A0A077Z7K9_TRITR Loading...

Metalloendopeptidase

Metalloprotease.

AlphaFold DB , UniProt , Accession A0A077Z7K9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 314 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M27.1Very low57.9Low237 Ų23788.5 Ų88.5100%1.16744%0.44SS*.  0122.20-94.6171-85.300106.6A3M1-A3 PolarHBondContact O-N 2.76Å
2W25.6Very low59.5Low253 Ų25382.3 Ų82.396%0.95841%0.414SS*.  trans-72.2111.1-176.7-63.124.3000106.3Q4W2-Q4 PolarHBondContact O-N 2.84Å; W2-Q4 VanDerWaalsContact O-N 3.08Å
3A32.4Very low60.7Low81 Ų8178.8 Ų78.867%0.66941%0.411SS*.  trans-55.2117.5165.400000105.7M1 E5M1-A3 PolarHBondContact O-N 2.76Å; A3-E5 PolarHBondContact O-N 2.79Å
4Q49.6Very low62Low136 Ų13680.7 Ų80.764%0.63641%0.414SS*.  trans-65.4105.7174.9-85.1-178.1-17.600105.9W2 K6W2-Q4 PolarHBondContact O-N 2.84Å; W2-Q4 VanDerWaalsContact O-N 3.08Å; Q4-K6 PolarHBondContact O-N 3.07Å
5E60.7Low62.7Low160 Ų16076.3 Ų76.375%0.74840%0.395SS*.  trans-54.1114169.3-74.2179.4171.900106.9A3 R20A3-E5 PolarHBondContact O-N 2.79Å; E5-R20 VanDerWaalsContact C-NH2 3.35Å; E5-R20 VanDerWaalsContact O-CZ 3.23Å; E5-R20 PolarHBondContact O-NH1 3.26Å; E5-R20 PolarHBondContact O-NH2 2.68Å
6K70.3Confident63.2Low35 Ų3571.9 Ų71.915%0.15237%0.373CS..  trans-79.8147.3176.8-63.1166.7-178.6-178.50109Q4 G9 A12 R20 D90 C92 F93Q4-K6 PolarHBondContact O-N 3.07Å; K6-G9 WeakPolarHBondContact CB-O 3.47Å; K6-G9 WeakPolarHBondContact CD-O 3.47Å; K6-A12 HydrophobicContact CG-CB 4.38Å; K6-R20 PolarHBondContact O-NH2 3.03Å; K6-D90 VanDerWaalsContact CE-O 3.31Å; K6-D90 WeakPolarHBondContact CE-O 3.2Å; K6-D90 PolarHBondContact NZ-O 3.2Å; K6-C92 PolarHBondContact NZ-O 3.4Å; K6-F93 HydrophobicContact CD-CB 4.01Å; K6-F93 HydrophobicContact CD-CD1 4.29Å; K6-F93 HydrophobicContact CD-CG 4.45Å
7Y71.4Confident63.5Low18 Ų1872.3 Ų72.37%0.07138%0.379CS..BIsolated β-bridgetrans-81.1126.7173.9-178.1-98.4000107.9G9 I11 R19 R20 W128 E132Y7-G9 VanDerWaalsContact C-N 3.28Å; Y7-G9 PolarHBondContact O-N 3.24Å; Y7-I11 WeakPolarHBondContact CB-O 3.27Å; Y7-I11 HydrophobicContact CD1-CB 4.32Å; Y7-I11 HydrophobicContact CD1-CD1 4.44Å; Y7-I11 PolarHBondContact N-O 3.05Å; Y7-I11 VanDerWaalsContact O-CA 3.31Å; Y7-I11 WeakPolarHBondContact O-CA 3.45Å; Y7-I11 WeakPolarHBondContact O-CB 3.45Å; Y7-I11 WeakPolarHBondContact O-CG1 3.39Å; Y7-I11 PolarHBondContact O-N 3.45Å; Y7-R19 HydrophobicContact CE1-CG 4.35Å; Y7-R19 VanDerWaalsContact CE1-NH1 3.35Å; Y7-R19 VanDerWaalsContact CZ-CZ 3.47Å; Y7-R19 PolarHBondContact OH-NE 3.15Å; Y7-R19 VanDerWaalsContact OH-NE 3.09Å; Y7-R19 PolarHBondContact OH-NH2 2.89Å; Y7-R20 HydrophobicContact CD2-CG 4.21Å; Y7-W128 AromaticContact CD1-CZ3 3.87Å; Y7-W128 HydrophobicContact CD1-CZ3 3.87Å; Y7-W128 HydrophobicContact CE1-CE3 4.37Å; Y7-W128 AromaticContact CE1-CZ3 3.88Å; Y7-W128 HydrophobicContact CE1-CZ3 3.88Å; Y7-E132 PolarHBondContact OH-OE1 3.25Å
8Q70.9Confident63.8Low0 Ų073.4 Ų73.40%038%0.378CS..THydrogen-bonded Turntrans51.542.8-172.6-37.5-61.1-69.100113D10 I11 H129 E132 D153 Q154 Y178Q8-D10 PolarHBondContact O-N 2.9Å; Q8-I11 HydrophobicContact CB-CD1 4.32Å; Q8-I11 HydrophobicContact CG-CD1 4.33Å; Q8-H129 PolarHBondContact O-CE1 3.35Å; Q8-E132 WeakPolarHBondContact CG-OE1 3.35Å; Q8-E132 PolarHBondContact NE2-OE1 3.08Å; Q8-E132 PolarHBondContact OE1-OE1 3.16Å; Q8-D153 PolarHBondContact NE2-O 2.77Å; Q8-Q154 VanDerWaalsContact CD-CA 3.49Å; Q8-Q154 VanDerWaalsContact NE2-CA 3.34Å; Q8-Q154 VanDerWaalsContact OE1-CA 3.24Å; Q8-Q154 PolarHBondContact OE1-O 3.4Å; Q8-Y178 WeakPolarHBondContact CA-OH 3.4Å; Q8-Y178 VanDerWaalsContact CB-OH 3.26Å; Q8-Y178 WeakPolarHBondContact CB-OH 3.25Å; Q8-Y178 PolarHBondContact O-OH 3.37Å
9G73.4Confident63.8Low31 Ų3170.4 Ų70.432%0.3236%0.361SS..THydrogen-bonded Turntrans79.2-35.416800000115.3K6 Y7K6-G9 WeakPolarHBondContact CB-O 3.47Å; K6-G9 WeakPolarHBondContact CD-O 3.47Å; Y7-G9 VanDerWaalsContact C-N 3.28Å; Y7-G9 PolarHBondContact O-N 3.24Å
10D80.7Confident63.7Low22 Ų2272.3 Ų72.312%0.11836%0.363CS..THydrogen-bonded Turntrans-144.19.2-169.458.213.1000113.2Q8 F93 S94 H119 H123 H129Q8-D10 PolarHBondContact O-N 2.9Å; D10-F93 CarbonylContact O-C 3.54Å; D10-F93 WeakPolarHBondContact O-CA 3.5Å; D10-F93 WeakPolarHBondContact O-CB 2.96Å; D10-S94 PolarHBondContact O-N 2.75Å; D10-H119 IonicContact OD2-CD2 2.69Å; D10-H119 IonicContact OD2-NE2 3.71Å; D10-H119 PolarHBondContact OD2-NE2 2.84Å; D10-H123 IonicContact OD1-NE2 3.67Å; D10-H123 PolarHBondContact OD1-NE2 3.2Å; D10-H123 IonicContact OD2-NE2 3.18Å; D10-H129 IonicContact OD1-CE1 2.88Å; D10-H129 PolarHBondContact OD1-CE1 3.19Å; D10-H129 IonicContact OD1-NE2 2.77Å; D10-H129 PolarHBondContact OD1-NE2 3.04Å; D10-H129 IonicContact OD2-CE1 3.26Å; D10-H129 IonicContact OD2-NE2 2.83Å; D10-H129 PolarHBondContact OD2-NE2 3.12Å
11I75Confident63.1Low0 Ų075.7 Ų75.70%038%0.382CS..BIsolated β-bridgetrans-104.8116.3174.7-46.4-179.7000111.2Y7 Q8 A16 S94 V96 W128Y7-I11 WeakPolarHBondContact CB-O 3.27Å; Y7-I11 HydrophobicContact CD1-CB 4.32Å; Y7-I11 HydrophobicContact CD1-CD1 4.44Å; Y7-I11 PolarHBondContact N-O 3.05Å; Y7-I11 VanDerWaalsContact O-CA 3.31Å; Y7-I11 WeakPolarHBondContact O-CA 3.45Å; Y7-I11 WeakPolarHBondContact O-CB 3.45Å; Y7-I11 WeakPolarHBondContact O-CG1 3.39Å; Y7-I11 PolarHBondContact O-N 3.45Å; Q8-I11 HydrophobicContact CB-CD1 4.32Å; Q8-I11 HydrophobicContact CG-CD1 4.33Å; I11-A16 HydrophobicContact CG2-CB 4.16Å; I11-S94 VanDerWaalsContact CA-O 3.26Å; I11-S94 WeakPolarHBondContact CA-O 3.22Å; I11-S94 WeakPolarHBondContact CG2-O 3.29Å; I11-V96 HydrophobicContact CD1-CG2 3.89Å; I11-V96 HydrophobicContact CG1-CG2 4.44Å; I11-V96 HydrophobicContact CG2-CG2 3.72Å; I11-W128 HydrophobicContact CD1-CE3 3.38Å; I11-W128 HydrophobicContact CD1-CZ3 3.61Å; I11-W128 HydrophobicContact CG2-CZ3 3.9Å
12A77Confident64.3Low15 Ų1569.4 Ų69.412%0.12435%0.348CS..  trans-140.5139.6176.800000112.4K6 F93 S94 D95K6-A12 HydrophobicContact CG-CB 4.38Å; A12-F93 HydrophobicContact CB-CD2 3.65Å; A12-F93 HydrophobicContact CB-CE2 3.98Å; A12-F93 HydrophobicContact CB-CG 4.18Å; A12-S94 PolarHBondContact N-O 3.1Å; A12-S94 CarbonylContact O-C 3.6Å; A12-D95 WeakPolarHBondContact O-CA 3.25Å; A12-D95 WeakPolarHBondContact O-CB 3.25Å; A12-D95 PolarHBondContact O-N 2.8Å; A12-D95 VanDerWaalsContact O-N 3.09Å
13G75.6Confident65.3Low37 Ų3762.1 Ų62.138%0.38133%0.331SS..SBendtrans137.5-160.5179.600000113.5A16 V17 D95G13-A16 PolarHBondContact O-N 3.08Å; G13-V17 VanDerWaalsContact O-CG2 3.29Å; G13-V17 WeakPolarHBondContact O-CG2 3.45Å; G13-V17 PolarHBondContact O-N 3.07Å; G13-D95 VanDerWaalsContact CA-CG 3.48Å
14K77.9Confident65.9Low105 Ų10563.6 Ų63.646%0.45732%0.319SS..Hα-helixtrans-69-36.7-175.5-72171.6178.2172.10112.2R18 D95 G99 G100K14-R18 WeakPolarHBondContact O-CB 3.32Å; K14-R18 WeakPolarHBondContact O-CG 3.38Å; K14-R18 PolarHBondContact O-N 3.37Å; K14-D95 WeakPolarHBondContact CA-OD2 3.15Å; K14-D95 PolarHBondContact N-OD2 2.7Å; K14-G99 WeakPolarHBondContact CD-O 3.5Å; K14-G99 PolarHBondContact NZ-O 3.24Å; K14-G100 PolarHBondContact NZ-O 3.34Å
15A72.8Confident65.5Low15 Ų1559 Ų5912%0.12431%0.308CS..Hα-helixtrans-67.7-42.1175.400000110.5V17 R18 R19 D95 V96 W128A15-V17 PolarHBondContact O-N 2.83Å; A15-R18 PolarHBondContact O-N 3.23Å; A15-R19 WeakPolarHBondContact O-CB 3.44Å; A15-R19 PolarHBondContact O-N 2.95Å; A15-D95 WeakPolarHBondContact CA-OD1 3.27Å; A15-D95 WeakPolarHBondContact CB-OD1 3.4Å; A15-D95 VanDerWaalsContact N-CG 3.34Å; A15-D95 PolarHBondContact N-OD1 3.28Å; A15-D95 PolarHBondContact N-OD2 3.36Å; A15-V96 HydrophobicContact CB-CB 4.3Å; A15-V96 WeakPolarHBondContact CB-O 3.44Å; A15-W128 HydrophobicContact CB-CH2 4.33Å; A15-W128 HydrophobicContact CB-CZ2 4.39Å
16A71.3Confident64.5Low5 Ų552.3 Ų52.34%0.04128%0.278CS..Hα-helixtrans-57.5-48.3172.600000112.6I11 G13 R19 R20 D95I11-A16 HydrophobicContact CG2-CB 4.16Å; G13-A16 PolarHBondContact O-N 3.08Å; A16-R19 PolarHBondContact O-N 3.07Å; A16-R20 PolarHBondContact O-N 3.16Å; A16-D95 PolarHBondContact N-OD1 2.93Å; A16-D95 VanDerWaalsContact N-OD1 3.15Å
17V68.3Low63.4Low79 Ų7950.7 Ų50.748%0.47927%0.271SS..Hα-helixtrans-63-45.7178171.50000111.3G13 A15 R19 R20 L21G13-V17 VanDerWaalsContact O-CG2 3.29Å; G13-V17 WeakPolarHBondContact O-CG2 3.45Å; G13-V17 PolarHBondContact O-N 3.07Å; A15-V17 PolarHBondContact O-N 2.83Å; V17-R19 PolarHBondContact O-N 3.28Å; V17-R20 PolarHBondContact O-N 2.72Å; V17-L21 HydrophobicContact CG1-CD1 3.95Å; V17-L21 WeakPolarHBondContact O-CG 3.11Å; V17-L21 PolarHBondContact O-N 3.46Å; V17-L21 VanDerWaalsContact O-N 3.12Å
18R68.2Low62.5Low93 Ų9353 Ų5335%0.35128%0.28SS..Hα-helixtrans-58-36.4176-76.2171.1-176.4177.18.1111.5K14 A15 K22 D36K14-R18 WeakPolarHBondContact O-CB 3.32Å; K14-R18 WeakPolarHBondContact O-CG 3.38Å; K14-R18 PolarHBondContact O-N 3.37Å; A15-R18 PolarHBondContact O-N 3.23Å; R18-K22 WeakPolarHBondContact O-CB 3.4Å; R18-K22 VanDerWaalsContact O-CG 3.27Å; R18-K22 WeakPolarHBondContact O-CG 3.44Å; R18-K22 PolarHBondContact O-N 3Å; R18-D36 IonicContact NH1-OD1 3.01Å; R18-D36 PolarHBondContact NH1-OD1 2.74Å
19R63.9Low62Low16 Ų1653 Ų536%0.0628%0.28CS..Hα-helixtrans-74.1-44.3179-169.3166.6175.2-163.9-15.1112.3Y7 A15 A16 V17 L21 K22 W128 E132 G156 K157 A158Y7-R19 HydrophobicContact CE1-CG 4.35Å; Y7-R19 VanDerWaalsContact CE1-NH1 3.35Å; Y7-R19 VanDerWaalsContact CZ-CZ 3.47Å; Y7-R19 PolarHBondContact OH-NE 3.15Å; Y7-R19 VanDerWaalsContact OH-NE 3.09Å; Y7-R19 PolarHBondContact OH-NH2 2.89Å; A15-R19 WeakPolarHBondContact O-CB 3.44Å; A15-R19 PolarHBondContact O-N 2.95Å; A16-R19 PolarHBondContact O-N 3.07Å; V17-R19 PolarHBondContact O-N 3.28Å; R19-L21 PolarHBondContact O-N 3.45Å; R19-K22 CarbonylContact O-C 3.52Å; R19-K22 PolarHBondContact O-N 2.89Å; R19-W128 HydrophobicContact CB-CH2 4.29Å; R19-W128 VanDerWaalsContact CD-CH2 3.49Å; R19-W128 VanDerWaalsContact NH1-CZ3 3.27Å; R19-E132 IonicContact CZ-OE1 3.16Å; R19-E132 IonicContact CZ-OE2 2.67Å; R19-E132 VanDerWaalsContact NH1-CD 3.34Å; R19-E132 IonicContact NH1-OE1 3.75Å; R19-E132 PolarHBondContact NH1-OE1 3.37Å; R19-E132 IonicContact NH1-OE2 4Å; R19-E132 PolarHBondContact NH1-OE2 2.76Å; R19-E132 IonicContact NH2-OE1 3.6Å; R19-E132 PolarHBondContact NH2-OE1 3.12Å; R19-E132 IonicContact NH2-OE2 2.64Å; R19-G156 PolarHBondContact NH2-O 2.9Å; R19-K157 PolarHBondContact NH2-O 2.67Å; R19-A158 VanDerWaalsContact CZ-CA 3.4Å
20R61Low61.4Low108 Ų10851.5 Ų51.541%0.40827%0.265SS..Hα-helixtrans-55.3-37.3173.4-78.1-175.2169.2162.53.4112.8E5 K6 Y7 A16 V17 K22E5-R20 VanDerWaalsContact C-NH2 3.35Å; E5-R20 VanDerWaalsContact O-CZ 3.23Å; E5-R20 PolarHBondContact O-NH1 3.26Å; E5-R20 PolarHBondContact O-NH2 2.68Å; K6-R20 PolarHBondContact O-NH2 3.03Å; Y7-R20 HydrophobicContact CD2-CG 4.21Å; A16-R20 PolarHBondContact O-N 3.16Å; V17-R20 PolarHBondContact O-N 2.72Å; R20-K22 VanDerWaalsContact C-N 3.28Å; R20-K22 PolarHBondContact O-N 3.12Å
21L52.2Low60.9Low143 Ų14350.7 Ų50.775%0.74926%0.26SS*.THydrogen-bonded Turntrans-79.1-8.3178.9-65.1172.8000113.7V17 R19V17-L21 HydrophobicContact CG1-CD1 3.95Å; V17-L21 WeakPolarHBondContact O-CG 3.11Å; V17-L21 PolarHBondContact O-N 3.46Å; V17-L21 VanDerWaalsContact O-N 3.12Å; R19-L21 PolarHBondContact O-N 3.45Å
22K51.6Low60.5Low105 Ų10556.6 Ų56.646%0.45728%0.283SS..  trans-12382.7-175.6-70.4-178.8-172.5178.40111.4R18 R19 R20 R24 E162R18-K22 WeakPolarHBondContact O-CB 3.4Å; R18-K22 VanDerWaalsContact O-CG 3.27Å; R18-K22 WeakPolarHBondContact O-CG 3.44Å; R18-K22 PolarHBondContact O-N 3Å; R19-K22 CarbonylContact O-C 3.52Å; R19-K22 PolarHBondContact O-N 2.89Å; R20-K22 VanDerWaalsContact C-N 3.28Å; R20-K22 PolarHBondContact O-N 3.12Å; K22-R24 PolarHBondContact O-N 3.2Å; K22-R24 VanDerWaalsContact O-N 3.16Å; K22-E162 IonicContact NZ-OE1 3.81Å; K22-E162 PolarHBondContact NZ-OE1 3.03Å
23V46.2Very low60.1Low100 Ų10058.6 Ų58.661%0.60629%0.29SS*.  trans-73.8101.1160.9-174.90000106.7L288V23-L288 HydrophobicContact CG1-CD1 4.41Å
24R45.6Very low59.9Low112 Ų11262.6 Ų62.642%0.42331%0.308SS..  trans159.7125.1155.1-85.7152.2-164-137.34.1112.7K22 N159 L288 I289K22-R24 PolarHBondContact O-N 3.2Å; K22-R24 VanDerWaalsContact O-N 3.16Å; R24-N159 PolarHBondContact O-ND2 3.17Å; R24-L288 PolarHBondContact NH1-O 3.2Å; R24-L288 PolarHBondContact NH2-O 2.52Å; R24-I289 HydrophobicContact CB-CG2 4.21Å; R24-I289 VanDerWaalsContact CD-CG2 3.42Å; R24-I289 HydrophobicContact CG-CG2 3.41Å; R24-I289 VanDerWaalsContact CG-CG2 3.41Å
25G41.2Very low60Low39 Ų3962.5 Ų62.540%0.40231%0.307SS..  trans147.6146.3165.200000110.9
26V40.3Very low60.4Low21 Ų2162.6 Ų62.613%0.12731%0.306CS..  trans-65.1161.9164.4159.80000107.6W134 A158 N159 L160 L305V26-W134 HydrophobicContact CB-CB 4.25Å; V26-W134 HydrophobicContact CG1-CB 3.29Å; V26-W134 HydrophobicContact CG1-CD2 3.48Å; V26-W134 VanDerWaalsContact CG1-CD2 3.48Å; V26-W134 HydrophobicContact CG1-CE3 3.83Å; V26-W134 HydrophobicContact CG1-CG 3.23Å; V26-A158 CarbonylContact C-O 3.47Å; V26-N159 CarbonylContact O-C 3.6Å; V26-N159 WeakPolarHBondContact O-CA 3.15Å; V26-L160 VanDerWaalsContact C-CD2 3.45Å; V26-L160 HydrophobicContact CB-CD1 3.67Å; V26-L160 HydrophobicContact CB-CD2 3.97Å; V26-L160 HydrophobicContact CB-CG 3.5Å; V26-L160 HydrophobicContact CG1-CD1 3.71Å; V26-L160 HydrophobicContact CG1-CD2 3.56Å; V26-L160 HydrophobicContact CG1-CG 3.64Å; V26-L160 VanDerWaalsContact O-CA 3.22Å; V26-L160 WeakPolarHBondContact O-CA 3.47Å; V26-L160 VanDerWaalsContact O-CB 3.25Å; V26-L160 WeakPolarHBondContact O-CB 3.31Å; V26-L160 WeakPolarHBondContact O-CD2 3.29Å; V26-L160 WeakPolarHBondContact O-CG 3.48Å; V26-L160 PolarHBondContact O-N 3.03Å; V26-L305 HydrophobicContact CB-CD1 3.81Å; V26-L305 HydrophobicContact CB-CD2 4.39Å; V26-L305 HydrophobicContact CG1-CD1 4.46Å; V26-L305 HydrophobicContact CG1-CD2 4.23Å; V26-L305 HydrophobicContact CG2-CD1 3.15Å; V26-L305 HydrophobicContact CG2-CD2 3.63Å; V26-L305 HydrophobicContact CG2-CG 3.99Å
27A46Very low61.3Low0 Ų064.4 Ų64.40%031%0.312CS..  trans-121.7124.1-163.500000119.9E132 R133 W134 K157 A158 F165A27-E132 WeakPolarHBondContact CB-O 3.26Å; A27-R133 CarbonylContact O-C 3.59Å; A27-W134 HydrophobicContact CB-CB 3.78Å; A27-W134 WeakPolarHBondContact O-CA 3.35Å; A27-W134 WeakPolarHBondContact O-CB 2.98Å; A27-W134 PolarHBondContact O-N 3.06Å; A27-K157 HydrophobicContact CB-CB 3.63Å; A27-A158 WeakPolarHBondContact CA-O 3.37Å; A27-A158 HydrophobicContact CB-CB 3.63Å; A27-A158 WeakPolarHBondContact CB-O 3.12Å; A27-A158 PolarHBondContact N-O 2.93Å; A27-F165 WeakPolarHBondContact O-CE1 3.16Å; A27-F165 VanDerWaalsContact O-CZ 3.23Å; A27-F165 WeakPolarHBondContact O-CZ 3.45Å
28R53.9Low62.6Low66 Ų6661 Ų6125%0.24929%0.291CS..  trans-108.3169.1168.5-63.6170.5-161.9165.3-2.7111A158 L160 S163 D164 F165R28-A158 VanDerWaalsContact O-CB 3.24Å; R28-A158 WeakPolarHBondContact O-CB 3.23Å; R28-L160 HydrophobicContact CG-CD2 3.56Å; R28-S163 WeakPolarHBondContact CA-OG 3.13Å; R28-S163 WeakPolarHBondContact CB-O 3.46Å; R28-S163 WeakPolarHBondContact CB-OG 3.49Å; R28-S163 VanDerWaalsContact CD-O 3.31Å; R28-S163 WeakPolarHBondContact CD-O 3.26Å; R28-S163 PolarHBondContact N-OG 3.42Å; R28-S163 WeakPolarHBondContact O-CB 3.2Å; R28-S163 PolarHBondContact O-OG 2.97Å; R28-D164 VanDerWaalsContact CB-C 3.49Å; R28-D164 VanDerWaalsContact CB-N 3.27Å; R28-D164 IonicContact NH1-OD2 2.65Å; R28-F165 HydrophobicContact CB-CD1 3.73Å; R28-F165 HydrophobicContact CB-CE1 3.78Å; R28-F165 HydrophobicContact CB-CG 4.22Å; R28-F165 HydrophobicContact CB-CZ 4.33Å; R28-F165 HydrophobicContact CG-CD1 4Å; R28-F165 HydrophobicContact CG-CD2 4.1Å; R28-F165 HydrophobicContact CG-CE1 3.94Å; R28-F165 HydrophobicContact CG-CE2 4.11Å; R28-F165 HydrophobicContact CG-CG 4.07Å; R28-F165 HydrophobicContact CG-CZ 3.99Å
29N59.7Low63.8Low0 Ų060 Ų600%030%0.297CS..SBendtrans-108.20.6-16878.4-35000116.7F127 W128 E130 R133 D164 F165 K215N29-F127 CarbonylContact O-C 3.44Å; N29-F127 VanDerWaalsContact O-CA 3.27Å; N29-F127 WeakPolarHBondContact O-CA 3.35Å; N29-F127 VanDerWaalsContact O-CD1 3.27Å; N29-F127 WeakPolarHBondContact O-CD1 3.47Å; N29-W128 PolarHBondContact O-N 2.93Å; N29-E130 PolarHBondContact ND2-OE2 2.81Å; N29-R133 HydrophobicContact CB-CG 3.9Å; N29-D164 PolarHBondContact N-O 3.45Å; N29-D164 PolarHBondContact OD1-O 3.19Å; N29-F165 HydrophobicContact CB-CD1 4.44Å; N29-K215 WeakPolarHBondContact ND2-CE 3.31Å; N29-K215 PolarHBondContact ND2-NZ 3.18Å
30G61.5Low65.1Low0 Ų065.9 Ų65.90%033%0.329CS..EExtended strand (participates in β ladder)trans-135.6144.9172.600000113.9R32 G126 S163 D164G30-R32 PolarHBondContact O-N 2.68Å; G30-G126 CarbonylContact C-O 3.45Å; G30-G126 VanDerWaalsContact CA-O 3.26Å; G30-G126 WeakPolarHBondContact CA-O 3.45Å; G30-S163 CarbonylContact O-C 3.53Å; G30-S163 VanDerWaalsContact O-C 3.25Å; G30-S163 WeakPolarHBondContact O-CA 3.27Å; G30-S163 WeakPolarHBondContact O-CB 3.27Å; G30-D164 PolarHBondContact N-O 3.47Å; G30-D164 PolarHBondContact O-N 3.17Å
31V68.8Low66.8Low5 Ų562.9 Ų62.93%0.0332%0.321CS..EExtended strand (participates in β ladder)trans-55.1128.5-171.2-68.30000112.9D36 K37 V96 G126 E162 Y166 M219V31-D36 HydrophobicContact CB-CB 4.1Å; V31-D36 HydrophobicContact CG1-CB 4.15Å; V31-K37 HydrophobicContact CG2-CG 4.03Å; V31-K37 WeakPolarHBondContact O-CE 3.34Å; V31-V96 HydrophobicContact CG1-CG1 3.77Å; V31-G126 WeakPolarHBondContact CG1-O 3.22Å; V31-G126 PolarHBondContact N-O 3.1Å; V31-E162 CarbonylContact C-O 3.49Å; V31-E162 VanDerWaalsContact CA-O 3.28Å; V31-E162 WeakPolarHBondContact CA-O 3.41Å; V31-Y166 PolarHBondContact O-OH 3.46Å; V31-M219 HydrophobicContact CG2-CE 4.19Å; V31-M219 HydrophobicContact CG2-SD 3.72Å
32R67.5Low68.9Low124 Ų12459.8 Ų59.847%0.46830%0.303SS..  trans-93.4-42.7-176-176.6178.3164.1-159.1-5.5113.1G30 L160 E162G30-R32 PolarHBondContact O-N 2.68Å; R32-L160 PolarHBondContact NH1-O 3.5Å; R32-E162 PolarHBondContact N-O 2.86Å
33M68.7Low71.1Confident57 Ų5754.8 Ų54.828%0.28128%0.281SS..SBendtrans-72.2132.8-174.4-65.1-174-79.500110.3K35 D36 E162M33-K35 HydrophobicContact CB-CG 3.98Å; M33-K35 PolarHBondContact O-N 3.37Å; M33-K35 VanDerWaalsContact O-N 3.14Å; M33-K35 VanDerWaalsContact SD-CE 3.57Å; M33-D36 WeakPolarHBondContact CB-OD2 3.47Å; M33-D36 WeakPolarHBondContact CE-OD2 3.47Å; M33-D36 PolarHBondContact O-N 2.91Å; M33-E162 HydrophobicContact CE-CB 4.44Å; M33-E162 HydrophobicContact CE-CG 3.85Å
34T71.3Confident73.6Confident122 Ų12250.4 Ų50.475%0.74826%0.255SS*.G310 helixtrans-55.8-32.8179.149.40000112.6D36 K37T34-D36 PolarHBondContact O-N 3.11Å; T34-K37 PolarHBondContact O-N 2.7Å; T34-K37 VanDerWaalsContact O-N 3.17Å
35K79.4Confident76.1Confident103 Ų10347.2 Ų47.245%0.44824%0.243SC..G310 helixtrans-63.9-26.8175.970.6174-172.3179.10113.5M33 K37 R98M33-K35 HydrophobicContact CB-CG 3.98Å; M33-K35 PolarHBondContact O-N 3.37Å; M33-K35 VanDerWaalsContact O-N 3.14Å; M33-K35 VanDerWaalsContact SD-CE 3.57Å; K35-K37 VanDerWaalsContact C-N 3.32Å; K35-R98 VanDerWaalsContact O-CZ 3.23Å; K35-R98 PolarHBondContact O-NE 3.38Å; K35-R98 PolarHBondContact O-NH2 3.41Å
36D82.8Confident78.9Confident17 Ų1747.8 Ų47.89%0.09124%0.239CC..G310 helixtrans-93.3-0.5-179.5-54.1-42.3000110.9R18 V31 M33 T34 G97 R98R18-D36 IonicContact NH1-OD1 3.01Å; R18-D36 PolarHBondContact NH1-OD1 2.74Å; V31-D36 HydrophobicContact CB-CB 4.1Å; V31-D36 HydrophobicContact CG1-CB 4.15Å; M33-D36 WeakPolarHBondContact CB-OD2 3.47Å; M33-D36 WeakPolarHBondContact CE-OD2 3.47Å; M33-D36 PolarHBondContact O-N 2.91Å; T34-D36 PolarHBondContact O-N 3.11Å; D36-G97 CarbonylContact O-C 3.4Å; D36-G97 WeakPolarHBondContact O-CA 3.3Å; D36-R98 PolarHBondContact O-N 2.82Å
37K89.1Confident81.6Confident42 Ų4248.7 Ų48.718%0.18324%0.243CC..SBendtrans-88.7152.4169.3-59.9-177.2-176.9-171.40110.5V31 T34 K35 R98 M219 Y220V31-K37 HydrophobicContact CG2-CG 4.03Å; V31-K37 WeakPolarHBondContact O-CE 3.34Å; T34-K37 PolarHBondContact O-N 2.7Å; T34-K37 VanDerWaalsContact O-N 3.17Å; K35-K37 VanDerWaalsContact C-N 3.32Å; K37-R98 PolarHBondContact O-NE 3.13Å; K37-M219 HydrophobicContact CD-CG 4.28Å; K37-M219 PolarHBondContact NZ-O 2.94Å; K37-Y220 HydrophobicContact CB-CE1 4.43Å
38W95.1Very high83.9Confident7 Ų748.8 Ų48.83%0.02724%0.244CC..PPolyproline II helixtrans-77.3129.2172.1-67.393.1000110.9E42 I43 D82 L84 R98 A124 Y220W38-E42 WeakPolarHBondContact CB-O 3.49Å; W38-I43 HydrophobicContact CB-CG1 3.9Å; W38-I43 HydrophobicContact CD2-CB 4.31Å; W38-I43 HydrophobicContact CD2-CG1 3.98Å; W38-I43 HydrophobicContact CD2-CG2 3.98Å; W38-I43 HydrophobicContact CE3-CG2 4.24Å; W38-I43 HydrophobicContact CG-CB 4.43Å; W38-I43 HydrophobicContact CG-CD1 4.05Å; W38-I43 HydrophobicContact CG-CG1 3.61Å; W38-I43 HydrophobicContact CG-CG2 4.49Å; W38-I43 HydrophobicContact CH2-CG2 4.34Å; W38-I43 HydrophobicContact CZ2-CG2 4.07Å; W38-I43 HydrophobicContact CZ3-CG2 4.41Å; W38-D82 HydrophobicContact CZ3-CB 4.12Å; W38-L84 HydrophobicContact CH2-CD2 4.2Å; W38-L84 HydrophobicContact CH2-CG 4.28Å; W38-L84 HydrophobicContact CZ2-CD2 3.84Å; W38-L84 HydrophobicContact CZ2-CG 4.14Å; W38-R98 HydrophobicContact CD2-CB 3.85Å; W38-R98 HydrophobicContact CD2-CG 3.99Å; W38-R98 HydrophobicContact CE3-CB 4.33Å; W38-R98 HydrophobicContact CE3-CG 3.93Å; W38-R98 HydrophobicContact CG-CB 4.14Å; W38-R98 HydrophobicContact CH2-CG 4.15Å; W38-R98 HydrophobicContact CZ2-CB 4.18Å; W38-R98 HydrophobicContact CZ2-CG 4.2Å; W38-R98 HydrophobicContact CZ3-CG 4.02Å; W38-A124 PolarHBondContact NE1-O 2.77Å; W38-Y220 HydrophobicContact CB-CE1 4.46Å
39P93.1Very high85.8Confident74 Ų7453.4 Ų53.448%0.48127%0.268SS..G310 helixtrans-59.8146.8179-23.633.6000112.4N41 E42P39-N41 PolarHBondContact O-N 3.09Å; P39-E42 PolarHBondContact O-N 3.25Å
40N93.1Very high87.3Confident139 Ų13961.3 Ų61.374%0.74330%0.303SS*.G310 helixtrans55.817.3177.1-52.3-34.2000114.9E42N40-E42 HydrophobicContact CB-CG 4.41Å; N40-E42 PolarHBondContact O-N 2.79Å
41N94.9Very high88.9Confident44 Ų4461.8 Ų61.824%0.23531%0.305CS..G310 helixtrans60.916.9-172.6-43.5-18.7000112.6P39 C71 V72 R73 Y220P39-N41 PolarHBondContact O-N 3.09Å; N41-C71 WeakPolarHBondContact CB-O 3.1Å; N41-C71 PolarHBondContact ND2-SG 3.05Å; N41-V72 CarbonylContact O-C 3.58Å; N41-V72 WeakPolarHBondContact O-CA 3.31Å; N41-R73 PolarHBondContact O-N 3.42Å; N41-Y220 HydrophobicContact CB-CD1 3.96Å; N41-Y220 PolarHBondContact ND2-O 2.96Å; N41-Y220 VanDerWaalsContact OD1-CD1 3.25Å; N41-Y220 WeakPolarHBondContact OD1-CD1 3.49Å
42E97.5Very high90.2Very high79 Ų7964.2 Ų64.237%0.36932%0.322SS..EExtended strand (participates in β ladder)trans-101.2130-179.2-71.8-174.717500110.7W38 P39 N40 P44 R73 V75W38-E42 WeakPolarHBondContact CB-O 3.49Å; P39-E42 PolarHBondContact O-N 3.25Å; N40-E42 HydrophobicContact CB-CG 4.41Å; N40-E42 PolarHBondContact O-N 2.79Å; E42-P44 WeakPolarHBondContact O-CD 3.34Å; E42-R73 CarbonylContact C-O 3.56Å; E42-R73 VanDerWaalsContact CA-O 3.3Å; E42-R73 WeakPolarHBondContact CA-O 3.42Å; E42-R73 HydrophobicContact CG-CB 4.29Å; E42-V75 HydrophobicContact CB-CG2 4.24Å; E42-V75 HydrophobicContact CG-CG1 4.37Å
43I98.3Very high91.6Very high0 Ų063.3 Ų63.30%034%0.335CS..EExtended strand (participates in β ladder)trans-114.396.2175.9-51.6-172.8000107.3W38 V72 R73 F74 V75 L84 V125W38-I43 HydrophobicContact CB-CG1 3.9Å; W38-I43 HydrophobicContact CD2-CB 4.31Å; W38-I43 HydrophobicContact CD2-CG1 3.98Å; W38-I43 HydrophobicContact CD2-CG2 3.98Å; W38-I43 HydrophobicContact CE3-CG2 4.24Å; W38-I43 HydrophobicContact CG-CB 4.43Å; W38-I43 HydrophobicContact CG-CD1 4.05Å; W38-I43 HydrophobicContact CG-CG1 3.61Å; W38-I43 HydrophobicContact CG-CG2 4.49Å; W38-I43 HydrophobicContact CH2-CG2 4.34Å; W38-I43 HydrophobicContact CZ2-CG2 4.07Å; W38-I43 HydrophobicContact CZ3-CG2 4.41Å; I43-V72 HydrophobicContact CD1-CG1 3.78Å; I43-V72 HydrophobicContact CG1-CG1 4.1Å; I43-R73 PolarHBondContact N-O 2.79Å; I43-F74 HydrophobicContact CB-CD1 3.8Å; I43-F74 HydrophobicContact CB-CE1 3.91Å; I43-F74 HydrophobicContact CD1-CD1 4.45Å; I43-F74 HydrophobicContact CD1-CE1 3.74Å; I43-F74 HydrophobicContact CD1-CZ 4.01Å; I43-F74 HydrophobicContact CG1-CE1 4.32Å; I43-F74 HydrophobicContact CG2-CD1 3.99Å; I43-F74 HydrophobicContact CG2-CE1 3.91Å; I43-F74 WeakPolarHBondContact O-CA 3.07Å; I43-V75 PolarHBondContact O-N 3.02Å; I43-V75 VanDerWaalsContact O-N 3.09Å; I43-L84 HydrophobicContact CG2-CD1 3.46Å; I43-L84 VanDerWaalsContact CG2-CD1 3.46Å; I43-L84 HydrophobicContact CG2-CG 3.71Å; I43-V125 HydrophobicContact CD1-CG2 3.73Å
44P98.5Very high92.8Very high7 Ų768.8 Ų68.85%0.04536%0.357CS..EExtended strand (participates in β ladder)trans-64.1136.3176.5-19.732.5000110.3E42 V75 R77 Q80 Y83 L84E42-P44 WeakPolarHBondContact O-CD 3.34Å; P44-V75 CarbonylContact C-O 3.54Å; P44-V75 VanDerWaalsContact CA-O 3.23Å; P44-V75 WeakPolarHBondContact CA-O 3.26Å; P44-V75 HydrophobicContact CB-CG2 4.36Å; P44-V75 HydrophobicContact CG-CG2 4.33Å; P44-R77 HydrophobicContact CB-CB 4.03Å; P44-R77 HydrophobicContact CB-CG 4.15Å; P44-Q80 HydrophobicContact CB-CB 4.04Å; P44-Q80 HydrophobicContact CB-CG 4.09Å; P44-Q80 HydrophobicContact CG-CB 3.7Å; P44-Q80 HydrophobicContact CG-CG 3.53Å; P44-Y83 CarbonylContact O-C 3.48Å; P44-Y83 VanDerWaalsContact O-CA 3.26Å; P44-Y83 WeakPolarHBondContact O-CA 3.33Å; P44-Y83 WeakPolarHBondContact O-CB 3.4Å; P44-L84 PolarHBondContact O-N 3.48Å
