A0A077ZA28_TRITR Loading...

MFS 2 domain containing protein

AlphaFold DB , UniProt , Accession A0A077ZA28, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 503 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.6	Very low	35.9	Very low	244 Å²	244	124.1 Å²	124.1	100%	1.202	66%	0.658	S	S	*	*				0	99.2	0	-71.9	172.5	173.5	0	0	105.6	D3	M1-D3 PolarHBondContact O-N 3.34Å
2	I	35	Very low	35.2	Very low	171 Å²	171	126.3 Å²	126.3	88%	0.877	66%	0.662	S	S	*	*			trans	-74.2	121.7	174.8	-65.7	171.5	0	0	0	105	S4	I2-S4 PolarHBondContact O-N 3.41Å; I2-S4 VanDerWaalsContact O-N 3.1Å
3	D	29.5	Very low	34.9	Very low	113 Å²	113	122.7 Å²	122.7	60%	0.604	65%	0.652	S	S	*	*			trans	-57.8	108.1	-172.3	-145.9	-33.8	0	0	0	109.7	M1 S5 T6	M1-D3 PolarHBondContact O-N 3.34Å; D3-S5 VanDerWaalsContact CG-OG 3.28Å; D3-S5 PolarHBondContact O-N 3.3Å; D3-S5 PolarHBondContact OD1-OG 2.66Å; D3-T6 PolarHBondContact O-OG1 3.48Å
4	S	36.5	Very low	34.9	Very low	80 Å²	80	122.7 Å²	122.7	56%	0.559	65%	0.651	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.5	-5.9	-178.7	54.1	0	0	0	0	112.8	I2 T6 E7 D8	I2-S4 PolarHBondContact O-N 3.41Å; I2-S4 VanDerWaalsContact O-N 3.1Å; S4-T6 VanDerWaalsContact C-N 3.29Å; S4-T6 PolarHBondContact O-N 3.34Å; S4-E7 PolarHBondContact O-N 3.13Å; S4-D8 PolarHBondContact O-N 3.1Å
5	S	37.5	Very low	34.4	Very low	71 Å²	71	122.1 Å²	122.1	50%	0.497	65%	0.653	S	S	.	*	H	α-helix	trans	-65.2	-27.7	179.7	55.4	0	0	0	0	113.5	D3	D3-S5 VanDerWaalsContact CG-OG 3.28Å; D3-S5 PolarHBondContact O-N 3.3Å; D3-S5 PolarHBondContact OD1-OG 2.66Å
6	T	41.5	Very low	34	Very low	102 Å²	102	119.9 Å²	119.9	63%	0.626	65%	0.65	S	S	*	*	H	α-helix	trans	-79.2	-24	175.9	36.1	0	0	0	0	114.3	D3 S4	D3-T6 PolarHBondContact O-OG1 3.48Å; S4-T6 VanDerWaalsContact C-N 3.29Å; S4-T6 PolarHBondContact O-N 3.34Å
7	E	38	Very low	34.1	Very low	141 Å²	141	119.9 Å²	119.9	66%	0.659	66%	0.655	S	S	*	*	H	α-helix	trans	-80.4	-31.9	177.3	-79.2	-173.9	153.2	0	0	112.5	S4 R11	S4-E7 PolarHBondContact O-N 3.13Å; E7-R11 PolarHBondContact O-N 3.43Å; E7-R11 VanDerWaalsContact O-N 3.12Å
8	D	33.2	Very low	33.9	Very low	92 Å²	92	120.2 Å²	120.2	49%	0.492	66%	0.661	S	S	.	*	H	α-helix	trans	-73.8	-33.4	179.7	-87.8	-21.6	0	0	0	112.9	S4 D10 R11 Q12	S4-D8 PolarHBondContact O-N 3.1Å; D8-D10 VanDerWaalsContact C-N 3.3Å; D8-D10 PolarHBondContact O-N 3.32Å; D8-R11 PolarHBondContact O-N 3.19Å; D8-Q12 WeakPolarHBondContact O-CB 2.78Å; D8-Q12 PolarHBondContact O-N 3.02Å
9	S	37.3	Very low	33.5	Very low	71 Å²	71	116.9 Å²	116.9	50%	0.497	66%	0.657	S	S	.	*	H	α-helix	trans	-59	-41.1	174.1	173.8	0	0	0	0	112.2	C13	S9-C13 PolarHBondContact O-N 3.31Å; S9-C13 PolarHBondContact O-SG 3.23Å
10	D	38.6	Very low	33.1	Very low	107 Å²	107	120.9 Å²	120.9	57%	0.572	67%	0.67	S	S	*	*	H	α-helix	trans	-78.6	-33.1	-179.8	-78.6	-10.6	0	0	0	111.8	D8 C13 I14	D8-D10 VanDerWaalsContact C-N 3.3Å; D8-D10 PolarHBondContact O-N 3.32Å; D10-C13 PolarHBondContact O-N 3.04Å; D10-I14 WeakPolarHBondContact O-CG1 3.4Å; D10-I14 PolarHBondContact O-N 2.92Å
11	R	35.2	Very low	32.8	Very low	173 Å²	173	118.3 Å²	118.3	65%	0.653	67%	0.671	S	S	*	*	H	α-helix	trans	-66.2	-39.4	172	-80.8	-177	170.2	-172.9	-1.9	112.4	E7 D8 C13 I14 V15	E7-R11 PolarHBondContact O-N 3.43Å; E7-R11 VanDerWaalsContact O-N 3.12Å; D8-R11 PolarHBondContact O-N 3.19Å; R11-C13 VanDerWaalsContact C-N 3.33Å; R11-C13 PolarHBondContact O-N 3.02Å; R11-I14 PolarHBondContact O-N 3.2Å; R11-I14 VanDerWaalsContact O-N 3.15Å; R11-V15 PolarHBondContact O-N 2.66Å; R11-V15 VanDerWaalsContact O-N 3.12Å
12	Q	27.2	Very low	32.8	Very low	151 Å²	151	115.5 Å²	115.5	71%	0.706	66%	0.655	S	S	*	*	H	α-helix	trans	-68.6	-31.1	177.3	-112.6	161.9	-4.2	0	0	112.8	D8 I14 S16	D8-Q12 WeakPolarHBondContact O-CB 2.78Å; D8-Q12 PolarHBondContact O-N 3.02Å; Q12-I14 VanDerWaalsContact C-N 3.27Å; Q12-I14 PolarHBondContact O-N 2.96Å; Q12-S16 PolarHBondContact O-N 2.99Å
13	C	31.6	Very low	32.5	Very low	79 Å²	79	114.7 Å²	114.7	53%	0.534	65%	0.652	S	S	.	*	H	α-helix	trans	-68.9	-23.5	171.7	-76.7	0	0	0	0	113.5	S9 D10 R11 S16	S9-C13 PolarHBondContact O-N 3.31Å; S9-C13 PolarHBondContact O-SG 3.23Å; D10-C13 PolarHBondContact O-N 3.04Å; R11-C13 VanDerWaalsContact C-N 3.33Å; R11-C13 PolarHBondContact O-N 3.02Å; C13-S16 PolarHBondContact O-OG 2.73Å
14	I	34.8	Very low	32.6	Very low	123 Å²	123	113.2 Å²	113.2	63%	0.631	66%	0.663	S	S	*	*	H	α-helix	trans	-90	-36.4	-177.8	-65.3	168.3	0	0	0	111.5	D10 R11 Q12 S16 V17	D10-I14 WeakPolarHBondContact O-CG1 3.4Å; D10-I14 PolarHBondContact O-N 2.92Å; R11-I14 PolarHBondContact O-N 3.2Å; R11-I14 VanDerWaalsContact O-N 3.15Å; Q12-I14 VanDerWaalsContact C-N 3.27Å; Q12-I14 PolarHBondContact O-N 2.96Å; I14-S16 VanDerWaalsContact C-N 3.33Å; I14-S16 PolarHBondContact O-N 3.38Å; I14-V17 PolarHBondContact O-N 3.17Å
15	V	28.3	Very low	32.1	Very low	113 Å²	113	118 Å²	118	69%	0.685	68%	0.677	S	S	*	*	H	α-helix	trans	-72.7	-26.3	179.3	179.5	0	0	0	0	112.1	R11 V17 V18	R11-V15 PolarHBondContact O-N 2.66Å; R11-V15 VanDerWaalsContact O-N 3.12Å; V15-V17 PolarHBondContact O-N 3.35Å; V15-V18 PolarHBondContact O-N 2.91Å
16	S	27.2	Very low	31.7	Very low	87 Å²	87	123 Å²	123	61%	0.608	69%	0.693	S	S	*	*	G	3₁₀ helix	trans	-68.9	-15	177.3	68.3	0	0	0	0	114.1	Q12 C13 I14 V18	Q12-S16 PolarHBondContact O-N 2.99Å; C13-S16 PolarHBondContact O-OG 2.73Å; I14-S16 VanDerWaalsContact C-N 3.33Å; I14-S16 PolarHBondContact O-N 3.38Å; S16-V18 VanDerWaalsContact C-N 3.34Å
17	V	36.1	Very low	31	Very low	121 Å²	121	123.8 Å²	123.8	73%	0.733	70%	0.699	S	S	*	*	G	3₁₀ helix	trans	-79.9	-15.1	-179.3	-175.8	0	0	0	0	112.7	I14 V15	I14-V17 PolarHBondContact O-N 3.17Å; V15-V17 PolarHBondContact O-N 3.35Å
18	V	30.3	Very low	30.6	Very low	125 Å²	125	125.1 Å²	125.1	76%	0.758	70%	0.703	S	S	*	*	G	3₁₀ helix	trans	-106.8	7.8	177.8	-167	0	0	0	0	111.9	V15 S16 H20	V15-V18 PolarHBondContact O-N 2.91Å; S16-V18 VanDerWaalsContact C-N 3.34Å; V18-H20 PolarHBondContact O-N 3.45Å; V18-H20 VanDerWaalsContact O-N 3.17Å
19	G	26.1	Very low	30.8	Very low	58 Å²	58	126.4 Å²	126.4	60%	0.598	72%	0.717	S	S	*	*			trans	-74.9	103.7	176.7	0	0	0	0	0	112.4	G21	G19-G21 PolarHBondContact O-N 3.39Å
20	H	25.4	Very low	30.6	Very low	196 Å²	196	130.6 Å²	130.6	91%	0.907	73%	0.728	S	S	*	*			trans	-46.9	106.4	162.5	-93.3	-87.2	0	0	0	110.9	V18	V18-H20 PolarHBondContact O-N 3.45Å; V18-H20 VanDerWaalsContact O-N 3.17Å
21	G	26.8	Very low	30.6	Very low	67 Å²	67	134.7 Å²	134.7	69%	0.691	74%	0.744	S	S	*	*			trans	-120.5	92.5	171.7	0	0	0	0	0	109.7	G19 N23	G19-G21 PolarHBondContact O-N 3.39Å; G21-N23 PolarHBondContact O-N 3.08Å
22	E	33.3	Very low	31	Very low	184 Å²	184	130.5 Å²	130.5	86%	0.86	75%	0.746	S	S	*	*			trans	-56.4	102.8	158.6	-68.1	176.6	149.2	0	0	107.9
23	N	29.2	Very low	32.4	Very low	155 Å²	155	128.5 Å²	128.5	83%	0.829	74%	0.744	S	S	*	*			trans	175.9	114.2	143.6	-84.4	-27.4	0	0	0	107.9	G21 E25	G21-N23 PolarHBondContact O-N 3.08Å; N23-E25 PolarHBondContact O-N 3.09Å; N23-E25 VanDerWaalsContact O-N 3.07Å
24	G	30.2	Very low	34.2	Very low	81 Å²	81	126.8 Å²	126.8	84%	0.835	74%	0.741	S	S	*	*	S	Bend	trans	-60.3	108.9	179.6	0	0	0	0	0	111.4
25	E	27	Very low	36.3	Very low	182 Å²	182	121.7 Å²	121.7	85%	0.85	71%	0.714	S	S	*	*			trans	179.2	78.7	143.6	-99.7	167.2	-170.8	0	0	105.9	N23 P27	N23-E25 PolarHBondContact O-N 3.09Å; N23-E25 VanDerWaalsContact O-N 3.07Å; E25-P27 VanDerWaalsContact O-CD 3.25Å; E25-P27 WeakPolarHBondContact O-CD 3.1Å
26	Q	29.4	Very low	39.1	Very low	176 Å²	176	119.2 Å²	119.2	82%	0.822	70%	0.702	S	S	*	*			trans	-72.5	118.4	169	-75.9	-176.2	-16.9	0	0	107.6	F28	Q26-F28 PolarHBondContact O-N 3.23Å
27	P	26.2	Very low	42	Very low	117 Å²	117	120.3 Å²	120.3	76%	0.76	71%	0.705	S	S	*	*			trans	-57.8	124.9	157.4	24.9	-29.2	0	0	0	106.1	E25 P29	E25-P27 VanDerWaalsContact O-CD 3.25Å; E25-P27 WeakPolarHBondContact O-CD 3.1Å; P27-P29 VanDerWaalsContact O-N 3.15Å
28	F	29.3	Very low	44.6	Very low	170 Å²	170	121.4 Å²	121.4	75%	0.746	70%	0.696	S	S	*	*			trans	-43.7	125	172.7	-75.7	-94.8	0	0	0	108.5	Q26 E30	Q26-F28 PolarHBondContact O-N 3.23Å; F28-E30 HydrophobicContact CB-CG 4.09Å; F28-E30 PolarHBondContact O-N 3.49Å
29	P	36.8	Very low	47.5	Very low	119 Å²	119	120.3 Å²	120.3	77%	0.773	68%	0.678	S	S	*	*			trans	-73.1	68	171.9	29.9	-31.5	0	0	0	107.9	P27	P27-P29 VanDerWaalsContact O-N 3.15Å
30	E	33.3	Very low	50.6	Low	159 Å²	159	121 Å²	121	74%	0.743	66%	0.663	S	S	*	*			trans	-82.6	114.6	173.4	-84.3	179.2	156.7	0	0	108.2	F28	F28-E30 HydrophobicContact CB-CG 4.09Å; F28-E30 PolarHBondContact O-N 3.49Å
31	E	39.9	Very low	53.8	Low	192 Å²	192	114 Å²	114	90%	0.897	63%	0.633	S	S	*	*	S	Bend	trans	89.1	-8.3	165.8	-57.9	-174	145.8	0	0	120.9	T33	E31-T33 PolarHBondContact O-N 3Å; E31-T33 VanDerWaalsContact O-N 3.09Å
32	A	43	Very low	57.1	Low	85 Å²	85	110.8 Å²	110.8	70%	0.702	60%	0.6	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	88	179.1	0	0	0	0	0	113.3
33	T	55.3	Low	60	Low	109 Å²	109	102 Å²	102	67%	0.669	56%	0.56	S	S	*	*	T	Hydrogen-bonded Turn	trans	154.2	27.3	147.5	51.5	0	0	0	0	114.1	E31	E31-T33 PolarHBondContact O-N 3Å; E31-T33 VanDerWaalsContact O-N 3.09Å
34	G	69.7	Low	63.1	Low	44 Å²	44	94.6 Å²	94.6	45%	0.454	52%	0.52	S	S	.	.	P	Polyproline II helix	trans	-64.9	152	166.4	0	0	0	0	0	112.4	S36	G34-S36 PolarHBondContact O-N 3.1Å
35	L	79.2	Confident	66.3	Low	16 Å²	16	91.8 Å²	91.8	8%	0.084	49%	0.485	C	S	.	.	P	Polyproline II helix	trans	-59.3	135.7	169.8	-70.3	152.7	0	0	0	109.5	R39 R40 L180 E186 L190	L35-R39 HydrophobicContact CB-CB 4.34Å; L35-R39 HydrophobicContact CD2-CB 4.06Å; L35-R40 HydrophobicContact CB-CG 3.88Å; L35-R40 PolarHBondContact O-NE 3.21Å; L35-L180 HydrophobicContact CD1-CB 4.03Å; L35-L180 HydrophobicContact CD2-CB 4.35Å; L35-L180 HydrophobicContact CD2-CD2 4.39Å; L35-E186 VanDerWaalsContact CB-OE1 3.28Å; L35-E186 WeakPolarHBondContact CB-OE1 3.44Å; L35-E186 HydrophobicContact CD1-CG 4.08Å; L35-E186 PolarHBondContact N-OE1 3.16Å; L35-L190 HydrophobicContact CD1-CD1 3.93Å; L35-L190 HydrophobicContact CD1-CD2 4.26Å; L35-L190 HydrophobicContact CD1-CG 4.49Å
36	S	87.5	Confident	69.6	Low	61 Å²	61	83.1 Å²	83.1	43%	0.427	44%	0.444	S	S	.	.	P	Polyproline II helix	trans	-58.9	152.6	172.8	70.4	0	0	0	0	111.3	G34 W38 R39 R40	G34-S36 PolarHBondContact O-N 3.1Å; S36-W38 PolarHBondContact O-N 2.98Å; S36-R39 PolarHBondContact O-N 2.87Å; S36-R39 WeakPolarHBondContact OG-CG 3.38Å; S36-R39 PolarHBondContact OG-N 2.71Å; S36-R40 PolarHBondContact O-N 2.96Å
37	V	88.2	Confident	72.8	Confident	110 Å²	110	74.9 Å²	74.9	67%	0.667	41%	0.406	S	S	*	.	H	α-helix	trans	-52.6	-42.9	178.7	178.2	0	0	0	0	111.2	R39 R40 V41	V37-R39 PolarHBondContact O-N 3.01Å; V37-R40 PolarHBondContact O-N 2.62Å; V37-V41 WeakPolarHBondContact O-CG2 3.36Å; V37-V41 PolarHBondContact O-N 3.33Å
38	W	90.6	Very high	76.2	Confident	144 Å²	144	69.3 Å²	69.3	55%	0.545	37%	0.37	S	S	.	.	H	α-helix	trans	-59.5	-45	175.7	174.2	-114	0	0	0	112.8	S36 R40 V41 A42 F45	S36-W38 PolarHBondContact O-N 2.98Å; W38-R40 VanDerWaalsContact C-N 3.32Å; W38-R40 PolarHBondContact O-N 3.36Å; W38-V41 PolarHBondContact O-N 3.43Å; W38-A42 WeakPolarHBondContact O-CB 3.48Å; W38-A42 PolarHBondContact O-N 3.25Å; W38-F45 HydrophobicContact CH2-CE2 4.03Å; W38-F45 HydrophobicContact CZ3-CE2 4.22Å
39	R	91.6	Very high	79.5	Confident	102 Å²	102	61.3 Å²	61.3	39%	0.385	33%	0.334	S	S	.	.	H	α-helix	trans	-63.9	-37.7	177.5	-74.1	-178.3	-178.1	-178	3.7	111.8	L35 S36 V37 A42 F43 I252	L35-R39 HydrophobicContact CB-CB 4.34Å; L35-R39 HydrophobicContact CD2-CB 4.06Å; S36-R39 PolarHBondContact O-N 2.87Å; S36-R39 WeakPolarHBondContact OG-CG 3.38Å; S36-R39 PolarHBondContact OG-N 2.71Å; V37-R39 PolarHBondContact O-N 3.01Å; R39-A42 PolarHBondContact O-N 3.4Å; R39-F43 WeakPolarHBondContact O-CB 3.04Å; R39-F43 PolarHBondContact O-N 2.97Å; R39-I252 HydrophobicContact CB-CD1 4.35Å; R39-I252 VanDerWaalsContact O-CD1 3.28Å; R39-I252 WeakPolarHBondContact O-CD1 3.43Å
40	R	91.2	Very high	82.5	Confident	72 Å²	72	55.6 Å²	55.6	27%	0.272	30%	0.298	S	S	.	.	H	α-helix	trans	-63.5	-43.9	176	-65.9	179	178.9	171.1	2.9	111.8	L35 S36 V37 W38 G44 E186 L190 I193	L35-R40 HydrophobicContact CB-CG 3.88Å; L35-R40 PolarHBondContact O-NE 3.21Å; S36-R40 PolarHBondContact O-N 2.96Å; V37-R40 PolarHBondContact O-N 2.62Å; W38-R40 VanDerWaalsContact C-N 3.32Å; W38-R40 PolarHBondContact O-N 3.36Å; R40-G44 PolarHBondContact O-N 2.88Å; R40-E186 IonicContact CZ-OE1 3.96Å; R40-E186 IonicContact NE-OE1 3.21Å; R40-E186 PolarHBondContact NE-OE1 3Å; R40-E186 VanDerWaalsContact NE-OE1 3.12Å; R40-E186 IonicContact NH2-OE1 3.66Å; R40-E186 PolarHBondContact NH2-OE1 3.33Å; R40-L190 HydrophobicContact CB-CD2 4.17Å; R40-L190 HydrophobicContact CG-CD2 4.08Å; R40-I193 HydrophobicContact CB-CD1 3.68Å
41	V	93.1	Very high	85.5	Confident	48 Å²	48	48.5 Å²	48.5	29%	0.291	27%	0.265	S	S	.	.	H	α-helix	trans	-67.9	-46.3	176.5	173.9	0	0	0	0	111.1	V37 W38 F43 G44 F45 F197	V37-V41 WeakPolarHBondContact O-CG2 3.36Å; V37-V41 PolarHBondContact O-N 3.33Å; W38-V41 PolarHBondContact O-N 3.43Å; V41-F43 VanDerWaalsContact C-N 3.27Å; V41-F43 PolarHBondContact O-N 2.81Å; V41-G44 WeakPolarHBondContact O-CA 3.38Å; V41-G44 PolarHBondContact O-N 3.26Å; V41-F45 HydrophobicContact CG1-CE1 3.88Å; V41-F45 HydrophobicContact CG1-CE2 4.2Å; V41-F45 HydrophobicContact CG1-CZ 3.58Å; V41-F45 PolarHBondContact O-N 3.23Å; V41-F197 HydrophobicContact CG1-CE2 4.39Å; V41-F197 HydrophobicContact CG1-CZ 4.16Å
42	A	94.7	Very high	88.3	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-60.2	-36.2	178.7	0	0	0	0	0	112.4	W38 R39 G44 F45 F248 I252	W38-A42 WeakPolarHBondContact O-CB 3.48Å; W38-A42 PolarHBondContact O-N 3.25Å; R39-A42 PolarHBondContact O-N 3.4Å; A42-G44 VanDerWaalsContact C-N 3.34Å; A42-F45 HydrophobicContact CB-CD2 4.45Å; A42-F45 WeakPolarHBondContact O-CB 3.37Å; A42-F45 PolarHBondContact O-N 3.44Å; A42-F248 WeakPolarHBondContact O-CD2 3.19Å; A42-I252 HydrophobicContact CB-CD1 4.27Å; A42-I252 HydrophobicContact CB-CG1 4.35Å
43	F	94.6	Very high	90.9	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-56.7	-49.6	170.8	170.4	-96.1	0	0	0	110.5	R39 V41 F45 G46 H173 I177 L180 L190 R194 I252	R39-F43 WeakPolarHBondContact O-CB 3.04Å; R39-F43 PolarHBondContact O-N 2.97Å; V41-F43 VanDerWaalsContact C-N 3.27Å; V41-F43 PolarHBondContact O-N 2.81Å; F43-F45 PolarHBondContact O-N 2.72Å; F43-F45 VanDerWaalsContact O-N 3.1Å; F43-G46 PolarHBondContact O-N 3.49Å; F43-H173 AromaticContact CD2-NE2 3.65Å; F43-H173 AromaticContact CE1-CE1 3.82Å; F43-H173 AromaticContact CE1-NE2 3.67Å; F43-H173 AromaticContact CE2-CD2 3.55Å; F43-H173 AromaticContact CE2-CE1 4Å; F43-H173 AromaticContact CE2-NE2 3.26Å; F43-H173 VanDerWaalsContact CE2-NE2 3.26Å; F43-H173 WeakPolarHBondContact CE2-NE2 3.49Å; F43-H173 AromaticContact CG-NE2 3.99Å; F43-H173 AromaticContact CZ-CD2 3.85Å; F43-H173 AromaticContact CZ-CE1 3.51Å; F43-H173 AromaticContact CZ-NE2 3.24Å; F43-H173 WeakPolarHBondContact CZ-NE2 3.32Å; F43-H173 PolarHBondContact O-NE2 2.9Å; F43-I177 HydrophobicContact CE1-CD1 4.35Å; F43-I177 HydrophobicContact CE1-CG1 4.05Å; F43-I177 HydrophobicContact CE2-CG1 3.69Å; F43-I177 HydrophobicContact CZ-CD1 3.72Å; F43-I177 HydrophobicContact CZ-CG1 3.2Å; F43-L180 HydrophobicContact CB-CD1 4.5Å; F43-L180 HydrophobicContact CD2-CD1 3.62Å; F43-L180 HydrophobicContact CE2-CD1 4.3Å; F43-L180 HydrophobicContact CG-CD1 4.33Å; F43-L190 HydrophobicContact CB-CD2 4.14Å; F43-L190 HydrophobicContact CD1-CB 3.89Å; F43-L190 HydrophobicContact CD1-CD2 3.78Å; F43-L190 HydrophobicContact CD1-CG 4.3Å; F43-L190 HydrophobicContact CE1-CB 3.79Å; F43-L190 HydrophobicContact CG-CD2 4.03Å; F43-R194 HydrophobicContact CE1-CB 4.28Å; F43-I252 HydrophobicContact CB-CD1 4.01Å
44	G	94.1	Very high	92.9	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-52.9	-33.8	178.3	0	0	0	0	0	114.8	R40 V41 A42 G46	R40-G44 PolarHBondContact O-N 2.88Å; V41-G44 WeakPolarHBondContact O-CA 3.38Å; V41-G44 PolarHBondContact O-N 3.26Å; A42-G44 VanDerWaalsContact C-N 3.34Å; G44-G46 PolarHBondContact O-N 3.02Å
45	F	97.3	Very high	94.1	Very high	21 Å²	21	28.6 Å²	28.6	9%	0.092	14%	0.14	C	C	.	.	H	α-helix	trans	-62.1	-26.3	177.5	-60.6	-27	0	0	0	113.8	W38 V41 A42 F43 H47 V48 F197 F244 L247 F248	W38-F45 HydrophobicContact CH2-CE2 4.03Å; W38-F45 HydrophobicContact CZ3-CE2 4.22Å; V41-F45 HydrophobicContact CG1-CE1 3.88Å; V41-F45 HydrophobicContact CG1-CE2 4.2Å; V41-F45 HydrophobicContact CG1-CZ 3.58Å; V41-F45 PolarHBondContact O-N 3.23Å; A42-F45 HydrophobicContact CB-CD2 4.45Å; A42-F45 WeakPolarHBondContact O-CB 3.37Å; A42-F45 PolarHBondContact O-N 3.44Å; F43-F45 PolarHBondContact O-N 2.72Å; F43-F45 VanDerWaalsContact O-N 3.1Å; F45-H47 PolarHBondContact O-N 3.5Å; F45-V48 PolarHBondContact O-N 2.82Å; F45-F197 HydrophobicContact CD1-CD1 4.25Å; F45-F197 AromaticContact CD1-CE1 3.62Å; F45-F197 HydrophobicContact CD1-CE1 3.62Å; F45-F197 HydrophobicContact CD1-CE2 4.09Å; F45-F197 AromaticContact CD1-CZ 3.54Å; F45-F197 HydrophobicContact CD1-CZ 3.54Å; F45-F197 AromaticContact CE1-CE1 3.5Å; F45-F197 HydrophobicContact CE1-CE1 3.5Å; F45-F197 VanDerWaalsContact CE1-CE1 3.5Å; F45-F197 HydrophobicContact CE1-CE2 4.16Å; F45-F197 AromaticContact CE1-CZ 3.27Å; F45-F197 HydrophobicContact CE1-CZ 3.27Å; F45-F197 HydrophobicContact CZ-CZ 4.39Å; F45-F244 HydrophobicContact CB-CD1 3.93Å; F45-F244 AromaticContact CD1-CD1 3.46Å; F45-F244 HydrophobicContact CD1-CD1 3.46Å; F45-F244 VanDerWaalsContact CD1-CD1 3.46Å; F45-F244 AromaticContact CD1-CE1 3.55Å; F45-F244 HydrophobicContact CD1-CE1 3.55Å; F45-F244 HydrophobicContact CE1-CD1 4.04Å; F45-F244 AromaticContact CE1-CE1 3.69Å; F45-F244 HydrophobicContact CE1-CE1 3.69Å; F45-F244 AromaticContact CG-CD1 3.77Å; F45-F244 HydrophobicContact CG-CD1 3.77Å; F45-F244 HydrophobicContact CG-CE1 4.28Å; F45-L247 HydrophobicContact CD2-CB 3.82Å; F45-L247 HydrophobicContact CE2-CB 4.28Å; F45-L247 HydrophobicContact CE2-CD1 4.43Å; F45-F248 HydrophobicContact CB-CB 4.11Å
46	G	96.7	Very high	95	Very high	0 Å²	0	27.9 Å²	27.9	0%	0	14%	0.136	C	C	.	.	T	Hydrogen-bonded Turn	trans	-60.8	-29.7	-174.2	0	0	0	0	0	113.9	F43 G44 H117 F248	F43-G46 PolarHBondContact O-N 3.49Å; G44-G46 PolarHBondContact O-N 3.02Å; G46-H117 PolarHBondContact O-NE2 2.06Å; G46-F248 VanDerWaalsContact CA-CG 3.43Å
47	H	96.8	Very high	95.5	Very high	3 Å²	3	25.2 Å²	25.2	1%	0.014	12%	0.117	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.3	-10.1	179.8	-142.7	45.1	0	0	0	115.4	F45 Y49 N50 D51 H173 R194	F45-H47 PolarHBondContact O-N 3.5Å; H47-Y49 PolarHBondContact O-N 3.46Å; H47-N50 PolarHBondContact O-N 3.11Å; H47-N50 VanDerWaalsContact O-N 3.15Å; H47-D51 IonicContact CD2-OD1 3.43Å; H47-D51 PolarHBondContact CD2-OD1 3.18Å; H47-D51 IonicContact CD2-OD2 2.77Å; H47-D51 PolarHBondContact CD2-OD2 3.1Å; H47-D51 IonicContact CG-OD2 3.12Å; H47-D51 IonicContact NE2-OD1 2.9Å; H47-D51 PolarHBondContact O-N 3Å; H47-H173 AromaticContact CG-ND1 3.89Å; H47-H173 AromaticContact ND1-ND1 4Å; H47-R194 HydrophobicContact CB-CG 4.31Å; H47-R194 VanDerWaalsContact CD2-CZ 3.44Å; H47-R194 PolarHBondContact CD2-NH2 3.41Å; H47-R194 PolarHBondContact NE2-NH2 2.81Å
48	V	98.2	Very high	95.8	Very high	1 Å²	1	21.9 Å²	21.9	1%	0.006	9%	0.093	C	C	.	.	H	α-helix	trans	-55.7	-40.6	-173.2	171.3	0	0	0	0	111.6	F45 D51 L52 F197 A201 F244	F45-V48 PolarHBondContact O-N 2.82Å; V48-D51 PolarHBondContact O-N 3.5Å; V48-L52 HydrophobicContact CG1-CD1 3.97Å; V48-L52 HydrophobicContact CG1-CG 4.23Å; V48-L52 VanDerWaalsContact O-CG 3.28Å; V48-L52 WeakPolarHBondContact O-CG 3.26Å; V48-L52 PolarHBondContact O-N 2.83Å; V48-F197 HydrophobicContact CG2-CB 3.78Å; V48-F197 HydrophobicContact CG2-CD1 3.71Å; V48-F197 HydrophobicContact CG2-CG 3.94Å; V48-A201 HydrophobicContact CG1-CB 4.31Å; V48-F244 HydrophobicContact CB-CB 3.99Å; V48-F244 HydrophobicContact CB-CD1 4.18Å; V48-F244 HydrophobicContact CB-CG 4.02Å; V48-F244 HydrophobicContact CG1-CB 4.06Å; V48-F244 HydrophobicContact CG1-CD1 4.12Å; V48-F244 HydrophobicContact CG1-CD2 3.8Å; V48-F244 HydrophobicContact CG1-CE2 4.27Å; V48-F244 HydrophobicContact CG1-CG 3.73Å; V48-F244 HydrophobicContact CG2-CD1 3.98Å; V48-F244 HydrophobicContact CG2-CE1 4.42Å; V48-F244 HydrophobicContact CG2-CG 4.33Å
49	Y	98.5	Very high	96.1	Very high	1 Å²	1	15.1 Å²	15.1	0%	0.004	7%	0.068	C	C	.	.	H	α-helix	trans	-63.3	-49.1	-179.6	-168.8	-172.1	0	0	0	112.2	H47 D51 L52 C53 T121 V124 F125 T238	H47-Y49 PolarHBondContact O-N 3.46Å; Y49-D51 VanDerWaalsContact C-N 3.31Å; Y49-D51 PolarHBondContact O-N 3.16Å; Y49-L52 PolarHBondContact O-N 3.05Å; Y49-C53 VanDerWaalsContact CE2-SG 3.56Å; Y49-C53 PolarHBondContact O-N 2.84Å; Y49-C53 VanDerWaalsContact O-N 3.15Å; Y49-C53 PolarHBondContact O-SG 3.34Å; Y49-T121 HydrophobicContact CD1-CG2 4.13Å; Y49-T121 HydrophobicContact CE1-CG2 4.25Å; Y49-V124 HydrophobicContact CD1-CG1 4.37Å; Y49-V124 HydrophobicContact CD2-CG1 4.4Å; Y49-V124 HydrophobicContact CE1-CB 4.13Å; Y49-V124 HydrophobicContact CE1-CG1 3.81Å; Y49-V124 HydrophobicContact CE2-CG1 3.84Å; Y49-F125 VanDerWaalsContact OH-CA 3.3Å; Y49-F125 WeakPolarHBondContact OH-CA 3.22Å; Y49-F125 PolarHBondContact OH-N 3.03Å; Y49-T238 WeakPolarHBondContact OH-CG2 3.39Å
50	N	98	Very high	96.4	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-57.4	-46.9	173.1	-88.9	27.8	0	0	0	110.5	H47 L52 C53 A54 W166 V169	H47-N50 PolarHBondContact O-N 3.11Å; H47-N50 VanDerWaalsContact O-N 3.15Å; N50-L52 VanDerWaalsContact C-N 3.33Å; N50-L52 PolarHBondContact O-N 2.79Å; N50-C53 CarbonylContact O-C 3.58Å; N50-C53 WeakPolarHBondContact O-CA 3.17Å; N50-C53 WeakPolarHBondContact O-CB 3.43Å; N50-C53 PolarHBondContact O-N 3.38Å; N50-C53 VanDerWaalsContact O-N 3.09Å; N50-A54 PolarHBondContact O-N 3.47Å; N50-W166 HydrophobicContact CB-CD2 4.44Å; N50-W166 HydrophobicContact CB-CE3 4.07Å; N50-W166 HydrophobicContact CB-CH2 4Å; N50-W166 HydrophobicContact CB-CZ2 4.43Å; N50-W166 HydrophobicContact CB-CZ3 3.88Å; N50-W166 PolarHBondContact ND2-O 2.97Å; N50-W166 WeakPolarHBondContact O-CH2 3.5Å; N50-W166 WeakPolarHBondContact O-CZ3 3.48Å; N50-V169 HydrophobicContact CB-CG1 4.4Å; N50-V169 WeakPolarHBondContact OD1-CG1 3.45Å
51	D	97.2	Very high	96.7	Very high	10 Å²	10	6.9 Å²	6.9	5%	0.053	4%	0.037	C	C	.	.	H	α-helix	trans	-64.7	-35	-175.8	-67.5	-31.6	0	0	0	113.5	H47 V48 Y49 A54 S55 T198 A201	H47-D51 IonicContact CD2-OD1 3.43Å; H47-D51 PolarHBondContact CD2-OD1 3.18Å; H47-D51 IonicContact CD2-OD2 2.77Å; H47-D51 PolarHBondContact CD2-OD2 3.1Å; H47-D51 IonicContact CG-OD2 3.12Å; H47-D51 IonicContact NE2-OD1 2.9Å; H47-D51 PolarHBondContact O-N 3Å; V48-D51 PolarHBondContact O-N 3.5Å; Y49-D51 VanDerWaalsContact C-N 3.31Å; Y49-D51 PolarHBondContact O-N 3.16Å; D51-A54 WeakPolarHBondContact O-CB 3.34Å; D51-A54 PolarHBondContact O-N 3.23Å; D51-S55 PolarHBondContact O-N 3.5Å; D51-S55 PolarHBondContact O-OG 3.44Å; D51-T198 HydrophobicContact CB-CG2 4.12Å; D51-T198 VanDerWaalsContact CG-OG1 3.29Å; D51-T198 WeakPolarHBondContact OD2-CA 3.36Å; D51-T198 VanDerWaalsContact OD2-CB 3.28Å; D51-T198 WeakPolarHBondContact OD2-CB 3.32Å; D51-T198 PolarHBondContact OD2-OG1 2.92Å; D51-A201 HydrophobicContact CB-CB 3.6Å
52	L	98.3	Very high	96.9	Very high	0 Å²	0	4.8 Å²	4.8	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-60.9	-48.6	171.6	-71.5	165	0	0	0	110.3	V48 Y49 N50 S55 M56 A201 V204 T205 V237 V240	V48-L52 HydrophobicContact CG1-CD1 3.97Å; V48-L52 HydrophobicContact CG1-CG 4.23Å; V48-L52 VanDerWaalsContact O-CG 3.28Å; V48-L52 WeakPolarHBondContact O-CG 3.26Å; V48-L52 PolarHBondContact O-N 2.83Å; Y49-L52 PolarHBondContact O-N 3.05Å; N50-L52 VanDerWaalsContact C-N 3.33Å; N50-L52 PolarHBondContact O-N 2.79Å; L52-S55 PolarHBondContact O-N 2.93Å; L52-M56 PolarHBondContact O-N 2.82Å; L52-A201 HydrophobicContact CD2-CB 3.94Å; L52-A201 VanDerWaalsContact CD2-O 3.32Å; L52-A201 WeakPolarHBondContact CD2-O 3.33Å; L52-A201 HydrophobicContact CG-CB 3.82Å; L52-V204 HydrophobicContact CD2-CB 3.96Å; L52-V204 HydrophobicContact CD2-CG1 3.86Å; L52-T205 WeakPolarHBondContact CD2-OG1 3.41Å; L52-T205 PolarHBondContact O-OG1 3.27Å; L52-T205 VanDerWaalsContact O-OG1 3.08Å; L52-V237 HydrophobicContact CB-CG1 3.58Å; L52-V237 HydrophobicContact CB-CG2 4.42Å; L52-V237 HydrophobicContact CD1-CG1 4.45Å; L52-V240 HydrophobicContact CD1-CB 4.46Å; L52-V240 HydrophobicContact CD1-CG1 4.13Å
53	C	98.4	Very high	97	Very high	0 Å²	0	4.8 Å²	4.8	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-63.9	-38.8	178.1	-64.1	0	0	0	0	112.3	Y49 N50 S55 M56 W57 F128 F162 W166	Y49-C53 VanDerWaalsContact CE2-SG 3.56Å; Y49-C53 PolarHBondContact O-N 2.84Å; Y49-C53 VanDerWaalsContact O-N 3.15Å; Y49-C53 PolarHBondContact O-SG 3.34Å; N50-C53 CarbonylContact O-C 3.58Å; N50-C53 WeakPolarHBondContact O-CA 3.17Å; N50-C53 WeakPolarHBondContact O-CB 3.43Å; N50-C53 PolarHBondContact O-N 3.38Å; N50-C53 VanDerWaalsContact O-N 3.09Å; C53-S55 VanDerWaalsContact C-N 3.3Å; C53-S55 PolarHBondContact O-N 3.19Å; C53-M56 PolarHBondContact O-N 3.45Å; C53-W57 WeakPolarHBondContact O-CB 3.44Å; C53-W57 PolarHBondContact O-N 3.16Å; C53-F128 HydrophobicContact CB-CD1 4.48Å; C53-F128 HydrophobicContact CB-CD2 3.78Å; C53-F128 HydrophobicContact CB-CE1 4.23Å; C53-F128 HydrophobicContact CB-CE2 3.47Å; C53-F128 VanDerWaalsContact CB-CE2 3.47Å; C53-F128 HydrophobicContact CB-CG 4.27Å; C53-F128 HydrophobicContact CB-CZ 3.73Å; C53-F128 WeakPolarHBondContact SG-CD1 3.49Å; C53-F128 VanDerWaalsContact SG-CE1 3.59Å; C53-F128 VanDerWaalsContact SG-CG 3.55Å; C53-F162 HydrophobicContact CB-CE2 3.82Å; C53-F162 HydrophobicContact CB-CZ 3.86Å; C53-W166 HydrophobicContact CB-CZ3 4.44Å
54	A	96.5	Very high	97.1	Very high	12 Å²	12	4.8 Å²	4.8	10%	0.099	2%	0.024	C	C	.	.	H	α-helix	trans	-58.8	-45.2	178.6	0	0	0	0	0	111.2	N50 D51 M56 W57 F58 W166	N50-A54 PolarHBondContact O-N 3.47Å; D51-A54 WeakPolarHBondContact O-CB 3.34Å; D51-A54 PolarHBondContact O-N 3.23Å; A54-M56 VanDerWaalsContact C-N 3.26Å; A54-M56 PolarHBondContact O-N 3.1Å; A54-W57 PolarHBondContact O-N 3.35Å; A54-F58 WeakPolarHBondContact O-CD2 3.11Å; A54-F58 PolarHBondContact O-N 3.13Å; A54-W166 HydrophobicContact CB-CH2 3.24Å; A54-W166 HydrophobicContact CB-CZ2 4.41Å; A54-W166 HydrophobicContact CB-CZ3 3.56Å
55	S	96.1	Very high	97.2	Very high	0 Å²	0	4.8 Å²	4.8	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-62.4	-39.1	-177.1	-56.7	0	0	0	0	110.4	D51 L52 C53 S59 S202	D51-S55 PolarHBondContact O-N 3.5Å; D51-S55 PolarHBondContact O-OG 3.44Å; L52-S55 PolarHBondContact O-N 2.93Å; C53-S55 VanDerWaalsContact C-N 3.3Å; C53-S55 PolarHBondContact O-N 3.19Å; S55-S59 WeakPolarHBondContact O-CB 3.38Å; S55-S59 PolarHBondContact O-N 2.87Å; S55-S59 PolarHBondContact O-OG 2.96Å; S55-S202 VanDerWaalsContact OG-CA 3.3Å; S55-S202 WeakPolarHBondContact OG-CA 3.43Å; S55-S202 WeakPolarHBondContact OG-CB 3.16Å; S55-S202 PolarHBondContact OG-OG 2.93Å
56	M	97.3	Very high	97.1	Very high	0 Å²	0	4.9 Å²	4.9	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-72.4	-44.7	172.1	-65.3	-167.8	73.2	0	0	113.1	L52 C53 A54 Y60 L61 F128 F132 T205 V233 V237	L52-M56 PolarHBondContact O-N 2.82Å; C53-M56 PolarHBondContact O-N 3.45Å; A54-M56 VanDerWaalsContact C-N 3.26Å; A54-M56 PolarHBondContact O-N 3.1Å; M56-Y60 CarbonylContact O-C 3.54Å; M56-Y60 WeakPolarHBondContact O-CA 3.28Å; M56-Y60 WeakPolarHBondContact O-CB 3.32Å; M56-Y60 PolarHBondContact O-N 2.67Å; M56-L61 PolarHBondContact O-N 3.34Å; M56-F128 HydrophobicContact CB-CZ 3.87Å; M56-F128 HydrophobicContact CG-CZ 4.21Å; M56-F128 HydrophobicContact SD-CE1 3.83Å; M56-F128 HydrophobicContact SD-CZ 3.7Å; M56-F132 HydrophobicContact CB-CE2 3.91Å; M56-F132 HydrophobicContact CB-CZ 3.8Å; M56-F132 HydrophobicContact CE-CB 4.47Å; M56-F132 HydrophobicContact CE-CD1 3.91Å; M56-F132 HydrophobicContact CE-CD2 3.77Å; M56-F132 HydrophobicContact CE-CE1 4.04Å; M56-F132 HydrophobicContact CE-CE2 3.91Å; M56-F132 HydrophobicContact CE-CG 3.77Å; M56-F132 HydrophobicContact CE-CZ 4.05Å; M56-F132 HydrophobicContact SD-CE2 4.42Å; M56-T205 HydrophobicContact CB-CG2 4.42Å; M56-T205 HydrophobicContact CG-CG2 3.36Å; M56-V233 HydrophobicContact CE-CB 4.16Å; M56-V233 HydrophobicContact CE-CG1 3.76Å; M56-V233 HydrophobicContact SD-CG1 3.81Å; M56-V237 HydrophobicContact SD-CB 4.28Å; M56-V237 HydrophobicContact SD-CG1 4.44Å; M56-V237 HydrophobicContact SD-CG2 3.96Å
57	W	97.5	Very high	96.9	Very high	6 Å²	6	5.8 Å²	5.8	2%	0.023	3%	0.028	C	C	.	.	H	α-helix	trans	-59	-53.8	-177.9	174.6	-90.2	0	0	0	111.2	C53 A54 L61 F80 L131 V159 F162	C53-W57 WeakPolarHBondContact O-CB 3.44Å; C53-W57 PolarHBondContact O-N 3.16Å; A54-W57 PolarHBondContact O-N 3.35Å; W57-L61 HydrophobicContact CD2-CD2 3.93Å; W57-L61 HydrophobicContact CE3-CD1 4.01Å; W57-L61 HydrophobicContact CE3-CD2 3.75Å; W57-L61 HydrophobicContact CE3-CG 4.39Å; W57-L61 HydrophobicContact CH2-CD2 3.5Å; W57-L61 VanDerWaalsContact CH2-CD2 3.5Å; W57-L61 HydrophobicContact CZ2-CD2 3.68Å; W57-L61 HydrophobicContact CZ3-CD1 3.94Å; W57-L61 HydrophobicContact CZ3-CD2 3.53Å; W57-L61 HydrophobicContact CZ3-CG 4.37Å; W57-L61 WeakPolarHBondContact O-CB 3.31Å; W57-F80 HydrophobicContact CZ2-CD2 4.4Å; W57-F80 AromaticContact NE1-CE2 3.72Å; W57-L131 HydrophobicContact CE3-CD1 4.38Å; W57-L131 HydrophobicContact CZ3-CD1 4.14Å; W57-V159 HydrophobicContact CH2-CG1 3.77Å; W57-V159 HydrophobicContact CH2-CG2 4.48Å; W57-V159 HydrophobicContact CZ3-CG1 4.25Å; W57-V159 HydrophobicContact CZ3-CG2 4.4Å; W57-F162 HydrophobicContact CD2-CE1 4.11Å; W57-F162 HydrophobicContact CE3-CD1 4.07Å; W57-F162 AromaticContact CE3-CE1 3.7Å; W57-F162 HydrophobicContact CE3-CE1 3.7Å; W57-F162 HydrophobicContact CZ3-CD1 4.19Å; W57-F162 HydrophobicContact CZ3-CE1 4.27Å
58	F	95.7	Very high	96.8	Very high	40 Å²	40	5.8 Å²	5.8	18%	0.175	3%	0.028	C	C	.	.	H	α-helix	trans	-71.3	-43.5	-178.2	-74.2	-74.3	0	0	0	111.2	A54 F80 N312 T316	A54-F58 WeakPolarHBondContact O-CD2 3.11Å; A54-F58 PolarHBondContact O-N 3.13Å; F58-F80 HydrophobicContact CD1-CE2 4.38Å; F58-F80 HydrophobicContact CD1-CZ 4.05Å; F58-F80 AromaticContact CE1-CZ 3.97Å; F58-F80 HydrophobicContact CE1-CZ 3.97Å; F58-N312 HydrophobicContact CE1-CB 4.41Å; F58-T316 WeakPolarHBondContact O-CA 3.08Å; F58-T316 PolarHBondContact O-OG1 2.71Å; F58-T316 VanDerWaalsContact O-OG1 3.06Å
59	S	96.6	Very high	96.6	Very high	1 Å²	1	6 Å²	6	1%	0.007	3%	0.029	C	C	.	.	H	α-helix	trans	-84.3	-34.7	-172.3	-42.1	0	0	0	0	114	S55 P319	S55-S59 WeakPolarHBondContact O-CB 3.38Å; S55-S59 PolarHBondContact O-N 2.87Å; S55-S59 PolarHBondContact O-OG 2.96Å; S59-P319 VanDerWaalsContact O-CG 3.31Å; S59-P319 WeakPolarHBondContact O-CG 3.49Å
60	Y	97.3	Very high	96.3	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-122.5	-10.8	-163.4	-57.7	-50.8	0	0	0	115.4	M56 L62 V63 F64 F206 V209 F230 P319 I333 A334	M56-Y60 CarbonylContact O-C 3.54Å; M56-Y60 WeakPolarHBondContact O-CA 3.28Å; M56-Y60 WeakPolarHBondContact O-CB 3.32Å; M56-Y60 PolarHBondContact O-N 2.67Å; Y60-L62 PolarHBondContact O-N 3.49Å; Y60-V63 PolarHBondContact O-N 2.74Å; Y60-F64 WeakPolarHBondContact O-CB 3.28Å; Y60-F64 PolarHBondContact O-N 3.42Å; Y60-F206 AromaticContact CE2-CD1 3.75Å; Y60-F206 HydrophobicContact CE2-CD1 3.75Å; Y60-F206 AromaticContact CE2-CE1 3.76Å; Y60-F206 HydrophobicContact CE2-CE1 3.76Å; Y60-F206 AromaticContact CZ-CD1 3.79Å; Y60-F206 AromaticContact CZ-CE1 3.86Å; Y60-F206 WeakPolarHBondContact OH-CD1 3.41Å; Y60-F206 WeakPolarHBondContact OH-CE1 3.23Å; Y60-V209 HydrophobicContact CD2-CG2 3.83Å; Y60-V209 HydrophobicContact CE1-CG1 4.19Å; Y60-V209 HydrophobicContact CE2-CB 4.05Å; Y60-V209 HydrophobicContact CE2-CG1 4.1Å; Y60-V209 HydrophobicContact CE2-CG2 3.53Å; Y60-F230 HydrophobicContact CD1-CE1 4.32Å; Y60-F230 HydrophobicContact CG-CE1 4.04Å; Y60-P319 HydrophobicContact CE1-CG 4.31Å; Y60-I333 HydrophobicContact CE1-CB 4.36Å; Y60-I333 HydrophobicContact CE1-CD1 4.43Å; Y60-I333 HydrophobicContact CE1-CG1 3.91Å; Y60-I333 WeakPolarHBondContact CE1-O 3.43Å; Y60-I333 PolarHBondContact OH-O 2.99Å; Y60-A334 WeakPolarHBondContact OH-CA 3.37Å
61	L	98	Very high	96.1	Very high	1 Å²	1	11.8 Å²	11.8	1%	0.005	6%	0.06	C	C	.	.	H	α-helix	trans	-57.4	-53.6	178.6	-172.6	76	0	0	0	111.2	M56 W57 V63 F64 F65 I79 F80 F132	M56-L61 PolarHBondContact O-N 3.34Å; W57-L61 HydrophobicContact CD2-CD2 3.93Å; W57-L61 HydrophobicContact CE3-CD1 4.01Å; W57-L61 HydrophobicContact CE3-CD2 3.75Å; W57-L61 HydrophobicContact CE3-CG 4.39Å; W57-L61 HydrophobicContact CH2-CD2 3.5Å; W57-L61 VanDerWaalsContact CH2-CD2 3.5Å; W57-L61 HydrophobicContact CZ2-CD2 3.68Å; W57-L61 HydrophobicContact CZ3-CD1 3.94Å; W57-L61 HydrophobicContact CZ3-CD2 3.53Å; W57-L61 HydrophobicContact CZ3-CG 4.37Å; W57-L61 WeakPolarHBondContact O-CB 3.31Å; L61-V63 VanDerWaalsContact C-N 3.32Å; L61-V63 PolarHBondContact O-N 2.9Å; L61-F64 PolarHBondContact O-N 3.37Å; L61-F65 HydrophobicContact CD1-CD2 3.96Å; L61-F65 HydrophobicContact CD1-CE2 3.66Å; L61-F65 HydrophobicContact CG-CD2 4.17Å; L61-F65 HydrophobicContact CG-CE2 4.33Å; L61-F65 VanDerWaalsContact O-CD2 3.3Å; L61-F65 WeakPolarHBondContact O-CD2 3.36Å; L61-F65 PolarHBondContact O-N 3.26Å; L61-I79 HydrophobicContact CD1-CG2 4.4Å; L61-I79 HydrophobicContact CD2-CG2 4.07Å; L61-I79 HydrophobicContact CG-CG2 4.43Å; L61-F80 HydrophobicContact CD2-CB 4.39Å; L61-F80 HydrophobicContact CD2-CD2 3.86Å; L61-F132 HydrophobicContact CD1-CZ 4.36Å
62	L	97.3	Very high	95.9	Very high	4 Å²	4	13.2 Å²	13.2	2%	0.021	7%	0.07	C	C	.	.	H	α-helix	trans	-65.5	-36.2	179.4	-65.8	175	0	0	0	112.5	Y60 K66 A76 F80 T316 Y317 L320 V441 Q445	Y60-L62 PolarHBondContact O-N 3.49Å; L62-K66 VanDerWaalsContact O-CB 3.22Å; L62-K66 WeakPolarHBondContact O-CB 3.19Å; L62-K66 VanDerWaalsContact O-CG 3.27Å; L62-K66 WeakPolarHBondContact O-CG 3.2Å; L62-K66 PolarHBondContact O-N 3.38Å; L62-A76 HydrophobicContact CD2-CB 4.09Å; L62-F80 HydrophobicContact CD2-CB 4.44Å; L62-T316 HydrophobicContact CD1-CG2 3.27Å; L62-T316 HydrophobicContact CG-CG2 4.22Å; L62-Y317 HydrophobicContact CD1-CE1 3.97Å; L62-L320 HydrophobicContact CB-CD1 4.08Å; L62-L320 HydrophobicContact CD1-CD1 4.46Å; L62-V441 HydrophobicContact CD1-CG1 4.32Å; L62-Q445 VanDerWaalsContact CD1-NE2 3.31Å; L62-Q445 HydrophobicContact CD2-CG 4.43Å
63	V	96.4	Very high	95.6	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-61	-50.2	175.7	176.8	0	0	0	0	109.8	Y60 L61 K66 K67 V222 F230 P319 L320 L323	Y60-V63 PolarHBondContact O-N 2.74Å; L61-V63 VanDerWaalsContact C-N 3.32Å; L61-V63 PolarHBondContact O-N 2.9Å; V63-K66 PolarHBondContact O-N 2.85Å; V63-K67 HydrophobicContact CG1-CB 4.45Å; V63-K67 HydrophobicContact CG1-CG 4.36Å; V63-K67 WeakPolarHBondContact O-CA 3.45Å; V63-K67 WeakPolarHBondContact O-CB 3.28Å; V63-K67 PolarHBondContact O-N 3.39Å; V63-V222 HydrophobicContact CG1-CB 4.35Å; V63-V222 HydrophobicContact CG1-CG1 4.12Å; V63-V222 HydrophobicContact CG1-CG2 4.14Å; V63-F230 HydrophobicContact CG1-CZ 4.24Å; V63-P319 HydrophobicContact CG2-CB 3.65Å; V63-L320 HydrophobicContact CG2-CD2 4.18Å; V63-L320 HydrophobicContact CG2-CG 4.22Å; V63-L323 HydrophobicContact CG1-CD1 4.35Å
64	F	97.2	Very high	95.5	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	9%	0.089	C	C	.	.	I	π-helix	trans	-59.9	-53	179.1	-178.2	-103.9	0	0	0	111.5	Y60 L61 K66 V68 L69 L131 F132 F230	Y60-F64 WeakPolarHBondContact O-CB 3.28Å; Y60-F64 PolarHBondContact O-N 3.42Å; L61-F64 PolarHBondContact O-N 3.37Å; F64-K66 VanDerWaalsContact C-N 3.33Å; F64-K66 PolarHBondContact O-N 2.91Å; F64-V68 HydrophobicContact CD2-CB 3.81Å; F64-V68 HydrophobicContact CD2-CG1 4Å; F64-V68 HydrophobicContact CD2-CG2 3.87Å; F64-V68 HydrophobicContact CE2-CB 4.07Å; F64-V68 HydrophobicContact CE2-CG1 3.76Å; F64-V68 HydrophobicContact CE2-CG2 4.44Å; F64-V68 HydrophobicContact CG-CB 4.41Å; F64-V68 HydrophobicContact CZ-CG1 4.49Å; F64-V68 WeakPolarHBondContact O-CA 3.47Å; F64-V68 WeakPolarHBondContact O-CB 3.42Å; F64-V68 PolarHBondContact O-N 2.61Å; F64-L69 HydrophobicContact CD1-CD1 4.07Å; F64-L69 HydrophobicContact CD1-CG 4.18Å; F64-L69 HydrophobicContact CE1-CD1 3.59Å; F64-L69 HydrophobicContact CE1-CD2 4.16Å; F64-L69 HydrophobicContact CE1-CG 3.76Å; F64-L69 HydrophobicContact CZ-CD1 4.35Å; F64-L69 HydrophobicContact CZ-CD2 4.1Å; F64-L69 HydrophobicContact CZ-CG 4.14Å; F64-L69 PolarHBondContact O-N 3.49Å; F64-L131 WeakPolarHBondContact CE1-O 3.47Å; F64-F132 HydrophobicContact CB-CD1 4.01Å; F64-F132 HydrophobicContact CB-CE1 4.08Å; F64-F132 HydrophobicContact CD1-CD1 4.22Å; F64-F132 HydrophobicContact CD2-CD1 4.23Å; F64-F132 WeakPolarHBondContact CE2-O 3.3Å; F64-F132 AromaticContact CG-CD1 3.91Å; F64-F132 HydrophobicContact CG-CD1 3.91Å; F64-F132 HydrophobicContact CG-CE1 4.45Å; F64-F132 WeakPolarHBondContact CZ-O 3.29Å; F64-F230 HydrophobicContact CD2-CB 3.63Å; F64-F230 HydrophobicContact CD2-CD1 4.46Å; F64-F230 AromaticContact CD2-CD2 3.86Å; F64-F230 HydrophobicContact CD2-CD2 3.86Å; F64-F230 AromaticContact CD2-CG 3.73Å; F64-F230 HydrophobicContact CD2-CG 3.73Å; F64-F230 HydrophobicContact CE2-CB 3.79Å; F64-F230 HydrophobicContact CE2-CG 4.35Å
65	F	96.5	Very high	95.5	Very high	1 Å²	1	15.6 Å²	15.6	0%	0.004	9%	0.086	C	C	.	.	I	π-helix	trans	-63.1	-38.3	-177.6	-84.9	-97	0	0	0	112.6	L61 L69 L70 F71 A76 I79 Y155	L61-F65 HydrophobicContact CD1-CD2 3.96Å; L61-F65 HydrophobicContact CD1-CE2 3.66Å; L61-F65 HydrophobicContact CG-CD2 4.17Å; L61-F65 HydrophobicContact CG-CE2 4.33Å; L61-F65 VanDerWaalsContact O-CD2 3.3Å; L61-F65 WeakPolarHBondContact O-CD2 3.36Å; L61-F65 PolarHBondContact O-N 3.26Å; F65-L69 HydrophobicContact CD1-CD1 3.95Å; F65-L69 HydrophobicContact CE1-CD1 3.96Å; F65-L69 HydrophobicContact CG-CD1 4.35Å; F65-L69 HydrophobicContact CZ-CD1 4.36Å; F65-L69 CarbonylContact O-C 3.58Å; F65-L69 WeakPolarHBondContact O-CB 3.49Å; F65-L70 PolarHBondContact O-N 2.66Å; F65-L70 VanDerWaalsContact O-N 3.16Å; F65-F71 AromaticContact CD1-CD2 3.64Å; F65-F71 HydrophobicContact CD1-CD2 3.64Å; F65-F71 HydrophobicContact CD1-CE1 4.41Å; F65-F71 AromaticContact CD1-CE2 3.52Å; F65-F71 HydrophobicContact CD1-CE2 3.52Å; F65-F71 HydrophobicContact CD1-CG 4.14Å; F65-F71 AromaticContact CD1-CZ 3.91Å; F65-F71 HydrophobicContact CD1-CZ 3.91Å; F65-F71 HydrophobicContact CE1-CD2 4.37Å; F65-F71 AromaticContact CE1-CE2 3.79Å; F65-F71 HydrophobicContact CE1-CE2 3.79Å; F65-F71 HydrophobicContact CE1-CZ 4.01Å; F65-F71 WeakPolarHBondContact O-CB 3.42Å; F65-F71 PolarHBondContact O-N 2.65Å; F65-A76 HydrophobicContact CB-CB 4.1Å; F65-I79 HydrophobicContact CD1-CG1 4.05Å; F65-I79 HydrophobicContact CE1-CB 4.47Å; F65-I79 HydrophobicContact CE1-CD1 4.16Å; F65-I79 HydrophobicContact CE1-CG1 3.71Å; F65-I79 HydrophobicContact CE1-CG2 4.26Å; F65-I79 HydrophobicContact CE2-CG2 4.1Å; F65-I79 HydrophobicContact CZ-CD1 4.49Å; F65-I79 HydrophobicContact CZ-CG1 4.21Å; F65-I79 HydrophobicContact CZ-CG2 3.95Å; F65-Y155 AromaticContact CE1-CD2 3.52Å; F65-Y155 HydrophobicContact CE1-CD2 3.52Å; F65-Y155 AromaticContact CE1-CE2 3.82Å; F65-Y155 HydrophobicContact CE1-CE2 3.82Å; F65-Y155 AromaticContact CE1-CG 3.94Å; F65-Y155 HydrophobicContact CE1-CG 3.94Å; F65-Y155 HydrophobicContact CZ-CD1 4.04Å; F65-Y155 AromaticContact CZ-CD2 3.83Å; F65-Y155 HydrophobicContact CZ-CD2 3.83Å; F65-Y155 HydrophobicContact CZ-CE1 4.37Å; F65-Y155 HydrophobicContact CZ-CE2 4.17Å; F65-Y155 AromaticContact CZ-CG 3.77Å; F65-Y155 HydrophobicContact CZ-CG 3.77Å
66	K	94	Very high	95.5	Very high	23 Å²	23	15.6 Å²	15.6	10%	0.1	9%	0.087	C	C	.	.	I	π-helix	trans	-86	-43.8	-177.5	-66.4	-178.2	59.6	-179.9	0	114.6	L62 V63 F64 L70 A76 L320 E448	L62-K66 VanDerWaalsContact O-CB 3.22Å; L62-K66 WeakPolarHBondContact O-CB 3.19Å; L62-K66 VanDerWaalsContact O-CG 3.27Å; L62-K66 WeakPolarHBondContact O-CG 3.2Å; L62-K66 PolarHBondContact O-N 3.38Å; V63-K66 PolarHBondContact O-N 2.85Å; F64-K66 VanDerWaalsContact C-N 3.33Å; F64-K66 PolarHBondContact O-N 2.91Å; K66-L70 VanDerWaalsContact O-CA 3.29Å; K66-L70 WeakPolarHBondContact O-CA 3.33Å; K66-L70 PolarHBondContact O-N 3.3Å; K66-A76 HydrophobicContact CD-CB 4.22Å; K66-A76 HydrophobicContact CG-CB 3.65Å; K66-L320 HydrophobicContact CD-CD1 4.32Å; K66-E448 WeakPolarHBondContact CE-OE2 3.41Å; K66-E448 IonicContact NZ-OE1 2.62Å; K66-E448 PolarHBondContact NZ-OE1 3.24Å; K66-E448 IonicContact NZ-OE2 3.07Å; K66-E448 PolarHBondContact NZ-OE2 2.94Å
67	K	93.1	Very high	95.5	Very high	19 Å²	19	15.6 Å²	15.6	8%	0.083	9%	0.087	C	C	.	.	I	π-helix	trans	-89.9	-33.9	-174.1	-66.4	-72.7	-169	166.3	0	112.6	V63 D221 V222 T223 P224 E324	V63-K67 HydrophobicContact CG1-CB 4.45Å; V63-K67 HydrophobicContact CG1-CG 4.36Å; V63-K67 WeakPolarHBondContact O-CA 3.45Å; V63-K67 WeakPolarHBondContact O-CB 3.28Å; V63-K67 PolarHBondContact O-N 3.39Å; K67-D221 IonicContact NZ-OD1 3.61Å; K67-D221 PolarHBondContact NZ-OD1 3.32Å; K67-D221 IonicContact NZ-OD2 2.96Å; K67-D221 PolarHBondContact NZ-OD2 2.84Å; K67-V222 HydrophobicContact CB-CB 3.87Å; K67-V222 HydrophobicContact CB-CG1 3.69Å; K67-V222 HydrophobicContact CG-CB 4.25Å; K67-T223 CarbonylContact O-C 3.56Å; K67-P224 WeakPolarHBondContact O-CD 3.36Å; K67-E324 WeakPolarHBondContact CE-OE1 3.34Å; K67-E324 VanDerWaalsContact NZ-CD 3.3Å; K67-E324 IonicContact NZ-OE1 3.14Å; K67-E324 PolarHBondContact NZ-OE1 3.32Å; K67-E324 IonicContact NZ-OE2 2.68Å
68	V	94.3	Very high	95.5	Very high	2 Å²	2	19.2 Å²	19.2	1%	0.012	10%	0.104	C	C	.	.	I	π-helix	trans	-95.3	-50.5	-176.8	-175	0	0	0	0	111.2	F64 V222 P224 D226 A227 F230	F64-V68 HydrophobicContact CD2-CB 3.81Å; F64-V68 HydrophobicContact CD2-CG1 4Å; F64-V68 HydrophobicContact CD2-CG2 3.87Å; F64-V68 HydrophobicContact CE2-CB 4.07Å; F64-V68 HydrophobicContact CE2-CG1 3.76Å; F64-V68 HydrophobicContact CE2-CG2 4.44Å; F64-V68 HydrophobicContact CG-CB 4.41Å; F64-V68 HydrophobicContact CZ-CG1 4.49Å; F64-V68 WeakPolarHBondContact O-CA 3.47Å; F64-V68 WeakPolarHBondContact O-CB 3.42Å; F64-V68 PolarHBondContact O-N 2.61Å; V68-V222 HydrophobicContact CG2-CG1 3.73Å; V68-P224 WeakPolarHBondContact O-CB 3.28Å; V68-D226 HydrophobicContact CG2-CB 4.35Å; V68-A227 HydrophobicContact CG1-CB 3.44Å; V68-A227 VanDerWaalsContact CG1-CB 3.44Å; V68-F230 HydrophobicContact CG2-CD2 3.85Å; V68-F230 HydrophobicContact CG2-CE2 3.87Å
69	L	94.2	Very high	95.6	Very high	6 Å²	6	17.3 Å²	17.3	3%	0.031	10%	0.095	C	C	.	.	S	Bend	trans	-88.1	-7.5	179.4	-57.7	-175.6	0	0	0	113.9	F64 F65 F71 R134 Y140 Y155	F64-L69 HydrophobicContact CD1-CD1 4.07Å; F64-L69 HydrophobicContact CD1-CG 4.18Å; F64-L69 HydrophobicContact CE1-CD1 3.59Å; F64-L69 HydrophobicContact CE1-CD2 4.16Å; F64-L69 HydrophobicContact CE1-CG 3.76Å; F64-L69 HydrophobicContact CZ-CD1 4.35Å; F64-L69 HydrophobicContact CZ-CD2 4.1Å; F64-L69 HydrophobicContact CZ-CG 4.14Å; F64-L69 PolarHBondContact O-N 3.49Å; F65-L69 HydrophobicContact CD1-CD1 3.95Å; F65-L69 HydrophobicContact CE1-CD1 3.96Å; F65-L69 HydrophobicContact CG-CD1 4.35Å; F65-L69 HydrophobicContact CZ-CD1 4.36Å; F65-L69 CarbonylContact O-C 3.58Å; F65-L69 WeakPolarHBondContact O-CB 3.49Å; L69-F71 VanDerWaalsContact C-N 3.3Å; L69-F71 HydrophobicContact CB-CD1 3.81Å; L69-F71 HydrophobicContact CB-CE1 3.88Å; L69-F71 HydrophobicContact CD1-CE1 4.23Å; L69-F71 PolarHBondContact O-N 2.89Å; L69-R134 HydrophobicContact CD2-CG 3.89Å; L69-Y140 HydrophobicContact CD2-CE1 4.21Å; L69-Y155 HydrophobicContact CD1-CE2 3.75Å; L69-Y155 VanDerWaalsContact CD1-OH 3.28Å; L69-Y155 WeakPolarHBondContact CD1-OH 3.42Å
