A0A077Z7D2_TRITR Loading...

Uncharacterized protein

AlphaFold DB , UniProt , Accession A0A077Z7D2, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 709 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M51.3Low58.2Low241 Ų241131.9 Ų131.9100%1.18762%0.622SS**  0153.10-72.5178173.600109
2L56.1Low58.2Low84 Ų84129 Ų12944%0.4461%0.613SS.*  trans-70.4143.4171-139.474.2000109.7L6 Q7 V10L2-L6 HydrophobicContact CD1-CD2 4.19Å; L2-L6 HydrophobicContact CD2-CB 4.08Å; L2-L6 HydrophobicContact CD2-CD2 4.03Å; L2-L6 HydrophobicContact CD2-CG 4.2Å; L2-L6 HydrophobicContact CG-CB 4.17Å; L2-L6 HydrophobicContact CG-CD2 3.89Å; L2-L6 HydrophobicContact CG-CG 4.44Å; L2-Q7 HydrophobicContact CB-CG 4.24Å; L2-Q7 HydrophobicContact CD2-CG 4.43Å; L2-V10 HydrophobicContact CD2-CG2 4.31Å
3P66.9Low58.4Low87 Ų87127.2 Ų127.257%0.56561%0.607SS**  trans-56.7141.5173.3-25.434.9000111.3D5 L6 Q7P3-D5 PolarHBondContact O-N 3.23Å; P3-D5 VanDerWaalsContact O-N 3.12Å; P3-L6 HydrophobicContact CB-CB 4.28Å; P3-L6 WeakPolarHBondContact O-CA 3.4Å; P3-L6 WeakPolarHBondContact O-CB 3.38Å; P3-L6 PolarHBondContact O-N 2.98Å; P3-Q7 PolarHBondContact O-N 3.13Å
4R65.9Low58.5Low205 Ų205121.8 Ų121.877%0.77460%0.595SS**Hα-helixtrans-54.3-37.4-173.7-74-176.4176.1179.3-0.6112.7Q7 K8R4-Q7 VanDerWaalsContact O-CB 3.29Å; R4-Q7 WeakPolarHBondContact O-CB 3.39Å; R4-Q7 PolarHBondContact O-N 3.04Å; R4-K8 WeakPolarHBondContact O-CG 3.44Å; R4-K8 PolarHBondContact O-N 3.47Å
5D64.9Low60Low96 Ų96116.5 Ų116.551%0.51357%0.574SS.*Hα-helixtrans-79.8-26.3-179.9-52.6-64.5000113.2P3 K8 R9P3-D5 PolarHBondContact O-N 3.23Å; P3-D5 VanDerWaalsContact O-N 3.12Å; D5-K8 PolarHBondContact O-N 3.27Å; D5-K8 IonicContact OD1-NZ 3.55Å; D5-K8 PolarHBondContact OD1-NZ 3.45Å; D5-R9 WeakPolarHBondContact O-CB 3.45Å; D5-R9 WeakPolarHBondContact O-CG 3.26Å; D5-R9 PolarHBondContact O-N 3.27Å
6L59.6Low61.6Low88 Ų88113.1 Ų113.146%0.46156%0.555SS.*Hα-helixtrans-69.9-37.3166.8-147.774.7000110.4L2 P3 R9 V10L2-L6 HydrophobicContact CD1-CD2 4.19Å; L2-L6 HydrophobicContact CD2-CB 4.08Å; L2-L6 HydrophobicContact CD2-CD2 4.03Å; L2-L6 HydrophobicContact CD2-CG 4.2Å; L2-L6 HydrophobicContact CG-CB 4.17Å; L2-L6 HydrophobicContact CG-CD2 3.89Å; L2-L6 HydrophobicContact CG-CG 4.44Å; P3-L6 HydrophobicContact CB-CB 4.28Å; P3-L6 WeakPolarHBondContact O-CA 3.4Å; P3-L6 WeakPolarHBondContact O-CB 3.38Å; P3-L6 PolarHBondContact O-N 2.98Å; L6-R9 PolarHBondContact O-N 3.11Å; L6-V10 WeakPolarHBondContact O-CB 3.29Å; L6-V10 VanDerWaalsContact O-CG2 3.26Å; L6-V10 WeakPolarHBondContact O-CG2 3.4Å; L6-V10 PolarHBondContact O-N 3.44Å
7Q58.3Low63Low110 Ų110109.6 Ų109.651%0.51455%0.548SS..Hα-helixtrans-60.7-45.7170.7-114.5178.12.100112L2 P3 R4 K11L2-Q7 HydrophobicContact CB-CG 4.24Å; L2-Q7 HydrophobicContact CD2-CG 4.43Å; P3-Q7 PolarHBondContact O-N 3.13Å; R4-Q7 VanDerWaalsContact O-CB 3.29Å; R4-Q7 WeakPolarHBondContact O-CB 3.39Å; R4-Q7 PolarHBondContact O-N 3.04Å; Q7-K11 VanDerWaalsContact O-CB 3.25Å; Q7-K11 WeakPolarHBondContact O-CB 3.05Å; Q7-K11 PolarHBondContact O-N 2.91Å
8K56.8Low64.4Low124 Ų124112.3 Ų112.354%0.53955%0.551SS.*Hα-helixtrans-60.7-48.2173.2-70.9173.3-169.9159.20111.6R4 D5 K11 N12R4-K8 WeakPolarHBondContact O-CG 3.44Å; R4-K8 PolarHBondContact O-N 3.47Å; D5-K8 PolarHBondContact O-N 3.27Å; D5-K8 IonicContact OD1-NZ 3.55Å; D5-K8 PolarHBondContact OD1-NZ 3.45Å; K8-K11 PolarHBondContact O-N 3.43Å; K8-N12 WeakPolarHBondContact O-CB 3.47Å; K8-N12 VanDerWaalsContact O-CG 3.32Å; K8-N12 PolarHBondContact O-N 3.36Å; K8-N12 PolarHBondContact O-OD1 3.39Å
9R52.7Low65.8Low170 Ų170107.4 Ų107.464%0.64253%0.527SS*.Hα-helixtrans-59-49.6177.4-75.5-179.6-173.6-117.44.8111.2D5 L6 K11 N12 I13D5-R9 WeakPolarHBondContact O-CB 3.45Å; D5-R9 WeakPolarHBondContact O-CG 3.26Å; D5-R9 PolarHBondContact O-N 3.27Å; L6-R9 PolarHBondContact O-N 3.11Å; R9-K11 PolarHBondContact O-N 3.2Å; R9-N12 CarbonylContact O-C 3.55Å; R9-N12 PolarHBondContact O-N 3.21Å; R9-N12 VanDerWaalsContact O-N 3.12Å; R9-I13 HydrophobicContact CB-CD1 4.4Å; R9-I13 WeakPolarHBondContact O-CB 3.31Å; R9-I13 WeakPolarHBondContact O-CD1 3.25Å; R9-I13 WeakPolarHBondContact O-CG1 3.41Å; R9-I13 PolarHBondContact O-N 2.85Å
10V51.3Low67Low79 Ų79105.5 Ų105.548%0.47952%0.518SS..Hα-helixtrans-60-43.5176.8169.80000111.7L2 L6 N12 I13 A14L2-V10 HydrophobicContact CD2-CG2 4.31Å; L6-V10 WeakPolarHBondContact O-CB 3.29Å; L6-V10 VanDerWaalsContact O-CG2 3.26Å; L6-V10 WeakPolarHBondContact O-CG2 3.4Å; L6-V10 PolarHBondContact O-N 3.44Å; V10-N12 PolarHBondContact O-N 3.43Å; V10-I13 PolarHBondContact O-N 2.94Å; V10-A14 WeakPolarHBondContact O-CB 3.27Å; V10-A14 PolarHBondContact O-N 2.97Å
11K56.6Low68.3Low167 Ų167104.2 Ų104.273%0.72651%0.51SS*.Hα-helixtrans-64.3-27.3177-166.9175.2-178-177.90112.9Q7 K8 R9 P15Q7-K11 VanDerWaalsContact O-CB 3.25Å; Q7-K11 WeakPolarHBondContact O-CB 3.05Å; Q7-K11 PolarHBondContact O-N 2.91Å; K8-K11 PolarHBondContact O-N 3.43Å; R9-K11 PolarHBondContact O-N 3.2Å; K11-P15 WeakPolarHBondContact O-CD 3.46Å
12N57.9Low70.2Confident97 Ų9793.1 Ų93.152%0.51946%0.455SS..Hα-helixtrans-89.3-25.6175.3-68.31.5000113.5K8 R9 V10 P15K8-N12 WeakPolarHBondContact O-CB 3.47Å; K8-N12 VanDerWaalsContact O-CG 3.32Å; K8-N12 PolarHBondContact O-N 3.36Å; K8-N12 PolarHBondContact O-OD1 3.39Å; R9-N12 CarbonylContact O-C 3.55Å; R9-N12 PolarHBondContact O-N 3.21Å; R9-N12 VanDerWaalsContact O-N 3.12Å; V10-N12 PolarHBondContact O-N 3.43Å; N12-P15 WeakPolarHBondContact O-CD 3.39Å; N12-P15 WeakPolarHBondContact O-CG 3.38Å
13I60.9Low72Confident105 Ų10589.1 Ų89.154%0.53844%0.435SS..Hα-helixtrans-75-42.6174.7-70.7161.3000110.8R9 V10 K16 A17R9-I13 HydrophobicContact CB-CD1 4.4Å; R9-I13 WeakPolarHBondContact O-CB 3.31Å; R9-I13 WeakPolarHBondContact O-CD1 3.25Å; R9-I13 WeakPolarHBondContact O-CG1 3.41Å; R9-I13 PolarHBondContact O-N 2.85Å; V10-I13 PolarHBondContact O-N 2.94Å; I13-K16 PolarHBondContact O-N 3.28Å; I13-K16 VanDerWaalsContact O-N 3.1Å; I13-A17 PolarHBondContact O-N 3.3Å
14A60.1Low73.3Confident52 Ų5287.8 Ų87.843%0.4343%0.425SS..Hα-helixtrans-51.1-46.318000000115V10 R18V10-A14 WeakPolarHBondContact O-CB 3.27Å; V10-A14 PolarHBondContact O-N 2.97Å; A14-R18 WeakPolarHBondContact O-CB 3.2Å; A14-R18 PolarHBondContact O-N 3.03Å; A14-R18 VanDerWaalsContact O-N 3.11Å
15P81.2Confident74.7Confident43 Ų4378.6 Ų78.628%0.27939%0.391SS..Hα-helixtrans-69.5-38.6175.226.4-34.8000112.9K11 N12 R18 I19 L140K11-P15 WeakPolarHBondContact O-CD 3.46Å; N12-P15 WeakPolarHBondContact O-CD 3.39Å; N12-P15 WeakPolarHBondContact O-CG 3.38Å; P15-R18 PolarHBondContact O-N 3.37Å; P15-I19 VanDerWaalsContact O-CG1 3.31Å; P15-I19 WeakPolarHBondContact O-CG1 3.24Å; P15-I19 PolarHBondContact O-N 3.49Å; P15-L140 HydrophobicContact CB-CD1 4Å; P15-L140 HydrophobicContact CG-CD1 4.22Å; P15-L140 HydrophobicContact CG-CD2 4.42Å
16K84.8Confident76.1Confident62 Ų6274 Ų7427%0.2737%0.367SS..Hα-helixtrans-60.1-49.9176.2-70-168.7-174.1-162.50111.5I13 R18 I19 I20 F137 L140 S141I13-K16 PolarHBondContact O-N 3.28Å; I13-K16 VanDerWaalsContact O-N 3.1Å; K16-R18 VanDerWaalsContact C-N 3.29Å; K16-R18 PolarHBondContact O-N 3.27Å; K16-I19 PolarHBondContact O-N 2.89Å; K16-I20 WeakPolarHBondContact O-CG1 3.15Å; K16-I20 PolarHBondContact O-N 3.07Å; K16-F137 HydrophobicContact CB-CE2 4.14Å; K16-F137 HydrophobicContact CD-CE2 4.22Å; K16-F137 HydrophobicContact CG-CD2 4.48Å; K16-F137 HydrophobicContact CG-CE2 4.17Å; K16-L140 VanDerWaalsContact CE-C 3.47Å; K16-L140 WeakPolarHBondContact CE-O 3.45Å; K16-L140 HydrophobicContact CG-CB 4.06Å; K16-L140 HydrophobicContact CG-CD1 4.27Å; K16-L140 PolarHBondContact NZ-O 3.32Å; K16-S141 WeakPolarHBondContact CE-OG 3.39Å; K16-S141 PolarHBondContact NZ-OG 3.09Å
17A86Confident77.8Confident54 Ų5469.9 Ų69.945%0.44635%0.345SS..Hα-helixtrans-60.2-39.1177.700000111.8I13 I20 K21I13-A17 PolarHBondContact O-N 3.3Å; A17-I20 PolarHBondContact O-N 3.48Å; A17-K21 WeakPolarHBondContact O-CB 3.37Å; A17-K21 PolarHBondContact O-N 3.29Å
18R88.8Confident79.5Confident158 Ų15866.2 Ų66.260%0.59633%0.331SS*.Hα-helixtrans-65.7-40.5175.8-168.9-178.8-62-173.5-0.7112.8A14 P15 K16 N22 D245A14-R18 WeakPolarHBondContact O-CB 3.2Å; A14-R18 PolarHBondContact O-N 3.03Å; A14-R18 VanDerWaalsContact O-N 3.11Å; P15-R18 PolarHBondContact O-N 3.37Å; K16-R18 VanDerWaalsContact C-N 3.29Å; K16-R18 PolarHBondContact O-N 3.27Å; R18-N22 PolarHBondContact O-N 2.89Å; R18-N22 PolarHBondContact O-ND2 3.21Å; R18-D245 VanDerWaalsContact CD-OD2 3.29Å; R18-D245 WeakPolarHBondContact CD-OD2 3.22Å; R18-D245 WeakPolarHBondContact CG-OD2 3.41Å
19I89.7Confident81.3Confident19 Ų1960.3 Ų60.310%0.09731%0.306CS..Hα-helixtrans-63.1-48.8175.6-66.7162.2000110.1P15 K16 K21 N22 V23 R136 F137 L140 F152P15-I19 VanDerWaalsContact O-CG1 3.31Å; P15-I19 WeakPolarHBondContact O-CG1 3.24Å; P15-I19 PolarHBondContact O-N 3.49Å; K16-I19 PolarHBondContact O-N 2.89Å; I19-K21 PolarHBondContact O-N 2.96Å; I19-N22 PolarHBondContact O-N 3.04Å; I19-N22 VanDerWaalsContact O-N 3.16Å; I19-V23 PolarHBondContact O-N 3.03Å; I19-R136 HydrophobicContact CD1-CB 3.87Å; I19-F137 HydrophobicContact CG2-CB 4.34Å; I19-L140 HydrophobicContact CD1-CD1 3.7Å; I19-F152 HydrophobicContact CG2-CE2 3.72Å; I19-F152 HydrophobicContact CG2-CZ 3.9Å
20I91Very high83.2Confident69 Ų6952.2 Ų52.235%0.35428%0.275SS..Hα-helixtrans-61.3-44.8178.3-64.8167.9000110.9K16 A17 N22 V23 V24 F137K16-I20 WeakPolarHBondContact O-CG1 3.15Å; K16-I20 PolarHBondContact O-N 3.07Å; A17-I20 PolarHBondContact O-N 3.48Å; I20-N22 VanDerWaalsContact C-N 3.3Å; I20-N22 PolarHBondContact O-N 3.47Å; I20-V23 PolarHBondContact O-N 3.03Å; I20-V24 HydrophobicContact CG2-CG2 4.34Å; I20-V24 WeakPolarHBondContact O-CG2 3.47Å; I20-V24 PolarHBondContact O-N 2.96Å; I20-F137 HydrophobicContact CD1-CE2 3.85Å; I20-F137 HydrophobicContact CD1-CZ 4.39Å; I20-F137 HydrophobicContact CG1-CE2 4.12Å
21K93.5Very high85.3Confident78 Ų7849.9 Ų49.934%0.33926%0.259SS..Hα-helixtrans-50-50.6172.6-178.7-148.662151.20110.9A17 I19 V23 V24 V25 L243 D245A17-K21 WeakPolarHBondContact O-CB 3.37Å; A17-K21 PolarHBondContact O-N 3.29Å; I19-K21 PolarHBondContact O-N 2.96Å; K21-V23 PolarHBondContact O-N 3.17Å; K21-V24 PolarHBondContact O-N 3.16Å; K21-V25 HydrophobicContact CG-CG2 4.29Å; K21-V25 WeakPolarHBondContact O-CB 3.29Å; K21-V25 WeakPolarHBondContact O-CG2 3.44Å; K21-V25 PolarHBondContact O-N 2.96Å; K21-L243 PolarHBondContact NZ-O 3.49Å; K21-D245 IonicContact NZ-OD1 2.75Å; K21-D245 PolarHBondContact NZ-OD1 3.13Å; K21-D245 IonicContact NZ-OD2 2.91Å; K21-D245 PolarHBondContact NZ-OD2 2.87Å
22N92.3Very high87.1Confident8 Ų843.8 Ų43.84%0.04323%0.233CC..Hα-helixtrans-66.7-36.8-177.2-72.7-38.6000113.2R18 I19 I20 L26 Y129 L244 D245R18-N22 PolarHBondContact O-N 2.89Å; R18-N22 PolarHBondContact O-ND2 3.21Å; I19-N22 PolarHBondContact O-N 3.04Å; I19-N22 VanDerWaalsContact O-N 3.16Å; I20-N22 VanDerWaalsContact C-N 3.3Å; I20-N22 PolarHBondContact O-N 3.47Å; N22-L26 VanDerWaalsContact O-CB 3.32Å; N22-L26 WeakPolarHBondContact O-CB 3.37Å; N22-L26 PolarHBondContact O-N 2.96Å; N22-Y129 HydrophobicContact CB-CE1 4.05Å; N22-Y129 WeakPolarHBondContact CB-OH 2.98Å; N22-L244 HydrophobicContact CB-CD1 4.16Å; N22-L244 WeakPolarHBondContact O-CD1 3.46Å; N22-D245 PolarHBondContact ND2-OD2 2.96Å; N22-D245 PolarHBondContact OD1-N 3.03Å; N22-D245 PolarHBondContact OD1-OD2 3.07Å
23V93.2Very high88.8Confident1 Ų139.2 Ų39.21%0.00621%0.209CC..Hα-helixtrans-65.7-43.2174.2173.90000111.3I19 I20 K21 L26 G27 L130 F152 I155I19-V23 PolarHBondContact O-N 3.03Å; I20-V23 PolarHBondContact O-N 3.03Å; K21-V23 PolarHBondContact O-N 3.17Å; V23-L26 PolarHBondContact O-N 3.32Å; V23-G27 PolarHBondContact O-N 3.14Å; V23-L130 HydrophobicContact CG1-CD1 3.84Å; V23-L130 HydrophobicContact CG2-CD1 4.26Å; V23-F152 HydrophobicContact CG1-CB 4.18Å; V23-F152 HydrophobicContact CG1-CD1 4.48Å; V23-F152 HydrophobicContact CG1-CG 4.22Å; V23-F152 HydrophobicContact CG2-CD2 3.72Å; V23-F152 HydrophobicContact CG2-CE2 3.9Å; V23-F152 HydrophobicContact CG2-CG 4.09Å; V23-F152 HydrophobicContact CG2-CZ 4.42Å; V23-I155 HydrophobicContact CG1-CB 4.49Å; V23-I155 HydrophobicContact CG1-CG2 4.21Å
24V94.8Very high90.3Very high58 Ų5834.4 Ų34.435%0.35218%0.184SC..Hα-helixtrans-65.2-44.1176173.40000111.2I20 K21 L26 G27 C28 I155 L159I20-V24 HydrophobicContact CG2-CG2 4.34Å; I20-V24 WeakPolarHBondContact O-CG2 3.47Å; I20-V24 PolarHBondContact O-N 2.96Å; K21-V24 PolarHBondContact O-N 3.16Å; V24-L26 PolarHBondContact O-N 3.3Å; V24-G27 PolarHBondContact O-N 3.49Å; V24-C28 WeakPolarHBondContact O-CB 3.48Å; V24-C28 PolarHBondContact O-N 2.87Å; V24-C28 PolarHBondContact O-SG 2.75Å; V24-C28 VanDerWaalsContact O-SG 3.33Å; V24-I155 HydrophobicContact CG2-CG2 4.15Å; V24-L159 HydrophobicContact CG1-CD1 4.35Å
25V94.8Very high91.8Very high13 Ų1332 Ų328%0.07916%0.164CC..Hα-helixtrans-61.1-42.5176.11670000111.8K21 C28 S29 L243 L244K21-V25 HydrophobicContact CG-CG2 4.29Å; K21-V25 WeakPolarHBondContact O-CB 3.29Å; K21-V25 WeakPolarHBondContact O-CG2 3.44Å; K21-V25 PolarHBondContact O-N 2.96Å; V25-C28 PolarHBondContact O-N 3.48Å; V25-S29 WeakPolarHBondContact O-CB 3.44Å; V25-S29 PolarHBondContact O-N 3.16Å; V25-L243 HydrophobicContact CB-CB 4.37Å; V25-L243 HydrophobicContact CG1-CB 3.69Å; V25-L243 HydrophobicContact CG2-CB 3.68Å; V25-L243 HydrophobicContact CG2-CD1 4.22Å; V25-L244 HydrophobicContact CB-CD1 4.4Å; V25-L244 HydrophobicContact CG1-CB 3.93Å; V25-L244 HydrophobicContact CG1-CD1 4.08Å
26L93.9Very high92.2Very high0 Ų030 Ų300%015%0.151CC..Hα-helixtrans-61.7-45.1175.2178.860.3000111.3N22 V23 V24 S29 S30 L86 L126 Y129 L244N22-L26 VanDerWaalsContact O-CB 3.32Å; N22-L26 WeakPolarHBondContact O-CB 3.37Å; N22-L26 PolarHBondContact O-N 2.96Å; V23-L26 PolarHBondContact O-N 3.32Å; V24-L26 PolarHBondContact O-N 3.3Å; L26-S29 PolarHBondContact O-N 3.25Å; L26-S30 WeakPolarHBondContact O-CB 3.25Å; L26-S30 PolarHBondContact O-N 3.28Å; L26-S30 PolarHBondContact O-OG 2.91Å; L26-L86 HydrophobicContact CD1-CD1 3.6Å; L26-L86 HydrophobicContact CD1-CD2 4.33Å; L26-L126 HydrophobicContact CD1-CD1 4.3Å; L26-L126 HydrophobicContact CD2-CG 4.36Å; L26-Y129 HydrophobicContact CD2-CD1 3.78Å; L26-Y129 HydrophobicContact CD2-CG 4.26Å; L26-L244 HydrophobicContact CB-CD1 4.15Å
27G94.6Very high92.4Very high0 Ų027.6 Ų27.60%014%0.141CC..Hα-helixtrans-61.5-44.4174.500000113.1V23 V24 S30 M31V23-G27 PolarHBondContact O-N 3.14Å; V24-G27 PolarHBondContact O-N 3.49Å; G27-S30 PolarHBondContact O-N 3.38Å; G27-M31 WeakPolarHBondContact O-CB 3.45Å; G27-M31 PolarHBondContact O-N 2.75Å
28C95.3Very high92.6Very high33 Ų3325.9 Ų25.922%0.22312%0.124CC..Hα-helixtrans-68.5-35177-68.70000113V24 V25 M31 F32 L239V24-C28 WeakPolarHBondContact O-CB 3.48Å; V24-C28 PolarHBondContact O-N 2.87Å; V24-C28 PolarHBondContact O-SG 2.75Å; V24-C28 VanDerWaalsContact O-SG 3.33Å; V25-C28 PolarHBondContact O-N 3.48Å; C28-M31 WeakPolarHBondContact O-CB 3.27Å; C28-F32 WeakPolarHBondContact O-CD2 3.48Å; C28-F32 PolarHBondContact O-N 2.74Å; C28-L239 HydrophobicContact CB-CD1 4.43Å
29S94.4Very high92.6Very high0 Ų018.3 Ų18.30%010%0.095CC..Hα-helixtrans-66.7-45.2172.8176.60000110.6V25 L26 M31 F32 Y33 Y90 S236 T240V25-S29 WeakPolarHBondContact O-CB 3.44Å; V25-S29 PolarHBondContact O-N 3.16Å; L26-S29 PolarHBondContact O-N 3.25Å; S29-M31 VanDerWaalsContact C-N 3.31Å; S29-M31 PolarHBondContact O-N 2.98Å; S29-F32 PolarHBondContact O-N 3.45Å; S29-Y33 PolarHBondContact O-N 3.45Å; S29-Y90 WeakPolarHBondContact OG-CE2 3.37Å; S29-Y90 PolarHBondContact OG-OH 2.87Å; S29-S236 WeakPolarHBondContact O-CB 3.41Å; S29-S236 PolarHBondContact O-OG 2.65Å; S29-S236 PolarHBondContact OG-O 3.33Å; S29-S236 PolarHBondContact OG-OG 3.16Å; S29-T240 WeakPolarHBondContact CB-OG1 3.42Å; S29-T240 PolarHBondContact OG-OG1 3.08Å
30S93.2Very high92.5Very high0 Ų017.7 Ų17.70%09%0.092CC..Hα-helixtrans-67.6-30.1177.1-54.50000112.6L26 G27 Y33 C34 Y122 F156L26-S30 WeakPolarHBondContact O-CB 3.25Å; L26-S30 PolarHBondContact O-N 3.28Å; L26-S30 PolarHBondContact O-OG 2.91Å; G27-S30 PolarHBondContact O-N 3.38Å; S30-Y33 PolarHBondContact O-N 3.38Å; S30-C34 WeakPolarHBondContact O-CB 3.45Å; S30-C34 PolarHBondContact O-N 2.79Å; S30-C34 PolarHBondContact O-SG 2.89Å; S30-C34 VanDerWaalsContact O-SG 3.38Å; S30-Y122 PolarHBondContact OG-OH 3.07Å; S30-F156 WeakPolarHBondContact OG-CE2 3.05Å
31M95.1Very high92.4Very high30 Ų3014.9 Ų14.915%0.1488%0.077CC..Hα-helixtrans-54.7-53.4173179.8-177.377.900111.4G27 C28 S29 G35 L159 C162 G163G27-M31 WeakPolarHBondContact O-CB 3.45Å; G27-M31 PolarHBondContact O-N 2.75Å; C28-M31 WeakPolarHBondContact O-CB 3.27Å; S29-M31 VanDerWaalsContact C-N 3.31Å; S29-M31 PolarHBondContact O-N 2.98Å; M31-G35 PolarHBondContact O-N 3.4Å; M31-L159 WeakPolarHBondContact CB-O 3.28Å; M31-L159 VanDerWaalsContact CG-O 3.22Å; M31-L159 WeakPolarHBondContact CG-O 3.17Å; M31-C162 HydrophobicContact SD-CB 4.48Å; M31-G163 WeakPolarHBondContact O-CA 3.23Å
32F94.1Very high92.2Very high39 Ų3911.2 Ų11.217%0.1716%0.061CC..Hα-helixtrans-68.1-40.3179.9-67.9-67.9000112.6C28 S29 G35 C36 W232 L235 L239C28-F32 WeakPolarHBondContact O-CD2 3.48Å; C28-F32 PolarHBondContact O-N 2.74Å; S29-F32 PolarHBondContact O-N 3.45Å; F32-G35 PolarHBondContact O-N 3.33Å; F32-C36 PolarHBondContact O-N 3.4Å; F32-C36 PolarHBondContact O-SG 3.17Å; F32-W232 HydrophobicContact CB-CB 4.42Å; F32-W232 WeakPolarHBondContact CB-O 3.45Å; F32-W232 HydrophobicContact CD1-CB 4.38Å; F32-W232 HydrophobicContact CD1-CD2 4.02Å; F32-W232 AromaticContact CD1-CG 3.97Å; F32-W232 HydrophobicContact CD1-CG 3.97Å; F32-L235 HydrophobicContact CD1-CD2 4.23Å; F32-L235 HydrophobicContact CD2-CD2 4.09Å; F32-L235 HydrophobicContact CD2-CG 4.04Å; F32-L235 HydrophobicContact CE1-CD2 3.75Å; F32-L235 HydrophobicContact CE2-CD2 3.6Å; F32-L235 HydrophobicContact CE2-CG 3.89Å; F32-L235 HydrophobicContact CG-CD2 4.4Å; F32-L235 HydrophobicContact CZ-CD2 3.41Å; F32-L235 VanDerWaalsContact CZ-CD2 3.41Å; F32-L235 HydrophobicContact CZ-CG 4.22Å; F32-L239 HydrophobicContact CD2-CD1 3.75Å; F32-L239 HydrophobicContact CE2-CD1 3.67Å
33Y92.9Very high91.8Very high2 Ų210.8 Ų10.81%0.0086%0.059CC..Hα-helixtrans-62.2-52.8175.9169.1-111.3000111.6S29 S30 G35 C36 I37 T89 Y90 F93 Y122S29-Y33 PolarHBondContact O-N 3.45Å; S30-Y33 PolarHBondContact O-N 3.38Å; Y33-G35 VanDerWaalsContact C-N 3.29Å; Y33-G35 PolarHBondContact O-N 3.13Å; Y33-C36 PolarHBondContact O-N 3.46Å; Y33-I37 HydrophobicContact CE1-CG2 4.32Å; Y33-I37 PolarHBondContact O-N 2.96Å; Y33-I37 VanDerWaalsContact O-N 3.07Å; Y33-T89 HydrophobicContact CE2-CG2 4.46Å; Y33-Y90 HydrophobicContact CD1-CD1 4.31Å; Y33-Y90 AromaticContact CD1-CE1 3.88Å; Y33-Y90 HydrophobicContact CD1-CE1 3.88Å; Y33-Y90 AromaticContact CD2-CD1 3.57Å; Y33-Y90 HydrophobicContact CD2-CD1 3.57Å; Y33-Y90 AromaticContact CD2-CE1 3.95Å; Y33-Y90 HydrophobicContact CD2-CE1 3.95Å; Y33-Y90 HydrophobicContact CE2-CD1 4.12Å; Y33-Y90 AromaticContact CG-CD1 3.68Å; Y33-Y90 HydrophobicContact CG-CD1 3.68Å; Y33-Y90 AromaticContact CG-CE1 3.54Å; Y33-Y90 HydrophobicContact CG-CE1 3.54Å; Y33-F93 HydrophobicContact CD2-CD1 4.3Å; Y33-F93 HydrophobicContact CD2-CG 4.44Å; Y33-F93 HydrophobicContact CE2-CB 4.02Å; Y33-F93 HydrophobicContact CE2-CD1 4.16Å; Y33-F93 HydrophobicContact CE2-CD2 4.3Å; Y33-F93 AromaticContact CE2-CG 3.87Å; Y33-F93 HydrophobicContact CE2-CG 3.87Å; Y33-Y122 HydrophobicContact CD1-CE1 4.39Å; Y33-Y122 HydrophobicContact CD1-CE2 4.23Å; Y33-Y122 AromaticContact CD1-CZ 3.84Å; Y33-Y122 HydrophobicContact CE1-CD1 4.47Å; Y33-Y122 AromaticContact CE1-CE1 3.93Å; Y33-Y122 HydrophobicContact CE1-CE1 3.93Å; Y33-Y122 HydrophobicContact CE1-CE2 4.29Å; Y33-Y122 AromaticContact CE1-CZ 3.83Å
34C92.2Very high91.4Very high4 Ų410.8 Ų10.83%0.0276%0.059CC..Hα-helixtrans-64.5-32178.9-69.90000112.9S30 C36 M38 T160S30-C34 WeakPolarHBondContact O-CB 3.45Å; S30-C34 PolarHBondContact O-N 2.79Å; S30-C34 PolarHBondContact O-SG 2.89Å; S30-C34 VanDerWaalsContact O-SG 3.38Å; C34-C36 PolarHBondContact O-N 3.26Å; C34-M38 WeakPolarHBondContact O-CB 3.47Å; C34-M38 VanDerWaalsContact O-CG 3.3Å; C34-M38 WeakPolarHBondContact O-CG 3.33Å; C34-M38 PolarHBondContact O-N 2.83Å; C34-M38 VanDerWaalsContact O-N 3.1Å; C34-T160 HydrophobicContact CB-CG2 3.93Å
35G92Very high91Very high0 Ų08 Ų80%04%0.042CC..Hα-helixtrans-65.4-20.4171.800000114.4M31 F32 Y33 P39 G163 G167M31-G35 PolarHBondContact O-N 3.4Å; F32-G35 PolarHBondContact O-N 3.33Å; Y33-G35 VanDerWaalsContact C-N 3.29Å; Y33-G35 PolarHBondContact O-N 3.13Å; G35-P39 WeakPolarHBondContact O-CD 3.25Å; G35-P39 VanDerWaalsContact O-CG 3.3Å; G35-P39 WeakPolarHBondContact O-CG 3.44Å; G35-G163 WeakPolarHBondContact CA-O 3.47Å; G35-G167 VanDerWaalsContact O-CA 3.23Å; G35-G167 WeakPolarHBondContact O-CA 3.48Å
36C90.2Very high90.4Very high1 Ų17.4 Ų7.41%0.0074%0.039CC..Hα-helixtrans-91.6-48.5172.2-56.20000112.1F32 Y33 C34 L40 F93 Y229 W232 I233F32-C36 PolarHBondContact O-N 3.4Å; F32-C36 PolarHBondContact O-SG 3.17Å; Y33-C36 PolarHBondContact O-N 3.46Å; C34-C36 PolarHBondContact O-N 3.26Å; C36-L40 VanDerWaalsContact O-CB 3.23Å; C36-L40 WeakPolarHBondContact O-CB 3.29Å; C36-L40 PolarHBondContact O-N 2.89Å; C36-F93 HydrophobicContact CB-CE1 3.58Å; C36-F93 HydrophobicContact CB-CZ 4.26Å; C36-Y229 HydrophobicContact CB-CD1 3.88Å; C36-Y229 HydrophobicContact CB-CE1 4.48Å; C36-W232 VanDerWaalsContact SG-CB 3.52Å; C36-I233 HydrophobicContact CB-CD1 4.38Å; C36-I233 HydrophobicContact CB-CG1 4.19Å
37I88.5Confident89.4Confident13 Ų137.6 Ų7.67%0.0674%0.04CC..Hα-helixtrans-70.3-33.5-173.9-170.5165.1000113.5Y33 R41 F93Y33-I37 HydrophobicContact CE1-CG2 4.32Å; Y33-I37 PolarHBondContact O-N 2.96Å; Y33-I37 VanDerWaalsContact O-N 3.07Å; I37-R41 WeakPolarHBondContact O-CB 3.37Å; I37-R41 PolarHBondContact O-N 3.07Å; I37-F93 HydrophobicContact CB-CD2 4.42Å; I37-F93 HydrophobicContact CB-CE1 4.33Å; I37-F93 HydrophobicContact CB-CE2 3.66Å; I37-F93 HydrophobicContact CB-CZ 3.62Å; I37-F93 HydrophobicContact CD1-CD2 4.06Å; I37-F93 HydrophobicContact CD1-CE2 3.81Å; I37-F93 HydrophobicContact CG1-CD2 4.36Å; I37-F93 HydrophobicContact CG1-CE2 3.62Å; I37-F93 HydrophobicContact CG1-CZ 4.07Å
38M90.9Very high88Confident17 Ų1711 Ų118%0.0846%0.062CC..Hα-helixtrans-70.6-47.1-177-64.5-62.9168.500113C34 R41 T42 W164 F168C34-M38 WeakPolarHBondContact O-CB 3.47Å; C34-M38 VanDerWaalsContact O-CG 3.3Å; C34-M38 WeakPolarHBondContact O-CG 3.33Å; C34-M38 PolarHBondContact O-N 2.83Å; C34-M38 VanDerWaalsContact O-N 3.1Å; M38-R41 VanDerWaalsContact SD-CZ 3.57Å; M38-R41 PolarHBondContact SD-NH2 3.19Å; M38-R41 VanDerWaalsContact SD-NH2 3.37Å; M38-T42 PolarHBondContact O-N 2.87Å; M38-T42 PolarHBondContact O-OG1 3.01Å; M38-W164 HydrophobicContact CB-CG 4.42Å; M38-W164 HydrophobicContact CE-CZ2 3.74Å; M38-W164 HydrophobicContact CG-CD2 4.01Å; M38-W164 HydrophobicContact CG-CG 4.05Å; M38-W164 HydrophobicContact CG-CZ2 4.32Å; M38-W164 HydrophobicContact SD-CZ2 4.17Å; M38-F168 HydrophobicContact CB-CE2 4.18Å; M38-F168 HydrophobicContact CB-CZ 4.17Å
39P88.9Confident86.5Confident0 Ų010.7 Ų10.70%06%0.058CC..Hα-helixtrans-62.1-47.8170.9-2234000112.4G35 R41 T42 Y43 F168 S171G35-P39 WeakPolarHBondContact O-CD 3.25Å; G35-P39 VanDerWaalsContact O-CG 3.3Å; G35-P39 WeakPolarHBondContact O-CG 3.44Å; P39-R41 VanDerWaalsContact C-N 3.32Å; P39-R41 PolarHBondContact O-N 2.99Å; P39-T42 PolarHBondContact O-N 3Å; P39-Y43 HydrophobicContact CB-CD2 4.21Å; P39-Y43 HydrophobicContact CB-CE2 3.99Å; P39-Y43 WeakPolarHBondContact O-CD2 3.43Å; P39-Y43 PolarHBondContact O-N 3.21Å; P39-F168 HydrophobicContact CB-CD1 4.04Å; P39-F168 HydrophobicContact CB-CE1 4.07Å; P39-F168 HydrophobicContact CG-CD1 4Å; P39-F168 HydrophobicContact CG-CE1 4.16Å; P39-F168 HydrophobicContact CG-CG 4.23Å; P39-S171 WeakPolarHBondContact CB-OG 3.42Å
40L86.6Confident84.5Confident6 Ų616.7 Ų16.73%0.03110%0.098CC..Hα-helixtrans-58.5-43.6-176.7-169.266.2000111.8C36 L44 F93 F96 I97 V100 W214C36-L40 VanDerWaalsContact O-CB 3.23Å; C36-L40 WeakPolarHBondContact O-CB 3.29Å; C36-L40 PolarHBondContact O-N 2.89Å; L40-L44 WeakPolarHBondContact O-CB 3.38Å; L40-L44 PolarHBondContact O-N 3.25Å; L40-F93 HydrophobicContact CD2-CE2 4.15Å; L40-F93 HydrophobicContact CD2-CZ 3.68Å; L40-F96 HydrophobicContact CD2-CD1 3.63Å; L40-F96 HydrophobicContact CD2-CE1 3.68Å; L40-F96 HydrophobicContact CG-CE1 4.23Å; L40-I97 HydrophobicContact CD2-CG1 4.18Å; L40-V100 HydrophobicContact CD1-CB 4.16Å; L40-V100 HydrophobicContact CD1-CG1 3.82Å; L40-V100 HydrophobicContact CD1-CG2 4.21Å; L40-V100 HydrophobicContact CD2-CG2 4.21Å; L40-V100 HydrophobicContact CG-CG2 4.22Å; L40-W214 HydrophobicContact CD1-CH2 4.1Å
41R88.6Confident83Confident10 Ų1018.9 Ų18.94%0.03812%0.121CC..Hα-helixtrans-57.1-47.7172.5176.7-176.573.5168.91.5112.2I37 M38 P39 S45 L58 Y62 E290 F418I37-R41 WeakPolarHBondContact O-CB 3.37Å; I37-R41 PolarHBondContact O-N 3.07Å; M38-R41 VanDerWaalsContact SD-CZ 3.57Å; M38-R41 PolarHBondContact SD-NH2 3.19Å; M38-R41 VanDerWaalsContact SD-NH2 3.37Å; P39-R41 VanDerWaalsContact C-N 3.32Å; P39-R41 PolarHBondContact O-N 2.99Å; R41-S45 PolarHBondContact O-N 3.02Å; R41-L58 HydrophobicContact CG-CD1 4.32Å; R41-L58 HydrophobicContact CG-CD2 4.03Å; R41-Y62 WeakPolarHBondContact CD-OH 2.99Å; R41-Y62 PolarHBondContact NH1-OH 3.19Å; R41-E290 IonicContact CZ-OE1 3.96Å; R41-E290 VanDerWaalsContact CZ-OE1 3.24Å; R41-E290 IonicContact NH1-OE1 2.77Å; R41-E290 PolarHBondContact NH1-OE1 2.86Å; R41-E290 IonicContact NH2-OE1 3.96Å; R41-E290 PolarHBondContact NH2-OE1 3Å; R41-F418 HydrophobicContact CG-CZ 4Å
42T88.9Confident82.3Confident0 Ų019.9 Ų19.90%013%0.127CC..Hα-helixtrans-67.5-51.2-175-51.60000111.7M38 P39 L44 S45 L46 V294 L315M38-T42 PolarHBondContact O-N 2.87Å; M38-T42 PolarHBondContact O-OG1 3.01Å; P39-T42 PolarHBondContact O-N 3Å; T42-L44 PolarHBondContact O-N 3.32Å; T42-S45 PolarHBondContact O-N 2.88Å; T42-S45 PolarHBondContact O-OG 3.33Å; T42-L46 HydrophobicContact CG2-CD1 3.73Å; T42-L46 WeakPolarHBondContact O-CD1 3.39Å; T42-L46 VanDerWaalsContact O-CG 3.29Å; T42-L46 WeakPolarHBondContact O-CG 3.06Å; T42-L46 PolarHBondContact O-N 2.96Å; T42-L46 VanDerWaalsContact O-N 3.17Å; T42-V294 HydrophobicContact CG2-CG1 3.9Å; T42-V294 VanDerWaalsContact CG2-O 3.25Å; T42-V294 WeakPolarHBondContact CG2-O 3.2Å; T42-V294 VanDerWaalsContact OG1-CG1 3.3Å; T42-V294 WeakPolarHBondContact OG1-CG1 3.32Å; T42-L315 HydrophobicContact CG2-CD1 3.32Å
43Y85.3Confident81.8Confident0 Ų018.7 Ų18.70%012%0.123CC..Hα-helixtrans-65.3-32.7179.6-65.1-70.2000111.5P39 L46 S47 S171 L175 W189 Q308 G312P39-Y43 HydrophobicContact CB-CD2 4.21Å; P39-Y43 HydrophobicContact CB-CE2 3.99Å; P39-Y43 WeakPolarHBondContact O-CD2 3.43Å; P39-Y43 PolarHBondContact O-N 3.21Å; Y43-L46 PolarHBondContact O-N 3.12Å; Y43-S47 PolarHBondContact O-N 2.96Å; Y43-S47 PolarHBondContact O-OG 2.84Å; Y43-S171 VanDerWaalsContact CE2-CB 3.46Å; Y43-L175 HydrophobicContact CD1-CD1 4.26Å; Y43-L175 HydrophobicContact CE1-CD1 3.49Å; Y43-L175 VanDerWaalsContact CE1-CD1 3.49Å; Y43-L175 HydrophobicContact CE2-CD1 4.36Å; Y43-W189 AromaticContact CD1-CH2 3.72Å; Y43-W189 HydrophobicContact CD1-CH2 3.72Å; Y43-W189 AromaticContact CD1-CZ3 3.9Å; Y43-W189 HydrophobicContact CD1-CZ3 3.9Å; Y43-W189 HydrophobicContact CE1-CZ3 4.47Å; Y43-Q308 HydrophobicContact CD1-CG 4.21Å; Y43-Q308 HydrophobicContact CE1-CG 4.11Å; Y43-G312 WeakPolarHBondContact OH-CA 3.44Å
44L84.9Confident81.4Confident0 Ų018.6 Ų18.60%012%0.123CC..Hα-helixtrans-64.7-44.7174.4177.959.1000111.4L40 T42 L46 S47 A54 L58 F96 V100 Y103 L108L40-L44 WeakPolarHBondContact O-CB 3.38Å; L40-L44 PolarHBondContact O-N 3.25Å; T42-L44 PolarHBondContact O-N 3.32Å; L44-L46 PolarHBondContact O-N 2.89Å; L44-S47 VanDerWaalsContact O-CB 3.3Å; L44-S47 WeakPolarHBondContact O-CB 3.35Å; L44-S47 PolarHBondContact O-N 3.43Å; L44-S47 PolarHBondContact O-OG 3.38Å; L44-A54 HydrophobicContact CD1-CB 3.55Å; L44-A54 HydrophobicContact CG-CB 3.8Å; L44-A54 WeakPolarHBondContact O-CB 3.03Å; L44-L58 HydrophobicContact CD2-CD1 4.42Å; L44-L58 HydrophobicContact CD2-CD2 4.09Å; L44-L58 HydrophobicContact CD2-CG 4.17Å; L44-L58 HydrophobicContact CG-CD1 4.29Å; L44-F96 HydrophobicContact CD2-CE1 4.45Å; L44-F96 HydrophobicContact CD2-CZ 3.77Å; L44-V100 HydrophobicContact CD1-CG1 4.34Å; L44-V100 HydrophobicContact CD2-CG2 4.09Å; L44-Y103 HydrophobicContact CD1-CE2 4.3Å; L44-L108 HydrophobicContact CD1-CD2 4.26Å; L44-L108 HydrophobicContact CD2-CD1 4.2Å
45S85.2Confident81.2Confident1 Ų118.5 Ų18.51%0.00712%0.122CC..Hα-helixtrans-66.8-25.4178.471.20000113.9R41 T42 S47 A295 K421R41-S45 PolarHBondContact O-N 3.02Å; T42-S45 PolarHBondContact O-N 2.88Å; T42-S45 PolarHBondContact O-OG 3.33Å; S45-S47 VanDerWaalsContact C-N 3.33Å; S45-A295 WeakPolarHBondContact OG-CB 3.47Å; S45-K421 WeakPolarHBondContact O-CE 3.42Å; S45-K421 PolarHBondContact O-NZ 3.3Å
46L82.4Confident81.1Confident0 Ų022.6 Ų22.60%014%0.143CC..THydrogen-bonded Turntrans-86.40179.8-70.1167.1000114.1T42 Y43 L44 W189 M298 Q299 V311T42-L46 HydrophobicContact CG2-CD1 3.73Å; T42-L46 WeakPolarHBondContact O-CD1 3.39Å; T42-L46 VanDerWaalsContact O-CG 3.29Å; T42-L46 WeakPolarHBondContact O-CG 3.06Å; T42-L46 PolarHBondContact O-N 2.96Å; T42-L46 VanDerWaalsContact O-N 3.17Å; Y43-L46 PolarHBondContact O-N 3.12Å; L44-L46 PolarHBondContact O-N 2.89Å; L46-W189 HydrophobicContact CB-CE3 4.44Å; L46-W189 HydrophobicContact CB-CH2 3.33Å; L46-W189 HydrophobicContact CB-CZ2 4.09Å; L46-W189 HydrophobicContact CB-CZ3 3.55Å; L46-W189 HydrophobicContact CD1-CH2 4.12Å; L46-W189 HydrophobicContact CD1-CZ3 3.64Å; L46-W189 HydrophobicContact CG-CH2 4.35Å; L46-W189 HydrophobicContact CG-CZ3 4.18Å; L46-M298 HydrophobicContact CD1-CB 3.89Å; L46-M298 HydrophobicContact CD2-CB 3.87Å; L46-M298 HydrophobicContact CG-CB 4.46Å; L46-Q299 HydrophobicContact CD2-CB 3.49Å; L46-Q299 VanDerWaalsContact CD2-CB 3.49Å; L46-Q299 HydrophobicContact CD2-CG 3.85Å; L46-V311 HydrophobicContact CD1-CG1 3.75Å
47S73.9Confident81.1Confident3 Ų322.6 Ų22.62%0.02114%0.144CC..SBendtrans-70.1138.5-174.5-610000112.7Y43 L44 S45 D49 W214Y43-S47 PolarHBondContact O-N 2.96Å; Y43-S47 PolarHBondContact O-OG 2.84Å; L44-S47 VanDerWaalsContact O-CB 3.3Å; L44-S47 WeakPolarHBondContact O-CB 3.35Å; L44-S47 PolarHBondContact O-N 3.43Å; L44-S47 PolarHBondContact O-OG 3.38Å; S45-S47 VanDerWaalsContact C-N 3.33Å; S47-D49 VanDerWaalsContact C-N 3.33Å; S47-D49 VanDerWaalsContact CB-OD1 3.3Å; S47-D49 WeakPolarHBondContact CB-OD1 3.34Å; S47-D49 PolarHBondContact O-N 2.89Å; S47-W214 PolarHBondContact OG-NE1 3.26Å
48P64Low81.3Confident72 Ų7222.2 Ų22.247%0.46814%0.141SC..  trans-74.785175.330-33.5000110.6I212P48-I212 VanDerWaalsContact CG-O 3.28Å; P48-I212 WeakPolarHBondContact CG-O 3.43Å
49D64.6Low81.5Confident27 Ų2721.8 Ų21.814%0.14414%0.14CC..  trans-86.4128.5-170.6-76.2-1.9000114.4S47 G51 V53 A54 Y103S47-D49 VanDerWaalsContact C-N 3.33Å; S47-D49 VanDerWaalsContact CB-OD1 3.3Å; S47-D49 WeakPolarHBondContact CB-OD1 3.34Å; S47-D49 PolarHBondContact O-N 2.89Å; D49-G51 PolarHBondContact O-N 2.75Å; D49-V53 PolarHBondContact OD2-N 3.48Å; D49-A54 WeakPolarHBondContact OD2-CA 3.39Å; D49-A54 WeakPolarHBondContact OD2-CB 3.49Å; D49-A54 PolarHBondContact OD2-N 2.71Å; D49-Y103 PolarHBondContact OD1-OH 2.86Å; D49-Y103 PolarHBondContact OD2-OH 3.43Å; D49-Y103 VanDerWaalsContact OD2-OH 3.1Å
50C52.4Low81.7Confident125 Ų12524.5 Ų24.585%0.84516%0.155SC*.THydrogen-bonded Turntrans-71.774.6162-60.60000111.3
51G62.1Low82.1Confident47 Ų4724.4 Ų24.449%0.48515%0.154SC..THydrogen-bonded Turntrans12019.6174.600000116.2D49 V53D49-G51 PolarHBondContact O-N 2.75Å; G51-V53 PolarHBondContact O-N 3.48Å
52N79.4Confident82.4Confident51 Ų5124.4 Ų24.427%0.27315%0.154SC..SBendtrans60.129.2174.3-46.4-36.9000114.4A54 S55 I56 P422N52-A54 PolarHBondContact O-N 2.71Å; N52-S55 WeakPolarHBondContact O-CB 3.33Å; N52-S55 PolarHBondContact O-N 2.97Å; N52-S55 VanDerWaalsContact O-N 3.16Å; N52-I56 WeakPolarHBondContact O-CG1 3.38Å; N52-I56 PolarHBondContact O-N 3.04Å; N52-P422 HydrophobicContact CB-CB 3.8Å; N52-P422 HydrophobicContact CB-CG 4.14Å; N52-P422 VanDerWaalsContact ND2-CB 3.33Å; N52-P422 WeakPolarHBondContact ND2-CB 3.49Å
53V84.8Confident82.7Confident13 Ų1327.5 Ų27.58%0.07917%0.173CC..Hα-helixtrans-71-36.7-164.7-176.90000112.3D49 G51 I56 A57 H105 L108D49-V53 PolarHBondContact OD2-N 3.48Å; G51-V53 PolarHBondContact O-N 3.48Å; V53-I56 PolarHBondContact O-N 2.71Å; V53-A57 VanDerWaalsContact O-CB 3.25Å; V53-A57 WeakPolarHBondContact O-CB 3.27Å; V53-A57 PolarHBondContact O-N 3.23Å; V53-H105 VanDerWaalsContact CG2-CD2 3.5Å; V53-H105 WeakPolarHBondContact CG2-CD2 3.44Å; V53-L108 HydrophobicContact CG1-CD2 4.49Å
54A84.1Confident83.2Confident0 Ų028.6 Ų28.60%018%0.179CC..Hα-helixtrans-61.7-42.4170.700000111.7L44 D49 N52 A57 L58L44-A54 HydrophobicContact CD1-CB 3.55Å; L44-A54 HydrophobicContact CG-CB 3.8Å; L44-A54 WeakPolarHBondContact O-CB 3.03Å; D49-A54 WeakPolarHBondContact OD2-CA 3.39Å; D49-A54 WeakPolarHBondContact OD2-CB 3.49Å; D49-A54 PolarHBondContact OD2-N 2.71Å; N52-A54 PolarHBondContact O-N 2.71Å; A54-A57 PolarHBondContact O-N 2.95Å; A54-L58 VanDerWaalsContact O-CB 3.31Å; A54-L58 WeakPolarHBondContact O-CB 3.35Å; A54-L58 VanDerWaalsContact O-CG 3.29Å; A54-L58 WeakPolarHBondContact O-CG 3.24Å; A54-L58 PolarHBondContact O-N 2.78Å
55S88Confident83.6Confident3 Ų328.6 Ų28.62%0.02118%0.179CC..Hα-helixtrans-64-42.2177.5-59.30000111.4N52 S59 F418N52-S55 WeakPolarHBondContact O-CB 3.33Å; N52-S55 PolarHBondContact O-N 2.97Å; N52-S55 VanDerWaalsContact O-N 3.16Å; S55-S59 VanDerWaalsContact O-CB 3.31Å; S55-S59 WeakPolarHBondContact O-CB 3.09Å; S55-S59 PolarHBondContact O-N 2.95Å; S55-F418 WeakPolarHBondContact CB-O 3.24Å
56I90.4Very high84Confident85 Ų8528.8 Ų28.844%0.43618%0.181SC..Hα-helixtrans-65.6-45.6174.2-66165.8000111N52 V53 S59 L60 L109N52-I56 WeakPolarHBondContact O-CG1 3.38Å; N52-I56 PolarHBondContact O-N 3.04Å; V53-I56 PolarHBondContact O-N 2.71Å; I56-S59 PolarHBondContact O-N 3.43Å; I56-L60 VanDerWaalsContact O-CB 3.28Å; I56-L60 WeakPolarHBondContact O-CB 3.42Å; I56-L60 PolarHBondContact O-N 3.14Å; I56-L109 HydrophobicContact CG2-CD2 4.24Å
57A90.1Very high84.4Confident2 Ų231.8 Ų31.82%0.01720%0.202CC..Hα-helixtrans-64.6-43179.900000112.4V53 A54 L60 L61 L108 L109 A112V53-A57 VanDerWaalsContact O-CB 3.25Å; V53-A57 WeakPolarHBondContact O-CB 3.27Å; V53-A57 PolarHBondContact O-N 3.23Å; A54-A57 PolarHBondContact O-N 2.95Å; A57-L60 PolarHBondContact O-N 2.78Å; A57-L61 WeakPolarHBondContact O-CB 3.2Å; A57-L61 PolarHBondContact O-N 3.3Å; A57-L108 HydrophobicContact CB-CD2 4.13Å; A57-L108 HydrophobicContact CB-CG 4.02Å; A57-L109 HydrophobicContact CB-CD2 3.89Å; A57-A112 HydrophobicContact CB-CB 4.11Å; A57-A112 WeakPolarHBondContact O-CB 3.28Å
58L92.2Very high85.3Confident4 Ų432 Ų322%0.02120%0.203CC..Hα-helixtrans-67.2-41.6175.6-72.3174.4000111.5R41 L44 A54 L60 L61 Y62 F418R41-L58 HydrophobicContact CG-CD1 4.32Å; R41-L58 HydrophobicContact CG-CD2 4.03Å; L44-L58 HydrophobicContact CD2-CD1 4.42Å; L44-L58 HydrophobicContact CD2-CD2 4.09Å; L44-L58 HydrophobicContact CD2-CG 4.17Å; L44-L58 HydrophobicContact CG-CD1 4.29Å; A54-L58 VanDerWaalsContact O-CB 3.31Å; A54-L58 WeakPolarHBondContact O-CB 3.35Å; A54-L58 VanDerWaalsContact O-CG 3.29Å; A54-L58 WeakPolarHBondContact O-CG 3.24Å; A54-L58 PolarHBondContact O-N 2.78Å; L58-L60 PolarHBondContact O-N 3.4Å; L58-L61 PolarHBondContact O-N 3.22Å; L58-Y62 WeakPolarHBondContact O-CD2 3.45Å; L58-Y62 PolarHBondContact O-N 2.79Å; L58-Y62 VanDerWaalsContact O-N 3.12Å; L58-F418 HydrophobicContact CB-CB 4.3Å; L58-F418 HydrophobicContact CB-CD1 4.04Å; L58-F418 HydrophobicContact CB-CD2 3.99Å; L58-F418 HydrophobicContact CB-CE1 4.41Å; L58-F418 HydrophobicContact CB-CE2 4.37Å; L58-F418 HydrophobicContact CB-CG 3.84Å; L58-F418 HydrophobicContact CD1-CD1 3.96Å; L58-F418 HydrophobicContact CD1-CE1 3.73Å; L58-F418 HydrophobicContact CD1-CZ 4.14Å
59S94.3Very high86.4Confident9 Ų928.5 Ų28.56%0.06318%0.181CC..Hα-helixtrans-59-48.1172.7-178.20000111.4S55 I56 L61 Y62 V63 S415S55-S59 VanDerWaalsContact O-CB 3.31Å; S55-S59 WeakPolarHBondContact O-CB 3.09Å; S55-S59 PolarHBondContact O-N 2.95Å; I56-S59 PolarHBondContact O-N 3.43Å; S59-L61 PolarHBondContact O-N 3.47Å; S59-Y62 PolarHBondContact O-N 3.17Å; S59-Y62 VanDerWaalsContact O-N 3.1Å; S59-V63 WeakPolarHBondContact O-CG2 3.26Å; S59-V63 PolarHBondContact O-N 3.17Å; S59-S415 PolarHBondContact O-OG 3.22Å; S59-S415 PolarHBondContact OG-O 2.74Å; S59-S415 PolarHBondContact OG-OG 3.5Å
60L94Very high87.4Confident57 Ų5729.3 Ų29.330%0.29819%0.185SC..Hα-helixtrans-60.8-43.5178.7-176.459.9000112.5I56 A57 L58 Y62 V63 V64 L109 I113I56-L60 VanDerWaalsContact O-CB 3.28Å; I56-L60 WeakPolarHBondContact O-CB 3.42Å; I56-L60 PolarHBondContact O-N 3.14Å; A57-L60 PolarHBondContact O-N 2.78Å; L58-L60 PolarHBondContact O-N 3.4Å; L60-Y62 VanDerWaalsContact C-N 3.27Å; L60-Y62 PolarHBondContact O-N 2.94Å; L60-V63 PolarHBondContact O-N 3.22Å; L60-V64 HydrophobicContact CD1-CG2 3.96Å; L60-V64 HydrophobicContact CG-CG2 4.37Å; L60-V64 WeakPolarHBondContact O-CB 3.44Å; L60-V64 VanDerWaalsContact O-CG2 3.23Å; L60-V64 WeakPolarHBondContact O-CG2 3.44Å; L60-V64 PolarHBondContact O-N 2.9Å; L60-L109 HydrophobicContact CD2-CD2 4.28Å; L60-I113 HydrophobicContact CD2-CD1 3.93Å; L60-I113 HydrophobicContact CD2-CG1 3.59Å; L60-I113 HydrophobicContact CG-CG1 3.95Å
61L93.8Very high88.9Confident4 Ų426.6 Ų26.62%0.02116%0.162CC..Hα-helixtrans-53.1-45.9172.6-176.2160.6000110.9A57 L58 S59 S65 A112 I115 G116A57-L61 WeakPolarHBondContact O-CB 3.2Å; A57-L61 PolarHBondContact O-N 3.3Å; L58-L61 PolarHBondContact O-N 3.22Å; S59-L61 PolarHBondContact O-N 3.47Å; L61-S65 VanDerWaalsContact O-CB 3.23Å; L61-S65 WeakPolarHBondContact O-CB 3.08Å; L61-S65 PolarHBondContact O-N 3.3Å; L61-A112 HydrophobicContact CB-CB 4.21Å; L61-I115 HydrophobicContact CD1-CB 4.04Å; L61-I115 HydrophobicContact CD1-CD1 4.35Å; L61-I115 HydrophobicContact CD1-CG2 3.83Å; L61-I115 HydrophobicContact CD2-CG2 4.29Å; L61-I115 HydrophobicContact CG-CB 4.32Å; L61-I115 HydrophobicContact CG-CG2 4.04Å; L61-G116 WeakPolarHBondContact O-CA 3.47Å
62Y95.4Very high89.6Confident9 Ų924.8 Ų24.84%0.03514%0.14CC..Hα-helixtrans-76-34.5-178.7-76.7-62.4000114.3R41 L58 S59 L60 S65 A66 T411 M414 F418R41-Y62 WeakPolarHBondContact CD-OH 2.99Å; R41-Y62 PolarHBondContact NH1-OH 3.19Å; L58-Y62 WeakPolarHBondContact O-CD2 3.45Å; L58-Y62 PolarHBondContact O-N 2.79Å; L58-Y62 VanDerWaalsContact O-N 3.12Å; S59-Y62 PolarHBondContact O-N 3.17Å; S59-Y62 VanDerWaalsContact O-N 3.1Å; L60-Y62 VanDerWaalsContact C-N 3.27Å; L60-Y62 PolarHBondContact O-N 2.94Å; Y62-S65 WeakPolarHBondContact O-CB 3.39Å; Y62-S65 PolarHBondContact O-N 3.25Å; Y62-A66 PolarHBondContact O-N 2.88Å; Y62-T411 HydrophobicContact CD1-CG2 3.97Å; Y62-T411 HydrophobicContact CE1-CG2 4.48Å; Y62-M414 HydrophobicContact CD1-CB 4.08Å; Y62-M414 HydrophobicContact CD1-SD 4.04Å; Y62-M414 HydrophobicContact CD2-CB 3.99Å; Y62-M414 HydrophobicContact CE1-CB 4.38Å; Y62-M414 HydrophobicContact CE1-SD 3.56Å; Y62-M414 VanDerWaalsContact CE1-SD 3.56Å; Y62-M414 HydrophobicContact CE2-CB 4.31Å; Y62-M414 HydrophobicContact CG-CB 3.88Å; Y62-F418 AromaticContact CD2-CD2 3.79Å; Y62-F418 HydrophobicContact CD2-CD2 3.79Å; Y62-F418 AromaticContact CD2-CE2 3.8Å; Y62-F418 HydrophobicContact CD2-CE2 3.8Å; Y62-F418 AromaticContact CE2-CD2 3.97Å; Y62-F418 HydrophobicContact CE2-CD2 3.97Å; Y62-F418 AromaticContact CE2-CE2 3.48Å; Y62-F418 HydrophobicContact CE2-CE2 3.48Å; Y62-F418 VanDerWaalsContact CE2-CE2 3.48Å; Y62-F418 HydrophobicContact CE2-CZ 4.48Å
63V95.3Very high89Confident65 Ų6523 Ų2339%0.39413%0.133SC..Hα-helixtrans-62.2-47.4169.5179.10000110.5S59 L60 S65 A66 S67 S415S59-V63 WeakPolarHBondContact O-CG2 3.26Å; S59-V63 PolarHBondContact O-N 3.17Å; L60-V63 PolarHBondContact O-N 3.22Å; V63-S65 VanDerWaalsContact C-N 3.29Å; V63-S65 PolarHBondContact O-N 2.71Å; V63-A66 WeakPolarHBondContact O-CB 3.46Å; V63-A66 PolarHBondContact O-N 3.37Å; V63-A66 VanDerWaalsContact O-N 3.14Å; V63-S67 PolarHBondContact O-N 3.27Å; V63-S67 PolarHBondContact O-OG 3.33Å; V63-S415 WeakPolarHBondContact CG2-OG 3.24Å
64V95.2Very high88Confident23 Ų2322.9 Ų22.914%0.13913%0.133CC..Hα-helixtrans-67.5-33.4-179.6-179.50000110.5L60 S67 S68 I113 G116 L117L60-V64 HydrophobicContact CD1-CG2 3.96Å; L60-V64 HydrophobicContact CG-CG2 4.37Å; L60-V64 WeakPolarHBondContact O-CB 3.44Å; L60-V64 VanDerWaalsContact O-CG2 3.23Å; L60-V64 WeakPolarHBondContact O-CG2 3.44Å; L60-V64 PolarHBondContact O-N 2.9Å; V64-S67 PolarHBondContact O-N 3.1Å; V64-S68 VanDerWaalsContact O-CB 3.27Å; V64-S68 WeakPolarHBondContact O-CB 3.38Å; V64-S68 PolarHBondContact O-N 3.29Å; V64-S68 PolarHBondContact O-OG 3.16Å; V64-I113 HydrophobicContact CG1-CG2 4.45Å; V64-G116 CarbonylContact C-O 3.57Å; V64-L117 HydrophobicContact CG1-CB 4.44Å; V64-L117 HydrophobicContact CG1-CD2 3.63Å; V64-L117 HydrophobicContact CG1-CG 3.69Å
65S94Very high87.1Confident0 Ų029.6 Ų29.60%016%0.162CC..Hα-helixtrans-62.3-38.7169.9-1650000112.9L61 Y62 V63 S68 S69 G116 Q119 G120L61-S65 VanDerWaalsContact O-CB 3.23Å; L61-S65 WeakPolarHBondContact O-CB 3.08Å; L61-S65 PolarHBondContact O-N 3.3Å; Y62-S65 WeakPolarHBondContact O-CB 3.39Å; Y62-S65 PolarHBondContact O-N 3.25Å; V63-S65 VanDerWaalsContact C-N 3.29Å; V63-S65 PolarHBondContact O-N 2.71Å; S65-S68 WeakPolarHBondContact CA-OG 3.36Å; S65-S68 PolarHBondContact O-OG 3.38Å; S65-S69 WeakPolarHBondContact O-CB 3.42Å; S65-S69 PolarHBondContact O-N 2.88Å; S65-S69 VanDerWaalsContact O-N 3.12Å; S65-S69 PolarHBondContact O-OG 3.47Å; S65-G116 WeakPolarHBondContact CA-O 3.41Å; S65-G116 PolarHBondContact N-O 3.32Å; S65-Q119 PolarHBondContact OG-NE2 3.37Å; S65-G120 PolarHBondContact OG-N 3.1Å
66A93.2Very high85.9Confident6 Ų630.4 Ų30.45%0.0517%0.167CC..Hα-helixtrans-67.6-46.7174.600000111.3Y62 V63 S69 L70 V408 V412Y62-A66 PolarHBondContact O-N 2.88Å; V63-A66 WeakPolarHBondContact O-CB 3.46Å; V63-A66 PolarHBondContact O-N 3.37Å; V63-A66 VanDerWaalsContact O-N 3.14Å; A66-S69 WeakPolarHBondContact O-CB 3.34Å; A66-S69 PolarHBondContact O-N 3.21Å; A66-L70 PolarHBondContact O-N 2.82Å; A66-V408 HydrophobicContact CB-CG1 4.34Å; A66-V412 HydrophobicContact CB-CG2 3.79Å
67S91.5Very high84.6Confident62 Ų6227.3 Ų27.343%0.43416%0.155SC..Hα-helixtrans-62.2-45.3177.4-630000112.7V63 V64 S69 L70 L71V63-S67 PolarHBondContact O-N 3.27Å; V63-S67 PolarHBondContact O-OG 3.33Å; V64-S67 PolarHBondContact O-N 3.1Å; S67-S69 VanDerWaalsContact C-N 3.3Å; S67-S69 PolarHBondContact O-N 3.4Å; S67-L70 PolarHBondContact O-N 3.12Å; S67-L71 WeakPolarHBondContact O-CG 3.31Å; S67-L71 PolarHBondContact O-N 2.89Å
68S91.5Very high83.4Confident7 Ų732 Ų325%0.04917%0.172CC..Hα-helixtrans-67.6-30.4179.167.20000112.6V64 S65 L71 Y72 G116 L117 P121V64-S68 VanDerWaalsContact O-CB 3.27Å; V64-S68 WeakPolarHBondContact O-CB 3.38Å; V64-S68 PolarHBondContact O-N 3.29Å; V64-S68 PolarHBondContact O-OG 3.16Å; S65-S68 WeakPolarHBondContact CA-OG 3.36Å; S65-S68 PolarHBondContact O-OG 3.38Å; S68-L71 CarbonylContact O-C 3.56Å; S68-L71 PolarHBondContact O-N 3.42Å; S68-Y72 PolarHBondContact O-N 3.06Å; S68-G116 PolarHBondContact OG-O 3.28Å; S68-L117 WeakPolarHBondContact CB-O 3.42Å; S68-P121 VanDerWaalsContact OG-CD 3.31Å; S68-P121 WeakPolarHBondContact OG-CD 3.36Å
69S88.6Confident82.2Confident0 Ų040 Ų400%021%0.209CC..Hα-helixtrans-62.9-45.2171.9-60.10000112.2S65 A66 S67 L71 Y72 G120 N124 T404 H407S65-S69 WeakPolarHBondContact O-CB 3.42Å; S65-S69 PolarHBondContact O-N 2.88Å; S65-S69 VanDerWaalsContact O-N 3.12Å; S65-S69 PolarHBondContact O-OG 3.47Å; A66-S69 WeakPolarHBondContact O-CB 3.34Å; A66-S69 PolarHBondContact O-N 3.21Å; S67-S69 VanDerWaalsContact C-N 3.3Å; S67-S69 PolarHBondContact O-N 3.4Å; S69-L71 VanDerWaalsContact C-N 3.26Å; S69-L71 PolarHBondContact O-N 2.78Å; S69-Y72 VanDerWaalsContact O-CB 3.28Å; S69-Y72 WeakPolarHBondContact O-CB 3.46Å; S69-Y72 PolarHBondContact O-N 3.38Å; S69-G120 WeakPolarHBondContact OG-CA 3.19Å; S69-N124 PolarHBondContact O-ND2 2.68Å; S69-T404 WeakPolarHBondContact O-CG2 3.43Å; S69-H407 PolarHBondContact OG-CD2 2.79Å; S69-H407 VanDerWaalsContact OG-CD2 3.27Å
70L86Confident81.1Confident43 Ų4342.4 Ų42.423%0.22522%0.221CC..Hα-helixtrans-63.6-34.3176.8-66.9171.5000112A66 S67 L264 N267 I271 V408A66-L70 PolarHBondContact O-N 2.82Å; S67-L70 PolarHBondContact O-N 3.12Å; L70-L264 HydrophobicContact CB-CD2 4.43Å; L70-L264 WeakPolarHBondContact O-CD2 3.43Å; L70-N267 HydrophobicContact CD2-CB 4.47Å; L70-I271 HydrophobicContact CD2-CD1 4.44Å; L70-V408 HydrophobicContact CD1-CG1 4.49Å; L70-V408 HydrophobicContact CD2-CG2 3.92Å; L70-V408 HydrophobicContact CG-CG2 3.86Å
71L83.2Confident80.3Confident68 Ų6842.5 Ų42.536%0.35622%0.224SC..THydrogen-bonded Turntrans-81.4-6177.6-64.2173000114.5S67 S68 S69 G73 T74 F75 L264S67-L71 WeakPolarHBondContact O-CG 3.31Å; S67-L71 PolarHBondContact O-N 2.89Å; S68-L71 CarbonylContact O-C 3.56Å; S68-L71 PolarHBondContact O-N 3.42Å; S69-L71 VanDerWaalsContact C-N 3.26Å; S69-L71 PolarHBondContact O-N 2.78Å; L71-G73 VanDerWaalsContact C-N 3.31Å; L71-G73 PolarHBondContact O-N 3.31Å; L71-T74 PolarHBondContact O-N 2.8Å; L71-T74 VanDerWaalsContact O-N 3.1Å; L71-T74 PolarHBondContact O-OG1 2.98Å; L71-F75 HydrophobicContact CB-CD2 4.31Å; L71-F75 HydrophobicContact CD2-CE2 4.19Å; L71-F75 PolarHBondContact O-N 3.11Å; L71-L264 HydrophobicContact CD2-CD1 3.98Å; L71-L264 HydrophobicContact CD2-CD2 4.12Å