45Y98.6Very high94Very high45 Ų4565 Ų6518%0.17633%0.331CS..EExtended strand (participates in β ladder)trans-133.9154.9178.374.3-88.5000113.6L47 M63 F74 V75 P76 R77 L84 I86Y45-L47 HydrophobicContact CD2-CD2 3.78Å; Y45-L47 HydrophobicContact CD2-CG 3.87Å; Y45-L47 HydrophobicContact CE2-CD1 4.13Å; Y45-L47 HydrophobicContact CE2-CD2 3.9Å; Y45-L47 HydrophobicContact CE2-CG 3.68Å; Y45-M63 HydrophobicContact CD1-CE 3.97Å; Y45-M63 HydrophobicContact CD1-SD 4.25Å; Y45-M63 HydrophobicContact CD2-CE 3.98Å; Y45-M63 HydrophobicContact CE1-CE 4.08Å; Y45-M63 HydrophobicContact CE1-SD 3.8Å; Y45-M63 HydrophobicContact CE2-CE 4.1Å; Y45-M63 HydrophobicContact CE2-SD 4.32Å; Y45-M63 HydrophobicContact CG-CE 3.92Å; Y45-F74 HydrophobicContact CD1-CB 3.95Å; Y45-F74 HydrophobicContact CE1-CB 4.01Å; Y45-V75 VanDerWaalsContact CD1-C 3.49Å; Y45-V75 WeakPolarHBondContact CD1-O 2.94Å; Y45-V75 VanDerWaalsContact CE1-C 3.43Å; Y45-V75 PolarHBondContact N-O 3.44Å; Y45-P76 HydrophobicContact CE1-CG 4.46Å; Y45-R77 WeakPolarHBondContact O-CB 3.05Å; Y45-R77 PolarHBondContact O-N 3.24Å; Y45-L84 CarbonylContact C-O 3.48Å; Y45-L84 WeakPolarHBondContact CA-O 3.38Å; Y45-I86 HydrophobicContact CD2-CD1 4.32Å; Y45-I86 HydrophobicContact CG-CD1 4.34Å
46V98.2Very high94.8Very high52 Ų5264 Ų6432%0.31532%0.324SS..EExtended strand (participates in β ladder)trans-124.1130.2166178.50000107.3R77 Y83 L84 Y85 I86V46-R77 HydrophobicContact CG2-CB 3.8Å; V46-R77 HydrophobicContact CG2-CG 4.42Å; V46-Y83 HydrophobicContact CB-CD2 4.49Å; V46-Y83 HydrophobicContact CB-CE2 4.4Å; V46-Y83 HydrophobicContact CG2-CD2 3.96Å; V46-Y83 HydrophobicContact CG2-CE2 3.94Å; V46-L84 PolarHBondContact N-O 3.42Å; V46-Y85 HydrophobicContact CB-CD2 4.36Å; V46-Y85 HydrophobicContact CG1-CD2 4.26Å; V46-I86 PolarHBondContact O-N 3.15Å
47L97.6Very high95.5Very high39 Ų3965.6 Ų65.620%0.20434%0.339CS..EExtended strand (participates in β ladder)trans-89.3134.5172-60.8-179.5000109.8Y45 R56 I59 I86Y45-L47 HydrophobicContact CD2-CD2 3.78Å; Y45-L47 HydrophobicContact CD2-CG 3.87Å; Y45-L47 HydrophobicContact CE2-CD1 4.13Å; Y45-L47 HydrophobicContact CE2-CD2 3.9Å; Y45-L47 HydrophobicContact CE2-CG 3.68Å; L47-R56 HydrophobicContact CD1-CG 4.45Å; L47-I59 HydrophobicContact CD2-CD1 4.46Å; L47-I59 HydrophobicContact CD2-CG2 4.07Å; L47-I86 CarbonylContact C-O 3.46Å; L47-I86 HydrophobicContact CD2-CB 3.83Å; L47-I86 HydrophobicContact CD2-CD1 3.99Å; L47-I86 HydrophobicContact CD2-CG1 4.47Å; L47-I86 HydrophobicContact CD2-CG2 4.02Å
48G95.3Very high95.9Very high3 Ų364.7 Ų64.73%0.03134%0.338CS..  trans-56153.7168.900000111.9F50 R56 I86G48-F50 PolarHBondContact O-N 3.31Å; G48-R56 PolarHBondContact O-NH2 2.64Å; G48-I86 PolarHBondContact N-O 2.64Å
49E92.4Very high96Very high163 Ų16364.4 Ų64.476%0.76234%0.337SS*.THydrogen-bonded Turntrans-69.9-34.9-173.3-63.5-178.4171.200112Y51 R56E49-Y51 PolarHBondContact O-N 2.95Å; E49-R56 PolarHBondContact O-NH2 2.91Å
50F91.5Very high96.3Very high165 Ų16563.5 Ų63.572%0.72434%0.335SS*.THydrogen-bonded Turntrans-8025.3-170.9-55.7-69.7000116.3G48 R88G48-F50 PolarHBondContact O-N 3.31Å; F50-R88 PolarHBondContact O-NE 3.03Å
51Y95.3Very high96.5Very high10 Ų1064.4 Ų64.44%0.03933%0.328CS..  trans-98.2128.2168.2-66.3-57.8000110.8E49 E55 R56 I59 I86 G87 R88 L107 L112E49-Y51 PolarHBondContact O-N 2.95Å; Y51-E55 HydrophobicContact CD1-CB 4.23Å; Y51-R56 PolarHBondContact O-NE 2.79Å; Y51-I59 HydrophobicContact CD1-CD1 4.37Å; Y51-I59 HydrophobicContact CD2-CD1 4.04Å; Y51-I59 HydrophobicContact CE1-CD1 4.32Å; Y51-I59 HydrophobicContact CE2-CD1 3.95Å; Y51-I59 HydrophobicContact CG-CD1 4.24Å; Y51-I86 HydrophobicContact CE2-CG2 4.25Å; Y51-I86 WeakPolarHBondContact CE2-O 3.37Å; Y51-G87 WeakPolarHBondContact OH-CA 2.92Å; Y51-G87 PolarHBondContact OH-N 3.05Å; Y51-G87 PolarHBondContact OH-O 2.89Å; Y51-R88 HydrophobicContact CE1-CG 4Å; Y51-L107 WeakPolarHBondContact CE1-O 3.07Å; Y51-L107 PolarHBondContact OH-O 3.26Å; Y51-L112 HydrophobicContact CD1-CD1 4.08Å; Y51-L112 HydrophobicContact CD1-CD2 4.32Å; Y51-L112 HydrophobicContact CE1-CD1 3.97Å; Y51-L112 HydrophobicContact CE1-CD2 3.94Å
52S95.7Very high96.6Very high56 Ų5662.3 Ų62.339%0.39232%0.317SS..  trans-64.2162.5169.967.40000111.6K54 E55 R56S52-K54 PolarHBondContact O-N 2.67Å; S52-E55 WeakPolarHBondContact CB-OE2 3.31Å; S52-E55 PolarHBondContact N-OE2 2.73Å; S52-E55 PolarHBondContact O-N 3.27Å; S52-E55 VanDerWaalsContact O-N 3.13Å; S52-E55 VanDerWaalsContact OG-CG 3.23Å; S52-E55 WeakPolarHBondContact OG-CG 3.49Å; S52-E55 PolarHBondContact OG-N 2.97Å; S52-E55 PolarHBondContact OG-OE2 2.81Å; S52-R56 WeakPolarHBondContact O-CG 3.48Å; S52-R56 PolarHBondContact O-N 3.48Å
53S96.5Very high96.7Very high105 Ų10558.8 Ų58.873%0.73430%0.301SS*.Hα-helixtrans-57.3-34.7176.5-52.10000112.8A57S53-A57 WeakPolarHBondContact O-CB 3.31Å; S53-A57 PolarHBondContact O-N 2.81Å; S53-A57 VanDerWaalsContact O-N 3.07Å
54K95.3Very high96.7Very high173 Ų17363.2 Ų63.275%0.75232%0.321SS*.Hα-helixtrans-65.8-46176.9-175.3-179.9177.7-175.30111.1S52 A57 V58S52-K54 PolarHBondContact O-N 2.67Å; K54-A57 WeakPolarHBondContact O-CB 3.46Å; K54-A57 PolarHBondContact O-N 3.01Å; K54-V58 WeakPolarHBondContact O-CG2 3.26Å; K54-V58 PolarHBondContact O-N 3.24Å; K54-V58 VanDerWaalsContact O-N 3.15Å
55E95.9Very high96.6Very high41 Ų4163.1 Ų63.119%0.19232%0.321CS..Hα-helixtrans-67.2-42.3-179.2-66.6164.8142.700111.4Y51 S52 A57 V58 I59 R88 L112Y51-E55 HydrophobicContact CD1-CB 4.23Å; S52-E55 WeakPolarHBondContact CB-OE2 3.31Å; S52-E55 PolarHBondContact N-OE2 2.73Å; S52-E55 PolarHBondContact O-N 3.27Å; S52-E55 VanDerWaalsContact O-N 3.13Å; S52-E55 VanDerWaalsContact OG-CG 3.23Å; S52-E55 WeakPolarHBondContact OG-CG 3.49Å; S52-E55 PolarHBondContact OG-N 2.97Å; S52-E55 PolarHBondContact OG-OE2 2.81Å; E55-A57 PolarHBondContact O-N 3.49Å; E55-V58 PolarHBondContact O-N 2.75Å; E55-V58 VanDerWaalsContact O-N 3.07Å; E55-I59 WeakPolarHBondContact O-CG1 3.09Å; E55-I59 PolarHBondContact O-N 2.9Å; E55-R88 IonicContact OE1-CZ 2.64Å; E55-R88 IonicContact OE1-NH2 3.03Å; E55-R88 PolarHBondContact OE1-NH2 2.91Å; E55-R88 IonicContact OE2-NH2 2.89Å; E55-R88 PolarHBondContact OE2-NH2 2.85Å; E55-L112 HydrophobicContact CB-CD1 4.03Å; E55-L112 HydrophobicContact CB-CD2 4.4Å; E55-L112 HydrophobicContact CG-CD1 3.68Å; E55-L112 VanDerWaalsContact OE1-CD1 3.26Å; E55-L112 WeakPolarHBondContact OE1-CD1 3.42Å
56R97.3Very high96.5Very high84 Ų8461 Ų6132%0.31731%0.313SS..Hα-helixtrans-57.2-38.1171.8-69177.3-178.5-85.4-4.8112L47 G48 E49 Y51 S52 I59 A60L47-R56 HydrophobicContact CD1-CG 4.45Å; G48-R56 PolarHBondContact O-NH2 2.64Å; E49-R56 PolarHBondContact O-NH2 2.91Å; Y51-R56 PolarHBondContact O-NE 2.79Å; S52-R56 WeakPolarHBondContact O-CG 3.48Å; S52-R56 PolarHBondContact O-N 3.48Å; R56-I59 PolarHBondContact O-N 2.53Å; R56-A60 VanDerWaalsContact O-CB 3.29Å; R56-A60 WeakPolarHBondContact O-CB 3.01Å; R56-A60 PolarHBondContact O-N 2.94Å
57A97.5Very high96.5Very high49 Ų4960.5 Ų60.541%0.40531%0.307SS..Hα-helixtrans-68.4-32.4176.700000113.1S53 K54 E55 R61S53-A57 WeakPolarHBondContact O-CB 3.31Å; S53-A57 PolarHBondContact O-N 2.81Å; S53-A57 VanDerWaalsContact O-N 3.07Å; K54-A57 WeakPolarHBondContact O-CB 3.46Å; K54-A57 PolarHBondContact O-N 3.01Å; E55-A57 PolarHBondContact O-N 3.49Å; A57-R61 WeakPolarHBondContact O-CB 3.15Å; A57-R61 PolarHBondContact O-N 3.16Å
58V96.4Very high96.4Very high24 Ų2462.7 Ų62.715%0.14532%0.319CS..Hα-helixtrans-70.8-46.6173.5-171.90000110.2K54 E55 A60 R61 S62 I117K54-V58 WeakPolarHBondContact O-CG2 3.26Å; K54-V58 PolarHBondContact O-N 3.24Å; K54-V58 VanDerWaalsContact O-N 3.15Å; E55-V58 PolarHBondContact O-N 2.75Å; E55-V58 VanDerWaalsContact O-N 3.07Å; V58-A60 VanDerWaalsContact C-N 3.33Å; V58-A60 PolarHBondContact O-N 2.85Å; V58-R61 WeakPolarHBondContact O-CB 3.22Å; V58-R61 PolarHBondContact O-N 3.12Å; V58-R61 VanDerWaalsContact O-N 3.1Å; V58-S62 PolarHBondContact O-N 3.44Å; V58-S62 PolarHBondContact O-OG 2.03Å; V58-I117 HydrophobicContact CB-CD1 4.34Å; V58-I117 HydrophobicContact CG1-CD1 3.77Å
59I97.8Very high96.4Very high1 Ų165.3 Ų65.31%0.00533%0.328CS..Hα-helixtrans-56.8-47.5175.8-64167.3000110.8L47 Y51 E55 R56 R61 S62 M63 I86 L107 L112 I117L47-I59 HydrophobicContact CD2-CD1 4.46Å; L47-I59 HydrophobicContact CD2-CG2 4.07Å; Y51-I59 HydrophobicContact CD1-CD1 4.37Å; Y51-I59 HydrophobicContact CD2-CD1 4.04Å; Y51-I59 HydrophobicContact CE1-CD1 4.32Å; Y51-I59 HydrophobicContact CE2-CD1 3.95Å; Y51-I59 HydrophobicContact CG-CD1 4.24Å; E55-I59 WeakPolarHBondContact O-CG1 3.09Å; E55-I59 PolarHBondContact O-N 2.9Å; R56-I59 PolarHBondContact O-N 2.53Å; I59-R61 VanDerWaalsContact C-N 3.31Å; I59-R61 PolarHBondContact O-N 3.27Å; I59-S62 PolarHBondContact O-N 3.01Å; I59-M63 HydrophobicContact CG2-CE 3.77Å; I59-M63 HydrophobicContact CG2-SD 4.24Å; I59-M63 WeakPolarHBondContact O-CG 3.41Å; I59-M63 PolarHBondContact O-N 3.07Å; I59-I86 HydrophobicContact CD1-CG2 4.48Å; I59-L107 HydrophobicContact CD1-CD1 4.28Å; I59-L107 HydrophobicContact CG1-CD1 4.12Å; I59-L112 HydrophobicContact CD1-CD2 3.99Å; I59-L112 HydrophobicContact CG1-CD2 4.06Å; I59-I117 HydrophobicContact CG1-CD1 3.92Å
60A98.1Very high96.6Very high55 Ų5557.5 Ų57.546%0.45529%0.292SS..Hα-helixtrans-61-39.5177.600000112.2R56 V58 M63 Q64R56-A60 VanDerWaalsContact O-CB 3.29Å; R56-A60 WeakPolarHBondContact O-CB 3.01Å; R56-A60 PolarHBondContact O-N 2.94Å; V58-A60 VanDerWaalsContact C-N 3.33Å; V58-A60 PolarHBondContact O-N 2.85Å; A60-M63 PolarHBondContact O-N 2.99Å; A60-Q64 WeakPolarHBondContact O-CB 3.31Å; A60-Q64 PolarHBondContact O-N 3.48Å
61R97.8Very high96.9Very high157 Ų15750.3 Ų50.359%0.59226%0.262SS*.Hα-helixtrans-64.8-42.5176.1-172.2-171-51.3176.74112.2A57 V58 I59 Q64 A65 Y114A57-R61 WeakPolarHBondContact O-CB 3.15Å; A57-R61 PolarHBondContact O-N 3.16Å; V58-R61 WeakPolarHBondContact O-CB 3.22Å; V58-R61 PolarHBondContact O-N 3.12Å; V58-R61 VanDerWaalsContact O-N 3.1Å; I59-R61 VanDerWaalsContact C-N 3.31Å; I59-R61 PolarHBondContact O-N 3.27Å; R61-Q64 WeakPolarHBondContact O-CB 3.45Å; R61-Q64 PolarHBondContact O-N 2.89Å; R61-A65 PolarHBondContact O-N 3.25Å; R61-A65 VanDerWaalsContact O-N 3.09Å; R61-Y114 HydrophobicContact CG-CD2 4.41Å
62S97.9Very high97Very high0 Ų049.9 Ų49.90%026%0.26CS..Hα-helixtrans-65.7-40.7176.4-60.70000111.5V58 I59 Q64 A65 Y66 Y114V58-S62 PolarHBondContact O-N 3.44Å; V58-S62 PolarHBondContact O-OG 2.03Å; I59-S62 PolarHBondContact O-N 3.01Å; S62-Q64 VanDerWaalsContact C-N 3.34Å; S62-Q64 PolarHBondContact O-N 2.02Å; S62-A65 WeakPolarHBondContact O-CB 3.22Å; S62-A65 PolarHBondContact O-N 3.44Å; S62-Y66 WeakPolarHBondContact O-CD2 2.97Å; S62-Y114 WeakPolarHBondContact OG-CD2 3.4Å; S62-Y114 PolarHBondContact OG-O 3.45Å
63M98.4Very high97.1Very high6 Ų650.8 Ų50.83%0.0326%0.255CS..Hα-helixtrans-62.3-40.2171.8-70.2177.717600112.1Y45 I59 A60 A65 Y66 H67 F74 I86 L121Y45-M63 HydrophobicContact CD1-CE 3.97Å; Y45-M63 HydrophobicContact CD1-SD 4.25Å; Y45-M63 HydrophobicContact CD2-CE 3.98Å; Y45-M63 HydrophobicContact CE1-CE 4.08Å; Y45-M63 HydrophobicContact CE1-SD 3.8Å; Y45-M63 HydrophobicContact CE2-CE 4.1Å; Y45-M63 HydrophobicContact CE2-SD 4.32Å; Y45-M63 HydrophobicContact CG-CE 3.92Å; I59-M63 HydrophobicContact CG2-CE 3.77Å; I59-M63 HydrophobicContact CG2-SD 4.24Å; I59-M63 WeakPolarHBondContact O-CG 3.41Å; I59-M63 PolarHBondContact O-N 3.07Å; A60-M63 PolarHBondContact O-N 2.99Å; M63-A65 VanDerWaalsContact C-N 3.28Å; M63-A65 PolarHBondContact O-N 2.02Å; M63-Y66 WeakPolarHBondContact O-CB 3.45Å; M63-Y66 PolarHBondContact O-N 2.89Å; M63-Y66 VanDerWaalsContact O-N 3.15Å; M63-H67 PolarHBondContact O-CD2 3.31Å; M63-H67 PolarHBondContact O-N 3.29Å; M63-H67 VanDerWaalsContact O-N 3.17Å; M63-F74 HydrophobicContact CB-CB 4.24Å; M63-F74 HydrophobicContact CB-CD2 4.04Å; M63-F74 HydrophobicContact CB-CG 4.36Å; M63-F74 HydrophobicContact CE-CB 4.26Å; M63-F74 HydrophobicContact CE-CD1 4.38Å; M63-F74 HydrophobicContact CE-CG 4.38Å; M63-F74 HydrophobicContact CG-CB 3.92Å; M63-F74 HydrophobicContact CG-CD2 3.89Å; M63-F74 HydrophobicContact CG-CG 3.87Å; M63-F74 HydrophobicContact SD-CB 3.75Å; M63-F74 HydrophobicContact SD-CG 4.23Å; M63-I86 HydrophobicContact CE-CD1 3.33Å; M63-L121 HydrophobicContact CG-CD1 4Å
64Q97.8Very high97.2Very high92 Ų9246.1 Ų46.143%0.4322%0.221SC..Hα-helixtrans-61.1-37.6177.3-171.463.145.500111.8A60 R61 S62 Y66 H67 D68A60-Q64 WeakPolarHBondContact O-CB 3.31Å; A60-Q64 PolarHBondContact O-N 3.48Å; R61-Q64 WeakPolarHBondContact O-CB 3.45Å; R61-Q64 PolarHBondContact O-N 2.89Å; S62-Q64 VanDerWaalsContact C-N 3.34Å; S62-Q64 PolarHBondContact O-N 2.02Å; Q64-Y66 VanDerWaalsContact C-N 3.25Å; Q64-Y66 PolarHBondContact O-N 3.47Å; Q64-H67 WeakPolarHBondContact O-CA 3.45Å; Q64-H67 WeakPolarHBondContact O-CB 3.31Å; Q64-H67 PolarHBondContact O-N 3.32Å; Q64-D68 PolarHBondContact NE2-OD1 2.84Å; Q64-D68 VanDerWaalsContact O-CG 3.26Å; Q64-D68 PolarHBondContact O-N 2.76Å
65A96.9Very high97.3Very high5 Ų539.4 Ų39.44%0.04119%0.194CC..Hα-helixtrans-59.8-34.8176.500000113.1R61 S62 M63 R69 Y114 I118 F208R61-A65 PolarHBondContact O-N 3.25Å; R61-A65 VanDerWaalsContact O-N 3.09Å; S62-A65 WeakPolarHBondContact O-CB 3.22Å; S62-A65 PolarHBondContact O-N 3.44Å; M63-A65 VanDerWaalsContact C-N 3.28Å; M63-A65 PolarHBondContact O-N 2.02Å; A65-R69 WeakPolarHBondContact O-CG 3.19Å; A65-R69 PolarHBondContact O-N 3.26Å; A65-Y114 HydrophobicContact CB-CE2 3.97Å; A65-Y114 WeakPolarHBondContact CB-OH 3.04Å; A65-I118 HydrophobicContact CB-CD1 3.7Å; A65-F208 HydrophobicContact CB-CE2 4.18Å
66Y97.7Very high97.4Very high0 Ų041.6 Ų41.60%021%0.212CC..Hα-helixtrans-67-42.8169.5-78.4-90.2000111.9S62 M63 Q64 D68 R69 T70 F74 I118 L121 M122 V125 F208 I216S62-Y66 WeakPolarHBondContact O-CD2 2.97Å; M63-Y66 WeakPolarHBondContact O-CB 3.45Å; M63-Y66 PolarHBondContact O-N 2.89Å; M63-Y66 VanDerWaalsContact O-N 3.15Å; Q64-Y66 VanDerWaalsContact C-N 3.25Å; Q64-Y66 PolarHBondContact O-N 3.47Å; Y66-D68 VanDerWaalsContact C-N 3.3Å; Y66-D68 PolarHBondContact O-N 3.42Å; Y66-R69 PolarHBondContact O-N 2Å; Y66-T70 WeakPolarHBondContact O-CA 3.03Å; Y66-T70 WeakPolarHBondContact O-CB 3.3Å; Y66-T70 PolarHBondContact O-N 3.3Å; Y66-T70 PolarHBondContact O-OG1 2.94Å; Y66-F74 HydrophobicContact CD1-CE2 4.14Å; Y66-F74 HydrophobicContact CD2-CD2 4.49Å; Y66-F74 AromaticContact CD2-CE2 3.62Å; Y66-F74 HydrophobicContact CD2-CE2 3.62Å; Y66-F74 HydrophobicContact CD2-CZ 4.38Å; Y66-F74 HydrophobicContact CE2-CE2 4.16Å; Y66-F74 HydrophobicContact CE2-CZ 4.49Å; Y66-F74 HydrophobicContact CG-CD2 4.47Å; Y66-F74 AromaticContact CG-CE2 3.62Å; Y66-F74 HydrophobicContact CG-CE2 3.62Å; Y66-F74 HydrophobicContact CG-CZ 4.5Å; Y66-I118 HydrophobicContact CE2-CD1 4.26Å; Y66-I118 HydrophobicContact CE2-CG2 4.38Å; Y66-I118 PolarHBondContact OH-O 2.68Å; Y66-L121 HydrophobicContact CD2-CD1 4.29Å; Y66-L121 HydrophobicContact CE2-CB 3.6Å; Y66-L121 HydrophobicContact CE2-CD1 3.94Å; Y66-L121 HydrophobicContact CE2-CG 4.45Å; Y66-M122 WeakPolarHBondContact OH-CA 3.3Å; Y66-M122 WeakPolarHBondContact OH-CB 3.29Å; Y66-M122 PolarHBondContact OH-N 2.86Å; Y66-V125 HydrophobicContact CD1-CG2 4.29Å; Y66-V125 HydrophobicContact CE1-CG2 3.77Å; Y66-F208 HydrophobicContact CD1-CE1 4.31Å; Y66-F208 AromaticContact CD1-CZ 3.78Å; Y66-F208 HydrophobicContact CD1-CZ 3.78Å; Y66-F208 AromaticContact CD2-CZ 3.77Å; Y66-F208 HydrophobicContact CD2-CZ 3.77Å; Y66-F208 AromaticContact CE1-CE1 3.63Å; Y66-F208 HydrophobicContact CE1-CE1 3.63Å; Y66-F208 AromaticContact CE1-CZ 3.48Å; Y66-F208 HydrophobicContact CE1-CZ 3.48Å; Y66-F208 VanDerWaalsContact CE1-CZ 3.48Å; Y66-F208 HydrophobicContact CE2-CE1 4.15Å; Y66-F208 HydrophobicContact CE2-CE2 4.5Å; Y66-F208 AromaticContact CE2-CZ 3.49Å; Y66-F208 HydrophobicContact CE2-CZ 3.49Å; Y66-F208 VanDerWaalsContact CE2-CZ 3.49Å; Y66-F208 AromaticContact CG-CZ 3.9Å; Y66-F208 HydrophobicContact CG-CZ 3.9Å; Y66-F208 AromaticContact CZ-CE1 3.53Å; Y66-F208 AromaticContact CZ-CZ 3.32Å; Y66-F208 WeakPolarHBondContact OH-CE1 3.18Å; Y66-I216 HydrophobicContact CE1-CD1 4.11Å
67H97Very high97.5Very high42 Ų4241.8 Ų41.819%0.19421%0.213CC..Hα-helixtrans-64.1-38-177-63.6-175.1000111.9M63 Q64 R73 F74M63-H67 PolarHBondContact O-CD2 3.31Å; M63-H67 PolarHBondContact O-N 3.29Å; M63-H67 VanDerWaalsContact O-N 3.17Å; Q64-H67 WeakPolarHBondContact O-CA 3.45Å; Q64-H67 WeakPolarHBondContact O-CB 3.31Å; Q64-H67 PolarHBondContact O-N 3.32Å; H67-R73 PolarHBondContact O-NH1 2.92Å; H67-R73 PolarHBondContact O-NH2 3.12Å; H67-F74 AromaticContact NE2-CD2 4Å; H67-F74 PolarHBondContact NE2-N 3.28Å; H67-F74 VanDerWaalsContact NE2-N 3.19Å
68D95.3Very high97.4Very high86 Ų8644 Ų4446%0.4622%0.222SC..Hα-helixtrans-71.6-32.9-178.3-68-15.5000112.6Q64 Y66 M229Q64-D68 PolarHBondContact NE2-OD1 2.84Å; Q64-D68 VanDerWaalsContact O-CG 3.26Å; Q64-D68 PolarHBondContact O-N 2.76Å; Y66-D68 VanDerWaalsContact C-N 3.3Å; Y66-D68 PolarHBondContact O-N 3.42Å; D68-M229 WeakPolarHBondContact O-CE 2.91Å
69R96Very high97.4Very high57 Ų5752.2 Ų52.222%0.21525%0.251CS..Hα-helixtrans-117.6-6.9-166.1-56.6173.1-167.1157.4-11.3114.1A65 Y66 Y114 D207 L213 N217 Y226A65-R69 WeakPolarHBondContact O-CG 3.19Å; A65-R69 PolarHBondContact O-N 3.26Å; Y66-R69 PolarHBondContact O-N 2Å; R69-Y114 PolarHBondContact NH1-OH 3.07Å; R69-D207 IonicContact CZ-OD1 2.81Å; R69-D207 IonicContact CZ-OD2 2.85Å; R69-D207 VanDerWaalsContact CZ-OD2 3.29Å; R69-D207 IonicContact NH1-OD1 2.66Å; R69-D207 PolarHBondContact NH1-OD1 3.2Å; R69-D207 IonicContact NH1-OD2 3.61Å; R69-D207 PolarHBondContact NH1-OD2 2.74Å; R69-D207 IonicContact NH2-OD2 3.17Å; R69-D207 PolarHBondContact NH2-OD2 2.89Å; R69-L213 HydrophobicContact CB-CD1 4.12Å; R69-L213 HydrophobicContact CB-CD2 3.74Å; R69-N217 PolarHBondContact O-ND2 3.16Å; R69-N217 VanDerWaalsContact O-ND2 3.16Å; R69-Y226 WeakPolarHBondContact O-CD1 3.16Å
70T96.6Very high97.3Very high0 Ų054.1 Ų54.10%026%0.26CS..SBendtrans-140.6171.3178.681.10000111.3Y66 V72 R73 L213 I216 N217 Y226Y66-T70 WeakPolarHBondContact O-CA 3.03Å; Y66-T70 WeakPolarHBondContact O-CB 3.3Å; Y66-T70 PolarHBondContact O-N 3.3Å; Y66-T70 PolarHBondContact O-OG1 2.94Å; T70-V72 VanDerWaalsContact C-N 3.35Å; T70-V72 PolarHBondContact OG1-N 2.77Å; T70-V72 VanDerWaalsContact OG1-N 3.1Å; T70-R73 PolarHBondContact O-NH1 3.36Å; T70-L213 HydrophobicContact CG2-CD2 3.9Å; T70-I216 HydrophobicContact CG2-CB 4.25Å; T70-I216 HydrophobicContact CG2-CD1 4.42Å; T70-I216 HydrophobicContact CG2-CG2 3.75Å; T70-N217 WeakPolarHBondContact CA-OD1 3.38Å; T70-N217 VanDerWaalsContact CB-OD1 3.31Å; T70-N217 WeakPolarHBondContact CB-OD1 3.41Å; T70-Y226 VanDerWaalsContact O-CE1 3.24Å; T70-Y226 WeakPolarHBondContact O-CE1 3.25Å; T70-Y226 PolarHBondContact O-OH 3.44Å
71C96.7Very high97.2Very high14 Ų1455.6 Ų55.610%0.09527%0.267CS..SBendtrans-89.33.7170.168.10000113.8N41 C222 Y226N41-C71 WeakPolarHBondContact CB-O 3.1Å; N41-C71 PolarHBondContact ND2-SG 3.05Å; C71-C222 HydrophobicContact CB-CB 3.59Å; C71-C222 WeakPolarHBondContact CB-SG 3.45Å; C71-C222 PolarHBondContact N-SG 2.66Å; C71-C222 WeakPolarHBondContact SG-CA 3.44Å; C71-C222 WeakPolarHBondContact SG-CB 3.06Å; C71-C222 CovalentContact SG-SG 2.02Å; C71-C222 PolarHBondContact SG-SG 3.38Å; C71-Y226 HydrophobicContact CB-CD2 4.41Å; C71-Y226 HydrophobicContact CB-CE2 4.04Å
72V97.9Very high97.2Very high0 Ų049.6 Ų49.60%025%0.247CC..  trans-73.4137.3175.2177.90000109.7N41 I43 T70 F74 V125 I216 Y220N41-V72 CarbonylContact O-C 3.58Å; N41-V72 WeakPolarHBondContact O-CA 3.31Å; I43-V72 HydrophobicContact CD1-CG1 3.78Å; I43-V72 HydrophobicContact CG1-CG1 4.1Å; T70-V72 VanDerWaalsContact C-N 3.35Å; T70-V72 PolarHBondContact OG1-N 2.77Å; T70-V72 VanDerWaalsContact OG1-N 3.1Å; V72-F74 HydrophobicContact CG1-CE2 4.37Å; V72-V125 HydrophobicContact CG1-CG2 4.15Å; V72-I216 HydrophobicContact CG2-CG2 3.93Å; V72-Y220 HydrophobicContact CG2-CD1 4.43Å; V72-Y220 HydrophobicContact CG2-CD2 3.49Å; V72-Y220 VanDerWaalsContact CG2-CD2 3.49Å; V72-Y220 HydrophobicContact CG2-CE2 3.73Å; V72-Y220 HydrophobicContact CG2-CG 3.87Å
73R98.1Very high97.2Very high76 Ų7651.2 Ų51.229%0.28725%0.253SS..EExtended strand (participates in β ladder)trans-127.5111.9-177.3-64.7-64176.6-94.73.5111N41 E42 I43 H67 T70 V75 Y226N41-R73 PolarHBondContact O-N 3.42Å; E42-R73 CarbonylContact C-O 3.56Å; E42-R73 VanDerWaalsContact CA-O 3.3Å; E42-R73 WeakPolarHBondContact CA-O 3.42Å; E42-R73 HydrophobicContact CG-CB 4.29Å; I43-R73 PolarHBondContact N-O 2.79Å; H67-R73 PolarHBondContact O-NH1 2.92Å; H67-R73 PolarHBondContact O-NH2 3.12Å; T70-R73 PolarHBondContact O-NH1 3.36Å; R73-V75 HydrophobicContact CB-CG1 4.1Å; R73-V75 PolarHBondContact O-N 2.95Å; R73-Y226 PolarHBondContact NH2-OH 3.32Å
74F98.6Very high97.1Very high7 Ų750.9 Ų50.93%0.03125%0.252CS..EExtended strand (participates in β ladder)trans-76.6116.4164.5-64-80.7000109.2I43 Y45 M63 Y66 H67 V72 L84 L121 V125I43-F74 HydrophobicContact CB-CD1 3.8Å; I43-F74 HydrophobicContact CB-CE1 3.91Å; I43-F74 HydrophobicContact CD1-CD1 4.45Å; I43-F74 HydrophobicContact CD1-CE1 3.74Å; I43-F74 HydrophobicContact CD1-CZ 4.01Å; I43-F74 HydrophobicContact CG1-CE1 4.32Å; I43-F74 HydrophobicContact CG2-CD1 3.99Å; I43-F74 HydrophobicContact CG2-CE1 3.91Å; I43-F74 WeakPolarHBondContact O-CA 3.07Å; Y45-F74 HydrophobicContact CD1-CB 3.95Å; Y45-F74 HydrophobicContact CE1-CB 4.01Å; M63-F74 HydrophobicContact CB-CB 4.24Å; M63-F74 HydrophobicContact CB-CD2 4.04Å; M63-F74 HydrophobicContact CB-CG 4.36Å; M63-F74 HydrophobicContact CE-CB 4.26Å; M63-F74 HydrophobicContact CE-CD1 4.38Å; M63-F74 HydrophobicContact CE-CG 4.38Å; M63-F74 HydrophobicContact CG-CB 3.92Å; M63-F74 HydrophobicContact CG-CD2 3.89Å; M63-F74 HydrophobicContact CG-CG 3.87Å; M63-F74 HydrophobicContact SD-CB 3.75Å; M63-F74 HydrophobicContact SD-CG 4.23Å; Y66-F74 HydrophobicContact CD1-CE2 4.14Å; Y66-F74 HydrophobicContact CD2-CD2 4.49Å; Y66-F74 AromaticContact CD2-CE2 3.62Å; Y66-F74 HydrophobicContact CD2-CE2 3.62Å; Y66-F74 HydrophobicContact CD2-CZ 4.38Å; Y66-F74 HydrophobicContact CE2-CE2 4.16Å; Y66-F74 HydrophobicContact CE2-CZ 4.49Å; Y66-F74 HydrophobicContact CG-CD2 4.47Å; Y66-F74 AromaticContact CG-CE2 3.62Å; Y66-F74 HydrophobicContact CG-CE2 3.62Å; Y66-F74 HydrophobicContact CG-CZ 4.5Å; H67-F74 AromaticContact NE2-CD2 4Å; H67-F74 PolarHBondContact NE2-N 3.28Å; H67-F74 VanDerWaalsContact NE2-N 3.19Å; V72-F74 HydrophobicContact CG1-CE2 4.37Å; F74-L84 HydrophobicContact CE1-CD1 4.28Å; F74-L121 HydrophobicContact CD1-CD2 4.31Å; F74-L121 HydrophobicContact CE1-CD2 3.66Å; F74-L121 HydrophobicContact CE1-CG 4.49Å; F74-L121 HydrophobicContact CE2-CD1 4.28Å; F74-L121 HydrophobicContact CZ-CB 3.92Å; F74-L121 HydrophobicContact CZ-CD1 4.19Å; F74-L121 HydrophobicContact CZ-CD2 3.86Å; F74-L121 HydrophobicContact CZ-CG 4.21Å; F74-V125 HydrophobicContact CZ-CG2 3.94Å
75V98.3Very high97.1Very high31 Ų3149 Ų4919%0.18824%0.241CC..EExtended strand (participates in β ladder)trans-121.2139.6-174.8-62.30000110.4E42 I43 P44 Y45 R73 R77E42-V75 HydrophobicContact CB-CG2 4.24Å; E42-V75 HydrophobicContact CG-CG1 4.37Å; I43-V75 PolarHBondContact O-N 3.02Å; I43-V75 VanDerWaalsContact O-N 3.09Å; P44-V75 CarbonylContact C-O 3.54Å; P44-V75 VanDerWaalsContact CA-O 3.23Å; P44-V75 WeakPolarHBondContact CA-O 3.26Å; P44-V75 HydrophobicContact CB-CG2 4.36Å; P44-V75 HydrophobicContact CG-CG2 4.33Å; Y45-V75 VanDerWaalsContact CD1-C 3.49Å; Y45-V75 WeakPolarHBondContact CD1-O 2.94Å; Y45-V75 VanDerWaalsContact CE1-C 3.43Å; Y45-V75 PolarHBondContact N-O 3.44Å; R73-V75 HydrophobicContact CB-CG1 4.1Å; R73-V75 PolarHBondContact O-N 2.95Å; V75-R77 PolarHBondContact O-N 2.9Å
76P97.9Very high97.2Very high88 Ų8848.7 Ų48.757%0.57124%0.239SC*.EExtended strand (participates in β ladder)trans-55.7127.5171.5-2534.7000110.2Y45Y45-P76 HydrophobicContact CE1-CG 4.46Å
77R97.8Very high97.1Very high88 Ų8848.8 Ų48.833%0.33224%0.239SC..  trans-65.1138.6179.3-175.4-162.5179-127.6-3.5110.4P44 Y45 V46 V75 Q80 Y83P44-R77 HydrophobicContact CB-CB 4.03Å; P44-R77 HydrophobicContact CB-CG 4.15Å; Y45-R77 WeakPolarHBondContact O-CB 3.05Å; Y45-R77 PolarHBondContact O-N 3.24Å; V46-R77 HydrophobicContact CG2-CB 3.8Å; V46-R77 HydrophobicContact CG2-CG 4.42Å; V75-R77 PolarHBondContact O-N 2.9Å; R77-Q80 PolarHBondContact NE-O 2.94Å; R77-Q80 PolarHBondContact NH2-O 3.2Å; R77-Y83 HydrophobicContact CG-CG 4.25Å; R77-Y83 VanDerWaalsContact CZ-CE1 3.4Å
78T96.8Very high96.8Very high95 Ų9549.2 Ų49.258%0.58324%0.239SC*.SBendtrans-114.4-81.9169.154.70000109.8Q80T78-Q80 PolarHBondContact OG1-OE1 3.33Å
79Y94.9Very high96.5Very high197 Ų19748.3 Ų48.377%0.77323%0.234SC*.SBendtrans-115.6-1.7-174.656.9-96.1000113.7S81Y79-S81 PolarHBondContact O-N 2.95Å
80Q97.2Very high95.8Very high40 Ų4049.1 Ų49.119%0.18724%0.243CC..  trans-61.4132.2-175.9-57.689.2-16.600110.7P44 R77 T78 D82P44-Q80 HydrophobicContact CB-CB 4.04Å; P44-Q80 HydrophobicContact CB-CG 4.09Å; P44-Q80 HydrophobicContact CG-CB 3.7Å; P44-Q80 HydrophobicContact CG-CG 3.53Å; R77-Q80 PolarHBondContact NE-O 2.94Å; R77-Q80 PolarHBondContact NH2-O 3.2Å; T78-Q80 PolarHBondContact OG1-OE1 3.33Å; Q80-D82 VanDerWaalsContact C-N 3.3Å
