0.285SS..PPolyproline II helixtrans-59.2149.7171.2-169.4175.3-62.100110.6F115 Q162 H179F115-M176 HydrophobicContact CB-CG 4Å; F115-M176 HydrophobicContact CB-SD 4.2Å; F115-M176 HydrophobicContact CD1-CG 3.82Å; F115-M176 HydrophobicContact CD1-SD 3.57Å; F115-M176 VanDerWaalsContact CD1-SD 3.57Å; F115-M176 HydrophobicContact CD2-SD 4.26Å; F115-M176 HydrophobicContact CE1-SD 3.88Å; F115-M176 HydrophobicContact CG-CG 4.08Å; F115-M176 HydrophobicContact CG-SD 3.76Å; F115-M176 HydrophobicContact CZ-SD 4.36Å; Q162-M176 PolarHBondContact NE2-O 2.91Å; M176-H179 VanDerWaalsContact O-CB 3.27Å; M176-H179 WeakPolarHBondContact O-CB 3.42Å; M176-H179 PolarHBondContact O-N 3.49Å
177P98.4Very high96.4Very high7 Ų754.8 Ų54.85%0.04529%0.285CS..THydrogen-bonded Turntrans-48.9148.1169.1-30.737.3000112.3S114 F115 C163 H179S114-P177 WeakPolarHBondContact OG-CD 3.45Å; S114-P177 VanDerWaalsContact OG-CG 3.31Å; S114-P177 WeakPolarHBondContact OG-CG 3.24Å; F115-P177 HydrophobicContact CB-CB 4.4Å; F115-P177 HydrophobicContact CB-CG 4.29Å; F115-P177 WeakPolarHBondContact O-CB 3.37Å; C163-P177 HydrophobicContact CB-CB 4.33Å; C163-P177 WeakPolarHBondContact O-CG 3.43Å; P177-H179 PolarHBondContact O-N 2.9Å
178V98.2Very high96.7Very high6 Ų653.3 Ų53.34%0.03628%0.282CS..THydrogen-bonded Turntrans75.9-1.9-177.4-167.40000114Y116 Y143 Y180 I190Y116-V178 HydrophobicContact CD2-CG2 3.56Å; Y116-V178 HydrophobicContact CE2-CG2 3.76Å; Y116-V178 HydrophobicContact CG-CG2 4.3Å; Y143-V178 WeakPolarHBondContact O-CG1 3.12Å; V178-Y180 HydrophobicContact CB-CE2 4.26Å; V178-Y180 HydrophobicContact CG1-CD2 4.48Å; V178-Y180 HydrophobicContact CG1-CE2 3.9Å; V178-Y180 PolarHBondContact O-N 2.89Å; V178-I190 WeakPolarHBondContact O-CD1 3.4Å
179H98.5Very high97Very high20 Ų2053.2 Ų53.29%0.09328%0.284CS..  trans-84.160.4169.9-72.4-149000112Q175 M176 P177 I190 S192Q175-H179 HydrophobicContact CB-CB 3.7Å; Q175-H179 HydrophobicContact CG-CB 4.35Å; Q175-H179 PolarHBondContact NE2-ND1 3.19Å; M176-H179 VanDerWaalsContact O-CB 3.27Å; M176-H179 WeakPolarHBondContact O-CB 3.42Å; M176-H179 PolarHBondContact O-N 3.49Å; P177-H179 PolarHBondContact O-N 2.9Å; H179-I190 HydrophobicContact CB-CB 4.38Å; H179-I190 HydrophobicContact CB-CG2 4.45Å; H179-S192 PolarHBondContact CE1-N 3.48Å
180Y98.2Very high97.2Very high3 Ų353.2 Ų53.21%0.01228%0.284CS..  trans-68.5156-178.7-50.7-57.3000112.3L146 L149 L159 Q162 C163 V178 T189 I190L146-Y180 HydrophobicContact CD1-CE2 4.18Å; L149-Y180 VanDerWaalsContact CD1-CB 3.43Å; L149-Y180 HydrophobicContact CD1-CD2 3.93Å; L149-Y180 HydrophobicContact CD1-CG 3.88Å; L159-Y180 HydrophobicContact CD2-CE1 4.1Å; L159-Y180 WeakPolarHBondContact CD2-OH 3.34Å; L159-Y180 HydrophobicContact CG-CE1 3.86Å; Q162-Y180 HydrophobicContact CB-CD1 4.07Å; Q162-Y180 HydrophobicContact CB-CE1 4.15Å; Q162-Y180 HydrophobicContact CG-CD1 3.96Å; Q162-Y180 HydrophobicContact CG-CE1 4.33Å; C163-Y180 PolarHBondContact SG-OH 2.95Å; V178-Y180 HydrophobicContact CB-CE2 4.26Å; V178-Y180 HydrophobicContact CG1-CD2 4.48Å; V178-Y180 HydrophobicContact CG1-CE2 3.9Å; V178-Y180 PolarHBondContact O-N 2.89Å; Y180-T189 WeakPolarHBondContact O-CA 3.36Å; Y180-I190 PolarHBondContact O-N 2.6Å
181G97.6Very high97.5Very high11 Ų1150 Ų5011%0.11327%0.266CS..  trans-161.4143.8173.600000110.3
182S97.7Very high97.7Very high14 Ų1452.3 Ų52.310%0.09828%0.277CS..BIsolated β-bridgetrans-152.1112.8175.3-179.70000111.3E184 K185 N186 Y187S182-E184 VanDerWaalsContact C-N 3.3Å; S182-E184 PolarHBondContact O-N 2.74Å; S182-E184 PolarHBondContact OG-N 3.01Å; S182-K185 PolarHBondContact O-N 3.03Å; S182-K185 PolarHBondContact OG-N 2.97Å; S182-N186 PolarHBondContact O-N 3.43Å; S182-Y187 CarbonylContact C-O 3.57Å; S182-Y187 PolarHBondContact N-O 2.87Å; S182-Y187 PolarHBondContact O-N 3.38Å; S182-Y187 VanDerWaalsContact O-O 3.12Å
183K96.9Very high97.9Very high202 Ų20254.6 Ų54.688%0.87829%0.293SS*.THydrogen-bonded Turntrans-61.4-40.2172-175.8178.4179.3179.40111.6K185 N186K183-K185 VanDerWaalsContact C-N 3.33Å; K183-K185 PolarHBondContact O-N 2.78Å; K183-N186 PolarHBondContact O-N 2.92Å
184E96.8Very high98Very high150 Ų15055.5 Ų55.570%0.70129%0.289SS*.THydrogen-bonded Turntrans-62.8-41.1-179.9-171.2-160.2137.800111.5S182 N186S182-E184 VanDerWaalsContact C-N 3.3Å; S182-E184 PolarHBondContact O-N 2.74Å; S182-E184 PolarHBondContact OG-N 3.01Å; E184-N186 VanDerWaalsContact C-N 3.29Å; E184-N186 PolarHBondContact O-N 3Å
185K97.8Very high98.1Very high42 Ų4251 Ų5118%0.18327%0.272CS..THydrogen-bonded Turntrans-90.716.4-178.7-53.4-47.2-170.2-171.60113.3R152 Y154 S182 K183 Y187R152-K185 HydrophobicContact CB-CB 4.14Å; R152-K185 HydrophobicContact CB-CD 4.27Å; R152-K185 HydrophobicContact CB-CG 4.37Å; R152-K185 WeakPolarHBondContact CD-O 3.5Å; R152-K185 PolarHBondContact NH1-O 3.07Å; R152-K185 WeakPolarHBondContact O-CD 3.45Å; R152-K185 WeakPolarHBondContact O-CE 3.48Å; R152-K185 PolarHBondContact O-NZ 2.91Å; Y154-K185 HydrophobicContact CD2-CG 4.15Å; S182-K185 PolarHBondContact O-N 3.03Å; S182-K185 PolarHBondContact OG-N 2.97Å; K183-K185 VanDerWaalsContact C-N 3.33Å; K183-K185 PolarHBondContact O-N 2.78Å; K185-Y187 PolarHBondContact O-N 3.47Å
186N98.2Very high98.1Very high35 Ų3548.3 Ų48.319%0.18726%0.262CS..THydrogen-bonded Turntrans45.347.5-176.2-64.7-59.4000112.5D135 L138 I139 R152 S182 K183 E184D135-N186 PolarHBondContact O-ND2 3.12Å; L138-N186 HydrophobicContact CD1-CB 4.04Å; I139-N186 PolarHBondContact N-O 3.29Å; R152-N186 PolarHBondContact NH1-O 2.74Å; S182-N186 PolarHBondContact O-N 3.43Å; K183-N186 PolarHBondContact O-N 2.92Å; E184-N186 VanDerWaalsContact C-N 3.29Å; E184-N186 PolarHBondContact O-N 3Å
187Y98.6Very high98.2Very high4 Ų444.5 Ų44.52%0.01624%0.243CC..BIsolated β-bridgetrans-123.4109.7-179.3-168.4-75.6000109I139 A141 E145 P148 L149 S182 K185 I190I139-Y187 HydrophobicContact CB-CD2 4.08Å; I139-Y187 HydrophobicContact CG2-CD2 3.78Å; I139-Y187 HydrophobicContact CG2-CE2 3.88Å; A141-Y187 HydrophobicContact CB-CE1 3.77Å; A141-Y187 HydrophobicContact CB-CE2 4.11Å; A141-Y187 WeakPolarHBondContact CB-OH 3.49Å; E145-Y187 HydrophobicContact CB-CE2 4.36Å; E145-Y187 VanDerWaalsContact CB-OH 3.27Å; E145-Y187 WeakPolarHBondContact CB-OH 3.44Å; E145-Y187 WeakPolarHBondContact O-CE2 3.28Å; E145-Y187 PolarHBondContact O-OH 2.9Å; P148-Y187 HydrophobicContact CB-CD2 4.19Å; P148-Y187 HydrophobicContact CB-CE2 4Å; P148-Y187 HydrophobicContact CG-CE2 4.37Å; L149-Y187 HydrophobicContact CD1-CD1 4.45Å; L149-Y187 HydrophobicContact CD1-CE1 4.17Å; L149-Y187 HydrophobicContact CD1-CE2 4.33Å; L149-Y187 HydrophobicContact CD2-CD1 4.11Å; L149-Y187 HydrophobicContact CD2-CD2 3.88Å; L149-Y187 HydrophobicContact CD2-CE2 4.37Å; L149-Y187 HydrophobicContact CD2-CG 3.7Å; L149-Y187 HydrophobicContact CG-CD1 4.37Å; L149-Y187 HydrophobicContact CG-CD2 3.85Å; L149-Y187 HydrophobicContact CG-CE1 4.38Å; L149-Y187 HydrophobicContact CG-CE2 3.84Å; L149-Y187 HydrophobicContact CG-CG 4.09Å; S182-Y187 CarbonylContact C-O 3.57Å; S182-Y187 PolarHBondContact N-O 2.87Å; S182-Y187 PolarHBondContact O-N 3.38Å; S182-Y187 VanDerWaalsContact O-O 3.12Å; K185-Y187 PolarHBondContact O-N 3.47Å; Y187-I190 HydrophobicContact CE1-CD1 4.02Å; Y187-I190 HydrophobicContact CE1-CG1 4.1Å
188V98.6Very high98.2Very high45 Ų4544.2 Ų44.227%0.27324%0.241SC..PPolyproline II helixtrans-69.1136.6-176.4-179.40000109.9L138 I139 F140 I190L138-V188 HydrophobicContact CD1-CG2 3.82Å; L138-V188 HydrophobicContact CD2-CG2 3.98Å; L138-V188 HydrophobicContact CG-CG2 3.86Å; I139-V188 PolarHBondContact O-N 3.36Å; F140-V188 HydrophobicContact CD1-CB 4.02Å; F140-V188 HydrophobicContact CD1-CG1 4.06Å; F140-V188 HydrophobicContact CD1-CG2 3.97Å; F140-V188 HydrophobicContact CD2-CG2 4.36Å; F140-V188 HydrophobicContact CE1-CB 4.17Å; F140-V188 HydrophobicContact CE1-CG1 4.01Å; F140-V188 HydrophobicContact CE1-CG2 3.75Å; F140-V188 HydrophobicContact CE2-CG2 4.15Å; F140-V188 HydrophobicContact CG-CB 4.46Å; F140-V188 HydrophobicContact CG-CG2 4.28Å; F140-V188 HydrophobicContact CZ-CG2 3.84Å; V188-I190 PolarHBondContact O-N 2.54Å
189T98.6Very high98.2Very high84 Ų8445.9 Ų45.952%0.51525%0.252SS..PPolyproline II helixtrans-58.3128.7-178.5-53.40000111.4Y180Y180-T189 WeakPolarHBondContact O-CA 3.36Å
190I98.6Very high98.2Very high4 Ų449.9 Ų49.92%0.02127%0.271CS..PPolyproline II helixtrans-66.3142.9179.9-68.9162.8000111.5A141 Q142 Q175 V178 H179 Y180 Y187 V188A141-I190 HydrophobicContact CB-CD1 4.1Å; A141-I190 HydrophobicContact CB-CG1 3.82Å; Q142-I190 WeakPolarHBondContact O-CG2 3.36Å; Q175-I190 PolarHBondContact NE2-O 3.47Å; V178-I190 WeakPolarHBondContact O-CD1 3.4Å; H179-I190 HydrophobicContact CB-CB 4.38Å; H179-I190 HydrophobicContact CB-CG2 4.45Å; Y180-I190 PolarHBondContact O-N 2.6Å; Y187-I190 HydrophobicContact CE1-CD1 4.02Å; Y187-I190 HydrophobicContact CE1-CG1 4.1Å; V188-I190 PolarHBondContact O-N 2.54Å
191S98Very high98.3Very high44 Ų4449.7 Ų49.731%0.30827%0.27SS..  trans-122149.4168.557.50000111T193S191-T193 VanDerWaalsContact C-N 3.34Å; S191-T193 PolarHBondContact O-N 2.76Å
192S98Very high98.3Very high79 Ų7949.4 Ų49.455%0.55227%0.266SS*.SBendtrans-67.4-32.8-178.4-179.90000113.2H179 L194H179-S192 PolarHBondContact CE1-N 3.48Å; S192-L194 PolarHBondContact O-N 3.35Å
193T98.3Very high98.4Very high93 Ų9350.7 Ų50.757%0.57128%0.282SS*.SBendtrans-67.1116.4-176.7-45.40000110.9S191 T196S191-T193 VanDerWaalsContact C-N 3.34Å; S191-T193 PolarHBondContact O-N 2.76Å; T193-T196 HydrophobicContact CG2-CG2 3.51Å; T193-T196 PolarHBondContact O-OG1 2.91Å
194L98.3Very high98.4Very high55 Ų5542.4 Ų42.429%0.28825%0.249SC..THydrogen-bonded Turntrans-64.2150.3-174.3-59.5-178.8000112.3Q142 Y143 S192 T196 A225 E228Q142-L194 HydrophobicContact CG-CD2 4.15Å; Y143-L194 HydrophobicContact CD1-CD2 4.42Å; Y143-L194 HydrophobicContact CE1-CD2 3.65Å; S192-L194 PolarHBondContact O-N 3.35Å; L194-T196 PolarHBondContact O-N 3.09Å; L194-A225 HydrophobicContact CB-CB 4.13Å; L194-E228 HydrophobicContact CB-CG 4.18Å
195A98.6Very high98.5Very high0 Ų035.2 Ų35.20%022%0.216CC..THydrogen-bonded Turntrans60.6-13.3176.400000117.3Q197 M198 P199 E228 D230A195-Q197 VanDerWaalsContact CA-OE1 3.3Å; A195-Q197 PolarHBondContact O-N 2.73Å; A195-Q197 VanDerWaalsContact O-N 3.09Å; A195-M198 HydrophobicContact CB-CG 4.44Å; A195-M198 HydrophobicContact CB-SD 3.88Å; A195-M198 VanDerWaalsContact O-CB 3.24Å; A195-M198 WeakPolarHBondContact O-CB 3.33Å; A195-M198 WeakPolarHBondContact O-CG 3.48Å; A195-M198 PolarHBondContact O-N 2.87Å; A195-P199 VanDerWaalsContact O-CD 3.3Å; A195-P199 WeakPolarHBondContact O-CD 3.47Å; A195-E228 HydrophobicContact CB-CB 3.52Å; A195-E228 HydrophobicContact CB-CG 3.96Å; A195-D230 HydrophobicContact CB-CB 3.96Å
196T98.7Very high98.6Very high28 Ų2837.1 Ų37.117%0.17222%0.222CC..THydrogen-bonded Turntrans-55.5-30.7179.756.90000113.8T193 L194 M198 P199 Q200 D230T193-T196 HydrophobicContact CG2-CG2 3.51Å; T193-T196 PolarHBondContact O-OG1 2.91Å; L194-T196 PolarHBondContact O-N 3.09Å; T196-M198 VanDerWaalsContact C-N 3.27Å; T196-M198 PolarHBondContact O-N 3.16Å; T196-P199 WeakPolarHBondContact O-CD 3.39Å; T196-Q200 VanDerWaalsContact O-CD 3.24Å; T196-Q200 VanDerWaalsContact O-CG 3.26Å; T196-Q200 WeakPolarHBondContact O-CG 3.28Å; T196-Q200 PolarHBondContact O-NE2 2.88Å; T196-Q200 VanDerWaalsContact O-NE2 3.08Å; T196-D230 WeakPolarHBondContact CA-OD2 3.23Å
197Q98.7Very high98.6Very high9 Ų939.3 Ų39.34%0.04223%0.233CC..Hα-helixtrans-70.6-20.1176.781.9-72.84.400113.2F140 A195 Q200 A201 Y220F140-Q197 HydrophobicContact CB-CB 4.18Å; F140-Q197 HydrophobicContact CB-CG 4.06Å; F140-Q197 HydrophobicContact CD1-CB 4.19Å; A195-Q197 VanDerWaalsContact CA-OE1 3.3Å; A195-Q197 PolarHBondContact O-N 2.73Å; A195-Q197 VanDerWaalsContact O-N 3.09Å; Q197-Q200 PolarHBondContact O-N 2.83Å; Q197-A201 WeakPolarHBondContact O-CB 3.2Å; Q197-A201 PolarHBondContact O-N 2.94Å; Q197-Y220 PolarHBondContact NE2-O 2.75Å
198M98.8Very high98.5Very high0 Ų039.2 Ų39.20%023%0.233CC..Hα-helixtrans-66.1-56.4-176.9-59.1179.368.300112.6A195 T196 Q200 A201 V202 F221 C231 A234 F235 F247A195-M198 HydrophobicContact CB-CG 4.44Å; A195-M198 HydrophobicContact CB-SD 3.88Å; A195-M198 VanDerWaalsContact O-CB 3.24Å; A195-M198 WeakPolarHBondContact O-CB 3.33Å; A195-M198 WeakPolarHBondContact O-CG 3.48Å; A195-M198 PolarHBondContact O-N 2.87Å; T196-M198 VanDerWaalsContact C-N 3.27Å; T196-M198 PolarHBondContact O-N 3.16Å; M198-Q200 PolarHBondContact O-N 3.41Å; M198-A201 WeakPolarHBondContact O-CB 3.15Å; M198-A201 PolarHBondContact O-N 2.9Å; M198-V202 WeakPolarHBondContact O-CG2 3.46Å; M198-V202 PolarHBondContact O-N 2.84Å; M198-F221 HydrophobicContact CE-CD1 3.81Å; M198-F221 HydrophobicContact CE-CD2 3.98Å; M198-F221 HydrophobicContact CE-CE1 3.79Å; M198-F221 HydrophobicContact CE-CE2 3.91Å; M198-F221 HydrophobicContact CE-CG 3.93Å; M198-F221 HydrophobicContact CE-CZ 3.82Å; M198-F221 HydrophobicContact SD-CB 4.09Å; M198-F221 HydrophobicContact SD-CD1 4.18Å; M198-F221 HydrophobicContact SD-CD2 4.07Å; M198-F221 HydrophobicContact SD-CG 3.85Å; M198-C231 HydrophobicContact CE-CB 3.94Å; M198-C231 HydrophobicContact SD-CB 3.86Å; M198-A234 HydrophobicContact CB-CB 3.6Å; M198-F235 HydrophobicContact CE-CD1 4.32Å; M198-F235 HydrophobicContact CE-CE1 3.65Å; M198-F235 HydrophobicContact CE-CZ 4.13Å; M198-F247 HydrophobicContact CE-CD1 4.14Å; M198-F247 HydrophobicContact CE-CE1 4.39Å
199P98.8Very high98.4Very high42 Ų4240.8 Ų40.827%0.27324%0.236SC..Hα-helixtrans-66-28.1176.125.7-34.2000112.2A195 T196 V202 G203 D230 A234A195-P199 VanDerWaalsContact O-CD 3.3Å; A195-P199 WeakPolarHBondContact O-CD 3.47Å; T196-P199 WeakPolarHBondContact O-CD 3.39Å; P199-V202 WeakPolarHBondContact O-CB 3.22Å; P199-V202 PolarHBondContact O-N 3.13Å; P199-G203 PolarHBondContact O-N 3.29Å; P199-D230 HydrophobicContact CG-CB 4.12Å; P199-A234 HydrophobicContact CB-CB 4.47Å
200Q98.8Very high98.4Very high103 Ų10341.3 Ų41.348%0.48124%0.235SC..Hα-helixtrans-65-42173.8-63170.622.300111.8F140 T196 Q197 M198 V202 G203 S204F140-Q200 HydrophobicContact CD1-CB 4.4Å; F140-Q200 HydrophobicContact CE1-CB 3.92Å; T196-Q200 VanDerWaalsContact O-CD 3.24Å; T196-Q200 VanDerWaalsContact O-CG 3.26Å; T196-Q200 WeakPolarHBondContact O-CG 3.28Å; T196-Q200 PolarHBondContact O-NE2 2.88Å; T196-Q200 VanDerWaalsContact O-NE2 3.08Å; Q197-Q200 PolarHBondContact O-N 2.83Å; M198-Q200 PolarHBondContact O-N 3.41Å; Q200-V202 VanDerWaalsContact C-N 3.28Å; Q200-V202 PolarHBondContact O-N 2.88Å; Q200-G203 PolarHBondContact O-N 3.24Å; Q200-S204 PolarHBondContact O-N 3.39Å
201A98.8Very high98.3Very high0 Ų045.7 Ų45.70%026%0.259CS..Hα-helixtrans-60.6-39.1173.700000111.8F140 Q197 M198 S204 A205 C219 V245F140-A201 HydrophobicContact CB-CB 4.12Å; F140-A201 HydrophobicContact CD1-CB 4.22Å; F140-A201 HydrophobicContact CD2-CB 3.45Å; F140-A201 VanDerWaalsContact CD2-CB 3.45Å; F140-A201 VanDerWaalsContact CE2-CA 3.49Å; F140-A201 HydrophobicContact CE2-CB 3.8Å; F140-A201 HydrophobicContact CG-CB 3.67Å; F140-A201 HydrophobicContact CZ-CB 4.33Å; Q197-A201 WeakPolarHBondContact O-CB 3.2Å; Q197-A201 PolarHBondContact O-N 2.94Å; M198-A201 WeakPolarHBondContact O-CB 3.15Å; M198-A201 PolarHBondContact O-N 2.9Å; A201-S204 PolarHBondContact O-N 3.29Å; A201-A205 WeakPolarHBondContact O-CB 3.27Å; A201-A205 PolarHBondContact O-N 3.16Å; A201-C219 HydrophobicContact CB-CB 3.72Å; A201-V245 HydrophobicContact CB-CG2 4.43Å
202V98.9Very high98.3Very high4 Ų452.9 Ų52.92%0.02429%0.285CS..Hα-helixtrans-63.3-44174.3-1800000111.4M198 P199 Q200 S204 A205 Y206 A234 F237 A238 C243 F247M198-V202 WeakPolarHBondContact O-CG2 3.46Å; M198-V202 PolarHBondContact O-N 2.84Å; P199-V202 WeakPolarHBondContact O-CB 3.22Å; P199-V202 PolarHBondContact O-N 3.13Å; Q200-V202 VanDerWaalsContact C-N 3.28Å; Q200-V202 PolarHBondContact O-N 2.88Å; V202-S204 PolarHBondContact O-N 3.17Å; V202-A205 PolarHBondContact O-N 3.42Å; V202-Y206 WeakPolarHBondContact O-CB 3.47Å; V202-Y206 PolarHBondContact O-N 3.06Å; V202-A234 HydrophobicContact CG2-CB 4.07Å; V202-F237 HydrophobicContact CG1-CB 3.97Å; V202-A238 HydrophobicContact CG1-CB 4.24Å; V202-A238 HydrophobicContact CG2-CB 3.96Å; V202-C243 HydrophobicContact CG1-CB 4.33Å; V202-F247 HydrophobicContact CG2-CE1 4.12Å; V202-F247 HydrophobicContact CG2-CZ 3.57Å
203G98.6Very high98.2Very high42 Ų4253.3 Ų53.343%0.43328%0.278SS..Hα-helixtrans-60.8-42.4175.500000112.7P199 Q200 Y206 I207P199-G203 PolarHBondContact O-N 3.29Å; Q200-G203 PolarHBondContact O-N 3.24Å; G203-Y206 WeakPolarHBondContact O-CB 3.46Å; G203-Y206 PolarHBondContact O-N 2.98Å; G203-I207 PolarHBondContact O-N 3.06Å
204S98.5Very high98.1Very high27 Ų2754.4 Ų54.419%0.18928%0.28CS..Hα-helixtrans-66.4-42.1176.4-168.70000113L138 Q200 A201 V202 Y206 I207 S208L138-S204 WeakPolarHBondContact CD2-OG 3.38Å; Q200-S204 PolarHBondContact O-N 3.39Å; A201-S204 PolarHBondContact O-N 3.29Å; V202-S204 PolarHBondContact O-N 3.17Å; S204-Y206 VanDerWaalsContact C-N 3.31Å; S204-Y206 PolarHBondContact O-N 3.21Å; S204-I207 WeakPolarHBondContact O-CG2 3.37Å; S204-I207 PolarHBondContact O-N 2.89Å; S204-S208 PolarHBondContact O-N 3.2Å; S204-S208 PolarHBondContact O-OG 3.2Å
205A98.7Very high98Very high0 Ų054.8 Ų54.80%028%0.278CS..Hα-helixtrans-63-39.9173.200000111.3A201 V202 S208 K209 S217 C243 P244 V245A201-A205 WeakPolarHBondContact O-CB 3.27Å; A201-A205 PolarHBondContact O-N 3.16Å; V202-A205 PolarHBondContact O-N 3.42Å; A205-S208 WeakPolarHBondContact O-CB 3.46Å; A205-S208 PolarHBondContact O-N 3.25Å; A205-K209 PolarHBondContact O-N 3.05Å; A205-S217 PolarHBondContact N-OG 3.23Å; A205-C243 HydrophobicContact CB-CB 3.97Å; A205-P244 HydrophobicContact CB-CG 4.07Å; A205-P244 WeakPolarHBondContact CB-O 3.5Å; A205-P244 VanDerWaalsContact O-CD 3.28Å; A205-P244 WeakPolarHBondContact O-CD 3.46Å; A205-P244 VanDerWaalsContact O-CG 3.29Å; A205-P244 WeakPolarHBondContact O-CG 3.06Å; A205-V245 HydrophobicContact CB-CB 3.88Å
206Y98.6Very high98Very high81 Ų8154.8 Ų54.832%0.31828%0.278SS..Hα-helixtrans-62.6-45.8178.6-172-106.5000112.1V202 G203 S204 K209 L210 L241V202-Y206 WeakPolarHBondContact O-CB 3.47Å; V202-Y206 PolarHBondContact O-N 3.06Å; G203-Y206 WeakPolarHBondContact O-CB 3.46Å; G203-Y206 PolarHBondContact O-N 2.98Å; S204-Y206 VanDerWaalsContact C-N 3.31Å; S204-Y206 PolarHBondContact O-N 3.21Å; Y206-K209 WeakPolarHBondContact O-CB 3.45Å; Y206-K209 PolarHBondContact O-N 3.22Å; Y206-L210 HydrophobicContact CD1-CD1 3.9Å; Y206-L210 HydrophobicContact CD1-CG 4.29Å; Y206-L210 HydrophobicContact CE1-CD1 3.53Å; Y206-L210 HydrophobicContact CE1-CD2 4.41Å; Y206-L210 HydrophobicContact CE1-CG 4.03Å; Y206-L210 WeakPolarHBondContact O-CG 3.39Å; Y206-L210 PolarHBondContact O-N 2.99Å; Y206-L241 HydrophobicContact CD2-CB 3.8Å; Y206-L241 HydrophobicContact CD2-CD1 4.07Å; Y206-L241 HydrophobicContact CD2-CG 4.4Å; Y206-L241 HydrophobicContact CE2-CB 3.84Å; Y206-L241 HydrophobicContact CE2-CD1 4.16Å; Y206-L241 HydrophobicContact CE2-CD2 3.99Å; Y206-L241 HydrophobicContact CE2-CG 4.23Å
207I98Very high98Very high81 Ų8153.4 Ų53.442%0.41527%0.269SS..Hα-helixtrans-66.9-36176-169.160.3000112G203 S204 K209 L210 N211G203-I207 PolarHBondContact O-N 3.06Å; S204-I207 WeakPolarHBondContact O-CG2 3.37Å; S204-I207 PolarHBondContact O-N 2.89Å; I207-K209 VanDerWaalsContact C-N 3.3Å; I207-K209 PolarHBondContact O-N 2.92Å; I207-L210 HydrophobicContact CD1-CB 4.43Å; I207-L210 HydrophobicContact CD1-CD1 4.33Å; I207-L210 PolarHBondContact O-N 3.43Å; I207-N211 WeakPolarHBondContact O-CB 3.48Å; I207-N211 PolarHBondContact O-N 3.43Å; I207-N211 PolarHBondContact O-ND2 2.9Å
208S97Very high98Very high3 Ų353 Ų532%0.02127%0.267CS..Hα-helixtrans-59.3-43173.9-57.30000111.2S204 A205 N211 K212 Q213S204-S208 PolarHBondContact O-N 3.2Å; S204-S208 PolarHBondContact O-OG 3.2Å; A205-S208 WeakPolarHBondContact O-CB 3.46Å; A205-S208 PolarHBondContact O-N 3.25Å; S208-N211 CarbonylContact O-C 3.42Å; S208-N211 PolarHBondContact O-N 3.34Å; S208-K212 PolarHBondContact O-N 3.43Å; S208-K212 VanDerWaalsContact O-N 3.16Å; S208-Q213 PolarHBondContact O-N 3.31Å
209K97.7Very high98.1Very high78 Ų7853 Ų5334%0.33927%0.267SS..Hα-helixtrans-63.1-47.9174.3-173.5-16968.3168.70112.5A205 Y206 I207 N211 K212 L241 R242 P244A205-K209 PolarHBondContact O-N 3.05Å; Y206-K209 WeakPolarHBondContact O-CB 3.45Å; Y206-K209 PolarHBondContact O-N 3.22Å; I207-K209 VanDerWaalsContact C-N 3.3Å; I207-K209 PolarHBondContact O-N 2.92Å; K209-N211 PolarHBondContact O-N 3.49Å; K209-K212 PolarHBondContact O-N 2.64Å; K209-L241 PolarHBondContact NZ-O 3.11Å; K209-R242 WeakPolarHBondContact CD-O 3.36Å; K209-P244 HydrophobicContact CB-CG 4.1Å
210L97.8Very high98.1Very high95 Ų9551 Ų5150%0.49725%0.254SS..Hα-helixtrans-59.4-37.7178.6-71.4-179.1000111.8Y206 I207 K212Y206-L210 HydrophobicContact CD1-CD1 3.9Å; Y206-L210 HydrophobicContact CD1-CG 4.29Å; Y206-L210 HydrophobicContact CE1-CD1 3.53Å; Y206-L210 HydrophobicContact CE1-CD2 4.41Å; Y206-L210 HydrophobicContact CE1-CG 4.03Å; Y206-L210 WeakPolarHBondContact O-CG 3.39Å; Y206-L210 PolarHBondContact O-N 2.99Å; I207-L210 HydrophobicContact CD1-CB 4.43Å; I207-L210 HydrophobicContact CD1-CD1 4.33Å; I207-L210 PolarHBondContact O-N 3.43Å; L210-K212 PolarHBondContact O-N 3.48Å
211N97.5Very high98.1Very high96 Ų9646.1 Ų46.151%0.51323%0.232SC..THydrogen-bonded Turntrans-82.24176.8-68.1-23.1000113.9I207 S208 K209 Q213I207-N211 WeakPolarHBondContact O-CB 3.48Å; I207-N211 PolarHBondContact O-N 3.43Å; I207-N211 PolarHBondContact O-ND2 2.9Å; S208-N211 CarbonylContact O-C 3.42Å; S208-N211 PolarHBondContact O-N 3.34Å; K209-N211 PolarHBondContact O-N 3.49Å; N211-Q213 HydrophobicContact CB-CG 3.94Å; N211-Q213 PolarHBondContact O-N 2.98Å
212K96.4Very high98Very high195 Ų19546.4 Ų46.485%0.84823%0.234SC*.THydrogen-bonded Turntrans53.238.6-178.8-55.3179.7-178.5178.70113.3S208 K209 L210S208-K212 PolarHBondContact O-N 3.43Å; S208-K212 VanDerWaalsContact O-N 3.16Å; K209-K212 PolarHBondContact O-N 2.64Å; L210-K212 PolarHBondContact O-N 3.48Å
213Q96.3Very high98Very high88 Ų8846.3 Ų46.341%0.41123%0.234SC..  trans-83137.4178-64.8177.2-33.400110.3S208 N211 R215S208-Q213 PolarHBondContact O-N 3.31Å; N211-Q213 HydrophobicContact CB-CG 3.94Å; N211-Q213 PolarHBondContact O-N 2.98Å; Q213-R215 HydrophobicContact CB-CB 4.13Å; Q213-R215 PolarHBondContact O-N 3.4Å
214D96.4Very high98Very high115 Ų11545 Ų4562%0.61522%0.221SC*.SBendtrans-78.463170.3-175.324.6000110.5R299 L303D214-R299 PolarHBondContact O-NH2 3.47Å; D214-R299 IonicContact OD1-NH2 2.74Å; D214-L303 WeakPolarHBondContact OD1-CD1 3.36Å; D214-L303 VanDerWaalsContact OD1-CD2 3.31Å; D214-L303 WeakPolarHBondContact OD1-CD2 3.41Å
215R97Very high98Very high63 Ų6343.8 Ų43.824%0.23821%0.212CC..  trans-141.5134.3-171.7-178.5-175-73.8-152.3-13110.1E136 Q213E136-R215 VanDerWaalsContact O-CD 3.28Å; E136-R215 WeakPolarHBondContact O-CD 3.46Å; E136-R215 WeakPolarHBondContact O-CG 3.47Å; E136-R215 PolarHBondContact O-NE 2.92Å; E136-R215 PolarHBondContact O-NH2 3.31Å; Q213-R215 HydrophobicContact CB-CB 4.13Å; Q213-R215 PolarHBondContact O-N 3.4Å
216V98.7Very high98Very high0 Ų044 Ų440%021%0.213CC..  trans-105.4159170.1-56.90000111.2L133 D137 L138 P244 I246 R299 A302 L303L133-V216 HydrophobicContact CD2-CG2 4.1Å; D137-V216 WeakPolarHBondContact CA-O 3.5Å; D137-V216 HydrophobicContact CB-CG2 4.03Å; D137-V216 WeakPolarHBondContact OD1-CG2 3.34Å; D137-V216 PolarHBondContact OD1-N 2.89Å; L138-V216 PolarHBondContact N-O 3.18Å; V216-P244 VanDerWaalsContact CA-O 3.3Å; V216-P244 WeakPolarHBondContact CA-O 3.4Å; V216-P244 WeakPolarHBondContact CB-O 3.13Å; V216-P244 HydrophobicContact CG1-CB 4.29Å; V216-I246 HydrophobicContact CG2-CD1 4.11Å; V216-R299 HydrophobicContact CG1-CG 4Å; V216-R299 HydrophobicContact CG2-CG 3.96Å; V216-A302 HydrophobicContact CG1-CB 3.88Å; V216-L303 HydrophobicContact CG1-CD1 4.48Å; V216-L303 HydrophobicContact CG1-CD2 3.74Å; V216-L303 HydrophobicContact CG1-CG 3.68Å
217S98.8Very high98Very high0 Ų042.8 Ų42.80%022%0.217CC..EExtended strand (participates in β ladder)trans-101.2127.5160.5-60.70000109.2L138 A205 P244 V245 I246L138-S217 CarbonylContact O-C 3.59Å; L138-S217 VanDerWaalsContact O-CA 3.31Å; L138-S217 WeakPolarHBondContact O-CA 3.43Å; A205-S217 PolarHBondContact N-OG 3.23Å; S217-P244 PolarHBondContact N-O 3.23Å; S217-V245 CarbonylContact O-C 3.6Å; S217-V245 VanDerWaalsContact O-CA 3.29Å; S217-V245 WeakPolarHBondContact O-CA 3.19Å; S217-V245 WeakPolarHBondContact O-CG2 3.46Å; S217-I246 PolarHBondContact O-N 2.92Å
218L98.8Very high98Very high0 Ų043.4 Ų43.40%022%0.218CC..EExtended strand (participates in β ladder)trans-102.6127.3169-172.4148.3000109.1L133 L138 I139 F140 Y220 I246 F248 V295L133-L218 HydrophobicContact CD1-CB 3.91Å; L133-L218 HydrophobicContact CD1-CD1 3.95Å; L133-L218 HydrophobicContact CD1-CG 4.41Å; L133-L218 HydrophobicContact CD2-CB 4.38Å; L133-L218 HydrophobicContact CD2-CD1 4.06Å; L133-L218 HydrophobicContact CG-CD1 4.28Å; L138-L218 PolarHBondContact O-N 3.06Å; I139-L218 WeakPolarHBondContact CA-O 3.32Å; F140-L218 PolarHBondContact N-O 3.43Å; L218-Y220 HydrophobicContact CD2-CD1 4.02Å; L218-Y220 HydrophobicContact CD2-CD2 3.44Å; L218-Y220 VanDerWaalsContact CD2-CD2 3.44Å; L218-Y220 HydrophobicContact CD2-CE1 3.7Å; L218-Y220 HydrophobicContact CD2-CE2 3.11Å; L218-Y220 HydrophobicContact CD2-CG 3.9Å; L218-I246 WeakPolarHBondContact CA-O 3.27Å; L218-I246 HydrophobicContact CD1-CB 4.36Å; L218-I246 HydrophobicContact CD1-CD1 4.48Å; L218-I246 HydrophobicContact CD1-CG2 4.22Å; L218-I246 HydrophobicContact CG-CB 4.29Å; L218-I246 HydrophobicContact CG-CG2 4.46Å; L218-F248 HydrophobicContact CD2-CB 4.14Å; L218-F248 HydrophobicContact CG-CB 4.45Å; L218-V295 HydrophobicContact CD1-CG1 3.92Å
219C98.9Very high98.1Very high0 Ų045.9 Ų45.90%024%0.244CC..EExtended strand (participates in β ladder)trans-118.6112.5-177.8-176.40000110.8F140 A201 I246 F247 F248F140-C219 HydrophobicContact CB-CB 4.33Å; F140-C219 WeakPolarHBondContact O-CA 3.46Å; A201-C219 HydrophobicContact CB-CB 3.72Å; C219-I246 PolarHBondContact N-O 3.47Å; C219-F247 HydrophobicContact CB-CD1 4.15Å; C219-F248 PolarHBondContact O-N 2.95Å
220Y98.9Very high98.1Very high0 Ų045.1 Ų45.10%024%0.244CC..EExtended strand (participates in β ladder)trans-84.8145.4173.1-61.6-87.1000111.8S129 I139 F140 E145 P148 Q197 L218 F248S129-Y220 WeakPolarHBondContact CB-OH 3.41Å; S129-Y220 WeakPolarHBondContact OG-CE1 3.33Å; S129-Y220 PolarHBondContact OG-OH 3.24Å; I139-Y220 HydrophobicContact CG2-CD2 3.93Å; I139-Y220 HydrophobicContact CG2-CE2 3.64Å; F140-Y220 PolarHBondContact O-N 2.93Å; E145-Y220 HydrophobicContact CB-CD2 4.31Å; E145-Y220 HydrophobicContact CG-CD1 3.92Å; E145-Y220 HydrophobicContact CG-CD2 3.38Å; E145-Y220 HydrophobicContact CG-CE1 4.45Å; E145-Y220 HydrophobicContact CG-CE2 3.93Å; E145-Y220 HydrophobicContact CG-CG 3.35Å; E145-Y220 WeakPolarHBondContact OE1-CB 3.16Å; P148-Y220 HydrophobicContact CG-CE2 3.91Å; Q197-Y220 PolarHBondContact NE2-O 2.75Å; L218-Y220 HydrophobicContact CD2-CD1 4.02Å; L218-Y220 HydrophobicContact CD2-CD2 3.44Å; L218-Y220 VanDerWaalsContact CD2-CD2 3.44Å; L218-Y220 HydrophobicContact CD2-CE1 3.7Å; L218-Y220 HydrophobicContact CD2-CE2 3.11Å; L218-Y220 HydrophobicContact CD2-CG 3.9Å; Y220-F248 WeakPolarHBondContact CA-O 3.35Å; Y220-F248 HydrophobicContact CD1-CB 3.94Å; Y220-F248 AromaticContact CD1-CD1 3.66Å; Y220-F248 HydrophobicContact CD1-CD1 3.66Å; Y220-F248 HydrophobicContact CD1-CE1 4.45Å; Y220-F248 AromaticContact CD1-CG 3.97Å; Y220-F248 HydrophobicContact CD1-CG 3.97Å; Y220-F248 HydrophobicContact CE1-CB 4.24Å; Y220-F248 AromaticContact CE1-CD1 3.82Å; Y220-F248 HydrophobicContact CE1-CD1 3.82Å; Y220-F248 HydrophobicContact CE1-CE1 4.33Å; Y220-F248 AromaticContact CE1-CG 3.97Å; Y220-F248 HydrophobicContact CE1-CG 3.97Å
221F98.8Very high98.2Very high0 Ų040.7 Ų40.70%022%0.221CC..EExtended strand (participates in β ladder)trans-161.6156.2171.959.1-74.4000110M198 A225 F235 F247 F248 C249 R250 V269 L309M198-F221 HydrophobicContact CE-CD1 3.81Å; M198-F221 HydrophobicContact CE-CD2 3.98Å; M198-F221 HydrophobicContact CE-CE1 3.79Å; M198-F221 HydrophobicContact CE-CE2 3.91Å; M198-F221 HydrophobicContact CE-CG 3.93Å; M198-F221 HydrophobicContact CE-CZ 3.82Å; M198-F221 HydrophobicContact SD-CB 4.09Å; M198-F221 HydrophobicContact SD-CD1 4.18Å; M198-F221 HydrophobicContact SD-CD2 4.07Å; M198-F221 HydrophobicContact SD-CG 3.85Å; F221-A225 HydrophobicContact CB-CB 4.29Å; F221-F235 HydrophobicContact CE2-CZ 4.24Å; F221-F235 HydrophobicContact CZ-CE1 4.1Å; F221-F235 AromaticContact CZ-CZ 3.84Å; F221-F235 HydrophobicContact CZ-CZ 3.84Å; F221-F247 HydrophobicContact CE1-CB 3.77Å; F221-F247 HydrophobicContact CE1-CD1 4.35Å; F221-F247 HydrophobicContact CZ-CB 4.23Å; F221-F248 PolarHBondContact N-O 2.91Å; F221-F248 VanDerWaalsContact N-O 3.16Å; F221-C249 HydrophobicContact CD2-CB 4.3Å; F221-C249 HydrophobicContact CE1-CB 4.15Å; F221-C249 HydrophobicContact CE2-CB 3.64Å; F221-C249 HydrophobicContact CZ-CB 3.54Å; F221-C249 CarbonylContact O-C 3.49Å; F221-C249 VanDerWaalsContact O-CA 3.32Å; F221-C249 WeakPolarHBondContact O-CA 3.46Å; F221-R250 PolarHBondContact O-N 3.06Å; F221-V269 HydrophobicContact CE2-CG1 4.01Å; F221-V269 HydrophobicContact CZ-CG1 4.34Å; F221-L309 HydrophobicContact CZ-CD1 3.92Å
222G98.6Very high98.2Very high6 Ų641 Ų416%0.06222%0.219CC..EExtended strand (participates in β ladder)trans-87.7165.717500000113G224 A225 S226 R250G222-G224 VanDerWaalsContact C-N 3.26Å; G222-G224 PolarHBondContact O-N 3.42Å; G222-A225 PolarHBondContact O-N 3.21Å; G222-A225 VanDerWaalsContact O-N 3.13Å; G222-S226 PolarHBondContact O-N 2.89Å; G222-S226 VanDerWaalsContact O-N 3.17Å; G222-R250 WeakPolarHBondContact CA-O 3.35Å
223D98.4Very high98.3Very high2 Ų233.4 Ų33.41%0.01119%0.192CC..THydrogen-bonded Turntrans-52.9-41.9173.353.6-81.2000112.3S226 R250 N251 N252 V260 Y264D223-S226 VanDerWaalsContact O-CB 3.26Å; D223-S226 WeakPolarHBondContact O-CB 3.41Å; D223-S226 PolarHBondContact O-N 3.11Å; D223-S226 PolarHBondContact O-OG 2.92Å; D223-R250 PolarHBondContact N-O 3.25Å; D223-N251 HydrophobicContact CB-CB 4.26Å; D223-N252 PolarHBondContact OD1-N 2.98Å; D223-N252 VanDerWaalsContact OD1-N 3.16Å; D223-N252 PolarHBondContact OD1-OD1 3.43Å; D223-V260 HydrophobicContact CB-CG1 4.37Å; D223-Y264 HydrophobicContact CB-CE1 4.44Å
224G98.2Very high98.5Very high15 Ų1529.2 Ų29.216%0.15517%0.173CC..G310 helixtrans-65.8-39.9176.400000114.9G222 S226 S227 Q263G222-G224 VanDerWaalsContact C-N 3.26Å; G222-G224 PolarHBondContact O-N 3.42Å; G224-S226 PolarHBondContact O-N 3.01Å; G224-S227 WeakPolarHBondContact O-CB 3.45Å; G224-S227 PolarHBondContact O-N 3.17Å; G224-S227 VanDerWaalsContact O-N 3.15Å; G224-Q263 VanDerWaalsContact CA-NE2 3.28Å
225A98.5Very high98.6Very high1 Ų123.8 Ų23.81%0.00814%0.143CC..G310 helixtrans-67.7-19.2176.400000112.2L194 F221 G222 S227 E228L194-A225 HydrophobicContact CB-CB 4.13Å; F221-A225 HydrophobicContact CB-CB 4.29Å; G222-A225 PolarHBondContact O-N 3.21Å; G222-A225 VanDerWaalsContact O-N 3.13Å; A225-S227 PolarHBondContact O-N 3.13Å; A225-E228 WeakPolarHBondContact O-CB 3.38Å; A225-E228 PolarHBondContact O-N 2.88Å
226S98.4Very high98.7Very high4 Ų423.9 Ų23.93%0.02815%0.149CC..G310 helixtrans-66-16.9174.884.20000113.4G222 D223 G224 C231 V269 R272G222-S226 PolarHBondContact O-N 2.89Å; G222-S226 VanDerWaalsContact O-N 3.17Å; D223-S226 VanDerWaalsContact O-CB 3.26Å; D223-S226 WeakPolarHBondContact O-CB 3.41Å; D223-S226 PolarHBondContact O-N 3.11Å; D223-S226 PolarHBondContact O-OG 2.92Å; G224-S226 PolarHBondContact O-N 3.01Å; S226-C231 WeakPolarHBondContact O-CB 3.47Å; S226-C231 PolarHBondContact O-SG 3.27Å; S226-V269 WeakPolarHBondContact OG-CG2 3.4Å; S226-R272 PolarHBondContact O-NH1 3.19Å; S226-R272 PolarHBondContact OG-NH1 3.2Å; S226-R272 PolarHBondContact OG-NH2 3.14Å
227S98.4Very high98.7Very high57 Ų5729.6 Ų29.640%0.39917%0.174SC..G310 helixtrans-84.5-9.9177.7-620000113.5G224 A225 Q263G224-S227 WeakPolarHBondContact O-CB 3.45Å; G224-S227 PolarHBondContact O-N 3.17Å; G224-S227 VanDerWaalsContact O-N 3.15Å; A225-S227 PolarHBondContact O-N 3.13Å; S227-Q263 PolarHBondContact OG-OE1 3.1Å
228E98.7Very high98.7Very high94 Ų9429.6 Ų29.644%0.43917%0.174SC..SBendtrans-72.5148.8176.3-66-71.9-172.700111.8L194 A195 A225 D230 C231L194-E228 HydrophobicContact CB-CG 4.18Å; A195-E228 HydrophobicContact CB-CB 3.52Å; A195-E228 HydrophobicContact CB-CG 3.96Å; A225-E228 WeakPolarHBondContact O-CB 3.38Å; A225-E228 PolarHBondContact O-N 2.88Å; E228-D230 PolarHBondContact O-N 3.41Å; E228-C231 VanDerWaalsContact O-CB 3.24Å; E228-C231 WeakPolarHBondContact O-CB 3.5Å; E228-C231 PolarHBondContact O-N 3.32Å
229G98.6Very high98.6Very high55 Ų5531 Ų3157%0.56718%0.184SC*.Hα-helixtrans-59.8-30.4-179.700000114.1C231 H232 A233G229-C231 PolarHBondContact O-N 3.3Å; G229-H232 WeakPolarHBondContact O-CB 3.4Å; G229-H232 PolarHBondContact O-N 3.5Å; G229-A233 PolarHBondContact O-N 3.29Å; G229-A233 VanDerWaalsContact O-N 3.09Å