70	L	92.3	Very high	95.7	Very high	114 Å²	114	17.2 Å²	17.2	60%	0.597	10%	0.095	S	C	*	.			trans	59.8	34.2	177.5	-54	177.4	0	0	0	114.2	F65 K66 P224	F65-L70 PolarHBondContact O-N 2.66Å; F65-L70 VanDerWaalsContact O-N 3.16Å; K66-L70 VanDerWaalsContact O-CA 3.29Å; K66-L70 WeakPolarHBondContact O-CA 3.33Å; K66-L70 PolarHBondContact O-N 3.3Å; L70-P224 HydrophobicContact CD1-CG 3.92Å; L70-P224 HydrophobicContact CD2-CG 4.05Å; L70-P224 HydrophobicContact CG-CG 3.99Å
71	F	93.6	Very high	95.7	Very high	9 Å²	9	18.8 Å²	18.8	4%	0.039	10%	0.103	C	C	.	.			trans	-69.4	144.5	173.9	-81.2	32.2	0	0	0	111	F65 L69 A75 A76 Q151 L152 Y155	F65-F71 AromaticContact CD1-CD2 3.64Å; F65-F71 HydrophobicContact CD1-CD2 3.64Å; F65-F71 HydrophobicContact CD1-CE1 4.41Å; F65-F71 AromaticContact CD1-CE2 3.52Å; F65-F71 HydrophobicContact CD1-CE2 3.52Å; F65-F71 HydrophobicContact CD1-CG 4.14Å; F65-F71 AromaticContact CD1-CZ 3.91Å; F65-F71 HydrophobicContact CD1-CZ 3.91Å; F65-F71 HydrophobicContact CE1-CD2 4.37Å; F65-F71 AromaticContact CE1-CE2 3.79Å; F65-F71 HydrophobicContact CE1-CE2 3.79Å; F65-F71 HydrophobicContact CE1-CZ 4.01Å; F65-F71 WeakPolarHBondContact O-CB 3.42Å; F65-F71 PolarHBondContact O-N 2.65Å; L69-F71 VanDerWaalsContact C-N 3.3Å; L69-F71 HydrophobicContact CB-CD1 3.81Å; L69-F71 HydrophobicContact CB-CE1 3.88Å; L69-F71 HydrophobicContact CD1-CE1 4.23Å; L69-F71 PolarHBondContact O-N 2.89Å; F71-A75 HydrophobicContact CB-CB 4.29Å; F71-A75 HydrophobicContact CD2-CB 3.76Å; F71-A75 HydrophobicContact CG-CB 4.35Å; F71-A76 HydrophobicContact CB-CB 4.39Å; F71-Q151 HydrophobicContact CE1-CB 3.96Å; F71-Q151 HydrophobicContact CE1-CG 4.4Å; F71-Q151 HydrophobicContact CZ-CB 3.48Å; F71-Q151 VanDerWaalsContact CZ-CB 3.48Å; F71-Q151 HydrophobicContact CZ-CG 4.39Å; F71-L152 HydrophobicContact CD2-CD2 4.26Å; F71-L152 HydrophobicContact CE2-CD2 3.7Å; F71-L152 HydrophobicContact CE2-CG 4.1Å; F71-Y155 HydrophobicContact CZ-CD2 4.28Å; F71-Y155 HydrophobicContact CZ-CE2 4.13Å
72	S	93.3	Very high	95.7	Very high	40 Å²	40	21.1 Å²	21.1	28%	0.28	12%	0.115	S	C	.	.			trans	-54.9	152	162.4	69.4	0	0	0	0	111.5	A75 A76 E148	S72-A75 PolarHBondContact O-N 3.28Å; S72-A75 WeakPolarHBondContact OG-CB 3.47Å; S72-A75 PolarHBondContact OG-N 3.38Å; S72-A76 PolarHBondContact O-N 3.46Å; S72-E148 WeakPolarHBondContact CB-OE2 3.27Å; S72-E148 PolarHBondContact N-OE1 3.34Å; S72-E148 PolarHBondContact OG-OE2 3.06Å
73	G	93.1	Very high	95.7	Very high	8 Å²	8	21 Å²	21	8%	0.082	11%	0.114	C	C	.	.	H	α-helix	trans	-46.5	-60.6	173.5	0	0	0	0	0	111.7	A75 A76 G77 Q445	G73-A75 VanDerWaalsContact C-N 3.28Å; G73-A75 PolarHBondContact O-N 3.12Å; G73-A75 VanDerWaalsContact O-N 3.15Å; G73-A76 PolarHBondContact O-N 3.44Å; G73-A76 VanDerWaalsContact O-N 3.09Å; G73-G77 PolarHBondContact O-N 2.83Å; G73-Q445 CarbonylContact C-O 3.54Å; G73-Q445 WeakPolarHBondContact CA-O 3.21Å; G73-Q445 VanDerWaalsContact O-CB 3.29Å; G73-Q445 WeakPolarHBondContact O-CB 3.29Å
74	P	96	Very high	95.7	Very high	48 Å²	48	21.1 Å²	21.1	31%	0.312	12%	0.115	S	C	.	.	H	α-helix	trans	-51.2	-42.5	-179.3	-22.6	26.2	0	0	0	114.3	G77 H78 Q442 Q445	P74-G77 PolarHBondContact O-N 3.14Å; P74-H78 VanDerWaalsContact O-CG 3.24Å; P74-H78 PolarHBondContact O-N 2.71Å; P74-H78 PolarHBondContact O-ND1 3.15Å; P74-Q442 PolarHBondContact O-NE2 2.9Å; P74-Q445 WeakPolarHBondContact CD-O 3.43Å
75	A	95.8	Very high	95.7	Very high	5 Å²	5	24 Å²	24	4%	0.041	13%	0.13	C	C	.	.	H	α-helix	trans	-68.1	-43	180	0	0	0	0	0	112.6	F71 S72 G73 G77 H78 I79 E148 L152	F71-A75 HydrophobicContact CB-CB 4.29Å; F71-A75 HydrophobicContact CD2-CB 3.76Å; F71-A75 HydrophobicContact CG-CB 4.35Å; S72-A75 PolarHBondContact O-N 3.28Å; S72-A75 WeakPolarHBondContact OG-CB 3.47Å; S72-A75 PolarHBondContact OG-N 3.38Å; G73-A75 VanDerWaalsContact C-N 3.28Å; G73-A75 PolarHBondContact O-N 3.12Å; G73-A75 VanDerWaalsContact O-N 3.15Å; A75-G77 VanDerWaalsContact C-N 3.29Å; A75-G77 PolarHBondContact O-N 3.17Å; A75-H78 WeakPolarHBondContact O-CB 3.16Å; A75-H78 PolarHBondContact O-N 2.83Å; A75-H78 VanDerWaalsContact O-N 3.16Å; A75-I79 PolarHBondContact O-N 3.24Å; A75-E148 HydrophobicContact CB-CB 4.49Å; A75-E148 WeakPolarHBondContact CB-OE2 3.44Å; A75-L152 HydrophobicContact CB-CD1 4.1Å; A75-L152 HydrophobicContact CB-CD2 4.4Å; A75-L152 WeakPolarHBondContact O-CD2 2.9Å
76	A	96.9	Very high	95.7	Very high	1 Å²	1	25 Å²	25	1%	0.008	14%	0.136	C	C	.	.	H	α-helix	trans	-62.9	-38.3	173.4	0	0	0	0	0	111.6	L62 F65 K66 F71 S72 G73 H78 I79 F80	L62-A76 HydrophobicContact CD2-CB 4.09Å; F65-A76 HydrophobicContact CB-CB 4.1Å; K66-A76 HydrophobicContact CD-CB 4.22Å; K66-A76 HydrophobicContact CG-CB 3.65Å; F71-A76 HydrophobicContact CB-CB 4.39Å; S72-A76 PolarHBondContact O-N 3.46Å; G73-A76 PolarHBondContact O-N 3.44Å; G73-A76 VanDerWaalsContact O-N 3.09Å; A76-H78 VanDerWaalsContact C-N 3.33Å; A76-H78 PolarHBondContact O-N 3.44Å; A76-I79 PolarHBondContact O-N 2.51Å; A76-F80 PolarHBondContact O-N 3.5Å
77	G	97.3	Very high	95.7	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-58.3	-42.7	171.1	0	0	0	0	0	112.6	G73 P74 A75 I79 F80 L81 Q442	G73-G77 PolarHBondContact O-N 2.83Å; P74-G77 PolarHBondContact O-N 3.14Å; A75-G77 VanDerWaalsContact C-N 3.29Å; A75-G77 PolarHBondContact O-N 3.17Å; G77-I79 VanDerWaalsContact C-N 3.35Å; G77-I79 PolarHBondContact O-N 3.36Å; G77-F80 PolarHBondContact O-N 3.32Å; G77-L81 WeakPolarHBondContact O-CB 3.39Å; G77-L81 PolarHBondContact O-N 2.9Å; G77-Q442 PolarHBondContact O-OE1 3.46Å; G77-Q442 VanDerWaalsContact O-OE1 3.14Å
78	H	97.5	Very high	95.7	Very high	81 Å²	81	23.4 Å²	23.4	38%	0.375	13%	0.13	S	C	.	.	H	α-helix	trans	-61.9	-42	-178.5	-70.7	-19.1	0	0	0	112	P74 A75 A76 F80 L81 I82 L152 Q442	P74-H78 VanDerWaalsContact O-CG 3.24Å; P74-H78 PolarHBondContact O-N 2.71Å; P74-H78 PolarHBondContact O-ND1 3.15Å; A75-H78 WeakPolarHBondContact O-CB 3.16Å; A75-H78 PolarHBondContact O-N 2.83Å; A75-H78 VanDerWaalsContact O-N 3.16Å; A76-H78 VanDerWaalsContact C-N 3.33Å; A76-H78 PolarHBondContact O-N 3.44Å; H78-F80 VanDerWaalsContact C-N 3.34Å; H78-F80 PolarHBondContact O-N 3.4Å; H78-L81 PolarHBondContact O-N 2.62Å; H78-I82 WeakPolarHBondContact O-CB 3.5Å; H78-I82 WeakPolarHBondContact O-CD1 3.34Å; H78-I82 WeakPolarHBondContact O-CG1 3.38Å; H78-I82 PolarHBondContact O-N 2.99Å; H78-L152 HydrophobicContact CB-CD2 4.49Å; H78-Q442 VanDerWaalsContact CA-OE1 3.3Å; H78-Q442 PolarHBondContact CE1-NE2 3.16Å; H78-Q442 PolarHBondContact ND1-NE2 3.38Å; H78-Q442 VanDerWaalsContact ND1-NE2 3.14Å; H78-Q442 PolarHBondContact ND1-OE1 3.38Å
79	I	97.3	Very high	95.7	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-58.2	-47.5	175	-69.3	-63.2	0	0	0	111	L61 F65 A75 A76 G77 G83 L152 V159	L61-I79 HydrophobicContact CD1-CG2 4.4Å; L61-I79 HydrophobicContact CD2-CG2 4.07Å; L61-I79 HydrophobicContact CG-CG2 4.43Å; F65-I79 HydrophobicContact CD1-CG1 4.05Å; F65-I79 HydrophobicContact CE1-CB 4.47Å; F65-I79 HydrophobicContact CE1-CD1 4.16Å; F65-I79 HydrophobicContact CE1-CG1 3.71Å; F65-I79 HydrophobicContact CE1-CG2 4.26Å; F65-I79 HydrophobicContact CE2-CG2 4.1Å; F65-I79 HydrophobicContact CZ-CD1 4.49Å; F65-I79 HydrophobicContact CZ-CG1 4.21Å; F65-I79 HydrophobicContact CZ-CG2 3.95Å; A75-I79 PolarHBondContact O-N 3.24Å; A76-I79 PolarHBondContact O-N 2.51Å; G77-I79 VanDerWaalsContact C-N 3.35Å; G77-I79 PolarHBondContact O-N 3.36Å; I79-G83 PolarHBondContact O-N 3.18Å; I79-L152 HydrophobicContact CD1-CD2 3.48Å; I79-L152 VanDerWaalsContact CD1-CD2 3.48Å; I79-L152 HydrophobicContact CG1-CD2 3.44Å; I79-L152 VanDerWaalsContact CG1-CD2 3.44Å; I79-V159 HydrophobicContact CG2-CG2 4.11Å
80	F	97.5	Very high	95.6	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64	-43.7	178.6	-165.1	-78.6	0	0	0	111.5	W57 F58 L61 L62 A76 G77 H78 G83 Q84 T316 T437 V441	W57-F80 HydrophobicContact CZ2-CD2 4.4Å; W57-F80 AromaticContact NE1-CE2 3.72Å; F58-F80 HydrophobicContact CD1-CE2 4.38Å; F58-F80 HydrophobicContact CD1-CZ 4.05Å; F58-F80 AromaticContact CE1-CZ 3.97Å; F58-F80 HydrophobicContact CE1-CZ 3.97Å; L61-F80 HydrophobicContact CD2-CB 4.39Å; L61-F80 HydrophobicContact CD2-CD2 3.86Å; L62-F80 HydrophobicContact CD2-CB 4.44Å; A76-F80 PolarHBondContact O-N 3.5Å; G77-F80 PolarHBondContact O-N 3.32Å; H78-F80 VanDerWaalsContact C-N 3.34Å; H78-F80 PolarHBondContact O-N 3.4Å; F80-G83 PolarHBondContact O-N 3.16Å; F80-Q84 HydrophobicContact CD1-CG 3.7Å; F80-Q84 HydrophobicContact CE1-CG 3.47Å; F80-Q84 VanDerWaalsContact CE1-CG 3.47Å; F80-Q84 HydrophobicContact CZ-CG 4.48Å; F80-Q84 WeakPolarHBondContact O-CG 3.46Å; F80-Q84 PolarHBondContact O-N 3.36Å; F80-T316 HydrophobicContact CE2-CG2 3.99Å; F80-T316 HydrophobicContact CZ-CG2 4.4Å; F80-T437 HydrophobicContact CE1-CG2 4.1Å; F80-T437 HydrophobicContact CZ-CG2 4.45Å; F80-V441 HydrophobicContact CB-CG1 3.98Å; F80-V441 HydrophobicContact CD1-CB 3.85Å; F80-V441 HydrophobicContact CD1-CG1 3.68Å; F80-V441 HydrophobicContact CD1-CG2 4.05Å; F80-V441 HydrophobicContact CD2-CG1 4.36Å; F80-V441 HydrophobicContact CE1-CB 4.12Å; F80-V441 HydrophobicContact CE1-CG1 4.26Å; F80-V441 HydrophobicContact CE1-CG2 3.79Å; F80-V441 HydrophobicContact CG-CB 4.43Å; F80-V441 HydrophobicContact CG-CG1 3.75Å; F80-V441 HydrophobicContact CZ-CG2 4.24Å
81	L	98	Very high	95.5	Very high	33 Å²	33	23.2 Å²	23.2	17%	0.173	13%	0.131	C	C	.	.	H	α-helix	trans	-63.2	-44.7	179.4	177.4	63.5	0	0	0	112.3	G77 H78 G83 Q84 I85 V439 Q442	G77-L81 WeakPolarHBondContact O-CB 3.39Å; G77-L81 PolarHBondContact O-N 2.9Å; H78-L81 PolarHBondContact O-N 2.62Å; L81-G83 PolarHBondContact O-N 2.72Å; L81-Q84 PolarHBondContact O-N 3.25Å; L81-I85 HydrophobicContact CD1-CD1 3.83Å; L81-I85 HydrophobicContact CD1-CG1 4.02Å; L81-I85 HydrophobicContact CD2-CD1 4.39Å; L81-I85 HydrophobicContact CG-CD1 3.77Å; L81-I85 HydrophobicContact CG-CG1 4.35Å; L81-I85 WeakPolarHBondContact O-CG1 3.44Å; L81-I85 PolarHBondContact O-N 3.37Å; L81-V439 HydrophobicContact CD1-CG2 4.13Å; L81-Q442 HydrophobicContact CB-CB 4.44Å; L81-Q442 HydrophobicContact CD2-CB 4.15Å; L81-Q442 HydrophobicContact CD2-CG 4.09Å
82	I	98	Very high	95.1	Very high	50 Å²	50	25.8 Å²	25.8	26%	0.256	15%	0.148	S	C	.	.	H	α-helix	trans	-54.2	-46.4	173.9	-70.9	164.1	0	0	0	109	H78 Q84 I85 S86 A156 V159 V160	H78-I82 WeakPolarHBondContact O-CB 3.5Å; H78-I82 WeakPolarHBondContact O-CD1 3.34Å; H78-I82 WeakPolarHBondContact O-CG1 3.38Å; H78-I82 PolarHBondContact O-N 2.99Å; I82-Q84 PolarHBondContact O-N 3.07Å; I82-I85 PolarHBondContact O-N 3.33Å; I82-S86 WeakPolarHBondContact O-CB 3.44Å; I82-S86 PolarHBondContact O-N 3.26Å; I82-S86 PolarHBondContact O-OG 2.77Å; I82-A156 HydrophobicContact CD1-CB 4.07Å; I82-V159 HydrophobicContact CB-CG1 4.5Å; I82-V159 HydrophobicContact CG2-CB 4.42Å; I82-V159 HydrophobicContact CG2-CG1 4.02Å; I82-V160 HydrophobicContact CG2-CG2 3.96Å
83	G	97.5	Very high	94.8	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-58.7	-49.5	177	0	0	0	0	0	113.1	I79 F80 L81 I85 S86 D87 Q163	I79-G83 PolarHBondContact O-N 3.18Å; F80-G83 PolarHBondContact O-N 3.16Å; L81-G83 PolarHBondContact O-N 2.72Å; G83-I85 PolarHBondContact O-N 3.07Å; G83-S86 PolarHBondContact O-N 3.37Å; G83-D87 WeakPolarHBondContact O-CB 3.36Å; G83-D87 PolarHBondContact O-N 3.33Å; G83-Q163 VanDerWaalsContact O-CG 3.28Å; G83-Q163 WeakPolarHBondContact O-CG 3.38Å
84	Q	96.2	Very high	94.6	Very high	3 Å²	3	28.3 Å²	28.3	1%	0.014	16%	0.156	C	C	.	.	H	α-helix	trans	-63.9	-40.2	-179.8	-65.5	-60.1	-60.6	0	0	113.1	F80 L81 I82 A88 K434	F80-Q84 HydrophobicContact CD1-CG 3.7Å; F80-Q84 HydrophobicContact CE1-CG 3.47Å; F80-Q84 VanDerWaalsContact CE1-CG 3.47Å; F80-Q84 HydrophobicContact CZ-CG 4.48Å; F80-Q84 WeakPolarHBondContact O-CG 3.46Å; F80-Q84 PolarHBondContact O-N 3.36Å; L81-Q84 PolarHBondContact O-N 3.25Å; I82-Q84 PolarHBondContact O-N 3.07Å; Q84-A88 VanDerWaalsContact O-CB 3.27Å; Q84-A88 WeakPolarHBondContact O-CB 3.39Å; Q84-A88 PolarHBondContact O-N 2.87Å; Q84-K434 PolarHBondContact OE1-O 3.44Å
85	I	96.9	Very high	93.9	Very high	61 Å²	61	27 Å²	27	31%	0.313	15%	0.151	S	C	.	.	H	α-helix	trans	-64.7	-48	176.4	-68.5	170.9	0	0	0	110.1	L81 I82 G83 D87 A88 I89 M435	L81-I85 HydrophobicContact CD1-CD1 3.83Å; L81-I85 HydrophobicContact CD1-CG1 4.02Å; L81-I85 HydrophobicContact CD2-CD1 4.39Å; L81-I85 HydrophobicContact CG-CD1 3.77Å; L81-I85 HydrophobicContact CG-CG1 4.35Å; L81-I85 WeakPolarHBondContact O-CG1 3.44Å; L81-I85 PolarHBondContact O-N 3.37Å; I82-I85 PolarHBondContact O-N 3.33Å; G83-I85 PolarHBondContact O-N 3.07Å; I85-D87 VanDerWaalsContact C-N 3.3Å; I85-D87 PolarHBondContact O-N 3.01Å; I85-A88 PolarHBondContact O-N 3.41Å; I85-I89 HydrophobicContact CG2-CD1 3.79Å; I85-I89 WeakPolarHBondContact O-CG1 3.43Å; I85-I89 PolarHBondContact O-N 3.07Å; I85-M435 HydrophobicContact CG1-CE 4.39Å; I85-M435 HydrophobicContact CG1-SD 3.87Å
86	S	96.8	Very high	93.1	Very high	21 Å²	21	32.3 Å²	32.3	15%	0.147	17%	0.174	C	C	.	.	H	α-helix	trans	-58.9	-42.7	179	-66	0	0	0	0	111.8	I82 G83 I89 A90 V160	I82-S86 WeakPolarHBondContact O-CB 3.44Å; I82-S86 PolarHBondContact O-N 3.26Å; I82-S86 PolarHBondContact O-OG 2.77Å; G83-S86 PolarHBondContact O-N 3.37Å; S86-I89 PolarHBondContact O-N 3.04Å; S86-A90 WeakPolarHBondContact O-CB 3.26Å; S86-A90 PolarHBondContact O-N 3.14Å; S86-V160 WeakPolarHBondContact OG-CG2 3.34Å
87	D	94.4	Very high	92.3	Very high	10 Å²	10	36.8 Å²	36.8	5%	0.053	19%	0.194	C	C	.	.	H	α-helix	trans	-68.7	-41.1	178.4	-168	14.4	0	0	0	112.9	G83 I85 I89 A90 T91 Q163 K434	G83-D87 WeakPolarHBondContact O-CB 3.36Å; G83-D87 PolarHBondContact O-N 3.33Å; I85-D87 VanDerWaalsContact C-N 3.3Å; I85-D87 PolarHBondContact O-N 3.01Å; D87-I89 VanDerWaalsContact C-N 3.27Å; D87-I89 PolarHBondContact O-N 3.06Å; D87-A90 PolarHBondContact O-N 3.38Å; D87-T91 WeakPolarHBondContact O-CB 3.22Å; D87-T91 PolarHBondContact O-N 3.15Å; D87-T91 PolarHBondContact O-OG1 3.3Å; D87-T91 PolarHBondContact OD1-OG1 2.97Å; D87-Q163 HydrophobicContact CB-CB 4.18Å; D87-Q163 HydrophobicContact CB-CG 4.39Å; D87-Q163 VanDerWaalsContact CB-NE2 3.33Å; D87-K434 HydrophobicContact CB-CD 3.8Å; D87-K434 VanDerWaalsContact OD2-CD 3.3Å; D87-K434 WeakPolarHBondContact OD2-CD 3.37Å; D87-K434 WeakPolarHBondContact OD2-CE 3.13Å
88	A	93.7	Very high	91.1	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-60.2	-38	176.2	0	0	0	0	0	112	Q84 I85 P92 F431 K434 M435	Q84-A88 VanDerWaalsContact O-CB 3.27Å; Q84-A88 WeakPolarHBondContact O-CB 3.39Å; Q84-A88 PolarHBondContact O-N 2.87Å; I85-A88 PolarHBondContact O-N 3.41Å; A88-P92 WeakPolarHBondContact O-CD 3.25Å; A88-F431 HydrophobicContact CB-CD2 3.77Å; A88-F431 HydrophobicContact CB-CE2 4.14Å; A88-F431 HydrophobicContact CB-CG 4.48Å; A88-K434 HydrophobicContact CB-CB 4.02Å; A88-K434 HydrophobicContact CB-CD 4.24Å; A88-M435 HydrophobicContact CB-CG 4.31Å
89	I	93	Very high	89.8	Confident	90 Å²	90	37.7 Å²	37.7	46%	0.462	20%	0.202	S	C	.	.	H	α-helix	trans	-80.1	-42.8	177.3	-65.5	170.6	0	0	0	111.5	I85 S86 D87 T91 P92 I93	I85-I89 HydrophobicContact CG2-CD1 3.79Å; I85-I89 WeakPolarHBondContact O-CG1 3.43Å; I85-I89 PolarHBondContact O-N 3.07Å; S86-I89 PolarHBondContact O-N 3.04Å; D87-I89 VanDerWaalsContact C-N 3.27Å; D87-I89 PolarHBondContact O-N 3.06Å; I89-T91 VanDerWaalsContact C-N 3.34Å; I89-T91 PolarHBondContact O-N 2.98Å; I89-P92 WeakPolarHBondContact O-CD 3.45Å; I89-I93 HydrophobicContact CG2-CD1 3.61Å; I89-I93 WeakPolarHBondContact O-CG1 2.99Å; I89-I93 PolarHBondContact O-N 3.44Å
90	A	92.7	Very high	88.3	Confident	7 Å²	7	45.6 Å²	45.6	6%	0.058	23%	0.232	C	C	.	.	H	α-helix	trans	-64.7	-38.2	-177.2	0	0	0	0	0	111.9	S86 D87 I93 V94 L164 A167	S86-A90 WeakPolarHBondContact O-CB 3.26Å; S86-A90 PolarHBondContact O-N 3.14Å; D87-A90 PolarHBondContact O-N 3.38Å; A90-I93 PolarHBondContact O-N 2.91Å; A90-V94 VanDerWaalsContact O-CB 3.24Å; A90-V94 WeakPolarHBondContact O-CB 3.42Å; A90-V94 VanDerWaalsContact O-CG2 3.24Å; A90-V94 WeakPolarHBondContact O-CG2 3.14Å; A90-V94 PolarHBondContact O-N 3.46Å; A90-L164 HydrophobicContact CB-CD1 3.92Å; A90-A167 HydrophobicContact CB-CB 3.88Å
91	T	89.7	Confident	86.3	Confident	21 Å²	21	47 Å²	47	13%	0.129	24%	0.241	C	C	.	.	H	α-helix	trans	-56	-54	-177.4	-67.1	0	0	0	0	112.3	D87 I89 G95 I171	D87-T91 WeakPolarHBondContact O-CB 3.22Å; D87-T91 PolarHBondContact O-N 3.15Å; D87-T91 PolarHBondContact O-OG1 3.3Å; D87-T91 PolarHBondContact OD1-OG1 2.97Å; I89-T91 VanDerWaalsContact C-N 3.34Å; I89-T91 PolarHBondContact O-N 2.98Å; T91-G95 PolarHBondContact O-N 2.95Å; T91-I171 HydrophobicContact CG2-CD1 3.97Å; T91-I171 WeakPolarHBondContact O-CD1 3.27Å
92	P	85.5	Confident	84.3	Confident	62 Å²	62	49.1 Å²	49.1	40%	0.403	25%	0.252	S	S	.	.	H	α-helix	trans	-63.1	-41.4	174.8	-25.2	34.3	0	0	0	114.6	A88 I89 G95 F96	A88-P92 WeakPolarHBondContact O-CD 3.25Å; I89-P92 WeakPolarHBondContact O-CD 3.45Å; P92-G95 PolarHBondContact O-N 2.79Å; P92-F96 WeakPolarHBondContact O-CB 3.44Å; P92-F96 PolarHBondContact O-N 3.3Å
93	I	87.9	Confident	82	Confident	93 Å²	93	53.8 Å²	53.8	48%	0.477	28%	0.277	S	S	.	.	H	α-helix	trans	-61.9	-51.3	-178.5	-67.6	173.7	0	0	0	110	I89 A90 G95 F96 E97	I89-I93 HydrophobicContact CG2-CD1 3.61Å; I89-I93 WeakPolarHBondContact O-CG1 2.99Å; I89-I93 PolarHBondContact O-N 3.44Å; A90-I93 PolarHBondContact O-N 2.91Å; I93-G95 VanDerWaalsContact C-N 3.3Å; I93-G95 PolarHBondContact O-N 3.46Å; I93-F96 PolarHBondContact O-N 2.93Å; I93-E97 HydrophobicContact CG2-CG 4.47Å; I93-E97 WeakPolarHBondContact O-CG 3.25Å; I93-E97 PolarHBondContact O-N 3.25Å
94	V	87.2	Confident	80	Confident	8 Å²	8	61.9 Å²	61.9	5%	0.048	31%	0.309	C	S	.	.	H	α-helix	trans	-60.6	-41.6	177.2	166.3	0	0	0	0	110.6	A90 E97 S98 L116 L164 A167 I171	A90-V94 VanDerWaalsContact O-CB 3.24Å; A90-V94 WeakPolarHBondContact O-CB 3.42Å; A90-V94 VanDerWaalsContact O-CG2 3.24Å; A90-V94 WeakPolarHBondContact O-CG2 3.14Å; A90-V94 PolarHBondContact O-N 3.46Å; V94-E97 PolarHBondContact O-N 3.14Å; V94-S98 WeakPolarHBondContact O-CB 3.21Å; V94-S98 PolarHBondContact O-N 3.45Å; V94-L116 HydrophobicContact CG1-CD1 4.15Å; V94-L116 HydrophobicContact CG1-CD2 3.79Å; V94-L116 HydrophobicContact CG1-CG 4.33Å; V94-L164 HydrophobicContact CG2-CD1 3.9Å; V94-A167 HydrophobicContact CG2-CB 4.4Å; V94-I171 HydrophobicContact CB-CD1 3.9Å; V94-I171 HydrophobicContact CG1-CB 3.9Å; V94-I171 HydrophobicContact CG1-CD1 3.66Å; V94-I171 HydrophobicContact CG1-CG1 4.29Å; V94-I171 HydrophobicContact CG1-CG2 4.18Å
95	G	81.8	Confident	77.8	Confident	21 Å²	21	69.8 Å²	69.8	22%	0.216	35%	0.346	C	S	.	.	H	α-helix	trans	-58.1	-47.9	175	0	0	0	0	0	112.5	T91 P92 I93 S98 D99	T91-G95 PolarHBondContact O-N 2.95Å; P92-G95 PolarHBondContact O-N 2.79Å; I93-G95 VanDerWaalsContact C-N 3.3Å; I93-G95 PolarHBondContact O-N 3.46Å; G95-S98 WeakPolarHBondContact O-CB 3.4Å; G95-S98 PolarHBondContact O-N 2.98Å; G95-D99 PolarHBondContact O-N 2.9Å
96	F	79.7	Confident	75.7	Confident	117 Å²	117	72.5 Å²	72.5	51%	0.513	37%	0.365	S	S	.	.	H	α-helix	trans	-64.6	-45.5	178.7	-176	-101	0	0	0	112.7	P92 I93 S98 D99 R100	P92-F96 WeakPolarHBondContact O-CB 3.44Å; P92-F96 PolarHBondContact O-N 3.3Å; I93-F96 PolarHBondContact O-N 2.93Å; F96-S98 VanDerWaalsContact C-N 3.33Å; F96-S98 PolarHBondContact O-N 3.26Å; F96-D99 PolarHBondContact O-N 3.45Å; F96-R100 VanDerWaalsContact CE1-NH1 3.29Å
97	E	78.9	Confident	73.8	Confident	95 Å²	95	72.3 Å²	72.3	44%	0.444	36%	0.364	S	S	.	.	H	α-helix	trans	-66.2	-36.4	177.3	-70.6	-56.8	146.3	0	0	112	I93 V94 D99 R100 T101	I93-E97 HydrophobicContact CG2-CG 4.47Å; I93-E97 WeakPolarHBondContact O-CG 3.25Å; I93-E97 PolarHBondContact O-N 3.25Å; V94-E97 PolarHBondContact O-N 3.14Å; E97-D99 PolarHBondContact O-N 3.48Å; E97-R100 PolarHBondContact O-N 3.28Å; E97-T101 PolarHBondContact O-N 3Å; E97-T101 PolarHBondContact O-OG1 2.71Å
98	S	73.3	Confident	71.9	Confident	2 Å²	2	75 Å²	75	1%	0.014	38%	0.378	C	S	.	.	H	α-helix	trans	-57.6	-34.5	177.8	-156.8	0	0	0	0	112.2	V94 G95 F96 R112 R113 L116	V94-S98 WeakPolarHBondContact O-CB 3.21Å; V94-S98 PolarHBondContact O-N 3.45Å; G95-S98 WeakPolarHBondContact O-CB 3.4Å; G95-S98 PolarHBondContact O-N 2.98Å; F96-S98 VanDerWaalsContact C-N 3.33Å; F96-S98 PolarHBondContact O-N 3.26Å; S98-R112 VanDerWaalsContact O-CD 3.29Å; S98-R112 WeakPolarHBondContact O-CD 3.37Å; S98-R112 PolarHBondContact O-NE 2.9Å; S98-R113 PolarHBondContact O-NH1 3.49Å; S98-R113 PolarHBondContact OG-NH1 2.93Å; S98-L116 WeakPolarHBondContact OG-CD2 3.39Å
99	D	70	Confident	70.4	Confident	98 Å²	98	86.2 Å²	86.2	52%	0.524	42%	0.42	S	S	.	.	H	α-helix	trans	-82.4	-17.7	-179.6	-70.3	-19	0	0	0	113.7	G95 F96 E97 R112 R113	G95-D99 PolarHBondContact O-N 2.9Å; F96-D99 PolarHBondContact O-N 3.45Å; E97-D99 PolarHBondContact O-N 3.48Å; D99-R112 PolarHBondContact O-NH1 3.24Å; D99-R113 IonicContact OD1-CZ 2.88Å; D99-R113 IonicContact OD1-NH1 3.71Å; D99-R113 PolarHBondContact OD1-NH1 3.01Å; D99-R113 IonicContact OD1-NH2 3.71Å; D99-R113 PolarHBondContact OD1-NH2 3.38Å
100	R	65.8	Low	69.4	Low	165 Å²	165	86 Å²	86	62%	0.623	41%	0.414	S	S	*	.	H	α-helix	trans	-101.5	-11.5	-174.9	-133.2	179.9	-170.9	157.3	3.8	114.8	F96 E97 D102	F96-R100 VanDerWaalsContact CE1-NH1 3.29Å; E97-R100 PolarHBondContact O-N 3.28Å; R100-D102 PolarHBondContact O-N 2.95Å
101	T	56.4	Low	68.7	Low	31 Å²	31	86 Å²	86	19%	0.19	42%	0.415	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.3	53.2	-172.5	-44.5	0	0	0	0	112.5	E97 Y104 C107 R112	E97-T101 PolarHBondContact O-N 3Å; E97-T101 PolarHBondContact O-OG1 2.71Å; T101-Y104 HydrophobicContact CG2-CD2 4.08Å; T101-C107 HydrophobicContact CG2-CB 3.96Å; T101-C107 WeakPolarHBondContact CG2-SG 3.47Å; T101-R112 WeakPolarHBondContact O-CD 3.23Å
102	D	54.4	Low	68.3	Low	76 Å²	76	87.7 Å²	87.7	41%	0.406	42%	0.419	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.8	-23.1	171.1	-65	-11.1	0	0	0	110.7	R100 I108 R112	R100-D102 PolarHBondContact O-N 2.95Å; D102-I108 WeakPolarHBondContact O-CD1 3.5Å; D102-I108 WeakPolarHBondContact O-CG1 3.4Å; D102-R112 IonicContact OD1-CZ 3.3Å; D102-R112 IonicContact OD1-NH1 3.13Å; D102-R112 PolarHBondContact OD1-NH1 2.99Å
103	N	50.1	Low	68.2	Low	148 Å²	148	85.7 Å²	85.7	79%	0.791	40%	0.404	S	S	*	.	S	Bend	trans	-92	-13.3	-168.1	-70.4	-13.4	0	0	0	116.4	Q105	N103-Q105 PolarHBondContact O-N 3.37Å
104	Y	54.8	Low	68.2	Low	171 Å²	171	81.8 Å²	81.8	67%	0.671	38%	0.383	S	S	*	.			trans	-85.4	111.3	179.8	-82.2	-84.2	0	0	0	110.6	T101 V106 C107 I108	T101-Y104 HydrophobicContact CG2-CD2 4.08Å; Y104-V106 PolarHBondContact O-N 2.94Å; Y104-C107 WeakPolarHBondContact O-CA 3.42Å; Y104-C107 WeakPolarHBondContact O-CB 3.42Å; Y104-C107 PolarHBondContact O-N 2.95Å; Y104-I108 PolarHBondContact O-N 3.38Å
105	Q	50.1	Low	68.3	Low	169 Å²	169	81.9 Å²	81.9	79%	0.79	38%	0.384	S	S	*	.	H	α-helix	trans	-48.2	-31.6	179.7	-95.1	177.4	-13.9	0	0	115.1	N103 I108	N103-Q105 PolarHBondContact O-N 3.37Å; Q105-I108 PolarHBondContact O-N 2.88Å
106	V	54.6	Low	68.7	Low	117 Å²	117	82 Å²	82	71%	0.709	38%	0.38	S	S	*	.	H	α-helix	trans	-69.7	-40	176.2	-179.1	0	0	0	0	111.5	Y104 I108 Y110	Y104-V106 PolarHBondContact O-N 2.94Å; V106-I108 VanDerWaalsContact C-N 3.3Å; V106-I108 PolarHBondContact O-N 3.16Å; V106-Y110 PolarHBondContact O-N 2.87Å
107	C	56.8	Low	69.4	Low	18 Å²	18	76.5 Å²	76.5	12%	0.122	36%	0.356	C	S	.	.	H	α-helix	trans	-67	-33.6	176.4	-62	0	0	0	0	111.8	T101 Y104 R109 G111	T101-C107 HydrophobicContact CG2-CB 3.96Å; T101-C107 WeakPolarHBondContact CG2-SG 3.47Å; Y104-C107 WeakPolarHBondContact O-CA 3.42Å; Y104-C107 WeakPolarHBondContact O-CB 3.42Å; Y104-C107 PolarHBondContact O-N 2.95Å; C107-R109 VanDerWaalsContact C-N 3.32Å; C107-R109 PolarHBondContact O-N 3.49Å; C107-G111 CarbonylContact O-C 3.3Å; C107-G111 VanDerWaalsContact O-C 3.3Å; C107-G111 WeakPolarHBondContact O-CA 3.4Å; C107-G111 PolarHBondContact O-N 3.49Å
108	I	53.7	Low	70.2	Confident	66 Å²	66	74.9 Å²	74.9	34%	0.338	35%	0.349	S	S	.	.	H	α-helix	trans	-61.6	-35.2	-179.2	-68.1	179.1	0	0	0	112.5	D102 Y104 Q105 V106 R256	D102-I108 WeakPolarHBondContact O-CD1 3.5Å; D102-I108 WeakPolarHBondContact O-CG1 3.4Å; Y104-I108 PolarHBondContact O-N 3.38Å; Q105-I108 PolarHBondContact O-N 2.88Å; V106-I108 VanDerWaalsContact C-N 3.3Å; V106-I108 PolarHBondContact O-N 3.16Å; I108-R256 PolarHBondContact O-NE 2.99Å; I108-R256 PolarHBondContact O-NH2 2.87Å
109	R	63.1	Low	71.2	Confident	235 Å²	235	79.1 Å²	79.1	89%	0.887	37%	0.371	S	S	*	.	H	α-helix	trans	-91.1	-36.6	-178.9	-71.8	-172.9	-178.4	173.5	1.6	114	C107	C107-R109 VanDerWaalsContact C-N 3.32Å; C107-R109 PolarHBondContact O-N 3.49Å
110	Y	71.4	Confident	72.4	Confident	85 Å²	85	74.4 Å²	74.4	33%	0.333	35%	0.346	S	S	.	.	H	α-helix	trans	-86.8	-19	-175	-169	-113.4	0	0	0	113.7	V106 K114 L118 H249	V106-Y110 PolarHBondContact O-N 2.87Å; Y110-K114 HydrophobicContact CD1-CB 3.92Å; Y110-K114 HydrophobicContact CE1-CB 3.84Å; Y110-L118 HydrophobicContact CE1-CB 4.21Å; Y110-L118 HydrophobicContact CE1-CD2 3.89Å; Y110-H249 AromaticContact CE1-ND1 3.7Å; Y110-H249 AromaticContact CZ-ND1 3.59Å; Y110-H249 WeakPolarHBondContact OH-CB 3.28Å; Y110-H249 PolarHBondContact OH-ND1 3.12Å
111	G	77.5	Confident	74	Confident	9 Å²	9	66.7 Å²	66.7	9%	0.093	32%	0.317	C	S	.	.			trans	102.3	133.9	-170.4	0	0	0	0	0	110.7	C107 S115 E254	C107-G111 CarbonylContact O-C 3.3Å; C107-G111 VanDerWaalsContact O-C 3.3Å; C107-G111 WeakPolarHBondContact O-CA 3.4Å; C107-G111 PolarHBondContact O-N 3.49Å; G111-S115 VanDerWaalsContact O-CB 3.3Å; G111-S115 WeakPolarHBondContact O-CB 3.26Å; G111-S115 PolarHBondContact O-N 3.32Å; G111-S115 PolarHBondContact O-OG 3.32Å; G111-E254 WeakPolarHBondContact CA-OE1 2.97Å; G111-E254 WeakPolarHBondContact CA-OE2 3.43Å
112	R	81.7	Confident	75.9	Confident	55 Å²	55	69.8 Å²	69.8	21%	0.208	33%	0.332	C	S	.	.	H	α-helix	trans	-66.7	-49.8	-173.5	-179.2	176.1	63.5	171.8	4.6	110.5	S98 D99 T101 D102 S115 L116 E179 E254	S98-R112 VanDerWaalsContact O-CD 3.29Å; S98-R112 WeakPolarHBondContact O-CD 3.37Å; S98-R112 PolarHBondContact O-NE 2.9Å; D99-R112 PolarHBondContact O-NH1 3.24Å; T101-R112 WeakPolarHBondContact O-CD 3.23Å; D102-R112 IonicContact OD1-CZ 3.3Å; D102-R112 IonicContact OD1-NH1 3.13Å; D102-R112 PolarHBondContact OD1-NH1 2.99Å; R112-S115 PolarHBondContact O-N 3.46Å; R112-L116 PolarHBondContact O-N 3.01Å; R112-E179 IonicContact NH2-OE1 2.82Å; R112-E254 PolarHBondContact N-OE1 3.48Å; R112-E254 PolarHBondContact N-OE2 3.45Å
113	R	83.6	Confident	78	Confident	21 Å²	21	68.5 Å²	68.5	8%	0.079	33%	0.325	C	S	.	.	H	α-helix	trans	-70.7	-36.8	-178.3	-53.1	-53.2	-173.6	174	2.8	110.8	S98 D99 L116 H117 A175 L176 E179 E254	S98-R113 PolarHBondContact O-NH1 3.49Å; S98-R113 PolarHBondContact OG-NH1 2.93Å; D99-R113 IonicContact OD1-CZ 2.88Å; D99-R113 IonicContact OD1-NH1 3.71Å; D99-R113 PolarHBondContact OD1-NH1 3.01Å; D99-R113 IonicContact OD1-NH2 3.71Å; D99-R113 PolarHBondContact OD1-NH2 3.38Å; R113-L116 PolarHBondContact O-N 3.29Å; R113-H117 WeakPolarHBondContact O-CB 3.43Å; R113-H117 PolarHBondContact O-N 3.25Å; R113-A175 HydrophobicContact CG-CB 4.29Å; R113-L176 HydrophobicContact CB-CB 4.45Å; R113-L176 HydrophobicContact CB-CD1 4.4Å; R113-E179 WeakPolarHBondContact CG-OE1 3.24Å; R113-E179 VanDerWaalsContact CG-OE2 3.23Å; R113-E179 WeakPolarHBondContact CG-OE2 3.38Å; R113-E179 IonicContact CZ-OE1 3.69Å; R113-E179 IonicContact NE-OE1 3.7Å; R113-E179 PolarHBondContact NE-OE1 3.39Å; R113-E179 IonicContact NH2-OE1 3.72Å; R113-E254 PolarHBondContact N-OE1 2.99Å; R113-E254 PolarHBondContact N-OE2 3.49Å
114	K	88.2	Confident	80.3	Confident	11 Å²	11	61.4 Å²	61.4	5%	0.048	29%	0.287	C	S	.	.	H	α-helix	trans	-64.9	-37.4	172.5	-74.2	-171.6	69.5	-177	0	113.5	Y110 H117 L118 H249 I252 E254	Y110-K114 HydrophobicContact CD1-CB 3.92Å; Y110-K114 HydrophobicContact CE1-CB 3.84Å; K114-H117 WeakPolarHBondContact O-CB 3.29Å; K114-H117 PolarHBondContact O-N 3.33Å; K114-L118 WeakPolarHBondContact O-CB 3.49Å; K114-L118 PolarHBondContact O-N 3.15Å; K114-H249 PolarHBondContact NZ-O 3.5Å; K114-H249 PolarHBondContact O-CE1 3.48Å; K114-I252 PolarHBondContact NZ-O 2.9Å; K114-E254 HydrophobicContact CD-CB 4.11Å; K114-E254 HydrophobicContact CG-CB 4.41Å; K114-E254 PolarHBondContact N-OE2 3.18Å
115	S	89.4	Confident	82.4	Confident	9 Å²	9	58 Å²	58	6%	0.063	28%	0.276	C	S	.	.	H	α-helix	trans	-65.2	-43.5	178.6	-61.2	0	0	0	0	111	G111 R112 H117 L118 I119	G111-S115 VanDerWaalsContact O-CB 3.3Å; G111-S115 WeakPolarHBondContact O-CB 3.26Å; G111-S115 PolarHBondContact O-N 3.32Å; G111-S115 PolarHBondContact O-OG 3.32Å; R112-S115 PolarHBondContact O-N 3.46Å; S115-H117 PolarHBondContact O-N 3.09Å; S115-L118 PolarHBondContact O-N 2.9Å; S115-I119 WeakPolarHBondContact O-CG1 3.45Å; S115-I119 PolarHBondContact O-N 2.68Å
116	L	90.1	Very high	84.6	Confident	25 Å²	25	52.5 Å²	52.5	13%	0.131	26%	0.259	C	S	.	.	H	α-helix	trans	-61.6	-43.7	174.4	-176.4	62.1	0	0	0	112.3	V94 S98 R112 R113 L118 I119 G120	V94-L116 HydrophobicContact CG1-CD1 4.15Å; V94-L116 HydrophobicContact CG1-CD2 3.79Å; V94-L116 HydrophobicContact CG1-CG 4.33Å; S98-L116 WeakPolarHBondContact OG-CD2 3.39Å; R112-L116 PolarHBondContact O-N 3.01Å; R113-L116 PolarHBondContact O-N 3.29Å; L116-L118 VanDerWaalsContact C-N 3.31Å; L116-L118 PolarHBondContact O-N 3.03Å; L116-I119 PolarHBondContact O-N 2.81Å; L116-G120 PolarHBondContact O-N 3.48Å
117	H	94	Very high	86.7	Confident	1 Å²	1	47 Å²	47	1%	0.005	23%	0.226	C	C	.	.	H	α-helix	trans	-59.5	-41.7	174.9	-174.9	-79	0	0	0	112.4	G46 R113 K114 S115 G120 T121 F248 H249	G46-H117 PolarHBondContact O-NE2 2.06Å; R113-H117 WeakPolarHBondContact O-CB 3.43Å; R113-H117 PolarHBondContact O-N 3.25Å; K114-H117 WeakPolarHBondContact O-CB 3.29Å; K114-H117 PolarHBondContact O-N 3.33Å; S115-H117 PolarHBondContact O-N 3.09Å; H117-G120 PolarHBondContact O-N 2.82Å; H117-T121 WeakPolarHBondContact O-CB 3.5Å; H117-T121 PolarHBondContact O-N 3.46Å; H117-T121 PolarHBondContact O-OG1 2.72Å; H117-F248 HydrophobicContact CB-CE1 4.42Å; H117-F248 AromaticContact CD2-CE1 3.86Å; H117-F248 AromaticContact CE1-CD1 3.57Å; H117-F248 AromaticContact CE1-CE1 3.65Å; H117-F248 AromaticContact CG-CE1 3.72Å; H117-F248 AromaticContact ND1-CD1 3.79Å; H117-F248 AromaticContact ND1-CE1 3.57Å; H117-F248 AromaticContact NE2-CE1 3.8Å; H117-H249 AromaticContact CE1-NE2 3.79Å; H117-H249 AromaticContact ND1-CD2 3.97Å; H117-H249 AromaticContact ND1-CE1 3.48Å; H117-H249 PolarHBondContact ND1-CE1 3.09Å; H117-H249 AromaticContact ND1-NE2 2.98Å; H117-H249 PolarHBondContact ND1-NE2 3.32Å
118	L	94.8	Very high	88.7	Confident	60 Å²	60	46.1 Å²	46.1	31%	0.314	22%	0.22	S	C	.	.	H	α-helix	trans	-66.7	-46.5	178.9	-179.2	61	0	0	0	111.5	Y110 K114 S115 L116 G120 T121 L122	Y110-L118 HydrophobicContact CE1-CB 4.21Å; Y110-L118 HydrophobicContact CE1-CD2 3.89Å; K114-L118 WeakPolarHBondContact O-CB 3.49Å; K114-L118 PolarHBondContact O-N 3.15Å; S115-L118 PolarHBondContact O-N 2.9Å; L116-L118 VanDerWaalsContact C-N 3.31Å; L116-L118 PolarHBondContact O-N 3.03Å; L118-G120 VanDerWaalsContact C-N 3.29Å; L118-G120 PolarHBondContact O-N 3.42Å; L118-T121 WeakPolarHBondContact O-CB 3.35Å; L118-T121 PolarHBondContact O-N 2.96Å; L118-L122 HydrophobicContact CG-CD1 4.39Å; L118-L122 WeakPolarHBondContact O-CG 3.28Å; L118-L122 PolarHBondContact O-N 3.22Å
119	I	94.3	Very high	90.7	Very high	91 Å²	91	43.1 Å²	43.1	47%	0.467	21%	0.205	S	C	.	.	H	α-helix	trans	-55.9	-48.9	174.8	-68.4	166	0	0	0	109.4	S115 L116 T121 L122 L123	S115-I119 WeakPolarHBondContact O-CG1 3.45Å; S115-I119 PolarHBondContact O-N 2.68Å; L116-I119 PolarHBondContact O-N 2.81Å; I119-T121 VanDerWaalsContact C-N 3.34Å; I119-T121 PolarHBondContact O-N 2.95Å; I119-L122 PolarHBondContact O-N 2.96Å; I119-L123 HydrophobicContact CG2-CD1 4.34Å; I119-L123 WeakPolarHBondContact O-CG 3.31Å; I119-L123 PolarHBondContact O-N 3Å
120	G	96.5	Very high	92.3	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-58	-44.8	177.2	0	0	0	0	0	113.1	L116 H117 L118 L122 L123 V124 G165	L116-G120 PolarHBondContact O-N 3.48Å; H117-G120 PolarHBondContact O-N 2.82Å; L118-G120 VanDerWaalsContact C-N 3.29Å; L118-G120 PolarHBondContact O-N 3.42Å; G120-L122 VanDerWaalsContact C-N 3.32Å; G120-L122 PolarHBondContact O-N 3.25Å; G120-L123 PolarHBondContact O-N 3.28Å; G120-V124 WeakPolarHBondContact O-CG2 3.5Å; G120-V124 PolarHBondContact O-N 3.39Å; G120-G165 WeakPolarHBondContact CA-O 3.07Å; G120-G165 WeakPolarHBondContact O-CA 3.45Å
121	T	97.9	Very high	93.5	Very high	3 Å²	3	30.6 Å²	30.6	2%	0.018	16%	0.159	C	C	.	.	H	α-helix	trans	-59.1	-42.7	177.5	-63	0	0	0	0	111.7	Y49 H117 L118 I119 V124 F125 L242	Y49-T121 HydrophobicContact CD1-CG2 4.13Å; Y49-T121 HydrophobicContact CE1-CG2 4.25Å; H117-T121 WeakPolarHBondContact O-CB 3.5Å; H117-T121 PolarHBondContact O-N 3.46Å; H117-T121 PolarHBondContact O-OG1 2.72Å; L118-T121 WeakPolarHBondContact O-CB 3.35Å; L118-T121 PolarHBondContact O-N 2.96Å; I119-T121 VanDerWaalsContact C-N 3.34Å; I119-T121 PolarHBondContact O-N 2.95Å; T121-V124 PolarHBondContact O-N 3.3Å; T121-F125 WeakPolarHBondContact O-CB 3.34Å; T121-F125 PolarHBondContact O-N 3.46Å; T121-L242 HydrophobicContact CG2-CD1 4.17Å
122	L	97.9	Very high	94.4	Very high	96 Å²	96	30.1 Å²	30.1	50%	0.503	15%	0.154	S	C	.	.	H	α-helix	trans	-66.6	-39.6	177.9	-67.9	172	0	0	0	112.1	L118 I119 G120 F125 A126	L118-L122 HydrophobicContact CG-CD1 4.39Å; L118-L122 WeakPolarHBondContact O-CG 3.28Å; L118-L122 PolarHBondContact O-N 3.22Å; I119-L122 PolarHBondContact O-N 2.96Å; G120-L122 VanDerWaalsContact C-N 3.32Å; G120-L122 PolarHBondContact O-N 3.25Å; L122-F125 PolarHBondContact O-N 2.8Å; L122-A126 WeakPolarHBondContact O-CB 3.49Å; L122-A126 PolarHBondContact O-N 3.38Å
123	L	98.2	Very high	95.1	Very high	48 Å²	48	29.1 Å²	29.1	25%	0.251	15%	0.152	S	C	.	.	H	α-helix	trans	-63.9	-44.5	175.1	-66.2	-179.2	0	0	0	111.6	I119 G120 A126 S127 I161 L164	I119-L123 HydrophobicContact CG2-CD1 4.34Å; I119-L123 WeakPolarHBondContact O-CG 3.31Å; I119-L123 PolarHBondContact O-N 3Å; G120-L123 PolarHBondContact O-N 3.28Å; L123-A126 PolarHBondContact O-N 3.48Å; L123-S127 WeakPolarHBondContact O-CB 3.32Å; L123-S127 PolarHBondContact O-N 2.89Å; L123-S127 PolarHBondContact O-OG 3.14Å; L123-I161 HydrophobicContact CB-CG2 4.04Å; L123-I161 HydrophobicContact CD2-CG2 4.08Å; L123-L164 HydrophobicContact CD1-CB 4.34Å; L123-L164 HydrophobicContact CD1-CD2 3.88Å; L123-L164 HydrophobicContact CD1-CG 3.84Å
124	V	98.4	Very high	95.6	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-62	-45.8	175.6	177.5	0	0	0	0	110.5	Y49 G120 T121 A126 S127 F128 F162	Y49-V124 HydrophobicContact CD1-CG1 4.37Å; Y49-V124 HydrophobicContact CD2-CG1 4.4Å; Y49-V124 HydrophobicContact CE1-CB 4.13Å; Y49-V124 HydrophobicContact CE1-CG1 3.81Å; Y49-V124 HydrophobicContact CE2-CG1 3.84Å; G120-V124 WeakPolarHBondContact O-CG2 3.5Å; G120-V124 PolarHBondContact O-N 3.39Å; T121-V124 PolarHBondContact O-N 3.3Å; V124-A126 VanDerWaalsContact C-N 3.33Å; V124-A126 PolarHBondContact O-N 2.9Å; V124-S127 PolarHBondContact O-N 2.89Å; V124-S127 VanDerWaalsContact O-N 3.15Å; V124-S127 PolarHBondContact O-OG 3.3Å; V124-F128 HydrophobicContact CG1-CB 3.98Å; V124-F128 VanDerWaalsContact O-CB 3.32Å; V124-F128 WeakPolarHBondContact O-CB 3.35Å; V124-F128 PolarHBondContact O-N 3.14Å; V124-F162 HydrophobicContact CG1-CD2 4.03Å; V124-F162 HydrophobicContact CG1-CE2 4Å; V124-F162 HydrophobicContact CG2-CD2 4.23Å; V124-F162 HydrophobicContact CG2-CE2 4.44Å
125	F	98.3	Very high	95.8	Very high	99 Å²	99	32.6 Å²	32.6	43%	0.434	17%	0.166	S	C	.	.	H	α-helix	trans	-56.9	-42.5	175.7	175	-100.2	0	0	0	113.2	Y49 T121 L122 S127 T238 L242	Y49-F125 VanDerWaalsContact OH-CA 3.3Å; Y49-F125 WeakPolarHBondContact OH-CA 3.22Å; Y49-F125 PolarHBondContact OH-N 3.03Å; T121-F125 WeakPolarHBondContact O-CB 3.34Å; T121-F125 PolarHBondContact O-N 3.46Å; L122-F125 PolarHBondContact O-N 2.8Å; F125-S127 PolarHBondContact O-N 3.24Å; F125-T238 HydrophobicContact CD2-CG2 3.61Å; F125-T238 HydrophobicContact CE2-CG2 4Å; F125-L242 HydrophobicContact CD2-CD2 4.03Å; F125-L242 HydrophobicContact CE2-CD2 3.96Å
126	A	97.4	Very high	95.8	Very high	54 Å²	54	38.4 Å²	38.4	45%	0.446	19%	0.19	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-6.6	-179.2	0	0	0	0	0	114.3	L122 L123 V124 F130	L122-A126 WeakPolarHBondContact O-CB 3.49Å; L122-A126 PolarHBondContact O-N 3.38Å; L123-A126 PolarHBondContact O-N 3.48Å; V124-A126 VanDerWaalsContact C-N 3.33Å; V124-A126 PolarHBondContact O-N 2.9Å; A126-F130 WeakPolarHBondContact O-CD2 3.45Å; A126-F130 WeakPolarHBondContact O-CE2 3.45Å
127	S	98	Very high	95.7	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.224	C	C	.	.	T	Hydrogen-bonded Turn	trans	-129.8	-43.6	-170.2	56.3	0	0	0	0	115.1	L123 V124 F125 A129 F130 F158 F162	L123-S127 WeakPolarHBondContact O-CB 3.32Å; L123-S127 PolarHBondContact O-N 2.89Å; L123-S127 PolarHBondContact O-OG 3.14Å; V124-S127 PolarHBondContact O-N 2.89Å; V124-S127 VanDerWaalsContact O-N 3.15Å; V124-S127 PolarHBondContact O-OG 3.3Å; F125-S127 PolarHBondContact O-N 3.24Å; S127-A129 PolarHBondContact O-N 3.27Å; S127-F130 WeakPolarHBondContact O-CB 3.19Å; S127-F130 PolarHBondContact O-N 3.42Å; S127-F158 WeakPolarHBondContact CB-O 3.28Å; S127-F162 VanDerWaalsContact OG-CA 3.27Å; S127-F162 WeakPolarHBondContact OG-CA 3.48Å; S127-F162 WeakPolarHBondContact OG-CB 3.41Å; S127-F162 PolarHBondContact OG-N 3.17Å
128	F	98.1	Very high	95.5	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-63.5	-47.7	-163.6	179	-101.7	0	0	0	113.7	C53 M56 V124 F130 L131 F132 F162 V237	C53-F128 HydrophobicContact CB-CD1 4.48Å; C53-F128 HydrophobicContact CB-CD2 3.78Å; C53-F128 HydrophobicContact CB-CE1 4.23Å; C53-F128 HydrophobicContact CB-CE2 3.47Å; C53-F128 VanDerWaalsContact CB-CE2 3.47Å; C53-F128 HydrophobicContact CB-CG 4.27Å; C53-F128 HydrophobicContact CB-CZ 3.73Å; C53-F128 WeakPolarHBondContact SG-CD1 3.49Å; C53-F128 VanDerWaalsContact SG-CE1 3.59Å; C53-F128 VanDerWaalsContact SG-CG 3.55Å; M56-F128 HydrophobicContact CB-CZ 3.87Å; M56-F128 HydrophobicContact CG-CZ 4.21Å; M56-F128 HydrophobicContact SD-CE1 3.83Å; M56-F128 HydrophobicContact SD-CZ 3.7Å; V124-F128 HydrophobicContact CG1-CB 3.98Å; V124-F128 VanDerWaalsContact O-CB 3.32Å; V124-F128 WeakPolarHBondContact O-CB 3.35Å; V124-F128 PolarHBondContact O-N 3.14Å; F128-F130 PolarHBondContact O-N 3.05Å; F128-L131 HydrophobicContact CD2-CD1 4.3Å; F128-L131 VanDerWaalsContact O-CB 3.31Å; F128-L131 WeakPolarHBondContact O-CB 3.03Å; F128-L131 PolarHBondContact O-N 3.39Å; F128-F132 HydrophobicContact CE2-CD2 4.46Å; F128-F132 AromaticContact CE2-CE2 3.91Å; F128-F132 HydrophobicContact CE2-CE2 3.91Å; F128-F132 HydrophobicContact CZ-CD2 4.15Å; F128-F132 AromaticContact CZ-CE2 3.79Å; F128-F132 HydrophobicContact CZ-CE2 3.79Å; F128-F162 HydrophobicContact CB-CD2 3.95Å; F128-F162 HydrophobicContact CB-CE2 4.23Å; F128-F162 AromaticContact CD2-CD2 3.75Å; F128-F162 HydrophobicContact CD2-CD2 3.75Å; F128-F162 HydrophobicContact CD2-CE1 4.36Å; F128-F162 AromaticContact CD2-CE2 3.39Å; F128-F162 HydrophobicContact CD2-CE2 3.39Å; F128-F162 HydrophobicContact CD2-CG 4.38Å; F128-F162 AromaticContact CD2-CZ 3.73Å; F128-F162 HydrophobicContact CD2-CZ 3.73Å; F128-F162 HydrophobicContact CE2-CE2 4.13Å; F128-F162 HydrophobicContact CE2-CZ 4.06Å; F128-F162 HydrophobicContact CG-CD2 4.29Å; F128-F162 HydrophobicContact CG-CE2 4.13Å; F128-V237 HydrophobicContact CD1-CG1 4.33Å; F128-V237 HydrophobicContact CE1-CB 4.39Å; F128-V237 HydrophobicContact CE1-CG1 3.67Å; F128-V237 HydrophobicContact CZ-CG1 4.43Å
129	A	95.9	Very high	95.2	Very high	3 Å²	3	42.6 Å²	42.6	3%	0.025	24%	0.237	C	C	.	.	H	α-helix	trans	-57.6	-36.7	-179.5	0	0	0	0	0	112.1	S127 L131 F132 M133 F235	S127-A129 PolarHBondContact O-N 3.27Å; A129-L131 PolarHBondContact O-N 2.86Å; A129-F132 PolarHBondContact O-N 3.01Å; A129-M133 WeakPolarHBondContact O-CG 3.31Å; A129-F235 HydrophobicContact CB-CD1 3.95Å; A129-F235 HydrophobicContact CB-CE1 3.96Å
130	F	96	Very high	94.7	Very high	57 Å²	57	40.8 Å²	40.8	25%	0.25	22%	0.224	C	C	.	.	H	α-helix	trans	-67	-20.5	-179.9	-59.8	-73.8	0	0	0	113.4	A126 S127 F128 F132 M133 F136 F158	A126-F130 WeakPolarHBondContact O-CD2 3.45Å; A126-F130 WeakPolarHBondContact O-CE2 3.45Å; S127-F130 WeakPolarHBondContact O-CB 3.19Å; S127-F130 PolarHBondContact O-N 3.42Å; F128-F130 PolarHBondContact O-N 3.05Å; F130-F132 VanDerWaalsContact C-N 3.26Å; F130-F132 PolarHBondContact O-N 3.24Å; F130-M133 HydrophobicContact CD1-SD 3.92Å; F130-M133 HydrophobicContact CE1-SD 4.41Å; F130-M133 PolarHBondContact O-N 3.49Å; F130-F136 HydrophobicContact CD1-CE2 4.12Å; F130-F136 HydrophobicContact CD1-CZ 4.29Å; F130-F136 HydrophobicContact CE1-CE2 4.07Å; F130-F136 HydrophobicContact CE1-CZ 4.1Å; F130-F158 HydrophobicContact CB-CD1 3.97Å; F130-F158 HydrophobicContact CB-CD2 4.4Å; F130-F158 HydrophobicContact CB-CE1 4.01Å; F130-F158 HydrophobicContact CB-CE2 4.45Å; F130-F158 HydrophobicContact CB-CG 4.16Å; F130-F158 HydrophobicContact CB-CZ 4.25Å; F130-F158 HydrophobicContact CD2-CD1 4.14Å; F130-F158 AromaticContact CD2-CE1 3.87Å; F130-F158 HydrophobicContact CD2-CE1 3.87Å; F130-F158 HydrophobicContact CG-CD1 4.29Å; F130-F158 AromaticContact CG-CE1 3.95Å; F130-F158 HydrophobicContact CG-CE1 3.95Å; F130-F158 HydrophobicContact CG-CZ 4.32Å
131	L	96.9	Very high	93.6	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-68.9	-25.4	176.1	-61.7	178.4	0	0	0	113	W57 F64 F128 A129 F158 V159 F162	W57-L131 HydrophobicContact CE3-CD1 4.38Å; W57-L131 HydrophobicContact CZ3-CD1 4.14Å; F64-L131 WeakPolarHBondContact CE1-O 3.47Å; F128-L131 HydrophobicContact CD2-CD1 4.3Å; F128-L131 VanDerWaalsContact O-CB 3.31Å; F128-L131 WeakPolarHBondContact O-CB 3.03Å; F128-L131 PolarHBondContact O-N 3.39Å; A129-L131 PolarHBondContact O-N 2.86Å; L131-F158 HydrophobicContact CD2-CB 3.67Å; L131-F158 HydrophobicContact CG-CB 4.46Å; L131-V159 HydrophobicContact CD2-CB 4.47Å; L131-V159 HydrophobicContact CD2-CG2 3.53Å; L131-F162 HydrophobicContact CD1-CB 4.17Å; L131-F162 HydrophobicContact CD1-CD1 3.94Å; L131-F162 HydrophobicContact CD1-CG 4.05Å