72Y77.3Confident79.6Confident10 Ų1043.7 Ų43.74%0.03923%0.229CC..Iπ-helixtrans-55.5-45.7-178.1171-108.1000112.5S68 S69 T74 V76 A77 H82 T85 P121 N124 A125S68-Y72 PolarHBondContact O-N 3.06Å; S69-Y72 VanDerWaalsContact O-CB 3.28Å; S69-Y72 WeakPolarHBondContact O-CB 3.46Å; S69-Y72 PolarHBondContact O-N 3.38Å; Y72-T74 PolarHBondContact O-N 3.28Å; Y72-V76 HydrophobicContact CD2-CB 3.68Å; Y72-V76 HydrophobicContact CD2-CG1 3.75Å; Y72-V76 HydrophobicContact CD2-CG2 4.37Å; Y72-V76 HydrophobicContact CE2-CB 3.93Å; Y72-V76 HydrophobicContact CE2-CG1 3.56Å; Y72-V76 WeakPolarHBondContact O-CB 3.45Å; Y72-V76 PolarHBondContact O-N 2.92Å; Y72-V76 VanDerWaalsContact O-N 3.17Å; Y72-A77 HydrophobicContact CD1-CB 4.39Å; Y72-A77 HydrophobicContact CE1-CB 3.98Å; Y72-A77 PolarHBondContact O-N 3.1Å; Y72-H82 PolarHBondContact OH-CD2 3.21Å; Y72-T85 HydrophobicContact CE2-CG2 4.15Å; Y72-P121 HydrophobicContact CD2-CB 3.88Å; Y72-N124 VanDerWaalsContact CB-ND2 3.32Å; Y72-N124 WeakPolarHBondContact CB-ND2 3.4Å; Y72-N124 HydrophobicContact CD1-CB 3.49Å; Y72-N124 VanDerWaalsContact CD1-CB 3.49Å; Y72-N124 HydrophobicContact CD2-CB 4.17Å; Y72-N124 HydrophobicContact CE1-CB 3.86Å; Y72-N124 HydrophobicContact CE2-CB 4.48Å; Y72-N124 HydrophobicContact CG-CB 3.67Å; Y72-A125 HydrophobicContact CE2-CB 4.03Å
73G65.7Low79.1Confident12 Ų1244.6 Ų44.612%0.12423%0.233CC..Iπ-helixtrans-65.2-23.2-179.200000114.1L71 L263L71-G73 VanDerWaalsContact C-N 3.31Å; L71-G73 PolarHBondContact O-N 3.31Å; G73-L263 VanDerWaalsContact O-CD1 3.25Å; G73-L263 WeakPolarHBondContact O-CD1 3.44Å
74T65.3Low78.6Confident12 Ų1244.1 Ų44.17%0.07423%0.231CC..Iπ-helixtrans-90.3-45-17262.40000113.6L71 Y72 A260 L264L71-T74 PolarHBondContact O-N 2.8Å; L71-T74 VanDerWaalsContact O-N 3.1Å; L71-T74 PolarHBondContact O-OG1 2.98Å; Y72-T74 PolarHBondContact O-N 3.28Å; T74-A260 HydrophobicContact CG2-CB 3.91Å; T74-A260 WeakPolarHBondContact CG2-O 3.42Å; T74-L264 HydrophobicContact CG2-CD1 3.68Å; T74-L264 HydrophobicContact CG2-CD2 4.46Å; T74-L264 HydrophobicContact CG2-CG 3.54Å
75F64.2Low78.2Confident140 Ų14043 Ų4361%0.61422%0.224SC*.Iπ-helixtrans-103.7-47.8-175.5-64.3-72.3000112.1L71L71-F75 HydrophobicContact CB-CD2 4.31Å; L71-F75 HydrophobicContact CD2-CE2 4.19Å; L71-F75 PolarHBondContact O-N 3.11Å
76V63.2Low77.8Confident20 Ų2043 Ų4312%0.12122%0.224CC..Iπ-helixtrans-82.6-52.9-167.6-178.20000111Y72 R78 Q79 L80 T85 P121Y72-V76 HydrophobicContact CD2-CB 3.68Å; Y72-V76 HydrophobicContact CD2-CG1 3.75Å; Y72-V76 HydrophobicContact CD2-CG2 4.37Å; Y72-V76 HydrophobicContact CE2-CB 3.93Å; Y72-V76 HydrophobicContact CE2-CG1 3.56Å; Y72-V76 WeakPolarHBondContact O-CB 3.45Å; Y72-V76 PolarHBondContact O-N 2.92Å; Y72-V76 VanDerWaalsContact O-N 3.17Å; V76-R78 PolarHBondContact O-N 3.33Å; V76-Q79 PolarHBondContact O-N 2.99Å; V76-L80 HydrophobicContact CG1-CB 4.09Å; V76-L80 HydrophobicContact CG1-CD1 4.04Å; V76-L80 PolarHBondContact O-N 3.03Å; V76-T85 HydrophobicContact CG1-CG2 3.63Å; V76-T85 WeakPolarHBondContact CG1-OG1 3.44Å; V76-P121 HydrophobicContact CG1-CB 4.42Å; V76-P121 HydrophobicContact CG2-CB 4.22Å; V76-P121 HydrophobicContact CG2-CG 4.16Å
77A63.6Low77.7Confident21 Ų2144 Ų4417%0.17423%0.228CC..THydrogen-bonded Turntrans-62.2-20.5-172.800000114.8Y72Y72-A77 HydrophobicContact CD1-CB 4.39Å; Y72-A77 HydrophobicContact CE1-CB 3.98Å; Y72-A77 PolarHBondContact O-N 3.1Å
78R63.8Low77.5Confident99 Ų9944.7 Ų44.737%0.37423%0.227SC..THydrogen-bonded Turntrans-93.9-11.6-178.2-53.8-175.281.6-172.89.8114.3V76 E256 A258V76-R78 PolarHBondContact O-N 3.33Å; R78-E256 PolarHBondContact NE-O 3.46Å; R78-E256 PolarHBondContact NH2-O 3.05Å; R78-A258 PolarHBondContact NH1-O 3.5Å; R78-A258 PolarHBondContact NH2-O 2.83Å
79Q67.3Low77.2Confident174 Ų17444.4 Ų44.481%0.81323%0.225SC*.THydrogen-bonded Turntrans-130.7-29.2-173.9-64.9-173.2-7.600113.5V76V76-Q79 PolarHBondContact O-N 2.99Å
80L71.4Confident77.2Confident59 Ų5944.4 Ų44.431%0.30923%0.225SC..SBendtrans-113.7117.7-172-64.8169.5000110.3V76 V84 L88V76-L80 HydrophobicContact CG1-CB 4.09Å; V76-L80 HydrophobicContact CG1-CD1 4.04Å; V76-L80 PolarHBondContact O-N 3.03Å; L80-V84 HydrophobicContact CD2-CG1 3.88Å; L80-L88 HydrophobicContact CD1-CD2 4.1Å
81T77.6Confident77.2Confident59 Ų5946.4 Ų46.436%0.36224%0.238SC..  trans-59.4142.5171.969.10000109.9K83 V84 T85T81-K83 PolarHBondContact O-N 2.95Å; T81-V84 WeakPolarHBondContact O-CA 3.41Å; T81-V84 PolarHBondContact O-N 2.86Å; T81-T85 PolarHBondContact O-N 3.23Å
82H78.6Confident77.3Confident29 Ų2943.9 Ų43.913%0.13423%0.226CC..Hα-helixtrans-41.5-42.4-178.6-59.6100000114.5Y72 V84 T85 L86 Y129Y72-H82 PolarHBondContact OH-CD2 3.21Å; H82-V84 VanDerWaalsContact C-N 3.35Å; H82-V84 PolarHBondContact O-N 3.14Å; H82-T85 WeakPolarHBondContact O-CB 3.3Å; H82-T85 PolarHBondContact O-N 3.12Å; H82-L86 WeakPolarHBondContact O-CG 3.23Å; H82-L86 PolarHBondContact O-N 3.24Å; H82-L86 VanDerWaalsContact O-N 3.12Å; H82-Y129 HydrophobicContact CB-CD2 4.09Å
83K84.6Confident77.6Confident27 Ų2743.4 Ų43.412%0.11722%0.224CC..Hα-helixtrans-60.3-37.3177.6172160.8168.11500113.6T81 L87 T240 L241 L244 R246T81-K83 PolarHBondContact O-N 2.95Å; K83-L87 HydrophobicContact CG-CD1 4.31Å; K83-L87 WeakPolarHBondContact O-CD1 3.49Å; K83-L87 VanDerWaalsContact O-CG 3.3Å; K83-L87 WeakPolarHBondContact O-CG 3.45Å; K83-L87 PolarHBondContact O-N 2.96Å; K83-T240 WeakPolarHBondContact CE-O 3.32Å; K83-T240 HydrophobicContact CG-CG2 4.14Å; K83-T240 PolarHBondContact NZ-O 3.07Å; K83-L241 PolarHBondContact NZ-O 3.01Å; K83-L244 WeakPolarHBondContact CD-O 2.88Å; K83-L244 PolarHBondContact NZ-O 2.87Å; K83-R246 HydrophobicContact CD-CG 4.29Å
84V85.3Confident78.4Confident56 Ų5644.6 Ų44.634%0.33923%0.227SC..Hα-helixtrans-73.7-37.7176.5-178.70000110.6L80 T81 H82 L86 L87 L88L80-V84 HydrophobicContact CD2-CG1 3.88Å; T81-V84 WeakPolarHBondContact O-CA 3.41Å; T81-V84 PolarHBondContact O-N 2.86Å; H82-V84 VanDerWaalsContact C-N 3.35Å; H82-V84 PolarHBondContact O-N 3.14Å; V84-L86 VanDerWaalsContact C-N 3.33Å; V84-L86 PolarHBondContact O-N 2.72Å; V84-L87 PolarHBondContact O-N 3.36Å; V84-L88 WeakPolarHBondContact O-CB 3.33Å; V84-L88 PolarHBondContact O-N 3.43Å
85T86.2Confident78.9Confident0 Ų049.7 Ų49.70%025%0.253CS..Hα-helixtrans-60.6-40.3175.7-48.80000112.8Y72 V76 T81 H82 L88 T89 P121 A125Y72-T85 HydrophobicContact CE2-CG2 4.15Å; V76-T85 HydrophobicContact CG1-CG2 3.63Å; V76-T85 WeakPolarHBondContact CG1-OG1 3.44Å; T81-T85 PolarHBondContact O-N 3.23Å; H82-T85 WeakPolarHBondContact O-CB 3.3Å; H82-T85 PolarHBondContact O-N 3.12Å; T85-L88 PolarHBondContact O-N 3.27Å; T85-T89 PolarHBondContact O-OG1 3.36Å; T85-P121 HydrophobicContact CG2-CB 3.69Å; T85-P121 WeakPolarHBondContact CG2-O 3.48Å; T85-A125 HydrophobicContact CG2-CB 3.77Å
86L86.7Confident79.6Confident0 Ų043.3 Ų43.30%023%0.225CC..Hα-helixtrans-61.7-49.4174.6-64170.1000111L26 H82 V84 L88 T89 Y90 Y122 L126 L244L26-L86 HydrophobicContact CD1-CD1 3.6Å; L26-L86 HydrophobicContact CD1-CD2 4.33Å; H82-L86 WeakPolarHBondContact O-CG 3.23Å; H82-L86 PolarHBondContact O-N 3.24Å; H82-L86 VanDerWaalsContact O-N 3.12Å; V84-L86 VanDerWaalsContact C-N 3.33Å; V84-L86 PolarHBondContact O-N 2.72Å; L86-L88 VanDerWaalsContact C-N 3.32Å; L86-L88 PolarHBondContact O-N 3.11Å; L86-T89 PolarHBondContact O-N 2.93Å; L86-T89 VanDerWaalsContact O-N 3.13Å; L86-Y90 PolarHBondContact O-N 3.13Å; L86-Y122 HydrophobicContact CD2-CD2 3.51Å; L86-Y122 HydrophobicContact CD2-CE2 3.79Å; L86-Y122 HydrophobicContact CD2-CG 4.39Å; L86-L126 HydrophobicContact CD2-CB 4.14Å; L86-L126 HydrophobicContact CD2-CD1 4.45Å; L86-L244 HydrophobicContact CD1-CD2 3.87Å
87L89.2Confident80.3Confident25 Ų2542.5 Ų42.513%0.13122%0.22CC..Hα-helixtrans-61.6-37.5178.3-67.7166.2000112.9K83 V84 T89 Y90 V91 V237 T240 L241K83-L87 HydrophobicContact CG-CD1 4.31Å; K83-L87 WeakPolarHBondContact O-CD1 3.49Å; K83-L87 VanDerWaalsContact O-CG 3.3Å; K83-L87 WeakPolarHBondContact O-CG 3.45Å; K83-L87 PolarHBondContact O-N 2.96Å; V84-L87 PolarHBondContact O-N 3.36Å; L87-T89 PolarHBondContact O-N 3.05Å; L87-T89 VanDerWaalsContact O-N 3.12Å; L87-Y90 HydrophobicContact CD2-CD2 4.38Å; L87-Y90 PolarHBondContact O-N 3.35Å; L87-V91 PolarHBondContact O-N 3.4Å; L87-V91 VanDerWaalsContact O-N 3.14Å; L87-V237 HydrophobicContact CD2-CB 4.41Å; L87-V237 HydrophobicContact CD2-CG1 4.07Å; L87-V237 HydrophobicContact CD2-CG2 4.46Å; L87-T240 HydrophobicContact CD1-CG2 4.21Å; L87-T240 HydrophobicContact CD2-CG2 3.69Å; L87-T240 HydrophobicContact CG-CG2 3.7Å; L87-L241 HydrophobicContact CD1-CD2 3.59Å; L87-L241 HydrophobicContact CD1-CG 4.12Å; L87-L241 HydrophobicContact CD2-CD2 4.33Å; L87-L241 HydrophobicContact CD2-CG 3.95Å
88L87.5Confident80.8Confident78 Ų7843.2 Ų43.241%0.40822%0.223SC..Hα-helixtrans-62.2-15.6177.4-176.259.7000113.1L80 V84 T85 L86 P92 T118L80-L88 HydrophobicContact CD1-CD2 4.1Å; V84-L88 WeakPolarHBondContact O-CB 3.33Å; V84-L88 PolarHBondContact O-N 3.43Å; T85-L88 PolarHBondContact O-N 3.27Å; L86-L88 VanDerWaalsContact C-N 3.32Å; L86-L88 PolarHBondContact O-N 3.11Å; L88-P92 WeakPolarHBondContact O-CD 3.22Å; L88-P92 WeakPolarHBondContact O-CG 3.24Å; L88-T118 HydrophobicContact CG-CG2 4.11Å; L88-T118 WeakPolarHBondContact O-CG2 3.42Å
89T86.6Confident81.2Confident1 Ų138.5 Ų38.51%0.00621%0.206CC..Hα-helixtrans-97.7-34.9175.9-56.30000112.4Y33 T85 L86 L87 F93 T118 Y122Y33-T89 HydrophobicContact CE2-CG2 4.46Å; T85-T89 PolarHBondContact O-OG1 3.36Å; L86-T89 PolarHBondContact O-N 2.93Å; L86-T89 VanDerWaalsContact O-N 3.13Å; L87-T89 PolarHBondContact O-N 3.05Å; L87-T89 VanDerWaalsContact O-N 3.12Å; T89-F93 PolarHBondContact O-N 3.28Å; T89-T118 WeakPolarHBondContact OG1-CB 2.92Å; T89-T118 PolarHBondContact OG1-O 3.24Å; T89-Y122 HydrophobicContact CG2-CD2 4.44Å; T89-Y122 HydrophobicContact CG2-CG 4.15Å; T89-Y122 VanDerWaalsContact OG1-CB 3.28Å; T89-Y122 WeakPolarHBondContact OG1-CB 3.33Å
90Y89Confident81.5Confident0 Ų030.2 Ų30.20%017%0.167CC..Hα-helixtrans-67.4-37.2176.8-55.8-25.7000112.3S29 Y33 L86 L87 F93 M94 Y122 I233 S236 V237S29-Y90 WeakPolarHBondContact OG-CE2 3.37Å; S29-Y90 PolarHBondContact OG-OH 2.87Å; Y33-Y90 HydrophobicContact CD1-CD1 4.31Å; Y33-Y90 AromaticContact CD1-CE1 3.88Å; Y33-Y90 HydrophobicContact CD1-CE1 3.88Å; Y33-Y90 AromaticContact CD2-CD1 3.57Å; Y33-Y90 HydrophobicContact CD2-CD1 3.57Å; Y33-Y90 AromaticContact CD2-CE1 3.95Å; Y33-Y90 HydrophobicContact CD2-CE1 3.95Å; Y33-Y90 HydrophobicContact CE2-CD1 4.12Å; Y33-Y90 AromaticContact CG-CD1 3.68Å; Y33-Y90 HydrophobicContact CG-CD1 3.68Å; Y33-Y90 AromaticContact CG-CE1 3.54Å; Y33-Y90 HydrophobicContact CG-CE1 3.54Å; L86-Y90 PolarHBondContact O-N 3.13Å; L87-Y90 HydrophobicContact CD2-CD2 4.38Å; L87-Y90 PolarHBondContact O-N 3.35Å; Y90-F93 PolarHBondContact O-N 3.47Å; Y90-M94 PolarHBondContact O-N 3.11Å; Y90-Y122 HydrophobicContact CE1-CD2 4.13Å; Y90-Y122 AromaticContact CE1-CE2 3.61Å; Y90-Y122 HydrophobicContact CE1-CE2 3.61Å; Y90-I233 WeakPolarHBondContact O-CG2 3.49Å; Y90-S236 VanDerWaalsContact CE2-OG 3.32Å; Y90-S236 WeakPolarHBondContact CE2-OG 3.42Å; Y90-V237 HydrophobicContact CD2-CG2 3.99Å; Y90-V237 HydrophobicContact CG-CG2 4.26Å
91V86Confident81.4Confident84 Ų8430.1 Ų30.151%0.50917%0.166SC..Hα-helixtrans-67-49-177.8172.60000112.7L87 F93 M94L87-V91 PolarHBondContact O-N 3.4Å; L87-V91 VanDerWaalsContact O-N 3.14Å; V91-F93 VanDerWaalsContact C-N 3.27Å; V91-F93 PolarHBondContact O-N 3.5Å; V91-M94 VanDerWaalsContact O-CB 3.26Å; V91-M94 WeakPolarHBondContact O-CB 3.48Å; V91-M94 PolarHBondContact O-N 3.29Å
92P83.7Confident81Confident16 Ų1634.7 Ų34.710%0.10418%0.178CC..Hα-helixtrans-68.5-23.7176.3-21.534.7000114L88 M94 L95 F96 V114 T118L88-P92 WeakPolarHBondContact O-CD 3.22Å; L88-P92 WeakPolarHBondContact O-CG 3.24Å; P92-M94 PolarHBondContact O-N 2.86Å; P92-L95 WeakPolarHBondContact O-CA 3.33Å; P92-L95 WeakPolarHBondContact O-CB 3.3Å; P92-L95 PolarHBondContact O-N 3.43Å; P92-F96 PolarHBondContact O-N 3.4Å; P92-V114 HydrophobicContact CB-CG1 3.72Å; P92-V114 HydrophobicContact CG-CG1 4.27Å; P92-T118 HydrophobicContact CG-CG2 4.25Å
93F83.8Confident80.7Confident0 Ų035.6 Ų35.60%018%0.18CC..Hα-helixtrans-64.1-28.8173.4-169.9-102.3000112.3Y33 C36 I37 L40 T89 Y90 V91 L95 F96 I115 I233Y33-F93 HydrophobicContact CD2-CD1 4.3Å; Y33-F93 HydrophobicContact CD2-CG 4.44Å; Y33-F93 HydrophobicContact CE2-CB 4.02Å; Y33-F93 HydrophobicContact CE2-CD1 4.16Å; Y33-F93 HydrophobicContact CE2-CD2 4.3Å; Y33-F93 AromaticContact CE2-CG 3.87Å; Y33-F93 HydrophobicContact CE2-CG 3.87Å; C36-F93 HydrophobicContact CB-CE1 3.58Å; C36-F93 HydrophobicContact CB-CZ 4.26Å; I37-F93 HydrophobicContact CB-CD2 4.42Å; I37-F93 HydrophobicContact CB-CE1 4.33Å; I37-F93 HydrophobicContact CB-CE2 3.66Å; I37-F93 HydrophobicContact CB-CZ 3.62Å; I37-F93 HydrophobicContact CD1-CD2 4.06Å; I37-F93 HydrophobicContact CD1-CE2 3.81Å; I37-F93 HydrophobicContact CG1-CD2 4.36Å; I37-F93 HydrophobicContact CG1-CE2 3.62Å; I37-F93 HydrophobicContact CG1-CZ 4.07Å; L40-F93 HydrophobicContact CD2-CE2 4.15Å; L40-F93 HydrophobicContact CD2-CZ 3.68Å; T89-F93 PolarHBondContact O-N 3.28Å; Y90-F93 PolarHBondContact O-N 3.47Å; V91-F93 VanDerWaalsContact C-N 3.27Å; V91-F93 PolarHBondContact O-N 3.5Å; F93-L95 VanDerWaalsContact C-N 3.31Å; F93-L95 PolarHBondContact O-N 3.34Å; F93-F96 HydrophobicContact CD2-CD1 4.41Å; F93-F96 AromaticContact CE2-CD1 3.93Å; F93-F96 HydrophobicContact CE2-CD1 3.93Å; F93-F96 HydrophobicContact CE2-CE1 4.47Å; F93-F96 PolarHBondContact O-N 3.13Å; F93-I115 HydrophobicContact CD2-CD1 3.61Å; F93-I115 HydrophobicContact CD2-CG1 4.31Å; F93-I115 HydrophobicContact CE2-CD1 4.16Å; F93-I233 HydrophobicContact CD1-CD1 3.43Å; F93-I233 VanDerWaalsContact CD1-CD1 3.43Å; F93-I233 HydrophobicContact CD1-CG1 3.91Å; F93-I233 HydrophobicContact CE1-CD1 3.68Å; F93-I233 HydrophobicContact CE1-CG1 4.24Å
94M82.2Confident80.3Confident36 Ų3639 Ų3918%0.17720%0.195CC..Hα-helixtrans-60.1-38.6167.2-62-73-147.400112.5Y90 V91 P92 F96 P98 F230 I233Y90-M94 PolarHBondContact O-N 3.11Å; V91-M94 VanDerWaalsContact O-CB 3.26Å; V91-M94 WeakPolarHBondContact O-CB 3.48Å; V91-M94 PolarHBondContact O-N 3.29Å; P92-M94 PolarHBondContact O-N 2.86Å; M94-F96 VanDerWaalsContact C-N 3.29Å; M94-F96 PolarHBondContact O-N 3.38Å; M94-P98 WeakPolarHBondContact O-CD 3.38Å; M94-F230 HydrophobicContact CB-CE1 3.9Å; M94-F230 HydrophobicContact CB-CZ 4.04Å; M94-F230 HydrophobicContact CE-CD1 4.07Å; M94-F230 HydrophobicContact CG-CE1 4.31Å; M94-F230 VanDerWaalsContact O-CZ 3.24Å; M94-F230 WeakPolarHBondContact O-CZ 3.39Å; M94-F230 HydrophobicContact SD-CB 4.36Å; M94-F230 HydrophobicContact SD-CD1 3.46Å; M94-F230 WeakPolarHBondContact SD-CD1 3.09Å; M94-F230 HydrophobicContact SD-CD2 4.39Å; M94-F230 HydrophobicContact SD-CE1 3.72Å; M94-F230 HydrophobicContact SD-CG 3.83Å; M94-F230 HydrophobicContact SD-CZ 4.29Å; M94-I233 HydrophobicContact CE-CB 3.73Å; M94-I233 HydrophobicContact CE-CG2 3.8Å; M94-I233 HydrophobicContact CG-CG2 3.96Å; M94-I233 HydrophobicContact SD-CB 3.61Å; M94-I233 HydrophobicContact SD-CD1 3.74Å; M94-I233 HydrophobicContact SD-CG1 4.33Å; M94-I233 HydrophobicContact SD-CG2 3.7Å
95L77.4Confident80.1Confident120 Ų12041 Ų4163%0.62820%0.2SC*.Hα-helixtrans-72.9-22.5-178.1-55.8177.2000112.7P92 F93 P98P92-L95 WeakPolarHBondContact O-CA 3.33Å; P92-L95 WeakPolarHBondContact O-CB 3.3Å; P92-L95 PolarHBondContact O-N 3.43Å; F93-L95 VanDerWaalsContact C-N 3.31Å; F93-L95 PolarHBondContact O-N 3.34Å; L95-P98 WeakPolarHBondContact O-CD 3.43Å
96F78.1Confident80Confident6 Ų649 Ų493%0.02623%0.232CC..Hα-helixtrans-78.3-29178.1180-108.1000113.7L40 L44 P92 F93 M94 G99 V100 L108 A111 A112 I115L40-F96 HydrophobicContact CD2-CD1 3.63Å; L40-F96 HydrophobicContact CD2-CE1 3.68Å; L40-F96 HydrophobicContact CG-CE1 4.23Å; L44-F96 HydrophobicContact CD2-CE1 4.45Å; L44-F96 HydrophobicContact CD2-CZ 3.77Å; P92-F96 PolarHBondContact O-N 3.4Å; F93-F96 HydrophobicContact CD2-CD1 4.41Å; F93-F96 AromaticContact CE2-CD1 3.93Å; F93-F96 HydrophobicContact CE2-CD1 3.93Å; F93-F96 HydrophobicContact CE2-CE1 4.47Å; F93-F96 PolarHBondContact O-N 3.13Å; M94-F96 VanDerWaalsContact C-N 3.29Å; M94-F96 PolarHBondContact O-N 3.38Å; F96-G99 CarbonylContact O-C 3.44Å; F96-G99 WeakPolarHBondContact O-CA 3.11Å; F96-G99 PolarHBondContact O-N 3.12Å; F96-V100 HydrophobicContact CD1-CG2 3.87Å; F96-V100 HydrophobicContact CD2-CG2 4.48Å; F96-V100 HydrophobicContact CE1-CG2 3.45Å; F96-V100 VanDerWaalsContact CE1-CG2 3.45Å; F96-V100 HydrophobicContact CE2-CG2 4.13Å; F96-V100 HydrophobicContact CG-CG2 4.37Å; F96-V100 HydrophobicContact CZ-CG2 3.6Å; F96-V100 PolarHBondContact O-N 3.45Å; F96-L108 HydrophobicContact CE2-CD1 3.76Å; F96-L108 HydrophobicContact CZ-CD1 4.18Å; F96-A111 HydrophobicContact CB-CB 4.34Å; F96-A111 HydrophobicContact CD2-CB 3.73Å; F96-A112 HydrophobicContact CE2-CB 4.36Å; F96-I115 HydrophobicContact CB-CD1 3.33Å; F96-I115 HydrophobicContact CB-CG1 4.27Å; F96-I115 HydrophobicContact CD1-CD1 3.58Å; F96-I115 HydrophobicContact CD2-CD1 3.61Å; F96-I115 HydrophobicContact CE1-CD1 4.2Å; F96-I115 HydrophobicContact CE2-CD1 4.24Å; F96-I115 HydrophobicContact CG-CD1 3.24Å
97I78.8Confident79.9Confident2 Ų251.4 Ų51.41%0.0125%0.246CC..Hα-helixtrans-56.7-50.1176.9-70.5162.2000111.6L40 G99 V100 I101 F226 F230 I233L40-I97 HydrophobicContact CD2-CG1 4.18Å; I97-G99 VanDerWaalsContact C-N 3.28Å; I97-G99 PolarHBondContact O-N 3.42Å; I97-V100 PolarHBondContact O-N 2.85Å; I97-I101 HydrophobicContact CG2-CD1 3.65Å; I97-I101 HydrophobicContact CG2-CG1 4.48Å; I97-I101 WeakPolarHBondContact O-CG1 3.18Å; I97-I101 PolarHBondContact O-N 2.9Å; I97-F226 HydrophobicContact CG2-CD2 4.07Å; I97-F230 HydrophobicContact CB-CE2 3.86Å; I97-F230 HydrophobicContact CD1-CD2 3.92Å; I97-F230 HydrophobicContact CD1-CE2 3.89Å; I97-F230 HydrophobicContact CG2-CD2 4.28Å; I97-F230 HydrophobicContact CG2-CE2 3.81Å; I97-I233 HydrophobicContact CD1-CD1 3.39Å
98P72.9Confident79.7Confident37 Ų3750.3 Ų50.324%0.2424%0.24CC..Hα-helixtrans-52.6-42.3168-27.433000113.9M94 L95 V100 I101 Y102 F226M94-P98 WeakPolarHBondContact O-CD 3.38Å; L95-P98 WeakPolarHBondContact O-CD 3.43Å; P98-V100 VanDerWaalsContact C-N 3.34Å; P98-V100 PolarHBondContact O-N 3.41Å; P98-I101 PolarHBondContact O-N 3Å; P98-Y102 HydrophobicContact CB-CD2 4.23Å; P98-Y102 HydrophobicContact CB-CE2 4.27Å; P98-Y102 WeakPolarHBondContact O-CD2 3.47Å; P98-Y102 PolarHBondContact O-N 3.39Å; P98-F226 HydrophobicContact CG-CE2 4.29Å
99G72.2Confident79.7Confident0 Ų049 Ų490%023%0.234CC..Hα-helixtrans-62.9-36.1-17900000114.1F96 I97F96-G99 CarbonylContact O-C 3.44Å; F96-G99 WeakPolarHBondContact O-CA 3.11Å; F96-G99 PolarHBondContact O-N 3.12Å; I97-G99 VanDerWaalsContact C-N 3.28Å; I97-G99 PolarHBondContact O-N 3.42Å
100V73.6Confident79.9Confident0 Ų052 Ų520%025%0.253CS..Hα-helixtrans-72.7-46.9172.2179.50000111.1L40 L44 F96 I97 P98 Y103 L108 W214L40-V100 HydrophobicContact CD1-CB 4.16Å; L40-V100 HydrophobicContact CD1-CG1 3.82Å; L40-V100 HydrophobicContact CD1-CG2 4.21Å; L40-V100 HydrophobicContact CD2-CG2 4.21Å; L40-V100 HydrophobicContact CG-CG2 4.22Å; L44-V100 HydrophobicContact CD1-CG1 4.34Å; L44-V100 HydrophobicContact CD2-CG2 4.09Å; F96-V100 HydrophobicContact CD1-CG2 3.87Å; F96-V100 HydrophobicContact CD2-CG2 4.48Å; F96-V100 HydrophobicContact CE1-CG2 3.45Å; F96-V100 VanDerWaalsContact CE1-CG2 3.45Å; F96-V100 HydrophobicContact CE2-CG2 4.13Å; F96-V100 HydrophobicContact CG-CG2 4.37Å; F96-V100 HydrophobicContact CZ-CG2 3.6Å; F96-V100 PolarHBondContact O-N 3.45Å; I97-V100 PolarHBondContact O-N 2.85Å; P98-V100 VanDerWaalsContact C-N 3.34Å; P98-V100 PolarHBondContact O-N 3.41Å; V100-Y103 PolarHBondContact O-N 3.22Å; V100-L108 HydrophobicContact CG2-CD1 3.96Å; V100-W214 HydrophobicContact CG1-CD2 4.31Å; V100-W214 HydrophobicContact CG1-CH2 4.28Å; V100-W214 HydrophobicContact CG1-CZ2 4.04Å
101I68.8Low79.9Confident56 Ų5652.8 Ų52.829%0.28726%0.259SS..Hα-helixtrans-62.7-46.3-176.4-68168.3000112.1I97 P98 Y103 P222 F226I97-I101 HydrophobicContact CG2-CD1 3.65Å; I97-I101 HydrophobicContact CG2-CG1 4.48Å; I97-I101 WeakPolarHBondContact O-CG1 3.18Å; I97-I101 PolarHBondContact O-N 2.9Å; P98-I101 PolarHBondContact O-N 3Å; I101-Y103 PolarHBondContact O-N 3.25Å; I101-P222 HydrophobicContact CG2-CB 4.41Å; I101-F226 HydrophobicContact CD1-CB 4.4Å; I101-F226 HydrophobicContact CD1-CD2 4.09Å
102Y70.4Confident80.1Confident156 Ų15648.8 Ų48.861%0.61224%0.236SC*.THydrogen-bonded Turntrans-74.5-14.2179.8-72.2-61.3000113.8P98 K104P98-Y102 HydrophobicContact CB-CD2 4.23Å; P98-Y102 HydrophobicContact CB-CE2 4.27Å; P98-Y102 WeakPolarHBondContact O-CD2 3.47Å; P98-Y102 PolarHBondContact O-N 3.39Å; Y102-K104 VanDerWaalsContact C-N 3.31Å; Y102-K104 WeakPolarHBondContact O-CG 3.18Å; Y102-K104 PolarHBondContact O-N 3.16Å
103Y71.5Confident80.5Confident47 Ų4751.1 Ų51.118%0.18425%0.246CC..THydrogen-bonded Turntrans42.253179.7-159.5-93.5000113.6L44 D49 V100 I101 L108L44-Y103 HydrophobicContact CD1-CE2 4.3Å; D49-Y103 PolarHBondContact OD1-OH 2.86Å; D49-Y103 PolarHBondContact OD2-OH 3.43Å; D49-Y103 VanDerWaalsContact OD2-OH 3.1Å; V100-Y103 PolarHBondContact O-N 3.22Å; I101-Y103 PolarHBondContact O-N 3.25Å; Y103-L108 HydrophobicContact CE2-CD2 4.22Å
104K77.3Confident81Confident98 Ų9854.2 Ų54.243%0.42627%0.265SS..  trans-110.1124.8175.4-63.1-57.4-178.3-1750109.9Y102 Y106 V107 L108Y102-K104 VanDerWaalsContact C-N 3.31Å; Y102-K104 WeakPolarHBondContact O-CG 3.18Å; Y102-K104 PolarHBondContact O-N 3.16Å; K104-Y106 HydrophobicContact CB-CD1 4.34Å; K104-Y106 HydrophobicContact CB-CD2 4.29Å; K104-Y106 HydrophobicContact CB-CE1 4Å; K104-Y106 HydrophobicContact CB-CE2 3.92Å; K104-Y106 HydrophobicContact CB-CG 4.48Å; K104-Y106 HydrophobicContact CD-CE1 4.34Å; K104-Y106 HydrophobicContact CG-CE1 4.3Å; K104-Y106 HydrophobicContact CG-CE2 4.25Å; K104-Y106 PolarHBondContact O-N 2.87Å; K104-Y106 VanDerWaalsContact O-N 3.12Å; K104-V107 HydrophobicContact CB-CB 4.4Å; K104-V107 HydrophobicContact CB-CG2 3.95Å; K104-V107 PolarHBondContact O-N 2.75Å; K104-L108 PolarHBondContact O-N 2.9Å
105H80.7Confident81.4Confident98 Ų9852.5 Ų52.545%0.45426%0.257SS..Hα-helixtrans-41.3-49.2175.5-53.584.5000113.3V53 V107 L109V53-H105 VanDerWaalsContact CG2-CD2 3.5Å; V53-H105 WeakPolarHBondContact CG2-CD2 3.44Å; H105-V107 VanDerWaalsContact C-N 3.28Å; H105-V107 PolarHBondContact O-N 3.01Å; H105-L109 WeakPolarHBondContact O-CB 3.42Å; H105-L109 PolarHBondContact O-N 3.29Å; H105-L109 VanDerWaalsContact O-N 3.09Å
106Y83.2Confident82.1Confident170 Ų17046.8 Ų46.867%0.66723%0.227SC*.Hα-helixtrans-75.9-6.1-177.158.1-104.9000115K104 P110K104-Y106 HydrophobicContact CB-CD1 4.34Å; K104-Y106 HydrophobicContact CB-CD2 4.29Å; K104-Y106 HydrophobicContact CB-CE1 4Å; K104-Y106 HydrophobicContact CB-CE2 3.92Å; K104-Y106 HydrophobicContact CB-CG 4.48Å; K104-Y106 HydrophobicContact CD-CE1 4.34Å; K104-Y106 HydrophobicContact CG-CE1 4.3Å; K104-Y106 HydrophobicContact CG-CE2 4.25Å; K104-Y106 PolarHBondContact O-N 2.87Å; K104-Y106 VanDerWaalsContact O-N 3.12Å; Y106-P110 WeakPolarHBondContact O-CD 3.32Å; Y106-P110 WeakPolarHBondContact O-CG 3.31Å
107V85.9Confident82.8Confident50 Ų5051.1 Ų51.130%0.30325%0.25SC..Hα-helixtrans-105.1-44.4170.8-170.20000110.1K104 H105 A111K104-V107 HydrophobicContact CB-CB 4.4Å; K104-V107 HydrophobicContact CB-CG2 3.95Å; K104-V107 PolarHBondContact O-N 2.75Å; H105-V107 VanDerWaalsContact C-N 3.28Å; H105-V107 PolarHBondContact O-N 3.01Å; V107-A111 VanDerWaalsContact O-CB 3.23Å; V107-A111 WeakPolarHBondContact O-CB 3.34Å; V107-A111 PolarHBondContact O-N 2.89Å
108L84Confident83.3Confident1 Ų151.7 Ų51.71%0.00525%0.253CS..Hα-helixtrans-64.3-44.8-177.4-173.266.5000112.4L44 V53 A57 F96 V100 Y103 K104 A112L44-L108 HydrophobicContact CD1-CD2 4.26Å; L44-L108 HydrophobicContact CD2-CD1 4.2Å; V53-L108 HydrophobicContact CG1-CD2 4.49Å; A57-L108 HydrophobicContact CB-CD2 4.13Å; A57-L108 HydrophobicContact CB-CG 4.02Å; F96-L108 HydrophobicContact CE2-CD1 3.76Å; F96-L108 HydrophobicContact CZ-CD1 4.18Å; V100-L108 HydrophobicContact CG2-CD1 3.96Å; Y103-L108 HydrophobicContact CE2-CD2 4.22Å; K104-L108 PolarHBondContact O-N 2.9Å; L108-A112 VanDerWaalsContact O-CB 3.24Å; L108-A112 WeakPolarHBondContact O-CB 3.44Å; L108-A112 PolarHBondContact O-N 3.21Å
109L88.4Confident84.2Confident51 Ų5150.1 Ų50.127%0.26724%0.243SC..Hα-helixtrans-67-48.8-178.7-70.9167.7000112.6I56 A57 L60 H105 A111 A112 I113I56-L109 HydrophobicContact CG2-CD2 4.24Å; A57-L109 HydrophobicContact CB-CD2 3.89Å; L60-L109 HydrophobicContact CD2-CD2 4.28Å; H105-L109 WeakPolarHBondContact O-CB 3.42Å; H105-L109 PolarHBondContact O-N 3.29Å; H105-L109 VanDerWaalsContact O-N 3.09Å; L109-A111 PolarHBondContact O-N 3.2Å; L109-A112 PolarHBondContact O-N 3.12Å; L109-I113 WeakPolarHBondContact O-CG1 3.46Å; L109-I113 PolarHBondContact O-N 3.34Å; L109-I113 VanDerWaalsContact O-N 3.1Å
110P90.7Very high85Confident64 Ų6450.1 Ų50.142%0.41624%0.243SC..Hα-helixtrans-61-42.4173.4-27.137.8000113.4Y106 A112 I113 V114Y106-P110 WeakPolarHBondContact O-CD 3.32Å; Y106-P110 WeakPolarHBondContact O-CG 3.31Å; P110-A112 VanDerWaalsContact C-N 3.32Å; P110-A112 PolarHBondContact O-N 3.34Å; P110-I113 WeakPolarHBondContact O-CB 3.27Å; P110-I113 PolarHBondContact O-N 2.92Å; P110-V114 WeakPolarHBondContact O-CG2 3.48Å; P110-V114 PolarHBondContact O-N 3.06Å
111A88.6Confident85.7Confident16 Ų1650.5 Ų50.513%0.13225%0.245CC..Hα-helixtrans-65.9-34.8179.900000112.4F96 V107 L109 V114 I115F96-A111 HydrophobicContact CB-CB 4.34Å; F96-A111 HydrophobicContact CD2-CB 3.73Å; V107-A111 VanDerWaalsContact O-CB 3.23Å; V107-A111 WeakPolarHBondContact O-CB 3.34Å; V107-A111 PolarHBondContact O-N 2.89Å; L109-A111 PolarHBondContact O-N 3.2Å; A111-V114 PolarHBondContact O-N 3.03Å; A111-I115 PolarHBondContact O-N 3.05Å
112A90.1Very high86.7Confident1 Ų147.9 Ų47.91%0.00823%0.232CC..Hα-helixtrans-63.9-41.2171.500000112.8A57 L61 F96 L108 L109 P110 G116A57-A112 HydrophobicContact CB-CB 4.11Å; A57-A112 WeakPolarHBondContact O-CB 3.28Å; L61-A112 HydrophobicContact CB-CB 4.21Å; F96-A112 HydrophobicContact CE2-CB 4.36Å; L108-A112 VanDerWaalsContact O-CB 3.24Å; L108-A112 WeakPolarHBondContact O-CB 3.44Å; L108-A112 PolarHBondContact O-N 3.21Å; L109-A112 PolarHBondContact O-N 3.12Å; P110-A112 VanDerWaalsContact C-N 3.32Å; P110-A112 PolarHBondContact O-N 3.34Å; A112-G116 PolarHBondContact O-N 3.2Å
113I92.9Very high87.6Confident64 Ų6442.4 Ų42.433%0.32821%0.211SC..Hα-helixtrans-61.9-46.8173.2-64.9164.4000110.5L60 V64 L109 P110 I115 G116 L117L60-I113 HydrophobicContact CD2-CD1 3.93Å; L60-I113 HydrophobicContact CD2-CG1 3.59Å; L60-I113 HydrophobicContact CG-CG1 3.95Å; V64-I113 HydrophobicContact CG1-CG2 4.45Å; L109-I113 WeakPolarHBondContact O-CG1 3.46Å; L109-I113 PolarHBondContact O-N 3.34Å; L109-I113 VanDerWaalsContact O-N 3.1Å; P110-I113 WeakPolarHBondContact O-CB 3.27Å; P110-I113 PolarHBondContact O-N 2.92Å; I113-I115 PolarHBondContact O-N 3.46Å; I113-G116 PolarHBondContact O-N 3.43Å; I113-G116 VanDerWaalsContact O-N 3.12Å; I113-L117 HydrophobicContact CG2-CD1 4.17Å; I113-L117 HydrophobicContact CG2-CG 4.39Å; I113-L117 WeakPolarHBondContact O-CG 3.46Å; I113-L117 PolarHBondContact O-N 3.34Å
114V92.2Very high88.4Confident65 Ų6540.6 Ų40.639%0.39421%0.205SC..Hα-helixtrans-64.3-41.6-177.7177.80000111.6P92 P110 A111 L117 T118P92-V114 HydrophobicContact CB-CG1 3.72Å; P92-V114 HydrophobicContact CG-CG1 4.27Å; P110-V114 WeakPolarHBondContact O-CG2 3.48Å; P110-V114 PolarHBondContact O-N 3.06Å; A111-V114 PolarHBondContact O-N 3.03Å; V114-L117 PolarHBondContact O-N 2.88Å; V114-T118 PolarHBondContact O-N 3.38Å; V114-T118 PolarHBondContact O-OG1 2.79Å
115I91.1Very high88.8Confident1 Ų135.9 Ų35.91%0.00518%0.184CC..Hα-helixtrans-60.9-47.2170.4-70.4166.3000110.5L61 F93 F96 A111 I113 L117 T118 Q119L61-I115 HydrophobicContact CD1-CB 4.04Å; L61-I115 HydrophobicContact CD1-CD1 4.35Å; L61-I115 HydrophobicContact CD1-CG2 3.83Å; L61-I115 HydrophobicContact CD2-CG2 4.29Å; L61-I115 HydrophobicContact CG-CB 4.32Å; L61-I115 HydrophobicContact CG-CG2 4.04Å; F93-I115 HydrophobicContact CD2-CD1 3.61Å; F93-I115 HydrophobicContact CD2-CG1 4.31Å; F93-I115 HydrophobicContact CE2-CD1 4.16Å; F96-I115 HydrophobicContact CB-CD1 3.33Å; F96-I115 HydrophobicContact CB-CG1 4.27Å; F96-I115 HydrophobicContact CD1-CD1 3.58Å; F96-I115 HydrophobicContact CD2-CD1 3.61Å; F96-I115 HydrophobicContact CE1-CD1 4.2Å; F96-I115 HydrophobicContact CE2-CD1 4.24Å; F96-I115 HydrophobicContact CG-CD1 3.24Å; A111-I115 PolarHBondContact O-N 3.05Å; I113-I115 PolarHBondContact O-N 3.46Å; I115-L117 PolarHBondContact O-N 3.29Å; I115-T118 PolarHBondContact O-N 3.29Å; I115-T118 PolarHBondContact O-OG1 2.92Å; I115-Q119 HydrophobicContact CG2-CB 4.1Å; I115-Q119 WeakPolarHBondContact O-CB 3.38Å; I115-Q119 PolarHBondContact O-N 3.07Å
116G92.6Very high89.3Confident0 Ų031.2 Ų31.20%016%0.163CC..Hα-helixtrans-55-39.717900000112.5L61 V64 S65 S68 A112 I113 T118L61-G116 WeakPolarHBondContact O-CA 3.47Å; V64-G116 CarbonylContact C-O 3.57Å; S65-G116 WeakPolarHBondContact CA-O 3.41Å; S65-G116 PolarHBondContact N-O 3.32Å; S68-G116 PolarHBondContact OG-O 3.28Å; A112-G116 PolarHBondContact O-N 3.2Å; I113-G116 PolarHBondContact O-N 3.43Å; I113-G116 VanDerWaalsContact O-N 3.12Å; G116-T118 VanDerWaalsContact C-N 3.28Å; G116-T118 PolarHBondContact O-N 3.07Å
117L92Very high89.5Confident97 Ų9723.9 Ų23.951%0.50813%0.134SC..Hα-helixtrans-65.1-28.3178-72.6173.8000113.3V64 S68 I113 V114 I115 P121V64-L117 HydrophobicContact CG1-CB 4.44Å; V64-L117 HydrophobicContact CG1-CD2 3.63Å; V64-L117 HydrophobicContact CG1-CG 3.69Å; S68-L117 WeakPolarHBondContact CB-O 3.42Å; I113-L117 HydrophobicContact CG2-CD1 4.17Å; I113-L117 HydrophobicContact CG2-CG 4.39Å; I113-L117 WeakPolarHBondContact O-CG 3.46Å; I113-L117 PolarHBondContact O-N 3.34Å; V114-L117 PolarHBondContact O-N 2.88Å; I115-L117 PolarHBondContact O-N 3.29Å; L117-P121 WeakPolarHBondContact O-CD 3.15Å; L117-P121 WeakPolarHBondContact O-CG 3.5Å
118T90.2Very high89.5Confident14 Ų1421.8 Ų21.89%0.08612%0.122CC..Hα-helixtrans-100.9-33.1-177.458.90000113.5L88 T89 P92 V114 I115 G116 G120 P121 Y122L88-T118 HydrophobicContact CG-CG2 4.11Å; L88-T118 WeakPolarHBondContact O-CG2 3.42Å; T89-T118 WeakPolarHBondContact OG1-CB 2.92Å; T89-T118 PolarHBondContact OG1-O 3.24Å; P92-T118 HydrophobicContact CG-CG2 4.25Å; V114-T118 PolarHBondContact O-N 3.38Å; V114-T118 PolarHBondContact O-OG1 2.79Å; I115-T118 PolarHBondContact O-N 3.29Å; I115-T118 PolarHBondContact O-OG1 2.92Å; G116-T118 VanDerWaalsContact C-N 3.28Å; G116-T118 PolarHBondContact O-N 3.07Å; T118-G120 PolarHBondContact O-N 3.47Å; T118-P121 WeakPolarHBondContact O-CB 3.32Å; T118-P121 VanDerWaalsContact O-CD 3.31Å; T118-P121 WeakPolarHBondContact O-CD 3.45Å; T118-Y122 PolarHBondContact O-N 3.21Å
119Q91Very high89.7Confident4 Ų421.8 Ų21.82%0.01912%0.122CC..Hα-helixtrans-62-41-174.7-175.4-179-95.200113.1S65 I115 Y122 F123S65-Q119 PolarHBondContact OG-NE2 3.37Å; I115-Q119 HydrophobicContact CG2-CB 4.1Å; I115-Q119 WeakPolarHBondContact O-CB 3.38Å; I115-Q119 PolarHBondContact O-N 3.07Å; Q119-Y122 WeakPolarHBondContact O-CB 3.21Å; Q119-Y122 PolarHBondContact O-N 3.28Å; Q119-F123 HydrophobicContact CG-CD2 3.97Å; Q119-F123 HydrophobicContact CG-CE2 3.68Å; Q119-F123 VanDerWaalsContact O-CD2 3.26Å; Q119-F123 WeakPolarHBondContact O-CD2 3.41Å; Q119-F123 PolarHBondContact O-N 3.24Å; Q119-F123 VanDerWaalsContact O-N 3.12Å
120G89.7Confident89.8Confident0 Ų019.5 Ų19.50%011%0.11CC..Hα-helixtrans-60.5-54.5175.100000112.8S65 S69 T118 Y122 F123 N124S65-G120 PolarHBondContact OG-N 3.1Å; S69-G120 WeakPolarHBondContact OG-CA 3.19Å; T118-G120 PolarHBondContact O-N 3.47Å; G120-Y122 VanDerWaalsContact C-N 3.26Å; G120-Y122 PolarHBondContact O-N 3.26Å; G120-F123 PolarHBondContact O-N 3.31Å; G120-F123 VanDerWaalsContact O-N 3.17Å; G120-N124 PolarHBondContact O-N 3.33Å; G120-N124 VanDerWaalsContact O-N 3.12Å
121P89Confident89.6Confident8 Ų816.8 Ų16.85%0.0529%0.091CC..Hα-helixtrans-50.5-38.5169.1-33.437.3000114.9S68 Y72 V76 T85 L117 T118 A125S68-P121 VanDerWaalsContact OG-CD 3.31Å; S68-P121 WeakPolarHBondContact OG-CD 3.36Å; Y72-P121 HydrophobicContact CD2-CB 3.88Å; V76-P121 HydrophobicContact CG1-CB 4.42Å; V76-P121 HydrophobicContact CG2-CB 4.22Å; V76-P121 HydrophobicContact CG2-CG 4.16Å; T85-P121 HydrophobicContact CG2-CB 3.69Å; T85-P121 WeakPolarHBondContact CG2-O 3.48Å; L117-P121 WeakPolarHBondContact O-CD 3.15Å; L117-P121 WeakPolarHBondContact O-CG 3.5Å; T118-P121 WeakPolarHBondContact O-CB 3.32Å; T118-P121 VanDerWaalsContact O-CD 3.31Å; T118-P121 WeakPolarHBondContact O-CD 3.45Å; P121-A125 WeakPolarHBondContact O-CB 3.37Å; P121-A125 PolarHBondContact O-N 3.33Å
122Y90.2Very high89.5Confident1 Ų116.7 Ų16.70%0.0049%0.089CC..Hα-helixtrans-60.4-51174.5158.4-87.1000112.3S30 Y33 L86 T89 Y90 T118 Q119 G120 N124 A125 L126S30-Y122 PolarHBondContact OG-OH 3.07Å; Y33-Y122 HydrophobicContact CD1-CE1 4.39Å; Y33-Y122 HydrophobicContact CD1-CE2 4.23Å; Y33-Y122 AromaticContact CD1-CZ 3.84Å; Y33-Y122 HydrophobicContact CE1-CD1 4.47Å; Y33-Y122 AromaticContact CE1-CE1 3.93Å; Y33-Y122 HydrophobicContact CE1-CE1 3.93Å; Y33-Y122 HydrophobicContact CE1-CE2 4.29Å; Y33-Y122 AromaticContact CE1-CZ 3.83Å; L86-Y122 HydrophobicContact CD2-CD2 3.51Å; L86-Y122 HydrophobicContact CD2-CE2 3.79Å; L86-Y122 HydrophobicContact CD2-CG 4.39Å; T89-Y122 HydrophobicContact CG2-CD2 4.44Å; T89-Y122 HydrophobicContact CG2-CG 4.15Å; T89-Y122 VanDerWaalsContact OG1-CB 3.28Å; T89-Y122 WeakPolarHBondContact OG1-CB 3.33Å; Y90-Y122 HydrophobicContact CE1-CD2 4.13Å; Y90-Y122 AromaticContact CE1-CE2 3.61Å; Y90-Y122 HydrophobicContact CE1-CE2 3.61Å; T118-Y122 PolarHBondContact O-N 3.21Å; Q119-Y122 WeakPolarHBondContact O-CB 3.21Å; Q119-Y122 PolarHBondContact O-N 3.28Å; G120-Y122 VanDerWaalsContact C-N 3.26Å; G120-Y122 PolarHBondContact O-N 3.26Å; Y122-N124 PolarHBondContact O-N 2.74Å; Y122-A125 PolarHBondContact O-N 3.09Å; Y122-L126 HydrophobicContact CE1-CD1 4.08Å; Y122-L126 HydrophobicContact CE2-CD1 3.97Å; Y122-L126 WeakPolarHBondContact O-CB 3.36Å; Y122-L126 PolarHBondContact O-N 3.14Å
123F88.5Confident89.4Confident41 Ų4116.8 Ų16.818%0.189%0.089CC..Hα-helixtrans-63.5-42.4-179-79.1-71.7000111.9Q119 G120 L126 Y127 H407Q119-F123 HydrophobicContact CG-CD2 3.97Å; Q119-F123 HydrophobicContact CG-CE2 3.68Å; Q119-F123 VanDerWaalsContact O-CD2 3.26Å; Q119-F123 WeakPolarHBondContact O-CD2 3.41Å; Q119-F123 PolarHBondContact O-N 3.24Å; Q119-F123 VanDerWaalsContact O-N 3.12Å; G120-F123 PolarHBondContact O-N 3.31Å; G120-F123 VanDerWaalsContact O-N 3.17Å; F123-L126 PolarHBondContact O-N 3.32Å; F123-Y127 HydrophobicContact CB-CE2 4.46Å; F123-Y127 HydrophobicContact CD1-CE2 4.45Å; F123-Y127 WeakPolarHBondContact O-CD2 3.36Å; F123-Y127 PolarHBondContact O-N 2.83Å; F123-H407 AromaticContact CD2-CE1 3.09Å; F123-H407 WeakPolarHBondContact CD2-CE1 3.22Å; F123-H407 AromaticContact CD2-ND1 3.98Å; F123-H407 AromaticContact CD2-NE2 3.31Å; F123-H407 VanDerWaalsContact CD2-NE2 3.31Å; F123-H407 WeakPolarHBondContact CD2-NE2 3.33Å; F123-H407 AromaticContact CE2-CE1 3.64Å; F123-H407 AromaticContact CG-CE1 3.39Å; F123-H407 WeakPolarHBondContact CG-CE1 3.3Å; F123-H407 AromaticContact CG-ND1 3.83Å; F123-H407 AromaticContact CG-NE2 3.7Å
124N87.3Confident89.2Confident8 Ų813.7 Ų13.74%0.0437%0.073CC..Hα-helixtrans-64.4-44.9176.3-71.4-9.5000112.3S69 Y72 G120 Y122 L126 A128S69-N124 PolarHBondContact O-ND2 2.68Å; Y72-N124 VanDerWaalsContact CB-ND2 3.32Å; Y72-N124 WeakPolarHBondContact CB-ND2 3.4Å; Y72-N124 HydrophobicContact CD1-CB 3.49Å; Y72-N124 VanDerWaalsContact CD1-CB 3.49Å; Y72-N124 HydrophobicContact CD2-CB 4.17Å; Y72-N124 HydrophobicContact CE1-CB 3.86Å; Y72-N124 HydrophobicContact CE2-CB 4.48Å; Y72-N124 HydrophobicContact CG-CB 3.67Å; G120-N124 PolarHBondContact O-N 3.33Å; G120-N124 VanDerWaalsContact O-N 3.12Å; Y122-N124 PolarHBondContact O-N 2.74Å; N124-L126 VanDerWaalsContact C-N 3.28Å; N124-L126 PolarHBondContact O-N 3.43Å; N124-A128 WeakPolarHBondContact O-CB 3.35Å; N124-A128 PolarHBondContact O-N 3.15Å
125A87.3Confident88.8Confident0 Ų011.7 Ų11.70%06%0.064CC..Hα-helixtrans-65.2-32.9176.700000112.5Y72 T85 P121 Y122 Y129Y72-A125 HydrophobicContact CE2-CB 4.03Å; T85-A125 HydrophobicContact CG2-CB 3.77Å; P121-A125 WeakPolarHBondContact O-CB 3.37Å; P121-A125 PolarHBondContact O-N 3.33Å; Y122-A125 PolarHBondContact O-N 3.09Å; A125-Y129 WeakPolarHBondContact O-CB 3.43Å; A125-Y129 PolarHBondContact O-N 3.28Å
126L89.8Confident88.5Confident0 Ų015.3 Ų15.30%08%0.077CC..Hα-helixtrans-69.5-51.8178.3-176.7143.3000111.7L26 L86 Y122 F123 N124 A128 Y129 L130 F156L26-L126 HydrophobicContact CD1-CD1 4.3Å; L26-L126 HydrophobicContact CD2-CG 4.36Å; L86-L126 HydrophobicContact CD2-CB 4.14Å; L86-L126 HydrophobicContact CD2-CD1 4.45Å; Y122-L126 HydrophobicContact CE1-CD1 4.08Å; Y122-L126 HydrophobicContact CE2-CD1 3.97Å; Y122-L126 WeakPolarHBondContact O-CB 3.36Å; Y122-L126 PolarHBondContact O-N 3.14Å; F123-L126 PolarHBondContact O-N 3.32Å; N124-L126 VanDerWaalsContact C-N 3.28Å; N124-L126 PolarHBondContact O-N 3.43Å; L126-A128 VanDerWaalsContact C-N 3.31Å; L126-A128 PolarHBondContact O-N 3.44Å; L126-Y129 PolarHBondContact O-N 3.38Å; L126-L130 WeakPolarHBondContact O-CB 3.39Å; L126-L130 PolarHBondContact O-N 3.46Å; L126-F156 HydrophobicContact CD1-CE2 3.69Å; L126-F156 HydrophobicContact CD1-CZ 3.55Å; L126-F156 HydrophobicContact CD2-CD1 4.31Å; L126-F156 HydrophobicContact CD2-CE1 3.73Å; L126-F156 HydrophobicContact CD2-CE2 4.03Å; L126-F156 HydrophobicContact CD2-CZ 3.59Å; L126-F156 HydrophobicContact CG-CE2 4.21Å; L126-F156 HydrophobicContact CG-CZ 4.1Å
127Y88.1Confident88.3Confident16 Ų1616.4 Ų16.46%0.0638%0.082CC..Hα-helixtrans-61.2-42.3173.5-70.4-59.8000110.7F123 Y129 L130 F131 L153 F403F123-Y127 HydrophobicContact CB-CE2 4.46Å; F123-Y127 HydrophobicContact CD1-CE2 4.45Å; F123-Y127 WeakPolarHBondContact O-CD2 3.36Å; F123-Y127 PolarHBondContact O-N 2.83Å; Y127-Y129 VanDerWaalsContact C-N 3.35Å; Y127-Y129 PolarHBondContact O-N 3.38Å; Y127-L130 PolarHBondContact O-N 3.18Å; Y127-L130 VanDerWaalsContact O-N 3.15Å; Y127-F131 HydrophobicContact CD1-CE2 4.06Å; Y127-F131 HydrophobicContact CG-CE2 4.44Å; Y127-F131 WeakPolarHBondContact O-CD2 3.37Å; Y127-F131 PolarHBondContact O-N 3.3Å; Y127-L153 HydrophobicContact CD1-CD2 4.34Å; Y127-L153 HydrophobicContact CE1-CD2 4.09Å; Y127-F403 HydrophobicContact CD1-CD1 4.12Å; Y127-F403 HydrophobicContact CD1-CE1 4.49Å; Y127-F403 HydrophobicContact CD2-CD1 4.43Å; Y127-F403 HydrophobicContact CE1-CD1 4.32Å; Y127-F403 HydrophobicContact CG-CD1 4.19Å
128A85.9Confident87.9Confident6 Ų612 Ų125%0.056%0.059CC..Hα-helixtrans-58.9-42.3175.700000112.8N124 L126 N132 W399N124-A128 WeakPolarHBondContact O-CB 3.35Å; N124-A128 PolarHBondContact O-N 3.15Å; L126-A128 VanDerWaalsContact C-N 3.31Å; L126-A128 PolarHBondContact O-N 3.44Å; A128-N132 VanDerWaalsContact O-CB 3.24Å; A128-N132 WeakPolarHBondContact O-CB 3.22Å; A128-N132 PolarHBondContact O-N 3Å; A128-N132 VanDerWaalsContact O-N 3.16Å; A128-N132 PolarHBondContact O-ND2 2.87Å; A128-W399 HydrophobicContact CB-CH2 4.43Å
129Y87.7Confident87.6Confident1 Ų119 Ų190%0.0049%0.085CC..Hα-helixtrans-64.6-41.8175-164.1-80000111.7N22 L26 H82 A125 L126 Y127 S133 L244 D245 L247N22-Y129 HydrophobicContact CB-CE1 4.05Å; N22-Y129 WeakPolarHBondContact CB-OH 2.98Å; L26-Y129 HydrophobicContact CD2-CD1 3.78Å; L26-Y129 HydrophobicContact CD2-CG 4.26Å; H82-Y129 HydrophobicContact CB-CD2 4.09Å; A125-Y129 WeakPolarHBondContact O-CB 3.43Å; A125-Y129 PolarHBondContact O-N 3.28Å; L126-Y129 PolarHBondContact O-N 3.38Å; Y127-Y129 VanDerWaalsContact C-N 3.35Å; Y127-Y129 PolarHBondContact O-N 3.38Å; Y129-S133 VanDerWaalsContact O-CB 3.23Å; Y129-S133 WeakPolarHBondContact O-CB 3.34Å; Y129-S133 PolarHBondContact O-N 2.87Å; Y129-S133 PolarHBondContact O-OG 3.32Å; Y129-L244 HydrophobicContact CE1-CD1 3.97Å; Y129-L244 HydrophobicContact CE2-CD1 4.44Å; Y129-L244 HydrophobicContact CE2-CD2 4.33Å; Y129-L244 HydrophobicContact CE2-CG 4.33Å; Y129-L244 WeakPolarHBondContact OH-CD1 3.23Å; Y129-D245 PolarHBondContact OH-O 2.8Å; Y129-L247 HydrophobicContact CD2-CB 3.97Å; Y129-L247 HydrophobicContact CD2-CD2 4.12Å; Y129-L247 HydrophobicContact CE2-CB 3.46Å; Y129-L247 VanDerWaalsContact CE2-CB 3.46Å; Y129-L247 HydrophobicContact CE2-CD2 4.23Å; Y129-L247 HydrophobicContact CE2-CG 4.44Å; Y129-L247 HydrophobicContact CG-CD2 4.3Å
130L90.4Very high87.2Confident2 Ų221.7 Ų21.71%0.0110%0.099CC..Hα-helixtrans-69.8-49-175.9-161.969.8000112.5V23 L126 Y127 S133 A134 F152 L153 F156V23-L130 HydrophobicContact CG1-CD1 3.84Å; V23-L130 HydrophobicContact CG2-CD1 4.26Å; L126-L130 WeakPolarHBondContact O-CB 3.39Å; L126-L130 PolarHBondContact O-N 3.46Å; Y127-L130 PolarHBondContact O-N 3.18Å; Y127-L130 VanDerWaalsContact O-N 3.15Å; L130-S133 WeakPolarHBondContact O-CB 3.32Å; L130-S133 PolarHBondContact O-N 3.47Å; L130-A134 WeakPolarHBondContact O-CB 3.32Å; L130-A134 PolarHBondContact O-N 3.41Å; L130-F152 HydrophobicContact CD1-CB 3.87Å; L130-F152 HydrophobicContact CG-CB 4.13Å; L130-L153 HydrophobicContact CD2-CD2 3.57Å; L130-L153 HydrophobicContact CD2-CG 3.88Å; L130-F156 HydrophobicContact CD1-CB 4.29Å; L130-F156 HydrophobicContact CD2-CB 4.18Å; L130-F156 HydrophobicContact CD2-CG 4.42Å
131F87.7Confident86.9Confident7 Ų722.9 Ų22.93%0.03111%0.108CC..Hα-helixtrans-68.7-38.9178-73.5-68.6000112.4Y127 S133 A134 A135 A149 L153 Y392 W399 F403Y127-F131 HydrophobicContact CD1-CE2 4.06Å; Y127-F131 HydrophobicContact CG-CE2 4.44Å; Y127-F131 WeakPolarHBondContact O-CD2 3.37Å; Y127-F131 PolarHBondContact O-N 3.3Å; F131-S133 VanDerWaalsContact C-N 3.3Å; F131-S133 PolarHBondContact O-N 2.87Å; F131-A134 PolarHBondContact O-N 2.89Å; F131-A135 WeakPolarHBondContact O-CB 3.42Å; F131-A135 PolarHBondContact O-N 3.04Å; F131-A149 HydrophobicContact CD1-CB 3.72Å; F131-A149 HydrophobicContact CE1-CB 3.69Å; F131-L153 HydrophobicContact CE1-CD1 4.27Å; F131-L153 HydrophobicContact CZ-CD1 4.03Å; F131-Y392 HydrophobicContact CD1-CD2 4.1Å; F131-Y392 AromaticContact CD1-CE2 3.83Å; F131-Y392 HydrophobicContact CD1-CE2 3.83Å; F131-Y392 AromaticContact CE1-CD2 3.52Å; F131-Y392 HydrophobicContact CE1-CD2 3.52Å; F131-Y392 AromaticContact CE1-CE2 3.69Å; F131-Y392 HydrophobicContact CE1-CE2 3.69Å; F131-Y392 HydrophobicContact CZ-CD2 4.18Å; F131-W399 HydrophobicContact CB-CD2 4.08Å; F131-W399 HydrophobicContact CB-CE3 3.76Å; F131-W399 HydrophobicContact CB-CH2 3.67Å; F131-W399 HydrophobicContact CB-CZ2 3.95Å; F131-W399 HydrophobicContact CB-CZ3 3.57Å; F131-W399 HydrophobicContact CD2-CD2 4.49Å; F131-W399 AromaticContact CD2-CE3 3.65Å; F131-W399 HydrophobicContact CD2-CE3 3.65Å; F131-W399 AromaticContact CD2-CZ3 3.79Å; F131-W399 HydrophobicContact CD2-CZ3 3.79Å; F131-W399 HydrophobicContact CG-CD2 4.3Å; F131-W399 AromaticContact CG-CE3 3.85Å; F131-W399 HydrophobicContact CG-CE3 3.85Å; F131-W399 HydrophobicContact CG-CZ3 4.03Å; F131-F403 HydrophobicContact CE1-CE2 4.41Å; F131-F403 HydrophobicContact CE1-CZ 4.38Å; F131-F403 AromaticContact CE2-CD1 3.87Å; F131-F403 HydrophobicContact CE2-CD1 3.87Å; F131-F403 AromaticContact CE2-CD2 3.92Å; F131-F403 HydrophobicContact CE2-CD2 3.92Å; F131-F403 AromaticContact CE2-CE1 3.81Å; F131-F403 HydrophobicContact CE2-CE1 3.81Å; F131-F403 AromaticContact CE2-CE2 3.87Å; F131-F403 HydrophobicContact CE2-CE2 3.87Å; F131-F403 AromaticContact CE2-CG 3.94Å; F131-F403 HydrophobicContact CE2-CG 3.94Å; F131-F403 AromaticContact CE2-CZ 3.82Å; F131-F403 HydrophobicContact CE2-CZ 3.82Å; F131-F403 HydrophobicContact CZ-CD1 4.25Å; F131-F403 HydrophobicContact CZ-CD2 4.13Å; F131-F403 AromaticContact CZ-CE1 3.71Å; F131-F403 HydrophobicContact CZ-CE1 3.71Å; F131-F403 AromaticContact CZ-CE2 3.58Å; F131-F403 HydrophobicContact CZ-CE2 3.58Å; F131-F403 HydrophobicContact CZ-CG 4.45Å; F131-F403 AromaticContact CZ-CZ 3.36Å; F131-F403 HydrophobicContact CZ-CZ 3.36Å
132N85.3Confident86.4Confident15 Ų1531.9 Ų31.98%0.0815%0.146CC..Hα-helixtrans-66-32.8172.9-78.5-62.8000112.6A128 R136 L247 V249A128-N132 VanDerWaalsContact O-CB 3.24Å; A128-N132 WeakPolarHBondContact O-CB 3.22Å; A128-N132 PolarHBondContact O-N 3Å; A128-N132 VanDerWaalsContact O-N 3.16Å; A128-N132 PolarHBondContact O-ND2 2.87Å; N132-R136 WeakPolarHBondContact O-CG 3.4Å; N132-R136 PolarHBondContact O-N 3.14Å; N132-L247 HydrophobicContact CB-CD2 3.97Å; N132-V249 HydrophobicContact CB-CG2 4.08Å; N132-V249 WeakPolarHBondContact OD1-CG1 3.28Å
133S88Confident85.8Confident2 Ų234.6 Ų34.61%0.01416%0.159CC..Hα-helixtrans-67.6-43.5171.3-64.90000111.3Y129 L130 F131 R136 F137Y129-S133 VanDerWaalsContact O-CB 3.23Å; Y129-S133 WeakPolarHBondContact O-CB 3.34Å; Y129-S133 PolarHBondContact O-N 2.87Å; Y129-S133 PolarHBondContact O-OG 3.32Å; L130-S133 WeakPolarHBondContact O-CB 3.32Å; L130-S133 PolarHBondContact O-N 3.47Å; F131-S133 VanDerWaalsContact C-N 3.3Å; F131-S133 PolarHBondContact O-N 2.87Å; S133-R136 PolarHBondContact O-N 2.91Å; S133-F137 PolarHBondContact O-N 3.43Å
