A0A077Z763_TRITR Loading...

PRKCA-binding protein

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

AlphaFold DB , UniProt , Accession A0A077Z763, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 448 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	28.9	Very low	26.1	Very low	241 Å²	241	159.8 Å²	159.8	100%	1.187	84%	0.836	S	S	*	*				0	58.5	0	-75.7	179.1	160.1	0	0	109.9	C3	M1-C3 PolarHBondContact O-N 2.72Å
2	T	23.9	Very low	26.4	Very low	153 Å²	153	160.3 Å²	160.3	94%	0.939	83%	0.827	S	S	*	*			trans	-97.4	87.5	175.3	31	0	0	0	0	107.7
3	C	25.9	Very low	26.9	Very low	126 Å²	126	158 Å²	158	85%	0.851	80%	0.802	S	S	*	*			trans	-139.5	133.7	169	-160.7	0	0	0	0	107.4	M1	M1-C3 PolarHBondContact O-N 2.72Å
4	A	27.2	Very low	26.8	Very low	96 Å²	96	156 Å²	156	79%	0.793	79%	0.788	S	S	*	*	S	Bend	trans	79.6	74.8	-174.2	0	0	0	0	0	116.5
5	R	24.4	Very low	26.9	Very low	254 Å²	254	157.2 Å²	157.2	96%	0.958	79%	0.79	S	S	*	*			trans	-143.8	17.2	158.6	-115.2	-174.5	-172.6	-169	0.6	116.8
6	E	25.6	Very low	27	Very low	180 Å²	180	153.4 Å²	153.4	84%	0.841	77%	0.773	S	S	*	*	S	Bend	trans	-131.8	36.3	-172.9	-71.5	-173.1	162.2	0	0	116.1
7	L	25.7	Very low	27.3	Very low	165 Å²	165	157 Å²	157	86%	0.864	78%	0.782	S	S	*	*	S	Bend	trans	-129.3	17.4	-179	-92	166.5	0	0	0	117.8
8	E	24.2	Very low	28.2	Very low	195 Å²	195	151.9 Å²	151.9	91%	0.911	75%	0.752	S	S	*	*			trans	-119.3	14.8	178	-74.5	-176.2	165.6	0	0	115.1	D10	E8-D10 PolarHBondContact O-N 3.17Å
9	T	24.1	Very low	28.8	Very low	118 Å²	118	146.3 Å²	146.3	72%	0.724	72%	0.722	S	S	*	*			trans	-75.5	121.7	168.8	41.2	0	0	0	0	111
10	D	25.5	Very low	29.2	Very low	118 Å²	118	144 Å²	144	63%	0.631	73%	0.727	S	S	*	*			trans	82.8	86.4	152.8	-52.3	-28.6	0	0	0	118.2	E8 F12	E8-D10 PolarHBondContact O-N 3.17Å; D10-F12 HydrophobicContact CB-CD2 4.23Å
11	F	32.2	Very low	29.7	Very low	112 Å²	112	141.1 Å²	141.1	49%	0.491	72%	0.721	S	S	.	*			trans	-97.8	80.3	145.3	-74.5	-83.4	0	0	0	109.1	F331 R335	F11-F331 HydrophobicContact CZ-CE2 4.5Å; F11-R335 VanDerWaalsContact CZ-NH1 3.27Å
12	F	29.3	Very low	30.1	Very low	166 Å²	166	130.3 Å²	130.3	73%	0.728	67%	0.668	S	S	*	*			trans	-95.5	128	157.3	-73.4	-83	0	0	0	108.2	D10 E14	D10-F12 HydrophobicContact CB-CD2 4.23Å; F12-E14 PolarHBondContact O-N 3.49Å
13	Y	32.5	Very low	31	Very low	130 Å²	130	128.3 Å²	128.3	51%	0.51	65%	0.651	S	S	.	*			trans	-67.2	106.2	156.4	-168.7	-81.7	0	0	0	104.7	E15 Y19	Y13-E15 PolarHBondContact O-N 3.42Å; Y13-Y19 PolarHBondContact OH-OH 3.12Å
14	E	26.6	Very low	31.9	Very low	130 Å²	130	126.8 Å²	126.8	61%	0.607	64%	0.639	S	S	*	*			trans	-65.3	120.7	168.8	-149.5	156.2	-163.6	0	0	105.9	F12 D16	F12-E14 PolarHBondContact O-N 3.49Å; E14-D16 PolarHBondContact O-N 3.42Å
15	E	27.6	Very low	32.5	Very low	174 Å²	174	127 Å²	127	81%	0.813	62%	0.622	S	S	*	*			trans	-66.7	69.1	177.7	-77.1	-178	158.6	0	0	109.9	Y13	Y13-E15 PolarHBondContact O-N 3.42Å
16	D	27.8	Very low	33.3	Very low	96 Å²	96	117 Å²	117	51%	0.513	59%	0.588	S	S	.	*			trans	-85.9	132.9	-176.2	-88.7	-23.3	0	0	0	112.9	E14 W18	E14-D16 PolarHBondContact O-N 3.42Å; D16-W18 PolarHBondContact O-N 2.89Å; D16-W18 VanDerWaalsContact O-N 3.12Å
17	K	32.8	Very low	34.1	Very low	215 Å²	215	114.9 Å²	114.9	94%	0.935	58%	0.578	S	S	*	*	S	Bend	trans	-77.7	73.2	-166.5	-64.6	172.7	174.7	172.8	0	113.9
18	W	42.7	Very low	34.7	Very low	65 Å²	65	116.4 Å²	116.4	25%	0.246	57%	0.572	C	S	.	*			trans	-124.8	0.8	174.6	67.4	-92.3	0	0	0	116.1	D16 A20 L22 S163	D16-W18 PolarHBondContact O-N 2.89Å; D16-W18 VanDerWaalsContact O-N 3.12Å; W18-A20 VanDerWaalsContact C-N 3.29Å; W18-A20 PolarHBondContact O-N 2.86Å; W18-L22 HydrophobicContact CE3-CD1 4.09Å; W18-L22 HydrophobicContact CZ3-CD1 3.58Å; W18-S163 VanDerWaalsContact CZ3-CB 3.48Å
19	Y	40.7	Very low	35.2	Very low	46 Å²	46	111 Å²	111	18%	0.18	55%	0.549	C	S	.	.	G	3₁₀ helix	trans	-71.6	-13.1	-173.8	-78.8	-96.2	0	0	0	115.7	Y13 S21 L288 K291	Y13-Y19 PolarHBondContact OH-OH 3.12Å; Y19-S21 VanDerWaalsContact C-N 3.29Å; Y19-S21 PolarHBondContact O-N 3.14Å; Y19-L288 HydrophobicContact CE1-CD1 4.24Å; Y19-K291 HydrophobicContact CE1-CD 4.23Å; Y19-K291 HydrophobicContact CE2-CD 4.15Å
20	A	36.8	Very low	35.7	Very low	99 Å²	99	109.6 Å²	109.6	82%	0.818	54%	0.544	S	S	*	.	G	3₁₀ helix	trans	-70	-19.9	-175.2	0	0	0	0	0	114.4	W18	W18-A20 VanDerWaalsContact C-N 3.29Å; W18-A20 PolarHBondContact O-N 2.86Å
21	S	39.6	Very low	36.3	Very low	85 Å²	85	110.3 Å²	110.3	59%	0.594	55%	0.547	S	S	*	.	G	3₁₀ helix	trans	-96	-10.6	-174.9	59.9	0	0	0	0	115.4	Y19	Y19-S21 VanDerWaalsContact C-N 3.29Å; Y19-S21 PolarHBondContact O-N 3.14Å
22	L	38.1	Very low	36.3	Very low	13 Å²	13	110 Å²	110	7%	0.068	56%	0.556	C	S	.	*	T	Hydrogen-bonded Turn	trans	-120	-2.2	-168.5	-80.7	167.3	0	0	0	116.6	W18 F25 I26 G161 S163	W18-L22 HydrophobicContact CE3-CD1 4.09Å; W18-L22 HydrophobicContact CZ3-CD1 3.58Å; L22-F25 HydrophobicContact CD2-CB 4.26Å; L22-F25 PolarHBondContact O-N 3.19Å; L22-F25 VanDerWaalsContact O-N 3.13Å; L22-I26 HydrophobicContact CB-CD1 4.49Å; L22-I26 PolarHBondContact O-N 2.75Å; L22-G161 WeakPolarHBondContact CD2-O 3.2Å; L22-S163 VanDerWaalsContact CD1-OG 3.32Å; L22-S163 WeakPolarHBondContact CD1-OG 3.39Å
23	L	41.8	Very low	36.9	Very low	111 Å²	111	106.3 Å²	106.3	58%	0.581	55%	0.551	S	S	*	*	H	α-helix	trans	-46.3	-42.5	170.5	-79.6	164.1	0	0	0	113.2	F25 E27	L23-F25 VanDerWaalsContact C-N 3.35Å; L23-F25 PolarHBondContact O-N 3.32Å; L23-E27 WeakPolarHBondContact O-CG 3.33Å; L23-E27 PolarHBondContact O-N 3.34Å
24	P	45.1	Very low	36.9	Very low	95 Å²	95	110.7 Å²	110.7	62%	0.617	57%	0.568	S	S	*	*	H	α-helix	trans	-68.3	-28.8	-177	-20.3	33.1	0	0	0	114.6
25	F	38.6	Very low	37.2	Very low	99 Å²	99	108.1 Å²	108.1	43%	0.434	58%	0.577	S	S	.	*	H	α-helix	trans	-88.3	-30.8	-176.5	-169.3	-103.4	0	0	0	112.4	L22 L23 W28 L29	L22-F25 HydrophobicContact CD2-CB 4.26Å; L22-F25 PolarHBondContact O-N 3.19Å; L22-F25 VanDerWaalsContact O-N 3.13Å; L23-F25 VanDerWaalsContact C-N 3.35Å; L23-F25 PolarHBondContact O-N 3.32Å; F25-W28 HydrophobicContact CE2-CE3 4.3Å; F25-L29 HydrophobicContact CE1-CD1 4.19Å; F25-L29 HydrophobicContact CZ-CD1 4.49Å
26	I	42	Very low	37.8	Very low	46 Å²	46	104.7 Å²	104.7	24%	0.236	56%	0.559	C	S	.	*	H	α-helix	trans	-75.5	-37.6	177.2	-63.5	175.1	0	0	0	110.7	L22 W28 L29 E292	L22-I26 HydrophobicContact CB-CD1 4.49Å; L22-I26 PolarHBondContact O-N 2.75Å; I26-W28 VanDerWaalsContact C-N 3.26Å; I26-W28 PolarHBondContact O-N 3.23Å; I26-L29 PolarHBondContact O-N 3.18Å; I26-E292 WeakPolarHBondContact CG2-OE1 2.9Å
27	E	41.5	Very low	38.8	Very low	134 Å²	134	104.5 Å²	104.5	63%	0.626	57%	0.566	S	S	*	*	H	α-helix	trans	-59.7	-36.7	173.3	-79	-179.5	163.4	0	0	112.2	L23 L29 S30	L23-E27 WeakPolarHBondContact O-CG 3.33Å; L23-E27 PolarHBondContact O-N 3.34Å; E27-L29 VanDerWaalsContact C-N 3.29Å; E27-L29 PolarHBondContact O-N 3.49Å; E27-S30 PolarHBondContact O-N 3.17Å; E27-S30 PolarHBondContact O-OG 3.17Å
28	W	39.1	Very low	39.9	Very low	197 Å²	197	97.7 Å²	97.7	75%	0.746	56%	0.556	S	S	*	*	H	α-helix	trans	-65.4	-26.7	-178.2	-173.2	62.2	0	0	0	114.4	F25 I26	F25-W28 HydrophobicContact CE2-CE3 4.3Å; I26-W28 VanDerWaalsContact C-N 3.26Å; I26-W28 PolarHBondContact O-N 3.23Å
29	L	34.7	Very low	40.9	Very low	83 Å²	83	97.4 Å²	97.4	44%	0.435	56%	0.558	S	S	.	*	T	Hydrogen-bonded Turn	trans	-96.8	-0.1	180	-80.9	161.9	0	0	0	113.8	F25 I26 E27 L31	F25-L29 HydrophobicContact CE1-CD1 4.19Å; F25-L29 HydrophobicContact CZ-CD1 4.49Å; I26-L29 PolarHBondContact O-N 3.18Å; E27-L29 VanDerWaalsContact C-N 3.29Å; E27-L29 PolarHBondContact O-N 3.49Å; L29-L31 PolarHBondContact O-N 3.36Å; L29-L31 VanDerWaalsContact O-N 3.15Å
30	S	34.7	Very low	42.7	Very low	88 Å²	88	99.5 Å²	99.5	62%	0.615	58%	0.576	S	S	*	*			trans	-72.2	107.3	-179.8	66.9	0	0	0	0	111.4	E27	E27-S30 PolarHBondContact O-N 3.17Å; E27-S30 PolarHBondContact O-OG 3.17Å
31	L	37.5	Very low	44.9	Very low	133 Å²	133	97.8 Å²	97.8	70%	0.696	56%	0.556	S	S	*	*	P	Polyproline II helix	trans	-87.8	142.5	169.6	-73.3	172.1	0	0	0	110.2	L29 S33	L29-L31 PolarHBondContact O-N 3.36Å; L29-L31 VanDerWaalsContact O-N 3.15Å; L31-S33 PolarHBondContact O-N 3.45Å
32	P	33.6	Very low	47.3	Very low	104 Å²	104	96.1 Å²	96.1	68%	0.675	54%	0.544	S	S	*	.	P	Polyproline II helix	trans	-61.7	130	174.8	-19.9	30.5	0	0	0	112.1	Y34	P32-Y34 PolarHBondContact O-N 3.17Å
33	S	41	Very low	49.9	Very low	90 Å²	90	100.3 Å²	100.3	63%	0.629	57%	0.574	S	S	*	*	P	Polyproline II helix	trans	-67	120.4	173.9	-173.1	0	0	0	0	110.3	L31	L31-S33 PolarHBondContact O-N 3.45Å
34	Y	32.8	Very low	52.4	Low	222 Å²	222	96.8 Å²	96.8	87%	0.871	56%	0.561	S	S	*	*	P	Polyproline II helix	trans	-97.2	123.3	177.8	-97.6	-93.3	0	0	0	111.5	P32	P32-Y34 PolarHBondContact O-N 3.17Å
35	G	32.9	Very low	54.8	Low	76 Å²	76	95.7 Å²	95.7	78%	0.784	56%	0.555	S	S	*	*			trans	48.3	93.7	148.8	0	0	0	0	0	118.9
36	F	41.1	Very low	57.5	Low	101 Å²	101	91.4 Å²	91.4	44%	0.443	54%	0.538	S	S	.	.			trans	-81.5	128	177.4	-164.7	-100.1	0	0	0	113.1	Q133 Y315 L319	F36-Q133 HydrophobicContact CE2-CB 4.38Å; F36-Q133 HydrophobicContact CE2-CG 4.39Å; F36-Y315 AromaticContact CD1-CD1 3.77Å; F36-Y315 HydrophobicContact CD1-CD1 3.77Å; F36-Y315 AromaticContact CD1-CE1 3.68Å; F36-Y315 HydrophobicContact CD1-CE1 3.68Å; F36-Y315 HydrophobicContact CD1-CE2 4.48Å; F36-Y315 HydrophobicContact CD1-CG 4.32Å; F36-Y315 AromaticContact CD2-CD1 3.99Å; F36-Y315 HydrophobicContact CD2-CD1 3.99Å; F36-Y315 AromaticContact CD2-CE1 3.56Å; F36-Y315 HydrophobicContact CD2-CE1 3.56Å; F36-Y315 AromaticContact CE1-CD1 3.73Å; F36-Y315 HydrophobicContact CE1-CD1 3.73Å; F36-Y315 HydrophobicContact CE1-CD2 4.19Å; F36-Y315 AromaticContact CE1-CE1 3.2Å; F36-Y315 HydrophobicContact CE1-CE1 3.2Å; F36-Y315 AromaticContact CE1-CE2 3.66Å; F36-Y315 HydrophobicContact CE1-CE2 3.66Å; F36-Y315 HydrophobicContact CE1-CG 4.24Å; F36-Y315 AromaticContact CE1-CZ 3.16Å; F36-Y315 WeakPolarHBondContact CE1-OH 3.17Å; F36-Y315 AromaticContact CE2-CD1 3.99Å; F36-Y315 HydrophobicContact CE2-CD1 3.99Å; F36-Y315 AromaticContact CE2-CE1 3.1Å; F36-Y315 HydrophobicContact CE2-CE1 3.1Å; F36-Y315 AromaticContact CE2-CZ 3.62Å; F36-Y315 AromaticContact CG-CD1 3.96Å; F36-Y315 HydrophobicContact CG-CD1 3.96Å; F36-Y315 AromaticContact CG-CE1 3.88Å; F36-Y315 HydrophobicContact CG-CE1 3.88Å; F36-Y315 AromaticContact CZ-CD1 3.93Å; F36-Y315 HydrophobicContact CZ-CD1 3.93Å; F36-Y315 AromaticContact CZ-CE1 2.97Å; F36-Y315 HydrophobicContact CZ-CE1 2.97Å; F36-Y315 AromaticContact CZ-CE2 3.92Å; F36-Y315 HydrophobicContact CZ-CE2 3.92Å; F36-Y315 AromaticContact CZ-CZ 2.97Å; F36-Y315 WeakPolarHBondContact CZ-OH 3.47Å; F36-L319 HydrophobicContact CE2-CD2 4.31Å
37	S	48.1	Very low	60	Low	93 Å²	93	92.8 Å²	92.8	65%	0.65	55%	0.548	S	S	*	.			trans	-88.6	134.8	170.2	-74.7	0	0	0	0	110.7
38	G	55.8	Low	62.5	Low	71 Å²	71	86.4 Å²	86.4	73%	0.732	52%	0.519	S	S	*	.			trans	-40.4	143.7	-160.4	0	0	0	0	0	119.3
39	M	64.3	Low	65.1	Low	60 Å²	60	82.5 Å²	82.5	30%	0.296	51%	0.509	S	S	.	.			trans	-73.3	130.8	174.8	-175.9	179.3	-133.4	0	0	110.6	T41 L127 Y315	M39-T41 HydrophobicContact CG-CG2 3.78Å; M39-T41 HydrophobicContact SD-CG2 3.94Å; M39-L127 HydrophobicContact CE-CB 4.41Å; M39-L127 HydrophobicContact CE-CD1 3.21Å; M39-L127 HydrophobicContact CE-CD2 3.72Å; M39-L127 HydrophobicContact CE-CG 3.94Å; M39-L127 HydrophobicContact CG-CD1 3.72Å; M39-L127 HydrophobicContact SD-CD1 4.14Å; M39-Y315 HydrophobicContact CB-CD2 3.94Å; M39-Y315 HydrophobicContact CB-CE2 3.5Å; M39-Y315 VanDerWaalsContact CB-CE2 3.5Å; M39-Y315 HydrophobicContact CE-CD2 3.26Å; M39-Y315 HydrophobicContact CE-CE2 3.27Å; M39-Y315 HydrophobicContact CE-CG 4.48Å; M39-Y315 HydrophobicContact CG-CD2 3.93Å; M39-Y315 HydrophobicContact CG-CE2 3.4Å; M39-Y315 VanDerWaalsContact CG-CE2 3.4Å; M39-Y315 HydrophobicContact SD-CD2 3.37Å; M39-Y315 WeakPolarHBondContact SD-CD2 3.38Å; M39-Y315 HydrophobicContact SD-CE2 3.46Å; M39-Y315 WeakPolarHBondContact SD-CE2 3.43Å
40	T	76.8	Confident	67.7	Low	89 Å²	89	79.9 Å²	79.9	55%	0.546	49%	0.493	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	124.4	166.9	49.9	0	0	0	0	109.4	H128	T40-H128 WeakPolarHBondContact O-CB 3.47Å; T40-H128 PolarHBondContact O-CD2 3.06Å; T40-H128 PolarHBondContact O-N 3.09Å; T40-H128 WeakPolarHBondContact OG1-CB 3.3Å
41	T	84	Confident	70.1	Confident	64 Å²	64	78.6 Å²	78.6	39%	0.393	48%	0.48	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.7	149.9	172.8	62	0	0	0	0	111.3	M39 K126	M39-T41 HydrophobicContact CG-CG2 3.78Å; M39-T41 HydrophobicContact SD-CG2 3.94Å; T41-K126 WeakPolarHBondContact CA-O 3.42Å; T41-K126 VanDerWaalsContact CB-O 3.29Å; T41-K126 WeakPolarHBondContact CB-O 3.44Å
42	S	90	Very high	72.2	Confident	50 Å²	50	80.9 Å²	80.9	35%	0.35	49%	0.493	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.3	128.5	170.7	66.8	0	0	0	0	109.7	K126 H128	S42-K126 PolarHBondContact N-O 2.74Å; S42-K126 WeakPolarHBondContact O-CB 3.39Å; S42-K126 PolarHBondContact O-N 2.95Å; S42-K126 WeakPolarHBondContact OG-CB 3.48Å; S42-H128 PolarHBondContact OG-NE2 3.29Å
43	S	92.8	Very high	74.6	Confident	101 Å²	101	78.5 Å²	78.5	71%	0.706	49%	0.487	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-75.9	132.6	175.4	-56.8	0	0	0	0	110.9	Y124 N125	S43-Y124 WeakPolarHBondContact CA-O 3.17Å; S43-N125 PolarHBondContact OG-OD1 3.41Å
44	A	94.6	Very high	76.6	Confident	37 Å²	37	77.4 Å²	77.4	31%	0.306	47%	0.474	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.7	168.1	176.7	0	0	0	0	0	110.3	D123 Y124	A44-D123 WeakPolarHBondContact O-CA 3.46Å; A44-Y124 HydrophobicContact CB-CE1 3.9Å; A44-Y124 HydrophobicContact CB-CE2 3.92Å; A44-Y124 PolarHBondContact N-O 3Å; A44-Y124 PolarHBondContact O-N 3.49Å
45	S	94.7	Very high	79.2	Confident	71 Å²	71	71.3 Å²	71.3	50%	0.497	46%	0.456	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.5	140.3	176	-169.6	0	0	0	0	109.3	I122 D123	S45-I122 WeakPolarHBondContact CA-O 2.99Å; S45-D123 VanDerWaalsContact CB-OD1 3.3Å; S45-D123 WeakPolarHBondContact CB-OD1 3.39Å; S45-D123 PolarHBondContact OG-OD1 3.11Å
46	V	95.6	Very high	81.9	Confident	10 Å²	10	68 Å²	68	6%	0.061	42%	0.42	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.8	140.8	178.7	63.7	0	0	0	0	109.9	L48 D84 L87 T121 I122 Y124	V46-L48 HydrophobicContact CG1-CG 4.32Å; V46-L48 HydrophobicContact CG2-CD2 3.74Å; V46-L48 HydrophobicContact CG2-CG 4.17Å; V46-D84 WeakPolarHBondContact CG2-OD2 3.46Å; V46-L87 HydrophobicContact CG1-CD1 4.34Å; V46-L87 HydrophobicContact CG1-CD2 3.88Å; V46-L87 HydrophobicContact CG1-CG 4.01Å; V46-T121 CarbonylContact O-C 3.55Å; V46-T121 WeakPolarHBondContact O-CA 3.46Å; V46-I122 HydrophobicContact CG1-CB 4.24Å; V46-I122 PolarHBondContact N-O 3.33Å; V46-I122 PolarHBondContact O-N 3.35Å; V46-Y124 HydrophobicContact CB-CE1 4Å; V46-Y124 HydrophobicContact CG1-CD1 4.08Å; V46-Y124 HydrophobicContact CG1-CE1 3.68Å
47	T	95.3	Very high	84.3	Confident	74 Å²	74	63.9 Å²	63.9	45%	0.454	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.5	108.8	172.6	-58.5	0	0	0	0	109.2	V120 T121	T47-V120 CarbonylContact C-O 3.5Å; T47-V120 WeakPolarHBondContact CA-O 3.3Å; T47-T121 PolarHBondContact OG1-OG1 3.06Å
48	L	93.8	Very high	86.5	Confident	1 Å²	1	60.7 Å²	60.7	1%	0.005	38%	0.381	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.9	136.4	-179.5	-60.6	176.2	0	0	0	110.4	V46 I56 A81 D84 L87 S119 V120 I122	V46-L48 HydrophobicContact CG1-CG 4.32Å; V46-L48 HydrophobicContact CG2-CD2 3.74Å; V46-L48 HydrophobicContact CG2-CG 4.17Å; L48-I56 HydrophobicContact CB-CG2 4.35Å; L48-I56 HydrophobicContact CD1-CB 4.47Å; L48-I56 HydrophobicContact CD1-CD1 4.25Å; L48-A81 HydrophobicContact CD1-CB 3.8Å; L48-D84 HydrophobicContact CD2-CB 3.5Å; L48-D84 VanDerWaalsContact CD2-CB 3.5Å; L48-L87 HydrophobicContact CD1-CD1 3.74Å; L48-S119 CarbonylContact O-C 3.57Å; L48-S119 VanDerWaalsContact O-CA 3.25Å; L48-S119 WeakPolarHBondContact O-CA 3.29Å; L48-S119 WeakPolarHBondContact O-CB 3.46Å; L48-V120 PolarHBondContact N-O 2.88Å; L48-V120 PolarHBondContact O-N 3.48Å; L48-I122 HydrophobicContact CD1-CD1 4.34Å
49	Q	92.6	Very high	88.4	Confident	115 Å²	115	59.2 Å²	59.2	54%	0.537	36%	0.36	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.5	145.8	171.4	-62.8	-61.2	-30.3	0	0	109.3	S80 G118	Q49-S80 WeakPolarHBondContact O-CB 3.22Å; Q49-S80 PolarHBondContact O-OG 2.95Å; Q49-G118 PolarHBondContact OE1-O 3.28Å
50	K	89	Confident	89.8	Confident	27 Å²	27	57.2 Å²	57.2	12%	0.117	35%	0.35	C	S	.	.	P	Polyproline II helix	trans	-83.9	146	175.9	-65.9	-167.8	166.6	-160.4	0	110.7	N54 L55 I56 I113 Q114 S116 G118 V120	K50-N54 WeakPolarHBondContact CD-OD1 3.48Å; K50-N54 PolarHBondContact NZ-ND2 2.87Å; K50-N54 PolarHBondContact NZ-O 3.05Å; K50-N54 PolarHBondContact NZ-OD1 3.46Å; K50-L55 WeakPolarHBondContact CA-O 3.4Å; K50-I56 HydrophobicContact CG-CG2 3.9Å; K50-I113 WeakPolarHBondContact CE-O 3.24Å; K50-I113 PolarHBondContact NZ-O 3.34Å; K50-Q114 PolarHBondContact NZ-O 2.9Å; K50-S116 WeakPolarHBondContact CE-O 3.21Å; K50-S116 WeakPolarHBondContact CE-OG 3.37Å; K50-S116 PolarHBondContact NZ-O 2.65Å; K50-G118 WeakPolarHBondContact CB-O 3.43Å; K50-G118 PolarHBondContact N-O 3.26Å; K50-V120 HydrophobicContact CD-CG2 4.33Å; K50-V120 HydrophobicContact CG-CG2 4.2Å
51	D	85.6	Confident	90.6	Very high	62 Å²	62	53.2 Å²	53.2	33%	0.332	33%	0.327	S	S	.	.			trans	-74.7	177.9	170.9	62.8	28.2	0	0	0	112.1	G53 N54 L55	D51-G53 PolarHBondContact O-N 3.46Å; D51-G53 VanDerWaalsContact O-N 3.13Å; D51-G53 VanDerWaalsContact OD1-C 3.31Å; D51-G53 VanDerWaalsContact OD1-CA 3.26Å; D51-G53 WeakPolarHBondContact OD1-CA 3.46Å; D51-G53 PolarHBondContact OD1-N 3.34Å; D51-N54 PolarHBondContact O-N 2.9Å; D51-N54 PolarHBondContact OD1-N 2.57Å; D51-N54 VanDerWaalsContact OD1-N 3.13Å; D51-L55 VanDerWaalsContact CG-O 3.25Å; D51-L55 PolarHBondContact N-O 2.95Å; D51-L55 WeakPolarHBondContact OD1-CA 3.32Å; D51-L55 PolarHBondContact OD1-N 3.21Å
52	D	82.5	Confident	91	Very high	181 Å²	181	51 Å²	51	97%	0.968	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.5	-23.7	178	-65.3	-31.3	0	0	0	112.9	N54	D52-N54 VanDerWaalsContact C-N 3.32Å
53	G	82.5	Confident	91.1	Very high	53 Å²	53	48.7 Å²	48.7	55%	0.546	30%	0.3	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.4	3.3	175.4	0	0	0	0	0	114.3	D51 L55	D51-G53 PolarHBondContact O-N 3.46Å; D51-G53 VanDerWaalsContact O-N 3.13Å; D51-G53 VanDerWaalsContact OD1-C 3.31Å; D51-G53 VanDerWaalsContact OD1-CA 3.26Å; D51-G53 WeakPolarHBondContact OD1-CA 3.46Å; D51-G53 PolarHBondContact OD1-N 3.34Å; G53-L55 PolarHBondContact O-N 3.36Å
54	N	83.2	Confident	90.9	Very high	68 Å²	68	45.2 Å²	45.2	36%	0.364	28%	0.278	S	S	.	.	S	Bend	trans	60	26.8	-172.4	-173.7	59.9	0	0	0	113.1	K50 D51 D52 Q114 S116	K50-N54 WeakPolarHBondContact CD-OD1 3.48Å; K50-N54 PolarHBondContact NZ-ND2 2.87Å; K50-N54 PolarHBondContact NZ-O 3.05Å; K50-N54 PolarHBondContact NZ-OD1 3.46Å; D51-N54 PolarHBondContact O-N 2.9Å; D51-N54 PolarHBondContact OD1-N 2.57Å; D51-N54 VanDerWaalsContact OD1-N 3.13Å; D52-N54 VanDerWaalsContact C-N 3.32Å; N54-Q114 PolarHBondContact ND2-O 3.27Å; N54-S116 PolarHBondContact OD1-O 3.04Å
55	L	87.7	Confident	90.6	Very high	94 Å²	94	49.4 Å²	49.4	49%	0.492	30%	0.302	S	S	.	.			trans	-106.9	162.5	177.4	-57.4	175.7	0	0	0	110.7	K50 D51 G53	K50-L55 WeakPolarHBondContact CA-O 3.4Å; D51-L55 VanDerWaalsContact CG-O 3.25Å; D51-L55 PolarHBondContact N-O 2.95Å; D51-L55 WeakPolarHBondContact OD1-CA 3.32Å; D51-L55 PolarHBondContact OD1-N 3.21Å; G53-L55 PolarHBondContact O-N 3.36Å
56	I	90.3	Very high	90.2	Very high	7 Å²	7	47.8 Å²	47.8	4%	0.036	29%	0.291	C	S	.	.			trans	-119.9	-1.1	173.2	60.1	168.2	0	0	0	112.3	L48 K50 I58 A81 I113 V120 I122	L48-I56 HydrophobicContact CB-CG2 4.35Å; L48-I56 HydrophobicContact CD1-CB 4.47Å; L48-I56 HydrophobicContact CD1-CD1 4.25Å; K50-I56 HydrophobicContact CG-CG2 3.9Å; I56-I58 HydrophobicContact CD1-CD1 3.55Å; I56-I58 HydrophobicContact CD1-CG1 3.83Å; I56-I58 HydrophobicContact CG1-CD1 4.25Å; I56-I58 HydrophobicContact CG1-CG1 3.96Å; I56-A81 WeakPolarHBondContact O-CB 3.46Å; I56-A81 PolarHBondContact O-N 2.72Å; I56-I113 HydrophobicContact CD1-CG2 3.61Å; I56-I113 HydrophobicContact CG1-CG2 4.07Å; I56-V120 HydrophobicContact CG2-CG2 4.09Å; I56-I122 HydrophobicContact CD1-CD1 3.79Å
57	G	91.8	Very high	89.9	Confident	13 Å²	13	47.4 Å²	47.4	13%	0.134	29%	0.288	C	S	.	.			trans	73.6	39.7	176.2	0	0	0	0	0	116.3	F76	G57-F76 PolarHBondContact O-N 3.26Å
58	I	94.5	Very high	89.7	Confident	27 Å²	27	46.8 Å²	46.8	14%	0.138	29%	0.285	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.4	152.3	174.9	69.1	175.8	0	0	0	112.8	I56 I60 L72 I75 A81 L87 I113 I122	I56-I58 HydrophobicContact CD1-CD1 3.55Å; I56-I58 HydrophobicContact CD1-CG1 3.83Å; I56-I58 HydrophobicContact CG1-CD1 4.25Å; I56-I58 HydrophobicContact CG1-CG1 3.96Å; I58-I60 HydrophobicContact CD1-CD1 4.14Å; I58-I60 HydrophobicContact CD1-CG1 4.18Å; I58-I60 HydrophobicContact CG1-CG1 4.36Å; I58-L72 HydrophobicContact CB-CD2 4.18Å; I58-L72 HydrophobicContact CD1-CD2 3.74Å; I58-L72 HydrophobicContact CG1-CD2 4.43Å; I58-I75 HydrophobicContact CG2-CG1 4.46Å; I58-A81 HydrophobicContact CG2-CB 3.41Å; I58-A81 VanDerWaalsContact CG2-CB 3.41Å; I58-L87 HydrophobicContact CG2-CD1 4.46Å; I58-I113 HydrophobicContact CD1-CD1 4.22Å; I58-I122 HydrophobicContact CD1-CD1 4.24Å
59	S	94.2	Very high	89.5	Confident	40 Å²	40	47 Å²	47	28%	0.28	29%	0.287	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.7	140.9	167.5	-176.6	0	0	0	0	110.2	V73 Q74	S59-V73 PolarHBondContact O-N 3.32Å; S59-Q74 PolarHBondContact N-O 3.04Å
60	I	94.5	Very high	89.6	Confident	18 Å²	18	41.7 Å²	41.7	9%	0.092	26%	0.262	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.3	141.4	-170.7	-56.8	175.2	0	0	0	109.6	I58 V70 Y71 L72 I93 R106 V109 I113	I58-I60 HydrophobicContact CD1-CD1 4.14Å; I58-I60 HydrophobicContact CD1-CG1 4.18Å; I58-I60 HydrophobicContact CG1-CG1 4.36Å; I60-V70 HydrophobicContact CG2-CG1 3.15Å; I60-Y71 CarbonylContact C-O 3.55Å; I60-Y71 WeakPolarHBondContact CA-O 3.48Å; I60-L72 HydrophobicContact CG1-CD2 4.5Å; I60-I93 HydrophobicContact CD1-CD1 3.85Å; I60-I93 HydrophobicContact CG1-CD1 4.06Å; I60-I93 HydrophobicContact CG2-CD1 4.32Å; I60-R106 HydrophobicContact CG2-CG 4.37Å; I60-R106 WeakPolarHBondContact O-CD 3.47Å; I60-V109 HydrophobicContact CD1-CG1 4.27Å; I60-I113 HydrophobicContact CD1-CD1 3.58Å
61	G	93	Very high	89.9	Confident	5 Å²	5	40.6 Å²	40.6	5%	0.052	26%	0.258	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.7	173.9	176.1	0	0	0	0	0	112.3	Y71	G61-Y71 PolarHBondContact N-O 3.28Å; G61-Y71 PolarHBondContact O-N 2.75Å; G61-Y71 VanDerWaalsContact O-N 3.09Å
62	G	92.3	Very high	90.4	Very high	17 Å²	17	37.7 Å²	37.7	18%	0.175	24%	0.242	C	C	.	.	E	Extended strand (participates in β ladder)	trans	70.9	-143.1	-177.1	0	0	0	0	0	113.7
63	G	91.8	Very high	91	Very high	1 Å²	1	30.2 Å²	30.2	1%	0.01	20%	0.203	C	C	.	.			trans	82.6	166.6	-174.1	0	0	0	0	0	114.5	S66 C67 C69	G63-S66 PolarHBondContact O-N 2.84Å; G63-S66 PolarHBondContact O-OG 3.45Å; G63-C67 CarbonylContact C-O 3.59Å; G63-C67 WeakPolarHBondContact CA-O 3.2Å; G63-C67 PolarHBondContact O-N 2.58Å; G63-C69 PolarHBondContact N-O 3.02Å
64	A	89.3	Confident	91.5	Very high	29 Å²	29	30.8 Å²	30.8	24%	0.24	19%	0.191	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67	150.5	-177.7	0	0	0	0	0	112.4	C67 G103 R104 T105	A64-C67 PolarHBondContact N-O 3Å; A64-G103 WeakPolarHBondContact CB-O 3.39Å; A64-R104 PolarHBondContact N-O 3.39Å; A64-T105 WeakPolarHBondContact O-CG2 3.3Å
65	P	87.7	Confident	92	Very high	124 Å²	124	28.6 Å²	28.6	81%	0.805	18%	0.179	S	C	*	.	T	Hydrogen-bonded Turn	cis	-85.7	-11.7	0.4	34.6	-35.6	0	0	0	114.9
66	S	86.4	Confident	92.2	Very high	38 Å²	38	28.8 Å²	28.8	27%	0.266	18%	0.176	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-39.6	-169.5	51.6	0	0	0	0	113.9	G63	G63-S66 PolarHBondContact O-N 2.84Å; G63-S66 PolarHBondContact O-OG 3.45Å
67	C	90.3	Very high	91.9	Very high	1 Å²	1	34.4 Å²	34.4	1%	0.007	20%	0.202	C	C	.	.			trans	-125.9	131	-174.9	-167.7	0	0	0	0	111.1	G63 A64 C69 V310	G63-C67 CarbonylContact C-O 3.59Å; G63-C67 WeakPolarHBondContact CA-O 3.2Å; G63-C67 PolarHBondContact O-N 2.58Å; A64-C67 PolarHBondContact N-O 3Å; C67-C69 PolarHBondContact O-N 3.21Å; C67-C69 VanDerWaalsContact SG-SG 3.63Å; C67-V310 HydrophobicContact CB-CG1 3.8Å; C67-V310 PolarHBondContact SG-O 2.93Å
68	P	89.6	Confident	91.6	Very high	61 Å²	61	40.9 Å²	40.9	40%	0.396	23%	0.234	S	C	.	.	S	Bend	trans	-68.1	-22.8	-177.6	27.6	-36.8	0	0	0	113.7	E311	P68-E311 WeakPolarHBondContact CD-O 3.41Å; P68-E311 VanDerWaalsContact CG-O 3.27Å; P68-E311 WeakPolarHBondContact CG-O 3.33Å
69	C	91.2	Very high	91.2	Very high	7 Å²	7	39.8 Å²	39.8	5%	0.047	23%	0.23	C	C	.	.	S	Bend	trans	-113.4	155	-179.3	61.4	0	0	0	0	111.7	G63 C67 E92 G313	G63-C69 PolarHBondContact N-O 3.02Å; C67-C69 PolarHBondContact O-N 3.21Å; C67-C69 VanDerWaalsContact SG-SG 3.63Å; C69-E92 HydrophobicContact CB-CG 4.09Å; C69-E92 WeakPolarHBondContact CB-OE1 3.45Å; C69-G313 VanDerWaalsContact SG-CA 3.53Å; C69-G313 PolarHBondContact SG-O 3.32Å; C69-G313 VanDerWaalsContact SG-O 3.4Å
70	V	94.9	Very high	91.1	Very high	2 Å²	2	39 Å²	39	1%	0.012	22%	0.224	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-111.4	129	173.8	178.3	0	0	0	0	106.8	I60 E92 I93 V101 V109	I60-V70 HydrophobicContact CG2-CG1 3.15Å; V70-E92 CarbonylContact O-C 3.58Å; V70-E92 WeakPolarHBondContact O-CA 3.41Å; V70-I93 HydrophobicContact CG1-CB 4.44Å; V70-I93 HydrophobicContact CG1-CD1 4.32Å; V70-I93 PolarHBondContact O-N 3.3Å; V70-V101 HydrophobicContact CB-CG2 4.37Å; V70-V109 HydrophobicContact CG1-CB 4.35Å; V70-V109 HydrophobicContact CG1-CG1 4.19Å; V70-V109 HydrophobicContact CG1-CG2 4.27Å; V70-V109 HydrophobicContact CG2-CG2 4.08Å
71	Y	94.9	Very high	91	Very high	4 Å²	4	38.1 Å²	38.1	2%	0.016	22%	0.22	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-138.9	162.4	-173.2	54.1	-94.5	0	0	0	112.6	I60 G61 V73 D91 N314 Y317 R318 L321	I60-Y71 CarbonylContact C-O 3.55Å; I60-Y71 WeakPolarHBondContact CA-O 3.48Å; G61-Y71 PolarHBondContact N-O 3.28Å; G61-Y71 PolarHBondContact O-N 2.75Å; G61-Y71 VanDerWaalsContact O-N 3.09Å; Y71-V73 HydrophobicContact CD2-CG2 4.34Å; Y71-V73 HydrophobicContact CE2-CG2 4.06Å; Y71-D91 CarbonylContact C-O 3.47Å; Y71-D91 WeakPolarHBondContact CA-O 3.19Å; Y71-D91 VanDerWaalsContact CB-O 3.28Å; Y71-D91 WeakPolarHBondContact CB-O 3.06Å; Y71-N314 HydrophobicContact CE1-CB 4.2Å; Y71-N314 PolarHBondContact OH-ND2 2.91Å; Y71-N314 VanDerWaalsContact OH-ND2 3.09Å; Y71-Y317 AromaticContact CE2-CD1 3.98Å; Y71-Y317 HydrophobicContact CE2-CD1 3.98Å; Y71-Y317 HydrophobicContact CE2-CE1 4.08Å; Y71-R318 HydrophobicContact CD1-CG 4.16Å; Y71-R318 HydrophobicContact CD2-CG 3.81Å; Y71-R318 HydrophobicContact CE1-CG 4.43Å; Y71-R318 HydrophobicContact CE2-CG 4.1Å; Y71-R318 HydrophobicContact CG-CG 3.85Å; Y71-L321 HydrophobicContact CD2-CD1 4.3Å; Y71-L321 HydrophobicContact CE2-CD1 4.17Å
72	L	95.8	Very high	90.9	Very high	2 Å²	2	39.8 Å²	39.8	1%	0.01	23%	0.233	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-78.4	124.1	178.9	-61.6	-178	0	0	0	110.9	I58 I60 L87 G90 D91 I93	I58-L72 HydrophobicContact CB-CD2 4.18Å; I58-L72 HydrophobicContact CD1-CD2 3.74Å; I58-L72 HydrophobicContact CG1-CD2 4.43Å; I60-L72 HydrophobicContact CG1-CD2 4.5Å; L72-L87 HydrophobicContact CD1-CB 3.71Å; L72-L87 HydrophobicContact CD1-CD1 4.07Å; L72-L87 HydrophobicContact CD1-CD2 4.13Å; L72-L87 HydrophobicContact CD1-CG 4.19Å; L72-G90 PolarHBondContact O-N 3.06Å; L72-D91 HydrophobicContact CD1-CB 4.16Å; L72-D91 PolarHBondContact N-O 3.35Å; L72-I93 HydrophobicContact CD2-CD1 3.83Å; L72-I93 HydrophobicContact CD2-CG1 4.17Å; L72-I93 HydrophobicContact CG-CG1 4.46Å
73	V	94.8	Very high	90.9	Very high	23 Å²	23	45.1 Å²	45.1	14%	0.139	26%	0.257	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.1	-42.7	175.9	173.1	0	0	0	0	110.7	S59 Y71 L321 R324	S59-V73 PolarHBondContact O-N 3.32Å; Y71-V73 HydrophobicContact CD2-CG2 4.34Å; Y71-V73 HydrophobicContact CE2-CG2 4.06Å; V73-L321 HydrophobicContact CB-CD1 4.46Å; V73-L321 HydrophobicContact CG1-CD2 4.16Å; V73-L321 HydrophobicContact CG2-CD1 4.37Å; V73-R324 PolarHBondContact O-NH2 2.95Å
74	Q	93.4	Very high	90.9	Very high	66 Å²	66	48.6 Å²	48.6	31%	0.308	28%	0.276	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-152.3	149.1	-176	-178.4	168.8	-10.3	0	0	110.3	S59	S59-Q74 PolarHBondContact N-O 3.04Å
75	I	93.2	Very high	91.1	Very high	22 Å²	22	49.4 Å²	49.4	11%	0.113	29%	0.287	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.3	126.6	168.4	-58.9	-178.7	0	0	0	106	I58 A81 A82 L87 E88	I58-I75 HydrophobicContact CG2-CG1 4.46Å; I75-A81 HydrophobicContact CG2-CB 4.15Å; I75-A82 HydrophobicContact CG2-CB 3.94Å; I75-L87 HydrophobicContact CD1-CB 3.89Å; I75-L87 WeakPolarHBondContact CD1-O 3Å; I75-E88 VanDerWaalsContact CD1-CA 3.49Å
76	F	91.7	Very high	91.3	Very high	97 Å²	97	45.4 Å²	45.4	43%	0.425	26%	0.262	S	S	.	.			trans	-82.1	137	-179.7	-64.7	-76.5	0	0	0	109.6	G57 G79 A82	G57-F76 PolarHBondContact O-N 3.26Å; F76-G79 PolarHBondContact O-N 3.45Å; F76-A82 WeakPolarHBondContact O-CB 3.37Å
77	E	85.3	Confident	91.8	Very high	125 Å²	125	43.8 Å²	43.8	58%	0.584	25%	0.25	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.7	148.4	173.5	-69.2	162.1	-155.2	0	0	109.4	G79 K328	E77-G79 PolarHBondContact O-N 3.1Å; E77-K328 WeakPolarHBondContact OE1-CE 3.38Å; E77-K328 IonicContact OE1-NZ 3.62Å; E77-K328 PolarHBondContact OE1-NZ 3.23Å
78	N	84.2	Confident	92	Very high	150 Å²	150	45.6 Å²	45.6	80%	0.802	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.7	11.7	-174.4	-49.4	-40.6	0	0	0	115.8
79	G	87	Confident	92.2	Very high	4 Å²	4	42.8 Å²	42.8	4%	0.041	24%	0.241	C	C	.	.	S	Bend	trans	-92.3	154.1	171.3	0	0	0	0	0	112.4	F76 E77 A81 A82 D83	F76-G79 PolarHBondContact O-N 3.45Å; E77-G79 PolarHBondContact O-N 3.1Å; G79-A81 PolarHBondContact O-N 3.36Å; G79-A81 VanDerWaalsContact O-N 3.1Å; G79-A82 WeakPolarHBondContact O-CA 3.43Å; G79-A82 WeakPolarHBondContact O-CB 3.46Å; G79-A82 PolarHBondContact O-N 3.1Å; G79-D83 PolarHBondContact O-N 3.34Å; G79-D83 VanDerWaalsContact O-N 3.14Å
80	S	91	Very high	92.3	Very high	22 Å²	22	42.5 Å²	42.5	15%	0.154	24%	0.238	C	C	.	.	H	α-helix	trans	-55.1	-34	179.2	175.1	0	0	0	0	113.9	Q49 A82 D83 D84	Q49-S80 WeakPolarHBondContact O-CB 3.22Å; Q49-S80 PolarHBondContact O-OG 2.95Å; S80-A82 VanDerWaalsContact C-N 3.31Å; S80-A82 PolarHBondContact O-N 3.21Å; S80-D83 PolarHBondContact O-N 3.45Å; S80-D84 WeakPolarHBondContact O-CB 3.41Å; S80-D84 PolarHBondContact O-N 3.47Å
81	A	92.6	Very high	92.3	Very high	1 Å²	1	42.4 Å²	42.4	1%	0.008	24%	0.238	C	C	.	.	H	α-helix	trans	-65.7	-32.4	175.1	0	0	0	0	0	113.2	L48 I56 I58 I75 G79 G85 L87	L48-A81 HydrophobicContact CD1-CB 3.8Å; I56-A81 WeakPolarHBondContact O-CB 3.46Å; I56-A81 PolarHBondContact O-N 2.72Å; I58-A81 HydrophobicContact CG2-CB 3.41Å; I58-A81 VanDerWaalsContact CG2-CB 3.41Å; I75-A81 HydrophobicContact CG2-CB 4.15Å; G79-A81 PolarHBondContact O-N 3.36Å; G79-A81 VanDerWaalsContact O-N 3.1Å; A81-G85 PolarHBondContact O-N 2.93Å; A81-L87 HydrophobicContact CB-CD1 4.41Å
82	A	91.6	Very high	92.3	Very high	40 Å²	40	44.6 Å²	44.6	33%	0.331	25%	0.248	S	C	.	.	H	α-helix	trans	-72.9	-40.6	175.8	0	0	0	0	0	111.4	I75 F76 G79 S80 G85	I75-A82 HydrophobicContact CG2-CB 3.94Å; F76-A82 WeakPolarHBondContact O-CB 3.37Å; G79-A82 WeakPolarHBondContact O-CA 3.43Å; G79-A82 WeakPolarHBondContact O-CB 3.46Å; G79-A82 PolarHBondContact O-N 3.1Å; S80-A82 VanDerWaalsContact C-N 3.31Å; S80-A82 PolarHBondContact O-N 3.21Å; A82-G85 PolarHBondContact O-N 2.96Å
83	D	91.3	Very high	92.4	Very high	129 Å²	129	44.7 Å²	44.7	69%	0.69	25%	0.249	S	C	*	.	H	α-helix	trans	-66.2	-39.6	179.6	-64.7	-21.2	0	0	0	112.4	G79 S80	G79-D83 PolarHBondContact O-N 3.34Å; G79-D83 VanDerWaalsContact O-N 3.14Å; S80-D83 PolarHBondContact O-N 3.45Å
84	D	93.2	Very high	92.4	Very high	73 Å²	73	45.1 Å²	45.1	39%	0.39	25%	0.251	S	S	.	.	H	α-helix	trans	-70.1	-39	175.3	175.4	89.6	0	0	0	112	V46 L48 S80 S86	V46-D84 WeakPolarHBondContact CG2-OD2 3.46Å; L48-D84 HydrophobicContact CD2-CB 3.5Å; L48-D84 VanDerWaalsContact CD2-CB 3.5Å; S80-D84 WeakPolarHBondContact O-CB 3.41Å; S80-D84 PolarHBondContact O-N 3.47Å; D84-S86 PolarHBondContact O-N 3.32Å; D84-S86 WeakPolarHBondContact OD2-CB 3.34Å; D84-S86 PolarHBondContact OD2-N 3.43Å; D84-S86 PolarHBondContact OD2-OG 3.16Å