230D98.7Very high98.5Very high62 Ų6235.5 Ų35.533%0.33221%0.211SC..Hα-helixtrans-64.9-27.6177.3-80.5-13.4000112.8A195 T196 P199 E228 A233 A234A195-D230 HydrophobicContact CB-CB 3.96Å; T196-D230 WeakPolarHBondContact CA-OD2 3.23Å; P199-D230 HydrophobicContact CG-CB 4.12Å; E228-D230 PolarHBondContact O-N 3.41Å; D230-A233 PolarHBondContact O-N 3.17Å; D230-A234 VanDerWaalsContact O-CB 3.25Å; D230-A234 WeakPolarHBondContact O-CB 3.27Å; D230-A234 PolarHBondContact O-N 3.34Å
231C98.7Very high98.5Very high2 Ų238.2 Ų38.21%0.01423%0.225CC..Hα-helixtrans-63.5-47.8172.8177.30000110.9M198 S226 E228 G229 A233 A234 F235M198-C231 HydrophobicContact CE-CB 3.94Å; M198-C231 HydrophobicContact SD-CB 3.86Å; S226-C231 WeakPolarHBondContact O-CB 3.47Å; S226-C231 PolarHBondContact O-SG 3.27Å; E228-C231 VanDerWaalsContact O-CB 3.24Å; E228-C231 WeakPolarHBondContact O-CB 3.5Å; E228-C231 PolarHBondContact O-N 3.32Å; G229-C231 PolarHBondContact O-N 3.3Å; C231-A233 PolarHBondContact O-N 3.49Å; C231-A234 PolarHBondContact O-N 2.99Å; C231-F235 WeakPolarHBondContact O-CG 3.49Å; C231-F235 PolarHBondContact O-N 2.69Å; C231-F235 VanDerWaalsContact SG-CE2 3.53Å; C231-F235 VanDerWaalsContact SG-CZ 3.58Å
232H98.6Very high98.4Very high103 Ų10345.3 Ų45.348%0.47725%0.252SS..Hα-helixtrans-59.3-46.8175.8174.476.7000111.6G229 A234 N236 Y276G229-H232 WeakPolarHBondContact O-CB 3.4Å; G229-H232 PolarHBondContact O-N 3.5Å; H232-A234 PolarHBondContact O-N 3.11Å; H232-N236 PolarHBondContact O-N 2.66Å; H232-Y276 AromaticContact CE1-CE1 3.77Å; H232-Y276 AromaticContact ND1-CE1 3.51Å; H232-Y276 AromaticContact ND1-CZ 3.51Å; H232-Y276 PolarHBondContact ND1-OH 3.27Å
233A98.7Very high98.4Very high34 Ų3445 Ų4528%0.28125%0.249SC..Hα-helixtrans-59.3-47.9177.200000111.6G229 D230 C231 N236 F237G229-A233 PolarHBondContact O-N 3.29Å; G229-A233 VanDerWaalsContact O-N 3.09Å; D230-A233 PolarHBondContact O-N 3.17Å; C231-A233 PolarHBondContact O-N 3.49Å; A233-N236 PolarHBondContact O-N 2.68Å; A233-F237 WeakPolarHBondContact O-CB 3.29Å; A233-F237 VanDerWaalsContact O-CD2 3.27Å; A233-F237 WeakPolarHBondContact O-CD2 3.42Å; A233-F237 PolarHBondContact O-N 3.49Å
234A98.8Very high98.4Very high0 Ų045.2 Ų45.20%025%0.251CS..Hα-helixtrans-61-48.2-179.500000112.7M198 P199 V202 D230 C231 H232 N236 F237 A238 F247M198-A234 HydrophobicContact CB-CB 3.6Å; P199-A234 HydrophobicContact CB-CB 4.47Å; V202-A234 HydrophobicContact CG2-CB 4.07Å; D230-A234 VanDerWaalsContact O-CB 3.25Å; D230-A234 WeakPolarHBondContact O-CB 3.27Å; D230-A234 PolarHBondContact O-N 3.34Å; C231-A234 PolarHBondContact O-N 2.99Å; H232-A234 PolarHBondContact O-N 3.11Å; A234-N236 PolarHBondContact O-N 2.87Å; A234-F237 PolarHBondContact O-N 2.79Å; A234-A238 VanDerWaalsContact O-CB 3.23Å; A234-A238 WeakPolarHBondContact O-CB 3.47Å; A234-A238 PolarHBondContact O-N 3.45Å; A234-F247 HydrophobicContact CB-CE1 4.01Å; A234-F247 HydrophobicContact CB-CZ 4.05Å
235F98.8Very high98.4Very high1 Ų144.5 Ų44.50%0.00424%0.243CC..Hα-helixtrans-61.3-45.5-179.4-71.2-6.8000112M198 F221 C231 S239 F247 V269 Y276 L278 L309M198-F235 HydrophobicContact CE-CD1 4.32Å; M198-F235 HydrophobicContact CE-CE1 3.65Å; M198-F235 HydrophobicContact CE-CZ 4.13Å; F221-F235 HydrophobicContact CE2-CZ 4.24Å; F221-F235 HydrophobicContact CZ-CE1 4.1Å; F221-F235 AromaticContact CZ-CZ 3.84Å; F221-F235 HydrophobicContact CZ-CZ 3.84Å; C231-F235 WeakPolarHBondContact O-CG 3.49Å; C231-F235 PolarHBondContact O-N 2.69Å; C231-F235 VanDerWaalsContact SG-CE2 3.53Å; C231-F235 VanDerWaalsContact SG-CZ 3.58Å; F235-S239 PolarHBondContact O-N 3.06Å; F235-F247 HydrophobicContact CD1-CD1 4.28Å; F235-F247 AromaticContact CD1-CD2 3.81Å; F235-F247 HydrophobicContact CD1-CD2 3.81Å; F235-F247 HydrophobicContact CD1-CE1 4.27Å; F235-F247 AromaticContact CD1-CE2 3.77Å; F235-F247 HydrophobicContact CD1-CE2 3.77Å; F235-F247 HydrophobicContact CD1-CG 4.05Å; F235-F247 HydrophobicContact CD1-CZ 4Å; F235-F247 HydrophobicContact CE1-CB 4.02Å; F235-F247 AromaticContact CE1-CD1 3.96Å; F235-F247 HydrophobicContact CE1-CD1 3.96Å; F235-F247 AromaticContact CE1-CD2 3.86Å; F235-F247 HydrophobicContact CE1-CD2 3.86Å; F235-F247 HydrophobicContact CE1-CE1 4.36Å; F235-F247 HydrophobicContact CE1-CE2 4.26Å; F235-F247 AromaticContact CE1-CG 3.68Å; F235-F247 HydrophobicContact CE1-CG 3.68Å; F235-F247 HydrophobicContact CE1-CZ 4.49Å; F235-V269 HydrophobicContact CE2-CG1 4.5Å; F235-V269 HydrophobicContact CZ-CG1 4.33Å; F235-Y276 HydrophobicContact CB-CD1 3.95Å; F235-Y276 HydrophobicContact CB-CD2 3.79Å; F235-Y276 HydrophobicContact CB-CE1 4.28Å; F235-Y276 HydrophobicContact CB-CE2 4.18Å; F235-Y276 HydrophobicContact CB-CG 3.7Å; F235-Y276 AromaticContact CD2-CD2 3.79Å; F235-Y276 HydrophobicContact CD2-CD2 3.79Å; F235-Y276 AromaticContact CD2-CE2 3.78Å; F235-Y276 HydrophobicContact CD2-CE2 3.78Å; F235-Y276 HydrophobicContact CG-CD2 4.27Å; F235-L278 HydrophobicContact CB-CD1 4.03Å; F235-L278 HydrophobicContact CD1-CD1 3.83Å; F235-L278 HydrophobicContact CD2-CD1 4.34Å; F235-L278 HydrophobicContact CE1-CD1 4.36Å; F235-L278 HydrophobicContact CG-CD1 3.82Å; F235-L309 HydrophobicContact CE1-CD1 4.31Å; F235-L309 HydrophobicContact CE2-CD2 4.41Å; F235-L309 HydrophobicContact CZ-CD1 3.96Å; F235-L309 HydrophobicContact CZ-CD2 4.29Å
236N98.7Very high98.5Very high65 Ų6544.5 Ų44.535%0.34824%0.243SC..Hα-helixtrans-67.6-44.7-179.6-167.623.9000112.1H232 A233 A234 A238 S239 T240 Y276H232-N236 PolarHBondContact O-N 2.66Å; A233-N236 PolarHBondContact O-N 2.68Å; A234-N236 PolarHBondContact O-N 2.87Å; N236-A238 PolarHBondContact O-N 3.44Å; N236-S239 PolarHBondContact O-N 3.34Å; N236-T240 WeakPolarHBondContact O-CG2 3.49Å; N236-T240 PolarHBondContact O-N 3.4Å; N236-T240 PolarHBondContact O-OG1 3.23Å; N236-Y276 HydrophobicContact CB-CD1 4Å; N236-Y276 HydrophobicContact CB-CE1 4.26Å
237F98.7Very high98.5Very high121 Ų12144.3 Ų44.353%0.53124%0.242SC..Hα-helixtrans-65.3-40.6178.5-86-122.7000111.7V202 A233 A234 S239 T240 L241V202-F237 HydrophobicContact CG1-CB 3.97Å; A233-F237 WeakPolarHBondContact O-CB 3.29Å; A233-F237 VanDerWaalsContact O-CD2 3.27Å; A233-F237 WeakPolarHBondContact O-CD2 3.42Å; A233-F237 PolarHBondContact O-N 3.49Å; A234-F237 PolarHBondContact O-N 2.79Å; F237-S239 VanDerWaalsContact C-N 3.32Å; F237-S239 PolarHBondContact O-N 2.82Å; F237-T240 PolarHBondContact O-OG1 2.88Å; F237-L241 HydrophobicContact CB-CD1 4.46Å; F237-L241 HydrophobicContact CD1-CD1 4.1Å; F237-L241 WeakPolarHBondContact O-CB 3.41Å; F237-L241 VanDerWaalsContact O-CG 3.3Å; F237-L241 WeakPolarHBondContact O-CG 3.44Å; F237-L241 PolarHBondContact O-N 2.97Å
238A98.7Very high98.5Very high0 Ų041.6 Ų41.60%022%0.223CC..Hα-helixtrans-59.2-44.1177.700000112V202 A234 N236 R242 C243 V245 F247 L278 P307V202-A238 HydrophobicContact CG1-CB 4.24Å; V202-A238 HydrophobicContact CG2-CB 3.96Å; A234-A238 VanDerWaalsContact O-CB 3.23Å; A234-A238 WeakPolarHBondContact O-CB 3.47Å; A234-A238 PolarHBondContact O-N 3.45Å; N236-A238 PolarHBondContact O-N 3.44Å; A238-R242 CarbonylContact O-C 3.49Å; A238-R242 WeakPolarHBondContact O-CA 3.26Å; A238-R242 PolarHBondContact O-N 3.47Å; A238-C243 PolarHBondContact O-N 2.92Å; A238-V245 HydrophobicContact CB-CG1 3.63Å; A238-F247 HydrophobicContact CB-CE2 3.56Å; A238-F247 HydrophobicContact CB-CZ 3.8Å; A238-L278 HydrophobicContact CB-CD2 4.5Å; A238-P307 HydrophobicContact CB-CB 3.95Å; A238-P307 HydrophobicContact CB-CG 4.3Å
239S97.6Very high98.5Very high30 Ų3037.1 Ų37.121%0.2120%0.202CC..Hα-helixtrans-68.2-56.7-179.9-179.90000112.3F235 N236 F237 L241 R242 Y276F235-S239 PolarHBondContact O-N 3.06Å; N236-S239 PolarHBondContact O-N 3.34Å; F237-S239 VanDerWaalsContact C-N 3.32Å; F237-S239 PolarHBondContact O-N 2.82Å; S239-L241 PolarHBondContact O-N 3.41Å; S239-R242 PolarHBondContact O-N 3.47Å; S239-Y276 WeakPolarHBondContact CB-O 3.2Å; S239-Y276 PolarHBondContact OG-O 2.8Å
240T97.1Very high98.5Very high93 Ų9334.6 Ų34.657%0.57118%0.175SC*.Hα-helixtrans-61-34.9-177.554.50000112.3N236 F237N236-T240 WeakPolarHBondContact O-CG2 3.49Å; N236-T240 PolarHBondContact O-N 3.4Å; N236-T240 PolarHBondContact O-OG1 3.23Å; F237-T240 PolarHBondContact O-OG1 2.88Å
241L98.1Very high98.5Very high57 Ų5731.9 Ų31.930%0.29816%0.161SC..THydrogen-bonded Turntrans-92.91.4177.2-57175.4000113.2Y206 K209 F237 S239 C243Y206-L241 HydrophobicContact CD2-CB 3.8Å; Y206-L241 HydrophobicContact CD2-CD1 4.07Å; Y206-L241 HydrophobicContact CD2-CG 4.4Å; Y206-L241 HydrophobicContact CE2-CB 3.84Å; Y206-L241 HydrophobicContact CE2-CD1 4.16Å; Y206-L241 HydrophobicContact CE2-CD2 3.99Å; Y206-L241 HydrophobicContact CE2-CG 4.23Å; K209-L241 PolarHBondContact NZ-O 3.11Å; F237-L241 HydrophobicContact CB-CD1 4.46Å; F237-L241 HydrophobicContact CD1-CD1 4.1Å; F237-L241 WeakPolarHBondContact O-CB 3.41Å; F237-L241 VanDerWaalsContact O-CG 3.3Å; F237-L241 WeakPolarHBondContact O-CG 3.44Å; F237-L241 PolarHBondContact O-N 2.97Å; S239-L241 PolarHBondContact O-N 3.41Å; L241-C243 VanDerWaalsContact C-N 3.31Å; L241-C243 PolarHBondContact O-N 2.95Å
242R97.6Very high98.5Very high150 Ų15032 Ų3257%0.56616%0.161SC*.THydrogen-bonded Turntrans4850.3179.7-62.7-176.463.6177.1-2.6112.8K209 A238 S239 G305K209-R242 WeakPolarHBondContact CD-O 3.36Å; A238-R242 CarbonylContact O-C 3.49Å; A238-R242 WeakPolarHBondContact O-CA 3.26Å; A238-R242 PolarHBondContact O-N 3.47Å; S239-R242 PolarHBondContact O-N 3.47Å; R242-G305 WeakPolarHBondContact CB-O 3.34Å; R242-G305 PolarHBondContact NE-O 3.15Å
243C98.5Very high98.4Very high0 Ų028.2 Ų28.20%015%0.147CC..  trans-76.4143.1-174.5-68.10000112.2V202 A205 A238 L241 V245V202-C243 HydrophobicContact CG1-CB 4.33Å; A205-C243 HydrophobicContact CB-CB 3.97Å; A238-C243 PolarHBondContact O-N 2.92Å; L241-C243 VanDerWaalsContact C-N 3.31Å; L241-C243 PolarHBondContact O-N 2.95Å; C243-V245 HydrophobicContact CB-CG1 4Å; C243-V245 PolarHBondContact O-N 3.26Å
244P98.6Very high98.3Very high6 Ų627.8 Ų27.84%0.03914%0.139CC..  trans-75.869.6171.532.7-36.3000111.1A205 K209 V216 S217 A302A205-P244 HydrophobicContact CB-CG 4.07Å; A205-P244 WeakPolarHBondContact CB-O 3.5Å; A205-P244 VanDerWaalsContact O-CD 3.28Å; A205-P244 WeakPolarHBondContact O-CD 3.46Å; A205-P244 VanDerWaalsContact O-CG 3.29Å; A205-P244 WeakPolarHBondContact O-CG 3.06Å; K209-P244 HydrophobicContact CB-CG 4.1Å; V216-P244 VanDerWaalsContact CA-O 3.3Å; V216-P244 WeakPolarHBondContact CA-O 3.4Å; V216-P244 WeakPolarHBondContact CB-O 3.13Å; V216-P244 HydrophobicContact CG1-CB 4.29Å; S217-P244 PolarHBondContact N-O 3.23Å; P244-A302 VanDerWaalsContact CA-O 3.26Å; P244-A302 WeakPolarHBondContact CA-O 3.33Å; P244-A302 WeakPolarHBondContact CB-O 3.38Å
245V98.8Very high98.3Very high0 Ų029 Ų290%015%0.149CC..EExtended strand (participates in β ladder)trans-125.7140.5-177.264.50000111.1A201 A205 S217 A238 C243 F247 P307 C308A201-V245 HydrophobicContact CB-CG2 4.43Å; A205-V245 HydrophobicContact CB-CB 3.88Å; S217-V245 CarbonylContact O-C 3.6Å; S217-V245 VanDerWaalsContact O-CA 3.29Å; S217-V245 WeakPolarHBondContact O-CA 3.19Å; S217-V245 WeakPolarHBondContact O-CG2 3.46Å; A238-V245 HydrophobicContact CB-CG1 3.63Å; C243-V245 HydrophobicContact CB-CG1 4Å; C243-V245 PolarHBondContact O-N 3.26Å; V245-F247 HydrophobicContact CG1-CD2 4.45Å; V245-F247 HydrophobicContact CG1-CE2 3.79Å; V245-F247 HydrophobicContact CG1-CZ 3.98Å; V245-F247 HydrophobicContact CG2-CD1 4.49Å; V245-F247 HydrophobicContact CG2-CE1 4.14Å; V245-F247 HydrophobicContact CG2-CE2 4.45Å; V245-F247 HydrophobicContact CG2-CZ 4.14Å; V245-P307 HydrophobicContact CG1-CB 3.79Å; V245-P307 WeakPolarHBondContact O-CA 3.3Å; V245-C308 PolarHBondContact O-N 2.81Å
246I98.9Very high98.2Very high0 Ų033.2 Ų33.20%017%0.171CC..EExtended strand (participates in β ladder)trans-114.4115.4172.6-53171.1000107.7L133 V216 S217 L218 C219 A298 R299 A302 C308 I310L133-I246 HydrophobicContact CD2-CD1 4.44Å; V216-I246 HydrophobicContact CG2-CD1 4.11Å; S217-I246 PolarHBondContact O-N 2.92Å; L218-I246 WeakPolarHBondContact CA-O 3.27Å; L218-I246 HydrophobicContact CD1-CB 4.36Å; L218-I246 HydrophobicContact CD1-CD1 4.48Å; L218-I246 HydrophobicContact CD1-CG2 4.22Å; L218-I246 HydrophobicContact CG-CB 4.29Å; L218-I246 HydrophobicContact CG-CG2 4.46Å; C219-I246 PolarHBondContact N-O 3.47Å; I246-A298 HydrophobicContact CD1-CB 4.07Å; I246-A298 HydrophobicContact CG1-CB 4.23Å; I246-A298 HydrophobicContact CG2-CB 4.12Å; I246-R299 HydrophobicContact CD1-CB 4.08Å; I246-A302 HydrophobicContact CG1-CB 4.06Å; I246-C308 HydrophobicContact CG2-CB 4.39Å; I246-I310 HydrophobicContact CG2-CD1 3.92Å; I246-I310 HydrophobicContact CG2-CG1 4.4Å
247F98.9Very high98.2Very high0 Ų033 Ų330%017%0.174CC..EExtended strand (participates in β ladder)trans-86.6118.7170.5-65.4-66.4000108.8M198 V202 C219 F221 A234 F235 A238 V245 L278 C308 L309 I310M198-F247 HydrophobicContact CE-CD1 4.14Å; M198-F247 HydrophobicContact CE-CE1 4.39Å; V202-F247 HydrophobicContact CG2-CE1 4.12Å; V202-F247 HydrophobicContact CG2-CZ 3.57Å; C219-F247 HydrophobicContact CB-CD1 4.15Å; F221-F247 HydrophobicContact CE1-CB 3.77Å; F221-F247 HydrophobicContact CE1-CD1 4.35Å; F221-F247 HydrophobicContact CZ-CB 4.23Å; A234-F247 HydrophobicContact CB-CE1 4.01Å; A234-F247 HydrophobicContact CB-CZ 4.05Å; F235-F247 HydrophobicContact CD1-CD1 4.28Å; F235-F247 AromaticContact CD1-CD2 3.81Å; F235-F247 HydrophobicContact CD1-CD2 3.81Å; F235-F247 HydrophobicContact CD1-CE1 4.27Å; F235-F247 AromaticContact CD1-CE2 3.77Å; F235-F247 HydrophobicContact CD1-CE2 3.77Å; F235-F247 HydrophobicContact CD1-CG 4.05Å; F235-F247 HydrophobicContact CD1-CZ 4Å; F235-F247 HydrophobicContact CE1-CB 4.02Å; F235-F247 AromaticContact CE1-CD1 3.96Å; F235-F247 HydrophobicContact CE1-CD1 3.96Å; F235-F247 AromaticContact CE1-CD2 3.86Å; F235-F247 HydrophobicContact CE1-CD2 3.86Å; F235-F247 HydrophobicContact CE1-CE1 4.36Å; F235-F247 HydrophobicContact CE1-CE2 4.26Å; F235-F247 AromaticContact CE1-CG 3.68Å; F235-F247 HydrophobicContact CE1-CG 3.68Å; F235-F247 HydrophobicContact CE1-CZ 4.49Å; A238-F247 HydrophobicContact CB-CE2 3.56Å; A238-F247 HydrophobicContact CB-CZ 3.8Å; V245-F247 HydrophobicContact CG1-CD2 4.45Å; V245-F247 HydrophobicContact CG1-CE2 3.79Å; V245-F247 HydrophobicContact CG1-CZ 3.98Å; V245-F247 HydrophobicContact CG2-CD1 4.49Å; V245-F247 HydrophobicContact CG2-CE1 4.14Å; V245-F247 HydrophobicContact CG2-CE2 4.45Å; V245-F247 HydrophobicContact CG2-CZ 4.14Å; F247-L278 HydrophobicContact CD2-CD1 4.13Å; F247-L278 HydrophobicContact CE2-CD1 4.37Å; F247-C308 WeakPolarHBondContact CB-O 3.35Å; F247-C308 WeakPolarHBondContact CD2-O 3.1Å; F247-C308 PolarHBondContact N-O 3.47Å; F247-L309 HydrophobicContact CB-CD1 3.77Å; F247-L309 WeakPolarHBondContact O-CA 3.42Å; F247-I310 PolarHBondContact O-N 3.05Å
248F98.9Very high98.1Very high0 Ų029.7 Ų29.70%016%0.164CC..EExtended strand (participates in β ladder)trans-113.396.3-180-164-73.6000109.6C125 L218 C219 Y220 F221 R250 I291 V295 I310 A312C125-F248 HydrophobicContact CB-CE1 4.05Å; C125-F248 HydrophobicContact CB-CZ 4.3Å; L218-F248 HydrophobicContact CD2-CB 4.14Å; L218-F248 HydrophobicContact CG-CB 4.45Å; C219-F248 PolarHBondContact O-N 2.95Å; Y220-F248 WeakPolarHBondContact CA-O 3.35Å; Y220-F248 HydrophobicContact CD1-CB 3.94Å; Y220-F248 AromaticContact CD1-CD1 3.66Å; Y220-F248 HydrophobicContact CD1-CD1 3.66Å; Y220-F248 HydrophobicContact CD1-CE1 4.45Å; Y220-F248 AromaticContact CD1-CG 3.97Å; Y220-F248 HydrophobicContact CD1-CG 3.97Å; Y220-F248 HydrophobicContact CE1-CB 4.24Å; Y220-F248 AromaticContact CE1-CD1 3.82Å; Y220-F248 HydrophobicContact CE1-CD1 3.82Å; Y220-F248 HydrophobicContact CE1-CE1 4.33Å; Y220-F248 AromaticContact CE1-CG 3.97Å; Y220-F248 HydrophobicContact CE1-CG 3.97Å; F221-F248 PolarHBondContact N-O 2.91Å; F221-F248 VanDerWaalsContact N-O 3.16Å; F248-R250 HydrophobicContact CD1-CG 4.15Å; F248-R250 HydrophobicContact CE1-CG 4.05Å; F248-I291 HydrophobicContact CE2-CD1 4.44Å; F248-I291 HydrophobicContact CE2-CG2 4.03Å; F248-I291 HydrophobicContact CZ-CD1 3.93Å; F248-I291 HydrophobicContact CZ-CG2 3.96Å; F248-V295 HydrophobicContact CD2-CG2 3.85Å; F248-V295 HydrophobicContact CE2-CG2 3.63Å; F248-I310 HydrophobicContact CD2-CB 4.14Å; F248-I310 HydrophobicContact CD2-CD1 4.22Å; F248-I310 HydrophobicContact CD2-CG2 4.1Å; F248-I310 HydrophobicContact CE2-CG2 3.97Å; F248-A312 HydrophobicContact CE1-CB 3.66Å; F248-A312 HydrophobicContact CZ-CB 3.75Å
249C98.8Very high98.1Very high0 Ų030.7 Ų30.70%017%0.171CC..EExtended strand (participates in β ladder)trans-82.9121.4176.6-177.60000110.2F221 V269 I310 E311 A312F221-C249 HydrophobicContact CD2-CB 4.3Å; F221-C249 HydrophobicContact CE1-CB 4.15Å; F221-C249 HydrophobicContact CE2-CB 3.64Å; F221-C249 HydrophobicContact CZ-CB 3.54Å; F221-C249 CarbonylContact O-C 3.49Å; F221-C249 VanDerWaalsContact O-CA 3.32Å; F221-C249 WeakPolarHBondContact O-CA 3.46Å; C249-V269 HydrophobicContact CB-CB 4.32Å; C249-V269 HydrophobicContact CB-CG1 4.11Å; C249-V269 VanDerWaalsContact SG-CG2 3.54Å; C249-I310 PolarHBondContact N-O 3.32Å; C249-E311 HydrophobicContact CB-CG 4.47Å; C249-A312 PolarHBondContact O-N 3.21Å
250R98.6Very high98Very high2 Ų231 Ų311%0.00817%0.171CC..EExtended strand (participates in β ladder)trans-91.397.9167.5-66.8-177.1-66.186.67.5108.7E122 C125 Q142 E145 F221 G222 D223 F248 N252E122-R250 IonicContact OE1-NH1 3.92Å; E122-R250 PolarHBondContact OE1-NH1 3.28Å; E122-R250 WeakPolarHBondContact OE2-CB 3.41Å; E122-R250 VanDerWaalsContact OE2-CD 3.26Å; E122-R250 WeakPolarHBondContact OE2-CD 3.44Å; E122-R250 IonicContact OE2-CZ 3.52Å; E122-R250 IonicContact OE2-NE 3.04Å; E122-R250 IonicContact OE2-NH1 3.59Å; E122-R250 PolarHBondContact OE2-NH1 3.39Å; C125-R250 HydrophobicContact CB-CG 4.4Å; Q142-R250 VanDerWaalsContact OE1-NH2 3.1Å; E145-R250 IonicContact OE1-CZ 2.73Å; E145-R250 IonicContact OE1-NE 3.94Å; E145-R250 PolarHBondContact OE1-NE 3.17Å; E145-R250 IonicContact OE1-NH2 3.99Å; E145-R250 PolarHBondContact OE1-NH2 2.93Å; E145-R250 IonicContact OE2-NH2 3.68Å; F221-R250 PolarHBondContact O-N 3.06Å; G222-R250 WeakPolarHBondContact CA-O 3.35Å; D223-R250 PolarHBondContact N-O 3.25Å; F248-R250 HydrophobicContact CD1-CG 4.15Å; F248-R250 HydrophobicContact CE1-CG 4.05Å; R250-N252 PolarHBondContact O-N 2.99Å
251N98.5Very high97.9Very high5 Ų531.3 Ų31.33%0.02718%0.177CC..EExtended strand (participates in β ladder)trans-88.399.7175-171.2-25.1000108.4D223 A253 Y264 E311 A312 M313 T314D223-N251 HydrophobicContact CB-CB 4.26Å; N251-A253 PolarHBondContact OD1-N 3.03Å; N251-Y264 PolarHBondContact ND2-OH 3.36Å; N251-E311 HydrophobicContact CB-CG 3.98Å; N251-E311 PolarHBondContact ND2-OE1 2.8Å; N251-A312 PolarHBondContact N-O 2.91Å; N251-M313 HydrophobicContact CB-CE 4.13Å; N251-M313 HydrophobicContact CB-SD 3.98Å; N251-T314 PolarHBondContact O-N 3.29Å
252N97.5Very high97.9Very high6 Ų635.3 Ų35.33%0.03219%0.194CC..  trans-109.919.7-173.871.711.9000112.9E122 D223 R250 Y254 T314 R316E122-N252 PolarHBondContact OE1-ND2 3.27Å; D223-N252 PolarHBondContact OD1-N 2.98Å; D223-N252 VanDerWaalsContact OD1-N 3.16Å; D223-N252 PolarHBondContact OD1-OD1 3.43Å; R250-N252 PolarHBondContact O-N 2.99Å; N252-Y254 PolarHBondContact O-N 3.32Å; N252-Y254 PolarHBondContact OD1-N 3.04Å; N252-Y254 PolarHBondContact OD1-O 3.4Å; N252-Y254 VanDerWaalsContact OD1-O 3.06Å; N252-T314 WeakPolarHBondContact CA-O 3.48Å; N252-T314 HydrophobicContact CB-CG2 3.75Å; N252-R316 HydrophobicContact CB-CB 4.07Å; N252-R316 PolarHBondContact O-N 3.22Å
253A96.6Very high97.9Very high22 Ų2230.1 Ų30.118%0.18218%0.177CC..SBendtrans70.7-11.2179.900000117.1N251 V260 Y315N251-A253 PolarHBondContact OD1-N 3.03Å; A253-V260 PolarHBondContact O-N 3.11Å; A253-Y315 HydrophobicContact CB-CD2 4.41Å
254Y98.1Very high97.8Very high25 Ų2532.3 Ų32.310%0.09819%0.185CC..EExtended strand (participates in β ladder)trans-145.1127.9-172.6-72.4-86.5000115.3N252 T258 Y315 R316 Y329 R330 E334N252-Y254 PolarHBondContact O-N 3.32Å; N252-Y254 PolarHBondContact OD1-N 3.04Å; N252-Y254 PolarHBondContact OD1-O 3.4Å; N252-Y254 VanDerWaalsContact OD1-O 3.06Å; Y254-T258 WeakPolarHBondContact CA-O 3.29Å; Y254-Y315 HydrophobicContact CD2-CE2 4.43Å; Y254-Y315 HydrophobicContact CE2-CE2 4.1Å; Y254-R316 PolarHBondContact O-NH1 3.37Å; Y254-Y329 HydrophobicContact CD1-CD2 4.27Å; Y254-Y329 HydrophobicContact CD1-CE2 4.19Å; Y254-Y329 HydrophobicContact CE1-CD2 4.21Å; Y254-Y329 HydrophobicContact CE1-CE2 4.49Å; Y254-R330 HydrophobicContact CD1-CG 4.38Å; Y254-R330 HydrophobicContact CE1-CG 3.81Å; Y254-R330 VanDerWaalsContact CE2-CD 3.47Å; Y254-R330 HydrophobicContact CE2-CG 4.04Å; Y254-E334 PolarHBondContact OH-OE1 3.11Å; Y254-E334 PolarHBondContact OH-OE2 3.11Å
255A98Very high97.5Very high26 Ų2635.8 Ų35.822%0.21522%0.223CC..EExtended strand (participates in β ladder)trans-100.799.9164.900000110.3S257 T258A255-S257 PolarHBondContact O-N 3.18Å; A255-T258 PolarHBondContact N-O 3.44Å; A255-T258 WeakPolarHBondContact O-CB 3.47Å; A255-T258 PolarHBondContact O-N 3.05Å
256I97.8Very high97.3Very high90 Ų9037.9 Ų37.946%0.46224%0.244SC..THydrogen-bonded Turntrans55.9-102.1-167.1-51.5174.7000109.3R316 Y329I256-R316 PolarHBondContact O-NH1 3.46Å; I256-R316 PolarHBondContact O-NH2 3.43Å; I256-Y329 VanDerWaalsContact O-CE2 3.26Å; I256-Y329 WeakPolarHBondContact O-CE2 3.21Å; I256-Y329 VanDerWaalsContact O-CZ 3.22Å; I256-Y329 PolarHBondContact O-OH 2.85Å
257S97.4Very high97.1Very high60 Ų6040 Ų4042%0.4226%0.255SS..THydrogen-bonded Turntrans-103.5-14.317760.60000114.2A255A255-S257 PolarHBondContact O-N 3.18Å
258T97.9Very high97Very high51 Ų5140.2 Ų40.231%0.31326%0.258SS..EExtended strand (participates in β ladder)trans-77.8123.3-176.8-56.10000110.2Y254 A255 E262Y254-T258 WeakPolarHBondContact CA-O 3.29Å; A255-T258 PolarHBondContact N-O 3.44Å; A255-T258 WeakPolarHBondContact O-CB 3.47Å; A255-T258 PolarHBondContact O-N 3.05Å; T258-E262 HydrophobicContact CG2-CB 3.73Å
259S97Very high96.9Very high22 Ų2240.2 Ų40.215%0.15426%0.258CS..EExtended strand (participates in β ladder)trans-76158.3176.763.90000111.7S261 E262 Q263S259-S261 PolarHBondContact O-N 3.24Å; S259-S261 PolarHBondContact OG-OG 3.43Å; S259-E262 PolarHBondContact N-OE2 3.45Å; S259-E262 PolarHBondContact O-N 3Å; S259-E262 PolarHBondContact OG-OE2 3.41Å; S259-E262 VanDerWaalsContact OG-OE2 3.06Å; S259-Q263 PolarHBondContact O-N 2.89Å
260V96.4Very high96.9Very high35 Ų3540.2 Ų40.221%0.21226%0.258CS..Hα-helixtrans-58.4-29.7175.5-76.50000114D223 A253 E262 Q263 Y264D223-V260 HydrophobicContact CB-CG1 4.37Å; A253-V260 PolarHBondContact O-N 3.11Å; V260-E262 PolarHBondContact O-N 3.49Å; V260-Q263 WeakPolarHBondContact O-CB 3.47Å; V260-Q263 PolarHBondContact O-N 2.95Å; V260-Y264 HydrophobicContact CB-CE1 4.14Å; V260-Y264 HydrophobicContact CB-CE2 4.48Å; V260-Y264 WeakPolarHBondContact CB-OH 3.11Å; V260-Y264 HydrophobicContact CG1-CE1 4Å; V260-Y264 WeakPolarHBondContact CG1-OH 3.32Å; V260-Y264 PolarHBondContact O-N 3.23Å
261S95Very high96.8Very high100 Ų10041.8 Ų41.870%0.69927%0.274SS*.Hα-helixtrans-65.5-21.4174.741.10000113.8S259S259-S261 PolarHBondContact O-N 3.24Å; S259-S261 PolarHBondContact OG-OG 3.43Å
262E97.4Very high96.7Very high141 Ų14144.4 Ų44.466%0.65928%0.284SS*.Hα-helixtrans-99.8-5.6173.9-63.3167.4135.700111.8T258 S259 V260T258-E262 HydrophobicContact CG2-CB 3.73Å; S259-E262 PolarHBondContact N-OE2 3.45Å; S259-E262 PolarHBondContact O-N 3Å; S259-E262 PolarHBondContact OG-OE2 3.41Å; S259-E262 VanDerWaalsContact OG-OE2 3.06Å; V260-E262 PolarHBondContact O-N 3.49Å
263Q97.8Very high96.7Very high42 Ų4244.1 Ų44.120%0.19628%0.282CS..Hα-helixtrans-92.7-39.6-176.7-166.662.6-95.500112.1G224 S227 S259 V260G224-Q263 VanDerWaalsContact CA-NE2 3.28Å; S227-Q263 PolarHBondContact OG-OE1 3.1Å; S259-Q263 PolarHBondContact O-N 2.89Å; V260-Q263 WeakPolarHBondContact O-CB 3.47Å; V260-Q263 PolarHBondContact O-N 2.95Å
264Y96.1Very high96.7Very high45 Ų4546.6 Ų46.618%0.17630%0.296CS..  trans-156.1154.5-179.952.3-105.3000112D223 N251 V260 G266 G268D223-Y264 HydrophobicContact CB-CE1 4.44Å; N251-Y264 PolarHBondContact ND2-OH 3.36Å; V260-Y264 HydrophobicContact CB-CE1 4.14Å; V260-Y264 HydrophobicContact CB-CE2 4.48Å; V260-Y264 WeakPolarHBondContact CB-OH 3.11Å; V260-Y264 HydrophobicContact CG1-CE1 4Å; V260-Y264 WeakPolarHBondContact CG1-OH 3.32Å; V260-Y264 PolarHBondContact O-N 3.23Å; Y264-G266 WeakPolarHBondContact CD2-O 3.4Å; Y264-G268 VanDerWaalsContact CE2-CA 3.47Å
265G93.5Very high96.5Very high80 Ų8049.8 Ų49.883%0.82533%0.328SS*.SBendtrans-101.67.1176.100000115.2
266G93.4Very high96.5Very high43 Ų4351.4 Ų51.444%0.44333%0.329SS..SBendtrans-106.1-175.6-177.900000113.8Y264 G268Y264-G266 WeakPolarHBondContact CD2-O 3.4Å; G266-G268 PolarHBondContact O-N 3.24Å
267D95.2Very high96.3Very high44 Ų4448.7 Ų48.724%0.23532%0.323CS..SBendtrans-73.568.4175.5-179.327000112T60 I61 G271 R282T60-D267 VanDerWaalsContact CA-OD2 3.3Å; T60-D267 WeakPolarHBondContact CA-OD2 3.42Å; T60-D267 WeakPolarHBondContact CB-OD1 3.47Å; T60-D267 HydrophobicContact CG2-CB 4.3Å; I61-D267 PolarHBondContact N-OD2 3.2Å; D267-G271 WeakPolarHBondContact O-CA 3.28Å; D267-G271 PolarHBondContact O-N 3.35Å; D267-R282 VanDerWaalsContact C-NH2 3.32Å; D267-R282 PolarHBondContact O-NH2 3.23Å; D267-R282 IonicContact OD1-CZ 3.99Å; D267-R282 IonicContact OD1-NH1 2.92Å; D267-R282 PolarHBondContact OD1-NH1 2.77Å; D267-R282 IonicContact OD1-NH2 3.69Å; D267-R282 PolarHBondContact OD1-NH2 2.88Å; D267-R282 IonicContact OD2-CZ 3.96Å; D267-R282 IonicContact OD2-NH1 3.57Å; D267-R282 IonicContact OD2-NH2 3.35Å
268G96.5Very high96.4Very high6 Ų646.2 Ų46.26%0.06231%0.305CS..THydrogen-bonded Turntrans62.7-158.4178.700000113.8Y264 G266Y264-G268 VanDerWaalsContact CE2-CA 3.47Å; G266-G268 PolarHBondContact O-N 3.24Å
269V98.2Very high96.4Very high0 Ų045.2 Ų45.20%030%0.302CS..THydrogen-bonded Turntrans-81.5-35172-175.70000110.4F221 S226 F235 C249 G271 R272 L309 E311F221-V269 HydrophobicContact CE2-CG1 4.01Å; F221-V269 HydrophobicContact CZ-CG1 4.34Å; S226-V269 WeakPolarHBondContact OG-CG2 3.4Å; F235-V269 HydrophobicContact CE2-CG1 4.5Å; F235-V269 HydrophobicContact CZ-CG1 4.33Å; C249-V269 HydrophobicContact CB-CB 4.32Å; C249-V269 HydrophobicContact CB-CG1 4.11Å; C249-V269 VanDerWaalsContact SG-CG2 3.54Å; V269-G271 VanDerWaalsContact C-N 3.29Å; V269-G271 PolarHBondContact O-N 3.38Å; V269-R272 VanDerWaalsContact O-CB 3.32Å; V269-R272 WeakPolarHBondContact O-CB 3.49Å; V269-R272 PolarHBondContact O-N 3.04Å; V269-L309 HydrophobicContact CG1-CD1 4.31Å; V269-L309 HydrophobicContact CG1-CD2 4.34Å; V269-L309 WeakPolarHBondContact O-CD2 3.38Å; V269-E311 HydrophobicContact CB-CG 4.44Å; V269-E311 PolarHBondContact N-OE1 3.41Å
270A98.3Very high96.5Very high0 Ų045.9 Ų45.90%031%0.306CS..G310 helixtrans-57.9-40177.400000112I61 R272 G273 P274 T280 R282 E311I61-A270 HydrophobicContact CD1-CB 3.69Å; I61-A270 WeakPolarHBondContact CD1-O 3.36Å; A270-R272 PolarHBondContact O-N 3.5Å; A270-G273 PolarHBondContact O-N 2.86Å; A270-P274 WeakPolarHBondContact O-CD 3.39Å; A270-T280 HydrophobicContact CB-CG2 3.86Å; A270-T280 WeakPolarHBondContact O-CG2 3.15Å; A270-R282 HydrophobicContact CB-CB 4.27Å; A270-E311 HydrophobicContact CB-CB 3.83Å; A270-E311 WeakPolarHBondContact CB-OE2 3.48Å; A270-E311 PolarHBondContact N-OE2 3.18Å
271G96.3Very high96.6Very high34 Ų3447 Ų4735%0.35131%0.31SS..G310 helixtrans-58-20178.100000114.2D267 V269D267-G271 WeakPolarHBondContact O-CA 3.28Å; D267-G271 PolarHBondContact O-N 3.35Å; V269-G271 VanDerWaalsContact C-N 3.29Å; V269-G271 PolarHBondContact O-N 3.38Å
272R97.2Very high96.8Very high60 Ų6043 Ų4323%0.22628%0.279CS..G310 helixtrans-80.3-32.5177.6-50-179.7-169.9-175.33.4112.5S226 V269 A270 A275 Y276S226-R272 PolarHBondContact O-NH1 3.19Å; S226-R272 PolarHBondContact OG-NH1 3.2Å; S226-R272 PolarHBondContact OG-NH2 3.14Å; V269-R272 VanDerWaalsContact O-CB 3.32Å; V269-R272 WeakPolarHBondContact O-CB 3.49Å; V269-R272 PolarHBondContact O-N 3.04Å; A270-R272 PolarHBondContact O-N 3.5Å; R272-A275 WeakPolarHBondContact O-CB 3.34Å; R272-A275 PolarHBondContact O-N 2.86Å; R272-Y276 HydrophobicContact CB-CE2 4.29Å; R272-Y276 WeakPolarHBondContact O-CD2 3.33Å
273G97.8Very high96.8Very high0 Ų036.2 Ų36.20%025%0.248CC..Hα-helixtrans-58.1-50.6-170.400000115A270 A275 Y276 G277 L278 T280A270-G273 PolarHBondContact O-N 2.86Å; G273-A275 PolarHBondContact O-N 3.07Å; G273-Y276 PolarHBondContact O-N 3.27Å; G273-Y276 VanDerWaalsContact O-N 3.08Å; G273-G277 PolarHBondContact O-N 3.37Å; G273-L278 PolarHBondContact O-N 3.31Å; G273-T280 WeakPolarHBondContact CA-OG1 3.47Å
274P95.4Very high96.8Very high74 Ų7435.1 Ų35.148%0.48124%0.243SC..Hα-helixtrans-58-34.3178.6-2836.5000113.7A270 Y276 G277A270-P274 WeakPolarHBondContact O-CD 3.39Å; P274-Y276 VanDerWaalsContact C-N 3.28Å; P274-Y276 PolarHBondContact O-N 2.85Å; P274-G277 PolarHBondContact O-N 3.07Å
275A94Very high96.9Very high92 Ų9233 Ų3376%0.7624%0.235SC*.Hα-helixtrans-64.7-31.2178.600000112.7R272 G273R272-A275 WeakPolarHBondContact O-CB 3.34Å; R272-A275 PolarHBondContact O-N 2.86Å; G273-A275 PolarHBondContact O-N 3.07Å
276Y97.2Very high97Very high60 Ų6029.5 Ų29.524%0.23520%0.197CC..Hα-helixtrans-84.9-10.3171.3-63.8-80.9000113.1H232 F235 N236 S239 R272 G273 P274H232-Y276 AromaticContact CE1-CE1 3.77Å; H232-Y276 AromaticContact ND1-CE1 3.51Å; H232-Y276 AromaticContact ND1-CZ 3.51Å; H232-Y276 PolarHBondContact ND1-OH 3.27Å; F235-Y276 HydrophobicContact CB-CD1 3.95Å; F235-Y276 HydrophobicContact CB-CD2 3.79Å; F235-Y276 HydrophobicContact CB-CE1 4.28Å; F235-Y276 HydrophobicContact CB-CE2 4.18Å; F235-Y276 HydrophobicContact CB-CG 3.7Å; F235-Y276 AromaticContact CD2-CD2 3.79Å; F235-Y276 HydrophobicContact CD2-CD2 3.79Å; F235-Y276 AromaticContact CD2-CE2 3.78Å; F235-Y276 HydrophobicContact CD2-CE2 3.78Å; F235-Y276 HydrophobicContact CG-CD2 4.27Å; N236-Y276 HydrophobicContact CB-CD1 4Å; N236-Y276 HydrophobicContact CB-CE1 4.26Å; S239-Y276 WeakPolarHBondContact CB-O 3.2Å; S239-Y276 PolarHBondContact OG-O 2.8Å; R272-Y276 HydrophobicContact CB-CE2 4.29Å; R272-Y276 WeakPolarHBondContact O-CD2 3.33Å; G273-Y276 PolarHBondContact O-N 3.27Å; G273-Y276 VanDerWaalsContact O-N 3.08Å; P274-Y276 VanDerWaalsContact C-N 3.28Å; P274-Y276 PolarHBondContact O-N 2.85Å
277G95.3Very high97.2Very high33 Ų3327.4 Ų27.434%0.3418%0.176SC..THydrogen-bonded Turntrans83.625.6-173.800000114.4G273 P274G273-G277 PolarHBondContact O-N 3.37Å; P274-G277 PolarHBondContact O-N 3.07Å
278L98.3Very high97.2Very high8 Ų825.4 Ų25.44%0.04217%0.165CC..  trans-84.8141.2174.6-52.2-178.7000111.1F235 A238 F247 G273 T280 P307 L309F235-L278 HydrophobicContact CB-CD1 4.03Å; F235-L278 HydrophobicContact CD1-CD1 3.83Å; F235-L278 HydrophobicContact CD2-CD1 4.34Å; F235-L278 HydrophobicContact CE1-CD1 4.36Å; F235-L278 HydrophobicContact CG-CD1 3.82Å; A238-L278 HydrophobicContact CB-CD2 4.5Å; F247-L278 HydrophobicContact CD2-CD1 4.13Å; F247-L278 HydrophobicContact CE2-CD1 4.37Å; G273-L278 PolarHBondContact O-N 3.31Å; L278-T280 PolarHBondContact O-N 3.36Å; L278-T280 PolarHBondContact O-OG1 3.07Å; L278-P307 HydrophobicContact CD2-CB 3.87Å; L278-P307 HydrophobicContact CD2-CG 3.54Å; L278-L309 HydrophobicContact CB-CB 4.35Å; L278-L309 HydrophobicContact CD1-CB 4.12Å
279A98.3Very high97.2Very high30 Ų3025.6 Ų25.625%0.24816%0.164CC..EExtended strand (participates in β ladder)trans-69.6111.8169.100000109L301 P307 C308 L309A279-L301 HydrophobicContact CB-CD1 4.25Å; A279-P307 PolarHBondContact N-O 3.47Å; A279-C308 CarbonylContact O-C 3.57Å; A279-C308 WeakPolarHBondContact O-CA 3.31Å; A279-L309 PolarHBondContact O-N 3.05Å
280T98.8Very high97Very high37 Ų3725.6 Ų25.623%0.22716%0.164CC..EExtended strand (participates in β ladder)trans-121138.3-162.6-55.60000112.7I61 A270 G273 L278 L309I61-T280 HydrophobicContact CD1-CG2 4.27Å; A270-T280 HydrophobicContact CB-CG2 3.86Å; A270-T280 WeakPolarHBondContact O-CG2 3.15Å; G273-T280 WeakPolarHBondContact CA-OG1 3.47Å; L278-T280 PolarHBondContact O-N 3.36Å; L278-T280 PolarHBondContact O-OG1 3.07Å; T280-L309 CarbonylContact C-O 3.59Å; T280-L309 VanDerWaalsContact CA-O 3.29Å; T280-L309 WeakPolarHBondContact CA-O 3.48Å; T280-L309 HydrophobicContact CG2-CB 4.17Å; T280-L309 HydrophobicContact CG2-CD2 4.06Å; T280-L309 HydrophobicContact CG2-CG 4.19Å
281I98.6Very high97Very high59 Ų5925.6 Ų25.630%0.30316%0.164SC..EExtended strand (participates in β ladder)trans-142.6144.9173.4-170.7163000111F64 L309 I310 E311F64-I281 HydrophobicContact CB-CD1 4.04Å; F64-I281 HydrophobicContact CB-CG1 4.36Å; F64-I281 HydrophobicContact CG-CD1 4.3Å; I281-L309 PolarHBondContact N-O 2.65Å; I281-I310 HydrophobicContact CG2-CB 4.35Å; I281-I310 HydrophobicContact CG2-CG1 3.86Å; I281-I310 HydrophobicContact CG2-CG2 4.33Å; I281-I310 WeakPolarHBondContact O-CA 3.35Å; I281-E311 PolarHBondContact O-N 3.44Å
