A0A077Z8P6_TRITR Loading...

beta-N-acetylhexosaminidase

AlphaFold DB , UniProt , Accession A0A077Z8P6, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 777 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M48.4Very low47.8Very low33 Ų3381.1 Ų81.116%0.16343%0.43CS..  0-60.70-161.5-179.5-148.200112.9T3 L4 V5 L20 F25 V27 P37 L53M1-T3 VanDerWaalsContact C-N 3.28Å; M1-T3 PolarHBondContact O-N 3Å; M1-L4 WeakPolarHBondContact O-CA 3.43Å; M1-L4 VanDerWaalsContact O-CB 3.32Å; M1-L4 WeakPolarHBondContact O-CB 3.32Å; M1-L4 PolarHBondContact O-N 3.42Å; M1-V5 PolarHBondContact O-N 2.68Å; M1-L20 HydrophobicContact CE-CD2 3.04Å; M1-L20 HydrophobicContact CE-CG 3.9Å; M1-F25 HydrophobicContact SD-CB 4.4Å; M1-V27 HydrophobicContact CE-CG1 3.89Å; M1-P37 HydrophobicContact CG-CB 4.47Å; M1-P37 HydrophobicContact CG-CG 4.02Å; M1-P37 HydrophobicContact SD-CB 4.16Å; M1-P37 HydrophobicContact SD-CG 3.42Å; M1-P37 WeakPolarHBondContact SD-CG 3.24Å; M1-L53 HydrophobicContact CE-CD2 4.1Å
2L47.9Very low48.3Very low23 Ų2376 Ų7612%0.1241%0.406CS..Hα-helixtrans-55.5-37.9178-85.2127.5000113.7L4 K6 T29 N31 P37 E40L2-L4 VanDerWaalsContact C-N 3.28Å; L2-L4 PolarHBondContact O-N 3.06Å; L2-K6 WeakPolarHBondContact O-CB 3.35Å; L2-K6 VanDerWaalsContact O-CG 3.27Å; L2-K6 WeakPolarHBondContact O-CG 3.47Å; L2-K6 PolarHBondContact O-N 3.22Å; L2-T29 WeakPolarHBondContact CD1-O 3.41Å; L2-N31 HydrophobicContact CD1-CB 3.72Å; L2-N31 HydrophobicContact CD2-CB 3.98Å; L2-N31 HydrophobicContact CG-CB 4.34Å; L2-P37 HydrophobicContact CG-CG 4.46Å; L2-E40 HydrophobicContact CD2-CB 4.13Å
3T49.4Very low48.3Very low100 Ų10072.4 Ų72.461%0.61339%0.386SS*.Hα-helixtrans-66.3-28.5174.6-30.70000113.5M1 K6M1-T3 VanDerWaalsContact C-N 3.28Å; M1-T3 PolarHBondContact O-N 3Å; T3-K6 WeakPolarHBondContact O-CB 3.33Å
4L49.7Very low48.7Very low60 Ų6077.4 Ų77.431%0.31441%0.406SS..Hα-helixtrans-79.3-46.2178.1-104.7153.5000110.7M1 L2 K6 R7 S8 F19M1-L4 WeakPolarHBondContact O-CA 3.43Å; M1-L4 VanDerWaalsContact O-CB 3.32Å; M1-L4 WeakPolarHBondContact O-CB 3.32Å; M1-L4 PolarHBondContact O-N 3.42Å; L2-L4 VanDerWaalsContact C-N 3.28Å; L2-L4 PolarHBondContact O-N 3.06Å; L4-K6 PolarHBondContact O-N 2.7Å; L4-R7 PolarHBondContact O-N 3.14Å; L4-S8 PolarHBondContact O-N 2.78Å; L4-F19 HydrophobicContact CD1-CG 4.48Å; L4-F19 HydrophobicContact CD2-CD2 4.34Å; L4-F19 HydrophobicContact CD2-CE2 4.48Å
5V51.3Low49.2Very low0 Ų081.3 Ų81.30%042%0.418CS..Hα-helixtrans-57-34.7168.1176.80000109.9M1 R7 S8 L16 P37 E40 R44 V49M1-V5 PolarHBondContact O-N 2.68Å; V5-R7 PolarHBondContact O-N 2.85Å; V5-S8 PolarHBondContact O-N 3.11Å; V5-S8 PolarHBondContact O-OG 3.3Å; V5-S8 VanDerWaalsContact O-OG 3.08Å; V5-L16 HydrophobicContact CG2-CD1 4Å; V5-P37 HydrophobicContact CG2-CB 4.33Å; V5-E40 HydrophobicContact CG1-CB 4.34Å; V5-E40 HydrophobicContact CG1-CG 4.04Å; V5-R44 PolarHBondContact O-NH1 3.5Å; V5-V49 HydrophobicContact CG1-CG1 4.33Å
6K51.8Low49.6Very low114 Ų11476.4 Ų76.450%0.49639%0.393SS..THydrogen-bonded Turntrans-60.3-28.8176.4-85.2-177.2178.7-172.40114.4L2 T3 L4 R44L2-K6 WeakPolarHBondContact O-CB 3.35Å; L2-K6 VanDerWaalsContact O-CG 3.27Å; L2-K6 WeakPolarHBondContact O-CG 3.47Å; L2-K6 PolarHBondContact O-N 3.22Å; T3-K6 WeakPolarHBondContact O-CB 3.33Å; L4-K6 PolarHBondContact O-N 2.7Å; K6-R44 VanDerWaalsContact CA-CZ 3.48Å; K6-R44 VanDerWaalsContact CA-NH2 3.25Å; K6-R44 PolarHBondContact O-NH1 3.17Å; K6-R44 PolarHBondContact O-NH2 3.22Å
7R47.1Very low49.9Very low213 Ų21377 Ų7780%0.80439%0.389SS*.THydrogen-bonded Turntrans-106.90.2-173.7-74.5-177.5170.6170.3-2.2114.1L4 V5 S9L4-R7 PolarHBondContact O-N 3.14Å; V5-R7 PolarHBondContact O-N 2.85Å; R7-S9 PolarHBondContact O-N 2.96Å
8S47.9Very low49.9Very low11 Ų1181.8 Ų81.88%0.07740%0.402CS..  trans-84.7106.2-169.657.10000113.4L4 V5 S12L4-S8 PolarHBondContact O-N 2.78Å; V5-S8 PolarHBondContact O-N 3.11Å; V5-S8 PolarHBondContact O-OG 3.3Å; V5-S8 VanDerWaalsContact O-OG 3.08Å; S8-S12 VanDerWaalsContact CA-CB 3.43Å; S8-S12 WeakPolarHBondContact CA-OG 3.32Å; S8-S12 WeakPolarHBondContact CB-OG 3.36Å
9S43.1Very low49.9Very low96 Ų9682.2 Ų82.267%0.67140%0.401SS*.  trans-107.6139.9158.757.10000109.9R7 E11 S12R7-S9 PolarHBondContact O-N 2.96Å; S9-E11 PolarHBondContact O-N 3.3Å; S9-S12 WeakPolarHBondContact O-CB 3.18Å; S9-S12 PolarHBondContact O-N 3.31Å
10G45.3Very low50Low60 Ų6079.1 Ų79.162%0.61939%0.386SS*.THydrogen-bonded Turntrans35.8-85.116700000117.6S12 L13G10-S12 PolarHBondContact O-N 3.15Å; G10-S12 VanDerWaalsContact O-N 3.15Å; G10-L13 WeakPolarHBondContact O-CB 3.46Å; G10-L13 PolarHBondContact O-N 3.43Å; G10-L13 VanDerWaalsContact O-N 3.1Å
11E44.6Very low50Low182 Ų18279.3 Ų79.385%0.8540%0.395SS*.THydrogen-bonded Turntrans-59.6-22.4178.2-71-171152.700114.3S9 L13S9-E11 PolarHBondContact O-N 3.3Å; E11-L13 VanDerWaalsContact C-N 3.26Å; E11-L13 PolarHBondContact O-N 3.32Å
12S53.3Low49.9Very low20 Ų2083.2 Ų83.214%0.1441%0.413CS..Hα-helixtrans-73-12.5176.5-176.30000113.8S8 S9 G10 K15 L16S8-S12 VanDerWaalsContact CA-CB 3.43Å; S8-S12 WeakPolarHBondContact CA-OG 3.32Å; S8-S12 WeakPolarHBondContact CB-OG 3.36Å; S9-S12 WeakPolarHBondContact O-CB 3.18Å; S9-S12 PolarHBondContact O-N 3.31Å; G10-S12 PolarHBondContact O-N 3.15Å; G10-S12 VanDerWaalsContact O-N 3.15Å; S12-K15 WeakPolarHBondContact O-CB 3.25Å; S12-K15 PolarHBondContact O-N 3.39Å; S12-L16 WeakPolarHBondContact O-CB 3.47Å; S12-L16 PolarHBondContact O-N 3.41Å
13L47.9Very low49.7Very low29 Ų2983 Ų8315%0.15242%0.415CS..Hα-helixtrans-70-39.6-177.4-168.775.5000111.9G10 E11 K15 L16 R17 E48 V49 A52G10-L13 WeakPolarHBondContact O-CB 3.46Å; G10-L13 PolarHBondContact O-N 3.43Å; G10-L13 VanDerWaalsContact O-N 3.1Å; E11-L13 VanDerWaalsContact C-N 3.26Å; E11-L13 PolarHBondContact O-N 3.32Å; L13-K15 VanDerWaalsContact C-N 3.3Å; L13-K15 PolarHBondContact O-N 2.69Å; L13-L16 HydrophobicContact CD1-CD2 4.5Å; L13-L16 PolarHBondContact O-N 2.71Å; L13-R17 WeakPolarHBondContact O-CG 3.42Å; L13-R17 PolarHBondContact O-N 3.04Å; L13-E48 HydrophobicContact CD1-CB 4.19Å; L13-E48 HydrophobicContact CD2-CB 4.01Å; L13-V49 HydrophobicContact CD1-CG2 3.93Å; L13-A52 HydrophobicContact CD1-CB 4.49Å
14H54.3Low49.4Very low143 Ų14382.1 Ų82.166%0.66243%0.425SS*.Hα-helixtrans-63.1-39172.6-73.1-63000111.6R18H14-R18 WeakPolarHBondContact O-CB 3.48Å; H14-R18 PolarHBondContact O-N 2.98Å
15K55.7Low49.6Very low135 Ų13584.2 Ų84.259%0.58743%0.432SS*.Hα-helixtrans-63.8-45.1172.4-71.9-179.8-179.6173.90110.7S12 L13 R18 F19S12-K15 WeakPolarHBondContact O-CB 3.25Å; S12-K15 PolarHBondContact O-N 3.39Å; L13-K15 VanDerWaalsContact C-N 3.3Å; L13-K15 PolarHBondContact O-N 2.69Å; K15-R18 PolarHBondContact O-N 2.99Å; K15-F19 HydrophobicContact CB-CD2 4.31Å; K15-F19 WeakPolarHBondContact O-CB 3.1Å; K15-F19 WeakPolarHBondContact O-CD2 3.44Å; K15-F19 PolarHBondContact O-N 3.49Å
16L56.9Low50.2Low4 Ų486 Ų862%0.02145%0.451CS..Hα-helixtrans-62-48.3178.9-172.976.2000111.8V5 S12 L13 R18 F19 L20 V49V5-L16 HydrophobicContact CG2-CD1 4Å; S12-L16 WeakPolarHBondContact O-CB 3.47Å; S12-L16 PolarHBondContact O-N 3.41Å; L13-L16 HydrophobicContact CD1-CD2 4.5Å; L13-L16 PolarHBondContact O-N 2.71Å; L16-R18 VanDerWaalsContact C-N 3.35Å; L16-R18 PolarHBondContact O-N 3.07Å; L16-F19 PolarHBondContact O-N 3.02Å; L16-L20 HydrophobicContact CD2-CD1 4.37Å; L16-L20 HydrophobicContact CG-CD1 3.91Å; L16-L20 VanDerWaalsContact O-CB 3.3Å; L16-L20 WeakPolarHBondContact O-CB 3.36Å; L16-L20 WeakPolarHBondContact O-CD1 3.4Å; L16-L20 WeakPolarHBondContact O-CG 3.49Å; L16-L20 PolarHBondContact O-N 3.26Å; L16-V49 HydrophobicContact CD2-CB 4.48Å; L16-V49 HydrophobicContact CD2-CG1 3.77Å; L16-V49 HydrophobicContact CD2-CG2 4.19Å
17R54.3Low51.2Low86 Ų8681.5 Ų81.533%0.32543%0.432SS..Hα-helixtrans-61.1-40.9176.1-73.4-176.7176.3-119.1-0.3111.7L13 C21 A52 E55 F56L13-R17 WeakPolarHBondContact O-CG 3.42Å; L13-R17 PolarHBondContact O-N 3.04Å; R17-C21 WeakPolarHBondContact O-CB 3.43Å; R17-C21 PolarHBondContact O-N 2.91Å; R17-C21 VanDerWaalsContact O-N 3.11Å; R17-C21 PolarHBondContact O-SG 3.39Å; R17-C21 VanDerWaalsContact O-SG 3.4Å; R17-A52 HydrophobicContact CG-CB 4.36Å; R17-E55 IonicContact CZ-OE1 3.66Å; R17-E55 IonicContact CZ-OE2 2.73Å; R17-E55 VanDerWaalsContact CZ-OE2 3.22Å; R17-E55 IonicContact NH1-OE1 3.85Å; R17-E55 IonicContact NH1-OE2 2.96Å; R17-E55 PolarHBondContact NH1-OE2 3.18Å; R17-E55 IonicContact NH2-OE1 2.71Å; R17-E55 PolarHBondContact NH2-OE1 3.09Å; R17-E55 IonicContact NH2-OE2 3.77Å; R17-E55 PolarHBondContact NH2-OE2 3.13Å; R17-F56 HydrophobicContact CG-CE2 4.45Å
18R49Very low52.7Low164 Ų16474 Ų7462%0.61941%0.408SS*.Hα-helixtrans-63.1-51.6172.1-86.6-172.2178.4138.2-0.6111.9H14 K15 L16 L20 C21 E22H14-R18 WeakPolarHBondContact O-CB 3.48Å; H14-R18 PolarHBondContact O-N 2.98Å; K15-R18 PolarHBondContact O-N 2.99Å; L16-R18 VanDerWaalsContact C-N 3.35Å; L16-R18 PolarHBondContact O-N 3.07Å; R18-L20 VanDerWaalsContact C-N 3.28Å; R18-L20 PolarHBondContact O-N 3.39Å; R18-C21 CarbonylContact O-C 3.58Å; R18-C21 WeakPolarHBondContact O-CA 3.2Å; R18-C21 WeakPolarHBondContact O-CB 3.21Å; R18-C21 PolarHBondContact O-N 3.04Å; R18-E22 WeakPolarHBondContact O-CB 3Å; R18-E22 VanDerWaalsContact O-CG 3.24Å; R18-E22 WeakPolarHBondContact O-CG 3.41Å; R18-E22 PolarHBondContact O-N 2.87Å
19F50.4Low54.3Low88 Ų8876.6 Ų76.639%0.38642%0.424SS..Hα-helixtrans-60-36.2179.5-89-68.2000113L4 K15 L16 A23L4-F19 HydrophobicContact CD1-CG 4.48Å; L4-F19 HydrophobicContact CD2-CD2 4.34Å; L4-F19 HydrophobicContact CD2-CE2 4.48Å; K15-F19 HydrophobicContact CB-CD2 4.31Å; K15-F19 WeakPolarHBondContact O-CB 3.1Å; K15-F19 WeakPolarHBondContact O-CD2 3.44Å; K15-F19 PolarHBondContact O-N 3.49Å; L16-F19 PolarHBondContact O-N 3.02Å; F19-A23 PolarHBondContact O-N 3.46Å
20L52.7Low56.1Low20 Ų2076.8 Ų76.811%0.10541%0.414CS..Hα-helixtrans-65-40.8172.9-86.4159.9000112.5M1 L16 R18 V27 L53 F56M1-L20 HydrophobicContact CE-CD2 3.04Å; M1-L20 HydrophobicContact CE-CG 3.9Å; L16-L20 HydrophobicContact CD2-CD1 4.37Å; L16-L20 HydrophobicContact CG-CD1 3.91Å; L16-L20 VanDerWaalsContact O-CB 3.3Å; L16-L20 WeakPolarHBondContact O-CB 3.36Å; L16-L20 WeakPolarHBondContact O-CD1 3.4Å; L16-L20 WeakPolarHBondContact O-CG 3.49Å; L16-L20 PolarHBondContact O-N 3.26Å; R18-L20 VanDerWaalsContact C-N 3.28Å; R18-L20 PolarHBondContact O-N 3.39Å; L20-V27 HydrophobicContact CD2-CG1 3.64Å; L20-L53 HydrophobicContact CD1-CD2 4.31Å; L20-F56 HydrophobicContact CB-CD1 4.29Å; L20-F56 HydrophobicContact CB-CD2 3.98Å; L20-F56 HydrophobicContact CB-CE1 4Å; L20-F56 HydrophobicContact CB-CE2 3.7Å; L20-F56 HydrophobicContact CB-CG 4.29Å; L20-F56 HydrophobicContact CB-CZ 3.71Å; L20-F56 HydrophobicContact CD1-CD2 3.56Å; L20-F56 HydrophobicContact CD1-CE2 3.71Å; L20-F56 HydrophobicContact CD1-CG 4.35Å; L20-F56 HydrophobicContact CD2-CB 4.39Å; L20-F56 HydrophobicContact CD2-CD2 4.2Å; L20-F56 HydrophobicContact CD2-CG 4.2Å; L20-F56 HydrophobicContact CG-CD2 4.13Å; L20-F56 HydrophobicContact CG-CE2 4.23Å
21C49.9Very low57.6Low85 Ų8575.9 Ų75.957%0.57440%0.395SS*.Hα-helixtrans-74.8-34.3175.8-77.30000113.5R17 R18 F56R17-C21 WeakPolarHBondContact O-CB 3.43Å; R17-C21 PolarHBondContact O-N 2.91Å; R17-C21 VanDerWaalsContact O-N 3.11Å; R17-C21 PolarHBondContact O-SG 3.39Å; R17-C21 VanDerWaalsContact O-SG 3.4Å; R18-C21 CarbonylContact O-C 3.58Å; R18-C21 WeakPolarHBondContact O-CA 3.2Å; R18-C21 WeakPolarHBondContact O-CB 3.21Å; R18-C21 PolarHBondContact O-N 3.04Å; C21-F56 VanDerWaalsContact SG-CE1 3.59Å; C21-F56 VanDerWaalsContact SG-CZ 3.52Å
22E45Very low59.3Low114 Ų11474.1 Ų74.153%0.53340%0.397SS..Hα-helixtrans-91.7-35.3-168.1-74168-175.400112.8R18R18-E22 WeakPolarHBondContact O-CB 3Å; R18-E22 VanDerWaalsContact O-CG 3.24Å; R18-E22 WeakPolarHBondContact O-CG 3.41Å; R18-E22 PolarHBondContact O-N 2.87Å
23A43.4Very low60.5Low20 Ų2075.1 Ų75.117%0.16541%0.407CS..SBendtrans-117.4121.6179.100000108.7F19 F25F19-A23 PolarHBondContact O-N 3.46Å; A23-F25 HydrophobicContact CB-CD2 3.35Å; A23-F25 HydrophobicContact CB-CE2 3.15Å; A23-F25 HydrophobicContact CB-CG 4.43Å; A23-F25 HydrophobicContact CB-CZ 4.1Å; A23-F25 WeakPolarHBondContact O-CD2 3.4Å; A23-F25 PolarHBondContact O-N 3.07Å
24G44.4Very low62.2Low81 Ų8173.9 Ų73.984%0.83540%0.401SS*.  trans-66.145.9-178.600000115
25F54.6Low63.7Low104 Ų10467.4 Ų67.446%0.45637%0.371SS..  trans-64.4135.4173.7-70.2-70000110.2M1 A23 V27M1-F25 HydrophobicContact SD-CB 4.4Å; A23-F25 HydrophobicContact CB-CD2 3.35Å; A23-F25 HydrophobicContact CB-CE2 3.15Å; A23-F25 HydrophobicContact CB-CG 4.43Å; A23-F25 HydrophobicContact CB-CZ 4.1Å; A23-F25 WeakPolarHBondContact O-CD2 3.4Å; A23-F25 PolarHBondContact O-N 3.07Å; F25-V27 PolarHBondContact O-N 3.45Å; F25-V27 VanDerWaalsContact O-N 3.13Å
26G62.1Low65.2Low38 Ų3861 Ų6139%0.39234%0.343SS..  trans-66.7111.5172.600000110.6N28 T29G26-N28 PolarHBondContact O-N 3.07Å; G26-T29 WeakPolarHBondContact O-CB 3.37Å; G26-T29 WeakPolarHBondContact O-CG2 3.48Å; G26-T29 PolarHBondContact O-N 3.03Å; G26-T29 VanDerWaalsContact O-N 3.1Å; G26-T29 PolarHBondContact O-OG1 2.9Å
27V74.5Confident66.4Low18 Ų1860.8 Ų60.811%0.10934%0.342CS..THydrogen-bonded Turntrans-52.5-20.4173.2-100.90000113.7M1 L20 F25 P37 L53 F56M1-V27 HydrophobicContact CE-CG1 3.89Å; L20-V27 HydrophobicContact CD2-CG1 3.64Å; F25-V27 PolarHBondContact O-N 3.45Å; F25-V27 VanDerWaalsContact O-N 3.13Å; V27-P37 VanDerWaalsContact O-CD 3.3Å; V27-P37 WeakPolarHBondContact O-CD 3.32Å; V27-P37 WeakPolarHBondContact O-CG 3.3Å; V27-L53 HydrophobicContact CG1-CD2 4.2Å; V27-F56 HydrophobicContact CG1-CB 3.9Å
28N78.2Confident67.8Low56 Ų5656.7 Ų56.730%0.29933%0.326SS..THydrogen-bonded Turntrans-108.417.9-176.4-68-22.2000113.9G26 Q30 A58 D59 I62G26-N28 PolarHBondContact O-N 3.07Å; N28-Q30 PolarHBondContact O-N 3.21Å; N28-A58 WeakPolarHBondContact OD1-CA 3.34Å; N28-D59 WeakPolarHBondContact ND2-CB 3.37Å; N28-D59 PolarHBondContact OD1-N 3.16Å; N28-I62 HydrophobicContact CB-CD1 3.51Å
29T80.1Confident69.4Low66 Ų6648.9 Ų48.941%0.40530%0.297SS..  trans-70.3122.8-179.443.30000112.1L2 G26 P37L2-T29 WeakPolarHBondContact CD1-O 3.41Å; G26-T29 WeakPolarHBondContact O-CB 3.37Å; G26-T29 WeakPolarHBondContact O-CG2 3.48Å; G26-T29 PolarHBondContact O-N 3.03Å; G26-T29 VanDerWaalsContact O-N 3.1Å; G26-T29 PolarHBondContact O-OG1 2.9Å; T29-P37 VanDerWaalsContact O-CD 3.31Å; T29-P37 WeakPolarHBondContact O-CD 3.4Å
30Q82.2Confident70.9Confident100 Ų10045.8 Ų45.847%0.46728%0.284SS..  trans-84.4142.5-179.7-66.5-179.3-59.300112.2N28 G34 D35 T36 I62 Q63N28-Q30 PolarHBondContact O-N 3.21Å; Q30-G34 WeakPolarHBondContact CG-O 3.48Å; Q30-G34 PolarHBondContact NE2-O 3.09Å; Q30-D35 CarbonylContact C-O 3.53Å; Q30-D35 WeakPolarHBondContact CA-O 3.34Å; Q30-T36 HydrophobicContact CG-CG2 3.91Å; Q30-I62 HydrophobicContact CG-CG2 4.17Å; Q30-Q63 PolarHBondContact NE2-O 3.02Å
31N77.2Confident72.3Confident40 Ų4044.9 Ų44.921%0.21428%0.279CS..  trans-81.2-174.8169.971.59.2000111.9L2 A33 G34 D35L2-N31 HydrophobicContact CD1-CB 3.72Å; L2-N31 HydrophobicContact CD2-CB 3.98Å; L2-N31 HydrophobicContact CG-CB 4.34Å; N31-A33 PolarHBondContact O-N 3.1Å; N31-A33 VanDerWaalsContact O-N 3.15Å; N31-A33 VanDerWaalsContact OD1-CA 3.28Å; N31-A33 WeakPolarHBondContact OD1-CA 3.35Å; N31-A33 WeakPolarHBondContact OD1-CB 3.48Å; N31-A33 PolarHBondContact OD1-N 3.16Å; N31-G34 PolarHBondContact O-N 3.18Å; N31-G34 PolarHBondContact OD1-N 3.23Å; N31-G34 VanDerWaalsContact OD1-N 3.13Å; N31-D35 PolarHBondContact N-O 2.78Å; N31-D35 WeakPolarHBondContact OD1-CB 3.28Å; N31-D35 PolarHBondContact OD1-N 3.08Å
32T79.8Confident73.9Confident145 Ų14540.9 Ų40.989%0.8925%0.252SS*.THydrogen-bonded Turntrans-62.3-17.6176.852.10000114.5N65T32-N65 PolarHBondContact O-ND2 3.45Å
33A78.4Confident75.5Confident42 Ų4238.8 Ų38.835%0.34724%0.241SC..THydrogen-bonded Turntrans-94.63.7173.300000113N31 D35 N65N31-A33 PolarHBondContact O-N 3.1Å; N31-A33 VanDerWaalsContact O-N 3.15Å; N31-A33 VanDerWaalsContact OD1-CA 3.28Å; N31-A33 WeakPolarHBondContact OD1-CA 3.35Å; N31-A33 WeakPolarHBondContact OD1-CB 3.48Å; N31-A33 PolarHBondContact OD1-N 3.16Å; A33-D35 PolarHBondContact O-N 3.02Å; A33-N65 VanDerWaalsContact C-CG 3.43Å; A33-N65 VanDerWaalsContact C-ND2 3.28Å; A33-N65 VanDerWaalsContact O-CB 3.27Å; A33-N65 WeakPolarHBondContact O-CB 3.44Å; A33-N65 VanDerWaalsContact O-CG 3.3Å; A33-N65 PolarHBondContact O-N 3.35Å
34G83.4Confident77Confident2 Ų242.1 Ų42.12%0.02125%0.249CC..SBendtrans78.72.6-174.700000113.9Q30 N31 N64 N65Q30-G34 WeakPolarHBondContact CG-O 3.48Å; Q30-G34 PolarHBondContact NE2-O 3.09Å; N31-G34 PolarHBondContact O-N 3.18Å; N31-G34 PolarHBondContact OD1-N 3.23Å; N31-G34 VanDerWaalsContact OD1-N 3.13Å; G34-N64 WeakPolarHBondContact O-CA 3.37Å; G34-N64 WeakPolarHBondContact O-CB 3.47Å; G34-N65 WeakPolarHBondContact CA-OD1 3.32Å; G34-N65 PolarHBondContact N-ND2 3.02Å
35D86.1Confident78.6Confident7 Ų739.8 Ų39.84%0.03723%0.225CC..  trans-78.6130.3-177.5-62.9-46.4000111Q30 N31 A33 H39 K43 N64Q30-D35 CarbonylContact C-O 3.53Å; Q30-D35 WeakPolarHBondContact CA-O 3.34Å; N31-D35 PolarHBondContact N-O 2.78Å; N31-D35 WeakPolarHBondContact OD1-CB 3.28Å; N31-D35 PolarHBondContact OD1-N 3.08Å; A33-D35 PolarHBondContact O-N 3.02Å; D35-H39 HydrophobicContact CB-CB 3.75Å; D35-H39 IonicContact OD1-CD2 3.22Å; D35-K43 WeakPolarHBondContact OD1-CE 3.46Å; D35-K43 IonicContact OD1-NZ 3.83Å; D35-K43 PolarHBondContact OD1-NZ 3.22Å; D35-K43 IonicContact OD2-NZ 3.82Å; D35-K43 PolarHBondContact OD2-NZ 3.47Å; D35-N64 WeakPolarHBondContact OD1-CB 3.48Å; D35-N64 PolarHBondContact OD1-ND2 2.91Å
36T86.1Confident79.6Confident0 Ų037.7 Ų37.70%022%0.219CC..  trans-77165.3166.671.90000110.6Q30 L38 H39 E40 I62Q30-T36 HydrophobicContact CG-CG2 3.91Å; T36-L38 PolarHBondContact O-N 3.39Å; T36-L38 VanDerWaalsContact O-N 3.11Å; T36-L38 PolarHBondContact OG1-N 2.83Å; T36-H39 PolarHBondContact N-ND1 3.26Å; T36-H39 VanDerWaalsContact N-ND1 3.11Å; T36-H39 WeakPolarHBondContact O-CB 3.4Å; T36-H39 PolarHBondContact O-N 2.95Å; T36-H39 PolarHBondContact OG1-N 3.13Å; T36-H39 PolarHBondContact OG1-ND1 3.08Å; T36-E40 PolarHBondContact O-N 3.32Å; T36-E40 VanDerWaalsContact O-N 3.17Å; T36-I62 HydrophobicContact CG2-CB 3.96Å; T36-I62 HydrophobicContact CG2-CD1 3.99Å; T36-I62 HydrophobicContact CG2-CG2 3.58Å
37P82.3Confident80.3Confident0 Ų038.7 Ų38.70%022%0.215CC..Hα-helixtrans-51.2-32.9170.7-26.834.1000113.1M1 L2 V5 V27 T29 E40 A41 L53M1-P37 HydrophobicContact CG-CB 4.47Å; M1-P37 HydrophobicContact CG-CG 4.02Å; M1-P37 HydrophobicContact SD-CB 4.16Å; M1-P37 HydrophobicContact SD-CG 3.42Å; M1-P37 WeakPolarHBondContact SD-CG 3.24Å; L2-P37 HydrophobicContact CG-CG 4.46Å; V5-P37 HydrophobicContact CG2-CB 4.33Å; V27-P37 VanDerWaalsContact O-CD 3.3Å; V27-P37 WeakPolarHBondContact O-CD 3.32Å; V27-P37 WeakPolarHBondContact O-CG 3.3Å; T29-P37 VanDerWaalsContact O-CD 3.31Å; T29-P37 WeakPolarHBondContact O-CD 3.4Å; P37-E40 PolarHBondContact O-N 2.93Å; P37-A41 WeakPolarHBondContact O-CB 3.46Å; P37-A41 PolarHBondContact O-N 2.95Å; P37-L53 HydrophobicContact CB-CD1 3.88Å; P37-L53 HydrophobicContact CB-CD2 4.03Å; P37-L53 WeakPolarHBondContact O-CD1 3.27Å
38L83.4Confident80.2Confident0 Ų043.5 Ų43.50%024%0.236CC..Hα-helixtrans-70.1-42.5177.4-173.465.6000111.9T36 E40 A41 I42 V50 L53 A58 W60 C70T36-L38 PolarHBondContact O-N 3.39Å; T36-L38 VanDerWaalsContact O-N 3.11Å; T36-L38 PolarHBondContact OG1-N 2.83Å; L38-E40 VanDerWaalsContact C-N 3.29Å; L38-E40 PolarHBondContact O-N 3.26Å; L38-A41 PolarHBondContact O-N 3.15Å; L38-I42 HydrophobicContact CD1-CD1 4.35Å; L38-I42 HydrophobicContact CG-CD1 3.99Å; L38-I42 VanDerWaalsContact O-CG1 3.31Å; L38-I42 WeakPolarHBondContact O-CG1 3.46Å; L38-I42 PolarHBondContact O-N 3.47Å; L38-V50 HydrophobicContact CD1-CB 4.49Å; L38-V50 HydrophobicContact CD1-CG1 4.06Å; L38-V50 HydrophobicContact CD1-CG2 4.46Å; L38-L53 HydrophobicContact CB-CD1 4.43Å; L38-L53 HydrophobicContact CD1-CB 4.21Å; L38-L53 HydrophobicContact CD1-CD1 4.48Å; L38-A58 HydrophobicContact CB-CB 4.23Å; L38-A58 HydrophobicContact CD2-CB 4.09Å; L38-W60 HydrophobicContact CD1-CZ2 4.38Å; L38-W60 HydrophobicContact CD2-CB 4.46Å; L38-W60 HydrophobicContact CD2-CD2 3.84Å; L38-W60 HydrophobicContact CD2-CG 3.74Å; L38-W60 HydrophobicContact CD2-CZ2 4.43Å; L38-C70 HydrophobicContact CD2-CB 3.86Å; L38-C70 HydrophobicContact CG-CB 4.21Å
39H83.9Confident80Confident0 Ų041.1 Ų41.10%022%0.224CC..Hα-helixtrans-56.6-45.4172.9-70.682.2000111.1D35 T36 I42 K43 I62 F68 C70 L73D35-H39 HydrophobicContact CB-CB 3.75Å; D35-H39 IonicContact OD1-CD2 3.22Å; T36-H39 PolarHBondContact N-ND1 3.26Å; T36-H39 VanDerWaalsContact N-ND1 3.11Å; T36-H39 WeakPolarHBondContact O-CB 3.4Å; T36-H39 PolarHBondContact O-N 2.95Å; T36-H39 PolarHBondContact OG1-N 3.13Å; T36-H39 PolarHBondContact OG1-ND1 3.08Å; H39-I42 PolarHBondContact O-N 3.5Å; H39-K43 WeakPolarHBondContact O-CB 3.25Å; H39-K43 VanDerWaalsContact O-CG 3.27Å; H39-K43 WeakPolarHBondContact O-CG 3.37Å; H39-K43 PolarHBondContact O-N 3.36Å; H39-I62 PolarHBondContact CE1-O 2.95Å; H39-I62 PolarHBondContact NE2-O 2.93Å; H39-F68 PolarHBondContact NE2-O 3.46Å; H39-C70 PolarHBondContact CE1-SG 3.01Å; H39-C70 VanDerWaalsContact CG-SG 3.54Å; H39-C70 PolarHBondContact ND1-SG 3.02Å; H39-L73 WeakPolarHBondContact CD2-CD1 3.38Å
40E81.5Confident80Confident24 Ų2438 Ų3811%0.11221%0.205CC..Hα-helixtrans-64.9-41.1179.7-174.168.1-157.700111.5L2 V5 T36 P37 L38 K43 R44L2-E40 HydrophobicContact CD2-CB 4.13Å; V5-E40 HydrophobicContact CG1-CB 4.34Å; V5-E40 HydrophobicContact CG1-CG 4.04Å; T36-E40 PolarHBondContact O-N 3.32Å; T36-E40 VanDerWaalsContact O-N 3.17Å; P37-E40 PolarHBondContact O-N 2.93Å; L38-E40 VanDerWaalsContact C-N 3.29Å; L38-E40 PolarHBondContact O-N 3.26Å; E40-K43 PolarHBondContact O-N 3.32Å; E40-R44 WeakPolarHBondContact O-CD 3.48Å; E40-R44 VanDerWaalsContact O-CG 3.3Å; E40-R44 WeakPolarHBondContact O-CG 3.35Å; E40-R44 PolarHBondContact O-N 2.9Å; E40-R44 VanDerWaalsContact O-N 3.12Å; E40-R44 IonicContact OE1-CZ 2.81Å; E40-R44 IonicContact OE1-NE 2.97Å; E40-R44 PolarHBondContact OE1-NE 3.2Å; E40-R44 IonicContact OE1-NH2 3.64Å; E40-R44 PolarHBondContact OE1-NH2 3.07Å
41A81.6Confident79.8Confident0 Ų034.8 Ų34.80%019%0.19CC..Hα-helixtrans-63.6-41.5175.900000112.2P37 L38 R44 G45 D46 V49 V50 L53P37-A41 WeakPolarHBondContact O-CB 3.46Å; P37-A41 PolarHBondContact O-N 2.95Å; L38-A41 PolarHBondContact O-N 3.15Å; A41-R44 PolarHBondContact O-N 2.97Å; A41-G45 PolarHBondContact O-N 3.39Å; A41-D46 PolarHBondContact O-N 2.99Å; A41-D46 VanDerWaalsContact O-N 3.16Å; A41-V49 HydrophobicContact CB-CB 4.16Å; A41-V49 HydrophobicContact CB-CG1 3.75Å; A41-V50 HydrophobicContact CB-CG2 3.69Å; A41-L53 HydrophobicContact CB-CD1 4Å
42I83Confident79.6Confident1 Ų132.9 Ų32.91%0.00518%0.18CC..Hα-helixtrans-68-42.3176.3-66169.5000111.2L38 H39 R44 G45 V50 W60 C70 L73 I79L38-I42 HydrophobicContact CD1-CD1 4.35Å; L38-I42 HydrophobicContact CG-CD1 3.99Å; L38-I42 VanDerWaalsContact O-CG1 3.31Å; L38-I42 WeakPolarHBondContact O-CG1 3.46Å; L38-I42 PolarHBondContact O-N 3.47Å; H39-I42 PolarHBondContact O-N 3.5Å; I42-R44 PolarHBondContact O-N 3.1Å; I42-G45 PolarHBondContact O-N 3.28Å; I42-V50 HydrophobicContact CG1-CG2 3.87Å; I42-W60 HydrophobicContact CD1-CE3 4.49Å; I42-W60 HydrophobicContact CD1-CH2 4.25Å; I42-W60 HydrophobicContact CD1-CZ3 4.02Å; I42-C70 HydrophobicContact CD1-CB 3.57Å; I42-L73 HydrophobicContact CG2-CB 3.93Å; I42-I79 HydrophobicContact CG2-CD1 4.18Å
43K78.5Confident79.6Confident71 Ų7126 Ų2631%0.30914%0.138SC..Hα-helixtrans-59-29.5174.6-76.9178.4-171.5-176.40112.7D35 H39 E40 L73 R77D35-K43 WeakPolarHBondContact OD1-CE 3.46Å; D35-K43 IonicContact OD1-NZ 3.83Å; D35-K43 PolarHBondContact OD1-NZ 3.22Å; D35-K43 IonicContact OD2-NZ 3.82Å; D35-K43 PolarHBondContact OD2-NZ 3.47Å; H39-K43 WeakPolarHBondContact O-CB 3.25Å; H39-K43 VanDerWaalsContact O-CG 3.27Å; H39-K43 WeakPolarHBondContact O-CG 3.37Å; H39-K43 PolarHBondContact O-N 3.36Å; E40-K43 PolarHBondContact O-N 3.32Å; K43-L73 HydrophobicContact CG-CD2 4.44Å; K43-R77 PolarHBondContact O-NH1 3.15Å; K43-R77 PolarHBondContact O-NH2 2.97Å
44R76.7Confident79.5Confident89 Ų8926.3 Ų26.334%0.33614%0.136SC..Hα-helixtrans-82.9-26.2174.9-70.1163.2-177.3-111.6-21.8113.4V5 K6 E40 A41 I42 D46V5-R44 PolarHBondContact O-NH1 3.5Å; K6-R44 VanDerWaalsContact CA-CZ 3.48Å; K6-R44 VanDerWaalsContact CA-NH2 3.25Å; K6-R44 PolarHBondContact O-NH1 3.17Å; K6-R44 PolarHBondContact O-NH2 3.22Å; E40-R44 WeakPolarHBondContact O-CD 3.48Å; E40-R44 VanDerWaalsContact O-CG 3.3Å; E40-R44 WeakPolarHBondContact O-CG 3.35Å; E40-R44 PolarHBondContact O-N 2.9Å; E40-R44 VanDerWaalsContact O-N 3.12Å; E40-R44 IonicContact OE1-CZ 2.81Å; E40-R44 IonicContact OE1-NE 2.97Å; E40-R44 PolarHBondContact OE1-NE 3.2Å; E40-R44 IonicContact OE1-NH2 3.64Å; E40-R44 PolarHBondContact OE1-NH2 3.07Å; A41-R44 PolarHBondContact O-N 2.97Å; I42-R44 PolarHBondContact O-N 3.1Å; R44-D46 VanDerWaalsContact C-N 3.32Å; R44-D46 HydrophobicContact CB-CB 4.4Å
45G76Confident79Confident32 Ų3229.9 Ų29.933%0.3315%0.152SC..THydrogen-bonded Turntrans77.218.2-17000000113.2A41 I42 L47A41-G45 PolarHBondContact O-N 3.39Å; I42-G45 PolarHBondContact O-N 3.28Å; G45-L47 PolarHBondContact O-N 3Å
46D76.7Confident78.3Confident60 Ų6031.8 Ų31.832%0.32116%0.16SC..  trans-77.483.5179.6-82.3-36.9000110.7A41 R44 E48 V49 V50A41-D46 PolarHBondContact O-N 2.99Å; A41-D46 VanDerWaalsContact O-N 3.16Å; R44-D46 VanDerWaalsContact C-N 3.32Å; R44-D46 HydrophobicContact CB-CB 4.4Å; D46-E48 PolarHBondContact O-N 2.84Å; D46-E48 VanDerWaalsContact O-N 3.16Å; D46-V49 HydrophobicContact CB-CB 4.04Å; D46-V49 HydrophobicContact CB-CG2 4.06Å; D46-V49 PolarHBondContact O-N 2.89Å; D46-V49 VanDerWaalsContact O-N 3.1Å; D46-V50 WeakPolarHBondContact O-CG2 3.42Å; D46-V50 PolarHBondContact O-N 3.21Å
47L76Confident77.7Confident59 Ų5934 Ų3431%0.30918%0.183SC..Hα-helixtrans-52.7-36.4179.7-71.2169000112.9G45 V50 N51 I79 K82G45-L47 PolarHBondContact O-N 3Å; L47-V50 PolarHBondContact O-N 2.75Å; L47-N51 WeakPolarHBondContact O-CB 3.41Å; L47-N51 PolarHBondContact O-N 3.29Å; L47-N51 PolarHBondContact O-ND2 3.19Å; L47-I79 HydrophobicContact CD2-CB 4.42Å; L47-I79 HydrophobicContact CD2-CG1 4.36Å; L47-I79 HydrophobicContact CD2-CG2 3.68Å; L47-K82 HydrophobicContact CD1-CB 4.47Å
48E72.1Confident77.6Confident119 Ų11934.4 Ų34.456%0.55619%0.186SC*.Hα-helixtrans-68.1-38.8-179.8-64.6-177.3173.900112.9L13 D46 A52L13-E48 HydrophobicContact CD1-CB 4.19Å; L13-E48 HydrophobicContact CD2-CB 4.01Å; D46-E48 PolarHBondContact O-N 2.84Å; D46-E48 VanDerWaalsContact O-N 3.16Å; E48-A52 WeakPolarHBondContact O-CB 3.4Å; E48-A52 PolarHBondContact O-N 3.42Å
49V75.2Confident77.3Confident7 Ų737.5 Ų37.54%0.04220%0.203CC..Hα-helixtrans-74.5-38.3176.6178.30000110.3V5 L13 L16 A41 D46 A52 L53V5-V49 HydrophobicContact CG1-CG1 4.33Å; L13-V49 HydrophobicContact CD1-CG2 3.93Å; L16-V49 HydrophobicContact CD2-CB 4.48Å; L16-V49 HydrophobicContact CD2-CG1 3.77Å; L16-V49 HydrophobicContact CD2-CG2 4.19Å; A41-V49 HydrophobicContact CB-CB 4.16Å; A41-V49 HydrophobicContact CB-CG1 3.75Å; D46-V49 HydrophobicContact CB-CB 4.04Å; D46-V49 HydrophobicContact CB-CG2 4.06Å; D46-V49 PolarHBondContact O-N 2.89Å; D46-V49 VanDerWaalsContact O-N 3.1Å; V49-A52 PolarHBondContact O-N 3.13Å; V49-L53 HydrophobicContact CG1-CD1 3.83Å; V49-L53 HydrophobicContact CG1-CG 4.21Å; V49-L53 WeakPolarHBondContact O-CB 3.48Å; V49-L53 VanDerWaalsContact O-CG 3.3Å; V49-L53 WeakPolarHBondContact O-CG 3.48Å; V49-L53 PolarHBondContact O-N 3.06Å
50V79.6Confident77.4Confident0 Ų039.5 Ų39.50%021%0.21CC..Hα-helixtrans-59-47.7172.2172.50000110.3L38 A41 I42 D46 L47 L53 T54 W60 I83L38-V50 HydrophobicContact CD1-CB 4.49Å; L38-V50 HydrophobicContact CD1-CG1 4.06Å; L38-V50 HydrophobicContact CD1-CG2 4.46Å; A41-V50 HydrophobicContact CB-CG2 3.69Å; I42-V50 HydrophobicContact CG1-CG2 3.87Å; D46-V50 WeakPolarHBondContact O-CG2 3.42Å; D46-V50 PolarHBondContact O-N 3.21Å; L47-V50 PolarHBondContact O-N 2.75Å; V50-L53 PolarHBondContact O-N 3.49Å; V50-T54 VanDerWaalsContact O-CB 3.3Å; V50-T54 WeakPolarHBondContact O-CB 3.49Å; V50-T54 PolarHBondContact O-N 3.21Å; V50-T54 PolarHBondContact O-OG1 3.32Å; V50-W60 HydrophobicContact CG1-CH2 4.1Å; V50-W60 HydrophobicContact CG1-CZ2 3.95Å; V50-I83 HydrophobicContact CG1-CD1 4.4Å
51N77.3Confident77.3Confident32 Ų3241.8 Ų41.817%0.17123%0.229CC..Hα-helixtrans-61.8-45.6176.8-73.5-16.4000111.3L47 T54 E55L47-N51 WeakPolarHBondContact O-CB 3.41Å; L47-N51 PolarHBondContact O-N 3.29Å; L47-N51 PolarHBondContact O-ND2 3.19Å; N51-T54 PolarHBondContact O-N 3.04Å; N51-E55 WeakPolarHBondContact O-CB 3.26Å; N51-E55 VanDerWaalsContact O-CG 3.29Å; N51-E55 WeakPolarHBondContact O-CG 3.4Å; N51-E55 PolarHBondContact O-N 3.26Å
52A73.9Confident77.5Confident0 Ų043.5 Ų43.50%024%0.238CC..Hα-helixtrans-60.9-49.3176.500000111.8L13 R17 E48 V49 T54 E55 F56L13-A52 HydrophobicContact CD1-CB 4.49Å; R17-A52 HydrophobicContact CG-CB 4.36Å; E48-A52 WeakPolarHBondContact O-CB 3.4Å; E48-A52 PolarHBondContact O-N 3.42Å; V49-A52 PolarHBondContact O-N 3.13Å; A52-T54 VanDerWaalsContact C-N 3.28Å; A52-T54 PolarHBondContact O-N 3.01Å; A52-E55 WeakPolarHBondContact O-CB 3.42Å; A52-E55 PolarHBondContact O-N 3.48Å; A52-F56 WeakPolarHBondContact O-CD2 3.18Å; A52-F56 PolarHBondContact O-N 3.33Å
53L79.2Confident77.5Confident0 Ų049 Ų490%026%0.263CS..Hα-helixtrans-62.4-37178.9-72.1171.3000112.2M1 L20 V27 P37 L38 A41 V49 V50 F56 G57 A58M1-L53 HydrophobicContact CE-CD2 4.1Å; L20-L53 HydrophobicContact CD1-CD2 4.31Å; V27-L53 HydrophobicContact CG1-CD2 4.2Å; P37-L53 HydrophobicContact CB-CD1 3.88Å; P37-L53 HydrophobicContact CB-CD2 4.03Å; P37-L53 WeakPolarHBondContact O-CD1 3.27Å; L38-L53 HydrophobicContact CB-CD1 4.43Å; L38-L53 HydrophobicContact CD1-CB 4.21Å; L38-L53 HydrophobicContact CD1-CD1 4.48Å; A41-L53 HydrophobicContact CB-CD1 4Å; V49-L53 HydrophobicContact CG1-CD1 3.83Å; V49-L53 HydrophobicContact CG1-CG 4.21Å; V49-L53 WeakPolarHBondContact O-CB 3.48Å; V49-L53 VanDerWaalsContact O-CG 3.3Å; V49-L53 WeakPolarHBondContact O-CG 3.48Å; V49-L53 PolarHBondContact O-N 3.06Å; V50-L53 PolarHBondContact O-N 3.49Å; L53-F56 CarbonylContact O-C 3.59Å; L53-F56 PolarHBondContact O-N 3.27Å; L53-G57 PolarHBondContact O-N 3.25Å; L53-A58 HydrophobicContact CB-CB 3.98Å; L53-A58 WeakPolarHBondContact O-CB 3.32Å; L53-A58 PolarHBondContact O-N 3.01Å
54T77.9Confident77.8Confident49 Ų4946 Ų4630%0.30125%0.25SS..Hα-helixtrans-68.4-40.4175.2-510000111.3V50 N51 A52 F56 G57V50-T54 VanDerWaalsContact O-CB 3.3Å; V50-T54 WeakPolarHBondContact O-CB 3.49Å; V50-T54 PolarHBondContact O-N 3.21Å; V50-T54 PolarHBondContact O-OG1 3.32Å; N51-T54 PolarHBondContact O-N 3.04Å; A52-T54 VanDerWaalsContact C-N 3.28Å; A52-T54 PolarHBondContact O-N 3.01Å; T54-F56 PolarHBondContact O-N 3.45Å; T54-G57 PolarHBondContact O-N 2.82Å
55E71Confident78.2Confident77 Ų7747.3 Ų47.336%0.3626%0.264SS..Hα-helixtrans-56.9-35170.7-75.7169.7-15800111.6R17 N51 A52 G57R17-E55 IonicContact CZ-OE1 3.66Å; R17-E55 IonicContact CZ-OE2 2.73Å; R17-E55 VanDerWaalsContact CZ-OE2 3.22Å; R17-E55 IonicContact NH1-OE1 3.85Å; R17-E55 IonicContact NH1-OE2 2.96Å; R17-E55 PolarHBondContact NH1-OE2 3.18Å; R17-E55 IonicContact NH2-OE1 2.71Å; R17-E55 PolarHBondContact NH2-OE1 3.09Å; R17-E55 IonicContact NH2-OE2 3.77Å; R17-E55 PolarHBondContact NH2-OE2 3.13Å; N51-E55 WeakPolarHBondContact O-CB 3.26Å; N51-E55 VanDerWaalsContact O-CG 3.29Å; N51-E55 WeakPolarHBondContact O-CG 3.4Å; N51-E55 PolarHBondContact O-N 3.26Å; A52-E55 WeakPolarHBondContact O-CB 3.42Å; A52-E55 PolarHBondContact O-N 3.48Å; E55-G57 VanDerWaalsContact C-N 3.33Å
56F72.4Confident78.5Confident48 Ų4852 Ų5221%0.21128%0.281CS..THydrogen-bonded Turntrans-86.87.7176.8-74.4-75.1000114.5R17 L20 C21 V27 A52 L53 T54R17-F56 HydrophobicContact CG-CE2 4.45Å; L20-F56 HydrophobicContact CB-CD1 4.29Å; L20-F56 HydrophobicContact CB-CD2 3.98Å; L20-F56 HydrophobicContact CB-CE1 4Å; L20-F56 HydrophobicContact CB-CE2 3.7Å; L20-F56 HydrophobicContact CB-CG 4.29Å; L20-F56 HydrophobicContact CB-CZ 3.71Å; L20-F56 HydrophobicContact CD1-CD2 3.56Å; L20-F56 HydrophobicContact CD1-CE2 3.71Å; L20-F56 HydrophobicContact CD1-CG 4.35Å; L20-F56 HydrophobicContact CD2-CB 4.39Å; L20-F56 HydrophobicContact CD2-CD2 4.2Å; L20-F56 HydrophobicContact CD2-CG 4.2Å; L20-F56 HydrophobicContact CG-CD2 4.13Å; L20-F56 HydrophobicContact CG-CE2 4.23Å; C21-F56 VanDerWaalsContact SG-CE1 3.59Å; C21-F56 VanDerWaalsContact SG-CZ 3.52Å; V27-F56 HydrophobicContact CG1-CB 3.9Å; A52-F56 WeakPolarHBondContact O-CD2 3.18Å; A52-F56 PolarHBondContact O-N 3.33Å; L53-F56 CarbonylContact O-C 3.59Å; L53-F56 PolarHBondContact O-N 3.27Å; T54-F56 PolarHBondContact O-N 3.45Å
57G73.1Confident78.7Confident47 Ų4750.7 Ų50.749%0.48528%0.282SS..THydrogen-bonded Turntrans78.931.817500000115L53 T54 E55 D59L53-G57 PolarHBondContact O-N 3.25Å; T54-G57 PolarHBondContact O-N 2.82Å; E55-G57 VanDerWaalsContact C-N 3.33Å; G57-D59 PolarHBondContact O-N 3.41Å
58A81.1Confident79Confident8 Ų851.8 Ų51.87%0.06629%0.285CS..  trans-59.8133.7169.900000111.2N28 L38 L53N28-A58 WeakPolarHBondContact OD1-CA 3.34Å; L38-A58 HydrophobicContact CB-CB 4.23Å; L38-A58 HydrophobicContact CD2-CB 4.09Å; L53-A58 HydrophobicContact CB-CB 3.98Å; L53-A58 WeakPolarHBondContact O-CB 3.32Å; L53-A58 PolarHBondContact O-N 3.01Å
59D77.2Confident79.5Confident65 Ų6547.3 Ų47.335%0.34826%0.264SS..  trans-86.6121.6-177.7-171.4-9.5000110.3N28 G57 S61 I62N28-D59 WeakPolarHBondContact ND2-CB 3.37Å; N28-D59 PolarHBondContact OD1-N 3.16Å; G57-D59 PolarHBondContact O-N 3.41Å; D59-S61 VanDerWaalsContact C-N 3.33Å; D59-S61 VanDerWaalsContact CG-OG 3.29Å; D59-S61 WeakPolarHBondContact OD1-CB 3.26Å; D59-S61 PolarHBondContact OD1-N 3.33Å; D59-S61 PolarHBondContact OD1-OG 2.91Å; D59-S61 PolarHBondContact OD2-OG 2.92Å; D59-I62 HydrophobicContact CB-CD1 3.85Å; D59-I62 HydrophobicContact CB-CG1 4.07Å
60W85.5Confident79.8Confident42 Ų4247 Ų4716%0.15926%0.262CS..THydrogen-bonded Turntrans-79.4-17.3-178.4-73.664.3000113.1L38 I42 V50 C70 N71 I83L38-W60 HydrophobicContact CD1-CZ2 4.38Å; L38-W60 HydrophobicContact CD2-CB 4.46Å; L38-W60 HydrophobicContact CD2-CD2 3.84Å; L38-W60 HydrophobicContact CD2-CG 3.74Å; L38-W60 HydrophobicContact CD2-CZ2 4.43Å; I42-W60 HydrophobicContact CD1-CE3 4.49Å; I42-W60 HydrophobicContact CD1-CH2 4.25Å; I42-W60 HydrophobicContact CD1-CZ3 4.02Å; V50-W60 HydrophobicContact CG1-CH2 4.1Å; V50-W60 HydrophobicContact CG1-CZ2 3.95Å; W60-C70 HydrophobicContact CB-CB 4.28Å; W60-C70 HydrophobicContact CD2-CB 4.28Å; W60-C70 HydrophobicContact CE3-CB 3.93Å; W60-C70 HydrophobicContact CG-CB 4.47Å; W60-C70 WeakPolarHBondContact O-CB 3.34Å; W60-C70 PolarHBondContact O-N 2.89Å; W60-C70 VanDerWaalsContact O-N 3.07Å; W60-N71 VanDerWaalsContact CE3-OD1 3.3Å; W60-I83 HydrophobicContact CH2-CD1 3.53Å; W60-I83 HydrophobicContact CZ2-CD1 4.1Å
61S80.1Confident79.7Confident71 Ų7150 Ų5050%0.49728%0.278SS..THydrogen-bonded Turntrans-86.6-7-173.869.40000114.6D59 Q63D59-S61 VanDerWaalsContact C-N 3.33Å; D59-S61 VanDerWaalsContact CG-OG 3.29Å; D59-S61 WeakPolarHBondContact OD1-CB 3.26Å; D59-S61 PolarHBondContact OD1-N 3.33Å; D59-S61 PolarHBondContact OD1-OG 2.91Å; D59-S61 PolarHBondContact OD2-OG 2.92Å; S61-Q63 PolarHBondContact O-N 2.99Å
62I84.2Confident79.7Confident36 Ų3652.7 Ų52.719%0.18529%0.29CS..  trans-70.7130.7179.3-63173.3000108.8N28 Q30 T36 H39 D59 D69N28-I62 HydrophobicContact CB-CD1 3.51Å; Q30-I62 HydrophobicContact CG-CG2 4.17Å; T36-I62 HydrophobicContact CG2-CB 3.96Å; T36-I62 HydrophobicContact CG2-CD1 3.99Å; T36-I62 HydrophobicContact CG2-CG2 3.58Å; H39-I62 PolarHBondContact CE1-O 2.95Å; H39-I62 PolarHBondContact NE2-O 2.93Å; D59-I62 HydrophobicContact CB-CD1 3.85Å; D59-I62 HydrophobicContact CB-CG1 4.07Å; I62-D69 WeakPolarHBondContact O-CA 3.31Å
63Q84.4Confident79.7Confident116 Ų11653.9 Ų53.954%0.54230%0.296SS..BIsolated β-bridgetrans-95.7140177.1-69.3178.8-18.700111.6Q30 S61 G67 F68 D69Q30-Q63 PolarHBondContact NE2-O 3.02Å; S61-Q63 PolarHBondContact O-N 2.99Å; Q63-G67 PolarHBondContact NE2-O 3.36Å; Q63-F68 WeakPolarHBondContact CA-O 3.48Å; Q63-D69 HydrophobicContact CG-CB 4.01Å
64N84.7Confident79.4Confident8 Ų854.3 Ų54.34%0.04330%0.299CS..  trans-79.9179.9169.871.18.8000112.5G34 D35 L66 G67 F68G34-N64 WeakPolarHBondContact O-CA 3.37Å; G34-N64 WeakPolarHBondContact O-CB 3.47Å; D35-N64 WeakPolarHBondContact OD1-CB 3.48Å; D35-N64 PolarHBondContact OD1-ND2 2.91Å; N64-L66 PolarHBondContact O-N 3.26Å; N64-L66 WeakPolarHBondContact OD1-CA 3.46Å; N64-L66 WeakPolarHBondContact OD1-CB 3.35Å; N64-L66 PolarHBondContact OD1-N 3.29Å; N64-G67 PolarHBondContact O-N 2.96Å; N64-G67 PolarHBondContact OD1-N 3.47Å; N64-F68 PolarHBondContact N-O 2.99Å; N64-F68 PolarHBondContact OD1-N 3.09Å; N64-F68 PolarHBondContact OD1-O 3.16Å
65N85.2Confident78.9Confident117 Ų11759.5 Ų59.563%0.62632%0.318SS*.THydrogen-bonded Turntrans-67.5-9.6-178.3-65.2-9000113.7T32 A33 G34T32-N65 PolarHBondContact O-ND2 3.45Å; A33-N65 VanDerWaalsContact C-CG 3.43Å; A33-N65 VanDerWaalsContact C-ND2 3.28Å; A33-N65 VanDerWaalsContact O-CB 3.27Å; A33-N65 WeakPolarHBondContact O-CB 3.44Å; A33-N65 VanDerWaalsContact O-CG 3.3Å; A33-N65 PolarHBondContact O-N 3.35Å; G34-N65 WeakPolarHBondContact CA-OD1 3.32Å; G34-N65 PolarHBondContact N-ND2 3.02Å
66L81.1Confident78.3Confident130 Ų13063 Ų6368%0.68133%0.334SS*.THydrogen-bonded Turntrans-91.5-3173.7-59.8173.6000112.1N64 F68N64-L66 PolarHBondContact O-N 3.26Å; N64-L66 WeakPolarHBondContact OD1-CA 3.46Å; N64-L66 WeakPolarHBondContact OD1-CB 3.35Å; N64-L66 PolarHBondContact OD1-N 3.29Å; L66-F68 HydrophobicContact CB-CD2 3.64Å; L66-F68 HydrophobicContact CB-CE2 3.92Å
67G81.5Confident77.3Confident34 Ų3466.8 Ų66.835%0.35135%0.347SS..SBendtrans86.51.4179.900000114.9Q63 N64Q63-G67 PolarHBondContact NE2-O 3.36Å; N64-G67 PolarHBondContact O-N 2.96Å; N64-G67 PolarHBondContact OD1-N 3.47Å
68F82.6Confident76.3Confident81 Ų8171.9 Ų71.936%0.35537%0.369SS..  trans-88.2133.8-179.8-61.9-68.9000110.9H39 Q63 N64 L66 L73H39-F68 PolarHBondContact NE2-O 3.46Å; Q63-F68 WeakPolarHBondContact CA-O 3.48Å; N64-F68 PolarHBondContact N-O 2.99Å; N64-F68 PolarHBondContact OD1-N 3.09Å; N64-F68 PolarHBondContact OD1-O 3.16Å; L66-F68 HydrophobicContact CB-CD2 3.64Å; L66-F68 HydrophobicContact CB-CE2 3.92Å; F68-L73 HydrophobicContact CB-CD1 4.02Å; F68-L73 HydrophobicContact CB-CG 4.15Å
69D83.3Confident74.8Confident25 Ų2572.1 Ų72.113%0.13437%0.369CS..BIsolated β-bridgetrans-89.917116679.9-2.9000111.2I62 Q63 N71 E72 L73I62-D69 WeakPolarHBondContact O-CA 3.31Å; Q63-D69 HydrophobicContact CG-CB 4.01Å; D69-N71 PolarHBondContact O-N 3.03Å; D69-N71 WeakPolarHBondContact OD1-CB 3.49Å; D69-N71 PolarHBondContact OD1-N 3.38Å; D69-N71 VanDerWaalsContact OD1-N 3.11Å; D69-N71 PolarHBondContact OD2-ND2 2.98Å; D69-E72 PolarHBondContact O-N 2.76Å; D69-E72 WeakPolarHBondContact OD1-CB 3.2Å; D69-E72 WeakPolarHBondContact OD1-CG 3.32Å; D69-E72 PolarHBondContact OD1-N 3.43Å; D69-L73 PolarHBondContact O-N 3.25Å; D69-L73 VanDerWaalsContact O-N 3.15Å
70C81.1Confident73.4Confident0 Ų075.6 Ų75.60%039%0.387CS..Hα-helixtrans-67.1-26.3-179.9-71.80000112.7L38 H39 I42 W60 S74L38-C70 HydrophobicContact CD2-CB 3.86Å; L38-C70 HydrophobicContact CG-CB 4.21Å; H39-C70 PolarHBondContact CE1-SG 3.01Å; H39-C70 VanDerWaalsContact CG-SG 3.54Å; H39-C70 PolarHBondContact ND1-SG 3.02Å; I42-C70 HydrophobicContact CD1-CB 3.57Å; W60-C70 HydrophobicContact CB-CB 4.28Å; W60-C70 HydrophobicContact CD2-CB 4.28Å; W60-C70 HydrophobicContact CE3-CB 3.93Å; W60-C70 HydrophobicContact CG-CB 4.47Å; W60-C70 WeakPolarHBondContact O-CB 3.34Å; W60-C70 PolarHBondContact O-N 2.89Å; W60-C70 VanDerWaalsContact O-N 3.07Å; C70-S74 WeakPolarHBondContact O-CB 3.13Å; C70-S74 PolarHBondContact O-N 3.02Å; C70-S74 PolarHBondContact O-OG 3.39Å
71N77.9Confident71.3Confident63 Ų6378.9 Ų78.934%0.33742%0.417SS..Hα-helixtrans-71.9-36.7178.2-60.8-57.4000112.3W60 D69 S74 K75W60-N71 VanDerWaalsContact CE3-OD1 3.3Å; D69-N71 PolarHBondContact O-N 3.03Å; D69-N71 WeakPolarHBondContact OD1-CB 3.49Å; D69-N71 PolarHBondContact OD1-N 3.38Å; D69-N71 VanDerWaalsContact OD1-N 3.11Å; D69-N71 PolarHBondContact OD2-ND2 2.98Å; N71-S74 PolarHBondContact O-OG 3.35Å; N71-K75 WeakPolarHBondContact O-CG 3.45Å; N71-K75 PolarHBondContact O-N 3.28Å
72E76.1Confident69.4Low90 Ų9082.2 Ų82.242%0.42142%0.423SS..Hα-helixtrans-71.1-45.1174.8-75.5-176.9167.400110.6D69 S74 K75 E76D69-E72 PolarHBondContact O-N 2.76Å; D69-E72 WeakPolarHBondContact OD1-CB 3.2Å; D69-E72 WeakPolarHBondContact OD1-CG 3.32Å; D69-E72 PolarHBondContact OD1-N 3.43Å; E72-S74 PolarHBondContact O-N 3.45Å; E72-K75 PolarHBondContact O-N 3.11Å; E72-E76 PolarHBondContact O-N 2.91Å
73L74.1Confident67.3Low24 Ų2482.9 Ų82.913%0.12643%0.426CS..Hα-helixtrans-60.2-33.2175.2-86.1153.9000112.9H39 I42 K43 F68 D69H39-L73 WeakPolarHBondContact CD2-CD1 3.38Å; I42-L73 HydrophobicContact CG2-CB 3.93Å; K43-L73 HydrophobicContact CG-CD2 4.44Å; F68-L73 HydrophobicContact CB-CD1 4.02Å; F68-L73 HydrophobicContact CB-CG 4.15Å; D69-L73 PolarHBondContact O-N 3.25Å; D69-L73 VanDerWaalsContact O-N 3.15Å
74S73.1Confident65Low9 Ų981 Ų816%0.06343%0.426CS..Hα-helixtrans-78.3-17.1176.474.30000113.8C70 N71 E72C70-S74 WeakPolarHBondContact O-CB 3.13Å; C70-S74 PolarHBondContact O-N 3.02Å; C70-S74 PolarHBondContact O-OG 3.39Å; N71-S74 PolarHBondContact O-OG 3.35Å; E72-S74 PolarHBondContact O-N 3.45Å
75K67Low62.3Low158 Ų15887 Ų8769%0.68746%0.462SS*.Hα-helixtrans-79.5-31.8174.6-74.7169.2-174.1171.10112.2N71 E72 R77N71-K75 WeakPolarHBondContact O-CG 3.45Å; N71-K75 PolarHBondContact O-N 3.28Å; E72-K75 PolarHBondContact O-N 3.11Å; K75-R77 PolarHBondContact O-N 2.86Å
76E58.6Low59.5Low150 Ų15084.6 Ų84.670%0.70145%0.453SS*.THydrogen-bonded Turntrans-69.5-18.2177.2-70.3-169.416100113.2E72E72-E76 PolarHBondContact O-N 2.91Å
77R52.4Low56.9Low128 Ų12885.1 Ų85.148%0.48346%0.462SS..THydrogen-bonded Turntrans-123.6136178.1-67.2-168.8172.2-170.63.2109.8K43 K75 I79K43-R77 PolarHBondContact O-NH1 3.15Å; K43-R77 PolarHBondContact O-NH2 2.97Å; K75-R77 PolarHBondContact O-N 2.86Å; R77-I79 HydrophobicContact CB-CD1 4.07Å; R77-I79 HydrophobicContact CB-CG1 4.22Å; R77-I79 PolarHBondContact O-N 3.25Å
78T50.3Low54.2Low154 Ų15491.7 Ų91.795%0.94549%0.485SS*.THydrogen-bonded Turntrans-63.670.1-179.450.30000113.1
79I51.4Low51.5Low13 Ų1390 Ų907%0.06749%0.491CS..  trans-105.6-12.3-179-68.3174000111I42 L47 R77 S81 I83I42-I79 HydrophobicContact CG2-CD1 4.18Å; L47-I79 HydrophobicContact CD2-CB 4.42Å; L47-I79 HydrophobicContact CD2-CG1 4.36Å; L47-I79 HydrophobicContact CD2-CG2 3.68Å; R77-I79 HydrophobicContact CB-CD1 4.07Å; R77-I79 HydrophobicContact CB-CG1 4.22Å; R77-I79 PolarHBondContact O-N 3.25Å; I79-S81 PolarHBondContact O-N 3.39Å; I79-I83 HydrophobicContact CG2-CD1 3.63Å; I79-I83 HydrophobicContact CG2-CG1 3.93Å
80D46.2Very low48.9Very low138 Ų13897.2 Ų97.274%0.73852%0.524SS*.THydrogen-bonded Turntrans-58.2-22.2-175.3-95-6.3000115.5
81S41.1Very low46.3Very low112 Ų112104.8 Ų104.878%0.78356%0.563SS**THydrogen-bonded Turntrans-93.7-5.5-169.7108.30000116I79I79-S81 PolarHBondContact O-N 3.39Å
82K41.5Very low43.9Very low140 Ų140111.5 Ų111.561%0.60959%0.589SS**THydrogen-bonded Turntrans-139.29.1-171.5-75.7-170.5-179.4-179.20116.2L47 S84L47-K82 HydrophobicContact CD1-CB 4.47Å; K82-S84 PolarHBondContact O-N 3.09Å
83I40.1Very low41.6Very low50 Ų50113.9 Ų113.926%0.25661%0.605SS.*  trans-75.378.6165.8-56.1173.6000107.3V50 W60 I79 V85V50-I83 HydrophobicContact CG1-CD1 4.4Å; W60-I83 HydrophobicContact CH2-CD1 3.53Å; W60-I83 HydrophobicContact CZ2-CD1 4.1Å; I79-I83 HydrophobicContact CG2-CD1 3.63Å; I79-I83 HydrophobicContact CG2-CG1 3.93Å; I83-V85 PolarHBondContact O-N 3.04Å
84S35.4Very low39Very low77 Ų77116.2 Ų116.254%0.53864%0.635SS.*  trans-62.7115.1164.8-50.50000106.2K82 P86K82-S84 PolarHBondContact O-N 3.09Å; S84-P86 WeakPolarHBondContact O-CD 3.33Å; S84-P86 VanDerWaalsContact O-CG 3.24Å; S84-P86 WeakPolarHBondContact O-CG 3.48Å; S84-P86 VanDerWaalsContact O-N 3.15Å
85V27.4Very low36.5Very low134 Ų134124.4 Ų124.481%0.81267%0.672SS**  trans-69.699.4160.2-177.50000105.3I83 V87I83-V85 PolarHBondContact O-N 3.04Å; V85-V87 PolarHBondContact O-N 2.84Å
86P27.8Very low34.4Very low67 Ų67123.7 Ų123.744%0.43568%0.68SS.*  trans-86.5125.1-169.20.821000108.6S84 M88S84-P86 WeakPolarHBondContact O-CD 3.33Å; S84-P86 VanDerWaalsContact O-CG 3.24Å; S84-P86 WeakPolarHBondContact O-CG 3.48Å; S84-P86 VanDerWaalsContact O-N 3.15Å; P86-M88 PolarHBondContact O-N 3.42Å
87V26.4Very low32.5Very low141 Ų141124.9 Ų124.986%0.85568%0.683SS**  trans-54101.7165.6176.60000108.6V85 G89V85-V87 PolarHBondContact O-N 2.84Å; V87-G89 PolarHBondContact O-N 3.34Å
88M24.4Very low31.1Very low171 Ų171124.9 Ų124.984%0.84270%0.697SS**SBendtrans-69.495.5176.7-126.7-67.9-91.700109.2P86P86-M88 PolarHBondContact O-N 3.42Å
89G25.9Very low29.7Very low46 Ų46124 Ų12447%0.47469%0.687SS.*  trans-158.21.1178.800000118V87V87-G89 PolarHBondContact O-N 3.34Å
90Q29Very low28.2Very low176 Ų176131.4 Ų131.482%0.82272%0.721SS**SBendtrans-138.730.1-166.9-70.2-165.7-18.800118.2
91I25.7Very low27Very low160 Ų160129.6 Ų129.682%0.82172%0.716SS**SBendtrans-113.50.2169.2-59.9179.6000113.7
92F28.6Very low26Very low203 Ų203132.1 Ų132.189%0.8972%0.715SS**SBendtrans-115.310171.1-75.6-73.8000115.4
93N26.7Very low25Very low140 Ų140131 Ų13175%0.74973%0.725SS**SBendtrans-114.8135.5169.4-79.4-17.3000110.4
94G21.1Very low24.1Very low74 Ų74131.6 Ų131.676%0.76374%0.743SS**  trans-59.3147.7-165.800000116.8
95H20.4Very low23.4Very low181 Ų181134.1 Ų134.184%0.83876%0.761SS**  trans28.5100.8153.7-97.157.7000117.7
96V22.1Very low23Very low143 Ų143132.1 Ų132.187%0.86775%0.753SS**  trans-130.8126.6142.3179.20000108.3
97K19.7Very low22.6Very low174 Ų174136.1 Ų136.176%0.75777%0.77SS**  trans-72.2137.1176.8-64.1173.6173.3-178.30110.5
98T22.5Very low22.3Very low128 Ų128134.6 Ų134.679%0.78576%0.761SS**  trans-161.394.9146.745.50000104.7
99D20.4Very low22Very low136 Ų136132.3 Ų132.373%0.72776%0.756SS**  56.7116.891.7-76.6-14.8000113.3
100E20.8Very low21.7Very low168 Ų168137.8 Ų137.879%0.78577%0.774SS**  trans69.5133.2141.1-65.2-172.6-179.900115.8
101T20.4Very low21.2Very low101 Ų101133.2 Ų133.262%0.6276%0.761SS**  cis-170.5152.619.87.80000107.7
102E20.7Very low21Very low165 Ų165132.9 Ų132.977%0.77176%0.761SS**  trans74.8115.5137.8-72.8173.3-175.100122.2
103S20Very low20.7Very low116 Ų116129.7 Ų129.781%0.81176%0.758SS**  61.5115.5126.475.90000116.3
104G20.1Very low20.3Very low63 Ų63131.9 Ų131.965%0.64977%0.766SS**  cis12014942.700000107.8
105S20.6Very low20.3Very low129 Ų129131.6 Ų131.690%0.90276%0.763SS**  trans73.7143.8174.978.20000117
106S19.6Very low20.3Very low93 Ų93130.4 Ų130.465%0.6576%0.763SS**  cis171.2160.4-25.6-162.20000103
107L19.5Very low20.2Very low150 Ų150130.6 Ų130.679%0.78576%0.759SS**  trans75.2139.2156.4-56.8162.2000116.4
108T19.4Very low20.2Very low110 Ų110126.6 Ų126.668%0.67576%0.759SS**  cis-177.1137.3-14.516.10000104.8
109V18.5Very low20.2Very low122 Ų122125.7 Ų125.774%0.73976%0.757SS**  32.8120.8129.6-172.30000119
110L19.9Very low20.2Very low162 Ų162128 Ų12885%0.84876%0.764SS**  trans-164.196133.9-86.4178.2000105.7
111S19.1Very low20Very low79 Ų79126.4 Ų126.455%0.55277%0.765SS**  48.21268771.90000115.7
112D20.8Very low20.1Very low153 Ų153127.3 Ų127.382%0.81877%0.773SS**  trans106.5142.3148.4-62.9-22.9000121.1
113V22.9Very low19.9Very low137 Ų137125.3 Ų125.383%0.8377%0.772SS**  trans11486.9161.5-165.10000115.1
114M18.8Very low19.9Very low186 Ų186128.7 Ų128.792%0.91678%0.777SS**  trans-47.1164.8154.3-56.9175.3-65.200115.2
115G20.7Very low19.8Very low68 Ų68133.6 Ų133.670%0.70179%0.789SS**  trans139.877.5159.600000111.3
116N19.7Very low19.8Very low155 Ų155130.9 Ų130.983%0.82978%0.781SS**  62.2145.583.9-898000116.7
117D21Very low19.9Very low147 Ų147134.9 Ų134.979%0.78680%0.795SS**  trans91.299.8169.9-54.1-20.6000114.6
118A19.2Very low19.9Very low91 Ų91130.7 Ų130.775%0.75279%0.788SS**  cis63.194.435.900000114.4
119S21.4Very low20Very low108 Ų108134.5 Ų134.576%0.75580%0.798SS**  trans157.7141.2152.544.80000108
120Q20.4Very low20.1Very low186 Ų186134.5 Ų134.587%0.86980%0.798SS**  cis-162.71447.4-112.7165.319.100107.7
121V18.3Very low20.1Very low133 Ų133132.3 Ų132.381%0.80679%0.791SS**PPolyproline II helixtrans-84.1139.1169.91770000109
122P20.6Very low20.2Very low120 Ų120135.4 Ų135.478%0.77980%0.8SS**PPolyproline II helixtrans-101.1120.5161.328.5-16.2000111.3
123T18.4Very low20.1Very low124 Ų124133.5 Ų133.576%0.76179%0.794SS**PPolyproline II helixtrans-71.4135.116645.50000111.6
124M19Very low20.1Very low187 Ų187132 Ų13292%0.92179%0.787SS**  trans-133.5104.4162.3-91.2-81.9-17500109.3
125N18.7Very low20.3Very low166 Ų166129.2 Ų129.289%0.88878%0.782SS**  trans-71.3139.6162.4-79-23.5000109.5
126G20.6Very low20.4Very low72 Ų72130.1 Ų130.174%0.74278%0.783SS**  trans178.396.1170.500000112.8G128G126-G128 PolarHBondContact O-N 2.89Å
127N20.2Very low20.6Very low177 Ų177127.5 Ų127.595%0.94778%0.777SS**  trans-53.4100.8171.1-69.3-15.3000111.2
128G20.9Very low20.9Very low61 Ų61127.4 Ų127.463%0.62978%0.776SS**  trans-111.498.9170.200000109.7G126 V130G126-G128 PolarHBondContact O-N 2.89Å; G128-V130 PolarHBondContact O-N 2.84Å
129H20.4Very low21.1Very low191 Ų191129.4 Ų129.488%0.88478%0.779SS**  trans-57.7100.1164.4-102.1-85.7000108.5V131H129-V131 PolarHBondContact O-N 3.5Å
130V21.3Very low21.5Very low121 Ų121127.2 Ų127.273%0.73376%0.764SS**  trans-73.895.3172-178.30000107.1G128 I132G128-V130 PolarHBondContact O-N 2.84Å; V130-I132 VanDerWaalsContact C-N 3.31Å; V130-I132 HydrophobicContact CG1-CG1 3.91Å; V130-I132 PolarHBondContact O-N 3.46Å
131V19Very low21.7Very low117 Ų117127.9 Ų127.971%0.70977%0.767SS**  trans-67.396.2165.1177.60000106.5H129 T133H129-V131 PolarHBondContact O-N 3.5Å; V131-T133 VanDerWaalsContact C-N 3.26Å; V131-T133 HydrophobicContact CG1-CG2 4.41Å; V131-T133 PolarHBondContact O-N 3.46Å
132I20.9Very low22.1Very low144 Ų144129.4 Ų129.474%0.73877%0.765SS**  trans-72.288.4169.3-57.1175.7000106.4V130 P134V130-I132 VanDerWaalsContact C-N 3.31Å; V130-I132 HydrophobicContact CG1-CG1 3.91Å; V130-I132 PolarHBondContact O-N 3.46Å; I132-P134 WeakPolarHBondContact O-CD 3.38Å
133T19.3Very low22.5Very low112 Ų112127.3 Ų127.369%0.68775%0.754SS**PPolyproline II helixtrans-63.112215933.50000107.6V131V131-T133 VanDerWaalsContact C-N 3.26Å; V131-T133 HydrophobicContact CG1-CG2 4.41Å; V131-T133 PolarHBondContact O-N 3.46Å
134P22.5Very low23.1Very low106 Ų106128.6 Ų128.669%0.68876%0.755SS**PPolyproline II helixtrans-57.1143.7170.6-10.121.1000108.5I132 A136I132-P134 WeakPolarHBondContact O-CD 3.38Å; P134-A136 PolarHBondContact O-N 2.9Å; P134-A136 VanDerWaalsContact O-N 3.15Å
135P23.6Very low23.5Very low127 Ų127126.6 Ų126.683%0.82574%0.743SS**PPolyproline II helixtrans-52.8127.9-177.420.2-30.1000109.1S137P135-S137 PolarHBondContact O-N 3.44Å
136A23.7Very low24.2Very low87 Ų87121.4 Ų121.472%0.71972%0.724SS**  trans-45.1130.9-178.300000109.4P134 L138P134-A136 PolarHBondContact O-N 2.9Å; P134-A136 VanDerWaalsContact O-N 3.15Å; A136-L138 PolarHBondContact O-N 3.05Å
137S23.9Very low24.8Very low100 Ų100127.2 Ų127.270%0.69973%0.728SS**  trans-27.7111.7164.9-23.20000109.4P135 T139P135-S137 PolarHBondContact O-N 3.44Å; S137-T139 PolarHBondContact O-N 3.42Å
138L26.4Very low25.7Very low145 Ų145123.7 Ų123.776%0.75971%0.713SS**  trans-63.575167.2-80.8152.1000107.7A136 S140A136-L138 PolarHBondContact O-N 3.05Å; L138-S140 PolarHBondContact O-N 3.07Å
139T23.9Very low27.1Very low133 Ų133123.6 Ų123.682%0.81670%0.7SS**  trans-85.365.5162.152.50000107S137S137-T139 PolarHBondContact O-N 3.42Å
140S28.7Very low28.4Very low63 Ų63122.6 Ų122.644%0.44170%0.696SS.*SBendtrans-152.5121.5155.658.50000104.6L138 Q142L138-S140 PolarHBondContact O-N 3.07Å; S140-Q142 PolarHBondContact O-N 3.49Å
141E26.1Very low30.1Very low200 Ų200118.8 Ų118.894%0.93567%0.671SS**  trans-63.936.6176.5-64177.1140.100113.1S143E141-S143 PolarHBondContact O-N 3.38Å
142Q25.7Very low32.2Very low165 Ų165120.1 Ų120.177%0.77167%0.667SS**  trans-77.577.7155.7-66.1-171.7-0.300106.6S140 L144S140-Q142 PolarHBondContact O-N 3.49Å; Q142-L144 PolarHBondContact O-N 3.43Å
143S30.2Very low34.1Very low76 Ų76115.8 Ų115.853%0.53165%0.653SS.*  trans-37.6123.7158.953.30000109.2E141 Q145E141-S143 PolarHBondContact O-N 3.38Å; S143-Q145 PolarHBondContact O-N 3.49Å
144L30.4Very low36.3Very low151 Ų151115.8 Ų115.879%0.79165%0.649SS**  trans-6547.2158-69.9153.6000109.6Q142 A146Q142-L144 PolarHBondContact O-N 3.43Å; L144-A146 VanDerWaalsContact C-N 3.29Å; L144-A146 PolarHBondContact O-N 3.13Å
145Q26.8Very low38.8Very low144 Ų144112.4 Ų112.467%0.67362%0.624SS**  trans-56.8110.7146.9-77.6-178.9-5.500103S143 K147S143-Q145 PolarHBondContact O-N 3.49Å; Q145-K147 PolarHBondContact O-N 3.35Å
146A33.4Very low41.6Very low58 Ų58107.3 Ų107.348%0.47959%0.588SS.*  trans-42.3113166.300000105.3L144 V148L144-A146 VanDerWaalsContact C-N 3.29Å; L144-A146 PolarHBondContact O-N 3.13Å; A146-V148 PolarHBondContact O-N 3.29Å
147K33.2Very low44.5Very low193 Ų193106.2 Ų106.284%0.83957%0.566SS**  trans-53.2107.1164.3-92179174.6175.10102.3Q145 V149Q145-K147 PolarHBondContact O-N 3.35Å; K147-V149 PolarHBondContact O-N 3.08Å
148V40Very low47.5Very low103 Ų103105.3 Ų105.362%0.62455%0.547SS*.  trans-55.7104.7169175.20000102.6A146 E150A146-V148 PolarHBondContact O-N 3.29Å; V148-E150 PolarHBondContact O-N 3.08Å
149V49.4Very low50.5Low59 Ų5998.6 Ų98.636%0.35851%0.512SS..  trans-67.498.3172.3177.20000102.6K147 L151 L565K147-V149 PolarHBondContact O-N 3.08Å; V149-L151 PolarHBondContact O-N 3.39Å; V149-L565 HydrophobicContact CB-CD2 4.4Å; V149-L565 HydrophobicContact CG1-CD2 4.37Å
150E48.6Very low53.8Low171 Ų17192.5 Ų92.580%0.79948%0.475SS*.  trans-63.392.4168.7-75.4-174.3170.400106.1V148 K152V148-E150 PolarHBondContact O-N 3.08Å; E150-K152 PolarHBondContact O-N 2.84Å; E150-K152 VanDerWaalsContact O-N 3.11Å
151L56.2Low56.9Low41 Ų4189.8 Ų89.822%0.21546%0.455CS..  trans-54118.8167.5-80.1155.1000106.3V149 E155 R158 M159 L565V149-L151 PolarHBondContact O-N 3.39Å; L151-E155 HydrophobicContact CD2-CB 4.12Å; L151-R158 HydrophobicContact CD2-CB 4.4Å; L151-M159 HydrophobicContact CD1-CG 3.79Å; L151-M159 HydrophobicContact CD1-SD 3.64Å; L151-L565 HydrophobicContact CD1-CD2 4.1Å; L151-L565 HydrophobicContact CD2-CD1 4.3Å; L151-L565 HydrophobicContact CD2-CD2 4.14Å; L151-L565 HydrophobicContact CG-CD2 4.16Å
152K63.8Low60.2Low144 Ų14480.4 Ų80.463%0.62641%0.411SS*.  trans-56.6147168.8-65.4179.3179.9176.40107.8E150 D154 E155E150-K152 PolarHBondContact O-N 2.84Å; E150-K152 VanDerWaalsContact O-N 3.11Å; K152-D154 PolarHBondContact O-N 3.4Å; K152-E155 HydrophobicContact CB-CB 4.42Å; K152-E155 HydrophobicContact CB-CG 4.16Å; K152-E155 WeakPolarHBondContact O-CB 3.35Å; K152-E155 PolarHBondContact O-N 3.41Å
153A60.1Low63.5Low54 Ų5475 Ų7545%0.44639%0.386SS..G310 helixtrans-51.4-32.6178.900000112.3E155A153-E155 VanDerWaalsContact C-N 3.31Å; A153-E155 PolarHBondContact O-N 2.99Å
154D65.3Low66.7Low111 Ų11172 Ų7259%0.59437%0.365SS*.G310 helixtrans-78.7-9.4-179.9-55.3-34.4000114.3K152 Y157 Q292K152-D154 PolarHBondContact O-N 3.4Å; D154-Y157 VanDerWaalsContact O-CD1 3.3Å; D154-Y157 WeakPolarHBondContact O-CD1 3.48Å; D154-Y157 WeakPolarHBondContact O-CE1 3.23Å; D154-Q292 PolarHBondContact OD1-NE2 3.02Å
155E75.4Confident69.8Low35 Ų3567 Ų6716%0.16434%0.337CS..G310 helixtrans-100.311-174-75.4-172.8178.600113.7L151 K152 A153 Y157 R158L151-E155 HydrophobicContact CD2-CB 4.12Å; K152-E155 HydrophobicContact CB-CB 4.42Å; K152-E155 HydrophobicContact CB-CG 4.16Å; K152-E155 WeakPolarHBondContact O-CB 3.35Å; K152-E155 PolarHBondContact O-N 3.41Å; A153-E155 VanDerWaalsContact C-N 3.31Å; A153-E155 PolarHBondContact O-N 2.99Å; E155-Y157 PolarHBondContact O-N 3.25Å; E155-R158 WeakPolarHBondContact O-CB 3.35Å; E155-R158 WeakPolarHBondContact O-CG 3.47Å; E155-R158 PolarHBondContact O-N 3.36Å; E155-R158 IonicContact OE1-CZ 3.88Å; E155-R158 IonicContact OE1-NH1 3.58Å; E155-R158 PolarHBondContact OE1-NH1 3.38Å; E155-R158 IonicContact OE1-NH2 2.69Å; E155-R158 PolarHBondContact OE1-NH2 3.2Å; E155-R158 IonicContact OE2-CZ 2.76Å; E155-R158 VanDerWaalsContact OE2-CZ 3.32Å; E155-R158 IonicContact OE2-NE 2.78Å; E155-R158 IonicContact OE2-NH1 3.64Å; E155-R158 PolarHBondContact OE2-NH1 3.33Å
156W81.5Confident73Confident21 Ų2163.9 Ų63.98%0.0832%0.322CS..G310 helixtrans-52.5-31.2179.967.1-97.6000113.2R158 M159 L160 M279 L282 C283 L295 P296 L298W156-R158 PolarHBondContact O-N 3.16Å; W156-R158 VanDerWaalsContact O-N 3.16Å; W156-M159 VanDerWaalsContact O-CB 3.25Å; W156-M159 WeakPolarHBondContact O-CB 3.38Å; W156-M159 PolarHBondContact O-N 3.08Å; W156-L160 HydrophobicContact CH2-CD1 4.43Å; W156-L160 HydrophobicContact CZ3-CD1 3.9Å; W156-L160 HydrophobicContact CZ3-CD2 4.19Å; W156-L160 HydrophobicContact CZ3-CG 4.05Å; W156-M279 HydrophobicContact CH2-CG 4.27Å; W156-M279 HydrophobicContact CZ3-CB 4.45Å; W156-M279 HydrophobicContact CZ3-CG 4.17Å; W156-L282 HydrophobicContact CE3-CB 4.22Å; W156-C283 WeakPolarHBondContact CH2-SG 3.49Å; W156-C283 WeakPolarHBondContact CZ2-SG 3.27Å; W156-C283 WeakPolarHBondContact CZ3-SG 3.47Å; W156-L295 HydrophobicContact CH2-CD1 3.84Å; W156-L295 HydrophobicContact CZ2-CD1 3.95Å; W156-P296 HydrophobicContact CZ2-CG 3.88Å; W156-L298 HydrophobicContact CH2-CD2 3.77Å; W156-L298 HydrophobicContact CZ2-CD2 3.71Å
157Y85.7Confident75.9Confident64 Ų6463.6 Ų63.625%0.25131%0.313SS..G310 helixtrans-65.1-18.8-178.859.8-98.4000113.1D154 E155 M159 L160 L167 I169D154-Y157 VanDerWaalsContact O-CD1 3.3Å; D154-Y157 WeakPolarHBondContact O-CD1 3.48Å; D154-Y157 WeakPolarHBondContact O-CE1 3.23Å; E155-Y157 PolarHBondContact O-N 3.25Å; Y157-M159 PolarHBondContact O-N 2.88Å; Y157-L160 WeakPolarHBondContact O-CB 3.44Å; Y157-L160 PolarHBondContact O-N 2.92Å; Y157-L167 HydrophobicContact CD2-CD2 3.62Å; Y157-L167 HydrophobicContact CE2-CD2 4.5Å; Y157-L167 HydrophobicContact CG-CD2 3.75Å; Y157-I169 HydrophobicContact CD1-CD1 3.31Å; Y157-I169 HydrophobicContact CD2-CD1 4.49Å; Y157-I169 HydrophobicContact CE1-CD1 3.51Å; Y157-I169 HydrophobicContact CG-CD1 3.86Å
158R87.3Confident78.7Confident80 Ų8057.1 Ų57.130%0.30229%0.292SS..G310 helixtrans-67.5-18.1172.6-63.1175.9173.6-167.1-9.4112.5L151 E155 W156 L565L151-R158 HydrophobicContact CD2-CB 4.4Å; E155-R158 WeakPolarHBondContact O-CB 3.35Å; E155-R158 WeakPolarHBondContact O-CG 3.47Å; E155-R158 PolarHBondContact O-N 3.36Å; E155-R158 IonicContact OE1-CZ 3.88Å; E155-R158 IonicContact OE1-NH1 3.58Å; E155-R158 PolarHBondContact OE1-NH1 3.38Å; E155-R158 IonicContact OE1-NH2 2.69Å; E155-R158 PolarHBondContact OE1-NH2 3.2Å; E155-R158 IonicContact OE2-CZ 2.76Å; E155-R158 VanDerWaalsContact OE2-CZ 3.32Å; E155-R158 IonicContact OE2-NE 2.78Å; E155-R158 IonicContact OE2-NH1 3.64Å; E155-R158 PolarHBondContact OE2-NH1 3.33Å; W156-R158 PolarHBondContact O-N 3.16Å; W156-R158 VanDerWaalsContact O-N 3.16Å; R158-L565 HydrophobicContact CB-CD1 3.91Å
