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Kynureninase

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

AlphaFold DB , UniProt , Accession A0A077ZA92, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 787 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M48.6Very low83.8Confident155 Ų15585 Ų8576%0.76449%0.488SS*.  01330-65175.5-165.600107.4T3 A316M1-T3 PolarHBondContact O-N 2.61Å; M1-A316 HydrophobicContact CE-CB 4.19Å
2N53.7Low85Confident179 Ų17977.9 Ų77.996%0.95745%0.448SS*.  trans-7855.7177.4-84.4-3.6000111.5
3T64.7Low85.9Confident59 Ų5979 Ų7936%0.36244%0.444SS..  trans-88.1119.3176.9-39.60000108.5M1 F5M1-T3 PolarHBondContact O-N 2.61Å; T3-F5 HydrophobicContact CG2-CD1 4.46Å; T3-F5 HydrophobicContact CG2-CE1 4.21Å; T3-F5 PolarHBondContact O-N 2.92Å
4T84.5Confident86.7Confident125 Ų12579.8 Ų79.877%0.76744%0.442SS*.  trans-80.3100.3173.3-48.20000108.8Y11T4-Y11 PolarHBondContact O-OH 3.21Å
5F95.5Very high87.4Confident25 Ų2575.6 Ų75.611%0.1142%0.419CS..  trans-73155.5175-64.5-61.5000112.1T3 Y11 L15 A323 Y324 F327T3-F5 HydrophobicContact CG2-CD1 4.46Å; T3-F5 HydrophobicContact CG2-CE1 4.21Å; T3-F5 PolarHBondContact O-N 2.92Å; F5-Y11 HydrophobicContact CB-CE1 4.33Å; F5-Y11 HydrophobicContact CD1-CE1 4.16Å; F5-L15 HydrophobicContact CD1-CD1 4.18Å; F5-L15 HydrophobicContact CE1-CD1 4.28Å; F5-A323 HydrophobicContact CE2-CB 3.92Å; F5-A323 HydrophobicContact CZ-CB 4.37Å; F5-Y324 HydrophobicContact CB-CD2 4.03Å; F5-Y324 HydrophobicContact CB-CE2 4.38Å; F5-Y324 AromaticContact CD1-CD2 3.58Å; F5-Y324 HydrophobicContact CD1-CD2 3.58Å; F5-Y324 HydrophobicContact CD1-CE2 4.36Å; F5-Y324 HydrophobicContact CD1-CG 4.33Å; F5-Y324 HydrophobicContact CD2-CD2 4.4Å; F5-Y324 HydrophobicContact CE1-CD2 4.07Å; F5-Y324 HydrophobicContact CE1-CG 4.38Å; F5-Y324 AromaticContact CG-CD2 3.77Å; F5-Y324 HydrophobicContact CG-CD2 3.77Å; F5-F327 HydrophobicContact CB-CB 4.38Å; F5-F327 HydrophobicContact CB-CD1 3.5Å; F5-F327 VanDerWaalsContact CB-CD1 3.5Å; F5-F327 HydrophobicContact CB-CD2 3.99Å; F5-F327 HydrophobicContact CB-CE1 3.67Å; F5-F327 HydrophobicContact CB-CE2 4.11Å; F5-F327 HydrophobicContact CB-CG 3.67Å; F5-F327 HydrophobicContact CB-CZ 3.96Å; F5-F327 HydrophobicContact CD2-CB 4Å; F5-F327 HydrophobicContact CD2-CG 4.19Å; F5-F327 HydrophobicContact CG-CD1 4.37Å; F5-F327 HydrophobicContact CG-CG 4.35Å; F5-F327 VanDerWaalsContact O-CZ 3.26Å; F5-F327 WeakPolarHBondContact O-CZ 3.37Å
6Q95.5Very high88.1Confident121 Ų12171.5 Ų71.557%0.56540%0.396SS*.  trans-122.6154.5172.4-56.5-179.521.900109.6Y11Q6-Y11 HydrophobicContact CB-CD1 3.85Å; Q6-Y11 HydrophobicContact CB-CD2 4.03Å; Q6-Y11 HydrophobicContact CB-CE1 4.12Å; Q6-Y11 HydrophobicContact CB-CE2 4.3Å; Q6-Y11 HydrophobicContact CB-CG 3.8Å; Q6-Y11 HydrophobicContact CG-CD2 4.29Å; Q6-Y11 HydrophobicContact CG-CE2 4.22Å; Q6-Y11 WeakPolarHBondContact O-CD1 3.28Å
7T93.7Very high88.6Confident66 Ų6674.2 Ų74.241%0.40542%0.415SS..  trans-80.3167.2172.9610000110.7F327 L328 K331T7-F327 HydrophobicContact CG2-CE1 3.92Å; T7-F327 HydrophobicContact CG2-CZ 4.13Å; T7-L328 HydrophobicContact CG2-CD2 4.15Å; T7-K331 HydrophobicContact CG2-CB 3.91Å; T7-K331 HydrophobicContact CG2-CG 4.32Å
8G94.5Very high89Confident31 Ų3177.2 Ų77.232%0.3242%0.423SS..SBendtrans98147.5173.100000115.8A10 Y11 A12G8-A10 VanDerWaalsContact C-N 3.34Å; G8-A10 PolarHBondContact O-N 3.26Å; G8-Y11 PolarHBondContact O-N 3.08Å; G8-A12 PolarHBondContact O-N 3.02Å
9L96.8Very high89.3Confident65 Ų6573.9 Ų73.934%0.3441%0.405SS..Hα-helixtrans-63.3-34.4-174.3-175.962.5000113.6Y11 A12 K13 E394 L398L9-Y11 VanDerWaalsContact C-N 3.35Å; L9-Y11 PolarHBondContact O-N 3.34Å; L9-A12 WeakPolarHBondContact O-CB 3.34Å; L9-A12 PolarHBondContact O-N 3.03Å; L9-K13 HydrophobicContact CG-CD 4.5Å; L9-K13 WeakPolarHBondContact O-CG 3.49Å; L9-K13 PolarHBondContact O-N 3Å; L9-E394 HydrophobicContact CD1-CB 4.45Å; L9-E394 HydrophobicContact CD1-CG 3.86Å; L9-L398 HydrophobicContact CD1-CD2 4.41Å; L9-L398 HydrophobicContact CD1-CG 4.49Å
10A97.3Very high89.6Confident82 Ų8277.4 Ų77.468%0.67842%0.418SS*.Hα-helixtrans-64.1-40.2179.200000112.1G8 K13 E14G8-A10 VanDerWaalsContact C-N 3.34Å; G8-A10 PolarHBondContact O-N 3.26Å; A10-K13 PolarHBondContact O-N 3.37Å; A10-E14 PolarHBondContact O-N 2.87Å
11Y97.4Very high90Very high27 Ų2774 Ų7411%0.10640%0.4CS..Hα-helixtrans-69.9-39.1176.1179.8-105.5000111.7T4 F5 Q6 G8 L9 K13 E14 L15 Y324T4-Y11 PolarHBondContact O-OH 3.21Å; F5-Y11 HydrophobicContact CB-CE1 4.33Å; F5-Y11 HydrophobicContact CD1-CE1 4.16Å; Q6-Y11 HydrophobicContact CB-CD1 3.85Å; Q6-Y11 HydrophobicContact CB-CD2 4.03Å; Q6-Y11 HydrophobicContact CB-CE1 4.12Å; Q6-Y11 HydrophobicContact CB-CE2 4.3Å; Q6-Y11 HydrophobicContact CB-CG 3.8Å; Q6-Y11 HydrophobicContact CG-CD2 4.29Å; Q6-Y11 HydrophobicContact CG-CE2 4.22Å; Q6-Y11 WeakPolarHBondContact O-CD1 3.28Å; G8-Y11 PolarHBondContact O-N 3.08Å; L9-Y11 VanDerWaalsContact C-N 3.35Å; L9-Y11 PolarHBondContact O-N 3.34Å; Y11-K13 VanDerWaalsContact C-N 3.32Å; Y11-K13 PolarHBondContact O-N 2.67Å; Y11-E14 WeakPolarHBondContact O-CB 3.49Å; Y11-E14 PolarHBondContact O-N 2.96Å; Y11-E14 VanDerWaalsContact O-N 3.15Å; Y11-L15 HydrophobicContact CD1-CD1 4Å; Y11-L15 HydrophobicContact CD1-CG 4.34Å; Y11-L15 HydrophobicContact CE1-CD1 3.49Å; Y11-L15 VanDerWaalsContact CE1-CD1 3.49Å; Y11-L15 HydrophobicContact CE1-CD2 4.36Å; Y11-L15 HydrophobicContact CE1-CG 3.91Å; Y11-L15 PolarHBondContact O-N 3.02Å; Y11-Y324 HydrophobicContact CD1-CE2 4.12Å; Y11-Y324 HydrophobicContact CE1-CE2 4.06Å
12A97.7Very high92.2Very high0 Ų070 Ų700%038%0.379CS..Hα-helixtrans-57.7-45.2173.800000111.8G8 L9 E14 L15 D16 Y324 Y393 N397G8-A12 PolarHBondContact O-N 3.02Å; L9-A12 WeakPolarHBondContact O-CB 3.34Å; L9-A12 PolarHBondContact O-N 3.03Å; A12-E14 VanDerWaalsContact C-N 3.34Å; A12-E14 PolarHBondContact O-N 3.22Å; A12-L15 WeakPolarHBondContact O-CB 3.45Å; A12-L15 PolarHBondContact O-N 3.43Å; A12-D16 PolarHBondContact O-N 3.03Å; A12-Y324 HydrophobicContact CB-CE1 4.3Å; A12-Y393 WeakPolarHBondContact O-CB 3.28Å; A12-N397 HydrophobicContact CB-CB 3.75Å
13K97.6Very high94.2Very high92 Ų9267.9 Ų67.940%0.436%0.363SS..Hα-helixtrans-62.5-38174.2-72.5-179.6175.8-1700112.9L9 A10 Y11 D16 T17 E394L9-K13 HydrophobicContact CG-CD 4.5Å; L9-K13 WeakPolarHBondContact O-CG 3.49Å; L9-K13 PolarHBondContact O-N 3Å; A10-K13 PolarHBondContact O-N 3.37Å; Y11-K13 VanDerWaalsContact C-N 3.32Å; Y11-K13 PolarHBondContact O-N 2.67Å; K13-D16 PolarHBondContact O-N 3.19Å; K13-T17 WeakPolarHBondContact O-CG2 3.43Å; K13-T17 PolarHBondContact O-N 3.48Å; K13-E394 WeakPolarHBondContact CE-OE1 3.37Å; K13-E394 VanDerWaalsContact CE-OE2 3.24Å; K13-E394 WeakPolarHBondContact CE-OE2 3.18Å; K13-E394 HydrophobicContact CG-CB 4.4Å; K13-E394 IonicContact NZ-OE1 2.88Å; K13-E394 PolarHBondContact NZ-OE1 2.86Å; K13-E394 IonicContact NZ-OE2 2.99Å
14E97.2Very high95.7Very high90 Ų9066.3 Ų66.342%0.42135%0.351SS..Hα-helixtrans-64-40.9174.2-170.4-17115900111.5A10 Y11 A12 D16 T17 K18A10-E14 PolarHBondContact O-N 2.87Å; Y11-E14 WeakPolarHBondContact O-CB 3.49Å; Y11-E14 PolarHBondContact O-N 2.96Å; Y11-E14 VanDerWaalsContact O-N 3.15Å; A12-E14 VanDerWaalsContact C-N 3.34Å; A12-E14 PolarHBondContact O-N 3.22Å; E14-D16 VanDerWaalsContact C-N 3.33Å; E14-D16 PolarHBondContact O-N 3.43Å; E14-T17 PolarHBondContact O-N 3.49Å; E14-T17 PolarHBondContact O-OG1 3.08Å; E14-K18 PolarHBondContact O-N 3.5Å; E14-K18 WeakPolarHBondContact OE1-CE 3.42Å; E14-K18 IonicContact OE1-NZ 2.61Å; E14-K18 PolarHBondContact OE1-NZ 2.64Å