282R98.7Very high97Very high14 Ų1425.9 Ų25.95%0.05316%0.155CC..EExtended strand (participates in β ladder)trans-104.2137.3166.1-176179.2-70.4153.1-8.1109.4I61 I63 F64 D267 A270 E311 M313I61-R282 HydrophobicContact CB-CB 4.48Å; I61-R282 HydrophobicContact CG2-CB 3.77Å; I61-R282 PolarHBondContact O-NH1 2.96Å; I63-R282 HydrophobicContact CG1-CG 3.99Å; F64-R282 WeakPolarHBondContact CB-O 3.36Å; F64-R282 PolarHBondContact N-O 3.32Å; D267-R282 VanDerWaalsContact C-NH2 3.32Å; D267-R282 PolarHBondContact O-NH2 3.23Å; D267-R282 IonicContact OD1-CZ 3.99Å; D267-R282 IonicContact OD1-NH1 2.92Å; D267-R282 PolarHBondContact OD1-NH1 2.77Å; D267-R282 IonicContact OD1-NH2 3.69Å; D267-R282 PolarHBondContact OD1-NH2 2.88Å; D267-R282 IonicContact OD2-CZ 3.96Å; D267-R282 IonicContact OD2-NH1 3.57Å; D267-R282 IonicContact OD2-NH2 3.35Å; A270-R282 HydrophobicContact CB-CB 4.27Å; R282-E311 CarbonylContact C-O 3.51Å; R282-E311 WeakPolarHBondContact CA-O 3.41Å; R282-E311 HydrophobicContact CG-CB 4.46Å; R282-E311 IonicContact CZ-OE2 2.86Å; R282-E311 IonicContact NE-OE2 3.84Å; R282-E311 PolarHBondContact NE-OE2 2.85Å; R282-E311 IonicContact NH2-OE2 3.21Å; R282-E311 PolarHBondContact NH2-OE2 3.28Å; R282-M313 HydrophobicContact CG-CG 3.55Å; R282-M313 HydrophobicContact CG-SD 3.81Å
283V98.2Very high96.9Very high0 Ų024 Ų240%015%0.151CC..EExtended strand (participates in β ladder)trans-136.4147.2-172.5630000110.8F64 G285 A290 I291 I310 E311 A312 M313F64-V283 HydrophobicContact CB-CG2 4.45Å; F64-V283 HydrophobicContact CD1-CG2 4.03Å; F64-V283 WeakPolarHBondContact O-CG2 3.4Å; V283-G285 PolarHBondContact O-N 3.37Å; V283-A290 HydrophobicContact CG2-CB 3.54Å; V283-I291 HydrophobicContact CB-CD1 4.29Å; V283-I291 HydrophobicContact CG1-CD1 3.4Å; V283-I291 HydrophobicContact CG2-CD1 3.88Å; V283-I310 HydrophobicContact CG1-CG2 3.57Å; V283-E311 PolarHBondContact N-O 3.35Å; V283-A312 HydrophobicContact CG1-CB 4Å; V283-A312 WeakPolarHBondContact O-CA 3.3Å; V283-M313 PolarHBondContact O-N 3.47Å
284D97.6Very high96.8Very high19 Ų1924.4 Ų24.410%0.10215%0.154CC..EExtended strand (participates in β ladder)trans-63.2117.5169.7177.1-14.7000108.1I63 F64 R65 N286 D287 R347I63-D284 HydrophobicContact CG2-CB 3.9Å; F64-D284 PolarHBondContact O-N 3Å; R65-D284 HydrophobicContact CB-CB 4.17Å; R65-D284 WeakPolarHBondContact CD-OD2 3.21Å; R65-D284 HydrophobicContact CG-CB 4.16Å; D284-N286 VanDerWaalsContact C-N 3.29Å; D284-N286 PolarHBondContact O-N 2.98Å; D284-N286 WeakPolarHBondContact OD1-CA 3.12Å; D284-N286 WeakPolarHBondContact OD1-CB 3.1Å; D284-N286 PolarHBondContact OD1-N 3.28Å; D284-D287 HydrophobicContact CB-CB 3.78Å; D284-D287 WeakPolarHBondContact O-CA 3.44Å; D284-D287 PolarHBondContact O-N 2.95Å; D284-D287 PolarHBondContact OD1-N 3.07Å; D284-D287 VanDerWaalsContact OD1-N 3.09Å; D284-R347 IonicContact OD1-NH1 3.07Å; D284-R347 IonicContact OD2-CZ 2.91Å; D284-R347 IonicContact OD2-NH1 3.65Å; D284-R347 PolarHBondContact OD2-NH1 3.42Å
285G97.8Very high96.9Very high0 Ų020.9 Ų20.90%013%0.131CC..SBendtrans-75.9-15.2-177.600000114.4A124 C125 V283 M313A124-G285 WeakPolarHBondContact CB-O 3.39Å; C125-G285 VanDerWaalsContact SG-CA 3.52Å; C125-G285 PolarHBondContact SG-O 3.02Å; V283-G285 PolarHBondContact O-N 3.37Å; G285-M313 VanDerWaalsContact CA-O 3.27Å; G285-M313 WeakPolarHBondContact CA-O 3.48Å; G285-M313 PolarHBondContact N-O 2.78Å
286N97.2Very high97Very high6 Ų619.4 Ų19.43%0.03211%0.108CC..SBendtrans-91.5-19.1174.6-56-39000111.4G121 D284 I288 T314 N342 P344 R347G121-N286 PolarHBondContact O-OD1 3.02Å; D284-N286 VanDerWaalsContact C-N 3.29Å; D284-N286 PolarHBondContact O-N 2.98Å; D284-N286 WeakPolarHBondContact OD1-CA 3.12Å; D284-N286 WeakPolarHBondContact OD1-CB 3.1Å; D284-N286 PolarHBondContact OD1-N 3.28Å; N286-I288 PolarHBondContact O-N 3.44Å; N286-I288 VanDerWaalsContact O-N 3.11Å; N286-T314 PolarHBondContact OD1-OG1 3.06Å; N286-N342 WeakPolarHBondContact CB-O 3.5Å; N286-N342 PolarHBondContact ND2-O 3.19Å; N286-N342 VanDerWaalsContact ND2-O 3.11Å; N286-P344 HydrophobicContact CB-CB 4.21Å; N286-R347 PolarHBondContact O-NE 2.88Å
287D96Very high97Very high0 Ų021.7 Ų21.70%012%0.121CC..  trans-21.139.4142.4-131.4-4.7000127.6R65 V66 M67 D284 F289 A290 I291 R347R65-D287 HydrophobicContact CG-CB 4.27Å; R65-D287 VanDerWaalsContact CG-OD2 3.28Å; R65-D287 WeakPolarHBondContact CG-OD2 3.39Å; V66-D287 WeakPolarHBondContact CA-OD2 3.46Å; V66-D287 PolarHBondContact N-OD2 3.26Å; M67-D287 PolarHBondContact N-OD2 3.07Å; D284-D287 HydrophobicContact CB-CB 3.78Å; D284-D287 WeakPolarHBondContact O-CA 3.44Å; D284-D287 PolarHBondContact O-N 2.95Å; D284-D287 PolarHBondContact OD1-N 3.07Å; D284-D287 VanDerWaalsContact OD1-N 3.09Å; D287-F289 PolarHBondContact O-N 2.98Å; D287-F289 PolarHBondContact OD1-N 3.4Å; D287-A290 HydrophobicContact CB-CB 3.51Å; D287-A290 CarbonylContact O-C 3.53Å; D287-A290 WeakPolarHBondContact O-CA 3.42Å; D287-A290 PolarHBondContact O-N 2.95Å; D287-A290 PolarHBondContact OD1-N 3.33Å; D287-I291 WeakPolarHBondContact O-CG1 3.4Å; D287-I291 PolarHBondContact O-N 3.14Å; D287-R347 VanDerWaalsContact CB-CZ 3.47Å; D287-R347 VanDerWaalsContact N-NH1 3.19Å; D287-R347 IonicContact OD1-NH2 2.76Å; D287-R347 PolarHBondContact OD1-NH2 3.42Å; D287-R347 IonicContact OD2-NH2 3.45Å; D287-R347 PolarHBondContact OD2-NH2 2.94Å; D287-R347 VanDerWaalsContact OD2-NH2 3.07Å
288I96.3Very high97.1Very high1 Ų120.3 Ų20.31%0.00511%0.106CC..Hα-helixtrans-53.7-34.9-170.4-159164.1000115.5M90 M94 A124 I127 N286 Y292 L348M90-I288 HydrophobicContact CB-CD1 3.69Å; M90-I288 HydrophobicContact CG-CD1 4.02Å; M90-I288 HydrophobicContact SD-CD1 3.89Å; M90-I288 HydrophobicContact SD-CG1 3.99Å; M94-I288 HydrophobicContact SD-CD1 3.69Å; A124-I288 HydrophobicContact CB-CB 3.78Å; A124-I288 HydrophobicContact CB-CD1 4.44Å; A124-I288 HydrophobicContact CB-CG1 4.16Å; I127-I288 HydrophobicContact CB-CD1 4.43Å; I127-I288 HydrophobicContact CG2-CD1 4.17Å; N286-I288 PolarHBondContact O-N 3.44Å; N286-I288 VanDerWaalsContact O-N 3.11Å; I288-Y292 WeakPolarHBondContact O-CB 3.5Å; I288-Y292 PolarHBondContact O-N 2.98Å; I288-L348 HydrophobicContact CD1-CD2 4.21Å; I288-L348 HydrophobicContact CG2-CD1 4.07Å; I288-L348 HydrophobicContact CG2-CD2 4.16Å; I288-L348 HydrophobicContact CG2-CG 4.49Å
289F95.3Very high97.1Very high10 Ų1021.4 Ų21.44%0.04411%0.11CC..Hα-helixtrans-76.8-35.2177.1-62.3-45000112V66 M67 L73 I82 A87 D287 S293 L348 F351V66-F289 HydrophobicContact CB-CB 4.15Å; V66-F289 HydrophobicContact CG1-CB 3.86Å; M67-F289 HydrophobicContact CB-CD2 4.44Å; M67-F289 HydrophobicContact CE-CD2 4.11Å; M67-F289 HydrophobicContact CE-CE2 4.19Å; M67-F289 HydrophobicContact SD-CD2 4.14Å; M67-F289 HydrophobicContact SD-CE2 4.01Å; L73-F289 HydrophobicContact CD2-CD2 4.16Å; L73-F289 HydrophobicContact CD2-CE2 4.45Å; I82-F289 HydrophobicContact CB-CE1 4.48Å; I82-F289 HydrophobicContact CD1-CD1 3.99Å; I82-F289 HydrophobicContact CD1-CD2 3.56Å; I82-F289 HydrophobicContact CD1-CE1 4.06Å; I82-F289 HydrophobicContact CD1-CE2 3.62Å; I82-F289 HydrophobicContact CD1-CG 3.77Å; I82-F289 HydrophobicContact CD1-CZ 3.89Å; I82-F289 HydrophobicContact CG1-CD1 4.05Å; I82-F289 HydrophobicContact CG1-CD2 4.49Å; I82-F289 HydrophobicContact CG1-CE1 4.11Å; I82-F289 HydrophobicContact CG1-CG 4.27Å; I82-F289 HydrophobicContact CG1-CZ 4.36Å; I82-F289 HydrophobicContact CG2-CD1 4.23Å; I82-F289 HydrophobicContact CG2-CE1 3.49Å; I82-F289 VanDerWaalsContact CG2-CE1 3.49Å; I82-F289 HydrophobicContact CG2-CE2 4.46Å; I82-F289 HydrophobicContact CG2-CZ 3.63Å; A87-F289 HydrophobicContact CB-CE1 4.11Å; A87-F289 HydrophobicContact CB-CZ 4.07Å; D287-F289 PolarHBondContact O-N 2.98Å; D287-F289 PolarHBondContact OD1-N 3.4Å; F289-S293 WeakPolarHBondContact O-CB 3.27Å; F289-S293 PolarHBondContact O-N 2.7Å; F289-S293 PolarHBondContact O-OG 3.49Å; F289-L348 HydrophobicContact CE1-CD1 4.39Å; F289-L348 HydrophobicContact CE2-CD1 4.2Å; F289-L348 HydrophobicContact CZ-CD1 3.71Å; F289-F351 AromaticContact CE2-CD1 3.74Å; F289-F351 HydrophobicContact CE2-CD1 3.74Å; F289-F351 HydrophobicContact CE2-CD2 4.15Å; F289-F351 AromaticContact CE2-CE1 3.76Å; F289-F351 HydrophobicContact CE2-CE1 3.76Å; F289-F351 HydrophobicContact CE2-CE2 4.16Å; F289-F351 AromaticContact CE2-CG 3.94Å; F289-F351 HydrophobicContact CE2-CG 3.94Å; F289-F351 AromaticContact CE2-CZ 3.97Å; F289-F351 HydrophobicContact CE2-CZ 3.97Å; F289-F351 AromaticContact CZ-CD1 3.71Å; F289-F351 HydrophobicContact CZ-CD1 3.71Å; F289-F351 AromaticContact CZ-CE1 3.51Å; F289-F351 HydrophobicContact CZ-CE1 3.51Å; F289-F351 HydrophobicContact CZ-CG 4.38Å; F289-F351 HydrophobicContact CZ-CZ 4.04Å
290A95.6Very high97.1Very high0 Ų024.7 Ų24.70%012%0.119CC..Hα-helixtrans-66-43.3172.400000111.6F64 V66 V283 D287 S293 C294F64-A290 HydrophobicContact CD1-CB 3.79Å; F64-A290 HydrophobicContact CE1-CB 3.84Å; V66-A290 HydrophobicContact CB-CB 4.26Å; V66-A290 HydrophobicContact CG2-CB 3.85Å; V283-A290 HydrophobicContact CG2-CB 3.54Å; D287-A290 HydrophobicContact CB-CB 3.51Å; D287-A290 CarbonylContact O-C 3.53Å; D287-A290 WeakPolarHBondContact O-CA 3.42Å; D287-A290 PolarHBondContact O-N 2.95Å; D287-A290 PolarHBondContact OD1-N 3.33Å; A290-S293 PolarHBondContact O-N 3.21Å; A290-C294 VanDerWaalsContact O-CB 3.31Å; A290-C294 WeakPolarHBondContact O-CB 3.41Å; A290-C294 PolarHBondContact O-N 2.7Å; A290-C294 PolarHBondContact O-SG 3.41Å
291I97.4Very high97.1Very high0 Ų024.7 Ų24.70%012%0.117CC..Hα-helixtrans-57.3-51.9174.6-66.2-50.4000110.3S129 F248 V283 D287 S293 C294 V295 A312S129-I291 VanDerWaalsContact N-CG2 3.33Å; F248-I291 HydrophobicContact CE2-CD1 4.44Å; F248-I291 HydrophobicContact CE2-CG2 4.03Å; F248-I291 HydrophobicContact CZ-CD1 3.93Å; F248-I291 HydrophobicContact CZ-CG2 3.96Å; V283-I291 HydrophobicContact CB-CD1 4.29Å; V283-I291 HydrophobicContact CG1-CD1 3.4Å; V283-I291 HydrophobicContact CG2-CD1 3.88Å; D287-I291 WeakPolarHBondContact O-CG1 3.4Å; D287-I291 PolarHBondContact O-N 3.14Å; I291-S293 PolarHBondContact O-N 2.81Å; I291-C294 PolarHBondContact O-N 3.49Å; I291-V295 HydrophobicContact CG2-CG2 4.47Å; I291-V295 WeakPolarHBondContact O-CG2 3.39Å; I291-V295 PolarHBondContact O-N 3.16Å; I291-A312 HydrophobicContact CD1-CB 3.9Å
292Y96.7Very high97.1Very high41 Ų4121.9 Ų21.916%0.16110%0.103CC..Hα-helixtrans-55.8-51.1178.1177.4-91.9000111.5I80 L86 M90 A131 A132 I288 C294 V295 E296I80-Y292 HydrophobicContact CD1-CD1 4.05Å; I80-Y292 HydrophobicContact CD1-CE1 4.14Å; L86-Y292 HydrophobicContact CD2-CD2 4.41Å; L86-Y292 HydrophobicContact CD2-CE1 4.36Å; L86-Y292 HydrophobicContact CD2-CE2 3.82Å; M90-Y292 HydrophobicContact CE-CD2 3.46Å; M90-Y292 VanDerWaalsContact CE-CD2 3.46Å; M90-Y292 HydrophobicContact CE-CE2 4.11Å; M90-Y292 HydrophobicContact CE-CG 3.96Å; A131-Y292 HydrophobicContact CB-CD2 3.86Å; A131-Y292 HydrophobicContact CB-CE2 4.12Å; A131-Y292 WeakPolarHBondContact O-CE2 3.23Å; A132-Y292 HydrophobicContact CB-CD2 3.76Å; A132-Y292 HydrophobicContact CB-CE2 4.02Å; A132-Y292 HydrophobicContact CB-CG 4.3Å; A132-Y292 WeakPolarHBondContact CB-O 3.38Å; I288-Y292 WeakPolarHBondContact O-CB 3.5Å; I288-Y292 PolarHBondContact O-N 2.98Å; Y292-C294 PolarHBondContact O-N 3.27Å; Y292-V295 PolarHBondContact O-N 3.33Å; Y292-E296 WeakPolarHBondContact O-CB 3.29Å; Y292-E296 PolarHBondContact O-N 3.2Å
293S94.5Very high97Very high20 Ų2023.9 Ų23.914%0.1411%0.114CC..Hα-helixtrans-60.5-45.2-178.8-53.80000112.2I80 F289 A290 I291 H297I80-S293 WeakPolarHBondContact CD1-OG 3.21Å; F289-S293 WeakPolarHBondContact O-CB 3.27Å; F289-S293 PolarHBondContact O-N 2.7Å; F289-S293 PolarHBondContact O-OG 3.49Å; A290-S293 PolarHBondContact O-N 3.21Å; I291-S293 PolarHBondContact O-N 2.81Å; S293-H297 WeakPolarHBondContact O-CB 3.42Å; S293-H297 PolarHBondContact O-N 2.99Å
294C95.6Very high97Very high8 Ų829.8 Ų29.85%0.05414%0.142CC..Hα-helixtrans-64.4-44.6179.9-74.80000111.9F64 A290 I291 Y292 H297 A298 I310F64-C294 WeakPolarHBondContact CD1-SG 3.43Å; A290-C294 VanDerWaalsContact O-CB 3.31Å; A290-C294 WeakPolarHBondContact O-CB 3.41Å; A290-C294 PolarHBondContact O-N 2.7Å; A290-C294 PolarHBondContact O-SG 3.41Å; I291-C294 PolarHBondContact O-N 3.49Å; Y292-C294 PolarHBondContact O-N 3.27Å; C294-H297 PolarHBondContact O-N 3.39Å; C294-A298 VanDerWaalsContact O-CB 3.23Å; C294-A298 WeakPolarHBondContact O-CB 3.35Å; C294-A298 PolarHBondContact O-N 3.35Å; C294-I310 HydrophobicContact CB-CD1 4.29Å
295V98Very high96.9Very high0 Ų029.5 Ų29.50%014%0.143CC..Hα-helixtrans-70.4-38.6-179175.50000111A132 L133 L218 F248 I291 Y292 H297 A298 R299 I310A132-V295 HydrophobicContact CB-CB 3.73Å; A132-V295 HydrophobicContact CB-CG1 3.72Å; L133-V295 HydrophobicContact CD2-CG1 4.04Å; L133-V295 HydrophobicContact CG-CG1 4.33Å; L218-V295 HydrophobicContact CD1-CG1 3.92Å; F248-V295 HydrophobicContact CD2-CG2 3.85Å; F248-V295 HydrophobicContact CE2-CG2 3.63Å; I291-V295 HydrophobicContact CG2-CG2 4.47Å; I291-V295 WeakPolarHBondContact O-CG2 3.39Å; I291-V295 PolarHBondContact O-N 3.16Å; Y292-V295 PolarHBondContact O-N 3.33Å; V295-H297 VanDerWaalsContact C-N 3.31Å; V295-H297 PolarHBondContact O-N 2.97Å; V295-A298 PolarHBondContact O-N 2.9Å; V295-R299 WeakPolarHBondContact O-CB 3.26Å; V295-R299 PolarHBondContact O-N 2.91Å; V295-I310 HydrophobicContact CB-CD1 4.46Å; V295-I310 HydrophobicContact CG2-CD1 3.68Å
296E96.2Very high96.9Very high61 Ų6133.9 Ų33.929%0.28516%0.164SC..Hα-helixtrans-61.2-43175.6-164.6-149.7-13500110.7A132 Y292 K300A132-E296 HydrophobicContact CB-CB 4.11Å; Y292-E296 WeakPolarHBondContact O-CB 3.29Å; Y292-E296 PolarHBondContact O-N 3.2Å; E296-K300 WeakPolarHBondContact O-CG 3.29Å; E296-K300 PolarHBondContact O-N 3.37Å; E296-K300 IonicContact OE1-NZ 2.74Å; E296-K300 IonicContact OE2-NZ 2.74Å; E296-K300 PolarHBondContact OE2-NZ 3.48Å
297H96.6Very high96.9Very high108 Ų10833.8 Ų33.850%0.516%0.163SC..Hα-helixtrans-68.5-44.4176.1-167.877.8000112.3S293 C294 V295 R299 K300 L301S293-H297 WeakPolarHBondContact O-CB 3.42Å; S293-H297 PolarHBondContact O-N 2.99Å; C294-H297 PolarHBondContact O-N 3.39Å; V295-H297 VanDerWaalsContact C-N 3.31Å; V295-H297 PolarHBondContact O-N 2.97Å; H297-R299 VanDerWaalsContact C-N 3.28Å; H297-R299 PolarHBondContact O-N 3.06Å; H297-K300 WeakPolarHBondContact O-CB 3.45Å; H297-K300 PolarHBondContact O-N 3.45Å; H297-K300 VanDerWaalsContact O-N 3.09Å; H297-L301 PolarHBondContact O-N 3.11Å; H297-L301 VanDerWaalsContact O-N 3.09Å
298A98.4Very high97.1Very high5 Ų533.9 Ų33.94%0.04116%0.164CC..Hα-helixtrans-61.3-36.1177.500000112.2I246 C294 V295 K300 L301 A302 C308 I310I246-A298 HydrophobicContact CD1-CB 4.07Å; I246-A298 HydrophobicContact CG1-CB 4.23Å; I246-A298 HydrophobicContact CG2-CB 4.12Å; C294-A298 VanDerWaalsContact O-CB 3.23Å; C294-A298 WeakPolarHBondContact O-CB 3.35Å; C294-A298 PolarHBondContact O-N 3.35Å; V295-A298 PolarHBondContact O-N 2.9Å; A298-K300 VanDerWaalsContact C-N 3.34Å; A298-K300 PolarHBondContact O-N 2.99Å; A298-L301 PolarHBondContact O-N 3.03Å; A298-A302 VanDerWaalsContact O-CB 3.25Å; A298-A302 WeakPolarHBondContact O-CB 3.48Å; A298-A302 PolarHBondContact O-N 3.47Å; A298-C308 HydrophobicContact CB-CB 3.83Å; A298-C308 PolarHBondContact O-SG 3.37Å; A298-I310 HydrophobicContact CB-CD1 3.8Å; A298-I310 HydrophobicContact CB-CG1 4.44Å
299R98.2Very high97.2Very high30 Ų3033.8 Ų33.811%0.11316%0.164CC..Hα-helixtrans-58.2-46.5172.5-174.1-178-175.5-77.1-10.4111.5Q134 D137 D214 V216 I246 V295 H297 L301 A302 L303Q134-R299 VanDerWaalsContact CG-CZ 3.43Å; D137-R299 IonicContact OD1-NE 3.69Å; D137-R299 IonicContact OD1-NH2 2.72Å; D137-R299 PolarHBondContact OD1-NH2 2.83Å; D137-R299 IonicContact OD2-CZ 2.83Å; D137-R299 IonicContact OD2-NE 3.66Å; D137-R299 PolarHBondContact OD2-NE 3.27Å; D137-R299 IonicContact OD2-NH2 3.51Å; D214-R299 PolarHBondContact O-NH2 3.47Å; D214-R299 IonicContact OD1-NH2 2.74Å; V216-R299 HydrophobicContact CG1-CG 4Å; V216-R299 HydrophobicContact CG2-CG 3.96Å; I246-R299 HydrophobicContact CD1-CB 4.08Å; V295-R299 WeakPolarHBondContact O-CB 3.26Å; V295-R299 PolarHBondContact O-N 2.91Å; H297-R299 VanDerWaalsContact C-N 3.28Å; H297-R299 PolarHBondContact O-N 3.06Å; R299-L301 PolarHBondContact O-N 2.76Å; R299-A302 PolarHBondContact O-N 2.83Å; R299-L303 HydrophobicContact CG-CD1 4.18Å; R299-L303 WeakPolarHBondContact O-CD1 3.46Å; R299-L303 VanDerWaalsContact O-CG 3.28Å; R299-L303 WeakPolarHBondContact O-CG 3.45Å; R299-L303 PolarHBondContact O-N 2.78Å; R299-L303 VanDerWaalsContact O-N 3.11Å
300K97.8Very high97.4Very high100 Ų10033.4 Ų33.444%0.43516%0.162SC..Hα-helixtrans-60.4-44.2177.8-65.4165.1-177.1163.20111.4E296 H297 A298 Q304E296-K300 WeakPolarHBondContact O-CG 3.29Å; E296-K300 PolarHBondContact O-N 3.37Å; E296-K300 IonicContact OE1-NZ 2.74Å; E296-K300 IonicContact OE2-NZ 2.74Å; E296-K300 PolarHBondContact OE2-NZ 3.48Å; H297-K300 WeakPolarHBondContact O-CB 3.45Å; H297-K300 PolarHBondContact O-N 3.45Å; H297-K300 VanDerWaalsContact O-N 3.09Å; A298-K300 VanDerWaalsContact C-N 3.34Å; A298-K300 PolarHBondContact O-N 2.99Å; K300-Q304 WeakPolarHBondContact O-CG 3.48Å; K300-Q304 PolarHBondContact O-N 3.09Å
301L98.2Very high97.5Very high36 Ų3633.4 Ų33.419%0.18816%0.162CC..Hα-helixtrans-67.4-45.1177.9-65.8178.9000112.7A279 H297 A298 R299 L303 Q304 G305 Q306A279-L301 HydrophobicContact CB-CD1 4.25Å; H297-L301 PolarHBondContact O-N 3.11Å; H297-L301 VanDerWaalsContact O-N 3.09Å; A298-L301 PolarHBondContact O-N 3.03Å; R299-L301 PolarHBondContact O-N 2.76Å; L301-L303 VanDerWaalsContact C-N 3.31Å; L301-L303 PolarHBondContact O-N 3.25Å; L301-Q304 CarbonylContact O-C 3.54Å; L301-Q304 WeakPolarHBondContact O-CA 3.41Å; L301-Q304 WeakPolarHBondContact O-CB 3.46Å; L301-Q304 PolarHBondContact O-N 2.88Å; L301-G305 PolarHBondContact O-N 2.99Å; L301-Q306 CarbonylContact C-O 3.36Å; L301-Q306 HydrophobicContact CB-CB 4.31Å; L301-Q306 WeakPolarHBondContact O-CB 3.4Å; L301-Q306 PolarHBondContact O-N 3.39Å; L301-Q306 VanDerWaalsContact O-N 3.13Å
302A98.4Very high97.6Very high0 Ų033.4 Ų33.40%016%0.162CC..Hα-helixtrans-57.9-43.7178.900000111.6V216 P244 I246 A298 R299 Q304 G305 Q306V216-A302 HydrophobicContact CG1-CB 3.88Å; P244-A302 VanDerWaalsContact CA-O 3.26Å; P244-A302 WeakPolarHBondContact CA-O 3.33Å; P244-A302 WeakPolarHBondContact CB-O 3.38Å; I246-A302 HydrophobicContact CG1-CB 4.06Å; A298-A302 VanDerWaalsContact O-CB 3.25Å; A298-A302 WeakPolarHBondContact O-CB 3.48Å; A298-A302 PolarHBondContact O-N 3.47Å; R299-A302 PolarHBondContact O-N 2.83Å; A302-Q304 PolarHBondContact O-N 3.33Å; A302-G305 WeakPolarHBondContact O-CA 3.46Å; A302-G305 PolarHBondContact O-N 3.04Å; A302-Q306 VanDerWaalsContact CA-O 3.23Å; A302-Q306 WeakPolarHBondContact CA-O 3.38Å; A302-Q306 PolarHBondContact N-O 3.37Å
303L97.7Very high97.7Very high57 Ų5733.7 Ų33.730%0.29817%0.165SC..Hα-helixtrans-62.2-25.4175.4-69.5166.8000113.5D214 V216 R299 L301 G305D214-L303 WeakPolarHBondContact OD1-CD1 3.36Å; D214-L303 VanDerWaalsContact OD1-CD2 3.31Å; D214-L303 WeakPolarHBondContact OD1-CD2 3.41Å; V216-L303 HydrophobicContact CG1-CD1 4.48Å; V216-L303 HydrophobicContact CG1-CD2 3.74Å; V216-L303 HydrophobicContact CG1-CG 3.68Å; R299-L303 HydrophobicContact CG-CD1 4.18Å; R299-L303 WeakPolarHBondContact O-CD1 3.46Å; R299-L303 VanDerWaalsContact O-CG 3.28Å; R299-L303 WeakPolarHBondContact O-CG 3.45Å; R299-L303 PolarHBondContact O-N 2.78Å; R299-L303 VanDerWaalsContact O-N 3.11Å; L301-L303 VanDerWaalsContact C-N 3.31Å; L301-L303 PolarHBondContact O-N 3.25Å; L303-G305 PolarHBondContact O-N 3.49Å
304Q96.9Very high97.8Very high124 Ų12433 Ų3358%0.57916%0.16SC*.THydrogen-bonded Turntrans-83.57.7173.7-63.2170.22.700113K300 L301 A302K300-Q304 WeakPolarHBondContact O-CG 3.48Å; K300-Q304 PolarHBondContact O-N 3.09Å; L301-Q304 CarbonylContact O-C 3.54Å; L301-Q304 WeakPolarHBondContact O-CA 3.41Å; L301-Q304 WeakPolarHBondContact O-CB 3.46Å; L301-Q304 PolarHBondContact O-N 2.88Å; A302-Q304 PolarHBondContact O-N 3.33Å
305G96Very high97.8Very high13 Ų1332.8 Ų32.813%0.13416%0.158CC..THydrogen-bonded Turntrans75.930.5-17900000113.1R242 L301 A302 L303R242-G305 WeakPolarHBondContact CB-O 3.34Å; R242-G305 PolarHBondContact NE-O 3.15Å; L301-G305 PolarHBondContact O-N 2.99Å; A302-G305 WeakPolarHBondContact O-CA 3.46Å; A302-G305 PolarHBondContact O-N 3.04Å; L303-G305 PolarHBondContact O-N 3.49Å
306Q97.4Very high97.8Very high91 Ų9132.9 Ų32.943%0.42516%0.159SC..  trans-113.194.1169.9-62-173.910.500109.2L301 A302 C308L301-Q306 CarbonylContact C-O 3.36Å; L301-Q306 HydrophobicContact CB-CB 4.31Å; L301-Q306 WeakPolarHBondContact O-CB 3.4Å; L301-Q306 PolarHBondContact O-N 3.39Å; L301-Q306 VanDerWaalsContact O-N 3.13Å; A302-Q306 VanDerWaalsContact CA-O 3.23Å; A302-Q306 WeakPolarHBondContact CA-O 3.38Å; A302-Q306 PolarHBondContact N-O 3.37Å; Q306-C308 PolarHBondContact O-SG 2.91Å; Q306-C308 VanDerWaalsContact O-SG 3.34Å
307P98.5Very high97.7Very high4 Ų430.9 Ų30.93%0.02615%0.15CC..  trans-60.3140.3177.228.2-37.7000110.8A238 V245 L278 A279A238-P307 HydrophobicContact CB-CB 3.95Å; A238-P307 HydrophobicContact CB-CG 4.3Å; V245-P307 HydrophobicContact CG1-CB 3.79Å; V245-P307 WeakPolarHBondContact O-CA 3.3Å; L278-P307 HydrophobicContact CD2-CB 3.87Å; L278-P307 HydrophobicContact CD2-CG 3.54Å; A279-P307 PolarHBondContact N-O 3.47Å
308C98.8Very high97.5Very high2 Ų226.3 Ų26.31%0.01413%0.132CC..EExtended strand (participates in β ladder)trans-112148-172.3-61.80000112.5V245 I246 F247 A279 A298 Q306V245-C308 PolarHBondContact O-N 2.81Å; I246-C308 HydrophobicContact CG2-CB 4.39Å; F247-C308 WeakPolarHBondContact CB-O 3.35Å; F247-C308 WeakPolarHBondContact CD2-O 3.1Å; F247-C308 PolarHBondContact N-O 3.47Å; A279-C308 CarbonylContact O-C 3.57Å; A279-C308 WeakPolarHBondContact O-CA 3.31Å; A298-C308 HydrophobicContact CB-CB 3.83Å; A298-C308 PolarHBondContact O-SG 3.37Å; Q306-C308 PolarHBondContact O-SG 2.91Å; Q306-C308 VanDerWaalsContact O-SG 3.34Å
309L98.9Very high97.4Very high0 Ų028.6 Ų28.60%014%0.142CC..EExtended strand (participates in β ladder)trans-121.9120167.5175.262.9000109.6F221 F235 F247 V269 L278 A279 T280 I281F221-L309 HydrophobicContact CZ-CD1 3.92Å; F235-L309 HydrophobicContact CE1-CD1 4.31Å; F235-L309 HydrophobicContact CE2-CD2 4.41Å; F235-L309 HydrophobicContact CZ-CD1 3.96Å; F235-L309 HydrophobicContact CZ-CD2 4.29Å; F247-L309 HydrophobicContact CB-CD1 3.77Å; F247-L309 WeakPolarHBondContact O-CA 3.42Å; V269-L309 HydrophobicContact CG1-CD1 4.31Å; V269-L309 HydrophobicContact CG1-CD2 4.34Å; V269-L309 WeakPolarHBondContact O-CD2 3.38Å; L278-L309 HydrophobicContact CB-CB 4.35Å; L278-L309 HydrophobicContact CD1-CB 4.12Å; A279-L309 PolarHBondContact O-N 3.05Å; T280-L309 CarbonylContact C-O 3.59Å; T280-L309 VanDerWaalsContact CA-O 3.29Å; T280-L309 WeakPolarHBondContact CA-O 3.48Å; T280-L309 HydrophobicContact CG2-CB 4.17Å; T280-L309 HydrophobicContact CG2-CD2 4.06Å; T280-L309 HydrophobicContact CG2-CG 4.19Å; I281-L309 PolarHBondContact N-O 2.65Å
310I98.9Very high97.4Very high1 Ų128.5 Ų28.51%0.00514%0.143CC..EExtended strand (participates in β ladder)trans-111.3120.5173.2-58.6174.4000107.4I246 F247 F248 C249 I281 V283 C294 V295 A298I246-I310 HydrophobicContact CG2-CD1 3.92Å; I246-I310 HydrophobicContact CG2-CG1 4.4Å; F247-I310 PolarHBondContact O-N 3.05Å; F248-I310 HydrophobicContact CD2-CB 4.14Å; F248-I310 HydrophobicContact CD2-CD1 4.22Å; F248-I310 HydrophobicContact CD2-CG2 4.1Å; F248-I310 HydrophobicContact CE2-CG2 3.97Å; C249-I310 PolarHBondContact N-O 3.32Å; I281-I310 HydrophobicContact CG2-CB 4.35Å; I281-I310 HydrophobicContact CG2-CG1 3.86Å; I281-I310 HydrophobicContact CG2-CG2 4.33Å; I281-I310 WeakPolarHBondContact O-CA 3.35Å; V283-I310 HydrophobicContact CG1-CG2 3.57Å; C294-I310 HydrophobicContact CB-CD1 4.29Å; V295-I310 HydrophobicContact CB-CD1 4.46Å; V295-I310 HydrophobicContact CG2-CD1 3.68Å; A298-I310 HydrophobicContact CB-CD1 3.8Å; A298-I310 HydrophobicContact CB-CG1 4.44Å
311E98.9Very high97.3Very high0 Ų024.1 Ų24.10%013%0.125CC..EExtended strand (participates in β ladder)trans-101.6107.1168.8-172.6179.6-146.300109.6C249 N251 V269 A270 I281 R282 V283 M313C249-E311 HydrophobicContact CB-CG 4.47Å; N251-E311 HydrophobicContact CB-CG 3.98Å; N251-E311 PolarHBondContact ND2-OE1 2.8Å; V269-E311 HydrophobicContact CB-CG 4.44Å; V269-E311 PolarHBondContact N-OE1 3.41Å; A270-E311 HydrophobicContact CB-CB 3.83Å; A270-E311 WeakPolarHBondContact CB-OE2 3.48Å; A270-E311 PolarHBondContact N-OE2 3.18Å; I281-E311 PolarHBondContact O-N 3.44Å; R282-E311 CarbonylContact C-O 3.51Å; R282-E311 WeakPolarHBondContact CA-O 3.41Å; R282-E311 HydrophobicContact CG-CB 4.46Å; R282-E311 IonicContact CZ-OE2 2.86Å; R282-E311 IonicContact NE-OE2 3.84Å; R282-E311 PolarHBondContact NE-OE2 2.85Å; R282-E311 IonicContact NH2-OE2 3.21Å; R282-E311 PolarHBondContact NH2-OE2 3.28Å; V283-E311 PolarHBondContact N-O 3.35Å; E311-M313 HydrophobicContact CG-SD 3.69Å
312A98.7Very high97.3Very high0 Ų022.6 Ų22.60%012%0.117CC..EExtended strand (participates in β ladder)trans-89.5113.217600000110.2F248 C249 N251 V283 I291 T314F248-A312 HydrophobicContact CE1-CB 3.66Å; F248-A312 HydrophobicContact CZ-CB 3.75Å; C249-A312 PolarHBondContact O-N 3.21Å; N251-A312 PolarHBondContact N-O 2.91Å; V283-A312 HydrophobicContact CG1-CB 4Å; V283-A312 WeakPolarHBondContact O-CA 3.3Å; I291-A312 HydrophobicContact CD1-CB 3.9Å; A312-T314 PolarHBondContact O-N 3.45Å
313M98.3Very high97.1Very high47 Ų4727.4 Ų27.423%0.23215%0.15CC..EExtended strand (participates in β ladder)trans-82.7108180-53.3-52.3-61.500109.7I63 N251 R282 V283 G285 E311I63-M313 HydrophobicContact CD1-CG 4.06Å; I63-M313 HydrophobicContact CG1-CG 4.25Å; N251-M313 HydrophobicContact CB-CE 4.13Å; N251-M313 HydrophobicContact CB-SD 3.98Å; R282-M313 HydrophobicContact CG-CG 3.55Å; R282-M313 HydrophobicContact CG-SD 3.81Å; V283-M313 PolarHBondContact O-N 3.47Å; G285-M313 VanDerWaalsContact CA-O 3.27Å; G285-M313 WeakPolarHBondContact CA-O 3.48Å; G285-M313 PolarHBondContact N-O 2.78Å; E311-M313 HydrophobicContact CG-SD 3.69Å
314T97.4Very high97.1Very high6 Ų625.9 Ų25.94%0.03714%0.143CC..  trans-135.1-169.9-178.1-174.80000110G121 E122 N251 N252 N286 A312G121-T314 PolarHBondContact O-OG1 3.37Å; E122-T314 HydrophobicContact CG-CG2 3.93Å; N251-T314 PolarHBondContact O-N 3.29Å; N252-T314 WeakPolarHBondContact CA-O 3.48Å; N252-T314 HydrophobicContact CB-CG2 3.75Å; N286-T314 PolarHBondContact OD1-OG1 3.06Å; A312-T314 PolarHBondContact O-N 3.45Å
315Y96.8Very high97Very high3 Ų324 Ų241%0.01214%0.137CC..  trans-143.2129.6176.7-174.6-93.9000110.7A253 Y254 L317 E334 V335 W338A253-Y315 HydrophobicContact CB-CD2 4.41Å; Y254-Y315 HydrophobicContact CD2-CE2 4.43Å; Y254-Y315 HydrophobicContact CE2-CE2 4.1Å; Y315-L317 HydrophobicContact CD1-CD2 3.78Å; Y315-L317 HydrophobicContact CD1-CG 4.24Å; Y315-L317 HydrophobicContact CE1-CD2 4.18Å; Y315-L317 PolarHBondContact O-N 2.76Å; Y315-E334 HydrophobicContact CE2-CG 4.17Å; Y315-E334 VanDerWaalsContact CE2-OE1 3.27Å; Y315-E334 WeakPolarHBondContact CE2-OE1 3.3Å; Y315-E334 PolarHBondContact OH-OE1 2.87Å; Y315-V335 HydrophobicContact CE1-CG2 4.34Å; Y315-V335 WeakPolarHBondContact OH-CG2 3.32Å; Y315-W338 HydrophobicContact CD1-CB 3.48Å; Y315-W338 VanDerWaalsContact CD1-CB 3.48Å; Y315-W338 AromaticContact CD1-CD1 3.68Å; Y315-W338 HydrophobicContact CD1-CD2 4.22Å; Y315-W338 AromaticContact CD1-CG 3.52Å; Y315-W338 HydrophobicContact CD1-CG 3.52Å; Y315-W338 AromaticContact CD2-CD1 3.34Å; Y315-W338 AromaticContact CD2-CD2 3.93Å; Y315-W338 HydrophobicContact CD2-CD2 3.93Å; Y315-W338 AromaticContact CD2-CE2 3.66Å; Y315-W338 AromaticContact CD2-CG 3.76Å; Y315-W338 HydrophobicContact CD2-CG 3.76Å; Y315-W338 HydrophobicContact CD2-CZ2 4.38Å; Y315-W338 AromaticContact CD2-NE1 3.28Å; Y315-W338 VanDerWaalsContact CD2-NE1 3.28Å; Y315-W338 HydrophobicContact CE1-CB 3.99Å; Y315-W338 AromaticContact CE1-CD1 3.81Å; Y315-W338 HydrophobicContact CE1-CG 4.05Å; Y315-W338 AromaticContact CE2-CD1 3.5Å; Y315-W338 VanDerWaalsContact CE2-CD1 3.5Å; Y315-W338 HydrophobicContact CE2-CG 4.26Å; Y315-W338 AromaticContact CE2-NE1 3.61Å; Y315-W338 HydrophobicContact CG-CB 3.82Å; Y315-W338 AromaticContact CG-CD1 3.42Å; Y315-W338 VanDerWaalsContact CG-CD1 3.42Å; Y315-W338 AromaticContact CG-CD2 3.58Å; Y315-W338 HydrophobicContact CG-CD2 3.58Å; Y315-W338 AromaticContact CG-CE2 3.84Å; Y315-W338 HydrophobicContact CG-CE3 4.25Å; Y315-W338 AromaticContact CG-CG 3.33Å; Y315-W338 HydrophobicContact CG-CG 3.33Å; Y315-W338 AromaticContact CG-NE1 3.72Å; Y315-W338 AromaticContact CZ-CD1 3.72Å
316R96.2Very high97Very high3 Ų323.8 Ų23.81%0.01113%0.133CC..  trans-74.693.8179-168.2-17675.2-151.57.3110.1N252 Y254 I256 G318 D324 Y329 R330N252-R316 HydrophobicContact CB-CB 4.07Å; N252-R316 PolarHBondContact O-N 3.22Å; Y254-R316 PolarHBondContact O-NH1 3.37Å; I256-R316 PolarHBondContact O-NH1 3.46Å; I256-R316 PolarHBondContact O-NH2 3.43Å; R316-G318 PolarHBondContact O-N 2.95Å; R316-D324 IonicContact NH2-OD2 2.69Å; R316-Y329 PolarHBondContact NH2-OH 3.3Å; R316-R330 PolarHBondContact O-NH1 2.65Å
317L94.3Very high96.8Very high18 Ų1823.9 Ų23.99%0.09414%0.14CC..  trans-67.6-38.6-176.5-71.5172.3000112.5L120 Y315 W338L120-L317 HydrophobicContact CB-CB 4.22Å; L120-L317 HydrophobicContact CD2-CB 3.7Å; L120-L317 HydrophobicContact CG-CB 3.72Å; L120-L317 HydrophobicContact CG-CD1 4.08Å; L120-L317 WeakPolarHBondContact O-CB 3.38Å; L120-L317 PolarHBondContact O-N 3.46Å; Y315-L317 HydrophobicContact CD1-CD2 3.78Å; Y315-L317 HydrophobicContact CD1-CG 4.24Å; Y315-L317 HydrophobicContact CE1-CD2 4.18Å; Y315-L317 PolarHBondContact O-N 2.76Å; L317-W338 HydrophobicContact CD2-CB 3.76Å
318G93.3Very high96.7Very high13 Ų1327.8 Ų27.813%0.13417%0.173CC..SBendtrans-75.1174175.800000113.8R316 R330R316-G318 PolarHBondContact O-N 2.95Å; G318-R330 PolarHBondContact O-NH2 3.35Å
319H96.2Very high96.6Very high53 Ų5330.5 Ų30.525%0.24518%0.183CC..  trans-61.3165.5164-55.3-53.1000110.9Y105 S321 D324 D325 S326Y105-H319 PolarHBondContact OH-CD2 2.86Å; H319-S321 VanDerWaalsContact C-N 3.35Å; H319-D324 HydrophobicContact CB-CB 4.4Å; H319-D325 IonicContact CE1-OD1 3.49Å; H319-S326 WeakPolarHBondContact ND1-CB 3.35Å; H319-S326 PolarHBondContact ND1-N 2.79Å; H319-S326 VanDerWaalsContact ND1-N 3.11Å; H319-S326 PolarHBondContact ND1-OG 3.04Å
320H97.2Very high96.3Very high27 Ų2730.9 Ų30.913%0.12518%0.184CC..SBendtrans-59.5-48.7174.6178.675.1000110.9M117 R144 D324M117-H320 WeakPolarHBondContact CE-O 3.25Å; R144-H320 PolarHBondContact NH1-O 3.45Å; R144-H320 PolarHBondContact NH2-ND1 3.05Å; R144-H320 PolarHBondContact NH2-O 2.86Å; H320-D324 HydrophobicContact CB-CB 3.75Å; H320-D324 VanDerWaalsContact CB-OD2 3.29Å; H320-D324 WeakPolarHBondContact CB-OD2 3.45Å; H320-D324 PolarHBondContact N-OD2 3.2Å
321S97.3Very high96Very high9 Ų936.7 Ų36.76%0.06322%0.215CC..SBendtrans-153.7-178.1174.669.70000109.2F115 H319 S323 D324F115-S321 VanDerWaalsContact CE2-CB 3.45Å; H319-S321 VanDerWaalsContact C-N 3.35Å; S321-S323 PolarHBondContact O-N 3.06Å; S321-S323 VanDerWaalsContact O-N 3.16Å; S321-S323 PolarHBondContact OG-N 3.1Å; S321-D324 PolarHBondContact O-N 3.35Å; S321-D324 VanDerWaalsContact O-N 3.11Å
322T96.6Very high95.7Very high4 Ų441.4 Ų41.43%0.02525%0.246CC..THydrogen-bonded Turntrans-60.8-16.2168.249.50000113.9Y105 Q108 R109 Y116Y105-T322 HydrophobicContact CD2-CG2 3.61Å; Y105-T322 HydrophobicContact CE2-CG2 3.6Å; Y105-T322 HydrophobicContact CG-CG2 4.49Å; Q108-T322 HydrophobicContact CB-CG2 3.91Å; Q108-T322 HydrophobicContact CG-CG2 3.69Å; R109-T322 VanDerWaalsContact CZ-O 3.28Å; R109-T322 PolarHBondContact NH1-O 2.88Å; R109-T322 PolarHBondContact NH2-O 3.04Å; Y116-T322 PolarHBondContact N-OG1 3.49Å; Y116-T322 VanDerWaalsContact N-OG1 3.08Å; Y116-T322 WeakPolarHBondContact O-CG2 3.5Å; Y116-T322 PolarHBondContact O-N 3.01Å; Y116-T322 PolarHBondContact O-OG1 2.86Å
323S95.8Very high95.4Very high100 Ų10050.1 Ų50.170%0.69928%0.284SS*.THydrogen-bonded Turntrans-92.94.1177.1-51.80000113.4S321S321-S323 PolarHBondContact O-N 3.06Å; S321-S323 VanDerWaalsContact O-N 3.16Å; S321-S323 PolarHBondContact OG-N 3.1Å
324D96.1Very high95.2Very high25 Ų2550.6 Ų50.613%0.13429%0.285CS..  trans-118143.7-176.4174.256000111.2R316 H319 H320 S321 Y329R316-D324 IonicContact NH2-OD2 2.69Å; H319-D324 HydrophobicContact CB-CB 4.4Å; H320-D324 HydrophobicContact CB-CB 3.75Å; H320-D324 VanDerWaalsContact CB-OD2 3.29Å; H320-D324 WeakPolarHBondContact CB-OD2 3.45Å; H320-D324 PolarHBondContact N-OD2 3.2Å; S321-D324 PolarHBondContact O-N 3.35Å; S321-D324 VanDerWaalsContact O-N 3.11Å; D324-Y329 VanDerWaalsContact CG-OH 3.31Å; D324-Y329 VanDerWaalsContact OD1-CE1 3.29Å; D324-Y329 WeakPolarHBondContact OD1-CE1 3.14Å; D324-Y329 PolarHBondContact OD1-OH 3.41Å; D324-Y329 PolarHBondContact OD2-OH 2.79Å
325D95.5Very high94.9Very high86 Ų8652 Ų5246%0.4629%0.294SS..  trans-119.6100.3166.4-178.3-4000109H319 T327 A328H319-D325 IonicContact CE1-OD1 3.49Å; D325-T327 VanDerWaalsContact CG-OG1 3.27Å; D325-T327 PolarHBondContact O-N 2.97Å; D325-T327 WeakPolarHBondContact OD1-CB 2.95Å; D325-T327 WeakPolarHBondContact OD1-CG2 3.44Å; D325-T327 PolarHBondContact OD1-N 3.26Å; D325-T327 PolarHBondContact OD1-OG1 2.74Å; D325-T327 PolarHBondContact OD2-OG1 3.26Å; D325-A328 WeakPolarHBondContact O-CB 3.2Å; D325-A328 PolarHBondContact O-N 3.01Å
326S95.4Very high94.7Very high8 Ų853.7 Ų53.76%0.05631%0.308CS..G310 helixtrans-71.5-10.1-176.775.40000115.4H319 A328 Y329 R330H319-S326 WeakPolarHBondContact ND1-CB 3.35Å; H319-S326 PolarHBondContact ND1-N 2.79Å; H319-S326 VanDerWaalsContact ND1-N 3.11Å; H319-S326 PolarHBondContact ND1-OG 3.04Å; S326-A328 PolarHBondContact O-N 3.32Å; S326-Y329 VanDerWaalsContact CA-CE1 3.49Å; S326-Y329 VanDerWaalsContact CA-CZ 3.47Å; S326-Y329 WeakPolarHBondContact CA-OH 3.44Å; S326-Y329 WeakPolarHBondContact CB-OH 3.41Å; S326-Y329 PolarHBondContact O-N 3.04Å; S326-R330 PolarHBondContact O-N 3.04Å; S326-R330 VanDerWaalsContact O-N 3.09Å; S326-R330 PolarHBondContact OG-NH2 2.85Å