159M88.9Confident80.9Confident5 Ų555.1 Ų55.13%0.02528%0.277CS..G310 helixtrans-87.1-11.4176.2-63.7-64.5-59.400113.3L151 W156 Y157 W161 L282 L565 F568 I569 D572 H573L151-M159 HydrophobicContact CD1-CG 3.79Å; L151-M159 HydrophobicContact CD1-SD 3.64Å; W156-M159 VanDerWaalsContact O-CB 3.25Å; W156-M159 WeakPolarHBondContact O-CB 3.38Å; W156-M159 PolarHBondContact O-N 3.08Å; Y157-M159 PolarHBondContact O-N 2.88Å; M159-W161 PolarHBondContact O-N 3.25Å; M159-L282 HydrophobicContact CB-CD1 3.89Å; M159-L282 HydrophobicContact CB-CD2 3.84Å; M159-L565 HydrophobicContact SD-CD1 4.48Å; M159-L565 HydrophobicContact SD-CD2 4.49Å; M159-F568 VanDerWaalsContact CE-C 3.49Å; M159-F568 HydrophobicContact CE-CB 3.64Å; M159-F568 HydrophobicContact SD-CB 4.19Å; M159-I569 HydrophobicContact CE-CG1 3.95Å; M159-I569 HydrophobicContact SD-CG1 4.05Å; M159-D572 HydrophobicContact CE-CB 4.29Å; M159-H573 PolarHBondContact O-NE2 3.42Å
160L92.4Very high82.5Confident5 Ų557.8 Ų57.83%0.02629%0.285CS..  trans-61.2127173.9-71171.8000109.2W156 Y157 Q278 M279 L282 I300W156-L160 HydrophobicContact CH2-CD1 4.43Å; W156-L160 HydrophobicContact CZ3-CD1 3.9Å; W156-L160 HydrophobicContact CZ3-CD2 4.19Å; W156-L160 HydrophobicContact CZ3-CG 4.05Å; Y157-L160 WeakPolarHBondContact O-CB 3.44Å; Y157-L160 PolarHBondContact O-N 2.92Å; L160-Q278 HydrophobicContact CD2-CB 3.92Å; L160-M279 HydrophobicContact CD1-CG 4.33Å; L160-M279 HydrophobicContact CD2-CG 3.73Å; L160-L282 HydrophobicContact CD2-CD1 3.86Å; L160-L282 HydrophobicContact CG-CD1 4.27Å; L160-I300 HydrophobicContact CD1-CD1 4.15Å
161W94.9Very high83.4Confident6 Ų654.4 Ų54.42%0.02328%0.28CS..SBendtrans-142.9128.6-176.4-160.4-100.9000112.6M159 Q163 Q278 V546 V557 F562 I569 H573M159-W161 PolarHBondContact O-N 3.25Å; W161-Q163 HydrophobicContact CE3-CB 4.38Å; W161-Q163 HydrophobicContact CZ3-CB 4.21Å; W161-Q278 PolarHBondContact O-NE2 3.15Å; W161-Q278 PolarHBondContact O-OE1 3Å; W161-Q278 VanDerWaalsContact O-OE1 3.05Å; W161-V546 PolarHBondContact NE1-O 3.49Å; W161-V557 HydrophobicContact CH2-CG1 4.11Å; W161-V557 HydrophobicContact CH2-CG2 4.27Å; W161-V557 HydrophobicContact CZ3-CG1 4.19Å; W161-V557 HydrophobicContact CZ3-CG2 4.37Å; W161-F562 HydrophobicContact CD2-CE2 4.07Å; W161-F562 AromaticContact CE2-CE2 3.68Å; W161-F562 AromaticContact CE3-CD2 3.98Å; W161-F562 HydrophobicContact CE3-CD2 3.98Å; W161-F562 AromaticContact CE3-CE2 3.96Å; W161-F562 HydrophobicContact CE3-CE2 3.96Å; W161-F562 HydrophobicContact CH2-CD1 4.23Å; W161-F562 AromaticContact CH2-CD2 3.11Å; W161-F562 HydrophobicContact CH2-CD2 3.11Å; W161-F562 HydrophobicContact CH2-CE1 4.2Å; W161-F562 AromaticContact CH2-CE2 3.07Å; W161-F562 HydrophobicContact CH2-CE2 3.07Å; W161-F562 AromaticContact CH2-CG 3.7Å; W161-F562 HydrophobicContact CH2-CG 3.7Å; W161-F562 AromaticContact CH2-CZ 3.63Å; W161-F562 HydrophobicContact CH2-CZ 3.63Å; W161-F562 AromaticContact CZ2-CD2 3.76Å; W161-F562 HydrophobicContact CZ2-CD2 3.76Å; W161-F562 HydrophobicContact CZ2-CE1 4.27Å; W161-F562 AromaticContact CZ2-CE2 3.16Å; W161-F562 HydrophobicContact CZ2-CE2 3.16Å; W161-F562 HydrophobicContact CZ2-CG 4.49Å; W161-F562 AromaticContact CZ2-CZ 3.43Å; W161-F562 HydrophobicContact CZ2-CZ 3.43Å; W161-F562 VanDerWaalsContact CZ2-CZ 3.43Å; W161-F562 AromaticContact CZ3-CD2 3.23Å; W161-F562 HydrophobicContact CZ3-CD2 3.23Å; W161-F562 AromaticContact CZ3-CE2 3.49Å; W161-F562 HydrophobicContact CZ3-CE2 3.49Å; W161-F562 VanDerWaalsContact CZ3-CE2 3.49Å; W161-F562 HydrophobicContact CZ3-CG 4.05Å; W161-F562 HydrophobicContact CZ3-CZ 4.46Å; W161-I569 HydrophobicContact CB-CG2 3.6Å; W161-I569 HydrophobicContact CD2-CG2 3.89Å; W161-I569 HydrophobicContact CE3-CD1 4.1Å; W161-I569 HydrophobicContact CE3-CG2 4.42Å; W161-I569 HydrophobicContact CG-CG2 3.5Å; W161-I569 VanDerWaalsContact CG-CG2 3.5Å; W161-H573 WeakPolarHBondContact CB-NE2 3.4Å
162P95.9Very high83.7Confident3 Ų360 Ų602%0.01931%0.31CS..SBendcis-60.7149.8-1.8-26.236.8000114.3L336 K337 W553P162-L336 WeakPolarHBondContact CG-O 3.48Å; P162-K337 HydrophobicContact CG-CD 4.26Å; P162-K337 HydrophobicContact CG-CG 4.46Å; P162-W553 HydrophobicContact CB-CB 3.5Å; P162-W553 VanDerWaalsContact CB-CB 3.5Å; P162-W553 HydrophobicContact CB-CG 3.56Å; P162-W553 HydrophobicContact CG-CB 3.78Å; P162-W553 HydrophobicContact CG-CG 3.97Å
163Q95.1Very high83.5Confident52 Ų5255.1 Ų55.124%0.24330%0.295CS..PPolyproline II helixtrans-60.9127179.5-169.8179.542.300109.7W161 N554 V557W161-Q163 HydrophobicContact CE3-CB 4.38Å; W161-Q163 HydrophobicContact CZ3-CB 4.21Å; Q163-N554 WeakPolarHBondContact O-CB 3.4Å; Q163-N554 PolarHBondContact O-ND2 2.85Å; Q163-V557 HydrophobicContact CB-CG2 3.88Å
164P96.4Very high83.9Confident13 Ų1358.8 Ų58.88%0.08432%0.317CS..PPolyproline II helixtrans-63.6147.1-179.624.7-32.9000111.4L167 I300 N554P164-L167 HydrophobicContact CG-CB 4.2Å; P164-I300 HydrophobicContact CB-CG2 3.78Å; P164-N554 PolarHBondContact O-ND2 2.73Å
165Q95.1Very high84.4Confident44 Ų4458 Ų5821%0.20631%0.31CS..SBendtrans-62.2-44.1177.9-65.5-78.4-13.800112.2D302 W303 S305 W553Q165-D302 WeakPolarHBondContact CG-OD1 3.4Å; Q165-D302 PolarHBondContact N-OD1 3.08Å; Q165-W303 HydrophobicContact CB-CD2 4.08Å; Q165-W303 HydrophobicContact CB-CE3 4.26Å; Q165-W303 HydrophobicContact CB-CH2 3.9Å; Q165-W303 HydrophobicContact CB-CZ2 3.66Å; Q165-W303 HydrophobicContact CB-CZ3 4.17Å; Q165-W303 HydrophobicContact CG-CD2 3.9Å; Q165-W303 HydrophobicContact CG-CE3 4.49Å; Q165-W303 HydrophobicContact CG-CG 4.12Å; Q165-W303 HydrophobicContact CG-CZ2 4.05Å; Q165-W303 WeakPolarHBondContact CG-O 3.21Å; Q165-W303 PolarHBondContact NE2-O 2.69Å; Q165-S305 PolarHBondContact NE2-OG 3.28Å; Q165-W553 PolarHBondContact NE2-O 3.23Å
166Q94.7Very high84.7Confident79 Ų7957.7 Ų57.737%0.36931%0.313SS..EExtended strand (participates in β ladder)trans-135.6124.7177.4-63.9-176.5-9.300110.3I300 R301 W303Q166-I300 WeakPolarHBondContact O-CA 3.47Å; Q166-R301 HydrophobicContact CB-CB 4.26Å; Q166-R301 WeakPolarHBondContact CB-O 3.44Å; Q166-R301 PolarHBondContact N-O 3.46Å; Q166-R301 VanDerWaalsContact N-O 3.09Å; Q166-R301 PolarHBondContact O-N 3.09Å; Q166-W303 HydrophobicContact CG-CH2 3.76Å; Q166-W303 HydrophobicContact CG-CZ3 4.28Å
167L93.9Very high84.9Confident53 Ų5356.8 Ų56.828%0.27731%0.31SS..EExtended strand (participates in β ladder)trans-129.2122.9173.6171.866.8000108.2Y157 P164 I169 L298 I300Y157-L167 HydrophobicContact CD2-CD2 3.62Å; Y157-L167 HydrophobicContact CE2-CD2 4.5Å; Y157-L167 HydrophobicContact CG-CD2 3.75Å; P164-L167 HydrophobicContact CG-CB 4.2Å; L167-I169 HydrophobicContact CD1-CG1 4.13Å; L167-I169 HydrophobicContact CD2-CD1 4.16Å; L167-I169 HydrophobicContact CD2-CG1 4.4Å; L167-I169 HydrophobicContact CG-CD1 4.41Å; L167-I169 HydrophobicContact CG-CG1 4.11Å; L167-L298 HydrophobicContact CD1-CD1 4.19Å; L167-I300 HydrophobicContact CD1-CD1 4.18Å; L167-I300 HydrophobicContact CD1-CG1 3.52Å
168S91.7Very high84.7Confident57 Ų5755.9 Ų55.940%0.39931%0.313SS..EExtended strand (participates in β ladder)trans-119.6120.8171.7580000109.4L298 R299S168-L298 CarbonylContact O-C 3.51Å; S168-L298 VanDerWaalsContact O-CA 3.23Å; S168-L298 WeakPolarHBondContact O-CA 3.43Å; S168-L298 WeakPolarHBondContact O-CB 3.49Å; S168-R299 PolarHBondContact N-O 2.9Å; S168-R299 PolarHBondContact O-N 2.76Å; S168-R299 PolarHBondContact OG-O 2.94Å
169I87.4Confident84.3Confident61 Ų6153.6 Ų53.631%0.31331%0.306SS..EExtended strand (participates in β ladder)trans-107.1132.1178.3-57.9172.2000108.2Y157 L167 S171 P296 L298Y157-I169 HydrophobicContact CD1-CD1 3.31Å; Y157-I169 HydrophobicContact CD2-CD1 4.49Å; Y157-I169 HydrophobicContact CE1-CD1 3.51Å; Y157-I169 HydrophobicContact CG-CD1 3.86Å; L167-I169 HydrophobicContact CD1-CG1 4.13Å; L167-I169 HydrophobicContact CD2-CD1 4.16Å; L167-I169 HydrophobicContact CD2-CG1 4.4Å; L167-I169 HydrophobicContact CG-CD1 4.41Å; L167-I169 HydrophobicContact CG-CG1 4.11Å; I169-S171 PolarHBondContact O-N 3.5Å; I169-P296 HydrophobicContact CG2-CB 4.46Å; I169-L298 HydrophobicContact CG1-CB 4.23Å
170H83.4Confident83.4Confident114 Ų11459 Ų5953%0.52834%0.339SS..  trans-92.388.5174.2-62.5-72.4000108.9D172 L297H170-D172 PolarHBondContact O-N 3.05Å; H170-L297 HydrophobicContact CB-CB 4.27Å; H170-L297 PolarHBondContact N-O 3.42Å
171S66.1Low82.5Confident100 Ų10063.5 Ų63.570%0.69936%0.363SS*.THydrogen-bonded Turntrans-64.8-23.3-176.749.30000114.6I169 S173I169-S171 PolarHBondContact O-N 3.5Å; S171-S173 PolarHBondContact O-N 3.26Å
172D62.1Low81.8Confident158 Ų15867 Ų6785%0.84539%0.387SS*.THydrogen-bonded Turntrans-87.5-3.7-164.2-61.6-6.4000113.8H170H170-D172 PolarHBondContact O-N 3.05Å
173S60Low81.3Confident42 Ų4271.9 Ų71.929%0.29441%0.408SS..  trans-93.5125.1179.862.60000111.5S171 Q175 L297S171-S173 PolarHBondContact O-N 3.26Å; S173-Q175 PolarHBondContact O-N 3.44Å; S173-Q175 VanDerWaalsContact O-N 3.09Å; S173-Q175 PolarHBondContact OG-O 2.92Å; S173-L297 WeakPolarHBondContact OG-CD1 3.33Å
174S68.4Low81Confident132 Ų13269.6 Ų69.692%0.92340%0.397SS*.SBendtrans-64-4.3162.155.30000113.3
175Q76.6Confident80.7Confident93 Ų9371 Ų7144%0.43540%0.402SS..  trans-88.4142.4178.1-63.4177.3-24.300110.8S173 E256 L297S173-Q175 PolarHBondContact O-N 3.44Å; S173-Q175 VanDerWaalsContact O-N 3.09Å; S173-Q175 PolarHBondContact OG-O 2.92Å; Q175-E256 HydrophobicContact CB-CG 4.42Å; Q175-E256 PolarHBondContact NE2-OE2 3.47Å; Q175-L297 HydrophobicContact CB-CD1 4.12Å
176A82.2Confident80.6Confident29 Ų2969 Ų6924%0.2439%0.392CS..EExtended strand (participates in β ladder)trans-151.4153.6176.100000109.5S178 S294 L295A176-S178 PolarHBondContact O-N 3.29Å; A176-S294 WeakPolarHBondContact CB-OG 3.23Å; A176-L295 CarbonylContact C-O 3.6Å; A176-L295 WeakPolarHBondContact CB-O 3.41Å
177F84.9Confident80.5Confident2 Ų267.2 Ų67.21%0.00938%0.383CS..EExtended strand (participates in β ladder)trans-75.8106.3174.5179.2-87.9000108.9M179 P233 V254 K255 I259 S294 L295F177-M179 HydrophobicContact CE1-CB 4.44Å; F177-P233 HydrophobicContact CE1-CB 4.28Å; F177-P233 HydrophobicContact CE2-CB 3.69Å; F177-P233 HydrophobicContact CZ-CB 3.53Å; F177-V254 HydrophobicContact CB-CG1 3.66Å; F177-V254 HydrophobicContact CG-CG1 4.33Å; F177-K255 WeakPolarHBondContact CD2-O 3.49Å; F177-I259 HydrophobicContact CD1-CD1 3.89Å; F177-I259 HydrophobicContact CD1-CG1 4.31Å; F177-I259 HydrophobicContact CD2-CD1 4.41Å; F177-I259 HydrophobicContact CD2-CG1 3.95Å; F177-I259 HydrophobicContact CE1-CD1 3.6Å; F177-I259 HydrophobicContact CE1-CG1 4.16Å; F177-I259 HydrophobicContact CE2-CD1 4.13Å; F177-I259 HydrophobicContact CE2-CG1 3.76Å; F177-I259 HydrophobicContact CG-CD1 4.28Å; F177-I259 HydrophobicContact CG-CG1 4.21Å; F177-I259 HydrophobicContact CZ-CD1 3.72Å; F177-I259 HydrophobicContact CZ-CG1 3.87Å; F177-S294 CarbonylContact O-C 3.56Å; F177-S294 WeakPolarHBondContact O-CA 3.41Å; F177-S294 WeakPolarHBondContact O-CB 3.43Å; F177-L295 HydrophobicContact CB-CB 4.25Å; F177-L295 HydrophobicContact CD1-CB 4.46Å; F177-L295 PolarHBondContact N-O 3.34Å; F177-L295 PolarHBondContact O-N 3.23Å
178S82.1Confident80.4Confident45 Ų4565 Ų6532%0.31537%0.371SS..  trans-101.9130.1177.4-1730000110.7A176 P233 A293A176-S178 PolarHBondContact O-N 3.29Å; S178-P233 WeakPolarHBondContact O-CG 3.47Å; S178-A293 PolarHBondContact OG-O 3.32Å
179M77.3Confident80.4Confident32 Ų3262.6 Ų62.616%0.15835%0.353CS..  trans-101.397.5175.1-170.1176.571.400108.3F177 D181 V215 V280 L284F177-M179 HydrophobicContact CE1-CB 4.44Å; M179-D181 VanDerWaalsContact CG-O 3.29Å; M179-D181 WeakPolarHBondContact CG-O 3.38Å; M179-V215 HydrophobicContact CE-CG2 4Å; M179-V280 HydrophobicContact CE-CG1 4.35Å; M179-L284 HydrophobicContact CB-CD1 4.01Å; M179-L284 HydrophobicContact CE-CD1 4.15Å
180V70.2Confident80.3Confident119 Ų11962.8 Ų62.872%0.72136%0.36SS*.  trans-77.6-39.3-176-176.90000111.7
181D74.1Confident80.5Confident100 Ų10060.6 Ų60.654%0.53535%0.352SS..SBendtrans-105.4145.6178-66.9-41.1000110.5M179 K183M179-D181 VanDerWaalsContact CG-O 3.29Å; M179-D181 WeakPolarHBondContact CG-O 3.38Å; D181-K183 PolarHBondContact O-N 2.91Å
182P79.9Confident81.5Confident79 Ų7957 Ų5751%0.51333%0.327SS..SBendtrans-73.333.817434.1-37.2000112.2V215 E216P182-V215 WeakPolarHBondContact O-CA 3.26Å; P182-E216 PolarHBondContact O-N 3.44Å
183K85.6Confident82.9Confident106 Ų10653.8 Ų53.846%0.46131%0.313SS..EExtended strand (participates in β ladder)trans-124.3117.9180-61-164.9-177.9-124.90109.8D181 E216D181-K183 PolarHBondContact O-N 2.91Å; K183-E216 CarbonylContact C-O 3.54Å; K183-E216 WeakPolarHBondContact CA-O 3.47Å; K183-E216 WeakPolarHBondContact CE-OE2 3.19Å; K183-E216 HydrophobicContact CG-CB 4.3Å; K183-E216 IonicContact NZ-OE1 2.63Å; K183-E216 IonicContact NZ-OE2 3.57Å; K183-E216 PolarHBondContact NZ-OE2 3.48Å
184L88.8Confident84.3Confident4 Ų453 Ų532%0.02131%0.307CS..EExtended strand (participates in β ladder)trans-104.7108.7180-167.763.8000109.5V186 W210 V215 E216 E218 V235L184-V186 HydrophobicContact CG-CG2 4.49Å; L184-W210 HydrophobicContact CD2-CE3 4.27Å; L184-W210 HydrophobicContact CD2-CH2 3.67Å; L184-W210 HydrophobicContact CD2-CZ2 4.46Å; L184-W210 HydrophobicContact CD2-CZ3 3.57Å; L184-V215 HydrophobicContact CB-CG1 3.87Å; L184-E216 PolarHBondContact N-O 3.11Å; L184-E218 PolarHBondContact O-N 3.2Å; L184-V235 HydrophobicContact CD1-CG2 3.64Å; L184-V235 HydrophobicContact CD2-CG2 3.89Å; L184-V235 HydrophobicContact CG-CG2 3.82Å
185K90.8Very high85.4Confident43 Ų4349.3 Ų49.319%0.18728%0.282CS..EExtended strand (participates in β ladder)trans-80.9120.2175.4-68.1176.5-177.1169.40109.5Y187 E218 K220 S234 V235K185-Y187 HydrophobicContact CB-CE2 3.83Å; K185-E218 CarbonylContact C-O 3.6Å; K185-E218 WeakPolarHBondContact CA-O 3.5Å; K185-K220 HydrophobicContact CB-CG 4.3Å; K185-S234 CarbonylContact O-C 3.57Å; K185-S234 WeakPolarHBondContact O-CA 3.28Å; K185-V235 PolarHBondContact O-N 2.87Å
186V93.4Very high85.9Confident0 Ų046.5 Ų46.50%028%0.275CS..EExtended strand (participates in β ladder)trans-108.4119.9-179.7-179.10000109.3L184 F188 W203 V217 E218 F219 K220 V235L184-V186 HydrophobicContact CG-CG2 4.49Å; V186-F188 HydrophobicContact CG1-CE1 3.88Å; V186-F188 HydrophobicContact CG1-CZ 4.26Å; V186-W203 HydrophobicContact CG1-CD2 4.47Å; V186-W203 HydrophobicContact CG1-CH2 4.43Å; V186-W203 HydrophobicContact CG1-CZ2 3.93Å; V186-W203 HydrophobicContact CG2-CE3 4.33Å; V186-W203 HydrophobicContact CG2-CH2 3.84Å; V186-W203 HydrophobicContact CG2-CZ2 4.18Å; V186-W203 HydrophobicContact CG2-CZ3 3.91Å; V186-V217 HydrophobicContact CB-CG1 4.46Å; V186-V217 HydrophobicContact CG2-CG1 3.62Å; V186-E218 PolarHBondContact N-O 3.04Å; V186-F219 HydrophobicContact CB-CD1 4.06Å; V186-F219 HydrophobicContact CB-CE1 4.45Å; V186-F219 HydrophobicContact CG1-CD1 4.31Å; V186-K220 PolarHBondContact O-N 3.01Å; V186-V235 CarbonylContact C-O 3.55Å; V186-V235 WeakPolarHBondContact CA-O 3.42Å; V186-V235 HydrophobicContact CG2-CB 4.24Å
187Y92.2Very high86.3Confident42 Ų4252.7 Ų52.717%0.16530%0.296CS..EExtended strand (participates in β ladder)trans-106.5154.1175.5-66.2-98.7000109.7K185 K220 H221 V223 F230 V235 V236 C237K185-Y187 HydrophobicContact CB-CE2 3.83Å; Y187-K220 HydrophobicContact CD1-CB 3.56Å; Y187-K220 HydrophobicContact CD1-CG 4.46Å; Y187-K220 HydrophobicContact CD2-CB 4.31Å; Y187-K220 HydrophobicContact CE1-CB 3.39Å; Y187-K220 HydrophobicContact CE1-CG 3.95Å; Y187-K220 HydrophobicContact CE2-CB 4.16Å; Y187-K220 HydrophobicContact CE2-CG 4.07Å; Y187-K220 HydrophobicContact CG-CB 4.03Å; Y187-H221 WeakPolarHBondContact CD1-O 3.45Å; Y187-V223 HydrophobicContact CD1-CG2 3.6Å; Y187-V223 HydrophobicContact CG-CG2 4.02Å; Y187-F230 HydrophobicContact CD1-CE1 4.03Å; Y187-F230 HydrophobicContact CD1-CZ 4.23Å; Y187-F230 HydrophobicContact CD2-CE1 4.16Å; Y187-F230 HydrophobicContact CD2-CE2 4.4Å; Y187-F230 AromaticContact CD2-CZ 3.97Å; Y187-F230 HydrophobicContact CD2-CZ 3.97Å; Y187-F230 HydrophobicContact CE1-CD1 4.46Å; Y187-F230 AromaticContact CE1-CE1 3.84Å; Y187-F230 HydrophobicContact CE1-CE1 3.84Å; Y187-F230 HydrophobicContact CE1-CZ 4.45Å; Y187-F230 HydrophobicContact CE2-CD1 4.21Å; Y187-F230 AromaticContact CE2-CE1 3.99Å; Y187-F230 HydrophobicContact CE2-CE1 3.99Å; Y187-F230 HydrophobicContact CE2-CZ 4.22Å; Y187-F230 HydrophobicContact CG-CE1 4.19Å; Y187-F230 AromaticContact CG-CZ 3.99Å; Y187-F230 HydrophobicContact CG-CZ 3.99Å; Y187-F230 AromaticContact CZ-CE1 3.82Å; Y187-V235 PolarHBondContact N-O 3.22Å; Y187-V236 CarbonylContact O-C 3.59Å; Y187-V236 WeakPolarHBondContact O-CA 3.43Å; Y187-C237 PolarHBondContact O-N 3.21Å
188F91.9Very high86.7Confident7 Ų755.8 Ų55.83%0.03131%0.313CS..EExtended strand (participates in β ladder)trans-112.4143179.7-53-63.4000112.1V186 S190 A196 V199 M200 F219 D222 V223 C237V186-F188 HydrophobicContact CG1-CE1 3.88Å; V186-F188 HydrophobicContact CG1-CZ 4.26Å; F188-S190 PolarHBondContact O-N 3.4Å; F188-A196 HydrophobicContact CD2-CB 4.46Å; F188-V199 HydrophobicContact CD1-CB 4.38Å; F188-V199 HydrophobicContact CD1-CG1 3.55Å; F188-V199 HydrophobicContact CE1-CB 4.44Å; F188-V199 HydrophobicContact CE1-CG1 3.58Å; F188-M200 HydrophobicContact CE1-CG 4.21Å; F188-M200 HydrophobicContact CE2-CG 3.49Å; F188-M200 VanDerWaalsContact CE2-CG 3.49Å; F188-M200 HydrophobicContact CE2-SD 3.94Å; F188-M200 HydrophobicContact CZ-CB 4.47Å; F188-M200 HydrophobicContact CZ-CG 3.29Å; F188-M200 HydrophobicContact CZ-SD 4.34Å; F188-F219 HydrophobicContact CE1-CD1 4.41Å; F188-F219 HydrophobicContact CE2-CB 4.25Å; F188-F219 HydrophobicContact CE2-CD1 4.18Å; F188-F219 HydrophobicContact CZ-CB 4.39Å; F188-F219 AromaticContact CZ-CD1 3.49Å; F188-F219 HydrophobicContact CZ-CD1 3.49Å; F188-F219 VanDerWaalsContact CZ-CD1 3.49Å; F188-F219 HydrophobicContact CZ-CE1 4.08Å; F188-F219 HydrophobicContact CZ-CG 4.2Å; F188-D222 CarbonylContact O-C 3.58Å; F188-D222 WeakPolarHBondContact O-CA 3.39Å; F188-V223 PolarHBondContact O-N 3.08Å; F188-C237 CarbonylContact C-O 3.59Å; F188-C237 VanDerWaalsContact CA-O 3.29Å; F188-C237 WeakPolarHBondContact CA-O 3.4Å
189F90.1Very high87.3Confident6 Ų653.7 Ų53.73%0.02630%0.298CS..BIsolated β-bridgetrans-69.4121169.8-78.2-71.3000110.3N191 S192 W226 F228 V236 C237 L240 I262F189-N191 PolarHBondContact O-N 3.39Å; F189-S192 WeakPolarHBondContact O-CB 3.34Å; F189-S192 PolarHBondContact O-N 2.89Å; F189-S192 VanDerWaalsContact O-N 3.1Å; F189-W226 HydrophobicContact CD1-CH2 4.4Å; F189-W226 HydrophobicContact CD1-CZ3 4.4Å; F189-W226 HydrophobicContact CE1-CD2 4.04Å; F189-W226 AromaticContact CE1-CE3 3.54Å; F189-W226 HydrophobicContact CE1-CE3 3.54Å; F189-W226 AromaticContact CE1-CH2 3.83Å; F189-W226 HydrophobicContact CE1-CH2 3.83Å; F189-W226 HydrophobicContact CE1-CZ2 4.28Å; F189-W226 AromaticContact CE1-CZ3 3.42Å; F189-W226 HydrophobicContact CE1-CZ3 3.42Å; F189-W226 VanDerWaalsContact CE1-CZ3 3.42Å; F189-W226 HydrophobicContact CE2-CZ3 4.26Å; F189-W226 AromaticContact CZ-CE3 3.75Å; F189-W226 HydrophobicContact CZ-CE3 3.75Å; F189-W226 AromaticContact CZ-CH2 3.97Å; F189-W226 HydrophobicContact CZ-CH2 3.97Å; F189-W226 AromaticContact CZ-CZ3 3.34Å; F189-W226 HydrophobicContact CZ-CZ3 3.34Å; F189-F228 HydrophobicContact CE1-CE1 4.44Å; F189-F228 AromaticContact CE1-CZ 3.8Å; F189-F228 HydrophobicContact CE1-CZ 3.8Å; F189-F228 AromaticContact CZ-CZ 3.93Å; F189-F228 HydrophobicContact CZ-CZ 3.93Å; F189-V236 HydrophobicContact CD1-CG1 4.17Å; F189-V236 HydrophobicContact CD2-CG1 3.94Å; F189-V236 HydrophobicContact CE1-CG1 3.88Å; F189-V236 HydrophobicContact CE2-CB 4.32Å; F189-V236 HydrophobicContact CE2-CG1 3.6Å; F189-V236 HydrophobicContact CG-CG1 4.2Å; F189-V236 HydrophobicContact CZ-CB 4.31Å; F189-V236 HydrophobicContact CZ-CG1 3.57Å; F189-C237 PolarHBondContact N-O 3.44Å; F189-L240 HydrophobicContact CD2-CD1 4.43Å; F189-I262 HydrophobicContact CD2-CG2 4.03Å; F189-I262 HydrophobicContact CE2-CG2 3.44Å; F189-I262 VanDerWaalsContact CE2-CG2 3.44Å; F189-I262 HydrophobicContact CZ-CG2 4.15Å
190S85.9Confident88Confident65 Ų6554.7 Ų54.746%0.45530%0.303SS..THydrogen-bonded Turntrans-62-24.6176.558.50000114.1F188 S192 V223 P224F188-S190 PolarHBondContact O-N 3.4Å; S190-S192 VanDerWaalsContact C-N 3.33Å; S190-V223 PolarHBondContact N-O 2.65Å; S190-V223 PolarHBondContact OG-O 2.9Å; S190-V223 VanDerWaalsContact OG-O 3.1Å; S190-P224 VanDerWaalsContact OG-CA 3.32Å; S190-P224 WeakPolarHBondContact OG-CA 3.29Å
191N87.4Confident89.2Confident69 Ų6953 Ų5337%0.36929%0.29SS..THydrogen-bonded Turntrans-94.418177.167.2-16.8000113.3F189 L240F189-N191 PolarHBondContact O-N 3.39Å; N191-L240 WeakPolarHBondContact O-CD2 3.4Å
192S88.3Confident90.2Very high24 Ų2449 Ų4917%0.16827%0.269CS..  trans-61136.3173.4174.80000110.7F189 S190 S194 V239F189-S192 WeakPolarHBondContact O-CB 3.34Å; F189-S192 PolarHBondContact O-N 2.89Å; F189-S192 VanDerWaalsContact O-N 3.1Å; S190-S192 VanDerWaalsContact C-N 3.33Å; S192-S194 VanDerWaalsContact C-N 3.26Å; S192-S194 WeakPolarHBondContact CB-O 3.49Å; S192-S194 PolarHBondContact O-N 3.34Å; S192-S194 PolarHBondContact OG-N 3.01Å; S192-S194 PolarHBondContact OG-O 3.34Å; S192-V239 CarbonylContact C-O 3.49Å; S192-V239 VanDerWaalsContact CA-O 3.23Å; S192-V239 WeakPolarHBondContact CA-O 3.44Å; S192-V239 PolarHBondContact OG-N 2.82Å; S192-V239 VanDerWaalsContact OG-N 3.11Å; S192-V239 PolarHBondContact OG-O 3.39Å
193T90.8Very high90.9Very high90 Ų9045.4 Ų45.455%0.55225%0.245SC*.SBendtrans-68.6-28175.554.50000112.2V239 A241T193-V239 PolarHBondContact N-O 2.99Å; T193-V239 VanDerWaalsContact OG1-CG1 3.26Å; T193-V239 WeakPolarHBondContact OG1-CG1 3.39Å; T193-V239 PolarHBondContact OG1-O 3.44Å; T193-A241 HydrophobicContact CG2-CB 4.33Å
194S90.3Very high91.4Very high25 Ų2545 Ų4518%0.17525%0.245CC..SBendtrans-95.8148.9173.7-600000110.5S192S192-S194 VanDerWaalsContact C-N 3.26Å; S192-S194 WeakPolarHBondContact CB-O 3.49Å; S192-S194 PolarHBondContact O-N 3.34Å; S192-S194 PolarHBondContact OG-N 3.01Å; S192-S194 PolarHBondContact OG-O 3.34Å
195S90.1Very high91.6Very high55 Ų5547.7 Ų47.739%0.38526%0.262SS..  trans-64.6150.6179.681.20000111.1K197 D198 V199S195-K197 PolarHBondContact O-N 3.13Å; S195-K197 VanDerWaalsContact O-N 3.14Å; S195-D198 WeakPolarHBondContact CB-OD2 3.32Å; S195-D198 PolarHBondContact N-OD2 3.17Å; S195-D198 PolarHBondContact O-N 3.31Å; S195-D198 PolarHBondContact OG-N 2.91Å; S195-D198 PolarHBondContact OG-OD2 3.22Å; S195-V199 PolarHBondContact O-N 2.81Å; S195-V199 VanDerWaalsContact O-N 3.14Å
196A88.4Confident91.8Very high35 Ų3546.1 Ų46.129%0.28926%0.255SS..Hα-helixtrans-55.9-31.9175.300000111.9F188 V199 M200F188-A196 HydrophobicContact CD2-CB 4.46Å; A196-V199 PolarHBondContact O-N 3.19Å; A196-M200 VanDerWaalsContact O-CB 3.3Å; A196-M200 WeakPolarHBondContact O-CB 3.4Å; A196-M200 WeakPolarHBondContact O-CG 3.3Å; A196-M200 PolarHBondContact O-N 2.87Å
197K90.7Very high91.8Very high159 Ų15948.2 Ų48.269%0.69127%0.27SS*.Hα-helixtrans-63.1-44.6175.7-65-179.7-179.5177.70112S195 M200 N201S195-K197 PolarHBondContact O-N 3.13Å; S195-K197 VanDerWaalsContact O-N 3.14Å; K197-M200 PolarHBondContact O-N 2.91Å; K197-N201 WeakPolarHBondContact O-CB 3.39Å; K197-N201 PolarHBondContact O-N 2.81Å; K197-N201 PolarHBondContact O-ND2 3.38Å; K197-N201 PolarHBondContact O-OD1 3.33Å
198D93.1Very high91.7Very high67 Ų6748 Ų4836%0.35828%0.28SS..Hα-helixtrans-67.1-42.1-179.7-55.6-43.6000111.1S195 N201 V202 L266S195-D198 WeakPolarHBondContact CB-OD2 3.32Å; S195-D198 PolarHBondContact N-OD2 3.17Å; S195-D198 PolarHBondContact O-N 3.31Å; S195-D198 PolarHBondContact OG-N 2.91Å; S195-D198 PolarHBondContact OG-OD2 3.22Å; D198-N201 WeakPolarHBondContact O-CB 3.38Å; D198-N201 PolarHBondContact O-N 3.33Å; D198-V202 PolarHBondContact O-N 2.91Å; D198-L266 HydrophobicContact CB-CD1 3.97Å; D198-L266 HydrophobicContact CB-CD2 4.02Å
199V93.4Very high91.7Very high1 Ų149 Ų491%0.00629%0.286CS..Hα-helixtrans-60.4-48.2174.3176.90000110.1F188 S195 A196 N201 V202 W203 V239 L266 L269F188-V199 HydrophobicContact CD1-CB 4.38Å; F188-V199 HydrophobicContact CD1-CG1 3.55Å; F188-V199 HydrophobicContact CE1-CB 4.44Å; F188-V199 HydrophobicContact CE1-CG1 3.58Å; S195-V199 PolarHBondContact O-N 2.81Å; S195-V199 VanDerWaalsContact O-N 3.14Å; A196-V199 PolarHBondContact O-N 3.19Å; V199-N201 VanDerWaalsContact C-N 3.31Å; V199-N201 PolarHBondContact O-N 2.95Å; V199-V202 PolarHBondContact O-N 3.49Å; V199-W203 VanDerWaalsContact O-CD1 3.31Å; V199-W203 PolarHBondContact O-N 3.29Å; V199-V239 HydrophobicContact CG2-CG2 4.24Å; V199-L266 HydrophobicContact CG2-CD2 4.38Å; V199-L269 HydrophobicContact CB-CD2 4.25Å; V199-L269 HydrophobicContact CG1-CD2 3.74Å; V199-L269 HydrophobicContact CG2-CD2 4.29Å
200M93.2Very high91.8Very high53 Ų5348.9 Ų48.926%0.26129%0.285SS..Hα-helixtrans-58.3-40.3175.7-76.317573.400112.5F188 A196 K197 V202 W203 Q204 F219F188-M200 HydrophobicContact CE1-CG 4.21Å; F188-M200 HydrophobicContact CE2-CG 3.49Å; F188-M200 VanDerWaalsContact CE2-CG 3.49Å; F188-M200 HydrophobicContact CE2-SD 3.94Å; F188-M200 HydrophobicContact CZ-CB 4.47Å; F188-M200 HydrophobicContact CZ-CG 3.29Å; F188-M200 HydrophobicContact CZ-SD 4.34Å; A196-M200 VanDerWaalsContact O-CB 3.3Å; A196-M200 WeakPolarHBondContact O-CB 3.4Å; A196-M200 WeakPolarHBondContact O-CG 3.3Å; A196-M200 PolarHBondContact O-N 2.87Å; K197-M200 PolarHBondContact O-N 2.91Å; M200-V202 VanDerWaalsContact C-N 3.33Å; M200-V202 PolarHBondContact O-N 2.95Å; M200-W203 PolarHBondContact O-N 3.4Å; M200-Q204 WeakPolarHBondContact O-CG 3.34Å; M200-Q204 PolarHBondContact O-N 3.36Å; M200-F219 HydrophobicContact CE-CB 4.29Å; M200-F219 HydrophobicContact CE-CD2 3.94Å; M200-F219 HydrophobicContact CE-CG 4.15Å
201N94.6Very high92Very high82 Ų8253 Ų5344%0.43930%0.295SS..Hα-helixtrans-60.5-42.5179-70.5-18.5000111.4K197 D198 V199 W203 Q204 V205K197-N201 WeakPolarHBondContact O-CB 3.39Å; K197-N201 PolarHBondContact O-N 2.81Å; K197-N201 PolarHBondContact O-ND2 3.38Å; K197-N201 PolarHBondContact O-OD1 3.33Å; D198-N201 WeakPolarHBondContact O-CB 3.38Å; D198-N201 PolarHBondContact O-N 3.33Å; V199-N201 VanDerWaalsContact C-N 3.31Å; V199-N201 PolarHBondContact O-N 2.95Å; N201-W203 VanDerWaalsContact C-N 3.34Å; N201-W203 PolarHBondContact O-N 3.5Å; N201-Q204 PolarHBondContact O-N 3.38Å; N201-V205 WeakPolarHBondContact O-CG2 3.38Å; N201-V205 PolarHBondContact O-N 3.05Å
202V95.4Very high91.9Very high16 Ų1654.4 Ų54.410%0.09730%0.301CS..Hα-helixtrans-59.9-45176.1-178.30000110.9D198 V199 M200 Q204 V205 L206 L266 L269 I273D198-V202 PolarHBondContact O-N 2.91Å; V199-V202 PolarHBondContact O-N 3.49Å; M200-V202 VanDerWaalsContact C-N 3.33Å; M200-V202 PolarHBondContact O-N 2.95Å; V202-Q204 VanDerWaalsContact C-N 3.34Å; V202-Q204 PolarHBondContact O-N 3.22Å; V202-V205 PolarHBondContact O-N 2.92Å; V202-L206 HydrophobicContact CG1-CD1 4.32Å; V202-L206 WeakPolarHBondContact O-CG 3.36Å; V202-L206 PolarHBondContact O-N 3.49Å; V202-L266 HydrophobicContact CG2-CB 4.34Å; V202-L266 HydrophobicContact CG2-CD2 4.19Å; V202-L269 HydrophobicContact CB-CD2 4.24Å; V202-L269 HydrophobicContact CG1-CD2 4.43Å; V202-L269 HydrophobicContact CG1-CG 4.5Å; V202-L269 HydrophobicContact CG2-CD2 4.39Å; V202-I273 HydrophobicContact CG1-CD1 3.85Å
203W95.4Very high91.7Very high4 Ų454.1 Ų54.12%0.01530%0.298CS..Hα-helixtrans-62.7-38.7175.7-79.891.1000113V186 V199 M200 N201 L206 S207 W210 V217 F219 V235 C237 L261 I273 L276V186-W203 HydrophobicContact CG1-CD2 4.47Å; V186-W203 HydrophobicContact CG1-CH2 4.43Å; V186-W203 HydrophobicContact CG1-CZ2 3.93Å; V186-W203 HydrophobicContact CG2-CE3 4.33Å; V186-W203 HydrophobicContact CG2-CH2 3.84Å; V186-W203 HydrophobicContact CG2-CZ2 4.18Å; V186-W203 HydrophobicContact CG2-CZ3 3.91Å; V199-W203 VanDerWaalsContact O-CD1 3.31Å; V199-W203 PolarHBondContact O-N 3.29Å; M200-W203 PolarHBondContact O-N 3.4Å; N201-W203 VanDerWaalsContact C-N 3.34Å; N201-W203 PolarHBondContact O-N 3.5Å; W203-L206 CarbonylContact O-C 3.58Å; W203-L206 PolarHBondContact O-N 3.37Å; W203-S207 PolarHBondContact O-N 3.11Å; W203-W210 HydrophobicContact CE3-CZ2 4.32Å; W203-W210 AromaticContact CE3-NE1 3.84Å; W203-W210 AromaticContact CH2-CZ2 3.92Å; W203-W210 HydrophobicContact CH2-CZ2 3.92Å; W203-W210 AromaticContact CZ3-CE2 3.64Å; W203-W210 HydrophobicContact CZ3-CH2 4.22Å; W203-W210 AromaticContact CZ3-CZ2 3.39Å; W203-W210 HydrophobicContact CZ3-CZ2 3.39Å; W203-W210 AromaticContact CZ3-NE1 3.76Å; W203-V217 HydrophobicContact CE3-CG1 4.06Å; W203-V217 HydrophobicContact CZ3-CG1 4.28Å; W203-F219 HydrophobicContact CB-CE1 3.66Å; W203-F219 HydrophobicContact CB-CZ 3.62Å; W203-F219 HydrophobicContact CD2-CE1 4.37Å; W203-F219 AromaticContact CG-CE1 3.92Å; W203-F219 HydrophobicContact CG-CE1 3.92Å; W203-F219 HydrophobicContact CG-CZ 4.37Å; W203-V235 HydrophobicContact CH2-CG1 4.23Å; W203-V235 HydrophobicContact CZ2-CG1 4.15Å; W203-C237 HydrophobicContact CZ2-CB 4.45Å; W203-C237 PolarHBondContact NE1-SG 3.33Å; W203-L261 HydrophobicContact CZ2-CD2 4.36Å; W203-I273 HydrophobicContact CD2-CD1 3.81Å; W203-I273 HydrophobicContact CD2-CG1 4.27Å; W203-I273 HydrophobicContact CE3-CD1 4.49Å; W203-I273 HydrophobicContact CG-CD1 3.88Å; W203-I273 HydrophobicContact CH2-CG1 4.42Å; W203-I273 HydrophobicContact CZ2-CD1 4.32Å; W203-I273 HydrophobicContact CZ2-CG1 4.01Å; W203-L276 HydrophobicContact CH2-CD2 4.18Å
204Q94.5Very high91.5Very high97 Ų9758.3 Ų58.345%0.45331%0.308SS..Hα-helixtrans-68.2-42179.5-74.4177.45.700112.3M200 N201 V202 L206 S207 F219M200-Q204 WeakPolarHBondContact O-CG 3.34Å; M200-Q204 PolarHBondContact O-N 3.36Å; N201-Q204 PolarHBondContact O-N 3.38Å; V202-Q204 VanDerWaalsContact C-N 3.34Å; V202-Q204 PolarHBondContact O-N 3.22Å; Q204-L206 VanDerWaalsContact C-N 3.27Å; Q204-L206 PolarHBondContact O-N 3.12Å; Q204-S207 WeakPolarHBondContact O-CB 3.48Å; Q204-S207 PolarHBondContact O-N 2.99Å; Q204-S207 VanDerWaalsContact O-N 3.12Å; Q204-S207 PolarHBondContact O-OG 2.71Å; Q204-F219 HydrophobicContact CG-CE2 4.25Å; Q204-F219 HydrophobicContact CG-CZ 4.43Å
205V94.6Very high91.4Very high62 Ų6257.6 Ų57.638%0.37630%0.303SS..Hα-helixtrans-59.1-42.6174.5173.60000110.5N201 V202 S207 S371 L372N201-V205 WeakPolarHBondContact O-CG2 3.38Å; N201-V205 PolarHBondContact O-N 3.05Å; V202-V205 PolarHBondContact O-N 2.92Å; V205-S207 VanDerWaalsContact C-N 3.26Å; V205-S207 PolarHBondContact O-N 3.21Å; V205-S371 WeakPolarHBondContact CG1-O 3.36Å; V205-L372 HydrophobicContact CG1-CD2 3.96Å
206L94.8Very high91.3Very high10 Ų1059.9 Ų59.95%0.05231%0.307CS..THydrogen-bonded Turntrans-83.67.3179.4-58.8179.6000113.9V202 W203 Q204 G208 L209 I273 L372V202-L206 HydrophobicContact CG1-CD1 4.32Å; V202-L206 WeakPolarHBondContact O-CG 3.36Å; V202-L206 PolarHBondContact O-N 3.49Å; W203-L206 CarbonylContact O-C 3.58Å; W203-L206 PolarHBondContact O-N 3.37Å; Q204-L206 VanDerWaalsContact C-N 3.27Å; Q204-L206 PolarHBondContact O-N 3.12Å; L206-G208 PolarHBondContact O-N 2.85Å; L206-G208 VanDerWaalsContact O-N 3.14Å; L206-L209 HydrophobicContact CB-CD1 4.38Å; L206-L209 HydrophobicContact CD2-CD1 4.29Å; L206-L209 WeakPolarHBondContact O-CB 3.44Å; L206-L209 PolarHBondContact O-N 3.41Å; L206-L209 VanDerWaalsContact O-N 3.08Å; L206-I273 HydrophobicContact CB-CG2 4.19Å; L206-I273 HydrophobicContact CD1-CB 3.83Å; L206-I273 HydrophobicContact CD1-CD1 4.2Å; L206-I273 HydrophobicContact CD1-CG2 3.63Å; L206-L372 HydrophobicContact CD2-CD2 4.37Å
207S93.4Very high91.5Very high44 Ų4460 Ų6031%0.30830%0.304SS..Hα-helixtrans-60.2-26.8-178.1650000113.7W203 Q204 V205 L209 W210 K211W203-S207 PolarHBondContact O-N 3.11Å; Q204-S207 WeakPolarHBondContact O-CB 3.48Å; Q204-S207 PolarHBondContact O-N 2.99Å; Q204-S207 VanDerWaalsContact O-N 3.12Å; Q204-S207 PolarHBondContact O-OG 2.71Å; V205-S207 VanDerWaalsContact C-N 3.26Å; V205-S207 PolarHBondContact O-N 3.21Å; S207-L209 VanDerWaalsContact C-N 3.27Å; S207-L209 PolarHBondContact O-N 2.74Å; S207-W210 PolarHBondContact O-N 2.84Å; S207-K211 WeakPolarHBondContact O-CG 3.43Å; S207-K211 PolarHBondContact O-N 3.34Å; S207-K211 VanDerWaalsContact O-N 3.1Å
208G90.4Very high91.5Very high36 Ų3656 Ų5637%0.37129%0.288SS..Hα-helixtrans-58.7-37.3175.200000113L206 W210 K211 I212L206-G208 PolarHBondContact O-N 2.85Å; L206-G208 VanDerWaalsContact O-N 3.14Å; G208-W210 PolarHBondContact O-N 2.93Å; G208-K211 PolarHBondContact O-N 2.96Å; G208-I212 WeakPolarHBondContact O-CG1 2.99Å; G208-I212 PolarHBondContact O-N 2.99Å
209L91.4Very high91.4Very high29 Ų2955.8 Ų55.815%0.15228%0.284CS..Hα-helixtrans-63.9-42.8179.1-60.9-179.7000111.3L206 S207 I212 L213 V277L206-L209 HydrophobicContact CB-CD1 4.38Å; L206-L209 HydrophobicContact CD2-CD1 4.29Å; L206-L209 WeakPolarHBondContact O-CB 3.44Å; L206-L209 PolarHBondContact O-N 3.41Å; L206-L209 VanDerWaalsContact O-N 3.08Å; S207-L209 VanDerWaalsContact C-N 3.27Å; S207-L209 PolarHBondContact O-N 2.74Å; L209-I212 PolarHBondContact O-N 3.45Å; L209-L213 PolarHBondContact O-N 3.44Å; L209-V277 HydrophobicContact CB-CG1 4.05Å; L209-V277 HydrophobicContact CB-CG2 4.07Å; L209-V277 HydrophobicContact CD1-CG2 4.35Å
210W91.5Very high91.1Very high4 Ų458.7 Ų58.72%0.01530%0.297CS..Hα-helixtrans-70.1-36.1179.2-60.399.9000113L184 W203 S207 G208 I212 L213 K214 V215 V217 I273 L276 V277 V280L184-W210 HydrophobicContact CD2-CE3 4.27Å; L184-W210 HydrophobicContact CD2-CH2 3.67Å; L184-W210 HydrophobicContact CD2-CZ2 4.46Å; L184-W210 HydrophobicContact CD2-CZ3 3.57Å; W203-W210 HydrophobicContact CE3-CZ2 4.32Å; W203-W210 AromaticContact CE3-NE1 3.84Å; W203-W210 AromaticContact CH2-CZ2 3.92Å; W203-W210 HydrophobicContact CH2-CZ2 3.92Å; W203-W210 AromaticContact CZ3-CE2 3.64Å; W203-W210 HydrophobicContact CZ3-CH2 4.22Å; W203-W210 AromaticContact CZ3-CZ2 3.39Å; W203-W210 HydrophobicContact CZ3-CZ2 3.39Å; W203-W210 AromaticContact CZ3-NE1 3.76Å; S207-W210 PolarHBondContact O-N 2.84Å; G208-W210 PolarHBondContact O-N 2.93Å; W210-I212 VanDerWaalsContact C-N 3.33Å; W210-I212 PolarHBondContact O-N 2.81Å; W210-L213 CarbonylContact O-C 3.54Å; W210-L213 WeakPolarHBondContact O-CB 3.47Å; W210-L213 PolarHBondContact O-N 3.25Å; W210-L213 VanDerWaalsContact O-N 3.13Å; W210-K214 PolarHBondContact O-N 3.33Å; W210-K214 VanDerWaalsContact O-N 3.17Å; W210-V215 HydrophobicContact CE3-CB 4.25Å; W210-V215 HydrophobicContact CE3-CG1 4.13Å; W210-V215 PolarHBondContact O-N 3.21Å; W210-V217 HydrophobicContact CB-CG2 3.93Å; W210-V217 HydrophobicContact CD2-CG2 3.83Å; W210-V217 HydrophobicContact CE3-CG2 4.25Å; W210-V217 HydrophobicContact CG-CG2 3.67Å; W210-I273 HydrophobicContact CZ2-CG2 4.12Å; W210-L276 HydrophobicContact CH2-CD2 3.85Å; W210-L276 HydrophobicContact CH2-CG 3.91Å; W210-L276 HydrophobicContact CZ2-CD2 4.24Å; W210-V277 HydrophobicContact CD2-CG2 4.01Å; W210-V277 HydrophobicContact CE3-CG2 4.37Å; W210-V277 HydrophobicContact CH2-CG2 3.95Å; W210-V277 HydrophobicContact CZ2-CG2 3.53Å; W210-V277 HydrophobicContact CZ3-CG2 4.34Å; W210-V280 HydrophobicContact CZ3-CG2 4.46Å
211K89.6Confident90.3Very high151 Ų15164.4 Ų64.466%0.65732%0.322SS*.Hα-helixtrans-61.8-39.8174.6-72.8174-176.6173.60112.1S207 G208 L213 K214S207-K211 WeakPolarHBondContact O-CG 3.43Å; S207-K211 PolarHBondContact O-N 3.34Å; S207-K211 VanDerWaalsContact O-N 3.1Å; G208-K211 PolarHBondContact O-N 2.96Å; K211-L213 PolarHBondContact O-N 2.95Å; K211-K214 PolarHBondContact O-N 3.32Å
212I85.1Confident89.5Confident99 Ų9964.7 Ų64.751%0.50832%0.324SS..Hα-helixtrans-60.2-38.4175.3-67.6165.2000110.5G208 L209 W210 K214G208-I212 WeakPolarHBondContact O-CG1 2.99Å; G208-I212 PolarHBondContact O-N 2.99Å; L209-I212 PolarHBondContact O-N 3.45Å; W210-I212 VanDerWaalsContact C-N 3.33Å; W210-I212 PolarHBondContact O-N 2.81Å; I212-K214 PolarHBondContact O-N 2.96Å
213L85.1Confident88.7Confident17 Ų1764.8 Ų64.89%0.08933%0.325CS..THydrogen-bonded Turntrans-77-3.3176.1-58.1-171.5000114.2L209 W210 K211 V215 V277 V280 R281 L285L209-L213 PolarHBondContact O-N 3.44Å; W210-L213 CarbonylContact O-C 3.54Å; W210-L213 WeakPolarHBondContact O-CB 3.47Å; W210-L213 PolarHBondContact O-N 3.25Å; W210-L213 VanDerWaalsContact O-N 3.13Å; K211-L213 PolarHBondContact O-N 2.95Å; L213-V215 HydrophobicContact CB-CG2 4.02Å; L213-V215 PolarHBondContact O-N 3.47Å; L213-V277 HydrophobicContact CD1-CG1 3.96Å; L213-V280 HydrophobicContact CD1-CB 4.43Å; L213-V280 HydrophobicContact CD1-CG1 4.04Å; L213-R281 HydrophobicContact CD1-CB 4.32Å; L213-R281 HydrophobicContact CD2-CB 3.79Å; L213-R281 HydrophobicContact CD2-CG 3.83Å; L213-L285 HydrophobicContact CB-CD1 3.71Å; L213-L285 HydrophobicContact CD1-CD1 4.34Å; L213-L285 HydrophobicContact CD2-CD1 3.9Å; L213-L285 HydrophobicContact CG-CD1 4.17Å
214K85.7Confident87.4Confident179 Ų17969.3 Ų69.378%0.77835%0.354SS*.THydrogen-bonded Turntrans55.631.3-171.9-54.6179-179.1175.60113.4W210 K211 I212W210-K214 PolarHBondContact O-N 3.33Å; W210-K214 VanDerWaalsContact O-N 3.17Å; K211-K214 PolarHBondContact O-N 3.32Å; I212-K214 PolarHBondContact O-N 2.96Å
215V88.5Confident86Confident9 Ų968 Ų686%0.05536%0.355CS..PPolyproline II helixtrans-101.4123.8175.7177.70000109.1M179 P182 L184 W210 L213M179-V215 HydrophobicContact CE-CG2 4Å; P182-V215 WeakPolarHBondContact O-CA 3.26Å; L184-V215 HydrophobicContact CB-CG1 3.87Å; W210-V215 HydrophobicContact CE3-CB 4.25Å; W210-V215 HydrophobicContact CE3-CG1 4.13Å; W210-V215 PolarHBondContact O-N 3.21Å; L213-V215 HydrophobicContact CB-CG2 4.02Å; L213-V215 PolarHBondContact O-N 3.47Å
216E89.3Confident84.6Confident104 Ų10469.7 Ų69.749%0.48636%0.355SS..EExtended strand (participates in β ladder)trans-84.7121.9174.6-172.4-177.7-178.300109.7P182 K183 L184P182-E216 PolarHBondContact O-N 3.44Å; K183-E216 CarbonylContact C-O 3.54Å; K183-E216 WeakPolarHBondContact CA-O 3.47Å; K183-E216 WeakPolarHBondContact CE-OE2 3.19Å; K183-E216 HydrophobicContact CG-CB 4.3Å; K183-E216 IonicContact NZ-OE1 2.63Å; K183-E216 IonicContact NZ-OE2 3.57Å; K183-E216 PolarHBondContact NZ-OE2 3.48Å; L184-E216 PolarHBondContact N-O 3.11Å
217V91.8Very high83.5Confident37 Ų3778.1 Ų78.122%0.22439%0.391CS..EExtended strand (participates in β ladder)trans-95.6120177.3178.90000109.1V186 W203 W210 F219V186-V217 HydrophobicContact CB-CG1 4.46Å; V186-V217 HydrophobicContact CG2-CG1 3.62Å; W203-V217 HydrophobicContact CE3-CG1 4.06Å; W203-V217 HydrophobicContact CZ3-CG1 4.28Å; W210-V217 HydrophobicContact CB-CG2 3.93Å; W210-V217 HydrophobicContact CD2-CG2 3.83Å; W210-V217 HydrophobicContact CE3-CG2 4.25Å; W210-V217 HydrophobicContact CG-CG2 3.67Å; V217-F219 HydrophobicContact CG1-CD1 4.46Å; V217-F219 HydrophobicContact CG1-CE1 3.94Å; V217-F219 HydrophobicContact CG1-CZ 4.15Å
218E90.4Very high82.7Confident75 Ų7577.6 Ų77.635%0.3538%0.384SS..EExtended strand (participates in β ladder)trans-114.1119.7178.7-168.9-172.9-172.900110.5L184 K185 V186 K220L184-E218 PolarHBondContact O-N 3.2Å; K185-E218 CarbonylContact C-O 3.6Å; K185-E218 WeakPolarHBondContact CA-O 3.5Å; V186-E218 PolarHBondContact N-O 3.04Å; E218-K220 WeakPolarHBondContact OE1-CE 3.39Å; E218-K220 IonicContact OE1-NZ 2.87Å; E218-K220 PolarHBondContact OE1-NZ 3.07Å; E218-K220 WeakPolarHBondContact OE2-CE 3.27Å; E218-K220 IonicContact OE2-NZ 2.59Å; E218-K220 PolarHBondContact OE2-NZ 3.48Å
219F91.2Very high82Confident62 Ų6283.3 Ų83.327%0.27241%0.405SS..EExtended strand (participates in β ladder)trans-80.7136.3177.7-56.6-62.8000111.5V186 F188 M200 W203 Q204 V217V186-F219 HydrophobicContact CB-CD1 4.06Å; V186-F219 HydrophobicContact CB-CE1 4.45Å; V186-F219 HydrophobicContact CG1-CD1 4.31Å; F188-F219 HydrophobicContact CE1-CD1 4.41Å; F188-F219 HydrophobicContact CE2-CB 4.25Å; F188-F219 HydrophobicContact CE2-CD1 4.18Å; F188-F219 HydrophobicContact CZ-CB 4.39Å; F188-F219 AromaticContact CZ-CD1 3.49Å; F188-F219 HydrophobicContact CZ-CD1 3.49Å; F188-F219 VanDerWaalsContact CZ-CD1 3.49Å; F188-F219 HydrophobicContact CZ-CE1 4.08Å; F188-F219 HydrophobicContact CZ-CG 4.2Å; M200-F219 HydrophobicContact CE-CB 4.29Å; M200-F219 HydrophobicContact CE-CD2 3.94Å; M200-F219 HydrophobicContact CE-CG 4.15Å; W203-F219 HydrophobicContact CB-CE1 3.66Å; W203-F219 HydrophobicContact CB-CZ 3.62Å; W203-F219 HydrophobicContact CD2-CE1 4.37Å; W203-F219 AromaticContact CG-CE1 3.92Å; W203-F219 HydrophobicContact CG-CE1 3.92Å; W203-F219 HydrophobicContact CG-CZ 4.37Å; Q204-F219 HydrophobicContact CG-CE2 4.25Å; Q204-F219 HydrophobicContact CG-CZ 4.43Å; V217-F219 HydrophobicContact CG1-CD1 4.46Å; V217-F219 HydrophobicContact CG1-CE1 3.94Å; V217-F219 HydrophobicContact CG1-CZ 4.15Å
220K86.5Confident81.5Confident63 Ų6383 Ų8327%0.27440%0.403SS..  trans-122.2170.9179.3-62.6-61.6-174.3-172.50111.2K185 V186 Y187 E218K185-K220 HydrophobicContact CB-CG 4.3Å; V186-K220 PolarHBondContact O-N 3.01Å; Y187-K220 HydrophobicContact CD1-CB 3.56Å; Y187-K220 HydrophobicContact CD1-CG 4.46Å; Y187-K220 HydrophobicContact CD2-CB 4.31Å; Y187-K220 HydrophobicContact CE1-CB 3.39Å; Y187-K220 HydrophobicContact CE1-CG 3.95Å; Y187-K220 HydrophobicContact CE2-CB 4.16Å; Y187-K220 HydrophobicContact CE2-CG 4.07Å; Y187-K220 HydrophobicContact CG-CB 4.03Å; E218-K220 WeakPolarHBondContact OE1-CE 3.39Å; E218-K220 IonicContact OE1-NZ 2.87Å; E218-K220 PolarHBondContact OE1-NZ 3.07Å; E218-K220 WeakPolarHBondContact OE2-CE 3.27Å; E218-K220 IonicContact OE2-NZ 2.59Å; E218-K220 PolarHBondContact OE2-NZ 3.48Å
221H77.3Confident80.8Confident173 Ų17386.9 Ų86.980%0.80144%0.436SS*.  trans-63160.6-179.7-64-59.6000113.3Y187Y187-H221 WeakPolarHBondContact CD1-O 3.45Å
222D78.3Confident80.4Confident87 Ų8784 Ų8447%0.46543%0.425SS..  trans-65144.8-179.7-56.1-23.5000112F188F188-D222 CarbonylContact O-C 3.58Å; F188-D222 WeakPolarHBondContact O-CA 3.39Å
223V78.7Confident80.3Confident19 Ų1981.3 Ų81.312%0.11541%0.414CS..BIsolated β-bridgetrans-108128.7178-174.80000109.1Y187 F188 S190 C225 F228 F230Y187-V223 HydrophobicContact CD1-CG2 3.6Å; Y187-V223 HydrophobicContact CG-CG2 4.02Å; F188-V223 PolarHBondContact O-N 3.08Å; S190-V223 PolarHBondContact N-O 2.65Å; S190-V223 PolarHBondContact OG-O 2.9Å; S190-V223 VanDerWaalsContact OG-O 3.1Å; V223-C225 WeakPolarHBondContact CG1-O 3.45Å; V223-F228 HydrophobicContact CG1-CD1 4.13Å; V223-F228 HydrophobicContact CG1-CE1 3.94Å; V223-F230 HydrophobicContact CG2-CE1 4.32Å; V223-F230 HydrophobicContact CG2-CZ 4.08Å
224P68.3Low80.6Confident98 Ų9880.6 Ų80.664%0.63641%0.41SS*.  trans-77.3-29.6-179.227.5-32.4000114S190S190-P224 VanDerWaalsContact OG-CA 3.32Å; S190-P224 WeakPolarHBondContact OG-CA 3.29Å
225C63.1Low80.9Confident71 Ų7172 Ų7248%0.4837%0.373SS..SBendtrans-131.1145.9-163.4-66.50000113.1V223 K227 F228V223-C225 WeakPolarHBondContact CG1-O 3.45Å; C225-K227 PolarHBondContact O-N 2.9Å; C225-F228 WeakPolarHBondContact O-CE1 3.27Å
226W66.3Low81.2Confident96 Ų9671.6 Ų71.636%0.36437%0.37SS..SBendtrans-65.611.6173-51.492.9000115F189 L240F189-W226 HydrophobicContact CD1-CH2 4.4Å; F189-W226 HydrophobicContact CD1-CZ3 4.4Å; F189-W226 HydrophobicContact CE1-CD2 4.04Å; F189-W226 AromaticContact CE1-CE3 3.54Å; F189-W226 HydrophobicContact CE1-CE3 3.54Å; F189-W226 AromaticContact CE1-CH2 3.83Å; F189-W226 HydrophobicContact CE1-CH2 3.83Å; F189-W226 HydrophobicContact CE1-CZ2 4.28Å; F189-W226 AromaticContact CE1-CZ3 3.42Å; F189-W226 HydrophobicContact CE1-CZ3 3.42Å; F189-W226 VanDerWaalsContact CE1-CZ3 3.42Å; F189-W226 HydrophobicContact CE2-CZ3 4.26Å; F189-W226 AromaticContact CZ-CE3 3.75Å; F189-W226 HydrophobicContact CZ-CE3 3.75Å; F189-W226 AromaticContact CZ-CH2 3.97Å; F189-W226 HydrophobicContact CZ-CH2 3.97Å; F189-W226 AromaticContact CZ-CZ3 3.34Å; F189-W226 HydrophobicContact CZ-CZ3 3.34Å; W226-L240 HydrophobicContact CH2-CD1 3.4Å; W226-L240 HydrophobicContact CZ2-CD1 3.96Å; W226-L240 HydrophobicContact CZ3-CD1 4.44Å
227K72.3Confident81.4Confident188 Ų18866.7 Ų66.782%0.81735%0.347SS*.  trans-106.2104.9174.8-72.7-172.7178.1-177.80107.3C225C225-K227 PolarHBondContact O-N 2.9Å
228F76.4Confident81.5Confident33 Ų3364.9 Ų64.915%0.14534%0.336CS..  trans-104.496.7-174.8-55-59.5000109.6F189 V223 C225 F230 V236 V258 E260F189-F228 HydrophobicContact CE1-CE1 4.44Å; F189-F228 AromaticContact CE1-CZ 3.8Å; F189-F228 HydrophobicContact CE1-CZ 3.8Å; F189-F228 AromaticContact CZ-CZ 3.93Å; F189-F228 HydrophobicContact CZ-CZ 3.93Å; V223-F228 HydrophobicContact CG1-CD1 4.13Å; V223-F228 HydrophobicContact CG1-CE1 3.94Å; C225-F228 WeakPolarHBondContact O-CE1 3.27Å; F228-F230 HydrophobicContact CB-CD2 3.81Å; F228-F230 HydrophobicContact CB-CE2 3.55Å; F228-F230 HydrophobicContact CB-CZ 4.18Å; F228-F230 AromaticContact CD1-CE2 3.63Å; F228-F230 HydrophobicContact CD1-CE2 3.63Å; F228-F230 AromaticContact CD1-CZ 3.67Å; F228-F230 HydrophobicContact CD1-CZ 3.67Å; F228-F230 AromaticContact CG-CE2 3.81Å; F228-F230 HydrophobicContact CG-CE2 3.81Å; F228-F230 HydrophobicContact CG-CZ 4.28Å; F228-F230 PolarHBondContact O-N 2.95Å; F228-V236 HydrophobicContact CD1-CG2 3.81Å; F228-V236 HydrophobicContact CE1-CB 4.15Å; F228-V236 HydrophobicContact CE1-CG1 3.8Å; F228-V236 HydrophobicContact CE1-CG2 3.64Å; F228-V236 HydrophobicContact CG-CG2 4.32Å; F228-V236 HydrophobicContact CZ-CB 4.15Å; F228-V236 HydrophobicContact CZ-CG1 3.92Å; F228-V236 HydrophobicContact CZ-CG2 4Å; F228-V258 HydrophobicContact CB-CG1 4.48Å; F228-V258 HydrophobicContact CB-CG2 3.64Å; F228-V258 HydrophobicContact CD2-CB 4.48Å; F228-V258 HydrophobicContact CD2-CG1 3.97Å; F228-V258 HydrophobicContact CD2-CG2 4.4Å; F228-V258 HydrophobicContact CE2-CG1 4.48Å; F228-V258 HydrophobicContact CG-CG1 4.21Å; F228-V258 HydrophobicContact CG-CG2 4.25Å; F228-E260 HydrophobicContact CE2-CG 3.84Å; F228-E260 WeakPolarHBondContact CE2-OE1 3.32Å; F228-E260 HydrophobicContact CZ-CG 4.49Å
229D74.7Confident81.8Confident155 Ų15561.4 Ų61.483%0.82932%0.32SS*.  trans-9867.4170.9-164.912.3000109.6
230F81.4Confident81.9Confident22 Ų2258.4 Ų58.410%0.09631%0.307CS..  trans-87.8135.9177-57-51.9000110.5Y187 V223 F228 H232 V236 V258Y187-F230 HydrophobicContact CD1-CE1 4.03Å; Y187-F230 HydrophobicContact CD1-CZ 4.23Å; Y187-F230 HydrophobicContact CD2-CE1 4.16Å; Y187-F230 HydrophobicContact CD2-CE2 4.4Å; Y187-F230 AromaticContact CD2-CZ 3.97Å; Y187-F230 HydrophobicContact CD2-CZ 3.97Å; Y187-F230 HydrophobicContact CE1-CD1 4.46Å; Y187-F230 AromaticContact CE1-CE1 3.84Å; Y187-F230 HydrophobicContact CE1-CE1 3.84Å; Y187-F230 HydrophobicContact CE1-CZ 4.45Å; Y187-F230 HydrophobicContact CE2-CD1 4.21Å; Y187-F230 AromaticContact CE2-CE1 3.99Å; Y187-F230 HydrophobicContact CE2-CE1 3.99Å; Y187-F230 HydrophobicContact CE2-CZ 4.22Å; Y187-F230 HydrophobicContact CG-CE1 4.19Å; Y187-F230 AromaticContact CG-CZ 3.99Å; Y187-F230 HydrophobicContact CG-CZ 3.99Å; Y187-F230 AromaticContact CZ-CE1 3.82Å; V223-F230 HydrophobicContact CG2-CE1 4.32Å; V223-F230 HydrophobicContact CG2-CZ 4.08Å; F228-F230 HydrophobicContact CB-CD2 3.81Å; F228-F230 HydrophobicContact CB-CE2 3.55Å; F228-F230 HydrophobicContact CB-CZ 4.18Å; F228-F230 AromaticContact CD1-CE2 3.63Å; F228-F230 HydrophobicContact CD1-CE2 3.63Å; F228-F230 AromaticContact CD1-CZ 3.67Å; F228-F230 HydrophobicContact CD1-CZ 3.67Å; F228-F230 AromaticContact CG-CE2 3.81Å; F228-F230 HydrophobicContact CG-CE2 3.81Å; F228-F230 HydrophobicContact CG-CZ 4.28Å; F228-F230 PolarHBondContact O-N 2.95Å; F230-H232 WeakPolarHBondContact CB-O 3.33Å; F230-H232 PolarHBondContact O-N 3.26Å; F230-V236 HydrophobicContact CE2-CG2 3.54Å; F230-V236 HydrophobicContact CZ-CG2 3.87Å; F230-V258 HydrophobicContact CD2-CG2 3.65Å; F230-V258 HydrophobicContact CE2-CG1 4.29Å; F230-V258 HydrophobicContact CE2-CG2 4.06Å
231A77.2Confident82.1Confident87 Ų8757.5 Ų57.572%0.71931%0.311SS*.SBendtrans-70.3-17172.400000113.2
232H80.7Confident82.8Confident91 Ų9155.9 Ų55.942%0.42130%0.299SS..SBendtrans-135.1151.4-173.9-49.478.4000110.6F230 S234F230-H232 WeakPolarHBondContact CB-O 3.33Å; F230-H232 PolarHBondContact O-N 3.26Å; H232-S234 PolarHBondContact O-N 3.49Å; H232-S234 PolarHBondContact O-OG 3.11Å
233P83.3Confident83.4Confident42 Ų4258.1 Ų58.127%0.27330%0.301SS..  trans-51.1122.4171.5-23.532.4000111F177 S178 K257F177-P233 HydrophobicContact CE1-CB 4.28Å; F177-P233 HydrophobicContact CE2-CB 3.69Å; F177-P233 HydrophobicContact CZ-CB 3.53Å; S178-P233 WeakPolarHBondContact O-CG 3.47Å; P233-K257 WeakPolarHBondContact CA-O 3.36Å
234S90.8Very high84.1Confident1 Ų159.1 Ų59.11%0.00730%0.304CS..EExtended strand (participates in β ladder)trans-139.1153.9-172.5-580000111.7K185 H232 K257 V258 I259K185-S234 CarbonylContact O-C 3.57Å; K185-S234 WeakPolarHBondContact O-CA 3.28Å; H232-S234 PolarHBondContact O-N 3.49Å; H232-S234 PolarHBondContact O-OG 3.11Å; S234-K257 PolarHBondContact N-O 3.28Å; S234-V258 VanDerWaalsContact O-CA 3.29Å; S234-V258 WeakPolarHBondContact O-CA 3.31Å; S234-I259 PolarHBondContact O-N 3.39Å
235V93.2Very high85.2Confident0 Ų060.2 Ų60.20%031%0.308CS..EExtended strand (participates in β ladder)trans-103.3134.6171.1176.60000108.2L184 K185 V186 Y187 W203 C237 I259 L276L184-V235 HydrophobicContact CD1-CG2 3.64Å; L184-V235 HydrophobicContact CD2-CG2 3.89Å; L184-V235 HydrophobicContact CG-CG2 3.82Å; K185-V235 PolarHBondContact O-N 2.87Å; V186-V235 CarbonylContact C-O 3.55Å; V186-V235 WeakPolarHBondContact CA-O 3.42Å; V186-V235 HydrophobicContact CG2-CB 4.24Å; Y187-V235 PolarHBondContact N-O 3.22Å; W203-V235 HydrophobicContact CH2-CG1 4.23Å; W203-V235 HydrophobicContact CZ2-CG1 4.15Å; V235-C237 HydrophobicContact CG1-CB 4.42Å; V235-I259 CarbonylContact C-O 3.46Å; V235-I259 VanDerWaalsContact CA-O 3.28Å; V235-I259 WeakPolarHBondContact CA-O 3.31Å; V235-I259 HydrophobicContact CG2-CB 4.12Å; V235-L276 HydrophobicContact CG1-CD2 4.48Å; V235-L276 HydrophobicContact CG2-CD2 4.21Å
236V93.6Very high86.6Confident0 Ų062.9 Ų62.90%031%0.308CS..EExtended strand (participates in β ladder)trans-115.5122.3169.9-172.10000107.3Y187 F189 F228 F230 V258 I259 E260 L261Y187-V236 CarbonylContact O-C 3.59Å; Y187-V236 WeakPolarHBondContact O-CA 3.43Å; F189-V236 HydrophobicContact CD1-CG1 4.17Å; F189-V236 HydrophobicContact CD2-CG1 3.94Å; F189-V236 HydrophobicContact CE1-CG1 3.88Å; F189-V236 HydrophobicContact CE2-CB 4.32Å; F189-V236 HydrophobicContact CE2-CG1 3.6Å; F189-V236 HydrophobicContact CG-CG1 4.2Å; F189-V236 HydrophobicContact CZ-CB 4.31Å; F189-V236 HydrophobicContact CZ-CG1 3.57Å; F228-V236 HydrophobicContact CD1-CG2 3.81Å; F228-V236 HydrophobicContact CE1-CB 4.15Å; F228-V236 HydrophobicContact CE1-CG1 3.8Å; F228-V236 HydrophobicContact CE1-CG2 3.64Å; F228-V236 HydrophobicContact CG-CG2 4.32Å; F228-V236 HydrophobicContact CZ-CB 4.15Å; F228-V236 HydrophobicContact CZ-CG1 3.92Å; F228-V236 HydrophobicContact CZ-CG2 4Å; F230-V236 HydrophobicContact CE2-CG2 3.54Å; F230-V236 HydrophobicContact CZ-CG2 3.87Å; V236-V258 HydrophobicContact CB-CG1 4.45Å; V236-V258 HydrophobicContact CG2-CG1 3.71Å; V236-I259 PolarHBondContact N-O 3.36Å; V236-E260 CarbonylContact O-C 3.48Å; V236-E260 WeakPolarHBondContact O-CA 3.34Å; V236-L261 PolarHBondContact O-N 2.97Å
237C94.7Very high87.9Confident0 Ų067.5 Ų67.50%033%0.326CS..EExtended strand (participates in β ladder)trans-133.2157.3-177.170.80000114.3Y187 F188 F189 W203 V235 L261 L269Y187-C237 PolarHBondContact O-N 3.21Å; F188-C237 CarbonylContact C-O 3.59Å; F188-C237 VanDerWaalsContact CA-O 3.29Å; F188-C237 WeakPolarHBondContact CA-O 3.4Å; F189-C237 PolarHBondContact N-O 3.44Å; W203-C237 HydrophobicContact CZ2-CB 4.45Å; W203-C237 PolarHBondContact NE1-SG 3.33Å; V235-C237 HydrophobicContact CG1-CB 4.42Å; C237-L261 WeakPolarHBondContact CA-O 3.26Å; C237-L261 HydrophobicContact CB-CB 4.01Å; C237-L261 HydrophobicContact CB-CD2 4.43Å; C237-L261 HydrophobicContact CB-CG 4.25Å; C237-L261 WeakPolarHBondContact CB-O 3.39Å; C237-L269 HydrophobicContact CB-CD1 4.36Å
238G92.9Very high89Confident0 Ų060.3 Ų60.30%030%0.295CS..EExtended strand (participates in β ladder)trans175.6166178.400000113.2L261 I262 A263G238-L261 PolarHBondContact N-O 3.09Å; G238-I262 WeakPolarHBondContact O-CA 3.29Å; G238-A263 PolarHBondContact O-N 2.91Å; G238-A263 VanDerWaalsContact O-N 3.09Å
239V95.8Very high90Very high1 Ų159 Ų591%0.00629%0.289CS..EExtended strand (participates in β ladder)trans-97.7116.7178.3-175.50000108.4S192 T193 V199 A263 S264 L266S192-V239 CarbonylContact C-O 3.49Å; S192-V239 VanDerWaalsContact CA-O 3.23Å; S192-V239 WeakPolarHBondContact CA-O 3.44Å; S192-V239 PolarHBondContact OG-N 2.82Å; S192-V239 VanDerWaalsContact OG-N 3.11Å; S192-V239 PolarHBondContact OG-O 3.39Å; T193-V239 PolarHBondContact N-O 2.99Å; T193-V239 VanDerWaalsContact OG1-CG1 3.26Å; T193-V239 WeakPolarHBondContact OG1-CG1 3.39Å; T193-V239 PolarHBondContact OG1-O 3.44Å; V199-V239 HydrophobicContact CG2-CG2 4.24Å; V239-A263 CarbonylContact C-O 3.21Å; V239-A263 WeakPolarHBondContact CA-O 3.46Å; V239-S264 WeakPolarHBondContact CG1-O 3.47Å; V239-L266 HydrophobicContact CG2-CD2 3.97Å
240L93.7Very high91.1Very high0 Ų051.7 Ų51.70%025%0.25CS..  trans-129.771.8-177.1-60.4176.3000109F189 N191 W226 Y242 R243 I262 A263F189-L240 HydrophobicContact CD2-CD1 4.43Å; N191-L240 WeakPolarHBondContact O-CD2 3.4Å; W226-L240 HydrophobicContact CH2-CD1 3.4Å; W226-L240 HydrophobicContact CZ2-CD1 3.96Å; W226-L240 HydrophobicContact CZ3-CD1 4.44Å; L240-Y242 HydrophobicContact CB-CD1 4.35Å; L240-Y242 HydrophobicContact CB-CE1 3.85Å; L240-Y242 HydrophobicContact CD2-CE1 3.89Å; L240-Y242 HydrophobicContact CG-CE1 4.36Å; L240-Y242 PolarHBondContact O-N 2.85Å; L240-R243 HydrophobicContact CB-CG 4.04Å; L240-R243 WeakPolarHBondContact O-CB 3.08Å; L240-R243 PolarHBondContact O-N 2.75Å; L240-I262 HydrophobicContact CD1-CB 4.3Å; L240-I262 HydrophobicContact CD1-CG2 3.74Å; L240-A263 PolarHBondContact N-O 3.27Å
241A92.2Very high91.9Very high43 Ų4351 Ų5136%0.35525%0.248SC..G310 helixtrans-49.5-38.8-173.400000113.8T193 R243 F244 S264T193-A241 HydrophobicContact CG2-CB 4.33Å; A241-R243 PolarHBondContact O-N 2.7Å; A241-F244 PolarHBondContact O-N 2.89Å; A241-S264 WeakPolarHBondContact CA-O 3.34Å; A241-S264 WeakPolarHBondContact CB-O 3.35Å
242Y91Very high92.9Very high140 Ų14046.9 Ų46.955%0.54921%0.213SC..G310 helixtrans-63-13.3-18072-89.5000114.9L240L240-Y242 HydrophobicContact CB-CD1 4.35Å; L240-Y242 HydrophobicContact CB-CE1 3.85Å; L240-Y242 HydrophobicContact CD2-CE1 3.89Å; L240-Y242 HydrophobicContact CG-CE1 4.36Å; L240-Y242 PolarHBondContact O-N 2.85Å
243R90.5Very high93.6Very high134 Ų13443.7 Ų43.751%0.50620%0.201SC..G310 helixtrans-85.3-10.6176.3-67.8-69-168.2138.93.1113.2L240 A241 I262L240-R243 HydrophobicContact CB-CG 4.04Å; L240-R243 WeakPolarHBondContact O-CB 3.08Å; L240-R243 PolarHBondContact O-N 2.75Å; A241-R243 PolarHBondContact O-N 2.7Å; R243-I262 HydrophobicContact CB-CD1 4.46Å; R243-I262 HydrophobicContact CG-CD1 4.44Å
244F93.6Very high94.1Very high40 Ų4041.9 Ų41.918%0.17519%0.189CC..  trans-124.7135.1-171-63.6-86.5000110.9A241 D251 I262A241-F244 PolarHBondContact O-N 2.89Å; F244-D251 HydrophobicContact CE1-CB 4.09Å; F244-D251 HydrophobicContact CZ-CB 3.92Å; F244-I262 HydrophobicContact CE2-CB 4.42Å; F244-I262 HydrophobicContact CE2-CD1 4.31Å; F244-I262 HydrophobicContact CE2-CG1 4.2Å; F244-I262 HydrophobicContact CZ-CD1 4.2Å; F244-I262 HydrophobicContact CZ-CG1 3.93Å; F244-I262 WeakPolarHBondContact CZ-O 3.33Å
245V91.3Very high94.1Very high120 Ų12046.2 Ų46.273%0.72721%0.207SC*.SBendtrans-81.3-32172.5-178.10000110.6
246R92.5Very high93.8Very high127 Ų12750.6 Ų50.648%0.47923%0.228SC..SBendtrans-105.3147.8-175.9-64.5178.7-174.4-165.3-2110.1S249 S264R246-S249 VanDerWaalsContact CB-OG 3.26Å; R246-S249 WeakPolarHBondContact CB-OG 3.42Å; R246-S249 WeakPolarHBondContact O-CB 3.46Å; R246-S249 PolarHBondContact O-OG 3.28Å; R246-S249 VanDerWaalsContact O-OG 3.07Å; R246-S264 WeakPolarHBondContact O-CB 3.23Å
247R93Very high93.5Very high194 Ų19455.5 Ų55.573%0.73225%0.249SC*.THydrogen-bonded Turntrans-73.5169.4168.1-64.7-172.1179.8-164.7-0.6110.5S249R247-S249 PolarHBondContact O-N 3.23Å; R247-S249 PolarHBondContact O-OG 3.33Å
248E96.1Very high93.3Very high37 Ų3755.9 Ų55.917%0.17325%0.251CS..THydrogen-bonded Turntrans52.724.1-179.7-61.4-179.8-158.200113.7S264 D265 V267 Y271 P304 R309E248-S264 PolarHBondContact N-OG 3.28Å; E248-D265 PolarHBondContact N-OD2 3.32Å; E248-V267 HydrophobicContact CG-CB 4.26Å; E248-V267 HydrophobicContact CG-CG1 3.89Å; E248-Y271 HydrophobicContact CB-CD2 4.36Å; E248-Y271 HydrophobicContact CB-CE2 4.02Å; E248-Y271 HydrophobicContact CG-CE2 4.3Å; E248-P304 HydrophobicContact CB-CG 4Å; E248-R309 IonicContact OE2-CZ 3.9Å; E248-R309 IonicContact OE2-NH1 3.9Å; E248-R309 PolarHBondContact OE2-NH1 2.85Å; E248-R309 IonicContact OE2-NH2 3.81Å; E248-R309 PolarHBondContact OE2-NH2 3.43Å
249S97.8Very high93.4Very high4 Ų456 Ų563%0.02825%0.252CS..  trans-101.8151-173.8-60.30000110.5R246 R247 A263 S264 D302 W303R246-S249 VanDerWaalsContact CB-OG 3.26Å; R246-S249 WeakPolarHBondContact CB-OG 3.42Å; R246-S249 WeakPolarHBondContact O-CB 3.46Å; R246-S249 PolarHBondContact O-OG 3.28Å; R246-S249 VanDerWaalsContact O-OG 3.07Å; R247-S249 PolarHBondContact O-N 3.23Å; R247-S249 PolarHBondContact O-OG 3.33Å; S249-A263 CarbonylContact O-C 3.6Å; S249-A263 WeakPolarHBondContact O-CA 3.36Å; S249-S264 PolarHBondContact N-OG 3.08Å; S249-S264 PolarHBondContact O-N 2.66Å; S249-S264 PolarHBondContact O-OG 2.76Å; S249-D302 WeakPolarHBondContact CA-O 3.4Å; S249-W303 WeakPolarHBondContact OG-CB 3.36Å
250Y98.2Very high93.3Very high3 Ų356.8 Ų56.81%0.01226%0.256CS..EExtended strand (participates in β ladder)trans-146.1159.3175.668.2-94.6000112.1I252 L261 I262 G268 A275 I300 D302 K337 W553Y250-I252 HydrophobicContact CD2-CD1 4.05Å; Y250-I252 HydrophobicContact CD2-CG1 3.94Å; Y250-I252 HydrophobicContact CE2-CD1 3.75Å; Y250-I252 HydrophobicContact CE2-CG1 4.1Å; Y250-L261 HydrophobicContact CD2-CD1 4.44Å; Y250-I262 CarbonylContact C-O 3.53Å; Y250-I262 VanDerWaalsContact CA-O 3.3Å; Y250-I262 WeakPolarHBondContact CA-O 3.32Å; Y250-G268 WeakPolarHBondContact CB-O 3.14Å; Y250-A275 HydrophobicContact CE2-CB 4.06Å; Y250-A275 VanDerWaalsContact OH-CB 3.24Å; Y250-A275 WeakPolarHBondContact OH-CB 3.46Å; Y250-I300 HydrophobicContact CE2-CG2 4.01Å; Y250-D302 HydrophobicContact CD1-CB 4.4Å; Y250-D302 HydrophobicContact CD2-CB 4.44Å; Y250-D302 HydrophobicContact CE1-CB 3.79Å; Y250-D302 HydrophobicContact CE2-CB 3.83Å; Y250-D302 VanDerWaalsContact CZ-CB 3.48Å; Y250-D302 PolarHBondContact N-O 3.42Å; Y250-D302 PolarHBondContact O-N 2.91Å; Y250-D302 PolarHBondContact OH-OD2 3.23Å; Y250-K337 PolarHBondContact OH-NZ 3.11Å; Y250-W553 HydrophobicContact CE1-CH2 4.28Å; Y250-W553 AromaticContact CE1-CZ2 3.91Å; Y250-W553 HydrophobicContact CE1-CZ2 3.91Å