134A88.6Confident85.5Confident0 Ų037.1 Ų37.10%018%0.178CC..Hα-helixtrans-61.9-46.4177.300000112.2L130 F131 R136 F137 S138 A149 F152L130-A134 WeakPolarHBondContact O-CB 3.32Å; L130-A134 PolarHBondContact O-N 3.41Å; F131-A134 PolarHBondContact O-N 2.89Å; A134-R136 PolarHBondContact O-N 2.9Å; A134-F137 WeakPolarHBondContact O-CA 3.21Å; A134-F137 WeakPolarHBondContact O-CB 3.32Å; A134-F137 PolarHBondContact O-N 2.94Å; A134-S138 PolarHBondContact O-N 3.39Å; A134-S138 PolarHBondContact O-OG 3.16Å; A134-A149 HydrophobicContact CB-CB 3.88Å; A134-F152 HydrophobicContact CB-CD2 3.8Å; A134-F152 HydrophobicContact CB-CE2 4.33Å
135A84.9Confident85.3Confident23 Ų2339.2 Ų39.219%0.1919%0.191CC..Hα-helixtrans-55.8-49175.600000111.8F131 F137 S138 Y139 V145F131-A135 WeakPolarHBondContact O-CB 3.42Å; F131-A135 PolarHBondContact O-N 3.04Å; A135-F137 VanDerWaalsContact C-N 3.28Å; A135-F137 PolarHBondContact O-N 2.87Å; A135-S138 VanDerWaalsContact CA-OG 3.3Å; A135-S138 WeakPolarHBondContact CA-OG 3.26Å; A135-S138 PolarHBondContact O-N 2.85Å; A135-S138 PolarHBondContact O-OG 3.45Å; A135-Y139 WeakPolarHBondContact O-CD2 3.49Å; A135-Y139 PolarHBondContact O-N 2.95Å; A135-Y139 VanDerWaalsContact O-N 3.11Å; A135-V145 HydrophobicContact CB-CG1 4.21Å
136R84.9Confident85Confident77 Ų7740.8 Ų40.829%0.29120%0.201SC..Hα-helixtrans-60.4-36.1174.8-71.5176.4-176.6-152.2-2.9112.7I19 N132 S133 A134 L140 Q248I19-R136 HydrophobicContact CD1-CB 3.87Å; N132-R136 WeakPolarHBondContact O-CG 3.4Å; N132-R136 PolarHBondContact O-N 3.14Å; S133-R136 PolarHBondContact O-N 2.91Å; A134-R136 PolarHBondContact O-N 2.9Å; R136-L140 WeakPolarHBondContact O-CD1 3.12Å; R136-L140 WeakPolarHBondContact O-CG 3.28Å; R136-L140 PolarHBondContact O-N 3.46Å; R136-Q248 PolarHBondContact NH2-O 2.89Å
137F87.9Confident84.7Confident22 Ų2243.1 Ų43.110%0.09621%0.212CC..Hα-helixtrans-70.2-43176.7-169.9-95.5000112.4K16 I19 I20 S133 A134 A135 Y139 L140 S141 F152K16-F137 HydrophobicContact CB-CE2 4.14Å; K16-F137 HydrophobicContact CD-CE2 4.22Å; K16-F137 HydrophobicContact CG-CD2 4.48Å; K16-F137 HydrophobicContact CG-CE2 4.17Å; I19-F137 HydrophobicContact CG2-CB 4.34Å; I20-F137 HydrophobicContact CD1-CE2 3.85Å; I20-F137 HydrophobicContact CD1-CZ 4.39Å; I20-F137 HydrophobicContact CG1-CE2 4.12Å; S133-F137 PolarHBondContact O-N 3.43Å; A134-F137 WeakPolarHBondContact O-CA 3.21Å; A134-F137 WeakPolarHBondContact O-CB 3.32Å; A134-F137 PolarHBondContact O-N 2.94Å; A135-F137 VanDerWaalsContact C-N 3.28Å; A135-F137 PolarHBondContact O-N 2.87Å; F137-Y139 PolarHBondContact O-N 3.49Å; F137-L140 PolarHBondContact O-N 3.2Å; F137-L140 VanDerWaalsContact O-N 3.13Å; F137-S141 VanDerWaalsContact CE1-OG 3.32Å; F137-S141 WeakPolarHBondContact CE1-OG 3.39Å; F137-S141 WeakPolarHBondContact CZ-OG 3.48Å; F137-S141 WeakPolarHBondContact O-CB 3.47Å; F137-S141 PolarHBondContact O-N 3.16Å; F137-S141 PolarHBondContact O-OG 3.29Å; F137-F152 HydrophobicContact CB-CE2 3.83Å; F137-F152 HydrophobicContact CB-CZ 3.63Å; F137-F152 HydrophobicContact CD1-CE1 4.49Å; F137-F152 HydrophobicContact CD1-CZ 4.13Å; F137-F152 AromaticContact CD2-CZ 3.88Å; F137-F152 HydrophobicContact CD2-CZ 3.88Å; F137-F152 HydrophobicContact CG-CE1 4.35Å; F137-F152 HydrophobicContact CG-CE2 4.31Å; F137-F152 AromaticContact CG-CZ 3.6Å; F137-F152 HydrophobicContact CG-CZ 3.6Å
138S84.6Confident84.7Confident4 Ų442.3 Ų42.33%0.02821%0.209CC..Hα-helixtrans-58.8-45.7175.333.10000112.3A134 A135 L140 S141 F142 E143A134-S138 PolarHBondContact O-N 3.39Å; A134-S138 PolarHBondContact O-OG 3.16Å; A135-S138 VanDerWaalsContact CA-OG 3.3Å; A135-S138 WeakPolarHBondContact CA-OG 3.26Å; A135-S138 PolarHBondContact O-N 2.85Å; A135-S138 PolarHBondContact O-OG 3.45Å; S138-L140 PolarHBondContact O-N 3.06Å; S138-S141 PolarHBondContact O-N 3.47Å; S138-S141 VanDerWaalsContact O-N 3.11Å; S138-F142 PolarHBondContact O-N 3.35Å; S138-E143 WeakPolarHBondContact CB-O 3.36Å
139Y82.2Confident84.8Confident163 Ų16342.1 Ų42.164%0.63921%0.208SC*.Hα-helixtrans-60.7-30.1175.9-69.5-59.9000113.5A135 F137A135-Y139 WeakPolarHBondContact O-CD2 3.49Å; A135-Y139 PolarHBondContact O-N 2.95Å; A135-Y139 VanDerWaalsContact O-N 3.11Å; F137-Y139 PolarHBondContact O-N 3.49Å
140L83.9Confident84.7Confident59 Ų5942.5 Ų42.531%0.30921%0.209SC..Hα-helixtrans-86-19.7177.2-69.7168.2000113.4P15 K16 I19 R136 F137 S138P15-L140 HydrophobicContact CB-CD1 4Å; P15-L140 HydrophobicContact CG-CD1 4.22Å; P15-L140 HydrophobicContact CG-CD2 4.42Å; K16-L140 VanDerWaalsContact CE-C 3.47Å; K16-L140 WeakPolarHBondContact CE-O 3.45Å; K16-L140 HydrophobicContact CG-CB 4.06Å; K16-L140 HydrophobicContact CG-CD1 4.27Å; K16-L140 PolarHBondContact NZ-O 3.32Å; I19-L140 HydrophobicContact CD1-CD1 3.7Å; R136-L140 WeakPolarHBondContact O-CD1 3.12Å; R136-L140 WeakPolarHBondContact O-CG 3.28Å; R136-L140 PolarHBondContact O-N 3.46Å; F137-L140 PolarHBondContact O-N 3.2Å; F137-L140 VanDerWaalsContact O-N 3.13Å; S138-L140 PolarHBondContact O-N 3.06Å
141S82.5Confident84.7Confident25 Ų2547.4 Ų47.418%0.17523%0.228CC..Hα-helixtrans-113.1-3.7-173.2-64.20000114.6K16 F137 S138 E143K16-S141 WeakPolarHBondContact CE-OG 3.39Å; K16-S141 PolarHBondContact NZ-OG 3.09Å; F137-S141 VanDerWaalsContact CE1-OG 3.32Å; F137-S141 WeakPolarHBondContact CE1-OG 3.39Å; F137-S141 WeakPolarHBondContact CZ-OG 3.48Å; F137-S141 WeakPolarHBondContact O-CB 3.47Å; F137-S141 PolarHBondContact O-N 3.16Å; F137-S141 PolarHBondContact O-OG 3.29Å; S138-S141 PolarHBondContact O-N 3.47Å; S138-S141 VanDerWaalsContact O-N 3.11Å; S141-E143 PolarHBondContact O-N 3.48Å
142F77.8Confident84.9Confident197 Ų19747.4 Ų47.486%0.86423%0.228SC*.THydrogen-bonded Turntrans56.324.5-175.4-53.6-78.1000113.7S138S138-F142 PolarHBondContact O-N 3.35Å
143E78.6Confident85.2Confident59 Ų5947 Ų4728%0.27623%0.225SC..  trans-93.7162.6171.9-66.1-169.8179.700110.9S138 S141 H147 R151S138-E143 WeakPolarHBondContact CB-O 3.36Å; S141-E143 PolarHBondContact O-N 3.48Å; E143-H147 IonicContact OE1-ND1 3.06Å; E143-H147 IonicContact OE2-CE1 2.73Å; E143-H147 PolarHBondContact OE2-CE1 2.76Å; E143-H147 IonicContact OE2-CG 2.79Å; E143-H147 IonicContact OE2-ND1 3.24Å; E143-H147 PolarHBondContact OE2-ND1 3.44Å; E143-R151 IonicContact OE1-CZ 2.75Å; E143-R151 IonicContact OE1-NH1 2.88Å; E143-R151 PolarHBondContact OE1-NH1 3.38Å; E143-R151 IonicContact OE1-NH2 2.71Å; E143-R151 IonicContact OE2-CZ 2.87Å; E143-R151 IonicContact OE2-NH1 3.2Å; E143-R151 PolarHBondContact OE2-NH1 2.91Å
144T81.4Confident85.4Confident94 Ų9447.7 Ų47.758%0.57723%0.23SC*.  trans-67.7143.9171.867.70000111.3C146 H147 S148T144-C146 PolarHBondContact O-N 3.03Å; T144-H147 PolarHBondContact O-N 2.98Å; T144-H147 VanDerWaalsContact O-N 3.15Å; T144-H147 WeakPolarHBondContact OG1-CB 3.45Å; T144-H147 PolarHBondContact OG1-N 2.83Å; T144-S148 PolarHBondContact O-N 3.16Å; T144-S148 VanDerWaalsContact O-N 3.1Å
145V83Confident85.6Confident51 Ų5150.3 Ų50.331%0.30924%0.244SC..Hα-helixtrans-55.3-40.4176.7-170.60000110.8A135 H147 S148 A149 Y392A135-V145 HydrophobicContact CB-CG1 4.21Å; V145-H147 PolarHBondContact O-N 3.48Å; V145-S148 PolarHBondContact O-N 2.77Å; V145-A149 VanDerWaalsContact O-CB 3.28Å; V145-A149 WeakPolarHBondContact O-CB 3.35Å; V145-A149 PolarHBondContact O-N 2.77Å; V145-Y392 WeakPolarHBondContact CG1-OH 3.28Å
146C81.8Confident86Confident33 Ų3349.6 Ų49.622%0.22324%0.236CC..Hα-helixtrans-57.4-48177.5-173.40000112.5T144 A149 H150 Y392T144-C146 PolarHBondContact O-N 3.03Å; C146-A149 PolarHBondContact O-N 3.46Å; C146-H150 PolarHBondContact O-N 3.38Å; C146-H150 PolarHBondContact O-ND1 3.18Å; C146-H150 VanDerWaalsContact SG-CE1 3.52Å; C146-Y392 HydrophobicContact CB-CD1 4.46Å; C146-Y392 HydrophobicContact CB-CE1 3.75Å
147H84Confident86.4Confident49 Ų4946.7 Ų46.723%0.22723%0.226CC..Hα-helixtrans-66.7-43.2179.6-175.9-115.2000111.8E143 T144 V145 A149 H150 R151 F334E143-H147 IonicContact OE1-ND1 3.06Å; E143-H147 IonicContact OE2-CE1 2.73Å; E143-H147 PolarHBondContact OE2-CE1 2.76Å; E143-H147 IonicContact OE2-CG 2.79Å; E143-H147 IonicContact OE2-ND1 3.24Å; E143-H147 PolarHBondContact OE2-ND1 3.44Å; T144-H147 PolarHBondContact O-N 2.98Å; T144-H147 VanDerWaalsContact O-N 3.15Å; T144-H147 WeakPolarHBondContact OG1-CB 3.45Å; T144-H147 PolarHBondContact OG1-N 2.83Å; V145-H147 PolarHBondContact O-N 3.48Å; H147-A149 VanDerWaalsContact C-N 3.32Å; H147-A149 PolarHBondContact O-N 3.2Å; H147-H150 PolarHBondContact O-N 3.45Å; H147-R151 PolarHBondContact CE1-NE 3.18Å; H147-R151 VanDerWaalsContact CE1-NE 3.28Å; H147-R151 PolarHBondContact CE1-NH2 2.96Å; H147-R151 VanDerWaalsContact CE1-NH2 3.33Å; H147-R151 WeakPolarHBondContact O-CG 3.21Å; H147-R151 PolarHBondContact O-N 3.4Å; H147-R151 VanDerWaalsContact O-N 3.08Å; H147-F334 AromaticContact CD2-CE1 3.64Å; H147-F334 AromaticContact CD2-CE2 3.88Å; H147-F334 AromaticContact CD2-CZ 3.5Å
148S87Confident86.7Confident0 Ų047.8 Ų47.80%023%0.233CC..Hα-helixtrans-61-40.1174.5-66.90000112.1T144 V145 R151 F152T144-S148 PolarHBondContact O-N 3.16Å; T144-S148 VanDerWaalsContact O-N 3.1Å; V145-S148 PolarHBondContact O-N 2.77Å; S148-R151 PolarHBondContact O-N 3.08Å; S148-F152 WeakPolarHBondContact O-CG 3.41Å; S148-F152 PolarHBondContact O-N 3.32Å; S148-F152 VanDerWaalsContact O-N 3.09Å
149A88Confident87.2Confident2 Ų249.6 Ų49.62%0.01724%0.241CC..Hα-helixtrans-68.2-46.3179.500000112.7F131 A134 V145 C146 H147 R151 F152 L153 Y392F131-A149 HydrophobicContact CD1-CB 3.72Å; F131-A149 HydrophobicContact CE1-CB 3.69Å; A134-A149 HydrophobicContact CB-CB 3.88Å; V145-A149 VanDerWaalsContact O-CB 3.28Å; V145-A149 WeakPolarHBondContact O-CB 3.35Å; V145-A149 PolarHBondContact O-N 2.77Å; C146-A149 PolarHBondContact O-N 3.46Å; H147-A149 VanDerWaalsContact C-N 3.32Å; H147-A149 PolarHBondContact O-N 3.2Å; A149-R151 VanDerWaalsContact C-N 3.31Å; A149-R151 PolarHBondContact O-N 3.39Å; A149-F152 PolarHBondContact O-N 2.85Å; A149-F152 VanDerWaalsContact O-N 3.15Å; A149-L153 WeakPolarHBondContact O-CB 3.26Å; A149-L153 WeakPolarHBondContact O-CG 3.31Å; A149-L153 PolarHBondContact O-N 2.97Å; A149-Y392 HydrophobicContact CB-CE2 4.48Å
150H86.7Confident87.8Confident8 Ų842.2 Ų42.24%0.03721%0.213CC..Hα-helixtrans-62.9-35.7176.1-75.982.5000112.4C146 H147 C154 H330 F334 R389C146-H150 PolarHBondContact O-N 3.38Å; C146-H150 PolarHBondContact O-ND1 3.18Å; C146-H150 VanDerWaalsContact SG-CE1 3.52Å; H147-H150 PolarHBondContact O-N 3.45Å; H150-C154 WeakPolarHBondContact O-CB 3.11Å; H150-C154 PolarHBondContact O-N 2.97Å; H150-H330 PolarHBondContact O-CD2 3.35Å; H150-F334 HydrophobicContact CB-CZ 3.81Å; H150-R389 WeakPolarHBondContact NE2-CB 3.47Å; H150-R389 WeakPolarHBondContact NE2-CD 3.47Å; H150-R389 WeakPolarHBondContact NE2-CG 2.95Å
151R89.4Confident88.3Confident106 Ų10639.5 Ų39.540%0.420%0.199SC..Hα-helixtrans-63.1-42.2172.1-77.3170.9161.3-169.4-5.8112.3E143 H147 S148 A149 C154 I155E143-R151 IonicContact OE1-CZ 2.75Å; E143-R151 IonicContact OE1-NH1 2.88Å; E143-R151 PolarHBondContact OE1-NH1 3.38Å; E143-R151 IonicContact OE1-NH2 2.71Å; E143-R151 IonicContact OE2-CZ 2.87Å; E143-R151 IonicContact OE2-NH1 3.2Å; E143-R151 PolarHBondContact OE2-NH1 2.91Å; H147-R151 PolarHBondContact CE1-NE 3.18Å; H147-R151 VanDerWaalsContact CE1-NE 3.28Å; H147-R151 PolarHBondContact CE1-NH2 2.96Å; H147-R151 VanDerWaalsContact CE1-NH2 3.33Å; H147-R151 WeakPolarHBondContact O-CG 3.21Å; H147-R151 PolarHBondContact O-N 3.4Å; H147-R151 VanDerWaalsContact O-N 3.08Å; S148-R151 PolarHBondContact O-N 3.08Å; A149-R151 VanDerWaalsContact C-N 3.31Å; A149-R151 PolarHBondContact O-N 3.39Å; R151-C154 WeakPolarHBondContact O-CB 3.38Å; R151-C154 PolarHBondContact O-N 3.35Å; R151-I155 WeakPolarHBondContact O-CG1 3.21Å; R151-I155 PolarHBondContact O-N 3.26Å; R151-I155 VanDerWaalsContact O-N 3.14Å
152F92.1Very high88.9Confident7 Ų740 Ų403%0.03120%0.202CC..Hα-helixtrans-74.1-35.7179.1-721.6000112.6I19 V23 L130 A134 F137 S148 A149 I155 F156I19-F152 HydrophobicContact CG2-CE2 3.72Å; I19-F152 HydrophobicContact CG2-CZ 3.9Å; V23-F152 HydrophobicContact CG1-CB 4.18Å; V23-F152 HydrophobicContact CG1-CD1 4.48Å; V23-F152 HydrophobicContact CG1-CG 4.22Å; V23-F152 HydrophobicContact CG2-CD2 3.72Å; V23-F152 HydrophobicContact CG2-CE2 3.9Å; V23-F152 HydrophobicContact CG2-CG 4.09Å; V23-F152 HydrophobicContact CG2-CZ 4.42Å; L130-F152 HydrophobicContact CD1-CB 3.87Å; L130-F152 HydrophobicContact CG-CB 4.13Å; A134-F152 HydrophobicContact CB-CD2 3.8Å; A134-F152 HydrophobicContact CB-CE2 4.33Å; F137-F152 HydrophobicContact CB-CE2 3.83Å; F137-F152 HydrophobicContact CB-CZ 3.63Å; F137-F152 HydrophobicContact CD1-CE1 4.49Å; F137-F152 HydrophobicContact CD1-CZ 4.13Å; F137-F152 AromaticContact CD2-CZ 3.88Å; F137-F152 HydrophobicContact CD2-CZ 3.88Å; F137-F152 HydrophobicContact CG-CE1 4.35Å; F137-F152 HydrophobicContact CG-CE2 4.31Å; F137-F152 AromaticContact CG-CZ 3.6Å; F137-F152 HydrophobicContact CG-CZ 3.6Å; S148-F152 WeakPolarHBondContact O-CG 3.41Å; S148-F152 PolarHBondContact O-N 3.32Å; S148-F152 VanDerWaalsContact O-N 3.09Å; A149-F152 PolarHBondContact O-N 2.85Å; A149-F152 VanDerWaalsContact O-N 3.15Å; F152-I155 HydrophobicContact CD1-CD1 4.35Å; F152-I155 PolarHBondContact O-N 3.42Å; F152-F156 VanDerWaalsContact O-CB 3.26Å; F152-F156 WeakPolarHBondContact O-CB 3.34Å; F152-F156 PolarHBondContact O-N 3.45Å
153L91Very high89.7Confident5 Ų530.7 Ų30.73%0.02616%0.162CC..Hα-helixtrans-59.7-43.2167.9-75.6162.6000111.6Y127 L130 F131 A149 F156 H157Y127-L153 HydrophobicContact CD1-CD2 4.34Å; Y127-L153 HydrophobicContact CE1-CD2 4.09Å; L130-L153 HydrophobicContact CD2-CD2 3.57Å; L130-L153 HydrophobicContact CD2-CG 3.88Å; F131-L153 HydrophobicContact CE1-CD1 4.27Å; F131-L153 HydrophobicContact CZ-CD1 4.03Å; A149-L153 WeakPolarHBondContact O-CB 3.26Å; A149-L153 WeakPolarHBondContact O-CG 3.31Å; A149-L153 PolarHBondContact O-N 2.97Å; L153-F156 PolarHBondContact O-N 2.88Å; L153-H157 VanDerWaalsContact O-CB 3.3Å; L153-H157 WeakPolarHBondContact O-CB 3.22Å; L153-H157 PolarHBondContact O-N 3.43Å; L153-H157 PolarHBondContact O-ND1 3.48Å
154C92.8Very high90.5Very high17 Ų1728.3 Ų28.312%0.11515%0.15CC..Hα-helixtrans-57.7-54.3175.6-174.30000111.8H150 R151 F156 H157 L158 H330H150-C154 WeakPolarHBondContact O-CB 3.11Å; H150-C154 PolarHBondContact O-N 2.97Å; R151-C154 WeakPolarHBondContact O-CB 3.38Å; R151-C154 PolarHBondContact O-N 3.35Å; C154-F156 VanDerWaalsContact C-N 3.31Å; C154-F156 PolarHBondContact O-N 2.85Å; C154-H157 PolarHBondContact O-N 3.15Å; C154-L158 WeakPolarHBondContact O-CB 3.04Å; C154-L158 WeakPolarHBondContact O-CG 3.43Å; C154-L158 PolarHBondContact O-N 3.36Å; C154-H330 HydrophobicContact CB-CB 3.62Å
155I93.1Very high91.2Very high56 Ų5624 Ų2429%0.28712%0.124SC..Hα-helixtrans-57.3-45.5178.3-66.3165.3000110.9V23 V24 R151 F152 L159V23-I155 HydrophobicContact CG1-CB 4.49Å; V23-I155 HydrophobicContact CG1-CG2 4.21Å; V24-I155 HydrophobicContact CG2-CG2 4.15Å; R151-I155 WeakPolarHBondContact O-CG1 3.21Å; R151-I155 PolarHBondContact O-N 3.26Å; R151-I155 VanDerWaalsContact O-N 3.14Å; F152-I155 HydrophobicContact CD1-CD1 4.35Å; F152-I155 PolarHBondContact O-N 3.42Å; I155-L159 HydrophobicContact CG2-CD1 4.13Å; I155-L159 WeakPolarHBondContact O-CG 3.47Å; I155-L159 PolarHBondContact O-N 3.33Å; I155-L159 VanDerWaalsContact O-N 3.16Å
156F93.9Very high91.7Very high8 Ų828 Ų284%0.03513%0.134CC..Hα-helixtrans-63.3-48.4180174.3-100.1000112.8S30 L126 L130 F152 L153 C154 L159 T160S30-F156 WeakPolarHBondContact OG-CE2 3.05Å; L126-F156 HydrophobicContact CD1-CE2 3.69Å; L126-F156 HydrophobicContact CD1-CZ 3.55Å; L126-F156 HydrophobicContact CD2-CD1 4.31Å; L126-F156 HydrophobicContact CD2-CE1 3.73Å; L126-F156 HydrophobicContact CD2-CE2 4.03Å; L126-F156 HydrophobicContact CD2-CZ 3.59Å; L126-F156 HydrophobicContact CG-CE2 4.21Å; L126-F156 HydrophobicContact CG-CZ 4.1Å; L130-F156 HydrophobicContact CD1-CB 4.29Å; L130-F156 HydrophobicContact CD2-CB 4.18Å; L130-F156 HydrophobicContact CD2-CG 4.42Å; F152-F156 VanDerWaalsContact O-CB 3.26Å; F152-F156 WeakPolarHBondContact O-CB 3.34Å; F152-F156 PolarHBondContact O-N 3.45Å; L153-F156 PolarHBondContact O-N 2.88Å; C154-F156 VanDerWaalsContact C-N 3.31Å; C154-F156 PolarHBondContact O-N 2.85Å; F156-L159 PolarHBondContact O-N 3.15Å; F156-T160 VanDerWaalsContact CZ-OG1 3.25Å; F156-T160 WeakPolarHBondContact CZ-OG1 3.39Å; F156-T160 WeakPolarHBondContact O-CB 3.49Å; F156-T160 PolarHBondContact O-N 3.12Å; F156-T160 PolarHBondContact O-OG1 3.38Å
157H92.5Very high92.2Very high15 Ų1526.4 Ų26.47%0.06912%0.124CC..Hα-helixtrans-69.5-33.2-179.8-72.5140.8000112.5L153 C154 T160 H161 S326 H330 E388L153-H157 VanDerWaalsContact O-CB 3.3Å; L153-H157 WeakPolarHBondContact O-CB 3.22Å; L153-H157 PolarHBondContact O-N 3.43Å; L153-H157 PolarHBondContact O-ND1 3.48Å; C154-H157 PolarHBondContact O-N 3.15Å; H157-T160 PolarHBondContact O-N 3.11Å; H157-H161 WeakPolarHBondContact O-CB 3.46Å; H157-H161 PolarHBondContact O-CD2 3.36Å; H157-H161 PolarHBondContact O-N 3.4Å; H157-S326 WeakPolarHBondContact CB-OG 3.37Å; H157-H330 AromaticContact ND1-CE1 3.96Å; H157-H330 AromaticContact ND1-NE2 3.98Å; H157-E388 IonicContact CE1-OE1 2.83Å; H157-E388 IonicContact CE1-OE2 3.48Å; H157-E388 PolarHBondContact CE1-OE2 3.46Å; H157-E388 IonicContact NE2-OE1 3.63Å
158L94.9Very high92.6Very high46 Ų4624.2 Ų24.224%0.24111%0.113CC..Hα-helixtrans-61.3-52172.6-75.4170.1000111.7C154 T160 H161 C162 L323 A327C154-L158 WeakPolarHBondContact O-CB 3.04Å; C154-L158 WeakPolarHBondContact O-CG 3.43Å; C154-L158 PolarHBondContact O-N 3.36Å; L158-T160 VanDerWaalsContact C-N 3.31Å; L158-T160 PolarHBondContact O-N 3.02Å; L158-H161 PolarHBondContact O-N 2.78Å; L158-C162 WeakPolarHBondContact O-CB 3.33Å; L158-C162 PolarHBondContact O-N 3.1Å; L158-L323 HydrophobicContact CB-CD1 4.25Å; L158-L323 HydrophobicContact CD2-CD1 3.71Å; L158-L323 HydrophobicContact CD2-CG 4.32Å; L158-L323 WeakPolarHBondContact CD2-O 3.45Å; L158-L323 WeakPolarHBondContact O-CD1 3.38Å; L158-A327 HydrophobicContact CD1-CB 4.15Å; L158-A327 HydrophobicContact CD2-CB 3.85Å
159L95.3Very high92.9Very high41 Ų4126.7 Ų26.722%0.21513%0.126CC..Hα-helixtrans-61.7-41.8177.4-67.9167.7000111.2V24 M31 I155 F156 C162 G163V24-L159 HydrophobicContact CG1-CD1 4.35Å; M31-L159 WeakPolarHBondContact CB-O 3.28Å; M31-L159 VanDerWaalsContact CG-O 3.22Å; M31-L159 WeakPolarHBondContact CG-O 3.17Å; I155-L159 HydrophobicContact CG2-CD1 4.13Å; I155-L159 WeakPolarHBondContact O-CG 3.47Å; I155-L159 PolarHBondContact O-N 3.33Å; I155-L159 VanDerWaalsContact O-N 3.16Å; F156-L159 PolarHBondContact O-N 3.15Å; L159-C162 WeakPolarHBondContact O-CB 3.42Å; L159-C162 PolarHBondContact O-N 3.25Å; L159-G163 PolarHBondContact O-N 2.94Å; L159-G163 VanDerWaalsContact O-N 3.09Å
160T93.7Very high93Very high8 Ų829.5 Ų29.55%0.04914%0.14CC..Hα-helixtrans-62.8-44.5178.3-60.60000112.7C34 F156 H157 L158 G163 W164C34-T160 HydrophobicContact CB-CG2 3.93Å; F156-T160 VanDerWaalsContact CZ-OG1 3.25Å; F156-T160 WeakPolarHBondContact CZ-OG1 3.39Å; F156-T160 WeakPolarHBondContact O-CB 3.49Å; F156-T160 PolarHBondContact O-N 3.12Å; F156-T160 PolarHBondContact O-OG1 3.38Å; H157-T160 PolarHBondContact O-N 3.11Å; L158-T160 VanDerWaalsContact C-N 3.31Å; L158-T160 PolarHBondContact O-N 3.02Å; T160-G163 WeakPolarHBondContact O-CA 3.39Å; T160-G163 PolarHBondContact O-N 3.49Å; T160-G163 VanDerWaalsContact O-N 3.16Å; T160-W164 PolarHBondContact O-N 3.35Å
161H94.3Very high92.9Very high3 Ų329.3 Ų29.31%0.01414%0.14CC..Hα-helixtrans-74.9-27.4178.5-66.7-40.5000113.7H157 L158 G163 W164 A165 N322 L323 R381H157-H161 WeakPolarHBondContact O-CB 3.46Å; H157-H161 PolarHBondContact O-CD2 3.36Å; H157-H161 PolarHBondContact O-N 3.4Å; L158-H161 PolarHBondContact O-N 2.78Å; H161-G163 PolarHBondContact O-N 3.34Å; H161-W164 AromaticContact CE1-CE2 3.86Å; H161-W164 AromaticContact CE1-CH2 3.71Å; H161-W164 AromaticContact CE1-CZ2 3.66Å; H161-W164 AromaticContact CE1-CZ3 3.91Å; H161-W164 AromaticContact ND1-CD2 3.46Å; H161-W164 AromaticContact ND1-CE2 3.56Å; H161-W164 AromaticContact ND1-CE3 3.6Å; H161-W164 AromaticContact ND1-CZ2 3.84Å; H161-W164 AromaticContact ND1-CZ3 3.87Å; H161-W164 PolarHBondContact O-N 3.24Å; H161-A165 PolarHBondContact O-N 3.26Å; H161-N322 HydrophobicContact CB-CB 4.39Å; H161-L323 HydrophobicContact CB-CB 4.06Å; H161-L323 HydrophobicContact CB-CD1 4.41Å; H161-R381 PolarHBondContact CE1-NH1 3.14Å; H161-R381 VanDerWaalsContact NE2-CZ 3.3Å; H161-R381 PolarHBondContact NE2-NH1 3.01Å
162C95.7Very high92.8Very high35 Ų3524.2 Ų24.224%0.23612%0.121CC..Hα-helixtrans-59.2-41.4165.7-168.70000110.3M31 L158 L159 A165 W166 L323M31-C162 HydrophobicContact SD-CB 4.48Å; L158-C162 WeakPolarHBondContact O-CB 3.33Å; L158-C162 PolarHBondContact O-N 3.1Å; L159-C162 WeakPolarHBondContact O-CB 3.42Å; L159-C162 PolarHBondContact O-N 3.25Å; C162-A165 PolarHBondContact O-N 3.27Å; C162-W166 VanDerWaalsContact O-CD1 3.23Å; C162-W166 PolarHBondContact O-N 3.12Å; C162-W166 VanDerWaalsContact SG-CD1 3.59Å; C162-L323 HydrophobicContact CB-CD1 4.16Å
163G94.6Very high92.6Very high1 Ų125.6 Ų25.61%0.0114%0.137CC..Hα-helixtrans-61.7-44.2174.300000113.5M31 G35 L159 T160 H161 A165 W166 G167M31-G163 WeakPolarHBondContact O-CA 3.23Å; G35-G163 WeakPolarHBondContact CA-O 3.47Å; L159-G163 PolarHBondContact O-N 2.94Å; L159-G163 VanDerWaalsContact O-N 3.09Å; T160-G163 WeakPolarHBondContact O-CA 3.39Å; T160-G163 PolarHBondContact O-N 3.49Å; T160-G163 VanDerWaalsContact O-N 3.16Å; H161-G163 PolarHBondContact O-N 3.34Å; G163-A165 VanDerWaalsContact C-N 3.33Å; G163-A165 PolarHBondContact O-N 2.98Å; G163-W166 PolarHBondContact O-N 3.17Å; G163-G167 PolarHBondContact O-N 3.44Å
164W94.6Very high92.2Very high9 Ų927.8 Ų27.83%0.03415%0.151CC..Hα-helixtrans-57.4-47.7174-63.517.3000110.7M38 T160 H161 G167 F168 Y318 S319M38-W164 HydrophobicContact CB-CG 4.42Å; M38-W164 HydrophobicContact CE-CZ2 3.74Å; M38-W164 HydrophobicContact CG-CD2 4.01Å; M38-W164 HydrophobicContact CG-CG 4.05Å; M38-W164 HydrophobicContact CG-CZ2 4.32Å; M38-W164 HydrophobicContact SD-CZ2 4.17Å; T160-W164 PolarHBondContact O-N 3.35Å; H161-W164 AromaticContact CE1-CE2 3.86Å; H161-W164 AromaticContact CE1-CH2 3.71Å; H161-W164 AromaticContact CE1-CZ2 3.66Å; H161-W164 AromaticContact CE1-CZ3 3.91Å; H161-W164 AromaticContact ND1-CD2 3.46Å; H161-W164 AromaticContact ND1-CE2 3.56Å; H161-W164 AromaticContact ND1-CE3 3.6Å; H161-W164 AromaticContact ND1-CZ2 3.84Å; H161-W164 AromaticContact ND1-CZ3 3.87Å; H161-W164 PolarHBondContact O-N 3.24Å; W164-G167 PolarHBondContact O-N 2.98Å; W164-F168 WeakPolarHBondContact O-CD2 3.22Å; W164-F168 PolarHBondContact O-N 2.94Å; W164-Y318 HydrophobicContact CE3-CE1 4.49Å; W164-Y318 HydrophobicContact CZ3-CE1 4.03Å; W164-S319 WeakPolarHBondContact CB-OG 3.46Å
165A95.9Very high91.6Very high4 Ų427 Ų273%0.03315%0.146CC..Hα-helixtrans-61-52.2-179.600000111.7H161 C162 G163 G167 F168 L169 F316 L320H161-A165 PolarHBondContact O-N 3.26Å; C162-A165 PolarHBondContact O-N 3.27Å; G163-A165 VanDerWaalsContact C-N 3.33Å; G163-A165 PolarHBondContact O-N 2.98Å; A165-G167 VanDerWaalsContact C-N 3.28Å; A165-G167 PolarHBondContact O-N 3.48Å; A165-F168 PolarHBondContact O-N 3.18Å; A165-L169 VanDerWaalsContact O-CB 3.32Å; A165-L169 WeakPolarHBondContact O-CB 3.18Å; A165-L169 PolarHBondContact O-N 2.9Å; A165-F316 HydrophobicContact CB-CD2 3.87Å; A165-F316 HydrophobicContact CB-CE2 3.98Å; A165-F316 WeakPolarHBondContact O-CD2 3.27Å; A165-L320 HydrophobicContact CB-CD2 4.23Å
166W94.2Very high91.2Very high134 Ų13428.3 Ų28.351%0.50815%0.15SC..Hα-helixtrans-57.9-40.5176-78.7113.1000112.4C162 G163 L169 L170 W232C162-W166 VanDerWaalsContact O-CD1 3.23Å; C162-W166 PolarHBondContact O-N 3.12Å; C162-W166 VanDerWaalsContact SG-CD1 3.59Å; G163-W166 PolarHBondContact O-N 3.17Å; W166-L169 HydrophobicContact CE3-CD2 4.17Å; W166-L169 HydrophobicContact CZ3-CD2 4.14Å; W166-L169 PolarHBondContact O-N 3.12Å; W166-L170 WeakPolarHBondContact O-CG 3.38Å; W166-L170 PolarHBondContact O-N 3.39Å; W166-W232 HydrophobicContact CB-CH2 3.69Å; W166-W232 HydrophobicContact CB-CZ2 4.32Å
167G91.9Very high90.5Very high1 Ų129.8 Ų29.81%0.0117%0.167CC..Hα-helixtrans-61.3-49.4178.300000113.2G35 G163 W164 A165 S171G35-G167 VanDerWaalsContact O-CA 3.23Å; G35-G167 WeakPolarHBondContact O-CA 3.48Å; G163-G167 PolarHBondContact O-N 3.44Å; W164-G167 PolarHBondContact O-N 2.98Å; A165-G167 VanDerWaalsContact C-N 3.28Å; A165-G167 PolarHBondContact O-N 3.48Å; G167-S171 WeakPolarHBondContact O-CB 3.49Å; G167-S171 PolarHBondContact O-N 3.41Å; G167-S171 PolarHBondContact O-OG 3.02Å
168F93Very high89.7Confident3 Ų330.1 Ų30.11%0.01317%0.17CC..Hα-helixtrans-66.5-38176.7-74.3-63.1000112.2M38 P39 W164 A165 S171 A172 L315 F316 S319M38-F168 HydrophobicContact CB-CE2 4.18Å; M38-F168 HydrophobicContact CB-CZ 4.17Å; P39-F168 HydrophobicContact CB-CD1 4.04Å; P39-F168 HydrophobicContact CB-CE1 4.07Å; P39-F168 HydrophobicContact CG-CD1 4Å; P39-F168 HydrophobicContact CG-CE1 4.16Å; P39-F168 HydrophobicContact CG-CG 4.23Å; W164-F168 WeakPolarHBondContact O-CD2 3.22Å; W164-F168 PolarHBondContact O-N 2.94Å; A165-F168 PolarHBondContact O-N 3.18Å; F168-S171 PolarHBondContact O-N 2.99Å; F168-A172 VanDerWaalsContact O-CB 3.29Å; F168-A172 WeakPolarHBondContact O-CB 3.34Å; F168-A172 PolarHBondContact O-N 3.18Å; F168-L315 HydrophobicContact CB-CB 4.32Å; F168-L315 HydrophobicContact CD1-CB 3.54Å; F168-L315 HydrophobicContact CD1-CD1 3.96Å; F168-L315 HydrophobicContact CD1-CG 4.4Å; F168-L315 HydrophobicContact CD2-CB 3.88Å; F168-L315 HydrophobicContact CE1-CB 3.69Å; F168-L315 HydrophobicContact CE1-CD1 3.5Å; F168-L315 VanDerWaalsContact CE1-CD1 3.5Å; F168-L315 HydrophobicContact CE1-CG 4.15Å; F168-L315 HydrophobicContact CE2-CB 4.04Å; F168-L315 HydrophobicContact CG-CB 3.65Å; F168-L315 HydrophobicContact CZ-CB 3.95Å; F168-L315 HydrophobicContact CZ-CD1 4.06Å; F168-L315 HydrophobicContact CZ-CD2 4.49Å; F168-L315 HydrophobicContact CZ-CG 4.41Å; F168-F316 HydrophobicContact CB-CB 4.3Å; F168-S319 WeakPolarHBondContact CD2-OG 3.4Å
169L92.8Very high88.8Confident52 Ų5228.6 Ų28.627%0.27216%0.161SC..Hα-helixtrans-63.8-46.6178.3-17862.1000112.5A165 W166 A172 G173 Y313 F316A165-L169 VanDerWaalsContact O-CB 3.32Å; A165-L169 WeakPolarHBondContact O-CB 3.18Å; A165-L169 PolarHBondContact O-N 2.9Å; W166-L169 HydrophobicContact CE3-CD2 4.17Å; W166-L169 HydrophobicContact CZ3-CD2 4.14Å; W166-L169 PolarHBondContact O-N 3.12Å; L169-A172 PolarHBondContact O-N 3.12Å; L169-G173 PolarHBondContact O-N 3.1Å; L169-Y313 HydrophobicContact CD1-CE1 4.27Å; L169-F316 HydrophobicContact CB-CD2 3.82Å; L169-F316 HydrophobicContact CB-CE2 4.09Å; L169-F316 HydrophobicContact CB-CG 4.38Å; L169-F316 HydrophobicContact CD2-CE2 3.99Å; L169-F316 HydrophobicContact CD2-CZ 4.23Å; L169-F316 HydrophobicContact CG-CE2 4.44Å
170L90Very high87.9Confident60 Ų6029.3 Ų29.331%0.31417%0.17SC..Hα-helixtrans-68.1-37.9177.2-68.2-170.4000112.1W166 G173 T174 L228 W232W166-L170 WeakPolarHBondContact O-CG 3.38Å; W166-L170 PolarHBondContact O-N 3.39Å; L170-G173 PolarHBondContact O-N 2.72Å; L170-T174 PolarHBondContact O-N 3.43Å; L170-T174 PolarHBondContact O-OG1 3.35Å; L170-L228 HydrophobicContact CB-CD2 4.11Å; L170-L228 HydrophobicContact CD1-CD1 3.94Å; L170-L228 HydrophobicContact CD1-CD2 3.99Å; L170-L228 HydrophobicContact CD1-CG 4.45Å; L170-W232 HydrophobicContact CD1-CH2 3.83Å; L170-W232 HydrophobicContact CD1-CZ2 3.33Å; L170-W232 HydrophobicContact CG-CH2 4.47Å; L170-W232 HydrophobicContact CG-CZ2 4.34Å
171S85.8Confident87.1Confident4 Ų433.5 Ų33.53%0.02820%0.195CC..Hα-helixtrans-62-46.1174.3-55.30000111.5P39 Y43 G167 F168 G173 T174 L175 Y229P39-S171 WeakPolarHBondContact CB-OG 3.42Å; Y43-S171 VanDerWaalsContact CE2-CB 3.46Å; G167-S171 WeakPolarHBondContact O-CB 3.49Å; G167-S171 PolarHBondContact O-N 3.41Å; G167-S171 PolarHBondContact O-OG 3.02Å; F168-S171 PolarHBondContact O-N 2.99Å; S171-G173 VanDerWaalsContact C-N 3.32Å; S171-G173 PolarHBondContact O-N 2.86Å; S171-T174 PolarHBondContact O-N 3.42Å; S171-T174 PolarHBondContact O-OG1 3.27Å; S171-L175 WeakPolarHBondContact O-CB 3.4Å; S171-L175 WeakPolarHBondContact O-CD1 3.28Å; S171-L175 WeakPolarHBondContact O-CG 3.5Å; S171-L175 PolarHBondContact O-N 3.39Å; S171-Y229 PolarHBondContact OG-OH 2.92Å
172A87.6Confident85.9Confident0 Ų036 Ų360%021%0.211CC..Hα-helixtrans-59.6-42.9175.700000111.6F168 L169 L175 H176 Y313F168-A172 VanDerWaalsContact O-CB 3.29Å; F168-A172 WeakPolarHBondContact O-CB 3.34Å; F168-A172 PolarHBondContact O-N 3.18Å; L169-A172 PolarHBondContact O-N 3.12Å; A172-L175 PolarHBondContact O-N 3.4Å; A172-H176 VanDerWaalsContact O-CB 3.25Å; A172-H176 WeakPolarHBondContact O-CB 3.39Å; A172-H176 PolarHBondContact O-N 2.99Å; A172-Y313 HydrophobicContact CB-CD1 3.78Å; A172-Y313 HydrophobicContact CB-CD2 4.12Å; A172-Y313 HydrophobicContact CB-CE1 3.65Å; A172-Y313 HydrophobicContact CB-CE2 3.99Å; A172-Y313 HydrophobicContact CB-CG 4Å
173G86.6Confident84.5Confident36 Ų3641.1 Ų41.137%0.37124%0.236SC..Hα-helixtrans-64.5-43.8178.400000114L169 L170 S171 H176 G177L169-G173 PolarHBondContact O-N 3.1Å; L170-G173 PolarHBondContact O-N 2.72Å; S171-G173 VanDerWaalsContact C-N 3.32Å; S171-G173 PolarHBondContact O-N 2.86Å; G173-H176 PolarHBondContact O-N 3.4Å; G173-G177 PolarHBondContact O-N 2.83Å; G173-G177 VanDerWaalsContact O-N 3.09Å
174T83.4Confident83.1Confident50 Ų5044.2 Ų44.231%0.30725%0.25SS..Hα-helixtrans-66.4-40176.555.30000111.7L170 S171 I178L170-T174 PolarHBondContact O-N 3.43Å; L170-T174 PolarHBondContact O-OG1 3.35Å; S171-T174 PolarHBondContact O-N 3.42Å; S171-T174 PolarHBondContact O-OG1 3.27Å; T174-I178 WeakPolarHBondContact O-CG1 3.48Å; T174-I178 PolarHBondContact O-N 2.63Å
175L80Confident81.5Confident2 Ų246.3 Ų46.31%0.0126%0.264CS..Hα-helixtrans-64.4-44.9174.4-77.2162.6000112.7Y43 S171 A172 G177 I178 E179 L217 Q308Y43-L175 HydrophobicContact CD1-CD1 4.26Å; Y43-L175 HydrophobicContact CE1-CD1 3.49Å; Y43-L175 VanDerWaalsContact CE1-CD1 3.49Å; Y43-L175 HydrophobicContact CE2-CD1 4.36Å; S171-L175 WeakPolarHBondContact O-CB 3.4Å; S171-L175 WeakPolarHBondContact O-CD1 3.28Å; S171-L175 WeakPolarHBondContact O-CG 3.5Å; S171-L175 PolarHBondContact O-N 3.39Å; A172-L175 PolarHBondContact O-N 3.4Å; L175-G177 VanDerWaalsContact C-N 3.31Å; L175-G177 PolarHBondContact O-N 3.35Å; L175-I178 WeakPolarHBondContact O-CB 3.16Å; L175-I178 PolarHBondContact O-N 2.87Å; L175-I178 VanDerWaalsContact O-N 3.12Å; L175-E179 WeakPolarHBondContact O-CG 3.19Å; L175-E179 PolarHBondContact O-N 3.14Å; L175-L217 HydrophobicContact CD1-CD1 4.48Å; L175-L217 HydrophobicContact CD2-CD1 3.77Å; L175-L217 HydrophobicContact CD2-CG 3.81Å; L175-L217 HydrophobicContact CG-CD1 4.14Å; L175-L217 HydrophobicContact CG-CG 4.35Å; L175-Q308 HydrophobicContact CD1-CG 3.79Å; L175-Q308 HydrophobicContact CD2-CB 4.29Å; L175-Q308 HydrophobicContact CD2-CG 3.8Å; L175-Q308 HydrophobicContact CG-CG 4.38Å
176H83.7Confident80Confident83 Ų8353 Ų5338%0.38429%0.294SS..Hα-helixtrans-64.2-37.1180-173.258.1000112.1A172 G173 E179 S180A172-H176 VanDerWaalsContact O-CB 3.25Å; A172-H176 WeakPolarHBondContact O-CB 3.39Å; A172-H176 PolarHBondContact O-N 2.99Å; G173-H176 PolarHBondContact O-N 3.4Å; H176-E179 IonicContact ND1-OE2 2.74Å; H176-S180 VanDerWaalsContact O-CB 3.3Å; H176-S180 WeakPolarHBondContact O-CB 3.38Å; H176-S180 PolarHBondContact O-N 3.02Å; H176-S180 PolarHBondContact O-OG 2.96Å
177G79.3Confident79Confident38 Ų3851.8 Ų51.839%0.39230%0.295SS..Hα-helixtrans-60.6-42.6171.400000112.7G173 L175 T181G173-G177 PolarHBondContact O-N 2.83Å; G173-G177 VanDerWaalsContact O-N 3.09Å; L175-G177 VanDerWaalsContact C-N 3.31Å; L175-G177 PolarHBondContact O-N 3.35Å; G177-T181 WeakPolarHBondContact O-CG2 3.33Å; G177-T181 PolarHBondContact O-N 3.45Å; G177-T181 PolarHBondContact O-OG1 3.28Å
178I75.9Confident78.1Confident23 Ų2353.2 Ų53.212%0.11831%0.305CS..Hα-helixtrans-63.4-55175.9-70.1165.5000110.8T174 L175 S180 T181 T182 L217 V220T174-I178 WeakPolarHBondContact O-CG1 3.48Å; T174-I178 PolarHBondContact O-N 2.63Å; L175-I178 WeakPolarHBondContact O-CB 3.16Å; L175-I178 PolarHBondContact O-N 2.87Å; L175-I178 VanDerWaalsContact O-N 3.12Å; I178-S180 PolarHBondContact O-N 3.28Å; I178-T181 WeakPolarHBondContact O-CA 3.44Å; I178-T181 PolarHBondContact O-N 3.4Å; I178-T181 PolarHBondContact O-OG1 3.42Å; I178-T182 PolarHBondContact O-N 2.9Å; I178-T182 VanDerWaalsContact O-N 3.07Å; I178-T182 PolarHBondContact O-OG1 2.98Å; I178-L217 HydrophobicContact CD1-CD2 4.18Å; I178-L217 HydrophobicContact CD1-CG 4.43Å; I178-V220 HydrophobicContact CB-CG2 4.24Å; I178-V220 HydrophobicContact CG1-CB 4.24Å; I178-V220 HydrophobicContact CG1-CG2 3.87Å; I178-V220 HydrophobicContact CG2-CG2 3.74Å
179E75.6Confident77.1Confident13 Ų1354.1 Ų54.16%0.06131%0.308CS..Hα-helixtrans-54.7-36.1178.8-69.1167.2176.100112.6L175 H176 T182 N183 E184 T185 P307 Q308 S309L175-E179 WeakPolarHBondContact O-CG 3.19Å; L175-E179 PolarHBondContact O-N 3.14Å; H176-E179 IonicContact ND1-OE2 2.74Å; E179-T182 PolarHBondContact O-OG1 3.07Å; E179-N183 PolarHBondContact O-N 3.42Å; E179-E184 PolarHBondContact O-N 2.94Å; E179-E184 VanDerWaalsContact O-N 3.11Å; E179-T185 HydrophobicContact CB-CG2 4.17Å; E179-T185 WeakPolarHBondContact O-CG2 3.41Å; E179-P307 VanDerWaalsContact CD-CB 3.47Å; E179-P307 HydrophobicContact CG-CB 4.5Å; E179-P307 VanDerWaalsContact OE1-CB 3.24Å; E179-P307 WeakPolarHBondContact OE1-CB 3.47Å; E179-P307 WeakPolarHBondContact OE2-CB 3.46Å; E179-Q308 WeakPolarHBondContact OE1-CA 3.38Å; E179-Q308 PolarHBondContact OE1-N 2.97Å; E179-S309 PolarHBondContact OE1-N 2.94Å; E179-S309 PolarHBondContact OE1-OG 3.33Å; E179-S309 WeakPolarHBondContact OE2-CB 3.17Å; E179-S309 PolarHBondContact OE2-OG 3.1Å
180S78Confident76.2Confident57 Ų5752.1 Ų52.140%0.39930%0.298SS..Hα-helixtrans-71.1-29.1176.9-58.90000113H176 I178H176-S180 VanDerWaalsContact O-CB 3.3Å; H176-S180 WeakPolarHBondContact O-CB 3.38Å; H176-S180 PolarHBondContact O-N 3.02Å; H176-S180 PolarHBondContact O-OG 2.96Å; I178-S180 PolarHBondContact O-N 3.28Å
181T75.5Confident75.1Confident95 Ų9554.9 Ų54.958%0.58331%0.313SS*.Hα-helixtrans-82.5-25.5175.256.70000113.7G177 I178G177-T181 WeakPolarHBondContact O-CG2 3.33Å; G177-T181 PolarHBondContact O-N 3.45Å; G177-T181 PolarHBondContact O-OG1 3.28Å; I178-T181 WeakPolarHBondContact O-CA 3.44Å; I178-T181 PolarHBondContact O-N 3.4Å; I178-T181 PolarHBondContact O-OG1 3.42Å
182T68.8Low74.1Confident57 Ų5755.6 Ų55.635%0.3532%0.319SS..Hα-helixtrans-93.9-3.2-178.8560000114I178 E179 E184I178-T182 PolarHBondContact O-N 2.9Å; I178-T182 VanDerWaalsContact O-N 3.07Å; I178-T182 PolarHBondContact O-OG1 2.98Å; E179-T182 PolarHBondContact O-OG1 3.07Å; T182-E184 WeakPolarHBondContact CB-OE2 3.12Å; T182-E184 PolarHBondContact O-N 3.17Å; T182-E184 WeakPolarHBondContact OG1-CB 3.4Å; T182-E184 VanDerWaalsContact OG1-CG 3.32Å; T182-E184 WeakPolarHBondContact OG1-CG 3.31Å; T182-E184 PolarHBondContact OG1-OE2 3.41Å
183N67.4Low73Confident142 Ų14261 Ų6176%0.75935%0.347SS*.THydrogen-bonded Turntrans58.820.2-167.7-66.4-38.6000114E179 T185E179-N183 PolarHBondContact O-N 3.42Å; N183-T185 VanDerWaalsContact C-N 3.29Å; N183-T185 PolarHBondContact O-N 3.4Å
184E64.7Low71.9Confident66 Ų6663.3 Ų63.331%0.30836%0.357SS..  trans-85.93.6-177.6-68.4173.9128.300113.6E179 T182 H186 M187E179-E184 PolarHBondContact O-N 2.94Å; E179-E184 VanDerWaalsContact O-N 3.11Å; T182-E184 WeakPolarHBondContact CB-OE2 3.12Å; T182-E184 PolarHBondContact O-N 3.17Å; T182-E184 WeakPolarHBondContact OG1-CB 3.4Å; T182-E184 VanDerWaalsContact OG1-CG 3.32Å; T182-E184 WeakPolarHBondContact OG1-CG 3.31Å; T182-E184 PolarHBondContact OG1-OE2 3.41Å; E184-H186 PolarHBondContact O-N 3.36Å; E184-M187 PolarHBondContact O-N 3.06Å
185T62.5Low71.2Confident52 Ų5267 Ų6732%0.31938%0.375SS..THydrogen-bonded Turntrans-55.3-4.1-18062.90000115.8E179 N183 P307E179-T185 HydrophobicContact CB-CG2 4.17Å; E179-T185 WeakPolarHBondContact O-CG2 3.41Å; N183-T185 VanDerWaalsContact C-N 3.29Å; N183-T185 PolarHBondContact O-N 3.4Å; T185-P307 WeakPolarHBondContact O-CG 3.39Å
186H64.2Low71.1Confident144 Ų14473 Ų7367%0.66740%0.398SS*.THydrogen-bonded Turntrans-116-9.1177.7-66.4-12.8000114.6E184E184-H186 PolarHBondContact O-N 3.36Å
187M71.6Confident71.1Confident109 Ų10971.1 Ų71.154%0.53739%0.389SS..SBendtrans-82.2137.4179.1-65.7-105.2-136.400111.2E184E184-M187 PolarHBondContact O-N 3.06Å
188P73.2Confident71.4Confident32 Ų3269.3 Ų69.321%0.20837%0.37CS..  trans-73.4138.3166.231.8-32.7000109.6T190 L191P188-T190 PolarHBondContact O-N 3.28Å; P188-L191 HydrophobicContact CG-CD1 4.44Å
189W73.7Confident71.9Confident21 Ų2171.1 Ų71.18%0.0838%0.375CS..SBendtrans-62.6-40.2-178.7179.522.1000112.6Y43 L46 A303 S306 Q308 V311Y43-W189 AromaticContact CD1-CH2 3.72Å; Y43-W189 HydrophobicContact CD1-CH2 3.72Å; Y43-W189 AromaticContact CD1-CZ3 3.9Å; Y43-W189 HydrophobicContact CD1-CZ3 3.9Å; Y43-W189 HydrophobicContact CE1-CZ3 4.47Å; L46-W189 HydrophobicContact CB-CE3 4.44Å; L46-W189 HydrophobicContact CB-CH2 3.33Å; L46-W189 HydrophobicContact CB-CZ2 4.09Å; L46-W189 HydrophobicContact CB-CZ3 3.55Å; L46-W189 HydrophobicContact CD1-CH2 4.12Å; L46-W189 HydrophobicContact CD1-CZ3 3.64Å; L46-W189 HydrophobicContact CG-CH2 4.35Å; L46-W189 HydrophobicContact CG-CZ3 4.18Å; W189-A303 HydrophobicContact CB-CB 4.29Å; W189-A303 HydrophobicContact CE3-CB 4.09Å; W189-A303 PolarHBondContact N-O 3.31Å; W189-A303 VanDerWaalsContact N-O 3.08Å; W189-S306 PolarHBondContact N-O 3Å; W189-Q308 HydrophobicContact CB-CB 4.27Å; W189-Q308 HydrophobicContact CD2-CB 3.89Å; W189-Q308 HydrophobicContact CD2-CG 3.68Å; W189-Q308 HydrophobicContact CE3-CB 4Å; W189-Q308 HydrophobicContact CE3-CG 3.59Å; W189-Q308 HydrophobicContact CG-CB 4.02Å; W189-Q308 HydrophobicContact CG-CG 4.31Å; W189-Q308 HydrophobicContact CH2-CG 3.98Å; W189-Q308 HydrophobicContact CZ2-CG 4.07Å; W189-Q308 HydrophobicContact CZ3-CG 3.73Å; W189-V311 HydrophobicContact CE3-CG2 4.2Å; W189-V311 HydrophobicContact CZ3-CG2 4.41Å
190T71.9Confident72.3Confident11 Ų1173.7 Ų73.77%0.06739%0.387CS..SBendtrans-106.2114.8173.7520000110.6P188 A192 Q299 A303 C304P188-T190 PolarHBondContact O-N 3.28Å; T190-A192 PolarHBondContact O-N 2.96Å; T190-Q299 HydrophobicContact CG2-CG 4.08Å; T190-A303 HydrophobicContact CG2-CB 4.13Å; T190-A303 PolarHBondContact N-O 3.36Å; T190-A303 WeakPolarHBondContact OG1-CB 3.44Å; T190-A303 PolarHBondContact OG1-O 3.09Å; T190-C304 WeakPolarHBondContact OG1-CA 3.33Å; T190-C304 PolarHBondContact OG1-N 3.39Å; T190-C304 VanDerWaalsContact OG1-N 3.15Å; T190-C304 PolarHBondContact OG1-SG 2.95Å; T190-C304 VanDerWaalsContact OG1-SG 3.4Å
191L67.3Low72.6Confident118 Ų11872.2 Ų72.262%0.61837%0.373SS*.  trans-72.597.5-179.7-15687.6000111.3P188 V208P188-L191 HydrophobicContact CG-CD1 4.44Å; L191-V208 HydrophobicContact CB-CG1 4Å; L191-V208 HydrophobicContact CB-CG2 4.39Å; L191-V208 HydrophobicContact CD2-CB 4.49Å; L191-V208 HydrophobicContact CD2-CG1 3.85Å; L191-V208 HydrophobicContact CD2-CG2 3.76Å
192A65.4Low72.9Confident19 Ų1972.3 Ų72.316%0.15737%0.367CS..  trans-110.7134171.700000111T190 K197 Y201 C304T190-A192 PolarHBondContact O-N 2.96Å; A192-K197 HydrophobicContact CB-CG 4.06Å; A192-K197 VanDerWaalsContact O-CE 3.23Å; A192-K197 WeakPolarHBondContact O-CE 3.49Å; A192-Y201 HydrophobicContact CB-CD2 4.24Å; A192-Y201 HydrophobicContact CB-CE2 4.31Å; A192-C304 HydrophobicContact CB-CB 4.18Å
193L65.3Low72.8Confident112 Ų11271 Ų7159%0.58636%0.356SS*.  trans-52.3146.6164.7-66.6167.6000109.6D195 R196L193-D195 PolarHBondContact O-N 3.07Å; L193-D195 VanDerWaalsContact O-N 3.11Å; L193-R196 HydrophobicContact CB-CG 4.46Å; L193-R196 PolarHBondContact O-N 3.37Å
194S63.3Low72.3Confident85 Ų8567.1 Ų67.159%0.59435%0.35SS*.G310 helixtrans-42.4-48.317741.70000112.5R196S194-R196 PolarHBondContact O-N 2.92Å
195D68.8Low71.5Confident127 Ų12767.1 Ų67.168%0.67936%0.358SS*.G310 helixtrans-79.2-1.7-170.3-45.1-4.2000112.7L193L193-D195 PolarHBondContact O-N 3.07Å; L193-D195 VanDerWaalsContact O-N 3.11Å
196R77.2Confident70.8Confident130 Ų13074.1 Ų74.149%0.49138%0.384SS..G310 helixtrans-124.535.4-176.7-59.5-169.3-176.2-169.82.1112.5L193 S194 Y201L193-R196 HydrophobicContact CB-CG 4.46Å; L193-R196 PolarHBondContact O-N 3.37Å; S194-R196 PolarHBondContact O-N 2.92Å; R196-Y201 VanDerWaalsContact O-CA 3.23Å; R196-Y201 WeakPolarHBondContact O-CA 3.24Å; R196-Y201 WeakPolarHBondContact O-CD2 3.17Å
197K83Confident69.6Low43 Ų4374.1 Ų74.119%0.18739%0.389CS..SBendtrans-105163.5173.1-54.9-168.4-176.6-166.60111.4A192 R199 H200 C304 V305 P361A192-K197 HydrophobicContact CB-CG 4.06Å; A192-K197 VanDerWaalsContact O-CE 3.23Å; A192-K197 WeakPolarHBondContact O-CE 3.49Å; K197-R199 PolarHBondContact O-N 3.13Å; K197-H200 PolarHBondContact O-N 2.92Å; K197-C304 HydrophobicContact CB-CB 4.48Å; K197-C304 HydrophobicContact CD-CB 4.11Å; K197-C304 VanDerWaalsContact CE-O 3.29Å; K197-C304 WeakPolarHBondContact CE-O 3.28Å; K197-C304 HydrophobicContact CG-CB 4.12Å; K197-C304 PolarHBondContact NZ-O 3.16Å; K197-V305 HydrophobicContact CD-CG2 3.96Å; K197-P361 HydrophobicContact CB-CG 3.94Å
198G86Confident68.2Low0 Ų072.1 Ų72.10%038%0.383CS..G310 helixtrans55.4-129.7-178.700000112.3H200 Y201 A300 Y301G198-H200 PolarHBondContact O-N 3.37Å; G198-H200 VanDerWaalsContact O-N 3.08Å; G198-Y201 WeakPolarHBondContact O-CB 3.41Å; G198-Y201 PolarHBondContact O-N 3.37Å; G198-A300 WeakPolarHBondContact CA-O 3.16Å; G198-A300 PolarHBondContact N-O 3.45Å; G198-Y301 VanDerWaalsContact CA-CZ 3.48Å
199R86.1Confident66.3Low61 Ų6175 Ų7523%0.2341%0.408CS..G310 helixtrans-53.4-32.4-179.274.6-169.8-171.7175.42.1114.2K197 Y201 Y301 W357 E427 I430K197-R199 PolarHBondContact O-N 3.13Å; R199-Y201 VanDerWaalsContact C-N 3.34Å; R199-Y301 PolarHBondContact N-OH 3.39Å; R199-Y301 VanDerWaalsContact N-OH 3.15Å; R199-W357 WeakPolarHBondContact CD-O 3.37Å; R199-W357 PolarHBondContact NH1-O 3.42Å; R199-E427 HydrophobicContact CB-CB 4.39Å; R199-E427 HydrophobicContact CB-CG 4.46Å; R199-E427 PolarHBondContact O-N 3.2Å; R199-I430 HydrophobicContact CB-CD1 4.3Å
200H85Confident64.7Low67 Ų6780.9 Ų80.931%0.3144%0.442SS..G310 helixtrans-87-1.1-178.1-67.3-37.6000114K197 G198 E427K197-H200 PolarHBondContact O-N 2.92Å; G198-H200 PolarHBondContact O-N 3.37Å; G198-H200 VanDerWaalsContact O-N 3.08Å; H200-E427 IonicContact CE1-OE2 3.75Å; H200-E427 IonicContact ND1-OE2 3.92Å
201Y84.3Confident63.2Low25 Ų2587.6 Ų87.610%0.09847%0.472CS..  trans-63.9138.2173.9-176.9-98.8000111.7A192 R196 G198 R199 E203 Q299 A300 C304 K425 T426A192-Y201 HydrophobicContact CB-CD2 4.24Å; A192-Y201 HydrophobicContact CB-CE2 4.31Å; R196-Y201 VanDerWaalsContact O-CA 3.23Å; R196-Y201 WeakPolarHBondContact O-CA 3.24Å; R196-Y201 WeakPolarHBondContact O-CD2 3.17Å; G198-Y201 WeakPolarHBondContact O-CB 3.41Å; G198-Y201 PolarHBondContact O-N 3.37Å; R199-Y201 VanDerWaalsContact C-N 3.34Å; Y201-E203 HydrophobicContact CE1-CB 4.47Å; Y201-Q299 HydrophobicContact CE1-CB 4.39Å; Y201-Q299 HydrophobicContact CE1-CG 4Å; Y201-Q299 PolarHBondContact OH-NE2 3.16Å; Y201-A300 HydrophobicContact CD1-CB 3.83Å; Y201-A300 HydrophobicContact CG-CB 3.87Å; Y201-C304 WeakPolarHBondContact CD2-SG 3.25Å; Y201-C304 WeakPolarHBondContact CE2-SG 3.29Å; Y201-K425 WeakPolarHBondContact O-CA 3.33Å; Y201-T426 PolarHBondContact O-N 3.42Å; Y201-T426 PolarHBondContact O-OG1 3.05Å; Y201-T426 VanDerWaalsContact O-OG1 3.12Å
202Q80.1Confident62.1Low97 Ų9784.5 Ų84.545%0.45346%0.456SS..BIsolated β-bridgetrans-143.9122.2176.3179.5176.6-10.300109.3G204 K425Q202-G204 PolarHBondContact O-N 2.92Å; Q202-K425 HydrophobicContact CB-CG 4.31Å
203E68.6Low61Low29 Ų2985.9 Ų85.914%0.13646%0.463CS..SBendtrans-68.4122.1171.2-168.7151.7-116.600108.4Y201 Q299 K421Y201-E203 HydrophobicContact CE1-CB 4.47Å; E203-Q299 PolarHBondContact OE1-NE2 3.07Å; E203-Q299 PolarHBondContact OE1-OE1 2.85Å; E203-K421 IonicContact OE1-NZ 3.96Å; E203-K421 PolarHBondContact OE1-NZ 3.02Å; E203-K421 IonicContact OE2-NZ 2.67Å; E203-K421 PolarHBondContact OE2-NZ 2.97Å
204G55.9Low60.2Low61 Ų6181.9 Ų81.963%0.62944%0.44SS*.  trans1406.4-177.200000118.3Q202 K206Q202-G204 PolarHBondContact O-N 2.92Å; G204-K206 PolarHBondContact O-N 3.17Å; G204-K206 VanDerWaalsContact O-N 3.14Å
205S47.8Very low59.3Low67 Ų6780.6 Ų80.647%0.46943%0.43SS..  trans-73.1101.2169.9-169.30000110.7N207S205-N207 PolarHBondContact O-N 3.01Å
206K47.1Very low57.9Low199 Ų19975.3 Ų75.387%0.86541%0.405SS*.THydrogen-bonded Turntrans-66.4-0.6-176.3-64.9-175.4177.5-178.30115.2G204G204-K206 PolarHBondContact O-N 3.17Å; G204-K206 VanDerWaalsContact O-N 3.14Å
207N39.9Very low56.4Low144 Ų14470 Ų7077%0.7739%0.386SS*.THydrogen-bonded Turntrans-10212.4-163.3-64.417.2000114.3S205S205-N207 PolarHBondContact O-N 3.01Å
208V41.7Very low54.4Low67 Ų6769.3 Ų69.341%0.40639%0.391SS..  trans-129.183.7175.6-169.70000109.8L191 N210L191-V208 HydrophobicContact CB-CG1 4Å; L191-V208 HydrophobicContact CB-CG2 4.39Å; L191-V208 HydrophobicContact CD2-CB 4.49Å; L191-V208 HydrophobicContact CD2-CG1 3.85Å; L191-V208 HydrophobicContact CD2-CG2 3.76Å; V208-N210 HydrophobicContact CG1-CB 4.29Å; V208-N210 PolarHBondContact O-N 3.07Å
209A34.3Very low52.4Low91 Ų9173 Ų7375%0.75242%0.421SS*.  trans-88.117.7171.700000112.7Q211A209-Q211 PolarHBondContact O-N 3.43Å
