A0A077Z9B8_TRITR Loading...

asparaginase

AlphaFold DB , UniProt , Accession A0A077Z9B8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 616 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M28.4Very low58.7Low231 Ų23189.5 Ų89.5100%1.13851%0.514SS*.  0124.10-70.7175.6-16800107.4I3M1-I3 VanDerWaalsContact C-N 3.34Å; M1-I3 PolarHBondContact O-N 3.3Å
2S23.4Very low62Low123 Ų12382 Ų8286%0.8647%0.471SS*.  trans-66.1100.6168.459.60000107.2S4S2-S4 PolarHBondContact O-N 3.44Å; S2-S4 VanDerWaalsContact O-N 3.07Å
3I29.9Very low64.8Low130 Ų13075.7 Ų75.767%0.66744%0.435SS*.  trans-55.9116170.5-59.8168.7000104.9M1M1-I3 VanDerWaalsContact C-N 3.34Å; M1-I3 PolarHBondContact O-N 3.3Å
4S29.3Very low67.2Low92 Ų9270.3 Ų70.364%0.64340%0.404SS*.  trans-47.8132.7173.155.70000107.6S2 G6S2-S4 PolarHBondContact O-N 3.44Å; S2-S4 VanDerWaalsContact O-N 3.07Å; S4-G6 PolarHBondContact O-N 2.94Å
5P37.5Very low69.3Low128 Ų12865.6 Ų65.683%0.83138%0.377SS*.  trans-50.7112.7178.319.6-29.8000107.4K7P5-K7 PolarHBondContact O-N 3.05Å
6G55.5Low71.1Confident40 Ų4061.5 Ų61.541%0.41235%0.353SS..  trans-56.5143.4-171.200000109S4 L8S4-G6 PolarHBondContact O-N 2.94Å; G6-L8 PolarHBondContact O-N 2.96Å; G6-L8 VanDerWaalsContact O-N 3.09Å
7K71.9Confident72.6Confident79 Ų7958 Ų5834%0.34333%0.333SS..  trans-56.3122.5176.6-58.6176.6-166.6163.40108P5 E9 H56 N487P5-K7 PolarHBondContact O-N 3.05Å; K7-E9 HydrophobicContact CB-CG 3.82Å; K7-E9 WeakPolarHBondContact CD-OE1 3.4Å; K7-E9 PolarHBondContact O-N 2.94Å; K7-H56 PolarHBondContact NZ-ND1 3.38Å; K7-N487 PolarHBondContact O-ND2 3.16Å
8L87.8Confident74Confident53 Ų5354.8 Ų54.828%0.27732%0.315SS..  trans-76.795.3176.2-65-178.1000107.9G6 N73 R74 R75 N485 N487G6-L8 PolarHBondContact O-N 2.96Å; G6-L8 VanDerWaalsContact O-N 3.09Å; L8-N73 WeakPolarHBondContact CB-O 3.34Å; L8-R74 HydrophobicContact CB-CG 4.36Å; L8-R74 CarbonylContact O-C 3.58Å; L8-R74 VanDerWaalsContact O-CA 3.27Å; L8-R74 WeakPolarHBondContact O-CA 3.38Å; L8-R75 PolarHBondContact O-N 3.13Å; L8-N485 VanDerWaalsContact CD2-O 3.25Å; L8-N485 WeakPolarHBondContact CD2-O 3.11Å; L8-N487 WeakPolarHBondContact CD2-OD1 3.41Å
9E91.8Very high75.1Confident14 Ų1451.9 Ų51.97%0.06530%0.299CS..EExtended strand (participates in β ladder)trans-122.7154.8-174.8-69.6-176.5-179.900110.4K7 Y52 Y57 R74 R75 L77K7-E9 HydrophobicContact CB-CG 3.82Å; K7-E9 WeakPolarHBondContact CD-OE1 3.4Å; K7-E9 PolarHBondContact O-N 2.94Å; E9-Y52 PolarHBondContact OE1-OH 2.53Å; E9-Y57 PolarHBondContact OE1-OH 2.87Å; E9-Y57 PolarHBondContact OE2-OH 3.03Å; E9-R74 PolarHBondContact O-NH1 3.18Å; E9-R75 CarbonylContact C-O 3.5Å; E9-R75 WeakPolarHBondContact CA-O 3.39Å; E9-R75 HydrophobicContact CG-CB 4.29Å; E9-L77 HydrophobicContact CB-CD1 3.75Å; E9-L77 HydrophobicContact CG-CD1 3.64Å; E9-L77 WeakPolarHBondContact OE2-CD2 3.44Å
10S94.5Very high76.1Confident2 Ų251 Ų511%0.01429%0.294CS..EExtended strand (participates in β ladder)trans-134136.6172.1-173.30000109.4R75 L77 D112 G169S10-R75 PolarHBondContact N-O 3.45Å; S10-L77 PolarHBondContact O-N 3.43Å; S10-D112 WeakPolarHBondContact CA-OD2 2.9Å; S10-D112 WeakPolarHBondContact OG-CB 3.46Å; S10-D112 PolarHBondContact OG-OD2 3.15Å; S10-G169 WeakPolarHBondContact CB-O 2.93Å; S10-G169 VanDerWaalsContact OG-CA 3.23Å; S10-G169 WeakPolarHBondContact OG-CA 3.35Å; S10-G169 PolarHBondContact OG-O 2.78Å
11K95.6Very high77.1Confident92 Ų9248.5 Ų48.540%0.428%0.28SS..EExtended strand (participates in β ladder)trans-103.8120.2-178.1-65.7-174.7-179.6-1740110.1L77 Y111 D112K11-L77 CarbonylContact C-O 3.57Å; K11-L77 WeakPolarHBondContact CA-O 3.41Å; K11-Y111 HydrophobicContact CB-CD1 4.01Å; K11-Y111 CarbonylContact O-C 3.28Å; K11-Y111 WeakPolarHBondContact O-CA 3.46Å; K11-D112 PolarHBondContact N-OD2 3.11Å; K11-D112 PolarHBondContact O-N 3.05Å
12V98.2Very high80.2Confident0 Ų037.5 Ų37.50%023%0.225CC..EExtended strand (participates in β ladder)trans-116.5133.2178.7176.40000110.3V14 V76 L77 Y78 R79 Y111 G113 V115 L165 A168V12-V14 HydrophobicContact CG1-CG2 4.47Å; V12-V76 HydrophobicContact CB-CG1 4.22Å; V12-V76 HydrophobicContact CG2-CG1 3.76Å; V12-L77 PolarHBondContact N-O 2.59Å; V12-Y78 WeakPolarHBondContact O-CA 3.48Å; V12-Y78 WeakPolarHBondContact O-CB 3.32Å; V12-R79 PolarHBondContact O-N 3.14Å; V12-R79 VanDerWaalsContact O-N 3.1Å; V12-Y111 VanDerWaalsContact C-CD1 3.48Å; V12-G113 WeakPolarHBondContact CA-O 3.39Å; V12-V115 HydrophobicContact CG1-CB 4.43Å; V12-V115 HydrophobicContact CG1-CG2 3.79Å; V12-L165 HydrophobicContact CB-CD2 4.37Å; V12-L165 HydrophobicContact CG1-CD2 3.96Å; V12-A168 HydrophobicContact CG1-CB 3.82Å; V12-A168 HydrophobicContact CG2-CB 3.94Å
13L98.3Very high83.6Confident0 Ų032.1 Ų32.10%019%0.187CC..EExtended strand (participates in β ladder)trans-93.4125.7171.3-179.662.5000109.5L15 I81 C107 Y111 G113 F114 V115L13-L15 HydrophobicContact CD1-CD2 4.34Å; L13-L15 HydrophobicContact CD2-CD2 3.9Å; L13-L15 HydrophobicContact CG-CD2 3.9Å; L13-L15 HydrophobicContact CG-CG 4.43Å; L13-I81 HydrophobicContact CD1-CD1 3.68Å; L13-I81 HydrophobicContact CD1-CG1 3.89Å; L13-C107 HydrophobicContact CD2-CB 3.9Å; L13-Y111 HydrophobicContact CB-CD1 3.72Å; L13-Y111 HydrophobicContact CB-CD2 3.86Å; L13-Y111 HydrophobicContact CB-CE1 3.88Å; L13-Y111 HydrophobicContact CB-CE2 4.04Å; L13-Y111 HydrophobicContact CB-CG 3.69Å; L13-Y111 HydrophobicContact CD1-CE1 4.26Å; L13-Y111 HydrophobicContact CD1-CE2 4.19Å; L13-Y111 HydrophobicContact CD2-CD2 4.27Å; L13-Y111 HydrophobicContact CD2-CE2 4.13Å; L13-Y111 HydrophobicContact CG-CE2 4.36Å; L13-G113 PolarHBondContact N-O 3.04Å; L13-G113 VanDerWaalsContact N-O 3.09Å; L13-F114 HydrophobicContact CB-CD1 3.85Å; L13-F114 HydrophobicContact CB-CE1 4.16Å; L13-F114 HydrophobicContact CD2-CD1 4.11Å; L13-F114 HydrophobicContact CD2-CE1 4.18Å; L13-F114 HydrophobicContact CG-CD1 4.45Å; L13-F114 CarbonylContact O-C 3.55Å; L13-F114 WeakPolarHBondContact O-CA 3.44Å; L13-V115 PolarHBondContact O-N 2.84Å
14V98.5Very high86.5Confident0 Ų029.2 Ų29.20%017%0.17CC..EExtended strand (participates in β ladder)trans-105.3116.6175.5-174.20000108.9V12 Y78 R79 L80 I81 V115 L117 L165V12-V14 HydrophobicContact CG1-CG2 4.47Å; V14-Y78 HydrophobicContact CG2-CD2 3.64Å; V14-Y78 HydrophobicContact CG2-CG 4.19Å; V14-R79 PolarHBondContact N-O 3.32Å; V14-L80 HydrophobicContact CB-CB 4.35Å; V14-L80 HydrophobicContact CB-CG 4.39Å; V14-L80 HydrophobicContact CG1-CD1 4.28Å; V14-L80 HydrophobicContact CG1-CG 4.27Å; V14-L80 CarbonylContact O-C 3.51Å; V14-L80 WeakPolarHBondContact O-CA 3.31Å; V14-I81 PolarHBondContact O-N 3.34Å; V14-V115 CarbonylContact C-O 3.56Å; V14-V115 VanDerWaalsContact CA-O 3.3Å; V14-V115 WeakPolarHBondContact CA-O 3.45Å; V14-V115 HydrophobicContact CG1-CB 4.42Å; V14-V115 HydrophobicContact CG1-CG1 4.34Å; V14-V115 HydrophobicContact CG2-CB 4.19Å; V14-L117 HydrophobicContact CG1-CD1 3.82Å; V14-L117 HydrophobicContact CG1-CG 3.82Å; V14-L165 HydrophobicContact CG2-CD2 3.85Å
15L98.4Very high89.4Confident0 Ų027.5 Ų27.50%016%0.158CC..EExtended strand (participates in β ladder)trans-97.5114.7173.5-57.2-177.3000108.8L13 I81 Y83 I100 N103 I104 V115 I116 L117L13-L15 HydrophobicContact CD1-CD2 4.34Å; L13-L15 HydrophobicContact CD2-CD2 3.9Å; L13-L15 HydrophobicContact CG-CD2 3.9Å; L13-L15 HydrophobicContact CG-CG 4.43Å; L15-I81 HydrophobicContact CD2-CB 4.06Å; L15-I81 HydrophobicContact CD2-CD1 4.38Å; L15-Y83 HydrophobicContact CB-CE1 4.23Å; L15-Y83 HydrophobicContact CD2-CE1 4.29Å; L15-I100 HydrophobicContact CD1-CG2 4.18Å; L15-N103 HydrophobicContact CD1-CB 4.27Å; L15-I104 HydrophobicContact CD1-CD1 4.22Å; L15-I104 HydrophobicContact CD1-CG1 3.69Å; L15-V115 PolarHBondContact N-O 3.47Å; L15-I116 CarbonylContact O-C 3.58Å; L15-I116 WeakPolarHBondContact O-CA 3.44Å; L15-L117 PolarHBondContact O-N 2.93Å
16Y97.9Very high91.8Very high0 Ų025.9 Ų25.90%014%0.14CC..EExtended strand (participates in β ladder)trans-97.3103.3177.3177.3-142.2000110.5G18 I21 G22 L37 I81 E82 Y83 L86 L117Y16-G18 VanDerWaalsContact CE2-CA 3.44Å; Y16-G18 VanDerWaalsContact CE2-O 3.3Å; Y16-G18 WeakPolarHBondContact CE2-O 3.41Å; Y16-I21 HydrophobicContact CE2-CG2 4.2Å; Y16-G22 VanDerWaalsContact OH-CA 3.23Å; Y16-G22 WeakPolarHBondContact OH-CA 3.13Å; Y16-G22 PolarHBondContact OH-O 2.82Å; Y16-L37 HydrophobicContact CD1-CB 4.13Å; Y16-L37 HydrophobicContact CD1-CD2 3.66Å; Y16-L37 HydrophobicContact CD1-CG 4.45Å; Y16-L37 HydrophobicContact CD2-CD2 3.66Å; Y16-L37 HydrophobicContact CE1-CB 3.68Å; Y16-L37 HydrophobicContact CE1-CD2 3.69Å; Y16-L37 HydrophobicContact CE1-CG 4.32Å; Y16-L37 HydrophobicContact CE2-CD2 3.65Å; Y16-L37 HydrophobicContact CG-CD2 3.7Å; Y16-I81 PolarHBondContact N-O 3.38Å; Y16-E82 HydrophobicContact CD1-CB 4.38Å; Y16-E82 HydrophobicContact CD1-CG 3.72Å; Y16-E82 HydrophobicContact CE1-CG 4.25Å; Y16-Y83 WeakPolarHBondContact O-CB 3.43Å; Y16-Y83 PolarHBondContact O-N 3.21Å; Y16-L86 HydrophobicContact CD1-CD1 4.44Å; Y16-L86 HydrophobicContact CD1-CD2 3.69Å; Y16-L86 HydrophobicContact CD2-CD2 4.34Å; Y16-L86 HydrophobicContact CE1-CD1 3.56Å; Y16-L86 HydrophobicContact CE1-CD2 3.49Å; Y16-L86 VanDerWaalsContact CE1-CD2 3.49Å; Y16-L86 HydrophobicContact CE1-CG 4.19Å; Y16-L86 HydrophobicContact CE2-CD2 4.2Å; Y16-L86 HydrophobicContact CG-CD2 4.09Å; Y16-L117 HydrophobicContact CD2-CB 3.78Å; Y16-L117 HydrophobicContact CD2-CD1 4.3Å
17T97.8Very high93.3Very high2 Ų231.6 Ų31.61%0.01216%0.161CC..EExtended strand (participates in β ladder)trans-93.1-15.8-175.964.50000113.2Y83 L87 M92 I100 I116 L117T17-Y83 HydrophobicContact CG2-CD2 4.08Å; T17-Y83 HydrophobicContact CG2-CE2 4.02Å; T17-Y83 HydrophobicContact CG2-CG 4.49Å; T17-L87 PolarHBondContact O-N 3.47Å; T17-M92 HydrophobicContact CG2-CE 4.41Å; T17-M92 VanDerWaalsContact OG1-CE 3.22Å; T17-M92 WeakPolarHBondContact OG1-CE 3.1Å; T17-I100 HydrophobicContact CG2-CD1 3.85Å; T17-I100 HydrophobicContact CG2-CG1 3.99Å; T17-I116 HydrophobicContact CG2-CG2 3.92Å; T17-L117 PolarHBondContact N-O 2.92Å; T17-L117 PolarHBondContact OG1-O 2.96Å
18G96.4Very high93.9Very high0 Ų037.5 Ų37.50%019%0.186CC..EExtended strand (participates in β ladder)trans126.8-151.8-17600000112.3Y16 L87Y16-G18 VanDerWaalsContact CE2-CA 3.44Å; Y16-G18 VanDerWaalsContact CE2-O 3.3Å; Y16-G18 WeakPolarHBondContact CE2-O 3.41Å; G18-L87 CarbonylContact C-O 3.51Å; G18-L87 VanDerWaalsContact CA-O 3.31Å; G18-L87 WeakPolarHBondContact CA-O 2.97Å
19G95.7Very high93.9Very high1 Ų139.2 Ų39.21%0.0120%0.199CC..SBendtrans83.9168.7-174.100000115.3I21 G22 L87G19-I21 PolarHBondContact O-N 2.69Å; G19-G22 PolarHBondContact O-N 3.34Å; G19-L87 PolarHBondContact N-O 3.05Å
20T95.6Very high93.7Very high32 Ų3243 Ų4320%0.19621%0.213CC..G310 helixtrans-51.9-33.2-171.1-48.40000114.1G22 M23 S146 Q147 P149T20-G22 PolarHBondContact O-N 3.23Å; T20-M23 PolarHBondContact O-N 2.79Å; T20-S146 WeakPolarHBondContact CB-O 3.34Å; T20-Q147 WeakPolarHBondContact CG2-O 3.35Å; T20-P149 HydrophobicContact CG2-CG 3.92Å; T20-P149 VanDerWaalsContact O-CA 3.25Å; T20-P149 WeakPolarHBondContact O-CA 3.36Å; T20-P149 VanDerWaalsContact O-CB 3.29Å; T20-P149 WeakPolarHBondContact O-CB 3.13Å; T20-P149 WeakPolarHBondContact O-CG 3.27Å
21I95.8Very high93.4Very high0 Ų045.1 Ų45.10%023%0.226CC..G310 helixtrans-52.1-35.1-177.6-166.4169.9000114.3Y16 G19 L37 L117 S146 I150Y16-I21 HydrophobicContact CE2-CG2 4.2Å; G19-I21 PolarHBondContact O-N 2.69Å; I21-L37 HydrophobicContact CG2-CD2 4.45Å; I21-L117 HydrophobicContact CD1-CD2 3.84Å; I21-L117 HydrophobicContact CG2-CB 4.31Å; I21-S146 WeakPolarHBondContact CA-OG 3.25Å; I21-S146 WeakPolarHBondContact CB-OG 3.48Å; I21-S146 PolarHBondContact N-OG 3.47Å; I21-I150 HydrophobicContact CG1-CB 4.3Å; I21-I150 WeakPolarHBondContact O-CB 3.49Å; I21-I150 WeakPolarHBondContact O-CG2 3.39Å; I21-I150 PolarHBondContact O-N 3.19Å
22G95.2Very high93.1Very high0 Ų042.8 Ų42.80%022%0.221CC..G310 helixtrans-116.616.4177.400000114.2Y16 G19 T20 Y36Y16-G22 VanDerWaalsContact OH-CA 3.23Å; Y16-G22 WeakPolarHBondContact OH-CA 3.13Å; Y16-G22 PolarHBondContact OH-O 2.82Å; G19-G22 PolarHBondContact O-N 3.34Å; T20-G22 PolarHBondContact O-N 3.23Å; G22-Y36 WeakPolarHBondContact O-CD1 3.41Å
23M94Very high92.8Very high10 Ų1044.2 Ų44.25%0.04923%0.229CC..EExtended strand (participates in β ladder)trans-74.9151.2175.1-71-176173.300111.6T20 Y30 V31 P32 P149T20-M23 PolarHBondContact O-N 2.79Å; M23-Y30 HydrophobicContact CB-CD1 4.32Å; M23-V31 VanDerWaalsContact CA-O 3.25Å; M23-V31 WeakPolarHBondContact CA-O 3.25Å; M23-V31 WeakPolarHBondContact CB-O 3.44Å; M23-P32 HydrophobicContact CE-CG 3.95Å; M23-P149 WeakPolarHBondContact O-CB 3.45Å
24Q91.3Very high92.5Very high68 Ų6846.5 Ų46.532%0.31825%0.248SC..EExtended strand (participates in β ladder)trans-116.4142.1171.8-168.9-179.212.900109.4Q26 V31 V33 Y36Q24-Q26 PolarHBondContact O-N 2.99Å; Q24-V31 PolarHBondContact N-O 3.13Å; Q24-V31 PolarHBondContact O-N 3.39Å; Q24-V31 VanDerWaalsContact O-N 3.08Å; Q24-V33 HydrophobicContact CB-CB 4.33Å; Q24-V33 HydrophobicContact CB-CG2 3.67Å; Q24-Y36 HydrophobicContact CB-CD1 4.26Å; Q24-Y36 HydrophobicContact CB-CE1 4.05Å; Q24-Y36 HydrophobicContact CB-CE2 4.49Å; Q24-Y36 HydrophobicContact CG-CE1 4.38Å; Q24-Y36 HydrophobicContact CG-CE2 4.14Å
25S88.7Confident92.1Very high57 Ų5751.1 Ų51.140%0.39927%0.273SS..EExtended strand (participates in β ladder)trans-71.1115.6172.9-170.60000109.8V29S25-V29 WeakPolarHBondContact CA-O 3.41Å
26Q88.4Confident91.9Very high94 Ų9453.9 Ų53.944%0.43928%0.284SS..EExtended strand (participates in β ladder)trans-121.6123.6169.4-61.5-173.113.100107.8Q24 K28 V29 V31 V33Q24-Q26 PolarHBondContact O-N 2.99Å; Q26-K28 PolarHBondContact O-N 3.27Å; Q26-V29 PolarHBondContact N-O 3.23Å; Q26-V29 PolarHBondContact O-N 2.75Å; Q26-V31 HydrophobicContact CB-CG2 4.07Å; Q26-V31 HydrophobicContact CG-CG2 3.84Å; Q26-V33 VanDerWaalsContact NE2-CG2 3.29Å
27N87.1Confident91.7Very high160 Ų16053.9 Ų53.986%0.85628%0.284SS*.THydrogen-bonded Turntrans52.237.9-176.7-59.8-35.3000114.2V29N27-V29 PolarHBondContact O-N 2.92Å
28K85Confident91.4Very high202 Ų20254.3 Ų54.388%0.87829%0.286SS*.THydrogen-bonded Turntrans66.315.3-177.3-50.5178.1179.21780115Q26Q26-K28 PolarHBondContact O-N 3.27Å
29V86.8Confident91.2Very high90 Ų9058.2 Ų58.255%0.54531%0.307SS..EExtended strand (participates in β ladder)trans-119.2135.3171.9-176.50000108.5S25 Q26 N27 V31S25-V29 WeakPolarHBondContact CA-O 3.41Å; Q26-V29 PolarHBondContact N-O 3.23Å; Q26-V29 PolarHBondContact O-N 2.75Å; N27-V29 PolarHBondContact O-N 2.92Å; V29-V31 HydrophobicContact CG1-CG1 4.36Å
30Y89.1Confident91.1Very high93 Ų9359.5 Ų59.537%0.36532%0.317SS..EExtended strand (participates in β ladder)trans-79.9125.6174.2-73.3-70.7000109.6M23 P149 E152M23-Y30 HydrophobicContact CB-CD1 4.32Å; Y30-P149 HydrophobicContact CD1-CG 3.66Å; Y30-P149 HydrophobicContact CE1-CG 3.56Å; Y30-P149 HydrophobicContact CG-CG 4.31Å; Y30-E152 PolarHBondContact OH-OE1 2.84Å
31V87.7Confident91Very high46 Ų4658 Ų5828%0.27931%0.308SS..EExtended strand (participates in β ladder)trans-129.8149.5178.3-63.80000110.2M23 Q24 Q26 V29 V33M23-V31 VanDerWaalsContact CA-O 3.25Å; M23-V31 WeakPolarHBondContact CA-O 3.25Å; M23-V31 WeakPolarHBondContact CB-O 3.44Å; Q24-V31 PolarHBondContact N-O 3.13Å; Q24-V31 PolarHBondContact O-N 3.39Å; Q24-V31 VanDerWaalsContact O-N 3.08Å; Q26-V31 HydrophobicContact CB-CG2 4.07Å; Q26-V31 HydrophobicContact CG-CG2 3.84Å; V29-V31 HydrophobicContact CG1-CG1 4.36Å; V31-V33 HydrophobicContact CG2-CG2 4.14Å; V31-V33 PolarHBondContact O-N 2.78Å
32P89.8Confident90.8Very high44 Ų4461.6 Ų61.629%0.28632%0.321SS..EExtended strand (participates in β ladder)trans-63.1132.5171.7-17.931.5000110.3M23 L86M23-P32 HydrophobicContact CE-CG 3.95Å; P32-L86 HydrophobicContact CB-CB 3.58Å; P32-L86 HydrophobicContact CB-CD1 4.25Å
33V90.7Very high90.6Very high30 Ų3066.9 Ų66.918%0.18235%0.35CS..  trans-127.6121.8178.9-179.10000109.3Q24 Q26 V31 Y36Q24-V33 HydrophobicContact CB-CB 4.33Å; Q24-V33 HydrophobicContact CB-CG2 3.67Å; Q26-V33 VanDerWaalsContact NE2-CG2 3.29Å; V31-V33 HydrophobicContact CG2-CG2 4.14Å; V31-V33 PolarHBondContact O-N 2.78Å; V33-Y36 WeakPolarHBondContact O-CB 3.48Å; V33-Y36 PolarHBondContact O-N 3.16Å
34A91.9Very high90.6Very high48 Ų4868 Ų6840%0.39736%0.356SS..THydrogen-bonded Turntrans-60.6142.6-179.500000112Y36 E82A34-Y36 PolarHBondContact O-N 3.33Å; A34-E82 WeakPolarHBondContact CA-OE1 3.41Å
35N91.6Very high90.7Very high97 Ų9772.9 Ų72.952%0.51938%0.379SS..THydrogen-bonded Turntrans59.91.6-178.4-58.5-73.6000115.9N39 E82N35-N39 WeakPolarHBondContact O-CB 3.41Å; N35-N39 VanDerWaalsContact O-CG 3.29Å; N35-N39 PolarHBondContact O-N 3.24Å; N35-N39 PolarHBondContact O-ND2 2.69Å; N35-E82 VanDerWaalsContact N-CD 3.34Å; N35-E82 PolarHBondContact N-OE1 3.44Å; N35-E82 PolarHBondContact N-OE2 3.1Å
36Y92.8Very high90.9Very high58 Ų5872.5 Ų72.523%0.22738%0.376CS..Hα-helixtrans-69.4-50.7-177.6179.8-111.3000111.7G22 Q24 V33 A34 L38 N39 A40 S151G22-Y36 WeakPolarHBondContact O-CD1 3.41Å; Q24-Y36 HydrophobicContact CB-CD1 4.26Å; Q24-Y36 HydrophobicContact CB-CE1 4.05Å; Q24-Y36 HydrophobicContact CB-CE2 4.49Å; Q24-Y36 HydrophobicContact CG-CE1 4.38Å; Q24-Y36 HydrophobicContact CG-CE2 4.14Å; V33-Y36 WeakPolarHBondContact O-CB 3.48Å; V33-Y36 PolarHBondContact O-N 3.16Å; A34-Y36 PolarHBondContact O-N 3.33Å; Y36-L38 PolarHBondContact O-N 3.24Å; Y36-N39 PolarHBondContact O-N 2.67Å; Y36-A40 PolarHBondContact O-N 2.98Å; Y36-S151 WeakPolarHBondContact CE1-OG 3.22Å; Y36-S151 WeakPolarHBondContact OH-CB 3.48Å; Y36-S151 PolarHBondContact OH-OG 2.85Å
37L93.8Very high91.2Very high0 Ų068 Ų680%036%0.355CS..Hα-helixtrans-63.2-44.8-177179.460.1000112.1Y16 I21 N39 A40 I41 L117 I150Y16-L37 HydrophobicContact CD1-CB 4.13Å; Y16-L37 HydrophobicContact CD1-CD2 3.66Å; Y16-L37 HydrophobicContact CD1-CG 4.45Å; Y16-L37 HydrophobicContact CD2-CD2 3.66Å; Y16-L37 HydrophobicContact CE1-CB 3.68Å; Y16-L37 HydrophobicContact CE1-CD2 3.69Å; Y16-L37 HydrophobicContact CE1-CG 4.32Å; Y16-L37 HydrophobicContact CE2-CD2 3.65Å; Y16-L37 HydrophobicContact CG-CD2 3.7Å; I21-L37 HydrophobicContact CG2-CD2 4.45Å; L37-N39 VanDerWaalsContact C-N 3.29Å; L37-N39 PolarHBondContact O-N 2.94Å; L37-A40 WeakPolarHBondContact O-CB 3.47Å; L37-A40 PolarHBondContact O-N 2.83Å; L37-I41 HydrophobicContact CD1-CD1 3.89Å; L37-I41 HydrophobicContact CD1-CG1 4.07Å; L37-I41 HydrophobicContact CD2-CD1 4.4Å; L37-I41 HydrophobicContact CG-CD1 3.81Å; L37-I41 HydrophobicContact CG-CG1 4.38Å; L37-I41 WeakPolarHBondContact O-CG1 3.43Å; L37-I41 PolarHBondContact O-N 2.99Å; L37-L117 HydrophobicContact CD2-CD1 3.63Å; L37-I150 HydrophobicContact CD1-CB 4.42Å; L37-I150 HydrophobicContact CD1-CG2 3.43Å; L37-I150 VanDerWaalsContact CD1-CG2 3.43Å
38L91.8Very high91.7Very high11 Ų1160.9 Ų60.96%0.05832%0.317CS..Hα-helixtrans-60-41.3179.2-179.559.3000111.5Y36 R42 L80Y36-L38 PolarHBondContact O-N 3.24Å; L38-R42 HydrophobicContact CD1-CG 4.34Å; L38-R42 WeakPolarHBondContact O-CB 3.28Å; L38-R42 VanDerWaalsContact O-CG 3.31Å; L38-R42 WeakPolarHBondContact O-CG 3.43Å; L38-R42 PolarHBondContact O-N 3.27Å; L38-L80 HydrophobicContact CB-CD2 4.46Å; L38-L80 HydrophobicContact CD1-CB 4.2Å; L38-L80 HydrophobicContact CD1-CD2 4.44Å
39N92.2Very high92.2Very high82 Ų8252.9 Ų52.944%0.43928%0.284SS..Hα-helixtrans-67.5-38.9176.3-73.8-29.5000112.3N35 Y36 L37 N43N35-N39 WeakPolarHBondContact O-CB 3.41Å; N35-N39 VanDerWaalsContact O-CG 3.29Å; N35-N39 PolarHBondContact O-N 3.24Å; N35-N39 PolarHBondContact O-ND2 2.69Å; Y36-N39 PolarHBondContact O-N 2.67Å; L37-N39 VanDerWaalsContact C-N 3.29Å; L37-N39 PolarHBondContact O-N 2.94Å; N39-N43 PolarHBondContact O-N 3.04Å; N39-N43 PolarHBondContact O-ND2 3.3Å
40A92.9Very high92.5Very high28 Ų2853.1 Ų53.123%0.23128%0.277CS..Hα-helixtrans-62-49.3174.500000111.4Y36 L37 R42 N43 D44 I150Y36-A40 PolarHBondContact O-N 2.98Å; L37-A40 WeakPolarHBondContact O-CB 3.47Å; L37-A40 PolarHBondContact O-N 2.83Å; A40-R42 PolarHBondContact O-N 2.83Å; A40-N43 PolarHBondContact O-N 2.94Å; A40-D44 PolarHBondContact O-N 2.91Å; A40-D44 VanDerWaalsContact O-N 3.1Å; A40-I150 HydrophobicContact CB-CG2 4.28Å
41I94.1Very high92.8Very high0 Ų052.4 Ų52.40%029%0.286CS..Hα-helixtrans-60.2-47.1178.1-71.2172000111.3L37 N43 D44 L47 N48 Y78 L80 L161L37-I41 HydrophobicContact CD1-CD1 3.89Å; L37-I41 HydrophobicContact CD1-CG1 4.07Å; L37-I41 HydrophobicContact CD2-CD1 4.4Å; L37-I41 HydrophobicContact CG-CD1 3.81Å; L37-I41 HydrophobicContact CG-CG1 4.38Å; L37-I41 WeakPolarHBondContact O-CG1 3.43Å; L37-I41 PolarHBondContact O-N 2.99Å; I41-N43 PolarHBondContact O-N 3.39Å; I41-N43 VanDerWaalsContact O-N 3.17Å; I41-D44 PolarHBondContact O-N 3.21Å; I41-D44 VanDerWaalsContact O-N 3.14Å; I41-L47 HydrophobicContact CG1-CD1 4.13Å; I41-L47 HydrophobicContact CG2-CB 4.13Å; I41-N48 WeakPolarHBondContact O-CB 3.47Å; I41-Y78 HydrophobicContact CG2-CE2 4.23Å; I41-Y78 WeakPolarHBondContact CG2-OH 3.27Å; I41-L80 HydrophobicContact CD1-CD1 3.65Å; I41-L161 HydrophobicContact CD1-CD2 3.9Å; I41-L161 HydrophobicContact CG1-CD2 4.35Å
42R92.2Very high93.1Very high75 Ų7552.2 Ų52.228%0.28328%0.281SS..Hα-helixtrans-59.1-30.6-179.3-83.1177.1165.5163.6-1.7112.8L38 A40 N48 K50 N62L38-R42 HydrophobicContact CD1-CG 4.34Å; L38-R42 WeakPolarHBondContact O-CB 3.28Å; L38-R42 VanDerWaalsContact O-CG 3.31Å; L38-R42 WeakPolarHBondContact O-CG 3.43Å; L38-R42 PolarHBondContact O-N 3.27Å; A40-R42 PolarHBondContact O-N 2.83Å; R42-N48 PolarHBondContact O-ND2 3.14Å; R42-N48 VanDerWaalsContact O-ND2 3.07Å; R42-K50 WeakPolarHBondContact O-CE 3.12Å; R42-K50 PolarHBondContact O-NZ 2.85Å; R42-N62 VanDerWaalsContact NH2-CA 3.25Å; R42-N62 VanDerWaalsContact NH2-N 3.18Å; R42-N62 PolarHBondContact NH2-OD1 2.59Å
43N91.6Very high93.2Very high112 Ų11251.2 Ų51.260%0.59927%0.273SS*.Hα-helixtrans-93.6-10.9-178.4-69.3-37.8000114N39 A40 I41 K50N39-N43 PolarHBondContact O-N 3.04Å; N39-N43 PolarHBondContact O-ND2 3.3Å; A40-N43 PolarHBondContact O-N 2.94Å; I41-N43 PolarHBondContact O-N 3.39Å; I41-N43 VanDerWaalsContact O-N 3.17Å; N43-K50 PolarHBondContact OD1-NZ 2.99Å
44D92.8Very high93.3Very high33 Ų3356.3 Ų56.318%0.17630%0.295CS..  trans-86.2111.7174.7-168.4-32.3000110.5A40 I41 S46 L47 N48 R158A40-D44 PolarHBondContact O-N 2.91Å; A40-D44 VanDerWaalsContact O-N 3.1Å; I41-D44 PolarHBondContact O-N 3.21Å; I41-D44 VanDerWaalsContact O-N 3.14Å; D44-S46 VanDerWaalsContact CG-OG 3.27Å; D44-S46 PolarHBondContact O-N 3.32Å; D44-S46 VanDerWaalsContact OD1-CB 3.31Å; D44-S46 WeakPolarHBondContact OD1-CB 3.25Å; D44-S46 PolarHBondContact OD1-N 3.32Å; D44-S46 PolarHBondContact OD1-OG 2.98Å; D44-S46 PolarHBondContact OD2-OG 3.32Å; D44-L47 HydrophobicContact CB-CB 4.28Å; D44-L47 HydrophobicContact CB-CD1 4.08Å; D44-L47 HydrophobicContact CB-CG 4.27Å; D44-L47 PolarHBondContact O-N 3.42Å; D44-N48 PolarHBondContact O-N 3.23Å; D44-R158 IonicContact OD2-CZ 3.65Å; D44-R158 IonicContact OD2-NE 2.72Å; D44-R158 PolarHBondContact OD2-NE 3.17Å; D44-R158 IonicContact OD2-NH2 3.23Å; D44-R158 PolarHBondContact OD2-NH2 3.01Å
45Q93.7Very high93.3Very high170 Ų17061.8 Ų61.879%0.79431%0.309SS*.THydrogen-bonded Turntrans-62.8-22.5180-66.3-179.5-5.100113.4L47 P67Q45-L47 VanDerWaalsContact C-N 3.28Å; Q45-P67 WeakPolarHBondContact O-CG 3.39Å
46S93.2Very high93.2Very high49 Ų4960.1 Ų60.134%0.34330%0.298SS..THydrogen-bonded Turntrans-76.9-16.9175.871.80000113D44 L66 P67 R158D44-S46 VanDerWaalsContact CG-OG 3.27Å; D44-S46 PolarHBondContact O-N 3.32Å; D44-S46 VanDerWaalsContact OD1-CB 3.31Å; D44-S46 WeakPolarHBondContact OD1-CB 3.25Å; D44-S46 PolarHBondContact OD1-N 3.32Å; D44-S46 PolarHBondContact OD1-OG 2.98Å; D44-S46 PolarHBondContact OD2-OG 3.32Å; S46-L66 WeakPolarHBondContact O-CD1 3.35Å; S46-P67 VanDerWaalsContact O-CD 3.28Å; S46-P67 WeakPolarHBondContact O-CD 3.44Å; S46-R158 VanDerWaalsContact OG-CD 3.31Å; S46-R158 WeakPolarHBondContact OG-CD 3.3Å; S46-R158 PolarHBondContact OG-NE 3.28Å
47L95.5Very high93.1Very high1 Ų158.6 Ų58.61%0.00529%0.292CS..THydrogen-bonded Turntrans-111.4-22-179.3-60.8174.6000112.6I41 D44 Q45 Y78 I150 R158 L161 V162I41-L47 HydrophobicContact CG1-CD1 4.13Å; I41-L47 HydrophobicContact CG2-CB 4.13Å; D44-L47 HydrophobicContact CB-CB 4.28Å; D44-L47 HydrophobicContact CB-CD1 4.08Å; D44-L47 HydrophobicContact CB-CG 4.27Å; D44-L47 PolarHBondContact O-N 3.42Å; Q45-L47 VanDerWaalsContact C-N 3.28Å; L47-Y78 WeakPolarHBondContact O-CE1 3.42Å; L47-Y78 PolarHBondContact O-OH 2.79Å; L47-I150 HydrophobicContact CD1-CD1 3.63Å; L47-R158 HydrophobicContact CD1-CG 4.49Å; L47-R158 HydrophobicContact CD2-CG 4.19Å; L47-R158 HydrophobicContact CG-CG 4.42Å; L47-L161 HydrophobicContact CD1-CD2 4.3Å; L47-L161 HydrophobicContact CD2-CD2 4.24Å; L47-L161 HydrophobicContact CD2-CG 4.5Å; L47-V162 HydrophobicContact CD2-CG2 3.46Å; L47-V162 VanDerWaalsContact CD2-CG2 3.46Å
48N96.2Very high92.6Very high9 Ų967.8 Ų67.85%0.04833%0.327CS..  trans-142.7110.9-174.7-171.741000113.6I41 R42 D44 K50 I53 C64 V65I41-N48 WeakPolarHBondContact O-CB 3.47Å; R42-N48 PolarHBondContact O-ND2 3.14Å; R42-N48 VanDerWaalsContact O-ND2 3.07Å; D44-N48 PolarHBondContact O-N 3.23Å; N48-K50 PolarHBondContact O-N 2.72Å; N48-I53 WeakPolarHBondContact OD1-CD1 3.34Å; N48-C64 WeakPolarHBondContact OD1-CA 3.28Å; N48-V65 CarbonylContact C-O 3.49Å; N48-V65 WeakPolarHBondContact CA-O 3.47Å; N48-V65 PolarHBondContact OD1-N 2.69Å
49D96.1Very high92.3Very high34 Ų3476.2 Ų76.218%0.18236%0.364CS..  trans-87.289.1172.9-172.7-16.6000110.9S51 Y52 I53 V65 R75D49-S51 PolarHBondContact O-N 3.45Å; D49-S51 PolarHBondContact OD1-N 3.08Å; D49-S51 PolarHBondContact OD1-OG 2.91Å; D49-Y52 PolarHBondContact O-N 3.15Å; D49-Y52 PolarHBondContact OD1-N 2.85Å; D49-Y52 VanDerWaalsContact OD1-N 3.1Å; D49-I53 PolarHBondContact O-N 3.23Å; D49-V65 PolarHBondContact N-O 3.29Å; D49-R75 VanDerWaalsContact CG-NH2 3.25Å; D49-R75 IonicContact OD2-CZ 3.99Å; D49-R75 IonicContact OD2-NH1 3.53Å; D49-R75 PolarHBondContact OD2-NH1 3.33Å; D49-R75 IonicContact OD2-NH2 2.91Å; D49-R75 PolarHBondContact OD2-NH2 3.31Å
50K93.6Very high91.9Very high95 Ų9575.7 Ų75.741%0.41336%0.359SS..Hα-helixtrans-58.1-36.5178.4-63.3-177-178.7-178.20112.5R42 N43 N48 Y52 I53 E54R42-K50 WeakPolarHBondContact O-CE 3.12Å; R42-K50 PolarHBondContact O-NZ 2.85Å; N43-K50 PolarHBondContact OD1-NZ 2.99Å; N48-K50 PolarHBondContact O-N 2.72Å; K50-Y52 VanDerWaalsContact C-N 3.31Å; K50-Y52 PolarHBondContact O-N 3.44Å; K50-I53 PolarHBondContact O-N 2.85Å; K50-E54 WeakPolarHBondContact O-CG 3.43Å; K50-E54 PolarHBondContact O-N 3.38Å
51S94.1Very high91.4Very high79 Ų7981.8 Ų81.855%0.55238%0.382SS*.Hα-helixtrans-64.7-37.8-177.6770000111.9D49 K55D49-S51 PolarHBondContact O-N 3.45Å; D49-S51 PolarHBondContact OD1-N 3.08Å; D49-S51 PolarHBondContact OD1-OG 2.91Å; S51-K55 WeakPolarHBondContact O-CB 3.36Å; S51-K55 PolarHBondContact O-N 2.97Å
52Y94.1Very high90.9Very high42 Ų4284.8 Ų84.817%0.16540%0.398CS..Hα-helixtrans-68.1-42.6176-165.5-92.2000111.8E9 D49 K50 K55 H56 Y57 V65 R75E9-Y52 PolarHBondContact OE1-OH 2.53Å; D49-Y52 PolarHBondContact O-N 3.15Å; D49-Y52 PolarHBondContact OD1-N 2.85Å; D49-Y52 VanDerWaalsContact OD1-N 3.1Å; K50-Y52 VanDerWaalsContact C-N 3.31Å; K50-Y52 PolarHBondContact O-N 3.44Å; Y52-K55 PolarHBondContact O-N 2.88Å; Y52-H56 AromaticContact CD2-CD2 3.82Å; Y52-H56 AromaticContact CE1-CD2 3.8Å; Y52-H56 AromaticContact CE2-CD2 3.58Å; Y52-H56 AromaticContact CE2-NE2 3.91Å; Y52-H56 AromaticContact CZ-CD2 3.57Å; Y52-H56 WeakPolarHBondContact O-CB 3.5Å; Y52-H56 PolarHBondContact O-N 2.84Å; Y52-H56 VanDerWaalsContact O-N 3.09Å; Y52-Y57 HydrophobicContact CD1-CE2 4.5Å; Y52-Y57 HydrophobicContact CE1-CD2 4.44Å; Y52-Y57 AromaticContact CE1-CE2 3.97Å; Y52-Y57 HydrophobicContact CE1-CE2 3.97Å; Y52-V65 HydrophobicContact CD1-CB 4.46Å; Y52-V65 HydrophobicContact CD1-CG1 3.81Å; Y52-V65 HydrophobicContact CD1-CG2 4.3Å; Y52-V65 HydrophobicContact CE1-CG1 4.34Å; Y52-V65 HydrophobicContact CG-CG1 4.38Å; Y52-R75 HydrophobicContact CE1-CG 4.34Å
53I92.9Very high91Very high23 Ų2381.9 Ų81.912%0.11839%0.388CS..Hα-helixtrans-63.1-49.1177.6-65.9169.1000110.7N48 D49 K50 K55 H56 Y57 R58 V65N48-I53 WeakPolarHBondContact OD1-CD1 3.34Å; D49-I53 PolarHBondContact O-N 3.23Å; K50-I53 PolarHBondContact O-N 2.85Å; I53-K55 PolarHBondContact O-N 3.28Å; I53-H56 PolarHBondContact O-N 3.23Å; I53-Y57 CarbonylContact O-C 3.54Å; I53-Y57 WeakPolarHBondContact O-CA 3.39Å; I53-Y57 PolarHBondContact O-N 2.67Å; I53-R58 PolarHBondContact O-N 2.83Å; I53-R58 VanDerWaalsContact O-N 3.12Å; I53-V65 HydrophobicContact CD1-CB 4.31Å; I53-V65 HydrophobicContact CD1-CG2 3.94Å; I53-V65 HydrophobicContact CG1-CB 4.08Å; I53-V65 HydrophobicContact CG1-CG2 3.46Å; I53-V65 VanDerWaalsContact CG1-CG2 3.46Å
54E92.6Very high91.2Very high136 Ų13676.5 Ų76.564%0.63636%0.36SS*.Hα-helixtrans-58.2-35.1179.9-74.4170.8-17100112.4K50K50-E54 WeakPolarHBondContact O-CG 3.43Å; K50-E54 PolarHBondContact O-N 3.38Å
55K92.3Very high91.4Very high163 Ų16375 Ų7571%0.70935%0.351SS*.Hα-helixtrans-76.9-32.2179.8-171.4179.1177.1-1780113.8S51 Y52 I53S51-K55 WeakPolarHBondContact O-CB 3.36Å; S51-K55 PolarHBondContact O-N 2.97Å; Y52-K55 PolarHBondContact O-N 2.88Å; I53-K55 PolarHBondContact O-N 3.28Å
56H89.3Confident91.6Very high62 Ų6267 Ų6729%0.28731%0.314SS..Hα-helixtrans-123.9-26.6-165.6-65.7-46.4000115.2K7 Y52 I53K7-H56 PolarHBondContact NZ-ND1 3.38Å; Y52-H56 AromaticContact CD2-CD2 3.82Å; Y52-H56 AromaticContact CE1-CD2 3.8Å; Y52-H56 AromaticContact CE2-CD2 3.58Å; Y52-H56 AromaticContact CE2-NE2 3.91Å; Y52-H56 AromaticContact CZ-CD2 3.57Å; Y52-H56 WeakPolarHBondContact O-CB 3.5Å; Y52-H56 PolarHBondContact O-N 2.84Å; Y52-H56 VanDerWaalsContact O-N 3.09Å; I53-H56 PolarHBondContact O-N 3.23Å
57Y89.9Confident91.7Very high26 Ų2666.2 Ų66.210%0.10231%0.308CS..  trans-139.633.3-168.8-60.6-68.3000112E9 Y52 I53 F59 E60 L63 L77E9-Y57 PolarHBondContact OE1-OH 2.87Å; E9-Y57 PolarHBondContact OE2-OH 3.03Å; Y52-Y57 HydrophobicContact CD1-CE2 4.5Å; Y52-Y57 HydrophobicContact CE1-CD2 4.44Å; Y52-Y57 AromaticContact CE1-CE2 3.97Å; Y52-Y57 HydrophobicContact CE1-CE2 3.97Å; I53-Y57 CarbonylContact O-C 3.54Å; I53-Y57 WeakPolarHBondContact O-CA 3.39Å; I53-Y57 PolarHBondContact O-N 2.67Å; Y57-F59 PolarHBondContact O-N 3.23Å; Y57-E60 HydrophobicContact CD1-CG 4.29Å; Y57-E60 WeakPolarHBondContact CD1-OE1 3.29Å; Y57-E60 PolarHBondContact O-N 2.82Å; Y57-L63 VanDerWaalsContact CB-CD2 3.47Å; Y57-L63 HydrophobicContact CD1-CD2 4.19Å; Y57-L63 HydrophobicContact CD2-CD2 4.01Å; Y57-L63 HydrophobicContact CG-CD2 3.61Å; Y57-L77 HydrophobicContact CD2-CD2 4.12Å; Y57-L77 HydrophobicContact CE1-CD2 4.27Å; Y57-L77 HydrophobicContact CE2-CD2 3.53Å; Y57-L77 HydrophobicContact CE2-CG 4.5Å
58R84.5Confident91.6Very high194 Ų19470.9 Ų70.973%0.73234%0.338SS*.THydrogen-bonded Turntrans-50.7-30.6-172.8-174.8176.8177.6-177.2-0114.5I53I53-R58 PolarHBondContact O-N 2.83Å; I53-R58 VanDerWaalsContact O-N 3.12Å
59F84.6Confident91.5Very high187 Ų18772.6 Ų72.682%0.8235%0.349SS*.THydrogen-bonded Turntrans-102.24-176.1-53.7-68.1000113.7Y57Y57-F59 PolarHBondContact O-N 3.23Å
60E83.6Confident91.2Very high72 Ų7281.7 Ų81.734%0.33638%0.381SS..  trans-88110.9178.3-68.7-154.4-158.700111.9Y57 L63 R79Y57-E60 HydrophobicContact CD1-CG 4.29Å; Y57-E60 WeakPolarHBondContact CD1-OE1 3.29Å; Y57-E60 PolarHBondContact O-N 2.82Å; E60-L63 HydrophobicContact CB-CB 4Å; E60-L63 HydrophobicContact CB-CD2 3.97Å; E60-R79 IonicContact OE2-NH2 3.35Å
61E82.7Confident90.9Very high155 Ų15580.3 Ų80.372%0.72439%0.393SS*.THydrogen-bonded Turntrans-71.6147.9174.4-63.3-175176.300112L63E61-L63 PolarHBondContact O-N 3.47Å
62N84.7Confident90.8Very high63 Ų6377.9 Ų77.934%0.33737%0.373SS..THydrogen-bonded Turntrans56.514.6176.6-58.1-25.6000115.5R42 R79R42-N62 VanDerWaalsContact NH2-CA 3.25Å; R42-N62 VanDerWaalsContact NH2-N 3.18Å; R42-N62 PolarHBondContact NH2-OD1 2.59Å; N62-R79 HydrophobicContact CB-CG 4.41Å; N62-R79 WeakPolarHBondContact O-CA 3.43Å
63L93.9Very high90.3Very high14 Ų1479.5 Ų79.57%0.07339%0.385CS..EExtended strand (participates in β ladder)trans-82.4132.9169.9-171.871.3000110Y57 E60 E61 V65 L77Y57-L63 VanDerWaalsContact CB-CD2 3.47Å; Y57-L63 HydrophobicContact CD1-CD2 4.19Å; Y57-L63 HydrophobicContact CD2-CD2 4.01Å; Y57-L63 HydrophobicContact CG-CD2 3.61Å; E60-L63 HydrophobicContact CB-CB 4Å; E60-L63 HydrophobicContact CB-CD2 3.97Å; E61-L63 PolarHBondContact O-N 3.47Å; L63-V65 HydrophobicContact CD2-CG2 4.45Å; L63-V65 HydrophobicContact CG-CG2 4.45Å; L63-L77 HydrophobicContact CD1-CB 4.17Å; L63-L77 HydrophobicContact CD2-CD2 4.49Å
64C96.2Very high90.3Very high0 Ų079.4 Ų79.40%038%0.383CS..EExtended strand (participates in β ladder)trans-122.6154.9166.1-65.50000108.8N48 Y78N48-C64 WeakPolarHBondContact OD1-CA 3.28Å; C64-Y78 HydrophobicContact CB-CD1 4.16Å; C64-Y78 HydrophobicContact CB-CD2 4.05Å; C64-Y78 HydrophobicContact CB-CE1 3.58Å; C64-Y78 HydrophobicContact CB-CE2 3.48Å; C64-Y78 VanDerWaalsContact CB-CE2 3.48Å; C64-Y78 HydrophobicContact CB-CG 4.37Å; C64-Y78 WeakPolarHBondContact CB-OH 3.37Å; C64-Y78 PolarHBondContact N-O 3.08Å; C64-Y78 WeakPolarHBondContact O-CD1 3.48Å; C64-Y78 PolarHBondContact O-N 3.06Å
65V96.9Very high90.4Very high0 Ų074.2 Ų74.20%036%0.357CS..EExtended strand (participates in β ladder)trans-132115.1-178.9-178.30000109N48 D49 Y52 I53 L63 R75 L77N48-V65 CarbonylContact C-O 3.49Å; N48-V65 WeakPolarHBondContact CA-O 3.47Å; N48-V65 PolarHBondContact OD1-N 2.69Å; D49-V65 PolarHBondContact N-O 3.29Å; Y52-V65 HydrophobicContact CD1-CB 4.46Å; Y52-V65 HydrophobicContact CD1-CG1 3.81Å; Y52-V65 HydrophobicContact CD1-CG2 4.3Å; Y52-V65 HydrophobicContact CE1-CG1 4.34Å; Y52-V65 HydrophobicContact CG-CG1 4.38Å; I53-V65 HydrophobicContact CD1-CB 4.31Å; I53-V65 HydrophobicContact CD1-CG2 3.94Å; I53-V65 HydrophobicContact CG1-CB 4.08Å; I53-V65 HydrophobicContact CG1-CG2 3.46Å; I53-V65 VanDerWaalsContact CG1-CG2 3.46Å; L63-V65 HydrophobicContact CD2-CG2 4.45Å; L63-V65 HydrophobicContact CG-CG2 4.45Å; V65-R75 HydrophobicContact CG1-CG 3.76Å; V65-L77 HydrophobicContact CG2-CG 4.06Å
66L96.9Very high90.6Very high3 Ų366.6 Ų66.62%0.01633%0.325CS..  trans-61.5135.6175.6-173.670000109S46 V69 R75 V76 Y78 V162 L165 I166S46-L66 WeakPolarHBondContact O-CD1 3.35Å; L66-V69 HydrophobicContact CD2-CG2 3.46Å; L66-V69 VanDerWaalsContact CD2-CG2 3.46Å; L66-V69 HydrophobicContact CG-CG2 4.11Å; L66-R75 PolarHBondContact O-NE 2.96Å; L66-R75 PolarHBondContact O-NH2 2.93Å; L66-V76 HydrophobicContact CB-CB 4.22Å; L66-V76 HydrophobicContact CD2-CB 4.49Å; L66-V76 PolarHBondContact N-O 3.42Å; L66-Y78 HydrophobicContact CB-CE1 4.44Å; L66-V162 HydrophobicContact CD1-CG1 4.37Å; L66-V162 HydrophobicContact CD1-CG2 4.01Å; L66-V162 HydrophobicContact CD2-CG1 4.43Å; L66-L165 HydrophobicContact CD2-CB 4.49Å; L66-I166 HydrophobicContact CD2-CG1 4.22Å
67P95.3Very high91Very high33 Ų3363.9 Ų63.921%0.21431%0.312CS..  trans-45.9160.8169.2-30.938.4000114Q45 S46 V69 R75Q45-P67 WeakPolarHBondContact O-CG 3.39Å; S46-P67 VanDerWaalsContact O-CD 3.28Å; S46-P67 WeakPolarHBondContact O-CD 3.44Å; P67-V69 PolarHBondContact O-N 3.2Å; P67-V69 VanDerWaalsContact O-N 3.16Å; P67-R75 VanDerWaalsContact C-CZ 3.47Å
68P94.2Very high91.3Very high99 Ų9962.7 Ų62.764%0.64331%0.307SS*.PPolyproline II helixtrans-61.8124.6177.92.510000109.1R75P68-R75 VanDerWaalsContact N-NH1 3.14Å
69V92.4Very high91.9Very high44 Ų4457.8 Ų57.827%0.26729%0.289SS..PPolyproline II helixtrans-94.3125.2179.8-1770000108.9L66 P67 G71 E72 I166L66-V69 HydrophobicContact CD2-CG2 3.46Å; L66-V69 VanDerWaalsContact CD2-CG2 3.46Å; L66-V69 HydrophobicContact CG-CG2 4.11Å; P67-V69 PolarHBondContact O-N 3.2Å; P67-V69 VanDerWaalsContact O-N 3.16Å; V69-G71 PolarHBondContact O-N 2.91Å; V69-E72 HydrophobicContact CB-CB 4.11Å; V69-E72 HydrophobicContact CB-CG 3.87Å; V69-E72 HydrophobicContact CG1-CB 4.46Å; V69-E72 HydrophobicContact CG1-CG 3.72Å; V69-E72 PolarHBondContact O-N 3.21Å; V69-E72 VanDerWaalsContact O-N 3.12Å; V69-I166 HydrophobicContact CG1-CD1 3.74Å; V69-I166 HydrophobicContact CG1-CG1 4.23Å; V69-I166 HydrophobicContact CG2-CD1 4.22Å; V69-I166 HydrophobicContact CG2-CG1 4.15Å
70R90.4Very high92.4Very high226 Ų22649.1 Ų49.185%0.85325%0.251SS*.THydrogen-bonded Turntrans-60.2127.1178.3-177.4-178.1179.8-175.30.2110.1E72R70-E72 VanDerWaalsContact C-N 3.34Å
71G87.1Confident93Very high65 Ų6548.7 Ų48.767%0.6725%0.25SS*.THydrogen-bonded Turntrans91.8-9.8179.700000114.2V69V69-G71 PolarHBondContact O-N 2.91Å
72E91.6Very high93.7Very high28 Ų2843.4 Ų43.413%0.13123%0.226CC..  trans-101.9134.2176.4-55.7-53.2150.400111V69 R70 I166 N170 Y171V69-E72 HydrophobicContact CB-CB 4.11Å; V69-E72 HydrophobicContact CB-CG 3.87Å; V69-E72 HydrophobicContact CG1-CB 4.46Å; V69-E72 HydrophobicContact CG1-CG 3.72Å; V69-E72 PolarHBondContact O-N 3.21Å; V69-E72 VanDerWaalsContact O-N 3.12Å; R70-E72 VanDerWaalsContact C-N 3.34Å; E72-I166 HydrophobicContact CG-CG2 4.04Å; E72-N170 VanDerWaalsContact OE2-CB 3.3Å; E72-N170 WeakPolarHBondContact OE2-CB 3.5Å; E72-Y171 PolarHBondContact OE1-OH 3.26Å; E72-Y171 VanDerWaalsContact OE1-OH 3.04Å; E72-Y171 PolarHBondContact OE2-OH 3.03Å
73N84.7Confident94.2Very high77 Ų7740.8 Ų40.841%0.41221%0.211SC..SBendtrans-83.6-23.3-175.8-66.8-8.5000112.6L8 R454 N485L8-N73 WeakPolarHBondContact CB-O 3.34Å; N73-R454 WeakPolarHBondContact ND2-CD 3.25Å; N73-N485 PolarHBondContact ND2-OD1 2.97Å
74R92.3Very high94.3Very high20 Ų2046.3 Ų46.38%0.07524%0.237CC..SBendtrans-110.7136.7-174.7-59.5168.2171.3-71.9-21.7111.5L8 E9 N170 D484 N487L8-R74 HydrophobicContact CB-CG 4.36Å; L8-R74 CarbonylContact O-C 3.58Å; L8-R74 VanDerWaalsContact O-CA 3.27Å; L8-R74 WeakPolarHBondContact O-CA 3.38Å; E9-R74 PolarHBondContact O-NH1 3.18Å; R74-N170 VanDerWaalsContact CB-OD1 3.31Å; R74-N170 WeakPolarHBondContact CB-OD1 3.48Å; R74-N170 PolarHBondContact N-OD1 2.93Å; R74-D484 PolarHBondContact NH2-O 2.95Å; R74-N487 PolarHBondContact NH1-OD1 3.13Å; R74-N487 PolarHBondContact NH2-OD1 2.87Å
75R94.5Very high94.2Very high28 Ų2849.9 Ų49.911%0.10626%0.26CS..EExtended strand (participates in β ladder)trans-72.3125.9167.6-165.271.2-174.2-135.6-1.8109.7L8 E9 S10 D49 Y52 V65 L66 P67 P68 L77L8-R75 PolarHBondContact O-N 3.13Å; E9-R75 CarbonylContact C-O 3.5Å; E9-R75 WeakPolarHBondContact CA-O 3.39Å; E9-R75 HydrophobicContact CG-CB 4.29Å; S10-R75 PolarHBondContact N-O 3.45Å; D49-R75 VanDerWaalsContact CG-NH2 3.25Å; D49-R75 IonicContact OD2-CZ 3.99Å; D49-R75 IonicContact OD2-NH1 3.53Å; D49-R75 PolarHBondContact OD2-NH1 3.33Å; D49-R75 IonicContact OD2-NH2 2.91Å; D49-R75 PolarHBondContact OD2-NH2 3.31Å; Y52-R75 HydrophobicContact CE1-CG 4.34Å; V65-R75 HydrophobicContact CG1-CG 3.76Å; L66-R75 PolarHBondContact O-NE 2.96Å; L66-R75 PolarHBondContact O-NH2 2.93Å; P67-R75 VanDerWaalsContact C-CZ 3.47Å; P68-R75 VanDerWaalsContact N-NH1 3.14Å; R75-L77 HydrophobicContact CB-CD1 4.31Å; R75-L77 HydrophobicContact CG-CD1 4.25Å; R75-L77 WeakPolarHBondContact O-CD1 3.43Å; R75-L77 PolarHBondContact O-N 2.95Å
76V97.1Very high94.1Very high3 Ų350.9 Ų50.92%0.01827%0.265CS..EExtended strand (participates in β ladder)trans-88.8109.3179.3-1750000109.7V12 L66 L165 N170V12-V76 HydrophobicContact CB-CG1 4.22Å; V12-V76 HydrophobicContact CG2-CG1 3.76Å; L66-V76 HydrophobicContact CB-CB 4.22Å; L66-V76 HydrophobicContact CD2-CB 4.49Å; L66-V76 PolarHBondContact N-O 3.42Å; V76-L165 HydrophobicContact CG1-CB 4.22Å; V76-L165 HydrophobicContact CG1-CD2 4.37Å; V76-N170 WeakPolarHBondContact CG2-ND2 3.08Å
77L96.8Very high94Very high4 Ų452.5 Ų52.52%0.02127%0.273CS..EExtended strand (participates in β ladder)trans-92.2132.4168.2-73.171.2000107E9 S10 K11 V12 Y57 L63 V65 R75E9-L77 HydrophobicContact CB-CD1 3.75Å; E9-L77 HydrophobicContact CG-CD1 3.64Å; E9-L77 WeakPolarHBondContact OE2-CD2 3.44Å; S10-L77 PolarHBondContact O-N 3.43Å; K11-L77 CarbonylContact C-O 3.57Å; K11-L77 WeakPolarHBondContact CA-O 3.41Å; V12-L77 PolarHBondContact N-O 2.59Å; Y57-L77 HydrophobicContact CD2-CD2 4.12Å; Y57-L77 HydrophobicContact CE1-CD2 4.27Å; Y57-L77 HydrophobicContact CE2-CD2 3.53Å; Y57-L77 HydrophobicContact CE2-CG 4.5Å; L63-L77 HydrophobicContact CD1-CB 4.17Å; L63-L77 HydrophobicContact CD2-CD2 4.49Å; V65-L77 HydrophobicContact CG2-CG 4.06Å; R75-L77 HydrophobicContact CB-CD1 4.31Å; R75-L77 HydrophobicContact CG-CD1 4.25Å; R75-L77 WeakPolarHBondContact O-CD1 3.43Å; R75-L77 PolarHBondContact O-N 2.95Å
78Y97.7Very high93.9Very high2 Ų253.5 Ų53.51%0.00828%0.277CS..EExtended strand (participates in β ladder)trans-139.9140.4179.867.2-83000113.1V12 V14 I41 L47 C64 L66 L165V12-Y78 WeakPolarHBondContact O-CA 3.48Å; V12-Y78 WeakPolarHBondContact O-CB 3.32Å; V14-Y78 HydrophobicContact CG2-CD2 3.64Å; V14-Y78 HydrophobicContact CG2-CG 4.19Å; I41-Y78 HydrophobicContact CG2-CE2 4.23Å; I41-Y78 WeakPolarHBondContact CG2-OH 3.27Å; L47-Y78 WeakPolarHBondContact O-CE1 3.42Å; L47-Y78 PolarHBondContact O-OH 2.79Å; C64-Y78 HydrophobicContact CB-CD1 4.16Å; C64-Y78 HydrophobicContact CB-CD2 4.05Å; C64-Y78 HydrophobicContact CB-CE1 3.58Å; C64-Y78 HydrophobicContact CB-CE2 3.48Å; C64-Y78 VanDerWaalsContact CB-CE2 3.48Å; C64-Y78 HydrophobicContact CB-CG 4.37Å; C64-Y78 WeakPolarHBondContact CB-OH 3.37Å; C64-Y78 PolarHBondContact N-O 3.08Å; C64-Y78 WeakPolarHBondContact O-CD1 3.48Å; C64-Y78 PolarHBondContact O-N 3.06Å; L66-Y78 HydrophobicContact CB-CE1 4.44Å; Y78-L165 HydrophobicContact CD1-CD1 3.94Å; Y78-L165 HydrophobicContact CD1-CD2 4.03Å; Y78-L165 HydrophobicContact CD2-CD1 4.48Å; Y78-L165 HydrophobicContact CD2-CD2 4.14Å; Y78-L165 HydrophobicContact CE1-CD1 3.78Å; Y78-L165 HydrophobicContact CE2-CD1 4.33Å; Y78-L165 HydrophobicContact CG-CD1 4.28Å; Y78-L165 HydrophobicContact CG-CD2 3.73Å
79R96.7Very high93.9Very high91 Ų9148.9 Ų48.934%0.34325%0.247SC..EExtended strand (participates in β ladder)trans-107.1129.2174.7-176.5173.5-68.3175.52.7108.8V12 V14 E60 N62 Y111V12-R79 PolarHBondContact O-N 3.14Å; V12-R79 VanDerWaalsContact O-N 3.1Å; V14-R79 PolarHBondContact N-O 3.32Å; E60-R79 IonicContact OE2-NH2 3.35Å; N62-R79 HydrophobicContact CB-CG 4.41Å; N62-R79 WeakPolarHBondContact O-CA 3.43Å; R79-Y111 HydrophobicContact CB-CE1 4.42Å
80L95.6Very high94Very high5 Ų550.5 Ų50.53%0.02626%0.26CS..EExtended strand (participates in β ladder)trans-98.9122.6176.8-170.6153.1000110V14 L38 I41 E82 L117V14-L80 HydrophobicContact CB-CB 4.35Å; V14-L80 HydrophobicContact CB-CG 4.39Å; V14-L80 HydrophobicContact CG1-CD1 4.28Å; V14-L80 HydrophobicContact CG1-CG 4.27Å; V14-L80 CarbonylContact O-C 3.51Å; V14-L80 WeakPolarHBondContact O-CA 3.31Å; L38-L80 HydrophobicContact CB-CD2 4.46Å; L38-L80 HydrophobicContact CD1-CB 4.2Å; L38-L80 HydrophobicContact CD1-CD2 4.44Å; I41-L80 HydrophobicContact CD1-CD1 3.65Å; L80-E82 HydrophobicContact CD2-CB 4.24Å; L80-L117 HydrophobicContact CD1-CD1 4.4Å
81I95.7Very high94.2Very high63 Ų6345.2 Ų45.232%0.32325%0.248SC..EExtended strand (participates in β ladder)trans-106.4115.5171-61-176.4000107.9L13 V14 L15 Y16L13-I81 HydrophobicContact CD1-CD1 3.68Å; L13-I81 HydrophobicContact CD1-CG1 3.89Å; V14-I81 PolarHBondContact O-N 3.34Å; L15-I81 HydrophobicContact CD2-CB 4.06Å; L15-I81 HydrophobicContact CD2-CD1 4.38Å; Y16-I81 PolarHBondContact N-O 3.38Å
82E96.4Very high94.6Very high43 Ų4343.3 Ų43.320%0.20122%0.222CC..EExtended strand (participates in β ladder)trans-86.6132.6176.3-170.9169.911400110.8Y16 A34 N35 L80 L86Y16-E82 HydrophobicContact CD1-CB 4.38Å; Y16-E82 HydrophobicContact CD1-CG 3.72Å; Y16-E82 HydrophobicContact CE1-CG 4.25Å; A34-E82 WeakPolarHBondContact CA-OE1 3.41Å; N35-E82 VanDerWaalsContact N-CD 3.34Å; N35-E82 PolarHBondContact N-OE1 3.44Å; N35-E82 PolarHBondContact N-OE2 3.1Å; L80-E82 HydrophobicContact CD2-CB 4.24Å; E82-L86 HydrophobicContact CG-CD1 4.33Å; E82-L86 HydrophobicContact CG-CD2 3.83Å; E82-L86 HydrophobicContact CG-CG 4.21Å
83Y96.6Very high94.7Very high9 Ų944.2 Ų44.24%0.03523%0.231CC..EExtended strand (participates in β ladder)trans-83.6139.3177.3-80.827.9000110.5L15 Y16 T17 P85 L86 R99 I100 N103L15-Y83 HydrophobicContact CB-CE1 4.23Å; L15-Y83 HydrophobicContact CD2-CE1 4.29Å; Y16-Y83 WeakPolarHBondContact O-CB 3.43Å; Y16-Y83 PolarHBondContact O-N 3.21Å; T17-Y83 HydrophobicContact CG2-CD2 4.08Å; T17-Y83 HydrophobicContact CG2-CE2 4.02Å; T17-Y83 HydrophobicContact CG2-CG 4.49Å; Y83-P85 CarbonylContact O-C 3.6Å; Y83-P85 VanDerWaalsContact O-C 3.28Å; Y83-L86 WeakPolarHBondContact O-CD2 3.1Å; Y83-L86 WeakPolarHBondContact O-CG 3.45Å; Y83-L86 PolarHBondContact O-N 2.91Å; Y83-R99 HydrophobicContact CE2-CG 3.9Å; Y83-I100 HydrophobicContact CE2-CG1 3.89Å; Y83-I100 VanDerWaalsContact OH-CA 3.31Å; Y83-I100 WeakPolarHBondContact OH-CA 3.34Å; Y83-N103 PolarHBondContact OH-OD1 3.07Å; Y83-N103 VanDerWaalsContact OH-OD1 3.05Å
84E94.6Very high95.3Very high130 Ų13042.4 Ų42.461%0.60722%0.22SC*.EExtended strand (participates in β ladder)trans-111.9126.4168.3-175.858.3-138.100109.2R99E84-R99 PolarHBondContact O-NH1 2.99Å; E84-R99 PolarHBondContact O-NH2 2.8Å
85P94.7Very high95.5Very high75 Ų7546.1 Ų46.149%0.48724%0.239SC..EExtended strand (participates in β ladder)cis-70.2157-15.233-35.6000111.8Y83 L87Y83-P85 CarbonylContact O-C 3.6Å; Y83-P85 VanDerWaalsContact O-C 3.28Å; P85-L87 HydrophobicContact CG-CD2 4.11Å
86L95.6Very high95.6Very high21 Ų2147 Ų4711%0.1125%0.245CC..EExtended strand (participates in β ladder)trans-71.3139.3164.1-70.7172.3000109.9Y16 P32 E82 Y83Y16-L86 HydrophobicContact CD1-CD1 4.44Å; Y16-L86 HydrophobicContact CD1-CD2 3.69Å; Y16-L86 HydrophobicContact CD2-CD2 4.34Å; Y16-L86 HydrophobicContact CE1-CD1 3.56Å; Y16-L86 HydrophobicContact CE1-CD2 3.49Å; Y16-L86 VanDerWaalsContact CE1-CD2 3.49Å; Y16-L86 HydrophobicContact CE1-CG 4.19Å; Y16-L86 HydrophobicContact CE2-CD2 4.2Å; Y16-L86 HydrophobicContact CG-CD2 4.09Å; P32-L86 HydrophobicContact CB-CB 3.58Å; P32-L86 HydrophobicContact CB-CD1 4.25Å; E82-L86 HydrophobicContact CG-CD1 4.33Å; E82-L86 HydrophobicContact CG-CD2 3.83Å; E82-L86 HydrophobicContact CG-CG 4.21Å; Y83-L86 WeakPolarHBondContact O-CD2 3.1Å; Y83-L86 WeakPolarHBondContact O-CG 3.45Å; Y83-L86 PolarHBondContact O-N 2.91Å
87L93.6Very high95.6Very high36 Ų3647.9 Ų47.919%0.18825%0.248CC..EExtended strand (participates in β ladder)trans-114.3141.3-174.3-61.8176.9000112.2T17 G18 G19 P85 M92 E96T17-L87 PolarHBondContact O-N 3.47Å; G18-L87 CarbonylContact C-O 3.51Å; G18-L87 VanDerWaalsContact CA-O 3.31Å; G18-L87 WeakPolarHBondContact CA-O 2.97Å; G19-L87 PolarHBondContact N-O 3.05Å; P85-L87 HydrophobicContact CG-CD2 4.11Å; L87-M92 HydrophobicContact CD1-CG 4.41Å; L87-E96 HydrophobicContact CD1-CG 3.38Å
88D92.8Very high95.7Very high55 Ų5549.4 Ų49.429%0.29426%0.257SS..  trans-64.1135.6149.2-169.5-49.4000108.1C90 N91D88-C90 PolarHBondContact O-N 2.97Å; D88-C90 VanDerWaalsContact O-N 3.1Å; D88-C90 WeakPolarHBondContact OD1-CB 3.48Å; D88-C90 PolarHBondContact OD1-N 3.47Å; D88-N91 WeakPolarHBondContact O-CB 2.88Å; D88-N91 PolarHBondContact O-N 2.95Å
89S95.9Very high95.7Very high1 Ų154.1 Ų54.11%0.00728%0.275CS..G310 helixtrans-59.6-23.4-178.461.50000113.8N91 M92 G119 D121 T122S89-N91 PolarHBondContact O-N 3.15Å; S89-M92 WeakPolarHBondContact O-CB 3.41Å; S89-M92 PolarHBondContact O-N 3.24Å; S89-M92 VanDerWaalsContact O-N 3.15Å; S89-G119 WeakPolarHBondContact CB-O 3.37Å; S89-G119 VanDerWaalsContact OG-C 3.24Å; S89-G119 WeakPolarHBondContact OG-CA 3.29Å; S89-G119 PolarHBondContact OG-O 3.1Å; S89-D121 WeakPolarHBondContact OG-CB 3.45Å; S89-D121 PolarHBondContact OG-N 2.91Å; S89-T122 VanDerWaalsContact CB-OG1 3.29Å; S89-T122 WeakPolarHBondContact CB-OG1 3.41Å; S89-T122 VanDerWaalsContact O-CG2 3.28Å; S89-T122 WeakPolarHBondContact O-CG2 3.37Å; S89-T122 PolarHBondContact O-OG1 2.92Å; S89-T122 PolarHBondContact OG-N 3.5Å
