A0A077Z9P8_TRITR Loading...

PH domain-containing protein

AlphaFold DB , UniProt , Accession A0A077Z9P8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 832 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.8Very low38.4Very low219 Ų219130.9 Ų130.9100%1.07965%0.652SS**  0104.40-91.8173.268.300106.6V3M1-V3 HydrophobicContact CB-CG2 4.36Å; M1-V3 HydrophobicContact CE-CG2 4.21Å; M1-V3 PolarHBondContact O-N 3.23Å
2E30.7Very low39.7Very low203 Ų203124.8 Ų124.895%0.94964%0.637SS**  trans-71.6103.9157.7-77.6-179.5163.100105.5D4E2-D4 PolarHBondContact O-N 2.94Å
3V35.9Very low41.8Very low85 Ų85121.8 Ų121.852%0.51563%0.628SS.*  trans-75.9108.7173.8-178.70000105.3M1 P5 F8M1-V3 HydrophobicContact CB-CG2 4.36Å; M1-V3 HydrophobicContact CE-CG2 4.21Å; M1-V3 PolarHBondContact O-N 3.23Å; V3-P5 VanDerWaalsContact O-CD 3.31Å; V3-P5 WeakPolarHBondContact O-CD 3.42Å; V3-P5 VanDerWaalsContact O-N 3.15Å; V3-F8 HydrophobicContact CG1-CD2 4.3Å; V3-F8 HydrophobicContact CG1-CE2 4.08Å
4D37.3Very low43.9Very low98 Ų98118.1 Ų118.152%0.52461%0.613SS.*  trans-50.8118165177.65.9000107.9E2 E6 P7E2-D4 PolarHBondContact O-N 2.94Å; D4-E6 PolarHBondContact O-N 3.49Å; D4-E6 VanDerWaalsContact OD1-CB 3.27Å; D4-E6 WeakPolarHBondContact OD1-CB 3.4Å; D4-E6 PolarHBondContact OD1-N 3.11Å; D4-P7 WeakPolarHBondContact O-CD 3.37Å
5P38.5Very low46.1Very low78 Ų78118.1 Ų118.151%0.50661%0.607SS.*SBendtrans-74.8-9.8-178.329.3-33.4000112.7V3 P7 F8 L9V3-P5 VanDerWaalsContact O-CD 3.31Å; V3-P5 WeakPolarHBondContact O-CD 3.42Å; V3-P5 VanDerWaalsContact O-N 3.15Å; P5-P7 VanDerWaalsContact C-CD 3.44Å; P5-F8 WeakPolarHBondContact O-CA 3.33Å; P5-F8 WeakPolarHBondContact O-CB 3.46Å; P5-F8 PolarHBondContact O-N 3.2Å; P5-L9 PolarHBondContact O-N 3.12Å
6E38.9Very low48.7Very low108 Ų108113.1 Ų113.151%0.50558%0.579SS.*Hα-helixtrans-55.6-38.7-176.7-151-161.8-132.400114.3D4 L9 K10D4-E6 PolarHBondContact O-N 3.49Å; D4-E6 VanDerWaalsContact OD1-CB 3.27Å; D4-E6 WeakPolarHBondContact OD1-CB 3.4Å; D4-E6 PolarHBondContact OD1-N 3.11Å; E6-L9 PolarHBondContact O-N 3.05Å; E6-K10 WeakPolarHBondContact O-CG 3.49Å; E6-K10 PolarHBondContact O-N 3.5Å; E6-K10 VanDerWaalsContact O-N 3.08Å; E6-K10 IonicContact OE2-NZ 3.01Å; E6-K10 PolarHBondContact OE2-NZ 3.49Å
7P38.5Very low51.2Low69 Ų69111.8 Ų111.845%0.44857%0.57SS.*Hα-helixtrans-68.8-31.5172.9-17.832.9000113.7D4 P5 K10 F11D4-P7 WeakPolarHBondContact O-CD 3.37Å; P5-P7 VanDerWaalsContact C-CD 3.44Å; P7-K10 PolarHBondContact O-N 3.33Å; P7-F11 WeakPolarHBondContact O-CD2 3.38Å
8F37.6Very low53.4Low156 Ų156107.2 Ų107.268%0.68455%0.55SS*.Hα-helixtrans-71.9-38.3174.6-86.5-87.5000111.1V3 P5 K10 F11V3-F8 HydrophobicContact CG1-CD2 4.3Å; V3-F8 HydrophobicContact CG1-CE2 4.08Å; P5-F8 WeakPolarHBondContact O-CA 3.33Å; P5-F8 WeakPolarHBondContact O-CB 3.46Å; P5-F8 PolarHBondContact O-N 3.2Å; F8-K10 VanDerWaalsContact C-N 3.28Å; F8-K10 PolarHBondContact O-N 3.14Å; F8-F11 PolarHBondContact O-N 3.29Å
9L40Very low55.4Low121 Ų121105.5 Ų105.563%0.63454%0.54SS*.Hα-helixtrans-66.5-28.4174-69.6168.4000112.3P5 E6 F11 A12P5-L9 PolarHBondContact O-N 3.12Å; E6-L9 PolarHBondContact O-N 3.05Å; L9-F11 PolarHBondContact O-N 3.37Å; L9-A12 WeakPolarHBondContact O-CB 3.32Å; L9-A12 PolarHBondContact O-N 3.41Å; L9-A12 VanDerWaalsContact O-N 3.1Å
10K43.2Very low57.3Low133 Ų133100.3 Ų100.358%0.57851%0.513SS*.THydrogen-bonded Turntrans-66.6-14.8172.4-78.7173.5-175.5158.20114.4E6 P7 F8 A12 V13E6-K10 WeakPolarHBondContact O-CG 3.49Å; E6-K10 PolarHBondContact O-N 3.5Å; E6-K10 VanDerWaalsContact O-N 3.08Å; E6-K10 IonicContact OE2-NZ 3.01Å; E6-K10 PolarHBondContact OE2-NZ 3.49Å; P7-K10 PolarHBondContact O-N 3.33Å; F8-K10 VanDerWaalsContact C-N 3.28Å; F8-K10 PolarHBondContact O-N 3.14Å; K10-A12 VanDerWaalsContact C-N 3.3Å; K10-V13 WeakPolarHBondContact O-CG2 3.33Å
11F46.8Very low58.9Low170 Ų17096.6 Ų96.675%0.74650%0.495SS*.THydrogen-bonded Turntrans-76.8-17.2170.7-81.1-84.1000113P7 F8 L9 V13P7-F11 WeakPolarHBondContact O-CD2 3.38Å; F8-F11 PolarHBondContact O-N 3.29Å; L9-F11 PolarHBondContact O-N 3.37Å; F11-V13 PolarHBondContact O-N 2.95Å
12A53.7Low61.5Low58 Ų5886.2 Ų86.248%0.47944%0.444SS..  trans-79.949.917200000111.6L9 K10 V53L9-A12 WeakPolarHBondContact O-CB 3.32Å; L9-A12 PolarHBondContact O-N 3.41Å; L9-A12 VanDerWaalsContact O-N 3.1Å; K10-A12 VanDerWaalsContact C-N 3.3Å; A12-V53 HydrophobicContact CB-CG1 3.69Å
13V67.4Low64.1Low85 Ų8577.3 Ų77.352%0.51540%0.401SS..  trans-74.5129.2171.9-170.90000108.4K10 F11 K15K10-V13 WeakPolarHBondContact O-CG2 3.33Å; F11-V13 PolarHBondContact O-N 2.95Å; V13-K15 PolarHBondContact O-N 3.42Å; V13-K15 VanDerWaalsContact O-N 3.12Å
14V71.6Confident66.1Low70 Ų7077.3 Ų77.342%0.42439%0.394SS..EExtended strand (participates in β ladder)trans-60.8113.9167.7178.20000108.4E17 T51 L52 V53V14-E17 HydrophobicContact CG1-CB 3.9Å; V14-T51 HydrophobicContact CB-CG2 4.35Å; V14-T51 HydrophobicContact CG1-CG2 3.65Å; V14-T51 HydrophobicContact CG2-CG2 3.82Å; V14-L52 CarbonylContact C-O 3.55Å; V14-L52 WeakPolarHBondContact CA-O 3.37Å; V14-V53 HydrophobicContact CG2-CG2 4.11Å
15K77Confident67.9Low118 Ų11878.8 Ų78.851%0.51340%0.396SS..EExtended strand (participates in β ladder)trans-81.7-36.1-179.4-69-76.1-175.4177.80112V13 L52 C124V13-K15 PolarHBondContact O-N 3.42Å; V13-K15 VanDerWaalsContact O-N 3.12Å; K15-L52 HydrophobicContact CB-CB 4.41Å; K15-L52 HydrophobicContact CB-CD2 4.14Å; K15-L52 HydrophobicContact CB-CG 4.07Å; K15-L52 PolarHBondContact N-O 3.28Å; K15-C124 VanDerWaalsContact CG-SG 3.6Å
16K87.8Confident68.9Low38 Ų3876.4 Ų76.417%0.16538%0.379CS..EExtended strand (participates in β ladder)trans-159.2142.8173.7-167.7167.7173.1760109L52 D116 W117 A120K16-L52 PolarHBondContact O-N 3.35Å; K16-D116 IonicContact NZ-OD2 2.71Å; K16-W117 HydrophobicContact CB-CH2 4.38Å; K16-W117 HydrophobicContact CB-CZ3 4.41Å; K16-W117 HydrophobicContact CD-CD2 3.74Å; K16-W117 HydrophobicContact CD-CE3 4.12Å; K16-W117 HydrophobicContact CD-CG 3.98Å; K16-W117 HydrophobicContact CD-CZ2 4.4Å; K16-W117 VanDerWaalsContact CE-CG 3.5Å; K16-W117 HydrophobicContact CG-CD2 4.33Å; K16-W117 HydrophobicContact CG-CH2 4.34Å; K16-W117 HydrophobicContact CG-CZ2 4.12Å; K16-A120 HydrophobicContact CB-CB 4.16Å; K16-A120 HydrophobicContact CD-CB 3.93Å
17E90Very high69.7Low91 Ų9175.4 Ų75.443%0.42538%0.376SS..EExtended strand (participates in β ladder)trans-140.3132.3173.4-178.5174.5-176.300109V14 R49 A50 T51V14-E17 HydrophobicContact CG1-CB 3.9Å; E17-R49 HydrophobicContact CG-CG 4.38Å; E17-R49 VanDerWaalsContact OE1-CD 3.31Å; E17-R49 WeakPolarHBondContact OE1-CD 3.16Å; E17-R49 IonicContact OE1-CZ 3.67Å; E17-R49 IonicContact OE1-NE 3.91Å; E17-R49 IonicContact OE1-NH1 3.84Å; E17-R49 PolarHBondContact OE1-NH1 3.02Å; E17-A50 VanDerWaalsContact CA-O 3.25Å; E17-A50 WeakPolarHBondContact CA-O 3.41Å; E17-T51 HydrophobicContact CB-CG2 4.3Å; E17-T51 HydrophobicContact CG-CG2 4.35Å
18S91.6Very high70.5Confident29 Ų2974.3 Ų74.320%0.20337%0.365CS..EExtended strand (participates in β ladder)trans-165.5173.5171.464.30000111.2A50 W117S18-A50 PolarHBondContact N-O 3.06Å; S18-A50 PolarHBondContact O-N 2.81Å; S18-W117 VanDerWaalsContact OG-CE2 3.25Å; S18-W117 WeakPolarHBondContact OG-CZ2 3.34Å; S18-W117 PolarHBondContact OG-NE1 3.49Å
19M91.7Very high71.1Confident76 Ų7672.6 Ų72.637%0.37436%0.363SS..EExtended strand (participates in β ladder)trans-80.8130.1171.1-62.6-62.5-75.700110T47 V48 R49 V62 F109M19-T47 HydrophobicContact CE-CG2 3.38Å; M19-V48 WeakPolarHBondContact CA-O 3.35Å; M19-R49 HydrophobicContact SD-CB 3.66Å; M19-R49 HydrophobicContact SD-CG 4.17Å; M19-V62 HydrophobicContact CE-CB 3.98Å; M19-V62 HydrophobicContact CE-CG1 4.04Å; M19-V62 HydrophobicContact CE-CG2 3.51Å; M19-V62 HydrophobicContact SD-CG2 4.06Å; M19-F109 HydrophobicContact CB-CD2 4.31Å; M19-F109 HydrophobicContact CB-CE2 3.93Å
20L93Very high71.6Confident0 Ų072.8 Ų72.80%036%0.36CS..EExtended strand (participates in β ladder)trans-125.2151.6176.2-65.8-179.2000110.1V48 A50 M57 F95 F106 W117L20-V48 HydrophobicContact CB-CG2 4.1Å; L20-V48 PolarHBondContact N-O 2.96Å; L20-V48 WeakPolarHBondContact O-CG2 3.3Å; L20-V48 PolarHBondContact O-N 3.44Å; L20-V48 VanDerWaalsContact O-O 3.13Å; L20-A50 HydrophobicContact CD1-CB 3.51Å; L20-A50 HydrophobicContact CG-CB 4.01Å; L20-M57 HydrophobicContact CD1-CE 4.08Å; L20-F95 HydrophobicContact CD1-CE1 4.28Å; L20-F95 HydrophobicContact CD1-CZ 3.85Å; L20-F95 HydrophobicContact CD2-CE1 4.04Å; L20-F95 HydrophobicContact CD2-CZ 4.43Å; L20-F106 HydrophobicContact CB-CD1 4.36Å; L20-F106 HydrophobicContact CD1-CB 4.21Å; L20-F106 HydrophobicContact CD1-CD1 3.87Å; L20-F106 HydrophobicContact CD1-CG 4.18Å; L20-W117 HydrophobicContact CD1-CD2 4.33Å; L20-W117 HydrophobicContact CD1-CH2 4.37Å; L20-W117 HydrophobicContact CD1-CZ2 3.95Å; L20-W117 HydrophobicContact CG-CZ2 4.27Å
21L90.7Very high71.9Confident24 Ų2472.6 Ų72.613%0.12637%0.366CS..EExtended strand (participates in β ladder)trans-97.1132.2167.8-167.171.8000108.7T45 V90 L91 F106 S107 F109L21-T45 HydrophobicContact CD2-CG2 4.29Å; L21-T45 HydrophobicContact CG-CG2 4.14Å; L21-V90 WeakPolarHBondContact CD2-O 3.47Å; L21-L91 HydrophobicContact CB-CD2 4.33Å; L21-L91 HydrophobicContact CD2-CD2 3.87Å; L21-L91 HydrophobicContact CG-CD2 3.99Å; L21-F106 CarbonylContact O-C 3.57Å; L21-F106 WeakPolarHBondContact O-CA 3.21Å; L21-S107 PolarHBondContact N-O 2.9Å; L21-S107 PolarHBondContact O-N 2.84Å; L21-F109 HydrophobicContact CB-CZ 4.4Å
22T90Very high71.9Confident1 Ų168.9 Ų68.91%0.00635%0.35CS..EExtended strand (participates in β ladder)trans-142.7167.6175.8-171.20000110.1L26 T45 V46 V48 Y105 F106T22-L26 HydrophobicContact CG2-CD1 4.26Å; T22-T45 CarbonylContact O-C 3.55Å; T22-T45 WeakPolarHBondContact O-CA 3.37Å; T22-T45 WeakPolarHBondContact O-CB 3.46Å; T22-V46 HydrophobicContact CG2-CG1 3.98Å; T22-V46 PolarHBondContact N-O 3.13Å; T22-V46 PolarHBondContact O-N 2.77Å; T22-V48 HydrophobicContact CG2-CB 4.49Å; T22-V48 HydrophobicContact CG2-CG1 3.83Å; T22-V48 HydrophobicContact CG2-CG2 3.78Å; T22-Y105 WeakPolarHBondContact CB-O 3.46Å; T22-Y105 PolarHBondContact OG1-O 3.01Å; T22-F106 HydrophobicContact CG2-CE1 4.42Å
23Y84.7Confident71.8Confident15 Ų1570 Ų706%0.05935%0.348CS..EExtended strand (participates in β ladder)trans-70143.5175-67.8-61.8000111.7K25 I44 T45 L91 Y105Y23-K25 VanDerWaalsContact C-N 3.26Å; Y23-K25 WeakPolarHBondContact CB-O 3.47Å; Y23-K25 CarbonylContact O-C 3.47Å; Y23-K25 PolarHBondContact O-N 3.05Å; Y23-I44 CarbonylContact C-O 3.5Å; Y23-I44 WeakPolarHBondContact CA-O 3.39Å; Y23-I44 HydrophobicContact CD1-CB 4.49Å; Y23-I44 HydrophobicContact CD1-CG2 3.69Å; Y23-I44 HydrophobicContact CE1-CG2 4.01Å; Y23-T45 HydrophobicContact CD1-CG2 3.94Å; Y23-T45 HydrophobicContact CE1-CG2 4.22Å; Y23-L91 HydrophobicContact CD2-CD1 4.37Å; Y23-L91 HydrophobicContact CE1-CD1 4.49Å; Y23-L91 HydrophobicContact CE2-CD1 3.71Å; Y23-Y105 HydrophobicContact CE2-CD2 4.35Å; Y23-Y105 HydrophobicContact CE2-CG 4.21Å
24K78.4Confident71Confident85 Ų8574.8 Ų74.837%0.3736%0.362SS..SBendtrans-56.7-40.8175-76.7-176.4-169.5163.60111.4S42 D43 I44 T45 V46 R73K24-S42 PolarHBondContact NZ-O 3.32Å; K24-D43 WeakPolarHBondContact CD-O 3.42Å; K24-D43 WeakPolarHBondContact CE-O 3.43Å; K24-D43 PolarHBondContact NZ-O 2.67Å; K24-I44 PolarHBondContact N-O 3.26Å; K24-T45 WeakPolarHBondContact CE-O 3.23Å; K24-V46 HydrophobicContact CG-CB 3.92Å; K24-V46 HydrophobicContact CG-CG1 4.14Å; K24-R73 VanDerWaalsContact O-CZ 3.29Å; K24-R73 PolarHBondContact O-NH1 3.04Å; K24-R73 PolarHBondContact O-NH2 3.17Å
25K74.9Confident69.7Low130 Ų13075.6 Ų75.657%0.56537%0.37SS*.SBendtrans-87115.3162.4-75.6-173.9-179.7179.30108.8Y23 M27 E32Y23-K25 VanDerWaalsContact C-N 3.26Å; Y23-K25 WeakPolarHBondContact CB-O 3.47Å; Y23-K25 CarbonylContact O-C 3.47Å; Y23-K25 PolarHBondContact O-N 3.05Å; K25-M27 PolarHBondContact O-N 2.82Å; K25-E32 IonicContact NZ-OE1 3.45Å; K25-E32 IonicContact NZ-OE2 3.03Å
26L59.9Low68.2Low28 Ų2873 Ų7315%0.14737%0.371CS..SBendtrans-66.6-19.2-178.8-139.386.2000113.4T22 L59 I75 Y104T22-L26 HydrophobicContact CG2-CD1 4.26Å; L26-L59 HydrophobicContact CD1-CD1 3.77Å; L26-L59 HydrophobicContact CD2-CD1 4.19Å; L26-I75 HydrophobicContact CD2-CD1 4.12Å; L26-I75 HydrophobicContact CD2-CG1 4.26Å; L26-Y104 HydrophobicContact CD2-CD1 3.65Å; L26-Y104 HydrophobicContact CD2-CE1 3.91Å; L26-Y104 HydrophobicContact CG-CD1 4.03Å
27M55.4Low66Low87 Ų8777 Ų7743%0.42940%0.398SS..  trans-118127-178.4-67.8-81.5-72.100108.7K25 R102 Y104K25-M27 PolarHBondContact O-N 2.82Å; M27-R102 HydrophobicContact CE-CB 4.13Å; M27-R102 HydrophobicContact CE-CG 3.73Å; M27-R102 HydrophobicContact SD-CB 3.84Å; M27-R102 HydrophobicContact SD-CG 4.05Å; M27-Y104 HydrophobicContact SD-CE1 3.88Å
28Q54.6Low63.9Low46 Ų4680.9 Ų80.922%0.21542%0.42CS..  trans-133.1130.9169-71.7-174.1-600109.1L33Q28-L33 HydrophobicContact CB-CD1 4.34Å
29N50.8Low62Low120 Ų12084.2 Ų84.264%0.64244%0.435SS*.  trans-74.4141.3162.8-73.2-12.8000107.8D31 E32N29-D31 PolarHBondContact O-N 3.18Å; N29-E32 PolarHBondContact O-N 3.43Å
30E49.7Very low60.5Low124 Ų12483.2 Ų83.258%0.57944%0.436SS*.Hα-helixtrans-53.7-24.5-179.7-74.5-175.3177.800113.3K103E30-K103 IonicContact OE1-NZ 3.55Å; E30-K103 PolarHBondContact OE1-NZ 2.83Å
31D49.6Very low59Low130 Ų13086.6 Ų86.670%0.69546%0.458SS*.Hα-helixtrans-70.2-28.8177-68.5-33.6000114.1N29N29-D31 PolarHBondContact O-N 3.18Å
32E48.5Very low57.6Low91 Ų9188.9 Ų88.943%0.42548%0.476SS..Hα-helixtrans-72.5-32.2177.7-71.4-167.1166.700111.5K25 N29 K34 S35K25-E32 IonicContact NZ-OE1 3.45Å; K25-E32 IonicContact NZ-OE2 3.03Å; N29-E32 PolarHBondContact O-N 3.43Å; E32-K34 VanDerWaalsContact C-N 3.29Å; E32-K34 PolarHBondContact O-N 2.94Å; E32-S35 PolarHBondContact O-N 3.38Å; E32-S35 PolarHBondContact O-OG 3.19Å
33L50.7Low56.6Low82 Ų8292.8 Ų92.843%0.42950%0.497SS..Hα-helixtrans-64.1-30.1-178.1-110.4123.5000113.5Q28 S35Q28-L33 HydrophobicContact CB-CD1 4.34Å; L33-S35 VanDerWaalsContact C-N 3.34Å
34K49.7Very low56.3Low186 Ų18693.9 Ų93.981%0.80950%0.503SS*.THydrogen-bonded Turntrans-79.5-15.9-179.6-69.4180-178167.80113.7E32E32-K34 VanDerWaalsContact C-N 3.29Å; E32-K34 PolarHBondContact O-N 2.94Å
35S45Very low56.6Low86 Ų8690.2 Ų90.260%0.60149%0.488SS*.THydrogen-bonded Turntrans-108.7-2.5-172.765.40000114.4E32 L33 V37E32-S35 PolarHBondContact O-N 3.38Å; E32-S35 PolarHBondContact O-OG 3.19Å; L33-S35 VanDerWaalsContact C-N 3.34Å; S35-V37 PolarHBondContact O-N 3.41Å
36A44.7Very low57.2Low64 Ų6484.3 Ų84.353%0.52946%0.463SS..  trans-73.992.2179.400000111.6
37V43.1Very low58.7Low121 Ų12184.5 Ų84.573%0.73347%0.465SS*.  trans-46.8137.4162174.70000110.3S35 L39S35-V37 PolarHBondContact O-N 3.41Å; V37-L39 PolarHBondContact O-N 2.9Å
38I45.7Very low60.4Low173 Ų17380.6 Ų80.689%0.88745%0.446SS*.SBendtrans-21.291.2176-50.3169.4000113
39L51.6Low62.1Low99 Ų9982.4 Ų82.452%0.51845%0.451SS..  trans-109.4143.5166-79.3168.2000107.5V37 D43 I44V37-L39 PolarHBondContact O-N 2.9Å; L39-D43 HydrophobicContact CB-CB 4.09Å; L39-D43 HydrophobicContact CD2-CB 4.07Å; L39-I44 HydrophobicContact CB-CD1 3.85Å; L39-I44 HydrophobicContact CB-CG1 3.78Å; L39-I44 HydrophobicContact CD1-CG1 4.32Å
40S59.6Low64.1Low56 Ų5676.7 Ų76.739%0.39242%0.42SS..  trans-59.5147.5174.4172.50000109.3S42 D43S40-S42 WeakPolarHBondContact CB-OG 3.17Å; S40-S42 PolarHBondContact O-N 3.43Å; S40-S42 VanDerWaalsContact O-N 3.09Å; S40-S42 PolarHBondContact OG-N 2.94Å; S40-S42 PolarHBondContact OG-OG 2.86Å; S40-D43 WeakPolarHBondContact CB-OD2 3.37Å; S40-D43 PolarHBondContact N-OD2 2.91Å; S40-D43 VanDerWaalsContact O-CB 3.32Å; S40-D43 WeakPolarHBondContact O-CB 3.39Å; S40-D43 PolarHBondContact O-N 2.96Å
41P61.1Low66.1Low70 Ų7071.1 Ų71.146%0.45540%0.395SS..Hα-helixtrans-46-42.1172.2-31.236.7000113.2D43 I44 T45 V90P41-D43 PolarHBondContact O-N 2.74Å; P41-I44 PolarHBondContact O-N 3.06Å; P41-I44 VanDerWaalsContact O-N 3.17Å; P41-T45 PolarHBondContact O-N 3.32Å; P41-T45 PolarHBondContact O-OG1 2.97Å; P41-V90 HydrophobicContact CB-CG1 3.97Å
42S62.2Low68Low73 Ų7365 Ų6551%0.5136%0.362SS..Hα-helixtrans-61.4-21176.958.10000115K24 S40K24-S42 PolarHBondContact NZ-O 3.32Å; S40-S42 WeakPolarHBondContact CB-OG 3.17Å; S40-S42 PolarHBondContact O-N 3.43Å; S40-S42 VanDerWaalsContact O-N 3.09Å; S40-S42 PolarHBondContact OG-N 2.94Å; S40-S42 PolarHBondContact OG-OG 2.86Å
43D69.7Low69.8Low82 Ų8262 Ų6244%0.43935%0.35SS..Hα-helixtrans-81.6-29.5-179.8-61.2-26.9000110.9K24 L39 S40 P41K24-D43 WeakPolarHBondContact CD-O 3.42Å; K24-D43 WeakPolarHBondContact CE-O 3.43Å; K24-D43 PolarHBondContact NZ-O 2.67Å; L39-D43 HydrophobicContact CB-CB 4.09Å; L39-D43 HydrophobicContact CD2-CB 4.07Å; S40-D43 WeakPolarHBondContact CB-OD2 3.37Å; S40-D43 PolarHBondContact N-OD2 2.91Å; S40-D43 VanDerWaalsContact O-CB 3.32Å; S40-D43 WeakPolarHBondContact O-CB 3.39Å; S40-D43 PolarHBondContact O-N 2.96Å; P41-D43 PolarHBondContact O-N 2.74Å
44I77.9Confident71.1Confident38 Ų3858.9 Ų58.920%0.19534%0.338CS..Hα-helixtrans-104.1-31.1-171.8-36.8178.1000112.1Y23 K24 L39 P41Y23-I44 CarbonylContact C-O 3.5Å; Y23-I44 WeakPolarHBondContact CA-O 3.39Å; Y23-I44 HydrophobicContact CD1-CB 4.49Å; Y23-I44 HydrophobicContact CD1-CG2 3.69Å; Y23-I44 HydrophobicContact CE1-CG2 4.01Å; K24-I44 PolarHBondContact N-O 3.26Å; L39-I44 HydrophobicContact CB-CD1 3.85Å; L39-I44 HydrophobicContact CB-CG1 3.78Å; L39-I44 HydrophobicContact CD1-CG1 4.32Å; P41-I44 PolarHBondContact O-N 3.06Å; P41-I44 VanDerWaalsContact O-N 3.17Å
45T84.8Confident72.7Confident8 Ų852.1 Ų52.15%0.04931%0.311CS..EExtended strand (participates in β ladder)trans-103.8158.4178.954.20000113.4L21 T22 Y23 K24 P41 V90 L91L21-T45 HydrophobicContact CD2-CG2 4.29Å; L21-T45 HydrophobicContact CG-CG2 4.14Å; T22-T45 CarbonylContact O-C 3.55Å; T22-T45 WeakPolarHBondContact O-CA 3.37Å; T22-T45 WeakPolarHBondContact O-CB 3.46Å; Y23-T45 HydrophobicContact CD1-CG2 3.94Å; Y23-T45 HydrophobicContact CE1-CG2 4.22Å; K24-T45 WeakPolarHBondContact CE-O 3.23Å; P41-T45 PolarHBondContact O-N 3.32Å; P41-T45 PolarHBondContact O-OG1 2.97Å; T45-V90 HydrophobicContact CG2-CG1 3.41Å; T45-V90 VanDerWaalsContact CG2-CG1 3.41Å; T45-L91 HydrophobicContact CG2-CD2 3.82Å
46V87.8Confident74.6Confident6 Ų650 Ų504%0.03629%0.293CS..EExtended strand (participates in β ladder)trans-134.7142.4174.557.20000108.4T22 K24 V48 D61 E63T22-V46 HydrophobicContact CG2-CG1 3.98Å; T22-V46 PolarHBondContact N-O 3.13Å; T22-V46 PolarHBondContact O-N 2.77Å; K24-V46 HydrophobicContact CG-CB 3.92Å; K24-V46 HydrophobicContact CG-CG1 4.14Å; V46-V48 HydrophobicContact CG1-CG1 4.1Å; V46-D61 WeakPolarHBondContact CG2-OD1 3.31Å; V46-E63 HydrophobicContact CG2-CB 4.4Å; V46-E63 HydrophobicContact CG2-CG 4.33Å
47T90.3Very high76.7Confident32 Ų3246.9 Ų46.920%0.19627%0.268CS..EExtended strand (participates in β ladder)trans-83.9121.1171.7-49.40000110M19 V62 E63 F109M19-T47 HydrophobicContact CE-CG2 3.38Å; T47-V62 PolarHBondContact O-N 2.94Å; T47-E63 PolarHBondContact N-OE1 3.4Å; T47-F109 HydrophobicContact CG2-CE2 4.08Å; T47-F109 HydrophobicContact CG2-CZ 3.82Å
48V91.1Very high79Confident5 Ų542.8 Ų42.83%0.0324%0.242CC..EExtended strand (participates in β ladder)trans-115140.8177.8-63.20000110.2M19 L20 T22 V46 L59 Y60M19-V48 WeakPolarHBondContact CA-O 3.35Å; L20-V48 HydrophobicContact CB-CG2 4.1Å; L20-V48 PolarHBondContact N-O 2.96Å; L20-V48 WeakPolarHBondContact O-CG2 3.3Å; L20-V48 PolarHBondContact O-N 3.44Å; L20-V48 VanDerWaalsContact O-O 3.13Å; T22-V48 HydrophobicContact CG2-CB 4.49Å; T22-V48 HydrophobicContact CG2-CG1 3.83Å; T22-V48 HydrophobicContact CG2-CG2 3.78Å; V46-V48 HydrophobicContact CG1-CG1 4.1Å; V48-L59 HydrophobicContact CG2-CD2 3.98Å; V48-Y60 CarbonylContact C-O 3.59Å; V48-Y60 VanDerWaalsContact CA-O 3.25Å; V48-Y60 WeakPolarHBondContact CA-O 3.27Å
49R91.4Very high81.1Confident85 Ų8534.6 Ų34.632%0.32120%0.2SC..EExtended strand (participates in β ladder)trans-81.3119.7160.8-177.8-177.367.5156.4-10.5107.2E17 M19 Y60 V62E17-R49 HydrophobicContact CG-CG 4.38Å; E17-R49 VanDerWaalsContact OE1-CD 3.31Å; E17-R49 WeakPolarHBondContact OE1-CD 3.16Å; E17-R49 IonicContact OE1-CZ 3.67Å; E17-R49 IonicContact OE1-NE 3.91Å; E17-R49 IonicContact OE1-NH1 3.84Å; E17-R49 PolarHBondContact OE1-NH1 3.02Å; M19-R49 HydrophobicContact SD-CB 3.66Å; M19-R49 HydrophobicContact SD-CG 4.17Å; R49-Y60 PolarHBondContact N-O 2.95Å; R49-Y60 WeakPolarHBondContact O-CD2 3.35Å; R49-Y60 PolarHBondContact O-N 3.31Å; R49-V62 HydrophobicContact CB-CG2 3.94Å
50A92.6Very high82.8Confident0 Ų031.3 Ų31.30%018%0.181CC..EExtended strand (participates in β ladder)trans-106.212917900000110.2E17 S18 L20 M57 L58 L59 W117E17-A50 VanDerWaalsContact CA-O 3.25Å; E17-A50 WeakPolarHBondContact CA-O 3.41Å; S18-A50 PolarHBondContact N-O 3.06Å; S18-A50 PolarHBondContact O-N 2.81Å; L20-A50 HydrophobicContact CD1-CB 3.51Å; L20-A50 HydrophobicContact CG-CB 4.01Å; A50-M57 HydrophobicContact CB-CE 4.1Å; A50-L58 CarbonylContact C-O 3.51Å; A50-L58 WeakPolarHBondContact CA-O 3.34Å; A50-L59 HydrophobicContact CB-CD2 3.61Å; A50-W117 HydrophobicContact CB-CH2 3.75Å; A50-W117 HydrophobicContact CB-CZ2 3.98Å
51T90.8Very high84Confident7 Ų730.2 Ų30.24%0.04317%0.171CC..EExtended strand (participates in β ladder)trans-124.8117178.8-47.70000109V14 E17 V53 L58V14-T51 HydrophobicContact CB-CG2 4.35Å; V14-T51 HydrophobicContact CG1-CG2 3.65Å; V14-T51 HydrophobicContact CG2-CG2 3.82Å; E17-T51 HydrophobicContact CB-CG2 4.3Å; E17-T51 HydrophobicContact CG-CG2 4.35Å; T51-V53 HydrophobicContact CG2-CG2 3.81Å; T51-L58 PolarHBondContact N-O 3.23Å; T51-L58 PolarHBondContact O-N 2.96Å
52L90Very high85.1Confident0 Ų029.2 Ų29.20%016%0.163CC..EExtended strand (participates in β ladder)trans-92.4115.9175.9-179.161.8000109.7V14 K15 K16 M57 L77 W117 A120 I121 C124V14-L52 CarbonylContact C-O 3.55Å; V14-L52 WeakPolarHBondContact CA-O 3.37Å; K15-L52 HydrophobicContact CB-CB 4.41Å; K15-L52 HydrophobicContact CB-CD2 4.14Å; K15-L52 HydrophobicContact CB-CG 4.07Å; K15-L52 PolarHBondContact N-O 3.28Å; K16-L52 PolarHBondContact O-N 3.35Å; L52-M57 HydrophobicContact CD1-CB 4.12Å; L52-L77 HydrophobicContact CD1-CD1 3.46Å; L52-L77 VanDerWaalsContact CD1-CD1 3.46Å; L52-W117 HydrophobicContact CB-CZ3 4.07Å; L52-A120 HydrophobicContact CD2-CB 3.92Å; L52-I121 HydrophobicContact CD2-CG1 4.43Å; L52-C124 HydrophobicContact CD1-CB 4.25Å; L52-C124 HydrophobicContact CD2-CB 4.03Å; L52-C124 HydrophobicContact CG-CB 4.37Å
53V85.4Confident85.9Confident29 Ų2930.9 Ų30.918%0.17616%0.163CC..EExtended strand (participates in β ladder)trans-126.8115.1-178.4-1740000108.9A12 V14 T51 N55 V56 L58A12-V53 HydrophobicContact CB-CG1 3.69Å; V14-V53 HydrophobicContact CG2-CG2 4.11Å; T51-V53 HydrophobicContact CG2-CG2 3.81Å; V53-N55 PolarHBondContact O-N 3.35Å; V53-V56 PolarHBondContact N-O 3.38Å; V53-V56 PolarHBondContact O-N 3.21Å; V53-L58 HydrophobicContact CG2-CD1 4.34Å
54G78.6Confident86.2Confident17 Ų1731.1 Ų31.118%0.17517%0.171CC..THydrogen-bonded Turntrans56.4-124.7-172.200000110.8C124G54-C124 VanDerWaalsContact O-CB 3.23Å; G54-C124 WeakPolarHBondContact O-CB 3.44Å
55N82.6Confident86.1Confident44 Ų4431.1 Ų31.124%0.23518%0.177CC..THydrogen-bonded Turntrans-9820.4173.865.5-33.5000113.8V53 L77 C124 L129V53-N55 PolarHBondContact O-N 3.35Å; N55-L77 WeakPolarHBondContact O-CB 3.4Å; N55-L77 PolarHBondContact O-N 3.09Å; N55-C124 WeakPolarHBondContact CA-O 3.27Å; N55-C124 VanDerWaalsContact CB-O 3.25Å; N55-C124 WeakPolarHBondContact CB-O 3.44Å; N55-L129 HydrophobicContact CB-CD1 3.81Å
56V86.2Confident85.6Confident40 Ų4035.8 Ų35.824%0.24221%0.207CC..EExtended strand (participates in β ladder)trans-121125.6-179.6-173.80000110.1V53 L58 A74 I75 L76V53-V56 PolarHBondContact N-O 3.38Å; V53-V56 PolarHBondContact O-N 3.21Å; V56-L58 HydrophobicContact CG1-CD2 3.62Å; V56-L58 HydrophobicContact CG1-CG 4.26Å; V56-A74 HydrophobicContact CG1-CB 4.18Å; V56-I75 WeakPolarHBondContact CA-O 3.25Å; V56-L76 HydrophobicContact CG2-CD1 3.77Å
57M89.1Confident84.9Confident0 Ų040 Ų400%024%0.243CC..EExtended strand (participates in β ladder)trans-98.9111.5171.4-177.7169.414600109.6L20 A50 L52 L59 A74 I75 I97 F106 W117L20-M57 HydrophobicContact CD1-CE 4.08Å; A50-M57 HydrophobicContact CB-CE 4.1Å; L52-M57 HydrophobicContact CD1-CB 4.12Å; M57-L59 HydrophobicContact CE-CD2 3.62Å; M57-L59 HydrophobicContact CG-CD2 4.4Å; M57-A74 CarbonylContact O-C 3.58Å; M57-A74 VanDerWaalsContact O-CA 3.31Å; M57-A74 WeakPolarHBondContact O-CA 3.22Å; M57-I75 HydrophobicContact CB-CB 4.34Å; M57-I75 PolarHBondContact N-O 3.41Å; M57-I75 PolarHBondContact O-N 2.94Å; M57-I97 HydrophobicContact CE-CD1 4.5Å; M57-I97 HydrophobicContact SD-CD1 3.91Å; M57-F106 HydrophobicContact CE-CD1 3.84Å; M57-F106 HydrophobicContact CE-CD2 4.05Å; M57-F106 HydrophobicContact CE-CE1 3.38Å; M57-F106 HydrophobicContact CE-CE2 3.59Å; M57-F106 HydrophobicContact CE-CG 4.16Å; M57-F106 HydrophobicContact CE-CZ 3.25Å; M57-W117 HydrophobicContact SD-CZ3 4.21Å
58L89.8Confident84.2Confident35 Ų3540.2 Ų40.218%0.18325%0.245CC..EExtended strand (participates in β ladder)trans-93.1133.7-180-58.3178.5000109.9A50 T51 V53 V56 Y60 P71 A74A50-L58 CarbonylContact C-O 3.51Å; A50-L58 WeakPolarHBondContact CA-O 3.34Å; T51-L58 PolarHBondContact N-O 3.23Å; T51-L58 PolarHBondContact O-N 2.96Å; V53-L58 HydrophobicContact CG2-CD1 4.34Å; V56-L58 HydrophobicContact CG1-CD2 3.62Å; V56-L58 HydrophobicContact CG1-CG 4.26Å; L58-Y60 HydrophobicContact CB-CE2 3.95Å; L58-P71 HydrophobicContact CB-CB 4.07Å; L58-P71 HydrophobicContact CD2-CB 4.25Å; L58-P71 HydrophobicContact CD2-CG 4.1Å; L58-A74 HydrophobicContact CD2-CB 3.84Å
59L90.1Very high83.4Confident1 Ų145.3 Ų45.31%0.00528%0.276CS..EExtended strand (participates in β ladder)trans-118.6126.3-179.8-59.6178.6000109.8L26 V48 A50 M57 P71 S72 R73 F106L26-L59 HydrophobicContact CD1-CD1 3.77Å; L26-L59 HydrophobicContact CD2-CD1 4.19Å; V48-L59 HydrophobicContact CG2-CD2 3.98Å; A50-L59 HydrophobicContact CB-CD2 3.61Å; M57-L59 HydrophobicContact CE-CD2 3.62Å; M57-L59 HydrophobicContact CG-CD2 4.4Å; L59-P71 CarbonylContact O-C 3.5Å; L59-S72 PolarHBondContact O-N 3.26Å; L59-R73 HydrophobicContact CB-CB 4.17Å; L59-R73 HydrophobicContact CD1-CB 4.27Å; L59-R73 PolarHBondContact N-O 3.16Å; L59-R73 PolarHBondContact O-N 2.77Å; L59-R73 VanDerWaalsContact O-N 3.13Å; L59-F106 HydrophobicContact CD1-CE1 3.92Å; L59-F106 HydrophobicContact CD1-CZ 4.05Å; L59-F106 HydrophobicContact CD2-CE1 3.95Å; L59-F106 HydrophobicContact CD2-CZ 4.47Å
60Y88.7Confident82.7Confident29 Ų2948.8 Ų48.811%0.11429%0.294CS..EExtended strand (participates in β ladder)trans-111.9119175.3-54.5-101.1000108.4V48 R49 L58 V62 F70 P71V48-Y60 CarbonylContact C-O 3.59Å; V48-Y60 VanDerWaalsContact CA-O 3.25Å; V48-Y60 WeakPolarHBondContact CA-O 3.27Å; R49-Y60 PolarHBondContact N-O 2.95Å; R49-Y60 WeakPolarHBondContact O-CD2 3.35Å; R49-Y60 PolarHBondContact O-N 3.31Å; L58-Y60 HydrophobicContact CB-CE2 3.95Å; Y60-V62 PolarHBondContact O-N 3.42Å; Y60-F70 WeakPolarHBondContact CD1-O 3.44Å; Y60-P71 HydrophobicContact CD1-CB 4.39Å; Y60-P71 HydrophobicContact CE1-CB 4Å; Y60-P71 HydrophobicContact CE2-CB 4.41Å
61D84.5Confident82.1Confident34 Ų3451.3 Ų51.318%0.18231%0.311CS..EExtended strand (participates in β ladder)trans-71.2112.9173.5-176.9-13.6000109.8V46 E63 S64 A65 S72V46-D61 WeakPolarHBondContact CG2-OD1 3.31Å; D61-E63 PolarHBondContact OD1-N 3.46Å; D61-S64 WeakPolarHBondContact CB-OG 3.35Å; D61-S64 PolarHBondContact OD1-N 3.41Å; D61-S64 WeakPolarHBondContact OD2-CB 3.43Å; D61-S64 PolarHBondContact OD2-OG 2.97Å; D61-A65 CarbonylContact O-C 3.49Å; D61-A65 PolarHBondContact O-N 3.48Å; D61-S72 WeakPolarHBondContact CB-OG 3.34Å; D61-S72 PolarHBondContact N-OG 2.69Å
62V83.6Confident81.6Confident48 Ų4853.9 Ų53.929%0.29133%0.329SS..THydrogen-bonded Turntrans-81.4-22.2-177-178.80000111.5M19 T47 R49 Y60 P66M19-V62 HydrophobicContact CE-CB 3.98Å; M19-V62 HydrophobicContact CE-CG1 4.04Å; M19-V62 HydrophobicContact CE-CG2 3.51Å; M19-V62 HydrophobicContact SD-CG2 4.06Å; T47-V62 PolarHBondContact O-N 2.94Å; R49-V62 HydrophobicContact CB-CG2 3.94Å; Y60-V62 PolarHBondContact O-N 3.42Å; V62-P66 HydrophobicContact CG1-CB 4.43Å; V62-P66 WeakPolarHBondContact O-CB 3.33Å; V62-P66 WeakPolarHBondContact O-CD 3.49Å
63E80Confident81.2Confident109 Ų10958.5 Ų58.551%0.50935%0.346SS..THydrogen-bonded Turntrans-81.4-42.3-178.5-67.8172.6-154.600111.3V46 T47 D61V46-E63 HydrophobicContact CG2-CB 4.4Å; V46-E63 HydrophobicContact CG2-CG 4.33Å; T47-E63 PolarHBondContact N-OE1 3.4Å; D61-E63 PolarHBondContact OD1-N 3.46Å
64S75.6Confident81.2Confident86 Ų8660.1 Ų60.160%0.60136%0.363SS*.THydrogen-bonded Turntrans-84.9-31.7-179.864.70000114.1D61D61-S64 WeakPolarHBondContact CB-OG 3.35Å; D61-S64 PolarHBondContact OD1-N 3.41Å; D61-S64 WeakPolarHBondContact OD2-CB 3.43Å; D61-S64 PolarHBondContact OD2-OG 2.97Å
65A75.8Confident81.6Confident39 Ų3959.5 Ų59.532%0.32236%0.356SS..  trans-149.369.1-175.800000113D61 A67 S68D61-A65 CarbonylContact O-C 3.49Å; D61-A65 PolarHBondContact O-N 3.48Å; A65-A67 PolarHBondContact O-N 3Å; A65-S68 WeakPolarHBondContact O-CB 3.19Å; A65-S68 PolarHBondContact O-N 3.22Å
66P73.4Confident81.6Confident106 Ų10661.1 Ų61.169%0.68836%0.364SS*.THydrogen-bonded Turntrans-59.4-23.7-172.118.7-30.3000115.1V62V62-P66 HydrophobicContact CG1-CB 4.43Å; V62-P66 WeakPolarHBondContact O-CB 3.33Å; V62-P66 WeakPolarHBondContact O-CD 3.49Å
67A73.9Confident81.6Confident95 Ų9559.2 Ų59.279%0.78535%0.352SS*.THydrogen-bonded Turntrans-103.78.3178.900000113.8A65 T69A65-A67 PolarHBondContact O-N 3Å; A67-T69 PolarHBondContact O-N 3.05Å
68S75.5Confident80.9Confident35 Ų3562.6 Ų62.625%0.24537%0.368CS..  trans-67.9125.4-179.3-176.40000111.5A65 F70A65-S68 WeakPolarHBondContact O-CB 3.19Å; A65-S68 PolarHBondContact O-N 3.22Å; S68-F70 VanDerWaalsContact C-N 3.27Å; S68-F70 PolarHBondContact OG-N 3.27Å; S68-F70 PolarHBondContact OG-O 2.92Å
69T74.4Confident80.2Confident112 Ų11269 Ų6969%0.68739%0.39SS*.SBendtrans-81-10.4167.152.30000112.5A67A67-T69 PolarHBondContact O-N 3.05Å
70F76.1Confident79.6Confident158 Ų15869.6 Ų69.669%0.69339%0.394SS*.SBendtrans-97.5131.1178.6-63.2-79.4000110.8Y60 S68Y60-F70 WeakPolarHBondContact CD1-O 3.44Å; S68-F70 VanDerWaalsContact C-N 3.27Å; S68-F70 PolarHBondContact OG-N 3.27Å; S68-F70 PolarHBondContact OG-O 2.92Å
71P80.5Confident79.2Confident53 Ų5371.9 Ų71.934%0.34441%0.411SS..  trans-67.4135.1177.128.7-33.7000110.1L58 L59 Y60 R73L58-P71 HydrophobicContact CB-CB 4.07Å; L58-P71 HydrophobicContact CD2-CB 4.25Å; L58-P71 HydrophobicContact CD2-CG 4.1Å; L59-P71 CarbonylContact O-C 3.5Å; Y60-P71 HydrophobicContact CD1-CB 4.39Å; Y60-P71 HydrophobicContact CE1-CB 4Å; Y60-P71 HydrophobicContact CE2-CB 4.41Å; P71-R73 VanDerWaalsContact C-N 3.32Å
72S79.6Confident79.3Confident61 Ų6170.6 Ų70.643%0.42741%0.405SS..SBendtrans-69.5-33.3174.6-45.90000111.3L59 D61L59-S72 PolarHBondContact O-N 3.26Å; D61-S72 WeakPolarHBondContact CB-OG 3.34Å; D61-S72 PolarHBondContact N-OG 2.69Å
73R83Confident79.3Confident97 Ų9773.4 Ų73.437%0.36642%0.415SS..EExtended strand (participates in β ladder)trans-148.5158.6-178.8-56.4173.7-176.4167.40.1110.6K24 L59 P71K24-R73 VanDerWaalsContact O-CZ 3.29Å; K24-R73 PolarHBondContact O-NH1 3.04Å; K24-R73 PolarHBondContact O-NH2 3.17Å; L59-R73 HydrophobicContact CB-CB 4.17Å; L59-R73 HydrophobicContact CD1-CB 4.27Å; L59-R73 PolarHBondContact N-O 3.16Å; L59-R73 PolarHBondContact O-N 2.77Å; L59-R73 VanDerWaalsContact O-N 3.13Å; P71-R73 VanDerWaalsContact C-N 3.32Å
74A84.6Confident79.7Confident64 Ų6472 Ų7253%0.52941%0.41SS..EExtended strand (participates in β ladder)trans-139.714317400000110.9V56 M57 L58V56-A74 HydrophobicContact CG1-CB 4.18Å; M57-A74 CarbonylContact O-C 3.58Å; M57-A74 VanDerWaalsContact O-CA 3.31Å; M57-A74 WeakPolarHBondContact O-CA 3.22Å; L58-A74 HydrophobicContact CD2-CB 3.84Å
75I85.9Confident80.1Confident4 Ų470.9 Ų70.92%0.02140%0.396CS..EExtended strand (participates in β ladder)trans-117.8124.3173-56.7173.7000107.9L26 V56 M57 L77 Y104 F106L26-I75 HydrophobicContact CD2-CD1 4.12Å; L26-I75 HydrophobicContact CD2-CG1 4.26Å; V56-I75 WeakPolarHBondContact CA-O 3.25Å; M57-I75 HydrophobicContact CB-CB 4.34Å; M57-I75 PolarHBondContact N-O 3.41Å; M57-I75 PolarHBondContact O-N 2.94Å; I75-L77 HydrophobicContact CG2-CD2 4.04Å; I75-Y104 HydrophobicContact CD1-CD1 4.03Å; I75-Y104 HydrophobicContact CD1-CD2 4.18Å; I75-Y104 HydrophobicContact CD1-CE1 4.49Å; I75-Y104 HydrophobicContact CD1-CG 3.84Å; I75-Y104 HydrophobicContact CG2-CD2 4.44Å; I75-Y104 HydrophobicContact CG2-CE2 4.21Å; I75-F106 HydrophobicContact CD1-CE2 3.95Å; I75-F106 HydrophobicContact CD1-CZ 3.65Å
76L84.1Confident80.5Confident77 Ų7775.2 Ų75.240%0.40341%0.413SS..EExtended strand (participates in β ladder)trans-91.7116.5175.6-17670.1000109.7V56 E78 Q99V56-L76 HydrophobicContact CG2-CD1 3.77Å; L76-E78 HydrophobicContact CD2-CG 3.87Å; L76-E78 WeakPolarHBondContact CD2-OE1 3.31Å; L76-E78 HydrophobicContact CG-CG 3.97Å; L76-E78 PolarHBondContact O-N 3.49Å; L76-E78 VanDerWaalsContact O-N 3.13Å; L76-Q99 VanDerWaalsContact O-CD 3.24Å; L76-Q99 PolarHBondContact O-NE2 2.78Å; L76-Q99 PolarHBondContact O-OE1 3.07Å
77L84.7Confident80.9Confident0 Ų074.2 Ų74.20%041%0.407CS..  trans-87.475.7-173.8-57.9175000111.6L52 N55 I75 C80 I97 I121 C124 S125 Y126L52-L77 HydrophobicContact CD1-CD1 3.46Å; L52-L77 VanDerWaalsContact CD1-CD1 3.46Å; N55-L77 WeakPolarHBondContact O-CB 3.4Å; N55-L77 PolarHBondContact O-N 3.09Å; I75-L77 HydrophobicContact CG2-CD2 4.04Å; L77-C80 HydrophobicContact CD2-CB 4.24Å; L77-I97 HydrophobicContact CD2-CD1 4.45Å; L77-I97 HydrophobicContact CD2-CG2 4.18Å; L77-I121 HydrophobicContact CD1-CG2 4Å; L77-I121 HydrophobicContact CD2-CG2 4.07Å; L77-C124 HydrophobicContact CD1-CB 4.41Å; L77-S125 WeakPolarHBondContact O-CA 3.31Å; L77-Y126 PolarHBondContact O-N 2.85Å
78E74.6Confident81Confident71 Ų7172.9 Ų72.933%0.33239%0.386SS..SBendtrans-84.8-82.1176.4-67.2-177.7161.500111.8L76 Y100L76-E78 HydrophobicContact CD2-CG 3.87Å; L76-E78 WeakPolarHBondContact CD2-OE1 3.31Å; L76-E78 HydrophobicContact CG-CG 3.97Å; L76-E78 PolarHBondContact O-N 3.49Å; L76-E78 VanDerWaalsContact O-N 3.13Å; E78-Y100 PolarHBondContact OE2-OH 3.31Å
79R75.8Confident80.9Confident171 Ų17176.5 Ų76.565%0.64542%0.418SS*.SBendtrans-107.371.3176.2-66.4-173.9-179.8174.32.8109.4Y100R79-Y100 HydrophobicContact CB-CE1 4.43Å
80C77.5Confident81.1Confident12 Ų1272.7 Ų72.78%0.08139%0.394CS..EExtended strand (participates in β ladder)trans-107139.6-177.464.60000112L77 I97 T98 Q99L77-C80 HydrophobicContact CD2-CB 4.24Å; C80-I97 HydrophobicContact CB-CG2 3.87Å; C80-T98 CarbonylContact C-O 3.51Å; C80-T98 VanDerWaalsContact CA-O 3.27Å; C80-T98 WeakPolarHBondContact CA-O 3.27Å; C80-Q99 HydrophobicContact CB-CB 4.49Å
81V79.7Confident81.5Confident78 Ų7865.1 Ų65.147%0.47336%0.361SS..EExtended strand (participates in β ladder)trans-109.2122167.6-177.50000107.7Q83 I97 T98V81-Q83 HydrophobicContact CG1-CG 3.96Å; V81-I97 CarbonylContact O-C 3.5Å; V81-I97 WeakPolarHBondContact O-CA 3.29Å; V81-T98 PolarHBondContact N-O 3.43Å; V81-T98 PolarHBondContact O-N 3.43Å
82A86.4Confident81.6Confident7 Ų765.3 Ų65.36%0.05836%0.363CS..EExtended strand (participates in β ladder)trans-107126.2175.200000109.8V96 V118 I121 I122A82-V96 WeakPolarHBondContact CA-O 3.47Å; A82-V118 HydrophobicContact CB-CB 4.49Å; A82-V118 HydrophobicContact CB-CG1 4.1Å; A82-V118 HydrophobicContact CB-CG2 4.38Å; A82-V118 WeakPolarHBondContact O-CG1 3.43Å; A82-I121 HydrophobicContact CB-CB 4.17Å; A82-I121 HydrophobicContact CB-CG2 3.79Å; A82-I122 HydrophobicContact CB-CG1 4.19Å
83Q85Confident82.2Confident107 Ų10766.2 Ų66.250%0.536%0.357SS..EExtended strand (participates in β ladder)trans-136.1151.2-177.1-71.3174.9-5.500110.9V81 F95 V96V81-Q83 HydrophobicContact CG1-CG 3.96Å; Q83-F95 CarbonylContact O-C 3.48Å; Q83-F95 VanDerWaalsContact O-CA 3.22Å; Q83-F95 WeakPolarHBondContact O-CA 3.46Å; Q83-F95 WeakPolarHBondContact O-CB 3.47Å; Q83-V96 HydrophobicContact CB-CG1 4.22Å; Q83-V96 PolarHBondContact N-O 3.21Å; Q83-V96 PolarHBondContact O-N 2.82Å
84L88.2Confident82.5Confident78 Ų7861.6 Ų61.641%0.40834%0.34SS..EExtended strand (participates in β ladder)trans-76.1140.4169-60-177.4000109F95 R114 V118L84-F95 HydrophobicContact CD2-CB 4.2Å; L84-R114 HydrophobicContact CD1-CG 4.34Å; L84-R114 HydrophobicContact CD2-CB 3.83Å; L84-R114 HydrophobicContact CD2-CG 3.52Å; L84-V118 HydrophobicContact CD2-CG2 3.65Å; L84-V118 HydrophobicContact CG-CG2 4.36Å
85E84.2Confident82.9Confident64 Ų6458.6 Ų58.630%0.29932%0.315SS..  trans-114.4156.9174.6-82.8-76.7-171.300109.7P94 V96 Y105E85-P94 HydrophobicContact CB-CB 4.06Å; E85-P94 HydrophobicContact CB-CG 3.81Å; E85-P94 PolarHBondContact N-O 2.82Å; E85-P94 VanDerWaalsContact N-O 3.11Å; E85-V96 HydrophobicContact CG-CB 4.06Å; E85-V96 HydrophobicContact CG-CG1 3.76Å; E85-Y105 HydrophobicContact CG-CE1 4.34Å
86D82.8Confident83.1Confident129 Ų12958.5 Ų58.569%0.6932%0.315SS*.PPolyproline II helixtrans-67.6147.1173.4-74.3-33.7000110.5L88 P94D86-L88 PolarHBondContact O-N 3.37Å; D86-P94 WeakPolarHBondContact O-CG 3.3Å
87P81.6Confident83.4Confident86 Ų8654.9 Ų54.956%0.55830%0.295SS*.PPolyproline II helixtrans-50124.5177.4-29.336.5000112.8P92P87-P92 VanDerWaalsContact CB-O 3.27Å; P87-P92 WeakPolarHBondContact CB-O 3.38Å; P87-P92 WeakPolarHBondContact CG-O 3.48Å
88L76.1Confident83.3Confident67 Ų6756.7 Ų56.735%0.35131%0.306SS..PPolyproline II helixtrans-98.9155.7173.8-61.7168.8000109.4D86 V90 L91D86-L88 PolarHBondContact O-N 3.37Å; L88-V90 PolarHBondContact O-N 3.33Å; L88-L91 HydrophobicContact CB-CB 4.18Å; L88-L91 HydrophobicContact CD1-CB 4.49Å; L88-L91 HydrophobicContact CD1-CD1 4.3Å; L88-L91 PolarHBondContact N-O 3.36Å; L88-L91 CarbonylContact O-C 3.53Å; L88-L91 PolarHBondContact O-N 2.94Å; L88-L91 VanDerWaalsContact O-O 3.09Å
89A74.1Confident83.6Confident111 Ų11154 Ų5492%0.91729%0.294SS*.SBendtrans-53.8-27.8-178.700000114.2
90V78.6Confident83.7Confident31 Ų3152 Ų5219%0.18829%0.287CS..SBendtrans-107.6-17.7-177.7-167.20000112.3L21 P41 T45 L88L21-V90 WeakPolarHBondContact CD2-O 3.47Å; P41-V90 HydrophobicContact CB-CG1 3.97Å; T45-V90 HydrophobicContact CG2-CG1 3.41Å; T45-V90 VanDerWaalsContact CG2-CG1 3.41Å; L88-V90 PolarHBondContact O-N 3.33Å
91L83.6Confident83.5Confident0 Ų059.1 Ų59.10%033%0.325CS..  trans-128.894.4-175.3-65.7-179.2000108.8L21 Y23 T45 L88 Y93 P94L21-L91 HydrophobicContact CB-CD2 4.33Å; L21-L91 HydrophobicContact CD2-CD2 3.87Å; L21-L91 HydrophobicContact CG-CD2 3.99Å; Y23-L91 HydrophobicContact CD2-CD1 4.37Å; Y23-L91 HydrophobicContact CE1-CD1 4.49Å; Y23-L91 HydrophobicContact CE2-CD1 3.71Å; T45-L91 HydrophobicContact CG2-CD2 3.82Å; L88-L91 HydrophobicContact CB-CB 4.18Å; L88-L91 HydrophobicContact CD1-CB 4.49Å; L88-L91 HydrophobicContact CD1-CD1 4.3Å; L88-L91 PolarHBondContact N-O 3.36Å; L88-L91 CarbonylContact O-C 3.53Å; L88-L91 PolarHBondContact O-N 2.94Å; L88-L91 VanDerWaalsContact O-O 3.09Å; L91-Y93 PolarHBondContact O-N 2.91Å; L91-P94 HydrophobicContact CB-CB 4.12Å; L91-P94 WeakPolarHBondContact O-CD 3.3Å
92P83.1Confident83.5Confident57 Ų5761.8 Ų61.837%0.3733%0.326SS..SBendtrans-68.9-33.1-16824.5-34.4000114.7P87 S107P87-P92 VanDerWaalsContact CB-O 3.27Å; P87-P92 WeakPolarHBondContact CB-O 3.38Å; P87-P92 WeakPolarHBondContact CG-O 3.48Å; P92-S107 WeakPolarHBondContact CD-OG 3.39Å
93Y91.6Very high83.4Confident80 Ų8064.9 Ų64.931%0.31434%0.338SS..EExtended strand (participates in β ladder)trans-13369.8-179.3-55.3-64.6000110.6L91 S107 C108 F109 E111L91-Y93 PolarHBondContact O-N 2.91Å; Y93-S107 PolarHBondContact N-OG 3.06Å; Y93-S107 WeakPolarHBondContact O-CA 3.45Å; Y93-S107 PolarHBondContact O-OG 3.37Å; Y93-C108 PolarHBondContact O-N 3Å; Y93-C108 VanDerWaalsContact O-N 3.08Å; Y93-F109 WeakPolarHBondContact CE2-O 3.5Å; Y93-E111 HydrophobicContact CD1-CB 3.76Å; Y93-E111 HydrophobicContact CD1-CG 3.97Å; Y93-E111 HydrophobicContact CE1-CB 3.75Å; Y93-E111 HydrophobicContact CE1-CG 4.19Å; Y93-E111 HydrophobicContact CG-CB 4.34Å
94P91.1Very high83.6Confident0 Ų060.7 Ų60.70%032%0.318CS..EExtended strand (participates in β ladder)trans-82.5152.2-167.330.1-28.3000113.4E85 D86 L91 F106E85-P94 HydrophobicContact CB-CB 4.06Å; E85-P94 HydrophobicContact CB-CG 3.81Å; E85-P94 PolarHBondContact N-O 2.82Å; E85-P94 VanDerWaalsContact N-O 3.11Å; D86-P94 WeakPolarHBondContact O-CG 3.3Å; L91-P94 HydrophobicContact CB-CB 4.12Å; L91-P94 WeakPolarHBondContact O-CD 3.3Å; P94-F106 CarbonylContact C-O 3.6Å; P94-F106 WeakPolarHBondContact CA-O 3.39Å
95F92.5Very high83.6Confident0 Ų058.5 Ų58.50%031%0.305CS..EExtended strand (participates in β ladder)trans-135.9150.4160.567.7-91.7000108.8L20 Q83 L84 I97 F106 W117 V118 I121L20-F95 HydrophobicContact CD1-CE1 4.28Å; L20-F95 HydrophobicContact CD1-CZ 3.85Å; L20-F95 HydrophobicContact CD2-CE1 4.04Å; L20-F95 HydrophobicContact CD2-CZ 4.43Å; Q83-F95 CarbonylContact O-C 3.48Å; Q83-F95 VanDerWaalsContact O-CA 3.22Å; Q83-F95 WeakPolarHBondContact O-CA 3.46Å; Q83-F95 WeakPolarHBondContact O-CB 3.47Å; L84-F95 HydrophobicContact CD2-CB 4.2Å; F95-I97 HydrophobicContact CD2-CG1 4.37Å; F95-I97 HydrophobicContact CE2-CD1 4.33Å; F95-I97 HydrophobicContact CE2-CG1 4.22Å; F95-F106 HydrophobicContact CD1-CB 4.05Å; F95-F106 HydrophobicContact CD2-CB 4.15Å; F95-F106 HydrophobicContact CD2-CD2 4.39Å; F95-F106 HydrophobicContact CE1-CB 3.53Å; F95-F106 HydrophobicContact CE2-CB 3.64Å; F95-F106 AromaticContact CE2-CD2 3.72Å; F95-F106 HydrophobicContact CE2-CD2 3.72Å; F95-F106 AromaticContact CE2-CG 3.95Å; F95-F106 HydrophobicContact CE2-CG 3.95Å; F95-F106 HydrophobicContact CG-CB 4.35Å; F95-F106 HydrophobicContact CZ-CB 3.32Å; F95-F106 HydrophobicContact CZ-CD2 4.11Å; F95-F106 AromaticContact CZ-CG 3.85Å; F95-F106 HydrophobicContact CZ-CG 3.85Å; F95-F106 PolarHBondContact N-O 2.97Å; F95-F106 PolarHBondContact O-N 3.37Å; F95-F106 VanDerWaalsContact O-O 3.05Å; F95-W117 HydrophobicContact CD1-CB 4.31Å; F95-W117 HydrophobicContact CE1-CB 3.77Å; F95-W117 AromaticContact CE1-CG 3.94Å; F95-W117 HydrophobicContact CE1-CG 3.94Å; F95-W117 HydrophobicContact CE2-CB 4.34Å; F95-W117 HydrophobicContact CZ-CB 3.77Å; F95-W117 HydrophobicContact CZ-CD2 4.19Å; F95-W117 HydrophobicContact CZ-CE3 4.47Å; F95-W117 AromaticContact CZ-CG 3.9Å; F95-W117 HydrophobicContact CZ-CG 3.9Å; F95-V118 HydrophobicContact CB-CG2 3.88Å; F95-V118 HydrophobicContact CG-CG2 4.34Å; F95-I121 HydrophobicContact CD2-CD1 4.24Å; F95-I121 HydrophobicContact CE2-CD1 3.57Å; F95-I121 HydrophobicContact CZ-CD1 4.31Å
96V89.6Confident84.1Confident3 Ų355.4 Ų55.42%0.01829%0.29CS..EExtended strand (participates in β ladder)trans-117.7136.9-178.666.30000110.3A82 Q83 E85 K103 Y104 Y105A82-V96 WeakPolarHBondContact CA-O 3.47Å; Q83-V96 HydrophobicContact CB-CG1 4.22Å; Q83-V96 PolarHBondContact N-O 3.21Å; Q83-V96 PolarHBondContact O-N 2.82Å; E85-V96 HydrophobicContact CG-CB 4.06Å; E85-V96 HydrophobicContact CG-CG1 3.76Å; V96-K103 HydrophobicContact CG2-CB 3.86Å; V96-K103 HydrophobicContact CG2-CD 4.48Å; V96-K103 HydrophobicContact CG2-CG 4.22Å; V96-Y104 WeakPolarHBondContact CA-O 3.46Å; V96-Y105 HydrophobicContact CB-CD1 4.14Å; V96-Y105 HydrophobicContact CB-CE1 4.07Å; V96-Y105 HydrophobicContact CG2-CD1 4.12Å; V96-Y105 HydrophobicContact CG2-CD2 4.49Å; V96-Y105 HydrophobicContact CG2-CE1 3.92Å; V96-Y105 HydrophobicContact CG2-CE2 4.3Å; V96-Y105 HydrophobicContact CG2-CG 4.4Å
97I89.9Confident84.5Confident0 Ų049.3 Ų49.30%026%0.257CS..EExtended strand (participates in β ladder)trans-105.5118.8168.6-51.4177.9000107.4M57 L77 C80 V81 F95 K103 Y104 F106 I121M57-I97 HydrophobicContact CE-CD1 4.5Å; M57-I97 HydrophobicContact SD-CD1 3.91Å; L77-I97 HydrophobicContact CD2-CD1 4.45Å; L77-I97 HydrophobicContact CD2-CG2 4.18Å; C80-I97 HydrophobicContact CB-CG2 3.87Å; V81-I97 CarbonylContact O-C 3.5Å; V81-I97 WeakPolarHBondContact O-CA 3.29Å; F95-I97 HydrophobicContact CD2-CG1 4.37Å; F95-I97 HydrophobicContact CE2-CD1 4.33Å; F95-I97 HydrophobicContact CE2-CG1 4.22Å; I97-K103 CarbonylContact O-C 3.55Å; I97-K103 WeakPolarHBondContact O-CA 3.39Å; I97-Y104 HydrophobicContact CB-CD2 4.3Å; I97-Y104 HydrophobicContact CG2-CD2 4.48Å; I97-Y104 PolarHBondContact N-O 3.08Å; I97-Y104 WeakPolarHBondContact O-CD2 3.43Å; I97-Y104 PolarHBondContact O-N 3.3Å; I97-F106 HydrophobicContact CD1-CD2 4.07Å; I97-F106 HydrophobicContact CD1-CE2 3.75Å; I97-F106 HydrophobicContact CG1-CD2 4.27Å; I97-F106 HydrophobicContact CG1-CE2 4.25Å; I97-I121 HydrophobicContact CD1-CD1 3.58Å; I97-I121 HydrophobicContact CD1-CG1 4.35Å; I97-I121 HydrophobicContact CD1-CG2 4.42Å; I97-I121 HydrophobicContact CG1-CD1 4Å
98T83.9Confident85Confident38 Ų3845.3 Ų45.323%0.23323%0.231CC..EExtended strand (participates in β ladder)trans-105.6125.3176.5-53.40000110C80 V81 R102 K103C80-T98 CarbonylContact C-O 3.51Å; C80-T98 VanDerWaalsContact CA-O 3.27Å; C80-T98 WeakPolarHBondContact CA-O 3.27Å; V81-T98 PolarHBondContact N-O 3.43Å; V81-T98 PolarHBondContact O-N 3.43Å; T98-R102 CarbonylContact C-O 3.52Å; T98-R102 VanDerWaalsContact CA-O 3.26Å; T98-R102 WeakPolarHBondContact CA-O 3.27Å; T98-K103 HydrophobicContact CG2-CG 4.38Å
99Q79.7Confident85.6Confident15 Ų1547.7 Ų47.77%0.0724%0.239CC..EExtended strand (participates in β ladder)trans-145.9122.7178.8-178.5-176.312.600110.5L76 C80 D101 R102 Y104L76-Q99 VanDerWaalsContact O-CD 3.24Å; L76-Q99 PolarHBondContact O-NE2 2.78Å; L76-Q99 PolarHBondContact O-OE1 3.07Å; C80-Q99 HydrophobicContact CB-CB 4.49Å; Q99-D101 VanDerWaalsContact C-N 3.28Å; Q99-D101 PolarHBondContact O-N 2.96Å; Q99-R102 PolarHBondContact N-O 2.84Å; Q99-R102 WeakPolarHBondContact O-CA 3.26Å; Q99-R102 WeakPolarHBondContact O-CB 3.47Å; Q99-R102 WeakPolarHBondContact O-CG 3.47Å; Q99-R102 PolarHBondContact O-N 3.06Å; Q99-Y104 HydrophobicContact CB-CE2 4.45Å
100Y77.7Confident86.2Confident128 Ų12843.8 Ų43.850%0.50221%0.207SC..THydrogen-bonded Turntrans46.950.8-178.6-52.8-62.1000112.2E78 R79 R102E78-Y100 PolarHBondContact OE2-OH 3.31Å; R79-Y100 HydrophobicContact CB-CE1 4.43Å; Y100-R102 PolarHBondContact O-N 2.85Å; Y100-R102 VanDerWaalsContact O-N 3.09Å
101D73.9Confident86.4Confident162 Ų16247.3 Ų47.387%0.86622%0.222SC*.THydrogen-bonded Turntrans63.46.4-175.8-53.2-37.7000116.3Q99Q99-D101 VanDerWaalsContact C-N 3.28Å; Q99-D101 PolarHBondContact O-N 2.96Å
102R79.2Confident86.2Confident135 Ų13554.8 Ų54.851%0.50926%0.257SS..EExtended strand (participates in β ladder)trans-92.9126.2173.8-51.5-174.1175.3-1790.9110.4M27 T98 Q99 Y100 Y104M27-R102 HydrophobicContact CE-CB 4.13Å; M27-R102 HydrophobicContact CE-CG 3.73Å; M27-R102 HydrophobicContact SD-CB 3.84Å; M27-R102 HydrophobicContact SD-CG 4.05Å; T98-R102 CarbonylContact C-O 3.52Å; T98-R102 VanDerWaalsContact CA-O 3.26Å; T98-R102 WeakPolarHBondContact CA-O 3.27Å; Q99-R102 PolarHBondContact N-O 2.84Å; Q99-R102 WeakPolarHBondContact O-CA 3.26Å; Q99-R102 WeakPolarHBondContact O-CB 3.47Å; Q99-R102 WeakPolarHBondContact O-CG 3.47Å; Q99-R102 PolarHBondContact O-N 3.06Å; Y100-R102 PolarHBondContact O-N 2.85Å; Y100-R102 VanDerWaalsContact O-N 3.09Å; R102-Y104 HydrophobicContact CB-CE2 4.07Å; R102-Y104 WeakPolarHBondContact CD-OH 3.49Å
103K84.8Confident86.4Confident71 Ų7154.7 Ų54.731%0.30925%0.253SS..EExtended strand (participates in β ladder)trans-103.6123.4175.3-65.5-177-175.9176.30110.5E30 V96 I97 T98 Y105E30-K103 IonicContact OE1-NZ 3.55Å; E30-K103 PolarHBondContact OE1-NZ 2.83Å; V96-K103 HydrophobicContact CG2-CB 3.86Å; V96-K103 HydrophobicContact CG2-CD 4.48Å; V96-K103 HydrophobicContact CG2-CG 4.22Å; I97-K103 CarbonylContact O-C 3.55Å; I97-K103 WeakPolarHBondContact O-CA 3.39Å; T98-K103 HydrophobicContact CG2-CG 4.38Å; K103-Y105 HydrophobicContact CB-CD2 4.42Å; K103-Y105 HydrophobicContact CB-CE2 3.79Å; K103-Y105 HydrophobicContact CD-CE2 4.31Å; K103-Y105 WeakPolarHBondContact CD-OH 3.26Å
104Y88.7Confident86.1Confident20 Ų2053.1 Ų53.18%0.07825%0.246CC..EExtended strand (participates in β ladder)trans-109.6113.8173.4-51.9-80.1000109.1L26 M27 I75 V96 I97 Q99 R102L26-Y104 HydrophobicContact CD2-CD1 3.65Å; L26-Y104 HydrophobicContact CD2-CE1 3.91Å; L26-Y104 HydrophobicContact CG-CD1 4.03Å; M27-Y104 HydrophobicContact SD-CE1 3.88Å; I75-Y104 HydrophobicContact CD1-CD1 4.03Å; I75-Y104 HydrophobicContact CD1-CD2 4.18Å; I75-Y104 HydrophobicContact CD1-CE1 4.49Å; I75-Y104 HydrophobicContact CD1-CG 3.84Å; I75-Y104 HydrophobicContact CG2-CD2 4.44Å; I75-Y104 HydrophobicContact CG2-CE2 4.21Å; V96-Y104 WeakPolarHBondContact CA-O 3.46Å; I97-Y104 HydrophobicContact CB-CD2 4.3Å; I97-Y104 HydrophobicContact CG2-CD2 4.48Å; I97-Y104 PolarHBondContact N-O 3.08Å; I97-Y104 WeakPolarHBondContact O-CD2 3.43Å; I97-Y104 PolarHBondContact O-N 3.3Å; Q99-Y104 HydrophobicContact CB-CE2 4.45Å; R102-Y104 HydrophobicContact CB-CE2 4.07Å; R102-Y104 WeakPolarHBondContact CD-OH 3.49Å
105Y89.8Confident85.6Confident31 Ų3154.4 Ų54.412%0.12226%0.257CS..EExtended strand (participates in β ladder)trans-92129.1179.7-69.3-90.1000110.9T22 Y23 E85 V96 K103T22-Y105 WeakPolarHBondContact CB-O 3.46Å; T22-Y105 PolarHBondContact OG1-O 3.01Å; Y23-Y105 HydrophobicContact CE2-CD2 4.35Å; Y23-Y105 HydrophobicContact CE2-CG 4.21Å; E85-Y105 HydrophobicContact CG-CE1 4.34Å; V96-Y105 HydrophobicContact CB-CD1 4.14Å; V96-Y105 HydrophobicContact CB-CE1 4.07Å; V96-Y105 HydrophobicContact CG2-CD1 4.12Å; V96-Y105 HydrophobicContact CG2-CD2 4.49Å; V96-Y105 HydrophobicContact CG2-CE1 3.92Å; V96-Y105 HydrophobicContact CG2-CE2 4.3Å; V96-Y105 HydrophobicContact CG2-CG 4.4Å; K103-Y105 HydrophobicContact CB-CD2 4.42Å; K103-Y105 HydrophobicContact CB-CE2 3.79Å; K103-Y105 HydrophobicContact CD-CE2 4.31Å; K103-Y105 WeakPolarHBondContact CD-OH 3.26Å
106F92.8Very high85.3Confident0 Ų057.5 Ų57.50%027%0.274CS..EExtended strand (participates in β ladder)trans-127.7154.2173.2-64.3-79.7000109.1L20 L21 T22 M57 L59 I75 P94 F95 I97L20-F106 HydrophobicContact CB-CD1 4.36Å; L20-F106 HydrophobicContact CD1-CB 4.21Å; L20-F106 HydrophobicContact CD1-CD1 3.87Å; L20-F106 HydrophobicContact CD1-CG 4.18Å; L21-F106 CarbonylContact O-C 3.57Å; L21-F106 WeakPolarHBondContact O-CA 3.21Å; T22-F106 HydrophobicContact CG2-CE1 4.42Å; M57-F106 HydrophobicContact CE-CD1 3.84Å; M57-F106 HydrophobicContact CE-CD2 4.05Å; M57-F106 HydrophobicContact CE-CE1 3.38Å; M57-F106 HydrophobicContact CE-CE2 3.59Å; M57-F106 HydrophobicContact CE-CG 4.16Å; M57-F106 HydrophobicContact CE-CZ 3.25Å; L59-F106 HydrophobicContact CD1-CE1 3.92Å; L59-F106 HydrophobicContact CD1-CZ 4.05Å; L59-F106 HydrophobicContact CD2-CE1 3.95Å; L59-F106 HydrophobicContact CD2-CZ 4.47Å; I75-F106 HydrophobicContact CD1-CE2 3.95Å; I75-F106 HydrophobicContact CD1-CZ 3.65Å; P94-F106 CarbonylContact C-O 3.6Å; P94-F106 WeakPolarHBondContact CA-O 3.39Å; F95-F106 HydrophobicContact CD1-CB 4.05Å; F95-F106 HydrophobicContact CD2-CB 4.15Å; F95-F106 HydrophobicContact CD2-CD2 4.39Å; F95-F106 HydrophobicContact CE1-CB 3.53Å; F95-F106 HydrophobicContact CE2-CB 3.64Å; F95-F106 AromaticContact CE2-CD2 3.72Å; F95-F106 HydrophobicContact CE2-CD2 3.72Å; F95-F106 AromaticContact CE2-CG 3.95Å; F95-F106 HydrophobicContact CE2-CG 3.95Å; F95-F106 HydrophobicContact CG-CB 4.35Å; F95-F106 HydrophobicContact CZ-CB 3.32Å; F95-F106 HydrophobicContact CZ-CD2 4.11Å; F95-F106 AromaticContact CZ-CG 3.85Å; F95-F106 HydrophobicContact CZ-CG 3.85Å; F95-F106 PolarHBondContact N-O 2.97Å; F95-F106 PolarHBondContact O-N 3.37Å; F95-F106 VanDerWaalsContact O-O 3.05Å; I97-F106 HydrophobicContact CD1-CD2 4.07Å; I97-F106 HydrophobicContact CD1-CE2 3.75Å; I97-F106 HydrophobicContact CG1-CD2 4.27Å; I97-F106 HydrophobicContact CG1-CE2 4.25Å
107S92.5Very high85.4Confident0 Ų057.4 Ų57.40%027%0.273CS..EExtended strand (participates in β ladder)trans-135136.9170.9-179.60000110.2L21 P92 Y93L21-S107 PolarHBondContact N-O 2.9Å; L21-S107 PolarHBondContact O-N 2.84Å; P92-S107 WeakPolarHBondContact CD-OG 3.39Å; Y93-S107 PolarHBondContact N-OG 3.06Å; Y93-S107 WeakPolarHBondContact O-CA 3.45Å; Y93-S107 PolarHBondContact O-OG 3.37Å
108C92.3Very high85.2Confident2 Ų258.1 Ų58.11%0.01428%0.277CS..EExtended strand (participates in β ladder)trans-79.8163.6169-60.50000110.1Y93 A110 D113Y93-C108 PolarHBondContact O-N 3Å; Y93-C108 VanDerWaalsContact O-N 3.08Å; C108-A110 VanDerWaalsContact CB-O 3.27Å; C108-A110 WeakPolarHBondContact CB-O 3.45Å; C108-D113 HydrophobicContact CB-CB 3.87Å
109F88.4Confident85.2Confident117 Ų11763.2 Ų63.251%0.51329%0.292SS..SBendtrans-87-19171.5-68.6-82.3000112.7M19 L21 T47 Y93M19-F109 HydrophobicContact CB-CD2 4.31Å; M19-F109 HydrophobicContact CB-CE2 3.93Å; L21-F109 HydrophobicContact CB-CZ 4.4Å; T47-F109 HydrophobicContact CG2-CE2 4.08Å; T47-F109 HydrophobicContact CG2-CZ 3.82Å; Y93-F109 WeakPolarHBondContact CE2-O 3.5Å
110A85.7Confident85.4Confident29 Ų2963 Ų6324%0.2429%0.293CS..SBendtrans-126.3144.4174.700000110.3C108 E112 D113C108-A110 VanDerWaalsContact CB-O 3.27Å; C108-A110 WeakPolarHBondContact CB-O 3.45Å; A110-E112 VanDerWaalsContact C-N 3.29Å; A110-E112 HydrophobicContact CB-CG 4.03Å; A110-E112 PolarHBondContact O-N 2.92Å; A110-D113 PolarHBondContact O-N 3.22Å
111E83.4Confident85.9Confident106 Ų10657 Ų5750%0.49527%0.27SS..Hα-helixtrans-63.3-35.8-179.3-167.6-175.9166.300112.2Y93 D113 R114Y93-E111 HydrophobicContact CD1-CB 3.76Å; Y93-E111 HydrophobicContact CD1-CG 3.97Å; Y93-E111 HydrophobicContact CE1-CB 3.75Å; Y93-E111 HydrophobicContact CE1-CG 4.19Å; Y93-E111 HydrophobicContact CG-CB 4.34Å; E111-D113 PolarHBondContact O-N 3.01Å; E111-R114 WeakPolarHBondContact O-CG 3.48Å; E111-R114 PolarHBondContact O-N 3.37Å; E111-R114 IonicContact OE1-CZ 2.88Å; E111-R114 IonicContact OE1-NE 3.26Å; E111-R114 IonicContact OE1-NH2 3.37Å; E111-R114 PolarHBondContact OE1-NH2 3.42Å
112E80.4Confident86.2Confident157 Ų15752.9 Ų52.973%0.73425%0.247SC*.Hα-helixtrans-61.4-30.2-178.555.2-170.7-176.600113.5A110 R114A110-E112 VanDerWaalsContact C-N 3.29Å; A110-E112 HydrophobicContact CB-CG 4.03Å; A110-E112 PolarHBondContact O-N 2.92Å; E112-R114 PolarHBondContact O-N 2.77Å
113D86.2Confident86Confident54 Ų5449.2 Ų49.229%0.28924%0.242SC..Hα-helixtrans-75.8-23.7-175.7-79.2-40.2000114.3C108 A110 E111 D116 W117C108-D113 HydrophobicContact CB-CB 3.87Å; A110-D113 PolarHBondContact O-N 3.22Å; E111-D113 PolarHBondContact O-N 3.01Å; D113-D116 PolarHBondContact O-N 3.37Å; D113-W117 PolarHBondContact O-N 2.95Å
114R86Confident85.7Confident47 Ų4745.9 Ų45.918%0.17723%0.228CC..Hα-helixtrans-66.4-42.6-172.272.5-166.2174.4144.8-7112.3L84 E111 E112 D116 W117 V118L84-R114 HydrophobicContact CD1-CG 4.34Å; L84-R114 HydrophobicContact CD2-CB 3.83Å; L84-R114 HydrophobicContact CD2-CG 3.52Å; E111-R114 WeakPolarHBondContact O-CG 3.48Å; E111-R114 PolarHBondContact O-N 3.37Å; E111-R114 IonicContact OE1-CZ 2.88Å; E111-R114 IonicContact OE1-NE 3.26Å; E111-R114 IonicContact OE1-NH2 3.37Å; E111-R114 PolarHBondContact OE1-NH2 3.42Å; E112-R114 PolarHBondContact O-N 2.77Å; R114-D116 VanDerWaalsContact C-N 3.29Å; R114-D116 PolarHBondContact O-N 3.26Å; R114-W117 PolarHBondContact O-N 2.92Å; R114-V118 WeakPolarHBondContact O-CG2 3.25Å; R114-V118 PolarHBondContact O-N 3.06Å
115A81.1Confident85.1Confident27 Ų2745.1 Ų45.122%0.22323%0.225CC..Hα-helixtrans-67.3-35.3179.200000111R119A115-R119 WeakPolarHBondContact O-CB 3.39Å; A115-R119 WeakPolarHBondContact O-CG 3.27Å; A115-R119 PolarHBondContact O-N 3.35Å
116D85.2Confident84.3Confident66 Ų6650.5 Ų50.535%0.35325%0.247SC..Hα-helixtrans-66.3-40.7175.4-767.8000112.1K16 D113 R114 R119 A120K16-D116 IonicContact NZ-OD2 2.71Å; D113-D116 PolarHBondContact O-N 3.37Å; R114-D116 VanDerWaalsContact C-N 3.29Å; R114-D116 PolarHBondContact O-N 3.26Å; D116-R119 PolarHBondContact O-N 3.42Å; D116-R119 IonicContact OD1-CZ 3.82Å; D116-R119 IonicContact OD1-NH1 3.76Å; D116-R119 PolarHBondContact OD1-NH1 3.39Å; D116-R119 IonicContact OD1-NH2 2.97Å; D116-A120 VanDerWaalsContact O-CB 3.24Å; D116-A120 WeakPolarHBondContact O-CB 3.31Å; D116-A120 PolarHBondContact O-N 2.92Å
117W90.8Very high83Confident0 Ų055.4 Ų55.40%027%0.269CS..Hα-helixtrans-63.1-47.9174-91.5108.5000112.3K16 S18 L20 A50 L52 M57 F95 D113 R114 R119 A120 I121K16-W117 HydrophobicContact CB-CH2 4.38Å; K16-W117 HydrophobicContact CB-CZ3 4.41Å; K16-W117 HydrophobicContact CD-CD2 3.74Å; K16-W117 HydrophobicContact CD-CE3 4.12Å; K16-W117 HydrophobicContact CD-CG 3.98Å; K16-W117 HydrophobicContact CD-CZ2 4.4Å; K16-W117 VanDerWaalsContact CE-CG 3.5Å; K16-W117 HydrophobicContact CG-CD2 4.33Å; K16-W117 HydrophobicContact CG-CH2 4.34Å; K16-W117 HydrophobicContact CG-CZ2 4.12Å; S18-W117 VanDerWaalsContact OG-CE2 3.25Å; S18-W117 WeakPolarHBondContact OG-CZ2 3.34Å; S18-W117 PolarHBondContact OG-NE1 3.49Å; L20-W117 HydrophobicContact CD1-CD2 4.33Å; L20-W117 HydrophobicContact CD1-CH2 4.37Å; L20-W117 HydrophobicContact CD1-CZ2 3.95Å; L20-W117 HydrophobicContact CG-CZ2 4.27Å; A50-W117 HydrophobicContact CB-CH2 3.75Å; A50-W117 HydrophobicContact CB-CZ2 3.98Å; L52-W117 HydrophobicContact CB-CZ3 4.07Å; M57-W117 HydrophobicContact SD-CZ3 4.21Å; F95-W117 HydrophobicContact CD1-CB 4.31Å; F95-W117 HydrophobicContact CE1-CB 3.77Å; F95-W117 AromaticContact CE1-CG 3.94Å; F95-W117 HydrophobicContact CE1-CG 3.94Å; F95-W117 HydrophobicContact CE2-CB 4.34Å; F95-W117 HydrophobicContact CZ-CB 3.77Å; F95-W117 HydrophobicContact CZ-CD2 4.19Å; F95-W117 HydrophobicContact CZ-CE3 4.47Å; F95-W117 AromaticContact CZ-CG 3.9Å; F95-W117 HydrophobicContact CZ-CG 3.9Å; D113-W117 PolarHBondContact O-N 2.95Å; R114-W117 PolarHBondContact O-N 2.92Å; W117-R119 VanDerWaalsContact C-N 3.34Å; W117-R119 PolarHBondContact O-N 2.95Å; W117-A120 PolarHBondContact O-N 3.3Å; W117-I121 HydrophobicContact CE3-CD1 4.11Å; W117-I121 HydrophobicContact CE3-CG1 4.28Å; W117-I121 WeakPolarHBondContact O-CB 3.33Å; W117-I121 WeakPolarHBondContact O-CD1 3.35Å; W117-I121 VanDerWaalsContact O-CG1 3.29Å; W117-I121 WeakPolarHBondContact O-CG1 3.42Å; W117-I121 PolarHBondContact O-N 2.92Å
118V87.6Confident81.9Confident16 Ų1659.5 Ų59.510%0.09729%0.289CS..Hα-helixtrans-58.4-46.2176.3170.30000111A82 L84 F95 R114 A120 I121 I122A82-V118 HydrophobicContact CB-CB 4.49Å; A82-V118 HydrophobicContact CB-CG1 4.1Å; A82-V118 HydrophobicContact CB-CG2 4.38Å; A82-V118 WeakPolarHBondContact O-CG1 3.43Å; L84-V118 HydrophobicContact CD2-CG2 3.65Å; L84-V118 HydrophobicContact CG-CG2 4.36Å; F95-V118 HydrophobicContact CB-CG2 3.88Å; F95-V118 HydrophobicContact CG-CG2 4.34Å; R114-V118 WeakPolarHBondContact O-CG2 3.25Å; R114-V118 PolarHBondContact O-N 3.06Å; V118-A120 PolarHBondContact O-N 2.96Å; V118-I121 PolarHBondContact O-N 2.88Å; V118-I122 HydrophobicContact CG1-CD1 3.61Å; V118-I122 HydrophobicContact CG1-CG1 4.41Å; V118-I122 WeakPolarHBondContact O-CB 3.45Å; V118-I122 VanDerWaalsContact O-CG1 3.23Å; V118-I122 WeakPolarHBondContact O-CG1 3.38Å; V118-I122 PolarHBondContact O-N 3.09Å
119R82.1Confident80.7Confident144 Ų14462.5 Ų62.554%0.54331%0.305SS..Hα-helixtrans-61.3-43.9175.9-75.2-171.1-125.6105.51.9112.1A115 D116 W117 S123A115-R119 WeakPolarHBondContact O-CB 3.39Å; A115-R119 WeakPolarHBondContact O-CG 3.27Å; A115-R119 PolarHBondContact O-N 3.35Å; D116-R119 PolarHBondContact O-N 3.42Å; D116-R119 IonicContact OD1-CZ 3.82Å; D116-R119 IonicContact OD1-NH1 3.76Å; D116-R119 PolarHBondContact OD1-NH1 3.39Å; D116-R119 IonicContact OD1-NH2 2.97Å; W117-R119 VanDerWaalsContact C-N 3.34Å; W117-R119 PolarHBondContact O-N 2.95Å; R119-S123 VanDerWaalsContact O-CB 3.31Å; R119-S123 WeakPolarHBondContact O-CB 3.45Å; R119-S123 PolarHBondContact O-N 3.5Å; R119-S123 PolarHBondContact O-OG 2.9Å
120A85.4Confident79.7Confident12 Ų1259.4 Ų59.410%0.09930%0.298CS..Hα-helixtrans-62.1-48.217900000111.5K16 L52 D116 W117 V118 S123 C124K16-A120 HydrophobicContact CB-CB 4.16Å; K16-A120 HydrophobicContact CD-CB 3.93Å; L52-A120 HydrophobicContact CD2-CB 3.92Å; D116-A120 VanDerWaalsContact O-CB 3.24Å; D116-A120 WeakPolarHBondContact O-CB 3.31Å; D116-A120 PolarHBondContact O-N 2.92Å; W117-A120 PolarHBondContact O-N 3.3Å; V118-A120 PolarHBondContact O-N 2.96Å; A120-S123 PolarHBondContact O-N 3.45Å; A120-S123 PolarHBondContact O-OG 3.3Å; A120-C124 WeakPolarHBondContact O-CB 3.09Å; A120-C124 PolarHBondContact O-N 3.41Å; A120-C124 VanDerWaalsContact O-N 3.14Å; A120-C124 PolarHBondContact O-SG 2.88Å
121I87.3Confident78.7Confident0 Ų062 Ų620%031%0.311CS..Hα-helixtrans-61.2-48.7178.6-69.3158.9000111L52 L77 A82 F95 I97 W117 V118 S123 C124 S125L52-I121 HydrophobicContact CD2-CG1 4.43Å; L77-I121 HydrophobicContact CD1-CG2 4Å; L77-I121 HydrophobicContact CD2-CG2 4.07Å; A82-I121 HydrophobicContact CB-CB 4.17Å; A82-I121 HydrophobicContact CB-CG2 3.79Å; F95-I121 HydrophobicContact CD2-CD1 4.24Å; F95-I121 HydrophobicContact CE2-CD1 3.57Å; F95-I121 HydrophobicContact CZ-CD1 4.31Å; I97-I121 HydrophobicContact CD1-CD1 3.58Å; I97-I121 HydrophobicContact CD1-CG1 4.35Å; I97-I121 HydrophobicContact CD1-CG2 4.42Å; I97-I121 HydrophobicContact CG1-CD1 4Å; W117-I121 HydrophobicContact CE3-CD1 4.11Å; W117-I121 HydrophobicContact CE3-CG1 4.28Å; W117-I121 WeakPolarHBondContact O-CB 3.33Å; W117-I121 WeakPolarHBondContact O-CD1 3.35Å; W117-I121 VanDerWaalsContact O-CG1 3.29Å; W117-I121 WeakPolarHBondContact O-CG1 3.42Å; W117-I121 PolarHBondContact O-N 2.92Å; V118-I121 PolarHBondContact O-N 2.88Å; I121-S123 VanDerWaalsContact C-N 3.28Å; I121-S123 PolarHBondContact O-N 2.97Å; I121-C124 CarbonylContact O-C 3.48Å; I121-C124 PolarHBondContact O-N 2.71Å; I121-S125 PolarHBondContact O-N 2.85Å; I121-S125 VanDerWaalsContact O-N 3.09Å
122I79.5Confident77.7Confident77 Ų7758.2 Ų58.240%0.39530%0.3SS..Hα-helixtrans-59.9-41.3177.8-67.6168.3000110.7A82 V118 C124 S125 M128A82-I122 HydrophobicContact CB-CG1 4.19Å; V118-I122 HydrophobicContact CG1-CD1 3.61Å; V118-I122 HydrophobicContact CG1-CG1 4.41Å; V118-I122 WeakPolarHBondContact O-CB 3.45Å; V118-I122 VanDerWaalsContact O-CG1 3.23Å; V118-I122 WeakPolarHBondContact O-CG1 3.38Å; V118-I122 PolarHBondContact O-N 3.09Å; I122-C124 PolarHBondContact O-N 2.82Å; I122-S125 PolarHBondContact O-N 3.24Å; I122-S125 PolarHBondContact O-OG 3.12Å; I122-M128 WeakPolarHBondContact O-CB 3.49Å
123S75Confident77.1Confident58 Ų5854.6 Ų54.641%0.40629%0.288SS..Hα-helixtrans-68-17.5178.976.50000114.2R119 A120 I121R119-S123 VanDerWaalsContact O-CB 3.31Å; R119-S123 WeakPolarHBondContact O-CB 3.45Å; R119-S123 PolarHBondContact O-N 3.5Å; R119-S123 PolarHBondContact O-OG 2.9Å; A120-S123 PolarHBondContact O-N 3.45Å; A120-S123 PolarHBondContact O-OG 3.3Å; I121-S123 VanDerWaalsContact C-N 3.28Å; I121-S123 PolarHBondContact O-N 2.97Å
124C80Confident76.1Confident0 Ų055.2 Ų55.20%029%0.294CS..THydrogen-bonded Turntrans-107.91.3-176.5-68.20000113.2K15 L52 G54 N55 L77 A120 I121 I122K15-C124 VanDerWaalsContact CG-SG 3.6Å; L52-C124 HydrophobicContact CD1-CB 4.25Å; L52-C124 HydrophobicContact CD2-CB 4.03Å; L52-C124 HydrophobicContact CG-CB 4.37Å; G54-C124 VanDerWaalsContact O-CB 3.23Å; G54-C124 WeakPolarHBondContact O-CB 3.44Å; N55-C124 WeakPolarHBondContact CA-O 3.27Å; N55-C124 VanDerWaalsContact CB-O 3.25Å; N55-C124 WeakPolarHBondContact CB-O 3.44Å; L77-C124 HydrophobicContact CD1-CB 4.41Å; A120-C124 WeakPolarHBondContact O-CB 3.09Å; A120-C124 PolarHBondContact O-N 3.41Å; A120-C124 VanDerWaalsContact O-N 3.14Å; A120-C124 PolarHBondContact O-SG 2.88Å; I121-C124 CarbonylContact O-C 3.48Å; I121-C124 PolarHBondContact O-N 2.71Å; I122-C124 PolarHBondContact O-N 2.82Å
125S75.7Confident75Confident5 Ų559.7 Ų59.74%0.03531%0.311CS..SBendtrans-60.3150172.475.20000109.8L77 I121 I122 E127 M128 L129L77-S125 WeakPolarHBondContact O-CA 3.31Å; I121-S125 PolarHBondContact O-N 2.85Å; I121-S125 VanDerWaalsContact O-N 3.09Å; I122-S125 PolarHBondContact O-N 3.24Å; I122-S125 PolarHBondContact O-OG 3.12Å; S125-E127 PolarHBondContact O-N 2.82Å; S125-M128 PolarHBondContact O-N 3.24Å; S125-M128 PolarHBondContact OG-N 3.34Å; S125-L129 PolarHBondContact O-N 3.31Å
126Y72.4Confident74.1Confident144 Ų14464.6 Ų64.657%0.56533%0.327SS*.Hα-helixtrans-51.1-41.6175.1174.3-94.9000111.8L77 M128 L129 S130L77-Y126 PolarHBondContact O-N 2.85Å; Y126-M128 PolarHBondContact O-N 3.01Å; Y126-L129 PolarHBondContact O-N 2.76Å; Y126-S130 VanDerWaalsContact O-CB 3.31Å; Y126-S130 WeakPolarHBondContact O-CB 3.43Å; Y126-S130 PolarHBondContact O-N 2.85Å
127E66.4Low73.1Confident103 Ų10367.5 Ų67.548%0.48134%0.338SS..Hα-helixtrans-59.4-44.4178.3-63.7165.7172.100111.6S125 S130 V131S125-E127 PolarHBondContact O-N 2.82Å; E127-S130 WeakPolarHBondContact O-CB 3.43Å; E127-S130 PolarHBondContact O-N 2.99Å; E127-V131 WeakPolarHBondContact O-CG2 3.5Å; E127-V131 PolarHBondContact O-N 3.13Å
128M68.3Low71.5Confident85 Ų8572.5 Ų72.542%0.41936%0.362SS..Hα-helixtrans-75.9-34.7-178.2-156.852.45600112.8I122 S125 Y126 V131 G132I122-M128 WeakPolarHBondContact O-CB 3.49Å; S125-M128 PolarHBondContact O-N 3.24Å; S125-M128 PolarHBondContact OG-N 3.34Å; Y126-M128 PolarHBondContact O-N 3.01Å; M128-V131 PolarHBondContact O-N 2.85Å; M128-V131 HydrophobicContact SD-CB 4.43Å; M128-G132 PolarHBondContact O-N 2.84Å
129L67.6Low70.2Confident65 Ų6575.4 Ų75.434%0.3437%0.374SS..Hα-helixtrans-64.5-41.2170.7-70.4174.7000111.4N55 S125 Y126 V131 G132 V133N55-L129 HydrophobicContact CB-CD1 3.81Å; S125-L129 PolarHBondContact O-N 3.31Å; Y126-L129 PolarHBondContact O-N 2.76Å; L129-V131 VanDerWaalsContact C-N 3.35Å; L129-V131 PolarHBondContact O-N 2.8Å; L129-G132 WeakPolarHBondContact O-CA 3.41Å; L129-G132 PolarHBondContact O-N 2.79Å; L129-G132 VanDerWaalsContact O-N 3.12Å; L129-V133 WeakPolarHBondContact O-CG2 3.49Å; L129-V133 PolarHBondContact O-N 2.76Å
130S66.8Low69.4Low52 Ų5273.5 Ų73.536%0.36437%0.374SS..Hα-helixtrans-59.1-46174.5-176.90000111.1Y126 E127 G132 V133 V134Y126-S130 VanDerWaalsContact O-CB 3.31Å; Y126-S130 WeakPolarHBondContact O-CB 3.43Å; Y126-S130 PolarHBondContact O-N 2.85Å; E127-S130 WeakPolarHBondContact O-CB 3.43Å; E127-S130 PolarHBondContact O-N 2.99Å; S130-G132 VanDerWaalsContact C-N 3.31Å; S130-G132 PolarHBondContact O-N 2.84Å; S130-V133 PolarHBondContact O-N 2.7Å; S130-V134 WeakPolarHBondContact O-CG2 3.37Å; S130-V134 PolarHBondContact O-N 3.38Å
131V64.8Low68Low85 Ų8578.8 Ų78.852%0.51539%0.392SS..Hα-helixtrans-59.8-41.9173.3172.20000111.4E127 M128 L129 V134 R135E127-V131 WeakPolarHBondContact O-CG2 3.5Å; E127-V131 PolarHBondContact O-N 3.13Å; M128-V131 PolarHBondContact O-N 2.85Å; M128-V131 HydrophobicContact SD-CB 4.43Å; L129-V131 VanDerWaalsContact C-N 3.35Å; L129-V131 PolarHBondContact O-N 2.8Å; V131-V134 PolarHBondContact O-N 3.02Å; V131-R135 WeakPolarHBondContact O-CB 3.43Å; V131-R135 PolarHBondContact O-N 2.83Å