85	G	92.1	Very high	92.5	Very high	46 Å²	46	47 Å²	47	47%	0.474	26%	0.255	S	S	.	.			trans	74.2	-0.3	174.6	0	0	0	0	0	115.8	A81 A82	A81-G85 PolarHBondContact O-N 2.93Å; A82-G85 PolarHBondContact O-N 2.96Å
86	S	93.6	Very high	92.6	Very high	41 Å²	41	46 Å²	46	29%	0.287	25%	0.251	S	S	.	.			trans	-71.9	-35.6	179.6	-57.5	0	0	0	0	113.1	D84 Y124 K126	D84-S86 PolarHBondContact O-N 3.32Å; D84-S86 WeakPolarHBondContact OD2-CB 3.34Å; D84-S86 PolarHBondContact OD2-N 3.43Å; D84-S86 PolarHBondContact OD2-OG 3.16Å; S86-Y124 PolarHBondContact O-OH 2.97Å; S86-K126 PolarHBondContact O-NZ 3.38Å
87	L	95.3	Very high	92.7	Very high	3 Å²	3	44.4 Å²	44.4	2%	0.016	25%	0.247	C	C	.	.			trans	-87.6	144.3	-179.1	-64.9	-176.7	0	0	0	111.3	V46 L48 I58 L72 I75 A81 I122 Y124	V46-L87 HydrophobicContact CG1-CD1 4.34Å; V46-L87 HydrophobicContact CG1-CD2 3.88Å; V46-L87 HydrophobicContact CG1-CG 4.01Å; L48-L87 HydrophobicContact CD1-CD1 3.74Å; I58-L87 HydrophobicContact CG2-CD1 4.46Å; L72-L87 HydrophobicContact CD1-CB 3.71Å; L72-L87 HydrophobicContact CD1-CD1 4.07Å; L72-L87 HydrophobicContact CD1-CD2 4.13Å; L72-L87 HydrophobicContact CD1-CG 4.19Å; I75-L87 HydrophobicContact CD1-CB 3.89Å; I75-L87 WeakPolarHBondContact CD1-O 3Å; A81-L87 HydrophobicContact CB-CD1 4.41Å; L87-I122 HydrophobicContact CD1-CD1 4.19Å; L87-Y124 HydrophobicContact CD2-CD1 3.42Å; L87-Y124 VanDerWaalsContact CD2-CD1 3.42Å; L87-Y124 HydrophobicContact CD2-CD2 3.94Å; L87-Y124 HydrophobicContact CD2-CE1 3.6Å; L87-Y124 HydrophobicContact CD2-CE2 4.08Å; L87-Y124 HydrophobicContact CD2-CG 3.61Å
88	E	94.8	Very high	93	Very high	40 Å²	40	49.3 Å²	49.3	19%	0.187	26%	0.26	C	S	.	.			trans	-143.7	161.2	175.1	-71	178.7	122.1	0	0	112.2	I75 G90 D91 K126 R322 K329	I75-E88 VanDerWaalsContact CD1-CA 3.49Å; E88-G90 PolarHBondContact O-N 2.86Å; E88-D91 PolarHBondContact N-OD2 3.02Å; E88-D91 WeakPolarHBondContact O-CB 3.3Å; E88-D91 PolarHBondContact O-N 3.21Å; E88-K126 WeakPolarHBondContact OE2-CE 3.5Å; E88-K126 IonicContact OE2-NZ 3.74Å; E88-K126 PolarHBondContact OE2-NZ 2.97Å; E88-R322 PolarHBondContact O-NH2 2.89Å; E88-R322 IonicContact OE1-NH1 2.66Å; E88-R322 IonicContact OE2-CZ 3.98Å; E88-R322 IonicContact OE2-NH1 2.61Å; E88-R322 PolarHBondContact OE2-NH1 3.44Å; E88-K329 IonicContact OE1-NZ 3.16Å; E88-K329 PolarHBondContact OE1-NZ 3.09Å; E88-K329 VanDerWaalsContact OE1-NZ 3.16Å
89	A	94.3	Very high	93.5	Very high	2 Å²	2	45.4 Å²	45.4	2%	0.017	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.6	137.3	-175.9	0	0	0	0	0	111.4	L321 R322 Q325	A89-L321 HydrophobicContact CB-CB 4.17Å; A89-R322 PolarHBondContact O-NE 3.27Å; A89-R322 PolarHBondContact O-NH2 3.07Å; A89-Q325 HydrophobicContact CB-CB 4.22Å
90	G	93.6	Very high	93.9	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	26%	0.26	C	S	.	.	T	Hydrogen-bonded Turn	trans	88	-8.5	-173.8	0	0	0	0	0	115.1	L72 E88 R318	L72-G90 PolarHBondContact O-N 3.06Å; E88-G90 PolarHBondContact O-N 2.86Å; G90-R318 VanDerWaalsContact O-CZ 3.31Å; G90-R318 PolarHBondContact O-NE 3.35Å; G90-R318 PolarHBondContact O-NH2 3.19Å
91	D	95.6	Very high	94	Very high	1 Å²	1	48.1 Å²	48.1	1%	0.005	25%	0.253	C	S	.	.	P	Polyproline II helix	trans	-66.1	140.3	172.9	-66.7	-20.5	0	0	0	110.1	Y71 L72 E88 Y124 K126 L127 R322	Y71-D91 CarbonylContact C-O 3.47Å; Y71-D91 WeakPolarHBondContact CA-O 3.19Å; Y71-D91 VanDerWaalsContact CB-O 3.28Å; Y71-D91 WeakPolarHBondContact CB-O 3.06Å; L72-D91 HydrophobicContact CD1-CB 4.16Å; L72-D91 PolarHBondContact N-O 3.35Å; E88-D91 PolarHBondContact N-OD2 3.02Å; E88-D91 WeakPolarHBondContact O-CB 3.3Å; E88-D91 PolarHBondContact O-N 3.21Å; D91-Y124 HydrophobicContact CB-CD2 4.28Å; D91-K126 WeakPolarHBondContact OD1-CA 3.49Å; D91-K126 WeakPolarHBondContact OD2-CD 3.29Å; D91-K126 IonicContact OD2-NZ 3.61Å; D91-K126 PolarHBondContact OD2-NZ 3.33Å; D91-K126 VanDerWaalsContact OD2-NZ 3.12Å; D91-L127 PolarHBondContact OD1-N 3.06Å; D91-R322 VanDerWaalsContact CG-NH2 3.31Å; D91-R322 IonicContact OD1-CZ 3.27Å; D91-R322 IonicContact OD1-NH2 2.64Å; D91-R322 PolarHBondContact OD1-NH2 2.97Å; D91-R322 IonicContact OD2-NH2 2.77Å
92	E	95.1	Very high	93.9	Very high	49 Å²	49	55.7 Å²	55.7	23%	0.229	29%	0.286	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.7	131.3	178.9	163.7	-174.8	-153.6	0	0	110.5	C69 V70 V94 Y124 N125 R318	C69-E92 HydrophobicContact CB-CG 4.09Å; C69-E92 WeakPolarHBondContact CB-OE1 3.45Å; V70-E92 CarbonylContact O-C 3.58Å; V70-E92 WeakPolarHBondContact O-CA 3.41Å; E92-V94 HydrophobicContact CG-CG2 4.38Å; E92-Y124 CarbonylContact O-C 3.51Å; E92-Y124 WeakPolarHBondContact O-CA 3.42Å; E92-Y124 VanDerWaalsContact O-CB 3.25Å; E92-Y124 WeakPolarHBondContact O-CB 3.29Å; E92-N125 HydrophobicContact CB-CB 4.22Å; E92-N125 PolarHBondContact N-O 3.02Å; E92-N125 VanDerWaalsContact N-O 3.07Å; E92-N125 PolarHBondContact O-N 3.46Å; E92-N125 PolarHBondContact OE2-ND2 2.94Å; E92-R318 VanDerWaalsContact CB-NH2 3.32Å
93	I	96	Very high	93.8	Very high	4 Å²	4	56.4 Å²	56.4	2%	0.021	30%	0.297	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.6	120.5	172.6	-55.6	179.8	0	0	0	108.5	I60 V70 L72 V96 V101 I122	I60-I93 HydrophobicContact CD1-CD1 3.85Å; I60-I93 HydrophobicContact CG1-CD1 4.06Å; I60-I93 HydrophobicContact CG2-CD1 4.32Å; V70-I93 HydrophobicContact CG1-CB 4.44Å; V70-I93 HydrophobicContact CG1-CD1 4.32Å; V70-I93 PolarHBondContact O-N 3.3Å; L72-I93 HydrophobicContact CD2-CD1 3.83Å; L72-I93 HydrophobicContact CD2-CG1 4.17Å; L72-I93 HydrophobicContact CG-CG1 4.46Å; I93-V96 HydrophobicContact CG2-CG2 3.95Å; I93-V101 HydrophobicContact CB-CG2 4.34Å; I93-V101 HydrophobicContact CG2-CG2 3.89Å; I93-V101 WeakPolarHBondContact O-CG2 3.26Å; I93-I122 HydrophobicContact CG2-CG2 4.12Å
94	V	95.6	Very high	93.9	Very high	32 Å²	32	55.3 Å²	55.3	19%	0.194	28%	0.283	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101	-44.1	-179.9	-174.8	0	0	0	0	110.9	E92 N100 V101 D123 N125	E92-V94 HydrophobicContact CG-CG2 4.38Å; V94-N100 PolarHBondContact O-OD1 2.96Å; V94-N100 VanDerWaalsContact O-OD1 3.14Å; V94-V101 PolarHBondContact O-N 3.42Å; V94-D123 PolarHBondContact N-O 3.27Å; V94-N125 HydrophobicContact CG2-CB 4.38Å; V94-N125 WeakPolarHBondContact CG2-ND2 3.49Å
95	R	95.9	Very high	93.9	Very high	105 Å²	105	54 Å²	54	40%	0.396	28%	0.278	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.2	149.9	177.5	-47.8	-166.2	-178.3	81.3	4.5	112.4	V99 I122 D123	R95-V99 CarbonylContact C-O 3.58Å; R95-V99 WeakPolarHBondContact CA-O 3.38Å; R95-V99 WeakPolarHBondContact CB-O 2.97Å; R95-I122 WeakPolarHBondContact O-CA 3.47Å; R95-D123 HydrophobicContact CB-CB 3.83Å; R95-D123 WeakPolarHBondContact CD-OD2 3.39Å; R95-D123 HydrophobicContact CG-CB 4.12Å; R95-D123 PolarHBondContact N-O 2.61Å; R95-D123 VanDerWaalsContact N-O 3.09Å; R95-D123 IonicContact NH1-OD2 3.17Å; R95-D123 PolarHBondContact NH1-OD2 3.24Å; R95-D123 VanDerWaalsContact NH1-OD2 3.11Å; R95-D123 PolarHBondContact O-N 2.71Å
96	V	95.3	Very high	93.9	Very high	3 Å²	3	58.4 Å²	58.4	2%	0.018	28%	0.28	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.9	122	169.1	175.8	0	0	0	0	107.9	I93 R98 V99 V101 V109 M112 I113 V120 T121	I93-V96 HydrophobicContact CG2-CG2 3.95Å; V96-R98 VanDerWaalsContact C-N 3.26Å; V96-R98 PolarHBondContact O-N 3.39Å; V96-V99 PolarHBondContact N-O 3.36Å; V96-V99 WeakPolarHBondContact O-CB 3.25Å; V96-V99 PolarHBondContact O-N 3Å; V96-V101 HydrophobicContact CB-CG1 4.16Å; V96-V101 HydrophobicContact CG2-CG1 3.81Å; V96-V109 HydrophobicContact CG2-CG1 4.18Å; V96-M112 HydrophobicContact CG1-CB 4.33Å; V96-I113 HydrophobicContact CG1-CG1 3.79Å; V96-I113 HydrophobicContact CG2-CD1 4.23Å; V96-I113 HydrophobicContact CG2-CG1 3.93Å; V96-V120 HydrophobicContact CG1-CG1 3.85Å; V96-T121 CarbonylContact C-O 3.56Å; V96-T121 WeakPolarHBondContact CA-O 3.37Å
97	N	94	Very high	93.9	Very high	63 Å²	63	59.8 Å²	59.8	34%	0.337	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	48.5	47	-176.2	-66.7	-29.8	0	0	0	112.8	V99 S116 T121	N97-V99 PolarHBondContact O-N 3.48Å; N97-S116 WeakPolarHBondContact ND2-CB 3.47Å; N97-T121 PolarHBondContact N-O 2.88Å; N97-T121 PolarHBondContact OD1-N 3.39Å
98	R	91.7	Very high	93.8	Very high	227 Å²	227	62.4 Å²	62.4	86%	0.857	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.6	3.1	-177.3	-49.2	175.1	179.8	-177.3	-1.4	115.2	V96	V96-R98 VanDerWaalsContact C-N 3.26Å; V96-R98 PolarHBondContact O-N 3.39Å
99	V	94.6	Very high	93.8	Very high	69 Å²	69	60.5 Å²	60.5	42%	0.418	29%	0.293	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.1	124.9	174.7	-176.8	0	0	0	0	109.6	R95 V96 N97 V101 M112	R95-V99 CarbonylContact C-O 3.58Å; R95-V99 WeakPolarHBondContact CA-O 3.38Å; R95-V99 WeakPolarHBondContact CB-O 2.97Å; V96-V99 PolarHBondContact N-O 3.36Å; V96-V99 WeakPolarHBondContact O-CB 3.25Å; V96-V99 PolarHBondContact O-N 3Å; N97-V99 PolarHBondContact O-N 3.48Å; V99-V101 PolarHBondContact O-N 3.32Å; V99-M112 HydrophobicContact CG1-SD 4.33Å
100	N	93.9	Very high	93.7	Very high	82 Å²	82	61.8 Å²	61.8	44%	0.439	30%	0.304	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-65.1	131.6	176	-170.9	-3.7	0	0	0	110.9	V94 K102	V94-N100 PolarHBondContact O-OD1 2.96Å; V94-N100 VanDerWaalsContact O-OD1 3.14Å; N100-K102 WeakPolarHBondContact OD1-CB 3.26Å; N100-K102 PolarHBondContact OD1-N 3.46Å
101	V	94.1	Very high	93.7	Very high	1 Å²	1	69 Å²	69	1%	0.006	33%	0.331	C	S	.	.			trans	-100	-4.2	-179.5	-51.9	0	0	0	0	113.7	V70 I93 V94 V96 V99 G103 R104 V109 M112	V70-V101 HydrophobicContact CB-CG2 4.37Å; I93-V101 HydrophobicContact CB-CG2 4.34Å; I93-V101 HydrophobicContact CG2-CG2 3.89Å; I93-V101 WeakPolarHBondContact O-CG2 3.26Å; V94-V101 PolarHBondContact O-N 3.42Å; V96-V101 HydrophobicContact CB-CG1 4.16Å; V96-V101 HydrophobicContact CG2-CG1 3.81Å; V99-V101 PolarHBondContact O-N 3.32Å; V101-G103 PolarHBondContact O-N 3.27Å; V101-R104 VanDerWaalsContact O-CB 3.22Å; V101-R104 WeakPolarHBondContact O-CB 3.29Å; V101-R104 WeakPolarHBondContact O-CG 3.39Å; V101-R104 PolarHBondContact O-N 3.02Å; V101-V109 HydrophobicContact CB-CG1 4.5Å; V101-V109 HydrophobicContact CB-CG2 3.76Å; V101-V109 HydrophobicContact CG1-CG1 4.19Å; V101-V109 HydrophobicContact CG1-CG2 4.12Å; V101-V109 HydrophobicContact CG2-CG2 4.42Å; V101-M112 HydrophobicContact CB-CE 4.33Å; V101-M112 HydrophobicContact CG1-CE 3.67Å
102	K	89.8	Confident	93.5	Very high	160 Å²	160	71.2 Å²	71.2	70%	0.696	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.9	130.8	177.2	-173.3	172.4	-177	174.6	0	110.9	N100 R104	N100-K102 WeakPolarHBondContact OD1-CB 3.26Å; N100-K102 PolarHBondContact OD1-N 3.46Å; K102-R104 VanDerWaalsContact C-N 3.26Å; K102-R104 PolarHBondContact O-N 3.35Å
103	G	89.4	Confident	93.4	Very high	54 Å²	54	69.4 Å²	69.4	56%	0.557	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	77.6	1.5	-177.8	0	0	0	0	0	115.2	A64 V101	A64-G103 WeakPolarHBondContact CB-O 3.39Å; V101-G103 PolarHBondContact O-N 3.27Å
104	R	93.8	Very high	93.1	Very high	106 Å²	106	74.2 Å²	74.2	40%	0.4	36%	0.356	S	S	.	.			trans	-83.4	155.1	171.7	-62	-68.5	-167.8	149.1	3.1	110.8	A64 V101 K102 E108 V109 M112	A64-R104 PolarHBondContact N-O 3.39Å; V101-R104 VanDerWaalsContact O-CB 3.22Å; V101-R104 WeakPolarHBondContact O-CB 3.29Å; V101-R104 WeakPolarHBondContact O-CG 3.39Å; V101-R104 PolarHBondContact O-N 3.02Å; K102-R104 VanDerWaalsContact C-N 3.26Å; K102-R104 PolarHBondContact O-N 3.35Å; R104-E108 WeakPolarHBondContact CA-OE2 3.38Å; R104-E108 HydrophobicContact CB-CB 4.32Å; R104-E108 WeakPolarHBondContact CD-OE2 3.39Å; R104-E108 IonicContact NH1-OE2 2.73Å; R104-V109 HydrophobicContact CB-CG2 3.87Å; R104-M112 HydrophobicContact CG-CE 4.32Å
105	T	94.1	Very high	92.8	Very high	45 Å²	45	76.4 Å²	76.4	28%	0.276	38%	0.377	S	S	.	.			trans	-75.9	154.6	173	69.4	0	0	0	0	110.8	A64 S107 E108 V109	A64-T105 WeakPolarHBondContact O-CG2 3.3Å; T105-S107 PolarHBondContact O-N 2.75Å; T105-E108 PolarHBondContact N-OE2 3.17Å; T105-E108 VanDerWaalsContact N-OE2 3.07Å; T105-E108 WeakPolarHBondContact O-CB 3.4Å; T105-E108 PolarHBondContact O-N 3.08Å; T105-E108 VanDerWaalsContact O-N 3.07Å; T105-E108 WeakPolarHBondContact OG1-CB 3.46Å; T105-E108 VanDerWaalsContact OG1-CG 3.22Å; T105-E108 WeakPolarHBondContact OG1-CG 3.45Å; T105-E108 PolarHBondContact OG1-N 2.91Å; T105-V109 PolarHBondContact O-N 3.16Å; T105-V109 VanDerWaalsContact O-N 3.09Å
106	R	91.4	Very high	92.3	Very high	140 Å²	140	72.2 Å²	72.2	53%	0.528	36%	0.364	S	S	.	.	H	α-helix	trans	-49	-45.3	173.1	176.9	179	63.1	176.9	-0.3	112.2	I60 E108 V109 A110	I60-R106 HydrophobicContact CG2-CG 4.37Å; I60-R106 WeakPolarHBondContact O-CD 3.47Å; R106-E108 PolarHBondContact O-N 3.19Å; R106-V109 PolarHBondContact O-N 3.27Å; R106-A110 WeakPolarHBondContact O-CB 2.99Å; R106-A110 PolarHBondContact O-N 2.93Å
107	S	93.1	Very high	91.8	Very high	70 Å²	70	81.3 Å²	81.3	49%	0.49	40%	0.404	S	S	.	.	H	α-helix	trans	-68.3	-32.2	-178.2	-53.2	0	0	0	0	113	T105 R111	T105-S107 PolarHBondContact O-N 2.75Å; S107-R111 WeakPolarHBondContact O-CB 3.4Å; S107-R111 VanDerWaalsContact O-CG 3.29Å; S107-R111 WeakPolarHBondContact O-CG 3.2Å; S107-R111 PolarHBondContact O-N 3.29Å; S107-R111 PolarHBondContact O-NE 3.39Å
108	E	94.1	Very high	91.5	Very high	57 Å²	57	80.5 Å²	80.5	27%	0.266	41%	0.41	S	S	.	.	H	α-helix	trans	-67.3	-44.8	171.6	-75.4	171.9	165	0	0	111.8	R104 T105 R106 R111 M112	R104-E108 WeakPolarHBondContact CA-OE2 3.38Å; R104-E108 HydrophobicContact CB-CB 4.32Å; R104-E108 WeakPolarHBondContact CD-OE2 3.39Å; R104-E108 IonicContact NH1-OE2 2.73Å; T105-E108 PolarHBondContact N-OE2 3.17Å; T105-E108 VanDerWaalsContact N-OE2 3.07Å; T105-E108 WeakPolarHBondContact O-CB 3.4Å; T105-E108 PolarHBondContact O-N 3.08Å; T105-E108 VanDerWaalsContact O-N 3.07Å; T105-E108 WeakPolarHBondContact OG1-CB 3.46Å; T105-E108 VanDerWaalsContact OG1-CG 3.22Å; T105-E108 WeakPolarHBondContact OG1-CG 3.45Å; T105-E108 PolarHBondContact OG1-N 2.91Å; R106-E108 PolarHBondContact O-N 3.19Å; E108-R111 PolarHBondContact O-N 2.7Å; E108-M112 WeakPolarHBondContact O-CG 3.36Å; E108-M112 PolarHBondContact O-N 3.12Å
109	V	93.8	Very high	91.6	Very high	0 Å²	0	71.7 Å²	71.7	0%	0	38%	0.383	C	S	.	.	H	α-helix	trans	-63.7	-44.6	177.9	-177.1	0	0	0	0	111.4	I60 V70 V96 V101 R104 T105 R106 R111 M112 I113	I60-V109 HydrophobicContact CD1-CG1 4.27Å; V70-V109 HydrophobicContact CG1-CB 4.35Å; V70-V109 HydrophobicContact CG1-CG1 4.19Å; V70-V109 HydrophobicContact CG1-CG2 4.27Å; V70-V109 HydrophobicContact CG2-CG2 4.08Å; V96-V109 HydrophobicContact CG2-CG1 4.18Å; V101-V109 HydrophobicContact CB-CG1 4.5Å; V101-V109 HydrophobicContact CB-CG2 3.76Å; V101-V109 HydrophobicContact CG1-CG1 4.19Å; V101-V109 HydrophobicContact CG1-CG2 4.12Å; V101-V109 HydrophobicContact CG2-CG2 4.42Å; R104-V109 HydrophobicContact CB-CG2 3.87Å; T105-V109 PolarHBondContact O-N 3.16Å; T105-V109 VanDerWaalsContact O-N 3.09Å; R106-V109 PolarHBondContact O-N 3.27Å; V109-R111 VanDerWaalsContact C-N 3.32Å; V109-R111 PolarHBondContact O-N 3.45Å; V109-M112 HydrophobicContact CB-CE 4.18Å; V109-M112 HydrophobicContact CG1-CE 4.47Å; V109-M112 HydrophobicContact CG2-CE 3.83Å; V109-M112 PolarHBondContact O-N 3.35Å; V109-I113 HydrophobicContact CG1-CD1 4.18Å; V109-I113 WeakPolarHBondContact O-CG1 3.43Å; V109-I113 PolarHBondContact O-N 3.35Å
110	A	92.8	Very high	91.6	Very high	30 Å²	30	68.4 Å²	68.4	25%	0.248	36%	0.363	C	S	.	.	H	α-helix	trans	-57.1	-45.1	174	0	0	0	0	0	111.7	R106 I113 Q114	R106-A110 WeakPolarHBondContact O-CB 2.99Å; R106-A110 PolarHBondContact O-N 2.93Å; A110-I113 PolarHBondContact O-N 3.49Å; A110-Q114 WeakPolarHBondContact O-CB 3.48Å; A110-Q114 VanDerWaalsContact O-CG 3.3Å; A110-Q114 WeakPolarHBondContact O-CG 3.45Å; A110-Q114 PolarHBondContact O-N 3.37Å
111	R	92.8	Very high	91.6	Very high	152 Å²	152	66.2 Å²	66.2	57%	0.574	35%	0.353	S	S	*	.	H	α-helix	trans	-63.5	-39.7	175.5	-77.5	-177.2	-64.5	-169.2	4.1	112.9	S107 E108 V109 I113 Q114 A115	S107-R111 WeakPolarHBondContact O-CB 3.4Å; S107-R111 VanDerWaalsContact O-CG 3.29Å; S107-R111 WeakPolarHBondContact O-CG 3.2Å; S107-R111 PolarHBondContact O-N 3.29Å; S107-R111 PolarHBondContact O-NE 3.39Å; E108-R111 PolarHBondContact O-N 2.7Å; V109-R111 VanDerWaalsContact C-N 3.32Å; V109-R111 PolarHBondContact O-N 3.45Å; R111-I113 VanDerWaalsContact C-N 3.32Å; R111-I113 PolarHBondContact O-N 3.04Å; R111-Q114 PolarHBondContact O-N 3.13Å; R111-A115 WeakPolarHBondContact O-CB 3.28Å; R111-A115 PolarHBondContact O-N 3.31Å
112	M	92.1	Very high	91.7	Very high	46 Å²	46	66.2 Å²	66.2	23%	0.227	35%	0.353	C	S	.	.	H	α-helix	trans	-60.6	-42	176.3	-73.9	-171.8	-67.9	0	0	111.7	V96 V99 V101 R104 E108 V109	V96-M112 HydrophobicContact CG1-CB 4.33Å; V99-M112 HydrophobicContact CG1-SD 4.33Å; V101-M112 HydrophobicContact CB-CE 4.33Å; V101-M112 HydrophobicContact CG1-CE 3.67Å; R104-M112 HydrophobicContact CG-CE 4.32Å; E108-M112 WeakPolarHBondContact O-CG 3.36Å; E108-M112 PolarHBondContact O-N 3.12Å; V109-M112 HydrophobicContact CB-CE 4.18Å; V109-M112 HydrophobicContact CG1-CE 4.47Å; V109-M112 HydrophobicContact CG2-CE 3.83Å; V109-M112 PolarHBondContact O-N 3.35Å
113	I	92.3	Very high	92.1	Very high	11 Å²	11	60 Å²	60	6%	0.056	33%	0.327	C	S	.	.	H	α-helix	trans	-66.4	-47.9	176.1	-65.7	169.5	0	0	0	110	K50 I56 I58 I60 V96 V109 A110 R111 A115 S116 V120	K50-I113 WeakPolarHBondContact CE-O 3.24Å; K50-I113 PolarHBondContact NZ-O 3.34Å; I56-I113 HydrophobicContact CD1-CG2 3.61Å; I56-I113 HydrophobicContact CG1-CG2 4.07Å; I58-I113 HydrophobicContact CD1-CD1 4.22Å; I60-I113 HydrophobicContact CD1-CD1 3.58Å; V96-I113 HydrophobicContact CG1-CG1 3.79Å; V96-I113 HydrophobicContact CG2-CD1 4.23Å; V96-I113 HydrophobicContact CG2-CG1 3.93Å; V109-I113 HydrophobicContact CG1-CD1 4.18Å; V109-I113 WeakPolarHBondContact O-CG1 3.43Å; V109-I113 PolarHBondContact O-N 3.35Å; A110-I113 PolarHBondContact O-N 3.49Å; R111-I113 VanDerWaalsContact C-N 3.32Å; R111-I113 PolarHBondContact O-N 3.04Å; I113-A115 PolarHBondContact O-N 2.98Å; I113-S116 PolarHBondContact O-N 3.45Å; I113-S116 PolarHBondContact O-OG 3.44Å; I113-V120 HydrophobicContact CG1-CG1 4.37Å; I113-V120 HydrophobicContact CG2-CG1 4.34Å; I113-V120 HydrophobicContact CG2-CG2 4.26Å
114	Q	89.9	Confident	92.4	Very high	105 Å²	105	58.3 Å²	58.3	49%	0.491	30%	0.304	S	S	.	.	H	α-helix	trans	-65.2	-35	-179	-72.8	173	-13.6	0	0	113.5	K50 N54 A110 R111 S116	K50-Q114 PolarHBondContact NZ-O 2.9Å; N54-Q114 PolarHBondContact ND2-O 3.27Å; A110-Q114 WeakPolarHBondContact O-CB 3.48Å; A110-Q114 VanDerWaalsContact O-CG 3.3Å; A110-Q114 WeakPolarHBondContact O-CG 3.45Å; A110-Q114 PolarHBondContact O-N 3.37Å; R111-Q114 PolarHBondContact O-N 3.13Å; Q114-S116 PolarHBondContact O-N 3.04Å
115	A	89.3	Confident	92.4	Very high	78 Å²	78	54.5 Å²	54.5	65%	0.645	29%	0.292	S	S	*	.	H	α-helix	trans	-71.8	-25.3	-177.2	0	0	0	0	0	114.3	R111 I113	R111-A115 WeakPolarHBondContact O-CB 3.28Å; R111-A115 PolarHBondContact O-N 3.31Å; I113-A115 PolarHBondContact O-N 2.98Å
116	S	86.2	Confident	92.3	Very high	18 Å²	18	53.7 Å²	53.7	13%	0.126	28%	0.284	C	S	.	.	S	Bend	trans	-66.7	142.4	174.6	62.6	0	0	0	0	111.4	K50 N54 N97 I113 Q114 V120	K50-S116 WeakPolarHBondContact CE-O 3.21Å; K50-S116 WeakPolarHBondContact CE-OG 3.37Å; K50-S116 PolarHBondContact NZ-O 2.65Å; N54-S116 PolarHBondContact OD1-O 3.04Å; N97-S116 WeakPolarHBondContact ND2-CB 3.47Å; I113-S116 PolarHBondContact O-N 3.45Å; I113-S116 PolarHBondContact O-OG 3.44Å; Q114-S116 PolarHBondContact O-N 3.04Å; S116-V120 WeakPolarHBondContact OG-CG2 3.43Å
117	K	85.1	Confident	92.3	Very high	194 Å²	194	47.1 Å²	47.1	84%	0.843	26%	0.26	S	S	*	.			trans	-106.5	137	179.2	-66.8	-174.5	178.4	-176.5	0	110	S119	K117-S119 VanDerWaalsContact C-N 3.33Å; K117-S119 PolarHBondContact O-N 3.39Å
118	G	88.1	Confident	91.9	Very high	45 Å²	45	48.2 Å²	48.2	46%	0.464	26%	0.257	S	S	.	.	S	Bend	trans	81.5	-64.1	175.9	0	0	0	0	0	114.1	Q49 K50	Q49-G118 PolarHBondContact OE1-O 3.28Å; K50-G118 WeakPolarHBondContact CB-O 3.43Å; K50-G118 PolarHBondContact N-O 3.26Å
119	S	92.4	Very high	91.1	Very high	43 Å²	43	46.5 Å²	46.5	30%	0.301	25%	0.253	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.3	157.8	-178.3	61.3	0	0	0	0	113.4	L48 K117	L48-S119 CarbonylContact O-C 3.57Å; L48-S119 VanDerWaalsContact O-CA 3.25Å; L48-S119 WeakPolarHBondContact O-CA 3.29Å; L48-S119 WeakPolarHBondContact O-CB 3.46Å; K117-S119 VanDerWaalsContact C-N 3.33Å; K117-S119 PolarHBondContact O-N 3.39Å
120	V	94.2	Very high	90.3	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	27%	0.27	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.2	125.6	178.4	-165	0	0	0	0	109	T47 L48 K50 I56 V96 I113 S116 I122	T47-V120 CarbonylContact C-O 3.5Å; T47-V120 WeakPolarHBondContact CA-O 3.3Å; L48-V120 PolarHBondContact N-O 2.88Å; L48-V120 PolarHBondContact O-N 3.48Å; K50-V120 HydrophobicContact CD-CG2 4.33Å; K50-V120 HydrophobicContact CG-CG2 4.2Å; I56-V120 HydrophobicContact CG2-CG2 4.09Å; V96-V120 HydrophobicContact CG1-CG1 3.85Å; I113-V120 HydrophobicContact CG1-CG1 4.37Å; I113-V120 HydrophobicContact CG2-CG1 4.34Å; I113-V120 HydrophobicContact CG2-CG2 4.26Å; S116-V120 WeakPolarHBondContact OG-CG2 3.43Å; V120-I122 HydrophobicContact CG1-CG1 4.06Å
121	T	95.3	Very high	89.1	Confident	35 Å²	35	51.4 Å²	51.4	22%	0.215	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.5	124.2	170.3	-55.9	0	0	0	0	109.8	V46 T47 V96 N97	V46-T121 CarbonylContact O-C 3.55Å; V46-T121 WeakPolarHBondContact O-CA 3.46Å; T47-T121 PolarHBondContact OG1-OG1 3.06Å; V96-T121 CarbonylContact C-O 3.56Å; V96-T121 WeakPolarHBondContact CA-O 3.37Å; N97-T121 PolarHBondContact N-O 2.88Å; N97-T121 PolarHBondContact OD1-N 3.39Å
122	I	96	Very high	88.2	Confident	1 Å²	1	52.2 Å²	52.2	1%	0.005	29%	0.286	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.4	118.4	-178.8	-59.2	-179.1	0	0	0	108.1	S45 V46 L48 I56 I58 L87 I93 R95 V120	S45-I122 WeakPolarHBondContact CA-O 2.99Å; V46-I122 HydrophobicContact CG1-CB 4.24Å; V46-I122 PolarHBondContact N-O 3.33Å; V46-I122 PolarHBondContact O-N 3.35Å; L48-I122 HydrophobicContact CD1-CD1 4.34Å; I56-I122 HydrophobicContact CD1-CD1 3.79Å; I58-I122 HydrophobicContact CD1-CD1 4.24Å; L87-I122 HydrophobicContact CD1-CD1 4.19Å; I93-I122 HydrophobicContact CG2-CG2 4.12Å; R95-I122 WeakPolarHBondContact O-CA 3.47Å; V120-I122 HydrophobicContact CG1-CG1 4.06Å
123	D	96.8	Very high	87.3	Confident	31 Å²	31	53.2 Å²	53.2	17%	0.166	29%	0.29	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.8	126.8	166.3	-61.9	-9.6	0	0	0	107.8	A44 S45 V94 R95	A44-D123 WeakPolarHBondContact O-CA 3.46Å; S45-D123 VanDerWaalsContact CB-OD1 3.3Å; S45-D123 WeakPolarHBondContact CB-OD1 3.39Å; S45-D123 PolarHBondContact OG-OD1 3.11Å; V94-D123 PolarHBondContact N-O 3.27Å; R95-D123 HydrophobicContact CB-CB 3.83Å; R95-D123 WeakPolarHBondContact CD-OD2 3.39Å; R95-D123 HydrophobicContact CG-CB 4.12Å; R95-D123 PolarHBondContact N-O 2.61Å; R95-D123 VanDerWaalsContact N-O 3.09Å; R95-D123 IonicContact NH1-OD2 3.17Å; R95-D123 PolarHBondContact NH1-OD2 3.24Å; R95-D123 VanDerWaalsContact NH1-OD2 3.11Å; R95-D123 PolarHBondContact O-N 2.71Å
124	Y	95.9	Very high	86.5	Confident	17 Å²	17	52.8 Å²	52.8	7%	0.067	29%	0.288	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.8	154.1	-174.5	64.5	-82	0	0	0	112.3	S43 A44 V46 S86 L87 D91 E92 K126	S43-Y124 WeakPolarHBondContact CA-O 3.17Å; A44-Y124 HydrophobicContact CB-CE1 3.9Å; A44-Y124 HydrophobicContact CB-CE2 3.92Å; A44-Y124 PolarHBondContact N-O 3Å; A44-Y124 PolarHBondContact O-N 3.49Å; V46-Y124 HydrophobicContact CB-CE1 4Å; V46-Y124 HydrophobicContact CG1-CD1 4.08Å; V46-Y124 HydrophobicContact CG1-CE1 3.68Å; S86-Y124 PolarHBondContact O-OH 2.97Å; L87-Y124 HydrophobicContact CD2-CD1 3.42Å; L87-Y124 VanDerWaalsContact CD2-CD1 3.42Å; L87-Y124 HydrophobicContact CD2-CD2 3.94Å; L87-Y124 HydrophobicContact CD2-CE1 3.6Å; L87-Y124 HydrophobicContact CD2-CE2 4.08Å; L87-Y124 HydrophobicContact CD2-CG 3.61Å; D91-Y124 HydrophobicContact CB-CD2 4.28Å; E92-Y124 CarbonylContact O-C 3.51Å; E92-Y124 WeakPolarHBondContact O-CA 3.42Å; E92-Y124 VanDerWaalsContact O-CB 3.25Å; E92-Y124 WeakPolarHBondContact O-CB 3.29Å; Y124-K126 HydrophobicContact CE2-CB 4.33Å; Y124-K126 HydrophobicContact CE2-CD 3.82Å
125	N	94.2	Very high	86.1	Confident	26 Å²	26	52.8 Å²	52.8	14%	0.139	29%	0.287	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98	110.8	169	-69.6	-26.4	0	0	0	108.3	S43 E92 V94 L127	S43-N125 PolarHBondContact OG-OD1 3.41Å; E92-N125 HydrophobicContact CB-CB 4.22Å; E92-N125 PolarHBondContact N-O 3.02Å; E92-N125 VanDerWaalsContact N-O 3.07Å; E92-N125 PolarHBondContact O-N 3.46Å; E92-N125 PolarHBondContact OE2-ND2 2.94Å; V94-N125 HydrophobicContact CG2-CB 4.38Å; V94-N125 WeakPolarHBondContact CG2-ND2 3.49Å; N125-L127 PolarHBondContact O-N 3.44Å
126	K	93.3	Very high	85.8	Confident	28 Å²	28	51.4 Å²	51.4	12%	0.122	27%	0.27	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.8	127.9	175.8	-165	79.6	-173.5	171.6	0	109.6	T41 S42 S86 E88 D91 Y124	T41-K126 WeakPolarHBondContact CA-O 3.42Å; T41-K126 VanDerWaalsContact CB-O 3.29Å; T41-K126 WeakPolarHBondContact CB-O 3.44Å; S42-K126 PolarHBondContact N-O 2.74Å; S42-K126 WeakPolarHBondContact O-CB 3.39Å; S42-K126 PolarHBondContact O-N 2.95Å; S42-K126 WeakPolarHBondContact OG-CB 3.48Å; S86-K126 PolarHBondContact O-NZ 3.38Å; E88-K126 WeakPolarHBondContact OE2-CE 3.5Å; E88-K126 IonicContact OE2-NZ 3.74Å; E88-K126 PolarHBondContact OE2-NZ 2.97Å; D91-K126 WeakPolarHBondContact OD1-CA 3.49Å; D91-K126 WeakPolarHBondContact OD2-CD 3.29Å; D91-K126 IonicContact OD2-NZ 3.61Å; D91-K126 PolarHBondContact OD2-NZ 3.33Å; D91-K126 VanDerWaalsContact OD2-NZ 3.12Å; Y124-K126 HydrophobicContact CE2-CB 4.33Å; Y124-K126 HydrophobicContact CE2-CD 3.82Å
127	L	90.5	Very high	85.6	Confident	3 Å²	3	56.5 Å²	56.5	2%	0.016	30%	0.295	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.1	114.6	171.8	173.1	49.1	0	0	0	109.9	M39 D91 N125 A129 Y315 R318	M39-L127 HydrophobicContact CE-CB 4.41Å; M39-L127 HydrophobicContact CE-CD1 3.21Å; M39-L127 HydrophobicContact CE-CD2 3.72Å; M39-L127 HydrophobicContact CE-CG 3.94Å; M39-L127 HydrophobicContact CG-CD1 3.72Å; M39-L127 HydrophobicContact SD-CD1 4.14Å; D91-L127 PolarHBondContact OD1-N 3.06Å; N125-L127 PolarHBondContact O-N 3.44Å; L127-A129 PolarHBondContact O-N 3.25Å; L127-Y315 HydrophobicContact CD1-CE2 4.31Å; L127-R318 HydrophobicContact CD2-CB 4.01Å
128	H	85.2	Confident	85.6	Confident	93 Å²	93	49.2 Å²	49.2	43%	0.431	27%	0.266	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.2	93.8	165.7	-58.8	-64.1	0	0	0	109.1	T40 S42	T40-H128 WeakPolarHBondContact O-CB 3.47Å; T40-H128 PolarHBondContact O-CD2 3.06Å; T40-H128 PolarHBondContact O-N 3.09Å; T40-H128 WeakPolarHBondContact OG1-CB 3.3Å; S42-H128 PolarHBondContact OG-NE2 3.29Å
129	A	76.9	Confident	85.5	Confident	21 Å²	21	47.4 Å²	47.4	17%	0.174	25%	0.245	C	C	.	.			trans	-75.2	132.5	172.7	0	0	0	0	0	110.4	L127 P131 L319 R322	L127-A129 PolarHBondContact O-N 3.25Å; A129-P131 WeakPolarHBondContact O-CD 3.3Å; A129-L319 HydrophobicContact CB-CD1 3.36Å; A129-R322 HydrophobicContact CB-CB 4.16Å; A129-R322 HydrophobicContact CB-CG 3.54Å
130	D	76	Confident	85.2	Confident	67 Å²	67	49.2 Å²	49.2	36%	0.358	25%	0.254	S	S	.	.			trans	-82.9	116.4	159.1	-179.4	-3.7	0	0	0	108.1	K132 Q133	D130-K132 PolarHBondContact O-N 2.97Å; D130-K132 WeakPolarHBondContact OD1-CB 3.36Å; D130-K132 WeakPolarHBondContact OD1-CG 3.33Å; D130-K132 PolarHBondContact OD1-N 3Å; D130-Q133 HydrophobicContact CB-CG 4.02Å; D130-Q133 WeakPolarHBondContact O-CB 3.36Å; D130-Q133 PolarHBondContact O-N 3.46Å
131	P	68.5	Low	84.8	Confident	65 Å²	65	53.1 Å²	53.1	42%	0.422	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.9	-24.5	178.3	-25.4	34.3	0	0	0	113.7	A129 Q133 K135	A129-P131 WeakPolarHBondContact O-CD 3.3Å; P131-Q133 VanDerWaalsContact C-N 3.35Å; P131-K135 WeakPolarHBondContact O-CG 3.18Å
132	K	74	Confident	84.3	Confident	169 Å²	169	52 Å²	52	74%	0.735	27%	0.267	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.3	-35.7	177.1	-64.6	178.6	-178.9	176.4	0	112.3	D130 G134 K135	D130-K132 PolarHBondContact O-N 2.97Å; D130-K132 WeakPolarHBondContact OD1-CB 3.36Å; D130-K132 WeakPolarHBondContact OD1-CG 3.33Å; D130-K132 PolarHBondContact OD1-N 3Å; K132-G134 VanDerWaalsContact C-N 3.33Å; K132-K135 PolarHBondContact O-N 3.41Å
133	Q	73.8	Confident	83.8	Confident	68 Å²	68	54.1 Å²	54.1	32%	0.318	28%	0.276	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.9	-32.1	-179.2	-65.9	175.8	-8.4	0	0	111.8	F36 D130 P131 K135 L319	F36-Q133 HydrophobicContact CE2-CB 4.38Å; F36-Q133 HydrophobicContact CE2-CG 4.39Å; D130-Q133 HydrophobicContact CB-CG 4.02Å; D130-Q133 WeakPolarHBondContact O-CB 3.36Å; D130-Q133 PolarHBondContact O-N 3.46Å; P131-Q133 VanDerWaalsContact C-N 3.35Å; Q133-K135 PolarHBondContact O-N 3.05Å; Q133-L319 HydrophobicContact CB-CD2 3.79Å
134	G	75.2	Confident	83.2	Confident	2 Å²	2	56.9 Å²	56.9	2%	0.021	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-11.1	174.8	0	0	0	0	0	114.2	K132 T136 Y286	K132-G134 VanDerWaalsContact C-N 3.33Å; G134-T136 VanDerWaalsContact C-N 3.33Å; G134-T136 PolarHBondContact O-N 2.92Å; G134-Y286 WeakPolarHBondContact O-CE1 3.44Å; G134-Y286 PolarHBondContact O-OH 3.45Å
135	K	80.1	Confident	82.5	Confident	105 Å²	105	58 Å²	58	46%	0.457	30%	0.295	S	S	.	.			trans	-95	57.5	-179.1	-70.3	-177.6	178.4	-161.9	0	111.5	P131 K132 Q133 E282	P131-K135 WeakPolarHBondContact O-CG 3.18Å; K132-K135 PolarHBondContact O-N 3.41Å; Q133-K135 PolarHBondContact O-N 3.05Å; K135-E282 WeakPolarHBondContact CE-OE1 3.49Å; K135-E282 IonicContact NZ-OE1 2.71Å; K135-E282 PolarHBondContact NZ-OE1 3.32Å
136	T	83.3	Confident	81.9	Confident	48 Å²	48	57.1 Å²	57.1	29%	0.294	29%	0.291	S	S	.	.			trans	-63.2	158.4	175.3	64.8	0	0	0	0	111	G134 D138 I139 V140	G134-T136 VanDerWaalsContact C-N 3.33Å; G134-T136 PolarHBondContact O-N 2.92Å; T136-D138 PolarHBondContact O-N 2.9Å; T136-I139 PolarHBondContact O-N 3.35Å; T136-I139 WeakPolarHBondContact OG1-CG1 3.19Å; T136-I139 PolarHBondContact OG1-N 2.66Å; T136-V140 PolarHBondContact O-N 3.41Å; T136-V140 VanDerWaalsContact O-N 3.09Å
137	L	83.4	Confident	81.3	Confident	126 Å²	126	61 Å²	61	66%	0.66	31%	0.308	S	S	*	.	H	α-helix	trans	-54.6	-36.5	175.5	-70	174	0	0	0	111.7	V140 L141	L137-V140 WeakPolarHBondContact O-CB 3.47Å; L137-V140 PolarHBondContact O-N 3.14Å; L137-L141 VanDerWaalsContact O-CG 3.31Å; L137-L141 WeakPolarHBondContact O-CG 3.34Å; L137-L141 PolarHBondContact O-N 3.44Å
138	D	84.4	Confident	80.6	Confident	41 Å²	41	64.1 Å²	64.1	22%	0.219	32%	0.324	C	S	.	.	H	α-helix	trans	-58.9	-48.1	174.8	-177.6	34.8	0	0	0	112.2	T136 V140 L141 K142 K289	T136-D138 PolarHBondContact O-N 2.9Å; D138-V140 VanDerWaalsContact C-N 3.29Å; D138-V140 PolarHBondContact O-N 3.03Å; D138-L141 PolarHBondContact O-N 3.04Å; D138-K142 WeakPolarHBondContact O-CB 3.39Å; D138-K142 VanDerWaalsContact O-CG 3.3Å; D138-K142 WeakPolarHBondContact O-CG 3.35Å; D138-K142 PolarHBondContact O-N 2.91Å; D138-K142 WeakPolarHBondContact OD1-CE 3.46Å; D138-K142 WeakPolarHBondContact OD2-CE 3.3Å; D138-K289 VanDerWaalsContact OD2-CD 3.24Å; D138-K289 WeakPolarHBondContact OD2-CD 3.38Å; D138-K289 WeakPolarHBondContact OD2-CE 3.34Å; D138-K289 IonicContact OD2-NZ 3.28Å; D138-K289 PolarHBondContact OD2-NZ 2.91Å
139	I	86.1	Confident	80.2	Confident	6 Å²	6	59.9 Å²	59.9	3%	0.031	30%	0.304	C	S	.	.	H	α-helix	trans	-61.3	-38.5	175.5	-65.4	-63.2	0	0	0	111.5	T136 K143 Y286 K289 L320	T136-I139 PolarHBondContact O-N 3.35Å; T136-I139 WeakPolarHBondContact OG1-CG1 3.19Å; T136-I139 PolarHBondContact OG1-N 2.66Å; I139-K143 WeakPolarHBondContact O-CB 3.42Å; I139-K143 PolarHBondContact O-N 2.91Å; I139-Y286 HydrophobicContact CD1-CD1 3.76Å; I139-Y286 HydrophobicContact CD1-CE1 4.01Å; I139-Y286 HydrophobicContact CG1-CD1 4.31Å; I139-Y286 HydrophobicContact CG1-CE1 4.04Å; I139-Y286 HydrophobicContact CG2-CD1 4.4Å; I139-Y286 HydrophobicContact CG2-CE1 3.88Å; I139-K289 HydrophobicContact CD1-CB 3.65Å; I139-K289 HydrophobicContact CD1-CG 4.04Å; I139-L320 HydrophobicContact CD1-CD2 4.16Å; I139-L320 HydrophobicContact CG1-CD2 4.42Å
140	V	85.6	Confident	80	Confident	82 Å²	82	60.2 Å²	60.2	50%	0.497	30%	0.302	S	S	.	.	H	α-helix	trans	-66.1	-45.1	176.7	176.6	0	0	0	0	111.3	T136 L137 D138 K143 L144	T136-V140 PolarHBondContact O-N 3.41Å; T136-V140 VanDerWaalsContact O-N 3.09Å; L137-V140 WeakPolarHBondContact O-CB 3.47Å; L137-V140 PolarHBondContact O-N 3.14Å; D138-V140 VanDerWaalsContact C-N 3.29Å; D138-V140 PolarHBondContact O-N 3.03Å; V140-K143 PolarHBondContact O-N 3.49Å; V140-L144 PolarHBondContact O-N 3.27Å