251D97.9Very high93.5Very high7 Ų756.8 Ų56.84%0.03726%0.256CS..EExtended strand (participates in β ladder)trans-133.3121.1175.9-172.3-27.6000108.4F244 T253 L261 I262 R299 I300 R301F244-D251 HydrophobicContact CE1-CB 4.09Å; F244-D251 HydrophobicContact CZ-CB 3.92Å; D251-T253 PolarHBondContact OD1-OG1 3.5Å; D251-L261 WeakPolarHBondContact O-CA 3.39Å; D251-I262 HydrophobicContact CB-CD1 4.12Å; D251-I262 HydrophobicContact CB-CG1 3.72Å; D251-I262 PolarHBondContact N-O 2.81Å; D251-I262 PolarHBondContact O-N 3.07Å; D251-R299 WeakPolarHBondContact OD1-CG 3.32Å; D251-R299 IonicContact OD1-NE 2.77Å; D251-R299 PolarHBondContact OD1-NE 3.35Å; D251-R299 VanDerWaalsContact OD1-NE 3.13Å; D251-R299 IonicContact OD2-CZ 3.25Å; D251-R299 VanDerWaalsContact OD2-CZ 3.23Å; D251-R299 IonicContact OD2-NE 2.87Å; D251-R299 PolarHBondContact OD2-NE 3.41Å; D251-R299 IonicContact OD2-NH2 3.18Å; D251-R299 PolarHBondContact OD2-NH2 2.89Å; D251-I300 CarbonylContact C-O 3.56Å; D251-I300 VanDerWaalsContact CA-O 3.26Å; D251-I300 WeakPolarHBondContact CA-O 3.45Å; D251-R301 HydrophobicContact CB-CG 4.3Å; D251-R301 WeakPolarHBondContact OD2-CG 3.21Å
252I97.7Very high93.7Very high0 Ų055.6 Ų55.60%024%0.243CC..EExtended strand (participates in β ladder)trans-108.9116.3173.1-62.7168.1000107.3Y250 V254 I259 E260 L261 G272 A275 L276 M279 R299 I300Y250-I252 HydrophobicContact CD2-CD1 4.05Å; Y250-I252 HydrophobicContact CD2-CG1 3.94Å; Y250-I252 HydrophobicContact CE2-CD1 3.75Å; Y250-I252 HydrophobicContact CE2-CG1 4.1Å; I252-V254 HydrophobicContact CG2-CG2 4.18Å; I252-I259 HydrophobicContact CG2-CG2 3.88Å; I252-E260 CarbonylContact C-O 3.53Å; I252-E260 VanDerWaalsContact CA-O 3.29Å; I252-E260 WeakPolarHBondContact CA-O 3.33Å; I252-L261 HydrophobicContact CD1-CD1 4.33Å; I252-L261 HydrophobicContact CG1-CD1 3.63Å; I252-G272 WeakPolarHBondContact CD1-O 3.47Å; I252-A275 HydrophobicContact CD1-CB 3.94Å; I252-L276 HydrophobicContact CD1-CB 4.41Å; I252-M279 HydrophobicContact CD1-SD 4.32Å; I252-M279 HydrophobicContact CG2-CE 4.37Å; I252-M279 HydrophobicContact CG2-SD 4.47Å; I252-R299 CarbonylContact O-C 3.57Å; I252-R299 VanDerWaalsContact O-CA 3.25Å; I252-R299 WeakPolarHBondContact O-CA 3.48Å; I252-I300 HydrophobicContact CB-CB 4.39Å; I252-I300 PolarHBondContact N-O 3.47Å; I252-I300 PolarHBondContact O-N 3.45Å
253T95.4Very high94Very high25 Ų2548.9 Ų48.915%0.15322%0.217CC..EExtended strand (participates in β ladder)trans-113.3117173.1-61.70000109.5D251 K255 I259 E260 R299D251-T253 PolarHBondContact OD1-OG1 3.5Å; T253-K255 HydrophobicContact CG2-CG 4.2Å; T253-I259 WeakPolarHBondContact O-CA 3.34Å; T253-E260 PolarHBondContact N-O 2.84Å; T253-E260 PolarHBondContact O-N 3.38Å; T253-R299 WeakPolarHBondContact OG1-CD 3.49Å; T253-R299 WeakPolarHBondContact OG1-CG 3.44Å
254V93.5Very high94.3Very high4 Ų443 Ų432%0.02420%0.196CC..EExtended strand (participates in β ladder)trans-95.9115.5179.2-178.30000109F177 I252 I259 M279 L295 L298F177-V254 HydrophobicContact CB-CG1 3.66Å; F177-V254 HydrophobicContact CG-CG1 4.33Å; I252-V254 HydrophobicContact CG2-CG2 4.18Å; V254-I259 HydrophobicContact CG1-CG1 4.38Å; V254-I259 HydrophobicContact CG2-CG1 4.43Å; V254-M279 HydrophobicContact CG2-CE 3.82Å; V254-L295 HydrophobicContact CB-CD2 4.2Å; V254-L295 HydrophobicContact CG1-CB 4.49Å; V254-L295 HydrophobicContact CG1-CD2 3.57Å; V254-L295 HydrophobicContact CG1-CG 3.95Å; V254-L295 HydrophobicContact CG2-CD2 3.54Å; V254-L295 HydrophobicContact CG2-CG 4.31Å; V254-L298 HydrophobicContact CB-CD1 4.5Å; V254-L298 HydrophobicContact CB-CG 4.15Å; V254-L298 HydrophobicContact CG2-CD1 3.8Å; V254-L298 HydrophobicContact CG2-CG 3.85Å; V254-L298 PolarHBondContact N-O 2.69Å; V254-L298 PolarHBondContact O-N 3.48Å
255K91.2Very high94.4Very high91 Ų9143 Ų4340%0.39620%0.198SC..  trans-112.3169.9173.1-59.3179179.9171.70109.4F177 T253 K257 V258 E260F177-K255 WeakPolarHBondContact CD2-O 3.49Å; T253-K255 HydrophobicContact CG2-CG 4.2Å; K255-K257 VanDerWaalsContact C-N 3.29Å; K255-K257 PolarHBondContact O-N 3.33Å; K255-K257 VanDerWaalsContact O-N 3.15Å; K255-V258 WeakPolarHBondContact CA-O 3.42Å; K255-V258 WeakPolarHBondContact CB-O 3.31Å; K255-V258 PolarHBondContact N-O 3.47Å; K255-V258 PolarHBondContact O-N 3.02Å; K255-E260 VanDerWaalsContact CE-OE1 3.23Å; K255-E260 WeakPolarHBondContact CE-OE1 3.4Å; K255-E260 IonicContact NZ-OE1 3.73Å; K255-E260 PolarHBondContact NZ-OE1 3.44Å; K255-E260 IonicContact NZ-OE2 2.96Å
256E87.1Confident94.7Very high93 Ų9339.9 Ų39.944%0.43518%0.177SC..SBendtrans-52.3-41-175.4-172-179-18000114.2Q175Q175-E256 HydrophobicContact CB-CG 4.42Å; Q175-E256 PolarHBondContact NE2-OE2 3.47Å
257K87.2Confident94.9Very high103 Ų10335.8 Ų35.845%0.44817%0.166SC..SBendtrans-114.9-8.8-179.2-63.8-174.9179.6-1790114.4P233 S234 K255P233-K257 WeakPolarHBondContact CA-O 3.36Å; S234-K257 PolarHBondContact N-O 3.28Å; K255-K257 VanDerWaalsContact C-N 3.29Å; K255-K257 PolarHBondContact O-N 3.33Å; K255-K257 VanDerWaalsContact O-N 3.15Å
258V91.3Very high95.1Very high7 Ų726.6 Ų26.64%0.04213%0.131CC..EExtended strand (participates in β ladder)trans-141133.6-167.3-1710000111.6F228 F230 S234 V236 K255 E260F228-V258 HydrophobicContact CB-CG1 4.48Å; F228-V258 HydrophobicContact CB-CG2 3.64Å; F228-V258 HydrophobicContact CD2-CB 4.48Å; F228-V258 HydrophobicContact CD2-CG1 3.97Å; F228-V258 HydrophobicContact CD2-CG2 4.4Å; F228-V258 HydrophobicContact CE2-CG1 4.48Å; F228-V258 HydrophobicContact CG-CG1 4.21Å; F228-V258 HydrophobicContact CG-CG2 4.25Å; F230-V258 HydrophobicContact CD2-CG2 3.65Å; F230-V258 HydrophobicContact CE2-CG1 4.29Å; F230-V258 HydrophobicContact CE2-CG2 4.06Å; S234-V258 VanDerWaalsContact O-CA 3.29Å; S234-V258 WeakPolarHBondContact O-CA 3.31Å; V236-V258 HydrophobicContact CB-CG1 4.45Å; V236-V258 HydrophobicContact CG2-CG1 3.71Å; K255-V258 WeakPolarHBondContact CA-O 3.42Å; K255-V258 WeakPolarHBondContact CB-O 3.31Å; K255-V258 PolarHBondContact N-O 3.47Å; K255-V258 PolarHBondContact O-N 3.02Å; V258-E260 HydrophobicContact CG1-CG 4.13Å
259I94.4Very high95.1Very high2 Ų224.8 Ų24.81%0.0112%0.123CC..EExtended strand (participates in β ladder)trans-104115.4165.3-60.4177.3000107.8F177 S234 V235 V236 I252 T253 V254 L276 L295F177-I259 HydrophobicContact CD1-CD1 3.89Å; F177-I259 HydrophobicContact CD1-CG1 4.31Å; F177-I259 HydrophobicContact CD2-CD1 4.41Å; F177-I259 HydrophobicContact CD2-CG1 3.95Å; F177-I259 HydrophobicContact CE1-CD1 3.6Å; F177-I259 HydrophobicContact CE1-CG1 4.16Å; F177-I259 HydrophobicContact CE2-CD1 4.13Å; F177-I259 HydrophobicContact CE2-CG1 3.76Å; F177-I259 HydrophobicContact CG-CD1 4.28Å; F177-I259 HydrophobicContact CG-CG1 4.21Å; F177-I259 HydrophobicContact CZ-CD1 3.72Å; F177-I259 HydrophobicContact CZ-CG1 3.87Å; S234-I259 PolarHBondContact O-N 3.39Å; V235-I259 CarbonylContact C-O 3.46Å; V235-I259 VanDerWaalsContact CA-O 3.28Å; V235-I259 WeakPolarHBondContact CA-O 3.31Å; V235-I259 HydrophobicContact CG2-CB 4.12Å; V236-I259 PolarHBondContact N-O 3.36Å; I252-I259 HydrophobicContact CG2-CG2 3.88Å; T253-I259 WeakPolarHBondContact O-CA 3.34Å; V254-I259 HydrophobicContact CG1-CG1 4.38Å; V254-I259 HydrophobicContact CG2-CG1 4.43Å; I259-L276 HydrophobicContact CD1-CD1 3.87Å; I259-L276 HydrophobicContact CG2-CD1 4Å; I259-L295 HydrophobicContact CD1-CD2 4.09Å
260E94.7Very high95.1Very high19 Ų1924.6 Ų24.69%0.08912%0.122CC..EExtended strand (participates in β ladder)trans-92.1117.7174.3-68168.4-152.500108.7F228 V236 I252 T253 K255 V258F228-E260 HydrophobicContact CE2-CG 3.84Å; F228-E260 WeakPolarHBondContact CE2-OE1 3.32Å; F228-E260 HydrophobicContact CZ-CG 4.49Å; V236-E260 CarbonylContact O-C 3.48Å; V236-E260 WeakPolarHBondContact O-CA 3.34Å; I252-E260 CarbonylContact C-O 3.53Å; I252-E260 VanDerWaalsContact CA-O 3.29Å; I252-E260 WeakPolarHBondContact CA-O 3.33Å; T253-E260 PolarHBondContact N-O 2.84Å; T253-E260 PolarHBondContact O-N 3.38Å; K255-E260 VanDerWaalsContact CE-OE1 3.23Å; K255-E260 WeakPolarHBondContact CE-OE1 3.4Å; K255-E260 IonicContact NZ-OE1 3.73Å; K255-E260 PolarHBondContact NZ-OE1 3.44Å; K255-E260 IonicContact NZ-OE2 2.96Å; V258-E260 HydrophobicContact CG1-CG 4.13Å
261L97Very high95.1Very high0 Ų024.7 Ų24.70%012%0.122CC..EExtended strand (participates in β ladder)trans-115.9100.6175.1168.458.3000109.7W203 V236 C237 G238 Y250 D251 I252 L269 I273W203-L261 HydrophobicContact CZ2-CD2 4.36Å; V236-L261 PolarHBondContact O-N 2.97Å; C237-L261 WeakPolarHBondContact CA-O 3.26Å; C237-L261 HydrophobicContact CB-CB 4.01Å; C237-L261 HydrophobicContact CB-CD2 4.43Å; C237-L261 HydrophobicContact CB-CG 4.25Å; C237-L261 WeakPolarHBondContact CB-O 3.39Å; G238-L261 PolarHBondContact N-O 3.09Å; Y250-L261 HydrophobicContact CD2-CD1 4.44Å; D251-L261 WeakPolarHBondContact O-CA 3.39Å; I252-L261 HydrophobicContact CD1-CD1 4.33Å; I252-L261 HydrophobicContact CG1-CD1 3.63Å; L261-L269 HydrophobicContact CD2-CD1 3.94Å; L261-L269 HydrophobicContact CG-CD1 4.05Å; L261-I273 HydrophobicContact CD2-CG1 3.85Å
262I95.9Very high95.1Very high17 Ų1724.3 Ų24.39%0.08712%0.12CC..EExtended strand (participates in β ladder)trans-109.6144176.758168.5000109.8F189 G238 L240 R243 F244 Y250 D251F189-I262 HydrophobicContact CD2-CG2 4.03Å; F189-I262 HydrophobicContact CE2-CG2 3.44Å; F189-I262 VanDerWaalsContact CE2-CG2 3.44Å; F189-I262 HydrophobicContact CZ-CG2 4.15Å; G238-I262 WeakPolarHBondContact O-CA 3.29Å; L240-I262 HydrophobicContact CD1-CB 4.3Å; L240-I262 HydrophobicContact CD1-CG2 3.74Å; R243-I262 HydrophobicContact CB-CD1 4.46Å; R243-I262 HydrophobicContact CG-CD1 4.44Å; F244-I262 HydrophobicContact CE2-CB 4.42Å; F244-I262 HydrophobicContact CE2-CD1 4.31Å; F244-I262 HydrophobicContact CE2-CG1 4.2Å; F244-I262 HydrophobicContact CZ-CD1 4.2Å; F244-I262 HydrophobicContact CZ-CG1 3.93Å; F244-I262 WeakPolarHBondContact CZ-O 3.33Å; Y250-I262 CarbonylContact C-O 3.53Å; Y250-I262 VanDerWaalsContact CA-O 3.3Å; Y250-I262 WeakPolarHBondContact CA-O 3.32Å; D251-I262 HydrophobicContact CB-CD1 4.12Å; D251-I262 HydrophobicContact CB-CG1 3.72Å; D251-I262 PolarHBondContact N-O 2.81Å; D251-I262 PolarHBondContact O-N 3.07Å
263A97.9Very high95Very high0 Ų024.3 Ų24.30%012%0.12CC..EExtended strand (participates in β ladder)trans-134.1159.5-179.600000112.8G238 V239 L240 S249 D265 L269G238-A263 PolarHBondContact O-N 2.91Å; G238-A263 VanDerWaalsContact O-N 3.09Å; V239-A263 CarbonylContact C-O 3.21Å; V239-A263 WeakPolarHBondContact CA-O 3.46Å; L240-A263 PolarHBondContact N-O 3.27Å; S249-A263 CarbonylContact O-C 3.6Å; S249-A263 WeakPolarHBondContact O-CA 3.36Å; A263-D265 WeakPolarHBondContact CB-O 3.36Å; A263-L269 HydrophobicContact CB-CB 3.77Å
264S96.9Very high95.1Very high11 Ų1123.4 Ų23.48%0.07711%0.114CC..SBendtrans-72.2-35.9175.862.40000112.6V239 A241 R246 E248 S249V239-S264 WeakPolarHBondContact CG1-O 3.47Å; A241-S264 WeakPolarHBondContact CA-O 3.34Å; A241-S264 WeakPolarHBondContact CB-O 3.35Å; R246-S264 WeakPolarHBondContact O-CB 3.23Å; E248-S264 PolarHBondContact N-OG 3.28Å; S249-S264 PolarHBondContact N-OG 3.08Å; S249-S264 PolarHBondContact O-N 2.66Å; S249-S264 PolarHBondContact O-OG 2.76Å
265D96.4Very high95.2Very high38 Ų3823.4 Ų23.420%0.20312%0.115CC..SBendtrans-153.5178.6-176.75048.5000109.8E248 A263 V267 G268 L269E248-D265 PolarHBondContact N-OD2 3.32Å; A263-D265 WeakPolarHBondContact CB-O 3.36Å; D265-V267 PolarHBondContact O-N 3.19Å; D265-V267 PolarHBondContact OD1-N 3.04Å; D265-G268 PolarHBondContact O-N 3.19Å; D265-G268 PolarHBondContact OD1-N 3.41Å; D265-L269 PolarHBondContact O-N 3.21Å
266L96.5Very high95.4Very high55 Ų5519.1 Ų19.129%0.28810%0.096SC..Hα-helixtrans-64.1-29.3179.4-66.3172.5000112.8D198 V199 V202 V239 L269 G270 Q373D198-L266 HydrophobicContact CB-CD1 3.97Å; D198-L266 HydrophobicContact CB-CD2 4.02Å; V199-L266 HydrophobicContact CG2-CD2 4.38Å; V202-L266 HydrophobicContact CG2-CB 4.34Å; V202-L266 HydrophobicContact CG2-CD2 4.19Å; V239-L266 HydrophobicContact CG2-CD2 3.97Å; L266-L269 WeakPolarHBondContact O-CB 3.28Å; L266-L269 PolarHBondContact O-N 3.48Å; L266-G270 PolarHBondContact O-N 3.09Å; L266-G270 VanDerWaalsContact O-N 3.07Å; L266-Q373 PolarHBondContact O-NE2 3.29Å
267V96.7Very high95.7Very high42 Ų4215 Ų1526%0.2558%0.077SC..Hα-helixtrans-71.4-48.1179.2-1790000110.2E248 D265 L269 G270 Y271 Q373E248-V267 HydrophobicContact CG-CB 4.26Å; E248-V267 HydrophobicContact CG-CG1 3.89Å; D265-V267 PolarHBondContact O-N 3.19Å; D265-V267 PolarHBondContact OD1-N 3.04Å; V267-L269 PolarHBondContact O-N 2.65Å; V267-G270 PolarHBondContact O-N 3.21Å; V267-Y271 HydrophobicContact CG1-CD2 4.25Å; V267-Y271 HydrophobicContact CG1-CE1 4.39Å; V267-Y271 HydrophobicContact CG1-CE2 3.5Å; V267-Y271 VanDerWaalsContact CG1-CE2 3.5Å; V267-Y271 PolarHBondContact O-N 3.12Å; V267-Q373 HydrophobicContact CG1-CB 4.32Å; V267-Q373 HydrophobicContact CG2-CB 4.45Å; V267-Q373 HydrophobicContact CG2-CG 4.49Å; V267-Q373 PolarHBondContact O-OE1 3.41Å
268G97Very high95.9Very high0 Ų010.3 Ų10.30%06%0.057CC..Hα-helixtrans-57.9-37.317200000112.2Y250 D265 Y271 G272Y250-G268 WeakPolarHBondContact CB-O 3.14Å; D265-G268 PolarHBondContact O-N 3.19Å; D265-G268 PolarHBondContact OD1-N 3.41Å; G268-Y271 PolarHBondContact O-N 3.35Å; G268-G272 PolarHBondContact O-N 3.37Å
269L97.4Very high95.8Very high0 Ų010 Ų100%06%0.055CC..Hα-helixtrans-61.7-45.2174176.568.4000111.3V199 V202 C237 L261 A263 D265 L266 V267 Y271 G272 I273V199-L269 HydrophobicContact CB-CD2 4.25Å; V199-L269 HydrophobicContact CG1-CD2 3.74Å; V199-L269 HydrophobicContact CG2-CD2 4.29Å; V202-L269 HydrophobicContact CB-CD2 4.24Å; V202-L269 HydrophobicContact CG1-CD2 4.43Å; V202-L269 HydrophobicContact CG1-CG 4.5Å; V202-L269 HydrophobicContact CG2-CD2 4.39Å; C237-L269 HydrophobicContact CB-CD1 4.36Å; L261-L269 HydrophobicContact CD2-CD1 3.94Å; L261-L269 HydrophobicContact CG-CD1 4.05Å; A263-L269 HydrophobicContact CB-CB 3.77Å; D265-L269 PolarHBondContact O-N 3.21Å; L266-L269 WeakPolarHBondContact O-CB 3.28Å; L266-L269 PolarHBondContact O-N 3.48Å; V267-L269 PolarHBondContact O-N 2.65Å; L269-Y271 VanDerWaalsContact C-N 3.34Å; L269-Y271 PolarHBondContact O-N 3.28Å; L269-G272 PolarHBondContact O-N 3.38Å; L269-I273 HydrophobicContact CD1-CD1 4.44Å; L269-I273 HydrophobicContact CG-CD1 4.12Å; L269-I273 WeakPolarHBondContact O-CG1 3.33Å; L269-I273 PolarHBondContact O-N 3.16Å
270G97.1Very high95.5Very high0 Ų010 Ų100%06%0.055CC..Hα-helixtrans-57.9-46.5175.500000111.7L266 V267 G272 I273 H274L266-G270 PolarHBondContact O-N 3.09Å; L266-G270 VanDerWaalsContact O-N 3.07Å; V267-G270 PolarHBondContact O-N 3.21Å; G270-G272 VanDerWaalsContact C-N 3.33Å; G270-G272 PolarHBondContact O-N 3.28Å; G270-I273 PolarHBondContact O-N 3.29Å; G270-H274 PolarHBondContact O-N 3.28Å; G270-H274 PolarHBondContact O-ND1 3.02Å
271Y98.1Very high95.1Very high4 Ų410.3 Ų10.32%0.0166%0.055CC..Hα-helixtrans-62.4-38175.6-59.6-31.6000113.4E248 V267 G268 L269 H274 A275 R309 K337 N339 W553E248-Y271 HydrophobicContact CB-CD2 4.36Å; E248-Y271 HydrophobicContact CB-CE2 4.02Å; E248-Y271 HydrophobicContact CG-CE2 4.3Å; V267-Y271 HydrophobicContact CG1-CD2 4.25Å; V267-Y271 HydrophobicContact CG1-CE1 4.39Å; V267-Y271 HydrophobicContact CG1-CE2 3.5Å; V267-Y271 VanDerWaalsContact CG1-CE2 3.5Å; V267-Y271 PolarHBondContact O-N 3.12Å; G268-Y271 PolarHBondContact O-N 3.35Å; L269-Y271 VanDerWaalsContact C-N 3.34Å; L269-Y271 PolarHBondContact O-N 3.28Å; Y271-H274 PolarHBondContact O-N 3.41Å; Y271-A275 PolarHBondContact O-N 3.48Å; Y271-R309 PolarHBondContact OH-NH2 3.16Å; Y271-K337 HydrophobicContact CD1-CB 3.96Å; Y271-K337 HydrophobicContact CD1-CD 4.38Å; Y271-K337 HydrophobicContact CD1-CG 3.86Å; Y271-K337 HydrophobicContact CE1-CB 4.05Å; Y271-K337 HydrophobicContact CE1-CG 4.45Å; Y271-K337 HydrophobicContact CG-CD 4.3Å; Y271-K337 HydrophobicContact CG-CG 4.28Å; Y271-N339 WeakPolarHBondContact OH-CB 3.31Å; Y271-W553 AromaticContact CD2-CH2 3.54Å; Y271-W553 HydrophobicContact CD2-CH2 3.54Å; Y271-W553 AromaticContact CD2-CZ3 3.63Å; Y271-W553 HydrophobicContact CD2-CZ3 3.63Å; Y271-W553 HydrophobicContact CE2-CH2 4.17Å; Y271-W553 AromaticContact CE2-CZ3 3.83Å; Y271-W553 HydrophobicContact CE2-CZ3 3.83Å; Y271-W553 AromaticContact CG-CH2 3.97Å; Y271-W553 HydrophobicContact CG-CH2 3.97Å; Y271-W553 HydrophobicContact CG-CZ3 4.11Å
272G97.6Very high94.5Very high0 Ų011.4 Ų11.40%06%0.061CC..Hα-helixtrans-64.2-38.6173.800000113I252 G268 L269 G270 A275 L276I252-G272 WeakPolarHBondContact CD1-O 3.47Å; G268-G272 PolarHBondContact O-N 3.37Å; L269-G272 PolarHBondContact O-N 3.38Å; G270-G272 VanDerWaalsContact C-N 3.33Å; G270-G272 PolarHBondContact O-N 3.28Å; G272-A275 PolarHBondContact O-N 3Å; G272-L276 WeakPolarHBondContact O-CB 3.43Å; G272-L276 PolarHBondContact O-N 3.4Å
273I97Very high93.7Very high0 Ų010.7 Ų10.70%06%0.058CC..Hα-helixtrans-63.8-43.7173.9-67.4164.8000110.6V202 W203 L206 W210 L261 L269 G270 A275 L276 V277V202-I273 HydrophobicContact CG1-CD1 3.85Å; W203-I273 HydrophobicContact CD2-CD1 3.81Å; W203-I273 HydrophobicContact CD2-CG1 4.27Å; W203-I273 HydrophobicContact CE3-CD1 4.49Å; W203-I273 HydrophobicContact CG-CD1 3.88Å; W203-I273 HydrophobicContact CH2-CG1 4.42Å; W203-I273 HydrophobicContact CZ2-CD1 4.32Å; W203-I273 HydrophobicContact CZ2-CG1 4.01Å; L206-I273 HydrophobicContact CB-CG2 4.19Å; L206-I273 HydrophobicContact CD1-CB 3.83Å; L206-I273 HydrophobicContact CD1-CD1 4.2Å; L206-I273 HydrophobicContact CD1-CG2 3.63Å; W210-I273 HydrophobicContact CZ2-CG2 4.12Å; L261-I273 HydrophobicContact CD2-CG1 3.85Å; L269-I273 HydrophobicContact CD1-CD1 4.44Å; L269-I273 HydrophobicContact CG-CD1 4.12Å; L269-I273 WeakPolarHBondContact O-CG1 3.33Å; L269-I273 PolarHBondContact O-N 3.16Å; G270-I273 PolarHBondContact O-N 3.29Å; I273-A275 PolarHBondContact O-N 3.25Å; I273-L276 PolarHBondContact O-N 2.95Å; I273-V277 HydrophobicContact CG2-CG2 4.44Å; I273-V277 WeakPolarHBondContact O-CG2 3.44Å; I273-V277 PolarHBondContact O-N 3.31Å
274H96.1Very high92.4Very high5 Ų511.4 Ų11.42%0.0236%0.061CC..Hα-helixtrans-58-47.1175.3-71.198.6000112G270 Y271 L276 V277 Q278 H335G270-H274 PolarHBondContact O-N 3.28Å; G270-H274 PolarHBondContact O-ND1 3.02Å; Y271-H274 PolarHBondContact O-N 3.41Å; H274-L276 VanDerWaalsContact C-N 3.34Å; H274-L276 PolarHBondContact O-N 3.48Å; H274-V277 WeakPolarHBondContact O-CB 3.22Å; H274-V277 PolarHBondContact O-N 2.84Å; H274-Q278 WeakPolarHBondContact O-CG 3.47Å; H274-Q278 PolarHBondContact O-N 2.93Å; H274-H335 AromaticContact CD2-ND1 3.47Å; H274-H335 PolarHBondContact CD2-ND1 3.4Å
275A96.1Very high90.9Very high5 Ų513.7 Ų13.74%0.0417%0.072CC..Hα-helixtrans-62.2-40.6177.100000112.2Y250 I252 Y271 G272 I273 Q278 M279Y250-A275 HydrophobicContact CE2-CB 4.06Å; Y250-A275 VanDerWaalsContact OH-CB 3.24Å; Y250-A275 WeakPolarHBondContact OH-CB 3.46Å; I252-A275 HydrophobicContact CD1-CB 3.94Å; Y271-A275 PolarHBondContact O-N 3.48Å; G272-A275 PolarHBondContact O-N 3Å; I273-A275 PolarHBondContact O-N 3.25Å; A275-Q278 PolarHBondContact O-N 3.48Å; A275-M279 VanDerWaalsContact O-CG 3.24Å; A275-M279 WeakPolarHBondContact O-CG 3.49Å; A275-M279 PolarHBondContact O-N 3.46Å
276L95.2Very high89.3Confident1 Ų113.1 Ų13.11%0.0058%0.076CC..Hα-helixtrans-63.2-43.3176.3-177.761.6000112W203 W210 V235 I252 I259 G272 I273 H274 Q278 M279 V280W203-L276 HydrophobicContact CH2-CD2 4.18Å; W210-L276 HydrophobicContact CH2-CD2 3.85Å; W210-L276 HydrophobicContact CH2-CG 3.91Å; W210-L276 HydrophobicContact CZ2-CD2 4.24Å; V235-L276 HydrophobicContact CG1-CD2 4.48Å; V235-L276 HydrophobicContact CG2-CD2 4.21Å; I252-L276 HydrophobicContact CD1-CB 4.41Å; I259-L276 HydrophobicContact CD1-CD1 3.87Å; I259-L276 HydrophobicContact CG2-CD1 4Å; G272-L276 WeakPolarHBondContact O-CB 3.43Å; G272-L276 PolarHBondContact O-N 3.4Å; I273-L276 PolarHBondContact O-N 2.95Å; H274-L276 VanDerWaalsContact C-N 3.34Å; H274-L276 PolarHBondContact O-N 3.48Å; L276-Q278 VanDerWaalsContact C-N 3.31Å; L276-Q278 PolarHBondContact O-N 3.17Å; L276-M279 PolarHBondContact O-N 2.99Å; L276-V280 HydrophobicContact CD1-CG2 4.36Å; L276-V280 WeakPolarHBondContact O-CG2 3.45Å; L276-V280 PolarHBondContact O-N 2.89Å
277V92.9Very high87.3Confident6 Ų613.1 Ų13.14%0.0368%0.075CC..Hα-helixtrans-57.5-45.9174.2166.70000110.5L209 W210 L213 I273 H274 V280 R281L209-V277 HydrophobicContact CB-CG1 4.05Å; L209-V277 HydrophobicContact CB-CG2 4.07Å; L209-V277 HydrophobicContact CD1-CG2 4.35Å; W210-V277 HydrophobicContact CD2-CG2 4.01Å; W210-V277 HydrophobicContact CE3-CG2 4.37Å; W210-V277 HydrophobicContact CH2-CG2 3.95Å; W210-V277 HydrophobicContact CZ2-CG2 3.53Å; W210-V277 HydrophobicContact CZ3-CG2 4.34Å; L213-V277 HydrophobicContact CD1-CG1 3.96Å; I273-V277 HydrophobicContact CG2-CG2 4.44Å; I273-V277 WeakPolarHBondContact O-CG2 3.44Å; I273-V277 PolarHBondContact O-N 3.31Å; H274-V277 WeakPolarHBondContact O-CB 3.22Å; H274-V277 PolarHBondContact O-N 2.84Å; V277-V280 PolarHBondContact O-N 3.23Å; V277-R281 WeakPolarHBondContact O-CB 3.21Å; V277-R281 PolarHBondContact O-N 3.33Å
278Q92.3Very high84.9Confident4 Ų417 Ų172%0.01910%0.098CC..Hα-helixtrans-62-45.6177.7-68.61771500111.8L160 W161 H274 A275 L276 V280 R281 L282 H335 H573L160-Q278 HydrophobicContact CD2-CB 3.92Å; W161-Q278 PolarHBondContact O-NE2 3.15Å; W161-Q278 PolarHBondContact O-OE1 3Å; W161-Q278 VanDerWaalsContact O-OE1 3.05Å; H274-Q278 WeakPolarHBondContact O-CG 3.47Å; H274-Q278 PolarHBondContact O-N 2.93Å; A275-Q278 PolarHBondContact O-N 3.48Å; L276-Q278 VanDerWaalsContact C-N 3.31Å; L276-Q278 PolarHBondContact O-N 3.17Å; Q278-V280 PolarHBondContact O-N 3.13Å; Q278-R281 PolarHBondContact O-N 3.44Å; Q278-L282 VanDerWaalsContact O-CB 3.29Å; Q278-L282 WeakPolarHBondContact O-CB 3.34Å; Q278-L282 VanDerWaalsContact O-CG 3.29Å; Q278-L282 WeakPolarHBondContact O-CG 2.94Å; Q278-L282 PolarHBondContact O-N 3.25Å; Q278-H335 WeakPolarHBondContact CG-NE2 3.4Å; Q278-H335 PolarHBondContact NE2-NE2 3.24Å; Q278-H573 PolarHBondContact OE1-CE1 3.29Å
279M89.6Confident82.4Confident0 Ų018.4 Ų18.40%011%0.113CC..Hα-helixtrans-60.2-47.1178-69.1165.15900112.1W156 L160 I252 V254 A275 L276 R281 C283 L295 L298 I300W156-M279 HydrophobicContact CH2-CG 4.27Å; W156-M279 HydrophobicContact CZ3-CB 4.45Å; W156-M279 HydrophobicContact CZ3-CG 4.17Å; L160-M279 HydrophobicContact CD1-CG 4.33Å; L160-M279 HydrophobicContact CD2-CG 3.73Å; I252-M279 HydrophobicContact CD1-SD 4.32Å; I252-M279 HydrophobicContact CG2-CE 4.37Å; I252-M279 HydrophobicContact CG2-SD 4.47Å; V254-M279 HydrophobicContact CG2-CE 3.82Å; A275-M279 VanDerWaalsContact O-CG 3.24Å; A275-M279 WeakPolarHBondContact O-CG 3.49Å; A275-M279 PolarHBondContact O-N 3.46Å; L276-M279 PolarHBondContact O-N 2.99Å; M279-R281 VanDerWaalsContact C-N 3.34Å; M279-R281 PolarHBondContact O-N 3.44Å; M279-C283 VanDerWaalsContact O-CB 3.28Å; M279-C283 WeakPolarHBondContact O-CB 3.27Å; M279-C283 PolarHBondContact O-N 3.29Å; M279-C283 PolarHBondContact O-SG 3.01Å; M279-L295 HydrophobicContact CB-CD1 4.24Å; M279-L295 HydrophobicContact CE-CD1 3.86Å; M279-L295 HydrophobicContact CE-CD2 3.71Å; M279-L295 HydrophobicContact CE-CG 4.28Å; M279-L298 HydrophobicContact CE-CD1 3.78Å; M279-L298 HydrophobicContact CE-CD2 4.14Å; M279-L298 HydrophobicContact CE-CG 4.37Å; M279-I300 HydrophobicContact CE-CD1 4.24Å; M279-I300 HydrophobicContact CG-CD1 4.4Å; M279-I300 HydrophobicContact SD-CD1 3.47Å; M279-I300 WeakPolarHBondContact SD-CD1 3.18Å
280V87.7Confident79.9Confident4 Ų422.4 Ų22.42%0.02414%0.139CC..Iπ-helixtrans-60.4-45.7177.3168.70000110.3M179 W210 L213 L276 V277 Q278 L284 L285M179-V280 HydrophobicContact CE-CG1 4.35Å; W210-V280 HydrophobicContact CZ3-CG2 4.46Å; L213-V280 HydrophobicContact CD1-CB 4.43Å; L213-V280 HydrophobicContact CD1-CG1 4.04Å; L276-V280 HydrophobicContact CD1-CG2 4.36Å; L276-V280 WeakPolarHBondContact O-CG2 3.45Å; L276-V280 PolarHBondContact O-N 2.89Å; V277-V280 PolarHBondContact O-N 3.23Å; Q278-V280 PolarHBondContact O-N 3.13Å; V280-L284 HydrophobicContact CB-CD1 4.46Å; V280-L284 HydrophobicContact CG1-CD1 4.17Å; V280-L284 HydrophobicContact CG2-CD1 4.26Å; V280-L284 WeakPolarHBondContact O-CA 3.45Å; V280-L284 VanDerWaalsContact O-CB 3.27Å; V280-L284 WeakPolarHBondContact O-CB 3.36Å; V280-L284 PolarHBondContact O-N 3.05Å; V280-L285 HydrophobicContact CG1-CD1 4.42Å; V280-L285 PolarHBondContact O-N 3.2Å
281R85.5Confident77.7Confident24 Ų2426.7 Ų26.79%0.09117%0.165CC..Iπ-helixtrans-63.9-50.1179.6-177.4165.5163-86.1-25.7112.2L213 V277 Q278 M279 G286 D572 N576L213-R281 HydrophobicContact CD1-CB 4.32Å; L213-R281 HydrophobicContact CD2-CB 3.79Å; L213-R281 HydrophobicContact CD2-CG 3.83Å; V277-R281 WeakPolarHBondContact O-CB 3.21Å; V277-R281 PolarHBondContact O-N 3.33Å; Q278-R281 PolarHBondContact O-N 3.44Å; M279-R281 VanDerWaalsContact C-N 3.34Å; M279-R281 PolarHBondContact O-N 3.44Å; R281-G286 PolarHBondContact O-N 3.03Å; R281-D572 VanDerWaalsContact CZ-O 3.22Å; R281-D572 IonicContact CZ-OD1 2.67Å; R281-D572 IonicContact CZ-OD2 2.67Å; R281-D572 PolarHBondContact NH1-O 3.13Å; R281-D572 IonicContact NH1-OD1 3.23Å; R281-D572 PolarHBondContact NH1-OD1 2.85Å; R281-D572 IonicContact NH1-OD2 2.78Å; R281-D572 PolarHBondContact NH1-OD2 2.92Å; R281-D572 PolarHBondContact NH2-O 3.48Å; R281-D572 IonicContact NH2-OD1 3.98Å; R281-D572 PolarHBondContact NH2-OD1 2.92Å; R281-D572 IonicContact NH2-OD2 2.78Å; R281-N576 VanDerWaalsContact NH2-CA 3.26Å; R281-N576 PolarHBondContact NH2-O 3.48Å
282L84.1Confident75.7Confident23 Ų2328.8 Ų28.812%0.1218%0.175CC..Iπ-helixtrans-67.2-41-177.1-73170.2000112.8W156 M159 L160 Q278 D572W156-L282 HydrophobicContact CE3-CB 4.22Å; M159-L282 HydrophobicContact CB-CD1 3.89Å; M159-L282 HydrophobicContact CB-CD2 3.84Å; L160-L282 HydrophobicContact CD2-CD1 3.86Å; L160-L282 HydrophobicContact CG-CD1 4.27Å; Q278-L282 VanDerWaalsContact O-CB 3.29Å; Q278-L282 WeakPolarHBondContact O-CB 3.34Å; Q278-L282 VanDerWaalsContact O-CG 3.29Å; Q278-L282 WeakPolarHBondContact O-CG 2.94Å; Q278-L282 PolarHBondContact O-N 3.25Å; L282-D572 VanDerWaalsContact CD2-OD2 3.23Å; L282-D572 WeakPolarHBondContact CD2-OD2 3.36Å
283C79.1Confident74.1Confident2 Ų232 Ų321%0.01420%0.201CC..Iπ-helixtrans-87.6-54.4-176.8-60.40000112.9W156 M279 L295W156-C283 WeakPolarHBondContact CH2-SG 3.49Å; W156-C283 WeakPolarHBondContact CZ2-SG 3.27Å; W156-C283 WeakPolarHBondContact CZ3-SG 3.47Å; M279-C283 VanDerWaalsContact O-CB 3.28Å; M279-C283 WeakPolarHBondContact O-CB 3.27Å; M279-C283 PolarHBondContact O-N 3.29Å; M279-C283 PolarHBondContact O-SG 3.01Å; C283-L295 HydrophobicContact CB-CD1 4.07Å; C283-L295 VanDerWaalsContact SG-CD1 3.51Å
284L70.7Confident73.3Confident15 Ų1533.6 Ų33.68%0.07921%0.213CC..Iπ-helixtrans-90.9-26.8-161.8-59.2177.2000112.8M179 V280 P290 L295M179-L284 HydrophobicContact CB-CD1 4.01Å; M179-L284 HydrophobicContact CE-CD1 4.15Å; V280-L284 HydrophobicContact CB-CD1 4.46Å; V280-L284 HydrophobicContact CG1-CD1 4.17Å; V280-L284 HydrophobicContact CG2-CD1 4.26Å; V280-L284 WeakPolarHBondContact O-CA 3.45Å; V280-L284 VanDerWaalsContact O-CB 3.27Å; V280-L284 WeakPolarHBondContact O-CB 3.36Å; V280-L284 PolarHBondContact O-N 3.05Å; L284-P290 WeakPolarHBondContact O-CB 3.31Å; L284-L295 HydrophobicContact CD2-CB 4.45Å
285L66.5Low72.7Confident59 Ų5933.4 Ų33.431%0.30921%0.212SC..Iπ-helixtrans-105.9-34.7-173.8-64.4174.8000112.6L213 V280 G289L213-L285 HydrophobicContact CB-CD1 3.71Å; L213-L285 HydrophobicContact CD1-CD1 4.34Å; L213-L285 HydrophobicContact CD2-CD1 3.9Å; L213-L285 HydrophobicContact CG-CD1 4.17Å; V280-L285 HydrophobicContact CG1-CD1 4.42Å; V280-L285 PolarHBondContact O-N 3.2Å; L285-G289 CarbonylContact O-C 3.51Å; L285-G289 WeakPolarHBondContact O-CA 3.12Å
286G62.5Low72.3Confident27 Ų2734.5 Ų34.528%0.27822%0.218SC..THydrogen-bonded Turntrans52.3-175.8-176.900000112.6R281R281-G286 PolarHBondContact O-N 3.03Å
287E55.1Low72.1Confident55 Ų5535.5 Ų35.526%0.25722%0.224SC..THydrogen-bonded Turntrans-88.9-33.8174-65.6-165.8102.100113.2S577 R578 Q579E287-S577 PolarHBondContact OE1-OG 3.33Å; E287-R578 VanDerWaalsContact CD-CB 3.41Å; E287-R578 HydrophobicContact CG-CB 4.15Å; E287-R578 VanDerWaalsContact OE1-C 3.31Å; E287-R578 VanDerWaalsContact OE1-CA 3.22Å; E287-R578 WeakPolarHBondContact OE1-CA 3.47Å; E287-R578 PolarHBondContact OE1-N 2.87Å; E287-R578 WeakPolarHBondContact OE2-CB 3.49Å; E287-R578 IonicContact OE2-CZ 3.48Å; E287-R578 IonicContact OE2-NE 3.77Å; E287-R578 PolarHBondContact OE2-NE 2.79Å; E287-R578 IonicContact OE2-NH2 3.68Å; E287-R578 PolarHBondContact OE2-NH2 3.35Å; E287-Q579 WeakPolarHBondContact OE1-CG 3.35Å; E287-Q579 PolarHBondContact OE1-N 3Å; E287-Q579 PolarHBondContact OE2-N 3.38Å
288T45Very low72.1Confident122 Ų12235.2 Ų35.275%0.74822%0.222SC*.THydrogen-bonded Turntrans-113.219.4-17554.50000112.1
289G46.1Very low72.2Confident30 Ų3039.7 Ų39.731%0.30924%0.239SC..SBendtrans111.3173-170.300000112.2L285 V291L285-G289 CarbonylContact O-C 3.51Å; L285-G289 WeakPolarHBondContact O-CA 3.12Å; G289-V291 PolarHBondContact O-N 2.97Å
290P44.8Very low72.6Confident85 Ų8539.8 Ų39.855%0.55224%0.239SC*.  trans-59113.6-174.821.7-31.5000110.6L284 Q292L284-P290 WeakPolarHBondContact O-CB 3.31Å; P290-Q292 VanDerWaalsContact C-N 3.33Å
291V50.6Low73Confident90 Ų9045 Ų4555%0.54526%0.259SS..SBendtrans-71.5-36172.3-178.90000109.6G289G289-V291 PolarHBondContact O-N 2.97Å
292Q55.2Low73.6Confident47 Ų4743.9 Ų43.922%0.2225%0.254CS..SBendtrans-132.9124.2166.6-77.6176.4-24.100107.9D154 P290 S294D154-Q292 PolarHBondContact OD1-NE2 3.02Å; P290-Q292 VanDerWaalsContact C-N 3.33Å; Q292-S294 PolarHBondContact O-N 2.75Å
293A64.6Low74.2Confident67 Ų6745 Ų4555%0.55426%0.257SS*.SBendtrans-71.111.3178.500000113.8S178S178-A293 PolarHBondContact OG-O 3.32Å
294S79.1Confident75Confident35 Ų3545.8 Ų45.825%0.24526%0.262CS..SBendtrans-159.7142.2-172.759.90000111.7A176 F177 Q292A176-S294 WeakPolarHBondContact CB-OG 3.23Å; F177-S294 CarbonylContact O-C 3.56Å; F177-S294 WeakPolarHBondContact O-CA 3.41Å; F177-S294 WeakPolarHBondContact O-CB 3.43Å; Q292-S294 PolarHBondContact O-N 2.75Å
295L85Confident76.2Confident0 Ų047.2 Ų47.20%027%0.273CS..EExtended strand (participates in β ladder)trans-83128173.7-179.272.8000108.9W156 A176 F177 V254 I259 M279 C283 L284 L298W156-L295 HydrophobicContact CH2-CD1 3.84Å; W156-L295 HydrophobicContact CZ2-CD1 3.95Å; A176-L295 CarbonylContact C-O 3.6Å; A176-L295 WeakPolarHBondContact CB-O 3.41Å; F177-L295 HydrophobicContact CB-CB 4.25Å; F177-L295 HydrophobicContact CD1-CB 4.46Å; F177-L295 PolarHBondContact N-O 3.34Å; F177-L295 PolarHBondContact O-N 3.23Å; V254-L295 HydrophobicContact CB-CD2 4.2Å; V254-L295 HydrophobicContact CG1-CB 4.49Å; V254-L295 HydrophobicContact CG1-CD2 3.57Å; V254-L295 HydrophobicContact CG1-CG 3.95Å; V254-L295 HydrophobicContact CG2-CD2 3.54Å; V254-L295 HydrophobicContact CG2-CG 4.31Å; I259-L295 HydrophobicContact CD1-CD2 4.09Å; M279-L295 HydrophobicContact CB-CD1 4.24Å; M279-L295 HydrophobicContact CE-CD1 3.86Å; M279-L295 HydrophobicContact CE-CD2 3.71Å; M279-L295 HydrophobicContact CE-CG 4.28Å; C283-L295 HydrophobicContact CB-CD1 4.07Å; C283-L295 VanDerWaalsContact SG-CD1 3.51Å; L284-L295 HydrophobicContact CD2-CB 4.45Å; L295-L298 HydrophobicContact CD1-CD2 4.24Å
296P86.2Confident77.5Confident28 Ų2844.9 Ų44.918%0.18226%0.261CS..EExtended strand (participates in β ladder)trans-64.3154.1178.424.4-31.6000111.4W156 I169 L298W156-P296 HydrophobicContact CZ2-CG 3.88Å; I169-P296 HydrophobicContact CG2-CB 4.46Å; P296-L298 HydrophobicContact CG-CD2 4.25Å; P296-L298 WeakPolarHBondContact O-CG 3.41Å; P296-L298 PolarHBondContact O-N 3.42Å
297L91Very high79.1Confident22 Ų2251.4 Ų51.412%0.11528%0.277CS..SBendtrans-65.1118.6174.4-55.4-169.3000109.1H170 S173 Q175H170-L297 HydrophobicContact CB-CB 4.27Å; H170-L297 PolarHBondContact N-O 3.42Å; S173-L297 WeakPolarHBondContact OG-CD1 3.33Å; Q175-L297 HydrophobicContact CB-CD1 4.12Å
298L93.1Very high81Confident1 Ų149.2 Ų49.21%0.00527%0.267CS..EExtended strand (participates in β ladder)trans-152.4164.5-173.66882.6000110.9W156 L167 S168 I169 V254 M279 L295 P296 I300W156-L298 HydrophobicContact CH2-CD2 3.77Å; W156-L298 HydrophobicContact CZ2-CD2 3.71Å; L167-L298 HydrophobicContact CD1-CD1 4.19Å; S168-L298 CarbonylContact O-C 3.51Å; S168-L298 VanDerWaalsContact O-CA 3.23Å; S168-L298 WeakPolarHBondContact O-CA 3.43Å; S168-L298 WeakPolarHBondContact O-CB 3.49Å; I169-L298 HydrophobicContact CG1-CB 4.23Å; V254-L298 HydrophobicContact CB-CD1 4.5Å; V254-L298 HydrophobicContact CB-CG 4.15Å; V254-L298 HydrophobicContact CG2-CD1 3.8Å; V254-L298 HydrophobicContact CG2-CG 3.85Å; V254-L298 PolarHBondContact N-O 2.69Å; V254-L298 PolarHBondContact O-N 3.48Å; M279-L298 HydrophobicContact CE-CD1 3.78Å; M279-L298 HydrophobicContact CE-CD2 4.14Å; M279-L298 HydrophobicContact CE-CG 4.37Å; L295-L298 HydrophobicContact CD1-CD2 4.24Å; P296-L298 HydrophobicContact CG-CD2 4.25Å; P296-L298 WeakPolarHBondContact O-CG 3.41Å; P296-L298 PolarHBondContact O-N 3.42Å; L298-I300 HydrophobicContact CD1-CD1 4.01Å; L298-I300 HydrophobicContact CD1-CG1 3.87Å
299R95.5Very high83.6Confident97 Ų9743.4 Ų43.437%0.36623%0.231SC..EExtended strand (participates in β ladder)trans-134.2129.9170.9-176.3173.3-178.3-174.12.1110.3S168 D251 I252 T253 R301S168-R299 PolarHBondContact N-O 2.9Å; S168-R299 PolarHBondContact O-N 2.76Å; S168-R299 PolarHBondContact OG-O 2.94Å; D251-R299 WeakPolarHBondContact OD1-CG 3.32Å; D251-R299 IonicContact OD1-NE 2.77Å; D251-R299 PolarHBondContact OD1-NE 3.35Å; D251-R299 VanDerWaalsContact OD1-NE 3.13Å; D251-R299 IonicContact OD2-CZ 3.25Å; D251-R299 VanDerWaalsContact OD2-CZ 3.23Å; D251-R299 IonicContact OD2-NE 2.87Å; D251-R299 PolarHBondContact OD2-NE 3.41Å; D251-R299 IonicContact OD2-NH2 3.18Å; D251-R299 PolarHBondContact OD2-NH2 2.89Å; I252-R299 CarbonylContact O-C 3.57Å; I252-R299 VanDerWaalsContact O-CA 3.25Å; I252-R299 WeakPolarHBondContact O-CA 3.48Å; T253-R299 WeakPolarHBondContact OG1-CD 3.49Å; T253-R299 WeakPolarHBondContact OG1-CG 3.44Å; R299-R301 HydrophobicContact CG-CG 4.43Å
300I97.1Very high86Confident2 Ų242 Ų421%0.0122%0.216CC..EExtended strand (participates in β ladder)trans-111.2119.6172.5-69.3166.4000107.5L160 P164 Q166 L167 Y250 D251 I252 M279 L298 D302L160-I300 HydrophobicContact CD1-CD1 4.15Å; P164-I300 HydrophobicContact CB-CG2 3.78Å; Q166-I300 WeakPolarHBondContact O-CA 3.47Å; L167-I300 HydrophobicContact CD1-CD1 4.18Å; L167-I300 HydrophobicContact CD1-CG1 3.52Å; Y250-I300 HydrophobicContact CE2-CG2 4.01Å; D251-I300 CarbonylContact C-O 3.56Å; D251-I300 VanDerWaalsContact CA-O 3.26Å; D251-I300 WeakPolarHBondContact CA-O 3.45Å; I252-I300 HydrophobicContact CB-CB 4.39Å; I252-I300 PolarHBondContact N-O 3.47Å; I252-I300 PolarHBondContact O-N 3.45Å; M279-I300 HydrophobicContact CE-CD1 4.24Å; M279-I300 HydrophobicContact CG-CD1 4.4Å; M279-I300 HydrophobicContact SD-CD1 3.47Å; M279-I300 WeakPolarHBondContact SD-CD1 3.18Å; L298-I300 HydrophobicContact CD1-CD1 4.01Å; L298-I300 HydrophobicContact CD1-CG1 3.87Å; I300-D302 HydrophobicContact CG2-CB 3.95Å
301R97Very high88.5Confident114 Ų11438 Ų3843%0.4319%0.191SC..EExtended strand (participates in β ladder)trans-110.7121.9165.2-66-168.3-61-175.3-3.9107.6Q166 D251 R299 W303Q166-R301 HydrophobicContact CB-CB 4.26Å; Q166-R301 WeakPolarHBondContact CB-O 3.44Å; Q166-R301 PolarHBondContact N-O 3.46Å; Q166-R301 VanDerWaalsContact N-O 3.09Å; Q166-R301 PolarHBondContact O-N 3.09Å; D251-R301 HydrophobicContact CB-CG 4.3Å; D251-R301 WeakPolarHBondContact OD2-CG 3.21Å; R299-R301 HydrophobicContact CG-CG 4.43Å; R301-W303 HydrophobicContact CB-CZ3 4.22Å
302D97.7Very high90.8Very high1 Ų133.8 Ų33.81%0.00517%0.165CC..EExtended strand (participates in β ladder)trans-141.3152.5-169.5-155.715.6000112.3Q165 S249 Y250 I300 K337 W553Q165-D302 WeakPolarHBondContact CG-OD1 3.4Å; Q165-D302 PolarHBondContact N-OD1 3.08Å; S249-D302 WeakPolarHBondContact CA-O 3.4Å; Y250-D302 HydrophobicContact CD1-CB 4.4Å; Y250-D302 HydrophobicContact CD2-CB 4.44Å; Y250-D302 HydrophobicContact CE1-CB 3.79Å; Y250-D302 HydrophobicContact CE2-CB 3.83Å; Y250-D302 VanDerWaalsContact CZ-CB 3.48Å; Y250-D302 PolarHBondContact N-O 3.42Å; Y250-D302 PolarHBondContact O-N 2.91Å; Y250-D302 PolarHBondContact OH-OD2 3.23Å; I300-D302 HydrophobicContact CG2-CB 3.95Å; D302-K337 IonicContact OD2-NZ 2.8Å; D302-K337 PolarHBondContact OD2-NZ 2.93Å; D302-W553 HydrophobicContact CB-CZ2 4.42Å; D302-W553 PolarHBondContact OD1-NE1 3.25Å; D302-W553 WeakPolarHBondContact OD2-CZ2 3.49Å; D302-W553 PolarHBondContact OD2-NE1 3.37Å
303W96.9Very high92.7Very high47 Ų4731.5 Ų31.518%0.17815%0.154CC..  trans-164.1155.5-178.558.478.4000109.1Q165 Q166 S249 R301Q165-W303 HydrophobicContact CB-CD2 4.08Å; Q165-W303 HydrophobicContact CB-CE3 4.26Å; Q165-W303 HydrophobicContact CB-CH2 3.9Å; Q165-W303 HydrophobicContact CB-CZ2 3.66Å; Q165-W303 HydrophobicContact CB-CZ3 4.17Å; Q165-W303 HydrophobicContact CG-CD2 3.9Å; Q165-W303 HydrophobicContact CG-CE3 4.49Å; Q165-W303 HydrophobicContact CG-CG 4.12Å; Q165-W303 HydrophobicContact CG-CZ2 4.05Å; Q165-W303 WeakPolarHBondContact CG-O 3.21Å; Q165-W303 PolarHBondContact NE2-O 2.69Å; Q166-W303 HydrophobicContact CG-CH2 3.76Å; Q166-W303 HydrophobicContact CG-CZ3 4.28Å; S249-W303 WeakPolarHBondContact OG-CB 3.36Å; R301-W303 HydrophobicContact CB-CZ3 4.22Å
304P96.6Very high94.1Very high18 Ų1828.6 Ų28.612%0.11713%0.129CC..  trans-73.1139.6175.228.2-33.3000112.3E248 Q306 W553E248-P304 HydrophobicContact CB-CG 4Å; P304-Q306 WeakPolarHBondContact CB-O 3.44Å; P304-W553 HydrophobicContact CB-CD2 4.32Å; P304-W553 HydrophobicContact CB-CE3 3.75Å; P304-W553 HydrophobicContact CB-CH2 4.31Å; P304-W553 HydrophobicContact CB-CZ3 3.74Å; P304-W553 HydrophobicContact CG-CH2 4.42Å; P304-W553 HydrophobicContact CG-CZ3 4.15Å
305S94.9Very high94.8Very high45 Ų4527.5 Ų27.532%0.31512%0.12SC..SBendtrans-71.7-37.9169.4-56.40000111Q165 W553 N554 C555Q165-S305 PolarHBondContact NE2-OG 3.28Å; S305-W553 VanDerWaalsContact CB-O 3.31Å; S305-W553 WeakPolarHBondContact CB-O 3.39Å; S305-W553 PolarHBondContact N-O 3.01Å; S305-W553 PolarHBondContact OG-O 2.84Å; S305-N554 WeakPolarHBondContact OG-CA 3.43Å; S305-C555 PolarHBondContact OG-N 2.75Å
306Q94.7Very high94.9Very high10 Ų1029.3 Ų29.35%0.04713%0.133CC..SBendtrans-116.7137-179.2-70.3-177.3-20.900111P304 I308 R309 T524 A552P304-Q306 WeakPolarHBondContact CB-O 3.44Å; Q306-I308 VanDerWaalsContact C-N 3.35Å; Q306-R309 PolarHBondContact O-NH1 3.31Å; Q306-T524 VanDerWaalsContact CD-OG1 3.29Å; Q306-T524 PolarHBondContact NE2-OG1 3.02Å; Q306-T524 VanDerWaalsContact NE2-OG1 3.17Å; Q306-T524 VanDerWaalsContact OE1-CB 3.3Å; Q306-T524 PolarHBondContact OE1-OG1 3.41Å; Q306-A552 HydrophobicContact CB-CB 4.46Å; Q306-A552 WeakPolarHBondContact CB-O 3.29Å; Q306-A552 PolarHBondContact N-O 3.47Å; Q306-A552 VanDerWaalsContact OE1-CA 3.27Å
307R94.2Very high94.9Very high164 Ų16429.3 Ų29.362%0.61914%0.138SC*.SBendtrans-69-34.7179.5-174.8175.1176.1-176.3-4.4112.1R309 N339 L522R307-R309 PolarHBondContact O-NH1 3.21Å; R307-N339 PolarHBondContact O-ND2 2.99Å; R307-L522 PolarHBondContact N-O 3.43Å
308I97Very high94.7Very high8 Ų829.6 Ų29.64%0.04114%0.142CC..EExtended strand (participates in β ladder)trans-109.2122.9-178.5-61171.8000109.4Q306 A310 F437 V462 L522 G523 T524Q306-I308 VanDerWaalsContact C-N 3.35Å; I308-A310 HydrophobicContact CG2-CB 4.05Å; I308-F437 HydrophobicContact CD1-CE1 3.81Å; I308-F437 HydrophobicContact CD1-CZ 4Å; I308-F437 HydrophobicContact CG2-CE1 4.08Å; I308-F437 HydrophobicContact CG2-CZ 4.26Å; I308-V462 HydrophobicContact CD1-CG1 4.42Å; I308-L522 HydrophobicContact CD1-CB 4Å; I308-L522 HydrophobicContact CD1-CD1 4.09Å; I308-L522 HydrophobicContact CG1-CB 4.49Å; I308-L522 PolarHBondContact N-O 3.33Å; I308-G523 CarbonylContact O-C 3.53Å; I308-G523 WeakPolarHBondContact O-CA 3.49Å; I308-T524 PolarHBondContact O-N 3.43Å
309R97.7Very high94.6Very high0 Ų030 Ų300%014%0.143CC..EExtended strand (participates in β ladder)trans-133.185.8-179.7-58.6176.1-62.8-74.82.7106.8E248 Y271 Q306 R307 K337 A338 N339 H340 L549 A552E248-R309 IonicContact OE2-CZ 3.9Å; E248-R309 IonicContact OE2-NH1 3.9Å; E248-R309 PolarHBondContact OE2-NH1 2.85Å; E248-R309 IonicContact OE2-NH2 3.81Å; E248-R309 PolarHBondContact OE2-NH2 3.43Å; Y271-R309 PolarHBondContact OH-NH2 3.16Å; Q306-R309 PolarHBondContact O-NH1 3.31Å; R307-R309 PolarHBondContact O-NH1 3.21Å; R309-K337 PolarHBondContact NE-O 3.31Å; R309-A338 WeakPolarHBondContact O-CA 3.39Å; R309-N339 PolarHBondContact N-OD1 3.26Å; R309-N339 PolarHBondContact NH2-ND2 3.37Å; R309-N339 PolarHBondContact O-N 3.37Å; R309-N339 PolarHBondContact O-OD1 2.99Å; R309-H340 PolarHBondContact O-N 3.43Å; R309-L549 HydrophobicContact CB-CD2 4.18Å; R309-A552 HydrophobicContact CB-CB 4.4Å; R309-A552 HydrophobicContact CG-CB 3.78Å
310A98Very high94.6Very high0 Ų025.7 Ų25.70%013%0.128CC..EExtended strand (participates in β ladder)trans-111.4145.5-163.200000112.6I308 H340 L342 T524 V525 I526I308-A310 HydrophobicContact CG2-CB 4.05Å; A310-H340 VanDerWaalsContact CA-O 3.29Å; A310-H340 WeakPolarHBondContact CA-O 3.4Å; A310-H340 HydrophobicContact CB-CB 3.7Å; A310-L342 HydrophobicContact CB-CD1 4.01Å; A310-T524 PolarHBondContact N-O 2.98Å; A310-V525 HydrophobicContact CB-CB 4.26Å; A310-V525 HydrophobicContact CB-CG1 4Å; A310-V525 HydrophobicContact CB-CG2 3.98Å; A310-V525 WeakPolarHBondContact O-CA 3.22Å; A310-I526 WeakPolarHBondContact O-CG2 3.45Å; A310-I526 PolarHBondContact O-N 2.94Å
311L97.4Very high94.5Very high2 Ų225.8 Ų25.81%0.0113%0.128CC..EExtended strand (participates in β ladder)trans-109.6132165.1172.566.7000108.7L313 I329 M333 H340 L341 L342 I526L311-L313 HydrophobicContact CD1-CD2 4.33Å; L311-L313 HydrophobicContact CD2-CD2 3.97Å; L311-L313 HydrophobicContact CD2-CG 4.35Å; L311-L313 HydrophobicContact CG-CD2 4.11Å; L311-L313 HydrophobicContact CG-CG 4.4Å; L311-I329 HydrophobicContact CD2-CG2 3.6Å; L311-M333 HydrophobicContact CD2-CE 4.48Å; L311-M333 HydrophobicContact CD2-CG 3.7Å; L311-M333 HydrophobicContact CD2-SD 4.29Å; L311-H340 PolarHBondContact N-O 3.33Å; L311-L341 HydrophobicContact CB-CD1 4.32Å; L311-L341 HydrophobicContact CD2-CD1 4.06Å; L311-L341 HydrophobicContact CG-CD1 4.24Å; L311-L341 CarbonylContact O-C 3.52Å; L311-L341 WeakPolarHBondContact O-CA 3.19Å; L311-L342 PolarHBondContact O-N 2.66Å; L311-I526 WeakPolarHBondContact CA-O 3.46Å; L311-I526 HydrophobicContact CB-CG2 4.35Å; L311-I526 HydrophobicContact CD1-CG2 3.84Å
312L97.4Very high94.3Very high1 Ų122.8 Ų22.81%0.00512%0.12CC..EExtended strand (participates in β ladder)trans-107.8123.6170.6-177.9154.8000109.9D314 L342 R344 V525 I526 C527 D528 Y529L312-D314 HydrophobicContact CD2-CB 4.17Å; L312-L342 CarbonylContact C-O 3.59Å; L312-L342 WeakPolarHBondContact CA-O 3.3Å; L312-L342 HydrophobicContact CB-CB 3.93Å; L312-L342 HydrophobicContact CD1-CB 4.14Å; L312-L342 HydrophobicContact CD1-CD2 4.04Å; L312-L342 HydrophobicContact CG-CB 3.95Å; L312-R344 HydrophobicContact CD2-CB 4.23Å; L312-R344 HydrophobicContact CG-CB 4.5Å; L312-V525 HydrophobicContact CB-CG1 3.96Å; L312-I526 PolarHBondContact N-O 3.47Å; L312-C527 HydrophobicContact CB-CB 4.32Å; L312-C527 HydrophobicContact CD2-CB 4.26Å; L312-D528 PolarHBondContact O-N 2.8Å; L312-Y529 HydrophobicContact CD2-CD1 4.4Å; L312-Y529 HydrophobicContact CD2-CE1 4.02Å
313L95.7Very high94.1Very high0 Ų023.8 Ų23.80%013%0.126CC..EExtended strand (participates in β ladder)trans-103.5125.9170.9-60.3-178.1000109.2L311 F315 Y321 I326 I329 L341 L342 R344 D528L311-L313 HydrophobicContact CD1-CD2 4.33Å; L311-L313 HydrophobicContact CD2-CD2 3.97Å; L311-L313 HydrophobicContact CD2-CG 4.35Å; L311-L313 HydrophobicContact CG-CD2 4.11Å; L311-L313 HydrophobicContact CG-CG 4.4Å; L313-F315 HydrophobicContact CB-CE1 4.17Å; L313-F315 HydrophobicContact CB-CZ 4.47Å; L313-Y321 HydrophobicContact CD1-CD2 4.26Å; L313-Y321 HydrophobicContact CD2-CE2 4.33Å; L313-I326 HydrophobicContact CD1-CG2 4.41Å; L313-I329 HydrophobicContact CD1-CD1 4.3Å; L313-I329 HydrophobicContact CD1-CG2 4.47Å; L313-L341 HydrophobicContact CD1-CD1 4.02Å; L313-L341 HydrophobicContact CG-CD1 4.13Å; L313-L342 PolarHBondContact N-O 3.3Å; L313-R344 PolarHBondContact O-N 2.99Å; L313-D528 HydrophobicContact CD2-CB 4.28Å
314D93.8Very high93.9Very high5 Ų527.4 Ų27.43%0.02715%0.145CC..EExtended strand (participates in β ladder)trans-102.6115.9-175.6-173.638.1000112.4L312 S316 R344 D528 Y529 S530L312-D314 HydrophobicContact CD2-CB 4.17Å; D314-S316 PolarHBondContact OD1-OG 3.26Å; D314-S316 VanDerWaalsContact OD1-OG 3.13Å; D314-S316 PolarHBondContact OD2-OG 3.11Å; D314-R344 WeakPolarHBondContact OD1-CD 3.31Å; D314-R344 IonicContact OD1-CZ 3.88Å; D314-R344 IonicContact OD1-NH1 3.35Å; D314-R344 PolarHBondContact OD1-NH1 3.39Å; D314-R344 IonicContact OD2-NH1 3.79Å; D314-D528 WeakPolarHBondContact CB-O 3.37Å; D314-D528 PolarHBondContact N-O 2.78Å; D314-Y529 HydrophobicContact CB-CD1 3.99Å; D314-S530 PolarHBondContact OD2-N 3.18Å
315F93.4Very high93.8Very high12 Ų1226.8 Ų26.85%0.05314%0.141CC..  trans-108.922.9179.2-63-13.9000112.1L313 G317 R319 V320 Y321 I326 I343 R344 F345 F357L313-F315 HydrophobicContact CB-CE1 4.17Å; L313-F315 HydrophobicContact CB-CZ 4.47Å; F315-G317 VanDerWaalsContact C-N 3.32Å; F315-R319 WeakPolarHBondContact CD1-O 3.31Å; F315-V320 HydrophobicContact CB-CG1 4.39Å; F315-V320 HydrophobicContact CB-CG2 4.1Å; F315-V320 HydrophobicContact CD1-CG1 4.46Å; F315-V320 HydrophobicContact CD2-CG1 3.86Å; F315-V320 HydrophobicContact CE2-CG1 4.21Å; F315-V320 HydrophobicContact CG-CB 4.47Å; F315-V320 HydrophobicContact CG-CG1 4.01Å; F315-V320 HydrophobicContact CG-CG2 4.41Å; F315-Y321 AromaticContact CE1-CD2 3.55Å; F315-Y321 HydrophobicContact CE1-CD2 3.55Å; F315-Y321 HydrophobicContact CE1-CE2 4.18Å; F315-Y321 HydrophobicContact CE1-CG 4.16Å; F315-Y321 AromaticContact CZ-CD2 3.91Å; F315-Y321 HydrophobicContact CZ-CD2 3.91Å; F315-Y321 HydrophobicContact CZ-CG 4.37Å; F315-I326 HydrophobicContact CE2-CD1 3.88Å; F315-I326 HydrophobicContact CZ-CD1 3.8Å; F315-I326 HydrophobicContact CZ-CG1 4.18Å; F315-I343 HydrophobicContact CD2-CG2 3.45Å; F315-I343 VanDerWaalsContact CD2-CG2 3.45Å; F315-I343 HydrophobicContact CE2-CG2 3.39Å; F315-I343 HydrophobicContact CG-CG2 4.3Å; F315-I343 HydrophobicContact CZ-CG2 4.17Å; F315-R344 WeakPolarHBondContact CA-O 3.35Å; F315-R344 WeakPolarHBondContact CB-O 3.32Å; F315-R344 PolarHBondContact N-O 3.45Å; F315-F345 HydrophobicContact CB-CD1 4.27Å; F315-F345 HydrophobicContact CB-CE1 4.27Å; F315-F345 AromaticContact CD2-CE1 3.77Å; F315-F345 HydrophobicContact CD2-CE1 3.77Å; F315-F345 AromaticContact CD2-CZ 3.96Å; F315-F345 HydrophobicContact CD2-CZ 3.96Å; F315-F357 AromaticContact CD2-CE2 3.9Å; F315-F357 HydrophobicContact CD2-CE2 3.9Å; F315-F357 HydrophobicContact CD2-CZ 4.32Å; F315-F357 AromaticContact CE2-CE2 3.69Å; F315-F357 HydrophobicContact CE2-CE2 3.69Å; F315-F357 AromaticContact CE2-CZ 3.8Å; F315-F357 HydrophobicContact CE2-CZ 3.8Å
316S88.2Confident93.8Very high39 Ų3924.7 Ų24.727%0.27313%0.126SC..SBendtrans-75.6-20.5172.266.70000113.7D314 R344 E346D314-S316 PolarHBondContact OD1-OG 3.26Å; D314-S316 VanDerWaalsContact OD1-OG 3.13Å; D314-S316 PolarHBondContact OD2-OG 3.11Å; S316-R344 VanDerWaalsContact CB-NH1 3.35Å; S316-R344 PolarHBondContact OG-NH1 3.41Å; S316-R344 VanDerWaalsContact OG-NH1 3.13Å; S316-E346 WeakPolarHBondContact CB-OE2 3.41Å
317G85.8Confident93.8Very high27 Ų2724.8 Ų24.828%0.27813%0.13SC..SBendtrans-93.8-159.6176.900000114.1F315 R319F315-G317 VanDerWaalsContact C-N 3.32Å; G317-R319 VanDerWaalsContact C-N 3.34Å
318C86.7Confident93.7Very high29 Ų2920.2 Ų20.220%0.19612%0.115CC..SBendtrans-76.2-27.6177.2-44.70000111.6V320 E534 W741 T749 D752 A753C318-V320 PolarHBondContact O-N 3.39Å; C318-E534 VanDerWaalsContact CB-CD 3.45Å; C318-E534 HydrophobicContact CB-CG 3.88Å; C318-E534 WeakPolarHBondContact CB-OE1 3.21Å; C318-E534 PolarHBondContact N-OE1 3.32Å; C318-E534 PolarHBondContact SG-OE1 3.01Å; C318-W741 HydrophobicContact CB-CH2 4.28Å; C318-W741 HydrophobicContact CB-CZ2 4.27Å; C318-W741 WeakPolarHBondContact O-CZ2 3.35Å; C318-T749 WeakPolarHBondContact O-CB 3.48Å; C318-T749 WeakPolarHBondContact O-CG2 3.34Å; C318-T749 PolarHBondContact O-OG1 3.18Å; C318-D752 HydrophobicContact CB-CB 4.32Å; C318-A753 HydrophobicContact CB-CB 4.29Å
319R91.9Very high93.5Very high8 Ų819.9 Ų19.93%0.0311%0.114CC..  trans-70.395.9179.3-168.3175.372.4171.65.6111.6F315 G317 Y321 D528 Y529 E534 V536 W741F315-R319 WeakPolarHBondContact CD1-O 3.31Å; G317-R319 VanDerWaalsContact C-N 3.34Å; R319-Y321 WeakPolarHBondContact CD-OH 3.03Å; R319-Y321 HydrophobicContact CG-CE1 3.96Å; R319-Y321 PolarHBondContact NE-OH 3.35Å; R319-D528 IonicContact CZ-OD1 2.81Å; R319-D528 IonicContact NH1-OD1 3.56Å; R319-D528 PolarHBondContact NH1-OD1 2.87Å; R319-D528 PolarHBondContact NH2-O 2.77Å; R319-D528 VanDerWaalsContact NH2-O 3.07Å; R319-D528 IonicContact NH2-OD1 3.33Å; R319-D528 PolarHBondContact NH2-OD1 2.87Å; R319-D528 IonicContact NH2-OD2 2.89Å; R319-Y529 PolarHBondContact NH2-O 3.28Å; R319-E534 WeakPolarHBondContact CB-OE2 3.35Å; R319-E534 PolarHBondContact N-OE2 3.42Å; R319-V536 PolarHBondContact NH1-O 3.4Å; R319-W741 HydrophobicContact CB-CH2 3.87Å; R319-W741 HydrophobicContact CB-CZ3 4.48Å; R319-W741 HydrophobicContact CG-CH2 4.32Å
320V93.8Very high93.4Very high8 Ų820 Ų205%0.04811%0.114CC..  trans-122.2115.1172.2-1730000108.7F315 C318 P356 F357 N745 L746 T749F315-V320 HydrophobicContact CB-CG1 4.39Å; F315-V320 HydrophobicContact CB-CG2 4.1Å; F315-V320 HydrophobicContact CD1-CG1 4.46Å; F315-V320 HydrophobicContact CD2-CG1 3.86Å; F315-V320 HydrophobicContact CE2-CG1 4.21Å; F315-V320 HydrophobicContact CG-CB 4.47Å; F315-V320 HydrophobicContact CG-CG1 4.01Å; F315-V320 HydrophobicContact CG-CG2 4.41Å; C318-V320 PolarHBondContact O-N 3.39Å; V320-P356 HydrophobicContact CG1-CB 4.15Å; V320-P356 HydrophobicContact CG1-CG 3.92Å; V320-F357 HydrophobicContact CG1-CE2 4.13Å; V320-F357 HydrophobicContact CG1-CZ 3.8Å; V320-N745 CarbonylContact O-C 2.96Å; V320-N745 VanDerWaalsContact O-CA 3.25Å; V320-N745 WeakPolarHBondContact O-CA 3.43Å; V320-N745 WeakPolarHBondContact O-CB 3.44Å; V320-L746 HydrophobicContact CB-CD1 3.98Å; V320-L746 HydrophobicContact CG1-CD1 3.49Å; V320-L746 VanDerWaalsContact CG1-CD1 3.49Å; V320-L746 HydrophobicContact CG1-CG 4.35Å; V320-L746 PolarHBondContact O-N 3.25Å; V320-T749 HydrophobicContact CB-CG2 4.37Å; V320-T749 HydrophobicContact CG2-CG2 4.21Å
321Y95Very high93.2Very high3 Ų323.2 Ų23.21%0.01213%0.134CC..BIsolated β-bridgetrans-73.3149-176-64.2-50.8000112.8L313 F315 R319 T325 I329 F357 H538 R744 N745L313-Y321 HydrophobicContact CD1-CD2 4.26Å; L313-Y321 HydrophobicContact CD2-CE2 4.33Å; F315-Y321 AromaticContact CE1-CD2 3.55Å; F315-Y321 HydrophobicContact CE1-CD2 3.55Å; F315-Y321 HydrophobicContact CE1-CE2 4.18Å; F315-Y321 HydrophobicContact CE1-CG 4.16Å; F315-Y321 AromaticContact CZ-CD2 3.91Å; F315-Y321 HydrophobicContact CZ-CD2 3.91Å; F315-Y321 HydrophobicContact CZ-CG 4.37Å; R319-Y321 WeakPolarHBondContact CD-OH 3.03Å; R319-Y321 HydrophobicContact CG-CE1 3.96Å; R319-Y321 PolarHBondContact NE-OH 3.35Å; Y321-T325 HydrophobicContact CD1-CG2 3.73Å; Y321-T325 HydrophobicContact CE1-CG2 4.47Å; Y321-T325 HydrophobicContact CG-CG2 3.88Å; Y321-I329 HydrophobicContact CD2-CD1 3.9Å; Y321-I329 HydrophobicContact CE2-CD1 3.92Å; Y321-I329 HydrophobicContact CG-CD1 4.47Å; Y321-F357 WeakPolarHBondContact O-CE1 3.49Å; Y321-F357 VanDerWaalsContact O-CZ 3.24Å; Y321-F357 WeakPolarHBondContact O-CZ 3.38Å; Y321-H538 HydrophobicContact CE1-CB 4.38Å; Y321-H538 WeakPolarHBondContact OH-CB 3.4Å; Y321-R744 WeakPolarHBondContact CA-O 3.35Å; Y321-R744 HydrophobicContact CD1-CB 4.33Å; Y321-N745 WeakPolarHBondContact CD1-OD1 3.24Å; Y321-N745 WeakPolarHBondContact CE1-OD1 2.92Å
322M94.6Very high93Very high52 Ų5224.9 Ų24.926%0.25614%0.14SC..  trans-64.1147.7165.6-66.1-65.5-71.600110.4E324 T325 I326 R744 L746M322-E324 WeakPolarHBondContact CB-OE2 3.49Å; M322-E324 PolarHBondContact O-N 3.16Å; M322-E324 VanDerWaalsContact O-N 3.14Å; M322-T325 WeakPolarHBondContact O-CA 3.31Å; M322-T325 WeakPolarHBondContact O-CB 3.48Å; M322-T325 PolarHBondContact O-N 3.3Å; M322-I326 PolarHBondContact O-N 3.04Å; M322-R744 PolarHBondContact N-O 3.17Å; M322-L746 HydrophobicContact SD-CB 4.44Å; M322-L746 HydrophobicContact SD-CD2 3.35Å; M322-L746 WeakPolarHBondContact SD-CD2 3.45Å; M322-L746 HydrophobicContact SD-CG 4Å
323P92.7Very high92.9Very high21 Ų2125 Ų2514%0.13614%0.141CC..Hα-helixtrans-53.4-35.8177.6-25.534.4000113.5I326 G327 F357 K361P323-I326 PolarHBondContact O-N 3.08Å; P323-G327 PolarHBondContact O-N 3.49Å; P323-F357 HydrophobicContact CG-CD1 4.04Å; P323-F357 HydrophobicContact CG-CE1 4.01Å; P323-K361 HydrophobicContact CG-CB 4.32Å; P323-K361 HydrophobicContact CG-CD 4.14Å
324E91.9Very high92.9Very high123 Ų12325.1 Ų25.158%0.57514%0.142SC*.Hα-helixtrans-64.7-40.5176.9-60.473.3-158.500111.5M322 G327 Q328M322-E324 WeakPolarHBondContact CB-OE2 3.49Å; M322-E324 PolarHBondContact O-N 3.16Å; M322-E324 VanDerWaalsContact O-N 3.14Å; E324-G327 PolarHBondContact O-N 2.73Å; E324-Q328 WeakPolarHBondContact O-CG 3.43Å; E324-Q328 PolarHBondContact O-N 2.84Å
325T94.6Very high92.9Very high6 Ų625.5 Ų25.54%0.03714%0.143CC..Hα-helixtrans-66.2-42.8175.8-66.90000110.5Y321 M322 G327 Q328 I329 R744Y321-T325 HydrophobicContact CD1-CG2 3.73Å; Y321-T325 HydrophobicContact CE1-CG2 4.47Å; Y321-T325 HydrophobicContact CG-CG2 3.88Å; M322-T325 WeakPolarHBondContact O-CA 3.31Å; M322-T325 WeakPolarHBondContact O-CB 3.48Å; M322-T325 PolarHBondContact O-N 3.3Å; T325-G327 VanDerWaalsContact C-N 3.3Å; T325-G327 PolarHBondContact O-N 3.14Å; T325-Q328 PolarHBondContact O-N 3.28Å; T325-I329 HydrophobicContact CG2-CD1 4.06Å; T325-I329 VanDerWaalsContact O-CG1 3.29Å; T325-I329 WeakPolarHBondContact O-CG1 3.4Å; T325-I329 PolarHBondContact O-N 2.91Å; T325-R744 WeakPolarHBondContact CB-O 3.39Å; T325-R744 HydrophobicContact CG2-CB 4.31Å; T325-R744 WeakPolarHBondContact OG1-CA 3.29Å; T325-R744 PolarHBondContact OG1-O 3.25Å; T325-R744 VanDerWaalsContact OG1-O 3.11Å
326I95.8Very high93Very high1 Ų125 Ų251%0.00514%0.141CC..Hα-helixtrans-59.1-45.5174.2-56.6171.1000109.9L313 F315 M322 P323 Q328 I329 V330 L341 I343 F357 L365L313-I326 HydrophobicContact CD1-CG2 4.41Å; F315-I326 HydrophobicContact CE2-CD1 3.88Å; F315-I326 HydrophobicContact CZ-CD1 3.8Å; F315-I326 HydrophobicContact CZ-CG1 4.18Å; M322-I326 PolarHBondContact O-N 3.04Å; P323-I326 PolarHBondContact O-N 3.08Å; I326-Q328 VanDerWaalsContact C-N 3.33Å; I326-Q328 PolarHBondContact O-N 3.44Å; I326-I329 WeakPolarHBondContact O-CB 3.43Å; I326-I329 PolarHBondContact O-N 3.03Å; I326-I329 VanDerWaalsContact O-N 3.14Å; I326-V330 HydrophobicContact CG2-CG2 4.21Å; I326-V330 VanDerWaalsContact O-CG2 3.3Å; I326-V330 WeakPolarHBondContact O-CG2 3.46Å; I326-V330 PolarHBondContact O-N 3.47Å; I326-L341 HydrophobicContact CG2-CD2 3.92Å; I326-I343 HydrophobicContact CD1-CD1 4.4Å; I326-I343 HydrophobicContact CG2-CD1 4.37Å; I326-F357 HydrophobicContact CD1-CZ 4.05Å; I326-L365 HydrophobicContact CB-CD1 4.19Å; I326-L365 HydrophobicContact CD1-CD2 4.17Å; I326-L365 HydrophobicContact CG2-CD1 3.67Å; I326-L365 HydrophobicContact CG2-CD2 4.07Å
327G93.5Very high93.5Very high12 Ų1223.2 Ų23.212%0.12413%0.128CC..Hα-helixtrans-55.9-44.9175.900000112.9P323 E324 T325 I329 V330 V331P323-G327 PolarHBondContact O-N 3.49Å; E324-G327 PolarHBondContact O-N 2.73Å; T325-G327 VanDerWaalsContact C-N 3.3Å; T325-G327 PolarHBondContact O-N 3.14Å; G327-I329 PolarHBondContact O-N 3.25Å; G327-V330 PolarHBondContact O-N 2.92Å; G327-V331 VanDerWaalsContact O-CG2 3.29Å; G327-V331 WeakPolarHBondContact O-CG2 3.42Å; G327-V331 PolarHBondContact O-N 3.25Å
328Q91.9Very high94Very high68 Ų6822.1 Ų22.132%0.31812%0.116SC..Hα-helixtrans-63.2-40.9175.8-69.4177.1-14.100112.8E324 T325 I326 R332 E670E324-Q328 WeakPolarHBondContact O-CG 3.43Å; E324-Q328 PolarHBondContact O-N 2.84Å; T325-Q328 PolarHBondContact O-N 3.28Å; I326-Q328 VanDerWaalsContact C-N 3.33Å; I326-Q328 PolarHBondContact O-N 3.44Å; Q328-R332 WeakPolarHBondContact O-CG 3.45Å; Q328-R332 PolarHBondContact O-N 2.97Å; Q328-E670 PolarHBondContact NE2-OE1 3.17Å; Q328-E670 PolarHBondContact OE1-OE1 3.28Å; Q328-E670 PolarHBondContact OE1-OE2 3.39Å
329I94.6Very high94.5Very high1 Ų121.2 Ų21.21%0.00511%0.109CC..Hα-helixtrans-61.7-50.3176.1-65.7170.9000109.5L311 L313 Y321 T325 I326 G327 V331 R332 M333 H538L311-I329 HydrophobicContact CD2-CG2 3.6Å; L313-I329 HydrophobicContact CD1-CD1 4.3Å; L313-I329 HydrophobicContact CD1-CG2 4.47Å; Y321-I329 HydrophobicContact CD2-CD1 3.9Å; Y321-I329 HydrophobicContact CE2-CD1 3.92Å; Y321-I329 HydrophobicContact CG-CD1 4.47Å; T325-I329 HydrophobicContact CG2-CD1 4.06Å; T325-I329 VanDerWaalsContact O-CG1 3.29Å; T325-I329 WeakPolarHBondContact O-CG1 3.4Å; T325-I329 PolarHBondContact O-N 2.91Å; I326-I329 WeakPolarHBondContact O-CB 3.43Å; I326-I329 PolarHBondContact O-N 3.03Å; I326-I329 VanDerWaalsContact O-N 3.14Å; G327-I329 PolarHBondContact O-N 3.25Å; I329-V331 VanDerWaalsContact C-N 3.32Å; I329-V331 PolarHBondContact O-N 3.48Å; I329-R332 PolarHBondContact O-N 3.13Å; I329-R332 VanDerWaalsContact O-N 3.13Å; I329-M333 HydrophobicContact CG2-CE 4.44Å; I329-M333 HydrophobicContact CG2-CG 4.13Å; I329-M333 WeakPolarHBondContact O-CG 3.42Å; I329-M333 PolarHBondContact O-N 2.88Å; I329-H538 WeakPolarHBondContact CG1-NE2 3.42Å
330V95.4Very high94.8Very high2 Ų221.7 Ų21.71%0.01211%0.112CC..Hα-helixtrans-59.8-41.9-179.2176.60000111.6I326 G327 R332 M333 A334 L341 L372 V374I326-V330 HydrophobicContact CG2-CG2 4.21Å; I326-V330 VanDerWaalsContact O-CG2 3.3Å; I326-V330 WeakPolarHBondContact O-CG2 3.46Å; I326-V330 PolarHBondContact O-N 3.47Å; G327-V330 PolarHBondContact O-N 2.92Å; V330-R332 PolarHBondContact O-N 3.42Å; V330-M333 PolarHBondContact O-N 3.24Å; V330-A334 WeakPolarHBondContact O-CB 3.32Å; V330-A334 PolarHBondContact O-N 3.01Å; V330-L341 HydrophobicContact CG2-CD1 4.2Å; V330-L341 HydrophobicContact CG2-CD2 3.37Å; V330-L341 HydrophobicContact CG2-CG 4.25Å; V330-L372 HydrophobicContact CG1-CD1 3.83Å; V330-V374 HydrophobicContact CG1-CB 4.16Å; V330-V374 HydrophobicContact CG1-CG1 4.27Å; V330-V374 HydrophobicContact CG1-CG2 4.07Å
331V93.3Very high95Very high67 Ų6721.5 Ų21.541%0.40611%0.111SC..Hα-helixtrans-58.8-45.4176.1169.30000111.7G327 I329 H335 L372G327-V331 VanDerWaalsContact O-CG2 3.29Å; G327-V331 WeakPolarHBondContact O-CG2 3.42Å; G327-V331 PolarHBondContact O-N 3.25Å; I329-V331 VanDerWaalsContact C-N 3.32Å; I329-V331 PolarHBondContact O-N 3.48Å; V331-H335 PolarHBondContact O-N 3.41Å; V331-H335 VanDerWaalsContact O-N 3.07Å; V331-L372 HydrophobicContact CG2-CD1 3.63Å