90C93.6Very high95.8Very high79 Ų7949.9 Ų49.953%0.53426%0.259SS..G310 helixtrans-62-22.4172.3-67.10000113.6D88D88-C90 PolarHBondContact O-N 2.97Å; D88-C90 VanDerWaalsContact O-N 3.1Å; D88-C90 WeakPolarHBondContact OD1-CB 3.48Å; D88-C90 PolarHBondContact OD1-N 3.47Å
91N94.7Very high95.9Very high115 Ų11549.6 Ų49.662%0.61526%0.258SS*.G310 helixtrans-96.24.8178.6-65-48.1000113.3D88 S89D88-N91 WeakPolarHBondContact O-CB 2.88Å; D88-N91 PolarHBondContact O-N 2.95Å; S89-N91 PolarHBondContact O-N 3.15Å
92M95Very high96Very high24 Ų2451.5 Ų51.512%0.11826%0.264CS..  trans-74.7141.7176.4-69.9-143.3-167.600112.3T17 L87 S89 E96 H118T17-M92 HydrophobicContact CG2-CE 4.41Å; T17-M92 VanDerWaalsContact OG1-CE 3.22Å; T17-M92 WeakPolarHBondContact OG1-CE 3.1Å; L87-M92 HydrophobicContact CD1-CG 4.41Å; S89-M92 WeakPolarHBondContact O-CB 3.41Å; S89-M92 PolarHBondContact O-N 3.24Å; S89-M92 VanDerWaalsContact O-N 3.15Å; M92-E96 HydrophobicContact CG-CB 4.47Å; M92-E96 HydrophobicContact SD-CB 4.2Å; M92-H118 WeakPolarHBondContact CE-CD2 3.41Å; M92-H118 WeakPolarHBondContact CE-NE2 2.9Å; M92-H118 PolarHBondContact SD-NE2 3.3Å
93S94.5Very high96.1Very high47 Ų4751.7 Ų51.733%0.32927%0.266SS..  trans-132.3-177.1177.281.60000111.6M95 E96 W97S93-M95 PolarHBondContact O-N 3.03Å; S93-M95 VanDerWaalsContact O-N 3.14Å; S93-M95 PolarHBondContact OG-N 2.89Å; S93-M95 VanDerWaalsContact OG-N 3.15Å; S93-E96 WeakPolarHBondContact CA-OE2 3.33Å; S93-E96 VanDerWaalsContact CB-OE2 3.32Å; S93-E96 WeakPolarHBondContact CB-OE2 3.3Å; S93-E96 PolarHBondContact N-OE2 3.39Å; S93-E96 PolarHBondContact O-N 3.04Å; S93-E96 PolarHBondContact OG-OE2 3.27Å; S93-W97 PolarHBondContact O-N 2.87Å
94F96.1Very high96.2Very high40 Ų4051.3 Ų51.318%0.17526%0.264CS..Hα-helixtrans-52.7-31.2171-64.7-87.1000113.1W97 T98 L238 R240 I242 A358F94-W97 AromaticContact CD1-CE3 3.87Å; F94-W97 HydrophobicContact CD1-CE3 3.87Å; F94-W97 AromaticContact CD1-CZ3 3.76Å; F94-W97 HydrophobicContact CD1-CZ3 3.76Å; F94-W97 HydrophobicContact CE1-CE3 4.36Å; F94-W97 AromaticContact CE1-CZ3 3.81Å; F94-W97 HydrophobicContact CE1-CZ3 3.81Å; F94-W97 HydrophobicContact CG-CE3 4.33Å; F94-W97 HydrophobicContact CG-CZ3 4.3Å; F94-W97 HydrophobicContact CZ-CZ3 4.37Å; F94-T98 PolarHBondContact O-N 2.94Å; F94-T98 PolarHBondContact O-OG1 2.82Å; F94-T98 VanDerWaalsContact O-OG1 3.06Å; F94-L238 HydrophobicContact CD1-CB 3.66Å; F94-L238 HydrophobicContact CD1-CD1 3.95Å; F94-L238 HydrophobicContact CD1-CG 4.47Å; F94-L238 HydrophobicContact CE1-CB 3.95Å; F94-L238 HydrophobicContact CE1-CD1 4.34Å; F94-R240 HydrophobicContact CB-CG 4.43Å; F94-R240 HydrophobicContact CD1-CG 4.41Å; F94-R240 HydrophobicContact CD2-CB 4.22Å; F94-R240 HydrophobicContact CD2-CG 3.72Å; F94-R240 HydrophobicContact CE2-CB 4.03Å; F94-R240 HydrophobicContact CE2-CG 4.01Å; F94-R240 HydrophobicContact CG-CG 3.94Å; F94-R240 HydrophobicContact CZ-CB 4.46Å; F94-R240 HydrophobicContact CZ-CG 4.46Å; F94-I242 HydrophobicContact CZ-CD1 4.33Å; F94-I242 HydrophobicContact CZ-CG1 4.44Å; F94-A358 HydrophobicContact CE1-CB 3.88Å; F94-A358 HydrophobicContact CZ-CB 4.47Å
95M96.4Very high96.3Very high98 Ų9848.5 Ų48.548%0.48325%0.251SS..Hα-helixtrans-66.1-44.3179.8-67.5-56.8-56.100112S93 T98 R99 R240S93-M95 PolarHBondContact O-N 3.03Å; S93-M95 VanDerWaalsContact O-N 3.14Å; S93-M95 PolarHBondContact OG-N 2.89Å; S93-M95 VanDerWaalsContact OG-N 3.15Å; M95-T98 WeakPolarHBondContact O-CB 3.46Å; M95-T98 PolarHBondContact O-N 3.34Å; M95-R99 PolarHBondContact O-N 3.37Å; M95-R240 PolarHBondContact SD-NH2 2.63Å
96E97.1Very high96.4Very high46 Ų4649.4 Ų49.422%0.21525%0.252CS..Hα-helixtrans-66.8-40.1179.3-71.758.3-120.500110.6L87 M92 S93 T98 R99 I100L87-E96 HydrophobicContact CD1-CG 3.38Å; M92-E96 HydrophobicContact CG-CB 4.47Å; M92-E96 HydrophobicContact SD-CB 4.2Å; S93-E96 WeakPolarHBondContact CA-OE2 3.33Å; S93-E96 VanDerWaalsContact CB-OE2 3.32Å; S93-E96 WeakPolarHBondContact CB-OE2 3.3Å; S93-E96 PolarHBondContact N-OE2 3.39Å; S93-E96 PolarHBondContact O-N 3.04Å; S93-E96 PolarHBondContact OG-OE2 3.27Å; E96-T98 PolarHBondContact O-N 3.05Å; E96-R99 WeakPolarHBondContact O-CB 3.41Å; E96-R99 PolarHBondContact O-N 2.69Å; E96-I100 VanDerWaalsContact O-CG1 3.27Å; E96-I100 WeakPolarHBondContact O-CG1 3.38Å; E96-I100 PolarHBondContact O-N 3.43Å
97W97.9Very high96.4Very high22 Ų2250.2 Ų50.28%0.08326%0.259CS..Hα-helixtrans-60.3-44.6173.2-60.4-19.5000111.9S93 F94 R99 I100 A101 T126 A129 M133 L238 T355S93-W97 PolarHBondContact O-N 2.87Å; F94-W97 AromaticContact CD1-CE3 3.87Å; F94-W97 HydrophobicContact CD1-CE3 3.87Å; F94-W97 AromaticContact CD1-CZ3 3.76Å; F94-W97 HydrophobicContact CD1-CZ3 3.76Å; F94-W97 HydrophobicContact CE1-CE3 4.36Å; F94-W97 AromaticContact CE1-CZ3 3.81Å; F94-W97 HydrophobicContact CE1-CZ3 3.81Å; F94-W97 HydrophobicContact CG-CE3 4.33Å; F94-W97 HydrophobicContact CG-CZ3 4.3Å; F94-W97 HydrophobicContact CZ-CZ3 4.37Å; W97-R99 VanDerWaalsContact C-N 3.34Å; W97-R99 PolarHBondContact O-N 2.81Å; W97-I100 PolarHBondContact O-N 3.33Å; W97-A101 WeakPolarHBondContact O-CB 3.49Å; W97-A101 PolarHBondContact O-N 3.32Å; W97-T126 PolarHBondContact NE1-OG1 3.38Å; W97-A129 HydrophobicContact CD2-CB 3.56Å; W97-A129 HydrophobicContact CE3-CB 3.45Å; W97-A129 VanDerWaalsContact CE3-CB 3.45Å; W97-A129 HydrophobicContact CG-CB 4.11Å; W97-A129 HydrophobicContact CH2-CB 4.21Å; W97-A129 HydrophobicContact CZ2-CB 4.3Å; W97-A129 HydrophobicContact CZ3-CB 3.8Å; W97-M133 HydrophobicContact CB-SD 4.01Å; W97-L238 HydrophobicContact CE3-CD1 3.96Å; W97-L238 HydrophobicContact CZ3-CD1 4.47Å; W97-T355 HydrophobicContact CH2-CG2 4.22Å; W97-T355 HydrophobicContact CZ3-CG2 4.37Å
98T97.9Very high96.6Very high35 Ų3549.1 Ų49.122%0.21525%0.252CS..Hα-helixtrans-58.5-44172.7-62.30000111.8F94 M95 E96 A101 K102 Y236F94-T98 PolarHBondContact O-N 2.94Å; F94-T98 PolarHBondContact O-OG1 2.82Å; F94-T98 VanDerWaalsContact O-OG1 3.06Å; M95-T98 WeakPolarHBondContact O-CB 3.46Å; M95-T98 PolarHBondContact O-N 3.34Å; E96-T98 PolarHBondContact O-N 3.05Å; T98-A101 PolarHBondContact O-N 3.31Å; T98-K102 VanDerWaalsContact O-CB 3.28Å; T98-K102 WeakPolarHBondContact O-CB 3.47Å; T98-K102 PolarHBondContact O-N 3.38Å; T98-Y236 HydrophobicContact CG2-CD1 3.85Å; T98-Y236 HydrophobicContact CG2-CG 4.29Å; T98-Y236 PolarHBondContact OG1-O 2.8Å
99R97.9Very high96.6Very high102 Ų10251 Ų5139%0.38526%0.26SS..Hα-helixtrans-62-48.5177.9-175.5-179.9177.8176.52.5111.7Y83 E84 M95 E96 W97 K102 N103Y83-R99 HydrophobicContact CE2-CG 3.9Å; E84-R99 PolarHBondContact O-NH1 2.99Å; E84-R99 PolarHBondContact O-NH2 2.8Å; M95-R99 PolarHBondContact O-N 3.37Å; E96-R99 WeakPolarHBondContact O-CB 3.41Å; E96-R99 PolarHBondContact O-N 2.69Å; W97-R99 VanDerWaalsContact C-N 3.34Å; W97-R99 PolarHBondContact O-N 2.81Å; R99-K102 PolarHBondContact O-N 3.02Å; R99-N103 PolarHBondContact O-N 2.89Å
100I98.5Very high96.4Very high1 Ų154.9 Ų54.91%0.00529%0.286CS..Hα-helixtrans-57.4-51.7175.6-64.7162.9000110.8L15 T17 Y83 E96 W97 K102 N103 I104 I116 T126 L130L15-I100 HydrophobicContact CD1-CG2 4.18Å; T17-I100 HydrophobicContact CG2-CD1 3.85Å; T17-I100 HydrophobicContact CG2-CG1 3.99Å; Y83-I100 HydrophobicContact CE2-CG1 3.89Å; Y83-I100 VanDerWaalsContact OH-CA 3.31Å; Y83-I100 WeakPolarHBondContact OH-CA 3.34Å; E96-I100 VanDerWaalsContact O-CG1 3.27Å; E96-I100 WeakPolarHBondContact O-CG1 3.38Å; E96-I100 PolarHBondContact O-N 3.43Å; W97-I100 PolarHBondContact O-N 3.33Å; I100-K102 VanDerWaalsContact C-N 3.31Å; I100-K102 PolarHBondContact O-N 2.97Å; I100-N103 PolarHBondContact O-N 2.83Å; I100-I104 HydrophobicContact CG2-CD1 4.09Å; I100-I104 PolarHBondContact O-N 3Å; I100-I104 VanDerWaalsContact O-N 3.08Å; I100-I116 HydrophobicContact CG2-CD1 3.63Å; I100-I116 HydrophobicContact CG2-CG1 4.19Å; I100-T126 HydrophobicContact CD1-CG2 4.19Å; I100-L130 HydrophobicContact CB-CD2 4.35Å; I100-L130 HydrophobicContact CG2-CD1 3.86Å; I100-L130 HydrophobicContact CG2-CD2 4.04Å
101A98.5Very high96.5Very high0 Ų052.4 Ų52.40%027%0.266CS..Hα-helixtrans-60.9-40.9-178.700000112W97 T98 H105 L130 M133 F134 V234 Y236W97-A101 WeakPolarHBondContact O-CB 3.49Å; W97-A101 PolarHBondContact O-N 3.32Å; T98-A101 PolarHBondContact O-N 3.31Å; A101-H105 VanDerWaalsContact O-CB 3.29Å; A101-H105 WeakPolarHBondContact O-CB 3.33Å; A101-H105 PolarHBondContact O-N 3.04Å; A101-L130 HydrophobicContact CB-CD2 4.01Å; A101-M133 HydrophobicContact CB-CE 3.46Å; A101-M133 VanDerWaalsContact CB-CE 3.46Å; A101-M133 HydrophobicContact CB-SD 4.37Å; A101-F134 HydrophobicContact CB-CE2 3.75Å; A101-F134 HydrophobicContact CB-CZ 4.03Å; A101-F134 WeakPolarHBondContact O-CZ 3.33Å; A101-V234 HydrophobicContact CB-CG1 3.78Å; A101-Y236 HydrophobicContact CB-CD1 4.49Å; A101-Y236 HydrophobicContact CB-CE1 4.26Å
102K98.3Very high96.6Very high103 Ų10348.4 Ų48.445%0.44824%0.244SC..Hα-helixtrans-64.1-45.7177.6-174.5-179.1173.566.60111.7T98 R99 I100 I104 H105 D106 Y236T98-K102 VanDerWaalsContact O-CB 3.28Å; T98-K102 WeakPolarHBondContact O-CB 3.47Å; T98-K102 PolarHBondContact O-N 3.38Å; R99-K102 PolarHBondContact O-N 3.02Å; I100-K102 VanDerWaalsContact C-N 3.31Å; I100-K102 PolarHBondContact O-N 2.97Å; K102-I104 PolarHBondContact O-N 3.14Å; K102-H105 PolarHBondContact O-N 3.13Å; K102-D106 WeakPolarHBondContact CG-OD2 3.31Å; K102-D106 IonicContact NZ-OD2 3.69Å; K102-D106 WeakPolarHBondContact O-CB 3.36Å; K102-D106 PolarHBondContact O-N 3.02Å; K102-Y236 HydrophobicContact CB-CE1 3.83Å
103N97.8Very high96.7Very high47 Ų4747.2 Ų47.225%0.25124%0.239SC..Hα-helixtrans-65-38.4-179.9-68.9162.8000112.7L15 Y83 R99 I100 C107L15-N103 HydrophobicContact CD1-CB 4.27Å; Y83-N103 PolarHBondContact OH-OD1 3.07Å; Y83-N103 VanDerWaalsContact OH-OD1 3.05Å; R99-N103 PolarHBondContact O-N 2.89Å; I100-N103 PolarHBondContact O-N 2.83Å; N103-C107 WeakPolarHBondContact O-CB 3.29Å; N103-C107 PolarHBondContact O-N 3.02Å
104I98.4Very high96.9Very high0 Ų045 Ų450%022%0.223CC..Hα-helixtrans-64.1-46.6172.4-68.9175.5000110.6L15 I100 K102 C107 Y108 F114 I116 F134 I141L15-I104 HydrophobicContact CD1-CD1 4.22Å; L15-I104 HydrophobicContact CD1-CG1 3.69Å; I100-I104 HydrophobicContact CG2-CD1 4.09Å; I100-I104 PolarHBondContact O-N 3Å; I100-I104 VanDerWaalsContact O-N 3.08Å; K102-I104 PolarHBondContact O-N 3.14Å; I104-C107 CarbonylContact O-C 3.58Å; I104-C107 PolarHBondContact O-N 3.28Å; I104-Y108 HydrophobicContact CG2-CD2 4.13Å; I104-Y108 WeakPolarHBondContact O-CA 3.37Å; I104-Y108 WeakPolarHBondContact O-CB 3.44Å; I104-Y108 PolarHBondContact O-N 2.92Å; I104-F114 HydrophobicContact CB-CD1 4.21Å; I104-F114 HydrophobicContact CB-CE1 4.44Å; I104-F114 HydrophobicContact CD1-CB 4.19Å; I104-F114 HydrophobicContact CD1-CG 4.35Å; I104-F114 HydrophobicContact CG1-CB 4.35Å; I104-F114 HydrophobicContact CG1-CD1 3.88Å; I104-F114 HydrophobicContact CG1-CG 4.11Å; I104-F114 HydrophobicContact CG2-CD1 3.87Å; I104-F114 HydrophobicContact CG2-CD2 3.88Å; I104-F114 HydrophobicContact CG2-CE1 3.95Å; I104-F114 HydrophobicContact CG2-CE2 3.96Å; I104-F114 HydrophobicContact CG2-CG 3.87Å; I104-F114 HydrophobicContact CG2-CZ 4.04Å; I104-I116 HydrophobicContact CD1-CD1 4Å; I104-I116 HydrophobicContact CD1-CG1 4.38Å; I104-F134 HydrophobicContact CB-CE1 4.36Å; I104-F134 HydrophobicContact CB-CZ 3.77Å; I104-F134 HydrophobicContact CD1-CZ 4.38Å; I104-F134 HydrophobicContact CG2-CE1 3.72Å; I104-F134 HydrophobicContact CG2-CZ 3.57Å; I104-I141 HydrophobicContact CD1-CD1 4.09Å; I104-I141 HydrophobicContact CD1-CG1 4.37Å; I104-I141 HydrophobicContact CD1-CG2 4.01Å; I104-I141 HydrophobicContact CG2-CD1 4.11Å
105H97.6Very high97.1Very high71 Ų7143.1 Ų43.133%0.32922%0.215SC..Hα-helixtrans-59.8-48.3-179.9-179.5-108000112.5A101 K102 C107 Y108 V234 Y236A101-H105 VanDerWaalsContact O-CB 3.29Å; A101-H105 WeakPolarHBondContact O-CB 3.33Å; A101-H105 PolarHBondContact O-N 3.04Å; K102-H105 PolarHBondContact O-N 3.13Å; H105-C107 PolarHBondContact O-N 3.29Å; H105-Y108 VanDerWaalsContact O-CB 3.29Å; H105-Y108 WeakPolarHBondContact O-CB 3.49Å; H105-Y108 PolarHBondContact O-N 3.45Å; H105-Y108 VanDerWaalsContact O-N 3.11Å; H105-V234 HydrophobicContact CB-CG2 3.96Å; H105-Y236 PolarHBondContact ND1-OH 3.38Å
106D97.1Very high97.2Very high94 Ų9438.4 Ų38.450%0.50319%0.192SC..Hα-helixtrans-64.6-27.3-177.9-64.9-13.6000112K102K102-D106 WeakPolarHBondContact CG-OD2 3.31Å; K102-D106 IonicContact NZ-OD2 3.69Å; K102-D106 WeakPolarHBondContact O-CB 3.36Å; K102-D106 PolarHBondContact O-N 3.02Å
107C95.4Very high97.3Very high38 Ų3836.2 Ų36.226%0.25718%0.182SC..THydrogen-bonded Turntrans-101.87.4178-65.30000113.4L13 N103 I104 H105 E109 S110 Y111L13-C107 HydrophobicContact CD2-CB 3.9Å; N103-C107 WeakPolarHBondContact O-CB 3.29Å; N103-C107 PolarHBondContact O-N 3.02Å; I104-C107 CarbonylContact O-C 3.58Å; I104-C107 PolarHBondContact O-N 3.28Å; H105-C107 PolarHBondContact O-N 3.29Å; C107-E109 VanDerWaalsContact C-N 3.32Å; C107-E109 PolarHBondContact O-N 3.48Å; C107-S110 PolarHBondContact O-N 2.66Å; C107-Y111 HydrophobicContact CB-CD2 3.87Å; C107-Y111 HydrophobicContact CB-CE2 3.85Å; C107-Y111 WeakPolarHBondContact O-CD2 3.4Å
108Y96.3Very high97.3Very high13 Ų1335.2 Ų35.25%0.05118%0.178CC..G310 helixtrans-61.4-38.3-162.7-165.4-99000113.1I104 H105 S110 F114 L137 G138 K139 V232I104-Y108 HydrophobicContact CG2-CD2 4.13Å; I104-Y108 WeakPolarHBondContact O-CA 3.37Å; I104-Y108 WeakPolarHBondContact O-CB 3.44Å; I104-Y108 PolarHBondContact O-N 2.92Å; H105-Y108 VanDerWaalsContact O-CB 3.29Å; H105-Y108 WeakPolarHBondContact O-CB 3.49Å; H105-Y108 PolarHBondContact O-N 3.45Å; H105-Y108 VanDerWaalsContact O-N 3.11Å; Y108-S110 VanDerWaalsContact C-N 3.33Å; Y108-S110 PolarHBondContact O-N 2.94Å; Y108-F114 AromaticContact CD2-CE2 3.68Å; Y108-F114 HydrophobicContact CD2-CE2 3.68Å; Y108-F114 AromaticContact CD2-CZ 3.86Å; Y108-F114 HydrophobicContact CD2-CZ 3.86Å; Y108-F114 AromaticContact CE2-CE2 3.87Å; Y108-F114 HydrophobicContact CE2-CE2 3.87Å; Y108-F114 HydrophobicContact CE2-CZ 4.49Å; Y108-F114 HydrophobicContact CG-CZ 4.46Å; Y108-L137 HydrophobicContact CE2-CD1 3.91Å; Y108-G138 WeakPolarHBondContact OH-CA 3.45Å; Y108-G138 PolarHBondContact OH-N 3.41Å; Y108-K139 HydrophobicContact CD1-CD 4.39Å; Y108-K139 HydrophobicContact CE1-CD 3.91Å; Y108-K139 HydrophobicContact CE1-CG 4.21Å; Y108-K139 HydrophobicContact CE2-CB 4.13Å; Y108-K139 HydrophobicContact CE2-CD 4.11Å; Y108-K139 HydrophobicContact CE2-CG 4.35Å; Y108-K139 PolarHBondContact O-NZ 3.42Å; Y108-K139 PolarHBondContact OH-N 2.65Å; Y108-K139 VanDerWaalsContact OH-N 3.08Å; Y108-V232 HydrophobicContact CD1-CG1 3.61Å; Y108-V232 HydrophobicContact CD2-CG1 4.27Å; Y108-V232 HydrophobicContact CE1-CB 4.09Å; Y108-V232 HydrophobicContact CE1-CG1 3.58Å; Y108-V232 HydrophobicContact CE2-CG1 4.24Å; Y108-V232 HydrophobicContact CE2-CG2 4.41Å; Y108-V232 HydrophobicContact CG-CG1 3.95Å
109E93.9Very high97.2Very high96 Ų9633.6 Ų33.645%0.44917%0.168SC..G310 helixtrans-75.2-18.1179.8-61.3-162.2-173.300113.8C107 R507 H512C107-E109 VanDerWaalsContact C-N 3.32Å; C107-E109 PolarHBondContact O-N 3.48Å; E109-R507 IonicContact OE1-NH2 3.87Å; E109-R507 PolarHBondContact OE1-NH2 3.14Å; E109-R507 IonicContact OE2-NH2 2.86Å; E109-H512 HydrophobicContact CB-CB 4.18Å; E109-H512 HydrophobicContact CG-CB 3.9Å; E109-H512 PolarHBondContact O-CD2 2.79Å
110S92.4Very high97.2Very high81 Ų8129 Ų2957%0.56615%0.151SC*.G310 helixtrans-89.7-15.3-173.7-60.70000114.9C107 Y108C107-S110 PolarHBondContact O-N 2.66Å; Y108-S110 VanDerWaalsContact C-N 3.33Å; Y108-S110 PolarHBondContact O-N 2.94Å
111Y95.5Very high97.1Very high27 Ų2732.8 Ų32.811%0.10617%0.172CC..  trans-128.7145.8-174.5-63.2-87.7000111.5K11 V12 L13 R79 C107 F114 K139K11-Y111 HydrophobicContact CB-CD1 4.01Å; K11-Y111 CarbonylContact O-C 3.28Å; K11-Y111 WeakPolarHBondContact O-CA 3.46Å; V12-Y111 VanDerWaalsContact C-CD1 3.48Å; L13-Y111 HydrophobicContact CB-CD1 3.72Å; L13-Y111 HydrophobicContact CB-CD2 3.86Å; L13-Y111 HydrophobicContact CB-CE1 3.88Å; L13-Y111 HydrophobicContact CB-CE2 4.04Å; L13-Y111 HydrophobicContact CB-CG 3.69Å; L13-Y111 HydrophobicContact CD1-CE1 4.26Å; L13-Y111 HydrophobicContact CD1-CE2 4.19Å; L13-Y111 HydrophobicContact CD2-CD2 4.27Å; L13-Y111 HydrophobicContact CD2-CE2 4.13Å; L13-Y111 HydrophobicContact CG-CE2 4.36Å; R79-Y111 HydrophobicContact CB-CE1 4.42Å; C107-Y111 HydrophobicContact CB-CD2 3.87Å; C107-Y111 HydrophobicContact CB-CE2 3.85Å; C107-Y111 WeakPolarHBondContact O-CD2 3.4Å; Y111-F114 HydrophobicContact CD2-CE1 4.44Å; Y111-K139 WeakPolarHBondContact O-CD 3.28Å; Y111-K139 PolarHBondContact O-NZ 3.17Å
112D95.9Very high97Very high31 Ų3134.1 Ų34.117%0.16618%0.18CC..SBendtrans-78.3-25.7179-64.8-46.3000112.6S10 K11 K483S10-D112 WeakPolarHBondContact CA-OD2 2.9Å; S10-D112 WeakPolarHBondContact OG-CB 3.46Å; S10-D112 PolarHBondContact OG-OD2 3.15Å; K11-D112 PolarHBondContact N-OD2 3.11Å; K11-D112 PolarHBondContact O-N 3.05Å; D112-K483 WeakPolarHBondContact OD1-CE 3.48Å; D112-K483 IonicContact OD1-NZ 3.09Å; D112-K483 PolarHBondContact OD1-NZ 3.08Å; D112-K483 IonicContact OD2-NZ 3.94Å; D112-K483 PolarHBondContact OD2-NZ 3.25Å
113G98Very high97Very high0 Ų029.2 Ų29.20%016%0.159CC..EExtended strand (participates in β ladder)trans-163.3171.9177.400000112.5V12 L13 P140V12-G113 WeakPolarHBondContact CA-O 3.39Å; L13-G113 PolarHBondContact N-O 3.04Å; L13-G113 VanDerWaalsContact N-O 3.09Å; G113-P140 WeakPolarHBondContact CA-O 3.37Å
114F98.8Very high97.1Very high0 Ų027.1 Ų27.10%015%0.148CC..EExtended strand (participates in β ladder)trans-129.1138.6-175.2-53-88.1000110L13 I104 Y108 Y111 K139 P140 I141 V142L13-F114 HydrophobicContact CB-CD1 3.85Å; L13-F114 HydrophobicContact CB-CE1 4.16Å; L13-F114 HydrophobicContact CD2-CD1 4.11Å; L13-F114 HydrophobicContact CD2-CE1 4.18Å; L13-F114 HydrophobicContact CG-CD1 4.45Å; L13-F114 CarbonylContact O-C 3.55Å; L13-F114 WeakPolarHBondContact O-CA 3.44Å; I104-F114 HydrophobicContact CB-CD1 4.21Å; I104-F114 HydrophobicContact CB-CE1 4.44Å; I104-F114 HydrophobicContact CD1-CB 4.19Å; I104-F114 HydrophobicContact CD1-CG 4.35Å; I104-F114 HydrophobicContact CG1-CB 4.35Å; I104-F114 HydrophobicContact CG1-CD1 3.88Å; I104-F114 HydrophobicContact CG1-CG 4.11Å; I104-F114 HydrophobicContact CG2-CD1 3.87Å; I104-F114 HydrophobicContact CG2-CD2 3.88Å; I104-F114 HydrophobicContact CG2-CE1 3.95Å; I104-F114 HydrophobicContact CG2-CE2 3.96Å; I104-F114 HydrophobicContact CG2-CG 3.87Å; I104-F114 HydrophobicContact CG2-CZ 4.04Å; Y108-F114 AromaticContact CD2-CE2 3.68Å; Y108-F114 HydrophobicContact CD2-CE2 3.68Å; Y108-F114 AromaticContact CD2-CZ 3.86Å; Y108-F114 HydrophobicContact CD2-CZ 3.86Å; Y108-F114 AromaticContact CE2-CE2 3.87Å; Y108-F114 HydrophobicContact CE2-CE2 3.87Å; Y108-F114 HydrophobicContact CE2-CZ 4.49Å; Y108-F114 HydrophobicContact CG-CZ 4.46Å; Y111-F114 HydrophobicContact CD2-CE1 4.44Å; F114-K139 HydrophobicContact CE2-CB 4.32Å; F114-K139 HydrophobicContact CE2-CD 4.16Å; F114-P140 PolarHBondContact N-O 2.85Å; F114-I141 HydrophobicContact CB-CG1 4.22Å; F114-I141 HydrophobicContact CD2-CG1 4Å; F114-I141 HydrophobicContact CG-CG1 4.44Å; F114-I141 CarbonylContact O-C 3.54Å; F114-I141 WeakPolarHBondContact O-CA 3.47Å; F114-V142 PolarHBondContact O-N 3.2Å
115V98.9Very high97.1Very high0 Ų030.6 Ų30.60%016%0.161CC..EExtended strand (participates in β ladder)trans-118.7135.9169.4175.60000108.4V12 L13 V14 L15 L117 V142 T144 L161 L165 A168V12-V115 HydrophobicContact CG1-CB 4.43Å; V12-V115 HydrophobicContact CG1-CG2 3.79Å; L13-V115 PolarHBondContact O-N 2.84Å; V14-V115 CarbonylContact C-O 3.56Å; V14-V115 VanDerWaalsContact CA-O 3.3Å; V14-V115 WeakPolarHBondContact CA-O 3.45Å; V14-V115 HydrophobicContact CG1-CB 4.42Å; V14-V115 HydrophobicContact CG1-CG1 4.34Å; V14-V115 HydrophobicContact CG2-CB 4.19Å; L15-V115 PolarHBondContact N-O 3.47Å; V115-L117 HydrophobicContact CG1-CD2 4.25Å; V115-V142 CarbonylContact C-O 3.5Å; V115-V142 WeakPolarHBondContact CA-O 3.46Å; V115-V142 HydrophobicContact CG2-CB 4.42Å; V115-T144 HydrophobicContact CG1-CG2 4.17Å; V115-L161 HydrophobicContact CG1-CD1 4.46Å; V115-L165 HydrophobicContact CG2-CD2 4.24Å; V115-A168 HydrophobicContact CG2-CB 3.75Å
116I98.8Very high97.1Very high0 Ų027.2 Ų27.20%015%0.146CC..EExtended strand (participates in β ladder)trans-118114.4175.1-55.5159.9000107.7L15 T17 I100 I104 H118 L130 I141 V142 L143 T144L15-I116 CarbonylContact O-C 3.58Å; L15-I116 WeakPolarHBondContact O-CA 3.44Å; T17-I116 HydrophobicContact CG2-CG2 3.92Å; I100-I116 HydrophobicContact CG2-CD1 3.63Å; I100-I116 HydrophobicContact CG2-CG1 4.19Å; I104-I116 HydrophobicContact CD1-CD1 4Å; I104-I116 HydrophobicContact CD1-CG1 4.38Å; I116-H118 HydrophobicContact CG2-CB 4.48Å; I116-L130 HydrophobicContact CD1-CD1 3.41Å; I116-L130 VanDerWaalsContact CD1-CD1 3.41Å; I116-I141 HydrophobicContact CD1-CG2 3.64Å; I116-I141 HydrophobicContact CG1-CG2 4.43Å; I116-V142 PolarHBondContact N-O 3.15Å; I116-L143 HydrophobicContact CB-CG 4.18Å; I116-L143 HydrophobicContact CD1-CD1 4.33Å; I116-L143 HydrophobicContact CD1-CG 4.07Å; I116-L143 WeakPolarHBondContact O-CA 3.25Å; I116-T144 PolarHBondContact O-N 3.15Å
117L98.5Very high97.2Very high0 Ų022.8 Ų22.80%012%0.122CC..EExtended strand (participates in β ladder)trans-84.7120.7172.2-62-179.1000108.9V14 L15 Y16 T17 I21 L37 L80 V115 T144 L161V14-L117 HydrophobicContact CG1-CD1 3.82Å; V14-L117 HydrophobicContact CG1-CG 3.82Å; L15-L117 PolarHBondContact O-N 2.93Å; Y16-L117 HydrophobicContact CD2-CB 3.78Å; Y16-L117 HydrophobicContact CD2-CD1 4.3Å; T17-L117 PolarHBondContact N-O 2.92Å; T17-L117 PolarHBondContact OG1-O 2.96Å; I21-L117 HydrophobicContact CD1-CD2 3.84Å; I21-L117 HydrophobicContact CG2-CB 4.31Å; L37-L117 HydrophobicContact CD2-CD1 3.63Å; L80-L117 HydrophobicContact CD1-CD1 4.4Å; V115-L117 HydrophobicContact CG1-CD2 4.25Å; L117-T144 HydrophobicContact CD2-CG2 3.4Å; L117-T144 VanDerWaalsContact CD2-CG2 3.4Å; L117-L161 HydrophobicContact CD2-CD1 3.96Å
118H98.3Very high97.4Very high0 Ų021 Ų210%011%0.11CC..  trans-141.9152.9-165.3-161.3-76.9000111.4M92 I116 L123 T126 T144 G145M92-H118 WeakPolarHBondContact CE-CD2 3.41Å; M92-H118 WeakPolarHBondContact CE-NE2 2.9Å; M92-H118 PolarHBondContact SD-NE2 3.3Å; I116-H118 HydrophobicContact CG2-CB 4.48Å; H118-L123 HydrophobicContact CB-CD1 4.36Å; H118-L123 HydrophobicContact CB-CG 4.46Å; H118-T126 PolarHBondContact CE1-OG1 3.24Å; H118-T126 VanDerWaalsContact CE1-OG1 3.27Å; H118-T126 VanDerWaalsContact NE2-CB 3.32Å; H118-T126 WeakPolarHBondContact NE2-CB 3.48Å; H118-T126 PolarHBondContact NE2-OG1 3.04Å; H118-T144 PolarHBondContact N-O 3Å; H118-G145 WeakPolarHBondContact O-CA 3.15Å
119G96.9Very high97.5Very high2 Ų220.4 Ų20.42%0.02111%0.108CC..  trans-69146.3170.400000111.9S89 D121 L123S89-G119 WeakPolarHBondContact CB-O 3.37Å; S89-G119 VanDerWaalsContact OG-C 3.24Å; S89-G119 WeakPolarHBondContact OG-CA 3.29Å; S89-G119 PolarHBondContact OG-O 3.1Å; G119-D121 PolarHBondContact O-N 3.37Å; G119-L123 WeakPolarHBondContact O-CB 3.39Å
120T97.1Very high97.7Very high4 Ų415.8 Ų15.83%0.0259%0.086CC..SBendtrans-74.1-25.7-169.4560000113T122 L123 S146 Q147 F180 K192 F201T120-T122 PolarHBondContact O-N 3.21Å; T120-L123 PolarHBondContact O-N 3.44Å; T120-S146 WeakPolarHBondContact CG2-O 3.49Å; T120-Q147 PolarHBondContact OG1-OE1 2.95Å; T120-F180 HydrophobicContact CG2-CE2 4.05Å; T120-F180 HydrophobicContact CG2-CZ 4.23Å; T120-K192 WeakPolarHBondContact O-CD 3.31Å; T120-K192 PolarHBondContact OG1-NZ 2.93Å; T120-F201 HydrophobicContact CG2-CE2 4.1Å; T120-F201 HydrophobicContact CG2-CZ 4.09Å
121D96.2Very high98Very high81 Ų8112.4 Ų12.443%0.4336%0.062SC..THydrogen-bonded Turntrans-63-40-171.1-62.9-31.3000114.4S89 G119 K192S89-D121 WeakPolarHBondContact OG-CB 3.45Å; S89-D121 PolarHBondContact OG-N 2.91Å; G119-D121 PolarHBondContact O-N 3.37Å; D121-K192 IonicContact OD1-NZ 3.4Å; D121-K192 PolarHBondContact OD1-NZ 2.92Å
122T97.6Very high98.1Very high29 Ų2911.1 Ų11.118%0.1786%0.057CC..THydrogen-bonded Turntrans-115.614.6177.967.80000113.4S89 T120 C124 Y125 T126S89-T122 VanDerWaalsContact CB-OG1 3.29Å; S89-T122 WeakPolarHBondContact CB-OG1 3.41Å; S89-T122 VanDerWaalsContact O-CG2 3.28Å; S89-T122 WeakPolarHBondContact O-CG2 3.37Å; S89-T122 PolarHBondContact O-OG1 2.92Å; S89-T122 PolarHBondContact OG-N 3.5Å; T120-T122 PolarHBondContact O-N 3.21Å; T122-C124 VanDerWaalsContact C-N 3.3Å; T122-C124 PolarHBondContact O-N 3.41Å; T122-Y125 WeakPolarHBondContact O-CB 3.08Å; T122-Y125 PolarHBondContact O-N 3.3Å; T122-T126 PolarHBondContact O-N 2.59Å
123L98.3Very high98.2Very high0 Ų09.6 Ų9.60%05%0.049CC..Hα-helixtrans-55.1-43.4-176.8-165.3153.2000112.4H118 G119 T120 Y125 T126 A127 L143 I178 F201H118-L123 HydrophobicContact CB-CD1 4.36Å; H118-L123 HydrophobicContact CB-CG 4.46Å; G119-L123 WeakPolarHBondContact O-CB 3.39Å; T120-L123 PolarHBondContact O-N 3.44Å; L123-Y125 VanDerWaalsContact C-N 3.34Å; L123-Y125 PolarHBondContact O-N 3.1Å; L123-T126 PolarHBondContact O-N 3.15Å; L123-A127 WeakPolarHBondContact O-CB 3.33Å; L123-A127 PolarHBondContact O-N 3.1Å; L123-L143 HydrophobicContact CD2-CB 4.11Å; L123-L143 HydrophobicContact CG-CB 4.44Å; L123-I178 HydrophobicContact CD2-CB 4.15Å; L123-I178 HydrophobicContact CD2-CD1 3.25Å; L123-I178 HydrophobicContact CD2-CG1 3.39Å; L123-I178 HydrophobicContact CD2-CG2 3.66Å; L123-F201 HydrophobicContact CB-CE1 4.01Å; L123-F201 HydrophobicContact CB-CZ 3.82Å; L123-F201 HydrophobicContact CD1-CE2 4.26Å; L123-F201 HydrophobicContact CD1-CZ 3.89Å; L123-F201 HydrophobicContact CD2-CE1 4.25Å; L123-F201 HydrophobicContact CD2-CZ 4.13Å; L123-F201 HydrophobicContact CG-CZ 4.18Å
124C98.5Very high98.2Very high3 Ų39.7 Ų9.72%0.025%0.05CC..Hα-helixtrans-65-34.2177.9-62.60000113T122 S128 T190 T191 F201 E351T122-C124 VanDerWaalsContact C-N 3.3Å; T122-C124 PolarHBondContact O-N 3.41Å; C124-S128 VanDerWaalsContact O-CB 3.27Å; C124-S128 WeakPolarHBondContact O-CB 3.38Å; C124-S128 PolarHBondContact O-N 2.93Å; C124-S128 PolarHBondContact O-OG 3.07Å; C124-T190 PolarHBondContact SG-OG1 3.38Å; C124-T191 VanDerWaalsContact SG-C 3.58Å; C124-T191 VanDerWaalsContact SG-CA 3.58Å; C124-F201 WeakPolarHBondContact SG-CD1 3.3Å; C124-F201 VanDerWaalsContact SG-CE1 3.53Å; C124-E351 HydrophobicContact CB-CB 4.33Å; C124-E351 HydrophobicContact CB-CG 3.83Å
125Y98.5Very high98.1Very high73 Ų7310.7 Ų10.729%0.2865%0.054SC..Hα-helixtrans-67.8-47.5174.4-71.2-87.1000110.9T122 L123 A127 S128 A129 E351 L354T122-Y125 WeakPolarHBondContact O-CB 3.08Å; T122-Y125 PolarHBondContact O-N 3.3Å; L123-Y125 VanDerWaalsContact C-N 3.34Å; L123-Y125 PolarHBondContact O-N 3.1Å; Y125-A127 PolarHBondContact O-N 3.39Å; Y125-S128 PolarHBondContact O-N 3.34Å; Y125-A129 WeakPolarHBondContact O-CB 3.25Å; Y125-A129 PolarHBondContact O-N 2.87Å; Y125-E351 HydrophobicContact CD1-CB 4.03Å; Y125-E351 HydrophobicContact CD1-CG 4Å; Y125-E351 HydrophobicContact CD2-CG 3.82Å; Y125-E351 HydrophobicContact CE1-CB 4.18Å; Y125-E351 HydrophobicContact CE1-CG 3.88Å; Y125-E351 HydrophobicContact CE2-CG 3.69Å; Y125-E351 HydrophobicContact CG-CB 4.25Å; Y125-E351 HydrophobicContact CG-CG 3.98Å; Y125-L354 HydrophobicContact CE1-CD1 3.87Å
126T98.7Very high97.8Very high0 Ų012.2 Ų12.20%06%0.062CC..Hα-helixtrans-62.4-44.4177.3-57.40000111.4W97 I100 H118 T122 L123 S128 A129 L130 L143W97-T126 PolarHBondContact NE1-OG1 3.38Å; I100-T126 HydrophobicContact CD1-CG2 4.19Å; H118-T126 PolarHBondContact CE1-OG1 3.24Å; H118-T126 VanDerWaalsContact CE1-OG1 3.27Å; H118-T126 VanDerWaalsContact NE2-CB 3.32Å; H118-T126 WeakPolarHBondContact NE2-CB 3.48Å; H118-T126 PolarHBondContact NE2-OG1 3.04Å; T122-T126 PolarHBondContact O-N 2.59Å; L123-T126 PolarHBondContact O-N 3.15Å; T126-S128 VanDerWaalsContact C-N 3.31Å; T126-S128 PolarHBondContact O-N 2.93Å; T126-A129 PolarHBondContact O-N 2.99Å; T126-L130 HydrophobicContact CG2-CD1 3.85Å; T126-L130 HydrophobicContact CG2-CG 4.24Å; T126-L130 WeakPolarHBondContact O-CB 3.44Å; T126-L130 VanDerWaalsContact O-CG 3.29Å; T126-L130 WeakPolarHBondContact O-CG 3.27Å; T126-L130 PolarHBondContact O-N 2.97Å; T126-L143 HydrophobicContact CG2-CD2 3.83Å
127A98.8Very high97.7Very high0 Ų013.1 Ų13.10%07%0.067CC..Hα-helixtrans-59.5-43.117600000111.7L123 Y125 S131 L143 V176 I178L123-A127 WeakPolarHBondContact O-CB 3.33Å; L123-A127 PolarHBondContact O-N 3.1Å; Y125-A127 PolarHBondContact O-N 3.39Å; A127-S131 VanDerWaalsContact O-CB 3.28Å; A127-S131 WeakPolarHBondContact O-CB 3.23Å; A127-S131 PolarHBondContact O-N 2.82Å; A127-L143 HydrophobicContact CB-CD1 3.83Å; A127-L143 HydrophobicContact CB-CD2 3.98Å; A127-L143 HydrophobicContact CB-CG 4.41Å; A127-V176 HydrophobicContact CB-CG1 4.34Å; A127-V176 WeakPolarHBondContact O-CG1 3.27Å; A127-I178 HydrophobicContact CB-CD1 3.74Å; A127-I178 HydrophobicContact CB-CG1 3.87Å
128S98.7Very high97.5Very high0 Ų013.7 Ų13.70%07%0.073CC..Hα-helixtrans-67.2-42.9177.4-58.60000112.1C124 Y125 T126 S131 F132 T355C124-S128 VanDerWaalsContact O-CB 3.27Å; C124-S128 WeakPolarHBondContact O-CB 3.38Å; C124-S128 PolarHBondContact O-N 2.93Å; C124-S128 PolarHBondContact O-OG 3.07Å; Y125-S128 PolarHBondContact O-N 3.34Å; T126-S128 VanDerWaalsContact C-N 3.31Å; T126-S128 PolarHBondContact O-N 2.93Å; S128-S131 WeakPolarHBondContact O-CB 3.22Å; S128-S131 PolarHBondContact O-N 3.09Å; S128-F132 WeakPolarHBondContact O-CD2 3.48Å; S128-F132 PolarHBondContact O-N 3.25Å; S128-T355 WeakPolarHBondContact CB-OG1 3.36Å; S128-T355 PolarHBondContact O-OG1 3.29Å
129A98.6Very high97.4Very high1 Ų113.9 Ų13.91%0.0087%0.074CC..Hα-helixtrans-61.9-52.8178.300000111.3W97 Y125 T126 S131 F132 M133 L238 T355W97-A129 HydrophobicContact CD2-CB 3.56Å; W97-A129 HydrophobicContact CE3-CB 3.45Å; W97-A129 VanDerWaalsContact CE3-CB 3.45Å; W97-A129 HydrophobicContact CG-CB 4.11Å; W97-A129 HydrophobicContact CH2-CB 4.21Å; W97-A129 HydrophobicContact CZ2-CB 4.3Å; W97-A129 HydrophobicContact CZ3-CB 3.8Å; Y125-A129 WeakPolarHBondContact O-CB 3.25Å; Y125-A129 PolarHBondContact O-N 2.87Å; T126-A129 PolarHBondContact O-N 2.99Å; A129-S131 PolarHBondContact O-N 3.41Å; A129-F132 PolarHBondContact O-N 3.41Å; A129-F132 VanDerWaalsContact O-N 3.1Å; A129-M133 VanDerWaalsContact O-CG 3.23Å; A129-M133 WeakPolarHBondContact O-CG 3.47Å; A129-M133 PolarHBondContact O-N 3.17Å; A129-L238 HydrophobicContact CB-CD1 4.41Å; A129-T355 HydrophobicContact CB-CG2 3.83Å
130L98.7Very high97.4Very high0 Ų013.9 Ų13.90%07%0.074CC..Hα-helixtrans-60.2-37178.3-64.6174.7000111.3I100 A101 I116 T126 F132 M133 F134 V176I100-L130 HydrophobicContact CB-CD2 4.35Å; I100-L130 HydrophobicContact CG2-CD1 3.86Å; I100-L130 HydrophobicContact CG2-CD2 4.04Å; A101-L130 HydrophobicContact CB-CD2 4.01Å; I116-L130 HydrophobicContact CD1-CD1 3.41Å; I116-L130 VanDerWaalsContact CD1-CD1 3.41Å; T126-L130 HydrophobicContact CG2-CD1 3.85Å; T126-L130 HydrophobicContact CG2-CG 4.24Å; T126-L130 WeakPolarHBondContact O-CB 3.44Å; T126-L130 VanDerWaalsContact O-CG 3.29Å; T126-L130 WeakPolarHBondContact O-CG 3.27Å; T126-L130 PolarHBondContact O-N 2.97Å; L130-F132 VanDerWaalsContact C-N 3.28Å; L130-F132 PolarHBondContact O-N 3.45Å; L130-M133 HydrophobicContact CD2-SD 4.14Å; L130-M133 PolarHBondContact O-N 3.22Å; L130-F134 HydrophobicContact CB-CD2 4.42Å; L130-F134 HydrophobicContact CD2-CE2 4.17Å; L130-F134 WeakPolarHBondContact O-CD2 3.46Å; L130-F134 PolarHBondContact O-N 2.92Å; L130-V176 HydrophobicContact CB-CG1 4.14Å; L130-V176 HydrophobicContact CB-CG2 4.18Å
131S98.6Very high97.5Very high9 Ų913.7 Ų13.76%0.0637%0.072CC..Hα-helixtrans-57.2-39.1176.4-176.80000113.1A127 S128 A129 N188 R380A127-S131 VanDerWaalsContact O-CB 3.28Å; A127-S131 WeakPolarHBondContact O-CB 3.23Å; A127-S131 PolarHBondContact O-N 2.82Å; S128-S131 WeakPolarHBondContact O-CB 3.22Å; S128-S131 PolarHBondContact O-N 3.09Å; A129-S131 PolarHBondContact O-N 3.41Å; S131-N188 PolarHBondContact OG-ND2 3.48Å; S131-R380 VanDerWaalsContact O-CD 3.23Å; S131-R380 WeakPolarHBondContact O-CD 3.03Å; S131-R380 WeakPolarHBondContact O-CG 2.84Å; S131-R380 PolarHBondContact O-NE 3.27Å
132F98.2Very high97.7Very high0 Ų09.9 Ų9.90%05%0.052CC..Hα-helixtrans-82.2-35175.8-63.1-63.7000113.1S128 A129 L130 F134 A352 T355 K356 Y359 I379 R380 E382S128-F132 WeakPolarHBondContact O-CD2 3.48Å; S128-F132 PolarHBondContact O-N 3.25Å; A129-F132 PolarHBondContact O-N 3.41Å; A129-F132 VanDerWaalsContact O-N 3.1Å; L130-F132 VanDerWaalsContact C-N 3.28Å; L130-F132 PolarHBondContact O-N 3.45Å; F132-F134 VanDerWaalsContact C-N 3.34Å; F132-F134 PolarHBondContact O-N 3.27Å; F132-A352 WeakPolarHBondContact CE2-O 3.33Å; F132-T355 WeakPolarHBondContact CD2-OG1 3.48Å; F132-T355 VanDerWaalsContact CE2-OG1 3.29Å; F132-T355 WeakPolarHBondContact CE2-OG1 3.46Å; F132-K356 HydrophobicContact CD1-CB 4.48Å; F132-K356 HydrophobicContact CD1-CG 4.28Å; F132-K356 HydrophobicContact CD2-CB 4.16Å; F132-K356 HydrophobicContact CE1-CB 3.95Å; F132-K356 HydrophobicContact CE1-CD 4.02Å; F132-K356 HydrophobicContact CE1-CG 3.75Å; F132-K356 HydrophobicContact CE2-CB 3.6Å; F132-K356 HydrophobicContact CE2-CG 4.33Å; F132-K356 HydrophobicContact CZ-CB 3.49Å; F132-K356 VanDerWaalsContact CZ-CB 3.49Å; F132-K356 HydrophobicContact CZ-CD 4.03Å; F132-K356 HydrophobicContact CZ-CG 3.81Å; F132-Y359 HydrophobicContact CB-CD1 4.25Å; F132-Y359 HydrophobicContact CB-CD2 4.03Å; F132-Y359 HydrophobicContact CB-CG 3.77Å; F132-Y359 HydrophobicContact CG-CG 4.49Å; F132-Y359 WeakPolarHBondContact O-CD2 3.18Å; F132-Y359 WeakPolarHBondContact O-CE2 3.27Å; F132-I379 HydrophobicContact CD1-CD1 3.65Å; F132-I379 HydrophobicContact CD1-CG1 4.07Å; F132-I379 HydrophobicContact CE1-CD1 3.75Å; F132-I379 HydrophobicContact CE1-CG1 3.78Å; F132-R380 HydrophobicContact CD1-CB 4.37Å; F132-R380 HydrophobicContact CD1-CG 3.8Å; F132-R380 HydrophobicContact CE1-CB 4.15Å; F132-R380 HydrophobicContact CE1-CG 4.06Å; F132-E382 HydrophobicContact CE1-CG 4.12Å; F132-E382 HydrophobicContact CZ-CB 4.06Å; F132-E382 HydrophobicContact CZ-CG 3.83Å
133M98.3Very high97.7Very high0 Ų08.5 Ų8.50%04%0.043CC..Hα-helixtrans-63.4-38.6179.1-68.9172.675.200112.4W97 A101 A129 L130 E135 V234 R235 L238W97-M133 HydrophobicContact CB-SD 4.01Å; A101-M133 HydrophobicContact CB-CE 3.46Å; A101-M133 VanDerWaalsContact CB-CE 3.46Å; A101-M133 HydrophobicContact CB-SD 4.37Å; A129-M133 VanDerWaalsContact O-CG 3.23Å; A129-M133 WeakPolarHBondContact O-CG 3.47Å; A129-M133 PolarHBondContact O-N 3.17Å; L130-M133 HydrophobicContact CD2-SD 4.14Å; L130-M133 PolarHBondContact O-N 3.22Å; M133-E135 PolarHBondContact O-N 3.19Å; M133-V234 CarbonylContact O-C 3.34Å; M133-V234 WeakPolarHBondContact O-CA 3.37Å; M133-R235 WeakPolarHBondContact CG-O 3.23Å; M133-R235 PolarHBondContact O-N 2.84Å; M133-L238 HydrophobicContact CG-CD1 3.93Å; M133-L238 HydrophobicContact CG-CD2 4.05Å; M133-L238 HydrophobicContact CG-CG 4.13Å; M133-L238 HydrophobicContact SD-CD1 3.83Å; M133-L238 HydrophobicContact SD-CG 4.45Å
134F97.7Very high97.7Very high2 Ų28.5 Ų8.51%0.0094%0.043CC..EExtended strand (participates in β ladder)trans-85.4106.9175.5-75.8-89.6000110.6A101 I104 L130 F132 L137 I141 V232 V234 R380A101-F134 HydrophobicContact CB-CE2 3.75Å; A101-F134 HydrophobicContact CB-CZ 4.03Å; A101-F134 WeakPolarHBondContact O-CZ 3.33Å; I104-F134 HydrophobicContact CB-CE1 4.36Å; I104-F134 HydrophobicContact CB-CZ 3.77Å; I104-F134 HydrophobicContact CD1-CZ 4.38Å; I104-F134 HydrophobicContact CG2-CE1 3.72Å; I104-F134 HydrophobicContact CG2-CZ 3.57Å; L130-F134 HydrophobicContact CB-CD2 4.42Å; L130-F134 HydrophobicContact CD2-CE2 4.17Å; L130-F134 WeakPolarHBondContact O-CD2 3.46Å; L130-F134 PolarHBondContact O-N 2.92Å; F132-F134 VanDerWaalsContact C-N 3.34Å; F132-F134 PolarHBondContact O-N 3.27Å; F134-L137 HydrophobicContact CB-CB 4.28Å; F134-L137 HydrophobicContact CB-CD1 4.37Å; F134-L137 HydrophobicContact CD1-CD1 4.09Å; F134-L137 HydrophobicContact CG-CD1 4.39Å; F134-I141 HydrophobicContact CD1-CD1 4.15Å; F134-I141 HydrophobicContact CD2-CD1 3.89Å; F134-I141 HydrophobicContact CE1-CD1 4.17Å; F134-I141 HydrophobicContact CE2-CD1 3.91Å; F134-I141 HydrophobicContact CG-CD1 4.03Å; F134-I141 HydrophobicContact CZ-CD1 4.06Å; F134-V232 HydrophobicContact CD1-CG2 3.81Å; F134-V234 HydrophobicContact CD1-CG2 3.58Å; F134-V234 HydrophobicContact CE1-CG2 3.41Å; F134-V234 VanDerWaalsContact CE1-CG2 3.41Å; F134-V234 HydrophobicContact CG-CG2 4.37Å; F134-V234 HydrophobicContact CZ-CG1 4.43Å; F134-V234 HydrophobicContact CZ-CG2 4.08Å; F134-R380 PolarHBondContact O-NE 3.26Å; F134-R380 VanDerWaalsContact O-NE 3.12Å
135E95.6Very high97.7Very high21 Ų218.3 Ų8.310%0.0984%0.042CC..EExtended strand (participates in β ladder)trans-89.7141.2167.5-35.4-159.6144.500109.7M133 L137 V232 F233 R235 Y359 R363 R380M133-E135 PolarHBondContact O-N 3.19Å; E135-L137 PolarHBondContact O-N 3.19Å; E135-V232 WeakPolarHBondContact O-CA 3.28Å; E135-V232 WeakPolarHBondContact O-CG2 3.35Å; E135-F233 HydrophobicContact CB-CB 4.31Å; E135-F233 HydrophobicContact CG-CD1 4.06Å; E135-F233 PolarHBondContact N-O 2.94Å; E135-F233 PolarHBondContact O-N 3.43Å; E135-F233 WeakPolarHBondContact OE2-CD1 3.48Å; E135-R235 VanDerWaalsContact CD-NE 3.29Å; E135-R235 HydrophobicContact CG-CG 4.48Å; E135-R235 WeakPolarHBondContact OE1-CD 3.3Å; E135-R235 IonicContact OE1-CZ 3.7Å; E135-R235 IonicContact OE1-NE 2.67Å; E135-R235 PolarHBondContact OE1-NE 2.95Å; E135-R235 IonicContact OE1-NH2 3Å; E135-R235 PolarHBondContact OE1-NH2 3.03Å; E135-R235 IonicContact OE2-CZ 2.69Å; E135-R235 IonicContact OE2-NE 2.68Å; E135-R235 PolarHBondContact OE2-NE 2.88Å; E135-R235 IonicContact OE2-NH2 2.7Å; E135-R235 PolarHBondContact OE2-NH2 3.34Å; E135-Y359 WeakPolarHBondContact OE1-CE2 3.39Å; E135-Y359 PolarHBondContact OE1-OH 3.28Å; E135-R363 IonicContact OE1-NH1 3.84Å; E135-R380 VanDerWaalsContact CA-NH2 3.34Å; E135-R380 VanDerWaalsContact CG-NH2 3.31Å; E135-R380 IonicContact OE1-NH2 3.36Å
136D93.8Very high97.6Very high31 Ų314.9 Ų4.917%0.1663%0.029CC..SBendtrans53.938.5177.9-49.9-44.1000112.9G138 S226 V228 S230D136-G138 PolarHBondContact O-N 2.94Å; D136-S226 WeakPolarHBondContact OD1-CB 3.38Å; D136-S226 PolarHBondContact OD1-OG 2.85Å; D136-V228 WeakPolarHBondContact OD1-CB 3.46Å; D136-S230 WeakPolarHBondContact CB-OG 3.21Å; D136-S230 PolarHBondContact OD2-OG 3.05Å
137L95.7Very high97.4Very high19 Ų196.5 Ų6.510%0.0994%0.036CC..  trans-55.3131.5172.6-17564000109.1Y108 F134 E135 K139 I141 P174 V176 V232Y108-L137 HydrophobicContact CE2-CD1 3.91Å; F134-L137 HydrophobicContact CB-CB 4.28Å; F134-L137 HydrophobicContact CB-CD1 4.37Å; F134-L137 HydrophobicContact CD1-CD1 4.09Å; F134-L137 HydrophobicContact CG-CD1 4.39Å; E135-L137 PolarHBondContact O-N 3.19Å; L137-K139 WeakPolarHBondContact CD1-O 3.28Å; L137-K139 WeakPolarHBondContact CD2-O 3.38Å; L137-K139 VanDerWaalsContact CG-O 3.25Å; L137-K139 WeakPolarHBondContact CG-O 3.48Å; L137-I141 HydrophobicContact CD1-CD1 3.69Å; L137-I141 HydrophobicContact CD1-CG1 4.14Å; L137-I141 HydrophobicContact CD2-CD1 4.01Å; L137-I141 HydrophobicContact CD2-CG1 4.23Å; L137-P174 WeakPolarHBondContact O-CB 3.38Å; L137-V176 HydrophobicContact CD2-CG2 4.02Å; L137-V232 HydrophobicContact CD1-CG2 4.5Å
138G94.5Very high97.2Very high12 Ų128.8 Ų8.812%0.1245%0.048CC..  trans-115.6-7.9179.800000113.7Y108 D136 H481Y108-G138 WeakPolarHBondContact OH-CA 3.45Å; Y108-G138 PolarHBondContact OH-N 3.41Å; D136-G138 PolarHBondContact O-N 2.94Å; G138-H481 PolarHBondContact O-CD2 3.41Å
139K96.3Very high97Very high4 Ų48.9 Ų8.92%0.0175%0.049CC..SBendtrans-130.5153.3-173.6-65.9-178.2-179.2-173.60111.2Y108 Y111 F114 L137 I141 H512Y108-K139 HydrophobicContact CD1-CD 4.39Å; Y108-K139 HydrophobicContact CE1-CD 3.91Å; Y108-K139 HydrophobicContact CE1-CG 4.21Å; Y108-K139 HydrophobicContact CE2-CB 4.13Å; Y108-K139 HydrophobicContact CE2-CD 4.11Å; Y108-K139 HydrophobicContact CE2-CG 4.35Å; Y108-K139 PolarHBondContact O-NZ 3.42Å; Y108-K139 PolarHBondContact OH-N 2.65Å; Y108-K139 VanDerWaalsContact OH-N 3.08Å; Y111-K139 WeakPolarHBondContact O-CD 3.28Å; Y111-K139 PolarHBondContact O-NZ 3.17Å; F114-K139 HydrophobicContact CE2-CB 4.32Å; F114-K139 HydrophobicContact CE2-CD 4.16Å; L137-K139 WeakPolarHBondContact CD1-O 3.28Å; L137-K139 WeakPolarHBondContact CD2-O 3.38Å; L137-K139 VanDerWaalsContact CG-O 3.25Å; L137-K139 WeakPolarHBondContact CG-O 3.48Å; K139-I141 PolarHBondContact O-N 3.38Å; K139-H512 WeakPolarHBondContact CE-CE1 3.15Å; K139-H512 PolarHBondContact NZ-CE1 2.99Å; K139-H512 PolarHBondContact NZ-NE2 3.01Å
140P98.2Very high96.7Very high3 Ų39.2 Ų9.22%0.0195%0.051CC..  trans-66.2131.717727.1-34.9000112.1G113 F114 V142 I173G113-P140 WeakPolarHBondContact CA-O 3.37Å; F114-P140 PolarHBondContact N-O 2.85Å; P140-V142 HydrophobicContact CB-CG2 4.27Å; P140-I173 WeakPolarHBondContact CA-O 3.07Å; P140-I173 VanDerWaalsContact CB-O 3.32Å; P140-I173 WeakPolarHBondContact CB-O 3.31Å
141I98.8Very high96.1Very high0 Ų011.5 Ų11.50%07%0.066CC..EExtended strand (participates in β ladder)trans-116.6109.8163.8-60.3173.8000106.7I104 F114 I116 F134 L137 K139 E175 V176 T177I104-I141 HydrophobicContact CD1-CD1 4.09Å; I104-I141 HydrophobicContact CD1-CG1 4.37Å; I104-I141 HydrophobicContact CD1-CG2 4.01Å; I104-I141 HydrophobicContact CG2-CD1 4.11Å; F114-I141 HydrophobicContact CB-CG1 4.22Å; F114-I141 HydrophobicContact CD2-CG1 4Å; F114-I141 HydrophobicContact CG-CG1 4.44Å; F114-I141 CarbonylContact O-C 3.54Å; F114-I141 WeakPolarHBondContact O-CA 3.47Å; I116-I141 HydrophobicContact CD1-CG2 3.64Å; I116-I141 HydrophobicContact CG1-CG2 4.43Å; F134-I141 HydrophobicContact CD1-CD1 4.15Å; F134-I141 HydrophobicContact CD2-CD1 3.89Å; F134-I141 HydrophobicContact CE1-CD1 4.17Å; F134-I141 HydrophobicContact CE2-CD1 3.91Å; F134-I141 HydrophobicContact CG-CD1 4.03Å; F134-I141 HydrophobicContact CZ-CD1 4.06Å; L137-I141 HydrophobicContact CD1-CD1 3.69Å; L137-I141 HydrophobicContact CD1-CG1 4.14Å; L137-I141 HydrophobicContact CD2-CD1 4.01Å; L137-I141 HydrophobicContact CD2-CG1 4.23Å; K139-I141 PolarHBondContact O-N 3.38Å; I141-E175 PolarHBondContact N-O 3.38Å; I141-E175 VanDerWaalsContact N-O 3.12Å; I141-V176 HydrophobicContact CB-CG2 4.14Å; I141-V176 HydrophobicContact CD1-CG2 4.19Å; I141-V176 HydrophobicContact CG2-CG1 4.4Å; I141-V176 HydrophobicContact CG2-CG2 4.44Å; I141-V176 CarbonylContact O-C 3.55Å; I141-V176 WeakPolarHBondContact O-CA 3.44Å; I141-T177 PolarHBondContact O-N 2.91Å; I141-T177 PolarHBondContact O-OG1 3.47Å
142V98.9Very high95.7Very high0 Ų014.4 Ų14.40%08%0.079CC..EExtended strand (participates in β ladder)trans-110110.3-173.9-169.20000109.7F114 V115 I116 P140 I167 A168 C179 L184F114-V142 PolarHBondContact O-N 3.2Å; V115-V142 CarbonylContact C-O 3.5Å; V115-V142 WeakPolarHBondContact CA-O 3.46Å; V115-V142 HydrophobicContact CG2-CB 4.42Å; I116-V142 PolarHBondContact N-O 3.15Å; P140-V142 HydrophobicContact CB-CG2 4.27Å; V142-I167 HydrophobicContact CG2-CB 4.25Å; V142-I167 HydrophobicContact CG2-CG2 3.77Å; V142-A168 HydrophobicContact CG2-CB 4.11Å; V142-C179 HydrophobicContact CG1-CB 3.46Å; V142-C179 VanDerWaalsContact CG1-CB 3.46Å; V142-L184 HydrophobicContact CG1-CD1 4.28Å
143L98.9Very high95.3Very high0 Ų021.2 Ų21.20%012%0.12CC..EExtended strand (participates in β ladder)trans-81.1144169.3-66.789.4000109.8I116 L123 T126 A127 V176 T177 I178 C179I116-L143 HydrophobicContact CB-CG 4.18Å; I116-L143 HydrophobicContact CD1-CD1 4.33Å; I116-L143 HydrophobicContact CD1-CG 4.07Å; I116-L143 WeakPolarHBondContact O-CA 3.25Å; L123-L143 HydrophobicContact CD2-CB 4.11Å; L123-L143 HydrophobicContact CG-CB 4.44Å; T126-L143 HydrophobicContact CG2-CD2 3.83Å; A127-L143 HydrophobicContact CB-CD1 3.83Å; A127-L143 HydrophobicContact CB-CD2 3.98Å; A127-L143 HydrophobicContact CB-CG 4.41Å; L143-V176 HydrophobicContact CD1-CG1 3.29Å; L143-T177 WeakPolarHBondContact CD1-O 3.22Å; L143-T177 PolarHBondContact N-O 2.72Å; L143-I178 HydrophobicContact CB-CG1 4.21Å; L143-I178 WeakPolarHBondContact O-CA 3.44Å; L143-C179 PolarHBondContact O-N 2.69Å
144T98.6Very high95Very high0 Ų030.6 Ų30.60%016%0.156CC..EExtended strand (participates in β ladder)trans-154.9172171.7-163.30000110.9V115 I116 L117 H118 N160 S164 C179V115-T144 HydrophobicContact CG1-CG2 4.17Å; I116-T144 PolarHBondContact O-N 3.15Å; L117-T144 HydrophobicContact CD2-CG2 3.4Å; L117-T144 VanDerWaalsContact CD2-CG2 3.4Å; H118-T144 PolarHBondContact N-O 3Å; T144-N160 WeakPolarHBondContact OG1-CB 3.42Å; T144-S164 WeakPolarHBondContact CB-OG 3.49Å; T144-S164 VanDerWaalsContact CG2-OG 3.3Å; T144-S164 WeakPolarHBondContact CG2-OG 3.49Å; T144-C179 WeakPolarHBondContact CB-O 3.46Å; T144-C179 PolarHBondContact OG1-O 2.74Å
145G97.1Very high94.8Very high0 Ų031.5 Ų31.50%016%0.162CC..  trans-165.4-159.5178.800000109.6H118 N160 F180H118-G145 WeakPolarHBondContact O-CA 3.15Å; G145-N160 PolarHBondContact O-ND2 3.27Å; G145-F180 WeakPolarHBondContact O-CE2 3.32Å
146S96.8Very high94.8Very high1 Ų131 Ų311%0.00716%0.16CC..  trans-152.7159.3172.272.90000111.2T20 I21 T120 I148 D156 G157T20-S146 WeakPolarHBondContact CB-O 3.34Å; I21-S146 WeakPolarHBondContact CA-OG 3.25Å; I21-S146 WeakPolarHBondContact CB-OG 3.48Å; I21-S146 PolarHBondContact N-OG 3.47Å; T120-S146 WeakPolarHBondContact CG2-O 3.49Å; S146-I148 VanDerWaalsContact CB-O 3.27Å; S146-I148 WeakPolarHBondContact CB-O 3.19Å; S146-I148 PolarHBondContact OG-O 2.81Å; S146-D156 VanDerWaalsContact CA-OD2 3.28Å; S146-D156 WeakPolarHBondContact CA-OD2 3.28Å; S146-D156 WeakPolarHBondContact CB-OD1 3.08Å; S146-G157 VanDerWaalsContact CB-CA 3.41Å
147Q95.4Very high94.9Very high33 Ų3329.5 Ų29.515%0.15415%0.152CC..SBendtrans-86-25.8169.5-62.9-70.772.500111.2T20 T120 D156 F180 C195 G197 L198 A200T20-Q147 WeakPolarHBondContact CG2-O 3.35Å; T120-Q147 PolarHBondContact OG1-OE1 2.95Å; Q147-D156 PolarHBondContact N-OD1 2.87Å; Q147-D156 VanDerWaalsContact N-OD1 3.13Å; Q147-D156 PolarHBondContact N-OD2 3.06Å; Q147-F180 HydrophobicContact CG-CE1 4.43Å; Q147-F180 HydrophobicContact CG-CZ 4.13Å; Q147-C195 PolarHBondContact NE2-O 3.14Å; Q147-G197 PolarHBondContact NE2-O 3.35Å; Q147-L198 HydrophobicContact CB-CD2 4.18Å; Q147-A200 HydrophobicContact CG-CB 4.34Å
148I94.4Very high94.8Very high48 Ų4832.6 Ų32.625%0.24616%0.162CC..SBendtrans-123134.2178.4-52.2171.1000109.2S146 E152 R154 C155 D156 L198S146-I148 VanDerWaalsContact CB-O 3.27Å; S146-I148 WeakPolarHBondContact CB-O 3.19Å; S146-I148 PolarHBondContact OG-O 2.81Å; I148-E152 HydrophobicContact CG2-CB 3.71Å; I148-E152 HydrophobicContact CG2-CG 3.84Å; I148-R154 WeakPolarHBondContact CD1-O 3.31Å; I148-R154 VanDerWaalsContact CG2-O 3.32Å; I148-R154 WeakPolarHBondContact CG2-O 3.48Å; I148-C155 HydrophobicContact CB-CB 4.3Å; I148-C155 HydrophobicContact CG2-CB 4.24Å; I148-D156 PolarHBondContact N-OD1 3.49Å; I148-L198 HydrophobicContact CD1-CD2 4.38Å
149P93.6Very high94.8Very high2 Ų238.3 Ų38.31%0.01319%0.186CC..  trans-56.8147179.4-23.232.6000112.9T20 M23 Y30 S151 E152 C155T20-P149 HydrophobicContact CG2-CG 3.92Å; T20-P149 VanDerWaalsContact O-CA 3.25Å; T20-P149 WeakPolarHBondContact O-CA 3.36Å; T20-P149 VanDerWaalsContact O-CB 3.29Å; T20-P149 WeakPolarHBondContact O-CB 3.13Å; T20-P149 WeakPolarHBondContact O-CG 3.27Å; M23-P149 WeakPolarHBondContact O-CB 3.45Å; Y30-P149 HydrophobicContact CD1-CG 3.66Å; Y30-P149 HydrophobicContact CE1-CG 3.56Å; Y30-P149 HydrophobicContact CG-CG 4.31Å; P149-S151 PolarHBondContact O-N 3.25Å; P149-S151 VanDerWaalsContact O-N 3.14Å; P149-E152 HydrophobicContact CB-CG 4.37Å; P149-E152 HydrophobicContact CG-CG 4.46Å; P149-E152 WeakPolarHBondContact O-CB 3.47Å; P149-E152 PolarHBondContact O-N 3.01Å; P149-E152 VanDerWaalsContact O-N 3.13Å; P149-C155 WeakPolarHBondContact O-CB 3.49Å