132	F	97.1	Very high	92.2	Very high	0 Å²	0	50.8 Å²	50.8	0%	0	30%	0.301	C	S	.	.	T	Hydrogen-bonded Turn	trans	-108.2	22.1	179.5	-69.2	-82.1	0	0	0	112.3	M56 L61 F64 F128 A129 F130 F230 S231	M56-F132 HydrophobicContact CB-CE2 3.91Å; M56-F132 HydrophobicContact CB-CZ 3.8Å; M56-F132 HydrophobicContact CE-CB 4.47Å; M56-F132 HydrophobicContact CE-CD1 3.91Å; M56-F132 HydrophobicContact CE-CD2 3.77Å; M56-F132 HydrophobicContact CE-CE1 4.04Å; M56-F132 HydrophobicContact CE-CE2 3.91Å; M56-F132 HydrophobicContact CE-CG 3.77Å; M56-F132 HydrophobicContact CE-CZ 4.05Å; M56-F132 HydrophobicContact SD-CE2 4.42Å; L61-F132 HydrophobicContact CD1-CZ 4.36Å; F64-F132 HydrophobicContact CB-CD1 4.01Å; F64-F132 HydrophobicContact CB-CE1 4.08Å; F64-F132 HydrophobicContact CD1-CD1 4.22Å; F64-F132 HydrophobicContact CD2-CD1 4.23Å; F64-F132 WeakPolarHBondContact CE2-O 3.3Å; F64-F132 AromaticContact CG-CD1 3.91Å; F64-F132 HydrophobicContact CG-CD1 3.91Å; F64-F132 HydrophobicContact CG-CE1 4.45Å; F64-F132 WeakPolarHBondContact CZ-O 3.29Å; F128-F132 HydrophobicContact CE2-CD2 4.46Å; F128-F132 AromaticContact CE2-CE2 3.91Å; F128-F132 HydrophobicContact CE2-CE2 3.91Å; F128-F132 HydrophobicContact CZ-CD2 4.15Å; F128-F132 AromaticContact CZ-CE2 3.79Å; F128-F132 HydrophobicContact CZ-CE2 3.79Å; A129-F132 PolarHBondContact O-N 3.01Å; F130-F132 VanDerWaalsContact C-N 3.26Å; F130-F132 PolarHBondContact O-N 3.24Å; F132-F230 HydrophobicContact CB-CB 4.49Å; F132-F230 HydrophobicContact CD1-CB 4.44Å; F132-F230 HydrophobicContact CD1-CD1 4.28Å; F132-S231 VanDerWaalsContact O-CA 3.24Å; F132-S231 WeakPolarHBondContact O-CA 3.26Å; F132-S231 VanDerWaalsContact O-CB 3.25Å; F132-S231 WeakPolarHBondContact O-CB 3.28Å; F132-S231 PolarHBondContact O-N 3.23Å
133	M	95.4	Very high	91.1	Very high	34 Å²	34	48.9 Å²	48.9	17%	0.167	30%	0.304	C	S	.	.	S	Bend	trans	-111.9	157.4	172.9	-68.5	179	76.1	0	0	110.2	A129 F130 F136 Y155 F235	A129-M133 WeakPolarHBondContact O-CG 3.31Å; F130-M133 HydrophobicContact CD1-SD 3.92Å; F130-M133 HydrophobicContact CE1-SD 4.41Å; F130-M133 PolarHBondContact O-N 3.49Å; M133-F136 HydrophobicContact CE-CE1 4.45Å; M133-F136 HydrophobicContact CE-CZ 4.35Å; M133-Y155 WeakPolarHBondContact O-CE1 3.45Å; M133-Y155 PolarHBondContact O-OH 3.14Å; M133-F235 HydrophobicContact CE-CE2 3.9Å; M133-F235 HydrophobicContact CE-CZ 3.81Å; M133-F235 HydrophobicContact CG-CE2 4.26Å; M133-F235 HydrophobicContact SD-CE1 4.41Å; M133-F235 HydrophobicContact SD-CE2 3.62Å; M133-F235 HydrophobicContact SD-CZ 3.37Å; M133-F235 WeakPolarHBondContact SD-CZ 3.4Å
134	R	94.5	Very high	90.3	Very high	100 Å²	100	57.2 Å²	57.2	38%	0.377	33%	0.332	S	S	.	.	P	Polyproline II helix	trans	-68.4	145.7	164.9	-69.9	-179.7	178.4	-178	1.9	109.4	L69 Y140 P224 A227	L69-R134 HydrophobicContact CD2-CG 3.89Å; R134-Y140 HydrophobicContact CB-CE2 3.89Å; R134-Y140 HydrophobicContact CG-CE2 3.98Å; R134-P224 PolarHBondContact NH2-O 3.5Å; R134-A227 HydrophobicContact CG-CB 4.28Å
135	C	92.3	Very high	89.7	Confident	5 Å²	5	60.1 Å²	60.1	3%	0.034	35%	0.352	C	S	.	.	P	Polyproline II helix	trans	-66.9	140.5	179.8	50.2	0	0	0	0	111.6	G137 C138 Y140 Q151 Y154 Y155	C135-G137 PolarHBondContact O-N 3.12Å; C135-C138 HydrophobicContact CB-CB 4.18Å; C135-C138 WeakPolarHBondContact CB-SG 3.22Å; C135-C138 WeakPolarHBondContact O-CB 3.21Å; C135-C138 PolarHBondContact O-N 3.45Å; C135-C138 WeakPolarHBondContact SG-CB 3.27Å; C135-C138 CovalentContact SG-SG 2.02Å; C135-C138 PolarHBondContact SG-SG 3.2Å; C135-Y140 PolarHBondContact N-OH 3.47Å; C135-Y140 PolarHBondContact SG-OH 2.99Å; C135-Q151 VanDerWaalsContact SG-CG 3.57Å; C135-Q151 PolarHBondContact SG-OE1 3.21Å; C135-Y154 HydrophobicContact CB-CD1 3.29Å; C135-Y154 HydrophobicContact CB-CD2 4.13Å; C135-Y154 HydrophobicContact CB-CE1 3.42Å; C135-Y154 VanDerWaalsContact CB-CE1 3.42Å; C135-Y154 HydrophobicContact CB-CE2 4.24Å; C135-Y154 HydrophobicContact CB-CG 3.67Å; C135-Y155 HydrophobicContact CB-CE2 4.3Å; C135-Y155 PolarHBondContact N-OH 3.23Å
136	F	90.8	Very high	89.4	Confident	130 Å²	130	56.6 Å²	56.6	57%	0.57	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63	131.8	-178.7	-66.2	-57.3	0	0	0	111.2	F130 M133 C138 Y154	F130-F136 HydrophobicContact CD1-CE2 4.12Å; F130-F136 HydrophobicContact CD1-CZ 4.29Å; F130-F136 HydrophobicContact CE1-CE2 4.07Å; F130-F136 HydrophobicContact CE1-CZ 4.1Å; M133-F136 HydrophobicContact CE-CE1 4.45Å; M133-F136 HydrophobicContact CE-CZ 4.35Å; F136-C138 PolarHBondContact O-N 3.41Å; F136-Y154 HydrophobicContact CB-CE2 4.38Å; F136-Y154 HydrophobicContact CD2-CE2 4.1Å; F136-Y154 AromaticContact CD2-CZ 3.98Å; F136-Y154 WeakPolarHBondContact CD2-OH 3.5Å; F136-Y154 WeakPolarHBondContact CE2-OH 3.35Å
137	G	87.4	Confident	89.2	Confident	82 Å²	82	56.5 Å²	56.5	85%	0.845	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	75	1.1	179.6	0	0	0	0	0	115.1	C135	C135-G137 PolarHBondContact O-N 3.12Å
138	C	90.3	Very high	88.9	Confident	26 Å²	26	59.5 Å²	59.5	18%	0.176	35%	0.348	C	S	.	.			trans	-76.9	140.4	177.1	-64.6	0	0	0	0	112	C135 F136 Y140 T146	C135-C138 HydrophobicContact CB-CB 4.18Å; C135-C138 WeakPolarHBondContact CB-SG 3.22Å; C135-C138 WeakPolarHBondContact O-CB 3.21Å; C135-C138 PolarHBondContact O-N 3.45Å; C135-C138 WeakPolarHBondContact SG-CB 3.27Å; C135-C138 CovalentContact SG-SG 2.02Å; C135-C138 PolarHBondContact SG-SG 3.2Å; F136-C138 PolarHBondContact O-N 3.41Å; C138-Y140 HydrophobicContact CB-CE2 3.76Å; C138-T146 WeakPolarHBondContact CA-OG1 3.39Å; C138-T146 HydrophobicContact CB-CG2 4.47Å
139	T	87.3	Confident	88.7	Confident	67 Å²	67	67.4 Å²	67.4	41%	0.411	38%	0.378	S	S	.	.			trans	-103.8	136	177.9	51.3	0	0	0	0	110.6	R144 S145 T146	T139-R144 PolarHBondContact OG1-O 3.43Å; T139-S145 WeakPolarHBondContact O-CA 3.29Å; T139-T146 PolarHBondContact N-OG1 3.03Å; T139-T146 PolarHBondContact O-N 2.88Å; T139-T146 VanDerWaalsContact O-N 3.13Å; T139-T146 PolarHBondContact OG1-OG1 2.91Å
140	Y	84.8	Confident	88.7	Confident	52 Å²	52	69.8 Å²	69.8	20%	0.204	39%	0.392	C	S	.	.			trans	-127.1	123.9	-178.8	-57.9	-89	0	0	0	109.8	L69 R134 C135 C138 T142 Q151	L69-Y140 HydrophobicContact CD2-CE1 4.21Å; R134-Y140 HydrophobicContact CB-CE2 3.89Å; R134-Y140 HydrophobicContact CG-CE2 3.98Å; C135-Y140 PolarHBondContact N-OH 3.47Å; C135-Y140 PolarHBondContact SG-OH 2.99Å; C138-Y140 HydrophobicContact CB-CE2 3.76Å; Y140-T142 VanDerWaalsContact C-N 3.25Å; Y140-T142 PolarHBondContact O-N 3.08Å; Y140-Q151 PolarHBondContact OH-OE1 2.68Å; Y140-Q151 VanDerWaalsContact OH-OE1 3.1Å
141	G	72.9	Confident	88.7	Confident	74 Å²	74	67.5 Å²	67.5	76%	0.763	38%	0.382	S	S	*	.	S	Bend	trans	75.1	-25.9	163.5	0	0	0	0	0	118.2	S145	G141-S145 PolarHBondContact N-OG 3.43Å
142	T	68.3	Low	88.7	Confident	140 Å²	140	68.8 Å²	68.8	86%	0.859	39%	0.389	S	S	*	.	S	Bend	trans	-95.5	5.9	-174.6	56.4	0	0	0	0	114.9	Y140	Y140-T142 VanDerWaalsContact C-N 3.25Å; Y140-T142 PolarHBondContact O-N 3.08Å
143	G	74.9	Confident	88.6	Confident	55 Å²	55	74 Å²	74	57%	0.567	42%	0.415	S	S	*	.	S	Bend	trans	178	-147.8	-178.7	0	0	0	0	0	112.4	S145	G143-S145 PolarHBondContact O-N 3.38Å
144	R	81.2	Confident	88.7	Confident	224 Å²	224	74.8 Å²	74.8	85%	0.845	42%	0.417	S	S	*	.	S	Bend	trans	-62.4	101	170.1	-172.5	177	-175.2	167.5	1.4	108.3	T139	T139-R144 PolarHBondContact OG1-O 3.43Å
145	S	85.8	Confident	88.8	Confident	60 Å²	60	70 Å²	70	42%	0.42	40%	0.399	S	S	.	.	P	Polyproline II helix	trans	-65.4	143.1	177.6	-63.4	0	0	0	0	109.3	T139 G141 G143	T139-S145 WeakPolarHBondContact O-CA 3.29Å; G141-S145 PolarHBondContact N-OG 3.43Å; G143-S145 PolarHBondContact O-N 3.38Å
146	T	91.9	Very high	89.1	Confident	26 Å²	26	70.8 Å²	70.8	16%	0.16	41%	0.406	C	S	.	.	P	Polyproline II helix	trans	-59.2	124.8	178.9	-56.7	0	0	0	0	109.7	C138 T139 V150 Q151	C138-T146 WeakPolarHBondContact CA-OG1 3.39Å; C138-T146 HydrophobicContact CB-CG2 4.47Å; T139-T146 PolarHBondContact N-OG1 3.03Å; T139-T146 PolarHBondContact O-N 2.88Å; T139-T146 VanDerWaalsContact O-N 3.13Å; T139-T146 PolarHBondContact OG1-OG1 2.91Å; T146-V150 HydrophobicContact CG2-CB 3.9Å; T146-V150 HydrophobicContact CG2-CG1 3.87Å; T146-Q151 HydrophobicContact CG2-CG 3.98Å; T146-Q151 PolarHBondContact O-NE2 2.93Å
147	P	92.5	Very high	89.4	Confident	51 Å²	51	67.9 Å²	67.9	33%	0.331	40%	0.4	S	S	.	.	P	Polyproline II helix	trans	-56.8	143.9	-178.5	-24.1	32.7	0	0	0	112.4	W149 V150 Q151	P147-W149 VanDerWaalsContact C-N 3.28Å; P147-W149 HydrophobicContact CB-CG 4.4Å; P147-W149 PolarHBondContact O-N 3.11Å; P147-V150 HydrophobicContact CB-CG2 4.21Å; P147-V150 HydrophobicContact CG-CG2 4.31Å; P147-V150 WeakPolarHBondContact O-CB 3.4Å; P147-V150 PolarHBondContact O-N 3.02Å; P147-Q151 PolarHBondContact O-N 2.73Å
148	E	92.8	Very high	90	Very high	64 Å²	64	66.1 Å²	66.1	30%	0.299	37%	0.369	S	S	.	.	H	α-helix	trans	-54.2	-42.7	-178.3	-63.7	-177.8	173.8	0	0	112.5	S72 A75 V150 Q151 L152	S72-E148 WeakPolarHBondContact CB-OE2 3.27Å; S72-E148 PolarHBondContact N-OE1 3.34Å; S72-E148 PolarHBondContact OG-OE2 3.06Å; A75-E148 HydrophobicContact CB-CB 4.49Å; A75-E148 WeakPolarHBondContact CB-OE2 3.44Å; E148-V150 PolarHBondContact O-N 3.45Å; E148-Q151 CarbonylContact O-C 3.51Å; E148-Q151 WeakPolarHBondContact O-CA 3.39Å; E148-Q151 WeakPolarHBondContact O-CB 3.38Å; E148-Q151 PolarHBondContact O-N 2.75Å; E148-L152 WeakPolarHBondContact O-CG 3.49Å; E148-L152 PolarHBondContact O-N 2.92Å
149	W	94.3	Very high	90.3	Very high	166 Å²	166	64.9 Å²	64.9	63%	0.629	36%	0.36	S	S	*	.	H	α-helix	trans	-61.5	-31.1	-179.4	70.8	-97	0	0	0	113.3	P147 L152 I153	P147-W149 VanDerWaalsContact C-N 3.28Å; P147-W149 HydrophobicContact CB-CG 4.4Å; P147-W149 PolarHBondContact O-N 3.11Å; W149-L152 PolarHBondContact O-N 3.48Å; W149-I153 HydrophobicContact CE3-CD1 3.61Å; W149-I153 HydrophobicContact CZ3-CD1 3.69Å; W149-I153 WeakPolarHBondContact O-CG1 3.46Å; W149-I153 PolarHBondContact O-N 3.09Å; W149-I153 VanDerWaalsContact O-N 3.11Å
150	V	95.3	Very high	90.8	Very high	52 Å²	52	64.8 Å²	64.8	32%	0.315	36%	0.359	S	S	.	.	H	α-helix	trans	-69.4	-43.6	174.5	178.6	0	0	0	0	109.6	T146 P147 E148 L152 I153 Y154	T146-V150 HydrophobicContact CG2-CB 3.9Å; T146-V150 HydrophobicContact CG2-CG1 3.87Å; P147-V150 HydrophobicContact CB-CG2 4.21Å; P147-V150 HydrophobicContact CG-CG2 4.31Å; P147-V150 WeakPolarHBondContact O-CB 3.4Å; P147-V150 PolarHBondContact O-N 3.02Å; E148-V150 PolarHBondContact O-N 3.45Å; V150-L152 VanDerWaalsContact C-N 3.33Å; V150-L152 PolarHBondContact O-N 3.01Å; V150-I153 PolarHBondContact O-N 3.19Å; V150-Y154 PolarHBondContact O-N 3.09Å; V150-Y154 VanDerWaalsContact O-N 3.09Å
151	Q	95.9	Very high	91.5	Very high	9 Å²	9	65.4 Å²	65.4	4%	0.042	37%	0.366	C	S	.	.	H	α-helix	trans	-65.2	-38	176.6	-54	-169	53.1	0	0	111.1	F71 C135 Y140 T146 P147 E148 I153 Y154 Y155	F71-Q151 HydrophobicContact CE1-CB 3.96Å; F71-Q151 HydrophobicContact CE1-CG 4.4Å; F71-Q151 HydrophobicContact CZ-CB 3.48Å; F71-Q151 VanDerWaalsContact CZ-CB 3.48Å; F71-Q151 HydrophobicContact CZ-CG 4.39Å; C135-Q151 VanDerWaalsContact SG-CG 3.57Å; C135-Q151 PolarHBondContact SG-OE1 3.21Å; Y140-Q151 PolarHBondContact OH-OE1 2.68Å; Y140-Q151 VanDerWaalsContact OH-OE1 3.1Å; T146-Q151 HydrophobicContact CG2-CG 3.98Å; T146-Q151 PolarHBondContact O-NE2 2.93Å; P147-Q151 PolarHBondContact O-N 2.73Å; E148-Q151 CarbonylContact O-C 3.51Å; E148-Q151 WeakPolarHBondContact O-CA 3.39Å; E148-Q151 WeakPolarHBondContact O-CB 3.38Å; E148-Q151 PolarHBondContact O-N 2.75Å; Q151-I153 PolarHBondContact O-N 3.41Å; Q151-Y154 WeakPolarHBondContact O-CB 3.3Å; Q151-Y154 PolarHBondContact O-N 3.01Å; Q151-Y154 VanDerWaalsContact O-N 3.12Å; Q151-Y155 HydrophobicContact CB-CD2 4.37Å; Q151-Y155 HydrophobicContact CB-CE2 4.12Å; Q151-Y155 WeakPolarHBondContact O-CD2 3.29Å; Q151-Y155 PolarHBondContact O-N 3.31Å
152	L	96.2	Very high	92.7	Very high	28 Å²	28	61.9 Å²	61.9	15%	0.147	33%	0.329	C	S	.	.	H	α-helix	trans	-58.5	-46.2	173.6	-72.1	176.1	0	0	0	111.9	F71 A75 H78 I79 E148 W149 V150 Y154 Y155 A156	F71-L152 HydrophobicContact CD2-CD2 4.26Å; F71-L152 HydrophobicContact CE2-CD2 3.7Å; F71-L152 HydrophobicContact CE2-CG 4.1Å; A75-L152 HydrophobicContact CB-CD1 4.1Å; A75-L152 HydrophobicContact CB-CD2 4.4Å; A75-L152 WeakPolarHBondContact O-CD2 2.9Å; H78-L152 HydrophobicContact CB-CD2 4.49Å; I79-L152 HydrophobicContact CD1-CD2 3.48Å; I79-L152 VanDerWaalsContact CD1-CD2 3.48Å; I79-L152 HydrophobicContact CG1-CD2 3.44Å; I79-L152 VanDerWaalsContact CG1-CD2 3.44Å; E148-L152 WeakPolarHBondContact O-CG 3.49Å; E148-L152 PolarHBondContact O-N 2.92Å; W149-L152 PolarHBondContact O-N 3.48Å; V150-L152 VanDerWaalsContact C-N 3.33Å; V150-L152 PolarHBondContact O-N 3.01Å; L152-Y154 PolarHBondContact O-N 3.21Å; L152-Y155 PolarHBondContact O-N 3.5Å; L152-A156 VanDerWaalsContact O-CB 3.25Å; L152-A156 WeakPolarHBondContact O-CB 3.39Å; L152-A156 PolarHBondContact O-N 2.76Å
153	I	96.3	Very high	94.1	Very high	110 Å²	110	55.4 Å²	55.4	56%	0.564	29%	0.29	S	S	*	.	H	α-helix	trans	-61.2	-35.8	175.7	-69.4	170.5	0	0	0	111.1	W149 V150 Q151 P157	W149-I153 HydrophobicContact CE3-CD1 3.61Å; W149-I153 HydrophobicContact CZ3-CD1 3.69Å; W149-I153 WeakPolarHBondContact O-CG1 3.46Å; W149-I153 PolarHBondContact O-N 3.09Å; W149-I153 VanDerWaalsContact O-N 3.11Å; V150-I153 PolarHBondContact O-N 3.19Å; Q151-I153 PolarHBondContact O-N 3.41Å; I153-P157 WeakPolarHBondContact O-CD 3.4Å
154	Y	96.8	Very high	95.1	Very high	50 Å²	50	56.1 Å²	56.1	20%	0.196	28%	0.28	C	S	.	.	H	α-helix	trans	-67.3	-47.1	175.7	172.8	-86.6	0	0	0	112.6	C135 F136 V150 Q151 L152 F158	C135-Y154 HydrophobicContact CB-CD1 3.29Å; C135-Y154 HydrophobicContact CB-CD2 4.13Å; C135-Y154 HydrophobicContact CB-CE1 3.42Å; C135-Y154 VanDerWaalsContact CB-CE1 3.42Å; C135-Y154 HydrophobicContact CB-CE2 4.24Å; C135-Y154 HydrophobicContact CB-CG 3.67Å; F136-Y154 HydrophobicContact CB-CE2 4.38Å; F136-Y154 HydrophobicContact CD2-CE2 4.1Å; F136-Y154 AromaticContact CD2-CZ 3.98Å; F136-Y154 WeakPolarHBondContact CD2-OH 3.5Å; F136-Y154 WeakPolarHBondContact CE2-OH 3.35Å; V150-Y154 PolarHBondContact O-N 3.09Å; V150-Y154 VanDerWaalsContact O-N 3.09Å; Q151-Y154 WeakPolarHBondContact O-CB 3.3Å; Q151-Y154 PolarHBondContact O-N 3.01Å; Q151-Y154 VanDerWaalsContact O-N 3.12Å; L152-Y154 PolarHBondContact O-N 3.21Å; Y154-F158 HydrophobicContact CD1-CE2 4.27Å; Y154-F158 HydrophobicContact CE1-CD2 4.25Å; Y154-F158 AromaticContact CE1-CE2 3.78Å; Y154-F158 HydrophobicContact CE1-CE2 3.78Å; Y154-F158 HydrophobicContact CE2-CE2 4.08Å; Y154-F158 AromaticContact CZ-CE2 3.67Å; Y154-F158 VanDerWaalsContact O-CD2 3.26Å; Y154-F158 WeakPolarHBondContact O-CD2 3.37Å; Y154-F158 WeakPolarHBondContact O-CE2 3.37Å
155	Y	97.8	Very high	95.8	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-78.2	-28.7	-176.3	-67.5	-67.2	0	0	0	113.6	F65 L69 F71 M133 C135 Q151 L152 F158 V159	F65-Y155 AromaticContact CE1-CD2 3.52Å; F65-Y155 HydrophobicContact CE1-CD2 3.52Å; F65-Y155 AromaticContact CE1-CE2 3.82Å; F65-Y155 HydrophobicContact CE1-CE2 3.82Å; F65-Y155 AromaticContact CE1-CG 3.94Å; F65-Y155 HydrophobicContact CE1-CG 3.94Å; F65-Y155 HydrophobicContact CZ-CD1 4.04Å; F65-Y155 AromaticContact CZ-CD2 3.83Å; F65-Y155 HydrophobicContact CZ-CD2 3.83Å; F65-Y155 HydrophobicContact CZ-CE1 4.37Å; F65-Y155 HydrophobicContact CZ-CE2 4.17Å; F65-Y155 AromaticContact CZ-CG 3.77Å; F65-Y155 HydrophobicContact CZ-CG 3.77Å; L69-Y155 HydrophobicContact CD1-CE2 3.75Å; L69-Y155 VanDerWaalsContact CD1-OH 3.28Å; L69-Y155 WeakPolarHBondContact CD1-OH 3.42Å; F71-Y155 HydrophobicContact CZ-CD2 4.28Å; F71-Y155 HydrophobicContact CZ-CE2 4.13Å; M133-Y155 WeakPolarHBondContact O-CE1 3.45Å; M133-Y155 PolarHBondContact O-OH 3.14Å; C135-Y155 HydrophobicContact CB-CE2 4.3Å; C135-Y155 PolarHBondContact N-OH 3.23Å; Q151-Y155 HydrophobicContact CB-CD2 4.37Å; Q151-Y155 HydrophobicContact CB-CE2 4.12Å; Q151-Y155 WeakPolarHBondContact O-CD2 3.29Å; Q151-Y155 PolarHBondContact O-N 3.31Å; L152-Y155 PolarHBondContact O-N 3.5Å; Y155-F158 PolarHBondContact O-N 3.03Å; Y155-F158 VanDerWaalsContact O-N 3.12Å; Y155-V159 WeakPolarHBondContact O-CG2 3.49Å; Y155-V159 PolarHBondContact O-N 2.68Å
156	A	97.9	Very high	96.3	Very high	21 Å²	21	43.8 Å²	43.8	17%	0.174	22%	0.224	C	C	.	.	H	α-helix	trans	-55.4	-47.6	-174.2	0	0	0	0	0	113.8	I82 L152 F158 V159 V160	I82-A156 HydrophobicContact CD1-CB 4.07Å; L152-A156 VanDerWaalsContact O-CB 3.25Å; L152-A156 WeakPolarHBondContact O-CB 3.39Å; L152-A156 PolarHBondContact O-N 2.76Å; A156-F158 VanDerWaalsContact C-N 3.33Å; A156-F158 PolarHBondContact O-N 3.45Å; A156-V159 PolarHBondContact O-N 2.93Å; A156-V160 WeakPolarHBondContact O-CG2 3.29Å; A156-V160 PolarHBondContact O-N 3.27Å
157	P	97.9	Very high	96.4	Very high	69 Å²	69	42.5 Å²	42.5	45%	0.448	22%	0.216	S	C	.	.	H	α-helix	trans	-58	-41.8	175.8	-25.6	34.6	0	0	0	113.4	I153 V159 V160 I161	I153-P157 WeakPolarHBondContact O-CD 3.4Å; P157-V159 VanDerWaalsContact C-N 3.33Å; P157-V159 PolarHBondContact O-N 2.78Å; P157-V160 PolarHBondContact O-N 3.47Å; P157-I161 WeakPolarHBondContact O-CB 3.34Å; P157-I161 WeakPolarHBondContact O-CD1 3.45Å; P157-I161 VanDerWaalsContact O-CG1 3.23Å; P157-I161 WeakPolarHBondContact O-CG1 3.49Å; P157-I161 PolarHBondContact O-N 3.33Å
158	F	98.1	Very high	96.5	Very high	44 Å²	44	40.3 Å²	40.3	19%	0.193	20%	0.202	C	C	.	.	H	α-helix	trans	-63.2	-41.3	177.2	-64	-68	0	0	0	111.4	S127 F130 L131 Y154 Y155 A156 I161 F162	S127-F158 WeakPolarHBondContact CB-O 3.28Å; F130-F158 HydrophobicContact CB-CD1 3.97Å; F130-F158 HydrophobicContact CB-CD2 4.4Å; F130-F158 HydrophobicContact CB-CE1 4.01Å; F130-F158 HydrophobicContact CB-CE2 4.45Å; F130-F158 HydrophobicContact CB-CG 4.16Å; F130-F158 HydrophobicContact CB-CZ 4.25Å; F130-F158 HydrophobicContact CD2-CD1 4.14Å; F130-F158 AromaticContact CD2-CE1 3.87Å; F130-F158 HydrophobicContact CD2-CE1 3.87Å; F130-F158 HydrophobicContact CG-CD1 4.29Å; F130-F158 AromaticContact CG-CE1 3.95Å; F130-F158 HydrophobicContact CG-CE1 3.95Å; F130-F158 HydrophobicContact CG-CZ 4.32Å; L131-F158 HydrophobicContact CD2-CB 3.67Å; L131-F158 HydrophobicContact CG-CB 4.46Å; Y154-F158 HydrophobicContact CD1-CE2 4.27Å; Y154-F158 HydrophobicContact CE1-CD2 4.25Å; Y154-F158 AromaticContact CE1-CE2 3.78Å; Y154-F158 HydrophobicContact CE1-CE2 3.78Å; Y154-F158 HydrophobicContact CE2-CE2 4.08Å; Y154-F158 AromaticContact CZ-CE2 3.67Å; Y154-F158 VanDerWaalsContact O-CD2 3.26Å; Y154-F158 WeakPolarHBondContact O-CD2 3.37Å; Y154-F158 WeakPolarHBondContact O-CE2 3.37Å; Y155-F158 PolarHBondContact O-N 3.03Å; Y155-F158 VanDerWaalsContact O-N 3.12Å; A156-F158 VanDerWaalsContact C-N 3.33Å; A156-F158 PolarHBondContact O-N 3.45Å; F158-I161 PolarHBondContact O-N 2.95Å; F158-F162 WeakPolarHBondContact O-CB 3.3Å; F158-F162 PolarHBondContact O-N 3.3Å
159	V	98.1	Very high	96.7	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-61.7	-49.7	175.4	174.1	0	0	0	0	110.6	W57 I79 I82 L131 Y155 A156 P157 I161 F162 Q163	W57-V159 HydrophobicContact CH2-CG1 3.77Å; W57-V159 HydrophobicContact CH2-CG2 4.48Å; W57-V159 HydrophobicContact CZ3-CG1 4.25Å; W57-V159 HydrophobicContact CZ3-CG2 4.4Å; I79-V159 HydrophobicContact CG2-CG2 4.11Å; I82-V159 HydrophobicContact CB-CG1 4.5Å; I82-V159 HydrophobicContact CG2-CB 4.42Å; I82-V159 HydrophobicContact CG2-CG1 4.02Å; L131-V159 HydrophobicContact CD2-CB 4.47Å; L131-V159 HydrophobicContact CD2-CG2 3.53Å; Y155-V159 WeakPolarHBondContact O-CG2 3.49Å; Y155-V159 PolarHBondContact O-N 2.68Å; A156-V159 PolarHBondContact O-N 2.93Å; P157-V159 VanDerWaalsContact C-N 3.33Å; P157-V159 PolarHBondContact O-N 2.78Å; V159-I161 VanDerWaalsContact C-N 3.35Å; V159-I161 PolarHBondContact O-N 2.81Å; V159-F162 PolarHBondContact O-N 2.82Å; V159-Q163 HydrophobicContact CG1-CG 4.35Å; V159-Q163 VanDerWaalsContact O-CG 3.29Å; V159-Q163 WeakPolarHBondContact O-CG 3.39Å; V159-Q163 PolarHBondContact O-N 3.3Å
160	V	98.3	Very high	96.6	Very high	65 Å²	65	31.7 Å²	31.7	39%	0.394	17%	0.169	S	C	.	.	H	α-helix	trans	-59.3	-46.2	-179.7	177.4	0	0	0	0	111.2	I82 S86 A156 P157 Q163 L164	I82-V160 HydrophobicContact CG2-CG2 3.96Å; S86-V160 WeakPolarHBondContact OG-CG2 3.34Å; A156-V160 WeakPolarHBondContact O-CG2 3.29Å; A156-V160 PolarHBondContact O-N 3.27Å; P157-V160 PolarHBondContact O-N 3.47Å; V160-Q163 PolarHBondContact O-N 2.95Å; V160-L164 PolarHBondContact O-N 3.48Å
161	I	98.2	Very high	96.4	Very high	65 Å²	65	30.7 Å²	30.7	33%	0.333	16%	0.161	S	C	.	.	H	α-helix	trans	-63.5	-44.2	178.6	-68.4	166.9	0	0	0	110.8	L123 P157 F158 V159 Q163 L164 G165	L123-I161 HydrophobicContact CB-CG2 4.04Å; L123-I161 HydrophobicContact CD2-CG2 4.08Å; P157-I161 WeakPolarHBondContact O-CB 3.34Å; P157-I161 WeakPolarHBondContact O-CD1 3.45Å; P157-I161 VanDerWaalsContact O-CG1 3.23Å; P157-I161 WeakPolarHBondContact O-CG1 3.49Å; P157-I161 PolarHBondContact O-N 3.33Å; F158-I161 PolarHBondContact O-N 2.95Å; V159-I161 VanDerWaalsContact C-N 3.35Å; V159-I161 PolarHBondContact O-N 2.81Å; I161-Q163 PolarHBondContact O-N 3.36Å; I161-L164 PolarHBondContact O-N 2.86Å; I161-G165 PolarHBondContact O-N 3.46Å
162	F	98.1	Very high	96.1	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-59	-46.1	177.1	168.7	-114.4	0	0	0	111.4	C53 W57 V124 S127 F128 L131 F158 V159 G165 W166	C53-F162 HydrophobicContact CB-CE2 3.82Å; C53-F162 HydrophobicContact CB-CZ 3.86Å; W57-F162 HydrophobicContact CD2-CE1 4.11Å; W57-F162 HydrophobicContact CE3-CD1 4.07Å; W57-F162 AromaticContact CE3-CE1 3.7Å; W57-F162 HydrophobicContact CE3-CE1 3.7Å; W57-F162 HydrophobicContact CZ3-CD1 4.19Å; W57-F162 HydrophobicContact CZ3-CE1 4.27Å; V124-F162 HydrophobicContact CG1-CD2 4.03Å; V124-F162 HydrophobicContact CG1-CE2 4Å; V124-F162 HydrophobicContact CG2-CD2 4.23Å; V124-F162 HydrophobicContact CG2-CE2 4.44Å; S127-F162 VanDerWaalsContact OG-CA 3.27Å; S127-F162 WeakPolarHBondContact OG-CA 3.48Å; S127-F162 WeakPolarHBondContact OG-CB 3.41Å; S127-F162 PolarHBondContact OG-N 3.17Å; F128-F162 HydrophobicContact CB-CD2 3.95Å; F128-F162 HydrophobicContact CB-CE2 4.23Å; F128-F162 AromaticContact CD2-CD2 3.75Å; F128-F162 HydrophobicContact CD2-CD2 3.75Å; F128-F162 HydrophobicContact CD2-CE1 4.36Å; F128-F162 AromaticContact CD2-CE2 3.39Å; F128-F162 HydrophobicContact CD2-CE2 3.39Å; F128-F162 HydrophobicContact CD2-CG 4.38Å; F128-F162 AromaticContact CD2-CZ 3.73Å; F128-F162 HydrophobicContact CD2-CZ 3.73Å; F128-F162 HydrophobicContact CE2-CE2 4.13Å; F128-F162 HydrophobicContact CE2-CZ 4.06Å; F128-F162 HydrophobicContact CG-CD2 4.29Å; F128-F162 HydrophobicContact CG-CE2 4.13Å; L131-F162 HydrophobicContact CD1-CB 4.17Å; L131-F162 HydrophobicContact CD1-CD1 3.94Å; L131-F162 HydrophobicContact CD1-CG 4.05Å; F158-F162 WeakPolarHBondContact O-CB 3.3Å; F158-F162 PolarHBondContact O-N 3.3Å; V159-F162 PolarHBondContact O-N 2.82Å; F162-G165 PolarHBondContact O-N 3.1Å; F162-W166 HydrophobicContact CE2-CE3 4.3Å; F162-W166 AromaticContact CZ-CE3 3.79Å; F162-W166 HydrophobicContact CZ-CE3 3.79Å; F162-W166 HydrophobicContact CZ-CZ3 4.44Å; F162-W166 VanDerWaalsContact O-CB 3.3Å; F162-W166 WeakPolarHBondContact O-CB 3.37Å; F162-W166 PolarHBondContact O-N 3.43Å
163	Q	97.1	Very high	95.9	Very high	5 Å²	5	29 Å²	29	2%	0.023	15%	0.153	C	C	.	.	H	α-helix	trans	-69	-36.2	-179.7	-63.8	-57.9	142.9	0	0	113	G83 D87 V159 V160 I161 G165 W166 A167	G83-Q163 VanDerWaalsContact O-CG 3.28Å; G83-Q163 WeakPolarHBondContact O-CG 3.38Å; D87-Q163 HydrophobicContact CB-CB 4.18Å; D87-Q163 HydrophobicContact CB-CG 4.39Å; D87-Q163 VanDerWaalsContact CB-NE2 3.33Å; V159-Q163 HydrophobicContact CG1-CG 4.35Å; V159-Q163 VanDerWaalsContact O-CG 3.29Å; V159-Q163 WeakPolarHBondContact O-CG 3.39Å; V159-Q163 PolarHBondContact O-N 3.3Å; V160-Q163 PolarHBondContact O-N 2.95Å; I161-Q163 PolarHBondContact O-N 3.36Å; Q163-G165 VanDerWaalsContact C-N 3.34Å; Q163-W166 WeakPolarHBondContact O-CB 3.2Å; Q163-W166 PolarHBondContact O-N 2.92Å; Q163-A167 WeakPolarHBondContact O-CB 3.45Å; Q163-A167 PolarHBondContact O-N 3.06Å
164	L	96.4	Very high	95.6	Very high	69 Å²	69	26.9 Å²	26.9	36%	0.361	14%	0.142	S	C	.	.	H	α-helix	trans	-63.6	-43.1	171.9	179.9	62.1	0	0	0	111.3	A90 V94 L123 V160 I161 A167 S168	A90-L164 HydrophobicContact CB-CD1 3.92Å; V94-L164 HydrophobicContact CG2-CD1 3.9Å; L123-L164 HydrophobicContact CD1-CB 4.34Å; L123-L164 HydrophobicContact CD1-CD2 3.88Å; L123-L164 HydrophobicContact CD1-CG 3.84Å; V160-L164 PolarHBondContact O-N 3.48Å; I161-L164 PolarHBondContact O-N 2.86Å; L164-A167 PolarHBondContact O-N 3.03Å; L164-S168 WeakPolarHBondContact O-CB 3.48Å; L164-S168 PolarHBondContact O-N 2.97Å; L164-S168 PolarHBondContact O-OG 3.02Å
165	G	97.3	Very high	95.1	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-62.1	-47.1	175.6	0	0	0	0	0	112.3	G120 I161 F162 Q163 A167 S168 V169	G120-G165 WeakPolarHBondContact CA-O 3.07Å; G120-G165 WeakPolarHBondContact O-CA 3.45Å; I161-G165 PolarHBondContact O-N 3.46Å; F162-G165 PolarHBondContact O-N 3.1Å; Q163-G165 VanDerWaalsContact C-N 3.34Å; G165-A167 PolarHBondContact O-N 3.4Å; G165-S168 WeakPolarHBondContact O-CB 3.28Å; G165-S168 PolarHBondContact O-N 3.1Å; G165-V169 PolarHBondContact O-N 3.45Å
166	W	96	Very high	94.6	Very high	25 Å²	25	25.5 Å²	25.5	10%	0.095	14%	0.142	C	C	.	.	H	α-helix	trans	-52.7	-54.1	174.7	172.9	-76.2	0	0	0	111.3	N50 C53 A54 F162 Q163 S168 V169 Q170	N50-W166 HydrophobicContact CB-CD2 4.44Å; N50-W166 HydrophobicContact CB-CE3 4.07Å; N50-W166 HydrophobicContact CB-CH2 4Å; N50-W166 HydrophobicContact CB-CZ2 4.43Å; N50-W166 HydrophobicContact CB-CZ3 3.88Å; N50-W166 PolarHBondContact ND2-O 2.97Å; N50-W166 WeakPolarHBondContact O-CH2 3.5Å; N50-W166 WeakPolarHBondContact O-CZ3 3.48Å; C53-W166 HydrophobicContact CB-CZ3 4.44Å; A54-W166 HydrophobicContact CB-CH2 3.24Å; A54-W166 HydrophobicContact CB-CZ2 4.41Å; A54-W166 HydrophobicContact CB-CZ3 3.56Å; F162-W166 HydrophobicContact CE2-CE3 4.3Å; F162-W166 AromaticContact CZ-CE3 3.79Å; F162-W166 HydrophobicContact CZ-CE3 3.79Å; F162-W166 HydrophobicContact CZ-CZ3 4.44Å; F162-W166 VanDerWaalsContact O-CB 3.3Å; F162-W166 WeakPolarHBondContact O-CB 3.37Å; F162-W166 PolarHBondContact O-N 3.43Å; Q163-W166 WeakPolarHBondContact O-CB 3.2Å; Q163-W166 PolarHBondContact O-N 2.92Å; W166-S168 VanDerWaalsContact C-N 3.32Å; W166-S168 PolarHBondContact O-N 2.87Å; W166-V169 PolarHBondContact O-N 3.32Å; W166-Q170 WeakPolarHBondContact O-CB 3.19Å; W166-Q170 PolarHBondContact O-N 3.44Å
167	A	94.2	Very high	94	Very high	0 Å²	0	25 Å²	25	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-61.5	-41.8	-178.5	0	0	0	0	0	111.3	A90 V94 Q163 L164 G165 Q170 I171	A90-A167 HydrophobicContact CB-CB 3.88Å; V94-A167 HydrophobicContact CG2-CB 4.4Å; Q163-A167 WeakPolarHBondContact O-CB 3.45Å; Q163-A167 PolarHBondContact O-N 3.06Å; L164-A167 PolarHBondContact O-N 3.03Å; G165-A167 PolarHBondContact O-N 3.4Å; A167-Q170 PolarHBondContact O-N 2.98Å; A167-I171 WeakPolarHBondContact O-CB 3.39Å; A167-I171 WeakPolarHBondContact O-CG1 3.44Å; A167-I171 PolarHBondContact O-N 3Å
168	S	94.4	Very high	93.2	Very high	5 Å²	5	24.5 Å²	24.5	4%	0.035	13%	0.133	C	C	.	.	H	α-helix	trans	-60	-48.8	177.4	-59.6	0	0	0	0	112.7	L164 G165 W166 G172	L164-S168 WeakPolarHBondContact O-CB 3.48Å; L164-S168 PolarHBondContact O-N 2.97Å; L164-S168 PolarHBondContact O-OG 3.02Å; G165-S168 WeakPolarHBondContact O-CB 3.28Å; G165-S168 PolarHBondContact O-N 3.1Å; W166-S168 VanDerWaalsContact C-N 3.32Å; W166-S168 PolarHBondContact O-N 2.87Å; S168-G172 PolarHBondContact O-N 3.44Å
169	V	96	Very high	92.4	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-61.6	-48.4	174.9	168.6	0	0	0	0	110.8	N50 G165 W166 I171 H173	N50-V169 HydrophobicContact CB-CG1 4.4Å; N50-V169 WeakPolarHBondContact OD1-CG1 3.45Å; G165-V169 PolarHBondContact O-N 3.45Å; W166-V169 PolarHBondContact O-N 3.32Å; V169-I171 PolarHBondContact O-N 3Å; V169-H173 WeakPolarHBondContact O-CB 3.34Å; V169-H173 PolarHBondContact O-N 3.13Å
170	Q	93.4	Very high	91.7	Very high	48 Å²	48	26.6 Å²	26.6	22%	0.224	14%	0.144	C	C	.	.	H	α-helix	trans	-61.8	-48.4	-175.2	-179.3	168.6	0.2	0	0	112.2	W166 A167 L174	W166-Q170 WeakPolarHBondContact O-CB 3.19Å; W166-Q170 PolarHBondContact O-N 3.44Å; A167-Q170 PolarHBondContact O-N 2.98Å; Q170-L174 HydrophobicContact CG-CD1 4.09Å; Q170-L174 WeakPolarHBondContact O-CB 3.49Å; Q170-L174 WeakPolarHBondContact O-CG 3.39Å; Q170-L174 PolarHBondContact O-N 3.42Å
171	I	89.3	Confident	90.9	Very high	31 Å²	31	23.5 Å²	23.5	16%	0.159	13%	0.125	C	C	.	.	H	α-helix	trans	-70.4	-47.5	-178.3	-67.6	176.2	0	0	0	110.4	T91 V94 A167 V169 H173 L174 A175	T91-I171 HydrophobicContact CG2-CD1 3.97Å; T91-I171 WeakPolarHBondContact O-CD1 3.27Å; V94-I171 HydrophobicContact CB-CD1 3.9Å; V94-I171 HydrophobicContact CG1-CB 3.9Å; V94-I171 HydrophobicContact CG1-CD1 3.66Å; V94-I171 HydrophobicContact CG1-CG1 4.29Å; V94-I171 HydrophobicContact CG1-CG2 4.18Å; A167-I171 WeakPolarHBondContact O-CB 3.39Å; A167-I171 WeakPolarHBondContact O-CG1 3.44Å; A167-I171 PolarHBondContact O-N 3Å; V169-I171 PolarHBondContact O-N 3Å; I171-H173 VanDerWaalsContact C-N 3.25Å; I171-H173 PolarHBondContact O-N 3.18Å; I171-L174 PolarHBondContact O-N 2.99Å; I171-A175 VanDerWaalsContact O-CB 3.27Å; I171-A175 WeakPolarHBondContact O-CB 3.35Å; I171-A175 PolarHBondContact O-N 2.97Å
172	G	89.9	Confident	89.9	Confident	1 Å²	1	25 Å²	25	1%	0.01	14%	0.139	C	C	.	.	H	α-helix	trans	-56.4	-41.6	177	0	0	0	0	0	112.1	S168 L176	S168-G172 PolarHBondContact O-N 3.44Å; G172-L176 PolarHBondContact O-N 3.47Å
173	H	92.8	Very high	89.1	Confident	0 Å²	0	31 Å²	31	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-68.4	-43.5	177.8	-173.4	-128.7	0	0	0	113.3	F43 H47 V169 I171 L176 R194 F248	F43-H173 AromaticContact CD2-NE2 3.65Å; F43-H173 AromaticContact CE1-CE1 3.82Å; F43-H173 AromaticContact CE1-NE2 3.67Å; F43-H173 AromaticContact CE2-CD2 3.55Å; F43-H173 AromaticContact CE2-CE1 4Å; F43-H173 AromaticContact CE2-NE2 3.26Å; F43-H173 VanDerWaalsContact CE2-NE2 3.26Å; F43-H173 WeakPolarHBondContact CE2-NE2 3.49Å; F43-H173 AromaticContact CG-NE2 3.99Å; F43-H173 AromaticContact CZ-CD2 3.85Å; F43-H173 AromaticContact CZ-CE1 3.51Å; F43-H173 AromaticContact CZ-NE2 3.24Å; F43-H173 WeakPolarHBondContact CZ-NE2 3.32Å; F43-H173 PolarHBondContact O-NE2 2.9Å; H47-H173 AromaticContact CG-ND1 3.89Å; H47-H173 AromaticContact ND1-ND1 4Å; V169-H173 WeakPolarHBondContact O-CB 3.34Å; V169-H173 PolarHBondContact O-N 3.13Å; I171-H173 VanDerWaalsContact C-N 3.25Å; I171-H173 PolarHBondContact O-N 3.18Å; H173-L176 WeakPolarHBondContact O-CB 3.3Å; H173-L176 PolarHBondContact O-N 3.48Å; H173-R194 PolarHBondContact ND1-NH1 2.87Å; H173-R194 VanDerWaalsContact ND1-NH1 3.16Å; H173-F248 AromaticContact CD2-CE2 3.87Å
174	L	89.9	Confident	88	Confident	66 Å²	66	39.4 Å²	39.4	35%	0.346	20%	0.199	S	C	.	.	H	α-helix	trans	-68.2	-40.3	178.5	-74.8	171.6	0	0	0	112.5	Q170 I171 L176 I177 P178 R194	Q170-L174 HydrophobicContact CG-CD1 4.09Å; Q170-L174 WeakPolarHBondContact O-CB 3.49Å; Q170-L174 WeakPolarHBondContact O-CG 3.39Å; Q170-L174 PolarHBondContact O-N 3.42Å; I171-L174 PolarHBondContact O-N 2.99Å; L174-L176 PolarHBondContact O-N 3.03Å; L174-I177 HydrophobicContact CD2-CD1 4.09Å; L174-I177 WeakPolarHBondContact O-CB 3.32Å; L174-I177 PolarHBondContact O-N 3.05Å; L174-P178 WeakPolarHBondContact O-CD 3.44Å; L174-R194 VanDerWaalsContact CD2-NH1 3.29Å; L174-R194 VanDerWaalsContact CG-NH1 3.33Å
175	A	85.6	Confident	87.1	Confident	21 Å²	21	41 Å²	41	17%	0.174	21%	0.208	C	C	.	.	H	α-helix	trans	-65.3	-21.9	179	0	0	0	0	0	112.8	R113 I171 P178	R113-A175 HydrophobicContact CG-CB 4.29Å; I171-A175 VanDerWaalsContact O-CB 3.27Å; I171-A175 WeakPolarHBondContact O-CB 3.35Å; I171-A175 PolarHBondContact O-N 2.97Å; A175-P178 VanDerWaalsContact O-CD 3.27Å; A175-P178 WeakPolarHBondContact O-CD 3.4Å; A175-P178 VanDerWaalsContact O-CG 3.32Å; A175-P178 WeakPolarHBondContact O-CG 3.34Å
176	L	87.7	Confident	86.3	Confident	1 Å²	1	41.6 Å²	41.6	1%	0.005	21%	0.211	C	C	.	.	H	α-helix	trans	-75.9	-25	178.3	-172.3	60.7	0	0	0	113.4	R113 G172 H173 L174 E179 L180 F248 I252 E254	R113-L176 HydrophobicContact CB-CB 4.45Å; R113-L176 HydrophobicContact CB-CD1 4.4Å; G172-L176 PolarHBondContact O-N 3.47Å; H173-L176 WeakPolarHBondContact O-CB 3.3Å; H173-L176 PolarHBondContact O-N 3.48Å; L174-L176 PolarHBondContact O-N 3.03Å; L176-E179 PolarHBondContact O-N 2.94Å; L176-L180 HydrophobicContact CD1-CD1 4.45Å; L176-L180 HydrophobicContact CD1-CD2 4.38Å; L176-L180 HydrophobicContact CD1-CG 4.04Å; L176-L180 HydrophobicContact CD2-CD1 4.15Å; L176-L180 HydrophobicContact CG-CD1 3.75Å; L176-L180 HydrophobicContact CG-CG 3.84Å; L176-L180 WeakPolarHBondContact O-CG 3.41Å; L176-L180 PolarHBondContact O-N 3.49Å; L176-F248 HydrophobicContact CD2-CE2 3.95Å; L176-F248 HydrophobicContact CD2-CZ 3.61Å; L176-I252 HydrophobicContact CD2-CG2 4.03Å; L176-E254 HydrophobicContact CD1-CG 4.27Å
177	I	86.4	Confident	85.6	Confident	9 Å²	9	44.3 Å²	44.3	5%	0.046	22%	0.221	C	C	.	.	H	α-helix	trans	-54.4	-53.7	178.8	-64.8	172.8	0	0	0	112.5	F43 L174 E179 L180 S181 R187 L190 N191	F43-I177 HydrophobicContact CE1-CD1 4.35Å; F43-I177 HydrophobicContact CE1-CG1 4.05Å; F43-I177 HydrophobicContact CE2-CG1 3.69Å; F43-I177 HydrophobicContact CZ-CD1 3.72Å; F43-I177 HydrophobicContact CZ-CG1 3.2Å; L174-I177 HydrophobicContact CD2-CD1 4.09Å; L174-I177 WeakPolarHBondContact O-CB 3.32Å; L174-I177 PolarHBondContact O-N 3.05Å; I177-E179 VanDerWaalsContact C-N 3.27Å; I177-E179 PolarHBondContact O-N 3.38Å; I177-L180 PolarHBondContact O-N 3.42Å; I177-S181 PolarHBondContact O-N 2.83Å; I177-R187 HydrophobicContact CG2-CB 3.8Å; I177-R187 HydrophobicContact CG2-CG 3.75Å; I177-L190 HydrophobicContact CG2-CD1 4.33Å; I177-N191 WeakPolarHBondContact CD1-OD1 3.39Å
178	P	81.1	Confident	84.8	Confident	60 Å²	60	47.2 Å²	47.2	39%	0.39	25%	0.245	S	C	.	.	H	α-helix	trans	-69.5	-23.5	-179.8	27.7	-37.1	0	0	0	114	L174 A175 R187	L174-P178 WeakPolarHBondContact O-CD 3.44Å; A175-P178 VanDerWaalsContact O-CD 3.27Å; A175-P178 WeakPolarHBondContact O-CD 3.4Å; A175-P178 VanDerWaalsContact O-CG 3.32Å; A175-P178 WeakPolarHBondContact O-CG 3.34Å; P178-R187 PolarHBondContact O-NH2 3.04Å; P178-R187 VanDerWaalsContact O-NH2 3.1Å
179	E	81	Confident	84.4	Confident	57 Å²	57	49.9 Å²	49.9	27%	0.266	26%	0.261	S	S	.	.	H	α-helix	trans	-78.9	-32.2	177.3	-66.6	179.6	-173.2	0	0	111.9	R112 R113 L176 I177	R112-E179 IonicContact NH2-OE1 2.82Å; R113-E179 WeakPolarHBondContact CG-OE1 3.24Å; R113-E179 VanDerWaalsContact CG-OE2 3.23Å; R113-E179 WeakPolarHBondContact CG-OE2 3.38Å; R113-E179 IonicContact CZ-OE1 3.69Å; R113-E179 IonicContact NE-OE1 3.7Å; R113-E179 PolarHBondContact NE-OE1 3.39Å; R113-E179 IonicContact NH2-OE1 3.72Å; L176-E179 PolarHBondContact O-N 2.94Å; I177-E179 VanDerWaalsContact C-N 3.27Å; I177-E179 PolarHBondContact O-N 3.38Å
180	L	82.9	Confident	84	Confident	30 Å²	30	49.9 Å²	49.9	16%	0.157	26%	0.261	C	S	.	.	H	α-helix	trans	-76.8	-30.4	178	-73.9	175.3	0	0	0	113.9	L35 F43 L176 I177 I252	L35-L180 HydrophobicContact CD1-CB 4.03Å; L35-L180 HydrophobicContact CD2-CB 4.35Å; L35-L180 HydrophobicContact CD2-CD2 4.39Å; F43-L180 HydrophobicContact CB-CD1 4.5Å; F43-L180 HydrophobicContact CD2-CD1 3.62Å; F43-L180 HydrophobicContact CE2-CD1 4.3Å; F43-L180 HydrophobicContact CG-CD1 4.33Å; L176-L180 HydrophobicContact CD1-CD1 4.45Å; L176-L180 HydrophobicContact CD1-CD2 4.38Å; L176-L180 HydrophobicContact CD1-CG 4.04Å; L176-L180 HydrophobicContact CD2-CD1 4.15Å; L176-L180 HydrophobicContact CG-CD1 3.75Å; L176-L180 HydrophobicContact CG-CG 3.84Å; L176-L180 WeakPolarHBondContact O-CG 3.41Å; L176-L180 PolarHBondContact O-N 3.49Å; I177-L180 PolarHBondContact O-N 3.42Å; L180-I252 HydrophobicContact CD1-CD1 4.32Å; L180-I252 HydrophobicContact CD1-CG2 4.45Å; L180-I252 HydrophobicContact CD2-CG2 3.97Å
181	S	81.4	Confident	83.6	Confident	1 Å²	1	50.9 Å²	50.9	1%	0.007	27%	0.268	C	S	.	.			trans	-148.4	133.4	179.5	-179.4	0	0	0	0	112.5	I177 Y183 E186 R187	I177-S181 PolarHBondContact O-N 2.83Å; S181-Y183 VanDerWaalsContact C-N 3.31Å; S181-Y183 PolarHBondContact OG-N 2.89Å; S181-Y183 VanDerWaalsContact OG-N 3.14Å; S181-E186 WeakPolarHBondContact CB-OE2 3.43Å; S181-E186 WeakPolarHBondContact OG-CB 3.47Å; S181-E186 PolarHBondContact OG-OE2 2.8Å; S181-R187 PolarHBondContact O-NE 3.3Å; S181-R187 PolarHBondContact O-NH2 2.97Å; S181-R187 VanDerWaalsContact O-NH2 3.1Å
182	P	77.5	Confident	83.4	Confident	95 Å²	95	51.2 Å²	51.2	62%	0.617	28%	0.279	S	S	*	.	S	Bend	trans	-77.6	-17.5	170.6	32.5	-33.9	0	0	0	112.7
183	Y	80.1	Confident	83.4	Confident	127 Å²	127	53 Å²	53	50%	0.498	29%	0.288	S	S	.	.			trans	-84.2	127.6	-170	-56.9	-71.4	0	0	0	112.5	S181 D185 E186 R187	S181-Y183 VanDerWaalsContact C-N 3.31Å; S181-Y183 PolarHBondContact OG-N 2.89Å; S181-Y183 VanDerWaalsContact OG-N 3.14Å; Y183-D185 PolarHBondContact O-N 3.46Å; Y183-E186 PolarHBondContact O-N 3.48Å; Y183-R187 WeakPolarHBondContact O-CG 3.29Å; Y183-R187 PolarHBondContact O-N 3.47Å
184	K	75.5	Confident	83.3	Confident	181 Å²	181	54.4 Å²	54.4	79%	0.787	29%	0.293	S	S	*	.	H	α-helix	trans	-58.5	-43.8	-178	-71.5	-176.1	179	178.9	0	113.3	E186 R187 A188	K184-E186 VanDerWaalsContact C-N 3.33Å; K184-E186 PolarHBondContact O-N 3.38Å; K184-R187 PolarHBondContact O-N 3.34Å; K184-A188 PolarHBondContact O-N 3.25Å
185	D	76.5	Confident	83.2	Confident	104 Å²	104	54.9 Å²	54.9	56%	0.556	29%	0.291	S	S	*	.	H	α-helix	trans	-68	-34.6	-178.8	-73.3	-36.2	0	0	0	112	Y183 A188 T189 R354	Y183-D185 PolarHBondContact O-N 3.46Å; D185-A188 PolarHBondContact O-N 3.34Å; D185-T189 PolarHBondContact O-N 3.45Å; D185-T189 PolarHBondContact O-OG1 2.96Å; D185-R354 IonicContact OD1-NH2 3.37Å; D185-R354 PolarHBondContact OD1-NH2 2.9Å; D185-R354 IonicContact OD2-NH2 2.72Å
186	E	80.4	Confident	83.3	Confident	12 Å²	12	55.8 Å²	55.8	6%	0.056	30%	0.299	C	S	.	.	H	α-helix	trans	-70.6	-40.8	174.6	-174.8	159.8	-128.9	0	0	111.6	L35 R40 S181 Y183 K184 A188 T189 L190	L35-E186 VanDerWaalsContact CB-OE1 3.28Å; L35-E186 WeakPolarHBondContact CB-OE1 3.44Å; L35-E186 HydrophobicContact CD1-CG 4.08Å; L35-E186 PolarHBondContact N-OE1 3.16Å; R40-E186 IonicContact CZ-OE1 3.96Å; R40-E186 IonicContact NE-OE1 3.21Å; R40-E186 PolarHBondContact NE-OE1 3Å; R40-E186 VanDerWaalsContact NE-OE1 3.12Å; R40-E186 IonicContact NH2-OE1 3.66Å; R40-E186 PolarHBondContact NH2-OE1 3.33Å; S181-E186 WeakPolarHBondContact CB-OE2 3.43Å; S181-E186 WeakPolarHBondContact OG-CB 3.47Å; S181-E186 PolarHBondContact OG-OE2 2.8Å; Y183-E186 PolarHBondContact O-N 3.48Å; K184-E186 VanDerWaalsContact C-N 3.33Å; K184-E186 PolarHBondContact O-N 3.38Å; E186-A188 VanDerWaalsContact C-N 3.29Å; E186-A188 PolarHBondContact O-N 3.29Å; E186-T189 WeakPolarHBondContact O-CA 3.27Å; E186-T189 VanDerWaalsContact O-CB 3.32Å; E186-T189 WeakPolarHBondContact O-CB 3.45Å; E186-T189 PolarHBondContact O-N 3.04Å; E186-T189 VanDerWaalsContact O-N 3.08Å; E186-L190 WeakPolarHBondContact O-CG 3.08Å; E186-L190 PolarHBondContact O-N 3.33Å
187	R	82	Confident	83.6	Confident	82 Å²	82	57.5 Å²	57.5	31%	0.309	31%	0.306	S	S	.	.	H	α-helix	trans	-59.8	-38.9	171.8	-66.1	176.5	-179.6	-175.8	-3.2	112.3	I177 P178 S181 Y183 K184 T189 L190 N191	I177-R187 HydrophobicContact CG2-CB 3.8Å; I177-R187 HydrophobicContact CG2-CG 3.75Å; P178-R187 PolarHBondContact O-NH2 3.04Å; P178-R187 VanDerWaalsContact O-NH2 3.1Å; S181-R187 PolarHBondContact O-NE 3.3Å; S181-R187 PolarHBondContact O-NH2 2.97Å; S181-R187 VanDerWaalsContact O-NH2 3.1Å; Y183-R187 WeakPolarHBondContact O-CG 3.29Å; Y183-R187 PolarHBondContact O-N 3.47Å; K184-R187 PolarHBondContact O-N 3.34Å; R187-T189 VanDerWaalsContact C-N 3.34Å; R187-L190 PolarHBondContact O-N 3.12Å; R187-N191 PolarHBondContact O-N 3.36Å; R187-N191 VanDerWaalsContact O-N 3.08Å; R187-N191 PolarHBondContact O-ND2 3.38Å
188	A	77.6	Confident	83.9	Confident	60 Å²	60	58.4 Å²	58.4	50%	0.496	31%	0.312	S	S	.	.	H	α-helix	trans	-64.2	-41.7	173.9	0	0	0	0	0	111.1	K184 D185 E186 N191 G192	K184-A188 PolarHBondContact O-N 3.25Å; D185-A188 PolarHBondContact O-N 3.34Å; E186-A188 VanDerWaalsContact C-N 3.29Å; E186-A188 PolarHBondContact O-N 3.29Å; A188-N191 PolarHBondContact O-N 3.33Å; A188-G192 PolarHBondContact O-N 3.42Å
189	T	84.8	Confident	84.3	Confident	61 Å²	61	55.8 Å²	55.8	37%	0.374	30%	0.295	S	S	.	.	H	α-helix	trans	-60.9	-46.1	175.2	-55.6	0	0	0	0	111.7	D185 E186 R187 N191 G192 I193	D185-T189 PolarHBondContact O-N 3.45Å; D185-T189 PolarHBondContact O-OG1 2.96Å; E186-T189 WeakPolarHBondContact O-CA 3.27Å; E186-T189 VanDerWaalsContact O-CB 3.32Å; E186-T189 WeakPolarHBondContact O-CB 3.45Å; E186-T189 PolarHBondContact O-N 3.04Å; E186-T189 VanDerWaalsContact O-N 3.08Å; R187-T189 VanDerWaalsContact C-N 3.34Å; T189-N191 PolarHBondContact O-N 3.23Å; T189-G192 PolarHBondContact O-N 3.45Å; T189-G192 VanDerWaalsContact O-N 3.16Å; T189-I193 HydrophobicContact CG2-CD1 4.1Å; T189-I193 WeakPolarHBondContact O-CG1 3.44Å; T189-I193 PolarHBondContact O-N 3.26Å
190	L	88.2	Confident	84.8	Confident	0 Å²	0	57.2 Å²	57.2	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-61	-42.1	177.2	-68.3	178.5	0	0	0	112.2	L35 R40 F43 I177 E186 R187 I193 R194	L35-L190 HydrophobicContact CD1-CD1 3.93Å; L35-L190 HydrophobicContact CD1-CD2 4.26Å; L35-L190 HydrophobicContact CD1-CG 4.49Å; R40-L190 HydrophobicContact CB-CD2 4.17Å; R40-L190 HydrophobicContact CG-CD2 4.08Å; F43-L190 HydrophobicContact CB-CD2 4.14Å; F43-L190 HydrophobicContact CD1-CB 3.89Å; F43-L190 HydrophobicContact CD1-CD2 3.78Å; F43-L190 HydrophobicContact CD1-CG 4.3Å; F43-L190 HydrophobicContact CE1-CB 3.79Å; F43-L190 HydrophobicContact CG-CD2 4.03Å; I177-L190 HydrophobicContact CG2-CD1 4.33Å; E186-L190 WeakPolarHBondContact O-CG 3.08Å; E186-L190 PolarHBondContact O-N 3.33Å; R187-L190 PolarHBondContact O-N 3.12Å; L190-I193 PolarHBondContact O-N 2.9Å; L190-R194 WeakPolarHBondContact O-CB 3.42Å; L190-R194 PolarHBondContact O-N 3.48Å
191	N	85.2	Confident	85.5	Confident	70 Å²	70	55.8 Å²	55.8	37%	0.374	29%	0.293	S	S	.	.	H	α-helix	trans	-64.1	-39.6	173.8	-81.2	-68.3	0	0	0	112.3	I177 R187 A188 T189 R194 Y195	I177-N191 WeakPolarHBondContact CD1-OD1 3.39Å; R187-N191 PolarHBondContact O-N 3.36Å; R187-N191 VanDerWaalsContact O-N 3.08Å; R187-N191 PolarHBondContact O-ND2 3.38Å; A188-N191 PolarHBondContact O-N 3.33Å; T189-N191 PolarHBondContact O-N 3.23Å; N191-R194 PolarHBondContact O-N 2.91Å; N191-Y195 PolarHBondContact O-N 3.41Å
192	G	85.2	Confident	86.1	Confident	38 Å²	38	55.8 Å²	55.8	39%	0.392	29%	0.293	S	S	.	.	H	α-helix	trans	-61.5	-44.9	174.4	0	0	0	0	0	112.4	A188 T189 Y195 A196	A188-G192 PolarHBondContact O-N 3.42Å; T189-G192 PolarHBondContact O-N 3.45Å; T189-G192 VanDerWaalsContact O-N 3.16Å; G192-Y195 PolarHBondContact O-N 2.98Å; G192-A196 PolarHBondContact O-N 2.86Å
193	I	89.8	Confident	86.9	Confident	37 Å²	37	54.4 Å²	54.4	19%	0.19	28%	0.279	C	S	.	.	H	α-helix	trans	-62.2	-46.5	176	-68.9	169	0	0	0	110.8	R40 T189 L190 Y195 A196 F197	R40-I193 HydrophobicContact CB-CD1 3.68Å; T189-I193 HydrophobicContact CG2-CD1 4.1Å; T189-I193 WeakPolarHBondContact O-CG1 3.44Å; T189-I193 PolarHBondContact O-N 3.26Å; L190-I193 PolarHBondContact O-N 2.9Å; I193-Y195 VanDerWaalsContact C-N 3.29Å; I193-Y195 PolarHBondContact O-N 3.14Å; I193-A196 WeakPolarHBondContact O-CB 3.42Å; I193-A196 PolarHBondContact O-N 2.85Å; I193-F197 HydrophobicContact CG2-CD2 3.74Å; I193-F197 HydrophobicContact CG2-CE2 3.72Å; I193-F197 WeakPolarHBondContact O-CD2 3.18Å; I193-F197 PolarHBondContact O-N 2.94Å
