A0A077Z7X2_TRITR Loading...

alpha-glucosidase

AlphaFold DB , UniProt , Accession A0A077Z7X2, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 605 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M35.3Very low35Very low247 Ų247123 Ų123100%1.21782%0.822SS**  094.60-72176-17100107.4S3M1-S3 PolarHBondContact O-N 3.39Å
2A35.4Very low37Very low101 Ų101117.5 Ų117.584%0.83580%0.802SS**  trans-84.3104.4168.100000105.8V4A2-V4 PolarHBondContact O-N 3.34Å; A2-V4 VanDerWaalsContact O-N 3.13Å
3S37.7Very low40.2Very low102 Ų102112.2 Ų112.271%0.71377%0.766SS**  trans-61.1115.1171.756.20000107.4M1 T5M1-S3 PolarHBondContact O-N 3.39Å; S3-T5 VanDerWaalsContact C-N 3.34Å; S3-T5 PolarHBondContact O-N 3.38Å
4V37.5Very low43.5Very low139 Ų139112.6 Ų112.684%0.84274%0.743SS**  trans-61.6102.7165.9177.60000105.8A2 S6A2-V4 PolarHBondContact O-N 3.34Å; A2-V4 VanDerWaalsContact O-N 3.13Å; V4-S6 PolarHBondContact O-N 2.87Å
5T33.6Very low46.7Very low117 Ų117110.7 Ų110.772%0.71872%0.72SS**  trans-61.5104.3167.539.90000106.3S3 T7S3-T5 VanDerWaalsContact C-N 3.34Å; S3-T5 PolarHBondContact O-N 3.38Å; T5-T7 PolarHBondContact O-N 2.98Å
6S36.8Very low49.7Very low102 Ų102104.2 Ų104.271%0.71368%0.676SS**  trans-53.1111.7167.460.80000106.5V4 G8V4-S6 PolarHBondContact O-N 2.87Å; S6-G8 PolarHBondContact O-N 3.41Å; S6-G8 VanDerWaalsContact O-N 3.13Å
7T32.1Very low52.3Low121 Ų12199.1 Ų99.174%0.74264%0.64SS**  trans-44.8122.4165.444.20000107.2T5 I9T5-T7 PolarHBondContact O-N 2.98Å; T7-I9 PolarHBondContact O-N 3.33Å
8G27.1Very low54.5Low80 Ų8096.3 Ų96.383%0.82562%0.617SS**  trans-50.998.9-174.200000111S6 S10S6-G8 PolarHBondContact O-N 3.41Å; S6-G8 VanDerWaalsContact O-N 3.13Å; G8-S10 PolarHBondContact O-N 3.44Å
9I36Very low56.4Low151 Ų15194.6 Ų94.677%0.77460%0.6SS**  trans-74.3109.2159.1-60.2175.4000102.3T7 G11T7-I9 PolarHBondContact O-N 3.33Å; I9-G11 PolarHBondContact O-N 3Å
10S35.6Very low58.2Low100 Ų10090.3 Ų90.370%0.69957%0.572SS**  trans-33.9132166.648.10000109.3G8 G12G8-S10 PolarHBondContact O-N 3.44Å; S10-G12 PolarHBondContact O-N 2.87Å
11G37.9Very low60.1Low93 Ų9386 Ų8696%0.95955%0.545SS*.SBendtrans-63.757.5-17500000114.8I9I9-G11 PolarHBondContact O-N 3Å
12G59.6Low63.1Low57 Ų5774.3 Ų74.359%0.58849%0.487SS*.PPolyproline II helixtrans-88.7156.6169.900000110.4S10S10-G12 PolarHBondContact O-N 2.87Å
13C77.6Confident66.1Low49 Ų4969.5 Ų69.533%0.33145%0.448SS..PPolyproline II helixtrans-67.1149.1176.9-165.90000111.4E15 N279 K280 S281C13-E15 PolarHBondContact O-N 2.87Å; C13-N279 PolarHBondContact SG-O 2.81Å; C13-K280 VanDerWaalsContact SG-C 3.53Å; C13-K280 WeakPolarHBondContact SG-CA 3.31Å; C13-S281 WeakPolarHBondContact CB-OG 3.47Å; C13-S281 PolarHBondContact O-OG 2.75Å; C13-S281 PolarHBondContact SG-N 2.78Å; C13-S281 VanDerWaalsContact SG-N 3.37Å
14R86.6Confident69Low118 Ų11864.6 Ų64.645%0.44541%0.414SS..PPolyproline II helixtrans-62.7118.1-177.4-176.6-176.1-179-164.81.4111.1W16 E19 S281R14-W16 VanDerWaalsContact C-N 3.27Å; R14-W16 PolarHBondContact O-N 2.84Å; R14-E19 WeakPolarHBondContact CG-OE1 3.48Å; R14-E19 IonicContact CZ-OE1 3.22Å; R14-E19 IonicContact CZ-OE2 2.95Å; R14-E19 VanDerWaalsContact CZ-OE2 3.32Å; R14-E19 IonicContact NE-OE1 2.84Å; R14-E19 PolarHBondContact NE-OE1 2.62Å; R14-E19 IonicContact NE-OE2 3.85Å; R14-E19 PolarHBondContact NE-OE2 2.9Å; R14-E19 IonicContact NH2-OE1 3.78Å; R14-E19 IonicContact NH2-OE2 2.78Å; R14-E19 PolarHBondContact NH2-OE2 3.16Å; R14-S281 PolarHBondContact O-OG 3.05Å
15E91.6Very high72Confident84 Ų8458 Ų5839%0.39337%0.374SS..  trans-78.573.5172.2-63.5176.398.500110.7C13 W17 K18C13-E15 PolarHBondContact O-N 2.87Å; E15-W17 HydrophobicContact CB-CD2 4.33Å; E15-W17 HydrophobicContact CB-CH2 4.08Å; E15-W17 HydrophobicContact CB-CZ2 3.64Å; E15-W17 HydrophobicContact CG-CH2 3.94Å; E15-W17 HydrophobicContact CG-CZ2 3.6Å; E15-W17 PolarHBondContact O-N 2.97Å; E15-W17 VanDerWaalsContact O-N 3.08Å; E15-K18 HydrophobicContact CB-CD 3.9Å; E15-K18 HydrophobicContact CB-CG 4.04Å; E15-K18 WeakPolarHBondContact O-CB 3.37Å; E15-K18 WeakPolarHBondContact O-CG 3.34Å; E15-K18 PolarHBondContact O-N 3.2Å; E15-K18 WeakPolarHBondContact OE1-CE 3.35Å; E15-K18 IonicContact OE1-NZ 3.52Å; E15-K18 PolarHBondContact OE1-NZ 3.09Å; E15-K18 VanDerWaalsContact OE2-CE 3.28Å; E15-K18 WeakPolarHBondContact OE2-CE 3.25Å; E15-K18 IonicContact OE2-NZ 3.88Å; E15-K18 PolarHBondContact OE2-NZ 3.43Å
16W94.8Very high75.1Confident6 Ų652.6 Ų52.62%0.02334%0.34CS..G310 helixtrans-57.2-28-170.354.4-100.6000114.5R14 K18 E19 T20 A58 F105 V107 D209 S281 F283R14-W16 VanDerWaalsContact C-N 3.27Å; R14-W16 PolarHBondContact O-N 2.84Å; W16-K18 PolarHBondContact O-N 3.36Å; W16-K18 VanDerWaalsContact O-N 3.17Å; W16-E19 PolarHBondContact O-N 2.77Å; W16-T20 HydrophobicContact CE3-CG2 4.49Å; W16-A58 HydrophobicContact CE3-CB 4.09Å; W16-A58 HydrophobicContact CH2-CB 4.41Å; W16-A58 HydrophobicContact CZ3-CB 3.56Å; W16-F105 HydrophobicContact CB-CD1 4.44Å; W16-F105 HydrophobicContact CB-CD2 3.85Å; W16-F105 HydrophobicContact CB-CE1 4.01Å; W16-F105 HydrophobicContact CB-CE2 3.38Å; W16-F105 HydrophobicContact CB-CG 4.37Å; W16-F105 HydrophobicContact CB-CZ 3.46Å; W16-F105 VanDerWaalsContact CB-CZ 3.46Å; W16-F105 AromaticContact CD1-CD1 3.71Å; W16-F105 AromaticContact CD1-CE1 3.6Å; W16-F105 AromaticContact CD1-CZ 3.99Å; W16-F105 HydrophobicContact CD2-CB 4.07Å; W16-F105 AromaticContact CD2-CD1 3.97Å; W16-F105 HydrophobicContact CD2-CD1 3.97Å; W16-F105 AromaticContact CD2-CD2 3.78Å; W16-F105 HydrophobicContact CD2-CD2 3.78Å; W16-F105 HydrophobicContact CD2-CE1 4.4Å; W16-F105 HydrophobicContact CD2-CE2 4.25Å; W16-F105 AromaticContact CD2-CG 3.64Å; W16-F105 HydrophobicContact CD2-CG 3.64Å; W16-F105 AromaticContact CE2-CD1 3.99Å; W16-F105 AromaticContact CE2-CG 3.93Å; W16-F105 HydrophobicContact CE3-CB 4.1Å; W16-F105 AromaticContact CE3-CD2 3.89Å; W16-F105 HydrophobicContact CE3-CD2 3.89Å; W16-F105 AromaticContact CE3-CG 3.98Å; W16-F105 HydrophobicContact CE3-CG 3.98Å; W16-F105 AromaticContact CG-CD1 3.8Å; W16-F105 HydrophobicContact CG-CD1 3.8Å; W16-F105 AromaticContact CG-CD2 3.78Å; W16-F105 HydrophobicContact CG-CD2 3.78Å; W16-F105 AromaticContact CG-CE1 3.74Å; W16-F105 HydrophobicContact CG-CE1 3.74Å; W16-F105 AromaticContact CG-CE2 3.75Å; W16-F105 HydrophobicContact CG-CE2 3.75Å; W16-F105 AromaticContact CG-CG 3.82Å; W16-F105 HydrophobicContact CG-CG 3.82Å; W16-F105 AromaticContact CG-CZ 3.72Å; W16-F105 HydrophobicContact CG-CZ 3.72Å; W16-F105 HydrophobicContact CH2-CB 4.24Å; W16-F105 HydrophobicContact CZ2-CB 4.13Å; W16-F105 HydrophobicContact CZ2-CG 4.47Å; W16-F105 HydrophobicContact CZ3-CB 4.23Å; W16-F105 AromaticContact NE1-CD1 3.81Å; W16-V107 HydrophobicContact CH2-CG2 3.74Å; W16-V107 HydrophobicContact CZ2-CG2 4.44Å; W16-D209 HydrophobicContact CZ2-CB 4.01Å; W16-S281 PolarHBondContact NE1-O 3.19Å; W16-F283 HydrophobicContact CH2-CB 3.49Å; W16-F283 VanDerWaalsContact CH2-CB 3.49Å; W16-F283 HydrophobicContact CH2-CD1 4.15Å; W16-F283 HydrophobicContact CH2-CD2 4.14Å; W16-F283 AromaticContact CH2-CG 3.67Å; W16-F283 HydrophobicContact CH2-CG 3.67Å; W16-F283 HydrophobicContact CZ2-CB 3.22Å; W16-F283 AromaticContact CZ2-CG 3.95Å; W16-F283 HydrophobicContact CZ2-CG 3.95Å
17W94.7Very high78Confident18 Ų1847.9 Ų47.97%0.06831%0.307CS..G310 helixtrans-63.9-19.3178.856.984.6000113.3E15 E19 F283 T304 T375E15-W17 HydrophobicContact CB-CD2 4.33Å; E15-W17 HydrophobicContact CB-CH2 4.08Å; E15-W17 HydrophobicContact CB-CZ2 3.64Å; E15-W17 HydrophobicContact CG-CH2 3.94Å; E15-W17 HydrophobicContact CG-CZ2 3.6Å; E15-W17 PolarHBondContact O-N 2.97Å; E15-W17 VanDerWaalsContact O-N 3.08Å; W17-E19 VanDerWaalsContact C-N 3.31Å; W17-F283 HydrophobicContact CB-CD2 3.79Å; W17-F283 HydrophobicContact CB-CE2 3.97Å; W17-F283 AromaticContact CD2-CD2 3.9Å; W17-F283 HydrophobicContact CD2-CD2 3.9Å; W17-F283 HydrophobicContact CE3-CB 4.04Å; W17-F283 AromaticContact CE3-CD2 3.83Å; W17-F283 HydrophobicContact CE3-CD2 3.83Å; W17-F283 HydrophobicContact CE3-CG 4.44Å; W17-F283 AromaticContact CG-CD2 3.89Å; W17-F283 HydrophobicContact CG-CD2 3.89Å; W17-F283 HydrophobicContact CG-CE2 4.2Å; W17-F283 HydrophobicContact CZ3-CB 4.33Å; W17-T304 HydrophobicContact CD2-CG2 3.75Å; W17-T304 HydrophobicContact CG-CG2 3.88Å; W17-T304 HydrophobicContact CZ2-CG2 3.88Å; W17-T304 VanDerWaalsContact NE1-CG2 3.28Å; W17-T375 PolarHBondContact O-OG1 2.95Å
18K92Very high81.2Confident49 Ų4943 Ų4321%0.21328%0.275CS..G310 helixtrans-75.5-21.6175.6-57-170.4173174.50112.6E15 W16 W339E15-K18 HydrophobicContact CB-CD 3.9Å; E15-K18 HydrophobicContact CB-CG 4.04Å; E15-K18 WeakPolarHBondContact O-CB 3.37Å; E15-K18 WeakPolarHBondContact O-CG 3.34Å; E15-K18 PolarHBondContact O-N 3.2Å; E15-K18 WeakPolarHBondContact OE1-CE 3.35Å; E15-K18 IonicContact OE1-NZ 3.52Å; E15-K18 PolarHBondContact OE1-NZ 3.09Å; E15-K18 VanDerWaalsContact OE2-CE 3.28Å; E15-K18 WeakPolarHBondContact OE2-CE 3.25Å; E15-K18 IonicContact OE2-NZ 3.88Å; E15-K18 PolarHBondContact OE2-NZ 3.43Å; W16-K18 PolarHBondContact O-N 3.36Å; W16-K18 VanDerWaalsContact O-N 3.17Å; K18-W339 HydrophobicContact CB-CH2 3.69Å; K18-W339 HydrophobicContact CB-CZ2 3.47Å; K18-W339 VanDerWaalsContact CB-CZ2 3.47Å; K18-W339 HydrophobicContact CB-CZ3 4.44Å; K18-W339 HydrophobicContact CD-CD2 4.21Å; K18-W339 HydrophobicContact CD-CE3 3.81Å; K18-W339 HydrophobicContact CD-CH2 3.65Å; K18-W339 HydrophobicContact CD-CZ2 4.06Å; K18-W339 HydrophobicContact CD-CZ3 3.51Å; K18-W339 VanDerWaalsContact CE-CE3 3.43Å; K18-W339 HydrophobicContact CG-CD2 3.93Å; K18-W339 HydrophobicContact CG-CE3 4.05Å; K18-W339 HydrophobicContact CG-CH2 3.63Å; K18-W339 HydrophobicContact CG-CZ2 3.49Å; K18-W339 VanDerWaalsContact CG-CZ2 3.49Å; K18-W339 HydrophobicContact CG-CZ3 3.91Å
19E89.1Confident84.5Confident63 Ų6339.2 Ų39.229%0.29424%0.236SC..SBendtrans-104.9-2.4-169.7-57.2-178.8-150.400113.7R14 W16 W17 Y482R14-E19 WeakPolarHBondContact CG-OE1 3.48Å; R14-E19 IonicContact CZ-OE1 3.22Å; R14-E19 IonicContact CZ-OE2 2.95Å; R14-E19 VanDerWaalsContact CZ-OE2 3.32Å; R14-E19 IonicContact NE-OE1 2.84Å; R14-E19 PolarHBondContact NE-OE1 2.62Å; R14-E19 IonicContact NE-OE2 3.85Å; R14-E19 PolarHBondContact NE-OE2 2.9Å; R14-E19 IonicContact NH2-OE1 3.78Å; R14-E19 IonicContact NH2-OE2 2.78Å; R14-E19 PolarHBondContact NH2-OE2 3.16Å; W16-E19 PolarHBondContact O-N 2.77Å; W17-E19 VanDerWaalsContact C-N 3.31Å; E19-Y482 HydrophobicContact CG-CE1 4.23Å
20T94.1Very high87.5Confident8 Ų832 Ų325%0.04920%0.199CC..SBendtrans-145.3-177.7-176.5-162.90000111.8W16 K57 A58 R475W16-T20 HydrophobicContact CE3-CG2 4.49Å; T20-K57 HydrophobicContact CG2-CB 4.03Å; T20-K57 WeakPolarHBondContact OG1-CB 3.38Å; T20-K57 PolarHBondContact OG1-N 3.04Å; T20-A58 HydrophobicContact CG2-CB 3.86Å; T20-R475 PolarHBondContact O-NH2 2.79Å
21I97.5Very high90.5Very high2 Ų228.4 Ų28.41%0.0117%0.171CC..  trans-100.5162.7167.269.5159.5000109V56 L370 A376 C378 F468 L472 R475I21-V56 HydrophobicContact CD1-CG2 3.86Å; I21-V56 HydrophobicContact CG1-CG1 4.34Å; I21-V56 HydrophobicContact CG1-CG2 3.98Å; I21-L370 HydrophobicContact CG2-CD2 3.75Å; I21-A376 WeakPolarHBondContact CA-O 3.47Å; I21-A376 HydrophobicContact CB-CB 4.37Å; I21-A376 WeakPolarHBondContact CB-O 3.3Å; I21-A376 HydrophobicContact CG2-CB 3.87Å; I21-C378 HydrophobicContact CD1-CB 3.98Å; I21-F468 HydrophobicContact CD1-CE1 4.27Å; I21-F468 HydrophobicContact CD1-CZ 3.92Å; I21-L472 HydrophobicContact CD1-CD2 4.08Å; I21-L472 HydrophobicContact CG1-CD2 4.24Å; I21-L472 HydrophobicContact CG2-CD2 3.66Å; I21-R475 VanDerWaalsContact CG2-NE 3.29Å
22I98.6Very high93.4Very high0 Ų024 Ų240%013%0.125CC..EExtended strand (participates in β ladder)trans-101.4119165.5-59.5176.4000107.4A58 W60 F283 M285 F305 T375 A376 I377 C378I22-A58 HydrophobicContact CG1-CB 4.18Å; I22-W60 HydrophobicContact CG2-CB 3.51Å; I22-F283 HydrophobicContact CD1-CD1 4.46Å; I22-F283 HydrophobicContact CD1-CE1 3.64Å; I22-F283 HydrophobicContact CD1-CE2 3.95Å; I22-F283 HydrophobicContact CD1-CZ 3.35Å; I22-M285 HydrophobicContact CD1-SD 4.36Å; I22-F305 HydrophobicContact CD1-CZ 4.18Å; I22-T375 HydrophobicContact CD1-CG2 4.11Å; I22-T375 HydrophobicContact CG1-CG2 3.96Å; I22-A376 PolarHBondContact N-O 3.3Å; I22-I377 HydrophobicContact CB-CD1 3.68Å; I22-I377 HydrophobicContact CD1-CD1 3.79Å; I22-I377 HydrophobicContact CG1-CD1 4.05Å; I22-I377 HydrophobicContact CG2-CD1 4.42Å; I22-I377 WeakPolarHBondContact O-CA 3.11Å; I22-C378 PolarHBondContact O-N 2.98Å
23Y98.8Very high95.2Very high0 Ų024 Ų240%011%0.114CC..EExtended strand (participates in β ladder)trans-97.1112.2176-170-76.3000108.8I25 F30 F51 V56 A58 L59 W60 C378 Y380 E383Y23-I25 HydrophobicContact CD1-CG1 3.79Å; Y23-I25 HydrophobicContact CE1-CG1 4.03Å; Y23-F30 HydrophobicContact CE1-CE2 4.32Å; Y23-F51 AromaticContact CD1-CE1 3.67Å; Y23-F51 HydrophobicContact CD1-CE1 3.67Å; Y23-F51 HydrophobicContact CD1-CZ 4.27Å; Y23-F51 HydrophobicContact CD2-CE1 4.42Å; Y23-F51 AromaticContact CE1-CE1 3.73Å; Y23-F51 HydrophobicContact CE1-CE1 3.73Å; Y23-F51 HydrophobicContact CE1-CZ 4.26Å; Y23-F51 HydrophobicContact CE2-CE1 4.47Å; Y23-F51 HydrophobicContact CG-CE1 4.02Å; Y23-V56 HydrophobicContact CD2-CG2 4.34Å; Y23-V56 HydrophobicContact CG-CG1 4.43Å; Y23-A58 PolarHBondContact N-O 3.03Å; Y23-L59 WeakPolarHBondContact O-CA 3.41Å; Y23-W60 PolarHBondContact O-N 3.42Å; Y23-C378 CarbonylContact C-O 3.5Å; Y23-C378 WeakPolarHBondContact CA-O 3.36Å; Y23-C378 HydrophobicContact CD2-CB 4.37Å; Y23-Y380 WeakPolarHBondContact OH-CA 3.13Å; Y23-Y380 WeakPolarHBondContact OH-CB 3.37Å; Y23-E383 HydrophobicContact CE2-CG 4.49Å; Y23-E383 PolarHBondContact OH-OE1 3.48Å; Y23-E383 PolarHBondContact OH-OE2 2.98Å
24Q98.8Very high96.2Very high0 Ų025.1 Ų25.10%012%0.122CC..EExtended strand (participates in β ladder)trans-81123.1179.1-179.7-178.330.700110.6W60 H347 C378 Y379 Y380Q24-W60 CarbonylContact C-O 3.21Å; Q24-W60 VanDerWaalsContact CA-O 3.28Å; Q24-W60 WeakPolarHBondContact CA-O 3.44Å; Q24-W60 HydrophobicContact CB-CD2 4.21Å; Q24-W60 HydrophobicContact CB-CE3 3.68Å; Q24-W60 HydrophobicContact CB-CZ3 4.2Å; Q24-W60 VanDerWaalsContact CD-CZ3 3.41Å; Q24-W60 HydrophobicContact CG-CD2 3.88Å; Q24-W60 HydrophobicContact CG-CE3 3.65Å; Q24-W60 HydrophobicContact CG-CG 4.47Å; Q24-W60 HydrophobicContact CG-CH2 4.42Å; Q24-W60 HydrophobicContact CG-CZ3 3.96Å; Q24-W60 VanDerWaalsContact NE2-CZ3 3.29Å; Q24-H347 PolarHBondContact NE2-CE1 2.83Å; Q24-H347 PolarHBondContact NE2-ND1 3.13Å; Q24-C378 PolarHBondContact N-O 3.13Å; Q24-Y379 HydrophobicContact CB-CD2 4.21Å; Q24-Y379 HydrophobicContact CG-CD2 3.93Å; Q24-Y379 HydrophobicContact CG-CE2 4.4Å; Q24-Y379 VanDerWaalsContact OE1-CD2 3.31Å; Q24-Y380 WeakPolarHBondContact O-CB 3.48Å; Q24-Y380 PolarHBondContact O-N 2.82Å
25I98.9Very high96.6Very high0 Ų020.4 Ų20.40%011%0.11CC..EExtended strand (participates in β ladder)trans-108.5131.2177.2-59.1178.4000108.5Y23 P27 F30 I44 F51 L59 W60 I61 S62Y23-I25 HydrophobicContact CD1-CG1 3.79Å; Y23-I25 HydrophobicContact CE1-CG1 4.03Å; I25-P27 WeakPolarHBondContact O-CD 3.4Å; I25-F30 HydrophobicContact CD1-CE1 4.47Å; I25-F30 HydrophobicContact CD1-CE2 4.47Å; I25-F30 HydrophobicContact CD1-CZ 4.36Å; I25-F30 HydrophobicContact CG1-CD2 4.43Å; I25-F30 HydrophobicContact CG1-CE2 4.43Å; I25-F30 HydrophobicContact CG2-CB 3.56Å; I25-F30 HydrophobicContact CG2-CD1 4.14Å; I25-F30 HydrophobicContact CG2-CD2 3.76Å; I25-F30 HydrophobicContact CG2-CG 3.54Å; I25-I44 HydrophobicContact CD1-CD1 4.38Å; I25-I44 HydrophobicContact CD1-CG1 4.41Å; I25-I44 HydrophobicContact CD1-CG2 3.84Å; I25-I44 HydrophobicContact CG2-CD1 3.93Å; I25-I44 HydrophobicContact CG2-CG1 4.21Å; I25-F51 HydrophobicContact CD1-CE2 4.09Å; I25-F51 HydrophobicContact CD1-CZ 3.59Å; I25-F51 HydrophobicContact CG1-CZ 4.34Å; I25-L59 HydrophobicContact CD1-CB 4.25Å; I25-L59 HydrophobicContact CD1-CD1 3.96Å; I25-L59 HydrophobicContact CD1-CD2 4.23Å; I25-L59 HydrophobicContact CD1-CG 4.37Å; I25-W60 PolarHBondContact N-O 2.93Å; I25-I61 HydrophobicContact CB-CG2 4.24Å; I25-I61 HydrophobicContact CD1-CG2 4.43Å; I25-S62 PolarHBondContact O-N 2.68Å
26Y98.6Very high96.9Very high3 Ų319.8 Ų19.81%0.01211%0.11CC..  trans-95.5101.2164.7-164.2-103.7000108.3R28 S29 F30 F72 H347 R420 W442Y26-R28 VanDerWaalsContact C-N 3.33Å; Y26-R28 HydrophobicContact CD1-CB 4.14Å; Y26-R28 HydrophobicContact CE1-CB 3.93Å; Y26-R28 HydrophobicContact CE1-CG 4.44Å; Y26-R28 PolarHBondContact O-N 3.41Å; Y26-S29 PolarHBondContact O-N 3.21Å; Y26-F30 PolarHBondContact O-N 3.46Å; Y26-F72 VanDerWaalsContact OH-CB 3.29Å; Y26-F72 WeakPolarHBondContact OH-CB 3.39Å; Y26-F72 WeakPolarHBondContact OH-CD2 3.45Å; Y26-H347 HydrophobicContact CD2-CB 3.87Å; Y26-H347 HydrophobicContact CE2-CB 4.21Å; Y26-R420 HydrophobicContact CD1-CB 4.26Å; Y26-R420 HydrophobicContact CD1-CG 4.41Å; Y26-R420 HydrophobicContact CE1-CB 4.01Å; Y26-R420 HydrophobicContact CE1-CG 4.09Å; Y26-R420 HydrophobicContact CE2-CG 4.26Å; Y26-W442 HydrophobicContact CD1-CZ2 4.41Å; Y26-W442 HydrophobicContact CE1-CH2 4.02Å; Y26-W442 AromaticContact CE1-CZ2 3.75Å; Y26-W442 HydrophobicContact CE1-CZ2 3.75Å
27P98.6Very high97Very high3 Ų319.6 Ų19.62%0.01911%0.11CC..Hα-helixtrans-53.8-45.9-164.4-29.836.9000113.5I25 S29 F30 G39 I61 V64 F86I25-P27 WeakPolarHBondContact O-CD 3.4Å; P27-S29 PolarHBondContact O-N 2.6Å; P27-F30 PolarHBondContact O-N 2.87Å; P27-F30 VanDerWaalsContact O-N 3.08Å; P27-G39 CarbonylContact C-O 3.45Å; P27-G39 CarbonylContact O-C 3.59Å; P27-G39 VanDerWaalsContact O-C 3.27Å; P27-G39 WeakPolarHBondContact O-CA 3.41Å; P27-I61 HydrophobicContact CG-CB 4.35Å; P27-V64 HydrophobicContact CB-CG1 4.03Å; P27-V64 HydrophobicContact CG-CG1 3.66Å; P27-F86 HydrophobicContact CB-CD1 4.16Å; P27-F86 HydrophobicContact CB-CE1 4.03Å
28R98.2Very high97.2Very high19 Ų1920 Ų207%0.07211%0.113CC..Hα-helixtrans-52-27.3179.3-68.6179.5157.8-104.2-8.7114.3Y26 I38 G39 M69 F86 F434 W442Y26-R28 VanDerWaalsContact C-N 3.33Å; Y26-R28 HydrophobicContact CD1-CB 4.14Å; Y26-R28 HydrophobicContact CE1-CB 3.93Å; Y26-R28 HydrophobicContact CE1-CG 4.44Å; Y26-R28 PolarHBondContact O-N 3.41Å; R28-I38 HydrophobicContact CB-CG2 3.98Å; R28-I38 HydrophobicContact CG-CG2 3.79Å; R28-G39 PolarHBondContact O-N 3.04Å; R28-M69 VanDerWaalsContact NH2-CB 3.32Å; R28-M69 PolarHBondContact NH2-SD 3.48Å; R28-F86 HydrophobicContact CG-CE1 3.65Å; R28-F86 HydrophobicContact CG-CZ 3.78Å; R28-F434 WeakPolarHBondContact O-CZ 3.38Å; R28-W442 HydrophobicContact CB-CZ2 3.94Å; R28-W442 VanDerWaalsContact O-CD1 3.22Å; R28-W442 PolarHBondContact O-NE1 3.2Å
29S98.3Very high97.5Very high0 Ų017.7 Ų17.70%010%0.103CC..Hα-helixtrans-116.32.5-173.2-68.90000113.7Y26 P27 Y380 R420 P422 L423 F434 W442Y26-S29 PolarHBondContact O-N 3.21Å; P27-S29 PolarHBondContact O-N 2.6Å; S29-Y380 WeakPolarHBondContact CB-OH 3.26Å; S29-R420 VanDerWaalsContact CB-O 3.23Å; S29-R420 WeakPolarHBondContact CB-O 3.14Å; S29-R420 PolarHBondContact OG-O 2.87Å; S29-P422 WeakPolarHBondContact O-CA 3.35Å; S29-L423 PolarHBondContact O-N 3.04Å; S29-F434 VanDerWaalsContact C-CE2 3.46Å; S29-F434 WeakPolarHBondContact O-CE2 3.43Å; S29-W442 VanDerWaalsContact OG-CZ2 3.31Å; S29-W442 WeakPolarHBondContact OG-CZ2 3.47Å; S29-W442 PolarHBondContact OG-NE1 2.9Å
30F98.5Very high98Very high1 Ų115 Ų150%0.0049%0.09CC..Hα-helixtrans-82.4-62.8-176.1-169.3-108.2000112Y23 I25 Y26 P27 I44 K47 F51 Y380 L423 W425Y23-F30 HydrophobicContact CE1-CE2 4.32Å; I25-F30 HydrophobicContact CD1-CE1 4.47Å; I25-F30 HydrophobicContact CD1-CE2 4.47Å; I25-F30 HydrophobicContact CD1-CZ 4.36Å; I25-F30 HydrophobicContact CG1-CD2 4.43Å; I25-F30 HydrophobicContact CG1-CE2 4.43Å; I25-F30 HydrophobicContact CG2-CB 3.56Å; I25-F30 HydrophobicContact CG2-CD1 4.14Å; I25-F30 HydrophobicContact CG2-CD2 3.76Å; I25-F30 HydrophobicContact CG2-CG 3.54Å; Y26-F30 PolarHBondContact O-N 3.46Å; P27-F30 PolarHBondContact O-N 2.87Å; P27-F30 VanDerWaalsContact O-N 3.08Å; F30-I44 HydrophobicContact CD1-CB 4.39Å; F30-I44 HydrophobicContact CD1-CG1 3.74Å; F30-I44 HydrophobicContact CE1-CB 4.49Å; F30-I44 HydrophobicContact CE1-CG1 4.28Å; F30-K47 HydrophobicContact CE1-CB 3.9Å; F30-K47 HydrophobicContact CE1-CG 4.12Å; F30-K47 HydrophobicContact CZ-CB 4.21Å; F30-F51 HydrophobicContact CE1-CE2 4.32Å; F30-F51 HydrophobicContact CE1-CZ 4.12Å; F30-F51 AromaticContact CE2-CZ 3.98Å; F30-F51 HydrophobicContact CE2-CZ 3.98Å; F30-F51 HydrophobicContact CZ-CE1 4.26Å; F30-F51 AromaticContact CZ-CE2 3.93Å; F30-F51 HydrophobicContact CZ-CE2 3.93Å; F30-F51 AromaticContact CZ-CZ 3.35Å; F30-F51 HydrophobicContact CZ-CZ 3.35Å; F30-Y380 HydrophobicContact CD2-CD2 4.49Å; F30-L423 HydrophobicContact CD2-CD2 4.13Å; F30-L423 HydrophobicContact CE2-CD2 3.98Å; F30-W425 HydrophobicContact CD1-CZ2 4.2Å; F30-W425 HydrophobicContact CD2-CZ2 4.24Å; F30-W425 HydrophobicContact CE1-CH2 4.11Å; F30-W425 AromaticContact CE1-CZ2 3.68Å; F30-W425 HydrophobicContact CE1-CZ2 3.68Å; F30-W425 HydrophobicContact CE2-CH2 4.03Å; F30-W425 AromaticContact CE2-CZ2 3.72Å; F30-W425 HydrophobicContact CE2-CZ2 3.72Å; F30-W425 HydrophobicContact CG-CZ2 4.46Å; F30-W425 AromaticContact CZ-CH2 3.55Å; F30-W425 HydrophobicContact CZ-CH2 3.55Å; F30-W425 AromaticContact CZ-CZ2 3.41Å; F30-W425 HydrophobicContact CZ-CZ2 3.41Å; F30-W425 VanDerWaalsContact CZ-CZ2 3.41Å; F30-W425 PolarHBondContact O-NE1 2.73Å
31K98.4Very high98.2Very high24 Ų2414.6 Ų14.610%0.1049%0.088CC..  trans-161.5126176.3178.473.6-174.693.10109.7T33 G39 D40 W425 G433 F434K31-T33 HydrophobicContact CG-CG2 4.22Å; K31-G39 VanDerWaalsContact C-CA 3.43Å; K31-G39 CarbonylContact O-C 3.6Å; K31-G39 WeakPolarHBondContact O-CA 3.2Å; K31-D40 PolarHBondContact O-N 3.19Å; K31-W425 HydrophobicContact CD-CG 4.32Å; K31-G433 WeakPolarHBondContact CD-O 3.32Å; K31-G433 WeakPolarHBondContact CE-O 3.25Å; K31-G433 PolarHBondContact NZ-O 3.22Å; K31-F434 PolarHBondContact NZ-O 2.83Å
32D98.4Very high98.3Very high1 Ų116.4 Ų16.41%0.00510%0.098CC..  trans-92128.8171.6174.917.8000109.9S34 G35 N36 G37 I38 F434 T435D32-S34 WeakPolarHBondContact OD1-CA 3.43Å; D32-S34 PolarHBondContact OD1-N 2.5Å; D32-S34 PolarHBondContact OD1-OG 3.09Å; D32-G35 PolarHBondContact OD1-N 2.82Å; D32-G35 VanDerWaalsContact OD2-CA 3.31Å; D32-G35 WeakPolarHBondContact OD2-CA 3.46Å; D32-G35 PolarHBondContact OD2-N 3.19Å; D32-N36 PolarHBondContact OD2-N 3.3Å; D32-N36 VanDerWaalsContact OD2-N 3.09Å; D32-G37 WeakPolarHBondContact OD2-CA 3.23Å; D32-G37 PolarHBondContact OD2-N 3.09Å; D32-I38 VanDerWaalsContact CB-O 3.26Å; D32-I38 WeakPolarHBondContact CB-O 3.47Å; D32-I38 VanDerWaalsContact CG-O 3.23Å; D32-F434 HydrophobicContact CB-CE1 4.43Å; D32-F434 HydrophobicContact CB-CZ 4.25Å; D32-F434 PolarHBondContact N-O 3.14Å; D32-T435 WeakPolarHBondContact OD2-CB 3.44Å; D32-T435 PolarHBondContact OD2-OG1 2.66Å
33T97.9Very high98.3Very high56 Ų5616.4 Ų16.434%0.34410%0.098SC..SBendtrans-116.2-13.6173.966.60000112.8K31 D40 N42 G43K31-T33 HydrophobicContact CG-CG2 4.22Å; T33-D40 PolarHBondContact N-OD2 2.81Å; T33-D40 VanDerWaalsContact OG1-CG 3.25Å; T33-D40 PolarHBondContact OG1-OD1 2.83Å; T33-D40 PolarHBondContact OG1-OD2 3.3Å; T33-N42 WeakPolarHBondContact OG1-CB 3.28Å; T33-G43 VanDerWaalsContact CG2-CA 3.43Å
34S97.2Very high98.3Very high72 Ų7216.4 Ų16.450%0.50310%0.098SC..SBendtrans-81.1-21.8176.872.90000113.8D32 N36 D40D32-S34 WeakPolarHBondContact OD1-CA 3.43Å; D32-S34 PolarHBondContact OD1-N 2.5Å; D32-S34 PolarHBondContact OD1-OG 3.09Å; S34-N36 PolarHBondContact OG-N 2.83Å; S34-N36 PolarHBondContact OG-ND2 3.03Å; S34-N36 VanDerWaalsContact OG-ND2 3.08Å; S34-N36 PolarHBondContact OG-OD1 3.45Å; S34-N36 VanDerWaalsContact OG-OD1 3.13Å; S34-D40 PolarHBondContact N-OD2 2.89Å; S34-D40 VanDerWaalsContact N-OD2 3.07Å
35G96.9Very high98.3Very high20 Ų2018.9 Ų18.921%0.20611%0.107CC..SBendtrans79.720.8-178.500000113.8D32 C437D32-G35 PolarHBondContact OD1-N 2.82Å; D32-G35 VanDerWaalsContact OD2-CA 3.31Å; D32-G35 WeakPolarHBondContact OD2-CA 3.46Å; D32-G35 PolarHBondContact OD2-N 3.19Å; G35-C437 WeakPolarHBondContact O-CA 3.43Å; G35-C437 WeakPolarHBondContact O-CB 3.38Å; G35-C437 PolarHBondContact O-SG 3.12Å; G35-C437 VanDerWaalsContact O-SG 3.35Å
36N96.9Very high98.3Very high70 Ų7023.9 Ų23.937%0.37413%0.13SC..SBendtrans-97.62.7177.870.711.6000113.7D32 S34 I38D32-N36 PolarHBondContact OD2-N 3.3Å; D32-N36 VanDerWaalsContact OD2-N 3.09Å; S34-N36 PolarHBondContact OG-N 2.83Å; S34-N36 PolarHBondContact OG-ND2 3.03Å; S34-N36 VanDerWaalsContact OG-ND2 3.08Å; S34-N36 PolarHBondContact OG-OD1 3.45Å; S34-N36 VanDerWaalsContact OG-OD1 3.13Å; N36-I38 VanDerWaalsContact C-N 3.35Å; N36-I38 WeakPolarHBondContact OD1-CA 3.43Å; N36-I38 WeakPolarHBondContact OD1-CB 3.03Å; N36-I38 PolarHBondContact OD1-N 2.79Å; N36-I38 PolarHBondContact OD1-O 2.86Å; N36-I38 VanDerWaalsContact OD1-O 3.1Å
37G97.7Very high98.2Very high2 Ų225.3 Ų25.32%0.02114%0.137CC..SBendtrans860.9179.200000114.3D32 F434 G440 W442D32-G37 WeakPolarHBondContact OD2-CA 3.23Å; D32-G37 PolarHBondContact OD2-N 3.09Å; G37-F434 VanDerWaalsContact O-CE1 3.31Å; G37-F434 WeakPolarHBondContact O-CE1 3.46Å; G37-G440 WeakPolarHBondContact CA-O 3.5Å; G37-W442 WeakPolarHBondContact O-CB 3.46Å; G37-W442 PolarHBondContact O-N 2.81Å
38I98.3Very high98.3Very high27 Ų2725.2 Ų25.214%0.13814%0.136CC..SBendtrans-123.6131.6-176.8-64.1168.1000109.3R28 D32 N36 L85 F86 W442R28-I38 HydrophobicContact CB-CG2 3.98Å; R28-I38 HydrophobicContact CG-CG2 3.79Å; D32-I38 VanDerWaalsContact CB-O 3.26Å; D32-I38 WeakPolarHBondContact CB-O 3.47Å; D32-I38 VanDerWaalsContact CG-O 3.23Å; N36-I38 VanDerWaalsContact C-N 3.35Å; N36-I38 WeakPolarHBondContact OD1-CA 3.43Å; N36-I38 WeakPolarHBondContact OD1-CB 3.03Å; N36-I38 PolarHBondContact OD1-N 2.79Å; N36-I38 PolarHBondContact OD1-O 2.86Å; N36-I38 VanDerWaalsContact OD1-O 3.1Å; I38-L85 HydrophobicContact CB-CD1 4.11Å; I38-L85 HydrophobicContact CD1-CD1 3.74Å; I38-L85 HydrophobicContact CD1-CD2 4.1Å; I38-L85 HydrophobicContact CD1-CG 4.42Å; I38-L85 HydrophobicContact CG1-CD1 4.49Å; I38-L85 HydrophobicContact CG2-CD1 4.11Å; I38-L85 HydrophobicContact CG2-CD2 4Å; I38-L85 HydrophobicContact CG2-CG 3.96Å; I38-F86 HydrophobicContact CG2-CE1 4.32Å; I38-W442 HydrophobicContact CD1-CB 4.34Å; I38-W442 HydrophobicContact CG1-CB 3.58Å; I38-W442 HydrophobicContact CG1-CG 4.01Å
39G98.6Very high98.3Very high0 Ų027.6 Ų27.60%016%0.156CC..  trans-68.8148.6179.700000114P27 R28 K31 F86P27-G39 CarbonylContact C-O 3.45Å; P27-G39 CarbonylContact O-C 3.59Å; P27-G39 VanDerWaalsContact O-C 3.27Å; P27-G39 WeakPolarHBondContact O-CA 3.41Å; R28-G39 PolarHBondContact O-N 3.04Å; K31-G39 VanDerWaalsContact C-CA 3.43Å; K31-G39 CarbonylContact O-C 3.6Å; K31-G39 WeakPolarHBondContact O-CA 3.2Å; G39-F86 VanDerWaalsContact O-CD1 3.26Å; G39-F86 WeakPolarHBondContact O-CD1 3.29Å
40D98.8Very high98.3Very high6 Ų627.9 Ų27.93%0.03216%0.157CC..  trans-135.9172.3-169.259.951.9000112.3K31 T33 S34 N42 G43 I44K31-D40 PolarHBondContact O-N 3.19Å; T33-D40 PolarHBondContact N-OD2 2.81Å; T33-D40 VanDerWaalsContact OG1-CG 3.25Å; T33-D40 PolarHBondContact OG1-OD1 2.83Å; T33-D40 PolarHBondContact OG1-OD2 3.3Å; S34-D40 PolarHBondContact N-OD2 2.89Å; S34-D40 VanDerWaalsContact N-OD2 3.07Å; D40-N42 VanDerWaalsContact C-N 3.27Å; D40-N42 PolarHBondContact O-N 2.86Å; D40-N42 WeakPolarHBondContact OD1-CB 3.35Å; D40-N42 PolarHBondContact OD1-N 2.86Å; D40-N42 VanDerWaalsContact OD1-N 3.15Å; D40-G43 PolarHBondContact O-N 3.26Å; D40-G43 PolarHBondContact OD1-N 2.99Å; D40-I44 PolarHBondContact O-N 3.07Å
41L98.9Very high98.3Very high0 Ų027.9 Ų27.90%016%0.157CC..Hα-helixtrans-63.7-33.5-177.6-68.7173.2000112.5G43 I44 R45 I61 V64 V82 F86 D91 L92 L95L41-G43 VanDerWaalsContact C-N 3.29Å; L41-G43 PolarHBondContact O-N 2.83Å; L41-I44 HydrophobicContact CD2-CD1 4.49Å; L41-I44 PolarHBondContact O-N 3.32Å; L41-R45 PolarHBondContact O-N 2.88Å; L41-I61 HydrophobicContact CD2-CD1 4.23Å; L41-V64 HydrophobicContact CD2-CG1 4.24Å; L41-V64 HydrophobicContact CD2-CG2 4.5Å; L41-V82 HydrophobicContact CD1-CG1 3.71Å; L41-V82 HydrophobicContact CD1-CG2 4.2Å; L41-F86 WeakPolarHBondContact CB-O 3.4Å; L41-F86 HydrophobicContact CG-CB 4.34Å; L41-F86 WeakPolarHBondContact CG-O 3.42Å; L41-F86 PolarHBondContact N-O 3.3Å; L41-D91 HydrophobicContact CB-CB 4.44Å; L41-D91 HydrophobicContact CD1-CB 4.28Å; L41-L92 HydrophobicContact CD1-CB 3.76Å; L41-L92 HydrophobicContact CD1-CD1 4.08Å; L41-L92 HydrophobicContact CD2-CD1 3.76Å; L41-L95 HydrophobicContact CD2-CD2 4.11Å
42N98.7Very high98.2Very high40 Ų4031.4 Ų31.421%0.21417%0.173CC..Hα-helixtrans-67.7-33.7177.7-70.7-28.5000111.1T33 D40 R45 E46 D91T33-N42 WeakPolarHBondContact OG1-CB 3.28Å; D40-N42 VanDerWaalsContact C-N 3.27Å; D40-N42 PolarHBondContact O-N 2.86Å; D40-N42 WeakPolarHBondContact OD1-CB 3.35Å; D40-N42 PolarHBondContact OD1-N 2.86Å; D40-N42 VanDerWaalsContact OD1-N 3.15Å; N42-R45 PolarHBondContact O-N 3.06Å; N42-R45 PolarHBondContact OD1-NH1 3.1Å; N42-R45 PolarHBondContact OD1-NH2 3.16Å; N42-E46 WeakPolarHBondContact O-CB 3.43Å; N42-E46 PolarHBondContact O-N 2.92Å; N42-D91 PolarHBondContact ND2-OD1 3.38Å; N42-D91 PolarHBondContact OD1-OD1 3.14Å
43G98.7Very high98.2Very high0 Ų034.2 Ų34.20%018%0.184CC..Hα-helixtrans-63.4-37.8170.300000113.4T33 D40 L41 K47T33-G43 VanDerWaalsContact CG2-CA 3.43Å; D40-G43 PolarHBondContact O-N 3.26Å; D40-G43 PolarHBondContact OD1-N 2.99Å; L41-G43 VanDerWaalsContact C-N 3.29Å; L41-G43 PolarHBondContact O-N 2.83Å; G43-K47 VanDerWaalsContact O-CG 3.32Å; G43-K47 WeakPolarHBondContact O-CG 3.32Å
44I98.9Very high98.2Very high0 Ų031.7 Ų31.70%017%0.169CC..Hα-helixtrans-65.7-46.1171.8-58.4175000110.2I25 F30 D40 L41 E46 K47 L48 L59 I61 L95I25-I44 HydrophobicContact CD1-CD1 4.38Å; I25-I44 HydrophobicContact CD1-CG1 4.41Å; I25-I44 HydrophobicContact CD1-CG2 3.84Å; I25-I44 HydrophobicContact CG2-CD1 3.93Å; I25-I44 HydrophobicContact CG2-CG1 4.21Å; F30-I44 HydrophobicContact CD1-CB 4.39Å; F30-I44 HydrophobicContact CD1-CG1 3.74Å; F30-I44 HydrophobicContact CE1-CB 4.49Å; F30-I44 HydrophobicContact CE1-CG1 4.28Å; D40-I44 PolarHBondContact O-N 3.07Å; L41-I44 HydrophobicContact CD2-CD1 4.49Å; L41-I44 PolarHBondContact O-N 3.32Å; I44-E46 PolarHBondContact O-N 3.3Å; I44-K47 PolarHBondContact O-N 2.89Å; I44-K47 VanDerWaalsContact O-N 3.1Å; I44-L48 PolarHBondContact O-N 2.87Å; I44-L59 HydrophobicContact CG2-CD1 4.08Å; I44-I61 HydrophobicContact CD1-CG2 3.81Å; I44-L95 HydrophobicContact CB-CD2 4.26Å; I44-L95 HydrophobicContact CG2-CD1 4.08Å; I44-L95 HydrophobicContact CG2-CD2 4.05Å
45R98.7Very high98.2Very high53 Ų5330.2 Ų30.220%0.216%0.164CC..Hα-helixtrans-59.5-44.2179.5-168.617368.6-139-1112.5L41 N42 K47 L48 D91 L94 L95 E98L41-R45 PolarHBondContact O-N 2.88Å; N42-R45 PolarHBondContact O-N 3.06Å; N42-R45 PolarHBondContact OD1-NH1 3.1Å; N42-R45 PolarHBondContact OD1-NH2 3.16Å; R45-K47 PolarHBondContact O-N 3.13Å; R45-K47 VanDerWaalsContact O-N 3.15Å; R45-L48 HydrophobicContact CG-CD1 4.32Å; R45-L48 VanDerWaalsContact O-CG 3.31Å; R45-L48 WeakPolarHBondContact O-CG 3.47Å; R45-L48 PolarHBondContact O-N 3.36Å; R45-D91 IonicContact NH1-OD1 3.19Å; R45-L94 VanDerWaalsContact NH1-CD2 3.31Å; R45-L95 HydrophobicContact CB-CD1 3.98Å; R45-L95 HydrophobicContact CG-CD1 4.39Å; R45-E98 WeakPolarHBondContact CD-OE1 3.22Å; R45-E98 IonicContact NE-OE1 3.89Å
46E98.3Very high98.2Very high104 Ų10429.3 Ų29.349%0.48616%0.155SC..Hα-helixtrans-57.7-30.3177.3-166.3-164.4119.400112.1N42 I44N42-E46 WeakPolarHBondContact O-CB 3.43Å; N42-E46 PolarHBondContact O-N 2.92Å; I44-E46 PolarHBondContact O-N 3.3Å
47K98.3Very high98.3Very high34 Ų3429.9 Ų29.915%0.14815%0.154CC..THydrogen-bonded Turntrans-98.711-175.2-55.2-58.4-174.2-154.80113.9F30 G43 I44 R45 S49 Y50 F51 W425F30-K47 HydrophobicContact CE1-CB 3.9Å; F30-K47 HydrophobicContact CE1-CG 4.12Å; F30-K47 HydrophobicContact CZ-CB 4.21Å; G43-K47 VanDerWaalsContact O-CG 3.32Å; G43-K47 WeakPolarHBondContact O-CG 3.32Å; I44-K47 PolarHBondContact O-N 2.89Å; I44-K47 VanDerWaalsContact O-N 3.1Å; R45-K47 PolarHBondContact O-N 3.13Å; R45-K47 VanDerWaalsContact O-N 3.15Å; K47-S49 PolarHBondContact O-N 2.82Å; K47-S49 VanDerWaalsContact O-N 3.16Å; K47-Y50 VanDerWaalsContact O-CB 3.26Å; K47-Y50 WeakPolarHBondContact O-CB 3.36Å; K47-Y50 PolarHBondContact O-N 3.3Å; K47-F51 WeakPolarHBondContact O-CD2 3.26Å; K47-F51 PolarHBondContact O-N 2.86Å; K47-W425 HydrophobicContact CB-CH2 3.73Å; K47-W425 HydrophobicContact CB-CZ2 4.15Å; K47-W425 HydrophobicContact CB-CZ3 4.31Å; K47-W425 HydrophobicContact CD-CD2 4.16Å; K47-W425 HydrophobicContact CD-CE3 3.91Å; K47-W425 HydrophobicContact CD-CH2 3.83Å; K47-W425 HydrophobicContact CD-CZ2 4.06Å; K47-W425 HydrophobicContact CD-CZ3 3.74Å; K47-W425 HydrophobicContact CG-CE3 4.46Å; K47-W425 HydrophobicContact CG-CH2 3.51Å; K47-W425 HydrophobicContact CG-CZ2 3.56Å; K47-W425 HydrophobicContact CG-CZ3 3.98Å
48L98.8Very high98.3Very high1 Ų129.8 Ų29.81%0.00515%0.153CC..Hα-helixtrans-54.2-37174-69.8179000113.1I44 R45 Y50 F51 E52 L59 L95 E98 M99 M104I44-L48 PolarHBondContact O-N 2.87Å; R45-L48 HydrophobicContact CG-CD1 4.32Å; R45-L48 VanDerWaalsContact O-CG 3.31Å; R45-L48 WeakPolarHBondContact O-CG 3.47Å; R45-L48 PolarHBondContact O-N 3.36Å; L48-Y50 PolarHBondContact O-N 3.16Å; L48-F51 HydrophobicContact CD2-CD2 4.33Å; L48-F51 PolarHBondContact O-N 3.32Å; L48-F51 VanDerWaalsContact O-N 3.14Å; L48-E52 PolarHBondContact O-N 3.43Å; L48-L59 HydrophobicContact CD2-CD1 4.27Å; L48-L95 HydrophobicContact CD1-CD1 4.24Å; L48-L95 HydrophobicContact CD2-CD1 4.08Å; L48-L95 HydrophobicContact CG-CD1 4.38Å; L48-E98 HydrophobicContact CD1-CB 3.76Å; L48-M99 HydrophobicContact CD1-CG 4.19Å; L48-M99 HydrophobicContact CD2-CG 3.56Å; L48-M99 HydrophobicContact CD2-SD 4.33Å; L48-M104 HydrophobicContact CD2-SD 4.18Å
49S98.3Very high98.3Very high69 Ų6928.5 Ų28.548%0.48315%0.146SC..Hα-helixtrans-64-25.1176.4660000114.1K47 W53K47-S49 PolarHBondContact O-N 2.82Å; K47-S49 VanDerWaalsContact O-N 3.16Å; S49-W53 WeakPolarHBondContact O-CB 3.47Å; S49-W53 PolarHBondContact O-N 3.3Å
50Y98.5Very high98.4Very high6 Ų628.7 Ų28.72%0.02415%0.147CC..Hα-helixtrans-70.6-42.8173.7168.1-110.4000111K47 L48 W53 L54 E383 W425 V454 L465K47-Y50 VanDerWaalsContact O-CB 3.26Å; K47-Y50 WeakPolarHBondContact O-CB 3.36Å; K47-Y50 PolarHBondContact O-N 3.3Å; L48-Y50 PolarHBondContact O-N 3.16Å; Y50-W53 HydrophobicContact CD2-CE3 4.29Å; Y50-W53 HydrophobicContact CE2-CE3 4.31Å; Y50-W53 HydrophobicContact CE2-CZ3 4.34Å; Y50-W53 PolarHBondContact O-N 3.34Å; Y50-L54 HydrophobicContact CD1-CD1 4.27Å; Y50-L54 HydrophobicContact CE1-CD1 3.6Å; Y50-L54 HydrophobicContact CE2-CD1 3.92Å; Y50-L54 HydrophobicContact CE2-CG 4.06Å; Y50-L54 VanDerWaalsContact CZ-CD1 3.41Å; Y50-L54 PolarHBondContact O-N 3.07Å; Y50-E383 PolarHBondContact OH-OE1 2.88Å; Y50-E383 VanDerWaalsContact OH-OE1 3.04Å; Y50-W425 AromaticContact CD1-CH2 3.9Å; Y50-W425 HydrophobicContact CD1-CH2 3.9Å; Y50-W425 AromaticContact CD1-CZ3 3.99Å; Y50-W425 HydrophobicContact CD1-CZ3 3.99Å; Y50-W425 HydrophobicContact CD2-CZ3 4.43Å; Y50-W425 HydrophobicContact CE1-CH2 4.29Å; Y50-W425 HydrophobicContact CE1-CZ3 4.39Å; Y50-W425 HydrophobicContact CG-CH2 4.33Å; Y50-W425 AromaticContact CG-CZ3 3.99Å; Y50-W425 HydrophobicContact CG-CZ3 3.99Å; Y50-V454 HydrophobicContact CD2-CG1 3.8Å; Y50-V454 HydrophobicContact CE2-CG1 3.48Å; Y50-V454 VanDerWaalsContact CE2-CG1 3.48Å; Y50-L465 HydrophobicContact CE2-CD1 4.11Å; Y50-L465 HydrophobicContact CE2-CD2 4.28Å; Y50-L465 VanDerWaalsContact OH-CD1 3.27Å; Y50-L465 WeakPolarHBondContact OH-CD1 3.43Å
51F98.5Very high98.4Very high0 Ų028.5 Ų28.50%015%0.146CC..Hα-helixtrans-65.7-39.8175.3-60.2-58.8000112.1Y23 I25 F30 K47 L48 W53 L54 G55 V56 L59 M104Y23-F51 AromaticContact CD1-CE1 3.67Å; Y23-F51 HydrophobicContact CD1-CE1 3.67Å; Y23-F51 HydrophobicContact CD1-CZ 4.27Å; Y23-F51 HydrophobicContact CD2-CE1 4.42Å; Y23-F51 AromaticContact CE1-CE1 3.73Å; Y23-F51 HydrophobicContact CE1-CE1 3.73Å; Y23-F51 HydrophobicContact CE1-CZ 4.26Å; Y23-F51 HydrophobicContact CE2-CE1 4.47Å; Y23-F51 HydrophobicContact CG-CE1 4.02Å; I25-F51 HydrophobicContact CD1-CE2 4.09Å; I25-F51 HydrophobicContact CD1-CZ 3.59Å; I25-F51 HydrophobicContact CG1-CZ 4.34Å; F30-F51 HydrophobicContact CE1-CE2 4.32Å; F30-F51 HydrophobicContact CE1-CZ 4.12Å; F30-F51 AromaticContact CE2-CZ 3.98Å; F30-F51 HydrophobicContact CE2-CZ 3.98Å; F30-F51 HydrophobicContact CZ-CE1 4.26Å; F30-F51 AromaticContact CZ-CE2 3.93Å; F30-F51 HydrophobicContact CZ-CE2 3.93Å; F30-F51 AromaticContact CZ-CZ 3.35Å; F30-F51 HydrophobicContact CZ-CZ 3.35Å; K47-F51 WeakPolarHBondContact O-CD2 3.26Å; K47-F51 PolarHBondContact O-N 2.86Å; L48-F51 HydrophobicContact CD2-CD2 4.33Å; L48-F51 PolarHBondContact O-N 3.32Å; L48-F51 VanDerWaalsContact O-N 3.14Å; F51-W53 VanDerWaalsContact C-N 3.35Å; F51-W53 PolarHBondContact O-N 3.18Å; F51-L54 PolarHBondContact O-N 3.49Å; F51-G55 PolarHBondContact O-N 3.21Å; F51-V56 HydrophobicContact CB-CB 4.15Å; F51-V56 HydrophobicContact CD1-CB 4.18Å; F51-V56 HydrophobicContact CD1-CG1 4.17Å; F51-V56 PolarHBondContact O-N 2.6Å; F51-L59 HydrophobicContact CD1-CD2 3.8Å; F51-L59 HydrophobicContact CD2-CD1 3.86Å; F51-L59 HydrophobicContact CD2-CD2 3.93Å; F51-L59 HydrophobicContact CE1-CD2 3.77Å; F51-L59 HydrophobicContact CE2-CD1 3.67Å; F51-L59 HydrophobicContact CE2-CD2 3.91Å; F51-L59 HydrophobicContact CE2-CG 4.47Å; F51-L59 HydrophobicContact CG-CD2 3.89Å; F51-L59 HydrophobicContact CZ-CD1 4.26Å; F51-L59 HydrophobicContact CZ-CD2 3.82Å; F51-M104 HydrophobicContact CB-CE 3.86Å; F51-M104 HydrophobicContact CB-SD 4.37Å
52E97.8Very high98.3Very high98 Ų9828.6 Ų28.646%0.45815%0.147SC..Hα-helixtrans-58.7-46.3171.8-70.1-178121.400111.5L48 L54 G55 R102 M104L48-E52 PolarHBondContact O-N 3.43Å; E52-L54 VanDerWaalsContact C-N 3.32Å; E52-L54 PolarHBondContact O-N 2.82Å; E52-G55 PolarHBondContact O-N 3.45Å; E52-R102 WeakPolarHBondContact OE1-CD 3.36Å; E52-R102 WeakPolarHBondContact OE1-CG 3.29Å; E52-R102 IonicContact OE1-NE 3.86Å; E52-R102 IonicContact OE2-NE 3.72Å; E52-M104 HydrophobicContact CB-CE 4.2Å; E52-M104 HydrophobicContact CG-CE 3.29Å
53W97.7Very high98.3Very high60 Ų6026.9 Ų26.923%0.22714%0.138CC..Hα-helixtrans-63-38.3178.1175.181.4000112.4S49 Y50 F51 R458 L465 K469S49-W53 WeakPolarHBondContact O-CB 3.47Å; S49-W53 PolarHBondContact O-N 3.3Å; Y50-W53 HydrophobicContact CD2-CE3 4.29Å; Y50-W53 HydrophobicContact CE2-CE3 4.31Å; Y50-W53 HydrophobicContact CE2-CZ3 4.34Å; Y50-W53 PolarHBondContact O-N 3.34Å; F51-W53 VanDerWaalsContact C-N 3.35Å; F51-W53 PolarHBondContact O-N 3.18Å; W53-R458 VanDerWaalsContact CD1-NH2 3.26Å; W53-R458 HydrophobicContact CH2-CB 4.48Å; W53-R458 HydrophobicContact CH2-CG 3.97Å; W53-R458 HydrophobicContact CZ2-CG 3.73Å; W53-R458 HydrophobicContact CZ3-CG 4.5Å; W53-L465 HydrophobicContact CH2-CD2 4.06Å; W53-L465 HydrophobicContact CH2-CG 3.97Å; W53-L465 HydrophobicContact CZ3-CD1 4.13Å; W53-L465 HydrophobicContact CZ3-CD2 3.86Å; W53-L465 HydrophobicContact CZ3-CG 3.81Å; W53-K469 HydrophobicContact CD2-CD 4.02Å; W53-K469 HydrophobicContact CE3-CD 4.17Å; W53-K469 HydrophobicContact CH2-CB 4.5Å; W53-K469 HydrophobicContact CH2-CD 3.59Å; W53-K469 HydrophobicContact CZ2-CD 3.39Å; W53-K469 HydrophobicContact CZ3-CD 3.98Å; W53-K469 WeakPolarHBondContact O-CE 3.44Å
54L97.6Very high98.3Very high4 Ų426.9 Ų26.92%0.02114%0.138CC..Hα-helixtrans-70.2-32.3174.5-82-178.8000113.1Y50 F51 E52 V56 L465 F468 K469 L472Y50-L54 HydrophobicContact CD1-CD1 4.27Å; Y50-L54 HydrophobicContact CE1-CD1 3.6Å; Y50-L54 HydrophobicContact CE2-CD1 3.92Å; Y50-L54 HydrophobicContact CE2-CG 4.06Å; Y50-L54 VanDerWaalsContact CZ-CD1 3.41Å; Y50-L54 PolarHBondContact O-N 3.07Å; F51-L54 PolarHBondContact O-N 3.49Å; E52-L54 VanDerWaalsContact C-N 3.32Å; E52-L54 PolarHBondContact O-N 2.82Å; L54-V56 HydrophobicContact CB-CG2 4.01Å; L54-V56 HydrophobicContact CD1-CG2 4.32Å; L54-L465 HydrophobicContact CD2-CD1 3.77Å; L54-F468 HydrophobicContact CD2-CD1 4.26Å; L54-K469 HydrophobicContact CD2-CB 4.12Å; L54-L472 HydrophobicContact CB-CD1 4.27Å; L54-L472 WeakPolarHBondContact O-CD1 3.2Å
55G96.9Very high98.3Very high40 Ų4026.9 Ų26.941%0.41214%0.138SC..THydrogen-bonded Turntrans90.319-169.700000113.9F51 E52F51-G55 PolarHBondContact O-N 3.21Å; E52-G55 PolarHBondContact O-N 3.45Å
56V98.1Very high98.3Very high1 Ų125.5 Ų25.51%0.00614%0.136CC..  trans-80.9133.8173.9174.30000109.2I21 Y23 F51 L54 L59 L472I21-V56 HydrophobicContact CD1-CG2 3.86Å; I21-V56 HydrophobicContact CG1-CG1 4.34Å; I21-V56 HydrophobicContact CG1-CG2 3.98Å; Y23-V56 HydrophobicContact CD2-CG2 4.34Å; Y23-V56 HydrophobicContact CG-CG1 4.43Å; F51-V56 HydrophobicContact CB-CB 4.15Å; F51-V56 HydrophobicContact CD1-CB 4.18Å; F51-V56 HydrophobicContact CD1-CG1 4.17Å; F51-V56 PolarHBondContact O-N 2.6Å; L54-V56 HydrophobicContact CB-CG2 4.01Å; L54-V56 HydrophobicContact CD1-CG2 4.32Å; V56-L59 HydrophobicContact CG1-CD2 3.91Å; V56-L472 HydrophobicContact CG2-CD1 4.05Å
57K97.9Very high98.4Very high82 Ų8221 Ų2136%0.35712%0.116SC..  trans-124.4-4.9180-56.3-178.8-178175.70114.3T20 M104 F105T20-K57 HydrophobicContact CG2-CB 4.03Å; T20-K57 WeakPolarHBondContact OG1-CB 3.38Å; T20-K57 PolarHBondContact OG1-N 3.04Å; K57-M104 CarbonylContact O-C 3.58Å; K57-M104 WeakPolarHBondContact O-CA 3.49Å; K57-M104 WeakPolarHBondContact O-CB 3.38Å; K57-F105 WeakPolarHBondContact O-CD2 3.33Å; K57-F105 PolarHBondContact O-N 3.01Å
58A98.6Very high98.3Very high0 Ų022.2 Ų22.20%013%0.127CC..EExtended strand (participates in β ladder)trans-130.2129.7174.700000110.2W16 T20 I22 Y23 F105W16-A58 HydrophobicContact CE3-CB 4.09Å; W16-A58 HydrophobicContact CH2-CB 4.41Å; W16-A58 HydrophobicContact CZ3-CB 3.56Å; T20-A58 HydrophobicContact CG2-CB 3.86Å; I22-A58 HydrophobicContact CG1-CB 4.18Å; Y23-A58 PolarHBondContact N-O 3.03Å; A58-F105 WeakPolarHBondContact CA-O 3.41Å; A58-F105 HydrophobicContact CB-CB 4.42Å
59L98.9Very high98.3Very high0 Ų023.6 Ų23.60%013%0.134CC..EExtended strand (participates in β ladder)trans-111.8131.4176.1-51.8-177.9000108.5Y23 I25 I44 L48 F51 V56 M99 F105 L106 V107Y23-L59 WeakPolarHBondContact O-CA 3.41Å; I25-L59 HydrophobicContact CD1-CB 4.25Å; I25-L59 HydrophobicContact CD1-CD1 3.96Å; I25-L59 HydrophobicContact CD1-CD2 4.23Å; I25-L59 HydrophobicContact CD1-CG 4.37Å; I44-L59 HydrophobicContact CG2-CD1 4.08Å; L48-L59 HydrophobicContact CD2-CD1 4.27Å; F51-L59 HydrophobicContact CD1-CD2 3.8Å; F51-L59 HydrophobicContact CD2-CD1 3.86Å; F51-L59 HydrophobicContact CD2-CD2 3.93Å; F51-L59 HydrophobicContact CE1-CD2 3.77Å; F51-L59 HydrophobicContact CE2-CD1 3.67Å; F51-L59 HydrophobicContact CE2-CD2 3.91Å; F51-L59 HydrophobicContact CE2-CG 4.47Å; F51-L59 HydrophobicContact CG-CD2 3.89Å; F51-L59 HydrophobicContact CZ-CD1 4.26Å; F51-L59 HydrophobicContact CZ-CD2 3.82Å; V56-L59 HydrophobicContact CG1-CD2 3.91Å; L59-M99 HydrophobicContact CB-CE 3.88Å; L59-M99 HydrophobicContact CD1-CE 3.63Å; L59-M99 HydrophobicContact CD1-SD 3.94Å; L59-M99 HydrophobicContact CG-CE 3.64Å; L59-F105 PolarHBondContact N-O 3.48Å; L59-L106 HydrophobicContact CB-CD1 4.22Å; L59-V107 PolarHBondContact O-N 2.89Å
60W98.8Very high98.2Very high5 Ų522.8 Ų22.82%0.01913%0.126CC..EExtended strand (participates in β ladder)trans-105.9117.9165.7162.827.9000107.7I22 Y23 Q24 I25 V107 D109 R212 M285 L307 I377I22-W60 HydrophobicContact CG2-CB 3.51Å; Y23-W60 PolarHBondContact O-N 3.42Å; Q24-W60 CarbonylContact C-O 3.21Å; Q24-W60 VanDerWaalsContact CA-O 3.28Å; Q24-W60 WeakPolarHBondContact CA-O 3.44Å; Q24-W60 HydrophobicContact CB-CD2 4.21Å; Q24-W60 HydrophobicContact CB-CE3 3.68Å; Q24-W60 HydrophobicContact CB-CZ3 4.2Å; Q24-W60 VanDerWaalsContact CD-CZ3 3.41Å; Q24-W60 HydrophobicContact CG-CD2 3.88Å; Q24-W60 HydrophobicContact CG-CE3 3.65Å; Q24-W60 HydrophobicContact CG-CG 4.47Å; Q24-W60 HydrophobicContact CG-CH2 4.42Å; Q24-W60 HydrophobicContact CG-CZ3 3.96Å; Q24-W60 VanDerWaalsContact NE2-CZ3 3.29Å; I25-W60 PolarHBondContact N-O 2.93Å; W60-V107 WeakPolarHBondContact CA-O 3.31Å; W60-V107 HydrophobicContact CB-CB 4.19Å; W60-V107 HydrophobicContact CB-CG1 4.37Å; W60-V107 HydrophobicContact CG-CG1 4.46Å; W60-D109 WeakPolarHBondContact CZ2-OD2 3.29Å; W60-D109 PolarHBondContact NE1-OD2 2.75Å; W60-R212 HydrophobicContact CD2-CB 4.34Å; W60-R212 HydrophobicContact CH2-CG 3.92Å; W60-R212 HydrophobicContact CZ2-CB 4.01Å; W60-R212 VanDerWaalsContact CZ2-CD 3.4Å; W60-R212 HydrophobicContact CZ2-CG 3.48Å; W60-R212 VanDerWaalsContact CZ2-CG 3.48Å; W60-M285 HydrophobicContact CB-CE 4.34Å; W60-M285 HydrophobicContact CD2-CE 3.48Å; W60-M285 VanDerWaalsContact CD2-CE 3.48Å; W60-M285 HydrophobicContact CE3-CE 3.36Å; W60-M285 HydrophobicContact CG-CE 3.91Å; W60-M285 HydrophobicContact CH2-CE 4.38Å; W60-M285 HydrophobicContact CZ3-CE 3.83Å; W60-L307 HydrophobicContact CH2-CD1 4.27Å; W60-L307 HydrophobicContact CZ3-CD1 4.42Å; W60-I377 HydrophobicContact CE3-CG2 4.18Å; W60-I377 HydrophobicContact CZ3-CG2 4.13Å
61I98.8Very high98.1Very high1 Ų122.8 Ų22.81%0.00513%0.126CC..EExtended strand (participates in β ladder)trans-100.1130.3176.261.9174.2000109.6I25 P27 L41 I44 V64 L92 L106 V107 D109I25-I61 HydrophobicContact CB-CG2 4.24Å; I25-I61 HydrophobicContact CD1-CG2 4.43Å; P27-I61 HydrophobicContact CG-CB 4.35Å; L41-I61 HydrophobicContact CD2-CD1 4.23Å; I44-I61 HydrophobicContact CD1-CG2 3.81Å; I61-V64 HydrophobicContact CD1-CG1 4.41Å; I61-V64 HydrophobicContact CD1-CG2 4.16Å; I61-L92 HydrophobicContact CD1-CD1 4.03Å; I61-L106 HydrophobicContact CD1-CD1 4.13Å; I61-L106 HydrophobicContact CD1-CD2 4.26Å; I61-L106 HydrophobicContact CG1-CD1 4.11Å; I61-L106 HydrophobicContact CG2-CD1 3.91Å; I61-V107 PolarHBondContact N-O 2.93Å; I61-D109 WeakPolarHBondContact O-CB 3.11Å; I61-D109 PolarHBondContact O-N 3.01Å
62S98.6Very high98Very high2 Ų223.5 Ų23.51%0.01413%0.13CC..PPolyproline II helixtrans-57.2165.2165.8-71.20000110.9I25 V64I25-S62 PolarHBondContact O-N 2.68Å; S62-V64 PolarHBondContact O-N 3.36Å
63P98.6Very high98Very high4 Ų418.8 Ų18.83%0.02611%0.108CC..PPolyproline II helixtrans-52.5134-170.8-3037.3000114Y65 G73 Y74 D109 V111P63-Y65 HydrophobicContact CB-CD2 4Å; P63-Y65 HydrophobicContact CB-CE2 4.33Å; P63-G73 VanDerWaalsContact CB-O 3.27Å; P63-G73 WeakPolarHBondContact CB-O 3.12Å; P63-Y74 VanDerWaalsContact CD-OH 3.28Å; P63-Y74 WeakPolarHBondContact CD-OH 3.23Å; P63-Y74 HydrophobicContact CG-CD1 3.98Å; P63-Y74 HydrophobicContact CG-CD2 4.26Å; P63-Y74 HydrophobicContact CG-CE1 3.71Å; P63-Y74 HydrophobicContact CG-CE2 4.03Å; P63-Y74 HydrophobicContact CG-CG 4.21Å; P63-D109 HydrophobicContact CG-CB 4Å; P63-V111 HydrophobicContact CG-CG2 4.24Å
64V98.7Very high98Very high0 Ų016.3 Ų16.30%010%0.098CC..  trans-122.410.9173.5-64.60000112.2P27 L41 I61 S62 V82 D83 F86 M108P27-V64 HydrophobicContact CB-CG1 4.03Å; P27-V64 HydrophobicContact CG-CG1 3.66Å; L41-V64 HydrophobicContact CD2-CG1 4.24Å; L41-V64 HydrophobicContact CD2-CG2 4.5Å; I61-V64 HydrophobicContact CD1-CG1 4.41Å; I61-V64 HydrophobicContact CD1-CG2 4.16Å; S62-V64 PolarHBondContact O-N 3.36Å; V64-V82 HydrophobicContact CG2-CG2 4.42Å; V64-V82 CarbonylContact O-C 3.56Å; V64-V82 WeakPolarHBondContact O-CA 3.16Å; V64-D83 PolarHBondContact O-N 3.24Å; V64-F86 HydrophobicContact CB-CB 4.22Å; V64-F86 HydrophobicContact CB-CD2 3.72Å; V64-F86 HydrophobicContact CB-CE2 4.33Å; V64-F86 HydrophobicContact CB-CG 4.09Å; V64-F86 HydrophobicContact CG1-CB 4.29Å; V64-F86 HydrophobicContact CG1-CD1 4.46Å; V64-F86 HydrophobicContact CG1-CD2 3.97Å; V64-F86 HydrophobicContact CG1-CE2 4.4Å; V64-F86 HydrophobicContact CG1-CG 4Å; V64-M108 HydrophobicContact CG2-CE 3.99Å
65Y98.8Very high98Very high0 Ų016.1 Ų16.10%010%0.097CC..EExtended strand (participates in β ladder)trans-70.2156179.4-48.4-69.1000111.6P63 S67 I76 S81 M108 D109 M110 W203P63-Y65 HydrophobicContact CB-CD2 4Å; P63-Y65 HydrophobicContact CB-CE2 4.33Å; Y65-S67 PolarHBondContact O-N 3.44Å; Y65-S67 VanDerWaalsContact O-N 3.16Å; Y65-I76 HydrophobicContact CD2-CD1 3.31Å; Y65-I76 HydrophobicContact CD2-CG1 3.86Å; Y65-I76 HydrophobicContact CE2-CD1 3.77Å; Y65-I76 HydrophobicContact CG-CD1 4.16Å; Y65-I76 HydrophobicContact CG-CG1 4.43Å; Y65-I76 HydrophobicContact CG-CG2 4.33Å; Y65-S81 CarbonylContact C-O 3.56Å; Y65-S81 WeakPolarHBondContact CA-O 3.46Å; Y65-M108 HydrophobicContact CD1-CE 4.3Å; Y65-M108 HydrophobicContact CE1-CE 3.42Å; Y65-M108 VanDerWaalsContact CE1-CE 3.42Å; Y65-D109 WeakPolarHBondContact CE2-O 3.31Å; Y65-D109 PolarHBondContact OH-O 3.29Å; Y65-D109 VanDerWaalsContact OH-O 3.1Å; Y65-M110 WeakPolarHBondContact OH-CE 3.28Å; Y65-W203 AromaticContact CD1-CZ2 3.62Å; Y65-W203 HydrophobicContact CD1-CZ2 3.62Å; Y65-W203 HydrophobicContact CE1-CD2 4.37Å; Y65-W203 AromaticContact CE1-CE2 3.48Å; Y65-W203 VanDerWaalsContact CE1-CE2 3.48Å; Y65-W203 AromaticContact CE1-CZ2 3.57Å; Y65-W203 HydrophobicContact CE1-CZ2 3.57Å; Y65-W203 AromaticContact CE1-NE1 3.38Å
66C98.8Very high98.1Very high24 Ų2414.2 Ų14.216%0.1628%0.078CC..EExtended strand (participates in β ladder)trans-49.5120.4170.6-79.30000111.4S77 D78 S81 D83C66-S77 PolarHBondContact O-N 2.83Å; C66-S77 PolarHBondContact O-OG 2.83Å; C66-D78 HydrophobicContact CB-CB 3.86Å; C66-D78 PolarHBondContact O-N 3.19Å; C66-S81 PolarHBondContact N-O 3.19Å; C66-D83 WeakPolarHBondContact CA-OD2 3.37Å
67S98.6Very high98.2Very high9 Ų915.4 Ų15.46%0.0639%0.086CC..  trans-149.4144.7-174.7170.60000110.4Y65 M69 D75 D83Y65-S67 PolarHBondContact O-N 3.44Å; Y65-S67 VanDerWaalsContact O-N 3.16Å; S67-M69 WeakPolarHBondContact O-CG 3.31Å; S67-M69 PolarHBondContact O-N 2.95Å; S67-M69 VanDerWaalsContact O-N 3.13Å; S67-M69 PolarHBondContact OG-N 3.11Å; S67-D75 VanDerWaalsContact CB-O 3.25Å; S67-D75 WeakPolarHBondContact CB-O 3.35Å; S67-D75 VanDerWaalsContact OG-CG 3.22Å; S67-D75 PolarHBondContact OG-O 3.03Å; S67-D75 PolarHBondContact OG-OD1 2.91Å; S67-D75 VanDerWaalsContact OG-OD1 3.07Å; S67-D75 PolarHBondContact OG-OD2 3.29Å; S67-D83 PolarHBondContact N-OD2 3.15Å
68P98.1Very high98.2Very high60 Ų6014 Ų1439%0.398%0.082SC..  trans-62.9-9.8167.2-2336.2000113.7V70 D75 S116 K118P68-V70 VanDerWaalsContact C-N 3.34Å; P68-V70 HydrophobicContact CB-CG2 4.24Å; P68-D75 VanDerWaalsContact CD-O 3.32Å; P68-D75 WeakPolarHBondContact CD-O 3.47Å; P68-D75 WeakPolarHBondContact CD-OD2 3.47Å; P68-S116 WeakPolarHBondContact CG-OG 3.2Å; P68-K118 HydrophobicContact CG-CB 3.95Å; P68-K118 HydrophobicContact CG-CG 3.82Å
69M97Very high98.2Very high31 Ų3114 Ų1415%0.1538%0.082CC..  trans67.727.9176.5-59-66164.300114.2R28 S67 D71 F72 D75 D83 L85 F86R28-M69 VanDerWaalsContact NH2-CB 3.32Å; R28-M69 PolarHBondContact NH2-SD 3.48Å; S67-M69 WeakPolarHBondContact O-CG 3.31Å; S67-M69 PolarHBondContact O-N 2.95Å; S67-M69 VanDerWaalsContact O-N 3.13Å; S67-M69 PolarHBondContact OG-N 3.11Å; M69-D71 VanDerWaalsContact C-N 3.33Å; M69-F72 PolarHBondContact O-N 2.96Å; M69-D75 PolarHBondContact N-OD2 2.88Å; M69-D83 HydrophobicContact CE-CB 3.75Å; M69-D83 VanDerWaalsContact CE-OD2 3.29Å; M69-D83 WeakPolarHBondContact CE-OD2 3.46Å; M69-L85 HydrophobicContact CE-CD2 4.31Å; M69-L85 HydrophobicContact CG-CD2 4.42Å; M69-L85 HydrophobicContact SD-CD2 4.42Å; M69-F86 HydrophobicContact CE-CD2 4.41Å; M69-F86 HydrophobicContact CE-CE2 3.61Å; M69-F86 HydrophobicContact CE-CZ 4.27Å; M69-F86 HydrophobicContact SD-CE2 4.41Å