210N39Very low50.7Low146 Ų14673.1 Ų73.178%0.78143%0.429SS*.  trans-73.9102.1175.4-84.325.6000109.7V208 I212V208-N210 HydrophobicContact CG1-CB 4.29Å; V208-N210 PolarHBondContact O-N 3.07Å; N210-I212 PolarHBondContact O-N 3.06Å
211Q40.9Very low49.3Very low151 Ų15173.7 Ų73.771%0.70643%0.434SS*.  trans-75.875.9-158.6-171.5-172.7-26.600113.6A209 T213A209-Q211 PolarHBondContact O-N 3.43Å; Q211-T213 HydrophobicContact CG-CG2 3.88Å; Q211-T213 WeakPolarHBondContact CG-OG1 3.36Å; Q211-T213 PolarHBondContact NE2-OG1 3.12Å; Q211-T213 PolarHBondContact O-N 2.81Å
212I45.3Very low48.3Very low53 Ų5374 Ų7427%0.27244%0.44SS..  trans-80.467.4155.5-48.5-176.5000108.5P48 N210 A216P48-I212 VanDerWaalsContact CG-O 3.28Å; P48-I212 WeakPolarHBondContact CG-O 3.43Å; N210-I212 PolarHBondContact O-N 3.06Å; I212-A216 HydrophobicContact CG2-CB 3.97Å
213T42.1Very low47.8Very low49 Ų4977.2 Ų77.230%0.30145%0.447SS..  trans-64.3172.1162.530.80000110.2Q211 S215 A216Q211-T213 HydrophobicContact CG-CG2 3.88Å; Q211-T213 WeakPolarHBondContact CG-OG1 3.36Å; Q211-T213 PolarHBondContact NE2-OG1 3.12Å; Q211-T213 PolarHBondContact O-N 2.81Å; T213-S215 WeakPolarHBondContact CB-OG 3.26Å; T213-S215 CarbonylContact O-C 3.58Å; T213-S215 PolarHBondContact O-N 3.49Å; T213-S215 PolarHBondContact O-OG 3.29Å; T213-S215 PolarHBondContact OG1-OG 2.95Å; T213-A216 PolarHBondContact O-N 2.85Å
214W48.3Very low47.9Very low28 Ų2884.2 Ų84.211%0.10647%0.474CS..THydrogen-bonded Turntrans-54.5-8.3169.2-91.684000114.8L40 S47 V100 A216 L217 G218L40-W214 HydrophobicContact CD1-CH2 4.1Å; S47-W214 PolarHBondContact OG-NE1 3.26Å; V100-W214 HydrophobicContact CG1-CD2 4.31Å; V100-W214 HydrophobicContact CG1-CH2 4.28Å; V100-W214 HydrophobicContact CG1-CZ2 4.04Å; W214-A216 PolarHBondContact O-N 3.44Å; W214-L217 HydrophobicContact CE3-CB 4.11Å; W214-L217 HydrophobicContact CE3-CD1 4.02Å; W214-L217 HydrophobicContact CH2-CD1 4.27Å; W214-L217 HydrophobicContact CZ3-CB 4.36Å; W214-L217 HydrophobicContact CZ3-CD1 3.54Å; W214-L217 PolarHBondContact O-N 2.93Å; W214-G218 PolarHBondContact O-N 3.01Å
215S43.2Very low48.6Very low57 Ų5782 Ų8240%0.39945%0.449SS..Hα-helixtrans-49.9-11.8157.259.20000115.3T213 G218 A219T213-S215 WeakPolarHBondContact CB-OG 3.26Å; T213-S215 CarbonylContact O-C 3.58Å; T213-S215 PolarHBondContact O-N 3.49Å; T213-S215 PolarHBondContact O-OG 3.29Å; T213-S215 PolarHBondContact OG1-OG 2.95Å; S215-G218 CarbonylContact O-C 3.36Å; S215-G218 PolarHBondContact O-N 3.31Å; S215-A219 VanDerWaalsContact O-CA 3.26Å; S215-A219 WeakPolarHBondContact O-CA 3.41Å; S215-A219 WeakPolarHBondContact O-CB 3.42Å; S215-A219 PolarHBondContact O-N 3.24Å
216A40.7Very low49.9Very low17 Ų1781.7 Ų81.714%0.1444%0.44CS..Hα-helixtrans-65.6-58.1167.100000111.2I212 T213 W214 G218 A219I212-A216 HydrophobicContact CG2-CB 3.97Å; T213-A216 PolarHBondContact O-N 2.85Å; W214-A216 PolarHBondContact O-N 3.44Å; A216-G218 PolarHBondContact O-N 2.87Å; A216-G218 VanDerWaalsContact O-N 3.15Å; A216-A219 PolarHBondContact O-N 2.96Å
217L44.8Very low51.6Low17 Ų1776 Ų769%0.08943%0.426CS..Hα-helixtrans-64.1-14.3170.1-96.1155.8000113.1L175 I178 W214 A225L175-L217 HydrophobicContact CD1-CD1 4.48Å; L175-L217 HydrophobicContact CD2-CD1 3.77Å; L175-L217 HydrophobicContact CD2-CG 3.81Å; L175-L217 HydrophobicContact CG-CD1 4.14Å; L175-L217 HydrophobicContact CG-CG 4.35Å; I178-L217 HydrophobicContact CD1-CD2 4.18Å; I178-L217 HydrophobicContact CD1-CG 4.43Å; W214-L217 HydrophobicContact CE3-CB 4.11Å; W214-L217 HydrophobicContact CE3-CD1 4.02Å; W214-L217 HydrophobicContact CH2-CD1 4.27Å; W214-L217 HydrophobicContact CZ3-CB 4.36Å; W214-L217 HydrophobicContact CZ3-CD1 3.54Å; W214-L217 PolarHBondContact O-N 2.93Å; L217-A225 HydrophobicContact CD2-CB 4.12Å
218G42.2Very low53.7Low29 Ų2971.8 Ų71.830%0.29940%0.403SS..Hα-helixtrans-101.1-6.8174.100000117W214 S215 A216 P222W214-G218 PolarHBondContact O-N 3.01Å; S215-G218 CarbonylContact O-C 3.36Å; S215-G218 PolarHBondContact O-N 3.31Å; A216-G218 PolarHBondContact O-N 2.87Å; A216-G218 VanDerWaalsContact O-N 3.15Å; G218-P222 WeakPolarHBondContact O-CD 3.38Å
219A43.7Very low55.8Low77 Ų7769.6 Ų69.664%0.63639%0.387SS*.Hα-helixtrans-81.6-41-172.200000111.6S215 A216S215-A219 VanDerWaalsContact O-CA 3.26Å; S215-A219 WeakPolarHBondContact O-CA 3.41Å; S215-A219 WeakPolarHBondContact O-CB 3.42Å; S215-A219 PolarHBondContact O-N 3.24Å; A216-A219 PolarHBondContact O-N 2.96Å
220V49Very low58.3Low64 Ų6468 Ų6839%0.38836%0.363SS..SBendtrans-100.6-21.8-170.5-147.40000112.6I178I178-V220 HydrophobicContact CB-CG2 4.24Å; I178-V220 HydrophobicContact CG1-CB 4.24Å; I178-V220 HydrophobicContact CG1-CG2 3.87Å; I178-V220 HydrophobicContact CG2-CG2 3.74Å
221N57Low60.8Low79 Ų7963 Ų6342%0.42235%0.346SS..  trans170114.1148.5-103.3-74.1000110.5W223 Y224N221-W223 PolarHBondContact O-N 3.5Å; N221-Y224 HydrophobicContact CB-CD2 3.52Å; N221-Y224 HydrophobicContact CB-CE2 3.7Å
222P62.2Low63.2Low33 Ų3357.7 Ų57.721%0.21432%0.32CS..Hα-helixtrans-66.5-23.5179.527.5-32.4000112.5I101 G218 Y224 A225 F226I101-P222 HydrophobicContact CG2-CB 4.41Å; G218-P222 WeakPolarHBondContact O-CD 3.38Å; P222-Y224 VanDerWaalsContact C-N 3.32Å; P222-Y224 PolarHBondContact O-N 3.07Å; P222-A225 PolarHBondContact O-N 3.5Å; P222-F226 WeakPolarHBondContact O-CB 3.09Å; P222-F226 PolarHBondContact O-N 2.83Å
223W69Low65.4Low163 Ų16355.1 Ų55.162%0.61731%0.307SS*.Hα-helixtrans-63.7-30.8-175.2-56.3115.9000113.9N221 S227N221-W223 PolarHBondContact O-N 3.5Å; W223-S227 VanDerWaalsContact O-CB 3.27Å; W223-S227 WeakPolarHBondContact O-CB 3.42Å; W223-S227 PolarHBondContact O-N 3.42Å
224Y72.6Confident67.8Low176 Ų17654.2 Ų54.269%0.6931%0.307SS*.Hα-helixtrans-69.3-46.7176.8-68.4-65.2000111.8N221 P222 S227 L228N221-Y224 HydrophobicContact CB-CD2 3.52Å; N221-Y224 HydrophobicContact CB-CE2 3.7Å; P222-Y224 VanDerWaalsContact C-N 3.32Å; P222-Y224 PolarHBondContact O-N 3.07Å; Y224-S227 PolarHBondContact O-N 3.25Å; Y224-L228 WeakPolarHBondContact O-CB 3.2Å; Y224-L228 PolarHBondContact O-N 2.79Å
225A70.5Confident69.9Low14 Ų1456 Ų5612%0.11632%0.318CS..Hα-helixtrans-63.4-43175.500000111.2L217 P222 L228 Y229L217-A225 HydrophobicContact CD2-CB 4.12Å; P222-A225 PolarHBondContact O-N 3.5Å; A225-L228 PolarHBondContact O-N 3.42Å; A225-Y229 HydrophobicContact CB-CE2 4.45Å; A225-Y229 WeakPolarHBondContact O-CD2 3.48Å; A225-Y229 PolarHBondContact O-N 3.33Å
226F75.3Confident72.3Confident62 Ų6253.2 Ų53.227%0.27230%0.299SS..Hα-helixtrans-56.2-54.7173.8-177.5-84.7000111.6I97 P98 I101 P222 L228 Y229 F230I97-F226 HydrophobicContact CG2-CD2 4.07Å; P98-F226 HydrophobicContact CG-CE2 4.29Å; I101-F226 HydrophobicContact CD1-CB 4.4Å; I101-F226 HydrophobicContact CD1-CD2 4.09Å; P222-F226 WeakPolarHBondContact O-CB 3.09Å; P222-F226 PolarHBondContact O-N 2.83Å; F226-L228 VanDerWaalsContact C-N 3.27Å; F226-L228 PolarHBondContact O-N 3.24Å; F226-Y229 PolarHBondContact O-N 2.65Å; F226-F230 AromaticContact CD1-CD2 4Å; F226-F230 HydrophobicContact CD1-CD2 4Å; F226-F230 HydrophobicContact CD1-CE2 4.37Å; F226-F230 HydrophobicContact CD1-CG 4.39Å; F226-F230 HydrophobicContact CD2-CD2 4Å; F226-F230 AromaticContact CD2-CE2 3.71Å; F226-F230 HydrophobicContact CD2-CE2 3.71Å; F226-F230 HydrophobicContact CE1-CD1 4.29Å; F226-F230 AromaticContact CE1-CD2 3.81Å; F226-F230 HydrophobicContact CE1-CD2 3.81Å; F226-F230 HydrophobicContact CE1-CE1 4.42Å; F226-F230 AromaticContact CE1-CE2 3.95Å; F226-F230 HydrophobicContact CE1-CE2 3.95Å; F226-F230 AromaticContact CE1-CG 4Å; F226-F230 HydrophobicContact CE1-CG 4Å; F226-F230 HydrophobicContact CE1-CZ 4.26Å; F226-F230 AromaticContact CE2-CD2 3.83Å; F226-F230 HydrophobicContact CE2-CD2 3.83Å; F226-F230 AromaticContact CE2-CE2 3.22Å; F226-F230 HydrophobicContact CE2-CE2 3.22Å; F226-F230 AromaticContact CE2-CZ 3.64Å; F226-F230 HydrophobicContact CE2-CZ 3.64Å; F226-F230 HydrophobicContact CG-CD2 4.09Å; F226-F230 HydrophobicContact CG-CE2 4.27Å; F226-F230 HydrophobicContact CZ-CD1 4.24Å; F226-F230 AromaticContact CZ-CD2 3.72Å; F226-F230 HydrophobicContact CZ-CD2 3.72Å; F226-F230 AromaticContact CZ-CE1 3.92Å; F226-F230 HydrophobicContact CZ-CE1 3.92Å; F226-F230 AromaticContact CZ-CE2 3.35Å; F226-F230 HydrophobicContact CZ-CE2 3.35Å; F226-F230 HydrophobicContact CZ-CG 4.16Å; F226-F230 AromaticContact CZ-CZ 3.46Å; F226-F230 HydrophobicContact CZ-CZ 3.46Å; F226-F230 VanDerWaalsContact CZ-CZ 3.46Å; F226-F230 WeakPolarHBondContact O-CB 3.31Å; F226-F230 WeakPolarHBondContact O-CD2 3.37Å; F226-F230 PolarHBondContact O-N 3.41Å
227S81.9Confident74.8Confident80 Ų8053.8 Ų53.856%0.55930%0.301SS*.Hα-helixtrans-62-34.2-178.6-171.60000112.7W223 Y224 G231W223-S227 VanDerWaalsContact O-CB 3.27Å; W223-S227 WeakPolarHBondContact O-CB 3.42Å; W223-S227 PolarHBondContact O-N 3.42Å; Y224-S227 PolarHBondContact O-N 3.25Å; S227-G231 PolarHBondContact O-N 2.83Å
228L83.8Confident77.1Confident55 Ų5557.1 Ų57.129%0.28832%0.318SS..Hα-helixtrans-67.5-53.3177.6-18063.2000111.6L170 Y224 A225 F226 G231 W232L170-L228 HydrophobicContact CB-CD2 4.11Å; L170-L228 HydrophobicContact CD1-CD1 3.94Å; L170-L228 HydrophobicContact CD1-CD2 3.99Å; L170-L228 HydrophobicContact CD1-CG 4.45Å; Y224-L228 WeakPolarHBondContact O-CB 3.2Å; Y224-L228 PolarHBondContact O-N 2.79Å; A225-L228 PolarHBondContact O-N 3.42Å; F226-L228 VanDerWaalsContact C-N 3.27Å; F226-L228 PolarHBondContact O-N 3.24Å; L228-G231 PolarHBondContact O-N 3.25Å; L228-W232 PolarHBondContact O-N 3.36Å; L228-W232 VanDerWaalsContact O-N 3.07Å
229Y85.2Confident79.5Confident20 Ų2057.2 Ų57.28%0.07831%0.312CS..Hα-helixtrans-65.1-42-179.9-68.8-57.7000111.9C36 S171 A225 F226 G231 W232 I233C36-Y229 HydrophobicContact CB-CD1 3.88Å; C36-Y229 HydrophobicContact CB-CE1 4.48Å; S171-Y229 PolarHBondContact OG-OH 2.92Å; A225-Y229 HydrophobicContact CB-CE2 4.45Å; A225-Y229 WeakPolarHBondContact O-CD2 3.48Å; A225-Y229 PolarHBondContact O-N 3.33Å; F226-Y229 PolarHBondContact O-N 2.65Å; Y229-G231 PolarHBondContact O-N 3.37Å; Y229-W232 PolarHBondContact O-N 3.38Å; Y229-I233 WeakPolarHBondContact O-CD1 3.23Å; Y229-I233 VanDerWaalsContact O-CG1 3.31Å; Y229-I233 WeakPolarHBondContact O-CG1 3.47Å; Y229-I233 PolarHBondContact O-N 3.37Å
230F87.9Confident81.8Confident57 Ų5753.6 Ų53.625%0.2528%0.282CS..Hα-helixtrans-62.8-40.5174.3-89.9-107.5000112.2M94 I97 F226 W232 G234M94-F230 HydrophobicContact CB-CE1 3.9Å; M94-F230 HydrophobicContact CB-CZ 4.04Å; M94-F230 HydrophobicContact CE-CD1 4.07Å; M94-F230 HydrophobicContact CG-CE1 4.31Å; M94-F230 VanDerWaalsContact O-CZ 3.24Å; M94-F230 WeakPolarHBondContact O-CZ 3.39Å; M94-F230 HydrophobicContact SD-CB 4.36Å; M94-F230 HydrophobicContact SD-CD1 3.46Å; M94-F230 WeakPolarHBondContact SD-CD1 3.09Å; M94-F230 HydrophobicContact SD-CD2 4.39Å; M94-F230 HydrophobicContact SD-CE1 3.72Å; M94-F230 HydrophobicContact SD-CG 3.83Å; M94-F230 HydrophobicContact SD-CZ 4.29Å; I97-F230 HydrophobicContact CB-CE2 3.86Å; I97-F230 HydrophobicContact CD1-CD2 3.92Å; I97-F230 HydrophobicContact CD1-CE2 3.89Å; I97-F230 HydrophobicContact CG2-CD2 4.28Å; I97-F230 HydrophobicContact CG2-CE2 3.81Å; F226-F230 AromaticContact CD1-CD2 4Å; F226-F230 HydrophobicContact CD1-CD2 4Å; F226-F230 HydrophobicContact CD1-CE2 4.37Å; F226-F230 HydrophobicContact CD1-CG 4.39Å; F226-F230 HydrophobicContact CD2-CD2 4Å; F226-F230 AromaticContact CD2-CE2 3.71Å; F226-F230 HydrophobicContact CD2-CE2 3.71Å; F226-F230 HydrophobicContact CE1-CD1 4.29Å; F226-F230 AromaticContact CE1-CD2 3.81Å; F226-F230 HydrophobicContact CE1-CD2 3.81Å; F226-F230 HydrophobicContact CE1-CE1 4.42Å; F226-F230 AromaticContact CE1-CE2 3.95Å; F226-F230 HydrophobicContact CE1-CE2 3.95Å; F226-F230 AromaticContact CE1-CG 4Å; F226-F230 HydrophobicContact CE1-CG 4Å; F226-F230 HydrophobicContact CE1-CZ 4.26Å; F226-F230 AromaticContact CE2-CD2 3.83Å; F226-F230 HydrophobicContact CE2-CD2 3.83Å; F226-F230 AromaticContact CE2-CE2 3.22Å; F226-F230 HydrophobicContact CE2-CE2 3.22Å; F226-F230 AromaticContact CE2-CZ 3.64Å; F226-F230 HydrophobicContact CE2-CZ 3.64Å; F226-F230 HydrophobicContact CG-CD2 4.09Å; F226-F230 HydrophobicContact CG-CE2 4.27Å; F226-F230 HydrophobicContact CZ-CD1 4.24Å; F226-F230 AromaticContact CZ-CD2 3.72Å; F226-F230 HydrophobicContact CZ-CD2 3.72Å; F226-F230 AromaticContact CZ-CE1 3.92Å; F226-F230 HydrophobicContact CZ-CE1 3.92Å; F226-F230 AromaticContact CZ-CE2 3.35Å; F226-F230 HydrophobicContact CZ-CE2 3.35Å; F226-F230 HydrophobicContact CZ-CG 4.16Å; F226-F230 AromaticContact CZ-CZ 3.46Å; F226-F230 HydrophobicContact CZ-CZ 3.46Å; F226-F230 VanDerWaalsContact CZ-CZ 3.46Å; F226-F230 WeakPolarHBondContact O-CB 3.31Å; F226-F230 WeakPolarHBondContact O-CD2 3.37Å; F226-F230 PolarHBondContact O-N 3.41Å; F230-W232 VanDerWaalsContact C-N 3.33Å; F230-W232 PolarHBondContact O-N 3.43Å; F230-G234 PolarHBondContact O-N 2.78Å
231G90.1Very high83.8Confident42 Ų4254.9 Ų54.943%0.43329%0.286SS..Hα-helixtrans-59.4-42.8175.200000112.6S227 L228 Y229 L235S227-G231 PolarHBondContact O-N 2.83Å; L228-G231 PolarHBondContact O-N 3.25Å; Y229-G231 PolarHBondContact O-N 3.37Å; G231-L235 WeakPolarHBondContact O-CB 3.38Å; G231-L235 PolarHBondContact O-N 3.09Å
232W91.4Very high85.5Confident39 Ų3957.3 Ų57.315%0.14830%0.298CS..Hα-helixtrans-68.5-46.4177.9-84.823.3000113.8F32 C36 W166 L170 L228 Y229 F230 G234 L235 S236F32-W232 HydrophobicContact CB-CB 4.42Å; F32-W232 WeakPolarHBondContact CB-O 3.45Å; F32-W232 HydrophobicContact CD1-CB 4.38Å; F32-W232 HydrophobicContact CD1-CD2 4.02Å; F32-W232 AromaticContact CD1-CG 3.97Å; F32-W232 HydrophobicContact CD1-CG 3.97Å; C36-W232 VanDerWaalsContact SG-CB 3.52Å; W166-W232 HydrophobicContact CB-CH2 3.69Å; W166-W232 HydrophobicContact CB-CZ2 4.32Å; L170-W232 HydrophobicContact CD1-CH2 3.83Å; L170-W232 HydrophobicContact CD1-CZ2 3.33Å; L170-W232 HydrophobicContact CG-CH2 4.47Å; L170-W232 HydrophobicContact CG-CZ2 4.34Å; L228-W232 PolarHBondContact O-N 3.36Å; L228-W232 VanDerWaalsContact O-N 3.07Å; Y229-W232 PolarHBondContact O-N 3.38Å; F230-W232 VanDerWaalsContact C-N 3.33Å; F230-W232 PolarHBondContact O-N 3.43Å; W232-G234 VanDerWaalsContact C-N 3.31Å; W232-G234 PolarHBondContact O-N 3.15Å; W232-L235 PolarHBondContact O-N 3.14Å; W232-S236 PolarHBondContact O-N 3.42Å
233I91.6Very high86.9Confident0 Ų059.6 Ų59.60%031%0.308CS..Hα-helixtrans-68.6-36.5178.3-56.4152.2000110.1C36 Y90 F93 M94 I97 Y229 L235 S236 V237C36-I233 HydrophobicContact CB-CD1 4.38Å; C36-I233 HydrophobicContact CB-CG1 4.19Å; Y90-I233 WeakPolarHBondContact O-CG2 3.49Å; F93-I233 HydrophobicContact CD1-CD1 3.43Å; F93-I233 VanDerWaalsContact CD1-CD1 3.43Å; F93-I233 HydrophobicContact CD1-CG1 3.91Å; F93-I233 HydrophobicContact CE1-CD1 3.68Å; F93-I233 HydrophobicContact CE1-CG1 4.24Å; M94-I233 HydrophobicContact CE-CB 3.73Å; M94-I233 HydrophobicContact CE-CG2 3.8Å; M94-I233 HydrophobicContact CG-CG2 3.96Å; M94-I233 HydrophobicContact SD-CB 3.61Å; M94-I233 HydrophobicContact SD-CD1 3.74Å; M94-I233 HydrophobicContact SD-CG1 4.33Å; M94-I233 HydrophobicContact SD-CG2 3.7Å; I97-I233 HydrophobicContact CD1-CD1 3.39Å; Y229-I233 WeakPolarHBondContact O-CD1 3.23Å; Y229-I233 VanDerWaalsContact O-CG1 3.31Å; Y229-I233 WeakPolarHBondContact O-CG1 3.47Å; Y229-I233 PolarHBondContact O-N 3.37Å; I233-L235 VanDerWaalsContact C-N 3.32Å; I233-L235 PolarHBondContact O-N 2.96Å; I233-S236 WeakPolarHBondContact O-CB 3.36Å; I233-S236 PolarHBondContact O-N 3.48Å; I233-S236 VanDerWaalsContact O-N 3.16Å; I233-V237 WeakPolarHBondContact O-CG2 3.5Å; I233-V237 PolarHBondContact O-N 3.28Å
234G92.4Very high87.8Confident30 Ų3051.9 Ų51.931%0.30928%0.279SS..Hα-helixtrans-58.1-43.5171.500000112F230 W232 V237 L238F230-G234 PolarHBondContact O-N 2.78Å; W232-G234 VanDerWaalsContact C-N 3.31Å; W232-G234 PolarHBondContact O-N 3.15Å; G234-V237 PolarHBondContact O-N 3.31Å; G234-L238 VanDerWaalsContact O-CB 3.3Å; G234-L238 WeakPolarHBondContact O-CB 3.24Å; G234-L238 PolarHBondContact O-N 2.95Å
235L93Very high88.4Confident64 Ų6446 Ų4634%0.33526%0.26SS..Hα-helixtrans-66.1-38.8173.5-176.555.8000112.4F32 G231 W232 I233 L238 L239F32-L235 HydrophobicContact CD1-CD2 4.23Å; F32-L235 HydrophobicContact CD2-CD2 4.09Å; F32-L235 HydrophobicContact CD2-CG 4.04Å; F32-L235 HydrophobicContact CE1-CD2 3.75Å; F32-L235 HydrophobicContact CE2-CD2 3.6Å; F32-L235 HydrophobicContact CE2-CG 3.89Å; F32-L235 HydrophobicContact CG-CD2 4.4Å; F32-L235 HydrophobicContact CZ-CD2 3.41Å; F32-L235 VanDerWaalsContact CZ-CD2 3.41Å; F32-L235 HydrophobicContact CZ-CG 4.22Å; G231-L235 WeakPolarHBondContact O-CB 3.38Å; G231-L235 PolarHBondContact O-N 3.09Å; W232-L235 PolarHBondContact O-N 3.14Å; I233-L235 VanDerWaalsContact C-N 3.32Å; I233-L235 PolarHBondContact O-N 2.96Å; L235-L238 HydrophobicContact CD1-CD2 4.44Å; L235-L238 PolarHBondContact O-N 3.45Å; L235-L239 HydrophobicContact CD1-CD1 4.23Å; L235-L239 HydrophobicContact CD1-CG 4.11Å; L235-L239 HydrophobicContact CG-CD1 4.09Å; L235-L239 HydrophobicContact CG-CG 4.45Å; L235-L239 WeakPolarHBondContact O-CB 3.47Å; L235-L239 VanDerWaalsContact O-CG 3.22Å; L235-L239 WeakPolarHBondContact O-CG 3.39Å; L235-L239 PolarHBondContact O-N 2.84Å
236S93Very high88.6Confident0 Ų054.1 Ų54.10%029%0.287CS..Hα-helixtrans-59.2-46.4173.3-1750000112.3S29 Y90 W232 I233 T240S29-S236 WeakPolarHBondContact O-CB 3.41Å; S29-S236 PolarHBondContact O-OG 2.65Å; S29-S236 PolarHBondContact OG-O 3.33Å; S29-S236 PolarHBondContact OG-OG 3.16Å; Y90-S236 VanDerWaalsContact CE2-OG 3.32Å; Y90-S236 WeakPolarHBondContact CE2-OG 3.42Å; W232-S236 PolarHBondContact O-N 3.42Å; I233-S236 WeakPolarHBondContact O-CB 3.36Å; I233-S236 PolarHBondContact O-N 3.48Å; I233-S236 VanDerWaalsContact O-N 3.16Å; S236-T240 PolarHBondContact O-N 3.4Å; S236-T240 VanDerWaalsContact O-N 3.14Å
237V93.4Very high88.2Confident28 Ų2852.5 Ų52.517%0.1728%0.281CS..Hα-helixtrans-61.4-47.4174.5166.30000110.8L87 Y90 I233 G234 L239 T240 L241L87-V237 HydrophobicContact CD2-CB 4.41Å; L87-V237 HydrophobicContact CD2-CG1 4.07Å; L87-V237 HydrophobicContact CD2-CG2 4.46Å; Y90-V237 HydrophobicContact CD2-CG2 3.99Å; Y90-V237 HydrophobicContact CG-CG2 4.26Å; I233-V237 WeakPolarHBondContact O-CG2 3.5Å; I233-V237 PolarHBondContact O-N 3.28Å; G234-V237 PolarHBondContact O-N 3.31Å; V237-L239 PolarHBondContact O-N 3.47Å; V237-T240 PolarHBondContact O-N 3.34Å; V237-L241 HydrophobicContact CG1-CD1 3.67Å; V237-L241 HydrophobicContact CG1-CG 4.3Å; V237-L241 WeakPolarHBondContact O-CB 3.38Å; V237-L241 WeakPolarHBondContact O-CG 3.5Å; V237-L241 PolarHBondContact O-N 2.95Å
238L93.6Very high87Confident87 Ų8755.7 Ų55.746%0.45529%0.288SS..Hα-helixtrans-61-45.5-179.7-172.267.5000112.2G234 L235 L241 L242G234-L238 VanDerWaalsContact O-CB 3.3Å; G234-L238 WeakPolarHBondContact O-CB 3.24Å; G234-L238 PolarHBondContact O-N 2.95Å; L235-L238 HydrophobicContact CD1-CD2 4.44Å; L235-L238 PolarHBondContact O-N 3.45Å; L238-L241 PolarHBondContact O-N 3.35Å; L238-L242 HydrophobicContact CD1-CD1 3.62Å; L238-L242 HydrophobicContact CD1-CG 4.01Å; L238-L242 HydrophobicContact CG-CD1 3.95Å; L238-L242 HydrophobicContact CG-CG 4.44Å; L238-L242 WeakPolarHBondContact O-CB 3.37Å; L238-L242 WeakPolarHBondContact O-CG 3.49Å; L238-L242 PolarHBondContact O-N 3.33Å
239L93.6Very high85.6Confident32 Ų3253.9 Ų53.917%0.16828%0.279CS..Hα-helixtrans-62.2-44.3177.4-71168.2000111.6C28 F32 L235 V237 L243C28-L239 HydrophobicContact CB-CD1 4.43Å; F32-L239 HydrophobicContact CD2-CD1 3.75Å; F32-L239 HydrophobicContact CE2-CD1 3.67Å; L235-L239 HydrophobicContact CD1-CD1 4.23Å; L235-L239 HydrophobicContact CD1-CG 4.11Å; L235-L239 HydrophobicContact CG-CD1 4.09Å; L235-L239 HydrophobicContact CG-CG 4.45Å; L235-L239 WeakPolarHBondContact O-CB 3.47Å; L235-L239 VanDerWaalsContact O-CG 3.22Å; L235-L239 WeakPolarHBondContact O-CG 3.39Å; L235-L239 PolarHBondContact O-N 2.84Å; V237-L239 PolarHBondContact O-N 3.47Å; L239-L243 HydrophobicContact CD2-CD1 3.67Å; L239-L243 WeakPolarHBondContact O-CB 3.27Å; L239-L243 PolarHBondContact O-N 2.92Å
240T91Very high83.7Confident0 Ų060.4 Ų60.40%031%0.309CS..Hα-helixtrans-67.9-38.7176-76.90000111.9S29 K83 L87 S236 V237 L244S29-T240 WeakPolarHBondContact CB-OG1 3.42Å; S29-T240 PolarHBondContact OG-OG1 3.08Å; K83-T240 WeakPolarHBondContact CE-O 3.32Å; K83-T240 HydrophobicContact CG-CG2 4.14Å; K83-T240 PolarHBondContact NZ-O 3.07Å; L87-T240 HydrophobicContact CD1-CG2 4.21Å; L87-T240 HydrophobicContact CD2-CG2 3.69Å; L87-T240 HydrophobicContact CG-CG2 3.7Å; S236-T240 PolarHBondContact O-N 3.4Å; S236-T240 VanDerWaalsContact O-N 3.14Å; V237-T240 PolarHBondContact O-N 3.34Å; T240-L244 HydrophobicContact CG2-CD2 4.08Å; T240-L244 WeakPolarHBondContact O-CB 3.23Å
241L91.6Very high81.6Confident92 Ų9265 Ų6548%0.48233%0.33SS..Hα-helixtrans-66.1-47.6177.4-80.5172.9000112.8K83 L87 V237 L238K83-L241 PolarHBondContact NZ-O 3.01Å; L87-L241 HydrophobicContact CD1-CD2 3.59Å; L87-L241 HydrophobicContact CD1-CG 4.12Å; L87-L241 HydrophobicContact CD2-CD2 4.33Å; L87-L241 HydrophobicContact CD2-CG 3.95Å; V237-L241 HydrophobicContact CG1-CD1 3.67Å; V237-L241 HydrophobicContact CG1-CG 4.3Å; V237-L241 WeakPolarHBondContact O-CB 3.38Å; V237-L241 WeakPolarHBondContact O-CG 3.5Å; V237-L241 PolarHBondContact O-N 2.95Å; L238-L241 PolarHBondContact O-N 3.35Å
242L91.8Very high79.7Confident129 Ų12965.1 Ų65.168%0.67532%0.317SS*.Hα-helixtrans-87.4-42.7-172.4-61.9-176.1000114L238L238-L242 HydrophobicContact CD1-CD1 3.62Å; L238-L242 HydrophobicContact CD1-CG 4.01Å; L238-L242 HydrophobicContact CG-CD1 3.95Å; L238-L242 HydrophobicContact CG-CG 4.44Å; L238-L242 WeakPolarHBondContact O-CB 3.37Å; L238-L242 WeakPolarHBondContact O-CG 3.49Å; L238-L242 PolarHBondContact O-N 3.33Å
243L91.8Very high77.4Confident81 Ų8165.1 Ų65.142%0.42433%0.325SS..Hα-helixtrans-103.6-23.9-164.9-58.3-179.6000114.7K21 V25 L239K21-L243 PolarHBondContact NZ-O 3.49Å; V25-L243 HydrophobicContact CB-CB 4.37Å; V25-L243 HydrophobicContact CG1-CB 3.69Å; V25-L243 HydrophobicContact CG2-CB 3.68Å; V25-L243 HydrophobicContact CG2-CD1 4.22Å; L239-L243 HydrophobicContact CD2-CD1 3.67Å; L239-L243 WeakPolarHBondContact O-CB 3.27Å; L239-L243 PolarHBondContact O-N 2.92Å
244L88.9Confident75.3Confident2 Ų271.7 Ų71.71%0.0136%0.361CS..SBendtrans-82.7118.3-177-166.371.7000111.2N22 V25 L26 K83 L86 Y129 T240N22-L244 HydrophobicContact CB-CD1 4.16Å; N22-L244 WeakPolarHBondContact O-CD1 3.46Å; V25-L244 HydrophobicContact CB-CD1 4.4Å; V25-L244 HydrophobicContact CG1-CB 3.93Å; V25-L244 HydrophobicContact CG1-CD1 4.08Å; L26-L244 HydrophobicContact CB-CD1 4.15Å; K83-L244 WeakPolarHBondContact CD-O 2.88Å; K83-L244 PolarHBondContact NZ-O 2.87Å; L86-L244 HydrophobicContact CD1-CD2 3.87Å; Y129-L244 HydrophobicContact CE1-CD1 3.97Å; Y129-L244 HydrophobicContact CE2-CD1 4.44Å; Y129-L244 HydrophobicContact CE2-CD2 4.33Å; Y129-L244 HydrophobicContact CE2-CG 4.33Å; Y129-L244 WeakPolarHBondContact OH-CD1 3.23Å; T240-L244 HydrophobicContact CG2-CD2 4.08Å; T240-L244 WeakPolarHBondContact O-CB 3.23Å
245D84.1Confident73.3Confident53 Ų5373 Ų7328%0.28336%0.358SS..  trans-71.4146.3179.1-54.8-32.2000111.3R18 K21 N22 Y129 L247R18-D245 VanDerWaalsContact CD-OD2 3.29Å; R18-D245 WeakPolarHBondContact CD-OD2 3.22Å; R18-D245 WeakPolarHBondContact CG-OD2 3.41Å; K21-D245 IonicContact NZ-OD1 2.75Å; K21-D245 PolarHBondContact NZ-OD1 3.13Å; K21-D245 IonicContact NZ-OD2 2.91Å; K21-D245 PolarHBondContact NZ-OD2 2.87Å; N22-D245 PolarHBondContact ND2-OD2 2.96Å; N22-D245 PolarHBondContact OD1-N 3.03Å; N22-D245 PolarHBondContact OD1-OD2 3.07Å; Y129-D245 PolarHBondContact OH-O 2.8Å; D245-L247 PolarHBondContact O-N 3.5Å
246R74.1Confident71.4Confident183 Ų18374.7 Ų74.769%0.69136%0.364SS*.  trans-69.2101.4172.8-71.7-171.3-177.7-159.81.7110K83 Q248K83-R246 HydrophobicContact CD-CG 4.29Å; R246-Q248 PolarHBondContact O-N 3.39Å
247L68.3Low69.5Low28 Ų2882.8 Ų82.815%0.14740%0.399CS..  trans-78.188.6176.1-165.675.7000110.6Y129 N132 D245 V249Y129-L247 HydrophobicContact CD2-CB 3.97Å; Y129-L247 HydrophobicContact CD2-CD2 4.12Å; Y129-L247 HydrophobicContact CE2-CB 3.46Å; Y129-L247 VanDerWaalsContact CE2-CB 3.46Å; Y129-L247 HydrophobicContact CE2-CD2 4.23Å; Y129-L247 HydrophobicContact CE2-CG 4.44Å; Y129-L247 HydrophobicContact CG-CD2 4.3Å; N132-L247 HydrophobicContact CB-CD2 3.97Å; D245-L247 PolarHBondContact O-N 3.5Å; L247-V249 HydrophobicContact CD2-CG2 3.91Å; L247-V249 HydrophobicContact CG-CG2 3.82Å
248Q55.7Low67.9Low148 Ų14882.6 Ų82.669%0.69240%0.4SS*.  trans-72.2125.7164.6-74175.6-39.400109.3R136 R246R136-Q248 PolarHBondContact NH2-O 2.89Å; R246-Q248 PolarHBondContact O-N 3.39Å
249V55.1Low66.6Low17 Ų1780.5 Ų80.510%0.10339%0.393CS..  trans-120.393-174.4-177.80000110.1N132 L247 F251 Y252N132-V249 HydrophobicContact CB-CG2 4.08Å; N132-V249 WeakPolarHBondContact OD1-CG1 3.28Å; L247-V249 HydrophobicContact CD2-CG2 3.91Å; L247-V249 HydrophobicContact CG-CG2 3.82Å; V249-F251 HydrophobicContact CG1-CB 4.06Å; V249-F251 HydrophobicContact CG1-CD2 4.44Å; V249-F251 PolarHBondContact O-N 2.88Å; V249-F251 VanDerWaalsContact O-N 3.13Å; V249-Y252 WeakPolarHBondContact O-CB 3.45Å; V249-Y252 PolarHBondContact O-N 3.35Å
250H44.7Very low65.4Low156 Ų15680.4 Ų80.472%0.72240%0.397SS*.G310 helixtrans-58.8-24.2178.4-69.4-69.5000114.2Y252 A253H250-Y252 PolarHBondContact O-N 3.12Å; H250-A253 WeakPolarHBondContact O-CB 3.45Å; H250-A253 PolarHBondContact O-N 2.94Å
251F45Very low64.4Low155 Ų15590 Ų9068%0.6843%0.433SS*.G310 helixtrans-61.4-21.5172.7-65.2-74.1000113.6V249 A253V249-F251 HydrophobicContact CG1-CB 4.06Å; V249-F251 HydrophobicContact CG1-CD2 4.44Å; V249-F251 PolarHBondContact O-N 2.88Å; V249-F251 VanDerWaalsContact O-N 3.13Å; F251-A253 VanDerWaalsContact C-N 3.34Å
252Y50.7Low63.6Low44 Ų4491 Ų9117%0.17344%0.435CS..G310 helixtrans-80.9-11.6174.6-128.7-94.8000113.3V249 H250 N254 K255 E256 D400V249-Y252 WeakPolarHBondContact O-CB 3.45Å; V249-Y252 PolarHBondContact O-N 3.35Å; H250-Y252 PolarHBondContact O-N 3.12Å; Y252-N254 PolarHBondContact O-N 2.89Å; Y252-N254 VanDerWaalsContact O-N 3.14Å; Y252-K255 HydrophobicContact CD1-CB 3.95Å; Y252-K255 HydrophobicContact CE1-CB 3.93Å; Y252-K255 CarbonylContact O-C 3.5Å; Y252-K255 WeakPolarHBondContact O-CA 3.46Å; Y252-K255 PolarHBondContact O-N 3.09Å; Y252-E256 PolarHBondContact O-N 3.37Å; Y252-D400 PolarHBondContact OH-OD2 3.23Å
253A42.6Very low62.5Low38 Ų3886.1 Ų86.131%0.31441%0.41SS..Hα-helixtrans-63.9-22.1-174.900000114.3H250 F251 E256H250-A253 WeakPolarHBondContact O-CB 3.45Å; H250-A253 PolarHBondContact O-N 2.94Å; F251-A253 VanDerWaalsContact C-N 3.34Å; A253-E256 WeakPolarHBondContact CA-OE2 3.42Å
254N46.7Very low61.7Low138 Ų13884.8 Ų84.874%0.73840%0.403SS*.Hα-helixtrans-78.6-32.4169.2-96.7-0.4000112.7Y252Y252-N254 PolarHBondContact O-N 2.89Å; Y252-N254 VanDerWaalsContact O-N 3.14Å
255K51.6Low61.2Low57 Ų5790.3 Ų90.325%0.24843%0.432CS..Hα-helixtrans-77.9-24.7171.9-71.9-163.5-179.6-171.60112.5Y252 K257 A258 D400Y252-K255 HydrophobicContact CD1-CB 3.95Å; Y252-K255 HydrophobicContact CE1-CB 3.93Å; Y252-K255 CarbonylContact O-C 3.5Å; Y252-K255 WeakPolarHBondContact O-CA 3.46Å; Y252-K255 PolarHBondContact O-N 3.09Å; K255-K257 PolarHBondContact O-N 3.12Å; K255-A258 WeakPolarHBondContact O-CB 3.3Å; K255-A258 PolarHBondContact O-N 3.1Å; K255-A258 VanDerWaalsContact O-N 3.16Å; K255-D400 IonicContact NZ-OD1 2.74Å; K255-D400 PolarHBondContact NZ-OD1 3.42Å; K255-D400 IonicContact NZ-OD2 2.74Å; K255-D400 PolarHBondContact NZ-OD2 2.77Å
256E52.7Low60.7Low101 Ų10190 Ų9047%0.47244%0.437SS..Hα-helixtrans-59.1-31.1172.6-78.4-176.9131.800112.8R78 Y252 A253R78-E256 PolarHBondContact NE-O 3.46Å; R78-E256 PolarHBondContact NH2-O 3.05Å; Y252-E256 PolarHBondContact O-N 3.37Å; A253-E256 WeakPolarHBondContact CA-OE2 3.42Å
257K52.2Low60.8Low170 Ų17081.8 Ų81.874%0.73941%0.407SS*.THydrogen-bonded Turntrans-73.4-29.4176.8-67.1-177.3-179.9178.70113.6K255K255-K257 PolarHBondContact O-N 3.12Å
258A61Low61.3Low23 Ų2384.8 Ų84.819%0.1943%0.426CS..SBendtrans-62.4141.6-177.800000111.8R78 K255 E262 L263R78-A258 PolarHBondContact NH1-O 3.5Å; R78-A258 PolarHBondContact NH2-O 2.83Å; K255-A258 WeakPolarHBondContact O-CB 3.3Å; K255-A258 PolarHBondContact O-N 3.1Å; K255-A258 VanDerWaalsContact O-N 3.16Å; A258-E262 WeakPolarHBondContact CA-OE2 3.3Å; A258-L263 HydrophobicContact CB-CD2 4.14Å; A258-L263 HydrophobicContact CB-CG 4.15Å
259S65.3Low62.4Low43 Ų4385.2 Ų85.230%0.30143%0.428SS..  trans-64.7150.1178.1-174.20000111.7R261 E262 L263S259-R261 PolarHBondContact O-N 2.89Å; S259-R261 PolarHBondContact OG-N 2.77Å; S259-E262 WeakPolarHBondContact CB-OE1 3.44Å; S259-E262 VanDerWaalsContact N-CD 3.34Å; S259-E262 PolarHBondContact N-OE2 3.34Å; S259-E262 WeakPolarHBondContact O-CB 3.15Å; S259-E262 PolarHBondContact O-N 3.38Å; S259-L263 PolarHBondContact O-N 3.06Å
260A67.9Low63.5Low31 Ų3185.4 Ų85.426%0.25643%0.428SS..Hα-helixtrans-52.2-37.9168.500000111.9T74 L264T74-A260 HydrophobicContact CG2-CB 3.91Å; T74-A260 WeakPolarHBondContact CG2-O 3.42Å; A260-L264 PolarHBondContact O-N 3.32Å
261R71.1Confident65.2Low200 Ų20080.6 Ų80.676%0.75541%0.407SS*.Hα-helixtrans-69.4-39.7176.6-67.8-176.2178.3178.6-0.2112S259 L264 L265S259-R261 PolarHBondContact O-N 2.89Å; S259-R261 PolarHBondContact OG-N 2.77Å; R261-L264 PolarHBondContact O-N 3.45Å; R261-L265 VanDerWaalsContact O-CB 3.28Å; R261-L265 WeakPolarHBondContact O-CB 3.33Å; R261-L265 WeakPolarHBondContact O-CD1 3.19Å; R261-L265 WeakPolarHBondContact O-CG 3.09Å; R261-L265 PolarHBondContact O-N 3.31Å
262E74Confident66.7Low113 Ų11375.9 Ų75.953%0.52840%0.402SS..Hα-helixtrans-63.3-41.3176.6-72146.2-137.300111.9A258 S259 L265 A266A258-E262 WeakPolarHBondContact CA-OE2 3.3Å; S259-E262 WeakPolarHBondContact CB-OE1 3.44Å; S259-E262 VanDerWaalsContact N-CD 3.34Å; S259-E262 PolarHBondContact N-OE2 3.34Å; S259-E262 WeakPolarHBondContact O-CB 3.15Å; S259-E262 PolarHBondContact O-N 3.38Å; E262-L265 PolarHBondContact O-N 2.87Å; E262-A266 VanDerWaalsContact O-CB 3.24Å; E262-A266 WeakPolarHBondContact O-CB 3.35Å; E262-A266 PolarHBondContact O-N 2.67Å
263L70.2Confident68.2Low28 Ų2876.8 Ų76.815%0.14741%0.41CS..Hα-helixtrans-68.4-36.6178.6-66.7172.8000112.7G73 A258 S259 N267G73-L263 VanDerWaalsContact O-CD1 3.25Å; G73-L263 WeakPolarHBondContact O-CD1 3.44Å; A258-L263 HydrophobicContact CB-CD2 4.14Å; A258-L263 HydrophobicContact CB-CG 4.15Å; S259-L263 PolarHBondContact O-N 3.06Å; L263-N267 PolarHBondContact O-N 3.47Å; L263-N267 VanDerWaalsContact O-N 3.16Å
264L74.4Confident69.8Low53 Ų5378.3 Ų78.328%0.27742%0.423SS..Hα-helixtrans-68.2-45.8170.6-83.7166.3000112.2L70 L71 T74 A260 R261 A266 N267 V268L70-L264 HydrophobicContact CB-CD2 4.43Å; L70-L264 WeakPolarHBondContact O-CD2 3.43Å; L71-L264 HydrophobicContact CD2-CD1 3.98Å; L71-L264 HydrophobicContact CD2-CD2 4.12Å; T74-L264 HydrophobicContact CG2-CD1 3.68Å; T74-L264 HydrophobicContact CG2-CD2 4.46Å; T74-L264 HydrophobicContact CG2-CG 3.54Å; A260-L264 PolarHBondContact O-N 3.32Å; R261-L264 PolarHBondContact O-N 3.45Å; L264-A266 VanDerWaalsContact C-N 3.28Å; L264-A266 PolarHBondContact O-N 3.01Å; L264-N267 PolarHBondContact O-N 3.43Å; L264-V268 WeakPolarHBondContact O-CG2 3.47Å; L264-V268 PolarHBondContact O-N 3.28Å
265L77.8Confident71.1Confident117 Ų11778.3 Ų78.361%0.61341%0.412SS*.Hα-helixtrans-62.9-35.4177.9-72.2168.5000111.4R261 E262 V268 H269R261-L265 VanDerWaalsContact O-CB 3.28Å; R261-L265 WeakPolarHBondContact O-CB 3.33Å; R261-L265 WeakPolarHBondContact O-CD1 3.19Å; R261-L265 WeakPolarHBondContact O-CG 3.09Å; R261-L265 PolarHBondContact O-N 3.31Å; E262-L265 PolarHBondContact O-N 2.87Å; L265-V268 PolarHBondContact O-N 3.37Å; L265-H269 WeakPolarHBondContact O-CB 3.21Å; L265-H269 PolarHBondContact O-N 2.84Å
266A73.4Confident72.5Confident48 Ų4875.6 Ų75.640%0.39740%0.401SS..Hα-helixtrans-63.4-46.5172.800000111.9E262 L264 H269 L270E262-A266 VanDerWaalsContact O-CB 3.24Å; E262-A266 WeakPolarHBondContact O-CB 3.35Å; E262-A266 PolarHBondContact O-N 2.67Å; L264-A266 VanDerWaalsContact C-N 3.28Å; L264-A266 PolarHBondContact O-N 3.01Å; A266-H269 PolarHBondContact O-N 2.74Å; A266-L270 WeakPolarHBondContact O-CB 3.47Å; A266-L270 PolarHBondContact O-N 3.47Å
267N76.3Confident74Confident10 Ų1077.7 Ų77.75%0.05341%0.408CS..Hα-helixtrans-62.7-44175.5-74.5-16.3000111.8L70 L263 L264 L270 I271 S401L70-N267 HydrophobicContact CD2-CB 4.47Å; L263-N267 PolarHBondContact O-N 3.47Å; L263-N267 VanDerWaalsContact O-N 3.16Å; L264-N267 PolarHBondContact O-N 3.43Å; N267-L270 PolarHBondContact O-N 2.91Å; N267-I271 WeakPolarHBondContact O-CG1 3.38Å; N267-I271 PolarHBondContact O-N 3.45Å; N267-S401 WeakPolarHBondContact OD1-CB 3.4Å; N267-S401 PolarHBondContact OD1-OG 3.21Å
268V78.7Confident75.2Confident91 Ų9172.7 Ų72.755%0.55239%0.385SS*.Hα-helixtrans-66.8-40.8177.9171.60000111.9L264 L265 I271 G272L264-V268 WeakPolarHBondContact O-CG2 3.47Å; L264-V268 PolarHBondContact O-N 3.28Å; L265-V268 PolarHBondContact O-N 3.37Å; V268-I271 WeakPolarHBondContact O-CB 3.39Å; V268-I271 PolarHBondContact O-N 3.03Å; V268-G272 PolarHBondContact O-N 3.34Å
269H80.1Confident76.3Confident156 Ų15672 Ų7272%0.72238%0.378SS*.Hα-helixtrans-66-38.5175.3-175.285.5000111.5L265 A266 G272 N273L265-H269 WeakPolarHBondContact O-CB 3.21Å; L265-H269 PolarHBondContact O-N 2.84Å; A266-H269 PolarHBondContact O-N 2.74Å; H269-G272 WeakPolarHBondContact O-CA 3.29Å; H269-G272 PolarHBondContact O-N 2.87Å; H269-N273 PolarHBondContact O-N 2.89Å
270L77.8Confident77.3Confident21 Ų2171.7 Ų71.711%0.1137%0.372CS..Hα-helixtrans-67.9-35.7176.3-173.759.3000112.2A266 N267 G272 N273 L276 F395 I405A266-L270 WeakPolarHBondContact O-CB 3.47Å; A266-L270 PolarHBondContact O-N 3.47Å; N267-L270 PolarHBondContact O-N 2.91Å; L270-G272 PolarHBondContact O-N 3.18Å; L270-N273 HydrophobicContact CD1-CB 4.34Å; L270-N273 WeakPolarHBondContact O-CB 3.34Å; L270-N273 PolarHBondContact O-N 3.33Å; L270-L276 HydrophobicContact CD1-CD2 4.35Å; L270-L276 HydrophobicContact CD2-CD2 4.4Å; L270-L276 HydrophobicContact CG-CD2 3.77Å; L270-F395 HydrophobicContact CD1-CD1 4.17Å; L270-F395 HydrophobicContact CD1-CE1 3.8Å; L270-F395 HydrophobicContact CD1-CZ 4.08Å; L270-I405 HydrophobicContact CB-CD1 3.91Å; L270-I405 HydrophobicContact CD2-CD1 3.78Å; L270-I405 HydrophobicContact CG-CD1 3.78Å
271I79.7Confident78.2Confident56 Ų5671.9 Ų71.929%0.28737%0.371SS..Hα-helixtrans-58.6-35.5167.4-71.3167.5000111.2L70 N267 V268 N273 I280 I405L70-I271 HydrophobicContact CD2-CD1 4.44Å; N267-I271 WeakPolarHBondContact O-CG1 3.38Å; N267-I271 PolarHBondContact O-N 3.45Å; V268-I271 WeakPolarHBondContact O-CB 3.39Å; V268-I271 PolarHBondContact O-N 3.03Å; I271-N273 VanDerWaalsContact C-N 3.27Å; I271-N273 PolarHBondContact O-N 3.34Å; I271-I280 HydrophobicContact CG2-CD1 3.96Å; I271-I405 HydrophobicContact CD1-CG1 4.31Å; I271-I405 HydrophobicContact CG1-CD1 3.76Å; I271-I405 HydrophobicContact CG1-CG1 3.88Å; I271-I405 HydrophobicContact CG1-CG2 3.98Å
272G77.3Confident79Confident56 Ų5663.1 Ų63.158%0.57734%0.339SS*.THydrogen-bonded Turntrans-68.8-16.3174.600000115.2V268 H269 L270 A274V268-G272 PolarHBondContact O-N 3.34Å; H269-G272 WeakPolarHBondContact O-CA 3.29Å; H269-G272 PolarHBondContact O-N 2.87Å; L270-G272 PolarHBondContact O-N 3.18Å; G272-A274 PolarHBondContact O-N 2.92Å
273N80.7Confident79.8Confident62 Ų6257.7 Ų57.733%0.33231%0.314SS..SBendtrans-65.6125.9-176.6-173.4-43.1000111.5H269 L270 I271 R275 L276 K277H269-N273 PolarHBondContact O-N 2.89Å; L270-N273 HydrophobicContact CD1-CB 4.34Å; L270-N273 WeakPolarHBondContact O-CB 3.34Å; L270-N273 PolarHBondContact O-N 3.33Å; I271-N273 VanDerWaalsContact C-N 3.27Å; I271-N273 PolarHBondContact O-N 3.34Å; N273-R275 PolarHBondContact O-N 2.89Å; N273-R275 WeakPolarHBondContact OD1-CB 3.47Å; N273-R275 PolarHBondContact OD1-N 3.39Å; N273-L276 HydrophobicContact CB-CB 4.49Å; N273-L276 PolarHBondContact O-N 3.26Å; N273-K277 WeakPolarHBondContact O-CB 3.35Å; N273-K277 PolarHBondContact O-N 3.44Å
274A76.3Confident80.9Confident71 Ų7158.4 Ų58.459%0.58732%0.317SS*.THydrogen-bonded Turntrans-62.4-11.8-177.500000115.4G272 R278G272-A274 PolarHBondContact O-N 2.92Å; A274-R278 PolarHBondContact O-NE 2.93Å; A274-R278 PolarHBondContact O-NH2 3.13Å
275R75.1Confident81.7Confident137 Ų13756.3 Ų56.352%0.51731%0.307SS..THydrogen-bonded Turntrans-79.7-50.2165.8-70-177.3174.2168.30.3111.5N273 F395N273-R275 PolarHBondContact O-N 2.89Å; N273-R275 WeakPolarHBondContact OD1-CB 3.47Å; N273-R275 PolarHBondContact OD1-N 3.39Å; R275-F395 HydrophobicContact CB-CZ 4.05Å
276L81.6Confident82.4Confident0 Ų051 Ų510%028%0.279CS..G310 helixtrans-74-35.6-176.6-167.856.8000112.8L270 N273 R278 L279 I280 F283 F395 I405L270-L276 HydrophobicContact CD1-CD2 4.35Å; L270-L276 HydrophobicContact CD2-CD2 4.4Å; L270-L276 HydrophobicContact CG-CD2 3.77Å; N273-L276 HydrophobicContact CB-CB 4.49Å; N273-L276 PolarHBondContact O-N 3.26Å; L276-R278 PolarHBondContact O-N 2.88Å; L276-R278 VanDerWaalsContact O-N 3.13Å; L276-L279 HydrophobicContact CD1-CB 4.29Å; L276-L279 HydrophobicContact CD1-CD1 4.11Å; L276-L279 WeakPolarHBondContact O-CA 3.27Å; L276-L279 WeakPolarHBondContact O-CB 3.37Å; L276-L279 PolarHBondContact O-N 2.86Å; L276-I280 PolarHBondContact O-N 3.13Å; L276-I280 VanDerWaalsContact O-N 3.13Å; L276-F283 HydrophobicContact CD1-CE2 3.96Å; L276-F283 HydrophobicContact CD1-CZ 4.39Å; L276-F395 HydrophobicContact CB-CE2 3.92Å; L276-F395 HydrophobicContact CB-CZ 4.07Å; L276-F395 HydrophobicContact CD1-CE2 4.17Å; L276-F395 HydrophobicContact CG-CE2 4.44Å; L276-I405 HydrophobicContact CD2-CB 4.09Å; L276-I405 HydrophobicContact CD2-CD1 3.53Å; L276-I405 HydrophobicContact CD2-CG1 4.4Å; L276-I405 HydrophobicContact CD2-CG2 3.76Å; L276-I405 HydrophobicContact CG-CG2 4.22Å
277K82.6Confident83.4Confident146 Ų14648.7 Ų48.764%0.63526%0.26SS*.G310 helixtrans-56-29.8176-173.4173.7179.3178.40113.4N273N273-K277 WeakPolarHBondContact O-CB 3.35Å; N273-K277 PolarHBondContact O-N 3.44Å
278R78.8Confident84.2Confident65 Ų6549 Ų4925%0.24526%0.261CS..G310 helixtrans-78.2-19.4174.1-73.1-179.5-79.1142.9-5.7114.1A274 L276 G444 V445A274-R278 PolarHBondContact O-NE 2.93Å; A274-R278 PolarHBondContact O-NH2 3.13Å; L276-R278 PolarHBondContact O-N 2.88Å; L276-R278 VanDerWaalsContact O-N 3.13Å; R278-G444 PolarHBondContact NH1-O 3.38Å; R278-V445 HydrophobicContact CB-CG2 3.67Å
279L83.5Confident84.9Confident8 Ų844.9 Ų44.94%0.04224%0.236CC..THydrogen-bonded Turntrans-91.5-25.3179.1-69.3165.6000112.8L276 L282 F283 M390 V445L276-L279 HydrophobicContact CD1-CB 4.29Å; L276-L279 HydrophobicContact CD1-CD1 4.11Å; L276-L279 WeakPolarHBondContact O-CA 3.27Å; L276-L279 WeakPolarHBondContact O-CB 3.37Å; L276-L279 PolarHBondContact O-N 2.86Å; L279-L282 WeakPolarHBondContact O-CB 3.11Å; L279-L282 PolarHBondContact O-N 3.15Å; L279-L282 VanDerWaalsContact O-N 3.11Å; L279-F283 HydrophobicContact CB-CE1 4.04Å; L279-F283 HydrophobicContact CB-CE2 3.91Å; L279-F283 HydrophobicContact CB-CZ 3.5Å; L279-F283 VanDerWaalsContact CB-CZ 3.5Å; L279-F283 HydrophobicContact CD1-CZ 4.34Å; L279-F283 HydrophobicContact CG-CZ 4.36Å; L279-F283 WeakPolarHBondContact O-CD1 3.45Å; L279-F283 WeakPolarHBondContact O-CG 3.32Å; L279-F283 PolarHBondContact O-N 3.18Å; L279-M390 HydrophobicContact CD2-CE 3.78Å; L279-V445 HydrophobicContact CD2-CB 4.44Å; L279-V445 HydrophobicContact CD2-CG1 3.68Å; L279-V445 HydrophobicContact CD2-CG2 3.94Å; L279-V445 HydrophobicContact CG-CG2 4.23Å
280I87.1Confident85.5Confident37 Ų3737.5 Ų37.519%0.1920%0.202CC..Hα-helixtrans-55.2-42.6-179-70.5170.4000113.4I271 L276 L282 F283 I284 I405I271-I280 HydrophobicContact CG2-CD1 3.96Å; L276-I280 PolarHBondContact O-N 3.13Å; L276-I280 VanDerWaalsContact O-N 3.13Å; I280-L282 VanDerWaalsContact C-N 3.33Å; I280-L282 PolarHBondContact O-N 2.89Å; I280-F283 PolarHBondContact O-N 3.31Å; I280-F283 VanDerWaalsContact O-N 3.13Å; I280-I284 HydrophobicContact CG2-CD1 3.83Å; I280-I284 HydrophobicContact CG2-CG1 4.43Å; I280-I284 WeakPolarHBondContact O-CG1 3.45Å; I280-I284 PolarHBondContact O-N 2.98Å; I280-I405 HydrophobicContact CD1-CG2 4.41Å; I280-I405 HydrophobicContact CG1-CG2 4.38Å
281P87Confident86.3Confident35 Ų3536.5 Ų36.523%0.22720%0.197CC..Hα-helixtrans-58.1-40.9175.2-25.935.6000113.4F283 I284 C285P281-F283 VanDerWaalsContact C-N 3.32Å; P281-F283 PolarHBondContact O-N 2.79Å; P281-I284 PolarHBondContact O-N 3.39Å; P281-C285 WeakPolarHBondContact O-CB 3.44Å; P281-C285 PolarHBondContact O-N 2.87Å
282L87.1Confident87Confident15 Ų1534 Ų348%0.07918%0.184CC..Hα-helixtrans-63.1-36.9176175.465.8000111.9L279 I280 C285 I286 W383 M390 A440L279-L282 WeakPolarHBondContact O-CB 3.11Å; L279-L282 PolarHBondContact O-N 3.15Å; L279-L282 VanDerWaalsContact O-N 3.11Å; I280-L282 VanDerWaalsContact C-N 3.33Å; I280-L282 PolarHBondContact O-N 2.89Å; L282-C285 WeakPolarHBondContact O-CB 3.22Å; L282-C285 PolarHBondContact O-N 2.86Å; L282-I286 HydrophobicContact CD1-CD1 4.43Å; L282-I286 HydrophobicContact CG-CD1 4.23Å; L282-I286 WeakPolarHBondContact O-CD1 3.25Å; L282-I286 VanDerWaalsContact O-CG1 3.29Å; L282-I286 WeakPolarHBondContact O-CG1 3.36Å; L282-I286 PolarHBondContact O-N 2.79Å; L282-W383 HydrophobicContact CD1-CE3 3.83Å; L282-W383 HydrophobicContact CD1-CZ3 3.91Å; L282-M390 HydrophobicContact CD2-CE 4.16Å; L282-A440 HydrophobicContact CB-CB 4.46Å; L282-A440 HydrophobicContact CD1-CB 3.99Å
283F90.7Very high87.8Confident0 Ų031.4 Ų31.40%016%0.157CC..Hα-helixtrans-70.5-40.2177.5-52.3-22.9000111.8L276 L279 I280 P281 C285 I286 G287 V391 Y406 C410L276-F283 HydrophobicContact CD1-CE2 3.96Å; L276-F283 HydrophobicContact CD1-CZ 4.39Å; L279-F283 HydrophobicContact CB-CE1 4.04Å; L279-F283 HydrophobicContact CB-CE2 3.91Å; L279-F283 HydrophobicContact CB-CZ 3.5Å; L279-F283 VanDerWaalsContact CB-CZ 3.5Å; L279-F283 HydrophobicContact CD1-CZ 4.34Å; L279-F283 HydrophobicContact CG-CZ 4.36Å; L279-F283 WeakPolarHBondContact O-CD1 3.45Å; L279-F283 WeakPolarHBondContact O-CG 3.32Å; L279-F283 PolarHBondContact O-N 3.18Å; I280-F283 PolarHBondContact O-N 3.31Å; I280-F283 VanDerWaalsContact O-N 3.13Å; P281-F283 VanDerWaalsContact C-N 3.32Å; P281-F283 PolarHBondContact O-N 2.79Å; F283-C285 VanDerWaalsContact C-N 3.34Å; F283-I286 PolarHBondContact O-N 2.83Å; F283-G287 PolarHBondContact O-N 2.94Å; F283-G287 VanDerWaalsContact O-N 3.12Å; F283-V391 HydrophobicContact CE1-CG2 3.87Å; F283-V391 HydrophobicContact CE2-CG2 4.08Å; F283-V391 HydrophobicContact CZ-CG2 3.3Å; F283-Y406 AromaticContact CD1-CD2 3.52Å; F283-Y406 HydrophobicContact CD1-CD2 3.52Å; F283-Y406 AromaticContact CD1-CE2 3.8Å; F283-Y406 HydrophobicContact CD1-CE2 3.8Å; F283-Y406 HydrophobicContact CD2-CD2 4.2Å; F283-Y406 AromaticContact CE1-CD2 3.61Å; F283-Y406 HydrophobicContact CE1-CD2 3.61Å; F283-Y406 HydrophobicContact CE1-CE2 4.08Å; F283-Y406 HydrophobicContact CE2-CD2 4.26Å; F283-Y406 AromaticContact CG-CD2 3.85Å; F283-Y406 HydrophobicContact CG-CD2 3.85Å; F283-Y406 HydrophobicContact CG-CE2 4.38Å; F283-Y406 AromaticContact CZ-CD2 3.98Å; F283-Y406 HydrophobicContact CZ-CD2 3.98Å; F283-C410 WeakPolarHBondContact O-CA 3.49Å
284I92.3Very high88.3Confident43 Ų4328.5 Ų28.522%0.22114%0.141CC..Hα-helixtrans-63-43.1173.5-66.4169.5000110I280 P281 I286 G287 I288 G409 G413 I416I280-I284 HydrophobicContact CG2-CD1 3.83Å; I280-I284 HydrophobicContact CG2-CG1 4.43Å; I280-I284 WeakPolarHBondContact O-CG1 3.45Å; I280-I284 PolarHBondContact O-N 2.98Å; P281-I284 PolarHBondContact O-N 3.39Å; I284-I286 PolarHBondContact O-N 2.76Å; I284-G287 PolarHBondContact O-N 3.28Å; I284-G287 VanDerWaalsContact O-N 3.12Å; I284-I288 HydrophobicContact CG2-CD1 3.86Å; I284-I288 HydrophobicContact CG2-CG1 4.42Å; I284-I288 WeakPolarHBondContact O-CG1 3.35Å; I284-I288 PolarHBondContact O-N 3.04Å; I284-G409 WeakPolarHBondContact CA-O 3.11Å; I284-G413 WeakPolarHBondContact O-CA 3.32Å; I284-I416 HydrophobicContact CG2-CD1 4.2Å
285C91.4Very high89Confident9 Ų925.1 Ų25.16%0.06111%0.114CC..Hα-helixtrans-54.7-49.1172.4-174.90000111.8P281 L282 F283 G287 I288 N289 V436 A440P281-C285 WeakPolarHBondContact O-CB 3.44Å; P281-C285 PolarHBondContact O-N 2.87Å; L282-C285 WeakPolarHBondContact O-CB 3.22Å; L282-C285 PolarHBondContact O-N 2.86Å; F283-C285 VanDerWaalsContact C-N 3.34Å; C285-G287 PolarHBondContact O-N 3.48Å; C285-I288 PolarHBondContact O-N 3.18Å; C285-N289 WeakPolarHBondContact O-CB 3.11Å; C285-N289 PolarHBondContact O-N 2.96Å; C285-V436 HydrophobicContact CB-CG1 3.65Å; C285-A440 HydrophobicContact CB-CB 4.39Å
286I93Very high89.7Confident4 Ų419 Ų192%0.0219%0.091CC..Hα-helixtrans-58.6-35.4177.6-72.3162.3000112L282 F283 I284 E290 W383 Y406L282-I286 HydrophobicContact CD1-CD1 4.43Å; L282-I286 HydrophobicContact CG-CD1 4.23Å; L282-I286 WeakPolarHBondContact O-CD1 3.25Å; L282-I286 VanDerWaalsContact O-CG1 3.29Å; L282-I286 WeakPolarHBondContact O-CG1 3.36Å; L282-I286 PolarHBondContact O-N 2.79Å; F283-I286 PolarHBondContact O-N 2.83Å; I284-I286 PolarHBondContact O-N 2.76Å; I286-E290 PolarHBondContact O-N 2.87Å; I286-W383 HydrophobicContact CD1-CB 4.39Å; I286-W383 VanDerWaalsContact CD1-O 3.31Å; I286-W383 WeakPolarHBondContact CD1-O 3.49Å; I286-W383 HydrophobicContact CG1-CB 4.01Å; I286-Y406 HydrophobicContact CD1-CE2 4.49Å