332R92.4Very high95.2Very high37 Ų3721.3 Ų21.314%0.1411%0.11CC..Hα-helixtrans-65.2-41.6178.3-69.6177.4-177134.54.9111.7Q328 I329 V330 H335 L336 L574 E670Q328-R332 WeakPolarHBondContact O-CG 3.45Å; Q328-R332 PolarHBondContact O-N 2.97Å; I329-R332 PolarHBondContact O-N 3.13Å; I329-R332 VanDerWaalsContact O-N 3.13Å; V330-R332 PolarHBondContact O-N 3.42Å; R332-H335 WeakPolarHBondContact O-CB 3.16Å; R332-H335 PolarHBondContact O-N 3.29Å; R332-L336 PolarHBondContact O-N 3.37Å; R332-L574 HydrophobicContact CB-CD2 4.31Å; R332-E670 IonicContact CZ-OE2 3.75Å; R332-E670 IonicContact NH1-OE2 3.95Å; R332-E670 IonicContact NH2-OE2 3.36Å; R332-E670 PolarHBondContact NH2-OE2 3.13Å
333M95.3Very high95.2Very high5 Ų518.9 Ų18.93%0.02510%0.098CC..Hα-helixtrans-74.6-34.3-177.6-59-65.3160.400111.9L311 I329 V330 H335 L336 K337 A338 F542 A545 L549L311-M333 HydrophobicContact CD2-CE 4.48Å; L311-M333 HydrophobicContact CD2-CG 3.7Å; L311-M333 HydrophobicContact CD2-SD 4.29Å; I329-M333 HydrophobicContact CG2-CE 4.44Å; I329-M333 HydrophobicContact CG2-CG 4.13Å; I329-M333 WeakPolarHBondContact O-CG 3.42Å; I329-M333 PolarHBondContact O-N 2.88Å; V330-M333 PolarHBondContact O-N 3.24Å; M333-H335 VanDerWaalsContact C-N 3.29Å; M333-H335 PolarHBondContact O-N 3.42Å; M333-L336 CarbonylContact O-C 3.45Å; M333-L336 VanDerWaalsContact O-C 3.3Å; M333-L336 WeakPolarHBondContact O-CA 3.5Å; M333-L336 WeakPolarHBondContact O-CB 3.46Å; M333-L336 PolarHBondContact O-N 3.24Å; M333-L336 HydrophobicContact SD-CD1 4.26Å; M333-K337 PolarHBondContact O-N 3.2Å; M333-A338 HydrophobicContact CB-CB 3.9Å; M333-A338 WeakPolarHBondContact O-CB 3.37Å; M333-A338 PolarHBondContact O-N 2.99Å; M333-F542 HydrophobicContact CE-CD1 4.41Å; M333-A545 HydrophobicContact CE-CB 3.97Å; M333-A545 HydrophobicContact SD-CB 3.93Å; M333-L549 HydrophobicContact CB-CD1 4.37Å; M333-L549 HydrophobicContact SD-CD1 3.76Å
334A95.5Very high95.4Very high2 Ų219.2 Ų19.22%0.01710%0.096CC..Hα-helixtrans-62.8-36.6170.100000111.3V330 L336 K337 L372 V374V330-A334 WeakPolarHBondContact O-CB 3.32Å; V330-A334 PolarHBondContact O-N 3.01Å; A334-L336 PolarHBondContact O-N 2.94Å; A334-K337 WeakPolarHBondContact O-CA 3.38Å; A334-K337 PolarHBondContact O-N 3.41Å; A334-L372 HydrophobicContact CB-CB 4.27Å; A334-V374 HydrophobicContact CB-CG2 3.89Å
335H94.5Very high95.5Very high13 Ų1313.7 Ų13.76%0.067%0.071CC..Hα-helixtrans-61.4-30.1171.4-169.679.3000112.8H274 Q278 V331 R332 M333 K337 H573H274-H335 AromaticContact CD2-ND1 3.47Å; H274-H335 PolarHBondContact CD2-ND1 3.4Å; Q278-H335 WeakPolarHBondContact CG-NE2 3.4Å; Q278-H335 PolarHBondContact NE2-NE2 3.24Å; V331-H335 PolarHBondContact O-N 3.41Å; V331-H335 VanDerWaalsContact O-N 3.07Å; R332-H335 WeakPolarHBondContact O-CB 3.16Å; R332-H335 PolarHBondContact O-N 3.29Å; M333-H335 VanDerWaalsContact C-N 3.29Å; M333-H335 PolarHBondContact O-N 3.42Å; H335-K337 PolarHBondContact O-N 2.82Å; H335-H573 AromaticContact NE2-ND1 3.78Å
336L95.9Very high95.5Very high1 Ų117 Ų171%0.0059%0.086CC..THydrogen-bonded Turntrans-87.313.8171.2-59.4175.4000113.3P162 R332 M333 A334 A338 V546 L549 H573 L574P162-L336 WeakPolarHBondContact CG-O 3.48Å; R332-L336 PolarHBondContact O-N 3.37Å; M333-L336 CarbonylContact O-C 3.45Å; M333-L336 VanDerWaalsContact O-C 3.3Å; M333-L336 WeakPolarHBondContact O-CA 3.5Å; M333-L336 WeakPolarHBondContact O-CB 3.46Å; M333-L336 PolarHBondContact O-N 3.24Å; M333-L336 HydrophobicContact SD-CD1 4.26Å; A334-L336 PolarHBondContact O-N 2.94Å; L336-A338 VanDerWaalsContact C-N 3.29Å; L336-A338 PolarHBondContact O-N 3.36Å; L336-V546 HydrophobicContact CD1-CG2 3.74Å; L336-L549 HydrophobicContact CB-CB 4.43Å; L336-L549 HydrophobicContact CB-CD1 3.95Å; L336-L549 HydrophobicContact CD1-CD1 4.22Å; L336-H573 HydrophobicContact CD2-CB 4.04Å; L336-L574 HydrophobicContact CD1-CD2 4.02Å
337K97.1Very high95.4Very high2 Ų217.7 Ų17.71%0.0099%0.09CC..THydrogen-bonded Turntrans61.627.8178.9-49.7178.5-179.21700114.6P162 Y250 Y271 D302 R309 M333 A334 H335 W553P162-K337 HydrophobicContact CG-CD 4.26Å; P162-K337 HydrophobicContact CG-CG 4.46Å; Y250-K337 PolarHBondContact OH-NZ 3.11Å; Y271-K337 HydrophobicContact CD1-CB 3.96Å; Y271-K337 HydrophobicContact CD1-CD 4.38Å; Y271-K337 HydrophobicContact CD1-CG 3.86Å; Y271-K337 HydrophobicContact CE1-CB 4.05Å; Y271-K337 HydrophobicContact CE1-CG 4.45Å; Y271-K337 HydrophobicContact CG-CD 4.3Å; Y271-K337 HydrophobicContact CG-CG 4.28Å; D302-K337 IonicContact OD2-NZ 2.8Å; D302-K337 PolarHBondContact OD2-NZ 2.93Å; R309-K337 PolarHBondContact NE-O 3.31Å; M333-K337 PolarHBondContact O-N 3.2Å; A334-K337 WeakPolarHBondContact O-CA 3.38Å; A334-K337 PolarHBondContact O-N 3.41Å; H335-K337 PolarHBondContact O-N 2.82Å; K337-W553 HydrophobicContact CB-CD2 4.42Å; K337-W553 HydrophobicContact CB-CE3 3.68Å; K337-W553 HydrophobicContact CB-CZ3 3.87Å; K337-W553 HydrophobicContact CD-CD2 3.53Å; K337-W553 HydrophobicContact CD-CE3 3.44Å; K337-W553 VanDerWaalsContact CD-CE3 3.44Å; K337-W553 HydrophobicContact CD-CG 4.33Å; K337-W553 HydrophobicContact CD-CH2 3.61Å; K337-W553 HydrophobicContact CD-CZ2 3.66Å; K337-W553 HydrophobicContact CD-CZ3 3.49Å; K337-W553 VanDerWaalsContact CD-CZ3 3.49Å; K337-W553 HydrophobicContact CG-CE3 4.23Å; K337-W553 HydrophobicContact CG-CZ3 4.27Å
338A97.7Very high95.2Very high3 Ų324.5 Ų24.53%0.02511%0.112CC..  trans-61.3148164.200000110.2R309 M333 L336 L549R309-A338 WeakPolarHBondContact O-CA 3.39Å; M333-A338 HydrophobicContact CB-CB 3.9Å; M333-A338 WeakPolarHBondContact O-CB 3.37Å; M333-A338 PolarHBondContact O-N 2.99Å; L336-A338 VanDerWaalsContact C-N 3.29Å; L336-A338 PolarHBondContact O-N 3.36Å; A338-L549 HydrophobicContact CB-CD1 3.98Å; A338-L549 HydrophobicContact CB-CD2 3.8Å
339N97.6Very high95Very high10 Ų1022.4 Ų22.45%0.05310%0.103CC..  trans-131.7-5.3-17970.8-12.7000114.4Y271 R307 R309 Q375Y271-N339 WeakPolarHBondContact OH-CB 3.31Å; R307-N339 PolarHBondContact O-ND2 2.99Å; R309-N339 PolarHBondContact N-OD1 3.26Å; R309-N339 PolarHBondContact NH2-ND2 3.37Å; R309-N339 PolarHBondContact O-N 3.37Å; R309-N339 PolarHBondContact O-OD1 2.99Å; N339-Q375 PolarHBondContact O-N 2.98Å
340H98.2Very high94.6Very high18 Ų1829.1 Ų29.18%0.08313%0.134CC..EExtended strand (participates in β ladder)trans-132.9139.7172.8-66.270.3000110.4R309 A310 L311 L342 Q375 F437R309-H340 PolarHBondContact O-N 3.43Å; A310-H340 VanDerWaalsContact CA-O 3.29Å; A310-H340 WeakPolarHBondContact CA-O 3.4Å; A310-H340 HydrophobicContact CB-CB 3.7Å; L311-H340 PolarHBondContact N-O 3.33Å; H340-L342 HydrophobicContact CB-CD1 4.17Å; H340-Q375 CarbonylContact C-O 3.54Å; H340-Q375 WeakPolarHBondContact CA-O 3.32Å; H340-Q375 PolarHBondContact NE2-OE1 3.3Å; H340-F437 AromaticContact CD2-CZ 3.77Å
341L98Very high94.3Very high4 Ų432.9 Ų32.92%0.02115%0.154CC..EExtended strand (participates in β ladder)trans-121.7111.5171.2179.274.8000109.1L311 L313 I326 V330 I343 V374 Q375 L376 V377L311-L341 HydrophobicContact CB-CD1 4.32Å; L311-L341 HydrophobicContact CD2-CD1 4.06Å; L311-L341 HydrophobicContact CG-CD1 4.24Å; L311-L341 CarbonylContact O-C 3.52Å; L311-L341 WeakPolarHBondContact O-CA 3.19Å; L313-L341 HydrophobicContact CD1-CD1 4.02Å; L313-L341 HydrophobicContact CG-CD1 4.13Å; I326-L341 HydrophobicContact CG2-CD2 3.92Å; V330-L341 HydrophobicContact CG2-CD1 4.2Å; V330-L341 HydrophobicContact CG2-CD2 3.37Å; V330-L341 HydrophobicContact CG2-CG 4.25Å; L341-I343 HydrophobicContact CD2-CD1 4.04Å; L341-I343 HydrophobicContact CD2-CG1 4.12Å; L341-I343 HydrophobicContact CG-CG1 4.17Å; L341-V374 HydrophobicContact CB-CG1 3.95Å; L341-Q375 PolarHBondContact N-O 3.3Å; L341-L376 HydrophobicContact CD2-CD1 3.92Å; L341-L376 HydrophobicContact CG-CD1 4.45Å; L341-V377 PolarHBondContact O-N 2.97Å
342L97.7Very high94.1Very high0 Ų034.5 Ų34.50%017%0.168CC..EExtended strand (participates in β ladder)trans-91.6129.4173.3-7766.2000109.1A310 L311 L312 L313 H340 V377 H410 I464A310-L342 HydrophobicContact CB-CD1 4.01Å; L311-L342 PolarHBondContact O-N 2.66Å; L312-L342 CarbonylContact C-O 3.59Å; L312-L342 WeakPolarHBondContact CA-O 3.3Å; L312-L342 HydrophobicContact CB-CB 3.93Å; L312-L342 HydrophobicContact CD1-CB 4.14Å; L312-L342 HydrophobicContact CD1-CD2 4.04Å; L312-L342 HydrophobicContact CG-CB 3.95Å; L313-L342 PolarHBondContact N-O 3.3Å; H340-L342 HydrophobicContact CB-CD1 4.17Å; L342-V377 VanDerWaalsContact CA-O 3.29Å; L342-V377 WeakPolarHBondContact CA-O 3.32Å; L342-V377 HydrophobicContact CD1-CB 3.87Å; L342-V377 HydrophobicContact CD1-CG1 4.29Å; L342-V377 HydrophobicContact CD1-CG2 3.98Å; L342-V377 HydrophobicContact CG-CB 3.8Å; L342-V377 HydrophobicContact CG-CG1 3.91Å; L342-V377 HydrophobicContact CG-CG2 4.45Å; L342-H410 HydrophobicContact CD2-CB 3.94Å; L342-H410 HydrophobicContact CG-CB 4.38Å; L342-I464 HydrophobicContact CD2-CD1 4.02Å
343I96.4Very high93.9Very high1 Ų134.3 Ų34.31%0.00517%0.169CC..EExtended strand (participates in β ladder)trans-117.5106.3174.2-54.5-175.9000108.7F315 I326 L341 F345 L365 L376 V377 S379F315-I343 HydrophobicContact CD2-CG2 3.45Å; F315-I343 VanDerWaalsContact CD2-CG2 3.45Å; F315-I343 HydrophobicContact CE2-CG2 3.39Å; F315-I343 HydrophobicContact CG-CG2 4.3Å; F315-I343 HydrophobicContact CZ-CG2 4.17Å; I326-I343 HydrophobicContact CD1-CD1 4.4Å; I326-I343 HydrophobicContact CG2-CD1 4.37Å; L341-I343 HydrophobicContact CD2-CD1 4.04Å; L341-I343 HydrophobicContact CD2-CG1 4.12Å; L341-I343 HydrophobicContact CG-CG1 4.17Å; I343-F345 HydrophobicContact CB-CE2 4.13Å; I343-F345 HydrophobicContact CG2-CD2 4.4Å; I343-F345 HydrophobicContact CG2-CE1 4.46Å; I343-F345 HydrophobicContact CG2-CE2 3.52Å; I343-F345 HydrophobicContact CG2-CZ 3.57Å; I343-F345 WeakPolarHBondContact O-CD2 3.44Å; I343-L365 HydrophobicContact CD1-CD2 3.66Å; I343-L376 HydrophobicContact CD1-CD1 3.62Å; I343-L376 HydrophobicContact CG1-CD1 3.97Å; I343-V377 PolarHBondContact N-O 2.84Å; I343-S379 WeakPolarHBondContact O-CA 3.49Å; I343-S379 VanDerWaalsContact O-CB 3.29Å; I343-S379 WeakPolarHBondContact O-CB 3.34Å; I343-S379 PolarHBondContact O-N 3.21Å
344R95.7Very high93.7Very high27 Ų2737.8 Ų37.810%0.10220%0.198CC..EExtended strand (participates in β ladder)trans-89.1125.6-173.2179.2173.9-178.8-82.5-2.3112.1L312 L313 D314 F315 S316 S379 D381L312-R344 HydrophobicContact CD2-CB 4.23Å; L312-R344 HydrophobicContact CG-CB 4.5Å; L313-R344 PolarHBondContact O-N 2.99Å; D314-R344 WeakPolarHBondContact OD1-CD 3.31Å; D314-R344 IonicContact OD1-CZ 3.88Å; D314-R344 IonicContact OD1-NH1 3.35Å; D314-R344 PolarHBondContact OD1-NH1 3.39Å; D314-R344 IonicContact OD2-NH1 3.79Å; F315-R344 WeakPolarHBondContact CA-O 3.35Å; F315-R344 WeakPolarHBondContact CB-O 3.32Å; F315-R344 PolarHBondContact N-O 3.45Å; S316-R344 VanDerWaalsContact CB-NH1 3.35Å; S316-R344 PolarHBondContact OG-NH1 3.41Å; S316-R344 VanDerWaalsContact OG-NH1 3.13Å; R344-S379 CarbonylContact C-O 3.53Å; R344-S379 VanDerWaalsContact CA-CB 3.47Å; R344-S379 WeakPolarHBondContact CA-O 3.17Å; R344-S379 WeakPolarHBondContact CA-OG 3.33Å; R344-S379 VanDerWaalsContact CB-OG 3.29Å; R344-S379 WeakPolarHBondContact CB-OG 3.41Å; R344-S379 WeakPolarHBondContact CG-OG 3.45Å; R344-D381 IonicContact CZ-OD2 3.4Å; R344-D381 IonicContact NE-OD2 2.96Å; R344-D381 IonicContact NH2-OD2 2.97Å; R344-D381 PolarHBondContact NH2-OD2 3.16Å
345F95Very high93.6Very high8 Ų839.2 Ų39.24%0.03521%0.205CC..EExtended strand (participates in β ladder)trans-115.2133.3170.5-58.6-85.8000109.2F315 I343 L355 P356 F357 S379 I380 D381 F399 F403F315-F345 HydrophobicContact CB-CD1 4.27Å; F315-F345 HydrophobicContact CB-CE1 4.27Å; F315-F345 AromaticContact CD2-CE1 3.77Å; F315-F345 HydrophobicContact CD2-CE1 3.77Å; F315-F345 AromaticContact CD2-CZ 3.96Å; F315-F345 HydrophobicContact CD2-CZ 3.96Å; I343-F345 HydrophobicContact CB-CE2 4.13Å; I343-F345 HydrophobicContact CG2-CD2 4.4Å; I343-F345 HydrophobicContact CG2-CE1 4.46Å; I343-F345 HydrophobicContact CG2-CE2 3.52Å; I343-F345 HydrophobicContact CG2-CZ 3.57Å; I343-F345 WeakPolarHBondContact O-CD2 3.44Å; F345-L355 HydrophobicContact CB-CD2 4.36Å; F345-L355 HydrophobicContact CD1-CD2 3.92Å; F345-L355 HydrophobicContact CD2-CD2 4.34Å; F345-L355 HydrophobicContact CE1-CD2 4.29Å; F345-L355 HydrophobicContact CG-CD2 3.94Å; F345-P356 HydrophobicContact CD1-CG 4.3Å; F345-P356 HydrophobicContact CE1-CG 3.72Å; F345-F357 HydrophobicContact CE1-CD2 4.19Å; F345-F357 HydrophobicContact CE1-CE2 4.04Å; F345-F357 HydrophobicContact CZ-CD2 4.05Å; F345-F357 AromaticContact CZ-CE2 3.98Å; F345-F357 HydrophobicContact CZ-CE2 3.98Å; F345-S379 PolarHBondContact N-O 2.8Å; F345-I380 WeakPolarHBondContact O-CA 3.27Å; F345-D381 PolarHBondContact O-N 2.99Å; F345-F399 HydrophobicContact CB-CE2 4.27Å; F345-F399 AromaticContact CD2-CE2 3.81Å; F345-F399 HydrophobicContact CD2-CE2 3.81Å; F345-F399 HydrophobicContact CD2-CZ 4.14Å; F345-F399 HydrophobicContact CG-CE2 4.3Å; F345-F403 HydrophobicContact CD2-CZ 4.45Å; F345-F403 AromaticContact CE2-CZ 3.79Å; F345-F403 HydrophobicContact CE2-CZ 3.79Å; F345-F403 HydrophobicContact CZ-CZ 4.47Å
346E93.5Very high93.4Very high76 Ų7641.6 Ų41.636%0.35522%0.222SC..EExtended strand (participates in β ladder)trans-101.4124.2167.9-178.5179.5-14900108.6S316 N383S316-E346 WeakPolarHBondContact CB-OE2 3.41Å; E346-N383 HydrophobicContact CG-CB 4.22Å; E346-N383 VanDerWaalsContact OE1-CA 3.31Å; E346-N383 WeakPolarHBondContact OE1-CA 3.43Å
347V93.1Very high93.2Very high14 Ų1442.3 Ų42.39%0.08523%0.225CC..EExtended strand (participates in β ladder)trans-99.8127.1178.9-178.30000109.4F353 I380 D381 L382 N383 I395V347-F353 HydrophobicContact CG1-CD2 4.11Å; V347-F353 HydrophobicContact CG2-CD2 4.1Å; V347-F353 HydrophobicContact CG2-CE2 4Å; V347-I380 HydrophobicContact CG2-CD1 4.23Å; V347-I380 HydrophobicContact CG2-CG1 4.27Å; V347-D381 PolarHBondContact N-O 3.13Å; V347-L382 HydrophobicContact CB-CD2 4.3Å; V347-N383 PolarHBondContact O-N 3.13Å; V347-N383 PolarHBondContact O-OD1 2.82Å; V347-I395 HydrophobicContact CB-CG2 4.27Å; V347-I395 HydrophobicContact CG1-CD1 4.3Å; V347-I395 HydrophobicContact CG1-CG2 3.9Å; V347-I395 HydrophobicContact CG2-CG2 4.29Å
348R90.7Very high92.9Very high155 Ų15547.8 Ų47.859%0.58525%0.25SS*.PPolyproline II helixtrans-80.5121.1169.9-66.4-178-179.1175.83.6110.2Q350 D351 N383R348-Q350 PolarHBondContact O-N 3.01Å; R348-D351 HydrophobicContact CB-CB 4.21Å; R348-D351 WeakPolarHBondContact CB-OD2 3.27Å; R348-D351 VanDerWaalsContact CD-OD2 3.29Å; R348-D351 WeakPolarHBondContact CD-OD2 3.41Å; R348-D351 PolarHBondContact O-N 3.32Å; R348-D351 VanDerWaalsContact O-N 3.14Å; R348-N383 WeakPolarHBondContact CA-OD1 3.32Å; R348-N383 HydrophobicContact CG-CB 4.4Å
349I87.2Confident92.6Very high25 Ų2551.9 Ų51.913%0.12828%0.277CS..THydrogen-bonded Turntrans-64-33.3-173.8-60.5139.8000112.2D351 L382 N383 C384 V387 R391I349-D351 VanDerWaalsContact C-N 3.25Å; I349-D351 PolarHBondContact O-N 3.48Å; I349-L382 HydrophobicContact CG1-CD2 4.37Å; I349-N383 VanDerWaalsContact CD1-OD1 3.26Å; I349-N383 WeakPolarHBondContact CD1-OD1 3.36Å; I349-N383 PolarHBondContact N-OD1 3.43Å; I349-N383 VanDerWaalsContact N-OD1 3.16Å; I349-C384 HydrophobicContact CD1-CB 3.55Å; I349-V387 HydrophobicContact CD1-CB 4.38Å; I349-V387 HydrophobicContact CD1-CG1 4.49Å; I349-V387 HydrophobicContact CD1-CG2 3.18Å; I349-V387 HydrophobicContact CG1-CG1 4.11Å; I349-V387 HydrophobicContact CG1-CG2 3.61Å; I349-V387 HydrophobicContact CG2-CG1 3.77Å; I349-V387 HydrophobicContact CG2-CG2 4.44Å; I349-R391 HydrophobicContact CG2-CG 4.17Å
350Q86.7Confident92.3Very high142 Ų14256.8 Ų56.866%0.66430%0.299SS*.THydrogen-bonded Turntrans-69.2-23.9-179.9-5988.2-300112.7R348 N383R348-Q350 PolarHBondContact O-N 3.01Å; Q350-N383 PolarHBondContact OE1-ND2 2.81Å
351D88.1Confident92Very high80 Ų8060 Ų6043%0.42831%0.313SS..SBendtrans-92.5158.1-174.1-62.8-21.8000111.1R348 I349 F353 R391R348-D351 HydrophobicContact CB-CB 4.21Å; R348-D351 WeakPolarHBondContact CB-OD2 3.27Å; R348-D351 VanDerWaalsContact CD-OD2 3.29Å; R348-D351 WeakPolarHBondContact CD-OD2 3.41Å; R348-D351 PolarHBondContact O-N 3.32Å; R348-D351 VanDerWaalsContact O-N 3.14Å; I349-D351 VanDerWaalsContact C-N 3.25Å; I349-D351 PolarHBondContact O-N 3.48Å; D351-F353 PolarHBondContact O-N 3.31Å; D351-R391 PolarHBondContact O-NH2 3.38Å
352S89.1Confident91.8Very high101 Ų10160 Ų6071%0.70631%0.313SS*.PPolyproline II helixtrans-64.7133.8167.155.80000109.8A354S352-A354 PolarHBondContact O-N 2.82Å
353F89.9Confident91.5Very high34 Ų3465.2 Ų65.215%0.14934%0.336CS..PPolyproline II helixtrans-60.7123.8177.4175.7-96.3000110.5V347 D351 L355 I395 Q398 F399V347-F353 HydrophobicContact CG1-CD2 4.11Å; V347-F353 HydrophobicContact CG2-CD2 4.1Å; V347-F353 HydrophobicContact CG2-CE2 4Å; D351-F353 PolarHBondContact O-N 3.31Å; F353-L355 HydrophobicContact CE1-CG 4.4Å; F353-L355 HydrophobicContact CE2-CD2 4.39Å; F353-L355 HydrophobicContact CZ-CD1 4.25Å; F353-L355 HydrophobicContact CZ-CD2 4.11Å; F353-L355 HydrophobicContact CZ-CG 3.83Å; F353-I395 HydrophobicContact CD2-CG2 4.03Å; F353-I395 HydrophobicContact CE2-CG2 4.48Å; F353-Q398 HydrophobicContact CD1-CB 3.56Å; F353-Q398 HydrophobicContact CD1-CG 4.49Å; F353-Q398 VanDerWaalsContact CD1-OE1 3.29Å; F353-Q398 HydrophobicContact CE1-CB 3.73Å; F353-Q398 HydrophobicContact CG-CB 4.23Å; F353-F399 HydrophobicContact CE2-CB 3.89Å; F353-F399 HydrophobicContact CE2-CD2 4Å; F353-F399 HydrophobicContact CE2-CG 4.47Å; F353-F399 VanDerWaalsContact CZ-CA 3.47Å; F353-F399 HydrophobicContact CZ-CB 3.7Å; F353-F399 AromaticContact CZ-CD2 3.92Å; F353-F399 HydrophobicContact CZ-CD2 3.92Å; F353-F399 HydrophobicContact CZ-CG 4.31Å
354A90.7Very high91.4Very high78 Ų7867.2 Ų67.265%0.64535%0.347SS*.  trans-151.1142.1173.700000109.1S352S352-A354 PolarHBondContact O-N 2.82Å
355L92.5Very high91.3Very high32 Ų3266.2 Ų66.217%0.16834%0.343CS..  trans-100.9151.3169.7-67.6177.9000109.6F345 F353 F357 L362 F399 A402 F403F345-L355 HydrophobicContact CB-CD2 4.36Å; F345-L355 HydrophobicContact CD1-CD2 3.92Å; F345-L355 HydrophobicContact CD2-CD2 4.34Å; F345-L355 HydrophobicContact CE1-CD2 4.29Å; F345-L355 HydrophobicContact CG-CD2 3.94Å; F353-L355 HydrophobicContact CE1-CG 4.4Å; F353-L355 HydrophobicContact CE2-CD2 4.39Å; F353-L355 HydrophobicContact CZ-CD1 4.25Å; F353-L355 HydrophobicContact CZ-CD2 4.11Å; F353-L355 HydrophobicContact CZ-CG 3.83Å; L355-F357 PolarHBondContact O-N 3.16Å; L355-L362 HydrophobicContact CD1-CD1 4.05Å; L355-F399 HydrophobicContact CD1-CD2 4.37Å; L355-F399 HydrophobicContact CD2-CD2 4.05Å; L355-F399 HydrophobicContact CD2-CE2 4.03Å; L355-A402 HydrophobicContact CD1-CB 3.58Å; L355-F403 HydrophobicContact CD1-CE2 3.74Å; L355-F403 HydrophobicContact CD1-CZ 4.19Å
356P91.3Very high91.3Very high62 Ų6266.5 Ų66.540%0.40335%0.345SS..SBendtrans-71.8-6.4178.629.2-34.7000113.5V320 F345 L746V320-P356 HydrophobicContact CG1-CB 4.15Å; V320-P356 HydrophobicContact CG1-CG 3.92Å; F345-P356 HydrophobicContact CD1-CG 4.3Å; F345-P356 HydrophobicContact CE1-CG 3.72Å; P356-L746 HydrophobicContact CB-CD1 3.82Å
357F92.2Very high91.3Very high17 Ų1769.5 Ų69.58%0.07535%0.353CS..SBendtrans-117143.5-178.9-56.8-72.2000111.5F315 V320 Y321 P323 I326 F345 L355 L362 L746F315-F357 AromaticContact CD2-CE2 3.9Å; F315-F357 HydrophobicContact CD2-CE2 3.9Å; F315-F357 HydrophobicContact CD2-CZ 4.32Å; F315-F357 AromaticContact CE2-CE2 3.69Å; F315-F357 HydrophobicContact CE2-CE2 3.69Å; F315-F357 AromaticContact CE2-CZ 3.8Å; F315-F357 HydrophobicContact CE2-CZ 3.8Å; V320-F357 HydrophobicContact CG1-CE2 4.13Å; V320-F357 HydrophobicContact CG1-CZ 3.8Å; Y321-F357 WeakPolarHBondContact O-CE1 3.49Å; Y321-F357 VanDerWaalsContact O-CZ 3.24Å; Y321-F357 WeakPolarHBondContact O-CZ 3.38Å; P323-F357 HydrophobicContact CG-CD1 4.04Å; P323-F357 HydrophobicContact CG-CE1 4.01Å; I326-F357 HydrophobicContact CD1-CZ 4.05Å; F345-F357 HydrophobicContact CE1-CD2 4.19Å; F345-F357 HydrophobicContact CE1-CE2 4.04Å; F345-F357 HydrophobicContact CZ-CD2 4.05Å; F345-F357 AromaticContact CZ-CE2 3.98Å; F345-F357 HydrophobicContact CZ-CE2 3.98Å; L355-F357 PolarHBondContact O-N 3.16Å; F357-L362 HydrophobicContact CB-CD1 4.32Å; F357-L362 HydrophobicContact CB-CD2 3.74Å; F357-L362 HydrophobicContact CB-CG 3.8Å; F357-L362 HydrophobicContact CD2-CD2 3.85Å; F357-L362 HydrophobicContact CG-CD2 4Å; F357-L746 HydrophobicContact CE1-CD1 4.3Å
358E90.6Very high91.3Very high116 Ų11672.1 Ų72.154%0.54237%0.366SS..  trans-67.5145.2166.8-66.6164.4176.700110.1Q360 K361 L362E358-Q360 PolarHBondContact O-N 3.5Å; E358-Q360 VanDerWaalsContact O-N 3.13Å; E358-K361 HydrophobicContact CB-CD 4.4Å; E358-K361 HydrophobicContact CB-CG 4.42Å; E358-K361 WeakPolarHBondContact O-CB 3.28Å; E358-K361 PolarHBondContact O-N 2.85Å; E358-K361 WeakPolarHBondContact OE2-CE 3.24Å; E358-K361 IonicContact OE2-NZ 3.18Å; E358-L362 PolarHBondContact O-N 3.02Å
359P90.1Very high91.5Very high89 Ų8964.7 Ų64.758%0.57834%0.338SS*.Hα-helixtrans-53.8-35.9178.9-28.235.3000113.8K361 L362 F363P359-K361 PolarHBondContact O-N 3.39Å; P359-L362 PolarHBondContact O-N 3.31Å; P359-F363 PolarHBondContact O-N 2.79Å
360Q91.7Very high91.9Very high113 Ų11368.6 Ų68.653%0.52836%0.356SS..Hα-helixtrans-61.1-42.6176.9-177.95939.300112.2E358 L362 F363 D364E358-Q360 PolarHBondContact O-N 3.5Å; E358-Q360 VanDerWaalsContact O-N 3.13Å; Q360-L362 VanDerWaalsContact C-N 3.34Å; Q360-L362 PolarHBondContact O-N 3.43Å; Q360-F363 WeakPolarHBondContact O-CB 3.47Å; Q360-F363 PolarHBondContact O-N 2.87Å; Q360-D364 PolarHBondContact NE2-OD2 3.4Å; Q360-D364 PolarHBondContact O-N 3.09Å
361K92.8Very high92.3Very high85 Ų8564.4 Ų64.437%0.3734%0.342SS..Hα-helixtrans-66.6-37.4178.9-68.5176.2177.4174.80111.5P323 E358 P359 L365P323-K361 HydrophobicContact CG-CB 4.32Å; P323-K361 HydrophobicContact CG-CD 4.14Å; E358-K361 HydrophobicContact CB-CD 4.4Å; E358-K361 HydrophobicContact CB-CG 4.42Å; E358-K361 WeakPolarHBondContact O-CB 3.28Å; E358-K361 PolarHBondContact O-N 2.85Å; E358-K361 WeakPolarHBondContact OE2-CE 3.24Å; E358-K361 IonicContact OE2-NZ 3.18Å; P359-K361 PolarHBondContact O-N 3.39Å; K361-L365 WeakPolarHBondContact O-CB 3.45Å; K361-L365 PolarHBondContact O-N 3.49Å
362L92.5Very high92.6Very high5 Ų561.5 Ų61.53%0.02633%0.327CS..Hα-helixtrans-66.2-39.7174.4-64.9176.5000111.6L355 F357 E358 P359 Q360 L365 N366 F403L355-L362 HydrophobicContact CD1-CD1 4.05Å; F357-L362 HydrophobicContact CB-CD1 4.32Å; F357-L362 HydrophobicContact CB-CD2 3.74Å; F357-L362 HydrophobicContact CB-CG 3.8Å; F357-L362 HydrophobicContact CD2-CD2 3.85Å; F357-L362 HydrophobicContact CG-CD2 4Å; E358-L362 PolarHBondContact O-N 3.02Å; P359-L362 PolarHBondContact O-N 3.31Å; Q360-L362 VanDerWaalsContact C-N 3.34Å; Q360-L362 PolarHBondContact O-N 3.43Å; L362-L365 PolarHBondContact O-N 3.4Å; L362-N366 PolarHBondContact O-N 3.41Å; L362-F403 HydrophobicContact CB-CE1 4.5Å; L362-F403 HydrophobicContact CD1-CD1 4.28Å; L362-F403 HydrophobicContact CD1-CE1 3.9Å; L362-F403 HydrophobicContact CD1-CE2 4.39Å; L362-F403 HydrophobicContact CD1-CZ 3.95Å; L362-F403 HydrophobicContact CD2-CE1 3.86Å; L362-F403 HydrophobicContact CD2-CZ 4.27Å; L362-F403 HydrophobicContact CG-CE1 4.31Å
363F92.5Very high92.9Very high109 Ų10958.4 Ų58.448%0.47830%0.301SS..Hα-helixtrans-63.5-47.4174.7179.9-93.7000112.1P359 Q360 L365 N366 R367P359-F363 PolarHBondContact O-N 2.79Å; Q360-F363 WeakPolarHBondContact O-CB 3.47Å; Q360-F363 PolarHBondContact O-N 2.87Å; F363-L365 VanDerWaalsContact C-N 3.3Å; F363-L365 PolarHBondContact O-N 3.21Å; F363-N366 WeakPolarHBondContact O-CB 3.16Å; F363-N366 PolarHBondContact O-N 3.08Å; F363-R367 PolarHBondContact O-N 3.36Å
364D93.2Very high93.2Very high44 Ų4457.1 Ų57.124%0.23530%0.296CS..Hα-helixtrans-62.1-39.1177.1-76.6-48.5000111.8Q360 R367 I368Q360-D364 PolarHBondContact NE2-OD2 3.4Å; Q360-D364 PolarHBondContact O-N 3.09Å; D364-R367 PolarHBondContact O-N 2.91Å; D364-R367 IonicContact OD1-CZ 2.94Å; D364-R367 IonicContact OD1-NH1 3.13Å; D364-R367 IonicContact OD1-NH2 3.34Å; D364-R367 PolarHBondContact OD1-NH2 2.99Å; D364-I368 WeakPolarHBondContact O-CG1 3.5Å; D364-I368 PolarHBondContact O-N 3.16Å
365L93.5Very high93.5Very high6 Ų656.1 Ų56.13%0.03128%0.278CS..Hα-helixtrans-62.2-43.9174177.762.2000112.1I326 I343 K361 L362 F363 R367 I368 C369 L376I326-L365 HydrophobicContact CB-CD1 4.19Å; I326-L365 HydrophobicContact CD1-CD2 4.17Å; I326-L365 HydrophobicContact CG2-CD1 3.67Å; I326-L365 HydrophobicContact CG2-CD2 4.07Å; I343-L365 HydrophobicContact CD1-CD2 3.66Å; K361-L365 WeakPolarHBondContact O-CB 3.45Å; K361-L365 PolarHBondContact O-N 3.49Å; L362-L365 PolarHBondContact O-N 3.4Å; F363-L365 VanDerWaalsContact C-N 3.3Å; F363-L365 PolarHBondContact O-N 3.21Å; L365-R367 VanDerWaalsContact C-N 3.34Å; L365-R367 PolarHBondContact O-N 3.01Å; L365-I368 PolarHBondContact O-N 3.21Å; L365-C369 PolarHBondContact O-N 2.68Å; L365-C369 PolarHBondContact O-SG 3.07Å; L365-L376 HydrophobicContact CD2-CD1 4.45Å; L365-L376 HydrophobicContact CG-CD2 4.42Å
366N94.8Very high93.7Very high14 Ų1454.7 Ų54.78%0.07527%0.271CS..Hα-helixtrans-58.4-47176.2-171.954.8000111.1L362 F363 I368 C369 E370 L376L362-N366 PolarHBondContact O-N 3.41Å; F363-N366 WeakPolarHBondContact O-CB 3.16Å; F363-N366 PolarHBondContact O-N 3.08Å; N366-I368 VanDerWaalsContact C-N 3.31Å; N366-I368 PolarHBondContact O-N 3.33Å; N366-C369 PolarHBondContact O-N 2.89Å; N366-C369 VanDerWaalsContact O-N 3.15Å; N366-E370 PolarHBondContact ND2-OE1 3.19Å; N366-E370 WeakPolarHBondContact O-CG 3.43Å; N366-E370 PolarHBondContact O-N 2.78Å; N366-L376 HydrophobicContact CB-CD2 3.87Å; N366-L376 WeakPolarHBondContact OD1-CB 3.43Å
367R93.9Very high94.1Very high138 Ų13851.8 Ų51.852%0.52125%0.251SS..Hα-helixtrans-58.8-40.7177.6-172.8-177.266.2-151.3-14.3112.4F363 D364 L365 S371F363-R367 PolarHBondContact O-N 3.36Å; D364-R367 PolarHBondContact O-N 2.91Å; D364-R367 IonicContact OD1-CZ 2.94Å; D364-R367 IonicContact OD1-NH1 3.13Å; D364-R367 IonicContact OD1-NH2 3.34Å; D364-R367 PolarHBondContact OD1-NH2 2.99Å; L365-R367 VanDerWaalsContact C-N 3.34Å; L365-R367 PolarHBondContact O-N 3.01Å; R367-S371 WeakPolarHBondContact O-CB 3.1Å; R367-S371 PolarHBondContact O-N 3.29Å
368I93.6Very high94.3Very high69 Ų6951 Ų5135%0.35425%0.248SC..Hα-helixtrans-63.6-47.4176.5-69.1166.2000110.2D364 L365 N366 E370 S371 L372D364-I368 WeakPolarHBondContact O-CG1 3.5Å; D364-I368 PolarHBondContact O-N 3.16Å; L365-I368 PolarHBondContact O-N 3.21Å; N366-I368 VanDerWaalsContact C-N 3.31Å; N366-I368 PolarHBondContact O-N 3.33Å; I368-E370 PolarHBondContact O-N 3.48Å; I368-S371 PolarHBondContact O-N 3.46Å; I368-S371 PolarHBondContact O-OG 3.47Å; I368-L372 HydrophobicContact CG2-CD1 4.09Å; I368-L372 WeakPolarHBondContact O-CG 3.27Å; I368-L372 PolarHBondContact O-N 2.87Å
369C95.7Very high94.6Very high0 Ų045.5 Ų45.50%022%0.222CC..Hα-helixtrans-58.9-49178.9-63.50000111.2L365 N366 S371 L372 Q373 V374 L376L365-C369 PolarHBondContact O-N 2.68Å; L365-C369 PolarHBondContact O-SG 3.07Å; N366-C369 PolarHBondContact O-N 2.89Å; N366-C369 VanDerWaalsContact O-N 3.15Å; C369-S371 VanDerWaalsContact C-N 3.33Å; C369-S371 PolarHBondContact O-N 3.05Å; C369-L372 CarbonylContact O-C 3.54Å; C369-L372 WeakPolarHBondContact O-CA 3.38Å; C369-L372 PolarHBondContact O-N 3.43Å; C369-Q373 PolarHBondContact O-N 3.34Å; C369-Q373 VanDerWaalsContact O-N 3.15Å; C369-V374 CarbonylContact C-O 3.57Å; C369-V374 HydrophobicContact CB-CB 4.35Å; C369-V374 WeakPolarHBondContact CB-O 3.48Å; C369-V374 PolarHBondContact O-N 3.08Å; C369-L376 HydrophobicContact CB-CB 4.31Å
370E94.5Very high94.9Very high106 Ų10641.3 Ų41.350%0.49520%0.195SC..Hα-helixtrans-60-40.8178.9-73.2175.9176.800112.5N366 I368 L372 Q373 V374N366-E370 PolarHBondContact ND2-OE1 3.19Å; N366-E370 WeakPolarHBondContact O-CG 3.43Å; N366-E370 PolarHBondContact O-N 2.78Å; I368-E370 PolarHBondContact O-N 3.48Å; E370-L372 PolarHBondContact O-N 3.34Å; E370-Q373 PolarHBondContact O-N 2.89Å; E370-V374 PolarHBondContact N-O 3.4Å
371S94.3Very high95.1Very high55 Ų5536 Ų3639%0.38517%0.17SC..Hα-helixtrans-60.6-34.3176.276.70000112.3V205 R367 I368 C369 Q373V205-S371 WeakPolarHBondContact CG1-O 3.36Å; R367-S371 WeakPolarHBondContact O-CB 3.1Å; R367-S371 PolarHBondContact O-N 3.29Å; I368-S371 PolarHBondContact O-N 3.46Å; I368-S371 PolarHBondContact O-OG 3.47Å; C369-S371 VanDerWaalsContact C-N 3.33Å; C369-S371 PolarHBondContact O-N 3.05Å; S371-Q373 VanDerWaalsContact C-N 3.27Å; S371-Q373 PolarHBondContact O-N 3.33Å
372L95.1Very high95.1Very high19 Ų1932 Ų3210%0.09915%0.153CC..THydrogen-bonded Turntrans-877.3177-65170.5000113.1V205 L206 V330 V331 A334 I368 C369 E370 V374V205-L372 HydrophobicContact CG1-CD2 3.96Å; L206-L372 HydrophobicContact CD2-CD2 4.37Å; V330-L372 HydrophobicContact CG1-CD1 3.83Å; V331-L372 HydrophobicContact CG2-CD1 3.63Å; A334-L372 HydrophobicContact CB-CB 4.27Å; I368-L372 HydrophobicContact CG2-CD1 4.09Å; I368-L372 WeakPolarHBondContact O-CG 3.27Å; I368-L372 PolarHBondContact O-N 2.87Å; C369-L372 CarbonylContact O-C 3.54Å; C369-L372 WeakPolarHBondContact O-CA 3.38Å; C369-L372 PolarHBondContact O-N 3.43Å; E370-L372 PolarHBondContact O-N 3.34Å; L372-V374 HydrophobicContact CB-CG2 4.36Å; L372-V374 PolarHBondContact O-N 3.27Å
373Q95Very high95Very high36 Ų3634.4 Ų34.417%0.16817%0.166CC..THydrogen-bonded Turntrans61.829.9-179.4-51.4164-21.900112.4L266 V267 C369 E370 S371L266-Q373 PolarHBondContact O-NE2 3.29Å; V267-Q373 HydrophobicContact CG1-CB 4.32Å; V267-Q373 HydrophobicContact CG2-CB 4.45Å; V267-Q373 HydrophobicContact CG2-CG 4.49Å; V267-Q373 PolarHBondContact O-OE1 3.41Å; C369-Q373 PolarHBondContact O-N 3.34Å; C369-Q373 VanDerWaalsContact O-N 3.15Å; E370-Q373 PolarHBondContact O-N 2.89Å; S371-Q373 VanDerWaalsContact C-N 3.27Å; S371-Q373 PolarHBondContact O-N 3.33Å
374V97.3Very high94.8Very high6 Ų631 Ų314%0.03616%0.155CC..  trans-109.7128.9173.9179.80000108.4V330 A334 L341 C369 E370 L372V330-V374 HydrophobicContact CG1-CB 4.16Å; V330-V374 HydrophobicContact CG1-CG1 4.27Å; V330-V374 HydrophobicContact CG1-CG2 4.07Å; A334-V374 HydrophobicContact CB-CG2 3.89Å; L341-V374 HydrophobicContact CB-CG1 3.95Å; C369-V374 CarbonylContact C-O 3.57Å; C369-V374 HydrophobicContact CB-CB 4.35Å; C369-V374 WeakPolarHBondContact CB-O 3.48Å; C369-V374 PolarHBondContact O-N 3.08Å; E370-V374 PolarHBondContact N-O 3.4Å; L372-V374 HydrophobicContact CB-CG2 4.36Å; L372-V374 PolarHBondContact O-N 3.27Å
375Q96.9Very high94.4Very high58 Ų5831.4 Ų31.427%0.27116%0.16SC..EExtended strand (participates in β ladder)trans-86.4121.5176.7-170.61681200110.7N339 H340 L341 C408N339-Q375 PolarHBondContact O-N 2.98Å; H340-Q375 CarbonylContact C-O 3.54Å; H340-Q375 WeakPolarHBondContact CA-O 3.32Å; H340-Q375 PolarHBondContact NE2-OE1 3.3Å; L341-Q375 PolarHBondContact N-O 3.3Å; Q375-C408 VanDerWaalsContact CD-SG 3.52Å; Q375-C408 PolarHBondContact NE2-SG 3.02Å
376L97.2Very high93.9Very high2 Ų238.9 Ų38.91%0.0120%0.195CC..EExtended strand (participates in β ladder)trans-74.6131.6171.6-177.465.2000110L341 I343 L365 N366 C369L341-L376 HydrophobicContact CD2-CD1 3.92Å; L341-L376 HydrophobicContact CG-CD1 4.45Å; I343-L376 HydrophobicContact CD1-CD1 3.62Å; I343-L376 HydrophobicContact CG1-CD1 3.97Å; L365-L376 HydrophobicContact CD2-CD1 4.45Å; L365-L376 HydrophobicContact CG-CD2 4.42Å; N366-L376 HydrophobicContact CB-CD2 3.87Å; N366-L376 WeakPolarHBondContact OD1-CB 3.43Å; C369-L376 HydrophobicContact CB-CB 4.31Å
377V97.9Very high93.6Very high0 Ų039.2 Ų39.20%020%0.197CC..EExtended strand (participates in β ladder)trans-125.9102.6179.6-175.30000108.4L341 L342 I343 S379 C408 H410 F437L341-V377 PolarHBondContact O-N 2.97Å; L342-V377 VanDerWaalsContact CA-O 3.29Å; L342-V377 WeakPolarHBondContact CA-O 3.32Å; L342-V377 HydrophobicContact CD1-CB 3.87Å; L342-V377 HydrophobicContact CD1-CG1 4.29Å; L342-V377 HydrophobicContact CD1-CG2 3.98Å; L342-V377 HydrophobicContact CG-CB 3.8Å; L342-V377 HydrophobicContact CG-CG1 3.91Å; L342-V377 HydrophobicContact CG-CG2 4.45Å; I343-V377 PolarHBondContact N-O 2.84Å; V377-S379 PolarHBondContact O-N 3.5Å; V377-C408 HydrophobicContact CG1-CB 4.14Å; V377-C408 HydrophobicContact CG2-CB 3.89Å; V377-H410 HydrophobicContact CG1-CB 3.92Å; V377-F437 HydrophobicContact CG1-CD2 3.81Å; V377-F437 HydrophobicContact CG1-CE2 4.17Å; V377-F437 HydrophobicContact CG2-CD2 4.49Å; V377-F437 HydrophobicContact CG2-CE2 4.02Å
378P97.4Very high93.5Very high1 Ų137.5 Ų37.51%0.00620%0.199CC..EExtended strand (participates in β ladder)trans-64131.9171.328.8-36.1000109.8F399 F403 V406 C408 I409 H410P378-F399 HydrophobicContact CB-CE1 3.75Å; P378-F399 HydrophobicContact CB-CZ 3.75Å; P378-F399 HydrophobicContact CG-CE1 4.45Å; P378-F403 HydrophobicContact CB-CD1 3.74Å; P378-F403 HydrophobicContact CB-CD2 3.69Å; P378-F403 HydrophobicContact CB-CE1 3.7Å; P378-F403 HydrophobicContact CB-CE2 3.68Å; P378-F403 HydrophobicContact CB-CG 3.74Å; P378-F403 HydrophobicContact CB-CZ 3.69Å; P378-F403 HydrophobicContact CG-CB 4.39Å; P378-F403 HydrophobicContact CG-CD1 4.19Å; P378-F403 HydrophobicContact CG-CD2 4.25Å; P378-F403 HydrophobicContact CG-CG 4.01Å; P378-V406 HydrophobicContact CG-CG2 3.86Å; P378-C408 WeakPolarHBondContact CD-O 3.49Å; P378-I409 HydrophobicContact CG-CG1 4.49Å; P378-I409 WeakPolarHBondContact O-CG1 3.47Å; P378-H410 PolarHBondContact O-N 3.28Å
379S97.2Very high93.4Very high0 Ų036 Ų360%019%0.192CC..EExtended strand (participates in β ladder)trans-115.8126.6179.2161.90000109.6I343 R344 F345 V377 H410I343-S379 WeakPolarHBondContact O-CA 3.49Å; I343-S379 VanDerWaalsContact O-CB 3.29Å; I343-S379 WeakPolarHBondContact O-CB 3.34Å; I343-S379 PolarHBondContact O-N 3.21Å; R344-S379 CarbonylContact C-O 3.53Å; R344-S379 VanDerWaalsContact CA-CB 3.47Å; R344-S379 WeakPolarHBondContact CA-O 3.17Å; R344-S379 WeakPolarHBondContact CA-OG 3.33Å; R344-S379 VanDerWaalsContact CB-OG 3.29Å; R344-S379 WeakPolarHBondContact CB-OG 3.41Å; R344-S379 WeakPolarHBondContact CG-OG 3.45Å; F345-S379 PolarHBondContact N-O 2.8Å; V377-S379 PolarHBondContact O-N 3.5Å; S379-H410 WeakPolarHBondContact CA-O 3.47Å; S379-H410 WeakPolarHBondContact CB-ND1 3.4Å; S379-H410 PolarHBondContact OG-ND1 3.21Å
380I96.1Very high93.3Very high1 Ų142 Ų421%0.00523%0.225CC..EExtended strand (participates in β ladder)trans-122139177.5-177.8173.6000110.8F345 V347 I395 F399 I409 H410 G412 L415F345-I380 WeakPolarHBondContact O-CA 3.27Å; V347-I380 HydrophobicContact CG2-CD1 4.23Å; V347-I380 HydrophobicContact CG2-CG1 4.27Å; I380-I395 HydrophobicContact CD1-CG2 4.02Å; I380-F399 HydrophobicContact CB-CD1 3.88Å; I380-F399 HydrophobicContact CB-CD2 4.2Å; I380-F399 HydrophobicContact CB-CE1 3.64Å; I380-F399 HydrophobicContact CB-CE2 3.98Å; I380-F399 HydrophobicContact CB-CG 4.16Å; I380-F399 HydrophobicContact CB-CZ 3.7Å; I380-F399 HydrophobicContact CD1-CB 3.76Å; I380-F399 HydrophobicContact CD1-CD1 4.07Å; I380-F399 HydrophobicContact CD1-CD2 3.94Å; I380-F399 HydrophobicContact CD1-CG 3.67Å; I380-F399 HydrophobicContact CG1-CD2 4.31Å; I380-F399 HydrophobicContact CG1-CE2 4.45Å; I380-F399 HydrophobicContact CG1-CG 4.35Å; I380-F399 HydrophobicContact CG2-CD1 3.92Å; I380-F399 HydrophobicContact CG2-CE1 3.79Å; I380-F399 HydrophobicContact CG2-CZ 4.35Å; I380-I409 HydrophobicContact CG2-CD1 4.39Å; I380-H410 PolarHBondContact N-O 2.94Å; I380-G412 PolarHBondContact O-N 2.85Å; I380-L415 HydrophobicContact CB-CD2 4.41Å; I380-L415 HydrophobicContact CG1-CD2 4.22Å; I380-L415 HydrophobicContact CG2-CD2 3.63Å
381D95Very high93.2Very high2 Ų240.9 Ų40.91%0.01122%0.216CC..EExtended strand (participates in β ladder)trans-141.4168.5170-156.88.3000111.2R344 F345 V347 P413 T414 L415R344-D381 IonicContact CZ-OD2 3.4Å; R344-D381 IonicContact NE-OD2 2.96Å; R344-D381 IonicContact NH2-OD2 2.97Å; R344-D381 PolarHBondContact NH2-OD2 3.16Å; F345-D381 PolarHBondContact O-N 2.99Å; V347-D381 PolarHBondContact N-O 3.13Å; D381-P413 WeakPolarHBondContact OD2-CD 3.42Å; D381-T414 WeakPolarHBondContact OD1-CB 3.24Å; D381-T414 PolarHBondContact OD1-N 3.05Å; D381-T414 VanDerWaalsContact OD1-N 3.08Å; D381-L415 PolarHBondContact OD1-N 2.81Å
382L93.5Very high93.2Very high0 Ų038.3 Ų38.30%020%0.198CC..EExtended strand (participates in β ladder)trans-115.3147.6179.1-60.7174.4000110.7V347 I349 C384 V387 I395 T414 L415V347-L382 HydrophobicContact CB-CD2 4.3Å; I349-L382 HydrophobicContact CG1-CD2 4.37Å; L382-C384 VanDerWaalsContact C-N 3.29Å; L382-C384 PolarHBondContact O-N 3.08Å; L382-V387 HydrophobicContact CD1-CG2 3.85Å; L382-I395 HydrophobicContact CD2-CG2 4.45Å; L382-T414 HydrophobicContact CB-CG2 4.12Å; L382-T414 WeakPolarHBondContact O-CB 3.37Å; L382-T414 VanDerWaalsContact O-CG2 3.31Å; L382-T414 WeakPolarHBondContact O-CG2 3.25Å; L382-T414 PolarHBondContact O-OG1 3.28Å; L382-L415 HydrophobicContact CD1-CB 4.25Å; L382-L415 HydrophobicContact CD1-CD1 3.57Å; L382-L415 HydrophobicContact CD1-CG 4.49Å; L382-L415 HydrophobicContact CG-CB 4.08Å; L382-L415 HydrophobicContact CG-CD1 4.01Å
383N91.1Very high93.1Very high56 Ų5638.7 Ų38.730%0.29920%0.202SC..SBendtrans-75.6-13.7176.970.1-40.3000114.3E346 V347 R348 I349 Q350E346-N383 HydrophobicContact CG-CB 4.22Å; E346-N383 VanDerWaalsContact OE1-CA 3.31Å; E346-N383 WeakPolarHBondContact OE1-CA 3.43Å; V347-N383 PolarHBondContact O-N 3.13Å; V347-N383 PolarHBondContact O-OD1 2.82Å; R348-N383 WeakPolarHBondContact CA-OD1 3.32Å; R348-N383 HydrophobicContact CG-CB 4.4Å; I349-N383 VanDerWaalsContact CD1-OD1 3.26Å; I349-N383 WeakPolarHBondContact CD1-OD1 3.36Å; I349-N383 PolarHBondContact N-OD1 3.43Å; I349-N383 VanDerWaalsContact N-OD1 3.16Å; Q350-N383 PolarHBondContact OE1-ND2 2.81Å
384C88.6Confident93.1Very high38 Ų3839.1 Ų39.126%0.25721%0.209SC..  trans-145.3141.3179.6-177.80000110.5I349 L382 E386 V387 T414I349-C384 HydrophobicContact CD1-CB 3.55Å; L382-C384 VanDerWaalsContact C-N 3.29Å; L382-C384 PolarHBondContact O-N 3.08Å; C384-E386 VanDerWaalsContact C-N 3.31Å; C384-E386 PolarHBondContact SG-N 2.85Å; C384-E386 VanDerWaalsContact SG-N 3.44Å; C384-V387 WeakPolarHBondContact O-CG2 3.33Å; C384-T414 WeakPolarHBondContact O-CG2 3.35Å
385P83Confident93Very high53 Ų5338.9 Ų38.934%0.34421%0.208SC..SBendtrans-75-20.1177.128.9-35.5000113.4V387 T414P385-V387 PolarHBondContact O-N 3.13Å; P385-T414 HydrophobicContact CB-CG2 3.99Å; P385-T414 VanDerWaalsContact N-CG2 3.26Å
386E85Confident92.9Very high163 Ų16336.2 Ų36.276%0.76220%0.195SC*.  trans-90.689.5-177.6-63.3-175.1174.700110.4C384C384-E386 VanDerWaalsContact C-N 3.31Å; C384-E386 PolarHBondContact SG-N 2.85Å; C384-E386 VanDerWaalsContact SG-N 3.44Å
387V88Confident92.7Very high20 Ų2039.1 Ų39.112%0.12122%0.216CC..  trans-129135.2-179.1-1670000109.6I349 L382 C384 P385 R391 C392I349-V387 HydrophobicContact CD1-CB 4.38Å; I349-V387 HydrophobicContact CD1-CG1 4.49Å; I349-V387 HydrophobicContact CD1-CG2 3.18Å; I349-V387 HydrophobicContact CG1-CG1 4.11Å; I349-V387 HydrophobicContact CG1-CG2 3.61Å; I349-V387 HydrophobicContact CG2-CG1 3.77Å; I349-V387 HydrophobicContact CG2-CG2 4.44Å; L382-V387 HydrophobicContact CD1-CG2 3.85Å; C384-V387 WeakPolarHBondContact O-CG2 3.33Å; P385-V387 PolarHBondContact O-N 3.13Å; V387-R391 HydrophobicContact CG1-CB 4.33Å; V387-R391 HydrophobicContact CG1-CG 4.31Å; V387-C392 HydrophobicContact CB-CB 4.48Å; V387-C392 HydrophobicContact CG1-CB 3.97Å
388D91.1Very high92.6Very high103 Ų10342.8 Ų42.855%0.55123%0.233SC*.  trans-57.4137.7168.2175.1-102.4000110.9D390 R391 C392D388-D390 VanDerWaalsContact C-N 3.33Å; D388-D390 PolarHBondContact O-N 3.3Å; D388-D390 WeakPolarHBondContact OD1-CB 3.33Å; D388-D390 PolarHBondContact OD1-N 3.18Å; D388-R391 HydrophobicContact CB-CB 4.13Å; D388-R391 PolarHBondContact O-N 2.8Å; D388-R391 PolarHBondContact OD1-N 3.22Å; D388-R391 VanDerWaalsContact OD1-N 3.08Å; D388-C392 WeakPolarHBondContact O-CB 3.32Å; D388-C392 PolarHBondContact O-N 3.46Å
389V91.6Very high92.4Very high36 Ų3642.8 Ų42.822%0.21823%0.233CC..Hα-helixtrans-64-39.5-172.8-179.40000111.1C392 C393 T425 F426V389-C392 PolarHBondContact O-N 3.34Å; V389-C393 WeakPolarHBondContact O-CB 3.45Å; V389-C393 PolarHBondContact O-N 3.09Å; V389-C393 PolarHBondContact O-SG 2.79Å; V389-T425 HydrophobicContact CG1-CG2 3.97Å; V389-F426 HydrophobicContact CG1-CE2 4.27Å
390D92.9Very high92.3Very high128 Ų12842.9 Ų42.968%0.68423%0.234SC*.Hα-helixtrans-68.4-40.9179.7-66.4-30.9000110.9D388 C393 S394D388-D390 VanDerWaalsContact C-N 3.33Å; D388-D390 PolarHBondContact O-N 3.3Å; D388-D390 WeakPolarHBondContact OD1-CB 3.33Å; D388-D390 PolarHBondContact OD1-N 3.18Å; D390-C393 PolarHBondContact O-N 3.3Å; D390-S394 WeakPolarHBondContact O-CB 3.44Å; D390-S394 PolarHBondContact O-N 3Å
391R93Very high92.1Very high82 Ų8247.1 Ų47.131%0.30926%0.263SS..Hα-helixtrans-61.6-44.6173.3-177.556.3173.41740111.7I349 D351 V387 D388 S394 I395I349-R391 HydrophobicContact CG2-CG 4.17Å; D351-R391 PolarHBondContact O-NH2 3.38Å; V387-R391 HydrophobicContact CG1-CB 4.33Å; V387-R391 HydrophobicContact CG1-CG 4.31Å; D388-R391 HydrophobicContact CB-CB 4.13Å; D388-R391 PolarHBondContact O-N 2.8Å; D388-R391 PolarHBondContact OD1-N 3.22Å; D388-R391 VanDerWaalsContact OD1-N 3.08Å; R391-S394 WeakPolarHBondContact O-CB 3.36Å; R391-S394 PolarHBondContact O-N 3.5Å; R391-I395 HydrophobicContact CG-CD1 4.08Å; R391-I395 WeakPolarHBondContact O-CG1 3.23Å; R391-I395 PolarHBondContact O-N 3.37Å
392C93.4Very high92Very high0 Ų048 Ų480%027%0.271CS..Hα-helixtrans-61.3-47177.1-173.60000111.3V387 D388 V389 S394 I395 V396 F426V387-C392 HydrophobicContact CB-CB 4.48Å; V387-C392 HydrophobicContact CG1-CB 3.97Å; D388-C392 WeakPolarHBondContact O-CB 3.32Å; D388-C392 PolarHBondContact O-N 3.46Å; V389-C392 PolarHBondContact O-N 3.34Å; C392-S394 VanDerWaalsContact C-N 3.3Å; C392-S394 PolarHBondContact O-N 3.46Å; C392-I395 PolarHBondContact O-N 2.95Å; C392-V396 WeakPolarHBondContact O-CB 3.38Å; C392-V396 WeakPolarHBondContact O-CG2 3.29Å; C392-V396 PolarHBondContact O-N 2.92Å; C392-F426 HydrophobicContact CB-CZ 4.03Å
393C94.3Very high91.8Very high27 Ų2748.3 Ų48.318%0.18227%0.272CS..Hα-helixtrans-55.9-44.2174-76.80000112.2V389 D390 S397 F426V389-C393 WeakPolarHBondContact O-CB 3.45Å; V389-C393 PolarHBondContact O-N 3.09Å; V389-C393 PolarHBondContact O-SG 2.79Å; D390-C393 PolarHBondContact O-N 3.3Å; C393-S397 WeakPolarHBondContact O-CB 3.29Å; C393-S397 PolarHBondContact O-N 2.91Å; C393-F426 HydrophobicContact CB-CE1 4.44Å; C393-F426 VanDerWaalsContact SG-CE1 3.51Å; C393-F426 WeakPolarHBondContact SG-CZ 3.29Å
394S94.3Very high91.3Very high46 Ų4647.8 Ų47.832%0.32228%0.28SS..Hα-helixtrans-60.8-49.3178-170.40000112D390 R391 C392 S397 Q398D390-S394 WeakPolarHBondContact O-CB 3.44Å; D390-S394 PolarHBondContact O-N 3Å; R391-S394 WeakPolarHBondContact O-CB 3.36Å; R391-S394 PolarHBondContact O-N 3.5Å; C392-S394 VanDerWaalsContact C-N 3.3Å; C392-S394 PolarHBondContact O-N 3.46Å; S394-S397 PolarHBondContact O-N 3.27Å; S394-Q398 WeakPolarHBondContact O-CB 3.45Å; S394-Q398 VanDerWaalsContact O-CG 3.28Å; S394-Q398 WeakPolarHBondContact O-CG 3.43Å; S394-Q398 PolarHBondContact O-N 2.92Å; S394-Q398 PolarHBondContact OG-NE2 3.1Å
395I94.9Very high91.2Very high1 Ų154.4 Ų54.41%0.00531%0.307CS..Hα-helixtrans-60.7-51.2179.3-70.4167.7000110.7V347 F353 I380 L382 R391 C392 S397 Q398 F399V347-I395 HydrophobicContact CB-CG2 4.27Å; V347-I395 HydrophobicContact CG1-CD1 4.3Å; V347-I395 HydrophobicContact CG1-CG2 3.9Å; V347-I395 HydrophobicContact CG2-CG2 4.29Å; F353-I395 HydrophobicContact CD2-CG2 4.03Å; F353-I395 HydrophobicContact CE2-CG2 4.48Å; I380-I395 HydrophobicContact CD1-CG2 4.02Å; L382-I395 HydrophobicContact CD2-CG2 4.45Å; R391-I395 HydrophobicContact CG-CD1 4.08Å; R391-I395 WeakPolarHBondContact O-CG1 3.23Å; R391-I395 PolarHBondContact O-N 3.37Å; C392-I395 PolarHBondContact O-N 2.95Å; I395-S397 PolarHBondContact O-N 3.03Å; I395-Q398 PolarHBondContact O-N 3Å; I395-F399 WeakPolarHBondContact O-CB 3.43Å; I395-F399 PolarHBondContact O-N 2.88Å
396V94.8Very high91.7Very high1 Ų152.7 Ų52.71%0.00630%0.296CS..Hα-helixtrans-63.3-43-177.8172.50000111C392 Q398 F399 C400 L415 W428 L429C392-V396 WeakPolarHBondContact O-CB 3.38Å; C392-V396 WeakPolarHBondContact O-CG2 3.29Å; C392-V396 PolarHBondContact O-N 2.92Å; V396-Q398 PolarHBondContact O-N 3Å; V396-F399 PolarHBondContact O-N 3.37Å; V396-C400 WeakPolarHBondContact O-CB 3.16Å; V396-C400 PolarHBondContact O-N 3.11Å; V396-C400 PolarHBondContact O-SG 3.05Å; V396-L415 HydrophobicContact CG2-CD1 4.06Å; V396-L415 HydrophobicContact CG2-CD2 4.26Å; V396-W428 HydrophobicContact CG1-CH2 4.05Å; V396-W428 HydrophobicContact CG1-CZ2 4.36Å; V396-L429 HydrophobicContact CG1-CD1 3.6Å; V396-L429 HydrophobicContact CG1-CD2 3.78Å; V396-L429 HydrophobicContact CG1-CG 4.25Å
397S94.3Very high92.1Very high64 Ų6449.8 Ų49.845%0.44829%0.285SS..Hα-helixtrans-63.1-42.7177.4-175.50000112.1C393 S394 I395 S401C393-S397 WeakPolarHBondContact O-CB 3.29Å; C393-S397 PolarHBondContact O-N 2.91Å; S394-S397 PolarHBondContact O-N 3.27Å; I395-S397 PolarHBondContact O-N 3.03Å; S397-S401 WeakPolarHBondContact O-CB 3.49Å; S397-S401 PolarHBondContact O-N 3.3Å; S397-S401 VanDerWaalsContact O-N 3.08Å
398Q94.1Very high92.5Very high77 Ų7749 Ų4936%0.3628%0.28SS..Hα-helixtrans-65.4-42.7177.2-72.4178.418.400111.2F353 S394 I395 V396 S401 A402F353-Q398 HydrophobicContact CD1-CB 3.56Å; F353-Q398 HydrophobicContact CD1-CG 4.49Å; F353-Q398 VanDerWaalsContact CD1-OE1 3.29Å; F353-Q398 HydrophobicContact CE1-CB 3.73Å; F353-Q398 HydrophobicContact CG-CB 4.23Å; S394-Q398 WeakPolarHBondContact O-CB 3.45Å; S394-Q398 VanDerWaalsContact O-CG 3.28Å; S394-Q398 WeakPolarHBondContact O-CG 3.43Å; S394-Q398 PolarHBondContact O-N 2.92Å; S394-Q398 PolarHBondContact OG-NE2 3.1Å; I395-Q398 PolarHBondContact O-N 3Å; V396-Q398 PolarHBondContact O-N 3Å; Q398-S401 PolarHBondContact O-N 3.38Å; Q398-S401 PolarHBondContact O-OG 2.87Å; Q398-A402 PolarHBondContact O-N 3.33Å; Q398-A402 VanDerWaalsContact O-N 3.08Å
399F95.1Very high92.8Very high0 Ų044 Ų440%025%0.254CS..Hα-helixtrans-58.8-51174.6-176.6-94.8000112.1F345 F353 L355 P378 I380 I395 V396 S401 A402 F403 I409F345-F399 HydrophobicContact CB-CE2 4.27Å; F345-F399 AromaticContact CD2-CE2 3.81Å; F345-F399 HydrophobicContact CD2-CE2 3.81Å; F345-F399 HydrophobicContact CD2-CZ 4.14Å; F345-F399 HydrophobicContact CG-CE2 4.3Å; F353-F399 HydrophobicContact CE2-CB 3.89Å; F353-F399 HydrophobicContact CE2-CD2 4Å; F353-F399 HydrophobicContact CE2-CG 4.47Å; F353-F399 VanDerWaalsContact CZ-CA 3.47Å; F353-F399 HydrophobicContact CZ-CB 3.7Å; F353-F399 AromaticContact CZ-CD2 3.92Å; F353-F399 HydrophobicContact CZ-CD2 3.92Å; F353-F399 HydrophobicContact CZ-CG 4.31Å; L355-F399 HydrophobicContact CD1-CD2 4.37Å; L355-F399 HydrophobicContact CD2-CD2 4.05Å; L355-F399 HydrophobicContact CD2-CE2 4.03Å; P378-F399 HydrophobicContact CB-CE1 3.75Å; P378-F399 HydrophobicContact CB-CZ 3.75Å; P378-F399 HydrophobicContact CG-CE1 4.45Å; I380-F399 HydrophobicContact CB-CD1 3.88Å; I380-F399 HydrophobicContact CB-CD2 4.2Å; I380-F399 HydrophobicContact CB-CE1 3.64Å; I380-F399 HydrophobicContact CB-CE2 3.98Å; I380-F399 HydrophobicContact CB-CG 4.16Å; I380-F399 HydrophobicContact CB-CZ 3.7Å; I380-F399 HydrophobicContact CD1-CB 3.76Å; I380-F399 HydrophobicContact CD1-CD1 4.07Å; I380-F399 HydrophobicContact CD1-CD2 3.94Å; I380-F399 HydrophobicContact CD1-CG 3.67Å; I380-F399 HydrophobicContact CG1-CD2 4.31Å; I380-F399 HydrophobicContact CG1-CE2 4.45Å; I380-F399 HydrophobicContact CG1-CG 4.35Å; I380-F399 HydrophobicContact CG2-CD1 3.92Å; I380-F399 HydrophobicContact CG2-CE1 3.79Å; I380-F399 HydrophobicContact CG2-CZ 4.35Å; I395-F399 WeakPolarHBondContact O-CB 3.43Å; I395-F399 PolarHBondContact O-N 2.88Å; V396-F399 PolarHBondContact O-N 3.37Å; F399-S401 PolarHBondContact O-N 3.31Å; F399-A402 WeakPolarHBondContact O-CB 3.36Å; F399-A402 PolarHBondContact O-N 3.14Å; F399-F403 HydrophobicContact CD1-CD2 4.47Å; F399-F403 HydrophobicContact CD1-CE2 4.45Å; F399-F403 HydrophobicContact CD2-CE2 4.07Å; F399-F403 HydrophobicContact CE1-CD2 4.2Å; F399-F403 AromaticContact CE1-CE2 3.98Å; F399-F403 HydrophobicContact CE1-CE2 3.98Å; F399-F403 HydrophobicContact CE2-CD2 4.44Å; F399-F403 AromaticContact CE2-CE2 3.56Å; F399-F403 HydrophobicContact CE2-CE2 3.56Å; F399-F403 HydrophobicContact CE2-CZ 4.3Å; F399-F403 HydrophobicContact CG-CE2 4.49Å; F399-F403 HydrophobicContact CZ-CD2 4.18Å; F399-F403 AromaticContact CZ-CE2 3.5Å; F399-F403 HydrophobicContact CZ-CE2 3.5Å; F399-F403 HydrophobicContact CZ-CZ 4.18Å; F399-F403 WeakPolarHBondContact O-CD2 3.36Å; F399-I409 HydrophobicContact CD1-CD1 4.47Å; F399-I409 HydrophobicContact CE1-CD1 4.35Å
400C93.9Very high93.1Very high3 Ų342.4 Ų42.42%0.0224%0.244CC..Hα-helixtrans-59.7-27.8176.9-70.30000113.4V396 F403 L429 Y433V396-C400 WeakPolarHBondContact O-CB 3.16Å; V396-C400 PolarHBondContact O-N 3.11Å; V396-C400 PolarHBondContact O-SG 3.05Å; C400-F403 VanDerWaalsContact O-O 3.1Å; C400-L429 VanDerWaalsContact SG-CD1 3.54Å; C400-Y433 PolarHBondContact SG-OH 2.96Å
401S92.2Very high93.3Very high90 Ų9036.3 Ų36.363%0.62921%0.211SC*.Hα-helixtrans-80.8-23.4176.974.40000113.9S397 Q398 F399 F403S397-S401 WeakPolarHBondContact O-CB 3.49Å; S397-S401 PolarHBondContact O-N 3.3Å; S397-S401 VanDerWaalsContact O-N 3.08Å; Q398-S401 PolarHBondContact O-N 3.38Å; Q398-S401 PolarHBondContact O-OG 2.87Å; F399-S401 PolarHBondContact O-N 3.31Å; S401-F403 VanDerWaalsContact C-N 3.32Å
402A92.2Very high93.4Very high20 Ų2032.4 Ų32.417%0.16520%0.197CC..Hα-helixtrans-75.4-24.9179.700000112.5L355 Q398 F399L355-A402 HydrophobicContact CD1-CB 3.58Å; Q398-A402 PolarHBondContact O-N 3.33Å; Q398-A402 VanDerWaalsContact O-N 3.08Å; F399-A402 WeakPolarHBondContact O-CB 3.36Å; F399-A402 PolarHBondContact O-N 3.14Å
403F90.3Very high93.2Very high7 Ų734.2 Ų34.23%0.03121%0.208CC..SBendtrans-95.4137.4170.8-65-90.5000109.4F345 L355 L362 P378 F399 C400 S401 V406F345-F403 HydrophobicContact CD2-CZ 4.45Å; F345-F403 AromaticContact CE2-CZ 3.79Å; F345-F403 HydrophobicContact CE2-CZ 3.79Å; F345-F403 HydrophobicContact CZ-CZ 4.47Å; L355-F403 HydrophobicContact CD1-CE2 3.74Å; L355-F403 HydrophobicContact CD1-CZ 4.19Å; L362-F403 HydrophobicContact CB-CE1 4.5Å; L362-F403 HydrophobicContact CD1-CD1 4.28Å; L362-F403 HydrophobicContact CD1-CE1 3.9Å; L362-F403 HydrophobicContact CD1-CE2 4.39Å; L362-F403 HydrophobicContact CD1-CZ 3.95Å; L362-F403 HydrophobicContact CD2-CE1 3.86Å; L362-F403 HydrophobicContact CD2-CZ 4.27Å; L362-F403 HydrophobicContact CG-CE1 4.31Å; P378-F403 HydrophobicContact CB-CD1 3.74Å; P378-F403 HydrophobicContact CB-CD2 3.69Å; P378-F403 HydrophobicContact CB-CE1 3.7Å; P378-F403 HydrophobicContact CB-CE2 3.68Å; P378-F403 HydrophobicContact CB-CG 3.74Å; P378-F403 HydrophobicContact CB-CZ 3.69Å; P378-F403 HydrophobicContact CG-CB 4.39Å; P378-F403 HydrophobicContact CG-CD1 4.19Å; P378-F403 HydrophobicContact CG-CD2 4.25Å; P378-F403 HydrophobicContact CG-CG 4.01Å; F399-F403 HydrophobicContact CD1-CD2 4.47Å; F399-F403 HydrophobicContact CD1-CE2 4.45Å; F399-F403 HydrophobicContact CD2-CE2 4.07Å; F399-F403 HydrophobicContact CE1-CD2 4.2Å; F399-F403 AromaticContact CE1-CE2 3.98Å; F399-F403 HydrophobicContact CE1-CE2 3.98Å; F399-F403 HydrophobicContact CE2-CD2 4.44Å; F399-F403 AromaticContact CE2-CE2 3.56Å; F399-F403 HydrophobicContact CE2-CE2 3.56Å; F399-F403 HydrophobicContact CE2-CZ 4.3Å; F399-F403 HydrophobicContact CG-CE2 4.49Å; F399-F403 HydrophobicContact CZ-CD2 4.18Å; F399-F403 AromaticContact CZ-CE2 3.5Å; F399-F403 HydrophobicContact CZ-CE2 3.5Å; F399-F403 HydrophobicContact CZ-CZ 4.18Å; F399-F403 WeakPolarHBondContact O-CD2 3.36Å; C400-F403 VanDerWaalsContact O-O 3.1Å; S401-F403 VanDerWaalsContact C-N 3.32Å; F403-V406 HydrophobicContact CB-CG1 4.48Å; F403-V406 HydrophobicContact CB-CG2 4.13Å
404G80.8Confident93.1Very high45 Ų4534.4 Ų34.446%0.46421%0.209SC..  trans-72.9-137.5178.200000112.9V406G404-V406 VanDerWaalsContact C-N 3.28Å; G404-V406 PolarHBondContact O-N 2.88Å
405E85.4Confident93.1Very high177 Ų17732.2 Ų32.283%0.82719%0.194SC*.SBendtrans-74.475.4-179.8-63.9-177173.600111.8
406V93.7Very high92.9Very high17 Ų1732.2 Ų32.210%0.10319%0.194CC..  trans-102.8134.6171.3-610000110.4P378 F403 G404 Y433P378-V406 HydrophobicContact CG-CG2 3.86Å; F403-V406 HydrophobicContact CB-CG1 4.48Å; F403-V406 HydrophobicContact CB-CG2 4.13Å; G404-V406 VanDerWaalsContact C-N 3.28Å; G404-V406 PolarHBondContact O-N 2.88Å; V406-Y433 HydrophobicContact CG2-CE1 3.96Å; V406-Y433 WeakPolarHBondContact O-CD1 3.38Å; V406-Y433 WeakPolarHBondContact O-CE1 3.3Å
407N93.7Very high92.6Very high101 Ų10135.2 Ų35.254%0.5421%0.208SC..SBendtrans-86.6-17.1-175.6-69.2-38.7000113.9S434N407-S434 PolarHBondContact O-N 3.3Å; N407-S434 PolarHBondContact O-OG 3.27Å; N407-S434 VanDerWaalsContact O-OG 3.12Å
408C97.1Very high92.3Very high3 Ų332.4 Ų32.42%0.0219%0.188CC..EExtended strand (participates in β ladder)trans-124.9154.5-176.8-64.30000110.9Q375 V377 P378 C435 F437Q375-C408 VanDerWaalsContact CD-SG 3.52Å; Q375-C408 PolarHBondContact NE2-SG 3.02Å; V377-C408 HydrophobicContact CG1-CB 4.14Å; V377-C408 HydrophobicContact CG2-CB 3.89Å; P378-C408 WeakPolarHBondContact CD-O 3.49Å; C408-C435 VanDerWaalsContact CA-O 3.24Å; C408-C435 WeakPolarHBondContact CA-O 3.39Å; C408-C435 VanDerWaalsContact SG-CB 3.57Å; C408-F437 HydrophobicContact CB-CE2 4.24Å
409I97.6Very high92.2Very high0 Ų028.8 Ų28.80%017%0.171CC..EExtended strand (participates in β ladder)trans-137.1153169.2-168.7168.2000109.3P378 I380 F399 L429 Y433 C435 V436 F437P378-I409 HydrophobicContact CG-CG1 4.49Å; P378-I409 WeakPolarHBondContact O-CG1 3.47Å; I380-I409 HydrophobicContact CG2-CD1 4.39Å; F399-I409 HydrophobicContact CD1-CD1 4.47Å; F399-I409 HydrophobicContact CE1-CD1 4.35Å; I409-L429 HydrophobicContact CD1-CD1 4.31Å; I409-Y433 HydrophobicContact CB-CD1 4.23Å; I409-Y433 HydrophobicContact CB-CD2 3.86Å; I409-Y433 HydrophobicContact CB-CE1 4.22Å; I409-Y433 HydrophobicContact CB-CE2 3.83Å; I409-Y433 HydrophobicContact CB-CG 4.05Å; I409-Y433 HydrophobicContact CD1-CD2 4.5Å; I409-Y433 HydrophobicContact CD1-CE2 3.76Å; I409-Y433 HydrophobicContact CG1-CE2 4.39Å; I409-Y433 HydrophobicContact CG2-CD1 4.41Å; I409-Y433 HydrophobicContact CG2-CD2 3.35Å; I409-Y433 HydrophobicContact CG2-CE2 3.73Å; I409-Y433 HydrophobicContact CG2-CG 3.73Å; I409-C435 PolarHBondContact N-O 2.95Å; I409-V436 HydrophobicContact CG2-CB 4.38Å; I409-V436 HydrophobicContact CG2-CG1 4.07Å; I409-V436 HydrophobicContact CG2-CG2 4.03Å; I409-V436 CarbonylContact O-C 3.51Å; I409-V436 WeakPolarHBondContact O-CA 3.48Å; I409-F437 PolarHBondContact O-N 2.9Å
410H98Very high91.9Very high1 Ų131 Ų311%0.00518%0.183CC..EExtended strand (participates in β ladder)trans-115.4133.2168.9172.2-121.8000111.1L342 V377 P378 S379 I380 F437 S439L342-H410 HydrophobicContact CD2-CB 3.94Å; L342-H410 HydrophobicContact CG-CB 4.38Å; V377-H410 HydrophobicContact CG1-CB 3.92Å; P378-H410 PolarHBondContact O-N 3.28Å; S379-H410 WeakPolarHBondContact CA-O 3.47Å; S379-H410 WeakPolarHBondContact CB-ND1 3.4Å; S379-H410 PolarHBondContact OG-ND1 3.21Å; I380-H410 PolarHBondContact N-O 2.94Å; H410-F437 CarbonylContact C-O 3.59Å; H410-F437 WeakPolarHBondContact CA-O 3.32Å; H410-F437 HydrophobicContact CB-CB 3.8Å; H410-F437 PolarHBondContact CD2-O 3.41Å; H410-S439 PolarHBondContact CE1-OG 2.97Å; H410-S439 PolarHBondContact NE2-OG 2.8Å
411I96.4Very high91.6Very high0 Ų039.3 Ų39.30%021%0.214CC..EExtended strand (participates in β ladder)trans-110.1117.6-179.9-62.2174.4000107.4L415 L419 L429 L430 V436 F437 W438 S439I411-L415 HydrophobicContact CG2-CB 4.18Å; I411-L415 HydrophobicContact CG2-CD2 4.09Å; I411-L415 HydrophobicContact CG2-CG 3.98Å; I411-L419 HydrophobicContact CD1-CD1 3.68Å; I411-L419 HydrophobicContact CG1-CD1 4.38Å; I411-L419 HydrophobicContact CG2-CD1 3.79Å; I411-L429 HydrophobicContact CD1-CD2 4.11Å; I411-L430 HydrophobicContact CD1-CD2 4Å; I411-V436 HydrophobicContact CD1-CG1 3.45Å; I411-V436 VanDerWaalsContact CD1-CG1 3.45Å; I411-V436 HydrophobicContact CG1-CG1 4.06Å; I411-F437 PolarHBondContact N-O 3.31Å; I411-W438 HydrophobicContact CB-CE3 4.33Å; I411-W438 HydrophobicContact CD1-CE3 3.77Å; I411-W438 HydrophobicContact CD1-CZ3 3.7Å; I411-W438 HydrophobicContact CG2-CE3 4.35Å; I411-W438 HydrophobicContact CG2-CZ3 4.39Å; I411-S439 PolarHBondContact O-N 3.22Å
412G94.4Very high91.4Very high0 Ų037.2 Ų37.20%020%0.195CC..  trans-70.2167176.700000113.3I380 T414 G416I380-G412 PolarHBondContact O-N 2.85Å; G412-T414 PolarHBondContact O-N 3.21Å; G412-G416 PolarHBondContact O-N 3.25Å
413P90.8Very high91.3Very high38 Ų3838 Ų3825%0.24720%0.197CC..Hα-helixtrans-56.7-48.1-173.221.2-34.7000114D381 G416 Q417 A441D381-P413 WeakPolarHBondContact OD2-CD 3.42Å; P413-G416 PolarHBondContact O-N 3.47Å; P413-Q417 PolarHBondContact O-N 2.92Å; P413-Q417 VanDerWaalsContact O-N 3.08Å; P413-A441 HydrophobicContact CB-CB 3.38Å; P413-A441 WeakPolarHBondContact O-CB 3.4Å
414T91.5Very high91.4Very high32 Ų3242.5 Ų42.520%0.19623%0.229CC..Hα-helixtrans-68.4-45.5-174.7-51.90000111D381 L382 C384 P385 G412 G416 Q417 C418D381-T414 WeakPolarHBondContact OD1-CB 3.24Å; D381-T414 PolarHBondContact OD1-N 3.05Å; D381-T414 VanDerWaalsContact OD1-N 3.08Å; L382-T414 HydrophobicContact CB-CG2 4.12Å; L382-T414 WeakPolarHBondContact O-CB 3.37Å; L382-T414 VanDerWaalsContact O-CG2 3.31Å; L382-T414 WeakPolarHBondContact O-CG2 3.25Å; L382-T414 PolarHBondContact O-OG1 3.28Å; C384-T414 WeakPolarHBondContact O-CG2 3.35Å; P385-T414 HydrophobicContact CB-CG2 3.99Å; P385-T414 VanDerWaalsContact N-CG2 3.26Å; G412-T414 PolarHBondContact O-N 3.21Å; T414-G416 VanDerWaalsContact C-N 3.33Å; T414-G416 PolarHBondContact O-N 2.87Å; T414-Q417 PolarHBondContact O-N 3.33Å; T414-C418 PolarHBondContact O-N 3.29Å
415L93.2Very high91.9Very high0 Ų043.2 Ų43.20%022%0.224CC..Hα-helixtrans-61.4-44.3173.6179.560.3000110.8I380 D381 L382 V396 I411 Q417 C418 L419I380-L415 HydrophobicContact CB-CD2 4.41Å; I380-L415 HydrophobicContact CG1-CD2 4.22Å; I380-L415 HydrophobicContact CG2-CD2 3.63Å; D381-L415 PolarHBondContact OD1-N 2.81Å; L382-L415 HydrophobicContact CD1-CB 4.25Å; L382-L415 HydrophobicContact CD1-CD1 3.57Å; L382-L415 HydrophobicContact CD1-CG 4.49Å; L382-L415 HydrophobicContact CG-CB 4.08Å; L382-L415 HydrophobicContact CG-CD1 4.01Å; V396-L415 HydrophobicContact CG2-CD1 4.06Å; V396-L415 HydrophobicContact CG2-CD2 4.26Å; I411-L415 HydrophobicContact CG2-CB 4.18Å; I411-L415 HydrophobicContact CG2-CD2 4.09Å; I411-L415 HydrophobicContact CG2-CG 3.98Å; L415-Q417 VanDerWaalsContact C-N 3.3Å; L415-Q417 PolarHBondContact O-N 3.11Å; L415-C418 WeakPolarHBondContact O-CA 3.4Å; L415-C418 WeakPolarHBondContact O-CB 3.21Å; L415-C418 PolarHBondContact O-N 3.34Å; L415-L419 HydrophobicContact CD1-CD1 4.32Å; L415-L419 HydrophobicContact CD1-CD2 4.02Å; L415-L419 HydrophobicContact CD1-CG 3.95Å; L415-L419 HydrophobicContact CD2-CD1 4.43Å; L415-L419 HydrophobicContact CG-CD1 3.94Å; L415-L419 HydrophobicContact CG-CG 4.01Å; L415-L419 VanDerWaalsContact O-CG 3.31Å; L415-L419 WeakPolarHBondContact O-CG 3.5Å; L415-L419 PolarHBondContact O-N 2.88Å