15L97Very high96.2Very high17 Ų1763 Ų639%0.08933%0.325CS..Hα-helixtrans-61.8-40.5175-72.7176.9000112F5 Y11 A12 T17 K18 D19 Y324 Y393F5-L15 HydrophobicContact CD1-CD1 4.18Å; F5-L15 HydrophobicContact CE1-CD1 4.28Å; Y11-L15 HydrophobicContact CD1-CD1 4Å; Y11-L15 HydrophobicContact CD1-CG 4.34Å; Y11-L15 HydrophobicContact CE1-CD1 3.49Å; Y11-L15 VanDerWaalsContact CE1-CD1 3.49Å; Y11-L15 HydrophobicContact CE1-CD2 4.36Å; Y11-L15 HydrophobicContact CE1-CG 3.91Å; Y11-L15 PolarHBondContact O-N 3.02Å; A12-L15 WeakPolarHBondContact O-CB 3.45Å; A12-L15 PolarHBondContact O-N 3.43Å; L15-T17 VanDerWaalsContact C-N 3.29Å; L15-T17 PolarHBondContact O-N 3.26Å; L15-K18 CarbonylContact O-C 3.43Å; L15-K18 WeakPolarHBondContact O-CA 3.25Å; L15-K18 PolarHBondContact O-N 3.04Å; L15-D19 PolarHBondContact O-N 3.46Å; L15-Y324 HydrophobicContact CD1-CD1 4.48Å; L15-Y324 HydrophobicContact CD1-CD2 4.05Å; L15-Y324 HydrophobicContact CD1-CE1 4.46Å; L15-Y324 HydrophobicContact CD1-CE2 4.05Å; L15-Y324 HydrophobicContact CD1-CG 4.27Å; L15-Y393 HydrophobicContact CB-CD1 3.83Å; L15-Y393 HydrophobicContact CB-CD2 3.89Å; L15-Y393 HydrophobicContact CB-CE1 4.31Å; L15-Y393 HydrophobicContact CB-CE2 4.38Å; L15-Y393 HydrophobicContact CB-CG 3.59Å; L15-Y393 HydrophobicContact CD1-CD1 3.54Å; L15-Y393 HydrophobicContact CD1-CE1 3.94Å; L15-Y393 HydrophobicContact CD1-CG 4.14Å; L15-Y393 HydrophobicContact CG-CD1 4.32Å
16D97.5Very high96.2Very high10 Ų1068.1 Ų68.15%0.05335%0.349CS..Hα-helixtrans-58.4-39.7174.3-80.8-42.5000112.4A12 K13 E14 K18 D19 H22 S392 Y393 E394A12-D16 PolarHBondContact O-N 3.03Å; K13-D16 PolarHBondContact O-N 3.19Å; E14-D16 VanDerWaalsContact C-N 3.33Å; E14-D16 PolarHBondContact O-N 3.43Å; D16-K18 PolarHBondContact O-N 3.13Å; D16-D19 PolarHBondContact O-N 2.67Å; D16-H22 IonicContact OD1-CE1 2.63Å; D16-H22 IonicContact OD1-ND1 2.66Å; D16-H22 PolarHBondContact OD1-ND1 3.43Å; D16-H22 VanDerWaalsContact OD1-ND1 3.08Å; D16-S392 WeakPolarHBondContact OD1-CA 3.44Å; D16-S392 VanDerWaalsContact OD1-CB 3.27Å; D16-S392 WeakPolarHBondContact OD1-CB 3.22Å; D16-Y393 WeakPolarHBondContact OD1-CD2 3.37Å; D16-Y393 PolarHBondContact OD1-N 2.93Å; D16-Y393 PolarHBondContact OD2-N 3.35Å; D16-E394 WeakPolarHBondContact OD2-CB 2.99Å; D16-E394 PolarHBondContact OD2-N 3.28Å
17T96.7Very high96.2Very high117 Ų11765.3 Ų65.372%0.71834%0.338SS*.Hα-helixtrans-66.5-19.6175.7680000114K13 E14 L15K13-T17 WeakPolarHBondContact O-CG2 3.43Å; K13-T17 PolarHBondContact O-N 3.48Å; E14-T17 PolarHBondContact O-N 3.49Å; E14-T17 PolarHBondContact O-OG1 3.08Å; L15-T17 VanDerWaalsContact C-N 3.29Å; L15-T17 PolarHBondContact O-N 3.26Å
18K95.6Very high96.4Very high128 Ų12862.7 Ų62.756%0.55732%0.321SS*.Hα-helixtrans-98.5-8.8178.7-64.3175.1-173.5170.30112.7E14 L15 D16 E20E14-K18 PolarHBondContact O-N 3.5Å; E14-K18 WeakPolarHBondContact OE1-CE 3.42Å; E14-K18 IonicContact OE1-NZ 2.61Å; E14-K18 PolarHBondContact OE1-NZ 2.64Å; L15-K18 CarbonylContact O-C 3.43Å; L15-K18 WeakPolarHBondContact O-CA 3.25Å; L15-K18 PolarHBondContact O-N 3.04Å; D16-K18 PolarHBondContact O-N 3.13Å; K18-E20 PolarHBondContact O-N 3.07Å
19D96.3Very high96.5Very high16 Ų1665.8 Ų65.89%0.08633%0.325CS..  trans-80.2107.2-179.6176.87.5000110.7L15 D16 L21 H22 N317 K321 Y393L15-D19 PolarHBondContact O-N 3.46Å; D16-D19 PolarHBondContact O-N 2.67Å; D19-L21 PolarHBondContact O-N 3.23Å; D19-L21 VanDerWaalsContact O-N 3.08Å; D19-L21 PolarHBondContact OD1-N 2.96Å; D19-H22 HydrophobicContact CB-CB 3.94Å; D19-H22 VanDerWaalsContact O-CB 3.28Å; D19-H22 WeakPolarHBondContact O-CB 3.45Å; D19-H22 PolarHBondContact O-N 2.66Å; D19-H22 PolarHBondContact OD1-N 3.35Å; D19-N317 VanDerWaalsContact CG-ND2 3.28Å; D19-N317 PolarHBondContact OD1-ND2 3.1Å; D19-N317 PolarHBondContact OD2-ND2 3.29Å; D19-K321 WeakPolarHBondContact OD2-CE 3.49Å; D19-K321 IonicContact OD2-NZ 3.24Å; D19-K321 PolarHBondContact OD2-NZ 3.45Å; D19-Y393 HydrophobicContact CB-CD2 4.37Å; D19-Y393 HydrophobicContact CB-CE2 3.88Å
20E95.4Very high96.3Very high143 Ų14364.1 Ų64.167%0.66832%0.316SS*.THydrogen-bonded Turntrans-57.3-23.3177.9-61.2-175.4179.800113.9K18 Q23K18-E20 PolarHBondContact O-N 3.07Å; E20-Q23 PolarHBondContact O-NE2 3.5Å
21L96.7Very high96Very high6 Ų666 Ų663%0.03131%0.311CS..THydrogen-bonded Turntrans-96.9-7-179.8-54.8-168.4000113.3D19 Q23 Y24 L309 N317 A388D19-L21 PolarHBondContact O-N 3.23Å; D19-L21 VanDerWaalsContact O-N 3.08Å; D19-L21 PolarHBondContact OD1-N 2.96Å; L21-Q23 PolarHBondContact O-N 2.9Å; L21-Q23 VanDerWaalsContact O-N 3.16Å; L21-Y24 HydrophobicContact CB-CD2 4.44Å; L21-Y24 HydrophobicContact CD2-CD2 4.35Å; L21-Y24 HydrophobicContact CD2-CE2 4.23Å; L21-Y24 WeakPolarHBondContact O-CB 3.48Å; L21-Y24 PolarHBondContact O-N 3.16Å; L21-L309 HydrophobicContact CD2-CD1 4.12Å; L21-L309 HydrophobicContact CD2-CD2 3.52Å; L21-L309 HydrophobicContact CD2-CG 4.43Å; L21-N317 HydrophobicContact CD1-CB 3.63Å; L21-N317 HydrophobicContact CG-CB 4.33Å; L21-A388 HydrophobicContact CD1-CB 4.3Å
22H96Very high95.6Very high70 Ų7070.7 Ų70.732%0.32435%0.345SS..G310 helixtrans-55.2-38.4-176.1-176.286.4000112.7D16 D19 Y24 R25D16-H22 IonicContact OD1-CE1 2.63Å; D16-H22 IonicContact OD1-ND1 2.66Å; D16-H22 PolarHBondContact OD1-ND1 3.43Å; D16-H22 VanDerWaalsContact OD1-ND1 3.08Å; D19-H22 HydrophobicContact CB-CB 3.94Å; D19-H22 VanDerWaalsContact O-CB 3.28Å; D19-H22 WeakPolarHBondContact O-CB 3.45Å; D19-H22 PolarHBondContact O-N 2.66Å; D19-H22 PolarHBondContact OD1-N 3.35Å; H22-Y24 PolarHBondContact O-N 3.15Å; H22-R25 VanDerWaalsContact O-CB 3.25Å; H22-R25 WeakPolarHBondContact O-CB 3.35Å; H22-R25 PolarHBondContact O-N 2.9Å; H22-R25 VanDerWaalsContact O-N 3.09Å
23Q94.7Very high95.2Very high135 Ų13574.4 Ų74.463%0.63138%0.383SS*.G310 helixtrans-59.2-27.1178.967.5-170.7-37.700114.3E20 L21 R25 E26E20-Q23 PolarHBondContact O-NE2 3.5Å; L21-Q23 PolarHBondContact O-N 2.9Å; L21-Q23 VanDerWaalsContact O-N 3.16Å; Q23-R25 PolarHBondContact O-N 3.2Å; Q23-E26 PolarHBondContact O-N 2.9Å
24Y95.8Very high95Very high27 Ų2772.5 Ų72.511%0.10638%0.376CS..G310 helixtrans-71.8-14.7179.9-71.2-89.3000112.2L21 H22 E26 D27 F28 I305 Q308 L309 L389L21-Y24 HydrophobicContact CB-CD2 4.44Å; L21-Y24 HydrophobicContact CD2-CD2 4.35Å; L21-Y24 HydrophobicContact CD2-CE2 4.23Å; L21-Y24 WeakPolarHBondContact O-CB 3.48Å; L21-Y24 PolarHBondContact O-N 3.16Å; H22-Y24 PolarHBondContact O-N 3.15Å; Y24-E26 PolarHBondContact O-N 2.95Å; Y24-D27 WeakPolarHBondContact CD1-OD2 3.43Å; Y24-D27 VanDerWaalsContact O-CB 3.3Å; Y24-D27 WeakPolarHBondContact O-CB 3.4Å; Y24-D27 PolarHBondContact O-N 3.21Å; Y24-F28 WeakPolarHBondContact O-CD2 3.48Å; Y24-I305 HydrophobicContact CD1-CG2 3.98Å; Y24-I305 HydrophobicContact CE1-CG2 4.2Å; Y24-Q308 PolarHBondContact OH-NE2 2.65Å; Y24-Q308 VanDerWaalsContact OH-NE2 3.1Å; Y24-L309 HydrophobicContact CD1-CD1 4.41Å; Y24-L309 HydrophobicContact CD2-CD1 4.3Å; Y24-L309 HydrophobicContact CD2-CD2 4.49Å; Y24-L309 HydrophobicContact CE1-CD1 4.21Å; Y24-L309 HydrophobicContact CE1-CD2 4.44Å; Y24-L309 HydrophobicContact CE1-CG 4.37Å; Y24-L309 HydrophobicContact CE2-CD1 4.14Å; Y24-L309 HydrophobicContact CE2-CD2 3.63Å; Y24-L309 HydrophobicContact CE2-CG 4.3Å; Y24-L309 HydrophobicContact CG-CD1 4.43Å; Y24-L309 WeakPolarHBondContact OH-CD2 3.26Å; Y24-L389 CarbonylContact C-O 3.55Å; Y24-L389 VanDerWaalsContact C-O 3.26Å