70V96.7Very high98.2Very high52 Ų5217.6 Ų17.632%0.31510%0.096SC..THydrogen-bonded Turntrans-65.6-40.5174.8-177.30000110.5P68 D75 L179 E181 P399P68-V70 VanDerWaalsContact C-N 3.34Å; P68-V70 HydrophobicContact CB-CG2 4.24Å; V70-D75 WeakPolarHBondContact CB-OD2 3.39Å; V70-D75 PolarHBondContact N-OD1 2.69Å; V70-D75 PolarHBondContact N-OD2 2.83Å; V70-L179 HydrophobicContact CG1-CD1 3.84Å; V70-E181 HydrophobicContact CG1-CB 4.28Å; V70-E181 HydrophobicContact CG1-CG 4.24Å; V70-E181 HydrophobicContact CG2-CB 4.48Å; V70-E181 HydrophobicContact CG2-CG 4.38Å; V70-P399 WeakPolarHBondContact O-CG 3.4Å
71D96.6Very high98.2Very high5 Ų519.2 Ų19.23%0.02711%0.108CC..THydrogen-bonded Turntrans-117.942.9171.4-164.510.6000110.7M69 G73 Y74 D75 L179 Q182 R416M69-D71 VanDerWaalsContact C-N 3.33Å; D71-G73 PolarHBondContact O-N 3.46Å; D71-Y74 WeakPolarHBondContact O-CD2 3.47Å; D71-Y74 PolarHBondContact O-N 3.44Å; D71-D75 PolarHBondContact N-OD1 3.39Å; D71-L179 HydrophobicContact CB-CD1 3.89Å; D71-Q182 PolarHBondContact OD2-NE2 3.49Å; D71-Q182 VanDerWaalsContact OD2-NE2 3.15Å; D71-R416 IonicContact OD1-CZ 3.75Å; D71-R416 IonicContact OD1-NH1 2.69Å; D71-R416 IonicContact OD1-NH2 2.89Å; D71-R416 PolarHBondContact OD1-NH2 2.63Å; D71-R416 IonicContact OD2-NH1 2.65Å; D71-R416 IonicContact OD2-NH2 3.86Å
72F96.7Very high98.2Very high15 Ų1519.5 Ų19.57%0.06611%0.11CC..THydrogen-bonded Turntrans51.730.5171.6-50.6-45.7000115.9Y26 M69 K397 D398 R420 W442Y26-F72 VanDerWaalsContact OH-CB 3.29Å; Y26-F72 WeakPolarHBondContact OH-CB 3.39Å; Y26-F72 WeakPolarHBondContact OH-CD2 3.45Å; M69-F72 PolarHBondContact O-N 2.96Å; F72-K397 HydrophobicContact CE1-CB 4.12Å; F72-K397 HydrophobicContact CZ-CB 3.74Å; F72-K397 WeakPolarHBondContact CZ-O 3.34Å; F72-D398 HydrophobicContact CE2-CB 4.24Å; F72-R420 VanDerWaalsContact CD2-NH1 3.33Å; F72-W442 HydrophobicContact CD1-CZ3 4.25Å; F72-W442 AromaticContact CE1-CZ3 3.88Å; F72-W442 HydrophobicContact CE1-CZ3 3.88Å; F72-W442 HydrophobicContact CE2-CH2 4.39Å; F72-W442 HydrophobicContact CE2-CZ3 4.31Å; F72-W442 HydrophobicContact CZ-CH2 4.41Å; F72-W442 AromaticContact CZ-CZ3 3.89Å; F72-W442 HydrophobicContact CZ-CZ3 3.89Å
73G97.4Very high98.2Very high0 Ų020.5 Ų20.50%012%0.115CC..THydrogen-bonded Turntrans115.6-11.8177.800000114.4P63 D71 D75 I76P63-G73 VanDerWaalsContact CB-O 3.27Å; P63-G73 WeakPolarHBondContact CB-O 3.12Å; D71-G73 PolarHBondContact O-N 3.46Å; G73-D75 VanDerWaalsContact C-N 3.35Å; G73-I76 VanDerWaalsContact O-CG1 3.31Å; G73-I76 WeakPolarHBondContact O-CG1 3.09Å
74Y98.1Very high98.2Very high8 Ų825.5 Ų25.53%0.03115%0.147CC..SBendtrans-78-20174.8-73.3-88.4000112.5P63 D71 I76 D109 V111 H114 D214 H347P63-Y74 VanDerWaalsContact CD-OH 3.28Å; P63-Y74 WeakPolarHBondContact CD-OH 3.23Å; P63-Y74 HydrophobicContact CG-CD1 3.98Å; P63-Y74 HydrophobicContact CG-CD2 4.26Å; P63-Y74 HydrophobicContact CG-CE1 3.71Å; P63-Y74 HydrophobicContact CG-CE2 4.03Å; P63-Y74 HydrophobicContact CG-CG 4.21Å; D71-Y74 WeakPolarHBondContact O-CD2 3.47Å; D71-Y74 PolarHBondContact O-N 3.44Å; Y74-I76 PolarHBondContact O-N 2.82Å; Y74-D109 PolarHBondContact OH-OD2 3.43Å; Y74-V111 HydrophobicContact CD1-CG2 3.64Å; Y74-V111 HydrophobicContact CE1-CG2 4.11Å; Y74-H114 PolarHBondContact O-NE2 3.22Å; Y74-D214 WeakPolarHBondContact CE1-OD1 3.21Å; Y74-H347 AromaticContact CE2-NE2 3.94Å; Y74-H347 AromaticContact CZ-NE2 3.52Å; Y74-H347 PolarHBondContact OH-CE1 3.24Å; Y74-H347 VanDerWaalsContact OH-CE1 3.3Å; Y74-H347 PolarHBondContact OH-NE2 2.91Å
75D98.4Very high98.1Very high0 Ų027.3 Ų27.30%016%0.157CC..SBendtrans-8676.7167.158.1-55.8000111S67 P68 M69 V70 D71 G73 S116 Q182S67-D75 VanDerWaalsContact CB-O 3.25Å; S67-D75 WeakPolarHBondContact CB-O 3.35Å; S67-D75 VanDerWaalsContact OG-CG 3.22Å; S67-D75 PolarHBondContact OG-O 3.03Å; S67-D75 PolarHBondContact OG-OD1 2.91Å; S67-D75 VanDerWaalsContact OG-OD1 3.07Å; S67-D75 PolarHBondContact OG-OD2 3.29Å; P68-D75 VanDerWaalsContact CD-O 3.32Å; P68-D75 WeakPolarHBondContact CD-O 3.47Å; P68-D75 WeakPolarHBondContact CD-OD2 3.47Å; M69-D75 PolarHBondContact N-OD2 2.88Å; V70-D75 WeakPolarHBondContact CB-OD2 3.39Å; V70-D75 PolarHBondContact N-OD1 2.69Å; V70-D75 PolarHBondContact N-OD2 2.83Å; D71-D75 PolarHBondContact N-OD1 3.39Å; G73-D75 VanDerWaalsContact C-N 3.35Å; D75-S116 WeakPolarHBondContact O-CB 3.28Å; D75-Q182 HydrophobicContact CB-CG 4.03Å
76I98.8Very high98.1Very high0 Ų027.4 Ų27.40%016%0.157CC..  trans-76.4125.6-172.8-59169.1000111.6Y65 G73 Y74 Y79 V111 T115 S116 H119Y65-I76 HydrophobicContact CD2-CD1 3.31Å; Y65-I76 HydrophobicContact CD2-CG1 3.86Å; Y65-I76 HydrophobicContact CE2-CD1 3.77Å; Y65-I76 HydrophobicContact CG-CD1 4.16Å; Y65-I76 HydrophobicContact CG-CG1 4.43Å; Y65-I76 HydrophobicContact CG-CG2 4.33Å; G73-I76 VanDerWaalsContact O-CG1 3.31Å; G73-I76 WeakPolarHBondContact O-CG1 3.09Å; Y74-I76 PolarHBondContact O-N 2.82Å; I76-Y79 HydrophobicContact CB-CE1 4.17Å; I76-Y79 HydrophobicContact CB-CE2 4.17Å; I76-Y79 HydrophobicContact CD1-CD1 3.95Å; I76-Y79 HydrophobicContact CD1-CE1 3.31Å; I76-Y79 HydrophobicContact CG1-CE1 4.33Å; I76-Y79 HydrophobicContact CG2-CD1 3.89Å; I76-Y79 HydrophobicContact CG2-CD2 3.83Å; I76-Y79 HydrophobicContact CG2-CE1 3.94Å; I76-Y79 HydrophobicContact CG2-CE2 3.86Å; I76-Y79 HydrophobicContact CG2-CG 3.81Å; I76-V111 HydrophobicContact CD1-CB 3.84Å; I76-V111 HydrophobicContact CD1-CG2 3.9Å; I76-T115 WeakPolarHBondContact O-CB 3.4Å; I76-S116 WeakPolarHBondContact O-CB 3.4Å; I76-S116 PolarHBondContact O-N 2.86Å; I76-H119 PolarHBondContact O-CD2 2.95Å
77S98.7Very high98.1Very high25 Ų2527 Ų2718%0.17516%0.157CC..SBendtrans-103.7-21.8177.461.90000114.5C66 H119 P120C66-S77 PolarHBondContact O-N 2.83Å; C66-S77 PolarHBondContact O-OG 2.83Å; S77-H119 VanDerWaalsContact C-CD2 3.42Å; S77-H119 PolarHBondContact O-CD2 3.04Å; S77-P120 WeakPolarHBondContact O-CD 3.45Å
78D98.7Very high98.1Very high52 Ų5229.4 Ų29.428%0.27817%0.171SC..EExtended strand (participates in β ladder)trans-147.3114.9166.1171.124000110.8C66 R80 S81C66-D78 HydrophobicContact CB-CB 3.86Å; C66-D78 PolarHBondContact O-N 3.19Å; D78-R80 VanDerWaalsContact C-N 3.29Å; D78-R80 PolarHBondContact O-N 2.92Å; D78-R80 PolarHBondContact OD1-N 3.16Å; D78-S81 WeakPolarHBondContact OD2-CB 3.47Å; D78-S81 PolarHBondContact OD2-OG 2.82Å
79Y98.7Very high98.2Very high0 Ų028.2 Ų28.20%016%0.162CC..EExtended strand (participates in β ladder)trans-72-13.5179.9-80.8-82.9000115.3I76 M110 V111 H114 T115 H119 M196 I199 W203I76-Y79 HydrophobicContact CB-CE1 4.17Å; I76-Y79 HydrophobicContact CB-CE2 4.17Å; I76-Y79 HydrophobicContact CD1-CD1 3.95Å; I76-Y79 HydrophobicContact CD1-CE1 3.31Å; I76-Y79 HydrophobicContact CG1-CE1 4.33Å; I76-Y79 HydrophobicContact CG2-CD1 3.89Å; I76-Y79 HydrophobicContact CG2-CD2 3.83Å; I76-Y79 HydrophobicContact CG2-CE1 3.94Å; I76-Y79 HydrophobicContact CG2-CE2 3.86Å; I76-Y79 HydrophobicContact CG2-CG 3.81Å; Y79-M110 HydrophobicContact CD1-SD 3.84Å; Y79-M110 HydrophobicContact CE1-SD 3.83Å; Y79-V111 PolarHBondContact OH-O 2.9Å; Y79-H114 PolarHBondContact OH-O 3.16Å; Y79-T115 HydrophobicContact CE2-CG2 3.82Å; Y79-H119 AromaticContact CD2-NE2 3.86Å; Y79-M196 HydrophobicContact CE1-CE 4.39Å; Y79-M196 HydrophobicContact CE2-CE 4.46Å; Y79-I199 HydrophobicContact CD1-CD1 4.23Å; Y79-I199 HydrophobicContact CD1-CG2 3.83Å; Y79-I199 HydrophobicContact CD2-CD1 3.71Å; Y79-I199 HydrophobicContact CG-CD1 3.55Å; Y79-I199 HydrophobicContact CG-CG1 4.21Å; Y79-I199 HydrophobicContact CG-CG2 4.01Å; Y79-W203 VanDerWaalsContact O-CE2 3.23Å; Y79-W203 WeakPolarHBondContact O-CZ2 3.28Å; Y79-W203 PolarHBondContact O-NE1 3.41Å
80R98.6Very high98.2Very high77 Ų7733.1 Ų33.129%0.29118%0.184SC..EExtended strand (participates in β ladder)trans-104.71.4-171.5-64.9178.7177.686.1-7.3113.2D78 N89 E195 H202D78-R80 VanDerWaalsContact C-N 3.29Å; D78-R80 PolarHBondContact O-N 2.92Å; D78-R80 PolarHBondContact OD1-N 3.16Å; R80-N89 PolarHBondContact O-ND2 3Å; R80-E195 IonicContact CZ-OE2 3.9Å; R80-E195 IonicContact NH2-OE2 3.78Å; R80-E195 PolarHBondContact NH2-OE2 2.83Å; R80-H202 PolarHBondContact O-NE2 3.38Å
81S98.7Very high98.3Very high39 Ų3932.2 Ų32.227%0.27318%0.178SC..EExtended strand (participates in β ladder)trans-131.9136.6-178.4-53.10000110.7Y65 C66 D78 N89Y65-S81 CarbonylContact C-O 3.56Å; Y65-S81 WeakPolarHBondContact CA-O 3.46Å; C66-S81 PolarHBondContact N-O 3.19Å; D78-S81 WeakPolarHBondContact OD2-CB 3.47Å; D78-S81 PolarHBondContact OD2-OG 2.82Å; S81-N89 WeakPolarHBondContact CA-OD1 3.28Å
82V98.8Very high98.4Very high7 Ų732 Ų324%0.04218%0.176CC..EExtended strand (participates in β ladder)trans-66.1136.5163.7172.30000108.9L41 V64 F86 N89 L92 W203L41-V82 HydrophobicContact CD1-CG1 3.71Å; L41-V82 HydrophobicContact CD1-CG2 4.2Å; V64-V82 HydrophobicContact CG2-CG2 4.42Å; V64-V82 CarbonylContact O-C 3.56Å; V64-V82 WeakPolarHBondContact O-CA 3.16Å; V82-F86 HydrophobicContact CG1-CB 4.11Å; V82-N89 WeakPolarHBondContact CG2-OD1 3.15Å; V82-N89 PolarHBondContact N-OD1 3.08Å; V82-L92 HydrophobicContact CG2-CB 3.99Å; V82-L92 HydrophobicContact CG2-CD2 4.02Å; V82-W203 HydrophobicContact CG2-CH2 4.1Å; V82-W203 HydrophobicContact CG2-CZ3 4.45Å
83D98.7Very high98.5Very high22 Ų2235.1 Ų35.112%0.11819%0.19CC..  trans-64.1135175.2-162.8-77.6000110.7V64 C66 S67 M69 L85 F86 G87V64-D83 PolarHBondContact O-N 3.24Å; C66-D83 WeakPolarHBondContact CA-OD2 3.37Å; S67-D83 PolarHBondContact N-OD2 3.15Å; M69-D83 HydrophobicContact CE-CB 3.75Å; M69-D83 VanDerWaalsContact CE-OD2 3.29Å; M69-D83 WeakPolarHBondContact CE-OD2 3.46Å; D83-L85 PolarHBondContact O-N 2.91Å; D83-L85 WeakPolarHBondContact OD1-CB 3.46Å; D83-L85 PolarHBondContact OD1-N 3.47Å; D83-F86 HydrophobicContact CB-CD2 3.81Å; D83-F86 HydrophobicContact CB-CE2 4.3Å; D83-F86 PolarHBondContact O-N 3.16Å; D83-G87 PolarHBondContact O-N 2.96Å
84P98.4Very high98.6Very high110 Ų11038.7 Ų38.771%0.71421%0.209SC*.THydrogen-bonded Turntrans-53.9-22.9176.5-2835.8000114.7F86P84-F86 PolarHBondContact O-N 3Å
85L98Very high98.6Very high38 Ų3838.3 Ų38.320%0.19921%0.207CC..THydrogen-bonded Turntrans-61.7-30.5172.8-175.163.7000113I38 M69 D83I38-L85 HydrophobicContact CB-CD1 4.11Å; I38-L85 HydrophobicContact CD1-CD1 3.74Å; I38-L85 HydrophobicContact CD1-CD2 4.1Å; I38-L85 HydrophobicContact CD1-CG 4.42Å; I38-L85 HydrophobicContact CG1-CD1 4.49Å; I38-L85 HydrophobicContact CG2-CD1 4.11Å; I38-L85 HydrophobicContact CG2-CD2 4Å; I38-L85 HydrophobicContact CG2-CG 3.96Å; M69-L85 HydrophobicContact CE-CD2 4.31Å; M69-L85 HydrophobicContact CG-CD2 4.42Å; M69-L85 HydrophobicContact SD-CD2 4.42Å; D83-L85 PolarHBondContact O-N 2.91Å; D83-L85 WeakPolarHBondContact OD1-CB 3.46Å; D83-L85 PolarHBondContact OD1-N 3.47Å
86F98.7Very high98.7Very high2 Ų238.3 Ų38.31%0.00921%0.207CC..THydrogen-bonded Turntrans-105-16.1-177.2-57.3-59.5000113.9P27 R28 I38 G39 L41 V64 M69 V82 D83 P84P27-F86 HydrophobicContact CB-CD1 4.16Å; P27-F86 HydrophobicContact CB-CE1 4.03Å; R28-F86 HydrophobicContact CG-CE1 3.65Å; R28-F86 HydrophobicContact CG-CZ 3.78Å; I38-F86 HydrophobicContact CG2-CE1 4.32Å; G39-F86 VanDerWaalsContact O-CD1 3.26Å; G39-F86 WeakPolarHBondContact O-CD1 3.29Å; L41-F86 WeakPolarHBondContact CB-O 3.4Å; L41-F86 HydrophobicContact CG-CB 4.34Å; L41-F86 WeakPolarHBondContact CG-O 3.42Å; L41-F86 PolarHBondContact N-O 3.3Å; V64-F86 HydrophobicContact CB-CB 4.22Å; V64-F86 HydrophobicContact CB-CD2 3.72Å; V64-F86 HydrophobicContact CB-CE2 4.33Å; V64-F86 HydrophobicContact CB-CG 4.09Å; V64-F86 HydrophobicContact CG1-CB 4.29Å; V64-F86 HydrophobicContact CG1-CD1 4.46Å; V64-F86 HydrophobicContact CG1-CD2 3.97Å; V64-F86 HydrophobicContact CG1-CE2 4.4Å; V64-F86 HydrophobicContact CG1-CG 4Å; M69-F86 HydrophobicContact CE-CD2 4.41Å; M69-F86 HydrophobicContact CE-CE2 3.61Å; M69-F86 HydrophobicContact CE-CZ 4.27Å; M69-F86 HydrophobicContact SD-CE2 4.41Å; V82-F86 HydrophobicContact CG1-CB 4.11Å; D83-F86 HydrophobicContact CB-CD2 3.81Å; D83-F86 HydrophobicContact CB-CE2 4.3Å; D83-F86 PolarHBondContact O-N 3.16Å; P84-F86 PolarHBondContact O-N 3Å
87G98.4Very high98.7Very high15 Ų1541.8 Ų41.816%0.15523%0.226CC..  trans134.7-142.7-179.700000112.1D83 D91D83-G87 PolarHBondContact O-N 2.96Å; G87-D91 WeakPolarHBondContact CA-OD2 3.06Å
88T98.6Very high98.7Very high59 Ų5943.1 Ų43.136%0.36223%0.229SC..  trans-127.2174.6175.578.90000112.6E90 D91 L92T88-E90 VanDerWaalsContact CB-OE2 3.3Å; T88-E90 WeakPolarHBondContact CB-OE2 3.5Å; T88-E90 PolarHBondContact O-N 2.95Å; T88-E90 WeakPolarHBondContact OG1-CB 3.48Å; T88-E90 PolarHBondContact OG1-N 2.94Å; T88-E90 VanDerWaalsContact OG1-N 3.14Å; T88-E90 PolarHBondContact OG1-OE2 3.04Å; T88-D91 PolarHBondContact N-OD2 3.46Å; T88-D91 PolarHBondContact O-N 3.4Å; T88-D91 VanDerWaalsContact O-N 3.15Å; T88-D91 PolarHBondContact OG1-N 2.91Å; T88-L92 PolarHBondContact O-N 3.13Å; T88-L92 VanDerWaalsContact O-N 3.09Å
89N98.7Very high98.7Very high35 Ų3540.6 Ų40.619%0.18722%0.216CC..Hα-helixtrans-59-33.3171.1-75.45000111.7R80 S81 V82 L92 K93R80-N89 PolarHBondContact O-ND2 3Å; S81-N89 WeakPolarHBondContact CA-OD1 3.28Å; V82-N89 WeakPolarHBondContact CG2-OD1 3.15Å; V82-N89 PolarHBondContact N-OD1 3.08Å; N89-L92 PolarHBondContact O-N 3.04Å; N89-K93 WeakPolarHBondContact O-CB 3.4Å; N89-K93 PolarHBondContact O-N 2.81Å
90E98.7Very high98.6Very high134 Ų13444.1 Ų44.163%0.62623%0.232SC*.Hα-helixtrans-67.8-39.5174.7-63.269.7-15200112T88 L92 K93 L94T88-E90 VanDerWaalsContact CB-OE2 3.3Å; T88-E90 WeakPolarHBondContact CB-OE2 3.5Å; T88-E90 PolarHBondContact O-N 2.95Å; T88-E90 WeakPolarHBondContact OG1-CB 3.48Å; T88-E90 PolarHBondContact OG1-N 2.94Å; T88-E90 VanDerWaalsContact OG1-N 3.14Å; T88-E90 PolarHBondContact OG1-OE2 3.04Å; E90-L92 VanDerWaalsContact C-N 3.34Å; E90-K93 PolarHBondContact O-N 3.27Å; E90-L94 WeakPolarHBondContact O-CB 3.18Å; E90-L94 PolarHBondContact O-N 3.04Å
91D98.7Very high98.6Very high33 Ų3344.7 Ų44.718%0.17625%0.253CS..Hα-helixtrans-62.1-42.9173.9-74-49.1000111.5L41 N42 R45 G87 T88 L94 L95L41-D91 HydrophobicContact CB-CB 4.44Å; L41-D91 HydrophobicContact CD1-CB 4.28Å; N42-D91 PolarHBondContact ND2-OD1 3.38Å; N42-D91 PolarHBondContact OD1-OD1 3.14Å; R45-D91 IonicContact NH1-OD1 3.19Å; G87-D91 WeakPolarHBondContact CA-OD2 3.06Å; T88-D91 PolarHBondContact N-OD2 3.46Å; T88-D91 PolarHBondContact O-N 3.4Å; T88-D91 VanDerWaalsContact O-N 3.15Å; T88-D91 PolarHBondContact OG1-N 2.91Å; D91-L94 PolarHBondContact O-N 3.16Å; D91-L95 PolarHBondContact O-N 3.02Å
92L98.8Very high98.6Very high0 Ų047.1 Ų47.10%026%0.256CS..Hα-helixtrans-64.7-44.2175.9-173.667.2000111.3L41 I61 V82 T88 N89 E90 L94 L95 I96 L106 M108 W203 L206L41-L92 HydrophobicContact CD1-CB 3.76Å; L41-L92 HydrophobicContact CD1-CD1 4.08Å; L41-L92 HydrophobicContact CD2-CD1 3.76Å; I61-L92 HydrophobicContact CD1-CD1 4.03Å; V82-L92 HydrophobicContact CG2-CB 3.99Å; V82-L92 HydrophobicContact CG2-CD2 4.02Å; T88-L92 PolarHBondContact O-N 3.13Å; T88-L92 VanDerWaalsContact O-N 3.09Å; N89-L92 PolarHBondContact O-N 3.04Å; E90-L92 VanDerWaalsContact C-N 3.34Å; L92-L94 VanDerWaalsContact C-N 3.3Å; L92-L94 PolarHBondContact O-N 3.02Å; L92-L95 HydrophobicContact CD1-CD2 4.41Å; L92-L95 WeakPolarHBondContact O-CB 3.33Å; L92-L95 PolarHBondContact O-N 3.35Å; L92-I96 HydrophobicContact CG-CD1 4.1Å; L92-I96 WeakPolarHBondContact O-CG1 3.24Å; L92-I96 PolarHBondContact O-N 3.27Å; L92-L106 HydrophobicContact CD1-CD2 3.82Å; L92-M108 HydrophobicContact CD2-CE 4.03Å; L92-M108 HydrophobicContact CD2-SD 4.05Å; L92-W203 HydrophobicContact CD2-CE3 3.81Å; L92-W203 HydrophobicContact CD2-CH2 4.27Å; L92-W203 HydrophobicContact CD2-CZ3 3.42Å; L92-W203 VanDerWaalsContact CD2-CZ3 3.42Å; L92-L206 HydrophobicContact CD2-CD2 4.14Å
93K98.8Very high98.5Very high82 Ų8248.3 Ų48.336%0.35727%0.27SS..Hα-helixtrans-59.2-44.9176.1-167.6-164.7-179.7-45.10111N89 E90 L95 I96 D97 L206N89-K93 WeakPolarHBondContact O-CB 3.4Å; N89-K93 PolarHBondContact O-N 2.81Å; E90-K93 PolarHBondContact O-N 3.27Å; K93-L95 VanDerWaalsContact C-N 3.33Å; K93-L95 PolarHBondContact O-N 3.43Å; K93-I96 PolarHBondContact O-N 3.49Å; K93-D97 IonicContact NZ-OD1 3.93Å; K93-D97 PolarHBondContact NZ-OD1 2.95Å; K93-D97 IonicContact NZ-OD2 2.94Å; K93-D97 PolarHBondContact NZ-OD2 3.47Å; K93-D97 VanDerWaalsContact O-CG 3.29Å; K93-D97 PolarHBondContact O-N 2.81Å; K93-L206 HydrophobicContact CB-CD1 3.98Å; K93-L206 HydrophobicContact CB-CG 4.2Å; K93-L206 HydrophobicContact CD-CD1 4.25Å; K93-L206 HydrophobicContact CG-CD1 3.98Å; K93-L206 HydrophobicContact CG-CG 4.3Å
94L98.7Very high98.5Very high74 Ų7447.4 Ų47.439%0.38727%0.265SS..Hα-helixtrans-63.5-40.2178.4-179.454.6000111.4R45 E90 D91 L92 D97 E98R45-L94 VanDerWaalsContact NH1-CD2 3.31Å; E90-L94 WeakPolarHBondContact O-CB 3.18Å; E90-L94 PolarHBondContact O-N 3.04Å; D91-L94 PolarHBondContact O-N 3.16Å; L92-L94 VanDerWaalsContact C-N 3.3Å; L92-L94 PolarHBondContact O-N 3.02Å; L94-D97 PolarHBondContact O-N 3.13Å; L94-E98 HydrophobicContact CD1-CG 4.3Å; L94-E98 VanDerWaalsContact O-CB 3.32Å; L94-E98 WeakPolarHBondContact O-CB 3.49Å; L94-E98 WeakPolarHBondContact O-CG 3.48Å; L94-E98 PolarHBondContact O-N 3.26Å
95L98.9Very high98.5Very high0 Ų043.7 Ų43.70%024%0.238CC..Hα-helixtrans-58.4-47.6171.8172.861.8000111.5L41 I44 R45 L48 D91 L92 K93 E98 M99L41-L95 HydrophobicContact CD2-CD2 4.11Å; I44-L95 HydrophobicContact CB-CD2 4.26Å; I44-L95 HydrophobicContact CG2-CD1 4.08Å; I44-L95 HydrophobicContact CG2-CD2 4.05Å; R45-L95 HydrophobicContact CB-CD1 3.98Å; R45-L95 HydrophobicContact CG-CD1 4.39Å; L48-L95 HydrophobicContact CD1-CD1 4.24Å; L48-L95 HydrophobicContact CD2-CD1 4.08Å; L48-L95 HydrophobicContact CG-CD1 4.38Å; D91-L95 PolarHBondContact O-N 3.02Å; L92-L95 HydrophobicContact CD1-CD2 4.41Å; L92-L95 WeakPolarHBondContact O-CB 3.33Å; L92-L95 PolarHBondContact O-N 3.35Å; K93-L95 VanDerWaalsContact C-N 3.33Å; K93-L95 PolarHBondContact O-N 3.43Å; L95-E98 PolarHBondContact O-N 3.04Å; L95-M99 HydrophobicContact CD1-CG 4.04Å; L95-M99 HydrophobicContact CD1-SD 3.81Å; L95-M99 HydrophobicContact CG-CG 4.5Å; L95-M99 HydrophobicContact CG-SD 3.87Å; L95-M99 WeakPolarHBondContact O-CB 3.21Å; L95-M99 VanDerWaalsContact O-CG 3.22Å; L95-M99 WeakPolarHBondContact O-CG 3.43Å; L95-M99 PolarHBondContact O-N 2.91Å
96I98.8Very high98.5Very high0 Ų041.9 Ų41.90%023%0.228CC..Hα-helixtrans-60.8-50.2178.4-68.4164.7000111L92 K93 E98 M99 H100 L106 V208L92-I96 HydrophobicContact CG-CD1 4.1Å; L92-I96 WeakPolarHBondContact O-CG1 3.24Å; L92-I96 PolarHBondContact O-N 3.27Å; K93-I96 PolarHBondContact O-N 3.49Å; I96-E98 VanDerWaalsContact C-N 3.27Å; I96-E98 PolarHBondContact O-N 3.07Å; I96-M99 WeakPolarHBondContact O-CB 3.24Å; I96-M99 PolarHBondContact O-N 3.3Å; I96-M99 VanDerWaalsContact O-N 3.15Å; I96-H100 VanDerWaalsContact CG2-CE1 3.41Å; I96-H100 WeakPolarHBondContact CG2-CE1 3.31Å; I96-H100 WeakPolarHBondContact O-CB 3.49Å; I96-H100 PolarHBondContact O-N 3.06Å; I96-L106 HydrophobicContact CD1-CD2 4.02Å; I96-L106 HydrophobicContact CG1-CB 4.32Å; I96-L106 HydrophobicContact CG1-CD2 3.51Å; I96-V208 HydrophobicContact CD1-CG2 3.85Å
97D98.8Very high98.5Very high73 Ų7341.8 Ų41.839%0.3923%0.228SC..Hα-helixtrans-58.4-42.5-179.3-69.8-17.3000110.9K93 L94 H100 A101K93-D97 IonicContact NZ-OD1 3.93Å; K93-D97 PolarHBondContact NZ-OD1 2.95Å; K93-D97 IonicContact NZ-OD2 2.94Å; K93-D97 PolarHBondContact NZ-OD2 3.47Å; K93-D97 VanDerWaalsContact O-CG 3.29Å; K93-D97 PolarHBondContact O-N 2.81Å; L94-D97 PolarHBondContact O-N 3.13Å; D97-H100 PolarHBondContact O-N 3.45Å; D97-A101 WeakPolarHBondContact O-CB 3.39Å; D97-A101 PolarHBondContact O-N 2.91Å
98E98.8Very high98.6Very high53 Ų5341.1 Ų41.125%0.24822%0.221CC..Hα-helixtrans-68.4-37.6177-85-151.6-138.200113.5R45 L48 L94 L95 I96 R102R45-E98 WeakPolarHBondContact CD-OE1 3.22Å; R45-E98 IonicContact NE-OE1 3.89Å; L48-E98 HydrophobicContact CD1-CB 3.76Å; L94-E98 HydrophobicContact CD1-CG 4.3Å; L94-E98 VanDerWaalsContact O-CB 3.32Å; L94-E98 WeakPolarHBondContact O-CB 3.49Å; L94-E98 WeakPolarHBondContact O-CG 3.48Å; L94-E98 PolarHBondContact O-N 3.26Å; L95-E98 PolarHBondContact O-N 3.04Å; I96-E98 VanDerWaalsContact C-N 3.27Å; I96-E98 PolarHBondContact O-N 3.07Å; E98-R102 VanDerWaalsContact CB-NH1 3.28Å; E98-R102 WeakPolarHBondContact O-CG 3.31Å; E98-R102 PolarHBondContact O-N 3.42Å; E98-R102 PolarHBondContact O-NH1 3.5Å; E98-R102 IonicContact OE2-CZ 3.57Å; E98-R102 IonicContact OE2-NH1 2.65Å; E98-R102 PolarHBondContact OE2-NH1 3Å; E98-R102 IonicContact OE2-NH2 3.35Å; E98-R102 PolarHBondContact OE2-NH2 3.5Å
99M98.7Very high98.6Very high0 Ų038.4 Ų38.40%020%0.204CC..Hα-helixtrans-64-48.2172.7-77.4177.56800110.7L48 L59 L95 I96 A101 R102 G103 M104 F105 L106L48-M99 HydrophobicContact CD1-CG 4.19Å; L48-M99 HydrophobicContact CD2-CG 3.56Å; L48-M99 HydrophobicContact CD2-SD 4.33Å; L59-M99 HydrophobicContact CB-CE 3.88Å; L59-M99 HydrophobicContact CD1-CE 3.63Å; L59-M99 HydrophobicContact CD1-SD 3.94Å; L59-M99 HydrophobicContact CG-CE 3.64Å; L95-M99 HydrophobicContact CD1-CG 4.04Å; L95-M99 HydrophobicContact CD1-SD 3.81Å; L95-M99 HydrophobicContact CG-CG 4.5Å; L95-M99 HydrophobicContact CG-SD 3.87Å; L95-M99 WeakPolarHBondContact O-CB 3.21Å; L95-M99 VanDerWaalsContact O-CG 3.22Å; L95-M99 WeakPolarHBondContact O-CG 3.43Å; L95-M99 PolarHBondContact O-N 2.91Å; I96-M99 WeakPolarHBondContact O-CB 3.24Å; I96-M99 PolarHBondContact O-N 3.3Å; I96-M99 VanDerWaalsContact O-N 3.15Å; M99-A101 VanDerWaalsContact C-N 3.34Å; M99-A101 PolarHBondContact O-N 2.67Å; M99-R102 CarbonylContact O-C 3.56Å; M99-R102 WeakPolarHBondContact O-CA 3.41Å; M99-R102 PolarHBondContact O-N 3.41Å; M99-G103 PolarHBondContact O-N 3.03Å; M99-M104 HydrophobicContact CB-CB 3.9Å; M99-M104 HydrophobicContact CE-CB 4.13Å; M99-M104 HydrophobicContact CG-CB 4.33Å; M99-M104 WeakPolarHBondContact O-CA 3.44Å; M99-M104 WeakPolarHBondContact O-CB 3.2Å; M99-M104 PolarHBondContact O-N 2.99Å; M99-F105 WeakPolarHBondContact CE-O 3.29Å; M99-L106 HydrophobicContact CE-CB 3.89Å; M99-L106 HydrophobicContact CE-CD1 4.14Å; M99-L106 HydrophobicContact SD-CB 4.1Å; M99-L106 HydrophobicContact SD-CD1 4.08Å
100H98.3Very high98.5Very high73 Ų7336.7 Ų36.734%0.33820%0.195SC..Hα-helixtrans-60.9-40.9178.4-71.6-177.7000112.1I96 D97 R102 G103 M104 G207 D209I96-H100 VanDerWaalsContact CG2-CE1 3.41Å; I96-H100 WeakPolarHBondContact CG2-CE1 3.31Å; I96-H100 WeakPolarHBondContact O-CB 3.49Å; I96-H100 PolarHBondContact O-N 3.06Å; D97-H100 PolarHBondContact O-N 3.45Å; H100-R102 PolarHBondContact O-N 3.06Å; H100-R102 VanDerWaalsContact O-N 3.15Å; H100-G103 PolarHBondContact O-N 3.27Å; H100-M104 PolarHBondContact CD2-O 3.01Å; H100-G207 PolarHBondContact CE1-O 3.29Å; H100-G207 PolarHBondContact NE2-O 2.88Å; H100-D209 IonicContact CD2-OD2 3.61Å; H100-D209 IonicContact CE1-OD1 2.71Å; H100-D209 IonicContact CE1-OD2 3.55Å; H100-D209 IonicContact NE2-OD1 2.91Å; H100-D209 PolarHBondContact NE2-OD1 3.27Å; H100-D209 IonicContact NE2-OD2 3.36Å; H100-D209 PolarHBondContact NE2-OD2 3.03Å
101A98.4Very high98.5Very high89 Ų8930.3 Ų30.374%0.73617%0.165SC*.Hα-helixtrans-59.4-24.5174.800000113.3D97 M99D97-A101 WeakPolarHBondContact O-CB 3.39Å; D97-A101 PolarHBondContact O-N 2.91Å; M99-A101 VanDerWaalsContact C-N 3.34Å; M99-A101 PolarHBondContact O-N 2.67Å
102R97.9Very high98.5Very high90 Ų9028.8 Ų28.834%0.3416%0.157SC..THydrogen-bonded Turntrans-98.34.6176.6-64169.9176.787.7-13.2113.1E52 E98 M99 H100 M104E52-R102 WeakPolarHBondContact OE1-CD 3.36Å; E52-R102 WeakPolarHBondContact OE1-CG 3.29Å; E52-R102 IonicContact OE1-NE 3.86Å; E52-R102 IonicContact OE2-NE 3.72Å; E98-R102 VanDerWaalsContact CB-NH1 3.28Å; E98-R102 WeakPolarHBondContact O-CG 3.31Å; E98-R102 PolarHBondContact O-N 3.42Å; E98-R102 PolarHBondContact O-NH1 3.5Å; E98-R102 IonicContact OE2-CZ 3.57Å; E98-R102 IonicContact OE2-NH1 2.65Å; E98-R102 PolarHBondContact OE2-NH1 3Å; E98-R102 IonicContact OE2-NH2 3.35Å; E98-R102 PolarHBondContact OE2-NH2 3.5Å; M99-R102 CarbonylContact O-C 3.56Å; M99-R102 WeakPolarHBondContact O-CA 3.41Å; M99-R102 PolarHBondContact O-N 3.41Å; H100-R102 PolarHBondContact O-N 3.06Å; H100-R102 VanDerWaalsContact O-N 3.15Å; R102-M104 VanDerWaalsContact C-N 3.3Å; R102-M104 HydrophobicContact CB-CE 4.47Å; R102-M104 HydrophobicContact CB-CG 4.12Å; R102-M104 HydrophobicContact CB-SD 4.48Å
103G96.8Very high98.5Very high32 Ų3228.8 Ų28.833%0.3316%0.157SC..THydrogen-bonded Turntrans67.131.1-175.700000113.4M99 H100 F105M99-G103 PolarHBondContact O-N 3.03Å; H100-G103 PolarHBondContact O-N 3.27Å; G103-F105 WeakPolarHBondContact O-CE2 3.27Å
104M98.2Very high98.5Very high4 Ų425 Ų252%0.0214%0.14CC..  trans-102.3165.3173.7-55.3-175172.200111.5L48 F51 E52 K57 M99 H100 R102L48-M104 HydrophobicContact CD2-SD 4.18Å; F51-M104 HydrophobicContact CB-CE 3.86Å; F51-M104 HydrophobicContact CB-SD 4.37Å; E52-M104 HydrophobicContact CB-CE 4.2Å; E52-M104 HydrophobicContact CG-CE 3.29Å; K57-M104 CarbonylContact O-C 3.58Å; K57-M104 WeakPolarHBondContact O-CA 3.49Å; K57-M104 WeakPolarHBondContact O-CB 3.38Å; M99-M104 HydrophobicContact CB-CB 3.9Å; M99-M104 HydrophobicContact CE-CB 4.13Å; M99-M104 HydrophobicContact CG-CB 4.33Å; M99-M104 WeakPolarHBondContact O-CA 3.44Å; M99-M104 WeakPolarHBondContact O-CB 3.2Å; M99-M104 PolarHBondContact O-N 2.99Å; H100-M104 PolarHBondContact CD2-O 3.01Å; R102-M104 VanDerWaalsContact C-N 3.3Å; R102-M104 HydrophobicContact CB-CE 4.47Å; R102-M104 HydrophobicContact CB-CG 4.12Å; R102-M104 HydrophobicContact CB-SD 4.48Å
105F98.5Very high98.5Very high31 Ų3121.4 Ų21.414%0.13612%0.122CC..EExtended strand (participates in β ladder)trans-133.7141.1-173.6-55-84.3000110.9W16 K57 A58 L59 M99 G103 D209W16-F105 HydrophobicContact CB-CD1 4.44Å; W16-F105 HydrophobicContact CB-CD2 3.85Å; W16-F105 HydrophobicContact CB-CE1 4.01Å; W16-F105 HydrophobicContact CB-CE2 3.38Å; W16-F105 HydrophobicContact CB-CG 4.37Å; W16-F105 HydrophobicContact CB-CZ 3.46Å; W16-F105 VanDerWaalsContact CB-CZ 3.46Å; W16-F105 AromaticContact CD1-CD1 3.71Å; W16-F105 AromaticContact CD1-CE1 3.6Å; W16-F105 AromaticContact CD1-CZ 3.99Å; W16-F105 HydrophobicContact CD2-CB 4.07Å; W16-F105 AromaticContact CD2-CD1 3.97Å; W16-F105 HydrophobicContact CD2-CD1 3.97Å; W16-F105 AromaticContact CD2-CD2 3.78Å; W16-F105 HydrophobicContact CD2-CD2 3.78Å; W16-F105 HydrophobicContact CD2-CE1 4.4Å; W16-F105 HydrophobicContact CD2-CE2 4.25Å; W16-F105 AromaticContact CD2-CG 3.64Å; W16-F105 HydrophobicContact CD2-CG 3.64Å; W16-F105 AromaticContact CE2-CD1 3.99Å; W16-F105 AromaticContact CE2-CG 3.93Å; W16-F105 HydrophobicContact CE3-CB 4.1Å; W16-F105 AromaticContact CE3-CD2 3.89Å; W16-F105 HydrophobicContact CE3-CD2 3.89Å; W16-F105 AromaticContact CE3-CG 3.98Å; W16-F105 HydrophobicContact CE3-CG 3.98Å; W16-F105 AromaticContact CG-CD1 3.8Å; W16-F105 HydrophobicContact CG-CD1 3.8Å; W16-F105 AromaticContact CG-CD2 3.78Å; W16-F105 HydrophobicContact CG-CD2 3.78Å; W16-F105 AromaticContact CG-CE1 3.74Å; W16-F105 HydrophobicContact CG-CE1 3.74Å; W16-F105 AromaticContact CG-CE2 3.75Å; W16-F105 HydrophobicContact CG-CE2 3.75Å; W16-F105 AromaticContact CG-CG 3.82Å; W16-F105 HydrophobicContact CG-CG 3.82Å; W16-F105 AromaticContact CG-CZ 3.72Å; W16-F105 HydrophobicContact CG-CZ 3.72Å; W16-F105 HydrophobicContact CH2-CB 4.24Å; W16-F105 HydrophobicContact CZ2-CB 4.13Å; W16-F105 HydrophobicContact CZ2-CG 4.47Å; W16-F105 HydrophobicContact CZ3-CB 4.23Å; W16-F105 AromaticContact NE1-CD1 3.81Å; K57-F105 WeakPolarHBondContact O-CD2 3.33Å; K57-F105 PolarHBondContact O-N 3.01Å; A58-F105 WeakPolarHBondContact CA-O 3.41Å; A58-F105 HydrophobicContact CB-CB 4.42Å; L59-F105 PolarHBondContact N-O 3.48Å; M99-F105 WeakPolarHBondContact CE-O 3.29Å; G103-F105 WeakPolarHBondContact O-CE2 3.27Å; F105-D209 VanDerWaalsContact CA-OD2 3.23Å; F105-D209 WeakPolarHBondContact CA-OD2 3.17Å; F105-D209 HydrophobicContact CB-CB 3.94Å; F105-D209 HydrophobicContact CD1-CB 4.19Å
106L98.8Very high98.5Very high0 Ų021.4 Ų21.40%012%0.122CC..EExtended strand (participates in β ladder)trans-110.2125.7178.3-173.667.3000111.3L59 I61 L92 I96 M99 D209L59-L106 HydrophobicContact CB-CD1 4.22Å; I61-L106 HydrophobicContact CD1-CD1 4.13Å; I61-L106 HydrophobicContact CD1-CD2 4.26Å; I61-L106 HydrophobicContact CG1-CD1 4.11Å; I61-L106 HydrophobicContact CG2-CD1 3.91Å; L92-L106 HydrophobicContact CD1-CD2 3.82Å; I96-L106 HydrophobicContact CD1-CD2 4.02Å; I96-L106 HydrophobicContact CG1-CB 4.32Å; I96-L106 HydrophobicContact CG1-CD2 3.51Å; M99-L106 HydrophobicContact CE-CB 3.89Å; M99-L106 HydrophobicContact CE-CD1 4.14Å; M99-L106 HydrophobicContact SD-CB 4.1Å; M99-L106 HydrophobicContact SD-CD1 4.08Å; L106-D209 PolarHBondContact N-OD2 3.35Å; L106-D209 WeakPolarHBondContact O-CB 3.42Å; L106-D209 PolarHBondContact O-N 3.21Å
107V98.9Very high98.5Very high0 Ų022.6 Ų22.60%013%0.128CC..EExtended strand (participates in β ladder)trans-107.2127.6171.2176.70000108.6W16 L59 W60 I61 G210 F283 M285W16-V107 HydrophobicContact CH2-CG2 3.74Å; W16-V107 HydrophobicContact CZ2-CG2 4.44Å; L59-V107 PolarHBondContact O-N 2.89Å; W60-V107 WeakPolarHBondContact CA-O 3.31Å; W60-V107 HydrophobicContact CB-CB 4.19Å; W60-V107 HydrophobicContact CB-CG1 4.37Å; W60-V107 HydrophobicContact CG-CG1 4.46Å; I61-V107 PolarHBondContact N-O 2.93Å; V107-G210 WeakPolarHBondContact CA-O 3.36Å; V107-F283 HydrophobicContact CG1-CD1 4.21Å; V107-F283 HydrophobicContact CG1-CE1 4.39Å; V107-F283 HydrophobicContact CG2-CD1 3.75Å; V107-F283 HydrophobicContact CG2-CE1 4.32Å; V107-M285 HydrophobicContact CG1-CE 4.42Å
108M98.8Very high98.5Very high2 Ų224.6 Ų24.61%0.0113%0.133CC..EExtended strand (participates in β ladder)trans-96146.3173.9-69.5-169.779.300111.3V64 Y65 L92 W203 V208 G210 F211 R212V64-M108 HydrophobicContact CG2-CE 3.99Å; Y65-M108 HydrophobicContact CD1-CE 4.3Å; Y65-M108 HydrophobicContact CE1-CE 3.42Å; Y65-M108 VanDerWaalsContact CE1-CE 3.42Å; L92-M108 HydrophobicContact CD2-CE 4.03Å; L92-M108 HydrophobicContact CD2-SD 4.05Å; M108-W203 HydrophobicContact CE-CD2 4.24Å; M108-W203 HydrophobicContact CE-CE3 4.31Å; M108-W203 HydrophobicContact SD-CB 4.23Å; M108-W203 HydrophobicContact SD-CD2 3.82Å; M108-W203 HydrophobicContact SD-CE3 3.86Å; M108-W203 HydrophobicContact SD-CG 3.99Å; M108-V208 HydrophobicContact CB-CG1 4.29Å; M108-V208 HydrophobicContact CG-CG1 3.96Å; M108-V208 HydrophobicContact CG-CG2 3.89Å; M108-V208 HydrophobicContact SD-CG1 4.47Å; M108-V208 HydrophobicContact SD-CG2 3.56Å; M108-V208 VanDerWaalsContact SD-CG2 3.56Å; M108-G210 PolarHBondContact N-O 2.94Å; M108-F211 HydrophobicContact CB-CD1 4.2Å; M108-F211 HydrophobicContact CB-CE1 4.38Å; M108-F211 CarbonylContact O-C 3.47Å; M108-F211 VanDerWaalsContact O-CA 3.26Å; M108-F211 WeakPolarHBondContact O-CA 3.49Å; M108-R212 PolarHBondContact O-N 3.27Å
109D98.7Very high98.5Very high1 Ų122.4 Ų22.41%0.00512%0.123CC..EExtended strand (participates in β ladder)trans-80.6120.4169-154.3-28.8000110W60 I61 P63 Y65 Y74 R212W60-D109 WeakPolarHBondContact CZ2-OD2 3.29Å; W60-D109 PolarHBondContact NE1-OD2 2.75Å; I61-D109 WeakPolarHBondContact O-CB 3.11Å; I61-D109 PolarHBondContact O-N 3.01Å; P63-D109 HydrophobicContact CG-CB 4Å; Y65-D109 WeakPolarHBondContact CE2-O 3.31Å; Y65-D109 PolarHBondContact OH-O 3.29Å; Y65-D109 VanDerWaalsContact OH-O 3.1Å; Y74-D109 PolarHBondContact OH-OD2 3.43Å; D109-R212 WeakPolarHBondContact OD1-CD 3.48Å; D109-R212 IonicContact OD1-CZ 2.88Å; D109-R212 IonicContact OD1-NE 3.55Å; D109-R212 IonicContact OD1-NH1 3.99Å; D109-R212 PolarHBondContact OD1-NH1 3.18Å; D109-R212 IonicContact OD2-CZ 3.62Å; D109-R212 IonicContact OD2-NH1 3.65Å; D109-R212 PolarHBondContact OD2-NH1 2.71Å
110M98.5Very high98.5Very high0 Ų026.3 Ų26.30%015%0.148CC..EExtended strand (participates in β ladder)trans-113.1133.6180-174.463.764.300110.2Y65 Y79 P112 M196 I199 F200 F211 R212 D214Y65-M110 WeakPolarHBondContact OH-CE 3.28Å; Y79-M110 HydrophobicContact CD1-SD 3.84Å; Y79-M110 HydrophobicContact CE1-SD 3.83Å; M110-P112 WeakPolarHBondContact O-CD 3.36Å; M110-M196 HydrophobicContact SD-SD 4.28Å; M110-I199 HydrophobicContact CE-CG2 3.7Å; M110-I199 HydrophobicContact SD-CG2 3.92Å; M110-F200 HydrophobicContact CB-CE1 3.83Å; M110-F200 HydrophobicContact CB-CZ 4.38Å; M110-F200 HydrophobicContact CE-CD1 4Å; M110-F200 HydrophobicContact CE-CE1 4.13Å; M110-F200 HydrophobicContact CG-CD1 4.24Å; M110-F200 HydrophobicContact CG-CE1 3.44Å; M110-F200 VanDerWaalsContact CG-CE1 3.44Å; M110-F200 HydrophobicContact CG-CZ 3.7Å; M110-F200 HydrophobicContact SD-CE1 4.49Å; M110-F211 HydrophobicContact CB-CD1 4.34Å; M110-F211 HydrophobicContact CE-CD1 4.17Å; M110-F211 HydrophobicContact CE-CE1 4.03Å; M110-R212 PolarHBondContact N-O 3.49Å; M110-D214 VanDerWaalsContact O-CB 3.3Å; M110-D214 WeakPolarHBondContact O-CB 3.22Å; M110-D214 PolarHBondContact O-N 2.73Å
111V98.6Very high98.5Very high0 Ų023.7 Ų23.70%014%0.135CC..  trans-111.483.8-176.8-172.50000111P63 Y74 I76 Y79 D214P63-V111 HydrophobicContact CG-CG2 4.24Å; Y74-V111 HydrophobicContact CD1-CG2 3.64Å; Y74-V111 HydrophobicContact CE1-CG2 4.11Å; I76-V111 HydrophobicContact CD1-CB 3.84Å; I76-V111 HydrophobicContact CD1-CG2 3.9Å; Y79-V111 PolarHBondContact OH-O 2.9Å; V111-D214 HydrophobicContact CB-CB 4.41Å; V111-D214 HydrophobicContact CG2-CB 4.02Å
112P98.3Very high98.5Very high0 Ų019.9 Ų19.90%010%0.103CC..  trans-76.6-24.3-177.230-37.4000114.4M110 H114 L185 Y187 M196 I213 D214 V219 W267M110-P112 WeakPolarHBondContact O-CD 3.36Å; P112-H114 PolarHBondContact O-N 3.12Å; P112-L185 WeakPolarHBondContact O-CD1 3.42Å; P112-Y187 HydrophobicContact CB-CE2 4.46Å; P112-Y187 WeakPolarHBondContact CB-OH 3.45Å; P112-Y187 WeakPolarHBondContact O-CE2 3.45Å; P112-Y187 PolarHBondContact O-OH 2.67Å; P112-M196 HydrophobicContact CB-CE 4.42Å; P112-M196 HydrophobicContact CB-SD 4.49Å; P112-I213 HydrophobicContact CG-CG2 3.64Å; P112-D214 WeakPolarHBondContact CD-O 3.24Å; P112-V219 HydrophobicContact CB-CG1 4.33Å; P112-V219 HydrophobicContact CG-CG1 3.98Å; P112-W267 HydrophobicContact CB-CH2 3.6Å; P112-W267 HydrophobicContact CB-CZ2 4.07Å; P112-W267 HydrophobicContact CB-CZ3 4.34Å; P112-W267 HydrophobicContact CG-CH2 3.8Å; P112-W267 HydrophobicContact CG-CZ3 4.12Å
113N98.7Very high98.5Very high0 Ų019.6 Ų19.60%011%0.107CC..SBendtrans-65-38.6-170177.547.7000113.4D184 L185 A215 Y218 V219 K221N113-D184 PolarHBondContact ND2-OD1 2.96Å; N113-D184 WeakPolarHBondContact O-CA 3.35Å; N113-L185 PolarHBondContact O-N 3.27Å; N113-A215 HydrophobicContact CB-CB 4.13Å; N113-Y218 PolarHBondContact OD1-O 3.23Å; N113-V219 HydrophobicContact CB-CG1 4.2Å; N113-K221 PolarHBondContact OD1-NZ 3.17Å
114H98.8Very high98.6Very high2 Ų218.4 Ų18.41%0.0099%0.094CC..BIsolated β-bridgetrans-145173.1-172.151.4-93.7000111.4Y74 Y79 P112 F178 Q182 P183Y74-H114 PolarHBondContact O-NE2 3.22Å; Y79-H114 PolarHBondContact OH-O 3.16Å; P112-H114 PolarHBondContact O-N 3.12Å; H114-F178 AromaticContact CE1-CD2 3.38Å; H114-F178 WeakPolarHBondContact CE1-CD2 3.43Å; H114-F178 AromaticContact CE1-CE2 3.63Å; H114-F178 AromaticContact ND1-CD2 3.68Å; H114-F178 AromaticContact ND1-CE2 3.97Å; H114-Q182 HydrophobicContact CB-CB 4.31Å; H114-Q182 PolarHBondContact NE2-NE2 3.19Å; H114-P183 VanDerWaalsContact CA-O 3.27Å; H114-P183 WeakPolarHBondContact CA-O 3.42Å; H114-P183 WeakPolarHBondContact CB-O 3.4Å
115T98.8Very high98.6Very high0 Ų018.2 Ų18.20%09%0.093CC..  trans-127.7-176.3166.776.40000108.6I76 Y79 H119 W121 Y136 Q182 P183 L185I76-T115 WeakPolarHBondContact O-CB 3.4Å; Y79-T115 HydrophobicContact CE2-CG2 3.82Å; T115-H119 VanDerWaalsContact OG1-CB 3.32Å; T115-H119 WeakPolarHBondContact OG1-CB 3.43Å; T115-W121 HydrophobicContact CG2-CE3 4.27Å; T115-W121 HydrophobicContact CG2-CZ3 4.48Å; T115-Y136 HydrophobicContact CG2-CE1 4.32Å; T115-Y136 WeakPolarHBondContact CG2-OH 3.17Å; T115-Y136 WeakPolarHBondContact OG1-CE1 3.48Å; T115-Y136 PolarHBondContact OG1-OH 2.95Å; T115-Q182 VanDerWaalsContact O-CA 3.28Å; T115-Q182 WeakPolarHBondContact O-CA 3.46Å; T115-P183 PolarHBondContact N-O 3.42Å; T115-P183 VanDerWaalsContact O-CD 3.23Å; T115-P183 WeakPolarHBondContact O-CD 3.38Å; T115-L185 HydrophobicContact CG2-CD1 3.88Å; T115-L185 HydrophobicContact CG2-CD2 3.99Å; T115-L185 HydrophobicContact CG2-CG 4.01Å
116S98.7Very high98.6Very high0 Ų017.4 Ų17.40%09%0.091CC..  trans-71.1147.4165.2177.10000111.8P68 D75 I76 K118 H119 E181P68-S116 WeakPolarHBondContact CG-OG 3.2Å; D75-S116 WeakPolarHBondContact O-CB 3.28Å; I76-S116 WeakPolarHBondContact O-CB 3.4Å; I76-S116 PolarHBondContact O-N 2.86Å; S116-K118 PolarHBondContact O-N 3.5Å; S116-K118 PolarHBondContact OG-N 2.85Å; S116-H119 WeakPolarHBondContact O-CB 3.13Å; S116-H119 PolarHBondContact O-N 2.83Å; S116-E181 CarbonylContact C-O 3.22Å; S116-E181 VanDerWaalsContact CA-O 3.29Å; S116-E181 WeakPolarHBondContact CA-O 3.41Å
117D98.5Very high98.5Very high24 Ų2423.3 Ų23.313%0.12812%0.119CC..THydrogen-bonded Turntrans-60.4-11.3164.882-39.2000113.5F122 E181 P183D117-F122 HydrophobicContact CB-CD1 3.97Å; D117-F122 HydrophobicContact CB-CE1 3.85Å; D117-F122 WeakPolarHBondContact O-CD1 3.21Å; D117-E181 PolarHBondContact N-O 3.15Å; D117-P183 HydrophobicContact CB-CG 4.43Å
118K98.6Very high98.4Very high115 Ų11529.4 Ų29.450%0.514%0.142SC..THydrogen-bonded Turntrans-93.9-3.1170.8-52-48.5178.4-141.80113.4P68 S116P68-K118 HydrophobicContact CG-CB 3.95Å; P68-K118 HydrophobicContact CG-CG 3.82Å; S116-K118 PolarHBondContact O-N 3.5Å; S116-K118 PolarHBondContact OG-N 2.85Å
119H98.7Very high98.3Very high8 Ų833.5 Ų33.54%0.03716%0.161CC..SBendtrans-63.3134.5176.9-167-72.6000110I76 S77 Y79 T115 S116 W121 F122 L123I76-H119 PolarHBondContact O-CD2 2.95Å; S77-H119 VanDerWaalsContact C-CD2 3.42Å; S77-H119 PolarHBondContact O-CD2 3.04Å; Y79-H119 AromaticContact CD2-NE2 3.86Å; T115-H119 VanDerWaalsContact OG1-CB 3.32Å; T115-H119 WeakPolarHBondContact OG1-CB 3.43Å; S116-H119 WeakPolarHBondContact O-CB 3.13Å; S116-H119 PolarHBondContact O-N 2.83Å; H119-W121 AromaticContact CE1-CD1 3.73Å; H119-W121 AromaticContact CE1-CD2 3.13Å; H119-W121 AromaticContact CE1-CE2 3.5Å; H119-W121 AromaticContact CE1-CE3 3.48Å; H119-W121 VanDerWaalsContact CE1-CE3 3.48Å; H119-W121 AromaticContact CE1-CG 3.32Å; H119-W121 AromaticContact CE1-NE1 3.8Å; H119-W121 WeakPolarHBondContact ND1-CB 3.28Å; H119-W121 AromaticContact ND1-CD1 3.97Å; H119-W121 AromaticContact ND1-CD2 3.56Å; H119-W121 AromaticContact ND1-CE3 3.86Å; H119-W121 AromaticContact ND1-CG 3.34Å; H119-W121 VanDerWaalsContact ND1-CG 3.34Å; H119-W121 PolarHBondContact ND1-N 3.29Å; H119-W121 VanDerWaalsContact ND1-N 3.14Å; H119-W121 PolarHBondContact O-N 2.84Å; H119-W121 VanDerWaalsContact O-N 3.12Å; H119-F122 PolarHBondContact O-N 2.73Å; H119-L123 PolarHBondContact O-N 2.96Å
120P98.4Very high97.9Very high81 Ų8142.8 Ų42.853%0.52620%0.204SC..Hα-helixtrans-51.8-39.3-179-30.635.9000114S77 F122 L123 A124S77-P120 WeakPolarHBondContact O-CD 3.45Å; P120-F122 VanDerWaalsContact C-N 3.35Å; P120-F122 PolarHBondContact O-N 3.17Å; P120-L123 PolarHBondContact O-N 3.12Å; P120-A124 WeakPolarHBondContact O-CB 3.35Å; P120-A124 PolarHBondContact O-N 3.37Å
121W98.6Very high97.6Very high18 Ų1848 Ų487%0.06823%0.227CC..Hα-helixtrans-56.1-43.8173.2-58-17.8000113.2T115 H119 S125 F132 F135 Y136 L185 E195 I199T115-W121 HydrophobicContact CG2-CE3 4.27Å; T115-W121 HydrophobicContact CG2-CZ3 4.48Å; H119-W121 AromaticContact CE1-CD1 3.73Å; H119-W121 AromaticContact CE1-CD2 3.13Å; H119-W121 AromaticContact CE1-CE2 3.5Å; H119-W121 AromaticContact CE1-CE3 3.48Å; H119-W121 VanDerWaalsContact CE1-CE3 3.48Å; H119-W121 AromaticContact CE1-CG 3.32Å; H119-W121 AromaticContact CE1-NE1 3.8Å; H119-W121 WeakPolarHBondContact ND1-CB 3.28Å; H119-W121 AromaticContact ND1-CD1 3.97Å; H119-W121 AromaticContact ND1-CD2 3.56Å; H119-W121 AromaticContact ND1-CE3 3.86Å; H119-W121 AromaticContact ND1-CG 3.34Å; H119-W121 VanDerWaalsContact ND1-CG 3.34Å; H119-W121 PolarHBondContact ND1-N 3.29Å; H119-W121 VanDerWaalsContact ND1-N 3.14Å; H119-W121 PolarHBondContact O-N 2.84Å; H119-W121 VanDerWaalsContact O-N 3.12Å; W121-S125 WeakPolarHBondContact O-CB 3.4Å; W121-S125 PolarHBondContact O-N 2.95Å; W121-F132 HydrophobicContact CB-CD1 4.4Å; W121-F132 AromaticContact CD1-CD1 3.77Å; W121-F132 AromaticContact CD1-CE1 3.45Å; W121-F132 VanDerWaalsContact CD1-CE1 3.45Å; W121-F132 HydrophobicContact CG-CD1 4.24Å; W121-F132 HydrophobicContact CG-CE1 4.31Å; W121-F132 AromaticContact NE1-CE1 3.87Å; W121-F135 HydrophobicContact CB-CD1 3.95Å; W121-F135 AromaticContact CD2-CD1 3.77Å; W121-F135 HydrophobicContact CD2-CD1 3.77Å; W121-F135 AromaticContact CD2-CE1 3.85Å; W121-F135 HydrophobicContact CD2-CE1 3.85Å; W121-F135 AromaticContact CE3-CD1 3.97Å; W121-F135 HydrophobicContact CE3-CD1 3.97Å; W121-F135 HydrophobicContact CE3-CE1 4.26Å; W121-F135 AromaticContact CG-CD1 3.8Å; W121-F135 HydrophobicContact CG-CD1 3.8Å; W121-F135 HydrophobicContact CG-CE1 4.04Å; W121-Y136 HydrophobicContact CB-CE2 3.86Å; W121-L185 HydrophobicContact CE3-CD2 4.26Å; W121-E195 HydrophobicContact CH2-CB 3.7Å; W121-E195 HydrophobicContact CH2-CG 4.46Å; W121-E195 HydrophobicContact CZ2-CB 3.76Å; W121-E195 HydrophobicContact CZ2-CG 4.05Å; W121-I199 HydrophobicContact CH2-CD1 3.68Å; W121-I199 HydrophobicContact CZ2-CD1 4.47Å
122F98.7Very high97.6Very high10 Ų1049.9 Ų49.94%0.04424%0.235CC..Hα-helixtrans-70.6-42-178.7-178.2-103000111.2D117 H119 P120 A124 S125 C126 Y136 W138 Y174 P183D117-F122 HydrophobicContact CB-CD1 3.97Å; D117-F122 HydrophobicContact CB-CE1 3.85Å; D117-F122 WeakPolarHBondContact O-CD1 3.21Å; H119-F122 PolarHBondContact O-N 2.73Å; P120-F122 VanDerWaalsContact C-N 3.35Å; P120-F122 PolarHBondContact O-N 3.17Å; F122-A124 VanDerWaalsContact C-N 3.33Å; F122-A124 PolarHBondContact O-N 3.16Å; F122-S125 CarbonylContact O-C 3.46Å; F122-S125 WeakPolarHBondContact O-CB 3.43Å; F122-S125 PolarHBondContact O-N 3.3Å; F122-C126 WeakPolarHBondContact CE1-SG 3.35Å; F122-C126 VanDerWaalsContact CZ-SG 3.58Å; F122-C126 PolarHBondContact O-N 3.33Å; F122-C126 PolarHBondContact O-SG 3.27Å; F122-Y136 HydrophobicContact CB-CD2 4.33Å; F122-Y136 HydrophobicContact CB-CE1 4.2Å; F122-Y136 HydrophobicContact CB-CE2 3.71Å; F122-Y136 AromaticContact CD2-CD1 3.89Å; F122-Y136 HydrophobicContact CD2-CD1 3.89Å; F122-Y136 AromaticContact CD2-CD2 3.92Å; F122-Y136 HydrophobicContact CD2-CD2 3.92Å; F122-Y136 HydrophobicContact CD2-CE1 4.05Å; F122-Y136 HydrophobicContact CD2-CE2 4.13Å; F122-Y136 AromaticContact CD2-CG 3.82Å; F122-Y136 HydrophobicContact CD2-CG 3.82Å; F122-Y136 HydrophobicContact CG-CE2 4.43Å; F122-Y136 VanDerWaalsContact N-CE2 3.34Å; F122-Y136 PolarHBondContact N-OH 2.83Å; F122-W138 HydrophobicContact CD2-CZ2 4.32Å; F122-W138 AromaticContact CE2-CH2 3.9Å; F122-W138 HydrophobicContact CE2-CH2 3.9Å; F122-W138 AromaticContact CE2-CZ2 3.73Å; F122-W138 HydrophobicContact CE2-CZ2 3.73Å; F122-W138 HydrophobicContact CZ-CH2 4.03Å; F122-W138 HydrophobicContact CZ-CZ2 4.27Å; F122-Y174 HydrophobicContact CE2-CD1 4.36Å; F122-Y174 HydrophobicContact CE2-CD2 4.03Å; F122-Y174 HydrophobicContact CE2-CE2 4.38Å; F122-Y174 HydrophobicContact CE2-CG 4Å; F122-Y174 AromaticContact CZ-CD1 3.97Å; F122-Y174 HydrophobicContact CZ-CD1 3.97Å; F122-Y174 HydrophobicContact CZ-CD2 4.11Å; F122-Y174 AromaticContact CZ-CE1 3.95Å; F122-Y174 HydrophobicContact CZ-CE1 3.95Å; F122-Y174 HydrophobicContact CZ-CE2 4.07Å; F122-Y174 HydrophobicContact CZ-CG 4.04Å; F122-Y174 AromaticContact CZ-CZ 3.98Å; F122-P183 HydrophobicContact CB-CG 4.35Å; F122-P183 HydrophobicContact CD1-CG 4.37Å; F122-P183 HydrophobicContact CD2-CB 3.58Å; F122-P183 HydrophobicContact CD2-CG 3.44Å; F122-P183 VanDerWaalsContact CD2-CG 3.44Å; F122-P183 HydrophobicContact CE2-CB 3.43Å; F122-P183 VanDerWaalsContact CE2-CB 3.43Å; F122-P183 HydrophobicContact CE2-CG 3.69Å; F122-P183 HydrophobicContact CG-CB 4.42Å; F122-P183 HydrophobicContact CG-CG 3.8Å; F122-P183 HydrophobicContact CZ-CB 4.16Å; F122-P183 HydrophobicContact CZ-CG 4.22Å
123L98.4Very high97.5Very high83 Ų8350.7 Ų50.744%0.43524%0.242SC..Hα-helixtrans-61.2-40.6177.1-62.4176.6000112.3H119 P120 Q127H119-L123 PolarHBondContact O-N 2.96Å; P120-L123 PolarHBondContact O-N 3.12Å; L123-Q127 PolarHBondContact O-NE2 3.45Å; L123-Q127 VanDerWaalsContact O-NE2 3.13Å
124A98.3Very high97.4Very high7 Ų755.2 Ų55.26%0.05827%0.266CS..Hα-helixtrans-70.4-39.4174.200000111.8P120 F122 Q127 R128 E129 F132P120-A124 WeakPolarHBondContact O-CB 3.35Å; P120-A124 PolarHBondContact O-N 3.37Å; F122-A124 VanDerWaalsContact C-N 3.33Å; F122-A124 PolarHBondContact O-N 3.16Å; A124-Q127 CarbonylContact O-C 3.59Å; A124-Q127 PolarHBondContact O-N 3.45Å; A124-Q127 VanDerWaalsContact O-N 3.12Å; A124-R128 PolarHBondContact O-N 3.24Å; A124-E129 HydrophobicContact CB-CB 4.15Å; A124-E129 HydrophobicContact CB-CG 4.23Å; A124-E129 PolarHBondContact O-N 3.33Å; A124-E129 VanDerWaalsContact O-N 3.12Å; A124-F132 HydrophobicContact CB-CB 3.73Å; A124-F132 HydrophobicContact CB-CD2 3.53Å; A124-F132 HydrophobicContact CB-CE2 4.41Å; A124-F132 HydrophobicContact CB-CG 3.88Å
125S98.3Very high97.4Very high0 Ų055.1 Ų55.10%027%0.266CS..Hα-helixtrans-61.7-44174.7-161.20000111.4W121 F122 Q127 R128 F132 A133 W138 R170W121-S125 WeakPolarHBondContact O-CB 3.4Å; W121-S125 PolarHBondContact O-N 2.95Å; F122-S125 CarbonylContact O-C 3.46Å; F122-S125 WeakPolarHBondContact O-CB 3.43Å; F122-S125 PolarHBondContact O-N 3.3Å; S125-Q127 PolarHBondContact O-N 2.92Å; S125-R128 PolarHBondContact O-N 2.93Å; S125-F132 WeakPolarHBondContact CA-O 3.31Å; S125-F132 WeakPolarHBondContact CB-O 3.21Å; S125-F132 PolarHBondContact OG-O 3.35Å; S125-A133 PolarHBondContact OG-O 3.12Å; S125-A133 VanDerWaalsContact OG-O 3.04Å; S125-W138 PolarHBondContact OG-NE1 3.22Å; S125-R170 PolarHBondContact O-NH1 3.08Å
126C97.9Very high97.4Very high14 Ų1455.2 Ų55.210%0.09527%0.266CS..Hα-helixtrans-54.8-28.6174.5-72.90000113.2F122 R170F122-C126 WeakPolarHBondContact CE1-SG 3.35Å; F122-C126 VanDerWaalsContact CZ-SG 3.58Å; F122-C126 PolarHBondContact O-N 3.33Å; F122-C126 PolarHBondContact O-SG 3.27Å; C126-R170 WeakPolarHBondContact O-CB 3.3Å
127Q96.9Very high97.4Very high124 Ų12455.7 Ų55.758%0.57927%0.268SS*.THydrogen-bonded Turntrans-95.52.9-179.9-67.9175.179.600113.8L123 A124 S125 E129L123-Q127 PolarHBondContact O-NE2 3.45Å; L123-Q127 VanDerWaalsContact O-NE2 3.13Å; A124-Q127 CarbonylContact O-C 3.59Å; A124-Q127 PolarHBondContact O-N 3.45Å; A124-Q127 VanDerWaalsContact O-N 3.12Å; S125-Q127 PolarHBondContact O-N 2.92Å; Q127-E129 HydrophobicContact CB-CG 4.23Å; Q127-E129 PolarHBondContact O-N 2.92Å
128R96.4Very high97.4Very high129 Ų12955.6 Ų55.649%0.48727%0.266SS..THydrogen-bonded Turntrans56.335-175-57.9177.5179.3-991.9113A124 S125 E130 R170 Q172A124-R128 PolarHBondContact O-N 3.24Å; S125-R128 PolarHBondContact O-N 2.93Å; R128-E130 PolarHBondContact O-N 3.24Å; R128-R170 HydrophobicContact CG-CG 4.28Å; R128-R170 PolarHBondContact NH2-O 3.46Å; R128-Q172 VanDerWaalsContact NH2-OE1 3.07Å
129E97.2Very high97.4Very high87 Ų8753.3 Ų53.341%0.40726%0.256SS..  trans-61.8127.5172.7-68-179.7-147.500109.9A124 Q127 K131 F132 A133A124-E129 HydrophobicContact CB-CB 4.15Å; A124-E129 HydrophobicContact CB-CG 4.23Å; A124-E129 PolarHBondContact O-N 3.33Å; A124-E129 VanDerWaalsContact O-N 3.12Å; Q127-E129 HydrophobicContact CB-CG 4.23Å; Q127-E129 PolarHBondContact O-N 2.92Å; E129-K131 VanDerWaalsContact C-N 3.27Å; E129-K131 PolarHBondContact O-N 2.85Å; E129-F132 CarbonylContact O-C 3.53Å; E129-F132 PolarHBondContact O-N 3.49Å; E129-A133 PolarHBondContact O-N 3.47Å
130E90.5Very high97.3Very high196 Ų19658.1 Ų58.192%0.91628%0.283SS*.THydrogen-bonded Turntrans-46.9-42.6-164.9-173.3179.8176.700114.5R128R128-E130 PolarHBondContact O-N 3.24Å
131K93.2Very high97.2Very high110 Ų11055 Ų5548%0.47827%0.265SS..THydrogen-bonded Turntrans-70.7-33.9179.3-177.4177.4173.8-173.60113.3E129 F135 E195E129-K131 VanDerWaalsContact C-N 3.27Å; E129-K131 PolarHBondContact O-N 2.85Å; K131-F135 WeakPolarHBondContact O-CD2 3.31Å; K131-F135 WeakPolarHBondContact O-CE2 3.23Å; K131-E195 IonicContact NZ-OE1 3.83Å
132F97.2Very high97Very high40 Ų4058.3 Ų58.318%0.17528%0.283CS..THydrogen-bonded Turntrans-111.4-2.8-168.7-56.2-69000113.4W121 A124 S125 E129 D134 F135W121-F132 HydrophobicContact CB-CD1 4.4Å; W121-F132 AromaticContact CD1-CD1 3.77Å; W121-F132 AromaticContact CD1-CE1 3.45Å; W121-F132 VanDerWaalsContact CD1-CE1 3.45Å; W121-F132 HydrophobicContact CG-CD1 4.24Å; W121-F132 HydrophobicContact CG-CE1 4.31Å; W121-F132 AromaticContact NE1-CE1 3.87Å; A124-F132 HydrophobicContact CB-CB 3.73Å; A124-F132 HydrophobicContact CB-CD2 3.53Å; A124-F132 HydrophobicContact CB-CE2 4.41Å; A124-F132 HydrophobicContact CB-CG 3.88Å; S125-F132 WeakPolarHBondContact CA-O 3.31Å; S125-F132 WeakPolarHBondContact CB-O 3.21Å; S125-F132 PolarHBondContact OG-O 3.35Å; E129-F132 CarbonylContact O-C 3.53Å; E129-F132 PolarHBondContact O-N 3.49Å; F132-D134 PolarHBondContact O-N 3.3Å; F132-F135 HydrophobicContact CB-CD2 4.48Å; F132-F135 AromaticContact CD1-CD1 3.97Å; F132-F135 HydrophobicContact CD1-CD1 3.97Å; F132-F135 HydrophobicContact CD1-CD2 4.19Å; F132-F135 AromaticContact CD1-CE1 3.78Å; F132-F135 HydrophobicContact CD1-CE1 3.78Å; F132-F135 HydrophobicContact CD1-CE2 4.02Å; F132-F135 HydrophobicContact CD1-CG 4.17Å; F132-F135 AromaticContact CD1-CZ 3.81Å; F132-F135 HydrophobicContact CD1-CZ 3.81Å; F132-F135 HydrophobicContact CE1-CE1 4.08Å; F132-F135 HydrophobicContact CE1-CZ 4.1Å; F132-F135 PolarHBondContact O-N 3Å; F132-F135 VanDerWaalsContact O-N 3.1Å
133A97.1Very high96.8Very high17 Ų1766.2 Ų66.214%0.1432%0.318CS..THydrogen-bonded Turntrans-52.4-36.7-17300000113.2S125 E129 R170S125-A133 PolarHBondContact OG-O 3.12Å; S125-A133 VanDerWaalsContact OG-O 3.04Å; E129-A133 PolarHBondContact O-N 3.47Å; A133-R170 PolarHBondContact O-NH1 3.45Å; A133-R170 PolarHBondContact O-NH2 3.07Å; A133-R170 VanDerWaalsContact O-NH2 3.16Å
134D96.9Very high96.4Very high94 Ų9465.9 Ų65.950%0.50331%0.314SS..THydrogen-bonded Turntrans-115.925.8-177.4-61.6-29.3000113.2F132 R170 N186 N189F132-D134 PolarHBondContact O-N 3.3Å; D134-R170 IonicContact OD1-NH2 2.81Å; D134-N186 WeakPolarHBondContact O-CB 3.41Å; D134-N186 PolarHBondContact O-ND2 3.12Å; D134-N186 VanDerWaalsContact O-ND2 3.15Å; D134-N189 WeakPolarHBondContact O-CB 3.38Å; D134-N189 PolarHBondContact O-ND2 2.88Å; D134-N189 VanDerWaalsContact O-ND2 3.14Å