141	L	85.7	Confident	79.7	Confident	81 Å²	81	63.2 Å²	63.2	42%	0.424	32%	0.318	S	S	.	.	H	α-helix	trans	-64.5	-41.6	177.3	-70.9	173.3	0	0	0	111.6	L137 D138 L144 K145	L137-L141 VanDerWaalsContact O-CG 3.31Å; L137-L141 WeakPolarHBondContact O-CG 3.34Å; L137-L141 PolarHBondContact O-N 3.44Å; D138-L141 PolarHBondContact O-N 3.04Å; L141-L144 WeakPolarHBondContact O-CB 3.49Å; L141-L144 PolarHBondContact O-N 3Å; L141-K145 PolarHBondContact O-N 3.46Å
142	K	85.5	Confident	79.8	Confident	12 Å²	12	62 Å²	62	5%	0.052	31%	0.308	C	S	.	.	H	α-helix	trans	-62.2	-44	173.4	-72.3	167.5	-173.8	-101.2	0	112	D138 L144 K145 H146 L288 K289 E292	D138-K142 WeakPolarHBondContact O-CB 3.39Å; D138-K142 VanDerWaalsContact O-CG 3.3Å; D138-K142 WeakPolarHBondContact O-CG 3.35Å; D138-K142 PolarHBondContact O-N 2.91Å; D138-K142 WeakPolarHBondContact OD1-CE 3.46Å; D138-K142 WeakPolarHBondContact OD2-CE 3.3Å; K142-L144 VanDerWaalsContact C-N 3.29Å; K142-L144 PolarHBondContact O-N 2.64Å; K142-K145 WeakPolarHBondContact O-CB 3.37Å; K142-K145 PolarHBondContact O-N 3.16Å; K142-H146 PolarHBondContact O-CD2 3.37Å; K142-H146 PolarHBondContact O-N 3.05Å; K142-L288 HydrophobicContact CD-CD2 4.32Å; K142-L288 HydrophobicContact CG-CD2 4.19Å; K142-K289 HydrophobicContact CD-CB 4.4Å; K142-E292 IonicContact NZ-OE1 2.69Å; K142-E292 PolarHBondContact NZ-OE1 3.3Å; K142-E292 IonicContact NZ-OE2 3.94Å; K142-E292 PolarHBondContact NZ-OE2 2.88Å
143	K	85.5	Confident	79.7	Confident	45 Å²	45	57.1 Å²	57.1	20%	0.196	30%	0.295	C	S	.	.	H	α-helix	trans	-59.5	-41.9	175.1	-172.3	-176.9	-179.6	-179.4	0	111.2	I139 V140 H146 K147 D278 F281 E282	I139-K143 WeakPolarHBondContact O-CB 3.42Å; I139-K143 PolarHBondContact O-N 2.91Å; V140-K143 PolarHBondContact O-N 3.49Å; K143-H146 PolarHBondContact O-N 3.34Å; K143-K147 WeakPolarHBondContact O-CB 3.31Å; K143-K147 PolarHBondContact O-N 3.41Å; K143-D278 VanDerWaalsContact CE-O 3.29Å; K143-D278 WeakPolarHBondContact CE-O 3.04Å; K143-D278 WeakPolarHBondContact CE-OD1 3.45Å; K143-D278 IonicContact NZ-OD1 3.05Å; K143-D278 PolarHBondContact NZ-OD1 3.4Å; K143-D278 IonicContact NZ-OD2 2.64Å; K143-D278 PolarHBondContact NZ-OD2 3.47Å; K143-F281 HydrophobicContact CG-CB 3.81Å; K143-E282 HydrophobicContact CD-CB 4.32Å
144	L	83.7	Confident	79.4	Confident	90 Å²	90	56.8 Å²	56.8	47%	0.471	30%	0.3	S	S	.	.	H	α-helix	trans	-64	-44.5	174.9	179.8	62	0	0	0	111.7	V140 L141 K142 H146 K147 I148	V140-L144 PolarHBondContact O-N 3.27Å; L141-L144 WeakPolarHBondContact O-CB 3.49Å; L141-L144 PolarHBondContact O-N 3Å; K142-L144 VanDerWaalsContact C-N 3.29Å; K142-L144 PolarHBondContact O-N 2.64Å; L144-H146 PolarHBondContact O-N 3.35Å; L144-K147 WeakPolarHBondContact O-CB 3.15Å; L144-K147 PolarHBondContact O-N 3.02Å; L144-I148 HydrophobicContact CD1-CD1 4.05Å; L144-I148 HydrophobicContact CD1-CG1 4.25Å; L144-I148 HydrophobicContact CG-CD1 3.93Å; L144-I148 WeakPolarHBondContact O-CG1 3.34Å; L144-I148 PolarHBondContact O-N 3.11Å
145	K	81.4	Confident	79.4	Confident	39 Å²	39	62.8 Å²	62.8	17%	0.17	33%	0.331	C	S	.	.	H	α-helix	trans	-54.3	-52.5	173.7	-179.6	-175.7	175.8	-180	0	110.5	L141 K142 K147 I148 V149	L141-K145 PolarHBondContact O-N 3.46Å; K142-K145 WeakPolarHBondContact O-CB 3.37Å; K142-K145 PolarHBondContact O-N 3.16Å; K145-K147 VanDerWaalsContact C-N 3.31Å; K145-K147 PolarHBondContact O-N 2.89Å; K145-I148 PolarHBondContact O-N 3.36Å; K145-V149 HydrophobicContact CG-CG2 4.16Å; K145-V149 VanDerWaalsContact O-CB 3.3Å; K145-V149 WeakPolarHBondContact O-CB 3.4Å; K145-V149 WeakPolarHBondContact O-CG2 3.37Å; K145-V149 PolarHBondContact O-N 2.94Å
146	H	81.2	Confident	79.1	Confident	9 Å²	9	61 Å²	61	4%	0.042	33%	0.33	C	S	.	.	H	α-helix	trans	-57.3	-44.2	177.7	-68.7	-56.6	0	0	0	112.3	K142 K143 L144 I148 V149 E150 F281	K142-H146 PolarHBondContact O-CD2 3.37Å; K142-H146 PolarHBondContact O-N 3.05Å; K143-H146 PolarHBondContact O-N 3.34Å; L144-H146 PolarHBondContact O-N 3.35Å; H146-I148 VanDerWaalsContact C-N 3.33Å; H146-I148 PolarHBondContact O-N 3.07Å; H146-V149 PolarHBondContact O-N 3.31Å; H146-E150 WeakPolarHBondContact O-CB 3.48Å; H146-E150 PolarHBondContact O-N 2.95Å; H146-F281 HydrophobicContact CB-CB 4.13Å; H146-F281 HydrophobicContact CB-CD1 3.58Å; H146-F281 HydrophobicContact CB-CE1 4.28Å; H146-F281 HydrophobicContact CB-CG 4.06Å
147	K	80.9	Confident	78.5	Confident	110 Å²	110	58.7 Å²	58.7	48%	0.478	32%	0.316	S	S	.	.	H	α-helix	trans	-61.3	-39	178.4	-173.3	177.8	-178.4	179.8	0	113.2	K143 L144 K145 N151 F281	K143-K147 WeakPolarHBondContact O-CB 3.31Å; K143-K147 PolarHBondContact O-N 3.41Å; L144-K147 WeakPolarHBondContact O-CB 3.15Å; L144-K147 PolarHBondContact O-N 3.02Å; K145-K147 VanDerWaalsContact C-N 3.31Å; K145-K147 PolarHBondContact O-N 2.89Å; K147-N151 PolarHBondContact O-ND2 3.1Å; K147-F281 HydrophobicContact CB-CD2 3.94Å; K147-F281 HydrophobicContact CB-CE2 3.97Å; K147-F281 HydrophobicContact CG-CD2 4.28Å; K147-F281 HydrophobicContact CG-CE2 4.01Å
148	I	77.2	Confident	77.9	Confident	68 Å²	68	56.6 Å²	56.6	35%	0.349	31%	0.305	S	S	.	.	H	α-helix	trans	-70.9	-48	178.1	-67.7	169.3	0	0	0	109.9	L144 K145 H146 E150 N151 I152 M162	L144-I148 HydrophobicContact CD1-CD1 4.05Å; L144-I148 HydrophobicContact CD1-CG1 4.25Å; L144-I148 HydrophobicContact CG-CD1 3.93Å; L144-I148 WeakPolarHBondContact O-CG1 3.34Å; L144-I148 PolarHBondContact O-N 3.11Å; K145-I148 PolarHBondContact O-N 3.36Å; H146-I148 VanDerWaalsContact C-N 3.33Å; H146-I148 PolarHBondContact O-N 3.07Å; I148-E150 VanDerWaalsContact C-N 3.26Å; I148-E150 PolarHBondContact O-N 3.37Å; I148-N151 PolarHBondContact O-N 3.48Å; I148-N151 VanDerWaalsContact O-N 3.08Å; I148-I152 HydrophobicContact CG2-CD1 3.53Å; I148-I152 HydrophobicContact CG2-CG1 4.45Å; I148-I152 WeakPolarHBondContact O-CG1 3.24Å; I148-I152 PolarHBondContact O-N 3.15Å; I148-M162 HydrophobicContact CG2-CE 3.58Å; I148-M162 HydrophobicContact CG2-SD 4.22Å
149	V	76.1	Confident	77.4	Confident	4 Å²	4	58.8 Å²	58.8	2%	0.024	33%	0.329	C	S	.	.	H	α-helix	trans	-65.1	-27.6	-176.4	172.3	0	0	0	0	113.1	K145 H146 N151 M162 R164	K145-V149 HydrophobicContact CG-CG2 4.16Å; K145-V149 VanDerWaalsContact O-CB 3.3Å; K145-V149 WeakPolarHBondContact O-CB 3.4Å; K145-V149 WeakPolarHBondContact O-CG2 3.37Å; K145-V149 PolarHBondContact O-N 2.94Å; H146-V149 PolarHBondContact O-N 3.31Å; V149-N151 VanDerWaalsContact C-N 3.35Å; V149-M162 HydrophobicContact CG2-CB 3.4Å; V149-M162 HydrophobicContact CG2-CE 4.17Å; V149-M162 HydrophobicContact CG2-CG 4.17Å; V149-M162 HydrophobicContact CG2-SD 3.78Å; V149-R164 HydrophobicContact CG1-CB 4.02Å; V149-R164 HydrophobicContact CG1-CG 3.47Å; V149-R164 VanDerWaalsContact CG1-CG 3.47Å; V149-R164 PolarHBondContact O-NE 3.42Å; V149-R164 PolarHBondContact O-NH2 2.94Å
150	E	73.3	Confident	76.8	Confident	27 Å²	27	63.5 Å²	63.5	13%	0.126	35%	0.354	C	S	.	.	H	α-helix	trans	-69.4	-32.2	174.1	-153.2	94.3	162.6	0	0	112.3	H146 I148 R164 V173 K280 F281	H146-E150 WeakPolarHBondContact O-CB 3.48Å; H146-E150 PolarHBondContact O-N 2.95Å; I148-E150 VanDerWaalsContact C-N 3.26Å; I148-E150 PolarHBondContact O-N 3.37Å; E150-R164 PolarHBondContact O-NH2 3.34Å; E150-V173 HydrophobicContact CG-CG2 4.32Å; E150-K280 IonicContact OE1-NZ 3.34Å; E150-K280 PolarHBondContact OE1-NZ 3.43Å; E150-F281 HydrophobicContact CB-CE1 3.78Å; E150-F281 HydrophobicContact CB-CZ 3.57Å; E150-F281 HydrophobicContact CG-CE1 3.9Å; E150-F281 HydrophobicContact CG-CZ 3.74Å; E150-F281 WeakPolarHBondContact OE2-CE1 3.4Å
151	N	69.3	Low	76	Confident	131 Å²	131	60.9 Å²	60.9	70%	0.701	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.8	-1.5	-176.6	-65.4	-28.2	0	0	0	113.8	K147 I148 V149	K147-N151 PolarHBondContact O-ND2 3.1Å; I148-N151 PolarHBondContact O-N 3.48Å; I148-N151 VanDerWaalsContact O-N 3.08Å; V149-N151 VanDerWaalsContact C-N 3.35Å
152	I	70.5	Confident	75	Confident	40 Å²	40	58.5 Å²	58.5	21%	0.205	33%	0.33	C	S	.	.	S	Bend	trans	-111.7	145	-177.1	-64.6	177.5	0	0	0	109	I148 T156 A157 L160 M162 R164	I148-I152 HydrophobicContact CG2-CD1 3.53Å; I148-I152 HydrophobicContact CG2-CG1 4.45Å; I148-I152 WeakPolarHBondContact O-CG1 3.24Å; I148-I152 PolarHBondContact O-N 3.15Å; I152-T156 VanDerWaalsContact CG2-CB 3.41Å; I152-T156 HydrophobicContact CG2-CG2 3.46Å; I152-T156 VanDerWaalsContact CG2-CG2 3.46Å; I152-A157 HydrophobicContact CG2-CB 4.19Å; I152-L160 HydrophobicContact CD1-CD1 4.24Å; I152-M162 HydrophobicContact CD1-CE 3.94Å; I152-R164 PolarHBondContact O-NH2 3.17Å
153	S	70.6	Confident	73.7	Confident	66 Å²	66	59 Å²	59	46%	0.462	34%	0.335	S	S	.	.			trans	-60.5	153.1	174.1	64.5	0	0	0	0	111.2	D155 T156 A157	S153-D155 VanDerWaalsContact C-N 3.3Å; S153-D155 PolarHBondContact O-N 3.08Å; S153-T156 PolarHBondContact O-N 3.04Å; S153-T156 WeakPolarHBondContact OG-CB 3.17Å; S153-T156 PolarHBondContact OG-N 3.29Å; S153-T156 PolarHBondContact OG-OG1 3.28Å; S153-A157 WeakPolarHBondContact O-CB 3.31Å; S153-A157 PolarHBondContact O-N 3.42Å
154	S	69.2	Low	72.4	Confident	60 Å²	60	61 Å²	61	42%	0.42	34%	0.342	S	S	.	.	H	α-helix	trans	-51.9	-51.1	179.3	-166.4	0	0	0	0	111.3	T156 A157 D158	S154-T156 VanDerWaalsContact C-N 3.31Å; S154-T156 PolarHBondContact O-N 3.39Å; S154-A157 WeakPolarHBondContact O-CB 3.43Å; S154-A157 PolarHBondContact O-N 3.37Å; S154-A157 VanDerWaalsContact O-N 3.13Å; S154-D158 VanDerWaalsContact O-CG 3.31Å; S154-D158 PolarHBondContact O-N 3.27Å; S154-D158 PolarHBondContact OG-OD2 3.14Å
155	D	74.3	Confident	71.1	Confident	128 Å²	128	57.9 Å²	57.9	68%	0.684	33%	0.328	S	S	*	.	H	α-helix	trans	-61.1	-39.2	-176.3	-53.9	-20.9	0	0	0	112.5	S153 A159	S153-D155 VanDerWaalsContact C-N 3.3Å; S153-D155 PolarHBondContact O-N 3.08Å; D155-A159 VanDerWaalsContact O-CB 3.29Å; D155-A159 WeakPolarHBondContact O-CB 3.38Å; D155-A159 PolarHBondContact O-N 3.22Å
156	T	73.2	Confident	69.6	Low	68 Å²	68	62.1 Å²	62.1	42%	0.417	35%	0.351	S	S	.	.	H	α-helix	trans	-74.7	-36.6	178.3	-58.8	0	0	0	0	111.3	I152 S153 S154 D158 A159 L160	I152-T156 VanDerWaalsContact CG2-CB 3.41Å; I152-T156 HydrophobicContact CG2-CG2 3.46Å; I152-T156 VanDerWaalsContact CG2-CG2 3.46Å; S153-T156 PolarHBondContact O-N 3.04Å; S153-T156 WeakPolarHBondContact OG-CB 3.17Å; S153-T156 PolarHBondContact OG-N 3.29Å; S153-T156 PolarHBondContact OG-OG1 3.28Å; S154-T156 VanDerWaalsContact C-N 3.31Å; S154-T156 PolarHBondContact O-N 3.39Å; T156-D158 VanDerWaalsContact C-N 3.34Å; T156-A159 PolarHBondContact O-N 2.92Å; T156-L160 HydrophobicContact CG2-CD1 4.11Å; T156-L160 WeakPolarHBondContact O-CB 3.46Å; T156-L160 VanDerWaalsContact O-CG 3.27Å; T156-L160 WeakPolarHBondContact O-CG 3.44Å; T156-L160 PolarHBondContact O-N 2.89Å
157	A	70.4	Confident	68.1	Low	0 Å²	0	63.5 Å²	63.5	0%	0	36%	0.359	C	S	.	.	H	α-helix	trans	-63.3	-43.7	175.4	0	0	0	0	0	110.6	I152 S153 S154 L160 G161 M162	I152-A157 HydrophobicContact CG2-CB 4.19Å; S153-A157 WeakPolarHBondContact O-CB 3.31Å; S153-A157 PolarHBondContact O-N 3.42Å; S154-A157 WeakPolarHBondContact O-CB 3.43Å; S154-A157 PolarHBondContact O-N 3.37Å; S154-A157 VanDerWaalsContact O-N 3.13Å; A157-L160 CarbonylContact O-C 2.97Å; A157-L160 PolarHBondContact O-N 3.41Å; A157-G161 PolarHBondContact O-N 2.83Å; A157-M162 WeakPolarHBondContact CB-O 3.48Å; A157-M162 CarbonylContact O-C 3.53Å; A157-M162 WeakPolarHBondContact O-CA 3.3Å; A157-M162 PolarHBondContact O-N 3.32Å
158	D	72.8	Confident	66.3	Low	81 Å²	81	60.9 Å²	60.9	43%	0.433	35%	0.354	S	S	.	.	H	α-helix	trans	-66.5	-41.2	176.2	-66.4	-34.6	0	0	0	111.9	S154 T156 L160 G161	S154-D158 VanDerWaalsContact O-CG 3.31Å; S154-D158 PolarHBondContact O-N 3.27Å; S154-D158 PolarHBondContact OG-OD2 3.14Å; T156-D158 VanDerWaalsContact C-N 3.34Å; D158-L160 PolarHBondContact O-N 3.49Å; D158-G161 PolarHBondContact O-N 2.93Å
159	A	73.4	Confident	64.9	Low	87 Å²	87	65.9 Å²	65.9	72%	0.719	38%	0.375	S	S	*	.	H	α-helix	trans	-61.8	-31.1	174.2	0	0	0	0	0	113.2	D155 T156 G161	D155-A159 VanDerWaalsContact O-CB 3.29Å; D155-A159 WeakPolarHBondContact O-CB 3.38Å; D155-A159 PolarHBondContact O-N 3.22Å; T156-A159 PolarHBondContact O-N 2.92Å; A159-G161 VanDerWaalsContact C-N 3.32Å
160	L	73	Confident	64.4	Low	106 Å²	106	66.8 Å²	66.8	56%	0.555	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.1	1.3	175.3	-67.3	174.5	0	0	0	113.3	I152 T156 A157 D158 M162	I152-L160 HydrophobicContact CD1-CD1 4.24Å; T156-L160 HydrophobicContact CG2-CD1 4.11Å; T156-L160 WeakPolarHBondContact O-CB 3.46Å; T156-L160 VanDerWaalsContact O-CG 3.27Å; T156-L160 WeakPolarHBondContact O-CG 3.44Å; T156-L160 PolarHBondContact O-N 2.89Å; A157-L160 CarbonylContact O-C 2.97Å; A157-L160 PolarHBondContact O-N 3.41Å; D158-L160 PolarHBondContact O-N 3.49Å; L160-M162 HydrophobicContact CB-CE 4.15Å; L160-M162 HydrophobicContact CB-CG 4.37Å; L160-M162 HydrophobicContact CD1-CE 3.84Å; L160-M162 PolarHBondContact O-N 3.1Å
161	G	67.9	Low	64.4	Low	27 Å²	27	67.3 Å²	67.3	28%	0.278	39%	0.393	S	S	.	.	T	Hydrogen-bonded Turn	trans	68.4	22.2	-175.3	0	0	0	0	0	113.4	L22 A157 D158 A159	L22-G161 WeakPolarHBondContact CD2-O 3.2Å; A157-G161 PolarHBondContact O-N 2.83Å; D158-G161 PolarHBondContact O-N 2.93Å; A159-G161 VanDerWaalsContact C-N 3.32Å
162	M	65.3	Low	64.7	Low	31 Å²	31	61.4 Å²	61.4	15%	0.153	36%	0.361	C	S	.	.			trans	-107.7	70.7	177.3	-59.8	-162.7	-73.8	0	0	111.3	I148 V149 I152 A157 L160 R164	I148-M162 HydrophobicContact CG2-CE 3.58Å; I148-M162 HydrophobicContact CG2-SD 4.22Å; V149-M162 HydrophobicContact CG2-CB 3.4Å; V149-M162 HydrophobicContact CG2-CE 4.17Å; V149-M162 HydrophobicContact CG2-CG 4.17Å; V149-M162 HydrophobicContact CG2-SD 3.78Å; I152-M162 HydrophobicContact CD1-CE 3.94Å; A157-M162 WeakPolarHBondContact CB-O 3.48Å; A157-M162 CarbonylContact O-C 3.53Å; A157-M162 WeakPolarHBondContact O-CA 3.3Å; A157-M162 PolarHBondContact O-N 3.32Å; L160-M162 HydrophobicContact CB-CE 4.15Å; L160-M162 HydrophobicContact CB-CG 4.37Å; L160-M162 HydrophobicContact CD1-CE 3.84Å; L160-M162 PolarHBondContact O-N 3.1Å; M162-R164 PolarHBondContact O-N 2.83Å
163	S	58.8	Low	64.8	Low	22 Å²	22	60.7 Å²	60.7	15%	0.154	36%	0.359	C	S	.	.			trans	-55.8	138.3	175	-56.4	0	0	0	0	111.9	W18 L22	W18-S163 VanDerWaalsContact CZ3-CB 3.48Å; L22-S163 VanDerWaalsContact CD1-OG 3.32Å; L22-S163 WeakPolarHBondContact CD1-OG 3.39Å
164	R	57.6	Low	65.2	Low	88 Å²	88	64.1 Å²	64.1	33%	0.332	37%	0.365	S	S	.	.			trans	-71	134.4	-178.5	-64.4	-171.2	127.6	-164.8	-0.3	111.3	V149 E150 I152 M162 I166	V149-R164 HydrophobicContact CG1-CB 4.02Å; V149-R164 HydrophobicContact CG1-CG 3.47Å; V149-R164 VanDerWaalsContact CG1-CG 3.47Å; V149-R164 PolarHBondContact O-NE 3.42Å; V149-R164 PolarHBondContact O-NH2 2.94Å; E150-R164 PolarHBondContact O-NH2 3.34Å; I152-R164 PolarHBondContact O-NH2 3.17Å; M162-R164 PolarHBondContact O-N 2.83Å; R164-I166 HydrophobicContact CB-CG1 4.03Å; R164-I166 PolarHBondContact O-N 2.96Å
165	A	56	Low	65.6	Low	23 Å²	23	67.9 Å²	67.9	19%	0.19	37%	0.37	C	S	.	.			trans	-78.5	100	155.4	0	0	0	0	0	107.4	L167 L284	A165-L167 PolarHBondContact O-N 3.4Å; A165-L284 HydrophobicContact CB-CD1 4.39Å; A165-L284 HydrophobicContact CB-CD2 4.47Å
166	I	49.9	Very low	65.6	Low	128 Å²	128	62.7 Å²	62.7	66%	0.656	34%	0.342	S	S	*	.			trans	-79.4	105.5	176.5	-56	173.8	0	0	0	106.9	R164 C168	R164-I166 HydrophobicContact CB-CG1 4.03Å; R164-I166 PolarHBondContact O-N 2.96Å; I166-C168 PolarHBondContact O-N 3.41Å
167	L	51.4	Low	66	Low	38 Å²	38	64.8 Å²	64.8	20%	0.199	35%	0.348	C	S	.	.			trans	-69.3	104.9	152.3	-99.6	153.3	0	0	0	105.5	A165 H169 D170 K280 L284	A165-L167 PolarHBondContact O-N 3.4Å; L167-H169 PolarHBondContact O-N 3.25Å; L167-D170 PolarHBondContact O-N 3.41Å; L167-K280 HydrophobicContact CD1-CD 4.07Å; L167-K280 VanDerWaalsContact CD1-CE 3.45Å; L167-K280 HydrophobicContact CD1-CG 3.66Å; L167-L284 HydrophobicContact CD1-CD1 3.91Å; L167-L284 HydrophobicContact CD1-CD2 3.5Å; L167-L284 VanDerWaalsContact CD1-CD2 3.5Å; L167-L284 HydrophobicContact CD1-CG 3.71Å; L167-L284 HydrophobicContact CG-CD2 3.83Å
168	C	42.5	Very low	66.6	Low	55 Å²	55	68.4 Å²	68.4	37%	0.372	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-47.4	131.9	174.5	-63.5	0	0	0	0	108.9	I166 D170	I166-C168 PolarHBondContact O-N 3.41Å; C168-D170 PolarHBondContact O-N 3.45Å
169	H	48.2	Very low	66.9	Low	173 Å²	173	65.4 Å²	65.4	80%	0.801	35%	0.351	S	S	*	.	T	Hydrogen-bonded Turn	trans	70.2	17.5	173.1	-56.1	-73.2	0	0	0	119.5	L167 G171	L167-H169 PolarHBondContact O-N 3.25Å; H169-G171 PolarHBondContact O-N 3.37Å
170	D	65.2	Low	67.4	Low	23 Å²	23	65.6 Å²	65.6	12%	0.123	34%	0.337	C	S	.	.			trans	-76	74.7	170.3	-165.6	13	0	0	0	112.9	L167 C168 L172 Y276 K280	L167-D170 PolarHBondContact O-N 3.41Å; C168-D170 PolarHBondContact O-N 3.45Å; D170-L172 PolarHBondContact O-N 2.98Å; D170-L172 VanDerWaalsContact O-N 3.14Å; D170-L172 WeakPolarHBondContact OD1-CB 3.44Å; D170-L172 WeakPolarHBondContact OD1-CG 3.45Å; D170-L172 PolarHBondContact OD1-N 2.86Å; D170-Y276 PolarHBondContact OD1-OH 3.38Å; D170-Y276 VanDerWaalsContact OD1-OH 3.1Å; D170-Y276 WeakPolarHBondContact OD2-CE1 3.48Å; D170-Y276 PolarHBondContact OD2-OH 3.19Å; D170-K280 VanDerWaalsContact OD2-CD 3.25Å; D170-K280 WeakPolarHBondContact OD2-CD 3.45Å; D170-K280 VanDerWaalsContact OD2-CE 3.28Å; D170-K280 WeakPolarHBondContact OD2-CE 3.27Å; D170-K280 IonicContact OD2-NZ 2.74Å; D170-K280 PolarHBondContact OD2-NZ 2.96Å
171	G	72.1	Confident	67.9	Low	39 Å²	39	67.8 Å²	67.8	40%	0.402	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.5	-2.2	174.2	0	0	0	0	0	114.1	H169 V173 K174 R175	H169-G171 PolarHBondContact O-N 3.37Å; G171-V173 VanDerWaalsContact C-N 3.33Å; G171-V173 PolarHBondContact O-N 3.49Å; G171-K174 PolarHBondContact O-N 2.8Å; G171-R175 WeakPolarHBondContact O-CG 3.45Å; G171-R175 PolarHBondContact O-N 3.46Å
172	L	76.9	Confident	68.6	Low	6 Å²	6	69.4 Å²	69.4	3%	0.031	34%	0.344	C	S	.	.	H	α-helix	trans	-68	-31.9	180	-67.3	176.2	0	0	0	112.7	D170 R175 L176 L273 Y276 R335 V338 L339 L342	D170-L172 PolarHBondContact O-N 2.98Å; D170-L172 VanDerWaalsContact O-N 3.14Å; D170-L172 WeakPolarHBondContact OD1-CB 3.44Å; D170-L172 WeakPolarHBondContact OD1-CG 3.45Å; D170-L172 PolarHBondContact OD1-N 2.86Å; L172-R175 PolarHBondContact O-N 2.69Å; L172-L176 PolarHBondContact O-N 2.79Å; L172-L273 HydrophobicContact CB-CD1 4.05Å; L172-Y276 HydrophobicContact CB-CE1 4.09Å; L172-Y276 HydrophobicContact CD1-CD1 4.02Å; L172-Y276 HydrophobicContact CD1-CE1 3.49Å; L172-Y276 VanDerWaalsContact CD1-CE1 3.49Å; L172-Y276 HydrophobicContact CD1-CE2 4.16Å; L172-Y276 HydrophobicContact CG-CE1 4.41Å; L172-R335 HydrophobicContact CD1-CG 4Å; L172-V338 HydrophobicContact CD1-CG1 3.94Å; L172-V338 HydrophobicContact CD2-CG1 3.78Å; L172-V338 HydrophobicContact CG-CG1 4.41Å; L172-L339 HydrophobicContact CD2-CD2 3.74Å; L172-L339 HydrophobicContact CD2-CG 4.29Å; L172-L342 HydrophobicContact CD2-CD1 3.83Å
173	V	72.5	Confident	69.5	Low	25 Å²	25	69 Å²	69	15%	0.152	34%	0.343	C	S	.	.	H	α-helix	trans	-64.3	-47.7	174.1	178.3	0	0	0	0	110.1	E150 G171 R175 L176 E177 L277	E150-V173 HydrophobicContact CG-CG2 4.32Å; G171-V173 VanDerWaalsContact C-N 3.33Å; G171-V173 PolarHBondContact O-N 3.49Å; V173-R175 VanDerWaalsContact C-N 3.32Å; V173-R175 PolarHBondContact O-N 3.07Å; V173-L176 WeakPolarHBondContact O-CA 3.46Å; V173-L176 WeakPolarHBondContact O-CB 3.05Å; V173-L176 PolarHBondContact O-N 2.82Å; V173-E177 PolarHBondContact O-N 2.98Å; V173-L277 HydrophobicContact CG2-CD2 3.7Å
174	K	77.7	Confident	70.7	Confident	138 Å²	138	70 Å²	70	60%	0.6	36%	0.357	S	S	*	.	H	α-helix	trans	-60.5	-42	175.2	-174.2	176.4	175	178.2	0	111.8	G171 L176 E177 D178	G171-K174 PolarHBondContact O-N 2.8Å; K174-L176 PolarHBondContact O-N 3.35Å; K174-E177 PolarHBondContact O-N 3.26Å; K174-D178 WeakPolarHBondContact O-CB 3.37Å; K174-D178 VanDerWaalsContact O-CG 3.32Å; K174-D178 PolarHBondContact O-N 3.46Å
175	R	78	Confident	72	Confident	140 Å²	140	70.3 Å²	70.3	53%	0.528	37%	0.369	S	S	.	.	H	α-helix	trans	-62.5	-30	173.8	-72.2	-174.8	-177	-169.5	1.4	112.7	G171 L172 V173 L179 L342	G171-R175 WeakPolarHBondContact O-CG 3.45Å; G171-R175 PolarHBondContact O-N 3.46Å; L172-R175 PolarHBondContact O-N 2.69Å; V173-R175 VanDerWaalsContact C-N 3.32Å; V173-R175 PolarHBondContact O-N 3.07Å; R175-L179 VanDerWaalsContact O-CB 3.25Å; R175-L179 WeakPolarHBondContact O-CB 3.09Å; R175-L179 PolarHBondContact O-N 2.87Å; R175-L342 HydrophobicContact CB-CD1 4.28Å
176	L	75.6	Confident	73.2	Confident	18 Å²	18	70.3 Å²	70.3	9%	0.094	36%	0.364	C	S	.	.	H	α-helix	trans	-66.4	-50	171.4	-172.8	50.2	0	0	0	111.4	L172 V173 K174 D178 L179 E180 R270 L273 L277	L172-L176 PolarHBondContact O-N 2.79Å; V173-L176 WeakPolarHBondContact O-CA 3.46Å; V173-L176 WeakPolarHBondContact O-CB 3.05Å; V173-L176 PolarHBondContact O-N 2.82Å; K174-L176 PolarHBondContact O-N 3.35Å; L176-D178 VanDerWaalsContact C-N 3.28Å; L176-D178 PolarHBondContact O-N 3.35Å; L176-L179 CarbonylContact O-C 3.43Å; L176-L179 WeakPolarHBondContact O-CA 3.39Å; L176-L179 WeakPolarHBondContact O-CB 3.21Å; L176-L179 PolarHBondContact O-N 3.28Å; L176-L179 VanDerWaalsContact O-N 3.09Å; L176-E180 HydrophobicContact CD1-CG 4.1Å; L176-E180 HydrophobicContact CG-CG 4.36Å; L176-E180 WeakPolarHBondContact O-CG 3.3Å; L176-E180 PolarHBondContact O-N 2.95Å; L176-R270 HydrophobicContact CD1-CG 4.25Å; L176-L273 HydrophobicContact CB-CD2 3.39Å; L176-L273 HydrophobicContact CD1-CD2 3.47Å; L176-L273 VanDerWaalsContact CD1-CD2 3.47Å; L176-L273 HydrophobicContact CD2-CD2 3.73Å; L176-L273 HydrophobicContact CD2-CG 4.42Å; L176-L273 HydrophobicContact CG-CD2 3.65Å; L176-L277 HydrophobicContact CD2-CD1 4.34Å
177	E	80.2	Confident	74.9	Confident	113 Å²	113	68 Å²	68	53%	0.528	35%	0.349	S	S	.	.	H	α-helix	trans	-59.4	-44.1	-179.4	-67.9	171.6	173.5	0	0	110.2	V173 K174 L179 E180 K181	V173-E177 PolarHBondContact O-N 2.98Å; K174-E177 PolarHBondContact O-N 3.26Å; E177-L179 VanDerWaalsContact C-N 3.35Å; E177-L179 PolarHBondContact O-N 3.1Å; E177-E180 PolarHBondContact O-N 3.27Å; E177-K181 VanDerWaalsContact O-CB 3.31Å; E177-K181 WeakPolarHBondContact O-CB 3.45Å; E177-K181 PolarHBondContact O-N 3.39Å
178	D	83.1	Confident	76.5	Confident	75 Å²	75	67.9 Å²	67.9	40%	0.401	36%	0.357	S	S	.	.	H	α-helix	trans	-61.5	-42.9	174.4	-69.9	-28.4	0	0	0	111.3	K174 L176 N182	K174-D178 WeakPolarHBondContact O-CB 3.37Å; K174-D178 VanDerWaalsContact O-CG 3.32Å; K174-D178 PolarHBondContact O-N 3.46Å; L176-D178 VanDerWaalsContact C-N 3.28Å; L176-D178 PolarHBondContact O-N 3.35Å; D178-N182 VanDerWaalsContact O-CB 3.28Å; D178-N182 WeakPolarHBondContact O-CB 3.42Å; D178-N182 PolarHBondContact O-N 3.07Å; D178-N182 PolarHBondContact O-ND2 3.04Å; D178-N182 VanDerWaalsContact O-ND2 3.11Å
179	L	80.8	Confident	78.5	Confident	19 Å²	19	68 Å²	68	10%	0.099	35%	0.354	C	S	.	.	H	α-helix	trans	-63.3	-43.7	175.6	177.7	63.9	0	0	0	112	R175 L176 E177 N182 T183 T269 L342 L345	R175-L179 VanDerWaalsContact O-CB 3.25Å; R175-L179 WeakPolarHBondContact O-CB 3.09Å; R175-L179 PolarHBondContact O-N 2.87Å; L176-L179 CarbonylContact O-C 3.43Å; L176-L179 WeakPolarHBondContact O-CA 3.39Å; L176-L179 WeakPolarHBondContact O-CB 3.21Å; L176-L179 PolarHBondContact O-N 3.28Å; L176-L179 VanDerWaalsContact O-N 3.09Å; E177-L179 VanDerWaalsContact C-N 3.35Å; E177-L179 PolarHBondContact O-N 3.1Å; L179-N182 PolarHBondContact O-N 2.71Å; L179-T183 WeakPolarHBondContact O-CB 3.29Å; L179-T183 PolarHBondContact O-N 2.92Å; L179-T183 PolarHBondContact O-OG1 3.04Å; L179-T269 HydrophobicContact CD2-CG2 4.15Å; L179-L342 HydrophobicContact CD2-CD2 4.07Å; L179-L345 HydrophobicContact CD1-CD2 3.59Å; L179-L345 HydrophobicContact CD2-CD2 4.04Å; L179-L345 HydrophobicContact CG-CD2 4.48Å
180	E	82.1	Confident	80.2	Confident	90 Å²	90	60 Å²	60	42%	0.421	32%	0.317	S	S	.	.	H	α-helix	trans	-67.8	-44	179.7	-74.8	-175.2	165.2	0	0	111.4	L176 E177 N182 T183 G184	L176-E180 HydrophobicContact CD1-CG 4.1Å; L176-E180 HydrophobicContact CG-CG 4.36Å; L176-E180 WeakPolarHBondContact O-CG 3.3Å; L176-E180 PolarHBondContact O-N 2.95Å; E177-E180 PolarHBondContact O-N 3.27Å; E180-N182 VanDerWaalsContact C-N 3.34Å; E180-N182 PolarHBondContact O-N 3.48Å; E180-T183 WeakPolarHBondContact O-CB 3.47Å; E180-T183 PolarHBondContact O-N 3.29Å; E180-G184 PolarHBondContact O-N 3.18Å
181	K	85.3	Confident	81.2	Confident	153 Å²	153	61 Å²	61	67%	0.665	32%	0.322	S	S	*	.	H	α-helix	trans	-58.1	-48.1	173.9	-175.5	-177.9	179.3	179.5	0	111.1	E177 T183 G184 V185	E177-K181 VanDerWaalsContact O-CB 3.31Å; E177-K181 WeakPolarHBondContact O-CB 3.45Å; E177-K181 PolarHBondContact O-N 3.39Å; K181-T183 VanDerWaalsContact C-N 3.33Å; K181-T183 PolarHBondContact O-N 2.94Å; K181-G184 PolarHBondContact O-N 3.32Å; K181-V185 PolarHBondContact O-N 3.25Å; K181-V185 VanDerWaalsContact O-N 3.1Å
182	N	81	Confident	82	Confident	60 Å²	60	64.2 Å²	64.2	32%	0.321	33%	0.327	S	S	.	.	H	α-helix	trans	-63.4	-41.1	177.8	-71	-21.7	0	0	0	111.4	D178 L179 E180 G184 V185 Y186	D178-N182 VanDerWaalsContact O-CB 3.28Å; D178-N182 WeakPolarHBondContact O-CB 3.42Å; D178-N182 PolarHBondContact O-N 3.07Å; D178-N182 PolarHBondContact O-ND2 3.04Å; D178-N182 VanDerWaalsContact O-ND2 3.11Å; L179-N182 PolarHBondContact O-N 2.71Å; E180-N182 VanDerWaalsContact C-N 3.34Å; E180-N182 PolarHBondContact O-N 3.48Å; N182-G184 VanDerWaalsContact C-N 3.28Å; N182-G184 PolarHBondContact O-N 3.06Å; N182-V185 PolarHBondContact O-N 3.25Å; N182-Y186 HydrophobicContact CB-CE2 4.05Å; N182-Y186 WeakPolarHBondContact O-CD2 3.46Å; N182-Y186 PolarHBondContact O-N 3.48Å
183	T	84.7	Confident	82.5	Confident	22 Å²	22	64.1 Å²	64.1	14%	0.135	33%	0.326	C	S	.	.	H	α-helix	trans	-58.1	-41.7	174	-58.1	0	0	0	0	111.4	L179 E180 K181 Y186 K187 L262 V266	L179-T183 WeakPolarHBondContact O-CB 3.29Å; L179-T183 PolarHBondContact O-N 2.92Å; L179-T183 PolarHBondContact O-OG1 3.04Å; E180-T183 WeakPolarHBondContact O-CB 3.47Å; E180-T183 PolarHBondContact O-N 3.29Å; K181-T183 VanDerWaalsContact C-N 3.33Å; K181-T183 PolarHBondContact O-N 2.94Å; T183-Y186 PolarHBondContact O-N 3.33Å; T183-K187 WeakPolarHBondContact O-CB 3.47Å; T183-K187 PolarHBondContact O-N 3.28Å; T183-L262 HydrophobicContact CG2-CD2 4.17Å; T183-V266 HydrophobicContact CG2-CG1 3.87Å; T183-V266 WeakPolarHBondContact OG1-CG1 2.97Å
184	G	85.1	Confident	83.2	Confident	44 Å²	44	63.2 Å²	63.2	45%	0.454	32%	0.322	S	S	.	.	H	α-helix	trans	-60.7	-43.9	175.2	0	0	0	0	0	112.8	E180 K181 N182 Y186 K187 G188	E180-G184 PolarHBondContact O-N 3.18Å; K181-G184 PolarHBondContact O-N 3.32Å; N182-G184 VanDerWaalsContact C-N 3.28Å; N182-G184 PolarHBondContact O-N 3.06Å; G184-Y186 VanDerWaalsContact C-N 3.35Å; G184-Y186 PolarHBondContact O-N 3.47Å; G184-K187 PolarHBondContact O-N 2.91Å; G184-G188 PolarHBondContact O-N 3.4Å
185	V	83.4	Confident	83.8	Confident	94 Å²	94	64.3 Å²	64.3	57%	0.57	32%	0.322	S	S	*	.	H	α-helix	trans	-60.9	-44.4	174.7	176.2	0	0	0	0	111.1	K181 N182 G188 L189	K181-V185 PolarHBondContact O-N 3.25Å; K181-V185 VanDerWaalsContact O-N 3.1Å; N182-V185 PolarHBondContact O-N 3.25Å; V185-G188 PolarHBondContact O-N 2.91Å; V185-L189 WeakPolarHBondContact O-CB 3.49Å; V185-L189 PolarHBondContact O-N 2.87Å
186	Y	81	Confident	84.3	Confident	24 Å²	24	60.3 Å²	60.3	9%	0.094	31%	0.311	C	S	.	.	H	α-helix	trans	-65.3	-39.6	178.2	-67.5	-50.6	0	0	0	112.9	N182 T183 G184 L189 M190 Y261 R349 L353	N182-Y186 HydrophobicContact CB-CE2 4.05Å; N182-Y186 WeakPolarHBondContact O-CD2 3.46Å; N182-Y186 PolarHBondContact O-N 3.48Å; T183-Y186 PolarHBondContact O-N 3.33Å; G184-Y186 VanDerWaalsContact C-N 3.35Å; G184-Y186 PolarHBondContact O-N 3.47Å; Y186-L189 PolarHBondContact O-N 3.05Å; Y186-M190 WeakPolarHBondContact O-CB 3.4Å; Y186-M190 WeakPolarHBondContact O-CG 3.47Å; Y186-M190 PolarHBondContact O-N 2.99Å; Y186-Y261 HydrophobicContact CD2-CE1 4.16Å; Y186-Y261 HydrophobicContact CE2-CE1 4.47Å; Y186-R349 HydrophobicContact CE2-CG 4.38Å; Y186-R349 PolarHBondContact OH-NH1 3.3Å; Y186-R349 VanDerWaalsContact OH-NH1 3.08Å; Y186-L353 HydrophobicContact CD1-CD1 3.69Å; Y186-L353 HydrophobicContact CD1-CD2 4.43Å; Y186-L353 HydrophobicContact CE1-CD1 3.4Å; Y186-L353 HydrophobicContact CE1-CD2 3.35Å; Y186-L353 HydrophobicContact CE1-CG 3.92Å
187	K	85.4	Confident	84.9	Confident	78 Å²	78	59.5 Å²	59.5	34%	0.339	31%	0.307	S	S	.	.	H	α-helix	trans	-60.5	-51.1	174.4	-169.7	-177.4	178.6	-168.3	0	110.5	T183 G184 L189 M190 D191 L430	T183-K187 WeakPolarHBondContact O-CB 3.47Å; T183-K187 PolarHBondContact O-N 3.28Å; G184-K187 PolarHBondContact O-N 2.91Å; K187-L189 VanDerWaalsContact C-N 3.32Å; K187-L189 PolarHBondContact O-N 3.07Å; K187-M190 WeakPolarHBondContact O-CB 3.49Å; K187-M190 PolarHBondContact O-N 3.03Å; K187-M190 VanDerWaalsContact O-N 3.09Å; K187-D191 PolarHBondContact O-N 3.3Å; K187-D191 VanDerWaalsContact O-OD1 3.11Å; K187-L430 WeakPolarHBondContact CE-O 3.46Å; K187-L430 PolarHBondContact NZ-O 3.2Å
188	G	86.8	Confident	85.3	Confident	36 Å²	36	59 Å²	59	37%	0.371	30%	0.303	S	S	.	.	H	α-helix	trans	-61.5	-36.8	178.2	0	0	0	0	0	113.9	G184 V185 D191 H192	G184-G188 PolarHBondContact O-N 3.4Å; V185-G188 PolarHBondContact O-N 2.91Å; G188-D191 PolarHBondContact O-N 2.97Å; G188-H192 PolarHBondContact O-N 2.73Å
189	L	84.2	Confident	85.6	Confident	57 Å²	57	58.9 Å²	58.9	30%	0.298	31%	0.308	S	S	.	.	H	α-helix	trans	-62.8	-46.4	172.5	175.9	65.9	0	0	0	111.3	V185 Y186 K187 D191 H192 I193 L357	V185-L189 WeakPolarHBondContact O-CB 3.49Å; V185-L189 PolarHBondContact O-N 2.87Å; Y186-L189 PolarHBondContact O-N 3.05Å; K187-L189 VanDerWaalsContact C-N 3.32Å; K187-L189 PolarHBondContact O-N 3.07Å; L189-D191 VanDerWaalsContact C-N 3.34Å; L189-D191 PolarHBondContact O-N 3.22Å; L189-H192 PolarHBondContact O-N 2.85Å; L189-I193 HydrophobicContact CD1-CD1 4.13Å; L189-I193 HydrophobicContact CD1-CG1 4.43Å; L189-I193 HydrophobicContact CG-CD1 4.03Å; L189-I193 WeakPolarHBondContact O-CG1 3.37Å; L189-I193 PolarHBondContact O-N 3.38Å; L189-L357 HydrophobicContact CD2-CD2 3.9Å
190	M	83.9	Confident	86	Confident	5 Å²	5	59 Å²	59	3%	0.025	31%	0.308	C	S	.	.	H	α-helix	trans	-63.4	-39	176.8	-77.5	-60.3	-67.1	0	0	112.3	Y186 K187 H192 I193 G194 I255 L258 L262 L430	Y186-M190 WeakPolarHBondContact O-CB 3.4Å; Y186-M190 WeakPolarHBondContact O-CG 3.47Å; Y186-M190 PolarHBondContact O-N 2.99Å; K187-M190 WeakPolarHBondContact O-CB 3.49Å; K187-M190 PolarHBondContact O-N 3.03Å; K187-M190 VanDerWaalsContact O-N 3.09Å; M190-H192 VanDerWaalsContact C-N 3.26Å; M190-H192 PolarHBondContact O-N 3.33Å; M190-I193 PolarHBondContact O-N 2.69Å; M190-G194 PolarHBondContact O-N 2.99Å; M190-I255 HydrophobicContact CE-CG2 4.35Å; M190-L258 HydrophobicContact CE-CB 3.88Å; M190-L258 HydrophobicContact CE-CD1 4.34Å; M190-L258 HydrophobicContact CG-CB 4.42Å; M190-L258 HydrophobicContact SD-CB 3.66Å; M190-L258 HydrophobicContact SD-CD1 3.37Å; M190-L258 WeakPolarHBondContact SD-CD1 3.4Å; M190-L258 HydrophobicContact SD-CG 4.1Å; M190-L262 HydrophobicContact CB-CD1 4.18Å; M190-L262 HydrophobicContact CG-CD1 3.63Å; M190-L430 HydrophobicContact CB-CD1 4.44Å; M190-L430 HydrophobicContact CB-CD2 4.21Å
191	D	86	Confident	86.3	Confident	45 Å²	45	55.2 Å²	55.2	24%	0.241	29%	0.291	C	S	.	.	H	α-helix	trans	-62	-38.1	175.3	-61.8	-10.9	0	0	0	111.2	K187 G188 L189 R195 L430	K187-D191 PolarHBondContact O-N 3.3Å; K187-D191 VanDerWaalsContact O-OD1 3.11Å; G188-D191 PolarHBondContact O-N 2.97Å; L189-D191 VanDerWaalsContact C-N 3.34Å; L189-D191 PolarHBondContact O-N 3.22Å; D191-R195 WeakPolarHBondContact O-CB 3.45Å; D191-R195 VanDerWaalsContact O-CG 3.3Å; D191-R195 WeakPolarHBondContact O-CG 3.25Å; D191-R195 PolarHBondContact O-N 3.34Å; D191-R195 PolarHBondContact O-NE 3.34Å; D191-L430 HydrophobicContact CB-CD1 4.45Å; D191-L430 WeakPolarHBondContact OD1-CB 3.49Å; D191-L430 WeakPolarHBondContact OD1-CD1 3.47Å; D191-L430 WeakPolarHBondContact OD1-CG 3.47Å
192	H	88.4	Confident	86.5	Confident	107 Å²	107	54.6 Å²	54.6	50%	0.495	29%	0.288	S	S	.	.	H	α-helix	trans	-70.7	-47.2	176.9	-172.1	64.4	0	0	0	112	G188 L189 M190 G194 R195 L196	G188-H192 PolarHBondContact O-N 2.73Å; L189-H192 PolarHBondContact O-N 2.85Å; M190-H192 VanDerWaalsContact C-N 3.26Å; M190-H192 PolarHBondContact O-N 3.33Å; H192-G194 VanDerWaalsContact C-N 3.33Å; H192-G194 PolarHBondContact O-N 3.06Å; H192-R195 PolarHBondContact O-N 3.46Å; H192-L196 WeakPolarHBondContact O-CB 3.34Å; H192-L196 PolarHBondContact O-N 2.94Å