327T93.8Very high94.5Very high92 Ų9258.7 Ų58.756%0.56433%0.33SS*.G310 helixtrans-69.7-16.8175.468.60000111.9D325 Y329D325-T327 VanDerWaalsContact CG-OG1 3.27Å; D325-T327 PolarHBondContact O-N 2.97Å; D325-T327 WeakPolarHBondContact OD1-CB 2.95Å; D325-T327 WeakPolarHBondContact OD1-CG2 3.44Å; D325-T327 PolarHBondContact OD1-N 3.26Å; D325-T327 PolarHBondContact OD1-OG1 2.74Å; D325-T327 PolarHBondContact OD2-OG1 3.26Å; T327-Y329 VanDerWaalsContact C-N 3.34Å; T327-Y329 PolarHBondContact O-N 3.48Å
328A96Very high94.4Very high87 Ų8761 Ų6172%0.71934%0.338SS*.G310 helixtrans-72.3-21.5177.400000114.3D325 S326D325-A328 WeakPolarHBondContact O-CB 3.2Å; D325-A328 PolarHBondContact O-N 3.01Å; S326-A328 PolarHBondContact O-N 3.32Å
329Y95.9Very high94.2Very high59 Ų5963.3 Ų63.323%0.23135%0.352CS..THydrogen-bonded Turntrans-139-1.7-173.858.6-95.9000114.8Y254 I256 R316 D324 S326 T327Y254-Y329 HydrophobicContact CD1-CD2 4.27Å; Y254-Y329 HydrophobicContact CD1-CE2 4.19Å; Y254-Y329 HydrophobicContact CE1-CD2 4.21Å; Y254-Y329 HydrophobicContact CE1-CE2 4.49Å; I256-Y329 VanDerWaalsContact O-CE2 3.26Å; I256-Y329 WeakPolarHBondContact O-CE2 3.21Å; I256-Y329 VanDerWaalsContact O-CZ 3.22Å; I256-Y329 PolarHBondContact O-OH 2.85Å; R316-Y329 PolarHBondContact NH2-OH 3.3Å; D324-Y329 VanDerWaalsContact CG-OH 3.31Å; D324-Y329 VanDerWaalsContact OD1-CE1 3.29Å; D324-Y329 WeakPolarHBondContact OD1-CE1 3.14Å; D324-Y329 PolarHBondContact OD1-OH 3.41Å; D324-Y329 PolarHBondContact OD2-OH 2.79Å; S326-Y329 VanDerWaalsContact CA-CE1 3.49Å; S326-Y329 VanDerWaalsContact CA-CZ 3.47Å; S326-Y329 WeakPolarHBondContact CA-OH 3.44Å; S326-Y329 WeakPolarHBondContact CB-OH 3.41Å; S326-Y329 PolarHBondContact O-N 3.04Å; T327-Y329 VanDerWaalsContact C-N 3.34Å; T327-Y329 PolarHBondContact O-N 3.48Å
330R93.9Very high93.7Very high7 Ų768.1 Ų68.13%0.02637%0.374CS..SBendtrans-122.7143.4174.4-55.6-170.4-66.6-175.6-1.1111.4Y254 R316 G318 S326Y254-R330 HydrophobicContact CD1-CG 4.38Å; Y254-R330 HydrophobicContact CE1-CG 3.81Å; Y254-R330 VanDerWaalsContact CE2-CD 3.47Å; Y254-R330 HydrophobicContact CE2-CG 4.04Å; R316-R330 PolarHBondContact O-NH1 2.65Å; G318-R330 PolarHBondContact O-NH2 3.35Å; S326-R330 PolarHBondContact O-N 3.04Å; S326-R330 VanDerWaalsContact O-N 3.09Å; S326-R330 PolarHBondContact OG-NH2 2.85Å
331L92.7Very high93Very high124 Ų12471.5 Ų71.565%0.64939%0.393SS*.  trans-75.2131.1178.6-64.2175.9000110.2K333 E334 V335L331-K333 PolarHBondContact O-N 3.03Å; L331-K333 VanDerWaalsContact O-N 3.11Å; L331-E334 HydrophobicContact CB-CB 4.39Å; L331-E334 WeakPolarHBondContact O-CB 3.34Å; L331-E334 PolarHBondContact O-N 3.16Å; L331-V335 PolarHBondContact O-N 3.34Å
332P91.4Very high92.3Very high99 Ų9973 Ų7364%0.64340%0.4SS*.Hα-helixtrans-55.6-32.2177.1-29.135.6000114.1E334 V335 A336P332-E334 VanDerWaalsContact C-N 3.34Å; P332-E334 PolarHBondContact O-N 2.65Å; P332-V335 PolarHBondContact O-N 3.36Å; P332-A336 WeakPolarHBondContact O-CB 3.19Å; P332-A336 PolarHBondContact O-N 3.27Å
333K93.5Very high92.1Very high183 Ų18373.7 Ų73.780%0.79641%0.405SS*.Hα-helixtrans-63.3-37.4176.4-70.6-175.6178179.70112.7L331 F337L331-K333 PolarHBondContact O-N 3.03Å; L331-K333 VanDerWaalsContact O-N 3.11Å; K333-F337 WeakPolarHBondContact O-CB 3.42Å; K333-F337 PolarHBondContact O-N 3.2Å
334E93.1Very high92.1Very high56 Ų5669 Ų6926%0.26237%0.372SS..Hα-helixtrans-66.8-48.4178-177.5-172.916600110.5Y254 Y315 L331 P332 A336 F337 W338Y254-E334 PolarHBondContact OH-OE1 3.11Å; Y254-E334 PolarHBondContact OH-OE2 3.11Å; Y315-E334 HydrophobicContact CE2-CG 4.17Å; Y315-E334 VanDerWaalsContact CE2-OE1 3.27Å; Y315-E334 WeakPolarHBondContact CE2-OE1 3.3Å; Y315-E334 PolarHBondContact OH-OE1 2.87Å; L331-E334 HydrophobicContact CB-CB 4.39Å; L331-E334 WeakPolarHBondContact O-CB 3.34Å; L331-E334 PolarHBondContact O-N 3.16Å; P332-E334 VanDerWaalsContact C-N 3.34Å; P332-E334 PolarHBondContact O-N 2.65Å; E334-A336 VanDerWaalsContact C-N 3.31Å; E334-A336 PolarHBondContact O-N 2.94Å; E334-F337 WeakPolarHBondContact O-CB 3.21Å; E334-F337 PolarHBondContact O-N 2.66Å; E334-W338 VanDerWaalsContact O-CD1 3.27Å; E334-W338 PolarHBondContact O-N 3.25Å; E334-W338 VanDerWaalsContact O-N 3.16Å
335V92.6Very high92Very high37 Ų3768 Ų6822%0.22437%0.367CS..Hα-helixtrans-60.3-42.9177-178.90000111Y315 L331 P332 W338 S339Y315-V335 HydrophobicContact CE1-CG2 4.34Å; Y315-V335 WeakPolarHBondContact OH-CG2 3.32Å; L331-V335 PolarHBondContact O-N 3.34Å; P332-V335 PolarHBondContact O-N 3.36Å; V335-W338 PolarHBondContact O-N 3.24Å; V335-S339 VanDerWaalsContact O-CB 3.3Å; V335-S339 WeakPolarHBondContact O-CB 3.43Å; V335-S339 PolarHBondContact O-N 3.13Å
336A92.1Very high92Very high38 Ų3866 Ų6631%0.31436%0.36SS..Hα-helixtrans-62.7-41.5177.100000112.4P332 E334 W338 S339 Q340P332-A336 WeakPolarHBondContact O-CB 3.19Å; P332-A336 PolarHBondContact O-N 3.27Å; E334-A336 VanDerWaalsContact C-N 3.31Å; E334-A336 PolarHBondContact O-N 2.94Å; A336-W338 PolarHBondContact O-N 2.72Å; A336-S339 PolarHBondContact O-N 3.33Å; A336-Q340 WeakPolarHBondContact O-CB 3.46Å; A336-Q340 VanDerWaalsContact O-CG 3.31Å; A336-Q340 WeakPolarHBondContact O-CG 3.05Å; A336-Q340 PolarHBondContact O-N 3.4Å
337F92Very high92Very high107 Ų10766 Ų6647%0.46936%0.358SS..Hα-helixtrans-57-49.7176.1172.4-91.8000111.6K333 E334 L341K333-F337 WeakPolarHBondContact O-CB 3.42Å; K333-F337 PolarHBondContact O-N 3.2Å; E334-F337 WeakPolarHBondContact O-CB 3.21Å; E334-F337 PolarHBondContact O-N 2.66Å; F337-L341 HydrophobicContact CD2-CD1 3.56Å; F337-L341 HydrophobicContact CE2-CD1 3.46Å; F337-L341 VanDerWaalsContact CE2-CD1 3.46Å; F337-L341 HydrophobicContact CG-CD1 4.39Å; F337-L341 HydrophobicContact CZ-CD1 4.24Å; F337-L341 WeakPolarHBondContact O-CB 3.38Å; F337-L341 PolarHBondContact O-N 3.01Å
338W92.1Very high92Very high68 Ų6861.6 Ų61.626%0.25833%0.331SS..Hα-helixtrans-67.2-42.9178.8-75.6103.6000112.7Y315 L317 E334 V335 A336 Q340 N342 S343Y315-W338 HydrophobicContact CD1-CB 3.48Å; Y315-W338 VanDerWaalsContact CD1-CB 3.48Å; Y315-W338 AromaticContact CD1-CD1 3.68Å; Y315-W338 HydrophobicContact CD1-CD2 4.22Å; Y315-W338 AromaticContact CD1-CG 3.52Å; Y315-W338 HydrophobicContact CD1-CG 3.52Å; Y315-W338 AromaticContact CD2-CD1 3.34Å; Y315-W338 AromaticContact CD2-CD2 3.93Å; Y315-W338 HydrophobicContact CD2-CD2 3.93Å; Y315-W338 AromaticContact CD2-CE2 3.66Å; Y315-W338 AromaticContact CD2-CG 3.76Å; Y315-W338 HydrophobicContact CD2-CG 3.76Å; Y315-W338 HydrophobicContact CD2-CZ2 4.38Å; Y315-W338 AromaticContact CD2-NE1 3.28Å; Y315-W338 VanDerWaalsContact CD2-NE1 3.28Å; Y315-W338 HydrophobicContact CE1-CB 3.99Å; Y315-W338 AromaticContact CE1-CD1 3.81Å; Y315-W338 HydrophobicContact CE1-CG 4.05Å; Y315-W338 AromaticContact CE2-CD1 3.5Å; Y315-W338 VanDerWaalsContact CE2-CD1 3.5Å; Y315-W338 HydrophobicContact CE2-CG 4.26Å; Y315-W338 AromaticContact CE2-NE1 3.61Å; Y315-W338 HydrophobicContact CG-CB 3.82Å; Y315-W338 AromaticContact CG-CD1 3.42Å; Y315-W338 VanDerWaalsContact CG-CD1 3.42Å; Y315-W338 AromaticContact CG-CD2 3.58Å; Y315-W338 HydrophobicContact CG-CD2 3.58Å; Y315-W338 AromaticContact CG-CE2 3.84Å; Y315-W338 HydrophobicContact CG-CE3 4.25Å; Y315-W338 AromaticContact CG-CG 3.33Å; Y315-W338 HydrophobicContact CG-CG 3.33Å; Y315-W338 AromaticContact CG-NE1 3.72Å; Y315-W338 AromaticContact CZ-CD1 3.72Å; L317-W338 HydrophobicContact CD2-CB 3.76Å; E334-W338 VanDerWaalsContact O-CD1 3.27Å; E334-W338 PolarHBondContact O-N 3.25Å; E334-W338 VanDerWaalsContact O-N 3.16Å; V335-W338 PolarHBondContact O-N 3.24Å; A336-W338 PolarHBondContact O-N 2.72Å; W338-Q340 PolarHBondContact O-N 3.04Å; W338-N342 HydrophobicContact CE3-CB 3.61Å; W338-N342 HydrophobicContact CZ3-CB 3.99Å; W338-N342 CarbonylContact O-C 3.45Å; W338-N342 WeakPolarHBondContact O-CA 3.44Å; W338-N342 PolarHBondContact O-N 3.42Å; W338-S343 PolarHBondContact O-N 3.38Å
339S88.9Confident92.1Very high60 Ų6060.2 Ų60.242%0.4231%0.308SS..Hα-helixtrans-61.7-42.4-179.4-172.80000112.2V335 A336V335-S339 VanDerWaalsContact O-CB 3.3Å; V335-S339 WeakPolarHBondContact O-CB 3.43Å; V335-S339 PolarHBondContact O-N 3.13Å; A336-S339 PolarHBondContact O-N 3.33Å
340Q86.3Confident92Very high155 Ų15559.3 Ų59.372%0.72431%0.31SS*.Hα-helixtrans-82.4-41.1-175.2-68.6177.5-3.700113.4A336 W338A336-Q340 WeakPolarHBondContact O-CB 3.46Å; A336-Q340 VanDerWaalsContact O-CG 3.31Å; A336-Q340 WeakPolarHBondContact O-CG 3.05Å; A336-Q340 PolarHBondContact O-N 3.4Å; W338-Q340 PolarHBondContact O-N 3.04Å
341L81.3Confident92.1Very high97 Ų9759.4 Ų59.451%0.50831%0.311SS..Hα-helixtrans-101.5-22.6-168.5-62.7174.4000114F337F337-L341 HydrophobicContact CD2-CD1 3.56Å; F337-L341 HydrophobicContact CE2-CD1 3.46Å; F337-L341 VanDerWaalsContact CE2-CD1 3.46Å; F337-L341 HydrophobicContact CG-CD1 4.39Å; F337-L341 HydrophobicContact CZ-CD1 4.24Å; F337-L341 WeakPolarHBondContact O-CB 3.38Å; F337-L341 PolarHBondContact O-N 3.01Å
342N83.5Confident92.2Very high41 Ų4153.6 Ų53.622%0.21928%0.28CS..  trans-133.119.2-166.9-66.1-66.9000113.6N286 W338N286-N342 WeakPolarHBondContact CB-O 3.5Å; N286-N342 PolarHBondContact ND2-O 3.19Å; N286-N342 VanDerWaalsContact ND2-O 3.11Å; W338-N342 HydrophobicContact CE3-CB 3.61Å; W338-N342 HydrophobicContact CZ3-CB 3.99Å; W338-N342 CarbonylContact O-C 3.45Å; W338-N342 WeakPolarHBondContact O-CA 3.44Å; W338-N342 PolarHBondContact O-N 3.42Å
343S91.2Very high92.4Very high19 Ų1952.1 Ų52.113%0.13327%0.266CS..  trans-64125.4174.7169.80000111.1W338 L345 S346 R347W338-S343 PolarHBondContact O-N 3.38Å; S343-L345 VanDerWaalsContact C-N 3.29Å; S343-L345 PolarHBondContact O-N 2.73Å; S343-S346 PolarHBondContact O-N 2.96Å; S343-S346 PolarHBondContact OG-N 2.91Å; S343-R347 WeakPolarHBondContact O-CB 3.31Å; S343-R347 PolarHBondContact O-N 3.46Å
344P95.8Very high92.4Very high1 Ų146.9 Ų46.91%0.00624%0.244CC..Hα-helixtrans-59.9-39.6178.322.8-33.3000112.3M94 E123 A124 N286 R347 L348M94-P344 HydrophobicContact CE-CB 3.69Å; M94-P344 HydrophobicContact CE-CG 4.15Å; E123-P344 WeakPolarHBondContact OE2-CG 3.38Å; A124-P344 HydrophobicContact CB-CB 3.49Å; A124-P344 VanDerWaalsContact CB-CB 3.49Å; A124-P344 HydrophobicContact CB-CG 4.45Å; N286-P344 HydrophobicContact CB-CB 4.21Å; P344-R347 PolarHBondContact O-N 2.93Å; P344-L348 PolarHBondContact O-N 3Å; P344-L348 VanDerWaalsContact O-N 3.07Å
345L95.2Very high92.4Very high5 Ų549.6 Ų49.63%0.02626%0.256CS..Hα-helixtrans-64.8-47.2179.4-176.769.8000111.1F91 M94 I95 S343 R347 L348 R349F91-L345 HydrophobicContact CD2-CD1 3.68Å; F91-L345 HydrophobicContact CE2-CD1 3.38Å; F91-L345 HydrophobicContact CE2-CG 4.07Å; F91-L345 HydrophobicContact CZ-CD1 4.27Å; M94-L345 HydrophobicContact CB-CD1 3.69Å; M94-L345 HydrophobicContact CE-CB 4.04Å; M94-L345 HydrophobicContact CE-CD1 4.35Å; I95-L345 HydrophobicContact CG1-CD1 3.85Å; S343-L345 VanDerWaalsContact C-N 3.29Å; S343-L345 PolarHBondContact O-N 2.73Å; L345-R347 PolarHBondContact O-N 2.74Å; L345-L348 PolarHBondContact O-N 3.41Å; L345-R349 VanDerWaalsContact O-CB 3.3Å; L345-R349 WeakPolarHBondContact O-CB 3.45Å; L345-R349 PolarHBondContact O-N 2.84Å
346S94.3Very high92.5Very high44 Ų4456.7 Ų56.731%0.30828%0.284SS..Hα-helixtrans-62.8-32178-62.90000113.2S343 R349 S350S343-S346 PolarHBondContact O-N 2.96Å; S343-S346 PolarHBondContact OG-N 2.91Å; S346-R349 VanDerWaalsContact CA-NH1 3.29Å; S346-R349 PolarHBondContact OG-NH1 2.97Å; S346-S350 WeakPolarHBondContact O-CB 3.36Å; S346-S350 PolarHBondContact O-N 3.47Å; S346-S350 PolarHBondContact O-OG 3.44Å
347R95.3Very high92.6Very high6 Ų657.9 Ų57.92%0.02329%0.285CS..Hα-helixtrans-71.3-47178.2-153171.870.113650.2112.2M67 N68 D284 N286 D287 S343 P344 L345 S350 F351M67-R347 HydrophobicContact CE-CB 4.38Å; M67-R347 HydrophobicContact CE-CG 3.89Å; M67-R347 PolarHBondContact O-NH1 3.09Å; M67-R347 PolarHBondContact O-NH2 3.25Å; N68-R347 WeakPolarHBondContact O-CD 3.37Å; N68-R347 WeakPolarHBondContact O-CG 3.5Å; D284-R347 IonicContact OD1-NH1 3.07Å; D284-R347 IonicContact OD2-CZ 2.91Å; D284-R347 IonicContact OD2-NH1 3.65Å; D284-R347 PolarHBondContact OD2-NH1 3.42Å; N286-R347 PolarHBondContact O-NE 2.88Å; D287-R347 VanDerWaalsContact CB-CZ 3.47Å; D287-R347 VanDerWaalsContact N-NH1 3.19Å; D287-R347 IonicContact OD1-NH2 2.76Å; D287-R347 PolarHBondContact OD1-NH2 3.42Å; D287-R347 IonicContact OD2-NH2 3.45Å; D287-R347 PolarHBondContact OD2-NH2 2.94Å; D287-R347 VanDerWaalsContact OD2-NH2 3.07Å; S343-R347 WeakPolarHBondContact O-CB 3.31Å; S343-R347 PolarHBondContact O-N 3.46Å; P344-R347 PolarHBondContact O-N 2.93Å; L345-R347 PolarHBondContact O-N 2.74Å; R347-S350 PolarHBondContact O-N 3.13Å; R347-F351 PolarHBondContact O-N 3.24Å
348L95.7Very high92.8Very high0 Ų053.5 Ų53.50%027%0.266CS..Hα-helixtrans-66.8-38.2174.7-176.358.1000111.8M90 F91 M94 I288 F289 P344 L345 S350 F351 L352M90-L348 HydrophobicContact CB-CD2 4.24Å; F91-L348 HydrophobicContact CB-CD2 3.63Å; F91-L348 HydrophobicContact CB-CG 4.14Å; F91-L348 HydrophobicContact CD2-CB 4.17Å; F91-L348 HydrophobicContact CD2-CD2 3.91Å; F91-L348 HydrophobicContact CD2-CG 3.9Å; F91-L348 HydrophobicContact CG-CD2 4.25Å; F91-L348 HydrophobicContact CG-CG 4.39Å; M94-L348 HydrophobicContact SD-CD2 3.81Å; I288-L348 HydrophobicContact CD1-CD2 4.21Å; I288-L348 HydrophobicContact CG2-CD1 4.07Å; I288-L348 HydrophobicContact CG2-CD2 4.16Å; I288-L348 HydrophobicContact CG2-CG 4.49Å; F289-L348 HydrophobicContact CE1-CD1 4.39Å; F289-L348 HydrophobicContact CE2-CD1 4.2Å; F289-L348 HydrophobicContact CZ-CD1 3.71Å; P344-L348 PolarHBondContact O-N 3Å; P344-L348 VanDerWaalsContact O-N 3.07Å; L345-L348 PolarHBondContact O-N 3.41Å; L348-S350 VanDerWaalsContact C-N 3.32Å; L348-S350 PolarHBondContact O-N 2.79Å; L348-F351 HydrophobicContact CD1-CD1 4.1Å; L348-F351 WeakPolarHBondContact O-CB 3.36Å; L348-F351 PolarHBondContact O-N 3.49Å; L348-L352 HydrophobicContact CD1-CG 4.31Å; L348-L352 HydrophobicContact CG-CD1 4.2Å; L348-L352 HydrophobicContact CG-CG 4.42Å; L348-L352 WeakPolarHBondContact O-CG 3.47Å; L348-L352 PolarHBondContact O-N 3.32Å
349R96.3Very high93Very high58 Ų5853 Ų5322%0.21927%0.27CS..Hα-helixtrans-54-49.8172-177.4-172.2-62.6112.26111.1F91 L345 S346 F351 L352 L353 E363F91-R349 HydrophobicContact CE2-CB 3.68Å; F91-R349 HydrophobicContact CE2-CG 4.44Å; F91-R349 HydrophobicContact CZ-CB 3.72Å; F91-R349 HydrophobicContact CZ-CG 3.98Å; L345-R349 VanDerWaalsContact O-CB 3.3Å; L345-R349 WeakPolarHBondContact O-CB 3.45Å; L345-R349 PolarHBondContact O-N 2.84Å; S346-R349 VanDerWaalsContact CA-NH1 3.29Å; S346-R349 PolarHBondContact OG-NH1 2.97Å; R349-F351 VanDerWaalsContact C-N 3.3Å; R349-F351 PolarHBondContact O-N 3.01Å; R349-L352 PolarHBondContact O-N 3.02Å; R349-L353 HydrophobicContact CG-CD1 3.88Å; R349-L353 HydrophobicContact CG-CG 4.32Å; R349-L353 WeakPolarHBondContact O-CB 3.4Å; R349-L353 WeakPolarHBondContact O-CG 3.42Å; R349-L353 PolarHBondContact O-N 3.29Å; R349-E363 WeakPolarHBondContact CD-OE2 3.41Å; R349-E363 WeakPolarHBondContact CG-OE2 3.29Å; R349-E363 IonicContact CZ-OE1 2.66Å; R349-E363 IonicContact CZ-OE2 2.96Å; R349-E363 IonicContact NE-OE1 2.68Å; R349-E363 PolarHBondContact NE-OE1 3.16Å; R349-E363 IonicContact NE-OE2 3.67Å; R349-E363 PolarHBondContact NE-OE2 2.82Å; R349-E363 IonicContact NH2-OE1 3.75Å; R349-E363 PolarHBondContact NH2-OE1 3.42Å
350S95.1Very high93.3Very high41 Ų4152.9 Ų52.929%0.28727%0.27SS..Hα-helixtrans-62.3-37.6-178.5-65.40000112.1S70 S346 R347 L348 K354S70-S350 WeakPolarHBondContact O-CB 3.42Å; S346-S350 WeakPolarHBondContact O-CB 3.36Å; S346-S350 PolarHBondContact O-N 3.47Å; S346-S350 PolarHBondContact O-OG 3.44Å; R347-S350 PolarHBondContact O-N 3.13Å; L348-S350 VanDerWaalsContact C-N 3.32Å; L348-S350 PolarHBondContact O-N 2.79Å; S350-K354 WeakPolarHBondContact O-CB 3.44Å; S350-K354 WeakPolarHBondContact O-CD 3.49Å; S350-K354 WeakPolarHBondContact O-CG 3.48Å; S350-K354 PolarHBondContact O-N 3.2Å
351F94.7Very high93.8Very high9 Ų952.3 Ų52.34%0.03927%0.267CS..Hα-helixtrans-63.5-52.1171.9171.1-97.8000112M67 L73 I82 A87 F289 R347 L348 R349 L353 K354 E355 L357M67-F351 HydrophobicContact SD-CB 3.6Å; M67-F351 VanDerWaalsContact SD-CB 3.6Å; M67-F351 HydrophobicContact SD-CD2 4.13Å; M67-F351 HydrophobicContact SD-CG 4.02Å; L73-F351 HydrophobicContact CD1-CE2 4.03Å; L73-F351 HydrophobicContact CD2-CD2 4.36Å; L73-F351 HydrophobicContact CD2-CE2 4.05Å; L73-F351 HydrophobicContact CG-CD2 4.46Å; L73-F351 HydrophobicContact CG-CE2 4.01Å; I82-F351 HydrophobicContact CD1-CE2 4.46Å; I82-F351 HydrophobicContact CD1-CZ 4.15Å; I82-F351 HydrophobicContact CG2-CE1 4.24Å; I82-F351 HydrophobicContact CG2-CZ 4.17Å; A87-F351 HydrophobicContact CB-CE1 4.32Å; F289-F351 AromaticContact CE2-CD1 3.74Å; F289-F351 HydrophobicContact CE2-CD1 3.74Å; F289-F351 HydrophobicContact CE2-CD2 4.15Å; F289-F351 AromaticContact CE2-CE1 3.76Å; F289-F351 HydrophobicContact CE2-CE1 3.76Å; F289-F351 HydrophobicContact CE2-CE2 4.16Å; F289-F351 AromaticContact CE2-CG 3.94Å; F289-F351 HydrophobicContact CE2-CG 3.94Å; F289-F351 AromaticContact CE2-CZ 3.97Å; F289-F351 HydrophobicContact CE2-CZ 3.97Å; F289-F351 AromaticContact CZ-CD1 3.71Å; F289-F351 HydrophobicContact CZ-CD1 3.71Å; F289-F351 AromaticContact CZ-CE1 3.51Å; F289-F351 HydrophobicContact CZ-CE1 3.51Å; F289-F351 HydrophobicContact CZ-CG 4.38Å; F289-F351 HydrophobicContact CZ-CZ 4.04Å; R347-F351 PolarHBondContact O-N 3.24Å; L348-F351 HydrophobicContact CD1-CD1 4.1Å; L348-F351 WeakPolarHBondContact O-CB 3.36Å; L348-F351 PolarHBondContact O-N 3.49Å; R349-F351 VanDerWaalsContact C-N 3.3Å; R349-F351 PolarHBondContact O-N 3.01Å; F351-L353 PolarHBondContact O-N 2.95Å; F351-K354 PolarHBondContact O-N 3.45Å; F351-E355 HydrophobicContact CD2-CG 4.13Å; F351-E355 HydrophobicContact CE1-CG 4.3Å; F351-E355 HydrophobicContact CE2-CG 3.71Å; F351-E355 HydrophobicContact CZ-CG 3.82Å; F351-E355 WeakPolarHBondContact O-CG 3.32Å; F351-E355 PolarHBondContact O-N 2.85Å; F351-L357 HydrophobicContact CE1-CD1 4.42Å
352L96.2Very high94.6Very high1 Ų152.2 Ų52.21%0.00526%0.264CS..Hα-helixtrans-62.9-39.1-177.2-68.3176000113.2A87 I88 F91 L348 R349 K356 L357 F358A87-L352 HydrophobicContact CB-CD2 3.92Å; I88-L352 HydrophobicContact CG1-CD2 4.26Å; F91-L352 HydrophobicContact CB-CD1 3.45Å; F91-L352 VanDerWaalsContact CB-CD1 3.45Å; F91-L352 HydrophobicContact CD1-CD1 3.49Å; F91-L352 VanDerWaalsContact CD1-CD1 3.49Å; F91-L352 HydrophobicContact CD2-CD1 4.03Å; F91-L352 HydrophobicContact CE1-CD1 4.19Å; F91-L352 HydrophobicContact CG-CD1 3.39Å; L348-L352 HydrophobicContact CD1-CG 4.31Å; L348-L352 HydrophobicContact CG-CD1 4.2Å; L348-L352 HydrophobicContact CG-CG 4.42Å; L348-L352 WeakPolarHBondContact O-CG 3.47Å; L348-L352 PolarHBondContact O-N 3.32Å; R349-L352 PolarHBondContact O-N 3.02Å; L352-K356 PolarHBondContact O-N 3.05Å; L352-L357 HydrophobicContact CD2-CB 3.84Å; L352-L357 HydrophobicContact CD2-CD1 3.93Å; L352-L357 PolarHBondContact O-N 3.31Å; L352-F358 HydrophobicContact CB-CB 3.89Å; L352-F358 HydrophobicContact CD1-CB 4.26Å
353L95.7Very high95.3Very high68 Ų6851.6 Ų51.636%0.35626%0.26SS..Hα-helixtrans-63.4-41.2175.4-72.2173.2000111.6R349 F351 K356 F358R349-L353 HydrophobicContact CG-CD1 3.88Å; R349-L353 HydrophobicContact CG-CG 4.32Å; R349-L353 WeakPolarHBondContact O-CB 3.4Å; R349-L353 WeakPolarHBondContact O-CG 3.42Å; R349-L353 PolarHBondContact O-N 3.29Å; F351-L353 PolarHBondContact O-N 2.95Å; L353-K356 PolarHBondContact O-N 2.8Å; L353-F358 WeakPolarHBondContact CD2-O 3.15Å
354K93Very high95.5Very high74 Ų7454.6 Ų54.632%0.32228%0.281SS..Hα-helixtrans-68.3-42.5179.4-76.1171.1179.8175.60112.6S70 Y72 S350 F351 K356S70-K354 PolarHBondContact O-NZ 2.99Å; Y72-K354 HydrophobicContact CD1-CD 4.21Å; Y72-K354 HydrophobicContact CE1-CD 3.82Å; Y72-K354 PolarHBondContact OH-NZ 3.29Å; S350-K354 WeakPolarHBondContact O-CB 3.44Å; S350-K354 WeakPolarHBondContact O-CD 3.49Å; S350-K354 WeakPolarHBondContact O-CG 3.48Å; S350-K354 PolarHBondContact O-N 3.2Å; F351-K354 PolarHBondContact O-N 3.45Å; K354-K356 PolarHBondContact O-N 3.22Å
355E92.7Very high95.6Very high112 Ų11261 Ų6152%0.52331%0.309SS..THydrogen-bonded Turntrans-77.2-0.5175.9-61.7-57.1134.900112.5F351 L357F351-E355 HydrophobicContact CD2-CG 4.13Å; F351-E355 HydrophobicContact CE1-CG 4.3Å; F351-E355 HydrophobicContact CE2-CG 3.71Å; F351-E355 HydrophobicContact CZ-CG 3.82Å; F351-E355 WeakPolarHBondContact O-CG 3.32Å; F351-E355 PolarHBondContact O-N 2.85Å; E355-L357 HydrophobicContact CB-CD1 3.81Å; E355-L357 HydrophobicContact CB-CG 3.81Å; E355-L357 PolarHBondContact O-N 3.21Å
356K94.7Very high95.8Very high187 Ų18762 Ų6281%0.81331%0.314SS*.THydrogen-bonded Turntrans55.432.6-178.4-54.4177.8-178.7177.80113L352 L353 K354L352-K356 PolarHBondContact O-N 3.05Å; L353-K356 PolarHBondContact O-N 2.8Å; K354-K356 PolarHBondContact O-N 3.22Å
357L95.1Very high95.9Very high63 Ų6361.4 Ų61.433%0.3331%0.311SS..SBendtrans-89.1-14.9179.4-67.5175.8000112.6I88 F351 L352 E355I88-L357 HydrophobicContact CD1-CB 4.28Å; I88-L357 VanDerWaalsContact CD1-O 3.29Å; I88-L357 WeakPolarHBondContact CD1-O 3.3Å; I88-L357 HydrophobicContact CG1-CB 4.38Å; F351-L357 HydrophobicContact CE1-CD1 4.42Å; L352-L357 HydrophobicContact CD2-CB 3.84Å; L352-L357 HydrophobicContact CD2-CD1 3.93Å; L352-L357 PolarHBondContact O-N 3.31Å; E355-L357 HydrophobicContact CB-CD1 3.81Å; E355-L357 HydrophobicContact CB-CG 3.81Å; E355-L357 PolarHBondContact O-N 3.21Å
358F95.5Very high96.1Very high15 Ų1567.2 Ų67.27%0.06634%0.339CS..SBendtrans-155.3152.6-178.9-149.7-111.3000109.9I88 F91 L352 L353 E362 E363 L366I88-F358 HydrophobicContact CG2-CD2 4.32Å; I88-F358 HydrophobicContact CG2-CE2 4.36Å; F91-F358 AromaticContact CD1-CD1 3.87Å; F91-F358 HydrophobicContact CD1-CD1 3.87Å; F91-F358 AromaticContact CD1-CE1 3.88Å; F91-F358 HydrophobicContact CD1-CE1 3.88Å; F91-F358 HydrophobicContact CD1-CG 4.38Å; F91-F358 HydrophobicContact CD1-CZ 4.45Å; F91-F358 AromaticContact CE1-CD1 3.5Å; F91-F358 HydrophobicContact CE1-CD1 3.5Å; F91-F358 AromaticContact CE1-CE1 3.55Å; F91-F358 HydrophobicContact CE1-CE1 3.55Å; F91-F358 HydrophobicContact CE1-CG 4.38Å; F91-F358 HydrophobicContact CE1-CZ 4.5Å; L352-F358 HydrophobicContact CB-CB 3.89Å; L352-F358 HydrophobicContact CD1-CB 4.26Å; L353-F358 WeakPolarHBondContact CD2-O 3.15Å; F358-E362 WeakPolarHBondContact CA-OE2 3.45Å; F358-E362 HydrophobicContact CD1-CB 4.36Å; F358-E362 HydrophobicContact CD2-CB 4.45Å; F358-E362 HydrophobicContact CE1-CB 3.99Å; F358-E362 HydrophobicContact CE2-CB 4.06Å; F358-E362 HydrophobicContact CZ-CB 3.82Å; F358-E363 HydrophobicContact CD1-CB 4.22Å; F358-E363 HydrophobicContact CE1-CB 3.71Å; F358-E363 HydrophobicContact CE1-CG 4.48Å; F358-L366 HydrophobicContact CZ-CD2 4.12Å
359T96.8Very high96.2Very high56 Ų5670.8 Ų70.834%0.34436%0.357SS..  trans-115.3161.6175.5830000113.3E361 E362 E363T359-E361 VanDerWaalsContact C-N 3.26Å; T359-E361 WeakPolarHBondContact CB-OE2 3.36Å; T359-E361 PolarHBondContact O-N 3.17Å; T359-E361 PolarHBondContact OG1-N 2.94Å; T359-E361 PolarHBondContact OG1-OE2 3.35Å; T359-E362 PolarHBondContact N-OE2 3.46Å; T359-E362 PolarHBondContact O-N 3.4Å; T359-E362 WeakPolarHBondContact OG1-CG 3.3Å; T359-E362 PolarHBondContact OG1-N 3.28Å; T359-E362 VanDerWaalsContact OG1-N 3.13Å; T359-E363 PolarHBondContact O-N 3.28Å
360S95.6Very high96.3Very high59 Ų5970.1 Ų70.141%0.41336%0.355SS..Hα-helixtrans-63.8-32.5175.2-58.50000112.4S364S360-S364 WeakPolarHBondContact O-CB 3.44Å; S360-S364 PolarHBondContact O-N 3.4Å; S360-S364 PolarHBondContact O-OG 3.44Å
361E97.1Very high96.5Very high142 Ų14272.2 Ų72.266%0.66436%0.357SS*.Hα-helixtrans-69.2-43.5175.5-61.574.4-159.900111.4T359 E363 S364 K365T359-E361 VanDerWaalsContact C-N 3.26Å; T359-E361 WeakPolarHBondContact CB-OE2 3.36Å; T359-E361 PolarHBondContact O-N 3.17Å; T359-E361 PolarHBondContact OG1-N 2.94Å; T359-E361 PolarHBondContact OG1-OE2 3.35Å; E361-E363 VanDerWaalsContact C-N 3.32Å; E361-E363 PolarHBondContact O-N 2.75Å; E361-S364 PolarHBondContact O-N 2.93Å; E361-K365 WeakPolarHBondContact O-CB 2.98Å; E361-K365 PolarHBondContact O-N 3.37Å
362E97.5Very high96.7Very high96 Ų9674.7 Ų74.745%0.44938%0.375SS..Hα-helixtrans-61.1-42.2174.3-72178.2132.800111.2F358 T359 L366F358-E362 WeakPolarHBondContact CA-OE2 3.45Å; F358-E362 HydrophobicContact CD1-CB 4.36Å; F358-E362 HydrophobicContact CD2-CB 4.45Å; F358-E362 HydrophobicContact CE1-CB 3.99Å; F358-E362 HydrophobicContact CE2-CB 4.06Å; F358-E362 HydrophobicContact CZ-CB 3.82Å; T359-E362 PolarHBondContact N-OE2 3.46Å; T359-E362 PolarHBondContact O-N 3.4Å; T359-E362 WeakPolarHBondContact OG1-CG 3.3Å; T359-E362 PolarHBondContact OG1-N 3.28Å; T359-E362 VanDerWaalsContact OG1-N 3.13Å; E362-L366 WeakPolarHBondContact O-CB 3.23Å; E362-L366 PolarHBondContact O-N 2.99Å
363E97.3Very high96.8Very high27 Ų2777 Ų7713%0.12639%0.387CS..Hα-helixtrans-61.1-50.9175.6-175.7176.6176.700112.4F91 I95 R349 F358 T359 E361 K365 L366 A367F91-E363 HydrophobicContact CE1-CG 4.32Å; F91-E363 HydrophobicContact CZ-CG 4.34Å; I95-E363 HydrophobicContact CD1-CG 3.89Å; R349-E363 WeakPolarHBondContact CD-OE2 3.41Å; R349-E363 WeakPolarHBondContact CG-OE2 3.29Å; R349-E363 IonicContact CZ-OE1 2.66Å; R349-E363 IonicContact CZ-OE2 2.96Å; R349-E363 IonicContact NE-OE1 2.68Å; R349-E363 PolarHBondContact NE-OE1 3.16Å; R349-E363 IonicContact NE-OE2 3.67Å; R349-E363 PolarHBondContact NE-OE2 2.82Å; R349-E363 IonicContact NH2-OE1 3.75Å; R349-E363 PolarHBondContact NH2-OE1 3.42Å; F358-E363 HydrophobicContact CD1-CB 4.22Å; F358-E363 HydrophobicContact CE1-CB 3.71Å; F358-E363 HydrophobicContact CE1-CG 4.48Å; T359-E363 PolarHBondContact O-N 3.28Å; E361-E363 VanDerWaalsContact C-N 3.32Å; E361-E363 PolarHBondContact O-N 2.75Å; E363-K365 VanDerWaalsContact C-N 3.33Å; E363-K365 PolarHBondContact O-N 3.22Å; E363-L366 PolarHBondContact O-N 3.12Å; E363-A367 WeakPolarHBondContact O-CB 3.43Å; E363-A367 PolarHBondContact O-N 2.69Å
364S96.9Very high96.9Very high82 Ų8273.7 Ų73.757%0.57337%0.37SS*.Hα-helixtrans-61-44.1-177.5-60.40000111.3S360 E361 Q368S360-S364 WeakPolarHBondContact O-CB 3.44Å; S360-S364 PolarHBondContact O-N 3.4Å; S360-S364 PolarHBondContact O-OG 3.44Å; E361-S364 PolarHBondContact O-N 2.93Å; S364-Q368 PolarHBondContact O-N 3.17Å; S364-Q368 VanDerWaalsContact O-N 3.13Å
365K98Very high97.2Very high137 Ų13774.1 Ų74.160%0.59638%0.375SS*.Hα-helixtrans-62.5-48.1175.8-177.8176.7178.3-179.40111.5E361 E363 A367 Q368 D369E361-K365 WeakPolarHBondContact O-CB 2.98Å; E361-K365 PolarHBondContact O-N 3.37Å; E363-K365 VanDerWaalsContact C-N 3.33Å; E363-K365 PolarHBondContact O-N 3.22Å; K365-A367 VanDerWaalsContact C-N 3.35Å; K365-A367 PolarHBondContact O-N 3.23Å; K365-Q368 WeakPolarHBondContact O-CB 3.06Å; K365-Q368 PolarHBondContact O-N 3.19Å; K365-D369 PolarHBondContact O-N 2.63Å
366L98.1Very high97.5Very high26 Ų2675.5 Ų75.514%0.13638%0.376CS..Hα-helixtrans-61.2-43.1-179.5-17571.4000112.2K92 I95 F358 E362 E363 Q368 D369 Y370K92-L366 HydrophobicContact CB-CD2 4.15Å; K92-L366 HydrophobicContact CD-CD2 4.27Å; K92-L366 HydrophobicContact CG-CD2 3.63Å; I95-L366 HydrophobicContact CD1-CD2 4.02Å; F358-L366 HydrophobicContact CZ-CD2 4.12Å; E362-L366 WeakPolarHBondContact O-CB 3.23Å; E362-L366 PolarHBondContact O-N 2.99Å; E363-L366 PolarHBondContact O-N 3.12Å; L366-Q368 VanDerWaalsContact C-N 3.32Å; L366-Q368 PolarHBondContact O-N 2.91Å; L366-D369 PolarHBondContact O-N 3.34Å; L366-Y370 HydrophobicContact CD1-CD2 4.32Å; L366-Y370 HydrophobicContact CD1-CE1 4.02Å; L366-Y370 HydrophobicContact CD1-CE2 3.71Å; L366-Y370 HydrophobicContact CD2-CD2 4.47Å; L366-Y370 HydrophobicContact CD2-CE2 3.71Å; L366-Y370 HydrophobicContact CG-CD2 3.9Å; L366-Y370 HydrophobicContact CG-CE2 3.47Å; L366-Y370 VanDerWaalsContact CG-CE2 3.47Å; L366-Y370 PolarHBondContact O-N 2.94Å
367A97.7Very high97.6Very high30 Ų3066.9 Ų66.925%0.24834%0.339CS..Hα-helixtrans-61.2-41.8176.500000111.4I95 E363 K365 R371I95-A367 HydrophobicContact CG2-CB 3.96Å; E363-A367 WeakPolarHBondContact O-CB 3.43Å; E363-A367 PolarHBondContact O-N 2.69Å; K365-A367 VanDerWaalsContact C-N 3.35Å; K365-A367 PolarHBondContact O-N 3.23Å; A367-R371 WeakPolarHBondContact O-CG 3.31Å; A367-R371 PolarHBondContact O-N 3.5Å
368Q98.2Very high97.8Very high129 Ų12964 Ų6460%0.60332%0.324SS*.Hα-helixtrans-64.8-42.9176.4-175.1176.7700112.6S364 K365 L366 R371 S372S364-Q368 PolarHBondContact O-N 3.17Å; S364-Q368 VanDerWaalsContact O-N 3.13Å; K365-Q368 WeakPolarHBondContact O-CB 3.06Å; K365-Q368 PolarHBondContact O-N 3.19Å; L366-Q368 VanDerWaalsContact C-N 3.32Å; L366-Q368 PolarHBondContact O-N 2.91Å; Q368-R371 PolarHBondContact O-N 2.88Å; Q368-S372 PolarHBondContact O-N 3.44Å; Q368-S372 VanDerWaalsContact O-N 3.08Å; Q368-S372 PolarHBondContact O-OG 3.28Å
369D98.5Very high97.9Very high74 Ų7465.9 Ų65.940%0.39634%0.337SS..Hα-helixtrans-62.2-48.6178.2-70-18.8000110.4K365 L366 R371 S372 D373K365-D369 PolarHBondContact O-N 2.63Å; L366-D369 PolarHBondContact O-N 3.34Å; D369-R371 PolarHBondContact O-N 2.91Å; D369-S372 WeakPolarHBondContact O-CB 3.35Å; D369-S372 PolarHBondContact O-N 3.14Å; D369-S372 VanDerWaalsContact O-N 3.14Å; D369-D373 PolarHBondContact O-N 3.08Å
370Y98.6Very high97.9Very high44 Ų4466.9 Ų66.917%0.17334%0.339CS..Hα-helixtrans-62-42.4177.4-72.5-25.8000113.5K92 I95 F96 L366 S372 D373 V374K92-Y370 WeakPolarHBondContact O-CE2 3.39Å; I95-Y370 HydrophobicContact CB-CD2 4.49Å; I95-Y370 HydrophobicContact CB-CE2 4.49Å; I95-Y370 HydrophobicContact CG2-CD2 4.02Å; I95-Y370 HydrophobicContact CG2-CE2 4.43Å; F96-Y370 HydrophobicContact CB-CD2 3.72Å; F96-Y370 HydrophobicContact CB-CE2 3.61Å; F96-Y370 HydrophobicContact CB-CG 4.24Å; F96-Y370 AromaticContact CD2-CD1 3.86Å; F96-Y370 HydrophobicContact CD2-CD1 3.86Å; F96-Y370 HydrophobicContact CD2-CD2 4.08Å; F96-Y370 HydrophobicContact CD2-CE1 4.35Å; F96-Y370 AromaticContact CD2-CG 3.71Å; F96-Y370 HydrophobicContact CD2-CG 3.71Å; F96-Y370 HydrophobicContact CE2-CD1 4.3Å; F96-Y370 HydrophobicContact CE2-CG 4.47Å; F96-Y370 HydrophobicContact CG-CD1 4.35Å; F96-Y370 HydrophobicContact CG-CD2 4.25Å; F96-Y370 HydrophobicContact CG-CE1 4.41Å; F96-Y370 HydrophobicContact CG-CE2 4.3Å; F96-Y370 HydrophobicContact CG-CG 4.27Å; L366-Y370 HydrophobicContact CD1-CD2 4.32Å; L366-Y370 HydrophobicContact CD1-CE1 4.02Å; L366-Y370 HydrophobicContact CD1-CE2 3.71Å; L366-Y370 HydrophobicContact CD2-CD2 4.47Å; L366-Y370 HydrophobicContact CD2-CE2 3.71Å; L366-Y370 HydrophobicContact CG-CD2 3.9Å; L366-Y370 HydrophobicContact CG-CE2 3.47Å; L366-Y370 VanDerWaalsContact CG-CE2 3.47Å; L366-Y370 PolarHBondContact O-N 2.94Å; Y370-S372 VanDerWaalsContact C-N 3.27Å; Y370-S372 PolarHBondContact O-N 3.3Å; Y370-D373 PolarHBondContact O-N 3.45Å; Y370-V374 VanDerWaalsContact O-CG2 3.31Å; Y370-V374 WeakPolarHBondContact O-CG2 3.16Å; Y370-V374 PolarHBondContact O-N 2.93Å
371R98.5Very high98Very high86 Ų8664 Ų6433%0.32532%0.319SS..Hα-helixtrans-56.9-45173.6-70.9168.174.177.22.7111.4A99 E102 A367 Q368 D369 D373 V374 I375A99-R371 HydrophobicContact CB-CG 4.21Å; E102-R371 IonicContact OE1-CZ 2.79Å; E102-R371 VanDerWaalsContact OE1-CZ 3.25Å; E102-R371 IonicContact OE1-NH1 2.69Å; E102-R371 PolarHBondContact OE1-NH1 2.85Å; E102-R371 IonicContact OE1-NH2 3.42Å; E102-R371 PolarHBondContact OE1-NH2 2.96Å; E102-R371 IonicContact OE2-CZ 3.86Å; E102-R371 IonicContact OE2-NH1 2.75Å; E102-R371 PolarHBondContact OE2-NH1 3.14Å; A367-R371 WeakPolarHBondContact O-CG 3.31Å; A367-R371 PolarHBondContact O-N 3.5Å; Q368-R371 PolarHBondContact O-N 2.88Å; D369-R371 PolarHBondContact O-N 2.91Å; R371-D373 VanDerWaalsContact C-N 3.32Å; R371-D373 PolarHBondContact O-N 3.49Å; R371-V374 PolarHBondContact O-N 3.29Å; R371-I375 VanDerWaalsContact O-CG1 3.27Å; R371-I375 WeakPolarHBondContact O-CG1 3.41Å; R371-I375 PolarHBondContact O-N 3.29Å
372S98.5Very high97.9Very high60 Ų6060.5 Ų60.542%0.4230%0.303SS..Hα-helixtrans-62.6-40.5179.1-56.90000111.4Q368 D369 Y370 R376Q368-S372 PolarHBondContact O-N 3.44Å; Q368-S372 VanDerWaalsContact O-N 3.08Å; Q368-S372 PolarHBondContact O-OG 3.28Å; D369-S372 WeakPolarHBondContact O-CB 3.35Å; D369-S372 PolarHBondContact O-N 3.14Å; D369-S372 VanDerWaalsContact O-N 3.14Å; Y370-S372 VanDerWaalsContact C-N 3.27Å; Y370-S372 PolarHBondContact O-N 3.3Å; S372-R376 WeakPolarHBondContact O-CB 3.43Å; S372-R376 PolarHBondContact O-N 2.64Å
373D98.5Very high97.7Very high49 Ų4964.1 Ų64.126%0.26232%0.317SS..Hα-helixtrans-64.8-43.1176.4-72.7-19.7000112.6L156 D369 Y370 R371 R376 A377L156-D373 HydrophobicContact CD2-CB 4.09Å; D369-D373 PolarHBondContact O-N 3.08Å; Y370-D373 PolarHBondContact O-N 3.45Å; R371-D373 VanDerWaalsContact C-N 3.32Å; R371-D373 PolarHBondContact O-N 3.49Å; D373-R376 PolarHBondContact O-N 3.05Å; D373-R376 IonicContact OD1-CZ 3.58Å; D373-R376 IonicContact OD1-NH1 2.67Å; D373-R376 PolarHBondContact OD1-NH1 3.41Å; D373-R376 IonicContact OD1-NH2 2.93Å; D373-R376 PolarHBondContact OD1-NH2 2.99Å; D373-A377 WeakPolarHBondContact O-CB 3.45Å; D373-A377 PolarHBondContact O-N 3.19Å