150I92.6Very high94.9Very high9 Ų938.4 Ų38.45%0.04619%0.186CC..THydrogen-bonded Turntrans-64.9-22.3-174.4-156.1167.8000113.4I21 L37 A40 L47 E152 R158 L161I21-I150 HydrophobicContact CG1-CB 4.3Å; I21-I150 WeakPolarHBondContact O-CB 3.49Å; I21-I150 WeakPolarHBondContact O-CG2 3.39Å; I21-I150 PolarHBondContact O-N 3.19Å; L37-I150 HydrophobicContact CD1-CB 4.42Å; L37-I150 HydrophobicContact CD1-CG2 3.43Å; L37-I150 VanDerWaalsContact CD1-CG2 3.43Å; A40-I150 HydrophobicContact CB-CG2 4.28Å; L47-I150 HydrophobicContact CD1-CD1 3.63Å; I150-E152 VanDerWaalsContact C-N 3.32Å; I150-R158 HydrophobicContact CG1-CB 4.39Å; I150-L161 HydrophobicContact CD1-CD2 4.27Å
151S86.7Confident94.8Very high47 Ų4738.3 Ų38.333%0.32919%0.185SC..THydrogen-bonded Turntrans-77.4-17.5179.753.40000113.8Y36 P149Y36-S151 WeakPolarHBondContact CE1-OG 3.22Å; Y36-S151 WeakPolarHBondContact OH-CB 3.48Å; Y36-S151 PolarHBondContact OH-OG 2.85Å; P149-S151 PolarHBondContact O-N 3.25Å; P149-S151 VanDerWaalsContact O-N 3.14Å
152E89.8Confident94.8Very high71 Ų7140 Ų4033%0.33220%0.196SC..SBendtrans-73.5143.2172.2-61.7-68.217400109.8Y30 I148 P149 I150 R154Y30-E152 PolarHBondContact OH-OE1 2.84Å; I148-E152 HydrophobicContact CG2-CB 3.71Å; I148-E152 HydrophobicContact CG2-CG 3.84Å; P149-E152 HydrophobicContact CB-CG 4.37Å; P149-E152 HydrophobicContact CG-CG 4.46Å; P149-E152 WeakPolarHBondContact O-CB 3.47Å; P149-E152 PolarHBondContact O-N 3.01Å; P149-E152 VanDerWaalsContact O-N 3.13Å; I150-E152 VanDerWaalsContact C-N 3.32Å; E152-R154 VanDerWaalsContact C-N 3.31Å; E152-R154 PolarHBondContact O-N 3.25Å
153V89.2Confident94.7Very high142 Ų14240.1 Ų40.186%0.86120%0.197SC*.SBendtrans-58.9-43.6-176176.60000111.7
154R92.9Very high94.7Very high198 Ų19840.1 Ų40.175%0.74720%0.197SC*.SBendtrans-100.299.5173.5-179.4-176.3175.9-175.5-1.7108.3I148 E152I148-R154 WeakPolarHBondContact CD1-O 3.31Å; I148-R154 VanDerWaalsContact CG2-O 3.32Å; I148-R154 WeakPolarHBondContact CG2-O 3.48Å; E152-R154 VanDerWaalsContact C-N 3.31Å; E152-R154 PolarHBondContact O-N 3.25Å
155C93.2Very high94.7Very high21 Ų2140.1 Ų40.114%0.14220%0.197CC..  trans-134.7150.817766.70000111.2I148 P149I148-C155 HydrophobicContact CB-CB 4.3Å; I148-C155 HydrophobicContact CG2-CB 4.24Å; P149-C155 WeakPolarHBondContact O-CB 3.49Å
156D95.6Very high94.7Very high9 Ų940.9 Ų40.95%0.04820%0.201CC..SBendtrans-88.1-19.8169.758-46.8000112S146 Q147 I148 R158 E159 N160 F180 L198S146-D156 VanDerWaalsContact CA-OD2 3.28Å; S146-D156 WeakPolarHBondContact CA-OD2 3.28Å; S146-D156 WeakPolarHBondContact CB-OD1 3.08Å; Q147-D156 PolarHBondContact N-OD1 2.87Å; Q147-D156 VanDerWaalsContact N-OD1 3.13Å; Q147-D156 PolarHBondContact N-OD2 3.06Å; I148-D156 PolarHBondContact N-OD1 3.49Å; D156-R158 VanDerWaalsContact C-N 3.29Å; D156-R158 PolarHBondContact O-N 2.97Å; D156-E159 PolarHBondContact O-N 3.06Å; D156-N160 WeakPolarHBondContact O-CB 3.49Å; D156-N160 VanDerWaalsContact O-CG 3.27Å; D156-N160 PolarHBondContact O-N 3.09Å; D156-N160 PolarHBondContact O-ND2 3.27Å; D156-N160 PolarHBondContact OD2-ND2 2.93Å; D156-F180 WeakPolarHBondContact OD2-CZ 3.24Å; D156-L198 HydrophobicContact CB-CD2 3.94Å
157G94.9Very high94.7Very high0 Ų040.8 Ų40.80%020%0.201CC..Hα-helixtrans-59.3-33.5-17700000114.7S146 L161S146-G157 VanDerWaalsContact CB-CA 3.41Å; G157-L161 VanDerWaalsContact O-CB 3.24Å; G157-L161 WeakPolarHBondContact O-CB 3.14Å; G157-L161 PolarHBondContact O-N 3.45Å
158R95Very high94.9Very high84 Ų8439.3 Ų39.332%0.31719%0.194SC..Hα-helixtrans-64-53.9177.2-175.8-172.5-70.81244.3111.2D44 S46 L47 I150 D156 N160 L161 V162D44-R158 IonicContact OD2-CZ 3.65Å; D44-R158 IonicContact OD2-NE 2.72Å; D44-R158 PolarHBondContact OD2-NE 3.17Å; D44-R158 IonicContact OD2-NH2 3.23Å; D44-R158 PolarHBondContact OD2-NH2 3.01Å; S46-R158 VanDerWaalsContact OG-CD 3.31Å; S46-R158 WeakPolarHBondContact OG-CD 3.3Å; S46-R158 PolarHBondContact OG-NE 3.28Å; L47-R158 HydrophobicContact CD1-CG 4.49Å; L47-R158 HydrophobicContact CD2-CG 4.19Å; L47-R158 HydrophobicContact CG-CG 4.42Å; I150-R158 HydrophobicContact CG1-CB 4.39Å; D156-R158 VanDerWaalsContact C-N 3.29Å; D156-R158 PolarHBondContact O-N 2.97Å; R158-N160 PolarHBondContact O-N 2.85Å; R158-L161 PolarHBondContact O-N 2.72Å; R158-V162 VanDerWaalsContact O-CG2 3.3Å; R158-V162 WeakPolarHBondContact O-CG2 3.23Å; R158-V162 PolarHBondContact O-N 2.99Å
159E94.6Very high94.9Very high133 Ų13337.4 Ų37.462%0.62119%0.186SC*.Hα-helixtrans-64.3-42.3-178.6-65.9-173.1161.500111.4D156 L161 V162 G163D156-E159 PolarHBondContact O-N 3.06Å; E159-L161 PolarHBondContact O-N 2.98Å; E159-V162 PolarHBondContact O-N 3.3Å; E159-G163 PolarHBondContact O-N 3.37Å
160N97.4Very high95Very high5 Ų537.6 Ų37.63%0.02719%0.187CC..Hα-helixtrans-59.6-44.6176.6-75-14000112.3T144 G145 D156 R158 S164 F180 N181T144-N160 WeakPolarHBondContact OG1-CB 3.42Å; G145-N160 PolarHBondContact O-ND2 3.27Å; D156-N160 WeakPolarHBondContact O-CB 3.49Å; D156-N160 VanDerWaalsContact O-CG 3.27Å; D156-N160 PolarHBondContact O-N 3.09Å; D156-N160 PolarHBondContact O-ND2 3.27Å; D156-N160 PolarHBondContact OD2-ND2 2.93Å; R158-N160 PolarHBondContact O-N 2.85Å; N160-S164 WeakPolarHBondContact O-CB 3.22Å; N160-S164 PolarHBondContact O-N 3.48Å; N160-S164 PolarHBondContact O-OG 2.88Å; N160-F180 WeakPolarHBondContact ND2-CD2 3.34Å; N160-F180 VanDerWaalsContact ND2-CE2 3.28Å; N160-F180 WeakPolarHBondContact ND2-CE2 3.01Å; N160-F180 WeakPolarHBondContact ND2-CZ 3.46Å; N160-N181 PolarHBondContact OD1-N 2.89Å
161L97.6Very high95.1Very high1 Ų138.8 Ų38.81%0.00519%0.191CC..Hα-helixtrans-66.9-46.9177175.357.1000111.8I41 L47 V115 L117 I150 G157 R158 E159 G163 S164 L165I41-L161 HydrophobicContact CD1-CD2 3.9Å; I41-L161 HydrophobicContact CG1-CD2 4.35Å; L47-L161 HydrophobicContact CD1-CD2 4.3Å; L47-L161 HydrophobicContact CD2-CD2 4.24Å; L47-L161 HydrophobicContact CD2-CG 4.5Å; V115-L161 HydrophobicContact CG1-CD1 4.46Å; L117-L161 HydrophobicContact CD2-CD1 3.96Å; I150-L161 HydrophobicContact CD1-CD2 4.27Å; G157-L161 VanDerWaalsContact O-CB 3.24Å; G157-L161 WeakPolarHBondContact O-CB 3.14Å; G157-L161 PolarHBondContact O-N 3.45Å; R158-L161 PolarHBondContact O-N 2.72Å; E159-L161 PolarHBondContact O-N 2.98Å; L161-G163 VanDerWaalsContact C-N 3.35Å; L161-G163 PolarHBondContact O-N 2.89Å; L161-S164 PolarHBondContact O-N 3.29Å; L161-L165 HydrophobicContact CD1-CD1 3.93Å; L161-L165 HydrophobicContact CD1-CG 3.95Å; L161-L165 HydrophobicContact CG-CD1 4.01Å; L161-L165 HydrophobicContact CG-CG 4.47Å; L161-L165 WeakPolarHBondContact O-CG 3.41Å; L161-L165 PolarHBondContact O-N 3.4Å
162V97Very high95.4Very high35 Ų3537.7 Ų37.721%0.21218%0.181CC..Hα-helixtrans-58.2-48.1177.7171.30000110.7L47 L66 R158 E159 S164 L165 I166L47-V162 HydrophobicContact CD2-CG2 3.46Å; L47-V162 VanDerWaalsContact CD2-CG2 3.46Å; L66-V162 HydrophobicContact CD1-CG1 4.37Å; L66-V162 HydrophobicContact CD1-CG2 4.01Å; L66-V162 HydrophobicContact CD2-CG1 4.43Å; R158-V162 VanDerWaalsContact O-CG2 3.3Å; R158-V162 WeakPolarHBondContact O-CG2 3.23Å; R158-V162 PolarHBondContact O-N 2.99Å; E159-V162 PolarHBondContact O-N 3.3Å; V162-S164 VanDerWaalsContact C-N 3.32Å; V162-S164 PolarHBondContact O-N 3.03Å; V162-L165 PolarHBondContact O-N 3.14Å; V162-I166 HydrophobicContact CG1-CD1 3.76Å; V162-I166 HydrophobicContact CG1-CG1 4.48Å; V162-I166 VanDerWaalsContact O-CG1 3.31Å; V162-I166 WeakPolarHBondContact O-CG1 3.32Å; V162-I166 PolarHBondContact O-N 3.49Å
163G97.3Very high95.7Very high3 Ų334.3 Ų34.33%0.03117%0.165CC..Hα-helixtrans-57.9-44.1176.200000112.4E159 L161 L165 I166 I167 M212E159-G163 PolarHBondContact O-N 3.37Å; L161-G163 VanDerWaalsContact C-N 3.35Å; L161-G163 PolarHBondContact O-N 2.89Å; G163-L165 PolarHBondContact O-N 3.1Å; G163-I166 PolarHBondContact O-N 3.23Å; G163-I167 WeakPolarHBondContact O-CG1 3.34Å; G163-I167 PolarHBondContact O-N 3.48Å; G163-M212 WeakPolarHBondContact CA-SD 3.48Å
164S98.5Very high96Very high0 Ų028.1 Ų28.10%013%0.128CC..Hα-helixtrans-63.4-42.2179.1-57.60000112.5T144 N160 L161 V162 I167 A168 C179T144-S164 WeakPolarHBondContact CB-OG 3.49Å; T144-S164 VanDerWaalsContact CG2-OG 3.3Å; T144-S164 WeakPolarHBondContact CG2-OG 3.49Å; N160-S164 WeakPolarHBondContact O-CB 3.22Å; N160-S164 PolarHBondContact O-N 3.48Å; N160-S164 PolarHBondContact O-OG 2.88Å; L161-S164 PolarHBondContact O-N 3.29Å; V162-S164 VanDerWaalsContact C-N 3.32Å; V162-S164 PolarHBondContact O-N 3.03Å; S164-I167 PolarHBondContact O-N 2.74Å; S164-A168 VanDerWaalsContact O-CB 3.3Å; S164-A168 WeakPolarHBondContact O-CB 3.49Å; S164-A168 PolarHBondContact O-N 2.96Å; S164-C179 VanDerWaalsContact OG-CB 3.3Å; S164-C179 WeakPolarHBondContact OG-CB 3.38Å
165L98.2Very high96.3Very high0 Ų019.1 Ų19.10%010%0.095CC..Hα-helixtrans-65.6-40176.4-71.9171.2000112V12 V14 L66 V76 Y78 V115 L161 V162 G163 G169V12-L165 HydrophobicContact CB-CD2 4.37Å; V12-L165 HydrophobicContact CG1-CD2 3.96Å; V14-L165 HydrophobicContact CG2-CD2 3.85Å; L66-L165 HydrophobicContact CD2-CB 4.49Å; V76-L165 HydrophobicContact CG1-CB 4.22Å; V76-L165 HydrophobicContact CG1-CD2 4.37Å; Y78-L165 HydrophobicContact CD1-CD1 3.94Å; Y78-L165 HydrophobicContact CD1-CD2 4.03Å; Y78-L165 HydrophobicContact CD2-CD1 4.48Å; Y78-L165 HydrophobicContact CD2-CD2 4.14Å; Y78-L165 HydrophobicContact CE1-CD1 3.78Å; Y78-L165 HydrophobicContact CE2-CD1 4.33Å; Y78-L165 HydrophobicContact CG-CD1 4.28Å; Y78-L165 HydrophobicContact CG-CD2 3.73Å; V115-L165 HydrophobicContact CG2-CD2 4.24Å; L161-L165 HydrophobicContact CD1-CD1 3.93Å; L161-L165 HydrophobicContact CD1-CG 3.95Å; L161-L165 HydrophobicContact CG-CD1 4.01Å; L161-L165 HydrophobicContact CG-CG 4.47Å; L161-L165 WeakPolarHBondContact O-CG 3.41Å; L161-L165 PolarHBondContact O-N 3.4Å; V162-L165 PolarHBondContact O-N 3.14Å; G163-L165 PolarHBondContact O-N 3.1Å; L165-G169 PolarHBondContact O-N 2.67Å
166I97.4Very high96.6Very high16 Ų1618.3 Ų18.38%0.0829%0.089CC..Hα-helixtrans-61-50.6175-69.9162.7000110L66 V69 E72 V162 G163 G169 N170 Y171 V216L66-I166 HydrophobicContact CD2-CG1 4.22Å; V69-I166 HydrophobicContact CG1-CD1 3.74Å; V69-I166 HydrophobicContact CG1-CG1 4.23Å; V69-I166 HydrophobicContact CG2-CD1 4.22Å; V69-I166 HydrophobicContact CG2-CG1 4.15Å; E72-I166 HydrophobicContact CG-CG2 4.04Å; V162-I166 HydrophobicContact CG1-CD1 3.76Å; V162-I166 HydrophobicContact CG1-CG1 4.48Å; V162-I166 VanDerWaalsContact O-CG1 3.31Å; V162-I166 WeakPolarHBondContact O-CG1 3.32Å; V162-I166 PolarHBondContact O-N 3.49Å; G163-I166 PolarHBondContact O-N 3.23Å; I166-G169 PolarHBondContact O-N 3.3Å; I166-N170 WeakPolarHBondContact O-CB 3.37Å; I166-N170 PolarHBondContact O-N 2.95Å; I166-Y171 HydrophobicContact CG2-CD2 4.4Å; I166-Y171 HydrophobicContact CG2-CE2 3.84Å; I166-V216 HydrophobicContact CG2-CG2 4.28Å
167I98Very high96.7Very high0 Ų017.9 Ų17.90%09%0.087CC..Hα-helixtrans-60.5-52.1179.3-65.5-60.4000111V142 G163 S164 G169 Y171 I173 L184 M212 V216V142-I167 HydrophobicContact CG2-CB 4.25Å; V142-I167 HydrophobicContact CG2-CG2 3.77Å; G163-I167 WeakPolarHBondContact O-CG1 3.34Å; G163-I167 PolarHBondContact O-N 3.48Å; S164-I167 PolarHBondContact O-N 2.74Å; I167-G169 VanDerWaalsContact C-N 3.26Å; I167-G169 PolarHBondContact O-N 3.2Å; I167-Y171 HydrophobicContact CD1-CD2 3.97Å; I167-Y171 HydrophobicContact CD1-CE2 4.41Å; I167-Y171 HydrophobicContact CD1-CG 4.3Å; I167-Y171 PolarHBondContact O-N 3.12Å; I167-Y171 VanDerWaalsContact O-N 3.14Å; I167-I173 HydrophobicContact CG2-CD1 4.33Å; I167-L184 HydrophobicContact CD1-CD2 4.15Å; I167-L184 HydrophobicContact CG1-CD1 4.25Å; I167-L184 HydrophobicContact CG1-CD2 4.32Å; I167-L184 HydrophobicContact CG2-CD1 3.99Å; I167-L184 HydrophobicContact CG2-CD2 3.82Å; I167-M212 HydrophobicContact CD1-CE 4.01Å; I167-M212 HydrophobicContact CG1-CE 3.45Å; I167-M212 VanDerWaalsContact CG1-CE 3.45Å; I167-V216 HydrophobicContact CD1-CG1 3.84Å
168A98.2Very high96.9Very high2 Ų217.9 Ų17.92%0.0179%0.087CC..Hα-helixtrans-62.9-32.9-178.600000112.8V12 V115 V142 S164V12-A168 HydrophobicContact CG1-CB 3.82Å; V12-A168 HydrophobicContact CG2-CB 3.94Å; V115-A168 HydrophobicContact CG2-CB 3.75Å; V142-A168 HydrophobicContact CG2-CB 4.11Å; S164-A168 VanDerWaalsContact O-CB 3.3Å; S164-A168 WeakPolarHBondContact O-CB 3.49Å; S164-A168 PolarHBondContact O-N 2.96Å
169G96.2Very high97.1Very high7 Ų713.9 Ų13.97%0.0727%0.072CC..Hα-helixtrans-90-30.1-175.600000115.2S10 L165 I166 I167S10-G169 WeakPolarHBondContact CB-O 2.93Å; S10-G169 VanDerWaalsContact OG-CA 3.23Å; S10-G169 WeakPolarHBondContact OG-CA 3.35Å; S10-G169 PolarHBondContact OG-O 2.78Å; L165-G169 PolarHBondContact O-N 2.67Å; I166-G169 PolarHBondContact O-N 3.3Å; I167-G169 VanDerWaalsContact C-N 3.26Å; I167-G169 PolarHBondContact O-N 3.2Å
170N94.9Very high97.2Very high6 Ų67.8 Ų7.83%0.0324%0.043CC..Hα-helixtrans-118.4-10.9-169.2-76.1-82.8000114.8E72 R74 V76 I166 R454E72-N170 VanDerWaalsContact OE2-CB 3.3Å; E72-N170 WeakPolarHBondContact OE2-CB 3.5Å; R74-N170 VanDerWaalsContact CB-OD1 3.31Å; R74-N170 WeakPolarHBondContact CB-OD1 3.48Å; R74-N170 PolarHBondContact N-OD1 2.93Å; V76-N170 WeakPolarHBondContact CG2-ND2 3.08Å; I166-N170 WeakPolarHBondContact O-CB 3.37Å; I166-N170 PolarHBondContact O-N 2.95Å; N170-R454 PolarHBondContact O-NH2 2.84Å
171Y94.7Very high97.2Very high35 Ų3510.6 Ų10.614%0.1376%0.058CC..  trans-124.3125.7-173.1-64.9-93.6000112.3E72 I166 I167 I173 V216 V218 W220E72-Y171 PolarHBondContact OE1-OH 3.26Å; E72-Y171 VanDerWaalsContact OE1-OH 3.04Å; E72-Y171 PolarHBondContact OE2-OH 3.03Å; I166-Y171 HydrophobicContact CG2-CD2 4.4Å; I166-Y171 HydrophobicContact CG2-CE2 3.84Å; I167-Y171 HydrophobicContact CD1-CD2 3.97Å; I167-Y171 HydrophobicContact CD1-CE2 4.41Å; I167-Y171 HydrophobicContact CD1-CG 4.3Å; I167-Y171 PolarHBondContact O-N 3.12Å; I167-Y171 VanDerWaalsContact O-N 3.14Å; Y171-I173 VanDerWaalsContact C-N 3.27Å; Y171-I173 PolarHBondContact O-N 3.47Å; Y171-V216 HydrophobicContact CE1-CB 4.35Å; Y171-V216 HydrophobicContact CE1-CG1 4.25Å; Y171-V216 HydrophobicContact CE2-CB 4.26Å; Y171-V216 HydrophobicContact CE2-CG1 4.29Å; Y171-V216 HydrophobicContact CE2-CG2 4.28Å; Y171-V216 WeakPolarHBondContact OH-CB 3.27Å; Y171-V218 HydrophobicContact CD1-CG2 3.67Å; Y171-V218 HydrophobicContact CE1-CG2 3.79Å; Y171-W220 HydrophobicContact CD1-CH2 4.23Å; Y171-W220 HydrophobicContact CD1-CZ2 4.11Å
172D93.3Very high97.1Very high23 Ų2312.9 Ų12.912%0.1237%0.074CC..  trans-80.473175174.765000110.1P174 R225 S479 T482D172-P174 WeakPolarHBondContact O-CD 3.49Å; D172-R225 PolarHBondContact O-NH2 2.93Å; D172-R225 IonicContact OD2-CZ 3.8Å; D172-R225 IonicContact OD2-NH1 3.16Å; D172-R225 PolarHBondContact OD2-NH1 3.29Å; D172-R225 IonicContact OD2-NH2 2.98Å; D172-R225 PolarHBondContact OD2-NH2 3.03Å; D172-R225 VanDerWaalsContact OD2-NH2 3.07Å; D172-S479 VanDerWaalsContact CG-CB 3.46Å; D172-S479 VanDerWaalsContact CG-OG 3.28Å; D172-S479 WeakPolarHBondContact OD1-CB 3.43Å; D172-S479 PolarHBondContact OD1-OG 3.32Å; D172-S479 WeakPolarHBondContact OD2-CB 3.12Å; D172-S479 PolarHBondContact OD2-OG 3Å; D172-T482 PolarHBondContact OD2-OG1 2.85Å
173I95.9Very high97.1Very high0 Ų012.4 Ų12.40%07%0.07CC..  trans-109.194.6176.2-60.5174.4000107.4P140 I167 Y171 E175 T177 L184 L209 V218 W220 V223P140-I173 WeakPolarHBondContact CA-O 3.07Å; P140-I173 VanDerWaalsContact CB-O 3.32Å; P140-I173 WeakPolarHBondContact CB-O 3.31Å; I167-I173 HydrophobicContact CG2-CD1 4.33Å; Y171-I173 VanDerWaalsContact C-N 3.27Å; Y171-I173 PolarHBondContact O-N 3.47Å; I173-E175 HydrophobicContact CG2-CB 4.26Å; I173-E175 HydrophobicContact CG2-CG 4.44Å; I173-E175 PolarHBondContact O-N 2.57Å; I173-T177 HydrophobicContact CG2-CG2 4.25Å; I173-L184 HydrophobicContact CD1-CD2 3.47Å; I173-L184 VanDerWaalsContact CD1-CD2 3.47Å; I173-L209 HydrophobicContact CG2-CD1 4.44Å; I173-V218 HydrophobicContact CD1-CG1 4Å; I173-V218 HydrophobicContact CD1-CG2 4.36Å; I173-W220 HydrophobicContact CG1-CH2 4.25Å; I173-W220 HydrophobicContact CG1-CZ3 4.01Å; I173-V223 HydrophobicContact CG2-CG1 4.22Å
174P96.4Very high97.2Very high13 Ų1312.2 Ų12.28%0.0847%0.069CC..  trans-8053.1-170.835.3-39.2000112.5L137 D172 R225L137-P174 WeakPolarHBondContact O-CB 3.38Å; D172-P174 WeakPolarHBondContact O-CD 3.49Å; P174-R225 HydrophobicContact CG-CB 4.49Å; P174-R225 HydrophobicContact CG-CG 3.83Å
175E98.1Very high97.2Very high9 Ų912.3 Ų12.34%0.0427%0.069CC..SBendtrans-133156.2-176.2-64.3-166.5-12700111.4I141 I173 T177 R186 V223 F224I141-E175 PolarHBondContact N-O 3.38Å; I141-E175 VanDerWaalsContact N-O 3.12Å; I173-E175 HydrophobicContact CG2-CB 4.26Å; I173-E175 HydrophobicContact CG2-CG 4.44Å; I173-E175 PolarHBondContact O-N 2.57Å; E175-T177 HydrophobicContact CB-CG2 3.83Å; E175-R186 IonicContact OE1-CZ 2.93Å; E175-R186 IonicContact OE1-NE 2.93Å; E175-R186 IonicContact OE1-NH2 3.47Å; E175-R186 PolarHBondContact OE1-NH2 3.28Å; E175-R186 IonicContact OE2-CZ 3.61Å; E175-R186 IonicContact OE2-NE 3.36Å; E175-R186 PolarHBondContact OE2-NE 2.99Å; E175-R186 IonicContact OE2-NH2 3.38Å; E175-R186 PolarHBondContact OE2-NH2 2.83Å; E175-R186 VanDerWaalsContact OE2-NH2 3.16Å; E175-V223 WeakPolarHBondContact OE1-CA 3.37Å; E175-F224 HydrophobicContact CG-CB 4.29Å; E175-F224 WeakPolarHBondContact CG-O 3.39Å; E175-F224 PolarHBondContact OE1-N 2.92Å
176V98.8Very high97.2Very high3 Ų313.3 Ų13.32%0.0187%0.073CC..EExtended strand (participates in β ladder)trans-80.8115.5161.7-176.20000108A127 L130 L137 I141 L143 G187A127-V176 HydrophobicContact CB-CG1 4.34Å; A127-V176 WeakPolarHBondContact O-CG1 3.27Å; L130-V176 HydrophobicContact CB-CG1 4.14Å; L130-V176 HydrophobicContact CB-CG2 4.18Å; L137-V176 HydrophobicContact CD2-CG2 4.02Å; I141-V176 HydrophobicContact CB-CG2 4.14Å; I141-V176 HydrophobicContact CD1-CG2 4.19Å; I141-V176 HydrophobicContact CG2-CG1 4.4Å; I141-V176 HydrophobicContact CG2-CG2 4.44Å; I141-V176 CarbonylContact O-C 3.55Å; I141-V176 WeakPolarHBondContact O-CA 3.44Å; L143-V176 HydrophobicContact CD1-CG1 3.29Å; V176-G187 WeakPolarHBondContact O-CA 3.32Å; V176-G187 PolarHBondContact O-N 3.4Å
177T98.9Very high97.3Very high0 Ų012.5 Ų12.50%07%0.069CC..EExtended strand (participates in β ladder)trans-125.7164.8-171.956.20000111.4I141 L143 I173 E175 L184 L185 L209I141-T177 PolarHBondContact O-N 2.91Å; I141-T177 PolarHBondContact O-OG1 3.47Å; L143-T177 WeakPolarHBondContact CD1-O 3.22Å; L143-T177 PolarHBondContact N-O 2.72Å; I173-T177 HydrophobicContact CG2-CG2 4.25Å; E175-T177 HydrophobicContact CB-CG2 3.83Å; T177-L184 HydrophobicContact CG2-CD1 4.34Å; T177-L184 HydrophobicContact CG2-CD2 4.47Å; T177-L184 HydrophobicContact CG2-CG 4.3Å; T177-L184 WeakPolarHBondContact OG1-CD1 3.42Å; T177-L185 CarbonylContact C-O 3.21Å; T177-L185 WeakPolarHBondContact CA-O 3.48Å; T177-L185 VanDerWaalsContact CB-O 3.3Å; T177-L185 WeakPolarHBondContact CB-O 3.21Å; T177-L209 HydrophobicContact CG2-CD1 3.83Å
178I98.8Very high97.3Very high0 Ų012.5 Ų12.50%07%0.069CC..EExtended strand (participates in β ladder)trans-119.3124.3171.1-63.6167.3000108L123 A127 L143 F180 L184 L185 T190L123-I178 HydrophobicContact CD2-CB 4.15Å; L123-I178 HydrophobicContact CD2-CD1 3.25Å; L123-I178 HydrophobicContact CD2-CG1 3.39Å; L123-I178 HydrophobicContact CD2-CG2 3.66Å; A127-I178 HydrophobicContact CB-CD1 3.74Å; A127-I178 HydrophobicContact CB-CG1 3.87Å; L143-I178 HydrophobicContact CB-CG1 4.21Å; L143-I178 WeakPolarHBondContact O-CA 3.44Å; I178-F180 HydrophobicContact CG2-CB 4.32Å; I178-L184 WeakPolarHBondContact O-CA 3.23Å; I178-L185 PolarHBondContact N-O 3.36Å; I178-L185 PolarHBondContact O-N 3.39Å; I178-T190 HydrophobicContact CD1-CG2 3.73Å; I178-T190 WeakPolarHBondContact CD1-OG1 3.35Å
179C98.3Very high97.3Very high1 Ų112.9 Ų12.91%0.0077%0.07CC..EExtended strand (participates in β ladder)trans-104.1113.8172.7174.70000109.4V142 L143 T144 S164 L183 L184 M212V142-C179 HydrophobicContact CG1-CB 3.46Å; V142-C179 VanDerWaalsContact CG1-CB 3.46Å; L143-C179 PolarHBondContact O-N 2.69Å; T144-C179 WeakPolarHBondContact CB-O 3.46Å; T144-C179 PolarHBondContact OG1-O 2.74Å; S164-C179 VanDerWaalsContact OG-CB 3.3Å; S164-C179 WeakPolarHBondContact OG-CB 3.38Å; C179-L183 WeakPolarHBondContact CA-O 3.3Å; C179-L184 HydrophobicContact CB-CD1 4.04Å; C179-M212 HydrophobicContact CB-CE 4.48Å; C179-M212 WeakPolarHBondContact SG-CE 3.12Å
180F97.6Very high97.4Very high5 Ų512.5 Ų12.52%0.0227%0.066CC..EExtended strand (participates in β ladder)trans-152.3136.9-178.7-146.2-91.2000110.5T120 G145 Q147 D156 N160 I178 S182 L183 L198 A200 F201T120-F180 HydrophobicContact CG2-CE2 4.05Å; T120-F180 HydrophobicContact CG2-CZ 4.23Å; G145-F180 WeakPolarHBondContact O-CE2 3.32Å; Q147-F180 HydrophobicContact CG-CE1 4.43Å; Q147-F180 HydrophobicContact CG-CZ 4.13Å; D156-F180 WeakPolarHBondContact OD2-CZ 3.24Å; N160-F180 WeakPolarHBondContact ND2-CD2 3.34Å; N160-F180 VanDerWaalsContact ND2-CE2 3.28Å; N160-F180 WeakPolarHBondContact ND2-CE2 3.01Å; N160-F180 WeakPolarHBondContact ND2-CZ 3.46Å; I178-F180 HydrophobicContact CG2-CB 4.32Å; F180-S182 VanDerWaalsContact C-N 3.31Å; F180-S182 PolarHBondContact O-N 2.97Å; F180-L183 PolarHBondContact N-O 2.7Å; F180-L183 WeakPolarHBondContact O-CB 3.23Å; F180-L183 PolarHBondContact O-N 3.46Å; F180-L198 WeakPolarHBondContact CD1-O 3.39Å; F180-L198 WeakPolarHBondContact CE1-O 3.34Å; F180-A200 HydrophobicContact CD1-CB 4.46Å; F180-A200 HydrophobicContact CE1-CB 3.9Å; F180-A200 HydrophobicContact CZ-CB 4.36Å; F180-F201 HydrophobicContact CB-CD2 3.97Å; F180-F201 AromaticContact CD1-CD2 3.87Å; F180-F201 HydrophobicContact CD1-CD2 3.87Å; F180-F201 HydrophobicContact CD1-CE2 4.29Å; F180-F201 AromaticContact CD2-CD2 3.81Å; F180-F201 HydrophobicContact CD2-CD2 3.81Å; F180-F201 AromaticContact CD2-CE2 3.63Å; F180-F201 HydrophobicContact CD2-CE2 3.63Å; F180-F201 HydrophobicContact CE1-CD2 4.3Å; F180-F201 HydrophobicContact CE1-CE2 4.36Å; F180-F201 HydrophobicContact CE2-CD2 4.24Å; F180-F201 AromaticContact CE2-CE2 3.71Å; F180-F201 HydrophobicContact CE2-CE2 3.71Å; F180-F201 AromaticContact CG-CD2 3.61Å; F180-F201 HydrophobicContact CG-CD2 3.61Å; F180-F201 AromaticContact CG-CE2 3.94Å; F180-F201 HydrophobicContact CG-CE2 3.94Å; F180-F201 HydrophobicContact CZ-CD2 4.48Å; F180-F201 HydrophobicContact CZ-CE2 4.1Å
181N96.3Very high97.5Very high63 Ų6313.4 Ų13.434%0.3377%0.072SC..THydrogen-bonded Turntrans50.648.6175.6-169.739.3000113N160 L183 L198 S199N160-N181 PolarHBondContact OD1-N 2.89Å; N181-L183 PolarHBondContact O-N 2.97Å; N181-L183 VanDerWaalsContact O-N 3.1Å; N181-L198 WeakPolarHBondContact CB-O 3.5Å; N181-S199 WeakPolarHBondContact ND2-CB 3.49Å; N181-S199 PolarHBondContact ND2-OG 3Å
182S96.3Very high97.7Very high49 Ų4914 Ų1434%0.3438%0.076SC..THydrogen-bonded Turntrans61.715.6-179.4-59.80000115.5F180 M212F180-S182 VanDerWaalsContact C-N 3.31Å; F180-S182 PolarHBondContact O-N 2.97Å; S182-M212 PolarHBondContact O-N 3.49Å
183L97.7Very high97.6Very high25 Ų2517.5 Ų17.513%0.1319%0.09CC..EExtended strand (participates in β ladder)trans-112.3142.2173.4-55-178.9000110.6C179 F180 N181 L185 P208 R211C179-L183 WeakPolarHBondContact CA-O 3.3Å; F180-L183 PolarHBondContact N-O 2.7Å; F180-L183 WeakPolarHBondContact O-CB 3.23Å; F180-L183 PolarHBondContact O-N 3.46Å; N181-L183 PolarHBondContact O-N 2.97Å; N181-L183 VanDerWaalsContact O-N 3.1Å; L183-L185 HydrophobicContact CB-CD2 4.09Å; L183-L185 HydrophobicContact CB-CG 4.38Å; L183-L185 HydrophobicContact CD1-CD2 4.45Å; L183-P208 HydrophobicContact CD1-CG 4.41Å; L183-P208 HydrophobicContact CD2-CG 4.42Å; L183-R211 HydrophobicContact CD2-CG 3.81Å; L183-R211 VanDerWaalsContact CD2-NH1 3.26Å
184L98.5Very high97.5Very high0 Ų020.2 Ų20.20%010%0.104CC..EExtended strand (participates in β ladder)trans-106.5115.7164.5-171.171.5000108.8V142 I167 I173 T177 I178 C179 P208 L209 A210V142-L184 HydrophobicContact CG1-CD1 4.28Å; I167-L184 HydrophobicContact CD1-CD2 4.15Å; I167-L184 HydrophobicContact CG1-CD1 4.25Å; I167-L184 HydrophobicContact CG1-CD2 4.32Å; I167-L184 HydrophobicContact CG2-CD1 3.99Å; I167-L184 HydrophobicContact CG2-CD2 3.82Å; I173-L184 HydrophobicContact CD1-CD2 3.47Å; I173-L184 VanDerWaalsContact CD1-CD2 3.47Å; T177-L184 HydrophobicContact CG2-CD1 4.34Å; T177-L184 HydrophobicContact CG2-CD2 4.47Å; T177-L184 HydrophobicContact CG2-CG 4.3Å; T177-L184 WeakPolarHBondContact OG1-CD1 3.42Å; I178-L184 WeakPolarHBondContact O-CA 3.23Å; C179-L184 HydrophobicContact CB-CD1 4.04Å; L184-P208 CarbonylContact O-C 3.59Å; L184-L209 HydrophobicContact CD2-CB 4.33Å; L184-L209 PolarHBondContact O-N 2.89Å; L184-A210 HydrophobicContact CB-CB 3.8Å; L184-A210 HydrophobicContact CD2-CB 4.12Å; L184-A210 PolarHBondContact N-O 3.01Å; L184-A210 PolarHBondContact O-N 2.97Å
185L98.5Very high97.2Very high2 Ų224.7 Ų24.71%0.0114%0.135CC..EExtended strand (participates in β ladder)trans-108.8144.8-177.8-52.5178.6000110.1T177 I178 L183 G187 T190 F201 P208T177-L185 CarbonylContact C-O 3.21Å; T177-L185 WeakPolarHBondContact CA-O 3.48Å; T177-L185 VanDerWaalsContact CB-O 3.3Å; T177-L185 WeakPolarHBondContact CB-O 3.21Å; I178-L185 PolarHBondContact N-O 3.36Å; I178-L185 PolarHBondContact O-N 3.39Å; L183-L185 HydrophobicContact CB-CD2 4.09Å; L183-L185 HydrophobicContact CB-CG 4.38Å; L183-L185 HydrophobicContact CD1-CD2 4.45Å; L185-G187 PolarHBondContact O-N 2.72Å; L185-T190 HydrophobicContact CB-CG2 3.47Å; L185-T190 VanDerWaalsContact CB-CG2 3.47Å; L185-T190 HydrophobicContact CD1-CG2 3.78Å; L185-T190 HydrophobicContact CG-CG2 4.27Å; L185-F201 HydrophobicContact CD1-CB 4.05Å; L185-P208 HydrophobicContact CD2-CB 3.82Å; L185-P208 HydrophobicContact CD2-CG 3.75Å
186R98.6Very high96.8Very high20 Ų2028 Ų288%0.07516%0.164CC..EExtended strand (participates in β ladder)trans-66121.2168.8170.6173.5-69.4141.914.5108.6E175 N188 R189 T190 L209 A222 F224 G381E175-R186 IonicContact OE1-CZ 2.93Å; E175-R186 IonicContact OE1-NE 2.93Å; E175-R186 IonicContact OE1-NH2 3.47Å; E175-R186 PolarHBondContact OE1-NH2 3.28Å; E175-R186 IonicContact OE2-CZ 3.61Å; E175-R186 IonicContact OE2-NE 3.36Å; E175-R186 PolarHBondContact OE2-NE 2.99Å; E175-R186 IonicContact OE2-NH2 3.38Å; E175-R186 PolarHBondContact OE2-NH2 2.83Å; E175-R186 VanDerWaalsContact OE2-NH2 3.16Å; R186-N188 WeakPolarHBondContact CD-OD1 3.04Å; R186-N188 WeakPolarHBondContact CG-OD1 3.37Å; R186-N188 PolarHBondContact O-N 3.01Å; R186-R189 HydrophobicContact CB-CB 4.18Å; R186-R189 HydrophobicContact CB-CG 4.16Å; R186-R189 HydrophobicContact CG-CB 4.27Å; R186-R189 HydrophobicContact CG-CG 3.89Å; R186-R189 WeakPolarHBondContact O-CB 3.41Å; R186-R189 PolarHBondContact O-N 2.83Å; R186-T190 WeakPolarHBondContact O-CG2 3.31Å; R186-L209 HydrophobicContact CB-CD1 4.1Å; R186-L209 HydrophobicContact CB-CG 4.36Å; R186-A222 PolarHBondContact NH2-O 2.66Å; R186-F224 VanDerWaalsContact NH2-CB 3.34Å; R186-F224 VanDerWaalsContact NH2-N 3.18Å; R186-G381 WeakPolarHBondContact CD-O 3.38Å; R186-G381 PolarHBondContact NH1-O 3.01Å
187G98.6Very high96.5Very high0 Ų029 Ų290%017%0.174CC..G310 helixtrans-56.1-47.7-168.700000113.8V176 L185 R189 T190V176-G187 WeakPolarHBondContact O-CA 3.32Å; V176-G187 PolarHBondContact O-N 3.4Å; L185-G187 PolarHBondContact O-N 2.72Å; G187-R189 PolarHBondContact O-N 2.95Å; G187-R189 VanDerWaalsContact O-N 3.12Å; G187-T190 PolarHBondContact O-N 3.32Å; G187-T190 PolarHBondContact O-OG1 2.98Å
188N98.6Very high96.2Very high0 Ų032 Ų320%019%0.19CC..G310 helixtrans-76.211.5178.368.620.7000115S131 R186 A352 R380 E382S131-N188 PolarHBondContact OG-ND2 3.48Å; R186-N188 WeakPolarHBondContact CD-OD1 3.04Å; R186-N188 WeakPolarHBondContact CG-OD1 3.37Å; R186-N188 PolarHBondContact O-N 3.01Å; N188-A352 HydrophobicContact CB-CB 4.34Å; N188-A352 VanDerWaalsContact O-CB 3.23Å; N188-A352 WeakPolarHBondContact O-CB 3.44Å; N188-R380 VanDerWaalsContact ND2-CB 3.32Å; N188-R380 WeakPolarHBondContact ND2-CB 3.35Å; N188-R380 PolarHBondContact ND2-O 2.62Å; N188-E382 HydrophobicContact CB-CB 4.04Å; N188-E382 WeakPolarHBondContact OD1-CA 3.26Å
189R98.4Very high95.9Very high9 Ų934.2 Ų34.23%0.03421%0.205CC..G310 helixtrans-115.91.6171.5-71.7-67-162.7149.64.7112.5R186 G187 S203 P204 V206 D347 G381 E382 T384R186-R189 HydrophobicContact CB-CB 4.18Å; R186-R189 HydrophobicContact CB-CG 4.16Å; R186-R189 HydrophobicContact CG-CB 4.27Å; R186-R189 HydrophobicContact CG-CG 3.89Å; R186-R189 WeakPolarHBondContact O-CB 3.41Å; R186-R189 PolarHBondContact O-N 2.83Å; G187-R189 PolarHBondContact O-N 2.95Å; G187-R189 VanDerWaalsContact O-N 3.12Å; R189-S203 WeakPolarHBondContact O-CA 3.42Å; R189-P204 WeakPolarHBondContact O-CD 3.46Å; R189-V206 HydrophobicContact CG-CB 4.41Å; R189-V206 HydrophobicContact CG-CG2 4.31Å; R189-D347 IonicContact CZ-OD2 3.6Å; R189-D347 IonicContact NH1-OD1 3.84Å; R189-D347 PolarHBondContact NH1-OD1 2.94Å; R189-D347 IonicContact NH1-OD2 2.69Å; R189-D347 PolarHBondContact NH1-OD2 3.06Å; R189-D347 IonicContact NH2-OD2 3.91Å; R189-G381 PolarHBondContact NE-O 3.3Å; R189-G381 PolarHBondContact NH2-O 2.93Å; R189-E382 WeakPolarHBondContact CD-O 3.33Å; R189-E382 PolarHBondContact NE-O 3.42Å; R189-E382 PolarHBondContact NH1-O 3.13Å; R189-T384 PolarHBondContact NH2-OG1 2.8Å
190T98.4Very high95.8Very high0 Ų034.1 Ų34.10%021%0.205CC..  trans-96.7156.3-173.863.10000113.4C124 I178 L185 R186 G187 E202C124-T190 PolarHBondContact SG-OG1 3.38Å; I178-T190 HydrophobicContact CD1-CG2 3.73Å; I178-T190 WeakPolarHBondContact CD1-OG1 3.35Å; L185-T190 HydrophobicContact CB-CG2 3.47Å; L185-T190 VanDerWaalsContact CB-CG2 3.47Å; L185-T190 HydrophobicContact CD1-CG2 3.78Å; L185-T190 HydrophobicContact CG-CG2 4.27Å; R186-T190 WeakPolarHBondContact O-CG2 3.31Å; G187-T190 PolarHBondContact O-N 3.32Å; G187-T190 PolarHBondContact O-OG1 2.98Å; T190-E202 VanDerWaalsContact CA-O 3.26Å; T190-E202 WeakPolarHBondContact CA-O 3.46Å
191T97.9Very high95.8Very high25 Ų2534.2 Ų34.215%0.15321%0.205CC..EExtended strand (participates in β ladder)trans-142.8151.4163.3-171.40000109.6C124 F193 E202 L323 E351C124-T191 VanDerWaalsContact SG-C 3.58Å; C124-T191 VanDerWaalsContact SG-CA 3.58Å; T191-F193 PolarHBondContact O-N 3.28Å; T191-E202 PolarHBondContact N-O 2.69Å; T191-E202 PolarHBondContact O-N 3.35Å; T191-E202 VanDerWaalsContact O-N 3.08Å; T191-L323 HydrophobicContact CG2-CD1 3.36Å; T191-E351 WeakPolarHBondContact CA-OE1 3.41Å; T191-E351 VanDerWaalsContact CB-OE1 3.23Å; T191-E351 WeakPolarHBondContact CB-OE1 3.21Å; T191-E351 PolarHBondContact OG1-OE1 3.18Å
192K97.3Very high95.7Very high48 Ų4834.7 Ų34.721%0.20921%0.205CC..EExtended strand (participates in β ladder)trans-80.3111.5173.1-173.5172.9178178.30108.1T120 D121 D194 A200 F201T120-K192 WeakPolarHBondContact O-CD 3.31Å; T120-K192 PolarHBondContact OG1-NZ 2.93Å; D121-K192 IonicContact OD1-NZ 3.4Å; D121-K192 PolarHBondContact OD1-NZ 2.92Å; K192-D194 WeakPolarHBondContact CE-O 3.3Å; K192-A200 WeakPolarHBondContact CA-O 3.44Å; K192-F201 HydrophobicContact CB-CD1 4.02Å; K192-F201 HydrophobicContact CB-CE1 3.85Å; K192-F201 HydrophobicContact CD-CE1 4.38Å; K192-F201 HydrophobicContact CG-CD1 4.42Å; K192-F201 HydrophobicContact CG-CE1 4.13Å
193F92.2Very high95.8Very high95 Ų9532.6 Ų32.642%0.41719%0.191SC..  trans-103.5-19.2-174.584.9-86.2000113.4T191 S199 A200 F201 E202T191-F193 PolarHBondContact O-N 3.28Å; F193-S199 WeakPolarHBondContact CE1-O 3.3Å; F193-S199 WeakPolarHBondContact CZ-O 3.24Å; F193-A200 WeakPolarHBondContact CD1-O 3.25Å; F193-A200 PolarHBondContact N-O 2.91Å; F193-F201 VanDerWaalsContact CD1-C 3.49Å; F193-E202 HydrophobicContact CB-CB 4.41Å; F193-E202 HydrophobicContact CD1-CB 3.51Å; F193-E202 HydrophobicContact CE1-CB 3.98Å; F193-E202 HydrophobicContact CG-CB 4.12Å
194D92.9Very high95.6Very high57 Ų5732.1 Ų32.131%0.30519%0.189SC..  trans-131.4136.7179.1-164.6-31.1000110.2K192 A196 G197 A200K192-D194 WeakPolarHBondContact CE-O 3.3Å; D194-A196 PolarHBondContact OD1-N 3.49Å; D194-G197 VanDerWaalsContact CG-N 3.32Å; D194-G197 PolarHBondContact OD1-N 3.06Å; D194-A200 PolarHBondContact N-O 2.88Å
195C90.4Very high95.5Very high108 Ų10834.1 Ų34.173%0.7320%0.2SC*.SBendtrans-91.1-21.8179.565.20000113.5Q147Q147-C195 PolarHBondContact NE2-O 3.14Å
196A89.6Confident95.2Very high79 Ų7935.4 Ų35.465%0.65321%0.208SC*.SBendtrans-120.1-31.4-173.100000113.1D194D194-A196 PolarHBondContact OD1-N 3.49Å
197G91.8Very high95Very high22 Ų2238.7 Ų38.723%0.22722%0.224CC..SBendtrans-64.1145.7178.700000112.9Q147 D194 S199Q147-G197 PolarHBondContact NE2-O 3.35Å; D194-G197 VanDerWaalsContact CG-N 3.32Å; D194-G197 PolarHBondContact OD1-N 3.06Å; G197-S199 PolarHBondContact O-N 2.7Å
198L92.7Very high95Very high65 Ų6539.3 Ų39.334%0.3423%0.228SC..SBendtrans-69.6-18170.8-58.9-174.9000112.1Q147 I148 D156 F180 N181 A200Q147-L198 HydrophobicContact CB-CD2 4.18Å; I148-L198 HydrophobicContact CD1-CD2 4.38Å; D156-L198 HydrophobicContact CB-CD2 3.94Å; F180-L198 WeakPolarHBondContact CD1-O 3.39Å; F180-L198 WeakPolarHBondContact CE1-O 3.34Å; N181-L198 WeakPolarHBondContact CB-O 3.5Å; L198-A200 VanDerWaalsContact C-N 3.34Å; L198-A200 PolarHBondContact O-N 2.89Å
199S93.7Very high94.9Very high45 Ų4539.3 Ų39.332%0.31523%0.228SC..  trans-91.370.7165.9-166.30000108.6N181 F193 G197N181-S199 WeakPolarHBondContact ND2-CB 3.49Å; N181-S199 PolarHBondContact ND2-OG 3Å; F193-S199 WeakPolarHBondContact CE1-O 3.3Å; F193-S199 WeakPolarHBondContact CZ-O 3.24Å; G197-S199 PolarHBondContact O-N 2.7Å
200A95.5Very high94.8Very high0 Ų038.9 Ų38.90%023%0.227CC..  trans-78.5-22.6-170.700000114.5Q147 F180 K192 F193 D194 L198Q147-A200 HydrophobicContact CG-CB 4.34Å; F180-A200 HydrophobicContact CD1-CB 4.46Å; F180-A200 HydrophobicContact CE1-CB 3.9Å; F180-A200 HydrophobicContact CZ-CB 4.36Å; K192-A200 WeakPolarHBondContact CA-O 3.44Å; F193-A200 WeakPolarHBondContact CD1-O 3.25Å; F193-A200 PolarHBondContact N-O 2.91Å; D194-A200 PolarHBondContact N-O 2.88Å; L198-A200 VanDerWaalsContact C-N 3.34Å; L198-A200 PolarHBondContact O-N 2.89Å
201F97.4Very high94.8Very high6 Ų645.5 Ų45.53%0.02625%0.252CS..EExtended strand (participates in β ladder)trans-119.5145.8-171.2-60.5-79.6000112.3T120 L123 C124 F180 L185 K192 F193T120-F201 HydrophobicContact CG2-CE2 4.1Å; T120-F201 HydrophobicContact CG2-CZ 4.09Å; L123-F201 HydrophobicContact CB-CE1 4.01Å; L123-F201 HydrophobicContact CB-CZ 3.82Å; L123-F201 HydrophobicContact CD1-CE2 4.26Å; L123-F201 HydrophobicContact CD1-CZ 3.89Å; L123-F201 HydrophobicContact CD2-CE1 4.25Å; L123-F201 HydrophobicContact CD2-CZ 4.13Å; L123-F201 HydrophobicContact CG-CZ 4.18Å; C124-F201 WeakPolarHBondContact SG-CD1 3.3Å; C124-F201 VanDerWaalsContact SG-CE1 3.53Å; F180-F201 HydrophobicContact CB-CD2 3.97Å; F180-F201 AromaticContact CD1-CD2 3.87Å; F180-F201 HydrophobicContact CD1-CD2 3.87Å; F180-F201 HydrophobicContact CD1-CE2 4.29Å; F180-F201 AromaticContact CD2-CD2 3.81Å; F180-F201 HydrophobicContact CD2-CD2 3.81Å; F180-F201 AromaticContact CD2-CE2 3.63Å; F180-F201 HydrophobicContact CD2-CE2 3.63Å; F180-F201 HydrophobicContact CE1-CD2 4.3Å; F180-F201 HydrophobicContact CE1-CE2 4.36Å; F180-F201 HydrophobicContact CE2-CD2 4.24Å; F180-F201 AromaticContact CE2-CE2 3.71Å; F180-F201 HydrophobicContact CE2-CE2 3.71Å; F180-F201 AromaticContact CG-CD2 3.61Å; F180-F201 HydrophobicContact CG-CD2 3.61Å; F180-F201 AromaticContact CG-CE2 3.94Å; F180-F201 HydrophobicContact CG-CE2 3.94Å; F180-F201 HydrophobicContact CZ-CD2 4.48Å; F180-F201 HydrophobicContact CZ-CE2 4.1Å; L185-F201 HydrophobicContact CD1-CB 4.05Å; K192-F201 HydrophobicContact CB-CD1 4.02Å; K192-F201 HydrophobicContact CB-CE1 3.85Å; K192-F201 HydrophobicContact CD-CE1 4.38Å; K192-F201 HydrophobicContact CG-CD1 4.42Å; K192-F201 HydrophobicContact CG-CE1 4.13Å; F193-F201 VanDerWaalsContact CD1-C 3.49Å
202E95.3Very high94.6Very high74 Ų7446 Ų4635%0.34625%0.252SS..EExtended strand (participates in β ladder)trans-134152177-177.358.7-85.800110.2T190 T191 F193T190-E202 VanDerWaalsContact CA-O 3.26Å; T190-E202 WeakPolarHBondContact CA-O 3.46Å; T191-E202 PolarHBondContact N-O 2.69Å; T191-E202 PolarHBondContact O-N 3.35Å; T191-E202 VanDerWaalsContact O-N 3.08Å; F193-E202 HydrophobicContact CB-CB 4.41Å; F193-E202 HydrophobicContact CD1-CB 3.51Å; F193-E202 HydrophobicContact CE1-CB 3.98Å; F193-E202 HydrophobicContact CG-CB 4.12Å
203S97Very high94.3Very high5 Ų546.3 Ų46.34%0.03527%0.269CS..  trans-113.485.9169.4173.20000108.6R189 N205 V206R189-S203 WeakPolarHBondContact O-CA 3.42Å; S203-N205 VanDerWaalsContact C-N 3.31Å; S203-N205 PolarHBondContact O-N 3.18Å; S203-V206 VanDerWaalsContact CB-O 3.3Å; S203-V206 WeakPolarHBondContact CB-O 3.45Å; S203-V206 PolarHBondContact O-N 3.48Å; S203-V206 PolarHBondContact OG-O 3.03Å
204P95.3Very high94.1Very high15 Ų1549.7 Ų49.710%0.09729%0.29CS..THydrogen-bonded Turntrans-68.7-26.6-160.424.9-35.6000114.8R189 L323 R324 T349R189-P204 WeakPolarHBondContact O-CD 3.46Å; P204-L323 HydrophobicContact CB-CD1 4.08Å; P204-L323 HydrophobicContact CB-CG 3.97Å; P204-L323 WeakPolarHBondContact CB-O 3.37Å; P204-L323 HydrophobicContact CG-CD1 4.02Å; P204-L323 HydrophobicContact CG-CG 4.44Å; P204-L323 WeakPolarHBondContact CG-O 3.23Å; P204-R324 HydrophobicContact CB-CB 4.33Å; P204-R324 WeakPolarHBondContact O-CD 3.49Å; P204-R324 WeakPolarHBondContact O-CG 3.34Å; P204-T349 HydrophobicContact CG-CG2 4.46Å
205N94.6Very high93.9Very high41 Ų4153.7 Ų53.722%0.21931%0.307CS..THydrogen-bonded Turntrans-111.3-3.9-173.7-64.5-39.3000113.7S203 G325 D347S203-N205 VanDerWaalsContact C-N 3.31Å; S203-N205 PolarHBondContact O-N 3.18Å; N205-G325 PolarHBondContact ND2-O 2.8Å; N205-G325 PolarHBondContact OD1-N 2.9Å; N205-G325 PolarHBondContact OD1-O 3.46Å; N205-D347 HydrophobicContact CB-CB 4.12Å; N205-D347 PolarHBondContact ND2-O 2.93Å
206V93.7Very high94Very high30 Ų3049.8 Ų49.818%0.18228%0.279CS..SBendtrans-143.9139.5179.2175.40000110.1R189 S203R189-V206 HydrophobicContact CG-CB 4.41Å; R189-V206 HydrophobicContact CG-CG2 4.31Å; S203-V206 VanDerWaalsContact CB-O 3.3Å; S203-V206 WeakPolarHBondContact CB-O 3.45Å; S203-V206 PolarHBondContact O-N 3.48Å; S203-V206 PolarHBondContact OG-O 3.03Å
207Q94.3Very high94.2Very high88 Ų8849.4 Ų49.441%0.41127%0.267SS..  trans-62.2154176.164.7-171.3-1.200113.1K219Q207-K219 VanDerWaalsContact CD-CD 3.49Å; Q207-K219 HydrophobicContact CG-CD 4.13Å; Q207-K219 VanDerWaalsContact NE2-CD 3.26Å
208P97.1Very high94.3Very high13 Ų1348.8 Ų48.88%0.08426%0.258CS..  trans-53.4141.9169.7-26.634.6000112.6L183 L184 L185L183-P208 HydrophobicContact CD1-CG 4.41Å; L183-P208 HydrophobicContact CD2-CG 4.42Å; L184-P208 CarbonylContact O-C 3.59Å; L185-P208 HydrophobicContact CD2-CB 3.82Å; L185-P208 HydrophobicContact CD2-CG 3.75Å
209L97.5Very high94.2Very high0 Ų049.4 Ų49.40%026%0.258CS..SBendtrans-70.4-34.7176.2-64.9179000111.5I173 T177 L184 R186 V218 K219 A222I173-L209 HydrophobicContact CG2-CD1 4.44Å; T177-L209 HydrophobicContact CG2-CD1 3.83Å; L184-L209 HydrophobicContact CD2-CB 4.33Å; L184-L209 PolarHBondContact O-N 2.89Å; R186-L209 HydrophobicContact CB-CD1 4.1Å; R186-L209 HydrophobicContact CB-CG 4.36Å; L209-V218 WeakPolarHBondContact O-CA 3.47Å; L209-K219 PolarHBondContact O-N 3.23Å; L209-A222 HydrophobicContact CD2-CB 4.16Å
210A97.4Very high93.9Very high1 Ų152 Ų521%0.00826%0.261CS..EExtended strand (participates in β ladder)trans-146.4156.5174.200000112.4L184 V216 N217 V218L184-A210 HydrophobicContact CB-CB 3.8Å; L184-A210 HydrophobicContact CD2-CB 4.12Å; L184-A210 PolarHBondContact N-O 3.01Å; L184-A210 PolarHBondContact O-N 2.97Å; A210-V216 HydrophobicContact CB-CG1 4.23Å; A210-N217 WeakPolarHBondContact CA-O 3.43Å; A210-V218 HydrophobicContact CB-CB 4.38Å; A210-V218 HydrophobicContact CB-CG2 3.96Å
211R97Very high93.3Very high139 Ų13957.4 Ų57.453%0.52529%0.29SS..EExtended strand (participates in β ladder)trans-122.7129.9167-64.7-172.4-175.3-95-0.1109.6L183 G213 N217L183-R211 HydrophobicContact CD2-CG 3.81Å; L183-R211 VanDerWaalsContact CD2-NH1 3.26Å; R211-G213 PolarHBondContact O-N 3.44Å; R211-N217 PolarHBondContact N-O 2.84Å; R211-N217 PolarHBondContact O-N 3.47Å
212M93.6Very high93Very high35 Ų3558.3 Ų58.317%0.17230%0.298CS..EExtended strand (participates in β ladder)trans-86.893.3176.2-55.9-179.4-173.900108.6G163 I167 C179 S182 V216G163-M212 WeakPolarHBondContact CA-SD 3.48Å; I167-M212 HydrophobicContact CD1-CE 4.01Å; I167-M212 HydrophobicContact CG1-CE 3.45Å; I167-M212 VanDerWaalsContact CG1-CE 3.45Å; C179-M212 HydrophobicContact CB-CE 4.48Å; C179-M212 WeakPolarHBondContact SG-CE 3.12Å; S182-M212 PolarHBondContact O-N 3.49Å; M212-V216 HydrophobicContact CG-CG2 4.5Å
213G90.7Very high92.8Very high54 Ų5455.5 Ų55.556%0.55729%0.286SS*.SBendtrans-99.2-147.3170.100000110.7R211 Q215R211-G213 PolarHBondContact O-N 3.44Å; G213-Q215 CarbonylContact C-O 3.58Å; G213-Q215 PolarHBondContact N-O 3.43Å; G213-Q215 PolarHBondContact O-N 2.91Å
214I88.4Confident92.6Very high167 Ų16758.1 Ų58.186%0.85630%0.297SS*.SBendtrans-55.6-35166.6-60.5174.2000110.6
215Q89.5Confident92.3Very high141 Ų14159.1 Ų59.166%0.65930%0.299SS*.SBendtrans-121.9151168.6-66.2177.8-28.400108.7G213 N217G213-Q215 CarbonylContact C-O 3.58Å; G213-Q215 PolarHBondContact N-O 3.43Å; G213-Q215 PolarHBondContact O-N 2.91Å; Q215-N217 PolarHBondContact O-N 3.42Å; Q215-N217 PolarHBondContact O-ND2 2.94Å; Q215-N217 VanDerWaalsContact O-ND2 3.1Å
216V93Very high91.7Very high25 Ų2558.9 Ų58.915%0.15230%0.3CS..EExtended strand (participates in β ladder)trans-77.2115.8171.5-176.10000108.8I166 I167 Y171 A210 M212 V218I166-V216 HydrophobicContact CG2-CG2 4.28Å; I167-V216 HydrophobicContact CD1-CG1 3.84Å; Y171-V216 HydrophobicContact CE1-CB 4.35Å; Y171-V216 HydrophobicContact CE1-CG1 4.25Å; Y171-V216 HydrophobicContact CE2-CB 4.26Å; Y171-V216 HydrophobicContact CE2-CG1 4.29Å; Y171-V216 HydrophobicContact CE2-CG2 4.28Å; Y171-V216 WeakPolarHBondContact OH-CB 3.27Å; A210-V216 HydrophobicContact CB-CG1 4.23Å; M212-V216 HydrophobicContact CG-CG2 4.5Å; V216-V218 HydrophobicContact CG1-CG2 4.1Å
217N92.9Very high91.2Very high72 Ų7265.4 Ų65.439%0.38532%0.322SS..EExtended strand (participates in β ladder)trans-100.6101.2-179-72.5-77.5000109.8A210 R211 Q215A210-N217 WeakPolarHBondContact CA-O 3.43Å; R211-N217 PolarHBondContact N-O 2.84Å; R211-N217 PolarHBondContact O-N 3.47Å; Q215-N217 PolarHBondContact O-N 3.42Å; Q215-N217 PolarHBondContact O-ND2 2.94Å; Q215-N217 VanDerWaalsContact O-ND2 3.1Å
218V93.1Very high90.6Very high8 Ų865.7 Ų65.75%0.04833%0.33CS..EExtended strand (participates in β ladder)trans-91.8137.9177.8-172.30000110.6Y171 I173 L209 A210 V216 W220 V223Y171-V218 HydrophobicContact CD1-CG2 3.67Å; Y171-V218 HydrophobicContact CE1-CG2 3.79Å; I173-V218 HydrophobicContact CD1-CG1 4Å; I173-V218 HydrophobicContact CD1-CG2 4.36Å; L209-V218 WeakPolarHBondContact O-CA 3.47Å; A210-V218 HydrophobicContact CB-CB 4.38Å; A210-V218 HydrophobicContact CB-CG2 3.96Å; V216-V218 HydrophobicContact CG1-CG2 4.1Å; V218-W220 HydrophobicContact CB-CD2 4.23Å; V218-W220 HydrophobicContact CB-CZ2 4.04Å; V218-W220 HydrophobicContact CG1-CD2 3.79Å; V218-W220 HydrophobicContact CG1-CE3 3.93Å; V218-W220 HydrophobicContact CG1-CG 4.33Å; V218-W220 HydrophobicContact CG1-CH2 4.2Å; V218-W220 HydrophobicContact CG1-CZ2 4.06Å; V218-W220 HydrophobicContact CG1-CZ3 4.13Å; V218-W220 HydrophobicContact CG2-CZ2 4.18Å; V218-W220 PolarHBondContact O-N 3Å; V218-V223 HydrophobicContact CG1-CG2 4.26Å
219K91.5Very high90Very high79 Ų7971.3 Ų71.334%0.34335%0.349SS..  trans-93.482.3171.6-64.5-169.1175.5179.90110Q207 L209 D221 A222 V223Q207-K219 VanDerWaalsContact CD-CD 3.49Å; Q207-K219 HydrophobicContact CG-CD 4.13Å; Q207-K219 VanDerWaalsContact NE2-CD 3.26Å; L209-K219 PolarHBondContact O-N 3.23Å; K219-D221 PolarHBondContact O-N 2.94Å; K219-A222 HydrophobicContact CB-CB 4.12Å; K219-A222 WeakPolarHBondContact O-CB 3.29Å; K219-A222 PolarHBondContact O-N 3.4Å; K219-V223 PolarHBondContact O-N 3.48Å
220W88.4Confident89.6Confident98 Ų9872.9 Ų72.937%0.37136%0.36SS..THydrogen-bonded Turntrans-61.1-27.9-172.5-68.3113.6000114.5Y171 I173 V218 A222 V223Y171-W220 HydrophobicContact CD1-CH2 4.23Å; Y171-W220 HydrophobicContact CD1-CZ2 4.11Å; I173-W220 HydrophobicContact CG1-CH2 4.25Å; I173-W220 HydrophobicContact CG1-CZ3 4.01Å; V218-W220 HydrophobicContact CB-CD2 4.23Å; V218-W220 HydrophobicContact CB-CZ2 4.04Å; V218-W220 HydrophobicContact CG1-CD2 3.79Å; V218-W220 HydrophobicContact CG1-CE3 3.93Å; V218-W220 HydrophobicContact CG1-CG 4.33Å; V218-W220 HydrophobicContact CG1-CH2 4.2Å; V218-W220 HydrophobicContact CG1-CZ2 4.06Å; V218-W220 HydrophobicContact CG1-CZ3 4.13Å; V218-W220 HydrophobicContact CG2-CZ2 4.18Å; V218-W220 PolarHBondContact O-N 3Å; W220-A222 VanDerWaalsContact C-N 3.26Å; W220-A222 PolarHBondContact O-N 3.3Å; W220-V223 HydrophobicContact CE3-CG2 4.09Å; W220-V223 PolarHBondContact O-N 3.44Å
221D82.8Confident89.4Confident115 Ų11576.8 Ų76.862%0.61538%0.377SS*.THydrogen-bonded Turntrans-67.5-25.1173.661.5-53.6000113.1K219K219-D221 PolarHBondContact O-N 2.94Å
222A89.2Confident89.3Confident24 Ų2471.2 Ų71.220%0.19836%0.358CS..THydrogen-bonded Turntrans-90-16178.900000113.5R186 L209 K219 W220 F224R186-A222 PolarHBondContact NH2-O 2.66Å; L209-A222 HydrophobicContact CD2-CB 4.16Å; K219-A222 HydrophobicContact CB-CB 4.12Å; K219-A222 WeakPolarHBondContact O-CB 3.29Å; K219-A222 PolarHBondContact O-N 3.4Å; W220-A222 VanDerWaalsContact C-N 3.26Å; W220-A222 PolarHBondContact O-N 3.3Å; A222-F224 PolarHBondContact O-N 3.1Å
223V92.7Very high89.4Confident15 Ų1574.2 Ų74.29%0.09137%0.37CS..  trans-67.3123.5-178.7176.60000110.1I173 E175 V218 K219 W220 R225I173-V223 HydrophobicContact CG2-CG1 4.22Å; E175-V223 WeakPolarHBondContact OE1-CA 3.37Å; V218-V223 HydrophobicContact CG1-CG2 4.26Å; K219-V223 PolarHBondContact O-N 3.48Å; W220-V223 HydrophobicContact CE3-CG2 4.09Å; W220-V223 PolarHBondContact O-N 3.44Å; V223-R225 HydrophobicContact CG1-CG 4.2Å
224F91.4Very high89.7Confident60 Ų6072 Ų7226%0.26335%0.346SS..  trans-80.1130.2177.1-173.5-87.7000109.4E175 R186 A222 I379E175-F224 HydrophobicContact CG-CB 4.29Å; E175-F224 WeakPolarHBondContact CG-O 3.39Å; E175-F224 PolarHBondContact OE1-N 2.92Å; R186-F224 VanDerWaalsContact NH2-CB 3.34Å; R186-F224 VanDerWaalsContact NH2-N 3.18Å; A222-F224 PolarHBondContact O-N 3.1Å; F224-I379 WeakPolarHBondContact CZ-O 3.08Å
225R89.5Confident90.1Very high36 Ų3666.9 Ų66.914%0.13632%0.316CS..  trans-132.1137.9179.6-59.4-171173.1-100.70.9109.8D172 P174 V223 G477D172-R225 PolarHBondContact O-NH2 2.93Å; D172-R225 IonicContact OD2-CZ 3.8Å; D172-R225 IonicContact OD2-NH1 3.16Å; D172-R225 PolarHBondContact OD2-NH1 3.29Å; D172-R225 IonicContact OD2-NH2 2.98Å; D172-R225 PolarHBondContact OD2-NH2 3.03Å; D172-R225 VanDerWaalsContact OD2-NH2 3.07Å; P174-R225 HydrophobicContact CG-CB 4.49Å; P174-R225 HydrophobicContact CG-CG 3.83Å; V223-R225 HydrophobicContact CG1-CG 4.2Å; R225-G477 WeakPolarHBondContact CD-O 3.34Å
226S82.9Confident90.4Very high36 Ų3663.8 Ų63.825%0.25230%0.299SS..  trans-66.2142169.2-173.20000109.9D136 V228D136-S226 WeakPolarHBondContact OD1-CB 3.38Å; D136-S226 PolarHBondContact OD1-OG 2.85Å; S226-V228 PolarHBondContact OG-N 2.87Å; S226-V228 VanDerWaalsContact OG-N 3.13Å
227R82.2Confident90.2Very high168 Ų16865.1 Ų65.163%0.63432%0.317SS*.  trans-103.14.7172-63.1-176.1-174.8167.43.5111.9S475R227-S475 WeakPolarHBondContact CB-O 3.29Å
228V82.8Confident90.4Very high94 Ų9462.4 Ų62.457%0.5730%0.303SS*.SBendtrans-84.6135.2179.1-168.10000108.7D136 S226 S230D136-V228 WeakPolarHBondContact OD1-CB 3.46Å; S226-V228 PolarHBondContact OG-N 2.87Å; S226-V228 VanDerWaalsContact OG-N 3.13Å; V228-S230 VanDerWaalsContact C-N 3.3Å; V228-S230 WeakPolarHBondContact CG1-OG 3.29Å; V228-S230 PolarHBondContact O-N 3.47Å; V228-S230 VanDerWaalsContact O-N 3.16Å
229R83.1Confident90.6Very high130 Ų13062.4 Ų62.449%0.49130%0.303SS..  trans-87.968.3179.9-65.4-179.5-70.3178.5-1.8110L474R229-L474 HydrophobicContact CG-CB 4.17Å
230S89.5Confident90.8Very high33 Ų3365.4 Ų65.423%0.23131%0.312CS..SBendtrans-135.5155.2-176.140.40000111.2D136 V228 K508 S509D136-S230 WeakPolarHBondContact CB-OG 3.21Å; D136-S230 PolarHBondContact OD2-OG 3.05Å; V228-S230 VanDerWaalsContact C-N 3.3Å; V228-S230 WeakPolarHBondContact CG1-OG 3.29Å; V228-S230 PolarHBondContact O-N 3.47Å; V228-S230 VanDerWaalsContact O-N 3.16Å; S230-K508 CarbonylContact C-O 3.6Å; S230-S509 CarbonylContact O-C 3.51Å