193	I	87.6	Confident	87.1	Confident	4 Å²	4	54.9 Å²	54.9	2%	0.021	29%	0.289	C	S	.	.	H	α-helix	trans	-59	-47.1	175.8	-68.7	171.3	0	0	0	109.9	L189 M190 R195 L196 L197 F360	L189-I193 HydrophobicContact CD1-CD1 4.13Å; L189-I193 HydrophobicContact CD1-CG1 4.43Å; L189-I193 HydrophobicContact CG-CD1 4.03Å; L189-I193 WeakPolarHBondContact O-CG1 3.37Å; L189-I193 PolarHBondContact O-N 3.38Å; M190-I193 PolarHBondContact O-N 2.69Å; I193-R195 PolarHBondContact O-N 2.9Å; I193-L196 WeakPolarHBondContact O-CB 3.48Å; I193-L196 PolarHBondContact O-N 3.41Å; I193-L197 HydrophobicContact CG2-CD1 3.93Å; I193-L197 HydrophobicContact CG2-CG 4.28Å; I193-L197 VanDerWaalsContact O-CG 3.3Å; I193-L197 WeakPolarHBondContact O-CG 3.35Å; I193-L197 PolarHBondContact O-N 3.06Å; I193-F360 HydrophobicContact CB-CZ 4.46Å; I193-F360 HydrophobicContact CD1-CE1 4.5Å; I193-F360 HydrophobicContact CD1-CZ 4.49Å; I193-F360 HydrophobicContact CG1-CE1 4.18Å; I193-F360 HydrophobicContact CG1-CE2 4.23Å; I193-F360 HydrophobicContact CG1-CZ 3.88Å; I193-F360 HydrophobicContact CG2-CD2 4.26Å; I193-F360 HydrophobicContact CG2-CE2 3.71Å; I193-F360 HydrophobicContact CG2-CZ 4.13Å
194	G	87.3	Confident	87.4	Confident	6 Å²	6	54 Å²	54	6%	0.062	28%	0.284	C	S	.	.	H	α-helix	trans	-59	-43.8	177.7	0	0	0	0	0	112.7	M190 H192 L197 K198	M190-G194 PolarHBondContact O-N 2.99Å; H192-G194 VanDerWaalsContact C-N 3.33Å; H192-G194 PolarHBondContact O-N 3.06Å; G194-L197 PolarHBondContact O-N 3.44Å; G194-K198 VanDerWaalsContact O-CG 3.31Å; G194-K198 WeakPolarHBondContact O-CG 2.73Å; G194-K198 PolarHBondContact O-N 2.95Å
195	R	89	Confident	87.7	Confident	161 Å²	161	56.2 Å²	56.2	61%	0.608	28%	0.283	S	S	*	.	H	α-helix	trans	-64.1	-42	174.3	-77.8	-176.3	-67.3	156	-4.5	112.5	D191 H192 I193 L197 K198 S199	D191-R195 WeakPolarHBondContact O-CB 3.45Å; D191-R195 VanDerWaalsContact O-CG 3.3Å; D191-R195 WeakPolarHBondContact O-CG 3.25Å; D191-R195 PolarHBondContact O-N 3.34Å; D191-R195 PolarHBondContact O-NE 3.34Å; H192-R195 PolarHBondContact O-N 3.46Å; I193-R195 PolarHBondContact O-N 2.9Å; R195-L197 VanDerWaalsContact C-N 3.34Å; R195-K198 PolarHBondContact O-N 3.47Å; R195-S199 PolarHBondContact O-N 2.89Å
196	L	89.5	Confident	88.2	Confident	55 Å²	55	54.9 Å²	54.9	29%	0.288	28%	0.275	S	S	.	.	H	α-helix	trans	-61.4	-44.6	177.7	-175.8	69.3	0	0	0	111.1	H192 I193 S199 H200 F360 I364	H192-L196 WeakPolarHBondContact O-CB 3.34Å; H192-L196 PolarHBondContact O-N 2.94Å; I193-L196 WeakPolarHBondContact O-CB 3.48Å; I193-L196 PolarHBondContact O-N 3.41Å; L196-S199 WeakPolarHBondContact O-CB 3.31Å; L196-S199 PolarHBondContact O-N 3.21Å; L196-H200 PolarHBondContact O-N 3Å; L196-H200 PolarHBondContact O-ND1 2.99Å; L196-F360 HydrophobicContact CD2-CZ 3.81Å; L196-I364 HydrophobicContact CD2-CD1 4.09Å
197	L	88.3	Confident	88.8	Confident	1 Å²	1	55.8 Å²	55.8	1%	0.005	28%	0.278	C	S	.	.	H	α-helix	trans	-67.3	-40.9	179	-64.6	178.3	0	0	0	111.9	I193 G194 R195 S199 H200 V201 L248 L251 I255 I425	I193-L197 HydrophobicContact CG2-CD1 3.93Å; I193-L197 HydrophobicContact CG2-CG 4.28Å; I193-L197 VanDerWaalsContact O-CG 3.3Å; I193-L197 WeakPolarHBondContact O-CG 3.35Å; I193-L197 PolarHBondContact O-N 3.06Å; G194-L197 PolarHBondContact O-N 3.44Å; R195-L197 VanDerWaalsContact C-N 3.34Å; L197-S199 VanDerWaalsContact C-N 3.25Å; L197-S199 PolarHBondContact O-N 3.41Å; L197-H200 PolarHBondContact O-N 3.48Å; L197-V201 WeakPolarHBondContact O-CG2 3.17Å; L197-V201 PolarHBondContact O-N 2.86Å; L197-L248 HydrophobicContact CB-CD2 4.1Å; L197-L248 HydrophobicContact CD2-CD2 4.09Å; L197-L251 HydrophobicContact CD1-CD1 4.22Å; L197-L251 HydrophobicContact CD2-CD1 3.47Å; L197-L251 VanDerWaalsContact CD2-CD1 3.47Å; L197-L251 HydrophobicContact CG-CD1 4.46Å; L197-I255 HydrophobicContact CD1-CD1 3.48Å; L197-I255 VanDerWaalsContact CD1-CD1 3.48Å; L197-I255 HydrophobicContact CD1-CG1 4.4Å; L197-I425 HydrophobicContact CB-CD1 4.45Å
198	K	87.9	Confident	89.2	Confident	102 Å²	102	54.1 Å²	54.1	44%	0.443	27%	0.271	S	S	.	.	H	α-helix	trans	-57.6	-39.2	171.1	-73.4	175.9	-175.1	-178.5	0	112	G194 R195 K202 I425	G194-K198 VanDerWaalsContact O-CG 3.31Å; G194-K198 WeakPolarHBondContact O-CG 2.73Å; G194-K198 PolarHBondContact O-N 2.95Å; R195-K198 PolarHBondContact O-N 3.47Å; K198-K202 PolarHBondContact O-N 2.92Å; K198-I425 HydrophobicContact CD-CG2 4.47Å; K198-I425 HydrophobicContact CG-CG2 3.97Å
199	S	90.1	Very high	89.6	Confident	73 Å²	73	56.9 Å²	56.9	51%	0.51	28%	0.277	S	S	.	.	H	α-helix	trans	-68.2	-35.9	174.5	-166.8	0	0	0	0	112.5	R195 L196 L197 K202 L203	R195-S199 PolarHBondContact O-N 2.89Å; L196-S199 WeakPolarHBondContact O-CB 3.31Å; L196-S199 PolarHBondContact O-N 3.21Å; L197-S199 VanDerWaalsContact C-N 3.25Å; L197-S199 PolarHBondContact O-N 3.41Å; S199-K202 PolarHBondContact O-N 3.04Å; S199-L203 WeakPolarHBondContact O-CB 3.03Å; S199-L203 PolarHBondContact O-N 3.2Å
200	H	88.9	Confident	90.1	Very high	23 Å²	23	58.7 Å²	58.7	11%	0.106	28%	0.283	C	S	.	.	H	α-helix	trans	-67.7	-37.4	176.1	-81.6	73.1	0	0	0	112.2	L196 L197 L203 A204 Y367	L196-H200 PolarHBondContact O-N 3Å; L196-H200 PolarHBondContact O-ND1 2.99Å; L197-H200 PolarHBondContact O-N 3.48Å; H200-L203 PolarHBondContact O-N 2.82Å; H200-A204 PolarHBondContact O-N 3.33Å; H200-Y367 AromaticContact CD2-CE1 3.99Å
201	V	88.1	Confident	90.6	Very high	10 Å²	10	58.5 Å²	58.5	6%	0.061	28%	0.282	C	S	.	.	H	α-helix	trans	-59.1	-49.7	173.4	174.9	0	0	0	0	110.4	L197 L203 A204 E205 L248 V422	L197-V201 WeakPolarHBondContact O-CG2 3.17Å; L197-V201 PolarHBondContact O-N 2.86Å; V201-L203 VanDerWaalsContact C-N 3.28Å; V201-L203 PolarHBondContact O-N 3.37Å; V201-A204 WeakPolarHBondContact O-CB 3.44Å; V201-A204 PolarHBondContact O-N 3.17Å; V201-A204 VanDerWaalsContact O-N 3.1Å; V201-E205 PolarHBondContact O-N 2.97Å; V201-L248 HydrophobicContact CG2-CD1 3.47Å; V201-L248 VanDerWaalsContact CG2-CD1 3.47Å; V201-L248 HydrophobicContact CG2-CD2 4.03Å; V201-L248 HydrophobicContact CG2-CG 4.4Å; V201-V422 HydrophobicContact CG1-CG2 4.05Å; V201-V422 HydrophobicContact CG2-CG2 4.34Å
202	K	91	Very high	90.9	Very high	140 Å²	140	59 Å²	59	61%	0.609	28%	0.284	S	S	*	.	H	α-helix	trans	-61.2	-37.8	177.1	-68.9	-177.6	178.4	-170.6	0	112.6	K198 S199 A204 E205 V206	K198-K202 PolarHBondContact O-N 2.92Å; S199-K202 PolarHBondContact O-N 3.04Å; K202-A204 VanDerWaalsContact C-N 3.32Å; K202-E205 PolarHBondContact O-N 3.32Å; K202-V206 WeakPolarHBondContact O-CG2 3.49Å; K202-V206 PolarHBondContact O-N 2.82Å; K202-V206 VanDerWaalsContact O-N 3.1Å
203	L	91.6	Very high	91.3	Very high	65 Å²	65	57.9 Å²	57.9	34%	0.34	28%	0.282	S	S	.	.	H	α-helix	trans	-66.4	-37	176.3	-177.2	62.4	0	0	0	111.4	S199 H200 V201 V206 Y207	S199-L203 WeakPolarHBondContact O-CB 3.03Å; S199-L203 PolarHBondContact O-N 3.2Å; H200-L203 PolarHBondContact O-N 2.82Å; V201-L203 VanDerWaalsContact C-N 3.28Å; V201-L203 PolarHBondContact O-N 3.37Å; L203-V206 PolarHBondContact O-N 3.47Å; L203-Y207 HydrophobicContact CD1-CE1 4.03Å; L203-Y207 HydrophobicContact CD1-CE2 4.16Å; L203-Y207 HydrophobicContact CD2-CE2 3.93Å; L203-Y207 HydrophobicContact CG-CD2 4.2Å; L203-Y207 HydrophobicContact CG-CE1 4.36Å; L203-Y207 HydrophobicContact CG-CE2 3.58Å; L203-Y207 WeakPolarHBondContact O-CD2 3.38Å; L203-Y207 PolarHBondContact O-N 2.82Å
204	A	91.7	Very high	91.6	Very high	4 Å²	4	59.5 Å²	59.5	3%	0.033	29%	0.289	C	S	.	.	H	α-helix	trans	-63.7	-44.1	174.2	0	0	0	0	0	111.5	H200 V201 K202 V206 Y207 K208 E241 A244	H200-A204 PolarHBondContact O-N 3.33Å; V201-A204 WeakPolarHBondContact O-CB 3.44Å; V201-A204 PolarHBondContact O-N 3.17Å; V201-A204 VanDerWaalsContact O-N 3.1Å; K202-A204 VanDerWaalsContact C-N 3.32Å; A204-V206 VanDerWaalsContact C-N 3.29Å; A204-V206 PolarHBondContact O-N 2.89Å; A204-Y207 WeakPolarHBondContact O-CB 3.37Å; A204-Y207 PolarHBondContact O-N 3.46Å; A204-K208 PolarHBondContact O-N 3.23Å; A204-E241 HydrophobicContact CB-CG 4.29Å; A204-E241 VanDerWaalsContact O-CG 3.26Å; A204-E241 WeakPolarHBondContact O-CG 3.35Å; A204-A244 HydrophobicContact CB-CB 3.67Å
205	E	91.4	Very high	91.8	Very high	91 Å²	91	61.5 Å²	61.5	43%	0.425	30%	0.295	S	S	.	.	H	α-helix	trans	-56	-45.3	173.7	-68.7	166.9	-179.7	0	0	111.2	V201 K202 Y207 K208 D209	V201-E205 PolarHBondContact O-N 2.97Å; K202-E205 PolarHBondContact O-N 3.32Å; E205-Y207 VanDerWaalsContact C-N 3.34Å; E205-Y207 PolarHBondContact O-N 3.42Å; E205-K208 VanDerWaalsContact O-CB 3.26Å; E205-K208 WeakPolarHBondContact O-CB 3.31Å; E205-K208 PolarHBondContact O-N 2.71Å; E205-K208 VanDerWaalsContact O-N 3.15Å; E205-D209 PolarHBondContact O-N 3.27Å
206	V	94.2	Very high	91.9	Very high	65 Å²	65	58.5 Å²	58.5	39%	0.394	29%	0.289	S	S	.	.	H	α-helix	trans	-62.8	-40.1	175.4	171.9	0	0	0	0	111.8	K202 L203 A204 K208 D209 F210	K202-V206 WeakPolarHBondContact O-CG2 3.49Å; K202-V206 PolarHBondContact O-N 2.82Å; K202-V206 VanDerWaalsContact O-N 3.1Å; L203-V206 PolarHBondContact O-N 3.47Å; A204-V206 VanDerWaalsContact C-N 3.29Å; A204-V206 PolarHBondContact O-N 2.89Å; V206-K208 VanDerWaalsContact C-N 3.31Å; V206-K208 PolarHBondContact O-N 3.06Å; V206-D209 PolarHBondContact O-N 3.4Å; V206-F210 HydrophobicContact CG1-CD2 3.61Å; V206-F210 HydrophobicContact CG1-CE2 3.62Å; V206-F210 VanDerWaalsContact O-CD2 3.3Å; V206-F210 WeakPolarHBondContact O-CD2 2.95Å; V206-F210 PolarHBondContact O-N 3.01Å
207	Y	93.9	Very high	91.9	Very high	43 Å²	43	59.1 Å²	59.1	17%	0.169	29%	0.291	C	S	.	.	H	α-helix	trans	-63.8	-36.2	174.5	-67.4	-34.2	0	0	0	112.5	L203 A204 E205 G211 H237 M240	L203-Y207 HydrophobicContact CD1-CE1 4.03Å; L203-Y207 HydrophobicContact CD1-CE2 4.16Å; L203-Y207 HydrophobicContact CD2-CE2 3.93Å; L203-Y207 HydrophobicContact CG-CD2 4.2Å; L203-Y207 HydrophobicContact CG-CE1 4.36Å; L203-Y207 HydrophobicContact CG-CE2 3.58Å; L203-Y207 WeakPolarHBondContact O-CD2 3.38Å; L203-Y207 PolarHBondContact O-N 2.82Å; A204-Y207 WeakPolarHBondContact O-CB 3.37Å; A204-Y207 PolarHBondContact O-N 3.46Å; E205-Y207 VanDerWaalsContact C-N 3.34Å; E205-Y207 PolarHBondContact O-N 3.42Å; Y207-G211 PolarHBondContact O-N 2.91Å; Y207-H237 AromaticContact CD1-CD2 3.89Å; Y207-H237 WeakPolarHBondContact O-CB 3.43Å; Y207-M240 HydrophobicContact CD2-CB 3.8Å; Y207-M240 HydrophobicContact CD2-CE 4.46Å; Y207-M240 HydrophobicContact CE1-CE 3.91Å; Y207-M240 HydrophobicContact CE1-SD 4.44Å; Y207-M240 HydrophobicContact CE2-CB 4.07Å; Y207-M240 HydrophobicContact CE2-CE 3.69Å; Y207-M240 HydrophobicContact CG-CB 4.23Å; Y207-M240 VanDerWaalsContact OH-CE 3.29Å; Y207-M240 WeakPolarHBondContact OH-CE 3.45Å
208	K	93.1	Very high	91.9	Very high	43 Å²	43	59.3 Å²	59.3	19%	0.187	29%	0.294	C	S	.	.	H	α-helix	trans	-57.4	-54.1	171.9	-166	-176.2	175.9	177.1	0	110.4	A204 E205 V206 F210 G211 D212 E241 E411 E415	A204-K208 PolarHBondContact O-N 3.23Å; E205-K208 VanDerWaalsContact O-CB 3.26Å; E205-K208 WeakPolarHBondContact O-CB 3.31Å; E205-K208 PolarHBondContact O-N 2.71Å; E205-K208 VanDerWaalsContact O-N 3.15Å; V206-K208 VanDerWaalsContact C-N 3.31Å; V206-K208 PolarHBondContact O-N 3.06Å; K208-F210 PolarHBondContact O-N 3.42Å; K208-G211 WeakPolarHBondContact O-CA 3.2Å; K208-G211 PolarHBondContact O-N 3.48Å; K208-D212 PolarHBondContact O-N 3.25Å; K208-E241 HydrophobicContact CB-CG 3.99Å; K208-E411 WeakPolarHBondContact CE-OE1 3.38Å; K208-E411 IonicContact NZ-OE1 2.61Å; K208-E411 PolarHBondContact NZ-OE1 3.09Å; K208-E415 IonicContact NZ-OE1 3.89Å; K208-E415 PolarHBondContact NZ-OE1 3.39Å
209	D	95.5	Very high	92	Very high	94 Å²	94	58 Å²	58	50%	0.503	30%	0.298	S	S	.	.	H	α-helix	trans	-59.2	-45.1	-177.5	-64	-15.9	0	0	0	112	E205 V206 G211 D212 I213	E205-D209 PolarHBondContact O-N 3.27Å; V206-D209 PolarHBondContact O-N 3.4Å; D209-G211 VanDerWaalsContact C-N 3.33Å; D209-G211 PolarHBondContact O-N 3.29Å; D209-D212 PolarHBondContact O-N 3.24Å; D209-I213 WeakPolarHBondContact O-CD1 3.49Å; D209-I213 VanDerWaalsContact O-CG1 3.25Å; D209-I213 WeakPolarHBondContact O-CG1 3.46Å; D209-I213 PolarHBondContact O-N 3.48Å
210	F	94.5	Very high	91.9	Very high	96 Å²	96	60.1 Å²	60.1	42%	0.421	30%	0.299	S	S	.	.	H	α-helix	trans	-61.8	-42.6	174.6	-89.9	-74	0	0	0	111.8	V206 K208 D212 I213 F214 H237	V206-F210 HydrophobicContact CG1-CD2 3.61Å; V206-F210 HydrophobicContact CG1-CE2 3.62Å; V206-F210 VanDerWaalsContact O-CD2 3.3Å; V206-F210 WeakPolarHBondContact O-CD2 2.95Å; V206-F210 PolarHBondContact O-N 3.01Å; K208-F210 PolarHBondContact O-N 3.42Å; F210-D212 VanDerWaalsContact C-N 3.33Å; F210-D212 PolarHBondContact O-N 2.96Å; F210-I213 PolarHBondContact O-N 2.81Å; F210-F214 HydrophobicContact CB-CD2 4.31Å; F210-F214 HydrophobicContact CB-CE2 4.13Å; F210-F214 AromaticContact CD1-CE2 3.77Å; F210-F214 HydrophobicContact CD1-CE2 3.77Å; F210-F214 HydrophobicContact CD1-CZ 4.15Å; F210-F214 HydrophobicContact CG-CE2 4.38Å; F210-F214 WeakPolarHBondContact O-CB 3.47Å; F210-F214 WeakPolarHBondContact O-CD2 3.38Å; F210-F214 WeakPolarHBondContact O-CG 3.33Å; F210-F214 PolarHBondContact O-N 3.36Å; F210-H237 HydrophobicContact CB-CB 4.34Å; F210-H237 VanDerWaalsContact CB-CD2 3.46Å; F210-H237 WeakPolarHBondContact CB-CD2 3.36Å
211	G	94.2	Very high	91.6	Very high	0 Å²	0	59.9 Å²	59.9	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-53.9	-51.9	176.4	0	0	0	0	0	111.6	Y207 K208 D209 F214 F215	Y207-G211 PolarHBondContact O-N 2.91Å; K208-G211 WeakPolarHBondContact O-CA 3.2Å; K208-G211 PolarHBondContact O-N 3.48Å; D209-G211 VanDerWaalsContact C-N 3.33Å; D209-G211 PolarHBondContact O-N 3.29Å; G211-F214 PolarHBondContact O-N 3.39Å; G211-F215 VanDerWaalsContact O-CD2 3.22Å; G211-F215 WeakPolarHBondContact O-CD2 3.34Å; G211-F215 PolarHBondContact O-N 3.09Å
212	D	93.8	Very high	91.4	Very high	55 Å²	55	63.6 Å²	63.6	29%	0.294	32%	0.322	S	S	.	.	H	α-helix	trans	-64.6	-44.1	-177.3	-62.8	-20.5	0	0	0	112	K208 D209 F210 F214 F215 E216 R238	K208-D212 PolarHBondContact O-N 3.25Å; D209-D212 PolarHBondContact O-N 3.24Å; F210-D212 VanDerWaalsContact C-N 3.33Å; F210-D212 PolarHBondContact O-N 2.96Å; D212-F214 VanDerWaalsContact C-N 3.35Å; D212-F214 PolarHBondContact O-N 3.48Å; D212-F215 PolarHBondContact O-N 3.24Å; D212-E216 WeakPolarHBondContact O-CB 3.39Å; D212-E216 PolarHBondContact O-N 2.92Å; D212-R238 IonicContact OD1-CZ 3.26Å; D212-R238 IonicContact OD1-NE 2.73Å; D212-R238 PolarHBondContact OD1-NE 2.87Å; D212-R238 VanDerWaalsContact OD1-NE 3.1Å; D212-R238 IonicContact OD1-NH2 2.75Å; D212-R238 PolarHBondContact OD1-NH2 2.73Å
213	I	95.1	Very high	91.1	Very high	85 Å²	85	60 Å²	60	44%	0.436	31%	0.308	S	S	.	.	H	α-helix	trans	-61.2	-42.9	176	-68	166	0	0	0	111.2	D209 F210 E216 I217	D209-I213 WeakPolarHBondContact O-CD1 3.49Å; D209-I213 VanDerWaalsContact O-CG1 3.25Å; D209-I213 WeakPolarHBondContact O-CG1 3.46Å; D209-I213 PolarHBondContact O-N 3.48Å; F210-I213 PolarHBondContact O-N 2.81Å; I213-E216 PolarHBondContact O-N 3.21Å; I213-I217 HydrophobicContact CG2-CD1 3.81Å; I213-I217 HydrophobicContact CG2-CG1 4.43Å; I213-I217 VanDerWaalsContact O-CG1 3.3Å; I213-I217 WeakPolarHBondContact O-CG1 3.44Å; I213-I217 PolarHBondContact O-N 3.46Å
214	F	93.7	Very high	90.8	Very high	38 Å²	38	62.1 Å²	62.1	17%	0.167	32%	0.323	C	S	.	.	H	α-helix	trans	-67.3	-38.5	179.5	-77.4	-50.2	0	0	0	112.5	F210 G211 D212 G218 F230 F233 H237	F210-F214 HydrophobicContact CB-CD2 4.31Å; F210-F214 HydrophobicContact CB-CE2 4.13Å; F210-F214 AromaticContact CD1-CE2 3.77Å; F210-F214 HydrophobicContact CD1-CE2 3.77Å; F210-F214 HydrophobicContact CD1-CZ 4.15Å; F210-F214 HydrophobicContact CG-CE2 4.38Å; F210-F214 WeakPolarHBondContact O-CB 3.47Å; F210-F214 WeakPolarHBondContact O-CD2 3.38Å; F210-F214 WeakPolarHBondContact O-CG 3.33Å; F210-F214 PolarHBondContact O-N 3.36Å; G211-F214 PolarHBondContact O-N 3.39Å; D212-F214 VanDerWaalsContact C-N 3.35Å; D212-F214 PolarHBondContact O-N 3.48Å; F214-G218 PolarHBondContact O-N 2.88Å; F214-F230 WeakPolarHBondContact CB-O 3.4Å; F214-F230 AromaticContact CD1-CD1 3.84Å; F214-F230 HydrophobicContact CD1-CD1 3.84Å; F214-F230 HydrophobicContact CD1-CE1 4.48Å; F214-F230 HydrophobicContact CE1-CD1 4.28Å; F214-F233 HydrophobicContact CB-CB 4.38Å; F214-F233 HydrophobicContact CD1-CB 4.14Å; F214-F233 HydrophobicContact CD2-CB 3.81Å; F214-F233 HydrophobicContact CE1-CB 4.36Å; F214-F233 HydrophobicContact CE2-CB 4.09Å; F214-F233 HydrophobicContact CG-CB 3.86Å; F214-F233 HydrophobicContact CZ-CB 4.34Å; F214-H237 AromaticContact CD2-ND1 3.81Å; F214-H237 AromaticContact CE2-CE1 3.45Å; F214-H237 VanDerWaalsContact CE2-CE1 3.45Å; F214-H237 WeakPolarHBondContact CE2-CE1 3.35Å; F214-H237 AromaticContact CE2-ND1 3.71Å; F214-H237 AromaticContact CE2-NE2 3.97Å
215	F	92.1	Very high	90.5	Very high	47 Å²	47	67.5 Å²	67.5	21%	0.206	35%	0.351	C	S	.	.	H	α-helix	trans	-64.1	-41.5	172.6	-86.8	-70.6	0	0	0	112	G211 D212 G218 S219 M231 E235 R238	G211-F215 VanDerWaalsContact O-CD2 3.22Å; G211-F215 WeakPolarHBondContact O-CD2 3.34Å; G211-F215 PolarHBondContact O-N 3.09Å; D212-F215 PolarHBondContact O-N 3.24Å; F215-G218 PolarHBondContact O-N 2.94Å; F215-S219 WeakPolarHBondContact O-CB 3.37Å; F215-S219 PolarHBondContact O-N 3.49Å; F215-M231 HydrophobicContact CD1-CE 3.47Å; F215-M231 VanDerWaalsContact CD1-CE 3.47Å; F215-M231 HydrophobicContact CD1-SD 3.48Å; F215-M231 WeakPolarHBondContact CD1-SD 3.38Å; F215-M231 HydrophobicContact CE1-CE 3.56Å; F215-M231 HydrophobicContact CE1-SD 3.98Å; F215-M231 HydrophobicContact CG-SD 4.47Å; F215-E235 HydrophobicContact CZ-CB 4.06Å; F215-R238 HydrophobicContact CE2-CG 4.22Å
216	E	91.6	Very high	90.3	Very high	99 Å²	99	63.2 Å²	63.2	46%	0.463	33%	0.331	S	S	.	.	H	α-helix	trans	-59.6	-52.1	176.1	-173.7	-178.1	175.8	0	0	111	D212 I213 G218 S219 H220	D212-E216 WeakPolarHBondContact O-CB 3.39Å; D212-E216 PolarHBondContact O-N 2.92Å; I213-E216 PolarHBondContact O-N 3.21Å; E216-G218 PolarHBondContact O-N 3.05Å; E216-S219 PolarHBondContact O-N 3.16Å; E216-S219 PolarHBondContact O-OG 3.48Å; E216-H220 PolarHBondContact O-CD2 3.2Å; E216-H220 PolarHBondContact O-N 2.91Å
217	I	89.5	Confident	90	Very high	67 Å²	67	60.9 Å²	60.9	34%	0.344	32%	0.319	S	S	.	.	H	α-helix	trans	-59.6	-48.1	177.5	-64.3	167.4	0	0	0	110.6	I213 S219 H220 E221 F230	I213-I217 HydrophobicContact CG2-CD1 3.81Å; I213-I217 HydrophobicContact CG2-CG1 4.43Å; I213-I217 VanDerWaalsContact O-CG1 3.3Å; I213-I217 WeakPolarHBondContact O-CG1 3.44Å; I213-I217 PolarHBondContact O-N 3.46Å; I217-S219 PolarHBondContact O-N 2.99Å; I217-H220 PolarHBondContact O-N 3.25Å; I217-H220 VanDerWaalsContact O-N 3.11Å; I217-E221 WeakPolarHBondContact O-CB 3.45Å; I217-E221 PolarHBondContact O-N 3.5Å; I217-F230 HydrophobicContact CB-CG 4.38Å; I217-F230 HydrophobicContact CG2-CD1 4.03Å; I217-F230 HydrophobicContact CG2-CD2 3.57Å; I217-F230 HydrophobicContact CG2-CE1 4.05Å; I217-F230 HydrophobicContact CG2-CE2 3.6Å; I217-F230 HydrophobicContact CG2-CG 3.8Å; I217-F230 HydrophobicContact CG2-CZ 3.84Å
218	G	88.1	Confident	89.7	Confident	6 Å²	6	64.6 Å²	64.6	6%	0.062	34%	0.338	C	S	.	.	H	α-helix	trans	-60.3	-33.4	-179.5	0	0	0	0	0	113.4	F214 F215 E216 H220 A227	F214-G218 PolarHBondContact O-N 2.88Å; F215-G218 PolarHBondContact O-N 2.94Å; E216-G218 PolarHBondContact O-N 3.05Å; G218-H220 VanDerWaalsContact C-N 3.32Å; G218-H220 PolarHBondContact O-N 3.46Å; G218-A227 WeakPolarHBondContact O-CB 3.42Å
219	S	89.2	Confident	89.6	Confident	75 Å²	75	62.6 Å²	62.6	52%	0.524	33%	0.329	S	S	.	.	H	α-helix	trans	-72.9	-23	178.1	77.5	0	0	0	0	114.1	F215 E216 I217	F215-S219 WeakPolarHBondContact O-CB 3.37Å; F215-S219 PolarHBondContact O-N 3.49Å; E216-S219 PolarHBondContact O-N 3.16Å; E216-S219 PolarHBondContact O-OG 3.48Å; I217-S219 PolarHBondContact O-N 2.99Å
220	H	87.7	Confident	89.4	Confident	117 Å²	117	59.4 Å²	59.4	54%	0.542	31%	0.311	S	S	.	.	H	α-helix	trans	-104.3	-8	-178.7	-67.9	-54	0	0	0	113.6	E216 I217 G218 P222	E216-H220 PolarHBondContact O-CD2 3.2Å; E216-H220 PolarHBondContact O-N 2.91Å; I217-H220 PolarHBondContact O-N 3.25Å; I217-H220 VanDerWaalsContact O-N 3.11Å; G218-H220 VanDerWaalsContact C-N 3.32Å; G218-H220 PolarHBondContact O-N 3.46Å; H220-P222 WeakPolarHBondContact O-CD 3.42Å
221	E	83.9	Confident	89.2	Confident	18 Å²	18	58.4 Å²	58.4	8%	0.084	31%	0.308	C	S	.	.			trans	-77.9	120.6	-177.2	-179.4	55.6	-129.5	0	0	111.7	I217 Q223 A227 F230	I217-E221 WeakPolarHBondContact O-CB 3.45Å; I217-E221 PolarHBondContact O-N 3.5Å; E221-Q223 PolarHBondContact O-N 3.13Å; E221-Q223 PolarHBondContact OE1-N 3.05Å; E221-A227 HydrophobicContact CB-CB 4.02Å; E221-A227 HydrophobicContact CG-CB 4.24Å; E221-F230 HydrophobicContact CB-CD2 4.48Å; E221-F230 HydrophobicContact CG-CD2 4.39Å; E221-F230 HydrophobicContact CG-CE2 4.42Å
222	P	84	Confident	89.1	Confident	87 Å²	87	59.4 Å²	59.4	57%	0.565	32%	0.315	S	S	*	.	S	Bend	trans	-70.9	-28.2	-179.3	26.4	-35.7	0	0	0	113.7	H220 V224	H220-P222 WeakPolarHBondContact O-CD 3.42Å; P222-V224 PolarHBondContact O-N 3.41Å
223	Q	84.7	Confident	89.1	Confident	66 Å²	66	58.2 Å²	58.2	31%	0.308	31%	0.307	S	S	.	.	S	Bend	trans	-81.6	114.1	-179.3	-178.9	168.3	-13.6	0	0	110.9	E221 N225 S226 A227 D385	E221-Q223 PolarHBondContact O-N 3.13Å; E221-Q223 PolarHBondContact OE1-N 3.05Å; Q223-N225 VanDerWaalsContact C-N 3.34Å; Q223-N225 PolarHBondContact O-N 3.29Å; Q223-S226 PolarHBondContact O-N 2.86Å; Q223-A227 WeakPolarHBondContact O-CB 3.42Å; Q223-A227 PolarHBondContact O-N 3.45Å; Q223-D385 PolarHBondContact OE1-O 3.09Å
224	V	85.3	Confident	89.1	Confident	109 Å²	109	54.2 Å²	54.2	66%	0.661	29%	0.286	S	S	*	.	H	α-helix	trans	-51.1	-46.8	-176.2	179	0	0	0	0	113.3	P222 S226 A227 E228	P222-V224 PolarHBondContact O-N 3.41Å; V224-S226 VanDerWaalsContact C-N 3.32Å; V224-S226 PolarHBondContact O-N 3.11Å; V224-A227 PolarHBondContact O-N 2.86Å; V224-E228 WeakPolarHBondContact O-CB 3.25Å; V224-E228 PolarHBondContact O-N 3.27Å
225	N	85.9	Confident	89.1	Confident	116 Å²	116	57.7 Å²	57.7	62%	0.62	30%	0.303	S	S	*	.	H	α-helix	trans	-64.8	-37.4	-179.1	-65.9	0.6	0	0	0	112.3	Q223 A229	Q223-N225 VanDerWaalsContact C-N 3.34Å; Q223-N225 PolarHBondContact O-N 3.29Å; N225-A229 WeakPolarHBondContact O-CB 3.28Å; N225-A229 PolarHBondContact O-N 3.33Å
226	S	86.6	Confident	89.2	Confident	1 Å²	1	55.8 Å²	55.8	1%	0.007	30%	0.295	C	S	.	.	H	α-helix	trans	-76.3	-40.6	-178.9	-54.1	0	0	0	0	110.5	Q223 V224 A229 F230 D385	Q223-S226 PolarHBondContact O-N 2.86Å; V224-S226 VanDerWaalsContact C-N 3.32Å; V224-S226 PolarHBondContact O-N 3.11Å; S226-A229 PolarHBondContact O-N 3.05Å; S226-F230 WeakPolarHBondContact O-CD2 3.42Å; S226-F230 PolarHBondContact O-N 2.86Å; S226-D385 PolarHBondContact OG-O 3.34Å
227	A	87.1	Confident	89.4	Confident	16 Å²	16	52.7 Å²	52.7	13%	0.132	28%	0.281	C	S	.	.	H	α-helix	trans	-55.9	-51.1	169.8	0	0	0	0	0	111.2	G218 E221 Q223 V224 A229 F230 M231	G218-A227 WeakPolarHBondContact O-CB 3.42Å; E221-A227 HydrophobicContact CB-CB 4.02Å; E221-A227 HydrophobicContact CG-CB 4.24Å; Q223-A227 WeakPolarHBondContact O-CB 3.42Å; Q223-A227 PolarHBondContact O-N 3.45Å; V224-A227 PolarHBondContact O-N 2.86Å; A227-A229 VanDerWaalsContact C-N 3.31Å; A227-A229 PolarHBondContact O-N 2.95Å; A227-F230 PolarHBondContact O-N 3.37Å; A227-M231 WeakPolarHBondContact O-CG 3.46Å; A227-M231 PolarHBondContact O-N 3.19Å
228	E	88.4	Confident	89.6	Confident	121 Å²	121	54.2 Å²	54.2	57%	0.565	28%	0.282	S	S	*	.	H	α-helix	trans	-59.7	-40.4	177.5	-174.2	177.8	-174.7	0	0	112.2	V224 M231 T232	V224-E228 WeakPolarHBondContact O-CB 3.25Å; V224-E228 PolarHBondContact O-N 3.27Å; E228-M231 PolarHBondContact O-N 3.43Å; E228-T232 WeakPolarHBondContact O-CB 3.44Å; E228-T232 PolarHBondContact O-N 3.48Å; E228-T232 PolarHBondContact O-OG1 2.96Å
229	A	89.9	Confident	89.9	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.008	29%	0.292	C	S	.	.	H	α-helix	trans	-61.4	-48.4	175.4	0	0	0	0	0	111.8	N225 S226 A227 T232 F233 L381 I384	N225-A229 WeakPolarHBondContact O-CB 3.28Å; N225-A229 PolarHBondContact O-N 3.33Å; S226-A229 PolarHBondContact O-N 3.05Å; A227-A229 VanDerWaalsContact C-N 3.31Å; A227-A229 PolarHBondContact O-N 2.95Å; A229-T232 PolarHBondContact O-N 2.93Å; A229-F233 HydrophobicContact CB-CE2 4.38Å; A229-F233 WeakPolarHBondContact O-CD2 3.45Å; A229-F233 PolarHBondContact O-N 3.39Å; A229-L381 HydrophobicContact CB-CB 4.15Å; A229-L381 HydrophobicContact CB-CD1 4.33Å; A229-L381 HydrophobicContact CB-CD2 4.09Å; A229-L381 HydrophobicContact CB-CG 4.42Å; A229-I384 HydrophobicContact CB-CD1 4.17Å; A229-I384 HydrophobicContact CB-CG1 4.13Å
230	F	91.7	Very high	90.1	Very high	27 Å²	27	53.4 Å²	53.4	12%	0.118	27%	0.27	C	S	.	.	H	α-helix	trans	-62.8	-44.2	177.1	-70.9	-57.7	0	0	0	112.2	F214 I217 E221 S226 A227 T232 F233 G234 I384 V386	F214-F230 WeakPolarHBondContact CB-O 3.4Å; F214-F230 AromaticContact CD1-CD1 3.84Å; F214-F230 HydrophobicContact CD1-CD1 3.84Å; F214-F230 HydrophobicContact CD1-CE1 4.48Å; F214-F230 HydrophobicContact CE1-CD1 4.28Å; I217-F230 HydrophobicContact CB-CG 4.38Å; I217-F230 HydrophobicContact CG2-CD1 4.03Å; I217-F230 HydrophobicContact CG2-CD2 3.57Å; I217-F230 HydrophobicContact CG2-CE1 4.05Å; I217-F230 HydrophobicContact CG2-CE2 3.6Å; I217-F230 HydrophobicContact CG2-CG 3.8Å; I217-F230 HydrophobicContact CG2-CZ 3.84Å; E221-F230 HydrophobicContact CB-CD2 4.48Å; E221-F230 HydrophobicContact CG-CD2 4.39Å; E221-F230 HydrophobicContact CG-CE2 4.42Å; S226-F230 WeakPolarHBondContact O-CD2 3.42Å; S226-F230 PolarHBondContact O-N 2.86Å; A227-F230 PolarHBondContact O-N 3.37Å; F230-T232 VanDerWaalsContact C-N 3.29Å; F230-T232 PolarHBondContact O-N 2.84Å; F230-F233 PolarHBondContact O-N 2.73Å; F230-G234 PolarHBondContact O-N 2.97Å; F230-I384 HydrophobicContact CE2-CG2 4.43Å; F230-I384 HydrophobicContact CZ-CG2 4.42Å; F230-V386 HydrophobicContact CE2-CG2 4.1Å; F230-V386 HydrophobicContact CZ-CG2 3.95Å
231	M	91.6	Very high	90.4	Very high	75 Å²	75	48.3 Å²	48.3	37%	0.369	25%	0.247	S	C	.	.	H	α-helix	trans	-59.4	-41	175.5	-64.4	-65	-77.4	0	0	111.6	F215 A227 E228 G234 E235	F215-M231 HydrophobicContact CD1-CE 3.47Å; F215-M231 VanDerWaalsContact CD1-CE 3.47Å; F215-M231 HydrophobicContact CD1-SD 3.48Å; F215-M231 WeakPolarHBondContact CD1-SD 3.38Å; F215-M231 HydrophobicContact CE1-CE 3.56Å; F215-M231 HydrophobicContact CE1-SD 3.98Å; F215-M231 HydrophobicContact CG-SD 4.47Å; A227-M231 WeakPolarHBondContact O-CG 3.46Å; A227-M231 PolarHBondContact O-N 3.19Å; E228-M231 PolarHBondContact O-N 3.43Å; M231-G234 PolarHBondContact O-N 3.28Å; M231-E235 PolarHBondContact O-N 2.97Å
232	T	91.9	Very high	90.9	Very high	22 Å²	22	53.1 Å²	53.1	14%	0.135	27%	0.268	C	S	.	.	H	α-helix	trans	-65.5	-45.9	176.2	-54	0	0	0	0	111.2	E228 A229 F230 G234 E235 V236 P377 T378 L381	E228-T232 WeakPolarHBondContact O-CB 3.44Å; E228-T232 PolarHBondContact O-N 3.48Å; E228-T232 PolarHBondContact O-OG1 2.96Å; A229-T232 PolarHBondContact O-N 2.93Å; F230-T232 VanDerWaalsContact C-N 3.29Å; F230-T232 PolarHBondContact O-N 2.84Å; T232-G234 VanDerWaalsContact C-N 3.28Å; T232-G234 PolarHBondContact O-N 3.48Å; T232-E235 PolarHBondContact O-N 2.94Å; T232-V236 WeakPolarHBondContact O-CG2 3.17Å; T232-V236 PolarHBondContact O-N 3.08Å; T232-P377 HydrophobicContact CG2-CB 3.93Å; T232-T378 HydrophobicContact CG2-CG2 4.46Å; T232-L381 HydrophobicContact CG2-CD1 3.84Å
233	F	93.3	Very high	91.3	Very high	30 Å²	30	52.9 Å²	52.9	13%	0.132	26%	0.255	C	S	.	.	H	α-helix	trans	-59.3	-41.4	174.4	-73.9	-61.9	0	0	0	111.7	F214 A229 F230 V236 H237 T378 L381 F382 I384	F214-F233 HydrophobicContact CB-CB 4.38Å; F214-F233 HydrophobicContact CD1-CB 4.14Å; F214-F233 HydrophobicContact CD2-CB 3.81Å; F214-F233 HydrophobicContact CE1-CB 4.36Å; F214-F233 HydrophobicContact CE2-CB 4.09Å; F214-F233 HydrophobicContact CG-CB 3.86Å; F214-F233 HydrophobicContact CZ-CB 4.34Å; A229-F233 HydrophobicContact CB-CE2 4.38Å; A229-F233 WeakPolarHBondContact O-CD2 3.45Å; A229-F233 PolarHBondContact O-N 3.39Å; F230-F233 PolarHBondContact O-N 2.73Å; F233-V236 PolarHBondContact O-N 2.92Å; F233-H237 PolarHBondContact O-N 3.38Å; F233-H237 VanDerWaalsContact O-N 3.08Å; F233-H237 PolarHBondContact O-ND1 3.48Å; F233-T378 HydrophobicContact CD1-CG2 4Å; F233-T378 HydrophobicContact CE1-CG2 3.92Å; F233-L381 HydrophobicContact CD2-CD1 4.22Å; F233-L381 HydrophobicContact CE1-CD1 4.23Å; F233-L381 HydrophobicContact CE2-CB 4.35Å; F233-L381 HydrophobicContact CE2-CD1 3.78Å; F233-L381 HydrophobicContact CZ-CB 4.29Å; F233-L381 HydrophobicContact CZ-CD1 3.79Å; F233-F382 AromaticContact CZ-CE2 3.8Å; F233-F382 HydrophobicContact CZ-CE2 3.8Å; F233-F382 AromaticContact CZ-CZ 3.97Å; F233-F382 HydrophobicContact CZ-CZ 3.97Å; F233-I384 HydrophobicContact CE2-CD1 3.66Å; F233-I384 HydrophobicContact CZ-CD1 4.4Å
234	G	93.9	Very high	91.7	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-58	-48.8	175.9	0	0	0	0	0	112	F230 M231 T232 V236 H237 R238	F230-G234 PolarHBondContact O-N 2.97Å; M231-G234 PolarHBondContact O-N 3.28Å; T232-G234 VanDerWaalsContact C-N 3.28Å; T232-G234 PolarHBondContact O-N 3.48Å; G234-V236 PolarHBondContact O-N 2.99Å; G234-H237 PolarHBondContact O-N 2.96Å; G234-R238 PolarHBondContact O-N 3.32Å
235	E	94.4	Very high	91.8	Very high	111 Å²	111	45.8 Å²	45.8	52%	0.519	21%	0.214	S	C	.	.	H	α-helix	trans	-61.5	-44.1	178.6	-174.3	173	-158.3	0	0	112.2	F215 M231 T232 H237 R238 N239	F215-E235 HydrophobicContact CZ-CB 4.06Å; M231-E235 PolarHBondContact O-N 2.97Å; T232-E235 PolarHBondContact O-N 2.94Å; E235-H237 PolarHBondContact O-N 3.24Å; E235-R238 PolarHBondContact O-N 3.49Å; E235-N239 WeakPolarHBondContact O-CB 3.41Å; E235-N239 VanDerWaalsContact O-CG 3.29Å; E235-N239 PolarHBondContact O-N 3.49Å; E235-N239 PolarHBondContact O-ND2 2.91Å
236	V	94.8	Very high	92	Very high	7 Å²	7	46 Å²	46	4%	0.042	21%	0.209	C	C	.	.	H	α-helix	trans	-60.2	-46.3	177.5	174	0	0	0	0	111.5	T232 F233 G234 N239 M240 D374 M375 T378	T232-V236 WeakPolarHBondContact O-CG2 3.17Å; T232-V236 PolarHBondContact O-N 3.08Å; F233-V236 PolarHBondContact O-N 2.92Å; G234-V236 PolarHBondContact O-N 2.99Å; V236-N239 PolarHBondContact O-N 2.73Å; V236-M240 HydrophobicContact CG1-CG 4.42Å; V236-M240 HydrophobicContact CG1-SD 4.08Å; V236-M240 VanDerWaalsContact O-CG 3.28Å; V236-M240 WeakPolarHBondContact O-CG 3.48Å; V236-M240 PolarHBondContact O-N 2.96Å; V236-D374 HydrophobicContact CG1-CB 4.33Å; V236-D374 WeakPolarHBondContact CG2-O 3.46Å; V236-M375 HydrophobicContact CG1-CG 3.9Å; V236-T378 HydrophobicContact CB-CG2 4.47Å; V236-T378 HydrophobicContact CG2-CG2 3.75Å
237	H	95	Very high	92.2	Very high	35 Å²	35	46.2 Å²	46.2	16%	0.162	21%	0.21	C	C	.	.	H	α-helix	trans	-65	-42.3	179.7	-74.4	81.1	0	0	0	111.7	Y207 F210 F214 F233 G234 E235 N239 M240 E241	Y207-H237 AromaticContact CD1-CD2 3.89Å; Y207-H237 WeakPolarHBondContact O-CB 3.43Å; F210-H237 HydrophobicContact CB-CB 4.34Å; F210-H237 VanDerWaalsContact CB-CD2 3.46Å; F210-H237 WeakPolarHBondContact CB-CD2 3.36Å; F214-H237 AromaticContact CD2-ND1 3.81Å; F214-H237 AromaticContact CE2-CE1 3.45Å; F214-H237 VanDerWaalsContact CE2-CE1 3.45Å; F214-H237 WeakPolarHBondContact CE2-CE1 3.35Å; F214-H237 AromaticContact CE2-ND1 3.71Å; F214-H237 AromaticContact CE2-NE2 3.97Å; F233-H237 PolarHBondContact O-N 3.38Å; F233-H237 VanDerWaalsContact O-N 3.08Å; F233-H237 PolarHBondContact O-ND1 3.48Å; G234-H237 PolarHBondContact O-N 2.96Å; E235-H237 PolarHBondContact O-N 3.24Å; H237-N239 VanDerWaalsContact C-N 3.33Å; H237-N239 PolarHBondContact O-N 3.12Å; H237-M240 PolarHBondContact O-N 3.49Å; H237-E241 PolarHBondContact O-N 2.84Å
238	R	94.2	Very high	92.3	Very high	98 Å²	98	46.1 Å²	46.1	37%	0.37	21%	0.208	S	C	.	.	H	α-helix	trans	-62.7	-36.8	173.3	-71.6	-168.4	177.7	172.8	-6.3	112.6	D212 F215 G234 E235 E241 K242	D212-R238 IonicContact OD1-CZ 3.26Å; D212-R238 IonicContact OD1-NE 2.73Å; D212-R238 PolarHBondContact OD1-NE 2.87Å; D212-R238 VanDerWaalsContact OD1-NE 3.1Å; D212-R238 IonicContact OD1-NH2 2.75Å; D212-R238 PolarHBondContact OD1-NH2 2.73Å; F215-R238 HydrophobicContact CE2-CG 4.22Å; G234-R238 PolarHBondContact O-N 3.32Å; E235-R238 PolarHBondContact O-N 3.49Å; R238-E241 WeakPolarHBondContact O-CB 3.44Å; R238-E241 PolarHBondContact O-N 3.44Å; R238-K242 WeakPolarHBondContact O-CG 3.42Å; R238-K242 PolarHBondContact O-N 3.33Å
239	N	94.8	Very high	92.2	Very high	48 Å²	48	44.1 Å²	44.1	26%	0.257	20%	0.198	S	C	.	.	H	α-helix	trans	-69.6	-39.9	176.5	-74.6	-26.4	0	0	0	112.4	E235 V236 H237 E241 K242 R243 D374	E235-N239 WeakPolarHBondContact O-CB 3.41Å; E235-N239 VanDerWaalsContact O-CG 3.29Å; E235-N239 PolarHBondContact O-N 3.49Å; E235-N239 PolarHBondContact O-ND2 2.91Å; V236-N239 PolarHBondContact O-N 2.73Å; H237-N239 VanDerWaalsContact C-N 3.33Å; H237-N239 PolarHBondContact O-N 3.12Å; N239-E241 VanDerWaalsContact C-N 3.28Å; N239-E241 PolarHBondContact O-N 2.88Å; N239-K242 PolarHBondContact O-N 2.94Å; N239-R243 WeakPolarHBondContact O-CG 3.41Å; N239-R243 PolarHBondContact O-N 2.84Å; N239-D374 HydrophobicContact CB-CB 4.47Å