194	R	91.4	Very high	87.7	Confident	30 Å²	30	49.9 Å²	49.9	11%	0.113	27%	0.265	C	S	.	.	H	α-helix	trans	-53.4	-47.8	175.1	173.1	-174.5	155.9	122	7.9	111	F43 H47 H173 L174 L190 N191 F197 T198	F43-R194 HydrophobicContact CE1-CB 4.28Å; H47-R194 HydrophobicContact CB-CG 4.31Å; H47-R194 VanDerWaalsContact CD2-CZ 3.44Å; H47-R194 PolarHBondContact CD2-NH2 3.41Å; H47-R194 PolarHBondContact NE2-NH2 2.81Å; H173-R194 PolarHBondContact ND1-NH1 2.87Å; H173-R194 VanDerWaalsContact ND1-NH1 3.16Å; L174-R194 VanDerWaalsContact CD2-NH1 3.29Å; L174-R194 VanDerWaalsContact CG-NH1 3.33Å; L190-R194 WeakPolarHBondContact O-CB 3.42Å; L190-R194 PolarHBondContact O-N 3.48Å; N191-R194 PolarHBondContact O-N 2.91Å; R194-F197 PolarHBondContact O-N 2.77Å; R194-T198 PolarHBondContact O-N 3.26Å; R194-T198 PolarHBondContact O-OG1 3.42Å; R194-T198 VanDerWaalsContact O-OG1 3.11Å
195	Y	86.8	Confident	88.7	Confident	76 Å²	76	41.3 Å²	41.3	30%	0.298	23%	0.228	S	C	.	.	H	α-helix	trans	-65.1	-38.8	179.2	-174.1	-91.8	0	0	0	113	N191 G192 I193 F197 T198 V199 S348	N191-Y195 PolarHBondContact O-N 3.41Å; G192-Y195 PolarHBondContact O-N 2.98Å; I193-Y195 VanDerWaalsContact C-N 3.29Å; I193-Y195 PolarHBondContact O-N 3.14Å; Y195-F197 VanDerWaalsContact C-N 3.28Å; Y195-F197 PolarHBondContact O-N 3.37Å; Y195-T198 WeakPolarHBondContact O-CB 3.5Å; Y195-T198 PolarHBondContact O-N 2.82Å; Y195-V199 HydrophobicContact CD1-CG2 4.39Å; Y195-V199 HydrophobicContact CE1-CG2 3.87Å; Y195-V199 PolarHBondContact O-N 2.78Å; Y195-V199 VanDerWaalsContact O-N 3.12Å; Y195-S348 WeakPolarHBondContact CD1-OG 3.41Å; Y195-S348 WeakPolarHBondContact CE1-OG 3.49Å
196	A	88.8	Confident	89.7	Confident	41 Å²	41	36.4 Å²	36.4	34%	0.339	20%	0.202	S	C	.	.	H	α-helix	trans	-59.8	-40.6	174	0	0	0	0	0	111.7	G192 I193 V199 F200 F345	G192-A196 PolarHBondContact O-N 2.86Å; I193-A196 WeakPolarHBondContact O-CB 3.42Å; I193-A196 PolarHBondContact O-N 2.85Å; A196-V199 PolarHBondContact O-N 3.41Å; A196-F200 PolarHBondContact O-N 3.38Å; A196-F345 HydrophobicContact CB-CE2 4.26Å
197	F	93.6	Very high	90.4	Very high	37 Å²	37	37.8 Å²	37.8	16%	0.162	22%	0.215	C	C	.	.	H	α-helix	trans	-69.3	-33.3	174.4	-84.6	-66.3	0	0	0	113.7	V41 F45 V48 I193 R194 Y195 V199 F200 A201 F244	V41-F197 HydrophobicContact CG1-CE2 4.39Å; V41-F197 HydrophobicContact CG1-CZ 4.16Å; F45-F197 HydrophobicContact CD1-CD1 4.25Å; F45-F197 AromaticContact CD1-CE1 3.62Å; F45-F197 HydrophobicContact CD1-CE1 3.62Å; F45-F197 HydrophobicContact CD1-CE2 4.09Å; F45-F197 AromaticContact CD1-CZ 3.54Å; F45-F197 HydrophobicContact CD1-CZ 3.54Å; F45-F197 AromaticContact CE1-CE1 3.5Å; F45-F197 HydrophobicContact CE1-CE1 3.5Å; F45-F197 VanDerWaalsContact CE1-CE1 3.5Å; F45-F197 HydrophobicContact CE1-CE2 4.16Å; F45-F197 AromaticContact CE1-CZ 3.27Å; F45-F197 HydrophobicContact CE1-CZ 3.27Å; F45-F197 HydrophobicContact CZ-CZ 4.39Å; V48-F197 HydrophobicContact CG2-CB 3.78Å; V48-F197 HydrophobicContact CG2-CD1 3.71Å; V48-F197 HydrophobicContact CG2-CG 3.94Å; I193-F197 HydrophobicContact CG2-CD2 3.74Å; I193-F197 HydrophobicContact CG2-CE2 3.72Å; I193-F197 WeakPolarHBondContact O-CD2 3.18Å; I193-F197 PolarHBondContact O-N 2.94Å; R194-F197 PolarHBondContact O-N 2.77Å; Y195-F197 VanDerWaalsContact C-N 3.28Å; Y195-F197 PolarHBondContact O-N 3.37Å; F197-V199 VanDerWaalsContact C-N 3.31Å; F197-V199 PolarHBondContact O-N 3.07Å; F197-F200 HydrophobicContact CD1-CD1 4.22Å; F197-F200 PolarHBondContact O-N 2.93Å; F197-A201 WeakPolarHBondContact O-CB 3.36Å; F197-A201 PolarHBondContact O-N 3.4Å; F197-F244 HydrophobicContact CE1-CE1 4.44Å
198	T	91.9	Very high	91.1	Very high	28 Å²	28	34.9 Å²	34.9	17%	0.172	21%	0.206	C	C	.	.	H	α-helix	trans	-56.9	-46.7	170.8	-57.3	0	0	0	0	111.1	D51 R194 Y195 A201 S202	D51-T198 HydrophobicContact CB-CG2 4.12Å; D51-T198 VanDerWaalsContact CG-OG1 3.29Å; D51-T198 WeakPolarHBondContact OD2-CA 3.36Å; D51-T198 VanDerWaalsContact OD2-CB 3.28Å; D51-T198 WeakPolarHBondContact OD2-CB 3.32Å; D51-T198 PolarHBondContact OD2-OG1 2.92Å; R194-T198 PolarHBondContact O-N 3.26Å; R194-T198 PolarHBondContact O-OG1 3.42Å; R194-T198 VanDerWaalsContact O-OG1 3.11Å; Y195-T198 WeakPolarHBondContact O-CB 3.5Å; Y195-T198 PolarHBondContact O-N 2.82Å; T198-A201 WeakPolarHBondContact O-CB 3.16Å; T198-A201 PolarHBondContact O-N 2.88Å; T198-S202 PolarHBondContact O-N 2.95Å; T198-S202 PolarHBondContact O-OG 3.19Å
199	V	89.6	Confident	92	Very high	5 Å²	5	32.1 Å²	32.1	3%	0.03	18%	0.182	C	C	.	.	H	α-helix	trans	-65.8	-45	178.2	170.1	0	0	0	0	111	Y195 A196 F197 A201 S202 I203 F345	Y195-V199 HydrophobicContact CD1-CG2 4.39Å; Y195-V199 HydrophobicContact CE1-CG2 3.87Å; Y195-V199 PolarHBondContact O-N 2.78Å; Y195-V199 VanDerWaalsContact O-N 3.12Å; A196-V199 PolarHBondContact O-N 3.41Å; F197-V199 VanDerWaalsContact C-N 3.31Å; F197-V199 PolarHBondContact O-N 3.07Å; V199-A201 VanDerWaalsContact C-N 3.3Å; V199-A201 PolarHBondContact O-N 3.5Å; V199-S202 PolarHBondContact O-N 3.3Å; V199-I203 HydrophobicContact CG1-CD1 3.84Å; V199-I203 HydrophobicContact CG1-CG1 4.36Å; V199-I203 VanDerWaalsContact O-CG1 3.31Å; V199-I203 WeakPolarHBondContact O-CG1 3.34Å; V199-I203 PolarHBondContact O-N 2.88Å; V199-F345 HydrophobicContact CB-CB 4.24Å; V199-F345 HydrophobicContact CB-CD2 4.01Å; V199-F345 HydrophobicContact CB-CG 4.39Å; V199-F345 HydrophobicContact CG1-CB 3.63Å; V199-F345 HydrophobicContact CG1-CD2 3.96Å; V199-F345 HydrophobicContact CG1-CG 3.87Å; V199-F345 HydrophobicContact CG2-CB 3.78Å; V199-F345 HydrophobicContact CG2-CD2 3.87Å; V199-F345 HydrophobicContact CG2-CG 4.25Å
200	F	92.6	Very high	92.4	Very high	87 Å²	87	32.8 Å²	32.8	38%	0.382	18%	0.179	S	C	.	.	H	α-helix	trans	-54.7	-47.3	175.1	168.3	-97.6	0	0	0	111.5	A196 F197 S202 I203 V204 F244	A196-F200 PolarHBondContact O-N 3.38Å; F197-F200 HydrophobicContact CD1-CD1 4.22Å; F197-F200 PolarHBondContact O-N 2.93Å; F200-S202 PolarHBondContact O-N 2.95Å; F200-I203 PolarHBondContact O-N 3.28Å; F200-V204 HydrophobicContact CD1-CG2 4.48Å; F200-V204 HydrophobicContact CD2-CG2 4.43Å; F200-V204 HydrophobicContact CE1-CG2 4.03Å; F200-V204 HydrophobicContact CE2-CG2 3.98Å; F200-V204 HydrophobicContact CZ-CG2 3.76Å; F200-V204 WeakPolarHBondContact O-CG2 3.39Å; F200-V204 PolarHBondContact O-N 2.99Å; F200-F244 HydrophobicContact CE1-CE1 4.46Å; F200-F244 HydrophobicContact CE1-CE2 4.14Å; F200-F244 AromaticContact CE1-CZ 3.7Å; F200-F244 HydrophobicContact CE1-CZ 3.7Å; F200-F244 HydrophobicContact CZ-CZ 4.22Å
201	A	96.9	Very high	92.7	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-59.1	-47.4	176.7	0	0	0	0	0	111.7	V48 D51 L52 F197 T198 V199 I203 V204 T205	V48-A201 HydrophobicContact CG1-CB 4.31Å; D51-A201 HydrophobicContact CB-CB 3.6Å; L52-A201 HydrophobicContact CD2-CB 3.94Å; L52-A201 VanDerWaalsContact CD2-O 3.32Å; L52-A201 WeakPolarHBondContact CD2-O 3.33Å; L52-A201 HydrophobicContact CG-CB 3.82Å; F197-A201 WeakPolarHBondContact O-CB 3.36Å; F197-A201 PolarHBondContact O-N 3.4Å; T198-A201 WeakPolarHBondContact O-CB 3.16Å; T198-A201 PolarHBondContact O-N 2.88Å; V199-A201 VanDerWaalsContact C-N 3.3Å; V199-A201 PolarHBondContact O-N 3.5Å; A201-I203 VanDerWaalsContact C-N 3.34Å; A201-I203 PolarHBondContact O-N 3.39Å; A201-V204 PolarHBondContact O-N 2.92Å; A201-T205 PolarHBondContact O-N 3.3Å; A201-T205 PolarHBondContact O-OG1 3.38Å
202	S	94.6	Very high	93.2	Very high	1 Å²	1	37.7 Å²	37.7	1%	0.007	20%	0.201	C	C	.	.	H	α-helix	trans	-59.4	-43.5	176.4	-60.1	0	0	0	0	112.7	S55 T198 V199 F200 V204 T205 F206 Y341	S55-S202 VanDerWaalsContact OG-CA 3.3Å; S55-S202 WeakPolarHBondContact OG-CA 3.43Å; S55-S202 WeakPolarHBondContact OG-CB 3.16Å; S55-S202 PolarHBondContact OG-OG 2.93Å; T198-S202 PolarHBondContact O-N 2.95Å; T198-S202 PolarHBondContact O-OG 3.19Å; V199-S202 PolarHBondContact O-N 3.3Å; F200-S202 PolarHBondContact O-N 2.95Å; S202-V204 VanDerWaalsContact C-N 3.34Å; S202-V204 PolarHBondContact O-N 3.48Å; S202-T205 PolarHBondContact O-N 2.88Å; S202-F206 WeakPolarHBondContact O-CD2 3.07Å; S202-F206 WeakPolarHBondContact O-CG 3.34Å; S202-F206 PolarHBondContact O-N 3.45Å; S202-Y341 VanDerWaalsContact CB-CD1 3.47Å; S202-Y341 WeakPolarHBondContact OG-CD1 3.46Å; S202-Y341 WeakPolarHBondContact OG-CE1 3.26Å
203	I	93.4	Very high	93.5	Very high	65 Å²	65	36 Å²	36	33%	0.333	18%	0.182	S	C	.	.	H	α-helix	trans	-58.5	-47.2	175.8	-67.2	167.4	0	0	0	110.7	V199 F200 A201 F206 A207 L338	V199-I203 HydrophobicContact CG1-CD1 3.84Å; V199-I203 HydrophobicContact CG1-CG1 4.36Å; V199-I203 VanDerWaalsContact O-CG1 3.31Å; V199-I203 WeakPolarHBondContact O-CG1 3.34Å; V199-I203 PolarHBondContact O-N 2.88Å; F200-I203 PolarHBondContact O-N 3.28Å; A201-I203 VanDerWaalsContact C-N 3.34Å; A201-I203 PolarHBondContact O-N 3.39Å; I203-F206 PolarHBondContact O-N 3.39Å; I203-A207 VanDerWaalsContact O-CB 3.31Å; I203-A207 WeakPolarHBondContact O-CB 3.24Å; I203-A207 PolarHBondContact O-N 2.98Å; I203-L338 HydrophobicContact CB-CD1 4.03Å; I203-L338 HydrophobicContact CG1-CD1 3.68Å; I203-L338 HydrophobicContact CG2-CD1 4.06Å
204	V	96.2	Very high	93.3	Very high	33 Å²	33	34.5 Å²	34.5	20%	0.2	18%	0.177	C	C	.	.	H	α-helix	trans	-59.7	-49.6	178	170.5	0	0	0	0	110.6	L52 F200 A201 S202 F206 A207 L208	L52-V204 HydrophobicContact CD2-CB 3.96Å; L52-V204 HydrophobicContact CD2-CG1 3.86Å; F200-V204 HydrophobicContact CD1-CG2 4.48Å; F200-V204 HydrophobicContact CD2-CG2 4.43Å; F200-V204 HydrophobicContact CE1-CG2 4.03Å; F200-V204 HydrophobicContact CE2-CG2 3.98Å; F200-V204 HydrophobicContact CZ-CG2 3.76Å; F200-V204 WeakPolarHBondContact O-CG2 3.39Å; F200-V204 PolarHBondContact O-N 2.99Å; A201-V204 PolarHBondContact O-N 2.92Å; S202-V204 VanDerWaalsContact C-N 3.34Å; S202-V204 PolarHBondContact O-N 3.48Å; V204-F206 VanDerWaalsContact C-N 3.35Å; V204-F206 PolarHBondContact O-N 2.9Å; V204-A207 PolarHBondContact O-N 3.03Å; V204-L208 HydrophobicContact CG1-CD1 3.92Å; V204-L208 HydrophobicContact CG1-CG 4.37Å; V204-L208 VanDerWaalsContact O-CG 3.27Å; V204-L208 WeakPolarHBondContact O-CG 3.38Å; V204-L208 PolarHBondContact O-N 2.7Å
205	T	97.7	Very high	92.8	Very high	0 Å²	0	39 Å²	39	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-58	-46.1	178.9	-66.8	0	0	0	0	111.8	L52 M56 A201 S202 L208 V209	L52-T205 WeakPolarHBondContact CD2-OG1 3.41Å; L52-T205 PolarHBondContact O-OG1 3.27Å; L52-T205 VanDerWaalsContact O-OG1 3.08Å; M56-T205 HydrophobicContact CB-CG2 4.42Å; M56-T205 HydrophobicContact CG-CG2 3.36Å; A201-T205 PolarHBondContact O-N 3.3Å; A201-T205 PolarHBondContact O-OG1 3.38Å; S202-T205 PolarHBondContact O-N 2.88Å; T205-L208 PolarHBondContact O-N 2.91Å; T205-V209 WeakPolarHBondContact O-CG2 3.2Å; T205-V209 PolarHBondContact O-N 2.95Å
206	F	96.2	Very high	92.3	Very high	1 Å²	1	38.7 Å²	38.7	0%	0.004	20%	0.203	C	C	.	.	H	α-helix	trans	-69.3	-37.3	179.7	-63.1	-45.5	0	0	0	112.9	Y60 S202 I203 V204 L208 V209 Y210 A334 P337 L338 Y341	Y60-F206 AromaticContact CE2-CD1 3.75Å; Y60-F206 HydrophobicContact CE2-CD1 3.75Å; Y60-F206 AromaticContact CE2-CE1 3.76Å; Y60-F206 HydrophobicContact CE2-CE1 3.76Å; Y60-F206 AromaticContact CZ-CD1 3.79Å; Y60-F206 AromaticContact CZ-CE1 3.86Å; Y60-F206 WeakPolarHBondContact OH-CD1 3.41Å; Y60-F206 WeakPolarHBondContact OH-CE1 3.23Å; S202-F206 WeakPolarHBondContact O-CD2 3.07Å; S202-F206 WeakPolarHBondContact O-CG 3.34Å; S202-F206 PolarHBondContact O-N 3.45Å; I203-F206 PolarHBondContact O-N 3.39Å; V204-F206 VanDerWaalsContact C-N 3.35Å; V204-F206 PolarHBondContact O-N 2.9Å; F206-L208 VanDerWaalsContact C-N 3.31Å; F206-L208 PolarHBondContact O-N 3.03Å; F206-V209 PolarHBondContact O-N 3.28Å; F206-Y210 WeakPolarHBondContact O-CB 3Å; F206-Y210 PolarHBondContact O-N 3.4Å; F206-A334 WeakPolarHBondContact O-CB 3.27Å; F206-P337 HydrophobicContact CD1-CB 4.26Å; F206-P337 HydrophobicContact CE1-CB 3.73Å; F206-P337 HydrophobicContact CE2-CB 4.13Å; F206-P337 HydrophobicContact CZ-CB 3.66Å; F206-L338 HydrophobicContact CB-CB 4.08Å; F206-L338 HydrophobicContact CB-CD1 4.37Å; F206-L338 HydrophobicContact CD2-CB 4.12Å; F206-L338 HydrophobicContact CD2-CD1 4.31Å; F206-L338 HydrophobicContact CG-CB 4.35Å; F206-Y341 HydrophobicContact CD2-CD2 4.41Å; F206-Y341 AromaticContact CE2-CD2 3.35Å; F206-Y341 HydrophobicContact CE2-CD2 3.35Å; F206-Y341 AromaticContact CE2-CE2 3.54Å; F206-Y341 HydrophobicContact CE2-CE2 3.54Å; F206-Y341 HydrophobicContact CE2-CG 4.05Å; F206-Y341 AromaticContact CZ-CD2 3.91Å; F206-Y341 HydrophobicContact CZ-CD2 3.91Å; F206-Y341 AromaticContact CZ-CE2 3.63Å; F206-Y341 HydrophobicContact CZ-CE2 3.63Å
207	A	95.1	Very high	91.2	Very high	41 Å²	41	41.6 Å²	41.6	34%	0.339	23%	0.226	S	C	.	.	H	α-helix	trans	-62.3	-39.8	172.5	0	0	0	0	0	111.6	I203 V204 Y210 L211	I203-A207 VanDerWaalsContact O-CB 3.31Å; I203-A207 WeakPolarHBondContact O-CB 3.24Å; I203-A207 PolarHBondContact O-N 2.98Å; V204-A207 PolarHBondContact O-N 3.03Å; A207-Y210 WeakPolarHBondContact O-CB 3.26Å; A207-Y210 PolarHBondContact O-N 3.46Å; A207-L211 VanDerWaalsContact O-CG 3.25Å; A207-L211 WeakPolarHBondContact O-CG 3.29Å; A207-L211 PolarHBondContact O-N 2.95Å
208	L	96.9	Very high	90.2	Very high	22 Å²	22	45.6 Å²	45.6	12%	0.115	25%	0.254	C	S	.	.	H	α-helix	trans	-65	-45.5	175.9	-69.8	171.6	0	0	0	111.8	V204 T205 F206 Y210 L211 F212 V233 I236 V237	V204-L208 HydrophobicContact CG1-CD1 3.92Å; V204-L208 HydrophobicContact CG1-CG 4.37Å; V204-L208 VanDerWaalsContact O-CG 3.27Å; V204-L208 WeakPolarHBondContact O-CG 3.38Å; V204-L208 PolarHBondContact O-N 2.7Å; T205-L208 PolarHBondContact O-N 2.91Å; F206-L208 VanDerWaalsContact C-N 3.31Å; F206-L208 PolarHBondContact O-N 3.03Å; L208-Y210 VanDerWaalsContact C-N 3.3Å; L208-Y210 PolarHBondContact O-N 3.13Å; L208-L211 PolarHBondContact O-N 2.67Å; L208-F212 HydrophobicContact CD2-CD2 4.32Å; L208-F212 HydrophobicContact CD2-CE2 3.9Å; L208-F212 VanDerWaalsContact O-CD2 3.31Å; L208-F212 WeakPolarHBondContact O-CD2 3.24Å; L208-F212 PolarHBondContact O-N 3.28Å; L208-V233 HydrophobicContact CB-CG1 3.87Å; L208-V233 HydrophobicContact CB-CG2 4.07Å; L208-V233 HydrophobicContact CD1-CG1 4.47Å; L208-I236 HydrophobicContact CD1-CB 4.33Å; L208-I236 HydrophobicContact CD1-CG2 3.71Å; L208-I236 HydrophobicContact CD2-CD1 4.29Å; L208-I236 HydrophobicContact CD2-CG2 3.91Å; L208-V237 HydrophobicContact CD1-CG2 3.99Å
209	V	96.4	Very high	89.4	Confident	1 Å²	1	48.1 Å²	48.1	1%	0.006	26%	0.263	C	S	.	.	H	α-helix	trans	-62.8	-39.5	175.7	173.9	0	0	0	0	111.3	Y60 T205 F206 L211 V213 G214 V233 I333 A334	Y60-V209 HydrophobicContact CD2-CG2 3.83Å; Y60-V209 HydrophobicContact CE1-CG1 4.19Å; Y60-V209 HydrophobicContact CE2-CB 4.05Å; Y60-V209 HydrophobicContact CE2-CG1 4.1Å; Y60-V209 HydrophobicContact CE2-CG2 3.53Å; T205-V209 WeakPolarHBondContact O-CG2 3.2Å; T205-V209 PolarHBondContact O-N 2.95Å; F206-V209 PolarHBondContact O-N 3.28Å; V209-L211 VanDerWaalsContact C-N 3.34Å; V209-L211 PolarHBondContact O-N 3.11Å; V209-V213 HydrophobicContact CG1-CB 4.15Å; V209-V213 HydrophobicContact CG1-CG2 4.38Å; V209-V213 WeakPolarHBondContact O-CA 3.13Å; V209-V213 VanDerWaalsContact O-CB 3.3Å; V209-V213 WeakPolarHBondContact O-CB 3.1Å; V209-V213 PolarHBondContact O-N 3.28Å; V209-G214 PolarHBondContact O-N 3.37Å; V209-V233 HydrophobicContact CG2-CG1 3.98Å; V209-V233 HydrophobicContact CG2-CG2 4.25Å; V209-I333 HydrophobicContact CG1-CG1 4.47Å; V209-A334 HydrophobicContact CB-CB 4.48Å; V209-A334 HydrophobicContact CG1-CB 4.31Å
210	Y	94.6	Very high	89.1	Confident	75 Å²	75	51.7 Å²	51.7	29%	0.294	29%	0.288	S	S	.	.	H	α-helix	trans	-56.4	-47.9	172.9	178.3	-89.7	0	0	0	112.1	F206 A207 L208 G214 Q215 M331 A334 T335	F206-Y210 WeakPolarHBondContact O-CB 3Å; F206-Y210 PolarHBondContact O-N 3.4Å; A207-Y210 WeakPolarHBondContact O-CB 3.26Å; A207-Y210 PolarHBondContact O-N 3.46Å; L208-Y210 VanDerWaalsContact C-N 3.3Å; L208-Y210 PolarHBondContact O-N 3.13Å; Y210-G214 CarbonylContact O-C 3.35Å; Y210-G214 VanDerWaalsContact O-CA 3.23Å; Y210-G214 WeakPolarHBondContact O-CA 3.3Å; Y210-G214 PolarHBondContact O-N 3.14Å; Y210-G214 VanDerWaalsContact O-N 3.08Å; Y210-Q215 PolarHBondContact O-N 2.96Å; Y210-M331 HydrophobicContact CD2-CG 3.76Å; Y210-M331 HydrophobicContact CE2-CE 3.45Å; Y210-M331 VanDerWaalsContact CE2-CE 3.45Å; Y210-M331 HydrophobicContact CE2-CG 3.29Å; Y210-M331 HydrophobicContact CE2-SD 3.68Å; Y210-M331 WeakPolarHBondContact OH-CE 3.35Å; Y210-A334 HydrophobicContact CD2-CB 4.4Å; Y210-T335 HydrophobicContact CD2-CG2 3.81Å; Y210-T335 HydrophobicContact CE2-CG2 3.92Å
211	L	94.4	Very high	88.9	Confident	87 Å²	87	50.4 Å²	50.4	46%	0.455	29%	0.286	S	S	.	.	H	α-helix	trans	-70.3	-43.9	-176.8	-70	171.5	0	0	0	113	A207 L208 V209	A207-L211 VanDerWaalsContact O-CG 3.25Å; A207-L211 WeakPolarHBondContact O-CG 3.29Å; A207-L211 PolarHBondContact O-N 2.95Å; L208-L211 PolarHBondContact O-N 2.67Å; V209-L211 VanDerWaalsContact C-N 3.34Å; V209-L211 PolarHBondContact O-N 3.11Å
212	F	94.5	Very high	88.6	Confident	87 Å²	87	50.6 Å²	50.6	38%	0.382	29%	0.286	S	S	.	.	H	α-helix	trans	-96.8	-15	-170.9	-71.2	-74.2	0	0	0	114.9	L208 G229 T232 V233 I236	L208-F212 HydrophobicContact CD2-CD2 4.32Å; L208-F212 HydrophobicContact CD2-CE2 3.9Å; L208-F212 VanDerWaalsContact O-CD2 3.31Å; L208-F212 WeakPolarHBondContact O-CD2 3.24Å; L208-F212 PolarHBondContact O-N 3.28Å; F212-G229 WeakPolarHBondContact O-CA 3.4Å; F212-T232 HydrophobicContact CD1-CG2 3.71Å; F212-T232 HydrophobicContact CD2-CG2 4.48Å; F212-T232 HydrophobicContact CE1-CG2 3.61Å; F212-T232 HydrophobicContact CE2-CG2 4.41Å; F212-T232 HydrophobicContact CG-CG2 4.17Å; F212-T232 HydrophobicContact CZ-CG2 3.98Å; F212-V233 HydrophobicContact CB-CG2 3.81Å; F212-V233 HydrophobicContact CD2-CG2 4Å; F212-V233 HydrophobicContact CG-CG2 4.25Å; F212-I236 HydrophobicContact CD2-CD1 4.26Å; F212-I236 HydrophobicContact CE1-CD1 4.5Å; F212-I236 HydrophobicContact CE2-CD1 3.39Å; F212-I236 HydrophobicContact CZ-CD1 3.54Å
213	V	92.3	Very high	88.5	Confident	1 Å²	1	52 Å²	52	1%	0.006	30%	0.295	C	S	.	.	T	Hydrogen-bonded Turn	trans	-125.2	-38.3	-179.8	-178.4	0	0	0	0	110.9	V209 Q215 D226 F230 K330	V209-V213 HydrophobicContact CG1-CB 4.15Å; V209-V213 HydrophobicContact CG1-CG2 4.38Å; V209-V213 WeakPolarHBondContact O-CA 3.13Å; V209-V213 VanDerWaalsContact O-CB 3.3Å; V209-V213 WeakPolarHBondContact O-CB 3.1Å; V209-V213 PolarHBondContact O-N 3.28Å; V213-Q215 PolarHBondContact O-N 3.4Å; V213-D226 HydrophobicContact CG1-CB 4.19Å; V213-F230 HydrophobicContact CG1-CE2 3.83Å; V213-F230 HydrophobicContact CG1-CZ 4.04Å; V213-F230 HydrophobicContact CG2-CD1 4.4Å; V213-F230 HydrophobicContact CG2-CD2 4.05Å; V213-F230 HydrophobicContact CG2-CE1 4.4Å; V213-F230 HydrophobicContact CG2-CE2 4.08Å; V213-F230 HydrophobicContact CG2-CG 4.22Å; V213-F230 HydrophobicContact CG2-CZ 4.25Å; V213-K330 WeakPolarHBondContact O-CD 3.14Å; V213-K330 WeakPolarHBondContact O-CE 3.45Å; V213-K330 PolarHBondContact O-NZ 2.91Å; V213-K330 VanDerWaalsContact O-NZ 3.16Å
214	G	84.8	Confident	88.4	Confident	7 Å²	7	51 Å²	51	7%	0.072	29%	0.293	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.5	-20.9	-174.1	0	0	0	0	0	115.7	V209 Y210	V209-G214 PolarHBondContact O-N 3.37Å; Y210-G214 CarbonylContact O-C 3.35Å; Y210-G214 VanDerWaalsContact O-CA 3.23Å; Y210-G214 WeakPolarHBondContact O-CA 3.3Å; Y210-G214 PolarHBondContact O-N 3.14Å; Y210-G214 VanDerWaalsContact O-N 3.08Å
215	Q	80.6	Confident	88.1	Confident	124 Å²	124	56.9 Å²	56.9	58%	0.579	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.3	-5.9	-170.8	-70.3	-160.9	-28.6	0	0	116	Y210 V213 A217	Y210-Q215 PolarHBondContact O-N 2.96Å; V213-Q215 PolarHBondContact O-N 3.4Å; Q215-A217 PolarHBondContact O-N 3.27Å
216	D	76.9	Confident	87.9	Confident	70 Å²	70	57 Å²	57	37%	0.374	32%	0.319	S	S	.	.			trans	-69.8	103.4	180	-58.7	-39.5	0	0	0	111.1	V218 K330	D216-V218 PolarHBondContact O-N 2.91Å; D216-V218 VanDerWaalsContact O-N 3.16Å; D216-K330 VanDerWaalsContact CB-NZ 3.33Å; D216-K330 IonicContact OD2-NZ 3.44Å; D216-K330 PolarHBondContact OD2-NZ 3.39Å
217	A	66.1	Low	87.9	Confident	101 Å²	101	57.3 Å²	57.3	84%	0.835	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.4	-16	177.2	0	0	0	0	0	113.4	Q215	Q215-A217 PolarHBondContact O-N 3.27Å
218	V	71.6	Confident	87.8	Confident	122 Å²	122	60.2 Å²	60.2	74%	0.739	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.4	-37.5	-175	-176.4	0	0	0	0	112.1	D216	D216-V218 PolarHBondContact O-N 2.91Å; D216-V218 VanDerWaalsContact O-N 3.16Å
219	H	76.8	Confident	87.8	Confident	81 Å²	81	59.6 Å²	59.6	38%	0.375	33%	0.333	S	S	.	.			trans	-121.3	119.4	-175	-63.6	-55.4	0	0	0	110.4	T223 K330	H219-T223 HydrophobicContact CB-CG2 4.26Å; H219-K330 VanDerWaalsContact O-CE 3.28Å; H219-K330 WeakPolarHBondContact O-CE 3.37Å
220	S	82.4	Confident	87.8	Confident	80 Å²	80	59.5 Å²	59.5	56%	0.559	33%	0.333	S	S	*	.	S	Bend	trans	-76.7	-22.9	178.3	-63.1	0	0	0	0	113.4	N329 K330	S220-N329 CarbonylContact O-C 3.46Å; S220-N329 WeakPolarHBondContact O-CA 3.38Å; S220-K330 PolarHBondContact O-N 3.18Å
221	D	87.8	Confident	87.9	Confident	60 Å²	60	56.9 Å²	56.9	32%	0.321	33%	0.325	S	S	.	.	S	Bend	trans	-105.7	162.4	177.2	-165.3	8.8	0	0	0	110.6	K67	K67-D221 IonicContact NZ-OD1 3.61Å; K67-D221 PolarHBondContact NZ-OD1 3.32Å; K67-D221 IonicContact NZ-OD2 2.96Å; K67-D221 PolarHBondContact NZ-OD2 2.84Å
222	V	91.7	Very high	88.1	Confident	3 Å²	3	54.8 Å²	54.8	2%	0.018	32%	0.317	C	S	.	.			trans	-73.7	131.9	171.3	-179.6	0	0	0	0	109.3	V63 K67 V68 D226 F230 L323 K330 I333	V63-V222 HydrophobicContact CG1-CB 4.35Å; V63-V222 HydrophobicContact CG1-CG1 4.12Å; V63-V222 HydrophobicContact CG1-CG2 4.14Å; K67-V222 HydrophobicContact CB-CB 3.87Å; K67-V222 HydrophobicContact CB-CG1 3.69Å; K67-V222 HydrophobicContact CG-CB 4.25Å; V68-V222 HydrophobicContact CG2-CG1 3.73Å; V222-D226 WeakPolarHBondContact CA-OD2 3.41Å; V222-D226 HydrophobicContact CG1-CB 4.16Å; V222-F230 HydrophobicContact CG1-CE2 3.9Å; V222-L323 HydrophobicContact CB-CD1 4.27Å; V222-L323 HydrophobicContact CG2-CD1 3.77Å; V222-L323 HydrophobicContact CG2-CD2 4.39Å; V222-K330 HydrophobicContact CG2-CB 3.87Å; V222-K330 HydrophobicContact CG2-CD 4.48Å; V222-I333 HydrophobicContact CG2-CD1 3.66Å
223	T	91.5	Very high	88.2	Confident	30 Å²	30	50.7 Å²	50.7	18%	0.184	30%	0.298	C	S	.	.			trans	-130.1	169.8	-173.8	66.6	0	0	0	0	111.3	K67 H219 H225 D226	K67-T223 CarbonylContact O-C 3.56Å; H219-T223 HydrophobicContact CB-CG2 4.26Å; T223-H225 PolarHBondContact O-N 2.88Å; T223-H225 PolarHBondContact OG1-N 3.3Å; T223-D226 PolarHBondContact N-OD2 3.45Å; T223-D226 WeakPolarHBondContact O-CB 3.45Å; T223-D226 PolarHBondContact O-N 3.02Å; T223-D226 PolarHBondContact OG1-OD2 3.27Å; T223-D226 VanDerWaalsContact OG1-OD2 3.14Å
224	P	91.3	Very high	88.5	Confident	46 Å²	46	50.6 Å²	50.6	30%	0.299	30%	0.298	S	S	.	.	G	3₁₀ helix	trans	-56.6	-20.4	170.9	-28.6	37.2	0	0	0	115	K67 V68 L70 R134 D226 A227	K67-P224 WeakPolarHBondContact O-CD 3.36Å; V68-P224 WeakPolarHBondContact O-CB 3.28Å; L70-P224 HydrophobicContact CD1-CG 3.92Å; L70-P224 HydrophobicContact CD2-CG 4.05Å; L70-P224 HydrophobicContact CG-CG 3.99Å; R134-P224 PolarHBondContact NH2-O 3.5Å; P224-D226 VanDerWaalsContact C-N 3.28Å; P224-D226 PolarHBondContact O-N 3.34Å; P224-A227 WeakPolarHBondContact O-CB 3.47Å; P224-A227 PolarHBondContact O-N 3.44Å
225	H	90.7	Very high	89.1	Confident	156 Å²	156	55.1 Å²	55.1	72%	0.722	32%	0.316	S	S	*	.	G	3₁₀ helix	trans	-67.8	-27.6	175.1	-98.9	-80	0	0	0	112.8	T223 A227	T223-H225 PolarHBondContact O-N 2.88Å; T223-H225 PolarHBondContact OG1-N 3.3Å; H225-A227 PolarHBondContact O-N 2.89Å; H225-A227 VanDerWaalsContact O-N 3.11Å
226	D	93.9	Very high	90	Very high	3 Å²	3	51.9 Å²	51.9	2%	0.016	30%	0.302	C	S	.	.	G	3₁₀ helix	trans	-70.8	-3.8	179.7	-66.6	-72.4	0	0	0	113.8	V68 V213 V222 T223 P224 V228 G229 F230 K330	V68-D226 HydrophobicContact CG2-CB 4.35Å; V213-D226 HydrophobicContact CG1-CB 4.19Å; V222-D226 WeakPolarHBondContact CA-OD2 3.41Å; V222-D226 HydrophobicContact CG1-CB 4.16Å; T223-D226 PolarHBondContact N-OD2 3.45Å; T223-D226 WeakPolarHBondContact O-CB 3.45Å; T223-D226 PolarHBondContact O-N 3.02Å; T223-D226 PolarHBondContact OG1-OD2 3.27Å; T223-D226 VanDerWaalsContact OG1-OD2 3.14Å; P224-D226 VanDerWaalsContact C-N 3.28Å; P224-D226 PolarHBondContact O-N 3.34Å; D226-V228 PolarHBondContact O-N 3.04Å; D226-G229 WeakPolarHBondContact O-CA 3.4Å; D226-G229 PolarHBondContact O-N 3.15Å; D226-F230 HydrophobicContact CB-CD2 4.17Å; D226-F230 HydrophobicContact CB-CE2 4.16Å; D226-F230 WeakPolarHBondContact O-CD2 3.37Å; D226-F230 PolarHBondContact O-N 2.99Å; D226-K330 IonicContact OD1-NZ 3.36Å; D226-K330 PolarHBondContact OD1-NZ 2.82Å; D226-K330 IonicContact OD2-NZ 2.67Å; D226-K330 PolarHBondContact OD2-NZ 3.23Å
227	A	94.5	Very high	91	Very high	7 Å²	7	48.6 Å²	48.6	6%	0.058	28%	0.284	C	S	.	.	H	α-helix	trans	-54.4	-38	179.2	0	0	0	0	0	113.1	V68 R134 P224 H225 S231	V68-A227 HydrophobicContact CG1-CB 3.44Å; V68-A227 VanDerWaalsContact CG1-CB 3.44Å; R134-A227 HydrophobicContact CG-CB 4.28Å; P224-A227 WeakPolarHBondContact O-CB 3.47Å; P224-A227 PolarHBondContact O-N 3.44Å; H225-A227 PolarHBondContact O-N 2.89Å; H225-A227 VanDerWaalsContact O-N 3.11Å; A227-S231 WeakPolarHBondContact O-CB 3.29Å; A227-S231 PolarHBondContact O-N 3.4Å; A227-S231 PolarHBondContact O-OG 2.99Å
228	V	94.7	Very high	92.5	Very high	101 Å²	101	44.1 Å²	44.1	61%	0.612	25%	0.247	S	C	*	.	H	α-helix	trans	-71.1	-38.2	178.8	-179.3	0	0	0	0	110.7	D226 S231 T232	D226-V228 PolarHBondContact O-N 3.04Å; V228-S231 WeakPolarHBondContact CA-OG 3.21Å; V228-S231 PolarHBondContact O-OG 3.29Å; V228-T232 VanDerWaalsContact O-CB 3.28Å; V228-T232 WeakPolarHBondContact O-CB 3.4Å; V228-T232 PolarHBondContact O-N 3.47Å; V228-T232 PolarHBondContact O-OG1 2.84Å
229	G	95.3	Very high	93.8	Very high	9 Å²	9	40.2 Å²	40.2	9%	0.093	23%	0.231	C	C	.	.	H	α-helix	trans	-59.9	-53.1	174.5	0	0	0	0	0	111.7	F212 D226 S231 T232 V233	F212-G229 WeakPolarHBondContact O-CA 3.4Å; D226-G229 WeakPolarHBondContact O-CA 3.4Å; D226-G229 PolarHBondContact O-N 3.15Å; G229-S231 PolarHBondContact O-N 2.8Å; G229-T232 PolarHBondContact O-N 2.88Å; G229-V233 WeakPolarHBondContact O-CG2 3.47Å; G229-V233 PolarHBondContact O-N 3.19Å
230	F	97.2	Very high	94.8	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-61.3	-43.1	178	-79.6	-73.6	0	0	0	113.4	Y60 V63 F64 V68 F132 V213 V222 D226 T232 V233 G234	Y60-F230 HydrophobicContact CD1-CE1 4.32Å; Y60-F230 HydrophobicContact CG-CE1 4.04Å; V63-F230 HydrophobicContact CG1-CZ 4.24Å; F64-F230 HydrophobicContact CD2-CB 3.63Å; F64-F230 HydrophobicContact CD2-CD1 4.46Å; F64-F230 AromaticContact CD2-CD2 3.86Å; F64-F230 HydrophobicContact CD2-CD2 3.86Å; F64-F230 AromaticContact CD2-CG 3.73Å; F64-F230 HydrophobicContact CD2-CG 3.73Å; F64-F230 HydrophobicContact CE2-CB 3.79Å; F64-F230 HydrophobicContact CE2-CG 4.35Å; V68-F230 HydrophobicContact CG2-CD2 3.85Å; V68-F230 HydrophobicContact CG2-CE2 3.87Å; F132-F230 HydrophobicContact CB-CB 4.49Å; F132-F230 HydrophobicContact CD1-CB 4.44Å; F132-F230 HydrophobicContact CD1-CD1 4.28Å; V213-F230 HydrophobicContact CG1-CE2 3.83Å; V213-F230 HydrophobicContact CG1-CZ 4.04Å; V213-F230 HydrophobicContact CG2-CD1 4.4Å; V213-F230 HydrophobicContact CG2-CD2 4.05Å; V213-F230 HydrophobicContact CG2-CE1 4.4Å; V213-F230 HydrophobicContact CG2-CE2 4.08Å; V213-F230 HydrophobicContact CG2-CG 4.22Å; V213-F230 HydrophobicContact CG2-CZ 4.25Å; V222-F230 HydrophobicContact CG1-CE2 3.9Å; D226-F230 HydrophobicContact CB-CD2 4.17Å; D226-F230 HydrophobicContact CB-CE2 4.16Å; D226-F230 WeakPolarHBondContact O-CD2 3.37Å; D226-F230 PolarHBondContact O-N 2.99Å; F230-T232 VanDerWaalsContact C-N 3.35Å; F230-T232 PolarHBondContact O-N 3.26Å; F230-V233 PolarHBondContact O-N 3.44Å; F230-G234 PolarHBondContact O-N 3.38Å
231	S	97.2	Very high	95.6	Very high	19 Å²	19	34.9 Å²	34.9	13%	0.133	20%	0.201	C	C	.	.	H	α-helix	trans	-65.9	-38.6	177.8	55	0	0	0	0	111.9	F132 A227 V228 G229 G234 F235	F132-S231 VanDerWaalsContact O-CA 3.24Å; F132-S231 WeakPolarHBondContact O-CA 3.26Å; F132-S231 VanDerWaalsContact O-CB 3.25Å; F132-S231 WeakPolarHBondContact O-CB 3.28Å; F132-S231 PolarHBondContact O-N 3.23Å; A227-S231 WeakPolarHBondContact O-CB 3.29Å; A227-S231 PolarHBondContact O-N 3.4Å; A227-S231 PolarHBondContact O-OG 2.99Å; V228-S231 WeakPolarHBondContact CA-OG 3.21Å; V228-S231 PolarHBondContact O-OG 3.29Å; G229-S231 PolarHBondContact O-N 2.8Å; S231-G234 PolarHBondContact O-N 3.03Å; S231-F235 WeakPolarHBondContact O-CD2 3.45Å; S231-F235 PolarHBondContact O-N 3.05Å
232	T	97.8	Very high	96.1	Very high	44 Å²	44	34.4 Å²	34.4	27%	0.27	20%	0.198	S	C	.	.	H	α-helix	trans	-60.5	-46.3	174.2	-59.1	0	0	0	0	111.2	F212 V228 G229 F230 G234 F235 I236	F212-T232 HydrophobicContact CD1-CG2 3.71Å; F212-T232 HydrophobicContact CD2-CG2 4.48Å; F212-T232 HydrophobicContact CE1-CG2 3.61Å; F212-T232 HydrophobicContact CE2-CG2 4.41Å; F212-T232 HydrophobicContact CG-CG2 4.17Å; F212-T232 HydrophobicContact CZ-CG2 3.98Å; V228-T232 VanDerWaalsContact O-CB 3.28Å; V228-T232 WeakPolarHBondContact O-CB 3.4Å; V228-T232 PolarHBondContact O-N 3.47Å; V228-T232 PolarHBondContact O-OG1 2.84Å; G229-T232 PolarHBondContact O-N 2.88Å; F230-T232 VanDerWaalsContact C-N 3.35Å; F230-T232 PolarHBondContact O-N 3.26Å; T232-G234 VanDerWaalsContact C-N 3.33Å; T232-G234 PolarHBondContact O-N 3.45Å; T232-F235 PolarHBondContact O-N 2.89Å; T232-I236 HydrophobicContact CG2-CD1 3.83Å; T232-I236 HydrophobicContact CG2-CG1 4.48Å; T232-I236 VanDerWaalsContact O-CG1 3.31Å; T232-I236 WeakPolarHBondContact O-CG1 3.48Å; T232-I236 PolarHBondContact O-N 3.39Å
233	V	97.9	Very high	96.4	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-59.7	-45.1	174	178	0	0	0	0	110.6	M56 L208 V209 F212 G229 F230 F235 I236 V237	M56-V233 HydrophobicContact CE-CB 4.16Å; M56-V233 HydrophobicContact CE-CG1 3.76Å; M56-V233 HydrophobicContact SD-CG1 3.81Å; L208-V233 HydrophobicContact CB-CG1 3.87Å; L208-V233 HydrophobicContact CB-CG2 4.07Å; L208-V233 HydrophobicContact CD1-CG1 4.47Å; V209-V233 HydrophobicContact CG2-CG1 3.98Å; V209-V233 HydrophobicContact CG2-CG2 4.25Å; F212-V233 HydrophobicContact CB-CG2 3.81Å; F212-V233 HydrophobicContact CD2-CG2 4Å; F212-V233 HydrophobicContact CG-CG2 4.25Å; G229-V233 WeakPolarHBondContact O-CG2 3.47Å; G229-V233 PolarHBondContact O-N 3.19Å; F230-V233 PolarHBondContact O-N 3.44Å; V233-F235 VanDerWaalsContact C-N 3.34Å; V233-F235 PolarHBondContact O-N 3.49Å; V233-I236 PolarHBondContact O-N 3.23Å; V233-V237 HydrophobicContact CG1-CG2 4.15Å; V233-V237 WeakPolarHBondContact O-CB 3.43Å; V233-V237 WeakPolarHBondContact O-CG2 3.29Å; V233-V237 PolarHBondContact O-N 2.94Å
234	G	98.1	Very high	96.7	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-57.8	-43	177.6	0	0	0	0	0	113	F230 S231 T232 T238	F230-G234 PolarHBondContact O-N 3.38Å; S231-G234 PolarHBondContact O-N 3.03Å; T232-G234 VanDerWaalsContact C-N 3.33Å; T232-G234 PolarHBondContact O-N 3.45Å; G234-T238 VanDerWaalsContact O-CB 3.28Å; G234-T238 WeakPolarHBondContact O-CB 3.45Å; G234-T238 PolarHBondContact O-N 3.3Å; G234-T238 PolarHBondContact O-OG1 3.46Å
235	F	98.1	Very high	97	Very high	102 Å²	102	34.6 Å²	34.6	45%	0.447	20%	0.2	S	C	.	.	H	α-helix	trans	-68.5	-42.1	176.1	-78.8	-64.5	0	0	0	112.9	A129 M133 S231 T232 V233 T238 G239	A129-F235 HydrophobicContact CB-CD1 3.95Å; A129-F235 HydrophobicContact CB-CE1 3.96Å; M133-F235 HydrophobicContact CE-CE2 3.9Å; M133-F235 HydrophobicContact CE-CZ 3.81Å; M133-F235 HydrophobicContact CG-CE2 4.26Å; M133-F235 HydrophobicContact SD-CE1 4.41Å; M133-F235 HydrophobicContact SD-CE2 3.62Å; M133-F235 HydrophobicContact SD-CZ 3.37Å; M133-F235 WeakPolarHBondContact SD-CZ 3.4Å; S231-F235 WeakPolarHBondContact O-CD2 3.45Å; S231-F235 PolarHBondContact O-N 3.05Å; T232-F235 PolarHBondContact O-N 2.89Å; V233-F235 VanDerWaalsContact C-N 3.34Å; V233-F235 PolarHBondContact O-N 3.49Å; F235-T238 WeakPolarHBondContact O-CB 3.45Å; F235-T238 PolarHBondContact O-N 2.87Å; F235-G239 PolarHBondContact O-N 3.22Å
236	I	98.3	Very high	97.3	Very high	56 Å²	56	31.2 Å²	31.2	29%	0.287	19%	0.187	S	C	.	.	H	α-helix	trans	-65	-46.8	177.6	-67	168.9	0	0	0	110.4	L208 F212 T232 V233 T238 G239 V240	L208-I236 HydrophobicContact CD1-CB 4.33Å; L208-I236 HydrophobicContact CD1-CG2 3.71Å; L208-I236 HydrophobicContact CD2-CD1 4.29Å; L208-I236 HydrophobicContact CD2-CG2 3.91Å; F212-I236 HydrophobicContact CD2-CD1 4.26Å; F212-I236 HydrophobicContact CE1-CD1 4.5Å; F212-I236 HydrophobicContact CE2-CD1 3.39Å; F212-I236 HydrophobicContact CZ-CD1 3.54Å; T232-I236 HydrophobicContact CG2-CD1 3.83Å; T232-I236 HydrophobicContact CG2-CG1 4.48Å; T232-I236 VanDerWaalsContact O-CG1 3.31Å; T232-I236 WeakPolarHBondContact O-CG1 3.48Å; T232-I236 PolarHBondContact O-N 3.39Å; V233-I236 PolarHBondContact O-N 3.23Å; I236-T238 VanDerWaalsContact C-N 3.28Å; I236-T238 PolarHBondContact O-N 3.36Å; I236-G239 PolarHBondContact O-N 2.94Å; I236-V240 HydrophobicContact CG2-CG2 4.06Å; I236-V240 WeakPolarHBondContact O-CB 3.44Å; I236-V240 WeakPolarHBondContact O-CG2 3.43Å; I236-V240 PolarHBondContact O-N 3.46Å
237	V	98.2	Very high	97.5	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-56.4	-44.7	174.9	159	0	0	0	0	110.9	L52 M56 F128 L208 V233 G241	L52-V237 HydrophobicContact CB-CG1 3.58Å; L52-V237 HydrophobicContact CB-CG2 4.42Å; L52-V237 HydrophobicContact CD1-CG1 4.45Å; M56-V237 HydrophobicContact SD-CB 4.28Å; M56-V237 HydrophobicContact SD-CG1 4.44Å; M56-V237 HydrophobicContact SD-CG2 3.96Å; F128-V237 HydrophobicContact CD1-CG1 4.33Å; F128-V237 HydrophobicContact CE1-CB 4.39Å; F128-V237 HydrophobicContact CE1-CG1 3.67Å; F128-V237 HydrophobicContact CZ-CG1 4.43Å; L208-V237 HydrophobicContact CD1-CG2 3.99Å; V233-V237 HydrophobicContact CG1-CG2 4.15Å; V233-V237 WeakPolarHBondContact O-CB 3.43Å; V233-V237 WeakPolarHBondContact O-CG2 3.29Å; V233-V237 PolarHBondContact O-N 2.94Å; V237-G241 WeakPolarHBondContact O-CA 3.49Å; V237-G241 PolarHBondContact O-N 3.29Å
238	T	98.3	Very high	97.6	Very high	7 Å²	7	34.2 Å²	34.2	4%	0.043	20%	0.201	C	C	.	.	H	α-helix	trans	-59.7	-47.4	175.9	-63.6	0	0	0	0	111.6	Y49 F125 G234 F235 I236 L242	Y49-T238 WeakPolarHBondContact OH-CG2 3.39Å; F125-T238 HydrophobicContact CD2-CG2 3.61Å; F125-T238 HydrophobicContact CE2-CG2 4Å; G234-T238 VanDerWaalsContact O-CB 3.28Å; G234-T238 WeakPolarHBondContact O-CB 3.45Å; G234-T238 PolarHBondContact O-N 3.3Å; G234-T238 PolarHBondContact O-OG1 3.46Å; F235-T238 WeakPolarHBondContact O-CB 3.45Å; F235-T238 PolarHBondContact O-N 2.87Å; I236-T238 VanDerWaalsContact C-N 3.28Å; I236-T238 PolarHBondContact O-N 3.36Å; T238-L242 VanDerWaalsContact O-CB 3.28Å; T238-L242 WeakPolarHBondContact O-CB 3.45Å; T238-L242 PolarHBondContact O-N 3.29Å
239	G	98.1	Very high	97.6	Very high	40 Å²	40	30.2 Å²	30.2	41%	0.412	18%	0.176	S	C	.	.	H	α-helix	trans	-67.8	-46.6	-179.9	0	0	0	0	0	113.6	F235 I236 L242 A243	F235-G239 PolarHBondContact O-N 3.22Å; I236-G239 PolarHBondContact O-N 2.94Å; G239-L242 PolarHBondContact O-N 3.11Å; G239-A243 PolarHBondContact O-N 3.09Å
240	V	98.2	Very high	97.5	Very high	50 Å²	50	36 Å²	36	30%	0.303	21%	0.205	S	C	.	.	H	α-helix	trans	-63.5	-47.7	176.7	172.8	0	0	0	0	110.1	L52 I236 L242 A243 F244	L52-V240 HydrophobicContact CD1-CB 4.46Å; L52-V240 HydrophobicContact CD1-CG1 4.13Å; I236-V240 HydrophobicContact CG2-CG2 4.06Å; I236-V240 WeakPolarHBondContact O-CB 3.44Å; I236-V240 WeakPolarHBondContact O-CG2 3.43Å; I236-V240 PolarHBondContact O-N 3.46Å; V240-L242 VanDerWaalsContact C-N 3.34Å; V240-L242 PolarHBondContact O-N 3.3Å; V240-A243 WeakPolarHBondContact O-CB 3.43Å; V240-A243 PolarHBondContact O-N 2.99Å; V240-A243 VanDerWaalsContact O-N 3.12Å; V240-F244 HydrophobicContact CG1-CD2 3.79Å; V240-F244 HydrophobicContact CG1-CE2 3.77Å; V240-F244 WeakPolarHBondContact O-CD2 3.46Å; V240-F244 PolarHBondContact O-N 2.93Å
241	G	98.4	Very high	97.2	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-57.8	-44.7	177.1	0	0	0	0	0	112.4	V237 A243 F244 S245	V237-G241 WeakPolarHBondContact O-CA 3.49Å; V237-G241 PolarHBondContact O-N 3.29Å; G241-A243 VanDerWaalsContact C-N 3.34Å; G241-A243 PolarHBondContact O-N 2.8Å; G241-F244 PolarHBondContact O-N 3.39Å; G241-S245 PolarHBondContact O-N 3.47Å; G241-S245 PolarHBondContact O-OG 2.02Å
242	L	98.1	Very high	96.8	Very high	49 Å²	49	35.7 Å²	35.7	26%	0.257	20%	0.203	S	C	.	.	H	α-helix	trans	-60.3	-41.9	174.4	-178.1	62.6	0	0	0	112.2	T121 F125 T238 G239 V240 S245 I246	T121-L242 HydrophobicContact CG2-CD1 4.17Å; F125-L242 HydrophobicContact CD2-CD2 4.03Å; F125-L242 HydrophobicContact CE2-CD2 3.96Å; T238-L242 VanDerWaalsContact O-CB 3.28Å; T238-L242 WeakPolarHBondContact O-CB 3.45Å; T238-L242 PolarHBondContact O-N 3.29Å; G239-L242 PolarHBondContact O-N 3.11Å; V240-L242 VanDerWaalsContact C-N 3.34Å; V240-L242 PolarHBondContact O-N 3.3Å; L242-S245 PolarHBondContact O-N 3.46Å; L242-I246 HydrophobicContact CD1-CD1 4.45Å; L242-I246 HydrophobicContact CG-CD1 4.11Å; L242-I246 VanDerWaalsContact O-CG1 3.3Å; L242-I246 WeakPolarHBondContact O-CG1 3.42Å; L242-I246 PolarHBondContact O-N 3.01Å
243	A	98.2	Very high	96	Very high	49 Å²	49	42.8 Å²	42.8	41%	0.405	23%	0.225	S	C	.	.	H	α-helix	trans	-61	-44.9	176.4	0	0	0	0	0	111.8	G239 V240 G241 I246 L247	G239-A243 PolarHBondContact O-N 3.09Å; V240-A243 WeakPolarHBondContact O-CB 3.43Å; V240-A243 PolarHBondContact O-N 2.99Å; V240-A243 VanDerWaalsContact O-N 3.12Å; G241-A243 VanDerWaalsContact C-N 3.34Å; G241-A243 PolarHBondContact O-N 2.8Å; A243-I246 PolarHBondContact O-N 2.9Å; A243-L247 WeakPolarHBondContact O-CG 3.19Å; A243-L247 PolarHBondContact O-N 3.47Å
244	F	98.3	Very high	94.9	Very high	33 Å²	33	44.8 Å²	44.8	15%	0.145	24%	0.235	C	C	.	.	H	α-helix	trans	-63.2	-41.6	174.4	-85.5	-85.1	0	0	0	112.5	F45 V48 F197 F200 V240 G241 I246 L247 F248	F45-F244 HydrophobicContact CB-CD1 3.93Å; F45-F244 AromaticContact CD1-CD1 3.46Å; F45-F244 HydrophobicContact CD1-CD1 3.46Å; F45-F244 VanDerWaalsContact CD1-CD1 3.46Å; F45-F244 AromaticContact CD1-CE1 3.55Å; F45-F244 HydrophobicContact CD1-CE1 3.55Å; F45-F244 HydrophobicContact CE1-CD1 4.04Å; F45-F244 AromaticContact CE1-CE1 3.69Å; F45-F244 HydrophobicContact CE1-CE1 3.69Å; F45-F244 AromaticContact CG-CD1 3.77Å; F45-F244 HydrophobicContact CG-CD1 3.77Å; F45-F244 HydrophobicContact CG-CE1 4.28Å; V48-F244 HydrophobicContact CB-CB 3.99Å; V48-F244 HydrophobicContact CB-CD1 4.18Å; V48-F244 HydrophobicContact CB-CG 4.02Å; V48-F244 HydrophobicContact CG1-CB 4.06Å; V48-F244 HydrophobicContact CG1-CD1 4.12Å; V48-F244 HydrophobicContact CG1-CD2 3.8Å; V48-F244 HydrophobicContact CG1-CE2 4.27Å; V48-F244 HydrophobicContact CG1-CG 3.73Å; V48-F244 HydrophobicContact CG2-CD1 3.98Å; V48-F244 HydrophobicContact CG2-CE1 4.42Å; V48-F244 HydrophobicContact CG2-CG 4.33Å; F197-F244 HydrophobicContact CE1-CE1 4.44Å; F200-F244 HydrophobicContact CE1-CE1 4.46Å; F200-F244 HydrophobicContact CE1-CE2 4.14Å; F200-F244 AromaticContact CE1-CZ 3.7Å; F200-F244 HydrophobicContact CE1-CZ 3.7Å; F200-F244 HydrophobicContact CZ-CZ 4.22Å; V240-F244 HydrophobicContact CG1-CD2 3.79Å; V240-F244 HydrophobicContact CG1-CE2 3.77Å; V240-F244 WeakPolarHBondContact O-CD2 3.46Å; V240-F244 PolarHBondContact O-N 2.93Å; G241-F244 PolarHBondContact O-N 3.39Å; F244-I246 VanDerWaalsContact C-N 3.33Å; F244-I246 PolarHBondContact O-N 2.84Å; F244-L247 PolarHBondContact O-N 3.17Å; F244-F248 PolarHBondContact O-N 3.37Å
245	S	97.7	Very high	93.2	Very high	1 Å²	1	49.7 Å²	49.7	1%	0.007	26%	0.264	C	S	.	.	H	α-helix	trans	-60.4	-42.1	174.1	-69.5	0	0	0	0	111.7	G241 L242 F248 H249	G241-S245 PolarHBondContact O-N 3.47Å; G241-S245 PolarHBondContact O-OG 2.02Å; L242-S245 PolarHBondContact O-N 3.46Å; S245-F248 WeakPolarHBondContact O-CB 3.41Å; S245-F248 PolarHBondContact O-N 2.92Å; S245-H249 WeakPolarHBondContact O-CB 3.48Å; S245-H249 PolarHBondContact O-CD2 2.93Å; S245-H249 PolarHBondContact O-N 3.11Å
246	I	97.2	Very high	91.1	Very high	85 Å²	85	52 Å²	52	44%	0.436	27%	0.27	S	S	.	.	H	α-helix	trans	-61.1	-46.9	175	-68.9	164.9	0	0	0	110.4	L242 A243 F244 F248 H249 L250	L242-I246 HydrophobicContact CD1-CD1 4.45Å; L242-I246 HydrophobicContact CG-CD1 4.11Å; L242-I246 VanDerWaalsContact O-CG1 3.3Å; L242-I246 WeakPolarHBondContact O-CG1 3.42Å; L242-I246 PolarHBondContact O-N 3.01Å; A243-I246 PolarHBondContact O-N 2.9Å; F244-I246 VanDerWaalsContact C-N 3.33Å; F244-I246 PolarHBondContact O-N 2.84Å; I246-F248 VanDerWaalsContact C-N 3.32Å; I246-F248 PolarHBondContact O-N 3.49Å; I246-H249 PolarHBondContact O-N 2.99Å; I246-H249 VanDerWaalsContact O-N 3.13Å; I246-L250 HydrophobicContact CG2-CD1 3.82Å; I246-L250 HydrophobicContact CG2-CG 4.23Å; I246-L250 VanDerWaalsContact O-CG 3.31Å; I246-L250 WeakPolarHBondContact O-CG 3.33Å; I246-L250 PolarHBondContact O-N 2.85Å
247	L	96.9	Very high	88.8	Confident	72 Å²	72	52.3 Å²	52.3	38%	0.377	28%	0.276	S	S	.	.	H	α-helix	trans	-60.1	-40.3	177.2	-69.1	174.3	0	0	0	112.4	F45 A243 F244 L250 G251	F45-L247 HydrophobicContact CD2-CB 3.82Å; F45-L247 HydrophobicContact CE2-CB 4.28Å; F45-L247 HydrophobicContact CE2-CD1 4.43Å; A243-L247 WeakPolarHBondContact O-CG 3.19Å; A243-L247 PolarHBondContact O-N 3.47Å; F244-L247 PolarHBondContact O-N 3.17Å; L247-L250 PolarHBondContact O-N 3.19Å; L247-G251 PolarHBondContact O-N 3.32Å
248	F	96.9	Very high	86.4	Confident	1 Å²	1	57.4 Å²	57.4	0%	0.004	31%	0.307	C	S	.	.	H	α-helix	trans	-59	-49.7	171.8	164.7	-98.3	0	0	0	111.4	A42 F45 G46 H117 H173 L176 F244 S245 I246 L250 G251 I252	A42-F248 WeakPolarHBondContact O-CD2 3.19Å; F45-F248 HydrophobicContact CB-CB 4.11Å; G46-F248 VanDerWaalsContact CA-CG 3.43Å; H117-F248 HydrophobicContact CB-CE1 4.42Å; H117-F248 AromaticContact CD2-CE1 3.86Å; H117-F248 AromaticContact CE1-CD1 3.57Å; H117-F248 AromaticContact CE1-CE1 3.65Å; H117-F248 AromaticContact CG-CE1 3.72Å; H117-F248 AromaticContact ND1-CD1 3.79Å; H117-F248 AromaticContact ND1-CE1 3.57Å; H117-F248 AromaticContact NE2-CE1 3.8Å; H173-F248 AromaticContact CD2-CE2 3.87Å; L176-F248 HydrophobicContact CD2-CE2 3.95Å; L176-F248 HydrophobicContact CD2-CZ 3.61Å; F244-F248 PolarHBondContact O-N 3.37Å; S245-F248 WeakPolarHBondContact O-CB 3.41Å; S245-F248 PolarHBondContact O-N 2.92Å; I246-F248 VanDerWaalsContact C-N 3.32Å; I246-F248 PolarHBondContact O-N 3.49Å; F248-L250 VanDerWaalsContact C-N 3.28Å; F248-L250 PolarHBondContact O-N 2.88Å; F248-G251 PolarHBondContact O-N 3.37Å; F248-I252 HydrophobicContact CD2-CG1 4.01Å; F248-I252 HydrophobicContact CE2-CB 4.47Å; F248-I252 HydrophobicContact CE2-CG1 3.97Å; F248-I252 PolarHBondContact O-N 3.33Å