81S95.6Very high95.4Very high87 Ų8750.2 Ų50.261%0.60825%0.254SS*.SBendtrans-68.3-34.6177.3600000111.9Y79 G101Y79-S81 PolarHBondContact O-N 2.95Å; S81-G101 CarbonylContact O-C 3.59Å; S81-G101 VanDerWaalsContact O-CA 3.31Å; S81-G101 WeakPolarHBondContact O-CA 3.21Å
82D96.8Very high95Very high31 Ų3151.3 Ų51.317%0.16626%0.261CS..SBendtrans-105.5125-177.4-57.9-8.1000108.9W38 Q80 R98 G101W38-D82 HydrophobicContact CZ3-CB 4.12Å; Q80-D82 VanDerWaalsContact C-N 3.3Å; D82-R98 HydrophobicContact CB-CG 4.42Å; D82-R98 IonicContact OD2-CZ 3.28Å; D82-R98 IonicContact OD2-NH1 2.71Å; D82-R98 PolarHBondContact OD2-NH1 3.4Å; D82-G101 WeakPolarHBondContact CA-O 3.18Å; D82-G101 PolarHBondContact OD1-N 3.49Å
83Y97.9Very high94.6Very high33 Ų3351.7 Ų51.713%0.12926%0.263CS..EExtended strand (participates in β ladder)trans-163.3158.2-175.168-82.3000111.7P44 V46 R77 G101 R102 Q103P44-Y83 CarbonylContact O-C 3.48Å; P44-Y83 VanDerWaalsContact O-CA 3.26Å; P44-Y83 WeakPolarHBondContact O-CA 3.33Å; P44-Y83 WeakPolarHBondContact O-CB 3.4Å; V46-Y83 HydrophobicContact CB-CD2 4.49Å; V46-Y83 HydrophobicContact CB-CE2 4.4Å; V46-Y83 HydrophobicContact CG2-CD2 3.96Å; V46-Y83 HydrophobicContact CG2-CE2 3.94Å; R77-Y83 HydrophobicContact CG-CG 4.25Å; R77-Y83 VanDerWaalsContact CZ-CE1 3.4Å; Y83-G101 PolarHBondContact N-O 3.05Å; Y83-G101 VanDerWaalsContact N-O 3.13Å; Y83-R102 HydrophobicContact CD1-CB 4.45Å; Y83-R102 HydrophobicContact CE1-CB 3.71Å; Y83-R102 HydrophobicContact CE1-CG 4.33Å; Y83-R102 HydrophobicContact CE2-CB 4.21Å; Y83-R102 HydrophobicContact CE2-CG 3.9Å; Y83-Q103 PolarHBondContact O-N 3.28Å
84L98Very high94.4Very high0 Ų048.1 Ų48.10%025%0.249CC..EExtended strand (participates in β ladder)trans-84.1128.5169-62.7-178.9000110.8W38 I43 P44 Y45 V46 F74 I86 Q103 L105 A124W38-L84 HydrophobicContact CH2-CD2 4.2Å; W38-L84 HydrophobicContact CH2-CG 4.28Å; W38-L84 HydrophobicContact CZ2-CD2 3.84Å; W38-L84 HydrophobicContact CZ2-CG 4.14Å; I43-L84 HydrophobicContact CG2-CD1 3.46Å; I43-L84 VanDerWaalsContact CG2-CD1 3.46Å; I43-L84 HydrophobicContact CG2-CG 3.71Å; P44-L84 PolarHBondContact O-N 3.48Å; Y45-L84 CarbonylContact C-O 3.48Å; Y45-L84 WeakPolarHBondContact CA-O 3.38Å; V46-L84 PolarHBondContact N-O 3.42Å; F74-L84 HydrophobicContact CE1-CD1 4.28Å; L84-I86 HydrophobicContact CB-CG1 4.25Å; L84-Q103 CarbonylContact C-O 3.51Å; L84-Q103 VanDerWaalsContact CA-O 3.27Å; L84-Q103 WeakPolarHBondContact CA-O 3.45Å; L84-Q103 HydrophobicContact CD2-CB 4.13Å; L84-Q103 HydrophobicContact CD2-CG 3.92Å; L84-L105 HydrophobicContact CD1-CD1 4.19Å; L84-A124 HydrophobicContact CD1-CB 3.71Å; L84-A124 HydrophobicContact CD2-CB 4.04Å; L84-A124 HydrophobicContact CG-CB 4.5Å
85Y97.9Very high94Very high51 Ų5147.9 Ų47.920%0.225%0.248CC..EExtended strand (participates in β ladder)trans-96.3110.4158176.1-93.9000108.2V46 I89 Q103 D104 L105V46-Y85 HydrophobicContact CB-CD2 4.36Å; V46-Y85 HydrophobicContact CG1-CD2 4.26Å; Y85-I89 HydrophobicContact CD1-CD1 4.31Å; Y85-I89 HydrophobicContact CE1-CD1 4.48Å; Y85-Q103 PolarHBondContact N-O 2.82Å; Y85-D104 WeakPolarHBondContact CD1-OD1 3.26Å; Y85-L105 PolarHBondContact O-N 3.22Å
86I98.1Very high93.6Very high0 Ų046.5 Ų46.50%024%0.24CC..EExtended strand (participates in β ladder)trans-95.3114.4178.9-60.4169.9000107.3Y45 V46 L47 G48 Y51 I59 M63 L84 L105 L107 L121Y45-I86 HydrophobicContact CD2-CD1 4.32Å; Y45-I86 HydrophobicContact CG-CD1 4.34Å; V46-I86 PolarHBondContact O-N 3.15Å; L47-I86 CarbonylContact C-O 3.46Å; L47-I86 HydrophobicContact CD2-CB 3.83Å; L47-I86 HydrophobicContact CD2-CD1 3.99Å; L47-I86 HydrophobicContact CD2-CG1 4.47Å; L47-I86 HydrophobicContact CD2-CG2 4.02Å; G48-I86 PolarHBondContact N-O 2.64Å; Y51-I86 HydrophobicContact CE2-CG2 4.25Å; Y51-I86 WeakPolarHBondContact CE2-O 3.37Å; I59-I86 HydrophobicContact CD1-CG2 4.48Å; M63-I86 HydrophobicContact CE-CD1 3.33Å; L84-I86 HydrophobicContact CB-CG1 4.25Å; I86-L105 VanDerWaalsContact CA-O 3.31Å; I86-L105 WeakPolarHBondContact CA-O 3.45Å; I86-L105 HydrophobicContact CG1-CB 4.24Å; I86-L105 HydrophobicContact CG1-CD2 4.45Å; I86-L105 HydrophobicContact CG2-CD2 4.26Å; I86-L107 HydrophobicContact CG2-CD1 3.69Å; I86-L107 HydrophobicContact CG2-CG 4.32Å; I86-L121 HydrophobicContact CD1-CD2 4.4Å
87G96.1Very high93.4Very high1 Ų142.3 Ų42.31%0.0121%0.213CC..EExtended strand (participates in β ladder)trans-154.9174.5-173.300000113.6Y51 I89 L105 S106 L107Y51-G87 WeakPolarHBondContact OH-CA 2.92Å; Y51-G87 PolarHBondContact OH-N 3.05Å; Y51-G87 PolarHBondContact OH-O 2.89Å; G87-I89 PolarHBondContact O-N 3.48Å; G87-L105 PolarHBondContact N-O 2.68Å; G87-S106 VanDerWaalsContact O-CA 3.3Å; G87-S106 WeakPolarHBondContact O-CA 2.76Å; G87-L107 PolarHBondContact O-N 3.27Å
88R90.1Very high93.2Very high51 Ų5140.7 Ų40.719%0.19221%0.207CC..  trans-81.9111.5168-59.6-177.4-175-76.6-2.3107.8F50 Y51 E55 D108F50-R88 PolarHBondContact O-NE 3.03Å; Y51-R88 HydrophobicContact CE1-CG 4Å; E55-R88 IonicContact OE1-CZ 2.64Å; E55-R88 IonicContact OE1-NH2 3.03Å; E55-R88 PolarHBondContact OE1-NH2 2.91Å; E55-R88 IonicContact OE2-NH2 2.89Å; E55-R88 PolarHBondContact OE2-NH2 2.85Å; R88-D108 IonicContact NH1-OD1 2.91Å
89I89Confident92.7Very high67 Ų6736.6 Ų36.634%0.34418%0.183SC..SBendtrans-124.7-69-176.5-53.2173.6000109.6Y85 G87 F93 D104 S106Y85-I89 HydrophobicContact CD1-CD1 4.31Å; Y85-I89 HydrophobicContact CE1-CD1 4.48Å; G87-I89 PolarHBondContact O-N 3.48Å; I89-F93 HydrophobicContact CB-CE1 4.21Å; I89-F93 HydrophobicContact CB-CZ 4.16Å; I89-F93 HydrophobicContact CD1-CZ 4.3Å; I89-F93 HydrophobicContact CG2-CE1 4.21Å; I89-F93 HydrophobicContact CG2-CZ 3.96Å; I89-D104 HydrophobicContact CD1-CB 3.49Å; I89-D104 VanDerWaalsContact CD1-CB 3.49Å; I89-S106 PolarHBondContact N-OG 3.14Å
90D82.4Confident92.4Very high75 Ų7527.8 Ų27.840%0.40115%0.153SC..SBendtrans-163.798.3178.4-177.414.8000109.8K6 F93 S106K6-D90 VanDerWaalsContact CE-O 3.31Å; K6-D90 WeakPolarHBondContact CE-O 3.2Å; K6-D90 PolarHBondContact NZ-O 3.2Å; D90-F93 HydrophobicContact CB-CE1 4.26Å; D90-F93 WeakPolarHBondContact O-CD1 3.29Å; D90-F93 WeakPolarHBondContact O-CE1 3.37Å; D90-S106 PolarHBondContact N-OG 3.41Å
91G86.3Confident92.3Very high23 Ų2327.2 Ų27.224%0.23716%0.157CC..SBendtrans60.4-150.3-177.100000113.7S106 D108G91-S106 CarbonylContact O-C 3.25Å; G91-S106 VanDerWaalsContact O-CB 3.31Å; G91-S106 WeakPolarHBondContact O-CB 3.47Å; G91-S106 PolarHBondContact O-OG 3.15Å; G91-D108 WeakPolarHBondContact O-CB 3.22Å; G91-D108 PolarHBondContact O-N 3.09Å
92C89Confident92.3Very high37 Ų3728.9 Ų28.925%0.2515%0.151CC..EExtended strand (participates in β ladder)trans-101.5126.5177.5-31.70000108.6K6 S106 C111 T116 E120K6-C92 PolarHBondContact NZ-O 3.4Å; C92-S106 WeakPolarHBondContact CA-O 3.3Å; C92-C111 WeakPolarHBondContact CA-SG 3.37Å; C92-C111 HydrophobicContact CB-CB 3.86Å; C92-C111 WeakPolarHBondContact CB-SG 3.27Å; C92-C111 PolarHBondContact N-SG 3.06Å; C92-C111 WeakPolarHBondContact SG-CB 3.37Å; C92-C111 CovalentContact SG-SG 2.03Å; C92-C111 PolarHBondContact SG-SG 3.24Å; C92-T116 HydrophobicContact CB-CG2 4.14Å; C92-E120 HydrophobicContact CB-CG 4.42Å; C92-E120 WeakPolarHBondContact CB-OE1 3.46Å
93F90.7Very high92.2Very high8 Ų827.9 Ų27.94%0.03515%0.145CC..EExtended strand (participates in β ladder)trans-166.6160.8169.768.6-97000114.2K6 D10 A12 I89 D90 D104 L105 S106 E120K6-F93 HydrophobicContact CD-CB 4.01Å; K6-F93 HydrophobicContact CD-CD1 4.29Å; K6-F93 HydrophobicContact CD-CG 4.45Å; D10-F93 CarbonylContact O-C 3.54Å; D10-F93 WeakPolarHBondContact O-CA 3.5Å; D10-F93 WeakPolarHBondContact O-CB 2.96Å; A12-F93 HydrophobicContact CB-CD2 3.65Å; A12-F93 HydrophobicContact CB-CE2 3.98Å; A12-F93 HydrophobicContact CB-CG 4.18Å; I89-F93 HydrophobicContact CB-CE1 4.21Å; I89-F93 HydrophobicContact CB-CZ 4.16Å; I89-F93 HydrophobicContact CD1-CZ 4.3Å; I89-F93 HydrophobicContact CG2-CE1 4.21Å; I89-F93 HydrophobicContact CG2-CZ 3.96Å; D90-F93 HydrophobicContact CB-CE1 4.26Å; D90-F93 WeakPolarHBondContact O-CD1 3.29Å; D90-F93 WeakPolarHBondContact O-CE1 3.37Å; F93-D104 HydrophobicContact CE2-CB 4.42Å; F93-L105 CarbonylContact O-C 3.47Å; F93-L105 WeakPolarHBondContact O-CA 2.9Å; F93-S106 PolarHBondContact N-O 3.48Å; F93-S106 VanDerWaalsContact N-O 3.15Å; F93-S106 PolarHBondContact O-N 3.21Å; F93-E120 WeakPolarHBondContact CA-OE2 3.33Å; F93-E120 PolarHBondContact N-OE1 3.17Å
94S92.6Very high92.1Very high0 Ų029.1 Ų29.10%015%0.153CC..EExtended strand (participates in β ladder)trans-146.4160.3167.2-178.40000111.7D10 I11 A12 E120 A124D10-S94 PolarHBondContact O-N 2.75Å; I11-S94 VanDerWaalsContact CA-O 3.26Å; I11-S94 WeakPolarHBondContact CA-O 3.22Å; I11-S94 WeakPolarHBondContact CG2-O 3.29Å; A12-S94 PolarHBondContact N-O 3.1Å; A12-S94 CarbonylContact O-C 3.6Å; S94-E120 VanDerWaalsContact CB-O 3.31Å; S94-E120 WeakPolarHBondContact CB-O 3.29Å; S94-E120 PolarHBondContact N-OE2 2.82Å; S94-E120 PolarHBondContact OG-O 3.14Å; S94-A124 WeakPolarHBondContact OG-CB 3.03Å; S94-A124 PolarHBondContact OG-N 2.94Å
95D90.7Very high92Very high2 Ų229.1 Ų29.11%0.01115%0.153CC..  trans-78.8160.5161.4-153.612000110.1A12 G13 K14 A15 A16 Q103 H123 A124A12-D95 WeakPolarHBondContact O-CA 3.25Å; A12-D95 WeakPolarHBondContact O-CB 3.25Å; A12-D95 PolarHBondContact O-N 2.8Å; A12-D95 VanDerWaalsContact O-N 3.09Å; G13-D95 VanDerWaalsContact CA-CG 3.48Å; K14-D95 WeakPolarHBondContact CA-OD2 3.15Å; K14-D95 PolarHBondContact N-OD2 2.7Å; A15-D95 WeakPolarHBondContact CA-OD1 3.27Å; A15-D95 WeakPolarHBondContact CB-OD1 3.4Å; A15-D95 VanDerWaalsContact N-CG 3.34Å; A15-D95 PolarHBondContact N-OD1 3.28Å; A15-D95 PolarHBondContact N-OD2 3.36Å; A16-D95 PolarHBondContact N-OD1 2.93Å; A16-D95 VanDerWaalsContact N-OD1 3.15Å; D95-Q103 HydrophobicContact CB-CG 3.87Å; D95-H123 CarbonylContact O-C 3.55Å; D95-A124 WeakPolarHBondContact O-CA 3.44Å; D95-A124 PolarHBondContact O-N 3.01Å
96V90.9Very high91.9Very high2 Ų226.7 Ų26.71%0.01214%0.144CC..SBendtrans-91.5117.2177.5179.80000111.7I11 A15 V31 H123 W128I11-V96 HydrophobicContact CD1-CG2 3.89Å; I11-V96 HydrophobicContact CG1-CG2 4.44Å; I11-V96 HydrophobicContact CG2-CG2 3.72Å; A15-V96 HydrophobicContact CB-CB 4.3Å; A15-V96 WeakPolarHBondContact CB-O 3.44Å; V31-V96 HydrophobicContact CG1-CG1 3.77Å; V96-H123 CarbonylContact C-O 3.52Å; V96-H123 VanDerWaalsContact CA-O 3.29Å; V96-H123 WeakPolarHBondContact CA-O 3.4Å; V96-H123 HydrophobicContact CG2-CB 4.34Å; V96-W128 HydrophobicContact CB-CD2 4.16Å; V96-W128 HydrophobicContact CB-CE3 4.31Å; V96-W128 HydrophobicContact CB-CH2 4.04Å; V96-W128 HydrophobicContact CB-CZ2 3.86Å; V96-W128 HydrophobicContact CB-CZ3 4.27Å; V96-W128 HydrophobicContact CG1-CD2 3.99Å; V96-W128 HydrophobicContact CG1-CG 4.25Å; V96-W128 HydrophobicContact CG1-CZ2 4.09Å; V96-W128 HydrophobicContact CG2-CD2 3.78Å; V96-W128 HydrophobicContact CG2-CE3 3.58Å; V96-W128 HydrophobicContact CG2-CG 4.49Å; V96-W128 HydrophobicContact CG2-CH2 4Å; V96-W128 HydrophobicContact CG2-CZ2 4.17Å; V96-W128 HydrophobicContact CG2-CZ3 3.71Å
97G93Very high91.6Very high0 Ų026.7 Ų26.70%014%0.144CC..SBendtrans73.3-154.9179.700000112.4D36 Q103 H123 A124D36-G97 CarbonylContact O-C 3.4Å; D36-G97 WeakPolarHBondContact O-CA 3.3Å; G97-Q103 PolarHBondContact O-NE2 2.69Å; G97-Q103 PolarHBondContact O-OE1 3.27Å; G97-H123 PolarHBondContact N-O 3.05Å; G97-A124 CarbonylContact C-O 3.47Å; G97-A124 VanDerWaalsContact CA-O 3.22Å; G97-A124 WeakPolarHBondContact CA-O 3.25Å; G97-A124 PolarHBondContact N-O 2.93Å
98R93.3Very high91.2Very high54 Ų5428.3 Ų28.320%0.20415%0.153CC..  trans-90.1104.6178.5-172.7178.363.692.50.2111.2K35 D36 K37 W38 D82K35-R98 VanDerWaalsContact O-CZ 3.23Å; K35-R98 PolarHBondContact O-NE 3.38Å; K35-R98 PolarHBondContact O-NH2 3.41Å; D36-R98 PolarHBondContact O-N 2.82Å; K37-R98 PolarHBondContact O-NE 3.13Å; W38-R98 HydrophobicContact CD2-CB 3.85Å; W38-R98 HydrophobicContact CD2-CG 3.99Å; W38-R98 HydrophobicContact CE3-CB 4.33Å; W38-R98 HydrophobicContact CE3-CG 3.93Å; W38-R98 HydrophobicContact CG-CB 4.14Å; W38-R98 HydrophobicContact CH2-CG 4.15Å; W38-R98 HydrophobicContact CZ2-CB 4.18Å; W38-R98 HydrophobicContact CZ2-CG 4.2Å; W38-R98 HydrophobicContact CZ3-CG 4.02Å; D82-R98 HydrophobicContact CB-CG 4.42Å; D82-R98 IonicContact OD2-CZ 3.28Å; D82-R98 IonicContact OD2-NH1 2.71Å; D82-R98 PolarHBondContact OD2-NH1 3.4Å
99G86Confident90.9Very high9 Ų934.4 Ų34.49%0.09318%0.177CC..  trans-78-20.517300000114.5K14K14-G99 WeakPolarHBondContact CD-O 3.5Å; K14-G99 PolarHBondContact NZ-O 3.24Å
100G89.4Confident90.5Very high13 Ų1334.7 Ų34.713%0.13420%0.196CC..SBendtrans85.1151.6-17700000113.6K14K14-G100 PolarHBondContact NZ-O 3.34Å
101G94.4Very high90.8Very high27 Ų2731.2 Ų31.228%0.27818%0.178SC..SBendtrans65.7-161.2-168.400000112.6S81 D82 Y83 Q103S81-G101 CarbonylContact O-C 3.59Å; S81-G101 VanDerWaalsContact O-CA 3.31Å; S81-G101 WeakPolarHBondContact O-CA 3.21Å; D82-G101 WeakPolarHBondContact CA-O 3.18Å; D82-G101 PolarHBondContact OD1-N 3.49Å; Y83-G101 PolarHBondContact N-O 3.05Å; Y83-G101 VanDerWaalsContact N-O 3.13Å; G101-Q103 PolarHBondContact O-N 3.33Å
102R95.3Very high91Very high123 Ų12331.6 Ų31.646%0.46417%0.174SC..EExtended strand (participates in β ladder)trans-64124.7165.7178.5-180161.8157.5-7.3109.4Y83 D104Y83-R102 HydrophobicContact CD1-CB 4.45Å; Y83-R102 HydrophobicContact CE1-CB 3.71Å; Y83-R102 HydrophobicContact CE1-CG 4.33Å; Y83-R102 HydrophobicContact CE2-CB 4.21Å; Y83-R102 HydrophobicContact CE2-CG 3.9Å; R102-D104 IonicContact CZ-OD1 3.87Å; R102-D104 IonicContact NE-OD1 2.86Å; R102-D104 PolarHBondContact NE-OD1 2.84Å; R102-D104 IonicContact NH2-OD1 3.29Å; R102-D104 PolarHBondContact NH2-OD1 2.93Å; R102-D104 IonicContact NH2-OD2 2.83Å
103Q95.1Very high91.1Very high10 Ų1032.3 Ų32.35%0.04718%0.175CC..EExtended strand (participates in β ladder)trans-116.6125.2172.3174.2175-45.400108.5Y83 L84 Y85 D95 G97 G101Y83-Q103 PolarHBondContact O-N 3.28Å; L84-Q103 CarbonylContact C-O 3.51Å; L84-Q103 VanDerWaalsContact CA-O 3.27Å; L84-Q103 WeakPolarHBondContact CA-O 3.45Å; L84-Q103 HydrophobicContact CD2-CB 4.13Å; L84-Q103 HydrophobicContact CD2-CG 3.92Å; Y85-Q103 PolarHBondContact N-O 2.82Å; D95-Q103 HydrophobicContact CB-CG 3.87Å; G97-Q103 PolarHBondContact O-NE2 2.69Å; G97-Q103 PolarHBondContact O-OE1 3.27Å; G101-Q103 PolarHBondContact O-N 3.33Å
104D95.1Very high91.3Very high58 Ų5834.1 Ų34.131%0.3118%0.182SC..EExtended strand (participates in β ladder)trans-82.6138.4-179.1-74.4-24.5000110.6Y85 I89 F93 R102Y85-D104 WeakPolarHBondContact CD1-OD1 3.26Å; I89-D104 HydrophobicContact CD1-CB 3.49Å; I89-D104 VanDerWaalsContact CD1-CB 3.49Å; F93-D104 HydrophobicContact CE2-CB 4.42Å; R102-D104 IonicContact CZ-OD1 3.87Å; R102-D104 IonicContact NE-OD1 2.86Å; R102-D104 PolarHBondContact NE-OD1 2.84Å; R102-D104 IonicContact NH2-OD1 3.29Å; R102-D104 PolarHBondContact NH2-OD1 2.93Å; R102-D104 IonicContact NH2-OD2 2.83Å
105L97Very high91.3Very high0 Ų035.6 Ų35.60%019%0.191CC..EExtended strand (participates in β ladder)trans-126.3116.7167.9-173.5163.2000106.8L84 Y85 I86 G87 F93 L107 E120 L121 A124L84-L105 HydrophobicContact CD1-CD1 4.19Å; Y85-L105 PolarHBondContact O-N 3.22Å; I86-L105 VanDerWaalsContact CA-O 3.31Å; I86-L105 WeakPolarHBondContact CA-O 3.45Å; I86-L105 HydrophobicContact CG1-CB 4.24Å; I86-L105 HydrophobicContact CG1-CD2 4.45Å; I86-L105 HydrophobicContact CG2-CD2 4.26Å; G87-L105 PolarHBondContact N-O 2.68Å; F93-L105 CarbonylContact O-C 3.47Å; F93-L105 WeakPolarHBondContact O-CA 2.9Å; L105-L107 HydrophobicContact CD2-CD1 3.99Å; L105-L107 HydrophobicContact CD2-CD2 3.88Å; L105-L107 HydrophobicContact CD2-CG 3.54Å; L105-E120 HydrophobicContact CD1-CB 4.44Å; L105-E120 HydrophobicContact CD2-CB 4.14Å; L105-E120 HydrophobicContact CG-CB 4.39Å; L105-L121 HydrophobicContact CD1-CD2 3.81Å; L105-A124 HydrophobicContact CD1-CB 4.15Å
106S95Very high91.4Very high0 Ų037.1 Ų37.10%020%0.2CC..EExtended strand (participates in β ladder)trans-93.3123.2-176.7-1710000111G87 I89 D90 G91 C92 F93G87-S106 VanDerWaalsContact O-CA 3.3Å; G87-S106 WeakPolarHBondContact O-CA 2.76Å; I89-S106 PolarHBondContact N-OG 3.14Å; D90-S106 PolarHBondContact N-OG 3.41Å; G91-S106 CarbonylContact O-C 3.25Å; G91-S106 VanDerWaalsContact O-CB 3.31Å; G91-S106 WeakPolarHBondContact O-CB 3.47Å; G91-S106 PolarHBondContact O-OG 3.15Å; C92-S106 WeakPolarHBondContact CA-O 3.3Å; F93-S106 PolarHBondContact N-O 3.48Å; F93-S106 VanDerWaalsContact N-O 3.15Å; F93-S106 PolarHBondContact O-N 3.21Å
107L93Very high91.6Very high0 Ų037 Ų370%020%0.199CC..EExtended strand (participates in β ladder)trans-124.679.6166.7-59.7170.6000107.8Y51 I59 I86 G87 L105 C111 L112 I117 E120Y51-L107 WeakPolarHBondContact CE1-O 3.07Å; Y51-L107 PolarHBondContact OH-O 3.26Å; I59-L107 HydrophobicContact CD1-CD1 4.28Å; I59-L107 HydrophobicContact CG1-CD1 4.12Å; I86-L107 HydrophobicContact CG2-CD1 3.69Å; I86-L107 HydrophobicContact CG2-CG 4.32Å; G87-L107 PolarHBondContact O-N 3.27Å; L105-L107 HydrophobicContact CD2-CD1 3.99Å; L105-L107 HydrophobicContact CD2-CD2 3.88Å; L105-L107 HydrophobicContact CD2-CG 3.54Å; L107-C111 HydrophobicContact CB-CB 4.34Å; L107-C111 HydrophobicContact CD2-CB 4.23Å; L107-L112 HydrophobicContact CB-CD2 4Å; L107-L112 HydrophobicContact CD1-CD2 4.42Å; L107-I117 HydrophobicContact CD1-CD1 4.4Å; L107-I117 HydrophobicContact CD1-CG1 3.84Å; L107-I117 HydrophobicContact CD1-CG2 4.18Å; L107-I117 HydrophobicContact CD2-CG1 4Å; L107-E120 HydrophobicContact CD2-CB 4.19Å; L107-E120 HydrophobicContact CD2-CG 4.01Å
108D88.1Confident91.9Very high36 Ų3637 Ų3719%0.19320%0.199CC..  trans-78.1-174.8-179.8-155.70.4000112.3R88 G91 G110 C111R88-D108 IonicContact NH1-OD1 2.91Å; G91-D108 WeakPolarHBondContact O-CB 3.22Å; G91-D108 PolarHBondContact O-N 3.09Å; D108-G110 PolarHBondContact O-N 3.41Å; D108-C111 WeakPolarHBondContact O-CB 3.39Å; D108-C111 PolarHBondContact O-N 2.76Å
109Y82.7Confident92Very high178 Ų17835.7 Ų35.770%0.69820%0.195SC*.THydrogen-bonded Turntrans-53.3126.7170.4-63.2-76000110.5
110G81.3Confident92.6Very high73 Ų7335.4 Ų35.475%0.75319%0.191SC*.THydrogen-bonded Turntrans94.2-8.2-176.500000115.4D108D108-G110 PolarHBondContact O-N 3.41Å
111C89.1Confident93Very high2 Ų234.8 Ų34.81%0.01419%0.185CC..  trans-105.34.6179.1-49.30000113.7C92 L107 D108 D113 T116C92-C111 WeakPolarHBondContact CA-SG 3.37Å; C92-C111 HydrophobicContact CB-CB 3.86Å; C92-C111 WeakPolarHBondContact CB-SG 3.27Å; C92-C111 PolarHBondContact N-SG 3.06Å; C92-C111 WeakPolarHBondContact SG-CB 3.37Å; C92-C111 CovalentContact SG-SG 2.03Å; C92-C111 PolarHBondContact SG-SG 3.24Å; L107-C111 HydrophobicContact CB-CB 4.34Å; L107-C111 HydrophobicContact CD2-CB 4.23Å; D108-C111 WeakPolarHBondContact O-CB 3.39Å; D108-C111 PolarHBondContact O-N 2.76Å; C111-D113 VanDerWaalsContact C-N 3.32Å; C111-D113 PolarHBondContact O-N 3.5Å; C111-T116 HydrophobicContact CB-CG2 4.02Å
112L90.3Very high93.1Very high31 Ų3133.5 Ų33.516%0.16217%0.172CC..  trans-9736.6-170-71.8165.1000113.2Y51 E55 I59 L107 I117Y51-L112 HydrophobicContact CD1-CD1 4.08Å; Y51-L112 HydrophobicContact CD1-CD2 4.32Å; Y51-L112 HydrophobicContact CE1-CD1 3.97Å; Y51-L112 HydrophobicContact CE1-CD2 3.94Å; E55-L112 HydrophobicContact CB-CD1 4.03Å; E55-L112 HydrophobicContact CB-CD2 4.4Å; E55-L112 HydrophobicContact CG-CD1 3.68Å; E55-L112 VanDerWaalsContact OE1-CD1 3.26Å; E55-L112 WeakPolarHBondContact OE1-CD1 3.42Å; I59-L112 HydrophobicContact CD1-CD2 3.99Å; I59-L112 HydrophobicContact CG1-CD2 4.06Å; L107-L112 HydrophobicContact CB-CD2 4Å; L107-L112 HydrophobicContact CD1-CD2 4.42Å; L112-I117 HydrophobicContact CD2-CD1 4.25Å
113D89.7Confident93.2Very high52 Ų5227.7 Ų27.728%0.27815%0.15SC..SBendtrans-100.9160.8166.157.8-82.1000111.2C111 D115 T116 I117C111-D113 VanDerWaalsContact C-N 3.32Å; C111-D113 PolarHBondContact O-N 3.5Å; D113-D115 PolarHBondContact O-N 3.09Å; D113-D115 VanDerWaalsContact OD2-CG 3.31Å; D113-D115 VanDerWaalsContact OD2-OD1 3.05Å; D113-T116 VanDerWaalsContact CG-OG1 3.22Å; D113-T116 PolarHBondContact OD1-OG1 2.99Å; D113-T116 VanDerWaalsContact OD1-OG1 3.07Å; D113-T116 WeakPolarHBondContact OD2-CB 3.21Å; D113-T116 PolarHBondContact OD2-N 3.26Å; D113-T116 PolarHBondContact OD2-OG1 3.32Å; D113-I117 WeakPolarHBondContact O-CD1 3.01Å; D113-I117 WeakPolarHBondContact O-CG1 3.41Å; D113-I117 PolarHBondContact O-N 3.16Å; D113-I117 VanDerWaalsContact O-N 3.17Å
114Y95.4Very high93.2Very high46 Ų4627.2 Ų27.218%0.1815%0.148CC..Hα-helixtrans-62.4-46.2-170.3168.6-92.8000112.4R61 S62 A65 R69 I117 I118 K206 D207R61-Y114 HydrophobicContact CG-CD2 4.41Å; S62-Y114 WeakPolarHBondContact OG-CD2 3.4Å; S62-Y114 PolarHBondContact OG-O 3.45Å; A65-Y114 HydrophobicContact CB-CE2 3.97Å; A65-Y114 WeakPolarHBondContact CB-OH 3.04Å; R69-Y114 PolarHBondContact NH1-OH 3.07Å; Y114-I117 PolarHBondContact O-N 3.41Å; Y114-I118 HydrophobicContact CD1-CG1 4.18Å; Y114-I118 HydrophobicContact CD2-CG1 4.37Å; Y114-I118 HydrophobicContact CE1-CD1 4.01Å; Y114-I118 HydrophobicContact CE1-CG1 3.82Å; Y114-I118 HydrophobicContact CE2-CD1 3.84Å; Y114-I118 HydrophobicContact CE2-CG1 4.05Å; Y114-I118 HydrophobicContact CG-CG1 4.45Å; Y114-I118 VanDerWaalsContact CZ-CD1 3.49Å; Y114-I118 WeakPolarHBondContact O-CG1 3.41Å; Y114-I118 PolarHBondContact O-N 3.39Å; Y114-I118 WeakPolarHBondContact OH-CD1 2.99Å; Y114-K206 WeakPolarHBondContact CD1-O 3.4Å; Y114-K206 WeakPolarHBondContact CE1-O 3.17Å; Y114-D207 HydrophobicContact CE1-CB 4.17Å; Y114-D207 VanDerWaalsContact OH-CG 3.26Å; Y114-D207 PolarHBondContact OH-OD1 3.31Å; Y114-D207 PolarHBondContact OH-OD2 3.11Å
115D93.2Very high93.3Very high32 Ų3224.4 Ų24.417%0.17113%0.133CC..Hα-helixtrans-69.3-44.8-175.540.7-51.5000112.5D113 I117 I118 H119 I175 K206D113-D115 PolarHBondContact O-N 3.09Å; D113-D115 VanDerWaalsContact OD2-CG 3.31Å; D113-D115 VanDerWaalsContact OD2-OD1 3.05Å; D115-I117 VanDerWaalsContact C-N 3.32Å; D115-I117 PolarHBondContact O-N 3.16Å; D115-I118 PolarHBondContact O-N 3.05Å; D115-H119 WeakPolarHBondContact O-CB 3.35Å; D115-H119 PolarHBondContact O-N 3.07Å; D115-I175 HydrophobicContact CB-CD1 4.18Å; D115-K206 HydrophobicContact CB-CD 4.29Å; D115-K206 WeakPolarHBondContact OD2-CD 3.32Å; D115-K206 IonicContact OD2-NZ 4Å; D115-K206 PolarHBondContact OD2-NZ 2.91Å
116T91.4Very high93.2Very high34 Ų3424.4 Ų24.421%0.20913%0.133CC..Hα-helixtrans-60.2-44.2174.2-57.80000111C92 C111 D113 I118 H119 E120C92-T116 HydrophobicContact CB-CG2 4.14Å; C111-T116 HydrophobicContact CB-CG2 4.02Å; D113-T116 VanDerWaalsContact CG-OG1 3.22Å; D113-T116 PolarHBondContact OD1-OG1 2.99Å; D113-T116 VanDerWaalsContact OD1-OG1 3.07Å; D113-T116 WeakPolarHBondContact OD2-CB 3.21Å; D113-T116 PolarHBondContact OD2-N 3.26Å; D113-T116 PolarHBondContact OD2-OG1 3.32Å; T116-I118 VanDerWaalsContact C-N 3.34Å; T116-I118 PolarHBondContact O-N 3.26Å; T116-H119 WeakPolarHBondContact O-CB 3.3Å; T116-H119 PolarHBondContact O-N 3.17Å; T116-E120 HydrophobicContact CG2-CG 4.38Å; T116-E120 WeakPolarHBondContact O-CG 3.43Å; T116-E120 PolarHBondContact O-N 2.79Å
117I96.9Very high93.1Very high0 Ų024.4 Ų24.40%013%0.133CC..Hα-helixtrans-64.1-40.7177.6-62.5167.3000111.1V58 I59 L107 L112 D113 Y114 D115 H119 L121V58-I117 HydrophobicContact CB-CD1 4.34Å; V58-I117 HydrophobicContact CG1-CD1 3.77Å; I59-I117 HydrophobicContact CG1-CD1 3.92Å; L107-I117 HydrophobicContact CD1-CD1 4.4Å; L107-I117 HydrophobicContact CD1-CG1 3.84Å; L107-I117 HydrophobicContact CD1-CG2 4.18Å; L107-I117 HydrophobicContact CD2-CG1 4Å; L112-I117 HydrophobicContact CD2-CD1 4.25Å; D113-I117 WeakPolarHBondContact O-CD1 3.01Å; D113-I117 WeakPolarHBondContact O-CG1 3.41Å; D113-I117 PolarHBondContact O-N 3.16Å; D113-I117 VanDerWaalsContact O-N 3.17Å; Y114-I117 PolarHBondContact O-N 3.41Å; D115-I117 VanDerWaalsContact C-N 3.32Å; D115-I117 PolarHBondContact O-N 3.16Å; I117-H119 VanDerWaalsContact C-N 3.31Å; I117-H119 PolarHBondContact O-N 3.19Å; I117-L121 HydrophobicContact CG2-CD1 3.73Å; I117-L121 HydrophobicContact CG2-CG 4.09Å; I117-L121 VanDerWaalsContact O-CB 3.27Å; I117-L121 WeakPolarHBondContact O-CB 3.37Å; I117-L121 WeakPolarHBondContact O-CG 3.2Å; I117-L121 PolarHBondContact O-N 2.96Å