135F98.6Very high96.1Very high0 Ų075.6 Ų75.60%036%0.358CS..SBendtrans-71-21.8173.7-92.4-132.5000112.9W121 K131 F132 L185 N186 D191 V192 E195W121-F135 HydrophobicContact CB-CD1 3.95Å; W121-F135 AromaticContact CD2-CD1 3.77Å; W121-F135 HydrophobicContact CD2-CD1 3.77Å; W121-F135 AromaticContact CD2-CE1 3.85Å; W121-F135 HydrophobicContact CD2-CE1 3.85Å; W121-F135 AromaticContact CE3-CD1 3.97Å; W121-F135 HydrophobicContact CE3-CD1 3.97Å; W121-F135 HydrophobicContact CE3-CE1 4.26Å; W121-F135 AromaticContact CG-CD1 3.8Å; W121-F135 HydrophobicContact CG-CD1 3.8Å; W121-F135 HydrophobicContact CG-CE1 4.04Å; K131-F135 WeakPolarHBondContact O-CD2 3.31Å; K131-F135 WeakPolarHBondContact O-CE2 3.23Å; F132-F135 HydrophobicContact CB-CD2 4.48Å; F132-F135 AromaticContact CD1-CD1 3.97Å; F132-F135 HydrophobicContact CD1-CD1 3.97Å; F132-F135 HydrophobicContact CD1-CD2 4.19Å; F132-F135 AromaticContact CD1-CE1 3.78Å; F132-F135 HydrophobicContact CD1-CE1 3.78Å; F132-F135 HydrophobicContact CD1-CE2 4.02Å; F132-F135 HydrophobicContact CD1-CG 4.17Å; F132-F135 AromaticContact CD1-CZ 3.81Å; F132-F135 HydrophobicContact CD1-CZ 3.81Å; F132-F135 HydrophobicContact CE1-CE1 4.08Å; F132-F135 HydrophobicContact CE1-CZ 4.1Å; F132-F135 PolarHBondContact O-N 3Å; F132-F135 VanDerWaalsContact O-N 3.1Å; F135-L185 WeakPolarHBondContact O-CA 3.37Å; F135-L185 WeakPolarHBondContact O-CD2 3.46Å; F135-N186 PolarHBondContact O-N 2.94Å; F135-D191 HydrophobicContact CE2-CB 3.71Å; F135-D191 HydrophobicContact CZ-CB 3.88Å; F135-V192 HydrophobicContact CB-CG2 4.07Å; F135-V192 HydrophobicContact CD1-CG2 3.92Å; F135-V192 HydrophobicContact CD2-CG2 4.02Å; F135-V192 HydrophobicContact CE1-CG2 4.35Å; F135-V192 HydrophobicContact CE2-CG2 4.43Å; F135-V192 HydrophobicContact CG-CG2 3.75Å; F135-E195 HydrophobicContact CE1-CG 4.26Å; F135-E195 HydrophobicContact CZ-CG 4.32Å
136Y98.8Very high95.8Very high2 Ų279.8 Ų79.81%0.00839%0.387CS..BIsolated β-bridgetrans-123.4163.6179.5-61.6-94.3000110.2T115 W121 F122 W138 P183 D184 L185T115-Y136 HydrophobicContact CG2-CE1 4.32Å; T115-Y136 WeakPolarHBondContact CG2-OH 3.17Å; T115-Y136 WeakPolarHBondContact OG1-CE1 3.48Å; T115-Y136 PolarHBondContact OG1-OH 2.95Å; W121-Y136 HydrophobicContact CB-CE2 3.86Å; F122-Y136 HydrophobicContact CB-CD2 4.33Å; F122-Y136 HydrophobicContact CB-CE1 4.2Å; F122-Y136 HydrophobicContact CB-CE2 3.71Å; F122-Y136 AromaticContact CD2-CD1 3.89Å; F122-Y136 HydrophobicContact CD2-CD1 3.89Å; F122-Y136 AromaticContact CD2-CD2 3.92Å; F122-Y136 HydrophobicContact CD2-CD2 3.92Å; F122-Y136 HydrophobicContact CD2-CE1 4.05Å; F122-Y136 HydrophobicContact CD2-CE2 4.13Å; F122-Y136 AromaticContact CD2-CG 3.82Å; F122-Y136 HydrophobicContact CD2-CG 3.82Å; F122-Y136 HydrophobicContact CG-CE2 4.43Å; F122-Y136 VanDerWaalsContact N-CE2 3.34Å; F122-Y136 PolarHBondContact N-OH 2.83Å; Y136-W138 VanDerWaalsContact O-CD1 3.29Å; Y136-W138 PolarHBondContact O-N 2.92Å; Y136-P183 HydrophobicContact CD1-CB 3.72Å; Y136-P183 HydrophobicContact CD1-CG 4.07Å; Y136-P183 HydrophobicContact CE1-CB 4.03Å; Y136-P183 HydrophobicContact CE1-CG 3.84Å; Y136-P183 WeakPolarHBondContact CE1-O 3.37Å; Y136-D184 WeakPolarHBondContact CA-O 3.48Å; Y136-D184 WeakPolarHBondContact CD1-O 3.19Å; Y136-L185 HydrophobicContact CD1-CD2 4.24Å; Y136-L185 HydrophobicContact CE1-CD2 3.75Å; Y136-L185 HydrophobicContact CE1-CG 4.3Å; Y136-L185 HydrophobicContact CE2-CD2 4.33Å
137I98.5Very high95.3Very high10 Ų1082 Ų825%0.05141%0.413CS..  trans-85.8105-178.2-62.7172.3000109.2W164 Y174 L175 D184 N186 K221 F225I137-W164 HydrophobicContact CG2-CH2 4.06Å; I137-W164 HydrophobicContact CG2-CZ3 4.35Å; I137-Y174 WeakPolarHBondContact O-CA 3.46Å; I137-L175 HydrophobicContact CB-CB 4.01Å; I137-L175 HydrophobicContact CB-CD2 4.44Å; I137-L175 HydrophobicContact CD1-CD2 3.94Å; I137-L175 HydrophobicContact CG2-CB 4.02Å; I137-L175 HydrophobicContact CG2-CD2 4.29Å; I137-L175 PolarHBondContact O-N 3.05Å; I137-D184 PolarHBondContact N-O 3.31Å; I137-N186 HydrophobicContact CG1-CB 3.78Å; I137-K221 HydrophobicContact CD1-CD 3.38Å; I137-K221 HydrophobicContact CD1-CG 4.47Å; I137-F225 HydrophobicContact CG2-CE1 3.62Å; I137-F225 HydrophobicContact CG2-CZ 3.78Å
138W98.4Very high95Very high22 Ų2281.2 Ų81.28%0.08341%0.411CS..EExtended strand (participates in β ladder)trans-107.1141176.5-63.699.1000111.2F122 S125 Y136 C167 R170 Q172 F173 Y174F122-W138 HydrophobicContact CD2-CZ2 4.32Å; F122-W138 AromaticContact CE2-CH2 3.9Å; F122-W138 HydrophobicContact CE2-CH2 3.9Å; F122-W138 AromaticContact CE2-CZ2 3.73Å; F122-W138 HydrophobicContact CE2-CZ2 3.73Å; F122-W138 HydrophobicContact CZ-CH2 4.03Å; F122-W138 HydrophobicContact CZ-CZ2 4.27Å; S125-W138 PolarHBondContact OG-NE1 3.22Å; Y136-W138 VanDerWaalsContact O-CD1 3.29Å; Y136-W138 PolarHBondContact O-N 2.92Å; W138-C167 HydrophobicContact CH2-CB 3.84Å; W138-C167 HydrophobicContact CZ3-CB 3.49Å; W138-C167 VanDerWaalsContact CZ3-CB 3.49Å; W138-R170 VanDerWaalsContact CD2-CD 3.47Å; W138-R170 HydrophobicContact CE3-CG 4.38Å; W138-R170 HydrophobicContact CZ3-CB 4.33Å; W138-Q172 HydrophobicContact CE3-CB 3.96Å; W138-F173 CarbonylContact C-O 3.55Å; W138-F173 WeakPolarHBondContact CA-O 3.35Å; W138-Y174 AromaticContact CH2-CD1 3.88Å; W138-Y174 HydrophobicContact CH2-CD1 3.88Å; W138-Y174 HydrophobicContact CH2-CG 4.13Å; W138-Y174 AromaticContact CZ3-CD1 3.75Å; W138-Y174 HydrophobicContact CZ3-CD1 3.75Å; W138-Y174 HydrophobicContact CZ3-CG 4.06Å
139K98Very high95Very high67 Ų6777.4 Ų77.429%0.29140%0.402SS..EExtended strand (participates in β ladder)trans-140.7143.7175.1-69.4-65-179171.60111.6P152 W164 F173 F225K139-P152 HydrophobicContact CB-CB 3.95Å; K139-P152 HydrophobicContact CB-CG 3.77Å; K139-P152 HydrophobicContact CG-CB 4.46Å; K139-P152 HydrophobicContact CG-CG 4.25Å; K139-W164 HydrophobicContact CB-CH2 4.09Å; K139-W164 HydrophobicContact CB-CZ3 3.9Å; K139-W164 HydrophobicContact CG-CH2 3.51Å; K139-W164 HydrophobicContact CG-CZ2 4.44Å; K139-W164 HydrophobicContact CG-CZ3 3.77Å; K139-F173 PolarHBondContact N-O 2.99Å; K139-F173 PolarHBondContact O-N 3.24Å; K139-F225 VanDerWaalsContact NZ-CE2 3.32Å
140D97.3Very high94.9Very high110 Ų11077.5 Ų77.559%0.58840%0.403SS*.  trans-67.9139.9166.8-61.7-31.6000108.9Q172D140-Q172 WeakPolarHBondContact OD1-CG 3.4Å; D140-Q172 PolarHBondContact OD1-NE2 3.36Å
141G95.4Very high95.3Very high16 Ų1670.1 Ų70.117%0.16537%0.372CS..  trans-82164.4173.300000113K143 Q150G141-K143 PolarHBondContact O-N 2.92Å; G141-Q150 CarbonylContact C-O 3.58Å; G141-Q150 WeakPolarHBondContact CA-O 3.42Å
142I95.6Very high95.5Very high86 Ų8666.2 Ų66.244%0.44136%0.358SS..EExtended strand (participates in β ladder)trans-83.1113.2178.5-56.9170.7000108.6Q144 Q150I142-Q144 PolarHBondContact O-N 3.46Å; I142-Q150 PolarHBondContact N-O 3.2Å; I142-Q150 PolarHBondContact O-N 3.25Å
143K93.3Very high95.5Very high177 Ų17764.9 Ų64.977%0.7735%0.352SS*.EExtended strand (participates in β ladder)trans-75.9117.9176.8-64.7-175.4-179.5-179.50110.2G141 V149G141-K143 PolarHBondContact O-N 2.92Å; K143-V149 HydrophobicContact CG-CG2 4.48Å
144Q91.5Very high95.5Very high75 Ų7566.1 Ų66.135%0.3536%0.357SS..  trans-82.2158.3173.4-62.1-67.9-31.200110.8I142 S146 G147 I148 Q150I142-Q144 PolarHBondContact O-N 3.46Å; Q144-S146 PolarHBondContact O-N 3.28Å; Q144-S146 VanDerWaalsContact O-N 3.14Å; Q144-G147 PolarHBondContact O-N 3.04Å; Q144-I148 WeakPolarHBondContact CB-O 3.44Å; Q144-I148 WeakPolarHBondContact CG-O 3.47Å; Q144-I148 PolarHBondContact N-O 3.17Å; Q144-Q150 HydrophobicContact CG-CG 4.01Å
145E91.8Very high95.6Very high211 Ų21161.7 Ų61.799%0.98633%0.333SS*.THydrogen-bonded Turntrans-57.6-27.1174.2-68.1-175169.900112.7G147E145-G147 PolarHBondContact O-N 2.95Å
146S90.8Very high95.5Very high89 Ų8962.9 Ų62.962%0.62234%0.338SS*.THydrogen-bonded Turntrans-71.3-9.2175.261.80000114.5Q144 I148Q144-S146 PolarHBondContact O-N 3.28Å; Q144-S146 VanDerWaalsContact O-N 3.14Å; S146-I148 VanDerWaalsContact C-N 3.31Å; S146-I148 PolarHBondContact OG-N 3.26Å
147G88.6Confident95.3Very high61 Ų6162.9 Ų62.963%0.62934%0.339SS*.SBendtrans85.5-5.6-172.900000114.6Q144 E145Q144-G147 PolarHBondContact O-N 3.04Å; E145-G147 PolarHBondContact O-N 2.95Å
148I91.3Very high94.9Very high107 Ų10763.9 Ų63.955%0.54934%0.344SS..PPolyproline II helixtrans-71133.4174.2-61.6174.1000109.2Q144 S146Q144-I148 WeakPolarHBondContact CB-O 3.44Å; Q144-I148 WeakPolarHBondContact CG-O 3.47Å; Q144-I148 PolarHBondContact N-O 3.17Å; S146-I148 VanDerWaalsContact C-N 3.31Å; S146-I148 PolarHBondContact OG-N 3.26Å
149V94.7Very high94.4Very high48 Ų4863.5 Ų63.529%0.29134%0.343SS..EExtended strand (participates in β ladder)trans-96.7117.8174.1-165.70000108.6K143 W166 F173K143-V149 HydrophobicContact CG-CG2 4.48Å; V149-W166 HydrophobicContact CG1-CH2 4.43Å; V149-W166 HydrophobicContact CG1-CZ3 4.05Å; V149-F173 HydrophobicContact CG1-CE2 3.88Å
150Q96.4Very high93.8Very high89 Ų8961.6 Ų61.642%0.41634%0.343SS..EExtended strand (participates in β ladder)trans-94.3155.8177.2-69.2-176.18.100111.5G141 I142 Q144 F173G141-Q150 CarbonylContact C-O 3.58Å; G141-Q150 WeakPolarHBondContact CA-O 3.42Å; I142-Q150 PolarHBondContact N-O 3.2Å; I142-Q150 PolarHBondContact O-N 3.25Å; Q144-Q150 HydrophobicContact CG-CG 4.01Å; Q150-F173 WeakPolarHBondContact O-CE2 3.15Å
151P97.8Very high93.5Very high41 Ų4158.3 Ų58.327%0.26634%0.335SS..PPolyproline II helixtrans-49.5153.2168.5-29.937.7000113N153 W164 F173P151-N153 VanDerWaalsContact C-N 3.27Å; P151-N153 PolarHBondContact O-N 3.42Å; P151-W164 HydrophobicContact CB-CB 3.93Å; P151-W164 HydrophobicContact CB-CG 4.1Å; P151-W164 HydrophobicContact CG-CB 4.33Å; P151-F173 HydrophobicContact CG-CE1 4.09Å; P151-F173 HydrophobicContact CG-CZ 4.32Å
152P97.5Very high93.5Very high29 Ų2959.9 Ų59.919%0.18834%0.343CS..SBendtrans-68.7-22.5-176.830.1-39.1000114.1K139 W164K139-P152 HydrophobicContact CB-CB 3.95Å; K139-P152 HydrophobicContact CB-CG 3.77Å; K139-P152 HydrophobicContact CG-CB 4.46Å; K139-P152 HydrophobicContact CG-CG 4.25Å; P152-W164 HydrophobicContact CG-CD2 3.57Å; P152-W164 HydrophobicContact CG-CE3 3.91Å; P152-W164 HydrophobicContact CG-CG 4.13Å; P152-W164 HydrophobicContact CG-CH2 3.89Å; P152-W164 HydrophobicContact CG-CZ2 3.55Å; P152-W164 HydrophobicContact CG-CZ3 4.06Å
153N98.2Very high93.6Very high11 Ų1155.8 Ų55.86%0.05932%0.323CS..SBendtrans-157.1177.4176.565.333.2000111P151 W155 W164 F225 D227P151-N153 VanDerWaalsContact C-N 3.27Å; P151-N153 PolarHBondContact O-N 3.42Å; N153-W155 VanDerWaalsContact C-N 3.32Å; N153-W155 PolarHBondContact O-N 3.41Å; N153-W155 WeakPolarHBondContact OD1-CB 3.4Å; N153-W155 PolarHBondContact OD1-N 3.07Å; N153-W155 VanDerWaalsContact OD1-N 3.13Å; N153-W164 PolarHBondContact OD1-NE1 2.92Å; N153-F225 WeakPolarHBondContact CB-O 3.37Å; N153-F225 PolarHBondContact ND2-O 3.24Å; N153-D227 VanDerWaalsContact CA-OD1 3.23Å; N153-D227 WeakPolarHBondContact CA-OD1 3.4Å; N153-D227 VanDerWaalsContact CB-OD1 3.29Å; N153-D227 WeakPolarHBondContact CB-OD1 3.49Å
154N97.1Very high93.9Very high44 Ų4447.8 Ų47.824%0.23529%0.287CS..  trans-85.916-175.974.3-6.1000115.3E156 D227 N228 T249N154-E156 PolarHBondContact O-N 3.47Å; N154-D227 PolarHBondContact N-OD1 3.31Å; N154-D227 VanDerWaalsContact OD1-CA 3.26Å; N154-D227 WeakPolarHBondContact OD1-CA 3.24Å; N154-D227 WeakPolarHBondContact OD1-CB 3.15Å; N154-D227 PolarHBondContact OD1-OD1 2.98Å; N154-N228 PolarHBondContact ND2-O 3.12Å; N154-N228 PolarHBondContact OD1-N 3.01Å; N154-T249 HydrophobicContact CB-CG2 4.42Å; N154-T249 WeakPolarHBondContact ND2-CG2 3.33Å
155W97.9Very high94.2Very high1 Ų147.7 Ų47.70%0.00429%0.287CS..  trans-63.1137.9-178.3-64.7-3.8000111.9N153 A163 W164 L175 K221 F225 A226 N228 N254N153-W155 VanDerWaalsContact C-N 3.32Å; N153-W155 PolarHBondContact O-N 3.41Å; N153-W155 WeakPolarHBondContact OD1-CB 3.4Å; N153-W155 PolarHBondContact OD1-N 3.07Å; N153-W155 VanDerWaalsContact OD1-N 3.13Å; W155-A163 HydrophobicContact CB-CB 4.12Å; W155-A163 PolarHBondContact O-N 3.39Å; W155-W164 HydrophobicContact CE3-CZ2 4.01Å; W155-W164 HydrophobicContact CZ3-CZ2 4.16Å; W155-L175 HydrophobicContact CE3-CD1 3.78Å; W155-L175 HydrophobicContact CE3-CD2 4.45Å; W155-L175 HydrophobicContact CZ3-CD1 4.21Å; W155-L175 HydrophobicContact CZ3-CD2 4.1Å; W155-K221 HydrophobicContact CH2-CB 3.96Å; W155-K221 HydrophobicContact CH2-CG 4.27Å; W155-K221 HydrophobicContact CZ3-CB 4.19Å; W155-K221 HydrophobicContact CZ3-CG 4.04Å; W155-F225 HydrophobicContact CH2-CB 4.44Å; W155-F225 AromaticContact CH2-CD1 3.41Å; W155-F225 HydrophobicContact CH2-CD1 3.41Å; W155-F225 VanDerWaalsContact CH2-CD1 3.41Å; W155-F225 AromaticContact CH2-CE1 3.87Å; W155-F225 HydrophobicContact CH2-CE1 3.87Å; W155-F225 HydrophobicContact CH2-CG 4.12Å; W155-F225 HydrophobicContact CZ2-CD1 4.28Å; W155-F225 AromaticContact CZ3-CD1 3.66Å; W155-F225 HydrophobicContact CZ3-CD1 3.66Å; W155-F225 AromaticContact CZ3-CE1 3.88Å; W155-F225 HydrophobicContact CZ3-CE1 3.88Å; W155-A226 PolarHBondContact NE1-O 2.96Å; W155-N228 VanDerWaalsContact CD1-ND2 3.34Å; W155-N254 HydrophobicContact CD2-CB 3.68Å; W155-N254 HydrophobicContact CE3-CB 3.68Å; W155-N254 HydrophobicContact CG-CB 4.29Å; W155-N254 HydrophobicContact CH2-CB 4.13Å; W155-N254 HydrophobicContact CZ2-CB 4.14Å; W155-N254 HydrophobicContact CZ3-CB 3.91Å
156E96.1Very high94.5Very high24 Ų2440.9 Ų40.911%0.11225%0.252CS..BIsolated β-bridgetrans-104.7142.1-179.5-68.3173.1-82.400111.1N154 G161 M247 L248 T249N154-E156 PolarHBondContact O-N 3.47Å; E156-G161 CarbonylContact C-O 3.41Å; E156-G161 VanDerWaalsContact CA-O 3.25Å; E156-G161 WeakPolarHBondContact CA-O 3.41Å; E156-M247 HydrophobicContact CB-CE 4.14Å; E156-L248 PolarHBondContact OE1-N 2.69Å; E156-L248 PolarHBondContact OE2-N 3.33Å; E156-T249 WeakPolarHBondContact OE1-CB 3.21Å; E156-T249 PolarHBondContact OE1-N 3.13Å; E156-T249 PolarHBondContact OE1-OG1 3.42Å
157S94.9Very high94.8Very high2 Ų237.4 Ų37.41%0.01423%0.228CC..  trans-70.6147.2168164.80000109.7I159 G160 G161 T177 F178S157-I159 PolarHBondContact O-N 2.61Å; S157-I159 WeakPolarHBondContact OG-CG2 3.23Å; S157-I159 PolarHBondContact OG-N 3.42Å; S157-G160 WeakPolarHBondContact O-CA 3.2Å; S157-G160 PolarHBondContact O-N 3.04Å; S157-G161 PolarHBondContact N-O 3.25Å; S157-T177 WeakPolarHBondContact CA-O 3.32Å; S157-T177 PolarHBondContact OG-O 2.88Å; S157-F178 PolarHBondContact OG-O 3.17Å
158I91.3Very high95.2Very high31 Ų3141.3 Ų41.316%0.15923%0.23CC..THydrogen-bonded Turntrans-60.5-30.5177.2-60.7-58.9000111.9G160 T177 F178 Y218I158-G160 PolarHBondContact O-N 3.47Å; I158-T177 HydrophobicContact CG1-CG2 3.94Å; I158-T177 PolarHBondContact N-O 2.77Å; I158-F178 HydrophobicContact CB-CD1 3.91Å; I158-F178 HydrophobicContact CB-CE1 4.09Å; I158-F178 HydrophobicContact CG1-CD1 4.16Å; I158-F178 HydrophobicContact CG1-CE1 4Å; I158-F178 HydrophobicContact CG2-CD1 4.32Å; I158-F178 HydrophobicContact CG2-CE1 4.23Å; I158-Y218 HydrophobicContact CD1-CE1 4.22Å; I158-Y218 WeakPolarHBondContact CD1-OH 3.37Å
159I86.4Confident95.3Very high14 Ų1444.8 Ų44.87%0.07224%0.241CC..THydrogen-bonded Turntrans-84.85.3174.7-167.5173.6000112.4S157 L179 Y400 R403S157-I159 PolarHBondContact O-N 2.61Å; S157-I159 WeakPolarHBondContact OG-CG2 3.23Å; S157-I159 PolarHBondContact OG-N 3.42Å; I159-L179 HydrophobicContact CD1-CD2 3.35Å; I159-L179 HydrophobicContact CG2-CD2 4.16Å; I159-Y400 HydrophobicContact CB-CD1 4.06Å; I159-Y400 HydrophobicContact CB-CE1 3.79Å; I159-Y400 HydrophobicContact CD1-CD1 3.94Å; I159-Y400 HydrophobicContact CD1-CD2 3.76Å; I159-Y400 HydrophobicContact CD1-CE1 4.22Å; I159-Y400 HydrophobicContact CD1-CE2 4.03Å; I159-Y400 HydrophobicContact CD1-CG 3.69Å; I159-Y400 HydrophobicContact CG1-CD1 3.7Å; I159-Y400 HydrophobicContact CG1-CD2 4.44Å; I159-Y400 HydrophobicContact CG1-CE1 3.95Å; I159-Y400 HydrophobicContact CG1-CG 3.95Å; I159-R403 HydrophobicContact CD1-CB 4.49Å; I159-R403 PolarHBondContact O-NH1 3.45Å; I159-R403 VanDerWaalsContact O-NH1 3.08Å
160G86.5Confident95.4Very high27 Ų2743 Ų4328%0.27823%0.229SC..SBendtrans95.6162.8177.700000114.5S157 I158 R403S157-G160 WeakPolarHBondContact O-CA 3.2Å; S157-G160 PolarHBondContact O-N 3.04Å; I158-G160 PolarHBondContact O-N 3.47Å; G160-R403 PolarHBondContact O-NH1 2.82Å; G160-R403 PolarHBondContact O-NH2 2.94Å
161G90.8Very high95.4Very high41 Ų4145.7 Ų45.742%0.42324%0.242SC..SBendtrans73.1-172.4-173.600000112.7E156 S157E156-G161 CarbonylContact C-O 3.41Å; E156-G161 VanDerWaalsContact CA-O 3.25Å; E156-G161 WeakPolarHBondContact CA-O 3.41Å; S157-G161 PolarHBondContact N-O 3.25Å
162S96.2Very high95.4Very high49 Ų4944.6 Ų44.634%0.34323%0.233SC..BIsolated β-bridgetrans-64.4144.5179.9-168.70000111.5W164 H176S162-W164 PolarHBondContact O-N 2.73Å; S162-W164 PolarHBondContact OG-N 3.14Å; S162-H176 PolarHBondContact O-CE1 3.28Å; S162-H176 VanDerWaalsContact O-CE1 3.24Å
163A97.9Very high95.5Very high1 Ų143.8 Ų43.81%0.00823%0.226CC..SBendtrans-78.75.1167.400000113W155 L175 H176W155-A163 HydrophobicContact CB-CB 4.12Å; W155-A163 PolarHBondContact O-N 3.39Å; A163-L175 HydrophobicContact CB-CD1 3.82Å; A163-L175 CarbonylContact O-C 3.29Å; A163-L175 WeakPolarHBondContact O-CA 3.49Å; A163-H176 WeakPolarHBondContact CA-O 3.41Å; A163-H176 PolarHBondContact O-CD2 3.02Å; A163-H176 VanDerWaalsContact O-CD2 3.26Å; A163-H176 PolarHBondContact O-N 3.28Å
164W98.5Very high95.5Very high8 Ų844.1 Ų44.13%0.0323%0.227CC..EExtended strand (participates in β ladder)trans-119.9128.2-176-6399.9000111.6I137 K139 P151 P152 N153 W155 S162 F173 Y174 L175 F225I137-W164 HydrophobicContact CG2-CH2 4.06Å; I137-W164 HydrophobicContact CG2-CZ3 4.35Å; K139-W164 HydrophobicContact CB-CH2 4.09Å; K139-W164 HydrophobicContact CB-CZ3 3.9Å; K139-W164 HydrophobicContact CG-CH2 3.51Å; K139-W164 HydrophobicContact CG-CZ2 4.44Å; K139-W164 HydrophobicContact CG-CZ3 3.77Å; P151-W164 HydrophobicContact CB-CB 3.93Å; P151-W164 HydrophobicContact CB-CG 4.1Å; P151-W164 HydrophobicContact CG-CB 4.33Å; P152-W164 HydrophobicContact CG-CD2 3.57Å; P152-W164 HydrophobicContact CG-CE3 3.91Å; P152-W164 HydrophobicContact CG-CG 4.13Å; P152-W164 HydrophobicContact CG-CH2 3.89Å; P152-W164 HydrophobicContact CG-CZ2 3.55Å; P152-W164 HydrophobicContact CG-CZ3 4.06Å; N153-W164 PolarHBondContact OD1-NE1 2.92Å; W155-W164 HydrophobicContact CE3-CZ2 4.01Å; W155-W164 HydrophobicContact CZ3-CZ2 4.16Å; S162-W164 PolarHBondContact O-N 2.73Å; S162-W164 PolarHBondContact OG-N 3.14Å; W164-F173 HydrophobicContact CB-CB 4.16Å; W164-F173 HydrophobicContact CB-CD1 3.82Å; W164-F173 HydrophobicContact CB-CG 4.26Å; W164-F173 HydrophobicContact CD2-CB 4.44Å; W164-F173 HydrophobicContact CE3-CB 3.8Å; W164-Y174 WeakPolarHBondContact CA-O 3.3Å; W164-L175 HydrophobicContact CD2-CD1 4.21Å; W164-L175 HydrophobicContact CE3-CB 4.09Å; W164-L175 HydrophobicContact CE3-CD1 4.47Å; W164-L175 HydrophobicContact CH2-CB 3.95Å; W164-L175 HydrophobicContact CH2-CD1 4.18Å; W164-L175 HydrophobicContact CZ2-CD1 3.88Å; W164-L175 HydrophobicContact CZ3-CB 3.72Å; W164-L175 HydrophobicContact CZ3-CD1 4.47Å; W164-F225 HydrophobicContact CH2-CD1 4.04Å; W164-F225 HydrophobicContact CH2-CE1 4.05Å; W164-F225 HydrophobicContact CZ2-CD1 4.05Å; W164-F225 HydrophobicContact CZ2-CE1 4.41Å
165E98.3Very high95.6Very high73 Ų7342.1 Ų42.134%0.34122%0.216SC..EExtended strand (participates in β ladder)trans-119.7135.3177.1-178.668.7-146.800110.3F173 Y174 K180E165-F173 CarbonylContact O-C 3.59Å; E165-F173 VanDerWaalsContact O-CA 3.26Å; E165-F173 WeakPolarHBondContact O-CA 3.17Å; E165-Y174 HydrophobicContact CB-CD1 4.24Å; E165-Y174 HydrophobicContact CB-CE1 3.58Å; E165-Y174 HydrophobicContact CB-CE2 4.1Å; E165-Y174 HydrophobicContact CG-CE1 3.64Å; E165-Y174 VanDerWaalsContact CG-OH 3.31Å; E165-Y174 WeakPolarHBondContact CG-OH 3.3Å; E165-Y174 PolarHBondContact N-O 2.72Å; E165-Y174 VanDerWaalsContact N-O 3.11Å; E165-Y174 WeakPolarHBondContact O-CD1 3.48Å; E165-Y174 PolarHBondContact O-N 3.24Å; E165-K180 HydrophobicContact CB-CB 4.43Å; E165-K180 HydrophobicContact CG-CB 4.36Å
166W97.9Very high95.6Very high68 Ų6842.5 Ų42.526%0.25822%0.218SC..EExtended strand (participates in β ladder)trans-78.4129.9-178179.1-107.8000111.5V149 E168 E171 F173V149-W166 HydrophobicContact CG1-CH2 4.43Å; V149-W166 HydrophobicContact CG1-CZ3 4.05Å; W166-E168 PolarHBondContact NE1-OE1 3.45Å; W166-E168 PolarHBondContact NE1-OE2 3.45Å; W166-E171 HydrophobicContact CH2-CB 4.08Å; W166-E171 WeakPolarHBondContact CH2-O 3.5Å; W166-E171 HydrophobicContact CZ2-CB 4.08Å; W166-F173 HydrophobicContact CB-CD1 4.17Å; W166-F173 HydrophobicContact CB-CE1 3.85Å; W166-F173 HydrophobicContact CB-CZ 4.28Å; W166-F173 HydrophobicContact CE3-CD1 4.41Å; W166-F173 AromaticContact CE3-CD2 3.63Å; W166-F173 HydrophobicContact CE3-CD2 3.63Å; W166-F173 HydrophobicContact CE3-CE1 4.29Å; W166-F173 AromaticContact CE3-CE2 3.46Å; W166-F173 HydrophobicContact CE3-CE2 3.46Å; W166-F173 VanDerWaalsContact CE3-CE2 3.46Å; W166-F173 HydrophobicContact CE3-CG 4.11Å; W166-F173 AromaticContact CE3-CZ 3.82Å; W166-F173 HydrophobicContact CE3-CZ 3.82Å; W166-F173 AromaticContact CZ3-CD2 3.98Å; W166-F173 HydrophobicContact CZ3-CD2 3.98Å; W166-F173 AromaticContact CZ3-CE2 3.85Å; W166-F173 HydrophobicContact CZ3-CE2 3.85Å
167C97.8Very high95.7Very high17 Ų1741.6 Ų41.612%0.11521%0.214CC..EExtended strand (participates in β ladder)trans-105.9103.2172.4-179.80000110.6W138 K169 R170 E171 Q172 Y174W138-C167 HydrophobicContact CH2-CB 3.84Å; W138-C167 HydrophobicContact CZ3-CB 3.49Å; W138-C167 VanDerWaalsContact CZ3-CB 3.49Å; C167-K169 PolarHBondContact O-N 2.81Å; C167-R170 HydrophobicContact CB-CB 4.21Å; C167-R170 PolarHBondContact O-N 3.41Å; C167-E171 PolarHBondContact O-N 2.86Å; C167-Q172 PolarHBondContact N-O 3.08Å; C167-Y174 HydrophobicContact CB-CD1 4.35Å
168E95.3Very high95.7Very high143 Ų14342.8 Ų42.867%0.66822%0.219SC*.THydrogen-bonded Turntrans-54.4-37.9-179.8-65.6-64.7172.500113.4W166 R170W166-E168 PolarHBondContact NE1-OE1 3.45Å; W166-E168 PolarHBondContact NE1-OE2 3.45Å; E168-R170 VanDerWaalsContact C-N 3.31Å; E168-R170 PolarHBondContact O-N 3.48Å
169K95.1Very high96Very high179 Ų17941.9 Ų41.978%0.77822%0.215SC*.THydrogen-bonded Turntrans-68.5-30.8-178.8-67.4-179.7-179.4177.40113.1C167C167-K169 PolarHBondContact O-N 2.81Å
170R96.5Very high96.5Very high12 Ų1245.8 Ų45.85%0.04523%0.231CC..THydrogen-bonded Turntrans-99.7-17-176.5-168.5163.7166.9132-4.7112.9S125 C126 R128 A133 D134 W138 C167 E168 Q172S125-R170 PolarHBondContact O-NH1 3.08Å; C126-R170 WeakPolarHBondContact O-CB 3.3Å; R128-R170 HydrophobicContact CG-CG 4.28Å; R128-R170 PolarHBondContact NH2-O 3.46Å; A133-R170 PolarHBondContact O-NH1 3.45Å; A133-R170 PolarHBondContact O-NH2 3.07Å; A133-R170 VanDerWaalsContact O-NH2 3.16Å; D134-R170 IonicContact OD1-NH2 2.81Å; W138-R170 VanDerWaalsContact CD2-CD 3.47Å; W138-R170 HydrophobicContact CE3-CG 4.38Å; W138-R170 HydrophobicContact CZ3-CB 4.33Å; C167-R170 HydrophobicContact CB-CB 4.21Å; C167-R170 PolarHBondContact O-N 3.41Å; E168-R170 VanDerWaalsContact C-N 3.31Å; E168-R170 PolarHBondContact O-N 3.48Å; R170-Q172 VanDerWaalsContact C-N 3.26Å; R170-Q172 HydrophobicContact CG-CB 4.22Å; R170-Q172 HydrophobicContact CG-CG 4.35Å; R170-Q172 PolarHBondContact O-N 3.28Å
171E95.8Very high97Very high145 Ų14546.8 Ų46.868%0.67823%0.228SC*.THydrogen-bonded Turntrans55.239.8-171.7-57.5-178.2168.100112.3W166 C167W166-E171 HydrophobicContact CH2-CB 4.08Å; W166-E171 WeakPolarHBondContact CH2-O 3.5Å; W166-E171 HydrophobicContact CZ2-CB 4.08Å; C167-E171 PolarHBondContact O-N 2.86Å
172Q98Very high97.4Very high17 Ų1744.9 Ų44.98%0.07921%0.209CC..EExtended strand (participates in β ladder)trans-143.1158179.9-69.3-170.2-56.600110.9R128 W138 D140 C167 R170R128-Q172 VanDerWaalsContact NH2-OE1 3.07Å; W138-Q172 HydrophobicContact CE3-CB 3.96Å; D140-Q172 WeakPolarHBondContact OD1-CG 3.4Å; D140-Q172 PolarHBondContact OD1-NE2 3.36Å; C167-Q172 PolarHBondContact N-O 3.08Å; R170-Q172 VanDerWaalsContact C-N 3.26Å; R170-Q172 HydrophobicContact CG-CB 4.22Å; R170-Q172 HydrophobicContact CG-CG 4.35Å; R170-Q172 PolarHBondContact O-N 3.28Å
173F98.6Very high97.5Very high13 Ų1342.5 Ų42.56%0.05719%0.192CC..EExtended strand (participates in β ladder)trans-82.2141.6166.2-70.1-88.6000110.4W138 K139 V149 Q150 P151 W164 E165 W166W138-F173 CarbonylContact C-O 3.55Å; W138-F173 WeakPolarHBondContact CA-O 3.35Å; K139-F173 PolarHBondContact N-O 2.99Å; K139-F173 PolarHBondContact O-N 3.24Å; V149-F173 HydrophobicContact CG1-CE2 3.88Å; Q150-F173 WeakPolarHBondContact O-CE2 3.15Å; P151-F173 HydrophobicContact CG-CE1 4.09Å; P151-F173 HydrophobicContact CG-CZ 4.32Å; W164-F173 HydrophobicContact CB-CB 4.16Å; W164-F173 HydrophobicContact CB-CD1 3.82Å; W164-F173 HydrophobicContact CB-CG 4.26Å; W164-F173 HydrophobicContact CD2-CB 4.44Å; W164-F173 HydrophobicContact CE3-CB 3.8Å; E165-F173 CarbonylContact O-C 3.59Å; E165-F173 VanDerWaalsContact O-CA 3.26Å; E165-F173 WeakPolarHBondContact O-CA 3.17Å; W166-F173 HydrophobicContact CB-CD1 4.17Å; W166-F173 HydrophobicContact CB-CE1 3.85Å; W166-F173 HydrophobicContact CB-CZ 4.28Å; W166-F173 HydrophobicContact CE3-CD1 4.41Å; W166-F173 AromaticContact CE3-CD2 3.63Å; W166-F173 HydrophobicContact CE3-CD2 3.63Å; W166-F173 HydrophobicContact CE3-CE1 4.29Å; W166-F173 AromaticContact CE3-CE2 3.46Å; W166-F173 HydrophobicContact CE3-CE2 3.46Å; W166-F173 VanDerWaalsContact CE3-CE2 3.46Å; W166-F173 HydrophobicContact CE3-CG 4.11Å; W166-F173 AromaticContact CE3-CZ 3.82Å; W166-F173 HydrophobicContact CE3-CZ 3.82Å; W166-F173 AromaticContact CZ3-CD2 3.98Å; W166-F173 HydrophobicContact CZ3-CD2 3.98Å; W166-F173 AromaticContact CZ3-CE2 3.85Å; W166-F173 HydrophobicContact CZ3-CE2 3.85Å
174Y98.7Very high97.6Very high17 Ų1742.5 Ų42.57%0.06719%0.192CC..EExtended strand (participates in β ladder)trans-107148.8162.364.1-83000111F122 I137 W138 W164 E165 C167 H176 K180 P183F122-Y174 HydrophobicContact CE2-CD1 4.36Å; F122-Y174 HydrophobicContact CE2-CD2 4.03Å; F122-Y174 HydrophobicContact CE2-CE2 4.38Å; F122-Y174 HydrophobicContact CE2-CG 4Å; F122-Y174 AromaticContact CZ-CD1 3.97Å; F122-Y174 HydrophobicContact CZ-CD1 3.97Å; F122-Y174 HydrophobicContact CZ-CD2 4.11Å; F122-Y174 AromaticContact CZ-CE1 3.95Å; F122-Y174 HydrophobicContact CZ-CE1 3.95Å; F122-Y174 HydrophobicContact CZ-CE2 4.07Å; F122-Y174 HydrophobicContact CZ-CG 4.04Å; F122-Y174 AromaticContact CZ-CZ 3.98Å; I137-Y174 WeakPolarHBondContact O-CA 3.46Å; W138-Y174 AromaticContact CH2-CD1 3.88Å; W138-Y174 HydrophobicContact CH2-CD1 3.88Å; W138-Y174 HydrophobicContact CH2-CG 4.13Å; W138-Y174 AromaticContact CZ3-CD1 3.75Å; W138-Y174 HydrophobicContact CZ3-CD1 3.75Å; W138-Y174 HydrophobicContact CZ3-CG 4.06Å; W164-Y174 WeakPolarHBondContact CA-O 3.3Å; E165-Y174 HydrophobicContact CB-CD1 4.24Å; E165-Y174 HydrophobicContact CB-CE1 3.58Å; E165-Y174 HydrophobicContact CB-CE2 4.1Å; E165-Y174 HydrophobicContact CG-CE1 3.64Å; E165-Y174 VanDerWaalsContact CG-OH 3.31Å; E165-Y174 WeakPolarHBondContact CG-OH 3.3Å; E165-Y174 PolarHBondContact N-O 2.72Å; E165-Y174 VanDerWaalsContact N-O 3.11Å; E165-Y174 WeakPolarHBondContact O-CD1 3.48Å; E165-Y174 PolarHBondContact O-N 3.24Å; C167-Y174 HydrophobicContact CB-CD1 4.35Å; Y174-H176 HydrophobicContact CE2-CB 4.33Å; Y174-K180 WeakPolarHBondContact CE2-O 3.29Å; Y174-K180 PolarHBondContact OH-O 3.27Å; Y174-P183 HydrophobicContact CD2-CB 3.7Å; Y174-P183 HydrophobicContact CE2-CB 3.93Å
175L98.8Very high97.6Very high2 Ų242.1 Ų42.11%0.0119%0.19CC..EExtended strand (participates in β ladder)trans-80.3138175.2-176.369.1000110.8I137 W155 A163 W164 D184 K221I137-L175 HydrophobicContact CB-CB 4.01Å; I137-L175 HydrophobicContact CB-CD2 4.44Å; I137-L175 HydrophobicContact CD1-CD2 3.94Å; I137-L175 HydrophobicContact CG2-CB 4.02Å; I137-L175 HydrophobicContact CG2-CD2 4.29Å; I137-L175 PolarHBondContact O-N 3.05Å; W155-L175 HydrophobicContact CE3-CD1 3.78Å; W155-L175 HydrophobicContact CE3-CD2 4.45Å; W155-L175 HydrophobicContact CZ3-CD1 4.21Å; W155-L175 HydrophobicContact CZ3-CD2 4.1Å; A163-L175 HydrophobicContact CB-CD1 3.82Å; A163-L175 CarbonylContact O-C 3.29Å; A163-L175 WeakPolarHBondContact O-CA 3.49Å; W164-L175 HydrophobicContact CD2-CD1 4.21Å; W164-L175 HydrophobicContact CE3-CB 4.09Å; W164-L175 HydrophobicContact CE3-CD1 4.47Å; W164-L175 HydrophobicContact CH2-CB 3.95Å; W164-L175 HydrophobicContact CH2-CD1 4.18Å; W164-L175 HydrophobicContact CZ2-CD1 3.88Å; W164-L175 HydrophobicContact CZ3-CB 3.72Å; W164-L175 HydrophobicContact CZ3-CD1 4.47Å; L175-D184 HydrophobicContact CB-CB 4.32Å; L175-D184 HydrophobicContact CD2-CB 4.1Å; L175-D184 HydrophobicContact CG-CB 4.18Å; L175-D184 PolarHBondContact O-N 2.73Å; L175-K221 HydrophobicContact CD2-CD 3.73Å; L175-K221 HydrophobicContact CD2-CG 3.99Å
176H98.6Very high97.6Very high10 Ų1040 Ų405%0.04618%0.182CC..  trans-139.8115167.561.889.4000110S162 A163 Y174 F178 L179 Q182S162-H176 PolarHBondContact O-CE1 3.28Å; S162-H176 VanDerWaalsContact O-CE1 3.24Å; A163-H176 WeakPolarHBondContact CA-O 3.41Å; A163-H176 PolarHBondContact O-CD2 3.02Å; A163-H176 VanDerWaalsContact O-CD2 3.26Å; A163-H176 PolarHBondContact O-N 3.28Å; Y174-H176 HydrophobicContact CE2-CB 4.33Å; H176-F178 VanDerWaalsContact C-N 3.3Å; H176-F178 PolarHBondContact ND1-O 3.31Å; H176-F178 VanDerWaalsContact ND1-O 3.09Å; H176-F178 PolarHBondContact O-N 2.95Å; H176-L179 WeakPolarHBondContact CB-O 3.45Å; H176-Q182 WeakPolarHBondContact CB-O 3.36Å
177T97.8Very high97.6Very high5 Ų537 Ų373%0.03117%0.17CC..SBendtrans-69.6-31.9-179.5-69.10000111.9S157 I158 D184 Y218S157-T177 WeakPolarHBondContact CA-O 3.32Å; S157-T177 PolarHBondContact OG-O 2.88Å; I158-T177 HydrophobicContact CG1-CG2 3.94Å; I158-T177 PolarHBondContact N-O 2.77Å; T177-D184 PolarHBondContact N-OD1 3.29Å; T177-D184 PolarHBondContact OG1-OD1 3.2Å; T177-D184 PolarHBondContact OG1-OD2 2.89Å; T177-Y218 HydrophobicContact CG2-CD1 3.75Å; T177-Y218 HydrophobicContact CG2-CD2 4.06Å; T177-Y218 HydrophobicContact CG2-CE1 4.11Å; T177-Y218 HydrophobicContact CG2-CE2 4.39Å; T177-Y218 HydrophobicContact CG2-CG 3.72Å
178F96.2Very high97.5Very high26 Ų2639.9 Ų39.911%0.11418%0.179CC..SBendtrans-113.3-123.6-178.3-59.7-77.5000109.9H114 S157 I158 H176 A215 Y218 Y400H114-F178 AromaticContact CE1-CD2 3.38Å; H114-F178 WeakPolarHBondContact CE1-CD2 3.43Å; H114-F178 AromaticContact CE1-CE2 3.63Å; H114-F178 AromaticContact ND1-CD2 3.68Å; H114-F178 AromaticContact ND1-CE2 3.97Å; S157-F178 PolarHBondContact OG-O 3.17Å; I158-F178 HydrophobicContact CB-CD1 3.91Å; I158-F178 HydrophobicContact CB-CE1 4.09Å; I158-F178 HydrophobicContact CG1-CD1 4.16Å; I158-F178 HydrophobicContact CG1-CE1 4Å; I158-F178 HydrophobicContact CG2-CD1 4.32Å; I158-F178 HydrophobicContact CG2-CE1 4.23Å; H176-F178 VanDerWaalsContact C-N 3.3Å; H176-F178 PolarHBondContact ND1-O 3.31Å; H176-F178 VanDerWaalsContact ND1-O 3.09Å; H176-F178 PolarHBondContact O-N 2.95Å; F178-A215 HydrophobicContact CE2-CB 3.74Å; F178-A215 HydrophobicContact CZ-CB 3.9Å; F178-Y218 HydrophobicContact CE1-CE2 4.5Å; F178-Y218 HydrophobicContact CE2-CD2 4.29Å; F178-Y218 AromaticContact CZ-CD2 3.95Å; F178-Y218 HydrophobicContact CZ-CD2 3.95Å; F178-Y218 AromaticContact CZ-CE2 3.86Å; F178-Y218 HydrophobicContact CZ-CE2 3.86Å; F178-Y400 WeakPolarHBondContact CD1-OH 3.32Å
179L96.2Very high97.6Very high13 Ų1334.5 Ų34.57%0.06816%0.155CC..  trans-65.6153176.7-59.4173.9000111V70 D71 I159 H176 E181 Q182 P399V70-L179 HydrophobicContact CG1-CD1 3.84Å; D71-L179 HydrophobicContact CB-CD1 3.89Å; I159-L179 HydrophobicContact CD1-CD2 3.35Å; I159-L179 HydrophobicContact CG2-CD2 4.16Å; H176-L179 WeakPolarHBondContact CB-O 3.45Å; L179-E181 PolarHBondContact O-N 3.49Å; L179-Q182 HydrophobicContact CB-CB 4.42Å; L179-Q182 HydrophobicContact CB-CG 4.24Å; L179-Q182 WeakPolarHBondContact O-CA 3.41Å; L179-Q182 WeakPolarHBondContact O-CB 3.45Å; L179-Q182 PolarHBondContact O-N 3.44Å; L179-P399 HydrophobicContact CD1-CB 4.09Å; L179-P399 HydrophobicContact CD1-CG 3.84Å; L179-P399 HydrophobicContact CD2-CB 4.02Å; L179-P399 HydrophobicContact CD2-CG 4.42Å
180K96.7Very high97.7Very high95 Ų9529 Ų2941%0.41314%0.139SC..THydrogen-bonded Turntrans-62.7-26.8173.666.5179-176.1178.70112E165 Y174 Q182E165-K180 HydrophobicContact CB-CB 4.43Å; E165-K180 HydrophobicContact CG-CB 4.36Å; Y174-K180 WeakPolarHBondContact CE2-O 3.29Å; Y174-K180 PolarHBondContact OH-O 3.27Å; K180-Q182 PolarHBondContact O-N 2.92Å
181E98Very high97.7Very high48 Ų4830.5 Ų30.522%0.22415%0.148CC..THydrogen-bonded Turntrans-71.3-1171.8-62.777.5-168.700113.1V70 S116 D117 L179 P183V70-E181 HydrophobicContact CG1-CB 4.28Å; V70-E181 HydrophobicContact CG1-CG 4.24Å; V70-E181 HydrophobicContact CG2-CB 4.48Å; V70-E181 HydrophobicContact CG2-CG 4.38Å; S116-E181 CarbonylContact C-O 3.22Å; S116-E181 VanDerWaalsContact CA-O 3.29Å; S116-E181 WeakPolarHBondContact CA-O 3.41Å; D117-E181 PolarHBondContact N-O 3.15Å; L179-E181 PolarHBondContact O-N 3.49Å; E181-P183 WeakPolarHBondContact O-CD 3.38Å
182Q98.6Very high97.9Very high1 Ų123.7 Ų23.71%0.00512%0.116CC..SBendtrans-118.666.1179.4-71.2169.6-45.200111.8D71 D75 H114 T115 H176 L179 K180D71-Q182 PolarHBondContact OD2-NE2 3.49Å; D71-Q182 VanDerWaalsContact OD2-NE2 3.15Å; D75-Q182 HydrophobicContact CB-CG 4.03Å; H114-Q182 HydrophobicContact CB-CB 4.31Å; H114-Q182 PolarHBondContact NE2-NE2 3.19Å; T115-Q182 VanDerWaalsContact O-CA 3.28Å; T115-Q182 WeakPolarHBondContact O-CA 3.46Å; H176-Q182 WeakPolarHBondContact CB-O 3.36Å; L179-Q182 HydrophobicContact CB-CB 4.42Å; L179-Q182 HydrophobicContact CB-CG 4.24Å; L179-Q182 WeakPolarHBondContact O-CA 3.41Å; L179-Q182 WeakPolarHBondContact O-CB 3.45Å; L179-Q182 PolarHBondContact O-N 3.44Å; K180-Q182 PolarHBondContact O-N 2.92Å
183P98.8Very high97.9Very high0 Ų026.5 Ų26.50%013%0.128CC..PPolyproline II helixtrans-64.4135.217927.4-37.9000113H114 T115 D117 F122 Y136 Y174 E181H114-P183 VanDerWaalsContact CA-O 3.27Å; H114-P183 WeakPolarHBondContact CA-O 3.42Å; H114-P183 WeakPolarHBondContact CB-O 3.4Å; T115-P183 PolarHBondContact N-O 3.42Å; T115-P183 VanDerWaalsContact O-CD 3.23Å; T115-P183 WeakPolarHBondContact O-CD 3.38Å; D117-P183 HydrophobicContact CB-CG 4.43Å; F122-P183 HydrophobicContact CB-CG 4.35Å; F122-P183 HydrophobicContact CD1-CG 4.37Å; F122-P183 HydrophobicContact CD2-CB 3.58Å; F122-P183 HydrophobicContact CD2-CG 3.44Å; F122-P183 VanDerWaalsContact CD2-CG 3.44Å; F122-P183 HydrophobicContact CE2-CB 3.43Å; F122-P183 VanDerWaalsContact CE2-CB 3.43Å; F122-P183 HydrophobicContact CE2-CG 3.69Å; F122-P183 HydrophobicContact CG-CB 4.42Å; F122-P183 HydrophobicContact CG-CG 3.8Å; F122-P183 HydrophobicContact CZ-CB 4.16Å; F122-P183 HydrophobicContact CZ-CG 4.22Å; Y136-P183 HydrophobicContact CD1-CB 3.72Å; Y136-P183 HydrophobicContact CD1-CG 4.07Å; Y136-P183 HydrophobicContact CE1-CB 4.03Å; Y136-P183 HydrophobicContact CE1-CG 3.84Å; Y136-P183 WeakPolarHBondContact CE1-O 3.37Å; Y174-P183 HydrophobicContact CD2-CB 3.7Å; Y174-P183 HydrophobicContact CE2-CB 3.93Å; E181-P183 WeakPolarHBondContact O-CD 3.38Å
184D98.9Very high97.9Very high0 Ų031.9 Ų31.90%015%0.148CC..BIsolated β-bridgetrans-76.1132.4-175.6-79.723.8000112.6N113 Y136 I137 L175 T177 K221N113-D184 PolarHBondContact ND2-OD1 2.96Å; N113-D184 WeakPolarHBondContact O-CA 3.35Å; Y136-D184 WeakPolarHBondContact CA-O 3.48Å; Y136-D184 WeakPolarHBondContact CD1-O 3.19Å; I137-D184 PolarHBondContact N-O 3.31Å; L175-D184 HydrophobicContact CB-CB 4.32Å; L175-D184 HydrophobicContact CD2-CB 4.1Å; L175-D184 HydrophobicContact CG-CB 4.18Å; L175-D184 PolarHBondContact O-N 2.73Å; T177-D184 PolarHBondContact N-OD1 3.29Å; T177-D184 PolarHBondContact OG1-OD1 3.2Å; T177-D184 PolarHBondContact OG1-OD2 2.89Å; D184-K221 WeakPolarHBondContact OD2-CE 3.31Å; D184-K221 IonicContact OD2-NZ 3.84Å; D184-K221 PolarHBondContact OD2-NZ 2.71Å
185L98.8Very high97.8Very high0 Ų033.1 Ų33.10%015%0.154CC..BIsolated β-bridgetrans-70.8145.6175.4-75.6172.5000111.6P112 N113 T115 W121 F135 Y136 Y187 V192 M196P112-L185 WeakPolarHBondContact O-CD1 3.42Å; N113-L185 PolarHBondContact O-N 3.27Å; T115-L185 HydrophobicContact CG2-CD1 3.88Å; T115-L185 HydrophobicContact CG2-CD2 3.99Å; T115-L185 HydrophobicContact CG2-CG 4.01Å; W121-L185 HydrophobicContact CE3-CD2 4.26Å; F135-L185 WeakPolarHBondContact O-CA 3.37Å; F135-L185 WeakPolarHBondContact O-CD2 3.46Å; Y136-L185 HydrophobicContact CD1-CD2 4.24Å; Y136-L185 HydrophobicContact CE1-CD2 3.75Å; Y136-L185 HydrophobicContact CE1-CG 4.3Å; Y136-L185 HydrophobicContact CE2-CD2 4.33Å; L185-Y187 HydrophobicContact CB-CD2 4.45Å; L185-Y187 HydrophobicContact CB-CE2 4.14Å; L185-V192 HydrophobicContact CB-CG1 4.03Å; L185-V192 HydrophobicContact CD1-CG1 4.29Å; L185-V192 HydrophobicContact CD2-CG1 4.19Å; L185-V192 HydrophobicContact CG-CG1 4.41Å; L185-M196 HydrophobicContact CD1-CE 3.94Å
186N98.5Very high97.8Very high30 Ų3033.1 Ų33.116%0.1615%0.154CC..  trans-96.590.5176.8178.517.6000111.2D134 F135 I137 R188 N189D134-N186 WeakPolarHBondContact O-CB 3.41Å; D134-N186 PolarHBondContact O-ND2 3.12Å; D134-N186 VanDerWaalsContact O-ND2 3.15Å; F135-N186 PolarHBondContact O-N 2.94Å; I137-N186 HydrophobicContact CG1-CB 3.78Å; N186-R188 PolarHBondContact O-N 3.38Å; N186-R188 VanDerWaalsContact O-N 3.14Å; N186-R188 WeakPolarHBondContact OD1-CB 3.27Å; N186-R188 PolarHBondContact OD1-N 2.58Å; N186-N189 VanDerWaalsContact O-CB 3.3Å; N186-N189 WeakPolarHBondContact O-CB 2.95Å; N186-N189 PolarHBondContact O-N 3.07Å
187Y98Very high97.8Very high3 Ų335 Ų351%0.01216%0.163CC..THydrogen-bonded Turntrans-70.1-3.4178.4-82-76.2000115.3P112 L185 V192 K193 M196 V219 M220 L263 W267P112-Y187 HydrophobicContact CB-CE2 4.46Å; P112-Y187 WeakPolarHBondContact CB-OH 3.45Å; P112-Y187 WeakPolarHBondContact O-CE2 3.45Å; P112-Y187 PolarHBondContact O-OH 2.67Å; L185-Y187 HydrophobicContact CB-CD2 4.45Å; L185-Y187 HydrophobicContact CB-CE2 4.14Å; Y187-V192 HydrophobicContact CD1-CG1 3.99Å; Y187-V192 HydrophobicContact CE1-CG1 3.91Å; Y187-V192 HydrophobicContact CG-CG1 4.37Å; Y187-K193 HydrophobicContact CD1-CG 3.93Å; Y187-K193 WeakPolarHBondContact O-CE 3.05Å; Y187-M196 HydrophobicContact CE1-CB 4.38Å; Y187-M196 WeakPolarHBondContact OH-CG 3.4Å; Y187-V219 HydrophobicContact CD2-CB 4.14Å; Y187-V219 HydrophobicContact CE2-CB 4.2Å; Y187-V219 HydrophobicContact CE2-CG1 4.43Å; Y187-M220 VanDerWaalsContact CB-SD 3.57Å; Y187-L263 HydrophobicContact CD1-CD1 3.99Å; Y187-L263 HydrophobicContact CD1-CD2 3.61Å; Y187-L263 HydrophobicContact CD1-CG 4.45Å; Y187-L263 HydrophobicContact CD2-CD2 4.04Å; Y187-L263 HydrophobicContact CE1-CD1 4.41Å; Y187-L263 HydrophobicContact CE1-CD2 4.05Å; Y187-L263 HydrophobicContact CE2-CD2 4.43Å; Y187-L263 HydrophobicContact CG-CD2 3.6Å; Y187-W267 AromaticContact CE1-CZ2 3.89Å; Y187-W267 HydrophobicContact CE1-CZ2 3.89Å; Y187-W267 AromaticContact CZ-CZ2 3.95Å
188R96Very high97.9Very high79 Ų7938.9 Ų38.930%0.29818%0.181SC..THydrogen-bonded Turntrans-74-21.5166.4-65.2-171.2170.378.410.8112.1N186 S190 M220 K221 E223 E259N186-R188 PolarHBondContact O-N 3.38Å; N186-R188 VanDerWaalsContact O-N 3.14Å; N186-R188 WeakPolarHBondContact OD1-CB 3.27Å; N186-R188 PolarHBondContact OD1-N 2.58Å; R188-S190 PolarHBondContact O-N 2.99Å; R188-M220 HydrophobicContact CG-CE 4.23Å; R188-K221 PolarHBondContact NH1-O 2.51Å; R188-K221 PolarHBondContact NH2-O 3.24Å; R188-E223 IonicContact CZ-OE1 3.47Å; R188-E223 VanDerWaalsContact NE-CG 3.28Å; R188-E223 IonicContact NE-OE1 3.9Å; R188-E223 PolarHBondContact NE-OE1 3.5Å; R188-E223 IonicContact NH2-OE1 3.52Å; R188-E259 IonicContact NH2-OE1 2.75Å; R188-E259 PolarHBondContact NH2-OE1 3.18Å
189N97.2Very high98Very high30 Ų3037.7 Ų37.716%0.1618%0.175CC..SBendtrans-75.1116.5168.7-172.3-21.4000109.7D134 N186 D191 V192 K193D134-N189 WeakPolarHBondContact O-CB 3.38Å; D134-N189 PolarHBondContact O-ND2 2.88Å; D134-N189 VanDerWaalsContact O-ND2 3.14Å; N186-N189 VanDerWaalsContact O-CB 3.3Å; N186-N189 WeakPolarHBondContact O-CB 2.95Å; N186-N189 PolarHBondContact O-N 3.07Å; N189-D191 PolarHBondContact O-N 3.23Å; N189-D191 VanDerWaalsContact O-N 3.16Å; N189-D191 VanDerWaalsContact OD1-CB 3.31Å; N189-D191 WeakPolarHBondContact OD1-CB 3.5Å; N189-D191 PolarHBondContact OD1-N 3.01Å; N189-V192 HydrophobicContact CB-CB 4.48Å; N189-V192 HydrophobicContact CB-CG2 3.97Å; N189-V192 WeakPolarHBondContact O-CB 3.4Å; N189-V192 PolarHBondContact O-N 2.9Å; N189-K193 PolarHBondContact O-N 2.8Å
190S96.6Very high98.1Very high64 Ų6437 Ų3745%0.44817%0.172SC..Hα-helixtrans-61.8-23.2-179.972.70000113.4R188 K193 R194R188-S190 PolarHBondContact O-N 2.99Å; S190-K193 PolarHBondContact O-N 3.25Å; S190-R194 WeakPolarHBondContact O-CG 3.5Å; S190-R194 PolarHBondContact O-N 3.14Å; S190-R194 VanDerWaalsContact O-N 3.12Å; S190-R194 PolarHBondContact O-NH1 3.28Å; S190-R194 PolarHBondContact OG-NH1 2.95Å; S190-R194 VanDerWaalsContact OG-NH1 3.09Å
191D98Very high98.2Very high43 Ų4333.6 Ų33.623%0.2316%0.158CC..Hα-helixtrans-73.2-35.7180-67.116.2000110.9F135 N189 K193 R194 E195F135-D191 HydrophobicContact CE2-CB 3.71Å; F135-D191 HydrophobicContact CZ-CB 3.88Å; N189-D191 PolarHBondContact O-N 3.23Å; N189-D191 VanDerWaalsContact O-N 3.16Å; N189-D191 VanDerWaalsContact OD1-CB 3.31Å; N189-D191 WeakPolarHBondContact OD1-CB 3.5Å; N189-D191 PolarHBondContact OD1-N 3.01Å; D191-K193 VanDerWaalsContact C-N 3.35Å; D191-R194 PolarHBondContact O-N 3.08Å; D191-R194 IonicContact OD1-CZ 3.1Å; D191-R194 IonicContact OD1-NH1 2.81Å; D191-R194 PolarHBondContact OD1-NH1 3.26Å; D191-R194 IonicContact OD1-NH2 2.64Å; D191-R194 PolarHBondContact OD1-NH2 3.42Å; D191-R194 IonicContact OD2-NH2 3.42Å; D191-R194 PolarHBondContact OD2-NH2 2.92Å; D191-E195 WeakPolarHBondContact O-CB 3.36Å; D191-E195 WeakPolarHBondContact O-CG 3.44Å; D191-E195 PolarHBondContact O-N 3.41Å
192V98.5Very high98.3Very high1 Ų133.7 Ų33.71%0.00616%0.158CC..Hα-helixtrans-62.5-43.6172.8174.90000110.4F135 L185 Y187 N189 E195 M196F135-V192 HydrophobicContact CB-CG2 4.07Å; F135-V192 HydrophobicContact CD1-CG2 3.92Å; F135-V192 HydrophobicContact CD2-CG2 4.02Å; F135-V192 HydrophobicContact CE1-CG2 4.35Å; F135-V192 HydrophobicContact CE2-CG2 4.43Å; F135-V192 HydrophobicContact CG-CG2 3.75Å; L185-V192 HydrophobicContact CB-CG1 4.03Å; L185-V192 HydrophobicContact CD1-CG1 4.29Å; L185-V192 HydrophobicContact CD2-CG1 4.19Å; L185-V192 HydrophobicContact CG-CG1 4.41Å; Y187-V192 HydrophobicContact CD1-CG1 3.99Å; Y187-V192 HydrophobicContact CE1-CG1 3.91Å; Y187-V192 HydrophobicContact CG-CG1 4.37Å; N189-V192 HydrophobicContact CB-CB 4.48Å; N189-V192 HydrophobicContact CB-CG2 3.97Å; N189-V192 WeakPolarHBondContact O-CB 3.4Å; N189-V192 PolarHBondContact O-N 2.9Å; V192-E195 PolarHBondContact O-N 2.78Å; V192-M196 WeakPolarHBondContact O-CB 3.37Å; V192-M196 PolarHBondContact O-N 3.15Å
193K98.1Very high98.3Very high77 Ų7733.7 Ų33.734%0.33516%0.158SC..Hα-helixtrans-56.5-52.3174.5-65.1-174.3-172.1-166.40111Y187 N189 S190 D191 M196 E197 L263Y187-K193 HydrophobicContact CD1-CG 3.93Å; Y187-K193 WeakPolarHBondContact O-CE 3.05Å; N189-K193 PolarHBondContact O-N 2.8Å; S190-K193 PolarHBondContact O-N 3.25Å; D191-K193 VanDerWaalsContact C-N 3.35Å; K193-M196 PolarHBondContact O-N 3.44Å; K193-E197 WeakPolarHBondContact O-CG 3.24Å; K193-E197 PolarHBondContact O-N 3.12Å; K193-L263 HydrophobicContact CD-CD1 4.18Å; K193-L263 HydrophobicContact CG-CD1 4.11Å
194R98.1Very high98.3Very high125 Ų12533.8 Ų33.847%0.47216%0.159SC..Hα-helixtrans-63.3-43.1-178.2-68.2-167.5-46.2-87.74.1112.8S190 D191 M196 E197 E198S190-R194 WeakPolarHBondContact O-CG 3.5Å; S190-R194 PolarHBondContact O-N 3.14Å; S190-R194 VanDerWaalsContact O-N 3.12Å; S190-R194 PolarHBondContact O-NH1 3.28Å; S190-R194 PolarHBondContact OG-NH1 2.95Å; S190-R194 VanDerWaalsContact OG-NH1 3.09Å; D191-R194 PolarHBondContact O-N 3.08Å; D191-R194 IonicContact OD1-CZ 3.1Å; D191-R194 IonicContact OD1-NH1 2.81Å; D191-R194 PolarHBondContact OD1-NH1 3.26Å; D191-R194 IonicContact OD1-NH2 2.64Å; D191-R194 PolarHBondContact OD1-NH2 3.42Å; D191-R194 IonicContact OD2-NH2 3.42Å; D191-R194 PolarHBondContact OD2-NH2 2.92Å; R194-M196 VanDerWaalsContact C-N 3.35Å; R194-E197 PolarHBondContact O-N 3.49Å; R194-E198 PolarHBondContact O-N 3.01Å
195E98.3Very high98.2Very high44 Ų4440.4 Ų40.421%0.20618%0.184CC..Hα-helixtrans-64.3-40.3178.7-73.3-71.5167.800111.6R80 W121 K131 F135 D191 V192 E198 I199R80-E195 IonicContact CZ-OE2 3.9Å; R80-E195 IonicContact NH2-OE2 3.78Å; R80-E195 PolarHBondContact NH2-OE2 2.83Å; W121-E195 HydrophobicContact CH2-CB 3.7Å; W121-E195 HydrophobicContact CH2-CG 4.46Å; W121-E195 HydrophobicContact CZ2-CB 3.76Å; W121-E195 HydrophobicContact CZ2-CG 4.05Å; K131-E195 IonicContact NZ-OE1 3.83Å; F135-E195 HydrophobicContact CE1-CG 4.26Å; F135-E195 HydrophobicContact CZ-CG 4.32Å; D191-E195 WeakPolarHBondContact O-CB 3.36Å; D191-E195 WeakPolarHBondContact O-CG 3.44Å; D191-E195 PolarHBondContact O-N 3.41Å; V192-E195 PolarHBondContact O-N 2.78Å; E195-E198 PolarHBondContact O-N 3.24Å; E195-I199 WeakPolarHBondContact O-CD1 3.41Å; E195-I199 WeakPolarHBondContact O-CG1 3.15Å; E195-I199 PolarHBondContact O-N 3.48Å
196M98.7Very high98.2Very high1 Ų142.2 Ų42.21%0.00519%0.193CC..Hα-helixtrans-66.3-40.6175.4-170.259.762.900112.2Y79 M110 P112 L185 Y187 V192 K193 R194 E198 I199 F200Y79-M196 HydrophobicContact CE1-CE 4.39Å; Y79-M196 HydrophobicContact CE2-CE 4.46Å; M110-M196 HydrophobicContact SD-SD 4.28Å; P112-M196 HydrophobicContact CB-CE 4.42Å; P112-M196 HydrophobicContact CB-SD 4.49Å; L185-M196 HydrophobicContact CD1-CE 3.94Å; Y187-M196 HydrophobicContact CE1-CB 4.38Å; Y187-M196 WeakPolarHBondContact OH-CG 3.4Å; V192-M196 WeakPolarHBondContact O-CB 3.37Å; V192-M196 PolarHBondContact O-N 3.15Å; K193-M196 PolarHBondContact O-N 3.44Å; R194-M196 VanDerWaalsContact C-N 3.35Å; M196-E198 VanDerWaalsContact C-N 3.34Å; M196-E198 PolarHBondContact O-N 2.97Å; M196-I199 HydrophobicContact CE-CD1 4.45Å; M196-I199 WeakPolarHBondContact O-CB 3.38Å; M196-I199 PolarHBondContact O-N 3.44Å; M196-I199 HydrophobicContact SD-CB 4.45Å; M196-I199 HydrophobicContact SD-CD1 4.3Å; M196-I199 HydrophobicContact SD-CG2 4.43Å; M196-F200 HydrophobicContact CG-CD2 4.22Å; M196-F200 HydrophobicContact CG-CE2 3.78Å; M196-F200 WeakPolarHBondContact O-CD2 3.41Å; M196-F200 PolarHBondContact O-N 2.79Å; M196-F200 HydrophobicContact SD-CE2 4.43Å
197E98.7Very high98.2Very high49 Ų4941.4 Ų41.423%0.22919%0.192CC..Hα-helixtrans-60.6-41.2173.5-72.5176.7170.800112K193 R194 I199 F200 L201 S266 L270K193-E197 WeakPolarHBondContact O-CG 3.24Å; K193-E197 PolarHBondContact O-N 3.12Å; R194-E197 PolarHBondContact O-N 3.49Å; E197-I199 VanDerWaalsContact C-N 3.33Å; E197-I199 PolarHBondContact O-N 2.77Å; E197-F200 PolarHBondContact O-N 3.33Å; E197-L201 WeakPolarHBondContact O-CG 3.36Å; E197-L201 PolarHBondContact O-N 3.41Å; E197-S266 PolarHBondContact OE1-OG 2.87Å; E197-S266 VanDerWaalsContact OE1-OG 3.07Å; E197-L270 HydrophobicContact CB-CD2 3.76Å; E197-L270 HydrophobicContact CG-CD2 3.93Å
198E98.7Very high98.2Very high88 Ų8841.3 Ų41.341%0.41119%0.192SC..Hα-helixtrans-67.5-31.1174.4-76.7-57.4149.900113.6R194 E195 M196 L201 H202 R205R194-E198 PolarHBondContact O-N 3.01Å; E195-E198 PolarHBondContact O-N 3.24Å; M196-E198 VanDerWaalsContact C-N 3.34Å; M196-E198 PolarHBondContact O-N 2.97Å; E198-L201 PolarHBondContact O-N 3.46Å; E198-H202 WeakPolarHBondContact O-CB 3.04Å; E198-H202 PolarHBondContact O-N 2.86Å; E198-R205 IonicContact OE2-CZ 2.88Å; E198-R205 IonicContact OE2-NH1 2.86Å; E198-R205 IonicContact OE2-NH2 2.63Å; E198-R205 PolarHBondContact OE2-NH2 3.04Å
199I98.8Very high98.4Very high0 Ų037.9 Ų37.90%018%0.179CC..Hα-helixtrans-64.2-47171.8-74.3160.1000110.4Y79 M110 W121 E195 M196 E197 L201 H202 W203Y79-I199 HydrophobicContact CD1-CD1 4.23Å; Y79-I199 HydrophobicContact CD1-CG2 3.83Å; Y79-I199 HydrophobicContact CD2-CD1 3.71Å; Y79-I199 HydrophobicContact CG-CD1 3.55Å; Y79-I199 HydrophobicContact CG-CG1 4.21Å; Y79-I199 HydrophobicContact CG-CG2 4.01Å; M110-I199 HydrophobicContact CE-CG2 3.7Å; M110-I199 HydrophobicContact SD-CG2 3.92Å; W121-I199 HydrophobicContact CH2-CD1 3.68Å; W121-I199 HydrophobicContact CZ2-CD1 4.47Å; E195-I199 WeakPolarHBondContact O-CD1 3.41Å; E195-I199 WeakPolarHBondContact O-CG1 3.15Å; E195-I199 PolarHBondContact O-N 3.48Å; M196-I199 HydrophobicContact CE-CD1 4.45Å; M196-I199 WeakPolarHBondContact O-CB 3.38Å; M196-I199 PolarHBondContact O-N 3.44Å; M196-I199 HydrophobicContact SD-CB 4.45Å; M196-I199 HydrophobicContact SD-CD1 4.3Å; M196-I199 HydrophobicContact SD-CG2 4.43Å; E197-I199 VanDerWaalsContact C-N 3.33Å; E197-I199 PolarHBondContact O-N 2.77Å; I199-L201 VanDerWaalsContact C-N 3.34Å; I199-L201 PolarHBondContact O-N 2.95Å; I199-H202 WeakPolarHBondContact O-CB 3.39Å; I199-H202 PolarHBondContact O-N 3.2Å; I199-W203 PolarHBondContact O-N 3.42Å
200F98.8Very high98.4Very high0 Ų036.4 Ų36.40%017%0.171CC..Hα-helixtrans-57.4-49173.7-74.5-63.9000111.4M110 M196 E197 H202 W203 L204 F211 W267 L270 F271M110-F200 HydrophobicContact CB-CE1 3.83Å; M110-F200 HydrophobicContact CB-CZ 4.38Å; M110-F200 HydrophobicContact CE-CD1 4Å; M110-F200 HydrophobicContact CE-CE1 4.13Å; M110-F200 HydrophobicContact CG-CD1 4.24Å; M110-F200 HydrophobicContact CG-CE1 3.44Å; M110-F200 VanDerWaalsContact CG-CE1 3.44Å; M110-F200 HydrophobicContact CG-CZ 3.7Å; M110-F200 HydrophobicContact SD-CE1 4.49Å; M196-F200 HydrophobicContact CG-CD2 4.22Å; M196-F200 HydrophobicContact CG-CE2 3.78Å; M196-F200 WeakPolarHBondContact O-CD2 3.41Å; M196-F200 PolarHBondContact O-N 2.79Å; M196-F200 HydrophobicContact SD-CE2 4.43Å; E197-F200 PolarHBondContact O-N 3.33Å; F200-H202 VanDerWaalsContact C-N 3.29Å; F200-H202 PolarHBondContact O-N 3.5Å; F200-W203 PolarHBondContact O-N 2.87Å; F200-L204 WeakPolarHBondContact O-CG 3.15Å; F200-L204 PolarHBondContact O-N 3.28Å; F200-F211 HydrophobicContact CB-CE2 4.27Å; F200-F211 HydrophobicContact CB-CZ 4.38Å; F200-F211 AromaticContact CD1-CD1 3.98Å; F200-F211 HydrophobicContact CD1-CD1 3.98Å; F200-F211 AromaticContact CD1-CD2 3.62Å; F200-F211 HydrophobicContact CD1-CD2 3.62Å; F200-F211 AromaticContact CD1-CE1 3.99Å; F200-F211 HydrophobicContact CD1-CE1 3.99Å; F200-F211 AromaticContact CD1-CE2 3.62Å; F200-F211 HydrophobicContact CD1-CE2 3.62Å; F200-F211 AromaticContact CD1-CG 3.8Å; F200-F211 HydrophobicContact CD1-CG 3.8Å; F200-F211 AromaticContact CD1-CZ 3.82Å; F200-F211 HydrophobicContact CD1-CZ 3.82Å; F200-F211 HydrophobicContact CE1-CB 4.19Å; F200-F211 HydrophobicContact CE1-CD1 4.17Å; F200-F211 HydrophobicContact CE1-CD2 4Å; F200-F211 HydrophobicContact CE1-CE2 4.45Å; F200-F211 AromaticContact CE1-CG 3.85Å; F200-F211 HydrophobicContact CE1-CG 3.85Å; F200-F211 HydrophobicContact CG-CE2 4.4Å; F200-W267 HydrophobicContact CD2-CG 4.48Å; F200-W267 HydrophobicContact CE2-CB 4.41Å; F200-W267 AromaticContact CE2-CD1 3.9Å; F200-W267 AromaticContact CE2-CD2 3.91Å; F200-W267 HydrophobicContact CE2-CD2 3.91Å; F200-W267 AromaticContact CE2-CG 3.83Å; F200-W267 HydrophobicContact CE2-CG 3.83Å; F200-W267 HydrophobicContact CZ-CD2 4.32Å; F200-W267 HydrophobicContact CZ-CG 4.47Å; F200-L270 HydrophobicContact CB-CD2 4.33Å; F200-F271 HydrophobicContact CB-CE1 3.81Å; F200-F271 AromaticContact CD1-CE1 3.71Å; F200-F271 HydrophobicContact CD1-CE1 3.71Å; F200-F271 AromaticContact CD1-CZ 3.64Å; F200-F271 HydrophobicContact CD1-CZ 3.64Å; F200-F271 HydrophobicContact CD2-CE1 4.14Å; F200-F271 HydrophobicContact CD2-CZ 4.28Å; F200-F271 HydrophobicContact CE1-CE1 4.23Å; F200-F271 AromaticContact CE1-CZ 3.69Å; F200-F271 HydrophobicContact CE1-CZ 3.69Å; F200-F271 HydrophobicContact CE2-CZ 4.35Å; F200-F271 AromaticContact CG-CE1 3.64Å; F200-F271 HydrophobicContact CG-CE1 3.64Å; F200-F271 AromaticContact CG-CZ 3.94Å; F200-F271 HydrophobicContact CG-CZ 3.94Å; F200-F271 HydrophobicContact CZ-CZ 4.07Å