249	H	94.9	Very high	83.9	Confident	17 Å²	17	61 Å²	61	8%	0.079	33%	0.332	C	S	.	.	H	α-helix	trans	-65.7	-29.3	-178.5	-79.7	-70	0	0	0	113.3	Y110 K114 H117 S245 I246	Y110-H249 AromaticContact CE1-ND1 3.7Å; Y110-H249 AromaticContact CZ-ND1 3.59Å; Y110-H249 WeakPolarHBondContact OH-CB 3.28Å; Y110-H249 PolarHBondContact OH-ND1 3.12Å; K114-H249 PolarHBondContact NZ-O 3.5Å; K114-H249 PolarHBondContact O-CE1 3.48Å; H117-H249 AromaticContact CE1-NE2 3.79Å; H117-H249 AromaticContact ND1-CD2 3.97Å; H117-H249 AromaticContact ND1-CE1 3.48Å; H117-H249 PolarHBondContact ND1-CE1 3.09Å; H117-H249 AromaticContact ND1-NE2 2.98Å; H117-H249 PolarHBondContact ND1-NE2 3.32Å; S245-H249 WeakPolarHBondContact O-CB 3.48Å; S245-H249 PolarHBondContact O-CD2 2.93Å; S245-H249 PolarHBondContact O-N 3.11Å; I246-H249 PolarHBondContact O-N 2.99Å; I246-H249 VanDerWaalsContact O-N 3.13Å
250	L	93.3	Very high	81.5	Confident	132 Å²	132	61.5 Å²	61.5	69%	0.691	33%	0.333	S	S	*	.	H	α-helix	trans	-80.9	-38.4	173.8	-66.9	176	0	0	0	112.8	I246 L247 F248	I246-L250 HydrophobicContact CG2-CD1 3.82Å; I246-L250 HydrophobicContact CG2-CG 4.23Å; I246-L250 VanDerWaalsContact O-CG 3.31Å; I246-L250 WeakPolarHBondContact O-CG 3.33Å; I246-L250 PolarHBondContact O-N 2.85Å; L247-L250 PolarHBondContact O-N 3.19Å; F248-L250 VanDerWaalsContact C-N 3.28Å; F248-L250 PolarHBondContact O-N 2.88Å
251	G	90.3	Very high	78.8	Confident	10 Å²	10	65.1 Å²	65.1	10%	0.103	35%	0.345	C	S	.	.	H	α-helix	trans	-81.4	-26.9	-174	0	0	0	0	0	114.4	L247 F248	L247-G251 PolarHBondContact O-N 3.32Å; F248-G251 PolarHBondContact O-N 3.37Å
252	I	89.2	Confident	76.2	Confident	1 Å²	1	69.1 Å²	69.1	1%	0.005	37%	0.365	C	S	.	.			trans	-102.7	126.7	177.1	-60.8	-62	0	0	0	110.8	R39 A42 F43 K114 L176 L180 F248	R39-I252 HydrophobicContact CB-CD1 4.35Å; R39-I252 VanDerWaalsContact O-CD1 3.28Å; R39-I252 WeakPolarHBondContact O-CD1 3.43Å; A42-I252 HydrophobicContact CB-CD1 4.27Å; A42-I252 HydrophobicContact CB-CG1 4.35Å; F43-I252 HydrophobicContact CB-CD1 4.01Å; K114-I252 PolarHBondContact NZ-O 2.9Å; L176-I252 HydrophobicContact CD2-CG2 4.03Å; L180-I252 HydrophobicContact CD1-CD1 4.32Å; L180-I252 HydrophobicContact CD1-CG2 4.45Å; L180-I252 HydrophobicContact CD2-CG2 3.97Å; F248-I252 HydrophobicContact CD2-CG1 4.01Å; F248-I252 HydrophobicContact CE2-CB 4.47Å; F248-I252 HydrophobicContact CE2-CG1 3.97Å; F248-I252 PolarHBondContact O-N 3.33Å
253	R	82.1	Confident	73.5	Confident	193 Å²	193	74.5 Å²	74.5	73%	0.728	38%	0.382	S	S	*	.			trans	-105.6	126.7	164	-68.8	-175.6	-179.7	179.1	-0.5	108.3	V255	R253-V255 PolarHBondContact O-N 2.75Å
254	E	73.4	Confident	70.9	Confident	42 Å²	42	77.2 Å²	77.2	20%	0.196	39%	0.389	C	S	.	.			trans	-76.4	108.1	172	-162.8	173.3	135.9	0	0	106.8	G111 R112 R113 K114 L176	G111-E254 WeakPolarHBondContact CA-OE1 2.97Å; G111-E254 WeakPolarHBondContact CA-OE2 3.43Å; R112-E254 PolarHBondContact N-OE1 3.48Å; R112-E254 PolarHBondContact N-OE2 3.45Å; R113-E254 PolarHBondContact N-OE1 2.99Å; R113-E254 PolarHBondContact N-OE2 3.49Å; K114-E254 HydrophobicContact CD-CB 4.11Å; K114-E254 HydrophobicContact CG-CB 4.41Å; K114-E254 PolarHBondContact N-OE2 3.18Å; L176-E254 HydrophobicContact CD1-CG 4.27Å
255	V	64	Low	67.9	Low	103 Å²	103	80.6 Å²	80.6	62%	0.624	41%	0.405	S	S	*	.	P	Polyproline II helix	trans	-81.6	123.4	172.1	-175.9	0	0	0	0	105.9	R253 P257	R253-V255 PolarHBondContact O-N 2.75Å; V255-P257 WeakPolarHBondContact O-CD 3.21Å
256	R	54.1	Low	65.4	Low	150 Å²	150	87.6 Å²	87.6	57%	0.566	44%	0.436	S	S	*	.	P	Polyproline II helix	trans	-58.4	125.8	173.7	-69.2	-170.2	-172.8	173.6	11	108.2	I108 V258	I108-R256 PolarHBondContact O-NE 2.99Å; I108-R256 PolarHBondContact O-NH2 2.87Å; R256-V258 PolarHBondContact O-N 3.31Å
257	P	49.6	Very low	62.8	Low	64 Å²	64	89.1 Å²	89.1	42%	0.416	45%	0.445	S	S	.	.	P	Polyproline II helix	trans	-61.9	130.8	170.1	20.8	-24.8	0	0	0	108.2	V255 S259 A260	V255-P257 WeakPolarHBondContact O-CD 3.21Å; P257-S259 PolarHBondContact O-N 3.34Å; P257-A260 WeakPolarHBondContact O-CB 3.22Å; P257-A260 PolarHBondContact O-N 2.91Å
258	V	47	Very low	59.9	Low	107 Å²	107	91.8 Å²	91.8	65%	0.648	46%	0.46	S	S	*	.	H	α-helix	trans	-50.9	-25.7	176	175.6	0	0	0	0	111.4	R256 A260 F261 I262	R256-V258 PolarHBondContact O-N 3.31Å; V258-A260 VanDerWaalsContact C-N 3.29Å; V258-A260 PolarHBondContact O-N 2.73Å; V258-F261 WeakPolarHBondContact O-CB 3.31Å; V258-F261 PolarHBondContact O-N 2.89Å; V258-I262 HydrophobicContact CG1-CD1 3.9Å; V258-I262 HydrophobicContact CG1-CG1 4.14Å; V258-I262 WeakPolarHBondContact O-CG1 3.36Å; V258-I262 PolarHBondContact O-N 3.2Å
259	S	45.6	Very low	57	Low	81 Å²	81	97.6 Å²	97.6	57%	0.566	49%	0.491	S	S	*	.	H	α-helix	trans	-61.6	-29.8	174.3	63.9	0	0	0	0	114.4	P257 R263	P257-S259 PolarHBondContact O-N 3.34Å; S259-R263 WeakPolarHBondContact O-CB 3.23Å; S259-R263 PolarHBondContact O-N 3.11Å
260	A	47.2	Very low	54.3	Low	52 Å²	52	105 Å²	105	43%	0.43	53%	0.531	S	S	.	.	H	α-helix	trans	-71.8	-36.8	172.8	0	0	0	0	0	110.9	P257 V258 R263 D264	P257-A260 WeakPolarHBondContact O-CB 3.22Å; P257-A260 PolarHBondContact O-N 2.91Å; V258-A260 VanDerWaalsContact C-N 3.29Å; V258-A260 PolarHBondContact O-N 2.73Å; A260-R263 PolarHBondContact O-N 2.98Å; A260-D264 VanDerWaalsContact O-CB 3.24Å; A260-D264 WeakPolarHBondContact O-CB 3.25Å; A260-D264 PolarHBondContact O-N 3.5Å
261	F	42.1	Very low	51.6	Low	126 Å²	126	100.9 Å²	100.9	55%	0.553	52%	0.521	S	S	*	.	H	α-helix	trans	-67.2	-41.5	174.9	-159.9	-93.5	0	0	0	111.5	V258 H265	V258-F261 WeakPolarHBondContact O-CB 3.31Å; V258-F261 PolarHBondContact O-N 2.89Å; F261-H265 AromaticContact CD1-CE1 3.58Å; F261-H265 AromaticContact CD1-ND1 3.56Å; F261-H265 AromaticContact CE1-CE1 3.07Å; F261-H265 WeakPolarHBondContact CE1-CE1 3.2Å; F261-H265 AromaticContact CE1-ND1 3.52Å; F261-H265 AromaticContact CE1-NE2 3.42Å; F261-H265 WeakPolarHBondContact CE1-NE2 3.32Å; F261-H265 AromaticContact CE2-CE1 3.63Å; F261-H265 AromaticContact CZ-CE1 3.1Å; F261-H265 WeakPolarHBondContact CZ-CE1 3.31Å; F261-H265 AromaticContact CZ-ND1 3.94Å; F261-H265 AromaticContact CZ-NE2 3.56Å; F261-H265 WeakPolarHBondContact O-CB 3.31Å; F261-H265 PolarHBondContact O-N 3.45Å; F261-H265 PolarHBondContact O-ND1 3.33Å
262	I	43.7	Very low	49	Very low	84 Å²	84	107.1 Å²	107.1	43%	0.431	56%	0.557	S	S	.	*	H	α-helix	trans	-63.5	-45.8	175.7	-70.2	175.2	0	0	0	111	V258 H265 F266	V258-I262 HydrophobicContact CG1-CD1 3.9Å; V258-I262 HydrophobicContact CG1-CG1 4.14Å; V258-I262 WeakPolarHBondContact O-CG1 3.36Å; V258-I262 PolarHBondContact O-N 3.2Å; I262-H265 PolarHBondContact O-N 2.98Å; I262-F266 HydrophobicContact CG2-CD2 3.41Å; I262-F266 VanDerWaalsContact CG2-CD2 3.41Å; I262-F266 HydrophobicContact CG2-CE2 3.42Å; I262-F266 VanDerWaalsContact CG2-CE2 3.42Å; I262-F266 WeakPolarHBondContact O-CD2 3.35Å; I262-F266 PolarHBondContact O-N 3.43Å
263	R	42.6	Very low	46.5	Very low	162 Å²	162	113 Å²	113	61%	0.611	59%	0.592	S	S	*	*	H	α-helix	trans	-66.2	-40.3	179.1	-153.6	177.2	92.6	-167.1	-0.7	112.4	S259 A260 H265 F266 D267	S259-R263 WeakPolarHBondContact O-CB 3.23Å; S259-R263 PolarHBondContact O-N 3.11Å; A260-R263 PolarHBondContact O-N 2.98Å; R263-H265 VanDerWaalsContact C-N 3.3Å; R263-H265 PolarHBondContact O-N 2.9Å; R263-F266 PolarHBondContact O-N 3.16Å; R263-D267 WeakPolarHBondContact O-CB 3.31Å; R263-D267 PolarHBondContact O-N 2.94Å
264	D	42.2	Very low	44.1	Very low	105 Å²	105	110.4 Å²	110.4	56%	0.561	59%	0.593	S	S	*	*	H	α-helix	trans	-72.1	-23.2	178.7	-147.4	30.2	0	0	0	112.7	A260 N268	A260-D264 VanDerWaalsContact O-CB 3.24Å; A260-D264 WeakPolarHBondContact O-CB 3.25Å; A260-D264 PolarHBondContact O-N 3.5Å; D264-N268 PolarHBondContact O-ND2 3.48Å
265	H	36.8	Very low	42.4	Very low	104 Å²	104	115 Å²	115	48%	0.481	62%	0.618	S	S	.	*	H	α-helix	trans	-82.5	-37.6	171.5	-80.2	60.9	0	0	0	112.5	F261 I262 R263 N268 D269	F261-H265 AromaticContact CD1-CE1 3.58Å; F261-H265 AromaticContact CD1-ND1 3.56Å; F261-H265 AromaticContact CE1-CE1 3.07Å; F261-H265 WeakPolarHBondContact CE1-CE1 3.2Å; F261-H265 AromaticContact CE1-ND1 3.52Å; F261-H265 AromaticContact CE1-NE2 3.42Å; F261-H265 WeakPolarHBondContact CE1-NE2 3.32Å; F261-H265 AromaticContact CE2-CE1 3.63Å; F261-H265 AromaticContact CZ-CE1 3.1Å; F261-H265 WeakPolarHBondContact CZ-CE1 3.31Å; F261-H265 AromaticContact CZ-ND1 3.94Å; F261-H265 AromaticContact CZ-NE2 3.56Å; F261-H265 WeakPolarHBondContact O-CB 3.31Å; F261-H265 PolarHBondContact O-N 3.45Å; F261-H265 PolarHBondContact O-ND1 3.33Å; I262-H265 PolarHBondContact O-N 2.98Å; R263-H265 VanDerWaalsContact C-N 3.3Å; R263-H265 PolarHBondContact O-N 2.9Å; H265-N268 PolarHBondContact O-N 3.02Å; H265-D269 PolarHBondContact O-N 2.89Å
266	F	43.9	Very low	41.1	Very low	149 Å²	149	118.9 Å²	118.9	65%	0.654	63%	0.63	S	S	*	*	H	α-helix	trans	-75.5	-26.3	176.2	-78.4	-63.3	0	0	0	113.5	I262 R263 N268	I262-F266 HydrophobicContact CG2-CD2 3.41Å; I262-F266 VanDerWaalsContact CG2-CD2 3.41Å; I262-F266 HydrophobicContact CG2-CE2 3.42Å; I262-F266 VanDerWaalsContact CG2-CE2 3.42Å; I262-F266 WeakPolarHBondContact O-CD2 3.35Å; I262-F266 PolarHBondContact O-N 3.43Å; R263-F266 PolarHBondContact O-N 3.16Å; F266-N268 VanDerWaalsContact C-N 3.31Å
267	D	42.1	Very low	40.2	Very low	116 Å²	116	117.3 Å²	117.3	62%	0.62	64%	0.642	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.2	-15.2	174.5	-78.1	-27.3	0	0	0	112.8	R263	R263-D267 WeakPolarHBondContact O-CB 3.31Å; R263-D267 PolarHBondContact O-N 2.94Å
268	N	37.2	Very low	39.5	Very low	129 Å²	129	119.4 Å²	119.4	69%	0.69	65%	0.654	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.7	-8.4	178.6	-79.3	-51.2	0	0	0	114.4	D264 H265 F266	D264-N268 PolarHBondContact O-ND2 3.48Å; H265-N268 PolarHBondContact O-N 3.02Å; F266-N268 VanDerWaalsContact C-N 3.31Å
269	D	34.7	Very low	39.1	Very low	122 Å²	122	117.8 Å²	117.8	65%	0.652	64%	0.644	S	S	*	*			trans	-100.5	107.6	174.3	-143.4	7.1	0	0	0	107.3	H265 G271	H265-D269 PolarHBondContact O-N 2.89Å; D269-G271 PolarHBondContact O-N 3.26Å
270	D	39.7	Very low	38.6	Very low	172 Å²	172	121.5 Å²	121.5	92%	0.92	66%	0.657	S	S	*	*			trans	-65.8	41	171	-80.2	-39.5	0	0	0	111.4	V272	D270-V272 PolarHBondContact O-N 3.2Å
271	G	36.3	Very low	38.1	Very low	46 Å²	46	129.7 Å²	129.7	47%	0.474	68%	0.677	S	S	.	*			trans	-90.4	99.9	179.8	0	0	0	0	0	110.2	D269 V273	D269-G271 PolarHBondContact O-N 3.26Å; G271-V273 VanDerWaalsContact C-N 3.34Å; G271-V273 PolarHBondContact O-N 3.35Å
272	V	36.5	Very low	37.8	Very low	142 Å²	142	132.2 Å²	132.2	86%	0.861	69%	0.688	S	S	*	*			trans	-53.9	96.4	162.5	180	0	0	0	0	108.3	D270	D270-V272 PolarHBondContact O-N 3.2Å
273	V	35.7	Very low	37.9	Very low	123 Å²	123	131.2 Å²	131.2	75%	0.745	69%	0.692	S	S	*	*			trans	-123	129.7	171.9	-178.1	0	0	0	0	108.8	G271	G271-V273 VanDerWaalsContact C-N 3.34Å; G271-V273 PolarHBondContact O-N 3.35Å
274	D	31.6	Very low	38.3	Very low	139 Å²	139	125.5 Å²	125.5	74%	0.743	68%	0.68	S	S	*	*			trans	-53.2	136.2	-164.2	-66.2	-55.9	0	0	0	115.5	E276	D274-E276 PolarHBondContact O-N 3.45Å
275	N	37.5	Very low	39	Very low	138 Å²	138	125.4 Å²	125.4	74%	0.738	68%	0.679	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.8	23.5	-171.4	-105.6	-25.2	0	0	0	115.7
276	E	36.1	Very low	40.3	Very low	185 Å²	185	121.2 Å²	121.2	86%	0.864	66%	0.661	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.7	-10	-167.7	-77.8	-168	152.7	0	0	116.8	D274	D274-E276 PolarHBondContact O-N 3.45Å
277	S	35.7	Very low	41.7	Very low	118 Å²	118	117 Å²	117	83%	0.825	65%	0.648	S	S	*	*	S	Bend	trans	-114.4	10	-177.1	66.6	0	0	0	0	116.7
278	T	35.3	Very low	43.4	Very low	108 Å²	108	117.2 Å²	117.2	66%	0.663	64%	0.64	S	S	*	*	S	Bend	trans	-111.5	6.1	176.7	55.4	0	0	0	0	114.7
279	V	39.2	Very low	45.4	Very low	72 Å²	72	119.1 Å²	119.1	44%	0.436	64%	0.637	S	S	.	*	G	3₁₀ helix	trans	-82.9	-16.4	-168.3	-176.6	0	0	0	0	115	R281 R502	V279-R281 PolarHBondContact O-N 2.98Å; V279-R502 VanDerWaalsContact CG1-NH2 3.29Å
280	D	34.9	Very low	47.6	Very low	159 Å²	159	115.8 Å²	115.8	85%	0.85	62%	0.617	S	S	*	*	G	3₁₀ helix	trans	-92.2	15.8	-173.5	-82.7	-14.6	0	0	0	116.5
281	R	37	Very low	49.7	Very low	225 Å²	225	107.7 Å²	107.7	85%	0.849	57%	0.574	S	S	*	*	G	3₁₀ helix	trans	-129.7	15.7	176.6	-140.5	179.2	168.8	-171.4	-4.4	116.7	V279 A283	V279-R281 PolarHBondContact O-N 2.98Å; R281-A283 PolarHBondContact O-N 3.39Å
282	K	35	Very low	52	Low	179 Å²	179	108.9 Å²	108.9	78%	0.778	57%	0.569	S	S	*	*			trans	-70.5	71.5	155.9	-70	-176.6	-177	175.3	0	108.2	A284	K282-A284 PolarHBondContact O-N 3.46Å
283	A	46	Very low	54.3	Low	63 Å²	63	108.6 Å²	108.6	52%	0.521	56%	0.557	S	S	.	*			trans	-50.5	114.4	154.7	0	0	0	0	0	104.6	R281 N285	R281-A283 PolarHBondContact O-N 3.39Å; A283-N285 PolarHBondContact O-N 2.94Å; A283-N285 PolarHBondContact O-OD1 3.3Å
284	A	51.2	Low	56.6	Low	42 Å²	42	103.6 Å²	103.6	35%	0.347	53%	0.525	S	S	.	.			trans	-35.9	111.8	-174.2	0	0	0	0	0	109.7	K282 V286 I497	K282-A284 PolarHBondContact O-N 3.46Å; A284-V286 VanDerWaalsContact C-N 3.33Å; A284-V286 WeakPolarHBondContact O-CG2 3.49Å; A284-V286 PolarHBondContact O-N 3.02Å; A284-I497 HydrophobicContact CB-CB 4.44Å; A284-I497 HydrophobicContact CB-CG1 4.23Å; A284-I497 HydrophobicContact CB-CG2 3.44Å; A284-I497 VanDerWaalsContact CB-CG2 3.44Å
285	N	56.7	Low	59.3	Low	103 Å²	103	101.9 Å²	101.9	55%	0.551	52%	0.516	S	S	*	.			trans	-56.3	100.4	-169.9	-74.6	10.5	0	0	0	107.8	A283 T287	A283-N285 PolarHBondContact O-N 2.94Å; A283-N285 PolarHBondContact O-OD1 3.3Å; N285-T287 PolarHBondContact O-N 3.39Å; N285-T287 PolarHBondContact O-OG1 3.37Å
286	V	63.6	Low	61.8	Low	15 Å²	15	95.7 Å²	95.7	9%	0.091	48%	0.483	C	S	.	.			trans	-70	91.3	179.1	173.9	0	0	0	0	106.1	A284 H290 W291 S421 L494 I497	A284-V286 VanDerWaalsContact C-N 3.33Å; A284-V286 WeakPolarHBondContact O-CG2 3.49Å; A284-V286 PolarHBondContact O-N 3.02Å; V286-H290 HydrophobicContact CG1-CB 4.06Å; V286-W291 HydrophobicContact CG1-CZ2 4.33Å; V286-S421 WeakPolarHBondContact CB-OG 3.4Å; V286-S421 WeakPolarHBondContact CG1-OG 3.35Å; V286-S421 WeakPolarHBondContact O-CB 3.43Å; V286-S421 PolarHBondContact O-OG 2.98Å; V286-L494 HydrophobicContact CB-CD1 4.2Å; V286-L494 HydrophobicContact CG1-CD1 3.22Å; V286-L494 HydrophobicContact CG2-CD1 3.84Å; V286-I497 HydrophobicContact CG2-CD1 4.27Å
287	T	73	Confident	64.3	Low	62 Å²	62	87.4 Å²	87.4	38%	0.38	44%	0.444	S	S	.	.			trans	-63.4	150.1	174.4	-48.9	0	0	0	0	110.2	N285 R289 H290	N285-T287 PolarHBondContact O-N 3.39Å; N285-T287 PolarHBondContact O-OG1 3.37Å; T287-R289 PolarHBondContact O-N 2.86Å; T287-H290 PolarHBondContact N-ND1 3.2Å; T287-H290 WeakPolarHBondContact O-CB 3.28Å; T287-H290 PolarHBondContact O-N 3.36Å; T287-H290 PolarHBondContact O-ND1 3.45Å; T287-H290 VanDerWaalsContact O-ND1 3.16Å
288	W	77.9	Confident	67	Low	120 Å²	120	87.3 Å²	87.3	46%	0.455	43%	0.426	S	S	.	.	H	α-helix	trans	-47.3	-32.7	176.7	65.3	-89.7	0	0	0	114.2	H290 W291 L292 F424	W288-H290 VanDerWaalsContact C-N 3.27Å; W288-H290 PolarHBondContact O-N 3.49Å; W288-W291 WeakPolarHBondContact O-CB 3.38Å; W288-W291 PolarHBondContact O-N 3.12Å; W288-L292 HydrophobicContact CE3-CD1 3.75Å; W288-L292 HydrophobicContact CE3-CG 4.44Å; W288-L292 HydrophobicContact CZ3-CD1 3.49Å; W288-L292 VanDerWaalsContact CZ3-CD1 3.49Å; W288-F424 HydrophobicContact CB-CD1 4Å; W288-F424 HydrophobicContact CB-CD2 3.81Å; W288-F424 HydrophobicContact CB-CE1 4.12Å; W288-F424 HydrophobicContact CB-CE2 3.94Å; W288-F424 HydrophobicContact CB-CG 3.84Å; W288-F424 HydrophobicContact CB-CZ 4.09Å; W288-F424 HydrophobicContact CE3-CE2 4.46Å; W288-F424 HydrophobicContact CE3-CZ 4.33Å
289	R	79.9	Confident	69.8	Low	168 Å²	168	83 Å²	83	63%	0.634	40%	0.4	S	S	*	.	H	α-helix	trans	-60.9	-31.9	176.9	-65.6	-174	178.5	179.4	-0	113.5	T287 W291 L292	T287-R289 PolarHBondContact O-N 2.86Å; R289-W291 VanDerWaalsContact C-N 3.32Å; R289-L292 PolarHBondContact O-N 2.99Å
290	H	82.1	Confident	72.4	Confident	52 Å²	52	79.7 Å²	79.7	24%	0.241	38%	0.379	C	S	.	.	H	α-helix	trans	-68.9	-32.6	178.5	-59.3	105.2	0	0	0	111.9	V286 T287 W288 L292 K293 N294 L494	V286-H290 HydrophobicContact CG1-CB 4.06Å; T287-H290 PolarHBondContact N-ND1 3.2Å; T287-H290 WeakPolarHBondContact O-CB 3.28Å; T287-H290 PolarHBondContact O-N 3.36Å; T287-H290 PolarHBondContact O-ND1 3.45Å; T287-H290 VanDerWaalsContact O-ND1 3.16Å; W288-H290 VanDerWaalsContact C-N 3.27Å; W288-H290 PolarHBondContact O-N 3.49Å; H290-L292 VanDerWaalsContact C-N 3.31Å; H290-L292 PolarHBondContact O-N 3.32Å; H290-K293 PolarHBondContact O-N 3.34Å; H290-N294 PolarHBondContact O-N 3.39Å; H290-L494 HydrophobicContact CB-CD1 4.05Å
291	W	82.6	Confident	75.2	Confident	2 Å²	2	72.7 Å²	72.7	1%	0.008	34%	0.342	C	S	.	.	H	α-helix	trans	-64	-37.9	174.7	-69.5	113.4	0	0	0	112.2	V286 W288 R289 K293 N294 F297 L414 S421 F424 V425 L494	V286-W291 HydrophobicContact CG1-CZ2 4.33Å; W288-W291 WeakPolarHBondContact O-CB 3.38Å; W288-W291 PolarHBondContact O-N 3.12Å; R289-W291 VanDerWaalsContact C-N 3.32Å; W291-K293 PolarHBondContact O-N 3.08Å; W291-N294 PolarHBondContact O-N 2.9Å; W291-F297 HydrophobicContact CB-CD2 4.28Å; W291-F297 HydrophobicContact CB-CG 4.31Å; W291-F297 HydrophobicContact CE3-CB 4.27Å; W291-F297 HydrophobicContact CE3-CD2 4.22Å; W291-F297 WeakPolarHBondContact O-CD1 3.4Å; W291-L414 HydrophobicContact CH2-CG 4.48Å; W291-L414 HydrophobicContact CZ3-CD1 3.96Å; W291-L414 HydrophobicContact CZ3-CD2 4.4Å; W291-L414 HydrophobicContact CZ3-CG 3.86Å; W291-S421 VanDerWaalsContact NE1-CB 3.28Å; W291-S421 PolarHBondContact NE1-OG 2.92Å; W291-F424 HydrophobicContact CB-CD1 4.17Å; W291-F424 HydrophobicContact CB-CE1 3.94Å; W291-F424 AromaticContact CD1-CD1 3.8Å; W291-F424 HydrophobicContact CG-CD1 4.2Å; W291-F424 HydrophobicContact CG-CE1 4.46Å; W291-V425 HydrophobicContact CD2-CG2 3.49Å; W291-V425 VanDerWaalsContact CD2-CG2 3.49Å; W291-V425 VanDerWaalsContact CE2-CG2 3.45Å; W291-V425 HydrophobicContact CE3-CG2 3.91Å; W291-V425 HydrophobicContact CG-CG2 3.88Å; W291-V425 HydrophobicContact CH2-CG2 4.25Å; W291-V425 HydrophobicContact CZ2-CG2 3.84Å; W291-V425 HydrophobicContact CZ3-CG2 4.27Å; W291-L494 HydrophobicContact CE3-CD2 4.45Å
292	L	84.6	Confident	77.9	Confident	71 Å²	71	65.7 Å²	65.7	37%	0.372	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68	-13.6	176.9	-59.4	-177.8	0	0	0	113.6	W288 R289 H290 F297 Y298 F424	W288-L292 HydrophobicContact CE3-CD1 3.75Å; W288-L292 HydrophobicContact CE3-CG 4.44Å; W288-L292 HydrophobicContact CZ3-CD1 3.49Å; W288-L292 VanDerWaalsContact CZ3-CD1 3.49Å; R289-L292 PolarHBondContact O-N 2.99Å; H290-L292 VanDerWaalsContact C-N 3.31Å; H290-L292 PolarHBondContact O-N 3.32Å; L292-F297 HydrophobicContact CD2-CE1 4.19Å; L292-Y298 VanDerWaalsContact O-CE2 3.26Å; L292-Y298 WeakPolarHBondContact O-CE2 3.32Å; L292-Y298 PolarHBondContact O-OH 3.16Å; L292-F424 HydrophobicContact CD2-CZ 4.3Å
293	K	85.3	Confident	80.8	Confident	137 Å²	137	57.2 Å²	57.2	60%	0.596	29%	0.285	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.7	-15.7	171.9	-67.9	178.7	169.4	-175.7	0	112.7	H290 W291 N295 D496	H290-K293 PolarHBondContact O-N 3.34Å; W291-K293 PolarHBondContact O-N 3.08Å; K293-N295 PolarHBondContact O-N 2.99Å; K293-D496 WeakPolarHBondContact CD-OD2 3.1Å; K293-D496 IonicContact NZ-OD2 2.93Å; K293-D496 PolarHBondContact NZ-OD2 3.46Å
294	N	84.6	Confident	83.1	Confident	17 Å²	17	54.6 Å²	54.6	9%	0.091	26%	0.261	C	S	.	.			trans	-84.5	116.7	-172.9	-172.7	-10.3	0	0	0	111.5	H290 W291 Q296 F297 Y298 L494	H290-N294 PolarHBondContact O-N 3.39Å; W291-N294 PolarHBondContact O-N 2.9Å; N294-Q296 VanDerWaalsContact C-N 3.29Å; N294-Q296 PolarHBondContact O-N 3.19Å; N294-Q296 WeakPolarHBondContact OD1-CB 3.46Å; N294-Q296 PolarHBondContact OD1-N 2.84Å; N294-F297 HydrophobicContact CB-CB 4Å; N294-F297 VanDerWaalsContact O-CB 3.31Å; N294-F297 WeakPolarHBondContact O-CB 3.45Å; N294-F297 PolarHBondContact O-N 3.27Å; N294-F297 VanDerWaalsContact O-N 3.11Å; N294-Y298 VanDerWaalsContact O-CD2 3.29Å; N294-Y298 WeakPolarHBondContact O-CD2 2.94Å; N294-L494 HydrophobicContact CB-CD2 3.56Å; N294-L494 WeakPolarHBondContact ND2-CD2 3.41Å
295	N	87.2	Confident	85.2	Confident	103 Å²	103	53.8 Å²	53.8	55%	0.551	25%	0.251	S	S	*	.	H	α-helix	trans	-61.2	-35	176.2	-168.4	32.2	0	0	0	113.1	K293 F297 Y298 L299	K293-N295 PolarHBondContact O-N 2.99Å; N295-F297 PolarHBondContact O-N 2.71Å; N295-Y298 PolarHBondContact O-N 3.2Å; N295-L299 PolarHBondContact O-N 2.92Å; N295-L299 VanDerWaalsContact O-N 3.16Å
296	Q	89.5	Confident	87.2	Confident	9 Å²	9	49.4 Å²	49.4	4%	0.042	23%	0.227	C	C	.	.	H	α-helix	trans	-63.9	-33.3	176.5	-67.9	-166.9	-14	0	0	112.2	N294 Y298 L299 I300 L414 K489	N294-Q296 VanDerWaalsContact C-N 3.29Å; N294-Q296 PolarHBondContact O-N 3.19Å; N294-Q296 WeakPolarHBondContact OD1-CB 3.46Å; N294-Q296 PolarHBondContact OD1-N 2.84Å; Q296-Y298 VanDerWaalsContact C-N 3.33Å; Q296-Y298 PolarHBondContact O-N 3.39Å; Q296-L299 PolarHBondContact O-N 3.18Å; Q296-I300 WeakPolarHBondContact O-CB 3.48Å; Q296-I300 WeakPolarHBondContact O-CG1 3.42Å; Q296-I300 PolarHBondContact O-N 3.19Å; Q296-L414 HydrophobicContact CB-CD1 3.84Å; Q296-K489 PolarHBondContact NE2-O 3.49Å
297	F	90.2	Very high	88.8	Confident	10 Å²	10	48.8 Å²	48.8	4%	0.044	22%	0.224	C	C	.	.	H	α-helix	trans	-60.5	-45.1	176.8	168.6	-100.8	0	0	0	110.9	W291 L292 N294 N295 S301 L414 F424 V425 A428	W291-F297 HydrophobicContact CB-CD2 4.28Å; W291-F297 HydrophobicContact CB-CG 4.31Å; W291-F297 HydrophobicContact CE3-CB 4.27Å; W291-F297 HydrophobicContact CE3-CD2 4.22Å; W291-F297 WeakPolarHBondContact O-CD1 3.4Å; L292-F297 HydrophobicContact CD2-CE1 4.19Å; N294-F297 HydrophobicContact CB-CB 4Å; N294-F297 VanDerWaalsContact O-CB 3.31Å; N294-F297 WeakPolarHBondContact O-CB 3.45Å; N294-F297 PolarHBondContact O-N 3.27Å; N294-F297 VanDerWaalsContact O-N 3.11Å; N295-F297 PolarHBondContact O-N 2.71Å; F297-S301 WeakPolarHBondContact O-CB 3.25Å; F297-S301 PolarHBondContact O-N 3.41Å; F297-S301 PolarHBondContact O-OG 3Å; F297-L414 HydrophobicContact CB-CD2 4.28Å; F297-L414 HydrophobicContact CD2-CD2 4.2Å; F297-F424 HydrophobicContact CZ-CE1 4.37Å; F297-V425 HydrophobicContact CD2-CG1 4.09Å; F297-V425 HydrophobicContact CD2-CG2 4.18Å; F297-V425 HydrophobicContact CE2-CB 4.25Å; F297-V425 HydrophobicContact CE2-CG1 3.94Å; F297-V425 HydrophobicContact CE2-CG2 4.08Å; F297-A428 HydrophobicContact CZ-CB 4.17Å
298	Y	92.2	Very high	89.8	Confident	116 Å²	116	49.1 Å²	49.1	46%	0.455	22%	0.218	S	C	.	.	H	α-helix	trans	-65.9	-46.2	177.3	-67.1	-73.3	0	0	0	112.8	L292 N294 N295 Q296 I300 S301 L302	L292-Y298 VanDerWaalsContact O-CE2 3.26Å; L292-Y298 WeakPolarHBondContact O-CE2 3.32Å; L292-Y298 PolarHBondContact O-OH 3.16Å; N294-Y298 VanDerWaalsContact O-CD2 3.29Å; N294-Y298 WeakPolarHBondContact O-CD2 2.94Å; N295-Y298 PolarHBondContact O-N 3.2Å; Q296-Y298 VanDerWaalsContact C-N 3.33Å; Q296-Y298 PolarHBondContact O-N 3.39Å; Y298-I300 PolarHBondContact O-N 3.4Å; Y298-S301 PolarHBondContact O-N 3.34Å; Y298-L302 VanDerWaalsContact O-CB 3.23Å; Y298-L302 WeakPolarHBondContact O-CB 3.38Å; Y298-L302 PolarHBondContact O-N 2.91Å
299	L	93.5	Very high	90.7	Very high	19 Å²	19	44.2 Å²	44.2	10%	0.099	20%	0.201	C	C	.	.	H	α-helix	trans	-62.5	-45.2	-179.1	-69.7	175	0	0	0	112.4	N295 Q296 F303 L484 L485	N295-L299 PolarHBondContact O-N 2.92Å; N295-L299 VanDerWaalsContact O-N 3.16Å; Q296-L299 PolarHBondContact O-N 3.18Å; L299-F303 WeakPolarHBondContact O-CB 3.5Å; L299-F303 PolarHBondContact O-N 3.39Å; L299-L484 HydrophobicContact CD1-CB 4.31Å; L299-L484 HydrophobicContact CD2-CB 4.22Å; L299-L484 HydrophobicContact CD2-CD1 3.98Å; L299-L485 HydrophobicContact CB-CD1 4.15Å; L299-L485 HydrophobicContact CB-CD2 3.75Å; L299-L485 HydrophobicContact CB-CG 3.89Å; L299-L485 HydrophobicContact CD1-CD2 3.89Å; L299-L485 HydrophobicContact CD1-CG 4.19Å; L299-L485 HydrophobicContact CG-CD2 4.49Å
300	I	93	Very high	91.5	Very high	1 Å²	1	36.3 Å²	36.3	1%	0.005	17%	0.171	C	C	.	.	H	α-helix	trans	-72.7	-38.4	-179.9	-66	172.1	0	0	0	111	Q296 Y298 F303 Y304 L410 L414 M429 L485 V490	Q296-I300 WeakPolarHBondContact O-CB 3.48Å; Q296-I300 WeakPolarHBondContact O-CG1 3.42Å; Q296-I300 PolarHBondContact O-N 3.19Å; Y298-I300 PolarHBondContact O-N 3.4Å; I300-F303 PolarHBondContact O-N 3.42Å; I300-Y304 WeakPolarHBondContact O-CB 3.39Å; I300-Y304 PolarHBondContact O-N 3.09Å; I300-L410 HydrophobicContact CG2-CB 4.32Å; I300-L414 HydrophobicContact CB-CD2 4.2Å; I300-L414 HydrophobicContact CD1-CB 3.79Å; I300-L414 HydrophobicContact CD1-CD1 4.15Å; I300-L414 HydrophobicContact CD1-CD2 4.18Å; I300-L414 HydrophobicContact CD1-CG 4.25Å; I300-L414 HydrophobicContact CG2-CD2 4.3Å; I300-M429 HydrophobicContact CG2-CE 4.04Å; I300-L485 HydrophobicContact CD1-CD2 4.47Å; I300-L485 HydrophobicContact CG1-CD1 3.8Å; I300-L485 HydrophobicContact CG1-CD2 4.01Å; I300-V490 HydrophobicContact CD1-CG1 3.64Å; I300-V490 HydrophobicContact CD1-CG2 4.45Å
301	S	93.3	Very high	92.2	Very high	12 Å²	12	34.3 Å²	34.3	8%	0.084	16%	0.162	C	C	.	.	H	α-helix	trans	-61.4	-47.2	174.6	-61.2	0	0	0	0	110.9	F297 Y298 F303 Y304 M305 M429	F297-S301 WeakPolarHBondContact O-CB 3.25Å; F297-S301 PolarHBondContact O-N 3.41Å; F297-S301 PolarHBondContact O-OG 3Å; Y298-S301 PolarHBondContact O-N 3.34Å; S301-F303 PolarHBondContact O-N 2.77Å; S301-Y304 PolarHBondContact O-N 2.8Å; S301-M305 WeakPolarHBondContact O-CB 3.24Å; S301-M305 WeakPolarHBondContact O-CG 3.46Å; S301-M305 PolarHBondContact O-N 3.15Å; S301-M429 WeakPolarHBondContact OG-CE 3.44Å; S301-M429 WeakPolarHBondContact OG-CG 3.45Å
302	L	95.3	Very high	92.8	Very high	78 Å²	78	35.2 Å²	35.2	41%	0.408	17%	0.167	S	C	.	.	H	α-helix	trans	-63.4	-43.1	178.1	-176.6	59	0	0	0	111.5	Y298 M305 L306 T481	Y298-L302 VanDerWaalsContact O-CB 3.23Å; Y298-L302 WeakPolarHBondContact O-CB 3.38Å; Y298-L302 PolarHBondContact O-N 2.91Å; L302-M305 PolarHBondContact O-N 3.04Å; L302-L306 HydrophobicContact CD1-CD1 3.96Å; L302-L306 HydrophobicContact CD1-CG 4.12Å; L302-L306 HydrophobicContact CG-CD1 3.84Å; L302-L306 HydrophobicContact CG-CG 4.44Å; L302-L306 WeakPolarHBondContact O-CB 3.33Å; L302-L306 WeakPolarHBondContact O-CD1 3.42Å; L302-L306 WeakPolarHBondContact O-CG 3.5Å; L302-L306 PolarHBondContact O-N 3.21Å; L302-T481 HydrophobicContact CB-CG2 4.26Å; L302-T481 HydrophobicContact CD2-CG2 3.62Å; L302-T481 HydrophobicContact CG-CG2 3.87Å
303	F	95.9	Very high	93.4	Very high	1 Å²	1	31.9 Å²	31.9	0%	0.004	15%	0.149	C	C	.	.	H	α-helix	trans	-57.3	-49.7	174.1	-179.2	-104.7	0	0	0	112.1	L299 I300 S301 L306 I307 I370 A407 L410 A478 T481 L482	L299-F303 WeakPolarHBondContact O-CB 3.5Å; L299-F303 PolarHBondContact O-N 3.39Å; I300-F303 PolarHBondContact O-N 3.42Å; S301-F303 PolarHBondContact O-N 2.77Å; F303-L306 PolarHBondContact O-N 3.21Å; F303-I307 HydrophobicContact CD1-CD1 3.72Å; F303-I307 HydrophobicContact CD2-CD1 4.21Å; F303-I307 HydrophobicContact CE1-CD1 3.22Å; F303-I307 HydrophobicContact CE2-CD1 3.77Å; F303-I307 HydrophobicContact CG-CD1 4.2Å; F303-I307 HydrophobicContact CZ-CD1 3.25Å; F303-I307 HydrophobicContact CZ-CG1 4.46Å; F303-I307 WeakPolarHBondContact O-CG1 3.47Å; F303-I307 PolarHBondContact O-N 3.26Å; F303-I307 VanDerWaalsContact O-N 3.12Å; F303-I370 HydrophobicContact CE2-CD1 4.27Å; F303-A407 HydrophobicContact CD1-CB 4.33Å; F303-A407 HydrophobicContact CE1-CB 4.15Å; F303-L410 HydrophobicContact CD1-CD1 4.04Å; F303-L410 HydrophobicContact CE1-CD1 3.7Å; F303-L410 HydrophobicContact CZ-CD1 4.47Å; F303-A478 HydrophobicContact CD2-CB 3.97Å; F303-A478 WeakPolarHBondContact CD2-O 3.45Å; F303-A478 HydrophobicContact CE2-CB 4.18Å; F303-T481 WeakPolarHBondContact CD2-OG1 3.46Å; F303-L482 HydrophobicContact CD2-CB 4.37Å; F303-L482 HydrophobicContact CE2-CB 4.02Å; F303-L482 HydrophobicContact CE2-CD1 4.21Å; F303-L482 HydrophobicContact CE2-CG 4.49Å; F303-L482 HydrophobicContact CZ-CD1 4.31Å
304	Y	94.7	Very high	94	Very high	8 Å²	8	25.6 Å²	25.6	3%	0.031	12%	0.122	C	C	.	.	H	α-helix	trans	-59.5	-47.3	177.1	171.3	-90.7	0	0	0	111.8	I300 S301 L306 I307 R308 A407 L408 M429 D433	I300-Y304 WeakPolarHBondContact O-CB 3.39Å; I300-Y304 PolarHBondContact O-N 3.09Å; S301-Y304 PolarHBondContact O-N 2.8Å; Y304-L306 PolarHBondContact O-N 3.42Å; Y304-I307 PolarHBondContact O-N 3.06Å; Y304-R308 HydrophobicContact CD1-CG 4.26Å; Y304-R308 HydrophobicContact CE1-CG 3.83Å; Y304-R308 HydrophobicContact CE2-CG 4.15Å; Y304-R308 VanDerWaalsContact CZ-NE 3.35Å; Y304-R308 WeakPolarHBondContact O-CG 3.11Å; Y304-R308 PolarHBondContact O-N 3.44Å; Y304-R308 VanDerWaalsContact OH-CZ 3.24Å; Y304-R308 PolarHBondContact OH-NE 3.25Å; Y304-R308 PolarHBondContact OH-NH2 3.4Å; Y304-A407 HydrophobicContact CD2-CB 4.01Å; Y304-L408 HydrophobicContact CE2-CD2 3.92Å; Y304-M429 HydrophobicContact CD1-CB 3.89Å; Y304-M429 HydrophobicContact CD1-CG 4.48Å; Y304-M429 HydrophobicContact CE1-CB 4.03Å; Y304-M429 HydrophobicContact CG-SD 4.49Å; Y304-D433 HydrophobicContact CE1-CB 4.14Å; Y304-D433 VanDerWaalsContact CE1-OD2 3.27Å; Y304-D433 WeakPolarHBondContact CE1-OD2 3.34Å; Y304-D433 PolarHBondContact OH-OD2 3.23Å
305	M	95.2	Very high	94.5	Very high	26 Å²	26	25.8 Å²	25.8	13%	0.128	12%	0.123	C	C	.	.	H	α-helix	trans	-60.5	-43.5	179.5	-73.2	170.7	56.2	0	0	112.5	S301 L302 R308 L309 F432 D433 L436	S301-M305 WeakPolarHBondContact O-CB 3.24Å; S301-M305 WeakPolarHBondContact O-CG 3.46Å; S301-M305 PolarHBondContact O-N 3.15Å; L302-M305 PolarHBondContact O-N 3.04Å; M305-R308 PolarHBondContact O-N 3.35Å; M305-L309 WeakPolarHBondContact O-CB 3.33Å; M305-L309 PolarHBondContact O-N 2.95Å; M305-F432 HydrophobicContact CE-CB 3.54Å; M305-F432 HydrophobicContact CG-CB 4.36Å; M305-F432 HydrophobicContact SD-CB 3.45Å; M305-F432 WeakPolarHBondContact SD-CB 3.35Å; M305-F432 HydrophobicContact SD-CG 4.41Å; M305-D433 HydrophobicContact CB-CB 4.42Å; M305-D433 HydrophobicContact CG-CB 4.01Å; M305-L436 HydrophobicContact CE-CB 4.33Å; M305-L436 HydrophobicContact CE-CD2 3.94Å
306	L	97	Very high	95	Very high	11 Å²	11	20.9 Å²	20.9	6%	0.058	10%	0.097	C	C	.	.	H	α-helix	trans	-68.2	-37.3	-179.4	-70.4	166.4	0	0	0	112.3	L302 F303 Y304 L309 F310 L477 A478	L302-L306 HydrophobicContact CD1-CD1 3.96Å; L302-L306 HydrophobicContact CD1-CG 4.12Å; L302-L306 HydrophobicContact CG-CD1 3.84Å; L302-L306 HydrophobicContact CG-CG 4.44Å; L302-L306 WeakPolarHBondContact O-CB 3.33Å; L302-L306 WeakPolarHBondContact O-CD1 3.42Å; L302-L306 WeakPolarHBondContact O-CG 3.5Å; L302-L306 PolarHBondContact O-N 3.21Å; F303-L306 PolarHBondContact O-N 3.21Å; Y304-L306 PolarHBondContact O-N 3.42Å; L306-L309 PolarHBondContact O-N 3.23Å; L306-F310 PolarHBondContact O-N 3.17Å; L306-L477 HydrophobicContact CD1-CB 3.63Å; L306-L477 HydrophobicContact CD2-CB 4.08Å; L306-L477 HydrophobicContact CD2-CD1 4.2Å; L306-A478 HydrophobicContact CB-CB 3.96Å; L306-A478 HydrophobicContact CD1-CB 4.25Å
307	I	96.9	Very high	95.3	Very high	2 Å²	2	20.5 Å²	20.5	1%	0.01	10%	0.095	C	C	.	.	H	α-helix	trans	-64.5	-44.5	172.7	-74.6	168.9	0	0	0	111	F303 Y304 L309 F310 N311 L403 I404 A407	F303-I307 HydrophobicContact CD1-CD1 3.72Å; F303-I307 HydrophobicContact CD2-CD1 4.21Å; F303-I307 HydrophobicContact CE1-CD1 3.22Å; F303-I307 HydrophobicContact CE2-CD1 3.77Å; F303-I307 HydrophobicContact CG-CD1 4.2Å; F303-I307 HydrophobicContact CZ-CD1 3.25Å; F303-I307 HydrophobicContact CZ-CG1 4.46Å; F303-I307 WeakPolarHBondContact O-CG1 3.47Å; F303-I307 PolarHBondContact O-N 3.26Å; F303-I307 VanDerWaalsContact O-N 3.12Å; Y304-I307 PolarHBondContact O-N 3.06Å; I307-L309 VanDerWaalsContact C-N 3.32Å; I307-L309 PolarHBondContact O-N 3.22Å; I307-F310 PolarHBondContact O-N 3.21Å; I307-N311 PolarHBondContact O-N 2.99Å; I307-N311 PolarHBondContact O-ND2 2.68Å; I307-L403 HydrophobicContact CB-CB 4.48Å; I307-L403 HydrophobicContact CD1-CB 3.94Å; I307-L403 HydrophobicContact CD1-CD2 4.09Å; I307-L403 HydrophobicContact CG1-CB 4.07Å; I307-L403 HydrophobicContact CG1-CD1 4.43Å; I307-L403 HydrophobicContact CG1-CD2 4.42Å; I307-L403 HydrophobicContact CG2-CB 3.61Å; I307-I404 HydrophobicContact CG2-CG1 4.3Å; I307-A407 HydrophobicContact CD1-CB 3.89Å
308	R	95.5	Very high	95.7	Very high	68 Å²	68	20.1 Å²	20.1	26%	0.257	9%	0.093	S	C	.	.	H	α-helix	trans	-61.2	-42.1	175.3	-74.2	-69.4	-161.1	158.1	7.1	111.2	Y304 M305 N311 N312 D433	Y304-R308 HydrophobicContact CD1-CG 4.26Å; Y304-R308 HydrophobicContact CE1-CG 3.83Å; Y304-R308 HydrophobicContact CE2-CG 4.15Å; Y304-R308 VanDerWaalsContact CZ-NE 3.35Å; Y304-R308 WeakPolarHBondContact O-CG 3.11Å; Y304-R308 PolarHBondContact O-N 3.44Å; Y304-R308 VanDerWaalsContact OH-CZ 3.24Å; Y304-R308 PolarHBondContact OH-NE 3.25Å; Y304-R308 PolarHBondContact OH-NH2 3.4Å; M305-R308 PolarHBondContact O-N 3.35Å; R308-N311 PolarHBondContact O-N 3.03Å; R308-N312 VanDerWaalsContact O-CB 3.28Å; R308-N312 WeakPolarHBondContact O-CB 3.36Å; R308-N312 PolarHBondContact O-N 3.32Å; R308-N312 PolarHBondContact O-ND2 2.85Å; R308-N312 PolarHBondContact O-OD1 2.93Å; R308-D433 HydrophobicContact CB-CB 4.07Å; R308-D433 HydrophobicContact CG-CB 4.34Å; R308-D433 IonicContact NE-OD2 3.49Å
309	L	96.1	Very high	95.8	Very high	18 Å²	18	14.6 Å²	14.6	9%	0.094	7%	0.072	C	C	.	.	H	α-helix	trans	-60.7	-48.2	176	-177.6	64.6	0	0	0	111.8	M305 L306 I307 N311 N312 V313 L436 S474	M305-L309 WeakPolarHBondContact O-CB 3.33Å; M305-L309 PolarHBondContact O-N 2.95Å; L306-L309 PolarHBondContact O-N 3.23Å; I307-L309 VanDerWaalsContact C-N 3.32Å; I307-L309 PolarHBondContact O-N 3.22Å; L309-N311 VanDerWaalsContact C-N 3.33Å; L309-N311 PolarHBondContact O-N 3.47Å; L309-N312 PolarHBondContact O-N 2.86Å; L309-V313 HydrophobicContact CD1-CG2 3.67Å; L309-V313 HydrophobicContact CG-CG2 4.19Å; L309-V313 VanDerWaalsContact O-CB 3.3Å; L309-V313 WeakPolarHBondContact O-CB 3.19Å; L309-V313 VanDerWaalsContact O-CG2 3.27Å; L309-V313 WeakPolarHBondContact O-CG2 3.25Å; L309-V313 PolarHBondContact O-N 3.34Å; L309-L436 HydrophobicContact CB-CD2 4.41Å; L309-L436 HydrophobicContact CD1-CG 4.35Å; L309-L436 HydrophobicContact CD2-CD2 3.94Å; L309-L436 HydrophobicContact CD2-CG 4.08Å; L309-S474 WeakPolarHBondContact CD2-OG 3.48Å
310	F	97.7	Very high	95.9	Very high	1 Å²	1	13.7 Å²	13.7	0%	0.004	7%	0.067	C	C	.	.	H	α-helix	trans	-52	-51.5	174.1	161.1	-99.1	0	0	0	111.5	L306 I307 T314 L396 L403 P471 L475	L306-F310 PolarHBondContact O-N 3.17Å; I307-F310 PolarHBondContact O-N 3.21Å; F310-T314 WeakPolarHBondContact O-CB 3.39Å; F310-T314 PolarHBondContact O-N 3.26Å; F310-T314 PolarHBondContact O-OG1 3.35Å; F310-L396 HydrophobicContact CE2-CD2 4.21Å; F310-L396 HydrophobicContact CZ-CD2 3.89Å; F310-L403 HydrophobicContact CD1-CD1 4.4Å; F310-L403 HydrophobicContact CE1-CD1 4.5Å; F310-P471 HydrophobicContact CD2-CB 3.61Å; F310-P471 HydrophobicContact CE2-CB 3.92Å; F310-L475 HydrophobicContact CB-CD2 3.92Å; F310-L475 HydrophobicContact CB-CG 4.17Å; F310-L475 HydrophobicContact CD1-CD2 4.12Å; F310-L475 HydrophobicContact CD2-CD1 3.55Å; F310-L475 HydrophobicContact CD2-CD2 4.06Å; F310-L475 HydrophobicContact CD2-CG 3.67Å; F310-L475 HydrophobicContact CE2-CD1 3.63Å; F310-L475 HydrophobicContact CE2-CG 4.28Å; F310-L475 HydrophobicContact CG-CD1 4.09Å; F310-L475 HydrophobicContact CG-CD2 3.75Å; F310-L475 HydrophobicContact CG-CG 3.89Å; F310-L475 HydrophobicContact CZ-CD1 4.2Å
311	N	96.3	Very high	96	Very high	10 Å²	10	13.6 Å²	13.6	5%	0.053	7%	0.067	C	C	.	.	H	α-helix	trans	-66	-47.7	-177.4	-71.8	-45.2	0	0	0	112.1	I307 R308 L309 T314 M315 A400 I404	I307-N311 PolarHBondContact O-N 2.99Å; I307-N311 PolarHBondContact O-ND2 2.68Å; R308-N311 PolarHBondContact O-N 3.03Å; L309-N311 VanDerWaalsContact C-N 3.33Å; L309-N311 PolarHBondContact O-N 3.47Å; N311-T314 PolarHBondContact O-N 3.36Å; N311-M315 WeakPolarHBondContact O-CB 3.39Å; N311-M315 VanDerWaalsContact O-CG 3.29Å; N311-M315 WeakPolarHBondContact O-CG 3.41Å; N311-M315 PolarHBondContact O-N 3.12Å; N311-A400 VanDerWaalsContact OD1-CA 3.26Å; N311-A400 WeakPolarHBondContact OD1-CA 3.37Å; N311-A400 WeakPolarHBondContact OD1-CB 3.49Å; N311-I404 WeakPolarHBondContact ND2-CD1 3.38Å; N311-I404 VanDerWaalsContact ND2-CG1 3.26Å; N311-I404 WeakPolarHBondContact ND2-CG1 3.36Å
312	N	95.8	Very high	96.1	Very high	22 Å²	22	13 Å²	13	12%	0.118	6%	0.063	C	C	.	.	H	α-helix	trans	-65	-47.7	-177.5	-67.5	-12.5	0	0	0	110.8	F58 R308 L309 T314 M315 T316 T437	F58-N312 HydrophobicContact CE1-CB 4.41Å; R308-N312 VanDerWaalsContact O-CB 3.28Å; R308-N312 WeakPolarHBondContact O-CB 3.36Å; R308-N312 PolarHBondContact O-N 3.32Å; R308-N312 PolarHBondContact O-ND2 2.85Å; R308-N312 PolarHBondContact O-OD1 2.93Å; L309-N312 PolarHBondContact O-N 2.86Å; N312-T314 PolarHBondContact O-N 2.69Å; N312-M315 PolarHBondContact O-N 2.97Å; N312-T316 WeakPolarHBondContact O-CB 3.03Å; N312-T316 PolarHBondContact O-N 2.93Å; N312-T316 PolarHBondContact O-OG1 2.89Å; N312-T437 HydrophobicContact CB-CG2 3.52Å; N312-T437 PolarHBondContact ND2-OG1 2.92Å
313	V	96.3	Very high	95.9	Very high	0 Å²	0	9.6 Å²	9.6	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-61.2	-46.1	177.7	170.2	0	0	0	0	110.7	L309 T316 Y317 V466 I470 P471	L309-V313 HydrophobicContact CD1-CG2 3.67Å; L309-V313 HydrophobicContact CG-CG2 4.19Å; L309-V313 VanDerWaalsContact O-CB 3.3Å; L309-V313 WeakPolarHBondContact O-CB 3.19Å; L309-V313 VanDerWaalsContact O-CG2 3.27Å; L309-V313 WeakPolarHBondContact O-CG2 3.25Å; L309-V313 PolarHBondContact O-N 3.34Å; V313-T316 PolarHBondContact O-N 3.34Å; V313-Y317 HydrophobicContact CG1-CD2 3.97Å; V313-Y317 WeakPolarHBondContact O-CB 3.12Å; V313-Y317 WeakPolarHBondContact O-CD2 3.42Å; V313-Y317 PolarHBondContact O-N 2.96Å; V313-V466 HydrophobicContact CG1-CG1 4.42Å; V313-I470 HydrophobicContact CG1-CB 4.38Å; V313-I470 HydrophobicContact CG1-CG2 4.06Å; V313-I470 HydrophobicContact CG2-CG2 4.15Å; V313-P471 HydrophobicContact CG1-CG 4.14Å
314	T	97.4	Very high	95.6	Very high	5 Å²	5	9.9 Å²	9.9	3%	0.031	5%	0.046	C	C	.	.	H	α-helix	trans	-60.5	-51.3	180	-60.2	0	0	0	0	110.7	F310 N311 N312 T316 L318 L396 M467	F310-T314 WeakPolarHBondContact O-CB 3.39Å; F310-T314 PolarHBondContact O-N 3.26Å; F310-T314 PolarHBondContact O-OG1 3.35Å; N311-T314 PolarHBondContact O-N 3.36Å; N312-T314 PolarHBondContact O-N 2.69Å; T314-T316 VanDerWaalsContact C-N 3.29Å; T314-T316 PolarHBondContact O-N 3.1Å; T314-L318 WeakPolarHBondContact O-CB 3.4Å; T314-L318 PolarHBondContact O-N 3.38Å; T314-L396 HydrophobicContact CG2-CD1 3.56Å; T314-L396 HydrophobicContact CG2-CD2 3.83Å; T314-L396 HydrophobicContact CG2-CG 4.15Å; T314-M467 HydrophobicContact CG2-CE 3.87Å
315	M	95.6	Very high	95.5	Very high	21 Å²	21	9.7 Å²	9.7	10%	0.103	5%	0.046	C	C	.	.	H	α-helix	trans	-63.6	-37	179.7	-70	-63.2	-168.9	0	0	112.3	N311 N312 P319 V340 Y341	N311-M315 WeakPolarHBondContact O-CB 3.39Å; N311-M315 VanDerWaalsContact O-CG 3.29Å; N311-M315 WeakPolarHBondContact O-CG 3.41Å; N311-M315 PolarHBondContact O-N 3.12Å; N312-M315 PolarHBondContact O-N 2.97Å; M315-P319 WeakPolarHBondContact O-CD 3.37Å; M315-V340 HydrophobicContact CE-CB 4.07Å; M315-V340 HydrophobicContact CE-CG1 3.3Å; M315-V340 HydrophobicContact SD-CG1 4.17Å; M315-Y341 HydrophobicContact CE-CD2 4Å; M315-Y341 HydrophobicContact CE-CE2 3.53Å; M315-Y341 HydrophobicContact SD-CE2 3.78Å
316	T	97.2	Very high	95.3	Very high	1 Å²	1	8.7 Å²	8.7	1%	0.006	4%	0.041	C	C	.	.	H	α-helix	trans	-75.4	-33.9	-176.1	-70.3	0	0	0	0	114.8	F58 L62 F80 N312 V313 T314 V441	F58-T316 WeakPolarHBondContact O-CA 3.08Å; F58-T316 PolarHBondContact O-OG1 2.71Å; F58-T316 VanDerWaalsContact O-OG1 3.06Å; L62-T316 HydrophobicContact CD1-CG2 3.27Å; L62-T316 HydrophobicContact CG-CG2 4.22Å; F80-T316 HydrophobicContact CE2-CG2 3.99Å; F80-T316 HydrophobicContact CZ-CG2 4.4Å; N312-T316 WeakPolarHBondContact O-CB 3.03Å; N312-T316 PolarHBondContact O-N 2.93Å; N312-T316 PolarHBondContact O-OG1 2.89Å; V313-T316 PolarHBondContact O-N 3.34Å; T314-T316 VanDerWaalsContact C-N 3.29Å; T314-T316 PolarHBondContact O-N 3.1Å; T316-V441 HydrophobicContact CG2-CG2 4.41Å
317	Y	97.2	Very high	94.9	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-103.3	-11	-178.5	-72.3	-76.3	0	0	0	114.1	L62 V313 L320 Y321 V441 I444 Q445 F463 V466 M467	L62-Y317 HydrophobicContact CD1-CE1 3.97Å; V313-Y317 HydrophobicContact CG1-CD2 3.97Å; V313-Y317 WeakPolarHBondContact O-CB 3.12Å; V313-Y317 WeakPolarHBondContact O-CD2 3.42Å; V313-Y317 PolarHBondContact O-N 2.96Å; Y317-L320 HydrophobicContact CD1-CD1 4.03Å; Y317-L320 HydrophobicContact CE1-CD1 4.31Å; Y317-L320 PolarHBondContact O-N 3.35Å; Y317-L320 VanDerWaalsContact O-N 3.14Å; Y317-Y321 WeakPolarHBondContact O-CB 3.36Å; Y317-Y321 PolarHBondContact O-N 3.01Å; Y317-V441 HydrophobicContact CE2-CG2 4.06Å; Y317-V441 PolarHBondContact OH-O 3.3Å; Y317-I444 HydrophobicContact CD2-CD1 4.48Å; Y317-I444 HydrophobicContact CE1-CG2 3.76Å; Y317-I444 HydrophobicContact CE2-CB 4.44Å; Y317-I444 HydrophobicContact CE2-CD1 3.68Å; Y317-I444 HydrophobicContact CE2-CG2 4.06Å; Y317-I444 VanDerWaalsContact CZ-CG2 3.44Å; Y317-I444 WeakPolarHBondContact OH-CB 2.98Å; Y317-I444 VanDerWaalsContact OH-CG2 3.25Å; Y317-I444 WeakPolarHBondContact OH-CG2 3.21Å; Y317-Q445 VanDerWaalsContact CE1-NE2 3.3Å; Y317-Q445 WeakPolarHBondContact OH-CG 3.36Å; Y317-Q445 PolarHBondContact OH-NE2 2.96Å; Y317-F463 AromaticContact CD1-CD1 3.88Å; Y317-F463 HydrophobicContact CD1-CD1 3.88Å; Y317-F463 AromaticContact CD1-CE1 3.67Å; Y317-F463 HydrophobicContact CD1-CE1 3.67Å; Y317-F463 HydrophobicContact CE1-CD1 4.47Å; Y317-F463 AromaticContact CE1-CE1 3.88Å; Y317-F463 HydrophobicContact CE1-CE1 3.88Å; Y317-V466 HydrophobicContact CD1-CG1 4.24Å; Y317-V466 HydrophobicContact CD2-CG1 3.88Å; Y317-V466 HydrophobicContact CE2-CG1 4.31Å; Y317-V466 HydrophobicContact CG-CG1 3.83Å; Y317-M467 VanDerWaalsContact CB-SD 3.5Å
318	L	97.1	Very high	94.7	Very high	2 Å²	2	14.2 Å²	14.2	1%	0.01	7%	0.07	C	C	.	.	H	α-helix	trans	-54.7	-46.5	178.8	175.7	65.6	0	0	0	112.7	T314 L320 Y321 I322 V336 P337 V340 M380 M467	T314-L318 WeakPolarHBondContact O-CB 3.4Å; T314-L318 PolarHBondContact O-N 3.38Å; L318-L320 PolarHBondContact O-N 3.44Å; L318-Y321 PolarHBondContact O-N 3.41Å; L318-I322 HydrophobicContact CD1-CD1 4.1Å; L318-I322 HydrophobicContact CD1-CG1 4.33Å; L318-I322 HydrophobicContact CG-CD1 3.98Å; L318-I322 WeakPolarHBondContact O-CD1 3.37Å; L318-I322 WeakPolarHBondContact O-CG1 3.36Å; L318-I322 PolarHBondContact O-N 2.91Å; L318-V336 HydrophobicContact CD1-CG1 4.31Å; L318-V336 HydrophobicContact CD2-CG1 4.23Å; L318-P337 HydrophobicContact CD2-CG 4.16Å; L318-V340 HydrophobicContact CD2-CG2 3.9Å; L318-M380 HydrophobicContact CD1-CE 4.14Å; L318-M467 HydrophobicContact CB-CE 3.95Å; L318-M467 HydrophobicContact CD1-CE 4.27Å
319	P	96	Very high	94.5	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-61.7	-41.1	175.2	-32.3	44.1	0	0	0	114.4	S59 Y60 V63 M315 I322 L323 I333 P337	S59-P319 VanDerWaalsContact O-CG 3.31Å; S59-P319 WeakPolarHBondContact O-CG 3.49Å; Y60-P319 HydrophobicContact CE1-CG 4.31Å; V63-P319 HydrophobicContact CG2-CB 3.65Å; M315-P319 WeakPolarHBondContact O-CD 3.37Å; P319-I322 PolarHBondContact O-N 3.27Å; P319-L323 WeakPolarHBondContact O-CG 3.39Å; P319-L323 PolarHBondContact O-N 3.49Å; P319-L323 VanDerWaalsContact O-N 3.1Å; P319-I333 HydrophobicContact CB-CB 4.19Å; P319-I333 HydrophobicContact CB-CG2 4.42Å; P319-P337 HydrophobicContact CG-CG 4.3Å