25R95.7Very high95Very high56 Ų5669.1 Ų69.121%0.21136%0.361CS..G310 helixtrans-55.4-39.2174.8178.2177.7165.580.5-3.1111.4H22 Q23 D27 F28 I30 L389 Y390 E395H22-R25 VanDerWaalsContact O-CB 3.25Å; H22-R25 WeakPolarHBondContact O-CB 3.35Å; H22-R25 PolarHBondContact O-N 2.9Å; H22-R25 VanDerWaalsContact O-N 3.09Å; Q23-R25 PolarHBondContact O-N 3.2Å; R25-D27 PolarHBondContact O-N 3.37Å; R25-D27 VanDerWaalsContact O-N 3.16Å; R25-F28 PolarHBondContact O-N 3.24Å; R25-F28 VanDerWaalsContact O-N 3.11Å; R25-I30 HydrophobicContact CG-CD1 4.41Å; R25-L389 WeakPolarHBondContact CA-O 3.07Å; R25-L389 PolarHBondContact N-O 3.07Å; R25-Y390 PolarHBondContact NH1-O 3.05Å; R25-E395 IonicContact CZ-OE1 3.9Å; R25-E395 IonicContact CZ-OE2 3.53Å; R25-E395 VanDerWaalsContact NH1-CD 3.32Å; R25-E395 IonicContact NH1-OE1 2.74Å; R25-E395 PolarHBondContact NH1-OE1 3.43Å; R25-E395 IonicContact NH1-OE2 2.98Å; R25-E395 PolarHBondContact NH1-OE2 3.29Å; R25-E395 VanDerWaalsContact NH1-OE2 3.09Å; R25-E395 IonicContact NH2-OE1 3.14Å; R25-E395 PolarHBondContact NH2-OE1 3.18Å
26E95Very high95Very high131 Ų13169.5 Ų69.561%0.61236%0.361SS*.G310 helixtrans-65.4-14.7177.9-66.6-61.4139.800112.9Q23 Y24 F28 K47Q23-E26 PolarHBondContact O-N 2.9Å; Y24-E26 PolarHBondContact O-N 2.95Å; E26-F28 VanDerWaalsContact C-N 3.28Å; E26-K47 WeakPolarHBondContact O-CE 3.23Å; E26-K47 PolarHBondContact O-NZ 3.4Å
27D96.1Very high95.1Very high63 Ų6369 Ų6934%0.33736%0.358SS..G310 helixtrans-82.7-3.6175.8-64.7-34.1000113.1Y24 R25 S46 K47Y24-D27 WeakPolarHBondContact CD1-OD2 3.43Å; Y24-D27 VanDerWaalsContact O-CB 3.3Å; Y24-D27 WeakPolarHBondContact O-CB 3.4Å; Y24-D27 PolarHBondContact O-N 3.21Å; R25-D27 PolarHBondContact O-N 3.37Å; R25-D27 VanDerWaalsContact O-N 3.16Å; D27-S46 CarbonylContact O-C 3.3Å; D27-S46 VanDerWaalsContact O-CA 3.26Å; D27-S46 WeakPolarHBondContact O-CA 3.38Å; D27-K47 PolarHBondContact O-N 3.17Å
28F97.4Very high95Very high10 Ų1064.4 Ų64.44%0.04433%0.329CS..BIsolated β-bridgetrans-113.1148.2-179-66-93.2000112.3Y24 R25 E26 I30 M44 A45 N237 I305 L389 Y390Y24-F28 WeakPolarHBondContact O-CD2 3.48Å; R25-F28 PolarHBondContact O-N 3.24Å; R25-F28 VanDerWaalsContact O-N 3.11Å; E26-F28 VanDerWaalsContact C-N 3.28Å; F28-I30 HydrophobicContact CB-CD1 4.46Å; F28-I30 HydrophobicContact CB-CG1 4.41Å; F28-I30 PolarHBondContact O-N 2.83Å; F28-M44 HydrophobicContact CB-CB 4.31Å; F28-M44 HydrophobicContact CD1-CB 4Å; F28-M44 WeakPolarHBondContact CD1-O 3.37Å; F28-A45 WeakPolarHBondContact CA-O 3.33Å; F28-N237 HydrophobicContact CE1-CB 4.26Å; F28-N237 WeakPolarHBondContact CE1-ND2 3.29Å; F28-I305 HydrophobicContact CE2-CD1 4.48Å; F28-I305 HydrophobicContact CZ-CD1 4.14Å; F28-L389 HydrophobicContact CE2-CB 3.71Å; F28-L389 HydrophobicContact CE2-CD1 4.25Å; F28-L389 HydrophobicContact CZ-CB 3.96Å; F28-L389 HydrophobicContact CZ-CD1 3.75Å; F28-Y390 HydrophobicContact CB-CD1 4.43Å; F28-Y390 AromaticContact CD1-CD1 3.69Å; F28-Y390 HydrophobicContact CD1-CD1 3.69Å; F28-Y390 HydrophobicContact CD1-CE1 4.09Å; F28-Y390 AromaticContact CD2-CD1 3.89Å; F28-Y390 HydrophobicContact CD2-CD1 3.89Å; F28-Y390 HydrophobicContact CD2-CG 4.35Å; F28-Y390 AromaticContact CE1-CD1 3.84Å; F28-Y390 HydrophobicContact CE1-CD1 3.84Å; F28-Y390 HydrophobicContact CE1-CE1 4.1Å; F28-Y390 HydrophobicContact CE2-CD1 4.06Å; F28-Y390 AromaticContact CG-CD1 3.72Å; F28-Y390 HydrophobicContact CG-CD1 3.72Å; F28-Y390 HydrophobicContact CG-CG 4.23Å; F28-Y390 HydrophobicContact CZ-CD1 4.03Å
29F96.1Very high95.1Very high96 Ų9658.3 Ų58.342%0.42130%0.303SS..  trans-85.298.6175.8-68.2-82.2000110.2M44 A45 K47 V50F29-M44 WeakPolarHBondContact O-CE 3.47Å; F29-A45 HydrophobicContact CD2-CB 4.12Å; F29-A45 WeakPolarHBondContact CD2-O 3.33Å; F29-A45 PolarHBondContact N-O 3.41Å; F29-K47 HydrophobicContact CE1-CG 4.47Å; F29-K47 HydrophobicContact CE2-CB 4.4Å; F29-K47 HydrophobicContact CE2-CG 3.88Å; F29-K47 HydrophobicContact CZ-CG 3.84Å; F29-V50 HydrophobicContact CD2-CG2 4.2Å; F29-V50 HydrophobicContact CE2-CB 4.08Å; F29-V50 HydrophobicContact CE2-CG2 3.53Å; F29-V50 HydrophobicContact CZ-CG2 4.31Å
30I92.5Very high95.1Very high30 Ų3057.6 Ų57.615%0.15430%0.299CS..  trans-115.5135.8177.7-61.5175.2000108.9R25 F28 M44 Y390R25-I30 HydrophobicContact CG-CD1 4.41Å; F28-I30 HydrophobicContact CB-CD1 4.46Å; F28-I30 HydrophobicContact CB-CG1 4.41Å; F28-I30 PolarHBondContact O-N 2.83Å; I30-M44 HydrophobicContact CG1-CE 4.17Å; I30-M44 HydrophobicContact CG1-CG 4.36Å; I30-Y390 HydrophobicContact CD1-CD2 4.12Å; I30-Y390 HydrophobicContact CD1-CG 4.27Å
31Q92Very high95.1Very high122 Ų12252.4 Ų52.457%0.5728%0.278SS*.  trans-71.3141.7-176.2-63.9-59.1-32.500111.4G33 E34Q31-G33 PolarHBondContact O-N 2.85Å; Q31-E34 HydrophobicContact CB-CB 3.92Å; Q31-E34 WeakPolarHBondContact O-CB 3.39Å; Q31-E34 PolarHBondContact O-N 3.49Å; Q31-E34 VanDerWaalsContact O-N 3.08Å
32P88.9Confident95.1Very high125 Ų12554.5 Ų54.581%0.81229%0.289SS*.THydrogen-bonded Turntrans-57.4126.5175-24.233.9000111.8E34P32-E34 VanDerWaalsContact C-N 3.29Å; P32-E34 PolarHBondContact O-N 2.68Å
33G89.5Confident95.1Very high78 Ų7851.4 Ų51.480%0.80428%0.277SS*.THydrogen-bonded Turntrans82.4-0.8-179.600000115.1Q31Q31-G33 PolarHBondContact O-N 2.85Å
34E93Very high95.2Very high53 Ų5346.1 Ų46.125%0.24825%0.252CS..  trans-94.4134.6175.6-172.2179.883.800111.1Q31 P32 G371 V373Q31-E34 HydrophobicContact CB-CB 3.92Å; Q31-E34 WeakPolarHBondContact O-CB 3.39Å; Q31-E34 PolarHBondContact O-N 3.49Å; Q31-E34 VanDerWaalsContact O-N 3.08Å; P32-E34 VanDerWaalsContact C-N 3.29Å; P32-E34 PolarHBondContact O-N 2.68Å; E34-G371 CarbonylContact C-O 3.52Å; E34-G371 WeakPolarHBondContact CA-O 3.47Å; E34-V373 HydrophobicContact CG-CG2 3.75Å
35I97.6Very high95.2Very high19 Ų1947 Ų4710%0.09727%0.265CS..EExtended strand (participates in β ladder)trans-108.9105.7168.8-54.6177.6000108.3M37 G371 V372 V373 E395 L398 V399I35-M37 HydrophobicContact CG2-CG 4.2Å; I35-M37 HydrophobicContact CG2-SD 4.36Å; I35-G371 PolarHBondContact N-O 3.08Å; I35-V372 HydrophobicContact CB-CG2 4.32Å; I35-V372 HydrophobicContact CD1-CG2 4.38Å; I35-V372 WeakPolarHBondContact O-CA 3.45Å; I35-V373 PolarHBondContact O-N 3.37Å; I35-E395 HydrophobicContact CD1-CG 4.48Å; I35-E395 HydrophobicContact CG1-CG 4.18Å; I35-E395 HydrophobicContact CG2-CB 3.7Å; I35-E395 HydrophobicContact CG2-CG 3.94Å; I35-L398 HydrophobicContact CD1-CB 3.73Å; I35-L398 HydrophobicContact CD1-CD1 4.11Å; I35-V399 HydrophobicContact CB-CG2 4.43Å; I35-V399 HydrophobicContact CD1-CG2 4.45Å; I35-V399 HydrophobicContact CG2-CG2 3.63Å
36Y97.4Very high95.3Very high25 Ų2544.3 Ų44.310%0.09826%0.255CS..EExtended strand (participates in β ladder)trans-90.9111.1-173.4-162-92.3000112.4D38 L42 M44 V373 Y390Y36-D38 VanDerWaalsContact CE1-C 3.46Å; Y36-D38 HydrophobicContact CE1-CB 4.11Å; Y36-L42 VanDerWaalsContact CE1-O 3.29Å; Y36-L42 WeakPolarHBondContact CE1-O 3.42Å; Y36-L42 PolarHBondContact OH-O 3.35Å; Y36-M44 HydrophobicContact CD1-CG 3.72Å; Y36-M44 HydrophobicContact CD1-SD 3.43Å; Y36-M44 WeakPolarHBondContact CD1-SD 3.42Å; Y36-M44 HydrophobicContact CD2-CE 4.41Å; Y36-M44 HydrophobicContact CD2-SD 3.58Å; Y36-M44 VanDerWaalsContact CD2-SD 3.58Å; Y36-M44 HydrophobicContact CE1-CG 4.04Å; Y36-M44 HydrophobicContact CE1-SD 3.47Å; Y36-M44 WeakPolarHBondContact CE1-SD 3.24Å; Y36-M44 HydrophobicContact CE2-SD 3.65Å; Y36-M44 HydrophobicContact CG-CG 4.11Å; Y36-M44 HydrophobicContact CG-SD 3.47Å; Y36-M44 VanDerWaalsContact CZ-SD 3.6Å; Y36-V373 HydrophobicContact CD2-CB 3.89Å; Y36-V373 HydrophobicContact CD2-CG1 4.04Å; Y36-V373 HydrophobicContact CD2-CG2 4.16Å; Y36-V373 HydrophobicContact CE2-CB 4.21Å; Y36-V373 HydrophobicContact CE2-CG1 3.82Å; Y36-Y390 HydrophobicContact CD1-CE2 4.2Å