201L98.8Very high98.5Very high22 Ų2233.4 Ų33.412%0.11515%0.15CC..Hα-helixtrans-62.1-35.3179.3-71.1174.6000112.8E197 E198 I199 W203 L204 R205 L270 F274E197-L201 WeakPolarHBondContact O-CG 3.36Å; E197-L201 PolarHBondContact O-N 3.41Å; E198-L201 PolarHBondContact O-N 3.46Å; I199-L201 VanDerWaalsContact C-N 3.34Å; I199-L201 PolarHBondContact O-N 2.95Å; L201-W203 PolarHBondContact O-N 3.04Å; L201-L204 PolarHBondContact O-N 3.27Å; L201-R205 VanDerWaalsContact CB-CZ 3.5Å; L201-R205 VanDerWaalsContact CB-NH2 3.3Å; L201-R205 WeakPolarHBondContact O-CB 3.45Å; L201-R205 VanDerWaalsContact O-CG 3.24Å; L201-R205 WeakPolarHBondContact O-CG 3.3Å; L201-R205 PolarHBondContact O-N 2.94Å; L201-R205 PolarHBondContact O-NE 2.96Å; L201-L270 HydrophobicContact CD1-CD1 4.1Å; L201-L270 HydrophobicContact CD2-CD1 3.92Å; L201-L270 HydrophobicContact CD2-CD2 4.44Å; L201-L270 HydrophobicContact CD2-CG 4.15Å; L201-L270 HydrophobicContact CG-CD1 4.1Å; L201-L270 HydrophobicContact CG-CD2 4.15Å; L201-L270 HydrophobicContact CG-CG 4.36Å; L201-F274 HydrophobicContact CD2-CB 4.46Å; L201-F274 HydrophobicContact CD2-CD2 3.71Å; L201-F274 HydrophobicContact CD2-CE2 4.42Å; L201-F274 HydrophobicContact CD2-CG 4.42Å
202H98.7Very high98.6Very high51 Ų5131.4 Ų31.424%0.23614%0.14CC..Hα-helixtrans-55.1-51.2176173.684.4000111.5R80 E198 I199 F200 R205 L206R80-H202 PolarHBondContact O-NE2 3.38Å; E198-H202 WeakPolarHBondContact O-CB 3.04Å; E198-H202 PolarHBondContact O-N 2.86Å; I199-H202 WeakPolarHBondContact O-CB 3.39Å; I199-H202 PolarHBondContact O-N 3.2Å; F200-H202 VanDerWaalsContact C-N 3.29Å; F200-H202 PolarHBondContact O-N 3.5Å; H202-R205 PolarHBondContact O-N 3.44Å; H202-L206 PolarHBondContact O-N 3.48Å
203W98.8Very high98.6Very high0 Ų031.4 Ų31.40%014%0.139CC..Hα-helixtrans-72.6-36.1-179.9-65.5111.9000113.2Y65 Y79 V82 L92 M108 I199 F200 L201 R205 L206 G207 V208 F211Y65-W203 AromaticContact CD1-CZ2 3.62Å; Y65-W203 HydrophobicContact CD1-CZ2 3.62Å; Y65-W203 HydrophobicContact CE1-CD2 4.37Å; Y65-W203 AromaticContact CE1-CE2 3.48Å; Y65-W203 VanDerWaalsContact CE1-CE2 3.48Å; Y65-W203 AromaticContact CE1-CZ2 3.57Å; Y65-W203 HydrophobicContact CE1-CZ2 3.57Å; Y65-W203 AromaticContact CE1-NE1 3.38Å; Y79-W203 VanDerWaalsContact O-CE2 3.23Å; Y79-W203 WeakPolarHBondContact O-CZ2 3.28Å; Y79-W203 PolarHBondContact O-NE1 3.41Å; V82-W203 HydrophobicContact CG2-CH2 4.1Å; V82-W203 HydrophobicContact CG2-CZ3 4.45Å; L92-W203 HydrophobicContact CD2-CE3 3.81Å; L92-W203 HydrophobicContact CD2-CH2 4.27Å; L92-W203 HydrophobicContact CD2-CZ3 3.42Å; L92-W203 VanDerWaalsContact CD2-CZ3 3.42Å; M108-W203 HydrophobicContact CE-CD2 4.24Å; M108-W203 HydrophobicContact CE-CE3 4.31Å; M108-W203 HydrophobicContact SD-CB 4.23Å; M108-W203 HydrophobicContact SD-CD2 3.82Å; M108-W203 HydrophobicContact SD-CE3 3.86Å; M108-W203 HydrophobicContact SD-CG 3.99Å; I199-W203 PolarHBondContact O-N 3.42Å; F200-W203 PolarHBondContact O-N 2.87Å; L201-W203 PolarHBondContact O-N 3.04Å; W203-R205 VanDerWaalsContact C-N 3.29Å; W203-R205 PolarHBondContact O-N 2.62Å; W203-L206 HydrophobicContact CE3-CD2 3.73Å; W203-L206 HydrophobicContact CZ3-CD2 3.61Å; W203-L206 WeakPolarHBondContact O-CB 3.42Å; W203-L206 PolarHBondContact O-N 2.53Å; W203-L206 VanDerWaalsContact O-N 3.1Å; W203-G207 PolarHBondContact O-N 3.25Å; W203-G207 VanDerWaalsContact O-N 3.14Å; W203-V208 HydrophobicContact CB-CB 4.33Å; W203-V208 HydrophobicContact CB-CG2 4Å; W203-V208 WeakPolarHBondContact O-CB 3.09Å; W203-V208 WeakPolarHBondContact O-CG2 3.39Å; W203-V208 PolarHBondContact O-N 3.49Å; W203-V208 VanDerWaalsContact O-N 3.15Å; W203-F211 HydrophobicContact CB-CE1 4.1Å; W203-F211 HydrophobicContact CB-CZ 4.14Å
204L98.8Very high98.6Very high2 Ų228.3 Ų28.31%0.0113%0.126CC..Hα-helixtrans-60.9-38.2173.4-72178.7000112.3F200 L201 L206 G207 V208 F211 F271 F274 I282F200-L204 WeakPolarHBondContact O-CG 3.15Å; F200-L204 PolarHBondContact O-N 3.28Å; L201-L204 PolarHBondContact O-N 3.27Å; L204-L206 VanDerWaalsContact C-N 3.32Å; L204-G207 PolarHBondContact O-N 3.14Å; L204-V208 WeakPolarHBondContact CD2-O 3.44Å; L204-F211 HydrophobicContact CD1-CE2 4.09Å; L204-F211 HydrophobicContact CD2-CE2 3.61Å; L204-F211 HydrophobicContact CD2-CZ 3.94Å; L204-F211 HydrophobicContact CG-CE2 3.66Å; L204-F211 HydrophobicContact CG-CZ 3.83Å; L204-F271 HydrophobicContact CD1-CD1 4.06Å; L204-F274 HydrophobicContact CB-CD1 3.94Å; L204-F274 HydrophobicContact CB-CD2 4.29Å; L204-F274 HydrophobicContact CB-CE1 3.66Å; L204-F274 HydrophobicContact CB-CE2 4.02Å; L204-F274 HydrophobicContact CB-CG 4.26Å; L204-F274 HydrophobicContact CB-CZ 3.7Å; L204-F274 HydrophobicContact CD1-CB 4.16Å; L204-F274 HydrophobicContact CD1-CD1 4Å; L204-F274 HydrophobicContact CD1-CD2 4.42Å; L204-F274 HydrophobicContact CD1-CG 3.92Å; L204-F274 HydrophobicContact CG-CD1 4.4Å; L204-F274 WeakPolarHBondContact O-CZ 3.44Å; L204-I282 HydrophobicContact CD2-CD1 3.84Å; L204-I282 HydrophobicContact CD2-CG1 4.29Å; L204-I282 HydrophobicContact CD2-CG2 3.84Å
205R98.4Very high98.6Very high140 Ų14022.4 Ų22.453%0.52811%0.105SC..Hα-helixtrans-66.5-31.5173.6-76.3179.9-79.6-115.57.1112.6E198 L201 H202 W203 G207 F274E198-R205 IonicContact OE2-CZ 2.88Å; E198-R205 IonicContact OE2-NH1 2.86Å; E198-R205 IonicContact OE2-NH2 2.63Å; E198-R205 PolarHBondContact OE2-NH2 3.04Å; L201-R205 VanDerWaalsContact CB-CZ 3.5Å; L201-R205 VanDerWaalsContact CB-NH2 3.3Å; L201-R205 WeakPolarHBondContact O-CB 3.45Å; L201-R205 VanDerWaalsContact O-CG 3.24Å; L201-R205 WeakPolarHBondContact O-CG 3.3Å; L201-R205 PolarHBondContact O-N 2.94Å; L201-R205 PolarHBondContact O-NE 2.96Å; H202-R205 PolarHBondContact O-N 3.44Å; W203-R205 VanDerWaalsContact C-N 3.29Å; W203-R205 PolarHBondContact O-N 2.62Å; R205-G207 VanDerWaalsContact C-N 3.28Å; R205-F274 HydrophobicContact CG-CE2 3.98Å; R205-F274 HydrophobicContact CG-CZ 4.33Å
206L98.1Very high98.6Very high38 Ų3820.3 Ų20.320%0.19910%0.095CC..Hα-helixtrans-72.4-23.5174.6-162.767.3000112.6L92 K93 H202 W203 L204L92-L206 HydrophobicContact CD2-CD2 4.14Å; K93-L206 HydrophobicContact CB-CD1 3.98Å; K93-L206 HydrophobicContact CB-CG 4.2Å; K93-L206 HydrophobicContact CD-CD1 4.25Å; K93-L206 HydrophobicContact CG-CD1 3.98Å; K93-L206 HydrophobicContact CG-CG 4.3Å; H202-L206 PolarHBondContact O-N 3.48Å; W203-L206 HydrophobicContact CE3-CD2 3.73Å; W203-L206 HydrophobicContact CZ3-CD2 3.61Å; W203-L206 WeakPolarHBondContact O-CB 3.42Å; W203-L206 PolarHBondContact O-N 2.53Å; W203-L206 VanDerWaalsContact O-N 3.1Å; L204-L206 VanDerWaalsContact C-N 3.32Å
207G98.1Very high98.5Very high13 Ų1320.3 Ų20.313%0.13410%0.095CC..THydrogen-bonded Turntrans1272.7173.200000115H100 W203 L204 R205H100-G207 PolarHBondContact CE1-O 3.29Å; H100-G207 PolarHBondContact NE2-O 2.88Å; W203-G207 PolarHBondContact O-N 3.25Å; W203-G207 VanDerWaalsContact O-N 3.14Å; L204-G207 PolarHBondContact O-N 3.14Å; R205-G207 VanDerWaalsContact C-N 3.28Å
208V98.7Very high98.5Very high0 Ų018.9 Ų18.90%09%0.088CC..  trans-56.2144177.5174.60000111.4I96 M108 W203 L204 G210 F211 K280I96-V208 HydrophobicContact CD1-CG2 3.85Å; M108-V208 HydrophobicContact CB-CG1 4.29Å; M108-V208 HydrophobicContact CG-CG1 3.96Å; M108-V208 HydrophobicContact CG-CG2 3.89Å; M108-V208 HydrophobicContact SD-CG1 4.47Å; M108-V208 HydrophobicContact SD-CG2 3.56Å; M108-V208 VanDerWaalsContact SD-CG2 3.56Å; W203-V208 HydrophobicContact CB-CB 4.33Å; W203-V208 HydrophobicContact CB-CG2 4Å; W203-V208 WeakPolarHBondContact O-CB 3.09Å; W203-V208 WeakPolarHBondContact O-CG2 3.39Å; W203-V208 PolarHBondContact O-N 3.49Å; W203-V208 VanDerWaalsContact O-N 3.15Å; L204-V208 WeakPolarHBondContact CD2-O 3.44Å; V208-G210 VanDerWaalsContact CG1-O 3.23Å; V208-G210 WeakPolarHBondContact CG1-O 3.18Å; V208-F211 HydrophobicContact CG1-CE1 4.02Å; V208-F211 HydrophobicContact CG1-CZ 4.21Å; V208-K280 PolarHBondContact O-NZ 2.89Å
209D98.7Very high98.5Very high7 Ų714.8 Ų14.84%0.0377%0.068CC..  trans-102.1-8.4-172.6-60-67.7000113.4W16 H100 F105 L106 I282 F283W16-D209 HydrophobicContact CZ2-CB 4.01Å; H100-D209 IonicContact CD2-OD2 3.61Å; H100-D209 IonicContact CE1-OD1 2.71Å; H100-D209 IonicContact CE1-OD2 3.55Å; H100-D209 IonicContact NE2-OD1 2.91Å; H100-D209 PolarHBondContact NE2-OD1 3.27Å; H100-D209 IonicContact NE2-OD2 3.36Å; H100-D209 PolarHBondContact NE2-OD2 3.03Å; F105-D209 VanDerWaalsContact CA-OD2 3.23Å; F105-D209 WeakPolarHBondContact CA-OD2 3.17Å; F105-D209 HydrophobicContact CB-CB 3.94Å; F105-D209 HydrophobicContact CD1-CB 4.19Å; L106-D209 PolarHBondContact N-OD2 3.35Å; L106-D209 WeakPolarHBondContact O-CB 3.42Å; L106-D209 PolarHBondContact O-N 3.21Å; D209-I282 WeakPolarHBondContact O-CA 3.5Å; D209-F283 PolarHBondContact O-N 3.13Å
210G98.7Very high98.4Very high0 Ų015.2 Ų15.20%07%0.071CC..EExtended strand (participates in β ladder)trans170.4-177.717500000114.1V107 M108 V208 F283V107-G210 WeakPolarHBondContact CA-O 3.36Å; M108-G210 PolarHBondContact N-O 2.94Å; V208-G210 VanDerWaalsContact CG1-O 3.23Å; V208-G210 WeakPolarHBondContact CG1-O 3.18Å; G210-F283 CarbonylContact C-O 3.5Å; G210-F283 WeakPolarHBondContact CA-O 3.4Å
211F98.8Very high98.4Very high0 Ų015.3 Ų15.30%07%0.071CC..EExtended strand (participates in β ladder)trans-132.6139.8-176.7-56.7-77.6000112.5M108 M110 F200 W203 L204 V208 I213 F271 F283 S284 M285M108-F211 HydrophobicContact CB-CD1 4.2Å; M108-F211 HydrophobicContact CB-CE1 4.38Å; M108-F211 CarbonylContact O-C 3.47Å; M108-F211 VanDerWaalsContact O-CA 3.26Å; M108-F211 WeakPolarHBondContact O-CA 3.49Å; M110-F211 HydrophobicContact CB-CD1 4.34Å; M110-F211 HydrophobicContact CE-CD1 4.17Å; M110-F211 HydrophobicContact CE-CE1 4.03Å; F200-F211 HydrophobicContact CB-CE2 4.27Å; F200-F211 HydrophobicContact CB-CZ 4.38Å; F200-F211 AromaticContact CD1-CD1 3.98Å; F200-F211 HydrophobicContact CD1-CD1 3.98Å; F200-F211 AromaticContact CD1-CD2 3.62Å; F200-F211 HydrophobicContact CD1-CD2 3.62Å; F200-F211 AromaticContact CD1-CE1 3.99Å; F200-F211 HydrophobicContact CD1-CE1 3.99Å; F200-F211 AromaticContact CD1-CE2 3.62Å; F200-F211 HydrophobicContact CD1-CE2 3.62Å; F200-F211 AromaticContact CD1-CG 3.8Å; F200-F211 HydrophobicContact CD1-CG 3.8Å; F200-F211 AromaticContact CD1-CZ 3.82Å; F200-F211 HydrophobicContact CD1-CZ 3.82Å; F200-F211 HydrophobicContact CE1-CB 4.19Å; F200-F211 HydrophobicContact CE1-CD1 4.17Å; F200-F211 HydrophobicContact CE1-CD2 4Å; F200-F211 HydrophobicContact CE1-CE2 4.45Å; F200-F211 AromaticContact CE1-CG 3.85Å; F200-F211 HydrophobicContact CE1-CG 3.85Å; F200-F211 HydrophobicContact CG-CE2 4.4Å; W203-F211 HydrophobicContact CB-CE1 4.1Å; W203-F211 HydrophobicContact CB-CZ 4.14Å; L204-F211 HydrophobicContact CD1-CE2 4.09Å; L204-F211 HydrophobicContact CD2-CE2 3.61Å; L204-F211 HydrophobicContact CD2-CZ 3.94Å; L204-F211 HydrophobicContact CG-CE2 3.66Å; L204-F211 HydrophobicContact CG-CZ 3.83Å; V208-F211 HydrophobicContact CG1-CE1 4.02Å; V208-F211 HydrophobicContact CG1-CZ 4.21Å; F211-I213 HydrophobicContact CB-CG1 4.43Å; F211-F271 HydrophobicContact CD2-CD1 4.42Å; F211-F271 AromaticContact CD2-CE1 3.81Å; F211-F271 HydrophobicContact CD2-CE1 3.81Å; F211-F271 HydrophobicContact CD2-CE2 4.02Å; F211-F271 AromaticContact CD2-CZ 3.57Å; F211-F271 HydrophobicContact CD2-CZ 3.57Å; F211-F271 HydrophobicContact CE2-CD1 4.36Å; F211-F271 AromaticContact CE2-CE1 3.87Å; F211-F271 HydrophobicContact CE2-CE1 3.87Å; F211-F271 HydrophobicContact CE2-CZ 4.13Å; F211-F271 HydrophobicContact CG-CZ 4.42Å; F211-F283 PolarHBondContact N-O 3.46Å; F211-S284 WeakPolarHBondContact O-CA 3.35Å; F211-M285 PolarHBondContact O-N 3.29Å
212R98.7Very high98.3Very high2 Ų216 Ų161%0.0088%0.075CC..EExtended strand (participates in β ladder)trans-89.6127152.9-177.4-98.4-175167.3-11.3107.2W60 M108 D109 M110 D214 M285 E287 L307W60-R212 HydrophobicContact CD2-CB 4.34Å; W60-R212 HydrophobicContact CH2-CG 3.92Å; W60-R212 HydrophobicContact CZ2-CB 4.01Å; W60-R212 VanDerWaalsContact CZ2-CD 3.4Å; W60-R212 HydrophobicContact CZ2-CG 3.48Å; W60-R212 VanDerWaalsContact CZ2-CG 3.48Å; M108-R212 PolarHBondContact O-N 3.27Å; D109-R212 WeakPolarHBondContact OD1-CD 3.48Å; D109-R212 IonicContact OD1-CZ 2.88Å; D109-R212 IonicContact OD1-NE 3.55Å; D109-R212 IonicContact OD1-NH1 3.99Å; D109-R212 PolarHBondContact OD1-NH1 3.18Å; D109-R212 IonicContact OD2-CZ 3.62Å; D109-R212 IonicContact OD2-NH1 3.65Å; D109-R212 PolarHBondContact OD2-NH1 2.71Å; M110-R212 PolarHBondContact N-O 3.49Å; R212-D214 IonicContact CZ-OD1 2.66Å; R212-D214 VanDerWaalsContact NH1-CB 3.31Å; R212-D214 IonicContact NH1-OD1 3.9Å; R212-D214 PolarHBondContact NH1-OD1 2.92Å; R212-D214 IonicContact NH2-OD1 2.83Å; R212-D214 PolarHBondContact NH2-OD1 3.16Å; R212-M285 CarbonylContact C-O 3.6Å; R212-M285 WeakPolarHBondContact CA-O 3.47Å; R212-M285 HydrophobicContact CB-CE 3.52Å; R212-M285 HydrophobicContact CB-CG 3.91Å; R212-M285 HydrophobicContact CG-CE 3.74Å; R212-M285 HydrophobicContact CG-CG 3.95Å; R212-E287 IonicContact CZ-OE2 3.38Å; R212-E287 VanDerWaalsContact NH2-CB 3.3Å; R212-E287 IonicContact NH2-OE2 3.74Å; R212-E287 PolarHBondContact NH2-OE2 3.08Å; R212-L307 HydrophobicContact CG-CD1 4.29Å
213I98.7Very high98.1Very high0 Ų019.4 Ų19.40%09%0.091CC..EExtended strand (participates in β ladder)trans-102.6104.4-176.8-53176.4000107.4P112 F211 V216 W267 F271 M285 T286 E287P112-I213 HydrophobicContact CG-CG2 3.64Å; F211-I213 HydrophobicContact CB-CG1 4.43Å; I213-V216 HydrophobicContact CG2-CB 4.08Å; I213-V216 HydrophobicContact CG2-CG2 4.02Å; I213-W267 HydrophobicContact CD1-CE3 4.01Å; I213-W267 HydrophobicContact CG2-CE3 4.25Å; I213-W267 HydrophobicContact CG2-CZ3 3.77Å; I213-F271 HydrophobicContact CD1-CE2 4.41Å; I213-M285 PolarHBondContact N-O 2.89Å; I213-T286 HydrophobicContact CB-CG2 4.21Å; I213-T286 HydrophobicContact CD1-CG2 4.2Å; I213-E287 PolarHBondContact O-N 2.89Å
214D98.5Very high97.9Very high12 Ų1225.9 Ų25.96%0.06413%0.125CC..THydrogen-bonded Turntrans-72.2147.8-176.8-17877.4000112.8Y74 M110 V111 P112 R212 V216Y74-D214 WeakPolarHBondContact CE1-OD1 3.21Å; M110-D214 VanDerWaalsContact O-CB 3.3Å; M110-D214 WeakPolarHBondContact O-CB 3.22Å; M110-D214 PolarHBondContact O-N 2.73Å; V111-D214 HydrophobicContact CB-CB 4.41Å; V111-D214 HydrophobicContact CG2-CB 4.02Å; P112-D214 WeakPolarHBondContact CD-O 3.24Å; R212-D214 IonicContact CZ-OD1 2.66Å; R212-D214 VanDerWaalsContact NH1-CB 3.31Å; R212-D214 IonicContact NH1-OD1 3.9Å; R212-D214 PolarHBondContact NH1-OD1 2.92Å; R212-D214 IonicContact NH2-OD1 2.83Å; R212-D214 PolarHBondContact NH2-OD1 3.16Å; D214-V216 PolarHBondContact O-N 3.26Å
215A97.5Very high97.8Very high2 Ų227 Ų272%0.01713%0.13CC..THydrogen-bonded Turntrans50.932.7168.600000113.5N113 F178 I217 Y218 E287N113-A215 HydrophobicContact CB-CB 4.13Å; F178-A215 HydrophobicContact CE2-CB 3.74Å; F178-A215 HydrophobicContact CZ-CB 3.9Å; A215-I217 PolarHBondContact O-N 3.04Å; A215-Y218 HydrophobicContact CB-CD2 4.09Å; A215-Y218 PolarHBondContact O-N 2.87Å; A215-Y218 VanDerWaalsContact O-N 3.09Å; A215-E287 PolarHBondContact N-OE2 2.86Å
216V98.1Very high97.8Very high0 Ų022.2 Ų22.20%012%0.12CC..G310 helixtrans-69.6-24.8-16667.60000112.2I213 D214 Y218 V219 T260 V264 W267 T286 E287 Y298I213-V216 HydrophobicContact CG2-CB 4.08Å; I213-V216 HydrophobicContact CG2-CG2 4.02Å; D214-V216 PolarHBondContact O-N 3.26Å; V216-Y218 PolarHBondContact O-N 2.95Å; V216-Y218 VanDerWaalsContact O-N 3.16Å; V216-V219 HydrophobicContact CG2-CG1 4.44Å; V216-V219 VanDerWaalsContact O-CG2 3.24Å; V216-V219 WeakPolarHBondContact O-CG2 3.23Å; V216-V219 PolarHBondContact O-N 2.89Å; V216-T260 HydrophobicContact CG2-CG2 4.22Å; V216-T260 VanDerWaalsContact O-CG2 3.25Å; V216-T260 WeakPolarHBondContact O-CG2 3.34Å; V216-V264 HydrophobicContact CG2-CG2 3.41Å; V216-V264 VanDerWaalsContact CG2-CG2 3.41Å; V216-W267 HydrophobicContact CG2-CZ3 4.24Å; V216-T286 HydrophobicContact CB-CG2 4.41Å; V216-T286 HydrophobicContact CG1-CG2 3.85Å; V216-T286 HydrophobicContact CG2-CG2 4.27Å; V216-E287 WeakPolarHBondContact CG1-O 3.47Å; V216-E287 PolarHBondContact N-O 2.81Å; V216-Y298 HydrophobicContact CG1-CE1 3.86Å; V216-Y298 HydrophobicContact CG1-CE2 4.23Å; V216-Y298 VanDerWaalsContact CG1-OH 3.24Å; V216-Y298 WeakPolarHBondContact CG1-OH 3.4Å; V216-Y298 HydrophobicContact CG2-CE1 4.06Å
217I97.7Very high97.8Very high1 Ų124.9 Ų24.91%0.00514%0.135CC..G310 helixtrans-64.9-18.5177.965.8176.1000112.2A215 V255 D256 T290 Y298A215-I217 PolarHBondContact O-N 3.04Å; I217-V255 HydrophobicContact CB-CG2 3.86Å; I217-V255 HydrophobicContact CD1-CG2 3.73Å; I217-V255 HydrophobicContact CG1-CG2 3.76Å; I217-V255 CarbonylContact O-C 3.59Å; I217-V255 WeakPolarHBondContact O-CA 3.33Å; I217-D256 WeakPolarHBondContact CB-OD1 3.31Å; I217-D256 VanDerWaalsContact CG2-OD1 3.26Å; I217-D256 WeakPolarHBondContact CG2-OD1 3.4Å; I217-D256 PolarHBondContact O-N 2.96Å; I217-T290 HydrophobicContact CG2-CG2 4.04Å; I217-Y298 HydrophobicContact CG2-CE2 4.29Å
218Y98.2Very high97.7Very high19 Ų1924.4 Ų24.48%0.07513%0.129CC..G310 helixtrans-102.23.2-177.9-54.4-69.8000113.4N113 I158 T177 F178 A215 V216 M220 K221 V255N113-Y218 PolarHBondContact OD1-O 3.23Å; I158-Y218 HydrophobicContact CD1-CE1 4.22Å; I158-Y218 WeakPolarHBondContact CD1-OH 3.37Å; T177-Y218 HydrophobicContact CG2-CD1 3.75Å; T177-Y218 HydrophobicContact CG2-CD2 4.06Å; T177-Y218 HydrophobicContact CG2-CE1 4.11Å; T177-Y218 HydrophobicContact CG2-CE2 4.39Å; T177-Y218 HydrophobicContact CG2-CG 3.72Å; F178-Y218 HydrophobicContact CE1-CE2 4.5Å; F178-Y218 HydrophobicContact CE2-CD2 4.29Å; F178-Y218 AromaticContact CZ-CD2 3.95Å; F178-Y218 HydrophobicContact CZ-CD2 3.95Å; F178-Y218 AromaticContact CZ-CE2 3.86Å; F178-Y218 HydrophobicContact CZ-CE2 3.86Å; A215-Y218 HydrophobicContact CB-CD2 4.09Å; A215-Y218 PolarHBondContact O-N 2.87Å; A215-Y218 VanDerWaalsContact O-N 3.09Å; V216-Y218 PolarHBondContact O-N 2.95Å; V216-Y218 VanDerWaalsContact O-N 3.16Å; Y218-M220 PolarHBondContact O-N 2.91Å; Y218-K221 WeakPolarHBondContact O-CE 3.33Å; Y218-K221 PolarHBondContact O-NZ 3.35Å; Y218-V255 HydrophobicContact CD1-CB 4Å; Y218-V255 HydrophobicContact CD1-CG2 3.87Å; Y218-V255 HydrophobicContact CE1-CB 3.97Å; Y218-V255 HydrophobicContact CE1-CG2 3.67Å
219V98.1Very high97.6Very high1 Ų127.1 Ų27.11%0.00615%0.147CC..SBendtrans-69.7-35.4-172.7-62.60000113.3P112 N113 Y187 V216 T260 L263 W267P112-V219 HydrophobicContact CB-CG1 4.33Å; P112-V219 HydrophobicContact CG-CG1 3.98Å; N113-V219 HydrophobicContact CB-CG1 4.2Å; Y187-V219 HydrophobicContact CD2-CB 4.14Å; Y187-V219 HydrophobicContact CE2-CB 4.2Å; Y187-V219 HydrophobicContact CE2-CG1 4.43Å; V216-V219 HydrophobicContact CG2-CG1 4.44Å; V216-V219 VanDerWaalsContact O-CG2 3.24Å; V216-V219 WeakPolarHBondContact O-CG2 3.23Å; V216-V219 PolarHBondContact O-N 2.89Å; V219-T260 HydrophobicContact CG2-CG2 3.7Å; V219-L263 HydrophobicContact CB-CD2 4.24Å; V219-L263 HydrophobicContact CG2-CD2 3.84Å; V219-W267 HydrophobicContact CG1-CH2 4.36Å
220M98Very high97.4Very high10 Ų1031.6 Ų31.65%0.04917%0.174CC..  trans-106.4143.2176-63-59.8-68.700111.1Y187 R188 Y218 Q257 E259 T260 L263Y187-M220 VanDerWaalsContact CB-SD 3.57Å; R188-M220 HydrophobicContact CG-CE 4.23Å; Y218-M220 PolarHBondContact O-N 2.91Å; M220-Q257 HydrophobicContact CB-CB 3.96Å; M220-Q257 WeakPolarHBondContact O-CG 3.04Å; M220-E259 HydrophobicContact CB-CB 4.42Å; M220-E259 HydrophobicContact CE-CB 3.71Å; M220-E259 HydrophobicContact CE-CG 4.36Å; M220-E259 HydrophobicContact CG-CB 3.95Å; M220-T260 WeakPolarHBondContact CB-OG1 3.4Å; M220-L263 HydrophobicContact SD-CD2 4.29Å
221K97.4Very high96.9Very high1 Ų132.3 Ų32.30%0.00418%0.179CC..  trans-121.7151.1174.6-67.195.1-151.8-166.30110.6N113 I137 W155 L175 D184 R188 Y218N113-K221 PolarHBondContact OD1-NZ 3.17Å; I137-K221 HydrophobicContact CD1-CD 3.38Å; I137-K221 HydrophobicContact CD1-CG 4.47Å; W155-K221 HydrophobicContact CH2-CB 3.96Å; W155-K221 HydrophobicContact CH2-CG 4.27Å; W155-K221 HydrophobicContact CZ3-CB 4.19Å; W155-K221 HydrophobicContact CZ3-CG 4.04Å; L175-K221 HydrophobicContact CD2-CD 3.73Å; L175-K221 HydrophobicContact CD2-CG 3.99Å; D184-K221 WeakPolarHBondContact OD2-CE 3.31Å; D184-K221 IonicContact OD2-NZ 3.84Å; D184-K221 PolarHBondContact OD2-NZ 2.71Å; R188-K221 PolarHBondContact NH1-O 2.51Å; R188-K221 PolarHBondContact NH2-O 3.24Å; Y218-K221 WeakPolarHBondContact O-CE 3.33Å; Y218-K221 PolarHBondContact O-NZ 3.35Å
222N97.1Very high96.1Very high36 Ų3637.5 Ų37.519%0.19321%0.206CC..  trans-60.1139.4177.8-167.1-83.7000111.5D224 F225 Y253 Q257N222-D224 VanDerWaalsContact C-N 3.28Å; N222-D224 PolarHBondContact O-N 3.14Å; N222-D224 WeakPolarHBondContact OD1-CB 3.23Å; N222-D224 PolarHBondContact OD1-N 3.45Å; N222-F225 WeakPolarHBondContact O-CD2 3.21Å; N222-F225 PolarHBondContact O-N 2.91Å; N222-Y253 HydrophobicContact CB-CD1 4.2Å; N222-Y253 HydrophobicContact CB-CG 4.47Å; N222-Y253 WeakPolarHBondContact CB-O 3.43Å; N222-Y253 PolarHBondContact N-O 2.95Å; N222-Q257 VanDerWaalsContact CB-OE1 3.31Å; N222-Q257 PolarHBondContact ND2-OE1 2.89Å; N222-Q257 VanDerWaalsContact ND2-OE1 3.12Å
223E94.5Very high95.1Very high124 Ų12445 Ų4558%0.57925%0.246SC*.THydrogen-bonded Turntrans-67.7-26.3-176.1-68.6-163.6168.300114.3R188 F225R188-E223 IonicContact CZ-OE1 3.47Å; R188-E223 VanDerWaalsContact NE-CG 3.28Å; R188-E223 IonicContact NE-OE1 3.9Å; R188-E223 PolarHBondContact NE-OE1 3.5Å; R188-E223 IonicContact NH2-OE1 3.52Å; E223-F225 VanDerWaalsContact C-N 3.27Å; E223-F225 VanDerWaalsContact O-CD2 3.27Å; E223-F225 WeakPolarHBondContact O-CD2 3.5Å; E223-F225 PolarHBondContact O-N 2.89Å
224D95.9Very high93.9Very high135 Ų13549.2 Ų49.272%0.72229%0.289SS*.THydrogen-bonded Turntrans-79.3-16.3-177.7-62.6-25.6000111.7N222 A226N222-D224 VanDerWaalsContact C-N 3.28Å; N222-D224 PolarHBondContact O-N 3.14Å; N222-D224 WeakPolarHBondContact OD1-CB 3.23Å; N222-D224 PolarHBondContact OD1-N 3.45Å; D224-A226 PolarHBondContact O-N 3.33Å; D224-A226 VanDerWaalsContact O-N 3.1Å
225F96.7Very high93Very high27 Ų2754.2 Ų54.212%0.11831%0.312CS..  trans49.333.8-175.1-72-96.5000112.9I137 K139 N153 W155 W164 N222 E223I137-F225 HydrophobicContact CG2-CE1 3.62Å; I137-F225 HydrophobicContact CG2-CZ 3.78Å; K139-F225 VanDerWaalsContact NZ-CE2 3.32Å; N153-F225 WeakPolarHBondContact CB-O 3.37Å; N153-F225 PolarHBondContact ND2-O 3.24Å; W155-F225 HydrophobicContact CH2-CB 4.44Å; W155-F225 AromaticContact CH2-CD1 3.41Å; W155-F225 HydrophobicContact CH2-CD1 3.41Å; W155-F225 VanDerWaalsContact CH2-CD1 3.41Å; W155-F225 AromaticContact CH2-CE1 3.87Å; W155-F225 HydrophobicContact CH2-CE1 3.87Å; W155-F225 HydrophobicContact CH2-CG 4.12Å; W155-F225 HydrophobicContact CZ2-CD1 4.28Å; W155-F225 AromaticContact CZ3-CD1 3.66Å; W155-F225 HydrophobicContact CZ3-CD1 3.66Å; W155-F225 AromaticContact CZ3-CE1 3.88Å; W155-F225 HydrophobicContact CZ3-CE1 3.88Å; W164-F225 HydrophobicContact CH2-CD1 4.04Å; W164-F225 HydrophobicContact CH2-CE1 4.05Å; W164-F225 HydrophobicContact CZ2-CD1 4.05Å; W164-F225 HydrophobicContact CZ2-CE1 4.41Å; N222-F225 WeakPolarHBondContact O-CD2 3.21Å; N222-F225 PolarHBondContact O-N 2.91Å; E223-F225 VanDerWaalsContact C-N 3.27Å; E223-F225 VanDerWaalsContact O-CD2 3.27Å; E223-F225 WeakPolarHBondContact O-CD2 3.5Å; E223-F225 PolarHBondContact O-N 2.89Å
226A97.3Very high92.1Very high38 Ų3858.5 Ų58.531%0.31434%0.338SS..PPolyproline II helixtrans-64.1154.3179.800000112.1W155 D224 Y253W155-A226 PolarHBondContact NE1-O 2.96Å; D224-A226 PolarHBondContact O-N 3.33Å; D224-A226 VanDerWaalsContact O-N 3.1Å; A226-Y253 HydrophobicContact CB-CD2 4.24Å; A226-Y253 HydrophobicContact CB-CE2 4.29Å
227D97.8Very high91.4Very high94 Ų9459.4 Ų59.450%0.50334%0.344SS..PPolyproline II helixtrans-57.1138.2171.1-73.8-38.1000111.3N153 N154 Y253N153-D227 VanDerWaalsContact CA-OD1 3.23Å; N153-D227 WeakPolarHBondContact CA-OD1 3.4Å; N153-D227 VanDerWaalsContact CB-OD1 3.29Å; N153-D227 WeakPolarHBondContact CB-OD1 3.49Å; N154-D227 PolarHBondContact N-OD1 3.31Å; N154-D227 VanDerWaalsContact OD1-CA 3.26Å; N154-D227 WeakPolarHBondContact OD1-CA 3.24Å; N154-D227 WeakPolarHBondContact OD1-CB 3.15Å; N154-D227 PolarHBondContact OD1-OD1 2.98Å; D227-Y253 VanDerWaalsContact O-CD2 3.31Å; D227-Y253 WeakPolarHBondContact O-CD2 3.48Å; D227-Y253 WeakPolarHBondContact O-CE2 3.35Å
228N97.3Very high90.7Very high4 Ų464.9 Ų64.92%0.02139%0.39CS..PPolyproline II helixtrans-69.2151167.4-80-28.8000110.7N154 W155 V230 T249 V250 K252 Y253 N254N154-N228 PolarHBondContact ND2-O 3.12Å; N154-N228 PolarHBondContact OD1-N 3.01Å; W155-N228 VanDerWaalsContact CD1-ND2 3.34Å; N228-V230 PolarHBondContact O-N 3.12Å; N228-T249 HydrophobicContact CB-CG2 4.41Å; N228-V250 WeakPolarHBondContact CB-O 3.48Å; N228-K252 PolarHBondContact OD1-N 3.39Å; N228-Y253 WeakPolarHBondContact OD1-CD2 3.35Å; N228-Y253 PolarHBondContact OD1-N 3.14Å; N228-N254 PolarHBondContact ND2-OD1 3.28Å
229P95.5Very high90.1Very high57 Ų5768 Ų6837%0.3741%0.408SS..PPolyproline II helixtrans-54.8128.7173-24.633.8000112T249 V250 K252P229-T249 CarbonylContact O-C 3.5Å; P229-T249 WeakPolarHBondContact O-CA 3.48Å; P229-T249 WeakPolarHBondContact O-CB 3.4Å; P229-V250 WeakPolarHBondContact CD-O 3.26Å; P229-V250 PolarHBondContact O-N 2.86Å; P229-K252 HydrophobicContact CG-CD 4.16Å
230V94.3Very high89.4Confident100 Ų10073.4 Ų73.461%0.60643%0.431SS*.BIsolated β-bridgetrans-79142.3179.3-1800000110.5N228N228-V230 PolarHBondContact O-N 3.12Å
231V89.5Confident88.8Confident16 Ų1674.9 Ų74.910%0.09744%0.441CS..PPolyproline II helixtrans-95.4122.3170.2-176.60000108.4E235 P237 L248 V250V231-E235 WeakPolarHBondContact CG1-O 3.43Å; V231-P237 HydrophobicContact CG1-CG 4.46Å; V231-P237 HydrophobicContact CG2-CB 4.07Å; V231-P237 HydrophobicContact CG2-CG 3.99Å; V231-L248 PolarHBondContact N-O 2.61Å; V231-V250 HydrophobicContact CG2-CG2 3.76Å
232L82Confident88.5Confident108 Ų10876 Ų7657%0.56545%0.446SS*.PPolyproline II helixtrans-72.4146.7178.4-62.6177.5000111G234 E235L232-G234 PolarHBondContact O-N 3.09Å; L232-E235 HydrophobicContact CB-CB 4.41Å; L232-E235 HydrophobicContact CB-CG 4.14Å; L232-E235 WeakPolarHBondContact O-CB 3.13Å; L232-E235 PolarHBondContact O-N 3.48Å
233D77.7Confident88.1Confident159 Ų15976.9 Ų76.985%0.8545%0.447SS*.THydrogen-bonded Turntrans-52.9124.3-176.7-73.9-25.1000112.5E235D233-E235 PolarHBondContact O-N 3.3Å
234G72.6Confident87.7Confident89 Ų8975.4 Ų75.492%0.91844%0.44SS*.THydrogen-bonded Turntrans78.1-3.2179.300000115L232L232-G234 PolarHBondContact O-N 3.09Å
235E79.8Confident87Confident117 Ų11774.7 Ų74.755%0.54745%0.445SS..  trans-88.7153.1174.2-62.4-165.9168.100111.9V231 L232 D233V231-E235 WeakPolarHBondContact CG1-O 3.43Å; L232-E235 HydrophobicContact CB-CB 4.41Å; L232-E235 HydrophobicContact CB-CG 4.14Å; L232-E235 WeakPolarHBondContact O-CB 3.13Å; L232-E235 PolarHBondContact O-N 3.48Å; D233-E235 PolarHBondContact O-N 3.3Å
236V78.6Confident86.3Confident92 Ų9276.5 Ų76.556%0.55847%0.472SS*.  trans-105.5122.6171.2173.70000105.8K240V236-K240 HydrophobicContact CG1-CD 4.35Å
237P84.3Confident85.9Confident19 Ų1975.7 Ų75.712%0.12346%0.462CS..  trans-64.2150.1-175.826.4-33.3000111.4V231 D239 K240 W243 V250V231-P237 HydrophobicContact CG1-CG 4.46Å; V231-P237 HydrophobicContact CG2-CB 4.07Å; V231-P237 HydrophobicContact CG2-CG 3.99Å; P237-D239 VanDerWaalsContact C-N 3.34Å; P237-D239 WeakPolarHBondContact CB-O 3.5Å; P237-K240 HydrophobicContact CG-CG 4.34Å; P237-W243 HydrophobicContact CG-CB 4.22Å; P237-W243 HydrophobicContact CG-CD2 3.75Å; P237-W243 HydrophobicContact CG-CE3 4.24Å; P237-W243 HydrophobicContact CG-CG 3.72Å; P237-V250 HydrophobicContact CB-CG2 3.6Å; P237-V250 HydrophobicContact CG-CG2 3.85Å
238A82.3Confident85.6Confident117 Ų11776.1 Ų76.197%0.96746%0.464SS*.SBendtrans-65.4-40.1178.200000111.7
239D85.3Confident85.4Confident84 Ų8476.2 Ų76.245%0.44946%0.464SS..  trans-99.6123.6171.1-177.71.8000109.4P237 T241P237-D239 VanDerWaalsContact C-N 3.34Å; P237-D239 WeakPolarHBondContact CB-O 3.5Å; D239-T241 WeakPolarHBondContact OD1-CB 3.26Å; D239-T241 PolarHBondContact OD1-N 2.74Å; D239-T241 PolarHBondContact OD1-OG1 3.22Å
240K84Confident85.4Confident114 Ų11474 Ų7450%0.49645%0.449SS..  trans-117.38.2-178.4-64.8178.7176.6-178.80113.2V236 P237 H242 W243V236-K240 HydrophobicContact CG1-CD 4.35Å; P237-K240 HydrophobicContact CG-CG 4.34Å; K240-H242 PolarHBondContact O-N 3.24Å; K240-W243 PolarHBondContact O-N 2.97Å
241T85.8Confident85.4Confident42 Ų4269.4 Ų69.426%0.25842%0.422SS..SBendtrans-49.2-41.7-166.5-58.40000112.6D239 D291D239-T241 WeakPolarHBondContact OD1-CB 3.26Å; D239-T241 PolarHBondContact OD1-N 2.74Å; D239-T241 PolarHBondContact OD1-OG1 3.22Å; T241-D291 HydrophobicContact CG2-CB 3.77Å
242H90Very high85.7Confident24 Ų2473.8 Ų73.811%0.11144%0.44CS..SBendtrans-118.81.4176.9-52114000114.2K240 P251 V255 D256 T290K240-H242 PolarHBondContact O-N 3.24Å; H242-P251 HydrophobicContact CB-CB 3.72Å; H242-P251 HydrophobicContact CB-CG 3.94Å; H242-P251 PolarHBondContact ND1-O 3.45Å; H242-V255 HydrophobicContact CB-CG1 4.4Å; H242-V255 WeakPolarHBondContact ND1-CG1 3.32Å; H242-D256 IonicContact CE1-OD2 3.94Å; H242-D256 IonicContact NE2-OD2 2.65Å; H242-D256 PolarHBondContact NE2-OD2 2.97Å; H242-T290 PolarHBondContact NE2-OG1 3.28Å
243W89.8Confident86.4Confident54 Ų5471.7 Ų71.721%0.20543%0.425CS..  trans-80.3128.5-173.2-179.982.7000110.8P237 K240 M247 V250P237-W243 HydrophobicContact CG-CB 4.22Å; P237-W243 HydrophobicContact CG-CD2 3.75Å; P237-W243 HydrophobicContact CG-CE3 4.24Å; P237-W243 HydrophobicContact CG-CG 3.72Å; K240-W243 PolarHBondContact O-N 2.97Å; W243-M247 PolarHBondContact NE1-O 3.03Å; W243-V250 HydrophobicContact CB-CG1 4.49Å; W243-V250 HydrophobicContact CB-CG2 4.38Å
244Q85.1Confident87.3Confident94 Ų9464.4 Ų64.444%0.43939%0.386SS..  trans-108.5150.1173.5-57.5-177.733.800110.2G246 M247Q244-G246 PolarHBondContact O-N 2.9Å; Q244-G246 VanDerWaalsContact O-N 3.14Å; Q244-M247 HydrophobicContact CB-CG 4.19Å; Q244-M247 HydrophobicContact CB-SD 3.94Å; Q244-M247 HydrophobicContact CG-SD 4.26Å; Q244-M247 WeakPolarHBondContact O-CB 3.31Å; Q244-M247 WeakPolarHBondContact O-CG 3.32Å; Q244-M247 PolarHBondContact O-N 2.9Å
245S81.7Confident88.5Confident119 Ų11960.2 Ų60.283%0.83234%0.342SS*.THydrogen-bonded Turntrans-56.7121.4178.5-177.60000110.6
246G82.3Confident89.3Confident66 Ų6655.4 Ų55.468%0.6832%0.32SS*.THydrogen-bonded Turntrans104.6-11.2-179.300000114.8Q244Q244-G246 PolarHBondContact O-N 2.9Å; Q244-G246 VanDerWaalsContact O-N 3.14Å
247M88.1Confident90.1Very high20 Ų2052 Ų5210%0.09930%0.298CS..  trans-73.6138.2172.5-61.7-174.97600111.2E156 W243 Q244 T249 P251E156-M247 HydrophobicContact CB-CE 4.14Å; W243-M247 PolarHBondContact NE1-O 3.03Å; Q244-M247 HydrophobicContact CB-CG 4.19Å; Q244-M247 HydrophobicContact CB-SD 3.94Å; Q244-M247 HydrophobicContact CG-SD 4.26Å; Q244-M247 WeakPolarHBondContact O-CB 3.31Å; Q244-M247 WeakPolarHBondContact O-CG 3.32Å; Q244-M247 PolarHBondContact O-N 2.9Å; M247-T249 VanDerWaalsContact C-N 3.34Å; M247-P251 HydrophobicContact CE-CG 3.48Å; M247-P251 VanDerWaalsContact CE-CG 3.48Å; M247-P251 HydrophobicContact SD-CG 4.18Å
248L91.4Very high90.7Very high104 Ų10454.4 Ų54.455%0.54532%0.32SS..SBendtrans-86-9.5178-58.3177.9000112.7E156 V231E156-L248 PolarHBondContact OE1-N 2.69Å; E156-L248 PolarHBondContact OE2-N 3.33Å; V231-L248 PolarHBondContact N-O 2.61Å
249T93.7Very high91.4Very high5 Ų552.3 Ų52.33%0.03129%0.29CS..BIsolated β-bridgetrans-135.2155.7-180670000111.2N154 E156 N228 P229 M247 P251N154-T249 HydrophobicContact CB-CG2 4.42Å; N154-T249 WeakPolarHBondContact ND2-CG2 3.33Å; E156-T249 WeakPolarHBondContact OE1-CB 3.21Å; E156-T249 PolarHBondContact OE1-N 3.13Å; E156-T249 PolarHBondContact OE1-OG1 3.42Å; N228-T249 HydrophobicContact CB-CG2 4.41Å; P229-T249 CarbonylContact O-C 3.5Å; P229-T249 WeakPolarHBondContact O-CA 3.48Å; P229-T249 WeakPolarHBondContact O-CB 3.4Å; M247-T249 VanDerWaalsContact C-N 3.34Å; T249-P251 WeakPolarHBondContact O-CD 3.21Å
250V94.6Very high92Very high10 Ų1048.3 Ų48.36%0.06127%0.269CS..  trans-93.2113.5169.7-178.30000108.5N228 P229 V231 P237 W243 K252N228-V250 WeakPolarHBondContact CB-O 3.48Å; P229-V250 WeakPolarHBondContact CD-O 3.26Å; P229-V250 PolarHBondContact O-N 2.86Å; V231-V250 HydrophobicContact CG2-CG2 3.76Å; P237-V250 HydrophobicContact CB-CG2 3.6Å; P237-V250 HydrophobicContact CG-CG2 3.85Å; W243-V250 HydrophobicContact CB-CG1 4.49Å; W243-V250 HydrophobicContact CB-CG2 4.38Å; V250-K252 PolarHBondContact O-N 3.33Å
251P95.3Very high92.7Very high5 Ų544.1 Ų44.13%0.03225%0.25CS..  trans-58.6124.3177.7-24.334.1000111.9H242 M247 T249 V255H242-P251 HydrophobicContact CB-CB 3.72Å; H242-P251 HydrophobicContact CB-CG 3.94Å; H242-P251 PolarHBondContact ND1-O 3.45Å; M247-P251 HydrophobicContact CE-CG 3.48Å; M247-P251 VanDerWaalsContact CE-CG 3.48Å; M247-P251 HydrophobicContact SD-CG 4.18Å; T249-P251 WeakPolarHBondContact O-CD 3.21Å; P251-V255 HydrophobicContact CB-CG1 3.83Å
252K95.1Very high93.3Very high107 Ų10748 Ų4847%0.46527%0.265SS..  trans-141.8-43.4-176-177.4174.9-178.3176.20113.2N228 P229 V250 Q257N228-K252 PolarHBondContact OD1-N 3.39Å; P229-K252 HydrophobicContact CG-CD 4.16Å; V250-K252 PolarHBondContact O-N 3.33Å; K252-Q257 PolarHBondContact O-NE2 3.07Å
253Y97.1Very high93.7Very high65 Ų6547.1 Ų47.126%0.25526%0.261SS..SBendtrans-96.7-14.1-175.1-60.7-63.7000113N222 A226 D227 N228N222-Y253 HydrophobicContact CB-CD1 4.2Å; N222-Y253 HydrophobicContact CB-CG 4.47Å; N222-Y253 WeakPolarHBondContact CB-O 3.43Å; N222-Y253 PolarHBondContact N-O 2.95Å; A226-Y253 HydrophobicContact CB-CD2 4.24Å; A226-Y253 HydrophobicContact CB-CE2 4.29Å; D227-Y253 VanDerWaalsContact O-CD2 3.31Å; D227-Y253 WeakPolarHBondContact O-CD2 3.48Å; D227-Y253 WeakPolarHBondContact O-CE2 3.35Å; N228-Y253 WeakPolarHBondContact OD1-CD2 3.35Å; N228-Y253 PolarHBondContact OD1-N 3.14Å
254N96.6Very high94.1Very high5 Ų544.6 Ų44.63%0.02725%0.252CS..SBendtrans-106.69.3-179.262.1-48.2000113.8W155 N228W155-N254 HydrophobicContact CD2-CB 3.68Å; W155-N254 HydrophobicContact CE3-CB 3.68Å; W155-N254 HydrophobicContact CG-CB 4.29Å; W155-N254 HydrophobicContact CH2-CB 4.13Å; W155-N254 HydrophobicContact CZ2-CB 4.14Å; W155-N254 HydrophobicContact CZ3-CB 3.91Å; N228-N254 PolarHBondContact ND2-OD1 3.28Å
255V97.1Very high94.7Very high2 Ų244.1 Ų44.11%0.01225%0.248CC..SBendtrans-147.8152.8-176.563.60000110.1I217 Y218 H242 P251 Q257I217-V255 HydrophobicContact CB-CG2 3.86Å; I217-V255 HydrophobicContact CD1-CG2 3.73Å; I217-V255 HydrophobicContact CG1-CG2 3.76Å; I217-V255 CarbonylContact O-C 3.59Å; I217-V255 WeakPolarHBondContact O-CA 3.33Å; Y218-V255 HydrophobicContact CD1-CB 4Å; Y218-V255 HydrophobicContact CD1-CG2 3.87Å; Y218-V255 HydrophobicContact CE1-CB 3.97Å; Y218-V255 HydrophobicContact CE1-CG2 3.67Å; H242-V255 HydrophobicContact CB-CG1 4.4Å; H242-V255 WeakPolarHBondContact ND1-CG1 3.32Å; P251-V255 HydrophobicContact CB-CG1 3.83Å; V255-Q257 PolarHBondContact O-N 3.48Å; V255-Q257 VanDerWaalsContact O-N 3.09Å; V255-Q257 PolarHBondContact O-NE2 2.93Å
256D96.2Very high95.5Very high15 Ų1540.3 Ų40.38%0.0822%0.222CC..  trans50.537.5172.1-78.5-26.8000115.1I217 H242 T290 H294I217-D256 WeakPolarHBondContact CB-OD1 3.31Å; I217-D256 VanDerWaalsContact CG2-OD1 3.26Å; I217-D256 WeakPolarHBondContact CG2-OD1 3.4Å; I217-D256 PolarHBondContact O-N 2.96Å; H242-D256 IonicContact CE1-OD2 3.94Å; H242-D256 IonicContact NE2-OD2 2.65Å; H242-D256 PolarHBondContact NE2-OD2 2.97Å; D256-T290 WeakPolarHBondContact OD2-CB 3.49Å; D256-T290 PolarHBondContact OD2-OG1 2.95Å; D256-H294 IonicContact OD2-CD2 3.47Å; D256-H294 IonicContact OD2-CG 3.9Å
257Q97.3Very high96.3Very high21 Ų2137.2 Ų37.210%0.09819%0.189CC..  trans-70140.6172.2-56.6-56.8-75.400110.5M220 N222 K252 V255 E259 T260M220-Q257 HydrophobicContact CB-CB 3.96Å; M220-Q257 WeakPolarHBondContact O-CG 3.04Å; N222-Q257 VanDerWaalsContact CB-OE1 3.31Å; N222-Q257 PolarHBondContact ND2-OE1 2.89Å; N222-Q257 VanDerWaalsContact ND2-OE1 3.12Å; K252-Q257 PolarHBondContact O-NE2 3.07Å; V255-Q257 PolarHBondContact O-N 3.48Å; V255-Q257 VanDerWaalsContact O-N 3.09Å; V255-Q257 PolarHBondContact O-NE2 2.93Å; Q257-E259 PolarHBondContact O-N 3.05Å; Q257-E259 VanDerWaalsContact O-N 3.1Å; Q257-T260 WeakPolarHBondContact O-CB 3.33Å; Q257-T260 PolarHBondContact O-N 3.34Å; Q257-T260 PolarHBondContact O-OG1 3.12Å
258A96.6Very high96.8Very high70 Ų7036.5 Ų36.558%0.57919%0.186SC*.THydrogen-bonded Turntrans-57.1-31.9-17400000113.3T260 Y261A258-T260 PolarHBondContact O-N 3.4Å; A258-Y261 WeakPolarHBondContact O-CD2 3.48Å; A258-Y261 PolarHBondContact O-N 3.14Å
259E97Very high97.1Very high73 Ų7333.5 Ų33.534%0.34118%0.176SC..Hα-helixtrans-63.4-20.8177.1-5799.3117.600113.3R188 M220 Q257 Y261 E262 L263R188-E259 IonicContact NH2-OE1 2.75Å; R188-E259 PolarHBondContact NH2-OE1 3.18Å; M220-E259 HydrophobicContact CB-CB 4.42Å; M220-E259 HydrophobicContact CE-CB 3.71Å; M220-E259 HydrophobicContact CE-CG 4.36Å; M220-E259 HydrophobicContact CG-CB 3.95Å; Q257-E259 PolarHBondContact O-N 3.05Å; Q257-E259 VanDerWaalsContact O-N 3.1Å; E259-Y261 VanDerWaalsContact C-N 3.27Å; E259-Y261 PolarHBondContact O-N 3.38Å; E259-E262 PolarHBondContact O-N 3.44Å; E259-L263 PolarHBondContact O-N 3.09Å
260T98.1Very high97.3Very high0 Ų034.9 Ų34.90%018%0.184CC..Hα-helixtrans-57.2-42.8173.6-680000110.9V216 V219 M220 Q257 A258 E262 L263 V264 Y298V216-T260 HydrophobicContact CG2-CG2 4.22Å; V216-T260 VanDerWaalsContact O-CG2 3.25Å; V216-T260 WeakPolarHBondContact O-CG2 3.34Å; V219-T260 HydrophobicContact CG2-CG2 3.7Å; M220-T260 WeakPolarHBondContact CB-OG1 3.4Å; Q257-T260 WeakPolarHBondContact O-CB 3.33Å; Q257-T260 PolarHBondContact O-N 3.34Å; Q257-T260 PolarHBondContact O-OG1 3.12Å; A258-T260 PolarHBondContact O-N 3.4Å; T260-E262 PolarHBondContact O-N 2.99Å; T260-L263 PolarHBondContact O-N 3.18Å; T260-V264 HydrophobicContact CG2-CG2 4.5Å; T260-V264 WeakPolarHBondContact O-CG2 3.2Å; T260-V264 PolarHBondContact O-N 3.36Å; T260-Y298 HydrophobicContact CG2-CE1 4.03Å; T260-Y298 WeakPolarHBondContact CG2-OH 3.1Å
261Y97.9Very high97.5Very high26 Ų2634.6 Ų34.610%0.10218%0.181CC..Hα-helixtrans-66.4-38.8-178.4-57-68.6000112.1A258 E259 K265 H294 D297 Y298 S301A258-Y261 WeakPolarHBondContact O-CD2 3.48Å; A258-Y261 PolarHBondContact O-N 3.14Å; E259-Y261 VanDerWaalsContact C-N 3.27Å; E259-Y261 PolarHBondContact O-N 3.38Å; Y261-K265 WeakPolarHBondContact O-CB 3.34Å; Y261-K265 PolarHBondContact O-N 2.99Å; Y261-H294 WeakPolarHBondContact OH-CA 3.17Å; Y261-H294 PolarHBondContact OH-CD2 2.76Å; Y261-H294 PolarHBondContact OH-O 3.4Å; Y261-D297 HydrophobicContact CD1-CB 4.19Å; Y261-D297 HydrophobicContact CE1-CB 3.61Å; Y261-D297 HydrophobicContact CE2-CB 4.36Å; Y261-Y298 AromaticContact CD1-CD1 3.9Å; Y261-Y298 HydrophobicContact CD1-CD1 3.9Å; Y261-Y298 AromaticContact CD1-CE1 3.99Å; Y261-Y298 HydrophobicContact CD1-CE1 3.99Å; Y261-Y298 HydrophobicContact CD1-CG 4.21Å; Y261-Y298 HydrophobicContact CE1-CD1 4.09Å; Y261-Y298 AromaticContact CE1-CD2 3.96Å; Y261-Y298 HydrophobicContact CE1-CD2 3.96Å; Y261-Y298 HydrophobicContact CE1-CE1 4.05Å; Y261-Y298 AromaticContact CE1-CE2 3.95Å; Y261-Y298 HydrophobicContact CE1-CE2 3.95Å; Y261-Y298 HydrophobicContact CE1-CG 4.04Å; Y261-Y298 AromaticContact CE1-CZ 3.99Å; Y261-S301 VanDerWaalsContact CA-OG 3.32Å; Y261-S301 WeakPolarHBondContact CA-OG 3.45Å; Y261-S301 WeakPolarHBondContact CB-OG 3.22Å; Y261-S301 WeakPolarHBondContact O-CB 3.36Å; Y261-S301 PolarHBondContact O-OG 3.37Å
262E97.5Very high97.6Very high124 Ų12439.3 Ų39.358%0.57920%0.198SC*.Hα-helixtrans-69.9-35.4176-66.4-57.3144.300112E259 T260 K265 S266E259-E262 PolarHBondContact O-N 3.44Å; T260-E262 PolarHBondContact O-N 2.99Å; E262-K265 WeakPolarHBondContact O-CB 3.45Å; E262-K265 PolarHBondContact O-N 2.78Å; E262-S266 PolarHBondContact O-N 2.71Å; E262-S266 VanDerWaalsContact O-N 3.15Å
263L98.2Very high97.8Very high5 Ų537.6 Ų37.63%0.02620%0.2CC..Hα-helixtrans-64.6-48.1173.2-179.663.2000111.4Y187 K193 V219 M220 E259 T260 K265 S266 W267Y187-L263 HydrophobicContact CD1-CD1 3.99Å; Y187-L263 HydrophobicContact CD1-CD2 3.61Å; Y187-L263 HydrophobicContact CD1-CG 4.45Å; Y187-L263 HydrophobicContact CD2-CD2 4.04Å; Y187-L263 HydrophobicContact CE1-CD1 4.41Å; Y187-L263 HydrophobicContact CE1-CD2 4.05Å; Y187-L263 HydrophobicContact CE2-CD2 4.43Å; Y187-L263 HydrophobicContact CG-CD2 3.6Å; K193-L263 HydrophobicContact CD-CD1 4.18Å; K193-L263 HydrophobicContact CG-CD1 4.11Å; V219-L263 HydrophobicContact CB-CD2 4.24Å; V219-L263 HydrophobicContact CG2-CD2 3.84Å; M220-L263 HydrophobicContact SD-CD2 4.29Å; E259-L263 PolarHBondContact O-N 3.09Å; T260-L263 PolarHBondContact O-N 3.18Å; L263-K265 PolarHBondContact O-N 2.92Å; L263-S266 PolarHBondContact O-N 3.23Å; L263-S266 PolarHBondContact O-OG 2.77Å; L263-W267 HydrophobicContact CD1-CZ2 3.99Å; L263-W267 HydrophobicContact CD2-CH2 3.86Å; L263-W267 HydrophobicContact CD2-CZ2 3.7Å; L263-W267 HydrophobicContact CG-CH2 3.97Å; L263-W267 HydrophobicContact CG-CZ2 3.6Å; L263-W267 PolarHBondContact O-N 3.43Å
264V98.6Very high97.9Very high0 Ų035.1 Ų35.10%019%0.191CC..Hα-helixtrans-60.6-36.1176.3175.10000111.3V216 T260 S266 W267 T268 T286 Y298 V303V216-V264 HydrophobicContact CG2-CG2 3.41Å; V216-V264 VanDerWaalsContact CG2-CG2 3.41Å; T260-V264 HydrophobicContact CG2-CG2 4.5Å; T260-V264 WeakPolarHBondContact O-CG2 3.2Å; T260-V264 PolarHBondContact O-N 3.36Å; V264-S266 VanDerWaalsContact C-N 3.28Å; V264-S266 PolarHBondContact O-N 2.75Å; V264-W267 HydrophobicContact CB-CE3 4.33Å; V264-W267 HydrophobicContact CG2-CE3 3.96Å; V264-W267 HydrophobicContact CG2-CZ3 3.83Å; V264-W267 WeakPolarHBondContact O-CB 3.32Å; V264-W267 PolarHBondContact O-N 2.78Å; V264-W267 VanDerWaalsContact O-N 3.16Å; V264-T268 HydrophobicContact CG1-CG2 4.3Å; V264-T268 WeakPolarHBondContact O-CG2 3.42Å; V264-T268 PolarHBondContact O-N 3.3Å; V264-T268 PolarHBondContact O-OG1 2.92Å; V264-T286 HydrophobicContact CG1-CG2 4.05Å; V264-T286 HydrophobicContact CG2-CG2 4.49Å; V264-Y298 HydrophobicContact CG1-CD1 4.41Å; V264-Y298 HydrophobicContact CG2-CD1 4.34Å; V264-Y298 HydrophobicContact CG2-CE1 3.92Å; V264-V303 HydrophobicContact CG1-CG1 3.47Å; V264-V303 VanDerWaalsContact CG1-CG1 3.47Å
265K98.4Very high97.9Very high84 Ų8435.1 Ų35.137%0.36519%0.192SC..Hα-helixtrans-63.6-31.8176.2-167.7175.4-177.7175.40112.9Y261 E262 L263 T268 A269Y261-K265 WeakPolarHBondContact O-CB 3.34Å; Y261-K265 PolarHBondContact O-N 2.99Å; E262-K265 WeakPolarHBondContact O-CB 3.45Å; E262-K265 PolarHBondContact O-N 2.78Å; L263-K265 PolarHBondContact O-N 2.92Å; K265-T268 WeakPolarHBondContact CA-OG1 3.42Å; K265-T268 PolarHBondContact O-OG1 3.2Å; K265-T268 VanDerWaalsContact O-OG1 3.13Å; K265-A269 VanDerWaalsContact O-CB 3.32Å; K265-A269 WeakPolarHBondContact O-CB 3.4Å; K265-A269 PolarHBondContact O-N 2.88Å
266S98.3Very high97.9Very high40 Ų4041.7 Ų41.728%0.2822%0.222SC..Hα-helixtrans-66.8-40.7173.490.80000111.2E197 E262 L263 V264 A269 L270E197-S266 PolarHBondContact OE1-OG 2.87Å; E197-S266 VanDerWaalsContact OE1-OG 3.07Å; E262-S266 PolarHBondContact O-N 2.71Å; E262-S266 VanDerWaalsContact O-N 3.15Å; L263-S266 PolarHBondContact O-N 3.23Å; L263-S266 PolarHBondContact O-OG 2.77Å; V264-S266 VanDerWaalsContact C-N 3.28Å; V264-S266 PolarHBondContact O-N 2.75Å; S266-A269 PolarHBondContact O-N 3.03Å; S266-L270 PolarHBondContact O-N 2.95Å
267W98.7Very high98Very high0 Ų048.2 Ų48.20%025%0.253CS..Hα-helixtrans-66-43.9176.4-57.1-26.7000112.6P112 Y187 F200 I213 V216 V219 L263 V264 A269 L270 F271P112-W267 HydrophobicContact CB-CH2 3.6Å; P112-W267 HydrophobicContact CB-CZ2 4.07Å; P112-W267 HydrophobicContact CB-CZ3 4.34Å; P112-W267 HydrophobicContact CG-CH2 3.8Å; P112-W267 HydrophobicContact CG-CZ3 4.12Å; Y187-W267 AromaticContact CE1-CZ2 3.89Å; Y187-W267 HydrophobicContact CE1-CZ2 3.89Å; Y187-W267 AromaticContact CZ-CZ2 3.95Å; F200-W267 HydrophobicContact CD2-CG 4.48Å; F200-W267 HydrophobicContact CE2-CB 4.41Å; F200-W267 AromaticContact CE2-CD1 3.9Å; F200-W267 AromaticContact CE2-CD2 3.91Å; F200-W267 HydrophobicContact CE2-CD2 3.91Å; F200-W267 AromaticContact CE2-CG 3.83Å; F200-W267 HydrophobicContact CE2-CG 3.83Å; F200-W267 HydrophobicContact CZ-CD2 4.32Å; F200-W267 HydrophobicContact CZ-CG 4.47Å; I213-W267 HydrophobicContact CD1-CE3 4.01Å; I213-W267 HydrophobicContact CG2-CE3 4.25Å; I213-W267 HydrophobicContact CG2-CZ3 3.77Å; V216-W267 HydrophobicContact CG2-CZ3 4.24Å; V219-W267 HydrophobicContact CG1-CH2 4.36Å; L263-W267 HydrophobicContact CD1-CZ2 3.99Å; L263-W267 HydrophobicContact CD2-CH2 3.86Å; L263-W267 HydrophobicContact CD2-CZ2 3.7Å; L263-W267 HydrophobicContact CG-CH2 3.97Å; L263-W267 HydrophobicContact CG-CZ2 3.6Å; L263-W267 PolarHBondContact O-N 3.43Å; V264-W267 HydrophobicContact CB-CE3 4.33Å; V264-W267 HydrophobicContact CG2-CE3 3.96Å; V264-W267 HydrophobicContact CG2-CZ3 3.83Å; V264-W267 WeakPolarHBondContact O-CB 3.32Å; V264-W267 PolarHBondContact O-N 2.78Å; V264-W267 VanDerWaalsContact O-N 3.16Å; W267-A269 VanDerWaalsContact C-N 3.32Å; W267-A269 PolarHBondContact O-N 2.82Å; W267-L270 WeakPolarHBondContact O-CB 3.39Å; W267-L270 PolarHBondContact O-N 2.77Å; W267-F271 HydrophobicContact CB-CE1 4.46Å; W267-F271 HydrophobicContact CB-CE2 4.3Å; W267-F271 HydrophobicContact CB-CZ 4Å; W267-F271 WeakPolarHBondContact O-CD1 3.42Å; W267-F271 WeakPolarHBondContact O-CD2 3.44Å; W267-F271 WeakPolarHBondContact O-CG 3.38Å; W267-F271 PolarHBondContact O-N 2.96Å
268T98.5Very high97.9Very high5 Ų551.8 Ų51.83%0.03127%0.269CS..Hα-helixtrans-68.5-32.8178.160.60000112.2V264 K265 F271 R272 S301 V303V264-T268 HydrophobicContact CG1-CG2 4.3Å; V264-T268 WeakPolarHBondContact O-CG2 3.42Å; V264-T268 PolarHBondContact O-N 3.3Å; V264-T268 PolarHBondContact O-OG1 2.92Å; K265-T268 WeakPolarHBondContact CA-OG1 3.42Å; K265-T268 PolarHBondContact O-OG1 3.2Å; K265-T268 VanDerWaalsContact O-OG1 3.13Å; T268-F271 PolarHBondContact O-N 3.24Å; T268-R272 WeakPolarHBondContact O-CB 3.39Å; T268-R272 PolarHBondContact O-N 3Å; T268-S301 WeakPolarHBondContact CB-O 3.43Å; T268-S301 VanDerWaalsContact CG2-O 3.3Å; T268-S301 WeakPolarHBondContact CG2-O 3.48Å; T268-S301 PolarHBondContact OG1-O 2.78Å; T268-V303 HydrophobicContact CG2-CB 4.45Å; T268-V303 HydrophobicContact CG2-CG1 3.82Å
269A98.5Very high97.8Very high41 Ų4154.7 Ų54.734%0.33928%0.275SS..Hα-helixtrans-62-45.4169.900000111.7K265 S266 W267 F271 R272 S273K265-A269 VanDerWaalsContact O-CB 3.32Å; K265-A269 WeakPolarHBondContact O-CB 3.4Å; K265-A269 PolarHBondContact O-N 2.88Å; S266-A269 PolarHBondContact O-N 3.03Å; W267-A269 VanDerWaalsContact C-N 3.32Å; W267-A269 PolarHBondContact O-N 2.82Å; A269-F271 PolarHBondContact O-N 3.08Å; A269-R272 PolarHBondContact O-N 2.95Å; A269-S273 PolarHBondContact O-N 3.29Å; A269-S273 PolarHBondContact O-OG 3.19Å
270L98.6Very high97.7Very high35 Ų3553.4 Ų53.418%0.18327%0.268CS..Hα-helixtrans-57.5-46.8174.3-179.671.4000111.9E197 F200 L201 S266 W267 R272 S273 F274E197-L270 HydrophobicContact CB-CD2 3.76Å; E197-L270 HydrophobicContact CG-CD2 3.93Å; F200-L270 HydrophobicContact CB-CD2 4.33Å; L201-L270 HydrophobicContact CD1-CD1 4.1Å; L201-L270 HydrophobicContact CD2-CD1 3.92Å; L201-L270 HydrophobicContact CD2-CD2 4.44Å; L201-L270 HydrophobicContact CD2-CG 4.15Å; L201-L270 HydrophobicContact CG-CD1 4.1Å; L201-L270 HydrophobicContact CG-CD2 4.15Å; L201-L270 HydrophobicContact CG-CG 4.36Å; S266-L270 PolarHBondContact O-N 2.95Å; W267-L270 WeakPolarHBondContact O-CB 3.39Å; W267-L270 PolarHBondContact O-N 2.77Å; L270-R272 VanDerWaalsContact C-N 3.34Å; L270-R272 PolarHBondContact O-N 3.27Å; L270-S273 PolarHBondContact O-N 3.1Å; L270-F274 WeakPolarHBondContact O-CB 3.49Å; L270-F274 PolarHBondContact O-N 3.15Å
271F98.6Very high97.6Very high3 Ų354.4 Ų54.41%0.01328%0.275CS..Hα-helixtrans-61.7-41.8178.7-61.5-12.8000112F200 L204 F211 I213 W267 T268 A269 G275 I282F200-F271 HydrophobicContact CB-CE1 3.81Å; F200-F271 AromaticContact CD1-CE1 3.71Å; F200-F271 HydrophobicContact CD1-CE1 3.71Å; F200-F271 AromaticContact CD1-CZ 3.64Å; F200-F271 HydrophobicContact CD1-CZ 3.64Å; F200-F271 HydrophobicContact CD2-CE1 4.14Å; F200-F271 HydrophobicContact CD2-CZ 4.28Å; F200-F271 HydrophobicContact CE1-CE1 4.23Å; F200-F271 AromaticContact CE1-CZ 3.69Å; F200-F271 HydrophobicContact CE1-CZ 3.69Å; F200-F271 HydrophobicContact CE2-CZ 4.35Å; F200-F271 AromaticContact CG-CE1 3.64Å; F200-F271 HydrophobicContact CG-CE1 3.64Å; F200-F271 AromaticContact CG-CZ 3.94Å; F200-F271 HydrophobicContact CG-CZ 3.94Å; F200-F271 HydrophobicContact CZ-CZ 4.07Å; L204-F271 HydrophobicContact CD1-CD1 4.06Å; F211-F271 HydrophobicContact CD2-CD1 4.42Å; F211-F271 AromaticContact CD2-CE1 3.81Å; F211-F271 HydrophobicContact CD2-CE1 3.81Å; F211-F271 HydrophobicContact CD2-CE2 4.02Å; F211-F271 AromaticContact CD2-CZ 3.57Å; F211-F271 HydrophobicContact CD2-CZ 3.57Å; F211-F271 HydrophobicContact CE2-CD1 4.36Å; F211-F271 AromaticContact CE2-CE1 3.87Å; F211-F271 HydrophobicContact CE2-CE1 3.87Å; F211-F271 HydrophobicContact CE2-CZ 4.13Å; F211-F271 HydrophobicContact CG-CZ 4.42Å; I213-F271 HydrophobicContact CD1-CE2 4.41Å; W267-F271 HydrophobicContact CB-CE1 4.46Å; W267-F271 HydrophobicContact CB-CE2 4.3Å; W267-F271 HydrophobicContact CB-CZ 4Å; W267-F271 WeakPolarHBondContact O-CD1 3.42Å; W267-F271 WeakPolarHBondContact O-CD2 3.44Å; W267-F271 WeakPolarHBondContact O-CG 3.38Å; W267-F271 PolarHBondContact O-N 2.96Å; T268-F271 PolarHBondContact O-N 3.24Å; A269-F271 PolarHBondContact O-N 3.08Å; F271-G275 PolarHBondContact O-N 2.99Å; F271-I282 HydrophobicContact CB-CB 3.91Å; F271-I282 HydrophobicContact CB-CG2 3.67Å; F271-I282 HydrophobicContact CD1-CG2 4.45Å; F271-I282 HydrophobicContact CD2-CG2 4.32Å; F271-I282 HydrophobicContact CG-CG2 3.89Å; F271-I282 VanDerWaalsContact O-CG1 3.29Å; F271-I282 WeakPolarHBondContact O-CG1 3.28Å
272R97.8Very high97.6Very high104 Ų10454 Ų5439%0.39227%0.274SS..Hα-helixtrans-63-49.5176.1-175-174.6-63.7109.5-10.8111.3T268 A269 L270 F274 G275 E276 D302T268-R272 WeakPolarHBondContact O-CB 3.39Å; T268-R272 PolarHBondContact O-N 3Å; A269-R272 PolarHBondContact O-N 2.95Å; L270-R272 VanDerWaalsContact C-N 3.34Å; L270-R272 PolarHBondContact O-N 3.27Å; R272-F274 VanDerWaalsContact C-N 3.34Å; R272-F274 PolarHBondContact O-N 3.45Å; R272-G275 WeakPolarHBondContact O-CA 3.21Å; R272-G275 PolarHBondContact O-N 2.84Å; R272-G275 VanDerWaalsContact O-N 3.12Å; R272-E276 HydrophobicContact CG-CG 4.48Å; R272-E276 WeakPolarHBondContact CG-OE1 3.18Å; R272-E276 WeakPolarHBondContact O-CG 3.4Å; R272-E276 PolarHBondContact O-N 3.41Å; R272-D302 IonicContact CZ-OD2 3.82Å; R272-D302 VanDerWaalsContact NH2-CG 3.34Å; R272-D302 IonicContact NH2-OD2 2.84Å; R272-D302 PolarHBondContact NH2-OD2 3.05Å
273S98.2Very high97.7Very high71 Ų7148.1 Ų48.150%0.49725%0.247SC..Hα-helixtrans-61-42.3179.1-64.70000112.2A269 L270 Q277A269-S273 PolarHBondContact O-N 3.29Å; A269-S273 PolarHBondContact O-OG 3.19Å; L270-S273 PolarHBondContact O-N 3.1Å; S273-Q277 WeakPolarHBondContact O-CB 3.16Å; S273-Q277 PolarHBondContact O-N 3.21Å; S273-Q277 VanDerWaalsContact O-N 3.09Å