118I97.8Very high92.9Very high0 Ų024.7 Ų24.70%013%0.134CC..Hα-helixtrans-58.9-46.5175.8-66-100.6000110A65 Y66 Y114 D115 T116 L121 M122 I175 F208A65-I118 HydrophobicContact CB-CD1 3.7Å; Y66-I118 HydrophobicContact CE2-CD1 4.26Å; Y66-I118 HydrophobicContact CE2-CG2 4.38Å; Y66-I118 PolarHBondContact OH-O 2.68Å; Y114-I118 HydrophobicContact CD1-CG1 4.18Å; Y114-I118 HydrophobicContact CD2-CG1 4.37Å; Y114-I118 HydrophobicContact CE1-CD1 4.01Å; Y114-I118 HydrophobicContact CE1-CG1 3.82Å; Y114-I118 HydrophobicContact CE2-CD1 3.84Å; Y114-I118 HydrophobicContact CE2-CG1 4.05Å; Y114-I118 HydrophobicContact CG-CG1 4.45Å; Y114-I118 VanDerWaalsContact CZ-CD1 3.49Å; Y114-I118 WeakPolarHBondContact O-CG1 3.41Å; Y114-I118 PolarHBondContact O-N 3.39Å; Y114-I118 WeakPolarHBondContact OH-CD1 2.99Å; D115-I118 PolarHBondContact O-N 3.05Å; T116-I118 VanDerWaalsContact C-N 3.34Å; T116-I118 PolarHBondContact O-N 3.26Å; I118-L121 PolarHBondContact O-N 3.13Å; I118-M122 WeakPolarHBondContact O-CB 3.17Å; I118-M122 PolarHBondContact O-N 3.34Å; I118-I175 HydrophobicContact CB-CD1 3.94Å; I118-I175 HydrophobicContact CG2-CD1 3.7Å; I118-I175 HydrophobicContact CG2-CG2 4.37Å; I118-F208 HydrophobicContact CD1-CD2 4.22Å; I118-F208 HydrophobicContact CD1-CE2 3.43Å; I118-F208 VanDerWaalsContact CD1-CE2 3.43Å; I118-F208 HydrophobicContact CD1-CZ 3.67Å; I118-F208 HydrophobicContact CG2-CD1 3.85Å; I118-F208 HydrophobicContact CG2-CD2 4.29Å; I118-F208 HydrophobicContact CG2-CE1 3.38Å; I118-F208 HydrophobicContact CG2-CE2 3.9Å; I118-F208 HydrophobicContact CG2-CG 4.29Å; I118-F208 HydrophobicContact CG2-CZ 3.42Å; I118-F208 VanDerWaalsContact CG2-CZ 3.42Å
119H96.4Very high93.2Very high25 Ų2523 Ų2312%0.11613%0.125CC..Hα-helixtrans-58-53.5179.5-173.7107.4000111.9D10 D115 T116 I117 L121 M122 H123 H129 I175D10-H119 IonicContact OD2-CD2 2.69Å; D10-H119 IonicContact OD2-NE2 3.71Å; D10-H119 PolarHBondContact OD2-NE2 2.84Å; D115-H119 WeakPolarHBondContact O-CB 3.35Å; D115-H119 PolarHBondContact O-N 3.07Å; T116-H119 WeakPolarHBondContact O-CB 3.3Å; T116-H119 PolarHBondContact O-N 3.17Å; I117-H119 VanDerWaalsContact C-N 3.31Å; I117-H119 PolarHBondContact O-N 3.19Å; H119-L121 VanDerWaalsContact C-N 3.34Å; H119-L121 PolarHBondContact O-N 3.14Å; H119-M122 WeakPolarHBondContact O-CA 3.41Å; H119-M122 VanDerWaalsContact O-CB 3.3Å; H119-M122 WeakPolarHBondContact O-CB 3.2Å; H119-M122 PolarHBondContact O-N 3.01Å; H119-H123 AromaticContact CD2-CD2 3.73Å; H119-H123 AromaticContact CD2-NE2 3.51Å; H119-H123 AromaticContact NE2-CD2 3.86Å; H119-H123 AromaticContact NE2-CE1 3.87Å; H119-H123 AromaticContact NE2-NE2 3.13Å; H119-H123 PolarHBondContact NE2-NE2 3.44Å; H119-H123 VanDerWaalsContact NE2-NE2 3.13Å; H119-H123 PolarHBondContact O-N 2.81Å; H119-H123 VanDerWaalsContact O-N 3.07Å; H119-H129 AromaticContact CE1-CD2 3.71Å; H119-H129 AromaticContact CE1-NE2 3.65Å; H119-H129 AromaticContact NE2-CD2 3.73Å; H119-H129 AromaticContact NE2-NE2 3.28Å; H119-H129 PolarHBondContact NE2-NE2 3.06Å; H119-I175 HydrophobicContact CB-CG1 4.43Å; H119-I175 PolarHBondContact CE1-O 2.79Å; H119-I175 PolarHBondContact ND1-O 2.65Å
120E97.3Very high93.8Very high3 Ų314.5 Ų14.51%0.0149%0.092CC..Hα-helixtrans-64.6-38.6-179.4-63.2-62.9177.300112.3C92 F93 S94 L105 L107 T116 M122 H123 A124C92-E120 HydrophobicContact CB-CG 4.42Å; C92-E120 WeakPolarHBondContact CB-OE1 3.46Å; F93-E120 WeakPolarHBondContact CA-OE2 3.33Å; F93-E120 PolarHBondContact N-OE1 3.17Å; S94-E120 VanDerWaalsContact CB-O 3.31Å; S94-E120 WeakPolarHBondContact CB-O 3.29Å; S94-E120 PolarHBondContact N-OE2 2.82Å; S94-E120 PolarHBondContact OG-O 3.14Å; L105-E120 HydrophobicContact CD1-CB 4.44Å; L105-E120 HydrophobicContact CD2-CB 4.14Å; L105-E120 HydrophobicContact CG-CB 4.39Å; L107-E120 HydrophobicContact CD2-CB 4.19Å; L107-E120 HydrophobicContact CD2-CG 4.01Å; T116-E120 HydrophobicContact CG2-CG 4.38Å; T116-E120 WeakPolarHBondContact O-CG 3.43Å; T116-E120 PolarHBondContact O-N 2.79Å; E120-M122 PolarHBondContact O-N 2.71Å; E120-H123 WeakPolarHBondContact O-CB 3.1Å; E120-H123 PolarHBondContact O-N 2.91Å; E120-H123 IonicContact OE2-CD2 3.77Å; E120-A124 PolarHBondContact O-N 3.14Å
121L98.2Very high94.3Very high1 Ų111 Ų111%0.0056%0.056CC..Hα-helixtrans-64.4-30.8171.7-69.4177.2000111.3M63 Y66 F74 I86 L105 I117 I118 H119 A124 V125M63-L121 HydrophobicContact CG-CD1 4Å; Y66-L121 HydrophobicContact CD2-CD1 4.29Å; Y66-L121 HydrophobicContact CE2-CB 3.6Å; Y66-L121 HydrophobicContact CE2-CD1 3.94Å; Y66-L121 HydrophobicContact CE2-CG 4.45Å; F74-L121 HydrophobicContact CD1-CD2 4.31Å; F74-L121 HydrophobicContact CE1-CD2 3.66Å; F74-L121 HydrophobicContact CE1-CG 4.49Å; F74-L121 HydrophobicContact CE2-CD1 4.28Å; F74-L121 HydrophobicContact CZ-CB 3.92Å; F74-L121 HydrophobicContact CZ-CD1 4.19Å; F74-L121 HydrophobicContact CZ-CD2 3.86Å; F74-L121 HydrophobicContact CZ-CG 4.21Å; I86-L121 HydrophobicContact CD1-CD2 4.4Å; L105-L121 HydrophobicContact CD1-CD2 3.81Å; I117-L121 HydrophobicContact CG2-CD1 3.73Å; I117-L121 HydrophobicContact CG2-CG 4.09Å; I117-L121 VanDerWaalsContact O-CB 3.27Å; I117-L121 WeakPolarHBondContact O-CB 3.37Å; I117-L121 WeakPolarHBondContact O-CG 3.2Å; I117-L121 PolarHBondContact O-N 2.96Å; I118-L121 PolarHBondContact O-N 3.13Å; H119-L121 VanDerWaalsContact C-N 3.34Å; H119-L121 PolarHBondContact O-N 3.14Å; L121-A124 WeakPolarHBondContact O-CB 3.4Å; L121-A124 PolarHBondContact O-N 3.18Å; L121-V125 WeakPolarHBondContact O-CB 3.43Å; L121-V125 WeakPolarHBondContact O-CG2 3.31Å; L121-V125 PolarHBondContact O-N 3.2Å
122M97.8Very high94.4Very high0 Ų011 Ų110%06%0.055CC..Hα-helixtrans-72.9-34.1-179.4-159.5168.8158.900111.2Y66 I118 H119 E120 V125 G126 F127 I175 M176 F208 D212 I216Y66-M122 WeakPolarHBondContact OH-CA 3.3Å; Y66-M122 WeakPolarHBondContact OH-CB 3.29Å; Y66-M122 PolarHBondContact OH-N 2.86Å; I118-M122 WeakPolarHBondContact O-CB 3.17Å; I118-M122 PolarHBondContact O-N 3.34Å; H119-M122 WeakPolarHBondContact O-CA 3.41Å; H119-M122 VanDerWaalsContact O-CB 3.3Å; H119-M122 WeakPolarHBondContact O-CB 3.2Å; H119-M122 PolarHBondContact O-N 3.01Å; E120-M122 PolarHBondContact O-N 2.71Å; M122-V125 WeakPolarHBondContact O-CB 3.15Å; M122-V125 PolarHBondContact O-N 3.48Å; M122-G126 PolarHBondContact O-N 2.71Å; M122-F127 HydrophobicContact CE-CB 3.97Å; M122-F127 HydrophobicContact CE-CD1 4.03Å; M122-F127 HydrophobicContact CE-CD2 3.77Å; M122-F127 HydrophobicContact CE-CE2 4.33Å; M122-F127 HydrophobicContact CE-CG 3.61Å; M122-F127 HydrophobicContact CG-CB 4.02Å; M122-F127 HydrophobicContact CG-CD2 3.86Å; M122-F127 HydrophobicContact CG-CG 4.18Å; M122-F127 PolarHBondContact O-N 2.72Å; M122-I175 HydrophobicContact SD-CG2 3.8Å; M122-M176 HydrophobicContact CB-CE 4.33Å; M122-M176 HydrophobicContact CB-SD 3.54Å; M122-M176 VanDerWaalsContact CB-SD 3.54Å; M122-M176 HydrophobicContact CE-CG 3.69Å; M122-M176 HydrophobicContact CG-CG 4.16Å; M122-M176 HydrophobicContact CG-SD 3.83Å; M122-M176 HydrophobicContact SD-CG 3.49Å; M122-M176 WeakPolarHBondContact SD-CG 3.38Å; M122-M176 HydrophobicContact SD-SD 3.66Å; M122-M176 VanDerWaalsContact SD-SD 3.66Å; M122-F208 HydrophobicContact SD-CD1 4.2Å; M122-F208 HydrophobicContact SD-CE1 4.24Å; M122-D212 HydrophobicContact CE-CB 3.83Å; M122-D212 HydrophobicContact SD-CB 4.24Å; M122-I216 HydrophobicContact CE-CD1 4.18Å; M122-I216 HydrophobicContact CE-CG1 4.25Å; M122-I216 HydrophobicContact CG-CD1 4.4Å; M122-I216 HydrophobicContact SD-CD1 4.24Å
123H95.6Very high94.2Very high0 Ų09.6 Ų9.60%05%0.048CC..Hα-helixtrans-56.2-54.3164.4-74.4-44.4000111.1D10 D95 V96 G97 H119 E120 V125 G126 F127 H129 M176D10-H123 IonicContact OD1-NE2 3.67Å; D10-H123 PolarHBondContact OD1-NE2 3.2Å; D10-H123 IonicContact OD2-NE2 3.18Å; D95-H123 CarbonylContact O-C 3.55Å; V96-H123 CarbonylContact C-O 3.52Å; V96-H123 VanDerWaalsContact CA-O 3.29Å; V96-H123 WeakPolarHBondContact CA-O 3.4Å; V96-H123 HydrophobicContact CG2-CB 4.34Å; G97-H123 PolarHBondContact N-O 3.05Å; H119-H123 AromaticContact CD2-CD2 3.73Å; H119-H123 AromaticContact CD2-NE2 3.51Å; H119-H123 AromaticContact NE2-CD2 3.86Å; H119-H123 AromaticContact NE2-CE1 3.87Å; H119-H123 AromaticContact NE2-NE2 3.13Å; H119-H123 PolarHBondContact NE2-NE2 3.44Å; H119-H123 VanDerWaalsContact NE2-NE2 3.13Å; H119-H123 PolarHBondContact O-N 2.81Å; H119-H123 VanDerWaalsContact O-N 3.07Å; E120-H123 WeakPolarHBondContact O-CB 3.1Å; E120-H123 PolarHBondContact O-N 2.91Å; E120-H123 IonicContact OE2-CD2 3.77Å; H123-V125 VanDerWaalsContact C-N 3.26Å; H123-V125 PolarHBondContact O-N 2.88Å; H123-G126 VanDerWaalsContact O-CA 3.25Å; H123-G126 WeakPolarHBondContact O-CA 3.43Å; H123-G126 PolarHBondContact O-N 2.86Å; H123-F127 WeakPolarHBondContact CA-O 3.5Å; H123-F127 PolarHBondContact ND1-O 3.17Å; H123-H129 AromaticContact CE1-CD2 3.99Å; H123-H129 AromaticContact CE1-CE1 3.74Å; H123-H129 AromaticContact CE1-NE2 3.65Å; H123-H129 AromaticContact NE2-CE1 3.78Å; H123-H129 AromaticContact NE2-NE2 3.53Å; H123-M176 WeakPolarHBondContact CE1-CE 3.42Å; H123-M176 VanDerWaalsContact ND1-CE 3.32Å; H123-M176 WeakPolarHBondContact ND1-CE 3.15Å
124A97Very high93.8Very high0 Ų09.5 Ų9.50%04%0.044CC..Hα-helixtrans-59.1-37.1178.800000113.1W38 L84 S94 D95 G97 L105 E120 L121 G126W38-A124 PolarHBondContact NE1-O 2.77Å; L84-A124 HydrophobicContact CD1-CB 3.71Å; L84-A124 HydrophobicContact CD2-CB 4.04Å; L84-A124 HydrophobicContact CG-CB 4.5Å; S94-A124 WeakPolarHBondContact OG-CB 3.03Å; S94-A124 PolarHBondContact OG-N 2.94Å; D95-A124 WeakPolarHBondContact O-CA 3.44Å; D95-A124 PolarHBondContact O-N 3.01Å; G97-A124 CarbonylContact C-O 3.47Å; G97-A124 VanDerWaalsContact CA-O 3.22Å; G97-A124 WeakPolarHBondContact CA-O 3.25Å; G97-A124 PolarHBondContact N-O 2.93Å; L105-A124 HydrophobicContact CD1-CB 4.15Å; E120-A124 PolarHBondContact O-N 3.14Å; L121-A124 WeakPolarHBondContact O-CB 3.4Å; L121-A124 PolarHBondContact O-N 3.18Å; A124-G126 PolarHBondContact O-N 2.96Å
125V96.8Very high93.3Very high0 Ų08 Ų80%04%0.039CC..Hα-helixtrans-61.2-34.1173.3165.50000110.9I43 Y66 V72 F74 L121 M122 H123 F127 I216 M219 Y220I43-V125 HydrophobicContact CD1-CG2 3.73Å; Y66-V125 HydrophobicContact CD1-CG2 4.29Å; Y66-V125 HydrophobicContact CE1-CG2 3.77Å; V72-V125 HydrophobicContact CG1-CG2 4.15Å; F74-V125 HydrophobicContact CZ-CG2 3.94Å; L121-V125 WeakPolarHBondContact O-CB 3.43Å; L121-V125 WeakPolarHBondContact O-CG2 3.31Å; L121-V125 PolarHBondContact O-N 3.2Å; M122-V125 WeakPolarHBondContact O-CB 3.15Å; M122-V125 PolarHBondContact O-N 3.48Å; H123-V125 VanDerWaalsContact C-N 3.26Å; H123-V125 PolarHBondContact O-N 2.88Å; V125-F127 HydrophobicContact CG1-CD2 4.1Å; V125-F127 HydrophobicContact CG1-CE2 3.99Å; V125-I216 HydrophobicContact CG1-CG1 4.33Å; V125-I216 HydrophobicContact CG1-CG2 4.19Å; V125-M219 HydrophobicContact CG1-CE 3.91Å; V125-M219 WeakPolarHBondContact O-CE 3.46Å; V125-Y220 HydrophobicContact CG1-CD2 4.44Å; V125-Y220 HydrophobicContact CG1-CE2 3.62Å; V125-Y220 PolarHBondContact O-OH 2.7Å
126G93.3Very high93.2Very high0 Ų07 Ų70%03%0.032CC..THydrogen-bonded Turntrans133.325.9169.500000115.2G30 V31 M122 H123 A124G30-G126 CarbonylContact C-O 3.45Å; G30-G126 VanDerWaalsContact CA-O 3.26Å; G30-G126 WeakPolarHBondContact CA-O 3.45Å; V31-G126 WeakPolarHBondContact CG1-O 3.22Å; V31-G126 PolarHBondContact N-O 3.1Å; M122-G126 PolarHBondContact O-N 2.71Å; H123-G126 VanDerWaalsContact O-CA 3.25Å; H123-G126 WeakPolarHBondContact O-CA 3.43Å; H123-G126 PolarHBondContact O-N 2.86Å; A124-G126 PolarHBondContact O-N 2.96Å
127F92.9Very high93.2Very high0 Ų09 Ų90%04%0.042CC..BIsolated β-bridgetrans-106.3139.5179.6-69.1-88.4000112.7N29 M122 H123 V125 Y166 K215 I216 M219N29-F127 CarbonylContact O-C 3.44Å; N29-F127 VanDerWaalsContact O-CA 3.27Å; N29-F127 WeakPolarHBondContact O-CA 3.35Å; N29-F127 VanDerWaalsContact O-CD1 3.27Å; N29-F127 WeakPolarHBondContact O-CD1 3.47Å; M122-F127 HydrophobicContact CE-CB 3.97Å; M122-F127 HydrophobicContact CE-CD1 4.03Å; M122-F127 HydrophobicContact CE-CD2 3.77Å; M122-F127 HydrophobicContact CE-CE2 4.33Å; M122-F127 HydrophobicContact CE-CG 3.61Å; M122-F127 HydrophobicContact CG-CB 4.02Å; M122-F127 HydrophobicContact CG-CD2 3.86Å; M122-F127 HydrophobicContact CG-CG 4.18Å; M122-F127 PolarHBondContact O-N 2.72Å; H123-F127 WeakPolarHBondContact CA-O 3.5Å; H123-F127 PolarHBondContact ND1-O 3.17Å; V125-F127 HydrophobicContact CG1-CD2 4.1Å; V125-F127 HydrophobicContact CG1-CE2 3.99Å; F127-Y166 HydrophobicContact CE1-CD2 4.41Å; F127-Y166 HydrophobicContact CE1-CE2 4.22Å; F127-Y166 HydrophobicContact CZ-CE2 4.36Å; F127-K215 HydrophobicContact CE1-CB 3.62Å; F127-K215 HydrophobicContact CE1-CD 4.33Å; F127-K215 HydrophobicContact CE1-CG 4.47Å; F127-K215 HydrophobicContact CZ-CB 3.83Å; F127-I216 HydrophobicContact CD2-CG1 4.15Å; F127-I216 HydrophobicContact CE2-CB 4.25Å; F127-I216 HydrophobicContact CE2-CG1 3.47Å; F127-I216 VanDerWaalsContact CE2-CG1 3.47Å; F127-I216 HydrophobicContact CZ-CG1 4.03Å; F127-M219 HydrophobicContact CD2-CE 4.02Å; F127-M219 HydrophobicContact CE2-CE 3.31Å; F127-M219 HydrophobicContact CE2-SD 4.01Å; F127-M219 HydrophobicContact CZ-CB 4.26Å; F127-M219 HydrophobicContact CZ-CE 3.77Å; F127-M219 HydrophobicContact CZ-SD 3.85Å
128W90.7Very high93Very high6 Ų614.8 Ų14.82%0.0237%0.069CC..  trans-87.7174.4164.5-61.199.2000109.1Y7 I11 A15 R19 N29 V96 A158Y7-W128 AromaticContact CD1-CZ3 3.87Å; Y7-W128 HydrophobicContact CD1-CZ3 3.87Å; Y7-W128 HydrophobicContact CE1-CE3 4.37Å; Y7-W128 AromaticContact CE1-CZ3 3.88Å; Y7-W128 HydrophobicContact CE1-CZ3 3.88Å; I11-W128 HydrophobicContact CD1-CE3 3.38Å; I11-W128 HydrophobicContact CD1-CZ3 3.61Å; I11-W128 HydrophobicContact CG2-CZ3 3.9Å; A15-W128 HydrophobicContact CB-CH2 4.33Å; A15-W128 HydrophobicContact CB-CZ2 4.39Å; R19-W128 HydrophobicContact CB-CH2 4.29Å; R19-W128 VanDerWaalsContact CD-CH2 3.49Å; R19-W128 VanDerWaalsContact NH1-CZ3 3.27Å; N29-W128 PolarHBondContact O-N 2.93Å; V96-W128 HydrophobicContact CB-CD2 4.16Å; V96-W128 HydrophobicContact CB-CE3 4.31Å; V96-W128 HydrophobicContact CB-CH2 4.04Å; V96-W128 HydrophobicContact CB-CZ2 3.86Å; V96-W128 HydrophobicContact CB-CZ3 4.27Å; V96-W128 HydrophobicContact CG1-CD2 3.99Å; V96-W128 HydrophobicContact CG1-CG 4.25Å; V96-W128 HydrophobicContact CG1-CZ2 4.09Å; V96-W128 HydrophobicContact CG2-CD2 3.78Å; V96-W128 HydrophobicContact CG2-CE3 3.58Å; V96-W128 HydrophobicContact CG2-CG 4.49Å; V96-W128 HydrophobicContact CG2-CH2 4Å; V96-W128 HydrophobicContact CG2-CZ2 4.17Å; V96-W128 HydrophobicContact CG2-CZ3 3.71Å; W128-A158 HydrophobicContact CG-CB 4.36Å
129H93.5Very high92.9Very high0 Ų017.7 Ų17.70%08%0.081CC..  trans-66.5152.2176.9-64.7111.8000113.2Q8 D10 H119 H123 H131 E132 M176 Y178Q8-H129 PolarHBondContact O-CE1 3.35Å; D10-H129 IonicContact OD1-CE1 2.88Å; D10-H129 PolarHBondContact OD1-CE1 3.19Å; D10-H129 IonicContact OD1-NE2 2.77Å; D10-H129 PolarHBondContact OD1-NE2 3.04Å; D10-H129 IonicContact OD2-CE1 3.26Å; D10-H129 IonicContact OD2-NE2 2.83Å; D10-H129 PolarHBondContact OD2-NE2 3.12Å; H119-H129 AromaticContact CE1-CD2 3.71Å; H119-H129 AromaticContact CE1-NE2 3.65Å; H119-H129 AromaticContact NE2-CD2 3.73Å; H119-H129 AromaticContact NE2-NE2 3.28Å; H119-H129 PolarHBondContact NE2-NE2 3.06Å; H123-H129 AromaticContact CE1-CD2 3.99Å; H123-H129 AromaticContact CE1-CE1 3.74Å; H123-H129 AromaticContact CE1-NE2 3.65Å; H123-H129 AromaticContact NE2-CE1 3.78Å; H123-H129 AromaticContact NE2-NE2 3.53Å; H129-H131 WeakPolarHBondContact CB-CE1 3.12Å; H129-H131 VanDerWaalsContact CB-ND1 3.3Å; H129-H131 WeakPolarHBondContact CB-ND1 3.16Å; H129-H131 AromaticContact CG-CE1 3.66Å; H129-H131 AromaticContact ND1-CE1 3.94Å; H129-E132 HydrophobicContact CB-CG 4.02Å; H129-E132 WeakPolarHBondContact O-CB 3.31Å; H129-E132 PolarHBondContact O-N 2.73Å; H129-E132 VanDerWaalsContact O-N 3.17Å; H129-M176 CarbonylContact C-O 3.51Å; H129-M176 WeakPolarHBondContact CA-O 3.47Å; H129-M176 WeakPolarHBondContact CB-O 3.39Å; H129-M176 PolarHBondContact CD2-O 3.24Å; H129-Y178 AromaticContact CD2-CD1 3.86Å; H129-Y178 AromaticContact CD2-CE1 3.56Å; H129-Y178 AromaticContact CE1-CE1 3.41Å; H129-Y178 VanDerWaalsContact CE1-CE1 3.41Å; H129-Y178 WeakPolarHBondContact CE1-CE1 3.26Å; H129-Y178 AromaticContact CE1-CZ 3.76Å; H129-Y178 AromaticContact CG-CE1 3.9Å; H129-Y178 AromaticContact ND1-CE1 3.81Å; H129-Y178 AromaticContact ND1-CZ 3.96Å; H129-Y178 AromaticContact NE2-CD1 3.94Å; H129-Y178 AromaticContact NE2-CE1 3.22Å; H129-Y178 WeakPolarHBondContact NE2-CE1 3.08Å
130E94.8Very high92.9Very high0 Ų016.5 Ų16.50%08%0.075CC..G310 helixtrans-69.9-33.6178.9-168.170.7178.600112.1N29 E132 R133 Y170 D171 M176 H177 K215N29-E130 PolarHBondContact ND2-OE2 2.81Å; E130-E132 PolarHBondContact O-N 3.48Å; E130-R133 WeakPolarHBondContact O-CB 3.31Å; E130-R133 WeakPolarHBondContact O-CG 3.41Å; E130-R133 PolarHBondContact O-N 2.92Å; E130-R133 WeakPolarHBondContact OE1-CD 3.47Å; E130-R133 IonicContact OE1-CZ 3.38Å; E130-R133 IonicContact OE1-NE 3.92Å; E130-R133 IonicContact OE1-NH1 2.71Å; E130-R133 PolarHBondContact OE1-NH1 2.71Å; E130-Y170 HydrophobicContact CG-CE1 4.23Å; E130-Y170 HydrophobicContact CG-CE2 4.15Å; E130-Y170 VanDerWaalsContact O-CE2 3.3Å; E130-Y170 WeakPolarHBondContact O-CE2 3.13Å; E130-D171 PolarHBondContact OE1-N 3.06Å; E130-M176 PolarHBondContact N-O 2.98Å; E130-H177 HydrophobicContact CB-CB 4.01Å; E130-K215 IonicContact OE1-NZ 3.65Å; E130-K215 PolarHBondContact OE1-NZ 2.62Å; E130-K215 IonicContact OE2-NZ 2.61Å; E130-K215 PolarHBondContact OE2-NZ 2.52Å
131H93.3Very high92.9Very high0 Ų020.1 Ų20.10%010%0.095CC..G310 helixtrans-73.6-4.417476.2-74.1000112.6H129 R133 R136 I140 Q154 Y170 Y178 I191H129-H131 WeakPolarHBondContact CB-CE1 3.12Å; H129-H131 VanDerWaalsContact CB-ND1 3.3Å; H129-H131 WeakPolarHBondContact CB-ND1 3.16Å; H129-H131 AromaticContact CG-CE1 3.66Å; H129-H131 AromaticContact ND1-CE1 3.94Å; H131-R133 VanDerWaalsContact C-N 3.33Å; H131-R136 WeakPolarHBondContact O-CD 3.39Å; H131-R136 PolarHBondContact O-NH1 2.8Å; H131-I140 HydrophobicContact CB-CD1 3.75Å; H131-Q154 PolarHBondContact NE2-O 2.96Å; H131-Y170 WeakPolarHBondContact CA-OH 3.26Å; H131-Y178 AromaticContact CD2-CD2 3.99Å; H131-Y178 AromaticContact CE1-CD1 3.76Å; H131-Y178 AromaticContact CE1-CD2 3.09Å; H131-Y178 WeakPolarHBondContact CE1-CD2 3.47Å; H131-Y178 AromaticContact CE1-CE1 3.86Å; H131-Y178 AromaticContact CE1-CE2 3.15Å; H131-Y178 WeakPolarHBondContact CE1-CE2 2.91Å; H131-Y178 AromaticContact CE1-CG 3.4Å; H131-Y178 AromaticContact CE1-CZ 3.56Å; H131-Y178 AromaticContact ND1-CD2 3.63Å; H131-Y178 AromaticContact ND1-CG 3.57Å; H131-Y178 AromaticContact NE2-CD2 3.34Å; H131-Y178 VanDerWaalsContact NE2-CD2 3.34Å; H131-Y178 WeakPolarHBondContact NE2-CD2 3.32Å; H131-Y178 AromaticContact NE2-CE2 3.31Å; H131-Y178 VanDerWaalsContact NE2-CE2 3.31Å; H131-Y178 WeakPolarHBondContact NE2-CE2 3.28Å; H131-I191 HydrophobicContact CB-CD1 4.2Å
132E89.3Confident92.7Very high0 Ų021 Ų210%010%0.099CC..G310 helixtrans-89.9-3174-67.5-167.9110.100112.6Y7 Q8 R19 A27 H129 E130 G156 K157 A158Y7-E132 PolarHBondContact OH-OE1 3.25Å; Q8-E132 WeakPolarHBondContact CG-OE1 3.35Å; Q8-E132 PolarHBondContact NE2-OE1 3.08Å; Q8-E132 PolarHBondContact OE1-OE1 3.16Å; R19-E132 IonicContact CZ-OE1 3.16Å; R19-E132 IonicContact CZ-OE2 2.67Å; R19-E132 VanDerWaalsContact NH1-CD 3.34Å; R19-E132 IonicContact NH1-OE1 3.75Å; R19-E132 PolarHBondContact NH1-OE1 3.37Å; R19-E132 IonicContact NH1-OE2 4Å; R19-E132 PolarHBondContact NH1-OE2 2.76Å; R19-E132 IonicContact NH2-OE1 3.6Å; R19-E132 PolarHBondContact NH2-OE1 3.12Å; R19-E132 IonicContact NH2-OE2 2.64Å; A27-E132 WeakPolarHBondContact CB-O 3.26Å; H129-E132 HydrophobicContact CB-CG 4.02Å; H129-E132 WeakPolarHBondContact O-CB 3.31Å; H129-E132 PolarHBondContact O-N 2.73Å; H129-E132 VanDerWaalsContact O-N 3.17Å; E130-E132 PolarHBondContact O-N 3.48Å; E132-G156 VanDerWaalsContact CG-O 3.31Å; E132-G156 WeakPolarHBondContact CG-O 3.37Å; E132-K157 CarbonylContact O-C 3.49Å; E132-K157 VanDerWaalsContact O-CA 3.29Å; E132-K157 WeakPolarHBondContact O-CA 2.97Å; E132-A158 HydrophobicContact CB-CB 4.32Å; E132-A158 PolarHBondContact O-N 3.21Å
133R87.7Confident92.5Very high2 Ų222.3 Ų22.31%0.00811%0.106CC..  trans-56.6154.4175.5-66.6-176.856.1128.4-0.4112.1A27 N29 E130 H131 D135 R136 F165 E168 R169 Y170A27-R133 CarbonylContact O-C 3.59Å; N29-R133 HydrophobicContact CB-CG 3.9Å; E130-R133 WeakPolarHBondContact O-CB 3.31Å; E130-R133 WeakPolarHBondContact O-CG 3.41Å; E130-R133 PolarHBondContact O-N 2.92Å; E130-R133 WeakPolarHBondContact OE1-CD 3.47Å; E130-R133 IonicContact OE1-CZ 3.38Å; E130-R133 IonicContact OE1-NE 3.92Å; E130-R133 IonicContact OE1-NH1 2.71Å; E130-R133 PolarHBondContact OE1-NH1 2.71Å; H131-R133 VanDerWaalsContact C-N 3.33Å; R133-D135 VanDerWaalsContact CB-OD1 3.26Å; R133-D135 WeakPolarHBondContact CB-OD1 3.42Å; R133-D135 IonicContact CZ-OD1 3.29Å; R133-D135 IonicContact CZ-OD2 3.4Å; R133-D135 IonicContact NE-OD1 3.82Å; R133-D135 PolarHBondContact NE-OD1 2.69Å; R133-D135 IonicContact NE-OD2 3.41Å; R133-D135 IonicContact NH2-OD1 3.34Å; R133-D135 IonicContact NH2-OD2 2.77Å; R133-D135 PolarHBondContact NH2-OD2 3.4Å; R133-R136 HydrophobicContact CB-CB 4.3Å; R133-R136 VanDerWaalsContact O-CB 3.25Å; R133-R136 WeakPolarHBondContact O-CB 3.45Å; R133-R136 WeakPolarHBondContact O-CD 3.36Å; R133-R136 VanDerWaalsContact O-CG 3.3Å; R133-R136 WeakPolarHBondContact O-CG 3.33Å; R133-R136 PolarHBondContact O-N 2.94Å; R133-F165 HydrophobicContact CB-CE1 3.58Å; R133-F165 HydrophobicContact CB-CZ 3.74Å; R133-F165 HydrophobicContact CG-CD1 4.1Å; R133-F165 HydrophobicContact CG-CE1 3.36Å; R133-F165 HydrophobicContact CG-CZ 4Å; R133-F165 VanDerWaalsContact CZ-CE1 3.49Å; R133-F165 VanDerWaalsContact CZ-CG 3.49Å; R133-F165 VanDerWaalsContact NH2-CE2 3.27Å; R133-F165 VanDerWaalsContact NH2-CG 3.33Å; R133-E168 PolarHBondContact NH1-O 3.19Å; R133-E168 PolarHBondContact NH2-O 3.03Å; R133-E168 VanDerWaalsContact NH2-O 3.14Å; R133-R169 PolarHBondContact NH1-O 2.76Å; R133-Y170 HydrophobicContact CB-CD2 4.38Å; R133-Y170 HydrophobicContact CB-CE2 4.26Å; R133-Y170 HydrophobicContact CG-CD2 4.45Å; R133-Y170 HydrophobicContact CG-CE2 4.42Å
134W80.4Confident92.3Very high50 Ų5027.4 Ų27.419%0.18913%0.125CC..G310 helixtrans-77.5-38.2-175.171.7-98.8000113.7V26 A27 R136 K157 F165 Y304V26-W134 HydrophobicContact CB-CB 4.25Å; V26-W134 HydrophobicContact CG1-CB 3.29Å; V26-W134 HydrophobicContact CG1-CD2 3.48Å; V26-W134 VanDerWaalsContact CG1-CD2 3.48Å; V26-W134 HydrophobicContact CG1-CE3 3.83Å; V26-W134 HydrophobicContact CG1-CG 3.23Å; A27-W134 HydrophobicContact CB-CB 3.78Å; A27-W134 WeakPolarHBondContact O-CA 3.35Å; A27-W134 WeakPolarHBondContact O-CB 2.98Å; A27-W134 PolarHBondContact O-N 3.06Å; W134-R136 PolarHBondContact O-N 2.86Å; W134-K157 PolarHBondContact O-NZ 3.46Å; W134-F165 AromaticContact CD1-CE2 3.21Å; W134-F165 AromaticContact CD1-CZ 3.1Å; W134-F165 AromaticContact CE2-CE2 3.9Å; W134-F165 HydrophobicContact CG-CE2 4.17Å; W134-F165 AromaticContact CG-CZ 3.91Å; W134-F165 HydrophobicContact CG-CZ 3.91Å; W134-F165 AromaticContact NE1-CD2 3.92Å; W134-F165 AromaticContact NE1-CE2 2.98Å; W134-F165 AromaticContact NE1-CZ 3.46Å; W134-Y304 HydrophobicContact CH2-CE1 4.02Å; W134-Y304 WeakPolarHBondContact CH2-OH 3.3Å; W134-Y304 HydrophobicContact CZ3-CE1 4.26Å
135D85.1Confident92.1Very high15 Ų1532.5 Ų32.58%0.0815%0.149CC..G310 helixtrans-79.4-1.1176.359.5-10.7000111.1R133 D137 E138 Y139 F165R133-D135 VanDerWaalsContact CB-OD1 3.26Å; R133-D135 WeakPolarHBondContact CB-OD1 3.42Å; R133-D135 IonicContact CZ-OD1 3.29Å; R133-D135 IonicContact CZ-OD2 3.4Å; R133-D135 IonicContact NE-OD1 3.82Å; R133-D135 PolarHBondContact NE-OD1 2.69Å; R133-D135 IonicContact NE-OD2 3.41Å; R133-D135 IonicContact NH2-OD1 3.34Å; R133-D135 IonicContact NH2-OD2 2.77Å; R133-D135 PolarHBondContact NH2-OD2 3.4Å; D135-D137 PolarHBondContact O-N 2.77Å; D135-E138 VanDerWaalsContact O-CB 3.32Å; D135-E138 WeakPolarHBondContact O-CB 3.32Å; D135-E138 PolarHBondContact O-N 3.04Å; D135-Y139 HydrophobicContact CB-CE2 4.21Å; D135-Y139 WeakPolarHBondContact O-CD2 3.42Å; D135-F165 HydrophobicContact CB-CE2 4.47Å; D135-F165 WeakPolarHBondContact OD1-CE2 3.48Å; D135-F165 WeakPolarHBondContact OD1-CZ 3.32Å; D135-F165 VanDerWaalsContact OD2-CE2 3.31Å; D135-F165 WeakPolarHBondContact OD2-CE2 3.31Å
136R90.7Very high92.1Very high10 Ų1033.2 Ų33.24%0.03815%0.153CC..G310 helixtrans-51.8-33.8-177.181-175.1-179.5-1583.3113.2H131 R133 W134 E138 Y139 I140 F155 K157 Y170H131-R136 WeakPolarHBondContact O-CD 3.39Å; H131-R136 PolarHBondContact O-NH1 2.8Å; R133-R136 HydrophobicContact CB-CB 4.3Å; R133-R136 VanDerWaalsContact O-CB 3.25Å; R133-R136 WeakPolarHBondContact O-CB 3.45Å; R133-R136 WeakPolarHBondContact O-CD 3.36Å; R133-R136 VanDerWaalsContact O-CG 3.3Å; R133-R136 WeakPolarHBondContact O-CG 3.33Å; R133-R136 PolarHBondContact O-N 2.94Å; W134-R136 PolarHBondContact O-N 2.86Å; R136-E138 PolarHBondContact O-N 3.47Å; R136-E138 VanDerWaalsContact O-N 3.14Å; R136-Y139 CarbonylContact O-C 3.11Å; R136-Y139 WeakPolarHBondContact O-CA 3.36Å; R136-Y139 PolarHBondContact O-N 2.9Å; R136-I140 HydrophobicContact CB-CD1 4.12Å; R136-I140 HydrophobicContact CB-CG1 3.92Å; R136-I140 HydrophobicContact CG-CD1 4.27Å; R136-I140 HydrophobicContact CG-CG1 4.1Å; R136-I140 VanDerWaalsContact O-CG1 3.26Å; R136-I140 WeakPolarHBondContact O-CG1 3.22Å; R136-I140 PolarHBondContact O-N 2.77Å; R136-F155 PolarHBondContact NH1-O 3.44Å; R136-F155 PolarHBondContact NH2-O 2.98Å; R136-K157 VanDerWaalsContact NE-CE 3.32Å; R136-Y170 HydrophobicContact CB-CD2 4.5Å; R136-Y170 HydrophobicContact CB-CE2 3.74Å