320	L	94.6	Very high	94.3	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-67.8	-37.1	176.7	-72.1	173.9	0	0	0	111.7	L62 V63 K66 Y317 L318 L323 E324 F463	L62-L320 HydrophobicContact CB-CD1 4.08Å; L62-L320 HydrophobicContact CD1-CD1 4.46Å; V63-L320 HydrophobicContact CG2-CD2 4.18Å; V63-L320 HydrophobicContact CG2-CG 4.22Å; K66-L320 HydrophobicContact CD-CD1 4.32Å; Y317-L320 HydrophobicContact CD1-CD1 4.03Å; Y317-L320 HydrophobicContact CE1-CD1 4.31Å; Y317-L320 PolarHBondContact O-N 3.35Å; Y317-L320 VanDerWaalsContact O-N 3.14Å; L318-L320 PolarHBondContact O-N 3.44Å; L320-L323 PolarHBondContact O-N 3.16Å; L320-E324 WeakPolarHBondContact O-CB 3.18Å; L320-E324 VanDerWaalsContact O-CG 3.29Å; L320-E324 WeakPolarHBondContact O-CG 3.25Å; L320-E324 PolarHBondContact O-N 2.89Å; L320-F463 HydrophobicContact CB-CD1 4.14Å; L320-F463 HydrophobicContact CB-CE1 4.09Å; L320-F463 HydrophobicContact CB-CG 4.46Å; L320-F463 HydrophobicContact CB-CZ 4.35Å; L320-F463 HydrophobicContact CD1-CE1 3.94Å; L320-F463 HydrophobicContact CD1-CZ 4.11Å
321	Y	95.1	Very high	94	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.084	C	C	.	.	I	π-helix	trans	-63.1	-41.3	173.2	171.4	-91.3	0	0	0	112.2	Y317 L318 T325 Q326 M380 I389 K464 M467	Y317-Y321 WeakPolarHBondContact O-CB 3.36Å; Y317-Y321 PolarHBondContact O-N 3.01Å; L318-Y321 PolarHBondContact O-N 3.41Å; Y321-T325 HydrophobicContact CD2-CG2 3.95Å; Y321-T325 HydrophobicContact CE2-CG2 3.67Å; Y321-T325 WeakPolarHBondContact O-CA 3.45Å; Y321-T325 VanDerWaalsContact O-CB 3.26Å; Y321-T325 WeakPolarHBondContact O-CB 3.47Å; Y321-T325 PolarHBondContact O-N 3.04Å; Y321-Q326 HydrophobicContact CD1-CG 3.91Å; Y321-Q326 HydrophobicContact CE1-CG 3.35Å; Y321-Q326 VanDerWaalsContact CZ-NE2 3.33Å; Y321-Q326 PolarHBondContact O-N 2.87Å; Y321-Q326 PolarHBondContact OH-NE2 2.64Å; Y321-M380 HydrophobicContact CD1-CE 3.29Å; Y321-M380 HydrophobicContact CD2-CE 4.03Å; Y321-M380 HydrophobicContact CE1-CE 3.21Å; Y321-M380 HydrophobicContact CE2-CB 4.29Å; Y321-M380 HydrophobicContact CE2-CE 3.94Å; Y321-M380 HydrophobicContact CG-CE 3.71Å; Y321-M380 WeakPolarHBondContact OH-CA 3.27Å; Y321-M380 WeakPolarHBondContact OH-CB 3.42Å; Y321-M380 PolarHBondContact OH-O 2.92Å; Y321-I389 HydrophobicContact CD1-CD1 4.38Å; Y321-I389 HydrophobicContact CE1-CD1 4.12Å; Y321-K464 HydrophobicContact CE2-CB 4.43Å; Y321-K464 HydrophobicContact CE2-CG 4.48Å; Y321-M467 HydrophobicContact CD2-CB 4.04Å; Y321-M467 HydrophobicContact CD2-CG 3.82Å; Y321-M467 HydrophobicContact CE2-CB 4.43Å; Y321-M467 HydrophobicContact CG-CB 4.48Å; Y321-M467 HydrophobicContact CG-CG 3.89Å
322	I	94.6	Very high	93.9	Very high	0 Å²	0	16.9 Å²	16.9	0%	0	9%	0.088	C	C	.	.	I	π-helix	trans	-59.9	-48.1	176.5	-71.5	164.4	0	0	0	111	L318 P319 Q326 N327 L328 N332 I333 V336 I389	L318-I322 HydrophobicContact CD1-CD1 4.1Å; L318-I322 HydrophobicContact CD1-CG1 4.33Å; L318-I322 HydrophobicContact CG-CD1 3.98Å; L318-I322 WeakPolarHBondContact O-CD1 3.37Å; L318-I322 WeakPolarHBondContact O-CG1 3.36Å; L318-I322 PolarHBondContact O-N 2.91Å; P319-I322 PolarHBondContact O-N 3.27Å; I322-Q326 CarbonylContact O-C 3.54Å; I322-N327 PolarHBondContact O-N 3.11Å; I322-L328 HydrophobicContact CG2-CB 3.78Å; I322-L328 HydrophobicContact CG2-CD1 4.25Å; I322-L328 PolarHBondContact O-N 3.03Å; I322-L328 VanDerWaalsContact O-N 3.09Å; I322-N332 HydrophobicContact CG2-CB 3.88Å; I322-I333 HydrophobicContact CG2-CG2 4.07Å; I322-V336 HydrophobicContact CD1-CB 3.66Å; I322-V336 HydrophobicContact CD1-CG1 3.86Å; I322-V336 HydrophobicContact CD1-CG2 4.06Å; I322-I389 HydrophobicContact CD1-CD1 4.38Å; I322-I389 HydrophobicContact CG1-CD1 3.58Å
323	L	91.9	Very high	93.8	Very high	6 Å²	6	15.9 Å²	15.9	3%	0.031	8%	0.083	C	C	.	.	I	π-helix	trans	-73.6	-50.9	-177.7	-65.6	173.4	0	0	0	112	V63 V222 P319 L320 N327 K330 I333	V63-L323 HydrophobicContact CG1-CD1 4.35Å; V222-L323 HydrophobicContact CB-CD1 4.27Å; V222-L323 HydrophobicContact CG2-CD1 3.77Å; V222-L323 HydrophobicContact CG2-CD2 4.39Å; P319-L323 WeakPolarHBondContact O-CG 3.39Å; P319-L323 PolarHBondContact O-N 3.49Å; P319-L323 VanDerWaalsContact O-N 3.1Å; L320-L323 PolarHBondContact O-N 3.16Å; L323-N327 WeakPolarHBondContact O-CA 3.36Å; L323-N327 PolarHBondContact O-N 3.48Å; L323-K330 HydrophobicContact CD2-CB 4.19Å; L323-I333 HydrophobicContact CD1-CG2 3.98Å; L323-I333 HydrophobicContact CD2-CG2 3.66Å; L323-I333 HydrophobicContact CG-CG2 3.63Å
324	E	89.8	Confident	93.7	Very high	7 Å²	7	16 Å²	16	3%	0.033	8%	0.084	C	C	.	.	I	π-helix	trans	-88.8	-35.5	-167.6	-60.6	-72	-169.7	0	0	113.8	K67 L320 R459 N460 F463	K67-E324 WeakPolarHBondContact CE-OE1 3.34Å; K67-E324 VanDerWaalsContact NZ-CD 3.3Å; K67-E324 IonicContact NZ-OE1 3.14Å; K67-E324 PolarHBondContact NZ-OE1 3.32Å; K67-E324 IonicContact NZ-OE2 2.68Å; L320-E324 WeakPolarHBondContact O-CB 3.18Å; L320-E324 VanDerWaalsContact O-CG 3.29Å; L320-E324 WeakPolarHBondContact O-CG 3.25Å; L320-E324 PolarHBondContact O-N 2.89Å; E324-R459 VanDerWaalsContact CD-NE 3.33Å; E324-R459 IonicContact OE1-CZ 3.73Å; E324-R459 IonicContact OE1-NE 2.73Å; E324-R459 PolarHBondContact OE1-NE 2.89Å; E324-R459 IonicContact OE1-NH1 2.86Å; E324-R459 IonicContact OE1-NH2 3.69Å; E324-R459 PolarHBondContact OE1-NH2 2.94Å; E324-R459 IonicContact OE2-CZ 3.33Å; E324-R459 IonicContact OE2-NE 2.69Å; E324-R459 PolarHBondContact OE2-NE 3.02Å; E324-R459 IonicContact OE2-NH2 3.86Å; E324-R459 PolarHBondContact OE2-NH2 3.09Å; E324-N460 PolarHBondContact O-OD1 3.35Å; E324-F463 HydrophobicContact CB-CD2 3.71Å; E324-F463 HydrophobicContact CB-CE2 4.23Å; E324-F463 HydrophobicContact CG-CD2 3.93Å; E324-F463 HydrophobicContact CG-CE2 3.96Å
325	T	91.7	Very high	93.6	Very high	3 Å²	3	16.9 Å²	16.9	2%	0.018	9%	0.089	C	C	.	.	I	π-helix	trans	-97.1	-43.2	-176.1	-60.3	0	0	0	0	111.3	Y321 N460 F463 K464	Y321-T325 HydrophobicContact CD2-CG2 3.95Å; Y321-T325 HydrophobicContact CE2-CG2 3.67Å; Y321-T325 WeakPolarHBondContact O-CA 3.45Å; Y321-T325 VanDerWaalsContact O-CB 3.26Å; Y321-T325 WeakPolarHBondContact O-CB 3.47Å; Y321-T325 PolarHBondContact O-N 3.04Å; T325-N460 WeakPolarHBondContact CB-O 3.36Å; T325-N460 WeakPolarHBondContact CG2-O 3.5Å; T325-N460 PolarHBondContact OG1-O 3.04Å; T325-F463 WeakPolarHBondContact OG1-CB 3.21Å; T325-K464 HydrophobicContact CG2-CB 3.82Å; T325-K464 HydrophobicContact CG2-CD 4.46Å; T325-K464 HydrophobicContact CG2-CG 4.35Å; T325-K464 PolarHBondContact OG1-N 3.5Å
326	Q	92.1	Very high	93.6	Very high	5 Å²	5	15.9 Å²	15.9	2%	0.023	8%	0.084	C	C	.	.	S	Bend	trans	-93.8	-8	-175.3	-61.1	-65.2	-44	0	0	113	Y321 I322 L328 Y382 I389	Y321-Q326 HydrophobicContact CD1-CG 3.91Å; Y321-Q326 HydrophobicContact CE1-CG 3.35Å; Y321-Q326 VanDerWaalsContact CZ-NE2 3.33Å; Y321-Q326 PolarHBondContact O-N 2.87Å; Y321-Q326 PolarHBondContact OH-NE2 2.64Å; I322-Q326 CarbonylContact O-C 3.54Å; Q326-L328 HydrophobicContact CB-CD1 4.06Å; Q326-L328 HydrophobicContact CB-CG 3.83Å; Q326-L328 PolarHBondContact O-N 3.43Å; Q326-L328 VanDerWaalsContact O-N 3.08Å; Q326-Y382 PolarHBondContact NE2-O 2.91Å; Q326-I389 HydrophobicContact CG-CD1 4.27Å
327	N	89.1	Confident	93.6	Very high	99 Å²	99	15.9 Å²	15.9	53%	0.529	8%	0.084	S	C	.	.			trans	48.9	35.3	-179.8	-62.1	-56.4	0	0	0	113	I322 L323	I322-N327 PolarHBondContact O-N 3.11Å; L323-N327 WeakPolarHBondContact O-CA 3.36Å; L323-N327 PolarHBondContact O-N 3.48Å
328	L	91.4	Very high	93.4	Very high	30 Å²	30	17.8 Å²	17.8	16%	0.157	9%	0.094	C	C	.	.			trans	-84.3	154.9	179.5	-66.7	-178.7	0	0	0	110.4	I322 Q326 N332 I389	I322-L328 HydrophobicContact CG2-CB 3.78Å; I322-L328 HydrophobicContact CG2-CD1 4.25Å; I322-L328 PolarHBondContact O-N 3.03Å; I322-L328 VanDerWaalsContact O-N 3.09Å; Q326-L328 HydrophobicContact CB-CD1 4.06Å; Q326-L328 HydrophobicContact CB-CG 3.83Å; Q326-L328 PolarHBondContact O-N 3.43Å; Q326-L328 VanDerWaalsContact O-N 3.08Å; L328-N332 HydrophobicContact CB-CB 4.25Å; L328-I389 HydrophobicContact CD1-CD1 3.96Å; L328-I389 HydrophobicContact CD1-CG2 4.04Å
329	N	91.3	Very high	93.4	Very high	60 Å²	60	18.5 Å²	18.5	32%	0.321	10%	0.1	S	C	.	.			trans	-57.2	143.2	176.7	-172.5	-56.1	0	0	0	110.9	S220 M331 N332	S220-N329 CarbonylContact O-C 3.46Å; S220-N329 WeakPolarHBondContact O-CA 3.38Å; N329-M331 PolarHBondContact O-N 3.22Å; N329-M331 WeakPolarHBondContact OD1-CB 3.18Å; N329-M331 PolarHBondContact OD1-N 2.85Å; N329-N332 WeakPolarHBondContact O-CB 3.4Å; N329-N332 PolarHBondContact O-N 3.17Å
330	K	91.5	Very high	93.4	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	10%	0.101	C	C	.	.	T	Hydrogen-bonded Turn	trans	-50.8	-27.5	174.4	65.5	174.6	-179.5	174.4	0	114.3	V213 D216 H219 S220 V222 D226 L323 N332 I333	V213-K330 WeakPolarHBondContact O-CD 3.14Å; V213-K330 WeakPolarHBondContact O-CE 3.45Å; V213-K330 PolarHBondContact O-NZ 2.91Å; V213-K330 VanDerWaalsContact O-NZ 3.16Å; D216-K330 VanDerWaalsContact CB-NZ 3.33Å; D216-K330 IonicContact OD2-NZ 3.44Å; D216-K330 PolarHBondContact OD2-NZ 3.39Å; H219-K330 VanDerWaalsContact O-CE 3.28Å; H219-K330 WeakPolarHBondContact O-CE 3.37Å; S220-K330 PolarHBondContact O-N 3.18Å; V222-K330 HydrophobicContact CG2-CB 3.87Å; V222-K330 HydrophobicContact CG2-CD 4.48Å; D226-K330 IonicContact OD1-NZ 3.36Å; D226-K330 PolarHBondContact OD1-NZ 2.82Å; D226-K330 IonicContact OD2-NZ 2.67Å; D226-K330 PolarHBondContact OD2-NZ 3.23Å; L323-K330 HydrophobicContact CD2-CB 4.19Å; K330-N332 PolarHBondContact O-N 2.9Å; K330-N332 VanDerWaalsContact O-N 3.15Å; K330-I333 HydrophobicContact CB-CD1 4.42Å; K330-I333 WeakPolarHBondContact O-CD1 3.42Å; K330-I333 WeakPolarHBondContact O-CG1 3.29Å; K330-I333 PolarHBondContact O-N 3.39Å
331	M	92.1	Very high	93.3	Very high	68 Å²	68	20.2 Å²	20.2	34%	0.335	11%	0.107	S	C	.	.	T	Hydrogen-bonded Turn	trans	-50.5	-37.3	169.3	-179.4	178.9	150.1	0	0	112.9	Y210 N329 I333 A334 T335	Y210-M331 HydrophobicContact CD2-CG 3.76Å; Y210-M331 HydrophobicContact CE2-CE 3.45Å; Y210-M331 VanDerWaalsContact CE2-CE 3.45Å; Y210-M331 HydrophobicContact CE2-CG 3.29Å; Y210-M331 HydrophobicContact CE2-SD 3.68Å; Y210-M331 WeakPolarHBondContact OH-CE 3.35Å; N329-M331 PolarHBondContact O-N 3.22Å; N329-M331 WeakPolarHBondContact OD1-CB 3.18Å; N329-M331 PolarHBondContact OD1-N 2.85Å; M331-I333 VanDerWaalsContact C-N 3.26Å; M331-I333 PolarHBondContact O-N 3.02Å; M331-A334 PolarHBondContact O-N 3.4Å; M331-T335 PolarHBondContact O-N 2.82Å
332	N	93.9	Very high	93.2	Very high	25 Å²	25	23.4 Å²	23.4	13%	0.134	12%	0.124	C	C	.	.	H	α-helix	trans	-71.1	-18.3	-177.9	-69.4	-19.5	0	0	0	113.4	I322 L328 N329 K330 A334 T335 V336 Y390	I322-N332 HydrophobicContact CG2-CB 3.88Å; L328-N332 HydrophobicContact CB-CB 4.25Å; N329-N332 WeakPolarHBondContact O-CB 3.4Å; N329-N332 PolarHBondContact O-N 3.17Å; K330-N332 PolarHBondContact O-N 2.9Å; K330-N332 VanDerWaalsContact O-N 3.15Å; N332-A334 PolarHBondContact O-N 3.35Å; N332-T335 WeakPolarHBondContact CA-OG1 3.25Å; N332-V336 HydrophobicContact CB-CG2 4.13Å; N332-V336 VanDerWaalsContact O-CB 3.31Å; N332-V336 WeakPolarHBondContact O-CB 3.3Å; N332-V336 VanDerWaalsContact O-CG2 3.28Å; N332-V336 WeakPolarHBondContact O-CG2 3.32Å; N332-V336 PolarHBondContact O-N 3.16Å; N332-Y390 PolarHBondContact OD1-OH 2.9Å; N332-Y390 VanDerWaalsContact OD1-OH 3.1Å
333	I	94.6	Very high	93.2	Very high	1 Å²	1	24 Å²	24	1%	0.005	13%	0.128	C	C	.	.	H	α-helix	trans	-69.1	-15.8	174.1	83.7	-163.5	0	0	0	112.2	Y60 V209 V222 P319 I322 L323 K330 M331 P337	Y60-I333 HydrophobicContact CE1-CB 4.36Å; Y60-I333 HydrophobicContact CE1-CD1 4.43Å; Y60-I333 HydrophobicContact CE1-CG1 3.91Å; Y60-I333 WeakPolarHBondContact CE1-O 3.43Å; Y60-I333 PolarHBondContact OH-O 2.99Å; V209-I333 HydrophobicContact CG1-CG1 4.47Å; V222-I333 HydrophobicContact CG2-CD1 3.66Å; P319-I333 HydrophobicContact CB-CB 4.19Å; P319-I333 HydrophobicContact CB-CG2 4.42Å; I322-I333 HydrophobicContact CG2-CG2 4.07Å; L323-I333 HydrophobicContact CD1-CG2 3.98Å; L323-I333 HydrophobicContact CD2-CG2 3.66Å; L323-I333 HydrophobicContact CG-CG2 3.63Å; K330-I333 HydrophobicContact CB-CD1 4.42Å; K330-I333 WeakPolarHBondContact O-CD1 3.42Å; K330-I333 WeakPolarHBondContact O-CG1 3.29Å; K330-I333 PolarHBondContact O-N 3.39Å; M331-I333 VanDerWaalsContact C-N 3.26Å; M331-I333 PolarHBondContact O-N 3.02Å; I333-P337 VanDerWaalsContact O-CD 3.29Å; I333-P337 WeakPolarHBondContact O-CD 3.38Å; I333-P337 VanDerWaalsContact O-CG 3.27Å; I333-P337 WeakPolarHBondContact O-CG 3.26Å
334	A	94.2	Very high	93.2	Very high	2 Å²	2	24 Å²	24	2%	0.017	13%	0.128	C	C	.	.	H	α-helix	trans	-96.1	-48	174.2	0	0	0	0	0	111.6	Y60 F206 V209 Y210 M331 N332 L338	Y60-A334 WeakPolarHBondContact OH-CA 3.37Å; F206-A334 WeakPolarHBondContact O-CB 3.27Å; V209-A334 HydrophobicContact CB-CB 4.48Å; V209-A334 HydrophobicContact CG1-CB 4.31Å; Y210-A334 HydrophobicContact CD2-CB 4.4Å; M331-A334 PolarHBondContact O-N 3.4Å; N332-A334 PolarHBondContact O-N 3.35Å; A334-L338 VanDerWaalsContact O-CB 3.24Å; A334-L338 WeakPolarHBondContact O-CB 3.33Å; A334-L338 PolarHBondContact O-N 3.01Å
335	T	94.6	Very high	93.2	Very high	25 Å²	25	26.6 Å²	26.6	15%	0.153	14%	0.14	C	C	.	.	H	α-helix	trans	-74	-33.5	-173	58.6	0	0	0	0	113.6	Y210 M331 N332 L338 A339 Y390	Y210-T335 HydrophobicContact CD2-CG2 3.81Å; Y210-T335 HydrophobicContact CE2-CG2 3.92Å; M331-T335 PolarHBondContact O-N 2.82Å; N332-T335 WeakPolarHBondContact CA-OG1 3.25Å; T335-L338 WeakPolarHBondContact O-CB 3.31Å; T335-A339 PolarHBondContact O-N 3.29Å; T335-Y390 WeakPolarHBondContact CB-OH 3.28Å; T335-Y390 PolarHBondContact OG1-OH 2.91Å
336	V	96.5	Very high	93.3	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-73.2	-50.4	-178.3	179.6	0	0	0	0	111.2	L318 I322 N332 L338 A339 V340 I389 Y390 A393	L318-V336 HydrophobicContact CD1-CG1 4.31Å; L318-V336 HydrophobicContact CD2-CG1 4.23Å; I322-V336 HydrophobicContact CD1-CB 3.66Å; I322-V336 HydrophobicContact CD1-CG1 3.86Å; I322-V336 HydrophobicContact CD1-CG2 4.06Å; N332-V336 HydrophobicContact CB-CG2 4.13Å; N332-V336 VanDerWaalsContact O-CB 3.31Å; N332-V336 WeakPolarHBondContact O-CB 3.3Å; N332-V336 VanDerWaalsContact O-CG2 3.28Å; N332-V336 WeakPolarHBondContact O-CG2 3.32Å; N332-V336 PolarHBondContact O-N 3.16Å; V336-L338 VanDerWaalsContact C-N 3.25Å; V336-L338 PolarHBondContact O-N 2.93Å; V336-A339 WeakPolarHBondContact O-CB 3.28Å; V336-A339 PolarHBondContact O-N 3.18Å; V336-A339 VanDerWaalsContact O-N 3.07Å; V336-V340 PolarHBondContact O-N 3.36Å; V336-I389 HydrophobicContact CG1-CD1 4.45Å; V336-I389 HydrophobicContact CG1-CG1 4.09Å; V336-I389 HydrophobicContact CG1-CG2 4.48Å; V336-I389 HydrophobicContact CG2-CG2 3.77Å; V336-Y390 HydrophobicContact CG2-CD1 4.23Å; V336-Y390 HydrophobicContact CG2-CE1 3.82Å; V336-Y390 HydrophobicContact CG2-CE2 4.48Å; V336-A393 HydrophobicContact CG1-CB 3.74Å
337	P	95.7	Very high	93.3	Very high	1 Å²	1	33.3 Å²	33.3	1%	0.006	17%	0.17	C	C	.	.	H	α-helix	trans	-56.9	-38.7	170.4	-27.6	38.2	0	0	0	112.8	F206 L318 P319 I333 A339 V340 Y341	F206-P337 HydrophobicContact CD1-CB 4.26Å; F206-P337 HydrophobicContact CE1-CB 3.73Å; F206-P337 HydrophobicContact CE2-CB 4.13Å; F206-P337 HydrophobicContact CZ-CB 3.66Å; L318-P337 HydrophobicContact CD2-CG 4.16Å; P319-P337 HydrophobicContact CG-CG 4.3Å; I333-P337 VanDerWaalsContact O-CD 3.29Å; I333-P337 WeakPolarHBondContact O-CD 3.38Å; I333-P337 VanDerWaalsContact O-CG 3.27Å; I333-P337 WeakPolarHBondContact O-CG 3.26Å; P337-A339 VanDerWaalsContact C-N 3.28Å; P337-A339 PolarHBondContact O-N 2.95Å; P337-V340 WeakPolarHBondContact O-CA 3.36Å; P337-V340 VanDerWaalsContact O-CB 3.29Å; P337-V340 WeakPolarHBondContact O-CB 3.49Å; P337-V340 PolarHBondContact O-N 3.41Å; P337-Y341 WeakPolarHBondContact O-CD2 3.48Å; P337-Y341 PolarHBondContact O-N 2.63Å; P337-Y341 VanDerWaalsContact O-N 3.09Å
338	L	94	Very high	93.2	Very high	39 Å²	39	29.2 Å²	29.2	20%	0.204	15%	0.149	C	C	.	.	H	α-helix	trans	-55	-43.3	173.8	176.8	65.7	0	0	0	112	I203 F206 A334 T335 V336 V340 Y341 I342	I203-L338 HydrophobicContact CB-CD1 4.03Å; I203-L338 HydrophobicContact CG1-CD1 3.68Å; I203-L338 HydrophobicContact CG2-CD1 4.06Å; F206-L338 HydrophobicContact CB-CB 4.08Å; F206-L338 HydrophobicContact CB-CD1 4.37Å; F206-L338 HydrophobicContact CD2-CB 4.12Å; F206-L338 HydrophobicContact CD2-CD1 4.31Å; F206-L338 HydrophobicContact CG-CB 4.35Å; A334-L338 VanDerWaalsContact O-CB 3.24Å; A334-L338 WeakPolarHBondContact O-CB 3.33Å; A334-L338 PolarHBondContact O-N 3.01Å; T335-L338 WeakPolarHBondContact O-CB 3.31Å; V336-L338 VanDerWaalsContact C-N 3.25Å; V336-L338 PolarHBondContact O-N 2.93Å; L338-V340 VanDerWaalsContact C-N 3.31Å; L338-V340 PolarHBondContact O-N 2.93Å; L338-Y341 PolarHBondContact O-N 3.33Å; L338-I342 HydrophobicContact CD1-CD1 3.98Å; L338-I342 HydrophobicContact CD1-CG1 4.2Å; L338-I342 HydrophobicContact CD2-CD1 4.43Å; L338-I342 HydrophobicContact CG-CD1 3.79Å; L338-I342 HydrophobicContact CG-CG1 4.4Å; L338-I342 WeakPolarHBondContact O-CG1 3.18Å; L338-I342 PolarHBondContact O-N 3.11Å
339	A	96.2	Very high	93	Very high	17 Å²	17	30.5 Å²	30.5	14%	0.14	16%	0.158	C	C	.	.	H	α-helix	trans	-62.6	-35	175.5	0	0	0	0	0	113.1	T335 V336 P337 S343 Y390 A393	T335-A339 PolarHBondContact O-N 3.29Å; V336-A339 WeakPolarHBondContact O-CB 3.28Å; V336-A339 PolarHBondContact O-N 3.18Å; V336-A339 VanDerWaalsContact O-N 3.07Å; P337-A339 VanDerWaalsContact C-N 3.28Å; P337-A339 PolarHBondContact O-N 2.95Å; A339-S343 WeakPolarHBondContact O-CB 2.96Å; A339-S343 PolarHBondContact O-N 3.26Å; A339-S343 PolarHBondContact O-OG 3.17Å; A339-Y390 HydrophobicContact CB-CD1 4.2Å; A339-A393 HydrophobicContact CB-CB 4.02Å
340	V	96	Very high	92.8	Very high	2 Å²	2	32.1 Å²	32.1	1%	0.012	17%	0.167	C	C	.	.	H	α-helix	trans	-61.9	-44.9	173	-171.3	0	0	0	0	110.7	M315 L318 V336 P337 L338 S343 S344 A393 L396 G397	M315-V340 HydrophobicContact CE-CB 4.07Å; M315-V340 HydrophobicContact CE-CG1 3.3Å; M315-V340 HydrophobicContact SD-CG1 4.17Å; L318-V340 HydrophobicContact CD2-CG2 3.9Å; V336-V340 PolarHBondContact O-N 3.36Å; P337-V340 WeakPolarHBondContact O-CA 3.36Å; P337-V340 VanDerWaalsContact O-CB 3.29Å; P337-V340 WeakPolarHBondContact O-CB 3.49Å; P337-V340 PolarHBondContact O-N 3.41Å; L338-V340 VanDerWaalsContact C-N 3.31Å; L338-V340 PolarHBondContact O-N 2.93Å; V340-S343 PolarHBondContact O-OG 3.2Å; V340-S344 VanDerWaalsContact O-CB 3.32Å; V340-S344 WeakPolarHBondContact O-CB 3.12Å; V340-S344 PolarHBondContact O-N 3.4Å; V340-S344 PolarHBondContact O-OG 3.44Å; V340-A393 WeakPolarHBondContact CA-O 3.37Å; V340-A393 HydrophobicContact CG2-CB 3.66Å; V340-L396 HydrophobicContact CG1-CB 4.3Å; V340-G397 WeakPolarHBondContact O-CA 3.38Å
341	Y	92.3	Very high	92.4	Very high	35 Å²	35	33.3 Å²	33.3	14%	0.137	17%	0.172	C	C	.	.	H	α-helix	trans	-73	-38	-178.7	-82.3	-94.2	0	0	0	113.2	S202 F206 M315 P337 L338 S344 F345	S202-Y341 VanDerWaalsContact CB-CD1 3.47Å; S202-Y341 WeakPolarHBondContact OG-CD1 3.46Å; S202-Y341 WeakPolarHBondContact OG-CE1 3.26Å; F206-Y341 HydrophobicContact CD2-CD2 4.41Å; F206-Y341 AromaticContact CE2-CD2 3.35Å; F206-Y341 HydrophobicContact CE2-CD2 3.35Å; F206-Y341 AromaticContact CE2-CE2 3.54Å; F206-Y341 HydrophobicContact CE2-CE2 3.54Å; F206-Y341 HydrophobicContact CE2-CG 4.05Å; F206-Y341 AromaticContact CZ-CD2 3.91Å; F206-Y341 HydrophobicContact CZ-CD2 3.91Å; F206-Y341 AromaticContact CZ-CE2 3.63Å; F206-Y341 HydrophobicContact CZ-CE2 3.63Å; M315-Y341 HydrophobicContact CE-CD2 4Å; M315-Y341 HydrophobicContact CE-CE2 3.53Å; M315-Y341 HydrophobicContact SD-CE2 3.78Å; P337-Y341 WeakPolarHBondContact O-CD2 3.48Å; P337-Y341 PolarHBondContact O-N 2.63Å; P337-Y341 VanDerWaalsContact O-N 3.09Å; L338-Y341 PolarHBondContact O-N 3.33Å; Y341-S344 PolarHBondContact O-N 3.14Å; Y341-F345 WeakPolarHBondContact O-CB 3.18Å; Y341-F345 PolarHBondContact O-N 2.88Å
342	I	93	Very high	91.7	Very high	67 Å²	67	34.5 Å²	34.5	34%	0.344	19%	0.187	S	C	.	.	H	α-helix	trans	-61.8	-47.8	175.1	-69.5	171.9	0	0	0	110.3	L338 F345 F346	L338-I342 HydrophobicContact CD1-CD1 3.98Å; L338-I342 HydrophobicContact CD1-CG1 4.2Å; L338-I342 HydrophobicContact CD2-CD1 4.43Å; L338-I342 HydrophobicContact CG-CD1 3.79Å; L338-I342 HydrophobicContact CG-CG1 4.4Å; L338-I342 WeakPolarHBondContact O-CG1 3.18Å; L338-I342 PolarHBondContact O-N 3.11Å; I342-F345 WeakPolarHBondContact O-CB 3.5Å; I342-F345 PolarHBondContact O-N 3.17Å; I342-F346 HydrophobicContact CG2-CD2 3.84Å; I342-F346 HydrophobicContact CG2-CE2 3.61Å; I342-F346 WeakPolarHBondContact O-CD2 3.42Å; I342-F346 PolarHBondContact O-N 3.38Å; I342-F346 VanDerWaalsContact O-N 3.13Å
343	S	95.6	Very high	90.9	Very high	12 Å²	12	39.3 Å²	39.3	8%	0.084	21%	0.207	C	C	.	.	H	α-helix	trans	-65.9	-38.3	177.2	54.9	0	0	0	0	112.6	A339 V340 F345 T347 I394 G397	A339-S343 WeakPolarHBondContact O-CB 2.96Å; A339-S343 PolarHBondContact O-N 3.26Å; A339-S343 PolarHBondContact O-OG 3.17Å; V340-S343 PolarHBondContact O-OG 3.2Å; S343-F345 VanDerWaalsContact C-N 3.32Å; S343-F345 PolarHBondContact O-N 2.96Å; S343-T347 WeakPolarHBondContact O-CB 3.48Å; S343-T347 PolarHBondContact O-N 3.41Å; S343-T347 PolarHBondContact O-OG1 3.15Å; S343-I394 PolarHBondContact OG-O 3.23Å; S343-G397 WeakPolarHBondContact OG-CA 3.34Å
344	S	92.6	Very high	89.7	Confident	6 Å²	6	46.4 Å²	46.4	4%	0.042	23%	0.233	C	C	.	.	H	α-helix	trans	-58.7	-43.2	172.5	-60	0	0	0	0	111.8	V340 Y341 T347 S348 G397 A401	V340-S344 VanDerWaalsContact O-CB 3.32Å; V340-S344 WeakPolarHBondContact O-CB 3.12Å; V340-S344 PolarHBondContact O-N 3.4Å; V340-S344 PolarHBondContact O-OG 3.44Å; Y341-S344 PolarHBondContact O-N 3.14Å; S344-T347 PolarHBondContact O-N 3.15Å; S344-S348 WeakPolarHBondContact O-CB 3.28Å; S344-S348 PolarHBondContact O-N 3.37Å; S344-G397 WeakPolarHBondContact CA-O 3.45Å; S344-G397 WeakPolarHBondContact OG-CA 3.38Å; S344-G397 PolarHBondContact OG-O 3.25Å; S344-G397 VanDerWaalsContact OG-O 3.09Å; S344-A401 WeakPolarHBondContact O-CB 3.43Å
345	F	89.6	Confident	88.3	Confident	61 Å²	61	54.8 Å²	54.8	27%	0.268	27%	0.266	S	S	.	.	H	α-helix	trans	-61.8	-54.2	178.3	173.6	-104.3	0	0	0	112.4	A196 V199 Y341 I342 S343 T347 S348 T349	A196-F345 HydrophobicContact CB-CE2 4.26Å; V199-F345 HydrophobicContact CB-CB 4.24Å; V199-F345 HydrophobicContact CB-CD2 4.01Å; V199-F345 HydrophobicContact CB-CG 4.39Å; V199-F345 HydrophobicContact CG1-CB 3.63Å; V199-F345 HydrophobicContact CG1-CD2 3.96Å; V199-F345 HydrophobicContact CG1-CG 3.87Å; V199-F345 HydrophobicContact CG2-CB 3.78Å; V199-F345 HydrophobicContact CG2-CD2 3.87Å; V199-F345 HydrophobicContact CG2-CG 4.25Å; Y341-F345 WeakPolarHBondContact O-CB 3.18Å; Y341-F345 PolarHBondContact O-N 2.88Å; I342-F345 WeakPolarHBondContact O-CB 3.5Å; I342-F345 PolarHBondContact O-N 3.17Å; S343-F345 VanDerWaalsContact C-N 3.32Å; S343-F345 PolarHBondContact O-N 2.96Å; F345-T347 PolarHBondContact O-N 3.31Å; F345-S348 PolarHBondContact O-N 2.92Å; F345-S348 VanDerWaalsContact O-N 3.11Å; F345-S348 PolarHBondContact O-OG 2.86Å; F345-T349 PolarHBondContact O-N 3.29Å; F345-T349 PolarHBondContact O-OG1 2.65Å; F345-T349 VanDerWaalsContact O-OG1 3.14Å
346	F	92.1	Very high	87	Confident	136 Å²	136	55.3 Å²	55.3	60%	0.596	27%	0.269	S	S	*	.	H	α-helix	trans	-59.9	-37.7	179.1	-74.9	-66.6	0	0	0	111.9	I342 T349 L350	I342-F346 HydrophobicContact CG2-CD2 3.84Å; I342-F346 HydrophobicContact CG2-CE2 3.61Å; I342-F346 WeakPolarHBondContact O-CD2 3.42Å; I342-F346 PolarHBondContact O-N 3.38Å; I342-F346 VanDerWaalsContact O-N 3.13Å; F346-T349 PolarHBondContact O-N 3.37Å; F346-L350 WeakPolarHBondContact O-CB 2.97Å; F346-L350 PolarHBondContact O-N 3.42Å
347	T	92.2	Very high	85.6	Confident	13 Å²	13	58.4 Å²	58.4	8%	0.08	29%	0.288	C	S	.	.	H	α-helix	trans	-64.8	-43.9	175.3	-55.1	0	0	0	0	111.7	S343 S344 F345 T349 L350 F351 I398 A401 I402	S343-T347 WeakPolarHBondContact O-CB 3.48Å; S343-T347 PolarHBondContact O-N 3.41Å; S343-T347 PolarHBondContact O-OG1 3.15Å; S344-T347 PolarHBondContact O-N 3.15Å; F345-T347 PolarHBondContact O-N 3.31Å; T347-T349 PolarHBondContact O-N 2.93Å; T347-L350 WeakPolarHBondContact O-CB 3.33Å; T347-L350 PolarHBondContact O-N 2.97Å; T347-F351 HydrophobicContact CG2-CD2 4.13Å; T347-F351 HydrophobicContact CG2-CE2 4.26Å; T347-F351 WeakPolarHBondContact O-CD2 3.42Å; T347-F351 PolarHBondContact O-N 3.48Å; T347-I398 HydrophobicContact CG2-CG2 4.24Å; T347-I398 WeakPolarHBondContact OG1-CG1 3.2Å; T347-A401 HydrophobicContact CG2-CB 3.86Å; T347-I402 HydrophobicContact CG2-CD1 4.27Å; T347-I402 HydrophobicContact CG2-CG1 3.7Å
348	S	88.7	Confident	84.1	Confident	14 Å²	14	67.9 Å²	67.9	10%	0.098	32%	0.324	C	S	.	.	H	α-helix	trans	-62.9	-41.4	177.6	76.7	0	0	0	0	112.5	Y195 S344 F345 L350 F351 S352	Y195-S348 WeakPolarHBondContact CD1-OG 3.41Å; Y195-S348 WeakPolarHBondContact CE1-OG 3.49Å; S344-S348 WeakPolarHBondContact O-CB 3.28Å; S344-S348 PolarHBondContact O-N 3.37Å; F345-S348 PolarHBondContact O-N 2.92Å; F345-S348 VanDerWaalsContact O-N 3.11Å; F345-S348 PolarHBondContact O-OG 2.86Å; S348-L350 VanDerWaalsContact C-N 3.34Å; S348-F351 PolarHBondContact O-N 2.78Å; S348-S352 PolarHBondContact O-N 3.02Å
349	T	86.8	Confident	82.7	Confident	57 Å²	57	70.8 Å²	70.8	35%	0.35	34%	0.343	S	S	.	.	H	α-helix	trans	-65.2	-41.3	177.1	-59.1	0	0	0	0	110	F345 F346 T347 F351 S352 F353	F345-T349 PolarHBondContact O-N 3.29Å; F345-T349 PolarHBondContact O-OG1 2.65Å; F345-T349 VanDerWaalsContact O-OG1 3.14Å; F346-T349 PolarHBondContact O-N 3.37Å; T347-T349 PolarHBondContact O-N 2.93Å; T349-F351 PolarHBondContact O-N 3.37Å; T349-S352 VanDerWaalsContact O-CB 3.26Å; T349-S352 WeakPolarHBondContact O-CB 3.03Å; T349-S352 PolarHBondContact O-N 3.47Å; T349-S352 VanDerWaalsContact O-N 3.16Å; T349-F353 HydrophobicContact CG2-CE2 4.38Å; T349-F353 VanDerWaalsContact O-CD2 3.25Å; T349-F353 WeakPolarHBondContact O-CD2 3.28Å
350	L	87.4	Confident	81.6	Confident	94 Å²	94	71.2 Å²	71.2	49%	0.492	35%	0.345	S	S	.	.	H	α-helix	trans	-59.4	-44.7	174.4	-178	64.1	0	0	0	111.9	F346 T347 S348 S352 F353 V356	F346-L350 WeakPolarHBondContact O-CB 2.97Å; F346-L350 PolarHBondContact O-N 3.42Å; T347-L350 WeakPolarHBondContact O-CB 3.33Å; T347-L350 PolarHBondContact O-N 2.97Å; S348-L350 VanDerWaalsContact C-N 3.34Å; L350-S352 VanDerWaalsContact C-N 3.28Å; L350-S352 PolarHBondContact O-N 3.46Å; L350-F353 WeakPolarHBondContact O-CB 3.49Å; L350-F353 PolarHBondContact O-N 3.48Å; L350-V356 HydrophobicContact CD1-CG2 4.08Å; L350-V356 HydrophobicContact CG-CG2 4.27Å; L350-V356 WeakPolarHBondContact O-CG2 3.5Å
351	F	83	Confident	81.1	Confident	24 Å²	24	73.2 Å²	73.2	11%	0.105	37%	0.366	C	S	.	.	H	α-helix	trans	-72	-20.1	177.3	-89.1	-102.3	0	0	0	113.6	T347 S348 T349 F353 V356 T357 I402 I405	T347-F351 HydrophobicContact CG2-CD2 4.13Å; T347-F351 HydrophobicContact CG2-CE2 4.26Å; T347-F351 WeakPolarHBondContact O-CD2 3.42Å; T347-F351 PolarHBondContact O-N 3.48Å; S348-F351 PolarHBondContact O-N 2.78Å; T349-F351 PolarHBondContact O-N 3.37Å; F351-F353 PolarHBondContact O-N 3.39Å; F351-V356 HydrophobicContact CD1-CG1 4.45Å; F351-V356 HydrophobicContact CD2-CG1 4.47Å; F351-V356 HydrophobicContact CE1-CG1 4.45Å; F351-V356 HydrophobicContact CE2-CG1 4.46Å; F351-V356 HydrophobicContact CG-CG1 4.47Å; F351-V356 HydrophobicContact CZ-CG1 4.46Å; F351-T357 HydrophobicContact CD1-CG2 4.36Å; F351-T357 WeakPolarHBondContact O-CG2 3.31Å; F351-I402 HydrophobicContact CD2-CG1 4.36Å; F351-I402 HydrophobicContact CE2-CD1 4.06Å; F351-I402 HydrophobicContact CE2-CG1 3.61Å; F351-I402 HydrophobicContact CZ-CD1 4.2Å; F351-I402 HydrophobicContact CZ-CG1 3.78Å; F351-I402 HydrophobicContact CZ-CG2 4.22Å; F351-I405 HydrophobicContact CB-CD1 4.12Å
352	S	77.6	Confident	80.8	Confident	94 Å²	94	76.2 Å²	76.2	66%	0.657	38%	0.377	S	S	*	.	H	α-helix	trans	-64.9	-27.9	172.5	-164	0	0	0	0	112	S348 T349 L350 R354	S348-S352 PolarHBondContact O-N 3.02Å; T349-S352 VanDerWaalsContact O-CB 3.26Å; T349-S352 WeakPolarHBondContact O-CB 3.03Å; T349-S352 PolarHBondContact O-N 3.47Å; T349-S352 VanDerWaalsContact O-N 3.16Å; L350-S352 VanDerWaalsContact C-N 3.28Å; L350-S352 PolarHBondContact O-N 3.46Å; S352-R354 PolarHBondContact O-N 3.26Å
353	F	76.8	Confident	80.7	Confident	126 Å²	126	75 Å²	75	55%	0.553	37%	0.369	S	S	*	.	S	Bend	trans	-66.2	118.8	173.7	-67	-77	0	0	0	111.1	T349 L350 F351 Y355 V356	T349-F353 HydrophobicContact CG2-CE2 4.38Å; T349-F353 VanDerWaalsContact O-CD2 3.25Å; T349-F353 WeakPolarHBondContact O-CD2 3.28Å; L350-F353 WeakPolarHBondContact O-CB 3.49Å; L350-F353 PolarHBondContact O-N 3.48Å; F351-F353 PolarHBondContact O-N 3.39Å; F353-Y355 PolarHBondContact O-N 3.5Å; F353-V356 HydrophobicContact CB-CG2 4.43Å; F353-V356 PolarHBondContact O-N 2.95Å
354	R	68.8	Low	80.6	Confident	149 Å²	149	78.5 Å²	78.5	56%	0.562	39%	0.386	S	S	*	.	H	α-helix	trans	-53.1	-26.7	179.4	-72.3	-175.4	174.7	172.7	-2.2	113.9	D185 S352 T357 R358	D185-R354 IonicContact OD1-NH2 3.37Å; D185-R354 PolarHBondContact OD1-NH2 2.9Å; D185-R354 IonicContact OD2-NH2 2.72Å; S352-R354 PolarHBondContact O-N 3.26Å; R354-T357 WeakPolarHBondContact CA-OG1 3.32Å; R354-T357 PolarHBondContact O-OG1 2.87Å; R354-R358 WeakPolarHBondContact O-CB 3.26Å; R354-R358 VanDerWaalsContact O-CG 3.28Å; R354-R358 WeakPolarHBondContact O-CG 3.28Å; R354-R358 PolarHBondContact O-N 3.33Å
355	Y	64.9	Low	80.6	Confident	178 Å²	178	78.4 Å²	78.4	70%	0.698	39%	0.385	S	S	*	.	H	α-helix	trans	-63.7	-47	177.3	-176.6	-97.5	0	0	0	111.8	F353 T357 R358 V359	F353-Y355 PolarHBondContact O-N 3.5Å; Y355-T357 PolarHBondContact O-N 2.95Å; Y355-R358 PolarHBondContact O-N 3.37Å; Y355-V359 HydrophobicContact CD1-CG2 4.38Å; Y355-V359 HydrophobicContact CD2-CG2 4.42Å; Y355-V359 HydrophobicContact CE1-CG2 4.05Å; Y355-V359 HydrophobicContact CE2-CG2 4.1Å; Y355-V359 WeakPolarHBondContact O-CG2 2.8Å; Y355-V359 PolarHBondContact O-N 3.31Å
356	V	66.4	Low	80.8	Confident	36 Å²	36	75.5 Å²	75.5	22%	0.218	37%	0.373	C	S	.	.	H	α-helix	trans	-64.4	-43.2	-177.7	178.9	0	0	0	0	110.9	L350 F351 F353 S360	L350-V356 HydrophobicContact CD1-CG2 4.08Å; L350-V356 HydrophobicContact CG-CG2 4.27Å; L350-V356 WeakPolarHBondContact O-CG2 3.5Å; F351-V356 HydrophobicContact CD1-CG1 4.45Å; F351-V356 HydrophobicContact CD2-CG1 4.47Å; F351-V356 HydrophobicContact CE1-CG1 4.45Å; F351-V356 HydrophobicContact CE2-CG1 4.46Å; F351-V356 HydrophobicContact CG-CG1 4.47Å; F351-V356 HydrophobicContact CZ-CG1 4.46Å; F353-V356 HydrophobicContact CB-CG2 4.43Å; F353-V356 PolarHBondContact O-N 2.95Å; V356-S360 WeakPolarHBondContact O-CB 3.3Å; V356-S360 PolarHBondContact O-N 2.89Å
357	T	68.2	Low	81.1	Confident	65 Å²	65	71.3 Å²	71.3	40%	0.399	36%	0.356	S	S	.	.	H	α-helix	trans	-74	-24.2	179.4	47.2	0	0	0	0	114.1	F351 R354 Y355 S360	F351-T357 HydrophobicContact CD1-CG2 4.36Å; F351-T357 WeakPolarHBondContact O-CG2 3.31Å; R354-T357 WeakPolarHBondContact CA-OG1 3.32Å; R354-T357 PolarHBondContact O-OG1 2.87Å; Y355-T357 PolarHBondContact O-N 2.95Å; T357-S360 VanDerWaalsContact O-O 3.07Å
358	R	64	Low	81.2	Confident	200 Å²	200	73.8 Å²	73.8	76%	0.755	37%	0.371	S	S	*	.	H	α-helix	trans	-77.1	-41.7	172.4	-82.1	-179.6	-179.7	161.7	-0.7	112.3	R354 Y355	R354-R358 WeakPolarHBondContact O-CB 3.26Å; R354-R358 VanDerWaalsContact O-CG 3.28Å; R354-R358 WeakPolarHBondContact O-CG 3.28Å; R354-R358 PolarHBondContact O-N 3.33Å; Y355-R358 PolarHBondContact O-N 3.37Å
359	V	64	Low	81.6	Confident	100 Å²	100	73.1 Å²	73.1	61%	0.606	37%	0.367	S	S	*	.	H	α-helix	trans	-75.3	-40.8	-178.2	176	0	0	0	0	110.8	Y355	Y355-V359 HydrophobicContact CD1-CG2 4.38Å; Y355-V359 HydrophobicContact CD2-CG2 4.42Å; Y355-V359 HydrophobicContact CE1-CG2 4.05Å; Y355-V359 HydrophobicContact CE2-CG2 4.1Å; Y355-V359 WeakPolarHBondContact O-CG2 2.8Å; Y355-V359 PolarHBondContact O-N 3.31Å
360	S	74.4	Confident	82.2	Confident	27 Å²	27	70.6 Å²	70.6	19%	0.189	35%	0.351	C	S	.	.	S	Bend	trans	-96	107.7	176.3	-176	0	0	0	0	110.4	V356 T357 S365	V356-S360 WeakPolarHBondContact O-CB 3.3Å; V356-S360 PolarHBondContact O-N 2.89Å; T357-S360 VanDerWaalsContact O-O 3.07Å; S360-S365 WeakPolarHBondContact OG-CB 3.29Å; S360-S365 PolarHBondContact OG-N 3.44Å
361	G	84.6	Confident	82.7	Confident	43 Å²	43	70.6 Å²	70.6	44%	0.443	35%	0.35	S	S	.	.			trans	-56.1	142.8	168.5	0	0	0	0	0	111.2	K363 L364 S365	G361-K363 PolarHBondContact O-N 2.97Å; G361-K363 VanDerWaalsContact O-N 3.11Å; G361-L364 WeakPolarHBondContact O-CA 3.48Å; G361-L364 WeakPolarHBondContact O-CB 3.35Å; G361-L364 PolarHBondContact O-N 3.45Å; G361-S365 PolarHBondContact O-N 3.07Å; G361-S365 PolarHBondContact O-OG 3.4Å
362	R	86.3	Confident	83.4	Confident	99 Å²	99	71.2 Å²	71.2	37%	0.374	35%	0.354	S	S	.	.	H	α-helix	trans	-52.6	-38.2	-174.6	-62	-179.5	-169.8	-173.7	11.4	113.6	S365 S366 A409 D413	R362-S365 WeakPolarHBondContact CA-OG 3.28Å; R362-S365 PolarHBondContact O-OG 3.48Å; R362-S366 WeakPolarHBondContact O-CB 3.27Å; R362-S366 PolarHBondContact O-N 3.47Å; R362-S366 PolarHBondContact O-OG 3.41Å; R362-A409 PolarHBondContact NH1-O 2.79Å; R362-D413 IonicContact CZ-OD1 2.61Å; R362-D413 VanDerWaalsContact CZ-OD1 3.3Å; R362-D413 IonicContact CZ-OD2 2.66Å; R362-D413 IonicContact NE-OD2 2.74Å; R362-D413 IonicContact NH1-OD1 2.62Å; R362-D413 PolarHBondContact NH1-OD1 3.37Å; R362-D413 IonicContact NH1-OD2 3.38Å; R362-D413 PolarHBondContact NH1-OD2 3.4Å; R362-D413 IonicContact NH2-OD1 3.99Å; R362-D413 PolarHBondContact NH2-OD1 2.8Å; R362-D413 IonicContact NH2-OD2 3.38Å
363	K	91	Very high	84.4	Confident	42 Å²	42	66.7 Å²	66.7	18%	0.183	32%	0.323	C	S	.	.	H	α-helix	trans	-67.7	-39.1	177.3	-64.3	171	173.8	171.6	0	112.3	G361 S366 L367 L482 L485 W486 Q488	G361-K363 PolarHBondContact O-N 2.97Å; G361-K363 VanDerWaalsContact O-N 3.11Å; K363-S366 PolarHBondContact O-N 3.19Å; K363-L367 PolarHBondContact O-N 3.44Å; K363-L482 HydrophobicContact CB-CD1 4.14Å; K363-L482 HydrophobicContact CG-CD1 4.18Å; K363-L485 WeakPolarHBondContact CE-O 3.38Å; K363-L485 PolarHBondContact NZ-O 3.23Å; K363-W486 HydrophobicContact CB-CD2 4.49Å; K363-W486 HydrophobicContact CB-CE3 3.77Å; K363-W486 HydrophobicContact CB-CH2 4.19Å; K363-W486 HydrophobicContact CB-CZ3 3.61Å; K363-W486 HydrophobicContact CD-CD2 4.46Å; K363-W486 HydrophobicContact CD-CE3 4.38Å; K363-W486 PolarHBondContact NZ-O 3.12Å; K363-Q488 PolarHBondContact NZ-O 3.28Å
364	L	92.6	Very high	85.5	Confident	84 Å²	84	62.7 Å²	62.7	44%	0.44	31%	0.309	S	S	.	.	H	α-helix	trans	-69.5	-43.5	177.5	-179.1	63.2	0	0	0	111.3	G361 S366 L367 V368 W486	G361-L364 WeakPolarHBondContact O-CA 3.48Å; G361-L364 WeakPolarHBondContact O-CB 3.35Å; G361-L364 PolarHBondContact O-N 3.45Å; L364-S366 VanDerWaalsContact C-N 3.33Å; L364-S366 PolarHBondContact O-N 3.24Å; L364-L367 HydrophobicContact CD1-CD2 4.46Å; L364-L367 WeakPolarHBondContact O-CB 3.3Å; L364-L367 PolarHBondContact O-N 3.1Å; L364-V368 WeakPolarHBondContact O-CG2 3.39Å; L364-V368 PolarHBondContact O-N 3.48Å; L364-W486 HydrophobicContact CB-CH2 4.32Å; L364-W486 HydrophobicContact CD1-CH2 4.46Å
365	S	92.7	Very high	86.8	Confident	4 Å²	4	59.2 Å²	59.2	3%	0.028	31%	0.306	C	S	.	.	H	α-helix	trans	-63.1	-40.4	174	44.5	0	0	0	0	111.8	S360 G361 R362 L367 V368 G369 I402 N406	S360-S365 WeakPolarHBondContact OG-CB 3.29Å; S360-S365 PolarHBondContact OG-N 3.44Å; G361-S365 PolarHBondContact O-N 3.07Å; G361-S365 PolarHBondContact O-OG 3.4Å; R362-S365 WeakPolarHBondContact CA-OG 3.28Å; R362-S365 PolarHBondContact O-OG 3.48Å; S365-L367 VanDerWaalsContact C-N 3.31Å; S365-L367 PolarHBondContact O-N 2.82Å; S365-V368 PolarHBondContact O-N 2.81Å; S365-G369 PolarHBondContact O-N 3.46Å; S365-I402 WeakPolarHBondContact O-CG2 3.33Å; S365-N406 WeakPolarHBondContact CB-ND2 3.08Å; S365-N406 VanDerWaalsContact OG-CG 3.31Å; S365-N406 PolarHBondContact OG-ND2 3.16Å; S365-N406 PolarHBondContact OG-OD1 2.98Å; S365-N406 VanDerWaalsContact OG-OD1 3.09Å
366	S	95.1	Very high	88.4	Confident	0 Å²	0	50.7 Å²	50.7	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-58	-42.2	172	-71.4	0	0	0	0	112.5	R362 K363 L364 G369 I370 L403 N406	R362-S366 WeakPolarHBondContact O-CB 3.27Å; R362-S366 PolarHBondContact O-N 3.47Å; R362-S366 PolarHBondContact O-OG 3.41Å; K363-S366 PolarHBondContact O-N 3.19Å; L364-S366 VanDerWaalsContact C-N 3.33Å; L364-S366 PolarHBondContact O-N 3.24Å; S366-G369 PolarHBondContact O-N 2.88Å; S366-I370 WeakPolarHBondContact O-CG1 3.27Å; S366-I370 PolarHBondContact O-N 3.33Å; S366-L403 WeakPolarHBondContact O-CD2 3.07Å; S366-N406 WeakPolarHBondContact OG-CB 3.09Å
367	L	96.7	Very high	89.9	Confident	49 Å²	49	49 Å²	49	26%	0.257	26%	0.263	S	S	.	.	H	α-helix	trans	-61.4	-45.1	176	177.4	64	0	0	0	111.6	K363 L364 S365 G369 I370 I371 L479 L482	K363-L367 PolarHBondContact O-N 3.44Å; L364-L367 HydrophobicContact CD1-CD2 4.46Å; L364-L367 WeakPolarHBondContact O-CB 3.3Å; L364-L367 PolarHBondContact O-N 3.1Å; S365-L367 VanDerWaalsContact C-N 3.31Å; S365-L367 PolarHBondContact O-N 2.82Å; L367-G369 PolarHBondContact O-N 3.33Å; L367-I370 PolarHBondContact O-N 3.34Å; L367-I371 HydrophobicContact CD1-CD1 4.21Å; L367-I371 HydrophobicContact CD1-CG1 4.49Å; L367-I371 HydrophobicContact CG-CD1 4.06Å; L367-I371 WeakPolarHBondContact O-CG1 3.48Å; L367-I371 PolarHBondContact O-N 2.88Å; L367-L479 HydrophobicContact CD1-CD1 3.45Å; L367-L479 VanDerWaalsContact CD1-CD1 3.45Å; L367-L482 HydrophobicContact CB-CD2 4.14Å
368	V	95.8	Very high	91.3	Very high	65 Å²	65	47.4 Å²	47.4	39%	0.394	26%	0.259	S	S	.	.	H	α-helix	trans	-60.2	-45.4	175.6	172.8	0	0	0	0	110.9	L364 S365 I370 I371 I372	L364-V368 WeakPolarHBondContact O-CG2 3.39Å; L364-V368 PolarHBondContact O-N 3.48Å; S365-V368 PolarHBondContact O-N 2.81Å; V368-I370 PolarHBondContact O-N 3.35Å; V368-I371 PolarHBondContact O-N 3.02Å; V368-I372 HydrophobicContact CG1-CD1 3.75Å; V368-I372 HydrophobicContact CG1-CG1 4.41Å; V368-I372 VanDerWaalsContact O-CG1 3.3Å; V368-I372 WeakPolarHBondContact O-CG1 3.31Å; V368-I372 PolarHBondContact O-N 3.2Å
369	G	97.4	Very high	92.8	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-58.2	-45.1	175.8	0	0	0	0	0	112.5	S365 S366 L367 I371 I372 G373 S399	S365-G369 PolarHBondContact O-N 3.46Å; S366-G369 PolarHBondContact O-N 2.88Å; L367-G369 PolarHBondContact O-N 3.33Å; G369-I371 PolarHBondContact O-N 2.73Å; G369-I372 PolarHBondContact O-N 3.32Å; G369-G373 PolarHBondContact O-N 3.29Å; G369-S399 PolarHBondContact O-OG 3.26Å
370	I	98.5	Very high	94.4	Very high	3 Å²	3	37.4 Å²	37.4	2%	0.015	21%	0.211	C	C	.	.	H	α-helix	trans	-59.6	-47.8	176.4	-74.9	166.4	0	0	0	110.9	F303 S366 L367 V368 I372 G373 V374 L403 L475 A478 L479 L482	F303-I370 HydrophobicContact CE2-CD1 4.27Å; S366-I370 WeakPolarHBondContact O-CG1 3.27Å; S366-I370 PolarHBondContact O-N 3.33Å; L367-I370 PolarHBondContact O-N 3.34Å; V368-I370 PolarHBondContact O-N 3.35Å; I370-I372 PolarHBondContact O-N 3.28Å; I370-G373 PolarHBondContact O-N 2.89Å; I370-V374 HydrophobicContact CG2-CG2 4.35Å; I370-V374 WeakPolarHBondContact O-CG2 3.44Å; I370-V374 PolarHBondContact O-N 3.43Å; I370-L403 HydrophobicContact CG1-CD2 3.87Å; I370-L475 HydrophobicContact CG1-CD2 4.42Å; I370-L475 HydrophobicContact CG2-CB 4.32Å; I370-A478 HydrophobicContact CD1-CB 4.43Å; I370-L479 HydrophobicContact CD1-CB 4.17Å; I370-L479 HydrophobicContact CD1-CD1 4.31Å; I370-L479 HydrophobicContact CG2-CB 4.24Å; I370-L482 HydrophobicContact CD1-CD2 3.93Å
371	I	98.3	Very high	95.3	Very high	94 Å²	94	41.5 Å²	41.5	48%	0.482	22%	0.222	S	C	.	.	H	α-helix	trans	-60.2	-48.4	-179.6	-68.4	165.9	0	0	0	110.1	L367 V368 G369 G373 V374 C375	L367-I371 HydrophobicContact CD1-CD1 4.21Å; L367-I371 HydrophobicContact CD1-CG1 4.49Å; L367-I371 HydrophobicContact CG-CD1 4.06Å; L367-I371 WeakPolarHBondContact O-CG1 3.48Å; L367-I371 PolarHBondContact O-N 2.88Å; V368-I371 PolarHBondContact O-N 3.02Å; G369-I371 PolarHBondContact O-N 2.73Å; I371-G373 VanDerWaalsContact C-N 3.33Å; I371-G373 PolarHBondContact O-N 2.98Å; I371-V374 PolarHBondContact O-N 3.32Å; I371-C375 WeakPolarHBondContact O-CB 3.12Å; I371-C375 PolarHBondContact O-N 3.12Å; I371-C375 PolarHBondContact O-SG 3.41Å
372	I	98.4	Very high	95.7	Very high	37 Å²	37	46.6 Å²	46.6	19%	0.19	23%	0.229	C	C	.	.	H	α-helix	trans	-59.5	-45	178.1	-66.4	169.9	0	0	0	110.7	V368 G369 I370 C375 A376 L395 I398 I402	V368-I372 HydrophobicContact CG1-CD1 3.75Å; V368-I372 HydrophobicContact CG1-CG1 4.41Å; V368-I372 VanDerWaalsContact O-CG1 3.3Å; V368-I372 WeakPolarHBondContact O-CG1 3.31Å; V368-I372 PolarHBondContact O-N 3.2Å; G369-I372 PolarHBondContact O-N 3.32Å; I370-I372 PolarHBondContact O-N 3.28Å; I372-C375 PolarHBondContact O-N 3.03Å; I372-A376 WeakPolarHBondContact O-CB 3.37Å; I372-A376 PolarHBondContact O-N 3.1Å; I372-L395 HydrophobicContact CG2-CB 3.98Å; I372-L395 HydrophobicContact CG2-CD2 4.1Å; I372-L395 WeakPolarHBondContact CG2-O 3.42Å; I372-I398 HydrophobicContact CD1-CG2 3.86Å; I372-I398 HydrophobicContact CG2-CG2 4.48Å; I372-I402 HydrophobicContact CD1-CD1 4.36Å
373	G	98.4	Very high	95.6	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-62.8	-45.5	179	0	0	0	0	0	113.2	G369 I370 I371 A376 S377 S399	G369-G373 PolarHBondContact O-N 3.29Å; I370-G373 PolarHBondContact O-N 2.89Å; I371-G373 VanDerWaalsContact C-N 3.33Å; I371-G373 PolarHBondContact O-N 2.98Å; G373-A376 PolarHBondContact O-N 3.43Å; G373-S377 WeakPolarHBondContact O-CB 3.49Å; G373-S377 PolarHBondContact O-N 2.95Å; G373-S377 PolarHBondContact O-OG 3Å; G373-S399 VanDerWaalsContact CA-OG 3.29Å; G373-S399 WeakPolarHBondContact CA-OG 3.43Å; G373-S399 PolarHBondContact N-OG 3.26Å
374	V	98.3	Very high	95.3	Very high	42 Å²	42	52 Å²	52	26%	0.255	26%	0.259	S	S	.	.	H	α-helix	trans	-64.7	-41.1	176.4	172.8	0	0	0	0	110.8	I370 I371 S377 G378 L475	I370-V374 HydrophobicContact CG2-CG2 4.35Å; I370-V374 WeakPolarHBondContact O-CG2 3.44Å; I370-V374 PolarHBondContact O-N 3.43Å; I371-V374 PolarHBondContact O-N 3.32Å; V374-S377 PolarHBondContact O-N 3.32Å; V374-G378 PolarHBondContact O-N 2.83Å; V374-L475 HydrophobicContact CG2-CB 3.78Å; V374-L475 HydrophobicContact CG2-CD1 3.99Å
375	C	98	Very high	95.1	Very high	75 Å²	75	48.3 Å²	48.3	51%	0.507	24%	0.239	S	C	.	.	H	α-helix	trans	-62.8	-42.8	174.5	-72.1	0	0	0	0	112	I371 I372 G378 W379	I371-C375 WeakPolarHBondContact O-CB 3.12Å; I371-C375 PolarHBondContact O-N 3.12Å; I371-C375 PolarHBondContact O-SG 3.41Å; I372-C375 PolarHBondContact O-N 3.03Å; C375-G378 PolarHBondContact O-N 3.4Å; C375-W379 WeakPolarHBondContact O-CB 3.42Å; C375-W379 PolarHBondContact O-N 3.45Å
376	A	98.2	Very high	95.1	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-63.1	-48.5	177.5	0	0	0	0	0	111.3	I372 G373 G378 W379 M380 L395 L396	I372-A376 WeakPolarHBondContact O-CB 3.37Å; I372-A376 PolarHBondContact O-N 3.1Å; G373-A376 PolarHBondContact O-N 3.43Å; A376-G378 VanDerWaalsContact C-N 3.32Å; A376-G378 PolarHBondContact O-N 2.95Å; A376-W379 WeakPolarHBondContact O-CB 3.2Å; A376-W379 PolarHBondContact O-N 3.08Å; A376-M380 WeakPolarHBondContact O-CG 3.25Å; A376-M380 PolarHBondContact O-N 3.19Å; A376-L395 HydrophobicContact CB-CB 3.73Å; A376-L396 HydrophobicContact CB-CD2 3.69Å; A376-L396 HydrophobicContact CB-CG 3.96Å