274F98.4Very high97.7Very high13 Ų1348 Ų486%0.05725%0.247CC..Hα-helixtrans-61.7-45.3173.1-172.7-86000111.3L201 L204 R205 L270 R272 E276 Q277 H278 I282L201-F274 HydrophobicContact CD2-CB 4.46Å; L201-F274 HydrophobicContact CD2-CD2 3.71Å; L201-F274 HydrophobicContact CD2-CE2 4.42Å; L201-F274 HydrophobicContact CD2-CG 4.42Å; L204-F274 HydrophobicContact CB-CD1 3.94Å; L204-F274 HydrophobicContact CB-CD2 4.29Å; L204-F274 HydrophobicContact CB-CE1 3.66Å; L204-F274 HydrophobicContact CB-CE2 4.02Å; L204-F274 HydrophobicContact CB-CG 4.26Å; L204-F274 HydrophobicContact CB-CZ 3.7Å; L204-F274 HydrophobicContact CD1-CB 4.16Å; L204-F274 HydrophobicContact CD1-CD1 4Å; L204-F274 HydrophobicContact CD1-CD2 4.42Å; L204-F274 HydrophobicContact CD1-CG 3.92Å; L204-F274 HydrophobicContact CG-CD1 4.4Å; L204-F274 WeakPolarHBondContact O-CZ 3.44Å; R205-F274 HydrophobicContact CG-CE2 3.98Å; R205-F274 HydrophobicContact CG-CZ 4.33Å; L270-F274 WeakPolarHBondContact O-CB 3.49Å; L270-F274 PolarHBondContact O-N 3.15Å; R272-F274 VanDerWaalsContact C-N 3.34Å; R272-F274 PolarHBondContact O-N 3.45Å; F274-E276 PolarHBondContact O-N 3.18Å; F274-Q277 PolarHBondContact O-N 2.77Å; F274-H278 AromaticContact CD1-CD2 3.89Å; F274-H278 AromaticContact CD2-CD2 3.9Å; F274-H278 HydrophobicContact CE1-CB 4.4Å; F274-H278 AromaticContact CE1-CD2 3.61Å; F274-H278 AromaticContact CE2-CD2 3.65Å; F274-H278 AromaticContact CE2-NE2 3.56Å; F274-H278 AromaticContact CZ-CD2 3.49Å; F274-H278 VanDerWaalsContact CZ-CD2 3.49Å; F274-H278 WeakPolarHBondContact CZ-CD2 3.36Å; F274-H278 AromaticContact CZ-NE2 3.62Å; F274-H278 WeakPolarHBondContact O-CB 3.41Å; F274-H278 PolarHBondContact O-CD2 3.07Å; F274-H278 VanDerWaalsContact O-CD2 3.24Å; F274-H278 PolarHBondContact O-N 2.87Å; F274-I282 HydrophobicContact CD1-CD1 4.18Å; F274-I282 HydrophobicContact CD1-CG1 4.34Å
275G97.7Very high97.7Very high5 Ų548 Ų485%0.05225%0.247CC..Hα-helixtrans-59.1-46178.100000113.5F271 R272 H278 N279 K280F271-G275 PolarHBondContact O-N 2.99Å; R272-G275 WeakPolarHBondContact O-CA 3.21Å; R272-G275 PolarHBondContact O-N 2.84Å; R272-G275 VanDerWaalsContact O-N 3.12Å; G275-H278 CarbonylContact O-C 3.53Å; G275-H278 PolarHBondContact O-N 3.05Å; G275-N279 CarbonylContact O-C 3.49Å; G275-N279 WeakPolarHBondContact O-CA 3.46Å; G275-N279 PolarHBondContact O-N 3.1Å; G275-K280 CarbonylContact C-O 3.58Å; G275-K280 WeakPolarHBondContact CA-O 3.41Å; G275-K280 PolarHBondContact O-N 2.79Å; G275-K280 VanDerWaalsContact O-O 3.12Å
276E96.9Very high97.7Very high140 Ų14044.1 Ų44.165%0.65423%0.23SC*.Hα-helixtrans-61.1-44.9176.5-73.2170.2-177.900111.9R272 F274 H278 N279R272-E276 HydrophobicContact CG-CG 4.48Å; R272-E276 WeakPolarHBondContact CG-OE1 3.18Å; R272-E276 WeakPolarHBondContact O-CG 3.4Å; R272-E276 PolarHBondContact O-N 3.41Å; F274-E276 PolarHBondContact O-N 3.18Å; E276-H278 VanDerWaalsContact C-N 3.27Å; E276-H278 PolarHBondContact O-N 3.48Å; E276-N279 PolarHBondContact O-N 3.15Å
277Q97.3Very high97.6Very high153 Ų15342.8 Ų42.872%0.71522%0.219SC*.Hα-helixtrans-61.5-35.6177.4179.1179.3-10.900112.6S273 F274S273-Q277 WeakPolarHBondContact O-CB 3.16Å; S273-Q277 PolarHBondContact O-N 3.21Å; S273-Q277 VanDerWaalsContact O-N 3.09Å; F274-Q277 PolarHBondContact O-N 2.77Å
278H96.5Very high97.3Very high96 Ų9643.1 Ų43.144%0.44422%0.223SC..Hα-helixtrans-103.97.2-175.2-70.3-82.8000113.9F274 G275 E276 K280F274-H278 AromaticContact CD1-CD2 3.89Å; F274-H278 AromaticContact CD2-CD2 3.9Å; F274-H278 HydrophobicContact CE1-CB 4.4Å; F274-H278 AromaticContact CE1-CD2 3.61Å; F274-H278 AromaticContact CE2-CD2 3.65Å; F274-H278 AromaticContact CE2-NE2 3.56Å; F274-H278 AromaticContact CZ-CD2 3.49Å; F274-H278 VanDerWaalsContact CZ-CD2 3.49Å; F274-H278 WeakPolarHBondContact CZ-CD2 3.36Å; F274-H278 AromaticContact CZ-NE2 3.62Å; F274-H278 WeakPolarHBondContact O-CB 3.41Å; F274-H278 PolarHBondContact O-CD2 3.07Å; F274-H278 VanDerWaalsContact O-CD2 3.24Å; F274-H278 PolarHBondContact O-N 2.87Å; G275-H278 CarbonylContact O-C 3.53Å; G275-H278 PolarHBondContact O-N 3.05Å; E276-H278 VanDerWaalsContact C-N 3.27Å; E276-H278 PolarHBondContact O-N 3.48Å; H278-K280 HydrophobicContact CB-CG 4.15Å; H278-K280 PolarHBondContact O-N 2.85Å
279N94.9Very high97Very high131 Ų13146.6 Ų46.670%0.70124%0.236SC*.THydrogen-bonded Turntrans50.840.3-176.2-167.240.8000113.6C13 G275 E276C13-N279 PolarHBondContact SG-O 2.81Å; G275-N279 CarbonylContact O-C 3.49Å; G275-N279 WeakPolarHBondContact O-CA 3.46Å; G275-N279 PolarHBondContact O-N 3.1Å; E276-N279 PolarHBondContact O-N 3.15Å
280K94.8Very high96.8Very high46 Ų4645.7 Ų45.720%0.223%0.226CC..  trans-130.2151.1175.864.1166171.8165.40112.5C13 V208 G275 H278 I282C13-K280 VanDerWaalsContact SG-C 3.53Å; C13-K280 WeakPolarHBondContact SG-CA 3.31Å; V208-K280 PolarHBondContact O-NZ 2.89Å; G275-K280 CarbonylContact C-O 3.58Å; G275-K280 WeakPolarHBondContact CA-O 3.41Å; G275-K280 PolarHBondContact O-N 2.79Å; G275-K280 VanDerWaalsContact O-O 3.12Å; H278-K280 HydrophobicContact CB-CG 4.15Å; H278-K280 PolarHBondContact O-N 2.85Å; K280-I282 HydrophobicContact CD-CD1 3.74Å; K280-I282 HydrophobicContact CG-CD1 3.86Å
281S95.8Very high96.5Very high21 Ų2146 Ų4615%0.14723%0.228CC..PPolyproline II helixtrans-88.5123.9170.9-64.80000110.1C13 R14 W16C13-S281 WeakPolarHBondContact CB-OG 3.47Å; C13-S281 PolarHBondContact O-OG 2.75Å; C13-S281 PolarHBondContact SG-N 2.78Å; C13-S281 VanDerWaalsContact SG-N 3.37Å; R14-S281 PolarHBondContact O-OG 3.05Å; W16-S281 PolarHBondContact NE1-O 3.19Å
282I98.2Very high96.3Very high17 Ų1748 Ų489%0.08724%0.239CC..PPolyproline II helixtrans-94.5121.7175.4-54.2-52.3000109.6L204 D209 F271 F274 K280L204-I282 HydrophobicContact CD2-CD1 3.84Å; L204-I282 HydrophobicContact CD2-CG1 4.29Å; L204-I282 HydrophobicContact CD2-CG2 3.84Å; D209-I282 WeakPolarHBondContact O-CA 3.5Å; F271-I282 HydrophobicContact CB-CB 3.91Å; F271-I282 HydrophobicContact CB-CG2 3.67Å; F271-I282 HydrophobicContact CD1-CG2 4.45Å; F271-I282 HydrophobicContact CD2-CG2 4.32Å; F271-I282 HydrophobicContact CG-CG2 3.89Å; F271-I282 VanDerWaalsContact O-CG1 3.29Å; F271-I282 WeakPolarHBondContact O-CG1 3.28Å; F274-I282 HydrophobicContact CD1-CD1 4.18Å; F274-I282 HydrophobicContact CD1-CG1 4.34Å; K280-I282 HydrophobicContact CD-CD1 3.74Å; K280-I282 HydrophobicContact CG-CD1 3.86Å
283F98.4Very high96.2Very high0 Ų048.6 Ų48.60%025%0.246CC..EExtended strand (participates in β ladder)trans-81.3143.8179.3175.2-95.8000111.7W16 W17 I22 V107 D209 G210 F211 M285 T304 F305W16-F283 HydrophobicContact CH2-CB 3.49Å; W16-F283 VanDerWaalsContact CH2-CB 3.49Å; W16-F283 HydrophobicContact CH2-CD1 4.15Å; W16-F283 HydrophobicContact CH2-CD2 4.14Å; W16-F283 AromaticContact CH2-CG 3.67Å; W16-F283 HydrophobicContact CH2-CG 3.67Å; W16-F283 HydrophobicContact CZ2-CB 3.22Å; W16-F283 AromaticContact CZ2-CG 3.95Å; W16-F283 HydrophobicContact CZ2-CG 3.95Å; W17-F283 HydrophobicContact CB-CD2 3.79Å; W17-F283 HydrophobicContact CB-CE2 3.97Å; W17-F283 AromaticContact CD2-CD2 3.9Å; W17-F283 HydrophobicContact CD2-CD2 3.9Å; W17-F283 HydrophobicContact CE3-CB 4.04Å; W17-F283 AromaticContact CE3-CD2 3.83Å; W17-F283 HydrophobicContact CE3-CD2 3.83Å; W17-F283 HydrophobicContact CE3-CG 4.44Å; W17-F283 AromaticContact CG-CD2 3.89Å; W17-F283 HydrophobicContact CG-CD2 3.89Å; W17-F283 HydrophobicContact CG-CE2 4.2Å; W17-F283 HydrophobicContact CZ3-CB 4.33Å; I22-F283 HydrophobicContact CD1-CD1 4.46Å; I22-F283 HydrophobicContact CD1-CE1 3.64Å; I22-F283 HydrophobicContact CD1-CE2 3.95Å; I22-F283 HydrophobicContact CD1-CZ 3.35Å; V107-F283 HydrophobicContact CG1-CD1 4.21Å; V107-F283 HydrophobicContact CG1-CE1 4.39Å; V107-F283 HydrophobicContact CG2-CD1 3.75Å; V107-F283 HydrophobicContact CG2-CE1 4.32Å; D209-F283 PolarHBondContact O-N 3.13Å; G210-F283 CarbonylContact C-O 3.5Å; G210-F283 WeakPolarHBondContact CA-O 3.4Å; F211-F283 PolarHBondContact N-O 3.46Å; F283-M285 HydrophobicContact CE1-CB 3.85Å; F283-M285 HydrophobicContact CE1-CE 4.28Å; F283-M285 HydrophobicContact CE1-CG 3.63Å; F283-M285 HydrophobicContact CE1-SD 3.65Å; F283-M285 HydrophobicContact CZ-CB 3.79Å; F283-M285 HydrophobicContact CZ-CG 3.98Å; F283-M285 HydrophobicContact CZ-SD 3.77Å; F283-T304 HydrophobicContact CD2-CG2 3.68Å; F283-T304 HydrophobicContact CE2-CG2 3.63Å; F283-F305 HydrophobicContact CE2-CD1 4.26Å; F283-F305 AromaticContact CE2-CE1 3.54Å; F283-F305 HydrophobicContact CE2-CE1 3.54Å; F283-F305 HydrophobicContact CE2-CE2 4.32Å; F283-F305 AromaticContact CE2-CZ 3.58Å; F283-F305 HydrophobicContact CE2-CZ 3.58Å; F283-F305 AromaticContact CZ-CE1 3.87Å; F283-F305 HydrophobicContact CZ-CE1 3.87Å; F283-F305 AromaticContact CZ-CE2 3.81Å; F283-F305 HydrophobicContact CZ-CE2 3.81Å; F283-F305 AromaticContact CZ-CZ 3.39Å; F283-F305 HydrophobicContact CZ-CZ 3.39Å
284S98.5Very high96.1Very high4 Ų447.8 Ų47.83%0.02823%0.234CC..EExtended strand (participates in β ladder)trans-142.2128.8172.851.30000111.2F211 V303 T304 F305F211-S284 WeakPolarHBondContact O-CA 3.35Å; S284-V303 WeakPolarHBondContact OG-CA 3.31Å; S284-T304 PolarHBondContact N-OG1 3.44Å; S284-T304 WeakPolarHBondContact O-CA 3.42Å; S284-T304 WeakPolarHBondContact O-CB 3.42Å; S284-T304 PolarHBondContact O-N 3.09Å; S284-T304 PolarHBondContact O-OG1 2.65Å; S284-T304 PolarHBondContact OG-N 3.08Å; S284-F305 PolarHBondContact O-N 3.19Å
285M98.2Very high96Very high0 Ų047.8 Ų47.80%024%0.235CC..EExtended strand (participates in β ladder)trans-129.1142.216865.9-173174.800111.1I22 W60 V107 F211 R212 I213 F283 F305 L307I22-M285 HydrophobicContact CD1-SD 4.36Å; W60-M285 HydrophobicContact CB-CE 4.34Å; W60-M285 HydrophobicContact CD2-CE 3.48Å; W60-M285 VanDerWaalsContact CD2-CE 3.48Å; W60-M285 HydrophobicContact CE3-CE 3.36Å; W60-M285 HydrophobicContact CG-CE 3.91Å; W60-M285 HydrophobicContact CH2-CE 4.38Å; W60-M285 HydrophobicContact CZ3-CE 3.83Å; V107-M285 HydrophobicContact CG1-CE 4.42Å; F211-M285 PolarHBondContact O-N 3.29Å; R212-M285 CarbonylContact C-O 3.6Å; R212-M285 WeakPolarHBondContact CA-O 3.47Å; R212-M285 HydrophobicContact CB-CE 3.52Å; R212-M285 HydrophobicContact CB-CG 3.91Å; R212-M285 HydrophobicContact CG-CE 3.74Å; R212-M285 HydrophobicContact CG-CG 3.95Å; I213-M285 PolarHBondContact N-O 2.89Å; F283-M285 HydrophobicContact CE1-CB 3.85Å; F283-M285 HydrophobicContact CE1-CE 4.28Å; F283-M285 HydrophobicContact CE1-CG 3.63Å; F283-M285 HydrophobicContact CE1-SD 3.65Å; F283-M285 HydrophobicContact CZ-CB 3.79Å; F283-M285 HydrophobicContact CZ-CG 3.98Å; F283-M285 HydrophobicContact CZ-SD 3.77Å; M285-F305 WeakPolarHBondContact CA-O 3.45Å; M285-F305 HydrophobicContact CB-CD2 4.03Å; M285-F305 HydrophobicContact CB-CE2 3.92Å; M285-F305 VanDerWaalsContact CB-O 3.27Å; M285-F305 WeakPolarHBondContact CB-O 3.18Å; M285-F305 HydrophobicContact SD-CE2 3.98Å; M285-L307 HydrophobicContact CG-CG 4.4Å; M285-L307 HydrophobicContact SD-CD1 4.28Å; M285-L307 HydrophobicContact SD-CD2 3.76Å; M285-L307 HydrophobicContact SD-CG 4.07Å
286T98.6Very high96Very high1 Ų148.4 Ų48.41%0.00624%0.237CC..EExtended strand (participates in β ladder)trans-101.6148.9175.845.30000110.8I213 V216 V264 Y298 V303 P306 L307I213-T286 HydrophobicContact CB-CG2 4.21Å; I213-T286 HydrophobicContact CD1-CG2 4.2Å; V216-T286 HydrophobicContact CB-CG2 4.41Å; V216-T286 HydrophobicContact CG1-CG2 3.85Å; V216-T286 HydrophobicContact CG2-CG2 4.27Å; V264-T286 HydrophobicContact CG1-CG2 4.05Å; V264-T286 HydrophobicContact CG2-CG2 4.49Å; T286-Y298 HydrophobicContact CG2-CD1 3.96Å; T286-Y298 HydrophobicContact CG2-CE1 4.19Å; T286-V303 HydrophobicContact CG2-CG1 3.84Å; T286-P306 WeakPolarHBondContact OG1-CA 3.05Å; T286-P306 WeakPolarHBondContact OG1-CB 3.28Å; T286-L307 WeakPolarHBondContact O-CB 3.49Å; T286-L307 PolarHBondContact O-N 2.98Å
287E97Very high96Very high13 Ų1344.8 Ų44.86%0.06122%0.222CC..  trans-116127.2172.4-176.3-87.6143.900111.7R212 I213 A215 V216 Y289 L307 F309R212-E287 IonicContact CZ-OE2 3.38Å; R212-E287 VanDerWaalsContact NH2-CB 3.3Å; R212-E287 IonicContact NH2-OE2 3.74Å; R212-E287 PolarHBondContact NH2-OE2 3.08Å; I213-E287 PolarHBondContact O-N 2.89Å; A215-E287 PolarHBondContact N-OE2 2.86Å; V216-E287 WeakPolarHBondContact CG1-O 3.47Å; V216-E287 PolarHBondContact N-O 2.81Å; E287-Y289 WeakPolarHBondContact OE1-CD2 3.4Å; E287-Y289 WeakPolarHBondContact OE1-CE2 3.43Å; E287-L307 HydrophobicContact CB-CD1 4.09Å; E287-L307 HydrophobicContact CG-CD1 4.34Å; E287-F309 HydrophobicContact CG-CE2 3.51Å; E287-F309 HydrophobicContact CG-CZ 3.45Å; E287-F309 VanDerWaalsContact CG-CZ 3.45Å
288G92.4Very high96.1Very high7 Ų737.6 Ų37.67%0.07219%0.189CC..  trans-157.1117.9176.700000111.4T290G288-T290 VanDerWaalsContact C-N 3.29Å; G288-T290 PolarHBondContact O-N 2.94Å; G288-T290 VanDerWaalsContact O-N 3.1Å
289Y91.1Very high96.1Very high77 Ų7733 Ų3330%0.30217%0.168SC..  trans-79.280.1165.2-70.2-85.6000110E287 F309 N346E287-Y289 WeakPolarHBondContact OE1-CD2 3.4Å; E287-Y289 WeakPolarHBondContact OE1-CE2 3.43Å; Y289-F309 AromaticContact CD1-CD2 3.79Å; Y289-F309 HydrophobicContact CD1-CD2 3.79Å; Y289-F309 HydrophobicContact CD1-CE2 4.26Å; Y289-F309 HydrophobicContact CD1-CG 4.45Å; Y289-F309 HydrophobicContact CD2-CD2 4.37Å; Y289-F309 HydrophobicContact CD2-CE2 4.06Å; Y289-F309 HydrophobicContact CE1-CB 4.36Å; Y289-F309 AromaticContact CE1-CD2 3.7Å; Y289-F309 HydrophobicContact CE1-CD2 3.7Å; Y289-F309 HydrophobicContact CE1-CE2 4.02Å; Y289-F309 HydrophobicContact CE1-CG 4.07Å; Y289-F309 HydrophobicContact CE2-CD2 4.29Å; Y289-F309 AromaticContact CE2-CE2 3.81Å; Y289-F309 HydrophobicContact CE2-CE2 3.81Å; Y289-F309 HydrophobicContact CE2-CZ 4.35Å; Y289-F309 HydrophobicContact CG-CD2 4.15Å; Y289-F309 HydrophobicContact CG-CE2 4.28Å; Y289-F309 AromaticContact CZ-CD2 3.97Å; Y289-F309 AromaticContact CZ-CE2 3.79Å; Y289-N346 PolarHBondContact OH-ND2 2.65Å
290T94.4Very high96.2Very high23 Ų2331.6 Ų31.614%0.14116%0.16CC..SBendtrans-134.8-178.3175.2-176.60000109.9I217 H242 D256 G288 H294 V295I217-T290 HydrophobicContact CG2-CG2 4.04Å; H242-T290 PolarHBondContact NE2-OG1 3.28Å; D256-T290 WeakPolarHBondContact OD2-CB 3.49Å; D256-T290 PolarHBondContact OD2-OG1 2.95Å; G288-T290 VanDerWaalsContact C-N 3.29Å; G288-T290 PolarHBondContact O-N 2.94Å; G288-T290 VanDerWaalsContact O-N 3.1Å; T290-H294 HydrophobicContact CG2-CB 3.6Å; T290-V295 HydrophobicContact CG2-CG2 3.75Å
291D93.7Very high96.3Very high42 Ų4229.5 Ų29.523%0.22515%0.151CC..  trans-68.2167.7176.270.517.2000113T241 E293 H294 V295T241-D291 HydrophobicContact CG2-CB 3.77Å; D291-E293 PolarHBondContact O-N 3.41Å; D291-E293 PolarHBondContact OD1-N 3.36Å; D291-E293 VanDerWaalsContact OD1-N 3.15Å; D291-H294 VanDerWaalsContact CG-ND1 3.33Å; D291-H294 PolarHBondContact O-N 3.01Å; D291-H294 IonicContact OD1-CE1 3.66Å; D291-H294 IonicContact OD1-CG 3.52Å; D291-H294 PolarHBondContact OD1-N 3.09Å; D291-H294 IonicContact OD1-ND1 2.94Å; D291-H294 PolarHBondContact OD1-ND1 3.18Å; D291-H294 IonicContact OD2-CE1 3.92Å; D291-H294 IonicContact OD2-ND1 2.98Å; D291-H294 PolarHBondContact OD2-ND1 2.78Å; D291-V295 VanDerWaalsContact O-CG2 3.27Å; D291-V295 WeakPolarHBondContact O-CG2 3.31Å; D291-V295 PolarHBondContact O-N 3.38Å; D291-V295 VanDerWaalsContact O-N 3.08Å
292L94.3Very high96.3Very high45 Ų4531.4 Ų31.424%0.23616%0.159CC..Hα-helixtrans-65.4-23.7-177.6-177.856.1000112.7I296 N329 W330 K333L292-I296 HydrophobicContact CD1-CD1 4.2Å; L292-I296 HydrophobicContact CD1-CG1 3.81Å; L292-I296 HydrophobicContact CG-CG1 4.22Å; L292-I296 WeakPolarHBondContact O-CB 3.41Å; L292-I296 WeakPolarHBondContact O-CG1 3.33Å; L292-I296 PolarHBondContact O-N 3.1Å; L292-I296 VanDerWaalsContact O-N 3.14Å; L292-N329 HydrophobicContact CD2-CB 4.08Å; L292-W330 HydrophobicContact CD1-CE3 3.54Å; L292-W330 HydrophobicContact CD1-CZ3 3.81Å; L292-K333 HydrophobicContact CD2-CD 3.63Å; L292-K333 HydrophobicContact CG-CD 3.77Å
293E94.8Very high96.3Very high115 Ų11530.8 Ų30.854%0.53716%0.157SC..Hα-helixtrans-72-52.1179.5-82.2141-145.100110.6D291 V295 I296 D297 K333D291-E293 PolarHBondContact O-N 3.41Å; D291-E293 PolarHBondContact OD1-N 3.36Å; D291-E293 VanDerWaalsContact OD1-N 3.15Å; E293-V295 VanDerWaalsContact C-N 3.32Å; E293-V295 PolarHBondContact O-N 2.96Å; E293-I296 PolarHBondContact O-N 3.46Å; E293-I296 VanDerWaalsContact O-N 3.1Å; E293-D297 PolarHBondContact O-N 3.07Å; E293-D297 VanDerWaalsContact O-N 3.11Å; E293-K333 IonicContact OE1-NZ 2.71Å; E293-K333 PolarHBondContact OE1-NZ 3.04Å
294H96Very high96.3Very high54 Ų5431.8 Ų31.825%0.2516%0.162CC..Hα-helixtrans-63.9-37177.3-65.192.1000112.2D256 Y261 T290 D291 I296 D297 Y298D256-H294 IonicContact OD2-CD2 3.47Å; D256-H294 IonicContact OD2-CG 3.9Å; Y261-H294 WeakPolarHBondContact OH-CA 3.17Å; Y261-H294 PolarHBondContact OH-CD2 2.76Å; Y261-H294 PolarHBondContact OH-O 3.4Å; T290-H294 HydrophobicContact CG2-CB 3.6Å; D291-H294 VanDerWaalsContact CG-ND1 3.33Å; D291-H294 PolarHBondContact O-N 3.01Å; D291-H294 IonicContact OD1-CE1 3.66Å; D291-H294 IonicContact OD1-CG 3.52Å; D291-H294 PolarHBondContact OD1-N 3.09Å; D291-H294 IonicContact OD1-ND1 2.94Å; D291-H294 PolarHBondContact OD1-ND1 3.18Å; D291-H294 IonicContact OD2-CE1 3.92Å; D291-H294 IonicContact OD2-ND1 2.98Å; D291-H294 PolarHBondContact OD2-ND1 2.78Å; H294-I296 VanDerWaalsContact C-N 3.33Å; H294-I296 PolarHBondContact O-N 2.73Å; H294-D297 PolarHBondContact O-N 2.69Å; H294-Y298 WeakPolarHBondContact O-CD2 3.31Å
295V97.3Very high96.3Very high13 Ų1331.6 Ų31.68%0.07916%0.161CC..Hα-helixtrans-59.5-44.7173.2171.20000110.7T290 D291 E293 D297 Y298 P306 W330T290-V295 HydrophobicContact CG2-CG2 3.75Å; D291-V295 VanDerWaalsContact O-CG2 3.27Å; D291-V295 WeakPolarHBondContact O-CG2 3.31Å; D291-V295 PolarHBondContact O-N 3.38Å; D291-V295 VanDerWaalsContact O-N 3.08Å; E293-V295 VanDerWaalsContact C-N 3.32Å; E293-V295 PolarHBondContact O-N 2.96Å; V295-D297 VanDerWaalsContact C-N 3.32Å; V295-D297 PolarHBondContact O-N 2.84Å; V295-Y298 PolarHBondContact O-N 3.07Å; V295-P306 HydrophobicContact CG1-CB 3.92Å; V295-P306 HydrophobicContact CG1-CG 3.91Å; V295-P306 WeakPolarHBondContact O-CB 3.43Å; V295-P306 WeakPolarHBondContact O-CG 3.35Å; V295-W330 HydrophobicContact CG1-CH2 4.13Å; V295-W330 HydrophobicContact CG1-CZ3 3.81Å
296I97.4Very high96.3Very high18 Ų1831.7 Ų31.79%0.09216%0.162CC..Hα-helixtrans-67.6-33.7-177.1-70.8-75.8000111.9L292 E293 H294 Y298 Y299 W330 K333 K334L292-I296 HydrophobicContact CD1-CD1 4.2Å; L292-I296 HydrophobicContact CD1-CG1 3.81Å; L292-I296 HydrophobicContact CG-CG1 4.22Å; L292-I296 WeakPolarHBondContact O-CB 3.41Å; L292-I296 WeakPolarHBondContact O-CG1 3.33Å; L292-I296 PolarHBondContact O-N 3.1Å; L292-I296 VanDerWaalsContact O-N 3.14Å; E293-I296 PolarHBondContact O-N 3.46Å; E293-I296 VanDerWaalsContact O-N 3.1Å; H294-I296 VanDerWaalsContact C-N 3.33Å; H294-I296 PolarHBondContact O-N 2.73Å; I296-Y298 PolarHBondContact O-N 3.31Å; I296-Y299 HydrophobicContact CD1-CD2 4.37Å; I296-Y299 HydrophobicContact CD1-CE2 4.14Å; I296-Y299 WeakPolarHBondContact O-CB 3.41Å; I296-Y299 WeakPolarHBondContact O-CD2 3.26Å; I296-Y299 PolarHBondContact O-N 2.92Å; I296-W330 HydrophobicContact CD1-CE3 4.4Å; I296-W330 HydrophobicContact CD1-CH2 4.48Å; I296-W330 HydrophobicContact CD1-CZ3 4.2Å; I296-K333 HydrophobicContact CD1-CB 4.17Å; I296-K333 HydrophobicContact CG1-CB 4.12Å; I296-K334 HydrophobicContact CD1-CB 4.2Å
297D97.1Very high96.2Very high65 Ų6531.7 Ų31.735%0.34816%0.162SC..Hα-helixtrans-61.6-25.2-180-79.8-23000113.7Y261 E293 H294 V295 Y299 N300Y261-D297 HydrophobicContact CD1-CB 4.19Å; Y261-D297 HydrophobicContact CE1-CB 3.61Å; Y261-D297 HydrophobicContact CE2-CB 4.36Å; E293-D297 PolarHBondContact O-N 3.07Å; E293-D297 VanDerWaalsContact O-N 3.11Å; H294-D297 PolarHBondContact O-N 2.69Å; V295-D297 VanDerWaalsContact C-N 3.32Å; V295-D297 PolarHBondContact O-N 2.84Å; D297-Y299 PolarHBondContact O-N 2.57Å; D297-Y299 VanDerWaalsContact O-N 3.13Å; D297-N300 WeakPolarHBondContact O-CB 3.44Å; D297-N300 PolarHBondContact O-N 2.93Å; D297-N300 PolarHBondContact O-ND2 2.9Å
298Y98.1Very high96.2Very high2 Ų231.3 Ų31.31%0.00816%0.16CC..G310 helixtrans-60.2-23.5173.4-79-72.1000113.8V216 I217 T260 Y261 V264 T286 H294 V295 I296 N300 S301 V303 P306V216-Y298 HydrophobicContact CG1-CE1 3.86Å; V216-Y298 HydrophobicContact CG1-CE2 4.23Å; V216-Y298 VanDerWaalsContact CG1-OH 3.24Å; V216-Y298 WeakPolarHBondContact CG1-OH 3.4Å; V216-Y298 HydrophobicContact CG2-CE1 4.06Å; I217-Y298 HydrophobicContact CG2-CE2 4.29Å; T260-Y298 HydrophobicContact CG2-CE1 4.03Å; T260-Y298 WeakPolarHBondContact CG2-OH 3.1Å; Y261-Y298 AromaticContact CD1-CD1 3.9Å; Y261-Y298 HydrophobicContact CD1-CD1 3.9Å; Y261-Y298 AromaticContact CD1-CE1 3.99Å; Y261-Y298 HydrophobicContact CD1-CE1 3.99Å; Y261-Y298 HydrophobicContact CD1-CG 4.21Å; Y261-Y298 HydrophobicContact CE1-CD1 4.09Å; Y261-Y298 AromaticContact CE1-CD2 3.96Å; Y261-Y298 HydrophobicContact CE1-CD2 3.96Å; Y261-Y298 HydrophobicContact CE1-CE1 4.05Å; Y261-Y298 AromaticContact CE1-CE2 3.95Å; Y261-Y298 HydrophobicContact CE1-CE2 3.95Å; Y261-Y298 HydrophobicContact CE1-CG 4.04Å; Y261-Y298 AromaticContact CE1-CZ 3.99Å; V264-Y298 HydrophobicContact CG1-CD1 4.41Å; V264-Y298 HydrophobicContact CG2-CD1 4.34Å; V264-Y298 HydrophobicContact CG2-CE1 3.92Å; T286-Y298 HydrophobicContact CG2-CD1 3.96Å; T286-Y298 HydrophobicContact CG2-CE1 4.19Å; H294-Y298 WeakPolarHBondContact O-CD2 3.31Å; V295-Y298 PolarHBondContact O-N 3.07Å; I296-Y298 PolarHBondContact O-N 3.31Å; Y298-N300 PolarHBondContact O-N 2.87Å; Y298-S301 WeakPolarHBondContact O-CA 3.47Å; Y298-S301 WeakPolarHBondContact O-CB 3.41Å; Y298-S301 PolarHBondContact O-N 2.95Å; Y298-V303 WeakPolarHBondContact O-CG2 3.49Å; Y298-P306 HydrophobicContact CD2-CB 4.37Å; Y298-P306 HydrophobicContact CG-CB 4.39Å
299Y97.7Very high96.4Very high0 Ų032.4 Ų32.40%016%0.163CC..G310 helixtrans-62-23.1172.1-77.6-66.4000113.2I296 D297 S301 D302 F305 P306 W330 K334 P335 K338 W339I296-Y299 HydrophobicContact CD1-CD2 4.37Å; I296-Y299 HydrophobicContact CD1-CE2 4.14Å; I296-Y299 WeakPolarHBondContact O-CB 3.41Å; I296-Y299 WeakPolarHBondContact O-CD2 3.26Å; I296-Y299 PolarHBondContact O-N 2.92Å; D297-Y299 PolarHBondContact O-N 2.57Å; D297-Y299 VanDerWaalsContact O-N 3.13Å; Y299-S301 VanDerWaalsContact C-N 3.27Å; Y299-D302 PolarHBondContact O-N 2.99Å; Y299-F305 HydrophobicContact CE1-CB 3.97Å; Y299-P306 HydrophobicContact CD2-CG 4.1Å; Y299-P306 HydrophobicContact CE2-CG 3.88Å; Y299-P306 VanDerWaalsContact CZ-CD 3.44Å; Y299-W330 HydrophobicContact CE2-CH2 4.34Å; Y299-W330 HydrophobicContact CE2-CZ2 4.25Å; Y299-W330 WeakPolarHBondContact OH-CZ2 3.4Å; Y299-K334 HydrophobicContact CD2-CG 4.48Å; Y299-K334 HydrophobicContact CE2-CB 4.49Å; Y299-K334 HydrophobicContact CE2-CD 4.45Å; Y299-K334 HydrophobicContact CE2-CG 3.75Å; Y299-P335 HydrophobicContact CD2-CG 4.31Å; Y299-P335 HydrophobicContact CG-CG 4.36Å; Y299-K338 HydrophobicContact CD1-CB 3.66Å; Y299-K338 HydrophobicContact CD1-CD 3.84Å; Y299-K338 HydrophobicContact CD1-CG 3.83Å; Y299-K338 HydrophobicContact CE1-CB 3.65Å; Y299-K338 HydrophobicContact CE1-CG 4.35Å; Y299-K338 HydrophobicContact CG-CB 4.2Å; Y299-K338 HydrophobicContact CG-CD 4.43Å; Y299-K338 HydrophobicContact CG-CG 4.15Å; Y299-K338 PolarHBondContact O-NZ 2.69Å; Y299-W339 PolarHBondContact OH-O 2.88Å
300N96.2Very high96.5Very high101 Ų10130.5 Ų30.554%0.5416%0.161SC..G310 helixtrans-74.6-19.2173.9-57.8-40000112.3D297 Y298 D302D297-N300 WeakPolarHBondContact O-CB 3.44Å; D297-N300 PolarHBondContact O-N 2.93Å; D297-N300 PolarHBondContact O-ND2 2.9Å; Y298-N300 PolarHBondContact O-N 2.87Å; N300-D302 VanDerWaalsContact C-N 3.26Å
301S97.8Very high96.6Very high1 Ų129.5 Ų29.51%0.00716%0.155CC..G310 helixtrans-85.88.8170.8-52.80000113.1Y261 T268 Y298 Y299 V303Y261-S301 VanDerWaalsContact CA-OG 3.32Å; Y261-S301 WeakPolarHBondContact CA-OG 3.45Å; Y261-S301 WeakPolarHBondContact CB-OG 3.22Å; Y261-S301 WeakPolarHBondContact O-CB 3.36Å; Y261-S301 PolarHBondContact O-OG 3.37Å; T268-S301 WeakPolarHBondContact CB-O 3.43Å; T268-S301 VanDerWaalsContact CG2-O 3.3Å; T268-S301 WeakPolarHBondContact CG2-O 3.48Å; T268-S301 PolarHBondContact OG1-O 2.78Å; Y298-S301 WeakPolarHBondContact O-CA 3.47Å; Y298-S301 WeakPolarHBondContact O-CB 3.41Å; Y298-S301 PolarHBondContact O-N 2.95Å; Y299-S301 VanDerWaalsContact C-N 3.27Å; S301-V303 PolarHBondContact O-N 3.17Å
302D96.1Very high96.6Very high61 Ų6127.7 Ų27.733%0.32615%0.145SC..THydrogen-bonded Turntrans57.925179.1-72.3-30.4000115.9R272 Y299 N300 K338R272-D302 IonicContact CZ-OD2 3.82Å; R272-D302 VanDerWaalsContact NH2-CG 3.34Å; R272-D302 IonicContact NH2-OD2 2.84Å; R272-D302 PolarHBondContact NH2-OD2 3.05Å; Y299-D302 PolarHBondContact O-N 2.99Å; N300-D302 VanDerWaalsContact C-N 3.26Å; D302-K338 IonicContact OD1-NZ 2.7Å; D302-K338 PolarHBondContact OD1-NZ 2.93Å
303V98.2Very high96.4Very high5 Ų528.2 Ų28.23%0.0316%0.162CC..  trans-61.8153.1167.1-56.90000109.7V264 T268 S284 T286 Y298 S301 F305V264-V303 HydrophobicContact CG1-CG1 3.47Å; V264-V303 VanDerWaalsContact CG1-CG1 3.47Å; T268-V303 HydrophobicContact CG2-CB 4.45Å; T268-V303 HydrophobicContact CG2-CG1 3.82Å; S284-V303 WeakPolarHBondContact OG-CA 3.31Å; T286-V303 HydrophobicContact CG2-CG1 3.84Å; Y298-V303 WeakPolarHBondContact O-CG2 3.49Å; S301-V303 PolarHBondContact O-N 3.17Å; V303-F305 VanDerWaalsContact C-N 3.3Å; V303-F305 PolarHBondContact O-N 3.04Å
304T97.5Very high96.4Very high20 Ų2023.2 Ų23.212%0.12314%0.138CC..SBendtrans-58.1-48.6174-53.20000110.2W17 F283 S284W17-T304 HydrophobicContact CD2-CG2 3.75Å; W17-T304 HydrophobicContact CG-CG2 3.88Å; W17-T304 HydrophobicContact CZ2-CG2 3.88Å; W17-T304 VanDerWaalsContact NE1-CG2 3.28Å; F283-T304 HydrophobicContact CD2-CG2 3.68Å; F283-T304 HydrophobicContact CE2-CG2 3.63Å; S284-T304 PolarHBondContact N-OG1 3.44Å; S284-T304 WeakPolarHBondContact O-CA 3.42Å; S284-T304 WeakPolarHBondContact O-CB 3.42Å; S284-T304 PolarHBondContact O-N 3.09Å; S284-T304 PolarHBondContact O-OG1 2.65Å; S284-T304 PolarHBondContact OG-N 3.08Å
305F97.9Very high96.3Very high0 Ų025.8 Ų25.80%015%0.148CC..EExtended strand (participates in β ladder)trans-163.5150.716349.1-106.5000111.1I22 F283 S284 M285 Y299 V303 L307 W339 N341 T375 I377I22-F305 HydrophobicContact CD1-CZ 4.18Å; F283-F305 HydrophobicContact CE2-CD1 4.26Å; F283-F305 AromaticContact CE2-CE1 3.54Å; F283-F305 HydrophobicContact CE2-CE1 3.54Å; F283-F305 HydrophobicContact CE2-CE2 4.32Å; F283-F305 AromaticContact CE2-CZ 3.58Å; F283-F305 HydrophobicContact CE2-CZ 3.58Å; F283-F305 AromaticContact CZ-CE1 3.87Å; F283-F305 HydrophobicContact CZ-CE1 3.87Å; F283-F305 AromaticContact CZ-CE2 3.81Å; F283-F305 HydrophobicContact CZ-CE2 3.81Å; F283-F305 AromaticContact CZ-CZ 3.39Å; F283-F305 HydrophobicContact CZ-CZ 3.39Å; S284-F305 PolarHBondContact O-N 3.19Å; M285-F305 WeakPolarHBondContact CA-O 3.45Å; M285-F305 HydrophobicContact CB-CD2 4.03Å; M285-F305 HydrophobicContact CB-CE2 3.92Å; M285-F305 VanDerWaalsContact CB-O 3.27Å; M285-F305 WeakPolarHBondContact CB-O 3.18Å; M285-F305 HydrophobicContact SD-CE2 3.98Å; Y299-F305 HydrophobicContact CE1-CB 3.97Å; V303-F305 VanDerWaalsContact C-N 3.3Å; V303-F305 PolarHBondContact O-N 3.04Å; F305-L307 HydrophobicContact CE2-CD2 4.36Å; F305-W339 WeakPolarHBondContact CB-O 3.36Å; F305-W339 AromaticContact CD1-CD1 3.93Å; F305-N341 HydrophobicContact CD1-CB 4.15Å; F305-N341 HydrophobicContact CD2-CB 3.57Å; F305-N341 WeakPolarHBondContact CD2-ND2 3.45Å; F305-N341 HydrophobicContact CE1-CB 4.09Å; F305-N341 HydrophobicContact CE2-CB 3.51Å; F305-N341 HydrophobicContact CG-CB 3.9Å; F305-N341 WeakPolarHBondContact CG-ND2 3.38Å; F305-N341 HydrophobicContact CZ-CB 3.77Å; F305-T375 HydrophobicContact CE1-CG2 4.18Å; F305-T375 HydrophobicContact CZ-CG2 4.02Å; F305-I377 HydrophobicContact CE2-CD1 4.24Å; F305-I377 HydrophobicContact CZ-CD1 4.1Å
306P98.1Very high96Very high2 Ų227.9 Ų27.91%0.01317%0.167CC..EExtended strand (participates in β ladder)trans-79140.5164.332.3-29.5000110T286 V295 Y298 Y299 N308 W330 N341T286-P306 WeakPolarHBondContact OG1-CA 3.05Å; T286-P306 WeakPolarHBondContact OG1-CB 3.28Å; V295-P306 HydrophobicContact CG1-CB 3.92Å; V295-P306 HydrophobicContact CG1-CG 3.91Å; V295-P306 WeakPolarHBondContact O-CB 3.43Å; V295-P306 WeakPolarHBondContact O-CG 3.35Å; Y298-P306 HydrophobicContact CD2-CB 4.37Å; Y298-P306 HydrophobicContact CG-CB 4.39Å; Y299-P306 HydrophobicContact CD2-CG 4.1Å; Y299-P306 HydrophobicContact CE2-CG 3.88Å; Y299-P306 VanDerWaalsContact CZ-CD 3.44Å; P306-N308 PolarHBondContact O-N 3.17Å; P306-W330 HydrophobicContact CG-CH2 4.32Å; P306-N341 PolarHBondContact O-ND2 2.63Å
307L97.9Very high95.8Very high2 Ų233.4 Ų33.41%0.0119%0.192CC..  trans-61.7128.3-178.8-78.4169.8000111.2W60 R212 M285 T286 E287 F305 F309 V343 I377W60-L307 HydrophobicContact CH2-CD1 4.27Å; W60-L307 HydrophobicContact CZ3-CD1 4.42Å; R212-L307 HydrophobicContact CG-CD1 4.29Å; M285-L307 HydrophobicContact CG-CG 4.4Å; M285-L307 HydrophobicContact SD-CD1 4.28Å; M285-L307 HydrophobicContact SD-CD2 3.76Å; M285-L307 HydrophobicContact SD-CG 4.07Å; T286-L307 WeakPolarHBondContact O-CB 3.49Å; T286-L307 PolarHBondContact O-N 2.98Å; E287-L307 HydrophobicContact CB-CD1 4.09Å; E287-L307 HydrophobicContact CG-CD1 4.34Å; F305-L307 HydrophobicContact CE2-CD2 4.36Å; L307-F309 HydrophobicContact CB-CD1 4.46Å; L307-F309 HydrophobicContact CB-CE1 3.98Å; L307-F309 HydrophobicContact CB-CE2 4.47Å; L307-F309 HydrophobicContact CB-CZ 4Å; L307-F309 HydrophobicContact CD1-CE1 4.14Å; L307-F309 HydrophobicContact CD1-CZ 3.96Å; L307-F309 PolarHBondContact O-N 3.49Å; L307-V343 HydrophobicContact CD2-CG2 3.65Å; L307-I377 HydrophobicContact CD2-CD1 4.42Å; L307-I377 HydrophobicContact CD2-CG1 3.89Å
308N96.9Very high95.6Very high5 Ų531.5 Ų31.53%0.02718%0.183CC..  trans-92.198.5177.4179.69000110.5P306 S310 W330 N341 W342P306-N308 PolarHBondContact O-N 3.17Å; N308-S310 VanDerWaalsContact C-N 3.32Å; N308-S310 VanDerWaalsContact CG-OG 3.3Å; N308-S310 PolarHBondContact ND2-OG 3.3Å; N308-S310 PolarHBondContact O-N 2.65Å; N308-S310 WeakPolarHBondContact OD1-CB 3.37Å; N308-S310 PolarHBondContact OD1-N 2.97Å; N308-S310 VanDerWaalsContact OD1-N 3.09Å; N308-S310 PolarHBondContact OD1-OG 3.41Å; N308-W330 HydrophobicContact CB-CD2 4.12Å; N308-W330 HydrophobicContact CB-CE3 3.8Å; N308-W330 HydrophobicContact CB-CH2 3.65Å; N308-W330 HydrophobicContact CB-CZ2 3.95Å; N308-W330 HydrophobicContact CB-CZ3 3.57Å; N308-W330 VanDerWaalsContact ND2-CD2 3.28Å; N308-N341 PolarHBondContact N-OD1 2.94Å; N308-W342 WeakPolarHBondContact ND2-CZ3 3.26Å
309F95.3Very high95.5Very high30 Ų3038.3 Ų38.313%0.13221%0.213CC..G310 helixtrans-86.46.4178.1-63.7-42.4000115.3E287 Y289 L307 L311 V312 V343E287-F309 HydrophobicContact CG-CE2 3.51Å; E287-F309 HydrophobicContact CG-CZ 3.45Å; E287-F309 VanDerWaalsContact CG-CZ 3.45Å; Y289-F309 AromaticContact CD1-CD2 3.79Å; Y289-F309 HydrophobicContact CD1-CD2 3.79Å; Y289-F309 HydrophobicContact CD1-CE2 4.26Å; Y289-F309 HydrophobicContact CD1-CG 4.45Å; Y289-F309 HydrophobicContact CD2-CD2 4.37Å; Y289-F309 HydrophobicContact CD2-CE2 4.06Å; Y289-F309 HydrophobicContact CE1-CB 4.36Å; Y289-F309 AromaticContact CE1-CD2 3.7Å; Y289-F309 HydrophobicContact CE1-CD2 3.7Å; Y289-F309 HydrophobicContact CE1-CE2 4.02Å; Y289-F309 HydrophobicContact CE1-CG 4.07Å; Y289-F309 HydrophobicContact CE2-CD2 4.29Å; Y289-F309 AromaticContact CE2-CE2 3.81Å; Y289-F309 HydrophobicContact CE2-CE2 3.81Å; Y289-F309 HydrophobicContact CE2-CZ 4.35Å; Y289-F309 HydrophobicContact CG-CD2 4.15Å; Y289-F309 HydrophobicContact CG-CE2 4.28Å; Y289-F309 AromaticContact CZ-CD2 3.97Å; Y289-F309 AromaticContact CZ-CE2 3.79Å; L307-F309 HydrophobicContact CB-CD1 4.46Å; L307-F309 HydrophobicContact CB-CE1 3.98Å; L307-F309 HydrophobicContact CB-CE2 4.47Å; L307-F309 HydrophobicContact CB-CZ 4Å; L307-F309 HydrophobicContact CD1-CE1 4.14Å; L307-F309 HydrophobicContact CD1-CZ 3.96Å; L307-F309 PolarHBondContact O-N 3.49Å; F309-L311 PolarHBondContact O-N 2.86Å; F309-L311 VanDerWaalsContact O-N 3.12Å; F309-V312 HydrophobicContact CB-CB 4.31Å; F309-V312 HydrophobicContact CB-CG2 4.08Å; F309-V312 HydrophobicContact CD1-CG2 3.69Å; F309-V312 HydrophobicContact CG-CG2 4.29Å; F309-V312 WeakPolarHBondContact O-CB 3.3Å; F309-V312 PolarHBondContact O-N 2.81Å; F309-V343 HydrophobicContact CD1-CB 4.17Å; F309-V343 HydrophobicContact CD1-CG1 4.22Å; F309-V343 HydrophobicContact CD1-CG2 4.27Å; F309-V343 HydrophobicContact CE1-CG1 4.23Å; F309-V343 HydrophobicContact CE1-CG2 4.37Å
310S93.8Very high95.4Very high37 Ų3738.7 Ų38.726%0.25922%0.215SC..G310 helixtrans-53.6-37.4-179.458.10000113.6N308 L326N308-S310 VanDerWaalsContact C-N 3.32Å; N308-S310 VanDerWaalsContact CG-OG 3.3Å; N308-S310 PolarHBondContact ND2-OG 3.3Å; N308-S310 PolarHBondContact O-N 2.65Å; N308-S310 WeakPolarHBondContact OD1-CB 3.37Å; N308-S310 PolarHBondContact OD1-N 2.97Å; N308-S310 VanDerWaalsContact OD1-N 3.09Å; N308-S310 PolarHBondContact OD1-OG 3.41Å; S310-L326 WeakPolarHBondContact O-CD1 3.32Å
311L96.1Very high95.3Very high1 Ų136.9 Ų36.91%0.00521%0.211CC..G310 helixtrans-86.6-8.2178.8-62.2-177.7000114F309 G313 W314 L323 L326 W342 V343 V344 L368 L372F309-L311 PolarHBondContact O-N 2.86Å; F309-L311 VanDerWaalsContact O-N 3.12Å; L311-G313 VanDerWaalsContact C-N 3.27Å; L311-G313 PolarHBondContact O-N 2.8Å; L311-W314 WeakPolarHBondContact O-CB 3.49Å; L311-W314 PolarHBondContact O-N 2.95Å; L311-W314 VanDerWaalsContact O-N 3.15Å; L311-L323 HydrophobicContact CD2-CD2 3.97Å; L311-L326 HydrophobicContact CD2-CB 4.34Å; L311-L326 HydrophobicContact CD2-CD1 4.02Å; L311-W342 HydrophobicContact CD1-CD2 4.44Å; L311-W342 HydrophobicContact CD1-CE3 3.61Å; L311-W342 HydrophobicContact CD1-CZ3 4.26Å; L311-W342 HydrophobicContact CG-CE3 4.18Å; L311-V343 CarbonylContact C-O 3.53Å; L311-V343 WeakPolarHBondContact CB-O 3.41Å; L311-V344 HydrophobicContact CB-CG1 4.13Å; L311-V344 HydrophobicContact CD1-CG1 4.38Å; L311-L368 HydrophobicContact CD1-CD2 4.38Å; L311-L372 HydrophobicContact CD1-CD1 4.2Å
312V94.5Very high95.3Very high5 Ų540.9 Ų40.93%0.0323%0.229CC..THydrogen-bonded Turntrans-68.2-30.6176.9176.80000111.2F309 W314 V343 Q349 R355F309-V312 HydrophobicContact CB-CB 4.31Å; F309-V312 HydrophobicContact CB-CG2 4.08Å; F309-V312 HydrophobicContact CD1-CG2 3.69Å; F309-V312 HydrophobicContact CG-CG2 4.29Å; F309-V312 WeakPolarHBondContact O-CB 3.3Å; F309-V312 PolarHBondContact O-N 2.81Å; V312-W314 PolarHBondContact O-N 2.77Å; V312-V343 HydrophobicContact CG2-CB 3.99Å; V312-V343 HydrophobicContact CG2-CG1 3.83Å; V312-V343 WeakPolarHBondContact CG2-O 3.44Å; V312-V343 PolarHBondContact N-O 3.26Å; V312-Q349 HydrophobicContact CG1-CB 3.85Å; V312-Q349 HydrophobicContact CG1-CG 3.59Å; V312-R355 PolarHBondContact O-NE 2.89Å; V312-R355 PolarHBondContact O-NH1 2.94Å
313G90.2Very high95.3Very high56 Ų5638 Ų3858%0.57721%0.214SC*.THydrogen-bonded Turntrans-751.6173.200000115.1L311 K315L311-G313 VanDerWaalsContact C-N 3.27Å; L311-G313 PolarHBondContact O-N 2.8Å; G313-K315 PolarHBondContact O-N 3.4Å
314W94.6Very high95.3Very high9 Ų939.9 Ų39.93%0.03422%0.223CC..  trans-66.6122.1-178.1-178.716000111.6L311 V312 L323 I352 R355 L356 V364 A365 L368 L516L311-W314 WeakPolarHBondContact O-CB 3.49Å; L311-W314 PolarHBondContact O-N 2.95Å; L311-W314 VanDerWaalsContact O-N 3.15Å; V312-W314 PolarHBondContact O-N 2.77Å; W314-L323 HydrophobicContact CB-CD2 4.3Å; W314-L323 HydrophobicContact CD2-CD1 4.26Å; W314-L323 HydrophobicContact CD2-CD2 3.97Å; W314-L323 HydrophobicContact CG-CD2 3.8Å; W314-L323 HydrophobicContact CH2-CD1 4.48Å; W314-L323 HydrophobicContact CZ2-CD1 3.83Å; W314-I352 HydrophobicContact CB-CD1 4.44Å; W314-I352 HydrophobicContact CD2-CD1 4.47Å; W314-I352 HydrophobicContact CE3-CD1 4.22Å; W314-R355 WeakPolarHBondContact O-CB 3.41Å; W314-R355 WeakPolarHBondContact O-CD 3.45Å; W314-R355 PolarHBondContact O-NE 3.42Å; W314-L356 HydrophobicContact CD2-CD2 4.06Å; W314-L356 HydrophobicContact CG-CD2 4.02Å; W314-L356 HydrophobicContact CH2-CD1 4.43Å; W314-L356 HydrophobicContact CZ2-CD1 4.19Å; W314-L356 HydrophobicContact CZ2-CD2 4.38Å; W314-V364 HydrophobicContact CH2-CG1 4.25Å; W314-A365 HydrophobicContact CH2-CB 4.19Å; W314-A365 HydrophobicContact CZ3-CB 3.88Å; W314-L368 HydrophobicContact CE3-CD2 4.31Å; W314-L368 HydrophobicContact CH2-CD2 3.94Å; W314-L368 HydrophobicContact CZ3-CB 4.44Å; W314-L368 HydrophobicContact CZ3-CD2 3.64Å; W314-L516 HydrophobicContact CH2-CD2 4.49Å; W314-L516 HydrophobicContact CZ2-CD2 3.66Å; W314-L516 HydrophobicContact CZ2-CG 4.39Å
315K93.8Very high95.3Very high108 Ų10845.1 Ų45.147%0.4724%0.244SC..  trans-131.1171.3179.859.5-176.3-174.7179.80111.9G313 E317 T318 R355G313-K315 PolarHBondContact O-N 3.4Å; K315-E317 WeakPolarHBondContact CD-OE2 3.09Å; K315-E317 VanDerWaalsContact CG-OE2 3.24Å; K315-E317 WeakPolarHBondContact CG-OE2 3.35Å; K315-E317 PolarHBondContact O-N 3.34Å; K315-E317 VanDerWaalsContact O-N 3.16Å; K315-T318 WeakPolarHBondContact CG-OG1 3.48Å; K315-T318 PolarHBondContact N-OG1 2.93Å; K315-T318 VanDerWaalsContact N-OG1 3.16Å; K315-T318 VanDerWaalsContact O-CB 3.31Å; K315-T318 WeakPolarHBondContact O-CB 3.39Å; K315-T318 PolarHBondContact O-N 3.19Å; K315-T318 PolarHBondContact O-OG1 3Å; K315-R355 WeakPolarHBondContact CA-O 3.14Å; K315-R355 HydrophobicContact CB-CB 4.49Å
316A91.6Very high95.2Very high58 Ų5847.9 Ų47.948%0.47926%0.259SS..THydrogen-bonded Turntrans-56.6-30.7-176.900000113.7R355A316-R355 PolarHBondContact N-O 3.06Å
317E91.8Very high95.1Very high133 Ų13347.8 Ų47.862%0.62126%0.258SS*.THydrogen-bonded Turntrans-83.9-10.1-179.4-52.874.5-157.400113.6K315 K319K315-E317 WeakPolarHBondContact CD-OE2 3.09Å; K315-E317 VanDerWaalsContact CG-OE2 3.24Å; K315-E317 WeakPolarHBondContact CG-OE2 3.35Å; K315-E317 PolarHBondContact O-N 3.34Å; K315-E317 VanDerWaalsContact O-N 3.16Å; E317-K319 PolarHBondContact O-N 2.84Å
318T94.5Very high95Very high26 Ų2650 Ų5016%0.1627%0.272CS..  trans-65.5122.7-180-55.90000110K315 E322 L323K315-T318 WeakPolarHBondContact CG-OG1 3.48Å; K315-T318 PolarHBondContact N-OG1 2.93Å; K315-T318 VanDerWaalsContact N-OG1 3.16Å; K315-T318 VanDerWaalsContact O-CB 3.31Å; K315-T318 WeakPolarHBondContact O-CB 3.39Å; K315-T318 PolarHBondContact O-N 3.19Å; K315-T318 PolarHBondContact O-OG1 3Å; T318-E322 HydrophobicContact CG2-CB 3.97Å; T318-L323 HydrophobicContact CG2-CD2 3.77Å; T318-L323 HydrophobicContact CG2-CG 3.94Å
319K94.5Very high95Very high144 Ų14453.4 Ų53.463%0.62629%0.29SS*.  trans-72.7148.5177.4-60.1175.9-179.3-179.90110.4E317 S321 E322 L323E317-K319 PolarHBondContact O-N 2.84Å; K319-S321 PolarHBondContact O-N 2.89Å; K319-S321 VanDerWaalsContact O-N 3.16Å; K319-E322 HydrophobicContact CB-CG 4.23Å; K319-E322 VanDerWaalsContact CB-OE2 3.29Å; K319-E322 WeakPolarHBondContact CB-OE2 3.22Å; K319-E322 WeakPolarHBondContact CG-OE2 3Å; K319-E322 PolarHBondContact N-OE2 2.88Å; K319-E322 WeakPolarHBondContact O-CB 3.41Å; K319-E322 PolarHBondContact O-N 3.4Å; K319-L323 PolarHBondContact O-N 3.42Å
320T95.5Very high95.1Very high9 Ų952 Ų526%0.05528%0.284CS..Hα-helixtrans-53.5-38.2173.4-570000112.7E322 L323 I324 E495 V497 L498T320-E322 PolarHBondContact O-N 2.79Å; T320-L323 PolarHBondContact O-N 3.41Å; T320-I324 HydrophobicContact CG2-CD1 3.91Å; T320-I324 HydrophobicContact CG2-CG1 4.37Å; T320-I324 WeakPolarHBondContact O-CG1 3.43Å; T320-I324 PolarHBondContact O-N 3.09Å; T320-E495 WeakPolarHBondContact CB-O 3.27Å; T320-E495 PolarHBondContact OG1-O 2.8Å; T320-V497 WeakPolarHBondContact CG2-O 3.19Å; T320-L498 HydrophobicContact CG2-CB 3.62Å; T320-L498 HydrophobicContact CG2-CD1 4.33Å; T320-L498 HydrophobicContact CG2-CG 4.06Å
321S95.8Very high95.1Very high63 Ų6351.9 Ų51.944%0.44128%0.279SS..Hα-helixtrans-61.8-30.4177590000113.2K319 K325K319-S321 PolarHBondContact O-N 2.89Å; K319-S321 VanDerWaalsContact O-N 3.16Å; S321-K325 VanDerWaalsContact O-CG 3.28Å; S321-K325 WeakPolarHBondContact O-CG 3.48Å; S321-K325 PolarHBondContact O-N 3.15Å; S321-K325 VanDerWaalsContact O-N 3.12Å
322E96.7Very high95.1Very high85 Ų8558.1 Ų58.140%0.39731%0.312SS..Hα-helixtrans-72.4-45.4176.1-64.6172.39100109.9T318 K319 T320 I324 K325 L326T318-E322 HydrophobicContact CG2-CB 3.97Å; K319-E322 HydrophobicContact CB-CG 4.23Å; K319-E322 VanDerWaalsContact CB-OE2 3.29Å; K319-E322 WeakPolarHBondContact CB-OE2 3.22Å; K319-E322 WeakPolarHBondContact CG-OE2 3Å; K319-E322 PolarHBondContact N-OE2 2.88Å; K319-E322 WeakPolarHBondContact O-CB 3.41Å; K319-E322 PolarHBondContact O-N 3.4Å; T320-E322 PolarHBondContact O-N 2.79Å; E322-I324 VanDerWaalsContact C-N 3.32Å; E322-I324 PolarHBondContact O-N 2.96Å; E322-K325 WeakPolarHBondContact O-CB 3.36Å; E322-K325 PolarHBondContact O-N 3.37Å; E322-K325 VanDerWaalsContact O-N 3.08Å; E322-L326 WeakPolarHBondContact O-CG 3.48Å; E322-L326 PolarHBondContact O-N 2.66Å
323L97.1Very high95.2Very high0 Ų062 Ų620%033%0.328CS..Hα-helixtrans-58.1-43.6174.4-61.5177.2000112.3L311 W314 T318 K319 T320 K325 L326 I327 L498 L516L311-L323 HydrophobicContact CD2-CD2 3.97Å; W314-L323 HydrophobicContact CB-CD2 4.3Å; W314-L323 HydrophobicContact CD2-CD1 4.26Å; W314-L323 HydrophobicContact CD2-CD2 3.97Å; W314-L323 HydrophobicContact CG-CD2 3.8Å; W314-L323 HydrophobicContact CH2-CD1 4.48Å; W314-L323 HydrophobicContact CZ2-CD1 3.83Å; T318-L323 HydrophobicContact CG2-CD2 3.77Å; T318-L323 HydrophobicContact CG2-CG 3.94Å; K319-L323 PolarHBondContact O-N 3.42Å; T320-L323 PolarHBondContact O-N 3.41Å; L323-K325 VanDerWaalsContact C-N 3.33Å; L323-K325 PolarHBondContact O-N 2.74Å; L323-L326 HydrophobicContact CD2-CD1 4.46Å; L323-L326 PolarHBondContact O-N 3.14Å; L323-I327 WeakPolarHBondContact O-CD1 3.45Å; L323-I327 VanDerWaalsContact O-CG1 3.3Å; L323-I327 WeakPolarHBondContact O-CG1 3.34Å; L323-I327 PolarHBondContact O-N 2.85Å; L323-L498 HydrophobicContact CB-CD1 3.89Å; L323-L498 HydrophobicContact CD1-CD1 4.27Å; L323-L516 HydrophobicContact CD1-CD2 3.31Å
324I96.8Very high95.4Very high44 Ų4459.7 Ų59.723%0.22630%0.303CS..Hα-helixtrans-58.3-46.5174.9-71.2168.2000110.3T320 E322 L326 I327 T328 I489 L498T320-I324 HydrophobicContact CG2-CD1 3.91Å; T320-I324 HydrophobicContact CG2-CG1 4.37Å; T320-I324 WeakPolarHBondContact O-CG1 3.43Å; T320-I324 PolarHBondContact O-N 3.09Å; E322-I324 VanDerWaalsContact C-N 3.32Å; E322-I324 PolarHBondContact O-N 2.96Å; I324-L326 PolarHBondContact O-N 2.81Å; I324-I327 PolarHBondContact O-N 2.91Å; I324-T328 WeakPolarHBondContact O-CB 3.33Å; I324-T328 PolarHBondContact O-N 3.05Å; I324-T328 PolarHBondContact O-OG1 2.7Å; I324-T328 VanDerWaalsContact O-OG1 3.07Å; I324-I489 HydrophobicContact CD1-CG2 4.08Å; I324-I489 HydrophobicContact CG1-CG2 4.2Å; I324-I489 HydrophobicContact CG2-CG1 4.25Å; I324-I489 HydrophobicContact CG2-CG2 3.95Å; I324-L498 HydrophobicContact CG1-CD1 4.3Å; I324-L498 HydrophobicContact CG1-CG 4.06Å
325K97Very high95.4Very high131 Ų13161.2 Ų61.257%0.5731%0.314SS*.Hα-helixtrans-60.5-42.8177-74.9172.1-178.2-177.70112.1S321 E322 L323 I327 T328 N329S321-K325 VanDerWaalsContact O-CG 3.28Å; S321-K325 WeakPolarHBondContact O-CG 3.48Å; S321-K325 PolarHBondContact O-N 3.15Å; S321-K325 VanDerWaalsContact O-N 3.12Å; E322-K325 WeakPolarHBondContact O-CB 3.36Å; E322-K325 PolarHBondContact O-N 3.37Å; E322-K325 VanDerWaalsContact O-N 3.08Å; L323-K325 VanDerWaalsContact C-N 3.33Å; L323-K325 PolarHBondContact O-N 2.74Å; K325-I327 VanDerWaalsContact C-N 3.34Å; K325-I327 PolarHBondContact O-N 3.17Å; K325-T328 PolarHBondContact O-N 2.78Å; K325-N329 WeakPolarHBondContact O-CB 3.42Å; K325-N329 PolarHBondContact O-N 3.46Å; K325-N329 PolarHBondContact O-ND2 3.46Å; K325-N329 PolarHBondContact O-OD1 2.96Å
326L96.9Very high95.3Very high57 Ų5765.5 Ų65.530%0.29834%0.335SS..Hα-helixtrans-60.2-45.8177.3-63.2175.9000111.1S310 L311 E322 L323 I324 W330S310-L326 WeakPolarHBondContact O-CD1 3.32Å; L311-L326 HydrophobicContact CD2-CB 4.34Å; L311-L326 HydrophobicContact CD2-CD1 4.02Å; E322-L326 WeakPolarHBondContact O-CG 3.48Å; E322-L326 PolarHBondContact O-N 2.66Å; L323-L326 HydrophobicContact CD2-CD1 4.46Å; L323-L326 PolarHBondContact O-N 3.14Å; I324-L326 PolarHBondContact O-N 2.81Å; L326-W330 PolarHBondContact O-N 2.92Å; L326-W330 VanDerWaalsContact O-N 3.14Å
327I96.8Very high95.2Very high0 Ų065.7 Ų65.70%034%0.343CS..Hα-helixtrans-64.5-49.1179.3-65.1158.2000111L323 I324 K325 W330 Q331 W342 L368 L372 I489 L498L323-I327 WeakPolarHBondContact O-CD1 3.45Å; L323-I327 VanDerWaalsContact O-CG1 3.3Å; L323-I327 WeakPolarHBondContact O-CG1 3.34Å; L323-I327 PolarHBondContact O-N 2.85Å; I324-I327 PolarHBondContact O-N 2.91Å; K325-I327 VanDerWaalsContact C-N 3.34Å; K325-I327 PolarHBondContact O-N 3.17Å; I327-W330 PolarHBondContact O-N 3.49Å; I327-Q331 WeakPolarHBondContact O-CG 3.28Å; I327-Q331 PolarHBondContact O-N 3.23Å; I327-Q331 VanDerWaalsContact O-N 3.17Å; I327-W342 HydrophobicContact CB-CH2 4.11Å; I327-W342 HydrophobicContact CB-CZ3 4.44Å; I327-W342 HydrophobicContact CG1-CH2 4.11Å; I327-W342 HydrophobicContact CG1-CZ3 4.01Å; I327-W342 HydrophobicContact CG2-CH2 3.95Å; I327-W342 HydrophobicContact CG2-CZ2 4.38Å; I327-L368 HydrophobicContact CD1-CD1 3.95Å; I327-L372 HydrophobicContact CD1-CD1 4.17Å; I327-L372 HydrophobicContact CD1-CD2 4.14Å; I327-L372 HydrophobicContact CG1-CD1 4.1Å; I327-L372 HydrophobicContact CG1-CD2 4.29Å; I327-L372 HydrophobicContact CG2-CD2 3.82Å; I327-I489 HydrophobicContact CG2-CD1 4.44Å; I327-L498 HydrophobicContact CD1-CD1 4.25Å
328T96Very high95.4Very high50 Ų5062.3 Ų62.331%0.30733%0.326SS..Hα-helixtrans-65.9-42.6-178.8-61.40000111.7I324 K325 W330 Q331 L332I324-T328 WeakPolarHBondContact O-CB 3.33Å; I324-T328 PolarHBondContact O-N 3.05Å; I324-T328 PolarHBondContact O-OG1 2.7Å; I324-T328 VanDerWaalsContact O-OG1 3.07Å; K325-T328 PolarHBondContact O-N 2.78Å; T328-W330 VanDerWaalsContact C-N 3.35Å; T328-W330 PolarHBondContact O-N 3.15Å; T328-Q331 PolarHBondContact O-N 3.46Å; T328-L332 HydrophobicContact CG2-CD1 3.69Å; T328-L332 HydrophobicContact CG2-CG 4.14Å; T328-L332 WeakPolarHBondContact O-CB 3.06Å; T328-L332 VanDerWaalsContact O-CG 3.26Å; T328-L332 WeakPolarHBondContact O-CG 3.07Å; T328-L332 PolarHBondContact O-N 3.47Å
329N96.2Very high95.4Very high76 Ų7662.2 Ų62.241%0.40632%0.323SS..Hα-helixtrans-62.8-42179.2-74.3-8.3000111.8L292 K325 L332 K333L292-N329 HydrophobicContact CD2-CB 4.08Å; K325-N329 WeakPolarHBondContact O-CB 3.42Å; K325-N329 PolarHBondContact O-N 3.46Å; K325-N329 PolarHBondContact O-ND2 3.46Å; K325-N329 PolarHBondContact O-OD1 2.96Å; N329-L332 PolarHBondContact O-N 3.39Å; N329-K333 WeakPolarHBondContact O-CB 3.48Å; N329-K333 PolarHBondContact O-N 3.33Å
330W96.3Very high95.5Very high1 Ų155.3 Ų55.30%0.00429%0.293CS..Hα-helixtrans-59.1-49.1174.6179-93.7000111.2L292 V295 I296 Y299 P306 N308 L326 I327 T328 L332 K333 K334 S340 W342L292-W330 HydrophobicContact CD1-CE3 3.54Å; L292-W330 HydrophobicContact CD1-CZ3 3.81Å; V295-W330 HydrophobicContact CG1-CH2 4.13Å; V295-W330 HydrophobicContact CG1-CZ3 3.81Å; I296-W330 HydrophobicContact CD1-CE3 4.4Å; I296-W330 HydrophobicContact CD1-CH2 4.48Å; I296-W330 HydrophobicContact CD1-CZ3 4.2Å; Y299-W330 HydrophobicContact CE2-CH2 4.34Å; Y299-W330 HydrophobicContact CE2-CZ2 4.25Å; Y299-W330 WeakPolarHBondContact OH-CZ2 3.4Å; P306-W330 HydrophobicContact CG-CH2 4.32Å; N308-W330 HydrophobicContact CB-CD2 4.12Å; N308-W330 HydrophobicContact CB-CE3 3.8Å; N308-W330 HydrophobicContact CB-CH2 3.65Å; N308-W330 HydrophobicContact CB-CZ2 3.95Å; N308-W330 HydrophobicContact CB-CZ3 3.57Å; N308-W330 VanDerWaalsContact ND2-CD2 3.28Å; L326-W330 PolarHBondContact O-N 2.92Å; L326-W330 VanDerWaalsContact O-N 3.14Å; I327-W330 PolarHBondContact O-N 3.49Å; T328-W330 VanDerWaalsContact C-N 3.35Å; T328-W330 PolarHBondContact O-N 3.15Å; W330-L332 VanDerWaalsContact C-N 3.29Å; W330-L332 PolarHBondContact O-N 3.38Å; W330-K333 PolarHBondContact O-N 3.11Å; W330-K334 WeakPolarHBondContact O-CB 3.23Å; W330-K334 PolarHBondContact O-N 3.18Å; W330-S340 PolarHBondContact NE1-OG 3.08Å; W330-S340 VanDerWaalsContact NE1-OG 3.09Å; W330-W342 HydrophobicContact CB-CH2 3.91Å; W330-W342 HydrophobicContact CB-CZ3 4.36Å; W330-W342 AromaticContact CD1-CH2 3.79Å; W330-W342 AromaticContact CD1-CZ2 3.87Å; W330-W342 AromaticContact CG-CH2 3.99Å; W330-W342 HydrophobicContact CG-CH2 3.99Å; W330-W342 HydrophobicContact CG-CZ2 4.49Å; W330-W342 HydrophobicContact CG-CZ3 4.47Å
331Q95Very high95.6Very high33 Ų3354.9 Ų54.915%0.15429%0.29CS..Hα-helixtrans-65.2-32.1-179.3-67.6-65.8-0.300113.6I327 T328 S484 V487I327-Q331 WeakPolarHBondContact O-CG 3.28Å; I327-Q331 PolarHBondContact O-N 3.23Å; I327-Q331 VanDerWaalsContact O-N 3.17Å; T328-Q331 PolarHBondContact O-N 3.46Å; Q331-S484 PolarHBondContact NE2-O 3.1Å; Q331-S484 VanDerWaalsContact NE2-O 3.12Å; Q331-S484 PolarHBondContact OE1-O 3.14Å; Q331-V487 HydrophobicContact CG-CG1 3.76Å
332L95.1Very high95.7Very high133 Ų13352 Ų5270%0.69627%0.269SS*.Hα-helixtrans-76.7-39.8177.6-72.2173.6000113.1T328 N329 W330T328-L332 HydrophobicContact CG2-CD1 3.69Å; T328-L332 HydrophobicContact CG2-CG 4.14Å; T328-L332 WeakPolarHBondContact O-CB 3.06Å; T328-L332 VanDerWaalsContact O-CG 3.26Å; T328-L332 WeakPolarHBondContact O-CG 3.07Å; T328-L332 PolarHBondContact O-N 3.47Å; N329-L332 PolarHBondContact O-N 3.39Å; W330-L332 VanDerWaalsContact C-N 3.29Å; W330-L332 PolarHBondContact O-N 3.38Å
333K96.1Very high95.7Very high85 Ų8548 Ų4837%0.3725%0.251SS..Hα-helixtrans-84.8-30.4-176.1-74.5-172.2168.6-168.90113.2L292 E293 I296 N329 W330L292-K333 HydrophobicContact CD2-CD 3.63Å; L292-K333 HydrophobicContact CG-CD 3.77Å; E293-K333 IonicContact OE1-NZ 2.71Å; E293-K333 PolarHBondContact OE1-NZ 3.04Å; I296-K333 HydrophobicContact CD1-CB 4.17Å; I296-K333 HydrophobicContact CG1-CB 4.12Å; N329-K333 WeakPolarHBondContact O-CB 3.48Å; N329-K333 PolarHBondContact O-N 3.33Å; W330-K333 PolarHBondContact O-N 3.11Å
334K95Very high95.7Very high9 Ų948 Ų484%0.03925%0.251CS..SBendtrans-57130.9175.9-178.5-174.363.560.20109.9I296 Y299 W330 K338 S340 D485I296-K334 HydrophobicContact CD1-CB 4.2Å; Y299-K334 HydrophobicContact CD2-CG 4.48Å; Y299-K334 HydrophobicContact CE2-CB 4.49Å; Y299-K334 HydrophobicContact CE2-CD 4.45Å; Y299-K334 HydrophobicContact CE2-CG 3.75Å; W330-K334 WeakPolarHBondContact O-CB 3.23Å; W330-K334 PolarHBondContact O-N 3.18Å; K334-K338 HydrophobicContact CD-CB 4.46Å; K334-K338 WeakPolarHBondContact CD-O 3.44Å; K334-K338 VanDerWaalsContact CE-O 3.3Å; K334-K338 WeakPolarHBondContact CE-O 3.32Å; K334-K338 HydrophobicContact CG-CB 4.11Å; K334-K338 PolarHBondContact NZ-O 3.12Å; K334-S340 VanDerWaalsContact CD-OG 3.28Å; K334-S340 WeakPolarHBondContact CD-OG 3.47Å; K334-S340 WeakPolarHBondContact CE-OG 3.22Å; K334-D485 WeakPolarHBondContact CE-OD1 3.29Å; K334-D485 IonicContact NZ-OD1 3.09Å; K334-D485 PolarHBondContact NZ-OD1 3.43Å
335P95.3Very high95.7Very high41 Ų4146 Ų4627%0.26624%0.241SC..PPolyproline II helixtrans-58.4147.3178.1-21.131.1000111.8Y299 G337 K338Y299-P335 HydrophobicContact CD2-CG 4.31Å; Y299-P335 HydrophobicContact CG-CG 4.36Å; P335-G337 PolarHBondContact O-N 2.74Å; P335-K338 HydrophobicContact CB-CB 4.45Å; P335-K338 HydrophobicContact CB-CG 3.77Å; P335-K338 HydrophobicContact CG-CG 4.18Å; P335-K338 WeakPolarHBondContact O-CB 3.36Å; P335-K338 PolarHBondContact O-N 2.98Å; P335-K338 VanDerWaalsContact O-N 3.12Å