132G63.3Low66.4Low25 Ų2581.5 Ų81.526%0.25841%0.405SS..Hα-helixtrans-61.8-42.1176.300000113.4M128 L129 S130 R135 F136M128-G132 PolarHBondContact O-N 2.84Å; L129-G132 WeakPolarHBondContact O-CA 3.41Å; L129-G132 PolarHBondContact O-N 2.79Å; L129-G132 VanDerWaalsContact O-N 3.12Å; S130-G132 VanDerWaalsContact C-N 3.31Å; S130-G132 PolarHBondContact O-N 2.84Å; G132-R135 PolarHBondContact O-N 3.06Å; G132-F136 WeakPolarHBondContact O-CD2 3.37Å; G132-F136 PolarHBondContact O-N 2.83Å
133V67.3Low65.5Low82 Ų8284.6 Ų84.650%0.49742%0.415SS..Hα-helixtrans-66-45.9176.6171.50000111L129 S130 R135 F136 Q137L129-V133 WeakPolarHBondContact O-CG2 3.49Å; L129-V133 PolarHBondContact O-N 2.76Å; S130-V133 PolarHBondContact O-N 2.7Å; V133-R135 VanDerWaalsContact C-N 3.26Å; V133-R135 PolarHBondContact O-N 3.28Å; V133-F136 PolarHBondContact O-N 2.93Å; V133-F136 VanDerWaalsContact O-N 3.12Å; V133-Q137 PolarHBondContact O-N 3.44Å
134V65.1Low65Low66 Ų6687.8 Ų87.840%0.442%0.424SS..Hα-helixtrans-56.5-44.9174.1171.50000110S130 V131 F136 Q137 E138S130-V134 WeakPolarHBondContact O-CG2 3.37Å; S130-V134 PolarHBondContact O-N 3.38Å; V131-V134 PolarHBondContact O-N 3.02Å; V134-F136 PolarHBondContact O-N 3.25Å; V134-Q137 WeakPolarHBondContact O-CB 3.47Å; V134-Q137 PolarHBondContact O-N 3.2Å; V134-E138 WeakPolarHBondContact O-CG 3.47Å; V134-E138 PolarHBondContact O-N 3.36Å
135R62.5Low63.7Low142 Ų14288.1 Ų88.154%0.53643%0.426SS..Hα-helixtrans-63.6-36.5176.6-165.1-179.9-173.1-178.63.2113.3V131 G132 V133 Q139V131-R135 WeakPolarHBondContact O-CB 3.43Å; V131-R135 PolarHBondContact O-N 2.83Å; G132-R135 PolarHBondContact O-N 3.06Å; V133-R135 VanDerWaalsContact C-N 3.26Å; V133-R135 PolarHBondContact O-N 3.28Å; R135-Q139 VanDerWaalsContact O-CG 3.29Å; R135-Q139 WeakPolarHBondContact O-CG 3.36Å; R135-Q139 PolarHBondContact O-N 2.97Å
136F63.1Low62.6Low130 Ų13093.4 Ų93.457%0.5745%0.445SS*.Hα-helixtrans-70.2-39173.8-79.5-55.3000112.2G132 V133 V134 E138 Q139 I140G132-F136 WeakPolarHBondContact O-CD2 3.37Å; G132-F136 PolarHBondContact O-N 2.83Å; V133-F136 PolarHBondContact O-N 2.93Å; V133-F136 VanDerWaalsContact O-N 3.12Å; V134-F136 PolarHBondContact O-N 3.25Å; F136-E138 VanDerWaalsContact C-N 3.32Å; F136-Q139 PolarHBondContact O-N 2.91Å; F136-I140 WeakPolarHBondContact O-CG1 3.12Å; F136-I140 PolarHBondContact O-N 2.98Å
137Q63.9Low62.1Low126 Ų12693.2 Ų93.259%0.58945%0.454SS*.Hα-helixtrans-59.6-45.3171.9-75.5-179-19.200110.6V133 V134 Q139 I140 Y141V133-Q137 PolarHBondContact O-N 3.44Å; V134-Q137 WeakPolarHBondContact O-CB 3.47Å; V134-Q137 PolarHBondContact O-N 3.2Å; Q137-Q139 PolarHBondContact O-N 3.48Å; Q137-I140 PolarHBondContact O-N 3.37Å; Q137-Y141 VanDerWaalsContact O-CB 3.28Å; Q137-Y141 WeakPolarHBondContact O-CB 3.38Å; Q137-Y141 PolarHBondContact O-N 2.83Å
138E56.8Low61.9Low105 Ų10594.4 Ų94.449%0.49146%0.457SS..Hα-helixtrans-57.2-46.8172.8-72170.9169.400111.4V134 F136 I140 Y141 E142V134-E138 WeakPolarHBondContact O-CG 3.47Å; V134-E138 PolarHBondContact O-N 3.36Å; F136-E138 VanDerWaalsContact C-N 3.32Å; E138-I140 PolarHBondContact O-N 3.4Å; E138-Y141 PolarHBondContact O-N 3.27Å; E138-E142 WeakPolarHBondContact O-CB 3.4Å; E138-E142 VanDerWaalsContact O-CG 3.3Å; E138-E142 WeakPolarHBondContact O-CG 3.27Å; E138-E142 PolarHBondContact O-N 3.45Å
139Q61.2Low61.4Low77 Ų7792.7 Ų92.736%0.3645%0.446SS..Hα-helixtrans-64.7-37.4177.9-75.8177.26.800114R135 F136 Q137 K143R135-Q139 VanDerWaalsContact O-CG 3.29Å; R135-Q139 WeakPolarHBondContact O-CG 3.36Å; R135-Q139 PolarHBondContact O-N 2.97Å; F136-Q139 PolarHBondContact O-N 2.91Å; Q137-Q139 PolarHBondContact O-N 3.48Å; Q139-K143 WeakPolarHBondContact O-CG 3.37Å; Q139-K143 PolarHBondContact O-N 3.44Å
140I64.4Low60.7Low104 Ų10491.5 Ų91.553%0.53345%0.45SS..Hα-helixtrans-67.2-45.8175.7-70.8168.6000109.5F136 Q137 E138 K143 Q144F136-I140 WeakPolarHBondContact O-CG1 3.12Å; F136-I140 PolarHBondContact O-N 2.98Å; Q137-I140 PolarHBondContact O-N 3.37Å; E138-I140 PolarHBondContact O-N 3.4Å; I140-K143 WeakPolarHBondContact O-CB 3.32Å; I140-K143 PolarHBondContact O-N 2.96Å; I140-Q144 PolarHBondContact O-N 2.77Å
141Y57.1Low59.8Low123 Ų12399.8 Ų99.848%0.48247%0.474SS..Hα-helixtrans-60.4-47.3176.3-172.6-110.5000110.9Q137 E138 K143 Q144 L145Q137-Y141 VanDerWaalsContact O-CB 3.28Å; Q137-Y141 WeakPolarHBondContact O-CB 3.38Å; Q137-Y141 PolarHBondContact O-N 2.83Å; E138-Y141 PolarHBondContact O-N 3.27Å; Y141-K143 VanDerWaalsContact C-N 3.31Å; Y141-K143 PolarHBondContact O-N 3.17Å; Y141-Q144 PolarHBondContact O-N 3.08Å; Y141-Q144 VanDerWaalsContact O-N 3.1Å; Y141-L145 HydrophobicContact CD1-CD1 3.69Å; Y141-L145 HydrophobicContact CD1-CG 4.31Å; Y141-L145 HydrophobicContact CE1-CD1 3.5Å; Y141-L145 VanDerWaalsContact CE1-CD1 3.5Å; Y141-L145 HydrophobicContact CE1-CD2 4.45Å; Y141-L145 HydrophobicContact CE1-CG 4.16Å; Y141-L145 HydrophobicContact CG-CD1 4.49Å; Y141-L145 VanDerWaalsContact O-CG 3.31Å; Y141-L145 WeakPolarHBondContact O-CG 3.49Å; Y141-L145 PolarHBondContact O-N 3.39Å
142E53.2Low59Low57 Ų5798.9 Ų98.927%0.26647%0.465SS..Hα-helixtrans-52.3-45.6171.3-80.2-179.6-162.200112.2E138 Q144 L145 R146 H275E138-E142 WeakPolarHBondContact O-CB 3.4Å; E138-E142 VanDerWaalsContact O-CG 3.3Å; E138-E142 WeakPolarHBondContact O-CG 3.27Å; E138-E142 PolarHBondContact O-N 3.45Å; E142-Q144 PolarHBondContact O-N 3.4Å; E142-L145 PolarHBondContact O-N 2.98Å; E142-R146 VanDerWaalsContact O-CG 3.31Å; E142-R146 WeakPolarHBondContact O-CG 3.45Å; E142-R146 PolarHBondContact O-N 3.49Å; E142-R146 IonicContact OE2-NH2 2.7Å; E142-R146 PolarHBondContact OE2-NH2 2.91Å; E142-H275 IonicContact OE2-CE1 3.1Å; E142-H275 PolarHBondContact OE2-CE1 3.5Å; E142-H275 IonicContact OE2-NE2 3.37Å
143K60.1Low58Low142 Ų142107.8 Ų107.862%0.61749%0.491SS*.Hα-helixtrans-63.8-39.2178.3-81.4179.8179.7176.10112.6Q139 I140 Y141 R146 N147Q139-K143 WeakPolarHBondContact O-CG 3.37Å; Q139-K143 PolarHBondContact O-N 3.44Å; I140-K143 WeakPolarHBondContact O-CB 3.32Å; I140-K143 PolarHBondContact O-N 2.96Å; Y141-K143 VanDerWaalsContact C-N 3.31Å; Y141-K143 PolarHBondContact O-N 3.17Å; K143-R146 PolarHBondContact O-N 2.93Å; K143-N147 PolarHBondContact O-N 2.93Å
144Q64.5Low56.7Low126 Ų126114.8 Ų114.859%0.58951%0.509SS*.Hα-helixtrans-65.1-42.6174.9-70.7-179.3-19.500111.1I140 Y141 E142 R146 N147 K148I140-Q144 PolarHBondContact O-N 2.77Å; Y141-Q144 PolarHBondContact O-N 3.08Å; Y141-Q144 VanDerWaalsContact O-N 3.1Å; E142-Q144 PolarHBondContact O-N 3.4Å; Q144-R146 PolarHBondContact O-N 3.47Å; Q144-N147 WeakPolarHBondContact O-CB 3.48Å; Q144-N147 PolarHBondContact O-N 3.22Å; Q144-N147 VanDerWaalsContact O-N 3.16Å; Q144-K148 PolarHBondContact O-N 3.29Å
145L52.9Low55.6Low7 Ų7115.5 Ų115.54%0.03751%0.51CS..Hα-helixtrans-61.6-41.2175.7-66.9176.5000112.5Y141 E142 N147 K148 Y149 E269 A273Y141-L145 HydrophobicContact CD1-CD1 3.69Å; Y141-L145 HydrophobicContact CD1-CG 4.31Å; Y141-L145 HydrophobicContact CE1-CD1 3.5Å; Y141-L145 VanDerWaalsContact CE1-CD1 3.5Å; Y141-L145 HydrophobicContact CE1-CD2 4.45Å; Y141-L145 HydrophobicContact CE1-CG 4.16Å; Y141-L145 HydrophobicContact CG-CD1 4.49Å; Y141-L145 VanDerWaalsContact O-CG 3.31Å; Y141-L145 WeakPolarHBondContact O-CG 3.49Å; Y141-L145 PolarHBondContact O-N 3.39Å; E142-L145 PolarHBondContact O-N 2.98Å; L145-N147 PolarHBondContact O-N 3.26Å; L145-K148 WeakPolarHBondContact O-CB 3.36Å; L145-K148 PolarHBondContact O-N 3.17Å; L145-Y149 HydrophobicContact CD2-CE2 4.25Å; L145-Y149 VanDerWaalsContact O-CD2 3.29Å; L145-Y149 WeakPolarHBondContact O-CD2 3.48Å; L145-Y149 PolarHBondContact O-N 3.43Å; L145-E269 HydrophobicContact CD1-CG 4.15Å; L145-E269 HydrophobicContact CD2-CG 3.36Å; L145-E269 WeakPolarHBondContact CD2-OE1 3.36Å; L145-E269 HydrophobicContact CG-CG 4.4Å; L145-A273 HydrophobicContact CB-CB 3.68Å; L145-A273 HydrophobicContact CD1-CB 4.16Å; L145-A273 HydrophobicContact CG-CB 4.5Å
146R54Low54.6Low115 Ų115116 Ų11643%0.43452%0.518SS..Hα-helixtrans-55-35.3174.6-74.3175.3-153.7-150.16.6112.6E142 K143 Q144 G150 H275E142-R146 VanDerWaalsContact O-CG 3.31Å; E142-R146 WeakPolarHBondContact O-CG 3.45Å; E142-R146 PolarHBondContact O-N 3.49Å; E142-R146 IonicContact OE2-NH2 2.7Å; E142-R146 PolarHBondContact OE2-NH2 2.91Å; K143-R146 PolarHBondContact O-N 2.93Å; Q144-R146 PolarHBondContact O-N 3.47Å; R146-G150 WeakPolarHBondContact O-CA 3.31Å; R146-G150 PolarHBondContact O-N 3.06Å; R146-H275 PolarHBondContact NE-CD2 3.12Å; R146-H275 PolarHBondContact NE-NE2 3.35Å; R146-H275 PolarHBondContact NH2-CE1 3.43Å; R146-H275 PolarHBondContact NH2-NE2 3.46Å
147N60.9Low53.8Low141 Ų141111.6 Ų111.675%0.75450%0.499SS*.Hα-helixtrans-71.6-38.1177.3-69.1-19.9000111.8K143 Q144 L145K143-N147 PolarHBondContact O-N 2.93Å; Q144-N147 WeakPolarHBondContact O-CB 3.48Å; Q144-N147 PolarHBondContact O-N 3.22Å; Q144-N147 VanDerWaalsContact O-N 3.16Å; L145-N147 PolarHBondContact O-N 3.26Å
148K62.2Low52.4Low127 Ų127111.7 Ų111.755%0.55251%0.511SS*.Hα-helixtrans-64.6-44.1176-171.3179.8172.1-169.60111.7Q144 L145 E269Q144-K148 PolarHBondContact O-N 3.29Å; L145-K148 WeakPolarHBondContact O-CB 3.36Å; L145-K148 PolarHBondContact O-N 3.17Å; K148-E269 WeakPolarHBondContact CD-OE1 3.44Å; K148-E269 IonicContact NZ-OE1 2.78Å; K148-E269 PolarHBondContact NZ-OE1 2.98Å; K148-E269 IonicContact NZ-OE2 3.91Å; K148-E269 PolarHBondContact NZ-OE2 3.29Å
149Y58.9Low51.5Low49 Ų49108.9 Ų108.919%0.19251%0.511CS..THydrogen-bonded Turntrans-96.910.8-176.7-60.7-73.9000114.8L145 R151 L152 E269 F270 A273L145-Y149 HydrophobicContact CD2-CE2 4.25Å; L145-Y149 VanDerWaalsContact O-CD2 3.29Å; L145-Y149 WeakPolarHBondContact O-CD2 3.48Å; L145-Y149 PolarHBondContact O-N 3.43Å; Y149-R151 PolarHBondContact O-N 3Å; Y149-L152 HydrophobicContact CD1-CD1 4Å; Y149-L152 WeakPolarHBondContact O-CB 3.27Å; Y149-L152 PolarHBondContact O-N 3.48Å; Y149-E269 HydrophobicContact CE2-CG 4.16Å; Y149-E269 PolarHBondContact OH-OE1 3.06Å; Y149-F270 HydrophobicContact CD1-CD2 4.28Å; Y149-F270 HydrophobicContact CE1-CD2 4.44Å; Y149-A273 HydrophobicContact CD2-CB 3.85Å; Y149-A273 HydrophobicContact CE2-CB 4.27Å
150G52.7Low50.3Low41 Ų41107.5 Ų107.542%0.42350%0.504SS..G310 helixtrans-56.8-21.8-175.800000115.4R146 L152R146-G150 WeakPolarHBondContact O-CA 3.31Å; R146-G150 PolarHBondContact O-N 3.06Å; G150-L152 PolarHBondContact O-N 3.32Å
151R46.6Very low48.7Very low226 Ų226109 Ų10985%0.85351%0.508SS*.G310 helixtrans-66.7-19.3174.5-68.9-175.6176.8-175.70.8113.6Y149Y149-R151 PolarHBondContact O-N 3Å
152L48.7Very low47.7Very low65 Ų65108 Ų10834%0.3452%0.515SS..G310 helixtrans-88.82.5-175-69.5161.3000114.4Y149 G150 R154 L155 F270Y149-L152 HydrophobicContact CD1-CD1 4Å; Y149-L152 WeakPolarHBondContact O-CB 3.27Å; Y149-L152 PolarHBondContact O-N 3.48Å; G150-L152 PolarHBondContact O-N 3.32Å; L152-R154 PolarHBondContact O-N 2.95Å; L152-L155 HydrophobicContact CB-CD1 4.41Å; L152-L155 HydrophobicContact CD2-CD1 3.82Å; L152-L155 HydrophobicContact CD2-CG 4.19Å; L152-L155 WeakPolarHBondContact O-CB 3.2Å; L152-L155 PolarHBondContact O-N 3.37Å; L152-F270 HydrophobicContact CD1-CD2 4.22Å; L152-F270 HydrophobicContact CD1-CE2 3.75Å
153R42.6Very low46.6Very low212 Ų212110.3 Ų110.380%0.854%0.537SS*.G310 helixtrans-53-21.4161.8-79.7-166178.7-161.61.6112.5L155 Q156R153-L155 VanDerWaalsContact C-N 3.26Å; R153-L155 PolarHBondContact O-N 2.8Å; R153-Q156 WeakPolarHBondContact O-CB 3.41Å; R153-Q156 WeakPolarHBondContact O-CG 3.29Å; R153-Q156 PolarHBondContact O-N 2.93Å; R153-Q156 VanDerWaalsContact O-N 3.13Å
154R40.3Very low45.3Very low229 Ų229106.3 Ų106.386%0.86453%0.53SS*.G310 helixtrans-72.2-7.1174.3-61.7-171.2-161.7-172.45.1115.2L152 Q156L152-R154 PolarHBondContact O-N 2.95Å; R154-Q156 PolarHBondContact O-N 2.91Å
155L41.1Very low43.9Very low82 Ų82103.8 Ų103.843%0.42952%0.521SS..G310 helixtrans-75.3-1.1164.9-73.2171.4000112.2L152 R153 E157L152-L155 HydrophobicContact CB-CD1 4.41Å; L152-L155 HydrophobicContact CD2-CD1 3.82Å; L152-L155 HydrophobicContact CD2-CG 4.19Å; L152-L155 WeakPolarHBondContact O-CB 3.2Å; L152-L155 PolarHBondContact O-N 3.37Å; R153-L155 VanDerWaalsContact C-N 3.26Å; R153-L155 PolarHBondContact O-N 2.8Å; L155-E157 PolarHBondContact O-N 2.87Å
156Q40.9Very low42.9Very low152 Ų152106.4 Ų106.471%0.7154%0.538SS*.SBendtrans-55.3108.8157.3-81.8-175.8-16.200108.2R153 R154R153-Q156 WeakPolarHBondContact O-CB 3.41Å; R153-Q156 WeakPolarHBondContact O-CG 3.29Å; R153-Q156 PolarHBondContact O-N 2.93Å; R153-Q156 VanDerWaalsContact O-N 3.13Å; R154-Q156 PolarHBondContact O-N 2.91Å
157E46.5Very low41.7Very low37 Ų37110.2 Ų110.217%0.17356%0.558CS.*  trans-42.7138.3179.7-63.6165.7138.300111.4L155 G159 R195 F279L155-E157 PolarHBondContact O-N 2.87Å; E157-G159 PolarHBondContact O-N 2.81Å; E157-R195 IonicContact OE2-CZ 3.93Å; E157-R195 IonicContact OE2-NH1 2.88Å; E157-R195 PolarHBondContact OE2-NH1 3.18Å; E157-R195 IonicContact OE2-NH2 3.23Å; E157-F279 VanDerWaalsContact OE1-CD1 3.23Å; E157-F279 WeakPolarHBondContact OE1-CD1 3.47Å; E157-F279 WeakPolarHBondContact OE1-CE1 3.23Å
158P35.3Very low40.4Very low128 Ų128106.8 Ų106.883%0.83154%0.542SS*.THydrogen-bonded Turntrans-60.9112.5167.99.2-5.1000109
159G37.6Very low38.8Very low47 Ų47107.7 Ų107.749%0.48555%0.553SS.*THydrogen-bonded Turntrans107.1-3162.200000118.4E157 Q161 Y798E157-G159 PolarHBondContact O-N 2.81Å; G159-Q161 VanDerWaalsContact C-N 3.32Å; G159-Q161 PolarHBondContact O-N 3.14Å; G159-Y798 PolarHBondContact O-OH 2.88Å
160F36.7Very low37.6Very low48 Ų48108.6 Ų108.621%0.21156%0.56CS.*  trans-80.676.8177.4-149.8-91.1000112V162 Y798 K799F160-V162 HydrophobicContact CD1-CG2 4.27Å; F160-V162 HydrophobicContact CE1-CG2 4.26Å; F160-V162 PolarHBondContact O-N 2.92Å; F160-Y798 HydrophobicContact CD2-CE1 4.36Å; F160-K799 HydrophobicContact CD2-CG 4.21Å; F160-K799 HydrophobicContact CE2-CG 4Å
161Q31Very low36.6Very low134 Ų134113 Ų11363%0.62657%0.574SS**  trans-78.7111.9161.9-74.7-172.6-9.700108.6G159 S163 A164G159-Q161 VanDerWaalsContact C-N 3.32Å; G159-Q161 PolarHBondContact O-N 3.14Å; Q161-S163 PolarHBondContact O-N 3.35Å; Q161-S163 VanDerWaalsContact O-N 3.08Å; Q161-A164 HydrophobicContact CB-CB 4.14Å; Q161-A164 PolarHBondContact O-N 3Å
162V35.3Very low36.1Very low102 Ų102105.8 Ų105.862%0.61856%0.563SS**G310 helixtrans-54.2-28.8174.2179.20000111.5F160 A164F160-V162 HydrophobicContact CD1-CG2 4.27Å; F160-V162 HydrophobicContact CE1-CG2 4.26Å; F160-V162 PolarHBondContact O-N 2.92Å; V162-A164 PolarHBondContact O-N 3.28Å
163S30.2Very low35.5Very low107 Ų107111.6 Ų111.675%0.74859%0.588SS**G310 helixtrans-70.7-10.2176.952.10000115.1Q161Q161-S163 PolarHBondContact O-N 3.35Å; Q161-S163 VanDerWaalsContact O-N 3.08Å
164A33.1Very low35.3Very low57 Ų57106.2 Ų106.247%0.47158%0.575SS.*G310 helixtrans-112.323.3-176.100000113.6Q161 V162 P166Q161-A164 HydrophobicContact CB-CB 4.14Å; Q161-A164 PolarHBondContact O-N 3Å; V162-A164 PolarHBondContact O-N 3.28Å; A164-P166 WeakPolarHBondContact O-CD 3.41Å
165L33.8Very low35.2Very low73 Ų73103.1 Ų103.138%0.38258%0.576SS.*SBendtrans-58.7121.2160.3-76.4166.5000107K167L165-K167 PolarHBondContact O-N 2.96Å
166P31.8Very low35.1Very low62 Ų62106.9 Ų106.940%0.40359%0.589SS.*  trans-57.7122.417420.4-27.5000107.3A164 V168 R199A164-P166 WeakPolarHBondContact O-CD 3.41Å; P166-V168 PolarHBondContact O-N 3.04Å; P166-R199 PolarHBondContact O-NH1 3.19Å
167K30.4Very low35.3Very low196 Ų196107.8 Ų107.885%0.85259%0.586SS**  trans-49.9114.2164.6-72.7-177.9177.1-177.60105.4L165 N169L165-K167 PolarHBondContact O-N 2.96Å; K167-N169 PolarHBondContact O-N 3.32Å
168V32.9Very low35.4Very low68 Ų68114.2 Ų114.241%0.41262%0.616SS.*  trans-62.4112.8168-173.60000104.6P166 I170P166-V168 PolarHBondContact O-N 3.04Å; V168-I170 HydrophobicContact CG1-CD1 4.45Å; V168-I170 HydrophobicContact CG1-CG1 3.84Å; V168-I170 PolarHBondContact O-N 2.61Å
169N27.8Very low36.2Very low146 Ų146110.5 Ų110.578%0.78159%0.592SS**  trans-70.673.6163.6-99.1-7.9000106.8K167K167-N169 PolarHBondContact O-N 3.32Å
170I34Very low37.4Very low69 Ų69111.9 Ų111.935%0.35459%0.593SS.*SBendtrans-76.5123.8141.5-63177.1000102.8V168 A172 P200V168-I170 HydrophobicContact CG1-CD1 4.45Å; V168-I170 HydrophobicContact CG1-CG1 3.84Å; V168-I170 PolarHBondContact O-N 2.61Å; I170-A172 PolarHBondContact O-N 2.9Å; I170-P200 HydrophobicContact CD1-CB 3.95Å; I170-P200 HydrophobicContact CD1-CG 3.39Å
171D32.9Very low39Very low134 Ų134111 Ų11172%0.71759%0.59SS**  trans-29.7105.7178.5-63.8-50.9000111.3E173D171-E173 PolarHBondContact O-N 3.28Å
172A35.2Very low41.2Very low74 Ų74107.4 Ų107.461%0.61258%0.579SS**THydrogen-bonded Turntrans-75.935.1-169.800000112.3I170 D174I170-A172 PolarHBondContact O-N 2.9Å; A172-D174 VanDerWaalsContact C-N 3.3Å
173E35.7Very low43.1Very low187 Ų187106.7 Ų106.787%0.87458%0.584SS**THydrogen-bonded Turntrans-81.6-11168.7-71.7-159.715700112.6D171D171-E173 PolarHBondContact O-N 3.28Å
174D38.2Very low45.4Very low98 Ų98104.2 Ų104.252%0.52457%0.567SS.*  trans-134.199.9167.7-97-40.9000110.8A172 K176A172-D174 VanDerWaalsContact C-N 3.3Å; D174-K176 HydrophobicContact CB-CB 4.25Å; D174-K176 PolarHBondContact O-N 2.79Å; D174-K176 IonicContact OD1-NZ 3.4Å
175N38.8Very low47.7Very low165 Ų165104.2 Ų104.288%0.88256%0.557SS**THydrogen-bonded Turntrans-60.630.6162.6-87.5-29.5000113
176K38.8Very low49.9Very low160 Ų160102.9 Ų102.970%0.69655%0.554SS**THydrogen-bonded Turntrans-101.4-3.7-172.7-81.8-178179.4162.60115.7D174 Q178D174-K176 HydrophobicContact CB-CB 4.25Å; D174-K176 PolarHBondContact O-N 2.79Å; D174-K176 IonicContact OD1-NZ 3.4Å; K176-Q178 PolarHBondContact O-N 2.79Å
177W45.4Very low52.3Low172 Ų172106.4 Ų106.465%0.65257%0.565SS**  trans-90.689.6179.3-70.398.6000111.8V211W177-V211 HydrophobicContact CH2-CB 4.49Å; W177-V211 HydrophobicContact CH2-CG2 3.93Å; W177-V211 HydrophobicContact CZ2-CG2 4.25Å; W177-V211 HydrophobicContact CZ3-CG2 4.49Å
178Q47.7Very low55Low172 Ų17298 Ų9880%0.80453%0.528SS*.  trans-83.8149.9163.3-67.2180-3.700109.5K176K176-Q178 PolarHBondContact O-N 2.79Å
179C53.2Low57.4Low50 Ų5095 Ų9534%0.33851%0.511SS..  trans-47.8130171.8178.50000109.7M181 H215C179-M181 PolarHBondContact O-N 3.26Å; C179-M181 VanDerWaalsContact SG-CE 3.52Å; C179-H215 PolarHBondContact SG-NE2 2.99Å
180P62.6Low60Low76 Ų7692.8 Ų92.849%0.49450%0.499SS..SBendtrans-76.850.1-178.933.6-36.4000110.9C213P180-C213 HydrophobicContact CG-CB 4.35Å
181M70.3Confident62.3Low30 Ų3091 Ų9115%0.14849%0.49CS..  trans-107.4132.2168.4-75-168.1-58.700108.5C179 E185 L196 M554C179-M181 PolarHBondContact O-N 3.26Å; C179-M181 VanDerWaalsContact SG-CE 3.52Å; M181-E185 HydrophobicContact CB-CB 4.06Å; M181-E185 HydrophobicContact CG-CB 4.23Å; M181-E185 HydrophobicContact SD-CB 4.47Å; M181-L196 HydrophobicContact CE-CD2 3.35Å; M181-M554 HydrophobicContact SD-CE 4.46Å
182S76.2Confident64.7Low58 Ų5885.3 Ų85.341%0.40646%0.459SS..  trans-58.1160.716264.70000110.7S184 E185 S186S182-S184 PolarHBondContact O-N 3.22Å; S182-E185 WeakPolarHBondContact CB-OE2 3.25Å; S182-E185 PolarHBondContact N-OE2 3.42Å; S182-E185 PolarHBondContact O-N 3.17Å; S182-E185 WeakPolarHBondContact OG-CB 3.49Å; S182-E185 VanDerWaalsContact OG-CG 3.22Å; S182-E185 WeakPolarHBondContact OG-CG 3.36Å; S182-E185 PolarHBondContact OG-N 2.74Å; S182-E185 PolarHBondContact OG-OE2 2.93Å; S182-S186 PolarHBondContact O-N 2.82Å
183A75.4Confident67Low86 Ų8682.4 Ų82.471%0.71143%0.433SS*.Hα-helixtrans-57.2-40177.100000112.1S186 E187A183-S186 PolarHBondContact O-N 3.46Å; A183-E187 PolarHBondContact O-N 3.37Å
184S79.8Confident69.2Low56 Ų5674.2 Ų74.239%0.39240%0.397SS..Hα-helixtrans-65.2-46.1176.5166.90000112S182 S186 E187 H188S182-S184 PolarHBondContact O-N 3.22Å; S184-S186 VanDerWaalsContact C-N 3.27Å; S184-S186 PolarHBondContact O-N 3.12Å; S184-E187 WeakPolarHBondContact O-CB 3.48Å; S184-E187 PolarHBondContact O-N 2.97Å; S184-E187 VanDerWaalsContact O-N 3.14Å; S184-H188 PolarHBondContact O-N 3.1Å
185E80.5Confident70.9Confident57 Ų5772 Ų7227%0.26638%0.381SS..Hα-helixtrans-61.9-36.6175.8-74168.6120.300112.1M181 S182 H188 S189 M554M181-E185 HydrophobicContact CB-CB 4.06Å; M181-E185 HydrophobicContact CG-CB 4.23Å; M181-E185 HydrophobicContact SD-CB 4.47Å; S182-E185 WeakPolarHBondContact CB-OE2 3.25Å; S182-E185 PolarHBondContact N-OE2 3.42Å; S182-E185 PolarHBondContact O-N 3.17Å; S182-E185 WeakPolarHBondContact OG-CB 3.49Å; S182-E185 VanDerWaalsContact OG-CG 3.22Å; S182-E185 WeakPolarHBondContact OG-CG 3.36Å; S182-E185 PolarHBondContact OG-N 2.74Å; S182-E185 PolarHBondContact OG-OE2 2.93Å; E185-H188 PolarHBondContact O-N 3.18Å; E185-S189 WeakPolarHBondContact O-CB 3.23Å; E185-S189 PolarHBondContact O-N 3.08Å; E185-M554 HydrophobicContact CB-CE 4.27Å
186S80.3Confident73Confident45 Ų4567.2 Ų67.232%0.31536%0.355SS..Hα-helixtrans-64.6-41.8175.1-170.60000111.5S182 A183 S184 S189 N190S182-S186 PolarHBondContact O-N 2.82Å; A183-S186 PolarHBondContact O-N 3.46Å; S184-S186 VanDerWaalsContact C-N 3.27Å; S184-S186 PolarHBondContact O-N 3.12Å; S186-S189 PolarHBondContact O-N 2.97Å; S186-N190 WeakPolarHBondContact O-CB 3.1Å; S186-N190 PolarHBondContact O-N 2.75Å; S186-N190 PolarHBondContact O-ND2 3.21Å
187E82.4Confident75.1Confident136 Ų13659.9 Ų59.964%0.63632%0.324SS*.Hα-helixtrans-62.5-48.3175.1-174.5170.9-168.100111.7A183 S184 S189 N190 L191A183-E187 PolarHBondContact O-N 3.37Å; S184-E187 WeakPolarHBondContact O-CB 3.48Å; S184-E187 PolarHBondContact O-N 2.97Å; S184-E187 VanDerWaalsContact O-N 3.14Å; E187-S189 VanDerWaalsContact C-N 3.35Å; E187-S189 PolarHBondContact O-N 3.38Å; E187-N190 PolarHBondContact O-N 3.34Å; E187-L191 PolarHBondContact O-N 2.93Å
188H86.5Confident76.9Confident18 Ų1853.8 Ų53.88%0.08331%0.307CS..Hα-helixtrans-60.7-44.1175.9-67.6179.2000111.9S184 E185 N190 L191 L192 W553 M554 E638S184-H188 PolarHBondContact O-N 3.1Å; E185-H188 PolarHBondContact O-N 3.18Å; H188-N190 VanDerWaalsContact C-N 3.32Å; H188-N190 PolarHBondContact O-N 3.19Å; H188-L191 WeakPolarHBondContact O-CB 3.46Å; H188-L191 PolarHBondContact O-N 3.47Å; H188-L191 VanDerWaalsContact O-N 3.13Å; H188-L192 PolarHBondContact O-N 3.41Å; H188-W553 HydrophobicContact CB-CE3 4.04Å; H188-W553 AromaticContact CD2-CE3 3.74Å; H188-W553 AromaticContact CD2-CZ3 3.85Å; H188-W553 AromaticContact CG-CE3 3.72Å; H188-W553 PolarHBondContact ND1-O 3.36Å; H188-W553 VanDerWaalsContact ND1-O 3.08Å; H188-M554 HydrophobicContact CB-SD 3.58Å; H188-M554 VanDerWaalsContact CB-SD 3.58Å; H188-E638 IonicContact CE1-OE1 2.91Å; H188-E638 PolarHBondContact CE1-OE1 3.25Å; H188-E638 IonicContact NE2-OE1 3.59Å; H188-E638 PolarHBondContact NE2-OE1 2.93Å
189S84.3Confident78.8Confident6 Ų646.4 Ų46.44%0.04227%0.272CS..Hα-helixtrans-61.1-41.8176.8-179.20000111.4E185 S186 E187 L191 L192 F193E185-S189 WeakPolarHBondContact O-CB 3.23Å; E185-S189 PolarHBondContact O-N 3.08Å; S186-S189 PolarHBondContact O-N 2.97Å; E187-S189 VanDerWaalsContact C-N 3.35Å; E187-S189 PolarHBondContact O-N 3.38Å; S189-L191 VanDerWaalsContact C-N 3.27Å; S189-L191 PolarHBondContact O-N 3.03Å; S189-L192 PolarHBondContact O-N 2.77Å; S189-F193 WeakPolarHBondContact O-CA 3.43Å; S189-F193 WeakPolarHBondContact O-CB 3.48Å; S189-F193 PolarHBondContact O-N 2.95Å
190N81.5Confident80.5Confident99 Ų9945.6 Ų45.653%0.52927%0.266SS..Hα-helixtrans-71.1-24.9177.9-73.6-35.3000112.5S186 E187 H188 K220S186-N190 WeakPolarHBondContact O-CB 3.1Å; S186-N190 PolarHBondContact O-N 2.75Å; S186-N190 PolarHBondContact O-ND2 3.21Å; E187-N190 PolarHBondContact O-N 3.34Å; H188-N190 VanDerWaalsContact C-N 3.32Å; H188-N190 PolarHBondContact O-N 3.19Å; N190-K220 WeakPolarHBondContact O-CE 3.45Å; N190-K220 PolarHBondContact O-NZ 3.48Å
191L82.2Confident81.7Confident33 Ų3342.9 Ų42.917%0.17325%0.246CC..Hα-helixtrans-72.9-45.8173.8-173.664.4000111.3E187 H188 S189 K220 W553 M611 K616 C618E187-L191 PolarHBondContact O-N 2.93Å; H188-L191 WeakPolarHBondContact O-CB 3.46Å; H188-L191 PolarHBondContact O-N 3.47Å; H188-L191 VanDerWaalsContact O-N 3.13Å; S189-L191 VanDerWaalsContact C-N 3.27Å; S189-L191 PolarHBondContact O-N 3.03Å; L191-K220 VanDerWaalsContact O-CD 3.29Å; L191-K220 WeakPolarHBondContact O-CD 3.42Å; L191-K220 VanDerWaalsContact O-CE 3.3Å; L191-K220 WeakPolarHBondContact O-CE 3.31Å; L191-K220 PolarHBondContact O-NZ 3.32Å; L191-W553 HydrophobicContact CD2-CE3 4.09Å; L191-W553 HydrophobicContact CD2-CH2 3.41Å; L191-W553 VanDerWaalsContact CD2-CH2 3.41Å; L191-W553 HydrophobicContact CD2-CZ2 4.23Å; L191-W553 HydrophobicContact CD2-CZ3 3.33Å; L191-M611 HydrophobicContact CD2-CE 4.25Å; L191-K616 WeakPolarHBondContact CD1-O 2.89Å; L191-C618 HydrophobicContact CD1-CB 4.45Å; L191-C618 HydrophobicContact CD2-CB 3.6Å; L191-C618 HydrophobicContact CG-CB 3.77Å
192L83.7Confident82.6Confident13 Ų1348 Ų487%0.06827%0.268CS..Hα-helixtrans-86.5-35.8-174.7-68.8-173.9000114.7H188 S189 K220 L549 W553 M554 C618H188-L192 PolarHBondContact O-N 3.41Å; S189-L192 PolarHBondContact O-N 2.77Å; L192-K220 WeakPolarHBondContact O-CB 3.14Å; L192-K220 WeakPolarHBondContact O-CG 3.43Å; L192-K220 PolarHBondContact O-N 3.49Å; L192-L549 HydrophobicContact CD1-CB 4.35Å; L192-L549 HydrophobicContact CD2-CB 4.09Å; L192-L549 HydrophobicContact CD2-CD1 4.23Å; L192-W553 HydrophobicContact CD1-CB 3.44Å; L192-W553 VanDerWaalsContact CD1-CB 3.44Å; L192-W553 HydrophobicContact CD1-CD2 4.37Å; L192-W553 HydrophobicContact CD1-CG 3.7Å; L192-W553 HydrophobicContact CD2-CD2 4.47Å; L192-W553 HydrophobicContact CD2-CG 4.39Å; L192-W553 HydrophobicContact CG-CB 4.38Å; L192-W553 HydrophobicContact CG-CD2 4.48Å; L192-W553 HydrophobicContact CG-CG 4.28Å; L192-M554 HydrophobicContact CD1-CG 4.21Å; L192-C618 HydrophobicContact CD2-CB 3.92Å; L192-C618 WeakPolarHBondContact CD2-SG 3.45Å
193F84.6Confident83.3Confident13 Ų1345.4 Ų45.46%0.05725%0.249CC..EExtended strand (participates in β ladder)trans-124161.8-169.6-47-72.2000112S189 A217 E218 P219 V299 N550 M554S189-F193 WeakPolarHBondContact O-CA 3.43Å; S189-F193 WeakPolarHBondContact O-CB 3.48Å; S189-F193 PolarHBondContact O-N 2.95Å; F193-A217 HydrophobicContact CB-CB 3.61Å; F193-A217 HydrophobicContact CG-CB 4.1Å; F193-E218 CarbonylContact C-O 3.52Å; F193-E218 WeakPolarHBondContact CA-O 3.34Å; F193-P219 HydrophobicContact CD1-CB 4.2Å; F193-P219 HydrophobicContact CD1-CG 4.09Å; F193-P219 HydrophobicContact CE1-CB 4.35Å; F193-P219 HydrophobicContact CE1-CG 4.14Å; F193-V299 HydrophobicContact CD1-CB 4.47Å; F193-V299 HydrophobicContact CD1-CG1 3.57Å; F193-V299 HydrophobicContact CD2-CG1 4.47Å; F193-V299 HydrophobicContact CE1-CB 4.08Å; F193-V299 HydrophobicContact CE1-CG1 3.58Å; F193-V299 HydrophobicContact CE2-CG1 4.45Å; F193-V299 HydrophobicContact CG-CG1 4.08Å; F193-V299 HydrophobicContact CZ-CG1 4.04Å; F193-N550 HydrophobicContact CZ-CB 4.03Å; F193-N550 WeakPolarHBondContact CZ-OD1 3.33Å; F193-M554 HydrophobicContact CE2-CG 3.93Å
194A80.1Confident84Confident15 Ų1542.4 Ų42.412%0.12422%0.223CC..EExtended strand (participates in β ladder)trans-124.1158.6172.100000110.5L196 E218 Y277A194-L196 PolarHBondContact O-N 3.22Å; A194-E218 PolarHBondContact N-O 2.92Å; A194-E218 PolarHBondContact O-N 3.47Å; A194-Y277 HydrophobicContact CB-CD1 3.9Å; A194-Y277 HydrophobicContact CB-CE1 4.34Å
195R75.6Confident84.5Confident52 Ų5245.2 Ų45.220%0.19623%0.229CC..EExtended strand (participates in β ladder)trans51.852.1171.2-61.9-179.1169.8-168.2-8.3113.7E157 I197 E218 Y277E157-R195 IonicContact OE2-CZ 3.93Å; E157-R195 IonicContact OE2-NH1 2.88Å; E157-R195 PolarHBondContact OE2-NH1 3.18Å; E157-R195 IonicContact OE2-NH2 3.23Å; R195-I197 PolarHBondContact O-N 3.1Å; R195-E218 WeakPolarHBondContact CD-OE1 3.1Å; R195-E218 WeakPolarHBondContact CD-OE2 3.36Å; R195-Y277 HydrophobicContact CG-CD1 3.66Å; R195-Y277 HydrophobicContact CG-CE1 3.74Å; R195-Y277 HydrophobicContact CG-CG 4.25Å; R195-Y277 VanDerWaalsContact CZ-CD2 3.49Å
196L81.4Confident84.7Confident64 Ų6443.6 Ų43.634%0.33522%0.224SC..EExtended strand (participates in β ladder)trans-59.8124.8172.8-178.867.4000110.5M181 A194 H215 M216 A217M181-L196 HydrophobicContact CE-CD2 3.35Å; A194-L196 PolarHBondContact O-N 3.22Å; L196-H215 HydrophobicContact CD1-CB 3.97Å; L196-M216 CarbonylContact C-O 3.55Å; L196-M216 WeakPolarHBondContact CA-O 3.45Å; L196-A217 HydrophobicContact CB-CB 4.46Å; L196-A217 HydrophobicContact CD1-CB 4.01Å
197I83.1Confident84.7Confident7 Ų749.2 Ų49.24%0.03625%0.25CS..EExtended strand (participates in β ladder)trans-113.5137.1171.7-62.4165000106.9R195 H215 M216 T792 E795R195-I197 PolarHBondContact O-N 3.1Å; I197-H215 CarbonylContact O-C 3.58Å; I197-H215 VanDerWaalsContact O-CA 3.25Å; I197-H215 WeakPolarHBondContact O-CA 3.33Å; I197-M216 HydrophobicContact CD1-CE 3.82Å; I197-M216 PolarHBondContact N-O 3.29Å; I197-M216 PolarHBondContact O-N 3.34Å; I197-T792 HydrophobicContact CG2-CG2 4.16Å; I197-E795 HydrophobicContact CD1-CB 3.87Å; I197-E795 HydrophobicContact CD1-CG 4.26Å; I197-E795 HydrophobicContact CG2-CG 4.24Å
198C84.4Confident84.6Confident44 Ų4447.7 Ų47.730%0.29725%0.252SS..EExtended strand (participates in β ladder)trans-127133178.2-175.60000110.1E214C198-E214 CarbonylContact C-O 3.56Å; C198-E214 VanDerWaalsContact CA-O 3.3Å; C198-E214 WeakPolarHBondContact CA-O 3.27Å
199R87.8Confident84.5Confident17 Ų1751.3 Ų51.36%0.06428%0.276CS..EExtended strand (participates in β ladder)trans-129.7110.2175.6-66.6-65.1-171.8-158.80.4109.7P166 F201 E214 E790 T792 E795P166-R199 PolarHBondContact O-NH1 3.19Å; R199-F201 HydrophobicContact CB-CE2 3.59Å; R199-F201 HydrophobicContact CB-CZ 3.92Å; R199-F201 WeakPolarHBondContact O-CD2 3.35Å; R199-F201 WeakPolarHBondContact O-CE2 3.1Å; R199-E214 HydrophobicContact CB-CB 4.48Å; R199-E214 PolarHBondContact N-O 2.96Å; R199-E214 PolarHBondContact O-N 3.34Å; R199-E790 VanDerWaalsContact CD-O 3.3Å; R199-E790 WeakPolarHBondContact CD-O 3.35Å; R199-E790 WeakPolarHBondContact CG-O 3.29Å; R199-E790 PolarHBondContact NE-O 2.96Å; R199-T792 HydrophobicContact CB-CG2 4.12Å; R199-T792 HydrophobicContact CG-CG2 3.84Å; R199-E795 IonicContact CZ-OE1 2.9Å; R199-E795 IonicContact NH2-OE1 3.84Å; R199-E795 PolarHBondContact NH2-OE1 2.84Å
200P87.5Confident84.6Confident32 Ų3251.7 Ų51.721%0.20828%0.278CS..EExtended strand (participates in β ladder)trans-83.9143.3174.330.5-33.5000112.5I170 V211 L212I170-P200 HydrophobicContact CD1-CB 3.95Å; I170-P200 HydrophobicContact CD1-CG 3.39Å; P200-V211 HydrophobicContact CB-CG1 4.36Å; P200-L212 CarbonylContact C-O 3.46Å; P200-L212 WeakPolarHBondContact CA-O 3.41Å
201F89.1Confident84.8Confident19 Ų1948 Ų488%0.08326%0.259CS..EExtended strand (participates in β ladder)trans-135.8146.5178.2-60.2-86.8000110.4R199 V211 L212 E214 D786 L787 E790R199-F201 HydrophobicContact CB-CE2 3.59Å; R199-F201 HydrophobicContact CB-CZ 3.92Å; R199-F201 WeakPolarHBondContact O-CD2 3.35Å; R199-F201 WeakPolarHBondContact O-CE2 3.1Å; F201-V211 WeakPolarHBondContact O-CA 3.44Å; F201-L212 HydrophobicContact CB-CB 4.26Å; F201-L212 PolarHBondContact N-O 2.92Å; F201-L212 PolarHBondContact O-N 3.11Å; F201-E214 HydrophobicContact CE2-CB 4.15Å; F201-D786 HydrophobicContact CD1-CB 3.91Å; F201-D786 HydrophobicContact CE1-CB 4.09Å; F201-D786 WeakPolarHBondContact CE1-O 3.22Å; F201-L787 HydrophobicContact CD2-CD2 3.89Å; F201-L787 HydrophobicContact CE2-CD2 3.79Å; F201-L787 HydrophobicContact CG-CD2 4.42Å; F201-L787 HydrophobicContact CZ-CD2 4.22Å; F201-E790 HydrophobicContact CE1-CB 4Å; F201-E790 HydrophobicContact CZ-CB 4.35Å
202K89.2Confident85.1Confident138 Ų13846.4 Ų46.460%0.625%0.25SS*.EExtended strand (participates in β ladder)trans-80.9130.9167.6-68.5179.4-178.51730108.3P204 T209K202-P204 WeakPolarHBondContact O-CD 3.45Å; K202-T209 HydrophobicContact CG-CG2 4.36Å
203V89.5Confident85.3Confident4 Ų446.3 Ų46.32%0.02425%0.251CS..PPolyproline II helixtrans-77.1121.5173-1770000108.4T206 V210 L212 V769 Y773 L775V203-T206 HydrophobicContact CB-CG2 4Å; V203-T206 HydrophobicContact CG1-CG2 3.6Å; V203-T206 PolarHBondContact O-OG1 2.93Å; V203-V210 HydrophobicContact CB-CB 4.03Å; V203-V210 HydrophobicContact CB-CG1 4.2Å; V203-V210 HydrophobicContact CG2-CB 4.05Å; V203-V210 HydrophobicContact CG2-CG1 3.67Å; V203-V210 PolarHBondContact N-O 3.4Å; V203-L212 HydrophobicContact CG2-CB 3.83Å; V203-V769 HydrophobicContact CG1-CG1 3.57Å; V203-V769 HydrophobicContact CG2-CG1 4.12Å; V203-Y773 HydrophobicContact CG1-CD2 3.93Å; V203-Y773 HydrophobicContact CG1-CE2 4.42Å; V203-Y773 HydrophobicContact CG1-CG 4.45Å; V203-Y773 HydrophobicContact CG2-CE2 4.49Å; V203-L775 HydrophobicContact CG1-CD1 4.02Å; V203-L775 HydrophobicContact CG1-CD2 4.05Å
204P90.7Very high85.5Confident23 Ų2345.7 Ų45.715%0.14925%0.248CC..THydrogen-bonded Turntrans-58.2155.5178.3-25.937.3000112.1K202 T206 L775 G779 I782 L783K202-P204 WeakPolarHBondContact O-CD 3.45Å; P204-T206 PolarHBondContact O-N 3Å; P204-L775 WeakPolarHBondContact O-CD2 3.32Å; P204-G779 WeakPolarHBondContact CG-O 3.1Å; P204-I782 HydrophobicContact CG-CB 4.38Å; P204-I782 HydrophobicContact CG-CG2 4.13Å; P204-L783 HydrophobicContact CG-CB 4.18Å
205E90.8Very high85.9Confident114 Ų11445.2 Ų45.253%0.53324%0.243SC..THydrogen-bonded Turntrans59.615.4168.7-54.8171.4178.700116.1L775 S776 G779E205-L775 HydrophobicContact CB-CD2 4.27Å; E205-S776 VanDerWaalsContact CD-OG 3.26Å; E205-S776 WeakPolarHBondContact OE1-CB 3.49Å; E205-S776 PolarHBondContact OE1-OG 3.27Å; E205-S776 WeakPolarHBondContact OE2-CB 3.46Å; E205-S776 PolarHBondContact OE2-N 2.97Å; E205-S776 PolarHBondContact OE2-OG 3.08Å; E205-G779 WeakPolarHBondContact OE1-CA 3.37Å; E205-G779 PolarHBondContact OE1-N 3.32Å
206T84.7Confident86.5Confident23 Ų2342.8 Ų42.814%0.14123%0.234CC..  trans-97.8136.8177.255.60000111.9V203 P204 P208 V210 Y773 L775V203-T206 HydrophobicContact CB-CG2 4Å; V203-T206 HydrophobicContact CG1-CG2 3.6Å; V203-T206 PolarHBondContact O-OG1 2.93Å; P204-T206 PolarHBondContact O-N 3Å; T206-P208 CarbonylContact C-O 3.57Å; T206-V210 HydrophobicContact CG2-CB 4.1Å; T206-V210 HydrophobicContact CG2-CG2 4.01Å; T206-V210 PolarHBondContact OG1-N 3.33Å; T206-Y773 HydrophobicContact CG2-CD1 4.02Å; T206-Y773 HydrophobicContact CG2-CD2 4.49Å; T206-Y773 HydrophobicContact CG2-CG 3.87Å; T206-L775 HydrophobicContact CG2-CD2 4.37Å
207N80.6Confident86.7Confident163 Ų16339.8 Ų39.887%0.87222%0.219SC*.SBendtrans-137.3114.6171-171.95.8000109.9
208P80.7Confident86.6Confident105 Ų10539.5 Ų39.568%0.68222%0.217SC*.SBendcis-65160.10.229.8-35.8000112.5T206 V210T206-P208 CarbonylContact C-O 3.57Å; P208-V210 PolarHBondContact O-N 3.45Å; P208-V210 VanDerWaalsContact O-N 3.1Å
209T83.6Confident86.3Confident94 Ų9437.6 Ų37.658%0.57720%0.204SC*.  trans-57.4115.3179.3-51.50000110.5K202K202-T209 HydrophobicContact CG-CG2 4.36Å
210V85.4Confident85.6Confident14 Ų1441.1 Ų41.19%0.08522%0.22CC..  trans-86.2140.1173.6172.30000109.3V203 T206 P208 C304 Y773V203-V210 HydrophobicContact CB-CB 4.03Å; V203-V210 HydrophobicContact CB-CG1 4.2Å; V203-V210 HydrophobicContact CG2-CB 4.05Å; V203-V210 HydrophobicContact CG2-CG1 3.67Å; V203-V210 PolarHBondContact N-O 3.4Å; T206-V210 HydrophobicContact CG2-CB 4.1Å; T206-V210 HydrophobicContact CG2-CG2 4.01Å; T206-V210 PolarHBondContact OG1-N 3.33Å; P208-V210 PolarHBondContact O-N 3.45Å; P208-V210 VanDerWaalsContact O-N 3.1Å; V210-C304 HydrophobicContact CG1-CB 4.46Å; V210-Y773 HydrophobicContact CB-CE1 4.37Å; V210-Y773 HydrophobicContact CG1-CE1 4.05Å; V210-Y773 HydrophobicContact CG1-CE2 3.95Å; V210-Y773 VanDerWaalsContact CG1-OH 3.23Å; V210-Y773 WeakPolarHBondContact CG1-OH 3.29Å; V210-Y773 HydrophobicContact CG2-CD1 4.26Å; V210-Y773 HydrophobicContact CG2-CE1 3.72Å
211V86Confident84.5Confident21 Ų2141.2 Ų41.213%0.12722%0.219CC..EExtended strand (participates in β ladder)trans-106.9132.3173-179.60000109.6W177 P200 F201 S305W177-V211 HydrophobicContact CH2-CB 4.49Å; W177-V211 HydrophobicContact CH2-CG2 3.93Å; W177-V211 HydrophobicContact CZ2-CG2 4.25Å; W177-V211 HydrophobicContact CZ3-CG2 4.49Å; P200-V211 HydrophobicContact CB-CG1 4.36Å; F201-V211 WeakPolarHBondContact O-CA 3.44Å; V211-S305 PolarHBondContact N-OG 3.33Å; V211-S305 PolarHBondContact O-N 3.42Å
212L88.9Confident83.1Confident0 Ų041.2 Ų41.20%022%0.219CC..EExtended strand (participates in β ladder)trans-103.2124.8174.4-170.476.6000109.4P200 F201 V203 V302 R303 C304 V769 L783 L787P200-L212 CarbonylContact C-O 3.46Å; P200-L212 WeakPolarHBondContact CA-O 3.41Å; F201-L212 HydrophobicContact CB-CB 4.26Å; F201-L212 PolarHBondContact N-O 2.92Å; F201-L212 PolarHBondContact O-N 3.11Å; V203-L212 HydrophobicContact CG2-CB 3.83Å; L212-V302 HydrophobicContact CD1-CG1 3.16Å; L212-V302 HydrophobicContact CD2-CG1 4.14Å; L212-V302 HydrophobicContact CG-CG1 3.7Å; L212-R303 CarbonylContact C-O 3.6Å; L212-C304 VanDerWaalsContact CD1-SG 3.54Å; L212-V769 HydrophobicContact CD1-CG2 3.59Å; L212-V769 HydrophobicContact CD2-CG2 4.08Å; L212-V769 HydrophobicContact CG-CG2 4.49Å; L212-L783 HydrophobicContact CD2-CD1 4Å; L212-L787 HydrophobicContact CD2-CD2 4.13Å
213C88Confident81.7Confident11 Ų1137.7 Ų37.77%0.07421%0.207CC..EExtended strand (participates in β ladder)trans-111.4110175.7-68.90000110.2P180 H215 V302 R303P180-C213 HydrophobicContact CG-CB 4.35Å; C213-H215 PolarHBondContact O-ND1 2.68Å; C213-V302 WeakPolarHBondContact O-CA 3.22Å; C213-R303 PolarHBondContact N-O 3.01Å; C213-R303 PolarHBondContact O-N 3.43Å
214E88.8Confident80.1Confident0 Ų038.1 Ų38.10%021%0.21CC..EExtended strand (participates in β ladder)trans-85.7126.1171.2-167.5-164.7174.300109.5C198 R199 F201 S301 V302 G791 T792C198-E214 CarbonylContact C-O 3.56Å; C198-E214 VanDerWaalsContact CA-O 3.3Å; C198-E214 WeakPolarHBondContact CA-O 3.27Å; R199-E214 HydrophobicContact CB-CB 4.48Å; R199-E214 PolarHBondContact N-O 2.96Å; R199-E214 PolarHBondContact O-N 3.34Å; F201-E214 HydrophobicContact CE2-CB 4.15Å; E214-S301 CarbonylContact C-O 3.55Å; E214-V302 HydrophobicContact CG-CG2 4.23Å; E214-G791 WeakPolarHBondContact OE2-CA 3.22Å; E214-T792 HydrophobicContact CB-CG2 4.05Å; E214-T792 HydrophobicContact CG-CG2 3.7Å; E214-T792 WeakPolarHBondContact O-CG2 3.26Å; E214-T792 WeakPolarHBondContact OE1-CB 3.22Å; E214-T792 PolarHBondContact OE1-N 2.92Å; E214-T792 PolarHBondContact OE1-OG1 2.79Å; E214-T792 PolarHBondContact OE2-N 2.92Å
215H88.3Confident78.4Confident5 Ų538.9 Ų38.92%0.02322%0.215CC..EExtended strand (participates in β ladder)trans-115.4143.1175.5-56.780.9000109.6C179 L196 I197 C213 Q300 S301C179-H215 PolarHBondContact SG-NE2 2.99Å; L196-H215 HydrophobicContact CD1-CB 3.97Å; I197-H215 CarbonylContact O-C 3.58Å; I197-H215 VanDerWaalsContact O-CA 3.25Å; I197-H215 WeakPolarHBondContact O-CA 3.33Å; C213-H215 PolarHBondContact O-ND1 2.68Å; H215-Q300 CarbonylContact O-C 3.59Å; H215-Q300 VanDerWaalsContact O-CA 3.24Å; H215-Q300 WeakPolarHBondContact O-CA 3.29Å; H215-S301 PolarHBondContact N-O 2.91Å; H215-S301 PolarHBondContact ND1-O 3.37Å; H215-S301 PolarHBondContact O-N 2.92Å
216M88.7Confident76.7Confident0 Ų036.1 Ų36.10%021%0.211CC..EExtended strand (participates in β ladder)trans-136.9131.2168.5178.517573.400110L196 I197 H298 V299 Q300 T792 E795 N796L196-M216 CarbonylContact C-O 3.55Å; L196-M216 WeakPolarHBondContact CA-O 3.45Å; I197-M216 HydrophobicContact CD1-CE 3.82Å; I197-M216 PolarHBondContact N-O 3.29Å; I197-M216 PolarHBondContact O-N 3.34Å; M216-H298 HydrophobicContact CG-CB 4.2Å; M216-H298 HydrophobicContact SD-CB 4.5Å; M216-V299 VanDerWaalsContact CA-O 3.29Å; M216-V299 WeakPolarHBondContact CA-O 3.39Å; M216-Q300 HydrophobicContact CB-CG 4.33Å; M216-Q300 HydrophobicContact CG-CG 4.23Å; M216-Q300 VanDerWaalsContact CG-NE2 3.32Å; M216-Q300 PolarHBondContact SD-NE2 2.88Å; M216-T792 HydrophobicContact CB-CG2 4.08Å; M216-T792 WeakPolarHBondContact CB-OG1 3.18Å; M216-T792 VanDerWaalsContact CE-O 3.23Å; M216-T792 WeakPolarHBondContact CE-O 3.5Å; M216-E795 HydrophobicContact CE-CB 4.22Å; M216-N796 HydrophobicContact CE-CB 4.16Å; M216-N796 HydrophobicContact SD-CB 4.16Å
217A85.1Confident75.7Confident2 Ų240.9 Ų40.92%0.01723%0.23CC..EExtended strand (participates in β ladder)trans-140.3165.4176.800000111.4F193 L196 H298 V299F193-A217 HydrophobicContact CB-CB 3.61Å; F193-A217 HydrophobicContact CG-CB 4.1Å; L196-A217 HydrophobicContact CB-CB 4.46Å; L196-A217 HydrophobicContact CD1-CB 4.01Å; A217-H298 CarbonylContact O-C 3.6Å; A217-H298 VanDerWaalsContact O-CA 3.25Å; A217-H298 WeakPolarHBondContact O-CA 3.23Å; A217-V299 HydrophobicContact CB-CG1 3.82Å; A217-V299 PolarHBondContact N-O 3.21Å; A217-V299 PolarHBondContact O-N 2.87Å
218E81.2Confident75.3Confident0 Ų034.6 Ų34.60%019%0.194CC..EExtended strand (participates in β ladder)trans-103.9118.7179.4-68.3158.2-155.900109.2F193 A194 R195 K220 F279 K799F193-E218 CarbonylContact C-O 3.52Å; F193-E218 WeakPolarHBondContact CA-O 3.34Å; A194-E218 PolarHBondContact N-O 2.92Å; A194-E218 PolarHBondContact O-N 3.47Å; R195-E218 WeakPolarHBondContact CD-OE1 3.1Å; R195-E218 WeakPolarHBondContact CD-OE2 3.36Å; E218-K220 PolarHBondContact O-N 3.39Å; E218-F279 HydrophobicContact CG-CD2 4.12Å; E218-K799 IonicContact OE1-NZ 2.78Å; E218-K799 PolarHBondContact OE1-NZ 3.48Å
219P77.9Confident75.5Confident4 Ų430.2 Ų30.23%0.02616%0.164CC..EExtended strand (participates in β ladder)trans-58.3138172.9-24.435.6000112F193 L221 L297 F313 S546F193-P219 HydrophobicContact CD1-CB 4.2Å; F193-P219 HydrophobicContact CD1-CG 4.09Å; F193-P219 HydrophobicContact CE1-CB 4.35Å; F193-P219 HydrophobicContact CE1-CG 4.14Å; P219-L221 PolarHBondContact O-N 3.39Å; P219-L297 HydrophobicContact CB-CD2 4.05Å; P219-L297 HydrophobicContact CG-CD2 3.92Å; P219-L297 HydrophobicContact CG-CG 3.89Å; P219-F313 HydrophobicContact CG-CE1 4.18Å; P219-S546 WeakPolarHBondContact CB-OG 3.24Å
220K72Confident75.7Confident91 Ų9128 Ų2840%0.39615%0.153SC..PPolyproline II helixtrans-68.4130.2170.2-67.6-174.6-165.6163.40109.5N190 L191 L192 E218 P278N190-K220 WeakPolarHBondContact O-CE 3.45Å; N190-K220 PolarHBondContact O-NZ 3.48Å; L191-K220 VanDerWaalsContact O-CD 3.29Å; L191-K220 WeakPolarHBondContact O-CD 3.42Å; L191-K220 VanDerWaalsContact O-CE 3.3Å; L191-K220 WeakPolarHBondContact O-CE 3.31Å; L191-K220 PolarHBondContact O-NZ 3.32Å; L192-K220 WeakPolarHBondContact O-CB 3.14Å; L192-K220 WeakPolarHBondContact O-CG 3.43Å; L192-K220 PolarHBondContact O-N 3.49Å; E218-K220 PolarHBondContact O-N 3.39Å; K220-P278 HydrophobicContact CB-CG 4.44Å; K220-P278 HydrophobicContact CG-CG 4.36Å
221L64.4Low76Confident35 Ų3528.2 Ų28.218%0.18315%0.153CC..PPolyproline II helixtrans-70155.7-174.2-76.3162.7000112.6P219 M271 P278 L293 T542P219-L221 PolarHBondContact O-N 3.39Å; L221-M271 HydrophobicContact CB-CE 4.2Å; L221-M271 HydrophobicContact CD1-CE 4.23Å; L221-P278 HydrophobicContact CB-CB 3.85Å; L221-P278 HydrophobicContact CD1-CB 3.26Å; L221-P278 HydrophobicContact CG-CB 3.39Å; L221-L293 HydrophobicContact CD1-CD1 3.7Å; L221-L293 HydrophobicContact CD1-CD2 3.28Å; L221-L293 HydrophobicContact CD1-CG 4Å; L221-L293 HydrophobicContact CD2-CD2 3.78Å; L221-L293 HydrophobicContact CG-CD2 4.06Å; L221-T542 HydrophobicContact CD2-CG2 3.6Å
222L61.5Low76.4Confident19 Ų1927.3 Ų27.310%0.09915%0.147CC..  trans-117.9134.4-178.8-56.2175.7000109C224 T542 V545 P620L222-C224 PolarHBondContact O-N 3.3Å; L222-T542 HydrophobicContact CB-CG2 4.49Å; L222-V545 HydrophobicContact CD1-CB 3.5Å; L222-V545 HydrophobicContact CD1-CG1 3.23Å; L222-V545 HydrophobicContact CD1-CG2 4.23Å; L222-P620 HydrophobicContact CB-CG 4.46Å; L222-P620 HydrophobicContact CD1-CG 3.4Å; L222-P620 HydrophobicContact CD2-CG 3.22Å; L222-P620 HydrophobicContact CG-CG 3.82Å
223N59.1Low76.6Confident63 Ų6327.9 Ų27.934%0.33715%0.15SC..  trans-78107.8167.5-172.3-3.2000108.7T225 N272N223-T225 PolarHBondContact OD1-N 3.45Å; N223-T225 PolarHBondContact OD1-OG1 3.03Å; N223-N272 PolarHBondContact ND2-OD1 3.41Å
224C55.9Low76.9Confident13 Ų1331.2 Ų31.29%0.08817%0.167CC..  trans-106.316.8-175.9-630000113.4L222 L541 V622L222-C224 PolarHBondContact O-N 3.3Å; C224-L541 HydrophobicContact CB-CB 4.48Å; C224-L541 HydrophobicContact CB-CD1 4.33Å; C224-V622 HydrophobicContact CB-CG2 4.36Å
225T54.6Low77.2Confident40 Ų4032.5 Ų32.525%0.24517%0.173CC..  trans-105.2134.1-170.858.50000111.8N223 I268 F292N223-T225 PolarHBondContact OD1-N 3.45Å; N223-T225 PolarHBondContact OD1-OG1 3.03Å; T225-I268 HydrophobicContact CG2-CG1 4.3Å; T225-I268 WeakPolarHBondContact OG1-CD1 3.49Å; T225-I268 WeakPolarHBondContact OG1-CG1 3.4Å; T225-F292 HydrophobicContact CG2-CD1 3.73Å; T225-F292 HydrophobicContact CG2-CE1 3.9Å
226A54.8Low77.6Confident55 Ų5532.2 Ų32.246%0.45517%0.172SC..  trans-122.9136.3176.200000110.4F228 G624A226-F228 VanDerWaalsContact C-N 3.33Å; A226-F228 PolarHBondContact O-N 2.91Å; A226-F228 VanDerWaalsContact O-N 3.11Å; A226-G624 WeakPolarHBondContact CB-O 3.46Å
227K63.4Low77.9Confident123 Ų12337 Ų3754%0.53519%0.193SC..  trans-86.268.5-179.8-62.8-165.9-167.5-162.90112.2S230 D265 I268K227-S230 PolarHBondContact O-OG 2.98Å; K227-D265 VanDerWaalsContact CD-OD1 3.24Å; K227-D265 WeakPolarHBondContact CD-OD1 3.24Å; K227-D265 VanDerWaalsContact CE-CG 3.44Å; K227-D265 WeakPolarHBondContact CE-OD1 3.46Å; K227-D265 IonicContact NZ-OD1 3.6Å; K227-D265 PolarHBondContact NZ-OD1 3.44Å; K227-D265 IonicContact NZ-OD2 2.72Å; K227-D265 PolarHBondContact NZ-OD2 3.47Å; K227-I268 HydrophobicContact CG-CD1 4.25Å
228F72.8Confident78.3Confident31 Ų3141.8 Ų41.814%0.13622%0.218CC..  trans-83.1-26.7-177.1174.5-97.2000114A226 S230 A355 L358 R359 D625A226-F228 VanDerWaalsContact C-N 3.33Å; A226-F228 PolarHBondContact O-N 2.91Å; A226-F228 VanDerWaalsContact O-N 3.11Å; F228-S230 PolarHBondContact O-N 3.09Å; F228-A355 HydrophobicContact CE1-CB 4.17Å; F228-A355 WeakPolarHBondContact CE1-O 3.26Å; F228-A355 WeakPolarHBondContact CZ-O 3.4Å; F228-L358 HydrophobicContact CE1-CB 3.44Å; F228-L358 VanDerWaalsContact CE1-CB 3.44Å; F228-L358 HydrophobicContact CE1-CD1 3.87Å; F228-L358 HydrophobicContact CE1-CG 4.29Å; F228-L358 HydrophobicContact CE2-CB 4.45Å; F228-L358 HydrophobicContact CZ-CB 3.32Å; F228-R359 HydrophobicContact CE2-CB 3.68Å; F228-R359 HydrophobicContact CE2-CG 4.21Å; F228-R359 HydrophobicContact CZ-CB 3.78Å; F228-R359 VanDerWaalsContact CZ-N 3.25Å; F228-D625 HydrophobicContact CB-CB 4.1Å; F228-D625 HydrophobicContact CD1-CB 3.93Å; F228-D625 HydrophobicContact CD2-CB 4.14Å; F228-D625 HydrophobicContact CE1-CB 4.38Å; F228-D625 VanDerWaalsContact CE2-OD2 3.25Å; F228-D625 WeakPolarHBondContact CE2-OD2 3.14Å; F228-D625 HydrophobicContact CG-CB 3.76Å; F228-D625 WeakPolarHBondContact CZ-OD2 3.47Å
229W85.8Confident78.9Confident13 Ų1341.8 Ų41.85%0.04922%0.218CC..THydrogen-bonded Turntrans-84.1-5.6-171.3-67.594.1000114.6F231 L232 L233 L257 L261 L351 V354 A355 L358 L530W229-F231 VanDerWaalsContact C-N 3.26Å; W229-F231 PolarHBondContact O-N 2.87Å; W229-L232 HydrophobicContact CE3-CD2 4Å; W229-L232 HydrophobicContact CZ3-CD2 4.06Å; W229-L232 PolarHBondContact O-N 3.2Å; W229-L233 PolarHBondContact O-N 2.88Å; W229-L257 HydrophobicContact CB-CD1 4.3Å; W229-L261 HydrophobicContact CB-CD1 4.34Å; W229-L261 HydrophobicContact CB-CD2 3.65Å; W229-L351 HydrophobicContact CH2-CD2 3.73Å; W229-L351 HydrophobicContact CZ2-CD2 4.07Å; W229-V354 HydrophobicContact CH2-CB 4.03Å; W229-V354 HydrophobicContact CH2-CG1 3.46Å; W229-V354 VanDerWaalsContact CH2-CG1 3.46Å; W229-V354 HydrophobicContact CZ3-CG1 3.48Å; W229-V354 VanDerWaalsContact CZ3-CG1 3.48Å; W229-A355 HydrophobicContact CZ2-CB 4.47Å; W229-L358 HydrophobicContact CE3-CD1 3.72Å; W229-L358 HydrophobicContact CH2-CD1 4.4Å; W229-L358 HydrophobicContact CZ3-CD1 3.67Å; W229-L530 HydrophobicContact CD2-CD1 4.23Å; W229-L530 HydrophobicContact CD2-CD2 3.85Å; W229-L530 VanDerWaalsContact CE2-CD1 3.43Å; W229-L530 HydrophobicContact CE3-CD2 4.27Å; W229-L530 HydrophobicContact CG-CD2 4.06Å; W229-L530 HydrophobicContact CZ2-CD1 3.65Å; W229-L530 HydrophobicContact CZ2-CD2 4.4Å; W229-L530 VanDerWaalsContact NE1-CD1 3.27Å
230S87.9Confident79.5Confident48 Ų4847.3 Ų47.334%0.33624%0.243SC..Hα-helixtrans-60.2-38.117552.50000111.5K227 F228 L232 L233 D234K227-S230 PolarHBondContact O-OG 2.98Å; F228-S230 PolarHBondContact O-N 3.09Å; S230-L232 VanDerWaalsContact C-N 3.28Å; S230-L232 PolarHBondContact O-N 3.32Å; S230-L233 WeakPolarHBondContact O-CB 3.37Å; S230-L233 PolarHBondContact O-N 3.04Å; S230-D234 WeakPolarHBondContact O-CB 3.41Å; S230-D234 PolarHBondContact O-N 3.43Å
231F90.8Very high80.5Confident19 Ų1944 Ų448%0.08323%0.228CC..Hα-helixtrans-50.1-48.8174.1173.3-86.9000111.8W229 D234 H235 L358 M361 E365 V506W229-F231 VanDerWaalsContact C-N 3.26Å; W229-F231 PolarHBondContact O-N 2.87Å; F231-D234 PolarHBondContact O-N 2.69Å; F231-H235 AromaticContact CD2-CD2 3.73Å; F231-H235 AromaticContact CD2-NE2 3.84Å; F231-H235 AromaticContact CE1-CD2 3.75Å; F231-H235 AromaticContact CE2-CD2 3.42Å; F231-H235 VanDerWaalsContact CE2-CD2 3.42Å; F231-H235 WeakPolarHBondContact CE2-CD2 3.33Å; F231-H235 AromaticContact CE2-NE2 3.23Å; F231-H235 WeakPolarHBondContact CE2-NE2 3.23Å; F231-H235 AromaticContact CZ-CD2 3.4Å; F231-H235 WeakPolarHBondContact CZ-CD2 3.31Å; F231-H235 AromaticContact CZ-NE2 3.47Å; F231-H235 WeakPolarHBondContact CZ-NE2 3.35Å; F231-H235 PolarHBondContact O-CD2 3.09Å; F231-H235 VanDerWaalsContact O-CD2 3.27Å; F231-H235 PolarHBondContact O-N 3.24Å; F231-H235 VanDerWaalsContact O-N 3.13Å; F231-L358 HydrophobicContact CD1-CD2 3.93Å; F231-L358 HydrophobicContact CE1-CD2 4.01Å; F231-M361 HydrophobicContact CE1-CB 3.89Å; F231-M361 HydrophobicContact CE1-SD 4.19Å; F231-M361 HydrophobicContact CE2-CB 4.45Å; F231-M361 HydrophobicContact CZ-CB 3.61Å; F231-E365 VanDerWaalsContact CE2-OE2 3.29Å; F231-E365 WeakPolarHBondContact CE2-OE2 3.27Å; F231-V506 HydrophobicContact CE1-CG1 4.35Å; F231-V506 HydrophobicContact CZ-CG1 4.29Å; F231-V506 HydrophobicContact CZ-CG2 4.08Å
232L93.4Very high82Confident1 Ų143.1 Ų43.11%0.00522%0.224CC..Hα-helixtrans-66.3-41179.9179.462000111.4W229 S230 M236 L257 L358 I510 M513W229-L232 HydrophobicContact CE3-CD2 4Å; W229-L232 HydrophobicContact CZ3-CD2 4.06Å; W229-L232 PolarHBondContact O-N 3.2Å; S230-L232 VanDerWaalsContact C-N 3.28Å; S230-L232 PolarHBondContact O-N 3.32Å; L232-M236 HydrophobicContact CD1-CE 4.33Å; L232-M236 HydrophobicContact CD1-CG 4.28Å; L232-M236 HydrophobicContact CD1-SD 4.42Å; L232-M236 HydrophobicContact CD2-CE 4.23Å; L232-M236 HydrophobicContact CG-CE 3.72Å; L232-M236 HydrophobicContact CG-SD 4.41Å; L232-M236 WeakPolarHBondContact O-CB 3.35Å; L232-M236 VanDerWaalsContact O-CG 3.29Å; L232-M236 WeakPolarHBondContact O-CG 3.31Å; L232-M236 PolarHBondContact O-N 3.49Å; L232-L257 HydrophobicContact CB-CD2 4.27Å; L232-L257 HydrophobicContact CD2-CD2 4.13Å; L232-L257 HydrophobicContact CG-CD2 4.12Å; L232-L358 HydrophobicContact CB-CD1 4.01Å; L232-L358 HydrophobicContact CB-CD2 4.22Å; L232-L358 HydrophobicContact CD1-CD2 4.2Å; L232-L358 HydrophobicContact CD2-CD1 4.24Å; L232-I510 HydrophobicContact CD1-CD1 4.4Å; L232-I510 HydrophobicContact CD1-CG1 3.88Å; L232-M513 HydrophobicContact CD2-CE 4.33Å; L232-M513 HydrophobicContact CD2-SD 4.01Å
233L94.9Very high83.6Confident13 Ų1344.6 Ų44.67%0.06824%0.235CC..Hα-helixtrans-63.7-43.5178.4-177.259.6000112W229 S230 M236 K237 V254 L257 L261W229-L233 PolarHBondContact O-N 2.88Å; S230-L233 WeakPolarHBondContact O-CB 3.37Å; S230-L233 PolarHBondContact O-N 3.04Å; L233-M236 PolarHBondContact O-N 3.39Å; L233-K237 HydrophobicContact CD1-CD 4.48Å; L233-K237 HydrophobicContact CD1-CG 4.48Å; L233-K237 HydrophobicContact CG-CD 4.3Å; L233-K237 WeakPolarHBondContact O-CG 3.49Å; L233-K237 PolarHBondContact O-N 3.26Å; L233-V254 HydrophobicContact CD1-CB 4.43Å; L233-V254 HydrophobicContact CD1-CG1 4.02Å; L233-L257 HydrophobicContact CB-CD2 3.76Å; L233-L257 HydrophobicContact CB-CG 4.26Å; L233-L257 HydrophobicContact CD1-CB 4.36Å; L233-L257 HydrophobicContact CD1-CD2 4.29Å; L233-L257 HydrophobicContact CD1-CG 4.35Å; L233-L261 HydrophobicContact CB-CD1 4.21Å; L233-L261 HydrophobicContact CD2-CD1 3.88Å
234D93.7Very high85.2Confident81 Ų8150.5 Ų50.543%0.43326%0.257SS..Hα-helixtrans-65.4-48-178.2-65.7-23.8000110.7S230 F231 M236 K237 N238S230-D234 WeakPolarHBondContact O-CB 3.41Å; S230-D234 PolarHBondContact O-N 3.43Å; F231-D234 PolarHBondContact O-N 2.69Å; D234-M236 PolarHBondContact O-N 3.16Å; D234-K237 PolarHBondContact O-N 3.14Å; D234-N238 PolarHBondContact O-N 3.31Å; D234-N238 VanDerWaalsContact O-N 3.09Å; D234-N238 PolarHBondContact O-ND2 2.86Å
235H95Very high87Confident26 Ų2655.9 Ų55.912%0.1229%0.285CS..Hα-helixtrans-64.5-36.3175.7-79.4-75.2000112.7F231 N238 L239 E365 V506 I510F231-H235 AromaticContact CD2-CD2 3.73Å; F231-H235 AromaticContact CD2-NE2 3.84Å; F231-H235 AromaticContact CE1-CD2 3.75Å; F231-H235 AromaticContact CE2-CD2 3.42Å; F231-H235 VanDerWaalsContact CE2-CD2 3.42Å; F231-H235 WeakPolarHBondContact CE2-CD2 3.33Å; F231-H235 AromaticContact CE2-NE2 3.23Å; F231-H235 WeakPolarHBondContact CE2-NE2 3.23Å; F231-H235 AromaticContact CZ-CD2 3.4Å; F231-H235 WeakPolarHBondContact CZ-CD2 3.31Å; F231-H235 AromaticContact CZ-NE2 3.47Å; F231-H235 WeakPolarHBondContact CZ-NE2 3.35Å; F231-H235 PolarHBondContact O-CD2 3.09Å; F231-H235 VanDerWaalsContact O-CD2 3.27Å; F231-H235 PolarHBondContact O-N 3.24Å; F231-H235 VanDerWaalsContact O-N 3.13Å; H235-N238 PolarHBondContact O-N 3.24Å; H235-L239 PolarHBondContact O-N 3.41Å; H235-E365 IonicContact CE1-OE2 3.96Å; H235-E365 IonicContact NE2-OE2 3.76Å; H235-E365 PolarHBondContact NE2-OE2 3.49Å; H235-V506 HydrophobicContact CB-CG1 3.91Å; H235-I510 HydrophobicContact CB-CD1 3.64Å
236M96.2Very high88.9Confident0 Ų054.4 Ų54.40%028%0.276CS..Hα-helixtrans-65.8-37.6173.7-78-168.3-64.600112.8L232 L233 D234 N238 K250 H253 V254 L257 I510L232-M236 HydrophobicContact CD1-CE 4.33Å; L232-M236 HydrophobicContact CD1-CG 4.28Å; L232-M236 HydrophobicContact CD1-SD 4.42Å; L232-M236 HydrophobicContact CD2-CE 4.23Å; L232-M236 HydrophobicContact CG-CE 3.72Å; L232-M236 HydrophobicContact CG-SD 4.41Å; L232-M236 WeakPolarHBondContact O-CB 3.35Å; L232-M236 VanDerWaalsContact O-CG 3.29Å; L232-M236 WeakPolarHBondContact O-CG 3.31Å; L232-M236 PolarHBondContact O-N 3.49Å; L233-M236 PolarHBondContact O-N 3.39Å; D234-M236 PolarHBondContact O-N 3.16Å; M236-N238 VanDerWaalsContact C-N 3.34Å; M236-K250 VanDerWaalsContact O-CD 3.27Å; M236-K250 WeakPolarHBondContact O-CD 3.15Å; M236-K250 WeakPolarHBondContact O-CE 3.4Å; M236-H253 HydrophobicContact SD-CB 3.96Å; M236-V254 HydrophobicContact CB-CG2 3.82Å; M236-L257 HydrophobicContact CE-CB 4.33Å; M236-L257 HydrophobicContact CE-CD2 3.38Å; M236-L257 HydrophobicContact CE-CG 4.49Å; M236-I510 HydrophobicContact CG-CD1 3.96Å; M236-I510 HydrophobicContact CG-CG1 4.14Å; M236-I510 HydrophobicContact CG-CG2 3.72Å; M236-I510 HydrophobicContact SD-CG2 4.46Å
237K95.9Very high90.9Very high101 Ų10154.1 Ų54.144%0.43927%0.266SS..Hα-helixtrans-66.1-38177-77.71741771750111.9L233 D234 L239 H240 V254L233-K237 HydrophobicContact CD1-CD 4.48Å; L233-K237 HydrophobicContact CD1-CG 4.48Å; L233-K237 HydrophobicContact CG-CD 4.3Å; L233-K237 WeakPolarHBondContact O-CG 3.49Å; L233-K237 PolarHBondContact O-N 3.26Å; D234-K237 PolarHBondContact O-N 3.14Å; K237-L239 VanDerWaalsContact C-N 3.33Å; K237-H240 PolarHBondContact O-CE1 3.05Å; K237-V254 HydrophobicContact CG-CG1 3.93Å; K237-V254 HydrophobicContact CG-CG2 4.42Å
238N92.3Very high92.4Very high101 Ų10151 Ų5154%0.5426%0.264SS..Hα-helixtrans-84-2.8-176.6-64.2-33.9000114.3D234 H235 M236 H240D234-N238 PolarHBondContact O-N 3.31Å; D234-N238 VanDerWaalsContact O-N 3.09Å; D234-N238 PolarHBondContact O-ND2 2.86Å; H235-N238 PolarHBondContact O-N 3.24Å; M236-N238 VanDerWaalsContact C-N 3.34Å; N238-H240 WeakPolarHBondContact CA-NE2 3.46Å; N238-H240 PolarHBondContact O-CD2 3.2Å; N238-H240 PolarHBondContact O-N 3.36Å; N238-H240 PolarHBondContact O-NE2 3.43Å
239L93.9Very high93.5Very high0 Ų053.3 Ų53.30%027%0.272CS..  trans-85.593.9178.2178.554.6000110.9H235 K237 Y241 L242 K250 H507 I510 V511H235-L239 PolarHBondContact O-N 3.41Å; K237-L239 VanDerWaalsContact C-N 3.33Å; L239-Y241 HydrophobicContact CD1-CD1 4.04Å; L239-Y241 HydrophobicContact CD1-CD2 4.44Å; L239-Y241 HydrophobicContact CD1-CE1 3.41Å; L239-Y241 VanDerWaalsContact CD1-CE1 3.41Å; L239-Y241 HydrophobicContact CD1-CE2 3.89Å; L239-L242 HydrophobicContact CD1-CD2 4.12Å; L239-L242 HydrophobicContact CD1-CG 4.27Å; L239-L242 HydrophobicContact CD2-CD1 3.82Å; L239-L242 HydrophobicContact CD2-CD2 4.09Å; L239-L242 HydrophobicContact CD2-CG 4.1Å; L239-L242 HydrophobicContact CG-CD1 3.98Å; L239-L242 HydrophobicContact CG-CD2 4.1Å; L239-L242 HydrophobicContact CG-CG 3.85Å; L239-K250 HydrophobicContact CB-CD 4.37Å; L239-K250 PolarHBondContact O-NZ 3.04Å; L239-H507 HydrophobicContact CD1-CB 4.26Å; L239-I510 HydrophobicContact CD2-CB 4.29Å; L239-I510 HydrophobicContact CD2-CG2 3.69Å; L239-V511 HydrophobicContact CD2-CG2 4.31Å
240H91.1Very high94Very high121 Ų12152.9 Ų52.956%0.5627%0.27SS*.  trans-105.6-7.7-166.8-61.2-58.4000116.7K237 N238K237-H240 PolarHBondContact O-CE1 3.05Å; N238-H240 WeakPolarHBondContact CA-NE2 3.46Å; N238-H240 PolarHBondContact O-CD2 3.2Å; N238-H240 PolarHBondContact O-N 3.36Å; N238-H240 PolarHBondContact O-NE2 3.43Å
241Y93.1Very high94.4Very high21 Ų2155 Ų558%0.08227%0.274CS..  trans-103.415.4-170.956-95.5000113.2L239 L423 W426 F427 V444 H507L239-Y241 HydrophobicContact CD1-CD1 4.04Å; L239-Y241 HydrophobicContact CD1-CD2 4.44Å; L239-Y241 HydrophobicContact CD1-CE1 3.41Å; L239-Y241 VanDerWaalsContact CD1-CE1 3.41Å; L239-Y241 HydrophobicContact CD1-CE2 3.89Å; Y241-L423 HydrophobicContact CE2-CD2 3.64Å; Y241-W426 HydrophobicContact CD2-CB 4.13Å; Y241-W426 WeakPolarHBondContact O-CB 3.19Å; Y241-F427 AromaticContact CD1-CD2 3.82Å; Y241-F427 HydrophobicContact CD1-CD2 3.82Å; Y241-F427 HydrophobicContact CD2-CB 4.03Å; Y241-F427 AromaticContact CE1-CD2 3.94Å; Y241-F427 HydrophobicContact CE1-CD2 3.94Å; Y241-F427 HydrophobicContact CE2-CB 4.21Å; Y241-F427 HydrophobicContact CG-CB 4.28Å; Y241-F427 HydrophobicContact CG-CD2 4.14Å; Y241-V444 HydrophobicContact CE1-CG2 4.11Å; Y241-V444 WeakPolarHBondContact OH-CG2 3.4Å; Y241-H507 AromaticContact CE1-CE1 3.93Å; Y241-H507 AromaticContact CE1-ND1 3.82Å; Y241-H507 AromaticContact CZ-ND1 3.64Å; Y241-H507 WeakPolarHBondContact OH-CB 3.43Å; Y241-H507 VanDerWaalsContact OH-CG 3.32Å; Y241-H507 PolarHBondContact OH-ND1 3.44Å
242L95.4Very high94.7Very high17 Ų1757 Ų579%0.08929%0.288CS..  trans-72.9151178.4-61.6-175.5000112.2L239 L246 D247 K250 L423 W426 V511 L514L239-L242 HydrophobicContact CD1-CD2 4.12Å; L239-L242 HydrophobicContact CD1-CG 4.27Å; L239-L242 HydrophobicContact CD2-CD1 3.82Å; L239-L242 HydrophobicContact CD2-CD2 4.09Å; L239-L242 HydrophobicContact CD2-CG 4.1Å; L239-L242 HydrophobicContact CG-CD1 3.98Å; L239-L242 HydrophobicContact CG-CD2 4.1Å; L239-L242 HydrophobicContact CG-CG 3.85Å; L242-L246 HydrophobicContact CB-CB 4.18Å; L242-L246 HydrophobicContact CD1-CB 4.22Å; L242-D247 HydrophobicContact CB-CB 4.34Å; L242-K250 HydrophobicContact CD1-CB 4.29Å; L242-K250 HydrophobicContact CD1-CD 3.96Å; L242-K250 HydrophobicContact CD1-CG 4.45Å; L242-L423 HydrophobicContact CD2-CD2 4.43Å; L242-W426 HydrophobicContact CD2-CE3 4.03Å; L242-W426 HydrophobicContact CD2-CZ3 4.13Å; L242-V511 HydrophobicContact CD2-CG2 3.72Å; L242-L514 HydrophobicContact CD1-CD1 3.83Å
243P95.4Very high94.9Very high50 Ų5057 Ų5733%0.32529%0.288SS..  trans-64.5155.5169.528.5-35.1000111.1D245 L246 D247 W426P243-D245 VanDerWaalsContact C-N 3.3Å; P243-D245 PolarHBondContact O-N 2.97Å; P243-D245 VanDerWaalsContact O-N 3.11Å; P243-L246 HydrophobicContact CG-CB 4.09Å; P243-L246 HydrophobicContact CG-CD1 3.82Å; P243-L246 HydrophobicContact CG-CG 4.13Å; P243-L246 PolarHBondContact O-N 3.42Å; P243-D247 PolarHBondContact O-N 3.31Å; P243-W426 HydrophobicContact CG-CD2 4.29Å; P243-W426 HydrophobicContact CG-CH2 4.39Å; P243-W426 HydrophobicContact CG-CZ2 3.99Å
244K93.5Very high95Very high187 Ų18757.2 Ų57.281%0.81329%0.29SS*.Hα-helixtrans-48.9-44.1-171.6-67.9-176.9178.31790114.3D247 A248K244-D247 PolarHBondContact O-N 3.47Å; K244-A248 WeakPolarHBondContact O-CB 3.35Å; K244-A248 PolarHBondContact O-N 2.81Å
245D93.1Very high95.1Very high125 Ų12560.5 Ų60.567%0.66830%0.303SS*.Hα-helixtrans-70-33.9-177.4-61.2-30.7000113.3P243 R249P243-D245 VanDerWaalsContact C-N 3.3Å; P243-D245 PolarHBondContact O-N 2.97Å; P243-D245 VanDerWaalsContact O-N 3.11Å; D245-R249 PolarHBondContact O-N 3.05Å; D245-R249 PolarHBondContact O-NE 3.37Å
246L95.3Very high95.1Very high10 Ų1060.5 Ų60.55%0.05231%0.308CS..Hα-helixtrans-78.3-36.1174.6-75.4178.3000111.1L242 P243 R249 K250 W426 V511 N515L242-L246 HydrophobicContact CB-CB 4.18Å; L242-L246 HydrophobicContact CD1-CB 4.22Å; P243-L246 HydrophobicContact CG-CB 4.09Å; P243-L246 HydrophobicContact CG-CD1 3.82Å; P243-L246 HydrophobicContact CG-CG 4.13Å; P243-L246 PolarHBondContact O-N 3.42Å; L246-R249 PolarHBondContact O-N 3.47Å; L246-K250 WeakPolarHBondContact O-CB 3.48Å; L246-K250 PolarHBondContact O-N 3.3Å; L246-W426 HydrophobicContact CD1-CH2 3.4Å; L246-W426 HydrophobicContact CD1-CZ2 4.16Å; L246-W426 HydrophobicContact CD1-CZ3 3.73Å; L246-V511 HydrophobicContact CD1-CG1 4.36Å; L246-N515 WeakPolarHBondContact CD2-OD1 3.44Å
247D96.1Very high95Very high48 Ų4860.5 Ų60.526%0.25731%0.308SS..Hα-helixtrans-62.6-44.7174.6-169.165.5000111.1L242 P243 K244 R249 K250 Q251L242-D247 HydrophobicContact CB-CB 4.34Å; P243-D247 PolarHBondContact O-N 3.31Å; K244-D247 PolarHBondContact O-N 3.47Å; D247-R249 VanDerWaalsContact C-N 3.31Å; D247-R249 PolarHBondContact O-N 3.03Å; D247-K250 VanDerWaalsContact O-CB 3.3Å; D247-K250 WeakPolarHBondContact O-CB 3.5Å; D247-K250 PolarHBondContact O-N 2.88Å; D247-K250 VanDerWaalsContact O-N 3.12Å; D247-K250 WeakPolarHBondContact OD1-CE 3.24Å; D247-K250 IonicContact OD1-NZ 3.85Å; D247-K250 PolarHBondContact OD1-NZ 2.94Å; D247-Q251 WeakPolarHBondContact O-CG 3.13Å; D247-Q251 PolarHBondContact O-N 3.46Å
248A95.6Very high94.9Very high59 Ų5956.7 Ų56.749%0.48830%0.297SS..Hα-helixtrans-57.2-43.6174.400000112.1K244 Q251 V252K244-A248 WeakPolarHBondContact O-CB 3.35Å; K244-A248 PolarHBondContact O-N 2.81Å; A248-Q251 PolarHBondContact O-N 3.08Å; A248-V252 PolarHBondContact O-N 3.44Å
249R95.3Very high94.9Very high79 Ų7954.5 Ų54.530%0.29829%0.293SS..Hα-helixtrans-63-46.2173.8-79-176.6-96.6170.1-11.2111.9D245 L246 D247 Q251 V252 H253D245-R249 PolarHBondContact O-N 3.05Å; D245-R249 PolarHBondContact O-NE 3.37Å; L246-R249 PolarHBondContact O-N 3.47Å; D247-R249 VanDerWaalsContact C-N 3.31Å; D247-R249 PolarHBondContact O-N 3.03Å; R249-Q251 VanDerWaalsContact C-N 3.26Å; R249-Q251 PolarHBondContact O-N 3.11Å; R249-V252 WeakPolarHBondContact O-CB 3.39Å; R249-V252 PolarHBondContact O-N 3.02Å; R249-V252 VanDerWaalsContact O-N 3.08Å; R249-H253 PolarHBondContact O-CD2 2.93Å; R249-H253 PolarHBondContact O-N 3.23Å; R249-H253 VanDerWaalsContact O-N 3.13Å
250K96.9Very high94.7Very high4 Ų454.8 Ų54.82%0.01730%0.295CS..Hα-helixtrans-53.7-42.5175.3-170.2-160.882.7-165.80111.5M236 L239 L242 L246 D247 V252 H253 V254 L514M236-K250 VanDerWaalsContact O-CD 3.27Å; M236-K250 WeakPolarHBondContact O-CD 3.15Å; M236-K250 WeakPolarHBondContact O-CE 3.4Å; L239-K250 HydrophobicContact CB-CD 4.37Å; L239-K250 PolarHBondContact O-NZ 3.04Å; L242-K250 HydrophobicContact CD1-CB 4.29Å; L242-K250 HydrophobicContact CD1-CD 3.96Å; L242-K250 HydrophobicContact CD1-CG 4.45Å; L246-K250 WeakPolarHBondContact O-CB 3.48Å; L246-K250 PolarHBondContact O-N 3.3Å; D247-K250 VanDerWaalsContact O-CB 3.3Å; D247-K250 WeakPolarHBondContact O-CB 3.5Å; D247-K250 PolarHBondContact O-N 2.88Å; D247-K250 VanDerWaalsContact O-N 3.12Å; D247-K250 WeakPolarHBondContact OD1-CE 3.24Å; D247-K250 IonicContact OD1-NZ 3.85Å; D247-K250 PolarHBondContact OD1-NZ 2.94Å; K250-V252 VanDerWaalsContact C-N 3.34Å; K250-V252 PolarHBondContact O-N 2.81Å; K250-H253 WeakPolarHBondContact O-CB 3.35Å; K250-H253 PolarHBondContact O-N 3.47Å; K250-H253 VanDerWaalsContact O-N 3.13Å; K250-V254 HydrophobicContact CG-CG2 4.4Å; K250-V254 WeakPolarHBondContact O-CG2 3.45Å; K250-V254 PolarHBondContact O-N 3.44Å; K250-L514 HydrophobicContact CB-CD1 3.84Å; K250-L514 HydrophobicContact CB-CD2 4.3Å; K250-L514 HydrophobicContact CG-CD1 4.22Å
251Q96.6Very high94.6Very high91 Ų9150 Ų5043%0.42527%0.273SS..Hα-helixtrans-61.5-40.2178.1-63.1-52.3-29.900112.6D247 A248 R249 H253 V254 Q255D247-Q251 WeakPolarHBondContact O-CG 3.13Å; D247-Q251 PolarHBondContact O-N 3.46Å; A248-Q251 PolarHBondContact O-N 3.08Å; R249-Q251 VanDerWaalsContact C-N 3.26Å; R249-Q251 PolarHBondContact O-N 3.11Å; Q251-H253 VanDerWaalsContact C-N 3.31Å; Q251-H253 PolarHBondContact O-N 3.37Å; Q251-V254 PolarHBondContact O-N 2.93Å; Q251-Q255 WeakPolarHBondContact O-CB 3.38Å; Q251-Q255 PolarHBondContact O-N 3.41Å
252V96.5Very high94.4Very high62 Ų6255 Ų5538%0.37630%0.297SS..Hα-helixtrans-61.5-42174.4-177.80000110.7A248 R249 K250 A256 V523A248-V252 PolarHBondContact O-N 3.44Å; R249-V252 WeakPolarHBondContact O-CB 3.39Å; R249-V252 PolarHBondContact O-N 3.02Å; R249-V252 VanDerWaalsContact O-N 3.08Å; K250-V252 VanDerWaalsContact C-N 3.34Å; K250-V252 PolarHBondContact O-N 2.81Å; V252-A256 WeakPolarHBondContact O-CB 3.42Å; V252-A256 PolarHBondContact O-N 3.44Å; V252-V523 HydrophobicContact CG1-CG1 4.14Å
253H97.1Very high93.8Very high0 Ų056.5 Ų56.50%030%0.303CS..Hα-helixtrans-64-46.2175.5-82-104.9000113M236 R249 K250 Q251 Q255 A256 L257 L514 V523 Y527M236-H253 HydrophobicContact SD-CB 3.96Å; R249-H253 PolarHBondContact O-CD2 2.93Å; R249-H253 PolarHBondContact O-N 3.23Å; R249-H253 VanDerWaalsContact O-N 3.13Å; K250-H253 WeakPolarHBondContact O-CB 3.35Å; K250-H253 PolarHBondContact O-N 3.47Å; K250-H253 VanDerWaalsContact O-N 3.13Å; Q251-H253 VanDerWaalsContact C-N 3.31Å; Q251-H253 PolarHBondContact O-N 3.37Å; H253-Q255 VanDerWaalsContact C-N 3.32Å; H253-Q255 PolarHBondContact O-N 3.21Å; H253-A256 PolarHBondContact O-N 3.35Å; H253-L257 VanDerWaalsContact O-CB 3.3Å; H253-L257 WeakPolarHBondContact O-CB 3.32Å; H253-L257 PolarHBondContact O-N 2.84Å; H253-L514 HydrophobicContact CB-CD2 4.13Å; H253-L514 WeakPolarHBondContact CD2-CD2 3.33Å; H253-V523 VanDerWaalsContact NE2-CG2 3.26Å; H253-V523 WeakPolarHBondContact NE2-CG2 3.49Å; H253-Y527 HydrophobicContact CB-CE2 4.38Å; H253-Y527 AromaticContact ND1-CE2 3.86Å; H253-Y527 AromaticContact ND1-CZ 3.8Å; H253-Y527 PolarHBondContact ND1-OH 3.37Å
254V96.6Very high93.3Very high19 Ų1955.1 Ų55.112%0.11529%0.293CS..Hα-helixtrans-60.6-44.1179167.80000110.5L233 M236 K237 K250 Q251 G258L233-V254 HydrophobicContact CD1-CB 4.43Å; L233-V254 HydrophobicContact CD1-CG1 4.02Å; M236-V254 HydrophobicContact CB-CG2 3.82Å; K237-V254 HydrophobicContact CG-CG1 3.93Å; K237-V254 HydrophobicContact CG-CG2 4.42Å; K250-V254 HydrophobicContact CG-CG2 4.4Å; K250-V254 WeakPolarHBondContact O-CG2 3.45Å; K250-V254 PolarHBondContact O-N 3.44Å; Q251-V254 PolarHBondContact O-N 2.93Å; V254-G258 WeakPolarHBondContact O-CA 3.4Å; V254-G258 PolarHBondContact O-N 3.06Å