287G94.1Very high90.2Very high0 Ų019.1 Ų19.10%09%0.092CC..Hα-helixtrans-69.1-52.3175.300000113.4F283 I284 C285 N289 E290 V291 C410F283-G287 PolarHBondContact O-N 2.94Å; F283-G287 VanDerWaalsContact O-N 3.12Å; I284-G287 PolarHBondContact O-N 3.28Å; I284-G287 VanDerWaalsContact O-N 3.12Å; C285-G287 PolarHBondContact O-N 3.48Å; G287-N289 VanDerWaalsContact C-N 3.29Å; G287-N289 PolarHBondContact O-N 3.07Å; G287-E290 PolarHBondContact O-N 3.42Å; G287-V291 PolarHBondContact O-N 3.07Å; G287-C410 VanDerWaalsContact CA-O 3.27Å; G287-C410 WeakPolarHBondContact CA-O 3.22Å
288I94Very high90.7Very high17 Ų1712.2 Ų12.29%0.0876%0.062CC..Hα-helixtrans-59.4-43.1177.9-63.7169.7000110I284 C285 E290 V291 F292 G413 I416 V433I284-I288 HydrophobicContact CG2-CD1 3.86Å; I284-I288 HydrophobicContact CG2-CG1 4.42Å; I284-I288 WeakPolarHBondContact O-CG1 3.35Å; I284-I288 PolarHBondContact O-N 3.04Å; C285-I288 PolarHBondContact O-N 3.18Å; I288-E290 PolarHBondContact O-N 3.38Å; I288-V291 PolarHBondContact O-N 3.38Å; I288-V291 VanDerWaalsContact O-N 3.16Å; I288-F292 WeakPolarHBondContact O-CB 3.07Å; I288-F292 PolarHBondContact O-N 3.17Å; I288-G413 WeakPolarHBondContact CG1-O 3.38Å; I288-G413 PolarHBondContact N-O 2.99Å; I288-I416 HydrophobicContact CD1-CG2 4.06Å; I288-I416 HydrophobicContact CG1-CB 4.44Å; I288-I416 HydrophobicContact CG1-CG2 4.33Å; I288-V433 HydrophobicContact CG2-CG2 4.09Å
289N92.8Very high91.1Very high4 Ų49.2 Ų9.22%0.0215%0.05CC..Hα-helixtrans-69.4-16-178.3-157.867.3000113.9C285 G287 Q349 W376 V433C285-N289 WeakPolarHBondContact O-CB 3.11Å; C285-N289 PolarHBondContact O-N 2.96Å; G287-N289 VanDerWaalsContact C-N 3.29Å; G287-N289 PolarHBondContact O-N 3.07Å; N289-Q349 PolarHBondContact ND2-NE2 3.34Å; N289-Q349 PolarHBondContact OD1-NE2 2.89Å; N289-W376 PolarHBondContact ND2-NE1 3.23Å; N289-W376 PolarHBondContact O-NE1 3.25Å; N289-W376 WeakPolarHBondContact OD1-CZ2 3.46Å; N289-V433 WeakPolarHBondContact OD1-CG1 3.01Å
290E93.1Very high91.3Very high2 Ų28.8 Ų8.81%0.0095%0.048CC..Hα-helixtrans-80.6-46167.7-164.2-179.1126.700111.3R41 I286 G287 I288 V293 V294 H380 R384 M414R41-E290 IonicContact CZ-OE1 3.96Å; R41-E290 VanDerWaalsContact CZ-OE1 3.24Å; R41-E290 IonicContact NH1-OE1 2.77Å; R41-E290 PolarHBondContact NH1-OE1 2.86Å; R41-E290 IonicContact NH2-OE1 3.96Å; R41-E290 PolarHBondContact NH2-OE1 3Å; I286-E290 PolarHBondContact O-N 2.87Å; G287-E290 PolarHBondContact O-N 3.42Å; I288-E290 PolarHBondContact O-N 3.38Å; E290-V293 VanDerWaalsContact O-CG1 3.29Å; E290-V293 WeakPolarHBondContact O-CG1 3.35Å; E290-V294 HydrophobicContact CG-CG2 4.46Å; E290-V294 WeakPolarHBondContact O-CB 3.34Å; E290-V294 VanDerWaalsContact O-CG2 3.27Å; E290-V294 WeakPolarHBondContact O-CG2 3.23Å; E290-V294 PolarHBondContact O-N 3.31Å; E290-V294 VanDerWaalsContact O-N 3.11Å; E290-H380 IonicContact OE2-CE1 3.74Å; E290-H380 IonicContact OE2-NE2 4Å; E290-R384 IonicContact OE2-CZ 3.75Å; E290-R384 IonicContact OE2-NH1 3.92Å; E290-R384 PolarHBondContact OE2-NH1 3.05Å; E290-R384 IonicContact OE2-NH2 2.65Å; E290-R384 PolarHBondContact OE2-NH2 3.33Å; E290-M414 HydrophobicContact CB-CE 4.28Å; E290-M414 HydrophobicContact CG-CE 4.5Å; E290-M414 WeakPolarHBondContact OE2-CE 3.45Å
291V94.2Very high91.5Very high0 Ų07.1 Ų7.10%04%0.04CC..Hα-helixtrans-68.9-39.2-177.2176.70000111.8G287 I288 V293 V294 A295 M414 F418G287-V291 PolarHBondContact O-N 3.07Å; I288-V291 PolarHBondContact O-N 3.38Å; I288-V291 VanDerWaalsContact O-N 3.16Å; V291-V293 VanDerWaalsContact C-N 3.35Å; V291-V293 PolarHBondContact O-N 3.22Å; V291-V294 PolarHBondContact O-N 3.03Å; V291-A295 HydrophobicContact CG1-CB 4.31Å; V291-A295 WeakPolarHBondContact O-CB 3.17Å; V291-A295 PolarHBondContact O-N 3.31Å; V291-M414 HydrophobicContact CG2-CB 3.73Å; V291-M414 HydrophobicContact CG2-CG 3.86Å; V291-F418 HydrophobicContact CB-CD2 4.5Å; V291-F418 HydrophobicContact CB-CE2 4.21Å; V291-F418 HydrophobicContact CB-CZ 4.29Å; V291-F418 HydrophobicContact CG1-CD1 3.67Å; V291-F418 HydrophobicContact CG1-CD2 3.89Å; V291-F418 HydrophobicContact CG1-CE1 3.59Å; V291-F418 HydrophobicContact CG1-CE2 3.81Å; V291-F418 HydrophobicContact CG1-CG 3.8Å; V291-F418 HydrophobicContact CG1-CZ 3.67Å; V291-F418 HydrophobicContact CG2-CD2 3.76Å; V291-F418 HydrophobicContact CG2-CE2 3.32Å; V291-F418 HydrophobicContact CG2-CZ 3.78Å
292F94.1Very high91.7Very high4 Ų45.5 Ų5.52%0.0183%0.029CC..Iπ-helixtrans-59.5-42.7179.3-176.6-101.5000112.3I288 D296 V297 L353 M356 W376 K429 I430 V433I288-F292 WeakPolarHBondContact O-CB 3.07Å; I288-F292 PolarHBondContact O-N 3.17Å; F292-D296 HydrophobicContact CD2-CB 3.61Å; F292-D296 HydrophobicContact CE2-CB 3.74Å; F292-D296 HydrophobicContact CG-CB 4.39Å; F292-D296 PolarHBondContact O-N 3.37Å; F292-V297 HydrophobicContact CD1-CG2 3.77Å; F292-V297 HydrophobicContact CE1-CG2 3.45Å; F292-V297 VanDerWaalsContact CE1-CG2 3.45Å; F292-V297 HydrophobicContact CZ-CG2 3.97Å; F292-V297 WeakPolarHBondContact O-CG2 3.41Å; F292-V297 PolarHBondContact O-N 2.99Å; F292-L353 HydrophobicContact CE1-CD2 4.43Å; F292-M356 HydrophobicContact CE1-CE 3.93Å; F292-W376 AromaticContact CD1-CH2 3.46Å; F292-W376 HydrophobicContact CD1-CH2 3.46Å; F292-W376 VanDerWaalsContact CD1-CH2 3.46Å; F292-W376 AromaticContact CD1-CZ2 3.78Å; F292-W376 HydrophobicContact CD1-CZ2 3.78Å; F292-W376 HydrophobicContact CD1-CZ3 4.44Å; F292-W376 AromaticContact CE1-CH2 3.84Å; F292-W376 HydrophobicContact CE1-CH2 3.84Å; F292-W376 HydrophobicContact CE1-CZ3 4.49Å; F292-K429 HydrophobicContact CD2-CB 4.1Å; F292-K429 HydrophobicContact CE2-CB 3.59Å; F292-I430 HydrophobicContact CZ-CG1 3.73Å; F292-V433 HydrophobicContact CB-CG2 4.14Å; F292-V433 HydrophobicContact CD1-CG2 4.21Å; F292-V433 HydrophobicContact CD2-CG2 4.12Å; F292-V433 HydrophobicContact CG-CG2 3.87Å
293V93.8Very high91.6Very high1 Ų14.8 Ų4.81%0.0063%0.025CC..Iπ-helixtrans-73.3-37.1175.366.10000112.6E290 V291 M298 Y318 W376E290-V293 VanDerWaalsContact O-CG1 3.29Å; E290-V293 WeakPolarHBondContact O-CG1 3.35Å; V291-V293 VanDerWaalsContact C-N 3.35Å; V291-V293 PolarHBondContact O-N 3.22Å; V293-M298 HydrophobicContact CG2-CE 4.14Å; V293-M298 VanDerWaalsContact O-CE 3.25Å; V293-M298 WeakPolarHBondContact O-CE 3.49Å; V293-M298 WeakPolarHBondContact O-CG 3.45Å; V293-Y318 HydrophobicContact CG1-CE2 4.34Å; V293-W376 HydrophobicContact CB-CD2 4.07Å; V293-W376 HydrophobicContact CB-CG 4.03Å; V293-W376 HydrophobicContact CB-CZ2 4.19Å; V293-W376 HydrophobicContact CG1-CG 4.34Å; V293-W376 VanDerWaalsContact CG1-NE1 3.32Å; V293-W376 HydrophobicContact CG2-CB 4.32Å; V293-W376 HydrophobicContact CG2-CD2 4.23Å; V293-W376 HydrophobicContact CG2-CG 3.89Å
294V92Very high91.4Very high1 Ų14.8 Ų4.81%0.0063%0.025CC..Iπ-helixtrans-73.6-35.3-176164.10000112.6T42 E290 V291 M298T42-V294 HydrophobicContact CG2-CG1 3.9Å; T42-V294 VanDerWaalsContact CG2-O 3.25Å; T42-V294 WeakPolarHBondContact CG2-O 3.2Å; T42-V294 VanDerWaalsContact OG1-CG1 3.3Å; T42-V294 WeakPolarHBondContact OG1-CG1 3.32Å; E290-V294 HydrophobicContact CG-CG2 4.46Å; E290-V294 WeakPolarHBondContact O-CB 3.34Å; E290-V294 VanDerWaalsContact O-CG2 3.27Å; E290-V294 WeakPolarHBondContact O-CG2 3.23Å; E290-V294 PolarHBondContact O-N 3.31Å; E290-V294 VanDerWaalsContact O-N 3.11Å; V291-V294 PolarHBondContact O-N 3.03Å; V294-M298 VanDerWaalsContact O-CG 3.28Å; V294-M298 WeakPolarHBondContact O-CG 3.34Å
295A90.6Very high91.1Very high0 Ų03.3 Ų3.30%02%0.018CC..Iπ-helixtrans-111.9-66.9-175.100000112S45 V291 M298 Q299 F418 K421S45-A295 WeakPolarHBondContact OG-CB 3.47Å; V291-A295 HydrophobicContact CG1-CB 4.31Å; V291-A295 WeakPolarHBondContact O-CB 3.17Å; V291-A295 PolarHBondContact O-N 3.31Å; A295-M298 PolarHBondContact O-N 3.36Å; A295-Q299 WeakPolarHBondContact O-CB 3.3Å; A295-Q299 PolarHBondContact O-N 3.07Å; A295-F418 HydrophobicContact CB-CE1 4.1Å; A295-K421 HydrophobicContact CB-CD 3.99Å
296D90.9Very high90.8Very high7 Ų72.9 Ų2.94%0.0372%0.016CC..Iπ-helixtrans-64.2-46.6-171.1-62.1-82.7000113.3F292 Q299 A300 K429F292-D296 HydrophobicContact CD2-CB 3.61Å; F292-D296 HydrophobicContact CE2-CB 3.74Å; F292-D296 HydrophobicContact CG-CB 4.39Å; F292-D296 PolarHBondContact O-N 3.37Å; D296-Q299 PolarHBondContact O-N 2.89Å; D296-A300 WeakPolarHBondContact O-CB 3.37Å; D296-A300 PolarHBondContact O-N 3.41Å; D296-K429 HydrophobicContact CB-CD 4.44Å; D296-K429 WeakPolarHBondContact OD1-CD 3.41Å; D296-K429 WeakPolarHBondContact OD1-CE 3.3Å; D296-K429 IonicContact OD1-NZ 3.93Å; D296-K429 PolarHBondContact OD1-NZ 3.43Å
297V92.2Very high90.3Very high4 Ų43.5 Ų3.52%0.0242%0.02CC..Iπ-helixtrans-67-43.5178.7175.80000111F292 Q299 Y301 M356F292-V297 HydrophobicContact CD1-CG2 3.77Å; F292-V297 HydrophobicContact CE1-CG2 3.45Å; F292-V297 VanDerWaalsContact CE1-CG2 3.45Å; F292-V297 HydrophobicContact CZ-CG2 3.97Å; F292-V297 WeakPolarHBondContact O-CG2 3.41Å; F292-V297 PolarHBondContact O-N 2.99Å; V297-Q299 VanDerWaalsContact C-N 3.3Å; V297-Q299 PolarHBondContact O-N 2.83Å; V297-Y301 HydrophobicContact CG1-CD2 4.22Å; V297-Y301 WeakPolarHBondContact O-CB 3.15Å; V297-Y301 PolarHBondContact O-N 3.48Å; V297-M356 HydrophobicContact CG1-SD 3.91Å; V297-M356 HydrophobicContact CG2-CE 4.13Å; V297-M356 HydrophobicContact CG2-SD 3.76Å
298M91.7Very high89.8Confident0 Ų04.2 Ų4.20%02%0.023CC..Iπ-helixtrans-60.9-40.3175.8-64.3-57.2139.800111.4L46 V293 V294 A295 V302 A303 V311 V314 L315 V373L46-M298 HydrophobicContact CD1-CB 3.89Å; L46-M298 HydrophobicContact CD2-CB 3.87Å; L46-M298 HydrophobicContact CG-CB 4.46Å; V293-M298 HydrophobicContact CG2-CE 4.14Å; V293-M298 VanDerWaalsContact O-CE 3.25Å; V293-M298 WeakPolarHBondContact O-CE 3.49Å; V293-M298 WeakPolarHBondContact O-CG 3.45Å; V294-M298 VanDerWaalsContact O-CG 3.28Å; V294-M298 WeakPolarHBondContact O-CG 3.34Å; A295-M298 PolarHBondContact O-N 3.36Å; M298-V302 WeakPolarHBondContact O-CB 3.43Å; M298-V302 PolarHBondContact O-N 2.89Å; M298-V302 HydrophobicContact SD-CG2 4.05Å; M298-A303 WeakPolarHBondContact O-CB 3.37Å; M298-A303 PolarHBondContact O-N 3.38Å; M298-V311 HydrophobicContact CB-CG1 4.07Å; M298-V311 HydrophobicContact CG-CG1 4.11Å; M298-V311 HydrophobicContact SD-CG1 4.07Å; M298-V314 HydrophobicContact CE-CG1 4.03Å; M298-V314 HydrophobicContact SD-CG1 4.05Å; M298-L315 HydrophobicContact CE-CD2 3.62Å; M298-L315 HydrophobicContact CE-CG 4.11Å; M298-L315 HydrophobicContact CG-CD1 4.23Å; M298-L315 HydrophobicContact CG-CD2 4.3Å; M298-L315 HydrophobicContact CG-CG 4.43Å; M298-L315 HydrophobicContact SD-CD1 4.24Å; M298-L315 HydrophobicContact SD-CD2 4.04Å; M298-L315 HydrophobicContact SD-CG 3.92Å; M298-V373 HydrophobicContact CE-CG1 4.16Å; M298-V373 HydrophobicContact CE-CG2 3.61Å
299Q86.9Confident89.4Confident2 Ų23.6 Ų3.61%0.0092%0.02CC..Iπ-helixtrans-70.8-53.7179.9-151178.820.100111.6L46 T190 Y201 E203 A295 D296 V297 C304L46-Q299 HydrophobicContact CD2-CB 3.49Å; L46-Q299 VanDerWaalsContact CD2-CB 3.49Å; L46-Q299 HydrophobicContact CD2-CG 3.85Å; T190-Q299 HydrophobicContact CG2-CG 4.08Å; Y201-Q299 HydrophobicContact CE1-CB 4.39Å; Y201-Q299 HydrophobicContact CE1-CG 4Å; Y201-Q299 PolarHBondContact OH-NE2 3.16Å; E203-Q299 PolarHBondContact OE1-NE2 3.07Å; E203-Q299 PolarHBondContact OE1-OE1 2.85Å; A295-Q299 WeakPolarHBondContact O-CB 3.3Å; A295-Q299 PolarHBondContact O-N 3.07Å; D296-Q299 PolarHBondContact O-N 2.89Å; V297-Q299 VanDerWaalsContact C-N 3.3Å; V297-Q299 PolarHBondContact O-N 2.83Å; Q299-C304 PolarHBondContact O-N 3.46Å; Q299-C304 PolarHBondContact O-SG 2.89Å
300A88.4Confident89.3Confident0 Ų04.1 Ų4.10%02%0.023CC..Iπ-helixtrans-75.3-31.2-17000000113.8G198 Y201 D296 T426G198-A300 WeakPolarHBondContact CA-O 3.16Å; G198-A300 PolarHBondContact N-O 3.45Å; Y201-A300 HydrophobicContact CD1-CB 3.83Å; Y201-A300 HydrophobicContact CG-CB 3.87Å; D296-A300 WeakPolarHBondContact O-CB 3.37Å; D296-A300 PolarHBondContact O-N 3.41Å; A300-T426 HydrophobicContact CB-CG2 3.98Å
301Y90.6Very high89.2Confident2 Ų24 Ų41%0.0082%0.023CC..Iπ-helixtrans-106.4-47-176.4-64-101.4000112.9G198 R199 V297 M356 W359 P361 F369 T426G198-Y301 VanDerWaalsContact CA-CZ 3.48Å; R199-Y301 PolarHBondContact N-OH 3.39Å; R199-Y301 VanDerWaalsContact N-OH 3.15Å; V297-Y301 HydrophobicContact CG1-CD2 4.22Å; V297-Y301 WeakPolarHBondContact O-CB 3.15Å; V297-Y301 PolarHBondContact O-N 3.48Å; Y301-M356 HydrophobicContact CE1-CB 4.3Å; Y301-M356 HydrophobicContact CE1-CG 4.48Å; Y301-M356 PolarHBondContact OH-O 3.39Å; Y301-W359 AromaticContact CD1-CE3 3.97Å; Y301-W359 HydrophobicContact CD1-CE3 3.97Å; Y301-W359 AromaticContact CD1-CZ3 3.81Å; Y301-W359 HydrophobicContact CD1-CZ3 3.81Å; Y301-W359 HydrophobicContact CE1-CE3 4.26Å; Y301-P361 HydrophobicContact CD1-CB 4.16Å; Y301-P361 HydrophobicContact CD1-CG 4Å; Y301-F369 WeakPolarHBondContact O-CE1 3.49Å; Y301-F369 WeakPolarHBondContact O-CZ 3.41Å; Y301-T426 HydrophobicContact CE2-CG2 4.15Å
302V90.9Very high89Confident1 Ų14 Ų41%0.0062%0.023CC..Iπ-helixtrans-89-57.4-171.8-169.50000112.2M298 C304 V305 S306 T310 V311 V314 F369M298-V302 WeakPolarHBondContact O-CB 3.43Å; M298-V302 PolarHBondContact O-N 2.89Å; M298-V302 HydrophobicContact SD-CG2 4.05Å; V302-C304 VanDerWaalsContact C-N 3.26Å; V302-C304 PolarHBondContact O-N 2.95Å; V302-V305 PolarHBondContact O-N 3.08Å; V302-S306 PolarHBondContact O-N 2.93Å; V302-T310 HydrophobicContact CG1-CG2 4.21Å; V302-V311 HydrophobicContact CB-CG2 4.25Å; V302-V311 HydrophobicContact CG1-CG2 3.85Å; V302-V314 HydrophobicContact CG1-CG2 4.32Å; V302-V314 HydrophobicContact CG2-CG1 4.49Å; V302-F369 HydrophobicContact CG2-CB 4.34Å; V302-F369 HydrophobicContact CG2-CD1 3.9Å; V302-F369 HydrophobicContact CG2-CE1 4.41Å; V302-F369 HydrophobicContact CG2-CG 4.13Å
303A86.9Confident89Confident0 Ų07 Ų70%03%0.034CC..Iπ-helixtrans-66.4-25.3-175.800000113.3W189 T190 M298 V305 V311W189-A303 HydrophobicContact CB-CB 4.29Å; W189-A303 HydrophobicContact CE3-CB 4.09Å; W189-A303 PolarHBondContact N-O 3.31Å; W189-A303 VanDerWaalsContact N-O 3.08Å; T190-A303 HydrophobicContact CG2-CB 4.13Å; T190-A303 PolarHBondContact N-O 3.36Å; T190-A303 WeakPolarHBondContact OG1-CB 3.44Å; T190-A303 PolarHBondContact OG1-O 3.09Å; M298-A303 WeakPolarHBondContact O-CB 3.37Å; M298-A303 PolarHBondContact O-N 3.38Å; A303-V305 PolarHBondContact O-N 3.35Å; A303-V311 HydrophobicContact CB-CG2 4.25Å
304C84.6Confident89.1Confident0 Ų06.9 Ų6.90%03%0.034CC..THydrogen-bonded Turntrans-69.5-9.3173.3-73.50000114T190 A192 K197 Y201 Q299 V302T190-C304 WeakPolarHBondContact OG1-CA 3.33Å; T190-C304 PolarHBondContact OG1-N 3.39Å; T190-C304 VanDerWaalsContact OG1-N 3.15Å; T190-C304 PolarHBondContact OG1-SG 2.95Å; T190-C304 VanDerWaalsContact OG1-SG 3.4Å; A192-C304 HydrophobicContact CB-CB 4.18Å; K197-C304 HydrophobicContact CB-CB 4.48Å; K197-C304 HydrophobicContact CD-CB 4.11Å; K197-C304 VanDerWaalsContact CE-O 3.29Å; K197-C304 WeakPolarHBondContact CE-O 3.28Å; K197-C304 HydrophobicContact CG-CB 4.12Å; K197-C304 PolarHBondContact NZ-O 3.16Å; Y201-C304 WeakPolarHBondContact CD2-SG 3.25Å; Y201-C304 WeakPolarHBondContact CE2-SG 3.29Å; Q299-C304 PolarHBondContact O-N 3.46Å; Q299-C304 PolarHBondContact O-SG 2.89Å; V302-C304 VanDerWaalsContact C-N 3.26Å; V302-C304 PolarHBondContact O-N 2.95Å
305V86.5Confident89.2Confident11 Ų116.9 Ų6.97%0.0673%0.034CC..THydrogen-bonded Turntrans-132.2-34.7-167.8176.30000112.7K197 V302 A303 P361 S362 K363 F369K197-V305 HydrophobicContact CD-CG2 3.96Å; V302-V305 PolarHBondContact O-N 3.08Å; A303-V305 PolarHBondContact O-N 3.35Å; V305-P361 HydrophobicContact CG2-CB 4.05Å; V305-P361 HydrophobicContact CG2-CG 4.2Å; V305-S362 WeakPolarHBondContact CG1-O 3.14Å; V305-K363 VanDerWaalsContact CG1-CA 3.41Å; V305-K363 HydrophobicContact CG1-CB 3.95Å; V305-K363 HydrophobicContact CG1-CG 4.44Å; V305-F369 HydrophobicContact CB-CZ 4.12Å; V305-F369 HydrophobicContact CG1-CE2 4.41Å; V305-F369 HydrophobicContact CG1-CZ 4.06Å
306S85.3Confident89.5Confident1 Ų19.2 Ų9.21%0.0074%0.044CC..SBendtrans-123.7162.2-174-59.10000112.3W189 V302 Q366W189-S306 PolarHBondContact N-O 3Å; V302-S306 PolarHBondContact O-N 2.93Å; S306-Q366 PolarHBondContact OG-NE2 3.07Å
307P83.2Confident89.7Confident16 Ų1610.2 Ų10.210%0.1045%0.051CC..  trans-62168.1173.5-23.434.6000114.3E179 T185 S309 T310E179-P307 VanDerWaalsContact CD-CB 3.47Å; E179-P307 HydrophobicContact CG-CB 4.5Å; E179-P307 VanDerWaalsContact OE1-CB 3.24Å; E179-P307 WeakPolarHBondContact OE1-CB 3.47Å; E179-P307 WeakPolarHBondContact OE2-CB 3.46Å; T185-P307 WeakPolarHBondContact O-CG 3.39Å; P307-S309 VanDerWaalsContact C-N 3.32Å; P307-S309 PolarHBondContact O-N 3.04Å; P307-T310 WeakPolarHBondContact O-CB 3.31Å; P307-T310 PolarHBondContact O-N 2.93Å; P307-T310 VanDerWaalsContact O-N 3.13Å
308Q82.9Confident89.9Confident16 Ų1610.1 Ų10.18%0.0755%0.05CC..Hα-helixtrans-63.4-33.9-176-173.5174.7-3.400112.6Y43 L175 E179 W189 T310 V311Y43-Q308 HydrophobicContact CD1-CG 4.21Å; Y43-Q308 HydrophobicContact CE1-CG 4.11Å; L175-Q308 HydrophobicContact CD1-CG 3.79Å; L175-Q308 HydrophobicContact CD2-CB 4.29Å; L175-Q308 HydrophobicContact CD2-CG 3.8Å; L175-Q308 HydrophobicContact CG-CG 4.38Å; E179-Q308 WeakPolarHBondContact OE1-CA 3.38Å; E179-Q308 PolarHBondContact OE1-N 2.97Å; W189-Q308 HydrophobicContact CB-CB 4.27Å; W189-Q308 HydrophobicContact CD2-CB 3.89Å; W189-Q308 HydrophobicContact CD2-CG 3.68Å; W189-Q308 HydrophobicContact CE3-CB 4Å; W189-Q308 HydrophobicContact CE3-CG 3.59Å; W189-Q308 HydrophobicContact CG-CB 4.02Å; W189-Q308 HydrophobicContact CG-CG 4.31Å; W189-Q308 HydrophobicContact CH2-CG 3.98Å; W189-Q308 HydrophobicContact CZ2-CG 4.07Å; W189-Q308 HydrophobicContact CZ3-CG 3.73Å; Q308-T310 VanDerWaalsContact C-N 3.3Å; Q308-T310 PolarHBondContact O-N 3.24Å; Q308-V311 PolarHBondContact O-N 3.29Å
309S86.8Confident90.1Very high4 Ų410.1 Ų10.13%0.0285%0.05CC..Hα-helixtrans-60.2-36.6174.163.40000112.9E179 P307 V311 G312 Y313E179-S309 PolarHBondContact OE1-N 2.94Å; E179-S309 PolarHBondContact OE1-OG 3.33Å; E179-S309 WeakPolarHBondContact OE2-CB 3.17Å; E179-S309 PolarHBondContact OE2-OG 3.1Å; P307-S309 VanDerWaalsContact C-N 3.32Å; P307-S309 PolarHBondContact O-N 3.04Å; S309-V311 VanDerWaalsContact C-N 3.31Å; S309-V311 PolarHBondContact O-N 3.42Å; S309-G312 WeakPolarHBondContact O-CA 3.2Å; S309-G312 PolarHBondContact O-N 3.3Å; S309-Y313 VanDerWaalsContact O-CD2 3.23Å; S309-Y313 WeakPolarHBondContact O-CD2 3.12Å; S309-Y313 PolarHBondContact O-N 3.12Å; S309-Y313 VanDerWaalsContact O-N 3.1Å
310T89.8Confident90.5Very high14 Ų1412.4 Ų12.49%0.0866%0.063CC..Hα-helixtrans-64.2-35.8-177.8-57.50000111.8V302 P307 Q308 G312 Y313 V314V302-T310 HydrophobicContact CG1-CG2 4.21Å; P307-T310 WeakPolarHBondContact O-CB 3.31Å; P307-T310 PolarHBondContact O-N 2.93Å; P307-T310 VanDerWaalsContact O-N 3.13Å; Q308-T310 VanDerWaalsContact C-N 3.3Å; Q308-T310 PolarHBondContact O-N 3.24Å; T310-G312 VanDerWaalsContact C-N 3.26Å; T310-G312 PolarHBondContact O-N 3.43Å; T310-Y313 PolarHBondContact O-N 3.36Å; T310-V314 HydrophobicContact CG2-CG2 4.37Å; T310-V314 WeakPolarHBondContact O-CG2 3.36Å; T310-V314 PolarHBondContact O-N 3.33Å
311V89.9Confident90.9Very high0 Ų013.3 Ų13.30%07%0.068CC..Hα-helixtrans-59.2-39.9172.6179.90000111.2L46 W189 M298 V302 A303 Q308 S309 V314 L315L46-V311 HydrophobicContact CD1-CG1 3.75Å; W189-V311 HydrophobicContact CE3-CG2 4.2Å; W189-V311 HydrophobicContact CZ3-CG2 4.41Å; M298-V311 HydrophobicContact CB-CG1 4.07Å; M298-V311 HydrophobicContact CG-CG1 4.11Å; M298-V311 HydrophobicContact SD-CG1 4.07Å; V302-V311 HydrophobicContact CB-CG2 4.25Å; V302-V311 HydrophobicContact CG1-CG2 3.85Å; A303-V311 HydrophobicContact CB-CG2 4.25Å; Q308-V311 PolarHBondContact O-N 3.29Å; S309-V311 VanDerWaalsContact C-N 3.31Å; S309-V311 PolarHBondContact O-N 3.42Å; V311-V314 PolarHBondContact O-N 3.24Å; V311-L315 HydrophobicContact CG1-CD1 3.78Å; V311-L315 WeakPolarHBondContact O-CB 3.24Å; V311-L315 WeakPolarHBondContact O-CD1 3.08Å; V311-L315 WeakPolarHBondContact O-CG 3.31Å; V311-L315 PolarHBondContact O-N 2.83Å
312G91.3Very high91.1Very high0 Ų013.2 Ų13.20%07%0.068CC..Hα-helixtrans-64.8-45175.400000112.9Y43 S309 T310 V314 L315 F316Y43-G312 WeakPolarHBondContact OH-CA 3.44Å; S309-G312 WeakPolarHBondContact O-CA 3.2Å; S309-G312 PolarHBondContact O-N 3.3Å; T310-G312 VanDerWaalsContact C-N 3.26Å; T310-G312 PolarHBondContact O-N 3.43Å; G312-V314 PolarHBondContact O-N 3.4Å; G312-L315 PolarHBondContact O-N 2.78Å; G312-F316 WeakPolarHBondContact O-CB 3.33Å; G312-F316 PolarHBondContact O-N 3.4Å
313Y93.5Very high91.3Very high66 Ų6614.7 Ų14.726%0.2598%0.075SC..Hα-helixtrans-64.8-37.5176.3-64.6-60.1000112.8L169 A172 S309 T310 F316 C317L169-Y313 HydrophobicContact CD1-CE1 4.27Å; A172-Y313 HydrophobicContact CB-CD1 3.78Å; A172-Y313 HydrophobicContact CB-CD2 4.12Å; A172-Y313 HydrophobicContact CB-CE1 3.65Å; A172-Y313 HydrophobicContact CB-CE2 3.99Å; A172-Y313 HydrophobicContact CB-CG 4Å; S309-Y313 VanDerWaalsContact O-CD2 3.23Å; S309-Y313 WeakPolarHBondContact O-CD2 3.12Å; S309-Y313 PolarHBondContact O-N 3.12Å; S309-Y313 VanDerWaalsContact O-N 3.1Å; T310-Y313 PolarHBondContact O-N 3.36Å; Y313-F316 WeakPolarHBondContact O-CB 3.21Å; Y313-F316 PolarHBondContact O-N 3.41Å; Y313-C317 PolarHBondContact O-N 2.75Å
314V95.2Very high91.7Very high0 Ų021.2 Ų21.20%010%0.104CC..Hα-helixtrans-65.2-40.1174.9170.40000111.4M298 V302 T310 V311 G312 C317 Y318 F369 Y370 V373M298-V314 HydrophobicContact CE-CG1 4.03Å; M298-V314 HydrophobicContact SD-CG1 4.05Å; V302-V314 HydrophobicContact CG1-CG2 4.32Å; V302-V314 HydrophobicContact CG2-CG1 4.49Å; T310-V314 HydrophobicContact CG2-CG2 4.37Å; T310-V314 WeakPolarHBondContact O-CG2 3.36Å; T310-V314 PolarHBondContact O-N 3.33Å; V311-V314 PolarHBondContact O-N 3.24Å; G312-V314 PolarHBondContact O-N 3.4Å; V314-C317 PolarHBondContact O-N 3Å; V314-Y318 PolarHBondContact O-N 3.24Å; V314-F369 HydrophobicContact CG2-CB 4.07Å; V314-Y370 HydrophobicContact CB-CD1 4.47Å; V314-Y370 HydrophobicContact CB-CE1 4.27Å; V314-Y370 HydrophobicContact CG2-CD1 3.94Å; V314-Y370 HydrophobicContact CG2-CE1 3.6Å; V314-Y370 HydrophobicContact CG2-CE2 4.49Å; V314-V373 HydrophobicContact CG1-CB 3.84Å; V314-V373 HydrophobicContact CG1-CG1 3.9Å; V314-V373 HydrophobicContact CG1-CG2 3.63Å
315L95.2Very high92.2Very high0 Ų023.6 Ų23.60%012%0.116CC..Hα-helixtrans-77.9-21.2177-69.5165.2000114.1T42 F168 M298 V311 G312 Y318 S319T42-L315 HydrophobicContact CG2-CD1 3.32Å; F168-L315 HydrophobicContact CB-CB 4.32Å; F168-L315 HydrophobicContact CD1-CB 3.54Å; F168-L315 HydrophobicContact CD1-CD1 3.96Å; F168-L315 HydrophobicContact CD1-CG 4.4Å; F168-L315 HydrophobicContact CD2-CB 3.88Å; F168-L315 HydrophobicContact CE1-CB 3.69Å; F168-L315 HydrophobicContact CE1-CD1 3.5Å; F168-L315 VanDerWaalsContact CE1-CD1 3.5Å; F168-L315 HydrophobicContact CE1-CG 4.15Å; F168-L315 HydrophobicContact CE2-CB 4.04Å; F168-L315 HydrophobicContact CG-CB 3.65Å; F168-L315 HydrophobicContact CZ-CB 3.95Å; F168-L315 HydrophobicContact CZ-CD1 4.06Å; F168-L315 HydrophobicContact CZ-CD2 4.49Å; F168-L315 HydrophobicContact CZ-CG 4.41Å; M298-L315 HydrophobicContact CE-CD2 3.62Å; M298-L315 HydrophobicContact CE-CG 4.11Å; M298-L315 HydrophobicContact CG-CD1 4.23Å; M298-L315 HydrophobicContact CG-CD2 4.3Å; M298-L315 HydrophobicContact CG-CG 4.43Å; M298-L315 HydrophobicContact SD-CD1 4.24Å; M298-L315 HydrophobicContact SD-CD2 4.04Å; M298-L315 HydrophobicContact SD-CG 3.92Å; V311-L315 HydrophobicContact CG1-CD1 3.78Å; V311-L315 WeakPolarHBondContact O-CB 3.24Å; V311-L315 WeakPolarHBondContact O-CD1 3.08Å; V311-L315 WeakPolarHBondContact O-CG 3.31Å; V311-L315 PolarHBondContact O-N 2.83Å; G312-L315 PolarHBondContact O-N 2.78Å; L315-Y318 HydrophobicContact CD2-CD1 4.31Å; L315-Y318 WeakPolarHBondContact O-CB 3.5Å; L315-S319 WeakPolarHBondContact O-CB 3.44Å; L315-S319 PolarHBondContact O-N 3.45Å; L315-S319 PolarHBondContact O-OG 2.87Å
316F95.9Very high92.4Very high50 Ų5023.1 Ų23.122%0.21911%0.113CC..Hα-helixtrans-62.5-48.4164170.4-113.2000110.2A165 F168 L169 G312 Y313 Y318 S319 L320A165-F316 HydrophobicContact CB-CD2 3.87Å; A165-F316 HydrophobicContact CB-CE2 3.98Å; A165-F316 WeakPolarHBondContact O-CD2 3.27Å; F168-F316 HydrophobicContact CB-CB 4.3Å; L169-F316 HydrophobicContact CB-CD2 3.82Å; L169-F316 HydrophobicContact CB-CE2 4.09Å; L169-F316 HydrophobicContact CB-CG 4.38Å; L169-F316 HydrophobicContact CD2-CE2 3.99Å; L169-F316 HydrophobicContact CD2-CZ 4.23Å; L169-F316 HydrophobicContact CG-CE2 4.44Å; G312-F316 WeakPolarHBondContact O-CB 3.33Å; G312-F316 PolarHBondContact O-N 3.4Å; Y313-F316 WeakPolarHBondContact O-CB 3.21Å; Y313-F316 PolarHBondContact O-N 3.41Å; F316-Y318 PolarHBondContact O-N 3.2Å; F316-S319 WeakPolarHBondContact O-CB 3.46Å; F316-S319 PolarHBondContact O-N 3.22Å; F316-L320 HydrophobicContact CD1-CD1 4.2Å; F316-L320 HydrophobicContact CD2-CG 4.45Å; F316-L320 HydrophobicContact CE1-CD1 3.63Å; F316-L320 HydrophobicContact CE1-CG 4.38Å; F316-L320 HydrophobicContact CE2-CD1 4.16Å; F316-L320 HydrophobicContact CE2-CD2 4.21Å; F316-L320 HydrophobicContact CE2-CG 4.12Å; F316-L320 HydrophobicContact CZ-CD1 3.62Å; F316-L320 HydrophobicContact CZ-CD2 4.3Å; F316-L320 HydrophobicContact CZ-CG 4.09Å; F316-L320 PolarHBondContact O-N 2.75Å
317C96.1Very high92.7Very high27 Ų2724.8 Ų24.818%0.18213%0.127CC..Hα-helixtrans-62.1-41.4175.3-67.50000112.7Y313 V314 S319 L320 T321 Y370 M374Y313-C317 PolarHBondContact O-N 2.75Å; V314-C317 PolarHBondContact O-N 3Å; C317-S319 VanDerWaalsContact C-N 3.26Å; C317-S319 PolarHBondContact O-N 2.98Å; C317-L320 PolarHBondContact O-N 2.84Å; C317-T321 PolarHBondContact O-N 3.5Å; C317-T321 PolarHBondContact O-OG1 3.37Å; C317-Y370 HydrophobicContact CB-CD1 4Å; C317-M374 HydrophobicContact CB-CG 4.19Å
318Y95.8Very high93.1Very high2 Ų229.5 Ų29.51%0.00815%0.146CC..Hα-helixtrans-50-49.3168.9-177.8-125.8000111.5W164 V293 V314 L315 F316 T321 N322 V373W164-Y318 HydrophobicContact CE3-CE1 4.49Å; W164-Y318 HydrophobicContact CZ3-CE1 4.03Å; V293-Y318 HydrophobicContact CG1-CE2 4.34Å; V314-Y318 PolarHBondContact O-N 3.24Å; L315-Y318 HydrophobicContact CD2-CD1 4.31Å; L315-Y318 WeakPolarHBondContact O-CB 3.5Å; F316-Y318 PolarHBondContact O-N 3.2Å; Y318-T321 PolarHBondContact O-N 2.74Å; Y318-N322 WeakPolarHBondContact CD1-ND2 3.38Å; Y318-N322 WeakPolarHBondContact CE1-ND2 3.49Å; Y318-N322 VanDerWaalsContact CZ-ND2 3.31Å; Y318-N322 WeakPolarHBondContact O-CB 3.47Å; Y318-N322 PolarHBondContact O-N 3.07Å; Y318-N322 PolarHBondContact O-ND2 2.73Å; Y318-V373 VanDerWaalsContact CB-CG1 3.48Å; Y318-V373 HydrophobicContact CD2-CG1 4.05Å; Y318-V373 HydrophobicContact CG-CG1 4.08Å
319S96Very high93.5Very high0 Ų028.8 Ų28.80%014%0.142CC..Hα-helixtrans-70.4-34.4-175.4-58.60000112.7W164 F168 L315 F316 C317 N322 L323W164-S319 WeakPolarHBondContact CB-OG 3.46Å; F168-S319 WeakPolarHBondContact CD2-OG 3.4Å; L315-S319 WeakPolarHBondContact O-CB 3.44Å; L315-S319 PolarHBondContact O-N 3.45Å; L315-S319 PolarHBondContact O-OG 2.87Å; F316-S319 WeakPolarHBondContact O-CB 3.46Å; F316-S319 PolarHBondContact O-N 3.22Å; C317-S319 VanDerWaalsContact C-N 3.26Å; C317-S319 PolarHBondContact O-N 2.98Å; S319-N322 PolarHBondContact O-N 3.44Å; S319-L323 WeakPolarHBondContact O-CB 3.38Å; S319-L323 PolarHBondContact O-N 3.06Å
320L96.4Very high93.4Very high51 Ų5128.8 Ų28.827%0.26714%0.142SC..Hα-helixtrans-65.3-45170.5-70.8-178.3000112.1A165 F316 C317 N322 L323 F324A165-L320 HydrophobicContact CB-CD2 4.23Å; F316-L320 HydrophobicContact CD1-CD1 4.2Å; F316-L320 HydrophobicContact CD2-CG 4.45Å; F316-L320 HydrophobicContact CE1-CD1 3.63Å; F316-L320 HydrophobicContact CE1-CG 4.38Å; F316-L320 HydrophobicContact CE2-CD1 4.16Å; F316-L320 HydrophobicContact CE2-CD2 4.21Å; F316-L320 HydrophobicContact CE2-CG 4.12Å; F316-L320 HydrophobicContact CZ-CD1 3.62Å; F316-L320 HydrophobicContact CZ-CD2 4.3Å; F316-L320 HydrophobicContact CZ-CG 4.09Å; F316-L320 PolarHBondContact O-N 2.75Å; C317-L320 PolarHBondContact O-N 2.84Å; L320-N322 VanDerWaalsContact C-N 3.31Å; L320-N322 PolarHBondContact O-N 3.41Å; L320-L323 HydrophobicContact CD2-CD2 4.33Å; L320-L323 WeakPolarHBondContact O-CB 3.41Å; L320-L323 PolarHBondContact O-N 3.34Å; L320-F324 HydrophobicContact CB-CE2 4.35Å; L320-F324 WeakPolarHBondContact O-CD2 3.46Å; L320-F324 PolarHBondContact O-N 2.82Å
321T96.2Very high93.2Very high19 Ų1931.6 Ų31.612%0.11716%0.159CC..Hα-helixtrans-65-38.7175.2-47.30000111.2C317 Y318 L323 M325 M374 F378C317-T321 PolarHBondContact O-N 3.5Å; C317-T321 PolarHBondContact O-OG1 3.37Å; Y318-T321 PolarHBondContact O-N 2.74Å; T321-L323 VanDerWaalsContact C-N 3.31Å; T321-L323 PolarHBondContact O-N 3.16Å; T321-M325 HydrophobicContact CG2-CE 4.44Å; T321-M325 HydrophobicContact CG2-CG 3.84Å; T321-M325 VanDerWaalsContact O-CB 3.24Å; T321-M325 WeakPolarHBondContact O-CB 3.44Å; T321-M325 VanDerWaalsContact O-CG 3.23Å; T321-M325 WeakPolarHBondContact O-CG 3.44Å; T321-M325 PolarHBondContact O-N 3.25Å; T321-M374 WeakPolarHBondContact CG2-O 3.48Å; T321-M374 WeakPolarHBondContact OG1-CB 3.45Å; T321-M374 WeakPolarHBondContact OG1-CG 3.18Å; T321-F378 HydrophobicContact CG2-CB 4.34Å
322N95.2Very high93Very high0 Ų032.2 Ų32.20%017%0.165CC..Hα-helixtrans-59-40.5173-70.6-42000112.5H161 Y318 S319 L320 S326 G377 R381H161-N322 HydrophobicContact CB-CB 4.39Å; Y318-N322 WeakPolarHBondContact CD1-ND2 3.38Å; Y318-N322 WeakPolarHBondContact CE1-ND2 3.49Å; Y318-N322 VanDerWaalsContact CZ-ND2 3.31Å; Y318-N322 WeakPolarHBondContact O-CB 3.47Å; Y318-N322 PolarHBondContact O-N 3.07Å; Y318-N322 PolarHBondContact O-ND2 2.73Å; S319-N322 PolarHBondContact O-N 3.44Å; L320-N322 VanDerWaalsContact C-N 3.31Å; L320-N322 PolarHBondContact O-N 3.41Å; N322-S326 WeakPolarHBondContact O-CB 2.91Å; N322-S326 PolarHBondContact O-N 3.42Å; N322-S326 VanDerWaalsContact O-N 3.1Å; N322-G377 PolarHBondContact OD1-O 3.4Å; N322-R381 HydrophobicContact CB-CG 4.29Å; N322-R381 VanDerWaalsContact CG-NH2 3.35Å; N322-R381 WeakPolarHBondContact O-CD 3.29Å; N322-R381 PolarHBondContact OD1-NE 2.83Å; N322-R381 PolarHBondContact OD1-NH2 3.17Å; N322-R381 VanDerWaalsContact OD1-NH2 3.16Å
323L95Very high92.5Very high31 Ų3132.5 Ų32.516%0.16217%0.167CC..Hα-helixtrans-63-60.7175.2175.473.1000111.2L158 H161 C162 S319 L320 T321 M325 S326 A327L158-L323 HydrophobicContact CB-CD1 4.25Å; L158-L323 HydrophobicContact CD2-CD1 3.71Å; L158-L323 HydrophobicContact CD2-CG 4.32Å; L158-L323 WeakPolarHBondContact CD2-O 3.45Å; L158-L323 WeakPolarHBondContact O-CD1 3.38Å; H161-L323 HydrophobicContact CB-CB 4.06Å; H161-L323 HydrophobicContact CB-CD1 4.41Å; C162-L323 HydrophobicContact CB-CD1 4.16Å; S319-L323 WeakPolarHBondContact O-CB 3.38Å; S319-L323 PolarHBondContact O-N 3.06Å; L320-L323 HydrophobicContact CD2-CD2 4.33Å; L320-L323 WeakPolarHBondContact O-CB 3.41Å; L320-L323 PolarHBondContact O-N 3.34Å; T321-L323 VanDerWaalsContact C-N 3.31Å; T321-L323 PolarHBondContact O-N 3.16Å; L323-M325 VanDerWaalsContact C-N 3.33Å; L323-M325 PolarHBondContact O-N 2.99Å; L323-S326 WeakPolarHBondContact O-CB 3.34Å; L323-S326 PolarHBondContact O-N 3.38Å; L323-S326 VanDerWaalsContact O-N 3.14Å; L323-A327 PolarHBondContact O-N 2.98Å
324F95.1Very high91.7Very high137 Ų13733.6 Ų33.660%0.60117%0.173SC*.Hα-helixtrans-60.9-40.9-176.9-69.5-62.6000112.6L320 S326 A327 F328L320-F324 HydrophobicContact CB-CE2 4.35Å; L320-F324 WeakPolarHBondContact O-CD2 3.46Å; L320-F324 PolarHBondContact O-N 2.82Å; F324-S326 VanDerWaalsContact C-N 3.3Å; F324-S326 PolarHBondContact O-N 3.42Å; F324-A327 PolarHBondContact O-N 2.85Å; F324-F328 PolarHBondContact O-N 3.39Å
325M93.9Very high91.2Very high50 Ų5041.2 Ų41.225%0.24621%0.208CC..Hα-helixtrans-74.5-21.1-179.7-61.4-57.5169.600112.8T321 L323 F328 I329 F378 R381T321-M325 HydrophobicContact CG2-CE 4.44Å; T321-M325 HydrophobicContact CG2-CG 3.84Å; T321-M325 VanDerWaalsContact O-CB 3.24Å; T321-M325 WeakPolarHBondContact O-CB 3.44Å; T321-M325 VanDerWaalsContact O-CG 3.23Å; T321-M325 WeakPolarHBondContact O-CG 3.44Å; T321-M325 PolarHBondContact O-N 3.25Å; L323-M325 VanDerWaalsContact C-N 3.33Å; L323-M325 PolarHBondContact O-N 2.99Å; M325-F328 HydrophobicContact SD-CB 4.33Å; M325-F328 HydrophobicContact SD-CD1 4.31Å; M325-I329 HydrophobicContact CB-CD1 4.09Å; M325-I329 VanDerWaalsContact O-CB 3.24Å; M325-I329 WeakPolarHBondContact O-CB 3.4Å; M325-I329 WeakPolarHBondContact O-CD1 3.36Å; M325-I329 WeakPolarHBondContact O-CG1 3.39Å; M325-I329 PolarHBondContact O-N 2.96Å; M325-F378 HydrophobicContact CE-CD2 3.91Å; M325-F378 HydrophobicContact CE-CE2 4.46Å; M325-F378 HydrophobicContact CG-CD2 3.91Å; M325-F378 HydrophobicContact SD-CD2 3.67Å; M325-F378 HydrophobicContact SD-CE2 4.08Å; M325-R381 HydrophobicContact CB-CB 4.09Å; M325-R381 HydrophobicContact CB-CG 4.02Å
326S91.9Very high90.6Very high1 Ų144.2 Ų44.21%0.00723%0.227CC..Hα-helixtrans-61.8-52.4166.8-172.70000111.1H157 N322 L323 F324 F328 H330H157-S326 WeakPolarHBondContact CB-OG 3.37Å; N322-S326 WeakPolarHBondContact O-CB 2.91Å; N322-S326 PolarHBondContact O-N 3.42Å; N322-S326 VanDerWaalsContact O-N 3.1Å; L323-S326 WeakPolarHBondContact O-CB 3.34Å; L323-S326 PolarHBondContact O-N 3.38Å; L323-S326 VanDerWaalsContact O-N 3.14Å; F324-S326 VanDerWaalsContact C-N 3.3Å; F324-S326 PolarHBondContact O-N 3.42Å; S326-F328 PolarHBondContact O-N 2.87Å; S326-H330 WeakPolarHBondContact O-CB 3.37Å; S326-H330 PolarHBondContact O-N 3.01Å; S326-H330 VanDerWaalsContact O-N 3.14Å; S326-H330 PolarHBondContact O-ND1 3.49Å; S326-H330 PolarHBondContact OG-CE1 2.94Å; S326-H330 PolarHBondContact OG-ND1 3.27Å
327A91Very high89.9Confident36 Ų3645 Ų4530%0.29824%0.239SC..Hα-helixtrans-59.3-46.5177.100000112.1L158 L323 F324 T331L158-A327 HydrophobicContact CD1-CB 4.15Å; L158-A327 HydrophobicContact CD2-CB 3.85Å; L323-A327 PolarHBondContact O-N 2.98Å; F324-A327 PolarHBondContact O-N 2.85Å; A327-T331 WeakPolarHBondContact O-CB 3.48Å; A327-T331 PolarHBondContact O-N 3.15Å; A327-T331 PolarHBondContact O-OG1 2.97Å
328F92.2Very high89.1Confident115 Ų11544.7 Ų44.750%0.50423%0.233SC..Hα-helixtrans-63.8-53.3-177.9-178.3-103.9000112F324 M325 S326 T331 A332F324-F328 PolarHBondContact O-N 3.39Å; M325-F328 HydrophobicContact SD-CB 4.33Å; M325-F328 HydrophobicContact SD-CD1 4.31Å; S326-F328 PolarHBondContact O-N 2.87Å; F328-T331 PolarHBondContact O-N 3.25Å; F328-A332 HydrophobicContact CE1-CB 4.3Å; F328-A332 HydrophobicContact CE2-CB 4.47Å; F328-A332 HydrophobicContact CZ-CB 4.22Å; F328-A332 VanDerWaalsContact O-CB 3.27Å; F328-A332 WeakPolarHBondContact O-CB 3.43Å; F328-A332 PolarHBondContact O-N 3.29Å
329I90.7Very high88.3Confident1 Ų146.2 Ų46.21%0.00524%0.241CC..Hα-helixtrans-67.5-43.7-173.9-63.6164.9000111M325 T331 A332 A333 R381 I382 T385 F386M325-I329 HydrophobicContact CB-CD1 4.09Å; M325-I329 VanDerWaalsContact O-CB 3.24Å; M325-I329 WeakPolarHBondContact O-CB 3.4Å; M325-I329 WeakPolarHBondContact O-CD1 3.36Å; M325-I329 WeakPolarHBondContact O-CG1 3.39Å; M325-I329 PolarHBondContact O-N 2.96Å; I329-T331 PolarHBondContact O-N 3.22Å; I329-A332 PolarHBondContact O-N 3.43Å; I329-A333 WeakPolarHBondContact O-CB 3.23Å; I329-A333 PolarHBondContact O-N 3.02Å; I329-R381 HydrophobicContact CD1-CB 3.75Å; I329-I382 HydrophobicContact CD1-CB 4.45Å; I329-I382 HydrophobicContact CD1-CG1 3.6Å; I329-I382 HydrophobicContact CG1-CG1 4.47Å; I329-T385 HydrophobicContact CG2-CG2 3.98Å; I329-F386 HydrophobicContact CG2-CE2 3.88Å
330H86.1Confident87.9Confident5 Ų549.5 Ų49.52%0.02326%0.261CS..Hα-helixtrans-62.1-26.2177.7-71.988.2000112.9H150 C154 H157 S326 F334H150-H330 PolarHBondContact O-CD2 3.35Å; C154-H330 HydrophobicContact CB-CB 3.62Å; H157-H330 AromaticContact ND1-CE1 3.96Å; H157-H330 AromaticContact ND1-NE2 3.98Å; S326-H330 WeakPolarHBondContact O-CB 3.37Å; S326-H330 PolarHBondContact O-N 3.01Å; S326-H330 VanDerWaalsContact O-N 3.14Å; S326-H330 PolarHBondContact O-ND1 3.49Å; S326-H330 PolarHBondContact OG-CE1 2.94Å; S326-H330 PolarHBondContact OG-ND1 3.27Å; H330-F334 WeakPolarHBondContact O-CD2 3.36Å; H330-F334 WeakPolarHBondContact O-CE2 3.27Å
331T84.5Confident87.4Confident72 Ų7248 Ų4844%0.44225%0.252SS..Hα-helixtrans-86.9-44.4177.3-51.40000112A327 F328 I329 A333 H335A327-T331 WeakPolarHBondContact O-CB 3.48Å; A327-T331 PolarHBondContact O-N 3.15Å; A327-T331 PolarHBondContact O-OG1 2.97Å; F328-T331 PolarHBondContact O-N 3.25Å; I329-T331 PolarHBondContact O-N 3.22Å; T331-A333 VanDerWaalsContact C-N 3.34Å; T331-A333 PolarHBondContact O-N 3.43Å; T331-H335 PolarHBondContact O-ND1 3.48Å
332A86.5Confident86.9Confident14 Ų1447.3 Ų47.312%0.11625%0.248CC..Hα-helixtrans-74.8-22.2-17800000113F328 I329 F334 H335 V336 F341F328-A332 HydrophobicContact CE1-CB 4.3Å; F328-A332 HydrophobicContact CE2-CB 4.47Å; F328-A332 HydrophobicContact CZ-CB 4.22Å; F328-A332 VanDerWaalsContact O-CB 3.27Å; F328-A332 WeakPolarHBondContact O-CB 3.43Å; F328-A332 PolarHBondContact O-N 3.29Å; I329-A332 PolarHBondContact O-N 3.43Å; A332-F334 PolarHBondContact O-N 3.02Å; A332-F334 VanDerWaalsContact O-N 3.12Å; A332-H335 PolarHBondContact O-N 3.42Å; A332-V336 PolarHBondContact O-N 3.49Å; A332-F341 HydrophobicContact CB-CZ 3.74Å
333A79.4Confident86.5Confident6 Ų654.3 Ų54.35%0.0528%0.275CS..THydrogen-bonded Turntrans-63.8-11.8176.100000114.7I329 T331 F386 R389I329-A333 WeakPolarHBondContact O-CB 3.23Å; I329-A333 PolarHBondContact O-N 3.02Å; T331-A333 VanDerWaalsContact C-N 3.34Å; T331-A333 PolarHBondContact O-N 3.43Å; A333-F386 HydrophobicContact CB-CZ 3.99Å; A333-R389 PolarHBondContact O-NH1 3.1Å
334F77.9Confident86.4Confident89 Ų8955.4 Ų55.439%0.3928%0.283SS..THydrogen-bonded Turntrans-88.4-19.5170.1-61.1-64.5000113.6H147 H150 H330 A332H147-F334 AromaticContact CD2-CE1 3.64Å; H147-F334 AromaticContact CD2-CE2 3.88Å; H147-F334 AromaticContact CD2-CZ 3.5Å; H150-F334 HydrophobicContact CB-CZ 3.81Å; H330-F334 WeakPolarHBondContact O-CD2 3.36Å; H330-F334 WeakPolarHBondContact O-CE2 3.27Å; A332-F334 PolarHBondContact O-N 3.02Å; A332-F334 VanDerWaalsContact O-N 3.12Å
335H83.5Confident86.2Confident160 Ų16048.9 Ų48.974%0.74125%0.254SS*.THydrogen-bonded Turntrans-107.7-30.7-172.5-61.790.6000113.1T331 A332T331-H335 PolarHBondContact O-ND1 3.48Å; A332-H335 PolarHBondContact O-N 3.42Å
336V83.9Confident86Confident63 Ų6348.4 Ų48.438%0.38225%0.251SS..SBendtrans-113.2144-175.8172.70000110.3A332 T340 F341A332-V336 PolarHBondContact O-N 3.49Å; V336-T340 HydrophobicContact CG1-CG2 3.9Å; V336-F341 HydrophobicContact CB-CD2 4.4Å; V336-F341 HydrophobicContact CB-CE2 3.59Å; V336-F341 HydrophobicContact CB-CZ 3.99Å; V336-F341 HydrophobicContact CG1-CD2 4.05Å; V336-F341 HydrophobicContact CG1-CE2 3.67Å; V336-F341 HydrophobicContact CG1-CZ 4.11Å
337S81.5Confident86Confident67 Ų6753.6 Ų53.647%0.46928%0.277SS..  trans-62.8142-177.3100.40000112.2M339 T340 F341S337-M339 PolarHBondContact O-N 3.32Å; S337-M339 PolarHBondContact OG-N 3.04Å; S337-T340 WeakPolarHBondContact O-CB 3.24Å; S337-T340 PolarHBondContact O-N 3.33Å; S337-T340 VanDerWaalsContact O-N 3.16Å; S337-T340 PolarHBondContact OG-N 3.12Å; S337-T340 PolarHBondContact OG-OG1 3.12Å; S337-F341 PolarHBondContact O-N 3.03Å
338R78.3Confident86.2Confident20 Ų2053.6 Ų53.68%0.07527%0.274CS..Hα-helixtrans-50.4-44.6174167.8174.460.9-140.4-5112.3T340 F341 L342 F386 E393 L449R338-T340 VanDerWaalsContact C-N 3.28Å; R338-T340 PolarHBondContact O-N 3.28Å; R338-F341 PolarHBondContact O-N 2.96Å; R338-L342 HydrophobicContact CG-CD1 3.76Å; R338-L342 HydrophobicContact CG-CG 4.22Å; R338-L342 WeakPolarHBondContact O-CG 3.24Å; R338-L342 PolarHBondContact O-N 3.45Å; R338-L342 VanDerWaalsContact O-N 3.07Å; R338-F386 HydrophobicContact CB-CD1 4.22Å; R338-F386 HydrophobicContact CB-CE1 3.9Å; R338-F386 HydrophobicContact CG-CD1 3.69Å; R338-F386 HydrophobicContact CG-CE1 3.89Å; R338-E393 IonicContact CZ-OE2 3.69Å; R338-E393 IonicContact NH1-OE2 2.76Å; R338-E393 PolarHBondContact NH1-OE2 3.11Å; R338-L449 VanDerWaalsContact CZ-CD2 3.4Å; R338-L449 VanDerWaalsContact NH2-CD2 3.29Å
339M80.1Confident86.2Confident34 Ų3448.1 Ų48.117%0.16725%0.25CC..Hα-helixtrans-68.6-31.8-173.1-47.2-41.8-137.400111.1S337 L342 W343 L446 F450S337-M339 PolarHBondContact O-N 3.32Å; S337-M339 PolarHBondContact OG-N 3.04Å; M339-L342 PolarHBondContact O-N 3.42Å; M339-L342 HydrophobicContact SD-CD1 4.27Å; M339-W343 PolarHBondContact O-N 3.13Å; M339-L446 HydrophobicContact CE-CD2 4.01Å; M339-L446 VanDerWaalsContact CE-O 3.28Å; M339-L446 WeakPolarHBondContact CE-O 3.25Å; M339-L446 HydrophobicContact SD-CD2 3.8Å; M339-F450 HydrophobicContact CE-CB 4.29Å
340T85.7Confident86.3Confident69 Ų6950 Ų5042%0.42327%0.265SS..Hα-helixtrans-58.2-47.6172.7-49.90000111.1V336 S337 R338 V344V336-T340 HydrophobicContact CG1-CG2 3.9Å; S337-T340 WeakPolarHBondContact O-CB 3.24Å; S337-T340 PolarHBondContact O-N 3.33Å; S337-T340 VanDerWaalsContact O-N 3.16Å; S337-T340 PolarHBondContact OG-N 3.12Å; S337-T340 PolarHBondContact OG-OG1 3.12Å; R338-T340 VanDerWaalsContact C-N 3.28Å; R338-T340 PolarHBondContact O-N 3.28Å; T340-V344 VanDerWaalsContact O-CG2 3.31Å; T340-V344 WeakPolarHBondContact O-CG2 3.41Å; T340-V344 PolarHBondContact O-N 3.21Å
341F87.5Confident86.6Confident18 Ų1851.4 Ų51.48%0.07928%0.281CS..Hα-helixtrans-64.8-43.3176.7-75.3-72.3000112.7A332 V336 S337 R338 W343 V344 G345 I382 F386A332-F341 HydrophobicContact CB-CZ 3.74Å; V336-F341 HydrophobicContact CB-CD2 4.4Å; V336-F341 HydrophobicContact CB-CE2 3.59Å; V336-F341 HydrophobicContact CB-CZ 3.99Å; V336-F341 HydrophobicContact CG1-CD2 4.05Å; V336-F341 HydrophobicContact CG1-CE2 3.67Å; V336-F341 HydrophobicContact CG1-CZ 4.11Å; S337-F341 PolarHBondContact O-N 3.03Å; R338-F341 PolarHBondContact O-N 2.96Å; F341-W343 PolarHBondContact O-N 3.29Å; F341-V344 PolarHBondContact O-N 2.98Å; F341-G345 PolarHBondContact O-N 3.45Å; F341-I382 HydrophobicContact CB-CG2 4.2Å; F341-I382 WeakPolarHBondContact O-CG2 3.38Å; F341-F386 HydrophobicContact CB-CD2 3.97Å; F341-F386 HydrophobicContact CB-CE2 3.35Å; F341-F386 HydrophobicContact CB-CZ 3.82Å; F341-F386 HydrophobicContact CD1-CE2 4.21Å; F341-F386 HydrophobicContact CD2-CE1 4.47Å; F341-F386 AromaticContact CD2-CE2 3.63Å; F341-F386 HydrophobicContact CD2-CE2 3.63Å; F341-F386 AromaticContact CD2-CZ 3.37Å; F341-F386 HydrophobicContact CD2-CZ 3.37Å; F341-F386 HydrophobicContact CE2-CE2 4.42Å; F341-F386 HydrophobicContact CE2-CZ 4.07Å; F341-F386 AromaticContact CG-CE2 3.49Å; F341-F386 HydrophobicContact CG-CE2 3.49Å; F341-F386 VanDerWaalsContact CG-CE2 3.49Å; F341-F386 AromaticContact CG-CZ 3.76Å; F341-F386 HydrophobicContact CG-CZ 3.76Å
342L85.3Confident87.1Confident6 Ų648.4 Ų48.43%0.03126%0.262CS..Hα-helixtrans-61.9-42179.4-67.2174.7000111.9R338 M339 G345 F346 W383 F386 M390 L446R338-L342 HydrophobicContact CG-CD1 3.76Å; R338-L342 HydrophobicContact CG-CG 4.22Å; R338-L342 WeakPolarHBondContact O-CG 3.24Å; R338-L342 PolarHBondContact O-N 3.45Å; R338-L342 VanDerWaalsContact O-N 3.07Å; M339-L342 PolarHBondContact O-N 3.42Å; M339-L342 HydrophobicContact SD-CD1 4.27Å; L342-G345 PolarHBondContact O-N 3.36Å; L342-F346 WeakPolarHBondContact O-CB 3.36Å; L342-F346 PolarHBondContact O-N 3.11Å; L342-W383 HydrophobicContact CD2-CE3 4.08Å; L342-W383 HydrophobicContact CD2-CZ3 3.82Å; L342-F386 HydrophobicContact CD2-CB 3.92Å; L342-F386 HydrophobicContact CD2-CG 4.41Å; L342-M390 HydrophobicContact CD1-SD 4.22Å; L342-L446 HydrophobicContact CB-CD2 4.31Å; L342-L446 HydrophobicContact CD1-CD1 4.5Å; L342-L446 HydrophobicContact CD1-CD2 3.8Å; L342-L446 HydrophobicContact CD1-CG 4.13Å
343W87.4Confident87.4Confident146 Ų14648.2 Ų48.255%0.55326%0.259SS*.Hα-helixtrans-64-41.9173.1-78.7117.1000112.9M339 F341 F346 I347M339-W343 PolarHBondContact O-N 3.13Å; F341-W343 PolarHBondContact O-N 3.29Å; W343-F346 HydrophobicContact CE3-CD1 4.45Å; W343-F346 HydrophobicContact CZ3-CD1 4.38Å; W343-F346 PolarHBondContact O-N 2.85Å; W343-I347 WeakPolarHBondContact O-CB 3.47Å; W343-I347 VanDerWaalsContact O-CG1 3.27Å; W343-I347 WeakPolarHBondContact O-CG1 3.46Å; W343-I347 PolarHBondContact O-N 3.28Å
344V91.4Very high88.1Confident55 Ų5552.6 Ų52.633%0.33328%0.281SS..Hα-helixtrans-62.6-42.2175166.70000111.5T340 F341 T348 F378 I382T340-V344 VanDerWaalsContact O-CG2 3.31Å; T340-V344 WeakPolarHBondContact O-CG2 3.41Å; T340-V344 PolarHBondContact O-N 3.21Å; F341-V344 PolarHBondContact O-N 2.98Å; V344-T348 WeakPolarHBondContact O-CB 3.41Å; V344-T348 WeakPolarHBondContact O-CG2 3.46Å; V344-T348 PolarHBondContact O-N 2.79Å; V344-T348 PolarHBondContact O-OG1 3.25Å; V344-F378 HydrophobicContact CG1-CE1 3.6Å; V344-F378 HydrophobicContact CG1-CZ 3.71Å; V344-I382 HydrophobicContact CG1-CD1 4.06Å
345G91.1Very high88.8Confident0 Ų051.5 Ų51.50%028%0.281CS..Hα-helixtrans-65.6-34.2175.600000113.4F341 L342 T348 Q349 W383F341-G345 PolarHBondContact O-N 3.45Å; L342-G345 PolarHBondContact O-N 3.36Å; G345-T348 PolarHBondContact O-OG1 3.07Å; G345-Q349 WeakPolarHBondContact O-CB 3.34Å; G345-Q349 PolarHBondContact O-N 2.97Å; G345-W383 PolarHBondContact O-NE1 3.38Å
346F90.4Very high89.2Confident40 Ų4043.9 Ų43.918%0.17525%0.246CC..Hα-helixtrans-70.9-51.4173.7-178.4-91.7000112.2L342 W343 T348 Q349 A350 W383 L437 I438 S441L342-F346 WeakPolarHBondContact O-CB 3.36Å; L342-F346 PolarHBondContact O-N 3.11Å; W343-F346 HydrophobicContact CE3-CD1 4.45Å; W343-F346 HydrophobicContact CZ3-CD1 4.38Å; W343-F346 PolarHBondContact O-N 2.85Å; F346-T348 PolarHBondContact O-N 2.62Å; F346-Q349 PolarHBondContact O-N 2.75Å; F346-A350 WeakPolarHBondContact O-CB 3.36Å; F346-A350 PolarHBondContact O-N 3.13Å; F346-W383 HydrophobicContact CB-CH2 4.38Å; F346-W383 HydrophobicContact CB-CZ2 4Å; F346-L437 HydrophobicContact CD2-CD2 3.95Å; F346-L437 HydrophobicContact CD2-CG 3.89Å; F346-L437 HydrophobicContact CE2-CD2 3.99Å; F346-L437 HydrophobicContact CE2-CG 3.96Å; F346-I438 HydrophobicContact CE2-CG1 4.41Å; F346-I438 HydrophobicContact CZ-CG1 4.32Å; F346-S441 WeakPolarHBondContact CE2-OG 3.33Å