240	M	94	Very high	92.2	Very high	16 Å²	16	47.5 Å²	47.5	8%	0.079	22%	0.216	C	C	.	.	H	α-helix	trans	-60.6	-39.9	174.1	-70.4	176.8	77.2	0	0	111.8	Y207 V236 H237 R243 A244 C371	Y207-M240 HydrophobicContact CD2-CB 3.8Å; Y207-M240 HydrophobicContact CD2-CE 4.46Å; Y207-M240 HydrophobicContact CE1-CE 3.91Å; Y207-M240 HydrophobicContact CE1-SD 4.44Å; Y207-M240 HydrophobicContact CE2-CB 4.07Å; Y207-M240 HydrophobicContact CE2-CE 3.69Å; Y207-M240 HydrophobicContact CG-CB 4.23Å; Y207-M240 VanDerWaalsContact OH-CE 3.29Å; Y207-M240 WeakPolarHBondContact OH-CE 3.45Å; V236-M240 HydrophobicContact CG1-CG 4.42Å; V236-M240 HydrophobicContact CG1-SD 4.08Å; V236-M240 VanDerWaalsContact O-CG 3.28Å; V236-M240 WeakPolarHBondContact O-CG 3.48Å; V236-M240 PolarHBondContact O-N 2.96Å; H237-M240 PolarHBondContact O-N 3.49Å; M240-R243 PolarHBondContact O-N 3.23Å; M240-A244 WeakPolarHBondContact O-CB 3.43Å; M240-A244 PolarHBondContact O-N 3.28Å; M240-C371 HydrophobicContact CE-CB 4.05Å; M240-C371 HydrophobicContact CG-CB 4.19Å
241	E	94	Very high	92.1	Very high	11 Å²	11	46.2 Å²	46.2	5%	0.051	21%	0.211	C	C	.	.	H	α-helix	trans	-59.6	-53.5	173.2	-166.1	-72.7	150.7	0	0	111.6	A204 K208 H237 R238 N239 R243 A244 R245	A204-E241 HydrophobicContact CB-CG 4.29Å; A204-E241 VanDerWaalsContact O-CG 3.26Å; A204-E241 WeakPolarHBondContact O-CG 3.35Å; K208-E241 HydrophobicContact CB-CG 3.99Å; H237-E241 PolarHBondContact O-N 2.84Å; R238-E241 WeakPolarHBondContact O-CB 3.44Å; R238-E241 PolarHBondContact O-N 3.44Å; N239-E241 VanDerWaalsContact C-N 3.28Å; N239-E241 PolarHBondContact O-N 2.88Å; E241-R243 VanDerWaalsContact C-N 3.26Å; E241-R243 PolarHBondContact O-N 3.48Å; E241-A244 WeakPolarHBondContact O-CA 3.25Å; E241-A244 WeakPolarHBondContact O-CB 3.39Å; E241-A244 PolarHBondContact O-N 3.4Å; E241-R245 VanDerWaalsContact CD-CZ 3.49Å; E241-R245 VanDerWaalsContact CD-NE 3.3Å; E241-R245 PolarHBondContact O-N 2.97Å; E241-R245 IonicContact OE1-CZ 3.1Å; E241-R245 IonicContact OE1-NE 2.95Å; E241-R245 PolarHBondContact OE1-NE 3.21Å; E241-R245 IonicContact OE1-NH2 3.36Å; E241-R245 PolarHBondContact OE1-NH2 3.19Å; E241-R245 IonicContact OE2-CZ 3.33Å; E241-R245 VanDerWaalsContact OE2-CZ 3.3Å; E241-R245 IonicContact OE2-NE 3.12Å; E241-R245 PolarHBondContact OE2-NE 3.46Å; E241-R245 IonicContact OE2-NH1 2.7Å; E241-R245 IonicContact OE2-NH2 3.19Å; E241-R245 PolarHBondContact OE2-NH2 2.99Å
242	K	93.2	Very high	91.8	Very high	119 Å²	119	46.9 Å²	46.9	52%	0.517	21%	0.209	S	C	.	.	H	α-helix	trans	-57.3	-38.9	176.8	-70.9	176.2	-177.4	-175.1	0	111.8	R238 N239 R245 K246	R238-K242 WeakPolarHBondContact O-CG 3.42Å; R238-K242 PolarHBondContact O-N 3.33Å; N239-K242 PolarHBondContact O-N 2.94Å; K242-R245 PolarHBondContact O-N 2.67Å; K242-K246 PolarHBondContact O-N 3.47Å; K242-K246 VanDerWaalsContact O-N 3.09Å
243	R	93.6	Very high	91.6	Very high	81 Å²	81	48.5 Å²	48.5	31%	0.306	22%	0.22	S	C	.	.	H	α-helix	trans	-67.6	-38.5	175.3	-72.9	-174.6	-171	-94.5	7.8	112.5	N239 M240 E241 K246 L247 Y367 G370 D374	N239-R243 WeakPolarHBondContact O-CG 3.41Å; N239-R243 PolarHBondContact O-N 2.84Å; M240-R243 PolarHBondContact O-N 3.23Å; E241-R243 VanDerWaalsContact C-N 3.26Å; E241-R243 PolarHBondContact O-N 3.48Å; R243-K246 PolarHBondContact O-N 3.34Å; R243-L247 PolarHBondContact O-N 2.93Å; R243-Y367 HydrophobicContact CB-CD2 3.93Å; R243-Y367 HydrophobicContact CB-CE2 4.09Å; R243-G370 PolarHBondContact NE-O 3.18Å; R243-D374 WeakPolarHBondContact CD-OD2 3.5Å; R243-D374 IonicContact CZ-OD1 2.77Å; R243-D374 IonicContact CZ-OD2 3.12Å; R243-D374 VanDerWaalsContact NE-CG 3.26Å; R243-D374 IonicContact NE-OD1 2.84Å; R243-D374 PolarHBondContact NE-OD1 2.78Å; R243-D374 IonicContact NE-OD2 3.8Å; R243-D374 PolarHBondContact NE-OD2 3.06Å; R243-D374 IonicContact NH2-OD1 3.16Å; R243-D374 PolarHBondContact NH2-OD1 3.4Å; R243-D374 IonicContact NH2-OD2 2.75Å
244	A	91.6	Very high	91.3	Very high	1 Å²	1	47.1 Å²	47.1	1%	0.008	21%	0.214	C	C	.	.	H	α-helix	trans	-64.7	-39.8	175.6	0	0	0	0	0	111.3	A204 M240 E241 L247 L248 Y367	A204-A244 HydrophobicContact CB-CB 3.67Å; M240-A244 WeakPolarHBondContact O-CB 3.43Å; M240-A244 PolarHBondContact O-N 3.28Å; E241-A244 WeakPolarHBondContact O-CA 3.25Å; E241-A244 WeakPolarHBondContact O-CB 3.39Å; E241-A244 PolarHBondContact O-N 3.4Å; A244-L247 WeakPolarHBondContact O-CB 3.49Å; A244-L247 PolarHBondContact O-N 3.1Å; A244-L248 WeakPolarHBondContact O-CG 3.31Å; A244-L248 PolarHBondContact O-N 3.38Å; A244-Y367 HydrophobicContact CB-CE2 3.75Å
245	R	87.9	Confident	90.8	Very high	26 Å²	26	47.8 Å²	47.8	10%	0.098	22%	0.217	C	C	.	.	H	α-helix	trans	-58.6	-49.7	171.7	-67.2	-171.5	-175.5	163.7	13.2	111.7	E241 K242 L247 L248 E249 L414	E241-R245 VanDerWaalsContact CD-CZ 3.49Å; E241-R245 VanDerWaalsContact CD-NE 3.3Å; E241-R245 PolarHBondContact O-N 2.97Å; E241-R245 IonicContact OE1-CZ 3.1Å; E241-R245 IonicContact OE1-NE 2.95Å; E241-R245 PolarHBondContact OE1-NE 3.21Å; E241-R245 IonicContact OE1-NH2 3.36Å; E241-R245 PolarHBondContact OE1-NH2 3.19Å; E241-R245 IonicContact OE2-CZ 3.33Å; E241-R245 VanDerWaalsContact OE2-CZ 3.3Å; E241-R245 IonicContact OE2-NE 3.12Å; E241-R245 PolarHBondContact OE2-NE 3.46Å; E241-R245 IonicContact OE2-NH1 2.7Å; E241-R245 IonicContact OE2-NH2 3.19Å; E241-R245 PolarHBondContact OE2-NH2 2.99Å; K242-R245 PolarHBondContact O-N 2.67Å; R245-L247 VanDerWaalsContact C-N 3.27Å; R245-L247 PolarHBondContact O-N 3.18Å; R245-L248 WeakPolarHBondContact O-CB 3.5Å; R245-L248 PolarHBondContact O-N 2.89Å; R245-E249 PolarHBondContact O-N 3.47Å; R245-E249 VanDerWaalsContact O-N 3.08Å; R245-L414 VanDerWaalsContact NH1-CB 3.26Å
246	K	90.1	Very high	90.4	Very high	119 Å²	119	45.4 Å²	45.4	52%	0.517	21%	0.213	S	C	.	.	H	α-helix	trans	-61.3	-33.4	178.1	-168.4	169.7	-170.1	163.5	0	113.1	K242 R243 N250	K242-K246 PolarHBondContact O-N 3.47Å; K242-K246 VanDerWaalsContact O-N 3.09Å; R243-K246 PolarHBondContact O-N 3.34Å; K246-N250 WeakPolarHBondContact O-CB 3.39Å; K246-N250 VanDerWaalsContact O-CG 3.26Å; K246-N250 PolarHBondContact O-N 2.87Å; K246-N250 VanDerWaalsContact O-N 3.14Å; K246-N250 PolarHBondContact O-ND2 3.39Å
247	L	91.3	Very high	89.9	Confident	6 Å²	6	48.4 Å²	48.4	3%	0.031	23%	0.229	C	C	.	.	H	α-helix	trans	-59.3	-49.1	172.1	171.9	64.5	0	0	0	110.5	R243 A244 R245 E249 N250 L251 A363 I364 Y367	R243-L247 PolarHBondContact O-N 2.93Å; A244-L247 WeakPolarHBondContact O-CB 3.49Å; A244-L247 PolarHBondContact O-N 3.1Å; R245-L247 VanDerWaalsContact C-N 3.27Å; R245-L247 PolarHBondContact O-N 3.18Å; L247-E249 PolarHBondContact O-N 3.44Å; L247-N250 PolarHBondContact O-N 3.38Å; L247-L251 HydrophobicContact CD1-CD1 3.74Å; L247-L251 HydrophobicContact CD1-CG 4.1Å; L247-L251 HydrophobicContact CG-CD1 4.05Å; L247-L251 VanDerWaalsContact O-CG 3.29Å; L247-L251 WeakPolarHBondContact O-CG 3.44Å; L247-L251 PolarHBondContact O-N 3.01Å; L247-L251 VanDerWaalsContact O-N 3.1Å; L247-A363 HydrophobicContact CD1-CB 3.66Å; L247-A363 WeakPolarHBondContact CD1-O 3.39Å; L247-I364 HydrophobicContact CD1-CG1 4.39Å; L247-Y367 HydrophobicContact CB-CD2 4.39Å; L247-Y367 HydrophobicContact CD2-CD1 4.12Å; L247-Y367 HydrophobicContact CD2-CD2 4.34Å; L247-Y367 HydrophobicContact CD2-CG 3.91Å
248	L	88.9	Confident	89.3	Confident	14 Å²	14	47.6 Å²	47.6	7%	0.073	23%	0.225	C	C	.	.	H	α-helix	trans	-62.8	-43.5	-179	-63	166.2	0	0	0	112.2	L197 V201 A244 R245 N250 L251 R252 V421 I425	L197-L248 HydrophobicContact CB-CD2 4.1Å; L197-L248 HydrophobicContact CD2-CD2 4.09Å; V201-L248 HydrophobicContact CG2-CD1 3.47Å; V201-L248 VanDerWaalsContact CG2-CD1 3.47Å; V201-L248 HydrophobicContact CG2-CD2 4.03Å; V201-L248 HydrophobicContact CG2-CG 4.4Å; A244-L248 WeakPolarHBondContact O-CG 3.31Å; A244-L248 PolarHBondContact O-N 3.38Å; R245-L248 WeakPolarHBondContact O-CB 3.5Å; R245-L248 PolarHBondContact O-N 2.89Å; L248-N250 VanDerWaalsContact C-N 3.33Å; L248-N250 PolarHBondContact O-N 3.31Å; L248-L251 PolarHBondContact O-N 2.97Å; L248-R252 PolarHBondContact O-N 3.38Å; L248-V421 HydrophobicContact CB-CG1 4.19Å; L248-I425 HydrophobicContact CD2-CD1 4.38Å
249	E	87.1	Confident	88.7	Confident	80 Å²	80	45.2 Å²	45.2	37%	0.374	22%	0.22	S	C	.	.	H	α-helix	trans	-57.3	-44.9	174.9	-71.5	171.6	-171.2	0	0	112.1	R245 L247 L251 R252 P253	R245-E249 PolarHBondContact O-N 3.47Å; R245-E249 VanDerWaalsContact O-N 3.08Å; L247-E249 PolarHBondContact O-N 3.44Å; E249-L251 VanDerWaalsContact C-N 3.28Å; E249-L251 PolarHBondContact O-N 3.01Å; E249-R252 PolarHBondContact O-N 3.04Å; E249-P253 WeakPolarHBondContact O-CD 3.48Å
250	N	88.6	Confident	88.3	Confident	71 Å²	71	45.4 Å²	45.4	38%	0.38	22%	0.223	S	C	.	.	H	α-helix	trans	-66.9	-29.9	179.7	-73.8	-43.8	0	0	0	112.8	K246 L247 L248 R359	K246-N250 WeakPolarHBondContact O-CB 3.39Å; K246-N250 VanDerWaalsContact O-CG 3.26Å; K246-N250 PolarHBondContact O-N 2.87Å; K246-N250 VanDerWaalsContact O-N 3.14Å; K246-N250 PolarHBondContact O-ND2 3.39Å; L247-N250 PolarHBondContact O-N 3.38Å; L248-N250 VanDerWaalsContact C-N 3.33Å; L248-N250 PolarHBondContact O-N 3.31Å; N250-R359 PolarHBondContact O-NE 3.5Å; N250-R359 PolarHBondContact O-NH2 3.11Å
251	L	90.1	Very high	87.8	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-87.7	-20.5	-179.4	-66	-176.9	0	0	0	113.4	L197 L247 L248 E249 M254 I255 F360 A363	L197-L251 HydrophobicContact CD1-CD1 4.22Å; L197-L251 HydrophobicContact CD2-CD1 3.47Å; L197-L251 VanDerWaalsContact CD2-CD1 3.47Å; L197-L251 HydrophobicContact CG-CD1 4.46Å; L247-L251 HydrophobicContact CD1-CD1 3.74Å; L247-L251 HydrophobicContact CD1-CG 4.1Å; L247-L251 HydrophobicContact CG-CD1 4.05Å; L247-L251 VanDerWaalsContact O-CG 3.29Å; L247-L251 WeakPolarHBondContact O-CG 3.44Å; L247-L251 PolarHBondContact O-N 3.01Å; L247-L251 VanDerWaalsContact O-N 3.1Å; L248-L251 PolarHBondContact O-N 2.97Å; E249-L251 VanDerWaalsContact C-N 3.28Å; E249-L251 PolarHBondContact O-N 3.01Å; L251-M254 HydrophobicContact CB-CE 4.22Å; L251-M254 HydrophobicContact CD2-CE 3.63Å; L251-M254 HydrophobicContact CG-CE 4.36Å; L251-M254 WeakPolarHBondContact O-CB 3.46Å; L251-M254 PolarHBondContact O-N 2.88Å; L251-M254 VanDerWaalsContact O-N 3.07Å; L251-I255 WeakPolarHBondContact O-CG1 3.34Å; L251-I255 PolarHBondContact O-N 3.22Å; L251-F360 HydrophobicContact CD1-CD2 3.9Å; L251-F360 HydrophobicContact CD1-CE2 4.05Å; L251-F360 HydrophobicContact CD2-CD2 3.96Å; L251-A363 HydrophobicContact CD2-CB 3.6Å; L251-A363 HydrophobicContact CG-CB 4.19Å
252	R	85.5	Confident	87.4	Confident	89 Å²	89	45.4 Å²	45.4	34%	0.336	22%	0.223	S	C	.	.	H	α-helix	trans	-52.5	-48	-179.1	179.7	-172.6	-174.9	177.3	-2.5	114	L248 E249 M254 I255 S256 E424	L248-R252 PolarHBondContact O-N 3.38Å; E249-R252 PolarHBondContact O-N 3.04Å; R252-M254 VanDerWaalsContact C-N 3.31Å; R252-M254 PolarHBondContact O-N 2.78Å; R252-I255 PolarHBondContact O-N 3.12Å; R252-S256 PolarHBondContact O-N 3.42Å; R252-E424 IonicContact CZ-OE1 3.11Å; R252-E424 IonicContact CZ-OE2 3.34Å; R252-E424 VanDerWaalsContact CZ-OE2 3.28Å; R252-E424 IonicContact NE-OE1 2.66Å; R252-E424 IonicContact NE-OE2 2.77Å; R252-E424 PolarHBondContact NE-OE2 3.42Å; R252-E424 IonicContact NH2-OE1 2.69Å; R252-E424 PolarHBondContact NH2-OE1 3.22Å; R252-E424 IonicContact NH2-OE2 3.04Å; R252-E424 PolarHBondContact NH2-OE2 2.91Å; R252-E424 VanDerWaalsContact NH2-OE2 3.17Å
253	P	86.6	Confident	87	Confident	56 Å²	56	44 Å²	44	36%	0.364	22%	0.221	S	C	.	.	H	α-helix	trans	-65.9	-34.9	179	-18.1	30.7	0	0	0	112.5	E249 I255 S256 D257 R359	E249-P253 WeakPolarHBondContact O-CD 3.48Å; P253-I255 VanDerWaalsContact C-N 3.35Å; P253-I255 PolarHBondContact O-N 3.34Å; P253-S256 PolarHBondContact O-N 3.03Å; P253-D257 VanDerWaalsContact O-CG 3.22Å; P253-D257 PolarHBondContact O-N 3.14Å; P253-R359 VanDerWaalsContact CG-NH2 3.28Å
254	M	86.7	Confident	86.7	Confident	1 Å²	1	47.1 Å²	47.1	1%	0.005	24%	0.237	C	C	.	.	H	α-helix	trans	-61.8	-43.8	176.1	174	-92.1	-69.2	0	0	111.5	L251 R252 D257 L258 Q356 F360	L251-M254 HydrophobicContact CB-CE 4.22Å; L251-M254 HydrophobicContact CD2-CE 3.63Å; L251-M254 HydrophobicContact CG-CE 4.36Å; L251-M254 WeakPolarHBondContact O-CB 3.46Å; L251-M254 PolarHBondContact O-N 2.88Å; L251-M254 VanDerWaalsContact O-N 3.07Å; R252-M254 VanDerWaalsContact C-N 3.31Å; R252-M254 PolarHBondContact O-N 2.78Å; M254-D257 PolarHBondContact O-N 2.85Å; M254-L258 HydrophobicContact CG-CD1 4.07Å; M254-L258 WeakPolarHBondContact O-CG 3.48Å; M254-L258 PolarHBondContact O-N 3.32Å; M254-L258 HydrophobicContact SD-CD1 3.44Å; M254-L258 WeakPolarHBondContact SD-CD1 3.25Å; M254-Q356 HydrophobicContact CG-CB 3.74Å; M254-Q356 HydrophobicContact CG-CG 4.11Å; M254-F360 HydrophobicContact CE-CB 3.85Å; M254-F360 HydrophobicContact CE-CD2 3.61Å; M254-F360 HydrophobicContact CE-CG 4.12Å
255	I	84.3	Confident	86.5	Confident	15 Å²	15	48.4 Å²	48.4	8%	0.077	25%	0.247	C	C	.	.	H	α-helix	trans	-61.8	-45.4	175.7	-67.3	169.9	0	0	0	110.8	M190 L197 L251 R252 P253 D257 L258 N259 I425 I428	M190-I255 HydrophobicContact CE-CG2 4.35Å; L197-I255 HydrophobicContact CD1-CD1 3.48Å; L197-I255 VanDerWaalsContact CD1-CD1 3.48Å; L197-I255 HydrophobicContact CD1-CG1 4.4Å; L251-I255 WeakPolarHBondContact O-CG1 3.34Å; L251-I255 PolarHBondContact O-N 3.22Å; R252-I255 PolarHBondContact O-N 3.12Å; P253-I255 VanDerWaalsContact C-N 3.35Å; P253-I255 PolarHBondContact O-N 3.34Å; I255-D257 PolarHBondContact O-N 3.28Å; I255-L258 PolarHBondContact O-N 3.49Å; I255-N259 WeakPolarHBondContact O-CB 3.25Å; I255-N259 PolarHBondContact O-N 3.31Å; I255-I425 HydrophobicContact CD1-CD1 4.43Å; I255-I425 HydrophobicContact CD1-CG1 4.18Å; I255-I428 HydrophobicContact CG2-CD1 3.3Å; I255-I428 HydrophobicContact CG2-CG1 4.04Å
256	S	85.1	Confident	86.4	Confident	61 Å²	61	47.2 Å²	47.2	43%	0.427	24%	0.243	S	C	.	.	H	α-helix	trans	-61	-42.8	178.7	173.9	0	0	0	0	112.5	R252 P253 N259 T260	R252-S256 PolarHBondContact O-N 3.42Å; P253-S256 PolarHBondContact O-N 3.03Å; S256-N259 PolarHBondContact O-N 3.09Å; S256-T260 WeakPolarHBondContact O-CB 3.33Å; S256-T260 PolarHBondContact O-N 3.42Å; S256-T260 PolarHBondContact O-OG1 3.33Å
257	D	84.3	Confident	86.3	Confident	69 Å²	69	43.5 Å²	43.5	37%	0.369	23%	0.231	S	C	.	.	H	α-helix	trans	-64.3	-47.6	178.6	-69	-23.1	0	0	0	111.2	P253 M254 I255 N259 T260 Y261 Q356	P253-D257 VanDerWaalsContact O-CG 3.22Å; P253-D257 PolarHBondContact O-N 3.14Å; M254-D257 PolarHBondContact O-N 2.85Å; I255-D257 PolarHBondContact O-N 3.28Å; D257-N259 PolarHBondContact O-N 3.11Å; D257-T260 WeakPolarHBondContact O-CB 2.96Å; D257-T260 PolarHBondContact O-N 3.33Å; D257-Y261 PolarHBondContact O-N 2.99Å; D257-Q356 PolarHBondContact OD2-NE2 3.16Å
258	L	82.5	Confident	86.2	Confident	18 Å²	18	47.1 Å²	47.1	9%	0.094	25%	0.251	C	S	.	.	H	α-helix	trans	-65.7	-38.9	177.8	-70.8	168.4	0	0	0	112	M190 M254 I255 T260 Y261 L262 Q356	M190-L258 HydrophobicContact CE-CB 3.88Å; M190-L258 HydrophobicContact CE-CD1 4.34Å; M190-L258 HydrophobicContact CG-CB 4.42Å; M190-L258 HydrophobicContact SD-CB 3.66Å; M190-L258 HydrophobicContact SD-CD1 3.37Å; M190-L258 WeakPolarHBondContact SD-CD1 3.4Å; M190-L258 HydrophobicContact SD-CG 4.1Å; M254-L258 HydrophobicContact CG-CD1 4.07Å; M254-L258 WeakPolarHBondContact O-CG 3.48Å; M254-L258 PolarHBondContact O-N 3.32Å; M254-L258 HydrophobicContact SD-CD1 3.44Å; M254-L258 WeakPolarHBondContact SD-CD1 3.25Å; I255-L258 PolarHBondContact O-N 3.49Å; L258-T260 VanDerWaalsContact C-N 3.33Å; L258-T260 PolarHBondContact O-N 2.84Å; L258-Y261 WeakPolarHBondContact O-CB 3.4Å; L258-Y261 PolarHBondContact O-N 3.39Å; L258-L262 WeakPolarHBondContact O-CB 3.21Å; L258-L262 WeakPolarHBondContact O-CG 3.28Å; L258-L262 PolarHBondContact O-N 3.48Å; L258-Q356 HydrophobicContact CD1-CB 4.14Å; L258-Q356 HydrophobicContact CD1-CG 4.44Å; L258-Q356 HydrophobicContact CD2-CB 4.4Å; L258-Q356 HydrophobicContact CD2-CG 4.22Å; L258-Q356 HydrophobicContact CG-CB 4.39Å; L258-Q356 HydrophobicContact CG-CG 4.18Å
259	N	82.8	Confident	86.2	Confident	48 Å²	48	47 Å²	47	26%	0.257	25%	0.25	S	S	.	.	H	α-helix	trans	-61.2	-43.2	174.4	-172.2	44	0	0	0	111.2	I255 S256 D257 Y261 L262 N263	I255-N259 WeakPolarHBondContact O-CB 3.25Å; I255-N259 PolarHBondContact O-N 3.31Å; S256-N259 PolarHBondContact O-N 3.09Å; D257-N259 PolarHBondContact O-N 3.11Å; N259-Y261 VanDerWaalsContact C-N 3.35Å; N259-Y261 PolarHBondContact O-N 3.38Å; N259-L262 PolarHBondContact O-N 2.92Å; N259-N263 VanDerWaalsContact O-CB 3.31Å; N259-N263 WeakPolarHBondContact O-CB 3.35Å; N259-N263 PolarHBondContact O-N 3.17Å; N259-N263 PolarHBondContact OD1-ND2 3.2Å
260	T	86.3	Confident	86.2	Confident	53 Å²	53	46.9 Å²	46.9	33%	0.325	25%	0.246	S	C	.	.	H	α-helix	trans	-62.3	-41.9	175.4	-65.6	0	0	0	0	111.7	S256 D257 L258 K264 A265	S256-T260 WeakPolarHBondContact O-CB 3.33Å; S256-T260 PolarHBondContact O-N 3.42Å; S256-T260 PolarHBondContact O-OG1 3.33Å; D257-T260 WeakPolarHBondContact O-CB 2.96Å; D257-T260 PolarHBondContact O-N 3.33Å; L258-T260 VanDerWaalsContact C-N 3.33Å; L258-T260 PolarHBondContact O-N 2.84Å; T260-K264 HydrophobicContact CG2-CD 4.33Å; T260-K264 WeakPolarHBondContact O-CA 3.47Å; T260-K264 VanDerWaalsContact O-CB 3.29Å; T260-K264 WeakPolarHBondContact O-CB 3.42Å; T260-K264 PolarHBondContact O-N 3Å; T260-A265 PolarHBondContact O-N 2.9Å
261	Y	84.2	Confident	86.3	Confident	13 Å²	13	45.5 Å²	45.5	5%	0.051	25%	0.245	C	C	.	.	I	π-helix	trans	-61.1	-52	175.5	175.9	-98.6	0	0	0	111.8	Y186 D257 L258 N259 A265 V266 L345 R349	Y186-Y261 HydrophobicContact CD2-CE1 4.16Å; Y186-Y261 HydrophobicContact CE2-CE1 4.47Å; D257-Y261 PolarHBondContact O-N 2.99Å; L258-Y261 WeakPolarHBondContact O-CB 3.4Å; L258-Y261 PolarHBondContact O-N 3.39Å; N259-Y261 VanDerWaalsContact C-N 3.35Å; N259-Y261 PolarHBondContact O-N 3.38Å; Y261-A265 HydrophobicContact CD2-CB 4.32Å; Y261-A265 WeakPolarHBondContact O-CB 3.45Å; Y261-A265 PolarHBondContact O-N 3.01Å; Y261-V266 HydrophobicContact CD1-CG2 4.29Å; Y261-V266 HydrophobicContact CE1-CG2 3.83Å; Y261-V266 HydrophobicContact CE2-CG2 4.36Å; Y261-V266 PolarHBondContact O-N 2.94Å; Y261-L345 HydrophobicContact CD2-CD1 4.24Å; Y261-L345 HydrophobicContact CE2-CD1 3.58Å; Y261-L345 HydrophobicContact CE2-CG 4.22Å; Y261-R349 HydrophobicContact CE2-CB 4.35Å; Y261-R349 WeakPolarHBondContact OH-CD 3.38Å; Y261-R349 WeakPolarHBondContact OH-CG 3.47Å
262	L	84.1	Confident	86.3	Confident	13 Å²	13	46.1 Å²	46.1	7%	0.068	25%	0.249	C	C	.	.	I	π-helix	trans	-68.3	-41.5	-176.3	-75.1	175.7	0	0	0	113.6	T183 M190 L258 N259 P267	T183-L262 HydrophobicContact CG2-CD2 4.17Å; M190-L262 HydrophobicContact CB-CD1 4.18Å; M190-L262 HydrophobicContact CG-CD1 3.63Å; L258-L262 WeakPolarHBondContact O-CB 3.21Å; L258-L262 WeakPolarHBondContact O-CG 3.28Å; L258-L262 PolarHBondContact O-N 3.48Å; N259-L262 PolarHBondContact O-N 2.92Å; L262-P267 WeakPolarHBondContact O-CD 3.47Å
263	N	85.4	Confident	86.4	Confident	90 Å²	90	42 Å²	42	48%	0.481	23%	0.233	S	C	.	.	I	π-helix	trans	-101	-8.9	-170.5	-70.9	-32.4	0	0	0	114.2	N259	N259-N263 VanDerWaalsContact O-CB 3.31Å; N259-N263 WeakPolarHBondContact O-CB 3.35Å; N259-N263 PolarHBondContact O-N 3.17Å; N259-N263 PolarHBondContact OD1-ND2 3.2Å
264	K	87.5	Confident	86.4	Confident	146 Å²	146	45.2 Å²	45.2	64%	0.635	24%	0.242	S	C	*	.	I	π-helix	trans	-123.9	-55.8	175.8	-56.8	-178	-179	170	0	113	T260 D268	T260-K264 HydrophobicContact CG2-CD 4.33Å; T260-K264 WeakPolarHBondContact O-CA 3.47Å; T260-K264 VanDerWaalsContact O-CB 3.29Å; T260-K264 WeakPolarHBondContact O-CB 3.42Å; T260-K264 PolarHBondContact O-N 3Å; K264-D268 WeakPolarHBondContact O-CB 3.39Å; K264-D268 PolarHBondContact O-N 2.77Å; K264-D268 VanDerWaalsContact O-N 3.11Å
265	A	86.5	Confident	86.6	Confident	28 Å²	28	51.7 Å²	51.7	23%	0.231	27%	0.27	C	S	.	.	I	π-helix	trans	-68.6	-46.4	-172.6	0	0	0	0	0	113.2	T260 Y261 T269 L345	T260-A265 PolarHBondContact O-N 2.9Å; Y261-A265 HydrophobicContact CD2-CB 4.32Å; Y261-A265 WeakPolarHBondContact O-CB 3.45Å; Y261-A265 PolarHBondContact O-N 3.01Å; A265-T269 PolarHBondContact O-N 3.12Å; A265-T269 PolarHBondContact O-OG1 3.14Å; A265-L345 HydrophobicContact CB-CD1 3.93Å
266	V	86.4	Confident	86.9	Confident	2 Å²	2	51.2 Å²	51.2	1%	0.012	27%	0.267	C	S	.	.	H	α-helix	trans	-65.9	-48	178	172	0	0	0	0	111.7	T183 Y261 D268 T269 R270 L345	T183-V266 HydrophobicContact CG2-CG1 3.87Å; T183-V266 WeakPolarHBondContact OG1-CG1 2.97Å; Y261-V266 HydrophobicContact CD1-CG2 4.29Å; Y261-V266 HydrophobicContact CE1-CG2 3.83Å; Y261-V266 HydrophobicContact CE2-CG2 4.36Å; Y261-V266 PolarHBondContact O-N 2.94Å; V266-D268 PolarHBondContact O-N 3.02Å; V266-T269 PolarHBondContact O-N 2.95Å; V266-R270 WeakPolarHBondContact O-CB 3.48Å; V266-R270 PolarHBondContact O-N 3.13Å; V266-L345 HydrophobicContact CG2-CD2 4.43Å
267	P	87.7	Confident	86.9	Confident	40 Å²	40	49.3 Å²	49.3	26%	0.26	25%	0.252	S	S	.	.	H	α-helix	trans	-59.5	-38.5	176.3	-27.8	36.2	0	0	0	114.3	L262 R270 A271	L262-P267 WeakPolarHBondContact O-CD 3.47Å; P267-R270 PolarHBondContact O-N 2.84Å; P267-A271 WeakPolarHBondContact O-CB 3.42Å; P267-A271 PolarHBondContact O-N 3.37Å
268	D	89.8	Confident	87.1	Confident	83 Å²	83	49 Å²	49	44%	0.444	25%	0.25	S	S	.	.	H	α-helix	trans	-63.8	-45.1	176.5	179.1	69.1	0	0	0	112.2	K264 V266 R270 A271 T272 K341	K264-D268 WeakPolarHBondContact O-CB 3.39Å; K264-D268 PolarHBondContact O-N 2.77Å; K264-D268 VanDerWaalsContact O-N 3.11Å; V266-D268 PolarHBondContact O-N 3.02Å; D268-R270 VanDerWaalsContact C-N 3.34Å; D268-R270 PolarHBondContact O-N 3.48Å; D268-A271 PolarHBondContact O-N 2.81Å; D268-T272 PolarHBondContact O-N 3.05Å; D268-T272 PolarHBondContact O-OG1 3.36Å; D268-K341 IonicContact OD1-NZ 2.63Å; D268-K341 IonicContact OD2-NZ 3.04Å; D268-K341 PolarHBondContact OD2-NZ 3.42Å
269	T	89	Confident	87.4	Confident	10 Å²	10	48.2 Å²	48.2	6%	0.061	25%	0.246	C	C	.	.	H	α-helix	trans	-61.5	-45.2	176.1	-53.6	0	0	0	0	110.5	L179 A265 V266 A271 T272 L273 K341 L342 L345	L179-T269 HydrophobicContact CD2-CG2 4.15Å; A265-T269 PolarHBondContact O-N 3.12Å; A265-T269 PolarHBondContact O-OG1 3.14Å; V266-T269 PolarHBondContact O-N 2.95Å; T269-A271 PolarHBondContact O-N 3.16Å; T269-T272 PolarHBondContact O-N 3.01Å; T269-L273 PolarHBondContact O-N 3.32Å; T269-K341 HydrophobicContact CG2-CB 4.42Å; T269-L342 HydrophobicContact CG2-CD2 3.8Å; T269-L342 HydrophobicContact CG2-CG 4.31Å; T269-L345 HydrophobicContact CG2-CD2 4.08Å
270	R	87.4	Confident	87.6	Confident	78 Å²	78	46.2 Å²	46.2	29%	0.294	24%	0.235	S	C	.	.	H	α-helix	trans	-59.9	-43.5	175.6	-162.6	-167.4	-33.3	162.2	9.3	112.2	L176 V266 P267 D268 T272 L273 K274	L176-R270 HydrophobicContact CD1-CG 4.25Å; V266-R270 WeakPolarHBondContact O-CB 3.48Å; V266-R270 PolarHBondContact O-N 3.13Å; P267-R270 PolarHBondContact O-N 2.84Å; D268-R270 VanDerWaalsContact C-N 3.34Å; D268-R270 PolarHBondContact O-N 3.48Å; R270-T272 VanDerWaalsContact C-N 3.32Å; R270-T272 PolarHBondContact O-N 3.38Å; R270-L273 PolarHBondContact O-N 3.06Å; R270-K274 WeakPolarHBondContact O-CG 3.39Å; R270-K274 PolarHBondContact O-N 3.44Å
271	A	90	Very high	87.7	Confident	43 Å²	43	44.2 Å²	44.2	36%	0.355	22%	0.222	S	C	.	.	H	α-helix	trans	-64.4	-39.1	178.1	0	0	0	0	0	111.6	P267 D268 T269 K274 K275	P267-A271 WeakPolarHBondContact O-CB 3.42Å; P267-A271 PolarHBondContact O-N 3.37Å; D268-A271 PolarHBondContact O-N 2.81Å; T269-A271 PolarHBondContact O-N 3.16Å; A271-K274 PolarHBondContact O-N 3.37Å; A271-K275 WeakPolarHBondContact O-CG 3.46Å; A271-K275 PolarHBondContact O-N 3.22Å; A271-K275 VanDerWaalsContact O-N 3.12Å
272	T	90.3	Very high	88	Confident	12 Å²	12	44.3 Å²	44.3	7%	0.074	22%	0.223	C	C	.	.	H	α-helix	trans	-65.1	-42.7	176.2	-52.7	0	0	0	0	111.1	D268 T269 R270 K275 Y276 V338 K341	D268-T272 PolarHBondContact O-N 3.05Å; D268-T272 PolarHBondContact O-OG1 3.36Å; T269-T272 PolarHBondContact O-N 3.01Å; R270-T272 VanDerWaalsContact C-N 3.32Å; R270-T272 PolarHBondContact O-N 3.38Å; T272-K275 WeakPolarHBondContact O-CB 3.15Å; T272-K275 PolarHBondContact O-N 3.37Å; T272-Y276 PolarHBondContact O-N 2.59Å; T272-V338 HydrophobicContact CG2-CG2 3.92Å; T272-K341 HydrophobicContact CG2-CD 3.93Å; T272-K341 PolarHBondContact OG1-NZ 3.49Å
273	L	87.1	Confident	88.2	Confident	2 Å²	2	45.4 Å²	45.4	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-67.5	-37.2	176.7	-172.6	64.1	0	0	0	113	L172 L176 T269 R270 K275 Y276 L277 V338	L172-L273 HydrophobicContact CB-CD1 4.05Å; L176-L273 HydrophobicContact CB-CD2 3.39Å; L176-L273 HydrophobicContact CD1-CD2 3.47Å; L176-L273 VanDerWaalsContact CD1-CD2 3.47Å; L176-L273 HydrophobicContact CD2-CD2 3.73Å; L176-L273 HydrophobicContact CD2-CG 4.42Å; L176-L273 HydrophobicContact CG-CD2 3.65Å; T269-L273 PolarHBondContact O-N 3.32Å; R270-L273 PolarHBondContact O-N 3.06Å; L273-K275 VanDerWaalsContact C-N 3.29Å; L273-K275 PolarHBondContact O-N 3.49Å; L273-Y276 HydrophobicContact CD1-CD1 3.6Å; L273-Y276 HydrophobicContact CD1-CE1 4.33Å; L273-Y276 HydrophobicContact CD1-CG 4.34Å; L273-Y276 WeakPolarHBondContact O-CB 2.98Å; L273-Y276 PolarHBondContact O-N 3.01Å; L273-Y276 VanDerWaalsContact O-N 3.14Å; L273-L277 WeakPolarHBondContact O-CG 3.46Å; L273-L277 PolarHBondContact O-N 2.73Å; L273-V338 HydrophobicContact CB-CG2 4.39Å; L273-V338 HydrophobicContact CD1-CB 4.42Å; L273-V338 HydrophobicContact CD1-CG1 3.52Å; L273-V338 HydrophobicContact CD1-CG2 4.02Å
274	K	86.8	Confident	88.3	Confident	125 Å²	125	41.8 Å²	41.8	54%	0.543	21%	0.207	S	C	.	.	H	α-helix	trans	-58.9	-39.6	171.7	-76.3	179.8	178.7	-175.6	0	112.2	R270 A271 L277 D278	R270-K274 WeakPolarHBondContact O-CG 3.39Å; R270-K274 PolarHBondContact O-N 3.44Å; A271-K274 PolarHBondContact O-N 3.37Å; K274-L277 PolarHBondContact O-N 3.1Å; K274-D278 WeakPolarHBondContact O-CB 3.43Å; K274-D278 PolarHBondContact O-N 2.72Å
275	K	91.3	Very high	88.4	Confident	137 Å²	137	34.8 Å²	34.8	60%	0.596	18%	0.177	S	C	*	.	H	α-helix	trans	-64.7	-40.9	174.2	-69	172.3	-177.7	176.5	0	111.7	A271 T272 L273 A279	A271-K275 WeakPolarHBondContact O-CG 3.46Å; A271-K275 PolarHBondContact O-N 3.22Å; A271-K275 VanDerWaalsContact O-N 3.12Å; T272-K275 WeakPolarHBondContact O-CB 3.15Å; T272-K275 PolarHBondContact O-N 3.37Å; L273-K275 VanDerWaalsContact C-N 3.29Å; L273-K275 PolarHBondContact O-N 3.49Å; K275-A279 WeakPolarHBondContact O-CB 3.48Å; K275-A279 PolarHBondContact O-N 3.14Å
276	Y	89.8	Confident	88.6	Confident	4 Å²	4	33.8 Å²	33.8	2%	0.016	17%	0.167	C	C	.	.	H	α-helix	trans	-60.4	-50.7	173.9	162.1	-100.4	0	0	0	111.8	D170 L172 T272 L273 D278 A279 K280 L334 R335 V338	D170-Y276 PolarHBondContact OD1-OH 3.38Å; D170-Y276 VanDerWaalsContact OD1-OH 3.1Å; D170-Y276 WeakPolarHBondContact OD2-CE1 3.48Å; D170-Y276 PolarHBondContact OD2-OH 3.19Å; L172-Y276 HydrophobicContact CB-CE1 4.09Å; L172-Y276 HydrophobicContact CD1-CD1 4.02Å; L172-Y276 HydrophobicContact CD1-CE1 3.49Å; L172-Y276 VanDerWaalsContact CD1-CE1 3.49Å; L172-Y276 HydrophobicContact CD1-CE2 4.16Å; L172-Y276 HydrophobicContact CG-CE1 4.41Å; T272-Y276 PolarHBondContact O-N 2.59Å; L273-Y276 HydrophobicContact CD1-CD1 3.6Å; L273-Y276 HydrophobicContact CD1-CE1 4.33Å; L273-Y276 HydrophobicContact CD1-CG 4.34Å; L273-Y276 WeakPolarHBondContact O-CB 2.98Å; L273-Y276 PolarHBondContact O-N 3.01Å; L273-Y276 VanDerWaalsContact O-N 3.14Å; Y276-D278 VanDerWaalsContact C-N 3.3Å; Y276-D278 PolarHBondContact O-N 3.14Å; Y276-A279 PolarHBondContact O-N 2.85Å; Y276-A279 VanDerWaalsContact O-N 3.13Å; Y276-K280 HydrophobicContact CE1-CD 4.4Å; Y276-K280 WeakPolarHBondContact O-CB 3.29Å; Y276-K280 PolarHBondContact O-N 3.22Å; Y276-L334 HydrophobicContact CD2-CB 4.23Å; Y276-R335 HydrophobicContact CD2-CB 4.04Å; Y276-R335 HydrophobicContact CE2-CB 3.68Å; Y276-R335 HydrophobicContact CE2-CG 4.17Å; Y276-V338 HydrophobicContact CG-CG2 4.25Å
277	L	85.7	Confident	88.7	Confident	22 Å²	22	34.9 Å²	34.9	12%	0.115	17%	0.174	C	C	.	.	H	α-helix	trans	-60.1	-41.7	179.5	-68.1	175.3	0	0	0	111.5	V173 L176 L273 K274 A279 K280 F281	V173-L277 HydrophobicContact CG2-CD2 3.7Å; L176-L277 HydrophobicContact CD2-CD1 4.34Å; L273-L277 WeakPolarHBondContact O-CG 3.46Å; L273-L277 PolarHBondContact O-N 2.73Å; K274-L277 PolarHBondContact O-N 3.1Å; L277-A279 VanDerWaalsContact C-N 3.35Å; L277-A279 PolarHBondContact O-N 3.1Å; L277-K280 HydrophobicContact CD2-CD 4.45Å; L277-K280 WeakPolarHBondContact O-CB 3.26Å; L277-K280 PolarHBondContact O-N 2.82Å; L277-F281 HydrophobicContact CB-CE2 4Å; L277-F281 HydrophobicContact CB-CZ 4.35Å; L277-F281 WeakPolarHBondContact O-CD2 3.39Å; L277-F281 WeakPolarHBondContact O-CG 3.46Å; L277-F281 PolarHBondContact O-N 2.95Å
278	D	87.8	Confident	88.7	Confident	62 Å²	62	33.7 Å²	33.7	33%	0.332	17%	0.166	S	C	.	.	H	α-helix	trans	-60.6	-42.4	175.4	-171.5	72.9	0	0	0	112.7	K143 K274 Y276 F281 E282	K143-D278 VanDerWaalsContact CE-O 3.29Å; K143-D278 WeakPolarHBondContact CE-O 3.04Å; K143-D278 WeakPolarHBondContact CE-OD1 3.45Å; K143-D278 IonicContact NZ-OD1 3.05Å; K143-D278 PolarHBondContact NZ-OD1 3.4Å; K143-D278 IonicContact NZ-OD2 2.64Å; K143-D278 PolarHBondContact NZ-OD2 3.47Å; K274-D278 WeakPolarHBondContact O-CB 3.43Å; K274-D278 PolarHBondContact O-N 2.72Å; Y276-D278 VanDerWaalsContact C-N 3.3Å; Y276-D278 PolarHBondContact O-N 3.14Å; D278-F281 PolarHBondContact O-N 2.81Å; D278-E282 WeakPolarHBondContact O-CB 3.44Å; D278-E282 PolarHBondContact O-N 3.06Å
279	A	90.4	Very high	88.6	Confident	1 Å²	1	31.7 Å²	31.7	1%	0.008	15%	0.153	C	C	.	.	H	α-helix	trans	-68.9	-36.2	175.6	0	0	0	0	0	112.6	K275 Y276 L277 E282 Y283 K330 F331 L334	K275-A279 WeakPolarHBondContact O-CB 3.48Å; K275-A279 PolarHBondContact O-N 3.14Å; Y276-A279 PolarHBondContact O-N 2.85Å; Y276-A279 VanDerWaalsContact O-N 3.13Å; L277-A279 VanDerWaalsContact C-N 3.35Å; L277-A279 PolarHBondContact O-N 3.1Å; A279-E282 PolarHBondContact O-N 3.43Å; A279-Y283 PolarHBondContact O-N 2.92Å; A279-K330 HydrophobicContact CB-CD 4.42Å; A279-K330 HydrophobicContact CB-CG 4.37Å; A279-F331 HydrophobicContact CB-CB 4.2Å; A279-L334 HydrophobicContact CB-CD1 3.57Å
280	K	86.6	Confident	88.7	Confident	7 Å²	7	31.5 Å²	31.5	3%	0.03	15%	0.152	C	C	.	.	H	α-helix	trans	-60.9	-48.2	172.8	174.6	-174	176.1	-172.2	0	110.9	E150 L167 D170 Y276 L277 E282 Y283 L284	E150-K280 IonicContact OE1-NZ 3.34Å; E150-K280 PolarHBondContact OE1-NZ 3.43Å; L167-K280 HydrophobicContact CD1-CD 4.07Å; L167-K280 VanDerWaalsContact CD1-CE 3.45Å; L167-K280 HydrophobicContact CD1-CG 3.66Å; D170-K280 VanDerWaalsContact OD2-CD 3.25Å; D170-K280 WeakPolarHBondContact OD2-CD 3.45Å; D170-K280 VanDerWaalsContact OD2-CE 3.28Å; D170-K280 WeakPolarHBondContact OD2-CE 3.27Å; D170-K280 IonicContact OD2-NZ 2.74Å; D170-K280 PolarHBondContact OD2-NZ 2.96Å; Y276-K280 HydrophobicContact CE1-CD 4.4Å; Y276-K280 WeakPolarHBondContact O-CB 3.29Å; Y276-K280 PolarHBondContact O-N 3.22Å; L277-K280 HydrophobicContact CD2-CD 4.45Å; L277-K280 WeakPolarHBondContact O-CB 3.26Å; L277-K280 PolarHBondContact O-N 2.82Å; K280-E282 VanDerWaalsContact C-N 3.32Å; K280-E282 PolarHBondContact O-N 3Å; K280-Y283 PolarHBondContact O-N 3.29Å; K280-L284 HydrophobicContact CG-CD1 4.29Å; K280-L284 WeakPolarHBondContact O-CG 3.35Å; K280-L284 PolarHBondContact O-N 3.23Å
281	F	88.2	Confident	88.8	Confident	11 Å²	11	30 Å²	30	5%	0.048	15%	0.147	C	C	.	.	H	α-helix	trans	-65	-36.4	178.3	-59.4	-38.8	0	0	0	112.7	K143 H146 K147 E150 L277 D278 L284 S285	K143-F281 HydrophobicContact CG-CB 3.81Å; H146-F281 HydrophobicContact CB-CB 4.13Å; H146-F281 HydrophobicContact CB-CD1 3.58Å; H146-F281 HydrophobicContact CB-CE1 4.28Å; H146-F281 HydrophobicContact CB-CG 4.06Å; K147-F281 HydrophobicContact CB-CD2 3.94Å; K147-F281 HydrophobicContact CB-CE2 3.97Å; K147-F281 HydrophobicContact CG-CD2 4.28Å; K147-F281 HydrophobicContact CG-CE2 4.01Å; E150-F281 HydrophobicContact CB-CE1 3.78Å; E150-F281 HydrophobicContact CB-CZ 3.57Å; E150-F281 HydrophobicContact CG-CE1 3.9Å; E150-F281 HydrophobicContact CG-CZ 3.74Å; E150-F281 WeakPolarHBondContact OE2-CE1 3.4Å; L277-F281 HydrophobicContact CB-CE2 4Å; L277-F281 HydrophobicContact CB-CZ 4.35Å; L277-F281 WeakPolarHBondContact O-CD2 3.39Å; L277-F281 WeakPolarHBondContact O-CG 3.46Å; L277-F281 PolarHBondContact O-N 2.95Å; D278-F281 PolarHBondContact O-N 2.81Å; F281-L284 PolarHBondContact O-N 2.81Å; F281-S285 PolarHBondContact O-N 3.23Å; F281-S285 PolarHBondContact O-OG 2.61Å