374V98.6Very high97.4Very high0 Ų064.8 Ų64.80%032%0.32CS..Hα-helixtrans-66.1-42.7177.4-1770000111.2F96 I100 I103 L156 Y370 R371 R376 A377 L378F96-V374 HydrophobicContact CE2-CG2 4.07Å; I100-V374 HydrophobicContact CB-CG2 4.46Å; I100-V374 HydrophobicContact CG1-CG2 3.67Å; I103-V374 HydrophobicContact CB-CB 4.37Å; I103-V374 HydrophobicContact CB-CG1 3.69Å; I103-V374 HydrophobicContact CG1-CB 4.29Å; I103-V374 HydrophobicContact CG1-CG1 4.17Å; I103-V374 HydrophobicContact CG2-CB 4.44Å; I103-V374 HydrophobicContact CG2-CG1 3.68Å; L156-V374 HydrophobicContact CD1-CG2 4.05Å; L156-V374 HydrophobicContact CD2-CG2 4.14Å; Y370-V374 VanDerWaalsContact O-CG2 3.31Å; Y370-V374 WeakPolarHBondContact O-CG2 3.16Å; Y370-V374 PolarHBondContact O-N 2.93Å; R371-V374 PolarHBondContact O-N 3.29Å; V374-R376 VanDerWaalsContact C-N 3.31Å; V374-R376 PolarHBondContact O-N 3.26Å; V374-A377 PolarHBondContact O-N 2.91Å; V374-L378 WeakPolarHBondContact O-CB 3.46Å; V374-L378 PolarHBondContact O-N 3.25Å
375I98.5Very high97.1Very high82 Ų8264.3 Ų64.342%0.42131%0.307SS..Hα-helixtrans-60.7-42.7175.1-69.2165.7000110.8I103 R371 L378 T379I103-I375 HydrophobicContact CD1-CD1 4.02Å; I103-I375 HydrophobicContact CD1-CG1 3.85Å; I103-I375 HydrophobicContact CG1-CG1 4.31Å; I103-I375 HydrophobicContact CG2-CG1 4.2Å; R371-I375 VanDerWaalsContact O-CG1 3.27Å; R371-I375 WeakPolarHBondContact O-CG1 3.41Å; R371-I375 PolarHBondContact O-N 3.29Å; I375-L378 PolarHBondContact O-N 2.77Å; I375-T379 WeakPolarHBondContact O-CB 3.38Å; I375-T379 PolarHBondContact O-N 2.79Å; I375-T379 PolarHBondContact O-OG1 2.84Å
376R98.5Very high96.9Very high142 Ų14261.1 Ų61.154%0.53629%0.293SS..Hα-helixtrans-61.9-47.1176.1-175.4174.968.6-120.4-3.1111S372 D373 V374 L378 T379 I380S372-R376 WeakPolarHBondContact O-CB 3.43Å; S372-R376 PolarHBondContact O-N 2.64Å; D373-R376 PolarHBondContact O-N 3.05Å; D373-R376 IonicContact OD1-CZ 3.58Å; D373-R376 IonicContact OD1-NH1 2.67Å; D373-R376 PolarHBondContact OD1-NH1 3.41Å; D373-R376 IonicContact OD1-NH2 2.93Å; D373-R376 PolarHBondContact OD1-NH2 2.99Å; V374-R376 VanDerWaalsContact C-N 3.31Å; V374-R376 PolarHBondContact O-N 3.26Å; R376-L378 PolarHBondContact O-N 2.66Å; R376-T379 PolarHBondContact O-N 3.24Å; R376-I380 HydrophobicContact CG-CD1 4Å; R376-I380 WeakPolarHBondContact O-CG1 3.45Å; R376-I380 PolarHBondContact O-N 3.28Å
377A98.5Very high96.5Very high5 Ų560.2 Ų60.24%0.04129%0.289CS..Hα-helixtrans-61-42.3178.700000112.4L156 Q157 V160 D373 V374 I380 A381L156-A377 HydrophobicContact CD2-CB 3.99Å; L156-A377 HydrophobicContact CG-CB 3.87Å; Q157-A377 PolarHBondContact NE2-O 2.87Å; Q157-A377 VanDerWaalsContact NE2-O 3.12Å; Q157-A377 PolarHBondContact OE1-O 3.34Å; V160-A377 HydrophobicContact CB-CB 4.47Å; V160-A377 HydrophobicContact CG2-CB 4.05Å; D373-A377 WeakPolarHBondContact O-CB 3.45Å; D373-A377 PolarHBondContact O-N 3.19Å; V374-A377 PolarHBondContact O-N 2.91Å; A377-I380 PolarHBondContact O-N 2.96Å; A377-A381 VanDerWaalsContact O-CB 3.3Å; A377-A381 WeakPolarHBondContact O-CB 3.32Å; A377-A381 PolarHBondContact O-N 3.45Å
378L98.3Very high96Very high4 Ų460 Ų602%0.02129%0.285CS..Hα-helixtrans-63.5-45.9174.7-177.462.2000112.2I103 L104 A107 V160 V164 V374 I375 R376 I380 A381 E382I103-L378 HydrophobicContact CG2-CD2 4.22Å; L104-L378 HydrophobicContact CD2-CD1 4.32Å; A107-L378 HydrophobicContact CB-CD2 3.72Å; V160-L378 HydrophobicContact CG1-CB 4.15Å; V160-L378 HydrophobicContact CG1-CD1 3.86Å; V164-L378 HydrophobicContact CG2-CD1 4.07Å; V374-L378 WeakPolarHBondContact O-CB 3.46Å; V374-L378 PolarHBondContact O-N 3.25Å; I375-L378 PolarHBondContact O-N 2.77Å; R376-L378 PolarHBondContact O-N 2.66Å; L378-I380 VanDerWaalsContact C-N 3.27Å; L378-I380 PolarHBondContact O-N 2.69Å; L378-A381 PolarHBondContact O-N 2.96Å; L378-A381 VanDerWaalsContact O-N 3.17Å; L378-E382 HydrophobicContact CD1-CG 4.07Å; L378-E382 HydrophobicContact CG-CG 4.42Å; L378-E382 WeakPolarHBondContact O-CB 3.44Å; L378-E382 VanDerWaalsContact O-CG 3.29Å; L378-E382 WeakPolarHBondContact O-CG 3.38Å; L378-E382 PolarHBondContact O-N 3.17Å
379T97.9Very high95.5Very high54 Ų5455.8 Ų55.833%0.33127%0.266SS..Hα-helixtrans-60.7-38.1177.5-570000111.9I375 R376 K383I375-T379 WeakPolarHBondContact O-CB 3.38Å; I375-T379 PolarHBondContact O-N 2.79Å; I375-T379 PolarHBondContact O-OG1 2.84Å; R376-T379 PolarHBondContact O-N 3.24Å; T379-K383 WeakPolarHBondContact O-CG 3.32Å
380I96.9Very high95Very high76 Ų7653 Ų5339%0.3925%0.251SS..Hα-helixtrans-67.8-48.8174.6-70166.8000110.1R376 A377 L378 E382 K383 K384R376-I380 HydrophobicContact CG-CD1 4Å; R376-I380 WeakPolarHBondContact O-CG1 3.45Å; R376-I380 PolarHBondContact O-N 3.28Å; A377-I380 PolarHBondContact O-N 2.96Å; L378-I380 VanDerWaalsContact C-N 3.27Å; L378-I380 PolarHBondContact O-N 2.69Å; I380-E382 VanDerWaalsContact C-N 3.32Å; I380-E382 PolarHBondContact O-N 2.8Å; I380-K383 PolarHBondContact O-N 3.34Å; I380-K384 PolarHBondContact O-N 2.94Å
381A97.3Very high94.6Very high0 Ų051.7 Ų51.70%025%0.249CC..Hα-helixtrans-61.6-36.7-176.500000113.2V160 D161 V164 N166 A377 L378 K383 K384V160-A381 HydrophobicContact CB-CB 4.46Å; V160-A381 HydrophobicContact CG1-CB 3.73Å; D161-A381 WeakPolarHBondContact OD1-CB 3.34Å; V164-A381 HydrophobicContact CB-CB 4.35Å; V164-A381 HydrophobicContact CG2-CB 3.87Å; N166-A381 WeakPolarHBondContact ND2-CA 3.46Å; N166-A381 WeakPolarHBondContact ND2-CB 3.47Å; N166-A381 PolarHBondContact ND2-O 3.19Å; A377-A381 VanDerWaalsContact O-CB 3.3Å; A377-A381 WeakPolarHBondContact O-CB 3.32Å; A377-A381 PolarHBondContact O-N 3.45Å; L378-A381 PolarHBondContact O-N 2.96Å; L378-A381 VanDerWaalsContact O-N 3.17Å; A381-K383 VanDerWaalsContact C-N 3.35Å; A381-K384 PolarHBondContact O-N 3.46Å
382E95.1Very high94.4Very high68 Ų6853 Ų5332%0.31826%0.26SS..Hα-helixtrans-74.1-23.7-180-73174.6161.300114.2R112 V164 L378 I380 K384R112-E382 WeakPolarHBondContact CB-OE1 3.48Å; R112-E382 IonicContact CZ-OE1 3.18Å; R112-E382 IonicContact CZ-OE2 2.64Å; R112-E382 IonicContact NE-OE1 3.77Å; R112-E382 PolarHBondContact NE-OE1 3.14Å; R112-E382 IonicContact NE-OE2 3.15Å; R112-E382 IonicContact NH2-OE1 2.87Å; R112-E382 PolarHBondContact NH2-OE1 3.44Å; R112-E382 IonicContact NH2-OE2 2.74Å; R112-E382 PolarHBondContact NH2-OE2 2.93Å; V164-E382 HydrophobicContact CG2-CG 4.44Å; L378-E382 HydrophobicContact CD1-CG 4.07Å; L378-E382 HydrophobicContact CG-CG 4.42Å; L378-E382 WeakPolarHBondContact O-CB 3.44Å; L378-E382 VanDerWaalsContact O-CG 3.29Å; L378-E382 WeakPolarHBondContact O-CG 3.38Å; L378-E382 PolarHBondContact O-N 3.17Å; I380-E382 VanDerWaalsContact C-N 3.32Å; I380-E382 PolarHBondContact O-N 2.8Å; E382-K384 VanDerWaalsContact C-N 3.33Å
383K93.5Very high94.2Very high172 Ų17251.2 Ų51.275%0.74824%0.244SC*.Hα-helixtrans-79.6-19.1175.1-71.3175.2-177.2-179.60112.5T379 I380 A381T379-K383 WeakPolarHBondContact O-CG 3.32Å; I380-K383 PolarHBondContact O-N 3.34Å; A381-K383 VanDerWaalsContact C-N 3.35Å
384K91.8Very high93.9Very high41 Ų4151 Ų5118%0.17825%0.245CC..SBendtrans-73.3150.4177-64.6177.2-170.4176.80110.4D161 N166 D168 I380 A381 E382D161-K384 IonicContact OD1-NZ 2.74Å; D161-K384 PolarHBondContact OD1-NZ 3.18Å; D161-K384 IonicContact OD2-NZ 3.58Å; D161-K384 PolarHBondContact OD2-NZ 3.02Å; N166-K384 HydrophobicContact CB-CB 3.88Å; D168-K384 HydrophobicContact CB-CD 4.28Å; D168-K384 WeakPolarHBondContact OD2-CD 3.32Å; D168-K384 WeakPolarHBondContact OD2-CE 3.26Å; D168-K384 IonicContact OD2-NZ 3.19Å; D168-K384 PolarHBondContact OD2-NZ 3.13Å; I380-K384 PolarHBondContact O-N 2.94Å; A381-K384 PolarHBondContact O-N 3.46Å; E382-K384 VanDerWaalsContact C-N 3.33Å
385K90.6Very high93.7Very high72 Ų7257.4 Ų57.431%0.31328%0.275SS..PPolyproline II helixtrans-75.2165.1174-66.5-165.3174.7-143.50110.4N166 E167 E426 S427 F428N166-K385 CarbonylContact C-O 3.5Å; N166-K385 WeakPolarHBondContact CA-O 3.46Å; N166-K385 WeakPolarHBondContact CB-O 3.35Å; E167-K385 WeakPolarHBondContact CB-O 3.45Å; E167-K385 PolarHBondContact N-O 2.79Å; E167-K385 PolarHBondContact OE1-N 2.58Å; K385-E426 PolarHBondContact NZ-O 3.15Å; K385-S427 CarbonylContact C-O 3.5Å; K385-S427 WeakPolarHBondContact CA-O 3.46Å; K385-S427 WeakPolarHBondContact CB-O 3.3Å; K385-F428 WeakPolarHBondContact CD-O 3.32Å
386K92.6Very high93.6Very high70 Ų7057.6 Ų57.630%0.30428%0.28SS..BIsolated β-bridgetrans-69.7158.2166.8-55.1-57.4-179.5-170.80110.1V164 G165 S427 F428 S429V164-K386 PolarHBondContact O-NZ 3.31Å; G165-K386 WeakPolarHBondContact O-CD 3.48Å; K386-S427 PolarHBondContact N-O 3.39Å; K386-F428 HydrophobicContact CB-CD1 3.99Å; K386-F428 HydrophobicContact CB-CE1 4.18Å; K386-F428 HydrophobicContact CB-CG 4.29Å; K386-S429 VanDerWaalsContact O-CB 3.25Å; K386-S429 WeakPolarHBondContact O-CB 3.18Å; K386-S429 PolarHBondContact O-N 3.32Å; K386-S429 PolarHBondContact O-OG 3.36Å
387P89.8Confident93.5Very high7 Ų758.1 Ų58.15%0.04528%0.283CS..PPolyproline II helixtrans-53.5160.2172.4-24.434.6000111.5G165 N166 L172 I389 F428 S429G165-P387 VanDerWaalsContact O-CD 3.31Å; G165-P387 WeakPolarHBondContact O-CD 3.5Å; N166-P387 WeakPolarHBondContact O-CG 3.45Å; L172-P387 VanDerWaalsContact C-CG 3.48Å; L172-P387 WeakPolarHBondContact O-CG 3.39Å; P387-I389 PolarHBondContact O-N 3.29Å; P387-F428 WeakPolarHBondContact O-CD1 3.41Å; P387-S429 VanDerWaalsContact C-OG 3.26Å
388P86.7Confident93.2Very high24 Ų2465.5 Ų65.516%0.15632%0.321CS..PPolyproline II helixtrans-58.2137.9178.6-25.136.2000110.8D390 S391 S429P388-D390 VanDerWaalsContact CB-OD1 3.23Å; P388-D390 WeakPolarHBondContact CB-OD1 3.39Å; P388-D390 PolarHBondContact O-N 3.01Å; P388-D390 VanDerWaalsContact O-N 3.14Å; P388-S391 WeakPolarHBondContact O-CB 3.26Å; P388-S391 PolarHBondContact O-N 2.89Å; P388-S391 PolarHBondContact O-OG 2.66Å; P388-S429 WeakPolarHBondContact CA-O 3.4Å; P388-S429 WeakPolarHBondContact CD-OG 3.45Å; P388-S429 WeakPolarHBondContact CG-OG 3.43Å; P388-S429 VanDerWaalsContact N-OG 3.12Å
389I87.9Confident92.8Very high41 Ų4170.5 Ų70.521%0.2135%0.352CS..G310 helixtrans-57.7-34.4-174.9-166.5174000112.4P387 S391 M392 L411 L412 F428P387-I389 PolarHBondContact O-N 3.29Å; I389-S391 PolarHBondContact O-N 2.93Å; I389-M392 VanDerWaalsContact O-CG 3.23Å; I389-M392 WeakPolarHBondContact O-CG 3.2Å; I389-M392 PolarHBondContact O-N 2.94Å; I389-L411 HydrophobicContact CD1-CD2 4.15Å; I389-L411 HydrophobicContact CG1-CD2 4.06Å; I389-L412 HydrophobicContact CG2-CD2 4.05Å; I389-F428 HydrophobicContact CB-CD1 3.88Å; I389-F428 HydrophobicContact CB-CE1 4.3Å; I389-F428 HydrophobicContact CB-CG 4.33Å; I389-F428 HydrophobicContact CG1-CD1 4.37Å; I389-F428 HydrophobicContact CG1-CE1 4.3Å
390D87.5Confident92.5Very high16 Ų1669.8 Ų69.89%0.08635%0.346CS..G310 helixtrans-75.2-11.1179.668.6-31.1000113.8P388 M392 F393 K408 L412P388-D390 VanDerWaalsContact CB-OD1 3.23Å; P388-D390 WeakPolarHBondContact CB-OD1 3.39Å; P388-D390 PolarHBondContact O-N 3.01Å; P388-D390 VanDerWaalsContact O-N 3.14Å; D390-M392 PolarHBondContact O-N 2.79Å; D390-F393 PolarHBondContact O-N 2.79Å; D390-K408 HydrophobicContact CB-CD 4.13Å; D390-K408 HydrophobicContact CB-CG 4.1Å; D390-K408 WeakPolarHBondContact OD2-CE 3.3Å; D390-K408 IonicContact OD2-NZ 3.95Å; D390-K408 PolarHBondContact OD2-NZ 3Å; D390-L412 HydrophobicContact CB-CD1 4.02Å; D390-L412 HydrophobicContact CB-CD2 4.24Å; D390-L412 HydrophobicContact CB-CG 4.4Å
391S91Very high92.3Very high17 Ų1768.4 Ų68.412%0.11934%0.341CS..G310 helixtrans-61-22.6169.673.90000111.3R174 P388 I389 F393 T394R174-S391 PolarHBondContact NH2-O 3.29Å; P388-S391 WeakPolarHBondContact O-CB 3.26Å; P388-S391 PolarHBondContact O-N 2.89Å; P388-S391 PolarHBondContact O-OG 2.66Å; I389-S391 PolarHBondContact O-N 2.93Å; S391-F393 PolarHBondContact O-N 3.48Å; S391-T394 PolarHBondContact O-N 3.27Å; S391-T394 PolarHBondContact O-OG1 3.35Å
392M93.9Very high92.3Very high112 Ų11273.4 Ų73.455%0.55237%0.373SS*.G310 helixtrans-57.5-19.9176.776.3-176.6-6000114.2I389 D390 L411I389-M392 VanDerWaalsContact O-CG 3.23Å; I389-M392 WeakPolarHBondContact O-CG 3.2Å; I389-M392 PolarHBondContact O-N 2.94Å; D390-M392 PolarHBondContact O-N 2.79Å; M392-L411 HydrophobicContact SD-CD2 3.6Å
393F95Very high92.3Very high23 Ų2379.1 Ų79.110%0.10139%0.392CS..G310 helixtrans-94.7-16.1179.4-60.5-81000113.9D390 S391 L400 L404 Q407 K408 L411D390-F393 PolarHBondContact O-N 2.79Å; S391-F393 PolarHBondContact O-N 3.48Å; F393-L400 HydrophobicContact CB-CD1 4.13Å; F393-L400 WeakPolarHBondContact O-CD1 3.09Å; F393-L404 HydrophobicContact CD1-CD2 4.31Å; F393-Q407 HydrophobicContact CD1-CB 4.37Å; F393-Q407 HydrophobicContact CE1-CB 3.75Å; F393-Q407 HydrophobicContact CZ-CB 4.39Å; F393-K408 HydrophobicContact CB-CB 4.35Å; F393-K408 HydrophobicContact CD1-CB 4.47Å; F393-K408 HydrophobicContact CD2-CB 3.67Å; F393-K408 HydrophobicContact CD2-CG 4.04Å; F393-K408 HydrophobicContact CE2-CB 4.03Å; F393-K408 HydrophobicContact CE2-CG 4.5Å; F393-K408 HydrophobicContact CG-CB 3.91Å; F393-L411 HydrophobicContact CE2-CB 4.17Å; F393-L411 HydrophobicContact CE2-CD2 3.58Å; F393-L411 HydrophobicContact CZ-CB 4.17Å; F393-L411 HydrophobicContact CZ-CD2 4Å
394T92Very high92.4Very high45 Ų4572 Ų7228%0.27636%0.362SS..THydrogen-bonded Turntrans-83.4155-177.470.60000111.3R174 S391 V396R174-T394 VanDerWaalsContact CZ-O 3.32Å; R174-T394 PolarHBondContact NH1-O 2.79Å; R174-T394 PolarHBondContact NH2-O 3.35Å; R174-T394 PolarHBondContact NH2-OG1 2.89Å; S391-T394 PolarHBondContact O-N 3.27Å; S391-T394 PolarHBondContact O-OG1 3.35Å; T394-V396 PolarHBondContact O-N 3.33Å; T394-V396 VanDerWaalsContact O-N 3.14Å
395H93.6Very high92.4Very high135 Ų13575 Ų7563%0.62538%0.376SS*.THydrogen-bonded Turntrans63.79.4179.7-48.3-62.8000116R174 Y397R174-H395 PolarHBondContact NH1-CD2 2.96Å; H395-Y397 VanDerWaalsContact C-N 3.27Å; H395-Y397 CarbonylContact C-O 3.6Å; H395-Y397 WeakPolarHBondContact CA-O 3.3Å
396V96.5Very high92.6Very high86 Ų8677.9 Ų77.952%0.52139%0.389SS..SBendtrans-62.9-41.9163179.20000109.8T394 L404T394-V396 PolarHBondContact O-N 3.33Å; T394-V396 VanDerWaalsContact O-N 3.14Å; V396-L404 HydrophobicContact CB-CD1 4.01Å; V396-L404 HydrophobicContact CG1-CD1 4.1Å
397Y96.2Very high92.7Very high153 Ų15377.8 Ų77.860%0.639%0.39SS*.SBendtrans-126.8168.9164.7-67.9-87.9000108H395 V399 T401 L404H395-Y397 VanDerWaalsContact C-N 3.27Å; H395-Y397 CarbonylContact C-O 3.6Å; H395-Y397 WeakPolarHBondContact CA-O 3.3Å; Y397-V399 VanDerWaalsContact C-N 3.31Å; Y397-V399 WeakPolarHBondContact CB-O 3.39Å; Y397-V399 PolarHBondContact O-N 3.47Å; Y397-T401 HydrophobicContact CD2-CG2 3.94Å; Y397-T401 HydrophobicContact CE2-CG2 4.3Å; Y397-T401 HydrophobicContact CG-CG2 4.4Å; Y397-L404 HydrophobicContact CD2-CD1 4.08Å
398D93Very high92.7Very high159 Ų15980 Ų8085%0.8540%0.399SS*.SBendtrans-59.8-43.1175.1-172.639000111.6
399V91Very high92.7Very high109 Ų10981.6 Ų81.666%0.66141%0.411SS*.SBendtrans-114.9138173.6-176.50000110Y397 T401Y397-V399 VanDerWaalsContact C-N 3.31Å; Y397-V399 WeakPolarHBondContact CB-O 3.39Å; Y397-V399 PolarHBondContact O-N 3.47Å; V399-T401 PolarHBondContact O-N 3.21Å
400L89.7Confident92.8Very high40 Ų4084.7 Ų84.721%0.20942%0.424CS..  trans-63.9126178.6-160.963.8000110F393 L404 E405 K408F393-L400 HydrophobicContact CB-CD1 4.13Å; F393-L400 WeakPolarHBondContact O-CD1 3.09Å; L400-L404 HydrophobicContact CD1-CB 3.47Å; L400-L404 VanDerWaalsContact CD1-CB 3.47Å; L400-L404 HydrophobicContact CD1-CD1 4Å; L400-L404 HydrophobicContact CD1-CG 4.36Å; L400-L404 HydrophobicContact CG-CB 3.91Å; L400-E405 HydrophobicContact CB-CG 4.18Å; L400-E405 HydrophobicContact CD2-CB 4.33Å; L400-E405 HydrophobicContact CD2-CG 3.44Å; L400-E405 VanDerWaalsContact CD2-CG 3.44Å; L400-E405 HydrophobicContact CG-CG 3.74Å; L400-K408 HydrophobicContact CD2-CD 4.2Å
401T94.7Very high92.8Very high46 Ų4685.8 Ų85.828%0.28243%0.43SS..  trans-75.5153.7178.4670000110.4Y397 V399 R403 L404 E405Y397-T401 HydrophobicContact CD2-CG2 3.94Å; Y397-T401 HydrophobicContact CE2-CG2 4.3Å; Y397-T401 HydrophobicContact CG-CG2 4.4Å; V399-T401 PolarHBondContact O-N 3.21Å; T401-R403 PolarHBondContact O-N 3.46Å; T401-L404 PolarHBondContact O-N 2.99Å; T401-L404 WeakPolarHBondContact OG1-CG 3.35Å; T401-L404 PolarHBondContact OG1-N 3.08Å; T401-E405 PolarHBondContact O-N 3.38Å
402P95.5Very high92.4Very high106 Ų10686.7 Ų86.769%0.68843%0.433SS*.Hα-helixtrans-54.7-31.7177.5-28.435.3000113.6K406P402-K406 WeakPolarHBondContact O-CB 3.17Å; P402-K406 PolarHBondContact O-N 3.03Å
403R96.8Very high91.7Very high188 Ų18882.4 Ų82.471%0.70942%0.416SS*.Hα-helixtrans-68-43175-175177.5178.1177.10.4112T401 K406 Q407T401-R403 PolarHBondContact O-N 3.46Å; R403-K406 PolarHBondContact O-N 3.42Å; R403-Q407 WeakPolarHBondContact O-CG 3.45Å; R403-Q407 PolarHBondContact O-N 3.38Å
404L95.5Very high91.1Very high22 Ų2284.6 Ų84.612%0.11543%0.426CS..Hα-helixtrans-70-36.3176.8-70.4171.1000111.5F393 V396 Y397 L400 T401 K406 Q407 K408F393-L404 HydrophobicContact CD1-CD2 4.31Å; V396-L404 HydrophobicContact CB-CD1 4.01Å; V396-L404 HydrophobicContact CG1-CD1 4.1Å; Y397-L404 HydrophobicContact CD2-CD1 4.08Å; L400-L404 HydrophobicContact CD1-CB 3.47Å; L400-L404 VanDerWaalsContact CD1-CB 3.47Å; L400-L404 HydrophobicContact CD1-CD1 4Å; L400-L404 HydrophobicContact CD1-CG 4.36Å; L400-L404 HydrophobicContact CG-CB 3.91Å; T401-L404 PolarHBondContact O-N 2.99Å; T401-L404 WeakPolarHBondContact OG1-CG 3.35Å; T401-L404 PolarHBondContact OG1-N 3.08Å; L404-K406 VanDerWaalsContact C-N 3.33Å; L404-K406 PolarHBondContact O-N 2.54Å; L404-Q407 PolarHBondContact O-N 3.15Å; L404-K408 VanDerWaalsContact O-CB 3.3Å; L404-K408 WeakPolarHBondContact O-CB 3.27Å; L404-K408 PolarHBondContact O-N 3.03Å
405E91.3Very high90.4Very high103 Ų10383.2 Ų83.248%0.48142%0.418SS..Hα-helixtrans-58.9-43.9171.2-78.9-178.5177.200112.2L400 T401 K408 S409L400-E405 HydrophobicContact CB-CG 4.18Å; L400-E405 HydrophobicContact CD2-CB 4.33Å; L400-E405 HydrophobicContact CD2-CG 3.44Å; L400-E405 VanDerWaalsContact CD2-CG 3.44Å; L400-E405 HydrophobicContact CG-CG 3.74Å; T401-E405 PolarHBondContact O-N 3.38Å; E405-K408 PolarHBondContact O-N 2.88Å; E405-S409 WeakPolarHBondContact O-CB 3.05Å; E405-S409 PolarHBondContact O-N 3.2Å; E405-S409 PolarHBondContact O-OG 2.9Å
406K93.7Very high89.3Confident133 Ų13379.8 Ų79.858%0.57841%0.409SS*.Hα-helixtrans-60.8-49.9174.6-179178.7171.71800111.4P402 R403 L404 K408 S409 E410P402-K406 WeakPolarHBondContact O-CB 3.17Å; P402-K406 PolarHBondContact O-N 3.03Å; R403-K406 PolarHBondContact O-N 3.42Å; L404-K406 VanDerWaalsContact C-N 3.33Å; L404-K406 PolarHBondContact O-N 2.54Å; K406-K408 PolarHBondContact O-N 2.88Å; K406-S409 WeakPolarHBondContact O-CB 3.46Å; K406-S409 PolarHBondContact O-N 3.46Å; K406-S409 VanDerWaalsContact O-N 3.14Å; K406-E410 WeakPolarHBondContact CE-OE1 3.07Å; K406-E410 IonicContact NZ-OE1 3.65Å; K406-E410 WeakPolarHBondContact O-CG 3.42Å; K406-E410 PolarHBondContact O-N 3.12Å
407Q95.7Very high88Confident69 Ų6983.9 Ų83.932%0.32242%0.42SS..Hα-helixtrans-61.1-42.6178.8-72.1174.7-1.100112.4F393 R403 L404 S409 E410 L411F393-Q407 HydrophobicContact CD1-CB 4.37Å; F393-Q407 HydrophobicContact CE1-CB 3.75Å; F393-Q407 HydrophobicContact CZ-CB 4.39Å; R403-Q407 WeakPolarHBondContact O-CG 3.45Å; R403-Q407 PolarHBondContact O-N 3.38Å; L404-Q407 PolarHBondContact O-N 3.15Å; Q407-S409 VanDerWaalsContact C-N 3.32Å; Q407-S409 PolarHBondContact O-N 3Å; Q407-E410 PolarHBondContact O-N 3.46Å; Q407-L411 PolarHBondContact O-N 2.79Å
408K90Very high86.6Confident52 Ų5280.8 Ų80.823%0.22641%0.412CS..Hα-helixtrans-56.4-46.8172.7171.4175.5168.6158.50111.4D390 F393 L400 L404 E405 K406 L411 L412D390-K408 HydrophobicContact CB-CD 4.13Å; D390-K408 HydrophobicContact CB-CG 4.1Å; D390-K408 WeakPolarHBondContact OD2-CE 3.3Å; D390-K408 IonicContact OD2-NZ 3.95Å; D390-K408 PolarHBondContact OD2-NZ 3Å; F393-K408 HydrophobicContact CB-CB 4.35Å; F393-K408 HydrophobicContact CD1-CB 4.47Å; F393-K408 HydrophobicContact CD2-CB 3.67Å; F393-K408 HydrophobicContact CD2-CG 4.04Å; F393-K408 HydrophobicContact CE2-CB 4.03Å; F393-K408 HydrophobicContact CE2-CG 4.5Å; F393-K408 HydrophobicContact CG-CB 3.91Å; L400-K408 HydrophobicContact CD2-CD 4.2Å; L404-K408 VanDerWaalsContact O-CB 3.3Å; L404-K408 WeakPolarHBondContact O-CB 3.27Å; L404-K408 PolarHBondContact O-N 3.03Å; E405-K408 PolarHBondContact O-N 2.88Å; K406-K408 PolarHBondContact O-N 2.88Å; K408-L411 PolarHBondContact O-N 3.21Å; K408-L412 HydrophobicContact CG-CD1 3.99Å; K408-L412 WeakPolarHBondContact O-CG 3.3Å; K408-L412 PolarHBondContact O-N 3.02Å
409S86.1Confident84.9Confident59 Ų5976.4 Ų76.441%0.41339%0.394SS..Hα-helixtrans-65.2-40.5179.2-58.80000112.1E405 K406 Q407 L412 A413E405-S409 WeakPolarHBondContact O-CB 3.05Å; E405-S409 PolarHBondContact O-N 3.2Å; E405-S409 PolarHBondContact O-OG 2.9Å; K406-S409 WeakPolarHBondContact O-CB 3.46Å; K406-S409 PolarHBondContact O-N 3.46Å; K406-S409 VanDerWaalsContact O-N 3.14Å; Q407-S409 VanDerWaalsContact C-N 3.32Å; Q407-S409 PolarHBondContact O-N 3Å; S409-L412 PolarHBondContact O-N 2.77Å; S409-A413 WeakPolarHBondContact O-CB 3.45Å; S409-A413 PolarHBondContact O-N 2.68Å
410E89.7Confident83.4Confident106 Ų10674.5 Ų74.550%0.49539%0.39SS..Hα-helixtrans-61.6-44.9175-74171.9171.400111.7K406 Q407 A413 H414K406-E410 WeakPolarHBondContact CE-OE1 3.07Å; K406-E410 IonicContact NZ-OE1 3.65Å; K406-E410 WeakPolarHBondContact O-CG 3.42Å; K406-E410 PolarHBondContact O-N 3.12Å; Q407-E410 PolarHBondContact O-N 3.46Å; E410-A413 PolarHBondContact O-N 2.72Å; E410-H414 WeakPolarHBondContact O-CB 3.47Å; E410-H414 PolarHBondContact O-N 2.92Å
411L88.3Confident82.3Confident38 Ų3878.8 Ų78.820%0.19942%0.418CS..Hα-helixtrans-61.2-49.5175.8179.167.4000111.5I389 M392 F393 Q407 K408 A413 H414 C415I389-L411 HydrophobicContact CD1-CD2 4.15Å; I389-L411 HydrophobicContact CG1-CD2 4.06Å; M392-L411 HydrophobicContact SD-CD2 3.6Å; F393-L411 HydrophobicContact CE2-CB 4.17Å; F393-L411 HydrophobicContact CE2-CD2 3.58Å; F393-L411 HydrophobicContact CZ-CB 4.17Å; F393-L411 HydrophobicContact CZ-CD2 4Å; Q407-L411 PolarHBondContact O-N 2.79Å; K408-L411 PolarHBondContact O-N 3.21Å; L411-A413 VanDerWaalsContact C-N 3.28Å; L411-A413 PolarHBondContact O-N 2.71Å; L411-H414 WeakPolarHBondContact O-CA 3.41Å; L411-H414 WeakPolarHBondContact O-CB 3.41Å; L411-H414 PolarHBondContact O-N 2.88Å; L411-H414 VanDerWaalsContact O-N 3.07Å; L411-C415 PolarHBondContact O-N 3.39Å; L411-C415 PolarHBondContact O-SG 2.86Å
412L81.5Confident81.7Confident37 Ų3779.2 Ų79.219%0.19443%0.426CS..Hα-helixtrans-64.2-36-178.6-69.7171.8000111.6I389 D390 K408 S409 S416 P556I389-L412 HydrophobicContact CG2-CD2 4.05Å; D390-L412 HydrophobicContact CB-CD1 4.02Å; D390-L412 HydrophobicContact CB-CD2 4.24Å; D390-L412 HydrophobicContact CB-CG 4.4Å; K408-L412 HydrophobicContact CG-CD1 3.99Å; K408-L412 WeakPolarHBondContact O-CG 3.3Å; K408-L412 PolarHBondContact O-N 3.02Å; S409-L412 PolarHBondContact O-N 2.77Å; L412-S416 WeakPolarHBondContact O-CB 3.14Å; L412-S416 PolarHBondContact O-N 2.76Å; L412-P556 HydrophobicContact CB-CB 3.76Å; L412-P556 HydrophobicContact CB-CG 3.57Å; L412-P556 HydrophobicContact CD1-CG 3.57Å; L412-P556 HydrophobicContact CG-CG 4.18Å
413A79.9Confident80.9Confident22 Ų2278.5 Ų78.518%0.18241%0.41CS..Hα-helixtrans-65.3-41.2171.200000111.9S409 E410 L411 S416 K417S409-A413 WeakPolarHBondContact O-CB 3.45Å; S409-A413 PolarHBondContact O-N 2.68Å; E410-A413 PolarHBondContact O-N 2.72Å; L411-A413 VanDerWaalsContact C-N 3.28Å; L411-A413 PolarHBondContact O-N 2.71Å; A413-S416 PolarHBondContact O-N 2.87Å; A413-S416 PolarHBondContact O-OG 3.05Å; A413-K417 WeakPolarHBondContact O-CG 3.47Å; A413-K417 PolarHBondContact O-N 3.4Å
414H83.5Confident80.2Confident68 Ų6873.6 Ų73.632%0.31540%0.403SS..Hα-helixtrans-61.9-51.5176.2-178.381.6000112.2E410 L411 S416 K417 M418 Y423E410-H414 WeakPolarHBondContact O-CB 3.47Å; E410-H414 PolarHBondContact O-N 2.92Å; L411-H414 WeakPolarHBondContact O-CA 3.41Å; L411-H414 WeakPolarHBondContact O-CB 3.41Å; L411-H414 PolarHBondContact O-N 2.88Å; L411-H414 VanDerWaalsContact O-N 3.07Å; H414-S416 PolarHBondContact O-N 3.41Å; H414-K417 PolarHBondContact O-N 3.12Å; H414-M418 VanDerWaalsContact CE1-CE 3.44Å; H414-M418 WeakPolarHBondContact CE1-CE 3.4Å; H414-M418 WeakPolarHBondContact O-CG 3.23Å; H414-M418 PolarHBondContact O-N 2.78Å; H414-Y423 AromaticContact CD2-CE2 3.83Å; H414-Y423 AromaticContact CD2-CZ 3.89Å; H414-Y423 AromaticContact NE2-CE2 3.51Å; H414-Y423 AromaticContact NE2-CZ 3.53Å; H414-Y423 PolarHBondContact NE2-OH 2.75Å
415C76.3Confident79Confident16 Ų1675 Ų7511%0.10841%0.41CS..Hα-helixtrans-59.4-30.3177.5-67.80000112.8L411L411-C415 PolarHBondContact O-N 3.39Å; L411-C415 PolarHBondContact O-SG 2.86Å
416S69.5Low78.1Confident63 Ų6377.4 Ų77.444%0.44142%0.422SS..Hα-helixtrans-75.9-22.217778.50000114.6L412 A413 H414 S557L412-S416 WeakPolarHBondContact O-CB 3.14Å; L412-S416 PolarHBondContact O-N 2.76Å; A413-S416 PolarHBondContact O-N 2.87Å; A413-S416 PolarHBondContact O-OG 3.05Å; H414-S416 PolarHBondContact O-N 3.41Å; S416-S557 WeakPolarHBondContact OG-CB 3.34Å
417K71.1Confident77.5Confident172 Ų17273.9 Ų73.975%0.74841%0.414SS*.Hα-helixtrans-91.7-34.4-179.6-72.1176.6-177.8179.90112A413 H414A413-K417 WeakPolarHBondContact O-CG 3.47Å; A413-K417 PolarHBondContact O-N 3.4Å; H414-K417 PolarHBondContact O-N 3.12Å
418M66.4Low76.8Confident88 Ų8873.5 Ų73.543%0.43341%0.411SS..SBendtrans-75146.5-178.7-66.3-62.6165.100110.8H414 A422 Y423H414-M418 VanDerWaalsContact CE1-CE 3.44Å; H414-M418 WeakPolarHBondContact CE1-CE 3.4Å; H414-M418 WeakPolarHBondContact O-CG 3.23Å; H414-M418 PolarHBondContact O-N 2.78Å; M418-A422 HydrophobicContact CB-CB 4.24Å; M418-Y423 HydrophobicContact CB-CD2 4.2Å; M418-Y423 HydrophobicContact CB-CE2 4.18Å; M418-Y423 HydrophobicContact CG-CE2 4.13Å
419S56.6Low76.1Confident67 Ų6771.6 Ų71.647%0.46941%0.405SS..  trans-59.4150.4175.358.10000110.1T421 A422S419-T421 WeakPolarHBondContact CB-OG1 3.25Å; S419-T421 PolarHBondContact O-N 2.67Å; S419-T421 PolarHBondContact OG-OG1 3.17Å; S419-A422 PolarHBondContact O-N 3.18Å
420A60.6Low75.3Confident70 Ų7072.9 Ų72.958%0.57940%0.401SS*.THydrogen-bonded Turntrans-56.8-14.217300000113.2
421T66.6Low74.3Confident130 Ų13069.9 Ų69.980%0.79839%0.391SS*.THydrogen-bonded Turntrans-82.5-18.5176.755.90000114.5S419S419-T421 WeakPolarHBondContact CB-OG1 3.25Å; S419-T421 PolarHBondContact O-N 2.67Å; S419-T421 PolarHBondContact OG-OG1 3.17Å
422A80.3Confident73.4Confident55 Ų5571 Ų7146%0.45540%0.401SS..THydrogen-bonded Turntrans-82.9-26-177.900000113.1M418 S419M418-A422 HydrophobicContact CB-CB 4.24Å; S419-A422 PolarHBondContact O-N 3.18Å
423Y80.1Confident73.3Confident90 Ų9071.9 Ų71.935%0.35341%0.405SS..SBendtrans-137.6143.2-179.8-67.1-88000109.8H414 M418 N425H414-Y423 AromaticContact CD2-CE2 3.83Å; H414-Y423 AromaticContact CD2-CZ 3.89Å; H414-Y423 AromaticContact NE2-CE2 3.51Å; H414-Y423 AromaticContact NE2-CZ 3.53Å; H414-Y423 PolarHBondContact NE2-OH 2.75Å; M418-Y423 HydrophobicContact CB-CD2 4.2Å; M418-Y423 HydrophobicContact CB-CE2 4.18Å; M418-Y423 HydrophobicContact CG-CE2 4.13Å; Y423-N425 WeakPolarHBondContact CB-OD1 3.31Å; Y423-N425 PolarHBondContact O-N 3.24Å
424P81.5Confident73.2Confident86 Ų8679 Ų7956%0.55843%0.427SS*.  trans-76.352.2178.431.9-33.8000112E426 S427 F428P424-E426 PolarHBondContact O-N 3.05Å; P424-E426 VanDerWaalsContact O-N 3.16Å; P424-S427 VanDerWaalsContact O-CB 3.31Å; P424-S427 WeakPolarHBondContact O-CB 3.18Å; P424-S427 PolarHBondContact O-N 2.99Å; P424-S427 PolarHBondContact O-OG 3.4Å; P424-F428 HydrophobicContact CG-CE2 4.26Å; P424-F428 WeakPolarHBondContact O-CD2 3.37Å
425N70.3Confident73.2Confident51 Ų5176.6 Ų76.627%0.27342%0.417SS..G310 helixtrans-58.3-32.2-172.3-70-30.2000112.8Y423 S427 F428Y423-N425 WeakPolarHBondContact CB-OD1 3.31Å; Y423-N425 PolarHBondContact O-N 3.24Å; N425-S427 PolarHBondContact O-N 3.27Å; N425-F428 PolarHBondContact O-N 3.35Å; N425-F428 VanDerWaalsContact O-N 3.15Å
426E73.5Confident73.6Confident153 Ų15381.8 Ų81.872%0.71544%0.44SS*.G310 helixtrans-65.1-25.8-179.9-62.2-175.4178.300113K385 P424 F428K385-E426 PolarHBondContact NZ-O 3.15Å; P424-E426 PolarHBondContact O-N 3.05Å; P424-E426 VanDerWaalsContact O-N 3.16Å; E426-F428 VanDerWaalsContact C-N 3.29Å; E426-F428 PolarHBondContact O-N 3.1Å
427S79.2Confident74.5Confident60 Ų6080 Ų8042%0.4243%0.426SS..G310 helixtrans-73.3-18.3177.2-52.90000113K385 K386 P424 N425K385-S427 CarbonylContact C-O 3.5Å; K385-S427 WeakPolarHBondContact CA-O 3.46Å; K385-S427 WeakPolarHBondContact CB-O 3.3Å; K386-S427 PolarHBondContact N-O 3.39Å; P424-S427 VanDerWaalsContact O-CB 3.31Å; P424-S427 WeakPolarHBondContact O-CB 3.18Å; P424-S427 PolarHBondContact O-N 2.99Å; P424-S427 PolarHBondContact O-OG 3.4Å; N425-S427 PolarHBondContact O-N 3.27Å
428F81Confident75.4Confident61 Ų6173.9 Ų73.927%0.26840%0.403SS..BIsolated β-bridgetrans-92.4141.5-179.4-66.8-103.5000110.9K385 K386 P387 I389 P424 N425 E426K385-F428 WeakPolarHBondContact CD-O 3.32Å; K386-F428 HydrophobicContact CB-CD1 3.99Å; K386-F428 HydrophobicContact CB-CE1 4.18Å; K386-F428 HydrophobicContact CB-CG 4.29Å; P387-F428 WeakPolarHBondContact O-CD1 3.41Å; I389-F428 HydrophobicContact CB-CD1 3.88Å; I389-F428 HydrophobicContact CB-CE1 4.3Å; I389-F428 HydrophobicContact CB-CG 4.33Å; I389-F428 HydrophobicContact CG1-CD1 4.37Å; I389-F428 HydrophobicContact CG1-CE1 4.3Å; P424-F428 HydrophobicContact CG-CE2 4.26Å; P424-F428 WeakPolarHBondContact O-CD2 3.37Å; N425-F428 PolarHBondContact O-N 3.35Å; N425-F428 VanDerWaalsContact O-N 3.15Å; E426-F428 VanDerWaalsContact C-N 3.29Å; E426-F428 PolarHBondContact O-N 3.1Å
429S76.4Confident76.4Confident12 Ų1275 Ų758%0.08442%0.417CS..PPolyproline II helixtrans-70.6161.9170.456.80000110.5E167 K386 P387 P388E167-S429 WeakPolarHBondContact OE2-CB 3.39Å; K386-S429 VanDerWaalsContact O-CB 3.25Å; K386-S429 WeakPolarHBondContact O-CB 3.18Å; K386-S429 PolarHBondContact O-N 3.32Å; K386-S429 PolarHBondContact O-OG 3.36Å; P387-S429 VanDerWaalsContact C-OG 3.26Å; P388-S429 WeakPolarHBondContact CA-O 3.4Å; P388-S429 WeakPolarHBondContact CD-OG 3.45Å; P388-S429 WeakPolarHBondContact CG-OG 3.43Å; P388-S429 VanDerWaalsContact N-OG 3.12Å
430Y69.5Low78Confident85 Ų8576.8 Ų76.833%0.33343%0.426SS..PPolyproline II helixtrans-87.5154.3176.1-63.4-84.8000110C432 Q536Y430-C432 PolarHBondContact O-N 3.4Å; Y430-Q536 WeakPolarHBondContact CD1-O 3.38Å; Y430-Q536 HydrophobicContact CD2-CB 3.68Å; Y430-Q536 HydrophobicContact CD2-CG 3.7Å; Y430-Q536 HydrophobicContact CE1-CB 4.48Å; Y430-Q536 WeakPolarHBondContact CE1-O 3.34Å; Y430-Q536 HydrophobicContact CE2-CB 3.58Å; Y430-Q536 HydrophobicContact CE2-CG 4.15Å; Y430-Q536 HydrophobicContact CG-CB 4.16Å; Y430-Q536 HydrophobicContact CG-CG 3.92Å; Y430-Q536 VanDerWaalsContact CZ-O 3.3Å
431P68Low79.3Confident44 Ų4474.2 Ų74.229%0.28640%0.402SS..PPolyproline II helixtrans-51.3128.3174.1-25.634.1000111.2L539P431-L539 PolarHBondContact O-N 2.93Å
432C69.7Low80.1Confident60 Ų6070.4 Ų70.441%0.40538%0.379SS..EExtended strand (participates in β ladder)trans-95.9107.5172.7-170.20000108.9Y430 L539Y430-C432 PolarHBondContact O-N 3.4Å; C432-L539 CarbonylContact C-O 3.57Å; C432-L539 VanDerWaalsContact CA-O 3.3Å; C432-L539 WeakPolarHBondContact CA-O 3.39Å; C432-L539 HydrophobicContact CB-CB 4.44Å
433L78.5Confident80.2Confident56 Ų5675.2 Ų75.229%0.29339%0.393SS..EExtended strand (participates in β ladder)trans-85.7120.1178.7-60.1175.3000109.3I435 C538 L539 V540 E541 V551L433-I435 HydrophobicContact CB-CD1 4.19Å; L433-I435 HydrophobicContact CB-CG1 4.14Å; L433-C538 HydrophobicContact CD1-CB 4.13Å; L433-C538 HydrophobicContact CG-CB 4.4Å; L433-L539 PolarHBondContact N-O 3.17Å; L433-V540 HydrophobicContact CB-CG2 4.36Å; L433-V540 CarbonylContact O-C 3.53Å; L433-V540 VanDerWaalsContact O-CA 3.3Å; L433-V540 WeakPolarHBondContact O-CA 3.16Å; L433-E541 PolarHBondContact O-N 2.76Å; L433-V551 HydrophobicContact CD1-CG1 4.12Å
434R78.9Confident80.2Confident171 Ų17175.4 Ų75.465%0.64540%0.397SS*.EExtended strand (participates in β ladder)trans-91116169.9-67.6-178.4-178.4146.45.1108.9E541R434-E541 WeakPolarHBondContact CA-O 3.38Å; R434-E541 HydrophobicContact CG-CB 4.34Å; R434-E541 IonicContact NE-OE2 3.52Å; R434-E541 PolarHBondContact NE-OE2 2.8Å
435I83.8Confident80.3Confident18 Ų1871.8 Ų71.89%0.09237%0.373CS..EExtended strand (participates in β ladder)trans-117.7134.3-171.3-56.4-175.7000109.4L433 V540 E541 R543 M550 V551L433-I435 HydrophobicContact CB-CD1 4.19Å; L433-I435 HydrophobicContact CB-CG1 4.14Å; I435-V540 HydrophobicContact CB-CG1 4.29Å; I435-V540 HydrophobicContact CD1-CG1 3.48Å; I435-V540 VanDerWaalsContact CD1-CG1 3.48Å; I435-V540 HydrophobicContact CD1-CG2 4.35Å; I435-V540 HydrophobicContact CG1-CG1 3.84Å; I435-E541 PolarHBondContact N-O 3.37Å; I435-R543 PolarHBondContact O-N 2.9Å; I435-M550 VanDerWaalsContact CD1-O 3.26Å; I435-M550 WeakPolarHBondContact CD1-O 3.21Å; I435-V551 HydrophobicContact CD1-CB 4.11Å; I435-V551 HydrophobicContact CD1-CG1 4.22Å; I435-V551 HydrophobicContact CD1-CG2 3.81Å
436H83.9Confident80.8Confident126 Ų12672.6 Ų72.658%0.58338%0.38SS*.EExtended strand (participates in β ladder)trans-95.6136.5170.2-63.186.9000108.8