255Q96Very high92.8Very high150 Ų15048.7 Ų48.770%0.70127%0.267SS*.Hα-helixtrans-64.2-48.1177.6-173.2-179.112.100111.6Q251 H253 G258 A259Q251-Q255 WeakPolarHBondContact O-CB 3.38Å; Q251-Q255 PolarHBondContact O-N 3.41Å; H253-Q255 VanDerWaalsContact C-N 3.32Å; H253-Q255 PolarHBondContact O-N 3.21Å; Q255-G258 PolarHBondContact O-N 2.72Å; Q255-A259 WeakPolarHBondContact O-CB 3.27Å; Q255-A259 PolarHBondContact O-N 2.94Å
256A94.8Very high92.2Very high26 Ų2646.4 Ų46.422%0.21526%0.255CS..Hα-helixtrans-69.9-41.6-176.600000112.8V252 H253 C260 V523 Y527V252-A256 WeakPolarHBondContact O-CB 3.42Å; V252-A256 PolarHBondContact O-N 3.44Å; H253-A256 PolarHBondContact O-N 3.35Å; A256-C260 PolarHBondContact O-N 3.33Å; A256-V523 HydrophobicContact CB-CG1 4.23Å; A256-Y527 HydrophobicContact CB-CD2 3.36Å; A256-Y527 HydrophobicContact CB-CE2 3.76Å; A256-Y527 HydrophobicContact CB-CG 4.22Å
257L94Very high91.5Very high0 Ų046.3 Ų46.30%026%0.255CS..Hα-helixtrans-65.5-47173.4-179.455.6000110.6W229 L232 L233 M236 H253 A259 C260 L261 Y527 L530W229-L257 HydrophobicContact CB-CD1 4.3Å; L232-L257 HydrophobicContact CB-CD2 4.27Å; L232-L257 HydrophobicContact CD2-CD2 4.13Å; L232-L257 HydrophobicContact CG-CD2 4.12Å; L233-L257 HydrophobicContact CB-CD2 3.76Å; L233-L257 HydrophobicContact CB-CG 4.26Å; L233-L257 HydrophobicContact CD1-CB 4.36Å; L233-L257 HydrophobicContact CD1-CD2 4.29Å; L233-L257 HydrophobicContact CD1-CG 4.35Å; M236-L257 HydrophobicContact CE-CB 4.33Å; M236-L257 HydrophobicContact CE-CD2 3.38Å; M236-L257 HydrophobicContact CE-CG 4.49Å; H253-L257 VanDerWaalsContact O-CB 3.3Å; H253-L257 WeakPolarHBondContact O-CB 3.32Å; H253-L257 PolarHBondContact O-N 2.84Å; L257-A259 VanDerWaalsContact C-N 3.32Å; L257-A259 PolarHBondContact O-N 3.44Å; L257-C260 PolarHBondContact O-N 3.35Å; L257-C260 VanDerWaalsContact O-N 3.12Å; L257-L261 HydrophobicContact CD1-CD1 4.26Å; L257-L261 HydrophobicContact CD1-CD2 4Å; L257-L261 HydrophobicContact CD1-CG 3.91Å; L257-L261 HydrophobicContact CG-CD1 4.22Å; L257-L261 HydrophobicContact CG-CG 4.21Å; L257-L261 WeakPolarHBondContact O-CG 3.31Å; L257-L261 PolarHBondContact O-N 3.46Å; L257-Y527 HydrophobicContact CB-CD1 4.17Å; L257-Y527 HydrophobicContact CB-CE1 3.65Å; L257-Y527 HydrophobicContact CB-CE2 4.39Å; L257-Y527 HydrophobicContact CD1-CD1 4.01Å; L257-Y527 HydrophobicContact CD1-CE1 3.81Å; L257-Y527 HydrophobicContact CD2-CE1 4.41Å; L257-Y527 HydrophobicContact CG-CE1 4.15Å; L257-L530 HydrophobicContact CD1-CD2 4.14Å
258G93.7Very high90.5Very high20 Ų2045.1 Ų45.121%0.20625%0.248CC..Hα-helixtrans-53.9-47.6177.500000112.3V254 Q255 L261 E262V254-G258 WeakPolarHBondContact O-CA 3.4Å; V254-G258 PolarHBondContact O-N 3.06Å; Q255-G258 PolarHBondContact O-N 2.72Å; G258-L261 PolarHBondContact O-N 3.44Å; G258-E262 WeakPolarHBondContact O-CB 3.34Å; G258-E262 PolarHBondContact O-N 2.9Å
259A92.2Very high89.4Confident55 Ų5544 Ų4446%0.45523%0.233SC..Hα-helixtrans-64.8-38.8176.700000113.1Q255 L257 K263Q255-A259 WeakPolarHBondContact O-CB 3.27Å; Q255-A259 PolarHBondContact O-N 2.94Å; L257-A259 VanDerWaalsContact C-N 3.32Å; L257-A259 PolarHBondContact O-N 3.44Å; A259-K263 WeakPolarHBondContact O-CB 3.31Å; A259-K263 PolarHBondContact O-N 3.1Å; A259-K263 VanDerWaalsContact O-N 3.08Å
260C90.1Very high88.5Confident7 Ų740.7 Ų40.75%0.04722%0.221CC..Hα-helixtrans-65.4-44.1174.6-175.80000110.4A256 L257 K263 L264 C531A256-C260 PolarHBondContact O-N 3.33Å; L257-C260 PolarHBondContact O-N 3.35Å; L257-C260 VanDerWaalsContact O-N 3.12Å; C260-K263 WeakPolarHBondContact O-CB 3.41Å; C260-K263 PolarHBondContact O-N 2.96Å; C260-L264 VanDerWaalsContact O-CG 3.31Å; C260-L264 WeakPolarHBondContact O-CG 3.46Å; C260-L264 PolarHBondContact O-N 3.26Å; C260-C531 VanDerWaalsContact CA-SG 3.58Å; C260-C531 WeakPolarHBondContact CB-SG 3.26Å; C260-C531 WeakPolarHBondContact SG-CB 3.35Å; C260-C531 CovalentContact SG-SG 2.07Å; C260-C531 PolarHBondContact SG-SG 3.13Å
261L89.4Confident87.2Confident19 Ų1941.8 Ų41.810%0.09923%0.226CC..Hα-helixtrans-65.2-41.4178-61.3-169.9000112.9W229 L233 L257 G258 K263 L264 D265W229-L261 HydrophobicContact CB-CD1 4.34Å; W229-L261 HydrophobicContact CB-CD2 3.65Å; L233-L261 HydrophobicContact CB-CD1 4.21Å; L233-L261 HydrophobicContact CD2-CD1 3.88Å; L257-L261 HydrophobicContact CD1-CD1 4.26Å; L257-L261 HydrophobicContact CD1-CD2 4Å; L257-L261 HydrophobicContact CD1-CG 3.91Å; L257-L261 HydrophobicContact CG-CD1 4.22Å; L257-L261 HydrophobicContact CG-CG 4.21Å; L257-L261 WeakPolarHBondContact O-CG 3.31Å; L257-L261 PolarHBondContact O-N 3.46Å; G258-L261 PolarHBondContact O-N 3.44Å; L261-K263 VanDerWaalsContact C-N 3.31Å; L261-K263 PolarHBondContact O-N 2.98Å; L261-L264 HydrophobicContact CD2-CD1 4.17Å; L261-L264 WeakPolarHBondContact O-CB 3.33Å; L261-L264 PolarHBondContact O-N 3.4Å; L261-D265 VanDerWaalsContact O-CB 3.31Å; L261-D265 WeakPolarHBondContact O-CB 3.48Å; L261-D265 PolarHBondContact O-N 3.08Å
262E88.2Confident85.9Confident126 Ų12641 Ų4159%0.58923%0.225SC*.Hα-helixtrans-58.5-45.1174.2-175.6177.5-167.200111G258 L264 D265 D266G258-E262 WeakPolarHBondContact O-CB 3.34Å; G258-E262 PolarHBondContact O-N 2.9Å; E262-L264 PolarHBondContact O-N 2.8Å; E262-D265 WeakPolarHBondContact O-CB 3.42Å; E262-D265 PolarHBondContact O-N 2.8Å; E262-D266 WeakPolarHBondContact O-CB 3.44Å; E262-D266 PolarHBondContact O-N 3.04Å
263K84.6Confident84.4Confident50 Ų5038.5 Ų38.522%0.21721%0.21CC..Hα-helixtrans-61.9-41.2175178.5178.2-178.4166.20112.9A259 C260 L261 N267 E323A259-K263 WeakPolarHBondContact O-CB 3.31Å; A259-K263 PolarHBondContact O-N 3.1Å; A259-K263 VanDerWaalsContact O-N 3.08Å; C260-K263 WeakPolarHBondContact O-CB 3.41Å; C260-K263 PolarHBondContact O-N 2.96Å; L261-K263 VanDerWaalsContact C-N 3.31Å; L261-K263 PolarHBondContact O-N 2.98Å; K263-N267 PolarHBondContact O-N 3.35Å; K263-N267 PolarHBondContact O-ND2 2.78Å; K263-E323 IonicContact NZ-OE1 3.53Å; K263-E323 PolarHBondContact NZ-OE1 2.87Å; K263-E323 IonicContact NZ-OE2 3.12Å; K263-E323 PolarHBondContact NZ-OE2 3.38Å
264L84Confident82.7Confident21 Ų2141 Ų4111%0.1122%0.221CC..Hα-helixtrans-61.4-51.2173.9-64.2-174.9000108.9C260 L261 E262 D266 N267 I268 F292 A534C260-L264 VanDerWaalsContact O-CG 3.31Å; C260-L264 WeakPolarHBondContact O-CG 3.46Å; C260-L264 PolarHBondContact O-N 3.26Å; L261-L264 HydrophobicContact CD2-CD1 4.17Å; L261-L264 WeakPolarHBondContact O-CB 3.33Å; L261-L264 PolarHBondContact O-N 3.4Å; E262-L264 PolarHBondContact O-N 2.8Å; L264-D266 PolarHBondContact O-N 2.91Å; L264-N267 CarbonylContact O-C 3.52Å; L264-N267 WeakPolarHBondContact O-CA 3.18Å; L264-N267 WeakPolarHBondContact O-CB 3.44Å; L264-N267 PolarHBondContact O-N 3.38Å; L264-I268 VanDerWaalsContact O-CG1 3.27Å; L264-I268 WeakPolarHBondContact O-CG1 3.27Å; L264-I268 PolarHBondContact O-N 3.35Å; L264-F292 HydrophobicContact CD2-CE1 4.02Å; L264-F292 HydrophobicContact CD2-CE2 4.36Å; L264-F292 HydrophobicContact CD2-CZ 3.38Å; L264-A534 HydrophobicContact CD2-CB 3.81Å
265D82.3Confident80.7Confident52 Ų5244.7 Ų44.728%0.27824%0.237SC..Hα-helixtrans-58-44.4-177.7-73-2.9000112.8K227 L261 E262 N267 I268 E269K227-D265 VanDerWaalsContact CD-OD1 3.24Å; K227-D265 WeakPolarHBondContact CD-OD1 3.24Å; K227-D265 VanDerWaalsContact CE-CG 3.44Å; K227-D265 WeakPolarHBondContact CE-OD1 3.46Å; K227-D265 IonicContact NZ-OD1 3.6Å; K227-D265 PolarHBondContact NZ-OD1 3.44Å; K227-D265 IonicContact NZ-OD2 2.72Å; K227-D265 PolarHBondContact NZ-OD2 3.47Å; L261-D265 VanDerWaalsContact O-CB 3.31Å; L261-D265 WeakPolarHBondContact O-CB 3.48Å; L261-D265 PolarHBondContact O-N 3.08Å; E262-D265 WeakPolarHBondContact O-CB 3.42Å; E262-D265 PolarHBondContact O-N 2.8Å; D265-N267 VanDerWaalsContact C-N 3.29Å; D265-N267 PolarHBondContact O-N 2.88Å; D265-I268 WeakPolarHBondContact O-CB 3.42Å; D265-I268 PolarHBondContact O-N 3.33Å; D265-I268 VanDerWaalsContact O-N 3.16Å; D265-E269 VanDerWaalsContact O-CB 3.31Å; D265-E269 WeakPolarHBondContact O-CB 3.34Å; D265-E269 PolarHBondContact O-N 3.42Å
266D81.8Confident78.5Confident77 Ų7739.5 Ų39.541%0.41222%0.223SC..Hα-helixtrans-60.1-39.9175-78.2-20.2000111.8E262 L264 F270E262-D266 WeakPolarHBondContact O-CB 3.44Å; E262-D266 PolarHBondContact O-N 3.04Å; L264-D266 PolarHBondContact O-N 2.91Å; D266-F270 WeakPolarHBondContact O-CB 3.47Å; D266-F270 PolarHBondContact O-N 3.43Å
267N79.2Confident76.9Confident8 Ų844 Ų444%0.04324%0.236CC..Hα-helixtrans-68.8-40.2175.5-84.8-87.3000111.4K263 L264 D265 F270 M271 T288 E289 F292K263-N267 PolarHBondContact O-N 3.35Å; K263-N267 PolarHBondContact O-ND2 2.78Å; L264-N267 CarbonylContact O-C 3.52Å; L264-N267 WeakPolarHBondContact O-CA 3.18Å; L264-N267 WeakPolarHBondContact O-CB 3.44Å; L264-N267 PolarHBondContact O-N 3.38Å; D265-N267 VanDerWaalsContact C-N 3.29Å; D265-N267 PolarHBondContact O-N 2.88Å; N267-F270 PolarHBondContact O-N 2.64Å; N267-M271 VanDerWaalsContact O-CB 3.23Å; N267-M271 WeakPolarHBondContact O-CB 3.47Å; N267-M271 WeakPolarHBondContact O-CG 3.28Å; N267-M271 PolarHBondContact O-N 3.12Å; N267-T288 PolarHBondContact OD1-O 2.96Å; N267-T288 VanDerWaalsContact OD1-O 3.11Å; N267-E289 PolarHBondContact OD1-O 2.96Å; N267-F292 HydrophobicContact CB-CD2 3.5Å; N267-F292 VanDerWaalsContact CB-CD2 3.5Å; N267-F292 HydrophobicContact CB-CE2 3.57Å; N267-F292 HydrophobicContact CB-CG 4.36Å; N267-F292 HydrophobicContact CB-CZ 4.47Å; N267-F292 VanDerWaalsContact CG-CE2 3.43Å; N267-F292 VanDerWaalsContact OD1-CD2 3.32Å; N267-F292 WeakPolarHBondContact OD1-CD2 3.47Å
268I74.9Confident75.5Confident22 Ų2245 Ų4511%0.11324%0.242CC..Hα-helixtrans-62.4-47.9175.7-62.5-177.9000110.5T225 K227 L264 D265 F270 M271 N272T225-I268 HydrophobicContact CG2-CG1 4.3Å; T225-I268 WeakPolarHBondContact OG1-CD1 3.49Å; T225-I268 WeakPolarHBondContact OG1-CG1 3.4Å; K227-I268 HydrophobicContact CG-CD1 4.25Å; L264-I268 VanDerWaalsContact O-CG1 3.27Å; L264-I268 WeakPolarHBondContact O-CG1 3.27Å; L264-I268 PolarHBondContact O-N 3.35Å; D265-I268 WeakPolarHBondContact O-CB 3.42Å; D265-I268 PolarHBondContact O-N 3.33Å; D265-I268 VanDerWaalsContact O-N 3.16Å; I268-F270 VanDerWaalsContact C-N 3.34Å; I268-M271 PolarHBondContact O-N 3.04Å; I268-N272 WeakPolarHBondContact O-CB 3.47Å; I268-N272 PolarHBondContact O-N 3.49Å; I268-N272 PolarHBondContact O-ND2 2.97Å
269E74.4Confident74.7Confident36 Ų3645.1 Ų45.117%0.16824%0.237CC..Hα-helixtrans-59.4-47.1177.9-171.5-174.2154.700110.2L145 K148 Y149 D265 M271 N272 A273L145-E269 HydrophobicContact CD1-CG 4.15Å; L145-E269 HydrophobicContact CD2-CG 3.36Å; L145-E269 WeakPolarHBondContact CD2-OE1 3.36Å; L145-E269 HydrophobicContact CG-CG 4.4Å; K148-E269 WeakPolarHBondContact CD-OE1 3.44Å; K148-E269 IonicContact NZ-OE1 2.78Å; K148-E269 PolarHBondContact NZ-OE1 2.98Å; K148-E269 IonicContact NZ-OE2 3.91Å; K148-E269 PolarHBondContact NZ-OE2 3.29Å; Y149-E269 HydrophobicContact CE2-CG 4.16Å; Y149-E269 PolarHBondContact OH-OE1 3.06Å; D265-E269 VanDerWaalsContact O-CB 3.31Å; D265-E269 WeakPolarHBondContact O-CB 3.34Å; D265-E269 PolarHBondContact O-N 3.42Å; E269-M271 PolarHBondContact O-N 2.92Å; E269-N272 PolarHBondContact O-N 3.4Å; E269-A273 VanDerWaalsContact O-CB 3.27Å; E269-A273 WeakPolarHBondContact O-CB 3.36Å; E269-A273 PolarHBondContact O-N 3.44Å
270F74.6Confident74.4Confident10 Ų1042.7 Ų42.74%0.04422%0.216CC..Hα-helixtrans-58.9-47.7174.4172.7-96.1000111.9Y149 L152 D266 N267 I268 N272 A273 F274 E289 L290Y149-F270 HydrophobicContact CD1-CD2 4.28Å; Y149-F270 HydrophobicContact CE1-CD2 4.44Å; L152-F270 HydrophobicContact CD1-CD2 4.22Å; L152-F270 HydrophobicContact CD1-CE2 3.75Å; D266-F270 WeakPolarHBondContact O-CB 3.47Å; D266-F270 PolarHBondContact O-N 3.43Å; N267-F270 PolarHBondContact O-N 2.64Å; I268-F270 VanDerWaalsContact C-N 3.34Å; F270-N272 PolarHBondContact O-N 2.87Å; F270-A273 CarbonylContact O-C 3.57Å; F270-A273 PolarHBondContact O-N 3.27Å; F270-F274 HydrophobicContact CE1-CB 4.45Å; F270-F274 HydrophobicContact CE1-CD2 4.13Å; F270-F274 HydrophobicContact CE1-CG 4.49Å; F270-F274 HydrophobicContact CE2-CD2 4.25Å; F270-F274 AromaticContact CZ-CD2 3.61Å; F270-F274 HydrophobicContact CZ-CD2 3.61Å; F270-F274 HydrophobicContact CZ-CE2 4.23Å; F270-F274 HydrophobicContact CZ-CG 4.37Å; F270-F274 VanDerWaalsContact O-CB 3.32Å; F270-F274 WeakPolarHBondContact O-CB 3.41Å; F270-F274 PolarHBondContact O-N 2.85Å; F270-E289 WeakPolarHBondContact CD1-O 3.35Å; F270-E289 VanDerWaalsContact CE1-O 3.24Å; F270-E289 WeakPolarHBondContact CE1-O 3.47Å; F270-L290 HydrophobicContact CE1-CD2 3.65Å; F270-L290 HydrophobicContact CZ-CD2 3.76Å
271M71.2Confident74.1Confident27 Ų2743.1 Ų43.113%0.13322%0.219CC..Hα-helixtrans-63-41.3-178.5-79.9-57.1-59.800112.9L221 N267 I268 E269 A273 F274 L293L221-M271 HydrophobicContact CB-CE 4.2Å; L221-M271 HydrophobicContact CD1-CE 4.23Å; N267-M271 VanDerWaalsContact O-CB 3.23Å; N267-M271 WeakPolarHBondContact O-CB 3.47Å; N267-M271 WeakPolarHBondContact O-CG 3.28Å; N267-M271 PolarHBondContact O-N 3.12Å; I268-M271 PolarHBondContact O-N 3.04Å; E269-M271 PolarHBondContact O-N 2.92Å; M271-A273 VanDerWaalsContact C-N 3.34Å; M271-F274 PolarHBondContact O-N 3.42Å; M271-L293 HydrophobicContact CE-CD2 3.39Å; M271-L293 HydrophobicContact SD-CD1 4.29Å; M271-L293 HydrophobicContact SD-CD2 3.33Å; M271-L293 WeakPolarHBondContact SD-CD2 3.45Å; M271-L293 HydrophobicContact SD-CG 4.02Å
272N69.3Low74Confident74 Ų7442.7 Ų42.740%0.39622%0.218SC..Hα-helixtrans-69-33.6175.1-71.6-20.7000111.9N223 I268 E269 F270N223-N272 PolarHBondContact ND2-OD1 3.41Å; I268-N272 WeakPolarHBondContact O-CB 3.47Å; I268-N272 PolarHBondContact O-N 3.49Å; I268-N272 PolarHBondContact O-ND2 2.97Å; E269-N272 PolarHBondContact O-N 3.4Å; F270-N272 PolarHBondContact O-N 2.87Å
273A63.8Low73.8Confident9 Ų942.8 Ų42.87%0.07422%0.222CC..Hα-helixtrans-79.2-17.2177.100000113.9L145 Y149 E269 F270 M271 H275L145-A273 HydrophobicContact CB-CB 3.68Å; L145-A273 HydrophobicContact CD1-CB 4.16Å; L145-A273 HydrophobicContact CG-CB 4.5Å; Y149-A273 HydrophobicContact CD2-CB 3.85Å; Y149-A273 HydrophobicContact CE2-CB 4.27Å; E269-A273 VanDerWaalsContact O-CB 3.27Å; E269-A273 WeakPolarHBondContact O-CB 3.36Å; E269-A273 PolarHBondContact O-N 3.44Å; F270-A273 CarbonylContact O-C 3.57Å; F270-A273 PolarHBondContact O-N 3.27Å; M271-A273 VanDerWaalsContact C-N 3.34Å; A273-H275 PolarHBondContact O-CD2 2.91Å; A273-H275 PolarHBondContact O-N 3.47Å; A273-H275 VanDerWaalsContact O-N 3.09Å
274F62.5Low73.9Confident53 Ų5341.5 Ų41.523%0.23222%0.219CC..  trans-75101.1-172.5-175-95.9000111.1F270 M271 G276 Y277F270-F274 HydrophobicContact CE1-CB 4.45Å; F270-F274 HydrophobicContact CE1-CD2 4.13Å; F270-F274 HydrophobicContact CE1-CG 4.49Å; F270-F274 HydrophobicContact CE2-CD2 4.25Å; F270-F274 AromaticContact CZ-CD2 3.61Å; F270-F274 HydrophobicContact CZ-CD2 3.61Å; F270-F274 HydrophobicContact CZ-CE2 4.23Å; F270-F274 HydrophobicContact CZ-CG 4.37Å; F270-F274 VanDerWaalsContact O-CB 3.32Å; F270-F274 WeakPolarHBondContact O-CB 3.41Å; F270-F274 PolarHBondContact O-N 2.85Å; M271-F274 PolarHBondContact O-N 3.42Å; F274-G276 VanDerWaalsContact CE1-O 3.28Å; F274-G276 WeakPolarHBondContact CE1-O 3.47Å; F274-Y277 WeakPolarHBondContact CE1-O 3.29Å; F274-Y277 VanDerWaalsContact CZ-O 3.28Å; F274-Y277 WeakPolarHBondContact CZ-O 3.37Å
275H52.8Low74.2Confident97 Ų9742.8 Ų42.845%0.44922%0.224SC..  trans-96.712.3172.3-60.3-69.1000113.4E142 R146 A273E142-H275 IonicContact OE2-CE1 3.1Å; E142-H275 PolarHBondContact OE2-CE1 3.5Å; E142-H275 IonicContact OE2-NE2 3.37Å; R146-H275 PolarHBondContact NE-CD2 3.12Å; R146-H275 PolarHBondContact NE-NE2 3.35Å; R146-H275 PolarHBondContact NH2-CE1 3.43Å; R146-H275 PolarHBondContact NH2-NE2 3.46Å; A273-H275 PolarHBondContact O-CD2 2.91Å; A273-H275 PolarHBondContact O-N 3.47Å; A273-H275 VanDerWaalsContact O-N 3.09Å
276G51.6Low74.4Confident40 Ų4044.5 Ų44.541%0.41223%0.233SC..SBendtrans-76.5177.217700000112.5F274 P278F274-G276 VanDerWaalsContact CE1-O 3.28Å; F274-G276 WeakPolarHBondContact CE1-O 3.47Å; G276-P278 WeakPolarHBondContact O-CD 3.29Å
277Y60.4Low74.6Confident122 Ų12242.1 Ų42.148%0.47822%0.224SC..  trans-66.9127.4168.6-67.9-78.8000108.8A194 R195 F274 F279A194-Y277 HydrophobicContact CB-CD1 3.9Å; A194-Y277 HydrophobicContact CB-CE1 4.34Å; R195-Y277 HydrophobicContact CG-CD1 3.66Å; R195-Y277 HydrophobicContact CG-CE1 3.74Å; R195-Y277 HydrophobicContact CG-CG 4.25Å; R195-Y277 VanDerWaalsContact CZ-CD2 3.49Å; F274-Y277 WeakPolarHBondContact CE1-O 3.29Å; F274-Y277 VanDerWaalsContact CZ-O 3.28Å; F274-Y277 WeakPolarHBondContact CZ-O 3.37Å; Y277-F279 PolarHBondContact O-N 2.85Å
278P65.2Low75Confident20 Ų2044.6 Ų44.613%0.1324%0.24CC..SBendtrans-70.864.2-174.921.4-25.7000112.6K220 L221 G276K220-P278 HydrophobicContact CB-CG 4.44Å; K220-P278 HydrophobicContact CG-CG 4.36Å; L221-P278 HydrophobicContact CB-CB 3.85Å; L221-P278 HydrophobicContact CD1-CB 3.26Å; L221-P278 HydrophobicContact CG-CB 3.39Å; G276-P278 WeakPolarHBondContact O-CD 3.29Å
279F75.9Confident75.2Confident23 Ų2348.5 Ų48.510%0.10126%0.257CS..  trans-132.7115.4-174.3-178.5-108.7000111.5E157 E218 Y277 N296 H298 K799E157-F279 VanDerWaalsContact OE1-CD1 3.23Å; E157-F279 WeakPolarHBondContact OE1-CD1 3.47Å; E157-F279 WeakPolarHBondContact OE1-CE1 3.23Å; E218-F279 HydrophobicContact CG-CD2 4.12Å; Y277-F279 PolarHBondContact O-N 2.85Å; F279-N296 HydrophobicContact CE2-CB 4.37Å; F279-N296 WeakPolarHBondContact CE2-OD1 3.33Å; F279-N296 WeakPolarHBondContact CZ-OD1 3.45Å; F279-H298 AromaticContact CD2-CE1 3.82Å; F279-H298 AromaticContact CE2-CE1 3.31Å; F279-H298 WeakPolarHBondContact CE2-CE1 3.28Å; F279-H298 AromaticContact CE2-NE2 3.35Å; F279-H298 WeakPolarHBondContact CE2-NE2 3.49Å; F279-K799 HydrophobicContact CE1-CB 4.16Å; F279-K799 HydrophobicContact CZ-CB 4.23Å; F279-K799 HydrophobicContact CZ-CD 4.43Å
280K85.9Confident75.7Confident3 Ų347.2 Ų47.21%0.01325%0.251CS..BIsolated β-bridgetrans-96.2105.1170.4175.8178.8178.7171.70109.2K285 L290 A291 L293 T295 N296K280-K285 VanDerWaalsContact CE-CA 3.45Å; K280-K285 WeakPolarHBondContact CE-O 3.49Å; K280-K285 PolarHBondContact NZ-O 3.12Å; K280-L290 HydrophobicContact CD-CB 3.96Å; K280-L290 VanDerWaalsContact CD-O 3.3Å; K280-L290 WeakPolarHBondContact CD-O 3.42Å; K280-L290 WeakPolarHBondContact CE-O 3.5Å; K280-L290 HydrophobicContact CG-CB 4.18Å; K280-L290 HydrophobicContact CG-CD1 4.31Å; K280-L290 PolarHBondContact NZ-O 3.47Å; K280-A291 PolarHBondContact NZ-O 2.97Å; K280-L293 HydrophobicContact CB-CB 4Å; K280-L293 HydrophobicContact CB-CD1 4.42Å; K280-L293 HydrophobicContact CD-CB 3.9Å; K280-L293 VanDerWaalsContact CD-O 3.24Å; K280-L293 WeakPolarHBondContact CD-O 3.32Å; K280-L293 PolarHBondContact NZ-O 3.45Å; K280-T295 WeakPolarHBondContact CE-OG1 3.39Å; K280-T295 CarbonylContact O-C 3.52Å; K280-T295 WeakPolarHBondContact O-CA 3.4Å; K280-N296 PolarHBondContact O-N 2.93Å
281S84.9Confident76.3Confident16 Ų1646.8 Ų46.811%0.11225%0.25CC..  trans-69.2160.8176.682.70000111.6L283 S284 K285S281-L283 PolarHBondContact O-N 2.93Å; S281-L283 PolarHBondContact OG-N 3.39Å; S281-S284 PolarHBondContact N-OG 3.28Å; S281-S284 CarbonylContact O-C 3.5Å; S281-S284 PolarHBondContact O-N 2.84Å; S281-S284 VanDerWaalsContact O-N 3.13Å; S281-S284 PolarHBondContact O-OG 2.86Å; S281-S284 PolarHBondContact OG-N 3.48Å; S281-S284 PolarHBondContact OG-OG 3.32Å; S281-K285 PolarHBondContact O-N 3.38Å
282S86.9Confident77.1Confident11 Ų1145.7 Ų45.78%0.07724%0.244CC..THydrogen-bonded Turntrans-66.1-17.1174.865.30000114.2K285 N800S282-K285 WeakPolarHBondContact O-CD 3.17Å; S282-K285 WeakPolarHBondContact O-CG 3.4Å; S282-N800 WeakPolarHBondContact CA-OD1 3.44Å; S282-N800 WeakPolarHBondContact CB-OD1 3.15Å; S282-N800 PolarHBondContact N-OD1 3.16Å; S282-N800 PolarHBondContact OG-OD1 3.17Å
283L84.6Confident78Confident128 Ų12842.3 Ų42.367%0.6723%0.226SC*.THydrogen-bonded Turntrans-76.4-30.8173.1-64.9176.9000111.7S281 N800S281-L283 PolarHBondContact O-N 2.93Å; S281-L283 PolarHBondContact OG-N 3.39Å; L283-N800 WeakPolarHBondContact CD1-O 3.46Å; L283-N800 WeakPolarHBondContact CG-O 3.45Å
284S85.9Confident79.3Confident23 Ų2342 Ų4216%0.16122%0.224CC..SBendtrans-100.716.1177.663.90000112.9S281 D286 A287 L290S281-S284 PolarHBondContact N-OG 3.28Å; S281-S284 CarbonylContact O-C 3.5Å; S281-S284 PolarHBondContact O-N 2.84Å; S281-S284 VanDerWaalsContact O-N 3.13Å; S281-S284 PolarHBondContact O-OG 2.86Å; S281-S284 PolarHBondContact OG-N 3.48Å; S281-S284 PolarHBondContact OG-OG 3.32Å; S284-D286 PolarHBondContact O-N 3.05Å; S284-A287 WeakPolarHBondContact O-CB 3.39Å; S284-A287 PolarHBondContact O-N 2.76Å; S284-L290 WeakPolarHBondContact OG-CD1 3.43Å
285K89.2Confident80.8Confident47 Ų4739.5 Ų39.520%0.20421%0.213CC..THydrogen-bonded Turntrans-59.3-34-176.872.7-170.5176-154.90112.8K280 S281 S282 A287 T295 Y321K280-K285 VanDerWaalsContact CE-CA 3.45Å; K280-K285 WeakPolarHBondContact CE-O 3.49Å; K280-K285 PolarHBondContact NZ-O 3.12Å; S281-K285 PolarHBondContact O-N 3.38Å; S282-K285 WeakPolarHBondContact O-CD 3.17Å; S282-K285 WeakPolarHBondContact O-CG 3.4Å; K285-A287 VanDerWaalsContact C-N 3.34Å; K285-T295 HydrophobicContact CB-CG2 3.98Å; K285-Y321 HydrophobicContact CB-CD1 4.32Å; K285-Y321 HydrophobicContact CB-CD2 4.31Å; K285-Y321 HydrophobicContact CB-CG 4.21Å; K285-Y321 HydrophobicContact CD-CD1 3.95Å; K285-Y321 HydrophobicContact CD-CE1 3.99Å; K285-Y321 HydrophobicContact CG-CD1 4.01Å; K285-Y321 HydrophobicContact CG-CE1 4.41Å; K285-Y321 HydrophobicContact CG-CG 4.23Å; K285-Y321 VanDerWaalsContact O-CB 3.22Å; K285-Y321 WeakPolarHBondContact O-CB 3.27Å
286D87.6Confident82.7Confident89 Ų8934.9 Ų34.948%0.47619%0.191SC..THydrogen-bonded Turntrans-87.5-1.5-179-51.6-55.5000112.4S284 T288 Y321S284-D286 PolarHBondContact O-N 3.05Å; D286-T288 PolarHBondContact O-N 2.94Å; D286-Y321 WeakPolarHBondContact OD1-CB 3.24Å
287A86.3Confident84.7Confident26 Ų2633.4 Ų33.422%0.21517%0.174CC..  trans-70.4122.4179.200000111S284 K285 E289 L290 A291S284-A287 WeakPolarHBondContact O-CB 3.39Å; S284-A287 PolarHBondContact O-N 2.76Å; K285-A287 VanDerWaalsContact C-N 3.34Å; A287-E289 VanDerWaalsContact C-N 3.3Å; A287-E289 PolarHBondContact O-N 2.71Å; A287-L290 HydrophobicContact CB-CB 4.41Å; A287-L290 HydrophobicContact CB-CD1 4.37Å; A287-L290 HydrophobicContact CB-CG 4.37Å; A287-L290 CarbonylContact O-C 3.32Å; A287-L290 PolarHBondContact O-N 3.04Å; A287-L290 VanDerWaalsContact O-N 3.16Å; A287-A291 PolarHBondContact O-N 3.31Å
288T86.4Confident86.3Confident61 Ų6127.6 Ų27.637%0.37415%0.151SC..G310 helixtrans-62.8-36-176.4-53.70000112.2N267 D286 L290 A291N267-T288 PolarHBondContact OD1-O 2.96Å; N267-T288 VanDerWaalsContact OD1-O 3.11Å; D286-T288 PolarHBondContact O-N 2.94Å; T288-L290 PolarHBondContact O-N 3.35Å; T288-A291 WeakPolarHBondContact O-CB 3.49Å; T288-A291 PolarHBondContact O-N 3.37Å; T288-A291 VanDerWaalsContact O-N 3.15Å
289E80.3Confident87.7Confident103 Ų10326.8 Ų26.848%0.48115%0.146SC..G310 helixtrans-69.4-21.9-180-50.883.717400112.3N267 F270 A287N267-E289 PolarHBondContact OD1-O 2.96Å; F270-E289 WeakPolarHBondContact CD1-O 3.35Å; F270-E289 VanDerWaalsContact CE1-O 3.24Å; F270-E289 WeakPolarHBondContact CE1-O 3.47Å; A287-E289 VanDerWaalsContact C-N 3.3Å; A287-E289 PolarHBondContact O-N 2.71Å
290L83.4Confident88.5Confident9 Ų925.7 Ų25.75%0.04714%0.141CC..G310 helixtrans-104.711.6176.9-53.9178.4000111.3F270 K280 S284 A287 T288 F292 L293F270-L290 HydrophobicContact CE1-CD2 3.65Å; F270-L290 HydrophobicContact CZ-CD2 3.76Å; K280-L290 HydrophobicContact CD-CB 3.96Å; K280-L290 VanDerWaalsContact CD-O 3.3Å; K280-L290 WeakPolarHBondContact CD-O 3.42Å; K280-L290 WeakPolarHBondContact CE-O 3.5Å; K280-L290 HydrophobicContact CG-CB 4.18Å; K280-L290 HydrophobicContact CG-CD1 4.31Å; K280-L290 PolarHBondContact NZ-O 3.47Å; S284-L290 WeakPolarHBondContact OG-CD1 3.43Å; A287-L290 HydrophobicContact CB-CB 4.41Å; A287-L290 HydrophobicContact CB-CD1 4.37Å; A287-L290 HydrophobicContact CB-CG 4.37Å; A287-L290 CarbonylContact O-C 3.32Å; A287-L290 PolarHBondContact O-N 3.04Å; A287-L290 VanDerWaalsContact O-N 3.16Å; T288-L290 PolarHBondContact O-N 3.35Å; L290-F292 VanDerWaalsContact C-N 3.25Å; L290-F292 PolarHBondContact O-N 3.48Å; L290-L293 HydrophobicContact CB-CD1 4.24Å; L290-L293 HydrophobicContact CD2-CD1 3.78Å; L290-L293 WeakPolarHBondContact O-CB 3.34Å; L290-L293 PolarHBondContact O-N 2.89Å; L290-L293 VanDerWaalsContact O-N 3.07Å
291A88Confident88.8Confident1 Ų126 Ų261%0.00814%0.143CC..THydrogen-bonded Turntrans-56.3-40.5-171.200000112.1K280 A287 T288 L293 I535 Q539K280-A291 PolarHBondContact NZ-O 2.97Å; A287-A291 PolarHBondContact O-N 3.31Å; T288-A291 WeakPolarHBondContact O-CB 3.49Å; T288-A291 PolarHBondContact O-N 3.37Å; T288-A291 VanDerWaalsContact O-N 3.15Å; A291-L293 PolarHBondContact O-N 3.37Å; A291-I535 HydrophobicContact CB-CD1 4.04Å; A291-I535 HydrophobicContact CB-CG1 4.2Å; A291-I535 HydrophobicContact CB-CG2 4.44Å; A291-I535 VanDerWaalsContact O-CG2 3.25Å; A291-I535 WeakPolarHBondContact O-CG2 3.21Å; A291-Q539 PolarHBondContact O-NE2 3.17Å
292F88.3Confident89.2Confident5 Ų525.2 Ų25.22%0.02214%0.138CC..THydrogen-bonded Turntrans-73.6-10.9-176.8-72.8-99.9000114.5T225 L264 N267 L290 A534 I535 S538T225-F292 HydrophobicContact CG2-CD1 3.73Å; T225-F292 HydrophobicContact CG2-CE1 3.9Å; L264-F292 HydrophobicContact CD2-CE1 4.02Å; L264-F292 HydrophobicContact CD2-CE2 4.36Å; L264-F292 HydrophobicContact CD2-CZ 3.38Å; N267-F292 HydrophobicContact CB-CD2 3.5Å; N267-F292 VanDerWaalsContact CB-CD2 3.5Å; N267-F292 HydrophobicContact CB-CE2 3.57Å; N267-F292 HydrophobicContact CB-CG 4.36Å; N267-F292 HydrophobicContact CB-CZ 4.47Å; N267-F292 VanDerWaalsContact CG-CE2 3.43Å; N267-F292 VanDerWaalsContact OD1-CD2 3.32Å; N267-F292 WeakPolarHBondContact OD1-CD2 3.47Å; L290-F292 VanDerWaalsContact C-N 3.25Å; L290-F292 PolarHBondContact O-N 3.48Å; F292-A534 HydrophobicContact CE1-CB 4Å; F292-A534 HydrophobicContact CZ-CB 4.37Å; F292-I535 HydrophobicContact CD2-CG1 4.14Å; F292-I535 HydrophobicContact CE1-CG1 4.06Å; F292-I535 HydrophobicContact CE2-CD1 4.44Å; F292-I535 HydrophobicContact CE2-CG1 3.62Å; F292-I535 HydrophobicContact CZ-CG1 3.53Å; F292-S538 PolarHBondContact O-OG 3.09Å
293L87.3Confident89.3Confident3 Ų325.8 Ų25.82%0.01614%0.138CC..SBendtrans-88.8136.9-178.5-53-173.3000111.2L221 M271 K280 L290 A291 T295L221-L293 HydrophobicContact CD1-CD1 3.7Å; L221-L293 HydrophobicContact CD1-CD2 3.28Å; L221-L293 HydrophobicContact CD1-CG 4Å; L221-L293 HydrophobicContact CD2-CD2 3.78Å; L221-L293 HydrophobicContact CG-CD2 4.06Å; M271-L293 HydrophobicContact CE-CD2 3.39Å; M271-L293 HydrophobicContact SD-CD1 4.29Å; M271-L293 HydrophobicContact SD-CD2 3.33Å; M271-L293 WeakPolarHBondContact SD-CD2 3.45Å; M271-L293 HydrophobicContact SD-CG 4.02Å; K280-L293 HydrophobicContact CB-CB 4Å; K280-L293 HydrophobicContact CB-CD1 4.42Å; K280-L293 HydrophobicContact CD-CB 3.9Å; K280-L293 VanDerWaalsContact CD-O 3.24Å; K280-L293 WeakPolarHBondContact CD-O 3.32Å; K280-L293 PolarHBondContact NZ-O 3.45Å; L290-L293 HydrophobicContact CB-CD1 4.24Å; L290-L293 HydrophobicContact CD2-CD1 3.78Å; L290-L293 WeakPolarHBondContact O-CB 3.34Å; L290-L293 PolarHBondContact O-N 2.89Å; L290-L293 VanDerWaalsContact O-N 3.07Å; A291-L293 PolarHBondContact O-N 3.37Å; L293-T295 PolarHBondContact O-N 2.93Å
294P92.7Very high89.3Confident3 Ų320.1 Ų20.12%0.01911%0.109CC..PPolyproline II helixtrans-65.4130167.81.69000109.2N296 L297 Q539 T542P294-N296 PolarHBondContact O-N 3.34Å; P294-L297 HydrophobicContact CB-CB 4.12Å; P294-L297 HydrophobicContact CG-CB 4.3Å; P294-L297 HydrophobicContact CG-CD2 4.04Å; P294-Q539 HydrophobicContact CB-CB 4.2Å; P294-Q539 HydrophobicContact CG-CB 4.27Å; P294-T542 HydrophobicContact CG-CG2 4.32Å
295T93.1Very high88.9Confident0 Ų022.5 Ų22.50%013%0.126CC..BIsolated β-bridgetrans-67.6131.9176.3-56.40000109.3K280 K285 L293 L297 C315 G316K280-T295 WeakPolarHBondContact CE-OG1 3.39Å; K280-T295 CarbonylContact O-C 3.52Å; K280-T295 WeakPolarHBondContact O-CA 3.4Å; K285-T295 HydrophobicContact CB-CG2 3.98Å; L293-T295 PolarHBondContact O-N 2.93Å; T295-L297 VanDerWaalsContact C-N 3.29Å; T295-L297 PolarHBondContact O-N 3.46Å; T295-C315 CarbonylContact O-C 3.51Å; T295-G316 PolarHBondContact O-N 2.86Å
296N92.6Very high88.1Confident0 Ų024.2 Ų24.20%014%0.137CC..THydrogen-bonded Turntrans5140.6175.9-72.4-32.8000114.7F279 K280 P294 H298 S752 N800F279-N296 HydrophobicContact CE2-CB 4.37Å; F279-N296 WeakPolarHBondContact CE2-OD1 3.33Å; F279-N296 WeakPolarHBondContact CZ-OD1 3.45Å; K280-N296 PolarHBondContact O-N 2.93Å; P294-N296 PolarHBondContact O-N 3.34Å; N296-H298 PolarHBondContact O-CD2 3.47Å; N296-H298 PolarHBondContact O-N 2.91Å; N296-S752 WeakPolarHBondContact CB-O 3.29Å; N296-S752 PolarHBondContact ND2-O 3.06Å; N296-N800 PolarHBondContact ND2-ND2 2.98Å; N296-N800 PolarHBondContact ND2-OD1 3.25Å; N296-N800 PolarHBondContact OD1-ND2 3.35Å; N296-N800 PolarHBondContact OD1-OD1 3.24Å; N296-N800 VanDerWaalsContact OD1-OD1 3.13Å
297L93.9Very high87.1Confident8 Ų829 Ų294%0.04215%0.154CC..  trans-68.1124.9174.1-177.161.7000110.4P219 P294 T295 T314 C315 T542P219-L297 HydrophobicContact CB-CD2 4.05Å; P219-L297 HydrophobicContact CG-CD2 3.92Å; P219-L297 HydrophobicContact CG-CG 3.89Å; P294-L297 HydrophobicContact CB-CB 4.12Å; P294-L297 HydrophobicContact CG-CB 4.3Å; P294-L297 HydrophobicContact CG-CD2 4.04Å; T295-L297 VanDerWaalsContact C-N 3.29Å; T295-L297 PolarHBondContact O-N 3.46Å; L297-T314 CarbonylContact C-O 3.47Å; L297-T314 VanDerWaalsContact CA-O 3.28Å; L297-T314 WeakPolarHBondContact CA-O 3.45Å; L297-C315 HydrophobicContact CB-CB 4.49Å; L297-C315 HydrophobicContact CD1-CB 3.97Å; L297-T542 HydrophobicContact CD2-CG2 4.35Å
298H93.8Very high86.8Confident0 Ų030 Ų300%016%0.158CC..EExtended strand (participates in β ladder)trans-141.7151.5175.6-63.5-64.8000111.3M216 A217 F279 N296 F313 T314 N796M216-H298 HydrophobicContact CG-CB 4.2Å; M216-H298 HydrophobicContact SD-CB 4.5Å; A217-H298 CarbonylContact O-C 3.6Å; A217-H298 VanDerWaalsContact O-CA 3.25Å; A217-H298 WeakPolarHBondContact O-CA 3.23Å; F279-H298 AromaticContact CD2-CE1 3.82Å; F279-H298 AromaticContact CE2-CE1 3.31Å; F279-H298 WeakPolarHBondContact CE2-CE1 3.28Å; F279-H298 AromaticContact CE2-NE2 3.35Å; F279-H298 WeakPolarHBondContact CE2-NE2 3.49Å; N296-H298 PolarHBondContact O-CD2 3.47Å; N296-H298 PolarHBondContact O-N 2.91Å; H298-F313 CarbonylContact O-C 3.57Å; H298-F313 VanDerWaalsContact O-CA 3.31Å; H298-F313 WeakPolarHBondContact O-CA 3.46Å; H298-T314 PolarHBondContact N-O 3.22Å; H298-T314 PolarHBondContact O-N 2.92Å; H298-N796 PolarHBondContact NE2-OD1 2.95Å
299V94.2Very high86.9Confident4 Ų428.9 Ų28.92%0.02415%0.149CC..EExtended strand (participates in β ladder)trans-94.8134.2156.262.90000108.1F193 M216 A217 Y312 F313F193-V299 HydrophobicContact CD1-CB 4.47Å; F193-V299 HydrophobicContact CD1-CG1 3.57Å; F193-V299 HydrophobicContact CD2-CG1 4.47Å; F193-V299 HydrophobicContact CE1-CB 4.08Å; F193-V299 HydrophobicContact CE1-CG1 3.58Å; F193-V299 HydrophobicContact CE2-CG1 4.45Å; F193-V299 HydrophobicContact CG-CG1 4.08Å; F193-V299 HydrophobicContact CZ-CG1 4.04Å; M216-V299 VanDerWaalsContact CA-O 3.29Å; M216-V299 WeakPolarHBondContact CA-O 3.39Å; A217-V299 HydrophobicContact CB-CG1 3.82Å; A217-V299 PolarHBondContact N-O 3.21Å; A217-V299 PolarHBondContact O-N 2.87Å; V299-Y312 CarbonylContact C-O 3.6Å; V299-Y312 WeakPolarHBondContact CA-O 3.4Å; V299-F313 HydrophobicContact CB-CD1 4.33Å; V299-F313 HydrophobicContact CB-CE1 3.85Å; V299-F313 HydrophobicContact CB-CZ 3.96Å; V299-F313 HydrophobicContact CG2-CE1 4.13Å; V299-F313 HydrophobicContact CG2-CE2 3.97Å; V299-F313 HydrophobicContact CG2-CZ 3.72Å
300Q93.7Very high87.5Confident0 Ų024.3 Ų24.30%013%0.127CC..EExtended strand (participates in β ladder)trans-117.1129.3168.1-75.675.133.300108.6H215 M216 D311 Y312 T314 V761H215-Q300 CarbonylContact O-C 3.59Å; H215-Q300 VanDerWaalsContact O-CA 3.24Å; H215-Q300 WeakPolarHBondContact O-CA 3.29Å; M216-Q300 HydrophobicContact CB-CG 4.33Å; M216-Q300 HydrophobicContact CG-CG 4.23Å; M216-Q300 VanDerWaalsContact CG-NE2 3.32Å; M216-Q300 PolarHBondContact SD-NE2 2.88Å; Q300-D311 CarbonylContact O-C 3.5Å; Q300-D311 WeakPolarHBondContact O-CA 3.35Å; Q300-Y312 HydrophobicContact CB-CD2 4.34Å; Q300-Y312 PolarHBondContact N-O 3.3Å; Q300-Y312 PolarHBondContact O-N 3.06Å; Q300-T314 PolarHBondContact NE2-OG1 3.4Å; Q300-T314 VanDerWaalsContact OE1-CG2 3.27Å; Q300-T314 PolarHBondContact OE1-OG1 3.26Å; Q300-V761 HydrophobicContact CB-CG1 4.49Å; Q300-V761 HydrophobicContact CG-CG1 4.5Å
301S92.2Very high88Confident8 Ų824.9 Ų24.96%0.05613%0.131CC..EExtended strand (participates in β ladder)trans-129.8123.8-178.9-56.90000110.3E214 H215 M310 D311E214-S301 CarbonylContact C-O 3.55Å; H215-S301 PolarHBondContact N-O 2.91Å; H215-S301 PolarHBondContact ND1-O 3.37Å; H215-S301 PolarHBondContact O-N 2.92Å; S301-M310 CarbonylContact C-O 3.55Å; S301-M310 WeakPolarHBondContact CA-O 3.48Å; S301-D311 WeakPolarHBondContact CB-OD1 3.41Å; S301-D311 PolarHBondContact OG-OD1 3.09Å
302V92.2Very high88.4Confident0 Ų024.9 Ų24.90%013%0.13CC..EExtended strand (participates in β ladder)trans-102.3128.5171.6173.80000109.1L212 C213 E214 K309 M310 E765L212-V302 HydrophobicContact CD1-CG1 3.16Å; L212-V302 HydrophobicContact CD2-CG1 4.14Å; L212-V302 HydrophobicContact CG-CG1 3.7Å; C213-V302 WeakPolarHBondContact O-CA 3.22Å; E214-V302 HydrophobicContact CG-CG2 4.23Å; V302-K309 CarbonylContact O-C 3.55Å; V302-K309 WeakPolarHBondContact O-CA 3.35Å; V302-M310 PolarHBondContact N-O 3.22Å; V302-M310 PolarHBondContact O-N 3.44Å; V302-E765 HydrophobicContact CG2-CB 4.31Å; V302-E765 HydrophobicContact CG2-CG 3.57Å; V302-E765 WeakPolarHBondContact CG2-OE1 3.37Å
303R89Confident88.8Confident24 Ų2424.7 Ų24.79%0.09113%0.129CC..EExtended strand (participates in β ladder)trans-125.5129.3177.7-65.2-174.2-167.3145.84.2110.7L212 C213 C308 K309L212-R303 CarbonylContact C-O 3.6Å; C213-R303 PolarHBondContact N-O 3.01Å; C213-R303 PolarHBondContact O-N 3.43Å; R303-C308 WeakPolarHBondContact CA-O 3.48Å; R303-K309 HydrophobicContact CG-CB 4.13Å; R303-K309 HydrophobicContact CG-CD 4.34Å; R303-K309 HydrophobicContact CG-CG 3.86Å
304C86.3Confident89.3Confident8 Ų824.5 Ų24.55%0.05413%0.129CC..EExtended strand (participates in β ladder)trans-91.6152.7170.3-630000110.9V210 L212 D306 K307 C308 L772 Y773V210-C304 HydrophobicContact CG1-CB 4.46Å; L212-C304 VanDerWaalsContact CD1-SG 3.54Å; C304-D306 WeakPolarHBondContact CB-OD1 3.43Å; C304-D306 PolarHBondContact O-N 3.19Å; C304-D306 VanDerWaalsContact O-N 3.11Å; C304-K307 PolarHBondContact O-N 2.69Å; C304-K307 VanDerWaalsContact O-N 3.12Å; C304-C308 HydrophobicContact CB-CB 4.41Å; C304-C308 PolarHBondContact N-O 3.07Å; C304-L772 HydrophobicContact CB-CD2 4.43Å; C304-Y773 WeakPolarHBondContact CB-OH 3.26Å; C304-Y773 PolarHBondContact SG-OH 3.29Å; C304-Y773 VanDerWaalsContact SG-OH 3.37Å
305S77.5Confident89.5Confident74 Ų7424.4 Ų24.452%0.51713%0.128SC..THydrogen-bonded Turntrans-59-20.6179.149.70000114.8V211V211-S305 PolarHBondContact N-OG 3.33Å; V211-S305 PolarHBondContact O-N 3.42Å
306D71.2Confident89.7Confident82 Ų8224.4 Ų24.444%0.43913%0.128SC..THydrogen-bonded Turntrans-93.717.1178.863.8-6.4000114.2C304 Y773C304-D306 WeakPolarHBondContact CB-OD1 3.43Å; C304-D306 PolarHBondContact O-N 3.19Å; C304-D306 VanDerWaalsContact O-N 3.11Å; D306-Y773 PolarHBondContact OD1-OH 3.27Å; D306-Y773 WeakPolarHBondContact OD2-CE1 3.5Å; D306-Y773 PolarHBondContact OD2-OH 3.36Å
307K67.1Low89.9Confident190 Ų19024.4 Ų24.483%0.82613%0.128SC*.SBendtrans82.6-1.6174.7-55.7-173.8176.9-176.50117.5C304 K309C304-K307 PolarHBondContact O-N 2.69Å; C304-K307 VanDerWaalsContact O-N 3.12Å; K307-K309 PolarHBondContact O-N 3.07Å
308C80.8Confident90.1Very high46 Ų4624.1 Ų24.131%0.31113%0.126SC..  trans-68.9123.4172.7-70.20000111.2R303 C304 F768 L772R303-C308 WeakPolarHBondContact CA-O 3.48Å; C304-C308 HydrophobicContact CB-CB 4.41Å; C304-C308 PolarHBondContact N-O 3.07Å; C308-F768 HydrophobicContact CB-CZ 4.23Å; C308-L772 HydrophobicContact CB-CD1 4.45Å; C308-L772 HydrophobicContact CB-CD2 3.6Å
309K87.6Confident90.2Very high39 Ų3924.1 Ų24.117%0.1713%0.126CC..EExtended strand (participates in β ladder)trans-120140.6179178.3-177.8176.4-144.80110.4V302 R303 K307 D311 M554V302-K309 CarbonylContact O-C 3.55Å; V302-K309 WeakPolarHBondContact O-CA 3.35Å; R303-K309 HydrophobicContact CG-CB 4.13Å; R303-K309 HydrophobicContact CG-CD 4.34Å; R303-K309 HydrophobicContact CG-CG 3.86Å; K307-K309 PolarHBondContact O-N 3.07Å; K309-D311 WeakPolarHBondContact CE-OD1 3.42Å; K309-D311 WeakPolarHBondContact CE-OD2 3.34Å; K309-D311 IonicContact NZ-OD1 3.19Å; K309-D311 IonicContact NZ-OD2 3.27Å; K309-D311 PolarHBondContact NZ-OD2 3.26Å; K309-M554 PolarHBondContact NZ-O 3.28Å
310M92.1Very high90.2Very high7 Ų723.9 Ų23.93%0.03413%0.125CC..EExtended strand (participates in β ladder)trans-137.1128.7173.1-175.6172.457.500110.8S301 V302 Y312 R740 E765 F768S301-M310 CarbonylContact C-O 3.55Å; S301-M310 WeakPolarHBondContact CA-O 3.48Å; V302-M310 PolarHBondContact N-O 3.22Å; V302-M310 PolarHBondContact O-N 3.44Å; M310-Y312 HydrophobicContact CE-CE2 3.68Å; M310-Y312 WeakPolarHBondContact CE-OH 3.29Å; M310-Y312 HydrophobicContact CG-CE2 4.19Å; M310-Y312 HydrophobicContact SD-CE2 4.39Å; M310-R740 PolarHBondContact SD-NH1 3.16Å; M310-E765 HydrophobicContact CE-CG 4.47Å; M310-F768 HydrophobicContact CB-CD1 4.43Å; M310-F768 HydrophobicContact CB-CE1 4.14Å; M310-F768 HydrophobicContact CB-CE2 4.33Å; M310-F768 HydrophobicContact CB-CZ 4.09Å; M310-F768 HydrophobicContact CE-CB 3.24Å; M310-F768 HydrophobicContact CE-CD1 3.45Å; M310-F768 VanDerWaalsContact CE-CD1 3.45Å; M310-F768 HydrophobicContact CE-CD2 3.88Å; M310-F768 HydrophobicContact CE-CE1 4.21Å; M310-F768 HydrophobicContact CE-CG 3.24Å; M310-F768 HydrophobicContact SD-CB 3.83Å; M310-F768 HydrophobicContact SD-CD1 4.21Å; M310-F768 HydrophobicContact SD-CD2 3.56Å; M310-F768 VanDerWaalsContact SD-CD2 3.56Å; M310-F768 HydrophobicContact SD-CE2 4.12Å; M310-F768 HydrophobicContact SD-CG 3.6Å; M310-F768 VanDerWaalsContact SD-CG 3.6Å
311D94.9Very high90.2Very high21 Ų2124.4 Ų24.411%0.11213%0.127CC..EExtended strand (participates in β ladder)trans-107.5147.9-179.1-66.8-30.5000111.7Q300 S301 K309 N550Q300-D311 CarbonylContact O-C 3.5Å; Q300-D311 WeakPolarHBondContact O-CA 3.35Å; S301-D311 WeakPolarHBondContact CB-OD1 3.41Å; S301-D311 PolarHBondContact OG-OD1 3.09Å; K309-D311 WeakPolarHBondContact CE-OD1 3.42Å; K309-D311 WeakPolarHBondContact CE-OD2 3.34Å; K309-D311 IonicContact NZ-OD1 3.19Å; K309-D311 IonicContact NZ-OD2 3.27Å; K309-D311 PolarHBondContact NZ-OD2 3.26Å; D311-N550 PolarHBondContact OD2-ND2 3.48Å
312Y95.9Very high90.2Very high0 Ų025.6 Ų25.60%014%0.135CC..EExtended strand (participates in β ladder)trans-133.2149.1169.8-54.7-101.7000108.9V299 Q300 M310 V746 I748 V761 D764 E765V299-Y312 CarbonylContact C-O 3.6Å; V299-Y312 WeakPolarHBondContact CA-O 3.4Å; Q300-Y312 HydrophobicContact CB-CD2 4.34Å; Q300-Y312 PolarHBondContact N-O 3.3Å; Q300-Y312 PolarHBondContact O-N 3.06Å; M310-Y312 HydrophobicContact CE-CE2 3.68Å; M310-Y312 WeakPolarHBondContact CE-OH 3.29Å; M310-Y312 HydrophobicContact CG-CE2 4.19Å; M310-Y312 HydrophobicContact SD-CE2 4.39Å; Y312-V746 HydrophobicContact CD1-CG1 4.39Å; Y312-I748 HydrophobicContact CD1-CD1 3.87Å; Y312-I748 HydrophobicContact CE1-CD1 4.34Å; Y312-V761 HydrophobicContact CD1-CG2 4.29Å; Y312-V761 HydrophobicContact CD2-CG1 4.35Å; Y312-V761 HydrophobicContact CE2-CG1 4.45Å; Y312-V761 HydrophobicContact CG-CG2 4.41Å; Y312-D764 HydrophobicContact CE1-CB 3.95Å; Y312-D764 WeakPolarHBondContact CE1-OD2 3.14Å; Y312-D764 VanDerWaalsContact OH-C 3.25Å; Y312-D764 WeakPolarHBondContact OH-CB 3.39Å; Y312-D764 PolarHBondContact OH-OD2 3.09Å; Y312-E765 HydrophobicContact CE2-CG 3.61Å; Y312-E765 PolarHBondContact OH-N 3.13Å; Y312-E765 VanDerWaalsContact OH-N 3.12Å
313F97.5Very high90.2Very high1 Ų128 Ų280%0.00415%0.146CC..EExtended strand (participates in β ladder)trans-111.2133.7162.1-75.9-99.5000108.6P219 H298 V299 S546 V547 N550 V746 V747 I748P219-F313 HydrophobicContact CG-CE1 4.18Å; H298-F313 CarbonylContact O-C 3.57Å; H298-F313 VanDerWaalsContact O-CA 3.31Å; H298-F313 WeakPolarHBondContact O-CA 3.46Å; V299-F313 HydrophobicContact CB-CD1 4.33Å; V299-F313 HydrophobicContact CB-CE1 3.85Å; V299-F313 HydrophobicContact CB-CZ 3.96Å; V299-F313 HydrophobicContact CG2-CE1 4.13Å; V299-F313 HydrophobicContact CG2-CE2 3.97Å; V299-F313 HydrophobicContact CG2-CZ 3.72Å; F313-S546 WeakPolarHBondContact CZ-O 3.27Å; F313-V547 HydrophobicContact CB-CG2 4.11Å; F313-V547 HydrophobicContact CD1-CG2 4.03Å; F313-V547 HydrophobicContact CD2-CB 4.28Å; F313-V547 HydrophobicContact CD2-CG2 3.46Å; F313-V547 VanDerWaalsContact CD2-CG2 3.46Å; F313-V547 HydrophobicContact CE1-CG2 4.36Å; F313-V547 HydrophobicContact CE2-CB 4.19Å; F313-V547 HydrophobicContact CE2-CG1 4.49Å; F313-V547 HydrophobicContact CE2-CG2 3.85Å; F313-V547 HydrophobicContact CG-CG2 3.56Å; F313-V547 HydrophobicContact CZ-CG2 4.28Å; F313-N550 HydrophobicContact CE2-CB 4.08Å; F313-N550 HydrophobicContact CZ-CB 3.6Å; F313-V746 PolarHBondContact N-O 3.14Å; F313-V747 HydrophobicContact CB-CB 4.45Å; F313-V747 HydrophobicContact CB-CG1 4.4Å; F313-V747 HydrophobicContact CB-CG2 4.03Å; F313-V747 CarbonylContact O-C 3.57Å; F313-V747 WeakPolarHBondContact O-CA 3.37Å; F313-I748 PolarHBondContact O-N 3.41Å
314T97.5Very high90.4Very high0 Ų028 Ų280%015%0.154CC..EExtended strand (participates in β ladder)trans-123.2141.8174.856.80000111.2L297 H298 Q300 I748 V761 R793L297-T314 CarbonylContact C-O 3.47Å; L297-T314 VanDerWaalsContact CA-O 3.28Å; L297-T314 WeakPolarHBondContact CA-O 3.45Å; H298-T314 PolarHBondContact N-O 3.22Å; H298-T314 PolarHBondContact O-N 2.92Å; Q300-T314 PolarHBondContact NE2-OG1 3.4Å; Q300-T314 VanDerWaalsContact OE1-CG2 3.27Å; Q300-T314 PolarHBondContact OE1-OG1 3.26Å; T314-I748 VanDerWaalsContact CA-O 3.28Å; T314-I748 WeakPolarHBondContact CA-O 3.49Å; T314-I748 HydrophobicContact CG2-CB 4.22Å; T314-V761 HydrophobicContact CG2-CG2 3.47Å; T314-V761 VanDerWaalsContact CG2-CG2 3.47Å; T314-R793 PolarHBondContact OG1-NH1 2.98Å
315C96.7Very high90.7Very high0 Ų029.2 Ų29.20%016%0.158CC..EExtended strand (participates in β ladder)trans-157.3170.1176.862.60000112.3T295 L297 F318 I748 C749 C750 G753T295-C315 CarbonylContact O-C 3.51Å; L297-C315 HydrophobicContact CB-CB 4.49Å; L297-C315 HydrophobicContact CD1-CB 3.97Å; C315-F318 WeakPolarHBondContact SG-CE1 3.46Å; C315-I748 PolarHBondContact N-O 2.76Å; C315-I748 VanDerWaalsContact N-O 3.08Å; C315-C749 WeakPolarHBondContact O-CA 3.38Å; C315-C749 WeakPolarHBondContact O-CB 3.42Å; C315-C750 PolarHBondContact O-N 2.91Å; C315-G753 WeakPolarHBondContact O-CA 3.14Å
316G96.7Very high91.3Very high0 Ų032.7 Ų32.70%017%0.171CC..EExtended strand (participates in β ladder)trans-65.116516100000111T295 C750T295-G316 PolarHBondContact O-N 2.86Å; G316-C750 CarbonylContact C-O 3.32Å; G316-C750 VanDerWaalsContact CA-O 3.28Å; G316-C750 WeakPolarHBondContact CA-O 3.43Å
317A97.4Very high92.1Very high0 Ų031.1 Ų31.10%016%0.161CC..  trans-56.6141.6172.300000109.4T319 Y321 L580 M589 C750A317-T319 HydrophobicContact CB-CG2 4.23Å; A317-T319 PolarHBondContact O-N 3.2Å; A317-T319 VanDerWaalsContact O-N 3.09Å; A317-Y321 PolarHBondContact N-OH 2.89Å; A317-Y321 PolarHBondContact O-OH 3.46Å; A317-L580 HydrophobicContact CB-CD1 3.84Å; A317-L580 HydrophobicContact CB-CD2 4.27Å; A317-L580 HydrophobicContact CB-CG 4.47Å; A317-M589 HydrophobicContact CB-CB 4.21Å; A317-M589 HydrophobicContact CB-SD 4.43Å; A317-C750 PolarHBondContact N-O 2.88Å
318F96.7Very high93.3Very high2 Ų222.4 Ų22.41%0.00912%0.124CC..SBendtrans-71.6107168.9-46-43.9000106.9C315 V536 Q539 A540 S543 L576 D592 L593C315-F318 WeakPolarHBondContact SG-CE1 3.46Å; F318-V536 VanDerWaalsContact C-CG1 3.48Å; F318-V536 HydrophobicContact CB-CG1 3.53Å; F318-V536 WeakPolarHBondContact O-CG1 3.37Å; F318-Q539 VanDerWaalsContact CA-OE1 3.22Å; F318-Q539 HydrophobicContact CB-CB 4.34Å; F318-Q539 HydrophobicContact CD1-CB 3.9Å; F318-Q539 HydrophobicContact CG-CB 4.44Å; F318-A540 HydrophobicContact CB-CB 4.43Å; F318-A540 HydrophobicContact CD2-CB 3.59Å; F318-A540 HydrophobicContact CE2-CB 3.91Å; F318-A540 HydrophobicContact CG-CB 3.94Å; F318-S543 VanDerWaalsContact CE1-OG 3.23Å; F318-S543 WeakPolarHBondContact CE1-OG 3.36Å; F318-L576 HydrophobicContact CD2-CD2 4.46Å; F318-L576 HydrophobicContact CE2-CD1 4.29Å; F318-L576 HydrophobicContact CE2-CD2 3.98Å; F318-D592 WeakPolarHBondContact O-CB 3.48Å; F318-L593 HydrophobicContact CB-CD2 3.8Å; F318-L593 HydrophobicContact CD2-CD2 3.53Å; F318-L593 HydrophobicContact CE2-CD2 4.35Å; F318-L593 HydrophobicContact CG-CD2 3.87Å
319T97Very high94.1Very high0 Ų020.2 Ų20.20%011%0.11CC..SBendtrans-162.7155.8-177.1-1800000110.6A317 Y321 Y325 R532 Q539 M589 D592A317-T319 HydrophobicContact CB-CG2 4.23Å; A317-T319 PolarHBondContact O-N 3.2Å; A317-T319 VanDerWaalsContact O-N 3.09Å; T319-Y321 HydrophobicContact CG2-CD1 4.01Å; T319-Y321 HydrophobicContact CG2-CD2 3.66Å; T319-Y321 HydrophobicContact CG2-CE1 3.67Å; T319-Y321 HydrophobicContact CG2-CE2 3.27Å; T319-Y321 HydrophobicContact CG2-CG 4Å; T319-Y321 WeakPolarHBondContact O-CD2 3.29Å; T319-Y321 PolarHBondContact O-N 3.4Å; T319-Y325 VanDerWaalsContact CG2-OH 3.29Å; T319-Y325 WeakPolarHBondContact CG2-OH 3.38Å; T319-Y325 VanDerWaalsContact OG1-CE1 3.24Å; T319-Y325 WeakPolarHBondContact OG1-CE1 3.39Å; T319-Y325 PolarHBondContact OG1-OH 3.32Å; T319-R532 PolarHBondContact OG1-NH2 2.82Å; T319-R532 VanDerWaalsContact OG1-NH2 3.16Å; T319-Q539 PolarHBondContact O-NE2 3.41Å; T319-Q539 PolarHBondContact O-OE1 3.37Å; T319-M589 HydrophobicContact CG2-CG 3.91Å; T319-M589 HydrophobicContact CG2-SD 4.3Å; T319-D592 WeakPolarHBondContact CA-OD2 3.27Å; T319-D592 WeakPolarHBondContact CB-OD2 3.27Å; T319-D592 PolarHBondContact OG1-OD2 3.5Å
320A94.4Very high94.5Very high0 Ų018.3 Ų18.30%010%0.102CC..  trans-91.575.8176.700000111.1S322 E323 R532 I535A320-S322 VanDerWaalsContact C-N 3.29Å; A320-S322 PolarHBondContact O-N 3.02Å; A320-E323 HydrophobicContact CB-CB 4.04Å; A320-E323 HydrophobicContact CB-CG 3.66Å; A320-E323 PolarHBondContact O-N 3.24Å; A320-R532 HydrophobicContact CB-CG 3.83Å; A320-I535 HydrophobicContact CB-CB 4.17Å; A320-I535 HydrophobicContact CB-CD1 3.96Å; A320-I535 HydrophobicContact CB-CG2 3.84Å
321Y94.2Very high94.6Very high11 Ų1122.6 Ų22.64%0.04312%0.117CC..G310 helixtrans-51.2-44.5-180-65.4-86000113.5K285 D286 A317 T319 E323 G324 M589 K751K285-Y321 HydrophobicContact CB-CD1 4.32Å; K285-Y321 HydrophobicContact CB-CD2 4.31Å; K285-Y321 HydrophobicContact CB-CG 4.21Å; K285-Y321 HydrophobicContact CD-CD1 3.95Å; K285-Y321 HydrophobicContact CD-CE1 3.99Å; K285-Y321 HydrophobicContact CG-CD1 4.01Å; K285-Y321 HydrophobicContact CG-CE1 4.41Å; K285-Y321 HydrophobicContact CG-CG 4.23Å; K285-Y321 VanDerWaalsContact O-CB 3.22Å; K285-Y321 WeakPolarHBondContact O-CB 3.27Å; D286-Y321 WeakPolarHBondContact OD1-CB 3.24Å; A317-Y321 PolarHBondContact N-OH 2.89Å; A317-Y321 PolarHBondContact O-OH 3.46Å; T319-Y321 HydrophobicContact CG2-CD1 4.01Å; T319-Y321 HydrophobicContact CG2-CD2 3.66Å; T319-Y321 HydrophobicContact CG2-CE1 3.67Å; T319-Y321 HydrophobicContact CG2-CE2 3.27Å; T319-Y321 HydrophobicContact CG2-CG 4Å; T319-Y321 WeakPolarHBondContact O-CD2 3.29Å; T319-Y321 PolarHBondContact O-N 3.4Å; Y321-E323 PolarHBondContact O-N 3.47Å; Y321-G324 PolarHBondContact O-N 2.94Å; Y321-M589 HydrophobicContact CE1-CE 4.5Å; Y321-M589 HydrophobicContact CE1-SD 4.46Å; Y321-K751 WeakPolarHBondContact CE1-O 3.43Å; Y321-K751 PolarHBondContact OH-O 3.31Å
322S91.5Very high94.4Very high33 Ų3322.7 Ų22.723%0.23112%0.123CC..G310 helixtrans-64.1-21.2180590000113.9A320A320-S322 VanDerWaalsContact C-N 3.29Å; A320-S322 PolarHBondContact O-N 3.02Å
323E91.8Very high94.4Very high49 Ų4923 Ų2323%0.22912%0.124CC..G310 helixtrans-90.3-6.7-178.1-53.8-49.8109.100113.1K263 A320 Y321 I535K263-E323 IonicContact NZ-OE1 3.53Å; K263-E323 PolarHBondContact NZ-OE1 2.87Å; K263-E323 IonicContact NZ-OE2 3.12Å; K263-E323 PolarHBondContact NZ-OE2 3.38Å; A320-E323 HydrophobicContact CB-CB 4.04Å; A320-E323 HydrophobicContact CB-CG 3.66Å; A320-E323 PolarHBondContact O-N 3.24Å; Y321-E323 PolarHBondContact O-N 3.47Å; E323-I535 HydrophobicContact CG-CD1 4.02Å
324G92.8Very high94.2Very high25 Ų2525.6 Ų25.626%0.25814%0.14SC..  trans65.2-164.5-174.300000112.9Y321 R532Y321-G324 PolarHBondContact O-N 2.94Å; G324-R532 PolarHBondContact O-NH1 2.84Å
325Y94.3Very high93.9Very high33 Ų3328.4 Ų28.413%0.12916%0.16CC..SBendtrans-141.818.6-172.6-53.1-89.2000113.8T319 Q327 G328 Y588 M589T319-Y325 VanDerWaalsContact CG2-OH 3.29Å; T319-Y325 WeakPolarHBondContact CG2-OH 3.38Å; T319-Y325 VanDerWaalsContact OG1-CE1 3.24Å; T319-Y325 WeakPolarHBondContact OG1-CE1 3.39Å; T319-Y325 PolarHBondContact OG1-OH 3.32Å; Y325-Q327 PolarHBondContact O-N 3.04Å; Y325-Q327 VanDerWaalsContact O-N 3.1Å; Y325-G328 PolarHBondContact O-N 2.9Å; Y325-Y588 VanDerWaalsContact CB-CD2 3.47Å; Y325-Y588 VanDerWaalsContact CD1-CB 3.48Å; Y325-Y588 HydrophobicContact CD1-CD2 4.33Å; Y325-Y588 HydrophobicContact CD1-CG 4.37Å; Y325-Y588 HydrophobicContact CG-CD2 4.15Å; Y325-M589 HydrophobicContact CE1-CE 4.4Å; Y325-M589 HydrophobicContact CE1-CG 3.7Å; Y325-M589 HydrophobicContact CE2-CE 3.99Å; Y325-M589 WeakPolarHBondContact OH-CE 3.38Å; Y325-M589 WeakPolarHBondContact OH-CG 3.36Å
326D89.6Confident93.6Very high148 Ų14832.2 Ų32.279%0.79117%0.174SC*.THydrogen-bonded Turntrans-61.8-22.7-177.3-55-26000112.8
327Q87.7Confident93.4Very high49 Ų4932.4 Ų32.423%0.22918%0.175CC..THydrogen-bonded Turntrans-101.67.8178.2-57.9-70.3-46.300112.8Y325 M333Y325-Q327 PolarHBondContact O-N 3.04Å; Y325-Q327 VanDerWaalsContact O-N 3.1Å; Q327-M333 HydrophobicContact CB-CE 4.48Å; Q327-M333 HydrophobicContact CB-CG 3.94Å; Q327-M333 HydrophobicContact CB-SD 4.43Å; Q327-M333 VanDerWaalsContact O-CG 3.27Å; Q327-M333 WeakPolarHBondContact O-CG 3.31Å
328G92.9Very high93Very high6 Ų635.8 Ų35.86%0.06220%0.199CC..  trans82.5-166.2-169.900000113.2Y325 Y588Y325-G328 PolarHBondContact O-N 2.9Å; G328-Y588 VanDerWaalsContact CA-CD1 3.46Å
329G96.1Very high92.6Very high0 Ų042.4 Ų42.40%023%0.23CC..SBendtrans-92.7-171.9169.300000111.1R331 G332 M333 Y588 E591 D592G329-R331 VanDerWaalsContact C-N 3.34Å; G329-R331 PolarHBondContact O-N 2.93Å; G329-G332 PolarHBondContact O-N 3.38Å; G329-M333 WeakPolarHBondContact O-CB 3.31Å; G329-M333 VanDerWaalsContact O-CG 3.27Å; G329-M333 WeakPolarHBondContact O-CG 3.45Å; G329-M333 PolarHBondContact O-N 3.48Å; G329-Y588 WeakPolarHBondContact CA-O 3.3Å; G329-E591 WeakPolarHBondContact CA-OE2 3.38Å; G329-E591 PolarHBondContact N-OE2 3.18Å; G329-D592 WeakPolarHBondContact CA-OD1 3.48Å
330L96.8Very high92.1Very high0 Ų045.3 Ų45.30%025%0.246CC..Hα-helixtrans-53-46.7-176.1-72.9175.5000112.8M333 V334 L529 R532 Y533 V536 D592 E595 M596L330-M333 PolarHBondContact O-N 3.1Å; L330-V334 VanDerWaalsContact O-CG2 3.27Å; L330-V334 WeakPolarHBondContact O-CG2 3.46Å; L330-V334 PolarHBondContact O-N 3.32Å; L330-L529 HydrophobicContact CD2-CD1 3.61Å; L330-R532 HydrophobicContact CD2-CB 3.95Å; L330-R532 HydrophobicContact CD2-CG 3.72Å; L330-R532 HydrophobicContact CG-CG 4.19Å; L330-Y533 HydrophobicContact CD1-CD1 4.17Å; L330-Y533 HydrophobicContact CD1-CE1 4.1Å; L330-Y533 HydrophobicContact CD1-CG 4.44Å; L330-Y533 HydrophobicContact CD2-CD1 4.48Å; L330-Y533 HydrophobicContact CD2-CD2 3.6Å; L330-Y533 HydrophobicContact CD2-CE2 3.76Å; L330-Y533 HydrophobicContact CD2-CG 3.99Å; L330-V536 HydrophobicContact CD1-CB 4.5Å; L330-V536 HydrophobicContact CD1-CG2 4.42Å; L330-D592 HydrophobicContact CD1-CB 4.45Å; L330-D592 WeakPolarHBondContact CG-OD1 2.92Å; L330-D592 PolarHBondContact N-OD1 3.42Å; L330-E595 HydrophobicContact CB-CB 4.04Å; L330-E595 HydrophobicContact CB-CG 3.8Å; L330-E595 HydrophobicContact CD1-CB 3.93Å; L330-M596 HydrophobicContact CD1-CE 3.36Å
331R93.1Very high91.9Very high96 Ų9646.8 Ų46.836%0.36226%0.255SS..Hα-helixtrans-62.7-46.5179.4-172.7178.4175.7173.40.9111.8G329 V334 S335 E591 E595 E682G329-R331 VanDerWaalsContact C-N 3.34Å; G329-R331 PolarHBondContact O-N 2.93Å; R331-V334 PolarHBondContact O-N 3.17Å; R331-S335 PolarHBondContact O-N 3.21Å; R331-S335 VanDerWaalsContact O-N 3.13Å; R331-E591 HydrophobicContact CB-CB 3.9Å; R331-E591 HydrophobicContact CB-CG 4.02Å; R331-E595 HydrophobicContact CB-CG 4.41Å; R331-E682 IonicContact CZ-OE1 3.76Å; R331-E682 IonicContact NH1-OE1 2.84Å; R331-E682 PolarHBondContact NH1-OE1 2.87Å; R331-E682 IonicContact NH1-OE2 3.89Å; R331-E682 IonicContact NH2-OE1 3.82Å; R331-E682 PolarHBondContact NH2-OE1 3.09Å; R331-E682 VanDerWaalsContact NH2-OE1 3.09Å; R331-E682 IonicContact NH2-OE2 2.85Å
332G92.1Very high91.4Very high23 Ų2350.9 Ų50.924%0.23728%0.277CS..Hα-helixtrans-64.8-40.5177.300000113.1G329 S335 R336 E591G329-G332 PolarHBondContact O-N 3.38Å; G332-S335 PolarHBondContact O-N 2.74Å; G332-R336 PolarHBondContact O-N 3.15Å; G332-E591 PolarHBondContact N-OE2 3.34Å; G332-E591 VanDerWaalsContact N-OE2 3.11Å
333M95.2Very high90.9Very high6 Ų654.9 Ų54.93%0.0330%0.301CS..Hα-helixtrans-64.3-40176.4-71.1179.873.600112.2Q327 G329 L330 R336 L337 K528 L529Q327-M333 HydrophobicContact CB-CE 4.48Å; Q327-M333 HydrophobicContact CB-CG 3.94Å; Q327-M333 HydrophobicContact CB-SD 4.43Å; Q327-M333 VanDerWaalsContact O-CG 3.27Å; Q327-M333 WeakPolarHBondContact O-CG 3.31Å; G329-M333 WeakPolarHBondContact O-CB 3.31Å; G329-M333 VanDerWaalsContact O-CG 3.27Å; G329-M333 WeakPolarHBondContact O-CG 3.45Å; G329-M333 PolarHBondContact O-N 3.48Å; L330-M333 PolarHBondContact O-N 3.1Å; M333-R336 PolarHBondContact O-N 3.49Å; M333-L337 VanDerWaalsContact O-CB 3.24Å; M333-L337 WeakPolarHBondContact O-CB 3.31Å; M333-L337 PolarHBondContact O-N 3.33Å; M333-K528 HydrophobicContact CE-CB 3.87Å; M333-L529 HydrophobicContact CB-CD1 3.7Å; M333-L529 HydrophobicContact CE-CB 4.01Å; M333-L529 HydrophobicContact CE-CD1 4.38Å; M333-L529 HydrophobicContact SD-CD1 4.34Å
334V94Very high90.4Very high56 Ų5653.7 Ų53.734%0.33930%0.298SS..Hα-helixtrans-63.2-43.9174.9169.30000111.1L330 R331 L337 S338 L529L330-V334 VanDerWaalsContact O-CG2 3.27Å; L330-V334 WeakPolarHBondContact O-CG2 3.46Å; L330-V334 PolarHBondContact O-N 3.32Å; R331-V334 PolarHBondContact O-N 3.17Å; V334-L337 PolarHBondContact O-N 3.42Å; V334-S338 PolarHBondContact O-N 3.08Å; V334-L529 HydrophobicContact CG2-CD1 4.05Å; V334-L529 HydrophobicContact CG2-CD2 3.82Å
335S91.2Very high89.7Confident59 Ų5954 Ų5441%0.41330%0.302SS..Hα-helixtrans-59.3-51176.5-165.60000111.4R331 G332 L337 S338 E339R331-S335 PolarHBondContact O-N 3.21Å; R331-S335 VanDerWaalsContact O-N 3.13Å; G332-S335 PolarHBondContact O-N 2.74Å; S335-L337 VanDerWaalsContact C-N 3.3Å; S335-L337 PolarHBondContact O-N 2.98Å; S335-S338 WeakPolarHBondContact O-CB 3.26Å; S335-S338 PolarHBondContact O-N 2.88Å; S335-S338 VanDerWaalsContact O-N 3.1Å; S335-S338 PolarHBondContact O-OG 2.97Å; S335-E339 PolarHBondContact O-N 2.85Å; S335-E339 VanDerWaalsContact O-N 3.1Å; S335-E339 PolarHBondContact OG-OE1 2.86Å
336R90.5Very high89.1Confident80 Ų8052.9 Ų52.930%0.30230%0.299SS..Hα-helixtrans-59.6-41178.8-174.7178.5-57.4-168.50.8112.6G332 M333 S338 E339 N340G332-R336 PolarHBondContact O-N 3.15Å; M333-R336 PolarHBondContact O-N 3.49Å; R336-S338 VanDerWaalsContact C-N 3.34Å; R336-E339 PolarHBondContact O-N 3.42Å; R336-N340 PolarHBondContact O-N 3.28Å
337L92.1Very high89.2Confident4 Ų446.2 Ų46.22%0.02126%0.263CS..Hα-helixtrans-63.2-42.8176.7-177.163.1000110.9M333 V334 S335 E339 N340 T341 C349 L517 T525 F526 L529M333-L337 VanDerWaalsContact O-CB 3.24Å; M333-L337 WeakPolarHBondContact O-CB 3.31Å; M333-L337 PolarHBondContact O-N 3.33Å; V334-L337 PolarHBondContact O-N 3.42Å; S335-L337 VanDerWaalsContact C-N 3.3Å; S335-L337 PolarHBondContact O-N 2.98Å; L337-E339 VanDerWaalsContact C-N 3.3Å; L337-E339 PolarHBondContact O-N 3.12Å; L337-N340 PolarHBondContact O-N 3.22Å; L337-N340 VanDerWaalsContact O-N 3.15Å; L337-T341 HydrophobicContact CD1-CG2 4.02Å; L337-T341 HydrophobicContact CG-CG2 4.18Å; L337-T341 WeakPolarHBondContact O-CG2 3.44Å; L337-T341 PolarHBondContact O-N 3.18Å; L337-T341 PolarHBondContact O-OG1 2.7Å; L337-C349 VanDerWaalsContact CD2-SG 3.51Å; L337-C349 VanDerWaalsContact CG-SG 3.54Å; L337-L517 HydrophobicContact CD1-CD2 3.87Å; L337-T525 HydrophobicContact CB-CG2 4.24Å; L337-T525 HydrophobicContact CD1-CG2 4.37Å; L337-F526 HydrophobicContact CD1-CB 4.2Å; L337-F526 HydrophobicContact CD2-CB 4.46Å; L337-F526 HydrophobicContact CD2-CD2 4.02Å; L337-L529 HydrophobicContact CD2-CD2 3.87Å
338S89.9Confident89.2Confident71 Ų7148.7 Ų48.750%0.49728%0.275SS..Hα-helixtrans-61.6-37.3177.575.30000112.8V334 S335 R336 N340 T341V334-S338 PolarHBondContact O-N 3.08Å; S335-S338 WeakPolarHBondContact O-CB 3.26Å; S335-S338 PolarHBondContact O-N 2.88Å; S335-S338 VanDerWaalsContact O-N 3.1Å; S335-S338 PolarHBondContact O-OG 2.97Å; R336-S338 VanDerWaalsContact C-N 3.34Å; S338-N340 VanDerWaalsContact C-N 3.31Å; S338-N340 PolarHBondContact O-N 3.23Å; S338-T341 PolarHBondContact O-OG1 3.46Å; S338-T341 VanDerWaalsContact O-OG1 3.07Å
339E87.7Confident89Confident142 Ų14250 Ų5066%0.66428%0.282SS*.Hα-helixtrans-67.9-30176.4-69.1163.8-154.900112.8S335 R336 L337S335-E339 PolarHBondContact O-N 2.85Å; S335-E339 VanDerWaalsContact O-N 3.1Å; S335-E339 PolarHBondContact OG-OE1 2.86Å; R336-E339 PolarHBondContact O-N 3.42Å; L337-E339 VanDerWaalsContact C-N 3.3Å; L337-E339 PolarHBondContact O-N 3.12Å
340N87.2Confident88.8Confident60 Ų6052.7 Ų52.732%0.32130%0.297SS..THydrogen-bonded Turntrans-99.29.1-175.6-73-23000114R336 L337 S338 A522R336-N340 PolarHBondContact O-N 3.28Å; L337-N340 PolarHBondContact O-N 3.22Å; L337-N340 VanDerWaalsContact O-N 3.15Å; S338-N340 VanDerWaalsContact C-N 3.31Å; S338-N340 PolarHBondContact O-N 3.23Å; N340-A522 HydrophobicContact CB-CB 4.47Å
341T88.5Confident88.6Confident31 Ų3153 Ų5319%0.1930%0.298CS..  trans-108.7148.1-177.155.60000113L337 S338 C349 L517L337-T341 HydrophobicContact CD1-CG2 4.02Å; L337-T341 HydrophobicContact CG-CG2 4.18Å; L337-T341 WeakPolarHBondContact O-CG2 3.44Å; L337-T341 PolarHBondContact O-N 3.18Å; L337-T341 PolarHBondContact O-OG1 2.7Å; S338-T341 PolarHBondContact O-OG1 3.46Å; S338-T341 VanDerWaalsContact O-OG1 3.07Å; T341-C349 HydrophobicContact CG2-CB 3.8Å; T341-C349 VanDerWaalsContact CG2-SG 3.51Å; T341-L517 HydrophobicContact CG2-CD2 3.83Å
342I83.9Confident88.5Confident98 Ų9849.8 Ų49.850%0.50329%0.287SS..  trans-102.6128.9177.3-55.9173.2000108.9S344 C516 A518I342-S344 PolarHBondContact O-N 2.84Å; I342-S344 VanDerWaalsContact O-N 3.1Å; I342-C516 PolarHBondContact N-O 3.46Å; I342-C516 VanDerWaalsContact O-CA 3.29Å; I342-C516 WeakPolarHBondContact O-CA 3.29Å; I342-C516 WeakPolarHBondContact O-CB 3.39Å; I342-C516 PolarHBondContact O-SG 2.73Å; I342-A518 HydrophobicContact CD1-CB 4.01Å
343P82.2Confident88.4Confident116 Ų11654.9 Ų54.975%0.75330%0.299SS*.  trans-61.9113.8175.8-23.133.3000111.8
344S80.3Confident88.2Confident24 Ų2454.6 Ų54.617%0.16830%0.298CS..  trans-101.2-8.9179.667.70000114.1I342 C346 F347 G512I342-S344 PolarHBondContact O-N 2.84Å; I342-S344 VanDerWaalsContact O-N 3.1Å; S344-C346 PolarHBondContact O-N 3.37Å; S344-F347 WeakPolarHBondContact OG-CB 3.37Å; S344-F347 PolarHBondContact OG-N 3.08Å; S344-F347 PolarHBondContact OG-O 3.27Å; S344-G512 WeakPolarHBondContact CB-O 3.32Å; S344-G512 PolarHBondContact OG-O 3.2Å
345G77.6Confident88.1Confident33 Ų3352 Ų5234%0.3428%0.282SS..SBendtrans75.6-36.8179.900000114.8
346C83.4Confident88.1Confident9 Ų952.3 Ų52.36%0.06128%0.284CS..SBendtrans-89.9-20.1176.7-660000113.7S344 L419 Y509S344-C346 PolarHBondContact O-N 3.37Å; C346-L419 HydrophobicContact CB-CD2 4.39Å; C346-Y509 VanDerWaalsContact O-CD2 3.26Å; C346-Y509 WeakPolarHBondContact O-CD2 3.37Å; C346-Y509 WeakPolarHBondContact O-CE2 3.22Å
347F90.8Very high88.1Confident7 Ų750.1 Ų50.13%0.03128%0.277CS..  trans-127.9137.5-179.2175.3-89.2000110.4S344 C349 V354 Y509 M513 C516 L517 F526S344-F347 WeakPolarHBondContact OG-CB 3.37Å; S344-F347 PolarHBondContact OG-N 3.08Å; S344-F347 PolarHBondContact OG-O 3.27Å; F347-C349 HydrophobicContact CE1-CB 4.01Å; F347-V354 HydrophobicContact CD2-CG2 4.42Å; F347-V354 HydrophobicContact CE2-CG1 4.41Å; F347-V354 HydrophobicContact CE2-CG2 3.53Å; F347-V354 HydrophobicContact CZ-CG2 3.8Å; F347-Y509 HydrophobicContact CB-CE2 4.31Å; F347-Y509 HydrophobicContact CD2-CE1 4.07Å; F347-Y509 AromaticContact CD2-CE2 3.78Å; F347-Y509 HydrophobicContact CD2-CE2 3.78Å; F347-Y509 AromaticContact CD2-CZ 3.51Å; F347-Y509 WeakPolarHBondContact CD2-OH 3.48Å; F347-Y509 HydrophobicContact CE2-CE1 4.43Å; F347-Y509 HydrophobicContact CG-CE2 4.49Å; F347-M513 HydrophobicContact CB-CB 4.49Å; F347-M513 HydrophobicContact CD1-CB 4.39Å; F347-M513 HydrophobicContact CD2-CB 3.58Å; F347-M513 HydrophobicContact CD2-CG 3.93Å; F347-M513 HydrophobicContact CE1-CG 4.22Å; F347-M513 HydrophobicContact CE2-CB 3.78Å; F347-M513 HydrophobicContact CE2-CG 3.57Å; F347-M513 HydrophobicContact CE2-SD 3.95Å; F347-M513 HydrophobicContact CG-CB 3.91Å; F347-M513 HydrophobicContact CG-CG 4.41Å; F347-M513 HydrophobicContact CZ-CB 4.28Å; F347-M513 HydrophobicContact CZ-CG 3.73Å; F347-M513 HydrophobicContact CZ-SD 4.37Å; F347-C516 HydrophobicContact CD1-CB 3.57Å; F347-C516 HydrophobicContact CE1-CB 4.11Å; F347-C516 HydrophobicContact CG-CB 4.49Å; F347-L517 HydrophobicContact CE1-CD1 4.48Å; F347-L517 HydrophobicContact CZ-CD1 4.43Å; F347-F526 AromaticContact CZ-CE2 3.96Å; F347-F526 HydrophobicContact CZ-CE2 3.96Å; F347-F526 HydrophobicContact CZ-CZ 4.21Å
348E87.8Confident88.1Confident102 Ų10250 Ų5048%0.47728%0.276SS..  trans-115.7130.2173.7-64.6-179.8150.700108.8D350 R353 V354E348-D350 PolarHBondContact O-N 3.2Å; E348-R353 IonicContact OE1-NH1 3.66Å; E348-R353 PolarHBondContact OE1-NH1 2.84Å; E348-R353 WeakPolarHBondContact OE2-CD 3.49Å; E348-R353 IonicContact OE2-CZ 3.47Å; E348-R353 IonicContact OE2-NE 3.61Å; E348-R353 IonicContact OE2-NH1 2.85Å; E348-R353 PolarHBondContact OE2-NH1 2.97Å; E348-V354 WeakPolarHBondContact O-CG2 3.31Å
349C89.7Confident88.1Confident33 Ų3349.5 Ų49.522%0.22326%0.263CS..SBendtrans-79.454.9-176.6-150.90000112.7L337 T341 F347L337-C349 VanDerWaalsContact CD2-SG 3.51Å; L337-C349 VanDerWaalsContact CG-SG 3.54Å; T341-C349 HydrophobicContact CG2-CB 3.8Å; T341-C349 VanDerWaalsContact CG2-SG 3.51Å; F347-C349 HydrophobicContact CE1-CB 4.01Å
350D91.2Very high88.3Confident57 Ų5743.9 Ų43.931%0.30524%0.244SC..  trans-128.2109.4174.9177-15.9000108.7E348 K352 R353 V354E348-D350 PolarHBondContact O-N 3.2Å; D350-K352 PolarHBondContact O-N 3.25Å; D350-K352 VanDerWaalsContact OD1-CB 3.31Å; D350-K352 WeakPolarHBondContact OD1-CB 3.47Å; D350-K352 PolarHBondContact OD1-N 2.96Å; D350-R353 HydrophobicContact CB-CB 4.17Å; D350-R353 HydrophobicContact CB-CG 4.03Å; D350-R353 WeakPolarHBondContact O-CA 3.09Å; D350-R353 PolarHBondContact O-N 3.31Å; D350-R353 IonicContact OD2-NE 2.64Å; D350-V354 WeakPolarHBondContact O-CG2 3.42Å; D350-V354 PolarHBondContact O-N 3.07Å
351L91.6Very high88.6Confident5 Ų541 Ų413%0.02623%0.228CC..Hα-helixtrans-53-32.1-177.7-74.2172.1000113.8W229 A355 F526 L529 L530 Y533 L626W229-L351 HydrophobicContact CH2-CD2 3.73Å; W229-L351 HydrophobicContact CZ2-CD2 4.07Å; L351-A355 VanDerWaalsContact O-CB 3.27Å; L351-A355 WeakPolarHBondContact O-CB 3.36Å; L351-A355 PolarHBondContact O-N 2.64Å; L351-F526 HydrophobicContact CD2-CD2 4.32Å; L351-F526 HydrophobicContact CD2-CE1 3.87Å; L351-F526 HydrophobicContact CD2-CE2 3.62Å; L351-F526 HydrophobicContact CD2-CZ 3.37Å; L351-F526 HydrophobicContact CG-CE2 4.24Å; L351-F526 HydrophobicContact CG-CZ 4.43Å; L351-L529 HydrophobicContact CD1-CB 4.08Å; L351-L529 HydrophobicContact CD1-CD2 3.59Å; L351-L529 HydrophobicContact CD1-CG 3.55Å; L351-L529 HydrophobicContact CG-CD2 4.22Å; L351-L530 HydrophobicContact CD1-CB 4.27Å; L351-L530 HydrophobicContact CD2-CB 4.19Å; L351-Y533 HydrophobicContact CD1-CD2 3.56Å; L351-Y533 HydrophobicContact CD1-CE2 3.96Å; L351-Y533 HydrophobicContact CD1-CG 4.5Å; L351-L626 HydrophobicContact CB-CD1 4.14Å
352K90.7Very high88.8Confident30 Ų3041.9 Ų41.913%0.1324%0.235CC..Hα-helixtrans-69.5-40.5179.4-58.8161.2-172.9165.80109.9D350 S356 Y533 E595 G627D350-K352 PolarHBondContact O-N 3.25Å; D350-K352 VanDerWaalsContact OD1-CB 3.31Å; D350-K352 WeakPolarHBondContact OD1-CB 3.47Å; D350-K352 PolarHBondContact OD1-N 2.96Å; K352-S356 PolarHBondContact O-N 2.87Å; K352-S356 VanDerWaalsContact O-N 3.1Å; K352-Y533 WeakPolarHBondContact CE-OH 3.41Å; K352-Y533 PolarHBondContact NZ-OH 3.39Å; K352-E595 IonicContact NZ-OE2 3.13Å; K352-E595 PolarHBondContact NZ-OE2 2.74Å; K352-G627 WeakPolarHBondContact O-CA 3.43Å
353R90.3Very high89.2Confident130 Ų13041 Ų4149%0.49124%0.235SC..Hα-helixtrans-73.9-40.3176.4-61.5-171.8-172-163.3-1.3112E348 D350 A355 S356 K357E348-R353 IonicContact OE1-NH1 3.66Å; E348-R353 PolarHBondContact OE1-NH1 2.84Å; E348-R353 WeakPolarHBondContact OE2-CD 3.49Å; E348-R353 IonicContact OE2-CZ 3.47Å; E348-R353 IonicContact OE2-NE 3.61Å; E348-R353 IonicContact OE2-NH1 2.85Å; E348-R353 PolarHBondContact OE2-NH1 2.97Å; D350-R353 HydrophobicContact CB-CB 4.17Å; D350-R353 HydrophobicContact CB-CG 4.03Å; D350-R353 WeakPolarHBondContact O-CA 3.09Å; D350-R353 PolarHBondContact O-N 3.31Å; D350-R353 IonicContact OD2-NE 2.64Å; R353-A355 VanDerWaalsContact C-N 3.28Å; R353-A355 PolarHBondContact O-N 2.97Å; R353-S356 WeakPolarHBondContact O-CB 3.28Å; R353-S356 PolarHBondContact O-N 3.3Å; R353-K357 WeakPolarHBondContact O-CB 3.36Å; R353-K357 PolarHBondContact O-N 2.82Å