282	E	89.7	Confident	88.8	Confident	15 Å²	15	29.7 Å²	29.7	7%	0.07	14%	0.139	C	C	.	.	H	α-helix	trans	-63.6	-41.8	172.7	-177.1	172.2	-142.8	0	0	111.5	K135 K143 D278 A279 K280 S285 Y286 K330	K135-E282 WeakPolarHBondContact CE-OE1 3.49Å; K135-E282 IonicContact NZ-OE1 2.71Å; K135-E282 PolarHBondContact NZ-OE1 3.32Å; K143-E282 HydrophobicContact CD-CB 4.32Å; D278-E282 WeakPolarHBondContact O-CB 3.44Å; D278-E282 PolarHBondContact O-N 3.06Å; A279-E282 PolarHBondContact O-N 3.43Å; K280-E282 VanDerWaalsContact C-N 3.32Å; K280-E282 PolarHBondContact O-N 3Å; E282-S285 PolarHBondContact O-OG 2.8Å; E282-Y286 HydrophobicContact CG-CD2 4.49Å; E282-Y286 HydrophobicContact CG-CE2 3.86Å; E282-Y286 WeakPolarHBondContact O-CD2 3.47Å; E282-Y286 PolarHBondContact O-N 3.34Å; E282-K330 IonicContact OE2-NZ 3.33Å; E282-K330 PolarHBondContact OE2-NZ 2.96Å
283	Y	89.3	Confident	88.9	Confident	35 Å²	35	29.5 Å²	29.5	14%	0.137	14%	0.137	C	C	.	.	H	α-helix	trans	-65.4	-45.5	174.1	171.4	-110.1	0	0	0	112.6	A279 K280 S285 Y286 C287 R324 A327 K328 F331	A279-Y283 PolarHBondContact O-N 2.92Å; K280-Y283 PolarHBondContact O-N 3.29Å; Y283-S285 VanDerWaalsContact C-N 3.32Å; Y283-S285 PolarHBondContact O-N 2.82Å; Y283-Y286 PolarHBondContact O-N 3.07Å; Y283-C287 PolarHBondContact O-N 3.46Å; Y283-C287 PolarHBondContact O-SG 3.33Å; Y283-R324 HydrophobicContact CD2-CG 4.11Å; Y283-R324 HydrophobicContact CE2-CG 3.73Å; Y283-A327 HydrophobicContact CD2-CB 4.32Å; Y283-K328 HydrophobicContact CD2-CB 3.94Å; Y283-K328 HydrophobicContact CE2-CB 3.66Å; Y283-K328 HydrophobicContact CE2-CD 4.36Å; Y283-K328 HydrophobicContact CE2-CG 4.18Å; Y283-F331 AromaticContact CD1-CD1 3.67Å; Y283-F331 HydrophobicContact CD1-CD1 3.67Å; Y283-F331 AromaticContact CD1-CE1 3.38Å; Y283-F331 HydrophobicContact CD1-CE1 3.38Å; Y283-F331 HydrophobicContact CD1-CZ 4.27Å; Y283-F331 AromaticContact CD2-CD1 3.93Å; Y283-F331 HydrophobicContact CD2-CD1 3.93Å; Y283-F331 AromaticContact CD2-CE1 3.75Å; Y283-F331 HydrophobicContact CD2-CE1 3.75Å; Y283-F331 HydrophobicContact CE1-CD1 4.27Å; Y283-F331 AromaticContact CE1-CE1 3.5Å; Y283-F331 HydrophobicContact CE1-CE1 3.5Å; Y283-F331 HydrophobicContact CE1-CZ 4.12Å; Y283-F331 HydrophobicContact CE2-CD1 4.5Å; Y283-F331 AromaticContact CE2-CE1 3.86Å; Y283-F331 HydrophobicContact CE2-CE1 3.86Å; Y283-F331 AromaticContact CG-CD1 3.46Å; Y283-F331 HydrophobicContact CG-CD1 3.46Å; Y283-F331 VanDerWaalsContact CG-CD1 3.46Å; Y283-F331 AromaticContact CG-CE1 3.5Å; Y283-F331 HydrophobicContact CG-CE1 3.5Å; Y283-F331 AromaticContact CZ-CE1 3.74Å
284	L	87	Confident	89.1	Confident	14 Å²	14	32.3 Å²	32.3	7%	0.073	15%	0.152	C	C	.	.	H	α-helix	trans	-61.1	-39.2	179.1	-77	-179.9	0	0	0	112.6	A165 L167 K280 F281 Y286 C287 L288	A165-L284 HydrophobicContact CB-CD1 4.39Å; A165-L284 HydrophobicContact CB-CD2 4.47Å; L167-L284 HydrophobicContact CD1-CD1 3.91Å; L167-L284 HydrophobicContact CD1-CD2 3.5Å; L167-L284 VanDerWaalsContact CD1-CD2 3.5Å; L167-L284 HydrophobicContact CD1-CG 3.71Å; L167-L284 HydrophobicContact CG-CD2 3.83Å; K280-L284 HydrophobicContact CG-CD1 4.29Å; K280-L284 WeakPolarHBondContact O-CG 3.35Å; K280-L284 PolarHBondContact O-N 3.23Å; F281-L284 PolarHBondContact O-N 2.81Å; L284-Y286 VanDerWaalsContact C-N 3.31Å; L284-Y286 PolarHBondContact O-N 3.01Å; L284-C287 PolarHBondContact O-N 3.05Å; L284-L288 WeakPolarHBondContact O-CB 3.04Å; L284-L288 PolarHBondContact O-N 3.49Å
285	S	88.6	Confident	89.3	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-64.4	-37.5	178.6	60.7	0	0	0	0	112.1	F281 E282 Y283 K289	F281-S285 PolarHBondContact O-N 3.23Å; F281-S285 PolarHBondContact O-OG 2.61Å; E282-S285 PolarHBondContact O-OG 2.8Å; Y283-S285 VanDerWaalsContact C-N 3.32Å; Y283-S285 PolarHBondContact O-N 2.82Å; S285-K289 PolarHBondContact O-N 2.95Å
286	Y	90.9	Very high	89.3	Confident	6 Å²	6	27.4 Å²	27.4	2%	0.024	14%	0.136	C	C	.	.	H	α-helix	trans	-65.7	-44.5	172.1	-70.1	-56	0	0	0	112.5	G134 I139 E282 Y283 L284 L288 K289 I290 L320 C323 A327	G134-Y286 WeakPolarHBondContact O-CE1 3.44Å; G134-Y286 PolarHBondContact O-OH 3.45Å; I139-Y286 HydrophobicContact CD1-CD1 3.76Å; I139-Y286 HydrophobicContact CD1-CE1 4.01Å; I139-Y286 HydrophobicContact CG1-CD1 4.31Å; I139-Y286 HydrophobicContact CG1-CE1 4.04Å; I139-Y286 HydrophobicContact CG2-CD1 4.4Å; I139-Y286 HydrophobicContact CG2-CE1 3.88Å; E282-Y286 HydrophobicContact CG-CD2 4.49Å; E282-Y286 HydrophobicContact CG-CE2 3.86Å; E282-Y286 WeakPolarHBondContact O-CD2 3.47Å; E282-Y286 PolarHBondContact O-N 3.34Å; Y283-Y286 PolarHBondContact O-N 3.07Å; L284-Y286 VanDerWaalsContact C-N 3.31Å; L284-Y286 PolarHBondContact O-N 3.01Å; Y286-L288 VanDerWaalsContact C-N 3.31Å; Y286-L288 PolarHBondContact O-N 2.88Å; Y286-K289 PolarHBondContact O-N 3.22Å; Y286-I290 WeakPolarHBondContact O-CB 3.19Å; Y286-I290 WeakPolarHBondContact O-CG1 3.48Å; Y286-I290 PolarHBondContact O-N 2.89Å; Y286-L320 HydrophobicContact CD1-CD2 3.77Å; Y286-L320 HydrophobicContact CE1-CD2 3.99Å; Y286-C323 HydrophobicContact CD1-CB 4.01Å; Y286-C323 HydrophobicContact CD2-CB 4.34Å; Y286-C323 HydrophobicContact CE1-CB 3.57Å; Y286-C323 HydrophobicContact CE2-CB 3.93Å; Y286-C323 HydrophobicContact CG-CB 4.4Å; Y286-A327 HydrophobicContact CD2-CB 3.86Å; Y286-A327 HydrophobicContact CE2-CB 4.12Å
287	C	89.8	Confident	89.4	Confident	25 Å²	25	29.7 Å²	29.7	17%	0.169	15%	0.146	C	C	.	.	H	α-helix	trans	-58.1	-44.8	176	-69.5	0	0	0	0	111.8	Y283 L284 I290 K291	Y283-C287 PolarHBondContact O-N 3.46Å; Y283-C287 PolarHBondContact O-SG 3.33Å; L284-C287 PolarHBondContact O-N 3.05Å; C287-I290 PolarHBondContact O-N 3.25Å; C287-K291 WeakPolarHBondContact O-CB 3.43Å; C287-K291 PolarHBondContact O-N 3.42Å
288	L	86.7	Confident	89.6	Confident	15 Å²	15	31.6 Å²	31.6	8%	0.079	17%	0.165	C	C	.	.	H	α-helix	trans	-64.6	-43	179.2	-175.4	62.7	0	0	0	111.7	Y19 K142 L284 Y286 K291 E292	Y19-L288 HydrophobicContact CE1-CD1 4.24Å; K142-L288 HydrophobicContact CD-CD2 4.32Å; K142-L288 HydrophobicContact CG-CD2 4.19Å; L284-L288 WeakPolarHBondContact O-CB 3.04Å; L284-L288 PolarHBondContact O-N 3.49Å; Y286-L288 VanDerWaalsContact C-N 3.31Å; Y286-L288 PolarHBondContact O-N 2.88Å; L288-K291 PolarHBondContact O-N 2.9Å; L288-E292 WeakPolarHBondContact O-CG 3.38Å; L288-E292 PolarHBondContact O-N 3.4Å
289	K	88.5	Confident	89.9	Confident	41 Å²	41	31.2 Å²	31.2	18%	0.178	17%	0.171	C	C	.	.	H	α-helix	trans	-65.2	-43.2	177.8	-177.3	55.8	169.5	-165.1	0	112.6	D138 I139 K142 S285 Y286 K291 E292 M293 L320	D138-K289 VanDerWaalsContact OD2-CD 3.24Å; D138-K289 WeakPolarHBondContact OD2-CD 3.38Å; D138-K289 WeakPolarHBondContact OD2-CE 3.34Å; D138-K289 IonicContact OD2-NZ 3.28Å; D138-K289 PolarHBondContact OD2-NZ 2.91Å; I139-K289 HydrophobicContact CD1-CB 3.65Å; I139-K289 HydrophobicContact CD1-CG 4.04Å; K142-K289 HydrophobicContact CD-CB 4.4Å; S285-K289 PolarHBondContact O-N 2.95Å; Y286-K289 PolarHBondContact O-N 3.22Å; K289-K291 VanDerWaalsContact C-N 3.32Å; K289-K291 PolarHBondContact O-N 3.41Å; K289-E292 PolarHBondContact O-N 3.45Å; K289-M293 HydrophobicContact CD-CG 4.46Å; K289-M293 HydrophobicContact CG-SD 4.34Å; K289-M293 WeakPolarHBondContact O-CG 3.33Å; K289-M293 PolarHBondContact O-N 2.87Å; K289-L320 HydrophobicContact CG-CD1 3.72Å; K289-L320 HydrophobicContact CG-CD2 4.35Å
290	I	91.3	Very high	89.9	Confident	6 Å²	6	32.2 Å²	32.2	3%	0.031	18%	0.176	C	C	.	.	H	α-helix	trans	-60.7	-45.3	177.2	-75.3	160.6	0	0	0	110.3	Y286 C287 E292 M293 D294 Y317 L320 L321 R324	Y286-I290 WeakPolarHBondContact O-CB 3.19Å; Y286-I290 WeakPolarHBondContact O-CG1 3.48Å; Y286-I290 PolarHBondContact O-N 2.89Å; C287-I290 PolarHBondContact O-N 3.25Å; I290-E292 PolarHBondContact O-N 2.91Å; I290-M293 WeakPolarHBondContact O-CB 3.21Å; I290-M293 PolarHBondContact O-N 3.12Å; I290-M293 VanDerWaalsContact O-N 3.12Å; I290-D294 VanDerWaalsContact O-CG 3.3Å; I290-D294 PolarHBondContact O-N 2.75Å; I290-Y317 HydrophobicContact CG2-CE2 3.86Å; I290-L320 HydrophobicContact CD1-CB 4.28Å; I290-L320 HydrophobicContact CG1-CB 4Å; I290-L321 HydrophobicContact CD1-CD2 4.08Å; I290-L321 HydrophobicContact CG2-CD2 4.46Å; I290-R324 HydrophobicContact CD1-CB 3.75Å; I290-R324 HydrophobicContact CD1-CG 4.14Å
291	K	89.6	Confident	90	Very high	46 Å²	46	34.7 Å²	34.7	20%	0.2	20%	0.198	C	C	.	.	H	α-helix	trans	-61	-44.5	177.8	-177.9	170	176.6	172.5	0	112.8	Y19 C287 L288 K289 M293 D294 D295	Y19-K291 HydrophobicContact CE1-CD 4.23Å; Y19-K291 HydrophobicContact CE2-CD 4.15Å; C287-K291 WeakPolarHBondContact O-CB 3.43Å; C287-K291 PolarHBondContact O-N 3.42Å; L288-K291 PolarHBondContact O-N 2.9Å; K289-K291 VanDerWaalsContact C-N 3.32Å; K289-K291 PolarHBondContact O-N 3.41Å; K291-M293 VanDerWaalsContact C-N 3.26Å; K291-M293 PolarHBondContact O-N 2.76Å; K291-D294 WeakPolarHBondContact O-CB 3.43Å; K291-D294 PolarHBondContact O-N 2.86Å; K291-D294 VanDerWaalsContact O-N 3.16Å; K291-D295 WeakPolarHBondContact O-CB 3.3Å; K291-D295 VanDerWaalsContact O-CG 3.3Å; K291-D295 PolarHBondContact O-N 3.38Å
292	E	90	Very high	90.1	Very high	38 Å²	38	38.3 Å²	38.3	18%	0.178	23%	0.23	C	C	.	.	H	α-helix	trans	-59.3	-38.7	174.7	-75.5	168.9	-164.1	0	0	112.3	I26 K142 L288 K289 I290 D295 E296	I26-E292 WeakPolarHBondContact CG2-OE1 2.9Å; K142-E292 IonicContact NZ-OE1 2.69Å; K142-E292 PolarHBondContact NZ-OE1 3.3Å; K142-E292 IonicContact NZ-OE2 3.94Å; K142-E292 PolarHBondContact NZ-OE2 2.88Å; L288-E292 WeakPolarHBondContact O-CG 3.38Å; L288-E292 PolarHBondContact O-N 3.4Å; K289-E292 PolarHBondContact O-N 3.45Å; I290-E292 PolarHBondContact O-N 2.91Å; E292-D295 PolarHBondContact O-N 2.81Å; E292-E296 WeakPolarHBondContact O-CB 3.25Å; E292-E296 PolarHBondContact O-N 2.75Å
293	M	91.7	Very high	90.2	Very high	7 Å²	7	43.3 Å²	43.3	3%	0.034	26%	0.255	C	S	.	.	H	α-helix	trans	-69.4	-35.1	176	-67.9	177.9	77	0	0	112.8	K289 I290 K291 E297 R309 E316 Y317 L320	K289-M293 HydrophobicContact CD-CG 4.46Å; K289-M293 HydrophobicContact CG-SD 4.34Å; K289-M293 WeakPolarHBondContact O-CG 3.33Å; K289-M293 PolarHBondContact O-N 2.87Å; I290-M293 WeakPolarHBondContact O-CB 3.21Å; I290-M293 PolarHBondContact O-N 3.12Å; I290-M293 VanDerWaalsContact O-N 3.12Å; K291-M293 VanDerWaalsContact C-N 3.26Å; K291-M293 PolarHBondContact O-N 2.76Å; M293-E297 WeakPolarHBondContact O-CB 3.45Å; M293-E297 PolarHBondContact O-N 3.28Å; M293-R309 PolarHBondContact O-NH2 3.13Å; M293-E316 HydrophobicContact CE-CB 4.47Å; M293-E316 HydrophobicContact CE-CG 4.39Å; M293-Y317 HydrophobicContact CB-CD2 3.95Å; M293-Y317 HydrophobicContact CB-CE2 4.24Å; M293-Y317 HydrophobicContact CE-CD2 3.99Å; M293-Y317 HydrophobicContact CE-CG 4.39Å; M293-Y317 HydrophobicContact SD-CD2 4.07Å; M293-L320 HydrophobicContact CE-CD1 4.37Å; M293-L320 HydrophobicContact SD-CD1 3.31Å; M293-L320 WeakPolarHBondContact SD-CD1 3.36Å
294	D	91.6	Very high	90.1	Very high	61 Å²	61	50.6 Å²	50.6	33%	0.326	29%	0.29	S	S	.	.	H	α-helix	trans	-66.9	-43.8	174	-68.1	-30.4	0	0	0	110.7	I290 K291 E297 A298 Y317	I290-D294 VanDerWaalsContact O-CG 3.3Å; I290-D294 PolarHBondContact O-N 2.75Å; K291-D294 WeakPolarHBondContact O-CB 3.43Å; K291-D294 PolarHBondContact O-N 2.86Å; K291-D294 VanDerWaalsContact O-N 3.16Å; D294-E297 PolarHBondContact O-N 2.82Å; D294-A298 WeakPolarHBondContact O-CB 3.17Å; D294-A298 PolarHBondContact O-N 3.03Å; D294-Y317 WeakPolarHBondContact OD1-CE2 3.43Å; D294-Y317 PolarHBondContact OD1-OH 2.91Å
295	D	91.4	Very high	90.3	Very high	75 Å²	75	56 Å²	56	40%	0.401	32%	0.315	S	S	.	.	H	α-helix	trans	-65.5	-42.1	178.4	-70.4	-22.6	0	0	0	111.3	K291 E292 A298 A299	K291-D295 WeakPolarHBondContact O-CB 3.3Å; K291-D295 VanDerWaalsContact O-CG 3.3Å; K291-D295 PolarHBondContact O-N 3.38Å; E292-D295 PolarHBondContact O-N 2.81Å; D295-A298 PolarHBondContact O-N 2.69Å; D295-A299 WeakPolarHBondContact O-CB 3.37Å; D295-A299 PolarHBondContact O-N 3.41Å
296	E	91.6	Very high	90.3	Very high	85 Å²	85	59.4 Å²	59.4	40%	0.397	33%	0.333	S	S	.	.	H	α-helix	trans	-63.3	-43.1	173.9	-172.5	-165.2	172.6	0	0	111.5	E292 A298 A299 V300 L307 R309	E292-E296 WeakPolarHBondContact O-CB 3.25Å; E292-E296 PolarHBondContact O-N 2.75Å; E296-A298 VanDerWaalsContact C-N 3.34Å; E296-A298 PolarHBondContact O-N 2.64Å; E296-A299 PolarHBondContact O-N 2.66Å; E296-V300 WeakPolarHBondContact O-CG2 3.46Å; E296-V300 PolarHBondContact O-N 3.27Å; E296-L307 HydrophobicContact CG-CD1 4.29Å; E296-L307 HydrophobicContact CG-CD2 4.49Å; E296-R309 IonicContact OE1-NH1 2.71Å; E296-R309 PolarHBondContact OE1-NH1 2.83Å; E296-R309 IonicContact OE2-CZ 3.76Å; E296-R309 IonicContact OE2-NH1 3.61Å; E296-R309 PolarHBondContact OE2-NH1 2.91Å; E296-R309 IonicContact OE2-NH2 3.61Å; E296-R309 PolarHBondContact OE2-NH2 2.82Å
297	E	90.4	Very high	90.3	Very high	52 Å²	52	60.5 Å²	60.5	24%	0.243	34%	0.339	C	S	.	.	H	α-helix	trans	-61.6	-42.8	175.1	-177	175.3	161.6	0	0	111.3	M293 D294 A301 L307	M293-E297 WeakPolarHBondContact O-CB 3.45Å; M293-E297 PolarHBondContact O-N 3.28Å; D294-E297 PolarHBondContact O-N 2.82Å; E297-A301 WeakPolarHBondContact O-CB 3.44Å; E297-A301 PolarHBondContact O-N 2.8Å; E297-L307 HydrophobicContact CB-CD1 4.1Å
298	A	91	Very high	90.4	Very high	61 Å²	61	67.8 Å²	67.8	50%	0.504	36%	0.364	S	S	.	.	H	α-helix	trans	-64	-41.4	176.5	0	0	0	0	0	112.6	D294 D295 E296 A301 A302	D294-A298 WeakPolarHBondContact O-CB 3.17Å; D294-A298 PolarHBondContact O-N 3.03Å; D295-A298 PolarHBondContact O-N 2.69Å; E296-A298 VanDerWaalsContact C-N 3.34Å; E296-A298 PolarHBondContact O-N 2.64Å; A298-A301 PolarHBondContact O-N 2.96Å; A298-A302 WeakPolarHBondContact O-CB 2.95Å; A298-A302 PolarHBondContact O-N 2.96Å
299	A	93.1	Very high	90.6	Very high	55 Å²	55	69.1 Å²	69.1	46%	0.455	37%	0.368	S	S	.	.	H	α-helix	trans	-65.1	-44.5	178.5	0	0	0	0	0	112.2	D295 E296 A302 M303	D295-A299 WeakPolarHBondContact O-CB 3.37Å; D295-A299 PolarHBondContact O-N 3.41Å; E296-A299 PolarHBondContact O-N 2.66Å; A299-A302 WeakPolarHBondContact O-CB 3.26Å; A299-A302 PolarHBondContact O-N 3.44Å; A299-M303 PolarHBondContact O-N 3.44Å
300	V	90.7	Very high	90.8	Very high	21 Å²	21	67.2 Å²	67.2	13%	0.127	36%	0.36	C	S	.	.	H	α-helix	trans	-70.3	-38.3	177.7	179.6	0	0	0	0	111.3	E296 A302 M303 Q304 E305 L307	E296-V300 WeakPolarHBondContact O-CG2 3.46Å; E296-V300 PolarHBondContact O-N 3.27Å; V300-A302 VanDerWaalsContact C-N 3.28Å; V300-A302 PolarHBondContact O-N 2.97Å; V300-M303 HydrophobicContact CB-CE 4.44Å; V300-M303 HydrophobicContact CG2-CE 4.12Å; V300-M303 CarbonylContact O-C 3.58Å; V300-M303 WeakPolarHBondContact O-CA 3.49Å; V300-M303 WeakPolarHBondContact O-CB 3.49Å; V300-M303 PolarHBondContact O-N 2.86Å; V300-Q304 PolarHBondContact O-N 2.85Å; V300-E305 HydrophobicContact CG1-CB 3.56Å; V300-E305 PolarHBondContact O-N 2.87Å; V300-L307 HydrophobicContact CB-CD1 4.31Å; V300-L307 HydrophobicContact CB-CD2 4.5Å; V300-L307 HydrophobicContact CB-CG 4.04Å; V300-L307 HydrophobicContact CG1-CG 4.04Å; V300-L307 HydrophobicContact CG2-CD1 4.29Å; V300-L307 HydrophobicContact CG2-CD2 3.92Å; V300-L307 HydrophobicContact CG2-CG 3.98Å
301	A	88.3	Confident	90.7	Very high	59 Å²	59	71.8 Å²	71.8	49%	0.488	38%	0.381	S	S	.	.	H	α-helix	trans	-61.9	-34.5	173.7	0	0	0	0	0	112.6	E297 A298 M303 Q304	E297-A301 WeakPolarHBondContact O-CB 3.44Å; E297-A301 PolarHBondContact O-N 2.8Å; A298-A301 PolarHBondContact O-N 2.96Å; A301-M303 PolarHBondContact O-N 2.85Å; A301-Q304 PolarHBondContact O-N 3.4Å
302	A	91	Very high	90.7	Very high	87 Å²	87	73.3 Å²	73.3	72%	0.719	39%	0.394	S	S	*	.	H	α-helix	trans	-65	-26.3	174.1	0	0	0	0	0	112.8	A298 A299 V300 Q304	A298-A302 WeakPolarHBondContact O-CB 2.95Å; A298-A302 PolarHBondContact O-N 2.96Å; A299-A302 WeakPolarHBondContact O-CB 3.26Å; A299-A302 PolarHBondContact O-N 3.44Å; V300-A302 VanDerWaalsContact C-N 3.28Å; V300-A302 PolarHBondContact O-N 2.97Å; A302-Q304 VanDerWaalsContact C-N 3.26Å
303	M	91.9	Very high	90.6	Very high	120 Å²	120	71.8 Å²	71.8	59%	0.591	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.9	5.1	172.4	-62.7	-175.3	-72	0	0	113.2	A299 V300 A301 E305	A299-M303 PolarHBondContact O-N 3.44Å; V300-M303 HydrophobicContact CB-CE 4.44Å; V300-M303 HydrophobicContact CG2-CE 4.12Å; V300-M303 CarbonylContact O-C 3.58Å; V300-M303 WeakPolarHBondContact O-CA 3.49Å; V300-M303 WeakPolarHBondContact O-CB 3.49Å; V300-M303 PolarHBondContact O-N 2.86Å; A301-M303 PolarHBondContact O-N 2.85Å; M303-E305 PolarHBondContact O-N 3.06Å
304	Q	87.7	Confident	90.6	Very high	188 Å²	188	71.5 Å²	71.5	88%	0.879	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.6	23.6	-175	-54.9	-175.7	-29.3	0	0	114	V300 A301 A302	V300-Q304 PolarHBondContact O-N 2.85Å; A301-Q304 PolarHBondContact O-N 3.4Å; A302-Q304 VanDerWaalsContact C-N 3.26Å
305	E	91.1	Very high	90.5	Very high	127 Å²	127	70.2 Å²	70.2	59%	0.593	38%	0.379	S	S	*	.			trans	-102.5	166.5	174.4	-70.8	-173.2	-179	0	0	110.7	V300 M303	V300-E305 HydrophobicContact CG1-CB 3.56Å; V300-E305 PolarHBondContact O-N 2.87Å; M303-E305 PolarHBondContact O-N 3.06Å
306	I	88.7	Confident	90.4	Very high	73 Å²	73	69.4 Å²	69.4	37%	0.374	37%	0.372	S	S	.	.			trans	-124.8	130.4	176.6	-50.9	167.1	0	0	0	108.3	V310 E311	I306-V310 HydrophobicContact CG2-CB 4.28Å; I306-V310 HydrophobicContact CG2-CG1 4.42Å; I306-E311 HydrophobicContact CB-CG 3.96Å; I306-E311 HydrophobicContact CG2-CG 3.43Å; I306-E311 VanDerWaalsContact CG2-CG 3.43Å
307	L	91.4	Very high	90.4	Very high	29 Å²	29	66 Å²	66	15%	0.152	36%	0.356	C	S	.	.			trans	-67.2	133.8	174.5	-74.7	156.8	0	0	0	110.6	E296 E297 V300 R309 V310 E311	E296-L307 HydrophobicContact CG-CD1 4.29Å; E296-L307 HydrophobicContact CG-CD2 4.49Å; E297-L307 HydrophobicContact CB-CD1 4.1Å; V300-L307 HydrophobicContact CB-CD1 4.31Å; V300-L307 HydrophobicContact CB-CD2 4.5Å; V300-L307 HydrophobicContact CB-CG 4.04Å; V300-L307 HydrophobicContact CG1-CG 4.04Å; V300-L307 HydrophobicContact CG2-CD1 4.29Å; V300-L307 HydrophobicContact CG2-CD2 3.92Å; V300-L307 HydrophobicContact CG2-CG 3.98Å; L307-R309 HydrophobicContact CB-CG 4.22Å; L307-R309 PolarHBondContact O-N 3.01Å; L307-R309 VanDerWaalsContact O-N 3.14Å; L307-V310 HydrophobicContact CB-CB 4.4Å; L307-V310 HydrophobicContact CB-CG2 3.91Å; L307-V310 HydrophobicContact CD1-CG2 4.47Å; L307-V310 WeakPolarHBondContact O-CA 3.37Å; L307-V310 WeakPolarHBondContact O-CB 3.13Å; L307-V310 PolarHBondContact O-N 3.33Å; L307-E311 PolarHBondContact O-N 2.97Å; L307-E311 VanDerWaalsContact O-N 3.1Å
308	Y	90.6	Very high	90.6	Very high	177 Å²	177	63.9 Å²	63.9	69%	0.694	35%	0.346	S	S	*	.	H	α-helix	trans	-53.2	-38	178.2	177	-100	0	0	0	113.5	V310 E311 T312	Y308-V310 PolarHBondContact O-N 3.13Å; Y308-E311 PolarHBondContact O-N 3.26Å; Y308-T312 HydrophobicContact CD1-CG2 4.43Å; Y308-T312 HydrophobicContact CD2-CG2 4.31Å; Y308-T312 HydrophobicContact CE1-CG2 3.95Å; Y308-T312 HydrophobicContact CE2-CG2 3.83Å; Y308-T312 WeakPolarHBondContact O-CG2 3.14Å; Y308-T312 PolarHBondContact O-N 3.35Å; Y308-T312 VanDerWaalsContact O-N 3.1Å; Y308-T312 PolarHBondContact O-OG1 3.09Å
309	R	92	Very high	90.6	Very high	43 Å²	43	61.3 Å²	61.3	16%	0.162	32%	0.324	C	S	.	.	H	α-helix	trans	-60.1	-35	175.2	71.5	168.3	179.4	-95.1	9.5	112.1	M293 E296 L307 T312 N314	M293-R309 PolarHBondContact O-NH2 3.13Å; E296-R309 IonicContact OE1-NH1 2.71Å; E296-R309 PolarHBondContact OE1-NH1 2.83Å; E296-R309 IonicContact OE2-CZ 3.76Å; E296-R309 IonicContact OE2-NH1 3.61Å; E296-R309 PolarHBondContact OE2-NH1 2.91Å; E296-R309 IonicContact OE2-NH2 3.61Å; E296-R309 PolarHBondContact OE2-NH2 2.82Å; L307-R309 HydrophobicContact CB-CG 4.22Å; L307-R309 PolarHBondContact O-N 3.01Å; L307-R309 VanDerWaalsContact O-N 3.14Å; R309-T312 PolarHBondContact O-OG1 3.35Å; R309-T312 VanDerWaalsContact O-OG1 3.09Å; R309-N314 WeakPolarHBondContact O-CA 3.3Å; R309-N314 PolarHBondContact O-N 3.19Å
310	V	91.9	Very high	90.6	Very high	2 Å²	2	59 Å²	59	1%	0.012	30%	0.303	C	S	.	.	H	α-helix	trans	-77	-42.6	-178.1	-177.9	0	0	0	0	109.9	C67 I306 L307 Y308 T312 G313	C67-V310 HydrophobicContact CB-CG1 3.8Å; C67-V310 PolarHBondContact SG-O 2.93Å; I306-V310 HydrophobicContact CG2-CB 4.28Å; I306-V310 HydrophobicContact CG2-CG1 4.42Å; L307-V310 HydrophobicContact CB-CB 4.4Å; L307-V310 HydrophobicContact CB-CG2 3.91Å; L307-V310 HydrophobicContact CD1-CG2 4.47Å; L307-V310 WeakPolarHBondContact O-CA 3.37Å; L307-V310 WeakPolarHBondContact O-CB 3.13Å; L307-V310 PolarHBondContact O-N 3.33Å; Y308-V310 PolarHBondContact O-N 3.13Å; V310-T312 PolarHBondContact O-N 3.21Å; V310-G313 PolarHBondContact O-N 2.93Å
311	E	89.2	Confident	90.7	Very high	101 Å²	101	58 Å²	58	47%	0.472	30%	0.297	S	S	.	.	H	α-helix	trans	-59.1	-31.6	175	-63.5	-171.4	147.1	0	0	112.6	P68 I306 L307 Y308 G313	P68-E311 WeakPolarHBondContact CD-O 3.41Å; P68-E311 VanDerWaalsContact CG-O 3.27Å; P68-E311 WeakPolarHBondContact CG-O 3.33Å; I306-E311 HydrophobicContact CB-CG 3.96Å; I306-E311 HydrophobicContact CG2-CG 3.43Å; I306-E311 VanDerWaalsContact CG2-CG 3.43Å; L307-E311 PolarHBondContact O-N 2.97Å; L307-E311 VanDerWaalsContact O-N 3.1Å; Y308-E311 PolarHBondContact O-N 3.26Å; E311-G313 VanDerWaalsContact C-N 3.33Å
312	T	88.7	Confident	90.9	Very high	78 Å²	78	55.4 Å²	55.4	48%	0.479	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.8	8.7	179.6	53.2	0	0	0	0	114	Y308 R309 V310	Y308-T312 HydrophobicContact CD1-CG2 4.43Å; Y308-T312 HydrophobicContact CD2-CG2 4.31Å; Y308-T312 HydrophobicContact CE1-CG2 3.95Å; Y308-T312 HydrophobicContact CE2-CG2 3.83Å; Y308-T312 WeakPolarHBondContact O-CG2 3.14Å; Y308-T312 PolarHBondContact O-N 3.35Å; Y308-T312 VanDerWaalsContact O-N 3.1Å; Y308-T312 PolarHBondContact O-OG1 3.09Å; R309-T312 PolarHBondContact O-OG1 3.35Å; R309-T312 VanDerWaalsContact O-OG1 3.09Å; V310-T312 PolarHBondContact O-N 3.21Å
313	G	88.6	Confident	91	Very high	7 Å²	7	51.5 Å²	51.5	7%	0.072	24%	0.242	C	C	.	.	T	Hydrogen-bonded Turn	trans	100.9	12.6	175	0	0	0	0	0	115.6	C69 V310 E311 Y315 R318	C69-G313 VanDerWaalsContact SG-CA 3.53Å; C69-G313 PolarHBondContact SG-O 3.32Å; C69-G313 VanDerWaalsContact SG-O 3.4Å; V310-G313 PolarHBondContact O-N 2.93Å; E311-G313 VanDerWaalsContact C-N 3.33Å; G313-Y315 VanDerWaalsContact C-N 3.34Å; G313-Y315 PolarHBondContact O-N 3.39Å; G313-R318 WeakPolarHBondContact O-CD 3.02Å
314	N	92.4	Very high	91	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	22%	0.222	C	C	.	.			trans	51	45.8	175.7	-149.1	8.1	0	0	0	114.3	Y71 R309 E316 Y317 R318	Y71-N314 HydrophobicContact CE1-CB 4.2Å; Y71-N314 PolarHBondContact OH-ND2 2.91Å; Y71-N314 VanDerWaalsContact OH-ND2 3.09Å; R309-N314 WeakPolarHBondContact O-CA 3.3Å; R309-N314 PolarHBondContact O-N 3.19Å; N314-E316 PolarHBondContact O-N 3.06Å; N314-Y317 WeakPolarHBondContact ND2-CB 3.39Å; N314-Y317 PolarHBondContact O-N 3.2Å; N314-Y317 WeakPolarHBondContact OD1-CB 3.44Å; N314-R318 VanDerWaalsContact O-CG 3.32Å; N314-R318 WeakPolarHBondContact O-CG 3.32Å; N314-R318 PolarHBondContact O-N 3.21Å
315	Y	88.5	Confident	91.2	Very high	35 Å²	35	40.4 Å²	40.4	14%	0.137	19%	0.187	C	C	.	.	H	α-helix	trans	-55.7	-53.4	-172.8	174.8	-87.8	0	0	0	113.2	F36 M39 L127 G313 Y317 R318 L319	F36-Y315 AromaticContact CD1-CD1 3.77Å; F36-Y315 HydrophobicContact CD1-CD1 3.77Å; F36-Y315 AromaticContact CD1-CE1 3.68Å; F36-Y315 HydrophobicContact CD1-CE1 3.68Å; F36-Y315 HydrophobicContact CD1-CE2 4.48Å; F36-Y315 HydrophobicContact CD1-CG 4.32Å; F36-Y315 AromaticContact CD2-CD1 3.99Å; F36-Y315 HydrophobicContact CD2-CD1 3.99Å; F36-Y315 AromaticContact CD2-CE1 3.56Å; F36-Y315 HydrophobicContact CD2-CE1 3.56Å; F36-Y315 AromaticContact CE1-CD1 3.73Å; F36-Y315 HydrophobicContact CE1-CD1 3.73Å; F36-Y315 HydrophobicContact CE1-CD2 4.19Å; F36-Y315 AromaticContact CE1-CE1 3.2Å; F36-Y315 HydrophobicContact CE1-CE1 3.2Å; F36-Y315 AromaticContact CE1-CE2 3.66Å; F36-Y315 HydrophobicContact CE1-CE2 3.66Å; F36-Y315 HydrophobicContact CE1-CG 4.24Å; F36-Y315 AromaticContact CE1-CZ 3.16Å; F36-Y315 WeakPolarHBondContact CE1-OH 3.17Å; F36-Y315 AromaticContact CE2-CD1 3.99Å; F36-Y315 HydrophobicContact CE2-CD1 3.99Å; F36-Y315 AromaticContact CE2-CE1 3.1Å; F36-Y315 HydrophobicContact CE2-CE1 3.1Å; F36-Y315 AromaticContact CE2-CZ 3.62Å; F36-Y315 AromaticContact CG-CD1 3.96Å; F36-Y315 HydrophobicContact CG-CD1 3.96Å; F36-Y315 AromaticContact CG-CE1 3.88Å; F36-Y315 HydrophobicContact CG-CE1 3.88Å; F36-Y315 AromaticContact CZ-CD1 3.93Å; F36-Y315 HydrophobicContact CZ-CD1 3.93Å; F36-Y315 AromaticContact CZ-CE1 2.97Å; F36-Y315 HydrophobicContact CZ-CE1 2.97Å; F36-Y315 AromaticContact CZ-CE2 3.92Å; F36-Y315 HydrophobicContact CZ-CE2 3.92Å; F36-Y315 AromaticContact CZ-CZ 2.97Å; F36-Y315 WeakPolarHBondContact CZ-OH 3.47Å; M39-Y315 HydrophobicContact CB-CD2 3.94Å; M39-Y315 HydrophobicContact CB-CE2 3.5Å; M39-Y315 VanDerWaalsContact CB-CE2 3.5Å; M39-Y315 HydrophobicContact CE-CD2 3.26Å; M39-Y315 HydrophobicContact CE-CE2 3.27Å; M39-Y315 HydrophobicContact CE-CG 4.48Å; M39-Y315 HydrophobicContact CG-CD2 3.93Å; M39-Y315 HydrophobicContact CG-CE2 3.4Å; M39-Y315 VanDerWaalsContact CG-CE2 3.4Å; M39-Y315 HydrophobicContact SD-CD2 3.37Å; M39-Y315 WeakPolarHBondContact SD-CD2 3.38Å; M39-Y315 HydrophobicContact SD-CE2 3.46Å; M39-Y315 WeakPolarHBondContact SD-CE2 3.43Å; L127-Y315 HydrophobicContact CD1-CE2 4.31Å; G313-Y315 VanDerWaalsContact C-N 3.34Å; G313-Y315 PolarHBondContact O-N 3.39Å; Y315-Y317 VanDerWaalsContact C-N 3.26Å; Y315-Y317 PolarHBondContact O-N 2.93Å; Y315-R318 WeakPolarHBondContact O-CB 3.4Å; Y315-R318 PolarHBondContact O-N 3.41Å; Y315-R318 VanDerWaalsContact O-N 3.1Å; Y315-L319 HydrophobicContact CE1-CB 4Å; Y315-L319 HydrophobicContact CE1-CD2 3.91Å; Y315-L319 PolarHBondContact O-N 3.25Å
316	E	89.3	Confident	91.3	Very high	58 Å²	58	38 Å²	38	27%	0.271	18%	0.176	S	C	.	.	H	α-helix	trans	-60.7	-40.7	-175.1	-177.3	174.8	-177.1	0	0	111	M293 N314 L319 L320	M293-E316 HydrophobicContact CE-CB 4.47Å; M293-E316 HydrophobicContact CE-CG 4.39Å; N314-E316 PolarHBondContact O-N 3.06Å; E316-L319 PolarHBondContact O-N 3Å; E316-L320 HydrophobicContact CG-CD1 4.24Å; E316-L320 VanDerWaalsContact O-CG 3.32Å; E316-L320 WeakPolarHBondContact O-CG 3.36Å; E316-L320 PolarHBondContact O-N 3.45Å
317	Y	92.8	Very high	91.4	Very high	13 Å²	13	34.8 Å²	34.8	5%	0.051	16%	0.16	C	C	.	.	H	α-helix	trans	-62.5	-45.5	175.1	-173.1	-97.2	0	0	0	111.8	Y71 I290 M293 D294 N314 Y315 L319 L320 L321	Y71-Y317 AromaticContact CE2-CD1 3.98Å; Y71-Y317 HydrophobicContact CE2-CD1 3.98Å; Y71-Y317 HydrophobicContact CE2-CE1 4.08Å; I290-Y317 HydrophobicContact CG2-CE2 3.86Å; M293-Y317 HydrophobicContact CB-CD2 3.95Å; M293-Y317 HydrophobicContact CB-CE2 4.24Å; M293-Y317 HydrophobicContact CE-CD2 3.99Å; M293-Y317 HydrophobicContact CE-CG 4.39Å; M293-Y317 HydrophobicContact SD-CD2 4.07Å; D294-Y317 WeakPolarHBondContact OD1-CE2 3.43Å; D294-Y317 PolarHBondContact OD1-OH 2.91Å; N314-Y317 WeakPolarHBondContact ND2-CB 3.39Å; N314-Y317 PolarHBondContact O-N 3.2Å; N314-Y317 WeakPolarHBondContact OD1-CB 3.44Å; Y315-Y317 VanDerWaalsContact C-N 3.26Å; Y315-Y317 PolarHBondContact O-N 2.93Å; Y317-L319 VanDerWaalsContact C-N 3.33Å; Y317-L319 PolarHBondContact O-N 3.46Å; Y317-L320 PolarHBondContact O-N 2.93Å; Y317-L320 VanDerWaalsContact O-N 3.15Å; Y317-L321 HydrophobicContact CD1-CD1 3.66Å; Y317-L321 HydrophobicContact CD1-CG 3.98Å; Y317-L321 HydrophobicContact CE1-CD1 3.44Å; Y317-L321 VanDerWaalsContact CE1-CD1 3.44Å; Y317-L321 HydrophobicContact CE1-CD2 4.01Å; Y317-L321 HydrophobicContact CE1-CG 3.78Å; Y317-L321 WeakPolarHBondContact O-CG 3.29Å; Y317-L321 PolarHBondContact O-N 3.19Å
318	R	93.1	Very high	91.4	Very high	8 Å²	8	35.8 Å²	35.8	3%	0.03	16%	0.163	C	C	.	.	H	α-helix	trans	-62.2	-39.4	177.1	-68.6	169.6	61.1	-172.4	-2.9	112.4	Y71 G90 E92 L127 G313 N314 Y315 L321 R322	Y71-R318 HydrophobicContact CD1-CG 4.16Å; Y71-R318 HydrophobicContact CD2-CG 3.81Å; Y71-R318 HydrophobicContact CE1-CG 4.43Å; Y71-R318 HydrophobicContact CE2-CG 4.1Å; Y71-R318 HydrophobicContact CG-CG 3.85Å; G90-R318 VanDerWaalsContact O-CZ 3.31Å; G90-R318 PolarHBondContact O-NE 3.35Å; G90-R318 PolarHBondContact O-NH2 3.19Å; E92-R318 VanDerWaalsContact CB-NH2 3.32Å; L127-R318 HydrophobicContact CD2-CB 4.01Å; G313-R318 WeakPolarHBondContact O-CD 3.02Å; N314-R318 VanDerWaalsContact O-CG 3.32Å; N314-R318 WeakPolarHBondContact O-CG 3.32Å; N314-R318 PolarHBondContact O-N 3.21Å; Y315-R318 WeakPolarHBondContact O-CB 3.4Å; Y315-R318 PolarHBondContact O-N 3.41Å; Y315-R318 VanDerWaalsContact O-N 3.1Å; R318-L321 PolarHBondContact O-N 2.83Å; R318-R322 PolarHBondContact O-N 2.95Å; R318-R322 VanDerWaalsContact O-N 3.12Å
319	L	91.6	Very high	91.4	Very high	7 Å²	7	32.8 Å²	32.8	4%	0.037	15%	0.154	C	C	.	.	H	α-helix	trans	-62.5	-43.4	173.2	176.2	62.5	0	0	0	111.3	F36 A129 Q133 Y315 E316 Y317 R322 C323	F36-L319 HydrophobicContact CE2-CD2 4.31Å; A129-L319 HydrophobicContact CB-CD1 3.36Å; Q133-L319 HydrophobicContact CB-CD2 3.79Å; Y315-L319 HydrophobicContact CE1-CB 4Å; Y315-L319 HydrophobicContact CE1-CD2 3.91Å; Y315-L319 PolarHBondContact O-N 3.25Å; E316-L319 PolarHBondContact O-N 3Å; Y317-L319 VanDerWaalsContact C-N 3.33Å; Y317-L319 PolarHBondContact O-N 3.46Å; L319-R322 WeakPolarHBondContact O-CB 3.25Å; L319-R322 PolarHBondContact O-N 3.31Å; L319-C323 PolarHBondContact O-N 3.28Å; L319-C323 PolarHBondContact O-SG 3.12Å
320	L	92.4	Very high	91.4	Very high	5 Å²	5	35.2 Å²	35.2	3%	0.026	17%	0.166	C	C	.	.	H	α-helix	trans	-66.3	-39.3	177.3	-72.8	166.3	0	0	0	112.2	I139 Y286 K289 I290 M293 E316 Y317 R322 C323 R324	I139-L320 HydrophobicContact CD1-CD2 4.16Å; I139-L320 HydrophobicContact CG1-CD2 4.42Å; Y286-L320 HydrophobicContact CD1-CD2 3.77Å; Y286-L320 HydrophobicContact CE1-CD2 3.99Å; K289-L320 HydrophobicContact CG-CD1 3.72Å; K289-L320 HydrophobicContact CG-CD2 4.35Å; I290-L320 HydrophobicContact CD1-CB 4.28Å; I290-L320 HydrophobicContact CG1-CB 4Å; M293-L320 HydrophobicContact CE-CD1 4.37Å; M293-L320 HydrophobicContact SD-CD1 3.31Å; M293-L320 WeakPolarHBondContact SD-CD1 3.36Å; E316-L320 HydrophobicContact CG-CD1 4.24Å; E316-L320 VanDerWaalsContact O-CG 3.32Å; E316-L320 WeakPolarHBondContact O-CG 3.36Å; E316-L320 PolarHBondContact O-N 3.45Å; Y317-L320 PolarHBondContact O-N 2.93Å; Y317-L320 VanDerWaalsContact O-N 3.15Å; L320-R322 VanDerWaalsContact C-N 3.28Å; L320-R322 PolarHBondContact O-N 3.08Å; L320-C323 PolarHBondContact O-N 3.28Å; L320-R324 VanDerWaalsContact O-CB 3.32Å; L320-R324 WeakPolarHBondContact O-CB 3.48Å; L320-R324 PolarHBondContact O-N 3.39Å
321	L	93.6	Very high	91.3	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-57.8	-42.4	173.2	-72.1	175.2	0	0	0	111.5	Y71 V73 A89 I290 Y317 R318 Q325	Y71-L321 HydrophobicContact CD2-CD1 4.3Å; Y71-L321 HydrophobicContact CE2-CD1 4.17Å; V73-L321 HydrophobicContact CB-CD1 4.46Å; V73-L321 HydrophobicContact CG1-CD2 4.16Å; V73-L321 HydrophobicContact CG2-CD1 4.37Å; A89-L321 HydrophobicContact CB-CB 4.17Å; I290-L321 HydrophobicContact CD1-CD2 4.08Å; I290-L321 HydrophobicContact CG2-CD2 4.46Å; Y317-L321 HydrophobicContact CD1-CD1 3.66Å; Y317-L321 HydrophobicContact CD1-CG 3.98Å; Y317-L321 HydrophobicContact CE1-CD1 3.44Å; Y317-L321 VanDerWaalsContact CE1-CD1 3.44Å; Y317-L321 HydrophobicContact CE1-CD2 4.01Å; Y317-L321 HydrophobicContact CE1-CG 3.78Å; Y317-L321 WeakPolarHBondContact O-CG 3.29Å; Y317-L321 PolarHBondContact O-N 3.19Å; R318-L321 PolarHBondContact O-N 2.83Å; L321-Q325 PolarHBondContact O-N 3.44Å
322	R	92.4	Very high	91.3	Very high	6 Å²	6	32.9 Å²	32.9	2%	0.023	16%	0.162	C	C	.	.	H	α-helix	trans	-62.4	-52.4	174.6	179.2	53.5	52.7	124	11.4	111.8	E88 A89 D91 A129 R318 L319 L320 R324 Q325 E326	E88-R322 PolarHBondContact O-NH2 2.89Å; E88-R322 IonicContact OE1-NH1 2.66Å; E88-R322 IonicContact OE2-CZ 3.98Å; E88-R322 IonicContact OE2-NH1 2.61Å; E88-R322 PolarHBondContact OE2-NH1 3.44Å; A89-R322 PolarHBondContact O-NE 3.27Å; A89-R322 PolarHBondContact O-NH2 3.07Å; D91-R322 VanDerWaalsContact CG-NH2 3.31Å; D91-R322 IonicContact OD1-CZ 3.27Å; D91-R322 IonicContact OD1-NH2 2.64Å; D91-R322 PolarHBondContact OD1-NH2 2.97Å; D91-R322 IonicContact OD2-NH2 2.77Å; A129-R322 HydrophobicContact CB-CB 4.16Å; A129-R322 HydrophobicContact CB-CG 3.54Å; R318-R322 PolarHBondContact O-N 2.95Å; R318-R322 VanDerWaalsContact O-N 3.12Å; L319-R322 WeakPolarHBondContact O-CB 3.25Å; L319-R322 PolarHBondContact O-N 3.31Å; L320-R322 VanDerWaalsContact C-N 3.28Å; L320-R322 PolarHBondContact O-N 3.08Å; R322-R324 VanDerWaalsContact C-N 3.28Å; R322-R324 PolarHBondContact O-N 3.43Å; R322-Q325 WeakPolarHBondContact O-CB 3.08Å; R322-Q325 PolarHBondContact O-N 3.39Å; R322-E326 PolarHBondContact O-N 2.84Å