137D90.9Very high91.7Very high76 Ų7633.2 Ų33.241%0.40615%0.153SC..G310 helixtrans-72.4-7.8-174-60.2-11.6000111.1D135 Y139 I140 K157D135-D137 PolarHBondContact O-N 2.77Å; D137-Y139 VanDerWaalsContact C-N 3.34Å; D137-I140 WeakPolarHBondContact CA-O 3.42Å; D137-K157 WeakPolarHBondContact OD1-CE 3.17Å; D137-K157 IonicContact OD1-NZ 3.32Å; D137-K157 WeakPolarHBondContact OD2-CE 3.33Å; D137-K157 IonicContact OD2-NZ 2.77Å; D137-K157 PolarHBondContact OD2-NZ 2.67Å
138E93Very high91.3Very high122 Ų12234.3 Ų34.357%0.5716%0.162SC*.G310 helixtrans-81.1-14.7166.7-57.8179.1-156.400112.5D135 R136D135-E138 VanDerWaalsContact O-CB 3.32Å; D135-E138 WeakPolarHBondContact O-CB 3.32Å; D135-E138 PolarHBondContact O-N 3.04Å; R136-E138 PolarHBondContact O-N 3.47Å; R136-E138 VanDerWaalsContact O-N 3.14Å
139Y95.9Very high90.9Very high62 Ų6242 Ų4224%0.24320%0.195CC..THydrogen-bonded Turntrans-122.2-29.3-171.1-59.4-79.1000113.2D135 R136 D137 Y170 Y172 V194D135-Y139 HydrophobicContact CB-CE2 4.21Å; D135-Y139 WeakPolarHBondContact O-CD2 3.42Å; R136-Y139 CarbonylContact O-C 3.11Å; R136-Y139 WeakPolarHBondContact O-CA 3.36Å; R136-Y139 PolarHBondContact O-N 2.9Å; D137-Y139 VanDerWaalsContact C-N 3.34Å; Y139-Y170 HydrophobicContact CD1-CD1 4.33Å; Y139-Y170 HydrophobicContact CD1-CG 4.04Å; Y139-Y170 VanDerWaalsContact CD2-CB 3.41Å; Y139-Y170 HydrophobicContact CD2-CD1 4.41Å; Y139-Y170 AromaticContact CD2-CD2 3.58Å; Y139-Y170 HydrophobicContact CD2-CD2 3.58Å; Y139-Y170 HydrophobicContact CD2-CE2 4.48Å; Y139-Y170 AromaticContact CD2-CG 3.55Å; Y139-Y170 HydrophobicContact CD2-CG 3.55Å; Y139-Y170 HydrophobicContact CE2-CD2 4.28Å; Y139-Y170 HydrophobicContact CE2-CG 4.16Å; Y139-Y170 VanDerWaalsContact CG-CB 3.45Å; Y139-Y170 AromaticContact CG-CD1 3.9Å; Y139-Y170 HydrophobicContact CG-CD1 3.9Å; Y139-Y170 AromaticContact CG-CD2 3.91Å; Y139-Y170 HydrophobicContact CG-CD2 3.91Å; Y139-Y170 AromaticContact CG-CG 3.47Å; Y139-Y170 HydrophobicContact CG-CG 3.47Å; Y139-Y170 VanDerWaalsContact CG-CG 3.47Å; Y139-Y172 WeakPolarHBondContact CA-OH 2.96Å; Y139-Y172 WeakPolarHBondContact CB-OH 3.25Å; Y139-Y172 WeakPolarHBondContact O-CE1 3.45Å; Y139-Y172 PolarHBondContact O-OH 3Å; Y139-V194 WeakPolarHBondContact O-CB 3.33Å; Y139-V194 WeakPolarHBondContact O-CG2 3.43Å; Y139-V194 PolarHBondContact O-N 2.85Å
140I96.7Very high90.3Very high0 Ų048.7 Ų48.70%023%0.231CC..EExtended strand (participates in β ladder)trans-138.1147.8-178.560.6166.1000111.3H131 R136 D137 I142 Y170 Y172 I191 E192H131-I140 HydrophobicContact CB-CD1 3.75Å; R136-I140 HydrophobicContact CB-CD1 4.12Å; R136-I140 HydrophobicContact CB-CG1 3.92Å; R136-I140 HydrophobicContact CG-CD1 4.27Å; R136-I140 HydrophobicContact CG-CG1 4.1Å; R136-I140 VanDerWaalsContact O-CG1 3.26Å; R136-I140 WeakPolarHBondContact O-CG1 3.22Å; R136-I140 PolarHBondContact O-N 2.77Å; D137-I140 WeakPolarHBondContact CA-O 3.42Å; I140-I142 HydrophobicContact CD1-CD1 3.72Å; I140-I142 HydrophobicContact CG1-CD1 4.41Å; I140-Y170 WeakPolarHBondContact CD1-OH 3.42Å; I140-Y170 HydrophobicContact CG2-CE1 4.23Å; I140-Y172 HydrophobicContact CG2-CE1 3.95Å; I140-I191 HydrophobicContact CB-CG2 3.82Å; I140-I191 HydrophobicContact CD1-CG2 3.81Å; I140-I191 HydrophobicContact CG1-CG2 4.39Å; I140-I191 HydrophobicContact CG2-CG2 3.94Å; I140-E192 CarbonylContact C-O 3.2Å; I140-E192 VanDerWaalsContact CA-O 3.22Å; I140-E192 WeakPolarHBondContact CA-O 3.31Å
141N96.5Very high89.6Confident79 Ų7949 Ų4942%0.42223%0.234SC..EExtended strand (participates in β ladder)trans-101.2127.8167.8-62.8-54.8000109I191 E192N141-I191 WeakPolarHBondContact O-CA 3.31Å; N141-E192 HydrophobicContact CB-CB 4.48Å; N141-E192 PolarHBondContact N-O 2.91Å; N141-E192 PolarHBondContact O-N 2.81Å
142I94.2Very high88.9Confident18 Ų1853.4 Ų53.49%0.09225%0.251CS..EExtended strand (participates in β ladder)trans-89.7115.5170.6-56.1-53.1000108.4I140 W144 I147 F155 I191I140-I142 HydrophobicContact CD1-CD1 3.72Å; I140-I142 HydrophobicContact CG1-CD1 4.41Å; I142-W144 HydrophobicContact CB-CZ2 4.27Å; I142-W144 HydrophobicContact CG2-CD2 3.8Å; I142-W144 HydrophobicContact CG2-CE3 4.24Å; I142-W144 HydrophobicContact CG2-CG 4.21Å; I142-W144 HydrophobicContact CG2-CH2 4.28Å; I142-W144 HydrophobicContact CG2-CZ2 3.85Å; I142-W144 HydrophobicContact CG2-CZ3 4.46Å; I142-W144 PolarHBondContact O-N 2.8Å; I142-W144 VanDerWaalsContact O-N 3.16Å; I142-I147 HydrophobicContact CG2-CD1 3.45Å; I142-I147 VanDerWaalsContact CG2-CD1 3.45Å; I142-F155 HydrophobicContact CD1-CD1 3.92Å; I142-F155 HydrophobicContact CG2-CB 4.29Å; I142-F155 HydrophobicContact CG2-CD1 4Å; I142-F155 HydrophobicContact CG2-CG 4.25Å; I142-I191 HydrophobicContact CD1-CG1 4.01Å; I142-I191 HydrophobicContact CD1-CG2 4.45Å
143L95Very high88.1Confident29 Ų2956.7 Ų56.715%0.15227%0.269CS..  trans-87.475.3179.7-57.7-177.1000110.2E145 N146 R189 T190 E192L143-E145 PolarHBondContact O-N 3.39Å; L143-E145 VanDerWaalsContact O-N 3.08Å; L143-N146 HydrophobicContact CB-CB 4.46Å; L143-N146 PolarHBondContact O-N 2.86Å; L143-R189 HydrophobicContact CD1-CB 4.35Å; L143-R189 WeakPolarHBondContact CD1-O 3.45Å; L143-T190 PolarHBondContact N-O 2.83Å; L143-E192 HydrophobicContact CD1-CG 3.73Å; L143-E192 HydrophobicContact CG-CG 4.31Å
144W91.6Very high87.8Confident107 Ų10757.3 Ų57.341%0.40527%0.272SS..G310 helixtrans-53.1-30.4-174-6497.7000114.5I142 N146 I147 Y152 F155I142-W144 HydrophobicContact CB-CZ2 4.27Å; I142-W144 HydrophobicContact CG2-CD2 3.8Å; I142-W144 HydrophobicContact CG2-CE3 4.24Å; I142-W144 HydrophobicContact CG2-CG 4.21Å; I142-W144 HydrophobicContact CG2-CH2 4.28Å; I142-W144 HydrophobicContact CG2-CZ2 3.85Å; I142-W144 HydrophobicContact CG2-CZ3 4.46Å; I142-W144 PolarHBondContact O-N 2.8Å; I142-W144 VanDerWaalsContact O-N 3.16Å; W144-N146 PolarHBondContact O-N 3.39Å; W144-I147 HydrophobicContact CD2-CD1 4.42Å; W144-I147 HydrophobicContact CE3-CD1 4.03Å; W144-I147 PolarHBondContact O-N 3.46Å; W144-Y152 HydrophobicContact CE3-CD1 4.22Å; W144-Y152 HydrophobicContact CE3-CE1 4.44Å; W144-Y152 HydrophobicContact CE3-CG 4.28Å; W144-Y152 HydrophobicContact CZ3-CG 4.32Å; W144-Y152 PolarHBondContact O-OH 2.91Å; W144-F155 HydrophobicContact CH2-CB 3.93Å; W144-F155 HydrophobicContact CZ3-CB 4.11Å
145E92.8Very high88Confident107 Ų10754.9 Ų54.950%0.526%0.263SS..G310 helixtrans-68-20.217768.9-84.6-16100113.7L143 R185L143-E145 PolarHBondContact O-N 3.39Å; L143-E145 VanDerWaalsContact O-N 3.08Å; E145-R185 PolarHBondContact O-NE 3.07Å; E145-R185 PolarHBondContact O-NH2 2.81Å
146N95.5Very high87.6Confident15 Ų1555.3 Ų55.38%0.0827%0.27CS..G310 helixtrans-97.6-9.1178.3-64.7-32.4000112.8L143 W144 T184 R185 N186 R189 T190L143-N146 HydrophobicContact CB-CB 4.46Å; L143-N146 PolarHBondContact O-N 2.86Å; W144-N146 PolarHBondContact O-N 3.39Å; N146-T184 CarbonylContact O-C 3.58Å; N146-T184 WeakPolarHBondContact O-CA 3.15Å; N146-R185 WeakPolarHBondContact O-CG 3.32Å; N146-R185 PolarHBondContact O-N 2.95Å; N146-N186 PolarHBondContact OD1-ND2 2.95Å; N146-R189 VanDerWaalsContact CB-O 3.25Å; N146-R189 WeakPolarHBondContact CB-O 3.48Å; N146-R189 PolarHBondContact ND2-O 3.14Å; N146-T190 HydrophobicContact CB-CG2 4.17Å
147I85.7Confident87.1Confident0 Ų058 Ų580%028%0.282CS..BIsolated β-bridgetrans-86.6140.7-177.8-56.5166.5000110.2I142 W144 A151 Y152 F155 F183 T190I142-I147 HydrophobicContact CG2-CD1 3.45Å; I142-I147 VanDerWaalsContact CG2-CD1 3.45Å; W144-I147 HydrophobicContact CD2-CD1 4.42Å; W144-I147 HydrophobicContact CE3-CD1 4.03Å; W144-I147 PolarHBondContact O-N 3.46Å; I147-A151 HydrophobicContact CG2-CB 4.15Å; I147-Y152 HydrophobicContact CB-CD1 4.1Å; I147-Y152 HydrophobicContact CB-CE1 3.89Å; I147-Y152 HydrophobicContact CG2-CD1 3.79Å; I147-Y152 HydrophobicContact CG2-CE1 4.08Å; I147-F155 HydrophobicContact CB-CE2 4.42Å; I147-F155 HydrophobicContact CD1-CD1 4.14Å; I147-F155 HydrophobicContact CD1-CD2 3.71Å; I147-F155 HydrophobicContact CD1-CE1 4.17Å; I147-F155 HydrophobicContact CD1-CE2 3.78Å; I147-F155 HydrophobicContact CD1-CG 3.91Å; I147-F155 HydrophobicContact CD1-CZ 4Å; I147-F155 HydrophobicContact CG1-CD2 4.37Å; I147-F155 HydrophobicContact CG1-CE2 3.97Å; I147-F155 HydrophobicContact CG1-CZ 4.13Å; I147-F155 HydrophobicContact CG2-CD2 3.87Å; I147-F155 HydrophobicContact CG2-CE2 3.51Å; I147-F155 HydrophobicContact CG2-CZ 4.39Å; I147-F183 HydrophobicContact CG2-CB 4.42Å; I147-T190 HydrophobicContact CB-CG2 4.4Å; I147-T190 HydrophobicContact CG1-CG2 3.57Å
148A84Confident86Confident23 Ų2354.4 Ų54.419%0.1926%0.263CS..  trans-60.7135.917100000110.5D150 A151 Y152 F183 R185A148-D150 VanDerWaalsContact C-N 3.26Å; A148-D150 VanDerWaalsContact CB-OD1 3.27Å; A148-D150 WeakPolarHBondContact CB-OD1 3.35Å; A148-D150 PolarHBondContact O-N 3.38Å; A148-A151 HydrophobicContact CB-CB 4.17Å; A148-A151 WeakPolarHBondContact O-CA 3.05Å; A148-A151 WeakPolarHBondContact O-CB 3.11Å; A148-A151 PolarHBondContact O-N 2.69Å; A148-Y152 WeakPolarHBondContact O-CD1 3.36Å; A148-F183 PolarHBondContact N-O 2.69Å; A148-R185 HydrophobicContact CB-CB 4.25Å
149K81.6Confident84.5Confident166 Ų16649.1 Ų49.172%0.72224%0.239SC*.G310 helixtrans-62.6-34.4-169.8-73.3-174.2176.1-177.50113.3A151K149-A151 PolarHBondContact O-N 3.17Å
150D80.7Confident82.6Confident142 Ų14246.8 Ų46.876%0.75923%0.23SC*.G310 helixtrans-72.1-11174.456.5-31.6000113.3A148A148-D150 VanDerWaalsContact C-N 3.26Å; A148-D150 VanDerWaalsContact CB-OD1 3.27Å; A148-D150 WeakPolarHBondContact CB-OD1 3.35Å; A148-D150 PolarHBondContact O-N 3.38Å
151A80.2Confident80.6Confident7 Ų750.9 Ų50.96%0.05825%0.252CS..G310 helixtrans-105.610.3179.300000113.9I147 A148 K149 D153 Q154 F155 F183I147-A151 HydrophobicContact CG2-CB 4.15Å; A148-A151 HydrophobicContact CB-CB 4.17Å; A148-A151 WeakPolarHBondContact O-CA 3.05Å; A148-A151 WeakPolarHBondContact O-CB 3.11Å; A148-A151 PolarHBondContact O-N 2.69Å; K149-A151 PolarHBondContact O-N 3.17Å; A151-D153 VanDerWaalsContact C-N 3.26Å; A151-D153 PolarHBondContact O-N 2.83Å; A151-Q154 HydrophobicContact CB-CB 4.49Å; A151-Q154 HydrophobicContact CB-CG 3.85Å; A151-Q154 WeakPolarHBondContact O-CB 3.24Å; A151-Q154 VanDerWaalsContact O-CG 3.25Å; A151-Q154 WeakPolarHBondContact O-CG 3.17Å; A151-Q154 PolarHBondContact O-N 2.87Å; A151-F155 WeakPolarHBondContact O-CD2 3.48Å; A151-F183 HydrophobicContact CB-CB 3.71Å; A151-F183 HydrophobicContact CB-CD1 3.72Å; A151-F183 HydrophobicContact CB-CG 3.91Å
152Y79.4Confident78.6Confident92 Ų9247.9 Ų47.936%0.36124%0.235SC..G310 helixtrans-63.8-32.4-179.1-79.16.3000113.2W144 I147 A148 Q154 F155W144-Y152 HydrophobicContact CE3-CD1 4.22Å; W144-Y152 HydrophobicContact CE3-CE1 4.44Å; W144-Y152 HydrophobicContact CE3-CG 4.28Å; W144-Y152 HydrophobicContact CZ3-CG 4.32Å; W144-Y152 PolarHBondContact O-OH 2.91Å; I147-Y152 HydrophobicContact CB-CD1 4.1Å; I147-Y152 HydrophobicContact CB-CE1 3.89Å; I147-Y152 HydrophobicContact CG2-CD1 3.79Å; I147-Y152 HydrophobicContact CG2-CE1 4.08Å; A148-Y152 WeakPolarHBondContact O-CD1 3.36Å; Y152-Q154 PolarHBondContact O-N 3.01Å; Y152-F155 PolarHBondContact O-N 3.17Å
153D73.4Confident76.9Confident69 Ų6947 Ų4737%0.36923%0.231SC..G310 helixtrans-65.6-26.4175.870.7-36.1000111.7Q8 A151 F155 G156Q8-D153 PolarHBondContact NE2-O 2.77Å; A151-D153 VanDerWaalsContact C-N 3.26Å; A151-D153 PolarHBondContact O-N 2.83Å; D153-F155 PolarHBondContact O-N 3.03Å; D153-F155 VanDerWaalsContact O-N 3.11Å; D153-G156 PolarHBondContact O-N 3.34Å
154Q79.9Confident75.6Confident14 Ų1447.8 Ų47.87%0.06524%0.235CC..G310 helixtrans-68-0.3175.6-40.5-65.6-66.300114.5Q8 H131 A151 Y152 F183Q8-Q154 VanDerWaalsContact CD-CA 3.49Å; Q8-Q154 VanDerWaalsContact NE2-CA 3.34Å; Q8-Q154 VanDerWaalsContact OE1-CA 3.24Å; Q8-Q154 PolarHBondContact OE1-O 3.4Å; H131-Q154 PolarHBondContact NE2-O 2.96Å; A151-Q154 HydrophobicContact CB-CB 4.49Å; A151-Q154 HydrophobicContact CB-CG 3.85Å; A151-Q154 WeakPolarHBondContact O-CB 3.24Å; A151-Q154 VanDerWaalsContact O-CG 3.25Å; A151-Q154 WeakPolarHBondContact O-CG 3.17Å; A151-Q154 PolarHBondContact O-N 2.87Å; Y152-Q154 PolarHBondContact O-N 3.01Å; Q154-F183 HydrophobicContact CB-CD2 4.04Å; Q154-F183 HydrophobicContact CB-CE1 4.36Å; Q154-F183 HydrophobicContact CB-CE2 3.89Å; Q154-F183 HydrophobicContact CB-CG 4.37Å; Q154-F183 HydrophobicContact CB-CZ 4.04Å; Q154-F183 HydrophobicContact CG-CD1 4.18Å; Q154-F183 HydrophobicContact CG-CE1 3.92Å; Q154-F183 HydrophobicContact CG-CE2 4.35Å; Q154-F183 HydrophobicContact CG-CG 4.49Å; Q154-F183 HydrophobicContact CG-CZ 4.02Å
155F84.2Confident74.7Confident0 Ų043.5 Ų43.50%022%0.219CC..G310 helixtrans-122.817.1171.9-64.5-96.2000111R136 I142 W144 I147 A151 Y152 D153 A182 F183 I191R136-F155 PolarHBondContact NH1-O 3.44Å; R136-F155 PolarHBondContact NH2-O 2.98Å; I142-F155 HydrophobicContact CD1-CD1 3.92Å; I142-F155 HydrophobicContact CG2-CB 4.29Å; I142-F155 HydrophobicContact CG2-CD1 4Å; I142-F155 HydrophobicContact CG2-CG 4.25Å; W144-F155 HydrophobicContact CH2-CB 3.93Å; W144-F155 HydrophobicContact CZ3-CB 4.11Å; I147-F155 HydrophobicContact CB-CE2 4.42Å; I147-F155 HydrophobicContact CD1-CD1 4.14Å; I147-F155 HydrophobicContact CD1-CD2 3.71Å; I147-F155 HydrophobicContact CD1-CE1 4.17Å; I147-F155 HydrophobicContact CD1-CE2 3.78Å; I147-F155 HydrophobicContact CD1-CG 3.91Å; I147-F155 HydrophobicContact CD1-CZ 4Å; I147-F155 HydrophobicContact CG1-CD2 4.37Å; I147-F155 HydrophobicContact CG1-CE2 3.97Å; I147-F155 HydrophobicContact CG1-CZ 4.13Å; I147-F155 HydrophobicContact CG2-CD2 3.87Å; I147-F155 HydrophobicContact CG2-CE2 3.51Å; I147-F155 HydrophobicContact CG2-CZ 4.39Å; A151-F155 WeakPolarHBondContact O-CD2 3.48Å; Y152-F155 PolarHBondContact O-N 3.17Å; D153-F155 PolarHBondContact O-N 3.03Å; D153-F155 VanDerWaalsContact O-N 3.11Å; F155-A182 HydrophobicContact CZ-CB 4.5Å; F155-A182 WeakPolarHBondContact CZ-O 3.34Å; F155-F183 HydrophobicContact CE2-CB 3.92Å; F155-F183 AromaticContact CE2-CD2 3.92Å; F155-F183 HydrophobicContact CE2-CD2 3.92Å; F155-F183 HydrophobicContact CE2-CG 4.25Å; F155-F183 HydrophobicContact CZ-CB 4.3Å; F155-F183 HydrophobicContact CZ-CD2 4.1Å; F155-I191 HydrophobicContact CD1-CG1 4.46Å; F155-I191 HydrophobicContact CE1-CD1 3.93Å; F155-I191 HydrophobicContact CE1-CG1 3.77Å
156G78.4Confident73.8Confident23 Ų2340 Ų4024%0.23720%0.202CC..  trans-64.1140.6174.800000111.8R19 E132 D153R19-G156 PolarHBondContact NH2-O 2.9Å; E132-G156 VanDerWaalsContact CG-O 3.31Å; E132-G156 WeakPolarHBondContact CG-O 3.37Å; D153-G156 PolarHBondContact O-N 3.34Å
157K80.5Confident73.1Confident67 Ų6742.8 Ų42.829%0.29123%0.234SC..  trans-72.9143.8171.6-66.4-178.9172.1-170.10109.4R19 A27 E132 W134 R136 D137R19-K157 PolarHBondContact NH2-O 2.67Å; A27-K157 HydrophobicContact CB-CB 3.63Å; E132-K157 CarbonylContact O-C 3.49Å; E132-K157 VanDerWaalsContact O-CA 3.29Å; E132-K157 WeakPolarHBondContact O-CA 2.97Å; W134-K157 PolarHBondContact O-NZ 3.46Å; R136-K157 VanDerWaalsContact NE-CE 3.32Å; D137-K157 WeakPolarHBondContact OD1-CE 3.17Å; D137-K157 IonicContact OD1-NZ 3.32Å; D137-K157 WeakPolarHBondContact OD2-CE 3.33Å; D137-K157 IonicContact OD2-NZ 2.77Å; D137-K157 PolarHBondContact OD2-NZ 2.67Å
158A66.3Low73.2Confident1 Ų143.8 Ų43.81%0.00824%0.239CC..  trans-60.7-178.217100000115.9R19 V26 A27 R28 W128 E132R19-A158 VanDerWaalsContact CZ-CA 3.4Å; V26-A158 CarbonylContact C-O 3.47Å; A27-A158 WeakPolarHBondContact CA-O 3.37Å; A27-A158 HydrophobicContact CB-CB 3.63Å; A27-A158 WeakPolarHBondContact CB-O 3.12Å; A27-A158 PolarHBondContact N-O 2.93Å; R28-A158 VanDerWaalsContact O-CB 3.24Å; R28-A158 WeakPolarHBondContact O-CB 3.23Å; W128-A158 HydrophobicContact CG-CB 4.36Å; E132-A158 HydrophobicContact CB-CB 4.32Å; E132-A158 PolarHBondContact O-N 3.21Å
159N62.3Low73.5Confident10 Ų1052.6 Ų52.65%0.05327%0.267CS..  trans-115.6128.6-175.5-166.1-30.5000112.6R24 V26 L161 E162 S163R24-N159 PolarHBondContact O-ND2 3.17Å; V26-N159 CarbonylContact O-C 3.6Å; V26-N159 WeakPolarHBondContact O-CA 3.15Å; N159-L161 PolarHBondContact O-N 3.08Å; N159-L161 PolarHBondContact OD1-N 3.12Å; N159-L161 VanDerWaalsContact OD1-N 3.17Å; N159-E162 CarbonylContact O-C 3.36Å; N159-E162 PolarHBondContact O-N 3.18Å; N159-S163 PolarHBondContact O-N 2.98Å; N159-S163 PolarHBondContact O-OG 2.62Å
160L54.9Low74.1Confident13 Ų1345.4 Ų45.47%0.06824%0.235CC..THydrogen-bonded Turntrans-66-28.2-171.7-84-160.2000111.1V26 R28 R32 L301V26-L160 VanDerWaalsContact C-CD2 3.45Å; V26-L160 HydrophobicContact CB-CD1 3.67Å; V26-L160 HydrophobicContact CB-CD2 3.97Å; V26-L160 HydrophobicContact CB-CG 3.5Å; V26-L160 HydrophobicContact CG1-CD1 3.71Å; V26-L160 HydrophobicContact CG1-CD2 3.56Å; V26-L160 HydrophobicContact CG1-CG 3.64Å; V26-L160 VanDerWaalsContact O-CA 3.22Å; V26-L160 WeakPolarHBondContact O-CA 3.47Å; V26-L160 VanDerWaalsContact O-CB 3.25Å; V26-L160 WeakPolarHBondContact O-CB 3.31Å; V26-L160 WeakPolarHBondContact O-CD2 3.29Å; V26-L160 WeakPolarHBondContact O-CG 3.48Å; V26-L160 PolarHBondContact O-N 3.03Å; R28-L160 HydrophobicContact CG-CD2 3.56Å; R32-L160 PolarHBondContact NH1-O 3.5Å; L160-L301 HydrophobicContact CD1-CD1 3.5Å; L160-L301 VanDerWaalsContact CD1-CD1 3.5Å; L160-L301 HydrophobicContact CD1-CD2 4.24Å
161L54.7Low74.8Confident86 Ų8639.1 Ų39.145%0.4520%0.202SC..THydrogen-bonded Turntrans-70.9-25.7177.7-63.5177.3000110.8N159 Y298N159-L161 PolarHBondContact O-N 3.08Å; N159-L161 PolarHBondContact OD1-N 3.12Å; N159-L161 VanDerWaalsContact OD1-N 3.17Å; L161-Y298 HydrophobicContact CD2-CE1 4.45Å
162E55.1Low75.6Confident17 Ų1739.5 Ų39.58%0.07920%0.202CC..THydrogen-bonded Turntrans-111.8-6.6-170.4-55.7-171.3156.300112.1K22 V31 R32 M33 N159K22-E162 IonicContact NZ-OE1 3.81Å; K22-E162 PolarHBondContact NZ-OE1 3.03Å; V31-E162 CarbonylContact C-O 3.49Å; V31-E162 VanDerWaalsContact CA-O 3.28Å; V31-E162 WeakPolarHBondContact CA-O 3.41Å; R32-E162 PolarHBondContact N-O 2.86Å; M33-E162 HydrophobicContact CE-CB 4.44Å; M33-E162 HydrophobicContact CE-CG 3.85Å; N159-E162 CarbonylContact O-C 3.36Å; N159-E162 PolarHBondContact O-N 3.18Å
163S58.5Low76.4Confident0 Ų037.9 Ų37.90%020%0.197CC..EExtended strand (participates in β ladder)trans-141.6161.5-172.456.90000115.6R28 G30 N159R28-S163 WeakPolarHBondContact CA-OG 3.13Å; R28-S163 WeakPolarHBondContact CB-O 3.46Å; R28-S163 WeakPolarHBondContact CB-OG 3.49Å; R28-S163 VanDerWaalsContact CD-O 3.31Å; R28-S163 WeakPolarHBondContact CD-O 3.26Å; R28-S163 PolarHBondContact N-OG 3.42Å; R28-S163 WeakPolarHBondContact O-CB 3.2Å; R28-S163 PolarHBondContact O-OG 2.97Å; G30-S163 CarbonylContact O-C 3.53Å; G30-S163 VanDerWaalsContact O-C 3.25Å; G30-S163 WeakPolarHBondContact O-CA 3.27Å; G30-S163 WeakPolarHBondContact O-CB 3.27Å; N159-S163 PolarHBondContact O-N 2.98Å; N159-S163 PolarHBondContact O-OG 2.62Å
164D68.1Low77.5Confident44 Ų4434.6 Ų34.624%0.23518%0.179CC..EExtended strand (participates in β ladder)trans-141.9149175.2-149.4-39.7000112.5R28 N29 G30 Y166R28-D164 VanDerWaalsContact CB-C 3.49Å; R28-D164 VanDerWaalsContact CB-N 3.27Å; R28-D164 IonicContact NH1-OD2 2.65Å; N29-D164 PolarHBondContact N-O 3.45Å; N29-D164 PolarHBondContact OD1-O 3.19Å; G30-D164 PolarHBondContact N-O 3.47Å; G30-D164 PolarHBondContact O-N 3.17Å; D164-Y166 HydrophobicContact CB-CD2 4.34Å; D164-Y166 HydrophobicContact CB-CE1 4.25Å; D164-Y166 HydrophobicContact CB-CE2 4.08Å; D164-Y166 PolarHBondContact OD1-N 3.17Å
165F71.7Confident78.3Confident17 Ų1734.5 Ų34.58%0.07518%0.179CC..  trans-90.3-6.8170.2-56.7-39.5000112.3A27 R28 N29 R133 W134 D135 G167 E168A27-F165 WeakPolarHBondContact O-CE1 3.16Å; A27-F165 VanDerWaalsContact O-CZ 3.23Å; A27-F165 WeakPolarHBondContact O-CZ 3.45Å; R28-F165 HydrophobicContact CB-CD1 3.73Å; R28-F165 HydrophobicContact CB-CE1 3.78Å; R28-F165 HydrophobicContact CB-CG 4.22Å; R28-F165 HydrophobicContact CB-CZ 4.33Å; R28-F165 HydrophobicContact CG-CD1 4Å; R28-F165 HydrophobicContact CG-CD2 4.1Å; R28-F165 HydrophobicContact CG-CE1 3.94Å; R28-F165 HydrophobicContact CG-CE2 4.11Å; R28-F165 HydrophobicContact CG-CG 4.07Å; R28-F165 HydrophobicContact CG-CZ 3.99Å; N29-F165 HydrophobicContact CB-CD1 4.44Å; R133-F165 HydrophobicContact CB-CE1 3.58Å; R133-F165 HydrophobicContact CB-CZ 3.74Å; R133-F165 HydrophobicContact CG-CD1 4.1Å; R133-F165 HydrophobicContact CG-CE1 3.36Å; R133-F165 HydrophobicContact CG-CZ 4Å; R133-F165 VanDerWaalsContact CZ-CE1 3.49Å; R133-F165 VanDerWaalsContact CZ-CG 3.49Å; R133-F165 VanDerWaalsContact NH2-CE2 3.27Å; R133-F165 VanDerWaalsContact NH2-CG 3.33Å; W134-F165 AromaticContact CD1-CE2 3.21Å; W134-F165 AromaticContact CD1-CZ 3.1Å; W134-F165 AromaticContact CE2-CE2 3.9Å; W134-F165 HydrophobicContact CG-CE2 4.17Å; W134-F165 AromaticContact CG-CZ 3.91Å; W134-F165 HydrophobicContact CG-CZ 3.91Å; W134-F165 AromaticContact NE1-CD2 3.92Å; W134-F165 AromaticContact NE1-CE2 2.98Å; W134-F165 AromaticContact NE1-CZ 3.46Å; D135-F165 HydrophobicContact CB-CE2 4.47Å; D135-F165 WeakPolarHBondContact OD1-CE2 3.48Å; D135-F165 WeakPolarHBondContact OD1-CZ 3.32Å; D135-F165 VanDerWaalsContact OD2-CE2 3.31Å; D135-F165 WeakPolarHBondContact OD2-CE2 3.31Å; F165-G167 PolarHBondContact O-N 3.42Å; F165-G167 VanDerWaalsContact O-N 3.14Å; F165-E168 WeakPolarHBondContact O-CB 3.27Å; F165-E168 PolarHBondContact O-N 2.89Å
166Y74.8Confident78.9Confident35 Ų3534.5 Ų34.514%0.13718%0.179CC..THydrogen-bonded Turntrans58.130-178.6-60.3-78.2000113V31 F127 D164 E168 K215 K218 M219V31-Y166 PolarHBondContact O-OH 3.46Å; F127-Y166 HydrophobicContact CE1-CD2 4.41Å; F127-Y166 HydrophobicContact CE1-CE2 4.22Å; F127-Y166 HydrophobicContact CZ-CE2 4.36Å; D164-Y166 HydrophobicContact CB-CD2 4.34Å; D164-Y166 HydrophobicContact CB-CE1 4.25Å; D164-Y166 HydrophobicContact CB-CE2 4.08Å; D164-Y166 PolarHBondContact OD1-N 3.17Å; Y166-E168 PolarHBondContact O-N 3.22Å; Y166-K215 HydrophobicContact CD2-CB 4.43Å; Y166-K218 HydrophobicContact CD1-CB 3.95Å; Y166-K218 HydrophobicContact CG-CB 4.09Å; Y166-K218 WeakPolarHBondContact O-CD 3.44Å; Y166-K218 PolarHBondContact O-NZ 3.33Å; Y166-M219 HydrophobicContact CD1-CB 4.49Å; Y166-M219 HydrophobicContact CD2-CB 4.48Å; Y166-M219 VanDerWaalsContact CE1-CA 3.49Å; Y166-M219 HydrophobicContact CE1-CB 3.84Å; Y166-M219 HydrophobicContact CE1-CG 4.26Å; Y166-M219 HydrophobicContact CE2-CB 3.8Å; Y166-M219 HydrophobicContact CE2-CG 4.16Å; Y166-M219 HydrophobicContact CE2-SD 3.99Å; Y166-M219 VanDerWaalsContact CZ-CB 3.45Å; Y166-M219 WeakPolarHBondContact OH-CG 3.5Å; Y166-M219 PolarHBondContact OH-SD 2.93Å
167G80.3Confident79.8Confident73 Ų7333.7 Ų33.775%0.75317%0.169SC*.THydrogen-bonded Turntrans69.516.7-177.800000114.5F165F165-G167 PolarHBondContact O-N 3.42Å; F165-G167 VanDerWaalsContact O-N 3.14Å
168E88.7Confident80.5Confident21 Ų2131.5 Ų31.510%0.09816%0.159CC..PPolyproline II helixtrans-93147.9178.6-64.4-66.1151.300112.4R133 F165 Y166 V211 R214 K215 K218R133-E168 PolarHBondContact NH1-O 3.19Å; R133-E168 PolarHBondContact NH2-O 3.03Å; R133-E168 VanDerWaalsContact NH2-O 3.14Å; F165-E168 WeakPolarHBondContact O-CB 3.27Å; F165-E168 PolarHBondContact O-N 2.89Å; Y166-E168 PolarHBondContact O-N 3.22Å; E168-V211 HydrophobicContact CB-CG1 3.74Å; E168-V211 HydrophobicContact CG-CG1 4.13Å; E168-R214 VanDerWaalsContact CD-NE 3.28Å; E168-R214 HydrophobicContact CG-CB 4.41Å; E168-R214 IonicContact OE1-NE 3.99Å; E168-R214 PolarHBondContact OE1-NE 3.32Å; E168-R214 VanDerWaalsContact OE1-NE 3.17Å; E168-R214 IonicContact OE2-CZ 2.86Å; E168-R214 VanDerWaalsContact OE2-CZ 3.28Å; E168-R214 IonicContact OE2-NE 3.53Å; E168-R214 PolarHBondContact OE2-NE 2.94Å; E168-R214 IonicContact OE2-NH2 2.9Å; E168-R214 PolarHBondContact OE2-NH2 3.31Å; E168-K215 HydrophobicContact CB-CG 4.06Å; E168-K215 HydrophobicContact CG-CG 3.85Å; E168-K218 WeakPolarHBondContact OE1-CE 3.34Å; E168-K218 IonicContact OE1-NZ 3.64Å; E168-K218 PolarHBondContact OE1-NZ 2.91Å
169R91.1Very high81.9Confident208 Ų20834.5 Ų34.579%0.78518%0.175SC*.PPolyproline II helixtrans-66.3164.2175.7-58.2-178.7-176.9-177.9-0.1110.9R133R133-R169 PolarHBondContact NH1-O 2.76Å
170Y93.3Very high83.5Confident14 Ų1434.7 Ų34.76%0.05518%0.177CC..PPolyproline II helixtrans-60.5137.5167.2-165.8-84.5000110.1E130 H131 R133 R136 Y139 I140 Y172 H177E130-Y170 HydrophobicContact CG-CE1 4.23Å; E130-Y170 HydrophobicContact CG-CE2 4.15Å; E130-Y170 VanDerWaalsContact O-CE2 3.3Å; E130-Y170 WeakPolarHBondContact O-CE2 3.13Å; H131-Y170 WeakPolarHBondContact CA-OH 3.26Å; R133-Y170 HydrophobicContact CB-CD2 4.38Å; R133-Y170 HydrophobicContact CB-CE2 4.26Å; R133-Y170 HydrophobicContact CG-CD2 4.45Å; R133-Y170 HydrophobicContact CG-CE2 4.42Å; R136-Y170 HydrophobicContact CB-CD2 4.5Å; R136-Y170 HydrophobicContact CB-CE2 3.74Å; Y139-Y170 HydrophobicContact CD1-CD1 4.33Å; Y139-Y170 HydrophobicContact CD1-CG 4.04Å; Y139-Y170 VanDerWaalsContact CD2-CB 3.41Å; Y139-Y170 HydrophobicContact CD2-CD1 4.41Å; Y139-Y170 AromaticContact CD2-CD2 3.58Å; Y139-Y170 HydrophobicContact CD2-CD2 3.58Å; Y139-Y170 HydrophobicContact CD2-CE2 4.48Å; Y139-Y170 AromaticContact CD2-CG 3.55Å; Y139-Y170 HydrophobicContact CD2-CG 3.55Å; Y139-Y170 HydrophobicContact CE2-CD2 4.28Å; Y139-Y170 HydrophobicContact CE2-CG 4.16Å; Y139-Y170 VanDerWaalsContact CG-CB 3.45Å; Y139-Y170 AromaticContact CG-CD1 3.9Å; Y139-Y170 HydrophobicContact CG-CD1 3.9Å; Y139-Y170 AromaticContact CG-CD2 3.91Å; Y139-Y170 HydrophobicContact CG-CD2 3.91Å; Y139-Y170 AromaticContact CG-CG 3.47Å; Y139-Y170 HydrophobicContact CG-CG 3.47Å; Y139-Y170 VanDerWaalsContact CG-CG 3.47Å; I140-Y170 WeakPolarHBondContact CD1-OH 3.42Å; I140-Y170 HydrophobicContact CG2-CE1 4.23Å; Y170-Y172 HydrophobicContact CD1-CD1 4.14Å; Y170-Y172 HydrophobicContact CD1-CE1 4.07Å; Y170-Y172 HydrophobicContact CD1-CE2 4.44Å; Y170-Y172 HydrophobicContact CD1-CG 4.37Å; Y170-Y172 AromaticContact CE1-CD1 3.83Å; Y170-Y172 HydrophobicContact CE1-CD1 3.83Å; Y170-Y172 AromaticContact CE1-CE1 3.89Å; Y170-Y172 HydrophobicContact CE1-CE1 3.89Å; Y170-Y172 HydrophobicContact CE1-CG 4.41Å; Y170-H177 AromaticContact CE1-CD2 3.72Å; Y170-H177 AromaticContact CE1-NE2 3.54Å; Y170-H177 AromaticContact CZ-CD2 3.81Å; Y170-H177 AromaticContact CZ-NE2 3.5Å; Y170-H177 PolarHBondContact OH-CD2 2.88Å; Y170-H177 VanDerWaalsContact OH-CD2 3.27Å; Y170-H177 PolarHBondContact OH-NE2 2.77Å