231K92.8Very high91.1Very high83 Ų8363.3 Ų63.336%0.36131%0.308SS..  trans-64.3153.6160.9-56-163.8172-174.80108.9F233 R507 K508 E543K231-F233 PolarHBondContact O-N 3.45Å; K231-R507 WeakPolarHBondContact CE-O 3.09Å; K231-K508 PolarHBondContact N-O 3.43Å; K231-E543 IonicContact NZ-OE1 2.88Å
232V94.9Very high91.7Very high22 Ų2259.3 Ų59.313%0.13329%0.286CS..  trans-51134.3172.265.80000110Y108 F134 E135 L137Y108-V232 HydrophobicContact CD1-CG1 3.61Å; Y108-V232 HydrophobicContact CD2-CG1 4.27Å; Y108-V232 HydrophobicContact CE1-CB 4.09Å; Y108-V232 HydrophobicContact CE1-CG1 3.58Å; Y108-V232 HydrophobicContact CE2-CG1 4.24Å; Y108-V232 HydrophobicContact CE2-CG2 4.41Å; Y108-V232 HydrophobicContact CG-CG1 3.95Å; F134-V232 HydrophobicContact CD1-CG2 3.81Å; E135-V232 WeakPolarHBondContact O-CA 3.28Å; E135-V232 WeakPolarHBondContact O-CG2 3.35Å; L137-V232 HydrophobicContact CD1-CG2 4.5Å
233F95.3Very high92Very high99 Ų9959 Ų5943%0.43428%0.283SS..EExtended strand (participates in β ladder)trans-123.2133.4176.9179.4-102.3000109.5E135 K231 R235E135-F233 HydrophobicContact CB-CB 4.31Å; E135-F233 HydrophobicContact CG-CD1 4.06Å; E135-F233 PolarHBondContact N-O 2.94Å; E135-F233 PolarHBondContact O-N 3.43Å; E135-F233 WeakPolarHBondContact OE2-CD1 3.48Å; K231-F233 PolarHBondContact O-N 3.45Å; F233-R235 HydrophobicContact CD1-CG 4.02Å; F233-R235 HydrophobicContact CE1-CG 3.52Å
234V97.3Very high92Very high7 Ų761.1 Ų61.14%0.04229%0.294CS..EExtended strand (participates in β ladder)trans-114.1118.6-175-174.90000110.7A101 H105 M133 F134 Y236A101-V234 HydrophobicContact CB-CG1 3.78Å; H105-V234 HydrophobicContact CB-CG2 3.96Å; M133-V234 CarbonylContact O-C 3.34Å; M133-V234 WeakPolarHBondContact O-CA 3.37Å; F134-V234 HydrophobicContact CD1-CG2 3.58Å; F134-V234 HydrophobicContact CE1-CG2 3.41Å; F134-V234 VanDerWaalsContact CE1-CG2 3.41Å; F134-V234 HydrophobicContact CG-CG2 4.37Å; F134-V234 HydrophobicContact CZ-CG1 4.43Å; F134-V234 HydrophobicContact CZ-CG2 4.08Å; V234-Y236 HydrophobicContact CB-CE1 4.26Å; V234-Y236 HydrophobicContact CB-CE2 4.38Å; V234-Y236 HydrophobicContact CG1-CD1 4Å; V234-Y236 HydrophobicContact CG1-CE1 3.51Å; V234-Y236 HydrophobicContact CG1-CE2 4.38Å
235R96.7Very high92.1Very high59 Ų5959.1 Ų59.122%0.22329%0.286CS..  trans-90.9110.9172.6-68-156.8-160.4-92.1-15.7111.1M133 E135 F233 Y359 R363M133-R235 WeakPolarHBondContact CG-O 3.23Å; M133-R235 PolarHBondContact O-N 2.84Å; E135-R235 VanDerWaalsContact CD-NE 3.29Å; E135-R235 HydrophobicContact CG-CG 4.48Å; E135-R235 WeakPolarHBondContact OE1-CD 3.3Å; E135-R235 IonicContact OE1-CZ 3.7Å; E135-R235 IonicContact OE1-NE 2.67Å; E135-R235 PolarHBondContact OE1-NE 2.95Å; E135-R235 IonicContact OE1-NH2 3Å; E135-R235 PolarHBondContact OE1-NH2 3.03Å; E135-R235 IonicContact OE2-CZ 2.69Å; E135-R235 IonicContact OE2-NE 2.68Å; E135-R235 PolarHBondContact OE2-NE 2.88Å; E135-R235 IonicContact OE2-NH2 2.7Å; E135-R235 PolarHBondContact OE2-NH2 3.34Å; F233-R235 HydrophobicContact CD1-CG 4.02Å; F233-R235 HydrophobicContact CE1-CG 3.52Å; R235-Y359 HydrophobicContact CB-CE2 4.45Å; R235-Y359 HydrophobicContact CG-CE2 4.36Å; R235-R363 VanDerWaalsContact NE-CD 3.3Å
236Y95.7Very high92.2Very high76 Ų7663.5 Ų63.530%0.29830%0.303SS..  trans-83.6-27.8176.3-55.6-69.1000113.4T98 A101 K102 H105 V234 L238T98-Y236 HydrophobicContact CG2-CD1 3.85Å; T98-Y236 HydrophobicContact CG2-CG 4.29Å; T98-Y236 PolarHBondContact OG1-O 2.8Å; A101-Y236 HydrophobicContact CB-CD1 4.49Å; A101-Y236 HydrophobicContact CB-CE1 4.26Å; K102-Y236 HydrophobicContact CB-CE1 3.83Å; H105-Y236 PolarHBondContact ND1-OH 3.38Å; V234-Y236 HydrophobicContact CB-CE1 4.26Å; V234-Y236 HydrophobicContact CB-CE2 4.38Å; V234-Y236 HydrophobicContact CG1-CD1 4Å; V234-Y236 HydrophobicContact CG1-CE1 3.51Å; V234-Y236 HydrophobicContact CG1-CE2 4.38Å; Y236-L238 PolarHBondContact O-N 2.68Å
237G90.3Very high92.5Very high53 Ų5361.9 Ų61.955%0.54629%0.291SS..  trans-82.574-17300000113.9G362G237-G362 WeakPolarHBondContact O-CA 3.04Å
238L96.2Very high92.8Very high15 Ų1559.3 Ų59.38%0.07928%0.284CS..  trans-79.9136.1168.8-62.2-178000110.7F94 W97 A129 M133 Y236 R240 A358F94-L238 HydrophobicContact CD1-CB 3.66Å; F94-L238 HydrophobicContact CD1-CD1 3.95Å; F94-L238 HydrophobicContact CD1-CG 4.47Å; F94-L238 HydrophobicContact CE1-CB 3.95Å; F94-L238 HydrophobicContact CE1-CD1 4.34Å; W97-L238 HydrophobicContact CE3-CD1 3.96Å; W97-L238 HydrophobicContact CZ3-CD1 4.47Å; A129-L238 HydrophobicContact CB-CD1 4.41Å; M133-L238 HydrophobicContact CG-CD1 3.93Å; M133-L238 HydrophobicContact CG-CD2 4.05Å; M133-L238 HydrophobicContact CG-CG 4.13Å; M133-L238 HydrophobicContact SD-CD1 3.83Å; M133-L238 HydrophobicContact SD-CG 4.45Å; Y236-L238 PolarHBondContact O-N 2.68Å; L238-R240 PolarHBondContact O-N 3.18Å; L238-A358 HydrophobicContact CB-CB 4.23Å
239D96.7Very high92.7Very high8 Ų859.5 Ų59.54%0.04329%0.288CS..  trans-75125.7174.9-172.510.7000111.5N241 R283 A358 L361D239-N241 WeakPolarHBondContact OD1-CB 3.35Å; D239-N241 PolarHBondContact OD1-N 3.31Å; D239-N241 PolarHBondContact OD1-ND2 3.11Å; D239-R283 IonicContact OD1-CZ 2.67Å; D239-R283 IonicContact OD1-NE 3.76Å; D239-R283 IonicContact OD1-NH2 3.02Å; D239-R283 PolarHBondContact OD1-NH2 3.1Å; D239-R283 IonicContact OD2-CZ 3.71Å; D239-R283 IonicContact OD2-NE 3.95Å; D239-R283 PolarHBondContact OD2-NE 2.92Å; D239-R283 IonicContact OD2-NH2 3.66Å; D239-R283 PolarHBondContact OD2-NH2 3.07Å; D239-A358 WeakPolarHBondContact CB-O 3.4Å; D239-A358 PolarHBondContact N-O 2.82Å; D239-A358 VanDerWaalsContact O-CB 3.3Å; D239-A358 WeakPolarHBondContact O-CB 3.01Å; D239-L361 HydrophobicContact CB-CB 3.6Å; D239-L361 VanDerWaalsContact OD2-CB 3.25Å; D239-L361 WeakPolarHBondContact OD2-CB 3.31Å
240R95.3Very high92.4Very high143 Ų14357.6 Ų57.654%0.5430%0.3SS..  trans-86.6-14.2-178.9-51.9-177.8-174.6176.3-0.6112.8F94 M95 L238 I242F94-R240 HydrophobicContact CB-CG 4.43Å; F94-R240 HydrophobicContact CD1-CG 4.41Å; F94-R240 HydrophobicContact CD2-CB 4.22Å; F94-R240 HydrophobicContact CD2-CG 3.72Å; F94-R240 HydrophobicContact CE2-CB 4.03Å; F94-R240 HydrophobicContact CE2-CG 4.01Å; F94-R240 HydrophobicContact CG-CG 3.94Å; F94-R240 HydrophobicContact CZ-CB 4.46Å; F94-R240 HydrophobicContact CZ-CG 4.46Å; M95-R240 PolarHBondContact SD-NH2 2.63Å; L238-R240 PolarHBondContact O-N 3.18Å; R240-I242 PolarHBondContact O-N 3.36Å
241N96Very high91.5Very high53 Ų5356.9 Ų56.928%0.28329%0.293SS..  trans-83.853.2-174.5-59.5-62.9000112D239 P281 R283 G284D239-N241 WeakPolarHBondContact OD1-CB 3.35Å; D239-N241 PolarHBondContact OD1-N 3.31Å; D239-N241 PolarHBondContact OD1-ND2 3.11Å; N241-P281 WeakPolarHBondContact CB-O 3.45Å; N241-R283 HydrophobicContact CB-CB 4.44Å; N241-R283 HydrophobicContact CB-CG 4.19Å; N241-R283 PolarHBondContact O-N 3.25Å; N241-G284 PolarHBondContact O-N 3.23Å
242I95.6Very high89.9Confident31 Ų3156.3 Ų56.316%0.15930%0.298CS..EExtended strand (participates in β ladder)trans-118.9153.7178.959.8163.5000110.6F94 R240 G284 L354 L357 A358 L361F94-I242 HydrophobicContact CZ-CD1 4.33Å; F94-I242 HydrophobicContact CZ-CG1 4.44Å; R240-I242 PolarHBondContact O-N 3.36Å; I242-G284 VanDerWaalsContact CA-O 3.28Å; I242-G284 WeakPolarHBondContact CA-O 3.43Å; I242-L354 HydrophobicContact CD1-CB 4.18Å; I242-L354 HydrophobicContact CD1-CD2 4.05Å; I242-L354 VanDerWaalsContact CD1-O 3.27Å; I242-L354 WeakPolarHBondContact CD1-O 3.45Å; I242-L357 HydrophobicContact CG2-CD2 4.16Å; I242-L357 HydrophobicContact CG2-CG 3.96Å; I242-A358 HydrophobicContact CD1-CB 3.92Å; I242-L361 HydrophobicContact CG2-CD1 3.68Å
243A94Very high88Confident17 Ų1763.3 Ų63.314%0.1432%0.322CS..EExtended strand (participates in β ladder)trans-137.8155.7174.900000112.2F277 I282 G284 V285 V286A243-F277 HydrophobicContact CB-CD1 4.31Å; A243-I282 HydrophobicContact CB-CD1 4.28Å; A243-I282 HydrophobicContact CB-CG2 4.45Å; A243-G284 PolarHBondContact N-O 3.07Å; A243-V285 HydrophobicContact CB-CG2 4.36Å; A243-V285 CarbonylContact O-C 3.56Å; A243-V285 WeakPolarHBondContact O-CA 3.3Å; A243-V286 PolarHBondContact O-N 3.01Å
244L94.4Very high85.9Confident61 Ų6159.8 Ų59.832%0.31931%0.308SS..EExtended strand (participates in β ladder)trans-109.5124.9169.9-178.965000108.6V286 Q288 V350 L354L244-V286 WeakPolarHBondContact CA-O 3.33Å; L244-V286 HydrophobicContact CD1-CB 3.9Å; L244-V286 HydrophobicContact CD1-CG1 3.77Å; L244-Q288 HydrophobicContact CD1-CG 3.75Å; L244-V350 HydrophobicContact CD1-CG1 3.56Å; L244-V350 HydrophobicContact CD2-CG1 3.66Å; L244-V350 HydrophobicContact CG-CG1 4.27Å; L244-L354 HydrophobicContact CB-CD1 4.11Å; L244-L354 HydrophobicContact CB-CD2 4.1Å; L244-L354 HydrophobicContact CD1-CD1 4.33Å; L244-L354 HydrophobicContact CD2-CD1 4.24Å; L244-L354 HydrophobicContact CG-CD1 4.46Å
245L92.8Very high83.1Confident17 Ų1764.4 Ų64.49%0.08934%0.339CS..EExtended strand (participates in β ladder)trans-119.7111.6175.2-178.960.3000110I247 F274 F277 F278 V285 V286 L287 Q288L245-I247 HydrophobicContact CD2-CD1 4.31Å; L245-I247 HydrophobicContact CG-CD1 4.25Å; L245-F274 HydrophobicContact CD2-CD2 4.04Å; L245-F274 HydrophobicContact CD2-CE2 3.55Å; L245-F274 HydrophobicContact CD2-CZ 4.16Å; L245-F277 HydrophobicContact CD1-CD1 4.33Å; L245-F277 HydrophobicContact CD1-CD2 4.04Å; L245-F277 HydrophobicContact CD1-CE1 4.31Å; L245-F277 HydrophobicContact CD1-CE2 4.04Å; L245-F277 HydrophobicContact CD1-CG 4.2Å; L245-F277 HydrophobicContact CD1-CZ 4.18Å; L245-F277 HydrophobicContact CD2-CB 4.5Å; L245-F278 HydrophobicContact CD2-CE2 3.97Å; L245-F278 HydrophobicContact CD2-CZ 3.95Å; L245-V285 HydrophobicContact CB-CG1 4.1Å; L245-V286 PolarHBondContact N-O 3.44Å; L245-L287 CarbonylContact O-C 3.56Å; L245-L287 WeakPolarHBondContact O-CA 3.28Å; L245-Q288 PolarHBondContact O-N 3.06Å
246R92.5Very high80.4Confident129 Ų12966.9 Ų66.949%0.48736%0.36SS..EExtended strand (participates in β ladder)trans-90.6117.9175.1-171.5176.1-173.7100.7-2.4110.4Q288 Q321R246-Q288 HydrophobicContact CB-CB 4.41Å; R246-Q288 HydrophobicContact CG-CB 4.2Å; R246-Q321 HydrophobicContact CG-CG 4.4Å
247I89.3Confident77.5Confident1 Ų169.3 Ų69.31%0.00538%0.377CS..  trans-73.6141.1177.2-58.1-56.3000110L245 I251 F274 L287 Q288 T289 F290 M295 Q321L245-I247 HydrophobicContact CD2-CD1 4.31Å; L245-I247 HydrophobicContact CG-CD1 4.25Å; I247-I251 HydrophobicContact CB-CD1 4.42Å; I247-I251 HydrophobicContact CD1-CD1 3.79Å; I247-I251 HydrophobicContact CG2-CD1 3.87Å; I247-F274 HydrophobicContact CD1-CE2 4.21Å; I247-L287 HydrophobicContact CD1-CD2 3.66Å; I247-L287 HydrophobicContact CG1-CD2 3.66Å; I247-Q288 WeakPolarHBondContact CB-O 3.44Å; I247-Q288 PolarHBondContact N-O 3.17Å; I247-T289 HydrophobicContact CG1-CG2 4.38Å; I247-F290 HydrophobicContact CB-CZ 4.36Å; I247-F290 HydrophobicContact CG2-CE1 4.3Å; I247-F290 HydrophobicContact CG2-CE2 3.73Å; I247-F290 HydrophobicContact CG2-CZ 3.59Å; I247-F290 WeakPolarHBondContact O-CE1 3.3Å; I247-M295 HydrophobicContact CD1-CE 3.92Å; I247-M295 HydrophobicContact CD1-SD 4.36Å; I247-M295 HydrophobicContact CG1-SD 4.46Å; I247-Q321 PolarHBondContact O-NE2 3.07Å
248F87.2Confident75Confident114 Ų11477.7 Ų77.750%0.539%0.392SS..  trans-137.7154.9174.863.6-81.7000109.8I251F248-I251 HydrophobicContact CD1-CD1 4.4Å; F248-I251 HydrophobicContact CD1-CG1 3.82Å; F248-I251 HydrophobicContact CD2-CG1 4.48Å; F248-I251 HydrophobicContact CE1-CD1 4.44Å; F248-I251 HydrophobicContact CE1-CG1 3.57Å; F248-I251 HydrophobicContact CE2-CG1 4.24Å; F248-I251 HydrophobicContact CG-CG1 4.26Å; F248-I251 HydrophobicContact CZ-CG1 3.79Å; F248-I251 WeakPolarHBondContact O-CG1 3.49Å
249P82Confident72.3Confident99 Ų9982.3 Ų82.364%0.64342%0.421SS*.THydrogen-bonded Turntrans-57.4145.5174.5-24.335.2000110.6I251 F290P249-I251 PolarHBondContact O-N 3.14Å; P249-F290 HydrophobicContact CG-CE1 4.49Å; P249-F290 HydrophobicContact CG-CZ 4.18Å
250A75.6Confident69.7Low90 Ų9087 Ų8774%0.74446%0.462SS*.THydrogen-bonded Turntrans63.631179.100000116.2P252A250-P252 WeakPolarHBondContact O-CD 3.48Å
251I70Confident67.4Low18 Ų1889.7 Ų89.79%0.09248%0.478CS..PPolyproline II helixtrans-47.7120.7157.2-71.3166.2000106.9I247 F248 P249 F274 R299 L302I247-I251 HydrophobicContact CB-CD1 4.42Å; I247-I251 HydrophobicContact CD1-CD1 3.79Å; I247-I251 HydrophobicContact CG2-CD1 3.87Å; F248-I251 HydrophobicContact CD1-CD1 4.4Å; F248-I251 HydrophobicContact CD1-CG1 3.82Å; F248-I251 HydrophobicContact CD2-CG1 4.48Å; F248-I251 HydrophobicContact CE1-CD1 4.44Å; F248-I251 HydrophobicContact CE1-CG1 3.57Å; F248-I251 HydrophobicContact CE2-CG1 4.24Å; F248-I251 HydrophobicContact CG-CG1 4.26Å; F248-I251 HydrophobicContact CZ-CG1 3.79Å; F248-I251 WeakPolarHBondContact O-CG1 3.49Å; P249-I251 PolarHBondContact O-N 3.14Å; I251-F274 HydrophobicContact CG2-CD2 4.48Å; I251-R299 PolarHBondContact O-NH1 2.65Å; I251-L302 HydrophobicContact CB-CD1 4.43Å; I251-L302 HydrophobicContact CG2-CD1 4.07Å; I251-L302 HydrophobicContact CG2-CD2 4.26Å
252P59.5Low64.7Low71 Ų7196 Ų9646%0.46151%0.508SS..PPolyproline II helixtrans-59.1147-166.3-21.729.3000112.1A250 R299A250-P252 WeakPolarHBondContact O-CD 3.48Å; P252-R299 PolarHBondContact O-NH2 2.8Å
253R54.9Low62.2Low168 Ų168104.3 Ų104.363%0.63454%0.543SS*.PPolyproline II helixtrans-90.6120.3173.5-160.2-178.4-154.6-173.27107.3C255R253-C255 PolarHBondContact O-N 2.86Å
254D51.6Low59.9Low26 Ų26112.6 Ų112.614%0.13958%0.576CS.*  trans-75.1113.5158.8-76.19.4000105.8V256 S270 L271D254-V256 PolarHBondContact O-N 3.38Å; D254-S270 WeakPolarHBondContact OD1-CB 3.26Å; D254-S270 PolarHBondContact OD1-OG 2.78Å; D254-L271 HydrophobicContact CB-CB 3.74Å; D254-L271 HydrophobicContact CB-CD2 4.46Å; D254-L271 PolarHBondContact OD1-N 3.29Å; D254-L271 WeakPolarHBondContact OD2-CA 2.79Å; D254-L271 WeakPolarHBondContact OD2-CB 3.46Å; D254-L271 PolarHBondContact OD2-N 3.36Å
255C38.1Very low57.4Low103 Ų103116 Ų11670%0.69659%0.594SS**  trans-59.2107169.4-87.10000108.1R253 I257R253-C255 PolarHBondContact O-N 2.86Å; C255-I257 VanDerWaalsContact C-N 3.3Å; C255-I257 PolarHBondContact O-N 2.84Å
256V40Very low55.1Low111 Ų111122.8 Ų122.867%0.67363%0.629SS**  trans-56.895.3165177.50000107.7D254 R258D254-V256 PolarHBondContact O-N 3.38Å; V256-R258 HydrophobicContact CG1-CG 4.12Å; V256-R258 PolarHBondContact O-N 2.9Å; V256-R258 VanDerWaalsContact O-N 3.16Å
257I34.6Very low52.7Low127 Ų127125.6 Ų125.665%0.65165%0.645SS**  trans-76.398.2164.2-64.6178000106.4C255 T259C255-I257 VanDerWaalsContact C-N 3.3Å; C255-I257 PolarHBondContact O-N 2.84Å; I257-T259 VanDerWaalsContact C-N 3.26Å; I257-T259 WeakPolarHBondContact CG2-OG1 3.13Å; I257-T259 PolarHBondContact O-N 2.86Å
258R38Very low50.9Low229 Ų229131.5 Ų131.586%0.86467%0.673SS**  trans-7183.5160.8-80-177.6170-179.5-2.1108.4V256V256-R258 HydrophobicContact CG1-CG 4.12Å; V256-R258 PolarHBondContact O-N 2.9Å; V256-R258 VanDerWaalsContact O-N 3.16Å
259T40.5Very low49.1Very low112 Ų112133.3 Ų133.369%0.68768%0.683SS**  trans-160.2127.21569.30000109.6I257 F261I257-T259 VanDerWaalsContact C-N 3.26Å; I257-T259 WeakPolarHBondContact CG2-OG1 3.13Å; I257-T259 PolarHBondContact O-N 2.86Å; T259-F261 PolarHBondContact O-N 3.31Å
260A41Very low47.6Very low108 Ų108130.1 Ų130.189%0.89366%0.663SS**THydrogen-bonded Turntrans-75.925.6-160.400000116.2
261F47.1Very low46.8Very low199 Ų199127.7 Ų127.787%0.87364%0.637SS**THydrogen-bonded Turntrans-132.8-0.5-167.2-145-102.8000118T259T259-F261 PolarHBondContact O-N 3.31Å
262M40.2Very low46.4Very low185 Ų185131.1 Ų131.191%0.91166%0.655SS**  trans-13243.4179.8-73-149.285.300115F264M262-F264 PolarHBondContact O-N 2.73Å
263K43.4Very low46.7Very low205 Ų205133.7 Ų133.789%0.89166%0.661SS**  trans-86.74.8-162.8-140.4-179.3-177.4-177.50117.9
264F44.5Very low47.8Very low192 Ų192126.2 Ų126.284%0.84263%0.633SS**SBendtrans-105.9-34.1-159.7-149.9-118.6000119.2M262M262-F264 PolarHBondContact O-N 2.73Å
265L41.8Very low49.2Very low133 Ų133128.6 Ų128.670%0.69664%0.64SS**SBendtrans-144.4125.7-175-93.889000111.9
266L44.7Very low51.1Low159 Ų159126.4 Ų126.483%0.83263%0.63SS**SBendtrans105.8-8.2160.1-60.8154000120.6
267F43.6Very low53Low187 Ų187125.3 Ų125.382%0.8262%0.616SS**  trans-110.915.4-171.8-96.8-87.2000117.7
268Q50.5Low55.5Low125 Ų125119.6 Ų119.658%0.58459%0.587SS**  trans-104.91.4-171.2-80.7-162-40.600116.6S270 L272Q268-S270 PolarHBondContact O-N 3.46Å; Q268-S270 VanDerWaalsContact O-N 3.15Å; Q268-L272 HydrophobicContact CB-CB 4.21Å; Q268-L272 HydrophobicContact CB-CD1 4.41Å; Q268-L272 WeakPolarHBondContact O-CB 3.39Å; Q268-L272 PolarHBondContact O-N 3.3Å
269Q50.2Low57.7Low152 Ų152112.6 Ų112.671%0.7156%0.563SS**Hα-helixtrans-61.5-36.4-157.6-77.8-175.8-8.800116.1Q273Q269-Q273 WeakPolarHBondContact O-CB 3.22Å; Q269-Q273 WeakPolarHBondContact O-CG 3.43Å; Q269-Q273 PolarHBondContact O-N 3.01Å; Q269-Q273 VanDerWaalsContact O-N 3.11Å; Q269-Q273 PolarHBondContact O-NE2 3.01Å
270S50.5Low60Low32 Ų32112.5 Ų112.522%0.22457%0.565CS.*Hα-helixtrans-87.4-43.5-173.1220000115D254 Q268 L272 Q273 F274D254-S270 WeakPolarHBondContact OD1-CB 3.26Å; D254-S270 PolarHBondContact OD1-OG 2.78Å; Q268-S270 PolarHBondContact O-N 3.46Å; Q268-S270 VanDerWaalsContact O-N 3.15Å; S270-L272 VanDerWaalsContact C-N 3.27Å; S270-Q273 WeakPolarHBondContact O-CB 3.15Å; S270-Q273 PolarHBondContact O-N 3.19Å; S270-F274 PolarHBondContact O-N 2.96Å
271L58.7Low62.4Low40 Ų40111.7 Ų111.721%0.20955%0.551CS.*Hα-helixtrans-71.2-29.9173.7-165.272.1000110.2D254 Q273 F274 R275 D301 L302 V305D254-L271 HydrophobicContact CB-CB 3.74Å; D254-L271 HydrophobicContact CB-CD2 4.46Å; D254-L271 PolarHBondContact OD1-N 3.29Å; D254-L271 WeakPolarHBondContact OD2-CA 2.79Å; D254-L271 WeakPolarHBondContact OD2-CB 3.46Å; D254-L271 PolarHBondContact OD2-N 3.36Å; L271-Q273 VanDerWaalsContact C-N 3.32Å; L271-F274 PolarHBondContact O-N 3.3Å; L271-R275 WeakPolarHBondContact O-CB 3.48Å; L271-R275 PolarHBondContact O-N 3.27Å; L271-D301 HydrophobicContact CD1-CB 4.49Å; L271-L302 HydrophobicContact CD1-CD2 4.03Å; L271-V305 HydrophobicContact CD1-CG2 4.39Å
272L60.3Low64.6Low90 Ų90104.2 Ų104.247%0.47152%0.519SS..Hα-helixtrans-65.7-37171.2-155.383.1000111.1Q268 S270 A276Q268-L272 HydrophobicContact CB-CB 4.21Å; Q268-L272 HydrophobicContact CB-CD1 4.41Å; Q268-L272 WeakPolarHBondContact O-CB 3.39Å; Q268-L272 PolarHBondContact O-N 3.3Å; S270-L272 VanDerWaalsContact C-N 3.27Å; L272-A276 WeakPolarHBondContact O-CB 3.22Å; L272-A276 PolarHBondContact O-N 2.9Å
273Q66.1Low67.3Low125 Ų125100.9 Ų100.958%0.58450%0.496SS*.Hα-helixtrans-63.3-48.4171.6-81.9168.159.500111.9Q269 S270 L271 A276 F277Q269-Q273 WeakPolarHBondContact O-CB 3.22Å; Q269-Q273 WeakPolarHBondContact O-CG 3.43Å; Q269-Q273 PolarHBondContact O-N 3.01Å; Q269-Q273 VanDerWaalsContact O-N 3.11Å; Q269-Q273 PolarHBondContact O-NE2 3.01Å; S270-Q273 WeakPolarHBondContact O-CB 3.15Å; S270-Q273 PolarHBondContact O-N 3.19Å; L271-Q273 VanDerWaalsContact C-N 3.32Å; Q273-A276 WeakPolarHBondContact O-CB 3.34Å; Q273-A276 PolarHBondContact O-N 3.31Å; Q273-F277 WeakPolarHBondContact O-CD2 3.13Å
274F77.4Confident69.8Low11 Ų1191.1 Ų91.15%0.04845%0.454CS..Hα-helixtrans-62.3-46.6177.4-174.5-95000111.3L245 I247 I251 S270 L271 A276 F277 F278 M295 L302 V305 I306L245-F274 HydrophobicContact CD2-CD2 4.04Å; L245-F274 HydrophobicContact CD2-CE2 3.55Å; L245-F274 HydrophobicContact CD2-CZ 4.16Å; I247-F274 HydrophobicContact CD1-CE2 4.21Å; I251-F274 HydrophobicContact CG2-CD2 4.48Å; S270-F274 PolarHBondContact O-N 2.96Å; L271-F274 PolarHBondContact O-N 3.3Å; F274-A276 VanDerWaalsContact C-N 3.3Å; F274-A276 PolarHBondContact O-N 2.67Å; F274-F277 PolarHBondContact O-N 3.34Å; F274-F278 HydrophobicContact CD1-CE2 4.06Å; F274-F278 HydrophobicContact CE1-CD2 4.35Å; F274-F278 AromaticContact CE1-CE2 3.6Å; F274-F278 HydrophobicContact CE1-CE2 3.6Å; F274-F278 HydrophobicContact CE1-CZ 4.34Å; F274-F278 HydrophobicContact CE2-CE2 4.36Å; F274-F278 AromaticContact CZ-CE2 3.76Å; F274-F278 HydrophobicContact CZ-CE2 3.76Å; F274-F278 HydrophobicContact CZ-CZ 4.19Å; F274-F278 VanDerWaalsContact O-CD2 3.28Å; F274-F278 WeakPolarHBondContact O-CD2 3.37Å; F274-M295 HydrophobicContact CE2-CE 4.33Å; F274-M295 HydrophobicContact CZ-CE 4.11Å; F274-L302 HydrophobicContact CB-CD2 4.35Å; F274-L302 HydrophobicContact CD1-CD2 3.7Å; F274-L302 HydrophobicContact CD2-CD2 4.03Å; F274-L302 HydrophobicContact CE1-CB 4.11Å; F274-L302 HydrophobicContact CE1-CD2 3.94Å; F274-L302 HydrophobicContact CE2-CD2 4.22Å; F274-L302 HydrophobicContact CG-CD2 3.76Å; F274-L302 HydrophobicContact CZ-CB 4.15Å; F274-L302 HydrophobicContact CZ-CD2 4.19Å; F274-V305 HydrophobicContact CD1-CB 4.14Å; F274-V305 HydrophobicContact CD1-CG1 3.84Å; F274-V305 HydrophobicContact CE1-CB 4.04Å; F274-V305 HydrophobicContact CE1-CG1 3.91Å; F274-I306 HydrophobicContact CE1-CG1 4.19Å; F274-I306 HydrophobicContact CZ-CD1 4.13Å; F274-I306 HydrophobicContact CZ-CG1 4.12Å
275R81.5Confident72.3Confident75 Ų7582 Ų8228%0.28341%0.414SS..Hα-helixtrans-63.9-33178.1-172.4175.2178.796.92.7112.4L271 F277 F278 Q279 V305 E308L271-R275 WeakPolarHBondContact O-CB 3.48Å; L271-R275 PolarHBondContact O-N 3.27Å; R275-F277 VanDerWaalsContact C-N 3.25Å; R275-F277 PolarHBondContact O-N 3.29Å; R275-F278 PolarHBondContact O-N 3.4Å; R275-Q279 WeakPolarHBondContact O-CG 3.43Å; R275-Q279 PolarHBondContact O-N 2.93Å; R275-Q279 PolarHBondContact O-NE2 3.19Å; R275-V305 HydrophobicContact CB-CG1 4.13Å; R275-V305 HydrophobicContact CG-CG1 4.16Å; R275-E308 IonicContact CZ-OE1 2.75Å; R275-E308 IonicContact CZ-OE2 3.4Å; R275-E308 IonicContact NH1-OE1 2.84Å; R275-E308 IonicContact NH1-OE2 3.86Å; R275-E308 PolarHBondContact NH1-OE2 3.45Å; R275-E308 VanDerWaalsContact NH2-CD 3.3Å; R275-E308 IonicContact NH2-OE1 3.77Å; R275-E308 PolarHBondContact NH2-OE1 3.48Å; R275-E308 IonicContact NH2-OE2 3.23Å; R275-E308 PolarHBondContact NH2-OE2 3Å
276A77.7Confident74.9Confident57 Ų5775.6 Ų75.647%0.47138%0.381SS..Hα-helixtrans-59.7-33.1177.900000112.6L272 Q273 F274 F278 Q279L272-A276 WeakPolarHBondContact O-CB 3.22Å; L272-A276 PolarHBondContact O-N 2.9Å; Q273-A276 WeakPolarHBondContact O-CB 3.34Å; Q273-A276 PolarHBondContact O-N 3.31Å; F274-A276 VanDerWaalsContact C-N 3.3Å; F274-A276 PolarHBondContact O-N 2.67Å; A276-F278 PolarHBondContact O-N 2.94Å; A276-F278 VanDerWaalsContact O-N 3.14Å; A276-Q279 PolarHBondContact O-N 2.75Å
277F80.9Confident77.3Confident88 Ų8868.1 Ų68.139%0.38634%0.341SS..THydrogen-bonded Turntrans-62.2-19174-81.6-85.6000113.8A243 L245 Q273 F274 R275 V285A243-F277 HydrophobicContact CB-CD1 4.31Å; L245-F277 HydrophobicContact CD1-CD1 4.33Å; L245-F277 HydrophobicContact CD1-CD2 4.04Å; L245-F277 HydrophobicContact CD1-CE1 4.31Å; L245-F277 HydrophobicContact CD1-CE2 4.04Å; L245-F277 HydrophobicContact CD1-CG 4.2Å; L245-F277 HydrophobicContact CD1-CZ 4.18Å; L245-F277 HydrophobicContact CD2-CB 4.5Å; Q273-F277 WeakPolarHBondContact O-CD2 3.13Å; F274-F277 PolarHBondContact O-N 3.34Å; R275-F277 VanDerWaalsContact C-N 3.25Å; R275-F277 PolarHBondContact O-N 3.29Å; F277-V285 WeakPolarHBondContact O-CG2 3.25Å
278F87.2Confident79.8Confident8 Ų859.9 Ų59.94%0.03531%0.306CS..THydrogen-bonded Turntrans-111.84.9-179-57.3-86.4000113.2L245 F274 R275 A276 V285 L287 V305 I306 A309 L314 V316L245-F278 HydrophobicContact CD2-CE2 3.97Å; L245-F278 HydrophobicContact CD2-CZ 3.95Å; F274-F278 HydrophobicContact CD1-CE2 4.06Å; F274-F278 HydrophobicContact CE1-CD2 4.35Å; F274-F278 AromaticContact CE1-CE2 3.6Å; F274-F278 HydrophobicContact CE1-CE2 3.6Å; F274-F278 HydrophobicContact CE1-CZ 4.34Å; F274-F278 HydrophobicContact CE2-CE2 4.36Å; F274-F278 AromaticContact CZ-CE2 3.76Å; F274-F278 HydrophobicContact CZ-CE2 3.76Å; F274-F278 HydrophobicContact CZ-CZ 4.19Å; F274-F278 VanDerWaalsContact O-CD2 3.28Å; F274-F278 WeakPolarHBondContact O-CD2 3.37Å; R275-F278 PolarHBondContact O-N 3.4Å; A276-F278 PolarHBondContact O-N 2.94Å; A276-F278 VanDerWaalsContact O-N 3.14Å; F278-V285 HydrophobicContact CD1-CB 4.46Å; F278-V285 HydrophobicContact CD1-CG2 3.94Å; F278-V285 HydrophobicContact CE1-CB 4.05Å; F278-V285 HydrophobicContact CE1-CG1 4.02Å; F278-V285 HydrophobicContact CE1-CG2 3.98Å; F278-V285 HydrophobicContact CZ-CG1 4.35Å; F278-L287 HydrophobicContact CE1-CD1 4.13Å; F278-L287 HydrophobicContact CZ-CD1 3.95Å; F278-V305 HydrophobicContact CD2-CG1 3.91Å; F278-V305 HydrophobicContact CE2-CG1 4.43Å; F278-I306 HydrophobicContact CE1-CG1 4.28Å; F278-I306 HydrophobicContact CE2-CG1 4.42Å; F278-I306 HydrophobicContact CZ-CG1 3.88Å; F278-A309 HydrophobicContact CB-CB 3.72Å; F278-A309 HydrophobicContact CD1-CB 3.75Å; F278-A309 HydrophobicContact CG-CB 3.98Å; F278-L314 HydrophobicContact CB-CD1 4.34Å; F278-L314 HydrophobicContact CD1-CD2 4.1Å; F278-V316 HydrophobicContact CD1-CG2 4.47Å; F278-V316 HydrophobicContact CE1-CG2 4.16Å
279Q84.5Confident81.8Confident81 Ų8154 Ų5438%0.37928%0.278SS..SBendtrans-85.3154.9176.9-66.5-48.2-74.500111.7R275 A276 I282R275-Q279 WeakPolarHBondContact O-CG 3.43Å; R275-Q279 PolarHBondContact O-N 2.93Å; R275-Q279 PolarHBondContact O-NE2 3.19Å; A276-Q279 PolarHBondContact O-N 2.75Å; Q279-I282 WeakPolarHBondContact O-CB 3.32Å; Q279-I282 PolarHBondContact O-N 2.81Å; Q279-I282 VanDerWaalsContact O-N 3.1Å
280P87.4Confident83.9Confident111 Ų11149.3 Ų49.372%0.72126%0.255SS*.THydrogen-bonded Turntrans-51.4143.2168.9-26.535.4000112
281P92.3Very high85.9Confident91 Ų9149.5 Ų49.559%0.59126%0.262SS*.THydrogen-bonded Turncis-85.62.811.435-36.8000115.3N241 R283N241-P281 WeakPolarHBondContact CB-O 3.45Å; P281-R283 WeakPolarHBondContact O-CG 3.38Å; P281-R283 PolarHBondContact O-N 2.8Å
282I94.3Very high87.3Confident41 Ų4148.8 Ų48.821%0.2126%0.262CS..  trans-59.2130.9-177.2-56.5-59.5000111.2A243 Q279 G284 V285 L314A243-I282 HydrophobicContact CB-CD1 4.28Å; A243-I282 HydrophobicContact CB-CG2 4.45Å; Q279-I282 WeakPolarHBondContact O-CB 3.32Å; Q279-I282 PolarHBondContact O-N 2.81Å; Q279-I282 VanDerWaalsContact O-N 3.1Å; I282-G284 WeakPolarHBondContact CG2-O 3.35Å; I282-V285 HydrophobicContact CG2-CG2 3.8Å; I282-L314 HydrophobicContact CG2-CD1 4.17Å; I282-L314 WeakPolarHBondContact O-CD1 3.49Å
283R95.6Very high88.8Confident115 Ų11544.5 Ų44.543%0.43424%0.24SC..  trans-115.9-15.2179.7-61.9-161.6-67-177.6-9.5113.5D239 N241 P281 I315 L361D239-R283 IonicContact OD1-CZ 2.67Å; D239-R283 IonicContact OD1-NE 3.76Å; D239-R283 IonicContact OD1-NH2 3.02Å; D239-R283 PolarHBondContact OD1-NH2 3.1Å; D239-R283 IonicContact OD2-CZ 3.71Å; D239-R283 IonicContact OD2-NE 3.95Å; D239-R283 PolarHBondContact OD2-NE 2.92Å; D239-R283 IonicContact OD2-NH2 3.66Å; D239-R283 PolarHBondContact OD2-NH2 3.07Å; N241-R283 HydrophobicContact CB-CB 4.44Å; N241-R283 HydrophobicContact CB-CG 4.19Å; N241-R283 PolarHBondContact O-N 3.25Å; P281-R283 WeakPolarHBondContact O-CG 3.38Å; P281-R283 PolarHBondContact O-N 2.8Å; R283-I315 PolarHBondContact O-N 3.37Å; R283-I315 VanDerWaalsContact O-N 3.1Å; R283-L361 HydrophobicContact CB-CD1 4.06Å; R283-L361 HydrophobicContact CB-CD2 4.27Å
284G96.8Very high90Very high0 Ų039.9 Ų39.90%022%0.219CC..EExtended strand (participates in β ladder)trans-153.8151.2170.600000113.9N241 I242 A243 I282 I315N241-G284 PolarHBondContact O-N 3.23Å; I242-G284 VanDerWaalsContact CA-O 3.28Å; I242-G284 WeakPolarHBondContact CA-O 3.43Å; A243-G284 PolarHBondContact N-O 3.07Å; I282-G284 WeakPolarHBondContact CG2-O 3.35Å; G284-I315 CarbonylContact C-O 3.53Å; G284-I315 WeakPolarHBondContact CA-O 3.31Å
285V96.6Very high90.5Very high0 Ų039.5 Ų39.50%022%0.218CC..EExtended strand (participates in β ladder)trans-131.9129.7-179174.90000109.7A243 L245 F277 F278 I282 L287 L314 I315 V316 V317A243-V285 HydrophobicContact CB-CG2 4.36Å; A243-V285 CarbonylContact O-C 3.56Å; A243-V285 WeakPolarHBondContact O-CA 3.3Å; L245-V285 HydrophobicContact CB-CG1 4.1Å; F277-V285 WeakPolarHBondContact O-CG2 3.25Å; F278-V285 HydrophobicContact CD1-CB 4.46Å; F278-V285 HydrophobicContact CD1-CG2 3.94Å; F278-V285 HydrophobicContact CE1-CB 4.05Å; F278-V285 HydrophobicContact CE1-CG1 4.02Å; F278-V285 HydrophobicContact CE1-CG2 3.98Å; F278-V285 HydrophobicContact CZ-CG1 4.35Å; I282-V285 HydrophobicContact CG2-CG2 3.8Å; V285-L287 HydrophobicContact CG1-CD1 4.22Å; V285-L314 HydrophobicContact CB-CD2 4.24Å; V285-L314 HydrophobicContact CG2-CD2 3.96Å; V285-I315 PolarHBondContact N-O 3.12Å; V285-V316 CarbonylContact O-C 3.59Å; V285-V316 WeakPolarHBondContact O-CA 3.38Å; V285-V317 PolarHBondContact O-N 2.86Å
286V96.7Very high90.6Very high0 Ų037.7 Ų37.70%022%0.215CC..EExtended strand (participates in β ladder)trans-90.4117.9162.91780000107.9A243 L244 L245 V317 C319 A353 L354 L357A243-V286 PolarHBondContact O-N 3.01Å; L244-V286 WeakPolarHBondContact CA-O 3.33Å; L244-V286 HydrophobicContact CD1-CB 3.9Å; L244-V286 HydrophobicContact CD1-CG1 3.77Å; L245-V286 PolarHBondContact N-O 3.44Å; V286-V317 CarbonylContact C-O 3.52Å; V286-V317 WeakPolarHBondContact CA-O 3.3Å; V286-C319 HydrophobicContact CG1-CB 4.18Å; V286-A353 HydrophobicContact CG1-CB 3.98Å; V286-A353 HydrophobicContact CG2-CB 3.93Å; V286-L354 HydrophobicContact CB-CD2 3.98Å; V286-L354 HydrophobicContact CB-CG 4.3Å; V286-L354 HydrophobicContact CG2-CD2 3.71Å; V286-L354 HydrophobicContact CG2-CG 3.95Å; V286-L357 HydrophobicContact CG2-CD2 3.91Å
287L94.9Very high90.9Very high1 Ų136.8 Ų36.81%0.00521%0.206CC..EExtended strand (participates in β ladder)trans-95.8119.7176-111.1125.4000108.9L245 I247 F278 V285 T289 M295 I306 V316 V317 C319L245-L287 CarbonylContact O-C 3.56Å; L245-L287 WeakPolarHBondContact O-CA 3.28Å; I247-L287 HydrophobicContact CD1-CD2 3.66Å; I247-L287 HydrophobicContact CG1-CD2 3.66Å; F278-L287 HydrophobicContact CE1-CD1 4.13Å; F278-L287 HydrophobicContact CZ-CD1 3.95Å; V285-L287 HydrophobicContact CG1-CD1 4.22Å; L287-T289 HydrophobicContact CB-CG2 4.4Å; L287-T289 HydrophobicContact CD2-CG2 4.11Å; L287-M295 HydrophobicContact CD2-SD 4.23Å; L287-I306 HydrophobicContact CD1-CD1 4.15Å; L287-I306 HydrophobicContact CD1-CG1 4.49Å; L287-I306 HydrophobicContact CD2-CD1 4.31Å; L287-V316 HydrophobicContact CB-CG1 4.48Å; L287-V316 HydrophobicContact CD1-CG1 3.23Å; L287-V316 HydrophobicContact CG-CG1 4.45Å; L287-V317 PolarHBondContact N-O 3.21Å; L287-C319 PolarHBondContact O-N 2.86Å
288Q95Very high91Very high15 Ų1538.8 Ų38.87%0.0722%0.216CC..EExtended strand (participates in β ladder)trans-92.2112.8169.2-56.3-167.7-82.300110.5L244 L245 R246 I247 C319 Q321 V350L244-Q288 HydrophobicContact CD1-CG 3.75Å; L245-Q288 PolarHBondContact O-N 3.06Å; R246-Q288 HydrophobicContact CB-CB 4.41Å; R246-Q288 HydrophobicContact CG-CB 4.2Å; I247-Q288 WeakPolarHBondContact CB-O 3.44Å; I247-Q288 PolarHBondContact N-O 3.17Å; Q288-C319 CarbonylContact C-O 3.56Å; Q288-C319 VanDerWaalsContact CA-O 3.28Å; Q288-C319 WeakPolarHBondContact CA-O 3.11Å; Q288-Q321 HydrophobicContact CB-CG 3.68Å; Q288-Q321 PolarHBondContact O-NE2 3.45Å; Q288-V350 HydrophobicContact CG-CG2 4.2Å
289T94.1Very high90.8Very high0 Ų039.4 Ų39.40%022%0.218CC..EExtended strand (participates in β ladder)trans-111.4171.3-17563.10000112.1I247 L287 G293 N294 N318 C319 Q321 L337I247-T289 HydrophobicContact CG1-CG2 4.38Å; L287-T289 HydrophobicContact CB-CG2 4.4Å; L287-T289 HydrophobicContact CD2-CG2 4.11Å; T289-G293 WeakPolarHBondContact OG1-CA 3.09Å; T289-G293 PolarHBondContact OG1-O 3.06Å; T289-N294 WeakPolarHBondContact CB-O 3.49Å; T289-N318 WeakPolarHBondContact CB-OD1 3.28Å; T289-N318 WeakPolarHBondContact CG2-OD1 3.46Å; T289-N318 PolarHBondContact OG1-OD1 2.94Å; T289-C319 PolarHBondContact N-O 3.19Å; T289-C319 PolarHBondContact OG1-O 3.35Å; T289-Q321 WeakPolarHBondContact O-CB 3.49Å; T289-Q321 VanDerWaalsContact O-CG 3.25Å; T289-Q321 WeakPolarHBondContact O-CG 3.37Å; T289-Q321 PolarHBondContact O-N 3.22Å; T289-L337 HydrophobicContact CG2-CD1 3.89Å
290F93.5Very high90.8Very high55 Ų5540.7 Ų40.724%0.24123%0.227CC..BIsolated β-bridgetrans-78142.3-172.9-52.3-54.5000112.3I247 P249 A292 G293 N294 P296I247-F290 HydrophobicContact CB-CZ 4.36Å; I247-F290 HydrophobicContact CG2-CE1 4.3Å; I247-F290 HydrophobicContact CG2-CE2 3.73Å; I247-F290 HydrophobicContact CG2-CZ 3.59Å; I247-F290 WeakPolarHBondContact O-CE1 3.3Å; P249-F290 HydrophobicContact CG-CE1 4.49Å; P249-F290 HydrophobicContact CG-CZ 4.18Å; F290-A292 PolarHBondContact O-N 3.05Å; F290-G293 PolarHBondContact O-N 3.46Å; F290-N294 WeakPolarHBondContact CD2-O 3.18Å; F290-N294 PolarHBondContact N-O 3.19Å; F290-N294 WeakPolarHBondContact O-CB 3.33Å; F290-N294 PolarHBondContact O-N 3.05Å; F290-P296 HydrophobicContact CE2-CG 4.36Å
291G91.9Very high90.6Very high35 Ų3536.5 Ų36.536%0.36120%0.199SC..THydrogen-bonded Turntrans53.1-125.2169.900000112.7G293 S320G291-G293 PolarHBondContact O-N 3.28Å; G291-G293 VanDerWaalsContact O-N 3.08Å; G291-S320 WeakPolarHBondContact O-CB 3.3Å; G291-S320 PolarHBondContact O-OG 3.26Å
292A89.6Confident90.4Very high25 Ų2532.2 Ų32.221%0.20717%0.171CC..THydrogen-bonded Turntrans-76.317.9-179.400000114.7F290 V327 D328 Y331F290-A292 PolarHBondContact O-N 3.05Å; A292-V327 CarbonylContact O-C 3.55Å; A292-V327 VanDerWaalsContact O-CA 3.31Å; A292-V327 WeakPolarHBondContact O-CA 3.49Å; A292-D328 HydrophobicContact CB-CB 4.29Å; A292-D328 PolarHBondContact O-N 3.01Å; A292-Y331 HydrophobicContact CB-CD2 4.18Å; A292-Y331 HydrophobicContact CB-CE2 4.05Å
293G90.3Very high90.1Very high1 Ų131.3 Ų31.31%0.0117%0.167CC..THydrogen-bonded Turntrans114.822.1178.800000115.8T289 F290 G291 N318T289-G293 WeakPolarHBondContact OG1-CA 3.09Å; T289-G293 PolarHBondContact OG1-O 3.06Å; F290-G293 PolarHBondContact O-N 3.46Å; G291-G293 PolarHBondContact O-N 3.28Å; G291-G293 VanDerWaalsContact O-N 3.08Å; G293-N318 PolarHBondContact O-ND2 3.27Å
294N91.1Very high89.8Confident28 Ų2830.8 Ų30.815%0.1517%0.172CC..BIsolated β-bridgetrans-94.9141.1-163.6-63.5-46.3000113.3T289 F290 Y331 T333 G334T289-N294 WeakPolarHBondContact CB-O 3.49Å; F290-N294 WeakPolarHBondContact CD2-O 3.18Å; F290-N294 PolarHBondContact N-O 3.19Å; F290-N294 WeakPolarHBondContact O-CB 3.33Å; F290-N294 PolarHBondContact O-N 3.05Å; N294-Y331 WeakPolarHBondContact OD1-CB 3.38Å; N294-T333 WeakPolarHBondContact CB-OG1 3.41Å; N294-T333 PolarHBondContact OD1-OG1 2.79Å; N294-G334 PolarHBondContact OD1-N 3.01Å
295M88Confident89.5Confident3 Ų331.1 Ų31.12%0.01517%0.174CC..  trans-126.7153.8171.1-169165.7178.800110.1I247 F274 L287 S297 L302 I303 I306 T333 L337I247-M295 HydrophobicContact CD1-CE 3.92Å; I247-M295 HydrophobicContact CD1-SD 4.36Å; I247-M295 HydrophobicContact CG1-SD 4.46Å; F274-M295 HydrophobicContact CE2-CE 4.33Å; F274-M295 HydrophobicContact CZ-CE 4.11Å; L287-M295 HydrophobicContact CD2-SD 4.23Å; M295-S297 PolarHBondContact O-N 3.32Å; M295-L302 HydrophobicContact CE-CB 3.72Å; M295-L302 HydrophobicContact CE-CD1 3.62Å; M295-L302 HydrophobicContact CE-CG 4.31Å; M295-I303 HydrophobicContact SD-CD1 4.14Å; M295-I306 HydrophobicContact CE-CD1 4.28Å; M295-I306 HydrophobicContact SD-CD1 3.92Å; M295-T333 PolarHBondContact N-O 3.28Å; M295-T333 WeakPolarHBondContact O-CB 2.85Å; M295-L337 HydrophobicContact CB-CD1 4.11Å; M295-L337 HydrophobicContact CB-CD2 4.39Å; M295-L337 HydrophobicContact CB-CG 4.38Å; M295-L337 HydrophobicContact SD-CD2 3.97Å
296P85.3Confident89.2Confident36 Ų3631.1 Ų31.123%0.23417%0.174CC..  trans-59.1111.9180-25.836.2000112.2F290 H298 R299F290-P296 HydrophobicContact CE2-CG 4.36Å; P296-H298 VanDerWaalsContact C-N 3.27Å; P296-H298 PolarHBondContact O-N 3.05Å; P296-R299 HydrophobicContact CB-CB 4.44Å; P296-R299 HydrophobicContact CB-CG 3.95Å; P296-R299 WeakPolarHBondContact O-CB 3.36Å; P296-R299 PolarHBondContact O-N 3.37Å
297S82.9Confident89.1Confident39 Ų3934.2 Ų34.227%0.27319%0.189SC..THydrogen-bonded Turntrans-68.6-20.7-175.9520000114.5M295 R299M295-S297 PolarHBondContact O-N 3.32Å; S297-R299 PolarHBondContact O-N 2.92Å
298H83.8Confident89Confident130 Ų13037.1 Ų37.160%0.60220%0.202SC*.THydrogen-bonded Turntrans-82.47.4176.862.3-90.6000113.7P296P296-H298 VanDerWaalsContact C-N 3.27Å; P296-H298 PolarHBondContact O-N 3.05Å
299R83.4Confident88.9Confident21 Ų2136.7 Ų36.78%0.07920%0.201CC..  trans-107.759.4-179.8-68.1-62.1-58.7-851.3111.1I251 P252 P296 S297 D301 L302 I303I251-R299 PolarHBondContact O-NH1 2.65Å; P252-R299 PolarHBondContact O-NH2 2.8Å; P296-R299 HydrophobicContact CB-CB 4.44Å; P296-R299 HydrophobicContact CB-CG 3.95Å; P296-R299 WeakPolarHBondContact O-CB 3.36Å; P296-R299 PolarHBondContact O-N 3.37Å; S297-R299 PolarHBondContact O-N 2.92Å; R299-D301 WeakPolarHBondContact CA-OD1 3.35Å; R299-D301 IonicContact CZ-OD1 3.54Å; R299-D301 IonicContact CZ-OD2 3.87Å; R299-D301 IonicContact NE-OD1 2.8Å; R299-D301 PolarHBondContact NE-OD1 3.45Å; R299-D301 IonicContact NE-OD2 2.87Å; R299-D301 PolarHBondContact NE-OD2 2.91Å; R299-D301 IonicContact NH2-OD1 3.43Å; R299-D301 IonicContact NH2-OD2 3.13Å; R299-D301 PolarHBondContact NH2-OD2 3.26Å; R299-D301 PolarHBondContact O-N 3.47Å; R299-D301 VanDerWaalsContact O-N 3.13Å; R299-L302 HydrophobicContact CB-CB 4.3Å; R299-L302 HydrophobicContact CB-CD1 3.98Å; R299-L302 HydrophobicContact CB-CG 4.08Å; R299-L302 HydrophobicContact CG-CD1 4.31Å; R299-L302 PolarHBondContact O-N 3.24Å; R299-I303 PolarHBondContact O-N 3.36Å; R299-I303 VanDerWaalsContact O-N 3.16Å
300D84.5Confident89Confident107 Ų10737.2 Ų37.257%0.57221%0.205SC*.Hα-helixtrans-51.9-34.9176.1-56.4-24.3000111.4L302 I303 D304D300-L302 VanDerWaalsContact C-N 3.28Å; D300-L302 PolarHBondContact O-N 2.82Å; D300-I303 PolarHBondContact O-N 3.41Å; D300-D304 VanDerWaalsContact O-CB 3.25Å; D300-D304 WeakPolarHBondContact O-CB 3.29Å; D300-D304 PolarHBondContact O-N 3Å
301D82.4Confident89.1Confident23 Ų2342.3 Ų42.312%0.12322%0.222CC..Hα-helixtrans-57.3-36.4175.560.5-57.5000113.7L271 R299 V305L271-D301 HydrophobicContact CD1-CB 4.49Å; R299-D301 WeakPolarHBondContact CA-OD1 3.35Å; R299-D301 IonicContact CZ-OD1 3.54Å; R299-D301 IonicContact CZ-OD2 3.87Å; R299-D301 IonicContact NE-OD1 2.8Å; R299-D301 PolarHBondContact NE-OD1 3.45Å; R299-D301 IonicContact NE-OD2 2.87Å; R299-D301 PolarHBondContact NE-OD2 2.91Å; R299-D301 IonicContact NH2-OD1 3.43Å; R299-D301 IonicContact NH2-OD2 3.13Å; R299-D301 PolarHBondContact NH2-OD2 3.26Å; R299-D301 PolarHBondContact O-N 3.47Å; R299-D301 VanDerWaalsContact O-N 3.13Å; D301-V305 WeakPolarHBondContact O-CG2 3.28Å
302L87.5Confident89.1Confident2 Ų246.3 Ų46.31%0.0124%0.235CC..Hα-helixtrans-81.8-40.4177.1-59.3-178.3000111.5I251 L271 F274 M295 R299 D300 D304 V305 I306I251-L302 HydrophobicContact CB-CD1 4.43Å; I251-L302 HydrophobicContact CG2-CD1 4.07Å; I251-L302 HydrophobicContact CG2-CD2 4.26Å; L271-L302 HydrophobicContact CD1-CD2 4.03Å; F274-L302 HydrophobicContact CB-CD2 4.35Å; F274-L302 HydrophobicContact CD1-CD2 3.7Å; F274-L302 HydrophobicContact CD2-CD2 4.03Å; F274-L302 HydrophobicContact CE1-CB 4.11Å; F274-L302 HydrophobicContact CE1-CD2 3.94Å; F274-L302 HydrophobicContact CE2-CD2 4.22Å; F274-L302 HydrophobicContact CG-CD2 3.76Å; F274-L302 HydrophobicContact CZ-CB 4.15Å; F274-L302 HydrophobicContact CZ-CD2 4.19Å; M295-L302 HydrophobicContact CE-CB 3.72Å; M295-L302 HydrophobicContact CE-CD1 3.62Å; M295-L302 HydrophobicContact CE-CG 4.31Å; R299-L302 HydrophobicContact CB-CB 4.3Å; R299-L302 HydrophobicContact CB-CD1 3.98Å; R299-L302 HydrophobicContact CB-CG 4.08Å; R299-L302 HydrophobicContact CG-CD1 4.31Å; R299-L302 PolarHBondContact O-N 3.24Å; D300-L302 VanDerWaalsContact C-N 3.28Å; D300-L302 PolarHBondContact O-N 2.82Å; L302-D304 VanDerWaalsContact C-N 3.33Å; L302-V305 PolarHBondContact O-N 3.46Å; L302-I306 WeakPolarHBondContact O-CG1 3.36Å; L302-I306 PolarHBondContact O-N 3.45Å; L302-I306 VanDerWaalsContact O-N 3.15Å
303I88.8Confident89.4Confident22 Ų2246.4 Ų46.411%0.11324%0.239CC..Hα-helixtrans-64.5-39.8178.9-58.7-58.7000110.5M295 R299 D300 V305 I306 H307 I336 L337 A340M295-I303 HydrophobicContact SD-CD1 4.14Å; R299-I303 PolarHBondContact O-N 3.36Å; R299-I303 VanDerWaalsContact O-N 3.16Å; D300-I303 PolarHBondContact O-N 3.41Å; I303-V305 VanDerWaalsContact C-N 3.35Å; I303-V305 PolarHBondContact O-N 2.91Å; I303-I306 PolarHBondContact O-N 3.21Å; I303-H307 VanDerWaalsContact O-CB 3.3Å; I303-H307 WeakPolarHBondContact O-CB 3.46Å; I303-H307 PolarHBondContact O-N 2.74Å; I303-I336 HydrophobicContact CD1-CD1 3.82Å; I303-I336 HydrophobicContact CD1-CG1 4.14Å; I303-I336 HydrophobicContact CG1-CD1 4.25Å; I303-L337 HydrophobicContact CD1-CD2 3.92Å; I303-A340 HydrophobicContact CG2-CB 4.07Å
304D89.2Confident89.7Confident103 Ų10347 Ų4755%0.55124%0.242SC*.Hα-helixtrans-61-41.5176.1-77.9-19.7000112D300 L302 H307 E308D300-D304 VanDerWaalsContact O-CB 3.25Å; D300-D304 WeakPolarHBondContact O-CB 3.29Å; D300-D304 PolarHBondContact O-N 3Å; L302-D304 VanDerWaalsContact C-N 3.33Å; D304-H307 PolarHBondContact O-N 2.98Å; D304-E308 VanDerWaalsContact O-CB 3.29Å; D304-E308 WeakPolarHBondContact O-CB 3.35Å; D304-E308 PolarHBondContact O-N 3.24Å
305V89.5Confident90Very high8 Ų845.7 Ų45.75%0.04824%0.235CC..Hα-helixtrans-63.6-43.7175.9170.70000111.1L271 F274 R275 F278 D301 L302 I303 A309L271-V305 HydrophobicContact CD1-CG2 4.39Å; F274-V305 HydrophobicContact CD1-CB 4.14Å; F274-V305 HydrophobicContact CD1-CG1 3.84Å; F274-V305 HydrophobicContact CE1-CB 4.04Å; F274-V305 HydrophobicContact CE1-CG1 3.91Å; R275-V305 HydrophobicContact CB-CG1 4.13Å; R275-V305 HydrophobicContact CG-CG1 4.16Å; F278-V305 HydrophobicContact CD2-CG1 3.91Å; F278-V305 HydrophobicContact CE2-CG1 4.43Å; D301-V305 WeakPolarHBondContact O-CG2 3.28Å; L302-V305 PolarHBondContact O-N 3.46Å; I303-V305 VanDerWaalsContact C-N 3.35Å; I303-V305 PolarHBondContact O-N 2.91Å; V305-A309 WeakPolarHBondContact O-CB 3.36Å; V305-A309 PolarHBondContact O-N 3.47Å
306I92Very high90.4Very high0 Ų045.6 Ų45.60%023%0.234CC..Hα-helixtrans-64.2-46176.8-65.9169.4000110.2F274 F278 L287 M295 L302 I303 E308 A309 V310 V316 L337 A340 V342F274-I306 HydrophobicContact CE1-CG1 4.19Å; F274-I306 HydrophobicContact CZ-CD1 4.13Å; F274-I306 HydrophobicContact CZ-CG1 4.12Å; F278-I306 HydrophobicContact CE1-CG1 4.28Å; F278-I306 HydrophobicContact CE2-CG1 4.42Å; F278-I306 HydrophobicContact CZ-CG1 3.88Å; L287-I306 HydrophobicContact CD1-CD1 4.15Å; L287-I306 HydrophobicContact CD1-CG1 4.49Å; L287-I306 HydrophobicContact CD2-CD1 4.31Å; M295-I306 HydrophobicContact CE-CD1 4.28Å; M295-I306 HydrophobicContact SD-CD1 3.92Å; L302-I306 WeakPolarHBondContact O-CG1 3.36Å; L302-I306 PolarHBondContact O-N 3.45Å; L302-I306 VanDerWaalsContact O-N 3.15Å; I303-I306 PolarHBondContact O-N 3.21Å; I306-E308 VanDerWaalsContact C-N 3.35Å; I306-E308 PolarHBondContact O-N 3.27Å; I306-A309 WeakPolarHBondContact O-CB 3.31Å; I306-A309 PolarHBondContact O-N 2.98Å; I306-V310 HydrophobicContact CG2-CG2 4.41Å; I306-V310 WeakPolarHBondContact O-CG2 3.37Å; I306-V310 PolarHBondContact O-N 3.27Å; I306-V316 HydrophobicContact CG2-CG1 4.5Å; I306-L337 HydrophobicContact CD1-CD2 3.95Å; I306-A340 HydrophobicContact CG2-CB 4.5Å; I306-V342 HydrophobicContact CG2-CG2 3.38Å
307H93.8Very high90.9Very high65 Ų6543.9 Ų43.930%0.30122%0.223SC..Hα-helixtrans-63.3-41.5-178.9-176.251.5000111.6I303 D304 V310 R311 A340I303-H307 VanDerWaalsContact O-CB 3.3Å; I303-H307 WeakPolarHBondContact O-CB 3.46Å; I303-H307 PolarHBondContact O-N 2.74Å; D304-H307 PolarHBondContact O-N 2.98Å; H307-V310 PolarHBondContact O-N 2.83Å; H307-R311 PolarHBondContact CD2-NH2 3.48Å; H307-R311 PolarHBondContact NE2-NH2 3.32Å; H307-R311 WeakPolarHBondContact O-CB 3.43Å; H307-R311 PolarHBondContact O-N 3.08Å; H307-A340 HydrophobicContact CB-CB 3.92Å; H307-A340 PolarHBondContact ND1-O 3.16Å
308E92.8Very high91.5Very high61 Ų6142.2 Ų42.229%0.28521%0.211SC..Hα-helixtrans-62-45172.8-171.4-174.1161.600111.7R275 D304 I306 V310 R311 N312R275-E308 IonicContact CZ-OE1 2.75Å; R275-E308 IonicContact CZ-OE2 3.4Å; R275-E308 IonicContact NH1-OE1 2.84Å; R275-E308 IonicContact NH1-OE2 3.86Å; R275-E308 PolarHBondContact NH1-OE2 3.45Å; R275-E308 VanDerWaalsContact NH2-CD 3.3Å; R275-E308 IonicContact NH2-OE1 3.77Å; R275-E308 PolarHBondContact NH2-OE1 3.48Å; R275-E308 IonicContact NH2-OE2 3.23Å; R275-E308 PolarHBondContact NH2-OE2 3Å; D304-E308 VanDerWaalsContact O-CB 3.29Å; D304-E308 WeakPolarHBondContact O-CB 3.35Å; D304-E308 PolarHBondContact O-N 3.24Å; I306-E308 VanDerWaalsContact C-N 3.35Å; I306-E308 PolarHBondContact O-N 3.27Å; E308-V310 PolarHBondContact O-N 3.24Å; E308-R311 WeakPolarHBondContact O-CB 3.46Å; E308-R311 PolarHBondContact O-N 3.29Å; E308-N312 WeakPolarHBondContact O-CB 3.35Å; E308-N312 VanDerWaalsContact O-CG 3.25Å; E308-N312 PolarHBondContact O-N 2.93Å; E308-N312 PolarHBondContact O-ND2 3.1Å
309A92.9Very high92Very high6 Ų636.1 Ų36.15%0.0518%0.183CC..Hα-helixtrans-59.9-46.9177.400000111.9F278 V305 I306 R311 N312 G313 L314F278-A309 HydrophobicContact CB-CB 3.72Å; F278-A309 HydrophobicContact CD1-CB 3.75Å; F278-A309 HydrophobicContact CG-CB 3.98Å; V305-A309 WeakPolarHBondContact O-CB 3.36Å; V305-A309 PolarHBondContact O-N 3.47Å; I306-A309 WeakPolarHBondContact O-CB 3.31Å; I306-A309 PolarHBondContact O-N 2.98Å; A309-R311 VanDerWaalsContact C-N 3.33Å; A309-R311 PolarHBondContact O-N 2.86Å; A309-N312 CarbonylContact O-C 3.57Å; A309-N312 PolarHBondContact O-N 2.95Å; A309-G313 PolarHBondContact O-N 2.82Å; A309-L314 HydrophobicContact CB-CB 4.28Å; A309-L314 HydrophobicContact CB-CD1 4.47Å; A309-L314 WeakPolarHBondContact O-CB 3.4Å; A309-L314 PolarHBondContact O-N 2.79Å; A309-L314 VanDerWaalsContact O-N 3.09Å
310V95.6Very high92.5Very high12 Ų1235.9 Ų35.97%0.07319%0.185CC..Hα-helixtrans-62.5-40.8177.4171.80000111.4I306 H307 E308 N312 G313 L314 V316 G341I306-V310 HydrophobicContact CG2-CG2 4.41Å; I306-V310 WeakPolarHBondContact O-CG2 3.37Å; I306-V310 PolarHBondContact O-N 3.27Å; H307-V310 PolarHBondContact O-N 2.83Å; E308-V310 PolarHBondContact O-N 3.24Å; V310-N312 VanDerWaalsContact C-N 3.26Å; V310-N312 PolarHBondContact O-N 2.81Å; V310-G313 PolarHBondContact O-N 2.83Å; V310-L314 WeakPolarHBondContact CA-O 3.49Å; V310-V316 HydrophobicContact CG2-CB 4.06Å; V310-V316 HydrophobicContact CG2-CG2 3.62Å; V310-G341 WeakPolarHBondContact CG1-O 3.08Å
311R95Very high93.1Very high161 Ų16133 Ų3361%0.60817%0.168SC*.Hα-helixtrans-62.3-35.3176.2-166.5-170.3-52.4142.82.7112H307 E308 A309 G313H307-R311 PolarHBondContact CD2-NH2 3.48Å; H307-R311 PolarHBondContact NE2-NH2 3.32Å; H307-R311 WeakPolarHBondContact O-CB 3.43Å; H307-R311 PolarHBondContact O-N 3.08Å; E308-R311 WeakPolarHBondContact O-CB 3.46Å; E308-R311 PolarHBondContact O-N 3.29Å; A309-R311 VanDerWaalsContact C-N 3.33Å; A309-R311 PolarHBondContact O-N 2.86Å; R311-G313 PolarHBondContact O-N 3.3Å
312N93.5Very high93.7Very high119 Ų11935 Ų3564%0.63618%0.183SC*.THydrogen-bonded Turntrans-78.78.8175.9-66.3-19.9000113.5E308 A309 V310E308-N312 WeakPolarHBondContact O-CB 3.35Å; E308-N312 VanDerWaalsContact O-CG 3.25Å; E308-N312 PolarHBondContact O-N 2.93Å; E308-N312 PolarHBondContact O-ND2 3.1Å; A309-N312 CarbonylContact O-C 3.57Å; A309-N312 PolarHBondContact O-N 2.95Å; V310-N312 VanDerWaalsContact C-N 3.26Å; V310-N312 PolarHBondContact O-N 2.81Å
313G95Very high93.9Very high28 Ų2839.4 Ų39.429%0.28921%0.206SC..THydrogen-bonded Turntrans92.83.9172.800000115.2A309 V310 R311 L368A309-G313 PolarHBondContact O-N 2.82Å; V310-G313 PolarHBondContact O-N 2.83Å; R311-G313 PolarHBondContact O-N 3.3Å; G313-L368 WeakPolarHBondContact O-CD1 3.37Å
314L95.9Very high94.1Very high12 Ų1247.9 Ų47.96%0.06324%0.237CC..  trans-71.9133.3175.7-164146.2000110F278 I282 V285 A309 V310 V316F278-L314 HydrophobicContact CB-CD1 4.34Å; F278-L314 HydrophobicContact CD1-CD2 4.1Å; I282-L314 HydrophobicContact CG2-CD1 4.17Å; I282-L314 WeakPolarHBondContact O-CD1 3.49Å; V285-L314 HydrophobicContact CB-CD2 4.24Å; V285-L314 HydrophobicContact CG2-CD2 3.96Å; A309-L314 HydrophobicContact CB-CB 4.28Å; A309-L314 HydrophobicContact CB-CD1 4.47Å; A309-L314 WeakPolarHBondContact O-CB 3.4Å; A309-L314 PolarHBondContact O-N 2.79Å; A309-L314 VanDerWaalsContact O-N 3.09Å; V310-L314 WeakPolarHBondContact CA-O 3.49Å; L314-V316 HydrophobicContact CD2-CG2 3.38Å