37M97.9Very high95.4Very high0 Ų042.5 Ų42.50%025%0.245CC..  trans-116.716.7-177.4-60.5-68.2-75.900112.8I35 L325 V372 V373 L384 A385 P386 T391 V399I35-M37 HydrophobicContact CG2-CG 4.2Å; I35-M37 HydrophobicContact CG2-SD 4.36Å; M37-L325 HydrophobicContact CE-CD2 4.29Å; M37-V372 HydrophobicContact CG-CG1 4.3Å; M37-V373 CarbonylContact C-O 3.6Å; M37-V373 WeakPolarHBondContact CA-O 3.49Å; M37-V373 WeakPolarHBondContact CB-O 3.23Å; M37-V373 PolarHBondContact N-O 3.21Å; M37-L384 HydrophobicContact CB-CD2 4.12Å; M37-L384 HydrophobicContact CE-CB 4.05Å; M37-L384 HydrophobicContact CG-CD2 4.5Å; M37-A385 WeakPolarHBondContact O-CB 3.34Å; M37-A385 PolarHBondContact O-N 3.33Å; M37-P386 HydrophobicContact CE-CB 4.4Å; M37-P386 HydrophobicContact CE-CG 3.82Å; M37-T391 HydrophobicContact SD-CG2 3.73Å; M37-V399 HydrophobicContact CE-CG2 4.48Å; M37-V399 HydrophobicContact CG-CG2 3.95Å; M37-V399 HydrophobicContact SD-CG2 4.24Å
38D96.6Very high95.4Very high20 Ų2041 Ų4111%0.10724%0.242CC..BIsolated β-bridgetrans-115.425.2-175.3-168.321000113.8Y36 N40 S41 L42 V373 D375Y36-D38 VanDerWaalsContact CE1-C 3.46Å; Y36-D38 HydrophobicContact CE1-CB 4.11Å; D38-N40 PolarHBondContact O-N 3.03Å; D38-N40 VanDerWaalsContact O-N 3.09Å; D38-N40 PolarHBondContact OD1-OD1 2.81Å; D38-S41 VanDerWaalsContact CG-CB 3.49Å; D38-S41 PolarHBondContact O-N 3.23Å; D38-S41 WeakPolarHBondContact OD1-CB 3.44Å; D38-L42 PolarHBondContact O-N 2.8Å; D38-V373 HydrophobicContact CB-CG1 4.19Å; D38-V373 PolarHBondContact N-O 3.23Å; D38-D375 WeakPolarHBondContact OD1-CB 3.35Å
39G97Very high95.4Very high0 Ų040.9 Ų40.90%024%0.242CC..THydrogen-bonded Turntrans-64.2-15.6178.300000114.5S41 L42 K234 Y235 Y390G39-S41 VanDerWaalsContact C-N 3.29Å; G39-L42 WeakPolarHBondContact CA-O 3.34Å; G39-K234 CarbonylContact O-C 3.23Å; G39-Y235 PolarHBondContact O-N 3.02Å; G39-Y390 VanDerWaalsContact CA-OH 3.3Å; G39-Y390 WeakPolarHBondContact CA-OH 3.44Å
40N96.5Very high95.4Very high0 Ų038.5 Ų38.50%024%0.235CC..THydrogen-bonded Turntrans-76-14.2172.464.4-42.1000113D38 H211 K234 Y235 R383 A385D38-N40 PolarHBondContact O-N 3.03Å; D38-N40 VanDerWaalsContact O-N 3.09Å; D38-N40 PolarHBondContact OD1-OD1 2.81Å; N40-H211 PolarHBondContact O-CE1 3.41Å; N40-H211 PolarHBondContact O-ND1 2.94Å; N40-K234 VanDerWaalsContact O-CD 3.27Å; N40-K234 WeakPolarHBondContact O-CD 3.31Å; N40-K234 WeakPolarHBondContact O-CG 3.48Å; N40-Y235 HydrophobicContact CB-CE1 4.01Å; N40-Y235 HydrophobicContact CB-CE2 3.77Å; N40-Y235 WeakPolarHBondContact CB-OH 3.45Å; N40-R383 VanDerWaalsContact ND2-CZ 3.29Å; N40-R383 PolarHBondContact ND2-NH1 3.45Å; N40-A385 HydrophobicContact CB-CB 3.78Å; N40-A385 VanDerWaalsContact OD1-CB 3.31Å; N40-A385 WeakPolarHBondContact OD1-CB 3.3Å
41S95.2Very high95.7Very high34 Ų3439.9 Ų39.924%0.23825%0.245CC..THydrogen-bonded Turntrans-105.7-47.7173.8-1660000111.6D38 G39 Y233 K234D38-S41 VanDerWaalsContact CG-CB 3.49Å; D38-S41 PolarHBondContact O-N 3.23Å; D38-S41 WeakPolarHBondContact OD1-CB 3.44Å; G39-S41 VanDerWaalsContact C-N 3.29Å; S41-Y233 WeakPolarHBondContact O-CD2 3.19Å; S41-Y233 WeakPolarHBondContact O-CE2 3.32Å; S41-K234 VanDerWaalsContact O-CG 3.3Å; S41-K234 WeakPolarHBondContact O-CG 3.42Å
42L96.3Very high95.9Very high50 Ų5034.7 Ų34.726%0.26222%0.223SC..SBendtrans-141.8114.4174-178.964.6000109.8Y36 D38 G39 Y233 L240Y36-L42 VanDerWaalsContact CE1-O 3.29Å; Y36-L42 WeakPolarHBondContact CE1-O 3.42Å; Y36-L42 PolarHBondContact OH-O 3.35Å; D38-L42 PolarHBondContact O-N 2.8Å; G39-L42 WeakPolarHBondContact CA-O 3.34Å; L42-Y233 WeakPolarHBondContact CA-O 3.17Å; L42-Y233 HydrophobicContact CD1-CD2 4.42Å; L42-L240 HydrophobicContact CD1-CD2 4.46Å; L42-L240 HydrophobicContact CD1-CG 4.16Å; L42-L240 HydrophobicContact CD2-CD2 3.77Å; L42-L240 HydrophobicContact CD2-CG 4.09Å
43G96.8Very high96.3Very high6 Ų631.6 Ų31.66%0.06220%0.199CC..PPolyproline II helixtrans-68.6146176.300000112.8Y233 K234 N237G43-Y233 PolarHBondContact N-O 3.3Å; G43-K234 VanDerWaalsContact CA-O 3.24Å; G43-K234 WeakPolarHBondContact CA-O 3.45Å; G43-K234 PolarHBondContact N-O 2.77Å; G43-N237 WeakPolarHBondContact CA-OD1 3.32Å
44M96.6Very high96.7Very high24 Ų2433.2 Ų33.212%0.11819%0.185CC..PPolyproline II helixtrans-67.7142.3179.1-64.3-53.5-69.500111.3F28 F29 I30 Y36 S46 N237 Y390F28-M44 HydrophobicContact CB-CB 4.31Å; F28-M44 HydrophobicContact CD1-CB 4Å; F28-M44 WeakPolarHBondContact CD1-O 3.37Å; F29-M44 WeakPolarHBondContact O-CE 3.47Å; I30-M44 HydrophobicContact CG1-CE 4.17Å; I30-M44 HydrophobicContact CG1-CG 4.36Å; Y36-M44 HydrophobicContact CD1-CG 3.72Å; Y36-M44 HydrophobicContact CD1-SD 3.43Å; Y36-M44 WeakPolarHBondContact CD1-SD 3.42Å; Y36-M44 HydrophobicContact CD2-CE 4.41Å; Y36-M44 HydrophobicContact CD2-SD 3.58Å; Y36-M44 VanDerWaalsContact CD2-SD 3.58Å; Y36-M44 HydrophobicContact CE1-CG 4.04Å; Y36-M44 HydrophobicContact CE1-SD 3.47Å; Y36-M44 WeakPolarHBondContact CE1-SD 3.24Å; Y36-M44 HydrophobicContact CE2-SD 3.65Å; Y36-M44 HydrophobicContact CG-CG 4.11Å; Y36-M44 HydrophobicContact CG-SD 3.47Å; Y36-M44 VanDerWaalsContact CZ-SD 3.6Å; M44-S46 PolarHBondContact O-N 3.24Å; M44-N237 PolarHBondContact N-OD1 3.02Å; M44-N237 WeakPolarHBondContact O-CB 3.45Å; M44-Y390 HydrophobicContact CB-CD1 4.42Å; M44-Y390 HydrophobicContact CB-CE1 4.01Å; M44-Y390 HydrophobicContact CB-CE2 4.39Å; M44-Y390 HydrophobicContact CG-CD2 4.23Å; M44-Y390 HydrophobicContact CG-CE1 4.22Å; M44-Y390 HydrophobicContact CG-CE2 3.71Å; M44-Y390 PolarHBondContact N-OH 2.9Å
45A96.1Very high96.9Very high45 Ų4537.7 Ų37.737%0.37220%0.204SC..PPolyproline II helixtrans-63.2131.1174.800000110.5F28 F29F28-A45 WeakPolarHBondContact CA-O 3.33Å; F29-A45 HydrophobicContact CD2-CB 4.12Å; F29-A45 WeakPolarHBondContact CD2-O 3.33Å; F29-A45 PolarHBondContact N-O 3.41Å
46S96.5Very high96.9Very high0 Ų037.5 Ų37.50%020%0.203CC..BIsolated β-bridgetrans-92.1150.4171.673.20000111.5D27 M44 A48 A49 V50D27-S46 CarbonylContact O-C 3.3Å; D27-S46 VanDerWaalsContact O-CA 3.26Å; D27-S46 WeakPolarHBondContact O-CA 3.38Å; M44-S46 PolarHBondContact O-N 3.24Å; S46-A48 PolarHBondContact O-N 3.39Å; S46-A49 WeakPolarHBondContact O-CB 3.49Å; S46-A49 PolarHBondContact O-N 2.8Å; S46-A49 VanDerWaalsContact O-N 3.12Å; S46-A49 VanDerWaalsContact OG-CB 3.3Å; S46-A49 WeakPolarHBondContact OG-CB 3.4Å; S46-A49 PolarHBondContact OG-N 2.8Å; S46-V50 PolarHBondContact O-N 3.05Å
47K97.4Very high96.9Very high92 Ų9239.4 Ų39.440%0.421%0.214SC..Hα-helixtrans-55.6-37.2171.9-69176.5-179.3168.30111.2E26 D27 F29 T51E26-K47 WeakPolarHBondContact O-CE 3.23Å; E26-K47 PolarHBondContact O-NZ 3.4Å; D27-K47 PolarHBondContact O-N 3.17Å; F29-K47 HydrophobicContact CE1-CG 4.47Å; F29-K47 HydrophobicContact CE2-CB 4.4Å; F29-K47 HydrophobicContact CE2-CG 3.88Å; F29-K47 HydrophobicContact CZ-CG 3.84Å; K47-T51 VanDerWaalsContact O-CB 3.3Å; K47-T51 WeakPolarHBondContact O-CB 3.05Å; K47-T51 PolarHBondContact O-N 3.45Å; K47-T51 PolarHBondContact O-OG1 3.44Å
48A96.6Very high96.9Very high33 Ų3344.4 Ų44.427%0.27324%0.237SC..Hα-helixtrans-65.5-43.6175.500000112.4S46 T51 S52 G301 I305S46-A48 PolarHBondContact O-N 3.39Å; A48-T51 PolarHBondContact O-N 3.15Å; A48-S52 WeakPolarHBondContact O-CB 3.22Å; A48-S52 PolarHBondContact O-N 3.47Å; A48-G301 WeakPolarHBondContact CB-O 3.32Å; A48-I305 HydrophobicContact CB-CD1 4.47Å
49A96.7Very high97Very high6 Ų646.2 Ų46.25%0.0524%0.243CC..Hα-helixtrans-60.9-48.6175.100000111.3S46 T51 S52 I53 G298S46-A49 WeakPolarHBondContact O-CB 3.49Å; S46-A49 PolarHBondContact O-N 2.8Å; S46-A49 VanDerWaalsContact O-N 3.12Å; S46-A49 VanDerWaalsContact OG-CB 3.3Å; S46-A49 WeakPolarHBondContact OG-CB 3.4Å; S46-A49 PolarHBondContact OG-N 2.8Å; A49-T51 PolarHBondContact O-N 3.07Å; A49-S52 WeakPolarHBondContact O-CB 3.49Å; A49-S52 PolarHBondContact O-N 3.01Å; A49-I53 WeakPolarHBondContact O-CG1 3.41Å; A49-I53 PolarHBondContact O-N 3.05Å; A49-G298 WeakPolarHBondContact CA-O 3.09Å; A49-G298 WeakPolarHBondContact CB-O 3.3Å