171D96Very high85.4Confident10 Ų1039.3 Ų39.35%0.05320%0.197CC..  trans-123.298.2-173.4-177.727.2000113E130 F173 S174 S209 V211E130-D171 PolarHBondContact OE1-N 3.06Å; D171-F173 PolarHBondContact O-N 2.96Å; D171-F173 VanDerWaalsContact O-N 3.17Å; D171-F173 WeakPolarHBondContact OD1-CA 3.31Å; D171-F173 WeakPolarHBondContact OD1-CB 3.18Å; D171-F173 PolarHBondContact OD1-N 3.07Å; D171-S174 VanDerWaalsContact CG-N 3.32Å; D171-S174 VanDerWaalsContact O-CB 3.31Å; D171-S174 WeakPolarHBondContact O-CB 3.49Å; D171-S174 PolarHBondContact O-N 3.3Å; D171-S174 VanDerWaalsContact OD2-CA 3.26Å; D171-S174 WeakPolarHBondContact OD2-CA 3.36Å; D171-S174 WeakPolarHBondContact OD2-CB 3.27Å; D171-S174 PolarHBondContact OD2-N 3.46Å; D171-S174 VanDerWaalsContact OD2-N 3.12Å; D171-S209 WeakPolarHBondContact OD2-CB 3.35Å; D171-S209 PolarHBondContact OD2-OG 3.26Å; D171-V211 HydrophobicContact CB-CB 3.91Å; D171-V211 HydrophobicContact CB-CG1 3.98Å; D171-V211 HydrophobicContact CB-CG2 3.97Å; D171-V211 WeakPolarHBondContact OD2-CB 3.42Å
172Y96.4Very high87.1Confident15 Ų1535.8 Ų35.86%0.05918%0.179CC..THydrogen-bonded Turntrans-62.1-19.9173.3-58.5-76.3000113.2Y139 I140 Y170 A193 Q195 M198 I202Y139-Y172 WeakPolarHBondContact CA-OH 2.96Å; Y139-Y172 WeakPolarHBondContact CB-OH 3.25Å; Y139-Y172 WeakPolarHBondContact O-CE1 3.45Å; Y139-Y172 PolarHBondContact O-OH 3Å; I140-Y172 HydrophobicContact CG2-CE1 3.95Å; Y170-Y172 HydrophobicContact CD1-CD1 4.14Å; Y170-Y172 HydrophobicContact CD1-CE1 4.07Å; Y170-Y172 HydrophobicContact CD1-CE2 4.44Å; Y170-Y172 HydrophobicContact CD1-CG 4.37Å; Y170-Y172 AromaticContact CE1-CD1 3.83Å; Y170-Y172 HydrophobicContact CE1-CD1 3.83Å; Y170-Y172 AromaticContact CE1-CE1 3.89Å; Y170-Y172 HydrophobicContact CE1-CE1 3.89Å; Y170-Y172 HydrophobicContact CE1-CG 4.41Å; Y172-A193 HydrophobicContact CD1-CB 4.05Å; Y172-A193 HydrophobicContact CE1-CB 3.62Å; Y172-Q195 HydrophobicContact CE2-CB 3.94Å; Y172-M198 HydrophobicContact CD1-CB 3.9Å; Y172-M198 HydrophobicContact CD1-CG 4.4Å; Y172-M198 HydrophobicContact CD2-CB 4.2Å; Y172-M198 HydrophobicContact CD2-CG 3.78Å; Y172-M198 HydrophobicContact CD2-SD 4.13Å; Y172-M198 HydrophobicContact CE1-CB 4.26Å; Y172-M198 HydrophobicContact CE2-CG 4.16Å; Y172-M198 HydrophobicContact CG-CB 3.85Å; Y172-M198 HydrophobicContact CG-CG 3.9Å; Y172-M198 HydrophobicContact CG-SD 4.17Å; Y172-I202 HydrophobicContact CD1-CG2 3.76Å; Y172-I202 HydrophobicContact CG-CG2 4.36Å
173F96.5Very high88.7Confident59 Ų5938.4 Ų38.426%0.25919%0.191SC..THydrogen-bonded Turntrans-96.214.3176.5-55.6-92.6000111.9D171 M198 I201 M205 S209 L238D171-F173 PolarHBondContact O-N 2.96Å; D171-F173 VanDerWaalsContact O-N 3.17Å; D171-F173 WeakPolarHBondContact OD1-CA 3.31Å; D171-F173 WeakPolarHBondContact OD1-CB 3.18Å; D171-F173 PolarHBondContact OD1-N 3.07Å; F173-M198 HydrophobicContact CE2-CE 4.41Å; F173-M198 HydrophobicContact CE2-SD 3.84Å; F173-M198 HydrophobicContact CZ-CE 3.99Å; F173-M198 HydrophobicContact CZ-SD 3.83Å; F173-I201 HydrophobicContact CD1-CG2 3.59Å; F173-I201 HydrophobicContact CE1-CG2 3.43Å; F173-I201 VanDerWaalsContact CE1-CG2 3.43Å; F173-I201 HydrophobicContact CG-CG2 4.35Å; F173-I201 HydrophobicContact CZ-CG2 4.06Å; F173-M205 VanDerWaalsContact C-CG 3.49Å; F173-M205 HydrophobicContact CB-CE 4.31Å; F173-M205 HydrophobicContact CB-CG 4.15Å; F173-M205 HydrophobicContact CB-SD 4.06Å; F173-M205 HydrophobicContact CD1-CE 3.64Å; F173-M205 HydrophobicContact CD1-SD 3.89Å; F173-M205 HydrophobicContact CE1-CE 4.47Å; F173-M205 HydrophobicContact CG-CE 4.38Å; F173-M205 HydrophobicContact CG-SD 4.49Å; F173-M205 WeakPolarHBondContact O-CG 3.44Å; F173-S209 WeakPolarHBondContact O-CB 3.31Å; F173-L238 HydrophobicContact CD1-CD2 3.75Å; F173-L238 HydrophobicContact CE1-CD2 4.15Å; F173-L238 HydrophobicContact CG-CD2 4.41Å
174S96.9Very high90.4Very high0 Ų040.4 Ų40.40%020%0.203CC..  trans-69.7137.1177.5-178.50000109.8D171 M176 H177 D212D171-S174 VanDerWaalsContact CG-N 3.32Å; D171-S174 VanDerWaalsContact O-CB 3.31Å; D171-S174 WeakPolarHBondContact O-CB 3.49Å; D171-S174 PolarHBondContact O-N 3.3Å; D171-S174 VanDerWaalsContact OD2-CA 3.26Å; D171-S174 WeakPolarHBondContact OD2-CA 3.36Å; D171-S174 WeakPolarHBondContact OD2-CB 3.27Å; D171-S174 PolarHBondContact OD2-N 3.46Å; D171-S174 VanDerWaalsContact OD2-N 3.12Å; S174-M176 PolarHBondContact O-N 3.13Å; S174-M176 WeakPolarHBondContact OG-CB 3.47Å; S174-M176 PolarHBondContact OG-N 3.22Å; S174-M176 VanDerWaalsContact OG-N 3.08Å; S174-H177 WeakPolarHBondContact O-CB 3.45Å; S174-H177 PolarHBondContact O-N 2.88Å; S174-H177 VanDerWaalsContact O-N 3.11Å; S174-D212 WeakPolarHBondContact CA-OD2 3.3Å; S174-D212 WeakPolarHBondContact CB-OD1 3.15Å; S174-D212 PolarHBondContact OG-OD1 3.13Å
175I96.6Very high91.7Very high12 Ų1245.8 Ų45.86%0.06222%0.22CC..THydrogen-bonded Turntrans-63.4-17.9169.1-164.5156.8000111.7D115 I118 H119 M122 H177 F208 D212D115-I175 HydrophobicContact CB-CD1 4.18Å; I118-I175 HydrophobicContact CB-CD1 3.94Å; I118-I175 HydrophobicContact CG2-CD1 3.7Å; I118-I175 HydrophobicContact CG2-CG2 4.37Å; H119-I175 HydrophobicContact CB-CG1 4.43Å; H119-I175 PolarHBondContact CE1-O 2.79Å; H119-I175 PolarHBondContact ND1-O 2.65Å; M122-I175 HydrophobicContact SD-CG2 3.8Å; I175-H177 VanDerWaalsContact C-N 3.34Å; I175-F208 HydrophobicContact CG2-CD1 4.43Å; I175-D212 PolarHBondContact N-OD2 3.35Å
176M96.2Very high92.8Very high0 Ų048.1 Ų48.10%023%0.233CC..THydrogen-bonded Turntrans-89.38.5176.6-53.4-50.6-62.800113.6M122 H123 H129 E130 S174M122-M176 HydrophobicContact CB-CE 4.33Å; M122-M176 HydrophobicContact CB-SD 3.54Å; M122-M176 VanDerWaalsContact CB-SD 3.54Å; M122-M176 HydrophobicContact CE-CG 3.69Å; M122-M176 HydrophobicContact CG-CG 4.16Å; M122-M176 HydrophobicContact CG-SD 3.83Å; M122-M176 HydrophobicContact SD-CG 3.49Å; M122-M176 WeakPolarHBondContact SD-CG 3.38Å; M122-M176 HydrophobicContact SD-SD 3.66Å; M122-M176 VanDerWaalsContact SD-SD 3.66Å; H123-M176 WeakPolarHBondContact CE1-CE 3.42Å; H123-M176 VanDerWaalsContact ND1-CE 3.32Å; H123-M176 WeakPolarHBondContact ND1-CE 3.15Å; H129-M176 CarbonylContact C-O 3.51Å; H129-M176 WeakPolarHBondContact CA-O 3.47Å; H129-M176 WeakPolarHBondContact CB-O 3.39Å; H129-M176 PolarHBondContact CD2-O 3.24Å; E130-M176 PolarHBondContact N-O 2.98Å; S174-M176 PolarHBondContact O-N 3.13Å; S174-M176 WeakPolarHBondContact OG-CB 3.47Å; S174-M176 PolarHBondContact OG-N 3.22Å; S174-M176 VanDerWaalsContact OG-N 3.08Å
177H97Very high93.8Very high5 Ų548.6 Ų48.62%0.02325%0.249CC..PPolyproline II helixtrans-92.9133.8177.7-159.1-55.2000110.7E130 Y170 S174 I175 G203E130-H177 HydrophobicContact CB-CB 4.01Å; Y170-H177 AromaticContact CE1-CD2 3.72Å; Y170-H177 AromaticContact CE1-NE2 3.54Å; Y170-H177 AromaticContact CZ-CD2 3.81Å; Y170-H177 AromaticContact CZ-NE2 3.5Å; Y170-H177 PolarHBondContact OH-CD2 2.88Å; Y170-H177 VanDerWaalsContact OH-CD2 3.27Å; Y170-H177 PolarHBondContact OH-NE2 2.77Å; S174-H177 WeakPolarHBondContact O-CB 3.45Å; S174-H177 PolarHBondContact O-N 2.88Å; S174-H177 VanDerWaalsContact O-N 3.11Å; I175-H177 VanDerWaalsContact C-N 3.34Å; H177-G203 WeakPolarHBondContact O-CA 3.48Å; H177-G203 PolarHBondContact O-N 2.93Å
178Y94.9Very high94.6Very high21 Ų2153.1 Ų53.18%0.08224%0.243CC..PPolyproline II helixtrans-62.4153.5168.9-80.1-2.1000113.8Q8 H129 H131 A182 F183 I202 G203Q8-Y178 WeakPolarHBondContact CA-OH 3.4Å; Q8-Y178 VanDerWaalsContact CB-OH 3.26Å; Q8-Y178 WeakPolarHBondContact CB-OH 3.25Å; Q8-Y178 PolarHBondContact O-OH 3.37Å; H129-Y178 AromaticContact CD2-CD1 3.86Å; H129-Y178 AromaticContact CD2-CE1 3.56Å; H129-Y178 AromaticContact CE1-CE1 3.41Å; H129-Y178 VanDerWaalsContact CE1-CE1 3.41Å; H129-Y178 WeakPolarHBondContact CE1-CE1 3.26Å; H129-Y178 AromaticContact CE1-CZ 3.76Å; H129-Y178 AromaticContact CG-CE1 3.9Å; H129-Y178 AromaticContact ND1-CE1 3.81Å; H129-Y178 AromaticContact ND1-CZ 3.96Å; H129-Y178 AromaticContact NE2-CD1 3.94Å; H129-Y178 AromaticContact NE2-CE1 3.22Å; H129-Y178 WeakPolarHBondContact NE2-CE1 3.08Å; H131-Y178 AromaticContact CD2-CD2 3.99Å; H131-Y178 AromaticContact CE1-CD1 3.76Å; H131-Y178 AromaticContact CE1-CD2 3.09Å; H131-Y178 WeakPolarHBondContact CE1-CD2 3.47Å; H131-Y178 AromaticContact CE1-CE1 3.86Å; H131-Y178 AromaticContact CE1-CE2 3.15Å; H131-Y178 WeakPolarHBondContact CE1-CE2 2.91Å; H131-Y178 AromaticContact CE1-CG 3.4Å; H131-Y178 AromaticContact CE1-CZ 3.56Å; H131-Y178 AromaticContact ND1-CD2 3.63Å; H131-Y178 AromaticContact ND1-CG 3.57Å; H131-Y178 AromaticContact NE2-CD2 3.34Å; H131-Y178 VanDerWaalsContact NE2-CD2 3.34Å; H131-Y178 WeakPolarHBondContact NE2-CD2 3.32Å; H131-Y178 AromaticContact NE2-CE2 3.31Å; H131-Y178 VanDerWaalsContact NE2-CE2 3.31Å; H131-Y178 WeakPolarHBondContact NE2-CE2 3.28Å; Y178-A182 HydrophobicContact CD2-CB 3.71Å; Y178-A182 HydrophobicContact CE2-CB 4.4Å; Y178-A182 HydrophobicContact CG-CB 4.01Å; Y178-F183 HydrophobicContact CD2-CE2 4.33Å; Y178-F183 HydrophobicContact CE2-CD2 4.07Å; Y178-F183 AromaticContact CE2-CE2 3.49Å; Y178-F183 HydrophobicContact CE2-CE2 3.49Å; Y178-F183 VanDerWaalsContact CE2-CE2 3.49Å; Y178-F183 AromaticContact CZ-CE2 3.76Å; Y178-I202 CarbonylContact O-C 3.38Å; Y178-G203 PolarHBondContact O-N 2.88Å
179D95.3Very high95Very high65 Ų6555.9 Ų55.935%0.34825%0.253SS..PPolyproline II helixtrans-71.5164.2167.874.475.1000112K181 A182D179-K181 PolarHBondContact O-N 3.29Å; D179-K181 VanDerWaalsContact O-N 3.12Å; D179-K181 WeakPolarHBondContact OD1-CA 3.49Å; D179-K181 PolarHBondContact OD1-N 3.34Å; D179-A182 PolarHBondContact O-N 2.79Å; D179-A182 PolarHBondContact OD1-N 2.86Å
180S97Very high95.2Very high13 Ų1346 Ų469%0.09122%0.215CC..THydrogen-bonded Turntrans-67.5-10.2-17560.10000115.1R189 T190 I191 T199S180-R189 CarbonylContact O-C 3.58Å; S180-R189 WeakPolarHBondContact O-CA 3.48Å; S180-R189 WeakPolarHBondContact O-CB 3.17Å; S180-T190 PolarHBondContact O-N 3Å; S180-T190 PolarHBondContact O-OG1 3.14Å; S180-I191 WeakPolarHBondContact CB-O 3.35Å; S180-I191 PolarHBondContact O-N 2.83Å; S180-T199 WeakPolarHBondContact CB-O 3.46Å
181K94.8Very high95.4Very high111 Ų11145.3 Ų45.348%0.48321%0.213SC..THydrogen-bonded Turntrans-117.98.3-177.6-64.8-174.9-179.7-176.80113.3D179 F183 T184D179-K181 PolarHBondContact O-N 3.29Å; D179-K181 VanDerWaalsContact O-N 3.12Å; D179-K181 WeakPolarHBondContact OD1-CA 3.49Å; D179-K181 PolarHBondContact OD1-N 3.34Å; K181-F183 PolarHBondContact O-N 3.36Å; K181-T184 HydrophobicContact CB-CG2 4.25Å; K181-T184 VanDerWaalsContact O-CB 3.29Å; K181-T184 WeakPolarHBondContact O-CB 3.47Å; K181-T184 WeakPolarHBondContact O-CG2 3.23Å; K181-T184 PolarHBondContact O-N 3.35Å; K181-T184 VanDerWaalsContact O-N 3.1Å
182A90.1Very high95.5Very high11 Ų1148.2 Ų48.29%0.09123%0.226CC..THydrogen-bonded Turntrans-48.6130.117700000110.9F155 Y178 D179 T184 T190F155-A182 HydrophobicContact CZ-CB 4.5Å; F155-A182 WeakPolarHBondContact CZ-O 3.34Å; Y178-A182 HydrophobicContact CD2-CB 3.71Å; Y178-A182 HydrophobicContact CE2-CB 4.4Å; Y178-A182 HydrophobicContact CG-CB 4.01Å; D179-A182 PolarHBondContact O-N 2.79Å; D179-A182 PolarHBondContact OD1-N 2.86Å; A182-T184 PolarHBondContact O-N 2.88Å; A182-T184 VanDerWaalsContact O-N 3.12Å; A182-T190 PolarHBondContact N-OG1 3.19Å; A182-T190 WeakPolarHBondContact O-CB 3.02Å; A182-T190 VanDerWaalsContact O-CG2 3.27Å; A182-T190 WeakPolarHBondContact O-CG2 3.28Å; A182-T190 PolarHBondContact O-OG1 3.34Å
183F89.5Confident95.6Very high72 Ų7248.1 Ų48.132%0.31623%0.228SC..THydrogen-bonded Turntrans54.826.9179.1-54-85.2000116.1I147 A148 A151 Q154 F155 Y178 K181I147-F183 HydrophobicContact CG2-CB 4.42Å; A148-F183 PolarHBondContact N-O 2.69Å; A151-F183 HydrophobicContact CB-CB 3.71Å; A151-F183 HydrophobicContact CB-CD1 3.72Å; A151-F183 HydrophobicContact CB-CG 3.91Å; Q154-F183 HydrophobicContact CB-CD2 4.04Å; Q154-F183 HydrophobicContact CB-CE1 4.36Å; Q154-F183 HydrophobicContact CB-CE2 3.89Å; Q154-F183 HydrophobicContact CB-CG 4.37Å; Q154-F183 HydrophobicContact CB-CZ 4.04Å; Q154-F183 HydrophobicContact CG-CD1 4.18Å; Q154-F183 HydrophobicContact CG-CE1 3.92Å; Q154-F183 HydrophobicContact CG-CE2 4.35Å; Q154-F183 HydrophobicContact CG-CG 4.49Å; Q154-F183 HydrophobicContact CG-CZ 4.02Å; F155-F183 HydrophobicContact CE2-CB 3.92Å; F155-F183 AromaticContact CE2-CD2 3.92Å; F155-F183 HydrophobicContact CE2-CD2 3.92Å; F155-F183 HydrophobicContact CE2-CG 4.25Å; F155-F183 HydrophobicContact CZ-CB 4.3Å; F155-F183 HydrophobicContact CZ-CD2 4.1Å; Y178-F183 HydrophobicContact CD2-CE2 4.33Å; Y178-F183 HydrophobicContact CE2-CD2 4.07Å; Y178-F183 AromaticContact CE2-CE2 3.49Å; Y178-F183 HydrophobicContact CE2-CE2 3.49Å; Y178-F183 VanDerWaalsContact CE2-CE2 3.49Å; Y178-F183 AromaticContact CZ-CE2 3.76Å; K181-F183 PolarHBondContact O-N 3.36Å
184T94.3Very high95.7Very high42 Ų4249.1 Ų49.126%0.25824%0.239SC..BIsolated β-bridgetrans-65.4136.1177-173.90000112.5N146 K181 A182 N186 G187 R188N146-T184 CarbonylContact O-C 3.58Å; N146-T184 WeakPolarHBondContact O-CA 3.15Å; K181-T184 HydrophobicContact CB-CG2 4.25Å; K181-T184 VanDerWaalsContact O-CB 3.29Å; K181-T184 WeakPolarHBondContact O-CB 3.47Å; K181-T184 WeakPolarHBondContact O-CG2 3.23Å; K181-T184 PolarHBondContact O-N 3.35Å; K181-T184 VanDerWaalsContact O-N 3.1Å; A182-T184 PolarHBondContact O-N 2.88Å; A182-T184 VanDerWaalsContact O-N 3.12Å; T184-N186 PolarHBondContact OG1-N 3.49Å; T184-N186 PolarHBondContact OG1-OD1 2.72Å; T184-G187 PolarHBondContact OG1-N 3.38Å; T184-R188 VanDerWaalsContact CB-O 3.25Å; T184-R188 WeakPolarHBondContact CB-O 3.09Å; T184-R188 PolarHBondContact OG1-N 3.13Å; T184-R188 PolarHBondContact OG1-O 3.15Å
185R93.6Very high95.7Very high158 Ų15853.8 Ų53.860%0.59626%0.261SS*.SBendtrans-90.1-13.4174.176.7-176.7176.3124-1.9114E145 N146 A148E145-R185 PolarHBondContact O-NE 3.07Å; E145-R185 PolarHBondContact O-NH2 2.81Å; N146-R185 WeakPolarHBondContact O-CG 3.32Å; N146-R185 PolarHBondContact O-N 2.95Å; A148-R185 HydrophobicContact CB-CB 4.25Å
186N96.4Very high95.6Very high65 Ų6558.9 Ų58.935%0.34830%0.295SS..SBendtrans-137.911.5-168.962.112.3000113.3N146 T184 R188N146-N186 PolarHBondContact OD1-ND2 2.95Å; T184-N186 PolarHBondContact OG1-N 3.49Å; T184-N186 PolarHBondContact OG1-OD1 2.72Å; N186-R188 PolarHBondContact O-N 2.92Å; N186-R188 WeakPolarHBondContact OD1-CB 3.34Å; N186-R188 WeakPolarHBondContact OD1-CG 3.41Å; N186-R188 PolarHBondContact OD1-N 2.97Å
187G94.3Very high95.6Very high45 Ų4561.5 Ų61.546%0.46432%0.322SS..SBendtrans73.7-1.1-179.100000114.8T184T184-G187 PolarHBondContact OG1-N 3.38Å
188R97.3Very high95.6Very high168 Ų16862.6 Ų62.663%0.63433%0.327SS*.SBendtrans-87164.2175.7-55.6-178.4174.7-179.4-3.5110.5T184 N186T184-R188 VanDerWaalsContact CB-O 3.25Å; T184-R188 WeakPolarHBondContact CB-O 3.09Å; T184-R188 PolarHBondContact OG1-N 3.13Å; T184-R188 PolarHBondContact OG1-O 3.15Å; N186-R188 PolarHBondContact O-N 2.92Å; N186-R188 WeakPolarHBondContact OD1-CB 3.34Å; N186-R188 WeakPolarHBondContact OD1-CG 3.41Å; N186-R188 PolarHBondContact OD1-N 2.97Å
189R97.3Very high95.7Very high79 Ų7962.3 Ų62.330%0.29833%0.328SS..  trans-61.5140.5179.6-66.7176.4173.8160.7-4111.2L143 N146 S180 E192 D200L143-R189 HydrophobicContact CD1-CB 4.35Å; L143-R189 WeakPolarHBondContact CD1-O 3.45Å; N146-R189 VanDerWaalsContact CB-O 3.25Å; N146-R189 WeakPolarHBondContact CB-O 3.48Å; N146-R189 PolarHBondContact ND2-O 3.14Å; S180-R189 CarbonylContact O-C 3.58Å; S180-R189 WeakPolarHBondContact O-CA 3.48Å; S180-R189 WeakPolarHBondContact O-CB 3.17Å; R189-E192 HydrophobicContact CB-CG 4.38Å; R189-D200 IonicContact CZ-OD1 3.91Å; R189-D200 VanDerWaalsContact NH2-CG 3.28Å; R189-D200 IonicContact NH2-OD1 3.65Å; R189-D200 PolarHBondContact NH2-OD1 2.9Å; R189-D200 IonicContact NH2-OD2 3.68Å; R189-D200 PolarHBondContact NH2-OD2 3.34Å; R189-D200 VanDerWaalsContact NH2-OD2 3.16Å
190T96.4Very high95.7Very high0 Ų064.1 Ų64.10%034%0.337CS..SBendtrans-105.5-22.6171.751.60000111.7L143 N146 I147 S180 A182L143-T190 PolarHBondContact N-O 2.83Å; N146-T190 HydrophobicContact CB-CG2 4.17Å; I147-T190 HydrophobicContact CB-CG2 4.4Å; I147-T190 HydrophobicContact CG1-CG2 3.57Å; S180-T190 PolarHBondContact O-N 3Å; S180-T190 PolarHBondContact O-OG1 3.14Å; A182-T190 PolarHBondContact N-OG1 3.19Å; A182-T190 WeakPolarHBondContact O-CB 3.02Å; A182-T190 VanDerWaalsContact O-CG2 3.27Å; A182-T190 WeakPolarHBondContact O-CG2 3.28Å; A182-T190 PolarHBondContact O-OG1 3.34Å
191I97.7Very high95.6Very high0 Ų065.2 Ų65.20%034%0.342CS..EExtended strand (participates in β ladder)trans-125.6130.2174.7-52178.9000109.2H131 I140 N141 I142 F155 S180 I202H131-I191 HydrophobicContact CB-CD1 4.2Å; I140-I191 HydrophobicContact CB-CG2 3.82Å; I140-I191 HydrophobicContact CD1-CG2 3.81Å; I140-I191 HydrophobicContact CG1-CG2 4.39Å; I140-I191 HydrophobicContact CG2-CG2 3.94Å; N141-I191 WeakPolarHBondContact O-CA 3.31Å; I142-I191 HydrophobicContact CD1-CG1 4.01Å; I142-I191 HydrophobicContact CD1-CG2 4.45Å; F155-I191 HydrophobicContact CD1-CG1 4.46Å; F155-I191 HydrophobicContact CE1-CD1 3.93Å; F155-I191 HydrophobicContact CE1-CG1 3.77Å; S180-I191 WeakPolarHBondContact CB-O 3.35Å; S180-I191 PolarHBondContact O-N 2.83Å; I191-I202 HydrophobicContact CB-CD1 3.93Å; I191-I202 HydrophobicContact CG2-CD1 3.65Å
192E98Very high95.7Very high72 Ų7259.9 Ų59.934%0.33632%0.319SS..EExtended strand (participates in β ladder)trans-121.1128.9169.2-69.6-169.1154.700110.7I140 N141 L143 R189 T199I140-E192 CarbonylContact C-O 3.2Å; I140-E192 VanDerWaalsContact CA-O 3.22Å; I140-E192 WeakPolarHBondContact CA-O 3.31Å; N141-E192 HydrophobicContact CB-CB 4.48Å; N141-E192 PolarHBondContact N-O 2.91Å; N141-E192 PolarHBondContact O-N 2.81Å; L143-E192 HydrophobicContact CD1-CG 3.73Å; L143-E192 HydrophobicContact CG-CG 4.31Å; R189-E192 HydrophobicContact CB-CG 4.38Å; E192-T199 HydrophobicContact CG-CG2 4.4Å
193A98.1Very high95.8Very high13 Ų1360.8 Ų60.811%0.10733%0.329CS..EExtended strand (participates in β ladder)trans-75137.817400000110.9Y172 Q195 M198 T199Y172-A193 HydrophobicContact CD1-CB 4.05Å; Y172-A193 HydrophobicContact CE1-CB 3.62Å; A193-Q195 VanDerWaalsContact C-N 3.29Å; A193-M198 HydrophobicContact CB-CB 3.54Å; A193-T199 PolarHBondContact N-OG1 3.38Å
194V97.7Very high96Very high80 Ų8061.7 Ų61.749%0.48533%0.334SS..SBendtrans-66.5-36.2172.4174.40000110.2Y139 P196Y139-V194 WeakPolarHBondContact O-CB 3.33Å; Y139-V194 WeakPolarHBondContact O-CG2 3.43Å; Y139-V194 PolarHBondContact O-N 2.85Å; V194-P196 WeakPolarHBondContact O-CD 3.25Å
195Q96.4Very high96Very high97 Ų9760.7 Ų60.745%0.45333%0.327SS..SBendtrans-74.3124.3176.4-176.3172-5.600111Y172 A193 G197 M198Y172-Q195 HydrophobicContact CE2-CB 3.94Å; A193-Q195 VanDerWaalsContact C-N 3.29Å; Q195-G197 PolarHBondContact O-N 3.02Å; Q195-M198 HydrophobicContact CB-CB 4.3Å; Q195-M198 HydrophobicContact CB-CG 3.77Å; Q195-M198 HydrophobicContact CG-CG 3.73Å; Q195-M198 WeakPolarHBondContact O-CB 3.22Å; Q195-M198 PolarHBondContact O-N 3.25Å; Q195-M198 VanDerWaalsContact O-N 3.16Å
196P95.6Very high95.9Very high120 Ų12059.3 Ų59.378%0.77933%0.325SS*.THydrogen-bonded Turntrans-54.5135.4179.1-27.835.5000112.9V194 M198V194-P196 WeakPolarHBondContact O-CD 3.25Å; P196-M198 VanDerWaalsContact C-N 3.25Å; P196-M198 PolarHBondContact O-N 3.39Å
197G95.1Very high95.9Very high55 Ų5557.9 Ų57.957%0.56732%0.317SS*.THydrogen-bonded Turntrans80.6-12.6179.700000115.4Q195 I201Q195-G197 PolarHBondContact O-N 3.02Å; G197-I201 WeakPolarHBondContact O-CG1 3.21Å
198M97.2Very high96Very high28 Ų2856.7 Ų56.714%0.13830%0.299CS..G310 helixtrans-78.1-20.6-178.1-68.2-63120.200113.7Y172 F173 A193 Q195 P196 D200 I201 I202Y172-M198 HydrophobicContact CD1-CB 3.9Å; Y172-M198 HydrophobicContact CD1-CG 4.4Å; Y172-M198 HydrophobicContact CD2-CB 4.2Å; Y172-M198 HydrophobicContact CD2-CG 3.78Å; Y172-M198 HydrophobicContact CD2-SD 4.13Å; Y172-M198 HydrophobicContact CE1-CB 4.26Å; Y172-M198 HydrophobicContact CE2-CG 4.16Å; Y172-M198 HydrophobicContact CG-CB 3.85Å; Y172-M198 HydrophobicContact CG-CG 3.9Å; Y172-M198 HydrophobicContact CG-SD 4.17Å; F173-M198 HydrophobicContact CE2-CE 4.41Å; F173-M198 HydrophobicContact CE2-SD 3.84Å; F173-M198 HydrophobicContact CZ-CE 3.99Å; F173-M198 HydrophobicContact CZ-SD 3.83Å; A193-M198 HydrophobicContact CB-CB 3.54Å; Q195-M198 HydrophobicContact CB-CB 4.3Å; Q195-M198 HydrophobicContact CB-CG 3.77Å; Q195-M198 HydrophobicContact CG-CG 3.73Å; Q195-M198 WeakPolarHBondContact O-CB 3.22Å; Q195-M198 PolarHBondContact O-N 3.25Å; Q195-M198 VanDerWaalsContact O-N 3.16Å; P196-M198 VanDerWaalsContact C-N 3.25Å; P196-M198 PolarHBondContact O-N 3.39Å; M198-D200 VanDerWaalsContact C-N 3.25Å; M198-D200 PolarHBondContact O-N 2.81Å; M198-I201 WeakPolarHBondContact O-CB 3.26Å; M198-I201 PolarHBondContact O-N 3.23Å; M198-I201 HydrophobicContact SD-CB 4.44Å; M198-I201 HydrophobicContact SD-CG2 4.39Å; M198-I202 PolarHBondContact O-N 2.93Å; M198-I202 VanDerWaalsContact O-N 3.09Å
199T97.8Very high95.9Very high15 Ų1549.2 Ų49.29%0.09227%0.273CS..G310 helixtrans-60.8-32.7-179.4-54.50000113.3S180 E192 A193 I201 I202S180-T199 WeakPolarHBondContact CB-O 3.46Å; E192-T199 HydrophobicContact CG-CG2 4.4Å; A193-T199 PolarHBondContact N-OG1 3.38Å; T199-I201 VanDerWaalsContact C-N 3.33Å; T199-I202 VanDerWaalsContact O-CG1 3.31Å; T199-I202 WeakPolarHBondContact O-CG1 3.49Å
200D94.7Very high95.7Very high103 Ų10347.8 Ų47.855%0.55128%0.278SS*.G310 helixtrans-89.3-2.8178-62.9-49.4000112.7R189 M198 Q204R189-D200 IonicContact CZ-OD1 3.91Å; R189-D200 VanDerWaalsContact NH2-CG 3.28Å; R189-D200 IonicContact NH2-OD1 3.65Å; R189-D200 PolarHBondContact NH2-OD1 2.9Å; R189-D200 IonicContact NH2-OD2 3.68Å; R189-D200 PolarHBondContact NH2-OD2 3.34Å; R189-D200 VanDerWaalsContact NH2-OD2 3.16Å; M198-D200 VanDerWaalsContact C-N 3.25Å; M198-D200 PolarHBondContact O-N 2.81Å; D200-Q204 WeakPolarHBondContact O-CG 3.11Å
201I95.3Very high95.6Very high35 Ų3548.5 Ų48.518%0.17928%0.282CS..THydrogen-bonded Turntrans-98.7-36.8-179.3-63-61.6000111.4F173 G197 M198 T199 G203 Q204 M205 L241F173-I201 HydrophobicContact CD1-CG2 3.59Å; F173-I201 HydrophobicContact CE1-CG2 3.43Å; F173-I201 VanDerWaalsContact CE1-CG2 3.43Å; F173-I201 HydrophobicContact CG-CG2 4.35Å; F173-I201 HydrophobicContact CZ-CG2 4.06Å; G197-I201 WeakPolarHBondContact O-CG1 3.21Å; M198-I201 WeakPolarHBondContact O-CB 3.26Å; M198-I201 PolarHBondContact O-N 3.23Å; M198-I201 HydrophobicContact SD-CB 4.44Å; M198-I201 HydrophobicContact SD-CG2 4.39Å; T199-I201 VanDerWaalsContact C-N 3.33Å; I201-G203 PolarHBondContact O-N 3.47Å; I201-Q204 WeakPolarHBondContact O-CB 3.41Å; I201-Q204 PolarHBondContact O-N 3.29Å; I201-Q204 VanDerWaalsContact O-N 3.17Å; I201-M205 HydrophobicContact CG2-CE 3.49Å; I201-M205 VanDerWaalsContact CG2-CE 3.49Å; I201-M205 VanDerWaalsContact O-CE 3.31Å; I201-M205 WeakPolarHBondContact O-CE 3.37Å; I201-L241 HydrophobicContact CD1-CD1 4.44Å
202I96.4Very high95.5Very high0 Ų048.5 Ų48.50%028%0.282CS..THydrogen-bonded Turntrans-56.9137179.556.9166.8000111.5Y172 Y178 I191 M198 T199 Q204Y172-I202 HydrophobicContact CD1-CG2 3.76Å; Y172-I202 HydrophobicContact CG-CG2 4.36Å; Y178-I202 CarbonylContact O-C 3.38Å; I191-I202 HydrophobicContact CB-CD1 3.93Å; I191-I202 HydrophobicContact CG2-CD1 3.65Å; M198-I202 PolarHBondContact O-N 2.93Å; M198-I202 VanDerWaalsContact O-N 3.09Å; T199-I202 VanDerWaalsContact O-CG1 3.31Å; T199-I202 WeakPolarHBondContact O-CG1 3.49Å; I202-Q204 PolarHBondContact O-N 2.72Å
203G93.3Very high95.3Very high29 Ų2945.9 Ų45.930%0.29927%0.27SS..THydrogen-bonded Turntrans69.39.8-178.500000116.1H177 Y178 I201H177-G203 WeakPolarHBondContact O-CA 3.48Å; H177-G203 PolarHBondContact O-N 2.93Å; Y178-G203 PolarHBondContact O-N 2.88Å; I201-G203 PolarHBondContact O-N 3.47Å
204Q92.9Very high95.1Very high92 Ų9248.9 Ų48.943%0.4328%0.279SS..  trans-101.6-1.7179.1-58-54-54.100114.2D200 I201 I202D200-Q204 WeakPolarHBondContact O-CG 3.11Å; I201-Q204 WeakPolarHBondContact O-CB 3.41Å; I201-Q204 PolarHBondContact O-N 3.29Å; I201-Q204 VanDerWaalsContact O-N 3.17Å; I202-Q204 PolarHBondContact O-N 2.72Å