315I97.4Very high94Very high1 Ų144.7 Ų44.71%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-89.8115.2176.6-61.2-178.1000109R283 G284 V285 V317 L343 L357 L361 L368 K371 K372 M375R283-I315 PolarHBondContact O-N 3.37Å; R283-I315 VanDerWaalsContact O-N 3.1Å; G284-I315 CarbonylContact C-O 3.53Å; G284-I315 WeakPolarHBondContact CA-O 3.31Å; V285-I315 PolarHBondContact N-O 3.12Å; I315-V317 HydrophobicContact CG2-CG2 4.15Å; I315-L343 HydrophobicContact CG2-CD1 3.76Å; I315-L357 HydrophobicContact CB-CD1 4.03Å; I315-L357 HydrophobicContact CG2-CD1 3.76Å; I315-L361 HydrophobicContact CD1-CD2 3.83Å; I315-L361 HydrophobicContact CG1-CD2 4.25Å; I315-L368 HydrophobicContact CD1-CD1 3.99Å; I315-L368 HydrophobicContact CG1-CD1 3.8Å; I315-K371 HydrophobicContact CD1-CB 3.69Å; I315-K372 HydrophobicContact CD1-CG 4.42Å; I315-K372 HydrophobicContact CG1-CG 4.4Å; I315-M375 HydrophobicContact CG2-CG 4.28Å
316V96.8Very high93.9Very high1 Ų150.6 Ų50.61%0.00625%0.25CS..EExtended strand (participates in β ladder)trans-107.9131.6176.5-171.60000109.3F278 V285 L287 I306 V310 L314 V342 L343F278-V316 HydrophobicContact CD1-CG2 4.47Å; F278-V316 HydrophobicContact CE1-CG2 4.16Å; V285-V316 CarbonylContact O-C 3.59Å; V285-V316 WeakPolarHBondContact O-CA 3.38Å; L287-V316 HydrophobicContact CB-CG1 4.48Å; L287-V316 HydrophobicContact CD1-CG1 3.23Å; L287-V316 HydrophobicContact CG-CG1 4.45Å; I306-V316 HydrophobicContact CG2-CG1 4.5Å; V310-V316 HydrophobicContact CG2-CB 4.06Å; V310-V316 HydrophobicContact CG2-CG2 3.62Å; L314-V316 HydrophobicContact CD2-CG2 3.38Å; V316-V342 HydrophobicContact CB-CB 4.46Å; V316-V342 HydrophobicContact CB-CG1 4.14Å; V316-V342 HydrophobicContact CB-CG2 4.06Å; V316-V342 HydrophobicContact CG1-CB 4.41Å; V316-V342 HydrophobicContact CG1-CG1 3.79Å; V316-V342 HydrophobicContact CG1-CG2 3.9Å; V316-L343 PolarHBondContact O-N 3.18Å
317V95.9Very high93.7Very high1 Ų151 Ų511%0.00625%0.253CS..EExtended strand (participates in β ladder)trans-122.7124.1-177.7-175.20000109.1V285 V286 L287 I315 L343 L357 M375V285-V317 PolarHBondContact O-N 2.86Å; V286-V317 CarbonylContact C-O 3.52Å; V286-V317 WeakPolarHBondContact CA-O 3.3Å; L287-V317 PolarHBondContact N-O 3.21Å; I315-V317 HydrophobicContact CG2-CG2 4.15Å; V317-L343 WeakPolarHBondContact CA-O 3.49Å; V317-L357 HydrophobicContact CG2-CD1 4.31Å; V317-M375 HydrophobicContact CG1-CE 4.33Å; V317-M375 HydrophobicContact CG2-CE 3.75Å
318N95.2Very high93Very high4 Ų450.2 Ų50.22%0.02125%0.25CS..EExtended strand (participates in β ladder)trans-89.8118.5178.7-174.76.9000110.9T289 G293 V327 L337 V342 L343 G345T289-N318 WeakPolarHBondContact CB-OD1 3.28Å; T289-N318 WeakPolarHBondContact CG2-OD1 3.46Å; T289-N318 PolarHBondContact OG1-OD1 2.94Å; G293-N318 PolarHBondContact O-ND2 3.27Å; N318-V327 WeakPolarHBondContact O-CG2 3.37Å; N318-L337 WeakPolarHBondContact ND2-CD1 3.45Å; N318-V342 HydrophobicContact CB-CG1 3.78Å; N318-L343 PolarHBondContact N-O 3.12Å; N318-G345 VanDerWaalsContact O-CA 3.27Å; N318-G345 WeakPolarHBondContact O-CA 3.4Å; N318-G345 PolarHBondContact O-N 3.31Å
319C95.1Very high92Very high1 Ų149.6 Ų49.61%0.00725%0.252CS..EExtended strand (participates in β ladder)trans-115.9151.5171.8-74.40000110.2V286 L287 Q288 T289 A353V286-C319 HydrophobicContact CG1-CB 4.18Å; L287-C319 PolarHBondContact O-N 2.86Å; Q288-C319 CarbonylContact C-O 3.56Å; Q288-C319 VanDerWaalsContact CA-O 3.28Å; Q288-C319 WeakPolarHBondContact CA-O 3.11Å; T289-C319 PolarHBondContact N-O 3.19Å; T289-C319 PolarHBondContact OG1-O 3.35Å; C319-A353 WeakPolarHBondContact SG-CB 3.49Å
320S94.8Very high91.1Very high17 Ų1753.1 Ų53.112%0.11928%0.281CS..EExtended strand (participates in β ladder)trans-74.1148.6173-174.70000111.3G291 C322G291-S320 WeakPolarHBondContact O-CB 3.3Å; G291-S320 PolarHBondContact O-OG 3.26Å; S320-C322 VanDerWaalsContact C-N 3.28Å; S320-C322 VanDerWaalsContact OG-CB 3.27Å; S320-C322 WeakPolarHBondContact OG-CB 3.3Å; S320-C322 PolarHBondContact OG-N 2.84Å
321Q95.4Very high89.9Confident45 Ų4559.2 Ų59.221%0.2130%0.304CS..SBendtrans-75.2-18.7163.4-71.9172.925.400113R246 I247 Q288 T289R246-Q321 HydrophobicContact CG-CG 4.4Å; I247-Q321 PolarHBondContact O-NE2 3.07Å; Q288-Q321 HydrophobicContact CB-CG 3.68Å; Q288-Q321 PolarHBondContact O-NE2 3.45Å; T289-Q321 WeakPolarHBondContact O-CB 3.49Å; T289-Q321 VanDerWaalsContact O-CG 3.25Å; T289-Q321 WeakPolarHBondContact O-CG 3.37Å; T289-Q321 PolarHBondContact O-N 3.22Å
322C94.7Very high88.9Confident66 Ų6658.7 Ų58.745%0.44631%0.308SS..SBendtrans-70.3139.8177.9-61.60000109.9S320 R324S320-C322 VanDerWaalsContact C-N 3.28Å; S320-C322 VanDerWaalsContact OG-CB 3.27Å; S320-C322 WeakPolarHBondContact OG-CB 3.3Å; S320-C322 PolarHBondContact OG-N 2.84Å; C322-R324 VanDerWaalsContact C-N 3.3Å; C322-R324 PolarHBondContact O-N 2.86Å
323L92.6Very high87.7Confident95 Ų9554.9 Ų54.950%0.49729%0.289SS..SBendtrans-61.9-39.6177.717860.5000111.9T191 P204T191-L323 HydrophobicContact CG2-CD1 3.36Å; P204-L323 HydrophobicContact CB-CD1 4.08Å; P204-L323 HydrophobicContact CB-CG 3.97Å; P204-L323 WeakPolarHBondContact CB-O 3.37Å; P204-L323 HydrophobicContact CG-CD1 4.02Å; P204-L323 HydrophobicContact CG-CG 4.44Å; P204-L323 WeakPolarHBondContact CG-O 3.23Å
324R92.1Very high86.7Confident199 Ų19953.7 Ų53.775%0.75128%0.277SS*.SBendtrans-122.6146.8-177.6-175.1171.4-175.7-179.41.2111.2P204 C322P204-R324 HydrophobicContact CB-CB 4.33Å; P204-R324 WeakPolarHBondContact O-CD 3.49Å; P204-R324 WeakPolarHBondContact O-CG 3.34Å; C322-R324 VanDerWaalsContact C-N 3.3Å; C322-R324 PolarHBondContact O-N 2.86Å
325G88.4Confident86.1Confident37 Ų3759.2 Ų59.238%0.38130%0.297SS..SBendtrans116.2-169.4179.100000111.8N205 D347N205-G325 PolarHBondContact ND2-O 2.8Å; N205-G325 PolarHBondContact OD1-N 2.9Å; N205-G325 PolarHBondContact OD1-O 3.46Å; G325-D347 WeakPolarHBondContact O-CB 3.37Å
326R87.9Confident85.7Confident132 Ų13260.7 Ų60.750%0.49830%0.304SS..  trans-133.4156-179.370.6-176.6-171-167.32.8110.3D328 S346 D347R326-D328 IonicContact CZ-OD2 2.69Å; R326-D328 IonicContact NE-OD2 3.91Å; R326-D328 PolarHBondContact NE-OD2 2.77Å; R326-D328 IonicContact NH2-OD2 3.83Å; R326-D328 PolarHBondContact NH2-OD2 3.18Å; R326-D328 PolarHBondContact O-N 3.12Å; R326-S346 CarbonylContact C-O 3.58Å; R326-S346 VanDerWaalsContact CA-O 3.31Å; R326-S346 WeakPolarHBondContact CA-O 3.45Å; R326-D347 HydrophobicContact CB-CB 4.05Å
327V86Confident85.4Confident9 Ų960.7 Ų60.76%0.05530%0.304CS..  trans-68.4124.8163.6173.90000108.9A292 N318 Y344 S346A292-V327 CarbonylContact O-C 3.55Å; A292-V327 VanDerWaalsContact O-CA 3.31Å; A292-V327 WeakPolarHBondContact O-CA 3.49Å; N318-V327 WeakPolarHBondContact O-CG2 3.37Å; V327-Y344 HydrophobicContact CG1-CD1 3.72Å; V327-Y344 HydrophobicContact CG1-CE1 4.4Å; V327-S346 PolarHBondContact N-O 2.96Å
328D79.3Confident85Confident47 Ų4762.4 Ų62.425%0.25131%0.313SS..  trans-130.7123.2-176.8-162.2-47.9000109.9A292 R326 A330A292-D328 HydrophobicContact CB-CB 4.29Å; A292-D328 PolarHBondContact O-N 3.01Å; R326-D328 IonicContact CZ-OD2 2.69Å; R326-D328 IonicContact NE-OD2 3.91Å; R326-D328 PolarHBondContact NE-OD2 2.77Å; R326-D328 IonicContact NH2-OD2 3.83Å; R326-D328 PolarHBondContact NH2-OD2 3.18Å; R326-D328 PolarHBondContact O-N 3.12Å; D328-A330 PolarHBondContact O-N 2.82Å; D328-A330 VanDerWaalsContact O-N 3.15Å; D328-A330 WeakPolarHBondContact OD1-CB 3.32Å; D328-A330 PolarHBondContact OD1-N 3.32Å; D328-A330 VanDerWaalsContact OD1-N 3.15Å
329P71.9Confident84.7Confident49 Ų4967 Ų6732%0.31834%0.338SS..THydrogen-bonded Turntrans-77.411-176.731.5-35.7000115.9Y331 I338 Y344P329-Y331 PolarHBondContact O-N 2.9Å; P329-Y331 VanDerWaalsContact O-N 3.14Å; P329-I338 HydrophobicContact CB-CD1 3.78Å; P329-Y344 HydrophobicContact CB-CE1 3.71Å; P329-Y344 WeakPolarHBondContact CB-OH 3.32Å; P329-Y344 HydrophobicContact CG-CE1 4.02Å; P329-Y344 WeakPolarHBondContact CG-OH 3.37Å
330A73.7Confident84.6Confident80 Ų8067.1 Ų67.166%0.66134%0.339SS*.THydrogen-bonded Turntrans-59.1-23.4-178.500000114.5D328D328-A330 PolarHBondContact O-N 2.82Å; D328-A330 VanDerWaalsContact O-N 3.15Å; D328-A330 WeakPolarHBondContact OD1-CB 3.32Å; D328-A330 PolarHBondContact OD1-N 3.32Å; D328-A330 VanDerWaalsContact OD1-N 3.15Å
331Y72.3Confident84.5Confident139 Ų13967.7 Ų67.755%0.54535%0.347SS..SBendtrans-97142.7-178.6-61.8-81.8000112.2A292 N294 P329 T333 G334 R335A292-Y331 HydrophobicContact CB-CD2 4.18Å; A292-Y331 HydrophobicContact CB-CE2 4.05Å; N294-Y331 WeakPolarHBondContact OD1-CB 3.38Å; P329-Y331 PolarHBondContact O-N 2.9Å; P329-Y331 VanDerWaalsContact O-N 3.14Å; Y331-T333 PolarHBondContact O-N 3.29Å; Y331-G334 WeakPolarHBondContact O-CA 3.37Å; Y331-G334 PolarHBondContact O-N 2.91Å; Y331-R335 PolarHBondContact O-N 3.39Å
332E72.7Confident84.5Confident151 Ų15165.9 Ų65.971%0.70634%0.339SS*.Hα-helixtrans-51.3-44.4173-177.2-174.2-172.500111.8G334 R335 I336E332-G334 PolarHBondContact O-N 3.45Å; E332-R335 WeakPolarHBondContact O-CB 3.35Å; E332-R335 PolarHBondContact O-N 3.23Å; E332-I336 PolarHBondContact O-N 2.89Å
333T68.9Low84.4Confident39 Ų3964 Ų6424%0.23933%0.325CS..Hα-helixtrans-64.3-18.9177.348.70000114.6N294 M295 Y331 I336N294-T333 WeakPolarHBondContact CB-OG1 3.41Å; N294-T333 PolarHBondContact OD1-OG1 2.79Å; M295-T333 PolarHBondContact N-O 3.28Å; M295-T333 WeakPolarHBondContact O-CB 2.85Å; Y331-T333 PolarHBondContact O-N 3.29Å; T333-I336 WeakPolarHBondContact O-CD1 3.47Å; T333-I336 WeakPolarHBondContact O-CG1 3.34Å
334G73.7Confident84.3Confident2 Ų262.8 Ų62.82%0.02131%0.314CS..Hα-helixtrans-87.1-42.616900000110.8N294 Y331 E332 I336 L337 I338N294-G334 PolarHBondContact OD1-N 3.01Å; Y331-G334 WeakPolarHBondContact O-CA 3.37Å; Y331-G334 PolarHBondContact O-N 2.91Å; E332-G334 PolarHBondContact O-N 3.45Å; G334-I336 VanDerWaalsContact C-N 3.31Å; G334-I336 PolarHBondContact O-N 3.14Å; G334-L337 PolarHBondContact O-N 3.31Å; G334-L337 VanDerWaalsContact O-N 3.13Å; G334-I338 VanDerWaalsContact O-CD1 3.22Å; G334-I338 WeakPolarHBondContact O-CD1 3.11Å
335R83.5Confident84.2Confident128 Ų12853.3 Ų53.348%0.48328%0.278SS..Hα-helixtrans-54.1-42.2-176-170.266-167.7-154.5-1.9113.4Y331 E332 L337 I338 D339Y331-R335 PolarHBondContact O-N 3.39Å; E332-R335 WeakPolarHBondContact O-CB 3.35Å; E332-R335 PolarHBondContact O-N 3.23Å; R335-L337 PolarHBondContact O-N 2.74Å; R335-L337 VanDerWaalsContact O-N 3.14Å; R335-I338 WeakPolarHBondContact O-CB 3.11Å; R335-I338 PolarHBondContact O-N 2.86Å; R335-D339 IonicContact CZ-OD1 3.48Å; R335-D339 IonicContact NE-OD1 3.32Å; R335-D339 PolarHBondContact NE-OD1 2.69Å; R335-D339 IonicContact NE-OD2 3.32Å; R335-D339 IonicContact NH2-OD1 2.66Å; R335-D339 PolarHBondContact O-N 2.74Å
336I88.3Confident84.3Confident32 Ų3252.6 Ų52.616%0.16427%0.267CS..Hα-helixtrans-52.8-35.5178.759.9-178.6000113.8I303 E332 T333 G334 I338 A340I303-I336 HydrophobicContact CD1-CD1 3.82Å; I303-I336 HydrophobicContact CD1-CG1 4.14Å; I303-I336 HydrophobicContact CG1-CD1 4.25Å; E332-I336 PolarHBondContact O-N 2.89Å; T333-I336 WeakPolarHBondContact O-CD1 3.47Å; T333-I336 WeakPolarHBondContact O-CG1 3.34Å; G334-I336 VanDerWaalsContact C-N 3.31Å; G334-I336 PolarHBondContact O-N 3.14Å; I336-I338 VanDerWaalsContact C-N 3.34Å; I336-A340 WeakPolarHBondContact O-CB 3.33Å; I336-A340 PolarHBondContact O-N 2.97Å
337L91.1Very high84.6Confident1 Ų147 Ų471%0.00525%0.247CC..Hα-helixtrans-71.7-34-179.8-69.5174000111.2T289 M295 I303 I306 N318 G334 R335 A340 G341 V342T289-L337 HydrophobicContact CG2-CD1 3.89Å; M295-L337 HydrophobicContact CB-CD1 4.11Å; M295-L337 HydrophobicContact CB-CD2 4.39Å; M295-L337 HydrophobicContact CB-CG 4.38Å; M295-L337 HydrophobicContact SD-CD2 3.97Å; I303-L337 HydrophobicContact CD1-CD2 3.92Å; I306-L337 HydrophobicContact CD1-CD2 3.95Å; N318-L337 WeakPolarHBondContact ND2-CD1 3.45Å; G334-L337 PolarHBondContact O-N 3.31Å; G334-L337 VanDerWaalsContact O-N 3.13Å; R335-L337 PolarHBondContact O-N 2.74Å; R335-L337 VanDerWaalsContact O-N 3.14Å; L337-A340 CarbonylContact O-C 3.57Å; L337-A340 WeakPolarHBondContact O-CB 3.48Å; L337-A340 PolarHBondContact O-N 3.37Å; L337-G341 PolarHBondContact O-N 2.58Å; L337-V342 HydrophobicContact CB-CB 4.09Å; L337-V342 HydrophobicContact CB-CG2 4.18Å; L337-V342 HydrophobicContact CD2-CG2 4.3Å; L337-V342 WeakPolarHBondContact O-CB 3.04Å; L337-V342 VanDerWaalsContact O-CG2 3.25Å; L337-V342 WeakPolarHBondContact O-CG2 3.36Å; L337-V342 PolarHBondContact O-N 3.16Å
338I87Confident85.1Confident38 Ų3847.1 Ų47.120%0.19525%0.248CC..Hα-helixtrans-74.8-41-179.6-59.8126000110.2P329 G334 R335 I336 A340 G341 Y344P329-I338 HydrophobicContact CB-CD1 3.78Å; G334-I338 VanDerWaalsContact O-CD1 3.22Å; G334-I338 WeakPolarHBondContact O-CD1 3.11Å; R335-I338 WeakPolarHBondContact O-CB 3.11Å; R335-I338 PolarHBondContact O-N 2.86Å; I336-I338 VanDerWaalsContact C-N 3.34Å; I338-A340 PolarHBondContact O-N 3.49Å; I338-G341 VanDerWaalsContact O-CA 3.31Å; I338-G341 WeakPolarHBondContact O-CA 3.49Å; I338-G341 PolarHBondContact O-N 2.87Å; I338-Y344 HydrophobicContact CD1-CD1 4.47Å; I338-Y344 HydrophobicContact CD1-CE1 3.29Å; I338-Y344 HydrophobicContact CD1-CE2 4.47Å; I338-Y344 WeakPolarHBondContact CD1-OH 3.3Å; I338-Y344 HydrophobicContact CG1-CD1 4.22Å; I338-Y344 HydrophobicContact CG1-CE1 3.32Å; I338-Y344 HydrophobicContact CG1-CE2 3.95Å; I338-Y344 WeakPolarHBondContact CG1-OH 3.35Å; I338-Y344 HydrophobicContact CG2-CE2 4.32Å
339D90.2Very high85.9Confident100 Ų10045.4 Ų45.454%0.53524%0.239SC..Hα-helixtrans-63.7-31.9173.8-60.8-16.6000110.1R335 G341R335-D339 IonicContact CZ-OD1 3.48Å; R335-D339 IonicContact NE-OD1 3.32Å; R335-D339 PolarHBondContact NE-OD1 2.69Å; R335-D339 IonicContact NE-OD2 3.32Å; R335-D339 IonicContact NH2-OD1 2.66Å; R335-D339 PolarHBondContact O-N 2.74Å; D339-G341 PolarHBondContact O-N 2.63Å
340A92.2Very high87.2Confident4 Ų444.1 Ų44.13%0.03323%0.23CC..THydrogen-bonded Turntrans-71.1-10.8169.300000114.2I303 I306 H307 I336 L337 I338I303-A340 HydrophobicContact CG2-CB 4.07Å; I306-A340 HydrophobicContact CG2-CB 4.5Å; H307-A340 HydrophobicContact CB-CB 3.92Å; H307-A340 PolarHBondContact ND1-O 3.16Å; I336-A340 WeakPolarHBondContact O-CB 3.33Å; I336-A340 PolarHBondContact O-N 2.97Å; L337-A340 CarbonylContact O-C 3.57Å; L337-A340 WeakPolarHBondContact O-CB 3.48Å; L337-A340 PolarHBondContact O-N 3.37Å; I338-A340 PolarHBondContact O-N 3.49Å
341G93.3Very high88.3Confident29 Ų2941 Ų4130%0.29920%0.201SC..THydrogen-bonded Turntrans92.815177.200000115.4V310 L337 I338 D339V310-G341 WeakPolarHBondContact CG1-O 3.08Å; L337-G341 PolarHBondContact O-N 2.58Å; I338-G341 VanDerWaalsContact O-CA 3.31Å; I338-G341 WeakPolarHBondContact O-CA 3.49Å; I338-G341 PolarHBondContact O-N 2.87Å; D339-G341 PolarHBondContact O-N 2.63Å
342V94.6Very high89.6Confident6 Ų634.3 Ų34.34%0.03618%0.175CC..PPolyproline II helixtrans-71.8136.8174.1-179.50000110.5I306 V316 N318 L337I306-V342 HydrophobicContact CG2-CG2 3.38Å; V316-V342 HydrophobicContact CB-CB 4.46Å; V316-V342 HydrophobicContact CB-CG1 4.14Å; V316-V342 HydrophobicContact CB-CG2 4.06Å; V316-V342 HydrophobicContact CG1-CB 4.41Å; V316-V342 HydrophobicContact CG1-CG1 3.79Å; V316-V342 HydrophobicContact CG1-CG2 3.9Å; N318-V342 HydrophobicContact CB-CG1 3.78Å; L337-V342 HydrophobicContact CB-CB 4.09Å; L337-V342 HydrophobicContact CB-CG2 4.18Å; L337-V342 HydrophobicContact CD2-CG2 4.3Å; L337-V342 WeakPolarHBondContact O-CB 3.04Å; L337-V342 VanDerWaalsContact O-CG2 3.25Å; L337-V342 WeakPolarHBondContact O-CG2 3.36Å; L337-V342 PolarHBondContact O-N 3.16Å
343L93.6Very high90.8Very high27 Ų2727.1 Ų27.114%0.14114%0.142CC..EExtended strand (participates in β ladder)trans-80.5148.3177-56.9-179.5000111.7I315 V316 V317 N318 K372 M375I315-L343 HydrophobicContact CG2-CD1 3.76Å; V316-L343 PolarHBondContact O-N 3.18Å; V317-L343 WeakPolarHBondContact CA-O 3.49Å; N318-L343 PolarHBondContact N-O 3.12Å; L343-K372 HydrophobicContact CD1-CB 4.09Å; L343-K372 HydrophobicContact CD1-CG 4.13Å; L343-K372 HydrophobicContact CD2-CB 4.19Å; L343-K372 HydrophobicContact CD2-CG 4.38Å; L343-M375 HydrophobicContact CD1-CB 3.69Å; L343-M375 HydrophobicContact CD1-CG 4.19Å
344Y88.8Confident92.1Very high70 Ų7026.2 Ų26.228%0.27514%0.135SC..EExtended strand (participates in β ladder)trans-79.8127.1171.7-57.1-74.6000111.6V327 P329 I338 S346V327-Y344 HydrophobicContact CG1-CD1 3.72Å; V327-Y344 HydrophobicContact CG1-CE1 4.4Å; P329-Y344 HydrophobicContact CB-CE1 3.71Å; P329-Y344 WeakPolarHBondContact CB-OH 3.32Å; P329-Y344 HydrophobicContact CG-CE1 4.02Å; P329-Y344 WeakPolarHBondContact CG-OH 3.37Å; I338-Y344 HydrophobicContact CD1-CD1 4.47Å; I338-Y344 HydrophobicContact CD1-CE1 3.29Å; I338-Y344 HydrophobicContact CD1-CE2 4.47Å; I338-Y344 WeakPolarHBondContact CD1-OH 3.3Å; I338-Y344 HydrophobicContact CG1-CD1 4.22Å; I338-Y344 HydrophobicContact CG1-CE1 3.32Å; I338-Y344 HydrophobicContact CG1-CE2 3.95Å; I338-Y344 WeakPolarHBondContact CG1-OH 3.35Å; I338-Y344 HydrophobicContact CG2-CE2 4.32Å; Y344-S346 VanDerWaalsContact C-N 3.25Å; Y344-S346 PolarHBondContact O-N 3.48Å
345G90.1Very high93.3Very high0 Ų026.2 Ų26.20%014%0.135CC..  trans-79.8-2.3168.700000114.1N318 D347 L348N318-G345 VanDerWaalsContact O-CA 3.27Å; N318-G345 WeakPolarHBondContact O-CA 3.4Å; N318-G345 PolarHBondContact O-N 3.31Å; G345-D347 PolarHBondContact O-N 3.45Å; G345-D347 VanDerWaalsContact O-N 3.14Å; G345-L348 VanDerWaalsContact O-CB 3.23Å; G345-L348 WeakPolarHBondContact O-CB 3.33Å; G345-L348 WeakPolarHBondContact O-CD1 3.3Å; G345-L348 WeakPolarHBondContact O-CG 3.34Å; G345-L348 PolarHBondContact O-N 3.23Å
346S91.6Very high94Very high22 Ų2220.1 Ų20.115%0.15411%0.112CC..THydrogen-bonded Turntrans48.9-117.3-173.7-169.60000111.1R326 V327 Y344 T384R326-S346 CarbonylContact C-O 3.58Å; R326-S346 VanDerWaalsContact CA-O 3.31Å; R326-S346 WeakPolarHBondContact CA-O 3.45Å; V327-S346 PolarHBondContact N-O 2.96Å; Y344-S346 VanDerWaalsContact C-N 3.25Å; Y344-S346 PolarHBondContact O-N 3.48Å; S346-T384 PolarHBondContact OG-O 3.47Å
347D94.2Very high94.5Very high13 Ų1318.6 Ų18.67%0.0710%0.104CC..THydrogen-bonded Turntrans-108.522.9-178.768.8-26000113.4R189 N205 G325 R326 G345 T384R189-D347 IonicContact CZ-OD2 3.6Å; R189-D347 IonicContact NH1-OD1 3.84Å; R189-D347 PolarHBondContact NH1-OD1 2.94Å; R189-D347 IonicContact NH1-OD2 2.69Å; R189-D347 PolarHBondContact NH1-OD2 3.06Å; R189-D347 IonicContact NH2-OD2 3.91Å; N205-D347 HydrophobicContact CB-CB 4.12Å; N205-D347 PolarHBondContact ND2-O 2.93Å; G325-D347 WeakPolarHBondContact O-CB 3.37Å; R326-D347 HydrophobicContact CB-CB 4.05Å; G345-D347 PolarHBondContact O-N 3.45Å; G345-D347 VanDerWaalsContact O-N 3.14Å; D347-T384 PolarHBondContact OD1-N 3.12Å; D347-T384 VanDerWaalsContact OD2-CB 3.24Å; D347-T384 WeakPolarHBondContact OD2-CB 3.44Å; D347-T384 PolarHBondContact OD2-OG1 3.29Å
348L95.6Very high94.8Very high13 Ų1318.6 Ų18.67%0.06810%0.104CC..  trans-57.3139.2172.3-77.7169.1000111.4G345 A352 A353 E382 L383G345-L348 VanDerWaalsContact O-CB 3.23Å; G345-L348 WeakPolarHBondContact O-CB 3.33Å; G345-L348 WeakPolarHBondContact O-CD1 3.3Å; G345-L348 WeakPolarHBondContact O-CG 3.34Å; G345-L348 PolarHBondContact O-N 3.23Å; L348-A352 HydrophobicContact CD2-CB 3.97Å; L348-A353 HydrophobicContact CB-CB 4.23Å; L348-A353 HydrophobicContact CD1-CB 4.13Å; L348-E382 HydrophobicContact CD2-CB 3.96Å; L348-E382 HydrophobicContact CD2-CG 3.4Å; L348-L383 HydrophobicContact CD1-CD1 4.22Å; L348-L383 HydrophobicContact CD2-CB 4.21Å; L348-L383 HydrophobicContact CG-CB 4.33Å; L348-L383 HydrophobicContact CG-CD1 4.09Å
349T97.6Very high95.4Very high11 Ų1117.1 Ų17.17%0.06710%0.096CC..  trans-71.6161.8159.769.60000110P204 E351 A352 A353P204-T349 HydrophobicContact CG-CG2 4.46Å; T349-E351 VanDerWaalsContact C-N 3.3Å; T349-E351 WeakPolarHBondContact CB-OE2 3.48Å; T349-E351 PolarHBondContact O-N 3.44Å; T349-E351 PolarHBondContact OG1-OE2 2.77Å; T349-A352 PolarHBondContact O-N 3.17Å; T349-A352 WeakPolarHBondContact OG1-CB 3.49Å; T349-A352 PolarHBondContact OG1-N 2.71Å; T349-A353 WeakPolarHBondContact O-CB 3.29Å; T349-A353 PolarHBondContact O-N 2.72Å
350V97.1Very high95.8Very high21 Ų2112.4 Ų12.413%0.1277%0.071CC..Hα-helixtrans-65.6-40.5-178.9177.90000110.8L244 Q288 A353 L354L244-V350 HydrophobicContact CD1-CG1 3.56Å; L244-V350 HydrophobicContact CD2-CG1 3.66Å; L244-V350 HydrophobicContact CG-CG1 4.27Å; Q288-V350 HydrophobicContact CG-CG2 4.2Å; V350-A353 PolarHBondContact O-N 3.49Å; V350-L354 HydrophobicContact CG1-CD1 3.9Å; V350-L354 HydrophobicContact CG1-CG 4.5Å; V350-L354 WeakPolarHBondContact O-CB 3.26Å; V350-L354 WeakPolarHBondContact O-CG 3.45Å; V350-L354 PolarHBondContact O-N 3.04Å
351E98.1Very high96Very high14 Ų1412.7 Ų12.77%0.0657%0.072CC..Hα-helixtrans-58-50.3177.3-58.690.315400109.9C124 Y125 T191 T349 T355C124-E351 HydrophobicContact CB-CB 4.33Å; C124-E351 HydrophobicContact CB-CG 3.83Å; Y125-E351 HydrophobicContact CD1-CB 4.03Å; Y125-E351 HydrophobicContact CD1-CG 4Å; Y125-E351 HydrophobicContact CD2-CG 3.82Å; Y125-E351 HydrophobicContact CE1-CB 4.18Å; Y125-E351 HydrophobicContact CE1-CG 3.88Å; Y125-E351 HydrophobicContact CE2-CG 3.69Å; Y125-E351 HydrophobicContact CG-CB 4.25Å; Y125-E351 HydrophobicContact CG-CG 3.98Å; T191-E351 WeakPolarHBondContact CA-OE1 3.41Å; T191-E351 VanDerWaalsContact CB-OE1 3.23Å; T191-E351 WeakPolarHBondContact CB-OE1 3.21Å; T191-E351 PolarHBondContact OG1-OE1 3.18Å; T349-E351 VanDerWaalsContact C-N 3.3Å; T349-E351 WeakPolarHBondContact CB-OE2 3.48Å; T349-E351 PolarHBondContact O-N 3.44Å; T349-E351 PolarHBondContact OG1-OE2 2.77Å; E351-T355 WeakPolarHBondContact O-CG2 3.48Å; E351-T355 PolarHBondContact O-N 3.37Å; E351-T355 VanDerWaalsContact O-N 3.09Å; E351-T355 PolarHBondContact O-OG1 2.77Å; E351-T355 VanDerWaalsContact O-OG1 3.06Å
352A98.4Very high96.2Very high0 Ų012.6 Ų12.60%07%0.071CC..Hα-helixtrans-67-39.7177.400000112.6F132 N188 L348 T349 T355 K356 E382F132-A352 WeakPolarHBondContact CE2-O 3.33Å; N188-A352 HydrophobicContact CB-CB 4.34Å; N188-A352 VanDerWaalsContact O-CB 3.23Å; N188-A352 WeakPolarHBondContact O-CB 3.44Å; L348-A352 HydrophobicContact CD2-CB 3.97Å; T349-A352 PolarHBondContact O-N 3.17Å; T349-A352 WeakPolarHBondContact OG1-CB 3.49Å; T349-A352 PolarHBondContact OG1-N 2.71Å; A352-T355 PolarHBondContact O-OG1 3.28Å; A352-K356 WeakPolarHBondContact O-CB 3.4Å; A352-K356 PolarHBondContact O-N 2.99Å; A352-E382 HydrophobicContact CB-CB 4.42Å
353A98.1Very high96.3Very high0 Ų013.9 Ų13.90%08%0.075CC..Hα-helixtrans-62.4-45.8178.200000112V286 C319 L348 T349 V350 L357V286-A353 HydrophobicContact CG1-CB 3.98Å; V286-A353 HydrophobicContact CG2-CB 3.93Å; C319-A353 WeakPolarHBondContact SG-CB 3.49Å; L348-A353 HydrophobicContact CB-CB 4.23Å; L348-A353 HydrophobicContact CD1-CB 4.13Å; T349-A353 WeakPolarHBondContact O-CB 3.29Å; T349-A353 PolarHBondContact O-N 2.72Å; V350-A353 PolarHBondContact O-N 3.49Å; A353-L357 WeakPolarHBondContact O-CB 3.37Å; A353-L357 PolarHBondContact O-N 3.14Å
354L97.9Very high96.3Very high19 Ų1917.4 Ų17.410%0.09911%0.108CC..Hα-helixtrans-65.8-48.2179-76.9166.2000111.8Y125 I242 L244 V286 V350 L357 A358Y125-L354 HydrophobicContact CE1-CD1 3.87Å; I242-L354 HydrophobicContact CD1-CB 4.18Å; I242-L354 HydrophobicContact CD1-CD2 4.05Å; I242-L354 VanDerWaalsContact CD1-O 3.27Å; I242-L354 WeakPolarHBondContact CD1-O 3.45Å; L244-L354 HydrophobicContact CB-CD1 4.11Å; L244-L354 HydrophobicContact CB-CD2 4.1Å; L244-L354 HydrophobicContact CD1-CD1 4.33Å; L244-L354 HydrophobicContact CD2-CD1 4.24Å; L244-L354 HydrophobicContact CG-CD1 4.46Å; V286-L354 HydrophobicContact CB-CD2 3.98Å; V286-L354 HydrophobicContact CB-CG 4.3Å; V286-L354 HydrophobicContact CG2-CD2 3.71Å; V286-L354 HydrophobicContact CG2-CG 3.95Å; V350-L354 HydrophobicContact CG1-CD1 3.9Å; V350-L354 HydrophobicContact CG1-CG 4.5Å; V350-L354 WeakPolarHBondContact O-CB 3.26Å; V350-L354 WeakPolarHBondContact O-CG 3.45Å; V350-L354 PolarHBondContact O-N 3.04Å; L354-L357 PolarHBondContact O-N 2.91Å; L354-A358 PolarHBondContact O-N 2.91Å
355T98.2Very high96.6Very high3 Ų318.8 Ų18.82%0.01812%0.12CC..Hα-helixtrans-72-33.1-177.861.50000112.2W97 S128 A129 F132 E351 A352 A358 Y359W97-T355 HydrophobicContact CH2-CG2 4.22Å; W97-T355 HydrophobicContact CZ3-CG2 4.37Å; S128-T355 WeakPolarHBondContact CB-OG1 3.36Å; S128-T355 PolarHBondContact O-OG1 3.29Å; A129-T355 HydrophobicContact CB-CG2 3.83Å; F132-T355 WeakPolarHBondContact CD2-OG1 3.48Å; F132-T355 VanDerWaalsContact CE2-OG1 3.29Å; F132-T355 WeakPolarHBondContact CE2-OG1 3.46Å; E351-T355 WeakPolarHBondContact O-CG2 3.48Å; E351-T355 PolarHBondContact O-N 3.37Å; E351-T355 VanDerWaalsContact O-N 3.09Å; E351-T355 PolarHBondContact O-OG1 2.77Å; E351-T355 VanDerWaalsContact O-OG1 3.06Å; A352-T355 PolarHBondContact O-OG1 3.28Å; T355-A358 PolarHBondContact O-N 2.9Å; T355-Y359 WeakPolarHBondContact O-CB 3.32Å; T355-Y359 PolarHBondContact O-N 3.24Å
356K98.4Very high96.9Very high0 Ų020.2 Ų20.20%013%0.128CC..Hα-helixtrans-62.1-45170.4-167.9175.8-178.6-179.30110.7F132 A352 Y359 V360 L374 M375 Q377 I379 E382F132-K356 HydrophobicContact CD1-CB 4.48Å; F132-K356 HydrophobicContact CD1-CG 4.28Å; F132-K356 HydrophobicContact CD2-CB 4.16Å; F132-K356 HydrophobicContact CE1-CB 3.95Å; F132-K356 HydrophobicContact CE1-CD 4.02Å; F132-K356 HydrophobicContact CE1-CG 3.75Å; F132-K356 HydrophobicContact CE2-CB 3.6Å; F132-K356 HydrophobicContact CE2-CG 4.33Å; F132-K356 HydrophobicContact CZ-CB 3.49Å; F132-K356 VanDerWaalsContact CZ-CB 3.49Å; F132-K356 HydrophobicContact CZ-CD 4.03Å; F132-K356 HydrophobicContact CZ-CG 3.81Å; A352-K356 WeakPolarHBondContact O-CB 3.4Å; A352-K356 PolarHBondContact O-N 2.99Å; K356-Y359 PolarHBondContact O-N 3.45Å; K356-V360 HydrophobicContact CG-CG2 4.26Å; K356-V360 WeakPolarHBondContact O-CB 3.38Å; K356-V360 VanDerWaalsContact O-CG2 3.3Å; K356-V360 WeakPolarHBondContact O-CG2 3.45Å; K356-V360 PolarHBondContact O-N 2.88Å; K356-L374 VanDerWaalsContact CE-O 3.26Å; K356-L374 WeakPolarHBondContact CE-O 3.48Å; K356-L374 PolarHBondContact NZ-O 3.38Å; K356-M375 HydrophobicContact CB-CE 4.15Å; K356-M375 HydrophobicContact CB-SD 4.34Å; K356-M375 HydrophobicContact CD-CE 3.89Å; K356-M375 HydrophobicContact CD-SD 4.22Å; K356-M375 WeakPolarHBondContact CE-O 3.43Å; K356-M375 HydrophobicContact CG-CE 3.96Å; K356-M375 HydrophobicContact CG-SD 3.82Å; K356-M375 PolarHBondContact NZ-O 3.25Å; K356-Q377 PolarHBondContact NZ-O 3.16Å; K356-I379 HydrophobicContact CG-CD1 4.32Å; K356-E382 HydrophobicContact CD-CG 4.26Å; K356-E382 VanDerWaalsContact CE-OE1 3.3Å; K356-E382 WeakPolarHBondContact CE-OE1 3.23Å; K356-E382 IonicContact NZ-OE1 3.38Å; K356-E382 PolarHBondContact NZ-OE1 2.88Å
357L98.2Very high97.2Very high0 Ų022 Ų220%014%0.14CC..Hα-helixtrans-62-44177.7-17560.1000111.7I242 V286 I315 V317 A353 L354 Y359 V360 L361 M375I242-L357 HydrophobicContact CG2-CD2 4.16Å; I242-L357 HydrophobicContact CG2-CG 3.96Å; V286-L357 HydrophobicContact CG2-CD2 3.91Å; I315-L357 HydrophobicContact CB-CD1 4.03Å; I315-L357 HydrophobicContact CG2-CD1 3.76Å; V317-L357 HydrophobicContact CG2-CD1 4.31Å; A353-L357 WeakPolarHBondContact O-CB 3.37Å; A353-L357 PolarHBondContact O-N 3.14Å; L354-L357 PolarHBondContact O-N 2.91Å; L357-Y359 VanDerWaalsContact C-N 3.33Å; L357-Y359 PolarHBondContact O-N 2.77Å; L357-V360 PolarHBondContact O-N 2.87Å; L357-L361 HydrophobicContact CD1-CD1 3.91Å; L357-L361 HydrophobicContact CD1-CG 4.08Å; L357-L361 HydrophobicContact CG-CD1 3.9Å; L357-L361 HydrophobicContact CG-CG 4.47Å; L357-L361 WeakPolarHBondContact O-CB 3.39Å; L357-L361 VanDerWaalsContact O-CG 3.29Å; L357-L361 WeakPolarHBondContact O-CG 3.44Å; L357-L361 PolarHBondContact O-N 3.23Å; L357-M375 HydrophobicContact CB-CE 4.46Å; L357-M375 HydrophobicContact CB-SD 4.32Å; L357-M375 HydrophobicContact CD1-SD 4.17Å
358A98.4Very high97.3Very high0 Ų024.9 Ų24.90%016%0.155CC..Hα-helixtrans-57.2-46.2173.400000112F94 L238 D239 I242 L354 T355 G362F94-A358 HydrophobicContact CE1-CB 3.88Å; F94-A358 HydrophobicContact CZ-CB 4.47Å; L238-A358 HydrophobicContact CB-CB 4.23Å; D239-A358 WeakPolarHBondContact CB-O 3.4Å; D239-A358 PolarHBondContact N-O 2.82Å; D239-A358 VanDerWaalsContact O-CB 3.3Å; D239-A358 WeakPolarHBondContact O-CB 3.01Å; I242-A358 HydrophobicContact CD1-CB 3.92Å; L354-A358 PolarHBondContact O-N 2.91Å; T355-A358 PolarHBondContact O-N 2.9Å; A358-G362 PolarHBondContact O-N 2.84Å
359Y98.3Very high97.3Very high8 Ų828.9 Ų28.93%0.03118%0.183CC..Hα-helixtrans-63.9-49.9178.5161.8-94.7000111.9F132 E135 R235 T355 K356 L357 L361 G362 R363 L374 I379F132-Y359 HydrophobicContact CB-CD1 4.25Å; F132-Y359 HydrophobicContact CB-CD2 4.03Å; F132-Y359 HydrophobicContact CB-CG 3.77Å; F132-Y359 HydrophobicContact CG-CG 4.49Å; F132-Y359 WeakPolarHBondContact O-CD2 3.18Å; F132-Y359 WeakPolarHBondContact O-CE2 3.27Å; E135-Y359 WeakPolarHBondContact OE1-CE2 3.39Å; E135-Y359 PolarHBondContact OE1-OH 3.28Å; R235-Y359 HydrophobicContact CB-CE2 4.45Å; R235-Y359 HydrophobicContact CG-CE2 4.36Å; T355-Y359 WeakPolarHBondContact O-CB 3.32Å; T355-Y359 PolarHBondContact O-N 3.24Å; K356-Y359 PolarHBondContact O-N 3.45Å; L357-Y359 VanDerWaalsContact C-N 3.33Å; L357-Y359 PolarHBondContact O-N 2.77Å; Y359-L361 PolarHBondContact O-N 3.45Å; Y359-G362 PolarHBondContact O-N 3.13Å; Y359-R363 PolarHBondContact O-N 3.32Å; Y359-R363 PolarHBondContact OH-NH1 2.95Å; Y359-L374 HydrophobicContact CE1-CD2 4.11Å; Y359-I379 HydrophobicContact CD1-CD1 4.21Å; Y359-I379 HydrophobicContact CE1-CD1 3.82Å
360V98.1Very high97.3Very high0 Ų032.9 Ų32.90%020%0.201CC..Hα-helixtrans-63.6-42.8-178.3170.90000111.4K356 L357 G362 R363 K371 L374 M375K356-V360 HydrophobicContact CG-CG2 4.26Å; K356-V360 WeakPolarHBondContact O-CB 3.38Å; K356-V360 VanDerWaalsContact O-CG2 3.3Å; K356-V360 WeakPolarHBondContact O-CG2 3.45Å; K356-V360 PolarHBondContact O-N 2.88Å; L357-V360 PolarHBondContact O-N 2.87Å; V360-G362 VanDerWaalsContact C-N 3.29Å; V360-G362 PolarHBondContact O-N 2.87Å; V360-R363 WeakPolarHBondContact O-CB 3.44Å; V360-R363 PolarHBondContact O-N 3.48Å; V360-K371 HydrophobicContact CG1-CB 3.54Å; V360-K371 HydrophobicContact CG1-CD 4.49Å; V360-K371 HydrophobicContact CG1-CG 3.77Å; V360-K371 WeakPolarHBondContact CG1-O 3.46Å; V360-K371 WeakPolarHBondContact O-CE 3.4Å; V360-L374 HydrophobicContact CG1-CB 4.5Å; V360-L374 HydrophobicContact CG2-CB 4.26Å; V360-L374 HydrophobicContact CG2-CD2 3.86Å; V360-L374 HydrophobicContact CG2-CG 3.97Å; V360-M375 HydrophobicContact CB-CG 4.33Å; V360-M375 HydrophobicContact CB-SD 3.9Å; V360-M375 HydrophobicContact CG1-CG 4.11Å; V360-M375 HydrophobicContact CG1-SD 4.35Å; V360-M375 HydrophobicContact CG2-CG 4.2Å; V360-M375 HydrophobicContact CG2-SD 3.6Å; V360-M375 VanDerWaalsContact CG2-SD 3.6Å
361L97.8Very high97.4Very high10 Ų1033.1 Ų33.15%0.05220%0.2CC..Hα-helixtrans-66.9-34177.3-70.8171000112.1D239 I242 R283 I315 L357 Y359 R363 K371D239-L361 HydrophobicContact CB-CB 3.6Å; D239-L361 VanDerWaalsContact OD2-CB 3.25Å; D239-L361 WeakPolarHBondContact OD2-CB 3.31Å; I242-L361 HydrophobicContact CG2-CD1 3.68Å; R283-L361 HydrophobicContact CB-CD1 4.06Å; R283-L361 HydrophobicContact CB-CD2 4.27Å; I315-L361 HydrophobicContact CD1-CD2 3.83Å; I315-L361 HydrophobicContact CG1-CD2 4.25Å; L357-L361 HydrophobicContact CD1-CD1 3.91Å; L357-L361 HydrophobicContact CD1-CG 4.08Å; L357-L361 HydrophobicContact CG-CD1 3.9Å; L357-L361 HydrophobicContact CG-CG 4.47Å; L357-L361 WeakPolarHBondContact O-CB 3.39Å; L357-L361 VanDerWaalsContact O-CG 3.29Å; L357-L361 WeakPolarHBondContact O-CG 3.44Å; L357-L361 PolarHBondContact O-N 3.23Å; Y359-L361 PolarHBondContact O-N 3.45Å; L361-R363 PolarHBondContact O-N 3.29Å; L361-K371 PolarHBondContact O-NZ 2.74Å
362G97Very high97.3Very high28 Ų2835 Ų3529%0.28921%0.209SC..Hα-helixtrans-65.6-17.2174.500000114.8G237 A358 Y359 V360 A364G237-G362 WeakPolarHBondContact O-CA 3.04Å; A358-G362 PolarHBondContact O-N 2.84Å; Y359-G362 PolarHBondContact O-N 3.13Å; V360-G362 VanDerWaalsContact C-N 3.29Å; V360-G362 PolarHBondContact O-N 2.87Å; G362-A364 PolarHBondContact O-N 2.8Å
363R96.2Very high97.1Very high33 Ų3337.1 Ų37.113%0.12523%0.226CC..  trans-72.284.8172.8-66-69.5-63.2-89.2-7.8111.3E135 R235 Y359 V360 L361 D365 L366 K371E135-R363 IonicContact OE1-NH1 3.84Å; R235-R363 VanDerWaalsContact NE-CD 3.3Å; Y359-R363 PolarHBondContact O-N 3.32Å; Y359-R363 PolarHBondContact OH-NH1 2.95Å; V360-R363 WeakPolarHBondContact O-CB 3.44Å; V360-R363 PolarHBondContact O-N 3.48Å; L361-R363 PolarHBondContact O-N 3.29Å; R363-D365 WeakPolarHBondContact CA-OD1 3.25Å; R363-D365 WeakPolarHBondContact CB-OD1 3.43Å; R363-D365 IonicContact CZ-OD1 3.82Å; R363-D365 IonicContact CZ-OD2 2.86Å; R363-D365 IonicContact NE-OD1 3.78Å; R363-D365 PolarHBondContact NE-OD1 2.65Å; R363-D365 IonicContact NE-OD2 2.98Å; R363-D365 PolarHBondContact NE-OD2 3.32Å; R363-D365 VanDerWaalsContact NE-OD2 3.13Å; R363-D365 IonicContact NH2-OD1 3.48Å; R363-D365 IonicContact NH2-OD2 2.62Å; R363-D365 PolarHBondContact NH2-OD2 2.98Å; R363-D365 PolarHBondContact O-N 2.66Å; R363-L366 HydrophobicContact CB-CB 4.19Å; R363-L366 HydrophobicContact CB-CD1 3.63Å; R363-L366 HydrophobicContact CB-CG 3.81Å; R363-L366 HydrophobicContact CG-CD1 3.9Å; R363-L366 HydrophobicContact CG-CG 4.49Å; R363-L366 PolarHBondContact O-N 2.69Å; R363-K371 WeakPolarHBondContact O-CE 3.2Å; R363-K371 PolarHBondContact O-NZ 2.82Å
364A94Very high96.9Very high101 Ų10138.2 Ų38.284%0.83523%0.232SC*.THydrogen-bonded Turntrans-63.7-21.9176.600000113G362 L366G362-A364 PolarHBondContact O-N 2.8Å; A364-L366 VanDerWaalsContact C-N 3.28Å; A364-L366 PolarHBondContact O-N 3.32Å
365D95.5Very high96.8Very high98 Ų9837.4 Ų37.452%0.52423%0.227SC..THydrogen-bonded Turntrans-76.5-8.1178.459.6-56.5000114.3R363R363-D365 WeakPolarHBondContact CA-OD1 3.25Å; R363-D365 WeakPolarHBondContact CB-OD1 3.43Å; R363-D365 IonicContact CZ-OD1 3.82Å; R363-D365 IonicContact CZ-OD2 2.86Å; R363-D365 IonicContact NE-OD1 3.78Å; R363-D365 PolarHBondContact NE-OD1 2.65Å; R363-D365 IonicContact NE-OD2 2.98Å; R363-D365 PolarHBondContact NE-OD2 3.32Å; R363-D365 VanDerWaalsContact NE-OD2 3.13Å; R363-D365 IonicContact NH2-OD1 3.48Å; R363-D365 IonicContact NH2-OD2 2.62Å; R363-D365 PolarHBondContact NH2-OD2 2.98Å; R363-D365 PolarHBondContact O-N 2.66Å
366L96.5Very high96.5Very high31 Ų3139.8 Ų39.816%0.16224%0.244CC..SBendtrans-108.4137.9-177.6-61.3-179000112R363 A364 E370 K371 L374R363-L366 HydrophobicContact CB-CB 4.19Å; R363-L366 HydrophobicContact CB-CD1 3.63Å; R363-L366 HydrophobicContact CB-CG 3.81Å; R363-L366 HydrophobicContact CG-CD1 3.9Å; R363-L366 HydrophobicContact CG-CG 4.49Å; R363-L366 PolarHBondContact O-N 2.69Å; A364-L366 VanDerWaalsContact C-N 3.28Å; A364-L366 PolarHBondContact O-N 3.32Å; L366-E370 HydrophobicContact CB-CB 4.07Å; L366-E370 HydrophobicContact CD2-CB 4.16Å; L366-K371 HydrophobicContact CB-CG 3.86Å; L366-K371 VanDerWaalsContact O-CE 3.29Å; L366-K371 WeakPolarHBondContact O-CE 3.31Å; L366-L374 HydrophobicContact CD1-CD2 3.63Å
367S97.3Very high96.1Very high58 Ų5844.7 Ų44.741%0.40627%0.267SS..  trans-65.2163167.268.80000111.7C369 E370 K371S367-C369 PolarHBondContact O-N 3.47Å; S367-E370 WeakPolarHBondContact CB-OE2 3.42Å; S367-E370 PolarHBondContact N-OE2 2.8Å; S367-E370 PolarHBondContact O-N 2.98Å; S367-E370 WeakPolarHBondContact OG-CG 3.06Å; S367-E370 PolarHBondContact OG-N 2.71Å; S367-E370 PolarHBondContact OG-OE2 3.17Å; S367-K371 WeakPolarHBondContact O-CG 3.23Å; S367-K371 PolarHBondContact O-N 3.12Å
368L96.6Very high95.9Very high74 Ų7447.7 Ų47.739%0.38728%0.283SS..Hα-helixtrans-57.8-37.1176-179.862000112.3G313 I315 K371 K372G313-L368 WeakPolarHBondContact O-CD1 3.37Å; I315-L368 HydrophobicContact CD1-CD1 3.99Å; I315-L368 HydrophobicContact CG1-CD1 3.8Å; L368-K371 PolarHBondContact O-N 3.18Å; L368-K372 HydrophobicContact CD1-CG 4.5Å; L368-K372 WeakPolarHBondContact O-CG 3.27Å; L368-K372 PolarHBondContact O-N 2.99Å
369C96.4Very high95.7Very high97 Ų9748.6 Ų48.666%0.65529%0.287SS*.Hα-helixtrans-64.9-47177.9-169.90000111.2S367 K371 K372 A373S367-C369 PolarHBondContact O-N 3.47Å; C369-K371 VanDerWaalsContact C-N 3.34Å; C369-K371 PolarHBondContact O-N 3.2Å; C369-K372 PolarHBondContact O-N 3.09Å; C369-A373 PolarHBondContact O-N 3.39Å
370E97.6Very high95.5Very high96 Ų9650.1 Ų50.145%0.44929%0.293SS..Hα-helixtrans-63.6-39.3176.9-70163129.300111.8L366 S367 A373 L374L366-E370 HydrophobicContact CB-CB 4.07Å; L366-E370 HydrophobicContact CD2-CB 4.16Å; S367-E370 WeakPolarHBondContact CB-OE2 3.42Å; S367-E370 PolarHBondContact N-OE2 2.8Å; S367-E370 PolarHBondContact O-N 2.98Å; S367-E370 WeakPolarHBondContact OG-CG 3.06Å; S367-E370 PolarHBondContact OG-N 2.71Å; S367-E370 PolarHBondContact OG-OE2 3.17Å; E370-A373 PolarHBondContact O-N 3.27Å; E370-L374 VanDerWaalsContact O-CB 3.3Å; E370-L374 WeakPolarHBondContact O-CB 3.3Å; E370-L374 PolarHBondContact O-N 3.1Å
371K98Very high95.3Very high25 Ų2550.1 Ų50.111%0.10929%0.293CS..Hα-helixtrans-59.9-47173.2-72.9-178.8-179.7-175.50111.9I315 V360 L361 R363 L366 S367 L368 C369 A373 L374 M375I315-K371 HydrophobicContact CD1-CB 3.69Å; V360-K371 HydrophobicContact CG1-CB 3.54Å; V360-K371 HydrophobicContact CG1-CD 4.49Å; V360-K371 HydrophobicContact CG1-CG 3.77Å; V360-K371 WeakPolarHBondContact CG1-O 3.46Å; V360-K371 WeakPolarHBondContact O-CE 3.4Å; L361-K371 PolarHBondContact O-NZ 2.74Å; R363-K371 WeakPolarHBondContact O-CE 3.2Å; R363-K371 PolarHBondContact O-NZ 2.82Å; L366-K371 HydrophobicContact CB-CG 3.86Å; L366-K371 VanDerWaalsContact O-CE 3.29Å; L366-K371 WeakPolarHBondContact O-CE 3.31Å; S367-K371 WeakPolarHBondContact O-CG 3.23Å; S367-K371 PolarHBondContact O-N 3.12Å; L368-K371 PolarHBondContact O-N 3.18Å; C369-K371 VanDerWaalsContact C-N 3.34Å; C369-K371 PolarHBondContact O-N 3.2Å; K371-A373 VanDerWaalsContact C-N 3.34Å; K371-A373 PolarHBondContact O-N 3.09Å; K371-L374 PolarHBondContact O-N 3.46Å; K371-M375 PolarHBondContact O-N 2.85Å
372K96.2Very high95.3Very high55 Ų5549.6 Ų49.624%0.23929%0.291CS..Hα-helixtrans-61.6-42.2176.6-72.6-177.5177.9-170.90111.7I315 L343 L368 C369 M375 S376I315-K372 HydrophobicContact CD1-CG 4.42Å; I315-K372 HydrophobicContact CG1-CG 4.4Å; L343-K372 HydrophobicContact CD1-CB 4.09Å; L343-K372 HydrophobicContact CD1-CG 4.13Å; L343-K372 HydrophobicContact CD2-CB 4.19Å; L343-K372 HydrophobicContact CD2-CG 4.38Å; L368-K372 HydrophobicContact CD1-CG 4.5Å; L368-K372 WeakPolarHBondContact O-CG 3.27Å; L368-K372 PolarHBondContact O-N 2.99Å; C369-K372 PolarHBondContact O-N 3.09Å; K372-M375 PolarHBondContact O-N 2.65Å; K372-S376 PolarHBondContact O-OG 2.73Å
373A94Very high95.1Very high43 Ų4348.5 Ų48.536%0.35528%0.278SS..Hα-helixtrans-62.4-43.9175.600000111.9C369 E370 K371 M375 S376 Q377C369-A373 PolarHBondContact O-N 3.39Å; E370-A373 PolarHBondContact O-N 3.27Å; K371-A373 VanDerWaalsContact C-N 3.34Å; K371-A373 PolarHBondContact O-N 3.09Å; A373-M375 VanDerWaalsContact C-N 3.34Å; A373-M375 PolarHBondContact O-N 3.36Å; A373-S376 PolarHBondContact O-N 2.98Å; A373-S376 VanDerWaalsContact O-N 3.11Å; A373-Q377 WeakPolarHBondContact O-CG 3.45Å; A373-Q377 PolarHBondContact O-N 2.83Å
374L95Very high94.7Very high24 Ų2450.1 Ų50.113%0.12629%0.292CS..Hα-helixtrans-64.6-36-179.3-166.863.1000112.6K356 Y359 V360 L366 E370 K371 S376 Q377 I379K356-L374 VanDerWaalsContact CE-O 3.26Å; K356-L374 WeakPolarHBondContact CE-O 3.48Å; K356-L374 PolarHBondContact NZ-O 3.38Å; Y359-L374 HydrophobicContact CE1-CD2 4.11Å; V360-L374 HydrophobicContact CG1-CB 4.5Å; V360-L374 HydrophobicContact CG2-CB 4.26Å; V360-L374 HydrophobicContact CG2-CD2 3.86Å; V360-L374 HydrophobicContact CG2-CG 3.97Å; L366-L374 HydrophobicContact CD1-CD2 3.63Å; E370-L374 VanDerWaalsContact O-CB 3.3Å; E370-L374 WeakPolarHBondContact O-CB 3.3Å; E370-L374 PolarHBondContact O-N 3.1Å; K371-L374 PolarHBondContact O-N 3.46Å; L374-S376 VanDerWaalsContact C-N 3.25Å; L374-S376 PolarHBondContact O-N 2.8Å; L374-Q377 PolarHBondContact O-N 2.85Å; L374-I379 HydrophobicContact CD1-CG2 3.65Å; L374-I379 HydrophobicContact CG-CG2 4.48Å
375M95.7Very high93.7Very high2 Ų248.9 Ų48.91%0.0127%0.274CS..Hα-helixtrans-59.8-35.3173-79.7-54-49.500112.8I315 V317 L343 K356 L357 V360 K371 K372 A373I315-M375 HydrophobicContact CG2-CG 4.28Å; V317-M375 HydrophobicContact CG1-CE 4.33Å; V317-M375 HydrophobicContact CG2-CE 3.75Å; L343-M375 HydrophobicContact CD1-CB 3.69Å; L343-M375 HydrophobicContact CD1-CG 4.19Å; K356-M375 HydrophobicContact CB-CE 4.15Å; K356-M375 HydrophobicContact CB-SD 4.34Å; K356-M375 HydrophobicContact CD-CE 3.89Å; K356-M375 HydrophobicContact CD-SD 4.22Å; K356-M375 WeakPolarHBondContact CE-O 3.43Å; K356-M375 HydrophobicContact CG-CE 3.96Å; K356-M375 HydrophobicContact CG-SD 3.82Å; K356-M375 PolarHBondContact NZ-O 3.25Å; L357-M375 HydrophobicContact CB-CE 4.46Å; L357-M375 HydrophobicContact CB-SD 4.32Å; L357-M375 HydrophobicContact CD1-SD 4.17Å; V360-M375 HydrophobicContact CB-CG 4.33Å; V360-M375 HydrophobicContact CB-SD 3.9Å; V360-M375 HydrophobicContact CG1-CG 4.11Å; V360-M375 HydrophobicContact CG1-SD 4.35Å; V360-M375 HydrophobicContact CG2-CG 4.2Å; V360-M375 HydrophobicContact CG2-SD 3.6Å; V360-M375 VanDerWaalsContact CG2-SD 3.6Å; K371-M375 PolarHBondContact O-N 2.85Å; K372-M375 PolarHBondContact O-N 2.65Å; A373-M375 VanDerWaalsContact C-N 3.34Å; A373-M375 PolarHBondContact O-N 3.36Å
376S90.9Very high91.8Very high53 Ų5348.2 Ų48.237%0.37128%0.282SS..Hα-helixtrans-87.3-8.3-177.7-57.50000114.4K372 A373 L374K372-S376 PolarHBondContact O-OG 2.73Å; A373-S376 PolarHBondContact O-N 2.98Å; A373-S376 VanDerWaalsContact O-N 3.11Å; L374-S376 VanDerWaalsContact C-N 3.25Å; L374-S376 PolarHBondContact O-N 2.8Å
377Q91.4Very high89.1Confident103 Ų10354.5 Ų54.548%0.48131%0.312SS..SBendtrans-94.2145.1179.9-73.117311.200111.7K356 A373 L374 I379K356-Q377 PolarHBondContact NZ-O 3.16Å; A373-Q377 WeakPolarHBondContact O-CG 3.45Å; A373-Q377 PolarHBondContact O-N 2.83Å; L374-Q377 PolarHBondContact O-N 2.85Å; Q377-I379 HydrophobicContact CB-CG2 4.16Å; Q377-I379 PolarHBondContact O-N 3.24Å
378N93Very high85.8Confident62 Ų6259.6 Ų59.633%0.33233%0.33SS..  trans-73.5111.1167.117711.5000109.9G381 E382 L383 V385N378-G381 WeakPolarHBondContact OD1-CA 3.49Å; N378-G381 PolarHBondContact OD1-N 2.64Å; N378-E382 PolarHBondContact OD1-OE2 2.96Å; N378-L383 HydrophobicContact CB-CD2 4.44Å; N378-L383 VanDerWaalsContact CB-O 3.32Å; N378-L383 WeakPolarHBondContact CB-O 3.35Å; N378-L383 PolarHBondContact ND2-O 3.19Å; N378-V385 HydrophobicContact CB-CG2 3.98Å
379I93.8Very high82.6Confident19 Ų1960.4 Ų60.410%0.09734%0.341CS..SBendtrans-111.2-20.6-174.958.8170.3000114.2F132 F224 K356 Y359 L374 Q377 E382F132-I379 HydrophobicContact CD1-CD1 3.65Å; F132-I379 HydrophobicContact CD1-CG1 4.07Å; F132-I379 HydrophobicContact CE1-CD1 3.75Å; F132-I379 HydrophobicContact CE1-CG1 3.78Å; F224-I379 WeakPolarHBondContact CZ-O 3.08Å; K356-I379 HydrophobicContact CG-CD1 4.32Å; Y359-I379 HydrophobicContact CD1-CD1 4.21Å; Y359-I379 HydrophobicContact CE1-CD1 3.82Å; L374-I379 HydrophobicContact CD1-CG2 3.65Å; L374-I379 HydrophobicContact CG-CG2 4.48Å; Q377-I379 HydrophobicContact CB-CG2 4.16Å; Q377-I379 PolarHBondContact O-N 3.24Å; I379-E382 WeakPolarHBondContact CG1-OE1 3.17Å; I379-E382 PolarHBondContact N-OE1 3.45Å; I379-E382 PolarHBondContact N-OE2 2.81Å
380R95.1Very high79.5Confident40 Ų4063.4 Ų63.415%0.15135%0.345CS..SBendtrans-143.117.6-176.6-64.7-64.7-177-80.3-8.4112.7S131 F132 F134 E135 N188 E382S131-R380 VanDerWaalsContact O-CD 3.23Å; S131-R380 WeakPolarHBondContact O-CD 3.03Å; S131-R380 WeakPolarHBondContact O-CG 2.84Å; S131-R380 PolarHBondContact O-NE 3.27Å; F132-R380 HydrophobicContact CD1-CB 4.37Å; F132-R380 HydrophobicContact CD1-CG 3.8Å; F132-R380 HydrophobicContact CE1-CB 4.15Å; F132-R380 HydrophobicContact CE1-CG 4.06Å; F134-R380 PolarHBondContact O-NE 3.26Å; F134-R380 VanDerWaalsContact O-NE 3.12Å; E135-R380 VanDerWaalsContact CA-NH2 3.34Å; E135-R380 VanDerWaalsContact CG-NH2 3.31Å; E135-R380 IonicContact OE1-NH2 3.36Å; N188-R380 VanDerWaalsContact ND2-CB 3.32Å; N188-R380 WeakPolarHBondContact ND2-CB 3.35Å; N188-R380 PolarHBondContact ND2-O 2.62Å; R380-E382 VanDerWaalsContact C-N 3.34Å; R380-E382 WeakPolarHBondContact CA-OE2 3.4Å; R380-E382 PolarHBondContact N-OE2 3.39Å
381G94.2Very high76.6Confident0 Ų065.8 Ų65.80%036%0.36CS..SBendtrans83.86.7-177.500000114.5R186 R189 N378R186-G381 WeakPolarHBondContact CD-O 3.38Å; R186-G381 PolarHBondContact NH1-O 3.01Å; R189-G381 PolarHBondContact NE-O 3.3Å; R189-G381 PolarHBondContact NH2-O 2.93Å; N378-G381 WeakPolarHBondContact OD1-CA 3.49Å; N378-G381 PolarHBondContact OD1-N 2.64Å
382E96.5Very high73.9Confident0 Ų067 Ų670%038%0.379CS..  trans-76.9-22.9-172.878.4-72.8175.600114.3F132 N188 R189 L348 A352 K356 N378 I379 R380F132-E382 HydrophobicContact CE1-CG 4.12Å; F132-E382 HydrophobicContact CZ-CB 4.06Å; F132-E382 HydrophobicContact CZ-CG 3.83Å; N188-E382 HydrophobicContact CB-CB 4.04Å; N188-E382 WeakPolarHBondContact OD1-CA 3.26Å; R189-E382 WeakPolarHBondContact CD-O 3.33Å; R189-E382 PolarHBondContact NE-O 3.42Å; R189-E382 PolarHBondContact NH1-O 3.13Å; L348-E382 HydrophobicContact CD2-CB 3.96Å; L348-E382 HydrophobicContact CD2-CG 3.4Å; A352-E382 HydrophobicContact CB-CB 4.42Å; K356-E382 HydrophobicContact CD-CG 4.26Å; K356-E382 VanDerWaalsContact CE-OE1 3.3Å; K356-E382 WeakPolarHBondContact CE-OE1 3.23Å; K356-E382 IonicContact NZ-OE1 3.38Å; K356-E382 PolarHBondContact NZ-OE1 2.88Å; N378-E382 PolarHBondContact OD1-OE2 2.96Å; I379-E382 WeakPolarHBondContact CG1-OE1 3.17Å; I379-E382 PolarHBondContact N-OE1 3.45Å; I379-E382 PolarHBondContact N-OE2 2.81Å; R380-E382 VanDerWaalsContact C-N 3.34Å; R380-E382 WeakPolarHBondContact CA-OE2 3.4Å; R380-E382 PolarHBondContact N-OE2 3.39Å
383L93Very high71.4Confident4 Ų474 Ų742%0.02140%0.404CS..  trans-133139.8-172.4174.9148.1000110.4L348 N378 V385L348-L383 HydrophobicContact CD1-CD1 4.22Å; L348-L383 HydrophobicContact CD2-CB 4.21Å; L348-L383 HydrophobicContact CG-CB 4.33Å; L348-L383 HydrophobicContact CG-CD1 4.09Å; N378-L383 HydrophobicContact CB-CD2 4.44Å; N378-L383 VanDerWaalsContact CB-O 3.32Å; N378-L383 WeakPolarHBondContact CB-O 3.35Å; N378-L383 PolarHBondContact ND2-O 3.19Å; L383-V385 HydrophobicContact CD2-CB 4.45Å; L383-V385 HydrophobicContact CD2-CG2 3.61Å
384T88.7Confident69.2Low68 Ų6874.3 Ų74.342%0.41740%0.4SS..  trans-93.5114.6171.5-49.10000108.4R189 S346 D347R189-T384 PolarHBondContact NH2-OG1 2.8Å; S346-T384 PolarHBondContact OG-O 3.47Å; D347-T384 PolarHBondContact OD1-N 3.12Å; D347-T384 VanDerWaalsContact OD2-CB 3.24Å; D347-T384 WeakPolarHBondContact OD2-CB 3.44Å; D347-T384 PolarHBondContact OD2-OG1 3.29Å
385V72.3Confident67.7Low75 Ų7579.6 Ų79.646%0.45542%0.423SS..  trans-78.1133.3174.5-177.10000107.7N378 L383 M387N378-V385 HydrophobicContact CB-CG2 3.98Å; L383-V385 HydrophobicContact CD2-CB 4.45Å; L383-V385 HydrophobicContact CD2-CG2 3.61Å; V385-M387 PolarHBondContact O-N 3.37Å
386A55.9Low66.4Low84 Ų8485.6 Ų85.669%0.69445%0.451SS*.SBendtrans-69.670.1174.200000110.8
387M39.5Very low65.8Low163 Ų16386.8 Ų86.880%0.80345%0.453SS*.SBendtrans-133.4125.3159.1-88.7-166.8146.600106.3V385 S389V385-M387 PolarHBondContact O-N 3.37Å; M387-S389 PolarHBondContact O-N 3.37Å
388E28.6Very low65.1Low165 Ų16582 Ų8277%0.77143%0.431SS*.  trans-47.9108.1175.1-68.7178.2161.900109.3H390E388-H390 VanDerWaalsContact C-N 3.35Å; E388-H390 PolarHBondContact O-N 3.48Å; E388-H390 IonicContact OE2-CE1 3.35Å