347I92.2Very high89.5Confident110 Ų11045 Ų4556%0.56424%0.244SC*.Hα-helixtrans-62.2-43.5-177.6-67.5164.6000110.9W343 G351W343-I347 WeakPolarHBondContact O-CB 3.47Å; W343-I347 VanDerWaalsContact O-CG1 3.27Å; W343-I347 WeakPolarHBondContact O-CG1 3.46Å; W343-I347 PolarHBondContact O-N 3.28Å; I347-G351 PolarHBondContact O-N 3.44Å
348T93.7Very high90Very high36 Ų3646.9 Ų46.922%0.22125%0.248CC..Hα-helixtrans-66.2-40176.250.30000112.4V344 G345 F346 G351 I352 F378V344-T348 WeakPolarHBondContact O-CB 3.41Å; V344-T348 WeakPolarHBondContact O-CG2 3.46Å; V344-T348 PolarHBondContact O-N 2.79Å; V344-T348 PolarHBondContact O-OG1 3.25Å; G345-T348 PolarHBondContact O-OG1 3.07Å; F346-T348 PolarHBondContact O-N 2.62Å; T348-G351 PolarHBondContact O-N 2.93Å; T348-I352 VanDerWaalsContact O-CG2 3.32Å; T348-I352 WeakPolarHBondContact O-CG2 3.39Å; T348-I352 PolarHBondContact O-N 3.37Å; T348-I352 VanDerWaalsContact O-N 3.11Å; T348-F378 HydrophobicContact CG2-CD1 4.13Å; T348-F378 HydrophobicContact CG2-CE1 3.94Å
349Q93.1Very high90.6Very high0 Ų048 Ų480%025%0.252CS..Hα-helixtrans-70.1-35.2178.2-169.560.629.300113.1N289 G345 F346 I352 L353 S379 L437N289-Q349 PolarHBondContact ND2-NE2 3.34Å; N289-Q349 PolarHBondContact OD1-NE2 2.89Å; G345-Q349 WeakPolarHBondContact O-CB 3.34Å; G345-Q349 PolarHBondContact O-N 2.97Å; F346-Q349 PolarHBondContact O-N 2.75Å; Q349-I352 WeakPolarHBondContact O-CG2 3.23Å; Q349-L353 HydrophobicContact CG-CD1 4.48Å; Q349-L353 WeakPolarHBondContact O-CD1 3.13Å; Q349-L353 VanDerWaalsContact O-CG 3.27Å; Q349-L353 WeakPolarHBondContact O-CG 3.3Å; Q349-L353 PolarHBondContact O-N 3.43Å; Q349-S379 PolarHBondContact OE1-OG 2.91Å; Q349-L437 HydrophobicContact CB-CD1 4.19Å; Q349-L437 HydrophobicContact CB-CD2 3.94Å; Q349-L437 HydrophobicContact CG-CD1 3.74Å; Q349-L437 HydrophobicContact CG-CD2 3.8Å; Q349-L437 HydrophobicContact CG-CG 4.41Å
350A92.4Very high91Very high40 Ų4050.1 Ų50.133%0.33127%0.267SS..Hα-helixtrans-69.5-43.2173.100000111.5F346 I352 L353 L354 L437F346-A350 WeakPolarHBondContact O-CB 3.36Å; F346-A350 PolarHBondContact O-N 3.13Å; A350-I352 PolarHBondContact O-N 2.83Å; A350-L353 PolarHBondContact O-N 3.36Å; A350-L354 PolarHBondContact O-N 3.47Å; A350-L437 HydrophobicContact CB-CD2 4.49Å
351G93.8Very high91.2Very high34 Ų3447.2 Ų47.235%0.35125%0.249SC..Hα-helixtrans-60.5-43.2178.400000113.2I347 T348 L354 V355I347-G351 PolarHBondContact O-N 3.44Å; T348-G351 PolarHBondContact O-N 2.93Å; G351-L354 PolarHBondContact O-N 3.45Å; G351-V355 WeakPolarHBondContact O-CG2 3.14Å; G351-V355 PolarHBondContact O-N 3.02Å
352I94.3Very high91.1Very high9 Ų948.6 Ų48.65%0.04626%0.261CS..Hα-helixtrans-69.9-35.4178-172.5158.4000113.4T348 Q349 A350 L354 V355 M356 I372 T375 W376T348-I352 VanDerWaalsContact O-CG2 3.32Å; T348-I352 WeakPolarHBondContact O-CG2 3.39Å; T348-I352 PolarHBondContact O-N 3.37Å; T348-I352 VanDerWaalsContact O-N 3.11Å; Q349-I352 WeakPolarHBondContact O-CG2 3.23Å; A350-I352 PolarHBondContact O-N 2.83Å; I352-L354 VanDerWaalsContact C-N 3.34Å; I352-V355 PolarHBondContact O-N 3.26Å; I352-M356 HydrophobicContact CG1-CE 4.43Å; I352-M356 WeakPolarHBondContact O-CG 3.36Å; I352-M356 PolarHBondContact O-N 3.35Å; I352-I372 HydrophobicContact CD1-CB 4.13Å; I352-I372 HydrophobicContact CD1-CG2 3.64Å; I352-I372 WeakPolarHBondContact CD1-O 3.27Å; I352-I372 HydrophobicContact CG1-CG2 4Å; I352-T375 HydrophobicContact CD1-CG2 4.35Å; I352-W376 HydrophobicContact CB-CE3 4.46Å; I352-W376 HydrophobicContact CD1-CB 3.95Å; I352-W376 HydrophobicContact CD1-CE3 3.8Å; I352-W376 HydrophobicContact CG1-CE3 3.96Å; I352-W376 HydrophobicContact CG1-CZ3 4.46Å; I352-W376 HydrophobicContact CG2-CE3 3.63Å; I352-W376 HydrophobicContact CG2-CZ3 3.9Å
353L93Very high91Very high11 Ų1153.3 Ų53.36%0.05828%0.281CS..Hα-helixtrans-63.9-40.6172.4-72.3166.6000111F292 Q349 A350 M356 W357 W376 I430 V433 L437F292-L353 HydrophobicContact CE1-CD2 4.43Å; Q349-L353 HydrophobicContact CG-CD1 4.48Å; Q349-L353 WeakPolarHBondContact O-CD1 3.13Å; Q349-L353 VanDerWaalsContact O-CG 3.27Å; Q349-L353 WeakPolarHBondContact O-CG 3.3Å; Q349-L353 PolarHBondContact O-N 3.43Å; A350-L353 PolarHBondContact O-N 3.36Å; L353-M356 HydrophobicContact CD2-CE 4.14Å; L353-M356 PolarHBondContact O-N 2.97Å; L353-W357 WeakPolarHBondContact O-CB 3.19Å; L353-W357 PolarHBondContact O-N 3.01Å; L353-W376 HydrophobicContact CD2-CH2 3.93Å; L353-W376 HydrophobicContact CD2-CZ3 3.98Å; L353-W376 HydrophobicContact CG-CZ3 4.3Å; L353-I430 HydrophobicContact CD2-CG2 4.19Å; L353-V433 HydrophobicContact CD1-CG1 4.16Å; L353-V433 HydrophobicContact CD2-CB 4.31Å; L353-V433 HydrophobicContact CD2-CG1 4.08Å; L353-L437 HydrophobicContact CD1-CD2 4.49Å
354L92.7Very high90.9Very high97 Ų9753.3 Ų53.351%0.50829%0.292SS..Hα-helixtrans-64-43.7174179.362.3000112.2A350 G351 I352 M356 W357 L358A350-L354 PolarHBondContact O-N 3.47Å; G351-L354 PolarHBondContact O-N 3.45Å; I352-L354 VanDerWaalsContact C-N 3.34Å; L354-M356 PolarHBondContact O-N 3.23Å; L354-W357 HydrophobicContact CD1-CE3 4.29Å; L354-W357 PolarHBondContact O-N 2.98Å; L354-L358 HydrophobicContact CD1-CD1 4.01Å; L354-L358 HydrophobicContact CD1-CG 4.18Å; L354-L358 HydrophobicContact CG-CD1 4.03Å; L354-L358 WeakPolarHBondContact O-CG 3.35Å; L354-L358 PolarHBondContact O-N 3.35Å
355V93.3Very high90.6Very high66 Ų6653.6 Ų53.640%0.429%0.291SS..Hα-helixtrans-58.7-48.1175167.80000110.9G351 I352 W357 L358 W359 I372G351-V355 WeakPolarHBondContact O-CG2 3.14Å; G351-V355 PolarHBondContact O-N 3.02Å; I352-V355 PolarHBondContact O-N 3.26Å; V355-W357 VanDerWaalsContact C-N 3.28Å; V355-W357 PolarHBondContact O-N 3.35Å; V355-L358 PolarHBondContact O-N 3.2Å; V355-W359 VanDerWaalsContact O-CB 3.26Å; V355-W359 WeakPolarHBondContact O-CB 3.43Å; V355-W359 PolarHBondContact O-N 3.36Å; V355-I372 HydrophobicContact CG1-CD1 4.28Å; V355-I372 HydrophobicContact CG1-CG1 4.4Å
356M91.4Very high90.4Very high0 Ų057 Ų570%031%0.308CS..Hα-helixtrans-67.2-26.3178-70.1-170.7-57.500113.5F292 V297 Y301 I352 L353 L354 I372 W376 I430F292-M356 HydrophobicContact CE1-CE 3.93Å; V297-M356 HydrophobicContact CG1-SD 3.91Å; V297-M356 HydrophobicContact CG2-CE 4.13Å; V297-M356 HydrophobicContact CG2-SD 3.76Å; Y301-M356 HydrophobicContact CE1-CB 4.3Å; Y301-M356 HydrophobicContact CE1-CG 4.48Å; Y301-M356 PolarHBondContact OH-O 3.39Å; I352-M356 HydrophobicContact CG1-CE 4.43Å; I352-M356 WeakPolarHBondContact O-CG 3.36Å; I352-M356 PolarHBondContact O-N 3.35Å; L353-M356 HydrophobicContact CD2-CE 4.14Å; L353-M356 PolarHBondContact O-N 2.97Å; L354-M356 PolarHBondContact O-N 3.23Å; M356-I372 HydrophobicContact CG-CD1 4.18Å; M356-I372 HydrophobicContact CG-CG2 4.36Å; M356-I372 HydrophobicContact SD-CG2 4.01Å; M356-W376 HydrophobicContact CE-CE3 4.11Å; M356-W376 HydrophobicContact CE-CH2 4.13Å; M356-W376 HydrophobicContact CE-CZ3 3.4Å; M356-I430 HydrophobicContact CB-CD1 4.44Å
357W91.7Very high90.5Very high88 Ų8858.4 Ų58.433%0.33333%0.326SS..Hα-helixtrans-75.3-32.8174-175.481000113R199 L353 L354 V355 I430 Y431R199-W357 WeakPolarHBondContact CD-O 3.37Å; R199-W357 PolarHBondContact NH1-O 3.42Å; L353-W357 WeakPolarHBondContact O-CB 3.19Å; L353-W357 PolarHBondContact O-N 3.01Å; L354-W357 HydrophobicContact CD1-CE3 4.29Å; L354-W357 PolarHBondContact O-N 2.98Å; V355-W357 VanDerWaalsContact C-N 3.28Å; V355-W357 PolarHBondContact O-N 3.35Å; W357-I430 HydrophobicContact CB-CG2 4.42Å; W357-Y431 AromaticContact CD1-CE1 3.96Å; W357-Y431 AromaticContact NE1-CE1 3.63Å; W357-Y431 AromaticContact NE1-CZ 3.5Å; W357-Y431 PolarHBondContact NE1-OH 3.4Å
358L91Very high90.5Very high106 Ų10655.3 Ų55.356%0.55531%0.312SS*.Hα-helixtrans-84.6-42.4178.5-69.6172.7000113.3L354 V355L354-L358 HydrophobicContact CD1-CD1 4.01Å; L354-L358 HydrophobicContact CD1-CG 4.18Å; L354-L358 HydrophobicContact CG-CD1 4.03Å; L354-L358 WeakPolarHBondContact O-CG 3.35Å; L354-L358 PolarHBondContact O-N 3.35Å; V355-L358 PolarHBondContact O-N 3.2Å
359W91.2Very high90.5Very high43 Ų4353.8 Ų53.816%0.16330%0.303CS..  trans-86.4143.1-169.7177.569.9000113.1Y301 V355 P361 D365 V368 F369 I372Y301-W359 AromaticContact CD1-CE3 3.97Å; Y301-W359 HydrophobicContact CD1-CE3 3.97Å; Y301-W359 AromaticContact CD1-CZ3 3.81Å; Y301-W359 HydrophobicContact CD1-CZ3 3.81Å; Y301-W359 HydrophobicContact CE1-CE3 4.26Å; V355-W359 VanDerWaalsContact O-CB 3.26Å; V355-W359 WeakPolarHBondContact O-CB 3.43Å; V355-W359 PolarHBondContact O-N 3.36Å; W359-P361 HydrophobicContact CH2-CB 3.79Å; W359-P361 HydrophobicContact CZ2-CB 4.18Å; W359-P361 HydrophobicContact CZ3-CB 3.98Å; W359-D365 HydrophobicContact CZ2-CB 3.67Å; W359-D365 PolarHBondContact NE1-OD2 3.16Å; W359-V368 HydrophobicContact CD2-CG1 4.06Å; W359-V368 HydrophobicContact CE3-CG1 4.1Å; W359-V368 HydrophobicContact CH2-CB 3.87Å; W359-V368 HydrophobicContact CH2-CG1 3.71Å; W359-V368 HydrophobicContact CZ2-CB 3.72Å; W359-V368 HydrophobicContact CZ2-CG1 3.68Å; W359-V368 HydrophobicContact CZ2-CG2 4.25Å; W359-V368 HydrophobicContact CZ3-CG1 3.93Å; W359-F369 AromaticContact CH2-CD1 3.73Å; W359-F369 HydrophobicContact CH2-CD1 3.73Å; W359-F369 AromaticContact CH2-CE1 3.5Å; W359-F369 HydrophobicContact CH2-CE1 3.5Å; W359-F369 HydrophobicContact CH2-CZ 4.26Å; W359-F369 HydrophobicContact CZ3-CD1 4.19Å; W359-F369 HydrophobicContact CZ3-CE1 4.1Å; W359-I372 HydrophobicContact CE3-CD1 3.9Å; W359-I372 HydrophobicContact CZ3-CD1 3.72Å
360V88.7Confident90.6Very high79 Ų7956.6 Ų56.648%0.47931%0.314SS..  trans-112.8126.9174.8-179.70000107.5S362V360-S362 PolarHBondContact O-N 2.97Å
361P88.8Confident90.7Very high8 Ų858.7 Ų58.75%0.05232%0.322CS..  trans-74.7117.1-169.331-37.7000112.6K197 Y301 V305 W359 F369K197-P361 HydrophobicContact CB-CG 3.94Å; Y301-P361 HydrophobicContact CD1-CB 4.16Å; Y301-P361 HydrophobicContact CD1-CG 4Å; V305-P361 HydrophobicContact CG2-CB 4.05Å; V305-P361 HydrophobicContact CG2-CG 4.2Å; W359-P361 HydrophobicContact CH2-CB 3.79Å; W359-P361 HydrophobicContact CZ2-CB 4.18Å; W359-P361 HydrophobicContact CZ3-CB 3.98Å; P361-F369 HydrophobicContact CB-CE1 3.84Å; P361-F369 HydrophobicContact CB-CZ 4.17Å
362S86.9Confident90.7Very high46 Ų4657.6 Ų57.632%0.32231%0.308SS..  trans-94.4161.2170.5-167.70000112.3V305 V360 D364V305-S362 WeakPolarHBondContact CG1-O 3.14Å; V360-S362 PolarHBondContact O-N 2.97Å; S362-D364 VanDerWaalsContact C-N 3.35Å; S362-D364 PolarHBondContact OG-OD2 3.4Å
363K82Confident90.7Very high106 Ų10657.2 Ų57.246%0.46131%0.306SS..SBendtrans-70.6-30.9176.9-173.4171.7177.11750112.5V305 Q366V305-K363 VanDerWaalsContact CG1-CA 3.41Å; V305-K363 HydrophobicContact CG1-CB 3.95Å; V305-K363 HydrophobicContact CG1-CG 4.44Å; K363-Q366 VanDerWaalsContact O-CG 3.28Å; K363-Q366 WeakPolarHBondContact O-CG 3.45Å
364D85.3Confident90.9Very high145 Ų14560.2 Ų60.278%0.77532%0.321SS*.SBendtrans-78.6-25.6-178.1-43.5-65.4000111.8S362 Q366S362-D364 VanDerWaalsContact C-N 3.35Å; S362-D364 PolarHBondContact OG-OD2 3.4Å; D364-Q366 PolarHBondContact O-N 2.72Å
365D86.3Confident91Very high61 Ų6158 Ų5833%0.32631%0.311SS..  trans-78.326.4-177-71.6-15.9000113.9W359 A367 V368W359-D365 HydrophobicContact CZ2-CB 3.67Å; W359-D365 PolarHBondContact NE1-OD2 3.16Å; D365-A367 PolarHBondContact O-N 3.28Å; D365-V368 HydrophobicContact CB-CB 4.4Å; D365-V368 HydrophobicContact CB-CG2 3.96Å; D365-V368 WeakPolarHBondContact O-CB 3.41Å; D365-V368 PolarHBondContact O-N 3.33Å
366Q86.8Confident91.1Very high73 Ų7354.9 Ų54.934%0.34129%0.292SS..Hα-helixtrans-55.7-31.7-172.1-66-158.3-25.800113.8S306 K363 D364 V368 F369 Y370S306-Q366 PolarHBondContact OG-NE2 3.07Å; K363-Q366 VanDerWaalsContact O-CG 3.28Å; K363-Q366 WeakPolarHBondContact O-CG 3.45Å; D364-Q366 PolarHBondContact O-N 2.72Å; Q366-V368 PolarHBondContact O-N 3.34Å; Q366-F369 HydrophobicContact CB-CD2 4.36Å; Q366-F369 HydrophobicContact CG-CE2 4.4Å; Q366-F369 PolarHBondContact O-N 2.99Å; Q366-Y370 WeakPolarHBondContact O-CD2 3.19Å
367A92.1Very high91.3Very high69 Ų6954.9 Ų54.957%0.5729%0.292SS*.Hα-helixtrans-56.6-34.5174.400000113.2D365 F369 Y370 V371D365-A367 PolarHBondContact O-N 3.28Å; A367-F369 PolarHBondContact O-N 2.92Å; A367-Y370 PolarHBondContact O-N 3.48Å; A367-V371 WeakPolarHBondContact O-CG2 3.24Å; A367-V371 PolarHBondContact O-N 3.31Å; A367-V371 VanDerWaalsContact O-N 3.08Å
368V92.8Very high91.4Very high44 Ų4452.9 Ų52.927%0.26729%0.286SS..Hα-helixtrans-66.6-37.3-177.7-1760000111.1W359 D365 Q366 Y370 V371 I372W359-V368 HydrophobicContact CD2-CG1 4.06Å; W359-V368 HydrophobicContact CE3-CG1 4.1Å; W359-V368 HydrophobicContact CH2-CB 3.87Å; W359-V368 HydrophobicContact CH2-CG1 3.71Å; W359-V368 HydrophobicContact CZ2-CB 3.72Å; W359-V368 HydrophobicContact CZ2-CG1 3.68Å; W359-V368 HydrophobicContact CZ2-CG2 4.25Å; W359-V368 HydrophobicContact CZ3-CG1 3.93Å; D365-V368 HydrophobicContact CB-CB 4.4Å; D365-V368 HydrophobicContact CB-CG2 3.96Å; D365-V368 WeakPolarHBondContact O-CB 3.41Å; D365-V368 PolarHBondContact O-N 3.33Å; Q366-V368 PolarHBondContact O-N 3.34Å; V368-Y370 VanDerWaalsContact C-N 3.32Å; V368-Y370 PolarHBondContact O-N 2.96Å; V368-V371 PolarHBondContact O-N 3.46Å; V368-I372 HydrophobicContact CG1-CD1 3.78Å; V368-I372 HydrophobicContact CG1-CG1 4.19Å; V368-I372 WeakPolarHBondContact O-CB 3.07Å; V368-I372 VanDerWaalsContact O-CG1 3.3Å; V368-I372 WeakPolarHBondContact O-CG1 3.4Å; V368-I372 PolarHBondContact O-N 3.14Å
369F92.7Very high91.5Very high4 Ų447.9 Ų47.92%0.01826%0.26CS..Hα-helixtrans-56.7-45.9174.6-57.7-50.9000111.6Y301 V302 V305 V314 W359 P361 Q366 A367 V373Y301-F369 WeakPolarHBondContact O-CE1 3.49Å; Y301-F369 WeakPolarHBondContact O-CZ 3.41Å; V302-F369 HydrophobicContact CG2-CB 4.34Å; V302-F369 HydrophobicContact CG2-CD1 3.9Å; V302-F369 HydrophobicContact CG2-CE1 4.41Å; V302-F369 HydrophobicContact CG2-CG 4.13Å; V305-F369 HydrophobicContact CB-CZ 4.12Å; V305-F369 HydrophobicContact CG1-CE2 4.41Å; V305-F369 HydrophobicContact CG1-CZ 4.06Å; V314-F369 HydrophobicContact CG2-CB 4.07Å; W359-F369 AromaticContact CH2-CD1 3.73Å; W359-F369 HydrophobicContact CH2-CD1 3.73Å; W359-F369 AromaticContact CH2-CE1 3.5Å; W359-F369 HydrophobicContact CH2-CE1 3.5Å; W359-F369 HydrophobicContact CH2-CZ 4.26Å; W359-F369 HydrophobicContact CZ3-CD1 4.19Å; W359-F369 HydrophobicContact CZ3-CE1 4.1Å; P361-F369 HydrophobicContact CB-CE1 3.84Å; P361-F369 HydrophobicContact CB-CZ 4.17Å; Q366-F369 HydrophobicContact CB-CD2 4.36Å; Q366-F369 HydrophobicContact CG-CE2 4.4Å; Q366-F369 PolarHBondContact O-N 2.99Å; A367-F369 PolarHBondContact O-N 2.92Å; F369-V373 WeakPolarHBondContact O-CB 3.07Å; F369-V373 VanDerWaalsContact O-CG2 3.29Å; F369-V373 WeakPolarHBondContact O-CG2 3.3Å; F369-V373 PolarHBondContact O-N 2.77Å
370Y94.5Very high91.6Very high59 Ų5945.9 Ų45.923%0.23125%0.252CS..Hα-helixtrans-66.8-44.4178.5-61-76.1000111.8V314 C317 Q366 A367 V368 I372 V373 M374V314-Y370 HydrophobicContact CB-CD1 4.47Å; V314-Y370 HydrophobicContact CB-CE1 4.27Å; V314-Y370 HydrophobicContact CG2-CD1 3.94Å; V314-Y370 HydrophobicContact CG2-CE1 3.6Å; V314-Y370 HydrophobicContact CG2-CE2 4.49Å; C317-Y370 HydrophobicContact CB-CD1 4Å; Q366-Y370 WeakPolarHBondContact O-CD2 3.19Å; A367-Y370 PolarHBondContact O-N 3.48Å; V368-Y370 VanDerWaalsContact C-N 3.32Å; V368-Y370 PolarHBondContact O-N 2.96Å; Y370-I372 PolarHBondContact O-N 3.45Å; Y370-V373 PolarHBondContact O-N 3.28Å; Y370-M374 WeakPolarHBondContact O-CB 3.07Å; Y370-M374 WeakPolarHBondContact O-CE 3.21Å; Y370-M374 VanDerWaalsContact O-CG 3.24Å; Y370-M374 WeakPolarHBondContact O-CG 3.48Å; Y370-M374 PolarHBondContact O-N 3.02Å
371V95.2Very high91.9Very high85 Ų8542.3 Ų42.352%0.51523%0.23SC..Hα-helixtrans-62.4-44.2179.7172.60000111.8A367 V368 T375A367-V371 WeakPolarHBondContact O-CG2 3.24Å; A367-V371 PolarHBondContact O-N 3.31Å; A367-V371 VanDerWaalsContact O-N 3.08Å; V368-V371 PolarHBondContact O-N 3.46Å; V371-T375 WeakPolarHBondContact O-CB 3.29Å; V371-T375 PolarHBondContact O-N 3.37Å; V371-T375 VanDerWaalsContact O-N 3.1Å; V371-T375 PolarHBondContact O-OG1 3.35Å
372I94.5Very high92.1Very high11 Ų1141.9 Ų41.96%0.05623%0.228CC..Hα-helixtrans-55.8-58.3172-73.1174.1000109.1I352 V355 M356 W359 V368 Y370 M374 T375 W376I352-I372 HydrophobicContact CD1-CB 4.13Å; I352-I372 HydrophobicContact CD1-CG2 3.64Å; I352-I372 WeakPolarHBondContact CD1-O 3.27Å; I352-I372 HydrophobicContact CG1-CG2 4Å; V355-I372 HydrophobicContact CG1-CD1 4.28Å; V355-I372 HydrophobicContact CG1-CG1 4.4Å; M356-I372 HydrophobicContact CG-CD1 4.18Å; M356-I372 HydrophobicContact CG-CG2 4.36Å; M356-I372 HydrophobicContact SD-CG2 4.01Å; W359-I372 HydrophobicContact CE3-CD1 3.9Å; W359-I372 HydrophobicContact CZ3-CD1 3.72Å; V368-I372 HydrophobicContact CG1-CD1 3.78Å; V368-I372 HydrophobicContact CG1-CG1 4.19Å; V368-I372 WeakPolarHBondContact O-CB 3.07Å; V368-I372 VanDerWaalsContact O-CG1 3.3Å; V368-I372 WeakPolarHBondContact O-CG1 3.4Å; V368-I372 PolarHBondContact O-N 3.14Å; Y370-I372 PolarHBondContact O-N 3.45Å; I372-M374 PolarHBondContact O-N 3.33Å; I372-T375 WeakPolarHBondContact O-CB 3.22Å; I372-T375 PolarHBondContact O-N 3.41Å; I372-T375 VanDerWaalsContact O-N 3.08Å; I372-W376 PolarHBondContact O-N 3.29Å
373V94.8Very high92.3Very high1 Ų140.4 Ų40.41%0.00622%0.215CC..Hα-helixtrans-70.4-31.5-168.7170.70000113.1M298 V314 Y318 F369 Y370 G377M298-V373 HydrophobicContact CE-CG1 4.16Å; M298-V373 HydrophobicContact CE-CG2 3.61Å; V314-V373 HydrophobicContact CG1-CB 3.84Å; V314-V373 HydrophobicContact CG1-CG1 3.9Å; V314-V373 HydrophobicContact CG1-CG2 3.63Å; Y318-V373 VanDerWaalsContact CB-CG1 3.48Å; Y318-V373 HydrophobicContact CD2-CG1 4.05Å; Y318-V373 HydrophobicContact CG-CG1 4.08Å; F369-V373 WeakPolarHBondContact O-CB 3.07Å; F369-V373 VanDerWaalsContact O-CG2 3.29Å; F369-V373 WeakPolarHBondContact O-CG2 3.3Å; F369-V373 PolarHBondContact O-N 2.77Å; Y370-V373 PolarHBondContact O-N 3.28Å; V373-G377 PolarHBondContact O-N 3.41Å
374M95.6Very high92.7Very high73 Ų7336.7 Ų36.736%0.3620%0.198SC..Hα-helixtrans-65.1-45168.8-69.8-173.2-66.700111.7C317 T321 Y370 I372 W376 G377 F378C317-M374 HydrophobicContact CB-CG 4.19Å; T321-M374 WeakPolarHBondContact CG2-O 3.48Å; T321-M374 WeakPolarHBondContact OG1-CB 3.45Å; T321-M374 WeakPolarHBondContact OG1-CG 3.18Å; Y370-M374 WeakPolarHBondContact O-CB 3.07Å; Y370-M374 WeakPolarHBondContact O-CE 3.21Å; Y370-M374 VanDerWaalsContact O-CG 3.24Å; Y370-M374 WeakPolarHBondContact O-CG 3.48Å; Y370-M374 PolarHBondContact O-N 3.02Å; I372-M374 PolarHBondContact O-N 3.33Å; M374-W376 VanDerWaalsContact C-N 3.29Å; M374-W376 PolarHBondContact O-N 3.32Å; M374-G377 WeakPolarHBondContact O-CA 3.48Å; M374-G377 PolarHBondContact O-N 2.9Å; M374-F378 PolarHBondContact O-N 3.1Å
375T95.6Very high93Very high50 Ų5030.2 Ų30.231%0.30716%0.164SC..Hα-helixtrans-62.3-37.4178-56.10000111.6I352 V371 I372 F378 S379I352-T375 HydrophobicContact CD1-CG2 4.35Å; V371-T375 WeakPolarHBondContact O-CB 3.29Å; V371-T375 PolarHBondContact O-N 3.37Å; V371-T375 VanDerWaalsContact O-N 3.1Å; V371-T375 PolarHBondContact O-OG1 3.35Å; I372-T375 WeakPolarHBondContact O-CB 3.22Å; I372-T375 PolarHBondContact O-N 3.41Å; I372-T375 VanDerWaalsContact O-N 3.08Å; T375-F378 WeakPolarHBondContact O-CB 3.49Å; T375-F378 PolarHBondContact O-N 2.99Å; T375-S379 PolarHBondContact O-N 3.14Å; T375-S379 VanDerWaalsContact O-N 3.14Å; T375-S379 PolarHBondContact O-OG 2.95Å
376W94.9Very high93Very high1 Ų127.3 Ų27.30%0.00415%0.148CC..Hα-helixtrans-67.6-34.1172.4-159.6-74.7000112.8N289 F292 V293 I352 L353 M356 I372 M374 F378 S379 H380 V433N289-W376 PolarHBondContact ND2-NE1 3.23Å; N289-W376 PolarHBondContact O-NE1 3.25Å; N289-W376 WeakPolarHBondContact OD1-CZ2 3.46Å; F292-W376 AromaticContact CD1-CH2 3.46Å; F292-W376 HydrophobicContact CD1-CH2 3.46Å; F292-W376 VanDerWaalsContact CD1-CH2 3.46Å; F292-W376 AromaticContact CD1-CZ2 3.78Å; F292-W376 HydrophobicContact CD1-CZ2 3.78Å; F292-W376 HydrophobicContact CD1-CZ3 4.44Å; F292-W376 AromaticContact CE1-CH2 3.84Å; F292-W376 HydrophobicContact CE1-CH2 3.84Å; F292-W376 HydrophobicContact CE1-CZ3 4.49Å; V293-W376 HydrophobicContact CB-CD2 4.07Å; V293-W376 HydrophobicContact CB-CG 4.03Å; V293-W376 HydrophobicContact CB-CZ2 4.19Å; V293-W376 HydrophobicContact CG1-CG 4.34Å; V293-W376 VanDerWaalsContact CG1-NE1 3.32Å; V293-W376 HydrophobicContact CG2-CB 4.32Å; V293-W376 HydrophobicContact CG2-CD2 4.23Å; V293-W376 HydrophobicContact CG2-CG 3.89Å; I352-W376 HydrophobicContact CB-CE3 4.46Å; I352-W376 HydrophobicContact CD1-CB 3.95Å; I352-W376 HydrophobicContact CD1-CE3 3.8Å; I352-W376 HydrophobicContact CG1-CE3 3.96Å; I352-W376 HydrophobicContact CG1-CZ3 4.46Å; I352-W376 HydrophobicContact CG2-CE3 3.63Å; I352-W376 HydrophobicContact CG2-CZ3 3.9Å; L353-W376 HydrophobicContact CD2-CH2 3.93Å; L353-W376 HydrophobicContact CD2-CZ3 3.98Å; L353-W376 HydrophobicContact CG-CZ3 4.3Å; M356-W376 HydrophobicContact CE-CE3 4.11Å; M356-W376 HydrophobicContact CE-CH2 4.13Å; M356-W376 HydrophobicContact CE-CZ3 3.4Å; I372-W376 PolarHBondContact O-N 3.29Å; M374-W376 VanDerWaalsContact C-N 3.29Å; M374-W376 PolarHBondContact O-N 3.32Å; W376-F378 VanDerWaalsContact C-N 3.35Å; W376-S379 PolarHBondContact O-OG 3.03Å; W376-S379 VanDerWaalsContact O-OG 3.12Å; W376-H380 WeakPolarHBondContact O-CB 3.31Å; W376-H380 PolarHBondContact O-N 2.87Å; W376-V433 HydrophobicContact CH2-CG1 4.42Å
377G95.1Very high93Very high0 Ų023.9 Ų23.90%013%0.133CC..Hα-helixtrans-60.8-43.3171.600000112.2N322 V373 M374 R381N322-G377 PolarHBondContact OD1-O 3.4Å; V373-G377 PolarHBondContact O-N 3.41Å; M374-G377 WeakPolarHBondContact O-CA 3.48Å; M374-G377 PolarHBondContact O-N 2.9Å; G377-R381 WeakPolarHBondContact O-CG 3.2Å; G377-R381 PolarHBondContact O-N 3.22Å
378F94.7Very high92.7Very high47 Ų4720.8 Ų20.821%0.20611%0.106CC..Hα-helixtrans-60.7-55.9176.2174.4-100.8000112.4T321 M325 V344 T348 M374 T375 W376 H380 R381 I382T321-F378 HydrophobicContact CG2-CB 4.34Å; M325-F378 HydrophobicContact CE-CD2 3.91Å; M325-F378 HydrophobicContact CE-CE2 4.46Å; M325-F378 HydrophobicContact CG-CD2 3.91Å; M325-F378 HydrophobicContact SD-CD2 3.67Å; M325-F378 HydrophobicContact SD-CE2 4.08Å; V344-F378 HydrophobicContact CG1-CE1 3.6Å; V344-F378 HydrophobicContact CG1-CZ 3.71Å; T348-F378 HydrophobicContact CG2-CD1 4.13Å; T348-F378 HydrophobicContact CG2-CE1 3.94Å; M374-F378 PolarHBondContact O-N 3.1Å; T375-F378 WeakPolarHBondContact O-CB 3.49Å; T375-F378 PolarHBondContact O-N 2.99Å; W376-F378 VanDerWaalsContact C-N 3.35Å; F378-H380 PolarHBondContact O-N 3.44Å; F378-R381 PolarHBondContact O-N 2.88Å; F378-I382 HydrophobicContact CD1-CD1 4.2Å; F378-I382 HydrophobicContact CE1-CD1 3.71Å; F378-I382 HydrophobicContact CE2-CD1 4.32Å; F378-I382 HydrophobicContact CZ-CD1 3.79Å; F378-I382 PolarHBondContact O-N 2.95Å
379S94Very high92.3Very high0 Ų020.7 Ų20.70%010%0.101CC..Hα-helixtrans-61.4-44.2179.360.40000111.8Q349 T375 W376 R381 I382 W383Q349-S379 PolarHBondContact OE1-OG 2.91Å; T375-S379 PolarHBondContact O-N 3.14Å; T375-S379 VanDerWaalsContact O-N 3.14Å; T375-S379 PolarHBondContact O-OG 2.95Å; W376-S379 PolarHBondContact O-OG 3.03Å; W376-S379 VanDerWaalsContact O-OG 3.12Å; S379-R381 PolarHBondContact O-N 3.38Å; S379-I382 WeakPolarHBondContact O-CB 3.34Å; S379-I382 PolarHBondContact O-N 3.49Å; S379-I382 VanDerWaalsContact O-N 3.17Å; S379-W383 PolarHBondContact O-N 2.81Å
380H93.2Very high91.7Very high1 Ų121 Ų211%0.00510%0.103CC..Hα-helixtrans-64.5-36.7-179.4174.397000112.7E290 W376 F378 W383 R384E290-H380 IonicContact OE2-CE1 3.74Å; E290-H380 IonicContact OE2-NE2 4Å; W376-H380 WeakPolarHBondContact O-CB 3.31Å; W376-H380 PolarHBondContact O-N 2.87Å; F378-H380 PolarHBondContact O-N 3.44Å; H380-W383 PolarHBondContact O-N 3.19Å; H380-R384 PolarHBondContact CE1-NH2 2.99Å; H380-R384 PolarHBondContact O-N 2.59Å
381R94.1Very high91.2Very high4 Ų418.1 Ų18.12%0.0159%0.092CC..Hα-helixtrans-64.8-38.1172.8-73.5-52.8116.5-157.22.2112.4H161 N322 M325 I329 G377 F378 S379 T385H161-R381 PolarHBondContact CE1-NH1 3.14Å; H161-R381 VanDerWaalsContact NE2-CZ 3.3Å; H161-R381 PolarHBondContact NE2-NH1 3.01Å; N322-R381 HydrophobicContact CB-CG 4.29Å; N322-R381 VanDerWaalsContact CG-NH2 3.35Å; N322-R381 WeakPolarHBondContact O-CD 3.29Å; N322-R381 PolarHBondContact OD1-NE 2.83Å; N322-R381 PolarHBondContact OD1-NH2 3.17Å; N322-R381 VanDerWaalsContact OD1-NH2 3.16Å; M325-R381 HydrophobicContact CB-CB 4.09Å; M325-R381 HydrophobicContact CB-CG 4.02Å; I329-R381 HydrophobicContact CD1-CB 3.75Å; G377-R381 WeakPolarHBondContact O-CG 3.2Å; G377-R381 PolarHBondContact O-N 3.22Å; F378-R381 PolarHBondContact O-N 2.88Å; S379-R381 PolarHBondContact O-N 3.38Å; R381-T385 WeakPolarHBondContact O-CB 3.42Å; R381-T385 PolarHBondContact O-N 2.79Å; R381-T385 PolarHBondContact O-OG1 3.03Å
382I92.9Very high90.6Very high0 Ų015.3 Ų15.30%07%0.072CC..Hα-helixtrans-58.4-54.4174.5-67.6171.4000109.6I329 F341 V344 F378 S379 R384 T385 F386I329-I382 HydrophobicContact CD1-CB 4.45Å; I329-I382 HydrophobicContact CD1-CG1 3.6Å; I329-I382 HydrophobicContact CG1-CG1 4.47Å; F341-I382 HydrophobicContact CB-CG2 4.2Å; F341-I382 WeakPolarHBondContact O-CG2 3.38Å; V344-I382 HydrophobicContact CG1-CD1 4.06Å; F378-I382 HydrophobicContact CD1-CD1 4.2Å; F378-I382 HydrophobicContact CE1-CD1 3.71Å; F378-I382 HydrophobicContact CE2-CD1 4.32Å; F378-I382 HydrophobicContact CZ-CD1 3.79Å; F378-I382 PolarHBondContact O-N 2.95Å; S379-I382 WeakPolarHBondContact O-CB 3.34Å; S379-I382 PolarHBondContact O-N 3.49Å; S379-I382 VanDerWaalsContact O-N 3.17Å; I382-R384 PolarHBondContact O-N 2.8Å; I382-T385 PolarHBondContact O-N 3.16Å; I382-F386 HydrophobicContact CG2-CD2 4.07Å; I382-F386 WeakPolarHBondContact O-CB 3.48Å; I382-F386 WeakPolarHBondContact O-CD2 3.49Å; I382-F386 PolarHBondContact O-N 3.43Å
383W90.8Very high89.7Confident14 Ų1417.8 Ų17.85%0.0538%0.083CC..Hα-helixtrans-60.9-42.2-177.8-68.1118.4000113L282 I286 L342 G345 F346 S379 H380 G387 L437L282-W383 HydrophobicContact CD1-CE3 3.83Å; L282-W383 HydrophobicContact CD1-CZ3 3.91Å; I286-W383 HydrophobicContact CD1-CB 4.39Å; I286-W383 VanDerWaalsContact CD1-O 3.31Å; I286-W383 WeakPolarHBondContact CD1-O 3.49Å; I286-W383 HydrophobicContact CG1-CB 4.01Å; L342-W383 HydrophobicContact CD2-CE3 4.08Å; L342-W383 HydrophobicContact CD2-CZ3 3.82Å; G345-W383 PolarHBondContact O-NE1 3.38Å; F346-W383 HydrophobicContact CB-CH2 4.38Å; F346-W383 HydrophobicContact CB-CZ2 4Å; S379-W383 PolarHBondContact O-N 2.81Å; H380-W383 PolarHBondContact O-N 3.19Å; W383-G387 PolarHBondContact O-N 2.69Å; W383-L437 HydrophobicContact CZ2-CD1 3.89Å
384R91.1Very high88.8Confident29 Ų2919.2 Ų19.211%0.10910%0.095CC..Hα-helixtrans-64.1-55176.2-178.1146.3-63.2157.212.1112.1E290 H380 I382 F386 G387 E388 Y406E290-R384 IonicContact OE2-CZ 3.75Å; E290-R384 IonicContact OE2-NH1 3.92Å; E290-R384 PolarHBondContact OE2-NH1 3.05Å; E290-R384 IonicContact OE2-NH2 2.65Å; E290-R384 PolarHBondContact OE2-NH2 3.33Å; H380-R384 PolarHBondContact CE1-NH2 2.99Å; H380-R384 PolarHBondContact O-N 2.59Å; I382-R384 PolarHBondContact O-N 2.8Å; R384-F386 PolarHBondContact O-N 3.38Å; R384-G387 PolarHBondContact O-N 3.28Å; R384-G387 VanDerWaalsContact O-N 3.16Å; R384-E388 WeakPolarHBondContact CG-OE1 3.49Å; R384-E388 PolarHBondContact O-N 2.94Å; R384-Y406 PolarHBondContact O-OH 2.85Å
385T90.6Very high88.1Confident8 Ų816.9 Ų16.95%0.0498%0.083CC..Hα-helixtrans-62.7-40.5-174.8-45.30000111.9I329 R381 I382 R389I329-T385 HydrophobicContact CG2-CG2 3.98Å; R381-T385 WeakPolarHBondContact O-CB 3.42Å; R381-T385 PolarHBondContact O-N 2.79Å; R381-T385 PolarHBondContact O-OG1 3.03Å; I382-T385 PolarHBondContact O-N 3.16Å; T385-R389 WeakPolarHBondContact O-CB 3.15Å; T385-R389 PolarHBondContact O-N 2.76Å
386F87.3Confident87Confident1 Ų117.6 Ų17.60%0.0049%0.089CC..Hα-helixtrans-76.6-29.1176.7-79.2-75.9000113.4I329 A333 R338 F341 L342 I382 R384 R389 M390I329-F386 HydrophobicContact CG2-CE2 3.88Å; A333-F386 HydrophobicContact CB-CZ 3.99Å; R338-F386 HydrophobicContact CB-CD1 4.22Å; R338-F386 HydrophobicContact CB-CE1 3.9Å; R338-F386 HydrophobicContact CG-CD1 3.69Å; R338-F386 HydrophobicContact CG-CE1 3.89Å; F341-F386 HydrophobicContact CB-CD2 3.97Å; F341-F386 HydrophobicContact CB-CE2 3.35Å; F341-F386 HydrophobicContact CB-CZ 3.82Å; F341-F386 HydrophobicContact CD1-CE2 4.21Å; F341-F386 HydrophobicContact CD2-CE1 4.47Å; F341-F386 AromaticContact CD2-CE2 3.63Å; F341-F386 HydrophobicContact CD2-CE2 3.63Å; F341-F386 AromaticContact CD2-CZ 3.37Å; F341-F386 HydrophobicContact CD2-CZ 3.37Å; F341-F386 HydrophobicContact CE2-CE2 4.42Å; F341-F386 HydrophobicContact CE2-CZ 4.07Å; F341-F386 AromaticContact CG-CE2 3.49Å; F341-F386 HydrophobicContact CG-CE2 3.49Å; F341-F386 VanDerWaalsContact CG-CE2 3.49Å; F341-F386 AromaticContact CG-CZ 3.76Å; F341-F386 HydrophobicContact CG-CZ 3.76Å; L342-F386 HydrophobicContact CD2-CB 3.92Å; L342-F386 HydrophobicContact CD2-CG 4.41Å; I382-F386 HydrophobicContact CG2-CD2 4.07Å; I382-F386 WeakPolarHBondContact O-CB 3.48Å; I382-F386 WeakPolarHBondContact O-CD2 3.49Å; I382-F386 PolarHBondContact O-N 3.43Å; R384-F386 PolarHBondContact O-N 3.38Å; F386-R389 PolarHBondContact O-N 3.2Å; F386-M390 HydrophobicContact CB-SD 4.42Å; F386-M390 VanDerWaalsContact O-CB 3.24Å; F386-M390 WeakPolarHBondContact O-CB 3.28Å; F386-M390 WeakPolarHBondContact O-CG 3.3Å; F386-M390 PolarHBondContact O-N 2.73Å; F386-M390 VanDerWaalsContact O-SD 3.4Å
387G86.4Confident85.9Confident1 Ų124.1 Ų24.11%0.0112%0.124CC..Hα-helixtrans-58.1-52.8169.200000112.1W383 R384 R389 M390 V391W383-G387 PolarHBondContact O-N 2.69Å; R384-G387 PolarHBondContact O-N 3.28Å; R384-G387 VanDerWaalsContact O-N 3.16Å; G387-R389 PolarHBondContact O-N 3.26Å; G387-M390 PolarHBondContact O-N 3.17Å; G387-V391 VanDerWaalsContact O-CG2 3.23Å; G387-V391 WeakPolarHBondContact O-CG2 3.18Å; G387-V391 PolarHBondContact O-N 3.5Å
388E86.6Confident85Confident4 Ų427.8 Ų27.82%0.01914%0.143CC..Hα-helixtrans-58.1-47175.6-67.9170.1-171.300111.9H157 R384 M390 V391 Y392 F403 Y406H157-E388 IonicContact CE1-OE1 2.83Å; H157-E388 IonicContact CE1-OE2 3.48Å; H157-E388 PolarHBondContact CE1-OE2 3.46Å; H157-E388 IonicContact NE2-OE1 3.63Å; R384-E388 WeakPolarHBondContact CG-OE1 3.49Å; R384-E388 PolarHBondContact O-N 2.94Å; E388-M390 PolarHBondContact O-N 3.33Å; E388-V391 WeakPolarHBondContact O-CB 3.38Å; E388-V391 PolarHBondContact O-N 3.02Å; E388-Y392 PolarHBondContact O-N 2.99Å; E388-F403 HydrophobicContact CB-CE1 3.86Å; E388-F403 HydrophobicContact CB-CZ 4.08Å; E388-F403 HydrophobicContact CG-CE1 4.01Å; E388-F403 VanDerWaalsContact O-CZ 3.27Å; E388-F403 WeakPolarHBondContact O-CZ 2.99Å; E388-Y406 HydrophobicContact CG-CD1 4.25Å; E388-Y406 HydrophobicContact CG-CE1 3.54Å; E388-Y406 HydrophobicContact CG-CE2 4.47Å
389R83.5Confident84.2Confident41 Ų4127.8 Ų27.816%0.15514%0.142CC..Hα-helixtrans-62.9-39.3178.1179.5171.7173.4169.72.3113H150 A333 T385 F386 G387 V391 Y392 E393H150-R389 WeakPolarHBondContact NE2-CB 3.47Å; H150-R389 WeakPolarHBondContact NE2-CD 3.47Å; H150-R389 WeakPolarHBondContact NE2-CG 2.95Å; A333-R389 PolarHBondContact O-NH1 3.1Å; T385-R389 WeakPolarHBondContact O-CB 3.15Å; T385-R389 PolarHBondContact O-N 2.76Å; F386-R389 PolarHBondContact O-N 3.2Å; G387-R389 PolarHBondContact O-N 3.26Å; R389-V391 VanDerWaalsContact C-N 3.34Å; R389-Y392 PolarHBondContact O-N 3.31Å; R389-E393 HydrophobicContact CG-CG 4.37Å; R389-E393 IonicContact CZ-OE1 3.37Å; R389-E393 VanDerWaalsContact CZ-OE1 3.25Å; R389-E393 IonicContact NE-OE1 2.69Å; R389-E393 PolarHBondContact NE-OE1 3.3Å; R389-E393 IonicContact NH2-OE1 3.53Å; R389-E393 PolarHBondContact NH2-OE1 2.67Å; R389-E393 WeakPolarHBondContact O-CB 3.28Å; R389-E393 PolarHBondContact O-N 3.16Å
390M81.4Confident83.5Confident10 Ų1028.9 Ų28.95%0.04915%0.147CC..Hα-helixtrans-69.7-33.1179.2-74.9161.859.800111.9L279 L282 L342 F386 G387 E388 A394 V445L279-M390 HydrophobicContact CD2-CE 3.78Å; L282-M390 HydrophobicContact CD2-CE 4.16Å; L342-M390 HydrophobicContact CD1-SD 4.22Å; F386-M390 HydrophobicContact CB-SD 4.42Å; F386-M390 VanDerWaalsContact O-CB 3.24Å; F386-M390 WeakPolarHBondContact O-CB 3.28Å; F386-M390 WeakPolarHBondContact O-CG 3.3Å; F386-M390 PolarHBondContact O-N 2.73Å; F386-M390 VanDerWaalsContact O-SD 3.4Å; G387-M390 PolarHBondContact O-N 3.17Å; E388-M390 PolarHBondContact O-N 3.33Å; M390-A394 WeakPolarHBondContact O-CB 3.48Å; M390-A394 PolarHBondContact O-N 3.36Å; M390-A394 VanDerWaalsContact O-N 3.07Å; M390-V445 HydrophobicContact CE-CG1 3.42Å; M390-V445 VanDerWaalsContact CE-CG1 3.42Å
391V83.6Confident83Confident0 Ų029.5 Ų29.50%015%0.152CC..Hα-helixtrans-64-47.9170.6172.50000110.6F283 G387 E388 R389 A394 F395 S402 F403 Y406F283-V391 HydrophobicContact CE1-CG2 3.87Å; F283-V391 HydrophobicContact CE2-CG2 4.08Å; F283-V391 HydrophobicContact CZ-CG2 3.3Å; G387-V391 VanDerWaalsContact O-CG2 3.23Å; G387-V391 WeakPolarHBondContact O-CG2 3.18Å; G387-V391 PolarHBondContact O-N 3.5Å; E388-V391 WeakPolarHBondContact O-CB 3.38Å; E388-V391 PolarHBondContact O-N 3.02Å; R389-V391 VanDerWaalsContact C-N 3.34Å; V391-A394 PolarHBondContact O-N 3.27Å; V391-F395 PolarHBondContact O-N 3.19Å; V391-S402 VanDerWaalsContact CG1-C 3.44Å; V391-S402 WeakPolarHBondContact CG1-O 3.3Å; V391-F403 HydrophobicContact CB-CE2 4.26Å; V391-F403 HydrophobicContact CG1-CD2 3.71Å; V391-F403 HydrophobicContact CG1-CE2 3.8Å; V391-F403 HydrophobicContact CG1-CG 4.26Å; V391-F403 HydrophobicContact CG1-CZ 4.42Å; V391-Y406 HydrophobicContact CG2-CD2 3.89Å; V391-Y406 HydrophobicContact CG2-CG 4.16Å
392Y81.3Confident82.5Confident25 Ų2529.3 Ų29.310%0.09815%0.151CC..Hα-helixtrans-63.4-46.2178.2-169.8-82.2000112.8F131 V145 C146 A149 E388 R389 A394 F403F131-Y392 HydrophobicContact CD1-CD2 4.1Å; F131-Y392 AromaticContact CD1-CE2 3.83Å; F131-Y392 HydrophobicContact CD1-CE2 3.83Å; F131-Y392 AromaticContact CE1-CD2 3.52Å; F131-Y392 HydrophobicContact CE1-CD2 3.52Å; F131-Y392 AromaticContact CE1-CE2 3.69Å; F131-Y392 HydrophobicContact CE1-CE2 3.69Å; F131-Y392 HydrophobicContact CZ-CD2 4.18Å; V145-Y392 WeakPolarHBondContact CG1-OH 3.28Å; C146-Y392 HydrophobicContact CB-CD1 4.46Å; C146-Y392 HydrophobicContact CB-CE1 3.75Å; A149-Y392 HydrophobicContact CB-CE2 4.48Å; E388-Y392 PolarHBondContact O-N 2.99Å; R389-Y392 PolarHBondContact O-N 3.31Å; Y392-A394 VanDerWaalsContact C-N 3.33Å; Y392-A394 PolarHBondContact O-N 3.28Å; Y392-F403 HydrophobicContact CD2-CE2 4.2Å
393E76.4Confident82.2Confident63 Ų6329.5 Ų29.529%0.29415%0.152SC..Hα-helixtrans-68.3-27.6178.7-76.7-172.4-164.100113.1R338 R389 K453R338-E393 IonicContact CZ-OE2 3.69Å; R338-E393 IonicContact NH1-OE2 2.76Å; R338-E393 PolarHBondContact NH1-OE2 3.11Å; R389-E393 HydrophobicContact CG-CG 4.37Å; R389-E393 IonicContact CZ-OE1 3.37Å; R389-E393 VanDerWaalsContact CZ-OE1 3.25Å; R389-E393 IonicContact NE-OE1 2.69Å; R389-E393 PolarHBondContact NE-OE1 3.3Å; R389-E393 IonicContact NH2-OE1 3.53Å; R389-E393 PolarHBondContact NH2-OE1 2.67Å; R389-E393 WeakPolarHBondContact O-CB 3.28Å; R389-E393 PolarHBondContact O-N 3.16Å; E393-K453 IonicContact OE2-NZ 2.79Å
394A76.8Confident82.1Confident31 Ų3129.4 Ų29.426%0.25615%0.153SC..Hα-helixtrans-82.2-27.1-178.400000114.1M390 V391 Y392M390-A394 WeakPolarHBondContact O-CB 3.48Å; M390-A394 PolarHBondContact O-N 3.36Å; M390-A394 VanDerWaalsContact O-N 3.07Å; V391-A394 PolarHBondContact O-N 3.27Å; Y392-A394 VanDerWaalsContact C-N 3.33Å; Y392-A394 PolarHBondContact O-N 3.28Å
395F80.2Confident81.9Confident24 Ų2428.1 Ų28.111%0.10515%0.149CC..  trans-142.863.9-174.1-62.6-76.4000112L270 R275 L276 V391 D397 N398 W399 S402L270-F395 HydrophobicContact CD1-CD1 4.17Å; L270-F395 HydrophobicContact CD1-CE1 3.8Å; L270-F395 HydrophobicContact CD1-CZ 4.08Å; R275-F395 HydrophobicContact CB-CZ 4.05Å; L276-F395 HydrophobicContact CB-CE2 3.92Å; L276-F395 HydrophobicContact CB-CZ 4.07Å; L276-F395 HydrophobicContact CD1-CE2 4.17Å; L276-F395 HydrophobicContact CG-CE2 4.44Å; V391-F395 PolarHBondContact O-N 3.19Å; F395-D397 VanDerWaalsContact C-N 3.28Å; F395-D397 PolarHBondContact O-N 2.98Å; F395-N398 CarbonylContact O-C 3.6Å; F395-N398 PolarHBondContact O-N 3.41Å; F395-W399 PolarHBondContact O-N 3.07Å; F395-S402 WeakPolarHBondContact CB-OG 3.49Å
396P71.8Confident81.9Confident66 Ų6628 Ų2843%0.42915%0.147SC..SBendtrans-60.7-34.2-175.725-34.7000113.3
397D72.3Confident82.1Confident138 Ų13828.6 Ų28.674%0.73815%0.15SC*.THydrogen-bonded Turntrans-80.4-25.8-176.3-43.1-69.4000113.4F395F395-D397 VanDerWaalsContact C-N 3.28Å; F395-D397 PolarHBondContact O-N 2.98Å
398N76.1Confident82.4Confident77 Ų7729.3 Ų29.341%0.41215%0.154SC..THydrogen-bonded Turntrans-123.845.1-177.6-76-66.1000110.9F395 D400 S402F395-N398 CarbonylContact O-C 3.6Å; F395-N398 PolarHBondContact O-N 3.41Å; N398-D400 PolarHBondContact O-N 3.21Å; N398-S402 WeakPolarHBondContact O-CB 3.2Å; N398-S402 PolarHBondContact O-N 3.16Å; N398-S402 VanDerWaalsContact O-N 3.15Å; N398-S402 PolarHBondContact O-OG 3.44Å
399W78.7Confident82.6Confident47 Ų4729.4 Ų29.418%0.17816%0.156CC..Hα-helixtrans-59.9-31.7179.560.5-97.3000112.3A128 F131 F395 S402 F403A128-W399 HydrophobicContact CB-CH2 4.43Å; F131-W399 HydrophobicContact CB-CD2 4.08Å; F131-W399 HydrophobicContact CB-CE3 3.76Å; F131-W399 HydrophobicContact CB-CH2 3.67Å; F131-W399 HydrophobicContact CB-CZ2 3.95Å; F131-W399 HydrophobicContact CB-CZ3 3.57Å; F131-W399 HydrophobicContact CD2-CD2 4.49Å; F131-W399 AromaticContact CD2-CE3 3.65Å; F131-W399 HydrophobicContact CD2-CE3 3.65Å; F131-W399 AromaticContact CD2-CZ3 3.79Å; F131-W399 HydrophobicContact CD2-CZ3 3.79Å; F131-W399 HydrophobicContact CG-CD2 4.3Å; F131-W399 AromaticContact CG-CE3 3.85Å; F131-W399 HydrophobicContact CG-CE3 3.85Å; F131-W399 HydrophobicContact CG-CZ3 4.03Å; F395-W399 PolarHBondContact O-N 3.07Å; W399-S402 PolarHBondContact O-N 3.07Å; W399-F403 HydrophobicContact CB-CD2 4.49Å; W399-F403 WeakPolarHBondContact O-CB 3.12Å; W399-F403 WeakPolarHBondContact O-CD2 3.32Å; W399-F403 PolarHBondContact O-N 3.08Å
400D77.8Confident83.1Confident22 Ų2227.7 Ų27.712%0.11815%0.15CC..Hα-helixtrans-65.5-52.6-177.760-19.6000113.1Y252 K255 N398 S402 T404Y252-D400 PolarHBondContact OH-OD2 3.23Å; K255-D400 IonicContact NZ-OD1 2.74Å; K255-D400 PolarHBondContact NZ-OD1 3.42Å; K255-D400 IonicContact NZ-OD2 2.74Å; K255-D400 PolarHBondContact NZ-OD2 2.77Å; N398-D400 PolarHBondContact O-N 3.21Å; D400-S402 VanDerWaalsContact C-N 3.29Å; D400-S402 PolarHBondContact O-N 3.38Å; D400-T404 WeakPolarHBondContact O-CB 3.26Å; D400-T404 PolarHBondContact O-N 3.47Å; D400-T404 PolarHBondContact O-OG1 3.37Å
401S82.6Confident83.8Confident14 Ų1427.3 Ų27.310%0.09815%0.148CC..Hα-helixtrans-64.8-34.7172.9-73.60000111.8N267 T404 I405N267-S401 WeakPolarHBondContact OD1-CB 3.4Å; N267-S401 PolarHBondContact OD1-OG 3.21Å; S401-T404 WeakPolarHBondContact O-CB 3.36Å; S401-T404 PolarHBondContact O-N 3.44Å; S401-I405 WeakPolarHBondContact O-CD1 3.38Å; S401-I405 WeakPolarHBondContact O-CG1 3.34Å; S401-I405 PolarHBondContact O-N 3.39Å
402S84.1Confident84.3Confident0 Ų029.8 Ų29.80%016%0.163CC..Hα-helixtrans-72-41.3-177.6-53.70000112.5V391 F395 N398 W399 D400 I405 Y406V391-S402 VanDerWaalsContact CG1-C 3.44Å; V391-S402 WeakPolarHBondContact CG1-O 3.3Å; F395-S402 WeakPolarHBondContact CB-OG 3.49Å; N398-S402 WeakPolarHBondContact O-CB 3.2Å; N398-S402 PolarHBondContact O-N 3.16Å; N398-S402 VanDerWaalsContact O-N 3.15Å; N398-S402 PolarHBondContact O-OG 3.44Å; W399-S402 PolarHBondContact O-N 3.07Å; D400-S402 VanDerWaalsContact C-N 3.29Å; D400-S402 PolarHBondContact O-N 3.38Å; S402-I405 PolarHBondContact O-N 3.23Å; S402-Y406 PolarHBondContact O-N 3.46Å
403F86.6Confident85Confident4 Ų428.6 Ų28.62%0.01816%0.158CC..Hα-helixtrans-69.8-31.4171.7-89.1-95.8000112.6Y127 F131 E388 V391 Y392 W399 Y406 H407Y127-F403 HydrophobicContact CD1-CD1 4.12Å; Y127-F403 HydrophobicContact CD1-CE1 4.49Å; Y127-F403 HydrophobicContact CD2-CD1 4.43Å; Y127-F403 HydrophobicContact CE1-CD1 4.32Å; Y127-F403 HydrophobicContact CG-CD1 4.19Å; F131-F403 HydrophobicContact CE1-CE2 4.41Å; F131-F403 HydrophobicContact CE1-CZ 4.38Å; F131-F403 AromaticContact CE2-CD1 3.87Å; F131-F403 HydrophobicContact CE2-CD1 3.87Å; F131-F403 AromaticContact CE2-CD2 3.92Å; F131-F403 HydrophobicContact CE2-CD2 3.92Å; F131-F403 AromaticContact CE2-CE1 3.81Å; F131-F403 HydrophobicContact CE2-CE1 3.81Å; F131-F403 AromaticContact CE2-CE2 3.87Å; F131-F403 HydrophobicContact CE2-CE2 3.87Å; F131-F403 AromaticContact CE2-CG 3.94Å; F131-F403 HydrophobicContact CE2-CG 3.94Å; F131-F403 AromaticContact CE2-CZ 3.82Å; F131-F403 HydrophobicContact CE2-CZ 3.82Å; F131-F403 HydrophobicContact CZ-CD1 4.25Å; F131-F403 HydrophobicContact CZ-CD2 4.13Å; F131-F403 AromaticContact CZ-CE1 3.71Å; F131-F403 HydrophobicContact CZ-CE1 3.71Å; F131-F403 AromaticContact CZ-CE2 3.58Å; F131-F403 HydrophobicContact CZ-CE2 3.58Å; F131-F403 HydrophobicContact CZ-CG 4.45Å; F131-F403 AromaticContact CZ-CZ 3.36Å; F131-F403 HydrophobicContact CZ-CZ 3.36Å; E388-F403 HydrophobicContact CB-CE1 3.86Å; E388-F403 HydrophobicContact CB-CZ 4.08Å; E388-F403 HydrophobicContact CG-CE1 4.01Å; E388-F403 VanDerWaalsContact O-CZ 3.27Å; E388-F403 WeakPolarHBondContact O-CZ 2.99Å; V391-F403 HydrophobicContact CB-CE2 4.26Å; V391-F403 HydrophobicContact CG1-CD2 3.71Å; V391-F403 HydrophobicContact CG1-CE2 3.8Å; V391-F403 HydrophobicContact CG1-CG 4.26Å; V391-F403 HydrophobicContact CG1-CZ 4.42Å; Y392-F403 HydrophobicContact CD2-CE2 4.2Å; W399-F403 HydrophobicContact CB-CD2 4.49Å; W399-F403 WeakPolarHBondContact O-CB 3.12Å; W399-F403 WeakPolarHBondContact O-CD2 3.32Å; W399-F403 PolarHBondContact O-N 3.08Å; F403-Y406 WeakPolarHBondContact O-CB 3.37Å; F403-Y406 PolarHBondContact O-N 3.37Å; F403-H407 PolarHBondContact O-N 3.32Å
404T88Confident85.9Confident12 Ų1226.2 Ų26.27%0.07415%0.148CC..Hα-helixtrans-58.9-48169.6-59.50000110.5S69 D400 S401 H407 V408S69-T404 WeakPolarHBondContact O-CG2 3.43Å; D400-T404 WeakPolarHBondContact O-CB 3.26Å; D400-T404 PolarHBondContact O-N 3.47Å; D400-T404 PolarHBondContact O-OG1 3.37Å; S401-T404 WeakPolarHBondContact O-CB 3.36Å; S401-T404 PolarHBondContact O-N 3.44Å; T404-H407 PolarHBondContact O-N 3.16Å; T404-V408 HydrophobicContact CG2-CG2 4.47Å; T404-V408 WeakPolarHBondContact O-CB 3.33Å; T404-V408 VanDerWaalsContact O-CG2 3.22Å; T404-V408 WeakPolarHBondContact O-CG2 3.45Å; T404-V408 PolarHBondContact O-N 3.17Å
405I88.4Confident86.8Confident3 Ų325.2 Ų25.22%0.01514%0.139CC..Hα-helixtrans-69.5-34.6-180-64.2160.2000111.9L270 I271 L276 I280 S401 S402 V408 G409L270-I405 HydrophobicContact CB-CD1 3.91Å; L270-I405 HydrophobicContact CD2-CD1 3.78Å; L270-I405 HydrophobicContact CG-CD1 3.78Å; I271-I405 HydrophobicContact CD1-CG1 4.31Å; I271-I405 HydrophobicContact CG1-CD1 3.76Å; I271-I405 HydrophobicContact CG1-CG1 3.88Å; I271-I405 HydrophobicContact CG1-CG2 3.98Å; L276-I405 HydrophobicContact CD2-CB 4.09Å; L276-I405 HydrophobicContact CD2-CD1 3.53Å; L276-I405 HydrophobicContact CD2-CG1 4.4Å; L276-I405 HydrophobicContact CD2-CG2 3.76Å; L276-I405 HydrophobicContact CG-CG2 4.22Å; I280-I405 HydrophobicContact CD1-CG2 4.41Å; I280-I405 HydrophobicContact CG1-CG2 4.38Å; S401-I405 WeakPolarHBondContact O-CD1 3.38Å; S401-I405 WeakPolarHBondContact O-CG1 3.34Å; S401-I405 PolarHBondContact O-N 3.39Å; S402-I405 PolarHBondContact O-N 3.23Å; I405-V408 PolarHBondContact O-N 3.23Å; I405-G409 PolarHBondContact O-N 2.9Å
406Y89.8Confident87.4Confident5 Ų527 Ų272%0.0215%0.148CC..Hα-helixtrans-56.6-50.3170.1173.8-103.7000112.1F283 I286 R384 E388 V391 S402 F403 G409 C410F283-Y406 AromaticContact CD1-CD2 3.52Å; F283-Y406 HydrophobicContact CD1-CD2 3.52Å; F283-Y406 AromaticContact CD1-CE2 3.8Å; F283-Y406 HydrophobicContact CD1-CE2 3.8Å; F283-Y406 HydrophobicContact CD2-CD2 4.2Å; F283-Y406 AromaticContact CE1-CD2 3.61Å; F283-Y406 HydrophobicContact CE1-CD2 3.61Å; F283-Y406 HydrophobicContact CE1-CE2 4.08Å; F283-Y406 HydrophobicContact CE2-CD2 4.26Å; F283-Y406 AromaticContact CG-CD2 3.85Å; F283-Y406 HydrophobicContact CG-CD2 3.85Å; F283-Y406 HydrophobicContact CG-CE2 4.38Å; F283-Y406 AromaticContact CZ-CD2 3.98Å; F283-Y406 HydrophobicContact CZ-CD2 3.98Å; I286-Y406 HydrophobicContact CD1-CE2 4.49Å; R384-Y406 PolarHBondContact O-OH 2.85Å; E388-Y406 HydrophobicContact CG-CD1 4.25Å; E388-Y406 HydrophobicContact CG-CE1 3.54Å; E388-Y406 HydrophobicContact CG-CE2 4.47Å; V391-Y406 HydrophobicContact CG2-CD2 3.89Å; V391-Y406 HydrophobicContact CG2-CG 4.16Å; S402-Y406 PolarHBondContact O-N 3.46Å; F403-Y406 WeakPolarHBondContact O-CB 3.37Å; F403-Y406 PolarHBondContact O-N 3.37Å; Y406-G409 PolarHBondContact O-N 3.4Å; Y406-C410 PolarHBondContact O-N 2.87Å; Y406-C410 PolarHBondContact O-SG 3.04Å