336E91.9Very high95.7Very high197 Ų19740 Ų4092%0.92122%0.215SC*.THydrogen-bonded Turntrans-56.7136-179.9-170.3176.1-177.200110.8K338E336-K338 PolarHBondContact O-N 2.97Å; E336-K338 VanDerWaalsContact O-N 3.14Å
337G89.8Confident95.6Very high62 Ų6237.4 Ų37.464%0.63920%0.201SC*.THydrogen-bonded Turntrans75-10.8-178.600000115.9P335P335-G337 PolarHBondContact O-N 2.74Å
338K94.4Very high95.5Very high62 Ų6239.1 Ų39.127%0.2721%0.211SC..PPolyproline II helixtrans-74.7154.6174.3-64.2-70.7-177.7157.20111.5Y299 D302 K334 P335 E336 S484Y299-K338 HydrophobicContact CD1-CB 3.66Å; Y299-K338 HydrophobicContact CD1-CD 3.84Å; Y299-K338 HydrophobicContact CD1-CG 3.83Å; Y299-K338 HydrophobicContact CE1-CB 3.65Å; Y299-K338 HydrophobicContact CE1-CG 4.35Å; Y299-K338 HydrophobicContact CG-CB 4.2Å; Y299-K338 HydrophobicContact CG-CD 4.43Å; Y299-K338 HydrophobicContact CG-CG 4.15Å; Y299-K338 PolarHBondContact O-NZ 2.69Å; D302-K338 IonicContact OD1-NZ 2.7Å; D302-K338 PolarHBondContact OD1-NZ 2.93Å; K334-K338 HydrophobicContact CD-CB 4.46Å; K334-K338 WeakPolarHBondContact CD-O 3.44Å; K334-K338 VanDerWaalsContact CE-O 3.3Å; K334-K338 WeakPolarHBondContact CE-O 3.32Å; K334-K338 HydrophobicContact CG-CB 4.11Å; K334-K338 PolarHBondContact NZ-O 3.12Å; P335-K338 HydrophobicContact CB-CB 4.45Å; P335-K338 HydrophobicContact CB-CG 3.77Å; P335-K338 HydrophobicContact CG-CG 4.18Å; P335-K338 WeakPolarHBondContact O-CB 3.36Å; P335-K338 PolarHBondContact O-N 2.98Å; P335-K338 VanDerWaalsContact O-N 3.12Å; E336-K338 PolarHBondContact O-N 2.97Å; E336-K338 VanDerWaalsContact O-N 3.14Å; K338-S484 PolarHBondContact O-OG 2.62Å
339W95.4Very high95.3Very high24 Ų2440.3 Ų40.39%0.09121%0.213CC..PPolyproline II helixtrans-91.2129.8-170.1-159.2-101.4000112.8K18 Y299 F305 T375 S484K18-W339 HydrophobicContact CB-CH2 3.69Å; K18-W339 HydrophobicContact CB-CZ2 3.47Å; K18-W339 VanDerWaalsContact CB-CZ2 3.47Å; K18-W339 HydrophobicContact CB-CZ3 4.44Å; K18-W339 HydrophobicContact CD-CD2 4.21Å; K18-W339 HydrophobicContact CD-CE3 3.81Å; K18-W339 HydrophobicContact CD-CH2 3.65Å; K18-W339 HydrophobicContact CD-CZ2 4.06Å; K18-W339 HydrophobicContact CD-CZ3 3.51Å; K18-W339 VanDerWaalsContact CE-CE3 3.43Å; K18-W339 HydrophobicContact CG-CD2 3.93Å; K18-W339 HydrophobicContact CG-CE3 4.05Å; K18-W339 HydrophobicContact CG-CH2 3.63Å; K18-W339 HydrophobicContact CG-CZ2 3.49Å; K18-W339 VanDerWaalsContact CG-CZ2 3.49Å; K18-W339 HydrophobicContact CG-CZ3 3.91Å; Y299-W339 PolarHBondContact OH-O 2.88Å; F305-W339 WeakPolarHBondContact CB-O 3.36Å; F305-W339 AromaticContact CD1-CD1 3.93Å; W339-T375 PolarHBondContact NE1-OG1 3.26Å; W339-S484 WeakPolarHBondContact CA-OG 3.37Å
340S96.5Very high95.2Very high0 Ų041.9 Ų41.90%022%0.219CC..PPolyproline II helixtrans-78.7159.7178.1-74.10000112.4W330 K334 P373 G374 T375 S484W330-S340 PolarHBondContact NE1-OG 3.08Å; W330-S340 VanDerWaalsContact NE1-OG 3.09Å; K334-S340 VanDerWaalsContact CD-OG 3.28Å; K334-S340 WeakPolarHBondContact CD-OG 3.47Å; K334-S340 WeakPolarHBondContact CE-OG 3.22Å; S340-P373 WeakPolarHBondContact CB-O 3.1Å; S340-G374 CarbonylContact O-C 3.47Å; S340-G374 VanDerWaalsContact O-CA 3.22Å; S340-G374 WeakPolarHBondContact O-CA 3.38Å; S340-T375 PolarHBondContact O-N 2.6Å; S340-S484 PolarHBondContact N-OG 3.22Å; S340-S484 PolarHBondContact OG-O 3.38Å; S340-S484 PolarHBondContact OG-OG 3.41Å
341N97Very high95.2Very high0 Ų041.9 Ų41.90%022%0.219CC..EExtended strand (participates in β ladder)trans-144.7164.5165.673.193.1000111.3F305 P306 N308 T375F305-N341 HydrophobicContact CD1-CB 4.15Å; F305-N341 HydrophobicContact CD2-CB 3.57Å; F305-N341 WeakPolarHBondContact CD2-ND2 3.45Å; F305-N341 HydrophobicContact CE1-CB 4.09Å; F305-N341 HydrophobicContact CE2-CB 3.51Å; F305-N341 HydrophobicContact CG-CB 3.9Å; F305-N341 WeakPolarHBondContact CG-ND2 3.38Å; F305-N341 HydrophobicContact CZ-CB 3.77Å; P306-N341 PolarHBondContact O-ND2 2.63Å; N308-N341 PolarHBondContact N-OD1 2.94Å; N341-T375 CarbonylContact C-O 3.57Å; N341-T375 WeakPolarHBondContact CA-O 3.46Å; N341-T375 WeakPolarHBondContact CB-O 3.38Å
342W97.8Very high95.2Very high1 Ų140.4 Ų40.40%0.00421%0.212CC..EExtended strand (participates in β ladder)trans-140.7134.3178.9-5594.9000110.7N308 L311 I327 W330 L369 L372 P373 T375 I377N308-W342 WeakPolarHBondContact ND2-CZ3 3.26Å; L311-W342 HydrophobicContact CD1-CD2 4.44Å; L311-W342 HydrophobicContact CD1-CE3 3.61Å; L311-W342 HydrophobicContact CD1-CZ3 4.26Å; L311-W342 HydrophobicContact CG-CE3 4.18Å; I327-W342 HydrophobicContact CB-CH2 4.11Å; I327-W342 HydrophobicContact CB-CZ3 4.44Å; I327-W342 HydrophobicContact CG1-CH2 4.11Å; I327-W342 HydrophobicContact CG1-CZ3 4.01Å; I327-W342 HydrophobicContact CG2-CH2 3.95Å; I327-W342 HydrophobicContact CG2-CZ2 4.38Å; W330-W342 HydrophobicContact CB-CH2 3.91Å; W330-W342 HydrophobicContact CB-CZ3 4.36Å; W330-W342 AromaticContact CD1-CH2 3.79Å; W330-W342 AromaticContact CD1-CZ2 3.87Å; W330-W342 AromaticContact CG-CH2 3.99Å; W330-W342 HydrophobicContact CG-CH2 3.99Å; W330-W342 HydrophobicContact CG-CZ2 4.49Å; W330-W342 HydrophobicContact CG-CZ3 4.47Å; W342-L369 HydrophobicContact CB-CD1 3.94Å; W342-L369 WeakPolarHBondContact O-CD1 3.16Å; W342-L372 HydrophobicContact CD2-CB 4.16Å; W342-L372 HydrophobicContact CD2-CD1 3.59Å; W342-L372 HydrophobicContact CD2-CG 4.47Å; W342-L372 HydrophobicContact CE3-CD1 3.85Å; W342-L372 HydrophobicContact CG-CB 4.04Å; W342-L372 HydrophobicContact CG-CD1 3.96Å; W342-L372 HydrophobicContact CH2-CD1 4.48Å; W342-L372 HydrophobicContact CZ2-CB 4.46Å; W342-L372 HydrophobicContact CZ2-CD1 4.26Å; W342-L372 HydrophobicContact CZ3-CD1 4.28Å; W342-P373 PolarHBondContact NE1-O 2.83Å; W342-T375 PolarHBondContact N-O 2.86Å; W342-I377 PolarHBondContact O-N 2.77Å
343V97.6Very high95.2Very high2 Ų234.1 Ų34.11%0.01218%0.179CC..EExtended strand (participates in β ladder)trans-130.5128.6179-166.90000108.3L307 F309 L311 V312 G345 I377L307-V343 HydrophobicContact CD2-CG2 3.65Å; F309-V343 HydrophobicContact CD1-CB 4.17Å; F309-V343 HydrophobicContact CD1-CG1 4.22Å; F309-V343 HydrophobicContact CD1-CG2 4.27Å; F309-V343 HydrophobicContact CE1-CG1 4.23Å; F309-V343 HydrophobicContact CE1-CG2 4.37Å; L311-V343 CarbonylContact C-O 3.53Å; L311-V343 WeakPolarHBondContact CB-O 3.41Å; V312-V343 HydrophobicContact CG2-CB 3.99Å; V312-V343 HydrophobicContact CG2-CG1 3.83Å; V312-V343 WeakPolarHBondContact CG2-O 3.44Å; V312-V343 PolarHBondContact N-O 3.26Å; V343-G345 WeakPolarHBondContact CG1-O 3.32Å; V343-I377 HydrophobicContact CG1-CB 4.45Å; V343-I377 HydrophobicContact CG2-CB 3.97Å; V343-I377 HydrophobicContact CG2-CG1 3.84Å
344V96.8Very high95.1Very high1 Ų131.5 Ų31.51%0.00617%0.172CC..SBendtrans-114.8-13.2176.1-63.10000113.1L311 I352 R355 L369L311-V344 HydrophobicContact CB-CG1 4.13Å; L311-V344 HydrophobicContact CD1-CG1 4.38Å; V344-I352 HydrophobicContact CB-CD1 4.5Å; V344-I352 HydrophobicContact CB-CG1 4.37Å; V344-R355 PolarHBondContact O-NH2 2.73Å; V344-L369 HydrophobicContact CG1-CB 4.24Å; V344-L369 HydrophobicContact CG1-CD1 4.35Å; V344-L369 HydrophobicContact CG2-CB 4.49Å; V344-L369 HydrophobicContact CG2-CD1 4.49Å; V344-L369 HydrophobicContact CG2-CD2 3.94Å
345G95.9Very high95.1Very high1 Ų132.6 Ų32.61%0.0118%0.176CC..  trans-160.3155-177.300000110.5V343V343-G345 WeakPolarHBondContact CG1-O 3.32Å
346N97Very high95Very high5 Ų530.9 Ų30.93%0.02716%0.164CC..  trans-160.1-174178.462.333.6000109.5Y289 D348 Q349 Y379Y289-N346 PolarHBondContact OH-ND2 2.65Å; N346-D348 VanDerWaalsContact C-N 3.34Å; N346-D348 PolarHBondContact O-N 3.2Å; N346-D348 PolarHBondContact OD1-N 2.89Å; N346-Q349 WeakPolarHBondContact OD1-CB 3.12Å; N346-Q349 WeakPolarHBondContact OD1-CG 3.32Å; N346-Q349 PolarHBondContact OD1-N 3.43Å; N346-Q349 VanDerWaalsContact OD1-N 3.07Å; N346-Y379 WeakPolarHBondContact O-CE1 3.41Å
347H96.3Very high94.8Very high2 Ų224.3 Ų24.31%0.00915%0.149CC..SBendtrans-81.1-2.4-17861.6-82.4000115.2Q24 Y26 Y74 Y379 C419 R420Q24-H347 PolarHBondContact NE2-CE1 2.83Å; Q24-H347 PolarHBondContact NE2-ND1 3.13Å; Y26-H347 HydrophobicContact CD2-CB 3.87Å; Y26-H347 HydrophobicContact CE2-CB 4.21Å; Y74-H347 AromaticContact CE2-NE2 3.94Å; Y74-H347 AromaticContact CZ-NE2 3.52Å; Y74-H347 PolarHBondContact OH-CE1 3.24Å; Y74-H347 VanDerWaalsContact OH-CE1 3.3Å; Y74-H347 PolarHBondContact OH-NE2 2.91Å; H347-Y379 WeakPolarHBondContact CA-OH 3.42Å; H347-Y379 HydrophobicContact CB-CE2 3.77Å; H347-Y379 WeakPolarHBondContact CB-OH 3.48Å; H347-C419 PolarHBondContact O-SG 3.37Å; H347-R420 HydrophobicContact CB-CG 4.38Å; H347-R420 PolarHBondContact CD2-NH2 3.43Å; H347-R420 PolarHBondContact O-NE 3.24Å; H347-R420 PolarHBondContact O-NH2 3.29Å
348D94.1Very high94.5Very high37 Ų3722.6 Ų22.620%0.19813%0.129CC..SBendtrans-108.7-12.7-178.6-62.1-43.4000113.2N346 R416 R420N346-D348 VanDerWaalsContact C-N 3.34Å; N346-D348 PolarHBondContact O-N 3.2Å; N346-D348 PolarHBondContact OD1-N 2.89Å; D348-R416 WeakPolarHBondContact OD1-CD 3.41Å; D348-R416 IonicContact OD1-NH1 3.32Å; D348-R420 IonicContact OD1-NH2 3.33Å; D348-R420 PolarHBondContact OD1-NH2 2.68Å
349Q92.9Very high94Very high75 Ų7520.2 Ų20.235%0.3512%0.12SC..SBendtrans-121.8151.5-172.2-61.2-69.7-26.100109.5V312 N346 C419V312-Q349 HydrophobicContact CG1-CB 3.85Å; V312-Q349 HydrophobicContact CG1-CG 3.59Å; N346-Q349 WeakPolarHBondContact OD1-CB 3.12Å; N346-Q349 WeakPolarHBondContact OD1-CG 3.32Å; N346-Q349 PolarHBondContact OD1-N 3.43Å; N346-Q349 VanDerWaalsContact OD1-N 3.07Å; Q349-C419 VanDerWaalsContact O-CB 3.23Å; Q349-C419 WeakPolarHBondContact O-CB 3.38Å; Q349-C419 PolarHBondContact O-SG 3.36Å
350M94.2Very high93.4Very high109 Ų10920.6 Ų20.654%0.53713%0.126SC..  trans-45.7149.1173.5-68.7-179.874.900111.3R355 D388M350-R355 HydrophobicContact CB-CG 3.91Å; M350-R355 PolarHBondContact O-NH1 2.81Å; M350-R355 PolarHBondContact O-NH2 2.66Å; M350-R355 VanDerWaalsContact O-NH2 3.12Å; M350-D388 VanDerWaalsContact CB-OD2 3.3Å; M350-D388 WeakPolarHBondContact CB-OD2 3.38Å; M350-D388 WeakPolarHBondContact CE-OD2 3.33Å
351R95.4Very high93.1Very high1 Ų121.9 Ų21.90%0.00413%0.132CC..  trans-64.2145.4177.3-74.9175.6174.3-79.60.5111.1A353 S354 R355 Y380 D382 M386 K387 D388 C419R351-A353 PolarHBondContact O-N 2.89Å; R351-S354 WeakPolarHBondContact O-CA 3.33Å; R351-S354 VanDerWaalsContact O-CB 3.3Å; R351-S354 WeakPolarHBondContact O-CB 3.48Å; R351-S354 PolarHBondContact O-N 2.64Å; R351-R355 PolarHBondContact O-N 3.29Å; R351-Y380 PolarHBondContact NH1-O 2.89Å; R351-Y380 VanDerWaalsContact NH2-CZ 3.34Å; R351-Y380 PolarHBondContact NH2-O 3.34Å; R351-Y380 PolarHBondContact NH2-OH 3.08Å; R351-D382 IonicContact NH1-OD1 3.85Å; R351-M386 WeakPolarHBondContact CD-O 3.42Å; R351-M386 PolarHBondContact NH2-SD 3.24Å; R351-K387 VanDerWaalsContact CD-C 3.41Å; R351-K387 WeakPolarHBondContact CD-O 3.47Å; R351-D388 WeakPolarHBondContact CB-OD1 3.29Å; R351-D388 WeakPolarHBondContact CG-OD1 3.35Å; R351-D388 PolarHBondContact N-OD1 3.05Å; R351-D388 PolarHBondContact N-OD2 2.93Å; R351-C419 HydrophobicContact CG-CB 3.94Å; R351-C419 PolarHBondContact NE-O 3.46Å; R351-C419 PolarHBondContact NH2-O 2.65Å
352I95.8Very high92.9Very high1 Ų121.9 Ų21.91%0.00513%0.132CC..Hα-helixtrans-58.4-37.4-178.5-175.359.1000111.6W314 V344 S354 R355 L356 A365 D382W314-I352 HydrophobicContact CB-CD1 4.44Å; W314-I352 HydrophobicContact CD2-CD1 4.47Å; W314-I352 HydrophobicContact CE3-CD1 4.22Å; V344-I352 HydrophobicContact CB-CD1 4.5Å; V344-I352 HydrophobicContact CB-CG1 4.37Å; I352-S354 VanDerWaalsContact C-N 3.27Å; I352-S354 PolarHBondContact O-N 2.79Å; I352-R355 PolarHBondContact O-N 2.76Å; I352-L356 HydrophobicContact CD1-CD1 3.9Å; I352-L356 HydrophobicContact CD1-CD2 4.35Å; I352-L356 HydrophobicContact CD1-CG 3.89Å; I352-L356 HydrophobicContact CG1-CD1 3.93Å; I352-L356 HydrophobicContact CG1-CG 4.27Å; I352-L356 WeakPolarHBondContact O-CB 3.48Å; I352-L356 VanDerWaalsContact O-CG 3.31Å; I352-L356 WeakPolarHBondContact O-CG 3.27Å; I352-L356 PolarHBondContact O-N 2.83Å; I352-A365 HydrophobicContact CG1-CB 3.9Å; I352-D382 HydrophobicContact CG2-CB 4.32Å
353A94.6Very high92.8Very high1 Ų123.3 Ų23.31%0.00814%0.139CC..Hα-helixtrans-64.8-30175.900000113.1R351 G357 A358 M386 K387R351-A353 PolarHBondContact O-N 2.89Å; A353-G357 PolarHBondContact O-N 2.78Å; A353-A358 CarbonylContact O-C 3.57Å; A353-A358 PolarHBondContact O-N 2.94Å; A353-A358 VanDerWaalsContact O-N 3.16Å; A353-M386 WeakPolarHBondContact CB-O 3.47Å; A353-K387 HydrophobicContact CB-CG 3.97Å
354S94Very high92.8Very high30 Ų3023.3 Ų23.321%0.2114%0.138CC..Hα-helixtrans-73.5-48.1172.9-510000111.4R351 I352 L356 G357 D388R351-S354 WeakPolarHBondContact O-CA 3.33Å; R351-S354 VanDerWaalsContact O-CB 3.3Å; R351-S354 WeakPolarHBondContact O-CB 3.48Å; R351-S354 PolarHBondContact O-N 2.64Å; I352-S354 VanDerWaalsContact C-N 3.27Å; I352-S354 PolarHBondContact O-N 2.79Å; S354-L356 PolarHBondContact O-N 2.77Å; S354-G357 WeakPolarHBondContact O-CA 3.32Å; S354-G357 PolarHBondContact O-N 2.77Å; S354-D388 WeakPolarHBondContact CB-OD2 3.5Å; S354-D388 WeakPolarHBondContact OG-CB 3.2Å; S354-D388 PolarHBondContact OG-N 3.3Å; S354-D388 PolarHBondContact OG-OD2 3.47Å
355R94.5Very high92.8Very high32 Ų3223.2 Ų23.212%0.12114%0.138CC..Hα-helixtrans-60.5-34179.7-75.5-164.8-69.7-89.2-17.2113V312 W314 K315 A316 V344 M350 R351 I352 G357V312-R355 PolarHBondContact O-NE 2.89Å; V312-R355 PolarHBondContact O-NH1 2.94Å; W314-R355 WeakPolarHBondContact O-CB 3.41Å; W314-R355 WeakPolarHBondContact O-CD 3.45Å; W314-R355 PolarHBondContact O-NE 3.42Å; K315-R355 WeakPolarHBondContact CA-O 3.14Å; K315-R355 HydrophobicContact CB-CB 4.49Å; A316-R355 PolarHBondContact N-O 3.06Å; V344-R355 PolarHBondContact O-NH2 2.73Å; M350-R355 HydrophobicContact CB-CG 3.91Å; M350-R355 PolarHBondContact O-NH1 2.81Å; M350-R355 PolarHBondContact O-NH2 2.66Å; M350-R355 VanDerWaalsContact O-NH2 3.12Å; R351-R355 PolarHBondContact O-N 3.29Å; I352-R355 PolarHBondContact O-N 2.76Å; R355-G357 VanDerWaalsContact C-N 3.26Å
356L93.3Very high92.9Very high6 Ų623.2 Ų23.23%0.03114%0.138CC..THydrogen-bonded Turntrans-85.12.5175.7-58.1-176.8000112.9W314 I352 S354 A358 F361 A365W314-L356 HydrophobicContact CD2-CD2 4.06Å; W314-L356 HydrophobicContact CG-CD2 4.02Å; W314-L356 HydrophobicContact CH2-CD1 4.43Å; W314-L356 HydrophobicContact CZ2-CD1 4.19Å; W314-L356 HydrophobicContact CZ2-CD2 4.38Å; I352-L356 HydrophobicContact CD1-CD1 3.9Å; I352-L356 HydrophobicContact CD1-CD2 4.35Å; I352-L356 HydrophobicContact CD1-CG 3.89Å; I352-L356 HydrophobicContact CG1-CD1 3.93Å; I352-L356 HydrophobicContact CG1-CG 4.27Å; I352-L356 WeakPolarHBondContact O-CB 3.48Å; I352-L356 VanDerWaalsContact O-CG 3.31Å; I352-L356 WeakPolarHBondContact O-CG 3.27Å; I352-L356 PolarHBondContact O-N 2.83Å; S354-L356 PolarHBondContact O-N 2.77Å; L356-A358 PolarHBondContact O-N 2.95Å; L356-A358 VanDerWaalsContact O-N 3.16Å; L356-F361 HydrophobicContact CB-CB 3.72Å; L356-F361 HydrophobicContact CB-CD2 3.97Å; L356-F361 HydrophobicContact CB-CG 3.97Å; L356-F361 HydrophobicContact CD1-CB 3.6Å; L356-F361 HydrophobicContact CD1-CG 4.36Å; L356-F361 HydrophobicContact CG-CB 4.3Å; L356-F361 WeakPolarHBondContact O-CD2 3.39Å; L356-F361 VanDerWaalsContact O-CE2 3.29Å; L356-F361 WeakPolarHBondContact O-CE2 3.43Å; L356-A365 HydrophobicContact CD1-CB 4.11Å
357G87.5Confident92.9Very high58 Ų5823 Ų2360%0.59814%0.136SC*.SBendtrans78.8-14.6174.800000115.6A353 S354 R355A353-G357 PolarHBondContact O-N 2.78Å; S354-G357 WeakPolarHBondContact O-CA 3.32Å; S354-G357 PolarHBondContact O-N 2.77Å; R355-G357 VanDerWaalsContact C-N 3.26Å
358A83.4Confident93Very high27 Ų2722.9 Ų22.922%0.22314%0.136CC..SBendtrans-162.2148.9177.300000113A353 L356 S360 F361A353-A358 CarbonylContact O-C 3.57Å; A353-A358 PolarHBondContact O-N 2.94Å; A353-A358 VanDerWaalsContact O-N 3.16Å; L356-A358 PolarHBondContact O-N 2.95Å; L356-A358 VanDerWaalsContact O-N 3.16Å; A358-S360 WeakPolarHBondContact CB-OG 2.95Å; A358-S360 PolarHBondContact O-N 3.27Å; A358-S360 VanDerWaalsContact O-N 3.07Å; A358-F361 HydrophobicContact CB-CD2 4.47Å; A358-F361 PolarHBondContact O-N 2.98Å; A358-F361 VanDerWaalsContact O-N 3.14Å
359S83.7Confident93.2Very high12 Ų1221.1 Ų21.18%0.08413%0.127CC..G310 helixtrans-62.3-14.3172.3-49.80000113.1F361 T362 G385 K387 Y464S359-F361 PolarHBondContact O-N 3.39Å; S359-F361 VanDerWaalsContact O-N 3.16Å; S359-T362 WeakPolarHBondContact O-CB 3.41Å; S359-T362 PolarHBondContact O-N 2.89Å; S359-T362 PolarHBondContact O-OG1 3.37Å; S359-G385 PolarHBondContact OG-O 3.09Å; S359-K387 WeakPolarHBondContact OG-CE 3.38Å; S359-Y464 WeakPolarHBondContact O-CE1 2.72Å; S359-Y464 VanDerWaalsContact O-CZ 3.26Å; S359-Y464 PolarHBondContact O-OH 3.29Å
360S82.8Confident93.4Very high31 Ų3117.6 Ų17.622%0.21711%0.11CC..G310 helixtrans-57.7-28.4172.752.10000112.6A358 P564A358-S360 WeakPolarHBondContact CB-OG 2.95Å; A358-S360 PolarHBondContact O-N 3.27Å; A358-S360 VanDerWaalsContact O-N 3.07Å; S360-P564 VanDerWaalsContact O-CG 3.31Å; S360-P564 WeakPolarHBondContact O-CG 3.42Å
361F91Very high93.6Very high27 Ų2712.4 Ų12.412%0.1188%0.084CC..G310 helixtrans-81.4-13.4177.3-70.8-76.5000114.5L356 A358 S359 K363 V364 A365 L516 P564L356-F361 HydrophobicContact CB-CB 3.72Å; L356-F361 HydrophobicContact CB-CD2 3.97Å; L356-F361 HydrophobicContact CB-CG 3.97Å; L356-F361 HydrophobicContact CD1-CB 3.6Å; L356-F361 HydrophobicContact CD1-CG 4.36Å; L356-F361 HydrophobicContact CG-CB 4.3Å; L356-F361 WeakPolarHBondContact O-CD2 3.39Å; L356-F361 VanDerWaalsContact O-CE2 3.29Å; L356-F361 WeakPolarHBondContact O-CE2 3.43Å; A358-F361 HydrophobicContact CB-CD2 4.47Å; A358-F361 PolarHBondContact O-N 2.98Å; A358-F361 VanDerWaalsContact O-N 3.14Å; S359-F361 PolarHBondContact O-N 3.39Å; S359-F361 VanDerWaalsContact O-N 3.16Å; F361-K363 PolarHBondContact O-N 3.09Å; F361-K363 VanDerWaalsContact O-N 3.13Å; F361-V364 PolarHBondContact O-N 3.05Å; F361-A365 PolarHBondContact O-N 3.22Å; F361-L516 WeakPolarHBondContact CE1-O 3.15Å; F361-P564 HydrophobicContact CD1-CB 4Å; F361-P564 HydrophobicContact CD1-CG 4.24Å; F361-P564 HydrophobicContact CE1-CB 4.09Å; F361-P564 HydrophobicContact CE1-CG 4.4Å
362T93.2Very high93.7Very high1 Ų112.3 Ų12.31%0.0068%0.084CC..Hα-helixtrans-51.5-40.8179.7-64.50000112.1S359 V364 A365 N366 D382 G385 Y464S359-T362 WeakPolarHBondContact O-CB 3.41Å; S359-T362 PolarHBondContact O-N 2.89Å; S359-T362 PolarHBondContact O-OG1 3.37Å; T362-V364 VanDerWaalsContact C-N 3.33Å; T362-V364 PolarHBondContact O-N 3.06Å; T362-A365 PolarHBondContact O-N 2.8Å; T362-N366 VanDerWaalsContact CG2-ND2 3.33Å; T362-N366 WeakPolarHBondContact CG2-ND2 3.44Å; T362-N366 VanDerWaalsContact O-CB 3.27Å; T362-N366 WeakPolarHBondContact O-CB 3.4Å; T362-N366 PolarHBondContact O-N 3.04Å; T362-N366 PolarHBondContact O-ND2 3.15Å; T362-D382 VanDerWaalsContact CG2-O 3.29Å; T362-D382 WeakPolarHBondContact CG2-O 3.37Å; T362-G385 WeakPolarHBondContact OG1-CA 3.15Å; T362-Y464 HydrophobicContact CG2-CD1 4.09Å; T362-Y464 HydrophobicContact CG2-CG 4.14Å
363K95.5Very high93.6Very high31 Ų3112.3 Ų12.314%0.1358%0.084CC..Hα-helixtrans-61.5-41.6178.8-65.8-168.3-179.8172.30112.4F361 A367 S462 Y464 H467 S544 V566F361-K363 PolarHBondContact O-N 3.09Å; F361-K363 VanDerWaalsContact O-N 3.13Å; K363-A367 WeakPolarHBondContact O-CB 3.18Å; K363-A367 PolarHBondContact O-N 3.1Å; K363-S462 WeakPolarHBondContact CE-O 3.43Å; K363-S462 PolarHBondContact NZ-O 3.19Å; K363-Y464 HydrophobicContact CD-CD1 4.41Å; K363-Y464 HydrophobicContact CG-CD1 3.73Å; K363-Y464 HydrophobicContact CG-CE1 4.14Å; K363-H467 WeakPolarHBondContact CA-NE2 3.26Å; K363-H467 WeakPolarHBondContact CB-NE2 3.06Å; K363-H467 HydrophobicContact CD-CB 4.25Å; K363-H467 HydrophobicContact CG-CB 4.27Å; K363-H467 PolarHBondContact O-NE2 3.49Å; K363-S544 PolarHBondContact NZ-O 2.94Å; K363-V566 HydrophobicContact CB-CG2 4.29Å; K363-V566 VanDerWaalsContact O-CG2 3.29Å; K363-V566 WeakPolarHBondContact O-CG2 3.1Å
364V96.4Very high93.7Very high1 Ų112.3 Ų12.31%0.0069%0.085CC..Hα-helixtrans-72.4-45-179.8171.90000110.9W314 F361 T362 N366 A367 L368 L514 L516 P564 V566W314-V364 HydrophobicContact CH2-CG1 4.25Å; F361-V364 PolarHBondContact O-N 3.05Å; T362-V364 VanDerWaalsContact C-N 3.33Å; T362-V364 PolarHBondContact O-N 3.06Å; V364-N366 VanDerWaalsContact C-N 3.34Å; V364-N366 PolarHBondContact O-N 2.97Å; V364-A367 PolarHBondContact O-N 2.88Å; V364-L368 PolarHBondContact O-N 3.49Å; V364-L514 HydrophobicContact CG1-CB 4.08Å; V364-L514 HydrophobicContact CG1-CD1 4.34Å; V364-L516 HydrophobicContact CG1-CD1 4.26Å; V364-L516 HydrophobicContact CG1-CG 4.01Å; V364-P564 HydrophobicContact CG2-CB 3.88Å; V364-V566 HydrophobicContact CB-CG2 4.42Å; V364-V566 HydrophobicContact CG2-CG2 3.9Å
365A97.2Very high93.8Very high0 Ų010.9 Ų10.90%08%0.075CC..Hα-helixtrans-58.7-46.517600000111.7W314 I352 L356 F361 T362 A367 L368 L369W314-A365 HydrophobicContact CH2-CB 4.19Å; W314-A365 HydrophobicContact CZ3-CB 3.88Å; I352-A365 HydrophobicContact CG1-CB 3.9Å; L356-A365 HydrophobicContact CD1-CB 4.11Å; F361-A365 PolarHBondContact O-N 3.22Å; T362-A365 PolarHBondContact O-N 2.8Å; A365-A367 PolarHBondContact O-N 3.17Å; A365-L368 PolarHBondContact O-N 3.16Å; A365-L369 WeakPolarHBondContact O-CB 3.35Å; A365-L369 PolarHBondContact O-N 3.07Å
366N97.5Very high94Very high0 Ų09.4 Ų9.40%07%0.069CC..Hα-helixtrans-66.5-35.7178.3-70.6-16.2000112.5T362 V364 L370 D382 F468 L471T362-N366 VanDerWaalsContact CG2-ND2 3.33Å; T362-N366 WeakPolarHBondContact CG2-ND2 3.44Å; T362-N366 VanDerWaalsContact O-CB 3.27Å; T362-N366 WeakPolarHBondContact O-CB 3.4Å; T362-N366 PolarHBondContact O-N 3.04Å; T362-N366 PolarHBondContact O-ND2 3.15Å; V364-N366 VanDerWaalsContact C-N 3.34Å; V364-N366 PolarHBondContact O-N 2.97Å; N366-L370 VanDerWaalsContact O-CB 3.23Å; N366-L370 WeakPolarHBondContact O-CB 3.37Å; N366-L370 WeakPolarHBondContact O-CG 3.28Å; N366-L370 PolarHBondContact O-N 2.84Å; N366-D382 PolarHBondContact ND2-O 3.02Å; N366-F468 HydrophobicContact CB-CD2 3.9Å; N366-F468 HydrophobicContact CB-CE2 4.45Å; N366-L471 HydrophobicContact CB-CD1 4.1Å
367A98.1Very high94.2Very high0 Ų09.1 Ų9.10%07%0.067CC..Hα-helixtrans-67.7-41.1175.600000112.3K363 V364 A365 L371 L471 L514 V566K363-A367 WeakPolarHBondContact O-CB 3.18Å; K363-A367 PolarHBondContact O-N 3.1Å; V364-A367 PolarHBondContact O-N 2.88Å; A365-A367 PolarHBondContact O-N 3.17Å; A367-L371 VanDerWaalsContact O-CB 3.24Å; A367-L371 WeakPolarHBondContact O-CB 3.35Å; A367-L371 WeakPolarHBondContact O-CG 3.41Å; A367-L371 PolarHBondContact O-N 2.84Å; A367-L371 VanDerWaalsContact O-N 3.12Å; A367-L471 HydrophobicContact CB-CD1 3.92Å; A367-L471 HydrophobicContact CB-CD2 4.08Å; A367-L514 HydrophobicContact CB-CD2 3.67Å; A367-V566 HydrophobicContact CB-CB 4.17Å; A367-V566 HydrophobicContact CB-CG1 3.45Å; A367-V566 VanDerWaalsContact CB-CG1 3.45Å; A367-V566 HydrophobicContact CB-CG2 3.58Å
368L97.9Very high94.7Very high1 Ų16.3 Ų6.31%0.0054%0.039CC..Hα-helixtrans-62-52.8174.4-173.262.2000110.4L311 W314 I327 V364 A365 L370 L372 L498 F500 L514L311-L368 HydrophobicContact CD1-CD2 4.38Å; W314-L368 HydrophobicContact CE3-CD2 4.31Å; W314-L368 HydrophobicContact CH2-CD2 3.94Å; W314-L368 HydrophobicContact CZ3-CB 4.44Å; W314-L368 HydrophobicContact CZ3-CD2 3.64Å; I327-L368 HydrophobicContact CD1-CD1 3.95Å; V364-L368 PolarHBondContact O-N 3.49Å; A365-L368 PolarHBondContact O-N 3.16Å; L368-L370 PolarHBondContact O-N 3.15Å; L368-L372 HydrophobicContact CD1-CD1 3.83Å; L368-L372 HydrophobicContact CD1-CD2 4.4Å; L368-L372 HydrophobicContact CD1-CG 4.04Å; L368-L372 HydrophobicContact CG-CD1 3.89Å; L368-L372 HydrophobicContact CG-CG 4.47Å; L368-L372 WeakPolarHBondContact O-CB 3.27Å; L368-L372 WeakPolarHBondContact O-CD1 3.13Å; L368-L372 WeakPolarHBondContact O-CG 3.15Å; L368-L372 PolarHBondContact O-N 3.47Å; L368-L498 HydrophobicContact CD1-CD1 4.21Å; L368-L498 HydrophobicContact CD1-CD2 4.27Å; L368-F500 HydrophobicContact CD1-CE1 4.03Å; L368-L514 HydrophobicContact CB-CD1 3.77Å; L368-L514 HydrophobicContact CD1-CD1 3.85Å; L368-L514 HydrophobicContact CG-CD1 4.35Å
369L97.8Very high95.5Very high0 Ų05.1 Ų5.10%03%0.028CC..Hα-helixtrans-53.7-53178.9172.865.5000112.4W342 V344 A365 A376 C378W342-L369 HydrophobicContact CB-CD1 3.94Å; W342-L369 WeakPolarHBondContact O-CD1 3.16Å; V344-L369 HydrophobicContact CG1-CB 4.24Å; V344-L369 HydrophobicContact CG1-CD1 4.35Å; V344-L369 HydrophobicContact CG2-CB 4.49Å; V344-L369 HydrophobicContact CG2-CD1 4.49Å; V344-L369 HydrophobicContact CG2-CD2 3.94Å; A365-L369 WeakPolarHBondContact O-CB 3.35Å; A365-L369 PolarHBondContact O-N 3.07Å; L369-A376 HydrophobicContact CD1-CB 3.88Å; L369-A376 HydrophobicContact CG-CB 3.91Å; L369-C378 HydrophobicContact CD2-CB 4.43Å
370L97.7Very high96.1Very high0 Ų04.5 Ų4.50%02%0.024CC..Hα-helixtrans-79.5-27.4-168.9-66.9178000113.7I21 N366 L368 A376 F468 L471 L472 R475I21-L370 HydrophobicContact CG2-CD2 3.75Å; N366-L370 VanDerWaalsContact O-CB 3.23Å; N366-L370 WeakPolarHBondContact O-CB 3.37Å; N366-L370 WeakPolarHBondContact O-CG 3.28Å; N366-L370 PolarHBondContact O-N 2.84Å; L368-L370 PolarHBondContact O-N 3.15Å; L370-A376 HydrophobicContact CD2-CB 3.91Å; L370-F468 HydrophobicContact CD1-CD2 3.71Å; L370-F468 HydrophobicContact CD1-CE2 3.65Å; L370-F468 HydrophobicContact CD1-CG 4.23Å; L370-F468 HydrophobicContact CD1-CZ 4.13Å; L370-F468 HydrophobicContact CD2-CE2 4.18Å; L370-F468 HydrophobicContact CD2-CZ 4.2Å; L370-F468 HydrophobicContact CG-CE2 4.17Å; L370-L471 HydrophobicContact CB-CB 4.33Å; L370-L471 HydrophobicContact CD1-CB 3.49Å; L370-L471 VanDerWaalsContact CD1-CB 3.49Å; L370-L471 HydrophobicContact CD1-CD1 4.06Å; L370-L471 HydrophobicContact CD1-CG 4.47Å; L370-L472 HydrophobicContact CD1-CD2 4.13Å; L370-L472 HydrophobicContact CD1-CG 4.26Å; L370-L472 HydrophobicContact CD2-CD2 3.74Å; L370-R475 WeakPolarHBondContact O-CD 3.11Å; L370-R475 PolarHBondContact O-NH1 2.84Å
371L97.5Very high96.8Very high0 Ų03 Ų30%01%0.014CC..Hα-helixtrans-103.4-3.8-173.5-55.1-177.5000113.8A367 L471 L474 F480 F500 R502 V512 V568A367-L371 VanDerWaalsContact O-CB 3.24Å; A367-L371 WeakPolarHBondContact O-CB 3.35Å; A367-L371 WeakPolarHBondContact O-CG 3.41Å; A367-L371 PolarHBondContact O-N 2.84Å; A367-L371 VanDerWaalsContact O-N 3.12Å; L371-L471 HydrophobicContact CD1-CD2 3.83Å; L371-L471 HydrophobicContact CG-CD2 4.23Å; L371-L474 HydrophobicContact CD2-CB 4.08Å; L371-F480 HydrophobicContact CB-CD1 4.19Å; L371-F480 HydrophobicContact CB-CE1 3.88Å; L371-F480 HydrophobicContact CD1-CE1 4.46Å; L371-F480 HydrophobicContact CD2-CD1 3.91Å; L371-F480 HydrophobicContact CD2-CE1 3.78Å; L371-F480 HydrophobicContact CD2-CG 4.43Å; L371-F480 HydrophobicContact CD2-CZ 4.18Å; L371-F480 HydrophobicContact CG-CE1 4.25Å; L371-F500 HydrophobicContact CB-CE2 4.4Å; L371-F500 HydrophobicContact CB-CZ 4.05Å; L371-F500 VanDerWaalsContact O-CE2 3.31Å; L371-F500 WeakPolarHBondContact O-CE2 3.49Å; L371-R502 PolarHBondContact O-NH1 2.94Å; L371-V512 HydrophobicContact CB-CG2 4.01Å; L371-V512 HydrophobicContact CD1-CB 4.48Å; L371-V512 HydrophobicContact CD1-CG1 3.93Å; L371-V512 HydrophobicContact CD1-CG2 3.66Å; L371-V512 HydrophobicContact CG-CG2 4.49Å; L371-V568 HydrophobicContact CD1-CG2 3.62Å
372L97.3Very high97.1Very high0 Ų01.8 Ų1.80%01%0.009CC..SBendtrans-68.1154.6162.9-77171.2000111.1L311 I327 W342 L368 V487 F500 R502L311-L372 HydrophobicContact CD1-CD1 4.2Å; I327-L372 HydrophobicContact CD1-CD1 4.17Å; I327-L372 HydrophobicContact CD1-CD2 4.14Å; I327-L372 HydrophobicContact CG1-CD1 4.1Å; I327-L372 HydrophobicContact CG1-CD2 4.29Å; I327-L372 HydrophobicContact CG2-CD2 3.82Å; W342-L372 HydrophobicContact CD2-CB 4.16Å; W342-L372 HydrophobicContact CD2-CD1 3.59Å; W342-L372 HydrophobicContact CD2-CG 4.47Å; W342-L372 HydrophobicContact CE3-CD1 3.85Å; W342-L372 HydrophobicContact CG-CB 4.04Å; W342-L372 HydrophobicContact CG-CD1 3.96Å; W342-L372 HydrophobicContact CH2-CD1 4.48Å; W342-L372 HydrophobicContact CZ2-CB 4.46Å; W342-L372 HydrophobicContact CZ2-CD1 4.26Å; W342-L372 HydrophobicContact CZ3-CD1 4.28Å; L368-L372 HydrophobicContact CD1-CD1 3.83Å; L368-L372 HydrophobicContact CD1-CD2 4.4Å; L368-L372 HydrophobicContact CD1-CG 4.04Å; L368-L372 HydrophobicContact CG-CD1 3.89Å; L368-L372 HydrophobicContact CG-CG 4.47Å; L368-L372 WeakPolarHBondContact O-CB 3.27Å; L368-L372 WeakPolarHBondContact O-CD1 3.13Å; L368-L372 WeakPolarHBondContact O-CG 3.15Å; L368-L372 PolarHBondContact O-N 3.47Å; L372-V487 HydrophobicContact CD2-CG2 4.26Å; L372-F500 HydrophobicContact CD2-CE1 4.47Å; L372-F500 HydrophobicContact CD2-CZ 4.33Å; L372-F500 HydrophobicContact CG-CZ 4.48Å; L372-R502 PolarHBondContact O-NH1 3.41Å
373P95.6Very high97.3Very high0 Ų01.8 Ų1.80%01%0.008CC..SBendtrans-75.8151.3-177.635.2-41.2000112.1S340 W342 S483 S484 V487S340-P373 WeakPolarHBondContact CB-O 3.1Å; W342-P373 PolarHBondContact NE1-O 2.83Å; P373-S483 VanDerWaalsContact CB-O 3.31Å; P373-S483 WeakPolarHBondContact CB-O 3.43Å; P373-S484 WeakPolarHBondContact CB-O 3.31Å; P373-S484 WeakPolarHBondContact CG-O 3.22Å; P373-V487 HydrophobicContact CG-CB 3.94Å; P373-V487 HydrophobicContact CG-CG1 3.9Å
374G95.8Very high97.3Very high2 Ų20.5 Ų0.52%0.0210%0.003CC..SBendtrans87.4-167.1-172.700000113.3S340 R475 S483S340-G374 CarbonylContact O-C 3.47Å; S340-G374 VanDerWaalsContact O-CA 3.22Å; S340-G374 WeakPolarHBondContact O-CA 3.38Å; G374-R475 PolarHBondContact O-NH1 3.05Å; G374-R475 VanDerWaalsContact O-NH1 3.14Å; G374-R475 PolarHBondContact O-NH2 2.64Å; G374-S483 PolarHBondContact N-O 2.9Å
375T96.9Very high97.3Very high0 Ų00.5 Ų0.50%00%0.003CC..EExtended strand (participates in β ladder)trans-86.9124.2-171.6-57.30000112.4W17 I22 F305 W339 S340 N341 W342 I377W17-T375 PolarHBondContact O-OG1 2.95Å; I22-T375 HydrophobicContact CD1-CG2 4.11Å; I22-T375 HydrophobicContact CG1-CG2 3.96Å; F305-T375 HydrophobicContact CE1-CG2 4.18Å; F305-T375 HydrophobicContact CZ-CG2 4.02Å; W339-T375 PolarHBondContact NE1-OG1 3.26Å; S340-T375 PolarHBondContact O-N 2.6Å; N341-T375 CarbonylContact C-O 3.57Å; N341-T375 WeakPolarHBondContact CA-O 3.46Å; N341-T375 WeakPolarHBondContact CB-O 3.38Å; W342-T375 PolarHBondContact N-O 2.86Å; T375-I377 HydrophobicContact CG2-CD1 4.13Å
376A97.6Very high97.1Very high0 Ų01.1 Ų1.10%01%0.006CC..EExtended strand (participates in β ladder)trans-83.7136.6172.800000110.7I21 I22 L369 L370I21-A376 WeakPolarHBondContact CA-O 3.47Å; I21-A376 HydrophobicContact CB-CB 4.37Å; I21-A376 WeakPolarHBondContact CB-O 3.3Å; I21-A376 HydrophobicContact CG2-CB 3.87Å; I22-A376 PolarHBondContact N-O 3.3Å; L369-A376 HydrophobicContact CD1-CB 3.88Å; L369-A376 HydrophobicContact CG-CB 3.91Å; L370-A376 HydrophobicContact CD2-CB 3.91Å
377I98.1Very high96.9Very high0 Ų05.5 Ų5.50%03%0.025CC..EExtended strand (participates in β ladder)trans-109.4118.6173.1-44.5-59.8000108.2I22 W60 F305 L307 W342 V343 T375I22-I377 HydrophobicContact CB-CD1 3.68Å; I22-I377 HydrophobicContact CD1-CD1 3.79Å; I22-I377 HydrophobicContact CG1-CD1 4.05Å; I22-I377 HydrophobicContact CG2-CD1 4.42Å; I22-I377 WeakPolarHBondContact O-CA 3.11Å; W60-I377 HydrophobicContact CE3-CG2 4.18Å; W60-I377 HydrophobicContact CZ3-CG2 4.13Å; F305-I377 HydrophobicContact CE2-CD1 4.24Å; F305-I377 HydrophobicContact CZ-CD1 4.1Å; L307-I377 HydrophobicContact CD2-CD1 4.42Å; L307-I377 HydrophobicContact CD2-CG1 3.89Å; W342-I377 PolarHBondContact O-N 2.77Å; V343-I377 HydrophobicContact CG1-CB 4.45Å; V343-I377 HydrophobicContact CG2-CB 3.97Å; V343-I377 HydrophobicContact CG2-CG1 3.84Å; T375-I377 HydrophobicContact CG2-CD1 4.13Å
378C98.3Very high96.7Very high0 Ų07.1 Ų7.10%03%0.034CC..EExtended strand (participates in β ladder)trans-112.7126.2-178.6-1750000109.7I21 I22 Y23 Q24 L369 F468I21-C378 HydrophobicContact CD1-CB 3.98Å; I22-C378 PolarHBondContact O-N 2.98Å; Y23-C378 CarbonylContact C-O 3.5Å; Y23-C378 WeakPolarHBondContact CA-O 3.36Å; Y23-C378 HydrophobicContact CD2-CB 4.37Å; Q24-C378 PolarHBondContact N-O 3.13Å; L369-C378 HydrophobicContact CD2-CB 4.43Å; C378-F468 HydrophobicContact CB-CZ 4.13Å; C378-F468 VanDerWaalsContact SG-CZ 3.57Å
379Y98.5Very high96.5Very high1 Ų17.6 Ų7.60%0.0044%0.037CC..EExtended strand (participates in β ladder)trans-82.3141.2171-174.6-129.7000110.7Q24 N346 H347 G381 D382 C419Q24-Y379 HydrophobicContact CB-CD2 4.21Å; Q24-Y379 HydrophobicContact CG-CD2 3.93Å; Q24-Y379 HydrophobicContact CG-CE2 4.4Å; Q24-Y379 VanDerWaalsContact OE1-CD2 3.31Å; N346-Y379 WeakPolarHBondContact O-CE1 3.41Å; H347-Y379 WeakPolarHBondContact CA-OH 3.42Å; H347-Y379 HydrophobicContact CB-CE2 3.77Å; H347-Y379 WeakPolarHBondContact CB-OH 3.48Å; Y379-G381 PolarHBondContact O-N 3.24Å; Y379-D382 VanDerWaalsContact O-CB 3.29Å; Y379-D382 WeakPolarHBondContact O-CB 3.43Å; Y379-D382 PolarHBondContact O-N 2.93Å; Y379-D382 VanDerWaalsContact O-N 3.07Å; Y379-C419 PolarHBondContact OH-O 2.97Å
380Y98.2Very high96.1Very high0 Ų014.2 Ų14.20%07%0.068CC..THydrogen-bonded Turntrans-56.4137.9-177.283.3-78.1000112Y23 Q24 S29 F30 R351 D382 R420 A421 L423Y23-Y380 WeakPolarHBondContact OH-CA 3.13Å; Y23-Y380 WeakPolarHBondContact OH-CB 3.37Å; Q24-Y380 WeakPolarHBondContact O-CB 3.48Å; Q24-Y380 PolarHBondContact O-N 2.82Å; S29-Y380 WeakPolarHBondContact CB-OH 3.26Å; F30-Y380 HydrophobicContact CD2-CD2 4.49Å; R351-Y380 PolarHBondContact NH1-O 2.89Å; R351-Y380 VanDerWaalsContact NH2-CZ 3.34Å; R351-Y380 PolarHBondContact NH2-O 3.34Å; R351-Y380 PolarHBondContact NH2-OH 3.08Å; Y380-D382 VanDerWaalsContact C-N 3.26Å; Y380-D382 PolarHBondContact O-N 3.32Å; Y380-R420 PolarHBondContact OH-O 3.2Å; Y380-A421 PolarHBondContact OH-O 2.93Å; Y380-L423 HydrophobicContact CD2-CB 4.01Å; Y380-L423 HydrophobicContact CD2-CD1 3.93Å; Y380-L423 HydrophobicContact CD2-CD2 4.29Å; Y380-L423 HydrophobicContact CD2-CG 4.3Å; Y380-L423 HydrophobicContact CE2-CB 3.99Å; Y380-L423 HydrophobicContact CE2-CD1 4.36Å
381G96.8Very high95.8Very high0 Ų014.6 Ų14.60%07%0.07CC..THydrogen-bonded Turntrans84.3-15.9-17700000114.3Y379 E383 L384 G385 M386Y379-G381 PolarHBondContact O-N 3.24Å; G381-E383 VanDerWaalsContact C-N 3.25Å; G381-E383 WeakPolarHBondContact CA-OE2 3.36Å; G381-E383 PolarHBondContact N-OE1 3.43Å; G381-E383 PolarHBondContact N-OE2 3.21Å; G381-E383 PolarHBondContact O-N 3.21Å; G381-L384 CarbonylContact O-C 3.5Å; G381-L384 WeakPolarHBondContact O-CA 3.41Å; G381-L384 WeakPolarHBondContact O-CB 3.31Å; G381-L384 PolarHBondContact O-N 2.83Å; G381-G385 PolarHBondContact O-N 3.31Å; G381-G385 VanDerWaalsContact O-N 3.13Å; G381-M386 WeakPolarHBondContact O-CB 3.27Å; G381-M386 PolarHBondContact O-N 3.15Å
382D97Very high95.5Very high1 Ų116.3 Ų16.31%0.0058%0.081CC..G310 helixtrans-66.8-30.3174.1-75.1-6.2000111.3R351 I352 T362 N366 Y379 Y380 L384 G385R351-D382 IonicContact NH1-OD1 3.85Å; I352-D382 HydrophobicContact CG2-CB 4.32Å; T362-D382 VanDerWaalsContact CG2-O 3.29Å; T362-D382 WeakPolarHBondContact CG2-O 3.37Å; N366-D382 PolarHBondContact ND2-O 3.02Å; Y379-D382 VanDerWaalsContact O-CB 3.29Å; Y379-D382 WeakPolarHBondContact O-CB 3.43Å; Y379-D382 PolarHBondContact O-N 2.93Å; Y379-D382 VanDerWaalsContact O-N 3.07Å; Y380-D382 VanDerWaalsContact C-N 3.26Å; Y380-D382 PolarHBondContact O-N 3.32Å; D382-L384 PolarHBondContact O-N 2.88Å; D382-G385 PolarHBondContact O-N 3.49Å
383E97.6Very high95Very high0 Ų020.8 Ų20.80%010%0.104CC..G310 helixtrans-64.7-27.2170.677.4-73.1-177.300112.8Y23 Y50 G381 Y464 L465 F468Y23-E383 HydrophobicContact CE2-CG 4.49Å; Y23-E383 PolarHBondContact OH-OE1 3.48Å; Y23-E383 PolarHBondContact OH-OE2 2.98Å; Y50-E383 PolarHBondContact OH-OE1 2.88Å; Y50-E383 VanDerWaalsContact OH-OE1 3.04Å; G381-E383 VanDerWaalsContact C-N 3.25Å; G381-E383 WeakPolarHBondContact CA-OE2 3.36Å; G381-E383 PolarHBondContact N-OE1 3.43Å; G381-E383 PolarHBondContact N-OE2 3.21Å; G381-E383 PolarHBondContact O-N 3.21Å; E383-Y464 CarbonylContact O-C 3.55Å; E383-Y464 WeakPolarHBondContact O-CB 3.43Å; E383-L465 HydrophobicContact CB-CD1 4.5Å; E383-L465 HydrophobicContact CG-CD1 3.72Å; E383-L465 PolarHBondContact O-N 2.94Å; E383-F468 HydrophobicContact CB-CB 4.04Å; E383-F468 HydrophobicContact CB-CD1 3.64Å; E383-F468 HydrophobicContact CB-CD2 3.71Å; E383-F468 HydrophobicContact CB-CE1 3.9Å; E383-F468 HydrophobicContact CB-CE2 3.98Å; E383-F468 HydrophobicContact CB-CG 3.54Å; E383-F468 HydrophobicContact CB-CZ 4.07Å
384L96Very high94.7Very high4 Ų428.5 Ų28.52%0.02114%0.14CC..G310 helixtrans-87.1-13178.1-59.2179.9000112.4G381 D382 M386 L423 L452 V454 Q457 Y464 L465G381-L384 CarbonylContact O-C 3.5Å; G381-L384 WeakPolarHBondContact O-CA 3.41Å; G381-L384 WeakPolarHBondContact O-CB 3.31Å; G381-L384 PolarHBondContact O-N 2.83Å; D382-L384 PolarHBondContact O-N 2.88Å; L384-M386 VanDerWaalsContact C-N 3.35Å; L384-L423 HydrophobicContact CD1-CD1 3.45Å; L384-L423 VanDerWaalsContact CD1-CD1 3.45Å; L384-L423 HydrophobicContact CD1-CG 4.33Å; L384-L452 VanDerWaalsContact O-CD1 3.31Å; L384-L452 WeakPolarHBondContact O-CD1 3.21Å; L384-V454 HydrophobicContact CD1-CG2 3.81Å; L384-V454 HydrophobicContact CD2-CG2 4.18Å; L384-Q457 PolarHBondContact O-NE2 3.39Å; L384-Y464 VanDerWaalsContact O-CD2 3.28Å; L384-Y464 WeakPolarHBondContact O-CD2 3.45Å; L384-L465 HydrophobicContact CD2-CB 4.01Å; L384-L465 HydrophobicContact CD2-CD1 3.87Å; L384-L465 HydrophobicContact CD2-CD2 4.06Å; L384-L465 HydrophobicContact CD2-CG 4.2Å
385G94.8Very high94.5Very high1 Ų129.7 Ų29.71%0.0115%0.149CC..THydrogen-bonded Turntrans73.329.4-170.900000113.4S359 T362 G381 D382S359-G385 PolarHBondContact OG-O 3.09Å; T362-G385 WeakPolarHBondContact OG1-CA 3.15Å; G381-G385 PolarHBondContact O-N 3.31Å; G381-G385 VanDerWaalsContact O-N 3.13Å; D382-G385 PolarHBondContact O-N 3.49Å
386M94.5Very high94.3Very high13 Ų1330.7 Ų30.76%0.06416%0.155CC..PPolyproline II helixtrans-57.9134.4175.9-171.3169.5172.400110.3R351 A353 G381 L384 V389 A421 L423R351-M386 WeakPolarHBondContact CD-O 3.42Å; R351-M386 PolarHBondContact NH2-SD 3.24Å; A353-M386 WeakPolarHBondContact CB-O 3.47Å; G381-M386 WeakPolarHBondContact O-CB 3.27Å; G381-M386 PolarHBondContact O-N 3.15Å; L384-M386 VanDerWaalsContact C-N 3.35Å; M386-V389 HydrophobicContact CE-CG2 4.43Å; M386-A421 HydrophobicContact CE-CB 3.83Å; M386-A421 WeakPolarHBondContact CE-O 3.41Å; M386-L423 HydrophobicContact SD-CD1 4.34Å
387K93.5Very high94.2Very high92 Ų9235.3 Ų35.340%0.418%0.175SC..PPolyproline II helixtrans-101165.6173.2-63.5-178.4-176.4179.70109.5R351 A353 S359 V389R351-K387 VanDerWaalsContact CD-C 3.41Å; R351-K387 WeakPolarHBondContact CD-O 3.47Å; A353-K387 HydrophobicContact CB-CG 3.97Å; S359-K387 WeakPolarHBondContact OG-CE 3.38Å; K387-V389 PolarHBondContact O-N 3.04Å
388D93.4Very high94Very high35 Ų3535.3 Ų35.319%0.18718%0.175CC..PPolyproline II helixtrans-56.9137.4168-66.9-28.8000109.5M350 R351 S354 P418 C419M350-D388 VanDerWaalsContact CB-OD2 3.3Å; M350-D388 WeakPolarHBondContact CB-OD2 3.38Å; M350-D388 WeakPolarHBondContact CE-OD2 3.33Å; R351-D388 WeakPolarHBondContact CB-OD1 3.29Å; R351-D388 WeakPolarHBondContact CG-OD1 3.35Å; R351-D388 PolarHBondContact N-OD1 3.05Å; R351-D388 PolarHBondContact N-OD2 2.93Å; S354-D388 WeakPolarHBondContact CB-OD2 3.5Å; S354-D388 WeakPolarHBondContact OG-CB 3.2Å; S354-D388 PolarHBondContact OG-N 3.3Å; S354-D388 PolarHBondContact OG-OD2 3.47Å; D388-P418 WeakPolarHBondContact CA-O 3.46Å; D388-P418 HydrophobicContact CB-CB 3.75Å; D388-C419 WeakPolarHBondContact OD1-CA 3.39Å; D388-C419 WeakPolarHBondContact OD1-CB 3.33Å
389V92.7Very high93.6Very high10 Ų1036.2 Ų36.26%0.06118%0.18CC..PPolyproline II helixtrans-89139.9176.1176.90000109.3M386 K387 V391 P418 A421 P444 M445 T446M386-V389 HydrophobicContact CE-CG2 4.43Å; K387-V389 PolarHBondContact O-N 3.04Å; V389-V391 PolarHBondContact O-N 3.37Å; V389-P418 PolarHBondContact N-O 3.44Å; V389-P418 VanDerWaalsContact O-CB 3.31Å; V389-P418 WeakPolarHBondContact O-CB 3.37Å; V389-A421 HydrophobicContact CB-CB 3.71Å; V389-A421 HydrophobicContact CG2-CB 3.4Å; V389-P444 HydrophobicContact CG1-CB 4.11Å; V389-P444 WeakPolarHBondContact CG1-O 3.45Å; V389-M445 WeakPolarHBondContact CG1-O 3.19Å; V389-T446 WeakPolarHBondContact CG2-OG1 3.37Å
390H90.8Very high93Very high140 Ų14037.9 Ų37.965%0.64819%0.187SC*.PPolyproline II helixtrans-67.1119.1169.9175.763.8000110
391V91.6Very high92.4Very high8 Ų838 Ų385%0.04819%0.188CC..  trans-106.9113.6175.6-175.40000107.7V389 A395 I396 D417 P418 P444V389-V391 PolarHBondContact O-N 3.37Å; V391-A395 HydrophobicContact CG1-CB 4.09Å; V391-I396 HydrophobicContact CG1-CG1 3.86Å; V391-D417 HydrophobicContact CG1-CB 4.4Å; V391-D417 HydrophobicContact CG2-CB 3.98Å; V391-P418 HydrophobicContact CG2-CG 4.21Å; V391-P444 HydrophobicContact CG1-CG 4.29Å
392P89.8Confident91.9Very high36 Ų3642.3 Ų42.323%0.23421%0.21CC..  trans-69.6156.617632.5-36.5000110.3E394 A395 I396P392-E394 WeakPolarHBondContact CB-OE1 3.26Å; P392-E394 PolarHBondContact O-N 3.3Å; P392-E394 VanDerWaalsContact O-N 3.17Å; P392-A395 HydrophobicContact CG-CB 3.73Å; P392-A395 WeakPolarHBondContact O-CA 3.49Å; P392-A395 PolarHBondContact O-N 2.84Å; P392-I396 PolarHBondContact O-N 3.31Å
393I88.2Confident91Very high94 Ų9447.7 Ų47.748%0.48223%0.23SC..G310 helixtrans-52.9-43.5-170.6-72.8167.2000112.1A395 I396 L405I393-A395 PolarHBondContact O-N 2.89Å; I393-I396 PolarHBondContact O-N 3.22Å; I393-L405 HydrophobicContact CG2-CD1 4.29Å
394E89.2Confident89.9Confident162 Ų16251.2 Ų51.276%0.75725%0.249SC*.G310 helixtrans-68.5-15.8-179.766.6-83.5-168.400114.3P392P392-E394 WeakPolarHBondContact CB-OE1 3.26Å; P392-E394 PolarHBondContact O-N 3.3Å; P392-E394 VanDerWaalsContact O-N 3.17Å
395A92Very high88.8Confident26 Ų2652.4 Ų52.422%0.21526%0.256CS..G310 helixtrans-103.60.6-179.600000113.4V391 P392 I393 K397 P444V391-A395 HydrophobicContact CG1-CB 4.09Å; P392-A395 HydrophobicContact CG-CB 3.73Å; P392-A395 WeakPolarHBondContact O-CA 3.49Å; P392-A395 PolarHBondContact O-N 2.84Å; I393-A395 PolarHBondContact O-N 2.89Å; A395-K397 PolarHBondContact O-N 3.04Å; A395-P444 HydrophobicContact CB-CG 3.94Å
396I92.2Very high87.5Confident22 Ų2256.6 Ų56.611%0.11329%0.29CS..  trans-68.4132.2177.5-63.4166.3000109.1V391 P392 I393 I402 L405 D417V391-I396 HydrophobicContact CG1-CG1 3.86Å; P392-I396 PolarHBondContact O-N 3.31Å; I393-I396 PolarHBondContact O-N 3.22Å; I396-I402 HydrophobicContact CG2-CG1 3.94Å; I396-L405 HydrophobicContact CD1-CD1 3.23Å; I396-D417 WeakPolarHBondContact CA-OD2 3.38Å
397K94Very high85.9Confident96 Ų9659.6 Ų59.642%0.41733%0.325SS..  trans-120.4-25.6178.8-64.9-172.3173.2-175.10112F72 A395 D417 W442 L443F72-K397 HydrophobicContact CE1-CB 4.12Å; F72-K397 HydrophobicContact CZ-CB 3.74Å; F72-K397 WeakPolarHBondContact CZ-O 3.34Å; A395-K397 PolarHBondContact O-N 3.04Å; K397-D417 PolarHBondContact N-OD2 3.43Å; K397-W442 HydrophobicContact CD-CE3 3.95Å; K397-W442 HydrophobicContact CD-CZ3 4.35Å; K397-W442 WeakPolarHBondContact CD-O 3.38Å; K397-W442 WeakPolarHBondContact CE-O 3.3Å; K397-W442 PolarHBondContact NZ-O 3.17Å; K397-L443 HydrophobicContact CB-CD2 4.48Å; K397-L443 HydrophobicContact CD-CD2 4.3Å; K397-L443 HydrophobicContact CG-CD2 4.37Å
398D93.9Very high84.3Confident0 Ų059 Ų590%033%0.326CS..  trans-64.5125.3-177.6178.946.9000111F72 Y400 G401 I402 G415 R416 D417 R420F72-D398 HydrophobicContact CE2-CB 4.24Å; D398-Y400 PolarHBondContact O-N 3.21Å; D398-Y400 WeakPolarHBondContact OD2-CB 3.32Å; D398-G401 WeakPolarHBondContact O-CA 3.46Å; D398-G401 PolarHBondContact O-N 3.13Å; D398-G401 PolarHBondContact OD2-N 3.03Å; D398-I402 WeakPolarHBondContact O-CG1 3.32Å; D398-I402 PolarHBondContact O-N 3.38Å; D398-G415 WeakPolarHBondContact OD2-CA 2.92Å; D398-R416 IonicContact OD1-CZ 2.66Å; D398-R416 IonicContact OD1-NE 3.69Å; D398-R416 PolarHBondContact OD1-NE 3.45Å; D398-R416 VanDerWaalsContact OD1-NE 3.09Å; D398-R416 IonicContact OD1-NH2 3.9Å; D398-R416 PolarHBondContact OD1-NH2 3.33Å; D398-R416 PolarHBondContact OD2-N 2.91Å; D398-R416 IonicContact OD2-NE 2.73Å; D398-D417 WeakPolarHBondContact CB-OD1 3.24Å; D398-D417 WeakPolarHBondContact CB-OD2 3.28Å; D398-D417 PolarHBondContact N-OD1 3.45Å; D398-D417 PolarHBondContact N-OD2 3.24Å; D398-R420 IonicContact OD1-NH1 3.07Å
399P90Very high82.6Confident19 Ų1961.4 Ų61.412%0.12335%0.345CS..Hα-helixtrans-60.5-29.6-177.521.7-33.9000113V70 L179 R403V70-P399 WeakPolarHBondContact O-CG 3.4Å; L179-P399 HydrophobicContact CD1-CB 4.09Å; L179-P399 HydrophobicContact CD1-CG 3.84Å; L179-P399 HydrophobicContact CD2-CB 4.02Å; L179-P399 HydrophobicContact CD2-CG 4.42Å; P399-R403 VanDerWaalsContact O-CB 3.32Å; P399-R403 WeakPolarHBondContact O-CB 3.24Å; P399-R403 PolarHBondContact O-N 3.3Å
400Y86Confident81Confident37 Ų3767.8 Ų67.815%0.14538%0.379CS..Hα-helixtrans-66-45.2173.8-64.4-116.7000110.8I159 F178 D398 N404 R416I159-Y400 HydrophobicContact CB-CD1 4.06Å; I159-Y400 HydrophobicContact CB-CE1 3.79Å; I159-Y400 HydrophobicContact CD1-CD1 3.94Å; I159-Y400 HydrophobicContact CD1-CD2 3.76Å; I159-Y400 HydrophobicContact CD1-CE1 4.22Å; I159-Y400 HydrophobicContact CD1-CE2 4.03Å; I159-Y400 HydrophobicContact CD1-CG 3.69Å; I159-Y400 HydrophobicContact CG1-CD1 3.7Å; I159-Y400 HydrophobicContact CG1-CD2 4.44Å; I159-Y400 HydrophobicContact CG1-CE1 3.95Å; I159-Y400 HydrophobicContact CG1-CG 3.95Å; F178-Y400 WeakPolarHBondContact CD1-OH 3.32Å; D398-Y400 PolarHBondContact O-N 3.21Å; D398-Y400 WeakPolarHBondContact OD2-CB 3.32Å; Y400-N404 WeakPolarHBondContact O-CB 3.46Å; Y400-N404 VanDerWaalsContact O-CG 3.27Å; Y400-N404 PolarHBondContact O-N 2.76Å; Y400-N404 VanDerWaalsContact O-N 3.12Å; Y400-N404 PolarHBondContact O-ND2 2.99Å; Y400-R416 VanDerWaalsContact CE2-CZ 3.48Å
401G86Confident79.3Confident2 Ų262 Ų622%0.02136%0.356CS..Hα-helixtrans-57.9-52.2172.200000113.1D398 R403 N404 L405 T414D398-G401 WeakPolarHBondContact O-CA 3.46Å; D398-G401 PolarHBondContact O-N 3.13Å; D398-G401 PolarHBondContact OD2-N 3.03Å; G401-R403 VanDerWaalsContact C-N 3.34Å; G401-R403 PolarHBondContact O-N 3.4Å; G401-N404 PolarHBondContact O-N 3.47Å; G401-L405 WeakPolarHBondContact O-CG 3.42Å; G401-L405 PolarHBondContact O-N 2.83Å; G401-T414 WeakPolarHBondContact CA-O 3.25Å; G401-T414 PolarHBondContact N-O 3.28Å
402I87.5Confident77.6Confident91 Ų9166.4 Ų66.447%0.46738%0.384SS..Hα-helixtrans-59.2-45-178.1-65.4171.6000111I396 D398 L405 A406I396-I402 HydrophobicContact CG2-CG1 3.94Å; D398-I402 WeakPolarHBondContact O-CG1 3.32Å; D398-I402 PolarHBondContact O-N 3.38Å; I402-L405 PolarHBondContact O-N 2.84Å; I402-A406 PolarHBondContact O-N 3.09Å
403R78.2Confident75.9Confident113 Ų11368.7 Ų68.743%0.42639%0.392SS..Hα-helixtrans-66.8-43.4-178.5-169.2-175.8-172.8174.4-3.1112.5I159 G160 P399 G401 L405 A406I159-R403 HydrophobicContact CD1-CB 4.49Å; I159-R403 PolarHBondContact O-NH1 3.45Å; I159-R403 VanDerWaalsContact O-NH1 3.08Å; G160-R403 PolarHBondContact O-NH1 2.82Å; G160-R403 PolarHBondContact O-NH2 2.94Å; P399-R403 VanDerWaalsContact O-CB 3.32Å; P399-R403 WeakPolarHBondContact O-CB 3.24Å; P399-R403 PolarHBondContact O-N 3.3Å; G401-R403 VanDerWaalsContact C-N 3.34Å; G401-R403 PolarHBondContact O-N 3.4Å; R403-L405 PolarHBondContact O-N 2.83Å; R403-A406 WeakPolarHBondContact O-CB 3.48Å; R403-A406 PolarHBondContact O-N 2.95Å; R403-A406 VanDerWaalsContact O-N 3.14Å
404N73.7Confident75Confident74 Ų7467.1 Ų67.140%0.39639%0.387SS..Hα-helixtrans-62.6-32.8179.3-75-39.8000112Y400 G401 T414Y400-N404 WeakPolarHBondContact O-CB 3.46Å; Y400-N404 VanDerWaalsContact O-CG 3.27Å; Y400-N404 PolarHBondContact O-N 2.76Å; Y400-N404 VanDerWaalsContact O-N 3.12Å; Y400-N404 PolarHBondContact O-ND2 2.99Å; G401-N404 PolarHBondContact O-N 3.47Å; N404-T414 WeakPolarHBondContact CB-OG1 3.46Å; N404-T414 VanDerWaalsContact CG-OG1 3.23Å; N404-T414 PolarHBondContact ND2-O 3.06Å; N404-T414 PolarHBondContact ND2-OG1 2.95Å
405L72.6Confident74.8Confident29 Ų2961 Ų6115%0.15237%0.367CS..Hα-helixtrans-77.2-23.5175.9-68.9172.8000114.1I393 I396 G401 I402 R403 G407 N408I393-L405 HydrophobicContact CG2-CD1 4.29Å; I396-L405 HydrophobicContact CD1-CD1 3.23Å; G401-L405 WeakPolarHBondContact O-CG 3.42Å; G401-L405 PolarHBondContact O-N 2.83Å; I402-L405 PolarHBondContact O-N 2.84Å; R403-L405 PolarHBondContact O-N 2.83Å; L405-G407 PolarHBondContact O-N 3.45Å; L405-N408 PolarHBondContact O-N 3.17Å; L405-N408 VanDerWaalsContact O-N 3.12Å
406A68.7Low74.9Confident89 Ų8961 Ų6174%0.73636%0.362SS*.THydrogen-bonded Turntrans-62.1-5-174.300000115I402 R403I402-A406 PolarHBondContact O-N 3.09Å; R403-A406 WeakPolarHBondContact O-CB 3.48Å; R403-A406 PolarHBondContact O-N 2.95Å; R403-A406 VanDerWaalsContact O-N 3.14Å
407G59.1Low75.1Confident77 Ų7760 Ų6079%0.79436%0.357SS*.THydrogen-bonded Turntrans-127.4-7.1173.400000115.8L405L405-G407 PolarHBondContact O-N 3.45Å
408N60Low75.1Confident79 Ų7956.9 Ų56.942%0.42235%0.346SS..  trans-163.1106-176.6-176.95000111.1L405 D410 A411L405-N408 PolarHBondContact O-N 3.17Å; L405-N408 VanDerWaalsContact O-N 3.12Å; N408-D410 PolarHBondContact O-N 3.13Å; N408-D410 WeakPolarHBondContact OD1-CA 3.12Å; N408-D410 WeakPolarHBondContact OD1-CB 2.95Å; N408-D410 PolarHBondContact OD1-N 3.39Å; N408-A411 HydrophobicContact CB-CB 4.08Å; N408-A411 VanDerWaalsContact O-CB 3.24Å; N408-A411 WeakPolarHBondContact O-CB 3.47Å; N408-A411 PolarHBondContact O-N 3.16Å; N408-A411 VanDerWaalsContact O-N 3.08Å; N408-A411 PolarHBondContact OD1-N 2.93Å
409S58.4Low75.2Confident85 Ų8557 Ų5759%0.59435%0.347SS*.THydrogen-bonded Turntrans-66.4-18.4176.154.40000113.8
410D58.3Low75.5Confident144 Ų14456.1 Ų56.177%0.7734%0.342SS*.THydrogen-bonded Turntrans-92.21.8175.7-59.2-35.5000112.4N408N408-D410 PolarHBondContact O-N 3.13Å; N408-D410 WeakPolarHBondContact OD1-CA 3.12Å; N408-D410 WeakPolarHBondContact OD1-CB 2.95Å; N408-D410 PolarHBondContact OD1-N 3.39Å
411A55.2Low76Confident19 Ų1954.4 Ų54.416%0.15734%0.335CS..SBendtrans-60.3142.8173.200000109.9N408 Q413N408-A411 HydrophobicContact CB-CB 4.08Å; N408-A411 VanDerWaalsContact O-CB 3.24Å; N408-A411 WeakPolarHBondContact O-CB 3.47Å; N408-A411 PolarHBondContact O-N 3.16Å; N408-A411 VanDerWaalsContact O-N 3.08Å; N408-A411 PolarHBondContact OD1-N 2.93Å; A411-Q413 PolarHBondContact O-N 3.21Å
412P56.4Low76.5Confident100 Ų10054.5 Ų54.565%0.64934%0.335SS*.  trans-54142.5171.321.7-29.8000109.4T414P412-T414 VanDerWaalsContact C-N 3.29Å; P412-T414 HydrophobicContact CB-CG2 4.38Å; P412-T414 HydrophobicContact CG-CG2 4.14Å; P412-T414 PolarHBondContact O-N 3.09Å; P412-T414 PolarHBondContact O-OG1 3.27Å
413Q55.2Low76.9Confident84 Ų8450.2 Ų50.239%0.39331%0.313SS..  trans-63.292.1174.5-69.9-61.7-24.300109.4A411A411-Q413 PolarHBondContact O-N 3.21Å
414T69.5Low77.8Confident61 Ų6145.5 Ų45.537%0.37430%0.298SS..  trans-103.7100.2-179.647.90000108.4G401 N404 P412G401-T414 WeakPolarHBondContact CA-O 3.25Å; G401-T414 PolarHBondContact N-O 3.28Å; N404-T414 WeakPolarHBondContact CB-OG1 3.46Å; N404-T414 VanDerWaalsContact CG-OG1 3.23Å; N404-T414 PolarHBondContact ND2-O 3.06Å; N404-T414 PolarHBondContact ND2-OG1 2.95Å; P412-T414 VanDerWaalsContact C-N 3.29Å; P412-T414 HydrophobicContact CB-CG2 4.38Å; P412-T414 HydrophobicContact CG-CG2 4.14Å; P412-T414 PolarHBondContact O-N 3.09Å; P412-T414 PolarHBondContact O-OG1 3.27Å
415G84.7Confident78.9Confident34 Ų3442.6 Ų42.635%0.35128%0.282SS..SBendtrans-175.3174.7179.300000111.3D398D398-G415 WeakPolarHBondContact OD2-CA 2.92Å