205M94Very high94.9Very high21 Ų2145 Ų4510%0.10326%0.256CS..  trans-68.2141.3-175.2-76.8-28.8105.300113F173 I201F173-M205 VanDerWaalsContact C-CG 3.49Å; F173-M205 HydrophobicContact CB-CE 4.31Å; F173-M205 HydrophobicContact CB-CG 4.15Å; F173-M205 HydrophobicContact CB-SD 4.06Å; F173-M205 HydrophobicContact CD1-CE 3.64Å; F173-M205 HydrophobicContact CD1-SD 3.89Å; F173-M205 HydrophobicContact CE1-CE 4.47Å; F173-M205 HydrophobicContact CG-CE 4.38Å; F173-M205 HydrophobicContact CG-SD 4.49Å; F173-M205 WeakPolarHBondContact O-CG 3.44Å; I201-M205 HydrophobicContact CG2-CE 3.49Å; I201-M205 VanDerWaalsContact CG2-CE 3.49Å; I201-M205 VanDerWaalsContact O-CE 3.31Å; I201-M205 WeakPolarHBondContact O-CE 3.37Å
206K93Very high94.8Very high129 Ų12940.4 Ų40.456%0.56123%0.234SC*.SBendtrans-110.4-0.4-177.7-59.6-53.7-176.3-1700114.3Y114 D115Y114-K206 WeakPolarHBondContact CD1-O 3.4Å; Y114-K206 WeakPolarHBondContact CE1-O 3.17Å; D115-K206 HydrophobicContact CB-CD 4.29Å; D115-K206 WeakPolarHBondContact OD2-CD 3.32Å; D115-K206 IonicContact OD2-NZ 4Å; D115-K206 PolarHBondContact OD2-NZ 2.91Å
207D95.7Very high94.7Very high34 Ų3434.8 Ų34.818%0.18220%0.197CC..SBendtrans-157.6174176.4-154.9-9.5000108.3R69 Y114 S209R69-D207 IonicContact CZ-OD1 2.81Å; R69-D207 IonicContact CZ-OD2 2.85Å; R69-D207 VanDerWaalsContact CZ-OD2 3.29Å; R69-D207 IonicContact NH1-OD1 2.66Å; R69-D207 PolarHBondContact NH1-OD1 3.2Å; R69-D207 IonicContact NH1-OD2 3.61Å; R69-D207 PolarHBondContact NH1-OD2 2.74Å; R69-D207 IonicContact NH2-OD2 3.17Å; R69-D207 PolarHBondContact NH2-OD2 2.89Å; Y114-D207 HydrophobicContact CE1-CB 4.17Å; Y114-D207 VanDerWaalsContact OH-CG 3.26Å; Y114-D207 PolarHBondContact OH-OD1 3.31Å; Y114-D207 PolarHBondContact OH-OD2 3.11Å; D207-S209 PolarHBondContact O-N 2.46Å
208F95.8Very high94.5Very high20 Ų2035.7 Ų35.79%0.08819%0.186CC..  trans-56.8141.4175.1-56.5-81.3000111.9A65 Y66 I118 M122 I175 D212 L213 I216A65-F208 HydrophobicContact CB-CE2 4.18Å; Y66-F208 HydrophobicContact CD1-CE1 4.31Å; Y66-F208 AromaticContact CD1-CZ 3.78Å; Y66-F208 HydrophobicContact CD1-CZ 3.78Å; Y66-F208 AromaticContact CD2-CZ 3.77Å; Y66-F208 HydrophobicContact CD2-CZ 3.77Å; Y66-F208 AromaticContact CE1-CE1 3.63Å; Y66-F208 HydrophobicContact CE1-CE1 3.63Å; Y66-F208 AromaticContact CE1-CZ 3.48Å; Y66-F208 HydrophobicContact CE1-CZ 3.48Å; Y66-F208 VanDerWaalsContact CE1-CZ 3.48Å; Y66-F208 HydrophobicContact CE2-CE1 4.15Å; Y66-F208 HydrophobicContact CE2-CE2 4.5Å; Y66-F208 AromaticContact CE2-CZ 3.49Å; Y66-F208 HydrophobicContact CE2-CZ 3.49Å; Y66-F208 VanDerWaalsContact CE2-CZ 3.49Å; Y66-F208 AromaticContact CG-CZ 3.9Å; Y66-F208 HydrophobicContact CG-CZ 3.9Å; Y66-F208 AromaticContact CZ-CE1 3.53Å; Y66-F208 AromaticContact CZ-CZ 3.32Å; Y66-F208 WeakPolarHBondContact OH-CE1 3.18Å; I118-F208 HydrophobicContact CD1-CD2 4.22Å; I118-F208 HydrophobicContact CD1-CE2 3.43Å; I118-F208 VanDerWaalsContact CD1-CE2 3.43Å; I118-F208 HydrophobicContact CD1-CZ 3.67Å; I118-F208 HydrophobicContact CG2-CD1 3.85Å; I118-F208 HydrophobicContact CG2-CD2 4.29Å; I118-F208 HydrophobicContact CG2-CE1 3.38Å; I118-F208 HydrophobicContact CG2-CE2 3.9Å; I118-F208 HydrophobicContact CG2-CG 4.29Å; I118-F208 HydrophobicContact CG2-CZ 3.42Å; I118-F208 VanDerWaalsContact CG2-CZ 3.42Å; M122-F208 HydrophobicContact SD-CD1 4.2Å; M122-F208 HydrophobicContact SD-CE1 4.24Å; I175-F208 HydrophobicContact CG2-CD1 4.43Å; F208-D212 HydrophobicContact CB-CB 4.13Å; F208-D212 HydrophobicContact CD1-CB 4.18Å; F208-L213 HydrophobicContact CB-CD1 4.28Å; F208-L213 HydrophobicContact CB-CD2 3.86Å; F208-L213 HydrophobicContact CB-CG 3.74Å; F208-L213 HydrophobicContact CD1-CD2 4.21Å; F208-L213 HydrophobicContact CD2-CD2 3.84Å; F208-L213 HydrophobicContact CE2-CD2 4.36Å; F208-L213 HydrophobicContact CG-CD2 3.72Å; F208-L213 HydrophobicContact CG-CG 4.18Å; F208-I216 HydrophobicContact CD1-CD1 4.14Å; F208-I216 HydrophobicContact CE1-CD1 3.88Å
209S95.4Very high94.3Very high12 Ų1234.4 Ų34.48%0.08418%0.179CC..  trans-72.2163.3161.7101.50000111.2D171 F173 D207 V211 D212 L213D171-S209 WeakPolarHBondContact OD2-CB 3.35Å; D171-S209 PolarHBondContact OD2-OG 3.26Å; F173-S209 WeakPolarHBondContact O-CB 3.31Å; D207-S209 PolarHBondContact O-N 2.46Å; S209-V211 PolarHBondContact O-N 3.4Å; S209-V211 WeakPolarHBondContact OG-CA 3.42Å; S209-V211 WeakPolarHBondContact OG-CB 3.41Å; S209-V211 PolarHBondContact OG-N 3.3Å; S209-D212 WeakPolarHBondContact CB-OD2 3.49Å; S209-D212 PolarHBondContact N-OD2 3.2Å; S209-D212 PolarHBondContact O-N 2.75Å; S209-D212 PolarHBondContact OG-N 3.49Å; S209-D212 PolarHBondContact OG-OD2 2.9Å; S209-L213 PolarHBondContact O-N 2.95Å
210A93.4Very high94.1Very high48 Ų4834.1 Ų34.140%0.39718%0.177SC..Hα-helixtrans-60.7-31.5169.600000112.2R214 I230A210-R214 WeakPolarHBondContact O-CG 3.15Å; A210-R214 PolarHBondContact O-N 3.1Å; A210-R214 VanDerWaalsContact O-N 3.16Å; A210-R214 PolarHBondContact O-NH1 3.15Å; A210-I230 HydrophobicContact CB-CG2 3.62Å; A210-I230 WeakPolarHBondContact O-CG2 3.26Å
211V93.2Very high94Very high16 Ų1636 Ų3610%0.09719%0.187CC..Hα-helixtrans-73.1-41.7177.8-178.40000110.3E168 D171 S209 L213 R214 K215E168-V211 HydrophobicContact CB-CG1 3.74Å; E168-V211 HydrophobicContact CG-CG1 4.13Å; D171-V211 HydrophobicContact CB-CB 3.91Å; D171-V211 HydrophobicContact CB-CG1 3.98Å; D171-V211 HydrophobicContact CB-CG2 3.97Å; D171-V211 WeakPolarHBondContact OD2-CB 3.42Å; S209-V211 PolarHBondContact O-N 3.4Å; S209-V211 WeakPolarHBondContact OG-CA 3.42Å; S209-V211 WeakPolarHBondContact OG-CB 3.41Å; S209-V211 PolarHBondContact OG-N 3.3Å; V211-L213 VanDerWaalsContact C-N 3.32Å; V211-L213 PolarHBondContact O-N 3.48Å; V211-R214 PolarHBondContact O-N 2.77Å; V211-R214 VanDerWaalsContact O-N 3.17Å; V211-K215 HydrophobicContact CG1-CD 4.08Å; V211-K215 HydrophobicContact CG1-CG 4.22Å; V211-K215 WeakPolarHBondContact O-CB 3.42Å; V211-K215 WeakPolarHBondContact O-CG 3.07Å; V211-K215 PolarHBondContact O-N 2.86Å
212D95.9Very high93.9Very high0 Ų034.7 Ų34.70%018%0.18CC..Hα-helixtrans-54.7-50.7175.9-67-31.2000110.4M122 S174 I175 F208 S209 R214 K215 I216M122-D212 HydrophobicContact CE-CB 3.83Å; M122-D212 HydrophobicContact SD-CB 4.24Å; S174-D212 WeakPolarHBondContact CA-OD2 3.3Å; S174-D212 WeakPolarHBondContact CB-OD1 3.15Å; S174-D212 PolarHBondContact OG-OD1 3.13Å; I175-D212 PolarHBondContact N-OD2 3.35Å; F208-D212 HydrophobicContact CB-CB 4.13Å; F208-D212 HydrophobicContact CD1-CB 4.18Å; S209-D212 WeakPolarHBondContact CB-OD2 3.49Å; S209-D212 PolarHBondContact N-OD2 3.2Å; S209-D212 PolarHBondContact O-N 2.75Å; S209-D212 PolarHBondContact OG-N 3.49Å; S209-D212 PolarHBondContact OG-OD2 2.9Å; D212-R214 PolarHBondContact O-N 3.07Å; D212-K215 WeakPolarHBondContact O-CB 3.44Å; D212-K215 PolarHBondContact O-N 3.43Å; D212-I216 VanDerWaalsContact O-CG1 3.31Å; D212-I216 WeakPolarHBondContact O-CG1 3.42Å; D212-I216 PolarHBondContact O-N 3.14Å
213L95.4Very high93.8Very high16 Ų1638.1 Ų38.18%0.08420%0.203CC..Hα-helixtrans-63.1-39.8178.5-64.7174.9000112.3R69 T70 F208 S209 V211 I216 N217 I230R69-L213 HydrophobicContact CB-CD1 4.12Å; R69-L213 HydrophobicContact CB-CD2 3.74Å; T70-L213 HydrophobicContact CG2-CD2 3.9Å; F208-L213 HydrophobicContact CB-CD1 4.28Å; F208-L213 HydrophobicContact CB-CD2 3.86Å; F208-L213 HydrophobicContact CB-CG 3.74Å; F208-L213 HydrophobicContact CD1-CD2 4.21Å; F208-L213 HydrophobicContact CD2-CD2 3.84Å; F208-L213 HydrophobicContact CE2-CD2 4.36Å; F208-L213 HydrophobicContact CG-CD2 3.72Å; F208-L213 HydrophobicContact CG-CG 4.18Å; S209-L213 PolarHBondContact O-N 2.95Å; V211-L213 VanDerWaalsContact C-N 3.32Å; V211-L213 PolarHBondContact O-N 3.48Å; L213-I216 PolarHBondContact O-N 2.61Å; L213-N217 VanDerWaalsContact O-CB 3.23Å; L213-N217 WeakPolarHBondContact O-CB 3.44Å; L213-N217 PolarHBondContact O-N 3.05Å; L213-N217 PolarHBondContact O-ND2 3.48Å; L213-N217 VanDerWaalsContact O-ND2 3.07Å; L213-I230 HydrophobicContact CB-CD1 3.42Å; L213-I230 VanDerWaalsContact CB-CD1 3.42Å; L213-I230 HydrophobicContact CB-CG1 3.82Å; L213-I230 HydrophobicContact CD1-CG1 4.01Å
214R93.2Very high93.3Very high76 Ų7641.3 Ų41.329%0.28722%0.218SC..Hα-helixtrans-64.9-41.7175.3-75.4-167.7-53.3-84.92.2111.8E168 A210 V211 D212 N217 K218 I230E168-R214 VanDerWaalsContact CD-NE 3.28Å; E168-R214 HydrophobicContact CG-CB 4.41Å; E168-R214 IonicContact OE1-NE 3.99Å; E168-R214 PolarHBondContact OE1-NE 3.32Å; E168-R214 VanDerWaalsContact OE1-NE 3.17Å; E168-R214 IonicContact OE2-CZ 2.86Å; E168-R214 VanDerWaalsContact OE2-CZ 3.28Å; E168-R214 IonicContact OE2-NE 3.53Å; E168-R214 PolarHBondContact OE2-NE 2.94Å; E168-R214 IonicContact OE2-NH2 2.9Å; E168-R214 PolarHBondContact OE2-NH2 3.31Å; A210-R214 WeakPolarHBondContact O-CG 3.15Å; A210-R214 PolarHBondContact O-N 3.1Å; A210-R214 VanDerWaalsContact O-N 3.16Å; A210-R214 PolarHBondContact O-NH1 3.15Å; V211-R214 PolarHBondContact O-N 2.77Å; V211-R214 VanDerWaalsContact O-N 3.17Å; D212-R214 PolarHBondContact O-N 3.07Å; R214-N217 PolarHBondContact O-N 3.06Å; R214-K218 WeakPolarHBondContact O-CB 3.29Å; R214-K218 VanDerWaalsContact O-CG 3.27Å; R214-K218 WeakPolarHBondContact O-CG 3.41Å; R214-K218 PolarHBondContact O-N 3.38Å; R214-I230 HydrophobicContact CG-CD1 3.97Å; R214-I230 HydrophobicContact CG-CG2 4.23Å
215K93Very high93Very high0 Ų044 Ų440%023%0.226CC..Hα-helixtrans-60.6-49.7175.9-72.6174.51791570110.6N29 F127 E130 Y166 E168 V211 D212 N217 K218 M219N29-K215 WeakPolarHBondContact ND2-CE 3.31Å; N29-K215 PolarHBondContact ND2-NZ 3.18Å; F127-K215 HydrophobicContact CE1-CB 3.62Å; F127-K215 HydrophobicContact CE1-CD 4.33Å; F127-K215 HydrophobicContact CE1-CG 4.47Å; F127-K215 HydrophobicContact CZ-CB 3.83Å; E130-K215 IonicContact OE1-NZ 3.65Å; E130-K215 PolarHBondContact OE1-NZ 2.62Å; E130-K215 IonicContact OE2-NZ 2.61Å; E130-K215 PolarHBondContact OE2-NZ 2.52Å; Y166-K215 HydrophobicContact CD2-CB 4.43Å; E168-K215 HydrophobicContact CB-CG 4.06Å; E168-K215 HydrophobicContact CG-CG 3.85Å; V211-K215 HydrophobicContact CG1-CD 4.08Å; V211-K215 HydrophobicContact CG1-CG 4.22Å; V211-K215 WeakPolarHBondContact O-CB 3.42Å; V211-K215 WeakPolarHBondContact O-CG 3.07Å; V211-K215 PolarHBondContact O-N 2.86Å; D212-K215 WeakPolarHBondContact O-CB 3.44Å; D212-K215 PolarHBondContact O-N 3.43Å; K215-N217 PolarHBondContact O-N 3.21Å; K215-K218 PolarHBondContact O-N 3.23Å; K215-M219 VanDerWaalsContact O-CB 3.31Å; K215-M219 WeakPolarHBondContact O-CB 3.39Å; K215-M219 PolarHBondContact O-N 2.8Å
216I94.7Very high92.5Very high0 Ų044.4 Ų44.40%023%0.226CC..Hα-helixtrans-59.4-48.8177.6-63.3160.6000110.6Y66 T70 V72 M122 V125 F127 F208 D212 L213 K218 M219 Y220Y66-I216 HydrophobicContact CE1-CD1 4.11Å; T70-I216 HydrophobicContact CG2-CB 4.25Å; T70-I216 HydrophobicContact CG2-CD1 4.42Å; T70-I216 HydrophobicContact CG2-CG2 3.75Å; V72-I216 HydrophobicContact CG2-CG2 3.93Å; M122-I216 HydrophobicContact CE-CD1 4.18Å; M122-I216 HydrophobicContact CE-CG1 4.25Å; M122-I216 HydrophobicContact CG-CD1 4.4Å; M122-I216 HydrophobicContact SD-CD1 4.24Å; V125-I216 HydrophobicContact CG1-CG1 4.33Å; V125-I216 HydrophobicContact CG1-CG2 4.19Å; F127-I216 HydrophobicContact CD2-CG1 4.15Å; F127-I216 HydrophobicContact CE2-CB 4.25Å; F127-I216 HydrophobicContact CE2-CG1 3.47Å; F127-I216 VanDerWaalsContact CE2-CG1 3.47Å; F127-I216 HydrophobicContact CZ-CG1 4.03Å; F208-I216 HydrophobicContact CD1-CD1 4.14Å; F208-I216 HydrophobicContact CE1-CD1 3.88Å; D212-I216 VanDerWaalsContact O-CG1 3.31Å; D212-I216 WeakPolarHBondContact O-CG1 3.42Å; D212-I216 PolarHBondContact O-N 3.14Å; L213-I216 PolarHBondContact O-N 2.61Å; I216-K218 PolarHBondContact O-N 2.67Å; I216-M219 WeakPolarHBondContact O-CB 3.45Å; I216-M219 PolarHBondContact O-N 2.75Å; I216-M219 VanDerWaalsContact O-N 3.15Å; I216-Y220 HydrophobicContact CG2-CD2 4.21Å; I216-Y220 PolarHBondContact O-N 3.37Å
217N93.9Very high91.5Very high1 Ų142.8 Ų42.81%0.00522%0.221CC..Hα-helixtrans-67.2-35.1-176.1-73.6-33000113.1R69 T70 L213 R214 K215 N221 C222 I230R69-N217 PolarHBondContact O-ND2 3.16Å; R69-N217 VanDerWaalsContact O-ND2 3.16Å; T70-N217 WeakPolarHBondContact CA-OD1 3.38Å; T70-N217 VanDerWaalsContact CB-OD1 3.31Å; T70-N217 WeakPolarHBondContact CB-OD1 3.41Å; L213-N217 VanDerWaalsContact O-CB 3.23Å; L213-N217 WeakPolarHBondContact O-CB 3.44Å; L213-N217 PolarHBondContact O-N 3.05Å; L213-N217 PolarHBondContact O-ND2 3.48Å; L213-N217 VanDerWaalsContact O-ND2 3.07Å; R214-N217 PolarHBondContact O-N 3.06Å; K215-N217 PolarHBondContact O-N 3.21Å; N217-N221 WeakPolarHBondContact O-CA 3.43Å; N217-N221 PolarHBondContact O-N 3.24Å; N217-N221 VanDerWaalsContact O-N 3.13Å; N217-C222 HydrophobicContact CB-CB 3.95Å; N217-C222 PolarHBondContact O-N 3.39Å; N217-C222 WeakPolarHBondContact OD1-CB 3.09Å; N217-C222 PolarHBondContact OD1-SG 2.81Å; N217-I230 WeakPolarHBondContact ND2-CD1 3.4Å
218K91.4Very high89.9Confident74 Ų7449.3 Ų49.332%0.32224%0.244SC..Hα-helixtrans-69.6-39.6170.9-74.2176.3175.1176.30111.8Y166 E168 R214 K215 I216 Y220 N221Y166-K218 HydrophobicContact CD1-CB 3.95Å; Y166-K218 HydrophobicContact CG-CB 4.09Å; Y166-K218 WeakPolarHBondContact O-CD 3.44Å; Y166-K218 PolarHBondContact O-NZ 3.33Å; E168-K218 WeakPolarHBondContact OE1-CE 3.34Å; E168-K218 IonicContact OE1-NZ 3.64Å; E168-K218 PolarHBondContact OE1-NZ 2.91Å; R214-K218 WeakPolarHBondContact O-CB 3.29Å; R214-K218 VanDerWaalsContact O-CG 3.27Å; R214-K218 WeakPolarHBondContact O-CG 3.41Å; R214-K218 PolarHBondContact O-N 3.38Å; K215-K218 PolarHBondContact O-N 3.23Å; I216-K218 PolarHBondContact O-N 2.67Å; K218-Y220 PolarHBondContact O-N 2.87Å; K218-N221 PolarHBondContact O-N 2.83Å; K218-N221 PolarHBondContact O-OD1 3.17Å
219M91.3Very high88.5Confident1 Ų151 Ų511%0.00525%0.253CS..Hα-helixtrans-61-42.7179.5180158.587.100113V31 K37 V125 F127 Y166 K215 I216V31-M219 HydrophobicContact CG2-CE 4.19Å; V31-M219 HydrophobicContact CG2-SD 3.72Å; K37-M219 HydrophobicContact CD-CG 4.28Å; K37-M219 PolarHBondContact NZ-O 2.94Å; V125-M219 HydrophobicContact CG1-CE 3.91Å; V125-M219 WeakPolarHBondContact O-CE 3.46Å; F127-M219 HydrophobicContact CD2-CE 4.02Å; F127-M219 HydrophobicContact CE2-CE 3.31Å; F127-M219 HydrophobicContact CE2-SD 4.01Å; F127-M219 HydrophobicContact CZ-CB 4.26Å; F127-M219 HydrophobicContact CZ-CE 3.77Å; F127-M219 HydrophobicContact CZ-SD 3.85Å; Y166-M219 HydrophobicContact CD1-CB 4.49Å; Y166-M219 HydrophobicContact CD2-CB 4.48Å; Y166-M219 VanDerWaalsContact CE1-CA 3.49Å; Y166-M219 HydrophobicContact CE1-CB 3.84Å; Y166-M219 HydrophobicContact CE1-CG 4.26Å; Y166-M219 HydrophobicContact CE2-CB 3.8Å; Y166-M219 HydrophobicContact CE2-CG 4.16Å; Y166-M219 HydrophobicContact CE2-SD 3.99Å; Y166-M219 VanDerWaalsContact CZ-CB 3.45Å; Y166-M219 WeakPolarHBondContact OH-CG 3.5Å; Y166-M219 PolarHBondContact OH-SD 2.93Å; K215-M219 VanDerWaalsContact O-CB 3.31Å; K215-M219 WeakPolarHBondContact O-CB 3.39Å; K215-M219 PolarHBondContact O-N 2.8Å; I216-M219 WeakPolarHBondContact O-CB 3.45Å; I216-M219 PolarHBondContact O-N 2.75Å; I216-M219 VanDerWaalsContact O-N 3.15Å
220Y93.3Very high87.4Confident9 Ų951 Ų514%0.03525%0.252CS..THydrogen-bonded Turntrans-98.310.1-178-75.9-79000114K37 W38 N41 V72 V125 I216 K218 C222K37-Y220 HydrophobicContact CB-CE1 4.43Å; W38-Y220 HydrophobicContact CB-CE1 4.46Å; N41-Y220 HydrophobicContact CB-CD1 3.96Å; N41-Y220 PolarHBondContact ND2-O 2.96Å; N41-Y220 VanDerWaalsContact OD1-CD1 3.25Å; N41-Y220 WeakPolarHBondContact OD1-CD1 3.49Å; V72-Y220 HydrophobicContact CG2-CD1 4.43Å; V72-Y220 HydrophobicContact CG2-CD2 3.49Å; V72-Y220 VanDerWaalsContact CG2-CD2 3.49Å; V72-Y220 HydrophobicContact CG2-CE2 3.73Å; V72-Y220 HydrophobicContact CG2-CG 3.87Å; V125-Y220 HydrophobicContact CG1-CD2 4.44Å; V125-Y220 HydrophobicContact CG1-CE2 3.62Å; V125-Y220 PolarHBondContact O-OH 2.7Å; I216-Y220 HydrophobicContact CG2-CD2 4.21Å; I216-Y220 PolarHBondContact O-N 3.37Å; K218-Y220 PolarHBondContact O-N 2.87Å; Y220-C222 PolarHBondContact O-N 2.78Å
221N92.8Very high85.6Confident143 Ų14351.5 Ų51.577%0.76526%0.261SS*.THydrogen-bonded Turntrans49.145-178.5-62.1-40.7000112.8N217 K218N217-N221 WeakPolarHBondContact O-CA 3.43Å; N217-N221 PolarHBondContact O-N 3.24Å; N217-N221 VanDerWaalsContact O-N 3.13Å; K218-N221 PolarHBondContact O-N 2.83Å; K218-N221 PolarHBondContact O-OD1 3.17Å
222C94.7Very high83.6Confident7 Ų757 Ų575%0.04729%0.29CS..  trans-64148.4-178.4-60.20000111.6C71 N217 Y220 Y226C71-C222 HydrophobicContact CB-CB 3.59Å; C71-C222 WeakPolarHBondContact CB-SG 3.45Å; C71-C222 PolarHBondContact N-SG 2.66Å; C71-C222 WeakPolarHBondContact SG-CA 3.44Å; C71-C222 WeakPolarHBondContact SG-CB 3.06Å; C71-C222 CovalentContact SG-SG 2.02Å; C71-C222 PolarHBondContact SG-SG 3.38Å; N217-C222 HydrophobicContact CB-CB 3.95Å; N217-C222 PolarHBondContact O-N 3.39Å; N217-C222 WeakPolarHBondContact OD1-CB 3.09Å; N217-C222 PolarHBondContact OD1-SG 2.81Å; Y220-C222 PolarHBondContact O-N 2.78Å; C222-Y226 HydrophobicContact CB-CD2 4.01Å
223P92.9Very high81.4Confident73 Ų7360.4 Ų60.447%0.47431%0.311SS..  trans-54.6149.6178.4-27.734.8000113.2Y225 Y226P223-Y225 PolarHBondContact O-N 2.91Å; P223-Y226 PolarHBondContact O-N 3.47Å; P223-Y226 VanDerWaalsContact O-N 3.07Å
224P84.4Confident78.5Confident95 Ų9562.8 Ų62.862%0.61734%0.34SS*.Hα-helixtrans-54.8-26-176.7-28.435.2000115.5Y226 Q227 Y228P224-Y226 PolarHBondContact O-N 3.22Å; P224-Q227 WeakPolarHBondContact O-CB 3.31Å; P224-Q227 PolarHBondContact O-N 2.84Å; P224-Y228 PolarHBondContact O-N 3.43Å; P224-Y228 VanDerWaalsContact O-N 3.1Å
225Y86.1Confident75.9Confident150 Ų15061.1 Ų61.159%0.58835%0.346SS*.Hα-helixtrans-49-43174.1169.3-107.2000112.7P223 Q227 Y228 M229P223-Y225 PolarHBondContact O-N 2.91Å; Y225-Q227 VanDerWaalsContact C-N 3.33Å; Y225-Q227 PolarHBondContact O-N 2.9Å; Y225-Y228 PolarHBondContact O-N 3.48Å; Y225-M229 HydrophobicContact CD1-CE 3.85Å; Y225-M229 HydrophobicContact CE1-CE 3.29Å; Y225-M229 HydrophobicContact CE1-SD 3.73Å; Y225-M229 HydrophobicContact CE2-CG 4.2Å; Y225-M229 HydrophobicContact CE2-SD 4.05Å; Y225-M229 PolarHBondContact O-N 3.43Å; Y225-M229 PolarHBondContact OH-SD 3.41Å
226Y82.5Confident73.1Confident28 Ų2863.4 Ų63.411%0.1137%0.37CS..Hα-helixtrans-68.3-31.7179.2-71.1-69.9000113.1R69 T70 C71 R73 C222 P223 P224 M229 I230R69-Y226 WeakPolarHBondContact O-CD1 3.16Å; T70-Y226 VanDerWaalsContact O-CE1 3.24Å; T70-Y226 WeakPolarHBondContact O-CE1 3.25Å; T70-Y226 PolarHBondContact O-OH 3.44Å; C71-Y226 HydrophobicContact CB-CD2 4.41Å; C71-Y226 HydrophobicContact CB-CE2 4.04Å; R73-Y226 PolarHBondContact NH2-OH 3.32Å; C222-Y226 HydrophobicContact CB-CD2 4.01Å; P223-Y226 PolarHBondContact O-N 3.47Å; P223-Y226 VanDerWaalsContact O-N 3.07Å; P224-Y226 PolarHBondContact O-N 3.22Å; Y226-M229 HydrophobicContact CD1-CE 3.48Å; Y226-M229 VanDerWaalsContact CD1-CE 3.48Å; Y226-M229 HydrophobicContact CE1-CE 3.86Å; Y226-M229 HydrophobicContact CG-CE 4.39Å; Y226-I230 WeakPolarHBondContact O-CD1 3.23Å; Y226-I230 WeakPolarHBondContact O-CG1 3.38Å
227Q72.5Confident70.6Confident96 Ų9671.4 Ų71.445%0.44940%0.4SS..Hα-helixtrans-70.4-38.3176.4-59.7179.70.700111.2P224 Y225 I230 G231P224-Q227 WeakPolarHBondContact O-CB 3.31Å; P224-Q227 PolarHBondContact O-N 2.84Å; Y225-Q227 VanDerWaalsContact C-N 3.33Å; Y225-Q227 PolarHBondContact O-N 2.9Å; Q227-I230 PolarHBondContact O-N 3.45Å; Q227-G231 PolarHBondContact O-N 3.41Å
228Y62.5Low68Low170 Ų17075.3 Ų75.367%0.66742%0.421SS*.Hα-helixtrans-66.4-38.2179.8-126.1-83.9000112.7P224 Y225 I230 G231 N232P224-Y228 PolarHBondContact O-N 3.43Å; P224-Y228 VanDerWaalsContact O-N 3.1Å; Y225-Y228 PolarHBondContact O-N 3.48Å; Y228-I230 VanDerWaalsContact C-N 3.31Å; Y228-I230 PolarHBondContact O-N 2.81Å; Y228-G231 PolarHBondContact O-N 2.85Å; Y228-N232 PolarHBondContact O-N 3.17Å; Y228-N232 VanDerWaalsContact O-N 3.13Å
229M65.8Low65.3Low57 Ų5778.6 Ų78.628%0.28144%0.442SS..Hα-helixtrans-62.6-38.1177.2-70.4-164.2-67.700112.5D68 Y225 Y226 G231 T233D68-M229 WeakPolarHBondContact O-CE 2.91Å; Y225-M229 HydrophobicContact CD1-CE 3.85Å; Y225-M229 HydrophobicContact CE1-CE 3.29Å; Y225-M229 HydrophobicContact CE1-SD 3.73Å; Y225-M229 HydrophobicContact CE2-CG 4.2Å; Y225-M229 HydrophobicContact CE2-SD 4.05Å; Y225-M229 PolarHBondContact O-N 3.43Å; Y225-M229 PolarHBondContact OH-SD 3.41Å; Y226-M229 HydrophobicContact CD1-CE 3.48Å; Y226-M229 VanDerWaalsContact CD1-CE 3.48Å; Y226-M229 HydrophobicContact CE1-CE 3.86Å; Y226-M229 HydrophobicContact CG-CE 4.39Å; M229-G231 VanDerWaalsContact C-N 3.35Å; M229-T233 WeakPolarHBondContact O-CG2 3.36Å; M229-T233 PolarHBondContact O-N 3.17Å; M229-T233 PolarHBondContact O-OG1 2.86Å
230I72.3Confident62.7Low12 Ų1288.5 Ų88.56%0.06248%0.479CS..Hα-helixtrans-65.8-39.7178.5-60.6161.5000111.1A210 L213 R214 N217 Y226 Q227 Y228 T233A210-I230 HydrophobicContact CB-CG2 3.62Å; A210-I230 WeakPolarHBondContact O-CG2 3.26Å; L213-I230 HydrophobicContact CB-CD1 3.42Å; L213-I230 VanDerWaalsContact CB-CD1 3.42Å; L213-I230 HydrophobicContact CB-CG1 3.82Å; L213-I230 HydrophobicContact CD1-CG1 4.01Å; R214-I230 HydrophobicContact CG-CD1 3.97Å; R214-I230 HydrophobicContact CG-CG2 4.23Å; N217-I230 WeakPolarHBondContact ND2-CD1 3.4Å; Y226-I230 WeakPolarHBondContact O-CD1 3.23Å; Y226-I230 WeakPolarHBondContact O-CG1 3.38Å; Q227-I230 PolarHBondContact O-N 3.45Å; Y228-I230 VanDerWaalsContact C-N 3.31Å; Y228-I230 PolarHBondContact O-N 2.81Å; I230-T233 PolarHBondContact O-OG1 3.09Å
231G56.7Low59.9Low58 Ų5892 Ų9260%0.59850%0.498SS*.Hα-helixtrans-71.1-34.8-179.300000113.8Q227 Y228 M229Q227-G231 PolarHBondContact O-N 3.41Å; Y228-G231 PolarHBondContact O-N 2.85Å; M229-G231 VanDerWaalsContact C-N 3.35Å
232N49.8Very low57.1Low130 Ų13090.7 Ų90.770%0.69550%0.497SS*.Hα-helixtrans-83.2-14.4-178-87.5-11.7000114.3Y228 G234Y228-N232 PolarHBondContact O-N 3.17Å; Y228-N232 VanDerWaalsContact O-N 3.13Å; N232-G234 PolarHBondContact O-N 3.19Å
233T49.4Very low54.3Low72 Ų7296.4 Ų96.444%0.44253%0.532SS..THydrogen-bonded Turntrans-82.824.4174.150.50000114M229 I230 G235 G236M229-T233 WeakPolarHBondContact O-CG2 3.36Å; M229-T233 PolarHBondContact O-N 3.17Å; M229-T233 PolarHBondContact O-OG1 2.86Å; I230-T233 PolarHBondContact O-OG1 3.09Å; T233-G235 PolarHBondContact O-N 2.86Å; T233-G236 PolarHBondContact O-N 3.22Å
234G36.3Very low51.5Low67 Ų6799.7 Ų99.769%0.69155%0.55SS**THydrogen-bonded Turntrans-34.8106.2-177.500000113.5N232 G236N232-G234 PolarHBondContact O-N 3.19Å; G234-G236 PolarHBondContact O-N 3.16Å
235G38.4Very low49.2Very low40 Ų40100.9 Ų100.941%0.41256%0.556SS.*THydrogen-bonded Turntrans66.6-10.6170.700000118.5T233 W237 L238T233-G235 PolarHBondContact O-N 2.86Å; G235-W237 VanDerWaalsContact C-N 3.31Å; G235-W237 PolarHBondContact O-N 3.07Å; G235-L238 PolarHBondContact O-N 3.19Å
236G33.1Very low46.8Very low49 Ų4997.3 Ų97.351%0.50557%0.565SS.*THydrogen-bonded Turntrans-65.4-28.8-169.300000115.2T233 G234T233-G236 PolarHBondContact O-N 3.22Å; G234-G236 PolarHBondContact O-N 3.16Å
237W41.8Very low44.4Very low167 Ų167105.2 Ų105.263%0.63360%0.603SS**THydrogen-bonded Turntrans-87.4-21.5178.8-64.695.8000113.5G235 N239G235-W237 VanDerWaalsContact C-N 3.31Å; G235-W237 PolarHBondContact O-N 3.07Å; W237-N239 VanDerWaalsContact C-N 3.27Å; W237-N239 PolarHBondContact O-N 3.15Å
238L39.2Very low42.6Very low83 Ų83105.8 Ų105.844%0.43562%0.615SS.*G310 helixtrans-73.3-18.1176.3-74165.4000112.6F173 G235 R240F173-L238 HydrophobicContact CD1-CD2 3.75Å; F173-L238 HydrophobicContact CE1-CD2 4.15Å; F173-L238 HydrophobicContact CG-CD2 4.41Å; G235-L238 PolarHBondContact O-N 3.19Å; L238-R240 PolarHBondContact O-N 3.28Å; L238-R240 VanDerWaalsContact O-N 3.13Å
239N35.9Very low41.5Very low143 Ų143104.1 Ų104.177%0.76562%0.623SS**G310 helixtrans-80.617.3-179-71.6-13.9000114.5W237W237-N239 VanDerWaalsContact C-N 3.27Å; W237-N239 PolarHBondContact O-N 3.15Å
240R36.6Very low40Very low209 Ų209107.6 Ų107.679%0.78965%0.647SS**G310 helixtrans-116.625.9175.8-123.7-173.9-77.8-126.53.4113.4L238L238-R240 PolarHBondContact O-N 3.28Å; L238-R240 VanDerWaalsContact O-N 3.13Å
241L35.2Very low38Very low84 Ų84111.5 Ų111.544%0.4468%0.675SS.*SBendtrans-67.7134165.1-70.3168.1000109.4I201 T243I201-L241 HydrophobicContact CD1-CD1 4.44Å; L241-T243 PolarHBondContact O-N 3.38Å; L241-T243 VanDerWaalsContact O-N 3.14Å
242P32.6Very low37.1Very low114 Ų114114.9 Ų114.974%0.7468%0.684SS**  trans-67115.3174.7-4.618.9000108.5V244P242-V244 PolarHBondContact O-N 2.9Å
243T37Very low36.2Very low128 Ų128116.5 Ų116.579%0.78569%0.692SS**  trans-62.4104.7164.637.20000108.5L241 T245L241-T243 PolarHBondContact O-N 3.38Å; L241-T243 VanDerWaalsContact O-N 3.14Å; T243-T245 VanDerWaalsContact C-N 3.28Å; T243-T245 PolarHBondContact O-N 3.09Å; T243-T245 VanDerWaalsContact O-N 3.07Å
244V32.7Very low35.6Very low141 Ų141124.8 Ų124.886%0.85572%0.715SS**  trans-74.186.7163.61800000107.3P242P242-V244 PolarHBondContact O-N 2.9Å
245T36.1Very low35.4Very low120 Ų120127.3 Ų127.374%0.73672%0.722SS**  trans-146.4124.3160.550.70000108.7T243T243-T245 VanDerWaalsContact C-N 3.28Å; T243-T245 PolarHBondContact O-N 3.09Å; T243-T245 VanDerWaalsContact O-N 3.07Å
246G36Very low35.3Very low76 Ų76128.7 Ų128.778%0.78474%0.737SS**  trans-61.2144.9-176.200000114.5
247E33.5Very low35.4Very low194 Ų194131.8 Ų131.891%0.90775%0.748SS**  trans39.5150.9147.1-77.6-162.5159.600123.7