407H90.7Very high88.4Confident14 Ų1424 Ų247%0.06513%0.13CC..Hα-helixtrans-66.7-38.7179.9-178.461000112.3S69 F123 F403 T404 C410 T411S69-H407 PolarHBondContact OG-CD2 2.79Å; S69-H407 VanDerWaalsContact OG-CD2 3.27Å; F123-H407 AromaticContact CD2-CE1 3.09Å; F123-H407 WeakPolarHBondContact CD2-CE1 3.22Å; F123-H407 AromaticContact CD2-ND1 3.98Å; F123-H407 AromaticContact CD2-NE2 3.31Å; F123-H407 VanDerWaalsContact CD2-NE2 3.31Å; F123-H407 WeakPolarHBondContact CD2-NE2 3.33Å; F123-H407 AromaticContact CE2-CE1 3.64Å; F123-H407 AromaticContact CG-CE1 3.39Å; F123-H407 WeakPolarHBondContact CG-CE1 3.3Å; F123-H407 AromaticContact CG-ND1 3.83Å; F123-H407 AromaticContact CG-NE2 3.7Å; F403-H407 PolarHBondContact O-N 3.32Å; T404-H407 PolarHBondContact O-N 3.16Å; H407-C410 PolarHBondContact O-N 3.41Å; H407-T411 WeakPolarHBondContact CE1-CG2 3.45Å; H407-T411 WeakPolarHBondContact O-CB 3.29Å; H407-T411 PolarHBondContact O-N 3.29Å; H407-T411 PolarHBondContact O-OG1 3.01Å
408V92.8Very high89.4Confident16 Ų1617.4 Ų17.410%0.09710%0.095CC..Hα-helixtrans-60-47.1172.3167.40000111.4A66 L70 T404 I405 C410 T411 V412A66-V408 HydrophobicContact CB-CG1 4.34Å; L70-V408 HydrophobicContact CD1-CG1 4.49Å; L70-V408 HydrophobicContact CD2-CG2 3.92Å; L70-V408 HydrophobicContact CG-CG2 3.86Å; T404-V408 HydrophobicContact CG2-CG2 4.47Å; T404-V408 WeakPolarHBondContact O-CB 3.33Å; T404-V408 VanDerWaalsContact O-CG2 3.22Å; T404-V408 WeakPolarHBondContact O-CG2 3.45Å; T404-V408 PolarHBondContact O-N 3.17Å; I405-V408 PolarHBondContact O-N 3.23Å; V408-C410 PolarHBondContact O-N 3.33Å; V408-T411 WeakPolarHBondContact CA-OG1 3.41Å; V408-T411 PolarHBondContact O-N 3.09Å; V408-T411 PolarHBondContact O-OG1 3.37Å; V408-V412 HydrophobicContact CG1-CG2 4.44Å; V408-V412 WeakPolarHBondContact O-CB 3.42Å; V408-V412 VanDerWaalsContact O-CG2 3.3Å; V408-V412 WeakPolarHBondContact O-CG2 3.48Å; V408-V412 PolarHBondContact O-N 3.13Å
409G92.4Very high90.1Very high5 Ų518.1 Ų18.15%0.05210%0.098CC..Hα-helixtrans-59.3-45.5176.200000112.5I284 I405 Y406 G413I284-G409 WeakPolarHBondContact CA-O 3.11Å; I405-G409 PolarHBondContact O-N 2.9Å; Y406-G409 PolarHBondContact O-N 3.4Å; G409-G413 PolarHBondContact O-N 3.28Å
410C94Very high90.6Very high5 Ų518.8 Ų18.83%0.03410%0.104CC..Hα-helixtrans-64.3-42.5177.3-650000112.6F283 G287 Y406 H407 V408 G413 M414F283-C410 WeakPolarHBondContact O-CA 3.49Å; G287-C410 VanDerWaalsContact CA-O 3.27Å; G287-C410 WeakPolarHBondContact CA-O 3.22Å; Y406-C410 PolarHBondContact O-N 2.87Å; Y406-C410 PolarHBondContact O-SG 3.04Å; H407-C410 PolarHBondContact O-N 3.41Å; V408-C410 PolarHBondContact O-N 3.33Å; C410-G413 PolarHBondContact O-N 3.46Å; C410-M414 WeakPolarHBondContact O-CG 3.43Å; C410-M414 PolarHBondContact O-N 3.07Å
411T94.7Very high90.9Very high2 Ų217.8 Ų17.81%0.01210%0.099CC..Hα-helixtrans-73.2-36.3-17944.60000112.8Y62 H407 V408 G413 M414 S415Y62-T411 HydrophobicContact CD1-CG2 3.97Å; Y62-T411 HydrophobicContact CE1-CG2 4.48Å; H407-T411 WeakPolarHBondContact CE1-CG2 3.45Å; H407-T411 WeakPolarHBondContact O-CB 3.29Å; H407-T411 PolarHBondContact O-N 3.29Å; H407-T411 PolarHBondContact O-OG1 3.01Å; V408-T411 WeakPolarHBondContact CA-OG1 3.41Å; V408-T411 PolarHBondContact O-N 3.09Å; V408-T411 PolarHBondContact O-OG1 3.37Å; T411-G413 VanDerWaalsContact C-N 3.32Å; T411-G413 PolarHBondContact O-N 2.86Å; T411-M414 PolarHBondContact O-N 3.08Å; T411-S415 PolarHBondContact O-N 2.93Å
412V95.4Very high90.9Very high52 Ų5217.9 Ų17.932%0.31510%0.099SC..Hα-helixtrans-59.5-44.1168.1169.60000110.7A66 V408 M414 S415 I416A66-V412 HydrophobicContact CB-CG2 3.79Å; V408-V412 HydrophobicContact CG1-CG2 4.44Å; V408-V412 WeakPolarHBondContact O-CB 3.42Å; V408-V412 VanDerWaalsContact O-CG2 3.3Å; V408-V412 WeakPolarHBondContact O-CG2 3.48Å; V408-V412 PolarHBondContact O-N 3.13Å; V412-M414 VanDerWaalsContact C-N 3.35Å; V412-M414 PolarHBondContact O-N 3.44Å; V412-S415 PolarHBondContact O-N 2.87Å; V412-I416 HydrophobicContact CG1-CD1 3.85Å; V412-I416 WeakPolarHBondContact O-CG1 3.23Å; V412-I416 PolarHBondContact O-N 3.15Å
413G94.5Very high90.8Very high0 Ų024.3 Ų24.30%013%0.127CC..Hα-helixtrans-59.5-40.7173.700000113.7I284 I288 G409 C410 T411 I416 G417I284-G413 WeakPolarHBondContact O-CA 3.32Å; I288-G413 WeakPolarHBondContact CG1-O 3.38Å; I288-G413 PolarHBondContact N-O 2.99Å; G409-G413 PolarHBondContact O-N 3.28Å; C410-G413 PolarHBondContact O-N 3.46Å; T411-G413 VanDerWaalsContact C-N 3.32Å; T411-G413 PolarHBondContact O-N 2.86Å; G413-I416 PolarHBondContact O-N 3.36Å; G413-G417 PolarHBondContact O-N 3.3Å
414M95.2Very high90.6Very high14 Ų1425.6 Ų25.67%0.06914%0.141CC..Hα-helixtrans-64.9-42.8175-67.1177.5-170.200112.1Y62 E290 V291 C410 T411 V412 I416 G417 F418Y62-M414 HydrophobicContact CD1-CB 4.08Å; Y62-M414 HydrophobicContact CD1-SD 4.04Å; Y62-M414 HydrophobicContact CD2-CB 3.99Å; Y62-M414 HydrophobicContact CE1-CB 4.38Å; Y62-M414 HydrophobicContact CE1-SD 3.56Å; Y62-M414 VanDerWaalsContact CE1-SD 3.56Å; Y62-M414 HydrophobicContact CE2-CB 4.31Å; Y62-M414 HydrophobicContact CG-CB 3.88Å; E290-M414 HydrophobicContact CB-CE 4.28Å; E290-M414 HydrophobicContact CG-CE 4.5Å; E290-M414 WeakPolarHBondContact OE2-CE 3.45Å; V291-M414 HydrophobicContact CG2-CB 3.73Å; V291-M414 HydrophobicContact CG2-CG 3.86Å; C410-M414 WeakPolarHBondContact O-CG 3.43Å; C410-M414 PolarHBondContact O-N 3.07Å; T411-M414 PolarHBondContact O-N 3.08Å; V412-M414 VanDerWaalsContact C-N 3.35Å; V412-M414 PolarHBondContact O-N 3.44Å; M414-I416 PolarHBondContact O-N 2.92Å; M414-G417 PolarHBondContact O-N 2.83Å; M414-F418 WeakPolarHBondContact O-CD2 3.43Å; M414-F418 PolarHBondContact O-N 2.91Å
415S96.1Very high90.4Very high9 Ų928.5 Ų28.56%0.06315%0.153CC..Hα-helixtrans-59.3-45.9174.8162.90000111.9S59 V63 T411 V412 G417 F418 L419S59-S415 PolarHBondContact O-OG 3.22Å; S59-S415 PolarHBondContact OG-O 2.74Å; S59-S415 PolarHBondContact OG-OG 3.5Å; V63-S415 WeakPolarHBondContact CG2-OG 3.24Å; T411-S415 PolarHBondContact O-N 2.93Å; V412-S415 PolarHBondContact O-N 2.87Å; S415-G417 VanDerWaalsContact C-N 3.32Å; S415-G417 PolarHBondContact O-N 3.4Å; S415-F418 PolarHBondContact O-N 3.34Å; S415-L419 WeakPolarHBondContact O-CB 3.16Å; S415-L419 PolarHBondContact O-N 3.45Å
416I94.1Very high90.4Very high61 Ų6128.4 Ų28.431%0.31315%0.152SC..Hα-helixtrans-59.3-44.4177-68.6165.3000110.3I284 I288 V412 G413 M414 L419 M420I284-I416 HydrophobicContact CG2-CD1 4.2Å; I288-I416 HydrophobicContact CD1-CG2 4.06Å; I288-I416 HydrophobicContact CG1-CB 4.44Å; I288-I416 HydrophobicContact CG1-CG2 4.33Å; V412-I416 HydrophobicContact CG1-CD1 3.85Å; V412-I416 WeakPolarHBondContact O-CG1 3.23Å; V412-I416 PolarHBondContact O-N 3.15Å; G413-I416 PolarHBondContact O-N 3.36Å; M414-I416 PolarHBondContact O-N 2.92Å; I416-L419 PolarHBondContact O-N 3.44Å; I416-M420 HydrophobicContact CG2-CG 4.3Å; I416-M420 HydrophobicContact CG2-SD 3.83Å; I416-M420 WeakPolarHBondContact O-CB 3.28Å; I416-M420 VanDerWaalsContact O-CG 3.28Å; I416-M420 WeakPolarHBondContact O-CG 3.3Å; I416-M420 PolarHBondContact O-N 3.32Å
417G92.4Very high90.3Very high4 Ų429.9 Ų29.94%0.04116%0.16CC..Hα-helixtrans-56.7-51.5174.800000113.3G413 M414 S415 L419 M420 K421G413-G417 PolarHBondContact O-N 3.3Å; M414-G417 PolarHBondContact O-N 2.83Å; S415-G417 VanDerWaalsContact C-N 3.32Å; S415-G417 PolarHBondContact O-N 3.4Å; G417-L419 VanDerWaalsContact C-N 3.32Å; G417-L419 PolarHBondContact O-N 3.33Å; G417-M420 PolarHBondContact O-N 3.21Å; G417-K421 PolarHBondContact O-N 2.99Å
418F92Very high90.2Very high0 Ų035.7 Ų35.70%018%0.182CC..Hα-helixtrans-67.5-31179-73.3-63.8000112.9R41 S55 L58 Y62 V291 A295 M414 S415R41-F418 HydrophobicContact CG-CZ 4Å; S55-F418 WeakPolarHBondContact CB-O 3.24Å; L58-F418 HydrophobicContact CB-CB 4.3Å; L58-F418 HydrophobicContact CB-CD1 4.04Å; L58-F418 HydrophobicContact CB-CD2 3.99Å; L58-F418 HydrophobicContact CB-CE1 4.41Å; L58-F418 HydrophobicContact CB-CE2 4.37Å; L58-F418 HydrophobicContact CB-CG 3.84Å; L58-F418 HydrophobicContact CD1-CD1 3.96Å; L58-F418 HydrophobicContact CD1-CE1 3.73Å; L58-F418 HydrophobicContact CD1-CZ 4.14Å; Y62-F418 AromaticContact CD2-CD2 3.79Å; Y62-F418 HydrophobicContact CD2-CD2 3.79Å; Y62-F418 AromaticContact CD2-CE2 3.8Å; Y62-F418 HydrophobicContact CD2-CE2 3.8Å; Y62-F418 AromaticContact CE2-CD2 3.97Å; Y62-F418 HydrophobicContact CE2-CD2 3.97Å; Y62-F418 AromaticContact CE2-CE2 3.48Å; Y62-F418 HydrophobicContact CE2-CE2 3.48Å; Y62-F418 VanDerWaalsContact CE2-CE2 3.48Å; Y62-F418 HydrophobicContact CE2-CZ 4.48Å; V291-F418 HydrophobicContact CB-CD2 4.5Å; V291-F418 HydrophobicContact CB-CE2 4.21Å; V291-F418 HydrophobicContact CB-CZ 4.29Å; V291-F418 HydrophobicContact CG1-CD1 3.67Å; V291-F418 HydrophobicContact CG1-CD2 3.89Å; V291-F418 HydrophobicContact CG1-CE1 3.59Å; V291-F418 HydrophobicContact CG1-CE2 3.81Å; V291-F418 HydrophobicContact CG1-CG 3.8Å; V291-F418 HydrophobicContact CG1-CZ 3.67Å; V291-F418 HydrophobicContact CG2-CD2 3.76Å; V291-F418 HydrophobicContact CG2-CE2 3.32Å; V291-F418 HydrophobicContact CG2-CZ 3.78Å; A295-F418 HydrophobicContact CB-CE1 4.1Å; M414-F418 WeakPolarHBondContact O-CD2 3.43Å; M414-F418 PolarHBondContact O-N 2.91Å; S415-F418 PolarHBondContact O-N 3.34Å
419L91.3Very high90.1Very high92 Ų9235.3 Ų35.348%0.48218%0.179SC..Hα-helixtrans-71.5-34.1174.1-172.362.5000112.3S415 I416 G417 P422 F423S415-L419 WeakPolarHBondContact O-CB 3.16Å; S415-L419 PolarHBondContact O-N 3.45Å; I416-L419 PolarHBondContact O-N 3.44Å; G417-L419 VanDerWaalsContact C-N 3.32Å; G417-L419 PolarHBondContact O-N 3.33Å; L419-P422 WeakPolarHBondContact O-CD 3.29Å; L419-F423 WeakPolarHBondContact O-CD2 3.28Å; L419-F423 VanDerWaalsContact O-CE2 3.3Å; L419-F423 WeakPolarHBondContact O-CE2 3.27Å
420M88.9Confident90Very high61 Ų6135.4 Ų35.430%0.318%0.178SC..Hα-helixtrans-74.9-28.7176-75.8179.266.300113.5I416 G417 F423 T432I416-M420 HydrophobicContact CG2-CG 4.3Å; I416-M420 HydrophobicContact CG2-SD 3.83Å; I416-M420 WeakPolarHBondContact O-CB 3.28Å; I416-M420 VanDerWaalsContact O-CG 3.28Å; I416-M420 WeakPolarHBondContact O-CG 3.3Å; I416-M420 PolarHBondContact O-N 3.32Å; G417-M420 PolarHBondContact O-N 3.21Å; M420-F423 PolarHBondContact O-N 3.44Å; M420-T432 HydrophobicContact CE-CG2 3.89Å
421K85.9Confident89.8Confident1 Ų140.2 Ų40.20%0.00420%0.197CC..THydrogen-bonded Turntrans-44.8-52.2-177.3177.7177-177.4-75.70114.5S45 E203 A295 G417 F423 K429S45-K421 WeakPolarHBondContact O-CE 3.42Å; S45-K421 PolarHBondContact O-NZ 3.3Å; E203-K421 IonicContact OE1-NZ 3.96Å; E203-K421 PolarHBondContact OE1-NZ 3.02Å; E203-K421 IonicContact OE2-NZ 2.67Å; E203-K421 PolarHBondContact OE2-NZ 2.97Å; A295-K421 HydrophobicContact CB-CD 3.99Å; G417-K421 PolarHBondContact O-N 2.99Å; K421-F423 PolarHBondContact O-N 3.2Å; K421-F423 VanDerWaalsContact O-N 3.15Å; K421-K429 WeakPolarHBondContact O-CE 3.3Å; K421-K429 PolarHBondContact O-NZ 2.92Å
422P82Confident89.4Confident16 Ų1642.6 Ų42.610%0.10421%0.211CC..THydrogen-bonded Turntrans-73.1-0.7-178.328.2-36.8000115.4N52 L419N52-P422 HydrophobicContact CB-CB 3.8Å; N52-P422 HydrophobicContact CB-CG 4.14Å; N52-P422 VanDerWaalsContact ND2-CB 3.33Å; N52-P422 WeakPolarHBondContact ND2-CB 3.49Å; L419-P422 WeakPolarHBondContact O-CD 3.29Å
423F82.6Confident89.1Confident134 Ų13440.4 Ų40.459%0.58820%0.198SC*.SBendtrans-114.3132.8-174.1-58.8-66.5000113.2L419 M420 K421 K429L419-F423 WeakPolarHBondContact O-CD2 3.28Å; L419-F423 VanDerWaalsContact O-CE2 3.3Å; L419-F423 WeakPolarHBondContact O-CE2 3.27Å; M420-F423 PolarHBondContact O-N 3.44Å; K421-F423 PolarHBondContact O-N 3.2Å; K421-F423 VanDerWaalsContact O-N 3.15Å; F423-K429 VanDerWaalsContact O-CE 3.29Å; F423-K429 WeakPolarHBondContact O-CE 3.25Å
424G80.6Confident88.7Confident31 Ų3141.2 Ų41.232%0.3221%0.206SC..SBendtrans74.2177.1173.300000115.3
425K85.5Confident88.3Confident73 Ų7347.4 Ų47.432%0.31723%0.233SC..BIsolated β-bridgetrans-74.9151.4169.9-63.6179.6178.5-178.30110.9Y201 Q202 E427 Y428Y201-K425 WeakPolarHBondContact O-CA 3.33Å; Q202-K425 HydrophobicContact CB-CG 4.31Å; K425-E427 HydrophobicContact CB-CB 4.45Å; K425-E427 PolarHBondContact O-N 2.69Å; K425-Y428 HydrophobicContact CB-CD2 3.95Å; K425-Y428 HydrophobicContact CB-CE2 4.03Å; K425-Y428 HydrophobicContact CD-CE2 4.32Å; K425-Y428 HydrophobicContact CG-CE2 4.22Å; K425-Y428 PolarHBondContact O-N 3.15Å; K425-Y428 VanDerWaalsContact O-N 3.08Å
426T86.5Confident87.7Confident1 Ų148.3 Ų48.31%0.00624%0.238CC..Hα-helixtrans-55.3-33174.7-54.30000112.4Y201 A300 Y301 Y428 K429 I430Y201-T426 PolarHBondContact O-N 3.42Å; Y201-T426 PolarHBondContact O-OG1 3.05Å; Y201-T426 VanDerWaalsContact O-OG1 3.12Å; A300-T426 HydrophobicContact CB-CG2 3.98Å; Y301-T426 HydrophobicContact CE2-CG2 4.15Å; T426-Y428 PolarHBondContact O-N 3.06Å; T426-K429 WeakPolarHBondContact O-CA 3.05Å; T426-K429 WeakPolarHBondContact O-CB 2.99Å; T426-K429 PolarHBondContact O-N 3.46Å; T426-I430 HydrophobicContact CG2-CD1 4.4Å; T426-I430 WeakPolarHBondContact O-CG1 3.36Å; T426-I430 PolarHBondContact O-N 2.89Å
427E88Confident87.2Confident37 Ų3745.7 Ų45.717%0.17323%0.225CC..Hα-helixtrans-51.8-46.1173.4-154.8-169.614700113.5R199 H200 K425 K429 I430 Y431R199-E427 HydrophobicContact CB-CB 4.39Å; R199-E427 HydrophobicContact CB-CG 4.46Å; R199-E427 PolarHBondContact O-N 3.2Å; H200-E427 IonicContact CE1-OE2 3.75Å; H200-E427 IonicContact ND1-OE2 3.92Å; K425-E427 HydrophobicContact CB-CB 4.45Å; K425-E427 PolarHBondContact O-N 2.69Å; E427-K429 VanDerWaalsContact C-N 3.27Å; E427-K429 PolarHBondContact O-N 3.03Å; E427-I430 WeakPolarHBondContact O-CB 3.42Å; E427-I430 PolarHBondContact O-N 3.28Å; E427-Y431 HydrophobicContact CG-CD2 4.47Å; E427-Y431 HydrophobicContact CG-CE2 3.67Å; E427-Y431 VanDerWaalsContact O-CD2 3.23Å; E427-Y431 WeakPolarHBondContact O-CD2 3.44Å; E427-Y431 PolarHBondContact O-N 3.07Å; E427-Y431 WeakPolarHBondContact OE1-CE2 3.43Å; E427-Y431 PolarHBondContact OE1-OH 2.96Å
428Y89.9Confident86.7Confident135 Ų13549.4 Ų49.453%0.52924%0.243SC..Hα-helixtrans-67.3-30.3178-56.3-58.7000112.3K425 T426 Y431 T432K425-Y428 HydrophobicContact CB-CD2 3.95Å; K425-Y428 HydrophobicContact CB-CE2 4.03Å; K425-Y428 HydrophobicContact CD-CE2 4.32Å; K425-Y428 HydrophobicContact CG-CE2 4.22Å; K425-Y428 PolarHBondContact O-N 3.15Å; K425-Y428 VanDerWaalsContact O-N 3.08Å; T426-Y428 PolarHBondContact O-N 3.06Å; Y428-Y431 HydrophobicContact CD1-CD2 4.35Å; Y428-T432 PolarHBondContact O-N 3.45Å; Y428-T432 PolarHBondContact O-OG1 2.68Å
429K90.1Very high86Confident8 Ų852.2 Ų52.24%0.03526%0.258CS..Hα-helixtrans-71.9-39.7176.1-55.3177.1-172.2166.60110.8F292 D296 K421 F423 T426 E427 T432 V433F292-K429 HydrophobicContact CD2-CB 4.1Å; F292-K429 HydrophobicContact CE2-CB 3.59Å; D296-K429 HydrophobicContact CB-CD 4.44Å; D296-K429 WeakPolarHBondContact OD1-CD 3.41Å; D296-K429 WeakPolarHBondContact OD1-CE 3.3Å; D296-K429 IonicContact OD1-NZ 3.93Å; D296-K429 PolarHBondContact OD1-NZ 3.43Å; K421-K429 WeakPolarHBondContact O-CE 3.3Å; K421-K429 PolarHBondContact O-NZ 2.92Å; F423-K429 VanDerWaalsContact O-CE 3.29Å; F423-K429 WeakPolarHBondContact O-CE 3.25Å; T426-K429 WeakPolarHBondContact O-CA 3.05Å; T426-K429 WeakPolarHBondContact O-CB 2.99Å; T426-K429 PolarHBondContact O-N 3.46Å; E427-K429 VanDerWaalsContact C-N 3.27Å; E427-K429 PolarHBondContact O-N 3.03Å; K429-T432 PolarHBondContact O-N 2.86Å; K429-V433 WeakPolarHBondContact O-CG2 3.4Å; K429-V433 PolarHBondContact O-N 3.2Å
430I89.9Confident85.1Confident7 Ų748.5 Ų48.54%0.03624%0.24CC..Hα-helixtrans-57.7-49.9171-64.8168.2000110.3R199 F292 L353 M356 W357 T426 E427 T432 V433 G434R199-I430 HydrophobicContact CB-CD1 4.3Å; F292-I430 HydrophobicContact CZ-CG1 3.73Å; L353-I430 HydrophobicContact CD2-CG2 4.19Å; M356-I430 HydrophobicContact CB-CD1 4.44Å; W357-I430 HydrophobicContact CB-CG2 4.42Å; T426-I430 HydrophobicContact CG2-CD1 4.4Å; T426-I430 WeakPolarHBondContact O-CG1 3.36Å; T426-I430 PolarHBondContact O-N 2.89Å; E427-I430 WeakPolarHBondContact O-CB 3.42Å; E427-I430 PolarHBondContact O-N 3.28Å; I430-T432 VanDerWaalsContact C-N 3.3Å; I430-T432 PolarHBondContact O-N 3.47Å; I430-V433 PolarHBondContact O-N 3.06Å; I430-G434 PolarHBondContact O-N 2.83Å
431Y89.3Confident84.1Confident107 Ų10746.3 Ų46.342%0.4223%0.231SC..Hα-helixtrans-60.5-38.7175.6-61.4-46.6000112.3W357 E427 Y428 G434 F435W357-Y431 AromaticContact CD1-CE1 3.96Å; W357-Y431 AromaticContact NE1-CE1 3.63Å; W357-Y431 AromaticContact NE1-CZ 3.5Å; W357-Y431 PolarHBondContact NE1-OH 3.4Å; E427-Y431 HydrophobicContact CG-CD2 4.47Å; E427-Y431 HydrophobicContact CG-CE2 3.67Å; E427-Y431 VanDerWaalsContact O-CD2 3.23Å; E427-Y431 WeakPolarHBondContact O-CD2 3.44Å; E427-Y431 PolarHBondContact O-N 3.07Å; E427-Y431 WeakPolarHBondContact OE1-CE2 3.43Å; E427-Y431 PolarHBondContact OE1-OH 2.96Å; Y428-Y431 HydrophobicContact CD1-CD2 4.35Å; Y431-G434 PolarHBondContact O-N 2.77Å; Y431-F435 WeakPolarHBondContact O-CB 3.09Å; Y431-F435 PolarHBondContact O-N 2.84Å
432T87.4Confident83.2Confident51 Ų5151.9 Ų51.931%0.31326%0.261SS..Hα-helixtrans-66-46.3178.4-50.90000111.8M420 Y428 K429 I430 G434 F435 V436M420-T432 HydrophobicContact CE-CG2 3.89Å; Y428-T432 PolarHBondContact O-N 3.45Å; Y428-T432 PolarHBondContact O-OG1 2.68Å; K429-T432 PolarHBondContact O-N 2.86Å; I430-T432 VanDerWaalsContact C-N 3.3Å; I430-T432 PolarHBondContact O-N 3.47Å; T432-G434 VanDerWaalsContact C-N 3.33Å; T432-G434 PolarHBondContact O-N 3.2Å; T432-F435 PolarHBondContact O-N 3.03Å; T432-V436 HydrophobicContact CG2-CG2 4.42Å; T432-V436 WeakPolarHBondContact O-CB 3.31Å; T432-V436 VanDerWaalsContact O-CG2 3.3Å; T432-V436 WeakPolarHBondContact O-CG2 3.4Å; T432-V436 PolarHBondContact O-N 3.44Å
433V88.6Confident81.9Confident6 Ų653.7 Ų53.74%0.03627%0.27CS..Hα-helixtrans-63.7-40.3176.61770000110.9I288 N289 F292 L353 W376 K429 I430 L437I288-V433 HydrophobicContact CG2-CG2 4.09Å; N289-V433 WeakPolarHBondContact OD1-CG1 3.01Å; F292-V433 HydrophobicContact CB-CG2 4.14Å; F292-V433 HydrophobicContact CD1-CG2 4.21Å; F292-V433 HydrophobicContact CD2-CG2 4.12Å; F292-V433 HydrophobicContact CG-CG2 3.87Å; L353-V433 HydrophobicContact CD1-CG1 4.16Å; L353-V433 HydrophobicContact CD2-CB 4.31Å; L353-V433 HydrophobicContact CD2-CG1 4.08Å; W376-V433 HydrophobicContact CH2-CG1 4.42Å; K429-V433 WeakPolarHBondContact O-CG2 3.4Å; K429-V433 PolarHBondContact O-N 3.2Å; I430-V433 PolarHBondContact O-N 3.06Å; V433-L437 WeakPolarHBondContact O-CB 3.41Å; V433-L437 PolarHBondContact O-N 2.93Å
434G87.5Confident80.4Confident18 Ų1848.3 Ų48.319%0.18625%0.252CS..Hα-helixtrans-63.4-44.1175.100000113.4I430 Y431 T432 L437 I438I430-G434 PolarHBondContact O-N 2.83Å; Y431-G434 PolarHBondContact O-N 2.77Å; T432-G434 VanDerWaalsContact C-N 3.33Å; T432-G434 PolarHBondContact O-N 3.2Å; G434-L437 WeakPolarHBondContact O-CB 3.2Å; G434-L437 PolarHBondContact O-N 3.06Å; G434-I438 WeakPolarHBondContact O-CG1 3.38Å; G434-I438 PolarHBondContact O-N 3.45Å; G434-I438 VanDerWaalsContact O-N 3.13Å
435F85.8Confident79.2Confident143 Ų14347.6 Ų47.663%0.62724%0.242SC*.Hα-helixtrans-63.8-45.7176.7-179.2-95000111.8Y431 T432 L437 I438 D439Y431-F435 WeakPolarHBondContact O-CB 3.09Å; Y431-F435 PolarHBondContact O-N 2.84Å; T432-F435 PolarHBondContact O-N 3.03Å; F435-L437 VanDerWaalsContact C-N 3.28Å; F435-L437 PolarHBondContact O-N 2.96Å; F435-I438 PolarHBondContact O-N 3.32Å; F435-I438 VanDerWaalsContact O-N 3.17Å; F435-D439 WeakPolarHBondContact O-CB 3.36Å; F435-D439 PolarHBondContact O-N 2.91Å
436V83.7Confident77.5Confident29 Ų2945.8 Ų45.818%0.17624%0.235CC..Hα-helixtrans-68.5-27.2179176.80000111.8C285 T432 A440C285-V436 HydrophobicContact CB-CG1 3.65Å; T432-V436 HydrophobicContact CG2-CG2 4.42Å; T432-V436 WeakPolarHBondContact O-CB 3.31Å; T432-V436 VanDerWaalsContact O-CG2 3.3Å; T432-V436 WeakPolarHBondContact O-CG2 3.4Å; T432-V436 PolarHBondContact O-N 3.44Å; V436-A440 WeakPolarHBondContact O-CB 3.44Å; V436-A440 PolarHBondContact O-N 3.01Å
437L83.7Confident75.7Confident6 Ų649.7 Ų49.73%0.03126%0.259CS..Hα-helixtrans-66.1-43.3169.8-170.977.7000112.1F346 Q349 A350 L353 W383 V433 G434 F435 A440 S441F346-L437 HydrophobicContact CD2-CD2 3.95Å; F346-L437 HydrophobicContact CD2-CG 3.89Å; F346-L437 HydrophobicContact CE2-CD2 3.99Å; F346-L437 HydrophobicContact CE2-CG 3.96Å; Q349-L437 HydrophobicContact CB-CD1 4.19Å; Q349-L437 HydrophobicContact CB-CD2 3.94Å; Q349-L437 HydrophobicContact CG-CD1 3.74Å; Q349-L437 HydrophobicContact CG-CD2 3.8Å; Q349-L437 HydrophobicContact CG-CG 4.41Å; A350-L437 HydrophobicContact CB-CD2 4.49Å; L353-L437 HydrophobicContact CD1-CD2 4.49Å; W383-L437 HydrophobicContact CZ2-CD1 3.89Å; V433-L437 WeakPolarHBondContact O-CB 3.41Å; V433-L437 PolarHBondContact O-N 2.93Å; G434-L437 WeakPolarHBondContact O-CB 3.2Å; G434-L437 PolarHBondContact O-N 3.06Å; F435-L437 VanDerWaalsContact C-N 3.28Å; F435-L437 PolarHBondContact O-N 2.96Å; L437-A440 PolarHBondContact O-N 3.38Å; L437-S441 PolarHBondContact O-N 3.02Å; L437-S441 VanDerWaalsContact O-N 3.07Å
438I82.2Confident74.1Confident82 Ų8252.7 Ų52.742%0.42127%0.271SS..Hα-helixtrans-69-45.4178.7-65.6163.5000110.5F346 G434 F435 A440 S441 D442F346-I438 HydrophobicContact CE2-CG1 4.41Å; F346-I438 HydrophobicContact CZ-CG1 4.32Å; G434-I438 WeakPolarHBondContact O-CG1 3.38Å; G434-I438 PolarHBondContact O-N 3.45Å; G434-I438 VanDerWaalsContact O-N 3.13Å; F435-I438 PolarHBondContact O-N 3.32Å; F435-I438 VanDerWaalsContact O-N 3.17Å; I438-A440 PolarHBondContact O-N 3.06Å; I438-S441 PolarHBondContact O-N 2.92Å; I438-S441 VanDerWaalsContact O-N 3.08Å; I438-S441 PolarHBondContact O-OG 3.41Å; I438-D442 WeakPolarHBondContact O-CB 3.29Å; I438-D442 PolarHBondContact O-N 3.42Å
439D77.4Confident72.4Confident59 Ų5948.3 Ų48.332%0.31626%0.257SS..Hα-helixtrans-57.8-37.4172.8178.971.3000111.3F435 N443F435-D439 WeakPolarHBondContact O-CB 3.36Å; F435-D439 PolarHBondContact O-N 2.91Å; D439-N443 WeakPolarHBondContact O-CB 3.42Å; D439-N443 PolarHBondContact O-N 3.17Å; D439-N443 PolarHBondContact O-ND2 2.92Å; D439-N443 PolarHBondContact OD1-ND2 3.36Å; D439-N443 PolarHBondContact OD2-ND2 2.93Å
440A71.2Confident70.4Confident13 Ų1354.8 Ų54.811%0.10729%0.285CS..Hα-helixtrans-72.5-24.1175.600000114.7L282 C285 V436 L437 I438L282-A440 HydrophobicContact CB-CB 4.46Å; L282-A440 HydrophobicContact CD1-CB 3.99Å; C285-A440 HydrophobicContact CB-CB 4.39Å; V436-A440 WeakPolarHBondContact O-CB 3.44Å; V436-A440 PolarHBondContact O-N 3.01Å; L437-A440 PolarHBondContact O-N 3.38Å; I438-A440 PolarHBondContact O-N 3.06Å
441S69.2Low68.7Low15 Ų1559.4 Ų59.411%0.10531%0.307CS..Hα-helixtrans-82.1-39.3170.756.40000112.6F346 L437 I438F346-S441 WeakPolarHBondContact CE2-OG 3.33Å; L437-S441 PolarHBondContact O-N 3.02Å; L437-S441 VanDerWaalsContact O-N 3.07Å; I438-S441 PolarHBondContact O-N 2.92Å; I438-S441 VanDerWaalsContact O-N 3.08Å; I438-S441 PolarHBondContact O-OG 3.41Å
442D65.4Low67.1Low119 Ų11957.2 Ų57.264%0.63630%0.302SS*.Hα-helixtrans-81.6-25.4-174.3-71.93.5000112.7I438 G444I438-D442 WeakPolarHBondContact O-CB 3.29Å; I438-D442 PolarHBondContact O-N 3.42Å; D442-G444 PolarHBondContact O-N 3.23Å
443N55.5Low65.4Low53 Ų5359.4 Ų59.428%0.28331%0.307SS..SBendtrans-6774.9176.5-95.9-58.9000113D439 V445D439-N443 WeakPolarHBondContact O-CB 3.42Å; D439-N443 PolarHBondContact O-N 3.17Å; D439-N443 PolarHBondContact O-ND2 2.92Å; D439-N443 PolarHBondContact OD1-ND2 3.36Å; D439-N443 PolarHBondContact OD2-ND2 2.93Å; N443-V445 WeakPolarHBondContact O-CG2 3.36Å; N443-V445 PolarHBondContact O-N 3.4Å
444G51.2Low63.3Low21 Ų2161.1 Ų61.122%0.21632%0.323CS..SBendtrans50.415.6140.700000118.8R278 D442 K448R278-G444 PolarHBondContact NH1-O 3.38Å; D442-G444 PolarHBondContact O-N 3.23Å; G444-K448 VanDerWaalsContact O-CB 3.25Å; G444-K448 WeakPolarHBondContact O-CB 3.4Å; G444-K448 VanDerWaalsContact O-CG 3.24Å; G444-K448 WeakPolarHBondContact O-CG 3.37Å
445V54.5Low61.5Low17 Ų1762.4 Ų62.410%0.10333%0.331CS..SBendtrans-111.5-55.7-179.4172.80000107.7R278 L279 M390 N443 V447 K448 L449R278-V445 HydrophobicContact CB-CG2 3.67Å; L279-V445 HydrophobicContact CD2-CB 4.44Å; L279-V445 HydrophobicContact CD2-CG1 3.68Å; L279-V445 HydrophobicContact CD2-CG2 3.94Å; L279-V445 HydrophobicContact CG-CG2 4.23Å; M390-V445 HydrophobicContact CE-CG1 3.42Å; M390-V445 VanDerWaalsContact CE-CG1 3.42Å; N443-V445 WeakPolarHBondContact O-CG2 3.36Å; N443-V445 PolarHBondContact O-N 3.4Å; V445-V447 PolarHBondContact O-N 3.14Å; V445-K448 PolarHBondContact O-N 3.33Å; V445-L449 HydrophobicContact CG1-CD2 4.41Å; V445-L449 WeakPolarHBondContact O-CA 3.45Å; V445-L449 WeakPolarHBondContact O-CB 3.37Å; V445-L449 PolarHBondContact O-N 3.03Å
446L50Low59.9Low34 Ų3461.2 Ų61.218%0.17833%0.328CS..THydrogen-bonded Turntrans-51.7-45.8172.1-95.6151000111.7M339 L342 F450M339-L446 HydrophobicContact CE-CD2 4.01Å; M339-L446 VanDerWaalsContact CE-O 3.28Å; M339-L446 WeakPolarHBondContact CE-O 3.25Å; M339-L446 HydrophobicContact SD-CD2 3.8Å; L342-L446 HydrophobicContact CB-CD2 4.31Å; L342-L446 HydrophobicContact CD1-CD1 4.5Å; L342-L446 HydrophobicContact CD1-CD2 3.8Å; L342-L446 HydrophobicContact CD1-CG 4.13Å; L446-F450 WeakPolarHBondContact O-CB 3.47Å; L446-F450 PolarHBondContact O-N 3.46Å
447V48.6Very low57.9Low84 Ų8463.3 Ų63.351%0.50934%0.343SS..THydrogen-bonded Turntrans-70.3-59.3177-177.30000111.7V445 L449 F450 E451V445-V447 PolarHBondContact O-N 3.14Å; V447-L449 VanDerWaalsContact C-N 3.29Å; V447-L449 PolarHBondContact O-N 3.12Å; V447-F450 CarbonylContact O-C 3.59Å; V447-F450 WeakPolarHBondContact O-CA 3.35Å; V447-F450 VanDerWaalsContact O-CB 3.23Å; V447-F450 WeakPolarHBondContact O-CB 3.38Å; V447-F450 PolarHBondContact O-N 2.93Å; V447-E451 HydrophobicContact CG1-CG 4.45Å; V447-E451 PolarHBondContact O-N 3.04Å
448K56.1Low55.8Low99 Ų9968.4 Ų68.443%0.4337%0.369SS..Hα-helixtrans-68.9-23.9-174.4-60.4-160.4160.4-173.20114.2G444 V445 F450 E451 D452G444-K448 VanDerWaalsContact O-CB 3.25Å; G444-K448 WeakPolarHBondContact O-CB 3.4Å; G444-K448 VanDerWaalsContact O-CG 3.24Å; G444-K448 WeakPolarHBondContact O-CG 3.37Å; V445-K448 PolarHBondContact O-N 3.33Å; K448-F450 VanDerWaalsContact C-N 3.27Å; K448-E451 WeakPolarHBondContact CG-OE2 3.24Å; K448-E451 PolarHBondContact O-N 3.01Å; K448-D452 WeakPolarHBondContact O-CB 3.43Å; K448-D452 PolarHBondContact O-N 2.95Å
449L53.2Low54.2Low44 Ų4470.1 Ų70.123%0.2338%0.376CS..Hα-helixtrans-81.6-10.3173.1-162.465.2000112R338 V445 V447 K453R338-L449 VanDerWaalsContact CZ-CD2 3.4Å; R338-L449 VanDerWaalsContact NH2-CD2 3.29Å; V445-L449 HydrophobicContact CG1-CD2 4.41Å; V445-L449 WeakPolarHBondContact O-CA 3.45Å; V445-L449 WeakPolarHBondContact O-CB 3.37Å; V445-L449 PolarHBondContact O-N 3.03Å; V447-L449 VanDerWaalsContact C-N 3.29Å; V447-L449 PolarHBondContact O-N 3.12Å; L449-K453 WeakPolarHBondContact O-CB 3.43Å
450F49.3Very low52.6Low143 Ų14373 Ų7363%0.62739%0.387SS*.Hα-helixtrans-86.1-42163.2-166.6-85.6000110.3M339 L446 V447 K448 K453 A454M339-F450 HydrophobicContact CE-CB 4.29Å; L446-F450 WeakPolarHBondContact O-CB 3.47Å; L446-F450 PolarHBondContact O-N 3.46Å; V447-F450 CarbonylContact O-C 3.59Å; V447-F450 WeakPolarHBondContact O-CA 3.35Å; V447-F450 VanDerWaalsContact O-CB 3.23Å; V447-F450 WeakPolarHBondContact O-CB 3.38Å; V447-F450 PolarHBondContact O-N 2.93Å; K448-F450 VanDerWaalsContact C-N 3.27Å; F450-K453 PolarHBondContact O-N 3.19Å; F450-A454 VanDerWaalsContact O-CB 3.27Å; F450-A454 WeakPolarHBondContact O-CB 3.5Å; F450-A454 PolarHBondContact O-N 3.42Å
451E53.4Low50.9Low104 Ų10477.8 Ų77.849%0.48641%0.41SS..Hα-helixtrans-61.1-51.3172-64174.715700112V447 K448 K453 A454 A455V447-E451 HydrophobicContact CG1-CG 4.45Å; V447-E451 PolarHBondContact O-N 3.04Å; K448-E451 WeakPolarHBondContact CG-OE2 3.24Å; K448-E451 PolarHBondContact O-N 3.01Å; E451-K453 VanDerWaalsContact C-N 3.31Å; E451-K453 PolarHBondContact O-N 2.88Å; E451-A454 CarbonylContact O-C 3.59Å; E451-A454 PolarHBondContact O-N 2.8Å; E451-A454 VanDerWaalsContact O-N 3.13Å; E451-A455 WeakPolarHBondContact O-CB 3.25Å; E451-A455 PolarHBondContact O-N 3.19Å
452D55.9Low49.6Very low62 Ų6283.5 Ų83.533%0.33243%0.433SS..Hα-helixtrans-59.3-39.9178.1-75.2-27.6000110.9K448 Q456K448-D452 WeakPolarHBondContact O-CB 3.43Å; K448-D452 PolarHBondContact O-N 2.95Å; D452-Q456 WeakPolarHBondContact O-CB 3.42Å; D452-Q456 WeakPolarHBondContact O-CG 3.24Å; D452-Q456 PolarHBondContact O-N 2.98Å
453K52.3Low48.7Very low96 Ų9683.7 Ų83.742%0.41743%0.43SS..Hα-helixtrans-73.7-34174.7-81.2-160171-170.60113.2E393 L449 F450 E451 A455 C457E393-K453 IonicContact OE2-NZ 2.79Å; L449-K453 WeakPolarHBondContact O-CB 3.43Å; F450-K453 PolarHBondContact O-N 3.19Å; E451-K453 VanDerWaalsContact C-N 3.31Å; E451-K453 PolarHBondContact O-N 2.88Å; K453-A455 VanDerWaalsContact C-N 3.34Å; K453-C457 WeakPolarHBondContact O-CB 3.35Å; K453-C457 PolarHBondContact O-N 3.5Å; K453-C457 PolarHBondContact O-SG 2.64Å; K453-C457 VanDerWaalsContact O-SG 3.36Å
454A44.3Very low48.1Very low43 Ų4385.7 Ų85.736%0.35544%0.44SS..Hα-helixtrans-65.8-39.9172.300000110.9F450 E451 L458F450-A454 VanDerWaalsContact O-CB 3.27Å; F450-A454 WeakPolarHBondContact O-CB 3.5Å; F450-A454 PolarHBondContact O-N 3.42Å; E451-A454 CarbonylContact O-C 3.59Å; E451-A454 PolarHBondContact O-N 2.8Å; E451-A454 VanDerWaalsContact O-N 3.13Å; A454-L458 WeakPolarHBondContact O-CB 3.36Å; A454-L458 WeakPolarHBondContact O-CD1 3.18Å; A454-L458 VanDerWaalsContact O-CG 3.24Å; A454-L458 WeakPolarHBondContact O-CG 3.35Å; A454-L458 PolarHBondContact O-N 3.4Å
455A49Very low47.6Very low45 Ų4586.5 Ų86.537%0.37245%0.449SS..Hα-helixtrans-66.6-44.4174.800000112.2E451 K453 L458 Q459E451-A455 WeakPolarHBondContact O-CB 3.25Å; E451-A455 PolarHBondContact O-N 3.19Å; K453-A455 VanDerWaalsContact C-N 3.34Å; A455-L458 CarbonylContact O-C 3.48Å; A455-L458 WeakPolarHBondContact O-CB 3.23Å; A455-L458 PolarHBondContact O-N 3.18Å; A455-L458 VanDerWaalsContact O-N 3.15Å; A455-Q459 PolarHBondContact O-N 3.38Å
456Q52.6Low47Very low118 Ų11891 Ų9155%0.55147%0.469SS*.Hα-helixtrans-62.1-45.1173.8-78.1-177.7-32.400111.9D452 L458 Q459 Q460D452-Q456 WeakPolarHBondContact O-CB 3.42Å; D452-Q456 WeakPolarHBondContact O-CG 3.24Å; D452-Q456 PolarHBondContact O-N 2.98Å; Q456-L458 VanDerWaalsContact C-N 3.29Å; Q456-L458 PolarHBondContact O-N 2.88Å; Q456-Q459 PolarHBondContact O-N 3.41Å; Q456-Q460 WeakPolarHBondContact O-CB 3.34Å; Q456-Q460 PolarHBondContact O-N 2.94Å
457C41.4Very low46.5Very low73 Ų7394 Ų9449%0.49349%0.485SS..Hα-helixtrans-59.3-39.9171.9-74.90000111.8K453 I461K453-C457 WeakPolarHBondContact O-CB 3.35Å; K453-C457 PolarHBondContact O-N 3.5Å; K453-C457 PolarHBondContact O-SG 2.64Å; K453-C457 VanDerWaalsContact O-SG 3.36Å; C457-I461 WeakPolarHBondContact O-CB 3.43Å; C457-I461 VanDerWaalsContact O-CD1 3.3Å; C457-I461 WeakPolarHBondContact O-CD1 3.43Å; C457-I461 WeakPolarHBondContact O-CG1 3.37Å; C457-I461 PolarHBondContact O-N 3.34Å
458L39.7Very low46.1Very low112 Ų11294.9 Ų94.959%0.58648%0.482SS*.Hα-helixtrans-66.3-37.5176.8-78.8164.3000113.1A454 A455 Q456 K462A454-L458 WeakPolarHBondContact O-CB 3.36Å; A454-L458 WeakPolarHBondContact O-CD1 3.18Å; A454-L458 VanDerWaalsContact O-CG 3.24Å; A454-L458 WeakPolarHBondContact O-CG 3.35Å; A454-L458 PolarHBondContact O-N 3.4Å; A455-L458 CarbonylContact O-C 3.48Å; A455-L458 WeakPolarHBondContact O-CB 3.23Å; A455-L458 PolarHBondContact O-N 3.18Å; A455-L458 VanDerWaalsContact O-N 3.15Å; Q456-L458 VanDerWaalsContact C-N 3.29Å; Q456-L458 PolarHBondContact O-N 2.88Å; L458-K462 PolarHBondContact O-N 3.32Å
459Q48.8Very low45.4Very low118 Ų11895 Ų9555%0.55149%0.486SS*.Hα-helixtrans-69.1-47.7173.9-73-173.5-94.300111.5A455 Q456 I461 K462 E463A455-Q459 PolarHBondContact O-N 3.38Å; Q456-Q459 PolarHBondContact O-N 3.41Å; Q459-I461 VanDerWaalsContact C-N 3.31Å; Q459-I461 PolarHBondContact O-N 3.46Å; Q459-K462 WeakPolarHBondContact O-CA 3.35Å; Q459-K462 VanDerWaalsContact O-CB 3.28Å; Q459-K462 WeakPolarHBondContact O-CB 3.49Å; Q459-K462 PolarHBondContact O-N 3.26Å; Q459-E463 PolarHBondContact O-N 3.37Å
460Q43.3Very low44.9Very low121 Ų12198.2 Ų98.257%0.56550%0.504SS*.Hα-helixtrans-64.4-37.1-178.9-160.1166.114.200111.5Q456 K462 E463 D464Q456-Q460 WeakPolarHBondContact O-CB 3.34Å; Q456-Q460 PolarHBondContact O-N 2.94Å; Q460-K462 VanDerWaalsContact C-N 3.29Å; Q460-K462 PolarHBondContact O-N 2.81Å; Q460-E463 PolarHBondContact O-N 3.23Å; Q460-D464 WeakPolarHBondContact O-CB 3.48Å; Q460-D464 PolarHBondContact O-N 3.06Å
461I35.8Very low44.6Very low113 Ų11398.2 Ų98.258%0.57950%0.499SS*.Hα-helixtrans-65.8-27.6170.7-72166.7000112.5C457 Q459 G465C457-I461 WeakPolarHBondContact O-CB 3.43Å; C457-I461 VanDerWaalsContact O-CD1 3.3Å; C457-I461 WeakPolarHBondContact O-CD1 3.43Å; C457-I461 WeakPolarHBondContact O-CG1 3.37Å; C457-I461 PolarHBondContact O-N 3.34Å; Q459-I461 VanDerWaalsContact C-N 3.31Å; Q459-I461 PolarHBondContact O-N 3.46Å; I461-G465 PolarHBondContact O-N 2.68Å
462K42.2Very low44.2Very low135 Ų13598.2 Ų98.259%0.58750%0.503SS*.Hα-helixtrans-74.4-47.1173.9-168.4-165.5173.4-151.20110.9L458 Q459 Q460 G465 E466L458-K462 PolarHBondContact O-N 3.32Å; Q459-K462 WeakPolarHBondContact O-CA 3.35Å; Q459-K462 VanDerWaalsContact O-CB 3.28Å; Q459-K462 WeakPolarHBondContact O-CB 3.49Å; Q459-K462 PolarHBondContact O-N 3.26Å; Q460-K462 VanDerWaalsContact C-N 3.29Å; Q460-K462 PolarHBondContact O-N 2.81Å; K462-G465 WeakPolarHBondContact O-CA 3.29Å; K462-G465 PolarHBondContact O-N 2.94Å; K462-E466 WeakPolarHBondContact CE-OE1 3.34Å; K462-E466 IonicContact NZ-OE1 3.94Å; K462-E466 PolarHBondContact NZ-OE1 2.96Å; K462-E466 PolarHBondContact O-N 2.91Å; K462-E466 VanDerWaalsContact O-N 3.13Å
463E45.8Very low43.7Very low122 Ų122103.2 Ų103.257%0.5752%0.517SS*.Hα-helixtrans-62.9-47.1179.7-70.5165.1-175.300111.4Q459 Q460 G465 E466 L467Q459-E463 PolarHBondContact O-N 3.37Å; Q460-E463 PolarHBondContact O-N 3.23Å; E463-G465 PolarHBondContact O-N 3.3Å; E463-G465 VanDerWaalsContact O-N 3.17Å; E463-E466 PolarHBondContact O-N 2.76Å; E463-L467 WeakPolarHBondContact O-CB 2.91Å; E463-L467 PolarHBondContact O-N 2.79Å
464D43.5Very low43.2Very low95 Ų95101.1 Ų101.151%0.50852%0.517SS..Hα-helixtrans-60.9-22.4172-80.3-28.1000113.3Q460 K468Q460-D464 WeakPolarHBondContact O-CB 3.48Å; Q460-D464 PolarHBondContact O-N 3.06Å; D464-K468 PolarHBondContact O-N 2.69Å
465G40.1Very low43Very low39 Ų39104.6 Ų104.640%0.40253%0.528SS..Hα-helixtrans-75-49.5176.200000112.7I461 K462 E463 L467 K468 L469I461-G465 PolarHBondContact O-N 2.68Å; K462-G465 WeakPolarHBondContact O-CA 3.29Å; K462-G465 PolarHBondContact O-N 2.94Å; E463-G465 PolarHBondContact O-N 3.3Å; E463-G465 VanDerWaalsContact O-N 3.17Å; G465-L467 VanDerWaalsContact C-N 3.34Å; G465-K468 PolarHBondContact O-N 2.95Å; G465-L469 PolarHBondContact O-N 3.38Å
466E41.8Very low42.8Very low110 Ų110105.1 Ų105.151%0.51453%0.532SS..Hα-helixtrans-68.7-34.6176.8-67.8-179-154.300111.2K462 E463 K468 L469 L470K462-E466 WeakPolarHBondContact CE-OE1 3.34Å; K462-E466 IonicContact NZ-OE1 3.94Å; K462-E466 PolarHBondContact NZ-OE1 2.96Å; K462-E466 PolarHBondContact O-N 2.91Å; K462-E466 VanDerWaalsContact O-N 3.13Å; E463-E466 PolarHBondContact O-N 2.76Å; E466-K468 VanDerWaalsContact C-N 3.27Å; E466-K468 PolarHBondContact O-N 2.99Å; E466-L469 WeakPolarHBondContact O-CB 3.25Å; E466-L469 PolarHBondContact O-N 3.15Å; E466-L469 VanDerWaalsContact O-N 3.14Å; E466-L470 PolarHBondContact O-N 2.9Å; E466-L470 VanDerWaalsContact O-N 3.09Å
467L38.9Very low42.4Very low97 Ų97105 Ų10551%0.50854%0.535SS..Hα-helixtrans-64.9-28.1176.1-149.777.9000113.4E463 G465 R471E463-L467 WeakPolarHBondContact O-CB 2.91Å; E463-L467 PolarHBondContact O-N 2.79Å; G465-L467 VanDerWaalsContact C-N 3.34Å; L467-R471 WeakPolarHBondContact O-CB 3.49Å; L467-R471 PolarHBondContact O-N 2.98Å
468K41.5Very low42.3Very low103 Ų103107.5 Ų107.545%0.44854%0.542SS..Hα-helixtrans-73.5-43.2169.9-81.9-179.8174.9179.70112.4D464 G465 E466 L470 R471 D472D464-K468 PolarHBondContact O-N 2.69Å; G465-K468 PolarHBondContact O-N 2.95Å; E466-K468 VanDerWaalsContact C-N 3.27Å; E466-K468 PolarHBondContact O-N 2.99Å; K468-L470 PolarHBondContact O-N 3.48Å; K468-R471 WeakPolarHBondContact O-CB 3.46Å; K468-R471 PolarHBondContact O-N 3.38Å; K468-R471 VanDerWaalsContact O-N 3.07Å; K468-D472 PolarHBondContact O-N 3.36Å
469L41.1Very low42.3Very low101 Ų101110.2 Ų110.253%0.52955%0.552SS.*Hα-helixtrans-59-36.9178.8-162.482.1000112.1G465 E466 R473G465-L469 PolarHBondContact O-N 3.38Å; E466-L469 WeakPolarHBondContact O-CB 3.25Å; E466-L469 PolarHBondContact O-N 3.15Å; E466-L469 VanDerWaalsContact O-N 3.14Å; L469-R473 WeakPolarHBondContact O-CG 3.41Å; L469-R473 PolarHBondContact O-N 3.4Å
470L41.4Very low42Very low113 Ų113112.4 Ų112.459%0.59256%0.563SS**Hα-helixtrans-69.2-44.9172.9-72.6164.9000112.2E466 K468 R473 A474E466-L470 PolarHBondContact O-N 2.9Å; E466-L470 VanDerWaalsContact O-N 3.09Å; K468-L470 PolarHBondContact O-N 3.48Å; L470-R473 PolarHBondContact O-N 2.87Å; L470-A474 PolarHBondContact O-N 2.73Å; L470-A474 VanDerWaalsContact O-N 3.07Å
471R44.1Very low42Very low142 Ų142116.2 Ų116.254%0.53657%0.572SS.*Hα-helixtrans-61.5-44.7178.9-174.7179.6-58.5175.44.6112.7L467 K468 R473 A474 M475L467-R471 WeakPolarHBondContact O-CB 3.49Å; L467-R471 PolarHBondContact O-N 2.98Å; K468-R471 WeakPolarHBondContact O-CB 3.46Å; K468-R471 PolarHBondContact O-N 3.38Å; K468-R471 VanDerWaalsContact O-N 3.07Å; R471-R473 VanDerWaalsContact C-N 3.31Å; R471-R473 PolarHBondContact O-N 3.13Å; R471-A474 PolarHBondContact O-N 2.86Å; R471-M475 HydrophobicContact CG-CG 4.34Å; R471-M475 WeakPolarHBondContact O-CB 3.35Å; R471-M475 WeakPolarHBondContact O-CG 3.22Å; R471-M475 PolarHBondContact O-N 3.17Å
472D45.5Very low41.8Very low105 Ų105115 Ų11556%0.56159%0.587SS**Hα-helixtrans-72.1-28.6-175.4-63.2-20.1000111.4K468 A476K468-D472 PolarHBondContact O-N 3.36Å; D472-A476 PolarHBondContact O-N 3.35Å
473R45.4Very low41.5Very low166 Ų166110.6 Ų110.663%0.62658%0.58SS**Hα-helixtrans-67-49.3167.8-74.1176179.9174.80.9112L469 L470 R471 M475 A476 D477L469-R473 WeakPolarHBondContact O-CG 3.41Å; L469-R473 PolarHBondContact O-N 3.4Å; L470-R473 PolarHBondContact O-N 2.87Å; R471-R473 VanDerWaalsContact C-N 3.31Å; R471-R473 PolarHBondContact O-N 3.13Å; R473-M475 VanDerWaalsContact C-N 3.27Å; R473-M475 PolarHBondContact O-N 2.88Å; R473-A476 WeakPolarHBondContact O-CB 3.32Å; R473-A476 PolarHBondContact O-N 3.45Å; R473-A476 VanDerWaalsContact O-N 3.1Å; R473-D477 PolarHBondContact O-N 2.73Å
474A41.9Very low41.2Very low52 Ų52115.3 Ų115.343%0.4359%0.592SS.*Hα-helixtrans-61.5-35178.500000112.7L470 R471 A476 I478L470-A474 PolarHBondContact O-N 2.73Å; L470-A474 VanDerWaalsContact O-N 3.07Å; R471-A474 PolarHBondContact O-N 2.86Å; A474-A476 VanDerWaalsContact C-N 3.34Å; A474-I478 WeakPolarHBondContact O-CD1 3.43Å; A474-I478 VanDerWaalsContact O-CG1 3.27Å; A474-I478 WeakPolarHBondContact O-CG1 3.21Å; A474-I478 PolarHBondContact O-N 3.48Å
475M39.3Very low41.1Very low116 Ų116118.7 Ų118.757%0.57161%0.605SS**Hα-helixtrans-67.7-31.5175.6-70.1-86.6-72.300112.8R471 R473 Q479R471-M475 HydrophobicContact CG-CG 4.34Å; R471-M475 WeakPolarHBondContact O-CB 3.35Å; R471-M475 WeakPolarHBondContact O-CG 3.22Å; R471-M475 PolarHBondContact O-N 3.17Å; R473-M475 VanDerWaalsContact C-N 3.27Å; R473-M475 PolarHBondContact O-N 2.88Å; M475-Q479 WeakPolarHBondContact O-CB 3.44Å; M475-Q479 PolarHBondContact O-N 2.9Å
476A45.7Very low41.1Very low57 Ų57124 Ų12447%0.47162%0.619SS.*Hα-helixtrans-67.8-50177.300000111.8D472 R473 A474 I478 Q479 E480D472-A476 PolarHBondContact O-N 3.35Å; R473-A476 WeakPolarHBondContact O-CB 3.32Å; R473-A476 PolarHBondContact O-N 3.45Å; R473-A476 VanDerWaalsContact O-N 3.1Å; A474-A476 VanDerWaalsContact C-N 3.34Å; A476-I478 VanDerWaalsContact C-N 3.26Å; A476-I478 PolarHBondContact O-N 3.07Å; A476-Q479 PolarHBondContact O-N 3.28Å; A476-E480 PolarHBondContact O-N 3.17Å
477D42.5Very low40.7Very low115 Ų115122.2 Ų122.262%0.61561%0.613SS**Hα-helixtrans-59.3-36.8178.7-74.3-0.9000112.3R473R473-D477 PolarHBondContact O-N 2.73Å
478I39.7Very low40.8Very low125 Ų125125.5 Ų125.564%0.64162%0.623SS**Hα-helixtrans-70.6-31.9177.6-69168.8000111.8A474 A476 E480A474-I478 WeakPolarHBondContact O-CD1 3.43Å; A474-I478 VanDerWaalsContact O-CG1 3.27Å; A474-I478 WeakPolarHBondContact O-CG1 3.21Å; A474-I478 PolarHBondContact O-N 3.48Å; A476-I478 VanDerWaalsContact C-N 3.26Å; A476-I478 PolarHBondContact O-N 3.07Å; I478-E480 VanDerWaalsContact C-N 3.34Å
479Q39.6Very low40.8Very low170 Ų170125.9 Ų125.979%0.79463%0.63SS**Hα-helixtrans-78.8-18.1-177.5-167.1166.8-25.700113M475 A476M475-Q479 WeakPolarHBondContact O-CB 3.44Å; M475-Q479 PolarHBondContact O-N 2.9Å; A476-Q479 PolarHBondContact O-N 3.28Å
480E43.3Very low40.7Very low164 Ų164124.8 Ų124.877%0.76663%0.628SS**Hα-helixtrans-85.4-17.1176.9-148.8177.1-126.500113.3A476 I478A476-E480 PolarHBondContact O-N 3.17Å; I478-E480 VanDerWaalsContact C-N 3.34Å
481R42.1Very low40.6Very low201 Ų201123.6 Ų123.676%0.75863%0.625SS**  trans-121.975-171-60.4-173.5-174.5-168.73.8113G483R481-G483 PolarHBondContact O-N 3.12Å; R481-G483 VanDerWaalsContact O-N 3.17Å
482G33.7Very low40.3Very low88 Ų88120 Ų12091%0.90762%0.621SS**  trans-68.3106.6179.900000114
483G35.2Very low40.1Very low41 Ų41121.7 Ų121.742%0.42362%0.624SS.*  trans-154.571.717900000113.4R481 E485R481-G483 PolarHBondContact O-N 3.12Å; R481-G483 VanDerWaalsContact O-N 3.17Å; G483-E485 VanDerWaalsContact C-N 3.33Å; G483-E485 PolarHBondContact O-N 3.2Å
484R38.4Very low39.7Very low221 Ų221117.4 Ų117.483%0.83461%0.613SS**THydrogen-bonded Turntrans-74.1-17.4-171.4-149.7177.5-167.9-170.20.9114.7E533R484-E533 IonicContact NH2-OE1 3.25Å; R484-E533 PolarHBondContact NH2-OE1 3.27Å
485E43.1Very low39.5Very low166 Ų166117.1 Ų117.178%0.77662%0.615SS**THydrogen-bonded Turntrans-107.4-30.6-171.4-61.3-173.2154.100113.8G483 L487 F488G483-E485 VanDerWaalsContact C-N 3.33Å; G483-E485 PolarHBondContact O-N 3.2Å; E485-L487 PolarHBondContact O-N 3.41Å; E485-F488 PolarHBondContact O-N 3.46Å
486E38.8Very low39.5Very low150 Ų150117.4 Ų117.470%0.70162%0.617SS**Hα-helixtrans-62.7-42.5179.2-66.3-171.5117.800112.2F488 N489 V490E486-F488 PolarHBondContact O-N 3.09Å; E486-N489 PolarHBondContact O-N 3.44Å; E486-V490 WeakPolarHBondContact O-CG2 3.37Å; E486-V490 PolarHBondContact O-N 3.45Å
487L34.7Very low39.1Very low74 Ų74119.3 Ų119.339%0.38762%0.619SS.*Hα-helixtrans-57.2-34.2-179.4-161.575.7000112.5E485 V491E485-L487 PolarHBondContact O-N 3.41Å; L487-V491 WeakPolarHBondContact O-CG2 3.39Å; L487-V491 PolarHBondContact O-N 2.87Å
488F40.4Very low38.8Very low165 Ų165120.9 Ų120.972%0.72462%0.621SS**Hα-helixtrans-71.6-34.2179.4-154-87.3000112.1E485 E486 S492E485-F488 PolarHBondContact O-N 3.46Å; E486-F488 PolarHBondContact O-N 3.09Å; F488-S492 PolarHBondContact O-N 2.89Å
489N40.3Very low38.8Very low111 Ų111121.7 Ų121.759%0.59463%0.625SS**Hα-helixtrans-74-35.9175.1-102.3-38000112.6E486 K493E486-N489 PolarHBondContact O-N 3.44Å; N489-K493 PolarHBondContact O-N 2.82Å
490V39.9Very low38.9Very low78 Ų78121.7 Ų121.747%0.47363%0.627SS.*Hα-helixtrans-66.2-50.6178.9171.80000111.1E486 S492 K493 L494E486-V490 WeakPolarHBondContact O-CG2 3.37Å; E486-V490 PolarHBondContact O-N 3.45Å; V490-S492 VanDerWaalsContact C-N 3.27Å; V490-S492 PolarHBondContact O-N 2.79Å; V490-K493 PolarHBondContact O-N 3.1Å; V490-K493 VanDerWaalsContact O-N 3.09Å; V490-L494 HydrophobicContact CG1-CD1 3.67Å; V490-L494 VanDerWaalsContact O-CD1 3.29Å; V490-L494 WeakPolarHBondContact O-CD1 3.27Å; V490-L494 PolarHBondContact O-N 2.99Å; V490-L494 VanDerWaalsContact O-N 3.07Å
491V38.6Very low38.9Very low89 Ų89121.4 Ų121.454%0.53963%0.625SS.*Hα-helixtrans-59.2-38178.9172.70000112L487 K493 G495L487-V491 WeakPolarHBondContact O-CG2 3.39Å; L487-V491 PolarHBondContact O-N 2.87Å; V491-K493 PolarHBondContact O-N 3.25Å; V491-G495 PolarHBondContact O-N 3.35Å
492S39.1Very low38.6Very low65 Ų65119.4 Ų119.446%0.45562%0.624SS.*Hα-helixtrans-62.1-39.1176.1-173.80000113F488 V490F488-S492 PolarHBondContact O-N 2.89Å; V490-S492 VanDerWaalsContact C-N 3.27Å; V490-S492 PolarHBondContact O-N 2.79Å
493K41.3Very low38.7Very low141 Ų141124.1 Ų124.161%0.61362%0.623SS**Hα-helixtrans-76.9-45.3-179.7-77.8-178.4172.4179.90113.3N489 V490 V491 G495 M496 N497N489-K493 PolarHBondContact O-N 2.82Å; V490-K493 PolarHBondContact O-N 3.1Å; V490-K493 VanDerWaalsContact O-N 3.09Å; V491-K493 PolarHBondContact O-N 3.25Å; K493-G495 VanDerWaalsContact C-N 3.3Å; K493-G495 PolarHBondContact O-N 3.18Å; K493-M496 PolarHBondContact O-N 3.31Å; K493-N497 PolarHBondContact O-N 3.4Å
494L36.7Very low38.7Very low77 Ų77127.4 Ų127.440%0.40364%0.637SS.*Hα-helixtrans-61.5-40.7179.7-86.883.3000111.6V490 M496 F498V490-L494 HydrophobicContact CG1-CD1 3.67Å; V490-L494 VanDerWaalsContact O-CD1 3.29Å; V490-L494 WeakPolarHBondContact O-CD1 3.27Å; V490-L494 PolarHBondContact O-N 2.99Å; V490-L494 VanDerWaalsContact O-N 3.07Å; L494-M496 PolarHBondContact O-N 3.39Å; L494-F498 WeakPolarHBondContact O-CB 3.47Å; L494-F498 PolarHBondContact O-N 3.13Å
495G36.7Very low38.6Very low46 Ų46124.4 Ų124.447%0.47464%0.637SS.*Hα-helixtrans-64.6-19.9-177.500000115.7V491 K493 I499V491-G495 PolarHBondContact O-N 3.35Å; K493-G495 VanDerWaalsContact C-N 3.3Å; K493-G495 PolarHBondContact O-N 3.18Å; G495-I499 WeakPolarHBondContact O-CD1 3.27Å
496M39.9Very low38.1Very low122 Ų122123.6 Ų123.660%0.60164%0.638SS**Hα-helixtrans-100.9-41177-69.1-167.9-67.400113K493 L494 F498 I499K493-M496 PolarHBondContact O-N 3.31Å; L494-M496 PolarHBondContact O-N 3.39Å; M496-F498 PolarHBondContact O-N 3.36Å; M496-I499 PolarHBondContact O-N 3.4Å