323	C	92.6	Very high	91.4	Very high	4 Å²	4	36.1 Å²	36.1	3%	0.027	17%	0.17	C	C	.	.	H	α-helix	trans	-60.1	-39.6	179.8	-63.5	0	0	0	0	111.6	Y286 L319 L320 E326 A327	Y286-C323 HydrophobicContact CD1-CB 4.01Å; Y286-C323 HydrophobicContact CD2-CB 4.34Å; Y286-C323 HydrophobicContact CE1-CB 3.57Å; Y286-C323 HydrophobicContact CE2-CB 3.93Å; Y286-C323 HydrophobicContact CG-CB 4.4Å; L319-C323 PolarHBondContact O-N 3.28Å; L319-C323 PolarHBondContact O-SG 3.12Å; L320-C323 PolarHBondContact O-N 3.28Å; C323-E326 PolarHBondContact O-N 2.85Å; C323-A327 VanDerWaalsContact O-CB 3.26Å; C323-A327 WeakPolarHBondContact O-CB 3.2Å; C323-A327 PolarHBondContact O-N 3.44Å
324	R	92.9	Very high	91.6	Very high	45 Å²	45	37.2 Å²	37.2	17%	0.17	17%	0.174	C	C	.	.	H	α-helix	trans	-59.6	-45.9	173.1	-175.3	-171.2	62.3	158.7	1.3	111.4	V73 Y283 I290 L320 R322 A327 K328	V73-R324 PolarHBondContact O-NH2 2.95Å; Y283-R324 HydrophobicContact CD2-CG 4.11Å; Y283-R324 HydrophobicContact CE2-CG 3.73Å; I290-R324 HydrophobicContact CD1-CB 3.75Å; I290-R324 HydrophobicContact CD1-CG 4.14Å; L320-R324 VanDerWaalsContact O-CB 3.32Å; L320-R324 WeakPolarHBondContact O-CB 3.48Å; L320-R324 PolarHBondContact O-N 3.39Å; R322-R324 VanDerWaalsContact C-N 3.28Å; R322-R324 PolarHBondContact O-N 3.43Å; R324-A327 PolarHBondContact O-N 2.86Å; R324-K328 WeakPolarHBondContact O-CB 3.32Å; R324-K328 PolarHBondContact O-N 3Å
325	Q	92.1	Very high	91.4	Very high	31 Å²	31	40.6 Å²	40.6	15%	0.145	19%	0.187	C	C	.	.	H	α-helix	trans	-63.7	-42.9	-179.8	-170.9	-175.3	19.3	0	0	111.6	A89 L321 R322 K328 K329	A89-Q325 HydrophobicContact CB-CB 4.22Å; L321-Q325 PolarHBondContact O-N 3.44Å; R322-Q325 WeakPolarHBondContact O-CB 3.08Å; R322-Q325 PolarHBondContact O-N 3.39Å; Q325-K328 WeakPolarHBondContact O-CB 3.36Å; Q325-K328 PolarHBondContact O-N 2.91Å; Q325-K329 WeakPolarHBondContact O-CG 3.14Å; Q325-K329 PolarHBondContact O-N 3.49Å
326	E	92.3	Very high	91.5	Very high	76 Å²	76	42.2 Å²	42.2	36%	0.355	20%	0.203	S	C	.	.	H	α-helix	trans	-66.1	-44.8	176.5	-70.3	177.3	-172.4	0	0	111.9	R322 C323 K328 K329 K330	R322-E326 PolarHBondContact O-N 2.84Å; C323-E326 PolarHBondContact O-N 2.85Å; E326-K328 PolarHBondContact O-N 2.81Å; E326-K329 PolarHBondContact O-N 3.44Å; E326-K330 WeakPolarHBondContact O-CB 3.4Å; E326-K330 PolarHBondContact O-N 3.25Å
327	A	91.7	Very high	91.5	Very high	6 Å²	6	42.6 Å²	42.6	5%	0.05	21%	0.207	C	C	.	.	H	α-helix	trans	-59.9	-37.1	173.4	0	0	0	0	0	111.2	Y283 Y286 C323 R324 K330 F331	Y283-A327 HydrophobicContact CD2-CB 4.32Å; Y286-A327 HydrophobicContact CD2-CB 3.86Å; Y286-A327 HydrophobicContact CE2-CB 4.12Å; C323-A327 VanDerWaalsContact O-CB 3.26Å; C323-A327 WeakPolarHBondContact O-CB 3.2Å; C323-A327 PolarHBondContact O-N 3.44Å; R324-A327 PolarHBondContact O-N 2.86Å; A327-K330 PolarHBondContact O-N 3.32Å; A327-F331 WeakPolarHBondContact O-CD1 3.28Å; A327-F331 PolarHBondContact O-N 3.41Å
328	K	90.7	Very high	91.4	Very high	50 Å²	50	42.1 Å²	42.1	22%	0.217	21%	0.205	C	C	.	.	H	α-helix	trans	-59.2	-54.7	174.7	-176.8	168.4	177.8	-167.3	0	112.2	E77 Y283 R324 Q325 E326 K330 F331 A332	E77-K328 WeakPolarHBondContact OE1-CE 3.38Å; E77-K328 IonicContact OE1-NZ 3.62Å; E77-K328 PolarHBondContact OE1-NZ 3.23Å; Y283-K328 HydrophobicContact CD2-CB 3.94Å; Y283-K328 HydrophobicContact CE2-CB 3.66Å; Y283-K328 HydrophobicContact CE2-CD 4.36Å; Y283-K328 HydrophobicContact CE2-CG 4.18Å; R324-K328 WeakPolarHBondContact O-CB 3.32Å; R324-K328 PolarHBondContact O-N 3Å; Q325-K328 WeakPolarHBondContact O-CB 3.36Å; Q325-K328 PolarHBondContact O-N 2.91Å; E326-K328 PolarHBondContact O-N 2.81Å; K328-K330 VanDerWaalsContact C-N 3.3Å; K328-K330 PolarHBondContact O-N 3.43Å; K328-F331 HydrophobicContact CB-CD1 4.33Å; K328-F331 HydrophobicContact CB-CE1 3.84Å; K328-F331 HydrophobicContact CG-CD1 4.41Å; K328-F331 HydrophobicContact CG-CE1 3.55Å; K328-F331 HydrophobicContact CG-CZ 3.93Å; K328-F331 VanDerWaalsContact O-CD1 3.25Å; K328-F331 WeakPolarHBondContact O-CD1 3.45Å; K328-F331 WeakPolarHBondContact O-CE1 3.48Å; K328-F331 PolarHBondContact O-N 3.36Å; K328-A332 WeakPolarHBondContact O-CB 3.34Å; K328-A332 PolarHBondContact O-N 3.35Å
329	K	91.4	Very high	91.2	Very high	113 Å²	113	44.7 Å²	44.7	49%	0.491	22%	0.219	S	C	.	.	H	α-helix	trans	-57	-44.4	177.5	-68.8	174.7	-179.4	177.8	0	111.2	E88 Q325 E326 K333	E88-K329 IonicContact OE1-NZ 3.16Å; E88-K329 PolarHBondContact OE1-NZ 3.09Å; E88-K329 VanDerWaalsContact OE1-NZ 3.16Å; Q325-K329 WeakPolarHBondContact O-CG 3.14Å; Q325-K329 PolarHBondContact O-N 3.49Å; E326-K329 PolarHBondContact O-N 3.44Å; K329-K333 PolarHBondContact O-N 2.99Å; K329-K333 VanDerWaalsContact O-N 3.11Å
330	K	91.9	Very high	91.1	Very high	95 Å²	95	48 Å²	48	41%	0.413	24%	0.239	S	C	.	.	H	α-helix	trans	-63.5	-48.3	179.8	-177.4	-174.9	169.3	-167.3	0	112.6	A279 E282 E326 A327 K328 L334	A279-K330 HydrophobicContact CB-CD 4.42Å; A279-K330 HydrophobicContact CB-CG 4.37Å; E282-K330 IonicContact OE2-NZ 3.33Å; E282-K330 PolarHBondContact OE2-NZ 2.96Å; E326-K330 WeakPolarHBondContact O-CB 3.4Å; E326-K330 PolarHBondContact O-N 3.25Å; A327-K330 PolarHBondContact O-N 3.32Å; K328-K330 VanDerWaalsContact C-N 3.3Å; K328-K330 PolarHBondContact O-N 3.43Å; K330-L334 HydrophobicContact CG-CD1 4.25Å; K330-L334 WeakPolarHBondContact O-CG 2.88Å; K330-L334 PolarHBondContact O-N 3.06Å; K330-L334 VanDerWaalsContact O-N 3.14Å
331	F	88.4	Confident	90.9	Very high	8 Å²	8	50.7 Å²	50.7	4%	0.035	25%	0.251	C	S	.	.	H	α-helix	trans	-67.1	-38.9	179.7	88.5	-112.6	0	0	0	111.1	F11 A279 Y283 A327 K328 K333 L334 R335	F11-F331 HydrophobicContact CZ-CE2 4.5Å; A279-F331 HydrophobicContact CB-CB 4.2Å; Y283-F331 AromaticContact CD1-CD1 3.67Å; Y283-F331 HydrophobicContact CD1-CD1 3.67Å; Y283-F331 AromaticContact CD1-CE1 3.38Å; Y283-F331 HydrophobicContact CD1-CE1 3.38Å; Y283-F331 HydrophobicContact CD1-CZ 4.27Å; Y283-F331 AromaticContact CD2-CD1 3.93Å; Y283-F331 HydrophobicContact CD2-CD1 3.93Å; Y283-F331 AromaticContact CD2-CE1 3.75Å; Y283-F331 HydrophobicContact CD2-CE1 3.75Å; Y283-F331 HydrophobicContact CE1-CD1 4.27Å; Y283-F331 AromaticContact CE1-CE1 3.5Å; Y283-F331 HydrophobicContact CE1-CE1 3.5Å; Y283-F331 HydrophobicContact CE1-CZ 4.12Å; Y283-F331 HydrophobicContact CE2-CD1 4.5Å; Y283-F331 AromaticContact CE2-CE1 3.86Å; Y283-F331 HydrophobicContact CE2-CE1 3.86Å; Y283-F331 AromaticContact CG-CD1 3.46Å; Y283-F331 HydrophobicContact CG-CD1 3.46Å; Y283-F331 VanDerWaalsContact CG-CD1 3.46Å; Y283-F331 AromaticContact CG-CE1 3.5Å; Y283-F331 HydrophobicContact CG-CE1 3.5Å; Y283-F331 AromaticContact CZ-CE1 3.74Å; A327-F331 WeakPolarHBondContact O-CD1 3.28Å; A327-F331 PolarHBondContact O-N 3.41Å; K328-F331 HydrophobicContact CB-CD1 4.33Å; K328-F331 HydrophobicContact CB-CE1 3.84Å; K328-F331 HydrophobicContact CG-CD1 4.41Å; K328-F331 HydrophobicContact CG-CE1 3.55Å; K328-F331 HydrophobicContact CG-CZ 3.93Å; K328-F331 VanDerWaalsContact O-CD1 3.25Å; K328-F331 WeakPolarHBondContact O-CD1 3.45Å; K328-F331 WeakPolarHBondContact O-CE1 3.48Å; K328-F331 PolarHBondContact O-N 3.36Å; F331-K333 PolarHBondContact O-N 3.42Å; F331-L334 PolarHBondContact O-N 2.85Å; F331-R335 WeakPolarHBondContact O-CB 3.5Å; F331-R335 PolarHBondContact O-N 3.19Å
332	A	89	Confident	90.6	Very high	46 Å²	46	51.7 Å²	51.7	38%	0.38	26%	0.256	S	S	.	.	H	α-helix	trans	-63.5	-42.9	-178.6	0	0	0	0	0	111.2	K328 R335 S336	K328-A332 WeakPolarHBondContact O-CB 3.34Å; K328-A332 PolarHBondContact O-N 3.35Å; A332-R335 WeakPolarHBondContact O-CB 3.2Å; A332-R335 PolarHBondContact O-N 3.18Å; A332-S336 PolarHBondContact O-N 3.37Å; A332-S336 VanDerWaalsContact O-N 3.17Å
333	K	91.7	Very high	90.3	Very high	146 Å²	146	57.1 Å²	57.1	64%	0.635	28%	0.282	S	S	*	.	H	α-helix	trans	-59.8	-50.2	172.9	-175.2	176.4	179.5	176.6	0	111.9	K329 F331 R335 S336 D337	K329-K333 PolarHBondContact O-N 2.99Å; K329-K333 VanDerWaalsContact O-N 3.11Å; F331-K333 PolarHBondContact O-N 3.42Å; K333-R335 VanDerWaalsContact C-N 3.26Å; K333-R335 PolarHBondContact O-N 3.11Å; K333-S336 WeakPolarHBondContact O-CB 3.48Å; K333-S336 PolarHBondContact O-N 2.8Å; K333-S336 VanDerWaalsContact O-N 3.16Å; K333-D337 PolarHBondContact O-N 2.76Å
334	L	91.9	Very high	90	Very high	29 Å²	29	61.9 Å²	61.9	15%	0.152	31%	0.307	C	S	.	.	H	α-helix	trans	-63.3	-31.7	179.3	-74	169.1	0	0	0	112.8	Y276 A279 K330 F331 D337 V338	Y276-L334 HydrophobicContact CD2-CB 4.23Å; A279-L334 HydrophobicContact CB-CD1 3.57Å; K330-L334 HydrophobicContact CG-CD1 4.25Å; K330-L334 WeakPolarHBondContact O-CG 2.88Å; K330-L334 PolarHBondContact O-N 3.06Å; K330-L334 VanDerWaalsContact O-N 3.14Å; F331-L334 PolarHBondContact O-N 2.85Å; L334-D337 PolarHBondContact O-N 3.25Å; L334-V338 WeakPolarHBondContact O-CB 3.37Å; L334-V338 VanDerWaalsContact O-CG2 3.25Å; L334-V338 WeakPolarHBondContact O-CG2 3.21Å; L334-V338 PolarHBondContact O-N 3.09Å
335	R	89	Confident	89.7	Confident	72 Å²	72	60.4 Å²	60.4	27%	0.272	30%	0.302	S	S	.	.	H	α-helix	trans	-62.5	-46.8	173.8	-177.6	175.4	163.8	163.8	-9.3	111	F11 L172 Y276 F331 A332 K333 V338 L339	F11-R335 VanDerWaalsContact CZ-NH1 3.27Å; L172-R335 HydrophobicContact CD1-CG 4Å; Y276-R335 HydrophobicContact CD2-CB 4.04Å; Y276-R335 HydrophobicContact CE2-CB 3.68Å; Y276-R335 HydrophobicContact CE2-CG 4.17Å; F331-R335 WeakPolarHBondContact O-CB 3.5Å; F331-R335 PolarHBondContact O-N 3.19Å; A332-R335 WeakPolarHBondContact O-CB 3.2Å; A332-R335 PolarHBondContact O-N 3.18Å; K333-R335 VanDerWaalsContact C-N 3.26Å; K333-R335 PolarHBondContact O-N 3.11Å; R335-V338 PolarHBondContact O-N 2.81Å; R335-L339 HydrophobicContact CG-CD1 4.2Å; R335-L339 WeakPolarHBondContact O-CG 3.43Å; R335-L339 PolarHBondContact O-N 3.23Å
336	S	89.8	Confident	89.2	Confident	69 Å²	69	62.7 Å²	62.7	48%	0.483	32%	0.315	S	S	.	.	H	α-helix	trans	-60	-47.8	175.5	-172.5	0	0	0	0	111	A332 K333 V338 L339 V340	A332-S336 PolarHBondContact O-N 3.37Å; A332-S336 VanDerWaalsContact O-N 3.17Å; K333-S336 WeakPolarHBondContact O-CB 3.48Å; K333-S336 PolarHBondContact O-N 2.8Å; K333-S336 VanDerWaalsContact O-N 3.16Å; S336-V338 VanDerWaalsContact C-N 3.32Å; S336-V338 PolarHBondContact O-N 2.9Å; S336-L339 PolarHBondContact O-N 3.18Å; S336-V340 WeakPolarHBondContact O-CG2 3.31Å; S336-V340 PolarHBondContact O-N 3.49Å
337	D	90.5	Very high	88.6	Confident	65 Å²	65	64.2 Å²	64.2	35%	0.348	32%	0.322	S	S	.	.	H	α-helix	trans	-57.8	-43.7	178	-65.8	-19.7	0	0	0	112.1	K333 L334 K341	K333-D337 PolarHBondContact O-N 2.76Å; L334-D337 PolarHBondContact O-N 3.25Å; D337-K341 WeakPolarHBondContact O-CB 3.46Å; D337-K341 WeakPolarHBondContact O-CG 3.3Å; D337-K341 PolarHBondContact O-N 3.24Å
338	V	90.1	Very high	87.8	Confident	3 Å²	3	69 Å²	69	2%	0.018	34%	0.342	C	S	.	.	H	α-helix	trans	-64.1	-45.3	177.3	162.6	0	0	0	0	111.6	L172 T272 L273 Y276 L334 R335 S336 V340 K341 L342	L172-V338 HydrophobicContact CD1-CG1 3.94Å; L172-V338 HydrophobicContact CD2-CG1 3.78Å; L172-V338 HydrophobicContact CG-CG1 4.41Å; T272-V338 HydrophobicContact CG2-CG2 3.92Å; L273-V338 HydrophobicContact CB-CG2 4.39Å; L273-V338 HydrophobicContact CD1-CB 4.42Å; L273-V338 HydrophobicContact CD1-CG1 3.52Å; L273-V338 HydrophobicContact CD1-CG2 4.02Å; Y276-V338 HydrophobicContact CG-CG2 4.25Å; L334-V338 WeakPolarHBondContact O-CB 3.37Å; L334-V338 VanDerWaalsContact O-CG2 3.25Å; L334-V338 WeakPolarHBondContact O-CG2 3.21Å; L334-V338 PolarHBondContact O-N 3.09Å; R335-V338 PolarHBondContact O-N 2.81Å; S336-V338 VanDerWaalsContact C-N 3.32Å; S336-V338 PolarHBondContact O-N 2.9Å; V338-V340 PolarHBondContact O-N 2.8Å; V338-K341 PolarHBondContact O-N 3.17Å; V338-L342 HydrophobicContact CG1-CD1 3.79Å; V338-L342 HydrophobicContact CG1-CG 4.3Å; V338-L342 WeakPolarHBondContact O-CB 3.46Å; V338-L342 WeakPolarHBondContact O-CG 3.4Å; V338-L342 PolarHBondContact O-N 2.83Å
339	L	88.2	Confident	87	Confident	63 Å²	63	69.5 Å²	69.5	33%	0.33	34%	0.342	S	S	.	.	H	α-helix	trans	-61.2	-46.2	-179.1	-76.5	169.3	0	0	0	111	L172 R335 S336 L342 E343	L172-L339 HydrophobicContact CD2-CD2 3.74Å; L172-L339 HydrophobicContact CD2-CG 4.29Å; R335-L339 HydrophobicContact CG-CD1 4.2Å; R335-L339 WeakPolarHBondContact O-CG 3.43Å; R335-L339 PolarHBondContact O-N 3.23Å; S336-L339 PolarHBondContact O-N 3.18Å; L339-L342 PolarHBondContact O-N 3.5Å; L339-E343 WeakPolarHBondContact O-CB 3.32Å; L339-E343 PolarHBondContact O-N 2.68Å
340	V	90.3	Very high	86	Confident	76 Å²	76	68.2 Å²	68.2	46%	0.461	34%	0.344	S	S	.	.	H	α-helix	trans	-61.9	-45.5	176.5	175	0	0	0	0	110.9	S336 V338 L342 E343 L344	S336-V340 WeakPolarHBondContact O-CG2 3.31Å; S336-V340 PolarHBondContact O-N 3.49Å; V338-V340 PolarHBondContact O-N 2.8Å; V340-L342 PolarHBondContact O-N 3.26Å; V340-E343 PolarHBondContact O-N 3.2Å; V340-L344 HydrophobicContact CG1-CD1 4.03Å; V340-L344 HydrophobicContact CG1-CG 4.43Å; V340-L344 VanDerWaalsContact O-CG 3.31Å; V340-L344 WeakPolarHBondContact O-CG 3.32Å; V340-L344 PolarHBondContact O-N 2.78Å
341	K	88.9	Confident	85.1	Confident	62 Å²	62	71.2 Å²	71.2	27%	0.27	36%	0.359	S	S	.	.	H	α-helix	trans	-63.8	-40.8	178.4	-77.5	-165.6	-179.7	-163.8	0	113.2	D268 T269 T272 D337 V338 E343 L344 L345	D268-K341 IonicContact OD1-NZ 2.63Å; D268-K341 IonicContact OD2-NZ 3.04Å; D268-K341 PolarHBondContact OD2-NZ 3.42Å; T269-K341 HydrophobicContact CG2-CB 4.42Å; T272-K341 HydrophobicContact CG2-CD 3.93Å; T272-K341 PolarHBondContact OG1-NZ 3.49Å; D337-K341 WeakPolarHBondContact O-CB 3.46Å; D337-K341 WeakPolarHBondContact O-CG 3.3Å; D337-K341 PolarHBondContact O-N 3.24Å; V338-K341 PolarHBondContact O-N 3.17Å; K341-E343 VanDerWaalsContact C-N 3.34Å; K341-L344 PolarHBondContact O-N 2.72Å; K341-L345 WeakPolarHBondContact O-CB 2.99Å; K341-L345 PolarHBondContact O-N 3.05Å
342	L	87.2	Confident	84.6	Confident	20 Å²	20	72.4 Å²	72.4	11%	0.105	37%	0.366	C	S	.	.	H	α-helix	trans	-64	-41.4	176.4	-77.4	173.1	0	0	0	111.3	L172 R175 L179 T269 V338 L339 V340 L345 D346	L172-L342 HydrophobicContact CD2-CD1 3.83Å; R175-L342 HydrophobicContact CB-CD1 4.28Å; L179-L342 HydrophobicContact CD2-CD2 4.07Å; T269-L342 HydrophobicContact CG2-CD2 3.8Å; T269-L342 HydrophobicContact CG2-CG 4.31Å; V338-L342 HydrophobicContact CG1-CD1 3.79Å; V338-L342 HydrophobicContact CG1-CG 4.3Å; V338-L342 WeakPolarHBondContact O-CB 3.46Å; V338-L342 WeakPolarHBondContact O-CG 3.4Å; V338-L342 PolarHBondContact O-N 2.83Å; L339-L342 PolarHBondContact O-N 3.5Å; V340-L342 PolarHBondContact O-N 3.26Å; L342-L345 PolarHBondContact O-N 3.03Å; L342-D346 WeakPolarHBondContact O-CB 3.27Å; L342-D346 PolarHBondContact O-N 3.32Å
343	E	86.1	Confident	84.1	Confident	121 Å²	121	72 Å²	72	57%	0.565	36%	0.358	S	S	*	.	H	α-helix	trans	-64.1	-45.9	176.7	-173.5	174.6	-176.9	0	0	111.9	L339 V340 K341 L345 D346 Q347	L339-E343 WeakPolarHBondContact O-CB 3.32Å; L339-E343 PolarHBondContact O-N 2.68Å; V340-E343 PolarHBondContact O-N 3.2Å; K341-E343 VanDerWaalsContact C-N 3.34Å; E343-L345 VanDerWaalsContact C-N 3.3Å; E343-L345 PolarHBondContact O-N 3.48Å; E343-D346 PolarHBondContact O-N 3.41Å; E343-Q347 WeakPolarHBondContact O-CB 3.34Å; E343-Q347 WeakPolarHBondContact O-CG 3.32Å; E343-Q347 PolarHBondContact O-N 3.47Å; E343-Q347 PolarHBondContact OE1-NE2 3.29Å
344	L	86.2	Confident	83.7	Confident	104 Å²	104	68 Å²	68	55%	0.545	35%	0.352	S	S	.	.	H	α-helix	trans	-60.6	-39.8	175.6	-70.4	172.6	0	0	0	112.2	V340 K341 K348	V340-L344 HydrophobicContact CG1-CD1 4.03Å; V340-L344 HydrophobicContact CG1-CG 4.43Å; V340-L344 VanDerWaalsContact O-CG 3.31Å; V340-L344 WeakPolarHBondContact O-CG 3.32Å; V340-L344 PolarHBondContact O-N 2.78Å; K341-L344 PolarHBondContact O-N 2.72Å; L344-K348 WeakPolarHBondContact O-CB 3.31Å; L344-K348 PolarHBondContact O-N 3.06Å; L344-K348 VanDerWaalsContact O-N 3.16Å
345	L	85.5	Confident	83.5	Confident	13 Å²	13	73.4 Å²	73.4	7%	0.068	37%	0.371	C	S	.	.	H	α-helix	trans	-66.6	-42.4	177.4	-169.4	70.1	0	0	0	111.2	L179 Y261 A265 V266 T269 K341 L342 E343 K348 R349	L179-L345 HydrophobicContact CD1-CD2 3.59Å; L179-L345 HydrophobicContact CD2-CD2 4.04Å; L179-L345 HydrophobicContact CG-CD2 4.48Å; Y261-L345 HydrophobicContact CD2-CD1 4.24Å; Y261-L345 HydrophobicContact CE2-CD1 3.58Å; Y261-L345 HydrophobicContact CE2-CG 4.22Å; A265-L345 HydrophobicContact CB-CD1 3.93Å; V266-L345 HydrophobicContact CG2-CD2 4.43Å; T269-L345 HydrophobicContact CG2-CD2 4.08Å; K341-L345 WeakPolarHBondContact O-CB 2.99Å; K341-L345 PolarHBondContact O-N 3.05Å; L342-L345 PolarHBondContact O-N 3.03Å; E343-L345 VanDerWaalsContact C-N 3.3Å; E343-L345 PolarHBondContact O-N 3.48Å; L345-K348 PolarHBondContact O-N 3.38Å; L345-R349 WeakPolarHBondContact O-CB 3.48Å; L345-R349 PolarHBondContact O-N 2.85Å
346	D	81.7	Confident	83.4	Confident	79 Å²	79	70.1 Å²	70.1	42%	0.422	36%	0.359	S	S	.	.	H	α-helix	trans	-70.2	-40.8	-179	-162.9	36.8	0	0	0	112.5	L342 E343 K348 R349 V350	L342-D346 WeakPolarHBondContact O-CB 3.27Å; L342-D346 PolarHBondContact O-N 3.32Å; E343-D346 PolarHBondContact O-N 3.41Å; D346-K348 VanDerWaalsContact C-N 3.35Å; D346-K348 PolarHBondContact O-N 3.21Å; D346-R349 PolarHBondContact O-N 3.06Å; D346-R349 IonicContact OD1-CZ 3.3Å; D346-R349 VanDerWaalsContact OD1-CZ 3.26Å; D346-R349 IonicContact OD1-NE 2.65Å; D346-R349 PolarHBondContact OD1-NE 2.87Å; D346-R349 IonicContact OD1-NH2 2.98Å; D346-R349 PolarHBondContact OD1-NH2 3.02Å; D346-V350 PolarHBondContact O-N 2.89Å
347	Q	79.4	Confident	83.2	Confident	108 Å²	108	69.9 Å²	69.9	51%	0.505	35%	0.351	S	S	.	.	H	α-helix	trans	-58.6	-46.2	173.6	-74.2	179.1	2.3	0	0	111.5	E343	E343-Q347 WeakPolarHBondContact O-CB 3.34Å; E343-Q347 WeakPolarHBondContact O-CG 3.32Å; E343-Q347 PolarHBondContact O-N 3.47Å; E343-Q347 PolarHBondContact OE1-NE2 3.29Å
348	K	76.2	Confident	83.2	Confident	107 Å²	107	72.7 Å²	72.7	47%	0.465	36%	0.362	S	S	.	.	H	α-helix	trans	-65.6	-42	176.9	-168.4	177.1	-176.1	-176.6	0	111.4	L344 L345 D346 D352	L344-K348 WeakPolarHBondContact O-CB 3.31Å; L344-K348 PolarHBondContact O-N 3.06Å; L344-K348 VanDerWaalsContact O-N 3.16Å; L345-K348 PolarHBondContact O-N 3.38Å; D346-K348 VanDerWaalsContact C-N 3.35Å; D346-K348 PolarHBondContact O-N 3.21Å; K348-D352 WeakPolarHBondContact O-CB 3.39Å; K348-D352 PolarHBondContact O-N 3.33Å
349	R	73.6	Confident	83.3	Confident	60 Å²	60	75.8 Å²	75.8	23%	0.226	37%	0.374	C	S	.	.	H	α-helix	trans	-59.6	-52.1	-175.2	179.9	-173.8	72.8	95	-0.3	113.4	Y186 Y261 L345 D346 Q351 L353	Y186-R349 HydrophobicContact CE2-CG 4.38Å; Y186-R349 PolarHBondContact OH-NH1 3.3Å; Y186-R349 VanDerWaalsContact OH-NH1 3.08Å; Y261-R349 HydrophobicContact CE2-CB 4.35Å; Y261-R349 WeakPolarHBondContact OH-CD 3.38Å; Y261-R349 WeakPolarHBondContact OH-CG 3.47Å; L345-R349 WeakPolarHBondContact O-CB 3.48Å; L345-R349 PolarHBondContact O-N 2.85Å; D346-R349 PolarHBondContact O-N 3.06Å; D346-R349 IonicContact OD1-CZ 3.3Å; D346-R349 VanDerWaalsContact OD1-CZ 3.26Å; D346-R349 IonicContact OD1-NE 2.65Å; D346-R349 PolarHBondContact OD1-NE 2.87Å; D346-R349 IonicContact OD1-NH2 2.98Å; D346-R349 PolarHBondContact OD1-NH2 3.02Å; R349-Q351 PolarHBondContact O-N 3.25Å; R349-L353 VanDerWaalsContact O-CB 3.25Å; R349-L353 WeakPolarHBondContact O-CB 3.4Å; R349-L353 PolarHBondContact O-N 3.15Å
350	V	69.5	Low	83.4	Confident	86 Å²	86	73.9 Å²	73.9	52%	0.521	36%	0.363	S	S	.	.	H	α-helix	trans	-64.7	-43.4	-171.1	175.2	0	0	0	0	111.3	D346	D346-V350 PolarHBondContact O-N 2.89Å
351	Q	73.8	Confident	83.6	Confident	159 Å²	159	74.3 Å²	74.3	74%	0.743	37%	0.366	S	S	*	.	H	α-helix	trans	-73.9	-43.9	-179.2	-66	-178	-13.6	0	0	111.8	R349 Y355	R349-Q351 PolarHBondContact O-N 3.25Å; Q351-Y355 WeakPolarHBondContact O-CB 3.29Å; Q351-Y355 PolarHBondContact O-N 2.84Å
352	D	78.4	Confident	83.9	Confident	33 Å²	33	74 Å²	74	18%	0.176	37%	0.369	C	S	.	.	H	α-helix	trans	-72	-45.1	-174.2	-160.9	8	0	0	0	111.2	K348 A354 Y355 Q356	K348-D352 WeakPolarHBondContact O-CB 3.39Å; K348-D352 PolarHBondContact O-N 3.33Å; D352-A354 PolarHBondContact O-N 2.91Å; D352-Y355 WeakPolarHBondContact O-CB 3.19Å; D352-Y355 PolarHBondContact O-N 3.1Å; D352-Q356 VanDerWaalsContact O-CG 3.27Å; D352-Q356 WeakPolarHBondContact O-CG 3.49Å; D352-Q356 PolarHBondContact O-N 3.04Å; D352-Q356 PolarHBondContact OD1-NE2 2.94Å
353	L	78	Confident	84.2	Confident	38 Å²	38	73.8 Å²	73.8	20%	0.199	37%	0.37	C	S	.	.	H	α-helix	trans	-62	-50.6	-177.7	179.7	78.7	0	0	0	113.1	Y186 R349 Y355 Q356 L357	Y186-L353 HydrophobicContact CD1-CD1 3.69Å; Y186-L353 HydrophobicContact CD1-CD2 4.43Å; Y186-L353 HydrophobicContact CE1-CD1 3.4Å; Y186-L353 HydrophobicContact CE1-CD2 3.35Å; Y186-L353 HydrophobicContact CE1-CG 3.92Å; R349-L353 VanDerWaalsContact O-CB 3.25Å; R349-L353 WeakPolarHBondContact O-CB 3.4Å; R349-L353 PolarHBondContact O-N 3.15Å; L353-Y355 PolarHBondContact O-N 2.95Å; L353-Q356 PolarHBondContact O-N 3.46Å; L353-L357 HydrophobicContact CD1-CD1 4.42Å; L353-L357 HydrophobicContact CD1-CG 4.49Å; L353-L357 HydrophobicContact CD2-CD1 4.43Å; L353-L357 HydrophobicContact CG-CD1 4.09Å; L353-L357 HydrophobicContact CG-CG 4.46Å; L353-L357 WeakPolarHBondContact O-CB 3.48Å; L353-L357 PolarHBondContact O-N 3.42Å
354	A	83.9	Confident	84.6	Confident	62 Å²	62	69.7 Å²	69.7	51%	0.512	35%	0.351	S	S	.	.	H	α-helix	trans	-60.5	-38	-179.2	0	0	0	0	0	110.3	D352 H358	D352-A354 PolarHBondContact O-N 2.91Å; A354-H358 VanDerWaalsContact O-CB 3.31Å; A354-H358 WeakPolarHBondContact O-CB 3.33Å; A354-H358 PolarHBondContact O-N 3.31Å
355	Y	87.4	Confident	85	Confident	142 Å²	142	70.8 Å²	70.8	56%	0.557	35%	0.354	S	S	*	.	H	α-helix	trans	-63.8	-47.4	174.5	179	-101.8	0	0	0	112.5	Q351 D352 L353 H358 R359	Q351-Y355 WeakPolarHBondContact O-CB 3.29Å; Q351-Y355 PolarHBondContact O-N 2.84Å; D352-Y355 WeakPolarHBondContact O-CB 3.19Å; D352-Y355 PolarHBondContact O-N 3.1Å; L353-Y355 PolarHBondContact O-N 2.95Å; Y355-H358 PolarHBondContact O-N 3.35Å; Y355-R359 WeakPolarHBondContact O-CB 3.15Å; Y355-R359 PolarHBondContact O-N 3.44Å
356	Q	86	Confident	85.5	Confident	3 Å²	3	76.7 Å²	76.7	1%	0.014	38%	0.379	C	S	.	.	H	α-helix	trans	-66	-39.7	178.8	-63.4	-52	-18.4	0	0	112.4	M254 D257 L258 D352 L353 R359 F360	M254-Q356 HydrophobicContact CG-CB 3.74Å; M254-Q356 HydrophobicContact CG-CG 4.11Å; D257-Q356 PolarHBondContact OD2-NE2 3.16Å; L258-Q356 HydrophobicContact CD1-CB 4.14Å; L258-Q356 HydrophobicContact CD1-CG 4.44Å; L258-Q356 HydrophobicContact CD2-CB 4.4Å; L258-Q356 HydrophobicContact CD2-CG 4.22Å; L258-Q356 HydrophobicContact CG-CB 4.39Å; L258-Q356 HydrophobicContact CG-CG 4.18Å; D352-Q356 VanDerWaalsContact O-CG 3.27Å; D352-Q356 WeakPolarHBondContact O-CG 3.49Å; D352-Q356 PolarHBondContact O-N 3.04Å; D352-Q356 PolarHBondContact OD1-NE2 2.94Å; L353-Q356 PolarHBondContact O-N 3.46Å; Q356-R359 PolarHBondContact O-N 2.87Å; Q356-F360 WeakPolarHBondContact O-CB 3.12Å; Q356-F360 PolarHBondContact O-N 3.13Å
357	L	87	Confident	86.1	Confident	63 Å²	63	73.4 Å²	73.4	33%	0.33	36%	0.361	S	S	.	.	H	α-helix	trans	-64.5	-43.2	175	-78.9	177.4	0	0	0	111.9	L189 L353 F360 V361	L189-L357 HydrophobicContact CD2-CD2 3.9Å; L353-L357 HydrophobicContact CD1-CD1 4.42Å; L353-L357 HydrophobicContact CD1-CG 4.49Å; L353-L357 HydrophobicContact CD2-CD1 4.43Å; L353-L357 HydrophobicContact CG-CD1 4.09Å; L353-L357 HydrophobicContact CG-CG 4.46Å; L353-L357 WeakPolarHBondContact O-CB 3.48Å; L353-L357 PolarHBondContact O-N 3.42Å; L357-F360 WeakPolarHBondContact O-CB 3.4Å; L357-F360 PolarHBondContact O-N 3Å; L357-V361 WeakPolarHBondContact O-CG2 3.47Å; L357-V361 PolarHBondContact O-N 3.29Å
358	H	90.7	Very high	86.8	Confident	125 Å²	125	73 Å²	73	58%	0.579	36%	0.359	S	S	*	.	H	α-helix	trans	-61.2	-47.4	175.1	-178	62.4	0	0	0	110.8	A354 Y355 F360 V361 T362	A354-H358 VanDerWaalsContact O-CB 3.31Å; A354-H358 WeakPolarHBondContact O-CB 3.33Å; A354-H358 PolarHBondContact O-N 3.31Å; Y355-H358 PolarHBondContact O-N 3.35Å; H358-F360 VanDerWaalsContact C-N 3.27Å; H358-F360 PolarHBondContact O-N 3.4Å; H358-V361 PolarHBondContact O-N 3.03Å; H358-T362 WeakPolarHBondContact O-CB 3.06Å; H358-T362 PolarHBondContact O-N 3.42Å; H358-T362 PolarHBondContact O-OG1 2.95Å; H358-T362 VanDerWaalsContact O-OG1 3.05Å
359	R	91	Very high	87.7	Confident	67 Å²	67	70.7 Å²	70.7	25%	0.253	36%	0.356	S	S	.	.	H	α-helix	trans	-56.9	-40	175.8	-176	179	168.1	178.9	4.2	112.4	N250 P253 Y355 Q356 A363	N250-R359 PolarHBondContact O-NE 3.5Å; N250-R359 PolarHBondContact O-NH2 3.11Å; P253-R359 VanDerWaalsContact CG-NH2 3.28Å; Y355-R359 WeakPolarHBondContact O-CB 3.15Å; Y355-R359 PolarHBondContact O-N 3.44Å; Q356-R359 PolarHBondContact O-N 2.87Å; R359-A363 VanDerWaalsContact O-CB 3.3Å; R359-A363 WeakPolarHBondContact O-CB 3.35Å; R359-A363 PolarHBondContact O-N 2.9Å
360	F	91.8	Very high	88.8	Confident	24 Å²	24	68 Å²	68	11%	0.105	35%	0.346	C	S	.	.	H	α-helix	trans	-63.2	-52.3	175.4	178.5	-111.9	0	0	0	112.4	I193 L196 L251 M254 Q356 L357 H358 T362 A363 I364	I193-F360 HydrophobicContact CB-CZ 4.46Å; I193-F360 HydrophobicContact CD1-CE1 4.5Å; I193-F360 HydrophobicContact CD1-CZ 4.49Å; I193-F360 HydrophobicContact CG1-CE1 4.18Å; I193-F360 HydrophobicContact CG1-CE2 4.23Å; I193-F360 HydrophobicContact CG1-CZ 3.88Å; I193-F360 HydrophobicContact CG2-CD2 4.26Å; I193-F360 HydrophobicContact CG2-CE2 3.71Å; I193-F360 HydrophobicContact CG2-CZ 4.13Å; L196-F360 HydrophobicContact CD2-CZ 3.81Å; L251-F360 HydrophobicContact CD1-CD2 3.9Å; L251-F360 HydrophobicContact CD1-CE2 4.05Å; L251-F360 HydrophobicContact CD2-CD2 3.96Å; M254-F360 HydrophobicContact CE-CB 3.85Å; M254-F360 HydrophobicContact CE-CD2 3.61Å; M254-F360 HydrophobicContact CE-CG 4.12Å; Q356-F360 WeakPolarHBondContact O-CB 3.12Å; Q356-F360 PolarHBondContact O-N 3.13Å; L357-F360 WeakPolarHBondContact O-CB 3.4Å; L357-F360 PolarHBondContact O-N 3Å; H358-F360 VanDerWaalsContact C-N 3.27Å; H358-F360 PolarHBondContact O-N 3.4Å; F360-T362 PolarHBondContact O-N 3.31Å; F360-A363 PolarHBondContact O-N 3.21Å; F360-I364 HydrophobicContact CD1-CD1 4.04Å; F360-I364 HydrophobicContact CD2-CD1 4.12Å; F360-I364 HydrophobicContact CE1-CD1 3.47Å; F360-I364 VanDerWaalsContact CE1-CD1 3.47Å; F360-I364 HydrophobicContact CE2-CD1 3.56Å; F360-I364 HydrophobicContact CE2-CG1 4.34Å; F360-I364 HydrophobicContact CG-CD1 4.37Å; F360-I364 HydrophobicContact CZ-CD1 3.24Å; F360-I364 HydrophobicContact CZ-CG1 4.43Å; F360-I364 PolarHBondContact O-N 3.43Å
361	V	93.3	Very high	89.9	Confident	85 Å²	85	64.2 Å²	64.2	52%	0.515	32%	0.324	S	S	.	.	H	α-helix	trans	-61.4	-46.4	-179.3	172.9	0	0	0	0	110.9	L357 H358 A363 I364 E365	L357-V361 WeakPolarHBondContact O-CG2 3.47Å; L357-V361 PolarHBondContact O-N 3.29Å; H358-V361 PolarHBondContact O-N 3.03Å; V361-A363 VanDerWaalsContact C-N 3.3Å; V361-A363 PolarHBondContact O-N 2.76Å; V361-I364 PolarHBondContact O-N 3.05Å; V361-E365 WeakPolarHBondContact O-CB 3.17Å; V361-E365 PolarHBondContact O-N 3.09Å
362	T	95.1	Very high	90.8	Very high	56 Å²	56	63 Å²	63	34%	0.344	32%	0.317	S	S	.	.	H	α-helix	trans	-62.3	-36.8	178.2	-61.2	0	0	0	0	112.2	H358 F360 K366	H358-T362 WeakPolarHBondContact O-CB 3.06Å; H358-T362 PolarHBondContact O-N 3.42Å; H358-T362 PolarHBondContact O-OG1 2.95Å; H358-T362 VanDerWaalsContact O-OG1 3.05Å; F360-T362 PolarHBondContact O-N 3.31Å; T362-K366 VanDerWaalsContact O-CB 3.3Å; T362-K366 WeakPolarHBondContact O-CB 3.3Å; T362-K366 PolarHBondContact O-N 2.86Å
363	A	93.8	Very high	91.6	Very high	15 Å²	15	67 Å²	67	12%	0.124	33%	0.334	C	S	.	.	H	α-helix	trans	-67.6	-43	176.7	0	0	0	0	0	111.7	L247 L251 R359 F360 V361 K366 Y367	L247-A363 HydrophobicContact CD1-CB 3.66Å; L247-A363 WeakPolarHBondContact CD1-O 3.39Å; L251-A363 HydrophobicContact CD2-CB 3.6Å; L251-A363 HydrophobicContact CG-CB 4.19Å; R359-A363 VanDerWaalsContact O-CB 3.3Å; R359-A363 WeakPolarHBondContact O-CB 3.35Å; R359-A363 PolarHBondContact O-N 2.9Å; F360-A363 PolarHBondContact O-N 3.21Å; V361-A363 VanDerWaalsContact C-N 3.3Å; V361-A363 PolarHBondContact O-N 2.76Å; A363-K366 PolarHBondContact O-N 3.02Å; A363-Y367 WeakPolarHBondContact O-CB 3.43Å; A363-Y367 PolarHBondContact O-N 2.83Å
364	I	93.8	Very high	92.3	Very high	34 Å²	34	66.1 Å²	66.1	17%	0.174	33%	0.33	C	S	.	.	H	α-helix	trans	-64.7	-43.8	175.9	-72.1	177.7	0	0	0	111.4	L196 L247 F360 V361 K366 Y367 H368	L196-I364 HydrophobicContact CD2-CD1 4.09Å; L247-I364 HydrophobicContact CD1-CG1 4.39Å; F360-I364 HydrophobicContact CD1-CD1 4.04Å; F360-I364 HydrophobicContact CD2-CD1 4.12Å; F360-I364 HydrophobicContact CE1-CD1 3.47Å; F360-I364 VanDerWaalsContact CE1-CD1 3.47Å; F360-I364 HydrophobicContact CE2-CD1 3.56Å; F360-I364 HydrophobicContact CE2-CG1 4.34Å; F360-I364 HydrophobicContact CG-CD1 4.37Å; F360-I364 HydrophobicContact CZ-CD1 3.24Å; F360-I364 HydrophobicContact CZ-CG1 4.43Å; F360-I364 PolarHBondContact O-N 3.43Å; V361-I364 PolarHBondContact O-N 3.05Å; I364-K366 VanDerWaalsContact C-N 3.34Å; I364-K366 PolarHBondContact O-N 3.14Å; I364-Y367 WeakPolarHBondContact O-CB 3.44Å; I364-Y367 PolarHBondContact O-N 2.92Å; I364-H368 VanDerWaalsContact CG2-CD2 3.49Å; I364-H368 WeakPolarHBondContact CG2-CD2 3.21Å; I364-H368 PolarHBondContact O-CD2 3.07Å; I364-H368 PolarHBondContact O-N 2.93Å
365	E	95.6	Very high	92.6	Very high	128 Å²	128	67.6 Å²	67.6	60%	0.598	33%	0.327	S	S	*	.	H	α-helix	trans	-57.1	-48.7	175.4	-179.4	-172.7	-177.9	0	0	110.8	V361 Y367 H368 S369	V361-E365 WeakPolarHBondContact O-CB 3.17Å; V361-E365 PolarHBondContact O-N 3.09Å; E365-Y367 VanDerWaalsContact C-N 3.32Å; E365-Y367 PolarHBondContact O-N 2.92Å; E365-H368 PolarHBondContact O-N 3.4Å; E365-S369 VanDerWaalsContact O-CB 3.3Å; E365-S369 WeakPolarHBondContact O-CB 3.24Å; E365-S369 PolarHBondContact O-N 3.18Å
366	K	95.4	Very high	92.8	Very high	137 Å²	137	64.5 Å²	64.5	60%	0.596	32%	0.318	S	S	*	.	H	α-helix	trans	-62.4	-38.6	178.2	-173.4	176.6	-178.1	174.7	0	112.4	T362 A363 I364 G370	T362-K366 VanDerWaalsContact O-CB 3.3Å; T362-K366 WeakPolarHBondContact O-CB 3.3Å; T362-K366 PolarHBondContact O-N 2.86Å; A363-K366 PolarHBondContact O-N 3.02Å; I364-K366 VanDerWaalsContact C-N 3.34Å; I364-K366 PolarHBondContact O-N 3.14Å; K366-G370 PolarHBondContact O-N 2.73Å
367	Y	94.4	Very high	92.9	Very high	9 Å²	9	68.2 Å²	68.2	4%	0.035	34%	0.342	C	S	.	.	H	α-helix	trans	-61.3	-56.5	174.6	167.5	-105.6	0	0	0	111	H200 R243 A244 L247 A363 I364 E365 S369 G370 C371	H200-Y367 AromaticContact CD2-CE1 3.99Å; R243-Y367 HydrophobicContact CB-CD2 3.93Å; R243-Y367 HydrophobicContact CB-CE2 4.09Å; A244-Y367 HydrophobicContact CB-CE2 3.75Å; L247-Y367 HydrophobicContact CB-CD2 4.39Å; L247-Y367 HydrophobicContact CD2-CD1 4.12Å; L247-Y367 HydrophobicContact CD2-CD2 4.34Å; L247-Y367 HydrophobicContact CD2-CG 3.91Å; A363-Y367 WeakPolarHBondContact O-CB 3.43Å; A363-Y367 PolarHBondContact O-N 2.83Å; I364-Y367 WeakPolarHBondContact O-CB 3.44Å; I364-Y367 PolarHBondContact O-N 2.92Å; E365-Y367 VanDerWaalsContact C-N 3.32Å; E365-Y367 PolarHBondContact O-N 2.92Å; Y367-S369 PolarHBondContact O-N 3.25Å; Y367-G370 PolarHBondContact O-N 3.45Å; Y367-G370 VanDerWaalsContact O-N 3.14Å; Y367-C371 WeakPolarHBondContact CE2-SG 3.09Å; Y367-C371 PolarHBondContact O-N 2.89Å; Y367-C371 PolarHBondContact O-SG 3.32Å
368	H	94.3	Very high	92.8	Very high	100 Å²	100	66.2 Å²	66.2	46%	0.463	33%	0.332	S	S	.	.	H	α-helix	trans	-66.6	-37.2	-177.3	-72.2	-58.7	0	0	0	113.6	I364 E365 G370 C371 K372	I364-H368 VanDerWaalsContact CG2-CD2 3.49Å; I364-H368 WeakPolarHBondContact CG2-CD2 3.21Å; I364-H368 PolarHBondContact O-CD2 3.07Å; I364-H368 PolarHBondContact O-N 2.93Å; E365-H368 PolarHBondContact O-N 3.4Å; H368-G370 VanDerWaalsContact C-N 3.3Å; H368-G370 PolarHBondContact O-N 3.33Å; H368-C371 PolarHBondContact O-N 2.83Å; H368-K372 PolarHBondContact O-N 2.92Å
369	S	95.9	Very high	92.3	Very high	58 Å²	58	68 Å²	68	41%	0.406	33%	0.334	S	S	.	.	H	α-helix	trans	-61.6	-41.7	172.5	-169.2	0	0	0	0	111	E365 Y367 K372 E373	E365-S369 VanDerWaalsContact O-CB 3.3Å; E365-S369 WeakPolarHBondContact O-CB 3.24Å; E365-S369 PolarHBondContact O-N 3.18Å; Y367-S369 PolarHBondContact O-N 3.25Å; S369-K372 WeakPolarHBondContact O-CB 3.13Å; S369-K372 PolarHBondContact O-N 3.48Å; S369-E373 WeakPolarHBondContact O-CG 3.44Å; S369-E373 PolarHBondContact O-N 3.15Å