389S28.8Very low64.4Low90 Ų9082.2 Ų82.263%0.62944%0.435SS*.  trans-64.7103.3164.654.70000106.5M387 I391M387-S389 PolarHBondContact O-N 3.37Å; S389-I391 PolarHBondContact O-N 2.87Å
390H32.3Very low63.9Low161 Ų16187 Ų8775%0.74546%0.455SS*.  trans-65.341163.1-68.4-47.9000111.8E388 G392E388-H390 VanDerWaalsContact C-N 3.35Å; E388-H390 PolarHBondContact O-N 3.48Å; E388-H390 IonicContact OE2-CE1 3.35Å; H390-G392 PolarHBondContact O-N 2.84Å
391I36.4Very low63.4Low145 Ų14588.5 Ų88.574%0.74446%0.464SS*.THydrogen-bonded Turntrans-95.782.2174.3-55.9172.9000105.3S389S389-I391 PolarHBondContact O-N 2.87Å
392G40.2Very low63Low50 Ų5088.8 Ų88.852%0.51547%0.466SS..THydrogen-bonded Turntrans1776-176.100000116.2H390 D394H390-G392 PolarHBondContact O-N 2.84Å; G392-D394 PolarHBondContact O-N 3.5Å; G392-D394 VanDerWaalsContact O-N 3.14Å
393R43.5Very low62.5Low204 Ų20492 Ų9277%0.7749%0.493SS*.  trans-87.269.9166.5-73.3-168.6-173.8175.64.2110.8H395R393-H395 PolarHBondContact O-N 3.24Å
394D49.2Very low62.3Low49 Ų4997 Ų9726%0.26253%0.527SS..  trans-71.851.2161.8-80.3-39.2000111G392 T399 R417G392-D394 PolarHBondContact O-N 3.5Å; G392-D394 VanDerWaalsContact O-N 3.14Å; D394-T399 PolarHBondContact O-OG1 2.92Å; D394-R417 IonicContact OD1-CZ 2.7Å; D394-R417 IonicContact OD1-NE 3.34Å; D394-R417 IonicContact OD1-NH1 2.72Å; D394-R417 PolarHBondContact OD1-NH1 3.34Å; D394-R417 VanDerWaalsContact OD1-NH1 3.17Å; D394-R417 IonicContact OD1-NH2 3.79Å; D394-R417 IonicContact OD2-CZ 3.07Å; D394-R417 IonicContact OD2-NH1 3.79Å; D394-R417 PolarHBondContact OD2-NH1 3.07Å; D394-R417 IonicContact OD2-NH2 2.54Å; D394-R417 PolarHBondContact OD2-NH2 3.39Å
395H62.1Low62.4Low134 Ų13498.6 Ų98.662%0.6253%0.532SS*.  trans-114.8-16.6-151-88.4-50.4000121R393 T399R393-H395 PolarHBondContact O-N 3.24Å; H395-T399 WeakPolarHBondContact O-CB 3.35Å; H395-T399 PolarHBondContact O-OG1 3.46Å
396E69.5Low63.2Low128 Ų128101.6 Ų101.660%0.59855%0.546SS*.SBendtrans-120.8-58178.8-153.7172.2177.200114.8K400E396-K400 HydrophobicContact CG-CD 3.97Å; E396-K400 VanDerWaalsContact CG-CE 3.46Å; E396-K400 HydrophobicContact CG-CG 4.46Å; E396-K400 WeakPolarHBondContact O-CB 3.29Å; E396-K400 WeakPolarHBondContact O-CG 3.4Å; E396-K400 PolarHBondContact O-N 3.36Å; E396-K400 VanDerWaalsContact OE1-CE 3.25Å; E396-K400 WeakPolarHBondContact OE1-CE 3.43Å; E396-K400 IonicContact OE1-NZ 2.69Å; E396-K400 PolarHBondContact OE1-NZ 3.37Å
397L77.6Confident64.6Low78 Ų7899.6 Ų99.641%0.40852%0.524SS..Hα-helixtrans-66.1-53.3-174.4-175.264000112.4T399 K400 M401 M420 L424L397-T399 PolarHBondContact O-N 3.5Å; L397-K400 PolarHBondContact O-N 2.93Å; L397-M401 HydrophobicContact CD1-CE 3.98Å; L397-M401 HydrophobicContact CG-CE 4.48Å; L397-M401 WeakPolarHBondContact O-CB 3.48Å; L397-M401 WeakPolarHBondContact O-CG 3.33Å; L397-M401 PolarHBondContact O-N 3.11Å; L397-M420 HydrophobicContact CD2-CE 4.01Å; L397-M420 HydrophobicContact CD2-SD 3.87Å; L397-M420 HydrophobicContact CG-CE 4.3Å; L397-M420 HydrophobicContact CG-SD 4.03Å; L397-L424 HydrophobicContact CD2-CD1 3.86Å
398V77.9Confident66.6Low4 Ų497.6 Ų97.62%0.02452%0.521CS..Hα-helixtrans-62-45.1178.8177.10000110.3K400 M401 A402 L413 L416 R417 M420 Y421V398-K400 PolarHBondContact O-N 3.19Å; V398-M401 PolarHBondContact O-N 2.94Å; V398-A402 WeakPolarHBondContact O-CB 3.46Å; V398-A402 PolarHBondContact O-N 2.94Å; V398-L413 HydrophobicContact CG1-CD2 4.41Å; V398-L416 HydrophobicContact CG1-CD2 4.19Å; V398-R417 HydrophobicContact CG1-CG 4.05Å; V398-R417 HydrophobicContact CG2-CG 3.92Å; V398-M420 HydrophobicContact CG2-CE 3.67Å; V398-Y421 HydrophobicContact CG2-CE2 4.1Å; V398-Y421 VanDerWaalsContact CG2-OH 3.23Å; V398-Y421 WeakPolarHBondContact CG2-OH 3.25Å
399T77Confident69.2Low65 Ų6592.8 Ų92.840%0.39950%0.503SS..Hα-helixtrans-60.1-45.9178.5-43.80000111.8D394 H395 L397 A402 A403D394-T399 PolarHBondContact O-OG1 2.92Å; H395-T399 WeakPolarHBondContact O-CB 3.35Å; H395-T399 PolarHBondContact O-OG1 3.46Å; L397-T399 PolarHBondContact O-N 3.5Å; T399-A402 PolarHBondContact O-N 3.35Å; T399-A403 WeakPolarHBondContact O-CB 3.4Å; T399-A403 PolarHBondContact O-N 2.96Å
400K83.8Confident71.5Confident121 Ų12194.5 Ų94.553%0.52651%0.51SS..Hα-helixtrans-65.3-44.5178.2-76.1180-179.2177.10111.5E396 L397 V398 A403 C404E396-K400 HydrophobicContact CG-CD 3.97Å; E396-K400 VanDerWaalsContact CG-CE 3.46Å; E396-K400 HydrophobicContact CG-CG 4.46Å; E396-K400 WeakPolarHBondContact O-CB 3.29Å; E396-K400 WeakPolarHBondContact O-CG 3.4Å; E396-K400 PolarHBondContact O-N 3.36Å; E396-K400 VanDerWaalsContact OE1-CE 3.25Å; E396-K400 WeakPolarHBondContact OE1-CE 3.43Å; E396-K400 IonicContact OE1-NZ 2.69Å; E396-K400 PolarHBondContact OE1-NZ 3.37Å; L397-K400 PolarHBondContact O-N 2.93Å; V398-K400 PolarHBondContact O-N 3.19Å; K400-A403 PolarHBondContact O-N 2.94Å; K400-C404 PolarHBondContact O-N 3.02Å; K400-C404 PolarHBondContact O-SG 3.26Å
401M84.7Confident73.6Confident71 Ų7193.8 Ų93.835%0.3551%0.507SS..Hα-helixtrans-65.9-41.8177.3-75.8-164.8178.100112.4L397 V398 A403 C404 L405 L416 M420L397-M401 HydrophobicContact CD1-CE 3.98Å; L397-M401 HydrophobicContact CG-CE 4.48Å; L397-M401 WeakPolarHBondContact O-CB 3.48Å; L397-M401 WeakPolarHBondContact O-CG 3.33Å; L397-M401 PolarHBondContact O-N 3.11Å; V398-M401 PolarHBondContact O-N 2.94Å; M401-A403 VanDerWaalsContact C-N 3.31Å; M401-A403 PolarHBondContact O-N 3.25Å; M401-C404 PolarHBondContact O-N 3.48Å; M401-L405 WeakPolarHBondContact O-CB 3.33Å; M401-L405 WeakPolarHBondContact O-CG 3.13Å; M401-L405 PolarHBondContact O-N 3.2Å; M401-L416 HydrophobicContact CB-CD2 3.9Å; M401-M420 HydrophobicContact CE-SD 3.81Å; M401-M420 HydrophobicContact SD-CG 4.24Å; M401-M420 HydrophobicContact SD-SD 3.24Å
402A85.3Confident75.9Confident5 Ų590.1 Ų90.14%0.04149%0.486CS..Hα-helixtrans-60.5-42.6175.100000111.4V398 T399 L405 N406 L407 L413 L416V398-A402 WeakPolarHBondContact O-CB 3.46Å; V398-A402 PolarHBondContact O-N 2.94Å; T399-A402 PolarHBondContact O-N 3.35Å; A402-L405 CarbonylContact O-C 3.47Å; A402-L405 PolarHBondContact O-N 2.67Å; A402-N406 PolarHBondContact O-N 2.96Å; A402-L407 HydrophobicContact CB-CB 4.18Å; A402-L407 PolarHBondContact O-N 2.63Å; A402-L413 HydrophobicContact CB-CD2 3.26Å; A402-L416 HydrophobicContact CB-CD2 4.2Å
403A86.7Confident77.9Confident68 Ų6889.8 Ų89.856%0.56247%0.472SS*.Hα-helixtrans-61.8-43.1173.700000112T399 K400 M401 L405 N406T399-A403 WeakPolarHBondContact O-CB 3.4Å; T399-A403 PolarHBondContact O-N 2.96Å; K400-A403 PolarHBondContact O-N 2.94Å; M401-A403 VanDerWaalsContact C-N 3.31Å; M401-A403 PolarHBondContact O-N 3.25Å; A403-L405 VanDerWaalsContact C-N 3.28Å; A403-L405 PolarHBondContact O-N 2.9Å; A403-N406 PolarHBondContact O-N 3.08Å
404C88.9Confident79.5Confident108 Ų10885.8 Ų85.873%0.7346%0.457SS*.Hα-helixtrans-64.5-31.1175.9-68.90000113.4K400 M401K400-C404 PolarHBondContact O-N 3.02Å; K400-C404 PolarHBondContact O-SG 3.26Å; M401-C404 PolarHBondContact O-N 3.48Å
405L89.7Confident81.1Confident102 Ų10287.5 Ų87.553%0.53447%0.466SS..THydrogen-bonded Turntrans-96.83.4-178.3-66.1174000113.2M401 A402 A403 L407 L416M401-L405 WeakPolarHBondContact O-CB 3.33Å; M401-L405 WeakPolarHBondContact O-CG 3.13Å; M401-L405 PolarHBondContact O-N 3.2Å; A402-L405 CarbonylContact O-C 3.47Å; A402-L405 PolarHBondContact O-N 2.67Å; A403-L405 VanDerWaalsContact C-N 3.28Å; A403-L405 PolarHBondContact O-N 2.9Å; L405-L407 HydrophobicContact CB-CD1 3.93Å; L405-L407 HydrophobicContact CB-CD2 4.32Å; L405-L407 HydrophobicContact CB-CG 3.67Å; L405-L407 HydrophobicContact CD1-CD1 4.02Å; L405-L407 PolarHBondContact O-N 3.34Å; L405-L416 HydrophobicContact CD1-CD1 3.83Å
406N89.4Confident82.3Confident139 Ų13982.1 Ų82.174%0.74344%0.442SS*.THydrogen-bonded Turntrans51.635.4-173.7-63.8-49.7000113.8A402 A403A402-N406 PolarHBondContact O-N 2.96Å; A403-N406 PolarHBondContact O-N 3.08Å
407L86.5Confident82.8Confident42 Ų4279.6 Ų79.622%0.2243%0.427CS..  trans-84.3126.5177.7-57.7179.4000109.5A402 L405 E412 L416A402-L407 HydrophobicContact CB-CB 4.18Å; A402-L407 PolarHBondContact O-N 2.63Å; L405-L407 HydrophobicContact CB-CD1 3.93Å; L405-L407 HydrophobicContact CB-CD2 4.32Å; L405-L407 HydrophobicContact CB-CG 3.67Å; L405-L407 HydrophobicContact CD1-CD1 4.02Å; L405-L407 PolarHBondContact O-N 3.34Å; L407-E412 HydrophobicContact CB-CB 3.89Å; L407-E412 HydrophobicContact CD1-CB 4.34Å; L407-E412 HydrophobicContact CD2-CB 3.94Å; L407-E412 HydrophobicContact CD2-CG 3.97Å; L407-E412 HydrophobicContact CG-CB 4.23Å; L407-L416 HydrophobicContact CD1-CB 4.13Å; L407-L416 HydrophobicContact CD1-CD1 4.43Å; L407-L416 HydrophobicContact CD1-CD2 4.15Å; L407-L416 HydrophobicContact CD1-CG 4.47Å
408T80.5Confident82.8Confident121 Ų12180.5 Ų80.574%0.74243%0.429SS*.  trans-126.1-23-171.857.10000112.9E412T408-E412 PolarHBondContact N-OE2 3.15Å
409T82.9Confident83.1Confident64 Ų6486.2 Ų86.239%0.39346%0.459SS..SBendtrans-87.3150.4-17769.80000111.6Q411 E412 L413T409-Q411 PolarHBondContact O-N 3.39Å; T409-E412 WeakPolarHBondContact CB-OE2 3.37Å; T409-E412 PolarHBondContact N-OE2 2.57Å; T409-E412 PolarHBondContact O-N 2.61Å; T409-E412 WeakPolarHBondContact OG1-CB 3.12Å; T409-E412 WeakPolarHBondContact OG1-CG 3.47Å; T409-E412 PolarHBondContact OG1-N 2.88Å; T409-E412 VanDerWaalsContact OG1-N 3.12Å; T409-E412 PolarHBondContact OG1-OE2 2.94Å; T409-L413 WeakPolarHBondContact O-CG 3.43Å; T409-L413 PolarHBondContact O-N 2.66Å
410T78.7Confident83.6Confident126 Ų12683.8 Ų83.877%0.77344%0.443SS*.Hα-helixtrans-58.5-32.9175-47.80000112.1R414T410-R414 VanDerWaalsContact O-CB 3.3Å; T410-R414 WeakPolarHBondContact O-CB 3.34Å; T410-R414 PolarHBondContact O-N 2.99Å
411Q76.2Confident83.7Confident146 Ų14678.8 Ų78.868%0.68242%0.421SS*.Hα-helixtrans-69.5-44.4177.8-174.6171.5-2.100111.7T409 R414 L415T409-Q411 PolarHBondContact O-N 3.39Å; Q411-R414 PolarHBondContact O-N 2.6Å; Q411-L415 HydrophobicContact CG-CD1 4.28Å; Q411-L415 WeakPolarHBondContact O-CG 3.36Å; Q411-L415 PolarHBondContact O-N 2.88Å
412E84Confident83.8Confident67 Ų6776.4 Ų76.431%0.31341%0.411SS..Hα-helixtrans-62.2-44.6175.1-73.5163155.700111.8L407 T408 T409 R414 L415 L416L407-E412 HydrophobicContact CB-CB 3.89Å; L407-E412 HydrophobicContact CD1-CB 4.34Å; L407-E412 HydrophobicContact CD2-CB 3.94Å; L407-E412 HydrophobicContact CD2-CG 3.97Å; L407-E412 HydrophobicContact CG-CB 4.23Å; T408-E412 PolarHBondContact N-OE2 3.15Å; T409-E412 WeakPolarHBondContact CB-OE2 3.37Å; T409-E412 PolarHBondContact N-OE2 2.57Å; T409-E412 PolarHBondContact O-N 2.61Å; T409-E412 WeakPolarHBondContact OG1-CB 3.12Å; T409-E412 WeakPolarHBondContact OG1-CG 3.47Å; T409-E412 PolarHBondContact OG1-N 2.88Å; T409-E412 VanDerWaalsContact OG1-N 3.12Å; T409-E412 PolarHBondContact OG1-OE2 2.94Å; E412-R414 VanDerWaalsContact C-N 3.27Å; E412-R414 PolarHBondContact O-N 2.92Å; E412-L415 PolarHBondContact O-N 2.84Å; E412-L416 WeakPolarHBondContact O-CB 3.42Å; E412-L416 PolarHBondContact O-N 3.5Å
413L81.1Confident84Confident44 Ų4482.5 Ų82.523%0.2344%0.44CS..Hα-helixtrans-60.8-39.2176.4-69.1177.9000111.7V398 A402 T409 R417V398-L413 HydrophobicContact CG1-CD2 4.41Å; A402-L413 HydrophobicContact CB-CD2 3.26Å; T409-L413 WeakPolarHBondContact O-CG 3.43Å; T409-L413 PolarHBondContact O-N 2.66Å; L413-R417 VanDerWaalsContact O-CG 3.26Å; L413-R417 WeakPolarHBondContact O-CG 3.22Å; L413-R417 PolarHBondContact O-N 3.13Å; L413-R417 VanDerWaalsContact O-N 3.16Å
414R78.3Confident84.2Confident119 Ų11982 Ų8245%0.44943%0.427SS..Hα-helixtrans-65.7-48.4175.9-179.4178.5172.9175.5-2111.6T410 Q411 E412 L416 R417 E418T410-R414 VanDerWaalsContact O-CB 3.3Å; T410-R414 WeakPolarHBondContact O-CB 3.34Å; T410-R414 PolarHBondContact O-N 2.99Å; Q411-R414 PolarHBondContact O-N 2.6Å; E412-R414 VanDerWaalsContact C-N 3.27Å; E412-R414 PolarHBondContact O-N 2.92Å; R414-L416 VanDerWaalsContact C-N 3.29Å; R414-L416 PolarHBondContact O-N 2.93Å; R414-R417 WeakPolarHBondContact O-CB 3.37Å; R414-R417 PolarHBondContact O-N 3.03Å; R414-R417 VanDerWaalsContact O-N 3.13Å; R414-E418 HydrophobicContact CG-CG 4.41Å; R414-E418 IonicContact CZ-OE1 2.61Å; R414-E418 IonicContact NE-OE1 2.75Å; R414-E418 PolarHBondContact NE-OE1 2.99Å; R414-E418 IonicContact NH2-OE1 2.84Å; R414-E418 PolarHBondContact NH2-OE1 3.38Å; R414-E418 WeakPolarHBondContact O-CG 3.22Å; R414-E418 PolarHBondContact O-N 3.42Å
415L82.8Confident84.4Confident86 Ų8677 Ų7745%0.4539%0.393SS..Hα-helixtrans-59.3-41.2177.1-72.6170.3000111.5Q411 E412 R417 E418 L419Q411-L415 HydrophobicContact CG-CD1 4.28Å; Q411-L415 WeakPolarHBondContact O-CG 3.36Å; Q411-L415 PolarHBondContact O-N 2.88Å; E412-L415 PolarHBondContact O-N 2.84Å; L415-R417 VanDerWaalsContact C-N 3.33Å; L415-R417 PolarHBondContact O-N 2.75Å; L415-E418 PolarHBondContact O-N 3.15Å; L415-L419 WeakPolarHBondContact O-CB 2.9Å; L415-L419 WeakPolarHBondContact O-CG 3.38Å; L415-L419 PolarHBondContact O-N 3.32Å
416L86.5Confident84.5Confident21 Ų2176.8 Ų76.811%0.1139%0.386CS..Hα-helixtrans-57.5-46.1175.1-179.666.8000111.2V398 M401 A402 L405 L407 E412 R414 L419 M420V398-L416 HydrophobicContact CG1-CD2 4.19Å; M401-L416 HydrophobicContact CB-CD2 3.9Å; A402-L416 HydrophobicContact CB-CD2 4.2Å; L405-L416 HydrophobicContact CD1-CD1 3.83Å; L407-L416 HydrophobicContact CD1-CB 4.13Å; L407-L416 HydrophobicContact CD1-CD1 4.43Å; L407-L416 HydrophobicContact CD1-CD2 4.15Å; L407-L416 HydrophobicContact CD1-CG 4.47Å; E412-L416 WeakPolarHBondContact O-CB 3.42Å; E412-L416 PolarHBondContact O-N 3.5Å; R414-L416 VanDerWaalsContact C-N 3.29Å; R414-L416 PolarHBondContact O-N 2.93Å; L416-L419 PolarHBondContact O-N 3.25Å; L416-M420 WeakPolarHBondContact O-CB 3.21Å; L416-M420 PolarHBondContact O-N 2.74Å
417R80.7Confident84.6Confident74 Ų7474.6 Ų74.628%0.27937%0.371SS..Hα-helixtrans-64.1-45.6177.5-66.4171.1-161.3-167-2.4111.9D394 V398 L413 R414 L415 L419 M420 Y421D394-R417 IonicContact OD1-CZ 2.7Å; D394-R417 IonicContact OD1-NE 3.34Å; D394-R417 IonicContact OD1-NH1 2.72Å; D394-R417 PolarHBondContact OD1-NH1 3.34Å; D394-R417 VanDerWaalsContact OD1-NH1 3.17Å; D394-R417 IonicContact OD1-NH2 3.79Å; D394-R417 IonicContact OD2-CZ 3.07Å; D394-R417 IonicContact OD2-NH1 3.79Å; D394-R417 PolarHBondContact OD2-NH1 3.07Å; D394-R417 IonicContact OD2-NH2 2.54Å; D394-R417 PolarHBondContact OD2-NH2 3.39Å; V398-R417 HydrophobicContact CG1-CG 4.05Å; V398-R417 HydrophobicContact CG2-CG 3.92Å; L413-R417 VanDerWaalsContact O-CG 3.26Å; L413-R417 WeakPolarHBondContact O-CG 3.22Å; L413-R417 PolarHBondContact O-N 3.13Å; L413-R417 VanDerWaalsContact O-N 3.16Å; R414-R417 WeakPolarHBondContact O-CB 3.37Å; R414-R417 PolarHBondContact O-N 3.03Å; R414-R417 VanDerWaalsContact O-N 3.13Å; L415-R417 VanDerWaalsContact C-N 3.33Å; L415-R417 PolarHBondContact O-N 2.75Å; R417-L419 VanDerWaalsContact C-N 3.26Å; R417-L419 PolarHBondContact O-N 3.09Å; R417-M420 PolarHBondContact O-N 3.01Å; R417-Y421 HydrophobicContact CB-CD2 3.8Å; R417-Y421 HydrophobicContact CB-CE2 3.81Å; R417-Y421 HydrophobicContact CG-CD2 4.28Å; R417-Y421 HydrophobicContact CG-CE2 3.77Å; R417-Y421 WeakPolarHBondContact O-CD2 3.5Å; R417-Y421 PolarHBondContact O-N 2.8Å
418E78.1Confident85Confident98 Ų9872.6 Ų72.646%0.45836%0.361SS..Hα-helixtrans-64-29.4-179.3-73.7176.4177.500112.3R414 L415 P422R414-E418 HydrophobicContact CG-CG 4.41Å; R414-E418 IonicContact CZ-OE1 2.61Å; R414-E418 IonicContact NE-OE1 2.75Å; R414-E418 PolarHBondContact NE-OE1 2.99Å; R414-E418 IonicContact NH2-OE1 2.84Å; R414-E418 PolarHBondContact NH2-OE1 3.38Å; R414-E418 WeakPolarHBondContact O-CG 3.22Å; R414-E418 PolarHBondContact O-N 3.42Å; L415-E418 PolarHBondContact O-N 3.15Å; E418-P422 VanDerWaalsContact O-CD 3.22Å; E418-P422 WeakPolarHBondContact O-CD 3.22Å; E418-P422 WeakPolarHBondContact O-CG 3.33Å
419L83.8Confident85.7Confident124 Ų12466.8 Ų66.865%0.64933%0.326SS*.Hα-helixtrans-85.8-42.4174.6-68.4171000112.8L415 L416 R417L415-L419 WeakPolarHBondContact O-CB 2.9Å; L415-L419 WeakPolarHBondContact O-CG 3.38Å; L415-L419 PolarHBondContact O-N 3.32Å; L416-L419 PolarHBondContact O-N 3.25Å; R417-L419 VanDerWaalsContact C-N 3.26Å; R417-L419 PolarHBondContact O-N 3.09Å
420M86.6Confident86.2Confident14 Ų1466.1 Ų66.17%0.06932%0.323CS..Hα-helixtrans-76.1-51.2-170.9-179.2-169.361.700112.5L397 V398 M401 L416 R417 M423 L424L397-M420 HydrophobicContact CD2-CE 4.01Å; L397-M420 HydrophobicContact CD2-SD 3.87Å; L397-M420 HydrophobicContact CG-CE 4.3Å; L397-M420 HydrophobicContact CG-SD 4.03Å; V398-M420 HydrophobicContact CG2-CE 3.67Å; M401-M420 HydrophobicContact CE-SD 3.81Å; M401-M420 HydrophobicContact SD-CG 4.24Å; M401-M420 HydrophobicContact SD-SD 3.24Å; L416-M420 WeakPolarHBondContact O-CB 3.21Å; L416-M420 PolarHBondContact O-N 2.74Å; R417-M420 PolarHBondContact O-N 3.01Å; M420-M423 PolarHBondContact O-N 2.62Å; M420-L424 HydrophobicContact CG-CD1 3.65Å; M420-L424 HydrophobicContact CG-CG 4.17Å; M420-L424 WeakPolarHBondContact O-CG 3.37Å; M420-L424 PolarHBondContact O-N 2.86Å; M420-L424 VanDerWaalsContact O-N 3.08Å; M420-L424 HydrophobicContact SD-CD1 4.05Å
421Y86.4Confident86.9Confident16 Ų1665.4 Ų65.46%0.06331%0.311CS..Hα-helixtrans-63.8-43-171.2-74.1-60.9000113.4V398 R417 M423 L424 V425 G443 A445V398-Y421 HydrophobicContact CG2-CE2 4.1Å; V398-Y421 VanDerWaalsContact CG2-OH 3.23Å; V398-Y421 WeakPolarHBondContact CG2-OH 3.25Å; R417-Y421 HydrophobicContact CB-CD2 3.8Å; R417-Y421 HydrophobicContact CB-CE2 3.81Å; R417-Y421 HydrophobicContact CG-CD2 4.28Å; R417-Y421 HydrophobicContact CG-CE2 3.77Å; R417-Y421 WeakPolarHBondContact O-CD2 3.5Å; R417-Y421 PolarHBondContact O-N 2.8Å; Y421-M423 VanDerWaalsContact C-N 3.29Å; Y421-M423 PolarHBondContact O-N 2.54Å; Y421-L424 PolarHBondContact O-N 2.75Å; Y421-V425 WeakPolarHBondContact O-CB 3.34Å; Y421-V425 VanDerWaalsContact O-CG2 3.26Å; Y421-V425 WeakPolarHBondContact O-CG2 3.47Å; Y421-V425 PolarHBondContact O-N 3.1Å; Y421-G443 PolarHBondContact OH-O 3.21Å; Y421-A445 HydrophobicContact CD1-CB 3.36Å; Y421-A445 HydrophobicContact CE1-CB 3.78Å; Y421-A445 HydrophobicContact CG-CB 3.86Å
422P87.6Confident87.7Confident20 Ų2060 Ų6013%0.1329%0.294CS..Hα-helixtrans-58-41.3177.3-25.735.7000112.7E418 V425 Y426 C449E418-P422 VanDerWaalsContact O-CD 3.22Å; E418-P422 WeakPolarHBondContact O-CD 3.22Å; E418-P422 WeakPolarHBondContact O-CG 3.33Å; P422-V425 PolarHBondContact O-N 3.14Å; P422-Y426 VanDerWaalsContact O-CB 3.26Å; P422-Y426 WeakPolarHBondContact O-CB 3.36Å; P422-Y426 PolarHBondContact O-N 2.98Å; P422-C449 HydrophobicContact CG-CB 3.97Å
423M89.1Confident88.2Confident133 Ų13359.5 Ų59.566%0.65529%0.293SS*.Hα-helixtrans-65-43.2176.8-68.2-153.9-63.300112.5M420 Y421 Y426 Q427M420-M423 PolarHBondContact O-N 2.62Å; Y421-M423 VanDerWaalsContact C-N 3.29Å; Y421-M423 PolarHBondContact O-N 2.54Å; M423-Y426 PolarHBondContact O-N 3.5Å; M423-Q427 WeakPolarHBondContact O-CB 3.2Å; M423-Q427 PolarHBondContact O-N 3.01Å
424L91.3Very high88.9Confident57 Ų5759 Ų5930%0.29829%0.291SS..Hα-helixtrans-67.3-40178.3-67.5178.4000112.3L397 M420 Y421 Q427 A428 L440L397-L424 HydrophobicContact CD2-CD1 3.86Å; M420-L424 HydrophobicContact CG-CD1 3.65Å; M420-L424 HydrophobicContact CG-CG 4.17Å; M420-L424 WeakPolarHBondContact O-CG 3.37Å; M420-L424 PolarHBondContact O-N 2.86Å; M420-L424 VanDerWaalsContact O-N 3.08Å; M420-L424 HydrophobicContact SD-CD1 4.05Å; Y421-L424 PolarHBondContact O-N 2.75Å; L424-Q427 PolarHBondContact O-N 3.06Å; L424-A428 WeakPolarHBondContact O-CB 3.14Å; L424-A428 PolarHBondContact O-N 3.11Å; L424-L440 HydrophobicContact CB-CD1 3.81Å; L424-L440 HydrophobicContact CB-CD2 3.95Å; L424-L440 HydrophobicContact CD1-CD2 3.82Å
425V92.3Very high89.7Confident3 Ų363.8 Ų63.82%0.01831%0.309CS..Hα-helixtrans-63.4-47.1175.3167.80000110Y421 P422 Q427 A428 V429 L437 L440 A445 L447Y421-V425 WeakPolarHBondContact O-CB 3.34Å; Y421-V425 VanDerWaalsContact O-CG2 3.26Å; Y421-V425 WeakPolarHBondContact O-CG2 3.47Å; Y421-V425 PolarHBondContact O-N 3.1Å; P422-V425 PolarHBondContact O-N 3.14Å; V425-Q427 PolarHBondContact O-N 3.49Å; V425-A428 PolarHBondContact O-N 3.41Å; V425-V429 WeakPolarHBondContact O-CG2 3.48Å; V425-V429 PolarHBondContact O-N 3.28Å; V425-L437 HydrophobicContact CB-CD2 4.21Å; V425-L437 HydrophobicContact CG1-CD2 3.86Å; V425-L437 HydrophobicContact CG2-CD2 4.26Å; V425-L440 HydrophobicContact CG2-CD1 4.23Å; V425-A445 HydrophobicContact CG2-CB 4.31Å; V425-L447 HydrophobicContact CG1-CD2 4.35Å; V425-L447 HydrophobicContact CG2-CD2 3.98Å
426Y91.6Very high90.2Very high99 Ų9962.5 Ų62.539%0.38830%0.302SS..Hα-helixtrans-55.8-51.5174.7166.1-103.8000111.6P422 M423 A428 V429 C430 Y460P422-Y426 VanDerWaalsContact O-CB 3.26Å; P422-Y426 WeakPolarHBondContact O-CB 3.36Å; P422-Y426 PolarHBondContact O-N 2.98Å; M423-Y426 PolarHBondContact O-N 3.5Å; Y426-A428 VanDerWaalsContact C-N 3.28Å; Y426-A428 PolarHBondContact O-N 3.22Å; Y426-V429 WeakPolarHBondContact O-CB 3.47Å; Y426-V429 PolarHBondContact O-N 2.91Å; Y426-C430 WeakPolarHBondContact CE2-SG 3.37Å; Y426-C430 PolarHBondContact O-N 3.26Å; Y426-Y460 AromaticContact CD2-CD1 3.81Å; Y426-Y460 HydrophobicContact CD2-CD1 3.81Å; Y426-Y460 AromaticContact CD2-CD2 3.67Å; Y426-Y460 HydrophobicContact CD2-CD2 3.67Å; Y426-Y460 AromaticContact CD2-CE1 3.79Å; Y426-Y460 HydrophobicContact CD2-CE1 3.79Å; Y426-Y460 AromaticContact CD2-CE2 3.65Å; Y426-Y460 HydrophobicContact CD2-CE2 3.65Å; Y426-Y460 AromaticContact CD2-CG 3.72Å; Y426-Y460 HydrophobicContact CD2-CG 3.72Å; Y426-Y460 AromaticContact CD2-CZ 3.68Å; Y426-Y460 AromaticContact CE2-CD1 3.46Å; Y426-Y460 HydrophobicContact CE2-CD1 3.46Å; Y426-Y460 VanDerWaalsContact CE2-CD1 3.46Å; Y426-Y460 HydrophobicContact CE2-CD2 4.21Å; Y426-Y460 AromaticContact CE2-CE1 3.44Å; Y426-Y460 HydrophobicContact CE2-CE1 3.44Å; Y426-Y460 VanDerWaalsContact CE2-CE1 3.44Å; Y426-Y460 HydrophobicContact CE2-CE2 4.21Å; Y426-Y460 AromaticContact CE2-CG 3.84Å; Y426-Y460 HydrophobicContact CE2-CG 3.84Å; Y426-Y460 AromaticContact CE2-CZ 3.82Å
427Q92.4Very high90.5Very high92 Ų9261.5 Ų61.543%0.4330%0.297SS..Hα-helixtrans-59.8-39.8-179.7-17564.18.800112.1M423 L424 V425 V429 C430 Q431M423-Q427 WeakPolarHBondContact O-CB 3.2Å; M423-Q427 PolarHBondContact O-N 3.01Å; L424-Q427 PolarHBondContact O-N 3.06Å; V425-Q427 PolarHBondContact O-N 3.49Å; Q427-V429 VanDerWaalsContact C-N 3.34Å; Q427-C430 PolarHBondContact O-N 2.92Å; Q427-Q431 WeakPolarHBondContact O-CG 3.44Å; Q427-Q431 PolarHBondContact O-N 3.41Å
428A94.3Very high91Very high0 Ų063.7 Ų63.70%031%0.308CS..Hα-helixtrans-64.8-37.317600000112.4L424 V425 Y426 Q431 G432 N433 L436 L437 L440L424-A428 WeakPolarHBondContact O-CB 3.14Å; L424-A428 PolarHBondContact O-N 3.11Å; V425-A428 PolarHBondContact O-N 3.41Å; Y426-A428 VanDerWaalsContact C-N 3.28Å; Y426-A428 PolarHBondContact O-N 3.22Å; A428-Q431 PolarHBondContact O-N 3.14Å; A428-G432 PolarHBondContact O-N 2.71Å; A428-N433 PolarHBondContact O-N 3.04Å; A428-L436 HydrophobicContact CB-CB 4.13Å; A428-L436 HydrophobicContact CB-CD2 3.73Å; A428-L436 HydrophobicContact CB-CG 3.88Å; A428-L437 HydrophobicContact CB-CD2 3.59Å; A428-L437 HydrophobicContact CB-CG 3.78Å; A428-L440 HydrophobicContact CB-CD1 4.41Å
429V95Very high91.5Very high0 Ų062.4 Ų62.40%031%0.31CS..Hα-helixtrans-65.5-47.4174.6171.10000111.1V425 Y426 Q427 Q431 G432 L437 A461 L464 M469 L473V425-V429 WeakPolarHBondContact O-CG2 3.48Å; V425-V429 PolarHBondContact O-N 3.28Å; Y426-V429 WeakPolarHBondContact O-CB 3.47Å; Y426-V429 PolarHBondContact O-N 2.91Å; Q427-V429 VanDerWaalsContact C-N 3.34Å; V429-Q431 PolarHBondContact O-N 3.05Å; V429-G432 PolarHBondContact O-N 2.95Å; V429-L437 HydrophobicContact CG2-CD1 4.09Å; V429-A461 HydrophobicContact CG1-CB 3.92Å; V429-L464 HydrophobicContact CG1-CD1 4.5Å; V429-M469 HydrophobicContact CG1-CG 4.21Å; V429-M469 HydrophobicContact CG2-CG 4.35Å; V429-M469 HydrophobicContact CG2-SD 4.24Å; V429-L473 HydrophobicContact CG2-CD1 4.38Å
430C93Very high91.8Very high49 Ų4957.2 Ų57.233%0.33128%0.283SS..Hα-helixtrans-60.7-25.6178.2-70.90000113.9Y426 Q427Y426-C430 WeakPolarHBondContact CE2-SG 3.37Å; Y426-C430 PolarHBondContact O-N 3.26Å; Q427-C430 PolarHBondContact O-N 2.92Å
431Q93.5Very high91.7Very high112 Ų11260 Ų6052%0.52330%0.295SS..THydrogen-bonded Turntrans-92.8-0.4176.8-68179.7-3.700113.7Q427 A428 V429 N433Q427-Q431 WeakPolarHBondContact O-CG 3.44Å; Q427-Q431 PolarHBondContact O-N 3.41Å; A428-Q431 PolarHBondContact O-N 3.14Å; V429-Q431 PolarHBondContact O-N 3.05Å; Q431-N433 HydrophobicContact CB-CB 4.16Å; Q431-N433 PolarHBondContact O-N 3.43Å
432G93.7Very high91.6Very high31 Ų3163.8 Ų63.832%0.3232%0.323SS..THydrogen-bonded Turntrans63.818.4-172.100000113.7A428 V429 I434A428-G432 PolarHBondContact O-N 2.71Å; V429-G432 PolarHBondContact O-N 2.95Å; G432-I434 PolarHBondContact O-N 2.94Å; G432-I434 VanDerWaalsContact O-N 3.09Å
433N95.4Very high91Very high57 Ų5764.2 Ų64.231%0.30533%0.331SS..  trans-89.977.3-167.9-166.7-16.9000112.7A428 Q431 R435 L436 L437A428-N433 PolarHBondContact O-N 3.04Å; Q431-N433 HydrophobicContact CB-CB 4.16Å; Q431-N433 PolarHBondContact O-N 3.43Å; N433-R435 PolarHBondContact O-N 2.62Å; N433-R435 PolarHBondContact OD1-N 3.18Å; N433-L436 HydrophobicContact CB-CB 4.06Å; N433-L436 VanDerWaalsContact CG-CB 3.46Å; N433-L436 PolarHBondContact O-N 3.37Å; N433-L436 VanDerWaalsContact O-N 3.15Å; N433-L436 PolarHBondContact OD1-N 3.48Å; N433-L437 PolarHBondContact O-N 3.18Å
434I95.2Very high90.5Very high35 Ų3559.8 Ų59.818%0.17932%0.319CS..Hα-helixtrans-58.5-32.8177.4-62.9173.4000111.9G432 L437 K438 E468 M469 F472G432-I434 PolarHBondContact O-N 2.94Å; G432-I434 VanDerWaalsContact O-N 3.09Å; I434-L437 PolarHBondContact O-N 3.46Å; I434-K438 HydrophobicContact CG2-CD 4.4Å; I434-K438 WeakPolarHBondContact O-CG 3.22Å; I434-K438 PolarHBondContact O-N 3.3Å; I434-E468 HydrophobicContact CD1-CB 4.17Å; I434-M469 HydrophobicContact CG1-CE 3.6Å; I434-M469 HydrophobicContact CG1-SD 3.94Å; I434-F472 HydrophobicContact CD1-CB 4.22Å; I434-F472 HydrophobicContact CG1-CB 4.47Å; I434-F472 HydrophobicContact CG2-CB 4.38Å; I434-F472 HydrophobicContact CG2-CD1 4Å; I434-F472 HydrophobicContact CG2-CD2 3.8Å; I434-F472 HydrophobicContact CG2-CE1 4.25Å; I434-F472 HydrophobicContact CG2-CE2 4.07Å; I434-F472 HydrophobicContact CG2-CG 3.76Å; I434-F472 HydrophobicContact CG2-CZ 4.29Å
435R94.7Very high90.1Very high218 Ų21857.3 Ų57.382%0.82331%0.308SS*.Hα-helixtrans-64-42.3178.2-66-178-177171.31.7111.4N433 K438 S439N433-R435 PolarHBondContact O-N 2.62Å; N433-R435 PolarHBondContact OD1-N 3.18Å; R435-K438 PolarHBondContact O-N 3.49Å; R435-S439 PolarHBondContact O-N 3.17Å; R435-S439 VanDerWaalsContact O-N 3.08Å
436L92.5Very high89.7Confident60 Ų6059.6 Ų59.631%0.31432%0.321SS..Hα-helixtrans-64.5-42.6175.5179.757.7000111.2A428 N433 K438 S439 L440A428-L436 HydrophobicContact CB-CB 4.13Å; A428-L436 HydrophobicContact CB-CD2 3.73Å; A428-L436 HydrophobicContact CB-CG 3.88Å; N433-L436 HydrophobicContact CB-CB 4.06Å; N433-L436 VanDerWaalsContact CG-CB 3.46Å; N433-L436 PolarHBondContact O-N 3.37Å; N433-L436 VanDerWaalsContact O-N 3.15Å; N433-L436 PolarHBondContact OD1-N 3.48Å; L436-K438 VanDerWaalsContact C-N 3.33Å; L436-K438 PolarHBondContact O-N 3.4Å; L436-S439 WeakPolarHBondContact O-CB 3.19Å; L436-S439 PolarHBondContact O-N 3.21Å; L436-S439 VanDerWaalsContact O-N 3.13Å; L436-L440 HydrophobicContact CD1-CD1 4.39Å; L436-L440 HydrophobicContact CD1-CG 4.13Å; L436-L440 HydrophobicContact CG-CD1 4.09Å; L436-L440 HydrophobicContact CG-CG 4.31Å; L436-L440 WeakPolarHBondContact O-CG 3.25Å; L436-L440 PolarHBondContact O-N 3.18Å
437L92.7Very high89.6Confident0 Ų055.4 Ų55.40%031%0.306CS..Hα-helixtrans-59.5-41.6175.3-72.3-178.7000112.9V425 A428 V429 N433 I434 S439 L440 K441 L447 M469 F472 L473V425-L437 HydrophobicContact CB-CD2 4.21Å; V425-L437 HydrophobicContact CG1-CD2 3.86Å; V425-L437 HydrophobicContact CG2-CD2 4.26Å; A428-L437 HydrophobicContact CB-CD2 3.59Å; A428-L437 HydrophobicContact CB-CG 3.78Å; V429-L437 HydrophobicContact CG2-CD1 4.09Å; N433-L437 PolarHBondContact O-N 3.18Å; I434-L437 PolarHBondContact O-N 3.46Å; L437-S439 VanDerWaalsContact C-N 3.33Å; L437-S439 PolarHBondContact O-N 2.94Å; L437-L440 HydrophobicContact CD2-CD1 4.5Å; L437-L440 PolarHBondContact O-N 3.15Å; L437-K441 WeakPolarHBondContact O-CB 3.44Å; L437-K441 PolarHBondContact O-N 3.19Å; L437-L447 HydrophobicContact CD2-CD2 4.1Å; L437-M469 HydrophobicContact CD1-CE 4.02Å; L437-M469 HydrophobicContact CD1-SD 3.28Å; L437-M469 WeakPolarHBondContact CD1-SD 3.25Å; L437-F472 HydrophobicContact CB-CE1 3.77Å; L437-F472 HydrophobicContact CB-CZ 4.47Å; L437-F472 HydrophobicContact CD1-CD1 4.05Å; L437-F472 HydrophobicContact CD1-CE1 3.92Å; L437-L473 HydrophobicContact CD1-CD2 4.09Å
438K91.9Very high89.3Confident120 Ų12052.3 Ų52.352%0.52229%0.293SS..Hα-helixtrans-60.6-42.8174.5-72.3177178.5-179.90111.7I434 R435 L436 K441 S442 F472I434-K438 HydrophobicContact CG2-CD 4.4Å; I434-K438 WeakPolarHBondContact O-CG 3.22Å; I434-K438 PolarHBondContact O-N 3.3Å; R435-K438 PolarHBondContact O-N 3.49Å; L436-K438 VanDerWaalsContact C-N 3.33Å; L436-K438 PolarHBondContact O-N 3.4Å; K438-K441 PolarHBondContact O-N 3.14Å; K438-S442 PolarHBondContact O-N 2.66Å; K438-S442 PolarHBondContact O-OG 3.16Å; K438-F472 HydrophobicContact CD-CE2 4.36Å; K438-F472 HydrophobicContact CG-CE2 3.87Å; K438-F472 HydrophobicContact CG-CZ 3.69Å
439S89.5Confident88.9Confident70 Ų7053.7 Ų53.749%0.4930%0.302SS..Hα-helixtrans-64.9-46.8177-176.70000112.3R435 L436 L437 K441 S442 G443R435-S439 PolarHBondContact O-N 3.17Å; R435-S439 VanDerWaalsContact O-N 3.08Å; L436-S439 WeakPolarHBondContact O-CB 3.19Å; L436-S439 PolarHBondContact O-N 3.21Å; L436-S439 VanDerWaalsContact O-N 3.13Å; L437-S439 VanDerWaalsContact C-N 3.33Å; L437-S439 PolarHBondContact O-N 2.94Å; S439-K441 VanDerWaalsContact C-N 3.33Å; S439-K441 PolarHBondContact O-N 3.11Å; S439-S442 WeakPolarHBondContact CA-OG 3.47Å; S439-S442 PolarHBondContact O-N 3Å; S439-S442 PolarHBondContact O-OG 3Å; S439-G443 PolarHBondContact O-N 2.82Å
440L88.6Confident88.6Confident15 Ų1556.7 Ų56.78%0.07932%0.32CS..Hα-helixtrans-58.6-46.2176.1-71.1173.1000111L424 V425 A428 L436 L437 S442 G443 G444 A445L424-L440 HydrophobicContact CB-CD1 3.81Å; L424-L440 HydrophobicContact CB-CD2 3.95Å; L424-L440 HydrophobicContact CD1-CD2 3.82Å; V425-L440 HydrophobicContact CG2-CD1 4.23Å; A428-L440 HydrophobicContact CB-CD1 4.41Å; L436-L440 HydrophobicContact CD1-CD1 4.39Å; L436-L440 HydrophobicContact CD1-CG 4.13Å; L436-L440 HydrophobicContact CG-CD1 4.09Å; L436-L440 HydrophobicContact CG-CG 4.31Å; L436-L440 WeakPolarHBondContact O-CG 3.25Å; L436-L440 PolarHBondContact O-N 3.18Å; L437-L440 HydrophobicContact CD2-CD1 4.5Å; L437-L440 PolarHBondContact O-N 3.15Å; L440-S442 PolarHBondContact O-N 3.5Å; L440-G443 CarbonylContact O-C 3.41Å; L440-G443 WeakPolarHBondContact O-CA 3.43Å; L440-G443 PolarHBondContact O-N 2.8Å; L440-G444 PolarHBondContact O-N 3.25Å; L440-A445 HydrophobicContact CB-CB 3.78Å; L440-A445 WeakPolarHBondContact O-CB 3.46Å; L440-A445 PolarHBondContact O-N 3.22Å
441K86Confident88.4Confident74 Ų7455.9 Ų55.932%0.32231%0.313SS..Hα-helixtrans-60.4-45.3176.5-178.8-174.8160.7-167.80111.8L437 K438 S439 G443 G444 L447 E476L437-K441 WeakPolarHBondContact O-CB 3.44Å; L437-K441 PolarHBondContact O-N 3.19Å; K438-K441 PolarHBondContact O-N 3.14Å; S439-K441 VanDerWaalsContact C-N 3.33Å; S439-K441 PolarHBondContact O-N 3.11Å; K441-G443 PolarHBondContact O-N 3.09Å; K441-G444 PolarHBondContact O-N 3.35Å; K441-L447 HydrophobicContact CB-CD1 4.41Å; K441-L447 HydrophobicContact CB-CG 4.4Å; K441-L447 HydrophobicContact CD-CD1 4.05Å; K441-E476 WeakPolarHBondContact CE-OE2 3.31Å; K441-E476 IonicContact NZ-OE1 2.86Å; K441-E476 PolarHBondContact NZ-OE1 2.99Å; K441-E476 IonicContact NZ-OE2 3.51Å; K441-E476 PolarHBondContact NZ-OE2 3.4Å
442S83.2Confident88Confident95 Ų9560.1 Ų60.166%0.66433%0.325SS*.Hα-helixtrans-62.8-26.117562.30000113K438 S439 L440 G444K438-S442 PolarHBondContact O-N 2.66Å; K438-S442 PolarHBondContact O-OG 3.16Å; S439-S442 WeakPolarHBondContact CA-OG 3.47Å; S439-S442 PolarHBondContact O-N 3Å; S439-S442 PolarHBondContact O-OG 3Å; L440-S442 PolarHBondContact O-N 3.5Å; S442-G444 VanDerWaalsContact C-N 3.31Å
443G76.4Confident87.7Confident28 Ų2861.7 Ų61.729%0.28933%0.325SS..THydrogen-bonded Turntrans-86.511.6173.500000114.6Y421 S439 L440 K441Y421-G443 PolarHBondContact OH-O 3.21Å; S439-G443 PolarHBondContact O-N 2.82Å; L440-G443 CarbonylContact O-C 3.41Å; L440-G443 WeakPolarHBondContact O-CA 3.43Å; L440-G443 PolarHBondContact O-N 2.8Å; K441-G443 PolarHBondContact O-N 3.09Å
444G77.5Confident87.4Confident40 Ų4061.7 Ų61.741%0.41232%0.321SS..THydrogen-bonded Turntrans96.53.6175.900000115.9L440 K441 S442 V446L440-G444 PolarHBondContact O-N 3.25Å; K441-G444 PolarHBondContact O-N 3.35Å; S442-G444 VanDerWaalsContact C-N 3.31Å; G444-V446 PolarHBondContact O-N 2.79Å
445A83.4Confident87.3Confident6 Ų662 Ų625%0.0532%0.32CS..  trans-67129.4176.100000111.5Y421 V425 L440Y421-A445 HydrophobicContact CD1-CB 3.36Å; Y421-A445 HydrophobicContact CE1-CB 3.78Å; Y421-A445 HydrophobicContact CG-CB 3.86Å; V425-A445 HydrophobicContact CG2-CB 4.31Å; L440-A445 HydrophobicContact CB-CB 3.78Å; L440-A445 WeakPolarHBondContact O-CB 3.46Å; L440-A445 PolarHBondContact O-N 3.22Å
446V83.7Confident87.3Confident51 Ų5151.7 Ų51.731%0.30928%0.281SS..  trans-88.5108.9172.9179.50000108.7G444 T448 C449G444-V446 PolarHBondContact O-N 2.79Å; V446-T448 WeakPolarHBondContact CG1-OG1 3.47Å; V446-T448 PolarHBondContact O-N 3.1Å; V446-T448 VanDerWaalsContact O-N 3.14Å; V446-C449 WeakPolarHBondContact O-CB 3.49Å; V446-C449 PolarHBondContact O-N 2.92Å; V446-C449 VanDerWaalsContact O-N 3.1Å; V446-C449 PolarHBondContact O-SG 3.1Å
447L88.8Confident87.4Confident11 Ų1149 Ų496%0.05827%0.268CS..THydrogen-bonded Turntrans-67.5-13.3-176.5-60.9-176.3000114.1V425 L437 K441 C449 S457 F472 E476 V478V425-L447 HydrophobicContact CG1-CD2 4.35Å; V425-L447 HydrophobicContact CG2-CD2 3.98Å; L437-L447 HydrophobicContact CD2-CD2 4.1Å; K441-L447 HydrophobicContact CB-CD1 4.41Å; K441-L447 HydrophobicContact CB-CG 4.4Å; K441-L447 HydrophobicContact CD-CD1 4.05Å; L447-C449 VanDerWaalsContact C-N 3.32Å; L447-S457 PolarHBondContact O-OG 2.96Å; L447-F472 HydrophobicContact CD1-CE1 4.15Å; L447-F472 HydrophobicContact CD1-CZ 4.44Å; L447-E476 HydrophobicContact CD1-CB 3.95Å; L447-E476 HydrophobicContact CD1-CG 3.82Å; L447-V478 HydrophobicContact CB-CG2 4.2Å
448T86.8Confident87.6Confident26 Ų2649 Ų4916%0.1627%0.268CS..THydrogen-bonded Turntrans-89.55.8175.869.70000113.2V446 V478V446-T448 WeakPolarHBondContact CG1-OG1 3.47Å; V446-T448 PolarHBondContact O-N 3.1Å; V446-T448 VanDerWaalsContact O-N 3.14Å; T448-V478 HydrophobicContact CG2-CG2 4.28Å
449C86.2Confident87.9Confident30 Ų3043.3 Ų43.320%0.20324%0.243CC..  trans-61157.7174.762.70000111.4P422 V446 L447P422-C449 HydrophobicContact CG-CB 3.97Å; V446-C449 WeakPolarHBondContact O-CB 3.49Å; V446-C449 PolarHBondContact O-N 2.92Å; V446-C449 VanDerWaalsContact O-N 3.1Å; V446-C449 PolarHBondContact O-SG 3.1Å; L447-C449 VanDerWaalsContact C-N 3.32Å
450V88.5Confident88.2Confident62 Ų6241.7 Ų41.738%0.37623%0.226SC..BIsolated β-bridgetrans-119.8150.9176.6-63.40000110.4R455 T456 T482V450-R455 VanDerWaalsContact CA-O 3.25Å; V450-R455 WeakPolarHBondContact CA-O 3.47Å; V450-T456 HydrophobicContact CG1-CG2 3.73Å; V450-T482 HydrophobicContact CG1-CG2 4.32Å
451D88.3Confident88.6Confident33 Ų3341 Ų4118%0.17622%0.223CC..  trans-81.3-172.7172.283.3-27000112.1M453 R454 R455 Y460D451-M453 VanDerWaalsContact CG-N 3.33Å; D451-M453 PolarHBondContact O-N 3.26Å; D451-M453 VanDerWaalsContact OD1-C 3.29Å; D451-M453 VanDerWaalsContact OD1-CA 3.32Å; D451-M453 WeakPolarHBondContact OD1-CA 3.36Å; D451-M453 WeakPolarHBondContact OD1-CB 3.45Å; D451-M453 PolarHBondContact OD1-N 2.84Å; D451-M453 PolarHBondContact OD2-N 3.08Å; D451-R454 WeakPolarHBondContact O-CA 3.17Å; D451-R454 PolarHBondContact O-N 3.12Å; D451-R454 PolarHBondContact OD1-N 2.99Å; D451-R455 PolarHBondContact N-O 2.74Å; D451-R455 WeakPolarHBondContact OD1-CA 3.25Å; D451-R455 WeakPolarHBondContact OD1-CB 3.47Å; D451-R455 PolarHBondContact OD1-N 3.4Å; D451-Y460 VanDerWaalsContact CG-OH 3.25Å; D451-Y460 PolarHBondContact OD2-OH 3.17Å
452Y85.1Confident89.1Confident200 Ų20037.4 Ų37.478%0.78421%0.207SC*.THydrogen-bonded Turntrans-64.7-22.3176.968.6-85.8000113.5R454 N485Y452-R454 VanDerWaalsContact C-N 3.29Å; Y452-N485 PolarHBondContact O-ND2 2.56Å; Y452-N485 VanDerWaalsContact O-ND2 3.14Å
453M88Confident89.8Confident65 Ų6534.6 Ų34.632%0.3219%0.19SC..THydrogen-bonded Turntrans-86.42.8172.3-57.1-165.375.800113D451 R455 D484 N485D451-M453 VanDerWaalsContact CG-N 3.33Å; D451-M453 PolarHBondContact O-N 3.26Å; D451-M453 VanDerWaalsContact OD1-C 3.29Å; D451-M453 VanDerWaalsContact OD1-CA 3.32Å; D451-M453 WeakPolarHBondContact OD1-CA 3.36Å; D451-M453 WeakPolarHBondContact OD1-CB 3.45Å; D451-M453 PolarHBondContact OD1-N 2.84Å; D451-M453 PolarHBondContact OD2-N 3.08Å; M453-R455 HydrophobicContact CB-CG 4.14Å; M453-R455 PolarHBondContact O-N 3.4Å; M453-D484 WeakPolarHBondContact O-CB 3.42Å; M453-N485 WeakPolarHBondContact O-CB 3.42Å; M453-N485 PolarHBondContact O-N 2.86Å
454R88.9Confident90.7Very high56 Ų5637.4 Ų37.421%0.21120%0.198CC..  trans63.519.7-171.4-62.2-173.464.5149.2-1.2114.5N73 N170 D451 Y452 N485N73-R454 WeakPolarHBondContact ND2-CD 3.25Å; N170-R454 PolarHBondContact O-NH2 2.84Å; D451-R454 WeakPolarHBondContact O-CA 3.17Å; D451-R454 PolarHBondContact O-N 3.12Å; D451-R454 PolarHBondContact OD1-N 2.99Å; Y452-R454 VanDerWaalsContact C-N 3.29Å; R454-N485 WeakPolarHBondContact CD-OD1 3.23Å; R454-N485 WeakPolarHBondContact CG-OD1 3.26Å
455R93Very high91.6Very high41 Ų4136.7 Ų36.716%0.15519%0.19CC..  trans-80.3137.4174.6-69.6-176.1165.7-136-14.5110.5V450 D451 M453 H459 Y460 D484 E493V450-R455 VanDerWaalsContact CA-O 3.25Å; V450-R455 WeakPolarHBondContact CA-O 3.47Å; D451-R455 PolarHBondContact N-O 2.74Å; D451-R455 WeakPolarHBondContact OD1-CA 3.25Å; D451-R455 WeakPolarHBondContact OD1-CB 3.47Å; D451-R455 PolarHBondContact OD1-N 3.4Å; M453-R455 HydrophobicContact CB-CG 4.14Å; M453-R455 PolarHBondContact O-N 3.4Å; R455-H459 HydrophobicContact CB-CB 4.14Å; R455-H459 HydrophobicContact CG-CB 4.36Å; R455-Y460 HydrophobicContact CB-CE2 3.78Å; R455-D484 HydrophobicContact CG-CB 3.57Å; R455-D484 IonicContact CZ-OD2 3.23Å; R455-D484 IonicContact NE-OD2 2.78Å; R455-D484 PolarHBondContact NE-OD2 3.07Å; R455-D484 IonicContact NH2-OD2 2.67Å; R455-D484 PolarHBondContact NH2-OD2 2.91Å; R455-E493 IonicContact CZ-OE1 3.88Å; R455-E493 IonicContact CZ-OE2 3.32Å; R455-E493 IonicContact NH1-OE2 3.12Å; R455-E493 PolarHBondContact NH1-OE2 3.23Å; R455-E493 IonicContact NH2-OE1 2.8Å; R455-E493 PolarHBondContact NH2-OE1 3.2Å; R455-E493 IonicContact NH2-OE2 2.85Å; R455-E493 PolarHBondContact NH2-OE2 3.38Å; R455-E493 VanDerWaalsContact NH2-OE2 3.09Å
456T93.8Very high92.3Very high2 Ų240.3 Ų40.31%0.01221%0.206CC..BIsolated β-bridgetrans-90.9164.917264.30000110.8V450 L458 H459 Y460 T482V450-T456 HydrophobicContact CG1-CG2 3.73Å; T456-L458 PolarHBondContact O-N 3.01Å; T456-L458 VanDerWaalsContact O-N 3.12Å; T456-L458 PolarHBondContact OG1-N 3Å; T456-H459 PolarHBondContact N-ND1 3.38Å; T456-H459 WeakPolarHBondContact O-CB 3.28Å; T456-H459 PolarHBondContact O-N 3.08Å; T456-H459 PolarHBondContact OG1-ND1 3.02Å; T456-Y460 VanDerWaalsContact O-CD2 3.25Å; T456-Y460 WeakPolarHBondContact O-CD2 3.36Å; T456-T482 HydrophobicContact CG2-CG2 3.73Å
457S95.5Very high92.9Very high5 Ų540.9 Ų40.94%0.03521%0.207CC..Hα-helixtrans-47-37167.451.60000113.3L447 Y460 A461L447-S457 PolarHBondContact O-OG 2.96Å; S457-Y460 PolarHBondContact O-N 3.39Å; S457-A461 PolarHBondContact O-N 3.43Å
458L96.7Very high93.3Very high0 Ų047.3 Ų47.30%024%0.237CC..Hα-helixtrans-70.1-30.7179.8-16963.5000113.1T456 A462 V470 L473 L474 V478 V480 P490 L506T456-L458 PolarHBondContact O-N 3.01Å; T456-L458 VanDerWaalsContact O-N 3.12Å; T456-L458 PolarHBondContact OG1-N 3Å; L458-A462 WeakPolarHBondContact O-CB 3.27Å; L458-A462 PolarHBondContact O-N 3.48Å; L458-V470 HydrophobicContact CD1-CB 4.34Å; L458-V470 HydrophobicContact CD1-CG1 3.98Å; L458-V470 HydrophobicContact CD1-CG2 4.27Å; L458-L473 HydrophobicContact CB-CD1 4.42Å; L458-L473 HydrophobicContact CD1-CB 4.09Å; L458-L473 HydrophobicContact CD1-CD1 4.3Å; L458-L474 HydrophobicContact CD1-CD2 4.39Å; L458-L474 HydrophobicContact CD1-CG 4.34Å; L458-L474 HydrophobicContact CD2-CD2 3.81Å; L458-V478 HydrophobicContact CB-CG1 3.7Å; L458-V478 HydrophobicContact CD2-CG1 4.37Å; L458-V480 HydrophobicContact CD2-CG1 4.03Å; L458-P490 HydrophobicContact CB-CB 4.4Å; L458-P490 HydrophobicContact CB-CG 4.15Å; L458-P490 HydrophobicContact CD2-CB 4.06Å; L458-P490 HydrophobicContact CD2-CG 3.96Å; L458-P490 HydrophobicContact CG-CB 3.81Å; L458-P490 HydrophobicContact CG-CG 3.97Å; L458-L506 HydrophobicContact CD1-CD2 4.47Å; L458-L506 HydrophobicContact CD2-CD2 4.12Å; L458-L506 HydrophobicContact CG-CD2 4.48Å
459H97.1Very high93.7Very high0 Ų046.1 Ų46.10%023%0.229CC..Hα-helixtrans-61.2-47.4173.1-71.977.1000110.7R455 T456 A462 A463 T482 S488 E493R455-H459 HydrophobicContact CB-CB 4.14Å; R455-H459 HydrophobicContact CG-CB 4.36Å; T456-H459 PolarHBondContact N-ND1 3.38Å; T456-H459 WeakPolarHBondContact O-CB 3.28Å; T456-H459 PolarHBondContact O-N 3.08Å; T456-H459 PolarHBondContact OG1-ND1 3.02Å; H459-A462 PolarHBondContact O-N 3.13Å; H459-A463 WeakPolarHBondContact O-CB 3.48Å; H459-A463 PolarHBondContact O-N 3.39Å; H459-T482 PolarHBondContact CE1-O 3.39Å; H459-T482 PolarHBondContact NE2-O 2.98Å; H459-S488 PolarHBondContact NE2-O 2.98Å; H459-S488 VanDerWaalsContact NE2-O 3.1Å; H459-E493 HydrophobicContact CB-CG 4.39Å
460Y96Very high94.3Very high35 Ų3544.7 Ų44.714%0.13722%0.22CC..Hα-helixtrans-68.2-44.7-179.3-61.3-72000112.1Y426 D451 R455 T456 S457 A462 A463 L464Y426-Y460 AromaticContact CD2-CD1 3.81Å; Y426-Y460 HydrophobicContact CD2-CD1 3.81Å; Y426-Y460 AromaticContact CD2-CD2 3.67Å; Y426-Y460 HydrophobicContact CD2-CD2 3.67Å; Y426-Y460 AromaticContact CD2-CE1 3.79Å; Y426-Y460 HydrophobicContact CD2-CE1 3.79Å; Y426-Y460 AromaticContact CD2-CE2 3.65Å; Y426-Y460 HydrophobicContact CD2-CE2 3.65Å; Y426-Y460 AromaticContact CD2-CG 3.72Å; Y426-Y460 HydrophobicContact CD2-CG 3.72Å; Y426-Y460 AromaticContact CD2-CZ 3.68Å; Y426-Y460 AromaticContact CE2-CD1 3.46Å; Y426-Y460 HydrophobicContact CE2-CD1 3.46Å; Y426-Y460 VanDerWaalsContact CE2-CD1 3.46Å; Y426-Y460 HydrophobicContact CE2-CD2 4.21Å; Y426-Y460 AromaticContact CE2-CE1 3.44Å; Y426-Y460 HydrophobicContact CE2-CE1 3.44Å; Y426-Y460 VanDerWaalsContact CE2-CE1 3.44Å; Y426-Y460 HydrophobicContact CE2-CE2 4.21Å; Y426-Y460 AromaticContact CE2-CG 3.84Å; Y426-Y460 HydrophobicContact CE2-CG 3.84Å; Y426-Y460 AromaticContact CE2-CZ 3.82Å; D451-Y460 VanDerWaalsContact CG-OH 3.25Å; D451-Y460 PolarHBondContact OD2-OH 3.17Å; R455-Y460 HydrophobicContact CB-CE2 3.78Å; T456-Y460 VanDerWaalsContact O-CD2 3.25Å; T456-Y460 WeakPolarHBondContact O-CD2 3.36Å; S457-Y460 PolarHBondContact O-N 3.39Å; Y460-A462 VanDerWaalsContact C-N 3.27Å; Y460-A462 PolarHBondContact O-N 2.92Å; Y460-A463 PolarHBondContact O-N 3.45Å; Y460-L464 WeakPolarHBondContact O-CB 3.4Å; Y460-L464 VanDerWaalsContact O-CG 3.24Å; Y460-L464 WeakPolarHBondContact O-CG 3.41Å; Y460-L464 PolarHBondContact O-N 3.48Å
461A97.4Very high94.6Very high0 Ų045.4 Ų45.40%022%0.219CC..Hα-helixtrans-59.4-40.7176.700000111.7V429 S457 G465 E466 M469 V470 L473V429-A461 HydrophobicContact CG1-CB 3.92Å; S457-A461 PolarHBondContact O-N 3.43Å; A461-G465 PolarHBondContact O-N 3.46Å; A461-E466 PolarHBondContact O-N 2.84Å; A461-E466 VanDerWaalsContact O-N 3.15Å; A461-M469 HydrophobicContact CB-CB 4.17Å; A461-M469 HydrophobicContact CB-CG 3.73Å; A461-V470 HydrophobicContact CB-CG2 3.78Å; A461-L473 HydrophobicContact CB-CD1 3.8Å
462A97.8Very high95Very high0 Ų044.8 Ų44.80%022%0.215CC..Hα-helixtrans-67.6-41.9176.200000112.9L458 H459 Y460 G465 P490 E493 A494 H499 I502 L506L458-A462 WeakPolarHBondContact O-CB 3.27Å; L458-A462 PolarHBondContact O-N 3.48Å; H459-A462 PolarHBondContact O-N 3.13Å; Y460-A462 VanDerWaalsContact C-N 3.27Å; Y460-A462 PolarHBondContact O-N 2.92Å; A462-G465 PolarHBondContact O-N 2.77Å; A462-P490 HydrophobicContact CB-CB 4.28Å; A462-P490 VanDerWaalsContact CB-O 3.26Å; A462-P490 WeakPolarHBondContact CB-O 3.16Å; A462-E493 HydrophobicContact CB-CB 4.34Å; A462-A494 HydrophobicContact CB-CB 4.18Å; A462-H499 PolarHBondContact O-CD2 2.88Å; A462-I502 HydrophobicContact CB-CG2 4.25Å; A462-L506 HydrophobicContact CB-CD1 4.47Å
463A96.6Very high95.4Very high36 Ų3635.2 Ų35.230%0.29818%0.177SC..Hα-helixtrans-64.5-39.5176.700000112.3H459 Y460 E493 H499H459-A463 WeakPolarHBondContact O-CB 3.48Å; H459-A463 PolarHBondContact O-N 3.39Å; Y460-A463 PolarHBondContact O-N 3.45Å; A463-E493 HydrophobicContact CB-CB 4.09Å; A463-H499 PolarHBondContact O-NE2 3Å; A463-H499 VanDerWaalsContact O-NE2 3.17Å
464L96.2Very high95.7Very high87 Ų8732.7 Ų32.746%0.45517%0.165SC..Hα-helixtrans-77-17.7-177.9-68.4170.8000113.9V429 Y460 E466V429-L464 HydrophobicContact CG1-CD1 4.5Å; Y460-L464 WeakPolarHBondContact O-CB 3.4Å; Y460-L464 VanDerWaalsContact O-CG 3.24Å; Y460-L464 WeakPolarHBondContact O-CG 3.41Å; Y460-L464 PolarHBondContact O-N 3.48Å; L464-E466 HydrophobicContact CB-CG 4.03Å
465G96.7Very high95.9Very high25 Ų2532.3 Ų32.326%0.25817%0.171SC..THydrogen-bonded Turntrans85.415.1-177.800000114.8A461 A462 L467 H499 I502A461-G465 PolarHBondContact O-N 3.46Å; A462-G465 PolarHBondContact O-N 2.77Å; G465-L467 PolarHBondContact O-N 3.3Å; G465-H499 WeakPolarHBondContact CA-CE1 3.45Å; G465-H499 WeakPolarHBondContact CA-ND1 3.39Å; G465-H499 VanDerWaalsContact CA-NE2 3.34Å; G465-H499 WeakPolarHBondContact CA-NE2 3.28Å; G465-H499 PolarHBondContact N-NE2 2.9Å; G465-I502 VanDerWaalsContact C-CD1 3.41Å
466E96.3Very high95.8Very high82 Ų8232.3 Ų32.338%0.38317%0.173SC..  trans-82.782.6-173.3-70.3-66.2160.100111.8A461 L464 E468 M469 V470A461-E466 PolarHBondContact O-N 2.84Å; A461-E466 VanDerWaalsContact O-N 3.15Å; L464-E466 HydrophobicContact CB-CG 4.03Å; E466-E468 PolarHBondContact O-N 3.46Å; E466-M469 HydrophobicContact CB-CB 3.69Å; E466-M469 WeakPolarHBondContact O-CB 3.49Å; E466-M469 PolarHBondContact O-N 3.34Å; E466-M469 VanDerWaalsContact O-N 3.14Å; E466-V470 WeakPolarHBondContact O-CG2 3.43Å; E466-V470 PolarHBondContact O-N 2.84Å
467L96.9Very high95.6Very high63 Ų6332.6 Ų32.633%0.3318%0.176SC..Hα-helixtrans-57.4-44.2-174-178.663.6000113.4G465 M469 V470 Q471 A501 I502 L505G465-L467 PolarHBondContact O-N 3.3Å; L467-M469 VanDerWaalsContact C-N 3.31Å; L467-M469 PolarHBondContact O-N 3.2Å; L467-V470 PolarHBondContact O-N 2.99Å; L467-Q471 WeakPolarHBondContact O-CG 3.44Å; L467-Q471 PolarHBondContact O-N 3.09Å; L467-A501 HydrophobicContact CD2-CB 4.43Å; L467-I502 HydrophobicContact CB-CG1 4.35Å; L467-I502 HydrophobicContact CD1-CG1 3.83Å; L467-L505 HydrophobicContact CD1-CD2 3.76Å
468E96.8Very high95.5Very high145 Ų14532.6 Ų32.668%0.67818%0.175SC*.Hα-helixtrans-64-38.5178.7-66.1-172179.600111.8I434 E466 Q471 F472I434-E468 HydrophobicContact CD1-CB 4.17Å; E466-E468 PolarHBondContact O-N 3.46Å; E468-Q471 PolarHBondContact O-N 2.98Å; E468-F472 WeakPolarHBondContact O-CB 3.32Å; E468-F472 PolarHBondContact O-N 3.48Å