437C88.3Confident80.9Confident24 Ų2471.7 Ų71.716%0.16238%0.38CS..  trans-73.2150.6177.2-69.80000111.8I542 N546 W548C437-I542 WeakPolarHBondContact SG-CG2 3.45Å; C437-N546 WeakPolarHBondContact CB-O 3.42Å; C437-W548 VanDerWaalsContact CA-O 3.32Å; C437-W548 WeakPolarHBondContact CA-O 3.39Å
438T89.8Confident80.4Confident44 Ų4469.9 Ų69.927%0.2737%0.367SS..BIsolated β-bridgetrans-120143174.550.70000110T440 G547 W548 M550T438-T440 PolarHBondContact O-N 3.43Å; T438-T440 PolarHBondContact OG1-O 2.86Å; T438-G547 CarbonylContact O-C 3.52Å; T438-G547 WeakPolarHBondContact O-CA 3.47Å; T438-W548 PolarHBondContact N-O 3.45Å; T438-W548 PolarHBondContact O-N 2.87Å; T438-W548 PolarHBondContact OG1-O 3.07Å; T438-M550 HydrophobicContact CG2-CE 4.01Å
439P88.1Confident80.3Confident111 Ų11173.9 Ų73.972%0.72139%0.391SS*.SBendtrans-59.4-34-179.5-25.734.7000113.4
440T90.2Very high80.6Confident105 Ų10579.1 Ų79.164%0.64441%0.412SS*.SBendtrans-130.8149.9-178.5550000110.5T438T438-T440 PolarHBondContact O-N 3.43Å; T438-T440 PolarHBondContact OG1-O 2.86Å
441L88.4Confident81.5Confident16 Ų1677.7 Ų77.78%0.08441%0.407CS..  trans-63.8137.6168.6-70.7168.5000110T446 C507 W548 M550 F589L441-T446 HydrophobicContact CB-CG2 3.71Å; L441-T446 HydrophobicContact CD1-CG2 4.24Å; L441-C507 HydrophobicContact CD2-CB 3.83Å; L441-W548 HydrophobicContact CD1-CD2 4.05Å; L441-W548 HydrophobicContact CD1-CE3 4.26Å; L441-W548 HydrophobicContact CD1-CH2 4.22Å; L441-W548 HydrophobicContact CD1-CZ2 4.02Å; L441-W548 HydrophobicContact CD1-CZ3 4.34Å; L441-W548 HydrophobicContact CD2-CB 3.97Å; L441-W548 HydrophobicContact CD2-CD2 3.7Å; L441-W548 HydrophobicContact CD2-CE3 3.86Å; L441-W548 HydrophobicContact CD2-CG 3.77Å; L441-W548 HydrophobicContact CG-CB 4.42Å; L441-W548 HydrophobicContact CG-CD2 3.63Å; L441-W548 HydrophobicContact CG-CE3 4.14Å; L441-W548 HydrophobicContact CG-CG 3.76Å; L441-W548 HydrophobicContact CG-CZ2 4.39Å; L441-M550 HydrophobicContact CD2-CG 4.09Å; L441-M550 HydrophobicContact CD2-SD 4.35Å; L441-F589 HydrophobicContact CD1-CE2 4.32Å; L441-F589 HydrophobicContact CD1-CZ 4.11Å
442P81.9Confident82.6Confident50 Ų5079.3 Ų79.333%0.32541%0.409SS..  trans-54.6145.2175.5-26.733000112.2E444 L445 T446 M550P442-E444 PolarHBondContact O-N 3.12Å; P442-E444 VanDerWaalsContact O-N 3.16Å; P442-L445 PolarHBondContact O-N 2.88Å; P442-T446 PolarHBondContact O-N 2.84Å; P442-T446 PolarHBondContact O-OG1 2.71Å; P442-M550 WeakPolarHBondContact CD-SD 3.49Å; P442-M550 HydrophobicContact CG-CE 3.77Å; P442-M550 HydrophobicContact CG-SD 3.38Å; P442-M550 WeakPolarHBondContact CG-SD 3.34Å
443E82.5Confident83.7Confident157 Ų15778.9 Ų78.973%0.73440%0.401SS*.Hα-helixtrans-56.9-29.8174-69.8-172167.200112L445 T446 N447 S448E443-L445 VanDerWaalsContact C-N 3.28Å; E443-L445 PolarHBondContact O-N 2.89Å; E443-T446 WeakPolarHBondContact CA-OG1 3.37Å; E443-T446 PolarHBondContact O-N 3.46Å; E443-N447 CarbonylContact O-C 3.56Å; E443-N447 WeakPolarHBondContact O-CA 3.44Å; E443-N447 PolarHBondContact O-N 2.81Å; E443-S448 PolarHBondContact O-N 2.74Å
444E80.9Confident84.4Confident94 Ų9476.3 Ų76.344%0.43939%0.388SS..Hα-helixtrans-61.7-34.5176.4-171.5171.9-157.500112.4P442 S448 K450 Y451P442-E444 PolarHBondContact O-N 3.12Å; P442-E444 VanDerWaalsContact O-N 3.16Å; E444-S448 WeakPolarHBondContact O-CB 3.33Å; E444-S448 PolarHBondContact O-OG 2.87Å; E444-K450 WeakPolarHBondContact OE1-CD 3.49Å; E444-K450 IonicContact OE1-NZ 3.86Å; E444-K450 PolarHBondContact OE1-NZ 3.32Å; E444-Y451 HydrophobicContact CG-CD2 4.27Å; E444-Y451 HydrophobicContact CG-CE2 4.04Å
445L83.2Confident85Confident10 Ų1068.2 Ų68.25%0.05236%0.358CS..Hα-helixtrans-82.1-33.4177.8-72.3175.9000112.5P442 E443 Y451 H505 M550 F589P442-L445 PolarHBondContact O-N 2.88Å; E443-L445 VanDerWaalsContact C-N 3.28Å; E443-L445 PolarHBondContact O-N 2.89Å; L445-Y451 HydrophobicContact CD2-CD2 3.9Å; L445-Y451 HydrophobicContact CD2-CE2 4.38Å; L445-Y451 HydrophobicContact CD2-CG 4.05Å; L445-H505 HydrophobicContact CD2-CB 4.37Å; L445-M550 HydrophobicContact CD1-SD 4.1Å; L445-F589 HydrophobicContact CB-CD1 4.32Å; L445-F589 HydrophobicContact CB-CE1 4.12Å; L445-F589 HydrophobicContact CB-CE2 4.46Å; L445-F589 HydrophobicContact CB-CZ 4.19Å; L445-F589 HydrophobicContact CD1-CD2 4.49Å; L445-F589 HydrophobicContact CD2-CB 4.31Å; L445-F589 HydrophobicContact CD2-CD1 4.48Å; L445-F589 HydrophobicContact CD2-CD2 4.43Å; L445-F589 HydrophobicContact CD2-CG 4.16Å; L445-F589 WeakPolarHBondContact O-CD1 3.38Å; L445-F589 WeakPolarHBondContact O-CE1 3.35Å
446T81.8Confident85.4Confident68 Ų6873.9 Ų73.942%0.41739%0.388SS..Hα-helixtrans-95.1-33.2-169.951.80000113.6L441 P442 E443L441-T446 HydrophobicContact CB-CG2 3.71Å; L441-T446 HydrophobicContact CD1-CG2 4.24Å; P442-T446 PolarHBondContact O-N 2.84Å; P442-T446 PolarHBondContact O-OG1 2.71Å; E443-T446 WeakPolarHBondContact CA-OG1 3.37Å; E443-T446 PolarHBondContact O-N 3.46Å
447N74.1Confident85.7Confident134 Ų13471.7 Ų71.772%0.71738%0.381SS*.SBendtrans-130.612.8-169.7-152.714.9000113.9E443E443-N447 CarbonylContact O-C 3.56Å; E443-N447 WeakPolarHBondContact O-CA 3.44Å; E443-N447 PolarHBondContact O-N 2.81Å
448S70.6Confident86Confident21 Ų2171.2 Ų71.215%0.14738%0.378CS..  trans-91.9159.2174.682.70000113.5E443 E444 K450 Y451 K592E443-S448 PolarHBondContact O-N 2.74Å; E444-S448 WeakPolarHBondContact O-CB 3.33Å; E444-S448 PolarHBondContact O-OG 2.87Å; S448-K450 PolarHBondContact O-N 2.84Å; S448-K450 WeakPolarHBondContact OG-CB 3.36Å; S448-K450 PolarHBondContact OG-N 3.13Å; S448-Y451 PolarHBondContact OG-N 3.38Å; S448-K592 PolarHBondContact O-NZ 2.96Å
449D78.2Confident86.2Confident146 Ų14675.8 Ų75.878%0.78140%0.397SS*.SBendtrans-74.8-1.8166.1-69-33.7000113.2K592D449-K592 WeakPolarHBondContact O-CB 3.47Å
450K81.6Confident86.6Confident122 Ų12271.8 Ų71.853%0.5337%0.367SS..SBendtrans-89.6-34.2-177-61.9-176-172.9170.60113.2E444 S448 P591 K592E444-K450 WeakPolarHBondContact OE1-CD 3.49Å; E444-K450 IonicContact OE1-NZ 3.86Å; E444-K450 PolarHBondContact OE1-NZ 3.32Å; S448-K450 PolarHBondContact O-N 2.84Å; S448-K450 WeakPolarHBondContact OG-CB 3.36Å; S448-K450 PolarHBondContact OG-N 3.13Å; K450-P591 CarbonylContact O-C 3.48Å; K450-P591 VanDerWaalsContact O-CA 3.28Å; K450-P591 WeakPolarHBondContact O-CA 3.24Å; K450-K592 PolarHBondContact O-N 3.12Å
451Y88.6Confident86.9Confident54 Ų5470.4 Ų70.421%0.21236%0.358CS..EExtended strand (participates in β ladder)trans-128.3147.7-173.1-56.2-72.2000112E444 L445 S448 S504 H505 G590 K592E444-Y451 HydrophobicContact CG-CD2 4.27Å; E444-Y451 HydrophobicContact CG-CE2 4.04Å; L445-Y451 HydrophobicContact CD2-CD2 3.9Å; L445-Y451 HydrophobicContact CD2-CE2 4.38Å; L445-Y451 HydrophobicContact CD2-CG 4.05Å; S448-Y451 PolarHBondContact OG-N 3.38Å; Y451-S504 WeakPolarHBondContact CD1-OG 3.47Å; Y451-H505 AromaticContact CE1-CE1 3.98Å; Y451-H505 AromaticContact CZ-CE1 3.93Å; Y451-G590 CarbonylContact C-O 3.58Å; Y451-G590 VanDerWaalsContact CA-O 3.28Å; Y451-G590 WeakPolarHBondContact CA-O 3.4Å; Y451-K592 WeakPolarHBondContact O-CD 3.32Å; Y451-K592 WeakPolarHBondContact O-CE 3.34Å; Y451-K592 WeakPolarHBondContact O-CG 3.39Å; Y451-K592 PolarHBondContact O-NZ 2.69Å
452K91.3Very high87.2Confident78 Ų7870.6 Ų70.634%0.33936%0.36SS..EExtended strand (participates in β ladder)trans-126.3145.4167.655.6162.8-167146.20109.6I454 D457 F589 G590 K592K452-I454 HydrophobicContact CD-CG2 3.97Å; K452-I454 VanDerWaalsContact CE-CG2 3.5Å; K452-I454 HydrophobicContact CG-CG2 3.82Å; K452-D457 IonicContact NZ-OD2 2.96Å; K452-D457 PolarHBondContact NZ-OD2 2.86Å; K452-F589 CarbonylContact O-C 3.59Å; K452-F589 VanDerWaalsContact O-CA 3.28Å; K452-F589 WeakPolarHBondContact O-CA 3.37Å; K452-G590 PolarHBondContact N-O 2.88Å; K452-G590 PolarHBondContact O-N 2.78Å; K452-K592 HydrophobicContact CB-CD 4.32Å; K452-K592 HydrophobicContact CB-CG 3.62Å; K452-K592 HydrophobicContact CG-CG 3.95Å
453E92.6Very high87.8Confident51 Ų5170.7 Ų70.724%0.23836%0.361CS..EExtended strand (participates in β ladder)trans-64.5135.3164.1-145.2-71.8154.600108.2G455 R475 R587 I588 F589E453-G455 VanDerWaalsContact CD-N 3.28Å; E453-G455 PolarHBondContact OE1-N 3.34Å; E453-G455 WeakPolarHBondContact OE2-CA 3.31Å; E453-G455 PolarHBondContact OE2-N 3.18Å; E453-R475 IonicContact OE1-CZ 2.68Å; E453-R475 IonicContact OE1-NH1 3.85Å; E453-R475 PolarHBondContact OE1-NH1 3.02Å; E453-R475 IonicContact OE1-NH2 2.74Å; E453-R475 PolarHBondContact OE1-NH2 3.49Å; E453-R475 IonicContact OE2-NH2 3.42Å; E453-R475 PolarHBondContact OE2-NH2 2.93Å; E453-R475 VanDerWaalsContact OE2-NH2 3.15Å; E453-R587 HydrophobicContact CG-CB 4.38Å; E453-I588 CarbonylContact C-O 3.54Å; E453-I588 WeakPolarHBondContact CA-O 3.35Å; E453-I588 PolarHBondContact OE1-N 3.36Å; E453-F589 HydrophobicContact CB-CD1 4.36Å; E453-F589 HydrophobicContact CB-CE1 4.15Å; E453-F589 HydrophobicContact CG-CE1 4.18Å; E453-F589 HydrophobicContact CG-CZ 4.33Å
454I93.3Very high88.3Confident3 Ų365.5 Ų65.52%0.01534%0.34CS..  trans-129.810.6-176.658.5169.3000112K452 D456 D457 F497 T501 V503 I588K452-I454 HydrophobicContact CD-CG2 3.97Å; K452-I454 VanDerWaalsContact CE-CG2 3.5Å; K452-I454 HydrophobicContact CG-CG2 3.82Å; I454-D456 VanDerWaalsContact C-N 3.3Å; I454-D457 WeakPolarHBondContact O-CB 3.47Å; I454-D457 PolarHBondContact O-N 2.93Å; I454-F497 HydrophobicContact CD1-CE1 3.92Å; I454-F497 HydrophobicContact CD1-CZ 4.03Å; I454-F497 HydrophobicContact CG1-CE1 4.21Å; I454-F497 HydrophobicContact CG1-CZ 4.48Å; I454-T501 HydrophobicContact CD1-CG2 3.74Å; I454-V503 HydrophobicContact CD1-CB 4.49Å; I454-V503 HydrophobicContact CD1-CG1 4.5Å; I454-V503 HydrophobicContact CD1-CG2 3.97Å; I454-I588 HydrophobicContact CD1-CG2 4.02Å; I454-I588 HydrophobicContact CG1-CB 4.36Å; I454-I588 HydrophobicContact CG1-CG2 3.84Å; I454-I588 WeakPolarHBondContact CG1-O 2.97Å; I454-I588 PolarHBondContact N-O 3.13Å
455G91.5Very high88.9Confident1 Ų163.9 Ų63.91%0.0134%0.339CS..SBendtrans-68-31.2178.700000112.3E453 D457 A458 W460E453-G455 VanDerWaalsContact CD-N 3.28Å; E453-G455 PolarHBondContact OE1-N 3.34Å; E453-G455 WeakPolarHBondContact OE2-CA 3.31Å; E453-G455 PolarHBondContact OE2-N 3.18Å; G455-D457 VanDerWaalsContact C-N 3.26Å; G455-D457 PolarHBondContact O-N 2.75Å; G455-A458 PolarHBondContact O-N 3.42Å; G455-W460 PolarHBondContact O-NE1 3.2Å
456D92.1Very high89.4Confident136 Ų13666.2 Ų66.273%0.72735%0.349SS*.THydrogen-bonded Turntrans-75.7-16.2175.9-59.7-19.7000112.6I454 A458 R475I454-D456 VanDerWaalsContact C-N 3.3Å; D456-A458 PolarHBondContact O-N 3.09Å; D456-R475 IonicContact OD1-CZ 2.86Å; D456-R475 IonicContact OD1-NH2 2.72Å; D456-R475 PolarHBondContact OD1-NH2 3.46Å
457D90.5Very high89.8Confident81 Ų8168.8 Ų68.843%0.43337%0.366SS..THydrogen-bonded Turntrans-82.27.9173.6-68.5-30000112K452 I454 G455K452-D457 IonicContact NZ-OD2 2.96Å; K452-D457 PolarHBondContact NZ-OD2 2.86Å; I454-D457 WeakPolarHBondContact O-CB 3.47Å; I454-D457 PolarHBondContact O-N 2.93Å; G455-D457 VanDerWaalsContact C-N 3.26Å; G455-D457 PolarHBondContact O-N 2.75Å
458A94.1Very high90.7Very high13 Ų1365.2 Ų65.211%0.10736%0.361CS..EExtended strand (participates in β ladder)trans-134.6151.9-170.400000113.4G455 D456 W460 I495 F496 F497G455-A458 PolarHBondContact O-N 3.42Å; D456-A458 PolarHBondContact O-N 3.09Å; A458-W460 VanDerWaalsContact O-CD1 3.25Å; A458-I495 HydrophobicContact CB-CG2 3.39Å; A458-F496 CarbonylContact C-O 3.56Å; A458-F496 VanDerWaalsContact CA-O 3.24Å; A458-F496 WeakPolarHBondContact CA-O 3.44Å; A458-F496 WeakPolarHBondContact CB-O 3.36Å; A458-F497 HydrophobicContact CB-CD1 3.75Å; A458-F497 HydrophobicContact CB-CE1 3.68Å; A458-F497 HydrophobicContact CB-CG 4.4Å; A458-F497 HydrophobicContact CB-CZ 4.25Å
459E95.3Very high91.8Very high141 Ų14168.4 Ų68.466%0.65937%0.371SS*.EExtended strand (participates in β ladder)trans-91.4137.2170.8-68.6-65.7165.600110F496E459-F496 HydrophobicContact CB-CB 4.27Å; E459-F496 PolarHBondContact N-O 2.93Å; E459-F496 PolarHBondContact O-N 2.86Å
460W96.7Very high92.6Very high27 Ų2762 Ų6210%0.10234%0.339CS..EExtended strand (participates in β ladder)trans-117130.2-173.7-65.770.3000111G455 A458 V471 L474 I493 N494 I495 V586 I588G455-W460 PolarHBondContact O-NE1 3.2Å; A458-W460 VanDerWaalsContact O-CD1 3.25Å; W460-V471 HydrophobicContact CB-CG1 3.66Å; W460-V471 HydrophobicContact CB-CG2 4.07Å; W460-V471 HydrophobicContact CG-CG1 4.28Å; W460-L474 HydrophobicContact CE3-CD2 4.11Å; W460-L474 HydrophobicContact CZ3-CD2 4.14Å; W460-I493 HydrophobicContact CE3-CG2 3.5Å; W460-I493 VanDerWaalsContact CE3-CG2 3.5Å; W460-I493 HydrophobicContact CZ3-CG2 3.65Å; W460-N494 CarbonylContact C-O 3.44Å; W460-N494 WeakPolarHBondContact CA-O 3.28Å; W460-I495 HydrophobicContact CD2-CG1 3.69Å; W460-I495 HydrophobicContact CD2-CG2 4.44Å; W460-I495 HydrophobicContact CE3-CD1 4.18Å; W460-I495 HydrophobicContact CE3-CG1 3.4Å; W460-I495 HydrophobicContact CH2-CD1 4.12Å; W460-I495 HydrophobicContact CH2-CG1 3.62Å; W460-I495 HydrophobicContact CZ2-CG1 3.88Å; W460-I495 HydrophobicContact CZ2-CG2 4.21Å; W460-I495 HydrophobicContact CZ3-CD1 3.77Å; W460-I495 HydrophobicContact CZ3-CG1 3.36Å; W460-V586 HydrophobicContact CH2-CB 4.21Å; W460-V586 HydrophobicContact CH2-CG1 3.74Å; W460-V586 HydrophobicContact CZ3-CB 4.1Å; W460-V586 HydrophobicContact CZ3-CG1 3.81Å; W460-I588 HydrophobicContact CH2-CD1 3.47Å; W460-I588 VanDerWaalsContact CH2-CD1 3.47Å; W460-I588 HydrophobicContact CH2-CG1 3.88Å; W460-I588 HydrophobicContact CZ2-CD1 3.79Å; W460-I588 HydrophobicContact CZ2-CG1 4.27Å; W460-I588 HydrophobicContact CZ3-CD1 4.3Å
461V95.5Very high93.2Very high75 Ų7558.4 Ų58.446%0.45533%0.328SS..EExtended strand (participates in β ladder)trans-130.1122.3178.3-175.70000109.6N494 F496V461-N494 HydrophobicContact CB-CB 4.36Å; V461-N494 PolarHBondContact N-O 3.16Å; V461-N494 WeakPolarHBondContact O-CB 3.31Å; V461-N494 PolarHBondContact O-N 2.92Å; V461-N494 PolarHBondContact O-ND2 2.92Å; V461-N494 VanDerWaalsContact O-ND2 3.13Å; V461-F496 HydrophobicContact CB-CE2 3.96Å; V461-F496 HydrophobicContact CG2-CD2 4.06Å; V461-F496 HydrophobicContact CG2-CE2 3.7Å
462L95.5Very high93.4Very high21 Ų2163 Ų6311%0.1135%0.351CS..EExtended strand (participates in β ladder)trans-90.5147.2175.7-55.9170.3000109.4T464 C465 V471 L474 W483 T492 I493L462-T464 VanDerWaalsContact C-N 3.3Å; L462-T464 PolarHBondContact O-N 3.2Å; L462-C465 HydrophobicContact CD1-CB 4.31Å; L462-V471 HydrophobicContact CD1-CB 4.42Å; L462-V471 HydrophobicContact CD1-CG2 3.64Å; L462-V471 HydrophobicContact CD2-CG2 4.37Å; L462-V471 HydrophobicContact CG-CG2 3.63Å; L462-L474 HydrophobicContact CD2-CD2 4.11Å; L462-W483 HydrophobicContact CB-CZ2 4.31Å; L462-W483 HydrophobicContact CD1-CD2 4.34Å; L462-W483 HydrophobicContact CD1-CG 3.96Å; L462-W483 HydrophobicContact CD2-CD2 3.98Å; L462-W483 HydrophobicContact CD2-CE3 4.32Å; L462-W483 HydrophobicContact CD2-CG 4.36Å; L462-W483 HydrophobicContact CD2-CZ2 4.19Å; L462-T492 CarbonylContact C-O 3.53Å; L462-T492 WeakPolarHBondContact CA-O 3.28Å; L462-I493 HydrophobicContact CD2-CB 4.19Å; L462-I493 HydrophobicContact CD2-CG1 3.82Å; L462-I493 HydrophobicContact CD2-CG2 3.96Å
463S93.4Very high93.5Very high51 Ų5161 Ų6136%0.35734%0.343SS..SBendtrans-57.7-47.217448.90000111.6T492S463-T492 WeakPolarHBondContact CB-OG1 3.29Å; S463-T492 PolarHBondContact N-O 3.29Å; S463-T492 PolarHBondContact OG-N 3.15Å
464T93.8Very high93.5Very high49 Ų4958.5 Ų58.530%0.30133%0.331SS..  trans-156.1157-179.558.80000109.2L462 W483 D486L462-T464 VanDerWaalsContact C-N 3.3Å; L462-T464 PolarHBondContact O-N 3.2Å; T464-W483 PolarHBondContact O-NE1 2.76Å; T464-D486 WeakPolarHBondContact CB-O 3.07Å; T464-D486 WeakPolarHBondContact CG2-O 3.19Å; T464-D486 PolarHBondContact OG1-N 2.95Å; T464-D486 PolarHBondContact OG1-O 2.64Å
465C93.4Very high93.5Very high60 Ų6060.9 Ų60.941%0.40534%0.34SS..  trans-153145.4171.660.30000110.7L462 Y469 Q484L462-C465 HydrophobicContact CD1-CB 4.31Å; C465-Y469 WeakPolarHBondContact CB-O 3.28Å; C465-Q484 VanDerWaalsContact CA-O 3.26Å; C465-Q484 WeakPolarHBondContact CA-O 3.37Å
466K92.6Very high93.6Very high59 Ų5963.4 Ų63.426%0.25735%0.353SS..  trans-68.7149.4167.6-67.9-168.5-174159.80109.9G468 Y469 Q484 D486 D580K466-G468 PolarHBondContact O-N 2.79Å; K466-Y469 HydrophobicContact CB-CD2 4Å; K466-Y469 PolarHBondContact O-N 2.8Å; K466-Q484 HydrophobicContact CD-CG 4.07Å; K466-Q484 HydrophobicContact CG-CG 4.28Å; K466-Q484 PolarHBondContact N-O 3.28Å; K466-D486 HydrophobicContact CG-CB 3.84Å; K466-D580 IonicContact NZ-OD2 3.25Å; K466-D580 PolarHBondContact NZ-OD2 2.8Å
467P91.4Very high93.5Very high121 Ų12158.7 Ų58.779%0.78634%0.336SS*.THydrogen-bonded Turntrans-52.4125.2178.1-26.434.5000111.7Y469P467-Y469 WeakPolarHBondContact O-CD2 3.45Å
468G92.5Very high93.5Very high60 Ų6061 Ų6162%0.61934%0.343SS*.THydrogen-bonded Turntrans86.1-1.9-179.400000116.2K466 Q473K466-G468 PolarHBondContact O-N 2.79Å; G468-Q473 PolarHBondContact O-NE2 3.44Å; G468-Q473 PolarHBondContact O-OE1 3.45Å
469Y94.1Very high93.5Very high87 Ų8764.6 Ų64.634%0.34136%0.356SS..  trans-120.151.5179.5-60.4-89.9000110.8C465 K466 P467 Y482 W483 Q484C465-Y469 WeakPolarHBondContact CB-O 3.28Å; K466-Y469 HydrophobicContact CB-CD2 4Å; K466-Y469 PolarHBondContact O-N 2.8Å; P467-Y469 WeakPolarHBondContact O-CD2 3.45Å; Y469-Y482 AromaticContact CD1-CD2 3.9Å; Y469-Y482 HydrophobicContact CD1-CD2 3.9Å; Y469-Y482 AromaticContact CD1-CE2 3.58Å; Y469-Y482 HydrophobicContact CD1-CE2 3.58Å; Y469-Y482 WeakPolarHBondContact CD1-O 3.3Å; Y469-Y482 HydrophobicContact CE1-CD2 4.33Å; Y469-Y482 HydrophobicContact CE1-CE1 4.25Å; Y469-Y482 AromaticContact CE1-CE2 3.63Å; Y469-Y482 HydrophobicContact CE1-CE2 3.63Å; Y469-Y482 AromaticContact CE1-CZ 3.58Å; Y469-W483 WeakPolarHBondContact O-CA 3.35Å; Y469-Q484 HydrophobicContact CD1-CB 4.37Å; Y469-Q484 HydrophobicContact CG-CB 4.06Å; Y469-Q484 PolarHBondContact O-N 3.29Å
470G94.2Very high93.3Very high12 Ų1264.8 Ų64.812%0.12436%0.362CS..SBendtrans-99.3-155.1-173.300000114.3Q472 Q473 L474G470-Q472 PolarHBondContact O-N 3.46Å; G470-Q473 PolarHBondContact O-N 2.97Å; G470-Q473 PolarHBondContact O-OE1 2.81Å; G470-L474 PolarHBondContact O-N 3.17Å
471V93.9Very high93.1Very high47 Ų4765.2 Ų65.229%0.28537%0.367SS..Hα-helixtrans-57.9-34.8179172.90000111.9W460 L462 Q473 L474 R475W460-V471 HydrophobicContact CB-CG1 3.66Å; W460-V471 HydrophobicContact CB-CG2 4.07Å; W460-V471 HydrophobicContact CG-CG1 4.28Å; L462-V471 HydrophobicContact CD1-CB 4.42Å; L462-V471 HydrophobicContact CD1-CG2 3.64Å; L462-V471 HydrophobicContact CD2-CG2 4.37Å; L462-V471 HydrophobicContact CG-CG2 3.63Å; V471-Q473 VanDerWaalsContact C-N 3.32Å; V471-Q473 PolarHBondContact O-N 2.95Å; V471-L474 WeakPolarHBondContact O-CB 3.47Å; V471-L474 PolarHBondContact O-N 2.75Å; V471-L474 VanDerWaalsContact O-N 3.12Å; V471-R475 HydrophobicContact CG1-CG 4.49Å; V471-R475 PolarHBondContact O-N 3.39Å
472Q92.9Very high93.1Very high151 Ų15163.9 Ų63.971%0.70635%0.354SS*.Hα-helixtrans-57.8-45.5-179.7-171.9177.613.400111.4G470 L474 R475 D476G470-Q472 PolarHBondContact O-N 3.46Å; Q472-L474 VanDerWaalsContact C-N 3.31Å; Q472-L474 PolarHBondContact O-N 2.71Å; Q472-R475 PolarHBondContact O-N 2.78Å; Q472-D476 VanDerWaalsContact O-CB 3.31Å; Q472-D476 WeakPolarHBondContact O-CB 3.33Å; Q472-D476 PolarHBondContact O-N 3.34Å
473Q94.3Very high93.1Very high34 Ų3462.9 Ų62.916%0.15935%0.349CS..Hα-helixtrans-69.3-29.4178.9-71.566.237.700112.1G468 G470 V471 R475 Y482 Q585G468-Q473 PolarHBondContact O-NE2 3.44Å; G468-Q473 PolarHBondContact O-OE1 3.45Å; G470-Q473 PolarHBondContact O-N 2.97Å; G470-Q473 PolarHBondContact O-OE1 2.81Å; V471-Q473 VanDerWaalsContact C-N 3.32Å; V471-Q473 PolarHBondContact O-N 2.95Å; Q473-R475 PolarHBondContact O-N 2.98Å; Q473-Y482 VanDerWaalsContact CB-O 3.28Å; Q473-Y482 WeakPolarHBondContact CB-O 3.33Å; Q473-Q585 PolarHBondContact O-NE2 2.79Å
474L92.9Very high93.2Very high0 Ų061.4 Ų61.40%034%0.337CS..Hα-helixtrans-70.1-20177-166.272.1000113.4W460 L462 G470 V471 Q472 W483 I493 V583 Q585 V586W460-L474 HydrophobicContact CE3-CD2 4.11Å; W460-L474 HydrophobicContact CZ3-CD2 4.14Å; L462-L474 HydrophobicContact CD2-CD2 4.11Å; G470-L474 PolarHBondContact O-N 3.17Å; V471-L474 WeakPolarHBondContact O-CB 3.47Å; V471-L474 PolarHBondContact O-N 2.75Å; V471-L474 VanDerWaalsContact O-N 3.12Å; Q472-L474 VanDerWaalsContact C-N 3.31Å; Q472-L474 PolarHBondContact O-N 2.71Å; L474-W483 HydrophobicContact CB-CB 4.37Å; L474-W483 HydrophobicContact CD1-CB 3.91Å; L474-W483 HydrophobicContact CD1-CE3 4.44Å; L474-I493 HydrophobicContact CD1-CD1 4.28Å; L474-I493 HydrophobicContact CD2-CD1 3.94Å; L474-I493 HydrophobicContact CD2-CG1 4.38Å; L474-I493 HydrophobicContact CD2-CG2 3.82Å; L474-V583 HydrophobicContact CD1-CB 3.72Å; L474-V583 HydrophobicContact CD1-CG1 3.53Å; L474-Q585 WeakPolarHBondContact O-CA 3.24Å; L474-Q585 PolarHBondContact O-OE1 3.13Å; L474-V586 HydrophobicContact CD1-CB 4.39Å; L474-V586 HydrophobicContact CD1-CG2 3.65Å; L474-V586 HydrophobicContact CD2-CB 4.29Å; L474-V586 HydrophobicContact CD2-CG2 4.11Å; L474-V586 HydrophobicContact CG-CB 4.15Å; L474-V586 HydrophobicContact CG-CG2 3.93Å; L474-V586 PolarHBondContact O-N 2.95Å; L474-V586 VanDerWaalsContact O-N 3.1Å
475R93.2Very high93.2Very high52 Ų5259 Ų5920%0.19632%0.322CS..Hα-helixtrans-127.7-2.4-167.5-69.7-67.6-60.7176.7-2.7114.6E453 D456 V471 Q472 Q473 G477 V586E453-R475 IonicContact OE1-CZ 2.68Å; E453-R475 IonicContact OE1-NH1 3.85Å; E453-R475 PolarHBondContact OE1-NH1 3.02Å; E453-R475 IonicContact OE1-NH2 2.74Å; E453-R475 PolarHBondContact OE1-NH2 3.49Å; E453-R475 IonicContact OE2-NH2 3.42Å; E453-R475 PolarHBondContact OE2-NH2 2.93Å; E453-R475 VanDerWaalsContact OE2-NH2 3.15Å; D456-R475 IonicContact OD1-CZ 2.86Å; D456-R475 IonicContact OD1-NH2 2.72Å; D456-R475 PolarHBondContact OD1-NH2 3.46Å; V471-R475 HydrophobicContact CG1-CG 4.49Å; V471-R475 PolarHBondContact O-N 3.39Å; Q472-R475 PolarHBondContact O-N 2.78Å; Q473-R475 PolarHBondContact O-N 2.98Å; R475-G477 PolarHBondContact O-N 3.48Å; R475-V586 WeakPolarHBondContact CD-O 3.44Å; R475-V586 PolarHBondContact NH1-O 2.82Å
476D92.3Very high93Very high55 Ų5560.2 Ų60.229%0.29432%0.324SS..SBendtrans-73.3-3.5-176.166.36.6000114.9Q472 K478 T481 Q585Q472-D476 VanDerWaalsContact O-CB 3.31Å; Q472-D476 WeakPolarHBondContact O-CB 3.33Å; Q472-D476 PolarHBondContact O-N 3.34Å; D476-K478 VanDerWaalsContact C-N 3.26Å; D476-K478 PolarHBondContact O-N 3.24Å; D476-K478 PolarHBondContact OD1-N 3.17Å; D476-T481 VanDerWaalsContact CG-OG1 3.22Å; D476-T481 PolarHBondContact OD1-OG1 2.79Å; D476-T481 WeakPolarHBondContact OD2-CB 3.17Å; D476-T481 WeakPolarHBondContact OD2-CG2 3.31Å; D476-T481 PolarHBondContact OD2-OG1 2.93Å; D476-Q585 PolarHBondContact OD1-NE2 3.39Å
477G90.5Very high92.7Very high36 Ų3658.6 Ų58.637%0.37132%0.324SS..SBendtrans74.57-179.300000115.2R475 Q585R475-G477 PolarHBondContact O-N 3.48Å; G477-Q585 VanDerWaalsContact CA-OE1 3.28Å
478K92.1Very high92.4Very high129 Ų12957.9 Ų57.956%0.56132%0.323SS*.  trans-99.6140.4179.6-61.2176.9-177.5177.10110.4D476 T481 Q585D476-K478 VanDerWaalsContact C-N 3.26Å; D476-K478 PolarHBondContact O-N 3.24Å; D476-K478 PolarHBondContact OD1-N 3.17Å; K478-T481 PolarHBondContact O-OG1 2.94Å; K478-Q585 PolarHBondContact O-NE2 3.36Å
479F92.1Very high92.1Very high90 Ų9058.3 Ų58.340%0.39531%0.308SS..SBendtrans-86.9-12.2177.7-59.9-58.2000113.1F509 W548 R584 Q585F479-F509 AromaticContact CD1-CD1 3.86Å; F479-F509 HydrophobicContact CD1-CD1 3.86Å; F479-F509 HydrophobicContact CD1-CD2 4.02Å; F479-F509 AromaticContact CD1-CE1 3.81Å; F479-F509 HydrophobicContact CD1-CE1 3.81Å; F479-F509 AromaticContact CD1-CE2 3.96Å; F479-F509 HydrophobicContact CD1-CE2 3.96Å; F479-F509 AromaticContact CD1-CG 3.94Å; F479-F509 HydrophobicContact CD1-CG 3.94Å; F479-F509 AromaticContact CD1-CZ 3.85Å; F479-F509 HydrophobicContact CD1-CZ 3.85Å; F479-F509 HydrophobicContact CE1-CD1 4.33Å; F479-F509 AromaticContact CE1-CD2 3.67Å; F479-F509 HydrophobicContact CE1-CD2 3.67Å; F479-F509 HydrophobicContact CE1-CE1 4.41Å; F479-F509 AromaticContact CE1-CE2 3.76Å; F479-F509 HydrophobicContact CE1-CE2 3.76Å; F479-F509 AromaticContact CE1-CG 3.94Å; F479-F509 HydrophobicContact CE1-CG 3.94Å; F479-F509 HydrophobicContact CE1-CZ 4.13Å; F479-F509 HydrophobicContact CG-CE1 4.35Å; F479-F509 HydrophobicContact CG-CZ 4.29Å; F479-F509 HydrophobicContact CZ-CE2 4.32Å; F479-W548 AromaticContact CE1-CZ2 3.84Å; F479-W548 HydrophobicContact CE1-CZ2 3.84Å; F479-W548 HydrophobicContact CZ-CZ2 4.25Å; F479-R584 WeakPolarHBondContact O-CD 3.38Å; F479-R584 PolarHBondContact O-NH1 3.33Å; F479-Q585 HydrophobicContact CD1-CG 4.17Å; F479-Q585 HydrophobicContact CE1-CG 4.23Å
480D91.7Very high92Very high144 Ų14457.2 Ų57.277%0.7731%0.312SS*.SBendtrans-86-15.8-179.6-57-35000113
481T93.6Very high92Very high37 Ų3756.7 Ų56.723%0.22731%0.306CS..  trans-100.8156.5176.652.30000110.5D476 K478 R584D476-T481 VanDerWaalsContact CG-OG1 3.22Å; D476-T481 PolarHBondContact OD1-OG1 2.79Å; D476-T481 WeakPolarHBondContact OD2-CB 3.17Å; D476-T481 WeakPolarHBondContact OD2-CG2 3.31Å; D476-T481 PolarHBondContact OD2-OG1 2.93Å; K478-T481 PolarHBondContact O-OG1 2.94Å; T481-R584 WeakPolarHBondContact O-CA 3.45Å
482Y94.8Very high92.1Very high46 Ų4655.3 Ų55.318%0.1830%0.298CS..  trans-153.4154.1-179.652.3-88.7000112.1Y469 Q473 Q484 H582 V583Y469-Y482 AromaticContact CD1-CD2 3.9Å; Y469-Y482 HydrophobicContact CD1-CD2 3.9Å; Y469-Y482 AromaticContact CD1-CE2 3.58Å; Y469-Y482 HydrophobicContact CD1-CE2 3.58Å; Y469-Y482 WeakPolarHBondContact CD1-O 3.3Å; Y469-Y482 HydrophobicContact CE1-CD2 4.33Å; Y469-Y482 HydrophobicContact CE1-CE1 4.25Å; Y469-Y482 AromaticContact CE1-CE2 3.63Å; Y469-Y482 HydrophobicContact CE1-CE2 3.63Å; Y469-Y482 AromaticContact CE1-CZ 3.58Å; Q473-Y482 VanDerWaalsContact CB-O 3.28Å; Q473-Y482 WeakPolarHBondContact CB-O 3.33Å; Y482-Q484 HydrophobicContact CD2-CB 4.08Å; Y482-Q484 HydrophobicContact CE2-CB 3.98Å; Y482-H582 HydrophobicContact CD2-CB 4.19Å; Y482-H582 AromaticContact CD2-CD2 3.78Å; Y482-H582 AromaticContact CD2-CG 3.72Å; Y482-H582 AromaticContact CD2-ND1 3.93Å; Y482-H582 AromaticContact CE2-CD2 3.76Å; Y482-H582 AromaticContact CE2-CE1 3.52Å; Y482-H582 AromaticContact CE2-CG 3.91Å; Y482-H582 AromaticContact CE2-ND1 3.76Å; Y482-H582 AromaticContact CE2-NE2 3.52Å; Y482-H582 HydrophobicContact CG-CB 4.49Å; Y482-H582 AromaticContact CZ-CE1 3.87Å; Y482-V583 WeakPolarHBondContact CA-O 3.5Å
483W95.2Very high92.4Very high0 Ų048.2 Ų48.20%027%0.265CS..EExtended strand (participates in β ladder)trans-74133.5157.716643.7000109L462 T464 Y469 L474 H491 I493 I571 H582 V583L462-W483 HydrophobicContact CB-CZ2 4.31Å; L462-W483 HydrophobicContact CD1-CD2 4.34Å; L462-W483 HydrophobicContact CD1-CG 3.96Å; L462-W483 HydrophobicContact CD2-CD2 3.98Å; L462-W483 HydrophobicContact CD2-CE3 4.32Å; L462-W483 HydrophobicContact CD2-CG 4.36Å; L462-W483 HydrophobicContact CD2-CZ2 4.19Å; T464-W483 PolarHBondContact O-NE1 2.76Å; Y469-W483 WeakPolarHBondContact O-CA 3.35Å; L474-W483 HydrophobicContact CB-CB 4.37Å; L474-W483 HydrophobicContact CD1-CB 3.91Å; L474-W483 HydrophobicContact CD1-CE3 4.44Å; W483-H491 HydrophobicContact CH2-CB 3.69Å; W483-H491 HydrophobicContact CZ2-CB 4.13Å; W483-I493 HydrophobicContact CE3-CD1 3.74Å; W483-I493 HydrophobicContact CE3-CG1 3.77Å; W483-I493 HydrophobicContact CH2-CD1 4.42Å; W483-I493 HydrophobicContact CH2-CG1 3.7Å; W483-I493 HydrophobicContact CZ3-CD1 3.48Å; W483-I493 VanDerWaalsContact CZ3-CD1 3.48Å; W483-I493 HydrophobicContact CZ3-CG1 3.23Å; W483-I571 HydrophobicContact CH2-CD1 4.23Å; W483-I571 HydrophobicContact CZ3-CD1 3.67Å; W483-H582 VanDerWaalsContact O-CA 3.32Å; W483-H582 WeakPolarHBondContact O-CA 3.38Å; W483-V583 HydrophobicContact CE3-CB 3.97Å; W483-V583 HydrophobicContact CE3-CG2 3.76Å; W483-V583 HydrophobicContact CZ3-CG2 4.02Å; W483-V583 PolarHBondContact N-O 3.24Å; W483-V583 PolarHBondContact O-N 2.81Å; W483-V583 VanDerWaalsContact O-N 3.07Å
484Q94.8Very high92.5Very high20 Ų2047 Ų479%0.09326%0.259CS..EExtended strand (participates in β ladder)trans-117.7117.7168.6-177.216813.800109.3C465 K466 Y469 Y482 S581 H582C465-Q484 VanDerWaalsContact CA-O 3.26Å; C465-Q484 WeakPolarHBondContact CA-O 3.37Å; K466-Q484 HydrophobicContact CD-CG 4.07Å; K466-Q484 HydrophobicContact CG-CG 4.28Å; K466-Q484 PolarHBondContact N-O 3.28Å; Y469-Q484 HydrophobicContact CD1-CB 4.37Å; Y469-Q484 HydrophobicContact CG-CB 4.06Å; Y469-Q484 PolarHBondContact O-N 3.29Å; Y482-Q484 HydrophobicContact CD2-CB 4.08Å; Y482-Q484 HydrophobicContact CE2-CB 3.98Å; Q484-S581 WeakPolarHBondContact CA-O 3.33Å; Q484-H582 PolarHBondContact NE2-NE2 2.67Å
485S94.8Very high92.7Very high0 Ų047 Ų470%026%0.259CS..  trans-67158.3173.368.80000111.7H491 D580 S581S485-H491 PolarHBondContact OG-CE1 3.13Å; S485-H491 PolarHBondContact OG-ND1 3.28Å; S485-H491 PolarHBondContact OG-NE2 3.17Å; S485-D580 WeakPolarHBondContact OG-CA 3.5Å; S485-S581 PolarHBondContact N-O 2.8Å; S485-S581 VanDerWaalsContact N-O 3.17Å; S485-S581 PolarHBondContact OG-N 3Å
486D89.6Confident92.8Very high84 Ų8447.2 Ų47.245%0.44926%0.262SS..  trans-140.788175-169.911.4000109.3T464 K466T464-D486 WeakPolarHBondContact CB-O 3.07Å; T464-D486 WeakPolarHBondContact CG2-O 3.19Å; T464-D486 PolarHBondContact OG1-N 2.95Å; T464-D486 PolarHBondContact OG1-O 2.64Å; K466-D486 HydrophobicContact CG-CB 3.84Å
487G85Confident93Very high25 Ų2545 Ų4526%0.25825%0.25SS..SBendtrans164.8-167.5-172.800000114.3H491G487-H491 PolarHBondContact O-NE2 3.18Å
488S86.9Confident93.1Very high107 Ų10749.5 Ų49.575%0.74827%0.27SS*.SBendtrans-90144.517355.70000111.1
489Q85.7Confident93.1Very high68 Ų6851.2 Ų51.232%0.31827%0.273SS..SBendtrans-61.1150.2169-73.5172.9-12.500111.6V572 N574 G578Q489-V572 PolarHBondContact OE1-O 2.5Å; Q489-N574 PolarHBondContact NE2-ND2 3.18Å; Q489-G578 PolarHBondContact NE2-O 2.88Å
490P91.8Very high93Very high65 Ų6553 Ų5342%0.42228%0.281SS..PPolyproline II helixcis-78.6133.22.231.1-33.8000113.1A570 I571P490-A570 HydrophobicContact CB-CB 4.28Å; P490-I571 WeakPolarHBondContact CA-O 3.31Å; P490-I571 WeakPolarHBondContact CB-O 3.36Å
491H94.7Very high93Very high0 Ų047.1 Ų47.10%025%0.25CS..EExtended strand (participates in β ladder)trans-80.2130.2171.6-49.9136.3000109W483 S485 G487 I571 R579 S581W483-H491 HydrophobicContact CH2-CB 3.69Å; W483-H491 HydrophobicContact CZ2-CB 4.13Å; S485-H491 PolarHBondContact OG-CE1 3.13Å; S485-H491 PolarHBondContact OG-ND1 3.28Å; S485-H491 PolarHBondContact OG-NE2 3.17Å; G487-H491 PolarHBondContact O-NE2 3.18Å; H491-I571 HydrophobicContact CB-CB 4.41Å; H491-I571 HydrophobicContact CB-CD1 4.47Å; H491-I571 PolarHBondContact N-O 2.85Å; H491-I571 PolarHBondContact O-N 2.74Å; H491-R579 PolarHBondContact CE1-O 3.01Å; H491-S581 WeakPolarHBondContact ND1-CB 3.33Å; H491-S581 PolarHBondContact ND1-OG 3.23Å
492T96.2Very high92.9Very high19 Ų1949.5 Ų49.512%0.11726%0.257CS..EExtended strand (participates in β ladder)trans-118.2139-171.266.20000112.8L462 S463 N494 Q568 I569 A570L462-T492 CarbonylContact C-O 3.53Å; L462-T492 WeakPolarHBondContact CA-O 3.28Å; S463-T492 WeakPolarHBondContact CB-OG1 3.29Å; S463-T492 PolarHBondContact N-O 3.29Å; S463-T492 PolarHBondContact OG-N 3.15Å; T492-N494 PolarHBondContact OG1-ND2 3.48Å; T492-Q568 HydrophobicContact CG2-CG 4.19Å; T492-I569 CarbonylContact C-O 3.58Å; T492-I569 WeakPolarHBondContact CA-O 3.49Å; T492-A570 HydrophobicContact CG2-CB 4.06Å
493I97.1Very high92.7Very high1 Ų147.3 Ų47.31%0.00525%0.249CC..EExtended strand (participates in β ladder)trans-112.2111.7166.6-51.1169.2000106.2W460 L462 L474 W483 I495 Q568 I569 V586W460-I493 HydrophobicContact CE3-CG2 3.5Å; W460-I493 VanDerWaalsContact CE3-CG2 3.5Å; W460-I493 HydrophobicContact CZ3-CG2 3.65Å; L462-I493 HydrophobicContact CD2-CB 4.19Å; L462-I493 HydrophobicContact CD2-CG1 3.82Å; L462-I493 HydrophobicContact CD2-CG2 3.96Å; L474-I493 HydrophobicContact CD1-CD1 4.28Å; L474-I493 HydrophobicContact CD2-CD1 3.94Å; L474-I493 HydrophobicContact CD2-CG1 4.38Å; L474-I493 HydrophobicContact CD2-CG2 3.82Å; W483-I493 HydrophobicContact CE3-CD1 3.74Å; W483-I493 HydrophobicContact CE3-CG1 3.77Å; W483-I493 HydrophobicContact CH2-CD1 4.42Å; W483-I493 HydrophobicContact CH2-CG1 3.7Å; W483-I493 HydrophobicContact CZ3-CD1 3.48Å; W483-I493 VanDerWaalsContact CZ3-CD1 3.48Å; W483-I493 HydrophobicContact CZ3-CG1 3.23Å; I493-I495 HydrophobicContact CG2-CD1 4.25Å; I493-Q568 CarbonylContact O-C 3.54Å; I493-Q568 WeakPolarHBondContact O-CA 3.46Å; I493-I569 HydrophobicContact CB-CB 4.19Å; I493-I569 HydrophobicContact CD1-CD1 4.45Å; I493-I569 PolarHBondContact N-O 3.05Å; I493-I569 PolarHBondContact O-N 2.86Å; I493-V586 HydrophobicContact CD1-CG2 3.97Å