377	S	97.7	Very high	95	Very high	0 Å²	0	56.5 Å²	56.5	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-61.8	-38	174.5	-65.6	0	0	0	0	112.2	G373 V374 M380 V468 P471 S472	G373-S377 WeakPolarHBondContact O-CB 3.49Å; G373-S377 PolarHBondContact O-N 2.95Å; G373-S377 PolarHBondContact O-OG 3Å; V374-S377 PolarHBondContact O-N 3.32Å; S377-M380 WeakPolarHBondContact O-CB 3.41Å; S377-M380 PolarHBondContact O-N 3.25Å; S377-V468 VanDerWaalsContact O-CG2 3.31Å; S377-V468 WeakPolarHBondContact O-CG2 3.18Å; S377-P471 VanDerWaalsContact OG-CB 3.22Å; S377-P471 WeakPolarHBondContact OG-CB 3.4Å; S377-S472 WeakPolarHBondContact CB-OG 3.4Å
378	G	96.6	Very high	94.9	Very high	32 Å²	32	59.2 Å²	59.2	33%	0.33	30%	0.298	S	S	.	.	H	α-helix	trans	-64.9	-38.1	173.9	0	0	0	0	0	113.2	V374 C375 A376 M380 W381	V374-G378 PolarHBondContact O-N 2.83Å; C375-G378 PolarHBondContact O-N 3.4Å; A376-G378 VanDerWaalsContact C-N 3.32Å; A376-G378 PolarHBondContact O-N 2.95Å; G378-M380 PolarHBondContact O-N 2.86Å; G378-W381 WeakPolarHBondContact O-CB 3.39Å; G378-W381 PolarHBondContact O-N 3.47Å
379	W	97.1	Very high	95	Very high	89 Å²	89	56.1 Å²	56.1	34%	0.337	28%	0.279	S	S	.	.	H	α-helix	trans	-64.3	-29	175.4	-164.2	-9.8	0	0	0	111.7	C375 A376 W381 Y382 Q388 V392 L395	C375-W379 WeakPolarHBondContact O-CB 3.42Å; C375-W379 PolarHBondContact O-N 3.45Å; A376-W379 WeakPolarHBondContact O-CB 3.2Å; A376-W379 PolarHBondContact O-N 3.08Å; W379-W381 PolarHBondContact O-N 3.35Å; W379-Y382 AromaticContact CD1-CD2 3.77Å; W379-Y382 WeakPolarHBondContact O-CD2 3.39Å; W379-Y382 PolarHBondContact O-N 2.91Å; W379-Y382 VanDerWaalsContact O-N 3.1Å; W379-Q388 HydrophobicContact CZ2-CB 4.24Å; W379-V392 HydrophobicContact CB-CG2 3.97Å; W379-V392 HydrophobicContact CD2-CG2 3.72Å; W379-V392 HydrophobicContact CE3-CG2 4.01Å; W379-V392 HydrophobicContact CG-CG2 3.7Å; W379-L395 HydrophobicContact CE3-CD1 3.81Å; W379-L395 HydrophobicContact CZ3-CD1 3.81Å
380	M	95.7	Very high	95	Very high	0 Å²	0	58.6 Å²	58.6	0%	0	29%	0.289	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-5.9	172.6	-61	-176.8	77	0	0	113.9	L318 Y321 A376 S377 G378 Y382 V392 L396 M467 V468	L318-M380 HydrophobicContact CD1-CE 4.14Å; Y321-M380 HydrophobicContact CD1-CE 3.29Å; Y321-M380 HydrophobicContact CD2-CE 4.03Å; Y321-M380 HydrophobicContact CE1-CE 3.21Å; Y321-M380 HydrophobicContact CE2-CB 4.29Å; Y321-M380 HydrophobicContact CE2-CE 3.94Å; Y321-M380 HydrophobicContact CG-CE 3.71Å; Y321-M380 WeakPolarHBondContact OH-CA 3.27Å; Y321-M380 WeakPolarHBondContact OH-CB 3.42Å; Y321-M380 PolarHBondContact OH-O 2.92Å; A376-M380 WeakPolarHBondContact O-CG 3.25Å; A376-M380 PolarHBondContact O-N 3.19Å; S377-M380 WeakPolarHBondContact O-CB 3.41Å; S377-M380 PolarHBondContact O-N 3.25Å; G378-M380 PolarHBondContact O-N 2.86Å; M380-Y382 VanDerWaalsContact C-N 3.31Å; M380-V392 HydrophobicContact CG-CG1 3.52Å; M380-V392 HydrophobicContact SD-CG1 3.9Å; M380-L396 HydrophobicContact SD-CD1 4.26Å; M380-M467 HydrophobicContact CE-CB 3.73Å; M380-M467 HydrophobicContact CE-CE 3.5Å; M380-M467 VanDerWaalsContact CE-CE 3.5Å; M380-M467 HydrophobicContact CE-CG 3.92Å; M380-M467 HydrophobicContact SD-CB 4.07Å; M380-M467 HydrophobicContact SD-CE 3.88Å; M380-V468 HydrophobicContact CB-CG2 4.05Å
381	W	94.7	Very high	95	Very high	113 Å²	113	59.6 Å²	59.6	43%	0.428	30%	0.3	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.3	-15.2	171.1	-169.5	-95.7	0	0	0	113.7	G378 W379 K464 Y465 V468	G378-W381 WeakPolarHBondContact O-CB 3.39Å; G378-W381 PolarHBondContact O-N 3.47Å; W379-W381 PolarHBondContact O-N 3.35Å; W381-K464 VanDerWaalsContact CA-CE 3.45Å; W381-K464 HydrophobicContact CE3-CG 4.5Å; W381-K464 WeakPolarHBondContact O-CE 3.46Å; W381-K464 PolarHBondContact O-NZ 2.96Å; W381-Y465 HydrophobicContact CH2-CD1 4.28Å; W381-Y465 AromaticContact CH2-CE1 3.52Å; W381-Y465 HydrophobicContact CH2-CE1 3.52Å; W381-Y465 AromaticContact CH2-CZ 3.92Å; W381-Y465 AromaticContact CZ3-CD1 3.87Å; W381-Y465 HydrophobicContact CZ3-CD1 3.87Å; W381-Y465 AromaticContact CZ3-CE1 3.58Å; W381-Y465 HydrophobicContact CZ3-CE1 3.58Å; W381-V468 HydrophobicContact CB-CG2 4.27Å; W381-V468 HydrophobicContact CE3-CB 4.26Å; W381-V468 HydrophobicContact CE3-CG1 4.03Å; W381-V468 HydrophobicContact CE3-CG2 4.05Å
382	Y	91.9	Very high	94.9	Very high	151 Å²	151	55.1 Å²	55.1	59%	0.592	28%	0.278	S	S	*	.	S	Bend	trans	-76.2	144.4	176.6	-68.9	-86.3	0	0	0	111.4	Q326 W379 M380	Q326-Y382 PolarHBondContact NE2-O 2.91Å; W379-Y382 AromaticContact CD1-CD2 3.77Å; W379-Y382 WeakPolarHBondContact O-CD2 3.39Å; W379-Y382 PolarHBondContact O-N 2.91Å; W379-Y382 VanDerWaalsContact O-N 3.1Å; M380-Y382 VanDerWaalsContact C-N 3.31Å
383	H	84.3	Confident	94.9	Very high	117 Å²	117	53.4 Å²	53.4	54%	0.542	27%	0.269	S	S	.	.	S	Bend	trans	-82.5	145.3	174.8	-169	58.4	0	0	0	109.7	L385	H383-L385 PolarHBondContact O-N 2.92Å
384	E	84.9	Confident	94.9	Very high	137 Å²	137	57.2 Å²	57.2	64%	0.64	29%	0.288	S	S	*	.			trans	48	56.3	176.4	-67.2	178.6	175.5	0	0	114.3	G386	E384-G386 PolarHBondContact O-N 3.41Å; E384-G386 VanDerWaalsContact O-N 3.1Å
385	L	89.8	Confident	94.9	Very high	6 Å²	6	57.5 Å²	57.5	3%	0.031	29%	0.288	C	S	.	.			trans	-55.3	-28.8	176.9	-74	168.8	0	0	0	112.9	H383 M387 Q388 I389 V392	H383-L385 PolarHBondContact O-N 2.92Å; L385-M387 PolarHBondContact O-N 2.86Å; L385-M387 VanDerWaalsContact O-N 3.17Å; L385-Q388 HydrophobicContact CB-CB 4.22Å; L385-Q388 HydrophobicContact CD2-CB 4.06Å; L385-Q388 WeakPolarHBondContact O-CB 3.31Å; L385-Q388 WeakPolarHBondContact O-CG 3.33Å; L385-Q388 PolarHBondContact O-N 3.35Å; L385-I389 HydrophobicContact CB-CB 4.34Å; L385-V392 HydrophobicContact CD1-CG2 4.31Å
386	G	90.9	Very high	94.9	Very high	29 Å²	29	54.1 Å²	54.1	30%	0.299	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	54.3	-122.5	-175.7	0	0	0	0	0	110.8	E384 Q388 I389	E384-G386 PolarHBondContact O-N 3.41Å; E384-G386 VanDerWaalsContact O-N 3.1Å; G386-Q388 VanDerWaalsContact C-N 3.27Å; G386-Q388 PolarHBondContact O-N 2.88Å; G386-I389 WeakPolarHBondContact O-CG2 3.25Å; G386-I389 PolarHBondContact O-N 3.3Å
387	M	93.2	Very high	94.9	Very high	148 Å²	148	54.1 Å²	54.1	73%	0.729	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-17.3	178.2	-64.5	-61.1	-72.8	0	0	114.1	L385 I389 Y390	L385-M387 PolarHBondContact O-N 2.86Å; L385-M387 VanDerWaalsContact O-N 3.17Å; M387-I389 PolarHBondContact O-N 2.97Å; M387-Y390 HydrophobicContact CE-CD2 4.06Å; M387-Y390 HydrophobicContact CE-CE2 3.9Å; M387-Y390 WeakPolarHBondContact O-CD2 3.48Å; M387-Y390 PolarHBondContact O-N 3.5Å; M387-Y390 HydrophobicContact SD-CD2 4.25Å; M387-Y390 HydrophobicContact SD-CE2 3.87Å
388	Q	95.9	Very high	94.8	Very high	105 Å²	105	56.2 Å²	56.2	49%	0.491	28%	0.276	S	S	.	.	H	α-helix	trans	-64.9	-20.3	177.9	-59.5	-179.8	-3.9	0	0	112.4	W379 L385 G386 Y390 G391 V392	W379-Q388 HydrophobicContact CZ2-CB 4.24Å; L385-Q388 HydrophobicContact CB-CB 4.22Å; L385-Q388 HydrophobicContact CD2-CB 4.06Å; L385-Q388 WeakPolarHBondContact O-CB 3.31Å; L385-Q388 WeakPolarHBondContact O-CG 3.33Å; L385-Q388 PolarHBondContact O-N 3.35Å; G386-Q388 VanDerWaalsContact C-N 3.27Å; G386-Q388 PolarHBondContact O-N 2.88Å; Q388-Y390 PolarHBondContact O-N 3.08Å; Q388-G391 WeakPolarHBondContact O-CA 3.45Å; Q388-G391 PolarHBondContact O-N 3.18Å; Q388-V392 PolarHBondContact O-N 2.96Å; Q388-V392 VanDerWaalsContact O-N 3.16Å
389	I	96.6	Very high	94.9	Very high	0 Å²	0	54.7 Å²	54.7	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-59.9	-27.9	176.9	-158.9	167	0	0	0	112.8	Y321 I322 Q326 L328 V336 L385 G386 M387 G391 V392 A393	Y321-I389 HydrophobicContact CD1-CD1 4.38Å; Y321-I389 HydrophobicContact CE1-CD1 4.12Å; I322-I389 HydrophobicContact CD1-CD1 4.38Å; I322-I389 HydrophobicContact CG1-CD1 3.58Å; Q326-I389 HydrophobicContact CG-CD1 4.27Å; L328-I389 HydrophobicContact CD1-CD1 3.96Å; L328-I389 HydrophobicContact CD1-CG2 4.04Å; V336-I389 HydrophobicContact CG1-CD1 4.45Å; V336-I389 HydrophobicContact CG1-CG1 4.09Å; V336-I389 HydrophobicContact CG1-CG2 4.48Å; V336-I389 HydrophobicContact CG2-CG2 3.77Å; L385-I389 HydrophobicContact CB-CB 4.34Å; G386-I389 WeakPolarHBondContact O-CG2 3.25Å; G386-I389 PolarHBondContact O-N 3.3Å; M387-I389 PolarHBondContact O-N 2.97Å; I389-G391 VanDerWaalsContact C-N 3.34Å; I389-V392 WeakPolarHBondContact O-CB 3.33Å; I389-V392 PolarHBondContact O-N 3.22Å; I389-A393 WeakPolarHBondContact O-CB 3.42Å; I389-A393 PolarHBondContact O-N 3.16Å
390	Y	97.5	Very high	94.9	Very high	52 Å²	52	50.7 Å²	50.7	20%	0.204	25%	0.246	C	C	.	.	H	α-helix	trans	-68.7	-34.7	173.6	-68.5	-80.4	0	0	0	111.7	N332 T335 V336 A339 M387 Q388 A393 I394	N332-Y390 PolarHBondContact OD1-OH 2.9Å; N332-Y390 VanDerWaalsContact OD1-OH 3.1Å; T335-Y390 WeakPolarHBondContact CB-OH 3.28Å; T335-Y390 PolarHBondContact OG1-OH 2.91Å; V336-Y390 HydrophobicContact CG2-CD1 4.23Å; V336-Y390 HydrophobicContact CG2-CE1 3.82Å; V336-Y390 HydrophobicContact CG2-CE2 4.48Å; A339-Y390 HydrophobicContact CB-CD1 4.2Å; M387-Y390 HydrophobicContact CE-CD2 4.06Å; M387-Y390 HydrophobicContact CE-CE2 3.9Å; M387-Y390 WeakPolarHBondContact O-CD2 3.48Å; M387-Y390 PolarHBondContact O-N 3.5Å; M387-Y390 HydrophobicContact SD-CD2 4.25Å; M387-Y390 HydrophobicContact SD-CE2 3.87Å; Q388-Y390 PolarHBondContact O-N 3.08Å; Y390-A393 PolarHBondContact O-N 3.48Å; Y390-I394 WeakPolarHBondContact O-CD1 3.3Å; Y390-I394 VanDerWaalsContact O-CG1 3.26Å; Y390-I394 WeakPolarHBondContact O-CG1 3.32Å; Y390-I394 PolarHBondContact O-N 3.33Å
391	G	97.8	Very high	94.8	Very high	24 Å²	24	50.9 Å²	50.9	25%	0.247	25%	0.247	C	C	.	.	H	α-helix	trans	-63	-44.4	171.3	0	0	0	0	0	111.7	Q388 I389 A393 I394 L395	Q388-G391 WeakPolarHBondContact O-CA 3.45Å; Q388-G391 PolarHBondContact O-N 3.18Å; I389-G391 VanDerWaalsContact C-N 3.34Å; G391-A393 PolarHBondContact O-N 2.89Å; G391-I394 PolarHBondContact O-N 3.4Å; G391-L395 WeakPolarHBondContact O-CG 3.42Å; G391-L395 PolarHBondContact O-N 3.4Å; G391-L395 VanDerWaalsContact O-N 3.13Å
392	V	98	Very high	94.7	Very high	1 Å²	1	45.9 Å²	45.9	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-59.3	-47.3	173.1	177.8	0	0	0	0	111.1	W379 M380 L385 Q388 I389 I394 L395 L396	W379-V392 HydrophobicContact CB-CG2 3.97Å; W379-V392 HydrophobicContact CD2-CG2 3.72Å; W379-V392 HydrophobicContact CE3-CG2 4.01Å; W379-V392 HydrophobicContact CG-CG2 3.7Å; M380-V392 HydrophobicContact CG-CG1 3.52Å; M380-V392 HydrophobicContact SD-CG1 3.9Å; L385-V392 HydrophobicContact CD1-CG2 4.31Å; Q388-V392 PolarHBondContact O-N 2.96Å; Q388-V392 VanDerWaalsContact O-N 3.16Å; I389-V392 WeakPolarHBondContact O-CB 3.33Å; I389-V392 PolarHBondContact O-N 3.22Å; V392-I394 VanDerWaalsContact C-N 3.31Å; V392-I394 PolarHBondContact O-N 3.02Å; V392-L395 PolarHBondContact O-N 3.23Å; V392-L395 VanDerWaalsContact O-N 3.15Å; V392-L396 HydrophobicContact CG1-CD1 3.92Å; V392-L396 HydrophobicContact CG1-CG 4.2Å; V392-L396 WeakPolarHBondContact O-CG 3.46Å; V392-L396 PolarHBondContact O-N 2.99Å
393	A	98	Very high	94.9	Very high	1 Å²	1	38.7 Å²	38.7	1%	0.008	20%	0.201	C	C	.	.	H	α-helix	trans	-59	-41.4	179.4	0	0	0	0	0	112.7	V336 A339 V340 I389 Y390 G391 L396 G397	V336-A393 HydrophobicContact CG1-CB 3.74Å; A339-A393 HydrophobicContact CB-CB 4.02Å; V340-A393 WeakPolarHBondContact CA-O 3.37Å; V340-A393 HydrophobicContact CG2-CB 3.66Å; I389-A393 WeakPolarHBondContact O-CB 3.42Å; I389-A393 PolarHBondContact O-N 3.16Å; Y390-A393 PolarHBondContact O-N 3.48Å; G391-A393 PolarHBondContact O-N 2.89Å; A393-L396 PolarHBondContact O-N 2.77Å; A393-G397 PolarHBondContact O-N 3.44Å
394	I	98.4	Very high	95.3	Very high	79 Å²	79	35.4 Å²	35.4	41%	0.405	19%	0.187	S	C	.	.	H	α-helix	trans	-61.6	-45.6	175.4	-70.1	163.9	0	0	0	110.9	S343 Y390 G391 V392 G397 I398	S343-I394 PolarHBondContact OG-O 3.23Å; Y390-I394 WeakPolarHBondContact O-CD1 3.3Å; Y390-I394 VanDerWaalsContact O-CG1 3.26Å; Y390-I394 WeakPolarHBondContact O-CG1 3.32Å; Y390-I394 PolarHBondContact O-N 3.33Å; G391-I394 PolarHBondContact O-N 3.4Å; V392-I394 VanDerWaalsContact C-N 3.31Å; V392-I394 PolarHBondContact O-N 3.02Å; I394-G397 PolarHBondContact O-N 2.95Å; I394-I398 HydrophobicContact CG2-CD1 3.8Å; I394-I398 VanDerWaalsContact O-CG1 3.28Å; I394-I398 WeakPolarHBondContact O-CG1 3.44Å; I394-I398 PolarHBondContact O-N 3.04Å
395	L	98.4	Very high	95.6	Very high	49 Å²	49	31.3 Å²	31.3	26%	0.257	17%	0.169	S	C	.	.	H	α-helix	trans	-65.9	-39.8	177.9	-65.2	-179.7	0	0	0	112.4	I372 A376 W379 G391 V392 G397 I398 S399	I372-L395 HydrophobicContact CG2-CB 3.98Å; I372-L395 HydrophobicContact CG2-CD2 4.1Å; I372-L395 WeakPolarHBondContact CG2-O 3.42Å; A376-L395 HydrophobicContact CB-CB 3.73Å; W379-L395 HydrophobicContact CE3-CD1 3.81Å; W379-L395 HydrophobicContact CZ3-CD1 3.81Å; G391-L395 WeakPolarHBondContact O-CG 3.42Å; G391-L395 PolarHBondContact O-N 3.4Å; G391-L395 VanDerWaalsContact O-N 3.13Å; V392-L395 PolarHBondContact O-N 3.23Å; V392-L395 VanDerWaalsContact O-N 3.15Å; L395-G397 VanDerWaalsContact C-N 3.3Å; L395-G397 PolarHBondContact O-N 2.92Å; L395-I398 PolarHBondContact O-N 3.34Å; L395-S399 WeakPolarHBondContact O-CB 3.39Å; L395-S399 PolarHBondContact O-N 2.97Å
396	L	98	Very high	95.6	Very high	3 Å²	3	31.3 Å²	31.3	2%	0.016	17%	0.169	C	C	.	.	H	α-helix	trans	-59.7	-42.2	174.4	-71.4	172.9	0	0	0	111.1	F310 T314 V340 A376 M380 V392 A393 S399 A400	F310-L396 HydrophobicContact CE2-CD2 4.21Å; F310-L396 HydrophobicContact CZ-CD2 3.89Å; T314-L396 HydrophobicContact CG2-CD1 3.56Å; T314-L396 HydrophobicContact CG2-CD2 3.83Å; T314-L396 HydrophobicContact CG2-CG 4.15Å; V340-L396 HydrophobicContact CG1-CB 4.3Å; A376-L396 HydrophobicContact CB-CD2 3.69Å; A376-L396 HydrophobicContact CB-CG 3.96Å; M380-L396 HydrophobicContact SD-CD1 4.26Å; V392-L396 HydrophobicContact CG1-CD1 3.92Å; V392-L396 HydrophobicContact CG1-CG 4.2Å; V392-L396 WeakPolarHBondContact O-CG 3.46Å; V392-L396 PolarHBondContact O-N 2.99Å; A393-L396 PolarHBondContact O-N 2.77Å; L396-S399 PolarHBondContact O-N 3.42Å; L396-A400 WeakPolarHBondContact O-CB 3.3Å; L396-A400 PolarHBondContact O-N 2.82Å
397	G	96.8	Very high	95.7	Very high	0 Å²	0	30 Å²	30	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-69.2	-42	179.1	0	0	0	0	0	113	V340 S343 S344 A393 I394 L395 A400 A401	V340-G397 WeakPolarHBondContact O-CA 3.38Å; S343-G397 WeakPolarHBondContact OG-CA 3.34Å; S344-G397 WeakPolarHBondContact CA-O 3.45Å; S344-G397 WeakPolarHBondContact OG-CA 3.38Å; S344-G397 PolarHBondContact OG-O 3.25Å; S344-G397 VanDerWaalsContact OG-O 3.09Å; A393-G397 PolarHBondContact O-N 3.44Å; I394-G397 PolarHBondContact O-N 2.95Å; L395-G397 VanDerWaalsContact C-N 3.3Å; L395-G397 PolarHBondContact O-N 2.92Å; G397-A400 PolarHBondContact O-N 3.03Å; G397-A401 WeakPolarHBondContact O-CB 3.42Å; G397-A401 PolarHBondContact O-N 2.99Å
398	I	97.3	Very high	95.5	Very high	44 Å²	44	26.1 Å²	26.1	23%	0.226	14%	0.137	C	C	.	.	H	α-helix	trans	-58.6	-50.5	173.1	-66.9	164.3	0	0	0	110.3	T347 I372 I394 L395 I402	T347-I398 HydrophobicContact CG2-CG2 4.24Å; T347-I398 WeakPolarHBondContact OG1-CG1 3.2Å; I372-I398 HydrophobicContact CD1-CG2 3.86Å; I372-I398 HydrophobicContact CG2-CG2 4.48Å; I394-I398 HydrophobicContact CG2-CD1 3.8Å; I394-I398 VanDerWaalsContact O-CG1 3.28Å; I394-I398 WeakPolarHBondContact O-CG1 3.44Å; I394-I398 PolarHBondContact O-N 3.04Å; L395-I398 PolarHBondContact O-N 3.34Å; I398-I402 HydrophobicContact CG2-CD1 3.71Å; I398-I402 VanDerWaalsContact O-CG1 3.24Å; I398-I402 WeakPolarHBondContact O-CG1 3.4Å; I398-I402 PolarHBondContact O-N 3.26Å; I398-I402 VanDerWaalsContact O-N 3.1Å
399	S	98.1	Very high	95.1	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-57.7	-52.4	177.7	173.6	0	0	0	0	111.8	G369 G373 L395 L396 A401 I402 L403	G369-S399 PolarHBondContact O-OG 3.26Å; G373-S399 VanDerWaalsContact CA-OG 3.29Å; G373-S399 WeakPolarHBondContact CA-OG 3.43Å; G373-S399 PolarHBondContact N-OG 3.26Å; L395-S399 WeakPolarHBondContact O-CB 3.39Å; L395-S399 PolarHBondContact O-N 2.97Å; L396-S399 PolarHBondContact O-N 3.42Å; S399-A401 PolarHBondContact O-N 3.29Å; S399-I402 PolarHBondContact O-N 3.37Å; S399-L403 WeakPolarHBondContact O-CB 3.27Å; S399-L403 VanDerWaalsContact O-CG 3.24Å; S399-L403 WeakPolarHBondContact O-CG 3.41Å; S399-L403 PolarHBondContact O-N 2.85Å; S399-L403 WeakPolarHBondContact OG-CD1 3.49Å
400	A	96.1	Very high	94.8	Very high	6 Å²	6	22.5 Å²	22.5	5%	0.05	12%	0.124	C	C	.	.	H	α-helix	trans	-55.5	-48.5	-178.4	0	0	0	0	0	112	N311 L396 G397 L403 I404	N311-A400 VanDerWaalsContact OD1-CA 3.26Å; N311-A400 WeakPolarHBondContact OD1-CA 3.37Å; N311-A400 WeakPolarHBondContact OD1-CB 3.49Å; L396-A400 WeakPolarHBondContact O-CB 3.3Å; L396-A400 PolarHBondContact O-N 2.82Å; G397-A400 PolarHBondContact O-N 3.03Å; A400-L403 PolarHBondContact O-N 2.98Å; A400-I404 WeakPolarHBondContact O-CB 3.41Å; A400-I404 VanDerWaalsContact O-CG1 3.25Å; A400-I404 WeakPolarHBondContact O-CG1 3.23Å; A400-I404 PolarHBondContact O-N 3.04Å
401	A	93.6	Very high	94.3	Very high	3 Å²	3	20 Å²	20	3%	0.025	11%	0.114	C	C	.	.	H	α-helix	trans	-62.9	-49.9	179.5	0	0	0	0	0	112.1	S344 T347 G397 S399 L403 I404 I405	S344-A401 WeakPolarHBondContact O-CB 3.43Å; T347-A401 HydrophobicContact CG2-CB 3.86Å; G397-A401 WeakPolarHBondContact O-CB 3.42Å; G397-A401 PolarHBondContact O-N 2.99Å; S399-A401 PolarHBondContact O-N 3.29Å; A401-L403 VanDerWaalsContact C-N 3.3Å; A401-L403 PolarHBondContact O-N 3.22Å; A401-I404 PolarHBondContact O-N 3.26Å; A401-I405 WeakPolarHBondContact O-CB 3.49Å; A401-I405 WeakPolarHBondContact O-CD1 3.29Å; A401-I405 WeakPolarHBondContact O-CG1 3.49Å; A401-I405 PolarHBondContact O-N 3.36Å
402	I	93.8	Very high	93.7	Very high	8 Å²	8	21.3 Å²	21.3	4%	0.041	12%	0.123	C	C	.	.	H	α-helix	trans	-57	-46.6	179.2	-68.5	172.8	0	0	0	110.5	T347 F351 S365 I372 I398 S399 N406	T347-I402 HydrophobicContact CG2-CD1 4.27Å; T347-I402 HydrophobicContact CG2-CG1 3.7Å; F351-I402 HydrophobicContact CD2-CG1 4.36Å; F351-I402 HydrophobicContact CE2-CD1 4.06Å; F351-I402 HydrophobicContact CE2-CG1 3.61Å; F351-I402 HydrophobicContact CZ-CD1 4.2Å; F351-I402 HydrophobicContact CZ-CG1 3.78Å; F351-I402 HydrophobicContact CZ-CG2 4.22Å; S365-I402 WeakPolarHBondContact O-CG2 3.33Å; I372-I402 HydrophobicContact CD1-CD1 4.36Å; I398-I402 HydrophobicContact CG2-CD1 3.71Å; I398-I402 VanDerWaalsContact O-CG1 3.24Å; I398-I402 WeakPolarHBondContact O-CG1 3.4Å; I398-I402 PolarHBondContact O-N 3.26Å; I398-I402 VanDerWaalsContact O-N 3.1Å; S399-I402 PolarHBondContact O-N 3.37Å; I402-N406 WeakPolarHBondContact O-CB 3.02Å; I402-N406 PolarHBondContact O-N 3.33Å; I402-N406 VanDerWaalsContact O-N 3.11Å; I402-N406 PolarHBondContact O-ND2 2.77Å
403	L	95.9	Very high	93.1	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-71.4	-44.2	-175	-67.5	175.3	0	0	0	112.3	I307 F310 S366 I370 S399 A400 A401 N406 A407 L475	I307-L403 HydrophobicContact CB-CB 4.48Å; I307-L403 HydrophobicContact CD1-CB 3.94Å; I307-L403 HydrophobicContact CD1-CD2 4.09Å; I307-L403 HydrophobicContact CG1-CB 4.07Å; I307-L403 HydrophobicContact CG1-CD1 4.43Å; I307-L403 HydrophobicContact CG1-CD2 4.42Å; I307-L403 HydrophobicContact CG2-CB 3.61Å; F310-L403 HydrophobicContact CD1-CD1 4.4Å; F310-L403 HydrophobicContact CE1-CD1 4.5Å; S366-L403 WeakPolarHBondContact O-CD2 3.07Å; I370-L403 HydrophobicContact CG1-CD2 3.87Å; S399-L403 WeakPolarHBondContact O-CB 3.27Å; S399-L403 VanDerWaalsContact O-CG 3.24Å; S399-L403 WeakPolarHBondContact O-CG 3.41Å; S399-L403 PolarHBondContact O-N 2.85Å; S399-L403 WeakPolarHBondContact OG-CD1 3.49Å; A400-L403 PolarHBondContact O-N 2.98Å; A401-L403 VanDerWaalsContact C-N 3.3Å; A401-L403 PolarHBondContact O-N 3.22Å; L403-N406 PolarHBondContact O-N 2.88Å; L403-A407 WeakPolarHBondContact O-CB 3.09Å; L403-A407 PolarHBondContact O-N 3.07Å; L403-L475 HydrophobicContact CD1-CD2 3.54Å
404	I	93	Very high	92.5	Very high	48 Å²	48	24.1 Å²	24.1	25%	0.246	14%	0.138	C	C	.	.	H	α-helix	trans	-63	-46.4	178.4	-69.7	170	0	0	0	110.7	I307 N311 A400 A401 N406 A407 L408	I307-I404 HydrophobicContact CG2-CG1 4.3Å; N311-I404 WeakPolarHBondContact ND2-CD1 3.38Å; N311-I404 VanDerWaalsContact ND2-CG1 3.26Å; N311-I404 WeakPolarHBondContact ND2-CG1 3.36Å; A400-I404 WeakPolarHBondContact O-CB 3.41Å; A400-I404 VanDerWaalsContact O-CG1 3.25Å; A400-I404 WeakPolarHBondContact O-CG1 3.23Å; A400-I404 PolarHBondContact O-N 3.04Å; A401-I404 PolarHBondContact O-N 3.26Å; I404-N406 PolarHBondContact O-N 2.8Å; I404-A407 PolarHBondContact O-N 3.2Å; I404-L408 HydrophobicContact CG2-CD1 3.92Å; I404-L408 HydrophobicContact CG2-CG 4.48Å; I404-L408 WeakPolarHBondContact O-CB 3.17Å; I404-L408 WeakPolarHBondContact O-CG 3.38Å; I404-L408 PolarHBondContact O-N 3.16Å
405	I	89.3	Confident	91.7	Very high	52 Å²	52	21 Å²	21	27%	0.267	12%	0.121	S	C	.	.	H	α-helix	trans	-60.1	-48.8	-179.7	-69.1	167.9	0	0	0	110.1	F351 A401 A409	F351-I405 HydrophobicContact CB-CD1 4.12Å; A401-I405 WeakPolarHBondContact O-CB 3.49Å; A401-I405 WeakPolarHBondContact O-CD1 3.29Å; A401-I405 WeakPolarHBondContact O-CG1 3.49Å; A401-I405 PolarHBondContact O-N 3.36Å; I405-A409 VanDerWaalsContact O-CB 3.28Å; I405-A409 WeakPolarHBondContact O-CB 3.38Å; I405-A409 PolarHBondContact O-N 3.19Å
406	N	91.5	Very high	90.8	Very high	6 Å²	6	23 Å²	23	3%	0.032	13%	0.133	C	C	.	.	H	α-helix	trans	-70.4	-35.7	-179.1	-73.3	-57	0	0	0	113	S365 S366 I402 L403 I404 A409 L410	S365-N406 WeakPolarHBondContact CB-ND2 3.08Å; S365-N406 VanDerWaalsContact OG-CG 3.31Å; S365-N406 PolarHBondContact OG-ND2 3.16Å; S365-N406 PolarHBondContact OG-OD1 2.98Å; S365-N406 VanDerWaalsContact OG-OD1 3.09Å; S366-N406 WeakPolarHBondContact OG-CB 3.09Å; I402-N406 WeakPolarHBondContact O-CB 3.02Å; I402-N406 PolarHBondContact O-N 3.33Å; I402-N406 VanDerWaalsContact O-N 3.11Å; I402-N406 PolarHBondContact O-ND2 2.77Å; L403-N406 PolarHBondContact O-N 2.88Å; I404-N406 PolarHBondContact O-N 2.8Å; N406-A409 PolarHBondContact O-N 3.12Å; N406-L410 WeakPolarHBondContact O-CB 3.37Å; N406-L410 VanDerWaalsContact O-CG 3.27Å; N406-L410 WeakPolarHBondContact O-CG 3.46Å; N406-L410 PolarHBondContact O-N 3.05Å
407	A	93	Very high	89.4	Confident	1 Å²	1	31.4 Å²	31.4	1%	0.008	17%	0.169	C	C	.	.	H	α-helix	trans	-62.9	-47.2	176.1	0	0	0	0	0	111.2	F303 Y304 I307 L403 I404 A409 L410 T411	F303-A407 HydrophobicContact CD1-CB 4.33Å; F303-A407 HydrophobicContact CE1-CB 4.15Å; Y304-A407 HydrophobicContact CD2-CB 4.01Å; I307-A407 HydrophobicContact CD1-CB 3.89Å; L403-A407 WeakPolarHBondContact O-CB 3.09Å; L403-A407 PolarHBondContact O-N 3.07Å; I404-A407 PolarHBondContact O-N 3.2Å; A407-A409 VanDerWaalsContact C-N 3.32Å; A407-A409 PolarHBondContact O-N 3.5Å; A407-L410 PolarHBondContact O-N 3.4Å; A407-T411 PolarHBondContact O-N 3.43Å; A407-T411 PolarHBondContact O-OG1 3.02Å; A407-T411 VanDerWaalsContact O-OG1 3.1Å
408	L	89.1	Confident	88.2	Confident	67 Å²	67	32.8 Å²	32.8	35%	0.351	18%	0.179	S	C	.	.	H	α-helix	trans	-62.2	-40.5	175.4	-70.8	172.5	0	0	0	111.9	Y304 I404 T411 A412 F426	Y304-L408 HydrophobicContact CE2-CD2 3.92Å; I404-L408 HydrophobicContact CG2-CD1 3.92Å; I404-L408 HydrophobicContact CG2-CG 4.48Å; I404-L408 WeakPolarHBondContact O-CB 3.17Å; I404-L408 WeakPolarHBondContact O-CG 3.38Å; I404-L408 PolarHBondContact O-N 3.16Å; L408-T411 PolarHBondContact O-N 3.24Å; L408-A412 PolarHBondContact O-N 2.77Å; L408-F426 HydrophobicContact CD2-CE1 4.42Å
409	A	86.7	Confident	86.8	Confident	24 Å²	24	35.5 Å²	35.5	20%	0.198	20%	0.198	C	C	.	.	H	α-helix	trans	-64.3	-43.2	177.5	0	0	0	0	0	111.7	R362 I405 N406 A407 T411 A412 D413	R362-A409 PolarHBondContact NH1-O 2.79Å; I405-A409 VanDerWaalsContact O-CB 3.28Å; I405-A409 WeakPolarHBondContact O-CB 3.38Å; I405-A409 PolarHBondContact O-N 3.19Å; N406-A409 PolarHBondContact O-N 3.12Å; A407-A409 VanDerWaalsContact C-N 3.32Å; A407-A409 PolarHBondContact O-N 3.5Å; A409-T411 VanDerWaalsContact C-N 3.35Å; A409-A412 PolarHBondContact O-N 3.31Å; A409-D413 PolarHBondContact O-N 3Å
410	L	89.9	Confident	85.2	Confident	4 Å²	4	41.6 Å²	41.6	2%	0.021	23%	0.226	C	C	.	.	H	α-helix	trans	-63.8	-38.6	175	-73.6	169.8	0	0	0	112.1	I300 F303 N406 A407 D413 L414 V490	I300-L410 HydrophobicContact CG2-CB 4.32Å; F303-L410 HydrophobicContact CD1-CD1 4.04Å; F303-L410 HydrophobicContact CE1-CD1 3.7Å; F303-L410 HydrophobicContact CZ-CD1 4.47Å; N406-L410 WeakPolarHBondContact O-CB 3.37Å; N406-L410 VanDerWaalsContact O-CG 3.27Å; N406-L410 WeakPolarHBondContact O-CG 3.46Å; N406-L410 PolarHBondContact O-N 3.05Å; A407-L410 PolarHBondContact O-N 3.4Å; L410-D413 PolarHBondContact O-N 2.88Å; L410-L414 WeakPolarHBondContact O-CB 3.41Å; L410-L414 PolarHBondContact O-N 3.33Å; L410-V490 HydrophobicContact CD2-CG2 4.16Å
411	T	88.5	Confident	84	Confident	0 Å²	0	41.8 Å²	41.8	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-63.5	-42	173	-60	0	0	0	0	111.7	A407 L408 A409 L414 I415 V425 F426 M429	A407-T411 PolarHBondContact O-N 3.43Å; A407-T411 PolarHBondContact O-OG1 3.02Å; A407-T411 VanDerWaalsContact O-OG1 3.1Å; L408-T411 PolarHBondContact O-N 3.24Å; A409-T411 VanDerWaalsContact C-N 3.35Å; T411-L414 WeakPolarHBondContact O-CB 3.4Å; T411-L414 PolarHBondContact O-N 3.43Å; T411-I415 HydrophobicContact CG2-CD1 4.19Å; T411-I415 WeakPolarHBondContact O-CG1 3.38Å; T411-I415 PolarHBondContact O-N 2.83Å; T411-I415 VanDerWaalsContact O-N 3.1Å; T411-V425 HydrophobicContact CG2-CG1 4.14Å; T411-F426 HydrophobicContact CG2-CD1 3.89Å; T411-F426 HydrophobicContact CG2-CE1 3.43Å; T411-F426 VanDerWaalsContact CG2-CE1 3.43Å; T411-F426 HydrophobicContact CG2-CE2 4.39Å; T411-F426 HydrophobicContact CG2-CZ 3.72Å; T411-M429 HydrophobicContact CG2-CE 3.88Å; T411-M429 HydrophobicContact CG2-SD 3.52Å; T411-M429 VanDerWaalsContact CG2-SD 3.52Å
412	A	83.9	Confident	83	Confident	51 Å²	51	41.9 Å²	41.9	42%	0.421	23%	0.228	S	C	.	.	H	α-helix	trans	-64.1	-40.3	175.4	0	0	0	0	0	112.2	L408 A409 L414 I415 N416	L408-A412 PolarHBondContact O-N 2.77Å; A409-A412 PolarHBondContact O-N 3.31Å; A412-L414 VanDerWaalsContact C-N 3.33Å; A412-I415 PolarHBondContact O-N 2.93Å; A412-N416 PolarHBondContact O-N 3.47Å
413	D	85.1	Confident	82	Confident	54 Å²	54	45.1 Å²	45.1	29%	0.289	26%	0.256	S	S	.	.	H	α-helix	trans	-66.4	-33.1	174.4	-75.2	1	0	0	0	112.6	R362 A409 L410 N416 V490 G491	R362-D413 IonicContact CZ-OD1 2.61Å; R362-D413 VanDerWaalsContact CZ-OD1 3.3Å; R362-D413 IonicContact CZ-OD2 2.66Å; R362-D413 IonicContact NE-OD2 2.74Å; R362-D413 IonicContact NH1-OD1 2.62Å; R362-D413 PolarHBondContact NH1-OD1 3.37Å; R362-D413 IonicContact NH1-OD2 3.38Å; R362-D413 PolarHBondContact NH1-OD2 3.4Å; R362-D413 IonicContact NH2-OD1 3.99Å; R362-D413 PolarHBondContact NH2-OD1 2.8Å; R362-D413 IonicContact NH2-OD2 3.38Å; A409-D413 PolarHBondContact O-N 3Å; L410-D413 PolarHBondContact O-N 2.88Å; D413-N416 WeakPolarHBondContact O-CB 3.35Å; D413-V490 HydrophobicContact CB-CB 4.37Å; D413-V490 HydrophobicContact CB-CG1 3.69Å; D413-G491 WeakPolarHBondContact O-CA 3.44Å
414	L	85.9	Confident	81.3	Confident	7 Å²	7	48.4 Å²	48.4	4%	0.037	27%	0.271	C	S	.	.	H	α-helix	trans	-64.5	-43.9	174.2	173.7	64.9	0	0	0	111	W291 Q296 F297 I300 L410 T411 A412 V425 M429 V490	W291-L414 HydrophobicContact CH2-CG 4.48Å; W291-L414 HydrophobicContact CZ3-CD1 3.96Å; W291-L414 HydrophobicContact CZ3-CD2 4.4Å; W291-L414 HydrophobicContact CZ3-CG 3.86Å; Q296-L414 HydrophobicContact CB-CD1 3.84Å; F297-L414 HydrophobicContact CB-CD2 4.28Å; F297-L414 HydrophobicContact CD2-CD2 4.2Å; I300-L414 HydrophobicContact CB-CD2 4.2Å; I300-L414 HydrophobicContact CD1-CB 3.79Å; I300-L414 HydrophobicContact CD1-CD1 4.15Å; I300-L414 HydrophobicContact CD1-CD2 4.18Å; I300-L414 HydrophobicContact CD1-CG 4.25Å; I300-L414 HydrophobicContact CG2-CD2 4.3Å; L410-L414 WeakPolarHBondContact O-CB 3.41Å; L410-L414 PolarHBondContact O-N 3.33Å; T411-L414 WeakPolarHBondContact O-CB 3.4Å; T411-L414 PolarHBondContact O-N 3.43Å; A412-L414 VanDerWaalsContact C-N 3.33Å; L414-V425 HydrophobicContact CD2-CG1 4.26Å; L414-M429 HydrophobicContact CD2-CE 4.05Å; L414-V490 HydrophobicContact CB-CG1 4.42Å
415	I	81.4	Confident	80.9	Confident	13 Å²	13	46.1 Å²	46.1	7%	0.067	26%	0.259	C	S	.	.	H	α-helix	trans	-66.8	-42.6	179.2	-65.9	165.9	0	0	0	110.1	T411 A412 K417 S418 V425 F426	T411-I415 HydrophobicContact CG2-CD1 4.19Å; T411-I415 WeakPolarHBondContact O-CG1 3.38Å; T411-I415 PolarHBondContact O-N 2.83Å; T411-I415 VanDerWaalsContact O-N 3.1Å; A412-I415 PolarHBondContact O-N 2.93Å; I415-K417 PolarHBondContact O-N 2.98Å; I415-S418 WeakPolarHBondContact O-CA 3.42Å; I415-S418 WeakPolarHBondContact O-CB 3.41Å; I415-S418 PolarHBondContact O-N 3.29Å; I415-V425 HydrophobicContact CD1-CB 4.19Å; I415-V425 HydrophobicContact CD1-CG1 4.22Å; I415-V425 HydrophobicContact CG1-CB 4.15Å; I415-V425 HydrophobicContact CG1-CG1 4.12Å; I415-V425 HydrophobicContact CG1-CG2 4.32Å; I415-F426 HydrophobicContact CD1-CD2 3.59Å; I415-F426 HydrophobicContact CD1-CE2 3.22Å; I415-F426 HydrophobicContact CD1-CZ 3.92Å
416	N	79.2	Confident	80.6	Confident	92 Å²	92	47.4 Å²	47.4	49%	0.492	26%	0.263	S	S	.	.	T	Hydrogen-bonded Turn	trans	43.8	-109	177.6	-166.4	1	0	0	0	113.1	A412 D413 G491	A412-N416 PolarHBondContact O-N 3.47Å; D413-N416 WeakPolarHBondContact O-CB 3.35Å; N416-G491 PolarHBondContact ND2-O 3.23Å
417	K	69.9	Low	80.2	Confident	180 Å²	180	48 Å²	48	78%	0.783	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.1	-14.3	-179.5	-64.6	-175.4	178.8	-178.2	0	113.6	I415 T419	I415-K417 PolarHBondContact O-N 2.98Å; K417-T419 PolarHBondContact O-N 3.45Å
418	S	70.4	Confident	79.9	Confident	29 Å²	29	48.7 Å²	48.7	20%	0.203	28%	0.276	C	S	.	.			trans	-82.7	47.5	-178	-54.1	0	0	0	0	111.8	I415 E420 S421 G422	I415-S418 WeakPolarHBondContact O-CA 3.42Å; I415-S418 WeakPolarHBondContact O-CB 3.41Å; I415-S418 PolarHBondContact O-N 3.29Å; S418-E420 PolarHBondContact O-N 2.89Å; S418-S421 PolarHBondContact O-N 2.79Å; S418-G422 PolarHBondContact O-N 3.04Å
419	T	67.8	Low	79.9	Confident	101 Å²	101	45.5 Å²	45.5	62%	0.62	26%	0.259	S	S	*	.	G	3₁₀ helix	trans	-64.9	-27.9	-171.3	51.2	0	0	0	0	113.3	K417 S421 G422	K417-T419 PolarHBondContact O-N 3.45Å; T419-S421 VanDerWaalsContact C-N 3.29Å; T419-S421 PolarHBondContact O-N 3.38Å; T419-G422 PolarHBondContact O-N 2.94Å
420	E	65.7	Low	79.9	Confident	127 Å²	127	45.4 Å²	45.4	59%	0.593	26%	0.257	S	S	*	.	G	3₁₀ helix	trans	-63.2	-33.1	-178.7	-61.9	-172.1	170.3	0	0	113.2	S418	S418-E420 PolarHBondContact O-N 2.89Å
421	S	71.1	Confident	79.9	Confident	11 Å²	11	48.7 Å²	48.7	8%	0.077	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-108.6	9.4	175.9	53	0	0	0	0	113.8	V286 W291 S418 T419 A423 F424 V425	V286-S421 WeakPolarHBondContact CB-OG 3.4Å; V286-S421 WeakPolarHBondContact CG1-OG 3.35Å; V286-S421 WeakPolarHBondContact O-CB 3.43Å; V286-S421 PolarHBondContact O-OG 2.98Å; W291-S421 VanDerWaalsContact NE1-CB 3.28Å; W291-S421 PolarHBondContact NE1-OG 2.92Å; S418-S421 PolarHBondContact O-N 2.79Å; T419-S421 VanDerWaalsContact C-N 3.29Å; T419-S421 PolarHBondContact O-N 3.38Å; S421-A423 PolarHBondContact O-N 3.25Å; S421-F424 WeakPolarHBondContact O-CB 3.28Å; S421-F424 PolarHBondContact O-N 3.37Å; S421-F424 VanDerWaalsContact O-N 3.16Å; S421-V425 PolarHBondContact O-N 3.01Å
422	G	71.7	Confident	80	Confident	5 Å²	5	54 Å²	54	5%	0.052	29%	0.294	C	S	.	.	H	α-helix	trans	-61.6	-31.2	173.6	0	0	0	0	0	113.1	S418 T419 F424 V425 F426	S418-G422 PolarHBondContact O-N 3.04Å; T419-G422 PolarHBondContact O-N 2.94Å; G422-F424 VanDerWaalsContact C-N 3.32Å; G422-F424 PolarHBondContact O-N 2.86Å; G422-V425 WeakPolarHBondContact O-CB 3.47Å; G422-V425 PolarHBondContact O-N 3.35Å; G422-F426 WeakPolarHBondContact O-CD2 3.26Å; G422-F426 PolarHBondContact O-N 3.26Å
423	A	73.8	Confident	80.4	Confident	76 Å²	76	51.8 Å²	51.8	63%	0.628	28%	0.276	S	S	*	.	H	α-helix	trans	-61.3	-39.1	174.5	0	0	0	0	0	112.3	S421 G427	S421-A423 PolarHBondContact O-N 3.25Å; A423-G427 PolarHBondContact O-N 2.93Å
424	F	81	Confident	80.8	Confident	69 Å²	69	50.2 Å²	50.2	30%	0.303	27%	0.266	S	S	.	.	H	α-helix	trans	-62.9	-42.6	174.3	171.3	-97.8	0	0	0	111.4	W288 W291 L292 F297 S421 G422 G427 A428	W288-F424 HydrophobicContact CB-CD1 4Å; W288-F424 HydrophobicContact CB-CD2 3.81Å; W288-F424 HydrophobicContact CB-CE1 4.12Å; W288-F424 HydrophobicContact CB-CE2 3.94Å; W288-F424 HydrophobicContact CB-CG 3.84Å; W288-F424 HydrophobicContact CB-CZ 4.09Å; W288-F424 HydrophobicContact CE3-CE2 4.46Å; W288-F424 HydrophobicContact CE3-CZ 4.33Å; W291-F424 HydrophobicContact CB-CD1 4.17Å; W291-F424 HydrophobicContact CB-CE1 3.94Å; W291-F424 AromaticContact CD1-CD1 3.8Å; W291-F424 HydrophobicContact CG-CD1 4.2Å; W291-F424 HydrophobicContact CG-CE1 4.46Å; L292-F424 HydrophobicContact CD2-CZ 4.3Å; F297-F424 HydrophobicContact CZ-CE1 4.37Å; S421-F424 WeakPolarHBondContact O-CB 3.28Å; S421-F424 PolarHBondContact O-N 3.37Å; S421-F424 VanDerWaalsContact O-N 3.16Å; G422-F424 VanDerWaalsContact C-N 3.32Å; G422-F424 PolarHBondContact O-N 2.86Å; F424-G427 PolarHBondContact O-N 3.21Å; F424-A428 HydrophobicContact CZ-CB 4.45Å; F424-A428 VanDerWaalsContact O-CB 3.29Å; F424-A428 WeakPolarHBondContact O-CB 3.32Å; F424-A428 PolarHBondContact O-N 3.42Å
425	V	83.9	Confident	81.2	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-60.5	-52.2	179.2	175.9	0	0	0	0	110.8	W291 F297 T411 L414 I415 S421 G422 G427 A428 M429	W291-V425 HydrophobicContact CD2-CG2 3.49Å; W291-V425 VanDerWaalsContact CD2-CG2 3.49Å; W291-V425 VanDerWaalsContact CE2-CG2 3.45Å; W291-V425 HydrophobicContact CE3-CG2 3.91Å; W291-V425 HydrophobicContact CG-CG2 3.88Å; W291-V425 HydrophobicContact CH2-CG2 4.25Å; W291-V425 HydrophobicContact CZ2-CG2 3.84Å; W291-V425 HydrophobicContact CZ3-CG2 4.27Å; F297-V425 HydrophobicContact CD2-CG1 4.09Å; F297-V425 HydrophobicContact CD2-CG2 4.18Å; F297-V425 HydrophobicContact CE2-CB 4.25Å; F297-V425 HydrophobicContact CE2-CG1 3.94Å; F297-V425 HydrophobicContact CE2-CG2 4.08Å; T411-V425 HydrophobicContact CG2-CG1 4.14Å; L414-V425 HydrophobicContact CD2-CG1 4.26Å; I415-V425 HydrophobicContact CD1-CB 4.19Å; I415-V425 HydrophobicContact CD1-CG1 4.22Å; I415-V425 HydrophobicContact CG1-CB 4.15Å; I415-V425 HydrophobicContact CG1-CG1 4.12Å; I415-V425 HydrophobicContact CG1-CG2 4.32Å; S421-V425 PolarHBondContact O-N 3.01Å; G422-V425 WeakPolarHBondContact O-CB 3.47Å; G422-V425 PolarHBondContact O-N 3.35Å; V425-G427 PolarHBondContact O-N 3.43Å; V425-A428 PolarHBondContact O-N 3.41Å; V425-M429 HydrophobicContact CG1-CE 3.44Å; V425-M429 VanDerWaalsContact CG1-CE 3.44Å; V425-M429 HydrophobicContact CG1-SD 4.02Å; V425-M429 WeakPolarHBondContact O-CB 3.35Å; V425-M429 VanDerWaalsContact O-CG 3.25Å; V425-M429 WeakPolarHBondContact O-CG 3.12Å; V425-M429 PolarHBondContact O-N 3.35Å
426	F	82.8	Confident	81.8	Confident	78 Å²	78	54.8 Å²	54.8	34%	0.342	29%	0.29	S	S	.	.	H	α-helix	trans	-62.8	-40.9	177	-79.4	-67.3	0	0	0	112.4	L408 T411 I415 G422 S430	L408-F426 HydrophobicContact CD2-CE1 4.42Å; T411-F426 HydrophobicContact CG2-CD1 3.89Å; T411-F426 HydrophobicContact CG2-CE1 3.43Å; T411-F426 VanDerWaalsContact CG2-CE1 3.43Å; T411-F426 HydrophobicContact CG2-CE2 4.39Å; T411-F426 HydrophobicContact CG2-CZ 3.72Å; I415-F426 HydrophobicContact CD1-CD2 3.59Å; I415-F426 HydrophobicContact CD1-CE2 3.22Å; I415-F426 HydrophobicContact CD1-CZ 3.92Å; G422-F426 WeakPolarHBondContact O-CD2 3.26Å; G422-F426 PolarHBondContact O-N 3.26Å; F426-S430 WeakPolarHBondContact O-CB 3.42Å; F426-S430 PolarHBondContact O-N 3.05Å; F426-S430 PolarHBondContact O-OG 3.42Å
427	G	83.7	Confident	82.6	Confident	18 Å²	18	50.4 Å²	50.4	19%	0.186	27%	0.266	C	S	.	.	H	α-helix	trans	-62.9	-47.3	178.1	0	0	0	0	0	112.7	A423 F424 V425 S430 F431	A423-G427 PolarHBondContact O-N 2.93Å; F424-G427 PolarHBondContact O-N 3.21Å; V425-G427 PolarHBondContact O-N 3.43Å; G427-S430 CarbonylContact O-C 3.58Å; G427-S430 PolarHBondContact O-N 3.48Å; G427-F431 WeakPolarHBondContact O-CB 3.38Å; G427-F431 PolarHBondContact O-N 2.95Å
428	A	87.2	Confident	83.8	Confident	16 Å²	16	41.9 Å²	41.9	13%	0.132	23%	0.229	C	C	.	.	H	α-helix	trans	-63.2	-48.6	177.3	0	0	0	0	0	111.5	F297 F424 V425 S430 F431 F432	F297-A428 HydrophobicContact CZ-CB 4.17Å; F424-A428 HydrophobicContact CZ-CB 4.45Å; F424-A428 VanDerWaalsContact O-CB 3.29Å; F424-A428 WeakPolarHBondContact O-CB 3.32Å; F424-A428 PolarHBondContact O-N 3.42Å; V425-A428 PolarHBondContact O-N 3.41Å; A428-S430 VanDerWaalsContact C-N 3.27Å; A428-S430 PolarHBondContact O-N 3.41Å; A428-F431 PolarHBondContact O-N 2.96Å; A428-F431 VanDerWaalsContact O-N 3.16Å; A428-F432 WeakPolarHBondContact O-CD2 3.24Å; A428-F432 PolarHBondContact O-N 3.3Å; A428-F432 VanDerWaalsContact O-N 3.09Å
429	M	88.6	Confident	85.1	Confident	1 Å²	1	43.4 Å²	43.4	1%	0.005	24%	0.237	C	C	.	.	H	α-helix	trans	-57.4	-42.8	175.6	-71.9	177.8	-176.8	0	0	111.8	I300 S301 Y304 T411 L414 V425 F431 D433	I300-M429 HydrophobicContact CG2-CE 4.04Å; S301-M429 WeakPolarHBondContact OG-CE 3.44Å; S301-M429 WeakPolarHBondContact OG-CG 3.45Å; Y304-M429 HydrophobicContact CD1-CB 3.89Å; Y304-M429 HydrophobicContact CD1-CG 4.48Å; Y304-M429 HydrophobicContact CE1-CB 4.03Å; Y304-M429 HydrophobicContact CG-SD 4.49Å; T411-M429 HydrophobicContact CG2-CE 3.88Å; T411-M429 HydrophobicContact CG2-SD 3.52Å; T411-M429 VanDerWaalsContact CG2-SD 3.52Å; L414-M429 HydrophobicContact CD2-CE 4.05Å; V425-M429 HydrophobicContact CG1-CE 3.44Å; V425-M429 VanDerWaalsContact CG1-CE 3.44Å; V425-M429 HydrophobicContact CG1-SD 4.02Å; V425-M429 WeakPolarHBondContact O-CB 3.35Å; V425-M429 VanDerWaalsContact O-CG 3.25Å; V425-M429 WeakPolarHBondContact O-CG 3.12Å; V425-M429 PolarHBondContact O-N 3.35Å; M429-F431 VanDerWaalsContact C-N 3.32Å; M429-F431 PolarHBondContact O-N 3.42Å; M429-D433 WeakPolarHBondContact O-CB 3.49Å; M429-D433 PolarHBondContact O-N 2.98Å
430	S	85.6	Confident	86.4	Confident	21 Å²	21	39.5 Å²	39.5	15%	0.147	22%	0.217	C	C	.	.	H	α-helix	trans	-74	-18	179.9	-63.4	0	0	0	0	114.4	F426 G427 A428 D433 K434	F426-S430 WeakPolarHBondContact O-CB 3.42Å; F426-S430 PolarHBondContact O-N 3.05Å; F426-S430 PolarHBondContact O-OG 3.42Å; G427-S430 CarbonylContact O-C 3.58Å; G427-S430 PolarHBondContact O-N 3.48Å; A428-S430 VanDerWaalsContact C-N 3.27Å; A428-S430 PolarHBondContact O-N 3.41Å; S430-D433 WeakPolarHBondContact CA-OD1 3.39Å; S430-K434 VanDerWaalsContact O-CD 3.3Å; S430-K434 WeakPolarHBondContact O-CD 3.48Å; S430-K434 VanDerWaalsContact O-CG 3.31Å; S430-K434 WeakPolarHBondContact O-CG 3.33Å; S430-K434 PolarHBondContact O-NZ 3.21Å
431	F	90.3	Very high	87.9	Confident	73 Å²	73	33.5 Å²	33.5	32%	0.32	19%	0.189	S	C	.	.	H	α-helix	trans	-80.1	-50.6	173.2	171.8	-90.6	0	0	0	109.2	A88 G427 A428 M429 M435	A88-F431 HydrophobicContact CB-CD2 3.77Å; A88-F431 HydrophobicContact CB-CE2 4.14Å; A88-F431 HydrophobicContact CB-CG 4.48Å; G427-F431 WeakPolarHBondContact O-CB 3.38Å; G427-F431 PolarHBondContact O-N 2.95Å; A428-F431 PolarHBondContact O-N 2.96Å; A428-F431 VanDerWaalsContact O-N 3.16Å; M429-F431 VanDerWaalsContact C-N 3.32Å; M429-F431 PolarHBondContact O-N 3.42Å; F431-M435 HydrophobicContact CD1-CG 4.38Å; F431-M435 HydrophobicContact CE1-CG 3.99Å; F431-M435 HydrophobicContact CE2-CG 4.33Å; F431-M435 HydrophobicContact CZ-CG 3.96Å; F431-M435 WeakPolarHBondContact O-CB 3.37Å; F431-M435 WeakPolarHBondContact O-CG 2.94Å; F431-M435 PolarHBondContact O-N 3.1Å
432	F	91.6	Very high	89.2	Confident	111 Å²	111	33.8 Å²	33.8	49%	0.487	19%	0.189	S	C	.	.	H	α-helix	trans	-71.4	-33.9	-176.5	-73.3	-69.6	0	0	0	113	M305 A428 L436	M305-F432 HydrophobicContact CE-CB 3.54Å; M305-F432 HydrophobicContact CG-CB 4.36Å; M305-F432 HydrophobicContact SD-CB 3.45Å; M305-F432 WeakPolarHBondContact SD-CB 3.35Å; M305-F432 HydrophobicContact SD-CG 4.41Å; A428-F432 WeakPolarHBondContact O-CD2 3.24Å; A428-F432 PolarHBondContact O-N 3.3Å; A428-F432 VanDerWaalsContact O-N 3.09Å; F432-L436 VanDerWaalsContact O-CB 3.22Å; F432-L436 WeakPolarHBondContact O-CB 3.24Å; F432-L436 PolarHBondContact O-N 3.26Å
433	D	92.7	Very high	90.4	Very high	6 Å²	6	38.4 Å²	38.4	3%	0.032	21%	0.212	C	C	.	.	H	α-helix	trans	-64.2	-43	176.1	73.4	-16.6	0	0	0	112.3	Y304 M305 R308 M429 S430 T437	Y304-D433 HydrophobicContact CE1-CB 4.14Å; Y304-D433 VanDerWaalsContact CE1-OD2 3.27Å; Y304-D433 WeakPolarHBondContact CE1-OD2 3.34Å; Y304-D433 PolarHBondContact OH-OD2 3.23Å; M305-D433 HydrophobicContact CB-CB 4.42Å; M305-D433 HydrophobicContact CG-CB 4.01Å; R308-D433 HydrophobicContact CB-CB 4.07Å; R308-D433 HydrophobicContact CG-CB 4.34Å; R308-D433 IonicContact NE-OD2 3.49Å; M429-D433 WeakPolarHBondContact O-CB 3.49Å; M429-D433 PolarHBondContact O-N 2.98Å; S430-D433 WeakPolarHBondContact CA-OD1 3.39Å; D433-T437 WeakPolarHBondContact O-CB 3.24Å; D433-T437 PolarHBondContact O-N 2.89Å; D433-T437 PolarHBondContact O-OG1 2.75Å
434	K	93.4	Very high	91.5	Very high	21 Å²	21	35.2 Å²	35.2	9%	0.091	18%	0.184	C	C	.	.	H	α-helix	trans	-66.7	-46.5	176.4	-71.7	179.4	-173	68.7	0	111.3	Q84 D87 A88 S430 L436 T437 G438	Q84-K434 PolarHBondContact OE1-O 3.44Å; D87-K434 HydrophobicContact CB-CD 3.8Å; D87-K434 VanDerWaalsContact OD2-CD 3.3Å; D87-K434 WeakPolarHBondContact OD2-CD 3.37Å; D87-K434 WeakPolarHBondContact OD2-CE 3.13Å; A88-K434 HydrophobicContact CB-CB 4.02Å; A88-K434 HydrophobicContact CB-CD 4.24Å; S430-K434 VanDerWaalsContact O-CD 3.3Å; S430-K434 WeakPolarHBondContact O-CD 3.48Å; S430-K434 VanDerWaalsContact O-CG 3.31Å; S430-K434 WeakPolarHBondContact O-CG 3.33Å; S430-K434 PolarHBondContact O-NZ 3.21Å; K434-L436 VanDerWaalsContact C-N 3.35Å; K434-L436 PolarHBondContact O-N 2.9Å; K434-T437 PolarHBondContact O-N 3.49Å; K434-G438 PolarHBondContact O-N 2.93Å
435	M	93.4	Very high	92.1	Very high	54 Å²	54	32 Å²	32	27%	0.266	17%	0.169	S	C	.	.	H	α-helix	trans	-58.5	-47.1	175.6	-78.4	-58.4	-54.8	0	0	111.7	I85 A88 F431 T437 G438 V439	I85-M435 HydrophobicContact CG1-CE 4.39Å; I85-M435 HydrophobicContact CG1-SD 3.87Å; A88-M435 HydrophobicContact CB-CG 4.31Å; F431-M435 HydrophobicContact CD1-CG 4.38Å; F431-M435 HydrophobicContact CE1-CG 3.99Å; F431-M435 HydrophobicContact CE2-CG 4.33Å; F431-M435 HydrophobicContact CZ-CG 3.96Å; F431-M435 WeakPolarHBondContact O-CB 3.37Å; F431-M435 WeakPolarHBondContact O-CG 2.94Å; F431-M435 PolarHBondContact O-N 3.1Å; M435-T437 PolarHBondContact O-N 2.9Å; M435-G438 PolarHBondContact O-N 2.87Å; M435-V439 HydrophobicContact CE-CG2 4.14Å; M435-V439 WeakPolarHBondContact O-CB 3.47Å; M435-V439 VanDerWaalsContact O-CG2 3.31Å; M435-V439 WeakPolarHBondContact O-CG2 3.4Å; M435-V439 PolarHBondContact O-N 3.49Å
436	L	94.4	Very high	92.7	Very high	62 Å²	62	34.7 Å²	34.7	33%	0.325	19%	0.189	S	C	.	.	H	α-helix	trans	-62.7	-42.8	177.8	-178.4	61.4	0	0	0	111.6	M305 L309 F432 K434 G440	M305-L436 HydrophobicContact CE-CB 4.33Å; M305-L436 HydrophobicContact CE-CD2 3.94Å; L309-L436 HydrophobicContact CB-CD2 4.41Å; L309-L436 HydrophobicContact CD1-CG 4.35Å; L309-L436 HydrophobicContact CD2-CD2 3.94Å; L309-L436 HydrophobicContact CD2-CG 4.08Å; F432-L436 VanDerWaalsContact O-CB 3.22Å; F432-L436 WeakPolarHBondContact O-CB 3.24Å; F432-L436 PolarHBondContact O-N 3.26Å; K434-L436 VanDerWaalsContact C-N 3.35Å; K434-L436 PolarHBondContact O-N 2.9Å; L436-G440 WeakPolarHBondContact O-CA 3.33Å; L436-G440 PolarHBondContact O-N 3.35Å