469M96.9Very high95.3Very high1 Ų133.1 Ų33.11%0.00518%0.179CC..Hα-helixtrans-65.8-44.8176.2-173.16170.500111.2V429 I434 L437 A461 E466 L467 Q471 F472 L473V429-M469 HydrophobicContact CG1-CG 4.21Å; V429-M469 HydrophobicContact CG2-CG 4.35Å; V429-M469 HydrophobicContact CG2-SD 4.24Å; I434-M469 HydrophobicContact CG1-CE 3.6Å; I434-M469 HydrophobicContact CG1-SD 3.94Å; L437-M469 HydrophobicContact CD1-CE 4.02Å; L437-M469 HydrophobicContact CD1-SD 3.28Å; L437-M469 WeakPolarHBondContact CD1-SD 3.25Å; A461-M469 HydrophobicContact CB-CB 4.17Å; A461-M469 HydrophobicContact CB-CG 3.73Å; E466-M469 HydrophobicContact CB-CB 3.69Å; E466-M469 WeakPolarHBondContact O-CB 3.49Å; E466-M469 PolarHBondContact O-N 3.34Å; E466-M469 VanDerWaalsContact O-N 3.14Å; L467-M469 VanDerWaalsContact C-N 3.31Å; L467-M469 PolarHBondContact O-N 3.2Å; M469-Q471 VanDerWaalsContact C-N 3.34Å; M469-Q471 PolarHBondContact O-N 3.26Å; M469-F472 PolarHBondContact O-N 2.96Å; M469-F472 HydrophobicContact SD-CD1 4.45Å; M469-L473 HydrophobicContact CG-CD1 4.06Å; M469-L473 HydrophobicContact CG-CG 4.42Å; M469-L473 VanDerWaalsContact O-CG 3.3Å; M469-L473 WeakPolarHBondContact O-CG 3.4Å; M469-L473 PolarHBondContact O-N 3.42Å; M469-L473 HydrophobicContact SD-CG 4.41Å
470V97.2Very high95.2Very high0 Ų033.6 Ų33.60%018%0.182CC..Hα-helixtrans-57.6-47.8174.5169.90000110.4L458 A461 E466 L467 F472 L473 L474 I502 L505 L506L458-V470 HydrophobicContact CD1-CB 4.34Å; L458-V470 HydrophobicContact CD1-CG1 3.98Å; L458-V470 HydrophobicContact CD1-CG2 4.27Å; A461-V470 HydrophobicContact CB-CG2 3.78Å; E466-V470 WeakPolarHBondContact O-CG2 3.43Å; E466-V470 PolarHBondContact O-N 2.84Å; L467-V470 PolarHBondContact O-N 2.99Å; V470-F472 VanDerWaalsContact C-N 3.32Å; V470-F472 PolarHBondContact O-N 3.08Å; V470-L473 PolarHBondContact O-N 2.7Å; V470-L474 HydrophobicContact CG1-CD1 3.83Å; V470-L474 HydrophobicContact CG1-CG 4.36Å; V470-L474 WeakPolarHBondContact O-CB 3.44Å; V470-L474 VanDerWaalsContact O-CG 3.23Å; V470-L474 WeakPolarHBondContact O-CG 3.42Å; V470-L474 PolarHBondContact O-N 3.29Å; V470-I502 HydrophobicContact CG1-CG2 4.27Å; V470-I502 HydrophobicContact CG2-CD1 4.02Å; V470-I502 HydrophobicContact CG2-CG1 4.31Å; V470-I502 HydrophobicContact CG2-CG2 4.09Å; V470-L505 HydrophobicContact CB-CD2 4.48Å; V470-L505 HydrophobicContact CG1-CD2 3.71Å; V470-L505 HydrophobicContact CG1-CG 4.49Å; V470-L506 HydrophobicContact CG1-CD2 4.34Å
471Q96.3Very high95.2Very high78 Ų7833.2 Ų33.236%0.36418%0.182SC..Hα-helixtrans-59.4-43178-72.1179.111.100112.4L467 E468 M469 S475 L505L467-Q471 WeakPolarHBondContact O-CG 3.44Å; L467-Q471 PolarHBondContact O-N 3.09Å; E468-Q471 PolarHBondContact O-N 2.98Å; M469-Q471 VanDerWaalsContact C-N 3.34Å; M469-Q471 PolarHBondContact O-N 3.26Å; Q471-S475 PolarHBondContact O-N 3.06Å; Q471-S475 VanDerWaalsContact O-N 3.09Å; Q471-L505 HydrophobicContact CG-CD2 3.51Å
472F95.2Very high95Very high19 Ų1934 Ų348%0.08319%0.186CC..Hα-helixtrans-62.6-50.9176.7174.8-105.8000111.7I434 L437 K438 L447 E468 M469 V470 L474 S475 E476I434-F472 HydrophobicContact CD1-CB 4.22Å; I434-F472 HydrophobicContact CG1-CB 4.47Å; I434-F472 HydrophobicContact CG2-CB 4.38Å; I434-F472 HydrophobicContact CG2-CD1 4Å; I434-F472 HydrophobicContact CG2-CD2 3.8Å; I434-F472 HydrophobicContact CG2-CE1 4.25Å; I434-F472 HydrophobicContact CG2-CE2 4.07Å; I434-F472 HydrophobicContact CG2-CG 3.76Å; I434-F472 HydrophobicContact CG2-CZ 4.29Å; L437-F472 HydrophobicContact CB-CE1 3.77Å; L437-F472 HydrophobicContact CB-CZ 4.47Å; L437-F472 HydrophobicContact CD1-CD1 4.05Å; L437-F472 HydrophobicContact CD1-CE1 3.92Å; K438-F472 HydrophobicContact CD-CE2 4.36Å; K438-F472 HydrophobicContact CG-CE2 3.87Å; K438-F472 HydrophobicContact CG-CZ 3.69Å; L447-F472 HydrophobicContact CD1-CE1 4.15Å; L447-F472 HydrophobicContact CD1-CZ 4.44Å; E468-F472 WeakPolarHBondContact O-CB 3.32Å; E468-F472 PolarHBondContact O-N 3.48Å; M469-F472 PolarHBondContact O-N 2.96Å; M469-F472 HydrophobicContact SD-CD1 4.45Å; V470-F472 VanDerWaalsContact C-N 3.32Å; V470-F472 PolarHBondContact O-N 3.08Å; F472-L474 VanDerWaalsContact C-N 3.31Å; F472-L474 PolarHBondContact O-N 3.04Å; F472-S475 WeakPolarHBondContact O-CB 3.44Å; F472-S475 PolarHBondContact O-N 2.94Å; F472-S475 VanDerWaalsContact O-N 3.11Å; F472-S475 PolarHBondContact O-OG 3.47Å; F472-E476 HydrophobicContact CD2-CG 4.47Å; F472-E476 HydrophobicContact CE1-CG 4.16Å; F472-E476 HydrophobicContact CE2-CG 3.98Å; F472-E476 HydrophobicContact CZ-CG 3.82Å; F472-E476 WeakPolarHBondContact O-CG 3.37Å; F472-E476 PolarHBondContact O-N 3.48Å; F472-E476 VanDerWaalsContact O-N 3.14Å
473L95Very high94.8Very high0 Ų035.3 Ų35.30%019%0.192CC..Hα-helixtrans-61.6-37.7-179.1-68.2173.4000112.5V429 L437 L458 A461 M469 V470 E476 G477 V478V429-L473 HydrophobicContact CG2-CD1 4.38Å; L437-L473 HydrophobicContact CD1-CD2 4.09Å; L458-L473 HydrophobicContact CB-CD1 4.42Å; L458-L473 HydrophobicContact CD1-CB 4.09Å; L458-L473 HydrophobicContact CD1-CD1 4.3Å; A461-L473 HydrophobicContact CB-CD1 3.8Å; M469-L473 HydrophobicContact CG-CD1 4.06Å; M469-L473 HydrophobicContact CG-CG 4.42Å; M469-L473 VanDerWaalsContact O-CG 3.3Å; M469-L473 WeakPolarHBondContact O-CG 3.4Å; M469-L473 PolarHBondContact O-N 3.42Å; M469-L473 HydrophobicContact SD-CG 4.41Å; V470-L473 PolarHBondContact O-N 2.7Å; L473-E476 WeakPolarHBondContact O-CB 3.26Å; L473-E476 PolarHBondContact O-N 3.16Å; L473-G477 PolarHBondContact O-N 2.98Å; L473-V478 HydrophobicContact CB-CB 4.35Å; L473-V478 HydrophobicContact CB-CG2 4.15Å; L473-V478 HydrophobicContact CD2-CG2 4.25Å; L473-V478 WeakPolarHBondContact O-CB 3.26Å; L473-V478 WeakPolarHBondContact O-CG2 3.35Å; L473-V478 PolarHBondContact O-N 2.86Å; L473-V478 VanDerWaalsContact O-N 3.15Å
474L94.5Very high94.6Very high12 Ų1233.6 Ų33.66%0.06318%0.178CC..Hα-helixtrans-65.4-41.3174.1-68.8172.1000112R229 L458 V470 F472 E476 G477 V480 L505 L506R229-L474 HydrophobicContact CG-CB 4.17Å; L458-L474 HydrophobicContact CD1-CD2 4.39Å; L458-L474 HydrophobicContact CD1-CG 4.34Å; L458-L474 HydrophobicContact CD2-CD2 3.81Å; V470-L474 HydrophobicContact CG1-CD1 3.83Å; V470-L474 HydrophobicContact CG1-CG 4.36Å; V470-L474 WeakPolarHBondContact O-CB 3.44Å; V470-L474 VanDerWaalsContact O-CG 3.23Å; V470-L474 WeakPolarHBondContact O-CG 3.42Å; V470-L474 PolarHBondContact O-N 3.29Å; F472-L474 VanDerWaalsContact C-N 3.31Å; F472-L474 PolarHBondContact O-N 3.04Å; L474-E476 PolarHBondContact O-N 2.91Å; L474-G477 PolarHBondContact O-N 3.36Å; L474-V480 HydrophobicContact CD2-CG1 3.44Å; L474-V480 VanDerWaalsContact CD2-CG1 3.44Å; L474-L505 HydrophobicContact CD1-CD1 4.42Å; L474-L505 HydrophobicContact CD1-CD2 4.1Å; L474-L505 HydrophobicContact CD1-CG 3.93Å; L474-L506 HydrophobicContact CD1-CD2 4.36Å; L474-L506 HydrophobicContact CD2-CD2 4.28Å
475S92.1Very high94.3Very high48 Ų4831.9 Ų31.934%0.33617%0.169SC..Hα-helixtrans-63.5-19.5174.678.20000113.5R227 Q471 F472R227-S475 WeakPolarHBondContact CB-O 3.29Å; Q471-S475 PolarHBondContact O-N 3.06Å; Q471-S475 VanDerWaalsContact O-N 3.09Å; F472-S475 WeakPolarHBondContact O-CB 3.44Å; F472-S475 PolarHBondContact O-N 2.94Å; F472-S475 VanDerWaalsContact O-N 3.11Å; F472-S475 PolarHBondContact O-OG 3.47Å
476E90.4Very high93.9Very high41 Ų4134.2 Ų34.219%0.19218%0.182CC..THydrogen-bonded Turntrans-91.20.6176.1-69.2-64.3174.600113.4K441 L447 F472 L473 L474K441-E476 WeakPolarHBondContact CE-OE2 3.31Å; K441-E476 IonicContact NZ-OE1 2.86Å; K441-E476 PolarHBondContact NZ-OE1 2.99Å; K441-E476 IonicContact NZ-OE2 3.51Å; K441-E476 PolarHBondContact NZ-OE2 3.4Å; L447-E476 HydrophobicContact CD1-CB 3.95Å; L447-E476 HydrophobicContact CD1-CG 3.82Å; F472-E476 HydrophobicContact CD2-CG 4.47Å; F472-E476 HydrophobicContact CE1-CG 4.16Å; F472-E476 HydrophobicContact CE2-CG 3.98Å; F472-E476 HydrophobicContact CZ-CG 3.82Å; F472-E476 WeakPolarHBondContact O-CG 3.37Å; F472-E476 PolarHBondContact O-N 3.48Å; F472-E476 VanDerWaalsContact O-N 3.14Å; L473-E476 WeakPolarHBondContact O-CB 3.26Å; L473-E476 PolarHBondContact O-N 3.16Å; L474-E476 PolarHBondContact O-N 2.91Å
477G89.4Confident93.6Very high7 Ų732.3 Ų32.37%0.07217%0.174CC..THydrogen-bonded Turntrans79.321.5176.800000114.2R225 L473 L474 S479R225-G477 WeakPolarHBondContact CD-O 3.34Å; L473-G477 PolarHBondContact O-N 2.98Å; L474-G477 PolarHBondContact O-N 3.36Å; G477-S479 PolarHBondContact O-N 2.78Å
478V93.3Very high93.4Very high5 Ų529.3 Ų29.33%0.0316%0.158CC..  trans-67.6127.5173.4-176.90000109.7L447 T448 L458 L473L447-V478 HydrophobicContact CB-CG2 4.2Å; T448-V478 HydrophobicContact CG2-CG2 4.28Å; L458-V478 HydrophobicContact CB-CG1 3.7Å; L458-V478 HydrophobicContact CD2-CG1 4.37Å; L473-V478 HydrophobicContact CB-CB 4.35Å; L473-V478 HydrophobicContact CB-CG2 4.15Å; L473-V478 HydrophobicContact CD2-CG2 4.25Å; L473-V478 WeakPolarHBondContact O-CB 3.26Å; L473-V478 WeakPolarHBondContact O-CG2 3.35Å; L473-V478 PolarHBondContact O-N 2.86Å; L473-V478 VanDerWaalsContact O-N 3.15Å
479S93.7Very high93.3Very high11 Ų1122.6 Ų22.68%0.07713%0.127CC..  trans-66.6136.5-173.8-179.80000112.7D172 G477 H481D172-S479 VanDerWaalsContact CG-CB 3.46Å; D172-S479 VanDerWaalsContact CG-OG 3.28Å; D172-S479 WeakPolarHBondContact OD1-CB 3.43Å; D172-S479 PolarHBondContact OD1-OG 3.32Å; D172-S479 WeakPolarHBondContact OD2-CB 3.12Å; D172-S479 PolarHBondContact OD2-OG 3Å; G477-S479 PolarHBondContact O-N 2.78Å; S479-H481 VanDerWaalsContact C-N 3.29Å; S479-H481 PolarHBondContact OG-N 3.14Å
480V95.5Very high93.3Very high11 Ų1122.5 Ų22.57%0.06713%0.127CC..SBendtrans-82.4-8.6170.7-61.10000112.8L458 L474 L506 A511L458-V480 HydrophobicContact CD2-CG1 4.03Å; L474-V480 HydrophobicContact CD2-CG1 3.44Å; L474-V480 VanDerWaalsContact CD2-CG1 3.44Å; V480-L506 HydrophobicContact CG1-CD2 3.9Å; V480-A511 HydrophobicContact CB-CB 3.88Å; V480-A511 HydrophobicContact CG2-CB 4.05Å
481H94.6Very high93.4Very high27 Ų2722.5 Ų22.513%0.12513%0.127CC..SBendtrans-103.3-14.2-172.3-58.5-57.4000113.9G138 S479 K483 G510 H512G138-H481 PolarHBondContact O-CD2 3.41Å; S479-H481 VanDerWaalsContact C-N 3.29Å; S479-H481 PolarHBondContact OG-N 3.14Å; H481-K483 PolarHBondContact O-N 3.02Å; H481-G510 PolarHBondContact CE1-O 3.28Å; H481-H512 AromaticContact CE1-CE1 3.39Å; H481-H512 PolarHBondContact CE1-CE1 3.34Å; H481-H512 AromaticContact CE1-ND1 3.5Å; H481-H512 PolarHBondContact CE1-ND1 3.1Å; H481-H512 AromaticContact ND1-CE1 3.21Å; H481-H512 PolarHBondContact ND1-CE1 3.02Å; H481-H512 AromaticContact ND1-ND1 3.66Å
482T93.4Very high93.4Very high15 Ų1519.2 Ų19.29%0.09211%0.111CC..  trans-57.8131.2179.3-55.10000110.4D172 V450 T456 H459D172-T482 PolarHBondContact OD2-OG1 2.85Å; V450-T482 HydrophobicContact CG1-CG2 4.32Å; T456-T482 HydrophobicContact CG2-CG2 3.73Å; H459-T482 PolarHBondContact CE1-O 3.39Å; H459-T482 PolarHBondContact NE2-O 2.98Å
483K93.3Very high93.4Very high28 Ų2819 Ų1912%0.12211%0.111CC..  trans-105.4135.9175.7-60.4178.5-175.41760111D112 H481 S488 T489D112-K483 WeakPolarHBondContact OD1-CE 3.48Å; D112-K483 IonicContact OD1-NZ 3.09Å; D112-K483 PolarHBondContact OD1-NZ 3.08Å; D112-K483 IonicContact OD2-NZ 3.94Å; D112-K483 PolarHBondContact OD2-NZ 3.25Å; H481-K483 PolarHBondContact O-N 3.02Å; K483-S488 CarbonylContact C-O 3.51Å; K483-S488 VanDerWaalsContact CA-O 3.28Å; K483-S488 WeakPolarHBondContact CA-O 3.36Å; K483-T489 HydrophobicContact CG-CG2 3.86Å
484D92.6Very high93.6Very high0 Ų019 Ų190%011%0.111CC..  trans-75.2-177.8172.279-1000112.4R74 M453 R455 S486 N487 S488R74-D484 PolarHBondContact NH2-O 2.95Å; M453-D484 WeakPolarHBondContact O-CB 3.42Å; R455-D484 HydrophobicContact CG-CB 3.57Å; R455-D484 IonicContact CZ-OD2 3.23Å; R455-D484 IonicContact NE-OD2 2.78Å; R455-D484 PolarHBondContact NE-OD2 3.07Å; R455-D484 IonicContact NH2-OD2 2.67Å; R455-D484 PolarHBondContact NH2-OD2 2.91Å; D484-S486 PolarHBondContact O-N 3.4Å; D484-S486 VanDerWaalsContact O-N 3.1Å; D484-S486 VanDerWaalsContact OD1-C 3.31Å; D484-S486 VanDerWaalsContact OD1-CA 3.27Å; D484-S486 WeakPolarHBondContact OD1-CA 3.28Å; D484-S486 WeakPolarHBondContact OD1-CB 3.44Å; D484-S486 PolarHBondContact OD1-N 3.46Å; D484-N487 PolarHBondContact O-N 3.04Å; D484-N487 PolarHBondContact OD1-N 2.92Å; D484-S488 VanDerWaalsContact CG-CB 3.5Å; D484-S488 PolarHBondContact N-O 2.96Å; D484-S488 WeakPolarHBondContact OD1-CA 3.5Å; D484-S488 VanDerWaalsContact OD1-CB 3.25Å; D484-S488 WeakPolarHBondContact OD1-CB 3.16Å; D484-S488 PolarHBondContact OD1-N 3.44Å; D484-S488 WeakPolarHBondContact OD2-CB 3.33Å
485N90.2Very high93.7Very high51 Ų5118.5 Ų18.527%0.27311%0.108SC..THydrogen-bonded Turntrans-68.41.6176.7-74.3-17.8000114.2L8 N73 Y452 M453 R454L8-N485 VanDerWaalsContact CD2-O 3.25Å; L8-N485 WeakPolarHBondContact CD2-O 3.11Å; N73-N485 PolarHBondContact ND2-OD1 2.97Å; Y452-N485 PolarHBondContact O-ND2 2.56Å; Y452-N485 VanDerWaalsContact O-ND2 3.14Å; M453-N485 WeakPolarHBondContact O-CB 3.42Å; M453-N485 PolarHBondContact O-N 2.86Å; R454-N485 WeakPolarHBondContact CD-OD1 3.23Å; R454-N485 WeakPolarHBondContact CG-OD1 3.26Å
486S89.3Confident93.8Very high75 Ų7522.5 Ų22.552%0.52412%0.116SC..THydrogen-bonded Turntrans-118.315.6176-60.30000112.3D484 S488D484-S486 PolarHBondContact O-N 3.4Å; D484-S486 VanDerWaalsContact O-N 3.1Å; D484-S486 VanDerWaalsContact OD1-C 3.31Å; D484-S486 VanDerWaalsContact OD1-CA 3.27Å; D484-S486 WeakPolarHBondContact OD1-CA 3.28Å; D484-S486 WeakPolarHBondContact OD1-CB 3.44Å; D484-S486 PolarHBondContact OD1-N 3.46Å; S486-S488 PolarHBondContact O-N 2.98Å
487N89Confident94Very high42 Ų4221.8 Ų21.823%0.22512%0.12CC..SBendtrans60.915.9-172-63.4-15.9000114.5K7 L8 R74 D484K7-N487 PolarHBondContact O-ND2 3.16Å; L8-N487 WeakPolarHBondContact CD2-OD1 3.41Å; R74-N487 PolarHBondContact NH1-OD1 3.13Å; R74-N487 PolarHBondContact NH2-OD1 2.87Å; D484-N487 PolarHBondContact O-N 3.04Å; D484-N487 PolarHBondContact OD1-N 2.92Å
488S92.6Very high94.3Very high0 Ų025 Ų250%013%0.133CC..  trans-79.6137.8177.3-1500000110.5H459 K483 D484 S486 E493 R496H459-S488 PolarHBondContact NE2-O 2.98Å; H459-S488 VanDerWaalsContact NE2-O 3.1Å; K483-S488 CarbonylContact C-O 3.51Å; K483-S488 VanDerWaalsContact CA-O 3.28Å; K483-S488 WeakPolarHBondContact CA-O 3.36Å; D484-S488 VanDerWaalsContact CG-CB 3.5Å; D484-S488 PolarHBondContact N-O 2.96Å; D484-S488 WeakPolarHBondContact OD1-CA 3.5Å; D484-S488 VanDerWaalsContact OD1-CB 3.25Å; D484-S488 WeakPolarHBondContact OD1-CB 3.16Å; D484-S488 PolarHBondContact OD1-N 3.44Å; D484-S488 WeakPolarHBondContact OD2-CB 3.33Å; S486-S488 PolarHBondContact O-N 2.98Å; S488-E493 WeakPolarHBondContact CB-OE1 3.39Å; S488-E493 PolarHBondContact OG-OE1 2.93Å; S488-R496 PolarHBondContact OG-NH1 3.45Å
489T95.5Very high94.5Very high3 Ų327.3 Ų27.32%0.01814%0.143CC..  trans-105.4165.7169.5610000109.3K483 L491 L492 E493K483-T489 HydrophobicContact CG-CG2 3.86Å; T489-L491 PolarHBondContact O-N 3.37Å; T489-L491 VanDerWaalsContact O-N 3.14Å; T489-L492 PolarHBondContact O-N 3.04Å; T489-L492 PolarHBondContact OG1-N 3.01Å; T489-E493 PolarHBondContact O-N 2.9Å; T489-E493 VanDerWaalsContact O-N 3.1Å
490P97Very high94.7Very high0 Ų029.1 Ų29.10%015%0.151CC..Hα-helixtrans-55.3-32.3172.5-25.735000113.3L458 A462 E493 A494 L506L458-P490 HydrophobicContact CB-CB 4.4Å; L458-P490 HydrophobicContact CB-CG 4.15Å; L458-P490 HydrophobicContact CD2-CB 4.06Å; L458-P490 HydrophobicContact CD2-CG 3.96Å; L458-P490 HydrophobicContact CG-CB 3.81Å; L458-P490 HydrophobicContact CG-CG 3.97Å; A462-P490 HydrophobicContact CB-CB 4.28Å; A462-P490 VanDerWaalsContact CB-O 3.26Å; A462-P490 WeakPolarHBondContact CB-O 3.16Å; P490-E493 PolarHBondContact O-N 2.9Å; P490-A494 PolarHBondContact O-N 2.92Å; P490-L506 HydrophobicContact CB-CD1 4.3Å
491L97.8Very high94.8Very high0 Ų031.3 Ų31.30%017%0.171CC..Hα-helixtrans-64.5-43.2175-179.563.3000111.8T489 E493 A494 I495 V503 L506 R507 A511 L513 A542T489-L491 PolarHBondContact O-N 3.37Å; T489-L491 VanDerWaalsContact O-N 3.14Å; L491-E493 VanDerWaalsContact C-N 3.34Å; L491-A494 PolarHBondContact O-N 3.09Å; L491-I495 HydrophobicContact CD1-CD1 4.41Å; L491-I495 HydrophobicContact CG-CD1 4.07Å; L491-I495 VanDerWaalsContact O-CG1 3.25Å; L491-I495 WeakPolarHBondContact O-CG1 3.5Å; L491-I495 PolarHBondContact O-N 3.18Å; L491-V503 HydrophobicContact CD1-CB 4.4Å; L491-V503 HydrophobicContact CD1-CG1 3.96Å; L491-L506 HydrophobicContact CB-CD1 4.34Å; L491-L506 HydrophobicContact CD1-CB 4.11Å; L491-L506 HydrophobicContact CD1-CD1 4.41Å; L491-R507 HydrophobicContact CD1-CG 4.43Å; L491-A511 HydrophobicContact CB-CB 4.15Å; L491-A511 HydrophobicContact CD2-CB 4.06Å; L491-L513 HydrophobicContact CD2-CB 4.48Å; L491-L513 HydrophobicContact CD2-CD1 4.48Å; L491-A542 HydrophobicContact CD1-CB 4.38Å
492L96.5Very high94.9Very high8 Ų830.2 Ų30.24%0.04217%0.165CC..Hα-helixtrans-65.6-36.6176.7-74.2170.9000112.2T489 I495 R496 L513 W539T489-L492 PolarHBondContact O-N 3.04Å; T489-L492 PolarHBondContact OG1-N 3.01Å; L492-I495 HydrophobicContact CD2-CD1 4.45Å; L492-I495 PolarHBondContact O-N 3.49Å; L492-R496 VanDerWaalsContact O-CG 3.3Å; L492-R496 WeakPolarHBondContact O-CG 3.3Å; L492-R496 PolarHBondContact O-N 3.3Å; L492-L513 HydrophobicContact CD2-CD1 3.81Å; L492-W539 HydrophobicContact CD2-CH2 4.09Å; L492-W539 HydrophobicContact CD2-CZ3 4.13Å
493E96.4Very high95.2Very high16 Ų1629.5 Ų29.58%0.07516%0.161CC..Hα-helixtrans-64.7-42.2173.6-61.1-62.5117.400111.6R455 H459 A462 A463 S488 T489 P490 L491 I495 R496 G497R455-E493 IonicContact CZ-OE1 3.88Å; R455-E493 IonicContact CZ-OE2 3.32Å; R455-E493 IonicContact NH1-OE2 3.12Å; R455-E493 PolarHBondContact NH1-OE2 3.23Å; R455-E493 IonicContact NH2-OE1 2.8Å; R455-E493 PolarHBondContact NH2-OE1 3.2Å; R455-E493 IonicContact NH2-OE2 2.85Å; R455-E493 PolarHBondContact NH2-OE2 3.38Å; R455-E493 VanDerWaalsContact NH2-OE2 3.09Å; H459-E493 HydrophobicContact CB-CG 4.39Å; A462-E493 HydrophobicContact CB-CB 4.34Å; A463-E493 HydrophobicContact CB-CB 4.09Å; S488-E493 WeakPolarHBondContact CB-OE1 3.39Å; S488-E493 PolarHBondContact OG-OE1 2.93Å; T489-E493 PolarHBondContact O-N 2.9Å; T489-E493 VanDerWaalsContact O-N 3.1Å; P490-E493 PolarHBondContact O-N 2.9Å; L491-E493 VanDerWaalsContact C-N 3.34Å; E493-I495 PolarHBondContact O-N 2.93Å; E493-R496 PolarHBondContact O-N 3.28Å; E493-R496 IonicContact OE1-NH1 3.49Å; E493-R496 PolarHBondContact OE1-NH1 2.96Å; E493-G497 PolarHBondContact O-N 3.32Å
494A97.7Very high95.3Very high0 Ų032.2 Ų32.20%017%0.174CC..Hα-helixtrans-62.7-40175.700000112.6A462 P490 L491 G497 H498 H499 I502 V503 L506A462-A494 HydrophobicContact CB-CB 4.18Å; P490-A494 PolarHBondContact O-N 2.92Å; L491-A494 PolarHBondContact O-N 3.09Å; A494-G497 PolarHBondContact O-N 3.15Å; A494-H498 PolarHBondContact O-N 3.01Å; A494-H499 PolarHBondContact O-N 3.43Å; A494-I502 HydrophobicContact CB-CB 4.27Å; A494-I502 HydrophobicContact CB-CG2 3.65Å; A494-V503 HydrophobicContact CB-CG2 3.77Å; A494-L506 HydrophobicContact CB-CD1 4.08Å
495I97Very high95.5Very high1 Ų133.4 Ų33.41%0.00518%0.18CC..Hα-helixtrans-64.6-45.9176.9-67.6163.5000110.7L491 L492 E493 G497 H498 V503 L513 W539 A542L491-I495 HydrophobicContact CD1-CD1 4.41Å; L491-I495 HydrophobicContact CG-CD1 4.07Å; L491-I495 VanDerWaalsContact O-CG1 3.25Å; L491-I495 WeakPolarHBondContact O-CG1 3.5Å; L491-I495 PolarHBondContact O-N 3.18Å; L492-I495 HydrophobicContact CD2-CD1 4.45Å; L492-I495 PolarHBondContact O-N 3.49Å; E493-I495 PolarHBondContact O-N 2.93Å; I495-G497 VanDerWaalsContact C-N 3.25Å; I495-G497 PolarHBondContact O-N 2.94Å; I495-H498 PolarHBondContact O-N 3.14Å; I495-H498 VanDerWaalsContact O-N 3.08Å; I495-V503 HydrophobicContact CG1-CG1 4.46Å; I495-V503 HydrophobicContact CG1-CG2 3.86Å; I495-L513 HydrophobicContact CD1-CD1 3.58Å; I495-W539 HydrophobicContact CD1-CE3 4.15Å; I495-W539 HydrophobicContact CD1-CZ3 4.15Å; I495-W539 HydrophobicContact CG2-CD2 3.58Å; I495-W539 HydrophobicContact CG2-CE3 3.85Å; I495-W539 HydrophobicContact CG2-CG 4.11Å; I495-W539 HydrophobicContact CG2-CH2 4.01Å; I495-W539 HydrophobicContact CG2-CZ2 3.73Å; I495-W539 HydrophobicContact CG2-CZ3 4.08Å; I495-A542 HydrophobicContact CD1-CB 3.45Å; I495-A542 VanDerWaalsContact CD1-CB 3.45Å; I495-A542 HydrophobicContact CG1-CB 4Å
496R94.6Very high95.9Very high132 Ų13231 Ų3150%0.49817%0.167SC..Hα-helixtrans-64.1-30.3178-72.5173.6-173.81534.4112.9S488 L492 E493 H498S488-R496 PolarHBondContact OG-NH1 3.45Å; L492-R496 VanDerWaalsContact O-CG 3.3Å; L492-R496 WeakPolarHBondContact O-CG 3.3Å; L492-R496 PolarHBondContact O-N 3.3Å; E493-R496 PolarHBondContact O-N 3.28Å; E493-R496 IonicContact OE1-NH1 3.49Å; E493-R496 PolarHBondContact OE1-NH1 2.96Å; R496-H498 VanDerWaalsContact C-N 3.32Å
497G95.1Very high96.2Very high26 Ų2627.9 Ų27.927%0.26814%0.144SC..THydrogen-bonded Turntrans-84.6-0.8174.500000114.7E493 A494 I495 H499E493-G497 PolarHBondContact O-N 3.32Å; A494-G497 PolarHBondContact O-N 3.15Å; I495-G497 VanDerWaalsContact C-N 3.25Å; I495-G497 PolarHBondContact O-N 2.94Å; G497-H499 PolarHBondContact O-CE1 3.34Å; G497-H499 PolarHBondContact O-N 3.12Å; G497-H499 PolarHBondContact O-NE2 2.98Å
498H95.7Very high96.4Very high75 Ų7532.4 Ų32.435%0.34716%0.162SC..THydrogen-bonded Turntrans5926.9-175.3-45.4-65.4000114.8A494 I495 R496 I500 D532 D534 S535 S538A494-H498 PolarHBondContact O-N 3.01Å; I495-H498 PolarHBondContact O-N 3.14Å; I495-H498 VanDerWaalsContact O-N 3.08Å; R496-H498 VanDerWaalsContact C-N 3.32Å; H498-I500 PolarHBondContact O-N 3.2Å; H498-D532 IonicContact CE1-OD2 3.8Å; H498-D534 HydrophobicContact CB-CB 4.45Å; H498-S535 WeakPolarHBondContact ND1-CA 3.47Å; H498-S535 PolarHBondContact ND1-N 3.44Å; H498-S538 WeakPolarHBondContact CA-OG 3.45Å
499H97.3Very high96.5Very high53 Ų5333.1 Ų33.125%0.24517%0.167CC..  trans-8671.1-175.3-60.5-56.8000111.7A462 A463 G465 A494 G497 A501 I502 V503A462-H499 PolarHBondContact O-CD2 2.88Å; A463-H499 PolarHBondContact O-NE2 3Å; A463-H499 VanDerWaalsContact O-NE2 3.17Å; G465-H499 WeakPolarHBondContact CA-CE1 3.45Å; G465-H499 WeakPolarHBondContact CA-ND1 3.39Å; G465-H499 VanDerWaalsContact CA-NE2 3.34Å; G465-H499 WeakPolarHBondContact CA-NE2 3.28Å; G465-H499 PolarHBondContact N-NE2 2.9Å; A494-H499 PolarHBondContact O-N 3.43Å; G497-H499 PolarHBondContact O-CE1 3.34Å; G497-H499 PolarHBondContact O-N 3.12Å; G497-H499 PolarHBondContact O-NE2 2.98Å; H499-A501 VanDerWaalsContact C-N 3.3Å; H499-A501 PolarHBondContact O-N 2.89Å; H499-I502 HydrophobicContact CB-CB 4.03Å; H499-I502 HydrophobicContact CB-CD1 4Å; H499-I502 HydrophobicContact CB-CG1 4.3Å; H499-I502 WeakPolarHBondContact O-CA 3.3Å; H499-I502 WeakPolarHBondContact O-CB 3.35Å; H499-I502 PolarHBondContact O-N 3.49Å; H499-V503 PolarHBondContact O-N 3.2Å
500I96.9Very high96.5Very high49 Ų4933.6 Ų33.625%0.25117%0.172SC..Hα-helixtrans-52-44-172.6-63.6173.5000112.7H498 I502 V503 E504 K537H498-I500 PolarHBondContact O-N 3.2Å; I500-I502 VanDerWaalsContact C-N 3.26Å; I500-I502 PolarHBondContact O-N 3.17Å; I500-V503 WeakPolarHBondContact O-CB 3.35Å; I500-V503 PolarHBondContact O-N 3.45Å; I500-V503 VanDerWaalsContact O-N 3.14Å; I500-E504 HydrophobicContact CG2-CG 4.43Å; I500-E504 WeakPolarHBondContact O-CG 3.27Å; I500-E504 PolarHBondContact O-N 3.25Å; I500-K537 HydrophobicContact CD1-CB 3.89Å
501A97.7Very high96.4Very high57 Ų5733.6 Ų33.647%0.47117%0.173SC..Hα-helixtrans-61-34.6178.800000112.9L467 H499 L505L467-A501 HydrophobicContact CD2-CB 4.43Å; H499-A501 VanDerWaalsContact C-N 3.3Å; H499-A501 PolarHBondContact O-N 2.89Å; A501-L505 WeakPolarHBondContact O-CB 3.32Å; A501-L505 PolarHBondContact O-N 3.16Å; A501-L505 VanDerWaalsContact O-N 3.16Å
502I98.2Very high96.2Very high3 Ų334.1 Ų34.12%0.01518%0.175CC..Hα-helixtrans-75.4-41175.4-68173.9000110.4A462 G465 L467 V470 A494 H499 I500 E504 L505 L506A462-I502 HydrophobicContact CB-CG2 4.25Å; G465-I502 VanDerWaalsContact C-CD1 3.41Å; L467-I502 HydrophobicContact CB-CG1 4.35Å; L467-I502 HydrophobicContact CD1-CG1 3.83Å; V470-I502 HydrophobicContact CG1-CG2 4.27Å; V470-I502 HydrophobicContact CG2-CD1 4.02Å; V470-I502 HydrophobicContact CG2-CG1 4.31Å; V470-I502 HydrophobicContact CG2-CG2 4.09Å; A494-I502 HydrophobicContact CB-CB 4.27Å; A494-I502 HydrophobicContact CB-CG2 3.65Å; H499-I502 HydrophobicContact CB-CB 4.03Å; H499-I502 HydrophobicContact CB-CD1 4Å; H499-I502 HydrophobicContact CB-CG1 4.3Å; H499-I502 WeakPolarHBondContact O-CA 3.3Å; H499-I502 WeakPolarHBondContact O-CB 3.35Å; H499-I502 PolarHBondContact O-N 3.49Å; I500-I502 VanDerWaalsContact C-N 3.26Å; I500-I502 PolarHBondContact O-N 3.17Å; I502-E504 VanDerWaalsContact C-N 3.33Å; I502-E504 PolarHBondContact O-N 3.15Å; I502-L505 PolarHBondContact O-N 3.05Å; I502-L506 HydrophobicContact CG2-CD1 3.76Å; I502-L506 HydrophobicContact CG2-CG 4.11Å; I502-L506 WeakPolarHBondContact O-CB 3.45Å; I502-L506 VanDerWaalsContact O-CG 3.3Å; I502-L506 WeakPolarHBondContact O-CG 3.34Å; I502-L506 PolarHBondContact O-N 3.47Å
503V98.1Very high96Very high0 Ų035.2 Ų35.20%018%0.18CC..Hα-helixtrans-54.5-50.4174.7171.70000110.4L491 A494 I495 H499 I500 L505 L506 R507 A542L491-V503 HydrophobicContact CD1-CB 4.4Å; L491-V503 HydrophobicContact CD1-CG1 3.96Å; A494-V503 HydrophobicContact CB-CG2 3.77Å; I495-V503 HydrophobicContact CG1-CG1 4.46Å; I495-V503 HydrophobicContact CG1-CG2 3.86Å; H499-V503 PolarHBondContact O-N 3.2Å; I500-V503 WeakPolarHBondContact O-CB 3.35Å; I500-V503 PolarHBondContact O-N 3.45Å; I500-V503 VanDerWaalsContact O-N 3.14Å; V503-L505 PolarHBondContact O-N 2.91Å; V503-L506 PolarHBondContact O-N 3.3Å; V503-R507 WeakPolarHBondContact O-CG 3.48Å; V503-R507 PolarHBondContact O-N 3.06Å; V503-A542 HydrophobicContact CG1-CB 3.75Å
504E97Very high95.5Very high86 Ų8636 Ų3640%0.40219%0.187SC..Hα-helixtrans-62.7-41.4178-69.9180-176.800112.6I500 I502 R507 K508I500-E504 HydrophobicContact CG2-CG 4.43Å; I500-E504 WeakPolarHBondContact O-CG 3.27Å; I500-E504 PolarHBondContact O-N 3.25Å; I502-E504 VanDerWaalsContact C-N 3.33Å; I502-E504 PolarHBondContact O-N 3.15Å; E504-R507 PolarHBondContact O-N 3.48Å; E504-K508 WeakPolarHBondContact O-CB 3.41Å; E504-K508 VanDerWaalsContact O-CG 3.28Å; E504-K508 WeakPolarHBondContact O-CG 3.46Å; E504-K508 PolarHBondContact O-N 3.28Å
505L96.9Very high95Very high24 Ų2438.1 Ų38.113%0.12620%0.197CC..Hα-helixtrans-64-42.8177.7176.861.5000112L467 V470 Q471 L474 A501 I502 V503 K508 S509L467-L505 HydrophobicContact CD1-CD2 3.76Å; V470-L505 HydrophobicContact CB-CD2 4.48Å; V470-L505 HydrophobicContact CG1-CD2 3.71Å; V470-L505 HydrophobicContact CG1-CG 4.49Å; Q471-L505 HydrophobicContact CG-CD2 3.51Å; L474-L505 HydrophobicContact CD1-CD1 4.42Å; L474-L505 HydrophobicContact CD1-CD2 4.1Å; L474-L505 HydrophobicContact CD1-CG 3.93Å; A501-L505 WeakPolarHBondContact O-CB 3.32Å; A501-L505 PolarHBondContact O-N 3.16Å; A501-L505 VanDerWaalsContact O-N 3.16Å; I502-L505 PolarHBondContact O-N 3.05Å; V503-L505 PolarHBondContact O-N 2.91Å; L505-K508 PolarHBondContact O-N 2.91Å; L505-S509 WeakPolarHBondContact O-CB 3.44Å; L505-S509 PolarHBondContact O-N 2.93Å; L505-S509 PolarHBondContact O-OG 3.14Å
506L97.3Very high94.4Very high0 Ų042 Ų420%022%0.216CC..Hα-helixtrans-66.1-44177.8-71.2174000111L458 A462 V470 L474 V480 P490 L491 A494 I502 V503 K508 S509 G510 A511L458-L506 HydrophobicContact CD1-CD2 4.47Å; L458-L506 HydrophobicContact CD2-CD2 4.12Å; L458-L506 HydrophobicContact CG-CD2 4.48Å; A462-L506 HydrophobicContact CB-CD1 4.47Å; V470-L506 HydrophobicContact CG1-CD2 4.34Å; L474-L506 HydrophobicContact CD1-CD2 4.36Å; L474-L506 HydrophobicContact CD2-CD2 4.28Å; V480-L506 HydrophobicContact CG1-CD2 3.9Å; P490-L506 HydrophobicContact CB-CD1 4.3Å; L491-L506 HydrophobicContact CB-CD1 4.34Å; L491-L506 HydrophobicContact CD1-CB 4.11Å; L491-L506 HydrophobicContact CD1-CD1 4.41Å; A494-L506 HydrophobicContact CB-CD1 4.08Å; I502-L506 HydrophobicContact CG2-CD1 3.76Å; I502-L506 HydrophobicContact CG2-CG 4.11Å; I502-L506 WeakPolarHBondContact O-CB 3.45Å; I502-L506 VanDerWaalsContact O-CG 3.3Å; I502-L506 WeakPolarHBondContact O-CG 3.34Å; I502-L506 PolarHBondContact O-N 3.47Å; V503-L506 PolarHBondContact O-N 3.3Å; L506-K508 PolarHBondContact O-N 3.14Å; L506-S509 CarbonylContact O-C 3.58Å; L506-S509 WeakPolarHBondContact O-CA 3.49Å; L506-S509 PolarHBondContact O-N 3.47Å; L506-G510 PolarHBondContact O-N 2.95Å; L506-A511 VanDerWaalsContact C-CB 3.49Å; L506-A511 HydrophobicContact CB-CB 3.85Å; L506-A511 WeakPolarHBondContact O-CB 3.31Å; L506-A511 PolarHBondContact O-N 3.1Å
507R95.8Very high94Very high10 Ų1039.8 Ų39.84%0.03822%0.218CC..Hα-helixtrans-58.6-44.9173.6-74-63.6-55.5179.823.5111.9E109 K231 L491 V503 E504 S509 G510 A511 H512 A542 E543E109-R507 IonicContact OE1-NH2 3.87Å; E109-R507 PolarHBondContact OE1-NH2 3.14Å; E109-R507 IonicContact OE2-NH2 2.86Å; K231-R507 WeakPolarHBondContact CE-O 3.09Å; L491-R507 HydrophobicContact CD1-CG 4.43Å; V503-R507 WeakPolarHBondContact O-CG 3.48Å; V503-R507 PolarHBondContact O-N 3.06Å; E504-R507 PolarHBondContact O-N 3.48Å; R507-S509 PolarHBondContact O-N 2.85Å; R507-G510 PolarHBondContact O-N 3.21Å; R507-G510 VanDerWaalsContact O-N 3.15Å; R507-A511 VanDerWaalsContact CD-O 3.31Å; R507-A511 WeakPolarHBondContact CD-O 3.25Å; R507-A511 PolarHBondContact NE-O 2.75Å; R507-H512 VanDerWaalsContact NH1-CA 3.3Å; R507-A542 PolarHBondContact NH1-O 3.46Å; R507-E543 IonicContact CZ-OE1 2.92Å; R507-E543 IonicContact CZ-OE2 2.97Å; R507-E543 VanDerWaalsContact NE-CD 3.34Å; R507-E543 IonicContact NE-OE1 3.09Å; R507-E543 PolarHBondContact NE-OE1 3.08Å; R507-E543 IonicContact NE-OE2 2.9Å; R507-E543 IonicContact NH2-OE1 3.37Å; R507-E543 PolarHBondContact NH2-OE1 2.77Å; R507-E543 VanDerWaalsContact NH2-OE1 3.09Å; R507-E543 IonicContact NH2-OE2 3.34Å; R507-E543 PolarHBondContact NH2-OE2 2.97Å
508K94.6Very high93.6Very high138 Ų13843.5 Ų43.560%0.623%0.232SC*.Hα-helixtrans-60.4-31.3175.1-75.5171.7-176.7169.90112.3S230 K231 E504 L505 L506 G510S230-K508 CarbonylContact C-O 3.6Å; K231-K508 PolarHBondContact N-O 3.43Å; E504-K508 WeakPolarHBondContact O-CB 3.41Å; E504-K508 VanDerWaalsContact O-CG 3.28Å; E504-K508 WeakPolarHBondContact O-CG 3.46Å; E504-K508 PolarHBondContact O-N 3.28Å; L505-K508 PolarHBondContact O-N 2.91Å; L506-K508 PolarHBondContact O-N 3.14Å; K508-G510 VanDerWaalsContact C-N 3.32Å; K508-G510 PolarHBondContact O-N 3.16Å
509S94.5Very high93.3Very high14 Ų1442.8 Ų42.810%0.09823%0.23CC..THydrogen-bonded Turntrans-89.214.3179.1-49.90000113.9S230 L505 L506 R507S230-S509 CarbonylContact O-C 3.51Å; L505-S509 WeakPolarHBondContact O-CB 3.44Å; L505-S509 PolarHBondContact O-N 2.93Å; L505-S509 PolarHBondContact O-OG 3.14Å; L506-S509 CarbonylContact O-C 3.58Å; L506-S509 WeakPolarHBondContact O-CA 3.49Å; L506-S509 PolarHBondContact O-N 3.47Å; R507-S509 PolarHBondContact O-N 2.85Å
510G93.9Very high93.1Very high13 Ų1340.7 Ų40.713%0.13422%0.221CC..THydrogen-bonded Turntrans97.9-7.7175.500000116.2H481 L506 R507 K508 H512H481-G510 PolarHBondContact CE1-O 3.28Å; L506-G510 PolarHBondContact O-N 2.95Å; R507-G510 PolarHBondContact O-N 3.21Å; R507-G510 VanDerWaalsContact O-N 3.15Å; K508-G510 VanDerWaalsContact C-N 3.32Å; K508-G510 PolarHBondContact O-N 3.16Å; G510-H512 PolarHBondContact O-N 2.92Å
511A95.5Very high93Very high1 Ų139 Ų391%0.00821%0.213CC..  trans-61.1140.2178.100000110.2V480 L491 L506 R507V480-A511 HydrophobicContact CB-CB 3.88Å; V480-A511 HydrophobicContact CG2-CB 4.05Å; L491-A511 HydrophobicContact CB-CB 4.15Å; L491-A511 HydrophobicContact CD2-CB 4.06Å; L506-A511 VanDerWaalsContact C-CB 3.49Å; L506-A511 HydrophobicContact CB-CB 3.85Å; L506-A511 WeakPolarHBondContact O-CB 3.31Å; L506-A511 PolarHBondContact O-N 3.1Å; R507-A511 VanDerWaalsContact CD-O 3.31Å; R507-A511 WeakPolarHBondContact CD-O 3.25Å; R507-A511 PolarHBondContact NE-O 2.75Å
512H93.5Very high92.9Very high10 Ų1039 Ų395%0.04621%0.213CC..  trans-132155.8174.754.4-74.8000110.7E109 K139 H481 R507 G510 T514E109-H512 HydrophobicContact CB-CB 4.18Å; E109-H512 HydrophobicContact CG-CB 3.9Å; E109-H512 PolarHBondContact O-CD2 2.79Å; K139-H512 WeakPolarHBondContact CE-CE1 3.15Å; K139-H512 PolarHBondContact NZ-CE1 2.99Å; K139-H512 PolarHBondContact NZ-NE2 3.01Å; H481-H512 AromaticContact CE1-CE1 3.39Å; H481-H512 PolarHBondContact CE1-CE1 3.34Å; H481-H512 AromaticContact CE1-ND1 3.5Å; H481-H512 PolarHBondContact CE1-ND1 3.1Å; H481-H512 AromaticContact ND1-CE1 3.21Å; H481-H512 PolarHBondContact ND1-CE1 3.02Å; H481-H512 AromaticContact ND1-ND1 3.66Å; R507-H512 VanDerWaalsContact NH1-CA 3.3Å; G510-H512 PolarHBondContact O-N 2.92Å; H512-T514 VanDerWaalsContact CD2-CG2 3.47Å; H512-T514 WeakPolarHBondContact CD2-CG2 3.42Å; H512-T514 WeakPolarHBondContact NE2-CG2 3.3Å; H512-T514 PolarHBondContact O-N 3.37Å; H512-T514 VanDerWaalsContact O-N 3.17Å
513L92.6Very high92.7Very high31 Ų3141.6 Ų41.616%0.16223%0.227CC..  trans-82.297.7-172.1-171.865.9000110.5L491 L492 I495 I515 W539 A542 A544L491-L513 HydrophobicContact CD2-CB 4.48Å; L491-L513 HydrophobicContact CD2-CD1 4.48Å; L492-L513 HydrophobicContact CD2-CD1 3.81Å; I495-L513 HydrophobicContact CD1-CD1 3.58Å; L513-I515 HydrophobicContact CD1-CG2 4.45Å; L513-I515 HydrophobicContact CD2-CG2 3.97Å; L513-I515 HydrophobicContact CG-CG2 3.82Å; L513-I515 PolarHBondContact O-N 3.43Å; L513-W539 HydrophobicContact CD1-CE3 4.41Å; L513-W539 HydrophobicContact CD1-CZ3 3.98Å; L513-W539 HydrophobicContact CD2-CE3 4.16Å; L513-W539 HydrophobicContact CD2-CZ3 4.29Å; L513-A542 HydrophobicContact CD1-CB 4.48Å; L513-A544 HydrophobicContact CD2-CB 3.56Å
514T85.1Confident92.6Very high34 Ų3441.6 Ų41.621%0.20923%0.227CC..  trans-9386.217558.60000110.5H512H512-T514 VanDerWaalsContact CD2-CG2 3.47Å; H512-T514 WeakPolarHBondContact CD2-CG2 3.42Å; H512-T514 WeakPolarHBondContact NE2-CG2 3.3Å; H512-T514 PolarHBondContact O-N 3.37Å; H512-T514 VanDerWaalsContact O-N 3.17Å
515I87.7Confident92.6Very high43 Ų4338.9 Ų38.922%0.22122%0.219CC..  trans-134.7141176.3-169.5166.1000109.9L513 N519 L520 W539L513-I515 HydrophobicContact CD1-CG2 4.45Å; L513-I515 HydrophobicContact CD2-CG2 3.97Å; L513-I515 HydrophobicContact CG-CG2 3.82Å; L513-I515 PolarHBondContact O-N 3.43Å; I515-N519 HydrophobicContact CD1-CB 4.11Å; I515-N519 HydrophobicContact CG1-CB 3.82Å; I515-L520 HydrophobicContact CD1-CB 4.21Å; I515-L520 HydrophobicContact CG1-CB 4.33Å; I515-L520 HydrophobicContact CG2-CB 3.84Å; I515-L520 HydrophobicContact CG2-CD1 4.33Å; I515-L520 HydrophobicContact CG2-CD2 4.21Å; I515-L520 HydrophobicContact CG2-CG 4.35Å; I515-W539 HydrophobicContact CD1-CH2 3.71Å; I515-W539 HydrophobicContact CD1-CZ3 3.87Å
516E84.7Confident92.5Very high83 Ų8344.1 Ų44.139%0.38825%0.245SC..  trans-66.7140.8173.8-64-177.3140.900110.3L518 N519 L520E516-L518 PolarHBondContact O-N 3.35Å; E516-L518 VanDerWaalsContact O-N 3.16Å; E516-N519 HydrophobicContact CB-CB 4.4Å; E516-N519 WeakPolarHBondContact O-CA 3.37Å; E516-N519 PolarHBondContact O-N 3.46Å; E516-N519 PolarHBondContact OE2-ND2 3.47Å; E516-L520 PolarHBondContact O-N 3Å
517P86.5Confident92.5Very high85 Ų8544.3 Ų44.355%0.55225%0.246SC*.Hα-helixtrans-52.1-41-178.8-29.435.5000113.8N519 L520 C521 V548P517-N519 PolarHBondContact O-N 3.34Å; P517-L520 PolarHBondContact O-N 3.3Å; P517-C521 WeakPolarHBondContact O-CB 3.46Å; P517-C521 PolarHBondContact O-N 3.24Å; P517-V548 HydrophobicContact CB-CG1 4.07Å; P517-V548 WeakPolarHBondContact O-CG1 3.34Å
518L87Confident92.6Very high105 Ų10543.8 Ų43.855%0.5524%0.244SC..Hα-helixtrans-65.6-36.5177.4-68.6173.7000112.9E516 C521 A522E516-L518 PolarHBondContact O-N 3.35Å; E516-L518 VanDerWaalsContact O-N 3.16Å; L518-C521 PolarHBondContact O-SG 3.5Å; L518-A522 WeakPolarHBondContact O-CB 3.3Å; L518-A522 PolarHBondContact O-N 3.36Å; L518-A522 VanDerWaalsContact O-N 3.16Å
519N89.3Confident92.7Very high59 Ų5939.3 Ų39.332%0.31623%0.232SC..Hα-helixtrans-71.9-38.8175.3-71.2-38.1000110.7I515 E516 P517 A522 N523I515-N519 HydrophobicContact CD1-CB 4.11Å; I515-N519 HydrophobicContact CG1-CB 3.82Å; E516-N519 HydrophobicContact CB-CB 4.4Å; E516-N519 WeakPolarHBondContact O-CA 3.37Å; E516-N519 PolarHBondContact O-N 3.46Å; E516-N519 PolarHBondContact OE2-ND2 3.47Å; P517-N519 PolarHBondContact O-N 3.34Å; N519-A522 PolarHBondContact O-N 3.05Å; N519-N523 PolarHBondContact O-N 3.09Å; N519-N523 VanDerWaalsContact O-N 3.1Å; N519-N523 PolarHBondContact O-ND2 2.88Å
520L93.4Very high92.7Very high10 Ų1042.2 Ų42.25%0.05225%0.253CS..Hα-helixtrans-62.3-48.8174.8-179.357.4000111I515 E516 P517 A522 N523 L524 W539 A544 V548I515-L520 HydrophobicContact CD1-CB 4.21Å; I515-L520 HydrophobicContact CG1-CB 4.33Å; I515-L520 HydrophobicContact CG2-CB 3.84Å; I515-L520 HydrophobicContact CG2-CD1 4.33Å; I515-L520 HydrophobicContact CG2-CD2 4.21Å; I515-L520 HydrophobicContact CG2-CG 4.35Å; E516-L520 PolarHBondContact O-N 3Å; P517-L520 PolarHBondContact O-N 3.3Å; L520-A522 VanDerWaalsContact C-N 3.27Å; L520-A522 PolarHBondContact O-N 3.14Å; L520-N523 PolarHBondContact O-N 3.02Å; L520-N523 VanDerWaalsContact O-N 3.14Å; L520-L524 HydrophobicContact CD1-CD1 4.06Å; L520-L524 HydrophobicContact CD1-CD2 4.26Å; L520-L524 HydrophobicContact CD1-CG 3.93Å; L520-L524 HydrophobicContact CG-CD1 3.93Å; L520-L524 HydrophobicContact CG-CG 4.23Å; L520-L524 VanDerWaalsContact O-CG 3.31Å; L520-L524 WeakPolarHBondContact O-CG 3.44Å; L520-L524 PolarHBondContact O-N 2.93Å; L520-W539 HydrophobicContact CD1-CD2 4.21Å; L520-W539 HydrophobicContact CD1-CE3 3.69Å; L520-W539 HydrophobicContact CD1-CZ3 3.95Å; L520-A544 HydrophobicContact CD1-CB 4.08Å; L520-A544 HydrophobicContact CD2-CB 4.27Å; L520-V548 HydrophobicContact CD2-CG2 4.11Å
521C94.6Very high92.8Very high13 Ų1344 Ų449%0.08826%0.259CS..Hα-helixtrans-60-39.2-179.682.60000111.7P517 L518 L524 A525 V548P517-C521 WeakPolarHBondContact O-CB 3.46Å; P517-C521 PolarHBondContact O-N 3.24Å; L518-C521 PolarHBondContact O-SG 3.5Å; C521-L524 PolarHBondContact O-N 3.16Å; C521-A525 WeakPolarHBondContact O-CB 3.43Å; C521-A525 PolarHBondContact O-N 2.95Å; C521-V548 HydrophobicContact CB-CG1 3.85Å
522A94.3Very high92.8Very high56 Ų5646.4 Ų46.446%0.46327%0.272SS..Hα-helixtrans-63.9-43.117600000112.5L518 N519 L520 M526L518-A522 WeakPolarHBondContact O-CB 3.3Å; L518-A522 PolarHBondContact O-N 3.36Å; L518-A522 VanDerWaalsContact O-N 3.16Å; N519-A522 PolarHBondContact O-N 3.05Å; L520-A522 VanDerWaalsContact C-N 3.27Å; L520-A522 PolarHBondContact O-N 3.14Å; A522-M526 WeakPolarHBondContact O-CB 3.4Å; A522-M526 PolarHBondContact O-N 2.99Å
523N94.7Very high93Very high58 Ų5846.7 Ų46.731%0.3127%0.274SS..Hα-helixtrans-64.5-44.4176-77.6-73.1000111.7N519 L520 M526 A527 W539N519-N523 PolarHBondContact O-N 3.09Å; N519-N523 VanDerWaalsContact O-N 3.1Å; N519-N523 PolarHBondContact O-ND2 2.88Å; L520-N523 PolarHBondContact O-N 3.02Å; L520-N523 VanDerWaalsContact O-N 3.14Å; N523-M526 PolarHBondContact O-N 3.21Å; N523-A527 PolarHBondContact O-N 3.15Å; N523-W539 HydrophobicContact CB-CH2 4.38Å; N523-W539 HydrophobicContact CB-CZ2 3.68Å
524L96.7Very high93.1Very high1 Ų149.5 Ų49.51%0.00529%0.289CS..Hα-helixtrans-66.1-40.7178.6-63.7179000112.1L520 C521 A527 A528 M536 W539 L546 A556L520-L524 HydrophobicContact CD1-CD1 4.06Å; L520-L524 HydrophobicContact CD1-CD2 4.26Å; L520-L524 HydrophobicContact CD1-CG 3.93Å; L520-L524 HydrophobicContact CG-CD1 3.93Å; L520-L524 HydrophobicContact CG-CG 4.23Å; L520-L524 VanDerWaalsContact O-CG 3.31Å; L520-L524 WeakPolarHBondContact O-CG 3.44Å; L520-L524 PolarHBondContact O-N 2.93Å; C521-L524 PolarHBondContact O-N 3.16Å; L524-A527 PolarHBondContact O-N 3.21Å; L524-A528 WeakPolarHBondContact O-CB 3.24Å; L524-A528 PolarHBondContact O-N 3Å; L524-M536 HydrophobicContact CB-CE 4.5Å; L524-M536 HydrophobicContact CD2-CE 4.33Å; L524-M536 HydrophobicContact CD2-SD 3.76Å; L524-W539 HydrophobicContact CD2-CB 3.92Å; L524-W539 HydrophobicContact CD2-CG 3.93Å; L524-L546 HydrophobicContact CD1-CD2 4.18Å; L524-L546 HydrophobicContact CD2-CD2 3.71Å; L524-A556 HydrophobicContact CB-CB 4.02Å
525A96Very high93.6Very high28 Ų2848.6 Ų48.623%0.23128%0.284CS..Hα-helixtrans-63.5-41175.400000111.7C521 A528 A529 V559C521-A525 WeakPolarHBondContact O-CB 3.43Å; C521-A525 PolarHBondContact O-N 2.95Å; A525-A528 PolarHBondContact O-N 3.17Å; A525-A529 WeakPolarHBondContact O-CB 3.35Å; A525-A529 PolarHBondContact O-N 3.1Å; A525-V559 HydrophobicContact CB-CG2 4.05Å
526M96Very high94Very high135 Ų13546.6 Ų46.667%0.66527%0.274SS*.Hα-helixtrans-62.8-49.6176-174.7173.1-67.500111.3A522 N523 A528 A529 S530A522-M526 WeakPolarHBondContact O-CB 3.4Å; A522-M526 PolarHBondContact O-N 2.99Å; N523-M526 PolarHBondContact O-N 3.21Å; M526-A528 VanDerWaalsContact C-N 3.29Å; M526-A528 PolarHBondContact O-N 3.37Å; M526-A529 PolarHBondContact O-N 2.92Å; M526-S530 PolarHBondContact O-N 2.87Å; M526-S530 PolarHBondContact O-OG 2.87Å; M526-S530 VanDerWaalsContact O-OG 3.07Å
527A96.4Very high94.6Very high3 Ų346 Ų463%0.02527%0.27CS..Hα-helixtrans-59.6-40.9176.100000111.8N523 L524 S530 N531 D532 M536N523-A527 PolarHBondContact O-N 3.15Å; L524-A527 PolarHBondContact O-N 3.21Å; A527-S530 PolarHBondContact O-N 3.32Å; A527-S530 PolarHBondContact O-OG 3.38Å; A527-N531 PolarHBondContact O-N 3.17Å; A527-N531 VanDerWaalsContact O-N 3.12Å; A527-D532 HydrophobicContact CB-CB 4.4Å; A527-D532 PolarHBondContact O-N 3.34Å; A527-M536 HydrophobicContact CB-CE 4.11Å
528A97.2Very high95.1Very high0 Ų041.9 Ų41.90%024%0.243CC..Hα-helixtrans-65.8-37.1177.500000113.1L524 A525 M526 M536 A556 V559 A560 N565 M568L524-A528 WeakPolarHBondContact O-CB 3.24Å; L524-A528 PolarHBondContact O-N 3Å; A525-A528 PolarHBondContact O-N 3.17Å; M526-A528 VanDerWaalsContact C-N 3.29Å; M526-A528 PolarHBondContact O-N 3.37Å; A528-M536 HydrophobicContact CB-CE 4.27Å; A528-A556 HydrophobicContact CB-CB 4.15Å; A528-A556 WeakPolarHBondContact CB-O 3.44Å; A528-V559 HydrophobicContact CB-CB 4.27Å; A528-V559 HydrophobicContact CB-CG1 4.34Å; A528-A560 HydrophobicContact CB-CB 4.18Å; A528-N565 PolarHBondContact O-ND2 2.81Å; A528-M568 HydrophobicContact CB-CG 4.23Å
529A96.5Very high95.5Very high43 Ų4337.2 Ų37.236%0.35522%0.218SC..Hα-helixtrans-72.4-37.7177.400000112.5A525 M526 N531 V559 V563 N565A525-A529 WeakPolarHBondContact O-CB 3.35Å; A525-A529 PolarHBondContact O-N 3.1Å; M526-A529 PolarHBondContact O-N 2.92Å; A529-N531 VanDerWaalsContact C-N 3.34Å; A529-V559 HydrophobicContact CB-CG1 3.84Å; A529-V563 HydrophobicContact CB-CG2 4.4Å; A529-N565 PolarHBondContact O-ND2 3.08Å
530S95.8Very high95.9Very high75 Ų7538 Ų3852%0.52422%0.219SC..Hα-helixtrans-86.30.5179.862.30000114.6M526 A527 D532M526-S530 PolarHBondContact O-N 2.87Å; M526-S530 PolarHBondContact O-OG 2.87Å; M526-S530 VanDerWaalsContact O-OG 3.07Å; A527-S530 PolarHBondContact O-N 3.32Å; A527-S530 PolarHBondContact O-OG 3.38Å; S530-D532 PolarHBondContact O-N 3.09Å; S530-D532 WeakPolarHBondContact OG-CB 3.38Å
531N95.6Very high96Very high51 Ų5139.1 Ų39.127%0.27323%0.228SC..THydrogen-bonded Turntrans53.734.6-170.2-160.349.4000112.9A527 A529 L533 N565 M568A527-N531 PolarHBondContact O-N 3.17Å; A527-N531 VanDerWaalsContact O-N 3.12Å; A529-N531 VanDerWaalsContact C-N 3.34Å; N531-L533 PolarHBondContact O-N 2.8Å; N531-L533 VanDerWaalsContact O-N 3.08Å; N531-N565 HydrophobicContact CB-CB 4.17Å; N531-N565 PolarHBondContact N-ND2 3.15Å; N531-M568 WeakPolarHBondContact OD1-CB 3.45Å; N531-M568 PolarHBondContact OD1-N 2.7Å
532D96.1Very high96Very high51 Ų5138.5 Ų38.527%0.27322%0.224SC..  trans-83.285179.9-177.5-6.7000110.3H498 A527 S530 D534 S535 M536H498-D532 IonicContact CE1-OD2 3.8Å; A527-D532 HydrophobicContact CB-CB 4.4Å; A527-D532 PolarHBondContact O-N 3.34Å; S530-D532 PolarHBondContact O-N 3.09Å; S530-D532 WeakPolarHBondContact OG-CB 3.38Å; D532-D534 VanDerWaalsContact C-N 3.33Å; D532-D534 PolarHBondContact OD1-N 2.97Å; D532-S535 WeakPolarHBondContact OD1-CB 3.43Å; D532-S535 PolarHBondContact OD1-N 2.89Å; D532-S535 WeakPolarHBondContact OD2-CB 3.38Å; D532-M536 PolarHBondContact O-N 3.48Å; D532-M536 VanDerWaalsContact O-N 3.11Å
533L95.8Very high96Very high17 Ų1741.2 Ų41.29%0.08923%0.227CC..Hα-helixtrans-68.4-30-179.1-75.6164000113.3N531 M536 K537 E567 M568 Y571N531-L533 PolarHBondContact O-N 2.8Å; N531-L533 VanDerWaalsContact O-N 3.08Å; L533-M536 PolarHBondContact O-N 3.49Å; L533-K537 WeakPolarHBondContact O-CB 3.28Å; L533-K537 WeakPolarHBondContact O-CD 3.45Å; L533-K537 WeakPolarHBondContact O-CG 3.48Å; L533-K537 PolarHBondContact O-N 2.99Å; L533-E567 HydrophobicContact CD1-CB 4.09Å; L533-E567 HydrophobicContact CD1-CG 3.45Å; L533-E567 VanDerWaalsContact CD1-CG 3.45Å; L533-E567 WeakPolarHBondContact CD1-OE1 3.38Å; L533-E567 VanDerWaalsContact CD1-OE2 3.31Å; L533-E567 WeakPolarHBondContact CD1-OE2 3.38Å; L533-M568 HydrophobicContact CD2-CE 3.78Å; L533-M568 HydrophobicContact CD2-SD 4.06Å; L533-M568 HydrophobicContact CG-CE 4.02Å; L533-Y571 HydrophobicContact CD2-CD1 4.46Å; L533-Y571 HydrophobicContact CD2-CD2 4.42Å; L533-Y571 HydrophobicContact CD2-CG 3.97Å
534D95.4Very high96Very high90 Ų9038.8 Ų38.848%0.48121%0.214SC..Hα-helixtrans-72.2-38.5-179.5-67.1-31.3000111H498 D532 K537 S538H498-D534 HydrophobicContact CB-CB 4.45Å; D532-D534 VanDerWaalsContact C-N 3.33Å; D532-D534 PolarHBondContact OD1-N 2.97Å; D534-K537 IonicContact OD1-NZ 2.72Å; D534-S538 WeakPolarHBondContact O-CB 3.47Å; D534-S538 PolarHBondContact O-N 3.21Å; D534-S538 PolarHBondContact O-OG 3.41Å
535S95.6Very high95.9Very high15 Ų1543.1 Ų43.111%0.10524%0.238CC..Hα-helixtrans-58.7-51.4165.4-170.30000111.9H498 D532 K537 S538 W539H498-S535 WeakPolarHBondContact ND1-CA 3.47Å; H498-S535 PolarHBondContact ND1-N 3.44Å; D532-S535 WeakPolarHBondContact OD1-CB 3.43Å; D532-S535 PolarHBondContact OD1-N 2.89Å; D532-S535 WeakPolarHBondContact OD2-CB 3.38Å; S535-K537 VanDerWaalsContact C-N 3.33Å; S535-K537 PolarHBondContact O-N 3.05Å; S535-S538 WeakPolarHBondContact O-CB 3.15Å; S535-S538 PolarHBondContact O-N 3.3Å; S535-S538 VanDerWaalsContact O-N 3.08Å; S535-W539 PolarHBondContact O-N 3.17Å; S535-W539 PolarHBondContact OG-NE1 2.67Å
536M96.8Very high95.9Very high0 Ų042 Ų420%023%0.228CC..Hα-helixtrans-59.1-43.3-179.2-169.762.871.400112.1L524 A527 A528 D532 L533 W539 K540 L546 A556 M568 Y571 L572L524-M536 HydrophobicContact CB-CE 4.5Å; L524-M536 HydrophobicContact CD2-CE 4.33Å; L524-M536 HydrophobicContact CD2-SD 3.76Å; A527-M536 HydrophobicContact CB-CE 4.11Å; A528-M536 HydrophobicContact CB-CE 4.27Å; D532-M536 PolarHBondContact O-N 3.48Å; D532-M536 VanDerWaalsContact O-N 3.11Å; L533-M536 PolarHBondContact O-N 3.49Å; M536-W539 PolarHBondContact O-N 2.83Å; M536-K540 PolarHBondContact O-N 2.78Å; M536-L546 HydrophobicContact SD-CD1 4.31Å; M536-L546 HydrophobicContact SD-CD2 3.87Å; M536-A556 HydrophobicContact CE-CB 4.27Å; M536-M568 HydrophobicContact CB-CE 3.95Å; M536-M568 HydrophobicContact CB-SD 3.99Å; M536-M568 HydrophobicContact CE-CE 4.27Å; M536-M568 HydrophobicContact CE-SD 3.59Å; M536-M568 VanDerWaalsContact CE-SD 3.59Å; M536-M568 HydrophobicContact CG-CE 4.39Å; M536-M568 HydrophobicContact CG-SD 3.75Å; M536-M568 HydrophobicContact SD-SD 4.48Å; M536-Y571 HydrophobicContact CB-CE1 4.35Å; M536-Y571 HydrophobicContact CG-CD1 3.71Å; M536-Y571 HydrophobicContact CG-CE1 3.6Å; M536-L572 HydrophobicContact CE-CD2 3.95Å; M536-L572 HydrophobicContact CG-CD2 4.37Å; M536-L572 HydrophobicContact SD-CD2 3.85Å
537K97.1Very high95.9Very high70 Ų7038 Ų3830%0.30421%0.213SC..Hα-helixtrans-61.6-42.2174.3-73.7166.4-171166.80111.7I500 L533 D534 S535 K540 S541 Y571I500-K537 HydrophobicContact CD1-CB 3.89Å; L533-K537 WeakPolarHBondContact O-CB 3.28Å; L533-K537 WeakPolarHBondContact O-CD 3.45Å; L533-K537 WeakPolarHBondContact O-CG 3.48Å; L533-K537 PolarHBondContact O-N 2.99Å; D534-K537 IonicContact OD1-NZ 2.72Å; S535-K537 VanDerWaalsContact C-N 3.33Å; S535-K537 PolarHBondContact O-N 3.05Å; K537-K540 PolarHBondContact O-N 3.32Å; K537-S541 WeakPolarHBondContact O-CB 3.43Å; K537-S541 PolarHBondContact O-N 2.85Å; K537-S541 PolarHBondContact O-OG 3.12Å; K537-Y571 WeakPolarHBondContact CA-OH 3.28Å; K537-Y571 HydrophobicContact CG-CE2 3.76Å; K537-Y571 WeakPolarHBondContact CG-OH 3.4Å
538S96.4Very high95.8Very high0 Ų039 Ų390%022%0.218CC..Hα-helixtrans-63-42.7178.6-61.70000112.3H498 D534 S535 A542H498-S538 WeakPolarHBondContact CA-OG 3.45Å; D534-S538 WeakPolarHBondContact O-CB 3.47Å; D534-S538 PolarHBondContact O-N 3.21Å; D534-S538 PolarHBondContact O-OG 3.41Å; S535-S538 WeakPolarHBondContact O-CB 3.15Å; S535-S538 PolarHBondContact O-N 3.3Å; S535-S538 VanDerWaalsContact O-N 3.08Å; S538-A542 PolarHBondContact O-N 2.85Å; S538-A542 VanDerWaalsContact O-N 3.15Å