416G91.6Very high92.3Very high1 Ų134.8 Ų34.81%0.0119%0.185CC..Hα-helixtrans-53.2-46178.500000112.4G412 P413 T414 C418 L419 L420 W438G412-G416 PolarHBondContact O-N 3.25Å; P413-G416 PolarHBondContact O-N 3.47Å; T414-G416 VanDerWaalsContact C-N 3.33Å; T414-G416 PolarHBondContact O-N 2.87Å; G416-C418 VanDerWaalsContact C-N 3.34Å; G416-C418 PolarHBondContact O-N 2.77Å; G416-L419 PolarHBondContact O-N 2.77Å; G416-L420 WeakPolarHBondContact O-CB 3.46Å; G416-L420 WeakPolarHBondContact O-CG 3.18Å; G416-L420 PolarHBondContact O-N 3.29Å; G416-W438 WeakPolarHBondContact O-CZ2 3.34Å
417Q88.2Confident92.2Very high63 Ų6337.3 Ų37.329%0.29420%0.203SC..Hα-helixtrans-60.6-41.1175.7-69.7-176.3-11.200112.9P413 T414 L415 R421 A441P413-Q417 PolarHBondContact O-N 2.92Å; P413-Q417 VanDerWaalsContact O-N 3.08Å; T414-Q417 PolarHBondContact O-N 3.33Å; L415-Q417 VanDerWaalsContact C-N 3.3Å; L415-Q417 PolarHBondContact O-N 3.11Å; Q417-R421 WeakPolarHBondContact O-CG 3.49Å; Q417-R421 PolarHBondContact O-N 3.13Å; Q417-A441 HydrophobicContact CG-CB 3.64Å
418C88.8Confident92.2Very high5 Ų537.1 Ų37.13%0.03420%0.195CC..Hα-helixtrans-63.6-43.2177-175.30000111.8T414 L415 G416 R421 N422T414-C418 PolarHBondContact O-N 3.29Å; L415-C418 WeakPolarHBondContact O-CA 3.4Å; L415-C418 WeakPolarHBondContact O-CB 3.21Å; L415-C418 PolarHBondContact O-N 3.34Å; G416-C418 VanDerWaalsContact C-N 3.34Å; G416-C418 PolarHBondContact O-N 2.77Å; C418-R421 PolarHBondContact O-N 3.39Å; C418-N422 PolarHBondContact O-N 3Å; C418-N422 PolarHBondContact O-ND2 3.4Å; C418-N422 VanDerWaalsContact O-ND2 3.1Å
419L91.2Very high92.1Very high2 Ų237 Ų371%0.0119%0.194CC..Hα-helixtrans-68.1-39.9179-62-176.6000112.1I411 L415 G416 R421 N422 L423 F426 L429 W438I411-L419 HydrophobicContact CD1-CD1 3.68Å; I411-L419 HydrophobicContact CG1-CD1 4.38Å; I411-L419 HydrophobicContact CG2-CD1 3.79Å; L415-L419 HydrophobicContact CD1-CD1 4.32Å; L415-L419 HydrophobicContact CD1-CD2 4.02Å; L415-L419 HydrophobicContact CD1-CG 3.95Å; L415-L419 HydrophobicContact CD2-CD1 4.43Å; L415-L419 HydrophobicContact CG-CD1 3.94Å; L415-L419 HydrophobicContact CG-CG 4.01Å; L415-L419 VanDerWaalsContact O-CG 3.31Å; L415-L419 WeakPolarHBondContact O-CG 3.5Å; L415-L419 PolarHBondContact O-N 2.88Å; G416-L419 PolarHBondContact O-N 2.77Å; L419-R421 VanDerWaalsContact C-N 3.28Å; L419-R421 PolarHBondContact O-N 2.87Å; L419-N422 CarbonylContact O-C 3.48Å; L419-N422 PolarHBondContact O-N 3.31Å; L419-L423 WeakPolarHBondContact O-CA 3.28Å; L419-L423 PolarHBondContact O-N 3.46Å; L419-F426 HydrophobicContact CD2-CB 3.87Å; L419-F426 HydrophobicContact CD2-CD1 3.32Å; L419-F426 HydrophobicContact CD2-CD2 3.38Å; L419-F426 HydrophobicContact CD2-CE1 3.53Å; L419-F426 HydrophobicContact CD2-CE2 3.61Å; L419-F426 HydrophobicContact CD2-CG 3.24Å; L419-F426 HydrophobicContact CD2-CZ 3.68Å; L419-F426 HydrophobicContact CG-CG 4.47Å; L419-L429 HydrophobicContact CD1-CD2 3.88Å; L419-W438 HydrophobicContact CB-CH2 3.77Å; L419-W438 HydrophobicContact CD1-CH2 4.17Å; L419-W438 HydrophobicContact CD1-CZ3 4.28Å
420L88.6Confident91.9Very high46 Ų4637.4 Ų37.424%0.24120%0.196CC..Hα-helixtrans-59.7-38.2177.1-82.8163.3000112.3G416 N422 L423 W438 A453 L457G416-L420 WeakPolarHBondContact O-CB 3.46Å; G416-L420 WeakPolarHBondContact O-CG 3.18Å; G416-L420 PolarHBondContact O-N 3.29Å; L420-N422 PolarHBondContact O-N 3.5Å; L420-L423 HydrophobicContact CD2-CD1 4.2Å; L420-L423 HydrophobicContact CD2-CD2 4.41Å; L420-W438 HydrophobicContact CD1-CZ2 3.78Å; L420-W438 HydrophobicContact CD2-CZ2 4.28Å; L420-W438 HydrophobicContact CG-CH2 4.11Å; L420-W438 HydrophobicContact CG-CZ2 3.58Å; L420-A453 WeakPolarHBondContact CD2-O 3.47Å; L420-L457 HydrophobicContact CD2-CD2 3.86Å; L420-L457 HydrophobicContact CD2-CG 4.23Å
421R87.2Confident91.8Very high178 Ų17841.3 Ų41.367%0.67223%0.229SC*.Hα-helixtrans-67.2-22.7175.4-68174.8-177.1-179.82113Q417 C418 L419Q417-R421 WeakPolarHBondContact O-CG 3.49Å; Q417-R421 PolarHBondContact O-N 3.13Å; C418-R421 PolarHBondContact O-N 3.39Å; L419-R421 VanDerWaalsContact C-N 3.28Å; L419-R421 PolarHBondContact O-N 2.87Å
422N90Very high91.7Very high45 Ų4548 Ų4824%0.24125%0.254CS..THydrogen-bonded Turntrans-13034.2-171.4-62.8-75.8000112.8C418 L419 L420 S424 T425 F426C418-N422 PolarHBondContact O-N 3Å; C418-N422 PolarHBondContact O-ND2 3.4Å; C418-N422 VanDerWaalsContact O-ND2 3.1Å; L419-N422 CarbonylContact O-C 3.48Å; L419-N422 PolarHBondContact O-N 3.31Å; L420-N422 PolarHBondContact O-N 3.5Å; N422-S424 PolarHBondContact O-N 3.44Å; N422-S424 VanDerWaalsContact O-N 3.09Å; N422-T425 WeakPolarHBondContact O-CB 3.23Å; N422-T425 PolarHBondContact O-N 3.28Å; N422-F426 HydrophobicContact CB-CD2 3.91Å; N422-F426 HydrophobicContact CB-CE2 3.9Å; N422-F426 WeakPolarHBondContact O-CD2 3.24Å; N422-F426 PolarHBondContact O-N 2.82Å
423L90.1Very high91.7Very high38 Ų3848.4 Ų48.420%0.19926%0.255CS..Hα-helixtrans-54.3-35.4-171.5-77.5172000114L419 L420 T425 F426 S427 L430 V456 L457L419-L423 WeakPolarHBondContact O-CA 3.28Å; L419-L423 PolarHBondContact O-N 3.46Å; L420-L423 HydrophobicContact CD2-CD1 4.2Å; L420-L423 HydrophobicContact CD2-CD2 4.41Å; L423-T425 VanDerWaalsContact C-N 3.28Å; L423-T425 PolarHBondContact O-N 2.83Å; L423-F426 CarbonylContact O-C 3.19Å; L423-F426 PolarHBondContact O-N 2.76Å; L423-S427 PolarHBondContact O-N 3.06Å; L423-L430 HydrophobicContact CD2-CD1 4.11Å; L423-V456 HydrophobicContact CD1-CB 4.34Å; L423-V456 HydrophobicContact CD1-CG1 3.7Å; L423-L457 HydrophobicContact CD2-CD2 4.13Å
424S91.1Very high91.9Very high100 Ų10050.7 Ų50.770%0.69927%0.272SS*.Hα-helixtrans-58.2-43.1176.951.40000111.8N422 S427N422-S424 PolarHBondContact O-N 3.44Å; N422-S424 VanDerWaalsContact O-N 3.09Å; S424-S427 PolarHBondContact O-OG 3.32Å
425T92.1Very high92.2Very high60 Ų6050.2 Ų50.237%0.36827%0.27SS..Hα-helixtrans-70.9-33.7-178.5-510000111.7V389 N422 L423 W428V389-T425 HydrophobicContact CG1-CG2 3.97Å; N422-T425 WeakPolarHBondContact O-CB 3.23Å; N422-T425 PolarHBondContact O-N 3.28Å; L423-T425 VanDerWaalsContact C-N 3.28Å; L423-T425 PolarHBondContact O-N 2.83Å; T425-W428 PolarHBondContact O-NE1 2.81Å; T425-W428 VanDerWaalsContact O-NE1 3.14Å
426F92.7Very high92.4Very high1 Ų150.2 Ų50.20%0.00427%0.27CS..Hα-helixtrans-1018.9-177.6-66.2-80.4000114.3V389 C392 C393 L419 N422 L423 W428 L429 L430V389-F426 HydrophobicContact CG1-CE2 4.27Å; C392-F426 HydrophobicContact CB-CZ 4.03Å; C393-F426 HydrophobicContact CB-CE1 4.44Å; C393-F426 VanDerWaalsContact SG-CE1 3.51Å; C393-F426 WeakPolarHBondContact SG-CZ 3.29Å; L419-F426 HydrophobicContact CD2-CB 3.87Å; L419-F426 HydrophobicContact CD2-CD1 3.32Å; L419-F426 HydrophobicContact CD2-CD2 3.38Å; L419-F426 HydrophobicContact CD2-CE1 3.53Å; L419-F426 HydrophobicContact CD2-CE2 3.61Å; L419-F426 HydrophobicContact CD2-CG 3.24Å; L419-F426 HydrophobicContact CD2-CZ 3.68Å; L419-F426 HydrophobicContact CG-CG 4.47Å; N422-F426 HydrophobicContact CB-CD2 3.91Å; N422-F426 HydrophobicContact CB-CE2 3.9Å; N422-F426 WeakPolarHBondContact O-CD2 3.24Å; N422-F426 PolarHBondContact O-N 2.82Å; L423-F426 CarbonylContact O-C 3.19Å; L423-F426 PolarHBondContact O-N 2.76Å; F426-W428 PolarHBondContact O-N 2.98Å; F426-W428 VanDerWaalsContact O-N 3.15Å; F426-L429 VanDerWaalsContact O-CB 3.29Å; F426-L429 WeakPolarHBondContact O-CB 3.48Å; F426-L429 PolarHBondContact O-N 3.3Å; F426-L430 PolarHBondContact O-N 3.5Å
427S92.4Very high92.7Very high69 Ų6950.1 Ų50.148%0.48327%0.27SS..Hα-helixtrans-53.4-36176.656.90000112.7L423 S424 L429 L430 A431L423-S427 PolarHBondContact O-N 3.06Å; S424-S427 PolarHBondContact O-OG 3.32Å; S427-L429 VanDerWaalsContact C-N 3.31Å; S427-L429 PolarHBondContact O-N 3.16Å; S427-L430 PolarHBondContact O-N 2.96Å; S427-A431 WeakPolarHBondContact O-CB 3.34Å; S427-A431 PolarHBondContact O-N 3.15Å
428W94.4Very high93Very high98 Ų9847.3 Ų47.337%0.37126%0.256SS..Hα-helixtrans-61.6-35.7175.368.9-94.8000113V396 T425 F426 R432V396-W428 HydrophobicContact CG1-CH2 4.05Å; V396-W428 HydrophobicContact CG1-CZ2 4.36Å; T425-W428 PolarHBondContact O-NE1 2.81Å; T425-W428 VanDerWaalsContact O-NE1 3.14Å; F426-W428 PolarHBondContact O-N 2.98Å; F426-W428 VanDerWaalsContact O-N 3.15Å; W428-R432 WeakPolarHBondContact O-CB 3.5Å; W428-R432 PolarHBondContact O-N 2.84Å
429L94.8Very high93.1Very high1 Ų147.7 Ų47.71%0.00526%0.259CS..Hα-helixtrans-66.8-47.4179.9178.470.2000109.7V396 C400 I409 I411 L419 F426 S427 A431 R432 Y433V396-L429 HydrophobicContact CG1-CD1 3.6Å; V396-L429 HydrophobicContact CG1-CD2 3.78Å; V396-L429 HydrophobicContact CG1-CG 4.25Å; C400-L429 VanDerWaalsContact SG-CD1 3.54Å; I409-L429 HydrophobicContact CD1-CD1 4.31Å; I411-L429 HydrophobicContact CD1-CD2 4.11Å; L419-L429 HydrophobicContact CD1-CD2 3.88Å; F426-L429 VanDerWaalsContact O-CB 3.29Å; F426-L429 WeakPolarHBondContact O-CB 3.48Å; F426-L429 PolarHBondContact O-N 3.3Å; S427-L429 VanDerWaalsContact C-N 3.31Å; S427-L429 PolarHBondContact O-N 3.16Å; L429-A431 VanDerWaalsContact C-N 3.3Å; L429-A431 PolarHBondContact O-N 3.39Å; L429-R432 WeakPolarHBondContact O-CB 3.41Å; L429-R432 PolarHBondContact O-N 3.23Å; L429-Y433 HydrophobicContact CD1-CE2 3.95Å; L429-Y433 WeakPolarHBondContact O-CD2 3.47Å
430L93.7Very high92.8Very high7 Ų749 Ų494%0.03727%0.267CS..Hα-helixtrans-69.5-30-179.1-53-177.1000112.2I411 L423 F426 S427 V436 W438 P458 N460I411-L430 HydrophobicContact CD1-CD2 4Å; L423-L430 HydrophobicContact CD2-CD1 4.11Å; F426-L430 PolarHBondContact O-N 3.5Å; S427-L430 PolarHBondContact O-N 2.96Å; L430-V436 HydrophobicContact CD2-CG1 4.01Å; L430-V436 HydrophobicContact CD2-CG2 4.3Å; L430-W438 HydrophobicContact CD2-CZ3 3.97Å; L430-P458 HydrophobicContact CB-CG 4.42Å; L430-P458 HydrophobicContact CD1-CG 4.15Å; L430-N460 PolarHBondContact O-ND2 3.18Å
431A94.3Very high91.7Very high84 Ų8448 Ų4869%0.69427%0.265SS*.Hα-helixtrans-78.8-22.3175.800000113.6S427 L429 Y433S427-A431 WeakPolarHBondContact O-CB 3.34Å; S427-A431 PolarHBondContact O-N 3.15Å; L429-A431 VanDerWaalsContact C-N 3.3Å; L429-A431 PolarHBondContact O-N 3.39Å; A431-Y433 VanDerWaalsContact C-N 3.35Å
432R94.3Very high90.3Very high140 Ų14041.3 Ų41.353%0.52825%0.252SS..Hα-helixtrans-68-32.3-178.7179178.3176.2105.9-1.6113W428 L429W428-R432 WeakPolarHBondContact O-CB 3.5Å; W428-R432 PolarHBondContact O-N 2.84Å; L429-R432 WeakPolarHBondContact O-CB 3.41Å; L429-R432 PolarHBondContact O-N 3.23Å
433Y95.4Very high88.6Confident8 Ų847.6 Ų47.63%0.03129%0.285CS..  trans-110.3142.2-171.5-63-76.4000112C400 V406 I409 L429 A431 C435 N460C400-Y433 PolarHBondContact SG-OH 2.96Å; V406-Y433 HydrophobicContact CG2-CE1 3.96Å; V406-Y433 WeakPolarHBondContact O-CD1 3.38Å; V406-Y433 WeakPolarHBondContact O-CE1 3.3Å; I409-Y433 HydrophobicContact CB-CD1 4.23Å; I409-Y433 HydrophobicContact CB-CD2 3.86Å; I409-Y433 HydrophobicContact CB-CE1 4.22Å; I409-Y433 HydrophobicContact CB-CE2 3.83Å; I409-Y433 HydrophobicContact CB-CG 4.05Å; I409-Y433 HydrophobicContact CD1-CD2 4.5Å; I409-Y433 HydrophobicContact CD1-CE2 3.76Å; I409-Y433 HydrophobicContact CG1-CE2 4.39Å; I409-Y433 HydrophobicContact CG2-CD1 4.41Å; I409-Y433 HydrophobicContact CG2-CD2 3.35Å; I409-Y433 HydrophobicContact CG2-CE2 3.73Å; I409-Y433 HydrophobicContact CG2-CG 3.73Å; L429-Y433 HydrophobicContact CD1-CE2 3.95Å; L429-Y433 WeakPolarHBondContact O-CD2 3.47Å; A431-Y433 VanDerWaalsContact C-N 3.35Å; Y433-C435 VanDerWaalsContact C-N 3.26Å; Y433-C435 PolarHBondContact O-N 2.88Å; Y433-N460 PolarHBondContact O-ND2 2.92Å
434S95.4Very high87.1Confident86 Ų8647.2 Ų47.260%0.60129%0.291SS*.SBendtrans-73.4-21.9178.465.70000112.8N407 N460N407-S434 PolarHBondContact O-N 3.3Å; N407-S434 PolarHBondContact O-OG 3.27Å; N407-S434 VanDerWaalsContact O-OG 3.12Å; S434-N460 WeakPolarHBondContact O-CB 3.15Å
435C96.9Very high85.8Confident22 Ų2242.6 Ų42.615%0.14926%0.259CS..EExtended strand (participates in β ladder)trans-144.8133.1171.5175.70000110.2C408 I409 Y433 N460C408-C435 VanDerWaalsContact CA-O 3.24Å; C408-C435 WeakPolarHBondContact CA-O 3.39Å; C408-C435 VanDerWaalsContact SG-CB 3.57Å; I409-C435 PolarHBondContact N-O 2.95Å; Y433-C435 VanDerWaalsContact C-N 3.26Å; Y433-C435 PolarHBondContact O-N 2.88Å; C435-N460 WeakPolarHBondContact CA-O 3.31Å
436V97.2Very high84.5Confident0 Ų040 Ų400%024%0.243CC..EExtended strand (participates in β ladder)trans-118.4106.3177.4179.30000107.8I409 I411 L430 W438 N460 C461 V462I409-V436 HydrophobicContact CG2-CB 4.38Å; I409-V436 HydrophobicContact CG2-CG1 4.07Å; I409-V436 HydrophobicContact CG2-CG2 4.03Å; I409-V436 CarbonylContact O-C 3.51Å; I409-V436 WeakPolarHBondContact O-CA 3.48Å; I411-V436 HydrophobicContact CD1-CG1 3.45Å; I411-V436 VanDerWaalsContact CD1-CG1 3.45Å; I411-V436 HydrophobicContact CG1-CG1 4.06Å; L430-V436 HydrophobicContact CD2-CG1 4.01Å; L430-V436 HydrophobicContact CD2-CG2 4.3Å; V436-W438 HydrophobicContact CG1-CE3 4.31Å; V436-N460 PolarHBondContact N-O 3.01Å; V436-C461 CarbonylContact O-C 3.5Å; V436-C461 VanDerWaalsContact O-CA 3.24Å; V436-C461 WeakPolarHBondContact O-CA 3.29Å; V436-V462 PolarHBondContact O-N 3.34Å
437F97.7Very high82.9Confident0 Ų043 Ų430%026%0.259CS..EExtended strand (participates in β ladder)trans-71.8135.5169.8-66.7-87.1000109.2I308 H340 V377 C408 I409 H410 I411 V462 I464I308-F437 HydrophobicContact CD1-CE1 3.81Å; I308-F437 HydrophobicContact CD1-CZ 4Å; I308-F437 HydrophobicContact CG2-CE1 4.08Å; I308-F437 HydrophobicContact CG2-CZ 4.26Å; H340-F437 AromaticContact CD2-CZ 3.77Å; V377-F437 HydrophobicContact CG1-CD2 3.81Å; V377-F437 HydrophobicContact CG1-CE2 4.17Å; V377-F437 HydrophobicContact CG2-CD2 4.49Å; V377-F437 HydrophobicContact CG2-CE2 4.02Å; C408-F437 HydrophobicContact CB-CE2 4.24Å; I409-F437 PolarHBondContact O-N 2.9Å; H410-F437 CarbonylContact C-O 3.59Å; H410-F437 WeakPolarHBondContact CA-O 3.32Å; H410-F437 HydrophobicContact CB-CB 3.8Å; H410-F437 PolarHBondContact CD2-O 3.41Å; I411-F437 PolarHBondContact N-O 3.31Å; F437-V462 CarbonylContact C-O 3.6Å; F437-V462 WeakPolarHBondContact CA-O 3.43Å; F437-V462 HydrophobicContact CD1-CB 4.21Å; F437-V462 HydrophobicContact CD1-CG1 4.28Å; F437-V462 HydrophobicContact CE1-CG1 4.38Å; F437-I464 HydrophobicContact CB-CD1 3.87Å; F437-I464 HydrophobicContact CB-CG1 4.34Å; F437-I464 HydrophobicContact CD1-CD1 3.94Å; F437-I464 HydrophobicContact CD1-CG1 4.17Å; F437-I464 HydrophobicContact CG-CD1 4.28Å
438W94.7Very high81.5Confident4 Ų442 Ų422%0.01526%0.259CS..EExtended strand (participates in β ladder)trans-133104.4-172.8-169.2-69000110.4I411 G416 L419 L420 L430 V436 L457 V462 L463 I464I411-W438 HydrophobicContact CB-CE3 4.33Å; I411-W438 HydrophobicContact CD1-CE3 3.77Å; I411-W438 HydrophobicContact CD1-CZ3 3.7Å; I411-W438 HydrophobicContact CG2-CE3 4.35Å; I411-W438 HydrophobicContact CG2-CZ3 4.39Å; G416-W438 WeakPolarHBondContact O-CZ2 3.34Å; L419-W438 HydrophobicContact CB-CH2 3.77Å; L419-W438 HydrophobicContact CD1-CH2 4.17Å; L419-W438 HydrophobicContact CD1-CZ3 4.28Å; L420-W438 HydrophobicContact CD1-CZ2 3.78Å; L420-W438 HydrophobicContact CD2-CZ2 4.28Å; L420-W438 HydrophobicContact CG-CH2 4.11Å; L420-W438 HydrophobicContact CG-CZ2 3.58Å; L430-W438 HydrophobicContact CD2-CZ3 3.97Å; V436-W438 HydrophobicContact CG1-CE3 4.31Å; W438-L457 HydrophobicContact CD2-CD1 3.97Å; W438-L457 HydrophobicContact CE3-CD1 4.33Å; W438-L457 HydrophobicContact CE3-CD2 4.21Å; W438-L457 HydrophobicContact CG-CD1 4.18Å; W438-L457 HydrophobicContact CH2-CD2 4.02Å; W438-L457 HydrophobicContact CZ2-CD2 4.37Å; W438-L457 HydrophobicContact CZ3-CD2 3.94Å; W438-V462 PolarHBondContact N-O 2.92Å; W438-L463 HydrophobicContact CB-CD2 4.26Å; W438-L463 HydrophobicContact CG-CD2 4.43Å; W438-L463 CarbonylContact O-C 3.3Å; W438-L463 WeakPolarHBondContact O-CA 3.19Å; W438-I464 PolarHBondContact O-N 2.84Å
439S92.3Very high80.3Confident12 Ų1238.6 Ų38.68%0.08425%0.248CC..EExtended strand (participates in β ladder)trans-73.8127.3172.4-74.30000110.3H410 I411H410-S439 PolarHBondContact CE1-OG 2.97Å; H410-S439 PolarHBondContact NE2-OG 2.8Å; I411-S439 PolarHBondContact O-N 3.22Å
440V83.3Confident79Confident30 Ų3045.1 Ų45.118%0.18228%0.278CS..  trans-79.3141.8177178.50000110M449 L463 I464 L465V440-M449 HydrophobicContact CB-SD 4.41Å; V440-M449 HydrophobicContact CG1-CB 4.22Å; V440-M449 HydrophobicContact CG1-CG 3.91Å; V440-M449 HydrophobicContact CG1-SD 3.56Å; V440-M449 VanDerWaalsContact CG1-SD 3.56Å; V440-M449 HydrophobicContact CG2-SD 3.92Å; V440-L463 HydrophobicContact CG2-CD2 4.37Å; V440-I464 PolarHBondContact N-O 2.94Å; V440-L465 HydrophobicContact CB-CD2 3.97Å; V440-L465 HydrophobicContact CG2-CD2 3.57Å
441A66.6Low77.8Confident25 Ų2546.9 Ų46.921%0.20729%0.288CS..  trans-114.6139.5-178.500000111.5P413 Q417P413-A441 HydrophobicContact CB-CB 3.38Å; P413-A441 WeakPolarHBondContact O-CB 3.4Å; Q417-A441 HydrophobicContact CG-CB 3.64Å
442G58Low76.8Confident38 Ų3846.3 Ų46.339%0.39228%0.279SS..SBendtrans158.1145.5165.600000113.5G444 G445G442-G444 PolarHBondContact O-N 2.73Å; G442-G445 PolarHBondContact O-N 2.86Å
443D54Low75.9Confident176 Ų17641.2 Ų41.294%0.94127%0.266SS*.THydrogen-bonded Turntrans-58.5104.1163-93-20.8000107.9
444G57.3Low75Confident31 Ų3141 Ų4132%0.3227%0.266SS..THydrogen-bonded Turntrans105.62.6-176.300000115.8G442 I446 L447G442-G444 PolarHBondContact O-N 2.73Å; G444-I446 PolarHBondContact O-N 2.92Å; G444-L447 WeakPolarHBondContact O-CB 3.27Å; G444-L447 PolarHBondContact O-N 3.27Å; G444-L447 VanDerWaalsContact O-N 3.13Å
445G65.4Low74.4Confident3 Ų341.6 Ų41.63%0.03126%0.259CS..G310 helixtrans65.3-132.9169.300000113.9G442 L447 G448 M449 E469G442-G445 PolarHBondContact O-N 2.86Å; G445-L447 PolarHBondContact O-N 3.16Å; G445-L447 VanDerWaalsContact O-N 3.13Å; G445-G448 PolarHBondContact O-N 2.77Å; G445-M449 PolarHBondContact O-N 2.91Å; G445-E469 VanDerWaalsContact CA-CD 3.47Å; G445-E469 WeakPolarHBondContact CA-OE1 3.34Å; G445-E469 WeakPolarHBondContact CA-OE2 3.4Å; G445-E469 PolarHBondContact N-OE1 3.4Å
446I64.2Low73.9Confident4 Ų445.2 Ų45.22%0.02128%0.28CS..G310 helixtrans-57.4-25.3175.2-163.3172.7000113.3G444 M449 L465 L470 A475 T478 L479 V482G444-I446 PolarHBondContact O-N 2.92Å; I446-M449 HydrophobicContact CG1-CE 4.37Å; I446-M449 WeakPolarHBondContact O-CB 3.21Å; I446-M449 PolarHBondContact O-N 2.83Å; I446-L465 HydrophobicContact CD1-CD1 4.08Å; I446-L470 HydrophobicContact CD1-CD2 4.41Å; I446-L470 HydrophobicContact CG2-CD2 4.02Å; I446-A475 HydrophobicContact CG2-CB 3.55Å; I446-T478 HydrophobicContact CD1-CG2 4.04Å; I446-T478 HydrophobicContact CG1-CG2 3.84Å; I446-L479 HydrophobicContact CD1-CB 4Å; I446-L479 HydrophobicContact CD1-CD1 4.3Å; I446-V482 HydrophobicContact CD1-CG2 4.32Å
447L58.8Low73.6Confident66 Ų6645.5 Ų45.535%0.34628%0.282SS..G310 helixtrans-77.8-28.2177.8-62.6173.4000112.4G444 G445 M449 K472 E474 A475G444-L447 WeakPolarHBondContact O-CB 3.27Å; G444-L447 PolarHBondContact O-N 3.27Å; G444-L447 VanDerWaalsContact O-N 3.13Å; G445-L447 PolarHBondContact O-N 3.16Å; G445-L447 VanDerWaalsContact O-N 3.13Å; L447-M449 VanDerWaalsContact C-N 3.31Å; L447-K472 HydrophobicContact CD1-CD 3.95Å; L447-E474 HydrophobicContact CD1-CB 4.48Å; L447-E474 HydrophobicContact CD2-CB 3.73Å; L447-A475 HydrophobicContact CD2-CB 4.32Å; L447-A475 HydrophobicContact CG-CB 4.29Å
448G63.8Low73.3Confident48 Ų4847.6 Ų47.650%0.49530%0.295SS..THydrogen-bonded Turntrans-84.7-7.5173.100000113.2G445G445-G448 PolarHBondContact O-N 2.77Å
449M68.6Low73.1Confident25 Ų2553.3 Ų53.312%0.12333%0.333CS..SBendtrans-81.1125.4-177.1-166.5-17685.400111V440 G445 I446 L447 L451 V454V440-M449 HydrophobicContact CB-SD 4.41Å; V440-M449 HydrophobicContact CG1-CB 4.22Å; V440-M449 HydrophobicContact CG1-CG 3.91Å; V440-M449 HydrophobicContact CG1-SD 3.56Å; V440-M449 VanDerWaalsContact CG1-SD 3.56Å; V440-M449 HydrophobicContact CG2-SD 3.92Å; G445-M449 PolarHBondContact O-N 2.91Å; I446-M449 HydrophobicContact CG1-CE 4.37Å; I446-M449 WeakPolarHBondContact O-CB 3.21Å; I446-M449 PolarHBondContact O-N 2.83Å; L447-M449 VanDerWaalsContact C-N 3.31Å; M449-L451 HydrophobicContact CE-CD1 4.01Å; M449-L451 PolarHBondContact O-N 2.9Å; M449-V454 HydrophobicContact CE-CB 3.77Å; M449-V454 HydrophobicContact CE-CG1 4.06Å; M449-V454 HydrophobicContact CE-CG2 3.72Å; M449-V454 HydrophobicContact CG-CG2 3.75Å; M449-V454 HydrophobicContact SD-CB 4.05Å; M449-V454 HydrophobicContact SD-CG1 4.38Å; M449-V454 HydrophobicContact SD-CG2 3.31Å; M449-V454 WeakPolarHBondContact SD-CG2 3.29Å
450E66.8Low73.2Confident138 Ų13854.7 Ų54.765%0.64534%0.339SS*.  trans-67.1105.2163.5-73.8-173.4176.600109S452 A453E450-S452 PolarHBondContact O-N 2.55Å; E450-S452 VanDerWaalsContact O-N 3.09Å; E450-A453 HydrophobicContact CB-CB 4.08Å; E450-A453 WeakPolarHBondContact O-CB 3.46Å; E450-A453 PolarHBondContact O-N 2.99Å
451L68.8Low73.7Confident45 Ų4553.3 Ų53.324%0.23633%0.331CS..Hα-helixtrans-51.9-36.4179.6-142.491.4000112M449 A453 V454 Q455 T478 N481 V482M449-L451 HydrophobicContact CE-CD1 4.01Å; M449-L451 PolarHBondContact O-N 2.9Å; L451-A453 VanDerWaalsContact C-N 3.33Å; L451-A453 PolarHBondContact O-N 3.34Å; L451-V454 PolarHBondContact O-N 3.18Å; L451-Q455 WeakPolarHBondContact O-CG 3.36Å; L451-Q455 PolarHBondContact O-N 3.48Å; L451-T478 HydrophobicContact CD1-CG2 3.34Å; L451-N481 HydrophobicContact CD2-CB 4.06Å; L451-V482 HydrophobicContact CD1-CG2 4.04Å
452S72.8Confident75.1Confident72 Ų7252.4 Ų52.450%0.50332%0.323SS..Hα-helixtrans-59.6-38175.945.90000113.1E450 V454 V456E450-S452 PolarHBondContact O-N 2.55Å; E450-S452 VanDerWaalsContact O-N 3.09Å; S452-V454 VanDerWaalsContact C-N 3.34Å; S452-V456 WeakPolarHBondContact O-CG2 3.5Å
453A76.1Confident76.8Confident32 Ų3250.6 Ų50.626%0.26430%0.304SS..Hα-helixtrans-69.5-34.7-179.300000111.9L420 E450 L451L420-A453 WeakPolarHBondContact CD2-O 3.47Å; E450-A453 HydrophobicContact CB-CB 4.08Å; E450-A453 WeakPolarHBondContact O-CB 3.46Å; E450-A453 PolarHBondContact O-N 2.99Å; L451-A453 VanDerWaalsContact C-N 3.33Å; L451-A453 PolarHBondContact O-N 3.34Å
454V77.3Confident78.7Confident5 Ų542.5 Ų42.53%0.0326%0.261CS..Hα-helixtrans-81.2-30.3179.7170.20000112.7M449 L451 S452 V456 L457 L463 Q484M449-V454 HydrophobicContact CE-CB 3.77Å; M449-V454 HydrophobicContact CE-CG1 4.06Å; M449-V454 HydrophobicContact CE-CG2 3.72Å; M449-V454 HydrophobicContact CG-CG2 3.75Å; M449-V454 HydrophobicContact SD-CB 4.05Å; M449-V454 HydrophobicContact SD-CG1 4.38Å; M449-V454 HydrophobicContact SD-CG2 3.31Å; M449-V454 WeakPolarHBondContact SD-CG2 3.29Å; L451-V454 PolarHBondContact O-N 3.18Å; S452-V454 VanDerWaalsContact C-N 3.34Å; V454-V456 PolarHBondContact O-N 3.27Å; V454-L457 HydrophobicContact CG1-CD1 4.3Å; V454-L457 WeakPolarHBondContact O-CB 3.49Å; V454-L457 PolarHBondContact O-N 2.98Å; V454-L463 HydrophobicContact CG1-CD1 3.5Å; V454-L463 VanDerWaalsContact CG1-CD1 3.5Å; V454-L463 HydrophobicContact CG1-CD2 3.78Å; V454-L463 HydrophobicContact CG1-CG 4.25Å; V454-Q484 HydrophobicContact CG1-CG 4.45Å; V454-Q484 PolarHBondContact O-NE2 2.94Å
455Q81.3Confident80.3Confident98 Ų9841.3 Ų41.346%0.45825%0.247SC..Hα-helixtrans-61.4-22.5173.6-78.4178.7-17.200113.5L451 L457L451-Q455 WeakPolarHBondContact O-CG 3.36Å; L451-Q455 PolarHBondContact O-N 3.48Å; Q455-L457 VanDerWaalsContact C-N 3.26Å; Q455-L457 PolarHBondContact O-N 3.35Å
456V87.6Confident81.4Confident98 Ų9844 Ų4459%0.59426%0.259SS*.THydrogen-bonded Turntrans-74.4-17.2176-176.90000112.1L423 S452 V454L423-V456 HydrophobicContact CD1-CB 4.34Å; L423-V456 HydrophobicContact CD1-CG1 3.7Å; S452-V456 WeakPolarHBondContact O-CG2 3.5Å; V454-V456 PolarHBondContact O-N 3.27Å
457L91Very high82.6Confident6 Ų643.9 Ų43.93%0.03126%0.258CS..SBendtrans-67138.8-178.6-67.6176.8000111.7L420 L423 W438 V454 Q455 C461 L463L420-L457 HydrophobicContact CD2-CD2 3.86Å; L420-L457 HydrophobicContact CD2-CG 4.23Å; L423-L457 HydrophobicContact CD2-CD2 4.13Å; W438-L457 HydrophobicContact CD2-CD1 3.97Å; W438-L457 HydrophobicContact CE3-CD1 4.33Å; W438-L457 HydrophobicContact CE3-CD2 4.21Å; W438-L457 HydrophobicContact CG-CD1 4.18Å; W438-L457 HydrophobicContact CH2-CD2 4.02Å; W438-L457 HydrophobicContact CZ2-CD2 4.37Å; W438-L457 HydrophobicContact CZ3-CD2 3.94Å; V454-L457 HydrophobicContact CG1-CD1 4.3Å; V454-L457 WeakPolarHBondContact O-CB 3.49Å; V454-L457 PolarHBondContact O-N 2.98Å; Q455-L457 VanDerWaalsContact C-N 3.26Å; Q455-L457 PolarHBondContact O-N 3.35Å; L457-C461 HydrophobicContact CB-CB 4.09Å; L457-C461 HydrophobicContact CD1-CB 4.47Å; L457-L463 HydrophobicContact CD1-CD2 4.04Å
458P90.9Very high83.7Confident44 Ų4444.5 Ų44.529%0.28626%0.259SS..  trans-55.3153.6174-29.637.7000113.8L430 N460 C461L430-P458 HydrophobicContact CB-CG 4.42Å; L430-P458 HydrophobicContact CD1-CG 4.15Å; P458-N460 WeakPolarHBondContact CB-OD1 3.27Å; P458-N460 PolarHBondContact O-N 3.38Å; P458-N460 VanDerWaalsContact O-N 3.15Å; P458-C461 VanDerWaalsContact O-CB 3.24Å; P458-C461 WeakPolarHBondContact O-CB 3.3Å; P458-C461 PolarHBondContact O-N 2.8Å; P458-C461 PolarHBondContact O-SG 3.48Å
459P89.9Confident84.4Confident123 Ų12344.7 Ų44.780%0.79925%0.247SC*.THydrogen-bonded Turntrans-68-15.1-17627.8-36.3000114.7C461P459-C461 PolarHBondContact O-N 2.71Å
460N94Very high85.1Confident42 Ų4243.6 Ų43.623%0.22524%0.242CC..THydrogen-bonded Turntrans-77.8-3170.764.6-43.2000112.9L430 Y433 S434 C435 V436 P458L430-N460 PolarHBondContact O-ND2 3.18Å; Y433-N460 PolarHBondContact O-ND2 2.92Å; S434-N460 WeakPolarHBondContact O-CB 3.15Å; C435-N460 WeakPolarHBondContact CA-O 3.31Å; V436-N460 PolarHBondContact N-O 3.01Å; P458-N460 WeakPolarHBondContact CB-OD1 3.27Å; P458-N460 PolarHBondContact O-N 3.38Å; P458-N460 VanDerWaalsContact O-N 3.15Å
461C94.3Very high85.5Confident0 Ų039 Ų390%023%0.231CC..EExtended strand (participates in β ladder)trans-84.5122.9174.6-61.50000110.7V436 L457 P458 P459 P485V436-C461 CarbonylContact O-C 3.5Å; V436-C461 VanDerWaalsContact O-CA 3.24Å; V436-C461 WeakPolarHBondContact O-CA 3.29Å; L457-C461 HydrophobicContact CB-CB 4.09Å; L457-C461 HydrophobicContact CD1-CB 4.47Å; P458-C461 VanDerWaalsContact O-CB 3.24Å; P458-C461 WeakPolarHBondContact O-CB 3.3Å; P458-C461 PolarHBondContact O-N 2.8Å; P458-C461 PolarHBondContact O-SG 3.48Å; P459-C461 PolarHBondContact O-N 2.71Å; C461-P485 WeakPolarHBondContact O-CD 3.38Å; C461-P485 WeakPolarHBondContact O-CG 3.24Å
462V95.4Very high86Confident6 Ų642.3 Ų42.34%0.03624%0.244CC..EExtended strand (participates in β ladder)trans-107.2116.4176.7-178.40000109I308 V436 F437 W438 P485 C487 L522I308-V462 HydrophobicContact CD1-CG1 4.42Å; V436-V462 PolarHBondContact O-N 3.34Å; F437-V462 CarbonylContact C-O 3.6Å; F437-V462 WeakPolarHBondContact CA-O 3.43Å; F437-V462 HydrophobicContact CD1-CB 4.21Å; F437-V462 HydrophobicContact CD1-CG1 4.28Å; F437-V462 HydrophobicContact CE1-CG1 4.38Å; W438-V462 PolarHBondContact N-O 2.92Å; V462-P485 CarbonylContact C-O 3.56Å; V462-P485 WeakPolarHBondContact CA-O 3.24Å; V462-P485 HydrophobicContact CB-CG 4.46Å; V462-P485 HydrophobicContact CG1-CB 4.45Å; V462-P485 HydrophobicContact CG2-CB 4.23Å; V462-P485 HydrophobicContact CG2-CG 3.9Å; V462-C487 HydrophobicContact CG1-CB 4.34Å; V462-C487 VanDerWaalsContact CG1-SG 3.57Å; V462-L522 HydrophobicContact CG1-CD1 4.27Å; V462-L522 HydrophobicContact CG2-CD1 3.96Å
463L93.7Very high86.1Confident1 Ų145.7 Ų45.71%0.00526%0.255CS..EExtended strand (participates in β ladder)trans-74.2131.1-178.9-54.1177.5000110.5W438 V440 V454 L457 L465 V482 Q484 P485 V486 C487W438-L463 HydrophobicContact CB-CD2 4.26Å; W438-L463 HydrophobicContact CG-CD2 4.43Å; W438-L463 CarbonylContact O-C 3.3Å; W438-L463 WeakPolarHBondContact O-CA 3.19Å; V440-L463 HydrophobicContact CG2-CD2 4.37Å; V454-L463 HydrophobicContact CG1-CD1 3.5Å; V454-L463 VanDerWaalsContact CG1-CD1 3.5Å; V454-L463 HydrophobicContact CG1-CD2 3.78Å; V454-L463 HydrophobicContact CG1-CG 4.25Å; L457-L463 HydrophobicContact CD1-CD2 4.04Å; L463-L465 HydrophobicContact CB-CD2 4.4Å; L463-L465 HydrophobicContact CB-CG 4.45Å; L463-V482 HydrophobicContact CD1-CG1 3.72Å; L463-Q484 HydrophobicContact CD1-CB 3.79Å; L463-Q484 HydrophobicContact CD1-CG 4.45Å; L463-Q484 HydrophobicContact CG-CB 3.99Å; L463-P485 PolarHBondContact N-O 3.08Å; L463-V486 HydrophobicContact CB-CG2 4.34Å; L463-V486 HydrophobicContact CD1-CG2 4.49Å; L463-V486 CarbonylContact O-C 3.12Å; L463-V486 WeakPolarHBondContact O-CA 3.42Å; L463-C487 PolarHBondContact O-N 3.41Å
464I94Very high85.9Confident6 Ų650.5 Ų50.53%0.03127%0.272CS..EExtended strand (participates in β ladder)trans-99.5118.9169.3-61.4-174.1000107.9L342 F437 W438 V440 C487 V525L342-I464 HydrophobicContact CD2-CD1 4.02Å; F437-I464 HydrophobicContact CB-CD1 3.87Å; F437-I464 HydrophobicContact CB-CG1 4.34Å; F437-I464 HydrophobicContact CD1-CD1 3.94Å; F437-I464 HydrophobicContact CD1-CG1 4.17Å; F437-I464 HydrophobicContact CG-CD1 4.28Å; W438-I464 PolarHBondContact O-N 2.84Å; V440-I464 PolarHBondContact N-O 2.94Å; I464-C487 WeakPolarHBondContact CA-O 3.41Å; I464-C487 HydrophobicContact CG1-CB 4.37Å; I464-V525 HydrophobicContact CD1-CG2 4.19Å
465L90.9Very high85.8Confident6 Ų650.3 Ų50.33%0.03127%0.271CS..EExtended strand (participates in β ladder)trans-120.8132.4-176.6-57.9-177.9000111V440 I446 L463 L467 L470 L479 V486 C487 S489V440-L465 HydrophobicContact CB-CD2 3.97Å; V440-L465 HydrophobicContact CG2-CD2 3.57Å; I446-L465 HydrophobicContact CD1-CD1 4.08Å; L463-L465 HydrophobicContact CB-CD2 4.4Å; L463-L465 HydrophobicContact CB-CG 4.45Å; L465-L467 PolarHBondContact O-N 2.73Å; L465-L470 HydrophobicContact CB-CD1 4.01Å; L465-L470 HydrophobicContact CD1-CD1 4.43Å; L465-L470 HydrophobicContact CD1-CD2 4.43Å; L465-L479 HydrophobicContact CD1-CD1 3.7Å; L465-V486 HydrophobicContact CB-CG1 4.39Å; L465-V486 HydrophobicContact CD1-CG1 3.6Å; L465-V486 HydrophobicContact CD1-CG2 4.28Å; L465-V486 HydrophobicContact CG-CG1 3.91Å; L465-C487 PolarHBondContact N-O 3.34Å; L465-S489 VanDerWaalsContact C-OG 3.32Å; L465-S489 PolarHBondContact O-N 2.93Å; L465-S489 PolarHBondContact O-OG 2.82Å
466E89.7Confident85.6Confident58 Ų5847.4 Ų47.427%0.27126%0.257SS..EExtended strand (participates in β ladder)trans-68.4125.5179-63.5-159.8167.200111.6E468 E469 L470 S489 R491E466-E468 VanDerWaalsContact C-N 3.29Å; E466-E468 PolarHBondContact O-N 2.86Å; E466-E469 HydrophobicContact CB-CG 4.12Å; E466-E469 PolarHBondContact O-N 3.11Å; E466-L470 PolarHBondContact O-N 3.09Å; E466-S489 WeakPolarHBondContact CA-OG 3.46Å; E466-S489 PolarHBondContact N-OG 2.92Å; E466-R491 IonicContact OE1-CZ 3.46Å; E466-R491 IonicContact OE1-NE 2.69Å; E466-R491 IonicContact OE1-NH2 2.7Å; E466-R491 PolarHBondContact OE1-NH2 2.86Å; E466-R491 IonicContact OE2-NE 3.58Å; E466-R491 IonicContact OE2-NH2 2.84Å
467L89.4Confident85.2Confident2 Ų246.1 Ų46.11%0.0125%0.253CS..THydrogen-bonded Turntrans-59.7-38.9-175.8-175.970.3000112.4L465 E469 L470 G471 L488 S489 L490 N508 L511 L512 L515L465-L467 PolarHBondContact O-N 2.73Å; L467-E469 VanDerWaalsContact C-N 3.28Å; L467-E469 PolarHBondContact O-N 2.98Å; L467-L470 PolarHBondContact O-N 2.85Å; L467-G471 PolarHBondContact O-N 2.92Å; L467-L488 HydrophobicContact CD1-CB 4.43Å; L467-L488 HydrophobicContact CD1-CD1 4.35Å; L467-S489 WeakPolarHBondContact CB-O 3.44Å; L467-S489 PolarHBondContact N-O 2.81Å; L467-L490 HydrophobicContact CB-CB 4.41Å; L467-L490 HydrophobicContact CD2-CB 4.21Å; L467-N508 HydrophobicContact CD2-CB 3.85Å; L467-L511 HydrophobicContact CD1-CB 4.32Å; L467-L511 HydrophobicContact CD1-CD2 3.96Å; L467-L511 HydrophobicContact CD1-CG 3.79Å; L467-L511 HydrophobicContact CG-CD2 3.89Å; L467-L511 HydrophobicContact CG-CG 4.2Å; L467-L511 WeakPolarHBondContact O-CD2 3.49Å; L467-L512 HydrophobicContact CD1-CD2 3.84Å; L467-L512 HydrophobicContact CD1-CG 4.17Å; L467-L512 HydrophobicContact CD2-CD1 4.39Å; L467-L512 HydrophobicContact CD2-CD2 4Å; L467-L512 HydrophobicContact CD2-CG 3.74Å; L467-L515 HydrophobicContact CD1-CD1 3.81Å
468E82.2Confident84.5Confident80 Ų8047.4 Ų47.437%0.37426%0.261SS..THydrogen-bonded Turntrans-61.5-36.9-178.3-66.3-170.8-172.900112E466 L470 G471E466-E468 VanDerWaalsContact C-N 3.29Å; E466-E468 PolarHBondContact O-N 2.86Å; E468-L470 VanDerWaalsContact C-N 3.34Å; E468-G471 PolarHBondContact O-N 3.3Å
469E78.3Confident84.1Confident52 Ų5245.4 Ų45.424%0.24325%0.248CC..G310 helixtrans-70.3-33.8179.2-58.1-174.4135.600112G445 E466 L467 G471 K472 A475G445-E469 VanDerWaalsContact CA-CD 3.47Å; G445-E469 WeakPolarHBondContact CA-OE1 3.34Å; G445-E469 WeakPolarHBondContact CA-OE2 3.4Å; G445-E469 PolarHBondContact N-OE1 3.4Å; E466-E469 HydrophobicContact CB-CG 4.12Å; E466-E469 PolarHBondContact O-N 3.11Å; L467-E469 VanDerWaalsContact C-N 3.28Å; L467-E469 PolarHBondContact O-N 2.98Å; E469-G471 PolarHBondContact O-N 2.9Å; E469-K472 PolarHBondContact O-N 3.39Å; E469-A475 WeakPolarHBondContact O-CB 3.39Å
470L81.7Confident83.5Confident2 Ų242.8 Ų42.81%0.0124%0.236CC..G310 helixtrans-74.1-5.1177-61.8174.9000113.5I446 L465 E466 L467 E468 K472 A475 Q476 L479 L488 L515I446-L470 HydrophobicContact CD1-CD2 4.41Å; I446-L470 HydrophobicContact CG2-CD2 4.02Å; L465-L470 HydrophobicContact CB-CD1 4.01Å; L465-L470 HydrophobicContact CD1-CD1 4.43Å; L465-L470 HydrophobicContact CD1-CD2 4.43Å; E466-L470 PolarHBondContact O-N 3.09Å; L467-L470 PolarHBondContact O-N 2.85Å; E468-L470 VanDerWaalsContact C-N 3.34Å; L470-K472 PolarHBondContact O-N 3.28Å; L470-A475 HydrophobicContact CD2-CB 4.22Å; L470-Q476 VanDerWaalsContact O-CG 3.28Å; L470-Q476 WeakPolarHBondContact O-CG 3.39Å; L470-Q476 PolarHBondContact O-NE2 3.18Å; L470-L479 HydrophobicContact CD1-CD2 4.17Å; L470-L479 HydrophobicContact CD2-CD2 4.09Å; L470-L488 HydrophobicContact CD1-CD2 3.48Å; L470-L488 VanDerWaalsContact CD1-CD2 3.48Å; L470-L515 HydrophobicContact CB-CD1 3.79Å; L470-L515 HydrophobicContact CD1-CD1 4.01Å
471G75.9Confident82.9Confident41 Ų4145.6 Ų45.642%0.42325%0.252SS..G310 helixtrans-63.4-26.2169.700000112.8L467 E468 E469L467-G471 PolarHBondContact O-N 2.92Å; E468-G471 PolarHBondContact O-N 3.3Å; E469-G471 PolarHBondContact O-N 2.9Å
472K79.2Confident82.4Confident115 Ų11545.9 Ų45.950%0.525%0.253SS..SBendtrans-73.3136.6179.4-61175.3-175.9172.60110.9L447 E469 L470 E474 A475 Q476L447-K472 HydrophobicContact CD1-CD 3.95Å; E469-K472 PolarHBondContact O-N 3.39Å; L470-K472 PolarHBondContact O-N 3.28Å; K472-E474 VanDerWaalsContact C-N 3.31Å; K472-E474 PolarHBondContact O-N 2.91Å; K472-A475 HydrophobicContact CB-CB 4.17Å; K472-A475 WeakPolarHBondContact O-CB 3.29Å; K472-A475 PolarHBondContact O-N 3.37Å; K472-A475 VanDerWaalsContact O-N 3.16Å; K472-Q476 PolarHBondContact O-N 2.94Å
473I74.9Confident81.9Confident143 Ų14352.3 Ų52.373%0.73329%0.287SS*.Hα-helixtrans-59-43.1-177.6-63172.9000111.2A475 Q476 S477I473-A475 VanDerWaalsContact C-N 3.32Å; I473-A475 PolarHBondContact O-N 2.83Å; I473-Q476 WeakPolarHBondContact O-CB 3.4Å; I473-Q476 PolarHBondContact O-N 2.86Å; I473-S477 PolarHBondContact O-N 3.14Å
474E73Confident81.7Confident132 Ų13253.1 Ų53.162%0.61729%0.291SS*.Hα-helixtrans-58.7-43.8178.1-64.6173179.600111.4L447 K472 Q476 S477 T478L447-E474 HydrophobicContact CD1-CB 4.48Å; L447-E474 HydrophobicContact CD2-CB 3.73Å; K472-E474 VanDerWaalsContact C-N 3.31Å; K472-E474 PolarHBondContact O-N 2.91Å; E474-Q476 VanDerWaalsContact C-N 3.27Å; E474-Q476 PolarHBondContact O-N 3.47Å; E474-S477 PolarHBondContact O-N 3.46Å; E474-S477 VanDerWaalsContact O-N 3.09Å; E474-S477 PolarHBondContact O-OG 2.99Å; E474-T478 PolarHBondContact O-N 2.96Å; E474-T478 PolarHBondContact O-OG1 3.29Å; E474-T478 VanDerWaalsContact O-OG1 3.12Å
475A74.8Confident81.7Confident1 Ų154.1 Ų54.11%0.00830%0.298CS..Hα-helixtrans-61.9-35.3179.500000112.2I446 L447 E469 L470 K472 I473 T478 L479I446-A475 HydrophobicContact CG2-CB 3.55Å; L447-A475 HydrophobicContact CD2-CB 4.32Å; L447-A475 HydrophobicContact CG-CB 4.29Å; E469-A475 WeakPolarHBondContact O-CB 3.39Å; L470-A475 HydrophobicContact CD2-CB 4.22Å; K472-A475 HydrophobicContact CB-CB 4.17Å; K472-A475 WeakPolarHBondContact O-CB 3.29Å; K472-A475 PolarHBondContact O-N 3.37Å; K472-A475 VanDerWaalsContact O-N 3.16Å; I473-A475 VanDerWaalsContact C-N 3.32Å; I473-A475 PolarHBondContact O-N 2.83Å; A475-T478 PolarHBondContact O-N 3.06Å; A475-L479 WeakPolarHBondContact O-CB 3.21Å; A475-L479 PolarHBondContact O-N 2.9Å
476Q76.8Confident81.7Confident38 Ų3854 Ų5418%0.17830%0.297CS..Hα-helixtrans-68.5-36.9176-65.8172.511.400112.2L470 K472 I473 E474 A480 L515L470-Q476 VanDerWaalsContact O-CG 3.28Å; L470-Q476 WeakPolarHBondContact O-CG 3.39Å; L470-Q476 PolarHBondContact O-NE2 3.18Å; K472-Q476 PolarHBondContact O-N 2.94Å; I473-Q476 WeakPolarHBondContact O-CB 3.4Å; I473-Q476 PolarHBondContact O-N 2.86Å; E474-Q476 VanDerWaalsContact C-N 3.27Å; E474-Q476 PolarHBondContact O-N 3.47Å; Q476-A480 PolarHBondContact O-N 3.3Å; Q476-L515 HydrophobicContact CG-CD2 4.17Å
477S79.6Confident82Confident71 Ų7151.2 Ų51.250%0.49728%0.284SS..Hα-helixtrans-67.7-39.1174.367.30000112.2I473 E474 A480 N481I473-S477 PolarHBondContact O-N 3.14Å; E474-S477 PolarHBondContact O-N 3.46Å; E474-S477 VanDerWaalsContact O-N 3.09Å; E474-S477 PolarHBondContact O-OG 2.99Å; S477-A480 PolarHBondContact O-N 3.48Å; S477-N481 PolarHBondContact O-ND2 3.34Å
478T76.5Confident82.2Confident32 Ų3251.1 Ų51.120%0.19628%0.284CS..Hα-helixtrans-64.8-44.1175.5-52.70000111.2I446 L451 E474 A475 A480 N481I446-T478 HydrophobicContact CD1-CG2 4.04Å; I446-T478 HydrophobicContact CG1-CG2 3.84Å; L451-T478 HydrophobicContact CD1-CG2 3.34Å; E474-T478 PolarHBondContact O-N 2.96Å; E474-T478 PolarHBondContact O-OG1 3.29Å; E474-T478 VanDerWaalsContact O-OG1 3.12Å; A475-T478 PolarHBondContact O-N 3.06Å; T478-A480 PolarHBondContact O-N 3.39Å; T478-N481 WeakPolarHBondContact O-CB 3.46Å; T478-N481 PolarHBondContact O-N 3.1Å
479L81.5Confident82.8Confident2 Ų247.6 Ų47.61%0.0127%0.268CS..Hα-helixtrans-60-32.4178-178.360.2000113.1I446 L465 L470 A475 N481 V482 V486 L515 L518 N520I446-L479 HydrophobicContact CD1-CB 4Å; I446-L479 HydrophobicContact CD1-CD1 4.3Å; L465-L479 HydrophobicContact CD1-CD1 3.7Å; L470-L479 HydrophobicContact CD1-CD2 4.17Å; L470-L479 HydrophobicContact CD2-CD2 4.09Å; A475-L479 WeakPolarHBondContact O-CB 3.21Å; A475-L479 PolarHBondContact O-N 2.9Å; L479-N481 PolarHBondContact O-N 2.93Å; L479-V482 PolarHBondContact O-N 2.64Å; L479-V486 HydrophobicContact CD1-CG1 4.25Å; L479-V486 HydrophobicContact CD1-CG2 3.91Å; L479-L515 HydrophobicContact CD2-CD2 4.4Å; L479-L518 HydrophobicContact CD2-CD1 3.34Å; L479-L518 HydrophobicContact CG-CD1 3.87Å; L479-N520 PolarHBondContact O-ND2 3.4Å
480A78.7Confident83.5Confident68 Ų6845.6 Ų45.656%0.56226%0.259SS*.THydrogen-bonded Turntrans-66.8-20.317600000113.3Q476 S477 T478Q476-A480 PolarHBondContact O-N 3.3Å; S477-A480 PolarHBondContact O-N 3.48Å; T478-A480 PolarHBondContact O-N 3.39Å
481N81.1Confident84Confident102 Ų10248.6 Ų48.655%0.54527%0.27SS..THydrogen-bonded Turntrans-96.12.1177.8-61-34.9000113.1L451 S477 T478 L479L451-N481 HydrophobicContact CD2-CB 4.06Å; S477-N481 PolarHBondContact O-ND2 3.34Å; T478-N481 WeakPolarHBondContact O-CB 3.46Å; T478-N481 PolarHBondContact O-N 3.1Å; L479-N481 PolarHBondContact O-N 2.93Å
482V83.9Confident84.8Confident6 Ų647.3 Ų47.34%0.03626%0.255CS..  trans-90.6113.2179176.90000109.2I446 L451 L463 L479 Q484 V486 N520I446-V482 HydrophobicContact CD1-CG2 4.32Å; L451-V482 HydrophobicContact CD1-CG2 4.04Å; L463-V482 HydrophobicContact CD1-CG1 3.72Å; L479-V482 PolarHBondContact O-N 2.64Å; V482-Q484 HydrophobicContact CG1-CB 3.97Å; V482-V486 HydrophobicContact CG1-CG2 4.28Å; V482-N520 PolarHBondContact O-ND2 3.41Å
483D84.9Confident85.3Confident140 Ų14042.4 Ų42.475%0.74924%0.235SC*.  trans-78.4-22.2177.6-69.8-36.5000112.8
484Q88.9Confident85.9Confident19 Ų1940.2 Ų40.29%0.08922%0.218CC..SBendtrans-64.4147178-77.967.82400111.5V454 L463 V482V454-Q484 HydrophobicContact CG1-CG 4.45Å; V454-Q484 PolarHBondContact O-NE2 2.94Å; L463-Q484 HydrophobicContact CD1-CB 3.79Å; L463-Q484 HydrophobicContact CD1-CG 4.45Å; L463-Q484 HydrophobicContact CG-CB 3.99Å; V482-Q484 HydrophobicContact CG1-CB 3.97Å
485P93Very high86.3Confident27 Ų2736.3 Ų36.318%0.17520%0.204CC..  trans-64.2142.1170.823.6-28.8000111.5C461 V462 L463 N520 L522C461-P485 WeakPolarHBondContact O-CD 3.38Å; C461-P485 WeakPolarHBondContact O-CG 3.24Å; V462-P485 CarbonylContact C-O 3.56Å; V462-P485 WeakPolarHBondContact CA-O 3.24Å; V462-P485 HydrophobicContact CB-CG 4.46Å; V462-P485 HydrophobicContact CG1-CB 4.45Å; V462-P485 HydrophobicContact CG2-CB 4.23Å; V462-P485 HydrophobicContact CG2-CG 3.9Å; L463-P485 PolarHBondContact N-O 3.08Å; P485-N520 WeakPolarHBondContact CA-O 3.41Å; P485-L522 HydrophobicContact CB-CD1 3.32Å; P485-L522 HydrophobicContact CB-CD2 4.43Å; P485-L522 HydrophobicContact CB-CG 3.6Å; P485-L522 HydrophobicContact CG-CD1 4.22Å
486V92.7Very high86.9Confident2 Ų236.7 Ų36.71%0.01221%0.208CC..EExtended strand (participates in β ladder)trans-125.2139.4-173.9176.70000111.1L463 L465 L479 V482 L488 N520 C521 L522L463-V486 HydrophobicContact CB-CG2 4.34Å; L463-V486 HydrophobicContact CD1-CG2 4.49Å; L463-V486 CarbonylContact O-C 3.12Å; L463-V486 WeakPolarHBondContact O-CA 3.42Å; L465-V486 HydrophobicContact CB-CG1 4.39Å; L465-V486 HydrophobicContact CD1-CG1 3.6Å; L465-V486 HydrophobicContact CD1-CG2 4.28Å; L465-V486 HydrophobicContact CG-CG1 3.91Å; L479-V486 HydrophobicContact CD1-CG1 4.25Å; L479-V486 HydrophobicContact CD1-CG2 3.91Å; V482-V486 HydrophobicContact CG1-CG2 4.28Å; V486-L488 HydrophobicContact CG1-CD2 4.35Å; V486-N520 PolarHBondContact N-O 3.31Å; V486-C521 CarbonylContact O-C 3.55Å; V486-C521 WeakPolarHBondContact O-CA 3.31Å; V486-L522 PolarHBondContact O-N 3.31Å
487C95.2Very high87.7Confident0 Ų036.3 Ų36.30%021%0.205CC..EExtended strand (participates in β ladder)trans-113.3137.2162-71.10000110.2V462 L463 I464 L465 G523 V525V462-C487 HydrophobicContact CG1-CB 4.34Å; V462-C487 VanDerWaalsContact CG1-SG 3.57Å; L463-C487 PolarHBondContact O-N 3.41Å; I464-C487 WeakPolarHBondContact CA-O 3.41Å; I464-C487 HydrophobicContact CG1-CB 4.37Å; L465-C487 PolarHBondContact N-O 3.34Å; C487-G523 CarbonylContact C-O 3.56Å; C487-G523 VanDerWaalsContact CA-O 3.27Å; C487-G523 WeakPolarHBondContact CA-O 3.35Å; C487-V525 HydrophobicContact CB-CG2 3.96Å
488L94.1Very high88.3Confident1 Ų133 Ų331%0.00518%0.182CC..EExtended strand (participates in β ladder)trans-87118.7176.8-54.8174.7000108.6L467 L470 V486 L512 L515 G523 T524 V525L467-L488 HydrophobicContact CD1-CB 4.43Å; L467-L488 HydrophobicContact CD1-CD1 4.35Å; L470-L488 HydrophobicContact CD1-CD2 3.48Å; L470-L488 VanDerWaalsContact CD1-CD2 3.48Å; V486-L488 HydrophobicContact CG1-CD2 4.35Å; L488-L512 HydrophobicContact CB-CD2 3.89Å; L488-L512 HydrophobicContact CD1-CD2 3.74Å; L488-L512 HydrophobicContact CG-CD2 4.48Å; L488-L515 HydrophobicContact CD1-CB 3.67Å; L488-L515 HydrophobicContact CD1-CD1 4.36Å; L488-L515 HydrophobicContact CD2-CB 4.46Å; L488-L515 HydrophobicContact CD2-CD1 4.22Å; L488-G523 PolarHBondContact N-O 3.23Å; L488-T524 CarbonylContact O-C 3.11Å; L488-T524 VanDerWaalsContact O-CA 3.27Å; L488-T524 WeakPolarHBondContact O-CA 3.29Å; L488-V525 PolarHBondContact O-N 3.21Å
489S94.1Very high88.9Confident5 Ų531.7 Ų31.74%0.03517%0.174CC..EExtended strand (participates in β ladder)trans-94139.9172.657.30000111.4L465 E466 L467 V525L465-S489 VanDerWaalsContact C-OG 3.32Å; L465-S489 PolarHBondContact O-N 2.93Å; L465-S489 PolarHBondContact O-OG 2.82Å; E466-S489 WeakPolarHBondContact CA-OG 3.46Å; E466-S489 PolarHBondContact N-OG 2.92Å; L467-S489 WeakPolarHBondContact CB-O 3.44Å; L467-S489 PolarHBondContact N-O 2.81Å; S489-V525 CarbonylContact C-O 3.23Å; S489-V525 VanDerWaalsContact CA-O 3.27Å; S489-V525 WeakPolarHBondContact CA-O 3.43Å
490L93.2Very high89.3Confident10 Ų1032.3 Ų32.35%0.05218%0.177CC..EExtended strand (participates in β ladder)trans-133148.6170.464.8157.2000109.4L467 L512 T524 V525 I526 C527 A548L467-L490 HydrophobicContact CB-CB 4.41Å; L467-L490 HydrophobicContact CD2-CB 4.21Å; L490-L512 HydrophobicContact CD1-CD1 4.3Å; L490-L512 HydrophobicContact CD2-CD1 4.3Å; L490-T524 HydrophobicContact CD2-CG2 3.21Å; L490-V525 PolarHBondContact N-O 3.27Å; L490-I526 HydrophobicContact CD1-CD1 4.08Å; L490-I526 HydrophobicContact CG-CD1 3.8Å; L490-C527 PolarHBondContact O-N 2.95Å; L490-A548 HydrophobicContact CD1-CB 4.05Å; L490-A548 HydrophobicContact CD2-CB 4.08Å; L490-A548 HydrophobicContact CG-CB 4.47Å
491R92.2Very high90Very high66 Ų6629.4 Ų29.425%0.24915%0.152CC..EExtended strand (participates in β ladder)trans-86.1150.3-179.9-58.8-179.5171.8-103-5110.2E466 A493 C527 Y529E466-R491 IonicContact OE1-CZ 3.46Å; E466-R491 IonicContact OE1-NE 2.69Å; E466-R491 IonicContact OE1-NH2 2.7Å; E466-R491 PolarHBondContact OE1-NH2 2.86Å; E466-R491 IonicContact OE2-NE 3.58Å; E466-R491 IonicContact OE2-NH2 2.84Å; R491-A493 VanDerWaalsContact C-N 3.26Å; R491-A493 VanDerWaalsContact CB-O 3.23Å; R491-A493 WeakPolarHBondContact CB-O 3.49Å; R491-A493 PolarHBondContact O-N 3.34Å; R491-C527 CarbonylContact C-O 3.57Å; R491-C527 WeakPolarHBondContact CA-O 3.42Å; R491-Y529 HydrophobicContact CG-CD2 3.86Å; R491-Y529 HydrophobicContact CG-CE2 3.92Å
492S92.2Very high90.6Very high14 Ų1426.2 Ų26.210%0.09814%0.14CC..SBendtrans-63.3-34.9171.257.60000111.9C527 P544S492-C527 PolarHBondContact N-O 3.15Å; S492-C527 PolarHBondContact OG-O 3.49Å; S492-P544 WeakPolarHBondContact O-CG 3.33Å
493A89.9Confident91Very high11 Ų1132.9 Ų32.99%0.09117%0.171CC..SBendtrans-142.9152.2170.100000109.8R491R491-A493 VanDerWaalsContact C-N 3.26Å; R491-A493 VanDerWaalsContact CB-O 3.23Å; R491-A493 WeakPolarHBondContact CB-O 3.49Å; R491-A493 PolarHBondContact O-N 3.34Å
494R86.9Confident91.3Very high97 Ų9727.1 Ų27.137%0.36614%0.14SC..  trans-49.6143.4168.4178.7173.9-98.2-167.3-10.5111.1G496 Y497 E500R494-G496 PolarHBondContact O-N 3.24Å; R494-Y497 HydrophobicContact CB-CD2 4.06Å; R494-Y497 HydrophobicContact CB-CG 4.41Å; R494-Y497 HydrophobicContact CG-CD2 3.91Å; R494-Y497 HydrophobicContact CG-CE2 4.28Å; R494-Y497 PolarHBondContact O-N 3.12Å; R494-Y497 VanDerWaalsContact O-N 3.11Å; R494-E500 PolarHBondContact N-OE2 3.03Å
495P83.2Confident91.6Very high50 Ų5026.4 Ų26.433%0.32514%0.137SC..THydrogen-bonded Turntrans-50.1130.2173.1-28.736.7000111.8Y497 V607P495-Y497 WeakPolarHBondContact O-CD2 3.29Å; P495-V607 VanDerWaalsContact O-O 3.1Å
496G87.3Confident91.7Very high10 Ų1026.5 Ų26.510%0.10314%0.14CC..THydrogen-bonded Turntrans78.412178.500000116.2R494 S609 V612R494-G496 PolarHBondContact O-N 3.24Å; G496-S609 WeakPolarHBondContact O-CB 3.38Å; G496-S609 PolarHBondContact O-N 2.85Å; G496-S609 PolarHBondContact O-OG 3.47Å; G496-V612 VanDerWaalsContact O-CG2 3.3Å; G496-V612 WeakPolarHBondContact O-CG2 3.35Å
497Y91.7Very high91.6Very high30 Ų3030 Ų3012%0.11817%0.165CC..  trans-118.1155.4173.3-73.6-107.3000110.4R494 P495 E594R494-Y497 HydrophobicContact CB-CD2 4.06Å; R494-Y497 HydrophobicContact CB-CG 4.41Å; R494-Y497 HydrophobicContact CG-CD2 3.91Å; R494-Y497 HydrophobicContact CG-CE2 4.28Å; R494-Y497 PolarHBondContact O-N 3.12Å; R494-Y497 VanDerWaalsContact O-N 3.11Å; P495-Y497 WeakPolarHBondContact O-CD2 3.29Å; Y497-E594 WeakPolarHBondContact CA-OE1 3.24Å; Y497-E594 HydrophobicContact CD1-CG 3.78Å; Y497-E594 HydrophobicContact CE1-CG 4.24Å
498F92.2Very high91.5Very high2 Ų230.8 Ų30.81%0.00917%0.169CC..SBendtrans-79.4-37.2177.7-59.9-39.3000113.2C533 I535 V536 L540 E594 F611 V612 L615 V681 M685F498-C533 HydrophobicContact CE1-CB 4.22Å; F498-C533 VanDerWaalsContact CE1-SG 3.56Å; F498-I535 HydrophobicContact CE1-CG2 4.18Å; F498-V536 HydrophobicContact CB-CG2 4.27Å; F498-V536 HydrophobicContact CD1-CG2 3.46Å; F498-V536 VanDerWaalsContact CD1-CG2 3.46Å; F498-V536 HydrophobicContact CE1-CG2 4.25Å; F498-V536 HydrophobicContact CG-CG2 4.27Å; F498-L540 HydrophobicContact CB-CD1 4.35Å; F498-L540 WeakPolarHBondContact O-CD1 3.1Å; F498-E594 PolarHBondContact N-OE1 3.32Å; F498-E594 VanDerWaalsContact N-OE1 3.08Å; F498-E594 PolarHBondContact N-OE2 3.16Å; F498-E594 VanDerWaalsContact N-OE2 3.07Å; F498-F611 HydrophobicContact CE2-CB 3.7Å; F498-F611 HydrophobicContact CZ-CB 4.19Å; F498-V612 HydrophobicContact CD1-CG2 3.87Å; F498-V612 HydrophobicContact CE1-CG2 3.33Å; F498-V612 HydrophobicContact CZ-CG2 3.68Å; F498-L615 HydrophobicContact CE1-CD1 4.31Å; F498-L615 HydrophobicContact CE2-CD1 4.46Å; F498-L615 HydrophobicContact CZ-CD1 3.57Å; F498-V681 HydrophobicContact CB-CG1 4.34Å; F498-V681 HydrophobicContact CD2-CG1 3.99Å; F498-V681 HydrophobicContact CG-CG1 4.25Å; F498-M685 HydrophobicContact CD2-CG 3.98Å; F498-M685 HydrophobicContact CD2-SD 3.99Å; F498-M685 HydrophobicContact CE2-CG 3.75Å; F498-M685 HydrophobicContact CE2-SD 4.37Å
499C89.9Confident91.5Very high4 Ų430.9 Ų30.93%0.02717%0.169CC..SBendtrans-150.3156.9-173.349.10000111.4L540 I587 M590 A591 E594C499-L540 HydrophobicContact CB-CD1 4.26Å; C499-I587 HydrophobicContact CB-CG2 4.43Å; C499-M590 HydrophobicContact CB-CE 4.26Å; C499-M590 VanDerWaalsContact SG-CE 3.52Å; C499-A591 HydrophobicContact CB-CB 4.15Å; C499-A591 WeakPolarHBondContact SG-CA 3.46Å; C499-A591 WeakPolarHBondContact SG-CB 3.32Å; C499-E594 PolarHBondContact N-OE2 3.05Å
500E90.3Very high91.4Very high14 Ų1433.1 Ų33.17%0.06519%0.188CC..  trans-96146.4-179.1-164.351.2-89.100112.6R494 I504 L505 A591R494-E500 PolarHBondContact N-OE2 3.03Å; E500-I504 HydrophobicContact CG-CB 3.94Å; E500-I504 HydrophobicContact CG-CG2 3.86Å; E500-I504 VanDerWaalsContact OE1-CB 3.26Å; E500-I504 WeakPolarHBondContact OE1-CB 3.47Å; E500-I504 WeakPolarHBondContact OE1-CD1 3.38Å; E500-L505 HydrophobicContact CB-CD2 4.23Å; E500-L505 HydrophobicContact CB-CG 4.3Å; E500-L505 HydrophobicContact CG-CD2 3.95Å; E500-L505 HydrophobicContact CG-CG 3.95Å; E500-A591 VanDerWaalsContact O-CB 3.27Å; E500-A591 WeakPolarHBondContact O-CB 3.43Å
501T93.5Very high91.3Very high7 Ų734 Ų344%0.04319%0.193CC..  trans-82151176.7570000112.4E503 I504 L505 A591 R595T501-E503 PolarHBondContact O-N 3.44Å; T501-I504 PolarHBondContact O-N 3.39Å; T501-I504 WeakPolarHBondContact OG1-CG1 3.46Å; T501-I504 PolarHBondContact OG1-N 2.9Å; T501-L505 WeakPolarHBondContact O-CG 3.46Å; T501-L505 PolarHBondContact O-N 3Å; T501-A591 HydrophobicContact CG2-CB 3.86Å; T501-A591 WeakPolarHBondContact CG2-O 3.42Å; T501-R595 HydrophobicContact CG2-CB 3.89Å; T501-R595 HydrophobicContact CG2-CG 4.38Å
502A93.8Very high91.3Very high36 Ų3631.1 Ų31.130%0.29818%0.182SC..Hα-helixtrans-56.5-36.617500000112.4L505 A506 F563 L588A502-L505 PolarHBondContact O-N 3.17Å; A502-A506 WeakPolarHBondContact O-CB 3.34Å; A502-A506 PolarHBondContact O-N 3.46Å; A502-F563 HydrophobicContact CB-CD1 4.41Å; A502-L588 HydrophobicContact CB-CD2 4.05Å
503E92.1Very high91.3Very high146 Ų14633 Ų3368%0.68219%0.188SC*.Hα-helixtrans-62.2-44.6178.5-63.9176.1178.200112.5T501 A506 S507T501-E503 PolarHBondContact O-N 3.44Å; E503-A506 PolarHBondContact O-N 3.1Å; E503-S507 PolarHBondContact O-N 2.82Å
504I91.7Very high91.3Very high19 Ų1938 Ų3810%0.09721%0.208CC..Hα-helixtrans-71.8-41.9177.5-68.7175000110.7E500 T501 A506 S507 N508 R595E500-I504 HydrophobicContact CG-CB 3.94Å; E500-I504 HydrophobicContact CG-CG2 3.86Å; E500-I504 VanDerWaalsContact OE1-CB 3.26Å; E500-I504 WeakPolarHBondContact OE1-CB 3.47Å; E500-I504 WeakPolarHBondContact OE1-CD1 3.38Å; T501-I504 PolarHBondContact O-N 3.39Å; T501-I504 WeakPolarHBondContact OG1-CG1 3.46Å; T501-I504 PolarHBondContact OG1-N 2.9Å; I504-A506 PolarHBondContact O-N 3.4Å; I504-S507 WeakPolarHBondContact O-CB 3.48Å; I504-S507 PolarHBondContact O-N 2.89Å; I504-S507 VanDerWaalsContact O-N 3.13Å; I504-N508 WeakPolarHBondContact O-CB 3.29Å; I504-N508 PolarHBondContact O-N 2.88Å; I504-R595 VanDerWaalsContact CD1-CZ 3.48Å
505L94.7Very high91.4Very high4 Ų433.6 Ų33.62%0.02119%0.192CC..Hα-helixtrans-54.9-42.5173.7-70177.4000110.7E500 T501 A502 N508 C509 P544 F563 L566E500-L505 HydrophobicContact CB-CD2 4.23Å; E500-L505 HydrophobicContact CB-CG 4.3Å; E500-L505 HydrophobicContact CG-CD2 3.95Å; E500-L505 HydrophobicContact CG-CG 3.95Å; T501-L505 WeakPolarHBondContact O-CG 3.46Å; T501-L505 PolarHBondContact O-N 3Å; A502-L505 PolarHBondContact O-N 3.17Å; L505-N508 PolarHBondContact O-N 3.25Å; L505-C509 WeakPolarHBondContact O-CB 3.48Å; L505-C509 PolarHBondContact O-N 3.34Å; L505-C509 PolarHBondContact O-SG 3.47Å; L505-P544 HydrophobicContact CD2-CB 4.12Å; L505-P544 HydrophobicContact CD2-CG 4.2Å; L505-F563 HydrophobicContact CB-CE1 3.65Å; L505-F563 HydrophobicContact CB-CZ 3.86Å; L505-L566 HydrophobicContact CD1-CD2 4.46Å
506A94.1Very high91.6Very high29 Ų2932.4 Ų32.424%0.2419%0.185CC..Hα-helixtrans-65.1-43.7176.300000112.8A502 E503 I504 N508 C509 A510 F563A502-A506 WeakPolarHBondContact O-CB 3.34Å; A502-A506 PolarHBondContact O-N 3.46Å; E503-A506 PolarHBondContact O-N 3.1Å; I504-A506 PolarHBondContact O-N 3.4Å; A506-N508 PolarHBondContact O-N 2.84Å; A506-C509 WeakPolarHBondContact O-CB 3.38Å; A506-C509 PolarHBondContact O-N 3.36Å; A506-A510 PolarHBondContact O-N 3.36Å; A506-F563 HydrophobicContact CB-CD2 3.77Å; A506-F563 HydrophobicContact CB-CE1 4.41Å; A506-F563 HydrophobicContact CB-CE2 3.44Å; A506-F563 VanDerWaalsContact CB-CE2 3.44Å; A506-F563 HydrophobicContact CB-CG 4.45Å; A506-F563 HydrophobicContact CB-CZ 3.8Å; A506-F563 VanDerWaalsContact N-CZ 3.28Å
507S92.4Very high91.6Very high76 Ų7639.4 Ų39.453%0.53121%0.212SC..Hα-helixtrans-59.1-45.4174.1-178.60000112E503 I504 C509 A510 L511E503-S507 PolarHBondContact O-N 2.82Å; I504-S507 WeakPolarHBondContact O-CB 3.48Å; I504-S507 PolarHBondContact O-N 2.89Å; I504-S507 VanDerWaalsContact O-N 3.13Å; S507-C509 VanDerWaalsContact C-N 3.34Å; S507-C509 PolarHBondContact O-N 3.34Å; S507-A510 PolarHBondContact O-N 3.01Å; S507-L511 PolarHBondContact O-N 3.45Å
508N92.8Very high91.2Very high16 Ų1640.6 Ų40.69%0.08622%0.22CC..Hα-helixtrans-63.4-40.5176.9-73-10.6000111.1L467 I504 L505 A506 A510 L511 L512L467-N508 HydrophobicContact CD2-CB 3.85Å; I504-N508 WeakPolarHBondContact O-CB 3.29Å; I504-N508 PolarHBondContact O-N 2.88Å; L505-N508 PolarHBondContact O-N 3.25Å; A506-N508 PolarHBondContact O-N 2.84Å; N508-A510 PolarHBondContact O-N 3.13Å; N508-L511 PolarHBondContact O-N 3.41Å; N508-L512 WeakPolarHBondContact O-CB 3.42Å; N508-L512 WeakPolarHBondContact O-CG 3.48Å; N508-L512 PolarHBondContact O-N 2.98Å
509C93.5Very high90.4Very high2 Ų245 Ų451%0.01426%0.258CS..Hα-helixtrans-62.7-41.8174.3-69.20000112.7L505 A506 S507 L511 L512 K513 T547 M551 L559L505-C509 WeakPolarHBondContact O-CB 3.48Å; L505-C509 PolarHBondContact O-N 3.34Å; L505-C509 PolarHBondContact O-SG 3.47Å; A506-C509 WeakPolarHBondContact O-CB 3.38Å; A506-C509 PolarHBondContact O-N 3.36Å; S507-C509 VanDerWaalsContact C-N 3.34Å; S507-C509 PolarHBondContact O-N 3.34Å; C509-L511 VanDerWaalsContact C-N 3.3Å; C509-L511 PolarHBondContact O-N 2.68Å; C509-L512 PolarHBondContact O-N 2.93Å; C509-K513 VanDerWaalsContact O-CB 3.32Å; C509-K513 WeakPolarHBondContact O-CB 3.45Å; C509-K513 PolarHBondContact O-N 3.15Å; C509-T547 WeakPolarHBondContact SG-CG2 2.99Å; C509-M551 HydrophobicContact CB-CE 4.08Å; C509-M551 HydrophobicContact CB-CG 4.29Å; C509-M551 HydrophobicContact CB-SD 4.36Å; C509-L559 HydrophobicContact CB-CD1 4.02Å; C509-L559 HydrophobicContact CB-CD2 3.64Å
510A92.1Very high90.3Very high52 Ų5246.1 Ų46.143%0.4326%0.263SS..Hα-helixtrans-62.1-40.6176.600000111.3A506 S507 N508 K514 L559A506-A510 PolarHBondContact O-N 3.36Å; S507-A510 PolarHBondContact O-N 3.01Å; N508-A510 PolarHBondContact O-N 3.13Å; A510-K514 PolarHBondContact O-N 3.01Å; A510-K514 VanDerWaalsContact O-N 3.13Å; A510-L559 HydrophobicContact CB-CD1 4.23Å
511L91.3Very high90.3Very high30 Ų3046.4 Ų46.416%0.15727%0.267CS..Hα-helixtrans-69.4-44.1176.1-172.555.4000112.2L467 S507 N508 C509 K513 K514 L515L467-L511 HydrophobicContact CD1-CB 4.32Å; L467-L511 HydrophobicContact CD1-CD2 3.96Å; L467-L511 HydrophobicContact CD1-CG 3.79Å; L467-L511 HydrophobicContact CG-CD2 3.89Å; L467-L511 HydrophobicContact CG-CG 4.2Å; L467-L511 WeakPolarHBondContact O-CD2 3.49Å; S507-L511 PolarHBondContact O-N 3.45Å; N508-L511 PolarHBondContact O-N 3.41Å; C509-L511 VanDerWaalsContact C-N 3.3Å; C509-L511 PolarHBondContact O-N 2.68Å; L511-K513 VanDerWaalsContact C-N 3.32Å; L511-K513 PolarHBondContact O-N 2.76Å; L511-K514 WeakPolarHBondContact O-CB 3.18Å; L511-K514 PolarHBondContact O-N 2.6Å; L511-K514 VanDerWaalsContact O-N 3.11Å; L511-L515 HydrophobicContact CD1-CD1 3.86Å; L511-L515 HydrophobicContact CD1-CG 4.01Å; L511-L515 HydrophobicContact CG-CD1 3.87Å; L511-L515 HydrophobicContact CG-CG 4.38Å; L511-L515 WeakPolarHBondContact O-CG 3.4Å; L511-L515 PolarHBondContact O-N 2.95Å
512L92.6Very high90.4Very high5 Ų548.1 Ų48.13%0.02628%0.275CS..Hα-helixtrans-55.9-46173-76.3171.5000111.3L467 L488 L490 N508 C509 K514 L515 S516 T524L467-L512 HydrophobicContact CD1-CD2 3.84Å; L467-L512 HydrophobicContact CD1-CG 4.17Å; L467-L512 HydrophobicContact CD2-CD1 4.39Å; L467-L512 HydrophobicContact CD2-CD2 4Å; L467-L512 HydrophobicContact CD2-CG 3.74Å; L488-L512 HydrophobicContact CB-CD2 3.89Å; L488-L512 HydrophobicContact CD1-CD2 3.74Å; L488-L512 HydrophobicContact CG-CD2 4.48Å; L490-L512 HydrophobicContact CD1-CD1 4.3Å; L490-L512 HydrophobicContact CD2-CD1 4.3Å; N508-L512 WeakPolarHBondContact O-CB 3.42Å; N508-L512 WeakPolarHBondContact O-CG 3.48Å; N508-L512 PolarHBondContact O-N 2.98Å; C509-L512 PolarHBondContact O-N 2.93Å; L512-K514 VanDerWaalsContact C-N 3.26Å; L512-K514 PolarHBondContact O-N 2.96Å; L512-L515 PolarHBondContact O-N 2.61Å; L512-S516 WeakPolarHBondContact O-CB 3.5Å; L512-S516 PolarHBondContact O-N 2.8Å; L512-S516 PolarHBondContact O-OG 3.3Å; L512-T524 HydrophobicContact CD1-CG2 4.38Å; L512-T524 HydrophobicContact CD2-CG2 4.02Å
513K91.9Very high90.4Very high52 Ų5246.4 Ų46.423%0.22626%0.261CS..Hα-helixtrans-62.7-31.8177.9-175.8167.6-169167.70112.9C509 L511 S516 M551 C555 Q556 V557C509-K513 VanDerWaalsContact O-CB 3.32Å; C509-K513 WeakPolarHBondContact O-CB 3.45Å; C509-K513 PolarHBondContact O-N 3.15Å; L511-K513 VanDerWaalsContact C-N 3.32Å; L511-K513 PolarHBondContact O-N 2.76Å; K513-S516 PolarHBondContact O-OG 3.32Å; K513-M551 HydrophobicContact CB-CE 4.02Å; K513-C555 VanDerWaalsContact CD-O 3.23Å; K513-C555 WeakPolarHBondContact CD-O 3.33Å; K513-C555 WeakPolarHBondContact CE-O 3.14Å; K513-C555 VanDerWaalsContact CG-O 3.29Å; K513-C555 WeakPolarHBondContact CG-O 3.45Å; K513-Q556 PolarHBondContact NZ-O 2.84Å; K513-V557 PolarHBondContact NZ-O 2.82Å