437	T	95.1	Very high	93.2	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-62.7	-49.4	177	-58.5	0	0	0	0	111.1	F80 N312 D433 K434 M435 G440 V441	F80-T437 HydrophobicContact CE1-CG2 4.1Å; F80-T437 HydrophobicContact CZ-CG2 4.45Å; N312-T437 HydrophobicContact CB-CG2 3.52Å; N312-T437 PolarHBondContact ND2-OG1 2.92Å; D433-T437 WeakPolarHBondContact O-CB 3.24Å; D433-T437 PolarHBondContact O-N 2.89Å; D433-T437 PolarHBondContact O-OG1 2.75Å; K434-T437 PolarHBondContact O-N 3.49Å; M435-T437 PolarHBondContact O-N 2.9Å; T437-G440 PolarHBondContact O-N 2.97Å; T437-V441 WeakPolarHBondContact O-CB 3.46Å; T437-V441 VanDerWaalsContact O-CG2 3.29Å; T437-V441 WeakPolarHBondContact O-CG2 2.99Å; T437-V441 PolarHBondContact O-N 3.49Å
438	G	96.7	Very high	93.5	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-64.1	-48.4	-178.3	0	0	0	0	0	112.9	K434 M435 G440 V441 Q442	K434-G438 PolarHBondContact O-N 2.93Å; M435-G438 PolarHBondContact O-N 2.87Å; G438-G440 VanDerWaalsContact C-N 3.35Å; G438-V441 PolarHBondContact O-N 2.9Å; G438-Q442 WeakPolarHBondContact O-CB 3.38Å; G438-Q442 PolarHBondContact O-N 2.72Å
439	V	96.3	Very high	93.5	Very high	62 Å²	62	37.1 Å²	37.1	38%	0.376	20%	0.203	S	C	.	.	H	α-helix	trans	-64.6	-41.6	176.8	173.2	0	0	0	0	110.6	L81 M435 Q442 I443	L81-V439 HydrophobicContact CD1-CG2 4.13Å; M435-V439 HydrophobicContact CE-CG2 4.14Å; M435-V439 WeakPolarHBondContact O-CB 3.47Å; M435-V439 VanDerWaalsContact O-CG2 3.31Å; M435-V439 WeakPolarHBondContact O-CG2 3.4Å; M435-V439 PolarHBondContact O-N 3.49Å; V439-Q442 WeakPolarHBondContact O-CB 3.43Å; V439-Q442 PolarHBondContact O-N 2.99Å; V439-I443 HydrophobicContact CG1-CD1 3.8Å; V439-I443 HydrophobicContact CG1-CG1 4.37Å; V439-I443 WeakPolarHBondContact O-CG1 3.28Å; V439-I443 PolarHBondContact O-N 2.97Å
440	G	96	Very high	93	Very high	19 Å²	19	45 Å²	45	20%	0.196	24%	0.241	C	C	.	.	H	α-helix	trans	-59	-49.1	175.8	0	0	0	0	0	112.1	L436 T437 G438 Q442 I443 I444	L436-G440 WeakPolarHBondContact O-CA 3.33Å; L436-G440 PolarHBondContact O-N 3.35Å; T437-G440 PolarHBondContact O-N 2.97Å; G438-G440 VanDerWaalsContact C-N 3.35Å; G440-Q442 VanDerWaalsContact C-N 3.34Å; G440-Q442 PolarHBondContact O-N 3.41Å; G440-I443 PolarHBondContact O-N 2.97Å; G440-I444 WeakPolarHBondContact O-CD1 3.3Å; G440-I444 WeakPolarHBondContact O-CG1 3.41Å; G440-I444 PolarHBondContact O-N 3.13Å
441	V	97	Very high	92.3	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-60.4	-43.4	175.4	168.8	0	0	0	0	111	L62 F80 T316 Y317 T437 G438 I443 I444 Q445	L62-V441 HydrophobicContact CD1-CG1 4.32Å; F80-V441 HydrophobicContact CB-CG1 3.98Å; F80-V441 HydrophobicContact CD1-CB 3.85Å; F80-V441 HydrophobicContact CD1-CG1 3.68Å; F80-V441 HydrophobicContact CD1-CG2 4.05Å; F80-V441 HydrophobicContact CD2-CG1 4.36Å; F80-V441 HydrophobicContact CE1-CB 4.12Å; F80-V441 HydrophobicContact CE1-CG1 4.26Å; F80-V441 HydrophobicContact CE1-CG2 3.79Å; F80-V441 HydrophobicContact CG-CB 4.43Å; F80-V441 HydrophobicContact CG-CG1 3.75Å; F80-V441 HydrophobicContact CZ-CG2 4.24Å; T316-V441 HydrophobicContact CG2-CG2 4.41Å; Y317-V441 HydrophobicContact CE2-CG2 4.06Å; Y317-V441 PolarHBondContact OH-O 3.3Å; T437-V441 WeakPolarHBondContact O-CB 3.46Å; T437-V441 VanDerWaalsContact O-CG2 3.29Å; T437-V441 WeakPolarHBondContact O-CG2 2.99Å; T437-V441 PolarHBondContact O-N 3.49Å; G438-V441 PolarHBondContact O-N 2.9Å; V441-I443 PolarHBondContact O-N 3.29Å; V441-I444 PolarHBondContact O-N 2.56Å; V441-Q445 HydrophobicContact CG1-CG 4.31Å; V441-Q445 WeakPolarHBondContact O-CB 3.42Å; V441-Q445 VanDerWaalsContact O-CG 3.29Å; V441-Q445 WeakPolarHBondContact O-CG 3.41Å; V441-Q445 PolarHBondContact O-N 3.23Å
442	Q	97.7	Very high	90.8	Very high	18 Å²	18	46.7 Å²	46.7	8%	0.084	27%	0.267	C	S	.	.	H	α-helix	trans	-59.1	-47.3	176.4	179.6	62.5	48.9	0	0	112.2	P74 G77 H78 L81 G438 V439 G440 Q445 S446	P74-Q442 PolarHBondContact O-NE2 2.9Å; G77-Q442 PolarHBondContact O-OE1 3.46Å; G77-Q442 VanDerWaalsContact O-OE1 3.14Å; H78-Q442 VanDerWaalsContact CA-OE1 3.3Å; H78-Q442 PolarHBondContact CE1-NE2 3.16Å; H78-Q442 PolarHBondContact ND1-NE2 3.38Å; H78-Q442 VanDerWaalsContact ND1-NE2 3.14Å; H78-Q442 PolarHBondContact ND1-OE1 3.38Å; L81-Q442 HydrophobicContact CB-CB 4.44Å; L81-Q442 HydrophobicContact CD2-CB 4.15Å; L81-Q442 HydrophobicContact CD2-CG 4.09Å; G438-Q442 WeakPolarHBondContact O-CB 3.38Å; G438-Q442 PolarHBondContact O-N 2.72Å; V439-Q442 WeakPolarHBondContact O-CB 3.43Å; V439-Q442 PolarHBondContact O-N 2.99Å; G440-Q442 VanDerWaalsContact C-N 3.34Å; G440-Q442 PolarHBondContact O-N 3.41Å; Q442-Q445 PolarHBondContact O-N 2.71Å; Q442-S446 PolarHBondContact NE2-OG 2.72Å; Q442-S446 VanDerWaalsContact O-CB 3.28Å; Q442-S446 WeakPolarHBondContact O-CB 3.36Å; Q442-S446 PolarHBondContact O-N 3.36Å; Q442-S446 PolarHBondContact O-OG 3.43Å
443	I	96.9	Very high	89.3	Confident	102 Å²	102	44.7 Å²	44.7	52%	0.523	28%	0.277	S	S	.	.	H	α-helix	trans	-61.5	-47.8	180	-69.7	167.5	0	0	0	109.9	V439 G440 V441 Q445 S446 V447	V439-I443 HydrophobicContact CG1-CD1 3.8Å; V439-I443 HydrophobicContact CG1-CG1 4.37Å; V439-I443 WeakPolarHBondContact O-CG1 3.28Å; V439-I443 PolarHBondContact O-N 2.97Å; G440-I443 PolarHBondContact O-N 2.97Å; V441-I443 PolarHBondContact O-N 3.29Å; I443-Q445 VanDerWaalsContact C-N 3.28Å; I443-Q445 PolarHBondContact O-N 2.89Å; I443-S446 PolarHBondContact O-N 3.34Å; I443-V447 WeakPolarHBondContact O-CG2 3.28Å; I443-V447 PolarHBondContact O-N 3.48Å; I443-V447 VanDerWaalsContact O-N 3.14Å
444	I	96.4	Very high	87.5	Confident	9 Å²	9	51.9 Å²	51.9	5%	0.046	31%	0.314	C	S	.	.	H	α-helix	trans	-57	-44	176.5	-65.3	160.9	0	0	0	110.3	Y317 G440 V441 E448 Y462 V466 I470	Y317-I444 HydrophobicContact CD2-CD1 4.48Å; Y317-I444 HydrophobicContact CE1-CG2 3.76Å; Y317-I444 HydrophobicContact CE2-CB 4.44Å; Y317-I444 HydrophobicContact CE2-CD1 3.68Å; Y317-I444 HydrophobicContact CE2-CG2 4.06Å; Y317-I444 VanDerWaalsContact CZ-CG2 3.44Å; Y317-I444 WeakPolarHBondContact OH-CB 2.98Å; Y317-I444 VanDerWaalsContact OH-CG2 3.25Å; Y317-I444 WeakPolarHBondContact OH-CG2 3.21Å; G440-I444 WeakPolarHBondContact O-CD1 3.3Å; G440-I444 WeakPolarHBondContact O-CG1 3.41Å; G440-I444 PolarHBondContact O-N 3.13Å; V441-I444 PolarHBondContact O-N 2.56Å; I444-E448 PolarHBondContact O-N 2.79Å; I444-Y462 VanDerWaalsContact C-OH 3.3Å; I444-Y462 WeakPolarHBondContact CA-OH 3.37Å; I444-Y462 HydrophobicContact CG2-CE1 4.17Å; I444-Y462 WeakPolarHBondContact CG2-OH 3.39Å; I444-Y462 PolarHBondContact O-OH 3.38Å; I444-V466 HydrophobicContact CD1-CG1 4.21Å; I444-V466 HydrophobicContact CG2-CB 4.49Å; I444-V466 HydrophobicContact CG2-CG1 4Å; I444-V466 HydrophobicContact CG2-CG2 3.61Å; I444-I470 HydrophobicContact CD1-CD1 3.39Å; I444-I470 HydrophobicContact CG1-CD1 3.48Å; I444-I470 VanDerWaalsContact CG1-CD1 3.48Å
445	Q	95.5	Very high	85.9	Confident	0 Å²	0	53 Å²	53	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-73.2	-31	179.7	-69.8	-60.5	-5.2	0	0	113.4	L62 G73 P74 Y317 V441 Q442 I443 E448	L62-Q445 VanDerWaalsContact CD1-NE2 3.31Å; L62-Q445 HydrophobicContact CD2-CG 4.43Å; G73-Q445 CarbonylContact C-O 3.54Å; G73-Q445 WeakPolarHBondContact CA-O 3.21Å; G73-Q445 VanDerWaalsContact O-CB 3.29Å; G73-Q445 WeakPolarHBondContact O-CB 3.29Å; P74-Q445 WeakPolarHBondContact CD-O 3.43Å; Y317-Q445 VanDerWaalsContact CE1-NE2 3.3Å; Y317-Q445 WeakPolarHBondContact OH-CG 3.36Å; Y317-Q445 PolarHBondContact OH-NE2 2.96Å; V441-Q445 HydrophobicContact CG1-CG 4.31Å; V441-Q445 WeakPolarHBondContact O-CB 3.42Å; V441-Q445 VanDerWaalsContact O-CG 3.29Å; V441-Q445 WeakPolarHBondContact O-CG 3.41Å; V441-Q445 PolarHBondContact O-N 3.23Å; Q442-Q445 PolarHBondContact O-N 2.71Å; I443-Q445 VanDerWaalsContact C-N 3.28Å; I443-Q445 PolarHBondContact O-N 2.89Å; Q445-E448 PolarHBondContact OE1-OE2 2.78Å; Q445-E448 VanDerWaalsContact OE1-OE2 3.12Å
446	S	94.6	Very high	84.7	Confident	58 Å²	58	52 Å²	52	41%	0.406	32%	0.321	S	S	.	.	H	α-helix	trans	-71.8	-28.9	-179.4	-78.7	0	0	0	0	113.9	Q442 I443	Q442-S446 PolarHBondContact NE2-OG 2.72Å; Q442-S446 VanDerWaalsContact O-CB 3.28Å; Q442-S446 WeakPolarHBondContact O-CB 3.36Å; Q442-S446 PolarHBondContact O-N 3.36Å; Q442-S446 PolarHBondContact O-OG 3.43Å; I443-S446 PolarHBondContact O-N 3.34Å
447	V	93.4	Very high	83.6	Confident	93 Å²	93	55.9 Å²	55.9	56%	0.564	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.6	7	179.8	-53.3	0	0	0	0	113.2	I443 Y462	I443-V447 WeakPolarHBondContact O-CG2 3.28Å; I443-V447 PolarHBondContact O-N 3.48Å; I443-V447 VanDerWaalsContact O-N 3.14Å; V447-Y462 HydrophobicContact CG2-CE2 4.13Å; V447-Y462 WeakPolarHBondContact CG2-OH 3.4Å
448	E	90.6	Very high	82.7	Confident	33 Å²	33	62.5 Å²	62.5	15%	0.154	37%	0.366	C	S	.	.	P	Polyproline II helix	trans	-61.7	128.7	177.4	-176.4	-177.9	-173.9	0	0	111	K66 I444 Q445 M450 Y462 F463	K66-E448 WeakPolarHBondContact CE-OE2 3.41Å; K66-E448 IonicContact NZ-OE1 2.62Å; K66-E448 PolarHBondContact NZ-OE1 3.24Å; K66-E448 IonicContact NZ-OE2 3.07Å; K66-E448 PolarHBondContact NZ-OE2 2.94Å; I444-E448 PolarHBondContact O-N 2.79Å; Q445-E448 PolarHBondContact OE1-OE2 2.78Å; Q445-E448 VanDerWaalsContact OE1-OE2 3.12Å; E448-M450 PolarHBondContact O-N 3.14Å; E448-Y462 HydrophobicContact CB-CD1 4.4Å; E448-Y462 HydrophobicContact CB-CE1 3.93Å; E448-Y462 HydrophobicContact CG-CD1 4.02Å; E448-Y462 HydrophobicContact CG-CE1 4.01Å; E448-F463 WeakPolarHBondContact OE1-CZ 3.27Å
449	P	87.1	Confident	81.8	Confident	36 Å²	36	65 Å²	65	23%	0.234	38%	0.376	C	S	.	.	P	Polyproline II helix	trans	-68.9	133.9	177.8	28.2	-33.8	0	0	0	111.3	K458 R459 Y462	P449-K458 HydrophobicContact CG-CB 4.44Å; P449-R459 HydrophobicContact CG-CB 4.38Å; P449-Y462 HydrophobicContact CG-CD2 4.5Å; P449-Y462 HydrophobicContact CG-CG 4.22Å
450	M	78.5	Confident	81	Confident	166 Å²	166	64.1 Å²	64.1	82%	0.818	37%	0.369	S	S	*	.	P	Polyproline II helix	trans	-61.6	136.7	169.4	-68.7	-172.8	157.2	0	0	110.3	E448 T455	E448-M450 PolarHBondContact O-N 3.14Å; M450-T455 WeakPolarHBondContact O-CB 3.5Å; M450-T455 PolarHBondContact O-OG1 2.88Å
451	C	70.8	Confident	80.6	Confident	57 Å²	57	66.5 Å²	66.5	39%	0.385	38%	0.377	S	S	.	.			trans	-93.2	104.8	172	168.2	0	0	0	0	110.1	C456	C451-C456 HydrophobicContact CB-CB 4.09Å; C451-C456 WeakPolarHBondContact CB-SG 3.49Å; C451-C456 WeakPolarHBondContact SG-CB 3.45Å; C451-C456 CovalentContact SG-SG 2.06Å; C451-C456 PolarHBondContact SG-SG 3.4Å
452	A	58.2	Low	80.4	Confident	74 Å²	74	68.2 Å²	68.2	61%	0.612	38%	0.383	S	S	*	.	S	Bend	trans	-137.4	108.1	166.5	0	0	0	0	0	109.2	L454 T455	A452-L454 PolarHBondContact O-N 3.25Å; A452-T455 WeakPolarHBondContact CA-OG1 3.43Å; A452-T455 PolarHBondContact N-OG1 3.1Å; A452-T455 PolarHBondContact O-N 3.06Å; A452-T455 PolarHBondContact O-OG1 3.32Å
453	G	60.6	Low	80.2	Confident	68 Å²	68	67.3 Å²	67.3	70%	0.701	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	61.7	-127	-179.9	0	0	0	0	0	113.6	T455 C456	G453-T455 PolarHBondContact O-N 2.77Å; G453-C456 PolarHBondContact O-N 2.88Å
454	L	55	Low	80.1	Confident	157 Å²	157	63.7 Å²	63.7	82%	0.822	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.2	-21.2	178.9	-84.1	124.1	0	0	0	114.7	A452 C456	A452-L454 PolarHBondContact O-N 3.25Å; L454-C456 PolarHBondContact O-N 3.22Å
455	T	59.5	Low	80	Confident	45 Å²	45	68.3 Å²	68.3	28%	0.276	38%	0.377	S	S	.	.	H	α-helix	trans	-72.4	-12.6	178	54.8	0	0	0	0	113.2	M450 A452 G453 K458 R459	M450-T455 WeakPolarHBondContact O-CB 3.5Å; M450-T455 PolarHBondContact O-OG1 2.88Å; A452-T455 WeakPolarHBondContact CA-OG1 3.43Å; A452-T455 PolarHBondContact N-OG1 3.1Å; A452-T455 PolarHBondContact O-N 3.06Å; A452-T455 PolarHBondContact O-OG1 3.32Å; G453-T455 PolarHBondContact O-N 2.77Å; T455-K458 WeakPolarHBondContact O-CB 3.35Å; T455-K458 PolarHBondContact O-N 3.2Å; T455-R459 PolarHBondContact O-N 3.44Å
456	C	68.6	Low	80	Confident	33 Å²	33	68.5 Å²	68.5	22%	0.223	38%	0.379	C	S	.	.	H	α-helix	trans	-68.5	-34.1	176	-129.9	0	0	0	0	112.9	C451 G453 L454 K458 R459 N460	C451-C456 HydrophobicContact CB-CB 4.09Å; C451-C456 WeakPolarHBondContact CB-SG 3.49Å; C451-C456 WeakPolarHBondContact SG-CB 3.45Å; C451-C456 CovalentContact SG-SG 2.06Å; C451-C456 PolarHBondContact SG-SG 3.4Å; G453-C456 PolarHBondContact O-N 2.88Å; L454-C456 PolarHBondContact O-N 3.22Å; C456-K458 PolarHBondContact O-N 3.23Å; C456-R459 WeakPolarHBondContact O-CA 3.44Å; C456-R459 WeakPolarHBondContact O-CB 3.37Å; C456-R459 PolarHBondContact O-N 3.44Å; C456-N460 PolarHBondContact O-N 2.82Å; C456-N460 PolarHBondContact O-OD1 3.26Å
457	E	71.7	Confident	80.1	Confident	143 Å²	143	65.8 Å²	65.8	67%	0.668	36%	0.359	S	S	*	.	H	α-helix	trans	-59.7	-37.4	171.9	-70.8	-174.2	173.6	0	0	111.6	R459 N460 L461	E457-R459 VanDerWaalsContact C-N 3.29Å; E457-R459 PolarHBondContact O-N 2.68Å; E457-N460 PolarHBondContact O-N 3.2Å; E457-L461 PolarHBondContact O-N 3.09Å; E457-L461 VanDerWaalsContact O-N 3.13Å
458	K	75.8	Confident	80.3	Confident	140 Å²	140	62.1 Å²	62.1	61%	0.609	34%	0.337	S	S	*	.	H	α-helix	trans	-63.8	-35.3	174.3	-63.9	-177.9	173.9	179.3	0	111.7	P449 T455 C456 L461 Y462	P449-K458 HydrophobicContact CG-CB 4.44Å; T455-K458 WeakPolarHBondContact O-CB 3.35Å; T455-K458 PolarHBondContact O-N 3.2Å; C456-K458 PolarHBondContact O-N 3.23Å; K458-L461 PolarHBondContact O-N 2.75Å; K458-Y462 WeakPolarHBondContact O-CB 3.5Å; K458-Y462 PolarHBondContact O-N 3.34Å
459	R	77.8	Confident	80.5	Confident	53 Å²	53	63.5 Å²	63.5	20%	0.2	35%	0.35	C	S	.	.	H	α-helix	trans	-67.9	-41.9	175.5	-168.7	179.3	76.7	-164.4	-0.4	111.9	E324 P449 T455 C456 E457 L461 Y462 F463	E324-R459 VanDerWaalsContact CD-NE 3.33Å; E324-R459 IonicContact OE1-CZ 3.73Å; E324-R459 IonicContact OE1-NE 2.73Å; E324-R459 PolarHBondContact OE1-NE 2.89Å; E324-R459 IonicContact OE1-NH1 2.86Å; E324-R459 IonicContact OE1-NH2 3.69Å; E324-R459 PolarHBondContact OE1-NH2 2.94Å; E324-R459 IonicContact OE2-CZ 3.33Å; E324-R459 IonicContact OE2-NE 2.69Å; E324-R459 PolarHBondContact OE2-NE 3.02Å; E324-R459 IonicContact OE2-NH2 3.86Å; E324-R459 PolarHBondContact OE2-NH2 3.09Å; P449-R459 HydrophobicContact CG-CB 4.38Å; T455-R459 PolarHBondContact O-N 3.44Å; C456-R459 WeakPolarHBondContact O-CA 3.44Å; C456-R459 WeakPolarHBondContact O-CB 3.37Å; C456-R459 PolarHBondContact O-N 3.44Å; E457-R459 VanDerWaalsContact C-N 3.29Å; E457-R459 PolarHBondContact O-N 2.68Å; R459-L461 PolarHBondContact O-N 3.28Å; R459-Y462 VanDerWaalsContact O-CB 3.28Å; R459-Y462 WeakPolarHBondContact O-CB 3.48Å; R459-Y462 PolarHBondContact O-N 3.06Å; R459-F463 HydrophobicContact CG-CE2 4.21Å; R459-F463 PolarHBondContact O-N 2.8Å
460	N	80.1	Confident	81	Confident	42 Å²	42	64.2 Å²	64.2	23%	0.225	35%	0.351	C	S	.	.	H	α-helix	trans	-59.4	-41.7	176.8	-64	6.2	0	0	0	110.5	E324 T325 C456 E457	E324-N460 PolarHBondContact O-OD1 3.35Å; T325-N460 WeakPolarHBondContact CB-O 3.36Å; T325-N460 WeakPolarHBondContact CG2-O 3.5Å; T325-N460 PolarHBondContact OG1-O 3.04Å; C456-N460 PolarHBondContact O-N 2.82Å; C456-N460 PolarHBondContact O-OD1 3.26Å; E457-N460 PolarHBondContact O-N 3.2Å
461	L	87.8	Confident	81.9	Confident	70 Å²	70	56.3 Å²	56.3	37%	0.366	31%	0.312	S	S	.	.	H	α-helix	trans	-72.5	-26.7	175.7	-170.4	62.7	0	0	0	113.1	E457 K458 R459 K464 Y465	E457-L461 PolarHBondContact O-N 3.09Å; E457-L461 VanDerWaalsContact O-N 3.13Å; K458-L461 PolarHBondContact O-N 2.75Å; R459-L461 PolarHBondContact O-N 3.28Å; L461-K464 HydrophobicContact CD1-CD 3.98Å; L461-K464 VanDerWaalsContact O-CB 3.28Å; L461-K464 WeakPolarHBondContact O-CB 3.48Å; L461-K464 PolarHBondContact O-N 3.46Å; L461-Y465 HydrophobicContact CD1-CD2 4.42Å; L461-Y465 HydrophobicContact CD1-CE2 3.94Å; L461-Y465 HydrophobicContact CD2-CD2 4.48Å; L461-Y465 HydrophobicContact CD2-CE2 3.6Å; L461-Y465 HydrophobicContact CG-CD2 3.86Å; L461-Y465 HydrophobicContact CG-CE2 3.4Å; L461-Y465 VanDerWaalsContact CG-CE2 3.4Å; L461-Y465 WeakPolarHBondContact O-CD2 3.16Å; L461-Y465 PolarHBondContact O-N 2.81Å; L461-Y465 VanDerWaalsContact O-N 3.11Å
462	Y	92.5	Very high	83.1	Confident	35 Å²	35	54.5 Å²	54.5	14%	0.137	30%	0.3	C	S	.	.	H	α-helix	trans	-62.9	-55.3	-177.3	-178.2	-108.5	0	0	0	112.9	I444 V447 E448 P449 K458 R459 K464 Y465 V466	I444-Y462 VanDerWaalsContact C-OH 3.3Å; I444-Y462 WeakPolarHBondContact CA-OH 3.37Å; I444-Y462 HydrophobicContact CG2-CE1 4.17Å; I444-Y462 WeakPolarHBondContact CG2-OH 3.39Å; I444-Y462 PolarHBondContact O-OH 3.38Å; V447-Y462 HydrophobicContact CG2-CE2 4.13Å; V447-Y462 WeakPolarHBondContact CG2-OH 3.4Å; E448-Y462 HydrophobicContact CB-CD1 4.4Å; E448-Y462 HydrophobicContact CB-CE1 3.93Å; E448-Y462 HydrophobicContact CG-CD1 4.02Å; E448-Y462 HydrophobicContact CG-CE1 4.01Å; P449-Y462 HydrophobicContact CG-CD2 4.5Å; P449-Y462 HydrophobicContact CG-CG 4.22Å; K458-Y462 WeakPolarHBondContact O-CB 3.5Å; K458-Y462 PolarHBondContact O-N 3.34Å; R459-Y462 VanDerWaalsContact O-CB 3.28Å; R459-Y462 WeakPolarHBondContact O-CB 3.48Å; R459-Y462 PolarHBondContact O-N 3.06Å; Y462-K464 PolarHBondContact O-N 3.18Å; Y462-Y465 WeakPolarHBondContact O-CB 3.32Å; Y462-Y465 PolarHBondContact O-N 3.38Å; Y462-V466 HydrophobicContact CD1-CG2 4.3Å; Y462-V466 HydrophobicContact CE1-CG2 3.85Å; Y462-V466 HydrophobicContact CE2-CG2 4.35Å; Y462-V466 WeakPolarHBondContact O-CG2 3.47Å; Y462-V466 PolarHBondContact O-N 3.04Å
463	F	93.2	Very high	85	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-65.6	-25.9	179.4	-72.7	-66.8	0	0	0	112.7	Y317 L320 E324 T325 E448 R459 V466 M467	Y317-F463 AromaticContact CD1-CD1 3.88Å; Y317-F463 HydrophobicContact CD1-CD1 3.88Å; Y317-F463 AromaticContact CD1-CE1 3.67Å; Y317-F463 HydrophobicContact CD1-CE1 3.67Å; Y317-F463 HydrophobicContact CE1-CD1 4.47Å; Y317-F463 AromaticContact CE1-CE1 3.88Å; Y317-F463 HydrophobicContact CE1-CE1 3.88Å; L320-F463 HydrophobicContact CB-CD1 4.14Å; L320-F463 HydrophobicContact CB-CE1 4.09Å; L320-F463 HydrophobicContact CB-CG 4.46Å; L320-F463 HydrophobicContact CB-CZ 4.35Å; L320-F463 HydrophobicContact CD1-CE1 3.94Å; L320-F463 HydrophobicContact CD1-CZ 4.11Å; E324-F463 HydrophobicContact CB-CD2 3.71Å; E324-F463 HydrophobicContact CB-CE2 4.23Å; E324-F463 HydrophobicContact CG-CD2 3.93Å; E324-F463 HydrophobicContact CG-CE2 3.96Å; T325-F463 WeakPolarHBondContact OG1-CB 3.21Å; E448-F463 WeakPolarHBondContact OE1-CZ 3.27Å; R459-F463 HydrophobicContact CG-CE2 4.21Å; R459-F463 PolarHBondContact O-N 2.8Å; F463-V466 PolarHBondContact O-N 2.8Å; F463-M467 WeakPolarHBondContact O-CB 3.48Å; F463-M467 WeakPolarHBondContact O-CG 3.47Å; F463-M467 PolarHBondContact O-N 2.66Å
464	K	93.9	Very high	86.8	Confident	25 Å²	25	50.3 Å²	50.3	11%	0.109	26%	0.258	C	S	.	.	H	α-helix	trans	-60.2	-49.6	168.5	-168.8	177.8	171.9	-178.6	0	111.7	Y321 T325 W381 L461 Y462 V466 M467 V468	Y321-K464 HydrophobicContact CE2-CB 4.43Å; Y321-K464 HydrophobicContact CE2-CG 4.48Å; T325-K464 HydrophobicContact CG2-CB 3.82Å; T325-K464 HydrophobicContact CG2-CD 4.46Å; T325-K464 HydrophobicContact CG2-CG 4.35Å; T325-K464 PolarHBondContact OG1-N 3.5Å; W381-K464 VanDerWaalsContact CA-CE 3.45Å; W381-K464 HydrophobicContact CE3-CG 4.5Å; W381-K464 WeakPolarHBondContact O-CE 3.46Å; W381-K464 PolarHBondContact O-NZ 2.96Å; L461-K464 HydrophobicContact CD1-CD 3.98Å; L461-K464 VanDerWaalsContact O-CB 3.28Å; L461-K464 WeakPolarHBondContact O-CB 3.48Å; L461-K464 PolarHBondContact O-N 3.46Å; Y462-K464 PolarHBondContact O-N 3.18Å; K464-V466 VanDerWaalsContact C-N 3.34Å; K464-V466 PolarHBondContact O-N 3.35Å; K464-M467 PolarHBondContact O-N 2.83Å; K464-V468 HydrophobicContact CG-CG2 4.38Å; K464-V468 WeakPolarHBondContact O-CB 3.31Å; K464-V468 WeakPolarHBondContact O-CG2 3.35Å; K464-V468 PolarHBondContact O-N 2.98Å
465	Y	94.8	Very high	88.8	Confident	106 Å²	106	42.8 Å²	42.8	42%	0.416	22%	0.219	S	C	.	.	H	α-helix	trans	-62.4	-40.4	175.2	-77.6	-65.8	0	0	0	112.4	W381 L461 Y462 M467 V468 C469	W381-Y465 HydrophobicContact CH2-CD1 4.28Å; W381-Y465 AromaticContact CH2-CE1 3.52Å; W381-Y465 HydrophobicContact CH2-CE1 3.52Å; W381-Y465 AromaticContact CH2-CZ 3.92Å; W381-Y465 AromaticContact CZ3-CD1 3.87Å; W381-Y465 HydrophobicContact CZ3-CD1 3.87Å; W381-Y465 AromaticContact CZ3-CE1 3.58Å; W381-Y465 HydrophobicContact CZ3-CE1 3.58Å; L461-Y465 HydrophobicContact CD1-CD2 4.42Å; L461-Y465 HydrophobicContact CD1-CE2 3.94Å; L461-Y465 HydrophobicContact CD2-CD2 4.48Å; L461-Y465 HydrophobicContact CD2-CE2 3.6Å; L461-Y465 HydrophobicContact CG-CD2 3.86Å; L461-Y465 HydrophobicContact CG-CE2 3.4Å; L461-Y465 VanDerWaalsContact CG-CE2 3.4Å; L461-Y465 WeakPolarHBondContact O-CD2 3.16Å; L461-Y465 PolarHBondContact O-N 2.81Å; L461-Y465 VanDerWaalsContact O-N 3.11Å; Y462-Y465 WeakPolarHBondContact O-CB 3.32Å; Y462-Y465 PolarHBondContact O-N 3.38Å; Y465-M467 PolarHBondContact O-N 3.17Å; Y465-V468 PolarHBondContact O-N 3.27Å; Y465-C469 WeakPolarHBondContact O-CB 3.27Å; Y465-C469 PolarHBondContact O-N 2.88Å
466	V	96.2	Very high	90.7	Very high	5 Å²	5	45 Å²	45	3%	0.03	23%	0.229	C	C	.	.	H	α-helix	trans	-58.5	-49.9	176.4	171.9	0	0	0	0	110.8	V313 Y317 I444 Y462 F463 K464 I470 P471	V313-V466 HydrophobicContact CG1-CG1 4.42Å; Y317-V466 HydrophobicContact CD1-CG1 4.24Å; Y317-V466 HydrophobicContact CD2-CG1 3.88Å; Y317-V466 HydrophobicContact CE2-CG1 4.31Å; Y317-V466 HydrophobicContact CG-CG1 3.83Å; I444-V466 HydrophobicContact CD1-CG1 4.21Å; I444-V466 HydrophobicContact CG2-CB 4.49Å; I444-V466 HydrophobicContact CG2-CG1 4Å; I444-V466 HydrophobicContact CG2-CG2 3.61Å; Y462-V466 HydrophobicContact CD1-CG2 4.3Å; Y462-V466 HydrophobicContact CE1-CG2 3.85Å; Y462-V466 HydrophobicContact CE2-CG2 4.35Å; Y462-V466 WeakPolarHBondContact O-CG2 3.47Å; Y462-V466 PolarHBondContact O-N 3.04Å; F463-V466 PolarHBondContact O-N 2.8Å; K464-V466 VanDerWaalsContact C-N 3.34Å; K464-V466 PolarHBondContact O-N 3.35Å; V466-I470 HydrophobicContact CG1-CD1 4.3Å; V466-I470 WeakPolarHBondContact O-CB 3.21Å; V466-I470 PolarHBondContact O-N 2.98Å; V466-P471 WeakPolarHBondContact O-CD 3.43Å
467	M	96	Very high	92	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-74.9	-24.5	-176.7	-69.7	-58.6	-74	0	0	114.3	T314 Y317 L318 Y321 M380 F463 K464 Y465 P471	T314-M467 HydrophobicContact CG2-CE 3.87Å; Y317-M467 VanDerWaalsContact CB-SD 3.5Å; L318-M467 HydrophobicContact CB-CE 3.95Å; L318-M467 HydrophobicContact CD1-CE 4.27Å; Y321-M467 HydrophobicContact CD2-CB 4.04Å; Y321-M467 HydrophobicContact CD2-CG 3.82Å; Y321-M467 HydrophobicContact CE2-CB 4.43Å; Y321-M467 HydrophobicContact CG-CB 4.48Å; Y321-M467 HydrophobicContact CG-CG 3.89Å; M380-M467 HydrophobicContact CE-CB 3.73Å; M380-M467 HydrophobicContact CE-CE 3.5Å; M380-M467 VanDerWaalsContact CE-CE 3.5Å; M380-M467 HydrophobicContact CE-CG 3.92Å; M380-M467 HydrophobicContact SD-CB 4.07Å; M380-M467 HydrophobicContact SD-CE 3.88Å; F463-M467 WeakPolarHBondContact O-CB 3.48Å; F463-M467 WeakPolarHBondContact O-CG 3.47Å; F463-M467 PolarHBondContact O-N 2.66Å; K464-M467 PolarHBondContact O-N 2.83Å; Y465-M467 PolarHBondContact O-N 3.17Å; M467-P471 VanDerWaalsContact O-CG 3.26Å; M467-P471 WeakPolarHBondContact O-CG 3.43Å
468	V	96.8	Very high	93.3	Very high	16 Å²	16	41.1 Å²	41.1	10%	0.097	21%	0.21	C	C	.	.	H	α-helix	trans	-90.4	-55.7	179	178.8	0	0	0	0	110.5	S377 M380 W381 K464 Y465 S472	S377-V468 VanDerWaalsContact O-CG2 3.31Å; S377-V468 WeakPolarHBondContact O-CG2 3.18Å; M380-V468 HydrophobicContact CB-CG2 4.05Å; W381-V468 HydrophobicContact CB-CG2 4.27Å; W381-V468 HydrophobicContact CE3-CB 4.26Å; W381-V468 HydrophobicContact CE3-CG1 4.03Å; W381-V468 HydrophobicContact CE3-CG2 4.05Å; K464-V468 HydrophobicContact CG-CG2 4.38Å; K464-V468 WeakPolarHBondContact O-CB 3.31Å; K464-V468 WeakPolarHBondContact O-CG2 3.35Å; K464-V468 PolarHBondContact O-N 2.98Å; Y465-V468 PolarHBondContact O-N 3.27Å; V468-S472 WeakPolarHBondContact O-CB 3.23Å; V468-S472 PolarHBondContact O-N 3.06Å; V468-S472 PolarHBondContact O-OG 2.88Å
469	C	96.2	Very high	94.3	Very high	62 Å²	62	36.4 Å²	36.4	42%	0.419	19%	0.191	S	C	.	.	H	α-helix	trans	-76.2	-44.5	-168.9	-63.1	0	0	0	0	112.9	Y465 A473	Y465-C469 WeakPolarHBondContact O-CB 3.27Å; Y465-C469 PolarHBondContact O-N 2.88Å; C469-A473 WeakPolarHBondContact O-CB 3.35Å; C469-A473 PolarHBondContact O-N 3.4Å
470	I	96.4	Very high	95.3	Very high	52 Å²	52	38.5 Å²	38.5	27%	0.267	21%	0.205	S	C	.	.	H	α-helix	trans	-72.1	-50.7	-172.6	-59.4	178.2	0	0	0	111.2	V313 I444 V466 S472 A473 S474	V313-I470 HydrophobicContact CG1-CB 4.38Å; V313-I470 HydrophobicContact CG1-CG2 4.06Å; V313-I470 HydrophobicContact CG2-CG2 4.15Å; I444-I470 HydrophobicContact CD1-CD1 3.39Å; I444-I470 HydrophobicContact CG1-CD1 3.48Å; I444-I470 VanDerWaalsContact CG1-CD1 3.48Å; V466-I470 HydrophobicContact CG1-CD1 4.3Å; V466-I470 WeakPolarHBondContact O-CB 3.21Å; V466-I470 PolarHBondContact O-N 2.98Å; I470-S472 PolarHBondContact O-N 3Å; I470-A473 PolarHBondContact O-N 3.49Å; I470-S474 WeakPolarHBondContact O-CB 3.39Å; I470-S474 PolarHBondContact O-N 3.32Å; I470-S474 PolarHBondContact O-OG 2.99Å
471	P	97.6	Very high	96	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-51.9	-50.2	169	-36.1	43.6	0	0	0	113.4	F310 V313 S377 V466 M467 S474 L475	F310-P471 HydrophobicContact CD2-CB 3.61Å; F310-P471 HydrophobicContact CE2-CB 3.92Å; V313-P471 HydrophobicContact CG1-CG 4.14Å; S377-P471 VanDerWaalsContact OG-CB 3.22Å; S377-P471 WeakPolarHBondContact OG-CB 3.4Å; V466-P471 WeakPolarHBondContact O-CD 3.43Å; M467-P471 VanDerWaalsContact O-CG 3.26Å; M467-P471 WeakPolarHBondContact O-CG 3.43Å; P471-S474 WeakPolarHBondContact O-CB 3.08Å; P471-S474 PolarHBondContact O-N 3.46Å; P471-L475 WeakPolarHBondContact O-CG 3.46Å; P471-L475 PolarHBondContact O-N 2.78Å
472	S	97.7	Very high	96.4	Very high	18 Å²	18	33.4 Å²	33.4	13%	0.126	18%	0.179	C	C	.	.	H	α-helix	trans	-64.8	-44.3	-178.7	-57.3	0	0	0	0	112.3	S377 V468 I470 S474 L475 L476	S377-S472 WeakPolarHBondContact CB-OG 3.4Å; V468-S472 WeakPolarHBondContact O-CB 3.23Å; V468-S472 PolarHBondContact O-N 3.06Å; V468-S472 PolarHBondContact O-OG 2.88Å; I470-S472 PolarHBondContact O-N 3Å; S472-S474 VanDerWaalsContact C-N 3.32Å; S472-S474 PolarHBondContact O-N 3.5Å; S472-L475 PolarHBondContact O-N 3.32Å; S472-L476 WeakPolarHBondContact O-CB 3.33Å; S472-L476 VanDerWaalsContact O-CG 3.25Å; S472-L476 WeakPolarHBondContact O-CG 3.44Å; S472-L476 PolarHBondContact O-N 2.98Å
473	A	97.4	Very high	96.5	Very high	48 Å²	48	36.6 Å²	36.6	40%	0.397	20%	0.197	S	C	.	.	H	α-helix	trans	-61.9	-41.3	177	0	0	0	0	0	111.6	C469 I470 L475 L476 L477	C469-A473 WeakPolarHBondContact O-CB 3.35Å; C469-A473 PolarHBondContact O-N 3.4Å; I470-A473 PolarHBondContact O-N 3.49Å; A473-L475 VanDerWaalsContact C-N 3.34Å; A473-L475 PolarHBondContact O-N 3.41Å; A473-L476 PolarHBondContact O-N 3.45Å; A473-L477 WeakPolarHBondContact O-CB 3.3Å; A473-L477 VanDerWaalsContact O-CG 3.3Å; A473-L477 WeakPolarHBondContact O-CG 3.29Å; A473-L477 PolarHBondContact O-N 3.07Å
474	S	97.4	Very high	96.6	Very high	6 Å²	6	40.9 Å²	40.9	4%	0.042	22%	0.22	C	C	.	.	H	α-helix	trans	-59.5	-45.8	175.7	-54.8	0	0	0	0	111.1	L309 I470 P471 S472 A478	L309-S474 WeakPolarHBondContact CD2-OG 3.48Å; I470-S474 WeakPolarHBondContact O-CB 3.39Å; I470-S474 PolarHBondContact O-N 3.32Å; I470-S474 PolarHBondContact O-OG 2.99Å; P471-S474 WeakPolarHBondContact O-CB 3.08Å; P471-S474 PolarHBondContact O-N 3.46Å; S472-S474 VanDerWaalsContact C-N 3.32Å; S472-S474 PolarHBondContact O-N 3.5Å; S474-A478 WeakPolarHBondContact O-CB 3.41Å; S474-A478 PolarHBondContact O-N 2.88Å
475	L	98.5	Very high	96.5	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-71.3	-35.4	179.3	-68.4	-177.6	0	0	0	113.6	F310 I370 V374 L403 P471 S472 A473 A478 L479	F310-L475 HydrophobicContact CB-CD2 3.92Å; F310-L475 HydrophobicContact CB-CG 4.17Å; F310-L475 HydrophobicContact CD1-CD2 4.12Å; F310-L475 HydrophobicContact CD2-CD1 3.55Å; F310-L475 HydrophobicContact CD2-CD2 4.06Å; F310-L475 HydrophobicContact CD2-CG 3.67Å; F310-L475 HydrophobicContact CE2-CD1 3.63Å; F310-L475 HydrophobicContact CE2-CG 4.28Å; F310-L475 HydrophobicContact CG-CD1 4.09Å; F310-L475 HydrophobicContact CG-CD2 3.75Å; F310-L475 HydrophobicContact CG-CG 3.89Å; F310-L475 HydrophobicContact CZ-CD1 4.2Å; I370-L475 HydrophobicContact CG1-CD2 4.42Å; I370-L475 HydrophobicContact CG2-CB 4.32Å; V374-L475 HydrophobicContact CG2-CB 3.78Å; V374-L475 HydrophobicContact CG2-CD1 3.99Å; L403-L475 HydrophobicContact CD1-CD2 3.54Å; P471-L475 WeakPolarHBondContact O-CG 3.46Å; P471-L475 PolarHBondContact O-N 2.78Å; S472-L475 PolarHBondContact O-N 3.32Å; A473-L475 VanDerWaalsContact C-N 3.34Å; A473-L475 PolarHBondContact O-N 3.41Å; L475-A478 CarbonylContact O-C 3.55Å; L475-A478 WeakPolarHBondContact O-CB 3.39Å; L475-A478 PolarHBondContact O-N 2.94Å; L475-L479 WeakPolarHBondContact O-CB 3.48Å; L475-L479 PolarHBondContact O-N 3.35Å
476	L	97.9	Very high	96.3	Very high	91 Å²	91	40.4 Å²	40.4	48%	0.476	22%	0.217	S	C	.	.	H	α-helix	trans	-68.7	-38.5	175.2	-70.9	173	0	0	0	111.7	S472 A473 A478 L479 I480	S472-L476 WeakPolarHBondContact O-CB 3.33Å; S472-L476 VanDerWaalsContact O-CG 3.25Å; S472-L476 WeakPolarHBondContact O-CG 3.44Å; S472-L476 PolarHBondContact O-N 2.98Å; A473-L476 PolarHBondContact O-N 3.45Å; L476-A478 VanDerWaalsContact C-N 3.33Å; L476-L479 WeakPolarHBondContact O-CB 3.24Å; L476-L479 PolarHBondContact O-N 2.93Å; L476-I480 WeakPolarHBondContact O-CG1 3.38Å; L476-I480 PolarHBondContact O-N 3.36Å; L476-I480 VanDerWaalsContact O-N 3.12Å
477	L	97.5	Very high	96	Very high	94 Å²	94	45.4 Å²	45.4	49%	0.492	25%	0.249	S	C	.	.	H	α-helix	trans	-65.4	-38.5	170.7	-69.5	174.2	0	0	0	111.1	L306 A473 L479 I480 T481	L306-L477 HydrophobicContact CD1-CB 3.63Å; L306-L477 HydrophobicContact CD2-CB 4.08Å; L306-L477 HydrophobicContact CD2-CD1 4.2Å; A473-L477 WeakPolarHBondContact O-CB 3.3Å; A473-L477 VanDerWaalsContact O-CG 3.3Å; A473-L477 WeakPolarHBondContact O-CG 3.29Å; A473-L477 PolarHBondContact O-N 3.07Å; L477-L479 VanDerWaalsContact C-N 3.26Å; L477-L479 PolarHBondContact O-N 2.93Å; L477-I480 HydrophobicContact CD2-CD1 4.31Å; L477-I480 PolarHBondContact O-N 3.33Å; L477-T481 PolarHBondContact O-N 3.34Å; L477-T481 VanDerWaalsContact O-N 3.14Å
478	A	97.6	Very high	95.6	Very high	0 Å²	0	47.8 Å²	47.8	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-66.1	-30.8	174.4	0	0	0	0	0	111.8	F303 L306 I370 S474 L475 L476 T481 L482	F303-A478 HydrophobicContact CD2-CB 3.97Å; F303-A478 WeakPolarHBondContact CD2-O 3.45Å; F303-A478 HydrophobicContact CE2-CB 4.18Å; L306-A478 HydrophobicContact CB-CB 3.96Å; L306-A478 HydrophobicContact CD1-CB 4.25Å; I370-A478 HydrophobicContact CD1-CB 4.43Å; S474-A478 WeakPolarHBondContact O-CB 3.41Å; S474-A478 PolarHBondContact O-N 2.88Å; L475-A478 CarbonylContact O-C 3.55Å; L475-A478 WeakPolarHBondContact O-CB 3.39Å; L475-A478 PolarHBondContact O-N 2.94Å; L476-A478 VanDerWaalsContact C-N 3.33Å; A478-T481 WeakPolarHBondContact CA-OG1 3.25Å; A478-T481 PolarHBondContact O-N 3.49Å; A478-T481 PolarHBondContact O-OG1 3.45Å; A478-L482 VanDerWaalsContact O-CB 3.29Å; A478-L482 WeakPolarHBondContact O-CB 3.42Å; A478-L482 PolarHBondContact O-N 2.9Å
479	L	97.7	Very high	95	Very high	42 Å²	42	54.9 Å²	54.9	22%	0.22	29%	0.29	C	S	.	.	H	α-helix	trans	-65.8	-42.2	173.2	-178	58.6	0	0	0	111.3	L367 I370 L475 L476 L477 T481 L482 I483	L367-L479 HydrophobicContact CD1-CD1 3.45Å; L367-L479 VanDerWaalsContact CD1-CD1 3.45Å; I370-L479 HydrophobicContact CD1-CB 4.17Å; I370-L479 HydrophobicContact CD1-CD1 4.31Å; I370-L479 HydrophobicContact CG2-CB 4.24Å; L475-L479 WeakPolarHBondContact O-CB 3.48Å; L475-L479 PolarHBondContact O-N 3.35Å; L476-L479 WeakPolarHBondContact O-CB 3.24Å; L476-L479 PolarHBondContact O-N 2.93Å; L477-L479 VanDerWaalsContact C-N 3.26Å; L477-L479 PolarHBondContact O-N 2.93Å; L479-T481 PolarHBondContact O-N 3.01Å; L479-L482 WeakPolarHBondContact O-CB 3.49Å; L479-L482 PolarHBondContact O-N 3.29Å; L479-I483 HydrophobicContact CD1-CD1 4.19Å; L479-I483 HydrophobicContact CD1-CG1 4.3Å; L479-I483 HydrophobicContact CG-CD1 3.93Å; L479-I483 HydrophobicContact CG-CG1 4.48Å; L479-I483 VanDerWaalsContact O-CG1 3.27Å; L479-I483 WeakPolarHBondContact O-CG1 3.39Å; L479-I483 PolarHBondContact O-N 3.12Å
480	I	97.4	Very high	94.3	Very high	96 Å²	96	53.5 Å²	53.5	49%	0.492	28%	0.279	S	S	.	.	H	α-helix	trans	-60.4	-46.9	176.1	-65.2	168.3	0	0	0	110.1	L476 L477 L482 I483 L484	L476-I480 WeakPolarHBondContact O-CG1 3.38Å; L476-I480 PolarHBondContact O-N 3.36Å; L476-I480 VanDerWaalsContact O-N 3.12Å; L477-I480 HydrophobicContact CD2-CD1 4.31Å; L477-I480 PolarHBondContact O-N 3.33Å; I480-L482 VanDerWaalsContact C-N 3.31Å; I480-L482 PolarHBondContact O-N 3.43Å; I480-I483 PolarHBondContact O-N 3.38Å; I480-L484 HydrophobicContact CG2-CD1 4.22Å; I480-L484 WeakPolarHBondContact O-CG 3.43Å; I480-L484 PolarHBondContact O-N 3.15Å
481	T	95.6	Very high	93.3	Very high	5 Å²	5	51.6 Å²	51.6	3%	0.031	27%	0.273	C	S	.	.	H	α-helix	trans	-63.9	-37.7	177.6	60.3	0	0	0	0	111.9	L302 F303 L477 A478 L479 L484 L485	L302-T481 HydrophobicContact CB-CG2 4.26Å; L302-T481 HydrophobicContact CD2-CG2 3.62Å; L302-T481 HydrophobicContact CG-CG2 3.87Å; F303-T481 WeakPolarHBondContact CD2-OG1 3.46Å; L477-T481 PolarHBondContact O-N 3.34Å; L477-T481 VanDerWaalsContact O-N 3.14Å; A478-T481 WeakPolarHBondContact CA-OG1 3.25Å; A478-T481 PolarHBondContact O-N 3.49Å; A478-T481 PolarHBondContact O-OG1 3.45Å; L479-T481 PolarHBondContact O-N 3.01Å; T481-L484 PolarHBondContact O-N 3.44Å; T481-L485 WeakPolarHBondContact O-CB 3.16Å; T481-L485 VanDerWaalsContact O-CG 3.28Å; T481-L485 WeakPolarHBondContact O-CG 3.41Å; T481-L485 PolarHBondContact O-N 3.25Å
482	L	95.4	Very high	91.9	Very high	1 Å²	1	57 Å²	57	1%	0.005	30%	0.298	C	S	.	.	H	α-helix	trans	-64.4	-40.6	175.3	-174	65.8	0	0	0	112.8	F303 K363 L367 I370 A478 L479 I480 L485 W486	F303-L482 HydrophobicContact CD2-CB 4.37Å; F303-L482 HydrophobicContact CE2-CB 4.02Å; F303-L482 HydrophobicContact CE2-CD1 4.21Å; F303-L482 HydrophobicContact CE2-CG 4.49Å; F303-L482 HydrophobicContact CZ-CD1 4.31Å; K363-L482 HydrophobicContact CB-CD1 4.14Å; K363-L482 HydrophobicContact CG-CD1 4.18Å; L367-L482 HydrophobicContact CB-CD2 4.14Å; I370-L482 HydrophobicContact CD1-CD2 3.93Å; A478-L482 VanDerWaalsContact O-CB 3.29Å; A478-L482 WeakPolarHBondContact O-CB 3.42Å; A478-L482 PolarHBondContact O-N 2.9Å; L479-L482 WeakPolarHBondContact O-CB 3.49Å; L479-L482 PolarHBondContact O-N 3.29Å; I480-L482 VanDerWaalsContact C-N 3.31Å; I480-L482 PolarHBondContact O-N 3.43Å; L482-L485 CarbonylContact O-C 3.54Å; L482-L485 PolarHBondContact O-N 3.32Å; L482-W486 PolarHBondContact O-N 3.49Å
483	I	95.4	Very high	90.1	Very high	101 Å²	101	61.6 Å²	61.6	52%	0.518	33%	0.327	S	S	.	.	H	α-helix	trans	-64.5	-44	176.1	-70.8	165.9	0	0	0	110.3	L479 I480 L485 W486 P487	L479-I483 HydrophobicContact CD1-CD1 4.19Å; L479-I483 HydrophobicContact CD1-CG1 4.3Å; L479-I483 HydrophobicContact CG-CD1 3.93Å; L479-I483 HydrophobicContact CG-CG1 4.48Å; L479-I483 VanDerWaalsContact O-CG1 3.27Å; L479-I483 WeakPolarHBondContact O-CG1 3.39Å; L479-I483 PolarHBondContact O-N 3.12Å; I480-I483 PolarHBondContact O-N 3.38Å; I483-L485 VanDerWaalsContact C-N 3.27Å; I483-L485 PolarHBondContact O-N 3.04Å; I483-W486 WeakPolarHBondContact O-CB 3.42Å; I483-W486 PolarHBondContact O-N 3.03Å; I483-P487 WeakPolarHBondContact O-CD 3.07Å
484	L	94.7	Very high	88.3	Confident	91 Å²	91	60 Å²	60	48%	0.476	31%	0.312	S	S	.	.	H	α-helix	trans	-63.9	-33.1	175.7	-67.4	174.8	0	0	0	112.5	L299 I480 T481 W486 Q488	L299-L484 HydrophobicContact CD1-CB 4.31Å; L299-L484 HydrophobicContact CD2-CB 4.22Å; L299-L484 HydrophobicContact CD2-CD1 3.98Å; I480-L484 HydrophobicContact CG2-CD1 4.22Å; I480-L484 WeakPolarHBondContact O-CG 3.43Å; I480-L484 PolarHBondContact O-N 3.15Å; T481-L484 PolarHBondContact O-N 3.44Å; L484-W486 VanDerWaalsContact C-N 3.34Å; L484-Q488 PolarHBondContact O-NE2 3.4Å
485	L	92.3	Very high	86.3	Confident	1 Å²	1	64.8 Å²	64.8	1%	0.005	34%	0.343	C	S	.	.	H	α-helix	trans	-76.8	-19	173.2	-74.4	169.9	0	0	0	113	L299 I300 K363 T481 L482 I483 Q488	L299-L485 HydrophobicContact CB-CD1 4.15Å; L299-L485 HydrophobicContact CB-CD2 3.75Å; L299-L485 HydrophobicContact CB-CG 3.89Å; L299-L485 HydrophobicContact CD1-CD2 3.89Å; L299-L485 HydrophobicContact CD1-CG 4.19Å; L299-L485 HydrophobicContact CG-CD2 4.49Å; I300-L485 HydrophobicContact CD1-CD2 4.47Å; I300-L485 HydrophobicContact CG1-CD1 3.8Å; I300-L485 HydrophobicContact CG1-CD2 4.01Å; K363-L485 WeakPolarHBondContact CE-O 3.38Å; K363-L485 PolarHBondContact NZ-O 3.23Å; T481-L485 WeakPolarHBondContact O-CB 3.16Å; T481-L485 VanDerWaalsContact O-CG 3.28Å; T481-L485 WeakPolarHBondContact O-CG 3.41Å; T481-L485 PolarHBondContact O-N 3.25Å; L482-L485 CarbonylContact O-C 3.54Å; L482-L485 PolarHBondContact O-N 3.32Å; I483-L485 VanDerWaalsContact C-N 3.27Å; I483-L485 PolarHBondContact O-N 3.04Å; L485-Q488 PolarHBondContact O-N 3.43Å
486	W	91.4	Very high	84.2	Confident	120 Å²	120	68.5 Å²	68.5	46%	0.455	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.8	-49.9	-173.2	-159.1	-84.9	0	0	0	114.3	K363 L364 L482 I483 L484 Q488	K363-W486 HydrophobicContact CB-CD2 4.49Å; K363-W486 HydrophobicContact CB-CE3 3.77Å; K363-W486 HydrophobicContact CB-CH2 4.19Å; K363-W486 HydrophobicContact CB-CZ3 3.61Å; K363-W486 HydrophobicContact CD-CD2 4.46Å; K363-W486 HydrophobicContact CD-CE3 4.38Å; K363-W486 PolarHBondContact NZ-O 3.12Å; L364-W486 HydrophobicContact CB-CH2 4.32Å; L364-W486 HydrophobicContact CD1-CH2 4.46Å; L482-W486 PolarHBondContact O-N 3.49Å; I483-W486 WeakPolarHBondContact O-CB 3.42Å; I483-W486 PolarHBondContact O-N 3.03Å; L484-W486 VanDerWaalsContact C-N 3.34Å; W486-Q488 VanDerWaalsContact C-N 3.27Å; W486-Q488 PolarHBondContact O-N 3.17Å
487	P	89.9	Confident	81.8	Confident	110 Å²	110	67.7 Å²	67.7	71%	0.714	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	-14.5	178.8	30.6	-35.9	0	0	0	113.8	I483	I483-P487 WeakPolarHBondContact O-CD 3.07Å
488	Q	88	Confident	79.2	Confident	50 Å²	50	71.1 Å²	71.1	23%	0.234	37%	0.372	C	S	.	.	S	Bend	trans	-86.3	138.9	-172.4	-54.7	-175.1	16	0	0	111.9	K363 L484 L485 W486	K363-Q488 PolarHBondContact NZ-O 3.28Å; L484-Q488 PolarHBondContact O-NE2 3.4Å; L485-Q488 PolarHBondContact O-N 3.43Å; W486-Q488 VanDerWaalsContact C-N 3.27Å; W486-Q488 PolarHBondContact O-N 3.17Å
489	K	83.1	Confident	76.6	Confident	164 Å²	164	75.7 Å²	75.7	71%	0.713	40%	0.401	S	S	*	.	P	Polyproline II helix	trans	-79.6	117.7	164.9	-69.3	-176.6	-178.1	178	0	108.1	Q296 Q492	Q296-K489 PolarHBondContact NE2-O 3.49Å; K489-Q492 HydrophobicContact CB-CG 4.24Å; K489-Q492 WeakPolarHBondContact O-CG 3.33Å
490	V	82.1	Confident	74	Confident	34 Å²	34	79.9 Å²	79.9	21%	0.206	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.9	138.5	180	-179.1	0	0	0	0	109.5	I300 L410 D413 L414	I300-V490 HydrophobicContact CD1-CG1 3.64Å; I300-V490 HydrophobicContact CD1-CG2 4.45Å; L410-V490 HydrophobicContact CD2-CG2 4.16Å; D413-V490 HydrophobicContact CB-CB 4.37Å; D413-V490 HydrophobicContact CB-CG1 3.69Å; L414-V490 HydrophobicContact CB-CG1 4.42Å
491	G	74.1	Confident	71.2	Confident	12 Å²	12	81.4 Å²	81.4	12%	0.124	44%	0.437	C	S	.	.	T	Hydrogen-bonded Turn	trans	84.4	24.9	177.1	0	0	0	0	0	114.2	D413 N416	D413-G491 WeakPolarHBondContact O-CA 3.44Å; N416-G491 PolarHBondContact ND2-O 3.23Å
492	Q	68	Low	68.5	Low	112 Å²	112	90.3 Å²	90.3	52%	0.523	47%	0.47	S	S	.	.	P	Polyproline II helix	trans	-61.9	149	168.5	-79.1	177.1	-20.5	0	0	110.7	K489	K489-Q492 HydrophobicContact CB-CG 4.24Å; K489-Q492 WeakPolarHBondContact O-CG 3.33Å
493	P	61.2	Low	66	Low	116 Å²	116	103.1 Å²	103.1	75%	0.753	53%	0.527	S	S	*	.	P	Polyproline II helix	trans	-54.9	142.3	174.9	-20.2	30.9	0	0	0	111.2
494	L	59.8	Low	64.6	Low	14 Å²	14	103.2 Å²	103.2	7%	0.073	53%	0.527	C	S	.	.	P	Polyproline II helix	trans	-62.9	136.8	176.4	-71.7	161.5	0	0	0	109.8	V286 H290 W291 N294 D496 I497	V286-L494 HydrophobicContact CB-CD1 4.2Å; V286-L494 HydrophobicContact CG1-CD1 3.22Å; V286-L494 HydrophobicContact CG2-CD1 3.84Å; H290-L494 HydrophobicContact CB-CD1 4.05Å; W291-L494 HydrophobicContact CE3-CD2 4.45Å; N294-L494 HydrophobicContact CB-CD2 3.56Å; N294-L494 WeakPolarHBondContact ND2-CD2 3.41Å; L494-D496 PolarHBondContact O-N 2.87Å; L494-I497 HydrophobicContact CB-CD1 4.43Å; L494-I497 PolarHBondContact O-N 2.73Å
495	P	55.1	Low	63	Low	106 Å²	106	103.8 Å²	103.8	69%	0.688	53%	0.53	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.8	-15.2	-171.4	16.4	-27.3	0	0	0	115.7
496	D	53.3	Low	61.4	Low	79 Å²	79	109.6 Å²	109.6	42%	0.422	56%	0.559	S	S	.	*	T	Hydrogen-bonded Turn	trans	-113.2	22.6	-175.2	-65.4	-8.6	0	0	0	113.6	K293 L494 E498	K293-D496 WeakPolarHBondContact CD-OD2 3.1Å; K293-D496 IonicContact NZ-OD2 2.93Å; K293-D496 PolarHBondContact NZ-OD2 3.46Å; L494-D496 PolarHBondContact O-N 2.87Å; D496-E498 PolarHBondContact O-N 2.73Å
497	I	48.3	Very low	59.6	Low	74 Å²	74	108.9 Å²	108.9	38%	0.379	57%	0.565	S	S	.	*			trans	-81.4	78.5	162.1	-57.5	164.5	0	0	0	106.8	A284 V286 L494	A284-I497 HydrophobicContact CB-CB 4.44Å; A284-I497 HydrophobicContact CB-CG1 4.23Å; A284-I497 HydrophobicContact CB-CG2 3.44Å; A284-I497 VanDerWaalsContact CB-CG2 3.44Å; V286-I497 HydrophobicContact CG2-CD1 4.27Å; L494-I497 HydrophobicContact CB-CD1 4.43Å; L494-I497 PolarHBondContact O-N 2.73Å
498	E	42.6	Very low	57.7	Low	166 Å²	166	108.9 Å²	108.9	78%	0.776	56%	0.556	S	S	*	*			trans	-57.8	124.8	152.2	-79.4	178.2	170	0	0	105.7	D496 V500	D496-E498 PolarHBondContact O-N 2.73Å; E498-V500 PolarHBondContact O-N 3.4Å; E498-V500 VanDerWaalsContact O-N 3.16Å
499	P	44.4	Very low	55.7	Low	95 Å²	95	112.8 Å²	112.8	62%	0.617	58%	0.577	S	S	*	*			trans	-52.6	130.1	161.9	24.8	-29.5	0	0	0	105.2	D501	P499-D501 PolarHBondContact O-N 3.44Å
500	V	41.6	Very low	53.7	Low	130 Å²	130	109.1 Å²	109.1	79%	0.788	57%	0.567	S	S	*	*			trans	-56.7	101.1	170.6	176.7	0	0	0	0	105.3	E498 R502	E498-V500 PolarHBondContact O-N 3.4Å; E498-V500 VanDerWaalsContact O-N 3.16Å; V500-R502 PolarHBondContact O-N 3.19Å
501	D	38.2	Very low	51.5	Low	128 Å²	128	114.9 Å²	114.9	68%	0.684	60%	0.595	S	S	*	*			trans	-61.1	107.7	171.8	-82.5	-26	0	0	0	104.8	P499 F503	P499-D501 PolarHBondContact O-N 3.44Å; D501-F503 PolarHBondContact O-N 3.1Å
502	R	40.6	Very low	49.7	Very low	192 Å²	192	123.5 Å²	123.5	73%	0.725	63%	0.634	S	S	*	*			trans	-61.4	110.1	172.5	-70.9	-173.9	-174.6	-178.8	5.4	106.2	V279 V500	V279-R502 VanDerWaalsContact CG1-NH2 3.29Å; V500-R502 PolarHBondContact O-N 3.19Å
503	F	43	Very low	48	Very low	270 Å²	270	124.5 Å²	124.5	100%	1.184	65%	0.645	S	S	*	*			trans	-87.1	0	152.3	-80	-76.7	0	0	0	108.8	D501	D501-F503 PolarHBondContact O-N 3.1Å

Retrieved 503 of 503 residues in 3773.2 ms (Link to these results)

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