354V92.5Very high89.7Confident0 Ų035.7 Ų35.70%020%0.2CC..Hα-helixtrans-56-47.5172.1177.30000109.8W229 F347 E348 D350 S356 K357 L358 Y509 F526W229-V354 HydrophobicContact CH2-CB 4.03Å; W229-V354 HydrophobicContact CH2-CG1 3.46Å; W229-V354 VanDerWaalsContact CH2-CG1 3.46Å; W229-V354 HydrophobicContact CZ3-CG1 3.48Å; W229-V354 VanDerWaalsContact CZ3-CG1 3.48Å; F347-V354 HydrophobicContact CD2-CG2 4.42Å; F347-V354 HydrophobicContact CE2-CG1 4.41Å; F347-V354 HydrophobicContact CE2-CG2 3.53Å; F347-V354 HydrophobicContact CZ-CG2 3.8Å; E348-V354 WeakPolarHBondContact O-CG2 3.31Å; D350-V354 WeakPolarHBondContact O-CG2 3.42Å; D350-V354 PolarHBondContact O-N 3.07Å; V354-S356 PolarHBondContact O-N 3.43Å; V354-K357 PolarHBondContact O-N 3.42Å; V354-K357 VanDerWaalsContact O-N 3.17Å; V354-L358 HydrophobicContact CG1-CD1 3.9Å; V354-L358 HydrophobicContact CG1-CG 4.21Å; V354-L358 WeakPolarHBondContact O-CB 3.49Å; V354-L358 VanDerWaalsContact O-CG 3.31Å; V354-L358 WeakPolarHBondContact O-CG 3.48Å; V354-L358 PolarHBondContact O-N 3.11Å; V354-Y509 WeakPolarHBondContact CA-OH 3.31Å; V354-Y509 WeakPolarHBondContact CG1-OH 3.5Å; V354-Y509 WeakPolarHBondContact CG2-OH 3.39Å; V354-F526 HydrophobicContact CG2-CZ 4.38Å
355A91.5Very high90.3Very high0 Ų036.9 Ų36.90%020%0.203CC..Hα-helixtrans-61.3-45.1177.600000112.4F228 W229 L351 R353 K357 R359 D625 L626F228-A355 HydrophobicContact CE1-CB 4.17Å; F228-A355 WeakPolarHBondContact CE1-O 3.26Å; F228-A355 WeakPolarHBondContact CZ-O 3.4Å; W229-A355 HydrophobicContact CZ2-CB 4.47Å; L351-A355 VanDerWaalsContact O-CB 3.27Å; L351-A355 WeakPolarHBondContact O-CB 3.36Å; L351-A355 PolarHBondContact O-N 2.64Å; R353-A355 VanDerWaalsContact C-N 3.28Å; R353-A355 PolarHBondContact O-N 2.97Å; A355-K357 VanDerWaalsContact C-N 3.3Å; A355-K357 PolarHBondContact O-N 3.12Å; A355-R359 WeakPolarHBondContact O-CB 3.43Å; A355-R359 PolarHBondContact O-N 3.41Å; A355-R359 VanDerWaalsContact O-N 3.1Å; A355-D625 HydrophobicContact CB-CB 4.24Å; A355-D625 VanDerWaalsContact CB-OD1 3.26Å; A355-D625 WeakPolarHBondContact CB-OD1 3.36Å; A355-L626 HydrophobicContact CB-CB 4.1Å
356S90.2Very high91Very high67 Ų6737.9 Ų37.947%0.46921%0.208SC..Hα-helixtrans-58.8-40.2174-1700000113.1K352 R353 V354 R359 G360K352-S356 PolarHBondContact O-N 2.87Å; K352-S356 VanDerWaalsContact O-N 3.1Å; R353-S356 WeakPolarHBondContact O-CB 3.28Å; R353-S356 PolarHBondContact O-N 3.3Å; V354-S356 PolarHBondContact O-N 3.43Å; S356-R359 PolarHBondContact O-N 3.4Å; S356-G360 PolarHBondContact O-N 3.22Å
357K91.1Very high91.5Very high34 Ų3439.8 Ų39.815%0.14822%0.222CC..Hα-helixtrans-69.5-48.4-177.7-176.358.8160.8168.40111.8R353 V354 A355 R359 G360 M361 Q408 F409 Y509R353-K357 WeakPolarHBondContact O-CB 3.36Å; R353-K357 PolarHBondContact O-N 2.82Å; V354-K357 PolarHBondContact O-N 3.42Å; V354-K357 VanDerWaalsContact O-N 3.17Å; A355-K357 VanDerWaalsContact C-N 3.3Å; A355-K357 PolarHBondContact O-N 3.12Å; K357-R359 PolarHBondContact O-N 2.84Å; K357-G360 PolarHBondContact O-N 3.39Å; K357-M361 HydrophobicContact CD-CE 4Å; K357-M361 HydrophobicContact CG-CE 3.9Å; K357-M361 HydrophobicContact CG-SD 4.46Å; K357-M361 WeakPolarHBondContact O-CG 3.37Å; K357-M361 PolarHBondContact O-N 2.74Å; K357-M361 VanDerWaalsContact O-N 3.08Å; K357-Q408 PolarHBondContact NZ-O 2.89Å; K357-F409 VanDerWaalsContact NZ-CD1 3.29Å; K357-F409 VanDerWaalsContact NZ-CE1 3.28Å; K357-Y509 HydrophobicContact CB-CE2 4.4Å; K357-Y509 HydrophobicContact CG-CD2 4.01Å; K357-Y509 HydrophobicContact CG-CE1 4.32Å; K357-Y509 HydrophobicContact CG-CE2 3.59Å
358L92.3Very high91.7Very high1 Ų139.8 Ų39.81%0.00522%0.222CC..Hα-helixtrans-60.5-29.6175.7-67.5179.5000111.7F228 W229 F231 L232 V354 M361 S362 Y509F228-L358 HydrophobicContact CE1-CB 3.44Å; F228-L358 VanDerWaalsContact CE1-CB 3.44Å; F228-L358 HydrophobicContact CE1-CD1 3.87Å; F228-L358 HydrophobicContact CE1-CG 4.29Å; F228-L358 HydrophobicContact CE2-CB 4.45Å; F228-L358 HydrophobicContact CZ-CB 3.32Å; W229-L358 HydrophobicContact CE3-CD1 3.72Å; W229-L358 HydrophobicContact CH2-CD1 4.4Å; W229-L358 HydrophobicContact CZ3-CD1 3.67Å; F231-L358 HydrophobicContact CD1-CD2 3.93Å; F231-L358 HydrophobicContact CE1-CD2 4.01Å; L232-L358 HydrophobicContact CB-CD1 4.01Å; L232-L358 HydrophobicContact CB-CD2 4.22Å; L232-L358 HydrophobicContact CD1-CD2 4.2Å; L232-L358 HydrophobicContact CD2-CD1 4.24Å; V354-L358 HydrophobicContact CG1-CD1 3.9Å; V354-L358 HydrophobicContact CG1-CG 4.21Å; V354-L358 WeakPolarHBondContact O-CB 3.49Å; V354-L358 VanDerWaalsContact O-CG 3.31Å; V354-L358 WeakPolarHBondContact O-CG 3.48Å; V354-L358 PolarHBondContact O-N 3.11Å; L358-M361 HydrophobicContact CD2-SD 4.19Å; L358-M361 PolarHBondContact O-N 2.96Å; L358-S362 WeakPolarHBondContact O-CB 3.17Å; L358-S362 PolarHBondContact O-N 2.72Å; L358-Y509 HydrophobicContact CD2-CD1 4.31Å; L358-Y509 HydrophobicContact CD2-CE1 3.96Å
359R90.1Very high91.9Very high61 Ų6141.5 Ų41.523%0.2322%0.224CC..Hα-helixtrans-74.7-42.3-178.3-174.4-162.6-57.3-115.316.9110F228 A355 S356 K357 M361 S362 T363 D625 A628F228-R359 HydrophobicContact CE2-CB 3.68Å; F228-R359 HydrophobicContact CE2-CG 4.21Å; F228-R359 HydrophobicContact CZ-CB 3.78Å; F228-R359 VanDerWaalsContact CZ-N 3.25Å; A355-R359 WeakPolarHBondContact O-CB 3.43Å; A355-R359 PolarHBondContact O-N 3.41Å; A355-R359 VanDerWaalsContact O-N 3.1Å; S356-R359 PolarHBondContact O-N 3.4Å; K357-R359 PolarHBondContact O-N 2.84Å; R359-M361 VanDerWaalsContact C-N 3.27Å; R359-M361 PolarHBondContact O-N 3.03Å; R359-S362 PolarHBondContact O-N 3.26Å; R359-T363 VanDerWaalsContact O-CB 3.29Å; R359-T363 WeakPolarHBondContact O-CB 3.21Å; R359-T363 PolarHBondContact O-N 2.9Å; R359-T363 PolarHBondContact O-OG1 2.77Å; R359-D625 IonicContact CZ-OD1 3.43Å; R359-D625 IonicContact CZ-OD2 2.8Å; R359-D625 IonicContact NE-OD1 3.74Å; R359-D625 IonicContact NE-OD2 3.59Å; R359-D625 PolarHBondContact NE-OD2 3.13Å; R359-D625 IonicContact NH1-OD2 3.9Å; R359-D625 IonicContact NH2-OD1 3.08Å; R359-D625 PolarHBondContact NH2-OD1 3.47Å; R359-D625 IonicContact NH2-OD2 3.91Å; R359-D625 PolarHBondContact NH2-OD2 3.27Å; R359-A628 VanDerWaalsContact NH2-N 3.16Å; R359-A628 PolarHBondContact NH2-O 2.99Å
360G91.4Very high92Very high24 Ų2442.6 Ų42.625%0.24724%0.236CC..Hα-helixtrans-56.3-45.317100000111.1S356 K357 T364S356-G360 PolarHBondContact O-N 3.22Å; K357-G360 PolarHBondContact O-N 3.39Å; G360-T364 WeakPolarHBondContact O-CB 3.44Å; G360-T364 PolarHBondContact O-N 2.94Å; G360-T364 PolarHBondContact O-OG1 3.46Å
361M93.7Very high91.9Very high0 Ų040.5 Ų40.50%022%0.224CC..Hα-helixtrans-63.7-51.5177.7-66.9166.6172.100112.6F231 K357 L358 R359 T363 T364 E365 F409 H502 V506 Y509F231-M361 HydrophobicContact CE1-CB 3.89Å; F231-M361 HydrophobicContact CE1-SD 4.19Å; F231-M361 HydrophobicContact CE2-CB 4.45Å; F231-M361 HydrophobicContact CZ-CB 3.61Å; K357-M361 HydrophobicContact CD-CE 4Å; K357-M361 HydrophobicContact CG-CE 3.9Å; K357-M361 HydrophobicContact CG-SD 4.46Å; K357-M361 WeakPolarHBondContact O-CG 3.37Å; K357-M361 PolarHBondContact O-N 2.74Å; K357-M361 VanDerWaalsContact O-N 3.08Å; L358-M361 HydrophobicContact CD2-SD 4.19Å; L358-M361 PolarHBondContact O-N 2.96Å; R359-M361 VanDerWaalsContact C-N 3.27Å; R359-M361 PolarHBondContact O-N 3.03Å; M361-T363 VanDerWaalsContact C-N 3.32Å; M361-T363 PolarHBondContact O-N 3.49Å; M361-T364 WeakPolarHBondContact O-CA 3.39Å; M361-T364 VanDerWaalsContact O-CB 3.28Å; M361-T364 WeakPolarHBondContact O-CB 3.25Å; M361-T364 PolarHBondContact O-N 3.1Å; M361-E365 PolarHBondContact O-N 2.9Å; M361-F409 HydrophobicContact CE-CE1 4.2Å; M361-F409 HydrophobicContact CE-CE2 3.81Å; M361-F409 HydrophobicContact CE-CZ 3.25Å; M361-H502 PolarHBondContact O-CE1 2.69Å; M361-H502 VanDerWaalsContact O-CE1 3.25Å; M361-V506 HydrophobicContact CB-CG2 4.32Å; M361-V506 HydrophobicContact CG-CG2 4.15Å; M361-V506 HydrophobicContact SD-CG2 4.03Å; M361-Y509 HydrophobicContact CE-CD1 4.1Å; M361-Y509 HydrophobicContact CE-CD2 4.27Å; M361-Y509 HydrophobicContact CE-CG 3.76Å; M361-Y509 HydrophobicContact SD-CD1 4.37Å
362S92.2Very high91.9Very high48 Ų4843.8 Ų43.834%0.33624%0.236SC..Hα-helixtrans-61.4-38.6179176.10000112.5L358 R359 T364 E365 A366L358-S362 WeakPolarHBondContact O-CB 3.17Å; L358-S362 PolarHBondContact O-N 2.72Å; R359-S362 PolarHBondContact O-N 3.26Å; S362-T364 VanDerWaalsContact C-N 3.3Å; S362-T364 PolarHBondContact O-N 3.3Å; S362-E365 PolarHBondContact O-N 3.31Å; S362-A366 WeakPolarHBondContact O-CB 3.42Å; S362-A366 PolarHBondContact O-N 3.47Å
363T91.9Very high91.8Very high80 Ų8047 Ų4749%0.49125%0.254SS..Hα-helixtrans-65.2-36.9174.5-54.50000111.4R359 M361 A366 S367R359-T363 VanDerWaalsContact O-CB 3.29Å; R359-T363 WeakPolarHBondContact O-CB 3.21Å; R359-T363 PolarHBondContact O-N 2.9Å; R359-T363 PolarHBondContact O-OG1 2.77Å; M361-T363 VanDerWaalsContact C-N 3.32Å; M361-T363 PolarHBondContact O-N 3.49Å; T363-A366 PolarHBondContact O-N 3.32Å; T363-S367 WeakPolarHBondContact O-CB 3.37Å; T363-S367 PolarHBondContact O-N 3.25Å; T363-S367 PolarHBondContact O-OG 2.89Å
364T94.6Very high91.6Very high5 Ų544.5 Ų44.53%0.03125%0.248CC..Hα-helixtrans-65-46.2175.6-56.30000110.9G360 M361 S362 A366 S367 L368 L401 I405 Q408G360-T364 WeakPolarHBondContact O-CB 3.44Å; G360-T364 PolarHBondContact O-N 2.94Å; G360-T364 PolarHBondContact O-OG1 3.46Å; M361-T364 WeakPolarHBondContact O-CA 3.39Å; M361-T364 VanDerWaalsContact O-CB 3.28Å; M361-T364 WeakPolarHBondContact O-CB 3.25Å; M361-T364 PolarHBondContact O-N 3.1Å; S362-T364 VanDerWaalsContact C-N 3.3Å; S362-T364 PolarHBondContact O-N 3.3Å; T364-A366 VanDerWaalsContact C-N 3.34Å; T364-A366 PolarHBondContact O-N 3.34Å; T364-S367 WeakPolarHBondContact O-CB 3.4Å; T364-S367 PolarHBondContact O-N 3.25Å; T364-S367 VanDerWaalsContact O-N 3.13Å; T364-L368 HydrophobicContact CG2-CD1 4.31Å; T364-L368 WeakPolarHBondContact O-CG 3.42Å; T364-L368 PolarHBondContact O-N 3.21Å; T364-L401 HydrophobicContact CG2-CD1 3.99Å; T364-I405 HydrophobicContact CG2-CD1 3.9Å; T364-I405 HydrophobicContact CG2-CG1 3.53Å; T364-Q408 PolarHBondContact OG1-NE2 3.46Å
365E93Very high91.3Very high49 Ų4944.7 Ų44.723%0.22925%0.249CC..Hα-helixtrans-62.1-41.2176.8-159.4-163.512200112F231 H235 M361 S362 S367 L368 R369F231-E365 VanDerWaalsContact CE2-OE2 3.29Å; F231-E365 WeakPolarHBondContact CE2-OE2 3.27Å; H235-E365 IonicContact CE1-OE2 3.96Å; H235-E365 IonicContact NE2-OE2 3.76Å; H235-E365 PolarHBondContact NE2-OE2 3.49Å; M361-E365 PolarHBondContact O-N 2.9Å; S362-E365 PolarHBondContact O-N 3.31Å; E365-S367 VanDerWaalsContact C-N 3.31Å; E365-S367 PolarHBondContact O-N 3.39Å; E365-L368 PolarHBondContact O-N 3.18Å; E365-R369 WeakPolarHBondContact O-CB 3.41Å; E365-R369 PolarHBondContact O-N 3.28Å; E365-R369 IonicContact OE1-CZ 2.77Å; E365-R369 IonicContact OE1-NH1 3.97Å; E365-R369 PolarHBondContact OE1-NH1 2.98Å; E365-R369 VanDerWaalsContact OE1-NH1 3.08Å; E365-R369 IonicContact OE1-NH2 3.98Å; E365-R369 PolarHBondContact OE1-NH2 3.02Å
366A92Very high91.1Very high53 Ų5348.3 Ų48.344%0.43827%0.268SS..Hα-helixtrans-62.6-38.8173.800000112.2S362 T363 T364 R369 A370S362-A366 WeakPolarHBondContact O-CB 3.42Å; S362-A366 PolarHBondContact O-N 3.47Å; T363-A366 PolarHBondContact O-N 3.32Å; T364-A366 VanDerWaalsContact C-N 3.34Å; T364-A366 PolarHBondContact O-N 3.34Å; A366-R369 PolarHBondContact O-N 3.16Å; A366-A370 WeakPolarHBondContact O-CB 2.96Å; A366-A370 PolarHBondContact O-N 3.01Å
367S93.3Very high90.9Very high50 Ų5049.8 Ų49.835%0.3527%0.271SS..Hα-helixtrans-67.6-41.9177.3-56.60000111.9T363 T364 E365 A370 L371T363-S367 WeakPolarHBondContact O-CB 3.37Å; T363-S367 PolarHBondContact O-N 3.25Å; T363-S367 PolarHBondContact O-OG 2.89Å; T364-S367 WeakPolarHBondContact O-CB 3.4Å; T364-S367 PolarHBondContact O-N 3.25Å; T364-S367 VanDerWaalsContact O-N 3.13Å; E365-S367 VanDerWaalsContact C-N 3.31Å; E365-S367 PolarHBondContact O-N 3.39Å; S367-A370 PolarHBondContact O-N 3.45Å; S367-L371 VanDerWaalsContact O-CB 3.29Å; S367-L371 WeakPolarHBondContact O-CB 3.41Å; S367-L371 PolarHBondContact O-N 3.12Å
368L93.9Very high90.6Very high6 Ų649 Ų493%0.03127%0.27CS..Hα-helixtrans-60.6-45.2173.8-72.4168.7000111.2T364 E365 L371 R372 L401 L498 E499 H502T364-L368 HydrophobicContact CG2-CD1 4.31Å; T364-L368 WeakPolarHBondContact O-CG 3.42Å; T364-L368 PolarHBondContact O-N 3.21Å; E365-L368 PolarHBondContact O-N 3.18Å; L368-L371 PolarHBondContact O-N 3.38Å; L368-R372 PolarHBondContact O-N 3.43Å; L368-L401 HydrophobicContact CD2-CD2 3.41Å; L368-L401 VanDerWaalsContact CD2-CD2 3.41Å; L368-L401 HydrophobicContact CD2-CG 4.5Å; L368-L401 HydrophobicContact CG-CD2 3.87Å; L368-L498 HydrophobicContact CD2-CB 3.68Å; L368-L498 HydrophobicContact CD2-CD1 4.24Å; L368-E499 HydrophobicContact CD1-CG 4.2Å; L368-H502 HydrophobicContact CD1-CB 4.02Å
369R93.1Very high90.3Very high138 Ų13850.5 Ų50.552%0.52128%0.277SS..Hα-helixtrans-63-44.3177.3-175.4176.1-72.9100.5-5.1112.3E365 A366 R372 L373E365-R369 WeakPolarHBondContact O-CB 3.41Å; E365-R369 PolarHBondContact O-N 3.28Å; E365-R369 IonicContact OE1-CZ 2.77Å; E365-R369 IonicContact OE1-NH1 3.97Å; E365-R369 PolarHBondContact OE1-NH1 2.98Å; E365-R369 VanDerWaalsContact OE1-NH1 3.08Å; E365-R369 IonicContact OE1-NH2 3.98Å; E365-R369 PolarHBondContact OE1-NH2 3.02Å; A366-R369 PolarHBondContact O-N 3.16Å; R369-R372 PolarHBondContact O-N 3.34Å; R369-L373 WeakPolarHBondContact O-CG 3.37Å; R369-L373 PolarHBondContact O-N 3.45Å
370A91.1Very high89.9Confident57 Ų5754.9 Ų54.947%0.47130%0.3SS..Hα-helixtrans-62.8-42.5176.400000111.8A366 S367 R372 L373 Q374A366-A370 WeakPolarHBondContact O-CB 2.96Å; A366-A370 PolarHBondContact O-N 3.01Å; S367-A370 PolarHBondContact O-N 3.45Å; A370-R372 VanDerWaalsContact C-N 3.32Å; A370-R372 PolarHBondContact O-N 2.89Å; A370-L373 PolarHBondContact O-N 2.77Å; A370-Q374 WeakPolarHBondContact O-CB 3.08Å; A370-Q374 PolarHBondContact O-N 3.18Å
371L90.2Very high89.3Confident13 Ų1359.4 Ų59.47%0.06832%0.315CS..Hα-helixtrans-62-39.7176.9-174.461.9000111.8S367 L368 F375 L394 T397 L495S367-L371 VanDerWaalsContact O-CB 3.29Å; S367-L371 WeakPolarHBondContact O-CB 3.41Å; S367-L371 PolarHBondContact O-N 3.12Å; L368-L371 PolarHBondContact O-N 3.38Å; L371-F375 WeakPolarHBondContact O-CB 3.32Å; L371-F375 PolarHBondContact O-N 3.24Å; L371-L394 HydrophobicContact CD1-CD1 4.01Å; L371-L394 HydrophobicContact CD2-CD1 3.63Å; L371-L394 HydrophobicContact CG-CD1 3.93Å; L371-T397 HydrophobicContact CD1-CG2 4.15Å; L371-T397 HydrophobicContact CD2-CG2 4.33Å; L371-L495 HydrophobicContact CD2-CD2 3.55Å; L371-L495 HydrophobicContact CG-CD2 3.82Å
372R90.7Very high88.5Confident74 Ų7465.6 Ų65.628%0.27936%0.355SS..Hα-helixtrans-67.7-39.9176.4-164.6165-167163.1-3.4113L368 R369 A370 F375 L376 E492 L495 E499L368-R372 PolarHBondContact O-N 3.43Å; R369-R372 PolarHBondContact O-N 3.34Å; A370-R372 VanDerWaalsContact C-N 3.32Å; A370-R372 PolarHBondContact O-N 2.89Å; R372-F375 WeakPolarHBondContact O-CB 3.3Å; R372-F375 PolarHBondContact O-N 3.46Å; R372-L376 WeakPolarHBondContact O-CG 3.39Å; R372-L376 PolarHBondContact O-N 3.1Å; R372-E492 IonicContact CZ-OE1 3.57Å; R372-E492 IonicContact NE-OE1 3.75Å; R372-E492 IonicContact NE-OE2 2.9Å; R372-E492 IonicContact NH2-OE1 2.68Å; R372-E492 PolarHBondContact NH2-OE1 3.32Å; R372-E492 IonicContact NH2-OE2 2.8Å; R372-L495 HydrophobicContact CB-CD1 4.46Å; R372-L495 HydrophobicContact CG-CD1 4.32Å; R372-E499 IonicContact CZ-OE1 2.84Å; R372-E499 IonicContact NH1-OE1 3.79Å; R372-E499 PolarHBondContact NH1-OE1 2.87Å; R372-E499 IonicContact NH1-OE2 2.81Å; R372-E499 PolarHBondContact NH1-OE2 3.13Å
373L88.9Confident87.9Confident97 Ų9764.7 Ų64.751%0.50835%0.353SS..Hα-helixtrans-64.1-46.4174.4-70.9173.3000111.3R369 A370 F375 L376 D377R369-L373 WeakPolarHBondContact O-CG 3.37Å; R369-L373 PolarHBondContact O-N 3.45Å; A370-L373 PolarHBondContact O-N 2.77Å; L373-F375 PolarHBondContact O-N 3.17Å; L373-L376 PolarHBondContact O-N 3.14Å; L373-L376 VanDerWaalsContact O-N 3.14Å; L373-D377 PolarHBondContact O-N 2.66Å
374Q85.7Confident87.7Confident78 Ų7861.7 Ų61.736%0.36433%0.334SS..Hα-helixtrans-57.8-39175.8-170.1-170.8-4.600111.8A370 A378A370-Q374 WeakPolarHBondContact O-CB 3.08Å; A370-Q374 PolarHBondContact O-N 3.18Å; Q374-A378 WeakPolarHBondContact O-CB 2.82Å; Q374-A378 PolarHBondContact O-N 3.1Å; Q374-A378 VanDerWaalsContact O-N 3.12Å
375F87.3Confident87.3Confident3 Ų364 Ų641%0.01336%0.358CS..Hα-helixtrans-66.7-45.7175.5171.1-99.7000112.2L371 R372 L373 D377 A378 F379 H488 A491 L495L371-F375 WeakPolarHBondContact O-CB 3.32Å; L371-F375 PolarHBondContact O-N 3.24Å; R372-F375 WeakPolarHBondContact O-CB 3.3Å; R372-F375 PolarHBondContact O-N 3.46Å; L373-F375 PolarHBondContact O-N 3.17Å; F375-D377 VanDerWaalsContact C-N 3.28Å; F375-D377 PolarHBondContact O-N 3.49Å; F375-A378 PolarHBondContact O-N 2.94Å; F375-F379 AromaticContact CD2-CD2 3.61Å; F375-F379 HydrophobicContact CD2-CD2 3.61Å; F375-F379 AromaticContact CD2-CE2 3.35Å; F375-F379 HydrophobicContact CD2-CE2 3.35Å; F375-F379 HydrophobicContact CD2-CZ 4.3Å; F375-F379 AromaticContact CE2-CD2 3.42Å; F375-F379 HydrophobicContact CE2-CD2 3.42Å; F375-F379 VanDerWaalsContact CE2-CD2 3.42Å; F375-F379 HydrophobicContact CE2-CE1 4.39Å; F375-F379 AromaticContact CE2-CE2 2.98Å; F375-F379 HydrophobicContact CE2-CE2 2.98Å; F375-F379 HydrophobicContact CE2-CG 4.28Å; F375-F379 AromaticContact CE2-CZ 3.53Å; F375-F379 HydrophobicContact CE2-CZ 3.53Å; F375-F379 HydrophobicContact CG-CD2 4.27Å; F375-F379 HydrophobicContact CG-CE2 4.41Å; F375-F379 AromaticContact CZ-CD2 3.95Å; F375-F379 HydrophobicContact CZ-CD2 3.95Å; F375-F379 AromaticContact CZ-CE2 3.85Å; F375-F379 HydrophobicContact CZ-CE2 3.85Å; F375-F379 HydrophobicContact CZ-CG 4.43Å; F375-F379 HydrophobicContact CZ-CZ 4.2Å; F375-F379 VanDerWaalsContact O-CD2 3.27Å; F375-F379 WeakPolarHBondContact O-CD2 3.37Å; F375-F379 PolarHBondContact O-N 2.82Å; F375-H488 AromaticContact CE1-CD2 3.45Å; F375-H488 VanDerWaalsContact CE1-CD2 3.45Å; F375-H488 WeakPolarHBondContact CE1-CD2 3.22Å; F375-H488 AromaticContact CE1-NE2 3.39Å; F375-H488 WeakPolarHBondContact CE1-NE2 3.33Å; F375-H488 HydrophobicContact CZ-CB 4.21Å; F375-H488 AromaticContact CZ-CD2 3.26Å; F375-H488 WeakPolarHBondContact CZ-CD2 3.04Å; F375-H488 AromaticContact CZ-CG 3.7Å; F375-H488 AromaticContact CZ-NE2 3.71Å; F375-H488 WeakPolarHBondContact CZ-O 3.07Å; F375-A491 HydrophobicContact CD2-CB 3.96Å; F375-A491 HydrophobicContact CE2-CB 3.18Å; F375-A491 HydrophobicContact CZ-CB 3.74Å; F375-L495 HydrophobicContact CB-CD1 4.44Å; F375-L495 HydrophobicContact CD1-CD1 4.25Å; F375-L495 HydrophobicContact CG-CD1 4.31Å
376L86.8Confident87Confident77 Ų7762.9 Ų62.940%0.40336%0.357SS..Hα-helixtrans-58.8-40.4176.5-73.8167.6000112.2R372 L373 Q380R372-L376 WeakPolarHBondContact O-CG 3.39Å; R372-L376 PolarHBondContact O-N 3.1Å; L373-L376 PolarHBondContact O-N 3.14Å; L373-L376 VanDerWaalsContact O-N 3.14Å; L376-Q380 WeakPolarHBondContact O-CG 3.27Å; L376-Q380 PolarHBondContact O-N 2.7Å
377D85.3Confident86.9Confident98 Ų9860.4 Ų60.452%0.52434%0.337SS..Hα-helixtrans-67-45.3178.7-66.2-20.9000111.6L373 F375 F379 Q380 E381L373-D377 PolarHBondContact O-N 2.66Å; F375-D377 VanDerWaalsContact C-N 3.28Å; F375-D377 PolarHBondContact O-N 3.49Å; D377-F379 PolarHBondContact O-N 3.44Å; D377-Q380 PolarHBondContact O-N 2.82Å; D377-E381 PolarHBondContact O-N 2.74Å
378A84.4Confident86.8Confident16 Ų1659 Ų5913%0.13233%0.325CS..Hα-helixtrans-65.7-24.1-178.100000114.2Q374 F375 C390Q374-A378 WeakPolarHBondContact O-CB 2.82Å; Q374-A378 PolarHBondContact O-N 3.1Å; Q374-A378 VanDerWaalsContact O-N 3.12Å; F375-A378 PolarHBondContact O-N 2.94Å; A378-C390 HydrophobicContact CB-CB 3.53Å; A378-C390 VanDerWaalsContact CB-SG 3.52Å
379F85.9Confident86.6Confident33 Ų3361.6 Ų61.615%0.14535%0.348CS..THydrogen-bonded Turntrans-91.8-4.3176.5-80.1-98.3000113.4F375 D377 I484 L487 H488F375-F379 AromaticContact CD2-CD2 3.61Å; F375-F379 HydrophobicContact CD2-CD2 3.61Å; F375-F379 AromaticContact CD2-CE2 3.35Å; F375-F379 HydrophobicContact CD2-CE2 3.35Å; F375-F379 HydrophobicContact CD2-CZ 4.3Å; F375-F379 AromaticContact CE2-CD2 3.42Å; F375-F379 HydrophobicContact CE2-CD2 3.42Å; F375-F379 VanDerWaalsContact CE2-CD2 3.42Å; F375-F379 HydrophobicContact CE2-CE1 4.39Å; F375-F379 AromaticContact CE2-CE2 2.98Å; F375-F379 HydrophobicContact CE2-CE2 2.98Å; F375-F379 HydrophobicContact CE2-CG 4.28Å; F375-F379 AromaticContact CE2-CZ 3.53Å; F375-F379 HydrophobicContact CE2-CZ 3.53Å; F375-F379 HydrophobicContact CG-CD2 4.27Å; F375-F379 HydrophobicContact CG-CE2 4.41Å; F375-F379 AromaticContact CZ-CD2 3.95Å; F375-F379 HydrophobicContact CZ-CD2 3.95Å; F375-F379 AromaticContact CZ-CE2 3.85Å; F375-F379 HydrophobicContact CZ-CE2 3.85Å; F375-F379 HydrophobicContact CZ-CG 4.43Å; F375-F379 HydrophobicContact CZ-CZ 4.2Å; F375-F379 VanDerWaalsContact O-CD2 3.27Å; F375-F379 WeakPolarHBondContact O-CD2 3.37Å; F375-F379 PolarHBondContact O-N 2.82Å; D377-F379 PolarHBondContact O-N 3.44Å; F379-I484 HydrophobicContact CD1-CG2 3.7Å; F379-I484 HydrophobicContact CE1-CG2 4.02Å; F379-I484 WeakPolarHBondContact CE1-O 3.32Å; F379-L487 HydrophobicContact CE1-CB 4.16Å; F379-L487 HydrophobicContact CZ-CB 4.15Å; F379-H488 HydrophobicContact CD1-CB 3.68Å; F379-H488 AromaticContact CD1-CD2 3.82Å; F379-H488 HydrophobicContact CE1-CB 3.51Å; F379-H488 AromaticContact CG-CD2 3.88Å; F379-H488 HydrophobicContact CZ-CB 4.25Å
380Q83.6Confident86.5Confident153 Ų15355.6 Ų55.672%0.71533%0.327SS*.THydrogen-bonded Turntrans-89.2-20.5167.5-70.9176.51700112.4L376 D377L376-Q380 WeakPolarHBondContact O-CG 3.27Å; L376-Q380 PolarHBondContact O-N 2.7Å; D377-Q380 PolarHBondContact O-N 2.82Å
381E77.8Confident86.7Confident119 Ų11952.9 Ų52.956%0.55631%0.305SS*.SBendtrans-67.8135.8176.3-69.5-164.3162.600111.3D377 G383 A386D377-E381 PolarHBondContact O-N 2.74Å; E381-G383 PolarHBondContact O-N 2.85Å; E381-A386 HydrophobicContact CB-CB 4.04Å; E381-A386 WeakPolarHBondContact OE2-CB 3.47Å
382P76.6Confident86.8Confident130 Ų13057.8 Ų57.884%0.84432%0.322SS*.SBendtrans-70.1129.2176.127.8-32.1000110.4
383G80.5Confident86.9Confident29 Ų2958.7 Ų58.730%0.29933%0.33SS..SBendtrans109.7141.1172.300000114.2E381 G385 E480E381-G383 PolarHBondContact O-N 2.85Å; G383-G385 VanDerWaalsContact C-N 3.26Å; G383-G385 PolarHBondContact O-N 3.1Å; G383-E480 WeakPolarHBondContact CA-OE1 3.32Å
384L86.4Confident87.2Confident18 Ų1854.3 Ų54.39%0.09431%0.306CS..Hα-helixtrans-60.2-29.6-176.9-167.162.9000114.6A386 S387 I388 V468 V474 E480 M483 I484 L487L384-A386 PolarHBondContact O-N 3.33Å; L384-S387 PolarHBondContact O-N 3.42Å; L384-I388 HydrophobicContact CD2-CD1 4.35Å; L384-I388 HydrophobicContact CG-CD1 3.95Å; L384-I388 HydrophobicContact CG-CG1 4.24Å; L384-I388 WeakPolarHBondContact O-CG1 3.37Å; L384-I388 PolarHBondContact O-N 2.88Å; L384-V468 HydrophobicContact CD1-CG1 3.81Å; L384-V468 HydrophobicContact CD2-CG1 3.57Å; L384-V468 HydrophobicContact CG-CG1 3.84Å; L384-V474 HydrophobicContact CD2-CG2 4.31Å; L384-E480 HydrophobicContact CB-CG 4.02Å; L384-E480 PolarHBondContact N-OE1 3.24Å; L384-M483 HydrophobicContact CD1-CB 3.93Å; L384-M483 HydrophobicContact CD2-SD 4.06Å; L384-I484 HydrophobicContact CD1-CG1 3.64Å; L384-L487 HydrophobicContact CD1-CD1 4.3Å
385G87Confident87.6Confident52 Ų5251.3 Ų51.354%0.53629%0.294SS..Hα-helixtrans-61.3-41.2-174.500000114G383 I388 A389G383-G385 VanDerWaalsContact C-N 3.26Å; G383-G385 PolarHBondContact O-N 3.1Å; G385-I388 PolarHBondContact O-N 3.46Å; G385-A389 WeakPolarHBondContact O-CB 3.3Å; G385-A389 PolarHBondContact O-N 2.93Å
386A86.7Confident87.9Confident26 Ų2654 Ų5422%0.21531%0.312CS..Hα-helixtrans-64.9-43.3177.400000111.3E381 L384 A389 C390E381-A386 HydrophobicContact CB-CB 4.04Å; E381-A386 WeakPolarHBondContact OE2-CB 3.47Å; L384-A386 PolarHBondContact O-N 3.33Å; A386-A389 PolarHBondContact O-N 3.31Å; A386-C390 VanDerWaalsContact O-CB 3.3Å; A386-C390 WeakPolarHBondContact O-CB 3.36Å; A386-C390 PolarHBondContact O-N 3.17Å
387S89.8Confident88.2Confident1 Ų152.5 Ų52.51%0.00731%0.307CS..Hα-helixtrans-62.7-44.4177-49.50000112.2L384 C390 C391L384-S387 PolarHBondContact O-N 3.42Å; S387-C390 PolarHBondContact O-N 3.41Å; S387-C391 WeakPolarHBondContact O-CB 3.41Å; S387-C391 PolarHBondContact O-N 3.38Å; S387-C391 PolarHBondContact O-SG 3.17Å
388I90.9Very high88.7Confident21 Ų2147.8 Ų47.811%0.10828%0.282CS..Hα-helixtrans-60.4-50176-66.4169.3000110.7L384 G385 C390 C391 R392 V465 V468 S469 L487L384-I388 HydrophobicContact CD2-CD1 4.35Å; L384-I388 HydrophobicContact CG-CD1 3.95Å; L384-I388 HydrophobicContact CG-CG1 4.24Å; L384-I388 WeakPolarHBondContact O-CG1 3.37Å; L384-I388 PolarHBondContact O-N 2.88Å; G385-I388 PolarHBondContact O-N 3.46Å; I388-C390 VanDerWaalsContact C-N 3.31Å; I388-C390 PolarHBondContact O-N 2.83Å; I388-C391 PolarHBondContact O-N 3.45Å; I388-R392 PolarHBondContact O-N 2.91Å; I388-V465 HydrophobicContact CG2-CG1 4.35Å; I388-V468 HydrophobicContact CD1-CG1 3.85Å; I388-V468 HydrophobicContact CG1-CG1 3.98Å; I388-S469 WeakPolarHBondContact CG2-OG 3.45Å; I388-L487 HydrophobicContact CG1-CD1 4.26Å
389A90.3Very high89.3Confident60 Ų6051.5 Ų51.550%0.49630%0.298SS..Hα-helixtrans-60.2-43.4-179.100000111.4G385 A386 R392 Q393G385-A389 WeakPolarHBondContact O-CB 3.3Å; G385-A389 PolarHBondContact O-N 2.93Å; A386-A389 PolarHBondContact O-N 3.31Å; A389-R392 PolarHBondContact O-N 3.24Å; A389-Q393 PolarHBondContact O-N 2.82Å; A389-Q393 VanDerWaalsContact O-N 3.08Å
390C91.6Very high89.7Confident13 Ų1357 Ų579%0.08832%0.322CS..Hα-helixtrans-59.8-49.5174.6-176.70000111.9A378 A386 S387 I388 R392 Q393 L394A378-C390 HydrophobicContact CB-CB 3.53Å; A378-C390 VanDerWaalsContact CB-SG 3.52Å; A386-C390 VanDerWaalsContact O-CB 3.3Å; A386-C390 WeakPolarHBondContact O-CB 3.36Å; A386-C390 PolarHBondContact O-N 3.17Å; S387-C390 PolarHBondContact O-N 3.41Å; I388-C390 VanDerWaalsContact C-N 3.31Å; I388-C390 PolarHBondContact O-N 2.83Å; C390-R392 VanDerWaalsContact C-N 3.34Å; C390-R392 PolarHBondContact O-N 2.88Å; C390-Q393 WeakPolarHBondContact O-CB 3.48Å; C390-Q393 PolarHBondContact O-N 3.02Å; C390-L394 WeakPolarHBondContact O-CB 3.44Å; C390-L394 PolarHBondContact O-N 2.93Å
391C94Very high90.3Very high0 Ų050.5 Ų50.50%029%0.292CS..Hα-helixtrans-62.7-37.5179.1-70.50000112.8S387 I388 L394 V395 L461 V465S387-C391 WeakPolarHBondContact O-CB 3.41Å; S387-C391 PolarHBondContact O-N 3.38Å; S387-C391 PolarHBondContact O-SG 3.17Å; I388-C391 PolarHBondContact O-N 3.45Å; C391-L394 WeakPolarHBondContact O-CB 3.31Å; C391-L394 PolarHBondContact O-N 3.27Å; C391-V395 WeakPolarHBondContact O-CG2 3.49Å; C391-V395 PolarHBondContact O-N 3.38Å; C391-L461 HydrophobicContact CB-CD1 4.11Å; C391-V465 HydrophobicContact CB-CG2 3.38Å
392R93.6Very high91.2Very high115 Ų11545.9 Ų45.943%0.43427%0.271SS..Hα-helixtrans-61.9-43.7173.3-77.2-176.4164.9147.7-2.7112I388 A389 C390 L394 V395 S396 V465 E466 S469I388-R392 PolarHBondContact O-N 2.91Å; A389-R392 PolarHBondContact O-N 3.24Å; C390-R392 VanDerWaalsContact C-N 3.34Å; C390-R392 PolarHBondContact O-N 2.88Å; R392-L394 VanDerWaalsContact C-N 3.34Å; R392-V395 PolarHBondContact O-N 2.89Å; R392-S396 PolarHBondContact O-N 3.45Å; R392-V465 HydrophobicContact CG-CG1 3.45Å; R392-V465 VanDerWaalsContact CG-CG1 3.45Å; R392-E466 IonicContact CZ-OE1 2.79Å; R392-E466 IonicContact NE-OE1 2.61Å; R392-E466 PolarHBondContact NE-OE1 2.74Å; R392-E466 IonicContact NH2-OE1 3.3Å; R392-E466 PolarHBondContact NH2-OE1 2.97Å; R392-E466 IonicContact NH2-OE2 3.76Å; R392-S469 PolarHBondContact NH2-OG 2.82Å; R392-S469 VanDerWaalsContact NH2-OG 3.08Å
393Q92.6Very high92Very high94 Ų9441.6 Ų41.644%0.43925%0.25SS..Hα-helixtrans-64-41.3175.1-175.6178.8-3.900111.4A389 C390 V395 S396 T397A389-Q393 PolarHBondContact O-N 2.82Å; A389-Q393 VanDerWaalsContact O-N 3.08Å; C390-Q393 WeakPolarHBondContact O-CB 3.48Å; C390-Q393 PolarHBondContact O-N 3.02Å; Q393-V395 PolarHBondContact O-N 3.33Å; Q393-S396 PolarHBondContact O-N 3.12Å; Q393-T397 WeakPolarHBondContact O-CB 3.27Å; Q393-T397 PolarHBondContact O-N 2.89Å; Q393-T397 PolarHBondContact O-OG1 3.29Å
394L94.2Very high92.7Very high4 Ų443.1 Ų43.12%0.02126%0.256CS..Hα-helixtrans-57.5-48176.4174.359.4000111.1L371 C390 C391 R392 S396 T397 A398 L461 A491 L495L371-L394 HydrophobicContact CD1-CD1 4.01Å; L371-L394 HydrophobicContact CD2-CD1 3.63Å; L371-L394 HydrophobicContact CG-CD1 3.93Å; C390-L394 WeakPolarHBondContact O-CB 3.44Å; C390-L394 PolarHBondContact O-N 2.93Å; C391-L394 WeakPolarHBondContact O-CB 3.31Å; C391-L394 PolarHBondContact O-N 3.27Å; R392-L394 VanDerWaalsContact C-N 3.34Å; L394-S396 PolarHBondContact O-N 2.82Å; L394-T397 PolarHBondContact O-N 3.4Å; L394-A398 HydrophobicContact CD1-CB 4.45Å; L394-A398 WeakPolarHBondContact O-CB 3.49Å; L394-A398 PolarHBondContact O-N 3.01Å; L394-L461 HydrophobicContact CD2-CD2 3.82Å; L394-L461 HydrophobicContact CG-CD2 4.17Å; L394-A491 HydrophobicContact CD2-CB 3.47Å; L394-A491 VanDerWaalsContact CD2-CB 3.47Å; L394-L495 HydrophobicContact CD1-CD2 3.75Å; L394-L495 HydrophobicContact CD1-CG 4.34Å
395V94.3Very high93.1Very high16 Ų1642.4 Ų42.410%0.09725%0.252CS..Hα-helixtrans-54.5-51.1177.8169.80000111.4C391 R392 Q393 T397 I399 L458 L461C391-V395 WeakPolarHBondContact O-CG2 3.49Å; C391-V395 PolarHBondContact O-N 3.38Å; R392-V395 PolarHBondContact O-N 2.89Å; Q393-V395 PolarHBondContact O-N 3.33Å; V395-T397 VanDerWaalsContact C-N 3.33Å; V395-T397 PolarHBondContact O-N 3.11Å; V395-I399 HydrophobicContact CG1-CD1 4.16Å; V395-I399 VanDerWaalsContact O-CG1 3.31Å; V395-I399 WeakPolarHBondContact O-CG1 3.31Å; V395-I399 PolarHBondContact O-N 3.45Å; V395-L458 HydrophobicContact CB-CD1 4.29Å; V395-L458 HydrophobicContact CG1-CD1 4.08Å; V395-L458 HydrophobicContact CG2-CD1 4.16Å; V395-L461 HydrophobicContact CG2-CD2 3.79Å; V395-L461 HydrophobicContact CG2-CG 4.06Å
396S93.6Very high93.5Very high58 Ų5841.6 Ų41.641%0.40624%0.236SC..Hα-helixtrans-63.3-39.9-180-172.20000112.5R392 Q393 L394 K400R392-S396 PolarHBondContact O-N 3.45Å; Q393-S396 PolarHBondContact O-N 3.12Å; L394-S396 PolarHBondContact O-N 2.82Å; S396-K400 WeakPolarHBondContact O-CG 3.42Å; S396-K400 PolarHBondContact O-N 2.87Å
397T94.1Very high93.7Very high46 Ų4642.7 Ų42.728%0.28225%0.249SC..Hα-helixtrans-73.8-40.2-176.9-53.60000111.2L371 Q393 L394 V395 K400 L401L371-T397 HydrophobicContact CD1-CG2 4.15Å; L371-T397 HydrophobicContact CD2-CG2 4.33Å; Q393-T397 WeakPolarHBondContact O-CB 3.27Å; Q393-T397 PolarHBondContact O-N 2.89Å; Q393-T397 PolarHBondContact O-OG1 3.29Å; L394-T397 PolarHBondContact O-N 3.4Å; V395-T397 VanDerWaalsContact C-N 3.33Å; V395-T397 PolarHBondContact O-N 3.11Å; T397-K400 PolarHBondContact O-N 3.45Å; T397-L401 VanDerWaalsContact O-CB 3.31Å; T397-L401 WeakPolarHBondContact O-CB 3.44Å; T397-L401 PolarHBondContact O-N 2.89Å
398A95.1Very high93.8Very high0 Ų044.9 Ų44.90%026%0.259CS..Hα-helixtrans-60.6-45176.500000111.7L394 K400 L401 H402 F454 L458 V494 L498L394-A398 HydrophobicContact CD1-CB 4.45Å; L394-A398 WeakPolarHBondContact O-CB 3.49Å; L394-A398 PolarHBondContact O-N 3.01Å; A398-K400 PolarHBondContact O-N 2.79Å; A398-L401 PolarHBondContact O-N 3.49Å; A398-H402 VanDerWaalsContact O-CB 3.23Å; A398-H402 WeakPolarHBondContact O-CB 3.29Å; A398-H402 PolarHBondContact O-N 3.35Å; A398-F454 HydrophobicContact CB-CE2 4.15Å; A398-F454 HydrophobicContact CB-CZ 4.09Å; A398-L458 HydrophobicContact CB-CD1 4.23Å; A398-V494 HydrophobicContact CB-CG1 3.87Å; A398-L498 HydrophobicContact CB-CD1 3.84Å
399I95.9Very high93.8Very high93 Ų9344.4 Ų44.448%0.47726%0.256SS..Hα-helixtrans-58.9-48.5176-67.3165.6000110.9V395 L401 G403 L458V395-I399 HydrophobicContact CG1-CD1 4.16Å; V395-I399 VanDerWaalsContact O-CG1 3.31Å; V395-I399 WeakPolarHBondContact O-CG1 3.31Å; V395-I399 PolarHBondContact O-N 3.45Å; I399-L401 VanDerWaalsContact C-N 3.34Å; I399-L401 PolarHBondContact O-N 3.37Å; I399-G403 PolarHBondContact O-N 3.11Å; I399-L458 HydrophobicContact CD1-CD2 4.02Å; I399-L458 HydrophobicContact CG1-CD2 3.53Å
400K95.7Very high93.6Very high148 Ų14845 Ų4564%0.64326%0.261SS*.Hα-helixtrans-62.2-42.9179.1-70.2172.2-176.51690111.4S396 T397 A398 S404S396-K400 WeakPolarHBondContact O-CG 3.42Å; S396-K400 PolarHBondContact O-N 2.87Å; T397-K400 PolarHBondContact O-N 3.45Å; A398-K400 PolarHBondContact O-N 2.79Å; K400-S404 WeakPolarHBondContact O-CB 3.47Å; K400-S404 PolarHBondContact O-N 2.94Å
401L95.2Very high93.3Very high18 Ų1853.4 Ų53.49%0.09430%0.299CS..Hα-helixtrans-70.3-42.9-178.3-168.457.5000111.9T364 L368 T397 A398 I399 G403 S404 I405 L498T364-L401 HydrophobicContact CG2-CD1 3.99Å; L368-L401 HydrophobicContact CD2-CD2 3.41Å; L368-L401 VanDerWaalsContact CD2-CD2 3.41Å; L368-L401 HydrophobicContact CD2-CG 4.5Å; L368-L401 HydrophobicContact CG-CD2 3.87Å; T397-L401 VanDerWaalsContact O-CB 3.31Å; T397-L401 WeakPolarHBondContact O-CB 3.44Å; T397-L401 PolarHBondContact O-N 2.89Å; A398-L401 PolarHBondContact O-N 3.49Å; I399-L401 VanDerWaalsContact C-N 3.34Å; I399-L401 PolarHBondContact O-N 3.37Å; L401-G403 PolarHBondContact O-N 3.33Å; L401-S404 WeakPolarHBondContact O-CB 3.21Å; L401-S404 PolarHBondContact O-N 3.36Å; L401-S404 VanDerWaalsContact O-N 3.16Å; L401-I405 HydrophobicContact CG-CD1 4.13Å; L401-I405 VanDerWaalsContact O-CG1 3.27Å; L401-I405 WeakPolarHBondContact O-CG1 3.41Å; L401-I405 PolarHBondContact O-N 2.86Å; L401-L498 HydrophobicContact CD2-CD1 4.47Å
402H96.5Very high93Very high22 Ų2254.1 Ų54.110%0.10230%0.304CS..Hα-helixtrans-56.2-49.9172.7-178.2-102.6000111.3A398 S404 I405 L406 F454 L498 L501A398-H402 VanDerWaalsContact O-CB 3.23Å; A398-H402 WeakPolarHBondContact O-CB 3.29Å; A398-H402 PolarHBondContact O-N 3.35Å; H402-S404 VanDerWaalsContact C-N 3.32Å; H402-S404 PolarHBondContact O-N 2.91Å; H402-I405 PolarHBondContact O-N 3.13Å; H402-L406 VanDerWaalsContact CE1-CD1 3.4Å; H402-L406 WeakPolarHBondContact CE1-CD1 3.32Å; H402-L406 WeakPolarHBondContact O-CG 3.46Å; H402-L406 PolarHBondContact O-N 3.37Å; H402-F454 HydrophobicContact CB-CD1 4.28Å; H402-F454 HydrophobicContact CB-CE1 3.67Å; H402-F454 HydrophobicContact CB-CE2 4.3Å; H402-F454 HydrophobicContact CB-CZ 3.68Å; H402-F454 AromaticContact CD2-CD1 3.54Å; H402-F454 AromaticContact CD2-CE1 3.86Å; H402-F454 AromaticContact CD2-CG 3.74Å; H402-F454 AromaticContact CE1-CD1 3.88Å; H402-F454 AromaticContact CG-CD1 3.67Å; H402-F454 AromaticContact CG-CE1 3.52Å; H402-F454 AromaticContact CG-CZ 3.99Å; H402-F454 AromaticContact ND1-CD1 3.88Å; H402-F454 AromaticContact ND1-CE1 3.82Å; H402-F454 AromaticContact NE2-CD1 3.74Å; H402-L498 HydrophobicContact CB-CD2 3.79Å; H402-L501 WeakPolarHBondContact CD2-CD2 3.38Å
403G94.9Very high92.5Very high40 Ų4050.5 Ų50.541%0.41230%0.302SS..Hα-helixtrans-60.4-39.4175.300000112.9I399 L401 G407I399-G403 PolarHBondContact O-N 3.11Å; L401-G403 PolarHBondContact O-N 3.33Å; G403-G407 PolarHBondContact O-N 3.44Å
404S94.5Very high92.2Very high61 Ų6152.8 Ų52.843%0.42732%0.318SS..Hα-helixtrans-64.6-44.7175.6-173.60000112.5K400 L401 H402 G407 Q408K400-S404 WeakPolarHBondContact O-CB 3.47Å; K400-S404 PolarHBondContact O-N 2.94Å; L401-S404 WeakPolarHBondContact O-CB 3.21Å; L401-S404 PolarHBondContact O-N 3.36Å; L401-S404 VanDerWaalsContact O-N 3.16Å; H402-S404 VanDerWaalsContact C-N 3.32Å; H402-S404 PolarHBondContact O-N 2.91Å; S404-G407 PolarHBondContact O-N 3.29Å; S404-Q408 WeakPolarHBondContact O-CG 3.28Å; S404-Q408 PolarHBondContact O-N 3.42Å; S404-Q408 VanDerWaalsContact O-N 3.1Å
405I95.3Very high91.9Very high2 Ų258.3 Ų58.31%0.0134%0.341CS..Hα-helixtrans-58.5-51177.6-72.8162000110.5T364 L401 H402 Q408 L498 L501 H502 L505T364-I405 HydrophobicContact CG2-CD1 3.9Å; T364-I405 HydrophobicContact CG2-CG1 3.53Å; L401-I405 HydrophobicContact CG-CD1 4.13Å; L401-I405 VanDerWaalsContact O-CG1 3.27Å; L401-I405 WeakPolarHBondContact O-CG1 3.41Å; L401-I405 PolarHBondContact O-N 2.86Å; H402-I405 PolarHBondContact O-N 3.13Å; I405-Q408 WeakPolarHBondContact O-CB 3.14Å; I405-Q408 PolarHBondContact O-N 2.93Å; I405-L498 HydrophobicContact CD1-CD2 4.34Å; I405-L501 HydrophobicContact CB-CD2 4.35Å; I405-L501 HydrophobicContact CG2-CD2 3.8Å; I405-L501 HydrophobicContact CG2-CG 3.79Å; I405-H502 HydrophobicContact CD1-CB 4.28Å; I405-L505 HydrophobicContact CG2-CD1 3.37Å
406L94.1Very high91.8Very high36 Ų3657.9 Ų57.919%0.18834%0.339CS..Hα-helixtrans-64.9-41.7177.9-66.8-179.1000111.8H402 Q408 F409 A410 L447 L501H402-L406 VanDerWaalsContact CE1-CD1 3.4Å; H402-L406 WeakPolarHBondContact CE1-CD1 3.32Å; H402-L406 WeakPolarHBondContact O-CG 3.46Å; H402-L406 PolarHBondContact O-N 3.37Å; L406-Q408 PolarHBondContact O-N 3.46Å; L406-F409 CarbonylContact O-C 3.34Å; L406-F409 PolarHBondContact O-N 3.48Å; L406-A410 PolarHBondContact O-N 3.34Å; L406-L447 HydrophobicContact CD2-CD1 3.67Å; L406-L501 HydrophobicContact CD2-CD1 4.15Å; L406-L501 HydrophobicContact CD2-CD2 4.16Å; L406-L501 HydrophobicContact CG-CD2 4.36Å
407G92.4Very high91.7Very high48 Ų4857.6 Ų57.650%0.49533%0.332SS..Hα-helixtrans-58.2-31.7178.800000113.2G403 S404 F409 A410G403-G407 PolarHBondContact O-N 3.44Å; S404-G407 PolarHBondContact O-N 3.29Å; G407-F409 PolarHBondContact O-N 3.48Å; G407-F409 VanDerWaalsContact O-N 3.17Å; G407-A410 PolarHBondContact O-N 3.24Å
408Q90.9Very high91.7Very high48 Ų4857.5 Ų57.522%0.22434%0.337CS..THydrogen-bonded Turntrans-60.7-25.3174.8-71172.649.600112.7K357 T364 S404 I405 L406K357-Q408 PolarHBondContact NZ-O 2.89Å; T364-Q408 PolarHBondContact OG1-NE2 3.46Å; S404-Q408 WeakPolarHBondContact O-CG 3.28Å; S404-Q408 PolarHBondContact O-N 3.42Å; S404-Q408 VanDerWaalsContact O-N 3.1Å; I405-Q408 WeakPolarHBondContact O-CB 3.14Å; I405-Q408 PolarHBondContact O-N 2.93Å; L406-Q408 PolarHBondContact O-N 3.46Å
409F90.5Very high91.6Very high10 Ų1058.3 Ų58.34%0.04434%0.341CS..THydrogen-bonded Turntrans-114.114-176.5-69.9-94000113.8K357 M361 L406 G407 H411 S412 L416 L505 Y509K357-F409 VanDerWaalsContact NZ-CD1 3.29Å; K357-F409 VanDerWaalsContact NZ-CE1 3.28Å; M361-F409 HydrophobicContact CE-CE1 4.2Å; M361-F409 HydrophobicContact CE-CE2 3.81Å; M361-F409 HydrophobicContact CE-CZ 3.25Å; L406-F409 CarbonylContact O-C 3.34Å; L406-F409 PolarHBondContact O-N 3.48Å; G407-F409 PolarHBondContact O-N 3.48Å; G407-F409 VanDerWaalsContact O-N 3.17Å; F409-H411 PolarHBondContact O-N 2.79Å; F409-S412 WeakPolarHBondContact O-CB 3.22Å; F409-S412 PolarHBondContact O-N 3.16Å; F409-L416 HydrophobicContact CB-CD2 3.66Å; F409-L416 HydrophobicContact CD1-CD1 4.11Å; F409-L416 HydrophobicContact CG-CD2 4.35Å; F409-L505 HydrophobicContact CD2-CB 4.11Å; F409-L505 HydrophobicContact CD2-CD1 3.92Å; F409-L505 HydrophobicContact CD2-CD2 4.31Å; F409-L505 HydrophobicContact CD2-CG 4.36Å; F409-L505 HydrophobicContact CE2-CB 3.54Å; F409-L505 HydrophobicContact CE2-CD1 4.11Å; F409-L505 HydrophobicContact CE2-CG 4.28Å; F409-L505 HydrophobicContact CG-CD2 4.41Å; F409-L505 HydrophobicContact CZ-CB 3.78Å; F409-L505 VanDerWaalsContact CZ-O 3.22Å; F409-L505 WeakPolarHBondContact CZ-O 3.45Å; F409-Y509 HydrophobicContact CE1-CD2 4.41Å
410A86.9Confident91.6Very high73 Ų7353.9 Ų53.960%0.60332%0.318SS*.THydrogen-bonded Turntrans-55.9-27.2-17600000114.2L406 G407L406-A410 PolarHBondContact O-N 3.34Å; G407-A410 PolarHBondContact O-N 3.24Å
411H85.4Confident91.6Very high189 Ų18952.2 Ų52.288%0.87531%0.313SS*.THydrogen-bonded Turntrans-81.7-12.1-180-58.3-34.6000114.6F409F409-H411 PolarHBondContact O-N 2.79Å
412S86.4Confident91.6Very high15 Ų1555.7 Ų55.711%0.10533%0.328CS..SBendtrans-77.1-24.9-176.4-610000113.2F409 K415F409-S412 WeakPolarHBondContact O-CB 3.22Å; F409-S412 PolarHBondContact O-N 3.16Å; S412-K415 PolarHBondContact O-N 2.8Å
413G85Confident91.5Very high39 Ų3954.6 Ų54.640%0.40232%0.323SS..THydrogen-bonded Turntrans51.3-145.6179.200000113.6K415 L416G413-K415 PolarHBondContact O-N 3.2Å; G413-L416 VanDerWaalsContact O-CB 3.29Å; G413-L416 WeakPolarHBondContact O-CB 3.47Å; G413-L416 PolarHBondContact O-N 3.39Å
414D86.4Confident91.5Very high143 Ų14353.5 Ų53.577%0.76531%0.309SS*.Hα-helixtrans-55.4-24.4-177.1-51.6-14000114.3L416 D417 A418D414-L416 PolarHBondContact O-N 3.38Å; D414-D417 PolarHBondContact O-N 3.01Å; D414-A418 PolarHBondContact O-N 2.83Å; D414-A418 VanDerWaalsContact O-N 3.12Å
415K87.2Confident91.6Very high119 Ų11955.4 Ų55.452%0.51731%0.314SS..Hα-helixtrans-65.3-30.3176.2-65.7-178.3177.6-178.60111.9S412 G413 L419S412-K415 PolarHBondContact O-N 2.8Å; G413-K415 PolarHBondContact O-N 3.2Å; K415-L419 VanDerWaalsContact O-CB 3.31Å; K415-L419 WeakPolarHBondContact O-CB 3.38Å; K415-L419 PolarHBondContact O-N 2.9Å
416L91.8Very high91.6Very high8 Ų857.6 Ų57.64%0.04232%0.322CS..Hα-helixtrans-69.4-46.4175.5-173.464.7000110.7F409 G413 D414 A418 L419 T420 L447 L505 C508F409-L416 HydrophobicContact CB-CD2 3.66Å; F409-L416 HydrophobicContact CD1-CD1 4.11Å; F409-L416 HydrophobicContact CG-CD2 4.35Å; G413-L416 VanDerWaalsContact O-CB 3.29Å; G413-L416 WeakPolarHBondContact O-CB 3.47Å; G413-L416 PolarHBondContact O-N 3.39Å; D414-L416 PolarHBondContact O-N 3.38Å; L416-A418 PolarHBondContact O-N 3.19Å; L416-L419 PolarHBondContact O-N 3.44Å; L416-L419 VanDerWaalsContact O-N 3.15Å; L416-T420 HydrophobicContact CD1-CG2 4.49Å; L416-T420 HydrophobicContact CG-CG2 4.42Å; L416-T420 WeakPolarHBondContact O-CG2 3.47Å; L416-T420 PolarHBondContact O-N 2.88Å; L416-T420 PolarHBondContact O-OG1 2.99Å; L416-L447 HydrophobicContact CD2-CD2 3.96Å; L416-L447 HydrophobicContact CG-CD2 4.41Å; L416-L505 HydrophobicContact CD1-CD2 3.84Å; L416-L505 HydrophobicContact CD2-CD2 3.95Å; L416-L505 HydrophobicContact CG-CD2 4.2Å; L416-C508 HydrophobicContact CD1-CB 4.05Å
417D92.5Very high91.5Very high51 Ų5156.9 Ų56.927%0.27332%0.318SS..Hα-helixtrans-56.9-53.3179.3-65.8-59.1000110.4D414 L419 T420 E421 L447D414-D417 PolarHBondContact O-N 3.01Å; D417-L419 VanDerWaalsContact C-N 3.26Å; D417-L419 PolarHBondContact O-N 3.13Å; D417-T420 PolarHBondContact O-N 3.17Å; D417-T420 VanDerWaalsContact O-N 3.12Å; D417-T420 PolarHBondContact O-OG1 3.18Å; D417-E421 WeakPolarHBondContact O-CG 3.41Å; D417-E421 PolarHBondContact O-N 3.29Å; D417-L447 WeakPolarHBondContact OD1-CB 3.29Å; D417-L447 VanDerWaalsContact OD1-CD2 3.29Å; D417-L447 WeakPolarHBondContact OD1-CD2 3.31Å
418A92.3Very high91.5Very high45 Ų4558 Ų5837%0.37231%0.312SS..Hα-helixtrans-57.2-38.1177.100000113D414 L416 Q422D414-A418 PolarHBondContact O-N 2.83Å; D414-A418 VanDerWaalsContact O-N 3.12Å; L416-A418 PolarHBondContact O-N 3.19Å; A418-Q422 WeakPolarHBondContact O-CG 3.38Å; A418-Q422 PolarHBondContact O-N 3.12Å; A418-Q422 VanDerWaalsContact O-N 3.08Å
419L93.3Very high91.5Very high16 Ų1661.9 Ų61.98%0.08433%0.33CS..Hα-helixtrans-73.3-36.4179.2-171.964.7000112.3C346 K415 L416 D417 Q422 L423 C508 V511C346-L419 HydrophobicContact CB-CD2 4.39Å; K415-L419 VanDerWaalsContact O-CB 3.31Å; K415-L419 WeakPolarHBondContact O-CB 3.38Å; K415-L419 PolarHBondContact O-N 2.9Å; L416-L419 PolarHBondContact O-N 3.44Å; L416-L419 VanDerWaalsContact O-N 3.15Å; D417-L419 VanDerWaalsContact C-N 3.26Å; D417-L419 PolarHBondContact O-N 3.13Å; L419-Q422 PolarHBondContact O-N 3Å; L419-L423 HydrophobicContact CG-CD1 4.4Å; L419-L423 WeakPolarHBondContact O-CB 3.5Å; L419-L423 WeakPolarHBondContact O-CG 3.49Å; L419-L423 PolarHBondContact O-N 3.19Å; L419-C508 HydrophobicContact CD2-CB 3.85Å; L419-C508 VanDerWaalsContact CD2-O 3.28Å; L419-C508 WeakPolarHBondContact CD2-O 3.17Å; L419-C508 HydrophobicContact CG-CB 4.41Å; L419-V511 HydrophobicContact CD1-CB 4.46Å; L419-V511 HydrophobicContact CD1-CG1 3.84Å
420T95.9Very high91.3Very high1 Ų167.1 Ų67.11%0.00635%0.35CS..Hα-helixtrans-66.2-38.1174.260.60000111.8L416 D417 L423 S424 L447 T504 C508L416-T420 HydrophobicContact CD1-CG2 4.49Å; L416-T420 HydrophobicContact CG-CG2 4.42Å; L416-T420 WeakPolarHBondContact O-CG2 3.47Å; L416-T420 PolarHBondContact O-N 2.88Å; L416-T420 PolarHBondContact O-OG1 2.99Å; D417-T420 PolarHBondContact O-N 3.17Å; D417-T420 VanDerWaalsContact O-N 3.12Å; D417-T420 PolarHBondContact O-OG1 3.18Å; T420-L423 PolarHBondContact O-N 3.09Å; T420-S424 WeakPolarHBondContact O-CB 3.44Å; T420-S424 PolarHBondContact O-N 3.47Å; T420-L447 HydrophobicContact CG2-CB 4.18Å; T420-L447 PolarHBondContact OG1-N 3.07Å; T420-T504 HydrophobicContact CG2-CG2 4.06Å; T420-C508 WeakPolarHBondContact CG2-SG 3.26Å
421E95.9Very high91.2Very high112 Ų11265.5 Ų65.552%0.52333%0.334SS..Hα-helixtrans-62.3-47173.3-71.6179.5175.800111.5D417 L423 S424 L425D417-E421 WeakPolarHBondContact O-CG 3.41Å; D417-E421 PolarHBondContact O-N 3.29Å; E421-L423 VanDerWaalsContact C-N 3.35Å; E421-L423 PolarHBondContact O-N 3.36Å; E421-S424 WeakPolarHBondContact O-CB 3.48Å; E421-S424 PolarHBondContact O-N 3.04Å; E421-L425 WeakPolarHBondContact O-CG 3.5Å; E421-L425 PolarHBondContact O-N 2.71Å
422Q94.8Very high91.2Very high91 Ų9160.2 Ų60.243%0.42532%0.323SS..Hα-helixtrans-60-43.6176.4-75-179.7-0.700112.5A418 L419 L425 W426A418-Q422 WeakPolarHBondContact O-CG 3.38Å; A418-Q422 PolarHBondContact O-N 3.12Å; A418-Q422 VanDerWaalsContact O-N 3.08Å; L419-Q422 PolarHBondContact O-N 3Å; Q422-L425 PolarHBondContact O-N 3.04Å; Q422-W426 HydrophobicContact CB-CH2 4.5Å; Q422-W426 HydrophobicContact CB-CZ2 4.41Å; Q422-W426 PolarHBondContact O-N 3.02Å; Q422-W426 VanDerWaalsContact O-N 3.07Å
423L95.2Very high91Very high0 Ų063 Ų630%035%0.347CS..Hα-helixtrans-63.8-41176.8-79.8166.9000112.3Y241 L242 L419 T420 E421 L425 W426 F427 V444 H507 C508 V511Y241-L423 HydrophobicContact CE2-CD2 3.64Å; L242-L423 HydrophobicContact CD2-CD2 4.43Å; L419-L423 HydrophobicContact CG-CD1 4.4Å; L419-L423 WeakPolarHBondContact O-CB 3.5Å; L419-L423 WeakPolarHBondContact O-CG 3.49Å; L419-L423 PolarHBondContact O-N 3.19Å; T420-L423 PolarHBondContact O-N 3.09Å; E421-L423 VanDerWaalsContact C-N 3.35Å; E421-L423 PolarHBondContact O-N 3.36Å; L423-L425 VanDerWaalsContact C-N 3.34Å; L423-W426 HydrophobicContact CD2-CE3 4.02Å; L423-W426 HydrophobicContact CD2-CZ3 4.19Å; L423-W426 PolarHBondContact O-N 3.05Å; L423-F427 VanDerWaalsContact O-CB 3.29Å; L423-F427 WeakPolarHBondContact O-CB 3.44Å; L423-F427 PolarHBondContact O-N 2.64Å; L423-V444 HydrophobicContact CB-CG1 3.92Å; L423-H507 HydrophobicContact CD1-CB 4.29Å; L423-H507 HydrophobicContact CD2-CB 4.49Å; L423-C508 HydrophobicContact CD1-CB 4.15Å; L423-C508 WeakPolarHBondContact CD1-SG 3.43Å; L423-V511 HydrophobicContact CD2-CG2 3.95Å
424S95.4Very high90.7Very high16 Ų1664.6 Ų64.611%0.11235%0.347CS..Hα-helixtrans-57.2-48.8174.3-168.70000110.6T420 E421 W426 F427 D428 Q445T420-S424 WeakPolarHBondContact O-CB 3.44Å; T420-S424 PolarHBondContact O-N 3.47Å; E421-S424 WeakPolarHBondContact O-CB 3.48Å; E421-S424 PolarHBondContact O-N 3.04Å; S424-W426 PolarHBondContact O-N 2.84Å; S424-F427 PolarHBondContact O-N 3.24Å; S424-D428 VanDerWaalsContact O-CG 3.24Å; S424-D428 PolarHBondContact O-N 2.94Å; S424-Q445 WeakPolarHBondContact OG-CA 3.4Å
425L95.9Very high89.7Confident102 Ų10263.4 Ų63.453%0.53435%0.348SS..Hα-helixtrans-59.7-44.8179.7-70169.6000112.1E421 Q422 L423 Q429E421-L425 WeakPolarHBondContact O-CG 3.5Å; E421-L425 PolarHBondContact O-N 2.71Å; Q422-L425 PolarHBondContact O-N 3.04Å; L423-L425 VanDerWaalsContact C-N 3.34Å; L425-Q429 WeakPolarHBondContact O-CB 3.22Å; L425-Q429 WeakPolarHBondContact O-CG 3.19Å; L425-Q429 PolarHBondContact O-N 3.27Å
426W94.8Very high88.2Confident48 Ų4863.6 Ų63.618%0.18235%0.353CS..Hα-helixtrans-66.8-38.8177.8-63.1-24.7000112.5Y241 L242 P243 L246 Q422 L423 S424 R430 V511Y241-W426 HydrophobicContact CD2-CB 4.13Å; Y241-W426 WeakPolarHBondContact O-CB 3.19Å; L242-W426 HydrophobicContact CD2-CE3 4.03Å; L242-W426 HydrophobicContact CD2-CZ3 4.13Å; P243-W426 HydrophobicContact CG-CD2 4.29Å; P243-W426 HydrophobicContact CG-CH2 4.39Å; P243-W426 HydrophobicContact CG-CZ2 3.99Å; L246-W426 HydrophobicContact CD1-CH2 3.4Å; L246-W426 HydrophobicContact CD1-CZ2 4.16Å; L246-W426 HydrophobicContact CD1-CZ3 3.73Å; Q422-W426 HydrophobicContact CB-CH2 4.5Å; Q422-W426 HydrophobicContact CB-CZ2 4.41Å; Q422-W426 PolarHBondContact O-N 3.02Å; Q422-W426 VanDerWaalsContact O-N 3.07Å; L423-W426 HydrophobicContact CD2-CE3 4.02Å; L423-W426 HydrophobicContact CD2-CZ3 4.19Å; L423-W426 PolarHBondContact O-N 3.05Å; S424-W426 PolarHBondContact O-N 2.84Å; W426-R430 WeakPolarHBondContact O-CB 3.24Å; W426-R430 PolarHBondContact O-N 2.86Å; W426-V511 HydrophobicContact CZ3-CG1 4.28Å
427F92.9Very high86.2Confident20 Ų2072.1 Ų72.19%0.08839%0.393CS..Hα-helixtrans-63.6-45.3176.5-179.9-93000111.9Y241 L423 S424 R430 S431 R443 V444Y241-F427 AromaticContact CD1-CD2 3.82Å; Y241-F427 HydrophobicContact CD1-CD2 3.82Å; Y241-F427 HydrophobicContact CD2-CB 4.03Å; Y241-F427 AromaticContact CE1-CD2 3.94Å; Y241-F427 HydrophobicContact CE1-CD2 3.94Å; Y241-F427 HydrophobicContact CE2-CB 4.21Å; Y241-F427 HydrophobicContact CG-CB 4.28Å; Y241-F427 HydrophobicContact CG-CD2 4.14Å; L423-F427 VanDerWaalsContact O-CB 3.29Å; L423-F427 WeakPolarHBondContact O-CB 3.44Å; L423-F427 PolarHBondContact O-N 2.64Å; S424-F427 PolarHBondContact O-N 3.24Å; F427-R430 PolarHBondContact O-N 2.91Å; F427-S431 WeakPolarHBondContact O-CB 3.09Å; F427-S431 PolarHBondContact O-N 2.87Å; F427-S431 PolarHBondContact O-OG 2.77Å; F427-R443 HydrophobicContact CE1-CB 4.04Å; F427-R443 HydrophobicContact CZ-CB 4.15Å; F427-V444 HydrophobicContact CB-CB 3.9Å; F427-V444 HydrophobicContact CB-CG1 4.28Å; F427-V444 HydrophobicContact CD1-CB 4.17Å; F427-V444 HydrophobicContact CD2-CB 3.73Å; F427-V444 HydrophobicContact CD2-CG2 3.69Å; F427-V444 HydrophobicContact CE2-CB 4.23Å; F427-V444 HydrophobicContact CE2-CG2 3.96Å; F427-V444 HydrophobicContact CG-CB 3.68Å; F427-V444 HydrophobicContact CG-CG2 4.19Å
428D91.8Very high84.4Confident72 Ų7274 Ų7439%0.38540%0.4SS..Hα-helixtrans-66.5-42.9179.3-66.7-28.8000111.4S424 R430 S431 A432S424-D428 VanDerWaalsContact O-CG 3.24Å; S424-D428 PolarHBondContact O-N 2.94Å; D428-R430 VanDerWaalsContact C-N 3.29Å; D428-R430 PolarHBondContact O-N 2.85Å; D428-S431 PolarHBondContact O-N 2.97Å; D428-A432 VanDerWaalsContact O-CB 3.31Å; D428-A432 WeakPolarHBondContact O-CB 3.27Å; D428-A432 PolarHBondContact O-N 2.81Å
429Q90.7Very high82.5Confident129 Ų12978.3 Ų78.360%0.60342%0.424SS*.Hα-helixtrans-58.4-41.8175.1-75.8170.79.800112.1L425 A433L425-Q429 WeakPolarHBondContact O-CB 3.22Å; L425-Q429 WeakPolarHBondContact O-CG 3.19Å; L425-Q429 PolarHBondContact O-N 3.27Å; Q429-A433 PolarHBondContact O-N 3.22Å
430R87.3Confident81.1Confident121 Ų12180.6 Ų80.646%0.45744%0.442SS..Hα-helixtrans-72.4-43.3179.1-171.270.6-162.9-167.87.4112W426 F427 D428 A432 A433 D434W426-R430 WeakPolarHBondContact O-CB 3.24Å; W426-R430 PolarHBondContact O-N 2.86Å; F427-R430 PolarHBondContact O-N 2.91Å; D428-R430 VanDerWaalsContact C-N 3.29Å; D428-R430 PolarHBondContact O-N 2.85Å; R430-A432 VanDerWaalsContact C-N 3.31Å; R430-A432 PolarHBondContact O-N 3Å; R430-A433 WeakPolarHBondContact O-CB 3.49Å; R430-A433 PolarHBondContact O-N 3.1Å; R430-D434 IonicContact CZ-OD1 2.81Å; R430-D434 IonicContact CZ-OD2 3.02Å; R430-D434 IonicContact NE-OD1 3.09Å; R430-D434 IonicContact NE-OD2 3.87Å; R430-D434 PolarHBondContact NE-OD2 2.86Å; R430-D434 IonicContact NH2-OD1 3.44Å; R430-D434 PolarHBondContact NH2-OD1 2.92Å; R430-D434 VanDerWaalsContact NH2-OD1 3.12Å; R430-D434 IonicContact NH2-OD2 3.95Å; R430-D434 PolarHBondContact NH2-OD2 2.94Å; R430-D434 PolarHBondContact O-N 3.42Å
431S84.7Confident80.3Confident39 Ų3982.2 Ų82.227%0.27346%0.458SS..Hα-helixtrans-62.7-39.3178.9-57.80000111.6F427 D428 A433 C435F427-S431 WeakPolarHBondContact O-CB 3.09Å; F427-S431 PolarHBondContact O-N 2.87Å; F427-S431 PolarHBondContact O-OG 2.77Å; D428-S431 PolarHBondContact O-N 2.97Å; S431-A433 VanDerWaalsContact C-N 3.28Å; S431-A433 PolarHBondContact O-N 2.96Å; S431-C435 PolarHBondContact O-N 3.42Å
432A84.5Confident79.9Confident78 Ų7877.8 Ų77.865%0.64544%0.439SS*.Hα-helixtrans-64.8-30.8173.300000113.1D428 R430D428-A432 VanDerWaalsContact O-CB 3.31Å; D428-A432 WeakPolarHBondContact O-CB 3.27Å; D428-A432 PolarHBondContact O-N 2.81Å; R430-A432 VanDerWaalsContact C-N 3.31Å; R430-A432 PolarHBondContact O-N 3Å
433A82.8Confident79.7Confident73 Ų7378 Ų7860%0.60344%0.436SS*.Hα-helixtrans-79.3-36.4178.900000113.1Q429 R430 S431Q429-A433 PolarHBondContact O-N 3.22Å; R430-A433 WeakPolarHBondContact O-CB 3.49Å; R430-A433 PolarHBondContact O-N 3.1Å; S431-A433 VanDerWaalsContact C-N 3.28Å; S431-A433 PolarHBondContact O-N 2.96Å
434D77.7Confident79.6Confident73 Ų7378.1 Ų78.139%0.3944%0.437SS..Hα-helixtrans-84.9-14.2-173.8-71.4-29.7000113.1R430 I436R430-D434 IonicContact CZ-OD1 2.81Å; R430-D434 IonicContact CZ-OD2 3.02Å; R430-D434 IonicContact NE-OD1 3.09Å; R430-D434 IonicContact NE-OD2 3.87Å; R430-D434 PolarHBondContact NE-OD2 2.86Å; R430-D434 IonicContact NH2-OD1 3.44Å; R430-D434 PolarHBondContact NH2-OD1 2.92Å; R430-D434 VanDerWaalsContact NH2-OD1 3.12Å; R430-D434 IonicContact NH2-OD2 3.95Å; R430-D434 PolarHBondContact NH2-OD2 2.94Å; R430-D434 PolarHBondContact O-N 3.42Å; D434-I436 HydrophobicContact CB-CD1 4.18Å; D434-I436 HydrophobicContact CB-CG1 4.47Å; D434-I436 WeakPolarHBondContact O-CG1 3.46Å; D434-I436 PolarHBondContact O-N 3.33Å
435C66.4Low79.6Confident118 Ų11877.4 Ų77.480%0.79743%0.432SS*.  trans51.525.2-179.3-67.90000114.8S431S431-C435 PolarHBondContact O-N 3.42Å
436I55.6Low79.6Confident122 Ų12273.9 Ų73.963%0.62642%0.416SS*.PPolyproline II helixtrans-99120.6-179.2-67.2164000109.1D434 Q438D434-I436 HydrophobicContact CB-CD1 4.18Å; D434-I436 HydrophobicContact CB-CG1 4.47Å; D434-I436 WeakPolarHBondContact O-CG1 3.46Å; D434-I436 PolarHBondContact O-N 3.33Å; I436-Q438 PolarHBondContact O-N 2.85Å
437E50.6Low79.6Confident188 Ų18871.9 Ų71.988%0.87941%0.408SS*.PPolyproline II helixtrans-62.4116.6162.5-74.7-175.8165.100108.7P439E437-P439 WeakPolarHBondContact O-CD 3.46Å
438Q53.5Low79.6Confident89 Ų8975.5 Ų75.542%0.41643%0.425SS..PPolyproline II helixtrans-73.5120.1177.4-73.3-173.83.800110.1I436 S440 V442I436-Q438 PolarHBondContact O-N 2.85Å; Q438-S440 VanDerWaalsContact C-N 3.3Å; Q438-S440 PolarHBondContact O-N 3Å; Q438-V442 PolarHBondContact OE1-O 3.19Å; Q438-V442 VanDerWaalsContact OE1-O 3.09Å
439P52.1Low79.9Confident136 Ų13673.2 Ų73.288%0.88342%0.417SS*.THydrogen-bonded Turntrans-73-16.7-17025.5-32.8000114.6E437E437-P439 WeakPolarHBondContact O-CD 3.46Å
440S64.8Low80.1Confident64 Ų6467.1 Ų67.145%0.44839%0.388SS..THydrogen-bonded Turntrans-95.5-6.3-172.258.40000115.1Q438 V442Q438-S440 VanDerWaalsContact C-N 3.3Å; Q438-S440 PolarHBondContact O-N 3Å; S440-V442 PolarHBondContact O-N 3.36Å
441G79Confident80.5Confident35 Ų3565.6 Ų65.636%0.36138%0.383SS..  trans65.2-8.6-172.900000115.2I496 R497G441-I496 VanDerWaalsContact C-CG2 3.42Å; G441-I496 WeakPolarHBondContact O-CG2 3.32Å; G441-R497 PolarHBondContact O-NH2 2.88Å
442V86.9Confident81.1Confident20 Ų2067.5 Ų67.512%0.12139%0.39CS..  trans-72.4123.9178.4178.40000109.1Q438 S440 I496 E499 S500 L503Q438-V442 PolarHBondContact OE1-O 3.19Å; Q438-V442 VanDerWaalsContact OE1-O 3.09Å; S440-V442 PolarHBondContact O-N 3.36Å; V442-I496 HydrophobicContact CG2-CG2 4.44Å; V442-E499 HydrophobicContact CG2-CB 4.11Å; V442-S500 WeakPolarHBondContact CA-OG 3.26Å; V442-L503 HydrophobicContact CG1-CD2 3.64Å
443R91.1Very high81.7Confident96 Ų9666.1 Ų66.136%0.36237%0.371SS..  trans-134160.7-177.462.7177.4-82.7-163.1-9.5112.8F427 Q445 S500F427-R443 HydrophobicContact CE1-CB 4.04Å; F427-R443 HydrophobicContact CZ-CB 4.15Å; R443-Q445 VanDerWaalsContact NE-OE1 3.09Å; R443-Q445 VanDerWaalsContact NH2-OE1 3.11Å; R443-S500 PolarHBondContact N-OG 2.89Å; R443-S500 VanDerWaalsContact N-OG 3.1Å; R443-S500 VanDerWaalsContact O-CB 3.27Å; R443-S500 WeakPolarHBondContact O-CB 3.34Å
444V93.6Very high82.4Confident1 Ų163 Ų631%0.00634%0.344CS..  trans-97.9134.9171.3179.60000108.4Y241 L423 F427 T504Y241-V444 HydrophobicContact CE1-CG2 4.11Å; Y241-V444 WeakPolarHBondContact OH-CG2 3.4Å; L423-V444 HydrophobicContact CB-CG1 3.92Å; F427-V444 HydrophobicContact CB-CB 3.9Å; F427-V444 HydrophobicContact CB-CG1 4.28Å; F427-V444 HydrophobicContact CD1-CB 4.17Å; F427-V444 HydrophobicContact CD2-CB 3.73Å; F427-V444 HydrophobicContact CD2-CG2 3.69Å; F427-V444 HydrophobicContact CE2-CB 4.23Å; F427-V444 HydrophobicContact CE2-CG2 3.96Å; F427-V444 HydrophobicContact CG-CB 3.68Å; F427-V444 HydrophobicContact CG-CG2 4.19Å; V444-T504 HydrophobicContact CG1-CG2 4.16Å
445Q94.4Very high83.3Confident2 Ų265.4 Ų65.41%0.00935%0.353CS..  trans-156.3171.7-178.951.5-175.7800110.8S424 R443 A449 H450 D453 T504S424-Q445 WeakPolarHBondContact OG-CA 3.4Å; R443-Q445 VanDerWaalsContact NE-OE1 3.09Å; R443-Q445 VanDerWaalsContact NH2-OE1 3.11Å; Q445-A449 HydrophobicContact CB-CB 4.15Å; Q445-A449 HydrophobicContact CG-CB 4.25Å; Q445-H450 WeakPolarHBondContact CG-CE1 3.18Å; Q445-H450 WeakPolarHBondContact CG-ND1 3.26Å; Q445-H450 WeakPolarHBondContact CG-NE2 3.17Å; Q445-H450 PolarHBondContact NE2-ND1 3.47Å; Q445-H450 PolarHBondContact O-CD2 3.32Å; Q445-H450 PolarHBondContact O-NE2 3.22Å; Q445-D453 PolarHBondContact NE2-OD2 2.86Å; Q445-D453 PolarHBondContact OE1-OD2 3.06Å; Q445-T504 WeakPolarHBondContact O-CG2 3.3Å
446S95.8Very high84.8Confident28 Ų2862.6 Ų62.620%0.19634%0.338CS..  trans-62155.8176.969.50000111.6Q448 A449 H450S446-Q448 PolarHBondContact O-N 3Å; S446-A449 PolarHBondContact O-N 3.32Å; S446-A449 WeakPolarHBondContact OG-CB 3.5Å; S446-A449 PolarHBondContact OG-N 2.87Å; S446-H450 PolarHBondContact O-CD2 2.94Å; S446-H450 VanDerWaalsContact O-CD2 3.31Å; S446-H450 PolarHBondContact O-N 3.08Å
447L95.1Very high86.8Confident5 Ų559.8 Ų59.83%0.02632%0.323CS..Hα-helixtrans-59.5-38.7179.3-169.359.5000112.1L406 L416 D417 T420 H450 R451 L501 L505L406-L447 HydrophobicContact CD2-CD1 3.67Å; L416-L447 HydrophobicContact CD2-CD2 3.96Å; L416-L447 HydrophobicContact CG-CD2 4.41Å; D417-L447 WeakPolarHBondContact OD1-CB 3.29Å; D417-L447 VanDerWaalsContact OD1-CD2 3.29Å; D417-L447 WeakPolarHBondContact OD1-CD2 3.31Å; T420-L447 HydrophobicContact CG2-CB 4.18Å; T420-L447 PolarHBondContact OG1-N 3.07Å; L447-H450 PolarHBondContact O-N 3.31Å; L447-R451 WeakPolarHBondContact O-CG 3.38Å; L447-R451 PolarHBondContact O-N 2.85Å; L447-R451 VanDerWaalsContact O-N 3.11Å; L447-L501 HydrophobicContact CD1-CD1 3.84Å; L447-L505 HydrophobicContact CD1-CD2 4.39Å
448Q94.4Very high89Confident96 Ų9651.9 Ų51.945%0.44929%0.286SS..Hα-helixtrans-64.9-45.2177-172.759.532.200111.6S446 H450 R451 D452S446-Q448 PolarHBondContact O-N 3Å; Q448-H450 VanDerWaalsContact C-N 3.31Å; Q448-H450 PolarHBondContact O-N 3.04Å; Q448-R451 WeakPolarHBondContact O-CB 3.44Å; Q448-R451 PolarHBondContact O-N 3.28Å; Q448-R451 VanDerWaalsContact O-N 3.08Å; Q448-D452 PolarHBondContact NE2-OD1 2.07Å; Q448-D452 PolarHBondContact NE2-OD2 3.13Å; Q448-D452 VanDerWaalsContact O-CG 3.27Å; Q448-D452 PolarHBondContact O-N 3.3Å
449A96Very high91Very high24 Ų2450.3 Ų50.320%0.19829%0.288CS..Hα-helixtrans-61.2-39.1176.700000112.2Q445 S446 R451 D452 D453Q445-A449 HydrophobicContact CB-CB 4.15Å; Q445-A449 HydrophobicContact CG-CB 4.25Å; S446-A449 PolarHBondContact O-N 3.32Å; S446-A449 WeakPolarHBondContact OG-CB 3.5Å; S446-A449 PolarHBondContact OG-N 2.87Å; A449-R451 VanDerWaalsContact C-N 3.34Å; A449-R451 PolarHBondContact O-N 2.76Å; A449-D452 PolarHBondContact O-N 2.85Å; A449-D453 WeakPolarHBondContact O-CB 3.33Å; A449-D453 VanDerWaalsContact O-CG 3.23Å; A449-D453 PolarHBondContact O-N 3.37Å
450H96.8Very high93.2Very high2 Ų246 Ų461%0.00926%0.261CS..Hα-helixtrans-61.7-39.9173.4-78.4-60.8000113.1Q445 S446 L447 Q448 F454 S500 L501 T504Q445-H450 WeakPolarHBondContact CG-CE1 3.18Å; Q445-H450 WeakPolarHBondContact CG-ND1 3.26Å; Q445-H450 WeakPolarHBondContact CG-NE2 3.17Å; Q445-H450 PolarHBondContact NE2-ND1 3.47Å; Q445-H450 PolarHBondContact O-CD2 3.32Å; Q445-H450 PolarHBondContact O-NE2 3.22Å; S446-H450 PolarHBondContact O-CD2 2.94Å; S446-H450 VanDerWaalsContact O-CD2 3.31Å; S446-H450 PolarHBondContact O-N 3.08Å; L447-H450 PolarHBondContact O-N 3.31Å; Q448-H450 VanDerWaalsContact C-N 3.31Å; Q448-H450 PolarHBondContact O-N 3.04Å; H450-F454 WeakPolarHBondContact O-CB 3.13Å; H450-F454 PolarHBondContact O-N 3.38Å; H450-S500 PolarHBondContact CE1-O 3.13Å; H450-L501 HydrophobicContact CB-CB 4.37Å; H450-L501 HydrophobicContact CB-CD1 3.84Å; H450-L501 PolarHBondContact CE1-N 3.07Å; H450-T504 PolarHBondContact CE1-OG1 3.49Å; H450-T504 WeakPolarHBondContact NE2-CB 3.33Å; H450-T504 PolarHBondContact NE2-OG1 3.46Å
451R95.5Very high94.7Very high89 Ų8942.9 Ų42.934%0.33624%0.24SC..Hα-helixtrans-65.1-51.1177-71.6176.1-178.5173.93.8110.8L447 Q448 A449 D453 F454 E455L447-R451 WeakPolarHBondContact O-CG 3.38Å; L447-R451 PolarHBondContact O-N 2.85Å; L447-R451 VanDerWaalsContact O-N 3.11Å; Q448-R451 WeakPolarHBondContact O-CB 3.44Å; Q448-R451 PolarHBondContact O-N 3.28Å; Q448-R451 VanDerWaalsContact O-N 3.08Å; A449-R451 VanDerWaalsContact C-N 3.34Å; A449-R451 PolarHBondContact O-N 2.76Å; R451-D453 PolarHBondContact O-N 3.12Å; R451-F454 PolarHBondContact O-N 3Å; R451-E455 WeakPolarHBondContact O-CB 3.23Å; R451-E455 WeakPolarHBondContact O-CG 3.38Å; R451-E455 PolarHBondContact O-N 3.48Å
452D97.4Very high95.4Very high79 Ų7945.8 Ų45.842%0.42224%0.244SC..Hα-helixtrans-61.5-46.8-177.4-62.5-20.3000111Q448 A449 E455 A456Q448-D452 PolarHBondContact NE2-OD1 2.07Å; Q448-D452 PolarHBondContact NE2-OD2 3.13Å; Q448-D452 VanDerWaalsContact O-CG 3.27Å; Q448-D452 PolarHBondContact O-N 3.3Å; A449-D452 PolarHBondContact O-N 2.85Å; D452-E455 PolarHBondContact O-N 3.13Å; D452-A456 WeakPolarHBondContact O-CB 3.46Å; D452-A456 PolarHBondContact O-N 3.08Å
453D96.5Very high95.8Very high48 Ų4848.5 Ų48.526%0.25726%0.26SS..Hα-helixtrans-65.8-42.4178.5-69.4-10000112Q445 A449 R451 A456 E457 R497Q445-D453 PolarHBondContact NE2-OD2 2.86Å; Q445-D453 PolarHBondContact OE1-OD2 3.06Å; A449-D453 WeakPolarHBondContact O-CB 3.33Å; A449-D453 VanDerWaalsContact O-CG 3.23Å; A449-D453 PolarHBondContact O-N 3.37Å; R451-D453 PolarHBondContact O-N 3.12Å; D453-A456 PolarHBondContact O-N 2.69Å; D453-E457 WeakPolarHBondContact O-CG 3.48Å; D453-E457 PolarHBondContact O-N 3.42Å; D453-R497 HydrophobicContact CB-CG 4.36Å; D453-R497 IonicContact OD2-NH1 3.65Å; D453-R497 PolarHBondContact OD2-NH1 3.47Å
454F97.1Very high95.9Very high8 Ų847 Ų474%0.03526%0.257CS..Hα-helixtrans-63.3-44.3179.4173.6-101000111A398 H402 H450 R451 A456 E457 L458 V494 R497 L498A398-F454 HydrophobicContact CB-CE2 4.15Å; A398-F454 HydrophobicContact CB-CZ 4.09Å; H402-F454 HydrophobicContact CB-CD1 4.28Å; H402-F454 HydrophobicContact CB-CE1 3.67Å; H402-F454 HydrophobicContact CB-CE2 4.3Å; H402-F454 HydrophobicContact CB-CZ 3.68Å; H402-F454 AromaticContact CD2-CD1 3.54Å; H402-F454 AromaticContact CD2-CE1 3.86Å; H402-F454 AromaticContact CD2-CG 3.74Å; H402-F454 AromaticContact CE1-CD1 3.88Å; H402-F454 AromaticContact CG-CD1 3.67Å; H402-F454 AromaticContact CG-CE1 3.52Å; H402-F454 AromaticContact CG-CZ 3.99Å; H402-F454 AromaticContact ND1-CD1 3.88Å; H402-F454 AromaticContact ND1-CE1 3.82Å; H402-F454 AromaticContact NE2-CD1 3.74Å; H450-F454 WeakPolarHBondContact O-CB 3.13Å; H450-F454 PolarHBondContact O-N 3.38Å; R451-F454 PolarHBondContact O-N 3Å; F454-A456 VanDerWaalsContact C-N 3.35Å; F454-E457 PolarHBondContact O-N 3.5Å; F454-L458 HydrophobicContact CE1-CD2 3.95Å; F454-L458 HydrophobicContact CZ-CD1 4.43Å; F454-L458 HydrophobicContact CZ-CD2 4.02Å; F454-L458 WeakPolarHBondContact O-CB 3.37Å; F454-L458 PolarHBondContact O-N 2.82Å; F454-V494 HydrophobicContact CE2-CG1 3.99Å; F454-R497 HydrophobicContact CB-CB 4.39Å; F454-R497 HydrophobicContact CD2-CB 4.29Å; F454-L498 HydrophobicContact CD2-CD2 3.97Å; F454-L498 HydrophobicContact CD2-CG 4.14Å; F454-L498 HydrophobicContact CE2-CD1 4.27Å; F454-L498 HydrophobicContact CE2-CD2 3.51Å; F454-L498 HydrophobicContact CE2-CG 3.75Å; F454-L498 HydrophobicContact CZ-CD2 4.15Å
455E97.1Very high95.9Very high123 Ų12347.1 Ų47.158%0.57526%0.257SS*.Hα-helixtrans-61.8-42.4176.2-73.8178.7-169.800111.6R451 D452 A459R451-E455 WeakPolarHBondContact O-CB 3.23Å; R451-E455 WeakPolarHBondContact O-CG 3.38Å; R451-E455 PolarHBondContact O-N 3.48Å; D452-E455 PolarHBondContact O-N 3.13Å; E455-A459 VanDerWaalsContact O-CB 3.27Å; E455-A459 WeakPolarHBondContact O-CB 3.32Å; E455-A459 PolarHBondContact O-N 3.43Å
456A97.4Very high95.8Very high59 Ų5949.9 Ų49.949%0.48827%0.27SS..Hα-helixtrans-63.3-49177.200000112.6D452 D453 F454 A459 S460D452-A456 WeakPolarHBondContact O-CB 3.46Å; D452-A456 PolarHBondContact O-N 3.08Å; D453-A456 PolarHBondContact O-N 2.69Å; F454-A456 VanDerWaalsContact C-N 3.35Å; A456-A459 PolarHBondContact O-N 3.03Å; A456-S460 WeakPolarHBondContact O-CB 3.46Å; A456-S460 PolarHBondContact O-N 3.27Å
457E97Very high95.6Very high64 Ų6453 Ų5330%0.29928%0.284SS..Hα-helixtrans-68.2-37.1-179.9-67.4-58.7165.500112.1D453 F454 S460 L461 A493 V494 R497D453-E457 WeakPolarHBondContact O-CG 3.48Å; D453-E457 PolarHBondContact O-N 3.42Å; F454-E457 PolarHBondContact O-N 3.5Å; E457-S460 WeakPolarHBondContact O-CB 3.15Å; E457-S460 PolarHBondContact O-N 3.44Å; E457-L461 WeakPolarHBondContact O-CB 3.45Å; E457-L461 PolarHBondContact O-N 2.94Å; E457-A493 HydrophobicContact CG-CB 4.15Å; E457-A493 WeakPolarHBondContact OE2-CB 3.4Å; E457-V494 HydrophobicContact CB-CG2 3.92Å; E457-R497 HydrophobicContact CB-CG 4.36Å; E457-R497 HydrophobicContact CG-CG 3.95Å
458L97.3Very high95.2Very high22 Ų2253.5 Ų53.512%0.11529%0.288CS..Hα-helixtrans-66.4-41.7176.2-171.571.8000111.6V395 A398 I399 F454 S460 L461 H462 V494V395-L458 HydrophobicContact CB-CD1 4.29Å; V395-L458 HydrophobicContact CG1-CD1 4.08Å; V395-L458 HydrophobicContact CG2-CD1 4.16Å; A398-L458 HydrophobicContact CB-CD1 4.23Å; I399-L458 HydrophobicContact CD1-CD2 4.02Å; I399-L458 HydrophobicContact CG1-CD2 3.53Å; F454-L458 HydrophobicContact CE1-CD2 3.95Å; F454-L458 HydrophobicContact CZ-CD1 4.43Å; F454-L458 HydrophobicContact CZ-CD2 4.02Å; F454-L458 WeakPolarHBondContact O-CB 3.37Å; F454-L458 PolarHBondContact O-N 2.82Å; L458-S460 VanDerWaalsContact C-N 3.35Å; L458-L461 PolarHBondContact O-N 2.89Å; L458-H462 WeakPolarHBondContact O-CB 3.21Å; L458-H462 PolarHBondContact O-N 2.84Å; L458-V494 HydrophobicContact CD1-CG1 4.27Å
459A96.8Very high94.8Very high55 Ų5550.8 Ų50.846%0.45528%0.279SS..Hα-helixtrans-64.3-40175.100000111.9E455 A456 H462 T463E455-A459 VanDerWaalsContact O-CB 3.27Å; E455-A459 WeakPolarHBondContact O-CB 3.32Å; E455-A459 PolarHBondContact O-N 3.43Å; A456-A459 PolarHBondContact O-N 3.03Å; A459-H462 PolarHBondContact O-N 3.3Å; A459-T463 WeakPolarHBondContact O-CB 3.22Å; A459-T463 PolarHBondContact O-N 3.08Å; A459-T463 PolarHBondContact O-OG1 3.33Å
460S96.9Very high94.2Very high45 Ų4556.3 Ų56.332%0.31530%0.301SS..Hα-helixtrans-60.1-50.1174.11790000111.6A456 E457 L458 T463 K464 S490A456-S460 WeakPolarHBondContact O-CB 3.46Å; A456-S460 PolarHBondContact O-N 3.27Å; E457-S460 WeakPolarHBondContact O-CB 3.15Å; E457-S460 PolarHBondContact O-N 3.44Å; L458-S460 VanDerWaalsContact C-N 3.35Å; S460-T463 PolarHBondContact O-N 2.95Å; S460-K464 WeakPolarHBondContact O-CG 3.2Å; S460-K464 PolarHBondContact O-N 2.93Å; S460-S490 PolarHBondContact OG-OG 3.14Å