514K89.8Confident90.7Very high117 Ų11739.6 Ų39.651%0.50923%0.229SC..Hα-helixtrans-73.6-48.9175.5-176.9-176.8174.9-168.50111A510 L511 L512A510-K514 PolarHBondContact O-N 3.01Å; A510-K514 VanDerWaalsContact O-N 3.13Å; L511-K514 WeakPolarHBondContact O-CB 3.18Å; L511-K514 PolarHBondContact O-N 2.6Å; L511-K514 VanDerWaalsContact O-N 3.11Å; L512-K514 VanDerWaalsContact C-N 3.26Å; L512-K514 PolarHBondContact O-N 2.96Å
515L88.7Confident90.9Very high5 Ų538.7 Ų38.73%0.02623%0.225CC..Hα-helixtrans-78.6-25-173.7-63.5176.9000113.3L467 L470 Q476 L479 L488 L511 L512 K517 L518L467-L515 HydrophobicContact CD1-CD1 3.81Å; L470-L515 HydrophobicContact CB-CD1 3.79Å; L470-L515 HydrophobicContact CD1-CD1 4.01Å; Q476-L515 HydrophobicContact CG-CD2 4.17Å; L479-L515 HydrophobicContact CD2-CD2 4.4Å; L488-L515 HydrophobicContact CD1-CB 3.67Å; L488-L515 HydrophobicContact CD1-CD1 4.36Å; L488-L515 HydrophobicContact CD2-CB 4.46Å; L488-L515 HydrophobicContact CD2-CD1 4.22Å; L511-L515 HydrophobicContact CD1-CD1 3.86Å; L511-L515 HydrophobicContact CD1-CG 4.01Å; L511-L515 HydrophobicContact CG-CD1 3.87Å; L511-L515 HydrophobicContact CG-CG 4.38Å; L511-L515 WeakPolarHBondContact O-CG 3.4Å; L511-L515 PolarHBondContact O-N 2.95Å; L512-L515 PolarHBondContact O-N 2.61Å; L515-K517 PolarHBondContact O-N 2.84Å; L515-K517 VanDerWaalsContact O-N 3.08Å; L515-L518 HydrophobicContact CB-CD1 4.41Å; L515-L518 HydrophobicContact CD2-CD1 3.96Å; L515-L518 VanDerWaalsContact O-CB 3.3Å; L515-L518 WeakPolarHBondContact O-CB 3.41Å; L515-L518 VanDerWaalsContact O-CG 3.31Å; L515-L518 WeakPolarHBondContact O-CG 3.25Å; L515-L518 PolarHBondContact O-N 2.95Å
516S88.1Confident91Very high24 Ų2438.6 Ų38.617%0.16822%0.224CC..THydrogen-bonded Turntrans-62.5-15.8175.566.50000113.9L512 K513 L518L512-S516 WeakPolarHBondContact O-CB 3.5Å; L512-S516 PolarHBondContact O-N 2.8Å; L512-S516 PolarHBondContact O-OG 3.3Å; K513-S516 PolarHBondContact O-OG 3.32Å; S516-L518 VanDerWaalsContact C-N 3.27Å
517K85.7Confident91.1Very high157 Ų15737.2 Ų37.268%0.68321%0.213SC*.THydrogen-bonded Turntrans-77.9-10.7175.4-62.3-179.3-179.2-179.40113.2L515L515-K517 PolarHBondContact O-N 2.84Å; L515-K517 VanDerWaalsContact O-N 3.08Å
518L83.9Confident91.1Very high55 Ų5533.7 Ų33.729%0.28819%0.188SC..SBendtrans-71.9136.8178-63.9171.4000110.3L479 L515 S516 N520 C521L479-L518 HydrophobicContact CD2-CD1 3.34Å; L479-L518 HydrophobicContact CG-CD1 3.87Å; L515-L518 HydrophobicContact CB-CD1 4.41Å; L515-L518 HydrophobicContact CD2-CD1 3.96Å; L515-L518 VanDerWaalsContact O-CB 3.3Å; L515-L518 WeakPolarHBondContact O-CB 3.41Å; L515-L518 VanDerWaalsContact O-CG 3.31Å; L515-L518 WeakPolarHBondContact O-CG 3.25Å; L515-L518 PolarHBondContact O-N 2.95Å; S516-L518 VanDerWaalsContact C-N 3.27Å; L518-N520 VanDerWaalsContact C-N 3.25Å; L518-N520 PolarHBondContact O-N 2.95Å; L518-C521 HydrophobicContact CB-CB 4.33Å; L518-C521 WeakPolarHBondContact O-CB 3.33Å; L518-C521 PolarHBondContact O-N 2.99Å; L518-C521 VanDerWaalsContact O-N 3.12Å
519A75.7Confident90.9Very high96 Ų9634.6 Ų34.679%0.79319%0.19SC*.THydrogen-bonded Turntrans-64.6-27.4-172.100000113.9
520N87.7Confident90.3Very high27 Ų2735.7 Ų35.714%0.14420%0.198CC..THydrogen-bonded Turntrans-89-5.1178.861.5-12.5000113.6L479 V482 P485 V486 L518 L522L479-N520 PolarHBondContact O-ND2 3.4Å; V482-N520 PolarHBondContact O-ND2 3.41Å; P485-N520 WeakPolarHBondContact CA-O 3.41Å; V486-N520 PolarHBondContact N-O 3.31Å; L518-N520 VanDerWaalsContact C-N 3.25Å; L518-N520 PolarHBondContact O-N 2.95Å; N520-L522 PolarHBondContact O-N 3.49Å; N520-L522 VanDerWaalsContact O-N 3.15Å
521C91.2Very high89.3Confident20 Ų2035.6 Ų35.614%0.13519%0.192CC..EExtended strand (participates in β ladder)trans-75.6102.9-179.8-178.40000110.9V486 L518V486-C521 CarbonylContact O-C 3.55Å; V486-C521 WeakPolarHBondContact O-CA 3.31Å; L518-C521 HydrophobicContact CB-CB 4.33Å; L518-C521 WeakPolarHBondContact O-CB 3.33Å; L518-C521 PolarHBondContact O-N 2.99Å; L518-C521 VanDerWaalsContact O-N 3.12Å
522L93.9Very high88.4Confident42 Ų4236.4 Ų36.422%0.2221%0.208CC..EExtended strand (participates in β ladder)trans-82-29.2177.7-69.2-169000113.7R307 I308 V462 P485 V486 N520R307-L522 PolarHBondContact N-O 3.43Å; I308-L522 HydrophobicContact CD1-CB 4Å; I308-L522 HydrophobicContact CD1-CD1 4.09Å; I308-L522 HydrophobicContact CG1-CB 4.49Å; I308-L522 PolarHBondContact N-O 3.33Å; V462-L522 HydrophobicContact CG1-CD1 4.27Å; V462-L522 HydrophobicContact CG2-CD1 3.96Å; P485-L522 HydrophobicContact CB-CD1 3.32Å; P485-L522 HydrophobicContact CB-CD2 4.43Å; P485-L522 HydrophobicContact CB-CG 3.6Å; P485-L522 HydrophobicContact CG-CD1 4.22Å; V486-L522 PolarHBondContact O-N 3.31Å; N520-L522 PolarHBondContact O-N 3.49Å; N520-L522 VanDerWaalsContact O-N 3.15Å
523G95.3Very high87.9Confident0 Ų036.2 Ų36.20%021%0.207CC..EExtended strand (participates in β ladder)trans175.1-164.7-178.200000118.4I308 C487 L488I308-G523 CarbonylContact O-C 3.53Å; I308-G523 WeakPolarHBondContact O-CA 3.49Å; C487-G523 CarbonylContact C-O 3.56Å; C487-G523 VanDerWaalsContact CA-O 3.27Å; C487-G523 WeakPolarHBondContact CA-O 3.35Å; L488-G523 PolarHBondContact N-O 3.23Å
524T96.8Very high87.6Confident3 Ų334.4 Ų34.42%0.01820%0.199CC..EExtended strand (participates in β ladder)trans-129.8139.8-174.6-57.20000110.3Q306 I308 A310 L488 L490 L512Q306-T524 VanDerWaalsContact CD-OG1 3.29Å; Q306-T524 PolarHBondContact NE2-OG1 3.02Å; Q306-T524 VanDerWaalsContact NE2-OG1 3.17Å; Q306-T524 VanDerWaalsContact OE1-CB 3.3Å; Q306-T524 PolarHBondContact OE1-OG1 3.41Å; I308-T524 PolarHBondContact O-N 3.43Å; A310-T524 PolarHBondContact N-O 2.98Å; L488-T524 CarbonylContact O-C 3.11Å; L488-T524 VanDerWaalsContact O-CA 3.27Å; L488-T524 WeakPolarHBondContact O-CA 3.29Å; L490-T524 HydrophobicContact CD2-CG2 3.21Å; L512-T524 HydrophobicContact CD1-CG2 4.38Å; L512-T524 HydrophobicContact CD2-CG2 4.02Å
525V97.5Very high87.6Confident0 Ų029.1 Ų29.10%018%0.176CC..EExtended strand (participates in β ladder)trans-120.3114.7175.6-169.70000108.9A310 L312 I464 C487 L488 S489 L490A310-V525 HydrophobicContact CB-CB 4.26Å; A310-V525 HydrophobicContact CB-CG1 4Å; A310-V525 HydrophobicContact CB-CG2 3.98Å; A310-V525 WeakPolarHBondContact O-CA 3.22Å; L312-V525 HydrophobicContact CB-CG1 3.96Å; I464-V525 HydrophobicContact CD1-CG2 4.19Å; C487-V525 HydrophobicContact CB-CG2 3.96Å; L488-V525 PolarHBondContact O-N 3.21Å; S489-V525 CarbonylContact C-O 3.23Å; S489-V525 VanDerWaalsContact CA-O 3.27Å; S489-V525 WeakPolarHBondContact CA-O 3.43Å; L490-V525 PolarHBondContact N-O 3.27Å
526I96.8Very high87.7Confident2 Ų229.5 Ų29.51%0.0118%0.179CC..EExtended strand (participates in β ladder)trans-86.3121.3169.4178.965.7000109A310 L311 L312 L490 P544 A545 A548A310-I526 WeakPolarHBondContact O-CG2 3.45Å; A310-I526 PolarHBondContact O-N 2.94Å; L311-I526 WeakPolarHBondContact CA-O 3.46Å; L311-I526 HydrophobicContact CB-CG2 4.35Å; L311-I526 HydrophobicContact CD1-CG2 3.84Å; L312-I526 PolarHBondContact N-O 3.47Å; L490-I526 HydrophobicContact CD1-CD1 4.08Å; L490-I526 HydrophobicContact CG-CD1 3.8Å; I526-P544 HydrophobicContact CD1-CB 3.8Å; I526-A545 HydrophobicContact CG1-CB 4.47Å; I526-A545 HydrophobicContact CG2-CB 4.45Å; I526-A548 HydrophobicContact CB-CB 3.87Å; I526-A548 HydrophobicContact CD1-CB 4.36Å; I526-A548 HydrophobicContact CG1-CB 4.35Å; I526-A548 HydrophobicContact CG2-CB 4.4Å
527C94.8Very high87.9Confident0 Ų029.1 Ų29.10%018%0.176CC..EExtended strand (participates in β ladder)trans-106.3116.7-174.6-58.50000111.6L312 L490 R491 S492 Y529L312-C527 HydrophobicContact CB-CB 4.32Å; L312-C527 HydrophobicContact CD2-CB 4.26Å; L490-C527 PolarHBondContact O-N 2.95Å; R491-C527 CarbonylContact C-O 3.57Å; R491-C527 WeakPolarHBondContact CA-O 3.42Å; S492-C527 PolarHBondContact N-O 3.15Å; S492-C527 PolarHBondContact OG-O 3.49Å; C527-Y529 HydrophobicContact CB-CD2 3.6Å; C527-Y529 HydrophobicContact CB-CE1 4.44Å; C527-Y529 HydrophobicContact CB-CE2 3.16Å; C527-Y529 HydrophobicContact CB-CG 4.41Å; C527-Y529 PolarHBondContact O-N 2.81Å
528D93.3Very high88.1Confident2 Ų221.9 Ų21.91%0.01115%0.145CC..EExtended strand (participates in β ladder)trans-95.175172.6-1672000109.9L312 L313 D314 R319 H538 S541L312-D528 PolarHBondContact O-N 2.8Å; L313-D528 HydrophobicContact CD2-CB 4.28Å; D314-D528 WeakPolarHBondContact CB-O 3.37Å; D314-D528 PolarHBondContact N-O 2.78Å; R319-D528 IonicContact CZ-OD1 2.81Å; R319-D528 IonicContact NH1-OD1 3.56Å; R319-D528 PolarHBondContact NH1-OD1 2.87Å; R319-D528 PolarHBondContact NH2-O 2.77Å; R319-D528 VanDerWaalsContact NH2-O 3.07Å; R319-D528 IonicContact NH2-OD1 3.33Å; R319-D528 PolarHBondContact NH2-OD1 2.87Å; R319-D528 IonicContact NH2-OD2 2.89Å; D528-H538 IonicContact OD2-CE1 3.09Å; D528-H538 IonicContact OD2-ND1 2.81Å; D528-H538 PolarHBondContact OD2-ND1 3.39Å; D528-S541 VanDerWaalsContact OD2-CB 3.32Å; D528-S541 WeakPolarHBondContact OD2-CB 3.3Å; D528-S541 PolarHBondContact OD2-OG 3.14Å
529Y89.1Confident88.6Confident35 Ų3519.3 Ų19.314%0.13713%0.131CC..  trans-69.8150.1-179.8-70.5-68.6000112.5L312 D314 R319 R491 C527 T531L312-Y529 HydrophobicContact CD2-CD1 4.4Å; L312-Y529 HydrophobicContact CD2-CE1 4.02Å; D314-Y529 HydrophobicContact CB-CD1 3.99Å; R319-Y529 PolarHBondContact NH2-O 3.28Å; R491-Y529 HydrophobicContact CG-CD2 3.86Å; R491-Y529 HydrophobicContact CG-CE2 3.92Å; C527-Y529 HydrophobicContact CB-CD2 3.6Å; C527-Y529 HydrophobicContact CB-CE1 4.44Å; C527-Y529 HydrophobicContact CB-CE2 3.16Å; C527-Y529 HydrophobicContact CB-CG 4.41Å; C527-Y529 PolarHBondContact O-N 2.81Å; Y529-T531 PolarHBondContact O-N 2.86Å
530S79.8Confident89.5Confident25 Ų2515.1 Ų15.118%0.17510%0.095CC..  trans-70.7128.8163.4-1790000109.4D314 G532 E534D314-S530 PolarHBondContact OD2-N 3.18Å; S530-G532 VanDerWaalsContact C-N 3.3Å; S530-G532 PolarHBondContact OG-N 3.37Å; S530-E534 PolarHBondContact OG-OE1 3.21Å
531T71.6Confident89.7Confident50 Ų5014 Ų1431%0.3079%0.089SC..  trans-86.7-2.8178.7590000112.7Y529 C533Y529-T531 PolarHBondContact O-N 2.86Å; T531-C533 PolarHBondContact O-N 3.06Å; T531-C533 PolarHBondContact OG1-N 2.78Å; T531-C533 PolarHBondContact OG1-O 2.87Å
532G72.6Confident89.9Confident47 Ų4713.1 Ų13.149%0.4858%0.084SC..SBendtrans72.9-6.5-166.700000113.9S530S530-G532 VanDerWaalsContact C-N 3.3Å; S530-G532 PolarHBondContact OG-N 3.37Å
533C82.6Confident90Very high2 Ų211.3 Ų11.31%0.0147%0.074CC..  trans-10390.1169.5-166.80000109.1F498 T531 I535 V536 M756F498-C533 HydrophobicContact CE1-CB 4.22Å; F498-C533 VanDerWaalsContact CE1-SG 3.56Å; T531-C533 PolarHBondContact O-N 3.06Å; T531-C533 PolarHBondContact OG1-N 2.78Å; T531-C533 PolarHBondContact OG1-O 2.87Å; C533-I535 PolarHBondContact O-N 2.93Å; C533-V536 WeakPolarHBondContact O-CG2 3.47Å; C533-V536 PolarHBondContact O-N 3.01Å; C533-V536 VanDerWaalsContact O-N 3.09Å; C533-M756 HydrophobicContact CB-SD 4.45Å; C533-M756 PolarHBondContact SG-SD 3.03Å
534E85Confident90Very high14 Ų1411.4 Ų11.47%0.0658%0.075CC..THydrogen-bonded Turntrans-65.9-2.7-169.6-56.7-63.6168.200114.5C318 R319 S530 V536 F737 W741 A753 M756C318-E534 VanDerWaalsContact CB-CD 3.45Å; C318-E534 HydrophobicContact CB-CG 3.88Å; C318-E534 WeakPolarHBondContact CB-OE1 3.21Å; C318-E534 PolarHBondContact N-OE1 3.32Å; C318-E534 PolarHBondContact SG-OE1 3.01Å; R319-E534 WeakPolarHBondContact CB-OE2 3.35Å; R319-E534 PolarHBondContact N-OE2 3.42Å; S530-E534 PolarHBondContact OG-OE1 3.21Å; E534-V536 PolarHBondContact O-N 3.38Å; E534-F737 HydrophobicContact CB-CZ 4.48Å; E534-F737 VanDerWaalsContact O-CE2 3.31Å; E534-F737 WeakPolarHBondContact O-CE2 3.24Å; E534-F737 WeakPolarHBondContact O-CZ 3.49Å; E534-W741 HydrophobicContact CB-CH2 4.1Å; E534-W741 HydrophobicContact CB-CZ3 4Å; E534-W741 WeakPolarHBondContact O-CZ3 3.44Å; E534-A753 HydrophobicContact CB-CB 4.03Å; E534-A753 HydrophobicContact CG-CB 4.31Å; E534-M756 HydrophobicContact CB-CE 4.27Å
535I89.7Confident90Very high5 Ų511.3 Ų11.33%0.0267%0.074CC..THydrogen-bonded Turntrans-71.1-21171.3-158.6172000112.3F498 C533 P537 V681 M684 F737 M756 F757F498-I535 HydrophobicContact CE1-CG2 4.18Å; C533-I535 PolarHBondContact O-N 2.93Å; I535-P537 WeakPolarHBondContact O-CD 3.4Å; I535-V681 HydrophobicContact CG1-CG2 4.4Å; I535-M684 HydrophobicContact CD1-CB 3.34Å; I535-M684 HydrophobicContact CD1-CG 3.51Å; I535-F737 HydrophobicContact CG1-CD2 4.25Å; I535-F737 HydrophobicContact CG1-CE2 4.46Å; I535-M756 HydrophobicContact CB-CE 4.21Å; I535-F757 HydrophobicContact CD1-CZ 4.05Å; I535-F757 HydrophobicContact CG1-CZ 4.34Å
536V91.6Very high89.9Confident14 Ų1411.3 Ų11.39%0.0857%0.074CC..  trans-68.8107.4-177.2179.20000110.6R319 F498 C533 E534 L540R319-V536 PolarHBondContact NH1-O 3.4Å; F498-V536 HydrophobicContact CB-CG2 4.27Å; F498-V536 HydrophobicContact CD1-CG2 3.46Å; F498-V536 VanDerWaalsContact CD1-CG2 3.46Å; F498-V536 HydrophobicContact CE1-CG2 4.25Å; F498-V536 HydrophobicContact CG-CG2 4.27Å; C533-V536 WeakPolarHBondContact O-CG2 3.47Å; C533-V536 PolarHBondContact O-N 3.01Å; C533-V536 VanDerWaalsContact O-N 3.09Å; E534-V536 PolarHBondContact O-N 3.38Å; V536-L540 HydrophobicContact CG1-CD1 4.37Å
537P92.1Very high89.9Confident16 Ų1611.3 Ų11.310%0.1047%0.074CC..  trans-83.1162.6-176.936.5-34.2000111.2I535 S539 L540 E677 V681I535-P537 WeakPolarHBondContact O-CD 3.4Å; P537-S539 PolarHBondContact O-N 3.4Å; P537-L540 HydrophobicContact CG-CD1 4.37Å; P537-L540 HydrophobicContact CG-CG 3.94Å; P537-L540 PolarHBondContact O-N 3.45Å; P537-E677 HydrophobicContact CB-CB 3.67Å; P537-E677 HydrophobicContact CB-CG 3.85Å; P537-E677 HydrophobicContact CG-CB 3.83Å; P537-V681 HydrophobicContact CG-CG2 4.23Å
538H90.2Very high89.9Confident5 Ų511.4 Ų11.42%0.0238%0.075CC..G310 helixtrans-57.8-31.9173.5-172.954.9000112.3Y321 I329 D528 L540 S541 F542Y321-H538 HydrophobicContact CE1-CB 4.38Å; Y321-H538 WeakPolarHBondContact OH-CB 3.4Å; I329-H538 WeakPolarHBondContact CG1-NE2 3.42Å; D528-H538 IonicContact OD2-CE1 3.09Å; D528-H538 IonicContact OD2-ND1 2.81Å; D528-H538 PolarHBondContact OD2-ND1 3.39Å; H538-L540 PolarHBondContact O-N 2.91Å; H538-S541 PolarHBondContact CE1-OG 3.17Å; H538-S541 VanDerWaalsContact CE1-OG 3.27Å; H538-S541 PolarHBondContact ND1-OG 3.27Å; H538-S541 VanDerWaalsContact ND1-OG 3.16Å; H538-S541 PolarHBondContact O-N 3.15Å; H538-S541 PolarHBondContact O-OG 2.88Å; H538-F542 AromaticContact CD2-CE1 3.39Å; H538-F542 WeakPolarHBondContact CD2-CE1 3.49Å; H538-F542 AromaticContact NE2-CE1 3.46Å; H538-F542 WeakPolarHBondContact NE2-CE1 3.43Å
539S92.7Very high90.1Very high1 Ų111.4 Ų11.41%0.0078%0.075CC..G310 helixtrans-56.7-22.5-179.9-64.90000114.1P537 F542 C674 E677P537-S539 PolarHBondContact O-N 3.4Å; S539-F542 WeakPolarHBondContact O-CB 3.29Å; S539-F542 WeakPolarHBondContact O-CD2 3.37Å; S539-F542 WeakPolarHBondContact O-CG 3.39Å; S539-C674 WeakPolarHBondContact OG-CB 3.34Å; S539-C674 PolarHBondContact OG-SG 3.49Å; S539-C674 VanDerWaalsContact OG-SG 3.34Å; S539-E677 WeakPolarHBondContact CB-OE2 3.37Å; S539-E677 PolarHBondContact OG-OE2 3.28Å
540L94.4Very high90.4Very high7 Ų79.8 Ų9.84%0.0377%0.069CC..G310 helixtrans-80.2-18175.5-62.2-173000113.8F498 C499 V536 P537 H538 F542 I587 M590 V678 V681F498-L540 HydrophobicContact CB-CD1 4.35Å; F498-L540 WeakPolarHBondContact O-CD1 3.1Å; C499-L540 HydrophobicContact CB-CD1 4.26Å; V536-L540 HydrophobicContact CG1-CD1 4.37Å; P537-L540 HydrophobicContact CG-CD1 4.37Å; P537-L540 HydrophobicContact CG-CG 3.94Å; P537-L540 PolarHBondContact O-N 3.45Å; H538-L540 PolarHBondContact O-N 2.91Å; L540-F542 VanDerWaalsContact C-N 3.31Å; L540-I587 HydrophobicContact CD2-CB 4.47Å; L540-I587 HydrophobicContact CD2-CD1 4Å; L540-I587 HydrophobicContact CD2-CG1 3.79Å; L540-I587 HydrophobicContact CD2-CG2 3.91Å; L540-M590 HydrophobicContact CD1-CE 3.88Å; L540-M590 HydrophobicContact CD2-CE 3.67Å; L540-M590 HydrophobicContact CG-CE 4.47Å; L540-V678 HydrophobicContact CD2-CG2 4.03Å; L540-V681 HydrophobicContact CD1-CG1 4.36Å; L540-V681 HydrophobicContact CD1-CG2 4.2Å
541S93.3Very high91.1Very high3 Ų38.8 Ų8.82%0.0216%0.062CC..THydrogen-bonded Turntrans-84.5-6.2176.570.50000113.6D528 H538 P544 A545D528-S541 VanDerWaalsContact OD2-CB 3.32Å; D528-S541 WeakPolarHBondContact OD2-CB 3.3Å; D528-S541 PolarHBondContact OD2-OG 3.14Å; H538-S541 PolarHBondContact CE1-OG 3.17Å; H538-S541 VanDerWaalsContact CE1-OG 3.27Å; H538-S541 PolarHBondContact ND1-OG 3.27Å; H538-S541 VanDerWaalsContact ND1-OG 3.16Å; H538-S541 PolarHBondContact O-N 3.15Å; H538-S541 PolarHBondContact O-OG 2.88Å; S541-P544 WeakPolarHBondContact O-CD 3.5Å; S541-A545 VanDerWaalsContact O-CB 3.24Å; S541-A545 WeakPolarHBondContact O-CB 3.41Å; S541-A545 PolarHBondContact O-N 3.06Å
542F94.4Very high92.3Very high3 Ų36.4 Ų6.41%0.0135%0.047CC..Hα-helixtrans-58.1-50.2179.1-77-6.9000114.5M333 H538 S539 L540 A545 V546 L574 F584M333-F542 HydrophobicContact CE-CD1 4.41Å; H538-F542 AromaticContact CD2-CE1 3.39Å; H538-F542 WeakPolarHBondContact CD2-CE1 3.49Å; H538-F542 AromaticContact NE2-CE1 3.46Å; H538-F542 WeakPolarHBondContact NE2-CE1 3.43Å; S539-F542 WeakPolarHBondContact O-CB 3.29Å; S539-F542 WeakPolarHBondContact O-CD2 3.37Å; S539-F542 WeakPolarHBondContact O-CG 3.39Å; L540-F542 VanDerWaalsContact C-N 3.31Å; F542-A545 PolarHBondContact O-N 3.35Å; F542-V546 WeakPolarHBondContact O-CB 3.24Å; F542-V546 VanDerWaalsContact O-CG2 3.28Å; F542-V546 WeakPolarHBondContact O-CG2 3.42Å; F542-V546 PolarHBondContact O-N 3.17Å; F542-L574 HydrophobicContact CB-CD1 3.44Å; F542-L574 VanDerWaalsContact CB-CD1 3.44Å; F542-L574 HydrophobicContact CD1-CD1 4.2Å; F542-L574 HydrophobicContact CD2-CD1 3.86Å; F542-L574 HydrophobicContact CG-CD1 3.58Å; F542-F584 HydrophobicContact CB-CE1 3.99Å; F542-F584 HydrophobicContact CD2-CE1 4.06Å; F542-F584 HydrophobicContact CD2-CZ 4.27Å
543L96.2Very high93.4Very high3 Ų34.2 Ų4.22%0.0162%0.024CC..Hα-helixtrans-63.6-48.8-179.3-73.7172.5000112.7A545 T547 L566 A570 F584 I587 L588L543-A545 VanDerWaalsContact C-N 3.33Å; L543-A545 PolarHBondContact O-N 3.08Å; L543-T547 VanDerWaalsContact O-CB 3.32Å; L543-T547 WeakPolarHBondContact O-CB 3.47Å; L543-T547 PolarHBondContact O-N 2.9Å; L543-T547 PolarHBondContact O-OG1 3.46Å; L543-L566 HydrophobicContact CD2-CD1 3.74Å; L543-L566 HydrophobicContact CD2-CD2 4.15Å; L543-L566 HydrophobicContact CD2-CG 3.75Å; L543-A570 HydrophobicContact CD2-CB 3.65Å; L543-F584 HydrophobicContact CD1-CB 4.4Å; L543-F584 HydrophobicContact CD1-CD1 4.27Å; L543-F584 HydrophobicContact CD2-CB 4.11Å; L543-F584 HydrophobicContact CD2-CD1 3.74Å; L543-F584 HydrophobicContact CD2-CG 4.24Å; L543-F584 HydrophobicContact CG-CD1 3.78Å; L543-I587 HydrophobicContact CD1-CB 4.12Å; L543-I587 HydrophobicContact CD1-CG2 3.83Å; L543-L588 HydrophobicContact CD1-CD2 3.77Å; L543-L588 HydrophobicContact CD1-CG 3.81Å
544P95.9Very high94.1Very high3 Ų34.4 Ų4.42%0.0193%0.025CC..Hα-helixtrans-56.2-43.1170.9-22.927.5000113.4S492 L505 I526 S541 T547 A548S492-P544 WeakPolarHBondContact O-CG 3.33Å; L505-P544 HydrophobicContact CD2-CB 4.12Å; L505-P544 HydrophobicContact CD2-CG 4.2Å; I526-P544 HydrophobicContact CD1-CB 3.8Å; S541-P544 WeakPolarHBondContact O-CD 3.5Å; P544-T547 PolarHBondContact O-N 3.08Å; P544-A548 VanDerWaalsContact O-CB 3.27Å; P544-A548 WeakPolarHBondContact O-CB 3.3Å; P544-A548 PolarHBondContact O-N 2.73Å
545A95.9Very high94.4Very high1 Ų14.6 Ų4.61%0.0083%0.028CC..Hα-helixtrans-65.7-47.3-17900000112.6M333 I526 S541 F542 L543 T547 A548 L549M333-A545 HydrophobicContact CE-CB 3.97Å; M333-A545 HydrophobicContact SD-CB 3.93Å; I526-A545 HydrophobicContact CG1-CB 4.47Å; I526-A545 HydrophobicContact CG2-CB 4.45Å; S541-A545 VanDerWaalsContact O-CB 3.24Å; S541-A545 WeakPolarHBondContact O-CB 3.41Å; S541-A545 PolarHBondContact O-N 3.06Å; F542-A545 PolarHBondContact O-N 3.35Å; L543-A545 VanDerWaalsContact C-N 3.33Å; L543-A545 PolarHBondContact O-N 3.08Å; A545-T547 VanDerWaalsContact C-N 3.26Å; A545-T547 PolarHBondContact O-N 2.68Å; A545-A548 PolarHBondContact O-N 3.24Å; A545-L549 VanDerWaalsContact O-CB 3.3Å; A545-L549 WeakPolarHBondContact O-CB 3.39Å; A545-L549 VanDerWaalsContact O-CG 3.29Å; A545-L549 WeakPolarHBondContact O-CG 3.19Å; A545-L549 PolarHBondContact O-N 3.11Å
546V96.1Very high94.5Very high0 Ų09.6 Ų9.60%05%0.051CC..Hα-helixtrans-55.6-45.5174.4168.30000110.4W161 L336 F542 G550 L566 I569 A570 L574W161-V546 PolarHBondContact NE1-O 3.49Å; L336-V546 HydrophobicContact CD1-CG2 3.74Å; F542-V546 WeakPolarHBondContact O-CB 3.24Å; F542-V546 VanDerWaalsContact O-CG2 3.28Å; F542-V546 WeakPolarHBondContact O-CG2 3.42Å; F542-V546 PolarHBondContact O-N 3.17Å; V546-G550 PolarHBondContact O-N 2.79Å; V546-G550 VanDerWaalsContact O-N 3.1Å; V546-L566 HydrophobicContact CG1-CD1 4.28Å; V546-I569 HydrophobicContact CG1-CG2 4.01Å; V546-A570 HydrophobicContact CG2-CB 4.46Å; V546-L574 HydrophobicContact CG2-CD1 3.64Å; V546-L574 HydrophobicContact CG2-CD2 4.26Å; V546-L574 HydrophobicContact CG2-CG 4Å
547T96.3Very high94.5Very high2 Ų29 Ų91%0.0125%0.047CC..Hα-helixtrans-64.6-52.3-179.3-59.30000111.8C509 L543 P544 A545 G550 M551 F562 F563C509-T547 WeakPolarHBondContact SG-CG2 2.99Å; L543-T547 VanDerWaalsContact O-CB 3.32Å; L543-T547 WeakPolarHBondContact O-CB 3.47Å; L543-T547 PolarHBondContact O-N 2.9Å; L543-T547 PolarHBondContact O-OG1 3.46Å; P544-T547 PolarHBondContact O-N 3.08Å; A545-T547 VanDerWaalsContact C-N 3.26Å; A545-T547 PolarHBondContact O-N 2.68Å; T547-G550 PolarHBondContact O-N 2.93Å; T547-M551 WeakPolarHBondContact O-CB 3.14Å; T547-M551 WeakPolarHBondContact O-CG 3.23Å; T547-M551 PolarHBondContact O-N 3.29Å; T547-F562 HydrophobicContact CG2-CE1 3.84Å; T547-F562 HydrophobicContact CG2-CZ 4.35Å; T547-F563 HydrophobicContact CG2-CZ 4.17Å
548A95.8Very high94.5Very high2 Ų212.1 Ų12.12%0.0176%0.063CC..Hα-helixtrans-64.9-48.5-176.600000112.7L490 I526 P544 A545 G550 M551 A552L490-A548 HydrophobicContact CD1-CB 4.05Å; L490-A548 HydrophobicContact CD2-CB 4.08Å; L490-A548 HydrophobicContact CG-CB 4.47Å; I526-A548 HydrophobicContact CB-CB 3.87Å; I526-A548 HydrophobicContact CD1-CB 4.36Å; I526-A548 HydrophobicContact CG1-CB 4.35Å; I526-A548 HydrophobicContact CG2-CB 4.4Å; P544-A548 VanDerWaalsContact O-CB 3.27Å; P544-A548 WeakPolarHBondContact O-CB 3.3Å; P544-A548 PolarHBondContact O-N 2.73Å; A545-A548 PolarHBondContact O-N 3.24Å; A548-G550 VanDerWaalsContact C-N 3.31Å; A548-G550 PolarHBondContact O-N 3.39Å; A548-M551 PolarHBondContact O-N 3.17Å; A548-A552 VanDerWaalsContact O-CB 3.31Å; A548-A552 WeakPolarHBondContact O-CB 3.29Å; A548-A552 PolarHBondContact O-N 3.3Å
549L96.6Very high94.5Very high2 Ų213.2 Ų13.21%0.017%0.069CC..Hα-helixtrans-65.6-37.5-179.6-66.9173.4000111.3R309 M333 L336 A338 A545 A552 W553R309-L549 HydrophobicContact CB-CD2 4.18Å; M333-L549 HydrophobicContact CB-CD1 4.37Å; M333-L549 HydrophobicContact SD-CD1 3.76Å; L336-L549 HydrophobicContact CB-CB 4.43Å; L336-L549 HydrophobicContact CB-CD1 3.95Å; L336-L549 HydrophobicContact CD1-CD1 4.22Å; A338-L549 HydrophobicContact CB-CD1 3.98Å; A338-L549 HydrophobicContact CB-CD2 3.8Å; A545-L549 VanDerWaalsContact O-CB 3.3Å; A545-L549 WeakPolarHBondContact O-CB 3.39Å; A545-L549 VanDerWaalsContact O-CG 3.29Å; A545-L549 WeakPolarHBondContact O-CG 3.19Å; A545-L549 PolarHBondContact O-N 3.11Å; L549-A552 PolarHBondContact O-N 3Å; L549-W553 PolarHBondContact O-N 3.29Å
550G95.6Very high94.5Very high0 Ų020 Ų200%011%0.105CC..Hα-helixtrans-63-47.2174.300000112.9V546 T547 A548 A552 W553 N554V546-G550 PolarHBondContact O-N 2.79Å; V546-G550 VanDerWaalsContact O-N 3.1Å; T547-G550 PolarHBondContact O-N 2.93Å; A548-G550 VanDerWaalsContact C-N 3.31Å; A548-G550 PolarHBondContact O-N 3.39Å; G550-A552 VanDerWaalsContact C-N 3.31Å; G550-A552 PolarHBondContact O-N 2.84Å; G550-W553 PolarHBondContact O-N 2.97Å; G550-N554 PolarHBondContact O-N 3.03Å
551M95Very high94.2Very high5 Ų522 Ų223%0.02511%0.114CC..Hα-helixtrans-64.3-34.8175.9-73.9-63.5-66.700112.9C509 K513 T547 A548 W553 N554 C555 V557 L559C509-M551 HydrophobicContact CB-CE 4.08Å; C509-M551 HydrophobicContact CB-CG 4.29Å; C509-M551 HydrophobicContact CB-SD 4.36Å; K513-M551 HydrophobicContact CB-CE 4.02Å; T547-M551 WeakPolarHBondContact O-CB 3.14Å; T547-M551 WeakPolarHBondContact O-CG 3.23Å; T547-M551 PolarHBondContact O-N 3.29Å; A548-M551 PolarHBondContact O-N 3.17Å; M551-W553 VanDerWaalsContact C-N 3.34Å; M551-N554 CarbonylContact O-C 3.59Å; M551-N554 VanDerWaalsContact O-C 3.23Å; M551-C555 WeakPolarHBondContact O-CA 3.33Å; M551-C555 PolarHBondContact O-N 3Å; M551-V557 HydrophobicContact SD-CB 4.17Å; M551-L559 HydrophobicContact CE-CD2 4.05Å; M551-L559 HydrophobicContact SD-CD2 3.77Å
552A95.8Very high94.2Very high0 Ų022.1 Ų22.10%012%0.115CC..Hα-helixtrans-69.1-34176.500000112Q306 R309 A548 L549 G550Q306-A552 HydrophobicContact CB-CB 4.46Å; Q306-A552 WeakPolarHBondContact CB-O 3.29Å; Q306-A552 PolarHBondContact N-O 3.47Å; Q306-A552 VanDerWaalsContact OE1-CA 3.27Å; R309-A552 HydrophobicContact CB-CB 4.4Å; R309-A552 HydrophobicContact CG-CB 3.78Å; A548-A552 VanDerWaalsContact O-CB 3.31Å; A548-A552 WeakPolarHBondContact O-CB 3.29Å; A548-A552 PolarHBondContact O-N 3.3Å; L549-A552 PolarHBondContact O-N 3Å; G550-A552 VanDerWaalsContact C-N 3.31Å; G550-A552 PolarHBondContact O-N 2.84Å
553W96.7Very high94.2Very high0 Ų023.7 Ų23.70%012%0.121CC..Hα-helixtrans-73.4-50.5171.9-174.5-88.7000112P162 Q165 Y250 Y271 D302 P304 S305 K337 L549 G550 M551P162-W553 HydrophobicContact CB-CB 3.5Å; P162-W553 VanDerWaalsContact CB-CB 3.5Å; P162-W553 HydrophobicContact CB-CG 3.56Å; P162-W553 HydrophobicContact CG-CB 3.78Å; P162-W553 HydrophobicContact CG-CG 3.97Å; Q165-W553 PolarHBondContact NE2-O 3.23Å; Y250-W553 HydrophobicContact CE1-CH2 4.28Å; Y250-W553 AromaticContact CE1-CZ2 3.91Å; Y250-W553 HydrophobicContact CE1-CZ2 3.91Å; Y271-W553 AromaticContact CD2-CH2 3.54Å; Y271-W553 HydrophobicContact CD2-CH2 3.54Å; Y271-W553 AromaticContact CD2-CZ3 3.63Å; Y271-W553 HydrophobicContact CD2-CZ3 3.63Å; Y271-W553 HydrophobicContact CE2-CH2 4.17Å; Y271-W553 AromaticContact CE2-CZ3 3.83Å; Y271-W553 HydrophobicContact CE2-CZ3 3.83Å; Y271-W553 AromaticContact CG-CH2 3.97Å; Y271-W553 HydrophobicContact CG-CH2 3.97Å; Y271-W553 HydrophobicContact CG-CZ3 4.11Å; D302-W553 HydrophobicContact CB-CZ2 4.42Å; D302-W553 PolarHBondContact OD1-NE1 3.25Å; D302-W553 WeakPolarHBondContact OD2-CZ2 3.49Å; D302-W553 PolarHBondContact OD2-NE1 3.37Å; P304-W553 HydrophobicContact CB-CD2 4.32Å; P304-W553 HydrophobicContact CB-CE3 3.75Å; P304-W553 HydrophobicContact CB-CH2 4.31Å; P304-W553 HydrophobicContact CB-CZ3 3.74Å; P304-W553 HydrophobicContact CG-CH2 4.42Å; P304-W553 HydrophobicContact CG-CZ3 4.15Å; S305-W553 VanDerWaalsContact CB-O 3.31Å; S305-W553 WeakPolarHBondContact CB-O 3.39Å; S305-W553 PolarHBondContact N-O 3.01Å; S305-W553 PolarHBondContact OG-O 2.84Å; K337-W553 HydrophobicContact CB-CD2 4.42Å; K337-W553 HydrophobicContact CB-CE3 3.68Å; K337-W553 HydrophobicContact CB-CZ3 3.87Å; K337-W553 HydrophobicContact CD-CD2 3.53Å; K337-W553 HydrophobicContact CD-CE3 3.44Å; K337-W553 VanDerWaalsContact CD-CE3 3.44Å; K337-W553 HydrophobicContact CD-CG 4.33Å; K337-W553 HydrophobicContact CD-CH2 3.61Å; K337-W553 HydrophobicContact CD-CZ2 3.66Å; K337-W553 HydrophobicContact CD-CZ3 3.49Å; K337-W553 VanDerWaalsContact CD-CZ3 3.49Å; K337-W553 HydrophobicContact CG-CE3 4.23Å; K337-W553 HydrophobicContact CG-CZ3 4.27Å; L549-W553 PolarHBondContact O-N 3.29Å; G550-W553 PolarHBondContact O-N 2.97Å; M551-W553 VanDerWaalsContact C-N 3.34Å
554N95.8Very high94Very high7 Ų726.1 Ų26.14%0.03714%0.139CC..  trans-131.3102.2178.4-175.6-6.4000110.8Q163 P164 S305 G550 M551 Q556 V557Q163-N554 WeakPolarHBondContact O-CB 3.4Å; Q163-N554 PolarHBondContact O-ND2 2.85Å; P164-N554 PolarHBondContact O-ND2 2.73Å; S305-N554 WeakPolarHBondContact OG-CA 3.43Å; G550-N554 PolarHBondContact O-N 3.03Å; M551-N554 CarbonylContact O-C 3.59Å; M551-N554 VanDerWaalsContact O-C 3.23Å; N554-Q556 VanDerWaalsContact C-N 3.26Å; N554-Q556 PolarHBondContact O-N 3.23Å; N554-Q556 PolarHBondContact OD1-N 3.05Å; N554-V557 HydrophobicContact CB-CG2 4.03Å; N554-V557 WeakPolarHBondContact O-CG2 3.45Å
555C92Very high93.8Very high18 Ų1826.2 Ų26.212%0.12214%0.139CC..THydrogen-bonded Turntrans-79.1-6.6179.564.40000113.9S305 K513 M551S305-C555 PolarHBondContact OG-N 2.75Å; K513-C555 VanDerWaalsContact CD-O 3.23Å; K513-C555 WeakPolarHBondContact CD-O 3.33Å; K513-C555 WeakPolarHBondContact CE-O 3.14Å; K513-C555 VanDerWaalsContact CG-O 3.29Å; K513-C555 WeakPolarHBondContact CG-O 3.45Å; M551-C555 WeakPolarHBondContact O-CA 3.33Å; M551-C555 PolarHBondContact O-N 3Å
556Q91.5Very high93.7Very high109 Ų10926.2 Ų26.251%0.50914%0.139SC..THydrogen-bonded Turntrans-92.92.1-178.8-62.2-54-37.400113.8K513 N554K513-Q556 PolarHBondContact NZ-O 2.84Å; N554-Q556 VanDerWaalsContact C-N 3.26Å; N554-Q556 PolarHBondContact O-N 3.23Å; N554-Q556 PolarHBondContact OD1-N 3.05Å
557V91.7Very high93.6Very high2 Ų226.7 Ų26.71%0.01214%0.142CC..  trans-47.7140176.61750000111.6W161 Q163 K513 M551 N554 L559 F562W161-V557 HydrophobicContact CH2-CG1 4.11Å; W161-V557 HydrophobicContact CH2-CG2 4.27Å; W161-V557 HydrophobicContact CZ3-CG1 4.19Å; W161-V557 HydrophobicContact CZ3-CG2 4.37Å; Q163-V557 HydrophobicContact CB-CG2 3.88Å; K513-V557 PolarHBondContact NZ-O 2.82Å; M551-V557 HydrophobicContact SD-CB 4.17Å; N554-V557 HydrophobicContact CB-CG2 4.03Å; N554-V557 WeakPolarHBondContact O-CG2 3.45Å; V557-L559 PolarHBondContact O-N 3.4Å; V557-F562 HydrophobicContact CG1-CB 3.77Å; V557-F562 HydrophobicContact CG1-CG 4.3Å
558D92.1Very high93.4Very high81 Ų8127.9 Ų27.943%0.43315%0.147SC..  trans-73.7110.3167.5-176.6-30.2000108.6D560 Q561 F562D558-D560 PolarHBondContact OD1-N 3.41Å; D558-Q561 HydrophobicContact CB-CB 3.99Å; D558-Q561 PolarHBondContact OD1-N 3Å; D558-Q561 VanDerWaalsContact OD1-N 3.1Å; D558-F562 VanDerWaalsContact O-CB 3.24Å; D558-F562 WeakPolarHBondContact O-CB 3.49Å; D558-F562 PolarHBondContact O-N 3.1Å
559L91.3Very high93.3Very high29 Ų2927.9 Ų27.915%0.15215%0.147CC..Hα-helixtrans-67.9-40.7-174.7-61.4-177.8000111.7C509 A510 M551 V557 Q561 F562 F563C509-L559 HydrophobicContact CB-CD1 4.02Å; C509-L559 HydrophobicContact CB-CD2 3.64Å; A510-L559 HydrophobicContact CB-CD1 4.23Å; M551-L559 HydrophobicContact CE-CD2 4.05Å; M551-L559 HydrophobicContact SD-CD2 3.77Å; V557-L559 PolarHBondContact O-N 3.4Å; L559-Q561 VanDerWaalsContact C-N 3.34Å; L559-Q561 PolarHBondContact O-N 3.35Å; L559-F562 PolarHBondContact O-N 2.7Å; L559-F563 HydrophobicContact CB-CD2 4.29Å; L559-F563 HydrophobicContact CB-CE2 4.38Å; L559-F563 HydrophobicContact CD2-CE2 4.41Å; L559-F563 WeakPolarHBondContact O-CD2 3.15Å; L559-F563 PolarHBondContact O-N 2.69Å
560D91.4Very high93.2Very high143 Ų14327.8 Ų27.877%0.76515%0.146SC*.Hα-helixtrans-64.9-44.6-177.2-66.5-27.8000110D558 S564D558-D560 PolarHBondContact OD1-N 3.41Å; D560-S564 PolarHBondContact O-N 2.63Å
561Q89.8Confident92.9Very high49 Ų4927.8 Ų27.823%0.22915%0.146CC..Hα-helixtrans-62.5-47.8173.8-174.5177.937.700111.6D558 L559 S564 L565D558-Q561 HydrophobicContact CB-CB 3.99Å; D558-Q561 PolarHBondContact OD1-N 3Å; D558-Q561 VanDerWaalsContact OD1-N 3.1Å; L559-Q561 VanDerWaalsContact C-N 3.34Å; L559-Q561 PolarHBondContact O-N 3.35Å; Q561-S564 PolarHBondContact O-N 3.21Å; Q561-S564 PolarHBondContact O-OG 3.49Å; Q561-L565 HydrophobicContact CG-CD1 4.49Å; Q561-L565 PolarHBondContact O-N 3.18Å
562F93Very high92.6Very high6 Ų627.9 Ų27.93%0.02615%0.147CC..Hα-helixtrans-60.2-49.8-178.7168-113.9000112.3W161 T547 V557 D558 L559 S564 L565 L566 I569W161-F562 HydrophobicContact CD2-CE2 4.07Å; W161-F562 AromaticContact CE2-CE2 3.68Å; W161-F562 AromaticContact CE3-CD2 3.98Å; W161-F562 HydrophobicContact CE3-CD2 3.98Å; W161-F562 AromaticContact CE3-CE2 3.96Å; W161-F562 HydrophobicContact CE3-CE2 3.96Å; W161-F562 HydrophobicContact CH2-CD1 4.23Å; W161-F562 AromaticContact CH2-CD2 3.11Å; W161-F562 HydrophobicContact CH2-CD2 3.11Å; W161-F562 HydrophobicContact CH2-CE1 4.2Å; W161-F562 AromaticContact CH2-CE2 3.07Å; W161-F562 HydrophobicContact CH2-CE2 3.07Å; W161-F562 AromaticContact CH2-CG 3.7Å; W161-F562 HydrophobicContact CH2-CG 3.7Å; W161-F562 AromaticContact CH2-CZ 3.63Å; W161-F562 HydrophobicContact CH2-CZ 3.63Å; W161-F562 AromaticContact CZ2-CD2 3.76Å; W161-F562 HydrophobicContact CZ2-CD2 3.76Å; W161-F562 HydrophobicContact CZ2-CE1 4.27Å; W161-F562 AromaticContact CZ2-CE2 3.16Å; W161-F562 HydrophobicContact CZ2-CE2 3.16Å; W161-F562 HydrophobicContact CZ2-CG 4.49Å; W161-F562 AromaticContact CZ2-CZ 3.43Å; W161-F562 HydrophobicContact CZ2-CZ 3.43Å; W161-F562 VanDerWaalsContact CZ2-CZ 3.43Å; W161-F562 AromaticContact CZ3-CD2 3.23Å; W161-F562 HydrophobicContact CZ3-CD2 3.23Å; W161-F562 AromaticContact CZ3-CE2 3.49Å; W161-F562 HydrophobicContact CZ3-CE2 3.49Å; W161-F562 VanDerWaalsContact CZ3-CE2 3.49Å; W161-F562 HydrophobicContact CZ3-CG 4.05Å; W161-F562 HydrophobicContact CZ3-CZ 4.46Å; T547-F562 HydrophobicContact CG2-CE1 3.84Å; T547-F562 HydrophobicContact CG2-CZ 4.35Å; V557-F562 HydrophobicContact CG1-CB 3.77Å; V557-F562 HydrophobicContact CG1-CG 4.3Å; D558-F562 VanDerWaalsContact O-CB 3.24Å; D558-F562 WeakPolarHBondContact O-CB 3.49Å; D558-F562 PolarHBondContact O-N 3.1Å; L559-F562 PolarHBondContact O-N 2.7Å; F562-S564 PolarHBondContact O-N 3.03Å; F562-L565 CarbonylContact O-C 3.53Å; F562-L565 WeakPolarHBondContact O-CA 3.34Å; F562-L565 PolarHBondContact O-N 2.95Å; F562-L566 HydrophobicContact CE1-CD1 4.28Å; F562-L566 HydrophobicContact CE2-CD1 4.09Å; F562-L566 HydrophobicContact CZ-CB 4.43Å; F562-L566 HydrophobicContact CZ-CD1 3.6Å; F562-L566 HydrophobicContact CZ-CG 4.47Å; F562-L566 PolarHBondContact O-N 2.94Å; F562-I569 HydrophobicContact CD2-CD1 3.72Å; F562-I569 HydrophobicContact CE2-CD1 3.89Å
563F93.5Very high92.3Very high36 Ų3628.1 Ų28.116%0.15815%0.148CC..Hα-helixtrans-65.8-26.7-179.4-79.3-72000112.7A502 L505 A506 T547 L559 L565 L566A502-F563 HydrophobicContact CB-CD1 4.41Å; L505-F563 HydrophobicContact CB-CE1 3.65Å; L505-F563 HydrophobicContact CB-CZ 3.86Å; A506-F563 HydrophobicContact CB-CD2 3.77Å; A506-F563 HydrophobicContact CB-CE1 4.41Å; A506-F563 HydrophobicContact CB-CE2 3.44Å; A506-F563 VanDerWaalsContact CB-CE2 3.44Å; A506-F563 HydrophobicContact CB-CG 4.45Å; A506-F563 HydrophobicContact CB-CZ 3.8Å; A506-F563 VanDerWaalsContact N-CZ 3.28Å; T547-F563 HydrophobicContact CG2-CZ 4.17Å; L559-F563 HydrophobicContact CB-CD2 4.29Å; L559-F563 HydrophobicContact CB-CE2 4.38Å; L559-F563 HydrophobicContact CD2-CE2 4.41Å; L559-F563 WeakPolarHBondContact O-CD2 3.15Å; L559-F563 PolarHBondContact O-N 2.69Å; F563-L565 PolarHBondContact O-N 2.76Å; F563-L566 HydrophobicContact CD1-CD2 3.73Å; F563-L566 HydrophobicContact CE1-CD2 3.84Å
564S91.4Very high91.9Very high54 Ų5428.6 Ų28.638%0.37815%0.15SC..Hα-helixtrans-67-25.217180.40000113.5D560 Q561 F562D560-S564 PolarHBondContact O-N 2.63Å; Q561-S564 PolarHBondContact O-N 3.21Å; Q561-S564 PolarHBondContact O-OG 3.49Å; F562-S564 PolarHBondContact O-N 3.03Å
565L92.3Very high91.4Very high4 Ų428.9 Ų28.92%0.02115%0.152CC..Hα-helixtrans-107.9-9.7-178.2-64.6178000113.7V149 L151 R158 M159 Q561 F562 F563 F568 I569V149-L565 HydrophobicContact CB-CD2 4.4Å; V149-L565 HydrophobicContact CG1-CD2 4.37Å; L151-L565 HydrophobicContact CD1-CD2 4.1Å; L151-L565 HydrophobicContact CD2-CD1 4.3Å; L151-L565 HydrophobicContact CD2-CD2 4.14Å; L151-L565 HydrophobicContact CG-CD2 4.16Å; R158-L565 HydrophobicContact CB-CD1 3.91Å; M159-L565 HydrophobicContact SD-CD1 4.48Å; M159-L565 HydrophobicContact SD-CD2 4.49Å; Q561-L565 HydrophobicContact CG-CD1 4.49Å; Q561-L565 PolarHBondContact O-N 3.18Å; F562-L565 CarbonylContact O-C 3.53Å; F562-L565 WeakPolarHBondContact O-CA 3.34Å; F562-L565 PolarHBondContact O-N 2.95Å; F563-L565 PolarHBondContact O-N 2.76Å; L565-F568 WeakPolarHBondContact O-CA 3.24Å; L565-F568 WeakPolarHBondContact O-CB 3.22Å; L565-F568 PolarHBondContact O-N 2.81Å; L565-I569 HydrophobicContact CB-CD1 3.8Å; L565-I569 HydrophobicContact CB-CG1 4.14Å; L565-I569 WeakPolarHBondContact O-CG1 3.49Å; L565-I569 PolarHBondContact O-N 3.05Å
566L94.6Very high91Very high1 Ų131.5 Ų31.51%0.00517%0.165CC..Hα-helixtrans-49-47.6-171.5168.263.9000113.8L505 L543 V546 F562 F563 F568 I569 A570L505-L566 HydrophobicContact CD1-CD2 4.46Å; L543-L566 HydrophobicContact CD2-CD1 3.74Å; L543-L566 HydrophobicContact CD2-CD2 4.15Å; L543-L566 HydrophobicContact CD2-CG 3.75Å; V546-L566 HydrophobicContact CG1-CD1 4.28Å; F562-L566 HydrophobicContact CE1-CD1 4.28Å; F562-L566 HydrophobicContact CE2-CD1 4.09Å; F562-L566 HydrophobicContact CZ-CB 4.43Å; F562-L566 HydrophobicContact CZ-CD1 3.6Å; F562-L566 HydrophobicContact CZ-CG 4.47Å; F562-L566 PolarHBondContact O-N 2.94Å; F563-L566 HydrophobicContact CD1-CD2 3.73Å; F563-L566 HydrophobicContact CE1-CD2 3.84Å; L566-F568 VanDerWaalsContact C-N 3.29Å; L566-F568 PolarHBondContact O-N 3.36Å; L566-I569 PolarHBondContact O-N 3.26Å; L566-A570 WeakPolarHBondContact O-CB 3.32Å; L566-A570 PolarHBondContact O-N 3.45Å
567P94.4Very high90.6Very high11 Ų1127.2 Ų27.27%0.07115%0.147CC..Hα-helixtrans-61.5-37.3178.9-23.734.8000113.3A571 F584 E585 L588P567-A571 WeakPolarHBondContact O-CB 3.5Å; P567-A571 PolarHBondContact O-N 3.22Å; P567-F584 HydrophobicContact CB-CB 3.93Å; P567-E585 HydrophobicContact CB-CG 3.66Å; P567-E585 HydrophobicContact CG-CG 3.92Å; P567-L588 HydrophobicContact CG-CD1 3.85Å
568F91.4Very high90.1Very high27 Ų2731.6 Ų31.612%0.11816%0.164CC..Hα-helixtrans-71.2-42.8177.3-57.7-79.1000111.1M159 L565 L566 A571 D572 R578 S581M159-F568 VanDerWaalsContact CE-C 3.49Å; M159-F568 HydrophobicContact CE-CB 3.64Å; M159-F568 HydrophobicContact SD-CB 4.19Å; L565-F568 WeakPolarHBondContact O-CA 3.24Å; L565-F568 WeakPolarHBondContact O-CB 3.22Å; L565-F568 PolarHBondContact O-N 2.81Å; L566-F568 VanDerWaalsContact C-N 3.29Å; L566-F568 PolarHBondContact O-N 3.36Å; F568-A571 PolarHBondContact O-N 2.78Å; F568-D572 VanDerWaalsContact O-CB 3.29Å; F568-D572 WeakPolarHBondContact O-CB 3.46Å; F568-D572 PolarHBondContact O-N 3.3Å; F568-R578 HydrophobicContact CB-CG 4.35Å; F568-R578 HydrophobicContact CD1-CG 3.92Å; F568-S581 VanDerWaalsContact CD1-CB 3.43Å; F568-S581 WeakPolarHBondContact CE1-OG 3.34Å
569I93.1Very high89.6Confident2 Ų232.5 Ų32.51%0.0117%0.165CC..Hα-helixtrans-60-49.6177.5-69.4171.7000109.5M159 W161 V546 F562 L565 L566 A571 D572 H573M159-I569 HydrophobicContact CE-CG1 3.95Å; M159-I569 HydrophobicContact SD-CG1 4.05Å; W161-I569 HydrophobicContact CB-CG2 3.6Å; W161-I569 HydrophobicContact CD2-CG2 3.89Å; W161-I569 HydrophobicContact CE3-CD1 4.1Å; W161-I569 HydrophobicContact CE3-CG2 4.42Å; W161-I569 HydrophobicContact CG-CG2 3.5Å; W161-I569 VanDerWaalsContact CG-CG2 3.5Å; V546-I569 HydrophobicContact CG1-CG2 4.01Å; F562-I569 HydrophobicContact CD2-CD1 3.72Å; F562-I569 HydrophobicContact CE2-CD1 3.89Å; L565-I569 HydrophobicContact CB-CD1 3.8Å; L565-I569 HydrophobicContact CB-CG1 4.14Å; L565-I569 WeakPolarHBondContact O-CG1 3.49Å; L565-I569 PolarHBondContact O-N 3.05Å; L566-I569 PolarHBondContact O-N 3.26Å; I569-A571 VanDerWaalsContact C-N 3.35Å; I569-A571 PolarHBondContact O-N 3.37Å; I569-D572 PolarHBondContact O-N 3.09Å; I569-H573 PolarHBondContact O-CD2 3.48Å; I569-H573 PolarHBondContact O-N 2.79Å
570A93.9Very high89.4Confident0 Ų031.3 Ų31.30%016%0.159CC..Hα-helixtrans-61.6-43.6178.200000111.9L543 V546 L566 D572 L574 F584L543-A570 HydrophobicContact CD2-CB 3.65Å; V546-A570 HydrophobicContact CG2-CB 4.46Å; L566-A570 WeakPolarHBondContact O-CB 3.32Å; L566-A570 PolarHBondContact O-N 3.45Å; A570-D572 PolarHBondContact O-N 3.18Å; A570-L574 HydrophobicContact CB-CD1 4.39Å; A570-L574 WeakPolarHBondContact O-CB 3.38Å; A570-L574 WeakPolarHBondContact O-CG 3.21Å; A570-L574 PolarHBondContact O-N 3.05Å; A570-F584 HydrophobicContact CB-CB 4.48Å; A570-F584 HydrophobicContact CB-CD1 3.65Å; A570-F584 HydrophobicContact CB-CD2 4.02Å; A570-F584 HydrophobicContact CB-CE1 3.77Å; A570-F584 HydrophobicContact CB-CE2 4.18Å; A570-F584 HydrophobicContact CB-CG 3.75Å; A570-F584 HydrophobicContact CB-CZ 4.03Å
571A90.6Very high89.4Confident0 Ų025.1 Ų25.10%013%0.126CC..Hα-helixtrans-59.1-48.6176.600000112.3P567 F568 I569 T575 N576 S577 M580 S581 F584P567-A571 WeakPolarHBondContact O-CB 3.5Å; P567-A571 PolarHBondContact O-N 3.22Å; F568-A571 PolarHBondContact O-N 2.78Å; I569-A571 VanDerWaalsContact C-N 3.35Å; I569-A571 PolarHBondContact O-N 3.37Å; A571-T575 WeakPolarHBondContact O-CA 3.45Å; A571-T575 WeakPolarHBondContact O-CB 3.49Å; A571-T575 PolarHBondContact O-N 2.95Å; A571-T575 PolarHBondContact O-OG1 3.29Å; A571-N576 PolarHBondContact O-N 3.43Å; A571-S577 CarbonylContact C-O 3.41Å; A571-S577 VanDerWaalsContact CB-O 3.27Å; A571-S577 WeakPolarHBondContact CB-O 3.19Å; A571-S577 VanDerWaalsContact O-O 3.07Å; A571-M580 VanDerWaalsContact CB-C 3.45Å; A571-M580 HydrophobicContact CB-CB 4.16Å; A571-S581 VanDerWaalsContact CB-N 3.29Å; A571-F584 HydrophobicContact CB-CD2 3.81Å; A571-F584 HydrophobicContact CB-CE2 3.94Å
572D87.3Confident89.5Confident6 Ų624.4 Ų24.43%0.03212%0.124CC..Hα-helixtrans-61.5-55.4-179-15866.2000110.9M159 R281 L282 F568 I569 A570 N576M159-D572 HydrophobicContact CE-CB 4.29Å; R281-D572 VanDerWaalsContact CZ-O 3.22Å; R281-D572 IonicContact CZ-OD1 2.67Å; R281-D572 IonicContact CZ-OD2 2.67Å; R281-D572 PolarHBondContact NH1-O 3.13Å; R281-D572 IonicContact NH1-OD1 3.23Å; R281-D572 PolarHBondContact NH1-OD1 2.85Å; R281-D572 IonicContact NH1-OD2 2.78Å; R281-D572 PolarHBondContact NH1-OD2 2.92Å; R281-D572 PolarHBondContact NH2-O 3.48Å; R281-D572 IonicContact NH2-OD1 3.98Å; R281-D572 PolarHBondContact NH2-OD1 2.92Å; R281-D572 IonicContact NH2-OD2 2.78Å; L282-D572 VanDerWaalsContact CD2-OD2 3.23Å; L282-D572 WeakPolarHBondContact CD2-OD2 3.36Å; F568-D572 VanDerWaalsContact O-CB 3.29Å; F568-D572 WeakPolarHBondContact O-CB 3.46Å; F568-D572 PolarHBondContact O-N 3.3Å; I569-D572 PolarHBondContact O-N 3.09Å; A570-D572 PolarHBondContact O-N 3.18Å; D572-N576 VanDerWaalsContact O-CA 3.24Å; D572-N576 WeakPolarHBondContact O-CA 3.36Å; D572-N576 PolarHBondContact O-N 3.13Å; D572-N576 VanDerWaalsContact O-N 3.09Å
573H90.1Very high89.6Confident6 Ų624.2 Ų24.23%0.02812%0.123CC..Hα-helixtrans-79.7-25.9-171.1-64.4-64.9000114.9M159 W161 Q278 H335 L336 I569M159-H573 PolarHBondContact O-NE2 3.42Å; W161-H573 WeakPolarHBondContact CB-NE2 3.4Å; Q278-H573 PolarHBondContact OE1-CE1 3.29Å; H335-H573 AromaticContact NE2-ND1 3.78Å; L336-H573 HydrophobicContact CD2-CB 4.04Å; I569-H573 PolarHBondContact O-CD2 3.48Å; I569-H573 PolarHBondContact O-N 2.79Å
574L89.3Confident89.7Confident9 Ų922.5 Ų22.55%0.04712%0.116CC..Hα-helixtrans-99.7-28.6-177.5-59.9176.4000113.7R332 L336 F542 V546 A570 F584R332-L574 HydrophobicContact CB-CD2 4.31Å; L336-L574 HydrophobicContact CD1-CD2 4.02Å; F542-L574 HydrophobicContact CB-CD1 3.44Å; F542-L574 VanDerWaalsContact CB-CD1 3.44Å; F542-L574 HydrophobicContact CD1-CD1 4.2Å; F542-L574 HydrophobicContact CD2-CD1 3.86Å; F542-L574 HydrophobicContact CG-CD1 3.58Å; V546-L574 HydrophobicContact CG2-CD1 3.64Å; V546-L574 HydrophobicContact CG2-CD2 4.26Å; V546-L574 HydrophobicContact CG2-CG 4Å; A570-L574 HydrophobicContact CB-CD1 4.39Å; A570-L574 WeakPolarHBondContact O-CB 3.38Å; A570-L574 WeakPolarHBondContact O-CG 3.21Å; A570-L574 PolarHBondContact O-N 3.05Å; L574-F584 HydrophobicContact CB-CZ 4.35Å; L574-F584 HydrophobicContact CD1-CE1 4.13Å; L574-F584 HydrophobicContact CD1-CZ 4.12Å
575T85.7Confident89.9Confident13 Ų1321.5 Ų21.58%0.0811%0.105CC..Hα-helixtrans-113.1-7.6-17679.90000113.6A571 S577 M580 F584 L671A571-T575 WeakPolarHBondContact O-CA 3.45Å; A571-T575 WeakPolarHBondContact O-CB 3.49Å; A571-T575 PolarHBondContact O-N 2.95Å; A571-T575 PolarHBondContact O-OG1 3.29Å; T575-S577 PolarHBondContact O-N 3.16Å; T575-S577 PolarHBondContact OG1-N 3.21Å; T575-S577 PolarHBondContact OG1-O 2.88Å; T575-M580 HydrophobicContact CG2-CB 4.38Å; T575-M580 WeakPolarHBondContact OG1-CB 3.46Å; T575-F584 HydrophobicContact CG2-CE2 3.8Å; T575-F584 HydrophobicContact CG2-CZ 3.98Å; T575-L671 HydrophobicContact CG2-CD1 3.74Å
576N82.6Confident90.1Very high73 Ų7321.3 Ų21.339%0.3910%0.104SC..SBendtrans59.415.7-170.8-62.7-61.2000114.4R281 A571 D572R281-N576 VanDerWaalsContact NH2-CA 3.26Å; R281-N576 PolarHBondContact NH2-O 3.48Å; A571-N576 PolarHBondContact O-N 3.43Å; D572-N576 VanDerWaalsContact O-CA 3.24Å; D572-N576 WeakPolarHBondContact O-CA 3.36Å; D572-N576 PolarHBondContact O-N 3.13Å; D572-N576 VanDerWaalsContact O-N 3.09Å
577S82.3Confident90.2Very high19 Ų1921.5 Ų21.513%0.13311%0.105CC..  trans-139.7122.7175.5175.70000109.9E287 A571 T575 M580E287-S577 PolarHBondContact OE1-OG 3.33Å; A571-S577 CarbonylContact C-O 3.41Å; A571-S577 VanDerWaalsContact CB-O 3.27Å; A571-S577 WeakPolarHBondContact CB-O 3.19Å; A571-S577 VanDerWaalsContact O-O 3.07Å; T575-S577 PolarHBondContact O-N 3.16Å; T575-S577 PolarHBondContact OG1-N 3.21Å; T575-S577 PolarHBondContact OG1-O 2.88Å; S577-M580 WeakPolarHBondContact O-CB 3.5Å; S577-M580 PolarHBondContact O-N 2.88Å
578R82.7Confident90.3Very high95 Ų9522.2 Ų22.236%0.35811%0.108SC..G310 helixtrans-75.4-23.3174170.1-166.767.2142.61.6113.2E287 F568 M580 S581E287-R578 VanDerWaalsContact CD-CB 3.41Å; E287-R578 HydrophobicContact CG-CB 4.15Å; E287-R578 VanDerWaalsContact OE1-C 3.31Å; E287-R578 VanDerWaalsContact OE1-CA 3.22Å; E287-R578 WeakPolarHBondContact OE1-CA 3.47Å; E287-R578 PolarHBondContact OE1-N 2.87Å; E287-R578 WeakPolarHBondContact OE2-CB 3.49Å; E287-R578 IonicContact OE2-CZ 3.48Å; E287-R578 IonicContact OE2-NE 3.77Å; E287-R578 PolarHBondContact OE2-NE 2.79Å; E287-R578 IonicContact OE2-NH2 3.68Å; E287-R578 PolarHBondContact OE2-NH2 3.35Å; F568-R578 HydrophobicContact CB-CG 4.35Å; F568-R578 HydrophobicContact CD1-CG 3.92Å; R578-M580 PolarHBondContact O-N 3.38Å; R578-M580 VanDerWaalsContact O-N 3.13Å; R578-S581 WeakPolarHBondContact O-CB 3.49Å; R578-S581 PolarHBondContact O-N 3.14Å
579Q81.3Confident90.5Very high100 Ų10023.2 Ų23.247%0.46712%0.115SC..G310 helixtrans-58.4-23.5169.2-71.4177.73.900111.7E287 S581E287-Q579 WeakPolarHBondContact OE1-CG 3.35Å; E287-Q579 PolarHBondContact OE1-N 3Å; E287-Q579 PolarHBondContact OE2-N 3.38Å; Q579-S581 PolarHBondContact O-N 2.94Å
580M87.1Confident90.7Very high4 Ų423.1 Ų23.12%0.0211%0.114CC..G310 helixtrans-76.38173.1-68-56.6-61.100114.4A571 T575 S577 R578 I582 L583 F584 M665 L671 V675A571-M580 VanDerWaalsContact CB-C 3.45Å; A571-M580 HydrophobicContact CB-CB 4.16Å; T575-M580 HydrophobicContact CG2-CB 4.38Å; T575-M580 WeakPolarHBondContact OG1-CB 3.46Å; S577-M580 WeakPolarHBondContact O-CB 3.5Å; S577-M580 PolarHBondContact O-N 2.88Å; R578-M580 PolarHBondContact O-N 3.38Å; R578-M580 VanDerWaalsContact O-N 3.13Å; M580-I582 PolarHBondContact O-N 3.5Å; M580-I582 VanDerWaalsContact O-N 3.15Å; M580-L583 HydrophobicContact CE-CB 3.79Å; M580-L583 HydrophobicContact CE-CD2 4.06Å; M580-L583 HydrophobicContact CE-CG 4.48Å; M580-L583 VanDerWaalsContact O-CB 3.31Å; M580-L583 WeakPolarHBondContact O-CB 3.28Å; M580-L583 PolarHBondContact O-N 2.98Å; M580-F584 WeakPolarHBondContact O-CD2 3.36Å; M580-M665 HydrophobicContact CE-CE 3.17Å; M580-M665 HydrophobicContact CE-SD 3.66Å; M580-M665 HydrophobicContact SD-CE 3.16Å; M580-M665 WeakPolarHBondContact SD-CE 3.36Å; M580-M665 HydrophobicContact SD-CG 3.86Å; M580-M665 HydrophobicContact SD-SD 3.37Å; M580-L671 HydrophobicContact CE-CD1 3.44Å; M580-L671 VanDerWaalsContact CE-CD1 3.44Å; M580-L671 HydrophobicContact CE-CD2 4.17Å; M580-L671 HydrophobicContact CE-CG 3.95Å; M580-L671 HydrophobicContact CG-CD1 3.95Å; M580-L671 HydrophobicContact CG-CD2 3.68Å; M580-L671 HydrophobicContact CG-CG 4.35Å; M580-L671 HydrophobicContact SD-CD1 4.19Å; M580-L671 HydrophobicContact SD-CD2 3.86Å; M580-L671 HydrophobicContact SD-CG 4.31Å; M580-V675 HydrophobicContact CE-CG2 3.75Å
581S90.7Very high90.7Very high12 Ų1223.1 Ų23.18%0.08411%0.114CC..Hα-helixtrans-53.2-34.1169.9740000111.3F568 A571 R578 Q579 L583 F584 E585F568-S581 VanDerWaalsContact CD1-CB 3.43Å; F568-S581 WeakPolarHBondContact CE1-OG 3.34Å; A571-S581 VanDerWaalsContact CB-N 3.29Å; R578-S581 WeakPolarHBondContact O-CB 3.49Å; R578-S581 PolarHBondContact O-N 3.14Å; Q579-S581 PolarHBondContact O-N 2.94Å; S581-L583 PolarHBondContact O-N 2.86Å; S581-L583 VanDerWaalsContact O-N 3.16Å; S581-F584 PolarHBondContact O-N 3.44Å; S581-E585 WeakPolarHBondContact CB-OE1 3.31Å; S581-E585 WeakPolarHBondContact O-CG 3.37Å; S581-E585 PolarHBondContact O-N 3.25Å; S581-E585 PolarHBondContact OG-OE1 2.93Å
582I92.7Very high91Very high35 Ų3525.7 Ų25.718%0.17914%0.136CC..Hα-helixtrans-52.4-35.4174.9-167.272.7000113.2M580 T586 R657 A661M580-I582 PolarHBondContact O-N 3.5Å; M580-I582 VanDerWaalsContact O-N 3.15Å; I582-T586 VanDerWaalsContact O-CB 3.22Å; I582-T586 WeakPolarHBondContact O-CB 3.3Å; I582-T586 PolarHBondContact O-N 3.12Å; I582-T586 PolarHBondContact O-OG1 2.9Å; I582-R657 HydrophobicContact CD1-CB 4.2Å; I582-R657 HydrophobicContact CG1-CB 4.47Å; I582-A661 HydrophobicContact CB-CB 4.45Å; I582-A661 HydrophobicContact CG1-CB 4.23Å; I582-A661 HydrophobicContact CG2-CB 3.45Å; I582-A661 VanDerWaalsContact CG2-CB 3.45Å
583L94.3Very high91.4Very high1 Ų126.5 Ų26.51%0.00514%0.14CC..Hα-helixtrans-63.1-49.1176.2178.161.7000110.5M580 S581 T586 I587 L658 C674 V675 V678M580-L583 HydrophobicContact CE-CB 3.79Å; M580-L583 HydrophobicContact CE-CD2 4.06Å; M580-L583 HydrophobicContact CE-CG 4.48Å; M580-L583 VanDerWaalsContact O-CB 3.31Å; M580-L583 WeakPolarHBondContact O-CB 3.28Å; M580-L583 PolarHBondContact O-N 2.98Å; S581-L583 PolarHBondContact O-N 2.86Å; S581-L583 VanDerWaalsContact O-N 3.16Å; L583-T586 WeakPolarHBondContact O-CB 3.47Å; L583-T586 PolarHBondContact O-N 3Å; L583-I587 HydrophobicContact CG-CD1 4.39Å; L583-I587 WeakPolarHBondContact O-CG1 3.31Å; L583-I587 PolarHBondContact O-N 3.37Å; L583-L658 HydrophobicContact CB-CD2 4.43Å; L583-L658 HydrophobicContact CD1-CD2 3.86Å; L583-C674 HydrophobicContact CD2-CB 4.29Å; L583-V675 HydrophobicContact CD1-CG2 4.28Å; L583-V678 HydrophobicContact CD1-CB 4.07Å; L583-V678 HydrophobicContact CD1-CG1 4.31Å; L583-V678 HydrophobicContact CD1-CG2 3.86Å
584F95.6Very high91.6Very high0 Ų026.2 Ų26.20%014%0.138CC..Hα-helixtrans-75.6-36.8-176.1-64-74.7000112.7F542 L543 P567 A570 A571 L574 T575 M580 S581 T586 I587 L588F542-F584 HydrophobicContact CB-CE1 3.99Å; F542-F584 HydrophobicContact CD2-CE1 4.06Å; F542-F584 HydrophobicContact CD2-CZ 4.27Å; L543-F584 HydrophobicContact CD1-CB 4.4Å; L543-F584 HydrophobicContact CD1-CD1 4.27Å; L543-F584 HydrophobicContact CD2-CB 4.11Å; L543-F584 HydrophobicContact CD2-CD1 3.74Å; L543-F584 HydrophobicContact CD2-CG 4.24Å; L543-F584 HydrophobicContact CG-CD1 3.78Å; P567-F584 HydrophobicContact CB-CB 3.93Å; A570-F584 HydrophobicContact CB-CB 4.48Å; A570-F584 HydrophobicContact CB-CD1 3.65Å; A570-F584 HydrophobicContact CB-CD2 4.02Å; A570-F584 HydrophobicContact CB-CE1 3.77Å; A570-F584 HydrophobicContact CB-CE2 4.18Å; A570-F584 HydrophobicContact CB-CG 3.75Å; A570-F584 HydrophobicContact CB-CZ 4.03Å; A571-F584 HydrophobicContact CB-CD2 3.81Å; A571-F584 HydrophobicContact CB-CE2 3.94Å; L574-F584 HydrophobicContact CB-CZ 4.35Å; L574-F584 HydrophobicContact CD1-CE1 4.13Å; L574-F584 HydrophobicContact CD1-CZ 4.12Å; T575-F584 HydrophobicContact CG2-CE2 3.8Å; T575-F584 HydrophobicContact CG2-CZ 3.98Å; M580-F584 WeakPolarHBondContact O-CD2 3.36Å; S581-F584 PolarHBondContact O-N 3.44Å; F584-T586 VanDerWaalsContact C-N 3.25Å; F584-T586 PolarHBondContact O-N 3.2Å; F584-I587 HydrophobicContact CD1-CD1 4.22Å; F584-I587 PolarHBondContact O-N 3Å; F584-L588 WeakPolarHBondContact O-CG 3.27Å; F584-L588 PolarHBondContact O-N 3.23Å
585E95.7Very high91.7Very high33 Ų3328.4 Ų28.415%0.15415%0.146CC..Hα-helixtrans-58.7-41.2168.4-71.2169.3-145.900110.7P567 S581 L588 N589P567-E585 HydrophobicContact CB-CG 3.66Å; P567-E585 HydrophobicContact CG-CG 3.92Å; S581-E585 WeakPolarHBondContact CB-OE1 3.31Å; S581-E585 WeakPolarHBondContact O-CG 3.37Å; S581-E585 PolarHBondContact O-N 3.25Å; S581-E585 PolarHBondContact OG-OE1 2.93Å; E585-L588 PolarHBondContact O-N 2.98Å; E585-N589 WeakPolarHBondContact O-CB 3.34Å; E585-N589 VanDerWaalsContact O-CG 3.24Å; E585-N589 PolarHBondContact O-N 3.44Å; E585-N589 PolarHBondContact O-ND2 3.42Å
586T96.5Very high92Very high1 Ų129.3 Ų29.31%0.00616%0.158CC..Hα-helixtrans-65.7-41.7176.9-60.30000111.7I582 L583 F584 L588 N589 M590 C654 L658 I682I582-T586 VanDerWaalsContact O-CB 3.22Å; I582-T586 WeakPolarHBondContact O-CB 3.3Å; I582-T586 PolarHBondContact O-N 3.12Å; I582-T586 PolarHBondContact O-OG1 2.9Å; L583-T586 WeakPolarHBondContact O-CB 3.47Å; L583-T586 PolarHBondContact O-N 3Å; F584-T586 VanDerWaalsContact C-N 3.25Å; F584-T586 PolarHBondContact O-N 3.2Å; T586-L588 VanDerWaalsContact C-N 3.35Å; T586-L588 PolarHBondContact O-N 3.31Å; T586-N589 PolarHBondContact O-N 2.97Å; T586-M590 VanDerWaalsContact O-CB 3.27Å; T586-M590 WeakPolarHBondContact O-CB 3.33Å; T586-M590 PolarHBondContact O-N 2.95Å; T586-C654 HydrophobicContact CG2-CB 3.65Å; T586-L658 HydrophobicContact CG2-CD1 3.74Å; T586-L658 HydrophobicContact CG2-CD2 4.35Å; T586-L658 HydrophobicContact CG2-CG 3.91Å; T586-I682 HydrophobicContact CG2-CD1 3.76Å
587I96.6Very high92.4Very high4 Ų426.2 Ų26.22%0.02114%0.141CC..Hα-helixtrans-59.7-45.3174.5-67.4166.3000110.8C499 L540 L543 L583 F584 M590 A591 V678C499-I587 HydrophobicContact CB-CG2 4.43Å; L540-I587 HydrophobicContact CD2-CB 4.47Å; L540-I587 HydrophobicContact CD2-CD1 4Å; L540-I587 HydrophobicContact CD2-CG1 3.79Å; L540-I587 HydrophobicContact CD2-CG2 3.91Å; L543-I587 HydrophobicContact CD1-CB 4.12Å; L543-I587 HydrophobicContact CD1-CG2 3.83Å; L583-I587 HydrophobicContact CG-CD1 4.39Å; L583-I587 WeakPolarHBondContact O-CG1 3.31Å; L583-I587 PolarHBondContact O-N 3.37Å; F584-I587 HydrophobicContact CD1-CD1 4.22Å; F584-I587 PolarHBondContact O-N 3Å; I587-M590 WeakPolarHBondContact O-CB 3.46Å; I587-M590 PolarHBondContact O-N 3.02Å; I587-A591 PolarHBondContact O-N 3.26Å; I587-V678 HydrophobicContact CD1-CG2 4.01Å; I587-V678 HydrophobicContact CG1-CG1 4.11Å; I587-V678 HydrophobicContact CG1-CG2 4.05Å
588L96.7Very high92.7Very high27 Ų2725.8 Ų25.814%0.14114%0.138CC..Hα-helixtrans-63.9-41.8177.8-70.3178000112.5A502 L543 P567 F584 E585 T586 A591 A592A502-L588 HydrophobicContact CB-CD2 4.05Å; L543-L588 HydrophobicContact CD1-CD2 3.77Å; L543-L588 HydrophobicContact CD1-CG 3.81Å; P567-L588 HydrophobicContact CG-CD1 3.85Å; F584-L588 WeakPolarHBondContact O-CG 3.27Å; F584-L588 PolarHBondContact O-N 3.23Å; E585-L588 PolarHBondContact O-N 2.98Å; T586-L588 VanDerWaalsContact C-N 3.35Å; T586-L588 PolarHBondContact O-N 3.31Å; L588-A591 PolarHBondContact O-N 3.29Å; L588-A592 PolarHBondContact O-N 3.48Å
589N96.4Very high92.9Very high48 Ų4826 Ų2626%0.25715%0.146SC..Hα-helixtrans-64.2-42.3175.6-71.6-37000111.3E585 T586 A591 A592 I593E585-N589 WeakPolarHBondContact O-CB 3.34Å; E585-N589 VanDerWaalsContact O-CG 3.24Å; E585-N589 PolarHBondContact O-N 3.44Å; E585-N589 PolarHBondContact O-ND2 3.42Å; T586-N589 PolarHBondContact O-N 2.97Å; N589-A591 PolarHBondContact O-N 3.25Å; N589-A592 PolarHBondContact O-N 3.45Å; N589-I593 WeakPolarHBondContact O-CD1 3.37Å; N589-I593 WeakPolarHBondContact O-CG1 3.42Å; N589-I593 PolarHBondContact O-N 2.98Å
590M95.8Very high93Very high0 Ų023.5 Ų23.50%014%0.137CC..Hα-helixtrans-58.8-46.1175.6-176.8177.975.300111.5C499 L540 T586 I587 A592 I593 E594 L651 V681 I682 M685C499-M590 HydrophobicContact CB-CE 4.26Å; C499-M590 VanDerWaalsContact SG-CE 3.52Å; L540-M590 HydrophobicContact CD1-CE 3.88Å; L540-M590 HydrophobicContact CD2-CE 3.67Å; L540-M590 HydrophobicContact CG-CE 4.47Å; T586-M590 VanDerWaalsContact O-CB 3.27Å; T586-M590 WeakPolarHBondContact O-CB 3.33Å; T586-M590 PolarHBondContact O-N 2.95Å; I587-M590 WeakPolarHBondContact O-CB 3.46Å; I587-M590 PolarHBondContact O-N 3.02Å; M590-A592 PolarHBondContact O-N 3.13Å; M590-I593 PolarHBondContact O-N 2.92Å; M590-E594 PolarHBondContact O-N 2.85Å; M590-L651 HydrophobicContact CG-CD2 4.28Å; M590-V681 HydrophobicContact CE-CG1 3.94Å; M590-V681 HydrophobicContact SD-CB 4.27Å; M590-V681 HydrophobicContact SD-CG1 3.77Å; M590-I682 HydrophobicContact SD-CG1 3.63Å; M590-M685 HydrophobicContact CG-CE 3.91Å; M590-M685 HydrophobicContact CG-SD 3.39Å; M590-M685 WeakPolarHBondContact CG-SD 3.39Å; M590-M685 HydrophobicContact SD-SD 3.75Å
591A95.5Very high92.6Very high0 Ų023.7 Ų23.70%014%0.139CC..Hα-helixtrans-61.3-4317600000112.2C499 E500 T501 I587 L588 N589 I593 E594 R595C499-A591 HydrophobicContact CB-CB 4.15Å; C499-A591 WeakPolarHBondContact SG-CA 3.46Å; C499-A591 WeakPolarHBondContact SG-CB 3.32Å; E500-A591 VanDerWaalsContact O-CB 3.27Å; E500-A591 WeakPolarHBondContact O-CB 3.43Å; T501-A591 HydrophobicContact CG2-CB 3.86Å; T501-A591 WeakPolarHBondContact CG2-O 3.42Å; I587-A591 PolarHBondContact O-N 3.26Å; L588-A591 PolarHBondContact O-N 3.29Å; N589-A591 PolarHBondContact O-N 3.25Å; A591-I593 VanDerWaalsContact C-N 3.32Å; A591-I593 PolarHBondContact O-N 3.43Å; A591-E594 PolarHBondContact O-N 3Å; A591-R595 WeakPolarHBondContact O-CB 3.37Å; A591-R595 PolarHBondContact O-N 3.24Å
592A95.6Very high91.4Very high54 Ų5424.8 Ų24.845%0.44615%0.151SC..Hα-helixtrans-63.3-38177.300000112.1L588 N589 M590 G596L588-A592 PolarHBondContact O-N 3.48Å; N589-A592 PolarHBondContact O-N 3.45Å; M590-A592 PolarHBondContact O-N 3.13Å; A592-G596 WeakPolarHBondContact O-CA 3.4Å; A592-G596 PolarHBondContact O-N 2.86Å
593I96.3Very high89.6Confident22 Ų2229.9 Ų29.911%0.11318%0.179CC..Hα-helixtrans-66.5-46.7175.2-64.3158.5000110.9N589 M590 A591 G596 L597 A647 E650 L651N589-I593 WeakPolarHBondContact O-CD1 3.37Å; N589-I593 WeakPolarHBondContact O-CG1 3.42Å; N589-I593 PolarHBondContact O-N 2.98Å; M590-I593 PolarHBondContact O-N 2.92Å; A591-I593 VanDerWaalsContact C-N 3.32Å; A591-I593 PolarHBondContact O-N 3.43Å; I593-G596 PolarHBondContact O-N 2.85Å; I593-L597 WeakPolarHBondContact O-CB 3.28Å; I593-L597 PolarHBondContact O-N 2.88Å; I593-A647 HydrophobicContact CG2-CB 3.74Å; I593-E650 HydrophobicContact CD1-CB 3.84Å; I593-E650 HydrophobicContact CD1-CG 3.65Å; I593-E650 HydrophobicContact CG1-CB 4.35Å; I593-E650 HydrophobicContact CG1-CG 4.16Å; I593-L651 HydrophobicContact CD1-CD2 3.99Å; I593-L651 HydrophobicContact CD1-CG 4.12Å; I593-L651 HydrophobicContact CG2-CD1 4.36Å; I593-L651 HydrophobicContact CG2-CD2 4.41Å; I593-L651 HydrophobicContact CG2-CG 4.13Å