539W96.4Very high95.6Very high6 Ų640.9 Ų40.92%0.02324%0.235CC..Hα-helixtrans-62.2-44.3172.2-70.6110.2000111.8L492 I495 L513 I515 L520 N523 L524 S535 M536 A542 A544L492-W539 HydrophobicContact CD2-CH2 4.09Å; L492-W539 HydrophobicContact CD2-CZ3 4.13Å; I495-W539 HydrophobicContact CD1-CE3 4.15Å; I495-W539 HydrophobicContact CD1-CZ3 4.15Å; I495-W539 HydrophobicContact CG2-CD2 3.58Å; I495-W539 HydrophobicContact CG2-CE3 3.85Å; I495-W539 HydrophobicContact CG2-CG 4.11Å; I495-W539 HydrophobicContact CG2-CH2 4.01Å; I495-W539 HydrophobicContact CG2-CZ2 3.73Å; I495-W539 HydrophobicContact CG2-CZ3 4.08Å; L513-W539 HydrophobicContact CD1-CE3 4.41Å; L513-W539 HydrophobicContact CD1-CZ3 3.98Å; L513-W539 HydrophobicContact CD2-CE3 4.16Å; L513-W539 HydrophobicContact CD2-CZ3 4.29Å; I515-W539 HydrophobicContact CD1-CH2 3.71Å; I515-W539 HydrophobicContact CD1-CZ3 3.87Å; L520-W539 HydrophobicContact CD1-CD2 4.21Å; L520-W539 HydrophobicContact CD1-CE3 3.69Å; L520-W539 HydrophobicContact CD1-CZ3 3.95Å; N523-W539 HydrophobicContact CB-CH2 4.38Å; N523-W539 HydrophobicContact CB-CZ2 3.68Å; L524-W539 HydrophobicContact CD2-CB 3.92Å; L524-W539 HydrophobicContact CD2-CG 3.93Å; S535-W539 PolarHBondContact O-N 3.17Å; S535-W539 PolarHBondContact OG-NE1 2.67Å; M536-W539 PolarHBondContact O-N 2.83Å; W539-A542 WeakPolarHBondContact O-CB 3.2Å; W539-A542 PolarHBondContact O-N 2.81Å; W539-A544 HydrophobicContact CB-CB 4.05Å; W539-A544 HydrophobicContact CE3-CB 4.44Å; W539-A544 WeakPolarHBondContact O-CB 3.37Å; W539-A544 PolarHBondContact O-N 3.19Å
540K96.2Very high95.5Very high75 Ų7540.3 Ų40.333%0.32623%0.225SC..Hα-helixtrans-63.2-44.4177.9-17863.3-176.8-166.50112.3M536 K537 A542 E543 L546 N575M536-K540 PolarHBondContact O-N 2.78Å; K537-K540 PolarHBondContact O-N 3.32Å; K540-A542 PolarHBondContact O-N 3.43Å; K540-E543 WeakPolarHBondContact O-CA 3.39Å; K540-E543 PolarHBondContact O-N 2.99Å; K540-L546 HydrophobicContact CB-CD1 4.3Å; K540-L546 HydrophobicContact CD-CD1 3.89Å; K540-L546 HydrophobicContact CD-CG 4.22Å; K540-L546 HydrophobicContact CG-CD1 4.46Å; K540-N575 HydrophobicContact CD-CB 4.46Å; K540-N575 WeakPolarHBondContact CE-OD1 3.21Å; K540-N575 PolarHBondContact NZ-O 2.82Å
541S95.7Very high95.2Very high35 Ų3545.4 Ų45.425%0.24523%0.233CC..Hα-helixtrans-63.2-23.4176.3-670000112.8K537 E543K537-S541 WeakPolarHBondContact O-CB 3.43Å; K537-S541 PolarHBondContact O-N 2.85Å; K537-S541 PolarHBondContact O-OG 3.12Å; S541-E543 PolarHBondContact O-N 3.36Å
542A95.6Very high95Very high0 Ų045.9 Ų45.90%023%0.234CC..THydrogen-bonded Turntrans-82.75.717200000114L491 I495 V503 R507 L513 S538 W539 K540 A544L491-A542 HydrophobicContact CD1-CB 4.38Å; I495-A542 HydrophobicContact CD1-CB 3.45Å; I495-A542 VanDerWaalsContact CD1-CB 3.45Å; I495-A542 HydrophobicContact CG1-CB 4Å; V503-A542 HydrophobicContact CG1-CB 3.75Å; R507-A542 PolarHBondContact NH1-O 3.46Å; L513-A542 HydrophobicContact CD1-CB 4.48Å; S538-A542 PolarHBondContact O-N 2.85Å; S538-A542 VanDerWaalsContact O-N 3.15Å; W539-A542 WeakPolarHBondContact O-CB 3.2Å; W539-A542 PolarHBondContact O-N 2.81Å; K540-A542 PolarHBondContact O-N 3.43Å; A542-A544 VanDerWaalsContact C-N 3.33Å
543E94.4Very high94.9Very high113 Ų11344 Ų4453%0.52823%0.226SC..THydrogen-bonded Turntrans64.830.6-175-56.4169.8-141.500113.3K231 R507 K540 S541K231-E543 IonicContact NZ-OE1 2.88Å; R507-E543 IonicContact CZ-OE1 2.92Å; R507-E543 IonicContact CZ-OE2 2.97Å; R507-E543 VanDerWaalsContact NE-CD 3.34Å; R507-E543 IonicContact NE-OE1 3.09Å; R507-E543 PolarHBondContact NE-OE1 3.08Å; R507-E543 IonicContact NE-OE2 2.9Å; R507-E543 IonicContact NH2-OE1 3.37Å; R507-E543 PolarHBondContact NH2-OE1 2.77Å; R507-E543 VanDerWaalsContact NH2-OE1 3.09Å; R507-E543 IonicContact NH2-OE2 3.34Å; R507-E543 PolarHBondContact NH2-OE2 2.97Å; K540-E543 WeakPolarHBondContact O-CA 3.39Å; K540-E543 PolarHBondContact O-N 2.99Å; S541-E543 PolarHBondContact O-N 3.36Å
544A95Very high94.8Very high6 Ų647.4 Ų47.45%0.0524%0.238CC..  trans-64.9140.5174.500000111.9L513 L520 W539 A542 L546L513-A544 HydrophobicContact CD2-CB 3.56Å; L520-A544 HydrophobicContact CD1-CB 4.08Å; L520-A544 HydrophobicContact CD2-CB 4.27Å; W539-A544 HydrophobicContact CB-CB 4.05Å; W539-A544 HydrophobicContact CE3-CB 4.44Å; W539-A544 WeakPolarHBondContact O-CB 3.37Å; W539-A544 PolarHBondContact O-N 3.19Å; A542-A544 VanDerWaalsContact C-N 3.33Å; A544-L546 HydrophobicContact CB-CD2 4.49Å; A544-L546 PolarHBondContact O-N 3.01Å
545N94.5Very high94.9Very high93 Ų9343.3 Ų43.350%0.49722%0.217SC..  trans-74.3104.2169.8-179.55000109.8S547 V548N545-S547 PolarHBondContact O-N 3.36Å; N545-S547 WeakPolarHBondContact OD1-CB 3.42Å; N545-S547 PolarHBondContact OD1-N 3.02Å; N545-V548 HydrophobicContact CB-CG2 3.89Å; N545-V548 WeakPolarHBondContact O-CG2 3.33Å; N545-V548 PolarHBondContact O-N 3.08Å
546L96.4Very high95Very high5 Ų542.8 Ų42.83%0.02621%0.213CC..THydrogen-bonded Turntrans-72.5-11.2179.9-57.6-171.1000113.7L524 M536 K540 A544 V548 L572 N575 V577L524-L546 HydrophobicContact CD1-CD2 4.18Å; L524-L546 HydrophobicContact CD2-CD2 3.71Å; M536-L546 HydrophobicContact SD-CD1 4.31Å; M536-L546 HydrophobicContact SD-CD2 3.87Å; K540-L546 HydrophobicContact CB-CD1 4.3Å; K540-L546 HydrophobicContact CD-CD1 3.89Å; K540-L546 HydrophobicContact CD-CG 4.22Å; K540-L546 HydrophobicContact CG-CD1 4.46Å; A544-L546 HydrophobicContact CB-CD2 4.49Å; A544-L546 PolarHBondContact O-N 3.01Å; L546-V548 VanDerWaalsContact C-N 3.35Å; L546-L572 HydrophobicContact CB-CD2 4.46Å; L546-L572 HydrophobicContact CD1-CD2 4.17Å; L546-N575 HydrophobicContact CD1-CB 3.94Å; L546-V577 HydrophobicContact CB-CG2 3.59Å
547S95.6Very high95Very high49 Ų4942.8 Ų42.834%0.34321%0.213SC..THydrogen-bonded Turntrans-90.84.9-179.4-55.20000113.3N545 A549N545-S547 PolarHBondContact O-N 3.36Å; N545-S547 WeakPolarHBondContact OD1-CB 3.42Å; N545-S547 PolarHBondContact OD1-N 3.02Å; S547-A549 PolarHBondContact O-N 3.02Å
548V94.4Very high95Very high24 Ų2439.6 Ų39.615%0.14520%0.199CC..  trans-62.8129.2177177.80000109.7P517 L520 C521 N545 L546P517-V548 HydrophobicContact CB-CG1 4.07Å; P517-V548 WeakPolarHBondContact O-CG1 3.34Å; L520-V548 HydrophobicContact CD2-CG2 4.11Å; C521-V548 HydrophobicContact CB-CG1 3.85Å; N545-V548 HydrophobicContact CB-CG2 3.89Å; N545-V548 WeakPolarHBondContact O-CG2 3.33Å; N545-V548 PolarHBondContact O-N 3.08Å; L546-V548 VanDerWaalsContact C-N 3.35Å
549A93.5Very high95.1Very high41 Ų4141 Ų4134%0.33921%0.207SC..  trans-97.1152.5177.700000111.8S547 R554 T555S547-A549 PolarHBondContact O-N 3.02Å; A549-R554 CarbonylContact C-O 3.55Å; A549-R554 VanDerWaalsContact CA-O 3.27Å; A549-R554 WeakPolarHBondContact CA-O 3.44Å; A549-T555 HydrophobicContact CB-CG2 4.23Å
550D93Very high95.1Very high30 Ų3040.7 Ų40.716%0.1621%0.206CC..  trans-75.3-176.3167.872.26.5000112E552 G553 R554D550-E552 PolarHBondContact O-N 3.37Å; D550-E552 WeakPolarHBondContact OD1-CA 3.5Å; D550-E552 WeakPolarHBondContact OD1-CB 3.36Å; D550-E552 PolarHBondContact OD1-N 3.39Å; D550-G553 PolarHBondContact O-N 3.37Å; D550-G553 PolarHBondContact OD1-N 3.37Å; D550-G553 VanDerWaalsContact OD1-N 3.12Å; D550-R554 PolarHBondContact N-O 3.19Å; D550-R554 WeakPolarHBondContact OD1-CB 3.32Å; D550-R554 PolarHBondContact OD1-N 3.29Å; D550-R554 IonicContact OD1-NE 2.7Å; D550-R554 IonicContact OD2-CZ 3.43Å; D550-R554 VanDerWaalsContact OD2-CZ 3.23Å; D550-R554 IonicContact OD2-NE 2.71Å; D550-R554 PolarHBondContact OD2-NE 3.17Å; D550-R554 IonicContact OD2-NH2 2.77Å; D550-R554 PolarHBondContact OD2-NH2 2.96Å
551W89.7Confident95.2Very high182 Ų18237.1 Ų37.169%0.68919%0.191SC*.THydrogen-bonded Turntrans-67.7-10.617960.8-88.9000114H584W551-H584 PolarHBondContact O-CE1 3.22Å; W551-H584 PolarHBondContact O-ND1 3.02Å; W551-H584 VanDerWaalsContact O-ND1 3.14Å
552E92.1Very high95.2Very high62 Ų6237.7 Ų37.729%0.2920%0.195SC..THydrogen-bonded Turntrans-98.43.8172.2-63.7-176.5132.900111.8D550 R554 D583 H584D550-E552 PolarHBondContact O-N 3.37Å; D550-E552 WeakPolarHBondContact OD1-CA 3.5Å; D550-E552 WeakPolarHBondContact OD1-CB 3.36Å; D550-E552 PolarHBondContact OD1-N 3.39Å; E552-R554 VanDerWaalsContact C-N 3.29Å; E552-R554 HydrophobicContact CB-CG 4.24Å; E552-R554 PolarHBondContact O-N 2.98Å; E552-R554 IonicContact OE2-CZ 3.52Å; E552-R554 IonicContact OE2-NE 3.17Å; E552-R554 PolarHBondContact OE2-NE 3.39Å; E552-R554 IonicContact OE2-NH1 3.88Å; E552-R554 PolarHBondContact OE2-NH1 3.3Å; E552-R554 VanDerWaalsContact OE2-NH1 3.12Å; E552-R554 IonicContact OE2-NH2 3.18Å; E552-R554 PolarHBondContact OE2-NH2 3.39Å; E552-D583 WeakPolarHBondContact O-CB 3.36Å; E552-H584 WeakPolarHBondContact O-CB 3.34Å; E552-H584 PolarHBondContact O-N 3.43Å
553G93.1Very high95.2Very high11 Ų1140.9 Ų40.911%0.11321%0.214CC..SBendtrans78.58.1-176.700000114.1D550D550-G553 PolarHBondContact O-N 3.37Å; D550-G553 PolarHBondContact OD1-N 3.37Å; D550-G553 VanDerWaalsContact OD1-N 3.12Å
554R95Very high95.3Very high88 Ų8836.4 Ų36.433%0.33220%0.198SC..  trans-84.1133.9-179.5-57.5178.8-57.7-162.6-10111A549 D550 E552 H558 D583A549-R554 CarbonylContact C-O 3.55Å; A549-R554 VanDerWaalsContact CA-O 3.27Å; A549-R554 WeakPolarHBondContact CA-O 3.44Å; D550-R554 PolarHBondContact N-O 3.19Å; D550-R554 WeakPolarHBondContact OD1-CB 3.32Å; D550-R554 PolarHBondContact OD1-N 3.29Å; D550-R554 IonicContact OD1-NE 2.7Å; D550-R554 IonicContact OD2-CZ 3.43Å; D550-R554 VanDerWaalsContact OD2-CZ 3.23Å; D550-R554 IonicContact OD2-NE 2.71Å; D550-R554 PolarHBondContact OD2-NE 3.17Å; D550-R554 IonicContact OD2-NH2 2.77Å; D550-R554 PolarHBondContact OD2-NH2 2.96Å; E552-R554 VanDerWaalsContact C-N 3.29Å; E552-R554 HydrophobicContact CB-CG 4.24Å; E552-R554 PolarHBondContact O-N 2.98Å; E552-R554 IonicContact OE2-CZ 3.52Å; E552-R554 IonicContact OE2-NE 3.17Å; E552-R554 PolarHBondContact OE2-NE 3.39Å; E552-R554 IonicContact OE2-NH1 3.88Å; E552-R554 PolarHBondContact OE2-NH1 3.3Å; E552-R554 VanDerWaalsContact OE2-NH1 3.12Å; E552-R554 IonicContact OE2-NH2 3.18Å; E552-R554 PolarHBondContact OE2-NH2 3.39Å; R554-H558 HydrophobicContact CB-CB 4.14Å; R554-D583 HydrophobicContact CG-CB 3.75Å
555T96.5Very high95.4Very high5 Ų537.5 Ų37.53%0.03120%0.203CC..  trans-97.5170.9173.666.20000111.5A549 L557 H558 V559A549-T555 HydrophobicContact CB-CG2 4.23Å; T555-L557 PolarHBondContact O-N 3.16Å; T555-L557 VanDerWaalsContact O-N 3.13Å; T555-L557 PolarHBondContact OG1-N 3.15Å; T555-H558 PolarHBondContact N-ND1 2.98Å; T555-H558 VanDerWaalsContact N-ND1 3.15Å; T555-H558 WeakPolarHBondContact O-CB 3.43Å; T555-H558 PolarHBondContact O-N 2.81Å; T555-H558 PolarHBondContact OG1-ND1 2.77Å; T555-V559 PolarHBondContact O-N 2.57Å
556A97Very high95.5Very high3 Ų338 Ų383%0.02520%0.203CC..Hα-helixtrans-53.4-32.8172.200000112.9L524 A528 M536 V559 A560 L572L524-A556 HydrophobicContact CB-CB 4.02Å; A528-A556 HydrophobicContact CB-CB 4.15Å; A528-A556 WeakPolarHBondContact CB-O 3.44Å; M536-A556 HydrophobicContact CE-CB 4.27Å; A556-V559 PolarHBondContact O-N 3.12Å; A556-A560 PolarHBondContact O-N 3.46Å; A556-L572 HydrophobicContact CB-CD1 4.01Å; A556-L572 HydrophobicContact CB-CD2 4.16Å
557L97.8Very high95.6Very high0 Ų043.7 Ų43.70%023%0.229CC..Hα-helixtrans-68-37.6178-17664.5000112.3T555 V559 A561 V569 L572 L573 V577 P579 A589T555-L557 PolarHBondContact O-N 3.16Å; T555-L557 VanDerWaalsContact O-N 3.13Å; T555-L557 PolarHBondContact OG1-N 3.15Å; L557-V559 VanDerWaalsContact C-N 3.28Å; L557-V559 PolarHBondContact O-N 3.32Å; L557-A561 WeakPolarHBondContact O-CB 3.4Å; L557-A561 PolarHBondContact O-N 2.94Å; L557-V569 HydrophobicContact CD1-CB 4.42Å; L557-V569 HydrophobicContact CD1-CG1 4.13Å; L557-V569 HydrophobicContact CD1-CG2 4.3Å; L557-L572 HydrophobicContact CB-CD1 4.2Å; L557-L572 HydrophobicContact CD1-CB 4.05Å; L557-L572 HydrophobicContact CD1-CD1 4.31Å; L557-L573 HydrophobicContact CD1-CD2 4.27Å; L557-L573 HydrophobicContact CD1-CG 4.18Å; L557-L573 HydrophobicContact CD2-CD2 3.75Å; L557-V577 HydrophobicContact CB-CG1 3.75Å; L557-V577 HydrophobicContact CD2-CG1 4.14Å; L557-P579 HydrophobicContact CD2-CB 4.28Å; L557-A589 HydrophobicContact CB-CB 4.39Å; L557-A589 HydrophobicContact CD2-CB 3.93Å; L557-A589 HydrophobicContact CG-CB 3.64Å
558H97.7Very high95.7Very high3 Ų341.3 Ų41.31%0.01421%0.213CC..Hα-helixtrans-60.7-41.7173.4-68.980.7000111.1R554 T555 S562 S581 H587R554-H558 HydrophobicContact CB-CB 4.14Å; T555-H558 PolarHBondContact N-ND1 2.98Å; T555-H558 VanDerWaalsContact N-ND1 3.15Å; T555-H558 WeakPolarHBondContact O-CB 3.43Å; T555-H558 PolarHBondContact O-N 2.81Å; T555-H558 PolarHBondContact OG1-ND1 2.77Å; H558-S562 VanDerWaalsContact O-CB 3.28Å; H558-S562 WeakPolarHBondContact O-CB 3.4Å; H558-S562 PolarHBondContact O-N 3.15Å; H558-S581 PolarHBondContact CE1-O 3.17Å; H558-S581 PolarHBondContact NE2-O 3.48Å; H558-S581 VanDerWaalsContact NE2-O 3.12Å; H558-H587 PolarHBondContact NE2-O 2.98Å; H558-H587 VanDerWaalsContact NE2-O 3.15Å
559V96.8Very high95.8Very high29 Ų2940.2 Ų40.218%0.17621%0.206CC..Hα-helixtrans-68.4-49.6-180-178.70000110.9A525 A528 A529 T555 A556 L557 A561 S562 V563A525-V559 HydrophobicContact CB-CG2 4.05Å; A528-V559 HydrophobicContact CB-CB 4.27Å; A528-V559 HydrophobicContact CB-CG1 4.34Å; A529-V559 HydrophobicContact CB-CG1 3.84Å; T555-V559 PolarHBondContact O-N 2.57Å; A556-V559 PolarHBondContact O-N 3.12Å; L557-V559 VanDerWaalsContact C-N 3.28Å; L557-V559 PolarHBondContact O-N 3.32Å; V559-A561 VanDerWaalsContact C-N 3.3Å; V559-A561 PolarHBondContact O-N 3.15Å; V559-S562 PolarHBondContact O-N 3.28Å; V559-V563 HydrophobicContact CG1-CG2 4.49Å; V559-V563 WeakPolarHBondContact O-CG2 3.47Å; V559-V563 PolarHBondContact O-N 3.4Å
560A97.8Very high96Very high0 Ų040.3 Ų40.30%020%0.204CC..Hα-helixtrans-58.1-42.7177.800000112A528 A556 V563 G564 N565 M568 V569 L572A528-A560 HydrophobicContact CB-CB 4.18Å; A556-A560 PolarHBondContact O-N 3.46Å; A560-V563 PolarHBondContact O-N 3.05Å; A560-G564 PolarHBondContact O-N 3.12Å; A560-N565 PolarHBondContact O-N 3.14Å; A560-M568 HydrophobicContact CB-CB 4.13Å; A560-M568 HydrophobicContact CB-CG 3.73Å; A560-V569 HydrophobicContact CB-CG2 3.77Å; A560-L572 HydrophobicContact CB-CD1 4.11Å
561A97.6Very high96.2Very high0 Ų041 Ų410%021%0.205CC..Hα-helixtrans-66-39.8177.200000112.8L557 V559 V563 V569 A589 A593 H598 I605L557-A561 WeakPolarHBondContact O-CB 3.4Å; L557-A561 PolarHBondContact O-N 2.94Å; V559-A561 VanDerWaalsContact C-N 3.3Å; V559-A561 PolarHBondContact O-N 3.15Å; A561-V563 VanDerWaalsContact C-N 3.35Å; A561-V569 HydrophobicContact CB-CG2 4.44Å; A561-A589 HydrophobicContact CB-CB 4.16Å; A561-A589 WeakPolarHBondContact CB-O 3.34Å; A561-A593 HydrophobicContact CB-CB 4.1Å; A561-A593 WeakPolarHBondContact O-CA 3.46Å; A561-H598 PolarHBondContact O-CD2 3.1Å; A561-I605 HydrophobicContact CB-CD1 4.01Å
562S95.9Very high96.6Very high47 Ų4732.4 Ų32.433%0.32917%0.172SC..Hα-helixtrans-69.8-28.6179.1-175.60000113.7H558 V559 S596 H598H558-S562 VanDerWaalsContact O-CB 3.28Å; H558-S562 WeakPolarHBondContact O-CB 3.4Å; H558-S562 PolarHBondContact O-N 3.15Å; V559-S562 PolarHBondContact O-N 3.28Å; S562-S596 WeakPolarHBondContact O-CB 3.36Å; S562-S596 PolarHBondContact O-OG 3.36Å; S562-S596 VanDerWaalsContact O-OG 3.12Å; S562-H598 PolarHBondContact O-CD2 3.36Å; S562-H598 PolarHBondContact O-NE2 3.31Å
563V96.2Very high96.8Very high67 Ų6729.7 Ų29.741%0.40616%0.16SC..Hα-helixtrans-91.6-23.5-179.8177.80000112.1A529 V559 A560 A561 H598A529-V563 HydrophobicContact CB-CG2 4.4Å; V559-V563 HydrophobicContact CG1-CG2 4.49Å; V559-V563 WeakPolarHBondContact O-CG2 3.47Å; V559-V563 PolarHBondContact O-N 3.4Å; A560-V563 PolarHBondContact O-N 3.05Å; A561-V563 VanDerWaalsContact C-N 3.35Å; V563-H598 VanDerWaalsContact C-NE2 3.28Å; V563-H598 PolarHBondContact O-CE1 3.23Å; V563-H598 VanDerWaalsContact O-CE1 3.28Å; V563-H598 PolarHBondContact O-NE2 2.75Å
564G96.5Very high97Very high19 Ų1934.6 Ų34.620%0.19618%0.183CC..THydrogen-bonded Turntrans94.823.9178.600000114.8A560 E566 H598A560-G564 PolarHBondContact O-N 3.12Å; G564-E566 PolarHBondContact O-N 2.91Å; G564-E566 VanDerWaalsContact O-N 3.13Å; G564-H598 WeakPolarHBondContact CA-ND1 3.31Å; G564-H598 PolarHBondContact N-CD2 3.07Å
565N96.8Very high97Very high29 Ų2932.4 Ų32.416%0.15518%0.178CC..  trans-84.784.5-177.9-68.6-23.3000111A528 A529 N531 A560 E567 M568 V569A528-N565 PolarHBondContact O-ND2 2.81Å; A529-N565 PolarHBondContact O-ND2 3.08Å; N531-N565 HydrophobicContact CB-CB 4.17Å; N531-N565 PolarHBondContact N-ND2 3.15Å; A560-N565 PolarHBondContact O-N 3.14Å; N565-E567 VanDerWaalsContact C-N 3.35Å; N565-E567 PolarHBondContact O-N 3.37Å; N565-M568 HydrophobicContact CB-CB 3.99Å; N565-M568 PolarHBondContact O-N 3.43Å; N565-V569 WeakPolarHBondContact O-CG2 2.94Å; N565-V569 PolarHBondContact O-N 3.28Å
566E96.9Very high96.9Very high105 Ų10534.9 Ų34.949%0.49120%0.204SC..Hα-helixtrans-57.5-42.1-174.2-66.5-176.7-156.600113.4G564 V569 S570 G600 L604G564-E566 PolarHBondContact O-N 2.91Å; G564-E566 VanDerWaalsContact O-N 3.13Å; E566-V569 PolarHBondContact O-N 3.34Å; E566-S570 PolarHBondContact O-N 3.03Å; E566-G600 WeakPolarHBondContact OE1-CA 3.35Å; E566-L604 HydrophobicContact CB-CD1 3.9Å; E566-L604 HydrophobicContact CG-CD1 4.44Å; E566-L604 WeakPolarHBondContact O-CD1 3.39Å
567E96.8Very high96.8Very high123 Ų12334.8 Ų34.858%0.57520%0.204SC*.Hα-helixtrans-66.1-44.4-179.3-161-176.8177.400111.7L533 N565 S570 Y571L533-E567 HydrophobicContact CD1-CB 4.09Å; L533-E567 HydrophobicContact CD1-CG 3.45Å; L533-E567 VanDerWaalsContact CD1-CG 3.45Å; L533-E567 WeakPolarHBondContact CD1-OE1 3.38Å; L533-E567 VanDerWaalsContact CD1-OE2 3.31Å; L533-E567 WeakPolarHBondContact CD1-OE2 3.38Å; N565-E567 VanDerWaalsContact C-N 3.35Å; N565-E567 PolarHBondContact O-N 3.37Å; E567-S570 PolarHBondContact O-N 2.98Å; E567-Y571 PolarHBondContact O-N 3.13Å
568M97.9Very high96.7Very high0 Ų036.8 Ų36.80%022%0.218CC..Hα-helixtrans-62.6-40.6173.3-176.164.664.400112.5A528 N531 L533 M536 A560 N565 Y571 L572A528-M568 HydrophobicContact CB-CG 4.23Å; N531-M568 WeakPolarHBondContact OD1-CB 3.45Å; N531-M568 PolarHBondContact OD1-N 2.7Å; L533-M568 HydrophobicContact CD2-CE 3.78Å; L533-M568 HydrophobicContact CD2-SD 4.06Å; L533-M568 HydrophobicContact CG-CE 4.02Å; M536-M568 HydrophobicContact CB-CE 3.95Å; M536-M568 HydrophobicContact CB-SD 3.99Å; M536-M568 HydrophobicContact CE-CE 4.27Å; M536-M568 HydrophobicContact CE-SD 3.59Å; M536-M568 VanDerWaalsContact CE-SD 3.59Å; M536-M568 HydrophobicContact CG-CE 4.39Å; M536-M568 HydrophobicContact CG-SD 3.75Å; M536-M568 HydrophobicContact SD-SD 4.48Å; A560-M568 HydrophobicContact CB-CB 4.13Å; A560-M568 HydrophobicContact CB-CG 3.73Å; N565-M568 HydrophobicContact CB-CB 3.99Å; N565-M568 PolarHBondContact O-N 3.43Å; M568-Y571 PolarHBondContact O-N 2.94Å; M568-L572 HydrophobicContact CG-CD1 3.84Å; M568-L572 HydrophobicContact CG-CG 4.28Å; M568-L572 WeakPolarHBondContact O-CB 3.18Å; M568-L572 VanDerWaalsContact O-CG 3.29Å; M568-L572 WeakPolarHBondContact O-CG 3.37Å; M568-L572 PolarHBondContact O-N 2.89Å; M568-L572 HydrophobicContact SD-CD1 4.22Å; M568-L572 HydrophobicContact SD-CG 4.15Å
569V97.8Very high96.6Very high0 Ų036.7 Ų36.70%022%0.217CC..Hα-helixtrans-59.4-48.7175.5166.40000110.4L557 A560 A561 N565 E566 Y571 L572 L573 C601 L604 I605L557-V569 HydrophobicContact CD1-CB 4.42Å; L557-V569 HydrophobicContact CD1-CG1 4.13Å; L557-V569 HydrophobicContact CD1-CG2 4.3Å; A560-V569 HydrophobicContact CB-CG2 3.77Å; A561-V569 HydrophobicContact CB-CG2 4.44Å; N565-V569 WeakPolarHBondContact O-CG2 2.94Å; N565-V569 PolarHBondContact O-N 3.28Å; E566-V569 PolarHBondContact O-N 3.34Å; V569-Y571 PolarHBondContact O-N 2.98Å; V569-L572 PolarHBondContact O-N 3.21Å; V569-L573 HydrophobicContact CG1-CD1 3.82Å; V569-L573 HydrophobicContact CG1-CG 4.49Å; V569-L573 VanDerWaalsContact O-CG 3.23Å; V569-L573 WeakPolarHBondContact O-CG 3.29Å; V569-L573 PolarHBondContact O-N 3.39Å; V569-L573 VanDerWaalsContact O-N 3.1Å; V569-C601 HydrophobicContact CG2-CB 4.23Å; V569-L604 HydrophobicContact CG1-CB 4.25Å; V569-I605 HydrophobicContact CG1-CD1 4.12Å; V569-I605 HydrophobicContact CG1-CG1 3.67Å
570S97.4Very high96.5Very high44 Ų4440.3 Ų40.331%0.30823%0.231SC..Hα-helixtrans-57.1-50175.6-164.70000110.9E566 E567 L572 L573 D574E566-S570 PolarHBondContact O-N 3.03Å; E567-S570 PolarHBondContact O-N 2.98Å; S570-L572 PolarHBondContact O-N 3.38Å; S570-L573 PolarHBondContact O-N 2.93Å; S570-D574 WeakPolarHBondContact O-CB 3.46Å; S570-D574 PolarHBondContact O-N 3.48Å; S570-D574 PolarHBondContact OG-OD2 3.4Å
571Y97.6Very high96.3Very high45 Ų4542.7 Ų42.718%0.17625%0.247CC..Hα-helixtrans-59.3-44.1-178.4-175.2-91.1000112.9L533 M536 K537 E567 M568 V569 N575L533-Y571 HydrophobicContact CD2-CD1 4.46Å; L533-Y571 HydrophobicContact CD2-CD2 4.42Å; L533-Y571 HydrophobicContact CD2-CG 3.97Å; M536-Y571 HydrophobicContact CB-CE1 4.35Å; M536-Y571 HydrophobicContact CG-CD1 3.71Å; M536-Y571 HydrophobicContact CG-CE1 3.6Å; K537-Y571 WeakPolarHBondContact CA-OH 3.28Å; K537-Y571 HydrophobicContact CG-CE2 3.76Å; K537-Y571 WeakPolarHBondContact CG-OH 3.4Å; E567-Y571 PolarHBondContact O-N 3.13Å; M568-Y571 PolarHBondContact O-N 2.94Å; V569-Y571 PolarHBondContact O-N 2.98Å; Y571-N575 WeakPolarHBondContact CE1-ND2 3.49Å; Y571-N575 WeakPolarHBondContact CE2-ND2 3.17Å; Y571-N575 VanDerWaalsContact CZ-ND2 3.29Å; Y571-N575 WeakPolarHBondContact O-CB 3.49Å; Y571-N575 PolarHBondContact O-N 3.46Å; Y571-N575 VanDerWaalsContact O-N 3.08Å; Y571-N575 PolarHBondContact O-ND2 3.34Å
572L97.5Very high96.2Very high0 Ų046.5 Ų46.50%027%0.271CS..Hα-helixtrans-66.4-40.6-180-73.1170.1000112.2M536 L546 A556 L557 A560 M568 V569 S570 N575 G576 V577M536-L572 HydrophobicContact CE-CD2 3.95Å; M536-L572 HydrophobicContact CG-CD2 4.37Å; M536-L572 HydrophobicContact SD-CD2 3.85Å; L546-L572 HydrophobicContact CB-CD2 4.46Å; L546-L572 HydrophobicContact CD1-CD2 4.17Å; A556-L572 HydrophobicContact CB-CD1 4.01Å; A556-L572 HydrophobicContact CB-CD2 4.16Å; L557-L572 HydrophobicContact CB-CD1 4.2Å; L557-L572 HydrophobicContact CD1-CB 4.05Å; L557-L572 HydrophobicContact CD1-CD1 4.31Å; A560-L572 HydrophobicContact CB-CD1 4.11Å; M568-L572 HydrophobicContact CG-CD1 3.84Å; M568-L572 HydrophobicContact CG-CG 4.28Å; M568-L572 WeakPolarHBondContact O-CB 3.18Å; M568-L572 VanDerWaalsContact O-CG 3.29Å; M568-L572 WeakPolarHBondContact O-CG 3.37Å; M568-L572 PolarHBondContact O-N 2.89Å; M568-L572 HydrophobicContact SD-CD1 4.22Å; M568-L572 HydrophobicContact SD-CG 4.15Å; V569-L572 PolarHBondContact O-N 3.21Å; S570-L572 PolarHBondContact O-N 3.38Å; L572-N575 CarbonylContact O-C 3.57Å; L572-N575 PolarHBondContact O-N 2.87Å; L572-G576 PolarHBondContact O-N 3.11Å; L572-V577 HydrophobicContact CB-CB 4.32Å; L572-V577 HydrophobicContact CB-CG2 4.25Å; L572-V577 HydrophobicContact CD2-CG2 4.06Å; L572-V577 WeakPolarHBondContact O-CB 3.36Å; L572-V577 WeakPolarHBondContact O-CG2 3.36Å; L572-V577 PolarHBondContact O-N 3.38Å
573L97Very high96.2Very high5 Ų544.7 Ų44.73%0.02626%0.257CS..Hα-helixtrans-64.2-47.8176-68.5170.4000111L557 V569 S570 N575 G576 P579 I605 F608L557-L573 HydrophobicContact CD1-CD2 4.27Å; L557-L573 HydrophobicContact CD1-CG 4.18Å; L557-L573 HydrophobicContact CD2-CD2 3.75Å; V569-L573 HydrophobicContact CG1-CD1 3.82Å; V569-L573 HydrophobicContact CG1-CG 4.49Å; V569-L573 VanDerWaalsContact O-CG 3.23Å; V569-L573 WeakPolarHBondContact O-CG 3.29Å; V569-L573 PolarHBondContact O-N 3.39Å; V569-L573 VanDerWaalsContact O-N 3.1Å; S570-L573 PolarHBondContact O-N 2.93Å; L573-N575 PolarHBondContact O-N 3.12Å; L573-N575 VanDerWaalsContact O-N 3.16Å; L573-G576 PolarHBondContact O-N 2.92Å; L573-P579 HydrophobicContact CD2-CB 3.98Å; L573-P579 HydrophobicContact CD2-CG 4.21Å; L573-I605 HydrophobicContact CD1-CG1 4.12Å; L573-F608 HydrophobicContact CB-CD1 4.42Å; L573-F608 HydrophobicContact CB-CD2 3.72Å; L573-F608 HydrophobicContact CB-CE2 3.83Å; L573-F608 HydrophobicContact CB-CG 4.02Å; L573-F608 HydrophobicContact CB-CZ 4.22Å; L573-F608 HydrophobicContact CD1-CB 3.93Å; L573-F608 HydrophobicContact CD1-CD2 4.47Å; L573-F608 HydrophobicContact CD1-CG 4.15Å; L573-F608 HydrophobicContact CD2-CB 4.48Å; L573-F608 HydrophobicContact CD2-CD1 3.87Å; L573-F608 HydrophobicContact CD2-CE1 4.21Å; L573-F608 HydrophobicContact CD2-CG 4.08Å; L573-F608 HydrophobicContact CG-CD2 4.49Å; L573-F608 HydrophobicContact CG-CG 4.31Å; L573-F608 WeakPolarHBondContact O-CE2 3.41Å; L573-F608 WeakPolarHBondContact O-CZ 3.15Å
574D96Very high96.1Very high114 Ų11448.5 Ų48.561%0.6127%0.271SS*.Hα-helixtrans-61.4-24.7177.5-66.1-24.6000112.4S570S570-D574 WeakPolarHBondContact O-CB 3.46Å; S570-D574 PolarHBondContact O-N 3.48Å; S570-D574 PolarHBondContact OG-OD2 3.4Å
575N95.8Very high95.9Very high43 Ų4352.2 Ų52.223%0.2329%0.289CS..THydrogen-bonded Turntrans-95.413177.1-78.3-85000114.6K540 L546 Y571 L572 L573K540-N575 HydrophobicContact CD-CB 4.46Å; K540-N575 WeakPolarHBondContact CE-OD1 3.21Å; K540-N575 PolarHBondContact NZ-O 2.82Å; L546-N575 HydrophobicContact CD1-CB 3.94Å; Y571-N575 WeakPolarHBondContact CE1-ND2 3.49Å; Y571-N575 WeakPolarHBondContact CE2-ND2 3.17Å; Y571-N575 VanDerWaalsContact CZ-ND2 3.29Å; Y571-N575 WeakPolarHBondContact O-CB 3.49Å; Y571-N575 PolarHBondContact O-N 3.46Å; Y571-N575 VanDerWaalsContact O-N 3.08Å; Y571-N575 PolarHBondContact O-ND2 3.34Å; L572-N575 CarbonylContact O-C 3.57Å; L572-N575 PolarHBondContact O-N 2.87Å; L573-N575 PolarHBondContact O-N 3.12Å; L573-N575 VanDerWaalsContact O-N 3.16Å
576G94.2Very high95.8Very high56 Ų5653 Ų5358%0.57730%0.304SS*.THydrogen-bonded Turntrans87.415.5168.500000115.6L572 L573 S578L572-G576 PolarHBondContact O-N 3.11Å; L573-G576 PolarHBondContact O-N 2.92Å; G576-S578 PolarHBondContact O-N 3.36Å
577V95.9Very high95.8Very high1 Ų151 Ų511%0.00630%0.295CS..  trans-74.8117.5173.7-176.50000109.1L546 L557 L572L546-V577 HydrophobicContact CB-CG2 3.59Å; L557-V577 HydrophobicContact CB-CG1 3.75Å; L557-V577 HydrophobicContact CD2-CG1 4.14Å; L572-V577 HydrophobicContact CB-CB 4.32Å; L572-V577 HydrophobicContact CB-CG2 4.25Å; L572-V577 HydrophobicContact CD2-CG2 4.06Å; L572-V577 WeakPolarHBondContact O-CB 3.36Å; L572-V577 WeakPolarHBondContact O-CG2 3.36Å; L572-V577 PolarHBondContact O-N 3.38Å
578S95.6Very high95.8Very high43 Ų4345.7 Ų45.730%0.30127%0.272SS..  trans-63.3126.9-175.81790000111.8G576 F580G576-S578 PolarHBondContact O-N 3.36Å; S578-F580 PolarHBondContact O-N 3.01Å; S578-F580 PolarHBondContact OG-N 3.07Å; S578-F580 VanDerWaalsContact OG-N 3.17Å
579P94.8Very high95.7Very high1 Ų145.8 Ų45.81%0.00627%0.272CS..THydrogen-bonded Turntrans-74.9-12.6170.932.1-35.6000113L557 L573 I605 F608 M609L557-P579 HydrophobicContact CD2-CB 4.28Å; L573-P579 HydrophobicContact CD2-CB 3.98Å; L573-P579 HydrophobicContact CD2-CG 4.21Å; P579-I605 HydrophobicContact CB-CG2 3.8Å; P579-F608 HydrophobicContact CG-CD1 4.1Å; P579-F608 HydrophobicContact CG-CE1 4.43Å; P579-M609 HydrophobicContact CB-CG 3.96Å; P579-M609 HydrophobicContact CB-SD 4.3Å; P579-M609 HydrophobicContact CG-CG 3.61Å
580F94.8Very high95.7Very high105 Ų10546.8 Ų46.846%0.46128%0.277SS..THydrogen-bonded Turntrans-87.1-14.3-176.6-55.1-78.3000113.6S578 T582 M609S578-F580 PolarHBondContact O-N 3.01Å; S578-F580 PolarHBondContact OG-N 3.07Å; S578-F580 VanDerWaalsContact OG-N 3.17Å; F580-T582 PolarHBondContact O-N 3.35Å; F580-M609 HydrophobicContact CD1-CE 3.6Å; F580-M609 HydrophobicContact CE1-CB 4.46Å; F580-M609 HydrophobicContact CE1-CE 3.32Å; F580-M609 HydrophobicContact CE1-CG 4.12Å; F580-M609 HydrophobicContact CZ-CB 4.25Å; F580-M609 HydrophobicContact CZ-CE 4.2Å; F580-M609 HydrophobicContact CZ-CG 4.06Å
581S93.4Very high95.6Very high49 Ų4947.4 Ų47.434%0.34328%0.277SS..  trans-62.1130.9175.7-60.70000109.8H558H558-S581 PolarHBondContact CE1-O 3.17Å; H558-S581 PolarHBondContact NE2-O 3.48Å; H558-S581 VanDerWaalsContact NE2-O 3.12Å
582T96.1Very high95.5Very high81 Ų8147.1 Ų47.150%0.49728%0.277SS..BIsolated β-bridgetrans-106.4143176.557.50000110.7F580 H587F580-T582 PolarHBondContact O-N 3.35Å; T582-H587 WeakPolarHBondContact CA-O 3.33Å
583D94.9Very high95.5Very high8 Ų847.1 Ų47.14%0.04328%0.277CS..  trans-67.5173.7166.473.117.2000111.8E552 R554 T585 G586 H587 K592E552-D583 WeakPolarHBondContact O-CB 3.36Å; R554-D583 HydrophobicContact CG-CB 3.75Å; D583-T585 PolarHBondContact O-N 3.26Å; D583-T585 VanDerWaalsContact O-N 3.09Å; D583-T585 VanDerWaalsContact OD1-CA 3.28Å; D583-T585 WeakPolarHBondContact OD1-CA 3.26Å; D583-T585 WeakPolarHBondContact OD1-CB 3.19Å; D583-T585 PolarHBondContact OD1-N 2.93Å; D583-T585 PolarHBondContact OD1-OG1 3.09Å; D583-T585 PolarHBondContact OD2-OG1 3.4Å; D583-G586 PolarHBondContact O-N 3.42Å; D583-G586 PolarHBondContact OD1-N 3.42Å; D583-G586 VanDerWaalsContact OD1-N 3.1Å; D583-H587 PolarHBondContact N-O 3.35Å; D583-H587 PolarHBondContact OD1-N 2.91Å; D583-K592 WeakPolarHBondContact OD2-CE 3.23Å; D583-K592 IonicContact OD2-NZ 3.05Å; D583-K592 PolarHBondContact OD2-NZ 3.47Å
584H94.3Very high95.5Very high148 Ų14849.8 Ų49.869%0.68529%0.291SS*.THydrogen-bonded Turntrans-64.5-12.3179.2-65.8167.8000113.8W551 E552W551-H584 PolarHBondContact O-CE1 3.22Å; W551-H584 PolarHBondContact O-ND1 3.02Å; W551-H584 VanDerWaalsContact O-ND1 3.14Å; E552-H584 WeakPolarHBondContact O-CB 3.34Å; E552-H584 PolarHBondContact O-N 3.43Å
585T93.5Very high95.4Very high96 Ų9649.7 Ų49.759%0.58929%0.29SS*.THydrogen-bonded Turntrans-92.52.5172.966.40000112.8D583 H587D583-T585 PolarHBondContact O-N 3.26Å; D583-T585 VanDerWaalsContact O-N 3.09Å; D583-T585 VanDerWaalsContact OD1-CA 3.28Å; D583-T585 WeakPolarHBondContact OD1-CA 3.26Å; D583-T585 WeakPolarHBondContact OD1-CB 3.19Å; D583-T585 PolarHBondContact OD1-N 2.93Å; D583-T585 PolarHBondContact OD1-OG1 3.09Å; D583-T585 PolarHBondContact OD2-OG1 3.4Å; T585-H587 PolarHBondContact OG1-ND1 3.28Å
586G94.4Very high95.4Very high45 Ų4549.9 Ų49.946%0.46429%0.294SS..SBendtrans81.310.5179.400000114.5D583D583-G586 PolarHBondContact O-N 3.42Å; D583-G586 PolarHBondContact OD1-N 3.42Å; D583-G586 VanDerWaalsContact OD1-N 3.1Å
587H95.7Very high95.4Very high63 Ų6357.4 Ų57.429%0.29231%0.305SS..  trans-93.6128.1179.7-64.4110.5000110.9H558 T582 D583 T585 D591 K592H558-H587 PolarHBondContact NE2-O 2.98Å; H558-H587 VanDerWaalsContact NE2-O 3.15Å; T582-H587 WeakPolarHBondContact CA-O 3.33Å; D583-H587 PolarHBondContact N-O 3.35Å; D583-H587 PolarHBondContact OD1-N 2.91Å; T585-H587 PolarHBondContact OG1-ND1 3.28Å; H587-D591 HydrophobicContact CB-CB 4.03Å; H587-K592 HydrophobicContact CB-CD 4.19Å
588S96.7Very high95.5Very high13 Ų1360.1 Ų60.19%0.09132%0.318CS..BIsolated β-bridgetrans-78.3171.416768.80000111.8L590 D591 K592S588-L590 PolarHBondContact O-N 2.8Å; S588-L590 PolarHBondContact OG-N 3.38Å; S588-D591 WeakPolarHBondContact CB-OD2 3.21Å; S588-D591 PolarHBondContact N-OD2 3.23Å; S588-D591 PolarHBondContact O-N 2.64Å; S588-D591 VanDerWaalsContact O-N 3.12Å; S588-D591 VanDerWaalsContact OG-CG 3.24Å; S588-D591 PolarHBondContact OG-N 3.43Å; S588-D591 PolarHBondContact OG-OD2 3.05Å; S588-K592 PolarHBondContact O-N 3.21Å
589A96.4Very high95.4Very high1 Ų163.7 Ų63.71%0.00833%0.334CS..Hα-helixtrans-59.5-34.5171.400000112.6L557 A561 K592 A593 I605L557-A589 HydrophobicContact CB-CB 4.39Å; L557-A589 HydrophobicContact CD2-CB 3.93Å; L557-A589 HydrophobicContact CG-CB 3.64Å; A561-A589 HydrophobicContact CB-CB 4.16Å; A561-A589 WeakPolarHBondContact CB-O 3.34Å; A589-K592 PolarHBondContact O-N 3.01Å; A589-A593 PolarHBondContact O-N 2.96Å; A589-I605 HydrophobicContact CB-CD1 4.22Å
590L96.9Very high95.5Very high22 Ų2264.5 Ų64.512%0.11534%0.343CS..Hα-helixtrans-62.9-44.1174.1178.257.9000111S588 K592 A593 L594 A602 I605 R606 M609S588-L590 PolarHBondContact O-N 2.8Å; S588-L590 PolarHBondContact OG-N 3.38Å; L590-K592 VanDerWaalsContact C-N 3.31Å; L590-K592 PolarHBondContact O-N 2.98Å; L590-A593 PolarHBondContact O-N 3.32Å; L590-L594 HydrophobicContact CD1-CD1 4.13Å; L590-L594 HydrophobicContact CD1-CG 4.21Å; L590-L594 HydrophobicContact CG-CD1 4.04Å; L590-L594 WeakPolarHBondContact O-CG 3.33Å; L590-L594 PolarHBondContact O-N 3.38Å; L590-A602 HydrophobicContact CD1-CB 3.81Å; L590-I605 HydrophobicContact CB-CG2 3.86Å; L590-I605 HydrophobicContact CD1-CB 4.36Å; L590-I605 HydrophobicContact CD1-CG2 4.37Å; L590-R606 HydrophobicContact CD1-CG 3.94Å; L590-R606 HydrophobicContact CD2-CG 3.92Å; L590-M609 HydrophobicContact CD2-SD 4.03Å
591D96.8Very high95.5Very high57 Ų5759.5 Ų59.531%0.30532%0.321SS..Hα-helixtrans-62.5-41178.6-58.2-49.8000111H587 S588 L594 L595H587-D591 HydrophobicContact CB-CB 4.03Å; S588-D591 WeakPolarHBondContact CB-OD2 3.21Å; S588-D591 PolarHBondContact N-OD2 3.23Å; S588-D591 PolarHBondContact O-N 2.64Å; S588-D591 VanDerWaalsContact O-N 3.12Å; S588-D591 VanDerWaalsContact OG-CG 3.24Å; S588-D591 PolarHBondContact OG-N 3.43Å; S588-D591 PolarHBondContact OG-OD2 3.05Å; D591-L594 PolarHBondContact O-N 2.86Å; D591-L595 WeakPolarHBondContact O-CB 3.2Å; D591-L595 WeakPolarHBondContact O-CG 3.39Å; D591-L595 PolarHBondContact O-N 3.29Å
592K95.8Very high95.7Very high38 Ų3857.2 Ų57.217%0.16530%0.304CS..Hα-helixtrans-60.7-44.9174.2-63.1-56.7-174.6-167.10112.4D583 H587 S588 A589 L590 L594 L595 S596D583-K592 WeakPolarHBondContact OD2-CE 3.23Å; D583-K592 IonicContact OD2-NZ 3.05Å; D583-K592 PolarHBondContact OD2-NZ 3.47Å; H587-K592 HydrophobicContact CB-CD 4.19Å; S588-K592 PolarHBondContact O-N 3.21Å; A589-K592 PolarHBondContact O-N 3.01Å; L590-K592 VanDerWaalsContact C-N 3.31Å; L590-K592 PolarHBondContact O-N 2.98Å; K592-L594 VanDerWaalsContact C-N 3.32Å; K592-L594 PolarHBondContact O-N 3.38Å; K592-L595 PolarHBondContact O-N 3.45Å; K592-S596 WeakPolarHBondContact O-CB 3.3Å; K592-S596 PolarHBondContact O-N 3.35Å; K592-S596 PolarHBondContact O-OG 3.46Å
593A96.8Very high95.7Very high0 Ų059.5 Ų59.50%031%0.307CS..Hα-helixtrans-60.9-41.2176.600000112.2A561 A589 L590 R597 H598 C601 A602 I605A561-A593 HydrophobicContact CB-CB 4.1Å; A561-A593 WeakPolarHBondContact O-CA 3.46Å; A589-A593 PolarHBondContact O-N 2.96Å; L590-A593 PolarHBondContact O-N 3.32Å; A593-R597 PolarHBondContact O-N 3.04Å; A593-R597 VanDerWaalsContact O-N 3.12Å; A593-H598 PolarHBondContact O-N 3.48Å; A593-C601 HydrophobicContact CB-CB 3.98Å; A593-A602 HydrophobicContact CB-CB 4Å; A593-I605 HydrophobicContact CB-CD1 4.5Å
594L96.5Very high95.8Very high61 Ų6161.4 Ų61.432%0.31932%0.318SS..Hα-helixtrans-70.5-43.9179.6-66.8172.5000112.3L590 D591 K592 S596 R597 A602L590-L594 HydrophobicContact CD1-CD1 4.13Å; L590-L594 HydrophobicContact CD1-CG 4.21Å; L590-L594 HydrophobicContact CG-CD1 4.04Å; L590-L594 WeakPolarHBondContact O-CG 3.33Å; L590-L594 PolarHBondContact O-N 3.38Å; D591-L594 PolarHBondContact O-N 2.86Å; K592-L594 VanDerWaalsContact C-N 3.32Å; K592-L594 PolarHBondContact O-N 3.38Å; L594-S596 VanDerWaalsContact C-N 3.31Å; L594-S596 PolarHBondContact O-N 3.05Å; L594-R597 PolarHBondContact O-N 3.19Å; L594-R597 VanDerWaalsContact O-N 3.09Å; L594-A602 HydrophobicContact CD2-CB 3.67Å; L594-A602 HydrophobicContact CG-CB 4.17Å
595L94.6Very high95.9Very high112 Ų11254.4 Ų54.459%0.58629%0.285SS*.Hα-helixtrans-59.7-41.4176.7-73.9169.2000111.6D591 K592 R597D591-L595 WeakPolarHBondContact O-CB 3.2Å; D591-L595 WeakPolarHBondContact O-CG 3.39Å; D591-L595 PolarHBondContact O-N 3.29Å; K592-L595 PolarHBondContact O-N 3.45Å; L595-R597 VanDerWaalsContact C-N 3.3Å; L595-R597 PolarHBondContact O-N 3.01Å
596S94.6Very high96Very high47 Ų4755.7 Ų55.733%0.32928%0.279SS..THydrogen-bonded Turntrans-83.21.4176.8-62.50000114.3S562 K592 L594 H598S562-S596 WeakPolarHBondContact O-CB 3.36Å; S562-S596 PolarHBondContact O-OG 3.36Å; S562-S596 VanDerWaalsContact O-OG 3.12Å; K592-S596 WeakPolarHBondContact O-CB 3.3Å; K592-S596 PolarHBondContact O-N 3.35Å; K592-S596 PolarHBondContact O-OG 3.46Å; L594-S596 VanDerWaalsContact C-N 3.31Å; L594-S596 PolarHBondContact O-N 3.05Å; S596-H598 VanDerWaalsContact C-N 3.3Å; S596-H598 WeakPolarHBondContact CB-CD2 3.39Å; S596-H598 PolarHBondContact O-N 2.97Å
597R95.6Very high96Very high214 Ų21458.1 Ų58.181%0.80828%0.278SS*.THydrogen-bonded Turntrans61.727.4-179.5-51.9-179.9179.3-174.9-0.8115A593 L594 L595 N599A593-R597 PolarHBondContact O-N 3.04Å; A593-R597 VanDerWaalsContact O-N 3.12Å; L594-R597 PolarHBondContact O-N 3.19Å; L594-R597 VanDerWaalsContact O-N 3.09Å; L595-R597 VanDerWaalsContact C-N 3.3Å; L595-R597 PolarHBondContact O-N 3.01Å; R597-N599 PolarHBondContact O-N 2.97Å; R597-N599 VanDerWaalsContact O-N 3.15Å
598H97.1Very high96Very high59 Ų5957 Ų5727%0.27327%0.273SS..  trans-8677.3174.2-62.5-57.2000111.1A561 S562 V563 G564 A593 S596 G600 C601 A602A561-H598 PolarHBondContact O-CD2 3.1Å; S562-H598 PolarHBondContact O-CD2 3.36Å; S562-H598 PolarHBondContact O-NE2 3.31Å; V563-H598 VanDerWaalsContact C-NE2 3.28Å; V563-H598 PolarHBondContact O-CE1 3.23Å; V563-H598 VanDerWaalsContact O-CE1 3.28Å; V563-H598 PolarHBondContact O-NE2 2.75Å; G564-H598 WeakPolarHBondContact CA-ND1 3.31Å; G564-H598 PolarHBondContact N-CD2 3.07Å; A593-H598 PolarHBondContact O-N 3.48Å; S596-H598 VanDerWaalsContact C-N 3.3Å; S596-H598 WeakPolarHBondContact CB-CD2 3.39Å; S596-H598 PolarHBondContact O-N 2.97Å; H598-G600 VanDerWaalsContact C-N 3.29Å; H598-G600 PolarHBondContact O-N 3.32Å; H598-C601 HydrophobicContact CB-CB 4.26Å; H598-C601 PolarHBondContact O-N 3.32Å; H598-A602 PolarHBondContact O-N 3.41Å; H598-A602 VanDerWaalsContact O-N 3.08Å
599N94.5Very high95.8Very high117 Ų11758.5 Ų58.563%0.62628%0.279SS*.Hα-helixtrans-60.9-32-174.1-70.8-39.7000114.3R597 A602 K603R597-N599 PolarHBondContact O-N 2.97Å; R597-N599 VanDerWaalsContact O-N 3.15Å; N599-A602 PolarHBondContact O-N 3.44Å; N599-K603 WeakPolarHBondContact O-CB 3.45Å; N599-K603 PolarHBondContact O-N 3.08Å
600G95.3Very high95.6Very high19 Ų1960.9 Ų60.920%0.19630%0.299CS..Hα-helixtrans-65.8-49.117700000112.2E566 H598 A602 K603 L604E566-G600 WeakPolarHBondContact OE1-CA 3.35Å; H598-G600 VanDerWaalsContact C-N 3.29Å; H598-G600 PolarHBondContact O-N 3.32Å; G600-A602 VanDerWaalsContact C-N 3.34Å; G600-A602 PolarHBondContact O-N 3.3Å; G600-K603 WeakPolarHBondContact O-CB 3.27Å; G600-K603 PolarHBondContact O-N 2.95Å; G600-K603 VanDerWaalsContact O-N 3.15Å; G600-L604 WeakPolarHBondContact O-CG 3.29Å; G600-L604 PolarHBondContact O-N 3.32Å
601C96.2Very high95.2Very high0 Ų064.7 Ų64.70%032%0.319CS..Hα-helixtrans-57.1-46.2172.1-65.60000111.9V569 A593 H598 K603 L604 I605V569-C601 HydrophobicContact CG2-CB 4.23Å; A593-C601 HydrophobicContact CB-CB 3.98Å; H598-C601 HydrophobicContact CB-CB 4.26Å; H598-C601 PolarHBondContact O-N 3.32Å; C601-K603 VanDerWaalsContact C-N 3.28Å; C601-K603 PolarHBondContact O-N 3.45Å; C601-L604 PolarHBondContact O-N 3.43Å; C601-I605 VanDerWaalsContact O-CG1 3.3Å; C601-I605 WeakPolarHBondContact O-CG1 3.44Å; C601-I605 PolarHBondContact O-N 3.38Å
602A96.6Very high94.6Very high0 Ų065.8 Ų65.80%032%0.322CS..Hα-helixtrans-61.8-36.5178.700000112.4L590 A593 L594 H598 N599 G600 R606L590-A602 HydrophobicContact CD1-CB 3.81Å; A593-A602 HydrophobicContact CB-CB 4Å; L594-A602 HydrophobicContact CD2-CB 3.67Å; L594-A602 HydrophobicContact CG-CB 4.17Å; H598-A602 PolarHBondContact O-N 3.41Å; H598-A602 VanDerWaalsContact O-N 3.08Å; N599-A602 PolarHBondContact O-N 3.44Å; G600-A602 VanDerWaalsContact C-N 3.34Å; G600-A602 PolarHBondContact O-N 3.3Å; A602-R606 WeakPolarHBondContact O-CB 3.49Å; A602-R606 VanDerWaalsContact O-CG 3.27Å; A602-R606 WeakPolarHBondContact O-CG 3.36Å; A602-R606 PolarHBondContact O-N 3.49Å
603K96.7Very high93.7Very high129 Ų12967.3 Ų67.356%0.56134%0.342SS*.Hα-helixtrans-65.4-47.9174.9-176.6-176.3176-172.90111.2N599 G600 C601 I605 R606 Q607N599-K603 WeakPolarHBondContact O-CB 3.45Å; N599-K603 PolarHBondContact O-N 3.08Å; G600-K603 WeakPolarHBondContact O-CB 3.27Å; G600-K603 PolarHBondContact O-N 2.95Å; G600-K603 VanDerWaalsContact O-N 3.15Å; C601-K603 VanDerWaalsContact C-N 3.28Å; C601-K603 PolarHBondContact O-N 3.45Å; K603-I605 PolarHBondContact O-N 3.05Å; K603-R606 PolarHBondContact O-N 3.49Å; K603-Q607 WeakPolarHBondContact O-CB 3.49Å; K603-Q607 VanDerWaalsContact O-CG 3.29Å; K603-Q607 WeakPolarHBondContact O-CG 3.33Å; K603-Q607 PolarHBondContact O-N 3.25Å
604L96.4Very high92.8Very high49 Ų4973.8 Ų73.826%0.25738%0.376SS..Hα-helixtrans-58.7-47.7178-70.2172.7000111.6E566 V569 G600 C601 R606 Q607 F608E566-L604 HydrophobicContact CB-CD1 3.9Å; E566-L604 HydrophobicContact CG-CD1 4.44Å; E566-L604 WeakPolarHBondContact O-CD1 3.39Å; V569-L604 HydrophobicContact CG1-CB 4.25Å; G600-L604 WeakPolarHBondContact O-CG 3.29Å; G600-L604 PolarHBondContact O-N 3.32Å; C601-L604 PolarHBondContact O-N 3.43Å; L604-R606 PolarHBondContact O-N 2.96Å; L604-Q607 PolarHBondContact O-N 2.99Å; L604-F608 PolarHBondContact O-N 3.36Å
605I96.1Very high91.4Very high0 Ų075.6 Ų75.60%039%0.394CS..Hα-helixtrans-62.9-45.7179.7-64.3164.7000110.9A561 V569 L573 P579 A589 L590 A593 C601 K603 Q607 F608 M609A561-I605 HydrophobicContact CB-CD1 4.01Å; V569-I605 HydrophobicContact CG1-CD1 4.12Å; V569-I605 HydrophobicContact CG1-CG1 3.67Å; L573-I605 HydrophobicContact CD1-CG1 4.12Å; P579-I605 HydrophobicContact CB-CG2 3.8Å; A589-I605 HydrophobicContact CB-CD1 4.22Å; L590-I605 HydrophobicContact CB-CG2 3.86Å; L590-I605 HydrophobicContact CD1-CB 4.36Å; L590-I605 HydrophobicContact CD1-CG2 4.37Å; A593-I605 HydrophobicContact CB-CD1 4.5Å; C601-I605 VanDerWaalsContact O-CG1 3.3Å; C601-I605 WeakPolarHBondContact O-CG1 3.44Å; C601-I605 PolarHBondContact O-N 3.38Å; K603-I605 PolarHBondContact O-N 3.05Å; I605-Q607 PolarHBondContact O-N 2.92Å; I605-F608 PolarHBondContact O-N 3.15Å; I605-M609 HydrophobicContact CG2-CG 4.28Å; I605-M609 HydrophobicContact CG2-SD 3.75Å; I605-M609 VanDerWaalsContact O-CG 3.26Å; I605-M609 WeakPolarHBondContact O-CG 3.37Å; I605-M609 PolarHBondContact O-N 3.48Å
606R96.1Very high89.3Confident123 Ų12379.8 Ų79.846%0.46442%0.417SS..Hα-helixtrans-61-42.7176.7-78.1177.2-179.3135.1-3.3112.6L590 A602 K603 L604 F608 M609 A610L590-R606 HydrophobicContact CD1-CG 3.94Å; L590-R606 HydrophobicContact CD2-CG 3.92Å; A602-R606 WeakPolarHBondContact O-CB 3.49Å; A602-R606 VanDerWaalsContact O-CG 3.27Å; A602-R606 WeakPolarHBondContact O-CG 3.36Å; A602-R606 PolarHBondContact O-N 3.49Å; K603-R606 PolarHBondContact O-N 3.49Å; L604-R606 PolarHBondContact O-N 2.96Å; R606-F608 VanDerWaalsContact C-N 3.34Å; R606-M609 PolarHBondContact O-N 3.09Å; R606-A610 WeakPolarHBondContact O-CB 3.43Å; R606-A610 PolarHBondContact O-N 3.43Å
607Q94.4Very high89Confident96 Ų9681.5 Ų81.545%0.44942%0.422SS..Hα-helixtrans-61.3-44.8177.4-76.1177.2-30.400110.8K603 L604 I605 A610 N611K603-Q607 WeakPolarHBondContact O-CB 3.49Å; K603-Q607 VanDerWaalsContact O-CG 3.29Å; K603-Q607 WeakPolarHBondContact O-CG 3.33Å; K603-Q607 PolarHBondContact O-N 3.25Å; L604-Q607 PolarHBondContact O-N 2.99Å; I605-Q607 PolarHBondContact O-N 2.92Å; Q607-A610 PolarHBondContact O-N 3.28Å; Q607-N611 PolarHBondContact O-N 3.43Å; Q607-N611 PolarHBondContact O-ND2 3.48Å
608F95Very high88.7Confident40 Ų4074.5 Ų74.518%0.17540%0.402CS..Hα-helixtrans-62.8-46.7176.5-171.5-86.9000112.4L573 P579 L604 I605 R606 A610 N611 Q612L573-F608 HydrophobicContact CB-CD1 4.42Å; L573-F608 HydrophobicContact CB-CD2 3.72Å; L573-F608 HydrophobicContact CB-CE2 3.83Å; L573-F608 HydrophobicContact CB-CG 4.02Å; L573-F608 HydrophobicContact CB-CZ 4.22Å; L573-F608 HydrophobicContact CD1-CB 3.93Å; L573-F608 HydrophobicContact CD1-CD2 4.47Å; L573-F608 HydrophobicContact CD1-CG 4.15Å; L573-F608 HydrophobicContact CD2-CB 4.48Å; L573-F608 HydrophobicContact CD2-CD1 3.87Å; L573-F608 HydrophobicContact CD2-CE1 4.21Å; L573-F608 HydrophobicContact CD2-CG 4.08Å; L573-F608 HydrophobicContact CG-CD2 4.49Å; L573-F608 HydrophobicContact CG-CG 4.31Å; L573-F608 WeakPolarHBondContact O-CE2 3.41Å; L573-F608 WeakPolarHBondContact O-CZ 3.15Å; P579-F608 HydrophobicContact CG-CD1 4.1Å; P579-F608 HydrophobicContact CG-CE1 4.43Å; L604-F608 PolarHBondContact O-N 3.36Å; I605-F608 PolarHBondContact O-N 3.15Å; R606-F608 VanDerWaalsContact C-N 3.34Å; F608-A610 VanDerWaalsContact C-N 3.34Å; F608-A610 PolarHBondContact O-N 3.08Å; F608-N611 PolarHBondContact O-N 3.41Å; F608-Q612 HydrophobicContact CD1-CG 4.38Å; F608-Q612 HydrophobicContact CE1-CG 4.01Å; F608-Q612 PolarHBondContact O-N 3.48Å; F608-Q612 VanDerWaalsContact O-N 3.09Å
609M93.4Very high88.2Confident45 Ų4575.3 Ų75.322%0.22241%0.409CS..Hα-helixtrans-59.8-41.5176.8-68.8170.682.900112.2P579 F580 L590 I605 R606 Q612 A613P579-M609 HydrophobicContact CB-CG 3.96Å; P579-M609 HydrophobicContact CB-SD 4.3Å; P579-M609 HydrophobicContact CG-CG 3.61Å; F580-M609 HydrophobicContact CD1-CE 3.6Å; F580-M609 HydrophobicContact CE1-CB 4.46Å; F580-M609 HydrophobicContact CE1-CE 3.32Å; F580-M609 HydrophobicContact CE1-CG 4.12Å; F580-M609 HydrophobicContact CZ-CB 4.25Å; F580-M609 HydrophobicContact CZ-CE 4.2Å; F580-M609 HydrophobicContact CZ-CG 4.06Å; L590-M609 HydrophobicContact CD2-SD 4.03Å; I605-M609 HydrophobicContact CG2-CG 4.28Å; I605-M609 HydrophobicContact CG2-SD 3.75Å; I605-M609 VanDerWaalsContact O-CG 3.26Å; I605-M609 WeakPolarHBondContact O-CG 3.37Å; I605-M609 PolarHBondContact O-N 3.48Å; R606-M609 PolarHBondContact O-N 3.09Å; M609-Q612 PolarHBondContact O-N 3.12Å; M609-A613 PolarHBondContact O-N 3.38Å
610A92.2Very high87.8Confident51 Ų5172.9 Ų72.942%0.42140%0.396SS..Hα-helixtrans-66.6-36.4177.200000112.6R606 Q607 F608 A613 N614R606-A610 WeakPolarHBondContact O-CB 3.43Å; R606-A610 PolarHBondContact O-N 3.43Å; Q607-A610 PolarHBondContact O-N 3.28Å; F608-A610 VanDerWaalsContact C-N 3.34Å; F608-A610 PolarHBondContact O-N 3.08Å; A610-A613 PolarHBondContact O-N 3.38Å; A610-N614 PolarHBondContact O-N 3.37Å; A610-N614 PolarHBondContact O-ND2 3.31Å
611N89.4Confident87.4Confident102 Ų10276.3 Ų76.355%0.54541%0.408SS..Hα-helixtrans-67.6-38.5176.4-70.3-14.8000112Q607 F608 N614 S615Q607-N611 PolarHBondContact O-N 3.43Å; Q607-N611 PolarHBondContact O-ND2 3.48Å; F608-N611 PolarHBondContact O-N 3.41Å; N611-N614 PolarHBondContact O-N 2.85Å; N611-S615 PolarHBondContact O-N 3.13Å; N611-S615 PolarHBondContact O-OG 3.28Å
612Q82.3Confident86.8Confident80 Ų8081.3 Ų81.337%0.37444%0.436SS..Hα-helixtrans-65.1-42.2174.9-73.7-155.3-21.200112.2F608 M609 N614 S615 D616F608-Q612 HydrophobicContact CD1-CG 4.38Å; F608-Q612 HydrophobicContact CE1-CG 4.01Å; F608-Q612 PolarHBondContact O-N 3.48Å; F608-Q612 VanDerWaalsContact O-N 3.09Å; M609-Q612 PolarHBondContact O-N 3.12Å; Q612-N614 PolarHBondContact O-N 3.12Å; Q612-N614 VanDerWaalsContact O-N 3.15Å; Q612-S615 WeakPolarHBondContact O-CB 3.39Å; Q612-S615 PolarHBondContact O-N 3.23Å; Q612-D616 PolarHBondContact O-N 3.15Å
613A78.9Confident86.1Confident69 Ų6987.1 Ų87.157%0.5747%0.467SS*.Hα-helixtrans-63.5-19.6177.600000114.4M609 A610M609-A613 PolarHBondContact O-N 3.38Å; A610-A613 PolarHBondContact O-N 3.38Å
614N76.1Confident85.2Confident136 Ų13683.9 Ų83.973%0.72746%0.46SS*.THydrogen-bonded Turntrans-92.3-7.8174.4-69.1-31.8000113.2A610 N611 Q612A610-N614 PolarHBondContact O-N 3.37Å; A610-N614 PolarHBondContact O-ND2 3.31Å; N611-N614 PolarHBondContact O-N 2.85Å; Q612-N614 PolarHBondContact O-N 3.12Å; Q612-N614 VanDerWaalsContact O-N 3.15Å
615S67.8Low84.3Confident100 Ų10086.8 Ų86.870%0.69948%0.476SS*.THydrogen-bonded Turntrans-99-16.9-177.2-52.90000112.9N611 Q612N611-S615 PolarHBondContact O-N 3.13Å; N611-S615 PolarHBondContact O-OG 3.28Å; Q612-S615 WeakPolarHBondContact O-CB 3.39Å; Q612-S615 PolarHBondContact O-N 3.23Å
616D49.9Very low83.2Confident200 Ų20094.7 Ų94.7100%1.0752%0.52SS*.  trans-93.10169.4-66-27.8000110.4Q612Q612-D616 PolarHBondContact O-N 3.15Å

Retrieved 616 of 616 residues in 561.6 ms (Link to these results)