416R93.9Very high79.9Confident25 Ų2542.8 Ų42.89%0.09428%0.283CS..SBendtrans-99.8-8-172.2-58.3168.3-62.8166.24.3113.1D71 D348 D398 Y400 P418 C419 R420D71-R416 IonicContact OD1-CZ 3.75Å; D71-R416 IonicContact OD1-NH1 2.69Å; D71-R416 IonicContact OD1-NH2 2.89Å; D71-R416 PolarHBondContact OD1-NH2 2.63Å; D71-R416 IonicContact OD2-NH1 2.65Å; D71-R416 IonicContact OD2-NH2 3.86Å; D348-R416 WeakPolarHBondContact OD1-CD 3.41Å; D348-R416 IonicContact OD1-NH1 3.32Å; D398-R416 IonicContact OD1-CZ 2.66Å; D398-R416 IonicContact OD1-NE 3.69Å; D398-R416 PolarHBondContact OD1-NE 3.45Å; D398-R416 VanDerWaalsContact OD1-NE 3.09Å; D398-R416 IonicContact OD1-NH2 3.9Å; D398-R416 PolarHBondContact OD1-NH2 3.33Å; D398-R416 PolarHBondContact OD2-N 2.91Å; D398-R416 IonicContact OD2-NE 2.73Å; Y400-R416 VanDerWaalsContact CE2-CZ 3.48Å; R416-P418 VanDerWaalsContact C-CD 3.47Å; R416-C419 PolarHBondContact O-N 2.88Å; R416-C419 PolarHBondContact O-SG 3.19Å; R416-R420 VanDerWaalsContact CD-NH2 3.33Å; R416-R420 WeakPolarHBondContact O-CB 3.33Å; R416-R420 WeakPolarHBondContact O-CD 3.36Å; R416-R420 WeakPolarHBondContact O-CG 3.5Å; R416-R420 PolarHBondContact O-N 3.45Å
417D95.5Very high80.8Confident3 Ų339.8 Ų39.82%0.01626%0.257CS..THydrogen-bonded Turntrans-54.9-44.2177.3-69.9-30.6000113.9V391 I396 K397 D398 C419 R420 A421 L443V391-D417 HydrophobicContact CG1-CB 4.4Å; V391-D417 HydrophobicContact CG2-CB 3.98Å; I396-D417 WeakPolarHBondContact CA-OD2 3.38Å; K397-D417 PolarHBondContact N-OD2 3.43Å; D398-D417 WeakPolarHBondContact CB-OD1 3.24Å; D398-D417 WeakPolarHBondContact CB-OD2 3.28Å; D398-D417 PolarHBondContact N-OD1 3.45Å; D398-D417 PolarHBondContact N-OD2 3.24Å; D417-C419 VanDerWaalsContact C-N 3.3Å; D417-C419 PolarHBondContact O-N 3.47Å; D417-R420 PolarHBondContact O-N 3.33Å; D417-A421 PolarHBondContact O-N 3.2Å; D417-L443 HydrophobicContact CB-CD1 4Å; D417-L443 HydrophobicContact CB-CD2 3.96Å
418P94.7Very high81.8Confident30 Ų3043.6 Ų43.620%0.19526%0.256CS..THydrogen-bonded Turntrans-58.7-37.8-176.4-27.937.7000114.1D388 V389 V391 R416D388-P418 WeakPolarHBondContact CA-O 3.46Å; D388-P418 HydrophobicContact CB-CB 3.75Å; V389-P418 PolarHBondContact N-O 3.44Å; V389-P418 VanDerWaalsContact O-CB 3.31Å; V389-P418 WeakPolarHBondContact O-CB 3.37Å; V391-P418 HydrophobicContact CG2-CG 4.21Å; R416-P418 VanDerWaalsContact C-CD 3.47Å
419C95.5Very high83.1Confident3 Ų344.2 Ų44.22%0.0226%0.259CS..THydrogen-bonded Turntrans-83.2-20178.166.60000112.7H347 Q349 R351 Y379 D388 R416 D417 A421H347-C419 PolarHBondContact O-SG 3.37Å; Q349-C419 VanDerWaalsContact O-CB 3.23Å; Q349-C419 WeakPolarHBondContact O-CB 3.38Å; Q349-C419 PolarHBondContact O-SG 3.36Å; R351-C419 HydrophobicContact CG-CB 3.94Å; R351-C419 PolarHBondContact NE-O 3.46Å; R351-C419 PolarHBondContact NH2-O 2.65Å; Y379-C419 PolarHBondContact OH-O 2.97Å; D388-C419 WeakPolarHBondContact OD1-CA 3.39Å; D388-C419 WeakPolarHBondContact OD1-CB 3.33Å; R416-C419 PolarHBondContact O-N 2.88Å; R416-C419 PolarHBondContact O-SG 3.19Å; D417-C419 VanDerWaalsContact C-N 3.3Å; D417-C419 PolarHBondContact O-N 3.47Å; C419-A421 PolarHBondContact O-N 2.89Å
420R97.1Very high84.3Confident0 Ų047.2 Ų47.20%027%0.268CS..THydrogen-bonded Turntrans-88.89.6179.4-67.8169.8178.6-173.3-4.6114.1Y26 S29 F72 H347 D348 Y380 D398 R416 D417 L443Y26-R420 HydrophobicContact CD1-CB 4.26Å; Y26-R420 HydrophobicContact CD1-CG 4.41Å; Y26-R420 HydrophobicContact CE1-CB 4.01Å; Y26-R420 HydrophobicContact CE1-CG 4.09Å; Y26-R420 HydrophobicContact CE2-CG 4.26Å; S29-R420 VanDerWaalsContact CB-O 3.23Å; S29-R420 WeakPolarHBondContact CB-O 3.14Å; S29-R420 PolarHBondContact OG-O 2.87Å; F72-R420 VanDerWaalsContact CD2-NH1 3.33Å; H347-R420 HydrophobicContact CB-CG 4.38Å; H347-R420 PolarHBondContact CD2-NH2 3.43Å; H347-R420 PolarHBondContact O-NE 3.24Å; H347-R420 PolarHBondContact O-NH2 3.29Å; D348-R420 IonicContact OD1-NH2 3.33Å; D348-R420 PolarHBondContact OD1-NH2 2.68Å; Y380-R420 PolarHBondContact OH-O 3.2Å; D398-R420 IonicContact OD1-NH1 3.07Å; R416-R420 VanDerWaalsContact CD-NH2 3.33Å; R416-R420 WeakPolarHBondContact O-CB 3.33Å; R416-R420 WeakPolarHBondContact O-CD 3.36Å; R416-R420 WeakPolarHBondContact O-CG 3.5Å; R416-R420 PolarHBondContact O-N 3.45Å; D417-R420 PolarHBondContact O-N 3.33Å; R420-L443 HydrophobicContact CB-CD1 4.22Å
421A95.7Very high85.9Confident1 Ų142.1 Ų42.11%0.00824%0.244CC..PPolyproline II helixtrans-63.1156.5-175.700000114.7Y380 M386 V389 D417 C419Y380-A421 PolarHBondContact OH-O 2.93Å; M386-A421 HydrophobicContact CE-CB 3.83Å; M386-A421 WeakPolarHBondContact CE-O 3.41Å; V389-A421 HydrophobicContact CB-CB 3.71Å; V389-A421 HydrophobicContact CG2-CB 3.4Å; D417-A421 PolarHBondContact O-N 3.2Å; C419-A421 PolarHBondContact O-N 2.89Å
422P97Very high87.7Confident4 Ų441.4 Ų41.43%0.02624%0.238CC..PPolyproline II helixtrans-62.5145.1-177-20.131.8000114.6S29 F434 A441 L443 P444 M445S29-P422 WeakPolarHBondContact O-CA 3.35Å; P422-F434 HydrophobicContact CB-CB 4.45Å; P422-F434 HydrophobicContact CB-CD1 3.78Å; P422-F434 HydrophobicContact CB-CD2 3.84Å; P422-F434 HydrophobicContact CB-CE1 3.97Å; P422-F434 HydrophobicContact CB-CE2 4.04Å; P422-F434 HydrophobicContact CB-CG 3.73Å; P422-F434 HydrophobicContact CB-CZ 4.1Å; P422-F434 HydrophobicContact CG-CD1 4.32Å; P422-F434 HydrophobicContact CG-CE1 4.19Å; P422-F434 HydrophobicContact CG-CZ 4.47Å; P422-A441 HydrophobicContact CB-CB 4.28Å; P422-A441 HydrophobicContact CG-CB 3.61Å; P422-L443 HydrophobicContact CG-CB 4.49Å; P422-L443 WeakPolarHBondContact CG-O 3.48Å; P422-P444 WeakPolarHBondContact CD-O 3.31Å; P422-M445 HydrophobicContact CB-CG 3.99Å; P422-M445 HydrophobicContact CG-CG 3.97Å
423L96.4Very high89.5Confident0 Ų037 Ų370%021%0.211CC..PPolyproline II helixtrans-79.2130.6176.6-167.866.6000111.6S29 F30 Y380 L384 M386 W425 V454S29-L423 PolarHBondContact O-N 3.04Å; F30-L423 HydrophobicContact CD2-CD2 4.13Å; F30-L423 HydrophobicContact CE2-CD2 3.98Å; Y380-L423 HydrophobicContact CD2-CB 4.01Å; Y380-L423 HydrophobicContact CD2-CD1 3.93Å; Y380-L423 HydrophobicContact CD2-CD2 4.29Å; Y380-L423 HydrophobicContact CD2-CG 4.3Å; Y380-L423 HydrophobicContact CE2-CB 3.99Å; Y380-L423 HydrophobicContact CE2-CD1 4.36Å; L384-L423 HydrophobicContact CD1-CD1 3.45Å; L384-L423 VanDerWaalsContact CD1-CD1 3.45Å; L384-L423 HydrophobicContact CD1-CG 4.33Å; M386-L423 HydrophobicContact SD-CD1 4.34Å; L423-W425 HydrophobicContact CD2-CH2 4.05Å; L423-W425 HydrophobicContact CD2-CZ2 3.61Å; L423-W425 PolarHBondContact O-N 2.84Å; L423-V454 HydrophobicContact CD2-CG2 4.49Å
424A95.9Very high91.5Very high14 Ų1433 Ų3312%0.11619%0.192CC..  trans-83.2110174.200000111.5A432 I451 S453 V454A424-A432 HydrophobicContact CB-CB 3.69Å; A424-I451 HydrophobicContact CB-CG2 3.66Å; A424-S453 VanDerWaalsContact O-CA 3.28Å; A424-S453 WeakPolarHBondContact O-CA 3.47Å; A424-V454 PolarHBondContact O-N 3.45Å
425W96.9Very high92.9Very high14 Ų1430.5 Ų30.55%0.05318%0.176CC..  trans-82.9-41.9179.9-75.599.4000113.3F30 K31 K47 Y50 L423 A432 V454 E455F30-W425 HydrophobicContact CD1-CZ2 4.2Å; F30-W425 HydrophobicContact CD2-CZ2 4.24Å; F30-W425 HydrophobicContact CE1-CH2 4.11Å; F30-W425 AromaticContact CE1-CZ2 3.68Å; F30-W425 HydrophobicContact CE1-CZ2 3.68Å; F30-W425 HydrophobicContact CE2-CH2 4.03Å; F30-W425 AromaticContact CE2-CZ2 3.72Å; F30-W425 HydrophobicContact CE2-CZ2 3.72Å; F30-W425 HydrophobicContact CG-CZ2 4.46Å; F30-W425 AromaticContact CZ-CH2 3.55Å; F30-W425 HydrophobicContact CZ-CH2 3.55Å; F30-W425 AromaticContact CZ-CZ2 3.41Å; F30-W425 HydrophobicContact CZ-CZ2 3.41Å; F30-W425 VanDerWaalsContact CZ-CZ2 3.41Å; F30-W425 PolarHBondContact O-NE1 2.73Å; K31-W425 HydrophobicContact CD-CG 4.32Å; K47-W425 HydrophobicContact CB-CH2 3.73Å; K47-W425 HydrophobicContact CB-CZ2 4.15Å; K47-W425 HydrophobicContact CB-CZ3 4.31Å; K47-W425 HydrophobicContact CD-CD2 4.16Å; K47-W425 HydrophobicContact CD-CE3 3.91Å; K47-W425 HydrophobicContact CD-CH2 3.83Å; K47-W425 HydrophobicContact CD-CZ2 4.06Å; K47-W425 HydrophobicContact CD-CZ3 3.74Å; K47-W425 HydrophobicContact CG-CE3 4.46Å; K47-W425 HydrophobicContact CG-CH2 3.51Å; K47-W425 HydrophobicContact CG-CZ2 3.56Å; K47-W425 HydrophobicContact CG-CZ3 3.98Å; Y50-W425 AromaticContact CD1-CH2 3.9Å; Y50-W425 HydrophobicContact CD1-CH2 3.9Å; Y50-W425 AromaticContact CD1-CZ3 3.99Å; Y50-W425 HydrophobicContact CD1-CZ3 3.99Å; Y50-W425 HydrophobicContact CD2-CZ3 4.43Å; Y50-W425 HydrophobicContact CE1-CH2 4.29Å; Y50-W425 HydrophobicContact CE1-CZ3 4.39Å; Y50-W425 HydrophobicContact CG-CH2 4.33Å; Y50-W425 AromaticContact CG-CZ3 3.99Å; Y50-W425 HydrophobicContact CG-CZ3 3.99Å; L423-W425 HydrophobicContact CD2-CH2 4.05Å; L423-W425 HydrophobicContact CD2-CZ2 3.61Å; L423-W425 PolarHBondContact O-N 2.84Å; W425-A432 PolarHBondContact N-O 3.28Å; W425-V454 HydrophobicContact CD2-CG2 4.46Å; W425-V454 HydrophobicContact CE3-CB 3.99Å; W425-V454 HydrophobicContact CE3-CG1 4.15Å; W425-V454 HydrophobicContact CE3-CG2 3.79Å; W425-V454 HydrophobicContact CZ3-CB 4.38Å; W425-V454 HydrophobicContact CZ3-CG1 4.17Å; W425-V454 HydrophobicContact CZ3-CG2 3.97Å; W425-V454 PolarHBondContact O-N 2.74Å; W425-E455 WeakPolarHBondContact O-CB 3.25Å; W425-E455 PolarHBondContact O-N 2.83Å
426N93.6Very high93.4Very high32 Ų3233.5 Ų33.517%0.17119%0.192CC..  trans-142.3169.8179.769.754.9000111.5M428 D429 A432 E455N426-M428 PolarHBondContact OD1-N 2.98Å; N426-D429 PolarHBondContact ND2-OD2 3.1Å; N426-D429 WeakPolarHBondContact OD1-CB 3.23Å; N426-D429 PolarHBondContact OD1-N 3.4Å; N426-A432 PolarHBondContact N-O 3.15Å; N426-A432 CarbonylContact O-C 3.55Å; N426-A432 VanDerWaalsContact O-C 3.29Å; N426-A432 WeakPolarHBondContact O-CA 3.29Å; N426-A432 WeakPolarHBondContact O-CB 3.46Å; N426-E455 HydrophobicContact CB-CB 4Å; N426-E455 HydrophobicContact CB-CG 4.41Å
427S87.3Confident93.5Very high27 Ų2733.1 Ų33.119%0.18919%0.193CC..SBendtrans-100.5-8.3-176.4-36.30000112.6Y448 S453 E455S427-Y448 VanDerWaalsContact O-CE2 3.28Å; S427-Y448 WeakPolarHBondContact O-CE2 3.23Å; S427-Y448 PolarHBondContact O-OH 3.33Å; S427-S453 PolarHBondContact OG-OG 3.14Å; S427-E455 PolarHBondContact OG-OE2 3.24Å
428M81.4Confident93.4Very high156 Ų15639.5 Ų39.577%0.76824%0.235SC*.SBendtrans-100.3-32.4-166.6-63-59.3-63.800113N426N426-M428 PolarHBondContact OD1-N 2.98Å
429D85.7Confident93.3Very high93 Ų9347.1 Ų47.150%0.49727%0.268SS..SBendtrans-88155.3-176.5-58.3-21.1000110.9N426 A432N426-D429 PolarHBondContact ND2-OD2 3.1Å; N426-D429 WeakPolarHBondContact OD1-CB 3.23Å; N426-D429 PolarHBondContact OD1-N 3.4Å; D429-A432 WeakPolarHBondContact O-CA 3.47Å; D429-A432 PolarHBondContact O-N 2.93Å
430D84.9Confident93.3Very high147 Ų14747.8 Ų47.879%0.78628%0.275SS*.G310 helixtrans-54.5146.8167.1-68.8-33.4000110.4A432 G433D430-A432 PolarHBondContact O-N 2.82Å; D430-G433 PolarHBondContact O-N 3.16Å
431C91.1Very high93.2Very high37 Ų3748.8 Ų48.825%0.2528%0.284CS..G310 helixtrans4930.5-171.9-61.90000113.4G433 F434 T435 M445C431-G433 PolarHBondContact O-N 2.98Å; C431-G433 VanDerWaalsContact O-N 3.14Å; C431-F434 VanDerWaalsContact O-CB 3.24Å; C431-F434 WeakPolarHBondContact O-CB 3.45Å; C431-F434 PolarHBondContact O-N 2.96Å; C431-T435 HydrophobicContact CB-CG2 3.76Å; C431-M445 VanDerWaalsContact C-CE 3.41Å; C431-M445 VanDerWaalsContact C-SD 3.59Å; C431-M445 HydrophobicContact CB-SD 3.77Å; C431-M445 WeakPolarHBondContact O-CE 3.5Å
432A93.8Very high93.2Very high4 Ų449.4 Ų49.43%0.03329%0.286CS..G310 helixtrans53.834.4176.200000114A424 W425 N426 D429 D430 F434 M445 I451A424-A432 HydrophobicContact CB-CB 3.69Å; W425-A432 PolarHBondContact N-O 3.28Å; N426-A432 PolarHBondContact N-O 3.15Å; N426-A432 CarbonylContact O-C 3.55Å; N426-A432 VanDerWaalsContact O-C 3.29Å; N426-A432 WeakPolarHBondContact O-CA 3.29Å; N426-A432 WeakPolarHBondContact O-CB 3.46Å; D429-A432 WeakPolarHBondContact O-CA 3.47Å; D429-A432 PolarHBondContact O-N 2.93Å; D430-A432 PolarHBondContact O-N 2.82Å; A432-F434 PolarHBondContact O-N 2.83Å; A432-M445 HydrophobicContact CB-CE 3.46Å; A432-M445 VanDerWaalsContact CB-CE 3.46Å; A432-I451 HydrophobicContact CB-CD1 3.99Å
433G94.8Very high93.2Very high8 Ų849.4 Ų49.48%0.08229%0.285CS..G310 helixtrans72.28.8-178.200000114.7K31 D430 C431K31-G433 WeakPolarHBondContact CD-O 3.32Å; K31-G433 WeakPolarHBondContact CE-O 3.25Å; K31-G433 PolarHBondContact NZ-O 3.22Å; D430-G433 PolarHBondContact O-N 3.16Å; C431-G433 PolarHBondContact O-N 2.98Å; C431-G433 VanDerWaalsContact O-N 3.14Å
434F96.8Very high93.1Very high0 Ų051.1 Ų51.10%030%0.297CS..SBendtrans-70.6-52.4174.8170.3-106.2000111.7R28 S29 K31 D32 G37 P422 C431 A432 A441R28-F434 WeakPolarHBondContact O-CZ 3.38Å; S29-F434 VanDerWaalsContact C-CE2 3.46Å; S29-F434 WeakPolarHBondContact O-CE2 3.43Å; K31-F434 PolarHBondContact NZ-O 2.83Å; D32-F434 HydrophobicContact CB-CE1 4.43Å; D32-F434 HydrophobicContact CB-CZ 4.25Å; D32-F434 PolarHBondContact N-O 3.14Å; G37-F434 VanDerWaalsContact O-CE1 3.31Å; G37-F434 WeakPolarHBondContact O-CE1 3.46Å; P422-F434 HydrophobicContact CB-CB 4.45Å; P422-F434 HydrophobicContact CB-CD1 3.78Å; P422-F434 HydrophobicContact CB-CD2 3.84Å; P422-F434 HydrophobicContact CB-CE1 3.97Å; P422-F434 HydrophobicContact CB-CE2 4.04Å; P422-F434 HydrophobicContact CB-CG 3.73Å; P422-F434 HydrophobicContact CB-CZ 4.1Å; P422-F434 HydrophobicContact CG-CD1 4.32Å; P422-F434 HydrophobicContact CG-CE1 4.19Å; P422-F434 HydrophobicContact CG-CZ 4.47Å; C431-F434 VanDerWaalsContact O-CB 3.24Å; C431-F434 WeakPolarHBondContact O-CB 3.45Å; C431-F434 PolarHBondContact O-N 2.96Å; A432-F434 PolarHBondContact O-N 2.83Å; F434-A441 HydrophobicContact CD1-CB 3.56Å; F434-A441 HydrophobicContact CE1-CB 3.56Å
435T97.3Very high92.8Very high8 Ų852.6 Ų52.65%0.04930%0.302CS..  trans-141.7154.3-176.7-177.90000111.4D32 C431 C437 A441D32-T435 WeakPolarHBondContact OD2-CB 3.44Å; D32-T435 PolarHBondContact OD2-OG1 2.66Å; C431-T435 HydrophobicContact CB-CG2 3.76Å; T435-C437 HydrophobicContact CG2-CB 4.08Å; T435-C437 WeakPolarHBondContact OG1-CB 3.35Å; T435-C437 PolarHBondContact OG1-N 2.73Å; T435-A441 HydrophobicContact CG2-CB 4.37Å
436S95.5Very high92.2Very high97 Ų9753.8 Ų53.868%0.67831%0.31SS*.  trans-98.26.616655.30000113.1P438S436-P438 WeakPolarHBondContact O-CD 3.41Å
437C96.4Very high91.5Very high18 Ų1860.9 Ų60.912%0.12234%0.335CS..  trans-59.8125.4180-170.70000111G35 T435 E439 G440G35-C437 WeakPolarHBondContact O-CA 3.43Å; G35-C437 WeakPolarHBondContact O-CB 3.38Å; G35-C437 PolarHBondContact O-SG 3.12Å; G35-C437 VanDerWaalsContact O-SG 3.35Å; T435-C437 HydrophobicContact CG2-CB 4.08Å; T435-C437 WeakPolarHBondContact OG1-CB 3.35Å; T435-C437 PolarHBondContact OG1-N 2.73Å; C437-E439 PolarHBondContact O-N 2.77Å; C437-G440 PolarHBondContact O-N 2.86Å
438P93.3Very high91Very high136 Ų13667.1 Ų67.188%0.88336%0.356SS*.THydrogen-bonded Turntrans-60.7-28.2178.2-25.234.9000114.1S436 G440S436-P438 WeakPolarHBondContact O-CD 3.41Å; P438-G440 VanDerWaalsContact C-N 3.26Å
439E93.9Very high90.6Very high190 Ų19064.6 Ų64.689%0.88835%0.353SS*.THydrogen-bonded Turntrans-80.8-8.4176.9-63.9177.6-172.200112.6C437C437-E439 PolarHBondContact O-N 2.77Å
440G93.7Very high90.3Very high17 Ų1764.8 Ų64.818%0.17535%0.354CS..  trans88.3-166-179.500000113.8G37 C437 P438G37-G440 WeakPolarHBondContact CA-O 3.5Å; C437-G440 PolarHBondContact O-N 2.86Å; P438-G440 VanDerWaalsContact C-N 3.26Å
441A96.2Very high89.9Confident22 Ų2259.2 Ų59.218%0.18232%0.324CS..  trans-76.2153.2-179.100000112.4P422 F434 T435 L443 M445P422-A441 HydrophobicContact CB-CB 4.28Å; P422-A441 HydrophobicContact CG-CB 3.61Å; F434-A441 HydrophobicContact CD1-CB 3.56Å; F434-A441 HydrophobicContact CE1-CB 3.56Å; T435-A441 HydrophobicContact CG2-CB 4.37Å; A441-L443 WeakPolarHBondContact CB-O 3.15Å; A441-L443 PolarHBondContact O-N 3.18Å; A441-M445 HydrophobicContact CB-CG 4.25Å; A441-M445 HydrophobicContact CB-SD 4.37Å
442W96.4Very high89.6Confident13 Ų1360.3 Ų60.35%0.04933%0.327CS..SBendtrans-63.2-24.1-178.478.6-75.3000114.2Y26 R28 S29 G37 I38 F72 K397Y26-W442 HydrophobicContact CD1-CZ2 4.41Å; Y26-W442 HydrophobicContact CE1-CH2 4.02Å; Y26-W442 AromaticContact CE1-CZ2 3.75Å; Y26-W442 HydrophobicContact CE1-CZ2 3.75Å; R28-W442 HydrophobicContact CB-CZ2 3.94Å; R28-W442 VanDerWaalsContact O-CD1 3.22Å; R28-W442 PolarHBondContact O-NE1 3.2Å; S29-W442 VanDerWaalsContact OG-CZ2 3.31Å; S29-W442 WeakPolarHBondContact OG-CZ2 3.47Å; S29-W442 PolarHBondContact OG-NE1 2.9Å; G37-W442 WeakPolarHBondContact O-CB 3.46Å; G37-W442 PolarHBondContact O-N 2.81Å; I38-W442 HydrophobicContact CD1-CB 4.34Å; I38-W442 HydrophobicContact CG1-CB 3.58Å; I38-W442 HydrophobicContact CG1-CG 4.01Å; F72-W442 HydrophobicContact CD1-CZ3 4.25Å; F72-W442 AromaticContact CE1-CZ3 3.88Å; F72-W442 HydrophobicContact CE1-CZ3 3.88Å; F72-W442 HydrophobicContact CE2-CH2 4.39Å; F72-W442 HydrophobicContact CE2-CZ3 4.31Å; F72-W442 HydrophobicContact CZ-CH2 4.41Å; F72-W442 AromaticContact CZ-CZ3 3.89Å; F72-W442 HydrophobicContact CZ-CZ3 3.89Å; K397-W442 HydrophobicContact CD-CE3 3.95Å; K397-W442 HydrophobicContact CD-CZ3 4.35Å; K397-W442 WeakPolarHBondContact CD-O 3.38Å; K397-W442 WeakPolarHBondContact CE-O 3.3Å; K397-W442 PolarHBondContact NZ-O 3.17Å
443L96.1Very high89.6Confident4 Ų460.1 Ų60.12%0.02133%0.326CS..SBendtrans-125.1155.5169.3-82.5-178.9000109.9K397 D417 R420 P422 A441 M445K397-L443 HydrophobicContact CB-CD2 4.48Å; K397-L443 HydrophobicContact CD-CD2 4.3Å; K397-L443 HydrophobicContact CG-CD2 4.37Å; D417-L443 HydrophobicContact CB-CD1 4Å; D417-L443 HydrophobicContact CB-CD2 3.96Å; R420-L443 HydrophobicContact CB-CD1 4.22Å; P422-L443 HydrophobicContact CG-CB 4.49Å; P422-L443 WeakPolarHBondContact CG-O 3.48Å; A441-L443 WeakPolarHBondContact CB-O 3.15Å; A441-L443 PolarHBondContact O-N 3.18Å; L443-M445 PolarHBondContact O-N 3.1Å
444P94Very high89.7Confident36 Ų3660.1 Ų60.123%0.23432%0.324CS..PPolyproline II helixtrans-52.7140.8172.3-25.434.7000111.8V389 V391 A395 P422V389-P444 HydrophobicContact CG1-CB 4.11Å; V389-P444 WeakPolarHBondContact CG1-O 3.45Å; V391-P444 HydrophobicContact CG1-CG 4.29Å; A395-P444 HydrophobicContact CB-CG 3.94Å; P422-P444 WeakPolarHBondContact CD-O 3.31Å
445M90.3Very high89.7Confident45 Ų4564.1 Ų64.122%0.22234%0.342CS..PPolyproline II helixtrans-92.6163.9173.6-74.8-179.530.200112V389 P422 C431 A432 A441 L443 I451V389-M445 WeakPolarHBondContact CG1-O 3.19Å; P422-M445 HydrophobicContact CB-CG 3.99Å; P422-M445 HydrophobicContact CG-CG 3.97Å; C431-M445 VanDerWaalsContact C-CE 3.41Å; C431-M445 VanDerWaalsContact C-SD 3.59Å; C431-M445 HydrophobicContact CB-SD 3.77Å; C431-M445 WeakPolarHBondContact O-CE 3.5Å; A432-M445 HydrophobicContact CB-CE 3.46Å; A432-M445 VanDerWaalsContact CB-CE 3.46Å; A441-M445 HydrophobicContact CB-CG 4.25Å; A441-M445 HydrophobicContact CB-SD 4.37Å; L443-M445 PolarHBondContact O-N 3.1Å; M445-I451 HydrophobicContact CE-CD1 4.23Å
446T84.1Confident89.6Confident39 Ų3965.5 Ų65.524%0.23936%0.355CS..PPolyproline II helixtrans-56.8139.9167.4-58.40000109.8V389 Y448 D450 I451V389-T446 WeakPolarHBondContact CG2-OG1 3.37Å; T446-Y448 PolarHBondContact O-N 3.47Å; T446-D450 HydrophobicContact CG2-CB 3.78Å; T446-I451 HydrophobicContact CG2-CG1 4.42Å
447R79.2Confident89.6Confident181 Ų18161.4 Ų61.468%0.68333%0.325SS*.PPolyproline II helixtrans-55.5139.8176.1-67.3-178.4179.1-174.3-0.3110.3S449 D450 I451R447-S449 PolarHBondContact O-N 2.99Å; R447-D450 CarbonylContact O-C 3.35Å; R447-D450 WeakPolarHBondContact O-CA 3.46Å; R447-D450 PolarHBondContact O-N 2.69Å; R447-I451 WeakPolarHBondContact O-CG1 3.29Å; R447-I451 PolarHBondContact O-N 2.94Å; R447-I451 VanDerWaalsContact O-N 3.16Å
448Y75.5Confident89.6Confident159 Ų15965.8 Ų65.862%0.62434%0.339SS*.G310 helixtrans-52.3-37-176.1-167.8-94.2000113.9S427 T446 D450 I451S427-Y448 VanDerWaalsContact O-CE2 3.28Å; S427-Y448 WeakPolarHBondContact O-CE2 3.23Å; S427-Y448 PolarHBondContact O-OH 3.33Å; T446-Y448 PolarHBondContact O-N 3.47Å; Y448-D450 PolarHBondContact O-N 3.41Å; Y448-I451 HydrophobicContact CD2-CD1 3.96Å; Y448-I451 HydrophobicContact CG-CD1 4.49Å; Y448-I451 PolarHBondContact O-N 2.64Å
449S74.5Confident89.6Confident102 Ų10263.7 Ų63.771%0.71333%0.328SS*.G310 helixtrans-63.2-25.6175.851.10000114.9R447R447-S449 PolarHBondContact O-N 2.99Å
450D78.7Confident89.7Confident97 Ų9757.6 Ų57.652%0.51930%0.303SS..G310 helixtrans-109.23.8-175.6-58.2-61.9000111.8T446 R447 Y448 L452T446-D450 HydrophobicContact CG2-CB 3.78Å; R447-D450 CarbonylContact O-C 3.35Å; R447-D450 WeakPolarHBondContact O-CA 3.46Å; R447-D450 PolarHBondContact O-N 2.69Å; Y448-D450 PolarHBondContact O-N 3.41Å; D450-L452 PolarHBondContact O-N 3.28Å
451I76.8Confident89.6Confident30 Ų3060.8 Ų60.815%0.15432%0.321CS..  trans-64.9127.2-178.6-76.8179.4000110.3A424 A432 M445 T446 R447 Y448A424-I451 HydrophobicContact CB-CG2 3.66Å; A432-I451 HydrophobicContact CB-CD1 3.99Å; M445-I451 HydrophobicContact CE-CD1 4.23Å; T446-I451 HydrophobicContact CG2-CG1 4.42Å; R447-I451 WeakPolarHBondContact O-CG1 3.29Å; R447-I451 PolarHBondContact O-N 2.94Å; R447-I451 VanDerWaalsContact O-N 3.16Å; Y448-I451 HydrophobicContact CD2-CD1 3.96Å; Y448-I451 HydrophobicContact CG-CD1 4.49Å; Y448-I451 PolarHBondContact O-N 2.64Å
452L84.3Confident89.3Confident60 Ų6063 Ų6331%0.31434%0.335SS..  trans-107.260.6175.7-70.4-178.7000109.9L384 D450 Q457 Y464L384-L452 VanDerWaalsContact O-CD1 3.31Å; L384-L452 WeakPolarHBondContact O-CD1 3.21Å; D450-L452 PolarHBondContact O-N 3.28Å; L452-Q457 PolarHBondContact O-NE2 3.47Å; L452-Y464 HydrophobicContact CD1-CD2 4.26Å; L452-Y464 HydrophobicContact CD1-CE2 4.12Å; L452-Y464 HydrophobicContact CD2-CE2 4.49Å
453S94.4Very high89.2Confident1 Ų163 Ų631%0.00734%0.337CS..  trans-63.4150.5-170.772.60000113.7A424 S427 E455 A456 Q457A424-S453 VanDerWaalsContact O-CA 3.28Å; A424-S453 WeakPolarHBondContact O-CA 3.47Å; S427-S453 PolarHBondContact OG-OG 3.14Å; S453-E455 VanDerWaalsContact C-N 3.34Å; S453-E455 PolarHBondContact O-N 2.91Å; S453-A456 VanDerWaalsContact OG-CB 3.28Å; S453-A456 WeakPolarHBondContact OG-CB 3.13Å; S453-A456 PolarHBondContact OG-N 2.75Å; S453-Q457 WeakPolarHBondContact O-CB 3.42Å; S453-Q457 WeakPolarHBondContact O-CG 3.41Å; S453-Q457 PolarHBondContact O-N 3.35Å
454V97.3Very high89.2Confident7 Ų765.3 Ų65.34%0.04235%0.346CS..Hα-helixtrans-57.7-47.3177175.40000111Y50 L384 L423 A424 W425 Q457 R458 L465Y50-V454 HydrophobicContact CD2-CG1 3.8Å; Y50-V454 HydrophobicContact CE2-CG1 3.48Å; Y50-V454 VanDerWaalsContact CE2-CG1 3.48Å; L384-V454 HydrophobicContact CD1-CG2 3.81Å; L384-V454 HydrophobicContact CD2-CG2 4.18Å; L423-V454 HydrophobicContact CD2-CG2 4.49Å; A424-V454 PolarHBondContact O-N 3.45Å; W425-V454 HydrophobicContact CD2-CG2 4.46Å; W425-V454 HydrophobicContact CE3-CB 3.99Å; W425-V454 HydrophobicContact CE3-CG1 4.15Å; W425-V454 HydrophobicContact CE3-CG2 3.79Å; W425-V454 HydrophobicContact CZ3-CB 4.38Å; W425-V454 HydrophobicContact CZ3-CG1 4.17Å; W425-V454 HydrophobicContact CZ3-CG2 3.97Å; W425-V454 PolarHBondContact O-N 2.74Å; V454-Q457 PolarHBondContact O-N 3.29Å; V454-R458 WeakPolarHBondContact O-CB 3.33Å; V454-R458 PolarHBondContact O-N 3.45Å; V454-L465 HydrophobicContact CG1-CD2 4.21Å
455E95.9Very high89.4Confident84 Ų8463.6 Ų63.639%0.39334%0.335SS..Hα-helixtrans-58-53.7179.5175.1-86.2140.800112.7W425 N426 S427 S453 Q457 R458 S459W425-E455 WeakPolarHBondContact O-CB 3.25Å; W425-E455 PolarHBondContact O-N 2.83Å; N426-E455 HydrophobicContact CB-CB 4Å; N426-E455 HydrophobicContact CB-CG 4.41Å; S427-E455 PolarHBondContact OG-OE2 3.24Å; S453-E455 VanDerWaalsContact C-N 3.34Å; S453-E455 PolarHBondContact O-N 2.91Å; E455-Q457 PolarHBondContact O-N 3.16Å; E455-R458 PolarHBondContact O-N 3.43Å; E455-S459 PolarHBondContact O-N 3.03Å; E455-S459 PolarHBondContact O-OG 3.42Å
456A94.7Very high89.7Confident37 Ų3763 Ų6331%0.30633%0.333SS..Hα-helixtrans-64.2-40.8-178.600000112S453 T460S453-A456 VanDerWaalsContact OG-CB 3.28Å; S453-A456 WeakPolarHBondContact OG-CB 3.13Å; S453-A456 PolarHBondContact OG-N 2.75Å; A456-T460 WeakPolarHBondContact O-CB 3.49Å; A456-T460 PolarHBondContact O-N 2.97Å; A456-T460 PolarHBondContact O-OG1 2.81Å
457Q96.4Very high90.3Very high11 Ų1161.6 Ų61.65%0.05132%0.323CS..Hα-helixtrans-70.4-34.3178.5-72.5-157.562.900112.9L384 L452 S453 V454 E455 S459 T460 S463 Y464 L465 N466L384-Q457 PolarHBondContact O-NE2 3.39Å; L452-Q457 PolarHBondContact O-NE2 3.47Å; S453-Q457 WeakPolarHBondContact O-CB 3.42Å; S453-Q457 WeakPolarHBondContact O-CG 3.41Å; S453-Q457 PolarHBondContact O-N 3.35Å; V454-Q457 PolarHBondContact O-N 3.29Å; E455-Q457 PolarHBondContact O-N 3.16Å; Q457-S459 VanDerWaalsContact C-N 3.29Å; Q457-S459 PolarHBondContact O-N 3.13Å; Q457-T460 PolarHBondContact O-N 2.97Å; Q457-T460 VanDerWaalsContact O-O 3.13Å; Q457-S463 WeakPolarHBondContact O-CB 3.4Å; Q457-S463 PolarHBondContact O-OG 3.02Å; Q457-Y464 VanDerWaalsContact OE1-N 3.07Å; Q457-L465 HydrophobicContact CB-CB 3.71Å; Q457-L465 HydrophobicContact CB-CD2 4.03Å; Q457-N466 PolarHBondContact O-ND2 3.39Å
458R96Very high91.2Very high111 Ų11153 Ų5342%0.41929%0.29SS..Hα-helixtrans-62.2-39.3178.1-175.6172.3-175.5177.71111.3W53 V454 E455 T460 L465 N466W53-R458 VanDerWaalsContact CD1-NH2 3.26Å; W53-R458 HydrophobicContact CH2-CB 4.48Å; W53-R458 HydrophobicContact CH2-CG 3.97Å; W53-R458 HydrophobicContact CZ2-CG 3.73Å; W53-R458 HydrophobicContact CZ3-CG 4.5Å; V454-R458 WeakPolarHBondContact O-CB 3.33Å; V454-R458 PolarHBondContact O-N 3.45Å; E455-R458 PolarHBondContact O-N 3.43Å; R458-T460 VanDerWaalsContact C-N 3.32Å; R458-L465 HydrophobicContact CB-CD2 4.16Å; R458-N466 PolarHBondContact O-ND2 3.21Å
459S93.6Very high92.3Very high92 Ų9247.3 Ų47.364%0.64327%0.269SS*.Hα-helixtrans-78.4-12.3177.9-59.30000114.1E455 Q457 P461E455-S459 PolarHBondContact O-N 3.03Å; E455-S459 PolarHBondContact O-OG 3.42Å; Q457-S459 VanDerWaalsContact C-N 3.29Å; Q457-S459 PolarHBondContact O-N 3.13Å; S459-P461 WeakPolarHBondContact O-CD 3.32Å
460T94.8Very high93.3Very high62 Ų6243.5 Ų43.538%0.3824%0.244SC..  trans-104.6108.7-176-60.10000111.4A456 Q457 R458 S462 S463 N466A456-T460 WeakPolarHBondContact O-CB 3.49Å; A456-T460 PolarHBondContact O-N 2.97Å; A456-T460 PolarHBondContact O-OG1 2.81Å; Q457-T460 PolarHBondContact O-N 2.97Å; Q457-T460 VanDerWaalsContact O-O 3.13Å; R458-T460 VanDerWaalsContact C-N 3.32Å; T460-S462 VanDerWaalsContact C-N 3.26Å; T460-S462 PolarHBondContact O-N 3.04Å; T460-S462 VanDerWaalsContact O-N 3.13Å; T460-S463 VanDerWaalsContact O-CB 3.23Å; T460-S463 WeakPolarHBondContact O-CB 3.3Å; T460-S463 PolarHBondContact O-N 2.71Å; T460-S463 VanDerWaalsContact O-N 3.1Å; T460-S463 PolarHBondContact O-OG 3.11Å; T460-N466 PolarHBondContact O-ND2 3.26Å
461P91.8Very high94.3Very high83 Ų8338.9 Ų38.954%0.53922%0.219SC..THydrogen-bonded Turntrans-61.8-25.8-173.4-27.236000115.8S459 R546S459-P461 WeakPolarHBondContact O-CD 3.32Å; P461-R546 PolarHBondContact O-NH2 2.98Å
462S91.2Very high95.3Very high70 Ų7038.1 Ų38.149%0.4922%0.216SC..THydrogen-bonded Turntrans-91.41.2-179.156.50000113.9K363 T460K363-S462 WeakPolarHBondContact CE-O 3.43Å; K363-S462 PolarHBondContact NZ-O 3.19Å; T460-S462 VanDerWaalsContact C-N 3.26Å; T460-S462 PolarHBondContact O-N 3.04Å; T460-S462 VanDerWaalsContact O-N 3.13Å
463S94.7Very high95.8Very high12 Ų1240.7 Ų40.78%0.08423%0.226CC..SBendtrans-64.6164.8-176.670.40000113.1Q457 T460 L465 N466 H467Q457-S463 WeakPolarHBondContact O-CB 3.4Å; Q457-S463 PolarHBondContact O-OG 3.02Å; T460-S463 VanDerWaalsContact O-CB 3.23Å; T460-S463 WeakPolarHBondContact O-CB 3.3Å; T460-S463 PolarHBondContact O-N 2.71Å; T460-S463 VanDerWaalsContact O-N 3.1Å; T460-S463 PolarHBondContact O-OG 3.11Å; S463-L465 VanDerWaalsContact C-N 3.3Å; S463-N466 PolarHBondContact OG-N 2.93Å; S463-N466 VanDerWaalsContact OG-N 3.07Å; S463-N466 PolarHBondContact OG-ND2 2.86Å; S463-H467 WeakPolarHBondContact O-CB 3.49Å; S463-H467 PolarHBondContact O-N 2.9Å
464Y95.6Very high95.9Very high52 Ų5241.4 Ų41.420%0.20423%0.229CC..Hα-helixtrans-64.1-40.2174-54.4-62.7000110.7S359 T362 K363 E383 L384 L452 Q457 H467 F468S359-Y464 WeakPolarHBondContact O-CE1 2.72Å; S359-Y464 VanDerWaalsContact O-CZ 3.26Å; S359-Y464 PolarHBondContact O-OH 3.29Å; T362-Y464 HydrophobicContact CG2-CD1 4.09Å; T362-Y464 HydrophobicContact CG2-CG 4.14Å; K363-Y464 HydrophobicContact CD-CD1 4.41Å; K363-Y464 HydrophobicContact CG-CD1 3.73Å; K363-Y464 HydrophobicContact CG-CE1 4.14Å; E383-Y464 CarbonylContact O-C 3.55Å; E383-Y464 WeakPolarHBondContact O-CB 3.43Å; L384-Y464 VanDerWaalsContact O-CD2 3.28Å; L384-Y464 WeakPolarHBondContact O-CD2 3.45Å; L452-Y464 HydrophobicContact CD1-CD2 4.26Å; L452-Y464 HydrophobicContact CD1-CE2 4.12Å; L452-Y464 HydrophobicContact CD2-CE2 4.49Å; Q457-Y464 VanDerWaalsContact OE1-N 3.07Å; Y464-H467 WeakPolarHBondContact O-CB 3.48Å; Y464-H467 PolarHBondContact O-N 3.12Å; Y464-F468 WeakPolarHBondContact O-CB 3.42Å; Y464-F468 PolarHBondContact O-N 2.91Å
465L97.6Very high95.9Very high0 Ų041.5 Ų41.50%023%0.229CC..Hα-helixtrans-60.8-48.8177.4-173.761.1000112.8Y50 W53 L54 E383 L384 V454 Q457 R458 S463 H467 F468 K469Y50-L465 HydrophobicContact CE2-CD1 4.11Å; Y50-L465 HydrophobicContact CE2-CD2 4.28Å; Y50-L465 VanDerWaalsContact OH-CD1 3.27Å; Y50-L465 WeakPolarHBondContact OH-CD1 3.43Å; W53-L465 HydrophobicContact CH2-CD2 4.06Å; W53-L465 HydrophobicContact CH2-CG 3.97Å; W53-L465 HydrophobicContact CZ3-CD1 4.13Å; W53-L465 HydrophobicContact CZ3-CD2 3.86Å; W53-L465 HydrophobicContact CZ3-CG 3.81Å; L54-L465 HydrophobicContact CD2-CD1 3.77Å; E383-L465 HydrophobicContact CB-CD1 4.5Å; E383-L465 HydrophobicContact CG-CD1 3.72Å; E383-L465 PolarHBondContact O-N 2.94Å; L384-L465 HydrophobicContact CD2-CB 4.01Å; L384-L465 HydrophobicContact CD2-CD1 3.87Å; L384-L465 HydrophobicContact CD2-CD2 4.06Å; L384-L465 HydrophobicContact CD2-CG 4.2Å; V454-L465 HydrophobicContact CG1-CD2 4.21Å; Q457-L465 HydrophobicContact CB-CB 3.71Å; Q457-L465 HydrophobicContact CB-CD2 4.03Å; R458-L465 HydrophobicContact CB-CD2 4.16Å; S463-L465 VanDerWaalsContact C-N 3.3Å; L465-H467 VanDerWaalsContact C-N 3.31Å; L465-H467 PolarHBondContact O-N 2.89Å; L465-F468 WeakPolarHBondContact O-CB 3.44Å; L465-F468 PolarHBondContact O-N 2.84Å; L465-K469 PolarHBondContact O-N 3.38Å
466N96.9Very high95.8Very high34 Ų3440.9 Ų40.918%0.18224%0.238CC..Hα-helixtrans-68.9-31.3178.5-87-62.2000111.9Q457 R458 T460 S463 A470Q457-N466 PolarHBondContact O-ND2 3.39Å; R458-N466 PolarHBondContact O-ND2 3.21Å; T460-N466 PolarHBondContact O-ND2 3.26Å; S463-N466 PolarHBondContact OG-N 2.93Å; S463-N466 VanDerWaalsContact OG-N 3.07Å; S463-N466 PolarHBondContact OG-ND2 2.86Å; N466-A470 WeakPolarHBondContact O-CB 3.35Å; N466-A470 PolarHBondContact O-N 2.97Å
467H96.5Very high95.8Very high8 Ų842.1 Ų42.14%0.03724%0.239CC..Hα-helixtrans-64.3-46.1170176.190.3000111.7K363 S463 Y464 L465 K469 A470 L471 H542K363-H467 WeakPolarHBondContact CA-NE2 3.26Å; K363-H467 WeakPolarHBondContact CB-NE2 3.06Å; K363-H467 HydrophobicContact CD-CB 4.25Å; K363-H467 HydrophobicContact CG-CB 4.27Å; K363-H467 PolarHBondContact O-NE2 3.49Å; S463-H467 WeakPolarHBondContact O-CB 3.49Å; S463-H467 PolarHBondContact O-N 2.9Å; Y464-H467 WeakPolarHBondContact O-CB 3.48Å; Y464-H467 PolarHBondContact O-N 3.12Å; L465-H467 VanDerWaalsContact C-N 3.31Å; L465-H467 PolarHBondContact O-N 2.89Å; H467-K469 PolarHBondContact O-N 3.43Å; H467-A470 PolarHBondContact O-N 3.28Å; H467-L471 VanDerWaalsContact NE2-CD1 3.31Å; H467-L471 WeakPolarHBondContact NE2-CD1 3.49Å; H467-L471 WeakPolarHBondContact O-CG 3.48Å; H467-L471 PolarHBondContact O-N 2.85Å; H467-H542 AromaticContact CE1-CD2 3.82Å; H467-H542 AromaticContact CE1-NE2 3.04Å; H467-H542 PolarHBondContact CE1-NE2 3.45Å; H467-H542 AromaticContact CG-NE2 3.89Å; H467-H542 AromaticContact ND1-CE1 3.59Å; H467-H542 AromaticContact ND1-NE2 2.91Å; H467-H542 PolarHBondContact ND1-NE2 3.14Å
468F98.1Very high95.7Very high0 Ų043.3 Ų43.30%025%0.248CC..Hα-helixtrans-59.7-45.7176-172.9-94.4000111.6I21 L54 N366 L370 C378 E383 Y464 L465 A470 L471 L472I21-F468 HydrophobicContact CD1-CE1 4.27Å; I21-F468 HydrophobicContact CD1-CZ 3.92Å; L54-F468 HydrophobicContact CD2-CD1 4.26Å; N366-F468 HydrophobicContact CB-CD2 3.9Å; N366-F468 HydrophobicContact CB-CE2 4.45Å; L370-F468 HydrophobicContact CD1-CD2 3.71Å; L370-F468 HydrophobicContact CD1-CE2 3.65Å; L370-F468 HydrophobicContact CD1-CG 4.23Å; L370-F468 HydrophobicContact CD1-CZ 4.13Å; L370-F468 HydrophobicContact CD2-CE2 4.18Å; L370-F468 HydrophobicContact CD2-CZ 4.2Å; L370-F468 HydrophobicContact CG-CE2 4.17Å; C378-F468 HydrophobicContact CB-CZ 4.13Å; C378-F468 VanDerWaalsContact SG-CZ 3.57Å; E383-F468 HydrophobicContact CB-CB 4.04Å; E383-F468 HydrophobicContact CB-CD1 3.64Å; E383-F468 HydrophobicContact CB-CD2 3.71Å; E383-F468 HydrophobicContact CB-CE1 3.9Å; E383-F468 HydrophobicContact CB-CE2 3.98Å; E383-F468 HydrophobicContact CB-CG 3.54Å; E383-F468 HydrophobicContact CB-CZ 4.07Å; Y464-F468 WeakPolarHBondContact O-CB 3.42Å; Y464-F468 PolarHBondContact O-N 2.91Å; L465-F468 WeakPolarHBondContact O-CB 3.44Å; L465-F468 PolarHBondContact O-N 2.84Å; F468-A470 PolarHBondContact O-N 2.86Å; F468-L471 WeakPolarHBondContact O-CB 3.39Å; F468-L471 PolarHBondContact O-N 2.98Å; F468-L472 HydrophobicContact CD1-CD1 3.84Å; F468-L472 HydrophobicContact CD1-CG 4.15Å; F468-L472 HydrophobicContact CE1-CD1 3.53Å; F468-L472 HydrophobicContact CE1-CD2 4.4Å; F468-L472 HydrophobicContact CE1-CG 3.96Å; F468-L472 HydrophobicContact CZ-CD1 4.48Å; F468-L472 PolarHBondContact O-N 3.03Å
469K98Very high95.6Very high40 Ų4038.1 Ų38.117%0.17423%0.229CC..Hα-helixtrans-59.5-43.2175.2-178.3172.7177.3-70.40112.6W53 L54 L465 H467 L471 L472 Q473W53-K469 HydrophobicContact CD2-CD 4.02Å; W53-K469 HydrophobicContact CE3-CD 4.17Å; W53-K469 HydrophobicContact CH2-CB 4.5Å; W53-K469 HydrophobicContact CH2-CD 3.59Å; W53-K469 HydrophobicContact CZ2-CD 3.39Å; W53-K469 HydrophobicContact CZ3-CD 3.98Å; W53-K469 WeakPolarHBondContact O-CE 3.44Å; L54-K469 HydrophobicContact CD2-CB 4.12Å; L465-K469 PolarHBondContact O-N 3.38Å; H467-K469 PolarHBondContact O-N 3.43Å; K469-L471 VanDerWaalsContact C-N 3.31Å; K469-L471 PolarHBondContact O-N 3.46Å; K469-L472 PolarHBondContact O-N 3.3Å; K469-Q473 WeakPolarHBondContact O-CG 3.42Å; K469-Q473 PolarHBondContact O-N 3.27Å
470A97.1Very high95.6Very high23 Ų2333.8 Ų33.819%0.1920%0.198CC..Hα-helixtrans-62.2-40176.100000111.7N466 H467 F468 Q473 L474N466-A470 WeakPolarHBondContact O-CB 3.35Å; N466-A470 PolarHBondContact O-N 2.97Å; H467-A470 PolarHBondContact O-N 3.28Å; F468-A470 PolarHBondContact O-N 2.86Å; A470-Q473 WeakPolarHBondContact O-CB 3.37Å; A470-Q473 PolarHBondContact O-N 3.35Å; A470-L474 PolarHBondContact O-N 3.24Å; A470-L474 VanDerWaalsContact O-N 3.12Å
471L97.9Very high95.5Very high0 Ų031.2 Ų31.20%018%0.183CC..Hα-helixtrans-65.6-37.3174.5-67172.2000112.6N366 A367 L370 L371 H467 F468 K469 Q473 L474 R475N366-L471 HydrophobicContact CB-CD1 4.1Å; A367-L471 HydrophobicContact CB-CD1 3.92Å; A367-L471 HydrophobicContact CB-CD2 4.08Å; L370-L471 HydrophobicContact CB-CB 4.33Å; L370-L471 HydrophobicContact CD1-CB 3.49Å; L370-L471 VanDerWaalsContact CD1-CB 3.49Å; L370-L471 HydrophobicContact CD1-CD1 4.06Å; L370-L471 HydrophobicContact CD1-CG 4.47Å; L371-L471 HydrophobicContact CD1-CD2 3.83Å; L371-L471 HydrophobicContact CG-CD2 4.23Å; H467-L471 VanDerWaalsContact NE2-CD1 3.31Å; H467-L471 WeakPolarHBondContact NE2-CD1 3.49Å; H467-L471 WeakPolarHBondContact O-CG 3.48Å; H467-L471 PolarHBondContact O-N 2.85Å; F468-L471 WeakPolarHBondContact O-CB 3.39Å; F468-L471 PolarHBondContact O-N 2.98Å; K469-L471 VanDerWaalsContact C-N 3.31Å; K469-L471 PolarHBondContact O-N 3.46Å; L471-Q473 VanDerWaalsContact C-N 3.32Å; L471-Q473 PolarHBondContact O-N 3.45Å; L471-L474 HydrophobicContact CD2-CD1 4.41Å; L471-L474 WeakPolarHBondContact O-CB 3.48Å; L471-L474 PolarHBondContact O-N 3.31Å; L471-R475 WeakPolarHBondContact O-CB 3.16Å; L471-R475 PolarHBondContact O-N 3.01Å
472L97.7Very high95.3Very high14 Ų1433.5 Ų33.57%0.07318%0.182CC..Hα-helixtrans-63.6-37.8173.2-73.8-178.6000112.4I21 L54 V56 L370 F468 K469 L474 R475 A476I21-L472 HydrophobicContact CD1-CD2 4.08Å; I21-L472 HydrophobicContact CG1-CD2 4.24Å; I21-L472 HydrophobicContact CG2-CD2 3.66Å; L54-L472 HydrophobicContact CB-CD1 4.27Å; L54-L472 WeakPolarHBondContact O-CD1 3.2Å; V56-L472 HydrophobicContact CG2-CD1 4.05Å; L370-L472 HydrophobicContact CD1-CD2 4.13Å; L370-L472 HydrophobicContact CD1-CG 4.26Å; L370-L472 HydrophobicContact CD2-CD2 3.74Å; F468-L472 HydrophobicContact CD1-CD1 3.84Å; F468-L472 HydrophobicContact CD1-CG 4.15Å; F468-L472 HydrophobicContact CE1-CD1 3.53Å; F468-L472 HydrophobicContact CE1-CD2 4.4Å; F468-L472 HydrophobicContact CE1-CG 3.96Å; F468-L472 HydrophobicContact CZ-CD1 4.48Å; F468-L472 PolarHBondContact O-N 3.03Å; K469-L472 PolarHBondContact O-N 3.3Å; L472-L474 VanDerWaalsContact C-N 3.32Å; L472-L474 PolarHBondContact O-N 3.06Å; L472-R475 PolarHBondContact O-N 3.28Å; L472-A476 PolarHBondContact O-N 3.48Å
473Q96.7Very high95.1Very high114 Ų11431 Ų3153%0.53316%0.164SC..Hα-helixtrans-63.3-38.7174-69.1174-34.800111.8K469 A470 L471K469-Q473 WeakPolarHBondContact O-CG 3.42Å; K469-Q473 PolarHBondContact O-N 3.27Å; A470-Q473 WeakPolarHBondContact O-CB 3.37Å; A470-Q473 PolarHBondContact O-N 3.35Å; L471-Q473 VanDerWaalsContact C-N 3.32Å; L471-Q473 PolarHBondContact O-N 3.45Å
474L96.4Very high94.9Very high15 Ų1530.5 Ų30.58%0.07916%0.161CC..Hα-helixtrans-66.3-44.4172.4-66.5174.5000111.9L371 A470 L471 L472 A476 L477 F480 V541 H542 V568L371-L474 HydrophobicContact CD2-CB 4.08Å; A470-L474 PolarHBondContact O-N 3.24Å; A470-L474 VanDerWaalsContact O-N 3.12Å; L471-L474 HydrophobicContact CD2-CD1 4.41Å; L471-L474 WeakPolarHBondContact O-CB 3.48Å; L471-L474 PolarHBondContact O-N 3.31Å; L472-L474 VanDerWaalsContact C-N 3.32Å; L472-L474 PolarHBondContact O-N 3.06Å; L474-A476 PolarHBondContact O-N 3.07Å; L474-L477 HydrophobicContact CD2-CD1 4.1Å; L474-L477 VanDerWaalsContact O-CB 3.22Å; L474-L477 WeakPolarHBondContact O-CB 3.44Å; L474-L477 VanDerWaalsContact O-CG 3.3Å; L474-L477 WeakPolarHBondContact O-CG 3.33Å; L474-L477 PolarHBondContact O-N 2.79Å; L474-F480 HydrophobicContact CB-CE2 4.36Å; L474-F480 WeakPolarHBondContact O-CD2 3.38Å; L474-V541 HydrophobicContact CD2-CG1 3.42Å; L474-V541 VanDerWaalsContact CD2-CG1 3.42Å; L474-H542 HydrophobicContact CD1-CB 3.93Å; L474-V568 HydrophobicContact CD1-CB 4.18Å; L474-V568 HydrophobicContact CD1-CG1 4.13Å; L474-V568 HydrophobicContact CD1-CG2 4.04Å
475R95.7Very high94.5Very high10 Ų1032 Ų324%0.03817%0.172CC..Hα-helixtrans-58.3-33.3178.8-176.2178.6171.476.76.8112.5T20 I21 L370 G374 L471 L472 L477 F480 A481T20-R475 PolarHBondContact O-NH2 2.79Å; I21-R475 VanDerWaalsContact CG2-NE 3.29Å; L370-R475 WeakPolarHBondContact O-CD 3.11Å; L370-R475 PolarHBondContact O-NH1 2.84Å; G374-R475 PolarHBondContact O-NH1 3.05Å; G374-R475 VanDerWaalsContact O-NH1 3.14Å; G374-R475 PolarHBondContact O-NH2 2.64Å; L471-R475 WeakPolarHBondContact O-CB 3.16Å; L471-R475 PolarHBondContact O-N 3.01Å; L472-R475 PolarHBondContact O-N 3.28Å; R475-L477 PolarHBondContact O-N 3.26Å; R475-F480 WeakPolarHBondContact O-CB 3.5Å; R475-A481 WeakPolarHBondContact O-CB 3.2Å; R475-A481 PolarHBondContact O-N 3.4Å
476A94.4Very high94Very high70 Ų7032.7 Ų32.758%0.57918%0.176SC*.THydrogen-bonded Turntrans-68.9-11.9176.200000114L472 L474L472-A476 PolarHBondContact O-N 3.48Å; L474-A476 PolarHBondContact O-N 3.07Å
477L94.7Very high93.9Very high64 Ų6432 Ų3234%0.33517%0.174SC..SBendtrans-69.9144174.6-59.7173.5000110.5L474 R475 T479 F480 A481 F510L474-L477 HydrophobicContact CD2-CD1 4.1Å; L474-L477 VanDerWaalsContact O-CB 3.22Å; L474-L477 WeakPolarHBondContact O-CB 3.44Å; L474-L477 VanDerWaalsContact O-CG 3.3Å; L474-L477 WeakPolarHBondContact O-CG 3.33Å; L474-L477 PolarHBondContact O-N 2.79Å; R475-L477 PolarHBondContact O-N 3.26Å; L477-T479 VanDerWaalsContact C-N 3.25Å; L477-T479 PolarHBondContact O-N 2.85Å; L477-T479 VanDerWaalsContact O-N 3.07Å; L477-F480 HydrophobicContact CB-CD2 4.29Å; L477-F480 PolarHBondContact O-N 3.39Å; L477-A481 PolarHBondContact O-N 2.93Å; L477-F510 HydrophobicContact CD1-CE1 4.17Å; L477-F510 HydrophobicContact CD1-CE2 4.08Å; L477-F510 HydrophobicContact CD1-CZ 3.54Å
478P93.5Very high93.9Very high36 Ų3636.6 Ų36.623%0.23420%0.195CC..Hα-helixtrans-48.8-41.6-177.6-33.437.9000114.8F480 A481 Y482 L504 F507P478-F480 VanDerWaalsContact C-N 3.25Å; P478-F480 PolarHBondContact O-N 3.21Å; P478-A481 PolarHBondContact O-N 3.43Å; P478-Y482 HydrophobicContact CB-CD2 3.72Å; P478-Y482 HydrophobicContact CB-CE2 3.95Å; P478-Y482 HydrophobicContact CG-CD2 4.43Å; P478-Y482 HydrophobicContact CG-CE2 4.14Å; P478-Y482 PolarHBondContact O-N 3.48Å; P478-L504 HydrophobicContact CB-CD2 4.26Å; P478-L504 WeakPolarHBondContact O-CD2 3.29Å; P478-F507 HydrophobicContact CB-CD1 3.49Å; P478-F507 VanDerWaalsContact CB-CD1 3.49Å; P478-F507 HydrophobicContact CB-CD2 4.18Å; P478-F507 HydrophobicContact CB-CE1 3.43Å; P478-F507 VanDerWaalsContact CB-CE1 3.43Å; P478-F507 HydrophobicContact CB-CE2 4.13Å; P478-F507 HydrophobicContact CB-CG 3.87Å; P478-F507 HydrophobicContact CB-CZ 3.76Å; P478-F507 HydrophobicContact CG-CD1 3.74Å; P478-F507 HydrophobicContact CG-CE1 3.5Å; P478-F507 VanDerWaalsContact CG-CE1 3.5Å; P478-F507 HydrophobicContact CG-CZ 4.16Å
479T94.6Very high93.8Very high2 Ų239.1 Ų39.11%0.01221%0.207CC..Hα-helixtrans-59-34.6179.9-53.40000113.4L477 R502 L504 F507 A508 F510L477-T479 VanDerWaalsContact C-N 3.25Å; L477-T479 PolarHBondContact O-N 2.85Å; L477-T479 VanDerWaalsContact O-N 3.07Å; T479-R502 HydrophobicContact CG2-CB 3.87Å; T479-R502 VanDerWaalsContact CG2-O 3.23Å; T479-R502 WeakPolarHBondContact CG2-O 3.39Å; T479-R502 PolarHBondContact O-NH2 3.43Å; T479-L504 HydrophobicContact CG2-CB 4.19Å; T479-F507 WeakPolarHBondContact OG1-CB 3.37Å; T479-A508 WeakPolarHBondContact CG2-O 3.49Å; T479-A508 PolarHBondContact OG1-O 2.96Å; T479-F510 HydrophobicContact CG2-CD2 3.94Å
480F94.6Very high93.6Very high1 Ų137.9 Ų37.90%0.00420%0.203CC..Hα-helixtrans-90-43.1178.9-68.3-79.1000111.9L371 L474 R475 L477 P478 R502 F510 V512 V568L371-F480 HydrophobicContact CB-CD1 4.19Å; L371-F480 HydrophobicContact CB-CE1 3.88Å; L371-F480 HydrophobicContact CD1-CE1 4.46Å; L371-F480 HydrophobicContact CD2-CD1 3.91Å; L371-F480 HydrophobicContact CD2-CE1 3.78Å; L371-F480 HydrophobicContact CD2-CG 4.43Å; L371-F480 HydrophobicContact CD2-CZ 4.18Å; L371-F480 HydrophobicContact CG-CE1 4.25Å; L474-F480 HydrophobicContact CB-CE2 4.36Å; L474-F480 WeakPolarHBondContact O-CD2 3.38Å; R475-F480 WeakPolarHBondContact O-CB 3.5Å; L477-F480 HydrophobicContact CB-CD2 4.29Å; L477-F480 PolarHBondContact O-N 3.39Å; P478-F480 VanDerWaalsContact C-N 3.25Å; P478-F480 PolarHBondContact O-N 3.21Å; F480-R502 HydrophobicContact CD1-CB 4.38Å; F480-R502 HydrophobicContact CD1-CG 3.86Å; F480-R502 HydrophobicContact CE1-CB 4.14Å; F480-R502 HydrophobicContact CE1-CG 3.6Å; F480-R502 PolarHBondContact O-NH2 2.92Å; F480-F510 HydrophobicContact CD2-CD2 4.26Å; F480-F510 HydrophobicContact CE1-CB 4.44Å; F480-F510 HydrophobicContact CE2-CB 3.9Å; F480-F510 HydrophobicContact CE2-CD1 4.01Å; F480-F510 AromaticContact CE2-CD2 3.54Å; F480-F510 HydrophobicContact CE2-CD2 3.54Å; F480-F510 HydrophobicContact CE2-CE1 4.45Å; F480-F510 HydrophobicContact CE2-CE2 4.04Å; F480-F510 AromaticContact CE2-CG 3.53Å; F480-F510 HydrophobicContact CE2-CG 3.53Å; F480-F510 HydrophobicContact CE2-CZ 4.47Å; F480-F510 HydrophobicContact CZ-CB 3.5Å; F480-F510 HydrophobicContact CZ-CD1 4.29Å; F480-F510 HydrophobicContact CZ-CD2 4.06Å; F480-F510 AromaticContact CZ-CG 3.7Å; F480-F510 HydrophobicContact CZ-CG 3.7Å; F480-V512 HydrophobicContact CE1-CG2 4.2Å; F480-V512 HydrophobicContact CZ-CG2 4.46Å; F480-V568 HydrophobicContact CZ-CG1 4.45Å
481A92.2Very high93.4Very high7 Ų740.9 Ų40.96%0.05823%0.228CC..Hα-helixtrans-72-46.7-174.700000113.9R475 L477 P478 S483R475-A481 WeakPolarHBondContact O-CB 3.2Å; R475-A481 PolarHBondContact O-N 3.4Å; L477-A481 PolarHBondContact O-N 2.93Å; P478-A481 PolarHBondContact O-N 3.43Å; A481-S483 VanDerWaalsContact C-N 3.32Å; A481-S483 PolarHBondContact O-N 3.19Å
482Y87.5Confident93.2Very high131 Ų13142.2 Ų42.251%0.51424%0.237SC..THydrogen-bonded Turntrans-94.229-166.5-56.7-41.1000114.2E19 P478E19-Y482 HydrophobicContact CG-CE1 4.23Å; P478-Y482 HydrophobicContact CB-CD2 3.72Å; P478-Y482 HydrophobicContact CB-CE2 3.95Å; P478-Y482 HydrophobicContact CG-CD2 4.43Å; P478-Y482 HydrophobicContact CG-CE2 4.14Å; P478-Y482 PolarHBondContact O-N 3.48Å
483S86.6Confident92.8Very high17 Ų1747 Ų4712%0.11927%0.268CS..  trans-150.5137.6176-171.20000113.7P373 G374 A481 N486 R502P373-S483 VanDerWaalsContact CB-O 3.31Å; P373-S483 WeakPolarHBondContact CB-O 3.43Å; G374-S483 PolarHBondContact N-O 2.9Å; A481-S483 VanDerWaalsContact C-N 3.32Å; A481-S483 PolarHBondContact O-N 3.19Å; S483-N486 WeakPolarHBondContact OG-CB 3.33Å; S483-N486 PolarHBondContact OG-N 3.03Å; S483-R502 PolarHBondContact O-NH2 2.85Å
484S89.9Confident92.7Very high3 Ų343.9 Ų43.92%0.02125%0.254CS..SBendtrans-102.8-21.1178.2173.80000113.8Q331 K338 W339 S340 P373Q331-S484 PolarHBondContact NE2-O 3.1Å; Q331-S484 VanDerWaalsContact NE2-O 3.12Å; Q331-S484 PolarHBondContact OE1-O 3.14Å; K338-S484 PolarHBondContact O-OG 2.62Å; W339-S484 WeakPolarHBondContact CA-OG 3.37Å; S340-S484 PolarHBondContact N-OG 3.22Å; S340-S484 PolarHBondContact OG-O 3.38Å; S340-S484 PolarHBondContact OG-OG 3.41Å; P373-S484 WeakPolarHBondContact CB-O 3.31Å; P373-S484 WeakPolarHBondContact CG-O 3.22Å
485D88.9Confident92.5Very high82 Ų8251.6 Ų51.644%0.43929%0.289SS..SBendtrans-112.9-18.3-170.6-48.1-61.2000113.1K334 V487K334-D485 WeakPolarHBondContact CE-OD1 3.29Å; K334-D485 IonicContact NZ-OD1 3.09Å; K334-D485 PolarHBondContact NZ-OD1 3.43Å; D485-V487 PolarHBondContact O-N 2.91Å
486N87Confident92.4Very high15 Ų1553.4 Ų53.48%0.0830%0.301CS..  trans-75.584-174.8168.430.4000111.5S483 R502 K503S483-N486 WeakPolarHBondContact OG-CB 3.33Å; S483-N486 PolarHBondContact OG-N 3.03Å; N486-R502 WeakPolarHBondContact O-CD 3.08Å; N486-R502 PolarHBondContact O-NE 2.93Å; N486-K503 PolarHBondContact ND2-N 3.35Å; N486-K503 PolarHBondContact ND2-O 3.05Å; N486-K503 PolarHBondContact OD1-N 3.04Å; N486-K503 PolarHBondContact OD1-O 3.07Å; N486-K503 VanDerWaalsContact OD1-O 3.05Å
487V94.5Very high92.5Very high21 Ų2150.3 Ų50.313%0.12728%0.275CS..  trans-142120.6167.9590000109.5Q331 L372 P373 D485 I489 F500Q331-V487 HydrophobicContact CG-CG1 3.76Å; L372-V487 HydrophobicContact CD2-CG2 4.26Å; P373-V487 HydrophobicContact CG-CB 3.94Å; P373-V487 HydrophobicContact CG-CG1 3.9Å; D485-V487 PolarHBondContact O-N 2.91Å; V487-I489 HydrophobicContact CG2-CD1 4.28Å; V487-F500 HydrophobicContact CG2-CB 3.91Å; V487-F500 HydrophobicContact CG2-CD2 3.87Å; V487-F500 HydrophobicContact CG2-CG 4.05Å
488H95.3Very high92.7Very high103 Ų10347.2 Ų47.248%0.47726%0.259SS..EExtended strand (participates in β ladder)trans-116.3111.3175.3-58.5-72.9000109.4I490 F500 S501H488-I490 PolarHBondContact O-N 3.47Å; H488-F500 CarbonylContact O-C 3.54Å; H488-F500 WeakPolarHBondContact O-CA 3.23Å; H488-S501 PolarHBondContact N-O 3.1Å; H488-S501 VanDerWaalsContact N-O 3.08Å; H488-S501 PolarHBondContact O-N 2.87Å
489I96.3Very high92.9Very high53 Ų5345.5 Ų45.527%0.27225%0.248SC..EExtended strand (participates in β ladder)trans-66.9131.3176.7-54.8-58.4000109.3I324 I327 V487 F500I324-I489 HydrophobicContact CD1-CG2 4.08Å; I324-I489 HydrophobicContact CG1-CG2 4.2Å; I324-I489 HydrophobicContact CG2-CG1 4.25Å; I324-I489 HydrophobicContact CG2-CG2 3.95Å; I327-I489 HydrophobicContact CG2-CD1 4.44Å; V487-I489 HydrophobicContact CG2-CD1 4.28Å; I489-F500 HydrophobicContact CD1-CB 4.01Å
490I95Very high93Very high15 Ų1545.4 Ų45.48%0.07725%0.248CC..EExtended strand (participates in β ladder)trans-100.7119177.3-53.2-51.6000108.2H488 C492 A499 L511 L528 S530 V531H488-I490 PolarHBondContact O-N 3.47Å; I490-C492 PolarHBondContact O-N 3.33Å; I490-A499 HydrophobicContact CB-CB 3.98Å; I490-A499 PolarHBondContact N-O 3.14Å; I490-L511 HydrophobicContact CG1-CD1 3.79Å; I490-L528 HydrophobicContact CG2-CD2 4.35Å; I490-S530 WeakPolarHBondContact CG2-OG 3.34Å; I490-V531 HydrophobicContact CD1-CB 4.18Å; I490-V531 HydrophobicContact CD1-CG2 3.99Å; I490-V531 HydrophobicContact CG1-CB 4.45Å; I490-V531 HydrophobicContact CG1-CG2 4.29Å
491A92.3Very high93.1Very high86 Ų8645.4 Ų45.471%0.71125%0.248SC*.PPolyproline II helixtrans-63.9121.217900000110.3
492C92.8Very high93.3Very high28 Ų2845.1 Ų45.119%0.18925%0.245CC..  trans-119.6132.6174.2-63.20000108.6I490 Q494 V497I490-C492 PolarHBondContact O-N 3.33Å; C492-Q494 PolarHBondContact O-N 3.38Å; C492-V497 HydrophobicContact CB-CB 4.13Å; C492-V497 HydrophobicContact CB-CG1 4.05Å
493P90.8Very high93.6Very high113 Ų11342.3 Ų42.373%0.73424%0.236SC*.SBendtrans-70.6-17.7177.323.9-28.9000113.2
494Q93.3Very high94Very high50 Ų5043.5 Ų43.523%0.23424%0.24CC..SBendtrans-79.6118.5177-64.675.223.200110.9C492 T496 V497 L524 K525 I526C492-Q494 PolarHBondContact O-N 3.38Å; Q494-T496 PolarHBondContact O-N 2.99Å; Q494-T496 VanDerWaalsContact O-N 3.09Å; Q494-V497 HydrophobicContact CB-CB 4.2Å; Q494-V497 HydrophobicContact CB-CG2 3.73Å; Q494-V497 PolarHBondContact O-N 3.36Å; Q494-L524 HydrophobicContact CB-CD1 4.29Å; Q494-L524 HydrophobicContact CG-CD1 4.32Å; Q494-L524 HydrophobicContact CG-CD2 4.49Å; Q494-K525 PolarHBondContact NE2-O 2.72Å; Q494-I526 HydrophobicContact CG-CG2 4.22Å
495E92.5Very high94Very high177 Ų17751 Ų5183%0.82728%0.28SS*.THydrogen-bonded Turntrans-61-23.5-174.3-61.8-174.3168.100114.5T320T320-E495 WeakPolarHBondContact CB-O 3.27Å; T320-E495 PolarHBondContact OG1-O 2.8Å
496T94.2Very high94.2Very high47 Ų4751.2 Ų51.229%0.28830%0.302SS..THydrogen-bonded Turntrans-91.6-0.4179.865.40000113.4Q494 N515 L516 A517Q494-T496 PolarHBondContact O-N 2.99Å; Q494-T496 VanDerWaalsContact O-N 3.09Å; T496-N515 WeakPolarHBondContact CB-OD1 3.43Å; T496-N515 PolarHBondContact O-OD1 2.96Å; T496-N515 PolarHBondContact OG1-OD1 3.37Å; T496-L516 PolarHBondContact O-N 3.15Å; T496-A517 HydrophobicContact CG2-CB 3.95Å
497V96.5Very high94.5Very high5 Ų555.6 Ų55.63%0.0332%0.321CS..EExtended strand (participates in β ladder)trans-104.1117.6-174.4179.70000110.8T320 C492 Q494 V513 L514 L524 I526 L561T320-V497 WeakPolarHBondContact CG2-O 3.19Å; C492-V497 HydrophobicContact CB-CB 4.13Å; C492-V497 HydrophobicContact CB-CG1 4.05Å; Q494-V497 HydrophobicContact CB-CB 4.2Å; Q494-V497 HydrophobicContact CB-CG2 3.73Å; Q494-V497 PolarHBondContact O-N 3.36Å; V497-V513 HydrophobicContact CG1-CG1 3.91Å; V497-L514 CarbonylContact C-O 3.58Å; V497-L514 WeakPolarHBondContact CA-O 3.24Å; V497-L524 HydrophobicContact CG2-CD1 3.85Å; V497-I526 HydrophobicContact CG2-CG2 4.35Å; V497-L561 HydrophobicContact CG2-CD1 4.33Å