594E94.2Very high87.8Confident0 Ų033.2 Ų33.20%019%0.191CC..Hα-helixtrans-57.3-51177.2177172.1-151.400111.8Y497 F498 C499 M590 A591 S598 S609 F611 M685Y497-E594 WeakPolarHBondContact CA-OE1 3.24Å; Y497-E594 HydrophobicContact CD1-CG 3.78Å; Y497-E594 HydrophobicContact CE1-CG 4.24Å; F498-E594 PolarHBondContact N-OE1 3.32Å; F498-E594 VanDerWaalsContact N-OE1 3.08Å; F498-E594 PolarHBondContact N-OE2 3.16Å; F498-E594 VanDerWaalsContact N-OE2 3.07Å; C499-E594 PolarHBondContact N-OE2 3.05Å; M590-E594 PolarHBondContact O-N 2.85Å; A591-E594 PolarHBondContact O-N 3Å; E594-S598 WeakPolarHBondContact O-CB 3.47Å; E594-S598 PolarHBondContact O-N 2.94Å; E594-S598 PolarHBondContact O-OG 3.22Å; E594-S609 WeakPolarHBondContact OE1-CB 3.3Å; E594-S609 PolarHBondContact OE1-OG 3Å; E594-F611 HydrophobicContact CB-CD2 4.21Å; E594-F611 HydrophobicContact CB-CE2 4.45Å; E594-F611 HydrophobicContact CG-CD2 4.08Å; E594-M685 HydrophobicContact CB-CE 3.82Å
595R91.9Very high85.8Confident56 Ų5636.1 Ų36.121%0.21122%0.222CC..Hα-helixtrans-64-48.1178.3-177.5-180179.179.7-9111.6T501 I504 A591 L597 S598 L599T501-R595 HydrophobicContact CG2-CB 3.89Å; T501-R595 HydrophobicContact CG2-CG 4.38Å; I504-R595 VanDerWaalsContact CD1-CZ 3.48Å; A591-R595 WeakPolarHBondContact O-CB 3.37Å; A591-R595 PolarHBondContact O-N 3.24Å; R595-L597 PolarHBondContact O-N 3.19Å; R595-S598 PolarHBondContact O-N 3.19Å; R595-L599 HydrophobicContact CG-CD1 3.88Å; R595-L599 HydrophobicContact CG-CG 4.32Å; R595-L599 WeakPolarHBondContact O-CB 3.33Å; R595-L599 WeakPolarHBondContact O-CG 3.46Å; R595-L599 PolarHBondContact O-N 3.07Å
596G90.9Very high84.2Confident32 Ų3236.8 Ų36.833%0.3323%0.23SC..Hα-helixtrans-58.2-47.3-179.700000111.9A592 I593 L599 T600A592-G596 WeakPolarHBondContact O-CA 3.4Å; A592-G596 PolarHBondContact O-N 2.86Å; I593-G596 PolarHBondContact O-N 2.85Å; G596-L599 PolarHBondContact O-N 2.68Å; G596-T600 VanDerWaalsContact O-CG2 3.25Å; G596-T600 WeakPolarHBondContact O-CG2 3.46Å; G596-T600 PolarHBondContact O-N 2.85Å; G596-T600 PolarHBondContact O-OG1 3.23Å
597L91.1Very high83.1Confident7 Ų742 Ų424%0.03726%0.262CS..Hα-helixtrans-61.9-47.7176.8-177.363.8000111.3I593 R595 L599 T600 M601 V610 F611 F644 A647I593-L597 WeakPolarHBondContact O-CB 3.28Å; I593-L597 PolarHBondContact O-N 2.88Å; R595-L597 PolarHBondContact O-N 3.19Å; L597-L599 PolarHBondContact O-N 2.82Å; L597-T600 WeakPolarHBondContact CA-OG1 3.15Å; L597-T600 PolarHBondContact O-N 2.82Å; L597-T600 VanDerWaalsContact O-N 3.16Å; L597-T600 PolarHBondContact O-OG1 2.85Å; L597-M601 HydrophobicContact CD1-CG 4.39Å; L597-M601 WeakPolarHBondContact O-CG 3.48Å; L597-M601 PolarHBondContact O-N 2.85Å; L597-M601 VanDerWaalsContact O-N 3.09Å; L597-V610 HydrophobicContact CD2-CG1 4.2Å; L597-V610 HydrophobicContact CG-CG1 4.42Å; L597-F611 HydrophobicContact CB-CE2 4.39Å; L597-F611 HydrophobicContact CD2-CD2 4.25Å; L597-F611 HydrophobicContact CD2-CE1 4Å; L597-F611 HydrophobicContact CD2-CE2 3.52Å; L597-F611 HydrophobicContact CD2-CZ 3.38Å; L597-F644 HydrophobicContact CD1-CD1 4.18Å; L597-F644 HydrophobicContact CD1-CE1 4.37Å; L597-F644 HydrophobicContact CD1-CG 4.49Å; L597-F644 HydrophobicContact CD2-CD1 3.79Å; L597-F644 HydrophobicContact CD2-CE1 3.72Å; L597-F644 HydrophobicContact CG-CE1 4.46Å; L597-A647 HydrophobicContact CD2-CB 4.3Å
598S89.4Confident82.6Confident10 Ų1044.1 Ų44.17%0.0727%0.274CS..Hα-helixtrans-61.3-43.3-178.7-560000112.2E594 R595 T600 M601 G602 V610E594-S598 WeakPolarHBondContact O-CB 3.47Å; E594-S598 PolarHBondContact O-N 2.94Å; E594-S598 PolarHBondContact O-OG 3.22Å; R595-S598 PolarHBondContact O-N 3.19Å; S598-T600 PolarHBondContact O-N 2.87Å; S598-M601 PolarHBondContact O-N 3.31Å; S598-G602 PolarHBondContact O-N 3.01Å; S598-V610 PolarHBondContact OG-N 3.07Å; S598-V610 VanDerWaalsContact OG-N 3.13Å
599L85.7Confident82.3Confident100 Ų10042.8 Ų42.852%0.52427%0.268SS..Hα-helixtrans-63.5-38.9174.9-70.5174.5000112.6R595 G596 L597 M601 G602R595-L599 HydrophobicContact CG-CD1 3.88Å; R595-L599 HydrophobicContact CG-CG 4.32Å; R595-L599 WeakPolarHBondContact O-CB 3.33Å; R595-L599 WeakPolarHBondContact O-CG 3.46Å; R595-L599 PolarHBondContact O-N 3.07Å; G596-L599 PolarHBondContact O-N 2.68Å; L597-L599 PolarHBondContact O-N 2.82Å; L599-M601 VanDerWaalsContact C-N 3.33Å; L599-M601 PolarHBondContact O-N 2.78Å; L599-G602 PolarHBondContact O-N 2.75Å
600T83.9Confident81.9Confident47 Ų4741 Ų4129%0.28826%0.258SS..Hα-helixtrans-70.7-26.6179.658.80000114.1G596 L597 S598 G602 Y643G596-T600 VanDerWaalsContact O-CG2 3.25Å; G596-T600 WeakPolarHBondContact O-CG2 3.46Å; G596-T600 PolarHBondContact O-N 2.85Å; G596-T600 PolarHBondContact O-OG1 3.23Å; L597-T600 WeakPolarHBondContact CA-OG1 3.15Å; L597-T600 PolarHBondContact O-N 2.82Å; L597-T600 VanDerWaalsContact O-N 3.16Å; L597-T600 PolarHBondContact O-OG1 2.85Å; S598-T600 PolarHBondContact O-N 2.87Å; T600-G602 VanDerWaalsContact C-N 3.32Å; T600-Y643 HydrophobicContact CG2-CD1 4.4Å; T600-Y643 HydrophobicContact CG2-CD2 4.39Å; T600-Y643 HydrophobicContact CG2-CE1 4.16Å; T600-Y643 HydrophobicContact CG2-CE2 4.13Å
601M79Confident81.8Confident9 Ų941 Ų414%0.04426%0.258CS..Hα-helixtrans-78.2-21.8174.7-64.2-65.4-70.800111.8L597 S598 L599 R604 V610 L623 H640 F644L597-M601 HydrophobicContact CD1-CG 4.39Å; L597-M601 WeakPolarHBondContact O-CG 3.48Å; L597-M601 PolarHBondContact O-N 2.85Å; L597-M601 VanDerWaalsContact O-N 3.09Å; S598-M601 PolarHBondContact O-N 3.31Å; L599-M601 VanDerWaalsContact C-N 3.33Å; L599-M601 PolarHBondContact O-N 2.78Å; M601-R604 PolarHBondContact O-NH2 2.81Å; M601-V610 HydrophobicContact CB-CG2 3.83Å; M601-V610 HydrophobicContact CG-CG1 4.47Å; M601-V610 HydrophobicContact CG-CG2 3.82Å; M601-L623 HydrophobicContact CE-CD2 3.95Å; M601-H640 HydrophobicContact CE-CB 4.19Å; M601-H640 HydrophobicContact SD-CB 3.78Å; M601-H640 PolarHBondContact SD-CD2 2.93Å; M601-F644 HydrophobicContact CE-CE2 3.89Å; M601-F644 HydrophobicContact CE-CZ 4.15Å; M601-F644 HydrophobicContact SD-CE2 4.14Å; M601-F644 HydrophobicContact SD-CZ 4.49Å
602G65.8Low81.6Confident34 Ų3441.1 Ų41.135%0.35126%0.259SS..  trans105.8139.6173.100000112.9S598 L599 T600 R604S598-G602 PolarHBondContact O-N 3.01Å; L599-G602 PolarHBondContact O-N 2.75Å; T600-G602 VanDerWaalsContact C-N 3.32Å; G602-R604 VanDerWaalsContact C-N 3.31Å; G602-R604 PolarHBondContact O-N 3.03Å
603D54.5Low81.3Confident142 Ų14240.2 Ų40.276%0.75925%0.246SC*.  trans-77.579.5172.1-167.26.7000109.5G605D603-G605 VanDerWaalsContact C-N 3.27Å; D603-G605 PolarHBondContact O-N 3.29Å
604R56.9Low80.9Confident71 Ų7139.1 Ų39.127%0.26824%0.24SC..SBendtrans-9325-174.9-60-172.7-16715611.4113.1M601 G602 S606 E622 G624 N625M601-R604 PolarHBondContact O-NH2 2.81Å; G602-R604 VanDerWaalsContact C-N 3.31Å; G602-R604 PolarHBondContact O-N 3.03Å; R604-S606 VanDerWaalsContact C-N 3.31Å; R604-E622 WeakPolarHBondContact CD-OE2 3.47Å; R604-E622 PolarHBondContact NH1-O 3.5Å; R604-E622 IonicContact NH1-OE2 3.84Å; R604-G624 VanDerWaalsContact NH1-CA 3.26Å; R604-G624 VanDerWaalsContact NH1-N 3.18Å; R604-G624 PolarHBondContact NH1-O 2.83Å; R604-N625 WeakPolarHBondContact CD-OD1 3.33Å; R604-N625 PolarHBondContact NE-OD1 2.87Å
605G53.1Low80.7Confident62 Ų6239.3 Ų39.364%0.63924%0.241SC*.SBendtrans83.25-171.600000114D603 V607D603-G605 VanDerWaalsContact C-N 3.27Å; D603-G605 PolarHBondContact O-N 3.29Å; G605-V607 PolarHBondContact O-N 3.42Å
606S61.6Low80.6Confident46 Ų4640.8 Ų40.832%0.32225%0.253SS..  trans-69.1115.5167.7-179.30000109.2R604 V608R604-S606 VanDerWaalsContact C-N 3.31Å; S606-V608 PolarHBondContact O-N 2.93Å; S606-V608 PolarHBondContact OG-N 3.33Å; S606-V608 PolarHBondContact OG-O 3.42Å
607V74.1Confident80.4Confident112 Ų11242.2 Ų42.268%0.67925%0.253SS*.  trans-72.1-14.5176.1-170.30000111.3P495 G605P495-V607 VanDerWaalsContact O-O 3.1Å; G605-V607 PolarHBondContact O-N 3.42Å
608V85.7Confident80.2Confident47 Ų4741.9 Ų41.929%0.28525%0.251SS..SBendtrans-113.3154.5-174.3-56.10000112.8S606 V612 Q613S606-V608 PolarHBondContact O-N 2.93Å; S606-V608 PolarHBondContact OG-N 3.33Å; S606-V608 PolarHBondContact OG-O 3.42Å; V608-V612 HydrophobicContact CB-CB 4.28Å; V608-V612 HydrophobicContact CB-CG1 4Å; V608-V612 HydrophobicContact CG1-CG1 4.31Å; V608-V612 HydrophobicContact CG2-CG1 4.46Å; V608-Q613 HydrophobicContact CG2-CB 4.08Å
609S89.8Confident79.8Confident0 Ų044.4 Ų44.40%026%0.264CS..  trans-64153.5174.888.80000111.2G496 E594 F611 V612 Q613G496-S609 WeakPolarHBondContact O-CB 3.38Å; G496-S609 PolarHBondContact O-N 2.85Å; G496-S609 PolarHBondContact O-OG 3.47Å; E594-S609 WeakPolarHBondContact OE1-CB 3.3Å; E594-S609 PolarHBondContact OE1-OG 3Å; S609-F611 PolarHBondContact O-N 3.22Å; S609-F611 PolarHBondContact OG-N 3.38Å; S609-V612 PolarHBondContact O-N 3.47Å; S609-V612 WeakPolarHBondContact OG-CG2 3.4Å; S609-V612 PolarHBondContact OG-N 2.89Å; S609-Q613 PolarHBondContact O-N 3.15Å
610V90.1Very high79.5Confident9 Ų943.1 Ų43.16%0.05526%0.262CS..Hα-helixtrans-58.9-34.1178.71680000111.3L597 S598 M601 I614 L621 F644L597-V610 HydrophobicContact CD2-CG1 4.2Å; L597-V610 HydrophobicContact CG-CG1 4.42Å; S598-V610 PolarHBondContact OG-N 3.07Å; S598-V610 VanDerWaalsContact OG-N 3.13Å; M601-V610 HydrophobicContact CB-CG2 3.83Å; M601-V610 HydrophobicContact CG-CG1 4.47Å; M601-V610 HydrophobicContact CG-CG2 3.82Å; V610-I614 HydrophobicContact CG1-CD1 3.83Å; V610-I614 WeakPolarHBondContact O-CB 3.44Å; V610-I614 WeakPolarHBondContact O-CD1 3.44Å; V610-I614 WeakPolarHBondContact O-CG1 3.24Å; V610-I614 PolarHBondContact O-N 2.93Å; V610-L621 HydrophobicContact CG1-CD1 4.01Å; V610-F644 HydrophobicContact CG1-CE1 3.8Å; V610-F644 HydrophobicContact CG1-CZ 3.74Å
611F92.7Very high79.3Confident0 Ų041.1 Ų41.10%025%0.25CC..Hα-helixtrans-67.6-50.7176.3-71.6-68000111.3F498 E594 L597 S609 Q613 I614 L615 A647 L651 M685 A689F498-F611 HydrophobicContact CE2-CB 3.7Å; F498-F611 HydrophobicContact CZ-CB 4.19Å; E594-F611 HydrophobicContact CB-CD2 4.21Å; E594-F611 HydrophobicContact CB-CE2 4.45Å; E594-F611 HydrophobicContact CG-CD2 4.08Å; L597-F611 HydrophobicContact CB-CE2 4.39Å; L597-F611 HydrophobicContact CD2-CD2 4.25Å; L597-F611 HydrophobicContact CD2-CE1 4Å; L597-F611 HydrophobicContact CD2-CE2 3.52Å; L597-F611 HydrophobicContact CD2-CZ 3.38Å; S609-F611 PolarHBondContact O-N 3.22Å; S609-F611 PolarHBondContact OG-N 3.38Å; F611-Q613 VanDerWaalsContact C-N 3.28Å; F611-Q613 PolarHBondContact O-N 3.03Å; F611-I614 PolarHBondContact O-N 3.48Å; F611-I614 VanDerWaalsContact O-N 3.09Å; F611-L615 WeakPolarHBondContact O-CG 3.26Å; F611-L615 PolarHBondContact O-N 3.3Å; F611-A647 HydrophobicContact CZ-CB 4.41Å; F611-L651 HydrophobicContact CE1-CD1 4.47Å; F611-L651 HydrophobicContact CZ-CD1 4.04Å; F611-M685 HydrophobicContact CD1-CB 4.08Å; F611-M685 HydrophobicContact CD1-CG 4.23Å; F611-M685 HydrophobicContact CD2-CE 3.62Å; F611-M685 HydrophobicContact CD2-CG 4.43Å; F611-M685 HydrophobicContact CE1-CB 4Å; F611-M685 WeakPolarHBondContact CE1-O 3.13Å; F611-M685 HydrophobicContact CE2-CE 3.45Å; F611-M685 VanDerWaalsContact CE2-CE 3.45Å; F611-M685 HydrophobicContact CG-CB 4.49Å; F611-M685 HydrophobicContact CG-CE 4.29Å; F611-M685 HydrophobicContact CG-CG 4.17Å; F611-M685 HydrophobicContact CZ-CB 4.31Å; F611-M685 HydrophobicContact CZ-CE 4.03Å; F611-A689 HydrophobicContact CE1-CB 4.06Å
612V91.2Very high79Confident4 Ų445.1 Ų45.12%0.02427%0.268CS..Hα-helixtrans-56.8-43.7176.9171.40000111.1G496 F498 V608 S609 I614 L615 L616G496-V612 VanDerWaalsContact O-CG2 3.3Å; G496-V612 WeakPolarHBondContact O-CG2 3.35Å; F498-V612 HydrophobicContact CD1-CG2 3.87Å; F498-V612 HydrophobicContact CE1-CG2 3.33Å; F498-V612 HydrophobicContact CZ-CG2 3.68Å; V608-V612 HydrophobicContact CB-CB 4.28Å; V608-V612 HydrophobicContact CB-CG1 4Å; V608-V612 HydrophobicContact CG1-CG1 4.31Å; V608-V612 HydrophobicContact CG2-CG1 4.46Å; S609-V612 PolarHBondContact O-N 3.47Å; S609-V612 WeakPolarHBondContact OG-CG2 3.4Å; S609-V612 PolarHBondContact OG-N 2.89Å; V612-I614 VanDerWaalsContact C-N 3.35Å; V612-I614 PolarHBondContact O-N 3.15Å; V612-L615 PolarHBondContact O-N 3Å; V612-L616 HydrophobicContact CG1-CD1 3.68Å; V612-L616 HydrophobicContact CG1-CG 4.2Å; V612-L616 WeakPolarHBondContact O-CB 3.42Å; V612-L616 WeakPolarHBondContact O-CG 3.32Å; V612-L616 PolarHBondContact O-N 3.33Å
613Q88.6Confident79.3Confident34 Ų3443.7 Ų43.716%0.15925%0.253CS..Hα-helixtrans-57.5-46.6175.6-172175.717.500111.9V608 S609 F611 L615 L616 N617 C620V608-Q613 HydrophobicContact CG2-CB 4.08Å; S609-Q613 PolarHBondContact O-N 3.15Å; F611-Q613 VanDerWaalsContact C-N 3.28Å; F611-Q613 PolarHBondContact O-N 3.03Å; Q613-L615 VanDerWaalsContact C-N 3.34Å; Q613-L615 PolarHBondContact O-N 3.37Å; Q613-L616 PolarHBondContact O-N 2.88Å; Q613-N617 CarbonylContact O-C 3.53Å; Q613-N617 WeakPolarHBondContact O-CA 3.32Å; Q613-N617 PolarHBondContact O-N 3.46Å; Q613-N617 VanDerWaalsContact O-O 3.05Å; Q613-C620 PolarHBondContact NE2-O 2.86Å
614I89.6Confident79.6Confident0 Ų037.1 Ų37.10%022%0.219CC..Hα-helixtrans-63.8-38.8178.4-71.3167.6000111.9V610 F611 V612 P618 L621 F644 L691V610-I614 HydrophobicContact CG1-CD1 3.83Å; V610-I614 WeakPolarHBondContact O-CB 3.44Å; V610-I614 WeakPolarHBondContact O-CD1 3.44Å; V610-I614 WeakPolarHBondContact O-CG1 3.24Å; V610-I614 PolarHBondContact O-N 2.93Å; F611-I614 PolarHBondContact O-N 3.48Å; F611-I614 VanDerWaalsContact O-N 3.09Å; V612-I614 VanDerWaalsContact C-N 3.35Å; V612-I614 PolarHBondContact O-N 3.15Å; I614-P618 HydrophobicContact CG2-CB 4.41Å; I614-P618 VanDerWaalsContact O-CD 3.27Å; I614-P618 WeakPolarHBondContact O-CD 3.36Å; I614-L621 HydrophobicContact CD1-CD2 4Å; I614-L621 HydrophobicContact CG1-CD1 4.23Å; I614-L621 HydrophobicContact CG1-CD2 3.93Å; I614-F644 HydrophobicContact CD1-CE1 3.68Å; I614-F644 HydrophobicContact CD1-CZ 3.9Å; I614-L691 HydrophobicContact CG2-CB 4.19Å; I614-L691 HydrophobicContact CG2-CD2 3.7Å; I614-L691 HydrophobicContact CG2-CG 4.06Å
615L89.6Confident79.4Confident3 Ų338.3 Ų38.32%0.01623%0.231CC..Hα-helixtrans-72.1-39.8-179.1-61-170.8000112.5F498 F611 V612 Q613 M684 M756 L760F498-L615 HydrophobicContact CE1-CD1 4.31Å; F498-L615 HydrophobicContact CE2-CD1 4.46Å; F498-L615 HydrophobicContact CZ-CD1 3.57Å; F611-L615 WeakPolarHBondContact O-CG 3.26Å; F611-L615 PolarHBondContact O-N 3.3Å; V612-L615 PolarHBondContact O-N 3Å; Q613-L615 VanDerWaalsContact C-N 3.34Å; Q613-L615 PolarHBondContact O-N 3.37Å; L615-M684 HydrophobicContact CB-CE 4.5Å; L615-M684 HydrophobicContact CD1-CE 3.92Å; L615-M684 HydrophobicContact CD1-CG 3.38Å; L615-M684 HydrophobicContact CD1-SD 4.35Å; L615-M684 HydrophobicContact CD2-CE 3.58Å; L615-M684 HydrophobicContact CD2-CG 3.67Å; L615-M684 HydrophobicContact CD2-SD 3.75Å; L615-M684 HydrophobicContact CG-CE 4.15Å; L615-M684 HydrophobicContact CG-CG 4.13Å; L615-M756 HydrophobicContact CB-SD 4.48Å; L615-L760 HydrophobicContact CD2-CD2 4.28Å
616L88.9Confident79.1Confident88 Ų8841.8 Ų41.846%0.46123%0.228SC..Hα-helixtrans-79.6-46.5-178.8-65.2179.6000112V612 Q613 M756V612-L616 HydrophobicContact CG1-CD1 3.68Å; V612-L616 HydrophobicContact CG1-CG 4.2Å; V612-L616 WeakPolarHBondContact O-CB 3.42Å; V612-L616 WeakPolarHBondContact O-CG 3.32Å; V612-L616 PolarHBondContact O-N 3.33Å; Q613-L616 PolarHBondContact O-N 2.88Å; L616-M756 HydrophobicContact CD2-SD 4.38Å
617N86.9Confident78.5Confident62 Ų6241.8 Ų41.833%0.33223%0.228SC..  trans-156.292178.8-169.1-7.8000112.3Q613 D619 C620Q613-N617 CarbonylContact O-C 3.53Å; Q613-N617 WeakPolarHBondContact O-CA 3.32Å; Q613-N617 PolarHBondContact O-N 3.46Å; Q613-N617 VanDerWaalsContact O-O 3.05Å; N617-D619 VanDerWaalsContact C-N 3.26Å; N617-D619 PolarHBondContact O-N 3.25Å; N617-D619 PolarHBondContact OD1-N 2.7Å; N617-C620 HydrophobicContact CB-CB 4.34Å; N617-C620 PolarHBondContact ND2-SG 3.07Å; N617-C620 PolarHBondContact O-N 3.06Å
618P86.5Confident77.3Confident0 Ų042.6 Ų42.60%024%0.236CC..G310 helixtrans-66.6-22.4-177.727.1-34.4000114.3I614 C620 L621 L691 L695 N712 V715 L760I614-P618 HydrophobicContact CG2-CB 4.41Å; I614-P618 VanDerWaalsContact O-CD 3.27Å; I614-P618 WeakPolarHBondContact O-CD 3.36Å; P618-C620 VanDerWaalsContact C-N 3.29Å; P618-L621 VanDerWaalsContact O-CB 3.28Å; P618-L621 WeakPolarHBondContact O-CB 3.49Å; P618-L621 PolarHBondContact O-N 3.37Å; P618-L691 HydrophobicContact CB-CD2 3.78Å; P618-L691 HydrophobicContact CB-CG 4.39Å; P618-L691 HydrophobicContact CG-CD2 4.18Å; P618-L695 HydrophobicContact CB-CD1 4.3Å; P618-N712 PolarHBondContact O-ND2 3.4Å; P618-V715 HydrophobicContact CB-CG2 3.74Å; P618-V715 HydrophobicContact CG-CG2 3.43Å; P618-V715 VanDerWaalsContact CG-CG2 3.43Å; P618-L760 HydrophobicContact CG-CD1 4.03Å
619D82.2Confident75.7Confident62 Ų6246 Ų4633%0.33226%0.256SS..G310 helixtrans-72.7-26.3178.5-68.9-19.5000111.8N617 L621 N712 G714 V715N617-D619 VanDerWaalsContact C-N 3.26Å; N617-D619 PolarHBondContact O-N 3.25Å; N617-D619 PolarHBondContact OD1-N 2.7Å; D619-L621 PolarHBondContact O-N 3.2Å; D619-N712 PolarHBondContact O-ND2 2.95Å; D619-G714 WeakPolarHBondContact OD1-CA 3.28Å; D619-V715 WeakPolarHBondContact OD1-CG2 3.43Å; D619-V715 PolarHBondContact OD1-N 3.31Å
620C79.3Confident73.8Confident73 Ų7352.1 Ų52.149%0.49329%0.289SS..G310 helixtrans-79.7-0.3174.6-72.60000113.5Q613 N617 P618 E622Q613-C620 PolarHBondContact NE2-O 2.86Å; N617-C620 HydrophobicContact CB-CB 4.34Å; N617-C620 PolarHBondContact ND2-SG 3.07Å; N617-C620 PolarHBondContact O-N 3.06Å; P618-C620 VanDerWaalsContact C-N 3.29Å; C620-E622 PolarHBondContact O-N 3.17Å
621L80.1Confident71.9Confident5 Ų556 Ų563%0.02631%0.314CS..  trans-65.9117179-179.168.2000111.1V610 I614 P618 D619 L623 F644 L695 N712V610-L621 HydrophobicContact CG1-CD1 4.01Å; I614-L621 HydrophobicContact CD1-CD2 4Å; I614-L621 HydrophobicContact CG1-CD1 4.23Å; I614-L621 HydrophobicContact CG1-CD2 3.93Å; P618-L621 VanDerWaalsContact O-CB 3.28Å; P618-L621 WeakPolarHBondContact O-CB 3.49Å; P618-L621 PolarHBondContact O-N 3.37Å; D619-L621 PolarHBondContact O-N 3.2Å; L621-L623 HydrophobicContact CD2-CD2 3.7Å; L621-L623 HydrophobicContact CD2-CG 4.46Å; L621-L623 HydrophobicContact CG-CD2 4.07Å; L621-L623 PolarHBondContact O-N 3.13Å; L621-F644 HydrophobicContact CD2-CZ 4.15Å; L621-L695 HydrophobicContact CD2-CD1 4.01Å; L621-N712 WeakPolarHBondContact O-CB 3.29Å; L621-N712 PolarHBondContact O-ND2 2.96Å; L621-N712 VanDerWaalsContact O-ND2 3.07Å
622E72.4Confident70.2Confident93 Ų9356.8 Ų56.844%0.43532%0.318SS..  trans-82.693.2179.7-65.4-170.1175.500112.7R604 C620 G624R604-E622 WeakPolarHBondContact CD-OE2 3.47Å; R604-E622 PolarHBondContact NH1-O 3.5Å; R604-E622 IonicContact NH1-OE2 3.84Å; C620-E622 PolarHBondContact O-N 3.17Å; E622-G624 VanDerWaalsContact C-N 3.26Å; E622-G624 PolarHBondContact O-N 2.92Å
623L72Confident68.7Low4 Ų459.5 Ų59.52%0.02134%0.338CS..  trans-73.1-9.1179.7-63.3176000114.9M601 L621 L637 H640 L695 N712M601-L623 HydrophobicContact CE-CD2 3.95Å; L621-L623 HydrophobicContact CD2-CD2 3.7Å; L621-L623 HydrophobicContact CD2-CG 4.46Å; L621-L623 HydrophobicContact CG-CD2 4.07Å; L621-L623 PolarHBondContact O-N 3.13Å; L623-L637 HydrophobicContact CB-CD1 4.16Å; L623-L637 HydrophobicContact CD1-CD1 4.11Å; L623-H640 PolarHBondContact O-CE1 3.38Å; L623-H640 PolarHBondContact O-ND1 3.48Å; L623-L695 HydrophobicContact CD1-CB 4.13Å; L623-N712 HydrophobicContact CD1-CB 4.19Å; L623-N712 HydrophobicContact CG-CB 4.45Å
624G61.1Low67.6Low5 Ų562.5 Ų62.55%0.05235%0.348CS..SBendtrans-169.2163.1179.100000113.7R604 E622 F626R604-G624 VanDerWaalsContact NH1-CA 3.26Å; R604-G624 VanDerWaalsContact NH1-N 3.18Å; R604-G624 PolarHBondContact NH1-O 2.83Å; E622-G624 VanDerWaalsContact C-N 3.26Å; E622-G624 PolarHBondContact O-N 2.92Å; G624-F626 PolarHBondContact O-N 2.88Å
625N52.5Low66.8Low96 Ų9666 Ų6651%0.51337%0.373SS..  trans-72.5124.2174.2-76.5-5.3000109.8R604 S627 I632R604-N625 WeakPolarHBondContact CD-OD1 3.33Å; R604-N625 PolarHBondContact NE-OD1 2.87Å; N625-S627 PolarHBondContact O-N 3.15Å; N625-I632 WeakPolarHBondContact O-CG1 3.36Å
626F47.3Very low66.2Low135 Ų13567.7 Ų67.759%0.59238%0.383SS*.  trans-7833.4167.8-63.5-77.3000112.5G624 P628 V708G624-F626 PolarHBondContact O-N 2.88Å; F626-P628 WeakPolarHBondContact O-CD 3.5Å; F626-V708 HydrophobicContact CE1-CG1 4.49Å
627S47.6Very low65.7Low46 Ų4663.7 Ų63.732%0.32236%0.362SS..  trans-76123.6177.4-1770000109.3N625 V629 N630N625-S627 PolarHBondContact O-N 3.15Å; S627-V629 PolarHBondContact O-N 3.43Å; S627-V629 VanDerWaalsContact O-N 3.15Å; S627-V629 PolarHBondContact OG-N 3.4Å; S627-N630 CarbonylContact O-C 3.49Å; S627-N630 PolarHBondContact O-N 2.81Å
628P49.5Very low65.6Low128 Ų12864.3 Ų64.383%0.83137%0.372SS*.THydrogen-bonded Turntrans-63.6-15.8172.723.4-30.9000112.9F626F626-P628 WeakPolarHBondContact O-CD 3.5Å
629V52Low65.5Low118 Ų11870 Ų7072%0.71539%0.393SS*.THydrogen-bonded Turntrans-84.5-29.2-176.9-172.20000112.5S627S627-V629 PolarHBondContact O-N 3.43Å; S627-V629 VanDerWaalsContact O-N 3.15Å; S627-V629 PolarHBondContact OG-N 3.4Å
630N50.1Low65.8Low129 Ų12967.1 Ų67.169%0.6938%0.377SS*.SBendtrans-132.879.4176.5-85.4-34.3000108.9S627S627-N630 CarbonylContact O-C 3.49Å; S627-N630 PolarHBondContact O-N 2.81Å
631P50.1Low66.3Low91 Ų9166.3 Ų66.359%0.59137%0.366SS*.PPolyproline II helixtrans-59.2141177.822.8-31.4000110.8S633P631-S633 PolarHBondContact O-N 3.1Å
632I56.2Low66.8Low16 Ų1668.5 Ų68.58%0.08238%0.379CS..PPolyproline II helixtrans-56.9133.8-174.5-56.8162.9000110.3N625 N709 V710N625-I632 WeakPolarHBondContact O-CG1 3.36Å; I632-N709 WeakPolarHBondContact O-CB 3.49Å; I632-N709 PolarHBondContact O-ND2 3.19Å; I632-V710 HydrophobicContact CB-CB 4Å; I632-V710 HydrophobicContact CB-CG2 4.08Å; I632-V710 HydrophobicContact CD1-CB 3.72Å; I632-V710 HydrophobicContact CD1-CG1 4.23Å; I632-V710 WeakPolarHBondContact CD1-O 3.34Å; I632-V710 HydrophobicContact CG1-CB 4.45Å; I632-V710 HydrophobicContact CG2-CB 3.62Å; I632-V710 HydrophobicContact CG2-CG1 4.23Å; I632-V710 HydrophobicContact CG2-CG2 3.42Å; I632-V710 VanDerWaalsContact CG2-CG2 3.42Å
633S60.1Low67.8Low61 Ų6167.1 Ų67.143%0.42737%0.37SS..PPolyproline II helixtrans-92.8142.8168.21790000110.1P631 S635 T636P631-S633 PolarHBondContact O-N 3.1Å; S633-S635 WeakPolarHBondContact CB-OG 3.46Å; S633-S635 PolarHBondContact O-N 2.96Å; S633-S635 PolarHBondContact OG-N 3Å; S633-S635 PolarHBondContact OG-OG 2.93Å; S633-T636 WeakPolarHBondContact O-CB 3.41Å; S633-T636 PolarHBondContact O-N 3.28Å
634Y64.9Low68.9Low98 Ų9866.9 Ų66.938%0.38437%0.369SS..Hα-helixtrans-46.8-29.1167.8-77.7-84.1000112.8T636 L637 S638 T700 N701 N704Y634-T636 VanDerWaalsContact C-N 3.31Å; Y634-T636 PolarHBondContact O-N 3.39Å; Y634-L637 PolarHBondContact O-N 2.94Å; Y634-S638 WeakPolarHBondContact O-CB 3.45Å; Y634-S638 PolarHBondContact O-N 2.97Å; Y634-T700 HydrophobicContact CD1-CG2 4.42Å; Y634-T700 HydrophobicContact CE1-CG2 4.37Å; Y634-N701 PolarHBondContact OH-O 3.24Å; Y634-N704 PolarHBondContact OH-OD1 3.07Å
635S72.5Confident70.6Confident74 Ų7470 Ų7052%0.51738%0.383SS..Hα-helixtrans-61.2-35.5176.363.40000113.3S633 R639S633-S635 WeakPolarHBondContact CB-OG 3.46Å; S633-S635 PolarHBondContact O-N 2.96Å; S633-S635 PolarHBondContact OG-N 3Å; S633-S635 PolarHBondContact OG-OG 2.93Å; S635-R639 VanDerWaalsContact O-CB 3.25Å; S635-R639 WeakPolarHBondContact O-CB 3.43Å; S635-R639 PolarHBondContact O-N 2.82Å
636T77.4Confident72.6Confident37 Ų3771.7 Ų71.723%0.22739%0.385CS..Hα-helixtrans-67.6-43.7179.4-61.30000111.1S633 Y634 R639 H640S633-T636 WeakPolarHBondContact O-CB 3.41Å; S633-T636 PolarHBondContact O-N 3.28Å; Y634-T636 VanDerWaalsContact C-N 3.31Å; Y634-T636 PolarHBondContact O-N 3.39Å; T636-R639 WeakPolarHBondContact O-CB 3.27Å; T636-R639 PolarHBondContact O-N 2.91Å; T636-H640 VanDerWaalsContact CG2-CE1 3.43Å; T636-H640 WeakPolarHBondContact CG2-CE1 3.42Å; T636-H640 PolarHBondContact O-N 2.92Å
637L79.3Confident75Confident4 Ų465.7 Ų65.72%0.02136%0.361CS..Hα-helixtrans-68.4-42.4179.6-166.263.9000111.8L623 Y634 R639 H640 F641 C696 T700 V710L623-L637 HydrophobicContact CB-CD1 4.16Å; L623-L637 HydrophobicContact CD1-CD1 4.11Å; Y634-L637 PolarHBondContact O-N 2.94Å; L637-R639 PolarHBondContact O-N 3.13Å; L637-H640 PolarHBondContact O-N 3.32Å; L637-F641 WeakPolarHBondContact O-CB 3.48Å; L637-F641 PolarHBondContact O-N 2.83Å; L637-C696 HydrophobicContact CD1-CB 3.94Å; L637-C696 WeakPolarHBondContact CD2-O 3.39Å; L637-C696 HydrophobicContact CG-CB 4.25Å; L637-C696 WeakPolarHBondContact CG-O 3.47Å; L637-T700 HydrophobicContact CD2-CG2 3.58Å; L637-V710 HydrophobicContact CD1-CG1 4Å; L637-V710 HydrophobicContact CD2-CG1 4.07Å; L637-V710 HydrophobicContact CD2-CG2 4.13Å
638S83.7Confident77.4Confident76 Ų7666.5 Ų66.553%0.53136%0.357SS..Hα-helixtrans-59.7-36.5172.5-178.90000112Y634 T642Y634-S638 WeakPolarHBondContact O-CB 3.45Å; Y634-S638 PolarHBondContact O-N 2.97Å; S638-T642 PolarHBondContact O-N 2.92Å; S638-T642 VanDerWaalsContact O-N 3.08Å; S638-T642 PolarHBondContact O-OG1 3.21Å
639R85.2Confident79.7Confident119 Ų11963.6 Ų63.645%0.44933%0.333SS..Hα-helixtrans-68.5-45.9175.2-169-177.567170.22.4112S635 T636 L637 F641 T642 Y643S635-R639 VanDerWaalsContact O-CB 3.25Å; S635-R639 WeakPolarHBondContact O-CB 3.43Å; S635-R639 PolarHBondContact O-N 2.82Å; T636-R639 WeakPolarHBondContact O-CB 3.27Å; T636-R639 PolarHBondContact O-N 2.91Å; L637-R639 PolarHBondContact O-N 3.13Å; R639-F641 PolarHBondContact O-N 2.97Å; R639-T642 WeakPolarHBondContact O-CB 3.43Å; R639-T642 PolarHBondContact O-N 3.09Å; R639-T642 VanDerWaalsContact O-N 3.13Å; R639-Y643 WeakPolarHBondContact CD-OH 3.48Å; R639-Y643 HydrophobicContact CG-CD2 4.16Å; R639-Y643 HydrophobicContact CG-CE1 4.47Å; R639-Y643 HydrophobicContact CG-CE2 3.44Å; R639-Y643 VanDerWaalsContact CG-CE2 3.44Å; R639-Y643 WeakPolarHBondContact O-CD2 3.34Å; R639-Y643 PolarHBondContact O-N 2.99Å
640H87.6Confident81.8Confident1 Ų160.5 Ų60.51%0.00531%0.311CS..Hα-helixtrans-60.7-44.1175.3-65.5159.6000112.1M601 L623 T636 L637 T642 Y643 F644M601-H640 HydrophobicContact CE-CB 4.19Å; M601-H640 HydrophobicContact SD-CB 3.78Å; M601-H640 PolarHBondContact SD-CD2 2.93Å; L623-H640 PolarHBondContact O-CE1 3.38Å; L623-H640 PolarHBondContact O-ND1 3.48Å; T636-H640 VanDerWaalsContact CG2-CE1 3.43Å; T636-H640 WeakPolarHBondContact CG2-CE1 3.42Å; T636-H640 PolarHBondContact O-N 2.92Å; L637-H640 PolarHBondContact O-N 3.32Å; H640-T642 VanDerWaalsContact C-N 3.26Å; H640-T642 PolarHBondContact O-N 3.08Å; H640-Y643 PolarHBondContact O-N 3.04Å; H640-Y643 VanDerWaalsContact O-N 3.11Å; H640-F644 VanDerWaalsContact O-CD2 3.26Å; H640-F644 WeakPolarHBondContact O-CD2 3.33Å; H640-F644 PolarHBondContact O-N 3.24Å
641F90.4Very high84.1Confident57 Ų5754.3 Ų54.325%0.2528%0.278CS..Hα-helixtrans-52.3-47.7171.9175.5-89.8000111.3L637 R639 Y643 F644 Q645 Q693 C696 I697L637-F641 WeakPolarHBondContact O-CB 3.48Å; L637-F641 PolarHBondContact O-N 2.83Å; R639-F641 PolarHBondContact O-N 2.97Å; F641-Y643 PolarHBondContact O-N 3.07Å; F641-F644 PolarHBondContact O-N 3.44Å; F641-Q645 WeakPolarHBondContact O-CB 3.41Å; F641-Q645 PolarHBondContact O-N 2.92Å; F641-Q693 HydrophobicContact CD2-CB 4.08Å; F641-Q693 HydrophobicContact CD2-CG 3.85Å; F641-Q693 HydrophobicContact CE2-CB 3.93Å; F641-Q693 HydrophobicContact CE2-CG 3.73Å; F641-Q693 HydrophobicContact CZ-CG 4.34Å; F641-C696 HydrophobicContact CB-CB 3.92Å; F641-C696 HydrophobicContact CD2-CB 4.39Å; F641-I697 HydrophobicContact CD2-CD1 4.27Å; F641-I697 HydrophobicContact CD2-CG1 3.94Å; F641-I697 HydrophobicContact CE2-CD1 3.69Å; F641-I697 HydrophobicContact CE2-CG1 3.84Å
642T91.7Very high86.4Confident50 Ų5052.9 Ų52.931%0.30726%0.264SS..Hα-helixtrans-62.9-39.4178.8-56.30000112.2S638 R639 H640 Q645 K646S638-T642 PolarHBondContact O-N 2.92Å; S638-T642 VanDerWaalsContact O-N 3.08Å; S638-T642 PolarHBondContact O-OG1 3.21Å; R639-T642 WeakPolarHBondContact O-CB 3.43Å; R639-T642 PolarHBondContact O-N 3.09Å; R639-T642 VanDerWaalsContact O-N 3.13Å; H640-T642 VanDerWaalsContact C-N 3.26Å; H640-T642 PolarHBondContact O-N 3.08Å; T642-Q645 PolarHBondContact O-N 3.45Å; T642-K646 HydrophobicContact CG2-CD 4.4Å; T642-K646 WeakPolarHBondContact O-CG 3.4Å; T642-K646 PolarHBondContact O-N 3.28Å
643Y92.5Very high88.4Confident64 Ų6458.4 Ų58.425%0.25128%0.283SS..Hα-helixtrans-65.8-45177-65.8-43.6000112.3T600 R639 H640 F641 Q645 K646 A647T600-Y643 HydrophobicContact CG2-CD1 4.4Å; T600-Y643 HydrophobicContact CG2-CD2 4.39Å; T600-Y643 HydrophobicContact CG2-CE1 4.16Å; T600-Y643 HydrophobicContact CG2-CE2 4.13Å; R639-Y643 WeakPolarHBondContact CD-OH 3.48Å; R639-Y643 HydrophobicContact CG-CD2 4.16Å; R639-Y643 HydrophobicContact CG-CE1 4.47Å; R639-Y643 HydrophobicContact CG-CE2 3.44Å; R639-Y643 VanDerWaalsContact CG-CE2 3.44Å; R639-Y643 WeakPolarHBondContact O-CD2 3.34Å; R639-Y643 PolarHBondContact O-N 2.99Å; H640-Y643 PolarHBondContact O-N 3.04Å; H640-Y643 VanDerWaalsContact O-N 3.11Å; F641-Y643 PolarHBondContact O-N 3.07Å; Y643-Q645 VanDerWaalsContact C-N 3.31Å; Y643-Q645 PolarHBondContact O-N 2.98Å; Y643-K646 PolarHBondContact O-N 3.03Å; Y643-A647 WeakPolarHBondContact O-CB 3.45Å; Y643-A647 PolarHBondContact O-N 2.93Å
644F95.1Very high90.1Very high0 Ų055.6 Ų55.60%026%0.263CS..Hα-helixtrans-60.9-40.4172.9-78.8-64.4000112.1L597 M601 V610 I614 L621 H640 F641 A647 R648 A689 Q693L597-F644 HydrophobicContact CD1-CD1 4.18Å; L597-F644 HydrophobicContact CD1-CE1 4.37Å; L597-F644 HydrophobicContact CD1-CG 4.49Å; L597-F644 HydrophobicContact CD2-CD1 3.79Å; L597-F644 HydrophobicContact CD2-CE1 3.72Å; L597-F644 HydrophobicContact CG-CE1 4.46Å; M601-F644 HydrophobicContact CE-CE2 3.89Å; M601-F644 HydrophobicContact CE-CZ 4.15Å; M601-F644 HydrophobicContact SD-CE2 4.14Å; M601-F644 HydrophobicContact SD-CZ 4.49Å; V610-F644 HydrophobicContact CG1-CE1 3.8Å; V610-F644 HydrophobicContact CG1-CZ 3.74Å; I614-F644 HydrophobicContact CD1-CE1 3.68Å; I614-F644 HydrophobicContact CD1-CZ 3.9Å; L621-F644 HydrophobicContact CD2-CZ 4.15Å; H640-F644 VanDerWaalsContact O-CD2 3.26Å; H640-F644 WeakPolarHBondContact O-CD2 3.33Å; H640-F644 PolarHBondContact O-N 3.24Å; F641-F644 PolarHBondContact O-N 3.44Å; F644-A647 PolarHBondContact O-N 3.49Å; F644-R648 VanDerWaalsContact O-CB 3.31Å; F644-R648 WeakPolarHBondContact O-CB 3.43Å; F644-R648 PolarHBondContact O-N 3.38Å; F644-A689 HydrophobicContact CD1-CB 4.38Å; F644-Q693 HydrophobicContact CB-CG 3.71Å; F644-Q693 PolarHBondContact O-NE2 3.46Å
645Q96.1Very high91.7Very high70 Ų7052.1 Ų52.133%0.32725%0.251SS..Hα-helixtrans-62-45.3176.1-174.2-178.77.300111.7F641 T642 Y643 R648 I649F641-Q645 WeakPolarHBondContact O-CB 3.41Å; F641-Q645 PolarHBondContact O-N 2.92Å; T642-Q645 PolarHBondContact O-N 3.45Å; Y643-Q645 VanDerWaalsContact C-N 3.31Å; Y643-Q645 PolarHBondContact O-N 2.98Å; Q645-R648 PolarHBondContact O-N 3.29Å; Q645-I649 HydrophobicContact CG-CD1 4.11Å; Q645-I649 WeakPolarHBondContact O-CG1 3.41Å; Q645-I649 PolarHBondContact O-N 3.45Å
646K96.2Very high92.8Very high132 Ų13252.4 Ų52.457%0.57425%0.246SC*.Hα-helixtrans-62.5-48.2176.2-75.7178.9178-175.70111.8T642 Y643 R648 I649 E650T642-K646 HydrophobicContact CG2-CD 4.4Å; T642-K646 WeakPolarHBondContact O-CG 3.4Å; T642-K646 PolarHBondContact O-N 3.28Å; Y643-K646 PolarHBondContact O-N 3.03Å; K646-R648 VanDerWaalsContact C-N 3.3Å; K646-R648 PolarHBondContact O-N 2.93Å; K646-I649 PolarHBondContact O-N 3.27Å; K646-E650 PolarHBondContact O-N 3.03Å
647A96.7Very high93.6Very high9 Ų955.2 Ų55.27%0.07425%0.253CS..Hα-helixtrans-56.4-46176.400000111I593 L597 F611 Y643 F644 I649 E650 L651I593-A647 HydrophobicContact CG2-CB 3.74Å; L597-A647 HydrophobicContact CD2-CB 4.3Å; F611-A647 HydrophobicContact CZ-CB 4.41Å; Y643-A647 WeakPolarHBondContact O-CB 3.45Å; Y643-A647 PolarHBondContact O-N 2.93Å; F644-A647 PolarHBondContact O-N 3.49Å; A647-I649 PolarHBondContact O-N 3.03Å; A647-E650 PolarHBondContact O-N 3.45Å; A647-L651 WeakPolarHBondContact O-CB 3.25Å; A647-L651 WeakPolarHBondContact O-CD1 3.46Å; A647-L651 WeakPolarHBondContact O-CG 3.49Å; A647-L651 PolarHBondContact O-N 2.94Å
648R97.7Very high94.3Very high62 Ų6255 Ų5523%0.23425%0.252CS..Hα-helixtrans-59.4-44.5177-172.2-177.763.172.9-4.4112.9F644 Q645 K646 Q652 I686 A689 R690F644-R648 VanDerWaalsContact O-CB 3.31Å; F644-R648 WeakPolarHBondContact O-CB 3.43Å; F644-R648 PolarHBondContact O-N 3.38Å; Q645-R648 PolarHBondContact O-N 3.29Å; K646-R648 VanDerWaalsContact C-N 3.3Å; K646-R648 PolarHBondContact O-N 2.93Å; R648-Q652 WeakPolarHBondContact O-CB 3.23Å; R648-Q652 PolarHBondContact O-N 3.3Å; R648-I686 HydrophobicContact CG-CG2 4.23Å; R648-A689 HydrophobicContact CB-CB 3.89Å; R648-A689 HydrophobicContact CG-CB 4.49Å; R648-R690 VanDerWaalsContact CD-CG 3.48Å; R648-R690 HydrophobicContact CG-CG 4.48Å
649I97.8Very high94.7Very high67 Ų6754 Ų5434%0.34424%0.239SC..Hα-helixtrans-65.3-43.4180-69.6165.7000110.5Q645 K646 A647 Q652 R653Q645-I649 HydrophobicContact CG-CD1 4.11Å; Q645-I649 WeakPolarHBondContact O-CG1 3.41Å; Q645-I649 PolarHBondContact O-N 3.45Å; K646-I649 PolarHBondContact O-N 3.27Å; A647-I649 PolarHBondContact O-N 3.03Å; I649-Q652 PolarHBondContact O-N 3.31Å; I649-R653 WeakPolarHBondContact O-CG 3.3Å; I649-R653 PolarHBondContact O-N 2.95Å; I649-R653 VanDerWaalsContact O-N 3.11Å
650E97.4Very high95Very high53 Ų5353.2 Ų53.225%0.24825%0.247CC..Hα-helixtrans-71.7-36.6-179.1-162.659.2-144.400112.4I593 K646 A647 Q652 R653 C654I593-E650 HydrophobicContact CD1-CB 3.84Å; I593-E650 HydrophobicContact CD1-CG 3.65Å; I593-E650 HydrophobicContact CG1-CB 4.35Å; I593-E650 HydrophobicContact CG1-CG 4.16Å; K646-E650 PolarHBondContact O-N 3.03Å; A647-E650 PolarHBondContact O-N 3.45Å; E650-Q652 VanDerWaalsContact C-N 3.32Å; E650-Q652 PolarHBondContact O-N 3.22Å; E650-R653 WeakPolarHBondContact O-CB 3.45Å; E650-R653 PolarHBondContact O-N 3.29Å; E650-R653 WeakPolarHBondContact OE2-CD 3.41Å; E650-R653 IonicContact OE2-CZ 3.32Å; E650-R653 IonicContact OE2-NE 3.36Å; E650-R653 IonicContact OE2-NH1 3.8Å; E650-R653 PolarHBondContact OE2-NH1 2.85Å; E650-C654 PolarHBondContact O-N 2.92Å; E650-C654 PolarHBondContact O-SG 2.87Å
651L98.1Very high95Very high0 Ų053.9 Ų53.90%025%0.253CS..Hα-helixtrans-63-38.3171.2-72.5165.8000111.9M590 I593 F611 A647 R653 C654 H655 I682 M685 I686M590-L651 HydrophobicContact CG-CD2 4.28Å; I593-L651 HydrophobicContact CD1-CD2 3.99Å; I593-L651 HydrophobicContact CD1-CG 4.12Å; I593-L651 HydrophobicContact CG2-CD1 4.36Å; I593-L651 HydrophobicContact CG2-CD2 4.41Å; I593-L651 HydrophobicContact CG2-CG 4.13Å; F611-L651 HydrophobicContact CE1-CD1 4.47Å; F611-L651 HydrophobicContact CZ-CD1 4.04Å; A647-L651 WeakPolarHBondContact O-CB 3.25Å; A647-L651 WeakPolarHBondContact O-CD1 3.46Å; A647-L651 WeakPolarHBondContact O-CG 3.49Å; A647-L651 PolarHBondContact O-N 2.94Å; L651-R653 VanDerWaalsContact C-N 3.33Å; L651-R653 PolarHBondContact O-N 3.1Å; L651-C654 WeakPolarHBondContact O-CB 3.45Å; L651-C654 PolarHBondContact O-N 3.48Å; L651-H655 PolarHBondContact O-N 2.85Å; L651-I682 HydrophobicContact CB-CG2 4.27Å; L651-I682 HydrophobicContact CD2-CG2 4.4Å; L651-I682 WeakPolarHBondContact O-CG2 3.21Å; L651-M685 HydrophobicContact CD1-CB 3.59Å; L651-M685 HydrophobicContact CD1-CE 4.34Å; L651-M685 HydrophobicContact CD2-CB 4.18Å; L651-M685 HydrophobicContact CD2-CE 3.87Å; L651-M685 HydrophobicContact CD2-SD 4.08Å; L651-I686 HydrophobicContact CB-CD1 4.15Å; L651-I686 HydrophobicContact CB-CG1 3.58Å; L651-I686 HydrophobicContact CD1-CG1 4.32Å
652Q98Very high94.9Very high61 Ų6155.1 Ų55.129%0.28526%0.258SS..Hα-helixtrans-62.8-41174.1-171.46455.200111.4R648 I649 E650 C654 H655 D656R648-Q652 WeakPolarHBondContact O-CB 3.23Å; R648-Q652 PolarHBondContact O-N 3.3Å; I649-Q652 PolarHBondContact O-N 3.31Å; E650-Q652 VanDerWaalsContact C-N 3.32Å; E650-Q652 PolarHBondContact O-N 3.22Å; Q652-C654 VanDerWaalsContact C-N 3.33Å; Q652-C654 PolarHBondContact O-N 3.34Å; Q652-H655 WeakPolarHBondContact O-CB 3.5Å; Q652-H655 PolarHBondContact O-N 2.81Å; Q652-D656 PolarHBondContact NE2-OD1 2.85Å; Q652-D656 PolarHBondContact O-N 3.47Å
653R97.7Very high94.7Very high132 Ų13261 Ų6150%0.49828%0.279SS..Hα-helixtrans-61.9-41.2174.3-68.6170.4179173.9-4.8111.9I649 E650 L651 D656 R657I649-R653 WeakPolarHBondContact O-CG 3.3Å; I649-R653 PolarHBondContact O-N 2.95Å; I649-R653 VanDerWaalsContact O-N 3.11Å; E650-R653 WeakPolarHBondContact O-CB 3.45Å; E650-R653 PolarHBondContact O-N 3.29Å; E650-R653 WeakPolarHBondContact OE2-CD 3.41Å; E650-R653 IonicContact OE2-CZ 3.32Å; E650-R653 IonicContact OE2-NE 3.36Å; E650-R653 IonicContact OE2-NH1 3.8Å; E650-R653 PolarHBondContact OE2-NH1 2.85Å; L651-R653 VanDerWaalsContact C-N 3.33Å; L651-R653 PolarHBondContact O-N 3.1Å; R653-D656 PolarHBondContact O-N 3.38Å; R653-R657 WeakPolarHBondContact O-CB 3.2Å; R653-R657 VanDerWaalsContact O-CG 3.28Å; R653-R657 WeakPolarHBondContact O-CG 3.38Å; R653-R657 PolarHBondContact O-N 3.32Å
654C96.7Very high94.1Very high1 Ų161.5 Ų61.51%0.00730%0.297CS..Hα-helixtrans-58.7-47.1173.5-72.20000111.4T586 E650 L651 Q652 R657 L658 I682T586-C654 HydrophobicContact CG2-CB 3.65Å; E650-C654 PolarHBondContact O-N 2.92Å; E650-C654 PolarHBondContact O-SG 2.87Å; L651-C654 WeakPolarHBondContact O-CB 3.45Å; L651-C654 PolarHBondContact O-N 3.48Å; Q652-C654 VanDerWaalsContact C-N 3.33Å; Q652-C654 PolarHBondContact O-N 3.34Å; C654-R657 PolarHBondContact O-N 2.96Å; C654-L658 PolarHBondContact O-N 3.4Å; C654-L658 VanDerWaalsContact O-N 3.17Å; C654-I682 HydrophobicContact CB-CD1 4.23Å
655H97.1Very high93.2Very high26 Ų2663.1 Ų63.112%0.1231%0.305CS..Hα-helixtrans-59.5-49.4176.5-175.2-79.1000112L651 Q652 R657 L658 E659 I682 D683L651-H655 PolarHBondContact O-N 2.85Å; Q652-H655 WeakPolarHBondContact O-CB 3.5Å; Q652-H655 PolarHBondContact O-N 2.81Å; H655-R657 VanDerWaalsContact C-N 3.32Å; H655-R657 PolarHBondContact O-N 2.98Å; H655-L658 PolarHBondContact O-N 2.95Å; H655-E659 PolarHBondContact O-N 3.11Å; H655-I682 HydrophobicContact CB-CG2 3.88Å; H655-D683 IonicContact CD2-OD1 3.57Å; H655-D683 IonicContact NE2-OD1 2.73Å; H655-D683 IonicContact NE2-OD2 3.57Å
656D96.4Very high92Very high79 Ų7964.2 Ų64.242%0.42232%0.318SS..Hα-helixtrans-64.2-37.5-177.7-62.4-17.2000111.8Q652 R653 E659 V660Q652-D656 PolarHBondContact NE2-OD1 2.85Å; Q652-D656 PolarHBondContact O-N 3.47Å; R653-D656 PolarHBondContact O-N 3.38Å; D656-E659 PolarHBondContact O-N 2.86Å; D656-V660 WeakPolarHBondContact O-CG2 3.19Å; D656-V660 PolarHBondContact O-N 3.05Å
657R93.6Very high91Very high96 Ų9668.3 Ų68.336%0.36233%0.331SS..Hα-helixtrans-60.7-45.3173.8-79.2178.3-178.4179.44.3112.2I582 R653 C654 H655 E659 V660 A661I582-R657 HydrophobicContact CD1-CB 4.2Å; I582-R657 HydrophobicContact CG1-CB 4.47Å; R653-R657 WeakPolarHBondContact O-CB 3.2Å; R653-R657 VanDerWaalsContact O-CG 3.28Å; R653-R657 WeakPolarHBondContact O-CG 3.38Å; R653-R657 PolarHBondContact O-N 3.32Å; C654-R657 PolarHBondContact O-N 2.96Å; H655-R657 VanDerWaalsContact C-N 3.32Å; H655-R657 PolarHBondContact O-N 2.98Å; R657-E659 VanDerWaalsContact C-N 3.34Å; R657-V660 PolarHBondContact O-N 2.74Å; R657-A661 WeakPolarHBondContact O-CB 3.36Å; R657-A661 PolarHBondContact O-N 3.45Å
658L93.7Very high90.3Very high0 Ų070.9 Ų70.90%034%0.344CS..Hα-helixtrans-64.3-39.1176.2-72.4177.1000112.1L583 T586 C654 H655 A661 K662 V678 Q679 I682L583-L658 HydrophobicContact CB-CD2 4.43Å; L583-L658 HydrophobicContact CD1-CD2 3.86Å; T586-L658 HydrophobicContact CG2-CD1 3.74Å; T586-L658 HydrophobicContact CG2-CD2 4.35Å; T586-L658 HydrophobicContact CG2-CG 3.91Å; C654-L658 PolarHBondContact O-N 3.4Å; C654-L658 VanDerWaalsContact O-N 3.17Å; H655-L658 PolarHBondContact O-N 2.95Å; L658-A661 PolarHBondContact O-N 3.32Å; L658-K662 VanDerWaalsContact O-CB 3.27Å; L658-K662 WeakPolarHBondContact O-CB 3.26Å; L658-K662 PolarHBondContact O-N 3.2Å; L658-V678 HydrophobicContact CD1-CB 4.46Å; L658-V678 HydrophobicContact CD1-CG1 3.84Å; L658-Q679 HydrophobicContact CB-CG 4.33Å; L658-Q679 HydrophobicContact CD1-CG 4.02Å; L658-I682 HydrophobicContact CD1-CD1 3.55Å
659E93Very high89.9Confident54 Ų5473.5 Ų73.525%0.25236%0.355SS..Hα-helixtrans-63.9-39.9176.6-83.7-62.8130.300112.8H655 D656 R657 K662 K663 Q679H655-E659 PolarHBondContact O-N 3.11Å; D656-E659 PolarHBondContact O-N 2.86Å; R657-E659 VanDerWaalsContact C-N 3.34Å; E659-K662 IonicContact OE1-NZ 2.7Å; E659-K663 WeakPolarHBondContact O-CG 3.29Å; E659-K663 PolarHBondContact O-N 2.91Å; E659-Q679 PolarHBondContact OE1-NE2 3.07Å; E659-Q679 PolarHBondContact OE1-OE1 3.03Å
660V91.3Very high89.4Confident103 Ų10371.7 Ų71.762%0.62435%0.345SS*.Hα-helixtrans-65-46.5173.5172.80000110.6D656 R657 K662 K663D656-V660 WeakPolarHBondContact O-CG2 3.19Å; D656-V660 PolarHBondContact O-N 3.05Å; R657-V660 PolarHBondContact O-N 2.74Å; V660-K662 VanDerWaalsContact C-N 3.31Å; V660-K662 PolarHBondContact O-N 3.42Å; V660-K663 PolarHBondContact O-N 3.47Å
661A87.5Confident89Confident16 Ų1669.6 Ų69.613%0.13234%0.335CS..Hα-helixtrans-57.7-45.6177.700000111.3I582 R657 L658 K663 A664 M665I582-A661 HydrophobicContact CB-CB 4.45Å; I582-A661 HydrophobicContact CG1-CB 4.23Å; I582-A661 HydrophobicContact CG2-CB 3.45Å; I582-A661 VanDerWaalsContact CG2-CB 3.45Å; R657-A661 WeakPolarHBondContact O-CB 3.36Å; R657-A661 PolarHBondContact O-N 3.45Å; L658-A661 PolarHBondContact O-N 3.32Å; A661-K663 PolarHBondContact O-N 3.04Å; A661-A664 WeakPolarHBondContact O-CA 3.27Å; A661-A664 WeakPolarHBondContact O-CB 3.37Å; A661-A664 PolarHBondContact O-N 3.33Å; A661-M665 HydrophobicContact CB-CE 3.72Å; A661-M665 WeakPolarHBondContact O-CG 3.3Å; A661-M665 PolarHBondContact O-N 3.04Å
662K87.9Confident88.6Confident83 Ų8371.7 Ų71.736%0.36135%0.352SS..Hα-helixtrans-56.7-36-178.6-174.3179.6178.1179.80113.2L658 E659 V660 A664 M665 V675L658-K662 VanDerWaalsContact O-CB 3.27Å; L658-K662 WeakPolarHBondContact O-CB 3.26Å; L658-K662 PolarHBondContact O-N 3.2Å; E659-K662 IonicContact OE1-NZ 2.7Å; V660-K662 VanDerWaalsContact C-N 3.31Å; V660-K662 PolarHBondContact O-N 3.42Å; K662-A664 VanDerWaalsContact C-N 3.31Å; K662-M665 HydrophobicContact CB-CE 4.14Å; K662-M665 VanDerWaalsContact N-CE 3.29Å; K662-V675 HydrophobicContact CB-CG1 4.43Å; K662-V675 HydrophobicContact CD-CG1 4.18Å; K662-V675 HydrophobicContact CG-CG1 4.49Å
663K87.4Confident88.4Confident173 Ų17369.4 Ų69.475%0.75234%0.342SS*.Hα-helixtrans-72.4-23.8177.1-68.1172-175.1175.60113.3E659 V660 A661E659-K663 WeakPolarHBondContact O-CG 3.29Å; E659-K663 PolarHBondContact O-N 2.91Å; V660-K663 PolarHBondContact O-N 3.47Å; A661-K663 PolarHBondContact O-N 3.04Å
664A80.5Confident88.2Confident75 Ų7563.3 Ų63.362%0.6232%0.319SS*.Hα-helixtrans-89.8-11.1179.500000113.4A661 K662A661-A664 WeakPolarHBondContact O-CA 3.27Å; A661-A664 WeakPolarHBondContact O-CB 3.37Å; A661-A664 PolarHBondContact O-N 3.33Å; K662-A664 VanDerWaalsContact C-N 3.31Å
665M76.4Confident88.1Confident34 Ų3463.2 Ų63.217%0.16732%0.319CS..SBendtrans-76.8144.9-172.7-48-177.9-174.100112.4M580 A661 K662 L671 V675M580-M665 HydrophobicContact CE-CE 3.17Å; M580-M665 HydrophobicContact CE-SD 3.66Å; M580-M665 HydrophobicContact SD-CE 3.16Å; M580-M665 WeakPolarHBondContact SD-CE 3.36Å; M580-M665 HydrophobicContact SD-CG 3.86Å; M580-M665 HydrophobicContact SD-SD 3.37Å; A661-M665 HydrophobicContact CB-CE 3.72Å; A661-M665 WeakPolarHBondContact O-CG 3.3Å; A661-M665 PolarHBondContact O-N 3.04Å; K662-M665 HydrophobicContact CB-CE 4.14Å; K662-M665 VanDerWaalsContact N-CE 3.29Å; M665-L671 HydrophobicContact SD-CD2 3.85Å; M665-L671 HydrophobicContact SD-CG 3.99Å; M665-V675 HydrophobicContact CE-CG2 3.71Å; M665-V675 HydrophobicContact SD-CG2 4.12Å
666P71.4Confident87.9Confident92 Ų9263.4 Ų63.460%0.59733%0.325SS*.  trans-64.4149.1162.628.8-33.3000110.4N668P666-N668 PolarHBondContact O-N 3.2Å
667Y73.7Confident87.9Confident218 Ų21860.2 Ų60.286%0.85531%0.308SS*.  trans-60.8110.3179.8-178-94.3000110.9
668N83.7Confident88Confident64 Ų6455.6 Ų55.634%0.34229%0.29SS..  trans-141.3113.6172.9180-15.4000108.1P666 E670 L671 A672P666-N668 PolarHBondContact O-N 3.2Å; N668-E670 PolarHBondContact O-N 2.75Å; N668-E670 PolarHBondContact OD1-N 3.36Å; N668-E670 VanDerWaalsContact OD1-N 3.16Å; N668-L671 HydrophobicContact CB-CB 3.91Å; N668-L671 PolarHBondContact O-N 3.42Å; N668-L671 PolarHBondContact OD1-N 3.15Å; N668-A672 WeakPolarHBondContact O-CB 3.1Å; N668-A672 PolarHBondContact O-N 3.07Å
669Y87.8Confident88.2Confident116 Ų11655.9 Ų55.946%0.45529%0.292SS..Hα-helixtrans-57.6-46.6-176.5173.9-98.1000112.5L671 A672 L673 S743Y669-L671 VanDerWaalsContact C-N 3.33Å; Y669-L671 PolarHBondContact O-N 3.34Å; Y669-A672 PolarHBondContact O-N 3.14Å; Y669-L673 HydrophobicContact CE1-CD2 4.29Å; Y669-L673 WeakPolarHBondContact O-CB 3.3Å; Y669-L673 PolarHBondContact O-N 3.08Å; Y669-S743 PolarHBondContact OH-OG 3.11Å
670E87.5Confident88.4Confident30 Ų3053.7 Ų53.714%0.1428%0.281CS..Hα-helixtrans-62.3-43.5-179.1-75.6-64.313400111.5Q328 R332 N668 L673 C674 R744Q328-E670 PolarHBondContact NE2-OE1 3.17Å; Q328-E670 PolarHBondContact OE1-OE1 3.28Å; Q328-E670 PolarHBondContact OE1-OE2 3.39Å; R332-E670 IonicContact CZ-OE2 3.75Å; R332-E670 IonicContact NH1-OE2 3.95Å; R332-E670 IonicContact NH2-OE2 3.36Å; R332-E670 PolarHBondContact NH2-OE2 3.13Å; N668-E670 PolarHBondContact O-N 2.75Å; N668-E670 PolarHBondContact OD1-N 3.36Å; N668-E670 VanDerWaalsContact OD1-N 3.16Å; E670-L673 PolarHBondContact O-N 3.01Å; E670-C674 PolarHBondContact O-N 3.39Å; E670-C674 PolarHBondContact O-SG 3.29Å; E670-R744 IonicContact OE1-NH1 3.66Å; E670-R744 IonicContact OE2-CZ 3.96Å; E670-R744 VanDerWaalsContact OE2-CZ 3.25Å; E670-R744 IonicContact OE2-NH1 2.75Å; E670-R744 PolarHBondContact OE2-NH1 2.92Å; E670-R744 IonicContact OE2-NH2 3.61Å; E670-R744 PolarHBondContact OE2-NH2 2.82Å
671L89Confident88.6Confident9 Ų948.8 Ų48.85%0.04725%0.252CS..Hα-helixtrans-65.7-44178.6-175.157.7000111.7T575 M580 M665 N668 Y669 L673 C674 V675T575-L671 HydrophobicContact CG2-CD1 3.74Å; M580-L671 HydrophobicContact CE-CD1 3.44Å; M580-L671 VanDerWaalsContact CE-CD1 3.44Å; M580-L671 HydrophobicContact CE-CD2 4.17Å; M580-L671 HydrophobicContact CE-CG 3.95Å; M580-L671 HydrophobicContact CG-CD1 3.95Å; M580-L671 HydrophobicContact CG-CD2 3.68Å; M580-L671 HydrophobicContact CG-CG 4.35Å; M580-L671 HydrophobicContact SD-CD1 4.19Å; M580-L671 HydrophobicContact SD-CD2 3.86Å; M580-L671 HydrophobicContact SD-CG 4.31Å; M665-L671 HydrophobicContact SD-CD2 3.85Å; M665-L671 HydrophobicContact SD-CG 3.99Å; N668-L671 HydrophobicContact CB-CB 3.91Å; N668-L671 PolarHBondContact O-N 3.42Å; N668-L671 PolarHBondContact OD1-N 3.15Å; Y669-L671 VanDerWaalsContact C-N 3.33Å; Y669-L671 PolarHBondContact O-N 3.34Å; L671-L673 VanDerWaalsContact C-N 3.25Å; L671-L673 PolarHBondContact O-N 2.79Å; L671-C674 PolarHBondContact O-N 3.1Å; L671-V675 WeakPolarHBondContact O-CG2 3.47Å; L671-V675 PolarHBondContact O-N 3.42Å
672A91.1Very high89.1Confident43 Ų4348 Ų4836%0.35525%0.245SC..Hα-helixtrans-60.4-38176.500000111.7N668 Y669 A676N668-A672 WeakPolarHBondContact O-CB 3.1Å; N668-A672 PolarHBondContact O-N 3.07Å; Y669-A672 PolarHBondContact O-N 3.14Å; A672-A676 WeakPolarHBondContact O-CB 3.37Å; A672-A676 PolarHBondContact O-N 3.48Å
673L93.2Very high89.5Confident13 Ų1344.2 Ų44.27%0.06823%0.229CC..Hα-helixtrans-66.2-47.2175.1-17858.5000111.7Y669 E670 L671 V675 A676 E677 A740 R744Y669-L673 HydrophobicContact CE1-CD2 4.29Å; Y669-L673 WeakPolarHBondContact O-CB 3.3Å; Y669-L673 PolarHBondContact O-N 3.08Å; E670-L673 PolarHBondContact O-N 3.01Å; L671-L673 VanDerWaalsContact C-N 3.25Å; L671-L673 PolarHBondContact O-N 2.79Å; L673-V675 VanDerWaalsContact C-N 3.3Å; L673-V675 PolarHBondContact O-N 3.37Å; L673-A676 PolarHBondContact O-N 2.98Å; L673-A676 VanDerWaalsContact O-N 3.16Å; L673-E677 HydrophobicContact CD1-CG 4.36Å; L673-E677 WeakPolarHBondContact O-CB 3.42Å; L673-E677 WeakPolarHBondContact O-CG 3.43Å; L673-E677 PolarHBondContact O-N 3.29Å; L673-A740 HydrophobicContact CD1-CB 4.32Å; L673-R744 HydrophobicContact CD2-CG 4.16Å
674C93.1Very high89.9Confident4 Ų436 Ų363%0.02719%0.193CC..Hα-helixtrans-58.4-41.2176.1-63.40000112.2S539 L583 E670 L671 E677 V678S539-C674 WeakPolarHBondContact OG-CB 3.34Å; S539-C674 PolarHBondContact OG-SG 3.49Å; S539-C674 VanDerWaalsContact OG-SG 3.34Å; L583-C674 HydrophobicContact CD2-CB 4.29Å; E670-C674 PolarHBondContact O-N 3.39Å; E670-C674 PolarHBondContact O-SG 3.29Å; L671-C674 PolarHBondContact O-N 3.1Å; C674-E677 PolarHBondContact O-N 3.46Å; C674-V678 WeakPolarHBondContact O-CG2 3.44Å; C674-V678 PolarHBondContact O-N 3.2Å; C674-V678 VanDerWaalsContact O-N 3.08Å
675V94.2Very high90.7Very high0 Ų032.5 Ų32.50%016%0.164CC..Hα-helixtrans-64.6-45.4176.3173.50000110.8M580 L583 K662 M665 L671 L673 E677 V678 Q679M580-V675 HydrophobicContact CE-CG2 3.75Å; L583-V675 HydrophobicContact CD1-CG2 4.28Å; K662-V675 HydrophobicContact CB-CG1 4.43Å; K662-V675 HydrophobicContact CD-CG1 4.18Å; K662-V675 HydrophobicContact CG-CG1 4.49Å; M665-V675 HydrophobicContact CE-CG2 3.71Å; M665-V675 HydrophobicContact SD-CG2 4.12Å; L671-V675 WeakPolarHBondContact O-CG2 3.47Å; L671-V675 PolarHBondContact O-N 3.42Å; L673-V675 VanDerWaalsContact C-N 3.3Å; L673-V675 PolarHBondContact O-N 3.37Å; V675-E677 VanDerWaalsContact C-N 3.34Å; V675-E677 PolarHBondContact O-N 3.19Å; V675-V678 PolarHBondContact O-N 3.4Å; V675-Q679 HydrophobicContact CG1-CG 4.32Å; V675-Q679 WeakPolarHBondContact O-CB 3.47Å; V675-Q679 VanDerWaalsContact O-CG 3.23Å; V675-Q679 WeakPolarHBondContact O-CG 3.36Å; V675-Q679 PolarHBondContact O-N 3.05Å
676A94.4Very high91.7Very high30 Ų3031.1 Ų31.125%0.24816%0.158CC..Hα-helixtrans-62.3-40.7178.200000112.3A672 L673 Q679 L680A672-A676 WeakPolarHBondContact O-CB 3.37Å; A672-A676 PolarHBondContact O-N 3.48Å; L673-A676 PolarHBondContact O-N 2.98Å; L673-A676 VanDerWaalsContact O-N 3.16Å; A676-Q679 PolarHBondContact O-N 2.78Å; A676-L680 WeakPolarHBondContact O-CG 3.5Å; A676-L680 PolarHBondContact O-N 3.02Å
677E95.5Very high92.9Very high11 Ų1127 Ų275%0.05113%0.131CC..Hα-helixtrans-59.4-47.7174.7-77.9173.9-177.500112P537 S539 L673 C674 V675 L680 V681 A740 R744P537-E677 HydrophobicContact CB-CB 3.67Å; P537-E677 HydrophobicContact CB-CG 3.85Å; P537-E677 HydrophobicContact CG-CB 3.83Å; S539-E677 WeakPolarHBondContact CB-OE2 3.37Å; S539-E677 PolarHBondContact OG-OE2 3.28Å; L673-E677 HydrophobicContact CD1-CG 4.36Å; L673-E677 WeakPolarHBondContact O-CB 3.42Å; L673-E677 WeakPolarHBondContact O-CG 3.43Å; L673-E677 PolarHBondContact O-N 3.29Å; C674-E677 PolarHBondContact O-N 3.46Å; V675-E677 VanDerWaalsContact C-N 3.34Å; V675-E677 PolarHBondContact O-N 3.19Å; E677-L680 WeakPolarHBondContact O-CB 3.4Å; E677-L680 PolarHBondContact O-N 2.94Å; E677-V681 PolarHBondContact O-N 3.31Å; E677-A740 HydrophobicContact CG-CB 4.4Å; E677-R744 WeakPolarHBondContact OE1-CG 3.48Å; E677-R744 IonicContact OE1-NE 2.66Å; E677-R744 PolarHBondContact OE1-NE 2.79Å
678V96.4Very high94Very high0 Ų016.7 Ų16.70%09%0.09CC..Hα-helixtrans-67.2-39177.3175.30000111.3L540 L583 I587 L658 C674 V675 L680 V681 I682L540-V678 HydrophobicContact CD2-CG2 4.03Å; L583-V678 HydrophobicContact CD1-CB 4.07Å; L583-V678 HydrophobicContact CD1-CG1 4.31Å; L583-V678 HydrophobicContact CD1-CG2 3.86Å; I587-V678 HydrophobicContact CD1-CG2 4.01Å; I587-V678 HydrophobicContact CG1-CG1 4.11Å; I587-V678 HydrophobicContact CG1-CG2 4.05Å; L658-V678 HydrophobicContact CD1-CB 4.46Å; L658-V678 HydrophobicContact CD1-CG1 3.84Å; C674-V678 WeakPolarHBondContact O-CG2 3.44Å; C674-V678 PolarHBondContact O-N 3.2Å; C674-V678 VanDerWaalsContact O-N 3.08Å; V675-V678 PolarHBondContact O-N 3.4Å; V678-L680 VanDerWaalsContact C-N 3.31Å; V678-L680 PolarHBondContact O-N 3.34Å; V678-V681 PolarHBondContact O-N 3.44Å; V678-I682 HydrophobicContact CG1-CD1 4Å; V678-I682 HydrophobicContact CG1-CG1 4.49Å; V678-I682 WeakPolarHBondContact O-CG1 3.36Å; V678-I682 PolarHBondContact O-N 2.97Å
679Q96.7Very high94.5Very high6 Ų613.7 Ų13.73%0.0287%0.074CC..Hα-helixtrans-61.3-38.5175.4-75.1177-34.600112.6L658 E659 V675 A676 V681 I682 D683L658-Q679 HydrophobicContact CB-CG 4.33Å; L658-Q679 HydrophobicContact CD1-CG 4.02Å; E659-Q679 PolarHBondContact OE1-NE2 3.07Å; E659-Q679 PolarHBondContact OE1-OE1 3.03Å; V675-Q679 HydrophobicContact CG1-CG 4.32Å; V675-Q679 WeakPolarHBondContact O-CB 3.47Å; V675-Q679 VanDerWaalsContact O-CG 3.23Å; V675-Q679 WeakPolarHBondContact O-CG 3.36Å; V675-Q679 PolarHBondContact O-N 3.05Å; A676-Q679 PolarHBondContact O-N 2.78Å; Q679-V681 VanDerWaalsContact C-N 3.34Å; Q679-V681 PolarHBondContact O-N 2.67Å; Q679-I682 PolarHBondContact O-N 3.44Å; Q679-D683 WeakPolarHBondContact O-CB 3.44Å; Q679-D683 PolarHBondContact O-N 2.99Å
680L96.7Very high94.9Very high7 Ų712.4 Ų12.44%0.0377%0.068CC..Hα-helixtrans-59-44.4174.6-79166.8000112A676 E677 V678 D683 M684 I733 R736 F737 A740A676-L680 WeakPolarHBondContact O-CG 3.5Å; A676-L680 PolarHBondContact O-N 3.02Å; E677-L680 WeakPolarHBondContact O-CB 3.4Å; E677-L680 PolarHBondContact O-N 2.94Å; V678-L680 VanDerWaalsContact C-N 3.31Å; V678-L680 PolarHBondContact O-N 3.34Å; L680-D683 PolarHBondContact O-N 3.45Å; L680-M684 WeakPolarHBondContact O-CB 3.5Å; L680-M684 PolarHBondContact O-N 3.41Å; L680-I733 HydrophobicContact CD2-CG2 3.94Å; L680-R736 HydrophobicContact CD2-CB 3.62Å; L680-F737 HydrophobicContact CD1-CB 4.4Å; L680-F737 HydrophobicContact CD2-CB 4.29Å; L680-A740 HydrophobicContact CD1-CB 3.68Å
681V96.6Very high95.2Very high0 Ų011.1 Ų11.10%06%0.063CC..Hα-helixtrans-64.8-45.2177.3-179.70000110.7F498 I535 P537 L540 M590 E677 V678 Q679 D683 M684 M685F498-V681 HydrophobicContact CB-CG1 4.34Å; F498-V681 HydrophobicContact CD2-CG1 3.99Å; F498-V681 HydrophobicContact CG-CG1 4.25Å; I535-V681 HydrophobicContact CG1-CG2 4.4Å; P537-V681 HydrophobicContact CG-CG2 4.23Å; L540-V681 HydrophobicContact CD1-CG1 4.36Å; L540-V681 HydrophobicContact CD1-CG2 4.2Å; M590-V681 HydrophobicContact CE-CG1 3.94Å; M590-V681 HydrophobicContact SD-CB 4.27Å; M590-V681 HydrophobicContact SD-CG1 3.77Å; E677-V681 PolarHBondContact O-N 3.31Å; V678-V681 PolarHBondContact O-N 3.44Å; Q679-V681 VanDerWaalsContact C-N 3.34Å; Q679-V681 PolarHBondContact O-N 2.67Å; V681-D683 PolarHBondContact O-N 2.78Å; V681-M684 PolarHBondContact O-N 2.89Å; V681-M685 HydrophobicContact CG1-CG 4.47Å; V681-M685 HydrophobicContact CG1-SD 4.14Å; V681-M685 WeakPolarHBondContact O-CG 3.37Å; V681-M685 PolarHBondContact O-N 3.37Å
682I97.6Very high95.3Very high0 Ų010.7 Ų10.70%06%0.06CC..Hα-helixtrans-59.9-46.2177.1-66.4167.3000111T586 M590 L651 C654 H655 L658 V678 Q679 M684 M685 I686T586-I682 HydrophobicContact CG2-CD1 3.76Å; M590-I682 HydrophobicContact SD-CG1 3.63Å; L651-I682 HydrophobicContact CB-CG2 4.27Å; L651-I682 HydrophobicContact CD2-CG2 4.4Å; L651-I682 WeakPolarHBondContact O-CG2 3.21Å; C654-I682 HydrophobicContact CB-CD1 4.23Å; H655-I682 HydrophobicContact CB-CG2 3.88Å; L658-I682 HydrophobicContact CD1-CD1 3.55Å; V678-I682 HydrophobicContact CG1-CD1 4Å; V678-I682 HydrophobicContact CG1-CG1 4.49Å; V678-I682 WeakPolarHBondContact O-CG1 3.36Å; V678-I682 PolarHBondContact O-N 2.97Å; Q679-I682 PolarHBondContact O-N 3.44Å; I682-M684 VanDerWaalsContact C-N 3.28Å; I682-M684 PolarHBondContact O-N 2.91Å; I682-M685 PolarHBondContact O-N 3.49Å; I682-I686 HydrophobicContact CG2-CD1 3.81Å; I682-I686 HydrophobicContact CG2-CG1 4.34Å; I682-I686 VanDerWaalsContact O-CG1 3.29Å; I682-I686 WeakPolarHBondContact O-CG1 3.33Å; I682-I686 PolarHBondContact O-N 3.28Å
683D97.4Very high95.4Very high4 Ų49.6 Ų9.62%0.0215%0.048CC..Hα-helixtrans-60.6-40178-84.3-43000112.2H655 Q679 L680 V681 I686 L687 R729 I733 R736H655-D683 IonicContact CD2-OD1 3.57Å; H655-D683 IonicContact NE2-OD1 2.73Å; H655-D683 IonicContact NE2-OD2 3.57Å; Q679-D683 WeakPolarHBondContact O-CB 3.44Å; Q679-D683 PolarHBondContact O-N 2.99Å; L680-D683 PolarHBondContact O-N 3.45Å; V681-D683 PolarHBondContact O-N 2.78Å; D683-I686 PolarHBondContact O-N 2.79Å; D683-L687 PolarHBondContact O-N 3.05Å; D683-R729 IonicContact OD1-CZ 3.56Å; D683-R729 IonicContact OD1-NH2 3.87Å; D683-R729 PolarHBondContact OD1-NH2 2.82Å; D683-R729 IonicContact OD2-NH2 3.86Å; D683-I733 HydrophobicContact CB-CD1 3.89Å; D683-I733 HydrophobicContact CB-CG1 4.02Å; D683-R736 IonicContact OD2-CZ 3.35Å; D683-R736 IonicContact OD2-NH1 2.85Å; D683-R736 PolarHBondContact OD2-NH1 2.83Å; D683-R736 IonicContact OD2-NH2 3.41Å; D683-R736 PolarHBondContact OD2-NH2 2.87Å
684M95.9Very high95.3Very high0 Ų09.4 Ų9.40%05%0.048CC..Hα-helixtrans-69.3-37.7177.2-166.258.7153.600111.9I535 L615 L680 V681 I682 L687 G688 L730 F757 L760I535-M684 HydrophobicContact CD1-CB 3.34Å; I535-M684 HydrophobicContact CD1-CG 3.51Å; L615-M684 HydrophobicContact CB-CE 4.5Å; L615-M684 HydrophobicContact CD1-CE 3.92Å; L615-M684 HydrophobicContact CD1-CG 3.38Å; L615-M684 HydrophobicContact CD1-SD 4.35Å; L615-M684 HydrophobicContact CD2-CE 3.58Å; L615-M684 HydrophobicContact CD2-CG 3.67Å; L615-M684 HydrophobicContact CD2-SD 3.75Å; L615-M684 HydrophobicContact CG-CE 4.15Å; L615-M684 HydrophobicContact CG-CG 4.13Å; L680-M684 WeakPolarHBondContact O-CB 3.5Å; L680-M684 PolarHBondContact O-N 3.41Å; V681-M684 PolarHBondContact O-N 2.89Å; I682-M684 VanDerWaalsContact C-N 3.28Å; I682-M684 PolarHBondContact O-N 2.91Å; M684-L687 WeakPolarHBondContact O-CB 3.4Å; M684-L687 PolarHBondContact O-N 3.17Å; M684-L687 HydrophobicContact SD-CD2 3.89Å; M684-G688 PolarHBondContact O-N 3.37Å; M684-L730 HydrophobicContact CE-CD1 3.85Å; M684-L730 HydrophobicContact SD-CD1 4.1Å; M684-F757 HydrophobicContact CE-CD1 4.13Å; M684-F757 HydrophobicContact CE-CE1 3.85Å; M684-F757 HydrophobicContact CE-CZ 4.45Å; M684-F757 HydrophobicContact SD-CE1 4.39Å; M684-L760 HydrophobicContact CE-CD2 4.01Å
685M96.8Very high95.1Very high1 Ų19.3 Ų9.31%0.0055%0.047CC..Hα-helixtrans-66.2-38.2171.2-68.3174.374.300111.9F498 M590 E594 F611 L651 V681 I682 G688 A689F498-M685 HydrophobicContact CD2-CG 3.98Å; F498-M685 HydrophobicContact CD2-SD 3.99Å; F498-M685 HydrophobicContact CE2-CG 3.75Å; F498-M685 HydrophobicContact CE2-SD 4.37Å; M590-M685 HydrophobicContact CG-CE 3.91Å; M590-M685 HydrophobicContact CG-SD 3.39Å; M590-M685 WeakPolarHBondContact CG-SD 3.39Å; M590-M685 HydrophobicContact SD-SD 3.75Å; E594-M685 HydrophobicContact CB-CE 3.82Å; F611-M685 HydrophobicContact CD1-CB 4.08Å; F611-M685 HydrophobicContact CD1-CG 4.23Å; F611-M685 HydrophobicContact CD2-CE 3.62Å; F611-M685 HydrophobicContact CD2-CG 4.43Å; F611-M685 HydrophobicContact CE1-CB 4Å; F611-M685 WeakPolarHBondContact CE1-O 3.13Å; F611-M685 HydrophobicContact CE2-CE 3.45Å; F611-M685 VanDerWaalsContact CE2-CE 3.45Å; F611-M685 HydrophobicContact CG-CB 4.49Å; F611-M685 HydrophobicContact CG-CE 4.29Å; F611-M685 HydrophobicContact CG-CG 4.17Å; F611-M685 HydrophobicContact CZ-CB 4.31Å; F611-M685 HydrophobicContact CZ-CE 4.03Å; L651-M685 HydrophobicContact CD1-CB 3.59Å; L651-M685 HydrophobicContact CD1-CE 4.34Å; L651-M685 HydrophobicContact CD2-CB 4.18Å; L651-M685 HydrophobicContact CD2-CE 3.87Å; L651-M685 HydrophobicContact CD2-SD 4.08Å; V681-M685 HydrophobicContact CG1-CG 4.47Å; V681-M685 HydrophobicContact CG1-SD 4.14Å; V681-M685 WeakPolarHBondContact O-CG 3.37Å; V681-M685 PolarHBondContact O-N 3.37Å; I682-M685 PolarHBondContact O-N 3.49Å; M685-G688 PolarHBondContact O-N 3.11Å; M685-A689 WeakPolarHBondContact O-CB 3.45Å; M685-A689 PolarHBondContact O-N 3.38Å