50V97Very high97Very high46 Ų4653.8 Ų53.828%0.27927%0.271SS..Hα-helixtrans-59.8-48.9177.6174.30000111.2F29 S46 S52 I53 E54F29-V50 HydrophobicContact CD2-CG2 4.2Å; F29-V50 HydrophobicContact CE2-CB 4.08Å; F29-V50 HydrophobicContact CE2-CG2 3.53Å; F29-V50 HydrophobicContact CZ-CG2 4.31Å; S46-V50 PolarHBondContact O-N 3.05Å; V50-S52 VanDerWaalsContact C-N 3.26Å; V50-S52 PolarHBondContact O-N 3.34Å; V50-I53 PolarHBondContact O-N 3.36Å; V50-E54 HydrophobicContact CG1-CG 4.43Å; V50-E54 WeakPolarHBondContact O-CG 3.42Å; V50-E54 PolarHBondContact O-N 3.28Å
51T97.6Very high97Very high59 Ų5960.3 Ų60.336%0.36230%0.3SS..Hα-helixtrans-58.4-38.2177.5-62.60000112K47 A48 A49 K55K47-T51 VanDerWaalsContact O-CB 3.3Å; K47-T51 WeakPolarHBondContact O-CB 3.05Å; K47-T51 PolarHBondContact O-N 3.45Å; K47-T51 PolarHBondContact O-OG1 3.44Å; A48-T51 PolarHBondContact O-N 3.15Å; A49-T51 PolarHBondContact O-N 3.07Å; T51-K55 HydrophobicContact CG2-CD 4.27Å; T51-K55 WeakPolarHBondContact O-CB 3.49Å; T51-K55 VanDerWaalsContact O-CG 3.3Å; T51-K55 WeakPolarHBondContact O-CG 3.29Å; T51-K55 PolarHBondContact O-N 2.87Å
52S97.1Very high97.2Very high14 Ų1467.5 Ų67.510%0.09833%0.327CS..Hα-helixtrans-67.9-41.1179.2-170.30000112.1A48 A49 V50 K55 M56 A297A48-S52 WeakPolarHBondContact O-CB 3.22Å; A48-S52 PolarHBondContact O-N 3.47Å; A49-S52 WeakPolarHBondContact O-CB 3.49Å; A49-S52 PolarHBondContact O-N 3.01Å; V50-S52 VanDerWaalsContact C-N 3.26Å; V50-S52 PolarHBondContact O-N 3.34Å; S52-K55 PolarHBondContact O-N 2.89Å; S52-M56 PolarHBondContact O-N 3.36Å; S52-M56 VanDerWaalsContact O-N 3.1Å; S52-A297 WeakPolarHBondContact CB-O 3.35Å; S52-A297 PolarHBondContact OG-O 3.48Å
53I97.2Very high97.2Very high59 Ų5968 Ų6830%0.30333%0.327SS..Hα-helixtrans-62.8-47.8173.7-64.1170.9000110.6A49 V50 K55 M56 I57 A297A49-I53 WeakPolarHBondContact O-CG1 3.41Å; A49-I53 PolarHBondContact O-N 3.05Å; V50-I53 PolarHBondContact O-N 3.36Å; I53-K55 VanDerWaalsContact C-N 3.34Å; I53-K55 PolarHBondContact O-N 3.31Å; I53-M56 WeakPolarHBondContact O-CB 3.37Å; I53-M56 PolarHBondContact O-N 2.68Å; I53-I57 HydrophobicContact CG2-CD1 3.9Å; I53-I57 HydrophobicContact CG2-CG1 4.42Å; I53-I57 WeakPolarHBondContact O-CG1 3.27Å; I53-I57 PolarHBondContact O-N 3.05Å; I53-A297 HydrophobicContact CG1-CB 4.44Å
54E97.8Very high97.2Very high112 Ų11269.2 Ų69.252%0.52334%0.34SS..Hα-helixtrans-58.5-44.3178.4-72175.7158.200111.9V50 M56 I57 E58V50-E54 HydrophobicContact CG1-CG 4.43Å; V50-E54 WeakPolarHBondContact O-CG 3.42Å; V50-E54 PolarHBondContact O-N 3.28Å; E54-M56 VanDerWaalsContact C-N 3.27Å; E54-M56 PolarHBondContact O-N 3.11Å; E54-I57 WeakPolarHBondContact O-CB 3.44Å; E54-I57 PolarHBondContact O-N 2.77Å; E54-E58 PolarHBondContact O-N 2.98Å
55K97.6Very high97.2Very high147 Ų14773.8 Ų73.864%0.63937%0.37SS*.Hα-helixtrans-57.8-40.9173.8-77.2172.9-179.41740112T51 S52 I53 E58 R59T51-K55 HydrophobicContact CG2-CD 4.27Å; T51-K55 WeakPolarHBondContact O-CB 3.49Å; T51-K55 VanDerWaalsContact O-CG 3.3Å; T51-K55 WeakPolarHBondContact O-CG 3.29Å; T51-K55 PolarHBondContact O-N 2.87Å; S52-K55 PolarHBondContact O-N 2.89Å; I53-K55 VanDerWaalsContact C-N 3.34Å; I53-K55 PolarHBondContact O-N 3.31Å; K55-E58 PolarHBondContact O-N 3.1Å; K55-R59 WeakPolarHBondContact O-CB 3.42Å; K55-R59 PolarHBondContact O-N 2.92Å
56M97.3Very high97.2Very high15 Ų1577.6 Ų77.67%0.07438%0.38CS..Hα-helixtrans-69.9-35.2178.6-167.960.273.700112.4S52 I53 E54 R59 W60 L71 Y74 I293 F294 A297S52-M56 PolarHBondContact O-N 3.36Å; S52-M56 VanDerWaalsContact O-N 3.1Å; I53-M56 WeakPolarHBondContact O-CB 3.37Å; I53-M56 PolarHBondContact O-N 2.68Å; E54-M56 VanDerWaalsContact C-N 3.27Å; E54-M56 PolarHBondContact O-N 3.11Å; M56-R59 WeakPolarHBondContact O-CB 3.39Å; M56-R59 PolarHBondContact O-N 3.44Å; M56-W60 PolarHBondContact O-N 3.24Å; M56-L71 HydrophobicContact CE-CD2 3.76Å; M56-L71 HydrophobicContact SD-CD1 3.88Å; M56-L71 HydrophobicContact SD-CD2 3.9Å; M56-Y74 HydrophobicContact CE-CD1 4.45Å; M56-Y74 HydrophobicContact CE-CE1 3.81Å; M56-Y74 HydrophobicContact CE-CE2 4.19Å; M56-I293 HydrophobicContact CE-CG2 3.74Å; M56-I293 HydrophobicContact CG-CG2 3.5Å; M56-I293 VanDerWaalsContact CG-CG2 3.5Å; M56-I293 HydrophobicContact SD-CG2 3.41Å; M56-I293 WeakPolarHBondContact SD-CG2 3.38Å; M56-F294 HydrophobicContact CB-CD1 4.19Å; M56-F294 HydrophobicContact CB-CE1 4.36Å; M56-F294 HydrophobicContact CG-CD1 3.78Å; M56-F294 HydrophobicContact CG-CE1 3.87Å; M56-A297 HydrophobicContact CB-CB 3.84Å; M56-A297 HydrophobicContact CE-CB 4.22Å; M56-A297 HydrophobicContact CG-CB 4.16Å
57I97.8Very high97.2Very high65 Ų6577.9 Ų77.933%0.33338%0.382SS..Hα-helixtrans-63.9-47.2172.2-69.3167.9000110.5I53 E54 R59 W60 K61 F294I53-I57 HydrophobicContact CG2-CD1 3.9Å; I53-I57 HydrophobicContact CG2-CG1 4.42Å; I53-I57 WeakPolarHBondContact O-CG1 3.27Å; I53-I57 PolarHBondContact O-N 3.05Å; E54-I57 WeakPolarHBondContact O-CB 3.44Å; E54-I57 PolarHBondContact O-N 2.77Å; I57-R59 VanDerWaalsContact C-N 3.29Å; I57-R59 PolarHBondContact O-N 2.92Å; I57-W60 PolarHBondContact O-N 3.31Å; I57-K61 HydrophobicContact CG2-CD 4.05Å; I57-K61 WeakPolarHBondContact O-CG 3.22Å; I57-K61 PolarHBondContact O-N 3.37Å; I57-F294 HydrophobicContact CG1-CD1 4.31Å; I57-F294 HydrophobicContact CG1-CE1 3.98Å
58E98.1Very high97Very high105 Ų10578.2 Ų78.249%0.49138%0.38SS..Hα-helixtrans-63.2-37.3176.8-69.7-52.312800112.1E54 K55 K61 K62E54-E58 PolarHBondContact O-N 2.98Å; K55-E58 PolarHBondContact O-N 3.1Å; E58-K61 PolarHBondContact O-N 3.27Å; E58-K61 IonicContact OE1-NZ 2.72Å; E58-K61 PolarHBondContact OE1-NZ 3.25Å; E58-K61 IonicContact OE2-NZ 3.55Å; E58-K61 PolarHBondContact OE2-NZ 2.95Å; E58-K62 WeakPolarHBondContact O-CB 3.37Å; E58-K62 PolarHBondContact O-N 2.71Å
59R97.3Very high96.8Very high58 Ų5882.7 Ų82.722%0.21940%0.4CS..Hα-helixtrans-59.7-49.4172.5-169.6-179.9-179.4-177.7-0.1111.4K55 M56 I57 K61 K62 E63 D70K55-R59 WeakPolarHBondContact O-CB 3.42Å; K55-R59 PolarHBondContact O-N 2.92Å; M56-R59 WeakPolarHBondContact O-CB 3.39Å; M56-R59 PolarHBondContact O-N 3.44Å; I57-R59 VanDerWaalsContact C-N 3.29Å; I57-R59 PolarHBondContact O-N 2.92Å; R59-K61 PolarHBondContact O-N 2.94Å; R59-K62 PolarHBondContact O-N 3.06Å; R59-E63 HydrophobicContact CG-CG 4.4Å; R59-E63 WeakPolarHBondContact CG-OE1 3.41Å; R59-E63 IonicContact CZ-OE2 2.73Å; R59-E63 IonicContact NE-OE1 3.75Å; R59-E63 PolarHBondContact NE-OE1 2.86Å; R59-E63 IonicContact NE-OE2 3.08Å; R59-E63 PolarHBondContact NE-OE2 3.44Å; R59-E63 IonicContact NH2-OE2 3.42Å; R59-E63 PolarHBondContact NH2-OE2 2.9Å; R59-E63 WeakPolarHBondContact O-CB 3.43Å; R59-E63 PolarHBondContact O-N 2.87Å; R59-D70 IonicContact CZ-OD1 2.93Å; R59-D70 IonicContact CZ-OD2 3.54Å; R59-D70 IonicContact NH1-OD1 2.73Å; R59-D70 PolarHBondContact NH1-OD1 3.21Å; R59-D70 IonicContact NH1-OD2 3.99Å; R59-D70 PolarHBondContact NH1-OD2 2.9Å; R59-D70 VanDerWaalsContact NH2-CG 3.26Å; R59-D70 IonicContact NH2-OD1 3.96Å; R59-D70 PolarHBondContact NH2-OD1 3.17Å; R59-D70 IonicContact NH2-OD2 3.84Å; R59-D70 PolarHBondContact NH2-OD2 3.39Å; R59-D70 VanDerWaalsContact NH2-OD2 3.16Å