498L97.5Very high94.5Very high0 Ų056.3 Ų56.30%033%0.329CS..EExtended strand (participates in β ladder)trans-104.2114.8169.1-163.4164.6000108T320 L323 I324 I327 L368 F500 L514 L516T320-L498 HydrophobicContact CG2-CB 3.62Å; T320-L498 HydrophobicContact CG2-CD1 4.33Å; T320-L498 HydrophobicContact CG2-CG 4.06Å; L323-L498 HydrophobicContact CB-CD1 3.89Å; L323-L498 HydrophobicContact CD1-CD1 4.27Å; I324-L498 HydrophobicContact CG1-CD1 4.3Å; I324-L498 HydrophobicContact CG1-CG 4.06Å; I327-L498 HydrophobicContact CD1-CD1 4.25Å; L368-L498 HydrophobicContact CD1-CD1 4.21Å; L368-L498 HydrophobicContact CD1-CD2 4.27Å; L498-F500 HydrophobicContact CD2-CD1 3.6Å; L498-F500 HydrophobicContact CD2-CE1 4.17Å; L498-L514 HydrophobicContact CB-CB 4.34Å; L498-L514 PolarHBondContact N-O 2.84Å; L498-L514 PolarHBondContact O-N 3.01Å; L498-L516 HydrophobicContact CB-CD1 3.77Å
499A97.8Very high94.5Very high0 Ų052.8 Ų52.80%032%0.315CS..EExtended strand (participates in β ladder)trans-122.8138.3176.600000111.2I490 L511 V512 V513 L528I490-A499 HydrophobicContact CB-CB 3.98Å; I490-A499 PolarHBondContact N-O 3.14Å; A499-L511 HydrophobicContact CB-CD1 4.48Å; A499-V512 CarbonylContact C-O 3.49Å; A499-V512 VanDerWaalsContact CA-O 3.24Å; A499-V512 WeakPolarHBondContact CA-O 3.34Å; A499-V513 HydrophobicContact CB-CG1 4.32Å; A499-L528 HydrophobicContact CB-CD2 4.28Å
500F97.7Very high94.6Very high0 Ų050.7 Ų50.70%030%0.304CS..EExtended strand (participates in β ladder)trans-148.5149.417465-91.2000111.7L368 L371 L372 V487 H488 I489 L498 R502 L511 V512L368-F500 HydrophobicContact CD1-CE1 4.03Å; L371-F500 HydrophobicContact CB-CE2 4.4Å; L371-F500 HydrophobicContact CB-CZ 4.05Å; L371-F500 VanDerWaalsContact O-CE2 3.31Å; L371-F500 WeakPolarHBondContact O-CE2 3.49Å; L372-F500 HydrophobicContact CD2-CE1 4.47Å; L372-F500 HydrophobicContact CD2-CZ 4.33Å; L372-F500 HydrophobicContact CG-CZ 4.48Å; V487-F500 HydrophobicContact CG2-CB 3.91Å; V487-F500 HydrophobicContact CG2-CD2 3.87Å; V487-F500 HydrophobicContact CG2-CG 4.05Å; H488-F500 CarbonylContact O-C 3.54Å; H488-F500 WeakPolarHBondContact O-CA 3.23Å; I489-F500 HydrophobicContact CD1-CB 4.01Å; L498-F500 HydrophobicContact CD2-CD1 3.6Å; L498-F500 HydrophobicContact CD2-CE1 4.17Å; F500-R502 HydrophobicContact CD2-CG 4.24Å; F500-R502 HydrophobicContact CE2-CG 4.06Å; F500-L511 WeakPolarHBondContact O-CD1 3.34Å; F500-V512 HydrophobicContact CD1-CB 4.2Å; F500-V512 HydrophobicContact CD1-CG1 4.5Å; F500-V512 HydrophobicContact CD2-CB 4.23Å; F500-V512 HydrophobicContact CD2-CG2 4.34Å; F500-V512 HydrophobicContact CE1-CB 3.79Å; F500-V512 HydrophobicContact CE1-CG1 3.74Å; F500-V512 HydrophobicContact CE1-CG2 4.48Å; F500-V512 HydrophobicContact CE2-CB 3.8Å; F500-V512 HydrophobicContact CE2-CG1 4.4Å; F500-V512 HydrophobicContact CE2-CG2 3.67Å; F500-V512 HydrophobicContact CG-CB 4.42Å; F500-V512 HydrophobicContact CZ-CB 3.59Å; F500-V512 HydrophobicContact CZ-CG1 3.7Å; F500-V512 HydrophobicContact CZ-CG2 3.78Å; F500-V512 PolarHBondContact N-O 2.88Å; F500-V512 PolarHBondContact O-N 2.88Å
501S96.9Very high94.7Very high1 Ų150 Ų501%0.00730%0.3CS..EExtended strand (participates in β ladder)trans-105.2150.6174.870.50000112.7H488 F510H488-S501 PolarHBondContact N-O 3.1Å; H488-S501 VanDerWaalsContact N-O 3.08Å; H488-S501 PolarHBondContact O-N 2.87Å; S501-F510 CarbonylContact C-O 3.56Å; S501-F510 WeakPolarHBondContact CA-O 3.44Å; S501-F510 WeakPolarHBondContact CB-O 3.49Å
502R96.5Very high95Very high0 Ų045.9 Ų45.90%027%0.266CS..EExtended strand (participates in β ladder)trans-120.6117.2172.4-57.7-68.4-54.9-86.2-3.2107.8L371 L372 T479 F480 S483 N486 F500 T509 F510L371-R502 PolarHBondContact O-NH1 2.94Å; L372-R502 PolarHBondContact O-NH1 3.41Å; T479-R502 HydrophobicContact CG2-CB 3.87Å; T479-R502 VanDerWaalsContact CG2-O 3.23Å; T479-R502 WeakPolarHBondContact CG2-O 3.39Å; T479-R502 PolarHBondContact O-NH2 3.43Å; F480-R502 HydrophobicContact CD1-CB 4.38Å; F480-R502 HydrophobicContact CD1-CG 3.86Å; F480-R502 HydrophobicContact CE1-CB 4.14Å; F480-R502 HydrophobicContact CE1-CG 3.6Å; F480-R502 PolarHBondContact O-NH2 2.92Å; S483-R502 PolarHBondContact O-NH2 2.85Å; N486-R502 WeakPolarHBondContact O-CD 3.08Å; N486-R502 PolarHBondContact O-NE 2.93Å; F500-R502 HydrophobicContact CD2-CG 4.24Å; F500-R502 HydrophobicContact CE2-CG 4.06Å; R502-T509 WeakPolarHBondContact O-CA 3.21Å; R502-F510 PolarHBondContact N-O 3.32Å; R502-F510 PolarHBondContact O-N 3.28Å
503K94.1Very high95.2Very high73 Ų7344.6 Ų44.632%0.31726%0.257SS..  trans-122.8122.7-179.7-60-170.7-179.1-172.90112.5N486 T509 V531N486-K503 PolarHBondContact ND2-N 3.35Å; N486-K503 PolarHBondContact ND2-O 3.05Å; N486-K503 PolarHBondContact OD1-N 3.04Å; N486-K503 PolarHBondContact OD1-O 3.07Å; N486-K503 VanDerWaalsContact OD1-O 3.05Å; K503-T509 HydrophobicContact CD-CG2 4.23Å; K503-T509 HydrophobicContact CG-CG2 3.61Å; K503-V531 PolarHBondContact NZ-O 3.48Å
504L93.1Very high95.5Very high42 Ų4239.2 Ų39.222%0.2222%0.222CC..  trans-126.8128.5172.6-176.167.1000109.1P478 T479 G506 F507P478-L504 HydrophobicContact CB-CD2 4.26Å; P478-L504 WeakPolarHBondContact O-CD2 3.29Å; T479-L504 HydrophobicContact CG2-CB 4.19Å; L504-G506 PolarHBondContact O-N 3Å; L504-F507 HydrophobicContact CB-CB 4.36Å; L504-F507 HydrophobicContact CB-CD2 4.18Å; L504-F507 HydrophobicContact CD2-CD2 3.48Å; L504-F507 VanDerWaalsContact CD2-CD2 3.48Å; L504-F507 HydrophobicContact CD2-CE2 3.78Å; L504-F507 HydrophobicContact CD2-CG 4.26Å; L504-F507 HydrophobicContact CG-CD2 3.69Å; L504-F507 HydrophobicContact CG-CE2 4.25Å; L504-F507 PolarHBondContact O-N 3.46Å
505N91.3Very high95.6Very high159 Ų15936.8 Ų36.885%0.8521%0.211SC*.THydrogen-bonded Turntrans-54.9129.6-177.2-72.5-17.9000111.2F507N505-F507 VanDerWaalsContact C-N 3.29Å; N505-F507 WeakPolarHBondContact O-CD2 3.32Å; N505-F507 PolarHBondContact O-N 3.25Å
506G92.3Very high95.7Very high88 Ų8829.5 Ų29.591%0.90718%0.178SC*.THydrogen-bonded Turntrans82.9-3.9-177.400000115.2L504L504-G506 PolarHBondContact O-N 3Å
507F94.5Very high95.6Very high106 Ų10627.8 Ų27.847%0.46517%0.168SC..SBendtrans-121.1168.7179-59.9-84.8000112P478 T479 L504 N505P478-F507 HydrophobicContact CB-CD1 3.49Å; P478-F507 VanDerWaalsContact CB-CD1 3.49Å; P478-F507 HydrophobicContact CB-CD2 4.18Å; P478-F507 HydrophobicContact CB-CE1 3.43Å; P478-F507 VanDerWaalsContact CB-CE1 3.43Å; P478-F507 HydrophobicContact CB-CE2 4.13Å; P478-F507 HydrophobicContact CB-CG 3.87Å; P478-F507 HydrophobicContact CB-CZ 3.76Å; P478-F507 HydrophobicContact CG-CD1 3.74Å; P478-F507 HydrophobicContact CG-CE1 3.5Å; P478-F507 VanDerWaalsContact CG-CE1 3.5Å; P478-F507 HydrophobicContact CG-CZ 4.16Å; T479-F507 WeakPolarHBondContact OG1-CB 3.37Å; L504-F507 HydrophobicContact CB-CB 4.36Å; L504-F507 HydrophobicContact CB-CD2 4.18Å; L504-F507 HydrophobicContact CD2-CD2 3.48Å; L504-F507 VanDerWaalsContact CD2-CD2 3.48Å; L504-F507 HydrophobicContact CD2-CE2 3.78Å; L504-F507 HydrophobicContact CD2-CG 4.26Å; L504-F507 HydrophobicContact CG-CD2 3.69Å; L504-F507 HydrophobicContact CG-CE2 4.25Å; L504-F507 PolarHBondContact O-N 3.46Å; N505-F507 VanDerWaalsContact C-N 3.29Å; N505-F507 WeakPolarHBondContact O-CD2 3.32Å; N505-F507 PolarHBondContact O-N 3.25Å
508A94.1Very high95.2Very high37 Ų3731.1 Ų31.131%0.30619%0.192SC..  trans-65.5140.8178.200000111.3T479 F510 K570T479-A508 WeakPolarHBondContact CG2-O 3.49Å; T479-A508 PolarHBondContact OG1-O 2.96Å; A508-F510 HydrophobicContact CB-CE2 3.89Å; A508-F510 HydrophobicContact CB-CZ 4.06Å; A508-F510 WeakPolarHBondContact O-CD2 3.16Å; A508-F510 WeakPolarHBondContact O-CE2 3.4Å; A508-K570 HydrophobicContact CB-CD 4.26Å; A508-K570 HydrophobicContact CB-CG 4.17Å
509T95.3Very high94.4Very high28 Ų2833.9 Ų33.917%0.17221%0.211CC..  trans-85136.6170.9-69.30000109.8R502 K503 I571R502-T509 WeakPolarHBondContact O-CA 3.21Å; K503-T509 HydrophobicContact CD-CG2 4.23Å; K503-T509 HydrophobicContact CG-CG2 3.61Å; T509-I571 HydrophobicContact CG2-CB 4.07Å; T509-I571 HydrophobicContact CG2-CG1 3.65Å; T509-I571 PolarHBondContact O-N 3.27Å
510F96.9Very high93.7Very high10 Ų1045.7 Ų45.74%0.04426%0.256CS..EExtended strand (participates in β ladder)trans-117.4146.4175.2-64-89.7000111.2L477 T479 F480 S501 R502 A508 V541 V568 L569 K570L477-F510 HydrophobicContact CD1-CE1 4.17Å; L477-F510 HydrophobicContact CD1-CE2 4.08Å; L477-F510 HydrophobicContact CD1-CZ 3.54Å; T479-F510 HydrophobicContact CG2-CD2 3.94Å; F480-F510 HydrophobicContact CD2-CD2 4.26Å; F480-F510 HydrophobicContact CE1-CB 4.44Å; F480-F510 HydrophobicContact CE2-CB 3.9Å; F480-F510 HydrophobicContact CE2-CD1 4.01Å; F480-F510 AromaticContact CE2-CD2 3.54Å; F480-F510 HydrophobicContact CE2-CD2 3.54Å; F480-F510 HydrophobicContact CE2-CE1 4.45Å; F480-F510 HydrophobicContact CE2-CE2 4.04Å; F480-F510 AromaticContact CE2-CG 3.53Å; F480-F510 HydrophobicContact CE2-CG 3.53Å; F480-F510 HydrophobicContact CE2-CZ 4.47Å; F480-F510 HydrophobicContact CZ-CB 3.5Å; F480-F510 HydrophobicContact CZ-CD1 4.29Å; F480-F510 HydrophobicContact CZ-CD2 4.06Å; F480-F510 AromaticContact CZ-CG 3.7Å; F480-F510 HydrophobicContact CZ-CG 3.7Å; S501-F510 CarbonylContact C-O 3.56Å; S501-F510 WeakPolarHBondContact CA-O 3.44Å; S501-F510 WeakPolarHBondContact CB-O 3.49Å; R502-F510 PolarHBondContact N-O 3.32Å; R502-F510 PolarHBondContact O-N 3.28Å; A508-F510 HydrophobicContact CB-CE2 3.89Å; A508-F510 HydrophobicContact CB-CZ 4.06Å; A508-F510 WeakPolarHBondContact O-CD2 3.16Å; A508-F510 WeakPolarHBondContact O-CE2 3.4Å; F510-V541 HydrophobicContact CE1-CG2 4.23Å; F510-V568 HydrophobicContact CD1-CG1 4.33Å; F510-L569 CarbonylContact C-O 3.58Å; F510-L569 WeakPolarHBondContact CA-O 3.45Å; F510-K570 HydrophobicContact CD1-CB 4.09Å; F510-K570 HydrophobicContact CE1-CB 3.91Å; F510-K570 HydrophobicContact CE1-CG 4.26Å
511L97.6Very high93.1Very high0 Ų047.1 Ų47.10%027%0.267CS..EExtended strand (participates in β ladder)trans-119.3122.3171.8173.461.1000108.2I490 A499 F500 V513 L528 V531 L556 V568 L569 I571I490-L511 HydrophobicContact CG1-CD1 3.79Å; A499-L511 HydrophobicContact CB-CD1 4.48Å; F500-L511 WeakPolarHBondContact O-CD1 3.34Å; L511-V513 HydrophobicContact CD1-CG2 4.46Å; L511-V513 HydrophobicContact CD2-CG2 4.35Å; L511-V513 HydrophobicContact CG-CG2 3.91Å; L511-L528 HydrophobicContact CD2-CB 3.9Å; L511-L528 HydrophobicContact CD2-CD1 3.63Å; L511-L528 HydrophobicContact CD2-CG 4.27Å; L511-L528 HydrophobicContact CG-CD1 4.45Å; L511-V531 HydrophobicContact CB-CG2 4.46Å; L511-V531 HydrophobicContact CD1-CG2 4.11Å; L511-V531 HydrophobicContact CD2-CB 4.22Å; L511-V531 HydrophobicContact CD2-CG1 4.21Å; L511-V531 HydrophobicContact CD2-CG2 4.22Å; L511-L556 HydrophobicContact CD2-CD2 4.2Å; L511-V568 WeakPolarHBondContact O-CA 3.35Å; L511-L569 HydrophobicContact CB-CB 4.25Å; L511-L569 HydrophobicContact CD2-CD1 4.21Å; L511-L569 PolarHBondContact N-O 2.93Å; L511-L569 PolarHBondContact O-N 3.47Å; L511-I571 HydrophobicContact CB-CD1 3.98Å; L511-I571 HydrophobicContact CD2-CD1 4.33Å
512V98.1Very high92.8Very high0 Ų051.9 Ų51.90%030%0.298CS..EExtended strand (participates in β ladder)trans-102.1128.9176.4-176.60000107.7L371 F480 A499 F500 L514 V568L371-V512 HydrophobicContact CB-CG2 4.01Å; L371-V512 HydrophobicContact CD1-CB 4.48Å; L371-V512 HydrophobicContact CD1-CG1 3.93Å; L371-V512 HydrophobicContact CD1-CG2 3.66Å; L371-V512 HydrophobicContact CG-CG2 4.49Å; F480-V512 HydrophobicContact CE1-CG2 4.2Å; F480-V512 HydrophobicContact CZ-CG2 4.46Å; A499-V512 CarbonylContact C-O 3.49Å; A499-V512 VanDerWaalsContact CA-O 3.24Å; A499-V512 WeakPolarHBondContact CA-O 3.34Å; F500-V512 HydrophobicContact CD1-CB 4.2Å; F500-V512 HydrophobicContact CD1-CG1 4.5Å; F500-V512 HydrophobicContact CD2-CB 4.23Å; F500-V512 HydrophobicContact CD2-CG2 4.34Å; F500-V512 HydrophobicContact CE1-CB 3.79Å; F500-V512 HydrophobicContact CE1-CG1 3.74Å; F500-V512 HydrophobicContact CE1-CG2 4.48Å; F500-V512 HydrophobicContact CE2-CB 3.8Å; F500-V512 HydrophobicContact CE2-CG1 4.4Å; F500-V512 HydrophobicContact CE2-CG2 3.67Å; F500-V512 HydrophobicContact CG-CB 4.42Å; F500-V512 HydrophobicContact CZ-CB 3.59Å; F500-V512 HydrophobicContact CZ-CG1 3.7Å; F500-V512 HydrophobicContact CZ-CG2 3.78Å; F500-V512 PolarHBondContact N-O 2.88Å; F500-V512 PolarHBondContact O-N 2.88Å; V512-L514 HydrophobicContact CG1-CD2 3.89Å; V512-L514 HydrophobicContact CG1-CG 4.18Å; V512-V568 HydrophobicContact CG2-CG1 4.41Å
513V98Very high92.6Very high0 Ų058 Ų580%033%0.33CS..EExtended strand (participates in β ladder)trans-129.7120.4-178-164.70000108.7V497 A499 L511 I526 L528 L561 L567 L569V497-V513 HydrophobicContact CG1-CG1 3.91Å; A499-V513 HydrophobicContact CB-CG1 4.32Å; L511-V513 HydrophobicContact CD1-CG2 4.46Å; L511-V513 HydrophobicContact CD2-CG2 4.35Å; L511-V513 HydrophobicContact CG-CG2 3.91Å; V513-I526 HydrophobicContact CG1-CD1 3.69Å; V513-L528 HydrophobicContact CG1-CD1 4.28Å; V513-L528 HydrophobicContact CG2-CD1 3.46Å; V513-L528 VanDerWaalsContact CG2-CD1 3.46Å; V513-L561 HydrophobicContact CG1-CD1 3.71Å; V513-L567 HydrophobicContact CB-CB 4.25Å; V513-L567 PolarHBondContact N-O 3.32Å; V513-L567 PolarHBondContact O-N 2.9Å; V513-L569 HydrophobicContact CG2-CD1 4.44Å
514L97.4Very high92.6Very high0 Ų056.3 Ų56.30%032%0.324CS..EExtended strand (participates in β ladder)trans-118.6121-177-51.5179.7000108.4V364 A367 L368 V497 L498 V512 L516 Q565 V566V364-L514 HydrophobicContact CG1-CB 4.08Å; V364-L514 HydrophobicContact CG1-CD1 4.34Å; A367-L514 HydrophobicContact CB-CD2 3.67Å; L368-L514 HydrophobicContact CB-CD1 3.77Å; L368-L514 HydrophobicContact CD1-CD1 3.85Å; L368-L514 HydrophobicContact CG-CD1 4.35Å; V497-L514 CarbonylContact C-O 3.58Å; V497-L514 WeakPolarHBondContact CA-O 3.24Å; L498-L514 HydrophobicContact CB-CB 4.34Å; L498-L514 PolarHBondContact N-O 2.84Å; L498-L514 PolarHBondContact O-N 3.01Å; V512-L514 HydrophobicContact CG1-CD2 3.89Å; V512-L514 HydrophobicContact CG1-CG 4.18Å; L514-L516 HydrophobicContact CB-CD1 3.76Å; L514-L516 WeakPolarHBondContact O-CD1 3.42Å; L514-Q565 WeakPolarHBondContact CA-O 3.13Å; L514-V566 HydrophobicContact CD2-CB 4.25Å; L514-V566 HydrophobicContact CD2-CG1 3.91Å; L514-V566 HydrophobicContact CD2-CG2 3.97Å
515N96Very high92.6Very high0 Ų061.6 Ų61.60%035%0.346CS..EExtended strand (participates in β ladder)trans-95.8111.3165.2-171.34.9000109.2T496 A517 L561 G562 P564 Q565T496-N515 WeakPolarHBondContact CB-OD1 3.43Å; T496-N515 PolarHBondContact O-OD1 2.96Å; T496-N515 PolarHBondContact OG1-OD1 3.37Å; N515-A517 VanDerWaalsContact C-N 3.29Å; N515-A517 VanDerWaalsContact OD1-CB 3.28Å; N515-A517 WeakPolarHBondContact OD1-CB 3.37Å; N515-A517 PolarHBondContact OD1-N 3.36Å; N515-A517 VanDerWaalsContact OD1-N 3.09Å; N515-L561 HydrophobicContact CB-CD1 4.3Å; N515-G562 WeakPolarHBondContact CB-O 3.48Å; N515-G562 PolarHBondContact ND2-O 3.35Å; N515-P564 VanDerWaalsContact O-CA 3.26Å; N515-P564 WeakPolarHBondContact O-CA 3.49Å; N515-Q565 PolarHBondContact N-O 2.99Å; N515-Q565 PolarHBondContact O-N 2.8Å
516L94.1Very high92.8Very high24 Ų2454.2 Ų54.213%0.12631%0.306CS..  trans-88.17.9-179.7-69.777.3000112.4W314 L323 F361 V364 T496 L498 L514W314-L516 HydrophobicContact CH2-CD2 4.49Å; W314-L516 HydrophobicContact CZ2-CD2 3.66Å; W314-L516 HydrophobicContact CZ2-CG 4.39Å; L323-L516 HydrophobicContact CD1-CD2 3.31Å; F361-L516 WeakPolarHBondContact CE1-O 3.15Å; V364-L516 HydrophobicContact CG1-CD1 4.26Å; V364-L516 HydrophobicContact CG1-CG 4.01Å; T496-L516 PolarHBondContact O-N 3.15Å; L498-L516 HydrophobicContact CB-CD1 3.77Å; L514-L516 HydrophobicContact CB-CD1 3.76Å; L514-L516 WeakPolarHBondContact O-CD1 3.42Å
517A92Very high92.9Very high11 Ų1154 Ų549%0.09128%0.284CS..PPolyproline II helixtrans-67.3147.8175.100000111.6T496 N515 A521 P564T496-A517 HydrophobicContact CG2-CB 3.95Å; N515-A517 VanDerWaalsContact C-N 3.29Å; N515-A517 VanDerWaalsContact OD1-CB 3.28Å; N515-A517 WeakPolarHBondContact OD1-CB 3.37Å; N515-A517 PolarHBondContact OD1-N 3.36Å; N515-A517 VanDerWaalsContact OD1-N 3.09Å; A517-A521 HydrophobicContact CB-CB 3.67Å; A517-P564 WeakPolarHBondContact O-CA 3.46Å
518S87.1Confident92.8Very high74 Ų7448.9 Ų48.952%0.51726%0.262SS..PPolyproline II helixtrans-60157.4175.660.90000112.3R520 A521 S563S518-R520 PolarHBondContact O-N 3.09Å; S518-A521 PolarHBondContact O-N 3.43Å; S518-S563 WeakPolarHBondContact O-CB 3.49Å; S518-S563 PolarHBondContact O-OG 3.35Å; S518-S563 VanDerWaalsContact O-OG 3.09Å
519S81.3Confident92.7Very high58 Ų5849.5 Ų49.541%0.40626%0.264SS..THydrogen-bonded Turntrans-53.9136.1172.5-57.70000110.4P564S519-P564 WeakPolarHBondContact OG-CD 3.37Å
520R82.4Confident92.5Very high249 Ų24951.7 Ų51.794%0.9428%0.28SS*.THydrogen-bonded Turntrans81.66.3-176.3-46.6169.6-179.2178.90116.8S518S518-R520 PolarHBondContact O-N 3.09Å
521A86.9Confident92.2Very high30 Ų3051.6 Ų51.625%0.24828%0.28CS..PPolyproline II helixtrans-62.3151.6167.200000110.7A517 S518 S563A517-A521 HydrophobicContact CB-CB 3.67Å; S518-A521 PolarHBondContact O-N 3.43Å; A521-S563 WeakPolarHBondContact CB-OG 3.32Å; A521-S563 PolarHBondContact N-OG 3.35Å; A521-S563 PolarHBondContact O-OG 2.92Å
522P90Very high91.7Very high101 Ų10153.9 Ų53.966%0.65629%0.293SS*.PPolyproline II helixtrans-63.1154.9178.926.5-34.6000111.5L524P522-L524 PolarHBondContact O-N 3.25Å
523L92.7Very high91Very high128 Ų12863.1 Ų63.167%0.6734%0.336SS*.PPolyproline II helixtrans-58.5133.2172.1-66.6176.6000110.1T560 L561L523-T560 HydrophobicContact CB-CG2 4.02Å; L523-T560 HydrophobicContact CD1-CG2 4.08Å; L523-T560 HydrophobicContact CD2-CG2 4.28Å; L523-T560 HydrophobicContact CG-CG2 4.36Å; L523-L561 CarbonylContact C-O 3.56Å; L523-L561 VanDerWaalsContact CA-O 3.31Å; L523-L561 WeakPolarHBondContact CA-O 3.39Å
524L93.7Very high90.4Very high37 Ų3770.1 Ų70.119%0.19437%0.368CS..EExtended strand (participates in β ladder)trans-99.3136.4175.6-60.5178.7000109.6Q494 V497 P522 I526 T560 L561Q494-L524 HydrophobicContact CB-CD1 4.29Å; Q494-L524 HydrophobicContact CG-CD1 4.32Å; Q494-L524 HydrophobicContact CG-CD2 4.49Å; V497-L524 HydrophobicContact CG2-CD1 3.85Å; P522-L524 PolarHBondContact O-N 3.25Å; L524-I526 HydrophobicContact CB-CG2 4.3Å; L524-T560 CarbonylContact O-C 3.27Å; L524-T560 VanDerWaalsContact O-CA 3.25Å; L524-T560 WeakPolarHBondContact O-CA 3.43Å; L524-L561 HydrophobicContact CB-CB 4.48Å; L524-L561 PolarHBondContact N-O 2.88Å; L524-L561 PolarHBondContact O-N 3.16Å
525K93.5Very high90Very high153 Ų15370.3 Ų70.367%0.66537%0.37SS*.EExtended strand (participates in β ladder)trans-97.2127.9161.8-72.2-171.1179.5-175.30108.8Q494 I559Q494-K525 PolarHBondContact NE2-O 2.72Å; K525-I559 CarbonylContact C-O 3.51Å; K525-I559 WeakPolarHBondContact CA-O 3.39Å
526I94.5Very high89.8Confident4 Ų476.4 Ų76.42%0.02140%0.398CS..EExtended strand (participates in β ladder)trans-126.8146.4-17965.6169.3000110.8Q494 V497 V513 L524 L528 I559 L561Q494-I526 HydrophobicContact CG-CG2 4.22Å; V497-I526 HydrophobicContact CG2-CG2 4.35Å; V513-I526 HydrophobicContact CG1-CD1 3.69Å; L524-I526 HydrophobicContact CB-CG2 4.3Å; I526-L528 HydrophobicContact CD1-CD1 3.7Å; I526-L528 HydrophobicContact CD1-CD2 3.98Å; I526-L528 HydrophobicContact CD1-CG 3.81Å; I526-L528 HydrophobicContact CG1-CD1 4.42Å; I526-L528 HydrophobicContact CG1-CG 4.2Å; I526-I559 HydrophobicContact CD1-CB 4.41Å; I526-I559 HydrophobicContact CD1-CG2 4.3Å; I526-I559 HydrophobicContact CG1-CB 3.85Å; I526-I559 HydrophobicContact CG1-CG2 4.14Å; I526-I559 PolarHBondContact N-O 2.9Å; I526-I559 PolarHBondContact O-N 3.46Å; I526-L561 HydrophobicContact CD1-CD1 3.41Å; I526-L561 VanDerWaalsContact CD1-CD1 3.41Å; I526-L561 HydrophobicContact CD1-CG 3.93Å; I526-L561 HydrophobicContact CG1-CD1 4.26Å; I526-L561 HydrophobicContact CG1-CG 4.39Å; I526-L561 HydrophobicContact CG2-CD1 4.47Å
527D94.2Very high89.9Confident83 Ų8380.8 Ų80.844%0.44441%0.414SS..  trans-107.2118.4172.4-175.2-14.2000108.1S529 N557D527-S529 WeakPolarHBondContact OD1-CB 3.08Å; D527-S529 PolarHBondContact OD1-N 3.36Å; D527-S529 PolarHBondContact OD1-OG 3.18Å; D527-N557 WeakPolarHBondContact OD1-CA 3.27Å
528L94.1Very high90Very high0 Ų080.2 Ų80.20%041%0.41CS..  trans-114.114.5179.9-62.9179.5000112.2I490 A499 L511 V513 I526 S530 V531 L556 I559 L569I490-L528 HydrophobicContact CG2-CD2 4.35Å; A499-L528 HydrophobicContact CB-CD2 4.28Å; L511-L528 HydrophobicContact CD2-CB 3.9Å; L511-L528 HydrophobicContact CD2-CD1 3.63Å; L511-L528 HydrophobicContact CD2-CG 4.27Å; L511-L528 HydrophobicContact CG-CD1 4.45Å; V513-L528 HydrophobicContact CG1-CD1 4.28Å; V513-L528 HydrophobicContact CG2-CD1 3.46Å; V513-L528 VanDerWaalsContact CG2-CD1 3.46Å; I526-L528 HydrophobicContact CD1-CD1 3.7Å; I526-L528 HydrophobicContact CD1-CD2 3.98Å; I526-L528 HydrophobicContact CD1-CG 3.81Å; I526-L528 HydrophobicContact CG1-CD1 4.42Å; I526-L528 HydrophobicContact CG1-CG 4.2Å; L528-S530 PolarHBondContact O-N 3.46Å; L528-S530 VanDerWaalsContact O-N 3.15Å; L528-V531 WeakPolarHBondContact O-CB 3.26Å; L528-V531 WeakPolarHBondContact O-CG1 3.32Å; L528-V531 PolarHBondContact O-N 3Å; L528-L556 HydrophobicContact CB-CD2 4.22Å; L528-L556 PolarHBondContact N-O 3.16Å; L528-I559 HydrophobicContact CB-CD1 4.34Å; L528-I559 HydrophobicContact CD1-CD1 3.51Å; L528-I559 HydrophobicContact CG-CD1 4.17Å; L528-L569 HydrophobicContact CD1-CD1 4.32Å
529S91.6Very high90.5Very high50 Ų5078.8 Ų78.835%0.3540%0.395SS..G310 helixtrans-61.1-21.5179.958.80000113.3D527 V531 D532D527-S529 WeakPolarHBondContact OD1-CB 3.08Å; D527-S529 PolarHBondContact OD1-N 3.36Å; D527-S529 PolarHBondContact OD1-OG 3.18Å; S529-V531 PolarHBondContact O-N 3.36Å; S529-D532 CarbonylContact O-C 3.47Å; S529-D532 PolarHBondContact O-N 2.98Å
530S90.4Very high91.2Very high74 Ų7476.1 Ų76.152%0.51738%0.376SS..G310 helixtrans-68.7-9.8176.967.40000114.7I490 L528 D532I490-S530 WeakPolarHBondContact CG2-OG 3.34Å; L528-S530 PolarHBondContact O-N 3.46Å; L528-S530 VanDerWaalsContact O-N 3.15Å; S530-D532 VanDerWaalsContact C-N 3.26Å; S530-D532 PolarHBondContact O-N 3.04Å
531V89.9Confident91.9Very high7 Ų765.4 Ų65.44%0.04234%0.338CS..G310 helixtrans-64.5-32.9176.969.90000112.8I490 K503 L511 L528 S529 L556 I571I490-V531 HydrophobicContact CD1-CB 4.18Å; I490-V531 HydrophobicContact CD1-CG2 3.99Å; I490-V531 HydrophobicContact CG1-CB 4.45Å; I490-V531 HydrophobicContact CG1-CG2 4.29Å; K503-V531 PolarHBondContact NZ-O 3.48Å; L511-V531 HydrophobicContact CB-CG2 4.46Å; L511-V531 HydrophobicContact CD1-CG2 4.11Å; L511-V531 HydrophobicContact CD2-CB 4.22Å; L511-V531 HydrophobicContact CD2-CG1 4.21Å; L511-V531 HydrophobicContact CD2-CG2 4.22Å; L528-V531 WeakPolarHBondContact O-CB 3.26Å; L528-V531 WeakPolarHBondContact O-CG1 3.32Å; L528-V531 PolarHBondContact O-N 3Å; S529-V531 PolarHBondContact O-N 3.36Å; V531-L556 HydrophobicContact CG1-CD1 3.97Å; V531-I571 HydrophobicContact CG1-CD1 3.84Å; V531-I571 HydrophobicContact CG2-CD1 4.48Å
532D87.3Confident92.4Very high49 Ų4965.1 Ų65.126%0.26233%0.332SS..  trans-164.2106.9-177.6-171.2-30.3000108.1S529 S530 E534 A535S529-D532 CarbonylContact O-C 3.47Å; S529-D532 PolarHBondContact O-N 2.98Å; S530-D532 VanDerWaalsContact C-N 3.26Å; S530-D532 PolarHBondContact O-N 3.04Å; D532-E534 PolarHBondContact O-N 3.47Å; D532-E534 VanDerWaalsContact O-N 3.11Å; D532-E534 WeakPolarHBondContact OD1-CB 3.3Å; D532-E534 PolarHBondContact OD1-N 3.06Å; D532-A535 HydrophobicContact CB-CB 3.82Å; D532-A535 PolarHBondContact O-N 3.18Å; D532-A535 PolarHBondContact OD1-N 3.26Å
533E83.5Confident92.6Very high194 Ų19460.9 Ų60.991%0.90730%0.304SS*.THydrogen-bonded Turntrans-59.1-23.5-179-63.7-177.7177.300112.8
534E85.6Confident92.7Very high146 Ų14655.3 Ų55.368%0.68228%0.275SS*.THydrogen-bonded Turntrans-87.7-14.4177.8-59.8-167.5169.400112.4D532 S574D532-E534 PolarHBondContact O-N 3.47Å; D532-E534 VanDerWaalsContact O-N 3.11Å; D532-E534 WeakPolarHBondContact OD1-CB 3.3Å; D532-E534 PolarHBondContact OD1-N 3.06Å; E534-S574 WeakPolarHBondContact O-CB 3.47Å; E534-S574 PolarHBondContact O-OG 3.12Å
535A89.7Confident92.6Very high4 Ų457.8 Ų57.83%0.03329%0.288CS..  trans-98.4125.7-178.400000112.2D532 L556 I571D532-A535 HydrophobicContact CB-CB 3.82Å; D532-A535 PolarHBondContact O-N 3.18Å; D532-A535 PolarHBondContact OD1-N 3.26Å; A535-L556 HydrophobicContact CB-CD1 4.05Å; A535-I571 HydrophobicContact CB-CG2 3.45Å; A535-I571 VanDerWaalsContact CB-CG2 3.45Å
536Q92.1Very high92.2Very high128 Ų12857.7 Ų57.760%0.59828%0.284SS*.  trans-99.3-22.4176.6-66.4-176.5-7.500113.3L556Q536-L556 PolarHBondContact O-N 2.93Å
537Y94.6Very high91.6Very high116 Ų11661.8 Ų61.846%0.45531%0.31SS..EExtended strand (participates in β ladder)trans-135.2152.6-170.7-62.2-83.9000111.2T553 V554 P555 L572Y537-T553 HydrophobicContact CD1-CG2 3.88Å; Y537-T553 HydrophobicContact CG-CG2 4.02Å; Y537-V554 WeakPolarHBondContact CA-O 3.48Å; Y537-P555 HydrophobicContact CD1-CB 4.27Å; Y537-P555 HydrophobicContact CE1-CB 4.13Å; Y537-L572 PolarHBondContact O-N 2.8Å
538A95.9Very high91.1Very high0 Ų060.1 Ų60.10%030%0.298CS..EExtended strand (participates in β ladder)trans-136.4156.4170.700000110.8T553 V554 L556 L569 K570 I571A538-T553 CarbonylContact O-C 3.58Å; A538-T553 WeakPolarHBondContact O-CA 3.36Å; A538-V554 PolarHBondContact N-O 3.43Å; A538-V554 PolarHBondContact O-N 3.47Å; A538-L556 HydrophobicContact CB-CD2 3.79Å; A538-L556 HydrophobicContact CB-CG 4.18Å; A538-L569 HydrophobicContact CB-CB 3.92Å; A538-L569 HydrophobicContact CB-CD1 4.39Å; A538-K570 CarbonylContact C-O 3.57Å; A538-K570 VanDerWaalsContact CA-O 3.32Å; A538-K570 WeakPolarHBondContact CA-O 3.35Å; A538-K570 WeakPolarHBondContact CB-O 3.48Å; A538-I571 HydrophobicContact CB-CD1 4.1Å
539E96.6Very high90.7Very high44 Ų4466.8 Ų66.821%0.20633%0.333CS..EExtended strand (participates in β ladder)trans-96.5135.1176.4-176.3-176.8118.300110V541 N551 S552 L569 K570 L572E539-V541 PolarHBondContact O-N 2.87Å; E539-N551 HydrophobicContact CG-CB 4.34Å; E539-N551 PolarHBondContact OE1-OD1 3.5Å; E539-S552 WeakPolarHBondContact CA-O 3.39Å; E539-L569 CarbonylContact O-C 3.57Å; E539-L569 VanDerWaalsContact O-CA 3.31Å; E539-L569 WeakPolarHBondContact O-CA 3.46Å; E539-K570 HydrophobicContact CB-CB 4.4Å; E539-K570 PolarHBondContact N-O 3.18Å; E539-K570 PolarHBondContact O-N 3.42Å; E539-L572 HydrophobicContact CB-CD2 4.24Å; E539-L572 HydrophobicContact CB-CG 4.44Å
540I96.7Very high90.6Very high2 Ų271.2 Ų71.21%0.0135%0.346CS..EExtended strand (participates in β ladder)trans-74.3111.4177-58.5-81.4000109D543 Y548 N551 S552 V554 L567 L569I540-D543 HydrophobicContact CG2-CB 4.32Å; I540-Y548 HydrophobicContact CD1-CD1 4.21Å; I540-Y548 HydrophobicContact CD1-CD2 3.99Å; I540-Y548 HydrophobicContact CD1-CG 3.73Å; I540-Y548 HydrophobicContact CG1-CG 4.25Å; I540-N551 WeakPolarHBondContact O-CA 3.17Å; I540-N551 PolarHBondContact O-N 3.42Å; I540-S552 WeakPolarHBondContact CG1-O 3.42Å; I540-S552 PolarHBondContact N-O 3.15Å; I540-V554 HydrophobicContact CD1-CG1 3.88Å; I540-V554 HydrophobicContact CD1-CG2 3.93Å; I540-V554 HydrophobicContact CG1-CG1 3.85Å; I540-V554 HydrophobicContact CG1-CG2 4.27Å; I540-L567 HydrophobicContact CD1-CD1 3.74Å; I540-L567 HydrophobicContact CD1-CD2 4.32Å; I540-L567 HydrophobicContact CD1-CG 4.33Å; I540-L567 HydrophobicContact CG2-CD1 4.44Å; I540-L569 HydrophobicContact CD1-CD2 3.43Å; I540-L569 VanDerWaalsContact CD1-CD2 3.43Å; I540-L569 HydrophobicContact CG1-CD2 4.25Å
541V96.4Very high90.6Very high23 Ų2371.6 Ų71.614%0.13934%0.343CS..EExtended strand (participates in β ladder)trans-101.3-31178.7-171.40000111.3L474 F510 E539 F550 V568 K570L474-V541 HydrophobicContact CD2-CG1 3.42Å; L474-V541 VanDerWaalsContact CD2-CG1 3.42Å; F510-V541 HydrophobicContact CE1-CG2 4.23Å; E539-V541 PolarHBondContact O-N 2.87Å; V541-F550 WeakPolarHBondContact O-CD2 3.39Å; V541-F550 WeakPolarHBondContact O-CE2 3.46Å; V541-V568 PolarHBondContact N-O 2.87Å; V541-K570 HydrophobicContact CG2-CB 3.49Å; V541-K570 VanDerWaalsContact CG2-CB 3.49Å
542H96.8Very high90.8Very high25 Ų2573 Ų7312%0.11635%0.352CS..EExtended strand (participates in β ladder)trans-150.8138.6175-171.264000111.2H467 L474 L567 V568H467-H542 AromaticContact CE1-CD2 3.82Å; H467-H542 AromaticContact CE1-NE2 3.04Å; H467-H542 PolarHBondContact CE1-NE2 3.45Å; H467-H542 AromaticContact CG-NE2 3.89Å; H467-H542 AromaticContact ND1-CE1 3.59Å; H467-H542 AromaticContact ND1-NE2 2.91Å; H467-H542 PolarHBondContact ND1-NE2 3.14Å; L474-H542 HydrophobicContact CD1-CB 3.93Å; H542-L567 CarbonylContact O-C 3.49Å; H542-L567 WeakPolarHBondContact O-CA 3.33Å; H542-V568 HydrophobicContact CB-CB 3.86Å; H542-V568 HydrophobicContact CB-CG2 3.93Å; H542-V568 PolarHBondContact N-O 3.42Å; H542-V568 VanDerWaalsContact N-O 3.08Å; H542-V568 PolarHBondContact O-N 3.34Å
543D95.5Very high91.2Very high12 Ų1274.5 Ų74.56%0.06436%0.364CS..EExtended strand (participates in β ladder)trans-144.4115176.8-177.1-10.1000109.6I540 L545 R546 P547 Y548 Q565 V566 L567I540-D543 HydrophobicContact CG2-CB 4.32Å; D543-L545 VanDerWaalsContact C-N 3.33Å; D543-L545 PolarHBondContact O-N 2.84Å; D543-L545 PolarHBondContact OD1-N 3.4Å; D543-R546 VanDerWaalsContact CG-N 3.25Å; D543-R546 WeakPolarHBondContact O-CG 3.48Å; D543-R546 PolarHBondContact OD1-N 3.18Å; D543-R546 WeakPolarHBondContact OD2-CA 3.44Å; D543-R546 PolarHBondContact OD2-N 3.12Å; D543-P547 WeakPolarHBondContact OD2-CD 3.49Å; D543-P547 WeakPolarHBondContact OD2-CG 3.32Å; D543-Y548 WeakPolarHBondContact OD2-CD2 3.44Å; D543-Y548 PolarHBondContact OD2-N 2.75Å; D543-Q565 PolarHBondContact OD1-NE2 2.64Å; D543-Q565 PolarHBondContact OD2-NE2 3.07Å; D543-V566 WeakPolarHBondContact CA-O 3.42Å; D543-L567 HydrophobicContact CB-CD1 3.89Å
544S94.4Very high91.8Very high11 Ų1165.8 Ų65.88%0.07732%0.323CS..SBendtrans-68.3-24.8-178.859.70000115.4K363 Q565 V566K363-S544 PolarHBondContact NZ-O 2.94Å; S544-Q565 WeakPolarHBondContact OG-CA 3.47Å; S544-V566 PolarHBondContact N-O 2.88Å; S544-V566 PolarHBondContact OG-N 3.04Å; S544-V566 PolarHBondContact OG-O 3.1Å
545L90.5Very high92.2Very high89 Ų8961.2 Ų61.247%0.46631%0.306SS..SBendtrans-103.9-16.5-180-66.1-175.2000112.3D543 P547 Q565D543-L545 VanDerWaalsContact C-N 3.33Å; D543-L545 PolarHBondContact O-N 2.84Å; D543-L545 PolarHBondContact OD1-N 3.4Å; L545-P547 WeakPolarHBondContact O-CD 3.4Å; L545-Q565 HydrophobicContact CB-CG 4.24Å; L545-Q565 HydrophobicContact CD1-CB 3.74Å; L545-Q565 HydrophobicContact CD1-CG 3.91Å; L545-Q565 HydrophobicContact CG-CB 4.07Å; L545-Q565 HydrophobicContact CG-CG 3.88Å
546R85.4Confident92.4Very high151 Ų15161 Ų6157%0.5731%0.305SS*.  trans57.132.1179.9-50.8-178.4-178.5-168.40.2117.1P461 D543 Y548P461-R546 PolarHBondContact O-NH2 2.98Å; D543-R546 VanDerWaalsContact CG-N 3.25Å; D543-R546 WeakPolarHBondContact O-CG 3.48Å; D543-R546 PolarHBondContact OD1-N 3.18Å; D543-R546 WeakPolarHBondContact OD2-CA 3.44Å; D543-R546 PolarHBondContact OD2-N 3.12Å; R546-Y548 PolarHBondContact O-N 3.18Å
547P81.3Confident92.5Very high89 Ų8959.8 Ų59.858%0.57830%0.302SS*.SBendtrans-62.3-27.416326.7-37.4000112.5D543 L545D543-P547 WeakPolarHBondContact OD2-CD 3.49Å; D543-P547 WeakPolarHBondContact OD2-CG 3.32Å; L545-P547 WeakPolarHBondContact O-CD 3.4Å
548Y84.5Confident92.3Very high49 Ų4957 Ų5719%0.19230%0.3CS..SBendtrans-95.4143.1177.5-63.2-73.3000112I540 D543 R546 V554 T560 L567I540-Y548 HydrophobicContact CD1-CD1 4.21Å; I540-Y548 HydrophobicContact CD1-CD2 3.99Å; I540-Y548 HydrophobicContact CD1-CG 3.73Å; I540-Y548 HydrophobicContact CG1-CG 4.25Å; D543-Y548 WeakPolarHBondContact OD2-CD2 3.44Å; D543-Y548 PolarHBondContact OD2-N 2.75Å; R546-Y548 PolarHBondContact O-N 3.18Å; Y548-V554 HydrophobicContact CD1-CG1 3.79Å; Y548-V554 HydrophobicContact CE1-CG1 3.85Å; Y548-T560 WeakPolarHBondContact CE2-O 3.4Å; Y548-T560 WeakPolarHBondContact OH-CA 2.78Å; Y548-T560 PolarHBondContact OH-N 2.86Å; Y548-T560 PolarHBondContact OH-O 3.26Å; Y548-T560 VanDerWaalsContact OH-O 3.05Å; Y548-L567 HydrophobicContact CD2-CD1 3.99Å; Y548-L567 HydrophobicContact CE2-CD1 4.5Å
549L85.9Confident92.3Very high140 Ų14057 Ų5773%0.73330%0.3SS*.PPolyproline II helixtrans-72.7135.8170.6-66.4173.8000109.6N551 S552L549-N551 PolarHBondContact O-N 3.14Å; L549-S552 VanDerWaalsContact O-CB 3.23Å; L549-S552 WeakPolarHBondContact O-CB 3.2Å; L549-S552 PolarHBondContact O-N 3.38Å; L549-S552 PolarHBondContact O-OG 3.14Å
550F89Confident92.2Very high143 Ų14357 Ų5763%0.62730%0.303SS*.THydrogen-bonded Turntrans-55.8138.4171.8179.5-103.6000110.6V541 S552V541-F550 WeakPolarHBondContact O-CD2 3.39Å; V541-F550 WeakPolarHBondContact O-CE2 3.46Å; F550-S552 PolarHBondContact O-N 2.73Å; F550-S552 VanDerWaalsContact O-N 3.16Å
551N91.6Very high92.1Very high82 Ų8256.9 Ų56.944%0.43930%0.303SS..THydrogen-bonded Turntrans60.49.8-172.9-61-10.5000115.9E539 I540 L549E539-N551 HydrophobicContact CG-CB 4.34Å; E539-N551 PolarHBondContact OE1-OD1 3.5Å; I540-N551 WeakPolarHBondContact O-CA 3.17Å; I540-N551 PolarHBondContact O-N 3.42Å; L549-N551 PolarHBondContact O-N 3.14Å
552S94.4Very high92Very high35 Ų3556.3 Ų56.325%0.24530%0.301CS..  trans-71.3146.3170.465.20000110.9E539 I540 L549 F550E539-S552 WeakPolarHBondContact CA-O 3.39Å; I540-S552 WeakPolarHBondContact CG1-O 3.42Å; I540-S552 PolarHBondContact N-O 3.15Å; L549-S552 VanDerWaalsContact O-CB 3.23Å; L549-S552 WeakPolarHBondContact O-CB 3.2Å; L549-S552 PolarHBondContact O-N 3.38Å; L549-S552 PolarHBondContact O-OG 3.14Å; F550-S552 PolarHBondContact O-N 2.73Å; F550-S552 VanDerWaalsContact O-N 3.16Å
553T95.2Very high91.8Very high82 Ų8255.9 Ų55.950%0.50330%0.301SS..EExtended strand (participates in β ladder)trans-89.8130.3175.9-55.90000109.8Y537 A538 L572Y537-T553 HydrophobicContact CD1-CG2 3.88Å; Y537-T553 HydrophobicContact CG-CG2 4.02Å; A538-T553 CarbonylContact O-C 3.58Å; A538-T553 WeakPolarHBondContact O-CA 3.36Å; T553-L572 HydrophobicContact CG2-CD1 3.93Å
554V94.9Very high91.7Very high10 Ų1055.9 Ų55.96%0.06130%0.301CS..EExtended strand (participates in β ladder)trans-121.6145.9177.3-63.60000110.9Y537 A538 I540 Y548 I559 L569Y537-V554 WeakPolarHBondContact CA-O 3.48Å; A538-V554 PolarHBondContact N-O 3.43Å; A538-V554 PolarHBondContact O-N 3.47Å; I540-V554 HydrophobicContact CD1-CG1 3.88Å; I540-V554 HydrophobicContact CD1-CG2 3.93Å; I540-V554 HydrophobicContact CG1-CG1 3.85Å; I540-V554 HydrophobicContact CG1-CG2 4.27Å; Y548-V554 HydrophobicContact CD1-CG1 3.79Å; Y548-V554 HydrophobicContact CE1-CG1 3.85Å; V554-I559 HydrophobicContact CG2-CG1 4.39Å; V554-L569 HydrophobicContact CG2-CD2 4.05Å
555P94.8Very high91.8Very high50 Ų5055.4 Ų55.433%0.32530%0.298SS..EExtended strand (participates in β ladder)trans-74133.2172.931.7-34.2000110.4Y537 N557 S558Y537-P555 HydrophobicContact CD1-CB 4.27Å; Y537-P555 HydrophobicContact CE1-CB 4.13Å; P555-N557 VanDerWaalsContact C-N 3.26Å; P555-N557 PolarHBondContact O-N 3.18Å; P555-S558 PolarHBondContact O-N 3.46Å
556L94.5Very high92.1Very high1 Ų151.1 Ų51.11%0.00528%0.276CS..THydrogen-bonded Turntrans-67.7-25.3-177.2-77.3169.8000113.3L511 L528 V531 A535 Q536 A538 S558 I559 L569 I571L511-L556 HydrophobicContact CD2-CD2 4.2Å; L528-L556 HydrophobicContact CB-CD2 4.22Å; L528-L556 PolarHBondContact N-O 3.16Å; V531-L556 HydrophobicContact CG1-CD1 3.97Å; A535-L556 HydrophobicContact CB-CD1 4.05Å; Q536-L556 PolarHBondContact O-N 2.93Å; A538-L556 HydrophobicContact CB-CD2 3.79Å; A538-L556 HydrophobicContact CB-CG 4.18Å; L556-S558 VanDerWaalsContact C-N 3.3Å; L556-S558 PolarHBondContact O-N 3.12Å; L556-I559 HydrophobicContact CD2-CD1 4.26Å; L556-L569 HydrophobicContact CD2-CD1 4.3Å; L556-I571 HydrophobicContact CD1-CD1 4.14Å; L556-I571 HydrophobicContact CD2-CD1 4.12Å
557N93.3Very high92.6Very high101 Ų10144 Ų4454%0.5425%0.248SC..THydrogen-bonded Turntrans-80.1-4.9-177.568.1-4000114.9D527 P555D527-N557 WeakPolarHBondContact OD1-CA 3.27Å; P555-N557 VanDerWaalsContact C-N 3.26Å; P555-N557 PolarHBondContact O-N 3.18Å
558S91.8Very high93.4Very high57 Ų5739.7 Ų39.740%0.39922%0.221SC..  trans-154.772.5-177.4175.20000111.2P555 L556P555-S558 PolarHBondContact O-N 3.46Å; L556-S558 VanDerWaalsContact C-N 3.3Å; L556-S558 PolarHBondContact O-N 3.12Å
559I94.7Very high94.1Very high1 Ų137.4 Ų37.41%0.00521%0.212CC..EExtended strand (participates in β ladder)trans-94.9139.4172.2-68.3159.3000109.3K525 I526 L528 V554 L556 L561 L567 L569K525-I559 CarbonylContact C-O 3.51Å; K525-I559 WeakPolarHBondContact CA-O 3.39Å; I526-I559 HydrophobicContact CD1-CB 4.41Å; I526-I559 HydrophobicContact CD1-CG2 4.3Å; I526-I559 HydrophobicContact CG1-CB 3.85Å; I526-I559 HydrophobicContact CG1-CG2 4.14Å; I526-I559 PolarHBondContact N-O 2.9Å; I526-I559 PolarHBondContact O-N 3.46Å; L528-I559 HydrophobicContact CB-CD1 4.34Å; L528-I559 HydrophobicContact CD1-CD1 3.51Å; L528-I559 HydrophobicContact CG-CD1 4.17Å; V554-I559 HydrophobicContact CG2-CG1 4.39Å; L556-I559 HydrophobicContact CD2-CD1 4.26Å; I559-L561 HydrophobicContact CG2-CD2 4.05Å; I559-L561 HydrophobicContact CG2-CG 4.3Å; I559-L567 HydrophobicContact CG2-CD2 3.69Å; I559-L569 HydrophobicContact CD1-CD1 3.6Å
560T94.7Very high94.6Very high44 Ų4434.1 Ų34.127%0.2719%0.192SC..EExtended strand (participates in β ladder)trans-106.3124.8176.5-57.40000109.5L523 L524 Y548L523-T560 HydrophobicContact CB-CG2 4.02Å; L523-T560 HydrophobicContact CD1-CG2 4.08Å; L523-T560 HydrophobicContact CD2-CG2 4.28Å; L523-T560 HydrophobicContact CG-CG2 4.36Å; L524-T560 CarbonylContact O-C 3.27Å; L524-T560 VanDerWaalsContact O-CA 3.25Å; L524-T560 WeakPolarHBondContact O-CA 3.43Å; Y548-T560 WeakPolarHBondContact CE2-O 3.4Å; Y548-T560 WeakPolarHBondContact OH-CA 2.78Å; Y548-T560 PolarHBondContact OH-N 2.86Å; Y548-T560 PolarHBondContact OH-O 3.26Å; Y548-T560 VanDerWaalsContact OH-O 3.05Å
561L94.4Very high94.9Very high0 Ų027.8 Ų27.80%016%0.164CC..EExtended strand (participates in β ladder)trans-115.4133.5179.2-64.9-179000111.8V497 V513 N515 L523 L524 I526 I559 Q565 L567V497-L561 HydrophobicContact CG2-CD1 4.33Å; V513-L561 HydrophobicContact CG1-CD1 3.71Å; N515-L561 HydrophobicContact CB-CD1 4.3Å; L523-L561 CarbonylContact C-O 3.56Å; L523-L561 VanDerWaalsContact CA-O 3.31Å; L523-L561 WeakPolarHBondContact CA-O 3.39Å; L524-L561 HydrophobicContact CB-CB 4.48Å; L524-L561 PolarHBondContact N-O 2.88Å; L524-L561 PolarHBondContact O-N 3.16Å; I526-L561 HydrophobicContact CD1-CD1 3.41Å; I526-L561 VanDerWaalsContact CD1-CD1 3.41Å; I526-L561 HydrophobicContact CD1-CG 3.93Å; I526-L561 HydrophobicContact CG1-CD1 4.26Å; I526-L561 HydrophobicContact CG1-CG 4.39Å; I526-L561 HydrophobicContact CG2-CD1 4.47Å; I559-L561 HydrophobicContact CG2-CD2 4.05Å; I559-L561 HydrophobicContact CG2-CG 4.3Å; L561-Q565 VanDerWaalsContact CA-OE1 3.27Å; L561-L567 HydrophobicContact CD2-CB 4.18Å; L561-L567 HydrophobicContact CD2-CD2 3.97Å
562G94.2Very high94.9Very high10 Ų1026.2 Ų26.210%0.10316%0.156CC..  trans-84.2-169.316000000112.4N515 Q565N515-G562 WeakPolarHBondContact CB-O 3.48Å; N515-G562 PolarHBondContact ND2-O 3.35Å; G562-Q565 WeakPolarHBondContact O-CB 3.31Å
563S92.6Very high94.3Very high16 Ų1629.9 Ų29.911%0.11218%0.179CC..SBendtrans-148.7136.7-16961.10000114.4S518 A521S518-S563 WeakPolarHBondContact O-CB 3.49Å; S518-S563 PolarHBondContact O-OG 3.35Å; S518-S563 VanDerWaalsContact O-OG 3.09Å; A521-S563 WeakPolarHBondContact CB-OG 3.32Å; A521-S563 PolarHBondContact N-OG 3.35Å; A521-S563 PolarHBondContact O-OG 2.92Å
564P93.6Very high93.3Very high12 Ų1228.6 Ų28.68%0.07817%0.173CC..SBendcis-63.7144.9-2528.3-33.7000110S360 F361 V364 N515 A517 S519S360-P564 VanDerWaalsContact O-CG 3.31Å; S360-P564 WeakPolarHBondContact O-CG 3.42Å; F361-P564 HydrophobicContact CD1-CB 4Å; F361-P564 HydrophobicContact CD1-CG 4.24Å; F361-P564 HydrophobicContact CE1-CB 4.09Å; F361-P564 HydrophobicContact CE1-CG 4.4Å; V364-P564 HydrophobicContact CG2-CB 3.88Å; N515-P564 VanDerWaalsContact O-CA 3.26Å; N515-P564 WeakPolarHBondContact O-CA 3.49Å; A517-P564 WeakPolarHBondContact O-CA 3.46Å; S519-P564 WeakPolarHBondContact OG-CD 3.37Å
565Q95.6Very high91.5Very high1 Ų140.2 Ų40.21%0.00522%0.216CC..EExtended strand (participates in β ladder)trans-141.1138.7-179.7-171.6177.411.800111.5L514 N515 D543 S544 L545 L561 G562L514-Q565 WeakPolarHBondContact CA-O 3.13Å; N515-Q565 PolarHBondContact N-O 2.99Å; N515-Q565 PolarHBondContact O-N 2.8Å; D543-Q565 PolarHBondContact OD1-NE2 2.64Å; D543-Q565 PolarHBondContact OD2-NE2 3.07Å; S544-Q565 WeakPolarHBondContact OG-CA 3.47Å; L545-Q565 HydrophobicContact CB-CG 4.24Å; L545-Q565 HydrophobicContact CD1-CB 3.74Å; L545-Q565 HydrophobicContact CD1-CG 3.91Å; L545-Q565 HydrophobicContact CG-CB 4.07Å; L545-Q565 HydrophobicContact CG-CG 3.88Å; L561-Q565 VanDerWaalsContact CA-OE1 3.27Å; G562-Q565 WeakPolarHBondContact O-CB 3.31Å
566V97Very high89Confident0 Ų046.4 Ų46.40%024%0.242CC..EExtended strand (participates in β ladder)trans-102.4129.3163.3-177.80000108.8K363 V364 A367 L514 D543 S544 V568K363-V566 HydrophobicContact CB-CG2 4.29Å; K363-V566 VanDerWaalsContact O-CG2 3.29Å; K363-V566 WeakPolarHBondContact O-CG2 3.1Å; V364-V566 HydrophobicContact CB-CG2 4.42Å; V364-V566 HydrophobicContact CG2-CG2 3.9Å; A367-V566 HydrophobicContact CB-CB 4.17Å; A367-V566 HydrophobicContact CB-CG1 3.45Å; A367-V566 VanDerWaalsContact CB-CG1 3.45Å; A367-V566 HydrophobicContact CB-CG2 3.58Å; L514-V566 HydrophobicContact CD2-CB 4.25Å; L514-V566 HydrophobicContact CD2-CG1 3.91Å; L514-V566 HydrophobicContact CD2-CG2 3.97Å; D543-V566 WeakPolarHBondContact CA-O 3.42Å; S544-V566 PolarHBondContact N-O 2.88Å; S544-V566 PolarHBondContact OG-N 3.04Å; S544-V566 PolarHBondContact OG-O 3.1Å; V566-V568 HydrophobicContact CG1-CG2 4.22Å
567L97.3Very high86.3Confident0 Ų057.4 Ų57.40%028%0.284CS..EExtended strand (participates in β ladder)trans-126.6127.8168.6-165.869.8000109V513 I540 H542 D543 Y548 I559 L561 L569V513-L567 HydrophobicContact CB-CB 4.25Å; V513-L567 PolarHBondContact N-O 3.32Å; V513-L567 PolarHBondContact O-N 2.9Å; I540-L567 HydrophobicContact CD1-CD1 3.74Å; I540-L567 HydrophobicContact CD1-CD2 4.32Å; I540-L567 HydrophobicContact CD1-CG 4.33Å; I540-L567 HydrophobicContact CG2-CD1 4.44Å; H542-L567 CarbonylContact O-C 3.49Å; H542-L567 WeakPolarHBondContact O-CA 3.33Å; D543-L567 HydrophobicContact CB-CD1 3.89Å; Y548-L567 HydrophobicContact CD2-CD1 3.99Å; Y548-L567 HydrophobicContact CE2-CD1 4.5Å; I559-L567 HydrophobicContact CG2-CD2 3.69Å; L561-L567 HydrophobicContact CD2-CB 4.18Å; L561-L567 HydrophobicContact CD2-CD2 3.97Å; L567-L569 HydrophobicContact CD2-CD1 4.17Å; L567-L569 HydrophobicContact CD2-CD2 3.95Å; L567-L569 HydrophobicContact CD2-CG 4.15Å; L567-L569 HydrophobicContact CG-CD2 3.98Å; L567-L569 HydrophobicContact CG-CG 4.16Å
568V98Very high83.3Confident0 Ų062.1 Ų62.10%030%0.3CS..EExtended strand (participates in β ladder)trans-117.5124.7171.9-171.40000108.5L371 L474 F480 F510 L511 V512 V541 H542 V566L371-V568 HydrophobicContact CD1-CG2 3.62Å; L474-V568 HydrophobicContact CD1-CB 4.18Å; L474-V568 HydrophobicContact CD1-CG1 4.13Å; L474-V568 HydrophobicContact CD1-CG2 4.04Å; F480-V568 HydrophobicContact CZ-CG1 4.45Å; F510-V568 HydrophobicContact CD1-CG1 4.33Å; L511-V568 WeakPolarHBondContact O-CA 3.35Å; V512-V568 HydrophobicContact CG2-CG1 4.41Å; V541-V568 PolarHBondContact N-O 2.87Å; H542-V568 HydrophobicContact CB-CB 3.86Å; H542-V568 HydrophobicContact CB-CG2 3.93Å; H542-V568 PolarHBondContact N-O 3.42Å; H542-V568 VanDerWaalsContact N-O 3.08Å; H542-V568 PolarHBondContact O-N 3.34Å; V566-V568 HydrophobicContact CG1-CG2 4.22Å
569L97.6Very high80.4Confident0 Ų068.6 Ų68.60%032%0.315CS..EExtended strand (participates in β ladder)trans-116.5139.6-174.9-60.4174.7000109.7F510 L511 V513 L528 A538 E539 I540 V554 L556 I559 L567F510-L569 CarbonylContact C-O 3.58Å; F510-L569 WeakPolarHBondContact CA-O 3.45Å; L511-L569 HydrophobicContact CB-CB 4.25Å; L511-L569 HydrophobicContact CD2-CD1 4.21Å; L511-L569 PolarHBondContact N-O 2.93Å; L511-L569 PolarHBondContact O-N 3.47Å; V513-L569 HydrophobicContact CG2-CD1 4.44Å; L528-L569 HydrophobicContact CD1-CD1 4.32Å; A538-L569 HydrophobicContact CB-CB 3.92Å; A538-L569 HydrophobicContact CB-CD1 4.39Å; E539-L569 CarbonylContact O-C 3.57Å; E539-L569 VanDerWaalsContact O-CA 3.31Å; E539-L569 WeakPolarHBondContact O-CA 3.46Å; I540-L569 HydrophobicContact CD1-CD2 3.43Å; I540-L569 VanDerWaalsContact CD1-CD2 3.43Å; I540-L569 HydrophobicContact CG1-CD2 4.25Å; V554-L569 HydrophobicContact CG2-CD2 4.05Å; L556-L569 HydrophobicContact CD2-CD1 4.3Å; I559-L569 HydrophobicContact CD1-CD1 3.6Å; L567-L569 HydrophobicContact CD2-CD1 4.17Å; L567-L569 HydrophobicContact CD2-CD2 3.95Å; L567-L569 HydrophobicContact CD2-CG 4.15Å; L567-L569 HydrophobicContact CG-CD2 3.98Å; L567-L569 HydrophobicContact CG-CG 4.16Å
570K96.8Very high77.4Confident72 Ų7280.7 Ų80.731%0.31336%0.361SS..EExtended strand (participates in β ladder)trans-98.7119.3166.9173.9-178.5173.9-166.40108.5A508 F510 A538 E539 V541 L572A508-K570 HydrophobicContact CB-CD 4.26Å; A508-K570 HydrophobicContact CB-CG 4.17Å; F510-K570 HydrophobicContact CD1-CB 4.09Å; F510-K570 HydrophobicContact CE1-CB 3.91Å; F510-K570 HydrophobicContact CE1-CG 4.26Å; A538-K570 CarbonylContact C-O 3.57Å; A538-K570 VanDerWaalsContact CA-O 3.32Å; A538-K570 WeakPolarHBondContact CA-O 3.35Å; A538-K570 WeakPolarHBondContact CB-O 3.48Å; E539-K570 HydrophobicContact CB-CB 4.4Å; E539-K570 PolarHBondContact N-O 3.18Å; E539-K570 PolarHBondContact O-N 3.42Å; V541-K570 HydrophobicContact CG2-CB 3.49Å; V541-K570 VanDerWaalsContact CG2-CB 3.49Å; K570-L572 PolarHBondContact O-N 3.05Å
571I95.5Very high74.4Confident10 Ų1087.6 Ų87.65%0.05138%0.383CS..EExtended strand (participates in β ladder)trans-68.5128.7-179.4-56.4-57.3000109T509 L511 V531 A535 A538 L556T509-I571 HydrophobicContact CG2-CB 4.07Å; T509-I571 HydrophobicContact CG2-CG1 3.65Å; T509-I571 PolarHBondContact O-N 3.27Å; L511-I571 HydrophobicContact CB-CD1 3.98Å; L511-I571 HydrophobicContact CD2-CD1 4.33Å; V531-I571 HydrophobicContact CG1-CD1 3.84Å; V531-I571 HydrophobicContact CG2-CD1 4.48Å; A535-I571 HydrophobicContact CB-CG2 3.45Å; A535-I571 VanDerWaalsContact CB-CG2 3.45Å; A538-I571 HydrophobicContact CB-CD1 4.1Å; L556-I571 HydrophobicContact CD1-CD1 4.14Å; L556-I571 HydrophobicContact CD2-CD1 4.12Å
572L91.1Very high71.5Confident49 Ų4990.8 Ų90.826%0.25742%0.416SS..PPolyproline II helixtrans-94.1121.4176-60.9178.2000108.5Y537 E539 T553 K570 S574Y537-L572 PolarHBondContact O-N 2.8Å; E539-L572 HydrophobicContact CB-CD2 4.24Å; E539-L572 HydrophobicContact CB-CG 4.44Å; T553-L572 HydrophobicContact CG2-CD1 3.93Å; K570-L572 PolarHBondContact O-N 3.05Å; L572-S574 PolarHBondContact O-N 3.12Å
573P82.4Confident68.4Low112 Ų11294.9 Ų94.973%0.72745%0.449SS*.PPolyproline II helixtrans-58136.5173.3-19.930.4000109.8R575P573-R575 PolarHBondContact O-N 2.82Å
574S73.6Confident66Low54 Ų54100.1 Ų100.138%0.37848%0.483SS..PPolyproline II helixtrans-54.7133.3165.6-86.50000109.1E534 L572 M576E534-S574 WeakPolarHBondContact O-CB 3.47Å; E534-S574 PolarHBondContact O-OG 3.12Å; L572-S574 PolarHBondContact O-N 3.12Å; S574-M576 PolarHBondContact O-N 3.13Å
575R57.7Low62.9Low254 Ų254105 Ų10596%0.95852%0.517SS*.SBendtrans-41.2114.8177.5-85.6-177.1173.6176.4-1.2108.4P573 R577P573-R575 PolarHBondContact O-N 2.82Å; R575-R577 PolarHBondContact O-N 3.42Å
576M43.3Very low59.6Low181 Ų181109.5 Ų109.589%0.89255%0.548SS*.  trans-35.4133.9-174.4-82.8-165.1-97.500111.9S574 K578S574-M576 PolarHBondContact O-N 3.13Å; M576-K578 PolarHBondContact O-N 3.09Å
577R36.5Very low56.2Low231 Ų231117.5 Ų117.587%0.87259%0.586SS**  trans-13.1109.3153.5-84.9173.1157.9171.3-4.9109.8R575 R579R575-R577 PolarHBondContact O-N 3.42Å; R577-R579 PolarHBondContact O-N 2.64Å
578K31.1Very low53Low201 Ų201128.2 Ų128.287%0.87463%0.626SS**  trans-49.5103.7147.6-88.6-179.1177.2177.60103.5M576 R580M576-K578 PolarHBondContact O-N 3.09Å; K578-R580 PolarHBondContact O-N 2.81Å
579R30.9Very low49.5Very low193 Ų193136.5 Ų136.573%0.72867%0.665SS**  trans-43.4116.4157.9-102-178.4168.7177.9-1.8103.1R577 Y581R577-R579 PolarHBondContact O-N 2.64Å; R579-Y581 HydrophobicContact CB-CD2 3.93Å; R579-Y581 HydrophobicContact CB-CE2 4.02Å; R579-Y581 PolarHBondContact O-N 3.34Å
580R32.1Very low46.1Very low254 Ų254145.6 Ų145.696%0.95871%0.705SS**  trans-59.585.1165.9-81.1-179.3172.4177-2.1105.1K578 G582K578-R580 PolarHBondContact O-N 2.81Å; R580-G582 PolarHBondContact O-N 2.83Å
581Y31.4Very low42.7Very low190 Ų190146.6 Ų146.675%0.74572%0.72SS**  trans-73.675.5148.8-81.7-81.6000104.6R579 A583R579-Y581 HydrophobicContact CB-CD2 3.93Å; R579-Y581 HydrophobicContact CB-CE2 4.02Å; R579-Y581 PolarHBondContact O-N 3.34Å; Y581-A583 PolarHBondContact O-N 3.32Å
582G32.2Very low39.4Very low67 Ų67154.5 Ų154.569%0.69176%0.756SS**  trans-62.1124.5149.200000106.1R580R580-G582 PolarHBondContact O-N 2.83Å
583A29.3Very low36.1Very low95 Ų95159.8 Ų159.879%0.78578%0.78SS**  trans-62.5174-171.800000113.7Y581Y581-A583 PolarHBondContact O-N 3.32Å
584P43.4Very low33.7Very low127 Ų127160.2 Ų160.283%0.82578%0.783SS**  trans-99149.4-152.338.1-33000114.5
585S27Very low31.4Very low114 Ų114164.3 Ų164.380%0.79780%0.8SS**  trans-173.7134156.656.90000105.2
586S26.9Very low30.1Very low95 Ų95156.8 Ų156.866%0.66479%0.787SS**  cis-177148.716.839.70000105.4
587E26.1Very low29.6Very low169 Ų169157 Ų15779%0.7978%0.783SS**  trans63.6122.6145.5-67.6178.1177.200121.3
588R29.5Very low29.1Very low225 Ų225151.7 Ų151.785%0.84978%0.776SS**  trans133.895.9138.5-73.4174.3-172.5-150.40.2109.3
589E24.2Very low29.2Very low173 Ų173150.3 Ų150.381%0.80877%0.772SS**  39.9108.294.2-77.2-171.5159.600111.7
590F26.8Very low29.2Very low192 Ų192148.7 Ų148.784%0.84277%0.773SS**  -173.8130.7119.8-113.2-88.3000112
591C25.9Very low29.4Very low92 Ų92146 Ų14662%0.62277%0.768SS**  trans65.497.8152-85.70000122.2
592Q25.3Very low29.2Very low176 Ų176144.8 Ų144.882%0.82277%0.769SS**  61.8112.5108.5-70.8-176.5-2.400119.2
593Q22.4Very low28.9Very low161 Ų161146.1 Ų146.175%0.75277%0.768SS**  trans-52.2147.1151.1-62.8177.5-6700112.1
594P31.8Very low28.9Very low121 Ų121151 Ų15179%0.78677%0.771SS**  trans-101.8104.5142.722.8-6.9000109.1S596P594-S596 PolarHBondContact O-N 3.01Å
595D25.7Very low28.6Very low140 Ų140158.6 Ų158.675%0.74979%0.792SS**  trans-69.1114.3151.9-86.3-31.3000108
596S31Very low28.7Very low96 Ų96160.8 Ų160.867%0.67179%0.791SS**  trans-153.2108.5153.569.70000113.1P594P594-S596 PolarHBondContact O-N 3.01Å
597K31.3Very low28.8Very low186 Ų186164.3 Ų164.381%0.80980%0.798SS**  trans74.598.4131.7-62.5-176.3179.1179.90118.8
598T27.6Very low28.9Very low119 Ų119164 Ų16473%0.7380%0.798SS**  20.3111.7117.934.20000117.5
599H33.3Very low28.9Very low172 Ų172160.4 Ų160.480%0.79680%0.795SS**  trans-124.897.2145-93.5-72.1000109.2
600H30.4Very low29.2Very low159 Ų159159.6 Ų159.674%0.73680%0.795SS**  trans-67.2125.6153.6-95.1-72.1000108
601F35.5Very low29.3Very low197 Ų197157.5 Ų157.586%0.86479%0.791SS**  trans-117.198.3153-101.4-85.9000107.2
602E28.6Very low29.6Very low164 Ų164162.1 Ų162.177%0.76680%0.804SS**  trans-78.9149.9163.7-84.6-173.5150.800110.9
603S25.4Very low29.9Very low95 Ų95161.1 Ų161.166%0.66480%0.802SS**  trans-28.8141.3168.162.60000118.9
604K29.2Very low30.5Very low197 Ų197161.1 Ų161.186%0.85781%0.806SS**  153.4108.2112-87.8-178.6179.9174.90111.5
605K36.5Very low30.4Very low287 Ų287164.7 Ų164.7100%1.24881%0.808SS**  -1570118.8-109.9-176.8-177.9-179.40109.2

Retrieved 605 of 605 residues in 655.2 ms (Link to these results)