370	G	95	Very high	91.7	Very high	3 Å²	3	72.2 Å²	72.2	3%	0.031	36%	0.361	C	S	.	.	H	α-helix	trans	-63.8	-45	176.2	0	0	0	0	0	112.9	R243 K366 Y367 H368 K372 E373 D374	R243-G370 PolarHBondContact NE-O 3.18Å; K366-G370 PolarHBondContact O-N 2.73Å; Y367-G370 PolarHBondContact O-N 3.45Å; Y367-G370 VanDerWaalsContact O-N 3.14Å; H368-G370 VanDerWaalsContact C-N 3.3Å; H368-G370 PolarHBondContact O-N 3.33Å; G370-K372 VanDerWaalsContact C-N 3.26Å; G370-K372 PolarHBondContact O-N 3.4Å; G370-E373 WeakPolarHBondContact O-CB 3.36Å; G370-E373 PolarHBondContact O-N 3.45Å; G370-E373 VanDerWaalsContact O-N 3.16Å; G370-D374 VanDerWaalsContact O-CG 3.32Å; G370-D374 PolarHBondContact O-N 3.3Å
371	C	93.7	Very high	91.1	Very high	8 Å²	8	72.5 Å²	72.5	5%	0.054	36%	0.364	C	S	.	.	H	α-helix	trans	-62	-36.9	175.7	-62.7	0	0	0	0	111.7	M240 Y367 H368 D374 M375	M240-C371 HydrophobicContact CE-CB 4.05Å; M240-C371 HydrophobicContact CG-CB 4.19Å; Y367-C371 WeakPolarHBondContact CE2-SG 3.09Å; Y367-C371 PolarHBondContact O-N 2.89Å; Y367-C371 PolarHBondContact O-SG 3.32Å; H368-C371 PolarHBondContact O-N 2.83Å; C371-D374 PolarHBondContact O-N 3.36Å; C371-M375 VanDerWaalsContact O-CG 3.24Å; C371-M375 WeakPolarHBondContact O-CG 3.32Å; C371-M375 PolarHBondContact O-N 3.12Å
372	K	93.4	Very high	90.3	Very high	134 Å²	134	75.3 Å²	75.3	58%	0.583	37%	0.37	S	S	*	.	H	α-helix	trans	-62.1	-43.6	174.5	-178.7	-170	172.7	-169.5	0	111.6	H368 S369 G370 M375 E376	H368-K372 PolarHBondContact O-N 2.92Å; S369-K372 WeakPolarHBondContact O-CB 3.13Å; S369-K372 PolarHBondContact O-N 3.48Å; G370-K372 VanDerWaalsContact C-N 3.26Å; G370-K372 PolarHBondContact O-N 3.4Å; K372-M375 PolarHBondContact O-N 3.35Å; K372-E376 PolarHBondContact O-N 3.37Å
373	E	94.2	Very high	89.4	Confident	116 Å²	116	77.9 Å²	77.9	54%	0.542	39%	0.387	S	S	.	.	H	α-helix	trans	-62.1	-43.5	175.4	-71.5	166.2	-167.3	0	0	111.5	S369 G370 M375 E376	S369-E373 WeakPolarHBondContact O-CG 3.44Å; S369-E373 PolarHBondContact O-N 3.15Å; G370-E373 WeakPolarHBondContact O-CB 3.36Å; G370-E373 PolarHBondContact O-N 3.45Å; G370-E373 VanDerWaalsContact O-N 3.16Å; E373-M375 PolarHBondContact O-N 2.77Å; E373-E376 WeakPolarHBondContact O-CB 3.34Å; E373-E376 PolarHBondContact O-N 3.39Å; E373-E376 VanDerWaalsContact O-N 3.13Å
374	D	92.8	Very high	88.5	Confident	20 Å²	20	79.2 Å²	79.2	11%	0.107	39%	0.392	C	S	.	.	H	α-helix	trans	-62.3	-30	176.6	-64.1	-17.9	0	0	0	112.1	V236 N239 R243 G370 C371 P377	V236-D374 HydrophobicContact CG1-CB 4.33Å; V236-D374 WeakPolarHBondContact CG2-O 3.46Å; N239-D374 HydrophobicContact CB-CB 4.47Å; R243-D374 WeakPolarHBondContact CD-OD2 3.5Å; R243-D374 IonicContact CZ-OD1 2.77Å; R243-D374 IonicContact CZ-OD2 3.12Å; R243-D374 VanDerWaalsContact NE-CG 3.26Å; R243-D374 IonicContact NE-OD1 2.84Å; R243-D374 PolarHBondContact NE-OD1 2.78Å; R243-D374 IonicContact NE-OD2 3.8Å; R243-D374 PolarHBondContact NE-OD2 3.06Å; R243-D374 IonicContact NH2-OD1 3.16Å; R243-D374 PolarHBondContact NH2-OD1 3.4Å; R243-D374 IonicContact NH2-OD2 2.75Å; G370-D374 VanDerWaalsContact O-CG 3.32Å; G370-D374 PolarHBondContact O-N 3.3Å; C371-D374 PolarHBondContact O-N 3.36Å; D374-P377 WeakPolarHBondContact O-CD 3.44Å
375	M	90.9	Very high	87.5	Confident	93 Å²	93	82.5 Å²	82.5	46%	0.458	41%	0.409	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.6	-8.3	178	-69	176.5	76.8	0	0	114	V236 C371 K372 E373 P377 T378	V236-M375 HydrophobicContact CG1-CG 3.9Å; C371-M375 VanDerWaalsContact O-CG 3.24Å; C371-M375 WeakPolarHBondContact O-CG 3.32Å; C371-M375 PolarHBondContact O-N 3.12Å; K372-M375 PolarHBondContact O-N 3.35Å; E373-M375 PolarHBondContact O-N 2.77Å; M375-P377 VanDerWaalsContact C-CD 3.46Å; M375-T378 PolarHBondContact O-N 2.76Å; M375-T378 VanDerWaalsContact O-N 3.17Å; M375-T378 PolarHBondContact O-OG1 3.26Å
376	E	90.7	Very high	86.2	Confident	77 Å²	77	79.2 Å²	79.2	36%	0.36	40%	0.398	S	S	.	.	G	3₁₀ helix	trans	-58.2	-41.8	179.4	-71.9	-65	146.6	0	0	114.1	K372 E373 T378 R379	K372-E376 PolarHBondContact O-N 3.37Å; E373-E376 WeakPolarHBondContact O-CB 3.34Å; E373-E376 PolarHBondContact O-N 3.39Å; E373-E376 VanDerWaalsContact O-N 3.13Å; E376-T378 PolarHBondContact O-N 3.01Å; E376-T378 VanDerWaalsContact O-N 3.16Å; E376-R379 VanDerWaalsContact CD-NH2 3.28Å; E376-R379 PolarHBondContact O-N 3.48Å; E376-R379 IonicContact OE1-CZ 3.57Å; E376-R379 IonicContact OE1-NE 2.75Å; E376-R379 IonicContact OE1-NH2 3.49Å; E376-R379 PolarHBondContact OE1-NH2 2.92Å; E376-R379 IonicContact OE2-CZ 2.92Å; E376-R379 IonicContact OE2-NE 3.69Å; E376-R379 PolarHBondContact OE2-NE 2.63Å; E376-R379 IonicContact OE2-NH1 2.81Å; E376-R379 PolarHBondContact OE2-NH1 3.05Å; E376-R379 IonicContact OE2-NH2 2.72Å; E376-R379 PolarHBondContact OE2-NH2 3.45Å; E376-R379 VanDerWaalsContact OE2-NH2 3.12Å
377	P	87.5	Confident	84.8	Confident	80 Å²	80	76 Å²	76	52%	0.519	39%	0.388	S	S	.	.	G	3₁₀ helix	trans	-59.5	-24.7	176.7	-23.7	35.6	0	0	0	113.8	T232 D374 M375 R379	T232-P377 HydrophobicContact CG2-CB 3.93Å; D374-P377 WeakPolarHBondContact O-CD 3.44Å; M375-P377 VanDerWaalsContact C-CD 3.46Å; P377-R379 VanDerWaalsContact C-N 3.29Å; P377-R379 PolarHBondContact O-N 2.64Å
378	T	85.1	Confident	83.4	Confident	21 Å²	21	82.1 Å²	82.1	13%	0.129	42%	0.42	C	S	.	.	G	3₁₀ helix	trans	-78.8	-9.3	-175.4	74.7	0	0	0	0	113.9	T232 F233 V236 M375 E376 N380 L381	T232-T378 HydrophobicContact CG2-CG2 4.46Å; F233-T378 HydrophobicContact CD1-CG2 4Å; F233-T378 HydrophobicContact CE1-CG2 3.92Å; V236-T378 HydrophobicContact CB-CG2 4.47Å; V236-T378 HydrophobicContact CG2-CG2 3.75Å; M375-T378 PolarHBondContact O-N 2.76Å; M375-T378 VanDerWaalsContact O-N 3.17Å; M375-T378 PolarHBondContact O-OG1 3.26Å; E376-T378 PolarHBondContact O-N 3.01Å; E376-T378 VanDerWaalsContact O-N 3.16Å; T378-N380 VanDerWaalsContact C-N 3.28Å; T378-N380 PolarHBondContact O-N 3.22Å; T378-L381 HydrophobicContact CG2-CD1 4.2Å; T378-L381 PolarHBondContact O-N 3.31Å
379	R	80.9	Confident	81.9	Confident	163 Å²	163	81.2 Å²	81.2	62%	0.615	43%	0.425	S	S	*	.	G	3₁₀ helix	trans	-62.6	-30.8	-173.6	-75.1	-174.2	-178.6	-173.8	9.4	114.2	E376 P377	E376-R379 VanDerWaalsContact CD-NH2 3.28Å; E376-R379 PolarHBondContact O-N 3.48Å; E376-R379 IonicContact OE1-CZ 3.57Å; E376-R379 IonicContact OE1-NE 2.75Å; E376-R379 IonicContact OE1-NH2 3.49Å; E376-R379 PolarHBondContact OE1-NH2 2.92Å; E376-R379 IonicContact OE2-CZ 2.92Å; E376-R379 IonicContact OE2-NE 3.69Å; E376-R379 PolarHBondContact OE2-NE 2.63Å; E376-R379 IonicContact OE2-NH1 2.81Å; E376-R379 PolarHBondContact OE2-NH1 3.05Å; E376-R379 IonicContact OE2-NH2 2.72Å; E376-R379 PolarHBondContact OE2-NH2 3.45Å; E376-R379 VanDerWaalsContact OE2-NH2 3.12Å; P377-R379 VanDerWaalsContact C-N 3.29Å; P377-R379 PolarHBondContact O-N 2.64Å
380	N	79.1	Confident	79.8	Confident	155 Å²	155	83.4 Å²	83.4	83%	0.829	43%	0.432	S	S	*	.	G	3₁₀ helix	trans	-109.7	11.7	-173.6	-62.2	-27.8	0	0	0	113.3	T378 F382	T378-N380 VanDerWaalsContact C-N 3.28Å; T378-N380 PolarHBondContact O-N 3.22Å; N380-F382 VanDerWaalsContact C-N 3.28Å; N380-F382 PolarHBondContact O-N 3.27Å
381	L	79.2	Confident	77.7	Confident	31 Å²	31	87.6 Å²	87.6	16%	0.162	45%	0.453	C	S	.	.			trans	-78.6	-9.7	-178.4	-64.7	178.6	0	0	0	113.7	A229 T232 F233 T378 I384	A229-L381 HydrophobicContact CB-CB 4.15Å; A229-L381 HydrophobicContact CB-CD1 4.33Å; A229-L381 HydrophobicContact CB-CD2 4.09Å; A229-L381 HydrophobicContact CB-CG 4.42Å; T232-L381 HydrophobicContact CG2-CD1 3.84Å; F233-L381 HydrophobicContact CD2-CD1 4.22Å; F233-L381 HydrophobicContact CE1-CD1 4.23Å; F233-L381 HydrophobicContact CE2-CB 4.35Å; F233-L381 HydrophobicContact CE2-CD1 3.78Å; F233-L381 HydrophobicContact CZ-CB 4.29Å; F233-L381 HydrophobicContact CZ-CD1 3.79Å; T378-L381 HydrophobicContact CG2-CD1 4.2Å; T378-L381 PolarHBondContact O-N 3.31Å; L381-I384 VanDerWaalsContact O-CG1 3.3Å; L381-I384 WeakPolarHBondContact O-CG1 3.43Å
382	F	75	Confident	75.8	Confident	144 Å²	144	90.6 Å²	90.6	63%	0.632	48%	0.478	S	S	*	.			trans	-101.1	143.6	-178.3	-72.9	-81.9	0	0	0	112.5	F233 N380 I384	F233-F382 AromaticContact CZ-CE2 3.8Å; F233-F382 HydrophobicContact CZ-CE2 3.8Å; F233-F382 AromaticContact CZ-CZ 3.97Å; F233-F382 HydrophobicContact CZ-CZ 3.97Å; N380-F382 VanDerWaalsContact C-N 3.28Å; N380-F382 PolarHBondContact O-N 3.27Å; F382-I384 HydrophobicContact CD1-CD1 4.28Å; F382-I384 HydrophobicContact CD1-CG1 4.15Å; F382-I384 HydrophobicContact CE1-CD1 3.84Å; F382-I384 HydrophobicContact CE1-CG1 4.2Å; F382-I384 HydrophobicContact CZ-CD1 4.18Å
383	P	77.1	Confident	73.8	Confident	110 Å²	110	92.8 Å²	92.8	71%	0.714	49%	0.488	S	S	*	.	S	Bend	cis	-79.7	150.2	0.9	32.1	-34.3	0	0	0	113.6
384	I	74.2	Confident	71.6	Confident	42 Å²	42	93.9 Å²	93.9	22%	0.215	50%	0.497	C	S	.	.			trans	-101.2	113	173.6	-52	168.4	0	0	0	106.9	A229 F230 F233 L381 F382 V386	A229-I384 HydrophobicContact CB-CD1 4.17Å; A229-I384 HydrophobicContact CB-CG1 4.13Å; F230-I384 HydrophobicContact CE2-CG2 4.43Å; F230-I384 HydrophobicContact CZ-CG2 4.42Å; F233-I384 HydrophobicContact CE2-CD1 3.66Å; F233-I384 HydrophobicContact CZ-CD1 4.4Å; L381-I384 VanDerWaalsContact O-CG1 3.3Å; L381-I384 WeakPolarHBondContact O-CG1 3.43Å; F382-I384 HydrophobicContact CD1-CD1 4.28Å; F382-I384 HydrophobicContact CD1-CG1 4.15Å; F382-I384 HydrophobicContact CE1-CD1 3.84Å; F382-I384 HydrophobicContact CE1-CG1 4.2Å; F382-I384 HydrophobicContact CZ-CD1 4.18Å; I384-V386 HydrophobicContact CG2-CG2 3.84Å
385	D	74.2	Confident	69.2	Low	103 Å²	103	103.2 Å²	103.2	55%	0.551	53%	0.533	S	S	*	.			trans	-87.5	116.7	174.1	-66.6	-41.8	0	0	0	108.4	Q223 S226	Q223-D385 PolarHBondContact OE1-O 3.09Å; S226-D385 PolarHBondContact OG-O 3.34Å
386	V	67.2	Low	67.5	Low	60 Å²	60	104.2 Å²	104.2	36%	0.364	54%	0.54	S	S	.	.			trans	-115.4	116.3	177.1	-176.8	0	0	0	0	108.1	F230 I384 L388	F230-V386 HydrophobicContact CE2-CG2 4.1Å; F230-V386 HydrophobicContact CZ-CG2 3.95Å; I384-V386 HydrophobicContact CG2-CG2 3.84Å; V386-L388 PolarHBondContact O-N 3.16Å; V386-L388 VanDerWaalsContact O-N 3.16Å
387	D	65.9	Low	65.7	Low	69 Å²	69	106.3 Å²	106.3	37%	0.369	56%	0.56	S	S	.	*			trans	-85.5	85.6	177.1	-166.2	-10.5	0	0	0	110.9	S389 L390	D387-S389 PolarHBondContact O-N 2.6Å; D387-S389 VanDerWaalsContact O-N 3.09Å; D387-S389 VanDerWaalsContact OD1-CB 3.32Å; D387-S389 WeakPolarHBondContact OD1-CB 3.09Å; D387-S389 PolarHBondContact OD1-N 2.88Å; D387-S389 PolarHBondContact OD1-OG 3.46Å; D387-L390 HydrophobicContact CB-CD1 4.16Å; D387-L390 PolarHBondContact O-N 2.85Å; D387-L390 WeakPolarHBondContact OD2-CD1 3.35Å
388	L	65.1	Low	64.5	Low	137 Å²	137	106 Å²	106	72%	0.717	56%	0.56	S	S	*	*	H	α-helix	trans	-58.2	-20.3	176.2	-76.2	147.7	0	0	0	113.4	V386 L390 A392	V386-L388 PolarHBondContact O-N 3.16Å; V386-L388 VanDerWaalsContact O-N 3.16Å; L388-L390 VanDerWaalsContact C-N 3.33Å; L388-L390 PolarHBondContact O-N 3.41Å; L388-A392 WeakPolarHBondContact O-CB 3.12Å; L388-A392 PolarHBondContact O-N 3.48Å
389	S	62.8	Low	62.9	Low	82 Å²	82	108.6 Å²	108.6	57%	0.573	59%	0.591	S	S	*	*	H	α-helix	trans	-74	-24.7	-175.2	75.5	0	0	0	0	113.3	D387	D387-S389 PolarHBondContact O-N 2.6Å; D387-S389 VanDerWaalsContact O-N 3.09Å; D387-S389 VanDerWaalsContact OD1-CB 3.32Å; D387-S389 WeakPolarHBondContact OD1-CB 3.09Å; D387-S389 PolarHBondContact OD1-N 2.88Å; D387-S389 PolarHBondContact OD1-OG 3.46Å
390	L	52.3	Low	61	Low	104 Å²	104	109 Å²	109	55%	0.545	60%	0.6	S	S	.	*	H	α-helix	trans	-82.9	-25.3	179.7	-82.1	156.7	0	0	0	113.5	D387 L388	D387-L390 HydrophobicContact CB-CD1 4.16Å; D387-L390 PolarHBondContact O-N 2.85Å; D387-L390 WeakPolarHBondContact OD2-CD1 3.35Å; L388-L390 VanDerWaalsContact C-N 3.33Å; L388-L390 PolarHBondContact O-N 3.41Å
391	I	51.5	Low	59.4	Low	91 Å²	91	107.7 Å²	107.7	47%	0.467	59%	0.592	S	S	.	*	H	α-helix	trans	-102.4	-25.1	-171.3	-39	174.9	0	0	0	112	F393	I391-F393 PolarHBondContact O-N 2.97Å; I391-F393 VanDerWaalsContact O-N 3.1Å
392	A	52.4	Low	57.7	Low	71 Å²	71	110.5 Å²	110.5	59%	0.587	61%	0.612	S	S	*	*	S	Bend	trans	-65.5	-15.3	-175.3	0	0	0	0	0	115	L388	L388-A392 WeakPolarHBondContact O-CB 3.12Å; L388-A392 PolarHBondContact O-N 3.48Å
393	F	52.7	Low	56.2	Low	179 Å²	179	108.5 Å²	108.5	79%	0.785	62%	0.622	S	S	*	*	S	Bend	trans	-126.5	-13.6	-171.2	-63.7	-71.4	0	0	0	116.2	I391 Y395	I391-F393 PolarHBondContact O-N 2.97Å; I391-F393 VanDerWaalsContact O-N 3.1Å; F393-Y395 PolarHBondContact O-N 3.02Å
394	D	47.4	Very low	54.8	Low	140 Å²	140	109.6 Å²	109.6	75%	0.749	62%	0.622	S	S	*	*			trans	-98.3	76.2	176.8	-75.5	-22.6	0	0	0	110.6	N396	D394-N396 PolarHBondContact O-N 3.33Å
395	Y	42.9	Very low	53.4	Low	216 Å²	216	110.9 Å²	110.9	85%	0.847	65%	0.645	S	S	*	*			trans	-61.9	112.1	170.2	-149.6	-94.6	0	0	0	108.9	F393 P397	F393-Y395 PolarHBondContact O-N 3.02Å; Y395-P397 WeakPolarHBondContact O-CD 3.48Å
396	N	54.5	Low	52	Low	113 Å²	113	115 Å²	115	60%	0.604	66%	0.661	S	S	*	*			trans	-75.9	109.8	173.7	-177.5	-4	0	0	0	109.6	D394 S398	D394-N396 PolarHBondContact O-N 3.33Å; N396-S398 PolarHBondContact O-N 3.12Å; N396-S398 VanDerWaalsContact O-N 3.14Å; N396-S398 WeakPolarHBondContact OD1-CB 3.48Å; N396-S398 PolarHBondContact OD1-N 3.3Å; N396-S398 VanDerWaalsContact OD1-N 3.12Å; N396-S398 PolarHBondContact OD1-OG 3.09Å
397	P	52.8	Low	51.3	Low	122 Å²	122	117.3 Å²	117.3	79%	0.792	67%	0.671	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.7	-2.1	-175.8	31.1	-34.6	0	0	0	113.9	Y395	Y395-P397 WeakPolarHBondContact O-CD 3.48Å
398	S	62.2	Low	50.7	Low	73 Å²	73	118.7 Å²	118.7	51%	0.51	68%	0.676	S	S	.	*	T	Hydrogen-bonded Turn	trans	-74.7	-26.5	-176.2	-40.9	0	0	0	0	113	N396 Q400	N396-S398 PolarHBondContact O-N 3.12Å; N396-S398 VanDerWaalsContact O-N 3.14Å; N396-S398 WeakPolarHBondContact OD1-CB 3.48Å; N396-S398 PolarHBondContact OD1-N 3.3Å; N396-S398 VanDerWaalsContact OD1-N 3.12Å; N396-S398 PolarHBondContact OD1-OG 3.09Å; S398-Q400 PolarHBondContact O-N 3.49Å
399	G	51.1	Low	50.4	Low	76 Å²	76	118.5 Å²	118.5	78%	0.784	68%	0.676	S	S	*	*			trans	53.7	13.2	178.2	0	0	0	0	0	116
400	Q	40.7	Very low	50.1	Low	171 Å²	171	121 Å²	121	80%	0.799	68%	0.678	S	S	*	*			trans	-97.9	113.1	-176.5	-80.2	176.4	-13.5	0	0	109.3	S398	S398-Q400 PolarHBondContact O-N 3.49Å
401	L	45.9	Very low	50.4	Low	128 Å²	128	119.6 Å²	119.6	67%	0.67	67%	0.669	S	S	*	*	P	Polyproline II helix	trans	-67.7	139.7	166.2	-71.7	162.3	0	0	0	109.2
402	P	44.1	Very low	51	Low	90 Å²	90	120.1 Å²	120.1	58%	0.584	67%	0.668	S	S	*	*	P	Polyproline II helix	trans	-58.8	140.8	170.1	-18.7	30.9	0	0	0	110.4	D404	P402-D404 PolarHBondContact O-N 3.17Å
403	A	42.7	Very low	51.6	Low	101 Å²	101	122.5 Å²	122.5	84%	0.835	67%	0.667	S	S	*	*	P	Polyproline II helix	trans	-65.1	119.4	179	0	0	0	0	0	110.6	G405	A403-G405 PolarHBondContact O-N 3.07Å; A403-G405 VanDerWaalsContact O-N 3.17Å
404	D	48.5	Very low	51.8	Low	134 Å²	134	116.5 Å²	116.5	72%	0.717	64%	0.642	S	S	*	*			trans	-52.1	115.3	175.9	-40.1	-24.8	0	0	0	109.2	P402 E406	P402-D404 PolarHBondContact O-N 3.17Å; D404-E406 PolarHBondContact O-N 3.21Å
405	G	45.5	Very low	52.3	Low	68 Å²	68	112.6 Å²	112.6	70%	0.701	62%	0.62	S	S	*	*			trans	-75.4	115.2	-178.4	0	0	0	0	0	111.3	A403 D407	A403-G405 PolarHBondContact O-N 3.07Å; A403-G405 VanDerWaalsContact O-N 3.17Å; G405-D407 PolarHBondContact O-N 3.26Å
406	E	45	Very low	53.4	Low	189 Å²	189	107.6 Å²	107.6	88%	0.883	60%	0.604	S	S	*	*	S	Bend	trans	39.8	59.6	143.8	-60.4	-177.4	177	0	0	117.3	D404	D404-E406 PolarHBondContact O-N 3.21Å
407	D	50.6	Low	53.6	Low	109 Å²	109	105.5 Å²	105.5	58%	0.583	59%	0.591	S	S	*	*			trans	-142.8	11.7	155.7	-85.6	-31.7	0	0	0	112.1	G405 D409 E410 E411	G405-D407 PolarHBondContact O-N 3.26Å; D407-D409 PolarHBondContact O-N 3.26Å; D407-E410 PolarHBondContact O-N 3.28Å; D407-E411 WeakPolarHBondContact O-CB 3.42Å; D407-E411 PolarHBondContact O-N 3.07Å; D407-E411 VanDerWaalsContact O-N 3.17Å
408	E	54.9	Low	53.7	Low	99 Å²	99	101.6 Å²	101.6	46%	0.463	56%	0.562	S	S	.	*	H	α-helix	trans	-59.5	-30.8	-176	-72.8	-169.6	-166.9	0	0	113.8	K412	E408-K412 WeakPolarHBondContact O-CB 3.29Å; E408-K412 WeakPolarHBondContact O-CD 3.42Å; E408-K412 WeakPolarHBondContact O-CG 3.42Å; E408-K412 PolarHBondContact O-N 2.82Å; E408-K412 IonicContact OE2-NZ 2.91Å; E408-K412 PolarHBondContact OE2-NZ 3.4Å
409	D	59	Low	53.6	Low	133 Å²	133	106.2 Å²	106.2	71%	0.711	57%	0.568	S	S	*	*	H	α-helix	trans	-75.6	-42.7	-174.6	-72.3	-28	0	0	0	112	D407 E411 E413	D407-D409 PolarHBondContact O-N 3.26Å; D409-E411 VanDerWaalsContact C-N 3.3Å; D409-E413 PolarHBondContact O-N 2.78Å
410	E	55.4	Low	54	Low	135 Å²	135	109.4 Å²	109.4	63%	0.631	56%	0.557	S	S	*	*	H	α-helix	trans	-66.2	-36.8	172.2	-70.7	-165.9	175.2	0	0	110.8	D407 E413 L414	D407-E410 PolarHBondContact O-N 3.28Å; E410-E413 PolarHBondContact O-N 3.35Å; E410-L414 WeakPolarHBondContact O-CB 3.22Å; E410-L414 WeakPolarHBondContact O-CD1 3.47Å; E410-L414 WeakPolarHBondContact O-CG 3.5Å; E410-L414 PolarHBondContact O-N 3.3Å
411	E	57.8	Low	54.6	Low	73 Å²	73	101.8 Å²	101.8	34%	0.341	52%	0.522	S	S	.	.	H	α-helix	trans	-65.9	-45.9	179.2	-169.6	170	-164.3	0	0	112.4	K208 D407 D409 E413 L414 E415	K208-E411 WeakPolarHBondContact CE-OE1 3.38Å; K208-E411 IonicContact NZ-OE1 2.61Å; K208-E411 PolarHBondContact NZ-OE1 3.09Å; D407-E411 WeakPolarHBondContact O-CB 3.42Å; D407-E411 PolarHBondContact O-N 3.07Å; D407-E411 VanDerWaalsContact O-N 3.17Å; D409-E411 VanDerWaalsContact C-N 3.3Å; E411-E413 VanDerWaalsContact C-N 3.35Å; E411-E413 PolarHBondContact O-N 3.17Å; E411-L414 PolarHBondContact O-N 3.33Å; E411-E415 WeakPolarHBondContact O-CG 3.47Å; E411-E415 PolarHBondContact O-N 3.06Å
412	K	66	Low	55	Low	102 Å²	102	98.2 Å²	98.2	44%	0.443	51%	0.505	S	S	.	.	H	α-helix	trans	-61.5	-41.3	176.1	-75.7	167.5	-167.8	154.5	0	112.1	E408 L414 E415 E416	E408-K412 WeakPolarHBondContact O-CB 3.29Å; E408-K412 WeakPolarHBondContact O-CD 3.42Å; E408-K412 WeakPolarHBondContact O-CG 3.42Å; E408-K412 PolarHBondContact O-N 2.82Å; E408-K412 IonicContact OE2-NZ 2.91Å; E408-K412 PolarHBondContact OE2-NZ 3.4Å; K412-L414 VanDerWaalsContact C-N 3.35Å; K412-E415 PolarHBondContact O-N 3.24Å; K412-E416 PolarHBondContact O-N 3.1Å
413	E	63.8	Low	55.8	Low	121 Å²	121	98.8 Å²	98.8	57%	0.565	50%	0.503	S	S	*	.	H	α-helix	trans	-64.2	-41.5	177.9	-166.9	176.3	175.9	0	0	111.3	D409 E410 E411 E416 Q417	D409-E413 PolarHBondContact O-N 2.78Å; E410-E413 PolarHBondContact O-N 3.35Å; E411-E413 VanDerWaalsContact C-N 3.35Å; E411-E413 PolarHBondContact O-N 3.17Å; E413-E416 PolarHBondContact O-N 3.25Å; E413-Q417 VanDerWaalsContact O-CG 3.29Å; E413-Q417 WeakPolarHBondContact O-CG 3.35Å; E413-Q417 PolarHBondContact O-N 3.25Å
414	L	57.5	Low	56.3	Low	53 Å²	53	98 Å²	98	28%	0.277	48%	0.482	S	S	.	.	H	α-helix	trans	-67.2	-38.3	176.2	-68.8	168.4	0	0	0	112.5	R245 E410 E411 K412 Q417 Q418	R245-L414 VanDerWaalsContact NH1-CB 3.26Å; E410-L414 WeakPolarHBondContact O-CB 3.22Å; E410-L414 WeakPolarHBondContact O-CD1 3.47Å; E410-L414 WeakPolarHBondContact O-CG 3.5Å; E410-L414 PolarHBondContact O-N 3.3Å; E411-L414 PolarHBondContact O-N 3.33Å; K412-L414 VanDerWaalsContact C-N 3.35Å; L414-Q417 PolarHBondContact O-N 3.13Å; L414-Q418 WeakPolarHBondContact O-CB 3.27Å; L414-Q418 PolarHBondContact O-N 3.32Å
415	E	58.3	Low	56.5	Low	59 Å²	59	92 Å²	92	28%	0.276	45%	0.45	S	S	.	.	H	α-helix	trans	-66	-39.2	175.2	-75.4	-172.5	175.6	0	0	112.6	K208 E411 K412 Q418 R419	K208-E415 IonicContact NZ-OE1 3.89Å; K208-E415 PolarHBondContact NZ-OE1 3.39Å; E411-E415 WeakPolarHBondContact O-CG 3.47Å; E411-E415 PolarHBondContact O-N 3.06Å; K412-E415 PolarHBondContact O-N 3.24Å; E415-Q418 WeakPolarHBondContact O-CB 3.16Å; E415-Q418 PolarHBondContact O-N 3.1Å; E415-R419 PolarHBondContact O-N 3.05Å
416	E	65.8	Low	56.7	Low	111 Å²	111	91.3 Å²	91.3	52%	0.519	44%	0.438	S	S	.	.	H	α-helix	trans	-64.7	-43.1	173.3	-79.8	-164.6	-173.8	0	0	111.9	K412 E413 Q418 R419 R420	K412-E416 PolarHBondContact O-N 3.1Å; E413-E416 PolarHBondContact O-N 3.25Å; E416-Q418 VanDerWaalsContact C-N 3.28Å; E416-Q418 PolarHBondContact O-N 3.31Å; E416-R419 PolarHBondContact O-N 2.81Å; E416-R420 WeakPolarHBondContact O-CG 3.38Å; E416-R420 PolarHBondContact O-N 3.14Å; E416-R420 VanDerWaalsContact O-N 3.11Å; E416-R420 IonicContact OE2-NH2 2.72Å; E416-R420 PolarHBondContact OE2-NH2 3.49Å
417	Q	57.5	Low	56.9	Low	69 Å²	69	87 Å²	87	32%	0.322	43%	0.428	S	S	.	.	H	α-helix	trans	-62.2	-38.7	175.2	-70.4	-179.8	29.4	0	0	111	E413 L414 R420 V421	E413-Q417 VanDerWaalsContact O-CG 3.29Å; E413-Q417 WeakPolarHBondContact O-CG 3.35Å; E413-Q417 PolarHBondContact O-N 3.25Å; L414-Q417 PolarHBondContact O-N 3.13Å; Q417-R420 PolarHBondContact O-N 2.96Å; Q417-V421 VanDerWaalsContact O-CG2 3.29Å; Q417-V421 WeakPolarHBondContact O-CG2 3.42Å; Q417-V421 PolarHBondContact O-N 2.74Å
418	Q	56.5	Low	56.8	Low	39 Å²	39	82.4 Å²	82.4	18%	0.182	40%	0.403	C	S	.	.	H	α-helix	trans	-61.9	-48.9	173.8	179.2	-175.9	-3.6	0	0	112.3	L414 E415 E416 R420 V421 V422	L414-Q418 WeakPolarHBondContact O-CB 3.27Å; L414-Q418 PolarHBondContact O-N 3.32Å; E415-Q418 WeakPolarHBondContact O-CB 3.16Å; E415-Q418 PolarHBondContact O-N 3.1Å; E416-Q418 VanDerWaalsContact C-N 3.28Å; E416-Q418 PolarHBondContact O-N 3.31Å; Q418-R420 PolarHBondContact O-N 3.35Å; Q418-V421 PolarHBondContact O-N 3.34Å; Q418-V422 HydrophobicContact CG-CG2 4.21Å; Q418-V422 WeakPolarHBondContact O-CB 3.43Å; Q418-V422 WeakPolarHBondContact O-CG2 3.45Å; Q418-V422 PolarHBondContact O-N 2.92Å
419	R	59	Low	56.3	Low	170 Å²	170	83.6 Å²	83.6	64%	0.642	41%	0.412	S	S	*	.	H	α-helix	trans	-57.3	-41.1	176.6	-72.6	-178.8	-154.2	-105.8	-1.2	111.1	E415 E416 V421 V422 D423	E415-R419 PolarHBondContact O-N 3.05Å; E416-R419 PolarHBondContact O-N 2.81Å; R419-V421 PolarHBondContact O-N 2.77Å; R419-V422 PolarHBondContact O-N 3.06Å; R419-D423 WeakPolarHBondContact O-CB 3.33Å; R419-D423 PolarHBondContact O-N 3.43Å
420	R	58.8	Low	55.6	Low	144 Å²	144	78.6 Å²	78.6	54%	0.543	39%	0.385	S	S	.	.	H	α-helix	trans	-64.1	-39.9	175.3	-66.7	176.3	-163.8	-179.6	10.6	112.6	E416 Q417 Q418 E424	E416-R420 WeakPolarHBondContact O-CG 3.38Å; E416-R420 PolarHBondContact O-N 3.14Å; E416-R420 VanDerWaalsContact O-N 3.11Å; E416-R420 IonicContact OE2-NH2 2.72Å; E416-R420 PolarHBondContact OE2-NH2 3.49Å; Q417-R420 PolarHBondContact O-N 2.96Å; Q418-R420 PolarHBondContact O-N 3.35Å; R420-E424 WeakPolarHBondContact O-CB 3.19Å; R420-E424 WeakPolarHBondContact O-CG 3.45Å; R420-E424 PolarHBondContact O-N 2.89Å
421	V	54.4	Low	54.6	Low	11 Å²	11	73.7 Å²	73.7	7%	0.067	37%	0.371	C	S	.	.	H	α-helix	trans	-70.8	-42	178.1	171.8	0	0	0	0	111.4	L248 Q417 Q418 R419 E424 I425	L248-V421 HydrophobicContact CB-CG1 4.19Å; Q417-V421 VanDerWaalsContact O-CG2 3.29Å; Q417-V421 WeakPolarHBondContact O-CG2 3.42Å; Q417-V421 PolarHBondContact O-N 2.74Å; Q418-V421 PolarHBondContact O-N 3.34Å; R419-V421 PolarHBondContact O-N 2.77Å; V421-E424 PolarHBondContact O-N 3.02Å; V421-I425 HydrophobicContact CG1-CD1 3.73Å; V421-I425 HydrophobicContact CG1-CG1 4.39Å; V421-I425 WeakPolarHBondContact O-CB 3.38Å; V421-I425 WeakPolarHBondContact O-CG1 3.43Å; V421-I425 PolarHBondContact O-N 2.96Å
422	V	55	Low	53.4	Low	53 Å²	53	75.3 Å²	75.3	32%	0.321	39%	0.388	S	S	.	.	H	α-helix	trans	-65.9	-42.9	175.6	174.1	0	0	0	0	110.5	V201 Q418 R419 E424 I425 A426	V201-V422 HydrophobicContact CG1-CG2 4.05Å; V201-V422 HydrophobicContact CG2-CG2 4.34Å; Q418-V422 HydrophobicContact CG-CG2 4.21Å; Q418-V422 WeakPolarHBondContact O-CB 3.43Å; Q418-V422 WeakPolarHBondContact O-CG2 3.45Å; Q418-V422 PolarHBondContact O-N 2.92Å; R419-V422 PolarHBondContact O-N 3.06Å; V422-E424 VanDerWaalsContact C-N 3.35Å; V422-I425 CarbonylContact O-C 3.53Å; V422-I425 PolarHBondContact O-N 2.94Å; V422-A426 WeakPolarHBondContact O-CB 3.39Å; V422-A426 PolarHBondContact O-N 3.44Å
423	D	59.8	Low	51.9	Low	101 Å²	101	74.5 Å²	74.5	54%	0.54	40%	0.395	S	S	.	.	H	α-helix	trans	-64.3	-38.7	174.5	-76.1	-17.7	0	0	0	111	R419 A426 C427	R419-D423 WeakPolarHBondContact O-CB 3.33Å; R419-D423 PolarHBondContact O-N 3.43Å; D423-A426 CarbonylContact O-C 3.55Å; D423-A426 PolarHBondContact O-N 3.49Å; D423-C427 WeakPolarHBondContact O-CA 3.44Å; D423-C427 WeakPolarHBondContact O-CB 3.15Å; D423-C427 PolarHBondContact O-N 3.4Å; D423-C427 PolarHBondContact O-SG 2.9Å
424	E	52.6	Low	50.6	Low	85 Å²	85	76.9 Å²	76.9	40%	0.397	41%	0.412	S	S	.	.	H	α-helix	trans	-68.4	-39.1	173.6	-82.2	-177.3	-174.4	0	0	112.6	R252 R420 V421 V422 A426 C427 I428	R252-E424 IonicContact CZ-OE1 3.11Å; R252-E424 IonicContact CZ-OE2 3.34Å; R252-E424 VanDerWaalsContact CZ-OE2 3.28Å; R252-E424 IonicContact NE-OE1 2.66Å; R252-E424 IonicContact NE-OE2 2.77Å; R252-E424 PolarHBondContact NE-OE2 3.42Å; R252-E424 IonicContact NH2-OE1 2.69Å; R252-E424 PolarHBondContact NH2-OE1 3.22Å; R252-E424 IonicContact NH2-OE2 3.04Å; R252-E424 PolarHBondContact NH2-OE2 2.91Å; R252-E424 VanDerWaalsContact NH2-OE2 3.17Å; R420-E424 WeakPolarHBondContact O-CB 3.19Å; R420-E424 WeakPolarHBondContact O-CG 3.45Å; R420-E424 PolarHBondContact O-N 2.89Å; V421-E424 PolarHBondContact O-N 3.02Å; V422-E424 VanDerWaalsContact C-N 3.35Å; E424-A426 VanDerWaalsContact C-N 3.3Å; E424-C427 CarbonylContact O-C 3.5Å; E424-C427 PolarHBondContact O-N 3.07Å; E424-I428 VanDerWaalsContact O-CG1 3.24Å; E424-I428 WeakPolarHBondContact O-CG1 3.22Å; E424-I428 PolarHBondContact O-N 3.28Å
425	I	53.5	Low	49.5	Very low	8 Å²	8	77.3 Å²	77.3	4%	0.041	43%	0.429	C	S	.	.	H	α-helix	trans	-67.3	-31.5	173.5	-69.9	169.3	0	0	0	111.1	L197 K198 L248 I255 V421 V422 I428	L197-I425 HydrophobicContact CB-CD1 4.45Å; K198-I425 HydrophobicContact CD-CG2 4.47Å; K198-I425 HydrophobicContact CG-CG2 3.97Å; L248-I425 HydrophobicContact CD2-CD1 4.38Å; I255-I425 HydrophobicContact CD1-CD1 4.43Å; I255-I425 HydrophobicContact CD1-CG1 4.18Å; V421-I425 HydrophobicContact CG1-CD1 3.73Å; V421-I425 HydrophobicContact CG1-CG1 4.39Å; V421-I425 WeakPolarHBondContact O-CB 3.38Å; V421-I425 WeakPolarHBondContact O-CG1 3.43Å; V421-I425 PolarHBondContact O-N 2.96Å; V422-I425 CarbonylContact O-C 3.53Å; V422-I425 PolarHBondContact O-N 2.94Å; I425-I428 HydrophobicContact CB-CD1 4.46Å; I425-I428 HydrophobicContact CG2-CD1 4.43Å; I425-I428 WeakPolarHBondContact O-CG1 3.37Å
426	A	50.5	Low	48.3	Very low	54 Å²	54	82.8 Å²	82.8	45%	0.446	45%	0.454	S	S	.	.	H	α-helix	trans	-78.8	-33.4	173.8	0	0	0	0	0	112	V422 D423 E424 I428 D429	V422-A426 WeakPolarHBondContact O-CB 3.39Å; V422-A426 PolarHBondContact O-N 3.44Å; D423-A426 CarbonylContact O-C 3.55Å; D423-A426 PolarHBondContact O-N 3.49Å; E424-A426 VanDerWaalsContact C-N 3.3Å; A426-I428 CarbonylContact O-C 3.55Å; A426-I428 PolarHBondContact O-N 3.49Å; A426-D429 PolarHBondContact O-N 3.34Å
427	C	48.4	Very low	46.6	Very low	99 Å²	99	87.3 Å²	87.3	67%	0.669	47%	0.472	S	S	*	.	H	α-helix	trans	-73.9	-9.2	171.3	-72	0	0	0	0	112.5	D423 E424 D429	D423-C427 WeakPolarHBondContact O-CA 3.44Å; D423-C427 WeakPolarHBondContact O-CB 3.15Å; D423-C427 PolarHBondContact O-N 3.4Å; D423-C427 PolarHBondContact O-SG 2.9Å; E424-C427 CarbonylContact O-C 3.5Å; E424-C427 PolarHBondContact O-N 3.07Å; C427-D429 PolarHBondContact O-N 2.98Å
428	I	48.3	Very low	45.1	Very low	11 Å²	11	93 Å²	93	6%	0.056	50%	0.499	C	S	.	.			trans	-69.3	70.4	149.1	-24.2	166.7	0	0	0	106.7	I255 E424 I425 A426 L430	I255-I428 HydrophobicContact CG2-CD1 3.3Å; I255-I428 HydrophobicContact CG2-CG1 4.04Å; E424-I428 VanDerWaalsContact O-CG1 3.24Å; E424-I428 WeakPolarHBondContact O-CG1 3.22Å; E424-I428 PolarHBondContact O-N 3.28Å; I425-I428 HydrophobicContact CB-CD1 4.46Å; I425-I428 HydrophobicContact CG2-CD1 4.43Å; I425-I428 WeakPolarHBondContact O-CG1 3.37Å; A426-I428 CarbonylContact O-C 3.55Å; A426-I428 PolarHBondContact O-N 3.49Å; I428-L430 HydrophobicContact CB-CD1 4.28Å; I428-L430 HydrophobicContact CB-CD2 4.5Å; I428-L430 HydrophobicContact CB-CG 4.04Å; I428-L430 HydrophobicContact CG2-CD1 3.82Å; I428-L430 HydrophobicContact CG2-CD2 3.34Å; I428-L430 HydrophobicContact CG2-CG 3.38Å; I428-L430 PolarHBondContact O-N 3.02Å
429	D	44.3	Very low	43.7	Very low	124 Å²	124	99.9 Å²	99.9	66%	0.663	53%	0.531	S	S	*	.			trans	-63.8	85.5	158.1	-175.1	2.2	0	0	0	105.5	A426 C427 G431	A426-D429 PolarHBondContact O-N 3.34Å; C427-D429 PolarHBondContact O-N 2.98Å; D429-G431 PolarHBondContact O-N 3.27Å; D429-G431 PolarHBondContact OD1-N 3.41Å; D429-G431 VanDerWaalsContact OD1-N 3.13Å
430	L	44.3	Very low	42.2	Very low	29 Å²	29	97.3 Å²	97.3	15%	0.152	53%	0.534	C	S	.	.			trans	-74.5	16.8	176	-68.3	163.5	0	0	0	110.9	K187 M190 D191 I428	K187-L430 WeakPolarHBondContact CE-O 3.46Å; K187-L430 PolarHBondContact NZ-O 3.2Å; M190-L430 HydrophobicContact CB-CD1 4.44Å; M190-L430 HydrophobicContact CB-CD2 4.21Å; D191-L430 HydrophobicContact CB-CD1 4.45Å; D191-L430 WeakPolarHBondContact OD1-CB 3.49Å; D191-L430 WeakPolarHBondContact OD1-CD1 3.47Å; D191-L430 WeakPolarHBondContact OD1-CG 3.47Å; I428-L430 HydrophobicContact CB-CD1 4.28Å; I428-L430 HydrophobicContact CB-CD2 4.5Å; I428-L430 HydrophobicContact CB-CG 4.04Å; I428-L430 HydrophobicContact CG2-CD1 3.82Å; I428-L430 HydrophobicContact CG2-CD2 3.34Å; I428-L430 HydrophobicContact CG2-CG 3.38Å; I428-L430 PolarHBondContact O-N 3.02Å
431	G	34.9	Very low	40.7	Very low	31 Å²	31	97.3 Å²	97.3	32%	0.32	55%	0.55	S	S	.	.			trans	69.7	169.2	-177.3	0	0	0	0	0	111.8	D429 S433	D429-G431 PolarHBondContact O-N 3.27Å; D429-G431 PolarHBondContact OD1-N 3.41Å; D429-G431 VanDerWaalsContact OD1-N 3.13Å; G431-S433 PolarHBondContact O-N 3.02Å
432	P	32.4	Very low	39.5	Very low	108 Å²	108	102.6 Å²	102.6	70%	0.701	58%	0.582	S	S	*	*			trans	-58	133.5	179.7	23.8	-31.6	0	0	0	109.3	D434	P432-D434 PolarHBondContact O-N 3.43Å; P432-D434 VanDerWaalsContact O-N 3.12Å
433	S	34.9	Very low	38.2	Very low	84 Å²	84	105.2 Å²	105.2	59%	0.587	60%	0.603	S	S	*	*			trans	-54.5	118.4	156.7	52.3	0	0	0	0	106.2	G431 G435	G431-S433 PolarHBondContact O-N 3.02Å; S433-G435 PolarHBondContact O-N 3.36Å
434	D	36	Very low	36.7	Very low	172 Å²	172	107.8 Å²	107.8	92%	0.92	62%	0.616	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.2	88.8	161.8	-77.2	-37.9	0	0	0	106.1	P432	P432-D434 PolarHBondContact O-N 3.43Å; P432-D434 VanDerWaalsContact O-N 3.12Å
435	G	34.7	Very low	35.7	Very low	62 Å²	62	112.1 Å²	112.1	64%	0.639	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-175	-26.6	-170.5	0	0	0	0	0	115.5	S433	S433-G435 PolarHBondContact O-N 3.36Å
436	E	32.1	Very low	34.6	Very low	174 Å²	174	116.9 Å²	116.9	81%	0.813	67%	0.671	S	S	*	*	S	Bend	trans	-114.5	16.4	-178.7	-76.1	-173.4	172.6	0	0	115.4
437	K	29.6	Very low	33.5	Very low	205 Å²	205	120.4 Å²	120.4	89%	0.891	69%	0.687	S	S	*	*	S	Bend	trans	-126.9	54.7	164.8	-70.3	-169.1	-179	-179.4	0	112.5
438	Q	27	Very low	33	Very low	190 Å²	190	128.5 Å²	128.5	89%	0.888	71%	0.711	S	S	*	*			trans	-140.2	46.9	154.4	-97.1	178.2	2.3	0	0	109.9	T440	Q438-T440 VanDerWaalsContact C-N 3.31Å; Q438-T440 PolarHBondContact O-N 3.34Å; Q438-T440 VanDerWaalsContact O-N 3.12Å
439	E	27.9	Very low	32.2	Very low	182 Å²	182	134.4 Å²	134.4	85%	0.85	74%	0.744	S	S	*	*			trans	-73.3	95.2	152.8	-89.3	-173.5	153.7	0	0	108.3
440	T	26.6	Very low	31.6	Very low	116 Å²	116	134.9 Å²	134.9	71%	0.712	75%	0.748	S	S	*	*			trans	47.8	79.2	132	-37.1	0	0	0	0	116.6	Q438	Q438-T440 VanDerWaalsContact C-N 3.31Å; Q438-T440 PolarHBondContact O-N 3.34Å; Q438-T440 VanDerWaalsContact O-N 3.12Å
441	V	28	Very low	30.9	Very low	144 Å²	144	140.8 Å²	140.8	87%	0.873	78%	0.781	S	S	*	*			trans	-106	64.5	149.7	-171	0	0	0	0	108.2
442	V	28.3	Very low	30.6	Very low	123 Å²	123	147.3 Å²	147.3	75%	0.745	81%	0.808	S	S	*	*			trans	-144.9	79	162.2	-163.4	0	0	0	0	108.4
443	S	27	Very low	30.5	Very low	108 Å²	108	149.8 Å²	149.8	76%	0.755	82%	0.815	S	S	*	*			trans	179.2	86.9	147.5	-84.2	0	0	0	0	108.6
444	N	28.7	Very low	30.2	Very low	154 Å²	154	154.1 Å²	154.1	82%	0.824	83%	0.83	S	S	*	*			trans	-167.4	55.5	150.6	-90.8	-17.2	0	0	0	108.1	V446	N444-V446 VanDerWaalsContact C-N 3.33Å
445	L	31.9	Very low	29.8	Very low	176 Å²	176	152.9 Å²	152.9	92%	0.921	82%	0.824	S	S	*	*			trans	-97.2	80.1	151.9	-94.2	154.7	0	0	0	105.4	T447	L445-T447 PolarHBondContact O-N 3.01Å
446	V	30.5	Very low	29.5	Very low	108 Å²	108	159.8 Å²	159.8	66%	0.655	84%	0.838	S	S	*	*			trans	-67	116.8	169.4	172.9	0	0	0	0	106.9	N444 F448	N444-V446 VanDerWaalsContact C-N 3.33Å; V446-F448 PolarHBondContact O-N 3.36Å
447	T	26.7	Very low	29.2	Very low	128 Å²	128	158.7 Å²	158.7	79%	0.785	84%	0.84	S	S	*	*			trans	-51.9	123.6	160.1	14.4	0	0	0	0	110.9	L445	L445-T447 PolarHBondContact O-N 3.01Å
448	F	38.7	Very low	29.2	Very low	270 Å²	270	154.5 Å²	154.5	100%	1.184	84%	0.836	S	S	*	*			trans	-138.7	0	134.4	-95.4	-74.8	0	0	0	108.3	V446	V446-F448 PolarHBondContact O-N 3.36Å

Retrieved 448 of 448 residues in 931.2 ms (Link to these results)

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