60W97.2Very high96.7Very high159 Ų15985.7 Ų85.760%0.60242%0.415SS*.Hα-helixtrans-59.7-45.2177.4177.933.3000112.1M56 I57 K62 G64 F294M56-W60 PolarHBondContact O-N 3.24Å; I57-W60 PolarHBondContact O-N 3.31Å; W60-K62 VanDerWaalsContact C-N 3.29Å; W60-K62 PolarHBondContact O-N 3.47Å; W60-G64 WeakPolarHBondContact O-CA 3.44Å; W60-G64 PolarHBondContact O-N 3.04Å; W60-F294 HydrophobicContact CB-CZ 4.47Å; W60-F294 HydrophobicContact CD2-CZ 4.05Å; W60-F294 HydrophobicContact CE3-CE1 4.44Å; W60-F294 HydrophobicContact CE3-CE2 4.11Å; W60-F294 AromaticContact CE3-CZ 3.45Å; W60-F294 HydrophobicContact CE3-CZ 3.45Å; W60-F294 VanDerWaalsContact CE3-CZ 3.45Å; W60-F294 HydrophobicContact CZ3-CE2 4.13Å; W60-F294 AromaticContact CZ3-CZ 3.93Å; W60-F294 HydrophobicContact CZ3-CZ 3.93Å
61K97.5Very high96.6Very high138 Ų13884 Ų8460%0.640%0.404SS*.Hα-helixtrans-57.8-40.7176.9-73.516765.3-156.80112.5I57 E58 R59I57-K61 HydrophobicContact CG2-CD 4.05Å; I57-K61 WeakPolarHBondContact O-CG 3.22Å; I57-K61 PolarHBondContact O-N 3.37Å; E58-K61 PolarHBondContact O-N 3.27Å; E58-K61 IonicContact OE1-NZ 2.72Å; E58-K61 PolarHBondContact OE1-NZ 3.25Å; E58-K61 IonicContact OE2-NZ 3.55Å; E58-K61 PolarHBondContact OE2-NZ 2.95Å; R59-K61 PolarHBondContact O-N 2.94Å
62K97.9Very high96.4Very high184 Ų18483.4 Ų83.480%0.840%0.396SS*.Hα-helixtrans-82.5-42.2-175.4-174.4-179.1176.2-173.40113.3E58 R59 W60E58-K62 WeakPolarHBondContact O-CB 3.37Å; E58-K62 PolarHBondContact O-N 2.71Å; R59-K62 PolarHBondContact O-N 3.06Å; W60-K62 VanDerWaalsContact C-N 3.29Å; W60-K62 PolarHBondContact O-N 3.47Å
63E97.8Very high96.2Very high60 Ų6085.4 Ų85.428%0.2841%0.405SS..Hα-helixtrans-98.8-23.2-169.5-66.1173.9-156.300113R59 V65 Q66 A67R59-E63 HydrophobicContact CG-CG 4.4Å; R59-E63 WeakPolarHBondContact CG-OE1 3.41Å; R59-E63 IonicContact CZ-OE2 2.73Å; R59-E63 IonicContact NE-OE1 3.75Å; R59-E63 PolarHBondContact NE-OE1 2.86Å; R59-E63 IonicContact NE-OE2 3.08Å; R59-E63 PolarHBondContact NE-OE2 3.44Å; R59-E63 IonicContact NH2-OE2 3.42Å; R59-E63 PolarHBondContact NH2-OE2 2.9Å; R59-E63 WeakPolarHBondContact O-CB 3.43Å; R59-E63 PolarHBondContact O-N 2.87Å; E63-V65 PolarHBondContact O-N 2.76Å; E63-Q66 HydrophobicContact CB-CB 4.33Å; E63-Q66 VanDerWaalsContact O-CB 3.27Å; E63-Q66 WeakPolarHBondContact O-CB 3.07Å; E63-Q66 PolarHBondContact O-N 3.11Å; E63-A67 HydrophobicContact CB-CB 4.01Å
64G96.3Very high96.2Very high32 Ų3283.5 Ų83.533%0.3339%0.394SS..G310 helixtrans54.2-126.8-176.100000111.6W60 Q66 A67W60-G64 WeakPolarHBondContact O-CA 3.44Å; W60-G64 PolarHBondContact O-N 3.04Å; G64-Q66 PolarHBondContact O-N 3.1Å; G64-A67 WeakPolarHBondContact O-CB 3.27Å; G64-A67 PolarHBondContact O-N 3.45Å
65V95.6Very high96.1Very high121 Ų12178.4 Ų78.473%0.73337%0.372SS*.G310 helixtrans-64.7-24.7177.671.40000113.1E63 A67 W68E63-V65 PolarHBondContact O-N 2.76Å; V65-A67 PolarHBondContact O-N 3.46Å; V65-A67 VanDerWaalsContact O-N 3.16Å; V65-W68 WeakPolarHBondContact O-CB 3.42Å; V65-W68 PolarHBondContact O-N 2.91Å
66Q96.8Very high96Very high125 Ų12574.8 Ų74.858%0.58436%0.357SS*.G310 helixtrans-65.5-19.4-179.1-59.1-179.4-3.600112.5E63 G64 W68 N69E63-Q66 HydrophobicContact CB-CB 4.33Å; E63-Q66 VanDerWaalsContact O-CB 3.27Å; E63-Q66 WeakPolarHBondContact O-CB 3.07Å; E63-Q66 PolarHBondContact O-N 3.11Å; G64-Q66 PolarHBondContact O-N 3.1Å; Q66-W68 PolarHBondContact O-N 2.94Å; Q66-N69 VanDerWaalsContact O-CB 3.25Å; Q66-N69 WeakPolarHBondContact O-CB 3.24Å; Q66-N69 PolarHBondContact O-N 3.21Å; Q66-N69 PolarHBondContact O-ND2 3.06Å
67A95.9Very high96Very high5 Ų578.8 Ų78.84%0.04137%0.374CS..G310 helixtrans-61.7-24.8174.500000111.9E63 G64 V65 N69 D70 L71E63-A67 HydrophobicContact CB-CB 4.01Å; G64-A67 WeakPolarHBondContact O-CB 3.27Å; G64-A67 PolarHBondContact O-N 3.45Å; V65-A67 PolarHBondContact O-N 3.46Å; V65-A67 VanDerWaalsContact O-N 3.16Å; A67-N69 PolarHBondContact O-N 3.4Å; A67-D70 VanDerWaalsContact O-OD1 3.07Å; A67-L71 HydrophobicContact CB-CD1 3.6Å; A67-L71 HydrophobicContact CB-CG 4.43Å; A67-L71 WeakPolarHBondContact O-CB 3.43Å; A67-L71 WeakPolarHBondContact O-CG 3.2Å; A67-L71 PolarHBondContact O-N 2.93Å; A67-L71 VanDerWaalsContact O-N 3.1Å
68W94.3Very high96Very high99 Ų9975.7 Ų75.738%0.37536%0.358SS..G310 helixtrans-70.8-2.6173.9-73.5114.4000114.4V65 Q66 D70 L71 Y72 F263 P291 I293V65-W68 WeakPolarHBondContact O-CB 3.42Å; V65-W68 PolarHBondContact O-N 2.91Å; Q66-W68 PolarHBondContact O-N 2.94Å; W68-D70 PolarHBondContact O-N 3.34Å; W68-L71 HydrophobicContact CE3-CB 4.38Å; W68-Y72 WeakPolarHBondContact O-CD1 3.41Å; W68-F263 HydrophobicContact CH2-CZ 4.46Å; W68-F263 HydrophobicContact CZ3-CE1 4.38Å; W68-F263 AromaticContact CZ3-CZ 3.98Å; W68-F263 HydrophobicContact CZ3-CZ 3.98Å; W68-P291 HydrophobicContact CH2-CG 4.34Å; W68-P291 HydrophobicContact CZ3-CG 4.09Å; W68-I293 HydrophobicContact CH2-CG1 4.23Å
69N92.9Very high96Very high127 Ų12770.9 Ų70.968%0.67934%0.336SS*.G310 helixtrans-64-23.6175.4-72.3-20.2000113.1Q66 A67 Y72Q66-N69 VanDerWaalsContact O-CB 3.25Å; Q66-N69 WeakPolarHBondContact O-CB 3.24Å; Q66-N69 PolarHBondContact O-N 3.21Å; Q66-N69 PolarHBondContact O-ND2 3.06Å; A67-N69 PolarHBondContact O-N 3.4Å; N69-Y72 WeakPolarHBondContact O-CE1 3.31Å
70D93.7Very high96Very high69 Ų6970.3 Ų70.337%0.36934%0.343SS..THydrogen-bonded Turntrans-141.2-24.7179.765.9-40.9000112.8R59 A67 W68 Y72 I73R59-D70 IonicContact CZ-OD1 2.93Å; R59-D70 IonicContact CZ-OD2 3.54Å; R59-D70 IonicContact NH1-OD1 2.73Å; R59-D70 PolarHBondContact NH1-OD1 3.21Å; R59-D70 IonicContact NH1-OD2 3.99Å; R59-D70 PolarHBondContact NH1-OD2 2.9Å; R59-D70 VanDerWaalsContact NH2-CG 3.26Å; R59-D70 IonicContact NH2-OD1 3.96Å; R59-D70 PolarHBondContact NH2-OD1 3.17Å; R59-D70 IonicContact NH2-OD2 3.84Å; R59-D70 PolarHBondContact NH2-OD2 3.39Å; R59-D70 VanDerWaalsContact NH2-OD2 3.16Å; A67-D70 VanDerWaalsContact O-OD1 3.07Å; W68-D70 PolarHBondContact O-N 3.34Å; D70-Y72 PolarHBondContact O-N 2.96Å; D70-Y72 VanDerWaalsContact O-N 3.1Å; D70-I73 WeakPolarHBondContact O-CG1 3.41Å; D70-I73 PolarHBondContact O-N 3.27Å
71L94.9Very high96.1Very high10 Ų1064.4 Ų64.45%0.05232%0.324CS..G310 helixtrans-64.5-18.1-179-71.9-180000113.9M56 A67 W68 I73 Y74 I293M56-L71 HydrophobicContact CE-CD2 3.76Å; M56-L71 HydrophobicContact SD-CD1 3.88Å; M56-L71 HydrophobicContact SD-CD2 3.9Å; A67-L71 HydrophobicContact CB-CD1 3.6Å; A67-L71 HydrophobicContact CB-CG 4.43Å; A67-L71 WeakPolarHBondContact O-CB 3.43Å; A67-L71 WeakPolarHBondContact O-CG 3.2Å; A67-L71 PolarHBondContact O-N 2.93Å; A67-L71 VanDerWaalsContact O-N 3.1Å; W68-L71 HydrophobicContact CE3-CB 4.38Å; L71-I73 PolarHBondContact O-N 3.13Å; L71-Y74 HydrophobicContact CD2-CD2 4.24Å; L71-Y74 HydrophobicContact CD2-CG 4.17Å; L71-Y74 WeakPolarHBondContact O-CB 3.2Å; L71-Y74 PolarHBondContact O-N 3.08Å; L71-I293 HydrophobicContact CB-CD1 4.06Å; L71-I293 HydrophobicContact CD1-CG2 4.14Å; L71-I293 HydrophobicContact CD2-CG2 4.42Å; L71-I293 WeakPolarHBondContact O-CD1 3.4Å
72Y92.7Very high96.1Very high48 Ų4857.9 Ų57.919%0.18830%0.295CS..G310 helixtrans-64.5-25.617776.9-86.9000113.2W68 N69 D70 N267 F271W68-Y72 WeakPolarHBondContact O-CD1 3.41Å; N69-Y72 WeakPolarHBondContact O-CE1 3.31Å; D70-Y72 PolarHBondContact O-N 2.96Å; D70-Y72 VanDerWaalsContact O-N 3.1Å; Y72-N267 HydrophobicContact CE2-CB 4.08Å; Y72-F271 AromaticContact CD1-CE2 3.94Å; Y72-F271 HydrophobicContact CD1-CE2 3.94Å; Y72-F271 HydrophobicContact CD1-CZ 4.2Å; Y72-F271 AromaticContact CD2-CE2 3.73Å; Y72-F271 HydrophobicContact CD2-CE2 3.73Å; Y72-F271 HydrophobicContact CD2-CZ 4.16Å; Y72-F271 HydrophobicContact CE1-CE2 4.1Å; Y72-F271 AromaticContact CE2-CE2 3.86Å; Y72-F271 HydrophobicContact CE2-CE2 3.86Å; Y72-F271 AromaticContact CG-CE2 3.72Å; Y72-F271 HydrophobicContact CG-CE2 3.72Å; Y72-F271 AromaticContact CG-CZ 3.83Å; Y72-F271 HydrophobicContact CG-CZ 3.83Å