494N97Very high92.5Very high8 Ų847.3 Ų47.34%0.04325%0.249CC..EExtended strand (participates in β ladder)trans-104.1124.1-178.4-55-72.2000109.2W460 V461 T492 F496 L531 Q568W460-N494 CarbonylContact C-O 3.44Å; W460-N494 WeakPolarHBondContact CA-O 3.28Å; V461-N494 HydrophobicContact CB-CB 4.36Å; V461-N494 PolarHBondContact N-O 3.16Å; V461-N494 WeakPolarHBondContact O-CB 3.31Å; V461-N494 PolarHBondContact O-N 2.92Å; V461-N494 PolarHBondContact O-ND2 2.92Å; V461-N494 VanDerWaalsContact O-ND2 3.13Å; T492-N494 PolarHBondContact OG1-ND2 3.48Å; N494-F496 HydrophobicContact CB-CD2 4.31Å; N494-F496 HydrophobicContact CB-CE2 3.5Å; N494-F496 HydrophobicContact CB-CZ 3.96Å; N494-L531 HydrophobicContact CB-CD2 4.25Å; N494-L531 WeakPolarHBondContact OD1-CD2 3.31Å; N494-Q568 VanDerWaalsContact OD1-CG 3.27Å; N494-Q568 WeakPolarHBondContact OD1-CG 3.45Å; N494-Q568 PolarHBondContact OD1-NE2 2.87Å
495I96.9Very high92.4Very high0 Ų048 Ų480%025%0.252CS..EExtended strand (participates in β ladder)trans-113.2115.2180-55.7107.6000108.4A458 W460 I493 F497 V566 I567 I569 I588A458-I495 HydrophobicContact CB-CG2 3.39Å; W460-I495 HydrophobicContact CD2-CG1 3.69Å; W460-I495 HydrophobicContact CD2-CG2 4.44Å; W460-I495 HydrophobicContact CE3-CD1 4.18Å; W460-I495 HydrophobicContact CE3-CG1 3.4Å; W460-I495 HydrophobicContact CH2-CD1 4.12Å; W460-I495 HydrophobicContact CH2-CG1 3.62Å; W460-I495 HydrophobicContact CZ2-CG1 3.88Å; W460-I495 HydrophobicContact CZ2-CG2 4.21Å; W460-I495 HydrophobicContact CZ3-CD1 3.77Å; W460-I495 HydrophobicContact CZ3-CG1 3.36Å; I493-I495 HydrophobicContact CG2-CD1 4.25Å; I495-F497 HydrophobicContact CG2-CE1 4.37Å; I495-F497 HydrophobicContact CG2-CE2 3.87Å; I495-F497 HydrophobicContact CG2-CZ 3.76Å; I495-V566 CarbonylContact O-C 3.53Å; I495-V566 WeakPolarHBondContact O-CA 3.49Å; I495-I567 HydrophobicContact CB-CB 4.43Å; I495-I567 HydrophobicContact CD1-CB 4.38Å; I495-I567 HydrophobicContact CD1-CG2 4.2Å; I495-I567 WeakPolarHBondContact CD1-O 3.34Å; I495-I567 PolarHBondContact N-O 3.45Å; I495-I567 PolarHBondContact O-N 3.05Å; I495-I569 HydrophobicContact CD1-CD1 4.14Å; I495-I569 HydrophobicContact CD1-CG1 4.18Å; I495-I588 HydrophobicContact CB-CD1 4.01Å; I495-I588 HydrophobicContact CD1-CD1 3.39Å; I495-I588 HydrophobicContact CG1-CD1 3.49Å; I495-I588 VanDerWaalsContact CG1-CD1 3.49Å; I495-I588 HydrophobicContact CG2-CD1 3.85Å
496F96.9Very high92.4Very high57 Ų5748 Ų4825%0.2525%0.252CS..EExtended strand (participates in β ladder)trans-105.4123-177.5-62.9-92.3000110.5A458 E459 V461 N494 L531 V566A458-F496 CarbonylContact C-O 3.56Å; A458-F496 VanDerWaalsContact CA-O 3.24Å; A458-F496 WeakPolarHBondContact CA-O 3.44Å; A458-F496 WeakPolarHBondContact CB-O 3.36Å; E459-F496 HydrophobicContact CB-CB 4.27Å; E459-F496 PolarHBondContact N-O 2.93Å; E459-F496 PolarHBondContact O-N 2.86Å; V461-F496 HydrophobicContact CB-CE2 3.96Å; V461-F496 HydrophobicContact CG2-CD2 4.06Å; V461-F496 HydrophobicContact CG2-CE2 3.7Å; N494-F496 HydrophobicContact CB-CD2 4.31Å; N494-F496 HydrophobicContact CB-CE2 3.5Å; N494-F496 HydrophobicContact CB-CZ 3.96Å; F496-L531 HydrophobicContact CE1-CD1 4.46Å; F496-L531 HydrophobicContact CE1-CD2 4.27Å; F496-L531 HydrophobicContact CE1-CG 3.98Å; F496-L531 HydrophobicContact CZ-CD1 3.85Å; F496-L531 HydrophobicContact CZ-CD2 3.86Å; F496-L531 HydrophobicContact CZ-CG 3.74Å; F496-V566 HydrophobicContact CD1-CB 4.44Å; F496-V566 HydrophobicContact CD1-CG1 4.18Å; F496-V566 HydrophobicContact CD1-CG2 3.54Å; F496-V566 HydrophobicContact CE1-CB 4.5Å; F496-V566 HydrophobicContact CE1-CG1 3.97Å; F496-V566 HydrophobicContact CE1-CG2 3.67Å; F496-V566 HydrophobicContact CZ-CG1 4.36Å
497F95.6Very high92.6Very high10 Ų1044 Ų444%0.04423%0.23CC..EExtended strand (participates in β ladder)trans-100135.4173.5-60.2-82.8000109.7I454 A458 I495 R499 T501 V503 F565 I567 I588I454-F497 HydrophobicContact CD1-CE1 3.92Å; I454-F497 HydrophobicContact CD1-CZ 4.03Å; I454-F497 HydrophobicContact CG1-CE1 4.21Å; I454-F497 HydrophobicContact CG1-CZ 4.48Å; A458-F497 HydrophobicContact CB-CD1 3.75Å; A458-F497 HydrophobicContact CB-CE1 3.68Å; A458-F497 HydrophobicContact CB-CG 4.4Å; A458-F497 HydrophobicContact CB-CZ 4.25Å; I495-F497 HydrophobicContact CG2-CE1 4.37Å; I495-F497 HydrophobicContact CG2-CE2 3.87Å; I495-F497 HydrophobicContact CG2-CZ 3.76Å; F497-R499 VanDerWaalsContact CB-O 3.23Å; F497-R499 WeakPolarHBondContact CB-O 3.49Å; F497-R499 PolarHBondContact O-N 3.17Å; F497-R499 VanDerWaalsContact O-N 3.12Å; F497-T501 HydrophobicContact CD1-CG2 3.86Å; F497-T501 HydrophobicContact CE1-CG2 4.01Å; F497-T501 HydrophobicContact CG-CG2 4.29Å; F497-V503 HydrophobicContact CE2-CG2 3.92Å; F497-V503 HydrophobicContact CZ-CG2 3.99Å; F497-F565 PolarHBondContact N-O 3.4Å; F497-I567 HydrophobicContact CE2-CG1 3.98Å; F497-I588 HydrophobicContact CZ-CG2 4.4Å
498T91.7Very high93.1Very high129 Ų12943 Ų4379%0.79122%0.219SC*.EExtended strand (participates in β ladder)trans-62-20.217753.30000113.5
499R92.4Very high93.5Very high165 Ų16538.9 Ų38.962%0.62319%0.188SC*.EExtended strand (participates in β ladder)trans-138.7160.617662.8-175.3175.5-149.9-7.3110.2F497 T501F497-R499 VanDerWaalsContact CB-O 3.23Å; F497-R499 WeakPolarHBondContact CB-O 3.49Å; F497-R499 PolarHBondContact O-N 3.17Å; F497-R499 VanDerWaalsContact O-N 3.12Å; R499-T501 PolarHBondContact O-N 2.69Å; R499-T501 PolarHBondContact O-OG1 3.37Å
500K89.7Confident93.8Very high128 Ų12835.7 Ų35.756%0.55717%0.173SC*.EExtended strand (participates in β ladder)trans-59.3102.5174.5-163.1171.3-171.3168.60110.4R563 F565K500-R563 HydrophobicContact CG-CB 4.27Å; K500-F565 HydrophobicContact CB-CD2 4.12Å; K500-F565 HydrophobicContact CB-CE1 4.36Å; K500-F565 HydrophobicContact CB-CE2 3.66Å; K500-F565 HydrophobicContact CB-CZ 3.8Å; K500-F565 HydrophobicContact CD-CE2 4.22Å; K500-F565 HydrophobicContact CG-CD2 4.27Å; K500-F565 HydrophobicContact CG-CE2 4.08Å; K500-F565 VanDerWaalsContact N-CE1 3.29Å
501T92.1Very high93.9Very high21 Ų2133.8 Ų33.813%0.12916%0.159CC..EExtended strand (participates in β ladder)trans-104.4144.7-169.6-64.40000110.6I454 F497 R499 R563 A564I454-T501 HydrophobicContact CD1-CG2 3.74Å; F497-T501 HydrophobicContact CD1-CG2 3.86Å; F497-T501 HydrophobicContact CE1-CG2 4.01Å; F497-T501 HydrophobicContact CG-CG2 4.29Å; R499-T501 PolarHBondContact O-N 2.69Å; R499-T501 PolarHBondContact O-OG1 3.37Å; T501-R563 WeakPolarHBondContact O-CA 3.34Å; T501-A564 PolarHBondContact N-O 3.18Å; T501-A564 PolarHBondContact O-N 3.19Å; T501-A564 VanDerWaalsContact O-N 3.11Å
502K91.5Very high93.7Very high86 Ų8635.5 Ų35.537%0.37417%0.17SC..EExtended strand (participates in β ladder)trans-85.2118.3174.3-71.2176.4-179.9-176.80108.9V561 V562 R563 G590 P591K502-V561 HydrophobicContact CB-CB 4.38Å; K502-V561 HydrophobicContact CB-CG2 4.06Å; K502-V561 HydrophobicContact CD-CG2 4.11Å; K502-V561 HydrophobicContact CG-CG2 4.03Å; K502-V562 CarbonylContact C-O 3.59Å; K502-V562 WeakPolarHBondContact CA-O 3.42Å; K502-R563 HydrophobicContact CG-CG 3.96Å; K502-G590 WeakPolarHBondContact O-CA 3.4Å; K502-P591 HydrophobicContact CB-CG 3.97Å; K502-P591 HydrophobicContact CD-CG 4.14Å; K502-P591 WeakPolarHBondContact O-CD 3.23Å
503V91.9Very high93.5Very high0 Ų042.1 Ų42.10%020%0.197CC..EExtended strand (participates in β ladder)trans-113.7125.4179-170.20000108.8I454 F497 L553 V561 V562 I567 I588I454-V503 HydrophobicContact CD1-CB 4.49Å; I454-V503 HydrophobicContact CD1-CG1 4.5Å; I454-V503 HydrophobicContact CD1-CG2 3.97Å; F497-V503 HydrophobicContact CE2-CG2 3.92Å; F497-V503 HydrophobicContact CZ-CG2 3.99Å; V503-L553 HydrophobicContact CB-CD1 4.2Å; V503-L553 HydrophobicContact CG1-CD1 3.72Å; V503-V561 CarbonylContact O-C 3.57Å; V503-V561 WeakPolarHBondContact O-CA 3.29Å; V503-V562 PolarHBondContact N-O 2.78Å; V503-V562 PolarHBondContact O-N 3.25Å; V503-I567 HydrophobicContact CG2-CD1 4.39Å; V503-I567 HydrophobicContact CG2-CG1 4.01Å; V503-I588 HydrophobicContact CG1-CG2 3.38Å
504S91Very high93.3Very high1 Ų146.3 Ų46.31%0.00722%0.223CC..  trans-100.1-40.5-178.866.30000112.8Y451 L553 F589Y451-S504 WeakPolarHBondContact CD1-OG 3.47Å; S504-L553 WeakPolarHBondContact O-CA 3.48Å; S504-L553 WeakPolarHBondContact O-CB 3.15Å; S504-L553 PolarHBondContact O-N 3.07Å; S504-F589 WeakPolarHBondContact CA-O 3.45Å; S504-F589 PolarHBondContact N-O 2.85Å; S504-F589 VanDerWaalsContact OG-C 3.28Å; S504-F589 PolarHBondContact OG-O 2.84Å
505H92.4Very high93.1Very high33 Ų3346.2 Ų46.215%0.15322%0.222CC..EExtended strand (participates in β ladder)trans-144.1145.6-175.6-6077.6000111L445 Y451 V551 I588 F589L445-H505 HydrophobicContact CD2-CB 4.37Å; Y451-H505 AromaticContact CE1-CE1 3.98Å; Y451-H505 AromaticContact CZ-CE1 3.93Å; H505-V551 VanDerWaalsContact CA-O 3.31Å; H505-V551 WeakPolarHBondContact CA-O 3.28Å; H505-I588 WeakPolarHBondContact O-CA 3.14Å; H505-F589 HydrophobicContact CB-CB 4.23Å; H505-F589 HydrophobicContact CB-CD2 4.39Å; H505-F589 PolarHBondContact N-O 2.78Å; H505-F589 VanDerWaalsContact N-O 3.17Å; H505-F589 PolarHBondContact O-N 3.31Å
506V94.4Very high92.8Very high0 Ų052.1 Ų52.10%025%0.25CC..EExtended strand (participates in β ladder)trans-115.2121.8165.3171.50000107.1I508 I525 V551 L553 I567 I569 I588V506-I508 HydrophobicContact CG1-CD1 4.4Å; V506-I508 HydrophobicContact CG1-CG1 4.15Å; V506-I525 HydrophobicContact CB-CD1 4.45Å; V506-I525 HydrophobicContact CG1-CD1 4.1Å; V506-V551 HydrophobicContact CB-CB 4.41Å; V506-V551 PolarHBondContact N-O 2.87Å; V506-V551 WeakPolarHBondContact O-CA 3.48Å; V506-V551 VanDerWaalsContact O-CB 3.31Å; V506-V551 WeakPolarHBondContact O-CB 3.48Å; V506-V551 PolarHBondContact O-N 3.46Å; V506-L553 HydrophobicContact CG2-CD1 3.87Å; V506-L553 HydrophobicContact CG2-CD2 4.45Å; V506-L553 HydrophobicContact CG2-CG 4.32Å; V506-I567 HydrophobicContact CG2-CG2 4.27Å; V506-I569 HydrophobicContact CG1-CD1 3.45Å; V506-I569 VanDerWaalsContact CG1-CD1 3.45Å; V506-I569 HydrophobicContact CG1-CG1 3.97Å; V506-I588 HydrophobicContact CG2-CG1 4.38Å
507C94.7Very high92.6Very high0 Ų050.7 Ų50.70%025%0.247CC..EExtended strand (participates in β ladder)trans-115.9129.1-178-640000109.2L441 W548 A549 V586 R587 F589L441-C507 HydrophobicContact CD2-CB 3.83Å; C507-W548 HydrophobicContact CB-CE3 3.89Å; C507-W548 HydrophobicContact CB-CZ3 4.08Å; C507-A549 WeakPolarHBondContact CA-O 3.38Å; C507-V586 CarbonylContact O-C 3.57Å; C507-V586 WeakPolarHBondContact O-CA 3.4Å; C507-R587 HydrophobicContact CB-CB 4.33Å; C507-R587 PolarHBondContact N-O 3.38Å; C507-R587 PolarHBondContact O-N 3.02Å; C507-F589 HydrophobicContact CB-CE2 4.28Å
508I94.7Very high92.4Very high4 Ų454.5 Ų54.52%0.02126%0.261CS..EExtended strand (participates in β ladder)trans-126.9128.9-177.6-53.9-178.7000108.1V506 T510 I523 A549 I569 V583 V586V506-I508 HydrophobicContact CG1-CD1 4.4Å; V506-I508 HydrophobicContact CG1-CG1 4.15Å; I508-T510 HydrophobicContact CG2-CG2 4.27Å; I508-I523 HydrophobicContact CD1-CD1 3.46Å; I508-I523 VanDerWaalsContact CD1-CD1 3.46Å; I508-A549 PolarHBondContact N-O 3.07Å; I508-A549 PolarHBondContact O-N 3.44Å; I508-I569 HydrophobicContact CD1-CD1 4.13Å; I508-I569 HydrophobicContact CD1-CG2 3.64Å; I508-I569 HydrophobicContact CG1-CD1 4.44Å; I508-V583 HydrophobicContact CG2-CG1 3.58Å; I508-V586 HydrophobicContact CG1-CG2 4.28Å; I508-V586 HydrophobicContact CG2-CG2 4.31Å
509F95.2Very high92.5Very high21 Ų2148.4 Ų48.49%0.09222%0.224CC..EExtended strand (participates in β ladder)trans-90.8126.5172.9-165.5-88.6000110.2F479 D511 W548 R584 Q585F479-F509 AromaticContact CD1-CD1 3.86Å; F479-F509 HydrophobicContact CD1-CD1 3.86Å; F479-F509 HydrophobicContact CD1-CD2 4.02Å; F479-F509 AromaticContact CD1-CE1 3.81Å; F479-F509 HydrophobicContact CD1-CE1 3.81Å; F479-F509 AromaticContact CD1-CE2 3.96Å; F479-F509 HydrophobicContact CD1-CE2 3.96Å; F479-F509 AromaticContact CD1-CG 3.94Å; F479-F509 HydrophobicContact CD1-CG 3.94Å; F479-F509 AromaticContact CD1-CZ 3.85Å; F479-F509 HydrophobicContact CD1-CZ 3.85Å; F479-F509 HydrophobicContact CE1-CD1 4.33Å; F479-F509 AromaticContact CE1-CD2 3.67Å; F479-F509 HydrophobicContact CE1-CD2 3.67Å; F479-F509 HydrophobicContact CE1-CE1 4.41Å; F479-F509 AromaticContact CE1-CE2 3.76Å; F479-F509 HydrophobicContact CE1-CE2 3.76Å; F479-F509 AromaticContact CE1-CG 3.94Å; F479-F509 HydrophobicContact CE1-CG 3.94Å; F479-F509 HydrophobicContact CE1-CZ 4.13Å; F479-F509 HydrophobicContact CG-CE1 4.35Å; F479-F509 HydrophobicContact CG-CZ 4.29Å; F479-F509 HydrophobicContact CZ-CE2 4.32Å; F509-D511 HydrophobicContact CE1-CB 4.33Å; F509-W548 HydrophobicContact CB-CD2 4.12Å; F509-W548 HydrophobicContact CB-CE3 4Å; F509-W548 HydrophobicContact CB-CH2 4.19Å; F509-W548 HydrophobicContact CB-CZ2 4.28Å; F509-W548 HydrophobicContact CB-CZ3 4.04Å; F509-W548 AromaticContact CD2-CD1 3.57Å; F509-W548 AromaticContact CD2-CD2 3.76Å; F509-W548 HydrophobicContact CD2-CD2 3.76Å; F509-W548 AromaticContact CD2-CE2 3.6Å; F509-W548 HydrophobicContact CD2-CE3 4.48Å; F509-W548 AromaticContact CD2-CG 3.78Å; F509-W548 HydrophobicContact CD2-CG 3.78Å; F509-W548 HydrophobicContact CD2-CZ2 4.23Å; F509-W548 AromaticContact CD2-NE1 3.45Å; F509-W548 AromaticContact CE2-CD1 3.91Å; F509-W548 HydrophobicContact CE2-CG 4.47Å; F509-W548 AromaticContact CE2-NE1 3.87Å; F509-W548 HydrophobicContact CG-CD2 4.45Å; F509-R584 HydrophobicContact CD1-CB 3.92Å; F509-Q585 HydrophobicContact CB-CB 3.96Å; F509-Q585 PolarHBondContact N-O 3.45Å
510T92.3Very high92.5Very high1 Ų140.6 Ų40.61%0.00620%0.195CC..EExtended strand (participates in β ladder)trans-124.4140.8179.255.20000109.6I508 T519 I542 P545 N546 G547I508-T510 HydrophobicContact CG2-CG2 4.27Å; T510-T519 HydrophobicContact CG2-CG2 4.35Å; T510-I542 HydrophobicContact CG2-CD1 4.13Å; T510-P545 CarbonylContact C-O 3.51Å; T510-P545 HydrophobicContact CG2-CB 4.32Å; T510-P545 WeakPolarHBondContact OG1-CA 3.41Å; T510-P545 WeakPolarHBondContact OG1-CB 3.38Å; T510-P545 PolarHBondContact OG1-O 3.39Å; T510-N546 CarbonylContact O-C 3.57Å; T510-N546 VanDerWaalsContact O-CA 3.3Å; T510-N546 WeakPolarHBondContact O-CA 3.48Å; T510-G547 PolarHBondContact N-O 2.94Å; T510-G547 PolarHBondContact O-N 3Å; T510-G547 PolarHBondContact OG1-O 2.72Å
511D93.1Very high92.6Very high25 Ų2536.1 Ų36.113%0.13418%0.177CC..EExtended strand (participates in β ladder)trans-133.588.7174.9-177.9-0.2000111F509 K513 T514 D515F509-D511 HydrophobicContact CE1-CB 4.33Å; D511-K513 PolarHBondContact O-N 3.02Å; D511-K513 WeakPolarHBondContact OD1-CB 3.4Å; D511-K513 PolarHBondContact OD1-N 3.41Å; D511-T514 PolarHBondContact O-N 2.82Å; D511-T514 PolarHBondContact OD1-N 3.07Å; D511-T514 WeakPolarHBondContact OD2-CB 3.41Å; D511-T514 PolarHBondContact OD2-OG1 2.78Å; D511-D515 WeakPolarHBondContact O-CB 2.84Å; D511-D515 PolarHBondContact O-N 3.12Å
512V91.6Very high92.6Very high36 Ų3639.9 Ų39.922%0.21819%0.189CC..Hα-helixtrans-62.4-21.717875.10000114.3E516 T519 P545 N546V512-E516 WeakPolarHBondContact O-CA 3.4Å; V512-E516 PolarHBondContact O-N 3.37Å; V512-E516 VanDerWaalsContact O-N 3.12Å; V512-T519 WeakPolarHBondContact CA-OG1 3.21Å; V512-T519 HydrophobicContact CB-CG2 4.18Å; V512-P545 HydrophobicContact CB-CG 4.05Å; V512-P545 WeakPolarHBondContact CB-O 3.43Å; V512-P545 HydrophobicContact CG2-CG 4.25Å; V512-P545 PolarHBondContact N-O 2.7Å; V512-N546 HydrophobicContact CG1-CB 4.23Å
513K91.6Very high92.7Very high159 Ų15935.8 Ų35.869%0.69117%0.171SC*.Hα-helixtrans-74-34.7-180-64.2-177.7177.1-177.50111.2D511D511-K513 PolarHBondContact O-N 3.02Å; D511-K513 WeakPolarHBondContact OD1-CB 3.4Å; D511-K513 PolarHBondContact OD1-N 3.41Å
514T92.5Very high92.7Very high89 Ų8935.8 Ų35.855%0.54617%0.171SC..Hα-helixtrans-96.8-37.7-178.3-48.30000112D511D511-T514 PolarHBondContact O-N 2.82Å; D511-T514 PolarHBondContact OD1-N 3.07Å; D511-T514 WeakPolarHBondContact OD2-CB 3.41Å; D511-T514 PolarHBondContact OD2-OG1 2.78Å
515D92Very high92.8Very high6 Ų635.8 Ų35.83%0.03217%0.171CC..Hα-helixtrans-94-11.8-175.3-62.5-42.1000113.5D511 S517 Y518 T519 H582 R584D511-D515 WeakPolarHBondContact O-CB 2.84Å; D511-D515 PolarHBondContact O-N 3.12Å; D515-S517 PolarHBondContact O-N 3.38Å; D515-S517 VanDerWaalsContact O-N 3.13Å; D515-Y518 WeakPolarHBondContact O-CB 3.46Å; D515-Y518 WeakPolarHBondContact O-CD2 3.46Å; D515-Y518 PolarHBondContact O-N 2.89Å; D515-T519 WeakPolarHBondContact CB-OG1 3.43Å; D515-H582 HydrophobicContact CB-CB 4Å; D515-H582 IonicContact OD1-CG 2.95Å; D515-H582 IonicContact OD1-ND1 3.15Å; D515-H582 PolarHBondContact OD1-ND1 2.91Å; D515-R584 IonicContact OD1-CZ 2.66Å; D515-R584 IonicContact OD1-NE 2.79Å; D515-R584 IonicContact OD1-NH2 2.8Å; D515-R584 PolarHBondContact OD1-NH2 3.2Å; D515-R584 IonicContact OD2-CZ 3.13Å; D515-R584 IonicContact OD2-NE 2.94Å; D515-R584 PolarHBondContact OD2-NE 3Å; D515-R584 IonicContact OD2-NH2 2.69Å; D515-R584 PolarHBondContact OD2-NH2 2.96Å
516E91.5Very high92.7Very high124 Ų12437.4 Ų37.458%0.57918%0.176SC*.G310 helixtrans45.3-116.3177.4-59.7-174.9171.500112.8V512 Y518 T519V512-E516 WeakPolarHBondContact O-CA 3.4Å; V512-E516 PolarHBondContact O-N 3.37Å; V512-E516 VanDerWaalsContact O-N 3.12Å; E516-Y518 VanDerWaalsContact C-N 3.27Å; E516-Y518 PolarHBondContact O-N 2.77Å; E516-T519 WeakPolarHBondContact O-CB 3.4Å; E516-T519 PolarHBondContact O-N 3.21Å; E516-T519 PolarHBondContact O-OG1 2.85Å
517S91.9Very high92.6Very high26 Ų2641.6 Ų41.618%0.18219%0.191CC..G310 helixtrans-68.6-17.6-179.368.50000114.4D515 T519 N574 H575 G578D515-S517 PolarHBondContact O-N 3.38Å; D515-S517 VanDerWaalsContact O-N 3.13Å; S517-T519 PolarHBondContact O-N 3.1Å; S517-N574 WeakPolarHBondContact O-CB 3.29Å; S517-H575 CarbonylContact C-O 3.47Å; S517-H575 VanDerWaalsContact CA-O 3.29Å; S517-H575 WeakPolarHBondContact CA-O 3.15Å; S517-G578 VanDerWaalsContact O-CA 3.31Å; S517-G578 WeakPolarHBondContact O-CA 3.34Å; S517-G578 PolarHBondContact O-N 3.21Å
518Y92.2Very high92.3Very high91 Ų9142 Ų4236%0.35720%0.196SC..G310 helixtrans-79.8-4.8177.7-57.7-77.1000112.8D515 E516 P520 D580 S581 H582D515-Y518 WeakPolarHBondContact O-CB 3.46Å; D515-Y518 WeakPolarHBondContact O-CD2 3.46Å; D515-Y518 PolarHBondContact O-N 2.89Å; E516-Y518 VanDerWaalsContact C-N 3.27Å; E516-Y518 PolarHBondContact O-N 2.77Å; Y518-P520 WeakPolarHBondContact O-CD 3.31Å; Y518-D580 HydrophobicContact CD1-CB 3.84Å; Y518-D580 WeakPolarHBondContact CD1-O 3.35Å; Y518-D580 HydrophobicContact CE1-CB 3.99Å; Y518-S581 CarbonylContact O-C 3.58Å; Y518-S581 VanDerWaalsContact O-CA 3.31Å; Y518-S581 WeakPolarHBondContact O-CA 2.95Å; Y518-H582 PolarHBondContact O-N 3.42Å
519T93.4Very high92.2Very high0 Ų046 Ų460%022%0.221CC..SBendtrans-77.8125.3-175.2-46.80000111.7T510 V512 D515 E516 S517 N521 P545 N574 H575T510-T519 HydrophobicContact CG2-CG2 4.35Å; V512-T519 WeakPolarHBondContact CA-OG1 3.21Å; V512-T519 HydrophobicContact CB-CG2 4.18Å; D515-T519 WeakPolarHBondContact CB-OG1 3.43Å; E516-T519 WeakPolarHBondContact O-CB 3.4Å; E516-T519 PolarHBondContact O-N 3.21Å; E516-T519 PolarHBondContact O-OG1 2.85Å; S517-T519 PolarHBondContact O-N 3.1Å; T519-N521 PolarHBondContact O-N 3.17Å; T519-P545 HydrophobicContact CG2-CB 3.69Å; T519-P545 HydrophobicContact CG2-CG 3.77Å; T519-N574 CarbonylContact O-C 3.55Å; T519-N574 WeakPolarHBondContact O-CA 3.49Å; T519-H575 WeakPolarHBondContact O-CB 3.39Å; T519-H575 PolarHBondContact O-N 2.96Å
520P93.3Very high91.9Very high2 Ų247.2 Ų47.21%0.01323%0.231CC..EExtended strand (participates in β ladder)trans-60.6133.5174.3-25.336000112.2Y518 I523 I571 N574 H582 V583Y518-P520 WeakPolarHBondContact O-CD 3.31Å; P520-I523 HydrophobicContact CB-CG2 4.18Å; P520-I571 HydrophobicContact CB-CD1 4.43Å; P520-I571 HydrophobicContact CB-CG1 4.29Å; P520-I571 HydrophobicContact CB-CG2 3.88Å; P520-I571 HydrophobicContact CG-CD1 3.8Å; P520-I571 HydrophobicContact CG-CG1 4.2Å; P520-I571 HydrophobicContact CG-CG2 4.14Å; P520-N574 WeakPolarHBondContact CA-OD1 3.46Å; P520-H582 VanDerWaalsContact CD-O 3.28Å; P520-H582 WeakPolarHBondContact CD-O 3.34Å; P520-V583 HydrophobicContact CG-CG2 3.99Å
521N91.8Very high91.8Very high34 Ų3451.1 Ų51.118%0.18225%0.252CS..EExtended strand (participates in β ladder)trans-118.7-21.1172.872.7-10000113.1T519 E541 I542 Q573T519-N521 PolarHBondContact O-N 3.17Å; N521-E541 CarbonylContact O-C 3.52Å; N521-E541 WeakPolarHBondContact O-CA 3.48Å; N521-I542 PolarHBondContact O-N 3.1Å; N521-Q573 PolarHBondContact N-O 2.79Å; N521-Q573 VanDerWaalsContact N-O 3.09Å; N521-Q573 WeakPolarHBondContact OD1-CB 3.39Å; N521-Q573 WeakPolarHBondContact OD1-CG 3.35Å; N521-Q573 PolarHBondContact OD1-O 3.47Å
522R91.7Very high91.6Very high99 Ų9956 Ų5637%0.37429%0.287SS..EExtended strand (participates in β ladder)trans-136120.9177.6-160176-178.7177.70.7110.8L539 V540 V572 Q573R522-L539 HydrophobicContact CG-CD1 4.3Å; R522-L539 HydrophobicContact CG-CG 4.39Å; R522-V540 WeakPolarHBondContact CA-O 3.43Å; R522-V572 PolarHBondContact O-N 2.98Å; R522-Q573 HydrophobicContact CB-CB 3.86Å; R522-Q573 PolarHBondContact N-O 2.78Å; R522-Q573 PolarHBondContact O-N 2.87Å
523I93.4Very high91.4Very high1 Ų157.5 Ų57.51%0.00529%0.293CS..EExtended strand (participates in β ladder)trans-127.7146.6-178.165.6178.7000110.7I508 P520 I525 L539 V540 I542 V551 A570 I571I508-I523 HydrophobicContact CD1-CD1 3.46Å; I508-I523 VanDerWaalsContact CD1-CD1 3.46Å; P520-I523 HydrophobicContact CB-CG2 4.18Å; I523-I525 HydrophobicContact CD1-CD1 4.26Å; I523-L539 WeakPolarHBondContact O-CD1 3.42Å; I523-V540 HydrophobicContact CD1-CB 4.07Å; I523-V540 HydrophobicContact CD1-CG1 4.27Å; I523-V540 HydrophobicContact CD1-CG2 4.45Å; I523-V540 HydrophobicContact CG1-CB 3.56Å; I523-V540 HydrophobicContact CG1-CG1 4.16Å; I523-V540 HydrophobicContact CG1-CG2 4.19Å; I523-V540 PolarHBondContact N-O 2.66Å; I523-V540 PolarHBondContact O-N 2.74Å; I523-I542 HydrophobicContact CD1-CD1 4.36Å; I523-V551 HydrophobicContact CD1-CG2 4.2Å; I523-A570 CarbonylContact C-O 3.6Å; I523-A570 VanDerWaalsContact CA-O 3.3Å; I523-A570 WeakPolarHBondContact CA-O 3.4Å; I523-I571 HydrophobicContact CG2-CG1 4.09Å
524S91.7Very high91.2Very high0 Ų051.9 Ų51.90%027%0.271CS..EExtended strand (participates in β ladder)trans-109.9121.2173170.10000108.2R526 Q536 A570S524-R526 WeakPolarHBondContact OG-CG 3.44Å; S524-R526 PolarHBondContact OG-NE 2.74Å; S524-Q536 VanDerWaalsContact OG-CD 3.29Å; S524-Q536 PolarHBondContact OG-OE1 2.95Å; S524-A570 PolarHBondContact N-O 2.83Å; S524-A570 PolarHBondContact O-N 2.99Å
525I92.9Very high90.8Very high0 Ų049.8 Ų49.80%026%0.259CS..EExtended strand (participates in β ladder)trans-92.9124.4172-54.1-58.8000107.8V506 I523 V537 C538 V540 V551 L553 I567 Q568 I569V506-I525 HydrophobicContact CB-CD1 4.45Å; V506-I525 HydrophobicContact CG1-CD1 4.1Å; I523-I525 HydrophobicContact CD1-CD1 4.26Å; I525-V537 WeakPolarHBondContact O-CB 3.32Å; I525-V537 PolarHBondContact O-N 3.34Å; I525-C538 PolarHBondContact N-O 2.87Å; I525-C538 PolarHBondContact O-N 2.83Å; I525-V540 HydrophobicContact CG1-CG2 4.44Å; I525-V551 HydrophobicContact CG1-CG1 4.16Å; I525-L553 HydrophobicContact CB-CD2 4.4Å; I525-L553 HydrophobicContact CG1-CD2 4.45Å; I525-L553 HydrophobicContact CG2-CD1 4.37Å; I525-L553 HydrophobicContact CG2-CD2 3.83Å; I525-I567 HydrophobicContact CG2-CG2 4.3Å; I525-Q568 WeakPolarHBondContact CA-O 3.26Å; I525-I569 HydrophobicContact CD1-CB 4.27Å; I525-I569 HydrophobicContact CD1-CG1 3.93Å; I525-I569 HydrophobicContact CD1-CG2 4.03Å
526R91.9Very high90.4Very high68 Ų6851.7 Ų51.726%0.25727%0.268SS..EExtended strand (participates in β ladder)trans-124.4156.1-178.8-45.9-179.2-177.4163.3-13.3110.7S524 L534 S535 Q536 I567 Q568S524-R526 WeakPolarHBondContact OG-CG 3.44Å; S524-R526 PolarHBondContact OG-NE 2.74Å; R526-L534 HydrophobicContact CB-CB 4.3Å; R526-L534 HydrophobicContact CB-CD2 4.43Å; R526-S535 CarbonylContact C-O 3.59Å; R526-S535 WeakPolarHBondContact CA-O 3.4Å; R526-S535 WeakPolarHBondContact CB-O 3.46Å; R526-Q536 HydrophobicContact CG-CB 4.26Å; R526-I567 CarbonylContact O-C 3.57Å; R526-I567 WeakPolarHBondContact O-CA 3.38Å; R526-Q568 HydrophobicContact CB-CB 4.26Å; R526-Q568 PolarHBondContact N-O 3.07Å; R526-Q568 PolarHBondContact O-N 2.8Å
527R91.5Very high90Very high88 Ų8847.2 Ų47.233%0.33225%0.249SC..EExtended strand (participates in β ladder)trans-136.7149.117873.9175.4-175125.9-1.3111.8L534 S535 V537 V562 R563 A564 V566 I567R527-L534 WeakPolarHBondContact O-CA 3.48Å; R527-S535 PolarHBondContact N-O 3.31Å; R527-S535 PolarHBondContact O-N 3.24Å; R527-S535 PolarHBondContact O-OG 2.84Å; R527-S535 VanDerWaalsContact O-OG 3.1Å; R527-V537 HydrophobicContact CB-CG2 3.84Å; R527-V537 HydrophobicContact CG-CG2 3.57Å; R527-V562 HydrophobicContact CB-CG1 4.05Å; R527-V562 HydrophobicContact CG-CG1 4.29Å; R527-R563 PolarHBondContact NH1-O 2.82Å; R527-A564 HydrophobicContact CB-CB 3.88Å; R527-V566 CarbonylContact C-O 3.45Å; R527-V566 VanDerWaalsContact CA-O 3.24Å; R527-V566 WeakPolarHBondContact CA-O 3.43Å; R527-I567 HydrophobicContact CB-CD1 3.87Å
528G89.2Confident89.7Confident9 Ų946.3 Ų46.39%0.09324%0.243CC..EExtended strand (participates in β ladder)trans-158.5177.8176.400000112.9F565 V566G528-F565 PolarHBondContact O-N 2.86Å; G528-V566 PolarHBondContact N-O 3.35Å; G528-V566 PolarHBondContact O-N 3.44Å
529T90.6Very high89.3Confident88 Ų8843 Ų4354%0.5423%0.231SC..SBendtrans-84.4-22.8162.364.20000111.7D533 F565T529-D533 WeakPolarHBondContact CB-OD2 3.38Å; T529-D533 PolarHBondContact N-OD1 3.15Å; T529-D533 VanDerWaalsContact N-OD1 3.12Å; T529-D533 PolarHBondContact N-OD2 2.75Å; T529-D533 VanDerWaalsContact OG1-CG 3.22Å; T529-D533 PolarHBondContact OG1-OD1 3.04Å; T529-D533 PolarHBondContact OG1-OD2 2.88Å; T529-F565 HydrophobicContact CG2-CD2 4.27Å; T529-F565 WeakPolarHBondContact O-CB 3.45Å
530S90.2Very high89.1Confident45 Ų4543 Ų4332%0.31523%0.231SC..SBendtrans-148.5-176.4179.272.50000109.8C532 D533S530-C532 VanDerWaalsContact C-N 3.29Å; S530-C532 PolarHBondContact OG-N 3.3Å; S530-C532 VanDerWaalsContact OG-N 3.1Å; S530-D533 WeakPolarHBondContact CA-OD1 3.4Å; S530-D533 PolarHBondContact N-OD1 3.18Å; S530-D533 PolarHBondContact OG-OD1 2.85Å
531L90.6Very high88.8Confident83 Ų8345.3 Ų45.344%0.43524%0.242SC..SBendtrans-74-20.4169.6-69.9178.8000113.1N494 F496 L534 V566N494-L531 HydrophobicContact CB-CD2 4.25Å; N494-L531 WeakPolarHBondContact OD1-CD2 3.31Å; F496-L531 HydrophobicContact CE1-CD1 4.46Å; F496-L531 HydrophobicContact CE1-CD2 4.27Å; F496-L531 HydrophobicContact CE1-CG 3.98Å; F496-L531 HydrophobicContact CZ-CD1 3.85Å; F496-L531 HydrophobicContact CZ-CD2 3.86Å; F496-L531 HydrophobicContact CZ-CG 3.74Å; L531-L534 HydrophobicContact CD2-CD1 3.9Å; L531-V566 HydrophobicContact CD2-CG1 3.99Å
532C88.4Confident88.7Confident129 Ų12944 Ų4487%0.87224%0.235SC*.THydrogen-bonded Turntrans-81.8-18-174.4-580000113.4S530S530-C532 VanDerWaalsContact C-N 3.29Å; S530-C532 PolarHBondContact OG-N 3.3Å; S530-C532 VanDerWaalsContact OG-N 3.1Å
533D87.3Confident88.2Confident66 Ų6644.6 Ų44.635%0.35324%0.237SC..THydrogen-bonded Turntrans-12025.8-177.471.5-41.4000112.1T529 S530 S535T529-D533 WeakPolarHBondContact CB-OD2 3.38Å; T529-D533 PolarHBondContact N-OD1 3.15Å; T529-D533 VanDerWaalsContact N-OD1 3.12Å; T529-D533 PolarHBondContact N-OD2 2.75Å; T529-D533 VanDerWaalsContact OG1-CG 3.22Å; T529-D533 PolarHBondContact OG1-OD1 3.04Å; T529-D533 PolarHBondContact OG1-OD2 2.88Å; S530-D533 WeakPolarHBondContact CA-OD1 3.4Å; S530-D533 PolarHBondContact N-OD1 3.18Å; S530-D533 PolarHBondContact OG-OD1 2.85Å; D533-S535 PolarHBondContact O-N 2.84Å
534L88.3Confident87.7Confident42 Ų4252.1 Ų52.122%0.2227%0.272CS..  trans-62.1123.5177.7-71.5175.3000110.9R526 R527 L531 V566 Q568R526-L534 HydrophobicContact CB-CB 4.3Å; R526-L534 HydrophobicContact CB-CD2 4.43Å; R527-L534 WeakPolarHBondContact O-CA 3.48Å; L531-L534 HydrophobicContact CD2-CD1 3.9Å; L534-V566 HydrophobicContact CD2-CB 4.25Å; L534-V566 HydrophobicContact CD2-CG1 4.07Å; L534-Q568 HydrophobicContact CD1-CB 3.96Å; L534-Q568 VanDerWaalsContact CD1-CD 3.49Å; L534-Q568 HydrophobicContact CD1-CG 4.35Å; L534-Q568 VanDerWaalsContact CD1-NE2 3.33Å; L534-Q568 HydrophobicContact CD2-CB 4.29Å
535S82.5Confident87.4Confident44 Ų4452.5 Ų52.531%0.30828%0.275SS..EExtended strand (participates in β ladder)trans-111133.6171.957.30000109.4R526 R527 D533R526-S535 CarbonylContact C-O 3.59Å; R526-S535 WeakPolarHBondContact CA-O 3.4Å; R526-S535 WeakPolarHBondContact CB-O 3.46Å; R527-S535 PolarHBondContact N-O 3.31Å; R527-S535 PolarHBondContact O-N 3.24Å; R527-S535 PolarHBondContact O-OG 2.84Å; R527-S535 VanDerWaalsContact O-OG 3.1Å; D533-S535 PolarHBondContact O-N 2.84Å
536Q84.5Confident87.3Confident47 Ų4755.6 Ų55.622%0.2229%0.291CS..EExtended strand (participates in β ladder)trans-65.5138.1174.9179.4170.8-60.500109.7Y430 S524 R526Y430-Q536 WeakPolarHBondContact CD1-O 3.38Å; Y430-Q536 HydrophobicContact CD2-CB 3.68Å; Y430-Q536 HydrophobicContact CD2-CG 3.7Å; Y430-Q536 HydrophobicContact CE1-CB 4.48Å; Y430-Q536 WeakPolarHBondContact CE1-O 3.34Å; Y430-Q536 HydrophobicContact CE2-CB 3.58Å; Y430-Q536 HydrophobicContact CE2-CG 4.15Å; Y430-Q536 HydrophobicContact CG-CB 4.16Å; Y430-Q536 HydrophobicContact CG-CG 3.92Å; Y430-Q536 VanDerWaalsContact CZ-O 3.3Å; S524-Q536 VanDerWaalsContact OG-CD 3.29Å; S524-Q536 PolarHBondContact OG-OE1 2.95Å; R526-Q536 HydrophobicContact CG-CB 4.26Å
537V83.7Confident87.4Confident29 Ų2952.4 Ų52.418%0.17628%0.28CS..EExtended strand (participates in β ladder)trans-97.1-50.8177.4176.70000109.1I525 R527 V562I525-V537 WeakPolarHBondContact O-CB 3.32Å; I525-V537 PolarHBondContact O-N 3.34Å; R527-V537 HydrophobicContact CB-CG2 3.84Å; R527-V537 HydrophobicContact CG-CG2 3.57Å; V537-V562 HydrophobicContact CG1-CG2 3.88Å; V537-V562 HydrophobicContact CG2-CG2 4.38Å
538C84.2Confident87.5Confident7 Ų748.6 Ų48.65%0.04727%0.265CS..EExtended strand (participates in β ladder)trans-152.8158176.958.60000109.9L433 I525L433-C538 HydrophobicContact CD1-CB 4.13Å; L433-C538 HydrophobicContact CG-CB 4.4Å; I525-C538 PolarHBondContact N-O 2.87Å; I525-C538 PolarHBondContact O-N 2.83Å
539L85Confident87.7Confident21 Ų2148.2 Ų48.211%0.1126%0.261CS..EExtended strand (participates in β ladder)trans-99145.3162.1-167.870000107.5P431 C432 L433 R522 I523P431-L539 PolarHBondContact O-N 2.93Å; C432-L539 CarbonylContact C-O 3.57Å; C432-L539 VanDerWaalsContact CA-O 3.3Å; C432-L539 WeakPolarHBondContact CA-O 3.39Å; C432-L539 HydrophobicContact CB-CB 4.44Å; L433-L539 PolarHBondContact N-O 3.17Å; R522-L539 HydrophobicContact CG-CD1 4.3Å; R522-L539 HydrophobicContact CG-CG 4.39Å; I523-L539 WeakPolarHBondContact O-CD1 3.42Å
540V88.3Confident87.7Confident0 Ų046 Ų460%025%0.245CC..EExtended strand (participates in β ladder)trans-128.8131.5179.5179.50000108.9L433 I435 R522 I523 I525 I542 V551L433-V540 HydrophobicContact CB-CG2 4.36Å; L433-V540 CarbonylContact O-C 3.53Å; L433-V540 VanDerWaalsContact O-CA 3.3Å; L433-V540 WeakPolarHBondContact O-CA 3.16Å; I435-V540 HydrophobicContact CB-CG1 4.29Å; I435-V540 HydrophobicContact CD1-CG1 3.48Å; I435-V540 VanDerWaalsContact CD1-CG1 3.48Å; I435-V540 HydrophobicContact CD1-CG2 4.35Å; I435-V540 HydrophobicContact CG1-CG1 3.84Å; R522-V540 WeakPolarHBondContact CA-O 3.43Å; I523-V540 HydrophobicContact CD1-CB 4.07Å; I523-V540 HydrophobicContact CD1-CG1 4.27Å; I523-V540 HydrophobicContact CD1-CG2 4.45Å; I523-V540 HydrophobicContact CG1-CB 3.56Å; I523-V540 HydrophobicContact CG1-CG1 4.16Å; I523-V540 HydrophobicContact CG1-CG2 4.19Å; I523-V540 PolarHBondContact N-O 2.66Å; I523-V540 PolarHBondContact O-N 2.74Å; I525-V540 HydrophobicContact CG1-CG2 4.44Å; V540-I542 HydrophobicContact CG1-CG1 4.19Å; V540-V551 HydrophobicContact CB-CG2 4.49Å; V540-V551 HydrophobicContact CG1-CG2 4.13Å; V540-V551 HydrophobicContact CG2-CB 4.33Å; V540-V551 HydrophobicContact CG2-CG1 3.49Å; V540-V551 VanDerWaalsContact CG2-CG1 3.49Å; V540-V551 HydrophobicContact CG2-CG2 3.85Å
541E87.6Confident87.7Confident52 Ų5243.9 Ų43.924%0.24323%0.23CC..EExtended strand (participates in β ladder)trans-111.1115171.7-166.9-168.2155.400108L433 R434 I435 N521 R543L433-E541 PolarHBondContact O-N 2.76Å; R434-E541 WeakPolarHBondContact CA-O 3.38Å; R434-E541 HydrophobicContact CG-CB 4.34Å; R434-E541 IonicContact NE-OE2 3.52Å; R434-E541 PolarHBondContact NE-OE2 2.8Å; I435-E541 PolarHBondContact N-O 3.37Å; N521-E541 CarbonylContact O-C 3.52Å; N521-E541 WeakPolarHBondContact O-CA 3.48Å; E541-R543 PolarHBondContact O-N 3.03Å; E541-R543 IonicContact OE1-CZ 3.12Å; E541-R543 IonicContact OE1-NE 3.92Å; E541-R543 PolarHBondContact OE1-NE 3.15Å; E541-R543 IonicContact OE1-NH2 2.65Å; E541-R543 PolarHBondContact OE1-NH2 2.9Å; E541-R543 IonicContact OE2-NH2 2.8Å
542I89Confident87.6Confident7 Ų741.8 Ų41.84%0.03622%0.222CC..EExtended strand (participates in β ladder)trans-89107.7-178.4-51.7174.6000108.1C437 T510 N521 I523 V540 P545 A549C437-I542 WeakPolarHBondContact SG-CG2 3.45Å; T510-I542 HydrophobicContact CG2-CD1 4.13Å; N521-I542 PolarHBondContact O-N 3.1Å; I523-I542 HydrophobicContact CD1-CD1 4.36Å; V540-I542 HydrophobicContact CG1-CG1 4.19Å; I542-P545 HydrophobicContact CB-CB 4.3Å; I542-P545 HydrophobicContact CG2-CB 3.68Å; I542-A549 HydrophobicContact CD1-CB 3.79Å; I542-A549 HydrophobicContact CG1-CB 4.06Å; I542-A549 HydrophobicContact CG2-CB 3.99Å
543R82.5Confident87.4Confident111 Ų11135.7 Ų35.742%0.41918%0.181SC..EExtended strand (participates in β ladder)trans-85125176.7-68.6-85.8169.9149.9-4.8107.9I435 E541I435-R543 PolarHBondContact O-N 2.9Å; E541-R543 PolarHBondContact O-N 3.03Å; E541-R543 IonicContact OE1-CZ 3.12Å; E541-R543 IonicContact OE1-NE 3.92Å; E541-R543 PolarHBondContact OE1-NE 3.15Å; E541-R543 IonicContact OE1-NH2 2.65Å; E541-R543 PolarHBondContact OE1-NH2 2.9Å; E541-R543 IonicContact OE2-NH2 2.8Å