497N36.8Very low38Very low97 Ų97124.1 Ų124.152%0.51965%0.646SS.*Hα-helixtrans-63.6-42.3-179-71.618.9000111.8K493 I499 M500 E501K493-N497 PolarHBondContact O-N 3.4Å; N497-I499 PolarHBondContact O-N 3.3Å; N497-M500 PolarHBondContact O-N 3.48Å; N497-E501 PolarHBondContact O-N 3.37Å
498F35.7Very low38.2Very low148 Ų148128.4 Ų128.465%0.64967%0.669SS**Hα-helixtrans-63.1-15.8-178.8-151.3-87.6000113.8L494 M496L494-F498 WeakPolarHBondContact O-CB 3.47Å; L494-F498 PolarHBondContact O-N 3.13Å; M496-F498 PolarHBondContact O-N 3.36Å
499I39.5Very low38Very low142 Ų142128 Ų12873%0.72868%0.675SS**Hα-helixtrans-93.5-16.8177.8-62.8179.1000111.9G495 M496 N497G495-I499 WeakPolarHBondContact O-CD1 3.27Å; M496-I499 PolarHBondContact O-N 3.4Å; N497-I499 PolarHBondContact O-N 3.3Å
500M42.3Very low38.2Very low169 Ų169126.6 Ų126.683%0.83367%0.667SS**Hα-helixtrans-104.5-16.6-177.8-59.5-167.585.400114.2N497N497-M500 PolarHBondContact O-N 3.48Å
501E43.4Very low38.7Very low159 Ų159128.5 Ų128.574%0.74368%0.681SS**SBendtrans-1013.4-166.8-155.9152.5-146.200114.9N497N497-E501 PolarHBondContact O-N 3.37Å
502Q35.9Very low39.1Very low158 Ų158129 Ų12974%0.73868%0.68SS**  trans-130.886.6172.4-70.5-166.8-12.400112.7
503Q35.1Very low39.3Very low188 Ų188130.9 Ų130.988%0.87969%0.685SS**  trans-103159.3154-97.7-164.2-38.900110
504P36.1Very low39.1Very low109 Ų109128.6 Ų128.671%0.70868%0.683SS**  trans-86.5158.1-147.833.5-38000115.2
505N36.2Very low39.2Very low159 Ų159126.8 Ų126.885%0.8568%0.677SS**  trans-141.9160147.8-86.1-52.1000108.3
506D33.1Very low39.3Very low148 Ų148131.9 Ų131.979%0.79168%0.682SS**  trans-78.6-179.7-170.1-58.9-76.5000114.5
507D35.4Very low39.2Very low161 Ų161129.7 Ų129.786%0.86167%0.672SS**  trans63.281.5172.3-61.3-24.8000117.8
508D39.6Very low39.2Very low165 Ų165130.6 Ų130.688%0.88267%0.673SS**  -168.3159.898.6-138.6-29.2000113.8D510D508-D510 PolarHBondContact O-N 3.04Å
509N37.3Very low39.5Very low157 Ų157128.1 Ų128.184%0.8467%0.666SS**  trans-95.774.5-179.7-88.5-77.2000113P511N509-P511 VanDerWaalsContact O-CD 3.26Å; N509-P511 WeakPolarHBondContact O-CD 3.47Å
510D44.6Very low39.5Very low80 Ų80126.9 Ų126.943%0.42866%0.657SS.*  trans-99.7101.5168.9-169.9-2.1000112.9D508 N512 L513D508-D510 PolarHBondContact O-N 3.04Å; D510-N512 PolarHBondContact O-N 3.48Å; D510-N512 VanDerWaalsContact O-N 3.13Å; D510-N512 WeakPolarHBondContact OD1-CB 3.39Å; D510-N512 PolarHBondContact OD1-N 3.03Å; D510-L513 WeakPolarHBondContact O-CB 3.23Å; D510-L513 PolarHBondContact O-N 2.93Å; D510-L513 VanDerWaalsContact O-N 3.11Å
511P50Low39.1Very low118 Ų118124.3 Ų124.377%0.76664%0.644SS**THydrogen-bonded Turntrans-68.7-5.2176.630.1-35.9000114.3N509N509-P511 VanDerWaalsContact O-CD 3.26Å; N509-P511 WeakPolarHBondContact O-CD 3.47Å
512N46.9Very low38.7Very low99 Ų99122 Ų12253%0.52964%0.637SS.*THydrogen-bonded Turntrans-92.70.3170.5-90.6-46.6000114.2D510 T514 S515 R516D510-N512 PolarHBondContact O-N 3.48Å; D510-N512 VanDerWaalsContact O-N 3.13Å; D510-N512 WeakPolarHBondContact OD1-CB 3.39Å; D510-N512 PolarHBondContact OD1-N 3.03Å; N512-T514 VanDerWaalsContact C-N 3.34Å; N512-T514 PolarHBondContact O-N 3.35Å; N512-S515 VanDerWaalsContact CA-OG 3.31Å; N512-S515 WeakPolarHBondContact CA-OG 3.48Å; N512-S515 PolarHBondContact O-N 3.27Å; N512-S515 PolarHBondContact O-OG 3.04Å; N512-S515 PolarHBondContact OD1-OG 2.92Å; N512-R516 WeakPolarHBondContact O-CB 3.37Å; N512-R516 WeakPolarHBondContact O-CG 3.48Å; N512-R516 PolarHBondContact O-N 2.98Å
513L42Very low38.9Very low105 Ų105120.2 Ų120.255%0.5563%0.628SS.*Hα-helixtrans-63.4-41177.2-170.167.4000111.6D510 R516 L517D510-L513 WeakPolarHBondContact O-CB 3.23Å; D510-L513 PolarHBondContact O-N 2.93Å; D510-L513 VanDerWaalsContact O-N 3.11Å; L513-R516 PolarHBondContact O-N 3.25Å; L513-L517 HydrophobicContact CD1-CD1 4.33Å; L513-L517 HydrophobicContact CG-CD1 4.41Å; L513-L517 PolarHBondContact O-N 2.82Å
514T37.6Very low38.9Very low94 Ų94116.6 Ų116.658%0.57761%0.611SS**Hα-helixtrans-70.3-34.2-179.9-36.40000112.8N512 Q518N512-T514 VanDerWaalsContact C-N 3.34Å; N512-T514 PolarHBondContact O-N 3.35Å; T514-Q518 WeakPolarHBondContact O-CB 3.39Å; T514-Q518 VanDerWaalsContact O-CG 3.27Å; T514-Q518 WeakPolarHBondContact O-CG 3.32Å; T514-Q518 PolarHBondContact O-N 3.08Å
515S38.2Very low38.8Very low39 Ų39116.4 Ų116.427%0.27360%0.603SS.*Hα-helixtrans-72.8-37.7175.251.90000111.4N512 Q518 I519N512-S515 VanDerWaalsContact CA-OG 3.31Å; N512-S515 WeakPolarHBondContact CA-OG 3.48Å; N512-S515 PolarHBondContact O-N 3.27Å; N512-S515 PolarHBondContact O-OG 3.04Å; N512-S515 PolarHBondContact OD1-OG 2.92Å; S515-Q518 PolarHBondContact O-N 3.38Å; S515-I519 WeakPolarHBondContact O-CD1 3.18Å; S515-I519 VanDerWaalsContact O-CG1 3.25Å; S515-I519 WeakPolarHBondContact O-CG1 3.3Å; S515-I519 PolarHBondContact O-N 3.03Å
516R39Very low39Very low153 Ų153116.9 Ų116.958%0.57760%0.601SS**Hα-helixtrans-61.2-51.7170.5-76.7177.6124.8168.3-4.2112.1N512 L513 Q518 I519 E520N512-R516 WeakPolarHBondContact O-CB 3.37Å; N512-R516 WeakPolarHBondContact O-CG 3.48Å; N512-R516 PolarHBondContact O-N 2.98Å; L513-R516 PolarHBondContact O-N 3.25Å; R516-Q518 VanDerWaalsContact C-N 3.26Å; R516-Q518 PolarHBondContact O-N 3.44Å; R516-I519 PolarHBondContact O-N 3.1Å; R516-E520 PolarHBondContact O-N 3.49Å
517L38.9Very low39.3Very low76 Ų76115.8 Ų115.840%0.39859%0.591SS.*Hα-helixtrans-57.6-38.3175.5-107.177.2000112.2L513 M521L513-L517 HydrophobicContact CD1-CD1 4.33Å; L513-L517 HydrophobicContact CG-CD1 4.41Å; L513-L517 PolarHBondContact O-N 2.82Å; L517-M521 WeakPolarHBondContact O-CB 3.48Å; L517-M521 PolarHBondContact O-N 3.35Å
518Q37.2Very low39.4Very low115 Ų115110.1 Ų110.154%0.53756%0.564SS.*Hα-helixtrans-68.2-35.2176.1-78.4177.7-0.500113T514 S515 R516 L522T514-Q518 WeakPolarHBondContact O-CB 3.39Å; T514-Q518 VanDerWaalsContact O-CG 3.27Å; T514-Q518 WeakPolarHBondContact O-CG 3.32Å; T514-Q518 PolarHBondContact O-N 3.08Å; S515-Q518 PolarHBondContact O-N 3.38Å; R516-Q518 VanDerWaalsContact C-N 3.26Å; R516-Q518 PolarHBondContact O-N 3.44Å; Q518-L522 VanDerWaalsContact O-CB 3.24Å; Q518-L522 WeakPolarHBondContact O-CB 3.4Å; Q518-L522 WeakPolarHBondContact O-CD1 3.18Å; Q518-L522 WeakPolarHBondContact O-CG 3.47Å; Q518-L522 PolarHBondContact O-N 3.41Å
519I41.2Very low39.2Very low97 Ų97105.7 Ų105.750%0.49755%0.546SS..Hα-helixtrans-72.4-47.6176.8-70.5164.2000110.6S515 R516 M521 L522 Q523S515-I519 WeakPolarHBondContact O-CD1 3.18Å; S515-I519 VanDerWaalsContact O-CG1 3.25Å; S515-I519 WeakPolarHBondContact O-CG1 3.3Å; S515-I519 PolarHBondContact O-N 3.03Å; R516-I519 PolarHBondContact O-N 3.1Å; I519-M521 PolarHBondContact O-N 2.75Å; I519-L522 WeakPolarHBondContact O-CB 3.17Å; I519-L522 PolarHBondContact O-N 3.37Å; I519-L522 VanDerWaalsContact O-N 3.16Å; I519-Q523 WeakPolarHBondContact O-CG 3.38Å; I519-Q523 PolarHBondContact O-N 3.11Å
520E38.6Very low39.1Very low116 Ų116104.9 Ų104.954%0.54254%0.541SS..Hα-helixtrans-64.5-40.9177.8-69.9174.9172.800111.5R516 L522 Q523 H524R516-E520 PolarHBondContact O-N 3.49Å; E520-L522 VanDerWaalsContact C-N 3.34Å; E520-L522 PolarHBondContact O-N 2.98Å; E520-Q523 PolarHBondContact O-N 3.46Å; E520-H524 PolarHBondContact O-N 3.03Å
521M35.6Very low38.8Very low114 Ų114105.7 Ų105.756%0.56255%0.548SS*.Hα-helixtrans-67.8-31.7173.5-169.4-176.971.100112.3L517 I519 L525L517-M521 WeakPolarHBondContact O-CB 3.48Å; L517-M521 PolarHBondContact O-N 3.35Å; I519-M521 PolarHBondContact O-N 2.75Å; M521-L525 HydrophobicContact CE-CD1 4.44Å; M521-L525 HydrophobicContact CG-CD1 4.09Å; M521-L525 VanDerWaalsContact O-CB 3.27Å; M521-L525 WeakPolarHBondContact O-CB 3.4Å; M521-L525 WeakPolarHBondContact O-CD1 3.49Å; M521-L525 WeakPolarHBondContact O-CG 3.3Å; M521-L525 PolarHBondContact O-N 2.88Å
522L35Very low38.2Very low112 Ų112104.9 Ų104.959%0.58654%0.537SS*.Hα-helixtrans-67.7-42.9171.2-86165.9000111.6Q518 I519 E520 L525 E526Q518-L522 VanDerWaalsContact O-CB 3.24Å; Q518-L522 WeakPolarHBondContact O-CB 3.4Å; Q518-L522 WeakPolarHBondContact O-CD1 3.18Å; Q518-L522 WeakPolarHBondContact O-CG 3.47Å; Q518-L522 PolarHBondContact O-N 3.41Å; I519-L522 WeakPolarHBondContact O-CB 3.17Å; I519-L522 PolarHBondContact O-N 3.37Å; I519-L522 VanDerWaalsContact O-N 3.16Å; E520-L522 VanDerWaalsContact C-N 3.34Å; E520-L522 PolarHBondContact O-N 2.98Å; L522-L525 PolarHBondContact O-N 3.42Å; L522-L525 VanDerWaalsContact O-N 3.16Å; L522-E526 PolarHBondContact O-N 3.21Å
523Q38.6Very low37.8Very low119 Ų119106.3 Ų106.356%0.55654%0.541SS*.Hα-helixtrans-61.1-44.5176.3-70.6178.1-80.800111.4I519 E520 L525 E526I519-Q523 WeakPolarHBondContact O-CG 3.38Å; I519-Q523 PolarHBondContact O-N 3.11Å; E520-Q523 PolarHBondContact O-N 3.46Å; Q523-L525 PolarHBondContact O-N 2.99Å; Q523-E526 PolarHBondContact O-N 2.7Å
524H36.1Very low37.3Very low113 Ų113109.3 Ų109.352%0.52355%0.55SS..Hα-helixtrans-69-27.6173.4-100-28.7000114E520 E526 E527E520-H524 PolarHBondContact O-N 3.03Å; H524-E526 VanDerWaalsContact C-N 3.35Å; H524-E527 IonicContact CE1-OE2 3.53Å; H524-E527 IonicContact CG-OE2 3.85Å; H524-E527 IonicContact ND1-OE2 3.33Å; H524-E527 PolarHBondContact ND1-OE2 2.96Å
525L34.7Very low37.2Very low104 Ų104109.7 Ų109.755%0.54555%0.548SS..Hα-helixtrans-75.4-24.3174.8-79167.7000112.8M521 L522 Q523 E527 S528M521-L525 HydrophobicContact CE-CD1 4.44Å; M521-L525 HydrophobicContact CG-CD1 4.09Å; M521-L525 VanDerWaalsContact O-CB 3.27Å; M521-L525 WeakPolarHBondContact O-CB 3.4Å; M521-L525 WeakPolarHBondContact O-CD1 3.49Å; M521-L525 WeakPolarHBondContact O-CG 3.3Å; M521-L525 PolarHBondContact O-N 2.88Å; L522-L525 PolarHBondContact O-N 3.42Å; L522-L525 VanDerWaalsContact O-N 3.16Å; Q523-L525 PolarHBondContact O-N 2.99Å; L525-E527 PolarHBondContact O-N 3.12Å; L525-S528 WeakPolarHBondContact O-CB 3.44Å; L525-S528 PolarHBondContact O-N 2.83Å
526E39.9Very low37Very low170 Ų170113.8 Ų113.879%0.79456%0.56SS**Hα-helixtrans-69.6-20.1176.3-154.5159.5-149.700112.3L522 Q523 H524 S528L522-E526 PolarHBondContact O-N 3.21Å; Q523-E526 PolarHBondContact O-N 2.7Å; H524-E526 VanDerWaalsContact C-N 3.35Å; E526-S528 VanDerWaalsContact C-N 3.33Å; E526-S528 PolarHBondContact O-N 2.9Å
527E39.2Very low36.9Very low125 Ų125109.5 Ų109.558%0.58455%0.554SS**THydrogen-bonded Turntrans-81.9-2.3177.7-59.2178.7130.600114.2H524 L525 S529H524-E527 IonicContact CE1-OE2 3.53Å; H524-E527 IonicContact CG-OE2 3.85Å; H524-E527 IonicContact ND1-OE2 3.33Å; H524-E527 PolarHBondContact ND1-OE2 2.96Å; L525-E527 PolarHBondContact O-N 3.12Å; E527-S529 PolarHBondContact O-N 3.32Å
528S36.5Very low36.8Very low42 Ų42111 Ų11129%0.29456%0.562SS.*  trans-81.6100.9-171.3-176.50000114.6L525 E526 L530 V531L525-S528 WeakPolarHBondContact O-CB 3.44Å; L525-S528 PolarHBondContact O-N 2.83Å; E526-S528 VanDerWaalsContact C-N 3.33Å; E526-S528 PolarHBondContact O-N 2.9Å; S528-L530 VanDerWaalsContact C-N 3.28Å; S528-L530 PolarHBondContact O-N 3.43Å; S528-L530 VanDerWaalsContact O-N 3.14Å; S528-V531 PolarHBondContact O-N 2.94Å
529S36.7Very low36.7Very low72 Ų72109 Ų10950%0.50356%0.557SS.*THydrogen-bonded Turntrans-57.5-29.1-175.665.30000116E527 V531 N532E527-S529 PolarHBondContact O-N 3.32Å; S529-V531 PolarHBondContact O-N 3.18Å; S529-N532 PolarHBondContact O-N 3.14Å
530L35.2Very low36.4Very low140 Ų140109.9 Ų109.973%0.73356%0.559SS**Hα-helixtrans-66.2-23.4-173.1-164.571.6000113.4S528S528-L530 VanDerWaalsContact C-N 3.28Å; S528-L530 PolarHBondContact O-N 3.43Å; S528-L530 VanDerWaalsContact O-N 3.14Å
531V36.8Very low36.3Very low96 Ų96114.1 Ų114.158%0.58257%0.57SS**Hα-helixtrans-74.2-32.7179.4-177.10000111.4S528 S529 K534 L535S528-V531 PolarHBondContact O-N 2.94Å; S529-V531 PolarHBondContact O-N 3.18Å; V531-K534 PolarHBondContact O-N 2.95Å; V531-L535 PolarHBondContact O-N 3.37Å
532N38.8Very low36.2Very low101 Ų101114.9 Ų114.954%0.5457%0.572SS.*Hα-helixtrans-70.3-35.8-171.1-88.4-45000114.3S529 K534 L535 K536S529-N532 PolarHBondContact O-N 3.14Å; N532-K534 PolarHBondContact O-N 3.18Å; N532-L535 PolarHBondContact O-N 3.02Å; N532-K536 WeakPolarHBondContact O-CB 3.48Å; N532-K536 PolarHBondContact O-N 3.08Å
533E37.3Very low36.1Very low130 Ų130113.9 Ų113.961%0.60757%0.567SS**Hα-helixtrans-64.5-38.1178.6-91.5-168177.900112.7R484 K536 S537R484-E533 IonicContact NH2-OE1 3.25Å; R484-E533 PolarHBondContact NH2-OE1 3.27Å; E533-K536 PolarHBondContact O-N 3.03Å; E533-S537 PolarHBondContact O-N 3.39Å
534K33.2Very low35.9Very low168 Ų168112.4 Ų112.473%0.7357%0.569SS**Hα-helixtrans-65-42.1175.6-112.4173.5-177.8168.30111.5V531 N532 S537V531-K534 PolarHBondContact O-N 2.95Å; N532-K534 PolarHBondContact O-N 3.18Å; K534-S537 PolarHBondContact O-N 2.92Å; K534-S537 PolarHBondContact O-OG 3.31Å
535L34.5Very low35.8Very low102 Ų102110.7 Ų110.753%0.53456%0.564SS.*Hα-helixtrans-63.1-43.1176.5-156.774.2000111.4V531 N532 S537 I538 V539V531-L535 PolarHBondContact O-N 3.37Å; N532-L535 PolarHBondContact O-N 3.02Å; L535-S537 PolarHBondContact O-N 3.38Å; L535-I538 WeakPolarHBondContact O-CB 3.21Å; L535-I538 PolarHBondContact O-N 3.21Å; L535-I538 VanDerWaalsContact O-N 3.08Å; L535-V539 PolarHBondContact O-N 3.35Å; L535-V539 VanDerWaalsContact O-N 3.11Å
536K33.7Very low35.9Very low124 Ų124110.6 Ų110.654%0.53957%0.57SS.*Hα-helixtrans-55.9-45.5177.6-174.9175.1175.4179.40112.5N532 E533 I538 V539 E540N532-K536 WeakPolarHBondContact O-CB 3.48Å; N532-K536 PolarHBondContact O-N 3.08Å; E533-K536 PolarHBondContact O-N 3.03Å; K536-I538 PolarHBondContact O-N 3.32Å; K536-I538 VanDerWaalsContact O-N 3.16Å; K536-V539 PolarHBondContact O-N 2.92Å; K536-V539 VanDerWaalsContact O-N 3.12Å; K536-E540 WeakPolarHBondContact CE-OE1 3.45Å; K536-E540 HydrophobicContact CG-CG 4.39Å; K536-E540 WeakPolarHBondContact CG-OE1 3.47Å; K536-E540 WeakPolarHBondContact O-CG 3.43Å; K536-E540 PolarHBondContact O-N 3.44Å
537S37.8Very low35.7Very low64 Ų64106.3 Ų106.345%0.44856%0.559SS.*Hα-helixtrans-61.2-24.3177.976.60000114.7E533 K534 L535E533-S537 PolarHBondContact O-N 3.39Å; K534-S537 PolarHBondContact O-N 2.92Å; K534-S537 PolarHBondContact O-OG 3.31Å; L535-S537 PolarHBondContact O-N 3.38Å
538I35.6Very low35.5Very low108 Ų108104.3 Ų104.355%0.55455%0.548SS*.Hα-helixtrans-84.4-39.7177.2-62.1169000110L535 K536 R541 Q542L535-I538 WeakPolarHBondContact O-CB 3.21Å; L535-I538 PolarHBondContact O-N 3.21Å; L535-I538 VanDerWaalsContact O-N 3.08Å; K536-I538 PolarHBondContact O-N 3.32Å; K536-I538 VanDerWaalsContact O-N 3.16Å; I538-R541 PolarHBondContact O-N 3.32Å; I538-Q542 PolarHBondContact O-N 2.72Å
539V35.1Very low35.3Very low73 Ų73107.5 Ų107.544%0.44256%0.558SS.*Hα-helixtrans-67.7-41.7177.9173.80000112L535 K536 R541 Q542 L543L535-V539 PolarHBondContact O-N 3.35Å; L535-V539 VanDerWaalsContact O-N 3.11Å; K536-V539 PolarHBondContact O-N 2.92Å; K536-V539 VanDerWaalsContact O-N 3.12Å; V539-R541 VanDerWaalsContact C-N 3.26Å; V539-R541 PolarHBondContact O-N 3.11Å; V539-Q542 PolarHBondContact O-N 3Å; V539-L543 HydrophobicContact CG1-CD1 4.07Å; V539-L543 PolarHBondContact O-N 2.63Å; V539-L543 VanDerWaalsContact O-N 3.13Å
540E35.8Very low35.3Very low114 Ų114106.8 Ų106.853%0.53355%0.553SS.*Hα-helixtrans-61-34.9178-73.6172.6173.500112.2K536 Q542 L543K536-E540 WeakPolarHBondContact CE-OE1 3.45Å; K536-E540 HydrophobicContact CG-CG 4.39Å; K536-E540 WeakPolarHBondContact CG-OE1 3.47Å; K536-E540 WeakPolarHBondContact O-CG 3.43Å; K536-E540 PolarHBondContact O-N 3.44Å; E540-Q542 VanDerWaalsContact C-N 3.29Å; E540-Q542 PolarHBondContact O-N 3.39Å; E540-L543 PolarHBondContact O-N 2.94Å
541R35.4Very low35.2Very low205 Ų205104.8 Ų104.877%0.77454%0.543SS*.Hα-helixtrans-68.6-20.4172.2-90.5-179.1167.1168.1-2.1114.8I538 V539 S544I538-R541 PolarHBondContact O-N 3.32Å; V539-R541 VanDerWaalsContact C-N 3.26Å; V539-R541 PolarHBondContact O-N 3.11Å; R541-S544 PolarHBondContact O-OG 3.29Å
542Q35Very low35Very low130 Ų130103.3 Ų103.361%0.60753%0.531SS*.Hα-helixtrans-89.8-26.5176.1-65.1-67.4-74.700111.9I538 V539 E540 S544I538-Q542 PolarHBondContact O-N 2.72Å; V539-Q542 PolarHBondContact O-N 3Å; E540-Q542 VanDerWaalsContact C-N 3.29Å; E540-Q542 PolarHBondContact O-N 3.39Å; Q542-S544 VanDerWaalsContact C-N 3.28Å; Q542-S544 PolarHBondContact O-N 2.56Å
543L33Very low34.9Very low91 Ų91103.2 Ų103.248%0.47653%0.53SS..Hα-helixtrans-70.3-18.7179.1-109.375000114.5V539 E540 D545 F548V539-L543 HydrophobicContact CG1-CD1 4.07Å; V539-L543 PolarHBondContact O-N 2.63Å; V539-L543 VanDerWaalsContact O-N 3.13Å; E540-L543 PolarHBondContact O-N 2.94Å; L543-D545 VanDerWaalsContact C-N 3.29Å; L543-D545 PolarHBondContact O-N 2.79Å; L543-F548 HydrophobicContact CD1-CD1 4.35Å; L543-F548 HydrophobicContact CD1-CE1 3.76Å; L543-F548 HydrophobicContact CG-CD1 4.43Å; L543-F548 HydrophobicContact CG-CE1 4.26Å
544S32.7Very low34.9Very low88 Ų88103.6 Ų103.662%0.61553%0.529SS*.THydrogen-bonded Turntrans-78.1-6.5179.854.30000114.8R541 Q542R541-S544 PolarHBondContact O-OG 3.29Å; Q542-S544 VanDerWaalsContact C-N 3.28Å; Q542-S544 PolarHBondContact O-N 2.56Å
545D34.9Very low34.8Very low78 Ų7898.9 Ų98.942%0.41751%0.511SS..  trans-79.2124.4-178.7-166.5-53.7000111.6L543 S547 F548 Q549L543-D545 VanDerWaalsContact C-N 3.29Å; L543-D545 PolarHBondContact O-N 2.79Å; D545-S547 VanDerWaalsContact CG-OG 3.3Å; D545-S547 PolarHBondContact O-N 3.28Å; D545-S547 WeakPolarHBondContact OD1-CB 3.23Å; D545-S547 PolarHBondContact OD1-N 3.27Å; D545-S547 PolarHBondContact OD1-OG 3.38Å; D545-F548 HydrophobicContact CB-CB 4.32Å; D545-F548 VanDerWaalsContact O-CB 3.28Å; D545-F548 WeakPolarHBondContact O-CB 3.41Å; D545-F548 PolarHBondContact O-N 3.5Å; D545-Q549 PolarHBondContact O-N 3.29Å
546P37.1Very low34.8Very low101 Ų10199.4 Ų99.466%0.65651%0.513SS*.Hα-helixtrans-64.6-20.6-179.526.3-34.7000113.9F548 S550P546-F548 VanDerWaalsContact C-N 3.33Å; P546-S550 PolarHBondContact O-N 3.08Å
547S35.5Very low35Very low80 Ų80102.1 Ų102.156%0.55952%0.52SS*.Hα-helixtrans-67.7-34.8171.271.10000111.9D545 L551D545-S547 VanDerWaalsContact CG-OG 3.3Å; D545-S547 PolarHBondContact O-N 3.28Å; D545-S547 WeakPolarHBondContact OD1-CB 3.23Å; D545-S547 PolarHBondContact OD1-N 3.27Å; D545-S547 PolarHBondContact OD1-OG 3.38Å; S547-L551 PolarHBondContact O-N 3.31Å
548F35Very low34.7Very low84 Ų84106 Ų10637%0.36853%0.529SS..Hα-helixtrans-70.4-41178-157.2-104.6000111.3L543 D545 P546 S550 L551 I552L543-F548 HydrophobicContact CD1-CD1 4.35Å; L543-F548 HydrophobicContact CD1-CE1 3.76Å; L543-F548 HydrophobicContact CG-CD1 4.43Å; L543-F548 HydrophobicContact CG-CE1 4.26Å; D545-F548 HydrophobicContact CB-CB 4.32Å; D545-F548 VanDerWaalsContact O-CB 3.28Å; D545-F548 WeakPolarHBondContact O-CB 3.41Å; D545-F548 PolarHBondContact O-N 3.5Å; P546-F548 VanDerWaalsContact C-N 3.33Å; F548-S550 PolarHBondContact O-N 3.01Å; F548-L551 WeakPolarHBondContact O-CB 3.28Å; F548-L551 PolarHBondContact O-N 3.08Å; F548-L551 VanDerWaalsContact O-N 3.08Å; F548-I552 HydrophobicContact CD1-CD1 3.95Å; F548-I552 HydrophobicContact CE1-CD1 4.15Å; F548-I552 PolarHBondContact O-N 2.86Å
549Q32.3Very low34.5Very low108 Ų108105 Ų10551%0.50553%0.528SS..Hα-helixtrans-63.9-37.8176.3-62-1741.600112.6D545 L551 I552 I553D545-Q549 PolarHBondContact O-N 3.29Å; Q549-L551 PolarHBondContact O-N 2.9Å; Q549-I552 PolarHBondContact O-N 3.28Å; Q549-I553 PolarHBondContact O-N 3.42Å
550S36.5Very low34.3Very low57 Ų57105.7 Ų105.740%0.39954%0.542SS..Hα-helixtrans-61.7-30.4172.9-165.40000112.9P546 F548 K554P546-S550 PolarHBondContact O-N 3.08Å; F548-S550 PolarHBondContact O-N 3.01Å; S550-K554 WeakPolarHBondContact O-CD 3.47Å; S550-K554 WeakPolarHBondContact O-CG 3.37Å
551L33.8Very low34.4Very low99 Ų99107.8 Ų107.852%0.51855%0.551SS.*Hα-helixtrans-71.8-47.5178-148.783.2000111.2S547 F548 Q549 I553 K554 I555S547-L551 PolarHBondContact O-N 3.31Å; F548-L551 WeakPolarHBondContact O-CB 3.28Å; F548-L551 PolarHBondContact O-N 3.08Å; F548-L551 VanDerWaalsContact O-N 3.08Å; Q549-L551 PolarHBondContact O-N 2.9Å; L551-I553 PolarHBondContact O-N 3.27Å; L551-K554 PolarHBondContact O-N 3.05Å; L551-K554 VanDerWaalsContact O-N 3.09Å; L551-I555 HydrophobicContact CD2-CD1 4.25Å; L551-I555 HydrophobicContact CG-CD1 4.25Å; L551-I555 WeakPolarHBondContact O-CG1 3.46Å; L551-I555 PolarHBondContact O-N 3.23Å
552I31.9Very low34.2Very low65 Ų65102.3 Ų102.333%0.33354%0.544SS..Hα-helixtrans-56.2-47.2-178.5-67.7167.6000111.3F548 Q549 K554 I555 I556F548-I552 HydrophobicContact CD1-CD1 3.95Å; F548-I552 HydrophobicContact CE1-CD1 4.15Å; F548-I552 PolarHBondContact O-N 2.86Å; Q549-I552 PolarHBondContact O-N 3.28Å; I552-K554 VanDerWaalsContact C-N 3.26Å; I552-K554 PolarHBondContact O-N 2.74Å; I552-I555 PolarHBondContact O-N 2.95Å; I552-I555 VanDerWaalsContact O-N 3.13Å; I552-I556 HydrophobicContact CG2-CD1 3.93Å; I552-I556 WeakPolarHBondContact O-CG1 3.45Å; I552-I556 PolarHBondContact O-N 3.39Å; I552-I556 VanDerWaalsContact O-N 3.07Å
553I37.3Very low34Very low99 Ų99104.5 Ų104.551%0.50855%0.554SS.*Hα-helixtrans-63.1-31.7-179.5-64170.5000112Q549 L551 R557Q549-I553 PolarHBondContact O-N 3.42Å; L551-I553 PolarHBondContact O-N 3.27Å; I553-R557 PolarHBondContact O-N 2.93Å
554K36Very low34.1Very low137 Ų137105.8 Ų105.860%0.59657%0.567SS**Hα-helixtrans-77.9-30.2176.4-71.8169-178.91590112.8S550 L551 I552 K558S550-K554 WeakPolarHBondContact O-CD 3.47Å; S550-K554 WeakPolarHBondContact O-CG 3.37Å; L551-K554 PolarHBondContact O-N 3.05Å; L551-K554 VanDerWaalsContact O-N 3.09Å; I552-K554 VanDerWaalsContact C-N 3.26Å; I552-K554 PolarHBondContact O-N 2.74Å; K554-K558 PolarHBondContact O-N 2.97Å
555I32.8Very low34.2Very low69 Ų69107.3 Ų107.335%0.35457%0.568SS.*Hα-helixtrans-69.3-50.5175.8-68.8163.6000110L551 I552 R557 K558 V559L551-I555 HydrophobicContact CD2-CD1 4.25Å; L551-I555 HydrophobicContact CG-CD1 4.25Å; L551-I555 WeakPolarHBondContact O-CG1 3.46Å; L551-I555 PolarHBondContact O-N 3.23Å; I552-I555 PolarHBondContact O-N 2.95Å; I552-I555 VanDerWaalsContact O-N 3.13Å; I555-R557 VanDerWaalsContact C-N 3.25Å; I555-R557 PolarHBondContact O-N 3.06Å; I555-K558 PolarHBondContact O-N 3.4Å; I555-V559 HydrophobicContact CG2-CG2 4.25Å; I555-V559 PolarHBondContact O-N 3.15Å
556I33.9Very low34.5Very low113 Ų113109 Ų10958%0.57958%0.576SS**Hα-helixtrans-52.8-45177.5-66.2165.8000111I552 K558 V559 A560I552-I556 HydrophobicContact CG2-CD1 3.93Å; I552-I556 WeakPolarHBondContact O-CG1 3.45Å; I552-I556 PolarHBondContact O-N 3.39Å; I552-I556 VanDerWaalsContact O-N 3.07Å; I556-K558 PolarHBondContact O-N 3.15Å; I556-V559 PolarHBondContact O-N 3.08Å; I556-A560 PolarHBondContact O-N 2.84Å
557R36.8Very low34.6Very low181 Ų181111.5 Ų111.568%0.68358%0.58SS**Hα-helixtrans-68.5-17.2-179.1-159.4178.3-62.1179.6-0.5114.4I553 I555I553-R557 PolarHBondContact O-N 2.93Å; I555-R557 VanDerWaalsContact C-N 3.25Å; I555-R557 PolarHBondContact O-N 3.06Å
558K32.4Very low34.8Very low146 Ų146111.5 Ų111.564%0.63558%0.576SS**Hα-helixtrans-95-36.8174.6-90.4-168.5167.4-168.10113.4K554 I555 I556 A560 Q561K554-K558 PolarHBondContact O-N 2.97Å; I555-K558 PolarHBondContact O-N 3.4Å; I556-K558 PolarHBondContact O-N 3.15Å; K558-A560 PolarHBondContact O-N 3.39Å; K558-Q561 PolarHBondContact O-N 2.66Å
559V30.5Very low35Very low86 Ų86110.1 Ų110.152%0.52158%0.575SS.*Hα-helixtrans-60.1-37.5176.6173.90000110.7I555 I556 Q561 S562I555-V559 HydrophobicContact CG2-CG2 4.25Å; I555-V559 PolarHBondContact O-N 3.15Å; I556-V559 PolarHBondContact O-N 3.08Å; V559-Q561 PolarHBondContact O-N 2.97Å; V559-S562 PolarHBondContact O-N 3.36Å
560A32.6Very low35.3Very low89 Ų89111.7 Ų111.774%0.73658%0.58SS**THydrogen-bonded Turntrans-66.43.3173.100000115.4I556 K558I556-A560 PolarHBondContact O-N 2.84Å; K558-A560 PolarHBondContact O-N 3.39Å
561Q36.4Very low35.4Very low158 Ų158111.9 Ų111.974%0.73859%0.585SS**THydrogen-bonded Turntrans-122.73.7-179.2-62.3-170.3-43.500113.9K558 V559K558-Q561 PolarHBondContact O-N 2.66Å; V559-Q561 PolarHBondContact O-N 2.97Å
562S31.2Very low35.6Very low90 Ų90112.1 Ų112.163%0.62959%0.585SS**SBendtrans-127.214.4-172.367.40000115.7V559V559-S562 PolarHBondContact O-N 3.36Å
563Q32.1Very low35.7Very low175 Ų175114 Ų11482%0.81860%0.596SS**  trans-104.2100170.8-77.1-169.7-29.200110.9
564T33.8Very low35.9Very low119 Ų119115 Ų11573%0.7361%0.607SS**  trans-146.471.117156.50000110.5
565D36.1Very low35.9Very low120 Ų120112.3 Ų112.364%0.64261%0.61SS**  trans-86.5130.7168.5-80.6-48.9000110.7E567 T568 V569D565-E567 PolarHBondContact O-N 3.44Å; D565-T568 PolarHBondContact O-N 2.94Å; D565-T568 VanDerWaalsContact O-N 3.17Å; D565-V569 WeakPolarHBondContact O-CG2 3.26Å; D565-V569 PolarHBondContact O-N 3.2Å
566D40.5Very low35.8Very low112 Ų112112.4 Ų112.460%0.59962%0.617SS**THydrogen-bonded Turntrans-62.5-13.5-171.9-104.8-16000113.6R588D566-R588 IonicContact OD2-NH2 3.34Å
567E40.1Very low35.9Very low155 Ų155115 Ų11572%0.72463%0.626SS**THydrogen-bonded Turntrans-95.3-39.3174.8-59-152.8129.100113.1D565 V569 K570 A571D565-E567 PolarHBondContact O-N 3.44Å; E567-V569 VanDerWaalsContact C-N 3.26Å; E567-V569 PolarHBondContact O-N 2.99Å; E567-K570 WeakPolarHBondContact O-CB 3.48Å; E567-K570 PolarHBondContact O-N 3.49Å; E567-A571 PolarHBondContact O-N 3.38Å
568T38.8Very low35.8Very low79 Ų79113 Ų11349%0.48563%0.629SS.*Hα-helixtrans-64.1-36.9171.3-34.10000110.5D565 K570 A571 I572D565-T568 PolarHBondContact O-N 2.94Å; D565-T568 VanDerWaalsContact O-N 3.17Å; T568-K570 PolarHBondContact O-N 3.47Å; T568-K570 VanDerWaalsContact C-N 3.28Å; T568-A571 PolarHBondContact O-N 2.91Å; T568-I572 HydrophobicContact CG2-CD1 4.08Å; T568-I572 WeakPolarHBondContact O-CB 3.33Å; T568-I572 VanDerWaalsContact O-CG1 3.29Å; T568-I572 WeakPolarHBondContact O-CG1 3.39Å; T568-I572 PolarHBondContact O-N 3.34Å
569V38.6Very low35.6Very low55 Ų55115.4 Ų115.433%0.33364%0.64SS.*Hα-helixtrans-61.4-33.9172.2170.80000111.7D565 E567 N573D565-V569 WeakPolarHBondContact O-CG2 3.26Å; D565-V569 PolarHBondContact O-N 3.2Å; E567-V569 VanDerWaalsContact C-N 3.26Å; E567-V569 PolarHBondContact O-N 2.99Å; V569-N573 WeakPolarHBondContact CG1-ND2 3.29Å; V569-N573 WeakPolarHBondContact O-CB 3.23Å; V569-N573 PolarHBondContact O-N 3.01Å; V569-N573 PolarHBondContact O-ND2 3.35Å
570K38.5Very low35.6Very low142 Ų142117.3 Ų117.362%0.61765%0.654SS**Hα-helixtrans-68.2-48.2172-79.3174.6179.3171.40112.1E567 T568 I572 N573 T574E567-K570 WeakPolarHBondContact O-CB 3.48Å; E567-K570 PolarHBondContact O-N 3.49Å; T568-K570 PolarHBondContact O-N 3.47Å; T568-K570 VanDerWaalsContact C-N 3.28Å; K570-I572 VanDerWaalsContact C-N 3.27Å; K570-I572 PolarHBondContact O-N 2.86Å; K570-N573 PolarHBondContact O-N 3.42Å; K570-T574 VanDerWaalsContact O-OG1 3.12Å; K570-T574 PolarHBondContact O-OG1 3.29Å; K570-T574 PolarHBondContact O-N 3.39Å
571A39.9Very low35.5Very low60 Ų60116.2 Ų116.250%0.49665%0.652SS.*Hα-helixtrans-58.9-39.1179.300000112.3E567 T568 T574E567-A571 PolarHBondContact O-N 3.38Å; T568-A571 PolarHBondContact O-N 2.91Å; A571-T574 WeakPolarHBondContact CA-OG1 3.41Å; A571-T574 PolarHBondContact O-OG1 3.01Å; A571-T574 PolarHBondContact O-N 3.01Å
572I36.9Very low35Very low104 Ų104119 Ų11953%0.53366%0.662SS.*Hα-helixtrans-70.2-42.3175.9-67.6166.4000111.5T568 K570 T574 A575 S576T568-I572 HydrophobicContact CG2-CD1 4.08Å; T568-I572 WeakPolarHBondContact O-CB 3.33Å; T568-I572 VanDerWaalsContact O-CG1 3.29Å; T568-I572 WeakPolarHBondContact O-CG1 3.39Å; T568-I572 PolarHBondContact O-N 3.34Å; K570-I572 VanDerWaalsContact C-N 3.27Å; K570-I572 PolarHBondContact O-N 2.86Å; I572-T574 PolarHBondContact O-N 3.28Å; I572-A575 PolarHBondContact O-N 2.61Å; I572-S576 PolarHBondContact O-N 3.37Å
573N35.3Very low35Very low106 Ų106119.3 Ų119.357%0.56767%0.67SS**Hα-helixtrans-65-22.8176.4-81.5-57000113.6V569 K570 A575V569-N573 WeakPolarHBondContact CG1-ND2 3.29Å; V569-N573 WeakPolarHBondContact O-CB 3.23Å; V569-N573 PolarHBondContact O-N 3.01Å; V569-N573 PolarHBondContact O-ND2 3.35Å; K570-N573 PolarHBondContact O-N 3.42Å; N573-A575 VanDerWaalsContact C-N 3.35Å
574T40.4Very low35Very low119 Ų119116.7 Ų116.773%0.7367%0.668SS**THydrogen-bonded Turntrans-81.3-10.2170.339.10000114.3K570 A571 I572K570-T574 VanDerWaalsContact O-OG1 3.12Å; K570-T574 PolarHBondContact O-OG1 3.29Å; K570-T574 PolarHBondContact O-N 3.39Å; A571-T574 WeakPolarHBondContact CA-OG1 3.41Å; A571-T574 PolarHBondContact O-OG1 3.01Å; A571-T574 PolarHBondContact O-N 3.01Å; I572-T574 PolarHBondContact O-N 3.28Å
575A37.1Very low34.7Very low80 Ų80123.3 Ų123.366%0.66168%0.679SS**THydrogen-bonded Turntrans-111.7-6.1-177.300000114I572 N573 H577I572-A575 PolarHBondContact O-N 2.61Å; N573-A575 VanDerWaalsContact C-N 3.35Å; A575-H577 PolarHBondContact O-N 3.47Å
576S30.8Very low34.4Very low71 Ų71123.9 Ų123.950%0.49769%0.687SS.*  trans-96.837.6-171.668.80000114.2I572 D578I572-S576 PolarHBondContact O-N 3.37Å; S576-D578 PolarHBondContact O-N 2.85Å
577H34.1Very low33.8Very low168 Ų168128.4 Ų128.478%0.77870%0.701SS**  trans-83.9-4.1-165.7-135.6-64000115.5A575A575-H577 PolarHBondContact O-N 3.47Å
578D34.7Very low33.1Very low140 Ų140131.7 Ų131.775%0.74971%0.707SS**SBendtrans-117-5-165.9-70.3-56.4000116.9S576S576-D578 PolarHBondContact O-N 2.85Å
579F29.2Very low32.6Very low196 Ų196137.4 Ų137.486%0.8673%0.728SS**  trans-127.8121.8-176.7-81.1-84.4000114.1
580P30.2Very low32.1Very low125 Ų125145.4 Ų145.481%0.81275%0.753SS**  trans-87.9144-174.633.8-34.8000113.5
581G29.7Very low31.5Very low67 Ų67146 Ų14669%0.69176%0.762SS**  trans110.245.2149.300000119.5
582F27.2Very low30.9Very low217 Ų217148.7 Ų148.795%0.95278%0.777SS**  trans-156.6117149.3-112.1-76.2000111.2
583A31.2Very low30.4Very low96 Ų96147.3 Ų147.379%0.79379%0.789SS**  trans-147110.7-176.800000113.1
584P32.4Very low30Very low119 Ų119147.4 Ų147.477%0.77380%0.798SS**  trans-88.6118.4176.332.7-31.1000112.2V586P584-V586 PolarHBondContact O-N 2.75Å
585R27.7Very low29.2Very low258 Ų258147.9 Ų147.997%0.97481%0.806SS**  trans-79.2106.2169.8-86.4-178.1166.7173.7-1.7111
586V28.9Very low28.8Very low133 Ų133149.6 Ų149.681%0.80681%0.808SS**  trans-112.8118.2169.5-177.60000110.1P584P584-V586 PolarHBondContact O-N 2.75Å
587K27.8Very low28.4Very low207 Ų207153.4 Ų153.490%0.982%0.822SS**  trans-92.6124.3169.3-82.5-173.8172.5-177.90110
588R25.5Very low28.1Very low223 Ų223154 Ų15484%0.84282%0.823SS**  trans-66.8137.5166.7-76-179.3173.91631.3110D566D566-R588 IonicContact OD2-NH2 3.34Å
589Q28.4Very low27.6Very low199 Ų199156.1 Ų156.193%0.9383%0.826SS**  trans-137150.3149.9-158.7165.80.200108.8
590R27Very low27.6Very low224 Ų224153.4 Ų153.485%0.84582%0.819SS**  trans-133.2124.4-161.3178.4-169-168.3177.14.7108.9
591N27.1Very low27.3Very low153 Ų153153.9 Ų153.982%0.81882%0.815SS**  trans172.3154.4138.5-89.9-11.9000114
592S27.7Very low27.3Very low117 Ų117157.4 Ų157.482%0.81882%0.817SS**  trans54.194.3146.8-167.50000120.4
593G25.7Very low27.2Very low75 Ų75151.5 Ų151.577%0.77380%0.803SS**  60.99612400000119.8
594S26.4Very low27Very low108 Ų108151 Ų15176%0.75579%0.794SS**  trans-164.1151.414341.50000110.6
595S25.3Very low26.9Very low129 Ų129152.8 Ų152.890%0.90280%0.795SS**  trans-76.8125.1171.6-59.90000109.8
596V27.3Very low26.9Very low116 Ų116145.7 Ų145.770%0.70379%0.785SS**  trans-114.2115.4178.8-178.90000110.7
597L23.4Very low26.9Very low152 Ų152143.8 Ų143.880%0.79678%0.783SS**  trans-62.7127.9171.2-122.279.7000110.4K599L597-K599 PolarHBondContact O-N 3.2Å
598F27.5Very low27Very low179 Ų179141 Ų14179%0.78578%0.784SS**  trans-94.484.8169.2-119.8-83.4000111.5L600F598-L600 HydrophobicContact CD1-CD1 4.34Å; F598-L600 HydrophobicContact CD1-CG 4.15Å; F598-L600 PolarHBondContact O-N 2.96Å
599K24.5Very low27.1Very low186 Ų186140.6 Ų140.681%0.80979%0.788SS**  trans-71.8110.8161.5-85.8-175.3172.6-1790108.7L597L597-K599 PolarHBondContact O-N 3.2Å
600L28.3Very low27.1Very low138 Ų138135.8 Ų135.872%0.72378%0.782SS**  trans-99.4106.8166.5-94.4164000110.3F598 L602F598-L600 HydrophobicContact CD1-CD1 4.34Å; F598-L600 HydrophobicContact CD1-CG 4.15Å; F598-L600 PolarHBondContact O-N 2.96Å; L600-L602 PolarHBondContact O-N 3.26Å
601N24.4Very low27.2Very low136 Ų136129 Ų12973%0.72778%0.775SS**  trans-83.999.5177.6-174.527.8000109.8S603N601-S603 PolarHBondContact O-N 3.11Å
602L30.4Very low27.3Very low140 Ų140129.4 Ų129.473%0.73377%0.771SS**  trans-94.761.3-179.2-89.2163.1000111.9L600 S604L600-L602 PolarHBondContact O-N 3.26Å; L602-S604 VanDerWaalsContact C-N 3.35Å; L602-S604 PolarHBondContact O-N 2.86Å
603S24.8Very low27.2Very low93 Ų93131.8 Ų131.865%0.6577%0.769SS**  trans-93.556174.763.80000112N601N601-S603 PolarHBondContact O-N 3.11Å
604S26.4Very low27.4Very low87 Ų87135 Ų13561%0.60877%0.774SS**  trans-162.3178.4171.164.80000110.8L602L602-S604 VanDerWaalsContact C-N 3.35Å; L602-S604 PolarHBondContact O-N 2.86Å
605I29.9Very low27.6Very low156 Ų156134.7 Ų134.780%0.877%0.769SS**  trans70.141.1-176-35.5177.8000113.5
606S28.1Very low27.7Very low109 Ų109138.1 Ų138.176%0.76277%0.768SS**  trans-80.7128146.555.20000109.7
607A28.5Very low28.1Very low92 Ų92137 Ų13776%0.7676%0.764SS**  trans57.5128.9166.300000119.6
608T30.7Very low28.3Very low150 Ų150136.8 Ų136.892%0.9276%0.763SS**  -172.3127.8126.714.70000110.7
609K27.6Very low28.4Very low213 Ų213134.5 Ų134.593%0.92676%0.764SS**  trans-162.373167.2-163.9-170.6-178.2-172.80112.3
610A28.4Very low28.6Very low98 Ų98132.4 Ų132.481%0.8176%0.761SS**  trans-167.1153.1162.700000112.5
611A29.6Very low28.7Very low83 Ų83132.7 Ų132.769%0.68676%0.763SS**  trans52.198.9151.400000121.6
612Q28Very low29.1Very low161 Ų161132.3 Ų132.375%0.75277%0.765SS**  59.4117.9119.8-70.4169.9-8200123.5
613Q26.3Very low29.1Very low166 Ų166132.8 Ų132.878%0.77677%0.768SS**  85.3149126.5-69.6177.5-28.300122.6
614V29.9Very low29.5Very low142 Ų142133.7 Ų133.786%0.86178%0.775SS**  trans82.1131.3169.2-162.80000117.4
615P30.9Very low29.7Very low103 Ų103134.7 Ų134.767%0.66978%0.778SS**  trans-127.9149.3-169.341.4-26.3000118.4
616F27.2Very low29.7Very low200 Ų200134 Ų13488%0.87777%0.774SS**  trans60.5171.2145.2-79.3-51.8000120.8
617P34.9Very low30Very low94 Ų94136.9 Ų136.961%0.6177%0.773SS**  cis-138.7-175.5-29.935.9-16.3000116.5
618N27.1Very low30.2Very low146 Ų146140.8 Ų140.878%0.78178%0.776SS**  trans79.8134.1150.9-64.3-20.3000123.2
619V30.8Very low30.5Very low132 Ų132139.2 Ų139.280%0.877%0.768SS**  167116.5112161.50000113.9
620N28.3Very low30.7Very low141 Ų141137.8 Ų137.875%0.75477%0.767SS**  trans2.8164.2139.3-57.6-6.2000122
621L29.8Very low31Very low145 Ų145138.5 Ų138.576%0.75976%0.761SS**  cis-165.4-171.32.1-144.276.2000112.7
622V34.1Very low31.1Very low128 Ų128141 Ų14178%0.77677%0.767SS**  trans109.9142.1150.7-1670000119.5
623D29.6Very low31.6Very low149 Ų149139 Ų13980%0.79777%0.768SS**  trans-99-167.9-169.3-70.5-98000114
624S33.2Very low31.8Very low113 Ų113135.8 Ų135.879%0.7977%0.771SS**  cis-164.2-159.826.676.10000119.2
625T30.5Very low31.9Very low108 Ų108133.2 Ų133.266%0.66376%0.764SS**  trans-93.9163.2-157.350.60000119.5
626L31.1Very low31.8Very low140 Ų140137 Ų13773%0.73377%0.77SS**  164.5137114.5-87.3162.3000118.3
627K33.3Very low31.8Very low171 Ų171135.1 Ų135.174%0.74376%0.764SS**  trans54.2157.6145.6-71.4175.9179.8174.20123
628Q32.5Very low31.5Very low173 Ų173137.1 Ų137.181%0.80877%0.769SS**  cis-165.9164.5-36.2-120178.5-36.500111.3
629P38.4Very low31.5Very low117 Ų117135.5 Ų135.576%0.7676%0.764SS**  trans-128.9175.3-165.844.7-32.7000118.9
630M31.5Very low31.2Very low184 Ų184136.3 Ų136.391%0.90676%0.764SS**  trans-162173.1169.7-83-157174.600111.4
631V33.4Very low31.3Very low112 Ų112139.1 Ų139.168%0.67977%0.773SS**  cis-167.5113.2-28.1144.50000108.4
632V32.5Very low31.1Very low135 Ų135138.6 Ų138.682%0.81878%0.776SS**  84.1148.1114.3176.20000117.9
633P38.6Very low30.7Very low119 Ų119137.5 Ų137.577%0.77377%0.773SS**  trans-133.7-151.3-147.247.4-31.1000117.4
634A30.3Very low30.5Very low100 Ų100138.2 Ų138.283%0.82677%0.772SS**  trans103150.6169.900000116.5
635A31.5Very low30.2Very low87 Ų87142.7 Ų142.772%0.71977%0.773SS**  cis-165.9162.5-14.100000114.4
636K28.9Very low30.2Very low183 Ų183142.6 Ų142.680%0.79677%0.774SS**  trans61.8139.4151.3-79.8-177.6176.3-176.90123.6
637Q28.6Very low29.9Very low161 Ų161140.4 Ų140.475%0.75277%0.771SS**  trans68.9149.8145.2-76.1175-70.200118.8
638L26.5Very low29.7Very low136 Ų136141.7 Ų141.771%0.71277%0.772SS**  cis-160.4162.7-17.3-16777.5000109.2
639T27.1Very low29.4Very low111 Ų111138.7 Ų138.768%0.68177%0.77SS**  trans69.6127154.526.40000121.6
640N26.1Very low28.9Very low149 Ų149143.6 Ų143.680%0.79777%0.774SS**  trans33.4109.4143.4-62.5-0.7000120.6
641Q29.8Very low28.8Very low201 Ų201144.6 Ų144.694%0.93977%0.773SS**  -154.4161.3124.8-116172.12900112.6
642T24.6Very low28.6Very low134 Ų134145.2 Ų145.282%0.82278%0.78SS**  trans-89.4129.1-175.347.10000112.8
643S26.8Very low28.4Very low104 Ų104144.2 Ų144.273%0.72778%0.779SS**  trans-174.4141.5138.252.50000114.7
644Q25Very low28Very low164 Ų164150.2 Ų150.277%0.76679%0.786SS**  trans39.8118.4133.8-67.2173.4-18.400122.2
645Y28.1Very low28.3Very low208 Ų208155.3 Ų155.382%0.81679%0.79SS**  trans71.2165140.3-76.3-58.9000117.4
646P29.7Very low28.6Very low105 Ų105156.2 Ų156.268%0.68279%0.788SS**  cis-118.9162.519.941.8-29.5000118.1
647S24.7Very low29.1Very low94 Ų94152.8 Ų152.866%0.65779%0.785SS**  trans-78.7133.316951.20000112.3S649S647-S649 PolarHBondContact O-N 3.24Å
648Y29.7Very low29.6Very low199 Ų199151.1 Ų151.178%0.7879%0.788SS**  trans-89.699.1170.4-84.3-82.1000111.8
649S26Very low30.5Very low110 Ų110153.1 Ų153.177%0.76980%0.796SS**  trans-86.3107.9172.755.20000111.5S647S647-S649 PolarHBondContact O-N 3.24Å
650W26.3Very low31.3Very low220 Ų220153.3 Ų153.383%0.83380%0.799SS**  trans-127.981.3172.2-8386.8000111
651F29.5Very low32.2Very low204 Ų204151.6 Ų151.690%0.89580%0.796SS**  trans-174.7126.1146.8-98.7-63.7000109.4S653F651-S653 PolarHBondContact O-N 2.77Å
652P29.9Very low32.9Very low126 Ų126147.5 Ų147.582%0.81879%0.787SS**  trans-80.3107.5179.530.6-33.1000111.6R654P652-R654 PolarHBondContact O-N 2.98Å
653S28Very low33.9Very low114 Ų114146.6 Ų146.680%0.79778%0.783SS**  trans-79.497.3177.657.10000112.5F651F651-S653 PolarHBondContact O-N 2.77Å
654R31.4Very low34.9Very low245 Ų245147.1 Ų147.193%0.92578%0.784SS**  trans-138.391.1158.9-78.6-165.2177.7-166.80.4110.8P652P652-R654 PolarHBondContact O-N 2.98Å
655F35.5Very low35.9Very low206 Ų206145.4 Ų145.490%0.90479%0.787SS**PPolyproline II helixtrans-74.8143.3156.1-84.3-90.7000109.2
656P38.2Very low36.8Very low106 Ų106139.7 Ų139.769%0.68878%0.783SS**PPolyproline II helixtrans-69.3157.4168.731.3-34.8000110.7
657P39.6Very low37.1Very low112 Ų112140.4 Ų140.473%0.72779%0.788SS**PPolyproline II helixtrans-65.6154.7172.230-35.4000111.1
658P39.3Very low37.8Very low125 Ų125141.4 Ų141.481%0.81280%0.795SS**PPolyproline II helixtrans-64.9142.4174.628.6-34.7000110.9
659M44.2Very low38Very low179 Ų179139.9 Ų139.988%0.88280%0.799SS**PPolyproline II helixtrans-64.9144.5171.8-74.1-173.6-74.100110.8
660P44Very low38.3Very low115 Ų115141.4 Ų141.475%0.74780%0.799SS**PPolyproline II helixtrans-65.9152.1171.430-35000110.7
661P45.6Very low38.5Very low113 Ų113136.7 Ų136.773%0.73480%0.799SS**PPolyproline II helixtrans-66.5151.6173.829.9-35.2000111
662P45Very low38.7Very low115 Ų115130.9 Ų130.975%0.74778%0.784SS**PPolyproline II helixtrans-63.9149.3170.829.1-34.9000110.7
663P45.6Very low38.9Very low115 Ų115136.6 Ų136.675%0.74779%0.789SS**PPolyproline II helixtrans-66150.4176.129.2-35.1000111.1
664P47.4Very low39.5Very low114 Ų114136.4 Ų136.474%0.7479%0.786SS**PPolyproline II helixtrans-66.7147.6174.729.6-34.9000111
665P47Very low39.6Very low128 Ų128130.7 Ų130.783%0.83178%0.78SS**PPolyproline II helixtrans-63.5137.3171.127.6-33.4000110.2
666A46.5Very low39.7Very low88 Ų88129 Ų12973%0.72778%0.779SS**PPolyproline II helixtrans-69.3146.7-177.600000112S668A666-S668 PolarHBondContact O-N 3.35Å
667P36Very low39.6Very low121 Ų121129.6 Ų129.679%0.78678%0.783SS**  trans-77.387.117932.1-34.8000110.9L669P667-L669 PolarHBondContact O-N 2.99Å; P667-L669 VanDerWaalsContact O-N 3.14Å
668S39.3Very low39.2Very low115 Ų115133.8 Ų133.880%0.80479%0.79SS**  trans-72.4100.8168.656.90000110.1A666 D670A666-S668 PolarHBondContact O-N 3.35Å; S668-D670 PolarHBondContact O-N 3.31Å
669L32.9Very low38.9Very low167 Ų167134.9 Ų134.987%0.87479%0.79SS**  trans-65.6120.8159.1-76.377000108.5P667P667-L669 PolarHBondContact O-N 2.99Å; P667-L669 VanDerWaalsContact O-N 3.14Å
670D33.6Very low38.7Very low141 Ų141131.1 Ų131.175%0.75478%0.779SS**  trans-144.5133.5137.3-161.1-21.7000108.7S668 S672S668-D670 PolarHBondContact O-N 3.31Å; D670-S672 PolarHBondContact OD1-OG 3.14Å
671S31.1Very low38.3Very low121 Ų121133.5 Ų133.585%0.84678%0.78SS**  trans-119.160.1-168.660.60000111.1
672S31.6Very low37.8Very low82 Ų82134.8 Ų134.857%0.57378%0.78SS**  trans-156.695.2173.859.70000116.1D670D670-S672 PolarHBondContact OD1-OG 3.14Å
673R34.4Very low37.3Very low246 Ų246134.2 Ų134.293%0.92878%0.776SS**  trans-176146.9135.5-97.8146.1-157-135.91.5112.8
674P40.6Very low36.6Very low111 Ų111136.8 Ų136.872%0.72178%0.778SS**  trans-84162.3-177.835.1-36.3000113.1
675P34.6Very low35.8Very low124 Ų124142.4 Ų142.481%0.80579%0.786SS**  trans-74.1151.9177.431.7-35.9000112.7
676L37.9Very low35.2Very low170 Ų170142.4 Ų142.489%0.8978%0.777SS**  trans-109.4152.8168.3-77.2170.8000110.9
677P35.7Very low34.4Very low119 Ų119144 Ų14477%0.77378%0.78SS**  trans-96168.7-154.337.1-37.6000115.9
678F31Very low34.3Very low200 Ų200143.8 Ų143.888%0.87778%0.777SS**  trans-56.2154168-88.3-104.6000113.5
679N34Very low33.9Very low149 Ų149146.6 Ų146.680%0.79778%0.777SS**  trans-137.4113.9153.3-171.210.4000110.2
680P38.3Very low33.7Very low100 Ų100146.2 Ų146.265%0.64978%0.776SS**  trans-109.3139.4-17637.2-29.6000114.1
681Q36.6Very low33.6Very low165 Ų165147.7 Ų147.777%0.77178%0.782SS**  trans-143.8112.9162.1-72.1-160.21.100109.5
682L34Very low33.6Very low140 Ų140149 Ų14973%0.73378%0.78SS**  87.4149.497.8-74.8167.3000113.5
683P35.6Very low33.6Very low103 Ų103150 Ų15067%0.66978%0.784SS**  cis-133.9165.7-20.237.2-19.9000115.8
684H30.7Very low33.3Very low169 Ų169147.7 Ų147.778%0.78278%0.781SS**  trans20.5128.8154.1-56.7-64.1000122.9
685Y31.6Very low32.8Very low232 Ų232151.1 Ų151.191%0.9179%0.79SS**  -138.5162.5127.9-144.5-99.1000111.6
686I34Very low32.7Very low127 Ų127153.5 Ų153.565%0.65180%0.795SS**  trans-109.9141.1-160.8-61.6168.9000111.5
687P29.4Very low32.3Very low121 Ų121149.8 Ų149.879%0.78678%0.781SS**  trans-89117.8174.833.3-32.2000113.3
688T34Very low32.1Very low118 Ų118151.6 Ų151.672%0.72478%0.784SS**  trans-135.5111.8165.141.20000108.4
689Q31Very low32.1Very low173 Ų173149.7 Ų149.781%0.80878%0.782SS**  72.2116.385.1-78-164.9-10.400115.7
690N28Very low31.8Very low159 Ų159154.3 Ų154.385%0.8579%0.789SS**  trans37.292.4148.7-69.7-6000119.5
691I32.5Very low31.6Very low172 Ų172156.8 Ų156.888%0.88280%0.796SS**  trans-132.3137145.5-58.7-176.5000109.1
692N30.6Very low31.3Very low150 Ų150154.2 Ų154.280%0.80279%0.793SS**  trans-76.4162.8-178.7-95.7-40.5000113.1
693P31.5Very low31Very low101 Ų101155.3 Ų155.366%0.65680%0.8SS**SBendtrans-71172.1-179.530.5-36.7000113.6
694F28.3Very low30.7Very low198 Ų198155.6 Ų155.687%0.86880%0.802SS**  trans72.683.5-178.7-62.1-90.5000116.8
695M29.6Very low30.9Very low183 Ų183155.9 Ų155.990%0.90180%0.801SS**  -162.6119.2124.3-112.8-174-72.200112
696L31.9Very low30.9Very low174 Ų174154.9 Ų154.991%0.91180%0.802SS**  trans-134.792.9165.7-107.5173.8000108.6
697P30Very low30.6Very low92 Ų92158.5 Ų158.560%0.59782%0.816SS**  trans-76.8155.3176.931.3-33.9000111.9
698N32.3Very low30.8Very low158 Ų158157.7 Ų157.785%0.84582%0.819SS**  trans69.833.1158.7-57.2-30.4000119.7R700N698-R700 PolarHBondContact O-N 2.98Å
699L29.7Very low30.5Very low159 Ų159164.7 Ų164.783%0.83284%0.844SS**  trans-88.397.8161-137.880000111.6L701L699-L701 PolarHBondContact O-N 3.38Å; L699-L701 VanDerWaalsContact O-N 3.15Å
700R29Very low30.5Very low247 Ų247164.3 Ų164.393%0.93285%0.845SS**  trans-75.296172.8-75.4-175.1176.7179-0.2110.7N698N698-R700 PolarHBondContact O-N 2.98Å
701L32.6Very low30.7Very low152 Ų152164.6 Ų164.680%0.79685%0.845SS**PPolyproline II helixtrans-70.7134.9166.2-76.9166.1000110.5L699 N703L699-L701 PolarHBondContact O-N 3.38Å; L699-L701 VanDerWaalsContact O-N 3.15Å; L701-N703 PolarHBondContact O-N 3.46Å
702P30.6Very low30.6Very low110 Ų110164.2 Ų164.271%0.71484%0.843SS**PPolyproline II helixtrans-77.2123.4177.129.8-32.7000111.4P704P702-P704 WeakPolarHBondContact O-CD 3.14Å
703N29.3Very low30.6Very low164 Ų164165 Ų16588%0.87785%0.846SS**PPolyproline II helixtrans-70.7129161.9-90.6-34.1000109.6L701L701-N703 PolarHBondContact O-N 3.46Å
704P29.2Very low30.5Very low109 Ų109169 Ų16971%0.70886%0.857SS**  trans-148.177.8133.336.7-19000113.1P702P702-P704 WeakPolarHBondContact O-CD 3.14Å
705F34Very low30.6Very low175 Ų175167.1 Ų167.177%0.76886%0.857SS**SBendtrans-140.66.2170.7-102.9-71.6000116.4
706F31.1Very low30.7Very low211 Ų211165.9 Ų165.993%0.92585%0.853SS**SBendtrans-136.645.5-179.7-94.5-81000113.3
707Q28.2Very low30.6Very low203 Ų203165.3 Ų165.395%0.94985%0.849SS**  trans-153.177.9170.2-128.6170.34.400114.2
708A33.8Very low30.7Very low103 Ų103171.4 Ų171.485%0.85187%0.87SS**  trans-148.9151.1156.500000107.7
709Q28.5Very low30.5Very low266 Ų266172.6 Ų172.6100%1.24387%0.872SS**  trans-88.40-170-68.8-177.2-45.500114.2

Retrieved 709 of 709 residues in 281.4 ms (Link to these results)