73I94.4Very high96.1Very high56 Ų5649.4 Ų49.429%0.28726%0.259SS..G310 helixtrans-99.811.7172.757.3172.7000113D70 L71 G75 E76 N267D70-I73 WeakPolarHBondContact O-CG1 3.41Å; D70-I73 PolarHBondContact O-N 3.27Å; L71-I73 PolarHBondContact O-N 3.13Å; I73-G75 PolarHBondContact O-N 3.05Å; I73-G75 VanDerWaalsContact O-N 3.13Å; I73-E76 HydrophobicContact CB-CG 4.36Å; I73-E76 WeakPolarHBondContact O-CB 3.44Å; I73-E76 PolarHBondContact O-N 2.93Å; I73-N267 HydrophobicContact CG2-CB 4.33Å; I73-N267 WeakPolarHBondContact CG2-ND2 3.25Å
74Y96.3Very high96.1Very high19 Ų1950.2 Ų50.28%0.07527%0.27CS..Hα-helixtrans-59.5-29.9-175.9-171.6-126.5000112.7M56 L71 E76 K77 I78 I293 M296 A297 E300M56-Y74 HydrophobicContact CE-CD1 4.45Å; M56-Y74 HydrophobicContact CE-CE1 3.81Å; M56-Y74 HydrophobicContact CE-CE2 4.19Å; L71-Y74 HydrophobicContact CD2-CD2 4.24Å; L71-Y74 HydrophobicContact CD2-CG 4.17Å; L71-Y74 WeakPolarHBondContact O-CB 3.2Å; L71-Y74 PolarHBondContact O-N 3.08Å; Y74-E76 PolarHBondContact O-N 3.32Å; Y74-K77 HydrophobicContact CD2-CD 4.19Å; Y74-K77 HydrophobicContact CE2-CD 3.86Å; Y74-K77 WeakPolarHBondContact O-CB 3.47Å; Y74-K77 PolarHBondContact O-N 3.08Å; Y74-K77 VanDerWaalsContact O-N 3.13Å; Y74-I78 HydrophobicContact CE1-CD1 4.22Å; Y74-I78 PolarHBondContact O-N 3.13Å; Y74-I293 HydrophobicContact CD1-CD1 3.91Å; Y74-I293 HydrophobicContact CG-CD1 4.34Å; Y74-M296 HydrophobicContact CD1-CB 3.67Å; Y74-M296 HydrophobicContact CD1-CG 4.44Å; Y74-M296 HydrophobicContact CD1-SD 3.89Å; Y74-M296 HydrophobicContact CE1-CB 3.49Å; Y74-M296 VanDerWaalsContact CE1-CB 3.49Å; Y74-A297 WeakPolarHBondContact OH-CA 3.28Å; Y74-E300 WeakPolarHBondContact CE2-OE2 3.37Å; Y74-E300 VanDerWaalsContact CZ-OE2 3.29Å; Y74-E300 PolarHBondContact OH-OE2 2.72Å
75G95.5Very high96.2Very high5 Ų549 Ų495%0.05226%0.255CS..Hα-helixtrans-54.6-36.7172.700000113.5I73 K77 I78 S79I73-G75 PolarHBondContact O-N 3.05Å; I73-G75 VanDerWaalsContact O-N 3.13Å; G75-K77 VanDerWaalsContact C-N 3.31Å; G75-K77 PolarHBondContact O-N 3.18Å; G75-I78 PolarHBondContact O-N 3.45Å; G75-I78 VanDerWaalsContact O-N 3.12Å; G75-S79 PolarHBondContact O-N 2.8Å; G75-S79 PolarHBondContact O-OG 2.63Å
76E95.6Very high96.4Very high70 Ų7043.2 Ų43.233%0.32722%0.221SC..Hα-helixtrans-63.4-37.8179-61.3-178.3-178.600112.1I73 Y74 I78 S79 A80 N267I73-E76 HydrophobicContact CB-CG 4.36Å; I73-E76 WeakPolarHBondContact O-CB 3.44Å; I73-E76 PolarHBondContact O-N 2.93Å; Y74-E76 PolarHBondContact O-N 3.32Å; E76-I78 VanDerWaalsContact C-N 3.34Å; E76-S79 PolarHBondContact O-N 2.7Å; E76-A80 WeakPolarHBondContact O-CB 3.21Å; E76-A80 PolarHBondContact O-N 3.05Å; E76-N267 PolarHBondContact OE1-ND2 3.45Å
77K96.9Very high96.4Very high100 Ų10039.6 Ų39.644%0.43521%0.205SC..Hα-helixtrans-64-42.3175.1-174.3-173.2177.2-167.10110.7Y74 G75 A80 L81 E300Y74-K77 HydrophobicContact CD2-CD 4.19Å; Y74-K77 HydrophobicContact CE2-CD 3.86Å; Y74-K77 WeakPolarHBondContact O-CB 3.47Å; Y74-K77 PolarHBondContact O-N 3.08Å; Y74-K77 VanDerWaalsContact O-N 3.13Å; G75-K77 VanDerWaalsContact C-N 3.31Å; G75-K77 PolarHBondContact O-N 3.18Å; K77-A80 PolarHBondContact O-N 3.37Å; K77-L81 WeakPolarHBondContact O-CG 3.5Å; K77-L81 PolarHBondContact O-N 3.2Å; K77-E300 VanDerWaalsContact CE-OE1 3.31Å; K77-E300 WeakPolarHBondContact CE-OE1 3.37Å; K77-E300 IonicContact NZ-OE1 3.18Å; K77-E300 PolarHBondContact NZ-OE1 2.63Å; K77-E300 IonicContact NZ-OE2 3.83Å; K77-E300 PolarHBondContact NZ-OE2 2.88Å
78I97.9Very high96.5Very high0 Ų039.8 Ų39.80%021%0.207CC..Hα-helixtrans-69.4-43.2178.1-49.9-53.6000110.5Y74 G75 E76 A80 L81 M82 V95 M296 L299 E300 L303Y74-I78 HydrophobicContact CE1-CD1 4.22Å; Y74-I78 PolarHBondContact O-N 3.13Å; G75-I78 PolarHBondContact O-N 3.45Å; G75-I78 VanDerWaalsContact O-N 3.12Å; E76-I78 VanDerWaalsContact C-N 3.34Å; I78-A80 VanDerWaalsContact C-N 3.26Å; I78-A80 PolarHBondContact O-N 3.13Å; I78-L81 CarbonylContact O-C 3.53Å; I78-L81 WeakPolarHBondContact O-CA 3.31Å; I78-L81 WeakPolarHBondContact O-CB 3.37Å; I78-L81 PolarHBondContact O-N 3.45Å; I78-M82 HydrophobicContact CG2-CG 4.44Å; I78-M82 HydrophobicContact CG2-SD 4.47Å; I78-M82 WeakPolarHBondContact O-CG 3.35Å; I78-M82 PolarHBondContact O-N 2.79Å; I78-V95 HydrophobicContact CB-CB 4.49Å; I78-V95 HydrophobicContact CB-CG2 4.12Å; I78-V95 HydrophobicContact CG2-CB 4.33Å; I78-V95 HydrophobicContact CG2-CG1 4.18Å; I78-V95 HydrophobicContact CG2-CG2 3.82Å; I78-M296 HydrophobicContact CD1-CB 4.42Å; I78-M296 HydrophobicContact CG1-CB 4Å; I78-M296 HydrophobicContact CG1-CG 4.25Å; I78-M296 HydrophobicContact CG1-SD 4.43Å; I78-L299 HydrophobicContact CG2-CD2 3.71Å; I78-L299 HydrophobicContact CG2-CG 4.13Å; I78-E300 HydrophobicContact CD1-CB 3.74Å; I78-E300 HydrophobicContact CD1-CG 4.28Å; I78-L303 HydrophobicContact CG2-CD1 3.84Å
79S98.1Very high96.7Very high3 Ų339.6 Ų39.62%0.02121%0.208CC..Hα-helixtrans-55.3-41.1173.4-680000112G75 E76 L81 M82 A83 I93G75-S79 PolarHBondContact O-N 2.8Å; G75-S79 PolarHBondContact O-OG 2.63Å; E76-S79 PolarHBondContact O-N 2.7Å; S79-L81 VanDerWaalsContact C-N 3.34Å; S79-L81 PolarHBondContact O-N 2.95Å; S79-M82 PolarHBondContact O-N 3Å; S79-A83 PolarHBondContact O-N 3.19Å; S79-I93 WeakPolarHBondContact CB-O 3.47Å; S79-I93 PolarHBondContact OG-O 2.87Å
80A98.2Very high97Very high46 Ų4635.9 Ų35.938%0.3819%0.191SC..Hα-helixtrans-64.5-35.7175.300000113.2E76 K77 I78 M82 P84 P90E76-A80 WeakPolarHBondContact O-CB 3.21Å; E76-A80 PolarHBondContact O-N 3.05Å; K77-A80 PolarHBondContact O-N 3.37Å; I78-A80 VanDerWaalsContact C-N 3.26Å; I78-A80 PolarHBondContact O-N 3.13Å; A80-M82 VanDerWaalsContact C-N 3.34Å; A80-P84 WeakPolarHBondContact O-CD 3.32Å; A80-P90 HydrophobicContact CB-CB 4.19Å; A80-P90 HydrophobicContact CB-CG 4.25Å
81L98.2Very high97.2Very high36 Ų3637.2 Ų37.219%0.18820%0.195CC..Hα-helixtrans-74.4-24174.4-69172.2000112.9K77 I78 S79 E300 L303 N307K77-L81 WeakPolarHBondContact O-CG 3.5Å; K77-L81 PolarHBondContact O-N 3.2Å; I78-L81 CarbonylContact O-C 3.53Å; I78-L81 WeakPolarHBondContact O-CA 3.31Å; I78-L81 WeakPolarHBondContact O-CB 3.37Å; I78-L81 PolarHBondContact O-N 3.45Å; S79-L81 VanDerWaalsContact C-N 3.34Å; S79-L81 PolarHBondContact O-N 2.95Å; L81-E300 HydrophobicContact CD1-CG 3.8Å; L81-L303 HydrophobicContact CB-CB 3.99Å; L81-L303 HydrophobicContact CB-CD1 3.79Å; L81-L303 HydrophobicContact CD1-CB 4.4Å; L81-N307 PolarHBondContact O-ND2 3.28Å
82M98.3Very high97.4Very high1 Ų137 Ų371%0.00519%0.194CC..Hα-helixtrans-84.6-29.6175.7-68-170.1120.200113.1I78 S79 A80 P84 L85 I93 V95 W230 T232 L236 L299 L303I78-M82 HydrophobicContact CG2-CG 4.44Å; I78-M82 HydrophobicContact CG2-SD 4.47Å; I78-M82 WeakPolarHBondContact O-CG 3.35Å; I78-M82 PolarHBondContact O-N 2.79Å; S79-M82 PolarHBondContact O-N 3Å; A80-M82 VanDerWaalsContact C-N 3.34Å; M82-P84 VanDerWaalsContact C-CD 3.49Å; M82-P84 VanDerWaalsContact C-N 3.33Å; M82-L85 VanDerWaalsContact O-CB 3.25Å; M82-L85 WeakPolarHBondContact O-CB 3.46Å; M82-L85 PolarHBondContact O-N 2.84Å; M82-I93 HydrophobicContact CB-CD1 4.25Å; M82-I93 HydrophobicContact CB-CG2 4.42Å; M82-V95 HydrophobicContact SD-CG2 3.46Å; M82-V95 WeakPolarHBondContact SD-CG2 3.41Å; M82-W230 HydrophobicContact SD-CZ2 4.21Å; M82-T232 HydrophobicContact CE-CG2 3.36Å; M82-L236 HydrophobicContact CE-CD1 3.79Å; M82-L299 HydrophobicContact CE-CD2 4.1Å; M82-L303 HydrophobicContact CG-CD1 3.6Å; M82-L303 HydrophobicContact CG-CD2 4.29Å