544Q82.7Confident86.5Confident159 Ų15939.6 Ų39.674%0.74320%0.197SC*.SBendtrans54.171.9-175.7-60.2176.7-20.600112N546Q544-N546 PolarHBondContact O-N 2.95Å
545P84.5Confident84.9Confident8 Ų838.8 Ų38.85%0.05219%0.194CC..  trans-72.271.4-171.327.5-30000112.6T510 V512 T519 I542T510-P545 CarbonylContact C-O 3.51Å; T510-P545 HydrophobicContact CG2-CB 4.32Å; T510-P545 WeakPolarHBondContact OG1-CA 3.41Å; T510-P545 WeakPolarHBondContact OG1-CB 3.38Å; T510-P545 PolarHBondContact OG1-O 3.39Å; V512-P545 HydrophobicContact CB-CG 4.05Å; V512-P545 WeakPolarHBondContact CB-O 3.43Å; V512-P545 HydrophobicContact CG2-CG 4.25Å; V512-P545 PolarHBondContact N-O 2.7Å; T519-P545 HydrophobicContact CG2-CB 3.69Å; T519-P545 HydrophobicContact CG2-CG 3.77Å; I542-P545 HydrophobicContact CB-CB 4.3Å; I542-P545 HydrophobicContact CG2-CB 3.68Å
546N91.3Very high82.9Confident64 Ų6439 Ų3934%0.34219%0.194SC..EExtended strand (participates in β ladder)trans-135.7100.9179.7-175.722000109.8C437 T510 V512 Q544C437-N546 WeakPolarHBondContact CB-O 3.42Å; T510-N546 CarbonylContact O-C 3.57Å; T510-N546 VanDerWaalsContact O-CA 3.3Å; T510-N546 WeakPolarHBondContact O-CA 3.48Å; V512-N546 HydrophobicContact CG1-CB 4.23Å; Q544-N546 PolarHBondContact O-N 2.95Å
547G93.5Very high80.8Confident2 Ų238.9 Ų38.92%0.02120%0.199CC..EExtended strand (participates in β ladder)trans111-162.6-171.900000113.5T438 T510 A549T438-G547 CarbonylContact O-C 3.52Å; T438-G547 WeakPolarHBondContact O-CA 3.47Å; T510-G547 PolarHBondContact N-O 2.94Å; T510-G547 PolarHBondContact O-N 3Å; T510-G547 PolarHBondContact OG1-O 2.72Å; G547-A549 PolarHBondContact O-N 3.28Å
548W94Very high79Confident8 Ų839 Ų393%0.0320%0.199CC..EExtended strand (participates in β ladder)trans-76.8113177.3-71.699.1000112.2C437 T438 L441 F479 C507 F509 Q585 R587C437-W548 VanDerWaalsContact CA-O 3.32Å; C437-W548 WeakPolarHBondContact CA-O 3.39Å; T438-W548 PolarHBondContact N-O 3.45Å; T438-W548 PolarHBondContact O-N 2.87Å; T438-W548 PolarHBondContact OG1-O 3.07Å; L441-W548 HydrophobicContact CD1-CD2 4.05Å; L441-W548 HydrophobicContact CD1-CE3 4.26Å; L441-W548 HydrophobicContact CD1-CH2 4.22Å; L441-W548 HydrophobicContact CD1-CZ2 4.02Å; L441-W548 HydrophobicContact CD1-CZ3 4.34Å; L441-W548 HydrophobicContact CD2-CB 3.97Å; L441-W548 HydrophobicContact CD2-CD2 3.7Å; L441-W548 HydrophobicContact CD2-CE3 3.86Å; L441-W548 HydrophobicContact CD2-CG 3.77Å; L441-W548 HydrophobicContact CG-CB 4.42Å; L441-W548 HydrophobicContact CG-CD2 3.63Å; L441-W548 HydrophobicContact CG-CE3 4.14Å; L441-W548 HydrophobicContact CG-CG 3.76Å; L441-W548 HydrophobicContact CG-CZ2 4.39Å; F479-W548 AromaticContact CE1-CZ2 3.84Å; F479-W548 HydrophobicContact CE1-CZ2 3.84Å; F479-W548 HydrophobicContact CZ-CZ2 4.25Å; C507-W548 HydrophobicContact CB-CE3 3.89Å; C507-W548 HydrophobicContact CB-CZ3 4.08Å; F509-W548 HydrophobicContact CB-CD2 4.12Å; F509-W548 HydrophobicContact CB-CE3 4Å; F509-W548 HydrophobicContact CB-CH2 4.19Å; F509-W548 HydrophobicContact CB-CZ2 4.28Å; F509-W548 HydrophobicContact CB-CZ3 4.04Å; F509-W548 AromaticContact CD2-CD1 3.57Å; F509-W548 AromaticContact CD2-CD2 3.76Å; F509-W548 HydrophobicContact CD2-CD2 3.76Å; F509-W548 AromaticContact CD2-CE2 3.6Å; F509-W548 HydrophobicContact CD2-CE3 4.48Å; F509-W548 AromaticContact CD2-CG 3.78Å; F509-W548 HydrophobicContact CD2-CG 3.78Å; F509-W548 HydrophobicContact CD2-CZ2 4.23Å; F509-W548 AromaticContact CD2-NE1 3.45Å; F509-W548 AromaticContact CE2-CD1 3.91Å; F509-W548 HydrophobicContact CE2-CG 4.47Å; F509-W548 AromaticContact CE2-NE1 3.87Å; F509-W548 HydrophobicContact CG-CD2 4.45Å; W548-Q585 HydrophobicContact CH2-CB 3.59Å; W548-Q585 HydrophobicContact CZ2-CB 4.24Å; W548-Q585 HydrophobicContact CZ3-CB 4.25Å; W548-R587 HydrophobicContact CH2-CG 3.93Å; W548-R587 HydrophobicContact CZ3-CB 4.45Å; W548-R587 HydrophobicContact CZ3-CG 4.26Å
549A92.9Very high77.5Confident0 Ų047.4 Ų47.40%024%0.238CC..EExtended strand (participates in β ladder)trans-82.3114.5162.100000109.3C507 I508 I542 G547C507-A549 WeakPolarHBondContact CA-O 3.38Å; I508-A549 PolarHBondContact N-O 3.07Å; I508-A549 PolarHBondContact O-N 3.44Å; I542-A549 HydrophobicContact CD1-CB 3.79Å; I542-A549 HydrophobicContact CG1-CB 4.06Å; I542-A549 HydrophobicContact CG2-CB 3.99Å; G547-A549 PolarHBondContact O-N 3.28Å
550M91Very high76.4Confident42 Ų4247.8 Ų47.821%0.20725%0.247CC..EExtended strand (participates in β ladder)trans-104.2111.6-177.4-59.4179-70.500110.5I435 T438 L441 P442 L445 P552I435-M550 VanDerWaalsContact CD1-O 3.26Å; I435-M550 WeakPolarHBondContact CD1-O 3.21Å; T438-M550 HydrophobicContact CG2-CE 4.01Å; L441-M550 HydrophobicContact CD2-CG 4.09Å; L441-M550 HydrophobicContact CD2-SD 4.35Å; P442-M550 WeakPolarHBondContact CD-SD 3.49Å; P442-M550 HydrophobicContact CG-CE 3.77Å; P442-M550 HydrophobicContact CG-SD 3.38Å; P442-M550 WeakPolarHBondContact CG-SD 3.34Å; L445-M550 HydrophobicContact CD1-SD 4.1Å; M550-P552 WeakPolarHBondContact O-CD 3.48Å
551V90.4Very high75.8Confident0 Ų048.5 Ų48.50%025%0.251CS..EExtended strand (participates in β ladder)trans-97.5104.9179.6-168.60000109.7L433 I435 H505 V506 I523 I525 V540 L553L433-V551 HydrophobicContact CD1-CG1 4.12Å; I435-V551 HydrophobicContact CD1-CB 4.11Å; I435-V551 HydrophobicContact CD1-CG1 4.22Å; I435-V551 HydrophobicContact CD1-CG2 3.81Å; H505-V551 VanDerWaalsContact CA-O 3.31Å; H505-V551 WeakPolarHBondContact CA-O 3.28Å; V506-V551 HydrophobicContact CB-CB 4.41Å; V506-V551 PolarHBondContact N-O 2.87Å; V506-V551 WeakPolarHBondContact O-CA 3.48Å; V506-V551 VanDerWaalsContact O-CB 3.31Å; V506-V551 WeakPolarHBondContact O-CB 3.48Å; V506-V551 PolarHBondContact O-N 3.46Å; I523-V551 HydrophobicContact CD1-CG2 4.2Å; I525-V551 HydrophobicContact CG1-CG1 4.16Å; V540-V551 HydrophobicContact CB-CG2 4.49Å; V540-V551 HydrophobicContact CG1-CG2 4.13Å; V540-V551 HydrophobicContact CG2-CB 4.33Å; V540-V551 HydrophobicContact CG2-CG1 3.49Å; V540-V551 VanDerWaalsContact CG2-CG1 3.49Å; V540-V551 HydrophobicContact CG2-CG2 3.85Å; V551-L553 HydrophobicContact CG1-CD2 4Å; V551-L553 PolarHBondContact O-N 3Å
552P87.5Confident75.7Confident40 Ų4046 Ų4626%0.2624%0.24SC..EExtended strand (participates in β ladder)trans-71.8123.5171.730.9-34.3000109.6M550 Q554M550-P552 WeakPolarHBondContact O-CD 3.48Å; P552-Q554 VanDerWaalsContact C-N 3.27Å; P552-Q554 HydrophobicContact CB-CG 4.29Å; P552-Q554 PolarHBondContact O-N 3.38Å; P552-Q554 VanDerWaalsContact O-N 3.15Å
553L85.1Confident75.6Confident1 Ų151 Ų511%0.00526%0.258CS..  trans-89.967175.9-56.7-166.5000109.7V503 S504 V506 I525 V551 C555 V562V503-L553 HydrophobicContact CB-CD1 4.2Å; V503-L553 HydrophobicContact CG1-CD1 3.72Å; S504-L553 WeakPolarHBondContact O-CA 3.48Å; S504-L553 WeakPolarHBondContact O-CB 3.15Å; S504-L553 PolarHBondContact O-N 3.07Å; V506-L553 HydrophobicContact CG2-CD1 3.87Å; V506-L553 HydrophobicContact CG2-CD2 4.45Å; V506-L553 HydrophobicContact CG2-CG 4.32Å; I525-L553 HydrophobicContact CB-CD2 4.4Å; I525-L553 HydrophobicContact CG1-CD2 4.45Å; I525-L553 HydrophobicContact CG2-CD1 4.37Å; I525-L553 HydrophobicContact CG2-CD2 3.83Å; V551-L553 HydrophobicContact CG1-CD2 4Å; V551-L553 PolarHBondContact O-N 3Å; L553-C555 PolarHBondContact O-N 3.37Å; L553-V562 HydrophobicContact CB-CB 4.27Å; L553-V562 HydrophobicContact CB-CG2 3.81Å; L553-V562 HydrophobicContact CD1-CB 4.28Å; L553-V562 HydrophobicContact CD1-CG2 4.35Å
554Q68Low76Confident148 Ų14845.9 Ų45.969%0.69224%0.24SC*.  trans-77.2111.6177-69.1-178.42.100110P552P552-Q554 VanDerWaalsContact C-N 3.27Å; P552-Q554 HydrophobicContact CB-CG 4.29Å; P552-Q554 PolarHBondContact O-N 3.38Å; P552-Q554 VanDerWaalsContact O-N 3.15Å
555C54.3Low76.5Confident24 Ų2441.9 Ų41.916%0.16222%0.22CC..  trans-110.3113.8164.8-170.80000107.9L553 S557 T558 G560 V562L553-C555 PolarHBondContact O-N 3.37Å; C555-S557 PolarHBondContact O-N 3.28Å; C555-S557 VanDerWaalsContact O-N 3.17Å; C555-S557 PolarHBondContact SG-OG 3.45Å; C555-T558 VanDerWaalsContact CB-OG1 3.29Å; C555-T558 WeakPolarHBondContact CB-OG1 3.39Å; C555-T558 PolarHBondContact O-N 3.29Å; C555-T558 VanDerWaalsContact O-N 3.13Å; C555-T558 PolarHBondContact O-OG1 3.43Å; C555-G560 PolarHBondContact O-N 3.39Å; C555-V562 HydrophobicContact CB-CG2 4.25Å
556P42Very low77.1Confident49 Ų4941.6 Ų41.632%0.31822%0.218SC..G310 helixtrans-59.6-28.1-176.2-29.839000113.3L412 T558L412-P556 HydrophobicContact CB-CB 3.76Å; L412-P556 HydrophobicContact CB-CG 3.57Å; L412-P556 HydrophobicContact CD1-CG 3.57Å; L412-P556 HydrophobicContact CG-CG 4.18Å; P556-T558 VanDerWaalsContact C-N 3.28Å; P556-T558 PolarHBondContact O-N 3.12Å
557S39.6Very low77.3Confident44 Ų4438.5 Ų38.531%0.30820%0.202SC..G310 helixtrans-72.5-18.1-179.866.90000114.6S416 C555S416-S557 WeakPolarHBondContact OG-CB 3.34Å; C555-S557 PolarHBondContact O-N 3.28Å; C555-S557 VanDerWaalsContact O-N 3.17Å; C555-S557 PolarHBondContact SG-OG 3.45Å
558T46.4Very low77.4Confident31 Ų3139.1 Ų39.119%0.1920%0.204CC..G310 helixtrans-123.522.3-170.243.90000113.4C555 P556 V561C555-T558 VanDerWaalsContact CB-OG1 3.29Å; C555-T558 WeakPolarHBondContact CB-OG1 3.39Å; C555-T558 PolarHBondContact O-N 3.29Å; C555-T558 VanDerWaalsContact O-N 3.13Å; C555-T558 PolarHBondContact O-OG1 3.43Å; P556-T558 VanDerWaalsContact C-N 3.28Å; P556-T558 PolarHBondContact O-N 3.12Å; T558-V561 WeakPolarHBondContact CB-O 3.47Å; T558-V561 WeakPolarHBondContact O-CG2 3.36Å; T558-V561 PolarHBondContact OG1-O 3.25Å
559H52.1Low77.6Confident184 Ų18438.7 Ų38.785%0.85220%0.202SC*.THydrogen-bonded Turntrans59.746.8-178.7-59.419.3000111.5
560G61.3Low77.7Confident30 Ų3038.7 Ų38.731%0.30920%0.202SC..SBendtrans79.919.6170.800000115.5C555C555-G560 PolarHBondContact O-N 3.39Å
561V77.1Confident77.9Confident14 Ų1436.8 Ų36.89%0.08519%0.193CC..  trans-136135.9175.5-60.90000112.7K502 V503 T558 P591K502-V561 HydrophobicContact CB-CB 4.38Å; K502-V561 HydrophobicContact CB-CG2 4.06Å; K502-V561 HydrophobicContact CD-CG2 4.11Å; K502-V561 HydrophobicContact CG-CG2 4.03Å; V503-V561 CarbonylContact O-C 3.57Å; V503-V561 WeakPolarHBondContact O-CA 3.29Å; T558-V561 WeakPolarHBondContact CB-O 3.47Å; T558-V561 WeakPolarHBondContact O-CG2 3.36Å; T558-V561 PolarHBondContact OG1-O 3.25Å; V561-P591 HydrophobicContact CG1-CG 4.23Å
562V84.6Confident77.9Confident1 Ų139.7 Ų39.71%0.00621%0.211CC..EExtended strand (participates in β ladder)trans-76135.5171.21650000110.5K502 V503 R527 V537 L553 C555 A564 I567K502-V562 CarbonylContact C-O 3.59Å; K502-V562 WeakPolarHBondContact CA-O 3.42Å; V503-V562 PolarHBondContact N-O 2.78Å; V503-V562 PolarHBondContact O-N 3.25Å; R527-V562 HydrophobicContact CB-CG1 4.05Å; R527-V562 HydrophobicContact CG-CG1 4.29Å; V537-V562 HydrophobicContact CG1-CG2 3.88Å; V537-V562 HydrophobicContact CG2-CG2 4.38Å; L553-V562 HydrophobicContact CB-CB 4.27Å; L553-V562 HydrophobicContact CB-CG2 3.81Å; L553-V562 HydrophobicContact CD1-CB 4.28Å; L553-V562 HydrophobicContact CD1-CG2 4.35Å; C555-V562 HydrophobicContact CB-CG2 4.25Å; V562-A564 HydrophobicContact CG1-CB 4.23Å; V562-I567 HydrophobicContact CG1-CD1 3.94Å
563R87.4Confident78.1Confident110 Ų11040.8 Ų40.842%0.41521%0.212SC..EExtended strand (participates in β ladder)trans-103.4121.3168.7-63.9-175-169.1-172.15.5109.9K500 T501 K502 R527K500-R563 HydrophobicContact CG-CB 4.27Å; T501-R563 WeakPolarHBondContact O-CA 3.34Å; K502-R563 HydrophobicContact CG-CG 3.96Å; R527-R563 PolarHBondContact NH1-O 2.82Å
564A90.1Very high78.4Confident4 Ų440.8 Ų40.83%0.03321%0.212CC..EExtended strand (participates in β ladder)trans-150.9158.4-177.500000112.5T501 R527 V562 V566 I567T501-A564 PolarHBondContact N-O 3.18Å; T501-A564 PolarHBondContact O-N 3.19Å; T501-A564 VanDerWaalsContact O-N 3.11Å; R527-A564 HydrophobicContact CB-CB 3.88Å; V562-A564 HydrophobicContact CG1-CB 4.23Å; A564-V566 WeakPolarHBondContact CB-O 3.28Å; A564-I567 HydrophobicContact CB-CD1 3.71Å; A564-I567 HydrophobicContact CB-CG1 4.27Å
565F94.4Very high79.2Confident75 Ų7536.7 Ų36.733%0.32919%0.193SC..EExtended strand (participates in β ladder)trans-92.8-31161.1-74-92.6000110.6F497 K500 G528 T529F497-F565 PolarHBondContact N-O 3.4Å; K500-F565 HydrophobicContact CB-CD2 4.12Å; K500-F565 HydrophobicContact CB-CE1 4.36Å; K500-F565 HydrophobicContact CB-CE2 3.66Å; K500-F565 HydrophobicContact CB-CZ 3.8Å; K500-F565 HydrophobicContact CD-CE2 4.22Å; K500-F565 HydrophobicContact CG-CD2 4.27Å; K500-F565 HydrophobicContact CG-CE2 4.08Å; K500-F565 VanDerWaalsContact N-CE1 3.29Å; G528-F565 PolarHBondContact O-N 2.86Å; T529-F565 HydrophobicContact CG2-CD2 4.27Å; T529-F565 WeakPolarHBondContact O-CB 3.45Å
566V95.5Very high80.6Confident2 Ų242.3 Ų42.31%0.01222%0.217CC..EExtended strand (participates in β ladder)trans-123.2130.9177.3-170.40000109.5I495 F496 R527 G528 L531 L534 A564I495-V566 CarbonylContact O-C 3.53Å; I495-V566 WeakPolarHBondContact O-CA 3.49Å; F496-V566 HydrophobicContact CD1-CB 4.44Å; F496-V566 HydrophobicContact CD1-CG1 4.18Å; F496-V566 HydrophobicContact CD1-CG2 3.54Å; F496-V566 HydrophobicContact CE1-CB 4.5Å; F496-V566 HydrophobicContact CE1-CG1 3.97Å; F496-V566 HydrophobicContact CE1-CG2 3.67Å; F496-V566 HydrophobicContact CZ-CG1 4.36Å; R527-V566 CarbonylContact C-O 3.45Å; R527-V566 VanDerWaalsContact CA-O 3.24Å; R527-V566 WeakPolarHBondContact CA-O 3.43Å; G528-V566 PolarHBondContact N-O 3.35Å; G528-V566 PolarHBondContact O-N 3.44Å; L531-V566 HydrophobicContact CD2-CG1 3.99Å; L534-V566 HydrophobicContact CD2-CB 4.25Å; L534-V566 HydrophobicContact CD2-CG1 4.07Å; A564-V566 WeakPolarHBondContact CB-O 3.28Å
567I96Very high82.5Confident0 Ų045.7 Ų45.70%023%0.232CC..EExtended strand (participates in β ladder)trans-112129.1162.1-63.9-64.6000107.4I495 F497 V503 V506 I525 R526 R527 V562 A564I495-I567 HydrophobicContact CB-CB 4.43Å; I495-I567 HydrophobicContact CD1-CB 4.38Å; I495-I567 HydrophobicContact CD1-CG2 4.2Å; I495-I567 WeakPolarHBondContact CD1-O 3.34Å; I495-I567 PolarHBondContact N-O 3.45Å; I495-I567 PolarHBondContact O-N 3.05Å; F497-I567 HydrophobicContact CE2-CG1 3.98Å; V503-I567 HydrophobicContact CG2-CD1 4.39Å; V503-I567 HydrophobicContact CG2-CG1 4.01Å; V506-I567 HydrophobicContact CG2-CG2 4.27Å; I525-I567 HydrophobicContact CG2-CG2 4.3Å; R526-I567 CarbonylContact O-C 3.57Å; R526-I567 WeakPolarHBondContact O-CA 3.38Å; R527-I567 HydrophobicContact CB-CD1 3.87Å; V562-I567 HydrophobicContact CG1-CD1 3.94Å; A564-I567 HydrophobicContact CB-CD1 3.71Å; A564-I567 HydrophobicContact CB-CG1 4.27Å
568Q96.7Very high84.5Confident14 Ų1444 Ų447%0.06522%0.221CC..EExtended strand (participates in β ladder)trans-114.9129.1173.8175.9-179.291.900109.2T492 I493 N494 I525 R526 L534 A570T492-Q568 HydrophobicContact CG2-CG 4.19Å; I493-Q568 CarbonylContact O-C 3.54Å; I493-Q568 WeakPolarHBondContact O-CA 3.46Å; N494-Q568 VanDerWaalsContact OD1-CG 3.27Å; N494-Q568 WeakPolarHBondContact OD1-CG 3.45Å; N494-Q568 PolarHBondContact OD1-NE2 2.87Å; I525-Q568 WeakPolarHBondContact CA-O 3.26Å; R526-Q568 HydrophobicContact CB-CB 4.26Å; R526-Q568 PolarHBondContact N-O 3.07Å; R526-Q568 PolarHBondContact O-N 2.8Å; L534-Q568 HydrophobicContact CD1-CB 3.96Å; L534-Q568 VanDerWaalsContact CD1-CD 3.49Å; L534-Q568 HydrophobicContact CD1-CG 4.35Å; L534-Q568 VanDerWaalsContact CD1-NE2 3.33Å; L534-Q568 HydrophobicContact CD2-CB 4.29Å; Q568-A570 HydrophobicContact CG-CB 4.47Å
569I96.6Very high86.5Confident0 Ų052.2 Ų52.20%025%0.249CC..EExtended strand (participates in β ladder)trans-99.5110.5165.8-51.2172.2000106.2T492 I493 I495 V506 I508 I525 V586T492-I569 CarbonylContact C-O 3.58Å; T492-I569 WeakPolarHBondContact CA-O 3.49Å; I493-I569 HydrophobicContact CB-CB 4.19Å; I493-I569 HydrophobicContact CD1-CD1 4.45Å; I493-I569 PolarHBondContact N-O 3.05Å; I493-I569 PolarHBondContact O-N 2.86Å; I495-I569 HydrophobicContact CD1-CD1 4.14Å; I495-I569 HydrophobicContact CD1-CG1 4.18Å; V506-I569 HydrophobicContact CG1-CD1 3.45Å; V506-I569 VanDerWaalsContact CG1-CD1 3.45Å; V506-I569 HydrophobicContact CG1-CG1 3.97Å; I508-I569 HydrophobicContact CD1-CD1 4.13Å; I508-I569 HydrophobicContact CD1-CG2 3.64Å; I508-I569 HydrophobicContact CG1-CD1 4.44Å; I525-I569 HydrophobicContact CD1-CB 4.27Å; I525-I569 HydrophobicContact CD1-CG1 3.93Å; I525-I569 HydrophobicContact CD1-CG2 4.03Å; I569-V586 HydrophobicContact CD1-CG1 3.68Å
570A95.6Very high88.4Confident0 Ų044.2 Ų44.20%021%0.213CC..EExtended strand (participates in β ladder)trans-105.3114.7177.400000109.6P490 T492 I523 S524 Q568 V572P490-A570 HydrophobicContact CB-CB 4.28Å; T492-A570 HydrophobicContact CG2-CB 4.06Å; I523-A570 CarbonylContact C-O 3.6Å; I523-A570 VanDerWaalsContact CA-O 3.3Å; I523-A570 WeakPolarHBondContact CA-O 3.4Å; S524-A570 PolarHBondContact N-O 2.83Å; S524-A570 PolarHBondContact O-N 2.99Å; Q568-A570 HydrophobicContact CG-CB 4.47Å; A570-V572 PolarHBondContact O-N 3.34Å
571I94.7Very high89.9Confident2 Ų242.8 Ų42.81%0.0120%0.198CC..EExtended strand (participates in β ladder)trans-78.6109.6173.7-59.2163.6000107.6W483 P490 H491 P520 I523 N574 S581 V583W483-I571 HydrophobicContact CH2-CD1 4.23Å; W483-I571 HydrophobicContact CZ3-CD1 3.67Å; P490-I571 WeakPolarHBondContact CA-O 3.31Å; P490-I571 WeakPolarHBondContact CB-O 3.36Å; H491-I571 HydrophobicContact CB-CB 4.41Å; H491-I571 HydrophobicContact CB-CD1 4.47Å; H491-I571 PolarHBondContact N-O 2.85Å; H491-I571 PolarHBondContact O-N 2.74Å; P520-I571 HydrophobicContact CB-CD1 4.43Å; P520-I571 HydrophobicContact CB-CG1 4.29Å; P520-I571 HydrophobicContact CB-CG2 3.88Å; P520-I571 HydrophobicContact CG-CD1 3.8Å; P520-I571 HydrophobicContact CG-CG1 4.2Å; P520-I571 HydrophobicContact CG-CG2 4.14Å; I523-I571 HydrophobicContact CG2-CG1 4.09Å; I571-N574 WeakPolarHBondContact CG2-OD1 3.27Å; I571-S581 WeakPolarHBondContact CG2-OG 3.37Å; I571-V583 HydrophobicContact CD1-CG2 3.71Å
572V91.6Very high90.8Very high61 Ų6142.8 Ų42.837%0.3720%0.197SC..EExtended strand (participates in β ladder)trans-92.2-30.1-174.2-171.90000110.8Q489 R522 A570Q489-V572 PolarHBondContact OE1-O 2.5Å; R522-V572 PolarHBondContact O-N 2.98Å; A570-V572 PolarHBondContact O-N 3.34Å
573Q91.4Very high91.2Very high63 Ų6342.9 Ų42.929%0.29420%0.197SC..EExtended strand (participates in β ladder)trans-151.4146.1179.7-167.1178.87.600110.6N521 R522 N577N521-Q573 PolarHBondContact N-O 2.79Å; N521-Q573 VanDerWaalsContact N-O 3.09Å; N521-Q573 WeakPolarHBondContact OD1-CB 3.39Å; N521-Q573 WeakPolarHBondContact OD1-CG 3.35Å; N521-Q573 PolarHBondContact OD1-O 3.47Å; R522-Q573 HydrophobicContact CB-CB 3.86Å; R522-Q573 PolarHBondContact N-O 2.78Å; R522-Q573 PolarHBondContact O-N 2.87Å; Q573-N577 PolarHBondContact NE2-OD1 2.74Å
574N90.3Very high91.6Very high0 Ų038.2 Ų38.20%018%0.18CC..EExtended strand (participates in β ladder)trans-107.5161.6171.4-67-38.3000111Q489 S517 T519 P520 I571 N577 G578 D580 S581Q489-N574 PolarHBondContact NE2-ND2 3.18Å; S517-N574 WeakPolarHBondContact O-CB 3.29Å; T519-N574 CarbonylContact O-C 3.55Å; T519-N574 WeakPolarHBondContact O-CA 3.49Å; P520-N574 WeakPolarHBondContact CA-OD1 3.46Å; I571-N574 WeakPolarHBondContact CG2-OD1 3.27Å; N574-N577 PolarHBondContact O-N 3.28Å; N574-N577 VanDerWaalsContact O-N 3.13Å; N574-G578 PolarHBondContact ND2-O 2.89Å; N574-D580 PolarHBondContact ND2-O 3.05Å; N574-S581 VanDerWaalsContact CG-OG 3.3Å; N574-S581 PolarHBondContact ND2-OG 3.46Å; N574-S581 PolarHBondContact OD1-OG 3.16Å
575H85Confident91.8Very high62 Ų6238.2 Ų38.229%0.28718%0.179SC..G310 helixtrans-55.1139.1169.5-166.264.7000110.3S517 T519 N577 G578S517-H575 CarbonylContact C-O 3.47Å; S517-H575 VanDerWaalsContact CA-O 3.29Å; S517-H575 WeakPolarHBondContact CA-O 3.15Å; T519-H575 WeakPolarHBondContact O-CB 3.39Å; T519-H575 PolarHBondContact O-N 2.96Å; H575-N577 PolarHBondContact O-N 2.91Å; H575-G578 PolarHBondContact O-N 2.82Å
576Q84.5Confident91.9Very high143 Ų14334.6 Ų34.667%0.66816%0.163SC*.G310 helixtrans51.422.8-176.2-60.5174.36.700114.8G578Q576-G578 VanDerWaalsContact C-N 3.29Å; Q576-G578 PolarHBondContact O-N 3.11Å
577N81.5Confident91.9Very high120 Ų12038.4 Ų38.464%0.64218%0.177SC*.G310 helixtrans56.635.8-178-54.1-45000114.1Q573 N574 H575Q573-N577 PolarHBondContact NE2-OD1 2.74Å; N574-N577 PolarHBondContact O-N 3.28Å; N574-N577 VanDerWaalsContact O-N 3.13Å; H575-N577 PolarHBondContact O-N 2.91Å
578G81.6Confident91.8Very high8 Ų838.4 Ų38.48%0.08218%0.177CC..  trans-57.5143.5176.100000113Q489 S517 N574 H575 Q576Q489-G578 PolarHBondContact NE2-O 2.88Å; S517-G578 VanDerWaalsContact O-CA 3.31Å; S517-G578 WeakPolarHBondContact O-CA 3.34Å; S517-G578 PolarHBondContact O-N 3.21Å; N574-G578 PolarHBondContact ND2-O 2.89Å; H575-G578 PolarHBondContact O-N 2.82Å; Q576-G578 VanDerWaalsContact C-N 3.29Å; Q576-G578 PolarHBondContact O-N 3.11Å
579R88.7Confident91.7Very high203 Ų20338 Ų3877%0.76618%0.175SC*.SBendtrans-72.8-45.1-172.4-176.6178.7176.5175.7-1.2113.5H491H491-R579 PolarHBondContact CE1-O 3.01Å
580D91.2Very high91.4Very high17 Ų1738 Ų389%0.09118%0.176CC..SBendtrans-99163.6177.2-59.8-20.1000109.5K466 S485 Y518 N574K466-D580 IonicContact NZ-OD2 3.25Å; K466-D580 PolarHBondContact NZ-OD2 2.8Å; S485-D580 WeakPolarHBondContact OG-CA 3.5Å; Y518-D580 HydrophobicContact CD1-CB 3.84Å; Y518-D580 WeakPolarHBondContact CD1-O 3.35Å; Y518-D580 HydrophobicContact CE1-CB 3.99Å; N574-D580 PolarHBondContact ND2-O 3.05Å
581S93.8Very high91Very high0 Ų040.2 Ų40.20%019%0.19CC..  trans-118.1136.7175.4-63.20000111.4Q484 S485 H491 Y518 I571 N574Q484-S581 WeakPolarHBondContact CA-O 3.33Å; S485-S581 PolarHBondContact N-O 2.8Å; S485-S581 VanDerWaalsContact N-O 3.17Å; S485-S581 PolarHBondContact OG-N 3Å; H491-S581 WeakPolarHBondContact ND1-CB 3.33Å; H491-S581 PolarHBondContact ND1-OG 3.23Å; Y518-S581 CarbonylContact O-C 3.58Å; Y518-S581 VanDerWaalsContact O-CA 3.31Å; Y518-S581 WeakPolarHBondContact O-CA 2.95Å; I571-S581 WeakPolarHBondContact CG2-OG 3.37Å; N574-S581 VanDerWaalsContact CG-OG 3.3Å; N574-S581 PolarHBondContact ND2-OG 3.46Å; N574-S581 PolarHBondContact OD1-OG 3.16Å
582H95Very high90.2Very high14 Ų1444.6 Ų44.67%0.06521%0.209CC..EExtended strand (participates in β ladder)trans-103.7124.2167.8-69.4-177.7000109.9Y482 W483 Q484 D515 Y518 P520Y482-H582 HydrophobicContact CD2-CB 4.19Å; Y482-H582 AromaticContact CD2-CD2 3.78Å; Y482-H582 AromaticContact CD2-CG 3.72Å; Y482-H582 AromaticContact CD2-ND1 3.93Å; Y482-H582 AromaticContact CE2-CD2 3.76Å; Y482-H582 AromaticContact CE2-CE1 3.52Å; Y482-H582 AromaticContact CE2-CG 3.91Å; Y482-H582 AromaticContact CE2-ND1 3.76Å; Y482-H582 AromaticContact CE2-NE2 3.52Å; Y482-H582 HydrophobicContact CG-CB 4.49Å; Y482-H582 AromaticContact CZ-CE1 3.87Å; W483-H582 VanDerWaalsContact O-CA 3.32Å; W483-H582 WeakPolarHBondContact O-CA 3.38Å; Q484-H582 PolarHBondContact NE2-NE2 2.67Å; D515-H582 HydrophobicContact CB-CB 4Å; D515-H582 IonicContact OD1-CG 2.95Å; D515-H582 IonicContact OD1-ND1 3.15Å; D515-H582 PolarHBondContact OD1-ND1 2.91Å; Y518-H582 PolarHBondContact O-N 3.42Å; P520-H582 VanDerWaalsContact CD-O 3.28Å; P520-H582 WeakPolarHBondContact CD-O 3.34Å
583V94.5Very high88.7Confident2 Ų245.3 Ų45.31%0.01223%0.229CC..EExtended strand (participates in β ladder)trans-127.1116.4170.7-174.40000108.6L474 Y482 W483 I508 P520 I571 V586L474-V583 HydrophobicContact CD1-CB 3.72Å; L474-V583 HydrophobicContact CD1-CG1 3.53Å; Y482-V583 WeakPolarHBondContact CA-O 3.5Å; W483-V583 HydrophobicContact CE3-CB 3.97Å; W483-V583 HydrophobicContact CE3-CG2 3.76Å; W483-V583 HydrophobicContact CZ3-CG2 4.02Å; W483-V583 PolarHBondContact N-O 3.24Å; W483-V583 PolarHBondContact O-N 2.81Å; W483-V583 VanDerWaalsContact O-N 3.07Å; I508-V583 HydrophobicContact CG2-CG1 3.58Å; P520-V583 HydrophobicContact CG-CG2 3.99Å; I571-V583 HydrophobicContact CD1-CG2 3.71Å; V583-V586 HydrophobicContact CG1-CG2 3.64Å
584R94.7Very high86.3Confident13 Ų1351.4 Ų51.45%0.04925%0.254CS..  trans-76.6-46.2-173.9-72.6171.7-177.7-86.8-8112.2F479 T481 F509 D515F479-R584 WeakPolarHBondContact O-CD 3.38Å; F479-R584 PolarHBondContact O-NH1 3.33Å; T481-R584 WeakPolarHBondContact O-CA 3.45Å; F509-R584 HydrophobicContact CD1-CB 3.92Å; D515-R584 IonicContact OD1-CZ 2.66Å; D515-R584 IonicContact OD1-NE 2.79Å; D515-R584 IonicContact OD1-NH2 2.8Å; D515-R584 PolarHBondContact OD1-NH2 3.2Å; D515-R584 IonicContact OD2-CZ 3.13Å; D515-R584 IonicContact OD2-NE 2.94Å; D515-R584 PolarHBondContact OD2-NE 3Å; D515-R584 IonicContact OD2-NH2 2.69Å; D515-R584 PolarHBondContact OD2-NH2 2.96Å
585Q95.5Very high83.4Confident3 Ų356.2 Ų56.21%0.01429%0.288CS..EExtended strand (participates in β ladder)trans-147.2146.4178.5-68.2-66-52.200111.9Q473 L474 D476 G477 K478 F479 F509 W548Q473-Q585 PolarHBondContact O-NE2 2.79Å; L474-Q585 WeakPolarHBondContact O-CA 3.24Å; L474-Q585 PolarHBondContact O-OE1 3.13Å; D476-Q585 PolarHBondContact OD1-NE2 3.39Å; G477-Q585 VanDerWaalsContact CA-OE1 3.28Å; K478-Q585 PolarHBondContact O-NE2 3.36Å; F479-Q585 HydrophobicContact CD1-CG 4.17Å; F479-Q585 HydrophobicContact CE1-CG 4.23Å; F509-Q585 HydrophobicContact CB-CB 3.96Å; F509-Q585 PolarHBondContact N-O 3.45Å; W548-Q585 HydrophobicContact CH2-CB 3.59Å; W548-Q585 HydrophobicContact CZ2-CB 4.24Å; W548-Q585 HydrophobicContact CZ3-CB 4.25Å
586V96Very high80.8Confident0 Ų064.4 Ų64.40%032%0.316CS..EExtended strand (participates in β ladder)trans-130.6132.9168.5-178.70000110.6W460 L474 R475 I493 C507 I508 I569 V583 I588W460-V586 HydrophobicContact CH2-CB 4.21Å; W460-V586 HydrophobicContact CH2-CG1 3.74Å; W460-V586 HydrophobicContact CZ3-CB 4.1Å; W460-V586 HydrophobicContact CZ3-CG1 3.81Å; L474-V586 HydrophobicContact CD1-CB 4.39Å; L474-V586 HydrophobicContact CD1-CG2 3.65Å; L474-V586 HydrophobicContact CD2-CB 4.29Å; L474-V586 HydrophobicContact CD2-CG2 4.11Å; L474-V586 HydrophobicContact CG-CB 4.15Å; L474-V586 HydrophobicContact CG-CG2 3.93Å; L474-V586 PolarHBondContact O-N 2.95Å; L474-V586 VanDerWaalsContact O-N 3.1Å; R475-V586 WeakPolarHBondContact CD-O 3.44Å; R475-V586 PolarHBondContact NH1-O 2.82Å; I493-V586 HydrophobicContact CD1-CG2 3.97Å; C507-V586 CarbonylContact O-C 3.57Å; C507-V586 WeakPolarHBondContact O-CA 3.4Å; I508-V586 HydrophobicContact CG1-CG2 4.28Å; I508-V586 HydrophobicContact CG2-CG2 4.31Å; I569-V586 HydrophobicContact CD1-CG1 3.68Å; V583-V586 HydrophobicContact CG1-CG2 3.64Å; V586-I588 HydrophobicContact CG1-CG1 4.49Å
587R95.2Very high78.1Confident82 Ų8264.1 Ų64.131%0.30932%0.319SS..EExtended strand (participates in β ladder)trans-126.9143.4173.8-66.4-172.6-177.6-170.9-0.1111.2E453 C507 W548 F589E453-R587 HydrophobicContact CG-CB 4.38Å; C507-R587 HydrophobicContact CB-CB 4.33Å; C507-R587 PolarHBondContact N-O 3.38Å; C507-R587 PolarHBondContact O-N 3.02Å; W548-R587 HydrophobicContact CH2-CG 3.93Å; W548-R587 HydrophobicContact CZ3-CB 4.45Å; W548-R587 HydrophobicContact CZ3-CG 4.26Å; R587-F589 HydrophobicContact CB-CE2 3.75Å; R587-F589 HydrophobicContact CB-CZ 4.2Å
588I94.2Very high75.5Confident0 Ų067.7 Ų67.70%033%0.329CS..EExtended strand (participates in β ladder)trans-126.2130.1-179.7-61.1177.8000108.4E453 I454 W460 I495 F497 V503 H505 V506 V586E453-I588 CarbonylContact C-O 3.54Å; E453-I588 WeakPolarHBondContact CA-O 3.35Å; E453-I588 PolarHBondContact OE1-N 3.36Å; I454-I588 HydrophobicContact CD1-CG2 4.02Å; I454-I588 HydrophobicContact CG1-CB 4.36Å; I454-I588 HydrophobicContact CG1-CG2 3.84Å; I454-I588 WeakPolarHBondContact CG1-O 2.97Å; I454-I588 PolarHBondContact N-O 3.13Å; W460-I588 HydrophobicContact CH2-CD1 3.47Å; W460-I588 VanDerWaalsContact CH2-CD1 3.47Å; W460-I588 HydrophobicContact CH2-CG1 3.88Å; W460-I588 HydrophobicContact CZ2-CD1 3.79Å; W460-I588 HydrophobicContact CZ2-CG1 4.27Å; W460-I588 HydrophobicContact CZ3-CD1 4.3Å; I495-I588 HydrophobicContact CB-CD1 4.01Å; I495-I588 HydrophobicContact CD1-CD1 3.39Å; I495-I588 HydrophobicContact CG1-CD1 3.49Å; I495-I588 VanDerWaalsContact CG1-CD1 3.49Å; I495-I588 HydrophobicContact CG2-CD1 3.85Å; F497-I588 HydrophobicContact CZ-CG2 4.4Å; V503-I588 HydrophobicContact CG1-CG2 3.38Å; H505-I588 WeakPolarHBondContact O-CA 3.14Å; V506-I588 HydrophobicContact CG2-CG1 4.38Å; V586-I588 HydrophobicContact CG1-CG1 4.49Å
589F93.6Very high73.1Confident4 Ų473.4 Ų73.42%0.01836%0.362CS..EExtended strand (participates in β ladder)trans-114.7136.6-176.6-65.2-91.8000110.9L441 L445 K452 E453 S504 H505 C507 R587L441-F589 HydrophobicContact CD1-CE2 4.32Å; L441-F589 HydrophobicContact CD1-CZ 4.11Å; L445-F589 HydrophobicContact CB-CD1 4.32Å; L445-F589 HydrophobicContact CB-CE1 4.12Å; L445-F589 HydrophobicContact CB-CE2 4.46Å; L445-F589 HydrophobicContact CB-CZ 4.19Å; L445-F589 HydrophobicContact CD1-CD2 4.49Å; L445-F589 HydrophobicContact CD2-CB 4.31Å; L445-F589 HydrophobicContact CD2-CD1 4.48Å; L445-F589 HydrophobicContact CD2-CD2 4.43Å; L445-F589 HydrophobicContact CD2-CG 4.16Å; L445-F589 WeakPolarHBondContact O-CD1 3.38Å; L445-F589 WeakPolarHBondContact O-CE1 3.35Å; K452-F589 CarbonylContact O-C 3.59Å; K452-F589 VanDerWaalsContact O-CA 3.28Å; K452-F589 WeakPolarHBondContact O-CA 3.37Å; E453-F589 HydrophobicContact CB-CD1 4.36Å; E453-F589 HydrophobicContact CB-CE1 4.15Å; E453-F589 HydrophobicContact CG-CE1 4.18Å; E453-F589 HydrophobicContact CG-CZ 4.33Å; S504-F589 WeakPolarHBondContact CA-O 3.45Å; S504-F589 PolarHBondContact N-O 2.85Å; S504-F589 VanDerWaalsContact OG-C 3.28Å; S504-F589 PolarHBondContact OG-O 2.84Å; H505-F589 HydrophobicContact CB-CB 4.23Å; H505-F589 HydrophobicContact CB-CD2 4.39Å; H505-F589 PolarHBondContact N-O 2.78Å; H505-F589 VanDerWaalsContact N-O 3.17Å; H505-F589 PolarHBondContact O-N 3.31Å; C507-F589 HydrophobicContact CB-CE2 4.28Å; R587-F589 HydrophobicContact CB-CE2 3.75Å; R587-F589 HydrophobicContact CB-CZ 4.2Å
590G90.8Very high70.4Confident1 Ų170.8 Ų70.81%0.0136%0.364CS..EExtended strand (participates in β ladder)trans-116.9168.8166.900000111.1Y451 K452 K502Y451-G590 CarbonylContact C-O 3.58Å; Y451-G590 VanDerWaalsContact CA-O 3.28Å; Y451-G590 WeakPolarHBondContact CA-O 3.4Å; K452-G590 PolarHBondContact N-O 2.88Å; K452-G590 PolarHBondContact O-N 2.78Å; K502-G590 WeakPolarHBondContact O-CA 3.4Å
591P87.4Confident67.3Low46 Ų4673.3 Ų73.330%0.29939%0.393SS..EExtended strand (participates in β ladder)trans-69.714017628.6-33.5000112.3K450 K502 V561K450-P591 CarbonylContact O-C 3.48Å; K450-P591 VanDerWaalsContact O-CA 3.28Å; K450-P591 WeakPolarHBondContact O-CA 3.24Å; K502-P591 HydrophobicContact CB-CG 3.97Å; K502-P591 HydrophobicContact CD-CG 4.14Å; K502-P591 WeakPolarHBondContact O-CD 3.23Å; V561-P591 HydrophobicContact CG1-CG 4.23Å
592K78.8Confident64.3Low94 Ų9480.2 Ų80.241%0.40944%0.435SS..  trans-83.9120.8165.4-88.1176.8-175.3166.90108.4S448 D449 K450 Y451 K452S448-K592 PolarHBondContact O-NZ 2.96Å; D449-K592 WeakPolarHBondContact O-CB 3.47Å; K450-K592 PolarHBondContact O-N 3.12Å; Y451-K592 WeakPolarHBondContact O-CD 3.32Å; Y451-K592 WeakPolarHBondContact O-CE 3.34Å; Y451-K592 WeakPolarHBondContact O-CG 3.39Å; Y451-K592 PolarHBondContact O-NZ 2.69Å; K452-K592 HydrophobicContact CB-CD 4.32Å; K452-K592 HydrophobicContact CB-CG 3.62Å; K452-K592 HydrophobicContact CG-CG 3.95Å
593G59.6Low61Low76 Ų7688.5 Ų88.578%0.78447%0.474SS*.  trans157.7132.117600000114.7
594K41.3Very low57.9Low192 Ų192100.1 Ų100.184%0.83553%0.534SS*.  trans-52.8146.2-169.2-69.7174.3176.7174.70113.5W596K594-W596 PolarHBondContact O-N 3.12Å; K594-W596 VanDerWaalsContact O-N 3.15Å
595S29.5Very low56.1Low101 Ų101104.5 Ų104.571%0.70656%0.559SS**  trans-41.8123.2155.752.30000108.4N597S595-N597 PolarHBondContact O-N 2.83Å
596W29.8Very low54Low234 Ų234109.8 Ų109.889%0.88659%0.587SS**  trans-53.9111.3171.3-73.679.9000107.2K594 K598K594-W596 PolarHBondContact O-N 3.12Å; K594-W596 VanDerWaalsContact O-N 3.15Å; W596-K598 PolarHBondContact O-N 2.76Å
597N28.4Very low51.7Low136 Ų136115.9 Ų115.973%0.72762%0.62SS**  trans-54.1134.6165.9-82.9-22.7000106.8S595 V599S595-N597 PolarHBondContact O-N 2.83Å; N597-V599 PolarHBondContact O-N 3.36Å
598K25.7Very low49.1Very low195 Ų195117.9 Ų117.985%0.84864%0.638SS**  trans-34.6109.2172.4-77176.3172.3178.40109.7W596 N600W596-K598 PolarHBondContact O-N 2.76Å; K598-N600 PolarHBondContact O-N 2.59Å
599V31.8Very low46.3Very low128 Ų128125.3 Ų125.378%0.77668%0.678SS**  trans-69.3116.3155.4177.20000104.5N597 G601N597-V599 PolarHBondContact O-N 3.36Å; V599-G601 PolarHBondContact O-N 3.1Å
600N31.2Very low43.2Very low149 Ų149133.3 Ų133.380%0.79772%0.722SS**SBendtrans-48.6133.2171-73.5-35000110.3K598K598-N600 PolarHBondContact O-N 2.59Å
601G27.5Very low39.8Very low69 Ų69142.8 Ų142.871%0.71177%0.773SS**  trans75.698.6158.900000114.7V599V599-G601 PolarHBondContact O-N 3.1Å
602V29.9Very low36.1Very low145 Ų145150.2 Ų150.288%0.87981%0.81SS**  175.9120.6114.2159.60000106.7
603Q25.3Very low32.5Very low188 Ų188154.9 Ų154.988%0.87984%0.843SS**  trans-74.9117.9166.3-85.5174-47.100108.9
604L30.6Very low30.1Very low246 Ų246162.1 Ų162.1100%1.28885%0.848SS**  -169.40122-97166.6000109.4

Retrieved 604 of 604 residues in 268.2 ms (Link to these results)