461L96.3Very high93.1Very high0 Ų059.2 Ų59.20%032%0.321CS..Hα-helixtrans-59.8-49.4176.3177.461.9000111.6C391 L394 V395 E457 L458 T463 K464 V465 A491 V494C391-L461 HydrophobicContact CB-CD1 4.11Å; L394-L461 HydrophobicContact CD2-CD2 3.82Å; L394-L461 HydrophobicContact CG-CD2 4.17Å; V395-L461 HydrophobicContact CG2-CD2 3.79Å; V395-L461 HydrophobicContact CG2-CG 4.06Å; E457-L461 WeakPolarHBondContact O-CB 3.45Å; E457-L461 PolarHBondContact O-N 2.94Å; L458-L461 PolarHBondContact O-N 2.89Å; L461-T463 VanDerWaalsContact C-N 3.3Å; L461-T463 PolarHBondContact O-N 2.89Å; L461-K464 PolarHBondContact O-N 2.97Å; L461-V465 HydrophobicContact CD1-CG2 4.12Å; L461-V465 HydrophobicContact CG-CG2 4.39Å; L461-V465 VanDerWaalsContact O-CG2 3.3Å; L461-V465 WeakPolarHBondContact O-CG2 3.44Å; L461-V465 PolarHBondContact O-N 3.46Å; L461-A491 HydrophobicContact CD1-CB 4.13Å; L461-A491 HydrophobicContact CD2-CB 4.46Å; L461-V494 HydrophobicContact CB-CG2 4.15Å; L461-V494 HydrophobicContact CD2-CG2 4.01Å
462H94.7Very high91.5Very high96 Ų9662.6 Ų62.644%0.44435%0.346SS..Hα-helixtrans-58.5-43.7-180-173-68.4000111.5L458 A459 V465 E466L458-H462 WeakPolarHBondContact O-CB 3.21Å; L458-H462 PolarHBondContact O-N 2.84Å; A459-H462 PolarHBondContact O-N 3.3Å; H462-V465 PolarHBondContact O-N 3.38Å; H462-E466 WeakPolarHBondContact O-CG 3.29Å; H462-E466 PolarHBondContact O-N 3.26Å
463T95.2Very high89.5Confident76 Ų7666.5 Ų66.547%0.46636%0.361SS..Hα-helixtrans-63.4-44.1178.1-56.20000111.5A459 S460 L461 E466 N467A459-T463 WeakPolarHBondContact O-CB 3.22Å; A459-T463 PolarHBondContact O-N 3.08Å; A459-T463 PolarHBondContact O-OG1 3.33Å; S460-T463 PolarHBondContact O-N 2.95Å; L461-T463 VanDerWaalsContact C-N 3.3Å; L461-T463 PolarHBondContact O-N 2.89Å; T463-E466 PolarHBondContact O-N 2.89Å; T463-N467 WeakPolarHBondContact O-CB 3.21Å; T463-N467 PolarHBondContact O-N 3.5Å; T463-N467 PolarHBondContact O-ND2 2.98Å
464K93.5Very high87.6Confident66 Ų6666.7 Ų66.729%0.28736%0.364SS..Hα-helixtrans-62.1-43.8176.1-74.4-176.9-179.1177.10112.2S460 L461 E466 N467 V468 G486 L487 S490S460-K464 WeakPolarHBondContact O-CG 3.2Å; S460-K464 PolarHBondContact O-N 2.93Å; L461-K464 PolarHBondContact O-N 2.97Å; K464-E466 VanDerWaalsContact C-N 3.34Å; K464-E466 PolarHBondContact O-N 2.85Å; K464-N467 PolarHBondContact O-N 2.93Å; K464-V468 WeakPolarHBondContact O-CB 3.48Å; K464-V468 WeakPolarHBondContact O-CG2 3.37Å; K464-V468 PolarHBondContact O-N 3.49Å; K464-G486 PolarHBondContact NZ-O 2.87Å; K464-L487 HydrophobicContact CB-CD2 3.94Å; K464-S490 WeakPolarHBondContact CD-OG 3.39Å; K464-S490 VanDerWaalsContact CE-OG 3.27Å; K464-S490 WeakPolarHBondContact CE-OG 3.38Å; K464-S490 PolarHBondContact NZ-OG 3.34Å
465V93.2Very high85.3Confident3 Ų374.6 Ų74.62%0.01840%0.401CS..Hα-helixtrans-58.7-46.4177.8167.40000111.4I388 C391 R392 L461 H462 S469 L487I388-V465 HydrophobicContact CG2-CG1 4.35Å; C391-V465 HydrophobicContact CB-CG2 3.38Å; R392-V465 HydrophobicContact CG-CG1 3.45Å; R392-V465 VanDerWaalsContact CG-CG1 3.45Å; L461-V465 HydrophobicContact CD1-CG2 4.12Å; L461-V465 HydrophobicContact CG-CG2 4.39Å; L461-V465 VanDerWaalsContact O-CG2 3.3Å; L461-V465 WeakPolarHBondContact O-CG2 3.44Å; L461-V465 PolarHBondContact O-N 3.46Å; H462-V465 PolarHBondContact O-N 3.38Å; V465-S469 VanDerWaalsContact O-CB 3.3Å; V465-S469 WeakPolarHBondContact O-CB 2.84Å; V465-S469 PolarHBondContact O-N 3.48Å; V465-S469 PolarHBondContact O-OG 3.11Å; V465-L487 HydrophobicContact CG2-CD2 3.86Å
466E92.5Very high83.5Confident60 Ų6071 Ų7128%0.2840%0.397SS..Hα-helixtrans-71.2-37.7-178.9-67-54.312300112.4R392 H462 T463 K464 S469 Q470R392-E466 IonicContact CZ-OE1 2.79Å; R392-E466 IonicContact NE-OE1 2.61Å; R392-E466 PolarHBondContact NE-OE1 2.74Å; R392-E466 IonicContact NH2-OE1 3.3Å; R392-E466 PolarHBondContact NH2-OE1 2.97Å; R392-E466 IonicContact NH2-OE2 3.76Å; H462-E466 WeakPolarHBondContact O-CG 3.29Å; H462-E466 PolarHBondContact O-N 3.26Å; T463-E466 PolarHBondContact O-N 2.89Å; K464-E466 VanDerWaalsContact C-N 3.34Å; K464-E466 PolarHBondContact O-N 2.85Å; E466-S469 PolarHBondContact O-N 3.38Å; E466-Q470 VanDerWaalsContact O-CG 3.31Å; E466-Q470 WeakPolarHBondContact O-CG 3.3Å; E466-Q470 PolarHBondContact O-N 3.29Å
467N90.1Very high81.7Confident92 Ų9272.7 Ų72.749%0.49241%0.406SS..Hα-helixtrans-62.8-47.3174.3-71.2-12.6000111.8T463 K464 S469 Q470 C471T463-N467 WeakPolarHBondContact O-CB 3.21Å; T463-N467 PolarHBondContact O-N 3.5Å; T463-N467 PolarHBondContact O-ND2 2.98Å; K464-N467 PolarHBondContact O-N 2.93Å; N467-S469 VanDerWaalsContact C-N 3.29Å; N467-S469 PolarHBondContact O-N 3.42Å; N467-Q470 PolarHBondContact O-N 2.94Å; N467-C471 PolarHBondContact O-SG 2.86Å
468V87.5Confident80.3Confident17 Ų1775.6 Ų75.610%0.10342%0.423CS..Hα-helixtrans-66.9-33.2180176.20000111.1L384 I388 K464 Q470 C471 M483 L487L384-V468 HydrophobicContact CD1-CG1 3.81Å; L384-V468 HydrophobicContact CD2-CG1 3.57Å; L384-V468 HydrophobicContact CG-CG1 3.84Å; I388-V468 HydrophobicContact CD1-CG1 3.85Å; I388-V468 HydrophobicContact CG1-CG1 3.98Å; K464-V468 WeakPolarHBondContact O-CB 3.48Å; K464-V468 WeakPolarHBondContact O-CG2 3.37Å; K464-V468 PolarHBondContact O-N 3.49Å; V468-Q470 PolarHBondContact O-N 2.9Å; V468-C471 PolarHBondContact O-N 2.83Å; V468-M483 HydrophobicContact CG1-CB 4.48Å; V468-M483 HydrophobicContact CG1-SD 4.06Å; V468-M483 HydrophobicContact CG2-CB 4.35Å; V468-M483 HydrophobicContact CG2-CG 4.36Å; V468-M483 HydrophobicContact CG2-SD 4.34Å; V468-L487 HydrophobicContact CG1-CD1 4.21Å; V468-L487 HydrophobicContact CG2-CD1 4.49Å; V468-L487 HydrophobicContact CG2-CG 4.47Å
469S85.4Confident79.4Confident39 Ų3976.5 Ų76.527%0.27343%0.431SS..Hα-helixtrans-70.5-17176.5-60.70000114.2I388 R392 V465 E466 N467I388-S469 WeakPolarHBondContact CG2-OG 3.45Å; R392-S469 PolarHBondContact NH2-OG 2.82Å; R392-S469 VanDerWaalsContact NH2-OG 3.08Å; V465-S469 VanDerWaalsContact O-CB 3.3Å; V465-S469 WeakPolarHBondContact O-CB 2.84Å; V465-S469 PolarHBondContact O-N 3.48Å; V465-S469 PolarHBondContact O-OG 3.11Å; E466-S469 PolarHBondContact O-N 3.38Å; N467-S469 VanDerWaalsContact C-N 3.29Å; N467-S469 PolarHBondContact O-N 3.42Å
470Q83.3Confident78.8Confident140 Ų14076.8 Ų76.865%0.65442%0.423SS*.THydrogen-bonded Turntrans-97.4-4.9179.3-70174.316.400113E466 N467 V468 D472E466-Q470 VanDerWaalsContact O-CG 3.31Å; E466-Q470 WeakPolarHBondContact O-CG 3.3Å; E466-Q470 PolarHBondContact O-N 3.29Å; N467-Q470 PolarHBondContact O-N 2.94Å; V468-Q470 PolarHBondContact O-N 2.9Å; Q470-D472 PolarHBondContact O-N 2.7Å
471C74.5Confident78.1Confident62 Ų6276.9 Ų76.942%0.41943%0.426SS..  trans-78.298.7176.3-68.80000110.3N467 V468 E473 M483N467-C471 PolarHBondContact O-SG 2.86Å; V468-C471 PolarHBondContact O-N 2.83Å; C471-E473 VanDerWaalsContact C-N 3.32Å; C471-E473 PolarHBondContact O-N 3.03Å; C471-M483 HydrophobicContact CB-CE 4.47Å
472D61.5Low77.7Confident161 Ų16183.6 Ų83.686%0.86146%0.458SS*.SBendtrans-72.9-19.2178.5-77.9-32.4000113.8Q470Q470-D472 PolarHBondContact O-N 2.7Å
473E56.2Low77.4Confident160 Ų16080.9 Ų80.975%0.74845%0.446SS*.  trans-135.999.1-174.7-68.3-177.4162.400111.2C471 E475C471-E473 VanDerWaalsContact C-N 3.32Å; C471-E473 PolarHBondContact O-N 3.03Å; E473-E475 PolarHBondContact O-N 3.45Å
474V55.4Low77.1Confident53 Ų5379 Ų7932%0.32143%0.432SS..  trans-83.793169.4-171.50000108.4L384 G476 E480L384-V474 HydrophobicContact CD2-CG2 4.31Å; V474-G476 PolarHBondContact O-N 3.5Å; V474-E480 HydrophobicContact CG1-CB 3.83Å
475E49.5Very low76.9Confident174 Ų17481.3 Ų81.381%0.81345%0.447SS*.  trans-69.689.5173.9-70.4-168.2156.400110.7E473E473-E475 PolarHBondContact O-N 3.45Å
476G59.8Low76.7Confident48 Ų4882.3 Ų82.350%0.49546%0.457SS..SBendtrans96.5148.5167.700000116.1V474 N478 S479V474-G476 PolarHBondContact O-N 3.5Å; G476-N478 PolarHBondContact O-N 2.84Å; G476-N478 VanDerWaalsContact O-N 3.11Å; G476-S479 PolarHBondContact O-N 3.3Å; G476-S479 VanDerWaalsContact O-N 3.12Å
477S59.2Low76.7Confident94 Ų9479.5 Ų79.566%0.65744%0.444SS*.Hα-helixtrans-58.6-26.6-174.259.40000114.8A481S477-A481 PolarHBondContact O-N 2.89Å
478N67.1Low76.8Confident124 Ų12478.3 Ų78.366%0.66344%0.436SS*.Hα-helixtrans-72.3-35.6179.6-72-2.4000112.1G476 A481 E482G476-N478 PolarHBondContact O-N 2.84Å; G476-N478 VanDerWaalsContact O-N 3.11Å; N478-A481 PolarHBondContact O-N 3.06Å; N478-E482 WeakPolarHBondContact O-CG 3.31Å; N478-E482 PolarHBondContact O-N 2.84Å; N478-E482 VanDerWaalsContact O-N 3.14Å
479S79.4Confident77Confident41 Ų4183.7 Ų83.729%0.28746%0.459SS..Hα-helixtrans-68.6-41.1179.8-175.70000111.3G476 A481 E482 M483G476-S479 PolarHBondContact O-N 3.3Å; G476-S479 VanDerWaalsContact O-N 3.12Å; S479-A481 PolarHBondContact O-N 3.21Å; S479-E482 PolarHBondContact O-N 3.1Å; S479-M483 WeakPolarHBondContact O-CG 3.2Å; S479-M483 PolarHBondContact O-N 3.06Å
480E82.5Confident77.4Confident62 Ų6281.9 Ų81.929%0.2945%0.447SS..Hα-helixtrans-60.8-46.8175.8-162.1178.9175.300111.8G383 L384 V474 E482 M483 I484G383-E480 WeakPolarHBondContact CA-OE1 3.32Å; L384-E480 HydrophobicContact CB-CG 4.02Å; L384-E480 PolarHBondContact N-OE1 3.24Å; V474-E480 HydrophobicContact CG1-CB 3.83Å; E480-E482 VanDerWaalsContact C-N 3.33Å; E480-E482 PolarHBondContact O-N 2.69Å; E480-M483 PolarHBondContact O-N 2.76Å; E480-I484 HydrophobicContact CG-CD1 4.14Å; E480-I484 WeakPolarHBondContact O-CG1 3.47Å; E480-I484 PolarHBondContact O-N 2.98Å
481A83.8Confident77.9Confident46 Ų4675.2 Ų75.238%0.3842%0.416SS..Hα-helixtrans-60.6-41.8179.300000112.1S477 N478 S479 I484 I485S477-A481 PolarHBondContact O-N 2.89Å; N478-A481 PolarHBondContact O-N 3.06Å; S479-A481 PolarHBondContact O-N 3.21Å; A481-I484 PolarHBondContact O-N 3.33Å; A481-I485 WeakPolarHBondContact O-CD1 3.49Å; A481-I485 VanDerWaalsContact O-CG1 3.23Å; A481-I485 WeakPolarHBondContact O-CG1 3.41Å; A481-I485 PolarHBondContact O-N 2.83Å
482E87.3Confident78.7Confident141 Ų14174 Ų7466%0.65940%0.404SS*.Hα-helixtrans-64-40.7175.5-73.9177.1-174.900112.3N478 S479 E480 I485 G486N478-E482 WeakPolarHBondContact O-CG 3.31Å; N478-E482 PolarHBondContact O-N 2.84Å; N478-E482 VanDerWaalsContact O-N 3.14Å; S479-E482 PolarHBondContact O-N 3.1Å; E480-E482 VanDerWaalsContact C-N 3.33Å; E480-E482 PolarHBondContact O-N 2.69Å; E482-I485 PolarHBondContact O-N 3.26Å; E482-G486 PolarHBondContact O-N 2.99Å
483M88.1Confident80.3Confident40 Ų4067.1 Ų67.120%0.19737%0.369CS..Hα-helixtrans-62.7-44.6174.7-69.2-177.1-168.100111.7L384 V468 C471 S479 E480 G486 L487L384-M483 HydrophobicContact CD1-CB 3.93Å; L384-M483 HydrophobicContact CD2-SD 4.06Å; V468-M483 HydrophobicContact CG1-CB 4.48Å; V468-M483 HydrophobicContact CG1-SD 4.06Å; V468-M483 HydrophobicContact CG2-CB 4.35Å; V468-M483 HydrophobicContact CG2-CG 4.36Å; V468-M483 HydrophobicContact CG2-SD 4.34Å; C471-M483 HydrophobicContact CB-CE 4.47Å; S479-M483 WeakPolarHBondContact O-CG 3.2Å; S479-M483 PolarHBondContact O-N 3.06Å; E480-M483 PolarHBondContact O-N 2.76Å; M483-G486 PolarHBondContact O-N 3.43Å; M483-L487 WeakPolarHBondContact O-CG 3.23Å; M483-L487 PolarHBondContact O-N 3.23Å
484I88.7Confident82.2Confident35 Ų3559.5 Ų59.518%0.17933%0.333CS..Hα-helixtrans-61.2-47.8176.8-67.4170.1000110.3F379 L384 E480 A481 G486 L487 H488F379-I484 HydrophobicContact CD1-CG2 3.7Å; F379-I484 HydrophobicContact CE1-CG2 4.02Å; F379-I484 WeakPolarHBondContact CE1-O 3.32Å; L384-I484 HydrophobicContact CD1-CG1 3.64Å; E480-I484 HydrophobicContact CG-CD1 4.14Å; E480-I484 WeakPolarHBondContact O-CG1 3.47Å; E480-I484 PolarHBondContact O-N 2.98Å; A481-I484 PolarHBondContact O-N 3.33Å; I484-G486 VanDerWaalsContact C-N 3.29Å; I484-G486 PolarHBondContact O-N 3.4Å; I484-L487 PolarHBondContact O-N 3.25Å; I484-H488 WeakPolarHBondContact O-CB 3.46Å; I484-H488 PolarHBondContact O-N 3.49Å
485I89Confident84.1Confident116 Ų11657 Ų5760%0.59532%0.318SS*.Hα-helixtrans-59.5-42.2176.7-68.5164.2000110.9A481 E482 H488 H489A481-I485 WeakPolarHBondContact O-CD1 3.49Å; A481-I485 VanDerWaalsContact O-CG1 3.23Å; A481-I485 WeakPolarHBondContact O-CG1 3.41Å; A481-I485 PolarHBondContact O-N 2.83Å; E482-I485 PolarHBondContact O-N 3.26Å; I485-H488 PolarHBondContact O-N 3.47Å; I485-H489 WeakPolarHBondContact O-CB 3.29Å; I485-H489 PolarHBondContact O-N 2.85Å
486G90.2Very high86.2Confident23 Ų2349.8 Ų49.824%0.23729%0.285CS..Hα-helixtrans-64.7-40.2179.200000113.7K464 E482 M483 I484 S490K464-G486 PolarHBondContact NZ-O 2.87Å; E482-G486 PolarHBondContact O-N 2.99Å; M483-G486 PolarHBondContact O-N 3.43Å; I484-G486 VanDerWaalsContact C-N 3.29Å; I484-G486 PolarHBondContact O-N 3.4Å; G486-S490 PolarHBondContact O-N 3.24Å
487L92.1Very high88Confident1 Ų149.3 Ų49.31%0.00527%0.268CS..Hα-helixtrans-67.1-45.3172.7-74.8174.8000111F379 L384 I388 K464 V465 V468 M483 I484 H489 S490 A491F379-L487 HydrophobicContact CE1-CB 4.16Å; F379-L487 HydrophobicContact CZ-CB 4.15Å; L384-L487 HydrophobicContact CD1-CD1 4.3Å; I388-L487 HydrophobicContact CG1-CD1 4.26Å; K464-L487 HydrophobicContact CB-CD2 3.94Å; V465-L487 HydrophobicContact CG2-CD2 3.86Å; V468-L487 HydrophobicContact CG1-CD1 4.21Å; V468-L487 HydrophobicContact CG2-CD1 4.49Å; V468-L487 HydrophobicContact CG2-CG 4.47Å; M483-L487 WeakPolarHBondContact O-CG 3.23Å; M483-L487 PolarHBondContact O-N 3.23Å; I484-L487 PolarHBondContact O-N 3.25Å; L487-H489 VanDerWaalsContact C-N 3.33Å; L487-H489 PolarHBondContact O-N 2.81Å; L487-S490 PolarHBondContact O-N 3.2Å; L487-A491 VanDerWaalsContact O-CB 3.29Å; L487-A491 WeakPolarHBondContact O-CB 3.43Å; L487-A491 PolarHBondContact O-N 3.33Å
488H91.7Very high89.7Confident67 Ų6744.8 Ų44.831%0.3124%0.237SC..Hα-helixtrans-56.1-49.2178.2179.9-83.1000110.7F375 F379 I484 I485 S490 A491 E492F375-H488 AromaticContact CE1-CD2 3.45Å; F375-H488 VanDerWaalsContact CE1-CD2 3.45Å; F375-H488 WeakPolarHBondContact CE1-CD2 3.22Å; F375-H488 AromaticContact CE1-NE2 3.39Å; F375-H488 WeakPolarHBondContact CE1-NE2 3.33Å; F375-H488 HydrophobicContact CZ-CB 4.21Å; F375-H488 AromaticContact CZ-CD2 3.26Å; F375-H488 WeakPolarHBondContact CZ-CD2 3.04Å; F375-H488 AromaticContact CZ-CG 3.7Å; F375-H488 AromaticContact CZ-NE2 3.71Å; F375-H488 WeakPolarHBondContact CZ-O 3.07Å; F379-H488 HydrophobicContact CD1-CB 3.68Å; F379-H488 AromaticContact CD1-CD2 3.82Å; F379-H488 HydrophobicContact CE1-CB 3.51Å; F379-H488 AromaticContact CG-CD2 3.88Å; F379-H488 HydrophobicContact CZ-CB 4.25Å; I484-H488 WeakPolarHBondContact O-CB 3.46Å; I484-H488 PolarHBondContact O-N 3.49Å; I485-H488 PolarHBondContact O-N 3.47Å; H488-S490 PolarHBondContact O-N 3.24Å; H488-A491 PolarHBondContact O-N 2.91Å; H488-E492 VanDerWaalsContact O-CB 3.27Å; H488-E492 WeakPolarHBondContact O-CB 3.32Å; H488-E492 PolarHBondContact O-N 3.06Å
489H92.1Very high91.1Very high130 Ų13040.7 Ų40.760%0.60221%0.214SC*.Hα-helixtrans-62.1-43.2-179.3-173.372.3000113.1I485 L487 E492 A493I485-H489 WeakPolarHBondContact O-CB 3.29Å; I485-H489 PolarHBondContact O-N 2.85Å; L487-H489 VanDerWaalsContact C-N 3.33Å; L487-H489 PolarHBondContact O-N 2.81Å; H489-E492 PolarHBondContact O-N 3.44Å; H489-A493 WeakPolarHBondContact O-CB 3.35Å; H489-A493 PolarHBondContact O-N 2.78Å
490S93Very high91.9Very high2 Ų238.8 Ų38.81%0.01420%0.2CC..Hα-helixtrans-70.1-36.3177.7-83.30000113S460 K464 G486 L487 H488 A493 V494S460-S490 PolarHBondContact OG-OG 3.14Å; K464-S490 WeakPolarHBondContact CD-OG 3.39Å; K464-S490 VanDerWaalsContact CE-OG 3.27Å; K464-S490 WeakPolarHBondContact CE-OG 3.38Å; K464-S490 PolarHBondContact NZ-OG 3.34Å; G486-S490 PolarHBondContact O-N 3.24Å; L487-S490 PolarHBondContact O-N 3.2Å; H488-S490 PolarHBondContact O-N 3.24Å; S490-A493 PolarHBondContact O-N 3.03Å; S490-V494 WeakPolarHBondContact O-CG2 3.38Å; S490-V494 PolarHBondContact O-N 3.44Å
491A93.5Very high92.6Very high0 Ų036 Ų360%019%0.187CC..Hα-helixtrans-65.7-4417500000111.4F375 L394 L461 L487 H488 A493 V494 L495F375-A491 HydrophobicContact CD2-CB 3.96Å; F375-A491 HydrophobicContact CE2-CB 3.18Å; F375-A491 HydrophobicContact CZ-CB 3.74Å; L394-A491 HydrophobicContact CD2-CB 3.47Å; L394-A491 VanDerWaalsContact CD2-CB 3.47Å; L461-A491 HydrophobicContact CD1-CB 4.13Å; L461-A491 HydrophobicContact CD2-CB 4.46Å; L487-A491 VanDerWaalsContact O-CB 3.29Å; L487-A491 WeakPolarHBondContact O-CB 3.43Å; L487-A491 PolarHBondContact O-N 3.33Å; H488-A491 PolarHBondContact O-N 2.91Å; A491-A493 VanDerWaalsContact C-N 3.33Å; A491-A493 PolarHBondContact O-N 3.38Å; A491-V494 PolarHBondContact O-N 2.81Å; A491-L495 WeakPolarHBondContact O-CG 3.26Å; A491-L495 PolarHBondContact O-N 3Å
492E93Very high93.2Very high37 Ų3734.2 Ų34.217%0.17317%0.171CC..Hα-helixtrans-60.9-41.4174.9-176.166.7178.800111.7R372 H488 H489 V494 L495 I496R372-E492 IonicContact CZ-OE1 3.57Å; R372-E492 IonicContact NE-OE1 3.75Å; R372-E492 IonicContact NE-OE2 2.9Å; R372-E492 IonicContact NH2-OE1 2.68Å; R372-E492 PolarHBondContact NH2-OE1 3.32Å; R372-E492 IonicContact NH2-OE2 2.8Å; H488-E492 VanDerWaalsContact O-CB 3.27Å; H488-E492 WeakPolarHBondContact O-CB 3.32Å; H488-E492 PolarHBondContact O-N 3.06Å; H489-E492 PolarHBondContact O-N 3.44Å; E492-V494 PolarHBondContact O-N 3.49Å; E492-L495 PolarHBondContact O-N 3.27Å; E492-I496 HydrophobicContact CG-CD1 3.97Å; E492-I496 VanDerWaalsContact O-CG1 3.31Å; E492-I496 WeakPolarHBondContact O-CG1 3.22Å; E492-I496 PolarHBondContact O-N 2.68Å
493A94.4Very high93.6Very high15 Ų1529.6 Ų29.612%0.12415%0.151CC..Hα-helixtrans-59.2-44.8175.800000112.1E457 H489 S490 A491 L495 I496 R497E457-A493 HydrophobicContact CG-CB 4.15Å; E457-A493 WeakPolarHBondContact OE2-CB 3.4Å; H489-A493 WeakPolarHBondContact O-CB 3.35Å; H489-A493 PolarHBondContact O-N 2.78Å; S490-A493 PolarHBondContact O-N 3.03Å; A491-A493 VanDerWaalsContact C-N 3.33Å; A491-A493 PolarHBondContact O-N 3.38Å; A493-L495 PolarHBondContact O-N 3.26Å; A493-I496 PolarHBondContact O-N 3.3Å; A493-R497 WeakPolarHBondContact O-CG 3.44Å; A493-R497 PolarHBondContact O-N 2.98Å
494V95.8Very high93.9Very high0 Ų027.7 Ų27.70%014%0.141CC..Hα-helixtrans-60.4-44175.4172.70000111.5A398 F454 E457 L458 L461 S490 A491 E492 R497 L498A398-V494 HydrophobicContact CB-CG1 3.87Å; F454-V494 HydrophobicContact CE2-CG1 3.99Å; E457-V494 HydrophobicContact CB-CG2 3.92Å; L458-V494 HydrophobicContact CD1-CG1 4.27Å; L461-V494 HydrophobicContact CB-CG2 4.15Å; L461-V494 HydrophobicContact CD2-CG2 4.01Å; S490-V494 WeakPolarHBondContact O-CG2 3.38Å; S490-V494 PolarHBondContact O-N 3.44Å; A491-V494 PolarHBondContact O-N 2.81Å; E492-V494 PolarHBondContact O-N 3.49Å; V494-R497 PolarHBondContact O-N 2.7Å; V494-L498 HydrophobicContact CG1-CD1 4.46Å; V494-L498 PolarHBondContact O-N 3.47Å; V494-L498 VanDerWaalsContact O-N 3.1Å
495L94.8Very high94.3Very high0 Ų026.1 Ų26.10%013%0.133CC..Hα-helixtrans-61.9-46.2176.9-69.2176.4000111.6L371 R372 F375 L394 A491 E492 A493 R497 L498 E499L371-L495 HydrophobicContact CD2-CD2 3.55Å; L371-L495 HydrophobicContact CG-CD2 3.82Å; R372-L495 HydrophobicContact CB-CD1 4.46Å; R372-L495 HydrophobicContact CG-CD1 4.32Å; F375-L495 HydrophobicContact CB-CD1 4.44Å; F375-L495 HydrophobicContact CD1-CD1 4.25Å; F375-L495 HydrophobicContact CG-CD1 4.31Å; L394-L495 HydrophobicContact CD1-CD2 3.75Å; L394-L495 HydrophobicContact CD1-CG 4.34Å; A491-L495 WeakPolarHBondContact O-CG 3.26Å; A491-L495 PolarHBondContact O-N 3Å; E492-L495 PolarHBondContact O-N 3.27Å; A493-L495 PolarHBondContact O-N 3.26Å; L495-R497 VanDerWaalsContact C-N 3.28Å; L495-R497 PolarHBondContact O-N 3.31Å; L495-L498 PolarHBondContact O-N 3.26Å; L495-E499 WeakPolarHBondContact O-CG 3.37Å; L495-E499 PolarHBondContact O-N 3.44Å
496I95.3Very high94.6Very high23 Ų2320.7 Ų20.712%0.11811%0.105CC..Hα-helixtrans-58.6-40.1176.7-71168.6000111.1G441 V442 E492 A493 E499 S500G441-I496 VanDerWaalsContact C-CG2 3.42Å; G441-I496 WeakPolarHBondContact O-CG2 3.32Å; V442-I496 HydrophobicContact CG2-CG2 4.44Å; E492-I496 HydrophobicContact CG-CD1 3.97Å; E492-I496 VanDerWaalsContact O-CG1 3.31Å; E492-I496 WeakPolarHBondContact O-CG1 3.22Å; E492-I496 PolarHBondContact O-N 2.68Å; A493-I496 PolarHBondContact O-N 3.3Å; I496-E499 PolarHBondContact O-N 3.1Å; I496-S500 VanDerWaalsContact O-CB 3.22Å; I496-S500 WeakPolarHBondContact O-CB 3.49Å; I496-S500 PolarHBondContact O-N 3.28Å; I496-S500 PolarHBondContact O-OG 3.01Å
497R96.3Very high94.9Very high38 Ų3819.9 Ų19.914%0.14310%0.096CC..Hα-helixtrans-64.3-43.3176.8-67.9-50.8103.6172.15.7112.1G441 D453 F454 E457 A493 V494 L495 S500 L501G441-R497 PolarHBondContact O-NH2 2.88Å; D453-R497 HydrophobicContact CB-CG 4.36Å; D453-R497 IonicContact OD2-NH1 3.65Å; D453-R497 PolarHBondContact OD2-NH1 3.47Å; F454-R497 HydrophobicContact CB-CB 4.39Å; F454-R497 HydrophobicContact CD2-CB 4.29Å; E457-R497 HydrophobicContact CB-CG 4.36Å; E457-R497 HydrophobicContact CG-CG 3.95Å; A493-R497 WeakPolarHBondContact O-CG 3.44Å; A493-R497 PolarHBondContact O-N 2.98Å; V494-R497 PolarHBondContact O-N 2.7Å; L495-R497 VanDerWaalsContact C-N 3.28Å; L495-R497 PolarHBondContact O-N 3.31Å; R497-S500 WeakPolarHBondContact O-CB 3.39Å; R497-S500 PolarHBondContact O-N 3.4Å; R497-L501 WeakPolarHBondContact O-CB 3.04Å; R497-L501 PolarHBondContact O-N 3.37Å
498L96.3Very high95Very high0 Ų019.9 Ų19.90%010%0.095CC..Hα-helixtrans-63.8-43.7176.3-70.6170.6000112.3L368 A398 L401 H402 I405 F454 V494 L495 S500 L501 H502L368-L498 HydrophobicContact CD2-CB 3.68Å; L368-L498 HydrophobicContact CD2-CD1 4.24Å; A398-L498 HydrophobicContact CB-CD1 3.84Å; L401-L498 HydrophobicContact CD2-CD1 4.47Å; H402-L498 HydrophobicContact CB-CD2 3.79Å; I405-L498 HydrophobicContact CD1-CD2 4.34Å; F454-L498 HydrophobicContact CD2-CD2 3.97Å; F454-L498 HydrophobicContact CD2-CG 4.14Å; F454-L498 HydrophobicContact CE2-CD1 4.27Å; F454-L498 HydrophobicContact CE2-CD2 3.51Å; F454-L498 HydrophobicContact CE2-CG 3.75Å; F454-L498 HydrophobicContact CZ-CD2 4.15Å; V494-L498 HydrophobicContact CG1-CD1 4.46Å; V494-L498 PolarHBondContact O-N 3.47Å; V494-L498 VanDerWaalsContact O-N 3.1Å; L495-L498 PolarHBondContact O-N 3.26Å; L498-S500 VanDerWaalsContact C-N 3.35Å; L498-L501 PolarHBondContact O-N 3.39Å; L498-H502 WeakPolarHBondContact O-CB 3.33Å; L498-H502 PolarHBondContact O-N 3.34Å
499E95.6Very high95.2Very high38 Ų3817 Ų1718%0.1788%0.082CC..Hα-helixtrans-61.3-43.6175.3-72.5176.8178.700111.1L368 R372 V442 L495 I496 H502 L503L368-E499 HydrophobicContact CD1-CG 4.2Å; R372-E499 IonicContact CZ-OE1 2.84Å; R372-E499 IonicContact NH1-OE1 3.79Å; R372-E499 PolarHBondContact NH1-OE1 2.87Å; R372-E499 IonicContact NH1-OE2 2.81Å; R372-E499 PolarHBondContact NH1-OE2 3.13Å; V442-E499 HydrophobicContact CG2-CB 4.11Å; L495-E499 WeakPolarHBondContact O-CG 3.37Å; L495-E499 PolarHBondContact O-N 3.44Å; I496-E499 PolarHBondContact O-N 3.1Å; E499-H502 PolarHBondContact O-N 3Å; E499-L503 VanDerWaalsContact O-CB 3.26Å; E499-L503 WeakPolarHBondContact O-CB 3.38Å; E499-L503 PolarHBondContact O-N 3.34Å
500S95.8Very high95.4Very high0 Ų010.9 Ų10.90%05%0.054CC..Hα-helixtrans-61.2-45.9176.9-62.80000112.4V442 R443 H450 I496 R497 L498 T504V442-S500 WeakPolarHBondContact CA-OG 3.26Å; R443-S500 PolarHBondContact N-OG 2.89Å; R443-S500 VanDerWaalsContact N-OG 3.1Å; R443-S500 VanDerWaalsContact O-CB 3.27Å; R443-S500 WeakPolarHBondContact O-CB 3.34Å; H450-S500 PolarHBondContact CE1-O 3.13Å; I496-S500 VanDerWaalsContact O-CB 3.22Å; I496-S500 WeakPolarHBondContact O-CB 3.49Å; I496-S500 PolarHBondContact O-N 3.28Å; I496-S500 PolarHBondContact O-OG 3.01Å; R497-S500 WeakPolarHBondContact O-CB 3.39Å; R497-S500 PolarHBondContact O-N 3.4Å; L498-S500 VanDerWaalsContact C-N 3.35Å; S500-T504 VanDerWaalsContact O-CB 3.32Å; S500-T504 WeakPolarHBondContact O-CB 3.27Å; S500-T504 PolarHBondContact O-N 3.34Å; S500-T504 PolarHBondContact O-OG1 3.34Å
501L97Very high95.5Very high3 Ų310.8 Ų10.82%0.0165%0.053CC..Hα-helixtrans-62.9-49.2176.1173.363.4000110.8H402 I405 L406 L447 H450 R497 L498 L503 T504 L505H402-L501 WeakPolarHBondContact CD2-CD2 3.38Å; I405-L501 HydrophobicContact CB-CD2 4.35Å; I405-L501 HydrophobicContact CG2-CD2 3.8Å; I405-L501 HydrophobicContact CG2-CG 3.79Å; L406-L501 HydrophobicContact CD2-CD1 4.15Å; L406-L501 HydrophobicContact CD2-CD2 4.16Å; L406-L501 HydrophobicContact CG-CD2 4.36Å; L447-L501 HydrophobicContact CD1-CD1 3.84Å; H450-L501 HydrophobicContact CB-CB 4.37Å; H450-L501 HydrophobicContact CB-CD1 3.84Å; H450-L501 PolarHBondContact CE1-N 3.07Å; R497-L501 WeakPolarHBondContact O-CB 3.04Å; R497-L501 PolarHBondContact O-N 3.37Å; L498-L501 PolarHBondContact O-N 3.39Å; L501-L503 PolarHBondContact O-N 3.2Å; L501-T504 PolarHBondContact O-N 3.11Å; L501-L505 HydrophobicContact CD1-CD1 3.84Å; L501-L505 HydrophobicContact CD1-CG 4.12Å; L501-L505 HydrophobicContact CG-CD1 4.13Å; L501-L505 WeakPolarHBondContact O-CG 3.36Å; L501-L505 PolarHBondContact O-N 3.31Å
502H96.4Very high95.5Very high9 Ų910.9 Ų10.94%0.0425%0.054CC..Hα-helixtrans-57.9-50.2179.5177.663.4000111.4M361 L368 I405 L498 E499 T504 L505 V506M361-H502 PolarHBondContact O-CE1 2.69Å; M361-H502 VanDerWaalsContact O-CE1 3.25Å; L368-H502 HydrophobicContact CD1-CB 4.02Å; I405-H502 HydrophobicContact CD1-CB 4.28Å; L498-H502 WeakPolarHBondContact O-CB 3.33Å; L498-H502 PolarHBondContact O-N 3.34Å; E499-H502 PolarHBondContact O-N 3Å; H502-T504 PolarHBondContact O-N 3.36Å; H502-L505 PolarHBondContact O-N 2.91Å; H502-V506 WeakPolarHBondContact O-CG2 3.46Å; H502-V506 PolarHBondContact O-N 3.31Å
503L95.5Very high95.6Very high45 Ų459.1 Ų9.124%0.2365%0.046CC..Hα-helixtrans-59.7-46.1178.9-177.366.9000111.8V442 E499 L501 L505 V506 H507V442-L503 HydrophobicContact CG1-CD2 3.64Å; E499-L503 VanDerWaalsContact O-CB 3.26Å; E499-L503 WeakPolarHBondContact O-CB 3.38Å; E499-L503 PolarHBondContact O-N 3.34Å; L501-L503 PolarHBondContact O-N 3.2Å; L503-L505 VanDerWaalsContact C-N 3.29Å; L503-L505 PolarHBondContact O-N 2.8Å; L503-V506 PolarHBondContact O-N 2.95Å; L503-H507 VanDerWaalsContact CD1-CE1 3.5Å; L503-H507 WeakPolarHBondContact CD1-CE1 3.35Å; L503-H507 WeakPolarHBondContact CD1-NE2 3.32Å; L503-H507 VanDerWaalsContact O-CG 3.3Å; L503-H507 PolarHBondContact O-N 3.02Å
504T95.9Very high95.7Very high0 Ų08.4 Ų8.40%04%0.04CC..Hα-helixtrans-56.1-46177.5-64.10000111.1T420 V444 Q445 H450 S500 L501 H502 H507 C508T420-T504 HydrophobicContact CG2-CG2 4.06Å; V444-T504 HydrophobicContact CG1-CG2 4.16Å; Q445-T504 WeakPolarHBondContact O-CG2 3.3Å; H450-T504 PolarHBondContact CE1-OG1 3.49Å; H450-T504 WeakPolarHBondContact NE2-CB 3.33Å; H450-T504 PolarHBondContact NE2-OG1 3.46Å; S500-T504 VanDerWaalsContact O-CB 3.32Å; S500-T504 WeakPolarHBondContact O-CB 3.27Å; S500-T504 PolarHBondContact O-N 3.34Å; S500-T504 PolarHBondContact O-OG1 3.34Å; L501-T504 PolarHBondContact O-N 3.11Å; H502-T504 PolarHBondContact O-N 3.36Å; T504-H507 PolarHBondContact O-N 3.03Å; T504-C508 PolarHBondContact O-N 2.81Å; T504-C508 PolarHBondContact O-SG 3.42Å
505L95.9Very high95.6Very high1 Ų110.9 Ų10.91%0.0055%0.053CC..Hα-helixtrans-71.3-33.5-179.2-68.3175.9000112.9I405 F409 L416 L447 L501 H502 L503 H507 C508 Y509I405-L505 HydrophobicContact CG2-CD1 3.37Å; F409-L505 HydrophobicContact CD2-CB 4.11Å; F409-L505 HydrophobicContact CD2-CD1 3.92Å; F409-L505 HydrophobicContact CD2-CD2 4.31Å; F409-L505 HydrophobicContact CD2-CG 4.36Å; F409-L505 HydrophobicContact CE2-CB 3.54Å; F409-L505 HydrophobicContact CE2-CD1 4.11Å; F409-L505 HydrophobicContact CE2-CG 4.28Å; F409-L505 HydrophobicContact CG-CD2 4.41Å; F409-L505 HydrophobicContact CZ-CB 3.78Å; F409-L505 VanDerWaalsContact CZ-O 3.22Å; F409-L505 WeakPolarHBondContact CZ-O 3.45Å; L416-L505 HydrophobicContact CD1-CD2 3.84Å; L416-L505 HydrophobicContact CD2-CD2 3.95Å; L416-L505 HydrophobicContact CG-CD2 4.2Å; L447-L505 HydrophobicContact CD1-CD2 4.39Å; L501-L505 HydrophobicContact CD1-CD1 3.84Å; L501-L505 HydrophobicContact CD1-CG 4.12Å; L501-L505 HydrophobicContact CG-CD1 4.13Å; L501-L505 WeakPolarHBondContact O-CG 3.36Å; L501-L505 PolarHBondContact O-N 3.31Å; H502-L505 PolarHBondContact O-N 2.91Å; L503-L505 VanDerWaalsContact C-N 3.29Å; L503-L505 PolarHBondContact O-N 2.8Å; L505-H507 VanDerWaalsContact C-N 3.34Å; L505-C508 WeakPolarHBondContact O-CB 3.39Å; L505-C508 PolarHBondContact O-N 3.47Å; L505-Y509 PolarHBondContact O-N 3.44Å
506V95.7Very high95.6Very high2 Ų211.1 Ų11.11%0.0126%0.055CC..Hα-helixtrans-61.4-45169.7171.70000110.1F231 H235 M361 H502 L503 Y509 I510F231-V506 HydrophobicContact CE1-CG1 4.35Å; F231-V506 HydrophobicContact CZ-CG1 4.29Å; F231-V506 HydrophobicContact CZ-CG2 4.08Å; H235-V506 HydrophobicContact CB-CG1 3.91Å; M361-V506 HydrophobicContact CB-CG2 4.32Å; M361-V506 HydrophobicContact CG-CG2 4.15Å; M361-V506 HydrophobicContact SD-CG2 4.03Å; H502-V506 WeakPolarHBondContact O-CG2 3.46Å; H502-V506 PolarHBondContact O-N 3.31Å; L503-V506 PolarHBondContact O-N 2.95Å; V506-Y509 WeakPolarHBondContact O-CB 3.4Å; V506-Y509 PolarHBondContact O-N 3.03Å; V506-I510 HydrophobicContact CG1-CD1 4.07Å; V506-I510 WeakPolarHBondContact O-CG1 3.29Å; V506-I510 PolarHBondContact O-N 2.97Å
507H96Very high95.6Very high7 Ų710 Ų103%0.0325%0.049CC..Hα-helixtrans-65-38.9175.9-64.6165.3000112.7L239 Y241 L423 L503 T504 L505 Y509 I510 V511L239-H507 HydrophobicContact CD1-CB 4.26Å; Y241-H507 AromaticContact CE1-CE1 3.93Å; Y241-H507 AromaticContact CE1-ND1 3.82Å; Y241-H507 AromaticContact CZ-ND1 3.64Å; Y241-H507 WeakPolarHBondContact OH-CB 3.43Å; Y241-H507 VanDerWaalsContact OH-CG 3.32Å; Y241-H507 PolarHBondContact OH-ND1 3.44Å; L423-H507 HydrophobicContact CD1-CB 4.29Å; L423-H507 HydrophobicContact CD2-CB 4.49Å; L503-H507 VanDerWaalsContact CD1-CE1 3.5Å; L503-H507 WeakPolarHBondContact CD1-CE1 3.35Å; L503-H507 WeakPolarHBondContact CD1-NE2 3.32Å; L503-H507 VanDerWaalsContact O-CG 3.3Å; L503-H507 PolarHBondContact O-N 3.02Å; T504-H507 PolarHBondContact O-N 3.03Å; L505-H507 VanDerWaalsContact C-N 3.34Å; H507-Y509 VanDerWaalsContact C-N 3.29Å; H507-Y509 PolarHBondContact O-N 3.14Å; H507-I510 PolarHBondContact O-N 2.86Å; H507-V511 WeakPolarHBondContact O-CG2 3.33Å; H507-V511 PolarHBondContact O-N 3.5Å
508C95.2Very high95.3Very high0 Ų09.9 Ų9.90%06%0.056CC..Hα-helixtrans-55.7-45.8169.8-720000111.5L416 L419 T420 L423 T504 L505 V511 G512L416-C508 HydrophobicContact CD1-CB 4.05Å; L419-C508 HydrophobicContact CD2-CB 3.85Å; L419-C508 VanDerWaalsContact CD2-O 3.28Å; L419-C508 WeakPolarHBondContact CD2-O 3.17Å; L419-C508 HydrophobicContact CG-CB 4.41Å; T420-C508 WeakPolarHBondContact CG2-SG 3.26Å; L423-C508 HydrophobicContact CD1-CB 4.15Å; L423-C508 WeakPolarHBondContact CD1-SG 3.43Å; T504-C508 PolarHBondContact O-N 2.81Å; T504-C508 PolarHBondContact O-SG 3.42Å; L505-C508 WeakPolarHBondContact O-CB 3.39Å; L505-C508 PolarHBondContact O-N 3.47Å; C508-V511 PolarHBondContact O-N 3.16Å; C508-G512 PolarHBondContact O-N 3.27Å
509Y95.5Very high95.1Very high7 Ų713.2 Ų13.23%0.0278%0.077CC..Hα-helixtrans-63.3-44.7179.4-173.8-106000112C346 F347 V354 K357 L358 M361 F409 L505 V506 H507 G512 M513C346-Y509 VanDerWaalsContact O-CD2 3.26Å; C346-Y509 WeakPolarHBondContact O-CD2 3.37Å; C346-Y509 WeakPolarHBondContact O-CE2 3.22Å; F347-Y509 HydrophobicContact CB-CE2 4.31Å; F347-Y509 HydrophobicContact CD2-CE1 4.07Å; F347-Y509 AromaticContact CD2-CE2 3.78Å; F347-Y509 HydrophobicContact CD2-CE2 3.78Å; F347-Y509 AromaticContact CD2-CZ 3.51Å; F347-Y509 WeakPolarHBondContact CD2-OH 3.48Å; F347-Y509 HydrophobicContact CE2-CE1 4.43Å; F347-Y509 HydrophobicContact CG-CE2 4.49Å; V354-Y509 WeakPolarHBondContact CA-OH 3.31Å; V354-Y509 WeakPolarHBondContact CG1-OH 3.5Å; V354-Y509 WeakPolarHBondContact CG2-OH 3.39Å; K357-Y509 HydrophobicContact CB-CE2 4.4Å; K357-Y509 HydrophobicContact CG-CD2 4.01Å; K357-Y509 HydrophobicContact CG-CE1 4.32Å; K357-Y509 HydrophobicContact CG-CE2 3.59Å; L358-Y509 HydrophobicContact CD2-CD1 4.31Å; L358-Y509 HydrophobicContact CD2-CE1 3.96Å; M361-Y509 HydrophobicContact CE-CD1 4.1Å; M361-Y509 HydrophobicContact CE-CD2 4.27Å; M361-Y509 HydrophobicContact CE-CG 3.76Å; M361-Y509 HydrophobicContact SD-CD1 4.37Å; F409-Y509 HydrophobicContact CE1-CD2 4.41Å; L505-Y509 PolarHBondContact O-N 3.44Å; V506-Y509 WeakPolarHBondContact O-CB 3.4Å; V506-Y509 PolarHBondContact O-N 3.03Å; H507-Y509 VanDerWaalsContact C-N 3.29Å; H507-Y509 PolarHBondContact O-N 3.14Å; Y509-G512 PolarHBondContact O-N 2.87Å; Y509-M513 PolarHBondContact O-N 2.98Å
510I95.9Very high94.9Very high1 Ų114.9 Ų14.91%0.00510%0.096CC..Hα-helixtrans-61.2-49.6176.1-70168.8000110.7L232 H235 M236 L239 V506 H507 G512 M513 L514L232-I510 HydrophobicContact CD1-CD1 4.4Å; L232-I510 HydrophobicContact CD1-CG1 3.88Å; H235-I510 HydrophobicContact CB-CD1 3.64Å; M236-I510 HydrophobicContact CG-CD1 3.96Å; M236-I510 HydrophobicContact CG-CG1 4.14Å; M236-I510 HydrophobicContact CG-CG2 3.72Å; M236-I510 HydrophobicContact SD-CG2 4.46Å; L239-I510 HydrophobicContact CD2-CB 4.29Å; L239-I510 HydrophobicContact CD2-CG2 3.69Å; V506-I510 HydrophobicContact CG1-CD1 4.07Å; V506-I510 WeakPolarHBondContact O-CG1 3.29Å; V506-I510 PolarHBondContact O-N 2.97Å; H507-I510 PolarHBondContact O-N 2.86Å; I510-G512 VanDerWaalsContact C-N 3.29Å; I510-G512 PolarHBondContact O-N 3.07Å; I510-M513 CarbonylContact O-C 3.53Å; I510-M513 WeakPolarHBondContact O-CA 3.5Å; I510-M513 VanDerWaalsContact O-CB 3.27Å; I510-M513 WeakPolarHBondContact O-CB 3.39Å; I510-M513 PolarHBondContact O-N 3.4Å; I510-L514 HydrophobicContact CG2-CD1 4.31Å; I510-L514 HydrophobicContact CG2-CG 4.35Å; I510-L514 WeakPolarHBondContact O-CG 3.28Å; I510-L514 PolarHBondContact O-N 2.92Å
511V95.6Very high94.6Very high0 Ų019.9 Ų19.90%012%0.12CC..Hα-helixtrans-63.8-37.3178.31740000111.4L239 L242 L246 L419 L423 W426 H507 C508 M513 L514 N515L239-V511 HydrophobicContact CD2-CG2 4.31Å; L242-V511 HydrophobicContact CD2-CG2 3.72Å; L246-V511 HydrophobicContact CD1-CG1 4.36Å; L419-V511 HydrophobicContact CD1-CB 4.46Å; L419-V511 HydrophobicContact CD1-CG1 3.84Å; L423-V511 HydrophobicContact CD2-CG2 3.95Å; W426-V511 HydrophobicContact CZ3-CG1 4.28Å; H507-V511 WeakPolarHBondContact O-CG2 3.33Å; H507-V511 PolarHBondContact O-N 3.5Å; C508-V511 PolarHBondContact O-N 3.16Å; V511-M513 VanDerWaalsContact C-N 3.27Å; V511-M513 PolarHBondContact O-N 2.92Å; V511-L514 PolarHBondContact O-N 3.46Å; V511-N515 WeakPolarHBondContact O-CB 3.44Å; V511-N515 PolarHBondContact O-N 2.78Å; V511-N515 PolarHBondContact O-ND2 3.11Å
512G94.3Very high94.4Very high2 Ų219.8 Ų19.82%0.02112%0.119CC..Hα-helixtrans-57.7-39170.700000112.6S344 C508 Y509 I510 C516S344-G512 WeakPolarHBondContact CB-O 3.32Å; S344-G512 PolarHBondContact OG-O 3.2Å; C508-G512 PolarHBondContact O-N 3.27Å; Y509-G512 PolarHBondContact O-N 2.87Å; I510-G512 VanDerWaalsContact C-N 3.29Å; I510-G512 PolarHBondContact O-N 3.07Å; G512-C516 VanDerWaalsContact O-CB 3.24Å; G512-C516 WeakPolarHBondContact O-CB 3.28Å; G512-C516 PolarHBondContact O-N 3.25Å
513M95.4Very high94.3Very high0 Ų019.6 Ų19.60%012%0.119CC..Hα-helixtrans-67.8-47.6173.9-177.7-178.5179.300112L232 F347 Y509 I510 V511 N515 C516 L517 F526 Y527L232-M513 HydrophobicContact CD2-CE 4.33Å; L232-M513 HydrophobicContact CD2-SD 4.01Å; F347-M513 HydrophobicContact CB-CB 4.49Å; F347-M513 HydrophobicContact CD1-CB 4.39Å; F347-M513 HydrophobicContact CD2-CB 3.58Å; F347-M513 HydrophobicContact CD2-CG 3.93Å; F347-M513 HydrophobicContact CE1-CG 4.22Å; F347-M513 HydrophobicContact CE2-CB 3.78Å; F347-M513 HydrophobicContact CE2-CG 3.57Å; F347-M513 HydrophobicContact CE2-SD 3.95Å; F347-M513 HydrophobicContact CG-CB 3.91Å; F347-M513 HydrophobicContact CG-CG 4.41Å; F347-M513 HydrophobicContact CZ-CB 4.28Å; F347-M513 HydrophobicContact CZ-CG 3.73Å; F347-M513 HydrophobicContact CZ-SD 4.37Å; Y509-M513 PolarHBondContact O-N 2.98Å; I510-M513 CarbonylContact O-C 3.53Å; I510-M513 WeakPolarHBondContact O-CA 3.5Å; I510-M513 VanDerWaalsContact O-CB 3.27Å; I510-M513 WeakPolarHBondContact O-CB 3.39Å; I510-M513 PolarHBondContact O-N 3.4Å; V511-M513 VanDerWaalsContact C-N 3.27Å; V511-M513 PolarHBondContact O-N 2.92Å; M513-N515 PolarHBondContact O-N 3.42Å; M513-C516 PolarHBondContact O-N 2.79Å; M513-C516 VanDerWaalsContact O-N 3.13Å; M513-L517 HydrophobicContact CE-CD1 3.68Å; M513-L517 HydrophobicContact CG-CD1 3.92Å; M513-L517 WeakPolarHBondContact O-CB 3.28Å; M513-L517 PolarHBondContact O-N 3.15Å; M513-F526 HydrophobicContact CE-CD1 3.88Å; M513-F526 HydrophobicContact CE-CE1 3.42Å; M513-F526 VanDerWaalsContact CE-CE1 3.42Å; M513-F526 HydrophobicContact CE-CZ 3.88Å; M513-Y527 HydrophobicContact CE-CE1 4.23Å; M513-Y527 WeakPolarHBondContact CE-OH 3.31Å
514L95.6Very high94.1Very high0 Ų022 Ų220%013%0.129CC..Hα-helixtrans-61-33.7178.4-61.7-179.3000112.4L242 K250 H253 I510 V511L242-L514 HydrophobicContact CD1-CD1 3.83Å; K250-L514 HydrophobicContact CB-CD1 3.84Å; K250-L514 HydrophobicContact CB-CD2 4.3Å; K250-L514 HydrophobicContact CG-CD1 4.22Å; H253-L514 HydrophobicContact CB-CD2 4.13Å; H253-L514 WeakPolarHBondContact CD2-CD2 3.33Å; I510-L514 HydrophobicContact CG2-CD1 4.31Å; I510-L514 HydrophobicContact CG2-CG 4.35Å; I510-L514 WeakPolarHBondContact O-CG 3.28Å; I510-L514 PolarHBondContact O-N 2.92Å; V511-L514 PolarHBondContact O-N 3.46Å
515N94.1Very high94Very high53 Ų5322.1 Ų22.128%0.28313%0.13SC..Hα-helixtrans-76.4-36.3175.2-74.7-26.2000112.2L246 V511 M513L246-N515 WeakPolarHBondContact CD2-OD1 3.44Å; V511-N515 WeakPolarHBondContact O-CB 3.44Å; V511-N515 PolarHBondContact O-N 2.78Å; V511-N515 PolarHBondContact O-ND2 3.11Å; M513-N515 PolarHBondContact O-N 3.42Å
516C94.6Very high94Very high4 Ų422.1 Ų22.13%0.02713%0.129CC..Hα-helixtrans-69.3-42.5177.6-1760000112.1I342 F347 G512 M513 A518I342-C516 PolarHBondContact N-O 3.46Å; I342-C516 VanDerWaalsContact O-CA 3.29Å; I342-C516 WeakPolarHBondContact O-CA 3.29Å; I342-C516 WeakPolarHBondContact O-CB 3.39Å; I342-C516 PolarHBondContact O-SG 2.73Å; F347-C516 HydrophobicContact CD1-CB 3.57Å; F347-C516 HydrophobicContact CE1-CB 4.11Å; F347-C516 HydrophobicContact CG-CB 4.49Å; G512-C516 VanDerWaalsContact O-CB 3.24Å; G512-C516 WeakPolarHBondContact O-CB 3.28Å; G512-C516 PolarHBondContact O-N 3.25Å; M513-C516 PolarHBondContact O-N 2.79Å; M513-C516 VanDerWaalsContact O-N 3.13Å; C516-A518 PolarHBondContact O-N 2.61Å
517L94.5Very high93.9Very high1 Ų122.3 Ų22.31%0.00513%0.13CC..THydrogen-bonded Turntrans-10058.1-179.6-64171.3000110.4L337 T341 F347 M513 T519 A522 V523 F526L337-L517 HydrophobicContact CD1-CD2 3.87Å; T341-L517 HydrophobicContact CG2-CD2 3.83Å; F347-L517 HydrophobicContact CE1-CD1 4.48Å; F347-L517 HydrophobicContact CZ-CD1 4.43Å; M513-L517 HydrophobicContact CE-CD1 3.68Å; M513-L517 HydrophobicContact CG-CD1 3.92Å; M513-L517 WeakPolarHBondContact O-CB 3.28Å; M513-L517 PolarHBondContact O-N 3.15Å; L517-T519 VanDerWaalsContact C-N 3.3Å; L517-T519 PolarHBondContact O-N 3.33Å; L517-A522 HydrophobicContact CD2-CB 3.9Å; L517-V523 HydrophobicContact CB-CG2 4.04Å; L517-V523 WeakPolarHBondContact O-CG2 3.48Å; L517-F526 HydrophobicContact CD1-CB 4.03Å; L517-F526 HydrophobicContact CD1-CD1 4.13Å; L517-F526 HydrophobicContact CD1-CD2 3.9Å; L517-F526 HydrophobicContact CD1-CE2 4.42Å; L517-F526 HydrophobicContact CD1-CG 3.75Å; L517-F526 HydrophobicContact CD2-CB 4.19Å; L517-F526 HydrophobicContact CD2-CD2 4.45Å
518A91.2Very high93.7Very high35 Ų3525.6 Ų25.629%0.28914%0.144SC..  trans-71.4-18.8-17000000114.9I342 C516I342-A518 HydrophobicContact CD1-CB 4.01Å; C516-A518 PolarHBondContact O-N 2.61Å
519T91.6Very high93.7Very high70 Ų7025.8 Ų25.843%0.42915%0.145SC..SBendtrans-108.5147.7-176.669.60000111.7L517 E521 A522 V523L517-T519 VanDerWaalsContact C-N 3.3Å; L517-T519 PolarHBondContact O-N 3.33Å; T519-E521 PolarHBondContact O-N 3.16Å; T519-A522 PolarHBondContact O-N 3.38Å; T519-A522 VanDerWaalsContact O-N 3.11Å; T519-A522 WeakPolarHBondContact OG1-CB 3.24Å; T519-A522 PolarHBondContact OG1-N 3.38Å; T519-V523 WeakPolarHBondContact O-CG2 3.47Å; T519-V523 PolarHBondContact O-N 3.29Å
520A90.4Very high93.5Very high72 Ų7225.6 Ų25.660%0.59515%0.145SC*.Hα-helixtrans-57.6-33176.500000112.7H524A520-H524 VanDerWaalsContact O-CB 3.29Å; A520-H524 WeakPolarHBondContact O-CB 3.43Å; A520-H524 PolarHBondContact O-N 3.45Å
521E90.6Very high93.2Very high106 Ų10626 Ų2650%0.49515%0.147SC..Hα-helixtrans-65.2-45.2175.6-176.1178.317700112.3T519 H524 T525T519-E521 PolarHBondContact O-N 3.16Å; E521-H524 PolarHBondContact O-N 2.93Å; E521-T525 VanDerWaalsContact O-CB 3.3Å; E521-T525 WeakPolarHBondContact O-CB 3.47Å; E521-T525 PolarHBondContact O-N 3Å; E521-T525 PolarHBondContact O-OG1 3.18Å
522A93Very high93.2Very high0 Ų026.3 Ų26.30%015%0.148CC..Hα-helixtrans-63.5-43.7177.100000111.1N340 L517 T519 T525 F526N340-A522 HydrophobicContact CB-CB 4.47Å; L517-A522 HydrophobicContact CD2-CB 3.9Å; T519-A522 PolarHBondContact O-N 3.38Å; T519-A522 VanDerWaalsContact O-N 3.11Å; T519-A522 WeakPolarHBondContact OG1-CB 3.24Å; T519-A522 PolarHBondContact OG1-N 3.38Å; A522-T525 PolarHBondContact O-N 3.23Å; A522-F526 WeakPolarHBondContact O-CB 3.41Å; A522-F526 PolarHBondContact O-N 3.1Å
523V94.3Very high93.1Very high5 Ų526.5 Ų26.53%0.0315%0.148CC..Hα-helixtrans-59.3-49.9176.1-179.70000111.3V252 H253 A256 L517 T519 T525 F526 Y527V252-V523 HydrophobicContact CG1-CG1 4.14Å; H253-V523 VanDerWaalsContact NE2-CG2 3.26Å; H253-V523 WeakPolarHBondContact NE2-CG2 3.49Å; A256-V523 HydrophobicContact CB-CG1 4.23Å; L517-V523 HydrophobicContact CB-CG2 4.04Å; L517-V523 WeakPolarHBondContact O-CG2 3.48Å; T519-V523 WeakPolarHBondContact O-CG2 3.47Å; T519-V523 PolarHBondContact O-N 3.29Å; V523-T525 VanDerWaalsContact C-N 3.35Å; V523-T525 PolarHBondContact O-N 3.18Å; V523-F526 PolarHBondContact O-N 3.06Å; V523-Y527 HydrophobicContact CG1-CD2 3.73Å; V523-Y527 HydrophobicContact CG1-CE2 3.5Å; V523-Y527 VanDerWaalsContact CG1-CE2 3.5Å; V523-Y527 WeakPolarHBondContact O-CD2 3.43Å; V523-Y527 PolarHBondContact O-N 2.78Å; V523-Y527 VanDerWaalsContact O-N 3.13Å
524H91.6Very high92.9Very high96 Ų9627.6 Ų27.644%0.44416%0.157SC..Hα-helixtrans-62.1-43179-174.359.8000112.1A520 E521 K528A520-H524 VanDerWaalsContact O-CB 3.29Å; A520-H524 WeakPolarHBondContact O-CB 3.43Å; A520-H524 PolarHBondContact O-N 3.45Å; E521-H524 PolarHBondContact O-N 2.93Å; H524-K528 WeakPolarHBondContact CE1-CE 3.45Å; H524-K528 WeakPolarHBondContact NE2-CE 3.45Å; H524-K528 PolarHBondContact NE2-NZ 3.23Å; H524-K528 VanDerWaalsContact O-CB 3.28Å; H524-K528 WeakPolarHBondContact O-CB 3.36Å; H524-K528 WeakPolarHBondContact O-CG 3.42Å; H524-K528 PolarHBondContact O-N 3.06Å
525T93.4Very high92.7Very high3 Ų327.6 Ų27.62%0.01816%0.158CC..Hα-helixtrans-63.6-43.6178.4-58.10000110.9L337 E521 A522 V523 K528 L529L337-T525 HydrophobicContact CB-CG2 4.24Å; L337-T525 HydrophobicContact CD1-CG2 4.37Å; E521-T525 VanDerWaalsContact O-CB 3.3Å; E521-T525 WeakPolarHBondContact O-CB 3.47Å; E521-T525 PolarHBondContact O-N 3Å; E521-T525 PolarHBondContact O-OG1 3.18Å; A522-T525 PolarHBondContact O-N 3.23Å; V523-T525 VanDerWaalsContact C-N 3.35Å; V523-T525 PolarHBondContact O-N 3.18Å; T525-K528 PolarHBondContact O-N 3.31Å; T525-L529 WeakPolarHBondContact O-CB 3.35Å; T525-L529 PolarHBondContact O-N 3.01Å
526F94.8Very high92.7Very high0 Ų025.1 Ų25.10%014%0.144CC..Hα-helixtrans-59.7-48.7178-178.5-90.8000112.4L337 F347 L351 V354 M513 L517 A522 V523 L529 L530L337-F526 HydrophobicContact CD1-CB 4.2Å; L337-F526 HydrophobicContact CD2-CB 4.46Å; L337-F526 HydrophobicContact CD2-CD2 4.02Å; F347-F526 AromaticContact CZ-CE2 3.96Å; F347-F526 HydrophobicContact CZ-CE2 3.96Å; F347-F526 HydrophobicContact CZ-CZ 4.21Å; L351-F526 HydrophobicContact CD2-CD2 4.32Å; L351-F526 HydrophobicContact CD2-CE1 3.87Å; L351-F526 HydrophobicContact CD2-CE2 3.62Å; L351-F526 HydrophobicContact CD2-CZ 3.37Å; L351-F526 HydrophobicContact CG-CE2 4.24Å; L351-F526 HydrophobicContact CG-CZ 4.43Å; V354-F526 HydrophobicContact CG2-CZ 4.38Å; M513-F526 HydrophobicContact CE-CD1 3.88Å; M513-F526 HydrophobicContact CE-CE1 3.42Å; M513-F526 VanDerWaalsContact CE-CE1 3.42Å; M513-F526 HydrophobicContact CE-CZ 3.88Å; L517-F526 HydrophobicContact CD1-CB 4.03Å; L517-F526 HydrophobicContact CD1-CD1 4.13Å; L517-F526 HydrophobicContact CD1-CD2 3.9Å; L517-F526 HydrophobicContact CD1-CE2 4.42Å; L517-F526 HydrophobicContact CD1-CG 3.75Å; L517-F526 HydrophobicContact CD2-CB 4.19Å; L517-F526 HydrophobicContact CD2-CD2 4.45Å; A522-F526 WeakPolarHBondContact O-CB 3.41Å; A522-F526 PolarHBondContact O-N 3.1Å; V523-F526 PolarHBondContact O-N 3.06Å; F526-L529 WeakPolarHBondContact O-CB 3.5Å; F526-L529 PolarHBondContact O-N 3.3Å; F526-L530 PolarHBondContact O-N 2.95Å
527Y93.4Very high92.6Very high6 Ų625.7 Ų25.72%0.02415%0.147CC..Hα-helixtrans-77.2-30.6-179-64.2-59.1000113.4H253 A256 L257 M513 V523 L529 L530 C531H253-Y527 HydrophobicContact CB-CE2 4.38Å; H253-Y527 AromaticContact ND1-CE2 3.86Å; H253-Y527 AromaticContact ND1-CZ 3.8Å; H253-Y527 PolarHBondContact ND1-OH 3.37Å; A256-Y527 HydrophobicContact CB-CD2 3.36Å; A256-Y527 HydrophobicContact CB-CE2 3.76Å; A256-Y527 HydrophobicContact CB-CG 4.22Å; L257-Y527 HydrophobicContact CB-CD1 4.17Å; L257-Y527 HydrophobicContact CB-CE1 3.65Å; L257-Y527 HydrophobicContact CB-CE2 4.39Å; L257-Y527 HydrophobicContact CD1-CD1 4.01Å; L257-Y527 HydrophobicContact CD1-CE1 3.81Å; L257-Y527 HydrophobicContact CD2-CE1 4.41Å; L257-Y527 HydrophobicContact CG-CE1 4.15Å; M513-Y527 HydrophobicContact CE-CE1 4.23Å; M513-Y527 WeakPolarHBondContact CE-OH 3.31Å; V523-Y527 HydrophobicContact CG1-CD2 3.73Å; V523-Y527 HydrophobicContact CG1-CE2 3.5Å; V523-Y527 VanDerWaalsContact CG1-CE2 3.5Å; V523-Y527 WeakPolarHBondContact O-CD2 3.43Å; V523-Y527 PolarHBondContact O-N 2.78Å; V523-Y527 VanDerWaalsContact O-N 3.13Å; Y527-L529 VanDerWaalsContact C-N 3.32Å; Y527-L530 HydrophobicContact CD1-CD2 4.37Å; Y527-L530 WeakPolarHBondContact O-CB 3.46Å; Y527-L530 PolarHBondContact O-N 2.97Å; Y527-C531 WeakPolarHBondContact O-CB 3.42Å; Y527-C531 PolarHBondContact O-N 3.07Å
528K93Very high92.4Very high77 Ų7726 Ų2634%0.33515%0.149SC..Hα-helixtrans-62.6-41.1167.1-82.5-172159.4-1750111.7M333 H524 T525 L530 C531 R532M333-K528 HydrophobicContact CE-CB 3.87Å; H524-K528 WeakPolarHBondContact CE1-CE 3.45Å; H524-K528 WeakPolarHBondContact NE2-CE 3.45Å; H524-K528 PolarHBondContact NE2-NZ 3.23Å; H524-K528 VanDerWaalsContact O-CB 3.28Å; H524-K528 WeakPolarHBondContact O-CB 3.36Å; H524-K528 WeakPolarHBondContact O-CG 3.42Å; H524-K528 PolarHBondContact O-N 3.06Å; T525-K528 PolarHBondContact O-N 3.31Å; K528-L530 VanDerWaalsContact C-N 3.33Å; K528-C531 PolarHBondContact O-N 3.25Å; K528-R532 WeakPolarHBondContact O-CB 3.34Å; K528-R532 PolarHBondContact O-N 3.28Å
529L94Very high92.5Very high4 Ų424.3 Ų24.32%0.02114%0.135CC..Hα-helixtrans-60.8-44.3175.6-176.571.3000110.3L330 M333 V334 L337 L351 T525 F526 Y527 R532 Y533L330-L529 HydrophobicContact CD2-CD1 3.61Å; M333-L529 HydrophobicContact CB-CD1 3.7Å; M333-L529 HydrophobicContact CE-CB 4.01Å; M333-L529 HydrophobicContact CE-CD1 4.38Å; M333-L529 HydrophobicContact SD-CD1 4.34Å; V334-L529 HydrophobicContact CG2-CD1 4.05Å; V334-L529 HydrophobicContact CG2-CD2 3.82Å; L337-L529 HydrophobicContact CD2-CD2 3.87Å; L351-L529 HydrophobicContact CD1-CB 4.08Å; L351-L529 HydrophobicContact CD1-CD2 3.59Å; L351-L529 HydrophobicContact CD1-CG 3.55Å; L351-L529 HydrophobicContact CG-CD2 4.22Å; T525-L529 WeakPolarHBondContact O-CB 3.35Å; T525-L529 PolarHBondContact O-N 3.01Å; F526-L529 WeakPolarHBondContact O-CB 3.5Å; F526-L529 PolarHBondContact O-N 3.3Å; Y527-L529 VanDerWaalsContact C-N 3.32Å; L529-R532 PolarHBondContact O-N 3.46Å; L529-Y533 HydrophobicContact CD1-CD2 4.08Å; L529-Y533 HydrophobicContact CD1-CE2 3.86Å; L529-Y533 HydrophobicContact CD2-CE2 4.29Å; L529-Y533 HydrophobicContact CG-CD2 3.89Å; L529-Y533 HydrophobicContact CG-CE2 3.89Å; L529-Y533 WeakPolarHBondContact O-CD2 3.39Å; L529-Y533 PolarHBondContact O-N 3.37Å
530L92.1Very high92.6Very high3 Ų321 Ų212%0.01612%0.115CC..Hα-helixtrans-57.3-53.4174.6170.958.7000112.2W229 L257 L351 F526 Y527 K528 R532 Y533 A534 L626W229-L530 HydrophobicContact CD2-CD1 4.23Å; W229-L530 HydrophobicContact CD2-CD2 3.85Å; W229-L530 VanDerWaalsContact CE2-CD1 3.43Å; W229-L530 HydrophobicContact CE3-CD2 4.27Å; W229-L530 HydrophobicContact CG-CD2 4.06Å; W229-L530 HydrophobicContact CZ2-CD1 3.65Å; W229-L530 HydrophobicContact CZ2-CD2 4.4Å; W229-L530 VanDerWaalsContact NE1-CD1 3.27Å; L257-L530 HydrophobicContact CD1-CD2 4.14Å; L351-L530 HydrophobicContact CD1-CB 4.27Å; L351-L530 HydrophobicContact CD2-CB 4.19Å; F526-L530 PolarHBondContact O-N 2.95Å; Y527-L530 HydrophobicContact CD1-CD2 4.37Å; Y527-L530 WeakPolarHBondContact O-CB 3.46Å; Y527-L530 PolarHBondContact O-N 2.97Å; K528-L530 VanDerWaalsContact C-N 3.33Å; L530-R532 VanDerWaalsContact C-N 3.31Å; L530-R532 PolarHBondContact O-N 2.71Å; L530-Y533 PolarHBondContact O-N 2.71Å; L530-A534 PolarHBondContact O-N 3.42Å; L530-L626 HydrophobicContact CD1-CD1 4.34Å
531C90.5Very high92.8Very high8 Ų817.6 Ų17.65%0.0549%0.087CC..Hα-helixtrans-59.8-40.9179.2-950000111.3C260 Y527 K528 A534 I535C260-C531 VanDerWaalsContact CA-SG 3.58Å; C260-C531 WeakPolarHBondContact CB-SG 3.26Å; C260-C531 WeakPolarHBondContact SG-CB 3.35Å; C260-C531 CovalentContact SG-SG 2.07Å; C260-C531 PolarHBondContact SG-SG 3.13Å; Y527-C531 WeakPolarHBondContact O-CB 3.42Å; Y527-C531 PolarHBondContact O-N 3.07Å; K528-C531 PolarHBondContact O-N 3.25Å; C531-A534 PolarHBondContact O-N 3.32Å; C531-I535 WeakPolarHBondContact O-CG1 3.14Å; C531-I535 PolarHBondContact O-N 3.23Å; C531-I535 VanDerWaalsContact O-N 3.14Å
532R93.9Very high92.8Very high7 Ų712.6 Ų12.63%0.0266%0.064CC..Hα-helixtrans-62.5-49.8174.6-169.3171.7-164.11057.4111.4T319 A320 G324 L330 K528 L529 L530 A534 I535 V536 D592T319-R532 PolarHBondContact OG1-NH2 2.82Å; T319-R532 VanDerWaalsContact OG1-NH2 3.16Å; A320-R532 HydrophobicContact CB-CG 3.83Å; G324-R532 PolarHBondContact O-NH1 2.84Å; L330-R532 HydrophobicContact CD2-CB 3.95Å; L330-R532 HydrophobicContact CD2-CG 3.72Å; L330-R532 HydrophobicContact CG-CG 4.19Å; K528-R532 WeakPolarHBondContact O-CB 3.34Å; K528-R532 PolarHBondContact O-N 3.28Å; L529-R532 PolarHBondContact O-N 3.46Å; L530-R532 VanDerWaalsContact C-N 3.31Å; L530-R532 PolarHBondContact O-N 2.71Å; R532-A534 VanDerWaalsContact C-N 3.29Å; R532-A534 PolarHBondContact O-N 2.85Å; R532-I535 PolarHBondContact O-N 3.35Å; R532-V536 HydrophobicContact CG-CG2 4.04Å; R532-V536 VanDerWaalsContact O-CG2 3.22Å; R532-V536 WeakPolarHBondContact O-CG2 3.33Å; R532-V536 PolarHBondContact O-N 2.88Å; R532-D592 IonicContact CZ-OD1 2.73Å; R532-D592 IonicContact CZ-OD2 3.88Å; R532-D592 VanDerWaalsContact CZ-OD2 3.26Å; R532-D592 IonicContact NE-OD1 2.74Å; R532-D592 PolarHBondContact NE-OD1 2.97Å; R532-D592 IonicContact NE-OD2 3.56Å; R532-D592 PolarHBondContact NE-OD2 3.01Å; R532-D592 IonicContact NH2-OD1 2.71Å; R532-D592 IonicContact NH2-OD2 2.91Å; R532-D592 PolarHBondContact NH2-OD2 3.33Å
533Y93.2Very high92.9Very high6 Ų612.6 Ų12.62%0.0246%0.064CC..Hα-helixtrans-53.1-46.3175.8-98.4-75.2000112L330 L351 K352 L529 L530 I535 V536 L537 E595 M596 L599 L626L330-Y533 HydrophobicContact CD1-CD1 4.17Å; L330-Y533 HydrophobicContact CD1-CE1 4.1Å; L330-Y533 HydrophobicContact CD1-CG 4.44Å; L330-Y533 HydrophobicContact CD2-CD1 4.48Å; L330-Y533 HydrophobicContact CD2-CD2 3.6Å; L330-Y533 HydrophobicContact CD2-CE2 3.76Å; L330-Y533 HydrophobicContact CD2-CG 3.99Å; L351-Y533 HydrophobicContact CD1-CD2 3.56Å; L351-Y533 HydrophobicContact CD1-CE2 3.96Å; L351-Y533 HydrophobicContact CD1-CG 4.5Å; K352-Y533 WeakPolarHBondContact CE-OH 3.41Å; K352-Y533 PolarHBondContact NZ-OH 3.39Å; L529-Y533 HydrophobicContact CD1-CD2 4.08Å; L529-Y533 HydrophobicContact CD1-CE2 3.86Å; L529-Y533 HydrophobicContact CD2-CE2 4.29Å; L529-Y533 HydrophobicContact CG-CD2 3.89Å; L529-Y533 HydrophobicContact CG-CE2 3.89Å; L529-Y533 WeakPolarHBondContact O-CD2 3.39Å; L529-Y533 PolarHBondContact O-N 3.37Å; L530-Y533 PolarHBondContact O-N 2.71Å; Y533-I535 PolarHBondContact O-N 3.37Å; Y533-V536 PolarHBondContact O-N 2.8Å; Y533-L537 WeakPolarHBondContact O-CB 3.38Å; Y533-L537 PolarHBondContact O-N 3.21Å; Y533-E595 PolarHBondContact OH-OE2 2.9Å; Y533-M596 HydrophobicContact CD1-CE 3.54Å; Y533-M596 HydrophobicContact CE1-CE 3.52Å; Y533-L599 HydrophobicContact CD1-CD1 4.08Å; Y533-L599 HydrophobicContact CE1-CD1 3.91Å; Y533-L626 HydrophobicContact CD1-CD2 4.02Å; Y533-L626 HydrophobicContact CG-CD1 4.27Å; Y533-L626 HydrophobicContact CG-CD2 4.35Å
534A90.3Very high93Very high23 Ų2312.5 Ų12.519%0.196%0.063CC..Hα-helixtrans-60.8-44.6-179.900000112.1L264 F292 L530 C531 R532 S538L264-A534 HydrophobicContact CD2-CB 3.81Å; F292-A534 HydrophobicContact CE1-CB 4Å; F292-A534 HydrophobicContact CZ-CB 4.37Å; L530-A534 PolarHBondContact O-N 3.42Å; C531-A534 PolarHBondContact O-N 3.32Å; R532-A534 VanDerWaalsContact C-N 3.29Å; R532-A534 PolarHBondContact O-N 2.85Å; A534-S538 WeakPolarHBondContact O-CB 3.48Å; A534-S538 PolarHBondContact O-N 3.07Å; A534-S538 VanDerWaalsContact O-N 3.1Å
535I91.3Very high93.1Very high1 Ų18 Ų81%0.0054%0.042CC..Hα-helixtrans-62.4-55.7177-70.3164.5000110.6A291 F292 A320 E323 C531 R532 Y533 L537 S538 Q539A291-I535 HydrophobicContact CB-CD1 4.04Å; A291-I535 HydrophobicContact CB-CG1 4.2Å; A291-I535 HydrophobicContact CB-CG2 4.44Å; A291-I535 VanDerWaalsContact O-CG2 3.25Å; A291-I535 WeakPolarHBondContact O-CG2 3.21Å; F292-I535 HydrophobicContact CD2-CG1 4.14Å; F292-I535 HydrophobicContact CE1-CG1 4.06Å; F292-I535 HydrophobicContact CE2-CD1 4.44Å; F292-I535 HydrophobicContact CE2-CG1 3.62Å; F292-I535 HydrophobicContact CZ-CG1 3.53Å; A320-I535 HydrophobicContact CB-CB 4.17Å; A320-I535 HydrophobicContact CB-CD1 3.96Å; A320-I535 HydrophobicContact CB-CG2 3.84Å; E323-I535 HydrophobicContact CG-CD1 4.02Å; C531-I535 WeakPolarHBondContact O-CG1 3.14Å; C531-I535 PolarHBondContact O-N 3.23Å; C531-I535 VanDerWaalsContact O-N 3.14Å; R532-I535 PolarHBondContact O-N 3.35Å; Y533-I535 PolarHBondContact O-N 3.37Å; I535-L537 VanDerWaalsContact C-N 3.33Å; I535-L537 PolarHBondContact O-N 2.9Å; I535-S538 PolarHBondContact O-N 3.32Å; I535-Q539 VanDerWaalsContact CG2-NE2 3.34Å; I535-Q539 WeakPolarHBondContact O-CG 3.42Å; I535-Q539 PolarHBondContact O-N 3.21Å; I535-Q539 VanDerWaalsContact O-N 3.16Å
536V94.4Very high93.1Very high0 Ų08.1 Ų8.10%04%0.043CC..Hα-helixtrans-66-39.2-173.2-166.50000110.9F318 L330 R532 Y533 Q539 A540 D592 M596F318-V536 VanDerWaalsContact C-CG1 3.48Å; F318-V536 HydrophobicContact CB-CG1 3.53Å; F318-V536 WeakPolarHBondContact O-CG1 3.37Å; L330-V536 HydrophobicContact CD1-CB 4.5Å; L330-V536 HydrophobicContact CD1-CG2 4.42Å; R532-V536 HydrophobicContact CG-CG2 4.04Å; R532-V536 VanDerWaalsContact O-CG2 3.22Å; R532-V536 WeakPolarHBondContact O-CG2 3.33Å; R532-V536 PolarHBondContact O-N 2.88Å; Y533-V536 PolarHBondContact O-N 2.8Å; V536-Q539 PolarHBondContact O-N 3.26Å; V536-A540 WeakPolarHBondContact O-CB 3.5Å; V536-A540 PolarHBondContact O-N 2.99Å; V536-D592 HydrophobicContact CG1-CB 4.15Å; V536-D592 HydrophobicContact CG2-CB 4.35Å; V536-M596 HydrophobicContact CB-CG 3.99Å; V536-M596 HydrophobicContact CB-SD 4Å; V536-M596 HydrophobicContact CG1-CG 3.23Å; V536-M596 HydrophobicContact CG1-SD 3.93Å
537L92.4Very high93.2Very high17 Ų178.1 Ų8.19%0.0894%0.043CC..Hα-helixtrans-62.3-44.5176.3177.163.1000112Y533 I535 Q539 A540 L541 M596 L599 L626 I629Y533-L537 WeakPolarHBondContact O-CB 3.38Å; Y533-L537 PolarHBondContact O-N 3.21Å; I535-L537 VanDerWaalsContact C-N 3.33Å; I535-L537 PolarHBondContact O-N 2.9Å; L537-Q539 VanDerWaalsContact C-N 3.32Å; L537-Q539 PolarHBondContact O-N 3.33Å; L537-A540 PolarHBondContact O-N 3.47Å; L537-L541 HydrophobicContact CD1-CD1 3.74Å; L537-L541 HydrophobicContact CD1-CG 3.75Å; L537-L541 HydrophobicContact CD2-CD1 4.33Å; L537-L541 HydrophobicContact CG-CD1 3.77Å; L537-L541 HydrophobicContact CG-CG 4.2Å; L537-L541 WeakPolarHBondContact O-CB 3.4Å; L537-L541 PolarHBondContact O-N 3.1Å; L537-M596 HydrophobicContact CB-SD 4.08Å; L537-L599 HydrophobicContact CD1-CD2 3.61Å; L537-L626 HydrophobicContact CD2-CD2 3.82Å; L537-I629 HydrophobicContact CD1-CD1 3.75Å; L537-I629 HydrophobicContact CD2-CD1 3.45Å; L537-I629 VanDerWaalsContact CD2-CD1 3.45Å; L537-I629 HydrophobicContact CG-CD1 4.17Å
538S90.3Very high93.4Very high7 Ų77.9 Ų7.95%0.0494%0.042CC..Hα-helixtrans-58-46.1177.2177.70000111.3F292 A534 I535 A540 T542F292-S538 PolarHBondContact O-OG 3.09Å; A534-S538 WeakPolarHBondContact O-CB 3.48Å; A534-S538 PolarHBondContact O-N 3.07Å; A534-S538 VanDerWaalsContact O-N 3.1Å; I535-S538 PolarHBondContact O-N 3.32Å; S538-A540 PolarHBondContact O-N 3.46Å; S538-T542 VanDerWaalsContact O-CB 3.27Å; S538-T542 WeakPolarHBondContact O-CB 3.32Å; S538-T542 PolarHBondContact O-N 3.22Å; S538-T542 PolarHBondContact O-OG1 2.77Å
539Q93.1Very high93.5Very high0 Ų04.7 Ų4.70%03%0.029CC..Hα-helixtrans-62.2-45177.9-62.3174.512.200111.6A291 P294 F318 T319 I535 V536 L537 S543A291-Q539 PolarHBondContact O-NE2 3.17Å; P294-Q539 HydrophobicContact CB-CB 4.2Å; P294-Q539 HydrophobicContact CG-CB 4.27Å; F318-Q539 VanDerWaalsContact CA-OE1 3.22Å; F318-Q539 HydrophobicContact CB-CB 4.34Å; F318-Q539 HydrophobicContact CD1-CB 3.9Å; F318-Q539 HydrophobicContact CG-CB 4.44Å; T319-Q539 PolarHBondContact O-NE2 3.41Å; T319-Q539 PolarHBondContact O-OE1 3.37Å; I535-Q539 VanDerWaalsContact CG2-NE2 3.34Å; I535-Q539 WeakPolarHBondContact O-CG 3.42Å; I535-Q539 PolarHBondContact O-N 3.21Å; I535-Q539 VanDerWaalsContact O-N 3.16Å; V536-Q539 PolarHBondContact O-N 3.26Å; L537-Q539 VanDerWaalsContact C-N 3.32Å; L537-Q539 PolarHBondContact O-N 3.33Å; Q539-S543 PolarHBondContact O-N 3.19Å; Q539-S543 PolarHBondContact O-OG 3.15Å
540A95Very high93.5Very high0 Ų04.6 Ų4.60%03%0.028CC..Hα-helixtrans-68.6-49-177.800000111.7F318 V536 L537 S538 T542 S543 I544 M596 L600F318-A540 HydrophobicContact CB-CB 4.43Å; F318-A540 HydrophobicContact CD2-CB 3.59Å; F318-A540 HydrophobicContact CE2-CB 3.91Å; F318-A540 HydrophobicContact CG-CB 3.94Å; V536-A540 WeakPolarHBondContact O-CB 3.5Å; V536-A540 PolarHBondContact O-N 2.99Å; L537-A540 PolarHBondContact O-N 3.47Å; S538-A540 PolarHBondContact O-N 3.46Å; A540-T542 PolarHBondContact O-N 3.15Å; A540-S543 PolarHBondContact O-N 2.79Å; A540-I544 WeakPolarHBondContact O-CG1 3.36Å; A540-I544 PolarHBondContact O-N 2.94Å; A540-M596 HydrophobicContact CB-CB 4.25Å; A540-M596 HydrophobicContact CB-CG 4.29Å; A540-L600 HydrophobicContact CB-CD1 3.94Å
541L93.2Very high93.7Very high1 Ų14.6 Ų4.61%0.0053%0.028CC..Hα-helixtrans-59.2-45.5176.4-80.5175.2000111.8C224 L537 S543 I544 V545 L600 V622 I629 V631C224-L541 HydrophobicContact CB-CB 4.48Å; C224-L541 HydrophobicContact CB-CD1 4.33Å; L537-L541 HydrophobicContact CD1-CD1 3.74Å; L537-L541 HydrophobicContact CD1-CG 3.75Å; L537-L541 HydrophobicContact CD2-CD1 4.33Å; L537-L541 HydrophobicContact CG-CD1 3.77Å; L537-L541 HydrophobicContact CG-CG 4.2Å; L537-L541 WeakPolarHBondContact O-CB 3.4Å; L537-L541 PolarHBondContact O-N 3.1Å; L541-S543 PolarHBondContact O-N 2.97Å; L541-I544 PolarHBondContact O-N 3.38Å; L541-V545 WeakPolarHBondContact O-CB 3.25Å; L541-V545 VanDerWaalsContact O-CG2 3.26Å; L541-V545 WeakPolarHBondContact O-CG2 3.41Å; L541-V545 PolarHBondContact O-N 3.17Å; L541-L600 HydrophobicContact CD2-CD2 3.63Å; L541-L600 HydrophobicContact CG-CD2 4.14Å; L541-V622 HydrophobicContact CD1-CG1 4.37Å; L541-I629 HydrophobicContact CD1-CD1 4.48Å; L541-I629 HydrophobicContact CD1-CG2 4.12Å; L541-V631 HydrophobicContact CD2-CG2 4.3Å
542T91.6Very high93.9Very high1 Ų14.2 Ų4.21%0.0063%0.026CC..Hα-helixtrans-59-41179.1-57.60000111.2L221 L222 P294 L297 S538 A540 S546L221-T542 HydrophobicContact CD2-CG2 3.6Å; L222-T542 HydrophobicContact CB-CG2 4.49Å; P294-T542 HydrophobicContact CG-CG2 4.32Å; L297-T542 HydrophobicContact CD2-CG2 4.35Å; S538-T542 VanDerWaalsContact O-CB 3.27Å; S538-T542 WeakPolarHBondContact O-CB 3.32Å; S538-T542 PolarHBondContact O-N 3.22Å; S538-T542 PolarHBondContact O-OG1 2.77Å; A540-T542 PolarHBondContact O-N 3.15Å; T542-S546 WeakPolarHBondContact O-CB 3.44Å; T542-S546 PolarHBondContact O-N 3.42Å; T542-S546 PolarHBondContact O-OG 2.92Å
543S94.6Very high93.8Very high0 Ų04.3 Ų4.30%03%0.026CC..Hα-helixtrans-67.8-46.3178.1-53.90000111.9F318 Q539 A540 L541 S546 V547F318-S543 VanDerWaalsContact CE1-OG 3.23Å; F318-S543 WeakPolarHBondContact CE1-OG 3.36Å; Q539-S543 PolarHBondContact O-N 3.19Å; Q539-S543 PolarHBondContact O-OG 3.15Å; A540-S543 PolarHBondContact O-N 2.79Å; L541-S543 PolarHBondContact O-N 2.97Å; S543-S546 WeakPolarHBondContact O-CB 3.37Å; S543-S546 PolarHBondContact O-N 3.35Å; S543-V547 WeakPolarHBondContact O-CG2 3.49Å; S543-V547 PolarHBondContact O-N 3.18Å; S543-V547 VanDerWaalsContact O-N 3.15Å
544I96.1Very high93.7Very high3 Ų34.3 Ų4.32%0.0153%0.026CC..Hα-helixtrans-65.2-43.5178.4-64.4-56.4000111.7A540 L541 S546 V547 L548 V574 L600 F606 V655 V657A540-I544 WeakPolarHBondContact O-CG1 3.36Å; A540-I544 PolarHBondContact O-N 2.94Å; L541-I544 PolarHBondContact O-N 3.38Å; I544-S546 VanDerWaalsContact C-N 3.28Å; I544-S546 PolarHBondContact O-N 2.79Å; I544-V547 WeakPolarHBondContact O-CB 3.02Å; I544-V547 PolarHBondContact O-N 3.21Å; I544-V547 VanDerWaalsContact O-N 3.17Å; I544-L548 HydrophobicContact CG2-CD1 4.25Å; I544-L548 HydrophobicContact CG2-CG 4.49Å; I544-L548 WeakPolarHBondContact O-CG 3.35Å; I544-L548 PolarHBondContact O-N 3.5Å; I544-V574 HydrophobicContact CD1-CB 4.24Å; I544-V574 HydrophobicContact CD1-CG1 3.76Å; I544-V574 HydrophobicContact CD1-CG2 4.42Å; I544-L600 HydrophobicContact CG1-CD1 3.92Å; I544-F606 HydrophobicContact CG2-CZ 4.12Å; I544-V655 HydrophobicContact CG2-CG1 4.02Å; I544-V655 HydrophobicContact CG2-CG2 4.41Å; I544-V657 HydrophobicContact CD1-CG2 3.88Å; I544-V657 HydrophobicContact CG1-CG2 4.35Å
545V94.5Very high93.8Very high0 Ų03.6 Ų3.60%02%0.02CC..Hα-helixtrans-64.3-37.6177.6176.20000110.9L222 L541 V547 L548 L549 F606 P620 V631 L633L222-V545 HydrophobicContact CD1-CB 3.5Å; L222-V545 HydrophobicContact CD1-CG1 3.23Å; L222-V545 HydrophobicContact CD1-CG2 4.23Å; L541-V545 WeakPolarHBondContact O-CB 3.25Å; L541-V545 VanDerWaalsContact O-CG2 3.26Å; L541-V545 WeakPolarHBondContact O-CG2 3.41Å; L541-V545 PolarHBondContact O-N 3.17Å; V545-V547 VanDerWaalsContact C-N 3.28Å; V545-V547 PolarHBondContact O-N 2.96Å; V545-L548 PolarHBondContact O-N 2.75Å; V545-L549 HydrophobicContact CG1-CD1 3.75Å; V545-L549 HydrophobicContact CG1-CG 3.95Å; V545-L549 WeakPolarHBondContact O-CB 3.42Å; V545-L549 WeakPolarHBondContact O-CG 3.23Å; V545-L549 PolarHBondContact O-N 3.43Å; V545-F606 HydrophobicContact CG2-CE1 4.08Å; V545-P620 HydrophobicContact CG1-CB 4.1Å; V545-P620 HydrophobicContact CG1-CG 3.88Å; V545-V631 HydrophobicContact CG2-CG1 3.88Å; V545-L633 HydrophobicContact CG1-CD2 3.52Å; V545-L633 HydrophobicContact CG2-CD2 4.33Å
546S93.8Very high93.7Very high6 Ų66.3 Ų6.34%0.0424%0.035CC..Hα-helixtrans-59.5-39.8174.5-59.40000112.1P219 F313 T542 S543 I544 N550P219-S546 WeakPolarHBondContact CB-OG 3.24Å; F313-S546 WeakPolarHBondContact CZ-O 3.27Å; T542-S546 WeakPolarHBondContact O-CB 3.44Å; T542-S546 PolarHBondContact O-N 3.42Å; T542-S546 PolarHBondContact O-OG 2.92Å; S543-S546 WeakPolarHBondContact O-CB 3.37Å; S543-S546 PolarHBondContact O-N 3.35Å; I544-S546 VanDerWaalsContact C-N 3.28Å; I544-S546 PolarHBondContact O-N 2.79Å; S546-N550 WeakPolarHBondContact O-CB 3.38Å; S546-N550 PolarHBondContact O-N 2.9Å
547V96.6Very high93.5Very high0 Ų011.1 Ų11.10%06%0.061CC..Hα-helixtrans-60.9-52.2174173.90000110.8F313 S543 I544 V545 L549 N550 V551 V574 D745 V747F313-V547 HydrophobicContact CB-CG2 4.11Å; F313-V547 HydrophobicContact CD1-CG2 4.03Å; F313-V547 HydrophobicContact CD2-CB 4.28Å; F313-V547 HydrophobicContact CD2-CG2 3.46Å; F313-V547 VanDerWaalsContact CD2-CG2 3.46Å; F313-V547 HydrophobicContact CE1-CG2 4.36Å; F313-V547 HydrophobicContact CE2-CB 4.19Å; F313-V547 HydrophobicContact CE2-CG1 4.49Å; F313-V547 HydrophobicContact CE2-CG2 3.85Å; F313-V547 HydrophobicContact CG-CG2 3.56Å; F313-V547 HydrophobicContact CZ-CG2 4.28Å; S543-V547 WeakPolarHBondContact O-CG2 3.49Å; S543-V547 PolarHBondContact O-N 3.18Å; S543-V547 VanDerWaalsContact O-N 3.15Å; I544-V547 WeakPolarHBondContact O-CB 3.02Å; I544-V547 PolarHBondContact O-N 3.21Å; I544-V547 VanDerWaalsContact O-N 3.17Å; V545-V547 VanDerWaalsContact C-N 3.28Å; V545-V547 PolarHBondContact O-N 2.96Å; V547-L549 PolarHBondContact O-N 2.78Å; V547-N550 WeakPolarHBondContact O-CB 3.48Å; V547-N550 PolarHBondContact O-N 2.85Å; V547-V551 PolarHBondContact O-N 2.92Å; V547-V551 VanDerWaalsContact O-N 3.09Å; V547-V574 HydrophobicContact CG1-CG2 4.22Å; V547-D745 HydrophobicContact CG1-CB 3.39Å; V547-V747 HydrophobicContact CG2-CG2 3.75Å
548L97.2Very high93.4Very high1 Ų116.7 Ų16.71%0.0059%0.086CC..Hα-helixtrans-65.2-41.1-176.7-60.9177000112I544 V545 N550 V551 L552 W567 A572 F606 L633 V655I544-L548 HydrophobicContact CG2-CD1 4.25Å; I544-L548 HydrophobicContact CG2-CG 4.49Å; I544-L548 WeakPolarHBondContact O-CG 3.35Å; I544-L548 PolarHBondContact O-N 3.5Å; V545-L548 PolarHBondContact O-N 2.75Å; L548-N550 VanDerWaalsContact C-N 3.33Å; L548-N550 PolarHBondContact O-N 3.2Å; L548-V551 PolarHBondContact O-N 2.89Å; L548-L552 VanDerWaalsContact O-CG 3.32Å; L548-L552 WeakPolarHBondContact O-CG 3.3Å; L548-L552 PolarHBondContact O-N 2.9Å; L548-W567 HydrophobicContact CB-CH2 4.11Å; L548-W567 HydrophobicContact CD2-CH2 3.74Å; L548-W567 HydrophobicContact CD2-CZ2 3.57Å; L548-W567 HydrophobicContact CD2-CZ3 4.44Å; L548-A572 HydrophobicContact CD2-CB 3.95Å; L548-F606 HydrophobicContact CD1-CD1 3.59Å; L548-F606 HydrophobicContact CD1-CE1 3.73Å; L548-F606 HydrophobicContact CD1-CG 4.11Å; L548-F606 HydrophobicContact CD1-CZ 4.35Å; L548-L633 HydrophobicContact CB-CD1 3.63Å; L548-L633 HydrophobicContact CD1-CD1 3.73Å; L548-L633 HydrophobicContact CG-CD1 4.35Å; L548-V655 HydrophobicContact CD1-CG2 3.86Å; L548-V655 HydrophobicContact CD2-CG2 4.48Å
549L94.7Very high93.4Very high10 Ų1019.4 Ų19.45%0.05210%0.098CC..Hα-helixtrans-63.5-39.4174.8-71.2177.1000111.4L192 V545 V547 V551 L552 W553 P620 L633 P634L192-L549 HydrophobicContact CD1-CB 4.35Å; L192-L549 HydrophobicContact CD2-CB 4.09Å; L192-L549 HydrophobicContact CD2-CD1 4.23Å; V545-L549 HydrophobicContact CG1-CD1 3.75Å; V545-L549 HydrophobicContact CG1-CG 3.95Å; V545-L549 WeakPolarHBondContact O-CB 3.42Å; V545-L549 WeakPolarHBondContact O-CG 3.23Å; V545-L549 PolarHBondContact O-N 3.43Å; V547-L549 PolarHBondContact O-N 2.78Å; L549-V551 VanDerWaalsContact C-N 3.31Å; L549-V551 PolarHBondContact O-N 3.46Å; L549-L552 PolarHBondContact O-N 3.36Å; L549-W553 WeakPolarHBondContact O-CB 3.45Å; L549-W553 PolarHBondContact O-N 3.33Å; L549-P620 HydrophobicContact CD1-CG 4.43Å; L549-L633 HydrophobicContact CD2-CB 4.35Å; L549-L633 HydrophobicContact CD2-CD2 4.36Å; L549-P634 HydrophobicContact CD2-CG 4.45Å