248P34.7Very low35.1Very low108 Ų108130.5 Ų130.570%0.70175%0.754SS**  trans-111.6146.2-138.838.3-28.5000113.4
249T37.5Very low34.9Very low134 Ų134133.2 Ų133.282%0.82277%0.767SS**  trans-157.8117.3149.941.10000113.5
250V34.8Very low34.5Very low130 Ų130134.4 Ų134.479%0.78877%0.773SS**  trans72.2123.7131.7-171.30000121
251S31.5Very low34.4Very low94 Ų94130 Ų13066%0.65777%0.771SS**  trans-20.2149.9162.262.30000118.2
252T38Very low34.2Very low129 Ų129131.6 Ų131.679%0.79179%0.789SS**  -165.9150.961.232.30000113.2
253L30.3Very low34.2Very low164 Ų164130.4 Ų130.486%0.85979%0.789SS**  trans-49145.3171.9-7391.9000115.1
254R36Very low34.1Very low246 Ų246129.4 Ų129.493%0.92879%0.785SS**  -168.6141.6112.3-103.2170.8-165.9-135.23.3113.5
255S32.2Very low34Very low120 Ų120130.6 Ų130.684%0.83979%0.785SS**  trans-65.5147.3-177.846.80000115.8
256G36.9Very low34.1Very low69 Ų69133.8 Ų133.871%0.71179%0.789SS**  trans-178.8126.5158.700000110.8
257P34.4Very low33.9Very low114 Ų114135.4 Ų135.474%0.7479%0.786SS**  trans-78.1150.8-174.534.7-32.4000109.2
258N36.5Very low34.1Very low141 Ų141132.1 Ų132.175%0.75478%0.781SS**  trans176.1126.1139.9-91.1-24.5000114.6
259I34Very low34.2Very low140 Ų140138.9 Ų138.972%0.71879%0.793SS**  trans75.399.8131.9-53.2163.9000117
260L28.4Very low33.9Very low168 Ų168135.7 Ų135.788%0.8879%0.786SS**PPolyproline II helixtrans-58.6133.4155.4-83.6141.9000110.8
261P33.7Very low34Very low117 Ų117137 Ų13776%0.7679%0.789SS**PPolyproline II helixtrans-101.4133.1154.617.70.3000111
262S32.6Very low34Very low116 Ų116139.3 Ų139.381%0.81179%0.794SS**PPolyproline II helixtrans-48.9138.6175.3-28.30000113.7
263A32.3Very low33.9Very low90 Ų90141.2 Ų141.274%0.74480%0.798SS**PPolyproline II helixtrans-65.2136.3164.400000110.3L265A263-L265 PolarHBondContact O-N 2.94Å
264P35.1Very low34.1Very low107 Ų107142.3 Ų142.370%0.69580%0.799SS**PPolyproline II helixtrans-77.9123.4176.427-25.5000110.8F266P264-F266 HydrophobicContact CB-CD2 4.44Å; P264-F266 HydrophobicContact CB-CE2 4.13Å; P264-F266 HydrophobicContact CG-CE2 4.41Å
265L30.3Very low34.2Very low165 Ų165134.9 Ų134.986%0.86479%0.79SS**PPolyproline II helixtrans-64.1127.5158.8-80.7141.9000109.4A263A263-L265 PolarHBondContact O-N 2.94Å
266F37.7Very low34.8Very low188 Ų188135 Ų13583%0.82579%0.786SS**  trans-122.4113.2159.7-80.8-78.9000109.5P264P264-F266 HydrophobicContact CB-CD2 4.44Å; P264-F266 HydrophobicContact CB-CE2 4.13Å; P264-F266 HydrophobicContact CG-CE2 4.41Å
267P32Very low35.9Very low110 Ų110136.8 Ų136.871%0.71479%0.787SS**  trans-91.1169.4161.835.6-27.8000111.1
268P38.1Very low37.5Very low124 Ų124137.4 Ų137.481%0.80578%0.783SS**  trans-96.3150.1-145.336.7-34000114.5
269R36.3Very low39.8Very low251 Ų251132.9 Ų132.995%0.94776%0.762SS**  trans-149.7127.2158.3-74.9-173.7-178.1-176.8-1106.2
270G31.5Very low42.3Very low66 Ų66131.4 Ų131.468%0.6875%0.752SS**  cis88.487.344.600000107.9
271N36.2Very low44.9Very low158 Ų158125.8 Ų125.885%0.84572%0.723SS**  trans178.2122.3140.1-91.8-1.7000110.8
272D30.9Very low47.2Very low143 Ų143126.1 Ų126.177%0.76571%0.712SS**  trans0.3119.1152.1-66.1-46.9000117.7
273L37.3Very low49.1Very low168 Ų168121.6 Ų121.688%0.8868%0.682SS**  trans-144.1119.8132.3-97.2143.7000106.1A275L273-A275 PolarHBondContact O-N 3.27Å
274H34.1Very low51.1Low187 Ų187123.3 Ų123.387%0.86668%0.683SS**  trans-52.782.9167.2-87.4-94.7000110.1V276H274-V276 VanDerWaalsContact C-N 3.33Å; H274-V276 PolarHBondContact O-N 2.87Å; H274-V276 VanDerWaalsContact O-N 3.1Å
275A38.5Very low53Low91 Ų91123.1 Ų123.175%0.75267%0.673SS**  trans-75.596.9161.100000105.4L273 S277L273-A275 PolarHBondContact O-N 3.27Å; A275-S277 PolarHBondContact O-N 3.08Å
276V44.2Very low55.1Low123 Ų123115.4 Ų115.475%0.74563%0.633SS**  trans-41.6114.7161.21760000105.9H274 I278H274-V276 VanDerWaalsContact C-N 3.33Å; H274-V276 PolarHBondContact O-N 2.87Å; H274-V276 VanDerWaalsContact O-N 3.1Å; V276-I278 VanDerWaalsContact C-N 3.26Å; V276-I278 PolarHBondContact O-N 3.17Å
277S59.9Low57.1Low106 Ų106114.7 Ų114.774%0.74163%0.625SS**  trans-63.497.7177.359.40000106.3A275 C279A275-S277 PolarHBondContact O-N 3.08Å; S277-C279 PolarHBondContact O-N 3.42Å
278I69Low58.9Low127 Ų127111.3 Ų111.365%0.65160%0.601SS**  trans-58.3113.2178.5-66.9172.7000105.8V276 E280V276-I278 VanDerWaalsContact C-N 3.26Å; V276-I278 PolarHBondContact O-N 3.17Å; I278-E280 HydrophobicContact CG2-CB 4.2Å; I278-E280 HydrophobicContact CG2-CG 3.55Å; I278-E280 WeakPolarHBondContact CG2-OE1 3.31Å; I278-E280 PolarHBondContact O-N 3.42Å
279C84.5Confident60.3Low46 Ų46106.8 Ų106.831%0.31157%0.569SS.*  trans-83.490.8-176.4-169.40000108.5S277 C313S277-C279 PolarHBondContact O-N 3.42Å; C279-C313 HydrophobicContact CB-CB 3.5Å; C279-C313 VanDerWaalsContact CB-CB 3.5Å; C279-C313 WeakPolarHBondContact CB-SG 3.49Å; C279-C313 PolarHBondContact O-SG 3.23Å; C279-C313 WeakPolarHBondContact SG-CA 3.36Å; C279-C313 WeakPolarHBondContact SG-CB 3.5Å; C279-C313 CovalentContact SG-SG 2Å; C279-C313 PolarHBondContact SG-SG 3.31Å
280E86.6Confident62.5Low108 Ų10899.2 Ų99.251%0.50555%0.547SS..  trans-127.4153.4-177.1-84.2178.3-178.400111.8I278 K282 P307 K308I278-E280 HydrophobicContact CG2-CB 4.2Å; I278-E280 HydrophobicContact CG2-CG 3.55Å; I278-E280 WeakPolarHBondContact CG2-OE1 3.31Å; I278-E280 PolarHBondContact O-N 3.42Å; E280-K282 PolarHBondContact O-N 3.44Å; E280-P307 WeakPolarHBondContact O-CD 3.37Å; E280-P307 VanDerWaalsContact O-CG 3.22Å; E280-P307 WeakPolarHBondContact O-CG 3.45Å; E280-K308 HydrophobicContact CG-CD 4.24Å
281D83.4Confident65Low51 Ų51101.5 Ų101.527%0.27354%0.543SS..  trans-71.1123.9173.9-66.4-29.6000110L305 C306 K308 S309D281-L305 CarbonylContact C-O 3.48Å; D281-L305 WeakPolarHBondContact CA-O 3.42Å; D281-C306 WeakPolarHBondContact OD1-CA 3.03Å; D281-K308 WeakPolarHBondContact OD1-CA 3.5Å; D281-K308 WeakPolarHBondContact OD1-CB 3.31Å; D281-K308 PolarHBondContact OD1-N 2.86Å; D281-S309 VanDerWaalsContact CG-N 3.33Å; D281-S309 PolarHBondContact OD1-N 3.13Å; D281-S309 WeakPolarHBondContact OD2-CB 3.21Å; D281-S309 PolarHBondContact OD2-N 3.3Å; D281-S309 PolarHBondContact OD2-OG 3.35Å
282K80.3Confident67.1Low123 Ų12399.1 Ų99.154%0.53552%0.522SS..SBendtrans-84.8-19.7174.6-55.5-171.9-178.2-174.40112.7E280 Y304 L305E280-K282 PolarHBondContact O-N 3.44Å; K282-Y304 HydrophobicContact CD-CE1 4.22Å; K282-Y304 WeakPolarHBondContact CD-O 3.43Å; K282-Y304 VanDerWaalsContact NZ-CE2 3.34Å; K282-L305 PolarHBondContact N-O 2.9Å
283A74.2Confident69.7Low22 Ų2292.8 Ų92.818%0.18249%0.489CS..SBendtrans-99.7132.1174.700000110.8Q285 C286 L305A283-Q285 PolarHBondContact O-N 3.18Å; A283-C286 PolarHBondContact O-SG 3.25Å; A283-L305 HydrophobicContact CB-CB 4.23Å; A283-L305 PolarHBondContact N-O 3.25Å; A283-L305 VanDerWaalsContact N-O 3.07Å
284T72.8Confident72Confident125 Ų12595.5 Ų95.577%0.76749%0.488SS*.THydrogen-bonded Turntrans-71.2-8.9-178.852.80000114.2
285Q74.6Confident74.2Confident103 Ų10387.8 Ų87.848%0.48146%0.455SS..THydrogen-bonded Turntrans-125.730.7-172.8-70-174.8-14.900113.2A283 W287 L288A283-Q285 PolarHBondContact O-N 3.18Å; Q285-W287 PolarHBondContact O-N 3.26Å; Q285-L288 HydrophobicContact CB-CD1 4.04Å; Q285-L288 HydrophobicContact CG-CD1 4.31Å; Q285-L288 WeakPolarHBondContact O-CB 3.42Å; Q285-L288 PolarHBondContact O-N 2.94Å
286C75.4Confident75.9Confident3 Ų391.8 Ų91.82%0.0246%0.463CS..G310 helixtrans-55.6-34-179.6-70.80000114A283 L288 I289 I290 C306 S309A283-C286 PolarHBondContact O-SG 3.25Å; C286-L288 PolarHBondContact O-N 2.92Å; C286-I289 CarbonylContact O-C 3.58Å; C286-I289 PolarHBondContact O-N 2.97Å; C286-I290 PolarHBondContact O-N 3.13Å; C286-C306 WeakPolarHBondContact CA-SG 3.5Å; C286-C306 HydrophobicContact CB-CB 3.66Å; C286-C306 WeakPolarHBondContact CB-SG 3.36Å; C286-C306 WeakPolarHBondContact SG-CA 3.44Å; C286-C306 WeakPolarHBondContact SG-CB 3.23Å; C286-C306 CovalentContact SG-SG 2.02Å; C286-C306 PolarHBondContact SG-SG 3.37Å; C286-S309 VanDerWaalsContact CB-CB 3.46Å; C286-S309 WeakPolarHBondContact CB-OG 3.14Å
287W80.5Confident76.9Confident174 Ų17495 Ų9566%0.65947%0.467SS*.G310 helixtrans-57.3-30.5176.365.4-91000113.5Q285 I289Q285-W287 PolarHBondContact O-N 3.26Å; W287-I289 VanDerWaalsContact C-N 3.32Å; W287-I289 PolarHBondContact O-N 2.97Å
288L68.5Low77.5Confident39 Ų3993.3 Ų93.320%0.20445%0.445CS..G310 helixtrans-66.3-36.1176.3-74.4174.8000111.2V23 R24 Q285 C286V23-L288 HydrophobicContact CG1-CD1 4.41Å; R24-L288 PolarHBondContact NH1-O 3.2Å; R24-L288 PolarHBondContact NH2-O 2.52Å; Q285-L288 HydrophobicContact CB-CD1 4.04Å; Q285-L288 HydrophobicContact CG-CD1 4.31Å; Q285-L288 WeakPolarHBondContact O-CB 3.42Å; Q285-L288 PolarHBondContact O-N 2.94Å; C286-L288 PolarHBondContact O-N 2.92Å
289I68.7Low78.1Confident28 Ų2890.5 Ų90.514%0.14443%0.429CS..G310 helixtrans-110.716.9-173.647.5171.4000113.7R24 C286 W287 N291 R292 M302R24-I289 HydrophobicContact CB-CG2 4.21Å; R24-I289 VanDerWaalsContact CD-CG2 3.42Å; R24-I289 HydrophobicContact CG-CG2 3.41Å; R24-I289 VanDerWaalsContact CG-CG2 3.41Å; C286-I289 CarbonylContact O-C 3.58Å; C286-I289 PolarHBondContact O-N 2.97Å; W287-I289 VanDerWaalsContact C-N 3.32Å; W287-I289 PolarHBondContact O-N 2.97Å; I289-N291 PolarHBondContact O-N 3.4Å; I289-N291 VanDerWaalsContact O-N 3.12Å; I289-R292 HydrophobicContact CB-CG 4.4Å; I289-R292 VanDerWaalsContact O-CB 3.31Å; I289-R292 WeakPolarHBondContact O-CB 3.38Å; I289-R292 PolarHBondContact O-N 3.24Å; I289-M302 HydrophobicContact CB-CE 4.25Å; I289-M302 HydrophobicContact CB-SD 4.41Å; I289-M302 HydrophobicContact CD1-CE 4.03Å; I289-M302 HydrophobicContact CD1-SD 3.69Å; I289-M302 HydrophobicContact CG1-CE 3.91Å; I289-M302 HydrophobicContact CG1-SD 4.17Å; I289-M302 VanDerWaalsContact O-CE 3.25Å; I289-M302 WeakPolarHBondContact O-CE 3.41Å
290I81.3Confident78Confident92 Ų9296.8 Ų96.847%0.47245%0.452SS..G310 helixtrans-59.2-28.7-177.8-158.9166.7000112.7C286 R292 C293C286-I290 PolarHBondContact O-N 3.13Å; I290-R292 PolarHBondContact O-N 3.35Å; I290-R292 VanDerWaalsContact O-N 3.16Å; I290-C293 PolarHBondContact O-N 3.04Å; I290-C293 PolarHBondContact O-SG 3.44Å
291N83.6Confident77.4Confident114 Ų11493.7 Ų93.761%0.6144%0.438SS*.G310 helixtrans-69-8.7174.268.3-24.1000114.2I289I289-N291 PolarHBondContact O-N 3.4Å; I289-N291 VanDerWaalsContact O-N 3.12Å
292R81.5Confident77.4Confident108 Ų10891.4 Ų91.441%0.40843%0.426SS..G310 helixtrans-96.1-4.2177.9-58.7-61.1-173170.9-1.4113.5I289 I290 R294 S295 Y298 M302I289-R292 HydrophobicContact CB-CG 4.4Å; I289-R292 VanDerWaalsContact O-CB 3.31Å; I289-R292 WeakPolarHBondContact O-CB 3.38Å; I289-R292 PolarHBondContact O-N 3.24Å; I290-R292 PolarHBondContact O-N 3.35Å; I290-R292 VanDerWaalsContact O-N 3.16Å; R292-R294 PolarHBondContact O-N 2.9Å; R292-R294 VanDerWaalsContact O-N 3.13Å; R292-S295 VanDerWaalsContact O-CB 3.28Å; R292-S295 WeakPolarHBondContact O-CB 3.5Å; R292-S295 PolarHBondContact O-N 3.15Å; R292-Y298 HydrophobicContact CB-CD2 4.38Å; R292-Y298 HydrophobicContact CG-CD2 4.34Å; R292-M302 HydrophobicContact CB-CG 4.3Å; R292-M302 HydrophobicContact CB-SD 4.18Å
293C84.6Confident77.8Confident11 Ų1191.5 Ų91.57%0.07442%0.423CS..THydrogen-bonded Turntrans-49-45.1-176.8-65.80000112I290 C310 F312I290-C293 PolarHBondContact O-N 3.04Å; I290-C293 PolarHBondContact O-SG 3.44Å; C293-C310 VanDerWaalsContact CA-SG 3.55Å; C293-C310 HydrophobicContact CB-CB 3.54Å; C293-C310 WeakPolarHBondContact CB-SG 3.39Å; C293-C310 WeakPolarHBondContact SG-CA 3.44Å; C293-C310 WeakPolarHBondContact SG-CB 3.46Å; C293-C310 CovalentContact SG-SG 2.02Å; C293-C310 PolarHBondContact SG-SG 2.84Å; C293-F312 HydrophobicContact CB-CE2 4.47Å; C293-F312 HydrophobicContact CB-CZ 4.32Å; C293-F312 VanDerWaalsContact O-CZ 3.26Å; C293-F312 WeakPolarHBondContact O-CZ 3.49Å
294R85Confident78.2Confident224 Ų22495 Ų9585%0.84543%0.432SS*.THydrogen-bonded Turntrans-103.623.5-180-56.7-169.9-179.6-146.50.2114.4R292R292-R294 PolarHBondContact O-N 2.9Å; R292-R294 VanDerWaalsContact O-N 3.13Å
295S80.5Confident78.6Confident26 Ų2689.3 Ų89.318%0.18240%0.397CS..  trans-77.8127.2177.3172.10000110.4R292 F297 Y298 E299R292-S295 VanDerWaalsContact O-CB 3.28Å; R292-S295 WeakPolarHBondContact O-CB 3.5Å; R292-S295 PolarHBondContact O-N 3.15Å; S295-F297 PolarHBondContact O-N 3.18Å; S295-Y298 PolarHBondContact O-N 3.39Å; S295-Y298 VanDerWaalsContact OG-CD2 3.32Å; S295-Y298 WeakPolarHBondContact OG-CD2 3.13Å; S295-E299 PolarHBondContact O-N 3.37Å
296L75.9Confident79.1Confident175 Ų17584.4 Ų84.492%0.91637%0.374SS*.THydrogen-bonded Turntrans-43.5-39.4175.9-101.8142000113.9
297F64.7Low79.9Confident189 Ų18985 Ų8583%0.82938%0.378SS*.THydrogen-bonded Turntrans-85.9-21.3-179.4-71.3-83.3000115.5S295S295-F297 PolarHBondContact O-N 3.18Å
298Y72.6Confident80.4Confident71 Ų7182.4 Ų82.428%0.27837%0.371SS..THydrogen-bonded Turntrans-119.4-11.1-168.7-60.6-66.8000113.8L161 R292 S295 F300 L301 M302L161-Y298 HydrophobicContact CD2-CE1 4.45Å; R292-Y298 HydrophobicContact CB-CD2 4.38Å; R292-Y298 HydrophobicContact CG-CD2 4.34Å; S295-Y298 PolarHBondContact O-N 3.39Å; S295-Y298 VanDerWaalsContact OG-CD2 3.32Å; S295-Y298 WeakPolarHBondContact OG-CD2 3.13Å; Y298-F300 VanDerWaalsContact C-N 3.29Å; Y298-F300 PolarHBondContact O-N 2.82Å; Y298-L301 CarbonylContact O-C 3.36Å; Y298-L301 WeakPolarHBondContact O-CA 3.4Å; Y298-L301 WeakPolarHBondContact O-CB 3.45Å; Y298-L301 PolarHBondContact O-N 2.02Å; Y298-M302 WeakPolarHBondContact O-CG 3.33Å; Y298-M302 PolarHBondContact O-N 2.87Å
299E82.1Confident81.4Confident68 Ų6882.5 Ų82.532%0.31838%0.375SS..Hα-helixtrans-53-45.1-175.2-177.6177158.700112.5S295 L301 M302 R303 F312S295-E299 PolarHBondContact O-N 3.37Å; E299-L301 VanDerWaalsContact C-N 3.29Å; E299-L301 PolarHBondContact O-N 3.1Å; E299-M302 PolarHBondContact O-N 2.9Å; E299-M302 VanDerWaalsContact O-N 3.14Å; E299-R303 HydrophobicContact CG-CG 4.35Å; E299-R303 WeakPolarHBondContact O-CB 3.25Å; E299-R303 WeakPolarHBondContact O-CG 3.27Å; E299-R303 PolarHBondContact O-N 3.17Å; E299-R303 IonicContact OE1-CZ 3.49Å; E299-R303 VanDerWaalsContact OE1-CZ 3.26Å; E299-R303 IonicContact OE1-NE 3.78Å; E299-R303 PolarHBondContact OE1-NE 2.75Å; E299-R303 IonicContact OE1-NH2 3.05Å; E299-R303 PolarHBondContact OE1-NH2 3.1Å; E299-F312 HydrophobicContact CG-CZ 3.99Å
300F81Confident82.5Confident178 Ų17882.1 Ų82.178%0.78137%0.374SS*.Hα-helixtrans-56.2-44.7175.9176.9-95.7000112.2Y298 R303 Y304Y298-F300 VanDerWaalsContact C-N 3.29Å; Y298-F300 PolarHBondContact O-N 2.82Å; F300-R303 PolarHBondContact O-N 3.25Å; F300-Y304 PolarHBondContact O-N 3.43Å
301L75.3Confident82.9Confident43 Ų4380.6 Ų80.623%0.22538%0.382CS..Hα-helixtrans-67-40.6178.3-175.766.1000111.3L160 Y298 E299 Y304 L305L160-L301 HydrophobicContact CD1-CD1 3.5Å; L160-L301 VanDerWaalsContact CD1-CD1 3.5Å; L160-L301 HydrophobicContact CD1-CD2 4.24Å; Y298-L301 CarbonylContact O-C 3.36Å; Y298-L301 WeakPolarHBondContact O-CA 3.4Å; Y298-L301 WeakPolarHBondContact O-CB 3.45Å; Y298-L301 PolarHBondContact O-N 2.02Å; E299-L301 VanDerWaalsContact C-N 3.29Å; E299-L301 PolarHBondContact O-N 3.1Å; L301-Y304 PolarHBondContact O-N 3.41Å; L301-L305 HydrophobicContact CD1-CD1 3.5Å; L301-L305 VanDerWaalsContact CD1-CD1 3.5Å; L301-L305 HydrophobicContact CD1-CG 3.88Å; L301-L305 HydrophobicContact CD2-CD1 4.17Å; L301-L305 HydrophobicContact CG-CD1 3.62Å; L301-L305 HydrophobicContact CG-CG 4.23Å; L301-L305 WeakPolarHBondContact O-CB 3.37Å; L301-L305 WeakPolarHBondContact O-CG 3.05Å; L301-L305 PolarHBondContact O-N 3.12Å
302M83.3Confident83.2Confident3 Ų377 Ų772%0.01536%0.361CS..Hα-helixtrans-68.8-35.5179.2-62.9-56.7-65.400112I289 R292 Y298 E299 Y304 C306 C310 F312I289-M302 HydrophobicContact CB-CE 4.25Å; I289-M302 HydrophobicContact CB-SD 4.41Å; I289-M302 HydrophobicContact CD1-CE 4.03Å; I289-M302 HydrophobicContact CD1-SD 3.69Å; I289-M302 HydrophobicContact CG1-CE 3.91Å; I289-M302 HydrophobicContact CG1-SD 4.17Å; I289-M302 VanDerWaalsContact O-CE 3.25Å; I289-M302 WeakPolarHBondContact O-CE 3.41Å; R292-M302 HydrophobicContact CB-CG 4.3Å; R292-M302 HydrophobicContact CB-SD 4.18Å; Y298-M302 WeakPolarHBondContact O-CG 3.33Å; Y298-M302 PolarHBondContact O-N 2.87Å; E299-M302 PolarHBondContact O-N 2.9Å; E299-M302 VanDerWaalsContact O-N 3.14Å; M302-Y304 VanDerWaalsContact C-N 3.27Å; M302-Y304 PolarHBondContact O-N 2.72Å; M302-C306 HydrophobicContact CE-CB 3.86Å; M302-C306 CarbonylContact O-C 3.33Å; M302-C306 WeakPolarHBondContact O-CA 3.28Å; M302-C306 PolarHBondContact O-N 3.46Å; M302-C310 WeakPolarHBondContact CE-SG 3.49Å; M302-F312 HydrophobicContact CB-CE2 3.85Å
303R87.4Confident83.5Confident126 Ų12674.1 Ų74.148%0.47536%0.357SS..Hα-helixtrans-63-32.7170.5-75176.6177.8-81.70.1112.7E299 F300 P307 F312E299-R303 HydrophobicContact CG-CG 4.35Å; E299-R303 WeakPolarHBondContact O-CB 3.25Å; E299-R303 WeakPolarHBondContact O-CG 3.27Å; E299-R303 PolarHBondContact O-N 3.17Å; E299-R303 IonicContact OE1-CZ 3.49Å; E299-R303 VanDerWaalsContact OE1-CZ 3.26Å; E299-R303 IonicContact OE1-NE 3.78Å; E299-R303 PolarHBondContact OE1-NE 2.75Å; E299-R303 IonicContact OE1-NH2 3.05Å; E299-R303 PolarHBondContact OE1-NH2 3.1Å; F300-R303 PolarHBondContact O-N 3.25Å; R303-P307 WeakPolarHBondContact O-CB 3.44Å; R303-F312 HydrophobicContact CB-CD2 4.09Å; R303-F312 HydrophobicContact CB-CE2 4.35Å; R303-F312 HydrophobicContact CG-CB 4.38Å; R303-F312 HydrophobicContact CG-CD1 4.09Å; R303-F312 HydrophobicContact CG-CD2 3.46Å; R303-F312 VanDerWaalsContact CG-CD2 3.46Å; R303-F312 HydrophobicContact CG-CE1 4.18Å; R303-F312 HydrophobicContact CG-CE2 3.55Å; R303-F312 HydrophobicContact CG-CG 3.73Å; R303-F312 HydrophobicContact CG-CZ 3.91Å
304Y82.5Confident82.9Confident96 Ų9682.7 Ų82.738%0.37642%0.417SS..Hα-helixtrans-83-43.8178.7-178-102.1000113W134 K282 F300 L301 M302W134-Y304 HydrophobicContact CH2-CE1 4.02Å; W134-Y304 WeakPolarHBondContact CH2-OH 3.3Å; W134-Y304 HydrophobicContact CZ3-CE1 4.26Å; K282-Y304 HydrophobicContact CD-CE1 4.22Å; K282-Y304 WeakPolarHBondContact CD-O 3.43Å; K282-Y304 VanDerWaalsContact NZ-CE2 3.34Å; F300-Y304 PolarHBondContact O-N 3.43Å; L301-Y304 PolarHBondContact O-N 3.41Å; M302-Y304 VanDerWaalsContact C-N 3.27Å; M302-Y304 PolarHBondContact O-N 2.72Å
305L81.7Confident82.8Confident4 Ų475.6 Ų75.62%0.02140%0.395CS..Hα-helixtrans-94.3-34.3-170.6-66.7-179.2000114.8V26 D281 K282 A283 L301V26-L305 HydrophobicContact CB-CD1 3.81Å; V26-L305 HydrophobicContact CB-CD2 4.39Å; V26-L305 HydrophobicContact CG1-CD1 4.46Å; V26-L305 HydrophobicContact CG1-CD2 4.23Å; V26-L305 HydrophobicContact CG2-CD1 3.15Å; V26-L305 HydrophobicContact CG2-CD2 3.63Å; V26-L305 HydrophobicContact CG2-CG 3.99Å; D281-L305 CarbonylContact C-O 3.48Å; D281-L305 WeakPolarHBondContact CA-O 3.42Å; K282-L305 PolarHBondContact N-O 2.9Å; A283-L305 HydrophobicContact CB-CB 4.23Å; A283-L305 PolarHBondContact N-O 3.25Å; A283-L305 VanDerWaalsContact N-O 3.07Å; L301-L305 HydrophobicContact CD1-CD1 3.5Å; L301-L305 VanDerWaalsContact CD1-CD1 3.5Å; L301-L305 HydrophobicContact CD1-CG 3.88Å; L301-L305 HydrophobicContact CD2-CD1 4.17Å; L301-L305 HydrophobicContact CG-CD1 3.62Å; L301-L305 HydrophobicContact CG-CG 4.23Å; L301-L305 WeakPolarHBondContact O-CB 3.37Å; L301-L305 WeakPolarHBondContact O-CG 3.05Å; L301-L305 PolarHBondContact O-N 3.12Å
306C85.5Confident82.9Confident0 Ų078.2 Ų78.20%041%0.407CS..  trans-131.441.8-171.3-64.30000111.8D281 C286 M302 K308 S309 C310D281-C306 WeakPolarHBondContact OD1-CA 3.03Å; C286-C306 WeakPolarHBondContact CA-SG 3.5Å; C286-C306 HydrophobicContact CB-CB 3.66Å; C286-C306 WeakPolarHBondContact CB-SG 3.36Å; C286-C306 WeakPolarHBondContact SG-CA 3.44Å; C286-C306 WeakPolarHBondContact SG-CB 3.23Å; C286-C306 CovalentContact SG-SG 2.02Å; C286-C306 PolarHBondContact SG-SG 3.37Å; M302-C306 HydrophobicContact CE-CB 3.86Å; M302-C306 CarbonylContact O-C 3.33Å; M302-C306 WeakPolarHBondContact O-CA 3.28Å; M302-C306 PolarHBondContact O-N 3.46Å; C306-K308 PolarHBondContact O-N 3.16Å; C306-S309 PolarHBondContact O-N 3.43Å; C306-C310 WeakPolarHBondContact O-CB 3.24Å; C306-C310 PolarHBondContact O-N 2.76Å; C306-C310 PolarHBondContact O-SG 3.43Å
307P91.8Very high83.3Confident15 Ų1572.8 Ų72.810%0.09738%0.378CS..THydrogen-bonded Turntrans-63.2-30.8-173.527.7-35.5000112.6E280 R303 G311 F312 C313E280-P307 WeakPolarHBondContact O-CD 3.37Å; E280-P307 VanDerWaalsContact O-CG 3.22Å; E280-P307 WeakPolarHBondContact O-CG 3.45Å; R303-P307 WeakPolarHBondContact O-CB 3.44Å; P307-G311 PolarHBondContact O-N 2.97Å; P307-F312 HydrophobicContact CB-CB 4.11Å; P307-F312 WeakPolarHBondContact O-CA 3.35Å; P307-F312 PolarHBondContact O-N 3.21Å; P307-C313 PolarHBondContact O-N 3.07Å; P307-C313 PolarHBondContact O-SG 3Å
308K91.8Very high84.4Confident121 Ų12166 Ų6653%0.52635%0.352SS..THydrogen-bonded Turntrans-75.9-51.4178.4-171.9176.9-178.8173.90111.2E280 D281 C306 C310 G311 C313E280-K308 HydrophobicContact CG-CD 4.24Å; D281-K308 WeakPolarHBondContact OD1-CA 3.5Å; D281-K308 WeakPolarHBondContact OD1-CB 3.31Å; D281-K308 PolarHBondContact OD1-N 2.86Å; C306-K308 PolarHBondContact O-N 3.16Å; K308-C310 PolarHBondContact O-N 3.38Å; K308-G311 PolarHBondContact O-N 3.43Å; K308-G311 VanDerWaalsContact O-N 3.12Å; K308-C313 WeakPolarHBondContact CA-SG 3.42Å; K308-C313 PolarHBondContact N-SG 3.1Å
309S88.8Confident85.2Confident41 Ų4165.7 Ų65.729%0.28736%0.356SS..THydrogen-bonded Turntrans-60.1-32.2176.4-80.30000113.1D281 C286 C306D281-S309 VanDerWaalsContact CG-N 3.33Å; D281-S309 PolarHBondContact OD1-N 3.13Å; D281-S309 WeakPolarHBondContact OD2-CB 3.21Å; D281-S309 PolarHBondContact OD2-N 3.3Å; D281-S309 PolarHBondContact OD2-OG 3.35Å; C286-S309 VanDerWaalsContact CB-CB 3.46Å; C286-S309 WeakPolarHBondContact CB-OG 3.14Å; C306-S309 PolarHBondContact O-N 3.43Å
310C90.9Very high85.4Confident19 Ų1965.5 Ų65.513%0.12836%0.359CS..THydrogen-bonded Turntrans-87.9-3179-73.10000115.1C293 M302 C306 K308 F312C293-C310 VanDerWaalsContact CA-SG 3.55Å; C293-C310 HydrophobicContact CB-CB 3.54Å; C293-C310 WeakPolarHBondContact CB-SG 3.39Å; C293-C310 WeakPolarHBondContact SG-CA 3.44Å; C293-C310 WeakPolarHBondContact SG-CB 3.46Å; C293-C310 CovalentContact SG-SG 2.02Å; C293-C310 PolarHBondContact SG-SG 2.84Å; M302-C310 WeakPolarHBondContact CE-SG 3.49Å; C306-C310 WeakPolarHBondContact O-CB 3.24Å; C306-C310 PolarHBondContact O-N 2.76Å; C306-C310 PolarHBondContact O-SG 3.43Å; K308-C310 PolarHBondContact O-N 3.38Å; C310-F312 VanDerWaalsContact C-N 3.29Å; C310-F312 HydrophobicContact CB-CD2 3.28Å; C310-F312 HydrophobicContact CB-CE2 3.26Å; C310-F312 HydrophobicContact CB-CG 4.03Å; C310-F312 HydrophobicContact CB-CZ 3.98Å; C310-F312 PolarHBondContact O-N 3.43Å
311G90.4Very high85.7Confident61 Ų6157.5 Ų57.563%0.62933%0.329SS*.THydrogen-bonded Turntrans65.631.7-175.200000113.2P307 K308 C313P307-G311 PolarHBondContact O-N 2.97Å; K308-G311 PolarHBondContact O-N 3.43Å; K308-G311 VanDerWaalsContact O-N 3.12Å; G311-C313 VanDerWaalsContact C-N 3.35Å
312F91Very high86.5Confident37 Ų3758.6 Ų58.616%0.16234%0.337CS..  trans-87-6.8171.8-61.9-47.3000113.5C293 E299 M302 R303 P307 C310 S314C293-F312 HydrophobicContact CB-CE2 4.47Å; C293-F312 HydrophobicContact CB-CZ 4.32Å; C293-F312 VanDerWaalsContact O-CZ 3.26Å; C293-F312 WeakPolarHBondContact O-CZ 3.49Å; E299-F312 HydrophobicContact CG-CZ 3.99Å; M302-F312 HydrophobicContact CB-CE2 3.85Å; R303-F312 HydrophobicContact CB-CD2 4.09Å; R303-F312 HydrophobicContact CB-CE2 4.35Å; R303-F312 HydrophobicContact CG-CB 4.38Å; R303-F312 HydrophobicContact CG-CD1 4.09Å; R303-F312 HydrophobicContact CG-CD2 3.46Å; R303-F312 VanDerWaalsContact CG-CD2 3.46Å; R303-F312 HydrophobicContact CG-CE1 4.18Å; R303-F312 HydrophobicContact CG-CE2 3.55Å; R303-F312 HydrophobicContact CG-CG 3.73Å; R303-F312 HydrophobicContact CG-CZ 3.91Å; P307-F312 HydrophobicContact CB-CB 4.11Å; P307-F312 WeakPolarHBondContact O-CA 3.35Å; P307-F312 PolarHBondContact O-N 3.21Å; C310-F312 VanDerWaalsContact C-N 3.29Å; C310-F312 HydrophobicContact CB-CD2 3.28Å; C310-F312 HydrophobicContact CB-CE2 3.26Å; C310-F312 HydrophobicContact CB-CG 4.03Å; C310-F312 HydrophobicContact CB-CZ 3.98Å; C310-F312 PolarHBondContact O-N 3.43Å; F312-S314 PolarHBondContact O-N 3.27Å
313C87.2Confident86.8Confident49 Ų4963.3 Ų63.333%0.33136%0.364SS..  trans-72.5104.2168.5-54.20000109.7C279 P307 K308 G311C279-C313 HydrophobicContact CB-CB 3.5Å; C279-C313 VanDerWaalsContact CB-CB 3.5Å; C279-C313 WeakPolarHBondContact CB-SG 3.49Å; C279-C313 PolarHBondContact O-SG 3.23Å; C279-C313 WeakPolarHBondContact SG-CA 3.36Å; C279-C313 WeakPolarHBondContact SG-CB 3.5Å; C279-C313 CovalentContact SG-SG 2Å; C279-C313 PolarHBondContact SG-SG 3.31Å; P307-C313 PolarHBondContact O-N 3.07Å; P307-C313 PolarHBondContact O-SG 3Å; K308-C313 WeakPolarHBondContact CA-SG 3.42Å; K308-C313 PolarHBondContact N-SG 3.1Å; G311-C313 VanDerWaalsContact C-N 3.35Å
314S72.1Confident86.7Confident190 Ų19057.5 Ų57.5100%1.32935%0.353SS*.  trans-91.90170.257.30000111.5F312F312-S314 PolarHBondContact O-N 3.27Å

Retrieved 314 of 314 residues in 313.2 ms (Link to these results)