686I97.7Very high94.7Very high6 Ų69.4 Ų9.43%0.0315%0.048CC..Hα-helixtrans-62.1-44.8174.1-71.8168.3000110.3R648 L651 I682 D683 A689 R690R648-I686 HydrophobicContact CG-CG2 4.23Å; L651-I686 HydrophobicContact CB-CD1 4.15Å; L651-I686 HydrophobicContact CB-CG1 3.58Å; L651-I686 HydrophobicContact CD1-CG1 4.32Å; I682-I686 HydrophobicContact CG2-CD1 3.81Å; I682-I686 HydrophobicContact CG2-CG1 4.34Å; I682-I686 VanDerWaalsContact O-CG1 3.29Å; I682-I686 WeakPolarHBondContact O-CG1 3.33Å; I682-I686 PolarHBondContact O-N 3.28Å; D683-I686 PolarHBondContact O-N 2.79Å; I686-A689 PolarHBondContact O-N 2.85Å; I686-R690 WeakPolarHBondContact O-CG 3.48Å; I686-R690 PolarHBondContact O-N 2.8Å
687L96.5Very high94.2Very high6 Ų612.7 Ų12.73%0.0316%0.061CC..Hα-helixtrans-59.1-48.9174.3-172.982.5000110.6D683 M684 A689 R690 L691 L726 R729 L730 I733 L760D683-L687 PolarHBondContact O-N 3.05Å; M684-L687 WeakPolarHBondContact O-CB 3.4Å; M684-L687 PolarHBondContact O-N 3.17Å; M684-L687 HydrophobicContact SD-CD2 3.89Å; L687-A689 VanDerWaalsContact C-N 3.31Å; L687-A689 PolarHBondContact O-N 3.39Å; L687-R690 WeakPolarHBondContact O-CB 3.39Å; L687-R690 PolarHBondContact O-N 3.49Å; L687-R690 VanDerWaalsContact O-N 3.15Å; L687-L691 PolarHBondContact O-N 3.17Å; L687-L726 HydrophobicContact CD1-CB 4.34Å; L687-L726 HydrophobicContact CD1-CD2 3.66Å; L687-L726 HydrophobicContact CG-CD2 4.34Å; L687-R729 HydrophobicContact CD1-CB 3.92Å; L687-R729 HydrophobicContact CD1-CG 3.95Å; L687-L730 HydrophobicContact CD2-CB 4.08Å; L687-L730 HydrophobicContact CD2-CD1 3.74Å; L687-L730 HydrophobicContact CD2-CG 4.45Å; L687-I733 HydrophobicContact CB-CD1 4.39Å; L687-L760 HydrophobicContact CD2-CD2 4.29Å
688G95.2Very high93.3Very high1 Ų114 Ų141%0.017%0.069CC..Hα-helixtrans-58.7-40.8176.600000112.6M684 M685 L691 G692M684-G688 PolarHBondContact O-N 3.37Å; M685-G688 PolarHBondContact O-N 3.11Å; G688-L691 PolarHBondContact O-N 3.11Å; G688-G692 PolarHBondContact O-N 2.82Å
689A95.9Very high91.9Very high0 Ų014 Ų140%07%0.069CC..Hα-helixtrans-67.6-36.1176.500000112.8F611 F644 R648 M685 I686 L687 Q693F611-A689 HydrophobicContact CE1-CB 4.06Å; F644-A689 HydrophobicContact CD1-CB 4.38Å; R648-A689 HydrophobicContact CB-CB 3.89Å; R648-A689 HydrophobicContact CG-CB 4.49Å; M685-A689 WeakPolarHBondContact O-CB 3.45Å; M685-A689 PolarHBondContact O-N 3.38Å; I686-A689 PolarHBondContact O-N 2.85Å; L687-A689 VanDerWaalsContact C-N 3.31Å; L687-A689 PolarHBondContact O-N 3.39Å; A689-Q693 PolarHBondContact O-N 3.12Å; A689-Q693 PolarHBondContact O-NE2 2.85Å
690R95.7Very high90.1Very high89 Ų8916.5 Ų16.534%0.3369%0.085SC..Hα-helixtrans-66.9-42.8173.2-72.7179.4-176.5-165.53.1111.3R648 I686 L687 Q693 A694 D725 L726R648-R690 VanDerWaalsContact CD-CG 3.48Å; R648-R690 HydrophobicContact CG-CG 4.48Å; I686-R690 WeakPolarHBondContact O-CG 3.48Å; I686-R690 PolarHBondContact O-N 2.8Å; L687-R690 WeakPolarHBondContact O-CB 3.39Å; L687-R690 PolarHBondContact O-N 3.49Å; L687-R690 VanDerWaalsContact O-N 3.15Å; R690-Q693 WeakPolarHBondContact O-CB 3.4Å; R690-Q693 PolarHBondContact O-N 3.43Å; R690-A694 PolarHBondContact O-N 2.67Å; R690-D725 IonicContact NH1-OD2 3.46Å; R690-L726 HydrophobicContact CB-CD2 3.89Å
691L93.6Very high88Confident4 Ų416.6 Ų16.62%0.0219%0.086CC..Hα-helixtrans-63.2-46176.1-179.350.9000110.9I614 P618 L687 G688 Q693 A694 L695 V715 L718 L726 L760I614-L691 HydrophobicContact CG2-CB 4.19Å; I614-L691 HydrophobicContact CG2-CD2 3.7Å; I614-L691 HydrophobicContact CG2-CG 4.06Å; P618-L691 HydrophobicContact CB-CD2 3.78Å; P618-L691 HydrophobicContact CB-CG 4.39Å; P618-L691 HydrophobicContact CG-CD2 4.18Å; L687-L691 PolarHBondContact O-N 3.17Å; G688-L691 PolarHBondContact O-N 3.11Å; L691-Q693 VanDerWaalsContact C-N 3.35Å; L691-Q693 PolarHBondContact O-N 3.01Å; L691-A694 WeakPolarHBondContact O-CB 3.27Å; L691-A694 PolarHBondContact O-N 2.85Å; L691-A694 VanDerWaalsContact O-N 3.1Å; L691-L695 HydrophobicContact CD1-CD1 4.37Å; L691-L695 HydrophobicContact CD1-CG 4.18Å; L691-L695 HydrophobicContact CG-CD1 4.31Å; L691-L695 WeakPolarHBondContact O-CG 3.46Å; L691-L695 PolarHBondContact O-N 2.82Å; L691-V715 HydrophobicContact CD1-CG2 4.2Å; L691-L718 HydrophobicContact CD1-CD1 3.62Å; L691-L726 HydrophobicContact CB-CD1 4.27Å; L691-L726 HydrophobicContact CD1-CD1 3.9Å; L691-L760 HydrophobicContact CD2-CD1 4.21Å
692G92.1Very high85.7Confident0 Ų022.3 Ų22.30%012%0.123CC..Hα-helixtrans-58-41.9173.800000113.5G688 L695 C696G688-G692 PolarHBondContact O-N 2.82Å; G692-L695 PolarHBondContact O-N 2.78Å; G692-C696 PolarHBondContact O-N 3.15Å; G692-C696 PolarHBondContact O-SG 2.83Å
693Q92.1Very high83.4Confident20 Ų2031 Ų319%0.09316%0.155CC..Hα-helixtrans-58-48.3171.1-93156.195.300111.9F641 F644 A689 R690 L691 L695 C696 I697F641-Q693 HydrophobicContact CD2-CB 4.08Å; F641-Q693 HydrophobicContact CD2-CG 3.85Å; F641-Q693 HydrophobicContact CE2-CB 3.93Å; F641-Q693 HydrophobicContact CE2-CG 3.73Å; F641-Q693 HydrophobicContact CZ-CG 4.34Å; F644-Q693 HydrophobicContact CB-CG 3.71Å; F644-Q693 PolarHBondContact O-NE2 3.46Å; A689-Q693 PolarHBondContact O-N 3.12Å; A689-Q693 PolarHBondContact O-NE2 2.85Å; R690-Q693 WeakPolarHBondContact O-CB 3.4Å; R690-Q693 PolarHBondContact O-N 3.43Å; L691-Q693 VanDerWaalsContact C-N 3.35Å; L691-Q693 PolarHBondContact O-N 3.01Å; Q693-L695 PolarHBondContact O-N 3.22Å; Q693-C696 WeakPolarHBondContact O-CB 3.43Å; Q693-C696 PolarHBondContact O-N 2.88Å; Q693-I697 WeakPolarHBondContact O-CG1 3.31Å; Q693-I697 PolarHBondContact O-N 3.36Å; Q693-I697 VanDerWaalsContact O-N 3.07Å
694A91.2Very high81.3Confident9 Ų936.6 Ų36.67%0.07419%0.185CC..Hα-helixtrans-63.6-42-178.700000111.9R690 L691 C696 I697 V698 L718 T722R690-A694 PolarHBondContact O-N 2.67Å; L691-A694 WeakPolarHBondContact O-CB 3.27Å; L691-A694 PolarHBondContact O-N 2.85Å; L691-A694 VanDerWaalsContact O-N 3.1Å; A694-C696 VanDerWaalsContact C-N 3.32Å; A694-C696 PolarHBondContact O-N 3.4Å; A694-I697 PolarHBondContact O-N 3.03Å; A694-I697 VanDerWaalsContact O-N 3.16Å; A694-V698 PolarHBondContact O-N 2.82Å; A694-L718 HydrophobicContact CB-CD1 4.15Å; A694-L718 HydrophobicContact CB-CD2 3.64Å; A694-T722 HydrophobicContact CB-CG2 3.94Å
695L88.2Confident79.2Confident1 Ų143.2 Ų43.21%0.00522%0.221CC..Hα-helixtrans-63.8-37.4175-66.6174.7000111.8P618 L621 L623 L691 G692 Q693 I697 V698 G699 V715 L718P618-L695 HydrophobicContact CB-CD1 4.3Å; L621-L695 HydrophobicContact CD2-CD1 4.01Å; L623-L695 HydrophobicContact CD1-CB 4.13Å; L691-L695 HydrophobicContact CD1-CD1 4.37Å; L691-L695 HydrophobicContact CD1-CG 4.18Å; L691-L695 HydrophobicContact CG-CD1 4.31Å; L691-L695 WeakPolarHBondContact O-CG 3.46Å; L691-L695 PolarHBondContact O-N 2.82Å; G692-L695 PolarHBondContact O-N 2.78Å; Q693-L695 PolarHBondContact O-N 3.22Å; L695-I697 VanDerWaalsContact C-N 3.31Å; L695-I697 PolarHBondContact O-N 3.19Å; L695-V698 PolarHBondContact O-N 2.95Å; L695-G699 PolarHBondContact O-N 3.36Å; L695-V715 HydrophobicContact CD2-CG2 4.31Å; L695-L718 HydrophobicContact CD2-CD2 4.18Å
696C86.2Confident76.9Confident3 Ų347 Ų472%0.0225%0.246CC..Hα-helixtrans-65.1-33.5173.7-670000112.8L637 F641 G692 Q693 A694L637-C696 HydrophobicContact CD1-CB 3.94Å; L637-C696 WeakPolarHBondContact CD2-O 3.39Å; L637-C696 HydrophobicContact CG-CB 4.25Å; L637-C696 WeakPolarHBondContact CG-O 3.47Å; F641-C696 HydrophobicContact CB-CB 3.92Å; F641-C696 HydrophobicContact CD2-CB 4.39Å; G692-C696 PolarHBondContact O-N 3.15Å; G692-C696 PolarHBondContact O-SG 2.83Å; Q693-C696 WeakPolarHBondContact O-CB 3.43Å; Q693-C696 PolarHBondContact O-N 2.88Å; A694-C696 VanDerWaalsContact C-N 3.32Å; A694-C696 PolarHBondContact O-N 3.4Å
697I83.5Confident74.8Confident99 Ų9950.9 Ų50.951%0.50829%0.288SS..Hα-helixtrans-69.8-48.4176.9-67.6163.9000110.1F641 Q693 A694 L695 T700F641-I697 HydrophobicContact CD2-CD1 4.27Å; F641-I697 HydrophobicContact CD2-CG1 3.94Å; F641-I697 HydrophobicContact CE2-CD1 3.69Å; F641-I697 HydrophobicContact CE2-CG1 3.84Å; Q693-I697 WeakPolarHBondContact O-CG1 3.31Å; Q693-I697 PolarHBondContact O-N 3.36Å; Q693-I697 VanDerWaalsContact O-N 3.07Å; A694-I697 PolarHBondContact O-N 3.03Å; A694-I697 VanDerWaalsContact O-N 3.16Å; L695-I697 VanDerWaalsContact C-N 3.31Å; L695-I697 PolarHBondContact O-N 3.19Å; I697-T700 PolarHBondContact O-N 2.92Å; I697-T700 PolarHBondContact O-OG1 3.32Å
698V78.1Confident72.7Confident37 Ų3754.2 Ų54.222%0.22431%0.309CS..Hα-helixtrans-72.7-31.8-176.1173.50000112.8A694 L695 T700 F713 N717 L718A694-V698 PolarHBondContact O-N 2.82Å; L695-V698 PolarHBondContact O-N 2.95Å; V698-T700 PolarHBondContact O-N 3.45Å; V698-F713 HydrophobicContact CG1-CB 4.38Å; V698-F713 HydrophobicContact CG1-CD2 4.47Å; V698-F713 WeakPolarHBondContact O-CD2 3.42Å; V698-N717 HydrophobicContact CG1-CB 3.44Å; V698-N717 VanDerWaalsContact CG1-CB 3.44Å; V698-L718 HydrophobicContact CB-CD2 4.22Å; V698-L718 HydrophobicContact CG2-CD2 3.62Å
699G66.5Low70.6Confident1 Ų157.1 Ų57.11%0.0132%0.324CS..THydrogen-bonded Turntrans-64.5-3.7175.800000115L695 N701 A711L695-G699 PolarHBondContact O-N 3.36Å; G699-N701 PolarHBondContact O-N 2.87Å; G699-A711 WeakPolarHBondContact CA-O 3.47Å
700T58.4Low68.7Low59 Ų5957.2 Ų57.236%0.36232%0.324SS..BIsolated β-bridgetrans-68.5116.916754.20000108.4Y634 L637 I697 V698 P702Y634-T700 HydrophobicContact CD1-CG2 4.42Å; Y634-T700 HydrophobicContact CE1-CG2 4.37Å; L637-T700 HydrophobicContact CD2-CG2 3.58Å; I697-T700 PolarHBondContact O-N 2.92Å; I697-T700 PolarHBondContact O-OG1 3.32Å; V698-T700 PolarHBondContact O-N 3.45Å; T700-P702 WeakPolarHBondContact O-CD 3.36Å; T700-P702 VanDerWaalsContact O-N 3.11Å
701N52.2Low67Low9 Ų954.1 Ų54.15%0.04832%0.318CS..  trans-60.8117.6171.9-177.9-0.8000108.7Y634 G699 R703 C706 V708 N709Y634-N701 PolarHBondContact OH-O 3.24Å; G699-N701 PolarHBondContact O-N 2.87Å; N701-R703 PolarHBondContact ND2-O 3.03Å; N701-R703 PolarHBondContact O-N 3.07Å; N701-R703 PolarHBondContact OD1-N 3.18Å; N701-R703 VanDerWaalsContact OD1-N 3.11Å; N701-R703 PolarHBondContact OD1-O 3.36Å; N701-C706 PolarHBondContact ND2-O 3.43Å; N701-C706 VanDerWaalsContact ND2-O 3.14Å; N701-V708 PolarHBondContact ND2-O 3.45Å; N701-V708 VanDerWaalsContact ND2-O 3.17Å; N701-N709 WeakPolarHBondContact CB-O 3.1Å
702P49.9Very low65.7Low119 Ų11955.4 Ų55.477%0.77333%0.325SS*.SBendtrans-71.5-14.6-177.127.5-33.7000113T700T700-P702 WeakPolarHBondContact O-CD 3.36Å; T700-P702 VanDerWaalsContact O-N 3.11Å
703R47.5Very low64.5Low182 Ų18259.5 Ų59.569%0.68734%0.343SS*.SBendtrans-130.6117.5176.8-72-179.3168.5169.7-4.5108.5N701 D705 C706N701-R703 PolarHBondContact ND2-O 3.03Å; N701-R703 PolarHBondContact O-N 3.07Å; N701-R703 PolarHBondContact OD1-N 3.18Å; N701-R703 VanDerWaalsContact OD1-N 3.11Å; N701-R703 PolarHBondContact OD1-O 3.36Å; R703-D705 PolarHBondContact O-N 3.32Å; R703-C706 PolarHBondContact O-N 3.21Å
704N53.6Low63.8Low122 Ų12258.8 Ų58.865%0.65234%0.341SS*.THydrogen-bonded Turntrans-54.64.1174.2-73.3-14.7000115.3Y634Y634-N704 PolarHBondContact OH-OD1 3.07Å
705D52.8Low63.5Low140 Ų14058.4 Ų58.475%0.74934%0.337SS*.THydrogen-bonded Turntrans-101.2-17.3-169.8-50.1-27.7000113.8R703R703-D705 PolarHBondContact O-N 3.32Å
706C47.8Very low63.1Low79 Ų7961.9 Ų61.953%0.53436%0.356SS..SBendtrans-81.2122.9171.5-60.20000108.1N701 R703 V708N701-C706 PolarHBondContact ND2-O 3.43Å; N701-C706 VanDerWaalsContact ND2-O 3.14Å; R703-C706 PolarHBondContact O-N 3.21Å; C706-V708 PolarHBondContact O-N 3.47Å
707G54.8Low62.9Low88 Ų8866.3 Ų66.391%0.90738%0.379SS*.SBendtrans-59.814.5-169.400000118.5
708V52.6Low63.1Low77 Ų7761.9 Ų61.947%0.46736%0.357SS..  trans-128.5123.3169.6-172.70000108.8F626 N701 C706 V710F626-V708 HydrophobicContact CE1-CG1 4.49Å; N701-V708 PolarHBondContact ND2-O 3.45Å; N701-V708 VanDerWaalsContact ND2-O 3.17Å; C706-V708 PolarHBondContact O-N 3.47Å; V708-V710 WeakPolarHBondContact CG1-O 3.3Å
709N50.1Low63.5Low62 Ų6263 Ų6333%0.33237%0.366SS..SBendtrans-71.2-30.4-175.2-72.4-15.3000114.1I632 N701I632-N709 WeakPolarHBondContact O-CB 3.49Å; I632-N709 PolarHBondContact O-ND2 3.19Å; N701-N709 WeakPolarHBondContact CB-O 3.1Å
710V55.6Low64.4Low2 Ų266.6 Ų66.61%0.01239%0.391CS..BIsolated β-bridgetrans-148.7127.3-178.2173.30000109.1I632 L637 V708I632-V710 HydrophobicContact CB-CB 4Å; I632-V710 HydrophobicContact CB-CG2 4.08Å; I632-V710 HydrophobicContact CD1-CB 3.72Å; I632-V710 HydrophobicContact CD1-CG1 4.23Å; I632-V710 WeakPolarHBondContact CD1-O 3.34Å; I632-V710 HydrophobicContact CG1-CB 4.45Å; I632-V710 HydrophobicContact CG2-CB 3.62Å; I632-V710 HydrophobicContact CG2-CG1 4.23Å; I632-V710 HydrophobicContact CG2-CG2 3.42Å; I632-V710 VanDerWaalsContact CG2-CG2 3.42Å; L637-V710 HydrophobicContact CD1-CG1 4Å; L637-V710 HydrophobicContact CD2-CG1 4.07Å; L637-V710 HydrophobicContact CD2-CG2 4.13Å; V708-V710 WeakPolarHBondContact CG1-O 3.3Å
711A60.9Low65.9Low23 Ų2369 Ų6919%0.1941%0.406CS..  trans-137.1146.6169.700000108.7G699 F713G699-A711 WeakPolarHBondContact CA-O 3.47Å; A711-F713 HydrophobicContact CB-CD1 4.47Å; A711-F713 HydrophobicContact CB-CE1 4.2Å; A711-F713 HydrophobicContact CB-CZ 4.31Å; A711-F713 WeakPolarHBondContact O-CD2 3.41Å; A711-F713 PolarHBondContact O-N 3.22Å
712N65.2Low67.7Low32 Ų3270.9 Ų70.917%0.17142%0.418CS..  trans-70.3100.3162.7-175.10.2000107.1P618 D619 L621 L623 G714P618-N712 PolarHBondContact O-ND2 3.4Å; D619-N712 PolarHBondContact O-ND2 2.95Å; L621-N712 WeakPolarHBondContact O-CB 3.29Å; L621-N712 PolarHBondContact O-ND2 2.96Å; L621-N712 VanDerWaalsContact O-ND2 3.07Å; L623-N712 HydrophobicContact CD1-CB 4.19Å; L623-N712 HydrophobicContact CG-CB 4.45Å; N712-G714 PolarHBondContact O-N 3.06Å; N712-G714 WeakPolarHBondContact OD1-CA 3.45Å; N712-G714 PolarHBondContact OD1-N 3.43Å
713F67.6Low69.7Low86 Ų8666.8 Ų66.838%0.37739%0.387SS..  trans-72.1-2.6175.8-62.6-71.6000112.2V698 A711 N717V698-F713 HydrophobicContact CG1-CB 4.38Å; V698-F713 HydrophobicContact CG1-CD2 4.47Å; V698-F713 WeakPolarHBondContact O-CD2 3.42Å; A711-F713 HydrophobicContact CB-CD1 4.47Å; A711-F713 HydrophobicContact CB-CE1 4.2Å; A711-F713 HydrophobicContact CB-CZ 4.31Å; A711-F713 WeakPolarHBondContact O-CD2 3.41Å; A711-F713 PolarHBondContact O-N 3.22Å; F713-N717 HydrophobicContact CB-CB 3.96Å; F713-N717 WeakPolarHBondContact CB-ND2 3.38Å; F713-N717 PolarHBondContact O-ND2 2.9Å
714G77Confident71.7Confident5 Ų562 Ų625%0.05238%0.378CS..  trans83.4167.7177.700000113.8D619 N712 N716 N717D619-G714 WeakPolarHBondContact OD1-CA 3.28Å; N712-G714 PolarHBondContact O-N 3.06Å; N712-G714 WeakPolarHBondContact OD1-CA 3.45Å; N712-G714 PolarHBondContact OD1-N 3.43Å; G714-N716 PolarHBondContact O-N 3.18Å; G714-N717 PolarHBondContact O-N 2.72Å; G714-N717 VanDerWaalsContact O-N 3.1Å
715V84.2Confident73.5Confident1 Ų160.3 Ų60.31%0.00637%0.369CS..G310 helixtrans-59.5-29.6-176.3179.80000112.1P618 D619 L691 L695 N717 L718 N763 L764P618-V715 HydrophobicContact CB-CG2 3.74Å; P618-V715 HydrophobicContact CG-CG2 3.43Å; P618-V715 VanDerWaalsContact CG-CG2 3.43Å; D619-V715 WeakPolarHBondContact OD1-CG2 3.43Å; D619-V715 PolarHBondContact OD1-N 3.31Å; L691-V715 HydrophobicContact CD1-CG2 4.2Å; L695-V715 HydrophobicContact CD2-CG2 4.31Å; V715-N717 PolarHBondContact O-N 3.12Å; V715-N717 VanDerWaalsContact O-N 3.16Å; V715-L718 HydrophobicContact CG1-CD1 4.01Å; V715-L718 VanDerWaalsContact O-CB 3.32Å; V715-L718 WeakPolarHBondContact O-CB 3.29Å; V715-L718 VanDerWaalsContact O-CG 3.3Å; V715-L718 WeakPolarHBondContact O-CG 3.44Å; V715-L718 PolarHBondContact O-N 3.17Å; V715-L718 VanDerWaalsContact O-N 3.09Å; V715-N763 VanDerWaalsContact CG1-O 3.24Å; V715-N763 WeakPolarHBondContact CG1-O 3.32Å; V715-L764 HydrophobicContact CG1-CD2 3.75Å; V715-L764 HydrophobicContact CG1-CG 4.47Å
716N81.4Confident75.5Confident74 Ų7453.9 Ų53.940%0.39634%0.335SS..G310 helixtrans-59.8-25.5177.5-77.4-38.8000114.1G714G714-N716 PolarHBondContact O-N 3.18Å
717N81.5Confident77.7Confident95 Ų9550.3 Ų50.351%0.50831%0.311SS..G310 helixtrans-90-0.3-179.5-74-68.9000113.5V698 F713 G714 V715V698-N717 HydrophobicContact CG1-CB 3.44Å; V698-N717 VanDerWaalsContact CG1-CB 3.44Å; F713-N717 HydrophobicContact CB-CB 3.96Å; F713-N717 WeakPolarHBondContact CB-ND2 3.38Å; F713-N717 PolarHBondContact O-ND2 2.9Å; G714-N717 PolarHBondContact O-N 2.72Å; G714-N717 VanDerWaalsContact O-N 3.1Å; V715-N717 PolarHBondContact O-N 3.12Å; V715-N717 VanDerWaalsContact O-N 3.16Å
718L86.9Confident79.5Confident6 Ų650.9 Ų50.93%0.03129%0.293CS..SBendtrans-68.6149.6171.8-59.8-176.9000111.5L691 A694 L695 V698 V715 R723 L726L691-L718 HydrophobicContact CD1-CD1 3.62Å; A694-L718 HydrophobicContact CB-CD1 4.15Å; A694-L718 HydrophobicContact CB-CD2 3.64Å; L695-L718 HydrophobicContact CD2-CD2 4.18Å; V698-L718 HydrophobicContact CB-CD2 4.22Å; V698-L718 HydrophobicContact CG2-CD2 3.62Å; V715-L718 HydrophobicContact CG1-CD1 4.01Å; V715-L718 VanDerWaalsContact O-CB 3.32Å; V715-L718 WeakPolarHBondContact O-CB 3.29Å; V715-L718 VanDerWaalsContact O-CG 3.3Å; V715-L718 WeakPolarHBondContact O-CG 3.44Å; V715-L718 PolarHBondContact O-N 3.17Å; V715-L718 VanDerWaalsContact O-N 3.09Å; L718-R723 HydrophobicContact CB-CG 3.73Å; L718-R723 HydrophobicContact CD1-CG 4.39Å; L718-R723 PolarHBondContact O-NE 3.48Å; L718-L726 HydrophobicContact CD1-CD1 4.43Å
719S87.6Confident81.5Confident61 Ų6150.3 Ų50.343%0.42728%0.283SS..  trans-55.7146.117486.30000111T721 T722 R723S719-T721 PolarHBondContact O-N 3.35Å; S719-T722 PolarHBondContact O-N 3.23Å; S719-T722 WeakPolarHBondContact OG-CB 3.08Å; S719-T722 PolarHBondContact OG-N 3.3Å; S719-T722 VanDerWaalsContact OG-N 3.08Å; S719-T722 PolarHBondContact OG-OG1 3.15Å; S719-R723 PolarHBondContact O-N 3.47Å
720S85.9Confident83.7Confident77 Ų7747.4 Ų47.454%0.53827%0.267SS..Hα-helixtrans-55.8-42.3177.549.10000111.5T722 R723 T724S720-T722 PolarHBondContact O-N 3.2Å; S720-R723 PolarHBondContact O-N 3.3Å; S720-T724 PolarHBondContact O-N 3.2Å; S720-T724 PolarHBondContact O-OG1 3.41Å; S720-T724 VanDerWaalsContact O-OG1 3.09Å
721T89.5Confident85.5Confident108 Ų10849.8 Ų49.866%0.66328%0.279SS*.Hα-helixtrans-59.6-47177.5-49.80000112.3S719 R723 T724 D725S719-T721 PolarHBondContact O-N 3.35Å; T721-R723 PolarHBondContact O-N 2.66Å; T721-T724 PolarHBondContact O-N 3.09Å; T721-D725 PolarHBondContact O-N 3.38Å
722T90.3Very high87.1Confident50 Ų5053.1 Ų53.131%0.30729%0.291SS..Hα-helixtrans-63.3-42.3179.1-54.90000111.6A694 S719 S720 D725 L726A694-T722 HydrophobicContact CB-CG2 3.94Å; S719-T722 PolarHBondContact O-N 3.23Å; S719-T722 WeakPolarHBondContact OG-CB 3.08Å; S719-T722 PolarHBondContact OG-N 3.3Å; S719-T722 VanDerWaalsContact OG-N 3.08Å; S719-T722 PolarHBondContact OG-OG1 3.15Å; S720-T722 PolarHBondContact O-N 3.2Å; T722-D725 PolarHBondContact O-N 3.37Å; T722-L726 HydrophobicContact CG2-CD1 4.06Å; T722-L726 HydrophobicContact CG2-CG 4.47Å; T722-L726 WeakPolarHBondContact O-CG 3.47Å; T722-L726 PolarHBondContact O-N 3.13Å
723R90.9Very high88.6Confident32 Ų3251.6 Ų51.612%0.12128%0.283CS..Hα-helixtrans-62.7-45.9178.2-74.2-174.2-66.5162.3-3.4112.1L718 S719 S720 T721 D725 L726 A727 L764L718-R723 HydrophobicContact CB-CG 3.73Å; L718-R723 HydrophobicContact CD1-CG 4.39Å; L718-R723 PolarHBondContact O-NE 3.48Å; S719-R723 PolarHBondContact O-N 3.47Å; S720-R723 PolarHBondContact O-N 3.3Å; T721-R723 PolarHBondContact O-N 2.66Å; R723-D725 PolarHBondContact O-N 3.07Å; R723-L726 PolarHBondContact O-N 2.97Å; R723-A727 VanDerWaalsContact O-CB 3.26Å; R723-A727 WeakPolarHBondContact O-CB 3.26Å; R723-A727 PolarHBondContact O-N 2.71Å; R723-L764 WeakPolarHBondContact CB-O 3.34Å; R723-L764 WeakPolarHBondContact CD-O 3.33Å
724T89.8Confident90Very high82 Ų8249.3 Ų49.350%0.50327%0.272SS..Hα-helixtrans-63.1-41178-57.90000112.1S720 T721 A727 N728S720-T724 PolarHBondContact O-N 3.2Å; S720-T724 PolarHBondContact O-OG1 3.41Å; S720-T724 VanDerWaalsContact O-OG1 3.09Å; T721-T724 PolarHBondContact O-N 3.09Å; T724-A727 PolarHBondContact O-N 3.02Å; T724-N728 WeakPolarHBondContact O-CB 3.39Å; T724-N728 VanDerWaalsContact O-CG 3.26Å; T724-N728 PolarHBondContact O-N 3.49Å; T724-N728 PolarHBondContact O-ND2 2.87Å
725D92.4Very high90.9Very high87 Ų8751.3 Ų51.347%0.46529%0.288SS..Hα-helixtrans-61.9-48.7176.1-177.361.6000112.1R690 T721 T722 R723 A727 N728 R729R690-D725 IonicContact NH1-OD2 3.46Å; T721-D725 PolarHBondContact O-N 3.38Å; T722-D725 PolarHBondContact O-N 3.37Å; R723-D725 PolarHBondContact O-N 3.07Å; D725-A727 VanDerWaalsContact C-N 3.35Å; D725-A727 PolarHBondContact O-N 3.05Å; D725-N728 PolarHBondContact O-N 2.91Å; D725-R729 PolarHBondContact O-N 3.48Å
726L94.5Very high91.4Very high4 Ų454.8 Ų54.82%0.02130%0.301CS..Hα-helixtrans-62.1-42177.4-69.1174.2000111.8L687 R690 L691 L718 T722 R723 R729 L730 L764L687-L726 HydrophobicContact CD1-CB 4.34Å; L687-L726 HydrophobicContact CD1-CD2 3.66Å; L687-L726 HydrophobicContact CG-CD2 4.34Å; R690-L726 HydrophobicContact CB-CD2 3.89Å; L691-L726 HydrophobicContact CB-CD1 4.27Å; L691-L726 HydrophobicContact CD1-CD1 3.9Å; L718-L726 HydrophobicContact CD1-CD1 4.43Å; T722-L726 HydrophobicContact CG2-CD1 4.06Å; T722-L726 HydrophobicContact CG2-CG 4.47Å; T722-L726 WeakPolarHBondContact O-CG 3.47Å; T722-L726 PolarHBondContact O-N 3.13Å; R723-L726 PolarHBondContact O-N 2.97Å; L726-R729 PolarHBondContact O-N 3.22Å; L726-L730 WeakPolarHBondContact O-CB 3.47Å; L726-L730 PolarHBondContact O-N 2.86Å; L726-L764 HydrophobicContact CB-CD1 4.03Å; L726-L764 HydrophobicContact CB-CD2 3.93Å; L726-L764 HydrophobicContact CD1-CD2 3.99Å
727A92.6Very high92.2Very high5 Ų551.6 Ų51.64%0.04128%0.284CS..Hα-helixtrans-63.3-44.3178.700000111.9R723 T724 D725 R729 L730 L731 F761 L764R723-A727 VanDerWaalsContact O-CB 3.26Å; R723-A727 WeakPolarHBondContact O-CB 3.26Å; R723-A727 PolarHBondContact O-N 2.71Å; T724-A727 PolarHBondContact O-N 3.02Å; D725-A727 VanDerWaalsContact C-N 3.35Å; D725-A727 PolarHBondContact O-N 3.05Å; A727-R729 PolarHBondContact O-N 3.32Å; A727-L730 PolarHBondContact O-N 2.84Å; A727-L731 WeakPolarHBondContact O-CG 3.34Å; A727-L731 PolarHBondContact O-N 3.15Å; A727-F761 HydrophobicContact CB-CD2 4.05Å; A727-F761 HydrophobicContact CB-CE2 3.82Å; A727-L764 HydrophobicContact CB-CB 4.25Å; A727-L764 HydrophobicContact CB-CD1 4.37Å
728N92.7Very high92.9Very high99 Ų9950.4 Ų50.453%0.52928%0.275SS..Hα-helixtrans-63.2-43177.2-72.8-25.7000111.9T724 D725 L730 L731 E732T724-N728 WeakPolarHBondContact O-CB 3.39Å; T724-N728 VanDerWaalsContact O-CG 3.26Å; T724-N728 PolarHBondContact O-N 3.49Å; T724-N728 PolarHBondContact O-ND2 2.87Å; D725-N728 PolarHBondContact O-N 2.91Å; N728-L730 VanDerWaalsContact C-N 3.33Å; N728-L730 PolarHBondContact O-N 2.94Å; N728-L731 PolarHBondContact O-N 2.97Å; N728-E732 PolarHBondContact O-N 3.22Å
729R95.5Very high93.3Very high65 Ų6556.4 Ų56.425%0.24530%0.302CS..Hα-helixtrans-65.5-38.1176.7-175.158.6176.3-179.32.4111.9D683 L687 D725 L726 A727 E732 I733D683-R729 IonicContact OD1-CZ 3.56Å; D683-R729 IonicContact OD1-NH2 3.87Å; D683-R729 PolarHBondContact OD1-NH2 2.82Å; D683-R729 IonicContact OD2-NH2 3.86Å; L687-R729 HydrophobicContact CD1-CB 3.92Å; L687-R729 HydrophobicContact CD1-CG 3.95Å; D725-R729 PolarHBondContact O-N 3.48Å; L726-R729 PolarHBondContact O-N 3.22Å; A727-R729 PolarHBondContact O-N 3.32Å; R729-E732 IonicContact CZ-OE1 3.65Å; R729-E732 IonicContact CZ-OE2 2.74Å; R729-E732 IonicContact NH1-OE1 3.92Å; R729-E732 PolarHBondContact NH1-OE1 3.16Å; R729-E732 IonicContact NH1-OE2 3.7Å; R729-E732 PolarHBondContact NH1-OE2 2.95Å; R729-E732 PolarHBondContact O-N 2.91Å; R729-I733 HydrophobicContact CG-CD1 4.15Å; R729-I733 WeakPolarHBondContact O-CG1 3.3Å; R729-I733 PolarHBondContact O-N 2.96Å; R729-I733 VanDerWaalsContact O-N 3.08Å
730L95.7Very high93.7Very high1 Ų154 Ų541%0.00529%0.287CS..Hα-helixtrans-61.8-42.6176.1-17864000111.8M684 L687 L726 A727 N728 E732 I733 R734 F757 L760 F761 L764M684-L730 HydrophobicContact CE-CD1 3.85Å; M684-L730 HydrophobicContact SD-CD1 4.1Å; L687-L730 HydrophobicContact CD2-CB 4.08Å; L687-L730 HydrophobicContact CD2-CD1 3.74Å; L687-L730 HydrophobicContact CD2-CG 4.45Å; L726-L730 WeakPolarHBondContact O-CB 3.47Å; L726-L730 PolarHBondContact O-N 2.86Å; A727-L730 PolarHBondContact O-N 2.84Å; N728-L730 VanDerWaalsContact C-N 3.33Å; N728-L730 PolarHBondContact O-N 2.94Å; L730-E732 VanDerWaalsContact C-N 3.34Å; L730-E732 PolarHBondContact O-N 3.4Å; L730-I733 PolarHBondContact O-N 3.34Å; L730-R734 WeakPolarHBondContact O-CB 3.4Å; L730-R734 PolarHBondContact O-N 3.1Å; L730-F757 HydrophobicContact CD1-CD1 3.66Å; L730-F757 HydrophobicContact CD1-CE1 4.3Å; L730-F757 HydrophobicContact CG-CD1 4.47Å; L730-L760 HydrophobicContact CD1-CD2 3.95Å; L730-L760 HydrophobicContact CD2-CB 3.96Å; L730-L760 HydrophobicContact CD2-CD2 4Å; L730-L760 HydrophobicContact CD2-CG 3.83Å; L730-F761 HydrophobicContact CD2-CB 3.81Å; L730-F761 HydrophobicContact CD2-CD2 4.5Å; L730-L764 HydrophobicContact CD2-CD1 4.03Å
731L93.9Very high94.1Very high52 Ų5250.7 Ų50.727%0.27226%0.262SS..Hα-helixtrans-62.6-39.2176.6-70.2176.6000112.4A727 N728 R734 A735 F761 L777A727-L731 WeakPolarHBondContact O-CG 3.34Å; A727-L731 PolarHBondContact O-N 3.15Å; N728-L731 PolarHBondContact O-N 2.97Å; L731-R734 PolarHBondContact O-N 3.38Å; L731-A735 PolarHBondContact O-N 2.86Å; L731-F761 HydrophobicContact CD1-CD2 4.43Å; L731-F761 HydrophobicContact CD1-CE2 3.58Å; L731-F761 HydrophobicContact CD1-CZ 4Å; L731-F761 HydrophobicContact CD2-CD2 3.9Å; L731-F761 HydrophobicContact CD2-CE2 3.77Å; L731-F761 HydrophobicContact CD2-CG 4.49Å; L731-F761 HydrophobicContact CD2-CZ 4.23Å; L731-F761 HydrophobicContact CG-CD2 3.95Å; L731-F761 HydrophobicContact CG-CE2 3.59Å; L731-F761 HydrophobicContact CG-CZ 4.34Å; L731-L777 HydrophobicContact CD2-CD2 3.78Å
732E95.5Very high94.4Very high94 Ų9449 Ų4944%0.43925%0.249SC..Hα-helixtrans-64-41.8175.4-171.1-165.9154.800112.1N728 R729 L730 R736N728-E732 PolarHBondContact O-N 3.22Å; R729-E732 IonicContact CZ-OE1 3.65Å; R729-E732 IonicContact CZ-OE2 2.74Å; R729-E732 IonicContact NH1-OE1 3.92Å; R729-E732 PolarHBondContact NH1-OE1 3.16Å; R729-E732 IonicContact NH1-OE2 3.7Å; R729-E732 PolarHBondContact NH1-OE2 2.95Å; R729-E732 PolarHBondContact O-N 2.91Å; L730-E732 VanDerWaalsContact C-N 3.34Å; L730-E732 PolarHBondContact O-N 3.4Å; E732-R736 PolarHBondContact O-N 3.47Å
733I96.5Very high94.6Very high0 Ų048.7 Ų48.70%025%0.249CC..Hα-helixtrans-65.8-45.3175.3-62.6166000109.9L680 D683 L687 R729 L730 A735 R736 F737 F757L680-I733 HydrophobicContact CD2-CG2 3.94Å; D683-I733 HydrophobicContact CB-CD1 3.89Å; D683-I733 HydrophobicContact CB-CG1 4.02Å; L687-I733 HydrophobicContact CB-CD1 4.39Å; R729-I733 HydrophobicContact CG-CD1 4.15Å; R729-I733 WeakPolarHBondContact O-CG1 3.3Å; R729-I733 PolarHBondContact O-N 2.96Å; R729-I733 VanDerWaalsContact O-N 3.08Å; L730-I733 PolarHBondContact O-N 3.34Å; I733-A735 VanDerWaalsContact C-N 3.33Å; I733-A735 PolarHBondContact O-N 2.68Å; I733-R736 PolarHBondContact O-N 2.96Å; I733-F737 WeakPolarHBondContact O-CB 3.41Å; I733-F737 PolarHBondContact O-N 2.83Å; I733-F757 HydrophobicContact CG2-CE1 3.91Å
734R95.6Very high94.8Very high38 Ų3847.5 Ų47.514%0.14324%0.244CC..Hα-helixtrans-54.7-46.1178-175.6-175.1179.2-99.413.4111.8L730 L731 F737 Q738 L754 F757 D758 L777L730-R734 WeakPolarHBondContact O-CB 3.4Å; L730-R734 PolarHBondContact O-N 3.1Å; L731-R734 PolarHBondContact O-N 3.38Å; R734-F737 WeakPolarHBondContact O-CB 3.47Å; R734-F737 PolarHBondContact O-N 3.02Å; R734-Q738 PolarHBondContact O-N 3.24Å; R734-L754 HydrophobicContact CG-CD2 3.72Å; R734-F757 HydrophobicContact CB-CB 4.29Å; R734-F757 HydrophobicContact CB-CD1 3.9Å; R734-F757 HydrophobicContact CB-CG 4.18Å; R734-F757 HydrophobicContact CG-CB 3.94Å; R734-F757 HydrophobicContact CG-CD1 4.33Å; R734-F757 HydrophobicContact CG-CG 4.09Å; R734-D758 IonicContact CZ-OD1 3.68Å; R734-D758 IonicContact NE-OD1 3.01Å; R734-D758 PolarHBondContact NE-OD1 3.36Å; R734-D758 IonicContact NH2-OD1 3.36Å; R734-D758 PolarHBondContact NH2-OD1 2.63Å; R734-D758 VanDerWaalsContact NH2-OD1 3.09Å; R734-D758 IonicContact NH2-OD2 3.24Å; R734-L777 PolarHBondContact NH2-O 3.16Å
735A95.4Very high95.1Very high46 Ų4644 Ų4438%0.3822%0.222SC..Hα-helixtrans-62.9-44.3178.900000112.4L731 I733 Q738 H739L731-A735 PolarHBondContact O-N 2.86Å; I733-A735 VanDerWaalsContact C-N 3.33Å; I733-A735 PolarHBondContact O-N 2.68Å; A735-Q738 PolarHBondContact O-N 3.05Å; A735-H739 PolarHBondContact O-CD2 2.89Å; A735-H739 PolarHBondContact O-N 3.34Å
736R96.7Very high95.2Very high74 Ų7441.1 Ų41.128%0.27921%0.207SC..Hα-helixtrans-66.8-37.4175.7-73.9-174-68.7143.8-4.5112.2L680 D683 E732 I733 H739 A740L680-R736 HydrophobicContact CD2-CB 3.62Å; D683-R736 IonicContact OD2-CZ 3.35Å; D683-R736 IonicContact OD2-NH1 2.85Å; D683-R736 PolarHBondContact OD2-NH1 2.83Å; D683-R736 IonicContact OD2-NH2 3.41Å; D683-R736 PolarHBondContact OD2-NH2 2.87Å; E732-R736 PolarHBondContact O-N 3.47Å; I733-R736 PolarHBondContact O-N 2.96Å; R736-H739 PolarHBondContact O-N 2.94Å; R736-A740 PolarHBondContact O-N 2.83Å; R736-A740 VanDerWaalsContact O-N 3.09Å
737F96.7Very high95.1Very high8 Ų844.6 Ų44.64%0.03523%0.23CC..Hα-helixtrans-60.7-43.5175.4173.2-101.1000111.6E534 I535 L680 I733 R734 H739 A740 W741 A753 L754 F757E534-F737 HydrophobicContact CB-CZ 4.48Å; E534-F737 VanDerWaalsContact O-CE2 3.31Å; E534-F737 WeakPolarHBondContact O-CE2 3.24Å; E534-F737 WeakPolarHBondContact O-CZ 3.49Å; I535-F737 HydrophobicContact CG1-CD2 4.25Å; I535-F737 HydrophobicContact CG1-CE2 4.46Å; L680-F737 HydrophobicContact CD1-CB 4.4Å; L680-F737 HydrophobicContact CD2-CB 4.29Å; I733-F737 WeakPolarHBondContact O-CB 3.41Å; I733-F737 PolarHBondContact O-N 2.83Å; R734-F737 WeakPolarHBondContact O-CB 3.47Å; R734-F737 PolarHBondContact O-N 3.02Å; F737-H739 VanDerWaalsContact C-N 3.31Å; F737-H739 PolarHBondContact O-N 3.26Å; F737-A740 PolarHBondContact O-N 3.3Å; F737-W741 HydrophobicContact CE1-CB 4.49Å; F737-W741 HydrophobicContact CE1-CD2 4.47Å; F737-W741 HydrophobicContact CE1-CE3 4.15Å; F737-W741 AromaticContact CE2-CE3 3.79Å; F737-W741 HydrophobicContact CE2-CE3 3.79Å; F737-W741 HydrophobicContact CE2-CZ3 4.35Å; F737-W741 HydrophobicContact CZ-CB 4.5Å; F737-W741 HydrophobicContact CZ-CD2 4.04Å; F737-W741 AromaticContact CZ-CE3 3.31Å; F737-W741 HydrophobicContact CZ-CE3 3.31Å; F737-W741 AromaticContact CZ-CZ3 3.82Å; F737-W741 HydrophobicContact CZ-CZ3 3.82Å; F737-W741 VanDerWaalsContact O-CB 3.3Å; F737-W741 WeakPolarHBondContact O-CB 3.35Å; F737-W741 PolarHBondContact O-N 2.79Å; F737-A753 HydrophobicContact CE1-CB 4.13Å; F737-A753 HydrophobicContact CZ-CB 4.22Å; F737-L754 HydrophobicContact CD1-CD2 3.94Å; F737-L754 HydrophobicContact CE1-CD2 4.26Å; F737-F757 HydrophobicContact CB-CE2 4.34Å; F737-F757 HydrophobicContact CB-CZ 3.97Å; F737-F757 HydrophobicContact CD1-CD2 4.18Å; F737-F757 AromaticContact CD1-CE2 3.46Å; F737-F757 HydrophobicContact CD1-CE2 3.46Å; F737-F757 VanDerWaalsContact CD1-CE2 3.46Å; F737-F757 AromaticContact CD1-CZ 3.98Å; F737-F757 HydrophobicContact CD1-CZ 3.98Å; F737-F757 HydrophobicContact CD2-CE2 4.25Å; F737-F757 HydrophobicContact CD2-CZ 4.19Å; F737-F757 HydrophobicContact CE1-CD2 4.4Å; F737-F757 AromaticContact CE1-CE2 3.71Å; F737-F757 HydrophobicContact CE1-CE2 3.71Å; F737-F757 HydrophobicContact CE2-CE2 4.47Å; F737-F757 AromaticContact CG-CE2 3.74Å; F737-F757 HydrophobicContact CG-CE2 3.74Å; F737-F757 AromaticContact CG-CZ 3.76Å; F737-F757 HydrophobicContact CG-CZ 3.76Å; F737-F757 HydrophobicContact CZ-CE2 4.21Å
738Q95.9Very high95.2Very high69 Ų6950.5 Ų50.532%0.32227%0.265SS..Hα-helixtrans-55.7-44.7175.8175.6173.33.300112.3R734 A735 W741 L742 L750R734-Q738 PolarHBondContact O-N 3.24Å; A735-Q738 PolarHBondContact O-N 3.05Å; Q738-W741 PolarHBondContact O-N 3.18Å; Q738-L742 HydrophobicContact CG-CD1 4.05Å; Q738-L742 WeakPolarHBondContact O-CB 3.38Å; Q738-L742 VanDerWaalsContact O-CG 3.31Å; Q738-L742 WeakPolarHBondContact O-CG 3.2Å; Q738-L742 PolarHBondContact O-N 3.09Å; Q738-L750 HydrophobicContact CB-CD1 4.33Å; Q738-L750 HydrophobicContact CG-CD1 4.1Å; Q738-L750 HydrophobicContact CG-CD2 3.75Å
739H95.6Very high95.2Very high132 Ų13246.8 Ų46.861%0.61125%0.246SC*.Hα-helixtrans-65.1-44.7177.5-70.3-64.2000112.6A735 R736 F737 W741 S743A735-H739 PolarHBondContact O-CD2 2.89Å; A735-H739 PolarHBondContact O-N 3.34Å; R736-H739 PolarHBondContact O-N 2.94Å; F737-H739 VanDerWaalsContact C-N 3.31Å; F737-H739 PolarHBondContact O-N 3.26Å; H739-W741 VanDerWaalsContact C-N 3.35Å; H739-S743 PolarHBondContact O-N 3.06Å; H739-S743 PolarHBondContact O-OG 3.06Å
740A95.4Very high95.1Very high12 Ų1244.6 Ų44.610%0.09924%0.239CC..Hα-helixtrans-63.1-42.1176.600000111.5L673 E677 L680 R736 F737 S743L673-A740 HydrophobicContact CD1-CB 4.32Å; E677-A740 HydrophobicContact CG-CB 4.4Å; L680-A740 HydrophobicContact CD1-CB 3.68Å; R736-A740 PolarHBondContact O-N 2.83Å; R736-A740 VanDerWaalsContact O-N 3.09Å; F737-A740 PolarHBondContact O-N 3.3Å; A740-S743 WeakPolarHBondContact O-CB 3.38Å; A740-S743 PolarHBondContact O-N 2.83Å
741W95.4Very high94.9Very high7 Ų748.4 Ų48.43%0.02727%0.266CS..Hα-helixtrans-60.5-50.7179-172.9-90.1000112C318 R319 E534 F737 Q738 H739 S743 R744 N745 T749 L750 A753C318-W741 HydrophobicContact CB-CH2 4.28Å; C318-W741 HydrophobicContact CB-CZ2 4.27Å; C318-W741 WeakPolarHBondContact O-CZ2 3.35Å; R319-W741 HydrophobicContact CB-CH2 3.87Å; R319-W741 HydrophobicContact CB-CZ3 4.48Å; R319-W741 HydrophobicContact CG-CH2 4.32Å; E534-W741 HydrophobicContact CB-CH2 4.1Å; E534-W741 HydrophobicContact CB-CZ3 4Å; E534-W741 WeakPolarHBondContact O-CZ3 3.44Å; F737-W741 HydrophobicContact CE1-CB 4.49Å; F737-W741 HydrophobicContact CE1-CD2 4.47Å; F737-W741 HydrophobicContact CE1-CE3 4.15Å; F737-W741 AromaticContact CE2-CE3 3.79Å; F737-W741 HydrophobicContact CE2-CE3 3.79Å; F737-W741 HydrophobicContact CE2-CZ3 4.35Å; F737-W741 HydrophobicContact CZ-CB 4.5Å; F737-W741 HydrophobicContact CZ-CD2 4.04Å; F737-W741 AromaticContact CZ-CE3 3.31Å; F737-W741 HydrophobicContact CZ-CE3 3.31Å; F737-W741 AromaticContact CZ-CZ3 3.82Å; F737-W741 HydrophobicContact CZ-CZ3 3.82Å; F737-W741 VanDerWaalsContact O-CB 3.3Å; F737-W741 WeakPolarHBondContact O-CB 3.35Å; F737-W741 PolarHBondContact O-N 2.79Å; Q738-W741 PolarHBondContact O-N 3.18Å; H739-W741 VanDerWaalsContact C-N 3.35Å; W741-S743 PolarHBondContact O-N 2.73Å; W741-S743 VanDerWaalsContact O-N 3.13Å; W741-R744 PolarHBondContact O-N 2.96Å; W741-R744 VanDerWaalsContact O-N 3.08Å; W741-N745 HydrophobicContact CD2-CB 4.02Å; W741-N745 VanDerWaalsContact CE3-ND2 3.25Å; W741-N745 HydrophobicContact CG-CB 4.21Å; W741-N745 HydrophobicContact CZ2-CB 4.06Å; W741-N745 WeakPolarHBondContact O-CB 3.23Å; W741-N745 PolarHBondContact O-N 2.82Å; W741-N745 PolarHBondContact O-ND2 3.38Å; W741-T749 WeakPolarHBondContact CZ2-OG1 3.23Å; W741-T749 PolarHBondContact NE1-OG1 3.26Å; W741-L750 HydrophobicContact CB-CD1 4.1Å; W741-L750 HydrophobicContact CG-CD1 3.94Å; W741-A753 HydrophobicContact CD2-CB 4.09Å; W741-A753 HydrophobicContact CE3-CB 4.23Å; W741-A753 HydrophobicContact CH2-CB 3.7Å; W741-A753 HydrophobicContact CZ2-CB 3.56Å; W741-A753 HydrophobicContact CZ3-CB 4.05Å
742L96Very high94.8Very high72 Ų7249.4 Ų49.438%0.37727%0.271SS..Hα-helixtrans-65.9-13.7179.5-68.9174.8000113.5Q738 P747 L750Q738-L742 HydrophobicContact CG-CD1 4.05Å; Q738-L742 WeakPolarHBondContact O-CB 3.38Å; Q738-L742 VanDerWaalsContact O-CG 3.31Å; Q738-L742 WeakPolarHBondContact O-CG 3.2Å; Q738-L742 PolarHBondContact O-N 3.09Å; L742-P747 HydrophobicContact CD2-CB 3.82Å; L742-P747 HydrophobicContact CD2-CG 4.14Å; L742-L750 HydrophobicContact CD1-CD2 4.15Å; L742-L750 HydrophobicContact CD2-CD2 4.01Å; L742-L750 HydrophobicContact CG-CD2 4.14Å
743S95Very high94.6Very high44 Ų4444.9 Ų44.931%0.30825%0.25SS..THydrogen-bonded Turntrans-81.9-16.6175.5-57.60000113.3Y669 H739 A740 W741Y669-S743 PolarHBondContact OH-OG 3.11Å; H739-S743 PolarHBondContact O-N 3.06Å; H739-S743 PolarHBondContact O-OG 3.06Å; A740-S743 WeakPolarHBondContact O-CB 3.38Å; A740-S743 PolarHBondContact O-N 2.83Å; W741-S743 PolarHBondContact O-N 2.73Å; W741-S743 VanDerWaalsContact O-N 3.13Å
744R94.1Very high94.5Very high6 Ų645.6 Ų45.62%0.02325%0.254CS..THydrogen-bonded Turntrans-125.3-39.3-174.4-67.4-68.9-168-164.1-5.9113.8Y321 M322 T325 E670 L673 E677 W741Y321-R744 WeakPolarHBondContact CA-O 3.35Å; Y321-R744 HydrophobicContact CD1-CB 4.33Å; M322-R744 PolarHBondContact N-O 3.17Å; T325-R744 WeakPolarHBondContact CB-O 3.39Å; T325-R744 HydrophobicContact CG2-CB 4.31Å; T325-R744 WeakPolarHBondContact OG1-CA 3.29Å; T325-R744 PolarHBondContact OG1-O 3.25Å; T325-R744 VanDerWaalsContact OG1-O 3.11Å; E670-R744 IonicContact OE1-NH1 3.66Å; E670-R744 IonicContact OE2-CZ 3.96Å; E670-R744 VanDerWaalsContact OE2-CZ 3.25Å; E670-R744 IonicContact OE2-NH1 2.75Å; E670-R744 PolarHBondContact OE2-NH1 2.92Å; E670-R744 IonicContact OE2-NH2 3.61Å; E670-R744 PolarHBondContact OE2-NH2 2.82Å; L673-R744 HydrophobicContact CD2-CG 4.16Å; E677-R744 WeakPolarHBondContact OE1-CG 3.48Å; E677-R744 IonicContact OE1-NE 2.66Å; E677-R744 PolarHBondContact OE1-NE 2.79Å; W741-R744 PolarHBondContact O-N 2.96Å; W741-R744 VanDerWaalsContact O-N 3.08Å
745N95.1Very high94.3Very high9 Ų948.9 Ų48.95%0.04827%0.269CS..BIsolated β-bridgetrans-107.8161.6-165.7-58.8-63.2000112V320 Y321 W741V320-N745 CarbonylContact O-C 2.96Å; V320-N745 VanDerWaalsContact O-CA 3.25Å; V320-N745 WeakPolarHBondContact O-CA 3.43Å; V320-N745 WeakPolarHBondContact O-CB 3.44Å; Y321-N745 WeakPolarHBondContact CD1-OD1 3.24Å; Y321-N745 WeakPolarHBondContact CE1-OD1 2.92Å; W741-N745 HydrophobicContact CD2-CB 4.02Å; W741-N745 VanDerWaalsContact CE3-ND2 3.25Å; W741-N745 HydrophobicContact CG-CB 4.21Å; W741-N745 HydrophobicContact CZ2-CB 4.06Å; W741-N745 WeakPolarHBondContact O-CB 3.23Å; W741-N745 PolarHBondContact O-N 2.82Å; W741-N745 PolarHBondContact O-ND2 3.38Å
746L94.5Very high94Very high26 Ų2647.5 Ų47.514%0.13626%0.255CS..  trans-59.2129.8173.4-74.1169.6000110.5V320 M322 P356 F357 V748 T749V320-L746 HydrophobicContact CB-CD1 3.98Å; V320-L746 HydrophobicContact CG1-CD1 3.49Å; V320-L746 VanDerWaalsContact CG1-CD1 3.49Å; V320-L746 HydrophobicContact CG1-CG 4.35Å; V320-L746 PolarHBondContact O-N 3.25Å; M322-L746 HydrophobicContact SD-CB 4.44Å; M322-L746 HydrophobicContact SD-CD2 3.35Å; M322-L746 WeakPolarHBondContact SD-CD2 3.45Å; M322-L746 HydrophobicContact SD-CG 4Å; P356-L746 HydrophobicContact CB-CD1 3.82Å; F357-L746 HydrophobicContact CE1-CD1 4.3Å; L746-V748 PolarHBondContact O-N 2.71Å; L746-V748 VanDerWaalsContact O-N 3.11Å; L746-T749 HydrophobicContact CB-CG2 4.39Å; L746-T749 PolarHBondContact O-N 3.42Å; L746-T749 VanDerWaalsContact O-N 3.14Å; L746-T749 PolarHBondContact O-OG1 3.24Å
747P94.4Very high93.8Very high77 Ų7744 Ų4450%0.524%0.242SC..G310 helixtrans-58.5-28.6-179.9-28.135.4000114.3L742 T749 L750L742-P747 HydrophobicContact CD2-CB 3.82Å; L742-P747 HydrophobicContact CD2-CG 4.14Å; P747-T749 PolarHBondContact O-N 2.6Å; P747-L750 WeakPolarHBondContact O-CB 3.29Å; P747-L750 PolarHBondContact O-N 3.04Å
748V93Very high93.6Very high129 Ų12945.3 Ų45.378%0.78225%0.249SC*.G310 helixtrans-63.9-28.8-178.7-178.10000112L746L746-V748 PolarHBondContact O-N 2.71Å; L746-V748 VanDerWaalsContact O-N 3.11Å
749T92.4Very high93.3Very high21 Ų2145.3 Ų45.313%0.12925%0.252CS..G310 helixtrans-87.5-4.7-177.468.30000113.8C318 V320 W741 L746 P747 S751 D752 A753C318-T749 WeakPolarHBondContact O-CB 3.48Å; C318-T749 WeakPolarHBondContact O-CG2 3.34Å; C318-T749 PolarHBondContact O-OG1 3.18Å; V320-T749 HydrophobicContact CB-CG2 4.37Å; V320-T749 HydrophobicContact CG2-CG2 4.21Å; W741-T749 WeakPolarHBondContact CZ2-OG1 3.23Å; W741-T749 PolarHBondContact NE1-OG1 3.26Å; L746-T749 HydrophobicContact CB-CG2 4.39Å; L746-T749 PolarHBondContact O-N 3.42Å; L746-T749 VanDerWaalsContact O-N 3.14Å; L746-T749 PolarHBondContact O-OG1 3.24Å; P747-T749 PolarHBondContact O-N 2.6Å; T749-S751 PolarHBondContact O-N 3.49Å; T749-D752 PolarHBondContact O-N 3.14Å; T749-A753 PolarHBondContact O-N 3.29Å; T749-A753 VanDerWaalsContact O-N 3.11Å
750L94.3Very high93Very high19 Ų1939.2 Ų39.210%0.09922%0.224CC..Hα-helixtrans-59.9-43-177.7174.565.5000112.4Q738 W741 L742 P747 D752 A753 L754Q738-L750 HydrophobicContact CB-CD1 4.33Å; Q738-L750 HydrophobicContact CG-CD1 4.1Å; Q738-L750 HydrophobicContact CG-CD2 3.75Å; W741-L750 HydrophobicContact CB-CD1 4.1Å; W741-L750 HydrophobicContact CG-CD1 3.94Å; L742-L750 HydrophobicContact CD1-CD2 4.15Å; L742-L750 HydrophobicContact CD2-CD2 4.01Å; L742-L750 HydrophobicContact CG-CD2 4.14Å; P747-L750 WeakPolarHBondContact O-CB 3.29Å; P747-L750 PolarHBondContact O-N 3.04Å; L750-D752 VanDerWaalsContact C-N 3.3Å; L750-D752 PolarHBondContact O-N 3.31Å; L750-A753 PolarHBondContact O-N 2.87Å; L750-L754 HydrophobicContact CD1-CD1 3.99Å; L750-L754 HydrophobicContact CD1-CD2 4.41Å; L750-L754 HydrophobicContact CD1-CG 3.96Å; L750-L754 HydrophobicContact CD2-CD1 4.46Å; L750-L754 HydrophobicContact CG-CD1 3.9Å; L750-L754 HydrophobicContact CG-CG 4.29Å; L750-L754 WeakPolarHBondContact O-CG 3.39Å; L750-L754 PolarHBondContact O-N 2.86Å
751S92.3Very high92.9Very high82 Ų8239.3 Ų39.357%0.57322%0.222SC*.Hα-helixtrans-59.1-43.7-178.2-176.30000111.5T749 L754T749-S751 PolarHBondContact O-N 3.49Å; S751-L754 PolarHBondContact O-N 3.06Å
752D90.7Very high92.5Very high72 Ų7243 Ų4339%0.38524%0.235SC..Hα-helixtrans-68.2-38.5177.2-68.3-47000112.2C318 T749 L750 L754 K755C318-D752 HydrophobicContact CB-CB 4.32Å; T749-D752 PolarHBondContact O-N 3.14Å; L750-D752 VanDerWaalsContact C-N 3.3Å; L750-D752 PolarHBondContact O-N 3.31Å; D752-L754 VanDerWaalsContact C-N 3.29Å; D752-L754 PolarHBondContact O-N 3.3Å; D752-K755 WeakPolarHBondContact O-CB 3.4Å; D752-K755 PolarHBondContact O-N 3.4Å; D752-K755 WeakPolarHBondContact OD1-CE 3.21Å; D752-K755 IonicContact OD1-NZ 2.75Å; D752-K755 PolarHBondContact OD1-NZ 3.11Å
753A92.3Very high92.1Very high0 Ų041.3 Ų41.30%023%0.227CC..Hα-helixtrans-64.5-32176.400000113.1C318 E534 F737 W741 T749 L750 K755C318-A753 HydrophobicContact CB-CB 4.29Å; E534-A753 HydrophobicContact CB-CB 4.03Å; E534-A753 HydrophobicContact CG-CB 4.31Å; F737-A753 HydrophobicContact CE1-CB 4.13Å; F737-A753 HydrophobicContact CZ-CB 4.22Å; W741-A753 HydrophobicContact CD2-CB 4.09Å; W741-A753 HydrophobicContact CE3-CB 4.23Å; W741-A753 HydrophobicContact CH2-CB 3.7Å; W741-A753 HydrophobicContact CZ2-CB 3.56Å; W741-A753 HydrophobicContact CZ3-CB 4.05Å; T749-A753 PolarHBondContact O-N 3.29Å; T749-A753 VanDerWaalsContact O-N 3.11Å; L750-A753 PolarHBondContact O-N 2.87Å; A753-K755 VanDerWaalsContact C-N 3.33Å; A753-K755 PolarHBondContact O-N 3.35Å
754L93.6Very high91.8Very high14 Ų1439.3 Ų39.37%0.07321%0.213CC..Hα-helixtrans-74.2-19.9178.9-71.4173.7000113.6R734 F737 L750 S751 D752 M756 F757 D758R734-L754 HydrophobicContact CG-CD2 3.72Å; F737-L754 HydrophobicContact CD1-CD2 3.94Å; F737-L754 HydrophobicContact CE1-CD2 4.26Å; L750-L754 HydrophobicContact CD1-CD1 3.99Å; L750-L754 HydrophobicContact CD1-CD2 4.41Å; L750-L754 HydrophobicContact CD1-CG 3.96Å; L750-L754 HydrophobicContact CD2-CD1 4.46Å; L750-L754 HydrophobicContact CG-CD1 3.9Å; L750-L754 HydrophobicContact CG-CG 4.29Å; L750-L754 WeakPolarHBondContact O-CG 3.39Å; L750-L754 PolarHBondContact O-N 2.86Å; S751-L754 PolarHBondContact O-N 3.06Å; D752-L754 VanDerWaalsContact C-N 3.29Å; D752-L754 PolarHBondContact O-N 3.3Å; L754-M756 PolarHBondContact O-N 3.27Å; L754-F757 HydrophobicContact CD2-CD2 4.39Å; L754-F757 WeakPolarHBondContact O-CA 3.22Å; L754-F757 WeakPolarHBondContact O-CB 3.42Å; L754-F757 PolarHBondContact O-N 3.4Å; L754-D758 VanDerWaalsContact O-CG 3.29Å; L754-D758 PolarHBondContact O-N 3Å
755K90.8Very high91.4Very high108 Ų10840.3 Ų40.347%0.4722%0.218SC..Hα-helixtrans-53.8-34.3-178.5-73.8175.9175164.80113.8D752 A753 D758 N759D752-K755 WeakPolarHBondContact O-CB 3.4Å; D752-K755 PolarHBondContact O-N 3.4Å; D752-K755 WeakPolarHBondContact OD1-CE 3.21Å; D752-K755 IonicContact OD1-NZ 2.75Å; D752-K755 PolarHBondContact OD1-NZ 3.11Å; A753-K755 VanDerWaalsContact C-N 3.33Å; A753-K755 PolarHBondContact O-N 3.35Å; K755-D758 PolarHBondContact O-N 2.74Å; K755-N759 VanDerWaalsContact O-CB 3.23Å; K755-N759 WeakPolarHBondContact O-CB 3.14Å; K755-N759 PolarHBondContact O-N 3.23Å; K755-N759 PolarHBondContact O-ND2 2.83Å; K755-N759 VanDerWaalsContact O-ND2 3.12Å
756M90.1Very high90.7Very high16 Ų1641.6 Ų41.68%0.07923%0.228CC..Hα-helixtrans-61.3-46.7175.1170.8176.137.700111.7C533 E534 I535 L615 L616 L754 D758 L760C533-M756 HydrophobicContact CB-SD 4.45Å; C533-M756 PolarHBondContact SG-SD 3.03Å; E534-M756 HydrophobicContact CB-CE 4.27Å; I535-M756 HydrophobicContact CB-CE 4.21Å; L615-M756 HydrophobicContact CB-SD 4.48Å; L616-M756 HydrophobicContact CD2-SD 4.38Å; L754-M756 PolarHBondContact O-N 3.27Å; M756-D758 VanDerWaalsContact C-N 3.35Å; M756-L760 WeakPolarHBondContact O-CB 3.36Å; M756-L760 PolarHBondContact O-N 2.83Å; M756-L760 VanDerWaalsContact O-N 3.11Å
757F92.8Very high89.8Confident0 Ų044.6 Ų44.60%025%0.248CC..Hα-helixtrans-64.9-43.1177-66.5-91.9000110.7I535 M684 L730 I733 R734 F737 L754 L760 F761I535-F757 HydrophobicContact CD1-CZ 4.05Å; I535-F757 HydrophobicContact CG1-CZ 4.34Å; M684-F757 HydrophobicContact CE-CD1 4.13Å; M684-F757 HydrophobicContact CE-CE1 3.85Å; M684-F757 HydrophobicContact CE-CZ 4.45Å; M684-F757 HydrophobicContact SD-CE1 4.39Å; L730-F757 HydrophobicContact CD1-CD1 3.66Å; L730-F757 HydrophobicContact CD1-CE1 4.3Å; L730-F757 HydrophobicContact CG-CD1 4.47Å; I733-F757 HydrophobicContact CG2-CE1 3.91Å; R734-F757 HydrophobicContact CB-CB 4.29Å; R734-F757 HydrophobicContact CB-CD1 3.9Å; R734-F757 HydrophobicContact CB-CG 4.18Å; R734-F757 HydrophobicContact CG-CB 3.94Å; R734-F757 HydrophobicContact CG-CD1 4.33Å; R734-F757 HydrophobicContact CG-CG 4.09Å; F737-F757 HydrophobicContact CB-CE2 4.34Å; F737-F757 HydrophobicContact CB-CZ 3.97Å; F737-F757 HydrophobicContact CD1-CD2 4.18Å; F737-F757 AromaticContact CD1-CE2 3.46Å; F737-F757 HydrophobicContact CD1-CE2 3.46Å; F737-F757 VanDerWaalsContact CD1-CE2 3.46Å; F737-F757 AromaticContact CD1-CZ 3.98Å; F737-F757 HydrophobicContact CD1-CZ 3.98Å; F737-F757 HydrophobicContact CD2-CE2 4.25Å; F737-F757 HydrophobicContact CD2-CZ 4.19Å; F737-F757 HydrophobicContact CE1-CD2 4.4Å; F737-F757 AromaticContact CE1-CE2 3.71Å; F737-F757 HydrophobicContact CE1-CE2 3.71Å; F737-F757 HydrophobicContact CE2-CE2 4.47Å; F737-F757 AromaticContact CG-CE2 3.74Å; F737-F757 HydrophobicContact CG-CE2 3.74Å; F737-F757 AromaticContact CG-CZ 3.76Å; F737-F757 HydrophobicContact CG-CZ 3.76Å; F737-F757 HydrophobicContact CZ-CE2 4.21Å; L754-F757 HydrophobicContact CD2-CD2 4.39Å; L754-F757 WeakPolarHBondContact O-CA 3.22Å; L754-F757 WeakPolarHBondContact O-CB 3.42Å; L754-F757 PolarHBondContact O-N 3.4Å; F757-L760 PolarHBondContact O-N 3.21Å; F757-F761 VanDerWaalsContact O-CB 3.27Å; F757-F761 WeakPolarHBondContact O-CB 3.14Å; F757-F761 PolarHBondContact O-N 3.45Å
758D91.3Very high89.1Confident36 Ų3645.9 Ų45.919%0.19326%0.259CS..Hα-helixtrans-66.2-41.6-177.5-60.1-17.7000111.4R734 L754 K755 M756 F761 R762 L777R734-D758 IonicContact CZ-OD1 3.68Å; R734-D758 IonicContact NE-OD1 3.01Å; R734-D758 PolarHBondContact NE-OD1 3.36Å; R734-D758 IonicContact NH2-OD1 3.36Å; R734-D758 PolarHBondContact NH2-OD1 2.63Å; R734-D758 VanDerWaalsContact NH2-OD1 3.09Å; R734-D758 IonicContact NH2-OD2 3.24Å; L754-D758 VanDerWaalsContact O-CG 3.29Å; L754-D758 PolarHBondContact O-N 3Å; K755-D758 PolarHBondContact O-N 2.74Å; M756-D758 VanDerWaalsContact C-N 3.35Å; D758-F761 PolarHBondContact O-N 2.99Å; D758-R762 WeakPolarHBondContact O-CB 3.32Å; D758-R762 PolarHBondContact O-N 2.8Å; D758-L777 HydrophobicContact CB-CD1 3.71Å
759N89.8Confident88.6Confident70 Ų7043.7 Ų43.737%0.37424%0.243SC..Hα-helixtrans-63.4-45.9175-75.3-30.2000111.8K755 R762 N763K755-N759 VanDerWaalsContact O-CB 3.23Å; K755-N759 WeakPolarHBondContact O-CB 3.14Å; K755-N759 PolarHBondContact O-N 3.23Å; K755-N759 PolarHBondContact O-ND2 2.83Å; K755-N759 VanDerWaalsContact O-ND2 3.12Å; N759-R762 PolarHBondContact O-N 3.06Å; N759-R762 PolarHBondContact OD1-NH2 3.4Å; N759-N763 VanDerWaalsContact O-CG 3.29Å; N759-N763 PolarHBondContact O-N 3.19Å; N759-N763 VanDerWaalsContact O-N 3.08Å; N759-N763 PolarHBondContact O-OD1 3.23Å
760L90.4Very high88Confident4 Ų445.2 Ų45.22%0.02125%0.248CC..Hα-helixtrans-65.9-39.2177.5-177.361.6000111.5L615 P618 M684 L687 L691 L730 M756 F757 N763 L764L615-L760 HydrophobicContact CD2-CD2 4.28Å; P618-L760 HydrophobicContact CG-CD1 4.03Å; M684-L760 HydrophobicContact CE-CD2 4.01Å; L687-L760 HydrophobicContact CD2-CD2 4.29Å; L691-L760 HydrophobicContact CD2-CD1 4.21Å; L730-L760 HydrophobicContact CD1-CD2 3.95Å; L730-L760 HydrophobicContact CD2-CB 3.96Å; L730-L760 HydrophobicContact CD2-CD2 4Å; L730-L760 HydrophobicContact CD2-CG 3.83Å; M756-L760 WeakPolarHBondContact O-CB 3.36Å; M756-L760 PolarHBondContact O-N 2.83Å; M756-L760 VanDerWaalsContact O-N 3.11Å; F757-L760 PolarHBondContact O-N 3.21Å; L760-N763 PolarHBondContact O-N 3.1Å; L760-L764 HydrophobicContact CG-CD1 4.46Å; L760-L764 WeakPolarHBondContact O-CG 3.49Å; L760-L764 PolarHBondContact O-N 2.87Å; L760-L764 VanDerWaalsContact O-N 3.13Å
761F91.7Very high87.3Confident14 Ų1447.6 Ų47.66%0.06127%0.271CS..Hα-helixtrans-61.7-45.7175.8-177.7-101.5000111.4A727 L730 L731 F757 D758 N763 L764 L765 L777A727-F761 HydrophobicContact CB-CD2 4.05Å; A727-F761 HydrophobicContact CB-CE2 3.82Å; L730-F761 HydrophobicContact CD2-CB 3.81Å; L730-F761 HydrophobicContact CD2-CD2 4.5Å; L731-F761 HydrophobicContact CD1-CD2 4.43Å; L731-F761 HydrophobicContact CD1-CE2 3.58Å; L731-F761 HydrophobicContact CD1-CZ 4Å; L731-F761 HydrophobicContact CD2-CD2 3.9Å; L731-F761 HydrophobicContact CD2-CE2 3.77Å; L731-F761 HydrophobicContact CD2-CG 4.49Å; L731-F761 HydrophobicContact CD2-CZ 4.23Å; L731-F761 HydrophobicContact CG-CD2 3.95Å; L731-F761 HydrophobicContact CG-CE2 3.59Å; L731-F761 HydrophobicContact CG-CZ 4.34Å; F757-F761 VanDerWaalsContact O-CB 3.27Å; F757-F761 WeakPolarHBondContact O-CB 3.14Å; F757-F761 PolarHBondContact O-N 3.45Å; D758-F761 PolarHBondContact O-N 2.99Å; F761-N763 VanDerWaalsContact C-N 3.31Å; F761-N763 PolarHBondContact O-N 2.97Å; F761-L764 WeakPolarHBondContact O-CB 3.38Å; F761-L764 PolarHBondContact O-N 2.79Å; F761-L764 VanDerWaalsContact O-N 3.08Å; F761-L765 HydrophobicContact CD1-CD1 4.02Å; F761-L765 HydrophobicContact CD1-CG 4.38Å; F761-L765 HydrophobicContact CE1-CD1 3.63Å; F761-L765 HydrophobicContact CE1-CD2 4.38Å; F761-L765 HydrophobicContact CE1-CG 4.12Å; F761-L765 HydrophobicContact CZ-CD1 4.31Å; F761-L765 HydrophobicContact CZ-CD2 4.25Å; F761-L765 HydrophobicContact CZ-CG 4.45Å; F761-L765 PolarHBondContact O-N 2.85Å; F761-L777 HydrophobicContact CB-CD1 4.44Å; F761-L777 HydrophobicContact CD1-CD1 3.7Å; F761-L777 HydrophobicContact CD1-CD2 4.03Å; F761-L777 HydrophobicContact CD1-CG 4.01Å; F761-L777 HydrophobicContact CE1-CD1 4.36Å; F761-L777 HydrophobicContact CE1-CD2 4.3Å; F761-L777 HydrophobicContact CE1-CG 4.24Å; F761-L777 HydrophobicContact CG-CD1 4.39Å; F761-L777 HydrophobicContact CG-CD2 4.37Å
762R88.2Confident86.7Confident83 Ų8349.7 Ų49.731%0.31327%0.27SS..Hα-helixtrans-59.8-40.9175.9-174.417859.6-153.3-11.6112D758 N759 L764 L765 Q770 E774D758-R762 WeakPolarHBondContact O-CB 3.32Å; D758-R762 PolarHBondContact O-N 2.8Å; N759-R762 PolarHBondContact O-N 3.06Å; N759-R762 PolarHBondContact OD1-NH2 3.4Å; R762-L764 PolarHBondContact O-N 2.86Å; R762-L765 PolarHBondContact O-N 2.98Å; R762-L765 VanDerWaalsContact O-N 3.13Å; R762-Q770 HydrophobicContact CG-CB 3.92Å; R762-Q770 HydrophobicContact CG-CG 3.8Å; R762-Q770 PolarHBondContact O-NE2 3.35Å; R762-E774 IonicContact NH1-OE1 3.9Å
763N86.8Confident85.9Confident37 Ų3746.4 Ų46.420%0.19825%0.253CS..Hα-helixtrans-65.3-27.5177-69.7-9.3000112.8V715 N759 L760 F761V715-N763 VanDerWaalsContact CG1-O 3.24Å; V715-N763 WeakPolarHBondContact CG1-O 3.32Å; N759-N763 VanDerWaalsContact O-CG 3.29Å; N759-N763 PolarHBondContact O-N 3.19Å; N759-N763 VanDerWaalsContact O-N 3.08Å; N759-N763 PolarHBondContact O-OD1 3.23Å; L760-N763 PolarHBondContact O-N 3.1Å; F761-N763 VanDerWaalsContact C-N 3.31Å; F761-N763 PolarHBondContact O-N 2.97Å
764L88.7Confident85.1Confident3 Ų352.1 Ų52.12%0.01628%0.28CS..Hα-helixtrans-79.2-20.8174.9-67.9166.5000112.7V715 R723 L726 A727 L730 L760 F761 R762V715-L764 HydrophobicContact CG1-CD2 3.75Å; V715-L764 HydrophobicContact CG1-CG 4.47Å; R723-L764 WeakPolarHBondContact CB-O 3.34Å; R723-L764 WeakPolarHBondContact CD-O 3.33Å; L726-L764 HydrophobicContact CB-CD1 4.03Å; L726-L764 HydrophobicContact CB-CD2 3.93Å; L726-L764 HydrophobicContact CD1-CD2 3.99Å; A727-L764 HydrophobicContact CB-CB 4.25Å; A727-L764 HydrophobicContact CB-CD1 4.37Å; L730-L764 HydrophobicContact CD2-CD1 4.03Å; L760-L764 HydrophobicContact CG-CD1 4.46Å; L760-L764 WeakPolarHBondContact O-CG 3.49Å; L760-L764 PolarHBondContact O-N 2.87Å; L760-L764 VanDerWaalsContact O-N 3.13Å; F761-L764 WeakPolarHBondContact O-CB 3.38Å; F761-L764 PolarHBondContact O-N 2.79Å; F761-L764 VanDerWaalsContact O-N 3.08Å; R762-L764 PolarHBondContact O-N 2.86Å
765L85.7Confident84.3Confident26 Ų2658.2 Ų58.214%0.13631%0.313CS..SBendtrans-78.3145.8177.8-68.6178.8000112.2F761 R762 L769 Q770F761-L765 HydrophobicContact CD1-CD1 4.02Å; F761-L765 HydrophobicContact CD1-CG 4.38Å; F761-L765 HydrophobicContact CE1-CD1 3.63Å; F761-L765 HydrophobicContact CE1-CD2 4.38Å; F761-L765 HydrophobicContact CE1-CG 4.12Å; F761-L765 HydrophobicContact CZ-CD1 4.31Å; F761-L765 HydrophobicContact CZ-CD2 4.25Å; F761-L765 HydrophobicContact CZ-CG 4.45Å; F761-L765 PolarHBondContact O-N 2.85Å; R762-L765 PolarHBondContact O-N 2.98Å; R762-L765 VanDerWaalsContact O-N 3.13Å; L765-L769 HydrophobicContact CB-CB 4.5Å; L765-Q770 HydrophobicContact CB-CG 4.17Å; L765-Q770 PolarHBondContact O-NE2 2.66Å
766P80Confident83.5Confident37 Ų3758 Ų5824%0.2432%0.316CS..  trans-55.2145.7167.1-20.930.9000111.3S768 L769 Q770P766-S768 PolarHBondContact O-N 2.96Å; P766-L769 HydrophobicContact CG-CD1 4.17Å; P766-L769 PolarHBondContact O-N 2.83Å; P766-Q770 PolarHBondContact O-N 3.37Å
767P76.7Confident82.9Confident88 Ų8860.7 Ų60.757%0.57133%0.33SS*.THydrogen-bonded Turntrans-51.6-33.6-179.8-2934.6000114.2L769P767-L769 VanDerWaalsContact C-N 3.29Å; P767-L769 PolarHBondContact O-N 3.46Å
768S80.4Confident82.4Confident104 Ų10463.7 Ų63.773%0.72735%0.347SS*.THydrogen-bonded Turntrans-68.6-21.6176.954.50000114.7P766P766-S768 PolarHBondContact O-N 2.96Å
769L81.8Confident82Confident83 Ų8365.2 Ų65.244%0.43536%0.355SS..THydrogen-bonded Turntrans-106.2-6.5-178-66.7-179.1000113.3L765 P766 P767 A771 F772 G773L765-L769 HydrophobicContact CB-CB 4.5Å; P766-L769 HydrophobicContact CG-CD1 4.17Å; P766-L769 PolarHBondContact O-N 2.83Å; P767-L769 VanDerWaalsContact C-N 3.29Å; P767-L769 PolarHBondContact O-N 3.46Å; L769-A771 VanDerWaalsContact C-N 3.3Å; L769-A771 PolarHBondContact O-N 2.91Å; L769-F772 WeakPolarHBondContact O-CB 3.48Å; L769-F772 PolarHBondContact O-N 3.45Å; L769-G773 PolarHBondContact O-N 3.14Å
770Q80Confident81.5Confident53 Ų5364.9 Ų64.925%0.24835%0.354CS..Hα-helixtrans-58.5-41.9-178-72.7-178.8-5.400112.1R762 L765 P766 F772 G773 E774R762-Q770 HydrophobicContact CG-CB 3.92Å; R762-Q770 HydrophobicContact CG-CG 3.8Å; R762-Q770 PolarHBondContact O-NE2 3.35Å; L765-Q770 HydrophobicContact CB-CG 4.17Å; L765-Q770 PolarHBondContact O-NE2 2.66Å; P766-Q770 PolarHBondContact O-N 3.37Å; Q770-F772 VanDerWaalsContact C-N 3.3Å; Q770-F772 PolarHBondContact O-N 3.37Å; Q770-G773 PolarHBondContact O-N 3.21Å; Q770-E774 PolarHBondContact O-N 3.17Å
771A79.4Confident81Confident70 Ų7068.5 Ų68.558%0.57937%0.374SS*.Hα-helixtrans-66.7-29.2175.400000113.5L769L769-A771 VanDerWaalsContact C-N 3.3Å; L769-A771 PolarHBondContact O-N 2.91Å
772F79.2Confident80.3Confident125 Ų12571.9 Ų71.955%0.54839%0.393SS..Hα-helixtrans-75.2-36.3174.7-177.4-100.7000111.4L769 Q770 E774 N775 L776L769-F772 WeakPolarHBondContact O-CB 3.48Å; L769-F772 PolarHBondContact O-N 3.45Å; Q770-F772 VanDerWaalsContact C-N 3.3Å; Q770-F772 PolarHBondContact O-N 3.37Å; F772-E774 VanDerWaalsContact C-N 3.28Å; F772-E774 PolarHBondContact O-N 3.37Å; F772-N775 PolarHBondContact O-N 2.86Å; F772-N775 VanDerWaalsContact O-N 3.16Å; F772-L776 HydrophobicContact CD1-CD1 4.11Å; F772-L776 HydrophobicContact CE1-CD1 3.41Å; F772-L776 VanDerWaalsContact CE1-CD1 3.41Å; F772-L776 HydrophobicContact CZ-CD1 4.07Å; F772-L776 PolarHBondContact O-N 3.03Å
773G74.4Confident79.8Confident4 Ų471.1 Ų71.14%0.04140%0.398CS..Hα-helixtrans-59.1-36.3175.800000113.3L769 Q770 N775 L776 L777L769-G773 PolarHBondContact O-N 3.14Å; Q770-G773 PolarHBondContact O-N 3.21Å; G773-N775 VanDerWaalsContact C-N 3.27Å; G773-N775 PolarHBondContact O-N 2.59Å; G773-L776 PolarHBondContact O-N 2.83Å; G773-L776 VanDerWaalsContact O-N 3.08Å; G773-L777 PolarHBondContact O-N 3.1Å
774E74.6Confident79.3Confident120 Ų12073.6 Ų73.656%0.56141%0.413SS*.Hα-helixtrans-62.2-31.9176-72.1-176.817100113.3R762 Q770 F772 L776R762-E774 IonicContact NH1-OE1 3.9Å; Q770-E774 PolarHBondContact O-N 3.17Å; F772-E774 VanDerWaalsContact C-N 3.28Å; F772-E774 PolarHBondContact O-N 3.37Å; E774-L776 VanDerWaalsContact C-N 3.32Å
775N77.2Confident78.6Confident142 Ų14279 Ų7976%0.75944%0.443SS*.Hα-helixtrans-81-13.9176.4-68-46.7000113.3F772 G773F772-N775 PolarHBondContact O-N 2.86Å; F772-N775 VanDerWaalsContact O-N 3.16Å; G773-N775 VanDerWaalsContact C-N 3.27Å; G773-N775 PolarHBondContact O-N 2.59Å
776L74.4Confident78Confident102 Ų10283.4 Ų83.453%0.53447%0.469SS..Hα-helixtrans-97.2-29.4-171.8-157.2143.6000112.4F772 G773 E774F772-L776 HydrophobicContact CD1-CD1 4.11Å; F772-L776 HydrophobicContact CE1-CD1 3.41Å; F772-L776 VanDerWaalsContact CE1-CD1 3.41Å; F772-L776 HydrophobicContact CZ-CD1 4.07Å; F772-L776 PolarHBondContact O-N 3.03Å; G773-L776 PolarHBondContact O-N 2.83Å; G773-L776 VanDerWaalsContact O-N 3.08Å; E774-L776 VanDerWaalsContact C-N 3.32Å
777L78.2Confident77.8Confident73 Ų7387.6 Ų87.638%0.38249%0.49SS..  trans-80.50177.7-71.3172.5000112.7L731 R734 D758 F761 G773L731-L777 HydrophobicContact CD2-CD2 3.78Å; R734-L777 PolarHBondContact NH2-O 3.16Å; D758-L777 HydrophobicContact CB-CD1 3.71Å; F761-L777 HydrophobicContact CB-CD1 4.44Å; F761-L777 HydrophobicContact CD1-CD1 3.7Å; F761-L777 HydrophobicContact CD1-CD2 4.03Å; F761-L777 HydrophobicContact CD1-CG 4.01Å; F761-L777 HydrophobicContact CE1-CD1 4.36Å; F761-L777 HydrophobicContact CE1-CD2 4.3Å; F761-L777 HydrophobicContact CE1-CG 4.24Å; F761-L777 HydrophobicContact CG-CD1 4.39Å; F761-L777 HydrophobicContact CG-CD2 4.37Å; G773-L777 PolarHBondContact O-N 3.1Å

Retrieved 777 of 777 residues in 223.4 ms (Link to these results)