550N94.6Very high93.5Very high3 Ų319.4 Ų19.42%0.01610%0.098CC..Hα-helixtrans-60.7-40.7174.5-179.673.3000112.2F193 D311 F313 S546 V547 L548 M554 A555F193-N550 HydrophobicContact CZ-CB 4.03Å; F193-N550 WeakPolarHBondContact CZ-OD1 3.33Å; D311-N550 PolarHBondContact OD2-ND2 3.48Å; F313-N550 HydrophobicContact CE2-CB 4.08Å; F313-N550 HydrophobicContact CZ-CB 3.6Å; S546-N550 WeakPolarHBondContact O-CB 3.38Å; S546-N550 PolarHBondContact O-N 2.9Å; V547-N550 WeakPolarHBondContact O-CB 3.48Å; V547-N550 PolarHBondContact O-N 2.85Å; L548-N550 VanDerWaalsContact C-N 3.33Å; L548-N550 PolarHBondContact O-N 3.2Å; N550-M554 WeakPolarHBondContact O-CA 3.35Å; N550-M554 WeakPolarHBondContact O-CB 3.22Å; N550-M554 PolarHBondContact O-N 3.37Å; N550-M554 WeakPolarHBondContact OD1-CB 3.37Å; N550-A555 PolarHBondContact O-N 3.3Å
551V96Very high93.5Very high2 Ų223.2 Ų23.21%0.01212%0.118CC..Hα-helixtrans-62.1-49.3173.7173.30000110.9V547 L548 L549 W553 A555 K563 W567 D745V547-V551 PolarHBondContact O-N 2.92Å; V547-V551 VanDerWaalsContact O-N 3.09Å; L548-V551 PolarHBondContact O-N 2.89Å; L549-V551 VanDerWaalsContact C-N 3.31Å; L549-V551 PolarHBondContact O-N 3.46Å; V551-W553 VanDerWaalsContact C-N 3.26Å; V551-W553 PolarHBondContact O-N 3.5Å; V551-A555 HydrophobicContact CG1-CB 4.46Å; V551-A555 VanDerWaalsContact O-CB 3.23Å; V551-A555 WeakPolarHBondContact O-CB 3.19Å; V551-A555 PolarHBondContact O-N 2.77Å; V551-K563 HydrophobicContact CB-CD 4.34Å; V551-K563 HydrophobicContact CG1-CB 3.88Å; V551-K563 HydrophobicContact CG1-CD 3.56Å; V551-K563 HydrophobicContact CG1-CG 4.35Å; V551-K563 HydrophobicContact CG2-CD 3.8Å; V551-W567 HydrophobicContact CB-CH2 3.85Å; V551-W567 HydrophobicContact CB-CZ2 3.82Å; V551-W567 HydrophobicContact CG1-CH2 3.77Å; V551-W567 HydrophobicContact CG1-CZ2 3.61Å; V551-W567 HydrophobicContact CG2-CZ2 4.13Å; V551-D745 WeakPolarHBondContact CG2-OD2 3.26Å
552L95Very high93.5Very high0 Ų024.2 Ų24.20%012%0.123CC..Hα-helixtrans-63.6-29.7-175.3-71.6169.4000113.5L548 L549 F560 T564 W567 L608 L633 V635 R639L548-L552 VanDerWaalsContact O-CG 3.32Å; L548-L552 WeakPolarHBondContact O-CG 3.3Å; L548-L552 PolarHBondContact O-N 2.9Å; L549-L552 PolarHBondContact O-N 3.36Å; L552-F560 HydrophobicContact CD2-CE2 3.99Å; L552-T564 HydrophobicContact CD2-CG2 4.37Å; L552-W567 HydrophobicContact CD1-CZ3 4.27Å; L552-W567 HydrophobicContact CD2-CH2 4.25Å; L552-W567 HydrophobicContact CD2-CZ3 3.74Å; L552-W567 HydrophobicContact CG-CH2 4.03Å; L552-W567 HydrophobicContact CG-CZ3 3.89Å; L552-L608 HydrophobicContact CD1-CD2 3.77Å; L552-L608 HydrophobicContact CD2-CD1 3.98Å; L552-L608 HydrophobicContact CD2-CD2 4.26Å; L552-L633 HydrophobicContact CD1-CB 4.01Å; L552-L633 HydrophobicContact CD1-CD1 4.15Å; L552-V635 HydrophobicContact CD1-CG2 4.17Å; L552-V635 HydrophobicContact CD2-CG1 4.44Å; L552-V635 HydrophobicContact CD2-CG2 3.94Å; L552-R639 WeakPolarHBondContact O-CD 3.46Å
553W92Very high93.7Very high10 Ų1024.8 Ų24.84%0.03813%0.126CC..Hα-helixtrans-113.3-25.6-170.7-7071.4000114.7H188 L191 L192 L549 V551 M611 C618 P634 P636H188-W553 HydrophobicContact CB-CE3 4.04Å; H188-W553 AromaticContact CD2-CE3 3.74Å; H188-W553 AromaticContact CD2-CZ3 3.85Å; H188-W553 AromaticContact CG-CE3 3.72Å; H188-W553 PolarHBondContact ND1-O 3.36Å; H188-W553 VanDerWaalsContact ND1-O 3.08Å; L191-W553 HydrophobicContact CD2-CE3 4.09Å; L191-W553 HydrophobicContact CD2-CH2 3.41Å; L191-W553 VanDerWaalsContact CD2-CH2 3.41Å; L191-W553 HydrophobicContact CD2-CZ2 4.23Å; L191-W553 HydrophobicContact CD2-CZ3 3.33Å; L192-W553 HydrophobicContact CD1-CB 3.44Å; L192-W553 VanDerWaalsContact CD1-CB 3.44Å; L192-W553 HydrophobicContact CD1-CD2 4.37Å; L192-W553 HydrophobicContact CD1-CG 3.7Å; L192-W553 HydrophobicContact CD2-CD2 4.47Å; L192-W553 HydrophobicContact CD2-CG 4.39Å; L192-W553 HydrophobicContact CG-CB 4.38Å; L192-W553 HydrophobicContact CG-CD2 4.48Å; L192-W553 HydrophobicContact CG-CG 4.28Å; L549-W553 WeakPolarHBondContact O-CB 3.45Å; L549-W553 PolarHBondContact O-N 3.33Å; V551-W553 VanDerWaalsContact C-N 3.26Å; V551-W553 PolarHBondContact O-N 3.5Å; W553-M611 HydrophobicContact CH2-CE 4Å; W553-M611 HydrophobicContact CH2-SD 3.41Å; W553-M611 WeakPolarHBondContact CH2-SD 3.35Å; W553-M611 HydrophobicContact CZ2-SD 3.54Å; W553-M611 VanDerWaalsContact CZ2-SD 3.54Å; W553-C618 HydrophobicContact CH2-CB 4.37Å; W553-C618 HydrophobicContact CZ2-CB 3.99Å; W553-P634 PolarHBondContact NE1-O 3.24Å; W553-P636 HydrophobicContact CD2-CG 3.51Å; W553-P636 HydrophobicContact CE3-CG 3.56Å; W553-P636 HydrophobicContact CG-CG 4Å; W553-P636 HydrophobicContact CH2-CG 3.99Å; W553-P636 HydrophobicContact CZ2-CG 3.99Å; W553-P636 HydrophobicContact CZ3-CB 4.46Å; W553-P636 HydrophobicContact CZ3-CG 3.78Å
554M90.8Very high93.7Very high5 Ų524.8 Ų24.83%0.02513%0.126CC..Hα-helixtrans-126.3-10.2-168.2-55.2-61.2-54.900114.9M181 E185 H188 L192 F193 K309 N550M181-M554 HydrophobicContact SD-CE 4.46Å; E185-M554 HydrophobicContact CB-CE 4.27Å; H188-M554 HydrophobicContact CB-SD 3.58Å; H188-M554 VanDerWaalsContact CB-SD 3.58Å; L192-M554 HydrophobicContact CD1-CG 4.21Å; F193-M554 HydrophobicContact CE2-CG 3.93Å; K309-M554 PolarHBondContact NZ-O 3.28Å; N550-M554 WeakPolarHBondContact O-CA 3.35Å; N550-M554 WeakPolarHBondContact O-CB 3.22Å; N550-M554 PolarHBondContact O-N 3.37Å; N550-M554 WeakPolarHBondContact OD1-CB 3.37Å
555A91.9Very high93.7Very high8 Ų825.9 Ų25.97%0.06613%0.134CC..SBendtrans-67.9148.1173.600000109.9N550 V551 Q559 F560 R639N550-A555 PolarHBondContact O-N 3.3Å; V551-A555 HydrophobicContact CG1-CB 4.46Å; V551-A555 VanDerWaalsContact O-CB 3.23Å; V551-A555 WeakPolarHBondContact O-CB 3.19Å; V551-A555 PolarHBondContact O-N 2.77Å; A555-Q559 HydrophobicContact CB-CB 4.15Å; A555-F560 HydrophobicContact CB-CB 4.27Å; A555-R639 PolarHBondContact O-NH1 2.94Å; A555-R639 PolarHBondContact O-NH2 3.45Å
556D89.4Confident93.7Very high59 Ų5926 Ų2632%0.31613%0.134SC..  trans-64166.2165.757.275.4000111.1E558 Q559 F560D556-E558 VanDerWaalsContact C-N 3.3Å; D556-E558 PolarHBondContact O-N 3.04Å; D556-E558 PolarHBondContact OD1-N 3.32Å; D556-Q559 PolarHBondContact O-N 3.49Å; D556-Q559 WeakPolarHBondContact OD1-CB 3.25Å; D556-Q559 WeakPolarHBondContact OD1-CG 3.35Å; D556-Q559 PolarHBondContact OD1-N 3.27Å; D556-Q559 WeakPolarHBondContact OD2-CG 3.24Å; D556-F560 WeakPolarHBondContact O-CB 3.48Å; D556-F560 PolarHBondContact O-N 2.8Å
557D90.2Very high93.9Very high101 Ų10125.9 Ų25.954%0.5413%0.133SC..Hα-helixtrans-63-35.7-172.9-64.8-15.9000112.7L561 R639D557-L561 WeakPolarHBondContact O-CB 3.16Å; D557-L561 WeakPolarHBondContact O-CG 3.4Å; D557-L561 PolarHBondContact O-N 2.81Å; D557-R639 IonicContact OD1-NH2 3.45Å; D557-R639 PolarHBondContact OD1-NH2 3.24Å
558E89.9Confident93.8Very high134 Ų13427.3 Ų27.363%0.62614%0.143SC*.Hα-helixtrans-65.6-51.2178.2-175.6-177.2168.800110.6D556 F560 L561 L562D556-E558 VanDerWaalsContact C-N 3.3Å; D556-E558 PolarHBondContact O-N 3.04Å; D556-E558 PolarHBondContact OD1-N 3.32Å; E558-F560 VanDerWaalsContact C-N 3.34Å; E558-F560 PolarHBondContact O-N 2.68Å; E558-L561 PolarHBondContact O-N 3.47Å; E558-L562 WeakPolarHBondContact O-CB 3.3Å; E558-L562 PolarHBondContact O-N 3Å
559Q91.9Very high93.6Very high63 Ų6332.4 Ų32.429%0.29417%0.166SC..Hα-helixtrans-64.6-38.1177.1-70.5-61-5100112A555 D556 K563A555-Q559 HydrophobicContact CB-CB 4.15Å; D556-Q559 PolarHBondContact O-N 3.49Å; D556-Q559 WeakPolarHBondContact OD1-CB 3.25Å; D556-Q559 WeakPolarHBondContact OD1-CG 3.35Å; D556-Q559 PolarHBondContact OD1-N 3.27Å; D556-Q559 WeakPolarHBondContact OD2-CG 3.24Å; Q559-K563 WeakPolarHBondContact O-CB 3.25Å; Q559-K563 WeakPolarHBondContact O-CD 3.45Å; Q559-K563 WeakPolarHBondContact O-CG 3.35Å; Q559-K563 PolarHBondContact O-N 3.19Å
560F94.6Very high93.5Very high0 Ų032.4 Ų32.40%017%0.167CC..Hα-helixtrans-61.4-49.3176.9175.1-90.7000111.5L552 A555 D556 E558 T564 R639 I642 L643L552-F560 HydrophobicContact CD2-CE2 3.99Å; A555-F560 HydrophobicContact CB-CB 4.27Å; D556-F560 WeakPolarHBondContact O-CB 3.48Å; D556-F560 PolarHBondContact O-N 2.8Å; E558-F560 VanDerWaalsContact C-N 3.34Å; E558-F560 PolarHBondContact O-N 2.68Å; F560-T564 HydrophobicContact CD2-CG2 4.24Å; F560-T564 HydrophobicContact CE1-CG2 4.31Å; F560-T564 HydrophobicContact CE2-CG2 4Å; F560-T564 HydrophobicContact CZ-CG2 4.03Å; F560-T564 WeakPolarHBondContact O-CB 3.34Å; F560-T564 VanDerWaalsContact O-CG2 3.3Å; F560-T564 WeakPolarHBondContact O-CG2 3.32Å; F560-T564 PolarHBondContact O-N 3.42Å; F560-T564 PolarHBondContact O-OG1 3.5Å; F560-R639 VanDerWaalsContact CD2-NH1 3.34Å; F560-R639 HydrophobicContact CE1-CB 4.35Å; F560-R639 HydrophobicContact CE2-CB 4.17Å; F560-R639 HydrophobicContact CZ-CB 3.8Å; F560-R639 HydrophobicContact CZ-CG 4.47Å; F560-I642 HydrophobicContact CD1-CD1 3.71Å; F560-I642 HydrophobicContact CD1-CG1 4.34Å; F560-I642 HydrophobicContact CE1-CD1 3.63Å; F560-I642 HydrophobicContact CE1-CG1 3.77Å; F560-L643 HydrophobicContact CE1-CD2 3.95Å; F560-L643 HydrophobicContact CE1-CG 4.45Å; F560-L643 HydrophobicContact CE2-CD2 4.37Å; F560-L643 HydrophobicContact CZ-CD2 3.47Å; F560-L643 VanDerWaalsContact CZ-CD2 3.47Å; F560-L643 HydrophobicContact CZ-CG 4.04Å
561L94.1Very high93.6Very high81 Ų8132.6 Ų32.642%0.42417%0.17SC..Hα-helixtrans-64.4-46.3179.8-72.2171.8000111.6D557 E558 K563 T564 S565 I642D557-L561 WeakPolarHBondContact O-CB 3.16Å; D557-L561 WeakPolarHBondContact O-CG 3.4Å; D557-L561 PolarHBondContact O-N 2.81Å; E558-L561 PolarHBondContact O-N 3.47Å; L561-K563 PolarHBondContact O-N 3.2Å; L561-T564 PolarHBondContact O-OG1 3Å; L561-S565 WeakPolarHBondContact O-CB 3.18Å; L561-S565 PolarHBondContact O-N 3.42Å; L561-I642 HydrophobicContact CD2-CB 4.24Å; L561-I642 HydrophobicContact CD2-CD1 4.32Å; L561-I642 VanDerWaalsContact CD2-O 3.32Å; L561-I642 WeakPolarHBondContact CD2-O 3.43Å
562L93.1Very high93.7Very high21 Ų2132.5 Ų32.511%0.1117%0.169CC..Hα-helixtrans-57.8-51.9176.7175.362.8000111.3E558 S565 L566 E702 F705E558-L562 WeakPolarHBondContact O-CB 3.3Å; E558-L562 PolarHBondContact O-N 3Å; L562-S565 PolarHBondContact O-N 3.41Å; L562-L566 HydrophobicContact CD1-CD1 4.09Å; L562-L566 HydrophobicContact CG-CD1 4.16Å; L562-L566 WeakPolarHBondContact O-CD1 3.23Å; L562-L566 VanDerWaalsContact O-CG 3.31Å; L562-L566 WeakPolarHBondContact O-CG 3.48Å; L562-L566 PolarHBondContact O-N 3.15Å; L562-L566 VanDerWaalsContact O-N 3.1Å; L562-E702 HydrophobicContact CD1-CG 3.64Å; L562-F705 HydrophobicContact CD1-CE1 4.04Å
563K95.7Very high93.9Very high13 Ų1332.7 Ų32.76%0.05717%0.17CC..Hα-helixtrans-63.9-48-177-72.2174175.7-82.10111.4V551 Q559 L561 S565 L566 W567 G743 G744 D745V551-K563 HydrophobicContact CB-CD 4.34Å; V551-K563 HydrophobicContact CG1-CB 3.88Å; V551-K563 HydrophobicContact CG1-CD 3.56Å; V551-K563 HydrophobicContact CG1-CG 4.35Å; V551-K563 HydrophobicContact CG2-CD 3.8Å; Q559-K563 WeakPolarHBondContact O-CB 3.25Å; Q559-K563 WeakPolarHBondContact O-CD 3.45Å; Q559-K563 WeakPolarHBondContact O-CG 3.35Å; Q559-K563 PolarHBondContact O-N 3.19Å; L561-K563 PolarHBondContact O-N 3.2Å; K563-S565 PolarHBondContact O-N 3.38Å; K563-L566 WeakPolarHBondContact O-CB 3.41Å; K563-L566 PolarHBondContact O-N 3.05Å; K563-W567 PolarHBondContact O-N 3.27Å; K563-W567 PolarHBondContact O-NE1 3.38Å; K563-G743 WeakPolarHBondContact CG-O 3.18Å; K563-G743 PolarHBondContact NZ-O 3.26Å; K563-G744 PolarHBondContact NZ-O 3.16Å; K563-D745 IonicContact NZ-OD1 3.81Å; K563-D745 PolarHBondContact NZ-OD1 2.97Å; K563-D745 IonicContact NZ-OD2 3.39Å; K563-D745 PolarHBondContact NZ-OD2 2.76Å
564T96.3Very high94.2Very high0 Ų032.2 Ų32.20%017%0.168CC..Hα-helixtrans-69.3-33.2-178.3570000112.7L552 F560 L561 W567 S568 L643 L647L552-T564 HydrophobicContact CD2-CG2 4.37Å; F560-T564 HydrophobicContact CD2-CG2 4.24Å; F560-T564 HydrophobicContact CE1-CG2 4.31Å; F560-T564 HydrophobicContact CE2-CG2 4Å; F560-T564 HydrophobicContact CZ-CG2 4.03Å; F560-T564 WeakPolarHBondContact O-CB 3.34Å; F560-T564 VanDerWaalsContact O-CG2 3.3Å; F560-T564 WeakPolarHBondContact O-CG2 3.32Å; F560-T564 PolarHBondContact O-N 3.42Å; F560-T564 PolarHBondContact O-OG1 3.5Å; L561-T564 PolarHBondContact O-OG1 3Å; T564-W567 HydrophobicContact CG2-CE3 4.28Å; T564-W567 HydrophobicContact CG2-CZ3 4.46Å; T564-W567 PolarHBondContact O-N 3.13Å; T564-S568 PolarHBondContact O-N 3.08Å; T564-S568 VanDerWaalsContact O-N 3.11Å; T564-L643 HydrophobicContact CG2-CD2 3.65Å; T564-L647 WeakPolarHBondContact O-CD1 3.38Å
565S94.7Very high94.5Very high26 Ų2632 Ų3218%0.18217%0.168CC..Hα-helixtrans-56.1-49.1167.7177.50000111.3L561 L562 K563 W567 S568 H569 E702L561-S565 WeakPolarHBondContact O-CB 3.18Å; L561-S565 PolarHBondContact O-N 3.42Å; L562-S565 PolarHBondContact O-N 3.41Å; K563-S565 PolarHBondContact O-N 3.38Å; S565-W567 PolarHBondContact O-N 3.25Å; S565-S568 WeakPolarHBondContact O-CB 3.33Å; S565-S568 PolarHBondContact O-N 2.99Å; S565-H569 PolarHBondContact O-N 3.44Å; S565-H569 PolarHBondContact O-ND1 2.98Å; S565-E702 PolarHBondContact OG-OE2 3.42Å
566L95.6Very high94.9Very high3 Ų331.9 Ų31.92%0.01617%0.166CC..Hα-helixtrans-64.2-38.9177.5-68.2163.9000112L562 K563 S568 H569 S570 G571 A698 E702 F705 L742L562-L566 HydrophobicContact CD1-CD1 4.09Å; L562-L566 HydrophobicContact CG-CD1 4.16Å; L562-L566 WeakPolarHBondContact O-CD1 3.23Å; L562-L566 VanDerWaalsContact O-CG 3.31Å; L562-L566 WeakPolarHBondContact O-CG 3.48Å; L562-L566 PolarHBondContact O-N 3.15Å; L562-L566 VanDerWaalsContact O-N 3.1Å; K563-L566 WeakPolarHBondContact O-CB 3.41Å; K563-L566 PolarHBondContact O-N 3.05Å; L566-S568 VanDerWaalsContact C-N 3.29Å; L566-S568 PolarHBondContact O-N 2.87Å; L566-H569 PolarHBondContact O-N 2.83Å; L566-S570 CarbonylContact O-C 3.55Å; L566-S570 WeakPolarHBondContact O-CA 3.2Å; L566-S570 PolarHBondContact O-N 3.45Å; L566-G571 PolarHBondContact O-N 3Å; L566-A698 HydrophobicContact CD2-CB 3.88Å; L566-E702 HydrophobicContact CD2-CB 4.4Å; L566-F705 HydrophobicContact CD1-CZ 3.94Å; L566-F705 HydrophobicContact CD2-CE2 4.14Å; L566-F705 HydrophobicContact CD2-CZ 3.91Å; L566-F705 HydrophobicContact CG-CZ 4.5Å; L566-L742 WeakPolarHBondContact CD1-O 3.49Å
567W96.7Very high95.3Very high4 Ų429.1 Ų29.12%0.01515%0.151CC..Hα-helixtrans-60.4-41178.4-64.34.9000111.9L548 V551 L552 K563 T564 S565 G571 A572 L647 F653L548-W567 HydrophobicContact CB-CH2 4.11Å; L548-W567 HydrophobicContact CD2-CH2 3.74Å; L548-W567 HydrophobicContact CD2-CZ2 3.57Å; L548-W567 HydrophobicContact CD2-CZ3 4.44Å; V551-W567 HydrophobicContact CB-CH2 3.85Å; V551-W567 HydrophobicContact CB-CZ2 3.82Å; V551-W567 HydrophobicContact CG1-CH2 3.77Å; V551-W567 HydrophobicContact CG1-CZ2 3.61Å; V551-W567 HydrophobicContact CG2-CZ2 4.13Å; L552-W567 HydrophobicContact CD1-CZ3 4.27Å; L552-W567 HydrophobicContact CD2-CH2 4.25Å; L552-W567 HydrophobicContact CD2-CZ3 3.74Å; L552-W567 HydrophobicContact CG-CH2 4.03Å; L552-W567 HydrophobicContact CG-CZ3 3.89Å; K563-W567 PolarHBondContact O-N 3.27Å; K563-W567 PolarHBondContact O-NE1 3.38Å; T564-W567 HydrophobicContact CG2-CE3 4.28Å; T564-W567 HydrophobicContact CG2-CZ3 4.46Å; T564-W567 PolarHBondContact O-N 3.13Å; S565-W567 PolarHBondContact O-N 3.25Å; W567-G571 WeakPolarHBondContact O-CA 3.2Å; W567-G571 PolarHBondContact O-N 3.47Å; W567-A572 VanDerWaalsContact CD1-CA 3.4Å; W567-A572 HydrophobicContact CD2-CB 4.11Å; W567-A572 HydrophobicContact CG-CB 3.87Å; W567-A572 VanDerWaalsContact NE1-CB 3.35Å; W567-L647 HydrophobicContact CB-CD1 4.42Å; W567-F653 HydrophobicContact CB-CD2 4.07Å; W567-F653 HydrophobicContact CB-CE2 4.31Å; W567-F653 HydrophobicContact CB-CG 4.36Å; W567-F653 HydrophobicContact CD2-CE2 4.06Å; W567-F653 HydrophobicContact CD2-CZ 4.32Å; W567-F653 HydrophobicContact CE3-CE1 4.32Å; W567-F653 AromaticContact CE3-CE2 3.86Å; W567-F653 HydrophobicContact CE3-CE2 3.86Å; W567-F653 AromaticContact CE3-CZ 3.64Å; W567-F653 HydrophobicContact CE3-CZ 3.64Å; W567-F653 HydrophobicContact CG-CD2 4.42Å; W567-F653 HydrophobicContact CG-CE2 4.27Å; W567-F653 HydrophobicContact CZ3-CZ 4.08Å; W567-F653 VanDerWaalsContact O-CB 3.29Å; W567-F653 WeakPolarHBondContact O-CB 3.48Å
568S95Very high95.7Very high29 Ų2924.3 Ų24.320%0.20313%0.125CC..Hα-helixtrans-60-45.2176.6172.10000112.6T564 S565 L566 S646T564-S568 PolarHBondContact O-N 3.08Å; T564-S568 VanDerWaalsContact O-N 3.11Å; S565-S568 WeakPolarHBondContact O-CB 3.33Å; S565-S568 PolarHBondContact O-N 2.99Å; L566-S568 VanDerWaalsContact C-N 3.29Å; L566-S568 PolarHBondContact O-N 2.87Å; S568-S646 WeakPolarHBondContact CB-OG 3.26Å; S568-S646 PolarHBondContact OG-OG 3.18Å
569H92.4Very high96Very high108 Ų10818 Ų1850%0.510%0.096SC..Hα-helixtrans-102-33.5-167.7-57.5102.1000114.5S565 L566 Q701S565-H569 PolarHBondContact O-N 3.44Å; S565-H569 PolarHBondContact O-ND1 2.98Å; L566-H569 PolarHBondContact O-N 2.83Å; H569-Q701 HydrophobicContact CB-CG 4.29Å
570S94.3Very high96.3Very high11 Ų1115 Ų158%0.0778%0.082CC..Hα-helixtrans-122.5-7.4-173.1-60.60000113.5L566 H656 Y694 S697L566-S570 CarbonylContact O-C 3.55Å; L566-S570 WeakPolarHBondContact O-CA 3.2Å; L566-S570 PolarHBondContact O-N 3.45Å; S570-H656 PolarHBondContact O-CD2 3.3Å; S570-H656 VanDerWaalsContact O-CD2 3.23Å; S570-H656 PolarHBondContact O-NE2 3.34Å; S570-Y694 WeakPolarHBondContact O-CE2 3.36Å; S570-S697 PolarHBondContact OG-OG 3.16Å
571G96.5Very high96.4Very high6 Ų615 Ų156%0.0628%0.082CC..  trans80.6167-170.800000112.6L566 W567 Q654 Y694L566-G571 PolarHBondContact O-N 3Å; W567-G571 WeakPolarHBondContact O-CA 3.2Å; W567-G571 PolarHBondContact O-N 3.47Å; G571-Q654 CarbonylContact C-O 3.55Å; G571-Q654 WeakPolarHBondContact CA-O 3.15Å; G571-Y694 WeakPolarHBondContact O-CE2 3.34Å; G571-Y694 PolarHBondContact O-OH 3.5Å
572A98Very high96.5Very high1 Ų111.1 Ų11.11%0.0086%0.061CC..EExtended strand (participates in β ladder)trans-81.7131.3179.900000111.3L548 W567 F653 Q654 V655 H656L548-A572 HydrophobicContact CD2-CB 3.95Å; W567-A572 VanDerWaalsContact CD1-CA 3.4Å; W567-A572 HydrophobicContact CD2-CB 4.11Å; W567-A572 HydrophobicContact CG-CB 3.87Å; W567-A572 VanDerWaalsContact NE1-CB 3.35Å; A572-F653 HydrophobicContact CB-CD2 4.41Å; A572-F653 HydrophobicContact CB-CE2 4.16Å; A572-Q654 PolarHBondContact N-O 3.49Å; A572-V655 HydrophobicContact CB-CG1 4.48Å; A572-V655 HydrophobicContact CB-CG2 4.09Å; A572-V655 CarbonylContact O-C 3.51Å; A572-V655 WeakPolarHBondContact O-CA 3.43Å; A572-H656 PolarHBondContact O-N 2.86Å
573L98.3Very high96.5Very high3 Ų311.8 Ų11.82%0.0166%0.064CC..EExtended strand (participates in β ladder)trans-92.3125.5175.2178.864.1000111.2H656 I658 L691 Y694 C739 L742 G744 D745L573-H656 HydrophobicContact CD1-CB 4.35Å; L573-I658 HydrophobicContact CD1-CD1 3.61Å; L573-I658 HydrophobicContact CD1-CG1 3.99Å; L573-L691 HydrophobicContact CD1-CD1 4.44Å; L573-L691 HydrophobicContact CD2-CD1 4Å; L573-Y694 HydrophobicContact CB-CD1 4.3Å; L573-Y694 HydrophobicContact CB-CD2 4.49Å; L573-Y694 HydrophobicContact CB-CE1 3.76Å; L573-Y694 HydrophobicContact CB-CE2 3.96Å; L573-Y694 HydrophobicContact CD1-CD1 4.33Å; L573-Y694 HydrophobicContact CD1-CD2 4.45Å; L573-Y694 HydrophobicContact CD1-CG 4.24Å; L573-Y694 HydrophobicContact CD2-CD1 3.79Å; L573-Y694 HydrophobicContact CD2-CE1 3.75Å; L573-Y694 HydrophobicContact CG-CD1 4.37Å; L573-Y694 HydrophobicContact CG-CE1 4.24Å; L573-C739 HydrophobicContact CD2-CB 4.47Å; L573-L742 HydrophobicContact CD2-CB 4.01Å; L573-L742 HydrophobicContact CD2-CD1 4.45Å; L573-G744 WeakPolarHBondContact O-CA 3.33Å; L573-D745 PolarHBondContact O-N 3.17Å
574V98.6Very high96.4Very high0 Ų016.1 Ų16.10%09%0.087CC..EExtended strand (participates in β ladder)trans-127.9118.4170.3-179.10000109.4I544 V547 V655 H656 V657 I658 D745 V747I544-V574 HydrophobicContact CD1-CB 4.24Å; I544-V574 HydrophobicContact CD1-CG1 3.76Å; I544-V574 HydrophobicContact CD1-CG2 4.42Å; V547-V574 HydrophobicContact CG1-CG2 4.22Å; V574-V655 HydrophobicContact CB-CG1 4.36Å; V574-V655 HydrophobicContact CG2-CG1 3.83Å; V574-H656 PolarHBondContact N-O 3.21Å; V574-V657 WeakPolarHBondContact O-CA 3.5Å; V574-I658 PolarHBondContact O-N 3.21Å; V574-D745 CarbonylContact C-O 3.58Å; V574-D745 WeakPolarHBondContact CA-O 3.5Å; V574-V747 HydrophobicContact CG1-CG2 3.69Å
575S98.2Very high96.3Very high2 Ų217.9 Ų17.91%0.01410%0.099CC..EExtended strand (participates in β ladder)trans-94.2115176.8-165.60000110.2H577 W660 C739 D745 V746 V747S575-H577 WeakPolarHBondContact CB-NE2 3.34Å; S575-H577 PolarHBondContact O-CD2 2.84Å; S575-H577 PolarHBondContact OG-CE1 3.26Å; S575-H577 PolarHBondContact OG-NE2 2.9Å; S575-W660 VanDerWaalsContact OG-CD1 3.23Å; S575-W660 PolarHBondContact OG-NE1 2.79Å; S575-C739 WeakPolarHBondContact CB-SG 3.34Å; S575-D745 PolarHBondContact N-O 3.49Å; S575-V746 WeakPolarHBondContact O-CA 3.45Å; S575-V747 PolarHBondContact O-N 3.36Å
576L98.6Very high96.3Very high5 Ų516.9 Ų16.93%0.0269%0.092CC..EExtended strand (participates in β ladder)trans-99.4112.9-179.5176.460.9000109.6F318 L593 V657 I658 L659 W660 V747 C749F318-L576 HydrophobicContact CD2-CD2 4.46Å; F318-L576 HydrophobicContact CE2-CD1 4.29Å; F318-L576 HydrophobicContact CE2-CD2 3.98Å; L576-L593 HydrophobicContact CD2-CD2 4.32Å; L576-V657 HydrophobicContact CB-CG1 4.14Å; L576-V657 HydrophobicContact CD2-CG1 4.37Å; L576-I658 PolarHBondContact N-O 3.35Å; L576-L659 HydrophobicContact CB-CD1 4.41Å; L576-L659 HydrophobicContact CD2-CD1 3.89Å; L576-L659 HydrophobicContact CG-CD1 3.86Å; L576-L659 CarbonylContact O-C 3.29Å; L576-L659 WeakPolarHBondContact O-CA 3.5Å; L576-W660 PolarHBondContact O-N 2.72Å; L576-V747 CarbonylContact C-O 3.17Å; L576-V747 WeakPolarHBondContact CA-O 3.29Å; L576-V747 HydrophobicContact CD1-CB 3.79Å; L576-V747 HydrophobicContact CD1-CG1 3.58Å; L576-C749 HydrophobicContact CD1-CB 4.46Å
577H98.5Very high96.3Very high1 Ų119.8 Ų19.81%0.00510%0.102CC..EExtended strand (participates in β ladder)trans-106.8110.4-177.5-64.1-88.7000111.1S575 W660 T732 M736 V747 I748 C749S575-H577 WeakPolarHBondContact CB-NE2 3.34Å; S575-H577 PolarHBondContact O-CD2 2.84Å; S575-H577 PolarHBondContact OG-CE1 3.26Å; S575-H577 PolarHBondContact OG-NE2 2.9Å; H577-W660 AromaticContact CE1-CD1 3.53Å; H577-W660 AromaticContact CE1-CG 3.83Å; H577-W660 AromaticContact ND1-CD1 3.95Å; H577-W660 AromaticContact ND1-CG 3.91Å; H577-T732 HydrophobicContact CB-CG2 4.08Å; H577-M736 WeakPolarHBondContact NE2-CG 3.37Å; H577-V747 PolarHBondContact N-O 3.45Å; H577-I748 CarbonylContact O-C 3.5Å; H577-I748 WeakPolarHBondContact O-CA 3.41Å; H577-C749 PolarHBondContact O-N 2.79Å
578S98.3Very high96.3Very high0 Ų023.5 Ų23.50%012%0.117CC..EExtended strand (participates in β ladder)trans-95.9139.5177.1165.20000112.1L580 W660 N661 V662 C749S578-L580 WeakPolarHBondContact OG-CB 3.41Å; S578-L580 WeakPolarHBondContact OG-CG 3.21Å; S578-L580 PolarHBondContact OG-N 2.83Å; S578-L580 VanDerWaalsContact OG-N 3.15Å; S578-W660 PolarHBondContact N-O 3.49Å; S578-N661 VanDerWaalsContact CB-OD1 3.27Å; S578-N661 WeakPolarHBondContact CB-OD1 3.42Å; S578-N661 WeakPolarHBondContact O-CA 3.28Å; S578-N661 PolarHBondContact O-OD1 3.09Å; S578-N661 VanDerWaalsContact O-OD1 3.14Å; S578-N661 PolarHBondContact OG-OD1 3.12Å; S578-V662 PolarHBondContact O-N 3.11Å; S578-C749 CarbonylContact C-O 3.47Å; S578-C749 WeakPolarHBondContact CA-O 3.44Å
579F97.7Very high96.5Very high0 Ų022.1 Ų22.10%011%0.107CC..  trans-108.121.8170.4-62.4-67.6000114.3V662 V664 T732 I748 C749 C750 R756 A760 Y820F579-V662 VanDerWaalsContact CA-O 3.29Å; F579-V662 WeakPolarHBondContact CA-O 3.33Å; F579-V662 WeakPolarHBondContact CD1-O 3.46Å; F579-V664 HydrophobicContact CB-CB 4.48Å; F579-V664 HydrophobicContact CD1-CB 4.34Å; F579-V664 HydrophobicContact CD1-CG2 3.69Å; F579-V664 HydrophobicContact CE1-CG2 4.32Å; F579-V664 PolarHBondContact O-N 2.99Å; F579-T732 HydrophobicContact CE1-CG2 4.12Å; F579-T732 HydrophobicContact CZ-CG2 3.82Å; F579-I748 HydrophobicContact CD2-CG2 3.96Å; F579-I748 HydrophobicContact CE2-CG2 3.37Å; F579-I748 HydrophobicContact CZ-CG2 4.37Å; F579-C749 PolarHBondContact N-O 2.83Å; F579-C750 HydrophobicContact CB-CB 4.08Å; F579-R756 HydrophobicContact CB-CB 4.22Å; F579-R756 PolarHBondContact O-NH1 3.01Å; F579-A760 HydrophobicContact CD2-CB 4.4Å; F579-A760 HydrophobicContact CE2-CB 3.28Å; F579-A760 HydrophobicContact CZ-CB 3.4Å; F579-Y820 HydrophobicContact CD1-CE2 4.36Å; F579-Y820 AromaticContact CE1-CE2 3.74Å; F579-Y820 HydrophobicContact CE1-CE2 3.74Å; F579-Y820 HydrophobicContact CE2-CE2 4.46Å; F579-Y820 AromaticContact CZ-CE2 3.8Å; F579-Y820 HydrophobicContact CZ-CE2 3.8Å; F579-Y820 WeakPolarHBondContact CZ-OH 3.37Å
580L97.2Very high96.7Very high0 Ų017 Ų170%08%0.084CC..  trans-72.6141.9176.8-65.1171.7000111.3A317 S578 E586 M589 L590 L593 N661 G663 K751A317-L580 HydrophobicContact CB-CD1 3.84Å; A317-L580 HydrophobicContact CB-CD2 4.27Å; A317-L580 HydrophobicContact CB-CG 4.47Å; S578-L580 WeakPolarHBondContact OG-CB 3.41Å; S578-L580 WeakPolarHBondContact OG-CG 3.21Å; S578-L580 PolarHBondContact OG-N 2.83Å; S578-L580 VanDerWaalsContact OG-N 3.15Å; L580-E586 WeakPolarHBondContact CA-OE2 3.33Å; L580-E586 HydrophobicContact CB-CB 4.23Å; L580-E586 HydrophobicContact CD2-CB 4.1Å; L580-E586 HydrophobicContact CD2-CG 3.98Å; L580-M589 HydrophobicContact CD1-CB 3.62Å; L580-M589 HydrophobicContact CD2-CB 4.36Å; L580-M589 HydrophobicContact CD2-SD 4.01Å; L580-L590 HydrophobicContact CB-CD1 4.01Å; L580-L590 HydrophobicContact CB-CD2 3.95Å; L580-L590 HydrophobicContact CB-CG 3.71Å; L580-L590 HydrophobicContact CD1-CD2 3.93Å; L580-L590 HydrophobicContact CD1-CG 3.83Å; L580-L590 HydrophobicContact CG-CG 4.46Å; L580-L593 HydrophobicContact CD1-CD1 3.68Å; L580-N661 PolarHBondContact O-ND2 2.81Å; L580-N661 VanDerWaalsContact O-ND2 3.12Å; L580-N661 PolarHBondContact O-OD1 2.89Å; L580-G663 VanDerWaalsContact O-CA 3.24Å; L580-G663 WeakPolarHBondContact O-CA 3.22Å; L580-K751 HydrophobicContact CD2-CB 4.06Å
581S96.3Very high96.9Very high0 Ų017.3 Ų17.30%08%0.084CC..  trans-77.2151.3170.162.20000111.8F583 E586 R587 D667S581-F583 PolarHBondContact O-N 2.94Å; S581-E586 PolarHBondContact N-OE2 3.47Å; S581-E586 CarbonylContact O-C 3.5Å; S581-E586 VanDerWaalsContact O-C 3.29Å; S581-E586 VanDerWaalsContact O-CB 3.26Å; S581-E586 WeakPolarHBondContact O-CB 3.49Å; S581-E586 WeakPolarHBondContact OG-CB 3.06Å; S581-E586 PolarHBondContact OG-OE2 3.49Å; S581-R587 PolarHBondContact O-N 3.48Å; S581-D667 VanDerWaalsContact OG-CB 3.27Å; S581-D667 WeakPolarHBondContact OG-CB 3.32Å
582C95.9Very high97Very high0 Ų017 Ų170%08%0.081CC..SBendtrans-77.527.8172.7-63.30000113.5A671 E676C582-A671 HydrophobicContact CB-CB 4.07Å; C582-E676 WeakPolarHBondContact CB-O 3.44Å
583F94.4Very high97Very high36 Ų3617 Ų1716%0.1588%0.08CC..SBendtrans-127.8145.2-174.9-151.4-126.6000112.6S581 S585 E586 R587 D667 L670 A671 F674 E676S581-F583 PolarHBondContact O-N 2.94Å; F583-S585 PolarHBondContact O-N 3.09Å; F583-E586 PolarHBondContact O-N 3.35Å; F583-R587 PolarHBondContact O-N 2.65Å; F583-D667 HydrophobicContact CB-CB 4.26Å; F583-D667 WeakPolarHBondContact CB-O 3.03Å; F583-L670 HydrophobicContact CD1-CB 3.81Å; F583-L670 HydrophobicContact CD1-CD1 4.14Å; F583-L670 HydrophobicContact CE1-CB 3.82Å; F583-L670 HydrophobicContact CE1-CD1 3.89Å; F583-L670 HydrophobicContact CG-CB 4.34Å; F583-L670 HydrophobicContact CZ-CB 4.32Å; F583-A671 HydrophobicContact CB-CB 4.09Å; F583-A671 HydrophobicContact CD2-CB 4.44Å; F583-F674 HydrophobicContact CE2-CB 4.46Å; F583-F674 AromaticContact CE2-CD2 3.81Å; F583-F674 HydrophobicContact CE2-CD2 3.81Å; F583-F674 HydrophobicContact CE2-CG 4.47Å; F583-F674 AromaticContact CZ-CD2 3.69Å; F583-F674 HydrophobicContact CZ-CD2 3.69Å; F583-F674 AromaticContact CZ-CE2 3.98Å; F583-F674 HydrophobicContact CZ-CE2 3.98Å; F583-E676 HydrophobicContact CD2-CB 4.48Å; F583-E676 HydrophobicContact CD2-CG 4.43Å
584L92.3Very high96.9Very high103 Ų10318.4 Ų18.454%0.5399%0.088SC..Hα-helixtrans46.8-135.3174.7-59.2171.7000112.3E586 R587 Y588L584-E586 PolarHBondContact O-N 3.38Å; L584-E586 VanDerWaalsContact O-N 3.16Å; L584-R587 WeakPolarHBondContact O-CB 3.31Å; L584-R587 PolarHBondContact O-N 3.27Å; L584-R587 VanDerWaalsContact O-N 3.07Å; L584-Y588 WeakPolarHBondContact O-CD2 3.37Å
585S94Very high96.9Very high38 Ų3819.9 Ų19.927%0.26610%0.095SC..Hα-helixtrans-55.6-32.5-178.964.70000114.2F583 R587 Y588 M589F583-S585 PolarHBondContact O-N 3.09Å; S585-R587 VanDerWaalsContact C-N 3.33Å; S585-Y588 PolarHBondContact O-N 2.88Å; S585-M589 WeakPolarHBondContact O-CG 3.48Å; S585-M589 PolarHBondContact O-N 2.94Å; S585-M589 VanDerWaalsContact O-N 3.15Å
586E95.9Very high96.8Very high4 Ų419.8 Ų19.82%0.0199%0.094CC..Hα-helixtrans-73.6-27.3-178.9-67.4-161176.200111.8L580 S581 F583 L584 Y588 M589 L590 K751 R756L580-E586 WeakPolarHBondContact CA-OE2 3.33Å; L580-E586 HydrophobicContact CB-CB 4.23Å; L580-E586 HydrophobicContact CD2-CB 4.1Å; L580-E586 HydrophobicContact CD2-CG 3.98Å; S581-E586 PolarHBondContact N-OE2 3.47Å; S581-E586 CarbonylContact O-C 3.5Å; S581-E586 VanDerWaalsContact O-C 3.29Å; S581-E586 VanDerWaalsContact O-CB 3.26Å; S581-E586 WeakPolarHBondContact O-CB 3.49Å; S581-E586 WeakPolarHBondContact OG-CB 3.06Å; S581-E586 PolarHBondContact OG-OE2 3.49Å; F583-E586 PolarHBondContact O-N 3.35Å; L584-E586 PolarHBondContact O-N 3.38Å; L584-E586 VanDerWaalsContact O-N 3.16Å; E586-Y588 VanDerWaalsContact C-N 3.35Å; E586-M589 HydrophobicContact CG-SD 4.43Å; E586-M589 WeakPolarHBondContact O-CB 3.35Å; E586-M589 PolarHBondContact O-N 2.89Å; E586-L590 PolarHBondContact O-N 3.49Å; E586-K751 HydrophobicContact CG-CD 4.21Å; E586-K751 WeakPolarHBondContact OE1-CB 3.37Å; E586-K751 WeakPolarHBondContact OE1-CD 3.37Å; E586-R756 IonicContact OE1-CZ 2.71Å; E586-R756 IonicContact OE1-NH1 3.59Å; E586-R756 PolarHBondContact OE1-NH1 3.23Å; E586-R756 IonicContact OE1-NH2 3.07Å; E586-R756 PolarHBondContact OE1-NH2 3.15Å; E586-R756 IonicContact OE2-CZ 3.29Å; E586-R756 IonicContact OE2-NH1 3.62Å; E586-R756 PolarHBondContact OE2-NH1 2.89Å; E586-R756 IonicContact OE2-NH2 3.19Å
587R95.7Very high96.7Very high65 Ų6519.7 Ų19.725%0.2459%0.094CC..Hα-helixtrans-61.6-43.7170.4-174.9-176.3170.594.46.4111.4S581 F583 L584 S585 M589 L590 E591 E676 L679S581-R587 PolarHBondContact O-N 3.48Å; F583-R587 PolarHBondContact O-N 2.65Å; L584-R587 WeakPolarHBondContact O-CB 3.31Å; L584-R587 PolarHBondContact O-N 3.27Å; L584-R587 VanDerWaalsContact O-N 3.07Å; S585-R587 VanDerWaalsContact C-N 3.33Å; R587-M589 VanDerWaalsContact C-N 3.32Å; R587-M589 PolarHBondContact O-N 2.88Å; R587-L590 WeakPolarHBondContact O-CA 3.46Å; R587-L590 VanDerWaalsContact O-CB 3.3Å; R587-L590 WeakPolarHBondContact O-CB 3.39Å; R587-L590 PolarHBondContact O-N 2.9Å; R587-L590 VanDerWaalsContact O-N 3.07Å; R587-E591 IonicContact NE-OE1 2.85Å; R587-E591 PolarHBondContact O-N 3.11Å; R587-E676 IonicContact CZ-OE2 2.82Å; R587-E676 IonicContact NH1-OE2 3.76Å; R587-E676 PolarHBondContact NH1-OE2 2.81Å; R587-E676 VanDerWaalsContact NH1-OE2 3.15Å; R587-L679 HydrophobicContact CG-CD2 4.14Å
588Y96.9Very high96.6Very high81 Ų8121.7 Ų21.732%0.31811%0.108SC..Hα-helixtrans-68.9-32.6178.7-52.7-44.4000112.3Y325 G328 G329 L584 S585 E586 L590 E591 D592Y325-Y588 VanDerWaalsContact CB-CD2 3.47Å; Y325-Y588 VanDerWaalsContact CD1-CB 3.48Å; Y325-Y588 HydrophobicContact CD1-CD2 4.33Å; Y325-Y588 HydrophobicContact CD1-CG 4.37Å; Y325-Y588 HydrophobicContact CG-CD2 4.15Å; G328-Y588 VanDerWaalsContact CA-CD1 3.46Å; G329-Y588 WeakPolarHBondContact CA-O 3.3Å; L584-Y588 WeakPolarHBondContact O-CD2 3.37Å; S585-Y588 PolarHBondContact O-N 2.88Å; E586-Y588 VanDerWaalsContact C-N 3.35Å; Y588-L590 VanDerWaalsContact C-N 3.31Å; Y588-E591 WeakPolarHBondContact O-CB 3.47Å; Y588-E591 PolarHBondContact O-N 3.19Å; Y588-D592 PolarHBondContact O-N 3.13Å
589M97.9Very high96.4Very high1 Ų121.7 Ų21.71%0.00511%0.108CC..Hα-helixtrans-64.9-35.6168.9-60.9175.3-152.500111.7A317 T319 Y321 Y325 L580 S585 E586 R587 D592 L593 K751A317-M589 HydrophobicContact CB-CB 4.21Å; A317-M589 HydrophobicContact CB-SD 4.43Å; T319-M589 HydrophobicContact CG2-CG 3.91Å; T319-M589 HydrophobicContact CG2-SD 4.3Å; Y321-M589 HydrophobicContact CE1-CE 4.5Å; Y321-M589 HydrophobicContact CE1-SD 4.46Å; Y325-M589 HydrophobicContact CE1-CE 4.4Å; Y325-M589 HydrophobicContact CE1-CG 3.7Å; Y325-M589 HydrophobicContact CE2-CE 3.99Å; Y325-M589 WeakPolarHBondContact OH-CE 3.38Å; Y325-M589 WeakPolarHBondContact OH-CG 3.36Å; L580-M589 HydrophobicContact CD1-CB 3.62Å; L580-M589 HydrophobicContact CD2-CB 4.36Å; L580-M589 HydrophobicContact CD2-SD 4.01Å; S585-M589 WeakPolarHBondContact O-CG 3.48Å; S585-M589 PolarHBondContact O-N 2.94Å; S585-M589 VanDerWaalsContact O-N 3.15Å; E586-M589 HydrophobicContact CG-SD 4.43Å; E586-M589 WeakPolarHBondContact O-CB 3.35Å; E586-M589 PolarHBondContact O-N 2.89Å; R587-M589 VanDerWaalsContact C-N 3.32Å; R587-M589 PolarHBondContact O-N 2.88Å; M589-D592 WeakPolarHBondContact O-CB 3.34Å; M589-D592 PolarHBondContact O-N 3.42Å; M589-L593 WeakPolarHBondContact O-CG 3.42Å; M589-L593 PolarHBondContact O-N 3.37Å; M589-L593 VanDerWaalsContact O-N 3.1Å; M589-K751 HydrophobicContact CE-CD 4.06Å; M589-K751 HydrophobicContact CE-CG 4.05Å; M589-K751 HydrophobicContact SD-CB 4.45Å; M589-K751 HydrophobicContact SD-CG 4Å
590L97.6Very high96.3Very high0 Ų021.8 Ų21.80%011%0.109CC..Hα-helixtrans-66.5-40.7173.9-78.9168.5000112.2L580 E586 R587 Y588 D592 L593 I594 N661 L679 I683L580-L590 HydrophobicContact CB-CD1 4.01Å; L580-L590 HydrophobicContact CB-CD2 3.95Å; L580-L590 HydrophobicContact CB-CG 3.71Å; L580-L590 HydrophobicContact CD1-CD2 3.93Å; L580-L590 HydrophobicContact CD1-CG 3.83Å; L580-L590 HydrophobicContact CG-CG 4.46Å; E586-L590 PolarHBondContact O-N 3.49Å; R587-L590 WeakPolarHBondContact O-CA 3.46Å; R587-L590 VanDerWaalsContact O-CB 3.3Å; R587-L590 WeakPolarHBondContact O-CB 3.39Å; R587-L590 PolarHBondContact O-N 2.9Å; R587-L590 VanDerWaalsContact O-N 3.07Å; Y588-L590 VanDerWaalsContact C-N 3.31Å; L590-D592 PolarHBondContact O-N 3.42Å; L590-L593 HydrophobicContact CD2-CD1 4.34Å; L590-L593 PolarHBondContact O-N 3.21Å; L590-L593 VanDerWaalsContact O-N 3.15Å; L590-I594 VanDerWaalsContact O-CG1 3.24Å; L590-I594 WeakPolarHBondContact O-CG1 3.32Å; L590-I594 PolarHBondContact O-N 2.94Å; L590-N661 HydrophobicContact CD2-CB 4.2Å; L590-N661 VanDerWaalsContact CD2-OD1 3.31Å; L590-N661 WeakPolarHBondContact CD2-OD1 3.45Å; L590-L679 HydrophobicContact CB-CD2 4.47Å; L590-I683 HydrophobicContact CD2-CD1 4.2Å
591E97.8Very high96.3Very high17 Ų1724.6 Ų24.68%0.07912%0.119CC..Hα-helixtrans-56.5-41173.4-70.2172.1-163.700111.7G329 R331 G332 R587 Y588 E595G329-E591 WeakPolarHBondContact CA-OE2 3.38Å; G329-E591 PolarHBondContact N-OE2 3.18Å; R331-E591 HydrophobicContact CB-CB 3.9Å; R331-E591 HydrophobicContact CB-CG 4.02Å; G332-E591 PolarHBondContact N-OE2 3.34Å; G332-E591 VanDerWaalsContact N-OE2 3.11Å; R587-E591 IonicContact NE-OE1 2.85Å; R587-E591 PolarHBondContact O-N 3.11Å; Y588-E591 WeakPolarHBondContact O-CB 3.47Å; Y588-E591 PolarHBondContact O-N 3.19Å; E591-E595 PolarHBondContact O-N 2.54Å
592D98.3Very high96.3Very high0 Ų027.8 Ų27.80%014%0.141CC..Hα-helixtrans-63.3-45.8174.6-68.5-7.5000111.9F318 T319 G329 L330 R532 V536 Y588 M589 L590 I594 E595 M596F318-D592 WeakPolarHBondContact O-CB 3.48Å; T319-D592 WeakPolarHBondContact CA-OD2 3.27Å; T319-D592 WeakPolarHBondContact CB-OD2 3.27Å; T319-D592 PolarHBondContact OG1-OD2 3.5Å; G329-D592 WeakPolarHBondContact CA-OD1 3.48Å; L330-D592 HydrophobicContact CD1-CB 4.45Å; L330-D592 WeakPolarHBondContact CG-OD1 2.92Å; L330-D592 PolarHBondContact N-OD1 3.42Å; R532-D592 IonicContact CZ-OD1 2.73Å; R532-D592 IonicContact CZ-OD2 3.88Å; R532-D592 VanDerWaalsContact CZ-OD2 3.26Å; R532-D592 IonicContact NE-OD1 2.74Å; R532-D592 PolarHBondContact NE-OD1 2.97Å; R532-D592 IonicContact NE-OD2 3.56Å; R532-D592 PolarHBondContact NE-OD2 3.01Å; R532-D592 IonicContact NH2-OD1 2.71Å; R532-D592 IonicContact NH2-OD2 2.91Å; R532-D592 PolarHBondContact NH2-OD2 3.33Å; V536-D592 HydrophobicContact CG1-CB 4.15Å; V536-D592 HydrophobicContact CG2-CB 4.35Å; Y588-D592 PolarHBondContact O-N 3.13Å; M589-D592 WeakPolarHBondContact O-CB 3.34Å; M589-D592 PolarHBondContact O-N 3.42Å; L590-D592 PolarHBondContact O-N 3.42Å; D592-I594 PolarHBondContact O-N 3.36Å; D592-E595 PolarHBondContact O-N 3.27Å; D592-M596 WeakPolarHBondContact O-CG 3.48Å; D592-M596 PolarHBondContact O-N 2.76Å
593L98.2Very high96.2Very high0 Ų032.6 Ų32.60%016%0.16CC..Hα-helixtrans-62.3-41.8178.2-72-178.7000112.7F318 L576 L580 M589 L590 M596 A597 L659F318-L593 HydrophobicContact CB-CD2 3.8Å; F318-L593 HydrophobicContact CD2-CD2 3.53Å; F318-L593 HydrophobicContact CE2-CD2 4.35Å; F318-L593 HydrophobicContact CG-CD2 3.87Å; L576-L593 HydrophobicContact CD2-CD2 4.32Å; L580-L593 HydrophobicContact CD1-CD1 3.68Å; M589-L593 WeakPolarHBondContact O-CG 3.42Å; M589-L593 PolarHBondContact O-N 3.37Å; M589-L593 VanDerWaalsContact O-N 3.1Å; L590-L593 HydrophobicContact CD2-CD1 4.34Å; L590-L593 PolarHBondContact O-N 3.21Å; L590-L593 VanDerWaalsContact O-N 3.15Å; L593-M596 PolarHBondContact O-N 2.8Å; L593-A597 WeakPolarHBondContact O-CB 3.25Å; L593-A597 PolarHBondContact O-N 3.1Å; L593-L659 HydrophobicContact CB-CD1 4.38Å; L593-L659 HydrophobicContact CB-CD2 3.95Å; L593-L659 HydrophobicContact CD1-CD1 4.39Å
594I97.7Very high96.2Very high33 Ų3331 Ų3117%0.16915%0.153CC..Hα-helixtrans-60.1-49.6178.5-69.1162.8000109.9L590 D592 M596 A597 S598 L659 L679 I683L590-I594 VanDerWaalsContact O-CG1 3.24Å; L590-I594 WeakPolarHBondContact O-CG1 3.32Å; L590-I594 PolarHBondContact O-N 2.94Å; D592-I594 PolarHBondContact O-N 3.36Å; I594-M596 PolarHBondContact O-N 3.1Å; I594-A597 PolarHBondContact O-N 3.35Å; I594-S598 WeakPolarHBondContact O-CB 3.24Å; I594-S598 PolarHBondContact O-N 2.97Å; I594-S598 VanDerWaalsContact O-N 3.09Å; I594-L659 HydrophobicContact CG1-CD2 3.84Å; I594-L679 HydrophobicContact CD1-CD1 3.95Å; I594-I683 HydrophobicContact CD1-CD1 3.97Å; I594-I683 HydrophobicContact CD1-CG1 4.02Å; I594-I683 HydrophobicContact CG1-CD1 4.23Å; I594-I683 HydrophobicContact CG1-CG1 4.17Å
595E96.6Very high96.4Very high31 Ų3129.6 Ų29.615%0.14514%0.142CC..Hα-helixtrans-62.9-41.7178.8-77.6-59142.500111.9L330 R331 K352 Y533 E591 D592 S598 L599L330-E595 HydrophobicContact CB-CB 4.04Å; L330-E595 HydrophobicContact CB-CG 3.8Å; L330-E595 HydrophobicContact CD1-CB 3.93Å; R331-E595 HydrophobicContact CB-CG 4.41Å; K352-E595 IonicContact NZ-OE2 3.13Å; K352-E595 PolarHBondContact NZ-OE2 2.74Å; Y533-E595 PolarHBondContact OH-OE2 2.9Å; E591-E595 PolarHBondContact O-N 2.54Å; D592-E595 PolarHBondContact O-N 3.27Å; E595-S598 PolarHBondContact O-N 2.97Å; E595-L599 VanDerWaalsContact O-CB 3.32Å; E595-L599 WeakPolarHBondContact O-CB 3.29Å; E595-L599 PolarHBondContact O-N 2.77Å
596M96.2Very high96.6Very high1 Ų127.8 Ų27.81%0.00513%0.13CC..Hα-helixtrans-68.7-42.4178.7-72-47.790.200113.5L330 Y533 V536 L537 A540 D592 L593 I594 S598 L599 L600L330-M596 HydrophobicContact CD1-CE 3.36Å; Y533-M596 HydrophobicContact CD1-CE 3.54Å; Y533-M596 HydrophobicContact CE1-CE 3.52Å; V536-M596 HydrophobicContact CB-CG 3.99Å; V536-M596 HydrophobicContact CB-SD 4Å; V536-M596 HydrophobicContact CG1-CG 3.23Å; V536-M596 HydrophobicContact CG1-SD 3.93Å; L537-M596 HydrophobicContact CB-SD 4.08Å; A540-M596 HydrophobicContact CB-CB 4.25Å; A540-M596 HydrophobicContact CB-CG 4.29Å; D592-M596 WeakPolarHBondContact O-CG 3.48Å; D592-M596 PolarHBondContact O-N 2.76Å; L593-M596 PolarHBondContact O-N 2.8Å; I594-M596 PolarHBondContact O-N 3.1Å; M596-S598 PolarHBondContact O-N 3.02Å; M596-L599 HydrophobicContact CE-CD1 4.29Å; M596-L599 PolarHBondContact O-N 3.2Å; M596-L600 WeakPolarHBondContact O-CB 3.28Å; M596-L600 VanDerWaalsContact O-CG 3.25Å; M596-L600 WeakPolarHBondContact O-CG 3.28Å; M596-L600 PolarHBondContact O-N 2.86Å
597A97.7Very high96.6Very high3 Ų331.5 Ų31.53%0.02514%0.144CC..Hα-helixtrans-60.5-38.217600000110.9L593 I594 R601 V657 L659L593-A597 WeakPolarHBondContact O-CB 3.25Å; L593-A597 PolarHBondContact O-N 3.1Å; I594-A597 PolarHBondContact O-N 3.35Å; A597-R601 WeakPolarHBondContact O-CB 3.29Å; A597-R601 PolarHBondContact O-N 2.9Å; A597-R601 PolarHBondContact O-NH2 2.71Å; A597-V657 HydrophobicContact CB-CG1 4.13Å; A597-L659 HydrophobicContact CB-CB 4.02Å
598S96.3Very high96.5Very high42 Ų4228.5 Ų28.529%0.29413%0.132SC..Hα-helixtrans-66.2-45.8174.3-167.30000112.8I594 E595 M596 R601 S602I594-S598 WeakPolarHBondContact O-CB 3.24Å; I594-S598 PolarHBondContact O-N 2.97Å; I594-S598 VanDerWaalsContact O-N 3.09Å; E595-S598 PolarHBondContact O-N 2.97Å; M596-S598 PolarHBondContact O-N 3.02Å; S598-R601 PolarHBondContact O-N 3.36Å; S598-S602 WeakPolarHBondContact O-CB 3.49Å; S598-S602 PolarHBondContact O-N 2.74Å; S598-S602 VanDerWaalsContact O-N 3.07Å; S598-S602 PolarHBondContact O-OG 2.84Å
599L94.5Very high96.2Very high0 Ų027.3 Ų27.30%013%0.134CC..Hα-helixtrans-65-47.1-179.5-173.7156.8000111.5Y533 L537 E595 M596 R601 S602 R603 L626 I629Y533-L599 HydrophobicContact CD1-CD1 4.08Å; Y533-L599 HydrophobicContact CE1-CD1 3.91Å; L537-L599 HydrophobicContact CD1-CD2 3.61Å; E595-L599 VanDerWaalsContact O-CB 3.32Å; E595-L599 WeakPolarHBondContact O-CB 3.29Å; E595-L599 PolarHBondContact O-N 2.77Å; M596-L599 HydrophobicContact CE-CD1 4.29Å; M596-L599 PolarHBondContact O-N 3.2Å; L599-R601 VanDerWaalsContact C-N 3.27Å; L599-R601 PolarHBondContact O-N 3.37Å; L599-S602 PolarHBondContact O-N 3.26Å; L599-R603 HydrophobicContact CD2-CB 4.42Å; L599-R603 HydrophobicContact CG-CB 4.35Å; L599-R603 HydrophobicContact CG-CG 4.48Å; L599-R603 WeakPolarHBondContact O-CA 3.41Å; L599-R603 WeakPolarHBondContact O-CB 3.47Å; L599-R603 PolarHBondContact O-N 2.95Å; L599-L626 HydrophobicContact CD1-CD2 3.97Å; L599-I629 HydrophobicContact CD2-CD1 3.76Å
600L95.9Very high95.8Very high3 Ų331.2 Ų31.22%0.01615%0.148CC..Hα-helixtrans-56.7-41.3177.4-71.7167.3000112A540 L541 I544 M596 C604 V657A540-L600 HydrophobicContact CB-CD1 3.94Å; L541-L600 HydrophobicContact CD2-CD2 3.63Å; L541-L600 HydrophobicContact CG-CD2 4.14Å; I544-L600 HydrophobicContact CG1-CD1 3.92Å; M596-L600 WeakPolarHBondContact O-CB 3.28Å; M596-L600 VanDerWaalsContact O-CG 3.25Å; M596-L600 WeakPolarHBondContact O-CG 3.28Å; M596-L600 PolarHBondContact O-N 2.86Å; L600-C604 WeakPolarHBondContact O-CB 3.3Å; L600-C604 PolarHBondContact O-N 3.2Å; L600-V657 HydrophobicContact CB-CB 4.5Å; L600-V657 HydrophobicContact CB-CG2 3.93Å; L600-V657 HydrophobicContact CD1-CG2 4.02Å
601R96.6Very high95Very high58 Ų5832.2 Ų32.222%0.21915%0.153CC..Hα-helixtrans-71.9-37.2179.9-165.7-171.1-29.697.15.5113.7A597 S598 L599A597-R601 WeakPolarHBondContact O-CB 3.29Å; A597-R601 PolarHBondContact O-N 2.9Å; A597-R601 PolarHBondContact O-NH2 2.71Å; S598-R601 PolarHBondContact O-N 3.36Å; L599-R601 VanDerWaalsContact C-N 3.27Å; L599-R601 PolarHBondContact O-N 3.37Å
602S95.1Very high93.7Very high67 Ų6738.6 Ų38.647%0.46918%0.181SC..Hα-helixtrans-100.6-23.6-168.759.10000114.4S598 L599S598-S602 WeakPolarHBondContact O-CB 3.49Å; S598-S602 PolarHBondContact O-N 2.74Å; S598-S602 VanDerWaalsContact O-N 3.07Å; S598-S602 PolarHBondContact O-OG 2.84Å; L599-S602 PolarHBondContact O-N 3.26Å
603R94.2Very high91.8Very high102 Ų10244.2 Ų44.239%0.38522%0.22SC..Hα-helixtrans-124.2-12-170.9-56.7-58.5-174.7161.2-5.7114L599 G627 I629L599-R603 HydrophobicContact CD2-CB 4.42Å; L599-R603 HydrophobicContact CG-CB 4.35Å; L599-R603 HydrophobicContact CG-CG 4.48Å; L599-R603 WeakPolarHBondContact O-CA 3.41Å; L599-R603 WeakPolarHBondContact O-CB 3.47Å; L599-R603 PolarHBondContact O-N 2.95Å; R603-G627 WeakPolarHBondContact CD-O 3.24Å; R603-G627 PolarHBondContact NH1-O 2.7Å; R603-I629 PolarHBondContact O-N 2.95Å
604C95.4Very high89.7Confident3 Ų350.6 Ų50.62%0.0226%0.259CS..EExtended strand (participates in β ladder)trans-100.8138.9176.1-57.80000111.5L600 F606 I629L600-C604 WeakPolarHBondContact O-CB 3.3Å; L600-C604 PolarHBondContact O-N 3.2Å; C604-F606 HydrophobicContact CB-CE2 3.89Å; C604-F606 HydrophobicContact CB-CZ 4.33Å; C604-I629 WeakPolarHBondContact CA-O 3.42Å; C604-I629 HydrophobicContact CB-CB 4.43Å
605K96.3Very high87.7Confident72 Ų7251.3 Ų51.331%0.31327%0.267SS..EExtended strand (participates in β ladder)trans-136.4149.8169.859.2176.2-170170.20111I629 K630 V631 W652 F653K605-I629 PolarHBondContact N-O 2.78Å; K605-K630 HydrophobicContact CG-CG 4.16Å; K605-K630 WeakPolarHBondContact O-CA 3.24Å; K605-V631 PolarHBondContact O-N 2.74Å; K605-W652 HydrophobicContact CB-CB 4.41Å; K605-W652 HydrophobicContact CB-CE3 3.95Å; K605-W652 HydrophobicContact CD-CB 4Å; K605-W652 HydrophobicContact CD-CD2 3.72Å; K605-W652 HydrophobicContact CD-CE3 3.8Å; K605-W652 HydrophobicContact CD-CG 3.81Å; K605-W652 HydrophobicContact CG-CD2 4Å; K605-W652 HydrophobicContact CG-CE3 3.51Å; K605-W652 HydrophobicContact CG-CG 4.46Å; K605-W652 HydrophobicContact CG-CZ3 4.06Å; K605-W652 WeakPolarHBondContact O-CZ3 3.31Å; K605-F653 WeakPolarHBondContact CA-O 3.24Å
606F97.2Very high86Confident1 Ų159 Ų590%0.00430%0.3CS..EExtended strand (participates in β ladder)trans-122.6145-170.9-62.3-101.4000110I544 V545 L548 C604 V631 L633 W652 F653 V655I544-F606 HydrophobicContact CG2-CZ 4.12Å; V545-F606 HydrophobicContact CG2-CE1 4.08Å; L548-F606 HydrophobicContact CD1-CD1 3.59Å; L548-F606 HydrophobicContact CD1-CE1 3.73Å; L548-F606 HydrophobicContact CD1-CG 4.11Å; L548-F606 HydrophobicContact CD1-CZ 4.35Å; C604-F606 HydrophobicContact CB-CE2 3.89Å; C604-F606 HydrophobicContact CB-CZ 4.33Å; F606-V631 CarbonylContact C-O 3.59Å; F606-V631 VanDerWaalsContact CA-O 3.22Å; F606-V631 WeakPolarHBondContact CA-O 3.38Å; F606-V631 HydrophobicContact CD1-CB 3.54Å; F606-V631 HydrophobicContact CD1-CG1 3.83Å; F606-V631 HydrophobicContact CD1-CG2 4.2Å; F606-V631 HydrophobicContact CE1-CB 3.65Å; F606-V631 HydrophobicContact CE1-CG1 3.87Å; F606-V631 HydrophobicContact CE1-CG2 3.82Å; F606-V631 HydrophobicContact CG-CB 4.29Å; F606-V631 HydrophobicContact CZ-CB 4.48Å; F606-V631 HydrophobicContact CZ-CG2 4.26Å; F606-L633 HydrophobicContact CD1-CD1 4.17Å; F606-L633 HydrophobicContact CD1-CG 4.48Å; F606-W652 VanDerWaalsContact C-CE3 3.44Å; F606-W652 CarbonylContact O-C 3.54Å; F606-W652 VanDerWaalsContact O-CA 3.28Å; F606-W652 WeakPolarHBondContact O-CA 3.19Å; F606-F653 HydrophobicContact CB-CD1 4.17Å; F606-F653 HydrophobicContact CB-CD2 4.22Å; F606-F653 HydrophobicContact CB-CE1 3.68Å; F606-F653 HydrophobicContact CB-CE2 3.75Å; F606-F653 HydrophobicContact CB-CG 4.42Å; F606-F653 HydrophobicContact CB-CZ 3.45Å; F606-F653 VanDerWaalsContact CB-CZ 3.45Å; F606-F653 HydrophobicContact CG-CE2 4.4Å; F606-F653 HydrophobicContact CG-CZ 4.4Å; F606-F653 PolarHBondContact N-O 3.39Å; F606-F653 WeakPolarHBondContact O-CD1 3.49Å; F606-F653 PolarHBondContact O-N 2.91Å; F606-V655 HydrophobicContact CD2-CB 4.32Å; F606-V655 HydrophobicContact CD2-CG2 3.36Å; F606-V655 HydrophobicContact CE1-CG2 4.48Å; F606-V655 HydrophobicContact CE2-CB 3.9Å; F606-V655 HydrophobicContact CE2-CG2 3.26Å; F606-V655 HydrophobicContact CG-CG2 4.07Å; F606-V655 HydrophobicContact CZ-CG2 3.88Å
607R95.6Very high84.6Confident81 Ų8161.4 Ų61.431%0.30632%0.317SS..EExtended strand (participates in β ladder)trans-135.5155.9170.768.4170.9174.8179.8-2.7110E623 V631 T632 L633 W652R607-E623 IonicContact NH2-OE2 2.79Å; R607-V631 PolarHBondContact N-O 3.48Å; R607-T632 HydrophobicContact CG-CG2 3.98Å; R607-T632 PolarHBondContact NE-OG1 2.86Å; R607-T632 PolarHBondContact NH2-OG1 3.37Å; R607-T632 WeakPolarHBondContact O-CA 3.23Å; R607-L633 PolarHBondContact O-N 3.25Å; R607-W652 HydrophobicContact CB-CD2 4.03Å; R607-W652 HydrophobicContact CB-CE3 3.79Å; R607-W652 HydrophobicContact CB-CH2 4.2Å; R607-W652 HydrophobicContact CB-CZ2 4.44Å; R607-W652 HydrophobicContact CB-CZ3 3.88Å; R607-W652 HydrophobicContact CG-CD2 4.48Å; R607-W652 HydrophobicContact CG-CE3 4.1Å; R607-W652 HydrophobicContact CG-CH2 3.6Å; R607-W652 HydrophobicContact CG-CZ2 4.03Å; R607-W652 HydrophobicContact CG-CZ3 3.65Å
608L94.6Very high83.5Confident2 Ų262.1 Ų62.11%0.0132%0.322CS..EExtended strand (participates in β ladder)trans-103.1146.3178.6-55.2-172.2000110.7L552 L633 V635 W640 L643 L647 F653L552-L608 HydrophobicContact CD1-CD2 3.77Å; L552-L608 HydrophobicContact CD2-CD1 3.98Å; L552-L608 HydrophobicContact CD2-CD2 4.26Å; L608-L633 WeakPolarHBondContact CA-O 3.41Å; L608-L633 HydrophobicContact CD2-CB 3.94Å; L608-L633 HydrophobicContact CD2-CD1 4.37Å; L608-V635 HydrophobicContact CB-CG2 3.83Å; L608-V635 HydrophobicContact CD1-CG2 4.05Å; L608-V635 HydrophobicContact CD2-CG2 4.18Å; L608-V635 HydrophobicContact CG-CG2 4.23Å; L608-W640 HydrophobicContact CB-CZ3 4.18Å; L608-L643 HydrophobicContact CD1-CD1 3.98Å; L608-L643 HydrophobicContact CD1-CD2 4.01Å; L608-L647 HydrophobicContact CD1-CB 4.21Å; L608-L647 HydrophobicContact CD1-CD1 4.01Å; L608-F653 HydrophobicContact CD2-CE1 3.9Å; L608-F653 HydrophobicContact CD2-CZ 4.22Å; L608-F653 HydrophobicContact CG-CE1 4.03Å
609V89.6Confident82.7Confident57 Ų5764 Ų6435%0.34533%0.334SS..EExtended strand (participates in β ladder)trans-134.9144.6172.6-67.40000110.9M611 T632 L633 P634 V635V609-M611 PolarHBondContact O-N 3.09Å; V609-T632 HydrophobicContact CB-CG2 4.16Å; V609-T632 HydrophobicContact CG1-CG2 3.45Å; V609-T632 VanDerWaalsContact CG1-CG2 3.45Å; V609-T632 HydrophobicContact CG2-CG2 3.6Å; V609-L633 PolarHBondContact N-O 3.22Å; V609-P634 WeakPolarHBondContact O-CA 3.38Å; V609-V635 PolarHBondContact O-N 2.72Å
610R89.7Confident82.2Confident82 Ų8264.8 Ų64.831%0.30934%0.34SS..EExtended strand (participates in β ladder)trans-68.9128.8177.6-166.1173.2-170.3143.413109.7S637 W640 D641R610-S637 PolarHBondContact NE-OG 2.69Å; R610-S637 PolarHBondContact NH2-O 3.47Å; R610-W640 HydrophobicContact CB-CD2 3.54Å; R610-W640 HydrophobicContact CB-CE3 3.71Å; R610-W640 HydrophobicContact CB-CG 3.97Å; R610-W640 HydrophobicContact CB-CH2 4.36Å; R610-W640 HydrophobicContact CB-CZ2 4.21Å; R610-W640 HydrophobicContact CB-CZ3 4.14Å; R610-W640 HydrophobicContact CG-CB 3.94Å; R610-W640 HydrophobicContact CG-CD2 3.82Å; R610-W640 HydrophobicContact CG-CE3 4.25Å; R610-W640 HydrophobicContact CG-CG 3.67Å; R610-D641 IonicContact CZ-OD1 3.21Å; R610-D641 IonicContact CZ-OD2 3.84Å; R610-D641 IonicContact NH1-OD1 2.92Å; R610-D641 PolarHBondContact NH1-OD1 3.4Å; R610-D641 IonicContact NH1-OD2 2.96Å; R610-D641 IonicContact NH2-OD1 2.61Å; R610-D641 PolarHBondContact NH2-OD1 2.58Å; R610-D641 IonicContact NH2-OD2 3.43Å; R610-D641 PolarHBondContact NH2-OD2 3.26Å
611M81.9Confident81.6Confident21 Ų2168.3 Ų68.310%0.10336%0.361CS..PPolyproline II helixtrans-84.5123.6172.2-172.7154.6161.400110.1L191 W553 V609 S615 S617 P634 V635 S637L191-M611 HydrophobicContact CD2-CE 4.25Å; W553-M611 HydrophobicContact CH2-CE 4Å; W553-M611 HydrophobicContact CH2-SD 3.41Å; W553-M611 WeakPolarHBondContact CH2-SD 3.35Å; W553-M611 HydrophobicContact CZ2-SD 3.54Å; W553-M611 VanDerWaalsContact CZ2-SD 3.54Å; V609-M611 PolarHBondContact O-N 3.09Å; M611-S615 WeakPolarHBondContact CE-O 3.31Å; M611-S615 WeakPolarHBondContact CE-OG 3.19Å; M611-S617 WeakPolarHBondContact CE-O 3.47Å; M611-P634 HydrophobicContact CB-CB 4.27Å; M611-P634 HydrophobicContact SD-CB 4.07Å; M611-V635 WeakPolarHBondContact CB-O 3.43Å; M611-V635 PolarHBondContact N-O 3.22Å; M611-S637 PolarHBondContact O-OG 2.94Å
612F70Confident81Confident151 Ų15167.2 Ų67.266%0.66236%0.361SS*.PPolyproline II helixtrans-82.5131.6175.5-60.1-78.8000110.3V614 S615F612-V614 PolarHBondContact O-N 3.1Å; F612-S615 PolarHBondContact O-N 3.16Å; F612-S615 VanDerWaalsContact O-N 3.12Å; F612-S615 PolarHBondContact O-OG 2.87Å; F612-S615 VanDerWaalsContact O-OG 3.11Å
613S59.2Low80.5Confident118 Ų11868.1 Ų68.183%0.82536%0.358SS*.THydrogen-bonded Turntrans-48.5-20.5-172.7155.50000116.4S615S613-S615 VanDerWaalsContact C-N 3.3Å; S613-S615 PolarHBondContact O-N 2.8Å
614V54Low80Confident135 Ų13564.5 Ų64.582%0.81835%0.352SS*.THydrogen-bonded Turntrans-71.6-23-177.8-156.10000112.7F612F612-V614 PolarHBondContact O-N 3.1Å
615S54.1Low79.6Confident47 Ų4765 Ų6533%0.32936%0.355SS..  trans-90.5124.2-178.856.30000112M611 F612 S613 S617M611-S615 WeakPolarHBondContact CE-O 3.31Å; M611-S615 WeakPolarHBondContact CE-OG 3.19Å; F612-S615 PolarHBondContact O-N 3.16Å; F612-S615 VanDerWaalsContact O-N 3.12Å; F612-S615 PolarHBondContact O-OG 2.87Å; F612-S615 VanDerWaalsContact O-OG 3.11Å; S613-S615 VanDerWaalsContact C-N 3.3Å; S613-S615 PolarHBondContact O-N 2.8Å; S615-S617 VanDerWaalsContact C-N 3.26Å; S615-S617 PolarHBondContact O-N 3.21Å
616K61.3Low79.2Confident192 Ų19262.1 Ų62.184%0.83534%0.343SS*.  trans-90.624.9170.6-64.6-170.4176.7-172.40112.9L191L191-K616 WeakPolarHBondContact CD1-O 2.89Å
617S66.9Low78.7Confident53 Ų5362.2 Ų62.237%0.37134%0.344SS..  trans-133.5117.1-175.256.50000110.7M611 S615 S619M611-S617 WeakPolarHBondContact CE-O 3.47Å; S615-S617 VanDerWaalsContact C-N 3.26Å; S615-S617 PolarHBondContact O-N 3.21Å; S617-S619 PolarHBondContact O-N 2.89Å
618C75Confident78.5Confident18 Ų1860.1 Ų60.112%0.12234%0.344CS..  trans-86.488.7166.6173.50000108.3L191 L192 W553 P634L191-C618 HydrophobicContact CD1-CB 4.45Å; L191-C618 HydrophobicContact CD2-CB 3.6Å; L191-C618 HydrophobicContact CG-CB 3.77Å; L192-C618 HydrophobicContact CD2-CB 3.92Å; L192-C618 WeakPolarHBondContact CD2-SG 3.45Å; W553-C618 HydrophobicContact CH2-CB 4.37Å; W553-C618 HydrophobicContact CZ2-CB 3.99Å; C618-P634 HydrophobicContact CB-CG 4.46Å; C618-P634 VanDerWaalsContact SG-CG 3.55Å
619S79Confident78.3Confident80 Ų8060.3 Ų60.356%0.55935%0.345SS*.  trans-114.5107.6179.6-64.50000109.8S617S617-S619 PolarHBondContact O-N 2.89Å
620P84.9Confident78.4Confident18 Ų1861.1 Ų61.112%0.11734%0.344CS..  trans-68.6153.2170.530.1-34.5000110.8L222 V545 L549 T632 L633L222-P620 HydrophobicContact CB-CG 4.46Å; L222-P620 HydrophobicContact CD1-CG 3.4Å; L222-P620 HydrophobicContact CD2-CG 3.22Å; L222-P620 HydrophobicContact CG-CG 3.82Å; V545-P620 HydrophobicContact CG1-CB 4.1Å; V545-P620 HydrophobicContact CG1-CG 3.88Å; L549-P620 HydrophobicContact CD1-CG 4.43Å; P620-T632 CarbonylContact C-O 3.46Å; P620-T632 WeakPolarHBondContact CA-O 3.34Å; P620-T632 WeakPolarHBondContact CB-O 3.35Å; P620-L633 HydrophobicContact CB-CD2 3.73Å
621V82.2Confident78.5Confident77 Ų7757.2 Ų57.247%0.46733%0.329SS..EExtended strand (participates in β ladder)trans-110.2120.6179.3-174.20000108.7E623 V631 T632V621-E623 HydrophobicContact CG1-CG 3.97Å; V621-V631 CarbonylContact O-C 3.45Å; V621-V631 WeakPolarHBondContact O-CA 3.22Å; V621-T632 PolarHBondContact N-O 3.35Å; V621-T632 PolarHBondContact O-N 3.13Å
622V84Confident78.9Confident35 Ų3556.6 Ų56.621%0.21233%0.326CS..EExtended strand (participates in β ladder)trans-106.2123.8177.1-177.30000108.7C224 L541 I629 V631C224-V622 HydrophobicContact CB-CG2 4.36Å; L541-V622 HydrophobicContact CD1-CG1 4.37Å; V622-I629 HydrophobicContact CG1-CG2 4.14Å; V622-V631 HydrophobicContact CG1-CG2 4.48Å; V622-V631 HydrophobicContact CG2-CG1 4.36Å; V622-V631 HydrophobicContact CG2-CG2 4.35Å
623E84.5Confident79.9Confident85 Ų8549.4 Ų49.440%0.39730%0.295SS..EExtended strand (participates in β ladder)trans-127.3153.6-178.3-55.5175.69900110.7R607 V621 K630R607-E623 IonicContact NH2-OE2 2.79Å; V621-E623 HydrophobicContact CG1-CG 3.97Å; E623-K630 HydrophobicContact CB-CB 4.27Å; E623-K630 PolarHBondContact N-O 3.25Å; E623-K630 PolarHBondContact O-N 3.28Å
624G84.8Confident81.4Confident26 Ų2644.3 Ų44.327%0.26826%0.259SS..EExtended strand (participates in β ladder)trans99.5-151.2173.600000114.6A226A226-G624 WeakPolarHBondContact CB-O 3.46Å
625D86Confident83.1Confident14 Ų1437.9 Ų37.98%0.07522%0.22CC..EExtended strand (participates in β ladder)trans-153.4-178.9-171.663.852.2000110.2F228 A355 R359 G627 A628 I629F228-D625 HydrophobicContact CB-CB 4.1Å; F228-D625 HydrophobicContact CD1-CB 3.93Å; F228-D625 HydrophobicContact CD2-CB 4.14Å; F228-D625 HydrophobicContact CE1-CB 4.38Å; F228-D625 VanDerWaalsContact CE2-OD2 3.25Å; F228-D625 WeakPolarHBondContact CE2-OD2 3.14Å; F228-D625 HydrophobicContact CG-CB 3.76Å; F228-D625 WeakPolarHBondContact CZ-OD2 3.47Å; A355-D625 HydrophobicContact CB-CB 4.24Å; A355-D625 VanDerWaalsContact CB-OD1 3.26Å; A355-D625 WeakPolarHBondContact CB-OD1 3.36Å; R359-D625 IonicContact CZ-OD1 3.43Å; R359-D625 IonicContact CZ-OD2 2.8Å; R359-D625 IonicContact NE-OD1 3.74Å; R359-D625 IonicContact NE-OD2 3.59Å; R359-D625 PolarHBondContact NE-OD2 3.13Å; R359-D625 IonicContact NH1-OD2 3.9Å; R359-D625 IonicContact NH2-OD1 3.08Å; R359-D625 PolarHBondContact NH2-OD1 3.47Å; R359-D625 IonicContact NH2-OD2 3.91Å; R359-D625 PolarHBondContact NH2-OD2 3.27Å; D625-G627 PolarHBondContact O-N 2.82Å; D625-G627 WeakPolarHBondContact OD1-CA 3.36Å; D625-G627 PolarHBondContact OD1-N 3.31Å; D625-A628 PolarHBondContact N-O 3.13Å; D625-A628 CarbonylContact O-C 3.59Å; D625-A628 PolarHBondContact O-N 3.23Å; D625-I629 WeakPolarHBondContact O-CG1 3.4Å
626L88.4Confident84.8Confident11 Ų1135.8 Ų35.86%0.05821%0.206CC..THydrogen-bonded Turntrans-54-23.8-178.1-67.7174.3000114.9L351 A355 L530 Y533 L537 L599L351-L626 HydrophobicContact CB-CD1 4.14Å; A355-L626 HydrophobicContact CB-CB 4.1Å; L530-L626 HydrophobicContact CD1-CD1 4.34Å; Y533-L626 HydrophobicContact CD1-CD2 4.02Å; Y533-L626 HydrophobicContact CG-CD1 4.27Å; Y533-L626 HydrophobicContact CG-CD2 4.35Å; L537-L626 HydrophobicContact CD2-CD2 3.82Å; L599-L626 HydrophobicContact CD1-CD2 3.97Å
627G87.2Confident86Confident4 Ų428.1 Ų28.14%0.04118%0.176CC..THydrogen-bonded Turntrans-79.2-28.4177.200000114.1K352 R603 D625K352-G627 WeakPolarHBondContact O-CA 3.43Å; R603-G627 WeakPolarHBondContact CD-O 3.24Å; R603-G627 PolarHBondContact NH1-O 2.7Å; D625-G627 PolarHBondContact O-N 2.82Å; D625-G627 WeakPolarHBondContact OD1-CA 3.36Å; D625-G627 PolarHBondContact OD1-N 3.31Å
628A91Very high87Confident37 Ų3730.7 Ų30.731%0.30618%0.182SC..EExtended strand (participates in β ladder)trans-166.5115.117600000111.2R359 D625R359-A628 VanDerWaalsContact NH2-N 3.16Å; R359-A628 PolarHBondContact NH2-O 2.99Å; D625-A628 PolarHBondContact N-O 3.13Å; D625-A628 CarbonylContact O-C 3.59Å; D625-A628 PolarHBondContact O-N 3.23Å
629I91.1Very high87.8Confident5 Ų531.3 Ų31.33%0.02618%0.182CC..EExtended strand (participates in β ladder)trans-107.9132.5-177.9-56.6168000108.5L537 L541 L599 R603 C604 K605 V622 D625 V631L537-I629 HydrophobicContact CD1-CD1 3.75Å; L537-I629 HydrophobicContact CD2-CD1 3.45Å; L537-I629 VanDerWaalsContact CD2-CD1 3.45Å; L537-I629 HydrophobicContact CG-CD1 4.17Å; L541-I629 HydrophobicContact CD1-CD1 4.48Å; L541-I629 HydrophobicContact CD1-CG2 4.12Å; L599-I629 HydrophobicContact CD2-CD1 3.76Å; R603-I629 PolarHBondContact O-N 2.95Å; C604-I629 WeakPolarHBondContact CA-O 3.42Å; C604-I629 HydrophobicContact CB-CB 4.43Å; K605-I629 PolarHBondContact N-O 2.78Å; V622-I629 HydrophobicContact CG1-CG2 4.14Å; D625-I629 WeakPolarHBondContact O-CG1 3.4Å; I629-V631 HydrophobicContact CG2-CG2 4.13Å
630K90.7Very high88.4Confident75 Ų7529 Ų2933%0.32616%0.161SC..EExtended strand (participates in β ladder)trans-120.5126.4-179.6-67.8-179.4-169.3173.70108.3K605 E623 W652K605-K630 HydrophobicContact CG-CG 4.16Å; K605-K630 WeakPolarHBondContact O-CA 3.24Å; E623-K630 HydrophobicContact CB-CB 4.27Å; E623-K630 PolarHBondContact N-O 3.25Å; E623-K630 PolarHBondContact O-N 3.28Å; K630-W652 HydrophobicContact CB-CH2 3.59Å; K630-W652 HydrophobicContact CB-CZ2 4.44Å; K630-W652 HydrophobicContact CB-CZ3 3.82Å; K630-W652 HydrophobicContact CD-CH2 4.05Å; K630-W652 HydrophobicContact CD-CZ2 4.08Å; K630-W652 HydrophobicContact CG-CH2 3.96Å; K630-W652 HydrophobicContact CG-CZ2 4.4Å; K630-W652 HydrophobicContact CG-CZ3 4.22Å
631V91.4Very high88.8Confident0 Ų032.7 Ų32.70%018%0.18CC..EExtended strand (participates in β ladder)trans-122.1127.9-179.9-175.10000109.6L541 V545 K605 F606 R607 V621 V622 I629 L633L541-V631 HydrophobicContact CD2-CG2 4.3Å; V545-V631 HydrophobicContact CG2-CG1 3.88Å; K605-V631 PolarHBondContact O-N 2.74Å; F606-V631 CarbonylContact C-O 3.59Å; F606-V631 VanDerWaalsContact CA-O 3.22Å; F606-V631 WeakPolarHBondContact CA-O 3.38Å; F606-V631 HydrophobicContact CD1-CB 3.54Å; F606-V631 HydrophobicContact CD1-CG1 3.83Å; F606-V631 HydrophobicContact CD1-CG2 4.2Å; F606-V631 HydrophobicContact CE1-CB 3.65Å; F606-V631 HydrophobicContact CE1-CG1 3.87Å; F606-V631 HydrophobicContact CE1-CG2 3.82Å; F606-V631 HydrophobicContact CG-CB 4.29Å; F606-V631 HydrophobicContact CZ-CB 4.48Å; F606-V631 HydrophobicContact CZ-CG2 4.26Å; R607-V631 PolarHBondContact N-O 3.48Å; V621-V631 CarbonylContact O-C 3.45Å; V621-V631 WeakPolarHBondContact O-CA 3.22Å; V622-V631 HydrophobicContact CG1-CG2 4.48Å; V622-V631 HydrophobicContact CG2-CG1 4.36Å; V622-V631 HydrophobicContact CG2-CG2 4.35Å; I629-V631 HydrophobicContact CG2-CG2 4.13Å; V631-L633 HydrophobicContact CG1-CD2 3.7Å; V631-L633 HydrophobicContact CG1-CG 4.37Å
632T90.3Very high89.3Confident7 Ų732.6 Ų32.64%0.04318%0.176CC..EExtended strand (participates in β ladder)trans-108.4124.9177.5-540000109R607 V609 P620 V621R607-T632 HydrophobicContact CG-CG2 3.98Å; R607-T632 PolarHBondContact NE-OG1 2.86Å; R607-T632 PolarHBondContact NH2-OG1 3.37Å; R607-T632 WeakPolarHBondContact O-CA 3.23Å; V609-T632 HydrophobicContact CB-CG2 4.16Å; V609-T632 HydrophobicContact CG1-CG2 3.45Å; V609-T632 VanDerWaalsContact CG1-CG2 3.45Å; V609-T632 HydrophobicContact CG2-CG2 3.6Å; P620-T632 CarbonylContact C-O 3.46Å; P620-T632 WeakPolarHBondContact CA-O 3.34Å; P620-T632 WeakPolarHBondContact CB-O 3.35Å; V621-T632 PolarHBondContact N-O 3.35Å; V621-T632 PolarHBondContact O-N 3.13Å
633L92.1Very high89.8Confident0 Ų031.2 Ų31.20%017%0.168CC..EExtended strand (participates in β ladder)trans-112.8128.5-176-56.1-178.5000111.2V545 L548 L549 L552 F606 R607 L608 V609 P620 V631V545-L633 HydrophobicContact CG1-CD2 3.52Å; V545-L633 HydrophobicContact CG2-CD2 4.33Å; L548-L633 HydrophobicContact CB-CD1 3.63Å; L548-L633 HydrophobicContact CD1-CD1 3.73Å; L548-L633 HydrophobicContact CG-CD1 4.35Å; L549-L633 HydrophobicContact CD2-CB 4.35Å; L549-L633 HydrophobicContact CD2-CD2 4.36Å; L552-L633 HydrophobicContact CD1-CB 4.01Å; L552-L633 HydrophobicContact CD1-CD1 4.15Å; F606-L633 HydrophobicContact CD1-CD1 4.17Å; F606-L633 HydrophobicContact CD1-CG 4.48Å; R607-L633 PolarHBondContact O-N 3.25Å; L608-L633 WeakPolarHBondContact CA-O 3.41Å; L608-L633 HydrophobicContact CD2-CB 3.94Å; L608-L633 HydrophobicContact CD2-CD1 4.37Å; V609-L633 PolarHBondContact N-O 3.22Å; P620-L633 HydrophobicContact CB-CD2 3.73Å; V631-L633 HydrophobicContact CG1-CD2 3.7Å; V631-L633 HydrophobicContact CG1-CG 4.37Å
634P89.5Confident90.2Very high12 Ų1228.6 Ų28.68%0.07816%0.158CC..EExtended strand (participates in β ladder)trans-75.5139.3174.131.2-35.5000111.7L549 W553 V609 M611 C618L549-P634 HydrophobicContact CD2-CG 4.45Å; W553-P634 PolarHBondContact NE1-O 3.24Å; V609-P634 WeakPolarHBondContact O-CA 3.38Å; M611-P634 HydrophobicContact CB-CB 4.27Å; M611-P634 HydrophobicContact SD-CB 4.07Å; C618-P634 HydrophobicContact CB-CG 4.46Å; C618-P634 VanDerWaalsContact SG-CG 3.55Å
635V91.1Very high90.7Very high0 Ų034.8 Ų34.80%018%0.18CC..EExtended strand (participates in β ladder)trans-116.5137.6176.3-173.80000109.5L552 L608 V609 M611 R639 W640 L643L552-V635 HydrophobicContact CD1-CG2 4.17Å; L552-V635 HydrophobicContact CD2-CG1 4.44Å; L552-V635 HydrophobicContact CD2-CG2 3.94Å; L608-V635 HydrophobicContact CB-CG2 3.83Å; L608-V635 HydrophobicContact CD1-CG2 4.05Å; L608-V635 HydrophobicContact CD2-CG2 4.18Å; L608-V635 HydrophobicContact CG-CG2 4.23Å; V609-V635 PolarHBondContact O-N 2.72Å; M611-V635 WeakPolarHBondContact CB-O 3.43Å; M611-V635 PolarHBondContact N-O 3.22Å; V635-R639 HydrophobicContact CG1-CB 4.07Å; V635-W640 HydrophobicContact CB-CE3 4.04Å; V635-W640 HydrophobicContact CB-CZ3 4.47Å; V635-W640 HydrophobicContact CG2-CE3 4.35Å; V635-W640 HydrophobicContact CG2-CZ3 4.35Å; V635-L643 HydrophobicContact CG1-CD1 4.18Å; V635-L643 HydrophobicContact CG2-CD1 4.31Å
636P88.9Confident91Very high3 Ų335.1 Ų35.12%0.01918%0.183CC..  trans-54.5142.3174-22.832.6000112.3W553 E638 R639 W640W553-P636 HydrophobicContact CD2-CG 3.51Å; W553-P636 HydrophobicContact CE3-CG 3.56Å; W553-P636 HydrophobicContact CG-CG 4Å; W553-P636 HydrophobicContact CH2-CG 3.99Å; W553-P636 HydrophobicContact CZ2-CG 3.99Å; W553-P636 HydrophobicContact CZ3-CB 4.46Å; W553-P636 HydrophobicContact CZ3-CG 3.78Å; P636-E638 HydrophobicContact CB-CG 4.29Å; P636-E638 VanDerWaalsContact CB-OE1 3.22Å; P636-E638 WeakPolarHBondContact CB-OE1 3.44Å; P636-E638 WeakPolarHBondContact CB-OE2 3.46Å; P636-E638 PolarHBondContact O-N 2.93Å; P636-R639 PolarHBondContact O-N 3.13Å; P636-W640 PolarHBondContact O-N 3.37Å; P636-W640 VanDerWaalsContact O-N 3.1Å
637S87.7Confident91.4Very high31 Ų3134.7 Ų34.722%0.21718%0.181CC..Hα-helixtrans-61.1-33-174.9-95.10000113.1R610 M611 R639 W640R610-S637 PolarHBondContact NE-OG 2.69Å; R610-S637 PolarHBondContact NH2-O 3.47Å; M611-S637 PolarHBondContact O-OG 2.94Å; S637-R639 VanDerWaalsContact C-N 3.31Å; S637-W640 PolarHBondContact O-N 3.31Å
638E87.1Confident91.7Very high107 Ų10737.3 Ų37.350%0.519%0.192SC..Hα-helixtrans-72.3-21.217865.4-83.6-164.700113.4H188 P636H188-E638 IonicContact CE1-OE1 2.91Å; H188-E638 PolarHBondContact CE1-OE1 3.25Å; H188-E638 IonicContact NE2-OE1 3.59Å; H188-E638 PolarHBondContact NE2-OE1 2.93Å; P636-E638 HydrophobicContact CB-CG 4.29Å; P636-E638 VanDerWaalsContact CB-OE1 3.22Å; P636-E638 WeakPolarHBondContact CB-OE1 3.44Å; P636-E638 WeakPolarHBondContact CB-OE2 3.46Å; P636-E638 PolarHBondContact O-N 2.93Å
639R91Very high91.7Very high31 Ų3141.5 Ų41.512%0.11721%0.209CC..Hα-helixtrans-98.2-14.5175.7-69.1-167.6170.8-145.3-9113.5L552 A555 D557 F560 V635 P636 S637 D641 I642L552-R639 WeakPolarHBondContact O-CD 3.46Å; A555-R639 PolarHBondContact O-NH1 2.94Å; A555-R639 PolarHBondContact O-NH2 3.45Å; D557-R639 IonicContact OD1-NH2 3.45Å; D557-R639 PolarHBondContact OD1-NH2 3.24Å; F560-R639 VanDerWaalsContact CD2-NH1 3.34Å; F560-R639 HydrophobicContact CE1-CB 4.35Å; F560-R639 HydrophobicContact CE2-CB 4.17Å; F560-R639 HydrophobicContact CZ-CB 3.8Å; F560-R639 HydrophobicContact CZ-CG 4.47Å; V635-R639 HydrophobicContact CG1-CB 4.07Å; P636-R639 PolarHBondContact O-N 3.13Å; S637-R639 VanDerWaalsContact C-N 3.31Å; R639-D641 VanDerWaalsContact C-N 3.34Å; R639-D641 PolarHBondContact O-N 3.16Å; R639-I642 WeakPolarHBondContact O-CG1 3.25Å; R639-I642 PolarHBondContact O-N 3.39Å
640W93.2Very high91.7Very high30 Ų3042.6 Ų42.611%0.11422%0.222CC..Hα-helixtrans-59.7-45.7-178.3-176.3-93.8000112.2L608 R610 V635 P636 S637 I642 L643 Q648L608-W640 HydrophobicContact CB-CZ3 4.18Å; R610-W640 HydrophobicContact CB-CD2 3.54Å; R610-W640 HydrophobicContact CB-CE3 3.71Å; R610-W640 HydrophobicContact CB-CG 3.97Å; R610-W640 HydrophobicContact CB-CH2 4.36Å; R610-W640 HydrophobicContact CB-CZ2 4.21Å; R610-W640 HydrophobicContact CB-CZ3 4.14Å; R610-W640 HydrophobicContact CG-CB 3.94Å; R610-W640 HydrophobicContact CG-CD2 3.82Å; R610-W640 HydrophobicContact CG-CE3 4.25Å; R610-W640 HydrophobicContact CG-CG 3.67Å; V635-W640 HydrophobicContact CB-CE3 4.04Å; V635-W640 HydrophobicContact CB-CZ3 4.47Å; V635-W640 HydrophobicContact CG2-CE3 4.35Å; V635-W640 HydrophobicContact CG2-CZ3 4.35Å; P636-W640 PolarHBondContact O-N 3.37Å; P636-W640 VanDerWaalsContact O-N 3.1Å; S637-W640 PolarHBondContact O-N 3.31Å; W640-I642 PolarHBondContact O-N 3.38Å; W640-L643 HydrophobicContact CD2-CD1 4.33Å; W640-L643 HydrophobicContact CE3-CD1 3.76Å; W640-L643 HydrophobicContact CZ3-CD1 4.07Å; W640-L643 WeakPolarHBondContact O-CB 3.24Å; W640-L643 PolarHBondContact O-N 3.5Å; W640-Q648 HydrophobicContact CZ2-CB 4.22Å; W640-Q648 WeakPolarHBondContact CZ2-O 3.08Å; W640-Q648 PolarHBondContact O-NE2 2.84Å
641D91.8Very high91.8Very high96 Ų9644 Ų4451%0.51323%0.23SC..THydrogen-bonded Turntrans-72.9-16-170.3-56.7-41.9000112.8R610 R639 Q648R610-D641 IonicContact CZ-OD1 3.21Å; R610-D641 IonicContact CZ-OD2 3.84Å; R610-D641 IonicContact NH1-OD1 2.92Å; R610-D641 PolarHBondContact NH1-OD1 3.4Å; R610-D641 IonicContact NH1-OD2 2.96Å; R610-D641 IonicContact NH2-OD1 2.61Å; R610-D641 PolarHBondContact NH2-OD1 2.58Å; R610-D641 IonicContact NH2-OD2 3.43Å; R610-D641 PolarHBondContact NH2-OD2 3.26Å; R639-D641 VanDerWaalsContact C-N 3.34Å; R639-D641 PolarHBondContact O-N 3.16Å; D641-Q648 PolarHBondContact O-NE2 2.92Å
642I93.3Very high92.1Very high75 Ų7548.2 Ų48.239%0.38525%0.245SC..THydrogen-bonded Turntrans-97.2-0.8176.460.5161.9000113.8F560 L561 R639 W640F560-I642 HydrophobicContact CD1-CD1 3.71Å; F560-I642 HydrophobicContact CD1-CG1 4.34Å; F560-I642 HydrophobicContact CE1-CD1 3.63Å; F560-I642 HydrophobicContact CE1-CG1 3.77Å; L561-I642 HydrophobicContact CD2-CB 4.24Å; L561-I642 HydrophobicContact CD2-CD1 4.32Å; L561-I642 VanDerWaalsContact CD2-O 3.32Å; L561-I642 WeakPolarHBondContact CD2-O 3.43Å; R639-I642 WeakPolarHBondContact O-CG1 3.25Å; R639-I642 PolarHBondContact O-N 3.39Å; W640-I642 PolarHBondContact O-N 3.38Å
643L94.6Very high92.5Very high7 Ų748.3 Ų48.34%0.03725%0.245CC..SBendtrans-68155.2175.2-76171.6000111.7F560 T564 L608 V635 W640 Q648F560-L643 HydrophobicContact CE1-CD2 3.95Å; F560-L643 HydrophobicContact CE1-CG 4.45Å; F560-L643 HydrophobicContact CE2-CD2 4.37Å; F560-L643 HydrophobicContact CZ-CD2 3.47Å; F560-L643 VanDerWaalsContact CZ-CD2 3.47Å; F560-L643 HydrophobicContact CZ-CG 4.04Å; T564-L643 HydrophobicContact CG2-CD2 3.65Å; L608-L643 HydrophobicContact CD1-CD1 3.98Å; L608-L643 HydrophobicContact CD1-CD2 4.01Å; V635-L643 HydrophobicContact CG1-CD1 4.18Å; V635-L643 HydrophobicContact CG2-CD1 4.31Å; W640-L643 HydrophobicContact CD2-CD1 4.33Å; W640-L643 HydrophobicContact CE3-CD1 3.76Å; W640-L643 HydrophobicContact CZ3-CD1 4.07Å; W640-L643 WeakPolarHBondContact O-CB 3.24Å; W640-L643 PolarHBondContact O-N 3.5Å; L643-Q648 HydrophobicContact CB-CG 3.77Å; L643-Q648 PolarHBondContact O-NE2 2.88Å
644P93.4Very high92.7Very high29 Ų2952.9 Ų52.919%0.18827%0.267CS..  trans-52.9140.5164.1-25.233.5000112.5S646 L647 Q648P644-S646 VanDerWaalsContact C-N 3.29Å; P644-S646 PolarHBondContact O-N 3.36Å; P644-L647 HydrophobicContact CB-CG 4.48Å; P644-L647 HydrophobicContact CG-CD1 4.28Å; P644-L647 PolarHBondContact O-N 3.1Å; P644-Q648 PolarHBondContact O-N 3Å; P644-Q648 VanDerWaalsContact O-N 3.1Å
645Q93.9Very high93.1Very high156 Ų15652.4 Ų52.473%0.72926%0.263SS*.Hα-helixtrans-57.7-38.1-175.8-71.7-176.4-8.800113.5L647 Q648 N649Q645-L647 VanDerWaalsContact C-N 3.32Å; Q645-L647 PolarHBondContact O-N 3.26Å; Q645-Q648 PolarHBondContact O-N 3.01Å; Q645-N649 WeakPolarHBondContact O-CB 3.34Å; Q645-N649 PolarHBondContact O-N 3.46Å; Q645-N649 PolarHBondContact O-ND2 3.43Å; Q645-N649 PolarHBondContact O-OD1 3.45Å
646S94.1Very high93.4Very high21 Ų2154.6 Ų54.615%0.14727%0.274CS..Hα-helixtrans-53.2-47.4173.748.30000112.3S568 P644 N649 E651S568-S646 WeakPolarHBondContact CB-OG 3.26Å; S568-S646 PolarHBondContact OG-OG 3.18Å; P644-S646 VanDerWaalsContact C-N 3.29Å; P644-S646 PolarHBondContact O-N 3.36Å; S646-N649 PolarHBondContact O-N 3.08Å; S646-E651 WeakPolarHBondContact CB-OE2 3.32Å; S646-E651 VanDerWaalsContact O-CB 3.26Å; S646-E651 WeakPolarHBondContact O-CB 3.46Å; S646-E651 VanDerWaalsContact O-CG 3.31Å; S646-E651 WeakPolarHBondContact O-CG 2.9Å; S646-E651 PolarHBondContact O-N 3.24Å
647L95.5Very high93.9Very high2 Ų254.5 Ų54.51%0.0127%0.273CS..Hα-helixtrans-70.9-36179.6-61.8-176.7000111.7T564 W567 L608 P644 Q645 N649 G650 F653T564-L647 WeakPolarHBondContact O-CD1 3.38Å; W567-L647 HydrophobicContact CB-CD1 4.42Å; L608-L647 HydrophobicContact CD1-CB 4.21Å; L608-L647 HydrophobicContact CD1-CD1 4.01Å; P644-L647 HydrophobicContact CB-CG 4.48Å; P644-L647 HydrophobicContact CG-CD1 4.28Å; P644-L647 PolarHBondContact O-N 3.1Å; Q645-L647 VanDerWaalsContact C-N 3.32Å; Q645-L647 PolarHBondContact O-N 3.26Å; L647-N649 VanDerWaalsContact C-N 3.28Å; L647-N649 PolarHBondContact O-N 3.42Å; L647-G650 PolarHBondContact O-N 3.15Å; L647-G650 VanDerWaalsContact O-N 3.14Å; L647-F653 HydrophobicContact CD2-CD1 3.89Å
648Q94Very high94.4Very high59 Ų5953.1 Ų53.128%0.27626%0.263SS..Hα-helixtrans-63.4-35172.7-63.6-171.137.700112.1W640 D641 L643 P644 Q645 G650W640-Q648 HydrophobicContact CZ2-CB 4.22Å; W640-Q648 WeakPolarHBondContact CZ2-O 3.08Å; W640-Q648 PolarHBondContact O-NE2 2.84Å; D641-Q648 PolarHBondContact O-NE2 2.92Å; L643-Q648 HydrophobicContact CB-CG 3.77Å; L643-Q648 PolarHBondContact O-NE2 2.88Å; P644-Q648 PolarHBondContact O-N 3Å; P644-Q648 VanDerWaalsContact O-N 3.1Å; Q645-Q648 PolarHBondContact O-N 3.01Å; Q648-G650 PolarHBondContact O-N 3.32Å
649N90.5Very high94.9Very high125 Ų12548.7 Ų48.767%0.66824%0.243SC*.THydrogen-bonded Turntrans-72.70176.3-65.8-21.2000113.4Q645 S646 L647Q645-N649 WeakPolarHBondContact O-CB 3.34Å; Q645-N649 PolarHBondContact O-N 3.46Å; Q645-N649 PolarHBondContact O-ND2 3.43Å; Q645-N649 PolarHBondContact O-OD1 3.45Å; S646-N649 PolarHBondContact O-N 3.08Å; L647-N649 VanDerWaalsContact C-N 3.28Å; L647-N649 PolarHBondContact O-N 3.42Å
650G90.6Very high95.3Very high28 Ų2847.3 Ų47.329%0.28924%0.238SC..THydrogen-bonded Turntrans79.521.9178.300000114.1L647 Q648L647-G650 PolarHBondContact O-N 3.15Å; L647-G650 VanDerWaalsContact O-N 3.14Å; Q648-G650 PolarHBondContact O-N 3.32Å
651E94.7Very high95.5Very high106 Ų10645.9 Ų45.950%0.49523%0.232SC..  trans-62.3150174.4-69.6-177-159.700112.1S646S646-E651 WeakPolarHBondContact CB-OE2 3.32Å; S646-E651 VanDerWaalsContact O-CB 3.26Å; S646-E651 WeakPolarHBondContact O-CB 3.46Å; S646-E651 VanDerWaalsContact O-CG 3.31Å; S646-E651 WeakPolarHBondContact O-CG 2.9Å; S646-E651 PolarHBondContact O-N 3.24Å
652W96.7Very high95.8Very high87 Ų8741.4 Ų41.433%0.3321%0.208SC..  trans-90.3133.3178.9-66.890.1000110.7K605 F606 R607 K630K605-W652 HydrophobicContact CB-CB 4.41Å; K605-W652 HydrophobicContact CB-CE3 3.95Å; K605-W652 HydrophobicContact CD-CB 4Å; K605-W652 HydrophobicContact CD-CD2 3.72Å; K605-W652 HydrophobicContact CD-CE3 3.8Å; K605-W652 HydrophobicContact CD-CG 3.81Å; K605-W652 HydrophobicContact CG-CD2 4Å; K605-W652 HydrophobicContact CG-CE3 3.51Å; K605-W652 HydrophobicContact CG-CG 4.46Å; K605-W652 HydrophobicContact CG-CZ3 4.06Å; K605-W652 WeakPolarHBondContact O-CZ3 3.31Å; F606-W652 VanDerWaalsContact C-CE3 3.44Å; F606-W652 CarbonylContact O-C 3.54Å; F606-W652 VanDerWaalsContact O-CA 3.28Å; F606-W652 WeakPolarHBondContact O-CA 3.19Å; R607-W652 HydrophobicContact CB-CD2 4.03Å; R607-W652 HydrophobicContact CB-CE3 3.79Å; R607-W652 HydrophobicContact CB-CH2 4.2Å; R607-W652 HydrophobicContact CB-CZ2 4.44Å; R607-W652 HydrophobicContact CB-CZ3 3.88Å; R607-W652 HydrophobicContact CG-CD2 4.48Å; R607-W652 HydrophobicContact CG-CE3 4.1Å; R607-W652 HydrophobicContact CG-CH2 3.6Å; R607-W652 HydrophobicContact CG-CZ2 4.03Å; R607-W652 HydrophobicContact CG-CZ3 3.65Å; K630-W652 HydrophobicContact CB-CH2 3.59Å; K630-W652 HydrophobicContact CB-CZ2 4.44Å; K630-W652 HydrophobicContact CB-CZ3 3.82Å; K630-W652 HydrophobicContact CD-CH2 4.05Å; K630-W652 HydrophobicContact CD-CZ2 4.08Å; K630-W652 HydrophobicContact CG-CH2 3.96Å; K630-W652 HydrophobicContact CG-CZ2 4.4Å; K630-W652 HydrophobicContact CG-CZ3 4.22Å
653F97.8Very high95.9Very high9 Ų937.8 Ų37.84%0.03919%0.19CC..BIsolated β-bridgetrans-116.9161.4171.167.6-84.3000111.9W567 A572 K605 F606 L608 L647 V655W567-F653 HydrophobicContact CB-CD2 4.07Å; W567-F653 HydrophobicContact CB-CE2 4.31Å; W567-F653 HydrophobicContact CB-CG 4.36Å; W567-F653 HydrophobicContact CD2-CE2 4.06Å; W567-F653 HydrophobicContact CD2-CZ 4.32Å; W567-F653 HydrophobicContact CE3-CE1 4.32Å; W567-F653 AromaticContact CE3-CE2 3.86Å; W567-F653 HydrophobicContact CE3-CE2 3.86Å; W567-F653 AromaticContact CE3-CZ 3.64Å; W567-F653 HydrophobicContact CE3-CZ 3.64Å; W567-F653 HydrophobicContact CG-CD2 4.42Å; W567-F653 HydrophobicContact CG-CE2 4.27Å; W567-F653 HydrophobicContact CZ3-CZ 4.08Å; W567-F653 VanDerWaalsContact O-CB 3.29Å; W567-F653 WeakPolarHBondContact O-CB 3.48Å; A572-F653 HydrophobicContact CB-CD2 4.41Å; A572-F653 HydrophobicContact CB-CE2 4.16Å; K605-F653 WeakPolarHBondContact CA-O 3.24Å; F606-F653 HydrophobicContact CB-CD1 4.17Å; F606-F653 HydrophobicContact CB-CD2 4.22Å; F606-F653 HydrophobicContact CB-CE1 3.68Å; F606-F653 HydrophobicContact CB-CE2 3.75Å; F606-F653 HydrophobicContact CB-CG 4.42Å; F606-F653 HydrophobicContact CB-CZ 3.45Å; F606-F653 VanDerWaalsContact CB-CZ 3.45Å; F606-F653 HydrophobicContact CG-CE2 4.4Å; F606-F653 HydrophobicContact CG-CZ 4.4Å; F606-F653 PolarHBondContact N-O 3.39Å; F606-F653 WeakPolarHBondContact O-CD1 3.49Å; F606-F653 PolarHBondContact O-N 2.91Å; L608-F653 HydrophobicContact CD2-CE1 3.9Å; L608-F653 HydrophobicContact CD2-CZ 4.22Å; L608-F653 HydrophobicContact CG-CE1 4.03Å; L647-F653 HydrophobicContact CD2-CD1 3.89Å; F653-V655 HydrophobicContact CE2-CG2 4.43Å
654Q97.2Very high95.6Very high97 Ų9737.6 Ų37.645%0.45319%0.189SC..  trans-100.9158177.8-69.7-174.6-20.800111.5G571 A572G571-Q654 CarbonylContact C-O 3.55Å; G571-Q654 WeakPolarHBondContact CA-O 3.15Å; A572-Q654 PolarHBondContact N-O 3.49Å
655V98.2Very high95.3Very high1 Ų137.1 Ų37.11%0.00619%0.185CC..EExtended strand (participates in β ladder)trans-112.5117170-179.70000109I544 L548 A572 V574 F606 F653 V657I544-V655 HydrophobicContact CG2-CG1 4.02Å; I544-V655 HydrophobicContact CG2-CG2 4.41Å; L548-V655 HydrophobicContact CD1-CG2 3.86Å; L548-V655 HydrophobicContact CD2-CG2 4.48Å; A572-V655 HydrophobicContact CB-CG1 4.48Å; A572-V655 HydrophobicContact CB-CG2 4.09Å; A572-V655 CarbonylContact O-C 3.51Å; A572-V655 WeakPolarHBondContact O-CA 3.43Å; V574-V655 HydrophobicContact CB-CG1 4.36Å; V574-V655 HydrophobicContact CG2-CG1 3.83Å; F606-V655 HydrophobicContact CD2-CB 4.32Å; F606-V655 HydrophobicContact CD2-CG2 3.36Å; F606-V655 HydrophobicContact CE1-CG2 4.48Å; F606-V655 HydrophobicContact CE2-CB 3.9Å; F606-V655 HydrophobicContact CE2-CG2 3.26Å; F606-V655 HydrophobicContact CG-CG2 4.07Å; F606-V655 HydrophobicContact CZ-CG2 3.88Å; F653-V655 HydrophobicContact CE2-CG2 4.43Å; V655-V657 HydrophobicContact CG1-CG2 3.87Å; V655-V657 PolarHBondContact O-N 3.36Å
656H97.8Very high95.1Very high46 Ų4632.9 Ų32.921%0.21317%0.165CC..EExtended strand (participates in β ladder)trans-8388.2174.5-65.4-76.5000110.2S570 A572 L573 V574 I658 Y694S570-H656 PolarHBondContact O-CD2 3.3Å; S570-H656 VanDerWaalsContact O-CD2 3.23Å; S570-H656 PolarHBondContact O-NE2 3.34Å; A572-H656 PolarHBondContact O-N 2.86Å; L573-H656 HydrophobicContact CD1-CB 4.35Å; V574-H656 PolarHBondContact N-O 3.21Å; H656-I658 PolarHBondContact O-N 3.08Å; H656-Y694 HydrophobicContact CB-CD2 4.19Å; H656-Y694 AromaticContact CD2-CD2 3.75Å; H656-Y694 AromaticContact CD2-CE2 3.8Å; H656-Y694 AromaticContact CG-CD2 3.96Å
657V98.4Very high95Very high1 Ų133.3 Ų33.31%0.00617%0.165CC..EExtended strand (participates in β ladder)trans-80116.3170.9-173.80000109.8I544 V574 L576 A597 L600 V655I544-V657 HydrophobicContact CD1-CG2 3.88Å; I544-V657 HydrophobicContact CG1-CG2 4.35Å; V574-V657 WeakPolarHBondContact O-CA 3.5Å; L576-V657 HydrophobicContact CB-CG1 4.14Å; L576-V657 HydrophobicContact CD2-CG1 4.37Å; A597-V657 HydrophobicContact CB-CG1 4.13Å; L600-V657 HydrophobicContact CB-CB 4.5Å; L600-V657 HydrophobicContact CB-CG2 3.93Å; L600-V657 HydrophobicContact CD1-CG2 4.02Å; V655-V657 HydrophobicContact CG1-CG2 3.87Å; V655-V657 PolarHBondContact O-N 3.36Å
658I98.5Very high94.8Very high3 Ų333.2 Ų33.22%0.01517%0.165CC..EExtended strand (participates in β ladder)trans-109.9112.5178.3-56.9-171.5000108.7L573 V574 L576 H656 A687 L690 L691L573-I658 HydrophobicContact CD1-CD1 3.61Å; L573-I658 HydrophobicContact CD1-CG1 3.99Å; V574-I658 PolarHBondContact O-N 3.21Å; L576-I658 PolarHBondContact N-O 3.35Å; H656-I658 PolarHBondContact O-N 3.08Å; I658-A687 HydrophobicContact CG2-CB 3.7Å; I658-L690 HydrophobicContact CD1-CB 3.96Å; I658-L690 HydrophobicContact CG1-CB 4.19Å; I658-L691 HydrophobicContact CD1-CB 3.84Å; I658-L691 HydrophobicContact CD1-CD1 4.05Å
659L98.7Very high94.7Very high14 Ų1432.2 Ų32.27%0.07316%0.164CC..EExtended strand (participates in β ladder)trans-89121.5-179.5173.765.4000110.6L576 L593 I594 A597 I683 A687L576-L659 HydrophobicContact CB-CD1 4.41Å; L576-L659 HydrophobicContact CD2-CD1 3.89Å; L576-L659 HydrophobicContact CG-CD1 3.86Å; L576-L659 CarbonylContact O-C 3.29Å; L576-L659 WeakPolarHBondContact O-CA 3.5Å; L593-L659 HydrophobicContact CB-CD1 4.38Å; L593-L659 HydrophobicContact CB-CD2 3.95Å; L593-L659 HydrophobicContact CD1-CD1 4.39Å; I594-L659 HydrophobicContact CG1-CD2 3.84Å; A597-L659 HydrophobicContact CB-CB 4.02Å; L659-I683 HydrophobicContact CD2-CG2 4.27Å; L659-I683 HydrophobicContact CG-CG2 3.96Å; L659-I683 VanDerWaalsContact O-CG2 3.26Å; L659-I683 WeakPolarHBondContact O-CG2 3.36Å; L659-A687 VanDerWaalsContact O-CB 3.25Å; L659-A687 WeakPolarHBondContact O-CB 3.3Å
660W98.6Very high94.8Very high2 Ų229.1 Ų29.11%0.00815%0.147CC..EExtended strand (participates in β ladder)trans-108.4146.8167.5-62.689.1000109.5S575 L576 H577 S578 N684 A687 L691 L717 L731 A735S575-W660 VanDerWaalsContact OG-CD1 3.23Å; S575-W660 PolarHBondContact OG-NE1 2.79Å; L576-W660 PolarHBondContact O-N 2.72Å; H577-W660 AromaticContact CE1-CD1 3.53Å; H577-W660 AromaticContact CE1-CG 3.83Å; H577-W660 AromaticContact ND1-CD1 3.95Å; H577-W660 AromaticContact ND1-CG 3.91Å; S578-W660 PolarHBondContact N-O 3.49Å; W660-N684 HydrophobicContact CE3-CB 4.16Å; W660-N684 HydrophobicContact CZ3-CB 4.26Å; W660-A687 HydrophobicContact CD2-CB 3.59Å; W660-A687 HydrophobicContact CE3-CB 3.75Å; W660-A687 HydrophobicContact CG-CB 4.18Å; W660-A687 HydrophobicContact CH2-CB 3.93Å; W660-A687 HydrophobicContact CZ2-CB 3.77Å; W660-A687 HydrophobicContact CZ3-CB 3.92Å; W660-L691 HydrophobicContact CZ2-CB 4.4Å; W660-L691 HydrophobicContact CZ2-CD2 3.87Å; W660-L717 HydrophobicContact CH2-CD1 4.29Å; W660-L717 HydrophobicContact CH2-CD2 3.91Å; W660-L717 HydrophobicContact CH2-CG 4.34Å; W660-L717 HydrophobicContact CZ2-CD2 4.19Å; W660-L731 HydrophobicContact CE3-CD1 4.4Å; W660-L731 HydrophobicContact CE3-CD2 4.37Å; W660-L731 HydrophobicContact CE3-CG 4.34Å; W660-L731 HydrophobicContact CZ3-CD1 3.94Å; W660-L731 HydrophobicContact CZ3-CD2 4.45Å; W660-L731 HydrophobicContact CZ3-CG 4.35Å; W660-A735 HydrophobicContact CD2-CB 3.96Å; W660-A735 HydrophobicContact CE3-CB 4.44Å; W660-A735 HydrophobicContact CG-CB 4.36Å; W660-A735 HydrophobicContact CH2-CB 4.48Å; W660-A735 HydrophobicContact CZ2-CB 4Å
661N98.2Very high94.9Very high0 Ų027.8 Ų27.80%013%0.134CC..EExtended strand (participates in β ladder)trans-133.6134.7173.3-171.970000112.1S578 L580 L590 E680 I683 N684S578-N661 VanDerWaalsContact CB-OD1 3.27Å; S578-N661 WeakPolarHBondContact CB-OD1 3.42Å; S578-N661 WeakPolarHBondContact O-CA 3.28Å; S578-N661 PolarHBondContact O-OD1 3.09Å; S578-N661 VanDerWaalsContact O-OD1 3.14Å; S578-N661 PolarHBondContact OG-OD1 3.12Å; L580-N661 PolarHBondContact O-ND2 2.81Å; L580-N661 VanDerWaalsContact O-ND2 3.12Å; L580-N661 PolarHBondContact O-OD1 2.89Å; L590-N661 HydrophobicContact CD2-CB 4.2Å; L590-N661 VanDerWaalsContact CD2-OD1 3.31Å; L590-N661 WeakPolarHBondContact CD2-OD1 3.45Å; N661-E680 PolarHBondContact ND2-OE2 2.81Å; N661-E680 VanDerWaalsContact O-CG 3.26Å; N661-E680 WeakPolarHBondContact O-CG 3.43Å; N661-I683 HydrophobicContact CB-CD1 4.01Å; N661-I683 HydrophobicContact CB-CG2 4.09Å; N661-N684 PolarHBondContact N-OD1 2.95Å; N661-N684 PolarHBondContact O-ND2 2.94Å; N661-N684 PolarHBondContact O-OD1 2.74Å
662V97.3Very high94.7Very high1 Ų125.1 Ų25.11%0.00612%0.122CC..  trans-136.9108.2166.1177.70000107.7S578 F579 V664 V729 L731 T732S578-V662 PolarHBondContact O-N 3.11Å; F579-V662 VanDerWaalsContact CA-O 3.29Å; F579-V662 WeakPolarHBondContact CA-O 3.33Å; F579-V662 WeakPolarHBondContact CD1-O 3.46Å; V662-V664 HydrophobicContact CG1-CG2 4.22Å; V662-V664 PolarHBondContact O-N 2.9Å; V662-V729 HydrophobicContact CG1-CG1 4.2Å; V662-L731 HydrophobicContact CG2-CD2 4.45Å; V662-T732 WeakPolarHBondContact CG2-OG1 3.34Å
663G95.2Very high94.5Very high0 Ų028.6 Ų28.60%014%0.14CC..  trans-66.8117.4-178.800000112.5L580 Q668 E680L580-G663 VanDerWaalsContact O-CA 3.24Å; L580-G663 WeakPolarHBondContact O-CA 3.22Å; G663-Q668 WeakPolarHBondContact O-CB 3.44Å; G663-Q668 VanDerWaalsContact O-CG 3.31Å; G663-Q668 WeakPolarHBondContact O-CG 3.2Å; G663-E680 PolarHBondContact N-OE2 2.75Å
664V89.4Confident94.2Very high2 Ų233.8 Ų33.81%0.01216%0.163CC..  trans-117.371.4-178.5-178.90000111F579 V662 V729 R756 V816 P817 Y820F579-V664 HydrophobicContact CB-CB 4.48Å; F579-V664 HydrophobicContact CD1-CB 4.34Å; F579-V664 HydrophobicContact CD1-CG2 3.69Å; F579-V664 HydrophobicContact CE1-CG2 4.32Å; F579-V664 PolarHBondContact O-N 2.99Å; V662-V664 HydrophobicContact CG1-CG2 4.22Å; V662-V664 PolarHBondContact O-N 2.9Å; V664-V729 HydrophobicContact CG2-CG1 3.83Å; V664-R756 WeakPolarHBondContact O-CD 3.32Å; V664-V816 HydrophobicContact CG1-CG1 4.12Å; V664-P817 HydrophobicContact CG1-CG 4.34Å; V664-Y820 HydrophobicContact CG1-CD2 4.21Å
665N87.1Confident93.8Very high19 Ų1937.3 Ų37.310%0.10218%0.179CC..SBendtrans-161.6175.3174.6-164.58.4000111.9D667 Q668 K727N665-D667 VanDerWaalsContact C-N 3.3Å; N665-D667 PolarHBondContact ND2-OD2 3.1Å; N665-D667 PolarHBondContact O-N 2.87Å; N665-Q668 PolarHBondContact O-N 3.49Å; N665-K727 PolarHBondContact O-NZ 3.46Å
666H89Confident93.4Very high68 Ų6841.1 Ų41.132%0.31520%0.197SC..Hα-helixtrans-58.4-39168.875.2-64.7000112.6Q668 S669 L670 F815H666-Q668 PolarHBondContact O-N 2.7Å; H666-S669 WeakPolarHBondContact O-CA 3.38Å; H666-S669 VanDerWaalsContact O-CB 3.31Å; H666-S669 WeakPolarHBondContact O-CB 3.3Å; H666-S669 PolarHBondContact O-N 3.36Å; H666-L670 PolarHBondContact O-N 3.15Å; H666-L670 VanDerWaalsContact O-N 3.16Å; H666-F815 HydrophobicContact CB-CB 4.27Å; H666-F815 HydrophobicContact CB-CD1 4.15Å; H666-F815 HydrophobicContact CB-CD2 3.97Å; H666-F815 HydrophobicContact CB-CE2 4.34Å; H666-F815 HydrophobicContact CB-CG 3.86Å
667D90.8Very high93.1Very high29 Ų2939 Ų3916%0.15519%0.187CC..Hα-helixtrans-60.6-32.6176.8-67.3-44000112.6S581 F583 N665 S669 L670 A671S581-D667 VanDerWaalsContact OG-CB 3.27Å; S581-D667 WeakPolarHBondContact OG-CB 3.32Å; F583-D667 HydrophobicContact CB-CB 4.26Å; F583-D667 WeakPolarHBondContact CB-O 3.03Å; N665-D667 VanDerWaalsContact C-N 3.3Å; N665-D667 PolarHBondContact ND2-OD2 3.1Å; N665-D667 PolarHBondContact O-N 2.87Å; D667-S669 VanDerWaalsContact C-N 3.34Å; D667-L670 WeakPolarHBondContact O-CB 3.4Å; D667-L670 PolarHBondContact O-N 3.4Å; D667-L670 VanDerWaalsContact O-N 3.17Å; D667-A671 PolarHBondContact O-N 3Å
668Q92.5Very high92.9Very high0 Ų042.4 Ų42.40%021%0.211CC..Hα-helixtrans-67.3-37.2173.5-175.1672.500111.5G663 N665 H666 L670 A671 I672 E680G663-Q668 WeakPolarHBondContact O-CB 3.44Å; G663-Q668 VanDerWaalsContact O-CG 3.31Å; G663-Q668 WeakPolarHBondContact O-CG 3.2Å; N665-Q668 PolarHBondContact O-N 3.49Å; H666-Q668 PolarHBondContact O-N 2.7Å; Q668-L670 PolarHBondContact O-N 2.77Å; Q668-A671 WeakPolarHBondContact O-CB 3.48Å; Q668-A671 PolarHBondContact O-N 3.47Å; Q668-I672 HydrophobicContact CG-CD1 4.2Å; Q668-I672 WeakPolarHBondContact O-CD1 3.34Å; Q668-I672 VanDerWaalsContact O-CG1 3.26Å; Q668-I672 WeakPolarHBondContact O-CG1 3.06Å; Q668-I672 PolarHBondContact O-N 2.82Å; Q668-E680 PolarHBondContact NE2-OE2 2.88Å
669S91.8Very high92.7Very high38 Ų3842.4 Ų42.427%0.26621%0.211SC..Hα-helixtrans-62.6-32.9173.1-71.10000112H666 D667 K673 K727H666-S669 WeakPolarHBondContact O-CA 3.38Å; H666-S669 VanDerWaalsContact O-CB 3.31Å; H666-S669 WeakPolarHBondContact O-CB 3.3Å; H666-S669 PolarHBondContact O-N 3.36Å; D667-S669 VanDerWaalsContact C-N 3.34Å; S669-K673 WeakPolarHBondContact O-CB 3.46Å; S669-K673 PolarHBondContact O-N 3.08Å; S669-K673 VanDerWaalsContact O-N 3.12Å; S669-K727 WeakPolarHBondContact OG-CE 3.36Å; S669-K727 PolarHBondContact OG-NZ 2.98Å
670L92.7Very high92.6Very high60 Ų6041.9 Ų41.931%0.31421%0.208SC..Hα-helixtrans-69.5-44.1171.3-62.1177.5000111.5F583 H666 D667 Q668 I672 K673 F674F583-L670 HydrophobicContact CD1-CB 3.81Å; F583-L670 HydrophobicContact CD1-CD1 4.14Å; F583-L670 HydrophobicContact CE1-CB 3.82Å; F583-L670 HydrophobicContact CE1-CD1 3.89Å; F583-L670 HydrophobicContact CG-CB 4.34Å; F583-L670 HydrophobicContact CZ-CB 4.32Å; H666-L670 PolarHBondContact O-N 3.15Å; H666-L670 VanDerWaalsContact O-N 3.16Å; D667-L670 WeakPolarHBondContact O-CB 3.4Å; D667-L670 PolarHBondContact O-N 3.4Å; D667-L670 VanDerWaalsContact O-N 3.17Å; Q668-L670 PolarHBondContact O-N 2.77Å; L670-I672 VanDerWaalsContact C-N 3.28Å; L670-I672 PolarHBondContact O-N 2.92Å; L670-K673 PolarHBondContact O-N 2.91Å; L670-K673 VanDerWaalsContact O-N 3.12Å; L670-F674 HydrophobicContact CB-CD2 4.18Å; L670-F674 HydrophobicContact CB-CE2 4.26Å; L670-F674 HydrophobicContact CD2-CE2 4.25Å; L670-F674 WeakPolarHBondContact O-CB 3.33Å; L670-F674 WeakPolarHBondContact O-CD2 3.16Å; L670-F674 PolarHBondContact O-N 3.33Å
671A92Very high92.5Very high0 Ų042.7 Ų42.70%021%0.213CC..Hα-helixtrans-55-45175.500000112C582 F583 D667 Q668 F674 Q675 E676 A677C582-A671 HydrophobicContact CB-CB 4.07Å; F583-A671 HydrophobicContact CB-CB 4.09Å; F583-A671 HydrophobicContact CD2-CB 4.44Å; D667-A671 PolarHBondContact O-N 3Å; Q668-A671 WeakPolarHBondContact O-CB 3.48Å; Q668-A671 PolarHBondContact O-N 3.47Å; A671-F674 CarbonylContact O-C 3.51Å; A671-F674 PolarHBondContact O-N 2.77Å; A671-Q675 CarbonylContact O-C 3.58Å; A671-Q675 PolarHBondContact O-N 3.15Å; A671-E676 HydrophobicContact CB-CB 4.16Å; A671-E676 PolarHBondContact O-N 3.38Å; A671-A677 HydrophobicContact CB-CB 4.22Å; A671-A677 PolarHBondContact O-N 3.07Å
672I90.8Very high92.4Very high50 Ų5047.3 Ų47.326%0.25624%0.235SC..Hα-helixtrans-62.4-48177.3-62.7159.5000110.3Q668 L670 F674 Q675 A677 W726Q668-I672 HydrophobicContact CG-CD1 4.2Å; Q668-I672 WeakPolarHBondContact O-CD1 3.34Å; Q668-I672 VanDerWaalsContact O-CG1 3.26Å; Q668-I672 WeakPolarHBondContact O-CG1 3.06Å; Q668-I672 PolarHBondContact O-N 2.82Å; L670-I672 VanDerWaalsContact C-N 3.28Å; L670-I672 PolarHBondContact O-N 2.92Å; I672-F674 VanDerWaalsContact C-N 3.28Å; I672-F674 PolarHBondContact O-N 2.85Å; I672-Q675 PolarHBondContact O-N 2.78Å; I672-Q675 VanDerWaalsContact O-N 3.13Å; I672-A677 HydrophobicContact CG1-CB 3.85Å; I672-W726 HydrophobicContact CD1-CB 3.41Å; I672-W726 VanDerWaalsContact CD1-CB 3.41Å; I672-W726 HydrophobicContact CD1-CD2 4.24Å; I672-W726 HydrophobicContact CD1-CG 3.53Å; I672-W726 HydrophobicContact CG1-CB 4.09Å; I672-W726 HydrophobicContact CG1-CD2 3.89Å; I672-W726 HydrophobicContact CG1-CG 3.66Å; I672-W726 HydrophobicContact CG2-CG 4.33Å
673K91.9Very high92.4Very high161 Ų16148.1 Ų48.170%0.724%0.238SC*.Hα-helixtrans-60.6-37.5179.9-174.6179.5179.4-1780112.4S669 L670S669-K673 WeakPolarHBondContact O-CB 3.46Å; S669-K673 PolarHBondContact O-N 3.08Å; S669-K673 VanDerWaalsContact O-N 3.12Å; L670-K673 PolarHBondContact O-N 2.91Å; L670-K673 VanDerWaalsContact O-N 3.12Å
674F92.2Very high92.6Very high118 Ų11848.4 Ų48.452%0.51824%0.24SC..THydrogen-bonded Turntrans-92.58.9179-65.6-62.3000113.6F583 L670 A671 I672 E676F583-F674 HydrophobicContact CE2-CB 4.46Å; F583-F674 AromaticContact CE2-CD2 3.81Å; F583-F674 HydrophobicContact CE2-CD2 3.81Å; F583-F674 HydrophobicContact CE2-CG 4.47Å; F583-F674 AromaticContact CZ-CD2 3.69Å; F583-F674 HydrophobicContact CZ-CD2 3.69Å; F583-F674 AromaticContact CZ-CE2 3.98Å; F583-F674 HydrophobicContact CZ-CE2 3.98Å; L670-F674 HydrophobicContact CB-CD2 4.18Å; L670-F674 HydrophobicContact CB-CE2 4.26Å; L670-F674 HydrophobicContact CD2-CE2 4.25Å; L670-F674 WeakPolarHBondContact O-CB 3.33Å; L670-F674 WeakPolarHBondContact O-CD2 3.16Å; L670-F674 PolarHBondContact O-N 3.33Å; A671-F674 CarbonylContact O-C 3.51Å; A671-F674 PolarHBondContact O-N 2.77Å; I672-F674 VanDerWaalsContact C-N 3.28Å; I672-F674 PolarHBondContact O-N 2.85Å; F674-E676 HydrophobicContact CB-CG 4.32Å; F674-E676 PolarHBondContact O-N 2.96Å
675Q89.5Confident93Very high171 Ų17152.4 Ų52.480%0.79926%0.259SS*.THydrogen-bonded Turntrans59.822.7179.9-54-179.99.100115A671 I672A671-Q675 CarbonylContact O-C 3.58Å; A671-Q675 PolarHBondContact O-N 3.15Å; I672-Q675 PolarHBondContact O-N 2.78Å; I672-Q675 VanDerWaalsContact O-N 3.13Å
676E89.3Confident93.5Very high80 Ų8053.1 Ų53.137%0.37427%0.27SS..THydrogen-bonded Turntrans-86.4-8.5175.9-70.9-68.9167.900112.9C582 F583 R587 A671 F674 S678C582-E676 WeakPolarHBondContact CB-O 3.44Å; F583-E676 HydrophobicContact CD2-CB 4.48Å; F583-E676 HydrophobicContact CD2-CG 4.43Å; R587-E676 IonicContact CZ-OE2 2.82Å; R587-E676 IonicContact NH1-OE2 3.76Å; R587-E676 PolarHBondContact NH1-OE2 2.81Å; R587-E676 VanDerWaalsContact NH1-OE2 3.15Å; A671-E676 HydrophobicContact CB-CB 4.16Å; A671-E676 PolarHBondContact O-N 3.38Å; F674-E676 HydrophobicContact CB-CG 4.32Å; F674-E676 PolarHBondContact O-N 2.96Å; E676-S678 PolarHBondContact O-N 2.97Å
677A91.6Very high93.9Very high1 Ų150 Ų501%0.00826%0.256CS..THydrogen-bonded Turntrans-74.3-6.1-177.600000114.1A671 I672 L679 E680 W726A671-A677 HydrophobicContact CB-CB 4.22Å; A671-A677 PolarHBondContact O-N 3.07Å; I672-A677 HydrophobicContact CG1-CB 3.85Å; A677-L679 PolarHBondContact O-N 3.33Å; A677-L679 VanDerWaalsContact O-N 3.16Å; A677-E680 WeakPolarHBondContact O-CB 3.49Å; A677-E680 PolarHBondContact O-N 3.15Å; A677-W726 HydrophobicContact CB-CD2 4.26Å; A677-W726 HydrophobicContact CB-CE3 3.94Å; A677-W726 HydrophobicContact CB-CH2 3.51Å; A677-W726 HydrophobicContact CB-CZ2 3.84Å; A677-W726 HydrophobicContact CB-CZ3 3.59Å; A677-W726 VanDerWaalsContact O-CH2 3.24Å; A677-W726 WeakPolarHBondContact O-CH2 3.48Å; A677-W726 WeakPolarHBondContact O-CZ3 3.34Å
678S93.8Very high94.3Very high73 Ų7349 Ų4951%0.5125%0.253SS..Hα-helixtrans-57.2-29.1178.555.90000113.6E676 E680 N681 E682E676-S678 PolarHBondContact O-N 2.97Å; S678-E680 VanDerWaalsContact C-N 3.26Å; S678-E680 PolarHBondContact O-N 3.48Å; S678-N681 WeakPolarHBondContact O-CB 3.09Å; S678-N681 PolarHBondContact O-N 2.59Å; S678-N681 VanDerWaalsContact O-N 3.13Å; S678-E682 PolarHBondContact O-N 2.99Å; S678-E682 VanDerWaalsContact O-N 3.11Å
679L94.4Very high94.5Very high4 Ų452.4 Ų52.42%0.02128%0.277CS..Hα-helixtrans-59.8-34.6174.7-179.362.6000112.4R587 L590 I594 A677 N681 E682 I683R587-L679 HydrophobicContact CG-CD2 4.14Å; L590-L679 HydrophobicContact CB-CD2 4.47Å; I594-L679 HydrophobicContact CD1-CD1 3.95Å; A677-L679 PolarHBondContact O-N 3.33Å; A677-L679 VanDerWaalsContact O-N 3.16Å; L679-N681 VanDerWaalsContact C-N 3.34Å; L679-E682 PolarHBondContact O-N 3.27Å; L679-I683 HydrophobicContact CD1-CD1 4.47Å; L679-I683 HydrophobicContact CD1-CG1 4.47Å; L679-I683 HydrophobicContact CG-CD1 4.09Å; L679-I683 VanDerWaalsContact O-CG1 3.26Å; L679-I683 WeakPolarHBondContact O-CG1 3.48Å; L679-I683 PolarHBondContact O-N 3.44Å
680E96.7Very high94.8Very high2 Ų252.7 Ų52.71%0.00928%0.275CS..Hα-helixtrans-63.7-40.7175.7-178.4169.111600111.4N661 G663 Q668 A677 S678 I683 N684 W726N661-E680 PolarHBondContact ND2-OE2 2.81Å; N661-E680 VanDerWaalsContact O-CG 3.26Å; N661-E680 WeakPolarHBondContact O-CG 3.43Å; G663-E680 PolarHBondContact N-OE2 2.75Å; Q668-E680 PolarHBondContact NE2-OE2 2.88Å; A677-E680 WeakPolarHBondContact O-CB 3.49Å; A677-E680 PolarHBondContact O-N 3.15Å; S678-E680 VanDerWaalsContact C-N 3.26Å; S678-E680 PolarHBondContact O-N 3.48Å; E680-I683 PolarHBondContact O-N 3.27Å; E680-N684 WeakPolarHBondContact O-CB 3.5Å; E680-N684 VanDerWaalsContact O-CG 3.27Å; E680-N684 PolarHBondContact O-N 2.75Å; E680-N684 PolarHBondContact O-ND2 3.34Å; E680-W726 HydrophobicContact CB-CZ3 4.15Å
681N96.3Very high95Very high20 Ų2049.9 Ų49.911%0.10726%0.261CS..Hα-helixtrans-64-44.9175-66.9-26.3000111.2S678 L679 I683 N684 Q685 H724 W726S678-N681 WeakPolarHBondContact O-CB 3.09Å; S678-N681 PolarHBondContact O-N 2.59Å; S678-N681 VanDerWaalsContact O-N 3.13Å; L679-N681 VanDerWaalsContact C-N 3.34Å; N681-I683 VanDerWaalsContact C-N 3.34Å; N681-I683 PolarHBondContact O-N 3.39Å; N681-N684 PolarHBondContact O-N 2.86Å; N681-Q685 VanDerWaalsContact O-CB 3.31Å; N681-Q685 WeakPolarHBondContact O-CB 3.36Å; N681-Q685 WeakPolarHBondContact O-CG 3.41Å; N681-Q685 PolarHBondContact O-N 2.81Å; N681-H724 PolarHBondContact ND2-N 3.49Å; N681-H724 PolarHBondContact OD1-N 2.83Å; N681-H724 VanDerWaalsContact OD1-N 3.09Å; N681-W726 WeakPolarHBondContact ND2-CH2 3.32Å
682E96.5Very high95.1Very high97 Ų9752.7 Ų52.745%0.45327%0.273SS..Hα-helixtrans-56.3-48177-178.9-172.5155.500111.1R331 S678 L679 G686R331-E682 IonicContact CZ-OE1 3.76Å; R331-E682 IonicContact NH1-OE1 2.84Å; R331-E682 PolarHBondContact NH1-OE1 2.87Å; R331-E682 IonicContact NH1-OE2 3.89Å; R331-E682 IonicContact NH2-OE1 3.82Å; R331-E682 PolarHBondContact NH2-OE1 3.09Å; R331-E682 VanDerWaalsContact NH2-OE1 3.09Å; R331-E682 IonicContact NH2-OE2 2.85Å; S678-E682 PolarHBondContact O-N 2.99Å; S678-E682 VanDerWaalsContact O-N 3.11Å; L679-E682 PolarHBondContact O-N 3.27Å; E682-G686 PolarHBondContact O-N 3.23Å; E682-G686 VanDerWaalsContact O-N 3.14Å
683I97.7Very high95.3Very high17 Ų1758.6 Ų58.69%0.08729%0.292CS..Hα-helixtrans-59.9-53.9178.1-67.1165.9000110.3L590 I594 L659 N661 L679 E680 N681 G686 A687L590-I683 HydrophobicContact CD2-CD1 4.2Å; I594-I683 HydrophobicContact CD1-CD1 3.97Å; I594-I683 HydrophobicContact CD1-CG1 4.02Å; I594-I683 HydrophobicContact CG1-CD1 4.23Å; I594-I683 HydrophobicContact CG1-CG1 4.17Å; L659-I683 HydrophobicContact CD2-CG2 4.27Å; L659-I683 HydrophobicContact CG-CG2 3.96Å; L659-I683 VanDerWaalsContact O-CG2 3.26Å; L659-I683 WeakPolarHBondContact O-CG2 3.36Å; N661-I683 HydrophobicContact CB-CD1 4.01Å; N661-I683 HydrophobicContact CB-CG2 4.09Å; L679-I683 HydrophobicContact CD1-CD1 4.47Å; L679-I683 HydrophobicContact CD1-CG1 4.47Å; L679-I683 HydrophobicContact CG-CD1 4.09Å; L679-I683 VanDerWaalsContact O-CG1 3.26Å; L679-I683 WeakPolarHBondContact O-CG1 3.48Å; L679-I683 PolarHBondContact O-N 3.44Å; E680-I683 PolarHBondContact O-N 3.27Å; N681-I683 VanDerWaalsContact C-N 3.34Å; N681-I683 PolarHBondContact O-N 3.39Å; I683-G686 PolarHBondContact O-N 3.24Å; I683-A687 WeakPolarHBondContact O-CB 3.35Å; I683-A687 PolarHBondContact O-N 2.98Å
684N98.2Very high95.5Very high6 Ų651.4 Ų51.43%0.03226%0.261CS..Hα-helixtrans-72.3-32.9-171.1-65.1-26.6000113.1W660 N661 E680 N681 A687 G688 N721 L731W660-N684 HydrophobicContact CE3-CB 4.16Å; W660-N684 HydrophobicContact CZ3-CB 4.26Å; N661-N684 PolarHBondContact N-OD1 2.95Å; N661-N684 PolarHBondContact O-ND2 2.94Å; N661-N684 PolarHBondContact O-OD1 2.74Å; E680-N684 WeakPolarHBondContact O-CB 3.5Å; E680-N684 VanDerWaalsContact O-CG 3.27Å; E680-N684 PolarHBondContact O-N 2.75Å; E680-N684 PolarHBondContact O-ND2 3.34Å; N681-N684 PolarHBondContact O-N 2.86Å; N684-A687 WeakPolarHBondContact O-CB 3.48Å; N684-A687 PolarHBondContact O-N 3.24Å; N684-G688 PolarHBondContact O-N 2.91Å; N684-N721 WeakPolarHBondContact CB-OD1 3.41Å; N684-N721 PolarHBondContact O-ND2 3.37Å; N684-L731 HydrophobicContact CB-CD2 4.19Å
685Q97.7Very high95.5Very high86 Ų8645.9 Ų45.940%0.40224%0.237SC..Hα-helixtrans-66.3-43.7172.5-71.9172.78.100111.7N681 A687 G688 S689N681-Q685 VanDerWaalsContact O-CB 3.31Å; N681-Q685 WeakPolarHBondContact O-CB 3.36Å; N681-Q685 WeakPolarHBondContact O-CG 3.41Å; N681-Q685 PolarHBondContact O-N 2.81Å; Q685-A687 VanDerWaalsContact C-N 3.31Å; Q685-A687 PolarHBondContact O-N 2.83Å; Q685-G688 PolarHBondContact O-N 3.22Å; Q685-S689 PolarHBondContact O-N 3.1Å; Q685-S689 VanDerWaalsContact O-N 3.08Å; Q685-S689 PolarHBondContact O-OG 2.89Å
686G97.7Very high95.5Very high34 Ų3443 Ų4335%0.35123%0.227SC..Hα-helixtrans-61.1-41.9173.200000111.8E682 I683 S689 L690E682-G686 PolarHBondContact O-N 3.23Å; E682-G686 VanDerWaalsContact O-N 3.14Å; I683-G686 PolarHBondContact O-N 3.24Å; G686-S689 PolarHBondContact O-N 2.98Å; G686-L690 WeakPolarHBondContact O-CG 3.46Å; G686-L690 PolarHBondContact O-N 3.28Å
687A98.4Very high95.6Very high2 Ų241.6 Ų41.62%0.01723%0.225CC..Hα-helixtrans-61.6-46.517700000112.4I658 L659 W660 I683 N684 Q685 S689 L690 L691I658-A687 HydrophobicContact CG2-CB 3.7Å; L659-A687 VanDerWaalsContact O-CB 3.25Å; L659-A687 WeakPolarHBondContact O-CB 3.3Å; W660-A687 HydrophobicContact CD2-CB 3.59Å; W660-A687 HydrophobicContact CE3-CB 3.75Å; W660-A687 HydrophobicContact CG-CB 4.18Å; W660-A687 HydrophobicContact CH2-CB 3.93Å; W660-A687 HydrophobicContact CZ2-CB 3.77Å; W660-A687 HydrophobicContact CZ3-CB 3.92Å; I683-A687 WeakPolarHBondContact O-CB 3.35Å; I683-A687 PolarHBondContact O-N 2.98Å; N684-A687 WeakPolarHBondContact O-CB 3.48Å; N684-A687 PolarHBondContact O-N 3.24Å; Q685-A687 VanDerWaalsContact C-N 3.31Å; Q685-A687 PolarHBondContact O-N 2.83Å; A687-S689 PolarHBondContact O-N 3.19Å; A687-L690 PolarHBondContact O-N 2.72Å; A687-L691 WeakPolarHBondContact O-CB 3.15Å; A687-L691 PolarHBondContact O-N 3.47Å
688G97.8Very high95.4Very high8 Ų841.5 Ų41.58%0.08223%0.225CC..Hα-helixtrans-57.7-46.9175.100000112.1N684 Q685 L690 L691 E692N684-G688 PolarHBondContact O-N 2.91Å; Q685-G688 PolarHBondContact O-N 3.22Å; G688-L690 VanDerWaalsContact C-N 3.34Å; G688-L690 PolarHBondContact O-N 2.87Å; G688-L691 PolarHBondContact O-N 3.02Å; G688-E692 WeakPolarHBondContact O-CG 3.44Å; G688-E692 PolarHBondContact O-N 3.44Å
689S97.7Very high94.9Very high72 Ų7241 Ų4150%0.50321%0.212SC..Hα-helixtrans-61.9-39.3178.2-58.50000112.9Q685 G686 A687 R693Q685-S689 PolarHBondContact O-N 3.1Å; Q685-S689 VanDerWaalsContact O-N 3.08Å; Q685-S689 PolarHBondContact O-OG 2.89Å; G686-S689 PolarHBondContact O-N 2.98Å; A687-S689 PolarHBondContact O-N 3.19Å; S689-R693 PolarHBondContact O-N 3.45Å; S689-R693 VanDerWaalsContact O-N 3.16Å
690L97.8Very high94Very high45 Ų4550.9 Ų50.924%0.23625%0.249CC..Hα-helixtrans-68.7-41.3176.4-72.3171.6000111.8I658 G686 A687 G688 R693 Y694I658-L690 HydrophobicContact CD1-CB 3.96Å; I658-L690 HydrophobicContact CG1-CB 4.19Å; G686-L690 WeakPolarHBondContact O-CG 3.46Å; G686-L690 PolarHBondContact O-N 3.28Å; A687-L690 PolarHBondContact O-N 2.72Å; G688-L690 VanDerWaalsContact C-N 3.34Å; G688-L690 PolarHBondContact O-N 2.87Å; L690-R693 PolarHBondContact O-N 2.78Å; L690-Y694 PolarHBondContact O-N 2.78Å
691L97Very high93Very high1 Ų156.3 Ų56.31%0.00527%0.274CS..Hα-helixtrans-68.1-40.3-179.7-175.758.3000111.1L573 I658 W660 A687 G688 R693 Y694 C695 L717 L738 L742L573-L691 HydrophobicContact CD1-CD1 4.44Å; L573-L691 HydrophobicContact CD2-CD1 4Å; I658-L691 HydrophobicContact CD1-CB 3.84Å; I658-L691 HydrophobicContact CD1-CD1 4.05Å; W660-L691 HydrophobicContact CZ2-CB 4.4Å; W660-L691 HydrophobicContact CZ2-CD2 3.87Å; A687-L691 WeakPolarHBondContact O-CB 3.15Å; A687-L691 PolarHBondContact O-N 3.47Å; G688-L691 PolarHBondContact O-N 3.02Å; L691-R693 PolarHBondContact O-N 3.13Å; L691-Y694 PolarHBondContact O-N 3.49Å; L691-C695 VanDerWaalsContact O-CB 3.24Å; L691-C695 WeakPolarHBondContact O-CB 3.35Å; L691-C695 PolarHBondContact O-N 3.21Å; L691-L717 HydrophobicContact CD2-CD2 3.76Å; L691-L738 HydrophobicContact CD2-CB 4.48Å; L691-L738 HydrophobicContact CD2-CD2 3.72Å; L691-L738 HydrophobicContact CD2-CG 4.15Å; L691-L738 HydrophobicContact CG-CD2 4.24Å; L691-L742 HydrophobicContact CD1-CD1 3.82Å
692E94.7Very high92.1Very high58 Ų5857 Ų5727%0.27128%0.277SS..Hα-helixtrans-59.6-45.1172.6-76.3-173.3178.200112.1G688 Y694 C695 L696 L714 R718G688-E692 WeakPolarHBondContact O-CG 3.44Å; G688-E692 PolarHBondContact O-N 3.44Å; E692-Y694 VanDerWaalsContact C-N 3.34Å; E692-Y694 PolarHBondContact O-N 2.86Å; E692-C695 WeakPolarHBondContact O-CB 3.25Å; E692-C695 PolarHBondContact O-N 3.02Å; E692-L696 WeakPolarHBondContact O-CG 3.45Å; E692-L696 PolarHBondContact O-N 3.24Å; E692-L714 HydrophobicContact CG-CD1 3.73Å; E692-L714 HydrophobicContact CG-CD2 4.19Å; E692-L714 HydrophobicContact CG-CG 4.46Å; E692-R718 IonicContact OE1-CZ 3.49Å; E692-R718 VanDerWaalsContact OE1-CZ 3.27Å; E692-R718 IonicContact OE1-NE 2.87Å; E692-R718 PolarHBondContact OE1-NE 2.91Å; E692-R718 IonicContact OE1-NH2 3.63Å; E692-R718 PolarHBondContact OE1-NH2 3.02Å; E692-R718 IonicContact OE2-NH2 3.53Å
693R94.8Very high90.8Very high174 Ų17464.2 Ų64.266%0.65730%0.3SS*.Hα-helixtrans-60.8-43.9176.4-171.9-174.1-57.7179.31.9111.8S689 L690 L691 L696 S697S689-R693 PolarHBondContact O-N 3.45Å; S689-R693 VanDerWaalsContact O-N 3.16Å; L690-R693 PolarHBondContact O-N 2.78Å; L691-R693 PolarHBondContact O-N 3.13Å; R693-L696 PolarHBondContact O-N 3.46Å; R693-S697 PolarHBondContact O-N 2.84Å; R693-S697 VanDerWaalsContact O-N 3.15Å
694Y95.5Very high89.7Confident10 Ų1069.3 Ų69.34%0.03932%0.324CS..Hα-helixtrans-64-44.5176.5-175.4-86.8000111.2S570 G571 L573 H656 L690 L691 E692 L696 S697 A698 L742S570-Y694 WeakPolarHBondContact O-CE2 3.36Å; G571-Y694 WeakPolarHBondContact O-CE2 3.34Å; G571-Y694 PolarHBondContact O-OH 3.5Å; L573-Y694 HydrophobicContact CB-CD1 4.3Å; L573-Y694 HydrophobicContact CB-CD2 4.49Å; L573-Y694 HydrophobicContact CB-CE1 3.76Å; L573-Y694 HydrophobicContact CB-CE2 3.96Å; L573-Y694 HydrophobicContact CD1-CD1 4.33Å; L573-Y694 HydrophobicContact CD1-CD2 4.45Å; L573-Y694 HydrophobicContact CD1-CG 4.24Å; L573-Y694 HydrophobicContact CD2-CD1 3.79Å; L573-Y694 HydrophobicContact CD2-CE1 3.75Å; L573-Y694 HydrophobicContact CG-CD1 4.37Å; L573-Y694 HydrophobicContact CG-CE1 4.24Å; H656-Y694 HydrophobicContact CB-CD2 4.19Å; H656-Y694 AromaticContact CD2-CD2 3.75Å; H656-Y694 AromaticContact CD2-CE2 3.8Å; H656-Y694 AromaticContact CG-CD2 3.96Å; L690-Y694 PolarHBondContact O-N 2.78Å; L691-Y694 PolarHBondContact O-N 3.49Å; E692-Y694 VanDerWaalsContact C-N 3.34Å; E692-Y694 PolarHBondContact O-N 2.86Å; Y694-L696 VanDerWaalsContact C-N 3.33Å; Y694-L696 PolarHBondContact O-N 3.2Å; Y694-S697 WeakPolarHBondContact O-CB 3.31Å; Y694-S697 PolarHBondContact O-N 3.21Å; Y694-A698 HydrophobicContact CD1-CB 4.31Å; Y694-A698 HydrophobicContact CE1-CB 3.96Å; Y694-A698 WeakPolarHBondContact O-CB 3.12Å; Y694-A698 PolarHBondContact O-N 3Å; Y694-L742 HydrophobicContact CD1-CD1 4.42Å; Y694-L742 HydrophobicContact CE1-CB 4.23Å
695C92.8Very high89Confident2 Ų270.3 Ų70.31%0.01433%0.327CS..Hα-helixtrans-55.7-45.7176.6-173.70000111.7L691 E692 S697 A698 R699 L742L691-C695 VanDerWaalsContact O-CB 3.24Å; L691-C695 WeakPolarHBondContact O-CB 3.35Å; L691-C695 PolarHBondContact O-N 3.21Å; E692-C695 WeakPolarHBondContact O-CB 3.25Å; E692-C695 PolarHBondContact O-N 3.02Å; C695-S697 VanDerWaalsContact C-N 3.32Å; C695-S697 PolarHBondContact O-N 3.26Å; C695-A698 PolarHBondContact O-N 2.93Å; C695-R699 WeakPolarHBondContact O-CB 3.18Å; C695-R699 WeakPolarHBondContact O-CG 3.17Å; C695-R699 PolarHBondContact O-N 3.05Å; C695-R699 PolarHBondContact SG-NE 2.74Å; C695-L742 HydrophobicContact CB-CD1 4Å; C695-L742 HydrophobicContact CB-CD2 4.34Å
696L89.9Confident88.5Confident111 Ų11171.3 Ų71.358%0.58133%0.332SS*.Hα-helixtrans-63-35.8175.5-69.9172.9000113.2E692 R693 Y694 R700E692-L696 WeakPolarHBondContact O-CG 3.45Å; E692-L696 PolarHBondContact O-N 3.24Å; R693-L696 PolarHBondContact O-N 3.46Å; Y694-L696 VanDerWaalsContact C-N 3.33Å; Y694-L696 PolarHBondContact O-N 3.2Å; L696-R700 WeakPolarHBondContact O-CG 3.42Å
697S90.1Very high88Confident50 Ų5076 Ų7635%0.3535%0.345SS..Hα-helixtrans-68.6-49.6176.6-169.10000111.4S570 R693 Y694 C695 R700S570-S697 PolarHBondContact OG-OG 3.16Å; R693-S697 PolarHBondContact O-N 2.84Å; R693-S697 VanDerWaalsContact O-N 3.15Å; Y694-S697 WeakPolarHBondContact O-CB 3.31Å; Y694-S697 PolarHBondContact O-N 3.21Å; C695-S697 VanDerWaalsContact C-N 3.32Å; C695-S697 PolarHBondContact O-N 3.26Å; S697-R700 PolarHBondContact O-N 2.64Å
698A88.3Confident87.6Confident0 Ų083.4 Ų83.40%038%0.379CS..Hα-helixtrans-68.9-40.3-174.600000112.6L566 Y694 C695 R700 Q701 E702 F705L566-A698 HydrophobicContact CD2-CB 3.88Å; Y694-A698 HydrophobicContact CD1-CB 4.31Å; Y694-A698 HydrophobicContact CE1-CB 3.96Å; Y694-A698 WeakPolarHBondContact O-CB 3.12Å; Y694-A698 PolarHBondContact O-N 3Å; C695-A698 PolarHBondContact O-N 2.93Å; A698-R700 VanDerWaalsContact C-N 3.26Å; A698-R700 PolarHBondContact O-N 3.02Å; A698-Q701 PolarHBondContact O-N 3.24Å; A698-E702 PolarHBondContact O-N 2.89Å; A698-F705 HydrophobicContact CB-CE2 3.82Å
699R82.6Confident87.3Confident63 Ų6387.5 Ų87.524%0.23840%0.395CS..Hα-helixtrans-60.5-29.4178.4-77.2177.7-176.6-151.44.5114.3C695 Q701 E707C695-R699 WeakPolarHBondContact O-CB 3.18Å; C695-R699 WeakPolarHBondContact O-CG 3.17Å; C695-R699 PolarHBondContact O-N 3.05Å; C695-R699 PolarHBondContact SG-NE 2.74Å; R699-Q701 PolarHBondContact O-N 3.41Å; R699-E707 IonicContact NH1-OE1 3.83Å
700R76.7Confident87.1Confident211 Ų21184.1 Ų84.180%0.79637%0.371SS*.THydrogen-bonded Turntrans-69.2-17.8-179.5-74.5177.3178.1-178.60.2113.1L696 S697 A698L696-R700 WeakPolarHBondContact O-CG 3.42Å; S697-R700 PolarHBondContact O-N 2.64Å; A698-R700 VanDerWaalsContact C-N 3.26Å; A698-R700 PolarHBondContact O-N 3.02Å
701Q74.2Confident86.8Confident116 Ų11687.9 Ų87.954%0.54239%0.385SS..THydrogen-bonded Turntrans-117.6-31.5-167.7-58.9-62.6-18.600112.9H569 A698 R699H569-Q701 HydrophobicContact CB-CG 4.29Å; A698-Q701 PolarHBondContact O-N 3.24Å; R699-Q701 PolarHBondContact O-N 3.41Å
702E76.8Confident86.7Confident35 Ų3593.9 Ų93.916%0.16441%0.413CS..  trans-109.5111.1-170.8-156.255.2-113.600113L562 S565 L566 A698 Q704 F705L562-E702 HydrophobicContact CD1-CG 3.64Å; S565-E702 PolarHBondContact OG-OE2 3.42Å; L566-E702 HydrophobicContact CD2-CB 4.4Å; A698-E702 PolarHBondContact O-N 2.89Å; E702-Q704 VanDerWaalsContact C-N 3.3Å; E702-Q704 PolarHBondContact O-N 3.4Å; E702-F705 HydrophobicContact CB-CD2 4.03Å; E702-F705 HydrophobicContact CB-CE2 3.9Å; E702-F705 HydrophobicContact CB-CG 4.45Å; E702-F705 HydrophobicContact CB-CZ 4.22Å; E702-F705 HydrophobicContact CG-CE1 4.41Å; E702-F705 HydrophobicContact CG-CZ 4.37Å
703R69.8Low86.7Confident248 Ų24891.1 Ų91.194%0.93640%0.401SS*.THydrogen-bonded Turntrans-75-17.2-174.5-66.3-176.6-178.7179.61113.9F705R703-F705 PolarHBondContact O-N 3.12Å
704Q76Confident86.8Confident124 Ų12483.6 Ų83.658%0.57937%0.374SS*.THydrogen-bonded Turntrans-74.1-11.9-178.8-65.6-175.5-15.300113.1E702 E706E702-Q704 VanDerWaalsContact C-N 3.3Å; E702-Q704 PolarHBondContact O-N 3.4Å; Q704-E706 PolarHBondContact O-N 3.21Å
705F83.3Confident86.8Confident26 Ų2686.4 Ų86.411%0.11439%0.389CS..SBendtrans-72.8121.9-178.9-73.9-14.1000112.4L562 L566 A698 E702 R703 E707 I710 M741 L742L562-F705 HydrophobicContact CD1-CE1 4.04Å; L566-F705 HydrophobicContact CD1-CZ 3.94Å; L566-F705 HydrophobicContact CD2-CE2 4.14Å; L566-F705 HydrophobicContact CD2-CZ 3.91Å; L566-F705 HydrophobicContact CG-CZ 4.5Å; A698-F705 HydrophobicContact CB-CE2 3.82Å; E702-F705 HydrophobicContact CB-CD2 4.03Å; E702-F705 HydrophobicContact CB-CE2 3.9Å; E702-F705 HydrophobicContact CB-CG 4.45Å; E702-F705 HydrophobicContact CB-CZ 4.22Å; E702-F705 HydrophobicContact CG-CE1 4.41Å; E702-F705 HydrophobicContact CG-CZ 4.37Å; R703-F705 PolarHBondContact O-N 3.12Å; F705-E707 VanDerWaalsContact C-N 3.35Å; F705-E707 PolarHBondContact O-N 3.46Å; F705-I710 HydrophobicContact CB-CD1 3.61Å; F705-I710 HydrophobicContact CD1-CD1 4.41Å; F705-I710 HydrophobicContact CD2-CD1 4.27Å; F705-I710 HydrophobicContact CG-CD1 3.86Å; F705-M741 WeakPolarHBondContact CE1-O 3.34Å; F705-L742 HydrophobicContact CE2-CD2 4.23Å
706E86.5Confident87Confident108 Ų10890.8 Ų90.851%0.50541%0.41SS..  trans-71.688172.7-63.3-178.8128.300109.9Q704 E708 K709 I710Q704-E706 PolarHBondContact O-N 3.21Å; E706-E708 VanDerWaalsContact C-N 3.29Å; E706-E708 PolarHBondContact O-N 2.71Å; E706-K709 HydrophobicContact CB-CB 4.16Å; E706-K709 HydrophobicContact CB-CD 4.42Å; E706-K709 HydrophobicContact CB-CG 4.18Å; E706-K709 PolarHBondContact O-N 2.91Å; E706-K709 VanDerWaalsContact O-N 3.12Å; E706-K709 WeakPolarHBondContact OE1-CE 3.41Å; E706-K709 IonicContact OE1-NZ 2.83Å; E706-K709 PolarHBondContact OE1-NZ 3.18Å; E706-K709 WeakPolarHBondContact OE2-CD 3.15Å; E706-K709 WeakPolarHBondContact OE2-CE 3.24Å; E706-K709 IonicContact OE2-NZ 2.7Å; E706-K709 PolarHBondContact OE2-NZ 3.49Å; E706-I710 WeakPolarHBondContact O-CG1 3.24Å; E706-I710 PolarHBondContact O-N 2.92Å
707E86.4Confident87.4Confident132 Ų13285.7 Ų85.762%0.61738%0.383SS*.Hα-helixtrans-54.3-42.8-169.9-175.2172.2-168.500113.5R699 F705 I710 K711R699-E707 IonicContact NH1-OE1 3.83Å; F705-E707 VanDerWaalsContact C-N 3.35Å; F705-E707 PolarHBondContact O-N 3.46Å; E707-I710 PolarHBondContact O-N 2.91Å; E707-K711 WeakPolarHBondContact O-CB 3.48Å; E707-K711 PolarHBondContact O-N 2.73Å
708E90.5Very high87.7Confident157 Ų15788.9 Ų88.973%0.73439%0.387SS*.Hα-helixtrans-62.5-48.9178.8-66-177.2166.800111.3E706 I710 K711 E712E706-E708 VanDerWaalsContact C-N 3.29Å; E706-E708 PolarHBondContact O-N 2.71Å; E708-I710 PolarHBondContact O-N 3.12Å; E708-K711 WeakPolarHBondContact O-CB 3.5Å; E708-K711 PolarHBondContact O-N 3.02Å; E708-K711 VanDerWaalsContact O-N 3.12Å; E708-E712 WeakPolarHBondContact O-CG 3.4Å; E708-E712 PolarHBondContact O-N 2.92Å
709K92.1Very high88.1Confident94 Ų9494.8 Ų94.841%0.40942%0.415SS..Hα-helixtrans-64.8-38.5179.5-60.7-162.3-158.5154.10112.3E706 K711 A713 M741E706-K709 HydrophobicContact CB-CB 4.16Å; E706-K709 HydrophobicContact CB-CD 4.42Å; E706-K709 HydrophobicContact CB-CG 4.18Å; E706-K709 PolarHBondContact O-N 2.91Å; E706-K709 VanDerWaalsContact O-N 3.12Å; E706-K709 WeakPolarHBondContact OE1-CE 3.41Å; E706-K709 IonicContact OE1-NZ 2.83Å; E706-K709 PolarHBondContact OE1-NZ 3.18Å; E706-K709 WeakPolarHBondContact OE2-CD 3.15Å; E706-K709 WeakPolarHBondContact OE2-CE 3.24Å; E706-K709 IonicContact OE2-NZ 2.7Å; E706-K709 PolarHBondContact OE2-NZ 3.49Å; K709-K711 VanDerWaalsContact C-N 3.32Å; K709-A713 VanDerWaalsContact O-CB 3.24Å; K709-A713 WeakPolarHBondContact O-CB 3.17Å; K709-A713 PolarHBondContact O-N 3.35Å; K709-M741 HydrophobicContact CB-CE 3.86Å
710I92.6Very high88.8Confident2 Ų293 Ų931%0.0141%0.41CS..Hα-helixtrans-66.7-38.4175.9-59.5171.7000109.9F705 E706 E707 E708 A713 L714 L738 M741 L742F705-I710 HydrophobicContact CB-CD1 3.61Å; F705-I710 HydrophobicContact CD1-CD1 4.41Å; F705-I710 HydrophobicContact CD2-CD1 4.27Å; F705-I710 HydrophobicContact CG-CD1 3.86Å; E706-I710 WeakPolarHBondContact O-CG1 3.24Å; E706-I710 PolarHBondContact O-N 2.92Å; E707-I710 PolarHBondContact O-N 2.91Å; E708-I710 PolarHBondContact O-N 3.12Å; I710-A713 PolarHBondContact O-N 2.74Å; I710-L714 VanDerWaalsContact O-CB 3.24Å; I710-L714 WeakPolarHBondContact O-CB 3.5Å; I710-L714 PolarHBondContact O-N 3.47Å; I710-L738 HydrophobicContact CG2-CD1 3.65Å; I710-M741 HydrophobicContact CB-CE 4.39Å; I710-M741 HydrophobicContact CG1-CB 4.45Å; I710-M741 HydrophobicContact CG1-CE 3.77Å; I710-L742 HydrophobicContact CD1-CD2 4.28Å; I710-L742 HydrophobicContact CG2-CD2 4.24Å
711K92.4Very high89.7Confident123 Ų12384.3 Ų84.354%0.53538%0.379SS..Hα-helixtrans-64.6-48.2177.2-174.7-177.1176.2-173.70111.2E707 E708 K709 A713 L714 D715E707-K711 WeakPolarHBondContact O-CB 3.48Å; E707-K711 PolarHBondContact O-N 2.73Å; E708-K711 WeakPolarHBondContact O-CB 3.5Å; E708-K711 PolarHBondContact O-N 3.02Å; E708-K711 VanDerWaalsContact O-N 3.12Å; K709-K711 VanDerWaalsContact C-N 3.32Å; K711-A713 VanDerWaalsContact C-N 3.34Å; K711-A713 PolarHBondContact O-N 3.03Å; K711-L714 WeakPolarHBondContact O-CB 3.42Å; K711-L714 PolarHBondContact O-N 2.92Å; K711-D715 PolarHBondContact O-N 3.14Å
712E95.5Very high90.8Very high127 Ų12783.3 Ų83.359%0.59337%0.374SS*.Hα-helixtrans-58-46.8174.7-71.1174.6176.900111.7E708 L714 D715 E716E708-E712 WeakPolarHBondContact O-CG 3.4Å; E708-E712 PolarHBondContact O-N 2.92Å; E712-L714 VanDerWaalsContact C-N 3.27Å; E712-L714 PolarHBondContact O-N 2.89Å; E712-D715 PolarHBondContact O-N 3.33Å; E712-E716 WeakPolarHBondContact O-CB 3.31Å; E712-E716 PolarHBondContact O-N 3.32Å
713A94.8Very high91.5Very high1 Ų184.6 Ų84.61%0.00839%0.386CS..Hα-helixtrans-63.1-35.2178.500000112.3K709 I710 K711 L717 Q734 L738 M741K709-A713 VanDerWaalsContact O-CB 3.24Å; K709-A713 WeakPolarHBondContact O-CB 3.17Å; K709-A713 PolarHBondContact O-N 3.35Å; I710-A713 PolarHBondContact O-N 2.74Å; K711-A713 VanDerWaalsContact C-N 3.34Å; K711-A713 PolarHBondContact O-N 3.03Å; A713-L717 WeakPolarHBondContact O-CB 3.21Å; A713-L717 PolarHBondContact O-N 3.38Å; A713-Q734 VanDerWaalsContact CA-NE2 3.28Å; A713-Q734 PolarHBondContact O-NE2 3.06Å; A713-L738 HydrophobicContact CB-CD1 4.17Å; A713-M741 HydrophobicContact CB-CE 4.3Å; A713-M741 HydrophobicContact CB-SD 4.07Å
714L95.4Very high92.5Very high16 Ų1679 Ų798%0.08437%0.37CS..Hα-helixtrans-70.5-40.6175.4-177.167.1000112E692 I710 K711 E712 L717 R718 L738E692-L714 HydrophobicContact CG-CD1 3.73Å; E692-L714 HydrophobicContact CG-CD2 4.19Å; E692-L714 HydrophobicContact CG-CG 4.46Å; I710-L714 VanDerWaalsContact O-CB 3.24Å; I710-L714 WeakPolarHBondContact O-CB 3.5Å; I710-L714 PolarHBondContact O-N 3.47Å; K711-L714 WeakPolarHBondContact O-CB 3.42Å; K711-L714 PolarHBondContact O-N 2.92Å; E712-L714 VanDerWaalsContact C-N 3.27Å; E712-L714 PolarHBondContact O-N 2.89Å; L714-L717 HydrophobicContact CD1-CD2 4.46Å; L714-L717 WeakPolarHBondContact O-CB 3.3Å; L714-L717 PolarHBondContact O-N 2.92Å; L714-R718 WeakPolarHBondContact O-CG 3.06Å; L714-R718 PolarHBondContact O-N 3.42Å; L714-L738 HydrophobicContact CB-CD2 4.25Å; L714-L738 HydrophobicContact CD1-CD2 3.76Å
715D96.5Very high93.1Very high69 Ų6977.6 Ų77.637%0.36936%0.363SS..Hα-helixtrans-66.1-40.4177-70.5-25.8000111.4K711 E712 R718 H719K711-D715 PolarHBondContact O-N 3.14Å; E712-D715 PolarHBondContact O-N 3.33Å; D715-R718 WeakPolarHBondContact O-CB 3.23Å; D715-R718 PolarHBondContact O-N 2.91Å; D715-R718 IonicContact OD1-CZ 3.32Å; D715-R718 IonicContact OD1-NH1 2.8Å; D715-R718 PolarHBondContact OD1-NH1 3.44Å; D715-H719 PolarHBondContact O-N 3.35Å; D715-H719 VanDerWaalsContact O-N 3.15Å
716E96.9Very high93.3Very high94 Ų9479.6 Ų79.644%0.43937%0.37SS..Hα-helixtrans-61.9-42170.6-178.8178.5-166.200111.7E712 R718 H719 L720 Q734 R737E712-E716 WeakPolarHBondContact O-CB 3.31Å; E712-E716 PolarHBondContact O-N 3.32Å; E716-R718 VanDerWaalsContact C-N 3.33Å; E716-R718 PolarHBondContact O-N 2.84Å; E716-H719 PolarHBondContact O-N 3.25Å; E716-L720 HydrophobicContact CG-CD1 4.08Å; E716-L720 WeakPolarHBondContact O-CG 3.46Å; E716-L720 PolarHBondContact O-N 2.96Å; E716-Q734 HydrophobicContact CG-CG 4.25Å; E716-Q734 VanDerWaalsContact OE2-CD 3.27Å; E716-Q734 PolarHBondContact OE2-NE2 3.46Å; E716-Q734 PolarHBondContact OE2-OE1 2.96Å; E716-R737 IonicContact OE2-NH1 3.52Å; E716-R737 PolarHBondContact OE2-NH1 2.79Å
717L97.5Very high93.4Very high4 Ų476.4 Ų76.42%0.02136%0.355CS..Hα-helixtrans-61.4-41.7176.4-17572.7000111.7W660 L691 A713 L714 L720 N721 L731 Q734 A735 L738W660-L717 HydrophobicContact CH2-CD1 4.29Å; W660-L717 HydrophobicContact CH2-CD2 3.91Å; W660-L717 HydrophobicContact CH2-CG 4.34Å; W660-L717 HydrophobicContact CZ2-CD2 4.19Å; L691-L717 HydrophobicContact CD2-CD2 3.76Å; A713-L717 WeakPolarHBondContact O-CB 3.21Å; A713-L717 PolarHBondContact O-N 3.38Å; L714-L717 HydrophobicContact CD1-CD2 4.46Å; L714-L717 WeakPolarHBondContact O-CB 3.3Å; L714-L717 PolarHBondContact O-N 2.92Å; L717-L720 PolarHBondContact O-N 2.9Å; L717-N721 VanDerWaalsContact O-CB 3.23Å; L717-N721 WeakPolarHBondContact O-CB 3.26Å; L717-N721 PolarHBondContact O-N 3.14Å; L717-L731 HydrophobicContact CD1-CD1 3.64Å; L717-L731 HydrophobicContact CG-CD1 4.46Å; L717-Q734 HydrophobicContact CB-CG 4.02Å; L717-Q734 HydrophobicContact CD1-CB 4.09Å; L717-Q734 HydrophobicContact CD1-CG 3.99Å; L717-A735 HydrophobicContact CD1-CB 3.83Å; L717-L738 HydrophobicContact CD2-CD2 3.81Å
718R96.7Very high93.7Very high117 Ų11771.7 Ų71.744%0.44233%0.334SS..Hα-helixtrans-60-46177.5-74165.3174.3168-8.1111.7E692 L714 D715 E716 L720 N721 E722E692-R718 IonicContact OE1-CZ 3.49Å; E692-R718 VanDerWaalsContact OE1-CZ 3.27Å; E692-R718 IonicContact OE1-NE 2.87Å; E692-R718 PolarHBondContact OE1-NE 2.91Å; E692-R718 IonicContact OE1-NH2 3.63Å; E692-R718 PolarHBondContact OE1-NH2 3.02Å; E692-R718 IonicContact OE2-NH2 3.53Å; L714-R718 WeakPolarHBondContact O-CG 3.06Å; L714-R718 PolarHBondContact O-N 3.42Å; D715-R718 WeakPolarHBondContact O-CB 3.23Å; D715-R718 PolarHBondContact O-N 2.91Å; D715-R718 IonicContact OD1-CZ 3.32Å; D715-R718 IonicContact OD1-NH1 2.8Å; D715-R718 PolarHBondContact OD1-NH1 3.44Å; E716-R718 VanDerWaalsContact C-N 3.33Å; E716-R718 PolarHBondContact O-N 2.84Å; R718-L720 VanDerWaalsContact C-N 3.34Å; R718-L720 PolarHBondContact O-N 2.99Å; R718-N721 PolarHBondContact O-N 3.11Å; R718-E722 PolarHBondContact O-N 3.45Å
719H96.7Very high93.9Very high124 Ų12464.7 Ų64.757%0.57430%0.302SS*.Hα-helixtrans-62-42.2176.4177.6-87000111.6D715 E716 N721 E722D715-H719 PolarHBondContact O-N 3.35Å; D715-H719 VanDerWaalsContact O-N 3.15Å; E716-H719 PolarHBondContact O-N 3.25Å; H719-N721 VanDerWaalsContact C-N 3.26Å; H719-N721 PolarHBondContact O-N 3.01Å; H719-E722 WeakPolarHBondContact O-CG 3.4Å; H719-E722 PolarHBondContact O-N 3.34Å
720L97.3Very high94.2Very high26 Ų2662.4 Ų62.414%0.13630%0.3CS..Hα-helixtrans-69.5-23.6177-68.5170.1000113.6E716 L717 R718 E722 N728 A730 L731 Q734E716-L720 HydrophobicContact CG-CD1 4.08Å; E716-L720 WeakPolarHBondContact O-CG 3.46Å; E716-L720 PolarHBondContact O-N 2.96Å; L717-L720 PolarHBondContact O-N 2.9Å; R718-L720 VanDerWaalsContact C-N 3.34Å; R718-L720 PolarHBondContact O-N 2.99Å; L720-E722 VanDerWaalsContact C-N 3.31Å; L720-N728 PolarHBondContact O-ND2 2.85Å; L720-A730 HydrophobicContact CD1-CB 4.33Å; L720-A730 HydrophobicContact CD2-CB 3.98Å; L720-L731 HydrophobicContact CB-CB 4.25Å; L720-L731 HydrophobicContact CB-CD1 4.03Å; L720-Q734 HydrophobicContact CD1-CB 3.66Å; L720-Q734 HydrophobicContact CD1-CG 4.02Å
721N96.6Very high94.4Very high28 Ų2862.6 Ų62.615%0.1530%0.301CS..THydrogen-bonded Turntrans-92.114.1-178.7-161.324.3000113.2N684 L717 R718 H719 L731N684-N721 WeakPolarHBondContact CB-OD1 3.41Å; N684-N721 PolarHBondContact O-ND2 3.37Å; L717-N721 VanDerWaalsContact O-CB 3.23Å; L717-N721 WeakPolarHBondContact O-CB 3.26Å; L717-N721 PolarHBondContact O-N 3.14Å; R718-N721 PolarHBondContact O-N 3.11Å; H719-N721 VanDerWaalsContact C-N 3.26Å; H719-N721 PolarHBondContact O-N 3.01Å; N721-L731 HydrophobicContact CB-CD1 3.83Å
722E95.8Very high94.7Very high95 Ų9556.8 Ų56.844%0.44428%0.276SS..  trans-59.8142.4172.3-76.4-176.6174.200111.2R718 H719 L720 Q725R718-E722 PolarHBondContact O-N 3.45Å; H719-E722 WeakPolarHBondContact O-CG 3.4Å; H719-E722 PolarHBondContact O-N 3.34Å; L720-E722 VanDerWaalsContact C-N 3.31Å; E722-Q725 HydrophobicContact CB-CG 4.07Å; E722-Q725 VanDerWaalsContact O-CG 3.26Å; E722-Q725 WeakPolarHBondContact O-CG 3.46Å
723P93.2Very high94.8Very high62 Ų6251.3 Ų51.340%0.40325%0.251SS..THydrogen-bonded Turntrans-61.2148.3-178.2-14.725.4000112.1Q725P723-Q725 VanDerWaalsContact C-N 3.28Å; P723-Q725 PolarHBondContact O-N 3.45Å
724H89.7Confident94.9Very high130 Ų13051.8 Ų51.860%0.60225%0.253SS*.THydrogen-bonded Turntrans70.915.5176.4-42.892000115.3N681 W726N681-H724 PolarHBondContact ND2-N 3.49Å; N681-H724 PolarHBondContact OD1-N 2.83Å; N681-H724 VanDerWaalsContact OD1-N 3.09Å; H724-W726 HydrophobicContact CB-CZ2 4.06Å; H724-W726 AromaticContact CD2-CZ2 3.78Å; H724-W726 PolarHBondContact O-N 2.98Å; H724-W726 PolarHBondContact O-NE1 3.24Å
725Q88.2Confident95Very high95 Ų9551 Ų5144%0.44425%0.249SC..  trans-85.481171.2-63.5-65.7-1200110.9E722 P723 N728E722-Q725 HydrophobicContact CB-CG 4.07Å; E722-Q725 VanDerWaalsContact O-CG 3.26Å; E722-Q725 WeakPolarHBondContact O-CG 3.46Å; P723-Q725 VanDerWaalsContact C-N 3.28Å; P723-Q725 PolarHBondContact O-N 3.45Å; Q725-N728 HydrophobicContact CB-CB 4.2Å; Q725-N728 WeakPolarHBondContact O-CB 3.33Å
726W88.6Confident95.1Very high67 Ų6747.8 Ų47.825%0.25423%0.231SC..THydrogen-bonded Turntrans-79.5145.2-171.2-49.7119.9000114.4I672 A677 E680 N681 H724 N728I672-W726 HydrophobicContact CD1-CB 3.41Å; I672-W726 VanDerWaalsContact CD1-CB 3.41Å; I672-W726 HydrophobicContact CD1-CD2 4.24Å; I672-W726 HydrophobicContact CD1-CG 3.53Å; I672-W726 HydrophobicContact CG1-CB 4.09Å; I672-W726 HydrophobicContact CG1-CD2 3.89Å; I672-W726 HydrophobicContact CG1-CG 3.66Å; I672-W726 HydrophobicContact CG2-CG 4.33Å; A677-W726 HydrophobicContact CB-CD2 4.26Å; A677-W726 HydrophobicContact CB-CE3 3.94Å; A677-W726 HydrophobicContact CB-CH2 3.51Å; A677-W726 HydrophobicContact CB-CZ2 3.84Å; A677-W726 HydrophobicContact CB-CZ3 3.59Å; A677-W726 VanDerWaalsContact O-CH2 3.24Å; A677-W726 WeakPolarHBondContact O-CH2 3.48Å; A677-W726 WeakPolarHBondContact O-CZ3 3.34Å; E680-W726 HydrophobicContact CB-CZ3 4.15Å; N681-W726 WeakPolarHBondContact ND2-CH2 3.32Å; H724-W726 HydrophobicContact CB-CZ2 4.06Å; H724-W726 AromaticContact CD2-CZ2 3.78Å; H724-W726 PolarHBondContact O-N 2.98Å; H724-W726 PolarHBondContact O-NE1 3.24Å; W726-N728 PolarHBondContact O-N 3.2Å; W726-N728 VanDerWaalsContact O-N 3.13Å
727K87.2Confident95Very high41 Ų4146.5 Ų46.518%0.17822%0.222CC..THydrogen-bonded Turntrans5623.6-177.9-53-170.8175.3-175.70112.7N665 S669 V729 F815 P817N665-K727 PolarHBondContact O-NZ 3.46Å; S669-K727 WeakPolarHBondContact OG-CE 3.36Å; S669-K727 PolarHBondContact OG-NZ 2.98Å; K727-V729 VanDerWaalsContact C-N 3.27Å; K727-V729 PolarHBondContact O-N 2.84Å; K727-F815 PolarHBondContact NZ-O 3.49Å; K727-P817 HydrophobicContact CB-CG 4.44Å
728N93.1Very high95Very high33 Ų3346.3 Ų46.318%0.17622%0.221CC..  trans-74.678.3179-175.910.1000110.2L720 Q725 W726 A730 L731L720-N728 PolarHBondContact O-ND2 2.85Å; Q725-N728 HydrophobicContact CB-CB 4.2Å; Q725-N728 WeakPolarHBondContact O-CB 3.33Å; W726-N728 PolarHBondContact O-N 3.2Å; W726-N728 VanDerWaalsContact O-N 3.13Å; N728-A730 PolarHBondContact O-N 3.39Å; N728-A730 WeakPolarHBondContact OD1-CB 3.39Å; N728-A730 PolarHBondContact OD1-N 3Å; N728-L731 VanDerWaalsContact O-CB 3.27Å; N728-L731 WeakPolarHBondContact O-CB 3.16Å; N728-L731 PolarHBondContact O-N 3.14Å; N728-L731 VanDerWaalsContact O-N 3.15Å
729V96.3Very high94.9Very high11 Ų1140.8 Ų40.87%0.06720%0.2CC..Hα-helixtrans-65.9-18.4178.6-65.70000112.8V662 V664 K727 L731 T732 H733 P817 Y820V662-V729 HydrophobicContact CG1-CG1 4.2Å; V664-V729 HydrophobicContact CG2-CG1 3.83Å; K727-V729 VanDerWaalsContact C-N 3.27Å; K727-V729 PolarHBondContact O-N 2.84Å; V729-L731 PolarHBondContact O-N 2.74Å; V729-T732 WeakPolarHBondContact O-CB 3.36Å; V729-T732 PolarHBondContact O-N 3.29Å; V729-T732 VanDerWaalsContact O-N 3.09Å; V729-H733 PolarHBondContact O-CD2 3Å; V729-H733 PolarHBondContact O-N 3.12Å; V729-P817 HydrophobicContact CG1-CG 3.86Å; V729-P817 HydrophobicContact CG2-CB 4.14Å; V729-P817 HydrophobicContact CG2-CG 4.35Å; V729-Y820 HydrophobicContact CB-CE1 4.29Å; V729-Y820 HydrophobicContact CB-CE2 4.46Å; V729-Y820 HydrophobicContact CG1-CD2 4.25Å; V729-Y820 HydrophobicContact CG1-CE1 4.47Å; V729-Y820 HydrophobicContact CG1-CE2 3.88Å; V729-Y820 HydrophobicContact CG2-CE1 4.36Å
730A97Very high94.8Very high46 Ų4637.4 Ų37.438%0.3818%0.183SC..Hα-helixtrans-61.6-34.5173.500000111.5L720 N728 T732 H733 Q734L720-A730 HydrophobicContact CD1-CB 4.33Å; L720-A730 HydrophobicContact CD2-CB 3.98Å; N728-A730 PolarHBondContact O-N 3.39Å; N728-A730 WeakPolarHBondContact OD1-CB 3.39Å; N728-A730 PolarHBondContact OD1-N 3Å; A730-T732 VanDerWaalsContact C-N 3.31Å; A730-T732 PolarHBondContact O-N 2.94Å; A730-H733 PolarHBondContact O-N 3.2Å; A730-Q734 WeakPolarHBondContact O-CB 3.38Å; A730-Q734 PolarHBondContact O-N 3Å
731L97.8Very high94.6Very high6 Ų638.5 Ų38.53%0.03119%0.188CC..Hα-helixtrans-54.4-47.8170.9177.162.9000111.4W660 V662 N684 L717 L720 N721 N728 V729 Q734 A735W660-L731 HydrophobicContact CE3-CD1 4.4Å; W660-L731 HydrophobicContact CE3-CD2 4.37Å; W660-L731 HydrophobicContact CE3-CG 4.34Å; W660-L731 HydrophobicContact CZ3-CD1 3.94Å; W660-L731 HydrophobicContact CZ3-CD2 4.45Å; W660-L731 HydrophobicContact CZ3-CG 4.35Å; V662-L731 HydrophobicContact CG2-CD2 4.45Å; N684-L731 HydrophobicContact CB-CD2 4.19Å; L717-L731 HydrophobicContact CD1-CD1 3.64Å; L717-L731 HydrophobicContact CG-CD1 4.46Å; L720-L731 HydrophobicContact CB-CB 4.25Å; L720-L731 HydrophobicContact CB-CD1 4.03Å; N721-L731 HydrophobicContact CB-CD1 3.83Å; N728-L731 VanDerWaalsContact O-CB 3.27Å; N728-L731 WeakPolarHBondContact O-CB 3.16Å; N728-L731 PolarHBondContact O-N 3.14Å; N728-L731 VanDerWaalsContact O-N 3.15Å; V729-L731 PolarHBondContact O-N 2.74Å; L731-Q734 PolarHBondContact O-N 2.86Å; L731-A735 VanDerWaalsContact O-CB 3.3Å; L731-A735 WeakPolarHBondContact O-CB 3.27Å; L731-A735 PolarHBondContact O-N 2.94Å
732T97.6Very high94.5Very high1 Ų137.1 Ų37.11%0.00618%0.18CC..Hα-helixtrans-59.5-48.9179-650000111.6H577 F579 V662 V729 A730 Q734 A735 M736H577-T732 HydrophobicContact CB-CG2 4.08Å; F579-T732 HydrophobicContact CE1-CG2 4.12Å; F579-T732 HydrophobicContact CZ-CG2 3.82Å; V662-T732 WeakPolarHBondContact CG2-OG1 3.34Å; V729-T732 WeakPolarHBondContact O-CB 3.36Å; V729-T732 PolarHBondContact O-N 3.29Å; V729-T732 VanDerWaalsContact O-N 3.09Å; A730-T732 VanDerWaalsContact C-N 3.31Å; A730-T732 PolarHBondContact O-N 2.94Å; T732-Q734 PolarHBondContact O-N 3.12Å; T732-A735 PolarHBondContact O-N 3.19Å; T732-M736 HydrophobicContact CG2-CE 3.77Å; T732-M736 HydrophobicContact CG2-SD 4.35Å; T732-M736 WeakPolarHBondContact O-CG 3.34Å; T732-M736 PolarHBondContact O-N 2.92Å
733H97.7Very high94.4Very high12 Ų1232.8 Ų32.86%0.05616%0.161CC..Hα-helixtrans-66.8-37.7-179.4-68-66.3000112.7V729 A730 M736 R737 Y763 D764 L767 Y820V729-H733 PolarHBondContact O-CD2 3Å; V729-H733 PolarHBondContact O-N 3.12Å; A730-H733 PolarHBondContact O-N 3.2Å; H733-M736 HydrophobicContact CB-CE 4.4Å; H733-M736 WeakPolarHBondContact ND1-CE 3.26Å; H733-M736 PolarHBondContact O-N 3.42Å; H733-R737 WeakPolarHBondContact O-CB 3.5Å; H733-R737 PolarHBondContact O-N 3.44Å; H733-Y763 AromaticContact CD2-CD1 3.74Å; H733-Y763 AromaticContact CD2-CE1 3.87Å; H733-Y763 AromaticContact CE1-CD1 3.62Å; H733-Y763 AromaticContact NE2-CD1 3.34Å; H733-Y763 VanDerWaalsContact NE2-CD1 3.34Å; H733-Y763 WeakPolarHBondContact NE2-CD1 3.36Å; H733-Y763 AromaticContact NE2-CE1 3.95Å; H733-D764 IonicContact CE1-OD1 3.29Å; H733-D764 IonicContact CG-OD1 3.42Å; H733-D764 IonicContact ND1-OD1 2.86Å; H733-D764 PolarHBondContact ND1-OD1 2.79Å; H733-L767 HydrophobicContact CB-CD1 4.13Å; H733-Y820 PolarHBondContact CE1-OH 3.15Å; H733-Y820 AromaticContact NE2-CE1 3.32Å; H733-Y820 VanDerWaalsContact NE2-CE1 3.32Å; H733-Y820 WeakPolarHBondContact NE2-CE1 3.26Å; H733-Y820 AromaticContact NE2-CZ 3.45Å; H733-Y820 PolarHBondContact NE2-OH 3.1Å
734Q97.7Very high94.5Very high11 Ų1129.9 Ų29.95%0.05114%0.143CC..Hα-helixtrans-68.1-40.8176-172.465.3-4.200112.1A713 E716 L717 L720 A730 L731 T732 R737 L738A713-Q734 VanDerWaalsContact CA-NE2 3.28Å; A713-Q734 PolarHBondContact O-NE2 3.06Å; E716-Q734 HydrophobicContact CG-CG 4.25Å; E716-Q734 VanDerWaalsContact OE2-CD 3.27Å; E716-Q734 PolarHBondContact OE2-NE2 3.46Å; E716-Q734 PolarHBondContact OE2-OE1 2.96Å; L717-Q734 HydrophobicContact CB-CG 4.02Å; L717-Q734 HydrophobicContact CD1-CB 4.09Å; L717-Q734 HydrophobicContact CD1-CG 3.99Å; L720-Q734 HydrophobicContact CD1-CB 3.66Å; L720-Q734 HydrophobicContact CD1-CG 4.02Å; A730-Q734 WeakPolarHBondContact O-CB 3.38Å; A730-Q734 PolarHBondContact O-N 3Å; L731-Q734 PolarHBondContact O-N 2.86Å; T732-Q734 PolarHBondContact O-N 3.12Å; Q734-R737 WeakPolarHBondContact O-CB 3.35Å; Q734-R737 PolarHBondContact O-N 2.77Å; Q734-L738 PolarHBondContact O-N 3.32Å
735A97.9Very high94.9Very high0 Ų024.3 Ų24.30%012%0.117CC..Hα-helixtrans-64.9-40.4175.600000112W660 L717 L731 T732 L738 C739W660-A735 HydrophobicContact CD2-CB 3.96Å; W660-A735 HydrophobicContact CE3-CB 4.44Å; W660-A735 HydrophobicContact CG-CB 4.36Å; W660-A735 HydrophobicContact CH2-CB 4.48Å; W660-A735 HydrophobicContact CZ2-CB 4Å; L717-A735 HydrophobicContact CD1-CB 3.83Å; L731-A735 VanDerWaalsContact O-CB 3.3Å; L731-A735 WeakPolarHBondContact O-CB 3.27Å; L731-A735 PolarHBondContact O-N 2.94Å; T732-A735 PolarHBondContact O-N 3.19Å; A735-L738 PolarHBondContact O-N 3.07Å; A735-C739 VanDerWaalsContact O-CB 3.24Å; A735-C739 WeakPolarHBondContact O-CB 3.41Å; A735-C739 PolarHBondContact O-N 3Å
736M97.8Very high95.4Very high0 Ų019.9 Ų19.90%010%0.096CC..Hα-helixtrans-62.5-43.1173.2-72.6-174.4-61.900111.9H577 T732 H733 C739 R740 V746 I748 D764H577-M736 WeakPolarHBondContact NE2-CG 3.37Å; T732-M736 HydrophobicContact CG2-CE 3.77Å; T732-M736 HydrophobicContact CG2-SD 4.35Å; T732-M736 WeakPolarHBondContact O-CG 3.34Å; T732-M736 PolarHBondContact O-N 2.92Å; H733-M736 HydrophobicContact CB-CE 4.4Å; H733-M736 WeakPolarHBondContact ND1-CE 3.26Å; H733-M736 PolarHBondContact O-N 3.42Å; M736-C739 WeakPolarHBondContact O-CB 3.26Å; M736-C739 PolarHBondContact O-N 2.91Å; M736-R740 WeakPolarHBondContact O-CG 3.38Å; M736-R740 PolarHBondContact O-N 3.46Å; M736-R740 VanDerWaalsContact O-N 3.08Å; M736-V746 HydrophobicContact CB-CG2 4.09Å; M736-V746 HydrophobicContact CG-CG1 3.79Å; M736-V746 HydrophobicContact CG-CG2 3.94Å; M736-V746 HydrophobicContact SD-CG1 3.56Å; M736-V746 VanDerWaalsContact SD-CG1 3.56Å; M736-I748 HydrophobicContact SD-CD1 3.71Å; M736-I748 HydrophobicContact SD-CG1 4.19Å; M736-D764 HydrophobicContact CE-CB 3.99Å; M736-D764 WeakPolarHBondContact CE-OD1 3.33Å
737R95.6Very high95.9Very high68 Ų6816.7 Ų16.726%0.2578%0.084SC..Hα-helixtrans-59-52.5175.4177-175.5171.7-156.1-0.2111.2E716 H733 Q734 C739 R740 M741E716-R737 IonicContact OE2-NH1 3.52Å; E716-R737 PolarHBondContact OE2-NH1 2.79Å; H733-R737 WeakPolarHBondContact O-CB 3.5Å; H733-R737 PolarHBondContact O-N 3.44Å; Q734-R737 WeakPolarHBondContact O-CB 3.35Å; Q734-R737 PolarHBondContact O-N 2.77Å; R737-C739 VanDerWaalsContact C-N 3.32Å; R737-C739 PolarHBondContact O-N 2.81Å; R737-R740 PolarHBondContact O-N 3.31Å; R737-M741 HydrophobicContact CG-SD 3.98Å; R737-M741 WeakPolarHBondContact O-CG 3.29Å; R737-M741 PolarHBondContact O-N 3.11Å
738L95.5Very high96.4Very high0 Ų014.7 Ų14.70%08%0.076CC..Hα-helixtrans-63.5-38.7-179.6-175.659.2000111.9L691 I710 A713 L714 L717 Q734 A735 R740 M741 L742L691-L738 HydrophobicContact CD2-CB 4.48Å; L691-L738 HydrophobicContact CD2-CD2 3.72Å; L691-L738 HydrophobicContact CD2-CG 4.15Å; L691-L738 HydrophobicContact CG-CD2 4.24Å; I710-L738 HydrophobicContact CG2-CD1 3.65Å; A713-L738 HydrophobicContact CB-CD1 4.17Å; L714-L738 HydrophobicContact CB-CD2 4.25Å; L714-L738 HydrophobicContact CD1-CD2 3.76Å; L717-L738 HydrophobicContact CD2-CD2 3.81Å; Q734-L738 PolarHBondContact O-N 3.32Å; A735-L738 PolarHBondContact O-N 3.07Å; L738-R740 VanDerWaalsContact C-N 3.35Å; L738-R740 PolarHBondContact O-N 3.31Å; L738-M741 PolarHBondContact O-N 2.77Å; L738-L742 HydrophobicContact CD1-CD1 4.28Å; L738-L742 HydrophobicContact CD1-CG 4.5Å; L738-L742 HydrophobicContact CG-CD1 4.14Å; L738-L742 WeakPolarHBondContact O-CG 3.32Å; L738-L742 PolarHBondContact O-N 2.96Å; L738-L742 VanDerWaalsContact O-N 3.15Å
739C96.4Very high96.7Very high0 Ų013.1 Ų13.10%07%0.067CC..Hα-helixtrans-54.6-49.8173.1-179.10000111.4L573 S575 A735 M736 R737 L742 G743 G744 D745L573-C739 HydrophobicContact CD2-CB 4.47Å; S575-C739 WeakPolarHBondContact CB-SG 3.34Å; A735-C739 VanDerWaalsContact O-CB 3.24Å; A735-C739 WeakPolarHBondContact O-CB 3.41Å; A735-C739 PolarHBondContact O-N 3Å; M736-C739 WeakPolarHBondContact O-CB 3.26Å; M736-C739 PolarHBondContact O-N 2.91Å; R737-C739 VanDerWaalsContact C-N 3.32Å; R737-C739 PolarHBondContact O-N 2.81Å; C739-L742 CarbonylContact O-C 3.54Å; C739-L742 WeakPolarHBondContact O-CA 3.24Å; C739-L742 PolarHBondContact O-N 3.23Å; C739-L742 VanDerWaalsContact O-N 3.1Å; C739-G743 PolarHBondContact O-N 2.87Å; C739-G744 WeakPolarHBondContact O-CA 3.46Å; C739-G744 PolarHBondContact O-N 3.08Å; C739-G744 VanDerWaalsContact SG-CA 3.59Å; C739-D745 PolarHBondContact SG-O 3.06Å
740R93.9Very high96.6Very high54 Ų5412.7 Ų12.720%0.2047%0.065CC..Hα-helixtrans-66.6-38.1179.4-68.2-176.5-172.3117.1-7.1113.1M310 M736 R737 L738 L742 G743 V746 D764M310-R740 PolarHBondContact SD-NH1 3.16Å; M736-R740 WeakPolarHBondContact O-CG 3.38Å; M736-R740 PolarHBondContact O-N 3.46Å; M736-R740 VanDerWaalsContact O-N 3.08Å; R737-R740 PolarHBondContact O-N 3.31Å; L738-R740 VanDerWaalsContact C-N 3.35Å; L738-R740 PolarHBondContact O-N 3.31Å; R740-L742 PolarHBondContact O-N 3.43Å; R740-G743 PolarHBondContact O-N 3.29Å; R740-V746 HydrophobicContact CG-CG2 4.5Å; R740-D764 IonicContact CZ-OD2 3.76Å; R740-D764 IonicContact NH1-OD2 2.72Å; R740-D764 PolarHBondContact NH1-OD2 3.46Å; R740-D764 IonicContact NH2-OD2 2.69Å; R740-D764 PolarHBondContact NH2-OD2 3.35Å; R740-D764 VanDerWaalsContact NH2-OD2 3.1Å
741M92.6Very high96.6Very high48 Ų4813.4 Ų13.424%0.2366%0.059CC..Hα-helixtrans-59.8-24.6173.2-68.1170.572.400112.4F705 K709 I710 A713 R737 L738F705-M741 WeakPolarHBondContact CE1-O 3.34Å; K709-M741 HydrophobicContact CB-CE 3.86Å; I710-M741 HydrophobicContact CB-CE 4.39Å; I710-M741 HydrophobicContact CG1-CB 4.45Å; I710-M741 HydrophobicContact CG1-CE 3.77Å; A713-M741 HydrophobicContact CB-CE 4.3Å; A713-M741 HydrophobicContact CB-SD 4.07Å; R737-M741 HydrophobicContact CG-SD 3.98Å; R737-M741 WeakPolarHBondContact O-CG 3.29Å; R737-M741 PolarHBondContact O-N 3.11Å; L738-M741 PolarHBondContact O-N 2.77Å
742L94.3Very high96.3Very high0 Ų014 Ų140%06%0.063CC..THydrogen-bonded Turntrans-98.119.3176.9-64.2169.3000112.8L566 L573 L691 Y694 C695 F705 I710 L738 C739 R740 G744L566-L742 WeakPolarHBondContact CD1-O 3.49Å; L573-L742 HydrophobicContact CD2-CB 4.01Å; L573-L742 HydrophobicContact CD2-CD1 4.45Å; L691-L742 HydrophobicContact CD1-CD1 3.82Å; Y694-L742 HydrophobicContact CD1-CD1 4.42Å; Y694-L742 HydrophobicContact CE1-CB 4.23Å; C695-L742 HydrophobicContact CB-CD1 4Å; C695-L742 HydrophobicContact CB-CD2 4.34Å; F705-L742 HydrophobicContact CE2-CD2 4.23Å; I710-L742 HydrophobicContact CD1-CD2 4.28Å; I710-L742 HydrophobicContact CG2-CD2 4.24Å; L738-L742 HydrophobicContact CD1-CD1 4.28Å; L738-L742 HydrophobicContact CD1-CG 4.5Å; L738-L742 HydrophobicContact CG-CD1 4.14Å; L738-L742 WeakPolarHBondContact O-CG 3.32Å; L738-L742 PolarHBondContact O-N 2.96Å; L738-L742 VanDerWaalsContact O-N 3.15Å; C739-L742 CarbonylContact O-C 3.54Å; C739-L742 WeakPolarHBondContact O-CA 3.24Å; C739-L742 PolarHBondContact O-N 3.23Å; C739-L742 VanDerWaalsContact O-N 3.1Å; R740-L742 PolarHBondContact O-N 3.43Å; L742-G744 PolarHBondContact O-N 2.76Å
743G93.8Very high96.1Very high3 Ų313.9 Ų13.93%0.0316%0.063CC..THydrogen-bonded Turntrans68.710.3-178.600000114.4K563 C739 R740K563-G743 WeakPolarHBondContact CG-O 3.18Å; K563-G743 PolarHBondContact NZ-O 3.26Å; C739-G743 PolarHBondContact O-N 2.87Å; R740-G743 PolarHBondContact O-N 3.29Å
744G96.7Very high95.8Very high2 Ų213.8 Ų13.82%0.0216%0.063CC..  trans-79168.7179.400000113.9K563 L573 C739 L742K563-G744 PolarHBondContact NZ-O 3.16Å; L573-G744 WeakPolarHBondContact O-CA 3.33Å; C739-G744 WeakPolarHBondContact O-CA 3.46Å; C739-G744 PolarHBondContact O-N 3.08Å; C739-G744 VanDerWaalsContact SG-CA 3.59Å; L742-G744 PolarHBondContact O-N 2.76Å
745D98Very high95.5Very high13 Ų1314.1 Ų14.17%0.077%0.065CC..EExtended strand (participates in β ladder)trans-117.5159.7177.2-68.6-70000111.4V547 V551 K563 L573 V574 S575 C739V547-D745 HydrophobicContact CG1-CB 3.39Å; V551-D745 WeakPolarHBondContact CG2-OD2 3.26Å; K563-D745 IonicContact NZ-OD1 3.81Å; K563-D745 PolarHBondContact NZ-OD1 2.97Å; K563-D745 IonicContact NZ-OD2 3.39Å; K563-D745 PolarHBondContact NZ-OD2 2.76Å; L573-D745 PolarHBondContact O-N 3.17Å; V574-D745 CarbonylContact C-O 3.58Å; V574-D745 WeakPolarHBondContact CA-O 3.5Å; S575-D745 PolarHBondContact N-O 3.49Å; C739-D745 PolarHBondContact SG-O 3.06Å
746V98.3Very high95.4Very high1 Ų115.3 Ų15.31%0.0067%0.069CC..EExtended strand (participates in β ladder)trans-118.1128-170.3172.20000110.7Y312 F313 S575 M736 R740 I748Y312-V746 HydrophobicContact CD1-CG1 4.39Å; F313-V746 PolarHBondContact N-O 3.14Å; S575-V746 WeakPolarHBondContact O-CA 3.45Å; M736-V746 HydrophobicContact CB-CG2 4.09Å; M736-V746 HydrophobicContact CG-CG1 3.79Å; M736-V746 HydrophobicContact CG-CG2 3.94Å; M736-V746 HydrophobicContact SD-CG1 3.56Å; M736-V746 VanDerWaalsContact SD-CG1 3.56Å; R740-V746 HydrophobicContact CG-CG2 4.5Å; V746-I748 HydrophobicContact CG1-CD1 4.14Å; V746-I748 HydrophobicContact CG1-CG1 3.65Å
747V98.5Very high95.3Very high0 Ų015.3 Ų15.30%07%0.069CC..EExtended strand (participates in β ladder)trans-114.9128.6167.7-176.60000108.1F313 V547 V574 S575 L576 H577F313-V747 HydrophobicContact CB-CB 4.45Å; F313-V747 HydrophobicContact CB-CG1 4.4Å; F313-V747 HydrophobicContact CB-CG2 4.03Å; F313-V747 CarbonylContact O-C 3.57Å; F313-V747 WeakPolarHBondContact O-CA 3.37Å; V547-V747 HydrophobicContact CG2-CG2 3.75Å; V574-V747 HydrophobicContact CG1-CG2 3.69Å; S575-V747 PolarHBondContact O-N 3.36Å; L576-V747 CarbonylContact C-O 3.17Å; L576-V747 WeakPolarHBondContact CA-O 3.29Å; L576-V747 HydrophobicContact CD1-CB 3.79Å; L576-V747 HydrophobicContact CD1-CG1 3.58Å; H577-V747 PolarHBondContact N-O 3.45Å
748I98.4Very high95.4Very high0 Ų012 Ų120%06%0.057CC..EExtended strand (participates in β ladder)trans-117.1125.1180-52.7-175.7000109Y312 F313 T314 C315 H577 F579 M736 V746 T757 A760 V761Y312-I748 HydrophobicContact CD1-CD1 3.87Å; Y312-I748 HydrophobicContact CE1-CD1 4.34Å; F313-I748 PolarHBondContact O-N 3.41Å; T314-I748 VanDerWaalsContact CA-O 3.28Å; T314-I748 WeakPolarHBondContact CA-O 3.49Å; T314-I748 HydrophobicContact CG2-CB 4.22Å; C315-I748 PolarHBondContact N-O 2.76Å; C315-I748 VanDerWaalsContact N-O 3.08Å; H577-I748 CarbonylContact O-C 3.5Å; H577-I748 WeakPolarHBondContact O-CA 3.41Å; F579-I748 HydrophobicContact CD2-CG2 3.96Å; F579-I748 HydrophobicContact CE2-CG2 3.37Å; F579-I748 HydrophobicContact CZ-CG2 4.37Å; M736-I748 HydrophobicContact SD-CD1 3.71Å; M736-I748 HydrophobicContact SD-CG1 4.19Å; V746-I748 HydrophobicContact CG1-CD1 4.14Å; V746-I748 HydrophobicContact CG1-CG1 3.65Å; I748-T757 HydrophobicContact CG2-CG2 3.92Å; I748-A760 HydrophobicContact CD1-CB 4.47Å; I748-A760 HydrophobicContact CG2-CB 4.3Å; I748-V761 HydrophobicContact CD1-CG2 3.92Å
749C97.9Very high95.4Very high0 Ų012.1 Ų12.10%06%0.057CC..EExtended strand (participates in β ladder)trans-127.5155.7179.673.40000114.1C315 L576 H577 S578 F579C315-C749 WeakPolarHBondContact O-CA 3.38Å; C315-C749 WeakPolarHBondContact O-CB 3.42Å; L576-C749 HydrophobicContact CD1-CB 4.46Å; H577-C749 PolarHBondContact O-N 2.79Å; S578-C749 CarbonylContact C-O 3.47Å; S578-C749 WeakPolarHBondContact CA-O 3.44Å; F579-C749 PolarHBondContact N-O 2.83Å
750C96Very high95.5Very high1 Ų112.1 Ų12.11%0.0076%0.057CC..EExtended strand (participates in β ladder)trans-148.9-172.4167.279.30000108.6C315 G316 A317 F579 S752 G753 R756 T757C315-C750 PolarHBondContact O-N 2.91Å; G316-C750 CarbonylContact C-O 3.32Å; G316-C750 VanDerWaalsContact CA-O 3.28Å; G316-C750 WeakPolarHBondContact CA-O 3.43Å; A317-C750 PolarHBondContact N-O 2.88Å; F579-C750 HydrophobicContact CB-CB 4.08Å; C750-S752 PolarHBondContact O-N 2.89Å; C750-G753 PolarHBondContact SG-N 2.86Å; C750-R756 HydrophobicContact CB-CB 3.93Å; C750-T757 HydrophobicContact CB-CG2 3.95Å
751K95.5Very high95.6Very high62 Ų629.5 Ų9.527%0.275%0.047SC..SBendtrans-52.4-28.8-179.6-177.5167.9179.8163.50115Y321 L580 E586 M589Y321-K751 WeakPolarHBondContact CE1-O 3.43Å; Y321-K751 PolarHBondContact OH-O 3.31Å; L580-K751 HydrophobicContact CD2-CB 4.06Å; E586-K751 HydrophobicContact CG-CD 4.21Å; E586-K751 WeakPolarHBondContact OE1-CB 3.37Å; E586-K751 WeakPolarHBondContact OE1-CD 3.37Å; M589-K751 HydrophobicContact CE-CD 4.06Å; M589-K751 HydrophobicContact CE-CG 4.05Å; M589-K751 HydrophobicContact SD-CB 4.45Å; M589-K751 HydrophobicContact SD-CG 4Å
752S92.1Very high95.9Very high17 Ų177.2 Ų7.212%0.1194%0.036CC..SBendtrans-138.93-17859.90000114.8N296 C750 K754N296-S752 WeakPolarHBondContact CB-O 3.29Å; N296-S752 PolarHBondContact ND2-O 3.06Å; C750-S752 PolarHBondContact O-N 2.89Å; S752-K754 PolarHBondContact O-N 3.45Å
753G93.4Very high96Very high0 Ų010.2 Ų10.20%05%0.048CC..SBendtrans6716.2179.500000115.5C315 C750 T757 R793 N796C315-G753 WeakPolarHBondContact O-CA 3.14Å; C750-G753 PolarHBondContact SG-N 2.86Å; G753-T757 PolarHBondContact O-OG1 2.93Å; G753-R793 PolarHBondContact O-NH2 3.34Å; G753-N796 PolarHBondContact O-ND2 3.16Å
754K92.1Very high96.2Very high10 Ų1010 Ų104%0.0435%0.046CC..SBendtrans-108.9-89.7-175.6-168.6-179.272.8-172.50112.8S752 T757 S758 R793 N800 L801S752-K754 PolarHBondContact O-N 3.45Å; K754-T757 PolarHBondContact N-OG1 3.23Å; K754-T757 PolarHBondContact O-OG1 3.42Å; K754-S758 VanDerWaalsContact O-CB 3.32Å; K754-S758 WeakPolarHBondContact O-CB 3.09Å; K754-S758 PolarHBondContact O-N 2.76Å; K754-S758 PolarHBondContact O-OG 3.44Å; K754-R793 PolarHBondContact O-NH2 3.05Å; K754-R793 VanDerWaalsContact O-NH2 3.1Å; K754-N800 HydrophobicContact CD-CB 3.44Å; K754-N800 VanDerWaalsContact CD-CB 3.44Å; K754-L801 VanDerWaalsContact NZ-CD2 3.32Å
755D91.8Very high96.2Very high18 Ų1810 Ų1010%0.0965%0.045CC..Hα-helixtrans-72-54-162.9-48.6-74.6000113T757 S758 M759 A807 F808D755-T757 PolarHBondContact O-N 3.31Å; D755-S758 WeakPolarHBondContact O-CB 3.49Å; D755-S758 PolarHBondContact O-N 2.9Å; D755-M759 WeakPolarHBondContact O-CG 3.44Å; D755-M759 PolarHBondContact O-N 3.26Å; D755-M759 VanDerWaalsContact O-N 3.11Å; D755-A807 PolarHBondContact OD1-N 2.94Å; D755-F808 HydrophobicContact CB-CD2 4.19Å; D755-F808 HydrophobicContact CB-CE1 4.47Å; D755-F808 HydrophobicContact CB-CE2 3.57Å; D755-F808 HydrophobicContact CB-CZ 3.72Å
756R94.5Very high96.1Very high24 Ų249.3 Ų9.39%0.0914%0.042CC..Hα-helixtrans-63.3-39.5179.7-70175.5-76.5-171.2-18.2112.6F579 E586 V664 C750 M759 A760 F808F579-R756 HydrophobicContact CB-CB 4.22Å; F579-R756 PolarHBondContact O-NH1 3.01Å; E586-R756 IonicContact OE1-CZ 2.71Å; E586-R756 IonicContact OE1-NH1 3.59Å; E586-R756 PolarHBondContact OE1-NH1 3.23Å; E586-R756 IonicContact OE1-NH2 3.07Å; E586-R756 PolarHBondContact OE1-NH2 3.15Å; E586-R756 IonicContact OE2-CZ 3.29Å; E586-R756 IonicContact OE2-NH1 3.62Å; E586-R756 PolarHBondContact OE2-NH1 2.89Å; E586-R756 IonicContact OE2-NH2 3.19Å; V664-R756 WeakPolarHBondContact O-CD 3.32Å; C750-R756 HydrophobicContact CB-CB 3.93Å; R756-M759 PolarHBondContact O-N 2.91Å; R756-A760 PolarHBondContact O-N 3.2Å; R756-A760 VanDerWaalsContact O-N 3.16Å; R756-F808 HydrophobicContact CG-CE1 4.49Å; R756-F808 HydrophobicContact CG-CZ 4.47Å
757T96.4Very high96Very high0 Ų010.5 Ų10.50%05%0.048CC..Hα-helixtrans-68.3-37.1176.951.40000111.2I748 C750 G753 K754 D755 M759 A760 V761 R793I748-T757 HydrophobicContact CG2-CG2 3.92Å; C750-T757 HydrophobicContact CB-CG2 3.95Å; G753-T757 PolarHBondContact O-OG1 2.93Å; K754-T757 PolarHBondContact N-OG1 3.23Å; K754-T757 PolarHBondContact O-OG1 3.42Å; D755-T757 PolarHBondContact O-N 3.31Å; T757-M759 VanDerWaalsContact C-N 3.34Å; T757-M759 PolarHBondContact O-N 3Å; T757-A760 PolarHBondContact O-N 3.38Å; T757-V761 WeakPolarHBondContact O-CG2 3.37Å; T757-V761 PolarHBondContact O-N 3.36Å; T757-R793 PolarHBondContact OG1-NH2 3.38Å; T757-R793 VanDerWaalsContact OG1-NH2 3.09Å
758S96.3Very high95.8Very high0 Ų012.3 Ų12.30%06%0.056CC..Hα-helixtrans-59.7-42.8172.7-660000112.5K754 D755 A760 T762 R793K754-S758 VanDerWaalsContact O-CB 3.32Å; K754-S758 WeakPolarHBondContact O-CB 3.09Å; K754-S758 PolarHBondContact O-N 2.76Å; K754-S758 PolarHBondContact O-OG 3.44Å; D755-S758 WeakPolarHBondContact O-CB 3.49Å; D755-S758 PolarHBondContact O-N 2.9Å; S758-A760 VanDerWaalsContact C-N 3.3Å; S758-A760 PolarHBondContact O-N 3.49Å; S758-T762 WeakPolarHBondContact O-CB 3.5Å; S758-T762 WeakPolarHBondContact O-CG2 3.49Å; S758-T762 PolarHBondContact O-N 3.5Å; S758-T762 VanDerWaalsContact O-N 3.08Å; S758-T762 PolarHBondContact O-OG1 2.99Å; S758-R793 PolarHBondContact OG-NE 2.79Å; S758-R793 PolarHBondContact OG-NH2 3.43Å
759M96.7Very high95.5Very high1 Ų112.3 Ų12.31%0.0056%0.056CC..Hα-helixtrans-65.8-36.8179.8-61.3-58.9103.400111.8D755 R756 T757 T762 Y763 R788 Y806 F808 Y820 P822D755-M759 WeakPolarHBondContact O-CG 3.44Å; D755-M759 PolarHBondContact O-N 3.26Å; D755-M759 VanDerWaalsContact O-N 3.11Å; R756-M759 PolarHBondContact O-N 2.91Å; T757-M759 VanDerWaalsContact C-N 3.34Å; T757-M759 PolarHBondContact O-N 3Å; M759-T762 PolarHBondContact O-OG1 3.39Å; M759-Y763 VanDerWaalsContact O-CB 3.26Å; M759-Y763 WeakPolarHBondContact O-CB 3.43Å; M759-Y763 PolarHBondContact O-N 3.29Å; M759-R788 PolarHBondContact O-NH2 2.94Å; M759-Y806 HydrophobicContact CE-CD1 3.7Å; M759-Y806 HydrophobicContact CE-CD2 4.12Å; M759-Y806 HydrophobicContact CE-CE1 3.52Å; M759-Y806 HydrophobicContact CE-CE2 3.96Å; M759-Y806 HydrophobicContact CE-CG 4Å; M759-F808 HydrophobicContact CG-CE2 3.97Å; M759-F808 HydrophobicContact CG-CZ 3.99Å; M759-F808 HydrophobicContact SD-CE2 4.43Å; M759-Y820 HydrophobicContact CB-CD1 4.48Å; M759-Y820 HydrophobicContact CB-CD2 4.03Å; M759-Y820 HydrophobicContact CB-CG 3.9Å; M759-Y820 WeakPolarHBondContact CG-O 3.42Å; M759-Y820 VanDerWaalsContact SD-O 3.33Å; M759-P822 HydrophobicContact CE-CB 4.38Å; M759-P822 HydrophobicContact SD-CB 4.02Å
760A97.5Very high95.4Very high0 Ų014.3 Ų14.30%07%0.065CC..Hα-helixtrans-69.8-48.5176.600000113.1F579 I748 R756 T757 S758 Y763 D764 Y820F579-A760 HydrophobicContact CD2-CB 4.4Å; F579-A760 HydrophobicContact CE2-CB 3.28Å; F579-A760 HydrophobicContact CZ-CB 3.4Å; I748-A760 HydrophobicContact CD1-CB 4.47Å; I748-A760 HydrophobicContact CG2-CB 4.3Å; R756-A760 PolarHBondContact O-N 3.2Å; R756-A760 VanDerWaalsContact O-N 3.16Å; T757-A760 PolarHBondContact O-N 3.38Å; S758-A760 VanDerWaalsContact C-N 3.3Å; S758-A760 PolarHBondContact O-N 3.49Å; A760-Y763 PolarHBondContact O-N 3.5Å; A760-D764 WeakPolarHBondContact O-CB 3.23Å; A760-D764 PolarHBondContact O-N 3.4Å; A760-Y820 VanDerWaalsContact CA-CZ 3.48Å; A760-Y820 WeakPolarHBondContact CA-OH 3.45Å; A760-Y820 HydrophobicContact CB-CE1 4.48Å; A760-Y820 HydrophobicContact CB-CE2 3.8Å; A760-Y820 VanDerWaalsContact CB-OH 3.26Å; A760-Y820 WeakPolarHBondContact CB-OH 3.41Å
761V97.5Very high95.2Very high0 Ų019.2 Ų19.20%08%0.084CC..Hα-helixtrans-58.9-56.9179168.30000110.3Q300 Y312 T314 I748 T757 Y763 D764 E765 R793Q300-V761 HydrophobicContact CB-CG1 4.49Å; Q300-V761 HydrophobicContact CG-CG1 4.5Å; Y312-V761 HydrophobicContact CD1-CG2 4.29Å; Y312-V761 HydrophobicContact CD2-CG1 4.35Å; Y312-V761 HydrophobicContact CE2-CG1 4.45Å; Y312-V761 HydrophobicContact CG-CG2 4.41Å; T314-V761 HydrophobicContact CG2-CG2 3.47Å; T314-V761 VanDerWaalsContact CG2-CG2 3.47Å; I748-V761 HydrophobicContact CD1-CG2 3.92Å; T757-V761 WeakPolarHBondContact O-CG2 3.37Å; T757-V761 PolarHBondContact O-N 3.36Å; V761-Y763 PolarHBondContact O-N 2.9Å; V761-D764 PolarHBondContact O-N 3.37Å; V761-E765 HydrophobicContact CG1-CG 4.17Å; V761-E765 WeakPolarHBondContact CG1-OE1 3.27Å; V761-E765 WeakPolarHBondContact O-CB 3.46Å; V761-E765 VanDerWaalsContact O-CG 3.26Å; V761-E765 WeakPolarHBondContact O-CG 3.38Å; V761-E765 PolarHBondContact O-N 3.35Å; V761-R793 HydrophobicContact CG1-CG 4.43Å
762T97.2Very high95Very high0 Ų019 Ų190%09%0.085CC..Hα-helixtrans-59.4-35.4-177.452.20000112.9S758 M759 A766 L784 L787 R788 R793S758-T762 WeakPolarHBondContact O-CB 3.5Å; S758-T762 WeakPolarHBondContact O-CG2 3.49Å; S758-T762 PolarHBondContact O-N 3.5Å; S758-T762 VanDerWaalsContact O-N 3.08Å; S758-T762 PolarHBondContact O-OG1 2.99Å; M759-T762 PolarHBondContact O-OG1 3.39Å; T762-A766 WeakPolarHBondContact O-CB 3.42Å; T762-A766 PolarHBondContact O-N 3.16Å; T762-A766 VanDerWaalsContact O-N 3.09Å; T762-L784 VanDerWaalsContact O-CD1 3.29Å; T762-L784 WeakPolarHBondContact O-CD1 3.33Å; T762-L787 HydrophobicContact CG2-CB 4.18Å; T762-R788 HydrophobicContact CG2-CG 4.04Å; T762-R788 PolarHBondContact OG1-NE 3.35Å; T762-R793 HydrophobicContact CG2-CB 4.36Å; T762-R793 HydrophobicContact CG2-CG 4.14Å
763Y97.9Very high95Very high62 Ų6220.3 Ų20.324%0.2439%0.088CC..Hα-helixtrans-70.8-43175.9-171.9-109.4000112.4H733 M759 A760 V761 E765 A766 L767 L784 C819 Y820H733-Y763 AromaticContact CD2-CD1 3.74Å; H733-Y763 AromaticContact CD2-CE1 3.87Å; H733-Y763 AromaticContact CE1-CD1 3.62Å; H733-Y763 AromaticContact NE2-CD1 3.34Å; H733-Y763 VanDerWaalsContact NE2-CD1 3.34Å; H733-Y763 WeakPolarHBondContact NE2-CD1 3.36Å; H733-Y763 AromaticContact NE2-CE1 3.95Å; M759-Y763 VanDerWaalsContact O-CB 3.26Å; M759-Y763 WeakPolarHBondContact O-CB 3.43Å; M759-Y763 PolarHBondContact O-N 3.29Å; A760-Y763 PolarHBondContact O-N 3.5Å; V761-Y763 PolarHBondContact O-N 2.9Å; Y763-E765 VanDerWaalsContact C-N 3.33Å; Y763-A766 PolarHBondContact O-N 3.34Å; Y763-L767 HydrophobicContact CD1-CD1 3.86Å; Y763-L767 HydrophobicContact CD1-CG 4.27Å; Y763-L767 HydrophobicContact CE1-CD1 3.5Å; Y763-L767 HydrophobicContact CE1-CD2 4.43Å; Y763-L767 HydrophobicContact CE1-CG 4.02Å; Y763-L767 WeakPolarHBondContact O-CG 3.36Å; Y763-L767 PolarHBondContact O-N 3.34Å; Y763-L784 HydrophobicContact CD2-CD1 4.42Å; Y763-L784 HydrophobicContact CD2-CD2 3.76Å; Y763-L784 HydrophobicContact CE2-CD2 4.35Å; Y763-C819 HydrophobicContact CD2-CB 3.91Å; Y763-C819 HydrophobicContact CE1-CB 4.19Å; Y763-C819 HydrophobicContact CE2-CB 3.5Å; Y763-C819 VanDerWaalsContact CE2-CB 3.5Å; Y763-C819 HydrophobicContact CG-CB 4.43Å; Y763-Y820 HydrophobicContact CD1-CE1 4.01Å; Y763-Y820 HydrophobicContact CG-CE1 4.26Å
764D97.5Very high95Very high0 Ų027.2 Ų27.20%013%0.125CC..Hα-helixtrans-67.3-34.7177.8-159.363.2000112.3Y312 H733 M736 R740 A760 V761 L767 F768Y312-D764 HydrophobicContact CE1-CB 3.95Å; Y312-D764 WeakPolarHBondContact CE1-OD2 3.14Å; Y312-D764 VanDerWaalsContact OH-C 3.25Å; Y312-D764 WeakPolarHBondContact OH-CB 3.39Å; Y312-D764 PolarHBondContact OH-OD2 3.09Å; H733-D764 IonicContact CE1-OD1 3.29Å; H733-D764 IonicContact CG-OD1 3.42Å; H733-D764 IonicContact ND1-OD1 2.86Å; H733-D764 PolarHBondContact ND1-OD1 2.79Å; M736-D764 HydrophobicContact CE-CB 3.99Å; M736-D764 WeakPolarHBondContact CE-OD1 3.33Å; R740-D764 IonicContact CZ-OD2 3.76Å; R740-D764 IonicContact NH1-OD2 2.72Å; R740-D764 PolarHBondContact NH1-OD2 3.46Å; R740-D764 IonicContact NH2-OD2 2.69Å; R740-D764 PolarHBondContact NH2-OD2 3.35Å; R740-D764 VanDerWaalsContact NH2-OD2 3.1Å; A760-D764 WeakPolarHBondContact O-CB 3.23Å; A760-D764 PolarHBondContact O-N 3.4Å; V761-D764 PolarHBondContact O-N 3.37Å; D764-L767 PolarHBondContact O-N 3.15Å; D764-F768 WeakPolarHBondContact O-CB 3.49Å; D764-F768 PolarHBondContact O-N 3.01Å
765E96Very high95.1Very high0 Ų027.1 Ų27.10%013%0.125CC..Hα-helixtrans-61-49.1171.1-70.2172.3166.900111.2V302 M310 Y312 V761 Y763 L767 F768 V769 L787V302-E765 HydrophobicContact CG2-CB 4.31Å; V302-E765 HydrophobicContact CG2-CG 3.57Å; V302-E765 WeakPolarHBondContact CG2-OE1 3.37Å; M310-E765 HydrophobicContact CE-CG 4.47Å; Y312-E765 HydrophobicContact CE2-CG 3.61Å; Y312-E765 PolarHBondContact OH-N 3.13Å; Y312-E765 VanDerWaalsContact OH-N 3.12Å; V761-E765 HydrophobicContact CG1-CG 4.17Å; V761-E765 WeakPolarHBondContact CG1-OE1 3.27Å; V761-E765 WeakPolarHBondContact O-CB 3.46Å; V761-E765 VanDerWaalsContact O-CG 3.26Å; V761-E765 WeakPolarHBondContact O-CG 3.38Å; V761-E765 PolarHBondContact O-N 3.35Å; Y763-E765 VanDerWaalsContact C-N 3.33Å; E765-L767 VanDerWaalsContact C-N 3.33Å; E765-L767 PolarHBondContact O-N 2.85Å; E765-F768 WeakPolarHBondContact O-CB 3.25Å; E765-F768 PolarHBondContact O-N 3.24Å; E765-V769 WeakPolarHBondContact O-CG2 3.35Å; E765-V769 PolarHBondContact O-N 3.42Å; E765-L787 HydrophobicContact CB-CD1 4.01Å
766A96.7Very high95.3Very high0 Ų028.6 Ų28.60%014%0.136CC..Hα-helixtrans-60.1-42.617600000111.8T762 Y763 F768 V769 Q770 T780 L784T762-A766 WeakPolarHBondContact O-CB 3.42Å; T762-A766 PolarHBondContact O-N 3.16Å; T762-A766 VanDerWaalsContact O-N 3.09Å; Y763-A766 PolarHBondContact O-N 3.34Å; A766-F768 PolarHBondContact O-N 3.01Å; A766-V769 PolarHBondContact O-N 2.96Å; A766-Q770 VanDerWaalsContact O-CB 3.25Å; A766-Q770 WeakPolarHBondContact O-CB 3.32Å; A766-Q770 PolarHBondContact O-N 3.36Å; A766-T780 HydrophobicContact CB-CG2 4.1Å; A766-L784 HydrophobicContact CB-CB 3.96Å; A766-L784 HydrophobicContact CB-CD1 4.09Å
767L95.8Very high95.4Very high26 Ų2633.2 Ų33.214%0.13616%0.162CC..Hα-helixtrans-65.1-36.4175.9-71.7-178.4000113.1H733 Y763 D764 E765 R771H733-L767 HydrophobicContact CB-CD1 4.13Å; Y763-L767 HydrophobicContact CD1-CD1 3.86Å; Y763-L767 HydrophobicContact CD1-CG 4.27Å; Y763-L767 HydrophobicContact CE1-CD1 3.5Å; Y763-L767 HydrophobicContact CE1-CD2 4.43Å; Y763-L767 HydrophobicContact CE1-CG 4.02Å; Y763-L767 WeakPolarHBondContact O-CG 3.36Å; Y763-L767 PolarHBondContact O-N 3.34Å; D764-L767 PolarHBondContact O-N 3.15Å; E765-L767 VanDerWaalsContact C-N 3.33Å; E765-L767 PolarHBondContact O-N 2.85Å; L767-R771 WeakPolarHBondContact O-CG 3.17Å; L767-R771 VanDerWaalsContact O-CZ 3.28Å; L767-R771 PolarHBondContact O-N 3.17Å; L767-R771 VanDerWaalsContact O-N 3.16Å; L767-R771 PolarHBondContact O-NH1 3.09Å
768F93.9Very high95.4Very high37 Ų3737.8 Ų37.816%0.16219%0.187CC..Hα-helixtrans-64.5-50.2175.5168.5-103.1000111.2C308 M310 D764 E765 A766 Q770 R771 L772C308-F768 HydrophobicContact CB-CZ 4.23Å; M310-F768 HydrophobicContact CB-CD1 4.43Å; M310-F768 HydrophobicContact CB-CE1 4.14Å; M310-F768 HydrophobicContact CB-CE2 4.33Å; M310-F768 HydrophobicContact CB-CZ 4.09Å; M310-F768 HydrophobicContact CE-CB 3.24Å; M310-F768 HydrophobicContact CE-CD1 3.45Å; M310-F768 VanDerWaalsContact CE-CD1 3.45Å; M310-F768 HydrophobicContact CE-CD2 3.88Å; M310-F768 HydrophobicContact CE-CE1 4.21Å; M310-F768 HydrophobicContact CE-CG 3.24Å; M310-F768 HydrophobicContact SD-CB 3.83Å; M310-F768 HydrophobicContact SD-CD1 4.21Å; M310-F768 HydrophobicContact SD-CD2 3.56Å; M310-F768 VanDerWaalsContact SD-CD2 3.56Å; M310-F768 HydrophobicContact SD-CE2 4.12Å; M310-F768 HydrophobicContact SD-CG 3.6Å; M310-F768 VanDerWaalsContact SD-CG 3.6Å; D764-F768 WeakPolarHBondContact O-CB 3.49Å; D764-F768 PolarHBondContact O-N 3.01Å; E765-F768 WeakPolarHBondContact O-CB 3.25Å; E765-F768 PolarHBondContact O-N 3.24Å; A766-F768 PolarHBondContact O-N 3.01Å; F768-Q770 VanDerWaalsContact C-N 3.32Å; F768-Q770 PolarHBondContact O-N 3.39Å; F768-R771 PolarHBondContact O-N 3.16Å; F768-L772 HydrophobicContact CE1-CD2 4.22Å; F768-L772 HydrophobicContact CZ-CD2 4.25Å; F768-L772 WeakPolarHBondContact O-CB 3.4Å; F768-L772 PolarHBondContact O-N 2.85Å
769V93.5Very high95.4Very high0 Ų037.8 Ų37.80%019%0.187CC..Hα-helixtrans-64.8-38.8178.9-179.60000110.7V203 L212 E765 A766 R771 L772 Y773 L775 L783V203-V769 HydrophobicContact CG1-CG1 3.57Å; V203-V769 HydrophobicContact CG2-CG1 4.12Å; L212-V769 HydrophobicContact CD1-CG2 3.59Å; L212-V769 HydrophobicContact CD2-CG2 4.08Å; L212-V769 HydrophobicContact CG-CG2 4.49Å; E765-V769 WeakPolarHBondContact O-CG2 3.35Å; E765-V769 PolarHBondContact O-N 3.42Å; A766-V769 PolarHBondContact O-N 2.96Å; V769-R771 VanDerWaalsContact C-N 3.33Å; V769-R771 PolarHBondContact O-N 2.75Å; V769-L772 PolarHBondContact O-N 3.22Å; V769-Y773 HydrophobicContact CG1-CD2 3.61Å; V769-Y773 HydrophobicContact CG1-CE2 3.97Å; V769-Y773 WeakPolarHBondContact O-CD2 3.05Å; V769-Y773 PolarHBondContact O-N 2.91Å; V769-L775 HydrophobicContact CG1-CD1 3.91Å; V769-L783 HydrophobicContact CB-CD2 3.68Å; V769-L783 HydrophobicContact CG1-CD2 3.56Å; V769-L783 HydrophobicContact CG2-CD2 4.12Å
770Q94.9Very high95.4Very high43 Ų4338.3 Ų38.320%0.20119%0.19CC..Hα-helixtrans-54.3-48.5173.7-179.7-176.122.100111.8A766 F768 N774 L775 T780A766-Q770 VanDerWaalsContact O-CB 3.25Å; A766-Q770 WeakPolarHBondContact O-CB 3.32Å; A766-Q770 PolarHBondContact O-N 3.36Å; F768-Q770 VanDerWaalsContact C-N 3.32Å; F768-Q770 PolarHBondContact O-N 3.39Å; Q770-N774 CarbonylContact O-C 3.47Å; Q770-N774 WeakPolarHBondContact O-CA 3.31Å; Q770-N774 PolarHBondContact O-N 2.86Å; Q770-L775 HydrophobicContact CB-CB 4.38Å; Q770-L775 HydrophobicContact CG-CB 4.23Å; Q770-L775 PolarHBondContact O-N 3.08Å; Q770-T780 HydrophobicContact CB-CG2 4.05Å; Q770-T780 WeakPolarHBondContact CB-OG1 3.34Å; Q770-T780 HydrophobicContact CG-CG2 4.4Å; Q770-T780 VanDerWaalsContact CG-OG1 3.27Å; Q770-T780 WeakPolarHBondContact CG-OG1 3.33Å
771R92.2Very high95.3Very high103 Ų10344.2 Ų44.239%0.38922%0.216SC..Hα-helixtrans-69.4-38.6179.4-72.6-175.3-63.6-90.7-1.3112.3L767 F768 V769 Y773L767-R771 WeakPolarHBondContact O-CG 3.17Å; L767-R771 VanDerWaalsContact O-CZ 3.28Å; L767-R771 PolarHBondContact O-N 3.17Å; L767-R771 VanDerWaalsContact O-N 3.16Å; L767-R771 PolarHBondContact O-NH1 3.09Å; F768-R771 PolarHBondContact O-N 3.16Å; V769-R771 VanDerWaalsContact C-N 3.33Å; V769-R771 PolarHBondContact O-N 2.75Å; R771-Y773 VanDerWaalsContact C-N 3.34Å
772L90.9Very high95.2Very high59 Ų5948.5 Ų48.531%0.30924%0.238SC..Hα-helixtrans-65.3-39.5-177.3-174.260.7000111.8C304 C308 F768 V769C304-L772 HydrophobicContact CB-CD2 4.43Å; C308-L772 HydrophobicContact CB-CD1 4.45Å; C308-L772 HydrophobicContact CB-CD2 3.6Å; F768-L772 HydrophobicContact CE1-CD2 4.22Å; F768-L772 HydrophobicContact CZ-CD2 4.25Å; F768-L772 WeakPolarHBondContact O-CB 3.4Å; F768-L772 PolarHBondContact O-N 2.85Å; V769-L772 PolarHBondContact O-N 3.22Å
773Y92.4Very high95.1Very high43 Ų4348.5 Ų48.517%0.16924%0.238CC..Hα-helixtrans-1126.9-176.2-58.8-68.6000114.7V203 T206 V210 C304 D306 V769 R771 L775V203-Y773 HydrophobicContact CG1-CD2 3.93Å; V203-Y773 HydrophobicContact CG1-CE2 4.42Å; V203-Y773 HydrophobicContact CG1-CG 4.45Å; V203-Y773 HydrophobicContact CG2-CE2 4.49Å; T206-Y773 HydrophobicContact CG2-CD1 4.02Å; T206-Y773 HydrophobicContact CG2-CD2 4.49Å; T206-Y773 HydrophobicContact CG2-CG 3.87Å; V210-Y773 HydrophobicContact CB-CE1 4.37Å; V210-Y773 HydrophobicContact CG1-CE1 4.05Å; V210-Y773 HydrophobicContact CG1-CE2 3.95Å; V210-Y773 VanDerWaalsContact CG1-OH 3.23Å; V210-Y773 WeakPolarHBondContact CG1-OH 3.29Å; V210-Y773 HydrophobicContact CG2-CD1 4.26Å; V210-Y773 HydrophobicContact CG2-CE1 3.72Å; C304-Y773 WeakPolarHBondContact CB-OH 3.26Å; C304-Y773 PolarHBondContact SG-OH 3.29Å; C304-Y773 VanDerWaalsContact SG-OH 3.37Å; D306-Y773 PolarHBondContact OD1-OH 3.27Å; D306-Y773 WeakPolarHBondContact OD2-CE1 3.5Å; D306-Y773 PolarHBondContact OD2-OH 3.36Å; V769-Y773 HydrophobicContact CG1-CD2 3.61Å; V769-Y773 HydrophobicContact CG1-CE2 3.97Å; V769-Y773 WeakPolarHBondContact O-CD2 3.05Å; V769-Y773 PolarHBondContact O-N 2.91Å; R771-Y773 VanDerWaalsContact C-N 3.34Å; Y773-L775 VanDerWaalsContact C-N 3.27Å; Y773-L775 PolarHBondContact O-N 2.8Å
774N93.2Very high95.1Very high145 Ų14546.5 Ų46.578%0.77523%0.231SC*.THydrogen-bonded Turntrans51.943.5-174.8-59-57.9000113.2Q770Q770-N774 CarbonylContact O-C 3.47Å; Q770-N774 WeakPolarHBondContact O-CA 3.31Å; Q770-N774 PolarHBondContact O-N 2.86Å
775L94.5Very high95Very high9 Ų951 Ų515%0.04725%0.252CS..  trans-61.4144.5-179.6-56.6-174.8000111.3V203 P204 E205 T206 V769 Q770 Y773 L783V203-L775 HydrophobicContact CG1-CD1 4.02Å; V203-L775 HydrophobicContact CG1-CD2 4.05Å; P204-L775 WeakPolarHBondContact O-CD2 3.32Å; E205-L775 HydrophobicContact CB-CD2 4.27Å; T206-L775 HydrophobicContact CG2-CD2 4.37Å; V769-L775 HydrophobicContact CG1-CD1 3.91Å; Q770-L775 HydrophobicContact CB-CB 4.38Å; Q770-L775 HydrophobicContact CG-CB 4.23Å; Q770-L775 PolarHBondContact O-N 3.08Å; Y773-L775 VanDerWaalsContact C-N 3.27Å; Y773-L775 PolarHBondContact O-N 2.8Å; L775-L783 HydrophobicContact CD1-CD2 4.23Å
776S96.7Very high94.9Very high48 Ų4854 Ų5434%0.33627%0.268SS..  trans-62.8164.3168.189.60000110.8E205 D778 G779 T780E205-S776 VanDerWaalsContact CD-OG 3.26Å; E205-S776 WeakPolarHBondContact OE1-CB 3.49Å; E205-S776 PolarHBondContact OE1-OG 3.27Å; E205-S776 WeakPolarHBondContact OE2-CB 3.46Å; E205-S776 PolarHBondContact OE2-N 2.97Å; E205-S776 PolarHBondContact OE2-OG 3.08Å; S776-D778 PolarHBondContact O-N 3.32Å; S776-D778 PolarHBondContact OG-N 3.21Å; S776-G779 PolarHBondContact O-N 3.41Å; S776-G779 PolarHBondContact OG-N 2.93Å; S776-T780 WeakPolarHBondContact O-CB 3.46Å; S776-T780 PolarHBondContact O-N 3.13Å; S776-T780 PolarHBondContact O-OG1 3.09Å
777L95.3Very high94.9Very high121 Ų12154 Ų5463%0.63427%0.268SS*.Hα-helixtrans-60.8-31.7174.4-68.3175.7000112.1K781L777-K781 VanDerWaalsContact O-CG 3.24Å; L777-K781 WeakPolarHBondContact O-CG 3.41Å; L777-K781 PolarHBondContact O-N 2.74Å; L777-K781 VanDerWaalsContact O-N 3.1Å
778D96.7Very high94.9Very high97 Ų9753.3 Ų53.352%0.51926%0.264SS..Hα-helixtrans-79.2-42.1-179.9-65.5-31000111.1S776 T780 K781 I782S776-D778 PolarHBondContact O-N 3.32Å; S776-D778 PolarHBondContact OG-N 3.21Å; D778-T780 VanDerWaalsContact C-N 3.26Å; D778-T780 PolarHBondContact O-N 3.36Å; D778-K781 PolarHBondContact O-N 3.29Å; D778-K781 VanDerWaalsContact O-N 3.16Å; D778-K781 IonicContact OD1-NZ 2.7Å; D778-K781 PolarHBondContact OD1-NZ 3.28Å; D778-I782 WeakPolarHBondContact O-CG1 3.38Å; D778-I782 PolarHBondContact O-N 3.37Å
779G95.8Very high94.8Very high0 Ų054.5 Ų54.50%027%0.267CS..Hα-helixtrans-56.6-41.117000000112.4P204 E205 S776 I782 L783P204-G779 WeakPolarHBondContact CG-O 3.1Å; E205-G779 WeakPolarHBondContact OE1-CA 3.37Å; E205-G779 PolarHBondContact OE1-N 3.32Å; S776-G779 PolarHBondContact O-N 3.41Å; S776-G779 PolarHBondContact OG-N 2.93Å; G779-I782 PolarHBondContact O-N 3.29Å; G779-L783 PolarHBondContact O-N 3.02Å
780T96.6Very high94.7Very high12 Ų1260.5 Ų60.57%0.07430%0.295CS..Hα-helixtrans-65.7-40.7176.4-53.80000112.4A766 Q770 S776 D778 L784A766-T780 HydrophobicContact CB-CG2 4.1Å; Q770-T780 HydrophobicContact CB-CG2 4.05Å; Q770-T780 WeakPolarHBondContact CB-OG1 3.34Å; Q770-T780 HydrophobicContact CG-CG2 4.4Å; Q770-T780 VanDerWaalsContact CG-OG1 3.27Å; Q770-T780 WeakPolarHBondContact CG-OG1 3.33Å; S776-T780 WeakPolarHBondContact O-CB 3.46Å; S776-T780 PolarHBondContact O-N 3.13Å; S776-T780 PolarHBondContact O-OG1 3.09Å; D778-T780 VanDerWaalsContact C-N 3.26Å; D778-T780 PolarHBondContact O-N 3.36Å; T780-L784 WeakPolarHBondContact O-CB 3.14Å; T780-L784 PolarHBondContact O-N 3.06Å
781K96.1Very high94.6Very high123 Ų12358.4 Ų58.454%0.53529%0.285SS..Hα-helixtrans-64.7-43.2176.2-74.1167.9-160.7157.40111.9L777 D778 L784 E785L777-K781 VanDerWaalsContact O-CG 3.24Å; L777-K781 WeakPolarHBondContact O-CG 3.41Å; L777-K781 PolarHBondContact O-N 2.74Å; L777-K781 VanDerWaalsContact O-N 3.1Å; D778-K781 PolarHBondContact O-N 3.29Å; D778-K781 VanDerWaalsContact O-N 3.16Å; D778-K781 IonicContact OD1-NZ 2.7Å; D778-K781 PolarHBondContact OD1-NZ 3.28Å; K781-L784 PolarHBondContact O-N 3.26Å; K781-E785 WeakPolarHBondContact O-CB 3.27Å; K781-E785 PolarHBondContact O-N 2.79Å
782I95.8Very high94.6Very high90 Ų9053.5 Ų53.546%0.46227%0.267SS..Hα-helixtrans-59-51.4177.6-68.5165.7000109.4P204 D778 G779 L784 E785 D786P204-I782 HydrophobicContact CG-CB 4.38Å; P204-I782 HydrophobicContact CG-CG2 4.13Å; D778-I782 WeakPolarHBondContact O-CG1 3.38Å; D778-I782 PolarHBondContact O-N 3.37Å; G779-I782 PolarHBondContact O-N 3.29Å; I782-L784 VanDerWaalsContact C-N 3.34Å; I782-L784 PolarHBondContact O-N 2.92Å; I782-E785 PolarHBondContact O-N 3.3Å; I782-E785 VanDerWaalsContact O-N 3.17Å; I782-D786 PolarHBondContact O-N 3.25Å
783L95.7Very high94.7Very high0 Ų050.7 Ų50.70%025%0.252CS..Hα-helixtrans-58.1-45.4177.5177.862.7000112.2P204 L212 V769 L775 G779 E785 D786 L787P204-L783 HydrophobicContact CG-CB 4.18Å; L212-L783 HydrophobicContact CD2-CD1 4Å; V769-L783 HydrophobicContact CB-CD2 3.68Å; V769-L783 HydrophobicContact CG1-CD2 3.56Å; V769-L783 HydrophobicContact CG2-CD2 4.12Å; L775-L783 HydrophobicContact CD1-CD2 4.23Å; G779-L783 PolarHBondContact O-N 3.02Å; L783-E785 VanDerWaalsContact C-N 3.29Å; L783-E785 PolarHBondContact O-N 3.49Å; L783-D786 PolarHBondContact O-N 2.86Å; L783-L787 HydrophobicContact CD1-CD1 4.38Å; L783-L787 HydrophobicContact CD1-CG 4.25Å; L783-L787 HydrophobicContact CG-CD1 4.1Å; L783-L787 HydrophobicContact CG-CG 4.41Å; L783-L787 VanDerWaalsContact O-CG 3.29Å; L783-L787 WeakPolarHBondContact O-CG 3.34Å; L783-L787 PolarHBondContact O-N 3.19Å
784L96.8Very high94.6Very high21 Ų2149.1 Ų49.111%0.1125%0.246CC..Hα-helixtrans-60.8-40178.4178.561.4000112.3T762 Y763 A766 T780 K781 I782 R788T762-L784 VanDerWaalsContact O-CD1 3.29Å; T762-L784 WeakPolarHBondContact O-CD1 3.33Å; Y763-L784 HydrophobicContact CD2-CD1 4.42Å; Y763-L784 HydrophobicContact CD2-CD2 3.76Å; Y763-L784 HydrophobicContact CE2-CD2 4.35Å; A766-L784 HydrophobicContact CB-CB 3.96Å; A766-L784 HydrophobicContact CB-CD1 4.09Å; T780-L784 WeakPolarHBondContact O-CB 3.14Å; T780-L784 PolarHBondContact O-N 3.06Å; K781-L784 PolarHBondContact O-N 3.26Å; I782-L784 VanDerWaalsContact C-N 3.34Å; I782-L784 PolarHBondContact O-N 2.92Å; L784-R788 HydrophobicContact CD1-CG 4.47Å; L784-R788 WeakPolarHBondContact O-CG 3.26Å; L784-R788 PolarHBondContact O-N 3.16Å; L784-R788 VanDerWaalsContact O-N 3.13Å
785E95.4Very high94.3Very high95 Ų9542.4 Ų42.444%0.44421%0.21SC..Hα-helixtrans-64.7-46176.8-175.6160.4-166.500110.7K781 I782 L783 L787 R788 R789K781-E785 WeakPolarHBondContact O-CB 3.27Å; K781-E785 PolarHBondContact O-N 2.79Å; I782-E785 PolarHBondContact O-N 3.3Å; I782-E785 VanDerWaalsContact O-N 3.17Å; L783-E785 VanDerWaalsContact C-N 3.29Å; L783-E785 PolarHBondContact O-N 3.49Å; E785-L787 PolarHBondContact O-N 3.44Å; E785-R788 PolarHBondContact O-N 3.16Å; E785-R788 VanDerWaalsContact O-N 3.16Å; E785-R789 HydrophobicContact CG-CG 4.21Å; E785-R789 WeakPolarHBondContact O-CB 3.38Å; E785-R789 VanDerWaalsContact O-CG 3.26Å; E785-R789 WeakPolarHBondContact O-CG 3.41Å; E785-R789 PolarHBondContact O-N 2.96Å; E785-R789 IonicContact OE1-CZ 3.02Å; E785-R789 IonicContact OE1-NE 3.33Å; E785-R789 PolarHBondContact OE1-NE 2.91Å; E785-R789 IonicContact OE1-NH2 3.91Å; E785-R789 PolarHBondContact OE1-NH2 3.15Å
786D94.8Very high94Very high62 Ų6242 Ų4233%0.33221%0.208SC..Hα-helixtrans-59.4-47.8176.3-70.4-18.9000112F201 I782 L783 R788 R789 E790F201-D786 HydrophobicContact CD1-CB 3.91Å; F201-D786 HydrophobicContact CE1-CB 4.09Å; F201-D786 WeakPolarHBondContact CE1-O 3.22Å; I782-D786 PolarHBondContact O-N 3.25Å; L783-D786 PolarHBondContact O-N 2.86Å; D786-R788 PolarHBondContact O-N 2.96Å; D786-R789 PolarHBondContact O-N 3.35Å; D786-E790 PolarHBondContact O-N 3.45Å
787L95.3Very high93.4Very high0 Ų039.7 Ų39.70%019%0.192CC..Hα-helixtrans-57.5-37.5176.6-71.7172.6000111.9F201 L212 T762 E765 L783 E785 G791F201-L787 HydrophobicContact CD2-CD2 3.89Å; F201-L787 HydrophobicContact CE2-CD2 3.79Å; F201-L787 HydrophobicContact CG-CD2 4.42Å; F201-L787 HydrophobicContact CZ-CD2 4.22Å; L212-L787 HydrophobicContact CD2-CD2 4.13Å; T762-L787 HydrophobicContact CG2-CB 4.18Å; E765-L787 HydrophobicContact CB-CD1 4.01Å; L783-L787 HydrophobicContact CD1-CD1 4.38Å; L783-L787 HydrophobicContact CD1-CG 4.25Å; L783-L787 HydrophobicContact CG-CD1 4.1Å; L783-L787 HydrophobicContact CG-CG 4.41Å; L783-L787 VanDerWaalsContact O-CG 3.29Å; L783-L787 WeakPolarHBondContact O-CG 3.34Å; L783-L787 PolarHBondContact O-N 3.19Å; E785-L787 PolarHBondContact O-N 3.44Å; L787-G791 WeakPolarHBondContact O-CA 3.22Å; L787-G791 PolarHBondContact O-N 3.22Å
788R95.5Very high92.8Very high12 Ų1236.3 Ų36.35%0.04517%0.172CC..Hα-helixtrans-80.4-28.3-179.8-73.4178.2175.8170.95.5113.4M759 T762 L784 E785 D786 Y806 C819 R821 P823M759-R788 PolarHBondContact O-NH2 2.94Å; T762-R788 HydrophobicContact CG2-CG 4.04Å; T762-R788 PolarHBondContact OG1-NE 3.35Å; L784-R788 HydrophobicContact CD1-CG 4.47Å; L784-R788 WeakPolarHBondContact O-CG 3.26Å; L784-R788 PolarHBondContact O-N 3.16Å; L784-R788 VanDerWaalsContact O-N 3.13Å; E785-R788 PolarHBondContact O-N 3.16Å; E785-R788 VanDerWaalsContact O-N 3.16Å; D786-R788 PolarHBondContact O-N 2.96Å; R788-Y806 WeakPolarHBondContact O-CE2 3.46Å; R788-Y806 PolarHBondContact O-OH 2.98Å; R788-C819 VanDerWaalsContact CZ-O 3.27Å; R788-C819 PolarHBondContact NH1-O 3.02Å; R788-C819 PolarHBondContact NH2-O 3.46Å; R788-R821 PolarHBondContact NH1-O 2.87Å; R788-P823 HydrophobicContact CB-CG 3.89Å
789R93.4Very high91.9Very high62 Ų6232.4 Ų32.423%0.23415%0.15CC..Hα-helixtrans-86.1-36.9-178.2-71.6-176.6174-71-1.6113.3E785 D786 L794 P823 D825 L826E785-R789 HydrophobicContact CG-CG 4.21Å; E785-R789 WeakPolarHBondContact O-CB 3.38Å; E785-R789 VanDerWaalsContact O-CG 3.26Å; E785-R789 WeakPolarHBondContact O-CG 3.41Å; E785-R789 PolarHBondContact O-N 2.96Å; E785-R789 IonicContact OE1-CZ 3.02Å; E785-R789 IonicContact OE1-NE 3.33Å; E785-R789 PolarHBondContact OE1-NE 2.91Å; E785-R789 IonicContact OE1-NH2 3.91Å; E785-R789 PolarHBondContact OE1-NH2 3.15Å; D786-R789 PolarHBondContact O-N 3.35Å; R789-L794 WeakPolarHBondContact O-CD2 3.39Å; R789-P823 HydrophobicContact CG-CB 4.44Å; R789-P823 HydrophobicContact CG-CG 4.09Å; R789-D825 IonicContact CZ-OD1 2.87Å; R789-D825 VanDerWaalsContact CZ-OD1 3.28Å; R789-D825 IonicContact CZ-OD2 2.83Å; R789-D825 IonicContact NH1-OD1 2.85Å; R789-D825 PolarHBondContact NH1-OD1 3.18Å; R789-D825 IonicContact NH1-OD2 3.28Å; R789-D825 PolarHBondContact NH1-OD2 3.48Å; R789-D825 IonicContact NH2-OD1 2.83Å; R789-D825 PolarHBondContact NH2-OD1 3.09Å; R789-L826 HydrophobicContact CB-CD1 4.09Å; R789-L826 HydrophobicContact CG-CD1 3.73Å
790E91Very high91.2Very high125 Ų12532.4 Ų32.458%0.58415%0.15SC*.Hα-helixtrans-127.7-3.1-171.4-60.1-61.8155.500113.2R199 F201 D786R199-E790 VanDerWaalsContact CD-O 3.3Å; R199-E790 WeakPolarHBondContact CD-O 3.35Å; R199-E790 WeakPolarHBondContact CG-O 3.29Å; R199-E790 PolarHBondContact NE-O 2.96Å; F201-E790 HydrophobicContact CE1-CB 4Å; F201-E790 HydrophobicContact CZ-CB 4.35Å; D786-E790 PolarHBondContact O-N 3.45Å
791G91.8Very high90.2Very high0 Ų035 Ų350%016%0.163CC..SBendtrans-75.7171.3-177.500000115.7E214 L787 R793 L794E214-G791 WeakPolarHBondContact OE2-CA 3.22Å; L787-G791 WeakPolarHBondContact O-CA 3.22Å; L787-G791 PolarHBondContact O-N 3.22Å; G791-R793 PolarHBondContact O-N 3.35Å; G791-L794 WeakPolarHBondContact O-CB 3.42Å; G791-L794 PolarHBondContact O-N 3.41Å; G791-L794 VanDerWaalsContact O-N 3.14Å
792T92.2Very high89.2Confident0 Ų031.3 Ų31.30%016%0.159CC..Hα-helixtrans-63.8-28.8-17475.70000112I197 R199 E214 M216 L794 E795 N796I197-T792 HydrophobicContact CG2-CG2 4.16Å; R199-T792 HydrophobicContact CB-CG2 4.12Å; R199-T792 HydrophobicContact CG-CG2 3.84Å; E214-T792 HydrophobicContact CB-CG2 4.05Å; E214-T792 HydrophobicContact CG-CG2 3.7Å; E214-T792 WeakPolarHBondContact O-CG2 3.26Å; E214-T792 WeakPolarHBondContact OE1-CB 3.22Å; E214-T792 PolarHBondContact OE1-N 2.92Å; E214-T792 PolarHBondContact OE1-OG1 2.79Å; E214-T792 PolarHBondContact OE2-N 2.92Å; M216-T792 HydrophobicContact CB-CG2 4.08Å; M216-T792 WeakPolarHBondContact CB-OG1 3.18Å; M216-T792 VanDerWaalsContact CE-O 3.23Å; M216-T792 WeakPolarHBondContact CE-O 3.5Å; T792-L794 PolarHBondContact O-N 2.78Å; T792-E795 WeakPolarHBondContact O-CA 3.41Å; T792-E795 VanDerWaalsContact O-CB 3.32Å; T792-E795 WeakPolarHBondContact O-CB 3.41Å; T792-E795 PolarHBondContact O-N 2.89Å; T792-N796 PolarHBondContact O-N 3.13Å
793R93.7Very high88.3Confident0 Ų027.7 Ų27.70%014%0.143CC..Hα-helixtrans-64.9-21.9178.3-67.5-51.8-56-177.2-7.4113.6T314 G753 K754 T757 S758 V761 T762 G791 N796 A797T314-R793 PolarHBondContact OG1-NH1 2.98Å; G753-R793 PolarHBondContact O-NH2 3.34Å; K754-R793 PolarHBondContact O-NH2 3.05Å; K754-R793 VanDerWaalsContact O-NH2 3.1Å; T757-R793 PolarHBondContact OG1-NH2 3.38Å; T757-R793 VanDerWaalsContact OG1-NH2 3.09Å; S758-R793 PolarHBondContact OG-NE 2.79Å; S758-R793 PolarHBondContact OG-NH2 3.43Å; V761-R793 HydrophobicContact CG1-CG 4.43Å; T762-R793 HydrophobicContact CG2-CB 4.36Å; T762-R793 HydrophobicContact CG2-CG 4.14Å; G791-R793 PolarHBondContact O-N 3.35Å; R793-N796 VanDerWaalsContact CZ-ND2 3.32Å; R793-N796 PolarHBondContact NH1-ND2 2.92Å; R793-N796 PolarHBondContact NH2-ND2 2.96Å; R793-N796 WeakPolarHBondContact O-CB 3.24Å; R793-N796 PolarHBondContact O-N 3.13Å; R793-A797 PolarHBondContact O-N 3.21Å
794L90Very high87.8Confident9 Ų931.5 Ų31.55%0.04716%0.157CC..Hα-helixtrans-74.1-31.3171.4-164.563.6000112R789 G791 T792 N796 A797 Y798 R804 Y806R789-L794 WeakPolarHBondContact O-CD2 3.39Å; G791-L794 WeakPolarHBondContact O-CB 3.42Å; G791-L794 PolarHBondContact O-N 3.41Å; G791-L794 VanDerWaalsContact O-N 3.14Å; T792-L794 PolarHBondContact O-N 2.78Å; L794-N796 VanDerWaalsContact C-N 3.33Å; L794-A797 WeakPolarHBondContact O-CB 3.26Å; L794-A797 PolarHBondContact O-N 2.8Å; L794-Y798 PolarHBondContact O-N 2.97Å; L794-R804 VanDerWaalsContact CD1-C 3.46Å; L794-R804 HydrophobicContact CD1-CB 4.19Å; L794-R804 WeakPolarHBondContact CD1-O 3.11Å; L794-R804 HydrophobicContact CD2-CB 3.84Å; L794-R804 HydrophobicContact CD2-CG 4.35Å; L794-R804 HydrophobicContact CG-CB 3.68Å; L794-R804 HydrophobicContact CG-CG 4.08Å; L794-Y806 HydrophobicContact CD1-CD2 4.41Å; L794-Y806 HydrophobicContact CD1-CE1 4.42Å; L794-Y806 HydrophobicContact CD1-CE2 3.9Å
795E86.4Confident87.3Confident4 Ų434.2 Ų34.22%0.01917%0.166CC..Hα-helixtrans-68.5-32.5171.6-60.5-61152.200111.7I197 R199 M216 T792 A797 Y798 K799 R804I197-E795 HydrophobicContact CD1-CB 3.87Å; I197-E795 HydrophobicContact CD1-CG 4.26Å; I197-E795 HydrophobicContact CG2-CG 4.24Å; R199-E795 IonicContact CZ-OE1 2.9Å; R199-E795 IonicContact NH2-OE1 3.84Å; R199-E795 PolarHBondContact NH2-OE1 2.84Å; M216-E795 HydrophobicContact CE-CB 4.22Å; T792-E795 WeakPolarHBondContact O-CA 3.41Å; T792-E795 VanDerWaalsContact O-CB 3.32Å; T792-E795 WeakPolarHBondContact O-CB 3.41Å; T792-E795 PolarHBondContact O-N 2.89Å; E795-A797 VanDerWaalsContact C-N 3.29Å; E795-A797 PolarHBondContact O-N 3.45Å; E795-Y798 WeakPolarHBondContact O-CB 3.32Å; E795-Y798 PolarHBondContact O-N 3.18Å; E795-K799 WeakPolarHBondContact O-CG 3.37Å; E795-K799 PolarHBondContact O-N 3.4Å; E795-R804 IonicContact OE1-CZ 3.5Å; E795-R804 IonicContact OE1-NE 2.76Å; E795-R804 PolarHBondContact OE1-NE 3.04Å; E795-R804 IonicContact OE1-NH2 3.73Å; E795-R804 PolarHBondContact OE1-NH2 3.31Å; E795-R804 VanDerWaalsContact OE1-NH2 3.13Å; E795-R804 IonicContact OE2-CZ 3.15Å; E795-R804 IonicContact OE2-NE 3.79Å; E795-R804 PolarHBondContact OE2-NE 3.3Å; E795-R804 IonicContact OE2-NH2 3.77Å; E795-R804 PolarHBondContact OE2-NH2 2.77Å
796N88Confident87.1Confident0 Ų029.7 Ų29.70%015%0.145CC..Hα-helixtrans-61.7-40.4170.6-175.724.3000111.1M216 H298 G753 T792 R793 L794 Y798 K799 N800M216-N796 HydrophobicContact CE-CB 4.16Å; M216-N796 HydrophobicContact SD-CB 4.16Å; H298-N796 PolarHBondContact NE2-OD1 2.95Å; G753-N796 PolarHBondContact O-ND2 3.16Å; T792-N796 PolarHBondContact O-N 3.13Å; R793-N796 VanDerWaalsContact CZ-ND2 3.32Å; R793-N796 PolarHBondContact NH1-ND2 2.92Å; R793-N796 PolarHBondContact NH2-ND2 2.96Å; R793-N796 WeakPolarHBondContact O-CB 3.24Å; R793-N796 PolarHBondContact O-N 3.13Å; L794-N796 VanDerWaalsContact C-N 3.33Å; N796-Y798 VanDerWaalsContact C-N 3.34Å; N796-Y798 PolarHBondContact O-N 3.36Å; N796-K799 PolarHBondContact O-N 2.88Å; N796-N800 WeakPolarHBondContact O-CB 3.27Å; N796-N800 PolarHBondContact O-N 3.16Å; N796-N800 PolarHBondContact O-ND2 3.1Å; N796-N800 PolarHBondContact OD1-ND2 3.17Å
797A84.9Confident86.6Confident0 Ų028.7 Ų28.70%015%0.145CC..Hα-helixtrans-61.5-43.8173.500000111.7R793 L794 E795 N800 L801 A803 R805R793-A797 PolarHBondContact O-N 3.21Å; L794-A797 WeakPolarHBondContact O-CB 3.26Å; L794-A797 PolarHBondContact O-N 2.8Å; E795-A797 VanDerWaalsContact C-N 3.29Å; E795-A797 PolarHBondContact O-N 3.45Å; A797-N800 PolarHBondContact O-N 2.81Å; A797-L801 WeakPolarHBondContact O-CB 3.49Å; A797-L801 PolarHBondContact O-N 2.99Å; A797-A803 CarbonylContact C-O 3.41Å; A797-R805 WeakPolarHBondContact CB-O 3.42Å
798Y83.7Confident86.2Confident51 Ų5129.3 Ų29.320%0.215%0.148CC..Hα-helixtrans-59.7-49.7176-177.6-107000112.9G159 F160 L794 E795 N796 N800 L801 G802 A803 R804G159-Y798 PolarHBondContact O-OH 2.88Å; F160-Y798 HydrophobicContact CD2-CE1 4.36Å; L794-Y798 PolarHBondContact O-N 2.97Å; E795-Y798 WeakPolarHBondContact O-CB 3.32Å; E795-Y798 PolarHBondContact O-N 3.18Å; N796-Y798 VanDerWaalsContact C-N 3.34Å; N796-Y798 PolarHBondContact O-N 3.36Å; Y798-N800 PolarHBondContact O-N 2.86Å; Y798-N800 VanDerWaalsContact O-N 3.16Å; Y798-L801 PolarHBondContact O-N 3.12Å; Y798-G802 VanDerWaalsContact CD2-C 3.42Å; Y798-G802 WeakPolarHBondContact CD2-O 3.41Å; Y798-G802 WeakPolarHBondContact CE2-O 3.34Å; Y798-G802 VanDerWaalsContact O-CA 3.25Å; Y798-G802 WeakPolarHBondContact O-CA 3.5Å; Y798-G802 PolarHBondContact O-N 3.32Å; Y798-A803 VanDerWaalsContact CA-O 3.31Å; Y798-A803 WeakPolarHBondContact CA-O 3.47Å; Y798-A803 PolarHBondContact N-O 3.12Å; Y798-R804 HydrophobicContact CD2-CG 4.19Å; Y798-R804 HydrophobicContact CG-CG 4.24Å
799K77.8Confident85.8Confident14 Ų1434.1 Ų34.16%0.06117%0.169CC..Hα-helixtrans-55.3-35.6176.7-72.2177.9-179.2-175.50112.7F160 E218 F279 E795 N796F160-K799 HydrophobicContact CD2-CG 4.21Å; F160-K799 HydrophobicContact CE2-CG 4Å; E218-K799 IonicContact OE1-NZ 2.78Å; E218-K799 PolarHBondContact OE1-NZ 3.48Å; F279-K799 HydrophobicContact CE1-CB 4.16Å; F279-K799 HydrophobicContact CZ-CB 4.23Å; F279-K799 HydrophobicContact CZ-CD 4.43Å; E795-K799 WeakPolarHBondContact O-CG 3.37Å; E795-K799 PolarHBondContact O-N 3.4Å; N796-K799 PolarHBondContact O-N 2.88Å
800N80.4Confident85.5Confident0 Ų040.7 Ų40.70%019%0.194CC..Hα-helixtrans-86.8-25.3-177.1-83.2-88.9000115.1S282 L283 N296 K754 N796 A797 Y798S282-N800 WeakPolarHBondContact CA-OD1 3.44Å; S282-N800 WeakPolarHBondContact CB-OD1 3.15Å; S282-N800 PolarHBondContact N-OD1 3.16Å; S282-N800 PolarHBondContact OG-OD1 3.17Å; L283-N800 WeakPolarHBondContact CD1-O 3.46Å; L283-N800 WeakPolarHBondContact CG-O 3.45Å; N296-N800 PolarHBondContact ND2-ND2 2.98Å; N296-N800 PolarHBondContact ND2-OD1 3.25Å; N296-N800 PolarHBondContact OD1-ND2 3.35Å; N296-N800 PolarHBondContact OD1-OD1 3.24Å; N296-N800 VanDerWaalsContact OD1-OD1 3.13Å; K754-N800 HydrophobicContact CD-CB 3.44Å; K754-N800 VanDerWaalsContact CD-CB 3.44Å; N796-N800 WeakPolarHBondContact O-CB 3.27Å; N796-N800 PolarHBondContact O-N 3.16Å; N796-N800 PolarHBondContact O-ND2 3.1Å; N796-N800 PolarHBondContact OD1-ND2 3.17Å; A797-N800 PolarHBondContact O-N 2.81Å; Y798-N800 PolarHBondContact O-N 2.86Å; Y798-N800 VanDerWaalsContact O-N 3.16Å
801L74.8Confident85.3Confident68 Ų6843.5 Ų43.536%0.35620%0.199SC..Hα-helixtrans-125.7-11.2-169.6-62.9173.3000113.5K754 A797 Y798 A803 R805 A807K754-L801 VanDerWaalsContact NZ-CD2 3.32Å; A797-L801 WeakPolarHBondContact O-CB 3.49Å; A797-L801 PolarHBondContact O-N 2.99Å; Y798-L801 PolarHBondContact O-N 3.12Å; L801-A803 PolarHBondContact O-N 3.16Å; L801-R805 WeakPolarHBondContact CD1-O 3.45Å; L801-A807 HydrophobicContact CD1-CB 3.97Å
802G74.8Confident85.1Confident44 Ų4445.4 Ų45.445%0.45421%0.208SC..SBendtrans719-164.900000113.7Y798Y798-G802 VanDerWaalsContact CD2-C 3.42Å; Y798-G802 WeakPolarHBondContact CD2-O 3.41Å; Y798-G802 WeakPolarHBondContact CE2-O 3.34Å; Y798-G802 VanDerWaalsContact O-CA 3.25Å; Y798-G802 WeakPolarHBondContact O-CA 3.5Å; Y798-G802 PolarHBondContact O-N 3.32Å
803A78.2Confident85Confident14 Ų1446.3 Ų46.312%0.11621%0.213CC..SBendtrans-145.1141.9179.100000113.7A797 Y798 L801 R805 L830A797-A803 CarbonylContact C-O 3.41Å; Y798-A803 VanDerWaalsContact CA-O 3.31Å; Y798-A803 WeakPolarHBondContact CA-O 3.47Å; Y798-A803 PolarHBondContact N-O 3.12Å; L801-A803 PolarHBondContact O-N 3.16Å; A803-R805 PolarHBondContact O-N 3.17Å; A803-L830 HydrophobicContact CB-CD1 3.69Å; A803-L830 HydrophobicContact CB-CD2 4.35Å; A803-L830 HydrophobicContact CB-CG 4.25Å
804R84.7Confident84.8Confident81 Ų8150.6 Ų50.631%0.30624%0.241SC..SBendtrans-75.462175.7-74.4-173.8-175.685.613.2111L794 E795 Y798L794-R804 VanDerWaalsContact CD1-C 3.46Å; L794-R804 HydrophobicContact CD1-CB 4.19Å; L794-R804 WeakPolarHBondContact CD1-O 3.11Å; L794-R804 HydrophobicContact CD2-CB 3.84Å; L794-R804 HydrophobicContact CD2-CG 4.35Å; L794-R804 HydrophobicContact CG-CB 3.68Å; L794-R804 HydrophobicContact CG-CG 4.08Å; E795-R804 IonicContact OE1-CZ 3.5Å; E795-R804 IonicContact OE1-NE 2.76Å; E795-R804 PolarHBondContact OE1-NE 3.04Å; E795-R804 IonicContact OE1-NH2 3.73Å; E795-R804 PolarHBondContact OE1-NH2 3.31Å; E795-R804 VanDerWaalsContact OE1-NH2 3.13Å; E795-R804 IonicContact OE2-CZ 3.15Å; E795-R804 IonicContact OE2-NE 3.79Å; E795-R804 PolarHBondContact OE2-NE 3.3Å; E795-R804 IonicContact OE2-NH2 3.77Å; E795-R804 PolarHBondContact OE2-NH2 2.77Å; Y798-R804 HydrophobicContact CD2-CG 4.19Å; Y798-R804 HydrophobicContact CG-CG 4.24Å
805R86.6Confident84.8Confident77 Ų7754 Ų5429%0.29126%0.255SS..SBendtrans-144.3138177.7-65.4-17675.3152.52.8110.9A797 L801 A803 D825 L826 Y827A797-R805 WeakPolarHBondContact CB-O 3.42Å; L801-R805 WeakPolarHBondContact CD1-O 3.45Å; A803-R805 PolarHBondContact O-N 3.17Å; R805-D825 PolarHBondContact NH2-O 3.02Å; R805-L826 CarbonylContact C-O 3.59Å; R805-L826 WeakPolarHBondContact CA-O 3.42Å; R805-Y827 PolarHBondContact NH2-O 2.93Å
806Y90.6Very high85.1Confident0 Ų054 Ų540%026%0.256CS..BIsolated β-bridgetrans-72.2136.2173.8-56.9-71.7000110.8M759 R788 L794 F808 P822 L826 Y827 G828M759-Y806 HydrophobicContact CE-CD1 3.7Å; M759-Y806 HydrophobicContact CE-CD2 4.12Å; M759-Y806 HydrophobicContact CE-CE1 3.52Å; M759-Y806 HydrophobicContact CE-CE2 3.96Å; M759-Y806 HydrophobicContact CE-CG 4Å; R788-Y806 WeakPolarHBondContact O-CE2 3.46Å; R788-Y806 PolarHBondContact O-OH 2.98Å; L794-Y806 HydrophobicContact CD1-CD2 4.41Å; L794-Y806 HydrophobicContact CD1-CE1 4.42Å; L794-Y806 HydrophobicContact CD1-CE2 3.9Å; Y806-F808 PolarHBondContact O-N 2.87Å; Y806-P822 HydrophobicContact CD2-CB 3.77Å; Y806-P822 HydrophobicContact CG-CB 4.21Å; Y806-L826 HydrophobicContact CD2-CB 4.25Å; Y806-L826 HydrophobicContact CE2-CB 4.48Å; Y806-L826 PolarHBondContact N-O 2.96Å; Y806-Y827 VanDerWaalsContact O-CA 3.22Å; Y806-Y827 WeakPolarHBondContact O-CA 3.47Å; Y806-Y827 WeakPolarHBondContact O-CB 3.37Å; Y806-G828 PolarHBondContact O-N 3.19Å
807A85.1Confident85.3Confident41 Ų4154.7 Ų54.734%0.33926%0.26SS..  trans-83.241-174.600000113.7D755 L801D755-A807 PolarHBondContact OD1-N 2.94Å; L801-A807 HydrophobicContact CD1-CB 3.97Å
808F87.2Confident85.7Confident14 Ų1459.3 Ų59.36%0.06129%0.29CS..  trans-88.3128.8169.3-64.7-84.1000110.1D755 R756 M759 Y806 I813 V816 P822 Y827 G828D755-F808 HydrophobicContact CB-CD2 4.19Å; D755-F808 HydrophobicContact CB-CE1 4.47Å; D755-F808 HydrophobicContact CB-CE2 3.57Å; D755-F808 HydrophobicContact CB-CZ 3.72Å; R756-F808 HydrophobicContact CG-CE1 4.49Å; R756-F808 HydrophobicContact CG-CZ 4.47Å; M759-F808 HydrophobicContact CG-CE2 3.97Å; M759-F808 HydrophobicContact CG-CZ 3.99Å; M759-F808 HydrophobicContact SD-CE2 4.43Å; Y806-F808 PolarHBondContact O-N 2.87Å; F808-I813 HydrophobicContact CB-CD1 3.67Å; F808-I813 HydrophobicContact CG-CD1 4.26Å; F808-V816 HydrophobicContact CD1-CG2 4.19Å; F808-V816 HydrophobicContact CE1-CG2 3.94Å; F808-P822 HydrophobicContact CB-CG 4.34Å; F808-P822 HydrophobicContact CD2-CB 4.25Å; F808-P822 HydrophobicContact CD2-CG 3.59Å; F808-P822 HydrophobicContact CE2-CG 4.12Å; F808-P822 HydrophobicContact CG-CG 4.16Å; F808-Y827 HydrophobicContact CB-CG 4.46Å; F808-Y827 WeakPolarHBondContact O-CD2 3.32Å; F808-G828 WeakPolarHBondContact O-CA 3.42Å; F808-G828 PolarHBondContact O-N 2.58Å; F808-G828 VanDerWaalsContact O-N 3.16Å
809K86Confident86.2Confident112 Ų11258.4 Ų58.449%0.48729%0.291SS..  trans-76.8146.1167.5-60.9-179-179.9-179.90108.7R811 Q812K809-R811 HydrophobicContact CB-CG 4.09Å; K809-R811 PolarHBondContact O-N 3.2Å; K809-R811 VanDerWaalsContact O-N 3.09Å; K809-Q812 HydrophobicContact CB-CG 4.15Å; K809-Q812 WeakPolarHBondContact O-CA 3.46Å; K809-Q812 VanDerWaalsContact O-CB 3.32Å; K809-Q812 WeakPolarHBondContact O-CB 3.49Å; K809-Q812 PolarHBondContact O-N 3.39Å
810R86.9Confident87Confident201 Ų20157.8 Ų57.876%0.75829%0.288SS*.G310 helixtrans-51.4-38.8178.6-166.8171.2-175.1156.93.4113.4Q812 I813 Y827R810-Q812 PolarHBondContact O-N 3.26Å; R810-I813 PolarHBondContact O-N 2.87Å; R810-Y827 HydrophobicContact CB-CE2 4.16Å; R810-Y827 HydrophobicContact CG-CE2 4.34Å
811R86.9Confident87.7Confident183 Ų18362.7 Ų62.769%0.69131%0.307SS*.G310 helixtrans-66.4-17.5175.464.8178.6178.1-120.911.3115.3K809 F815K809-R811 HydrophobicContact CB-CG 4.09Å; K809-R811 PolarHBondContact O-N 3.2Å; K809-R811 VanDerWaalsContact O-N 3.09Å; R811-F815 WeakPolarHBondContact O-CD2 3.31Å; R811-F815 WeakPolarHBondContact O-CE2 3.32Å
812Q87.9Confident88.6Confident40 Ų4059.8 Ų59.819%0.18729%0.292CS..G310 helixtrans-87.5-24.6178.3-65.6174.1-62.100112.1K809 R810 P814 F815K809-Q812 HydrophobicContact CB-CG 4.15Å; K809-Q812 WeakPolarHBondContact O-CA 3.46Å; K809-Q812 VanDerWaalsContact O-CB 3.32Å; K809-Q812 WeakPolarHBondContact O-CB 3.49Å; K809-Q812 PolarHBondContact O-N 3.39Å; R810-Q812 PolarHBondContact O-N 3.26Å; Q812-P814 VanDerWaalsContact C-CD 3.5Å; Q812-F815 WeakPolarHBondContact O-CB 3.21Å; Q812-F815 PolarHBondContact O-N 3.42Å
813I90.1Very high89.5Confident19 Ų1958.4 Ų58.410%0.09728%0.275CS..G310 helixtrans-55.4-42.1-175.8-58.2-63.5000113.4F808 R810 F815 V816 R821 P822 Y827F808-I813 HydrophobicContact CB-CD1 3.67Å; F808-I813 HydrophobicContact CG-CD1 4.26Å; R810-I813 PolarHBondContact O-N 2.87Å; I813-F815 PolarHBondContact O-N 2.9Å; I813-F815 VanDerWaalsContact O-N 3.14Å; I813-V816 PolarHBondContact O-N 3.08Å; I813-V816 VanDerWaalsContact O-N 3.08Å; I813-R821 HydrophobicContact CG2-CG 4.07Å; I813-P822 HydrophobicContact CD1-CG 3.8Å; I813-Y827 HydrophobicContact CD1-CD1 4.05Å; I813-Y827 HydrophobicContact CD1-CD2 4.07Å; I813-Y827 HydrophobicContact CD1-CE1 3.93Å; I813-Y827 HydrophobicContact CD1-CE2 4.04Å; I813-Y827 HydrophobicContact CD1-CG 4.1Å; I813-Y827 HydrophobicContact CG1-CD2 4.22Å; I813-Y827 HydrophobicContact CG1-CE1 4.15Å; I813-Y827 HydrophobicContact CG1-CE2 3.75Å
814P90.7Very high89.9Confident91 Ų9165.5 Ų65.559%0.59131%0.306SS*.G310 helixtrans-61.5-22.4176.8-25.136.2000114.2Q812Q812-P814 VanDerWaalsContact C-CD 3.5Å
815F89.8Confident90Very high80 Ų8065.9 Ų65.935%0.35131%0.314SS..G310 helixtrans-88-4.1179.5-59.7-84.6000113.5H666 K727 R811 Q812 I813H666-F815 HydrophobicContact CB-CB 4.27Å; H666-F815 HydrophobicContact CB-CD1 4.15Å; H666-F815 HydrophobicContact CB-CD2 3.97Å; H666-F815 HydrophobicContact CB-CE2 4.34Å; H666-F815 HydrophobicContact CB-CG 3.86Å; K727-F815 PolarHBondContact NZ-O 3.49Å; R811-F815 WeakPolarHBondContact O-CD2 3.31Å; R811-F815 WeakPolarHBondContact O-CE2 3.32Å; Q812-F815 WeakPolarHBondContact O-CB 3.21Å; Q812-F815 PolarHBondContact O-N 3.42Å; I813-F815 PolarHBondContact O-N 2.9Å; I813-F815 VanDerWaalsContact O-N 3.14Å
816V91.1Very high90.1Very high5 Ų563.5 Ų63.53%0.0331%0.307CS..SBendtrans-99.3134.7177.1-177.20000109V664 F808 I813 Y820 R821V664-V816 HydrophobicContact CG1-CG1 4.12Å; F808-V816 HydrophobicContact CD1-CG2 4.19Å; F808-V816 HydrophobicContact CE1-CG2 3.94Å; I813-V816 PolarHBondContact O-N 3.08Å; I813-V816 VanDerWaalsContact O-N 3.08Å; V816-Y820 WeakPolarHBondContact CG1-O 3.48Å; V816-R821 PolarHBondContact O-NE 3.5Å
817P92.8Very high90Very high14 Ų1464.8 Ų64.89%0.09131%0.312CS..  trans-51.1142.1174.8-27.835.2000111.6V664 K727 V729 C819 Y820 R821V664-P817 HydrophobicContact CG1-CG 4.34Å; K727-P817 HydrophobicContact CB-CG 4.44Å; V729-P817 HydrophobicContact CG1-CG 3.86Å; V729-P817 HydrophobicContact CG2-CB 4.14Å; V729-P817 HydrophobicContact CG2-CG 4.35Å; P817-C819 VanDerWaalsContact C-N 3.28Å; P817-C819 PolarHBondContact O-N 2.8Å; P817-Y820 WeakPolarHBondContact O-CA 3.36Å; P817-Y820 PolarHBondContact O-N 3.32Å; P817-R821 PolarHBondContact O-N 2.79Å
818P93.1Very high89.6Confident96 Ų9664.2 Ų64.262%0.62331%0.309SS*.G310 helixtrans-50.3-44.1-176.2-3036000114.3Y820 R821P818-Y820 PolarHBondContact O-N 3.28Å; P818-R821 PolarHBondContact O-N 2.83Å
819C94.5Very high88.4Confident33 Ų3367.1 Ų67.122%0.22333%0.332CS..G310 helixtrans-64.7-23.2178.256.20000113.9Y763 R788 P817Y763-C819 HydrophobicContact CD2-CB 3.91Å; Y763-C819 HydrophobicContact CE1-CB 4.19Å; Y763-C819 HydrophobicContact CE2-CB 3.5Å; Y763-C819 VanDerWaalsContact CE2-CB 3.5Å; Y763-C819 HydrophobicContact CG-CB 4.43Å; R788-C819 VanDerWaalsContact CZ-O 3.27Å; R788-C819 PolarHBondContact NH1-O 3.02Å; R788-C819 PolarHBondContact NH2-O 3.46Å; P817-C819 VanDerWaalsContact C-N 3.28Å; P817-C819 PolarHBondContact O-N 2.8Å
820Y95.6Very high86.8Confident1 Ų167.8 Ų67.80%0.00434%0.34CS..G310 helixtrans-96.87179.6-85.529000113F579 V664 V729 H733 M759 A760 Y763 V816 P817 P818F579-Y820 HydrophobicContact CD1-CE2 4.36Å; F579-Y820 AromaticContact CE1-CE2 3.74Å; F579-Y820 HydrophobicContact CE1-CE2 3.74Å; F579-Y820 HydrophobicContact CE2-CE2 4.46Å; F579-Y820 AromaticContact CZ-CE2 3.8Å; F579-Y820 HydrophobicContact CZ-CE2 3.8Å; F579-Y820 WeakPolarHBondContact CZ-OH 3.37Å; V664-Y820 HydrophobicContact CG1-CD2 4.21Å; V729-Y820 HydrophobicContact CB-CE1 4.29Å; V729-Y820 HydrophobicContact CB-CE2 4.46Å; V729-Y820 HydrophobicContact CG1-CD2 4.25Å; V729-Y820 HydrophobicContact CG1-CE1 4.47Å; V729-Y820 HydrophobicContact CG1-CE2 3.88Å; V729-Y820 HydrophobicContact CG2-CE1 4.36Å; H733-Y820 PolarHBondContact CE1-OH 3.15Å; H733-Y820 AromaticContact NE2-CE1 3.32Å; H733-Y820 VanDerWaalsContact NE2-CE1 3.32Å; H733-Y820 WeakPolarHBondContact NE2-CE1 3.26Å; H733-Y820 AromaticContact NE2-CZ 3.45Å; H733-Y820 PolarHBondContact NE2-OH 3.1Å; M759-Y820 HydrophobicContact CB-CD1 4.48Å; M759-Y820 HydrophobicContact CB-CD2 4.03Å; M759-Y820 HydrophobicContact CB-CG 3.9Å; M759-Y820 WeakPolarHBondContact CG-O 3.42Å; M759-Y820 VanDerWaalsContact SD-O 3.33Å; A760-Y820 VanDerWaalsContact CA-CZ 3.48Å; A760-Y820 WeakPolarHBondContact CA-OH 3.45Å; A760-Y820 HydrophobicContact CB-CE1 4.48Å; A760-Y820 HydrophobicContact CB-CE2 3.8Å; A760-Y820 VanDerWaalsContact CB-OH 3.26Å; A760-Y820 WeakPolarHBondContact CB-OH 3.41Å; Y763-Y820 HydrophobicContact CD1-CE1 4.01Å; Y763-Y820 HydrophobicContact CG-CE1 4.26Å; V816-Y820 WeakPolarHBondContact CG1-O 3.48Å; P817-Y820 WeakPolarHBondContact O-CA 3.36Å; P817-Y820 PolarHBondContact O-N 3.32Å; P818-Y820 PolarHBondContact O-N 3.28Å
821R94.4Very high84.3Confident103 Ų10366.3 Ų66.339%0.38934%0.344SS..PPolyproline II helixtrans-74.2130.6178.3-66.8179.6-176.71652.7110.3R788 I813 V816 P817 P818R788-R821 PolarHBondContact NH1-O 2.87Å; I813-R821 HydrophobicContact CG2-CG 4.07Å; V816-R821 PolarHBondContact O-NE 3.5Å; P817-R821 PolarHBondContact O-N 2.79Å; P818-R821 PolarHBondContact O-N 2.83Å
822P94.1Very high81.6Confident6 Ų667.3 Ų67.34%0.03937%0.371CS..PPolyproline II helixtrans-66158.3170.530.9-39000111.1M759 Y806 F808 I813 Y827M759-P822 HydrophobicContact CE-CB 4.38Å; M759-P822 HydrophobicContact SD-CB 4.02Å; Y806-P822 HydrophobicContact CD2-CB 3.77Å; Y806-P822 HydrophobicContact CG-CB 4.21Å; F808-P822 HydrophobicContact CB-CG 4.34Å; F808-P822 HydrophobicContact CD2-CB 4.25Å; F808-P822 HydrophobicContact CD2-CG 3.59Å; F808-P822 HydrophobicContact CE2-CG 4.12Å; F808-P822 HydrophobicContact CG-CG 4.16Å; I813-P822 HydrophobicContact CD1-CG 3.8Å; P822-Y827 HydrophobicContact CB-CD1 4.13Å; P822-Y827 HydrophobicContact CG-CD1 3.5Å; P822-Y827 VanDerWaalsContact CG-CD1 3.5Å; P822-Y827 HydrophobicContact CG-CE1 4.29Å; P822-Y827 HydrophobicContact CG-CG 3.94Å
823P93.2Very high81.2Confident16 Ų1668.7 Ų68.710%0.10438%0.38CS..PPolyproline II helixtrans-57.8142.9173.2-22.734.2000112.4R788 R789 D825 L826 Y827R788-P823 HydrophobicContact CB-CG 3.89Å; R789-P823 HydrophobicContact CG-CB 4.44Å; R789-P823 HydrophobicContact CG-CG 4.09Å; P823-D825 VanDerWaalsContact C-N 3.29Å; P823-D825 PolarHBondContact O-N 2.83Å; P823-L826 HydrophobicContact CB-CB 4.3Å; P823-L826 HydrophobicContact CB-CD1 4.23Å; P823-L826 HydrophobicContact CB-CG 4.41Å; P823-L826 HydrophobicContact CG-CD1 4.16Å; P823-L826 PolarHBondContact O-N 2.77Å; P823-Y827 WeakPolarHBondContact O-CD1 3.19Å
824E86.5Confident80.8Confident163 Ų16371.3 Ų71.376%0.76240%0.395SS*.THydrogen-bonded Turntrans-56.6-36-167.6-69.4-160.5157.700115.4Y827E824-Y827 WeakPolarHBondContact O-CE1 3.24Å
825D87Confident80.2Confident89 Ų8970.2 Ų70.248%0.47638%0.384SS..THydrogen-bonded Turntrans-86.5-12.5-178.656.1-57.5000113.6R789 R805 P823R789-D825 IonicContact CZ-OD1 2.87Å; R789-D825 VanDerWaalsContact CZ-OD1 3.28Å; R789-D825 IonicContact CZ-OD2 2.83Å; R789-D825 IonicContact NH1-OD1 2.85Å; R789-D825 PolarHBondContact NH1-OD1 3.18Å; R789-D825 IonicContact NH1-OD2 3.28Å; R789-D825 PolarHBondContact NH1-OD2 3.48Å; R789-D825 IonicContact NH2-OD1 2.83Å; R789-D825 PolarHBondContact NH2-OD1 3.09Å; R805-D825 PolarHBondContact NH2-O 3.02Å; P823-D825 VanDerWaalsContact C-N 3.29Å; P823-D825 PolarHBondContact O-N 2.83Å
826L88.8Confident79.7Confident26 Ų2669.6 Ų69.614%0.13639%0.386CS..SBendtrans-10411.4-173-68.5-177.7000114.9R789 R805 Y806 P823R789-L826 HydrophobicContact CB-CD1 4.09Å; R789-L826 HydrophobicContact CG-CD1 3.73Å; R805-L826 CarbonylContact C-O 3.59Å; R805-L826 WeakPolarHBondContact CA-O 3.42Å; Y806-L826 HydrophobicContact CD2-CB 4.25Å; Y806-L826 HydrophobicContact CE2-CB 4.48Å; Y806-L826 PolarHBondContact N-O 2.96Å; P823-L826 HydrophobicContact CB-CB 4.3Å; P823-L826 HydrophobicContact CB-CD1 4.23Å; P823-L826 HydrophobicContact CB-CG 4.41Å; P823-L826 HydrophobicContact CG-CD1 4.16Å; P823-L826 PolarHBondContact O-N 2.77Å
827Y87.6Confident79Confident28 Ų2873.7 Ų73.711%0.1141%0.408CS..BIsolated β-bridgetrans-124159171.467.6-99.4000113.3R805 Y806 F808 R810 I813 P822 P823 E824R805-Y827 PolarHBondContact NH2-O 2.93Å; Y806-Y827 VanDerWaalsContact O-CA 3.22Å; Y806-Y827 WeakPolarHBondContact O-CA 3.47Å; Y806-Y827 WeakPolarHBondContact O-CB 3.37Å; F808-Y827 HydrophobicContact CB-CG 4.46Å; F808-Y827 WeakPolarHBondContact O-CD2 3.32Å; R810-Y827 HydrophobicContact CB-CE2 4.16Å; R810-Y827 HydrophobicContact CG-CE2 4.34Å; I813-Y827 HydrophobicContact CD1-CD1 4.05Å; I813-Y827 HydrophobicContact CD1-CD2 4.07Å; I813-Y827 HydrophobicContact CD1-CE1 3.93Å; I813-Y827 HydrophobicContact CD1-CE2 4.04Å; I813-Y827 HydrophobicContact CD1-CG 4.1Å; I813-Y827 HydrophobicContact CG1-CD2 4.22Å; I813-Y827 HydrophobicContact CG1-CE1 4.15Å; I813-Y827 HydrophobicContact CG1-CE2 3.75Å; P822-Y827 HydrophobicContact CB-CD1 4.13Å; P822-Y827 HydrophobicContact CG-CD1 3.5Å; P822-Y827 VanDerWaalsContact CG-CD1 3.5Å; P822-Y827 HydrophobicContact CG-CE1 4.29Å; P822-Y827 HydrophobicContact CG-CG 3.94Å; P823-Y827 WeakPolarHBondContact O-CD1 3.19Å; E824-Y827 WeakPolarHBondContact O-CE1 3.24Å
828G78Confident78Confident28 Ų2877.7 Ų77.729%0.28943%0.429SS..SBendtrans118.9-171.6176.300000114.8Y806 F808Y806-G828 PolarHBondContact O-N 3.19Å; F808-G828 WeakPolarHBondContact O-CA 3.42Å; F808-G828 PolarHBondContact O-N 2.58Å; F808-G828 VanDerWaalsContact O-N 3.16Å
829S60.6Low77Confident76 Ų7676.4 Ų76.453%0.53142%0.415SS..  trans-87.7143.5178.3169.60000110.6M831S829-M831 WeakPolarHBondContact OG-CA 3.37Å; S829-M831 WeakPolarHBondContact OG-CB 3.43Å; S829-M831 PolarHBondContact OG-N 2.96Å; S829-M831 PolarHBondContact OG-O 2.85Å
830L52.5Low75.6Confident125 Ų12579.7 Ų79.765%0.65443%0.43SS*.SBendtrans-67.6-26.2165-77.4157.9000112.1A803 T832A803-L830 HydrophobicContact CB-CD1 3.69Å; A803-L830 HydrophobicContact CB-CD2 4.35Å; A803-L830 HydrophobicContact CB-CG 4.25Å; L830-T832 PolarHBondContact O-N 3.14Å; L830-T832 VanDerWaalsContact O-N 3.15Å
831M34.9Very low73.9Confident170 Ų17086.3 Ų86.384%0.83747%0.465SS*.  trans-81.790.3172.3-61.1-172.7177.200108.2S829S829-M831 WeakPolarHBondContact OG-CA 3.37Å; S829-M831 WeakPolarHBondContact OG-CB 3.43Å; S829-M831 PolarHBondContact OG-N 2.96Å; S829-M831 PolarHBondContact OG-O 2.85Å
832T29.7Very low72.1Confident205 Ų20584.7 Ų84.7100%1.25847%0.472SS*.  trans-81.40140.242.90000109L830L830-T832 PolarHBondContact O-N 3.14Å; L830-T832 VanDerWaalsContact O-N 3.15Å

Retrieved 832 of 832 residues in 912.5 ms (Link to these results)