83A98.4Very high97.6Very high5 Ų534.7 Ų34.74%0.04119%0.185CC..Hα-helixtrans-51.1-41.6-175.600000114.7S79 L85 I86 N87 A88 P90 I93S79-A83 PolarHBondContact O-N 3.19Å; A83-L85 VanDerWaalsContact C-N 3.25Å; A83-L85 PolarHBondContact O-N 3.46Å; A83-I86 PolarHBondContact O-N 3.3Å; A83-N87 PolarHBondContact O-N 3.42Å; A83-N87 VanDerWaalsContact O-N 3.07Å; A83-A88 PolarHBondContact O-N 2.92Å; A83-P90 HydrophobicContact CB-CB 4.42Å; A83-P90 HydrophobicContact CB-CG 3.88Å; A83-I93 VanDerWaalsContact CA-CD1 3.47Å; A83-I93 HydrophobicContact CB-CD1 3.94Å
84P98.1Very high97.8Very high77 Ų7732.1 Ų32.150%0.517%0.172SC..Hα-helixtrans-66.2-21.1176.5-25.839.1000114.8A80 M82 I86 N307A80-P84 WeakPolarHBondContact O-CD 3.32Å; M82-P84 VanDerWaalsContact C-CD 3.49Å; M82-P84 VanDerWaalsContact C-N 3.33Å; P84-I86 VanDerWaalsContact C-N 3.34Å; P84-N307 WeakPolarHBondContact CG-OD1 3.17Å
85L98.2Very high97.9Very high6 Ų631.2 Ų31.23%0.03117%0.168CC..Hα-helixtrans-71.7-28.7-179.3-58.6178.3000113.2M82 A83 I213 L236 L303 F306 M311M82-L85 VanDerWaalsContact O-CB 3.25Å; M82-L85 WeakPolarHBondContact O-CB 3.46Å; M82-L85 PolarHBondContact O-N 2.84Å; A83-L85 VanDerWaalsContact C-N 3.25Å; A83-L85 PolarHBondContact O-N 3.46Å; L85-I213 HydrophobicContact CB-CD1 3.74Å; L85-I213 HydrophobicContact CD1-CD1 4.21Å; L85-I213 HydrophobicContact CD1-CG1 4.31Å; L85-L236 HydrophobicContact CD1-CD1 4.09Å; L85-L236 HydrophobicContact CD1-CD2 3.7Å; L85-L303 HydrophobicContact CD1-CD2 3.65Å; L85-F306 HydrophobicContact CD2-CB 4Å; L85-F306 HydrophobicContact CD2-CD1 4.17Å; L85-F306 HydrophobicContact CD2-CG 4.39Å; L85-M311 HydrophobicContact CD2-CG 3.87Å; L85-M311 HydrophobicContact CD2-SD 3.91Å
86I98.2Very high97.9Very high0 Ų031.7 Ų31.70%017%0.17CC..Hα-helixtrans-119.38.2-179.258.2168.5000113A83 P84 A88 I93 L209 I213 I218 F220 W230 Y247A83-I86 PolarHBondContact O-N 3.3Å; P84-I86 VanDerWaalsContact C-N 3.34Å; I86-A88 VanDerWaalsContact C-N 3.26Å; I86-A88 HydrophobicContact CD1-CB 3.85Å; I86-A88 HydrophobicContact CG1-CB 3.86Å; I86-A88 PolarHBondContact O-N 2.99Å; I86-I93 HydrophobicContact CD1-CD1 3.69Å; I86-I93 HydrophobicContact CD1-CG1 3.99Å; I86-I93 HydrophobicContact CG1-CD1 4.04Å; I86-L209 HydrophobicContact CG2-CD1 4Å; I86-I213 HydrophobicContact CG2-CD1 3.39Å; I86-I218 CarbonylContact C-O 3.57Å; I86-I218 WeakPolarHBondContact CA-O 3.4Å; I86-I218 HydrophobicContact CB-CB 4.42Å; I86-I218 HydrophobicContact CB-CG2 4.02Å; I86-I218 HydrophobicContact CG2-CB 4.16Å; I86-I218 HydrophobicContact CG2-CD1 4.2Å; I86-I218 HydrophobicContact CG2-CG2 3.94Å; I86-F220 HydrophobicContact CB-CD2 4.11Å; I86-F220 HydrophobicContact CB-CE2 4.35Å; I86-F220 HydrophobicContact CB-CG 4.27Å; I86-F220 HydrophobicContact CD1-CD2 3.66Å; I86-F220 HydrophobicContact CD1-CE2 3.87Å; I86-F220 HydrophobicContact CG1-CD2 4.32Å; I86-F220 WeakPolarHBondContact O-CB 3.47Å; I86-F220 PolarHBondContact O-N 2.86Å; I86-W230 HydrophobicContact CD1-CH2 3.84Å; I86-W230 HydrophobicContact CD1-CZ3 4.32Å; I86-Y247 HydrophobicContact CD1-CD2 4.04Å; I86-Y247 HydrophobicContact CD1-CG 4.48Å
87N98.1Very high97.9Very high50 Ų5030 Ų3027%0.26717%0.171SC..THydrogen-bonded Turntrans47.343.1-173.9-163.218.4000114.1A83 D219 K221A83-N87 PolarHBondContact O-N 3.42Å; A83-N87 VanDerWaalsContact O-N 3.07Å; N87-D219 HydrophobicContact CB-CB 4.44Å; N87-D219 PolarHBondContact ND2-OD1 3.46Å; N87-D219 PolarHBondContact ND2-OD2 3.48Å; N87-K221 WeakPolarHBondContact O-CD 3.2Å; N87-K221 WeakPolarHBondContact O-CE 3.48Å; N87-K221 WeakPolarHBondContact O-CG 3.43Å; N87-K221 PolarHBondContact O-N 3.31Å; N87-K221 PolarHBondContact OD1-NZ 2.79Å
88A98.1Very high98Very high8 Ų828.2 Ų28.27%0.06617%0.172CC..  trans-106.1176.3176.500000111.5A83 I86 I93 F220 Y247A83-A88 PolarHBondContact O-N 2.92Å; I86-A88 VanDerWaalsContact C-N 3.26Å; I86-A88 HydrophobicContact CD1-CB 3.85Å; I86-A88 HydrophobicContact CG1-CB 3.86Å; I86-A88 PolarHBondContact O-N 2.99Å; A88-I93 HydrophobicContact CB-CD1 4.43Å; A88-F220 HydrophobicContact CB-CB 4.35Å; A88-Y247 HydrophobicContact CB-CD2 4.1Å; A88-Y247 HydrophobicContact CB-CE2 3.76Å
89K98.3Very high97.9Very high95 Ų9528.7 Ų28.741%0.41318%0.175SC..  trans-79.8146.5166.9-63176.7-178.4176.30109.9Q91 E92K89-Q91 PolarHBondContact O-N 2.85Å; K89-Q91 VanDerWaalsContact O-N 3.15Å; K89-E92 HydrophobicContact CB-CG 4.16Å; K89-E92 WeakPolarHBondContact CB-OE2 3.48Å; K89-E92 PolarHBondContact N-OE2 3.15Å; K89-E92 WeakPolarHBondContact O-CB 3.47Å; K89-E92 PolarHBondContact O-N 2.9Å
90P98.3Very high97.9Very high49 Ų4930.5 Ų30.532%0.31819%0.186SC..G310 helixtrans-53.4-34.9173.7-27.535.6000113.8A80 A83 E92 I93A80-P90 HydrophobicContact CB-CB 4.19Å; A80-P90 HydrophobicContact CB-CG 4.25Å; A83-P90 HydrophobicContact CB-CB 4.42Å; A83-P90 HydrophobicContact CB-CG 3.88Å; P90-E92 PolarHBondContact O-N 3.01Å; P90-I93 PolarHBondContact O-N 3.3Å; P90-I93 VanDerWaalsContact O-N 3.14Å; P90-I93 VanDerWaalsContact O-O 3.13Å
91Q98.2Very high97.8Very high97 Ų9730.2 Ų30.245%0.45318%0.181SC..G310 helixtrans-65.4-21.6178.3-67.276.522.200113.1K89 I93 F253 D282 A283K89-Q91 PolarHBondContact O-N 2.85Å; K89-Q91 VanDerWaalsContact O-N 3.15Å; Q91-I93 PolarHBondContact O-N 3.16Å; Q91-F253 HydrophobicContact CB-CE2 4.33Å; Q91-F253 HydrophobicContact CB-CZ 4.41Å; Q91-F253 WeakPolarHBondContact O-CZ 3.44Å; Q91-D282 HydrophobicContact CB-CB 3.89Å; Q91-D282 HydrophobicContact CG-CB 4.4Å; Q91-D282 WeakPolarHBondContact O-CB 3.43Å; Q91-A283 WeakPolarHBondContact O-CB 3.44Å; Q91-A283 PolarHBondContact O-N 3.24Å
92E98.7Very high97.8Very high5 Ų528.8 Ų28.82%0.02317%0.173CC..G310 helixtrans-84.8-0177.8-62.5175.2118.500112.3K89 P90 Y247 I248 Q250 F253K89-E92 HydrophobicContact CB-CG 4.16Å; K89-E92 WeakPolarHBondContact CB-OE2 3.48Å; K89-E92 PolarHBondContact N-OE2 3.15Å; K89-E92 WeakPolarHBondContact O-CB 3.47Å; K89-E92 PolarHBondContact O-N 2.9Å; P90-E92 PolarHBondContact O-N 3.01Å; E92-Y247 HydrophobicContact CB-CD2 3.7Å; E92-Y247 HydrophobicContact CB-CE2 3.44Å; E92-Y247 VanDerWaalsContact CB-CE2 3.44Å; E92-Y247 HydrophobicContact CG-CE2 4.21Å; E92-Y247 CarbonylContact O-C 3.19Å; E92-Y247 WeakPolarHBondContact O-CA 3.4Å; E92-Y247 VanDerWaalsContact O-CD2 3.29Å; E92-Y247 WeakPolarHBondContact O-CD2 3.41Å; E92-I248 WeakPolarHBondContact CA-O 3.4Å; E92-I248 WeakPolarHBondContact CB-O 3.11Å; E92-I248 PolarHBondContact O-N 3.18Å; E92-Q250 HydrophobicContact CG-CB 3.97Å; E92-Q250 WeakPolarHBondContact OE1-CB 3.38Å; E92-Q250 WeakPolarHBondContact OE1-CG 3.2Å; E92-Q250 PolarHBondContact OE1-N 3.42Å; E92-F253 HydrophobicContact CB-CZ 4.37Å; E92-F253 HydrophobicContact CG-CZ 3.8Å
93I98.6Very high97.8Very high0 Ų028.7 Ų28.70%017%0.173CC..EExtended strand (participates in β ladder)trans-123.3134.4-175.8-54.6171000109.7S79 M82 A83 I86 A88 P90 Q91 V95 W230 L246 Y247S79-I93 WeakPolarHBondContact CB-O 3.47Å; S79-I93 PolarHBondContact OG-O 2.87Å; M82-I93 HydrophobicContact CB-CD1 4.25Å; M82-I93 HydrophobicContact CB-CG2 4.42Å; A83-I93 VanDerWaalsContact CA-CD1 3.47Å; A83-I93 HydrophobicContact CB-CD1 3.94Å; I86-I93 HydrophobicContact CD1-CD1 3.69Å; I86-I93 HydrophobicContact CD1-CG1 3.99Å; I86-I93 HydrophobicContact CG1-CD1 4.04Å; A88-I93 HydrophobicContact CB-CD1 4.43Å; P90-I93 PolarHBondContact O-N 3.3Å; P90-I93 VanDerWaalsContact O-N 3.14Å; P90-I93 VanDerWaalsContact O-O 3.13Å; Q91-I93 PolarHBondContact O-N 3.16Å; I93-V95 HydrophobicContact CG2-CG2 4.48Å; I93-W230 HydrophobicContact CG2-CH2 4.08Å; I93-W230 HydrophobicContact CG2-CZ2 3.96Å; I93-L246 WeakPolarHBondContact CA-O 3.3Å; I93-Y247 HydrophobicContact CG1-CD2 4.4Å
94T97.9Very high97.8Very high2 Ų231 Ų311%0.01218%0.183CC..EExtended strand (participates in β ladder)trans-124.5145.5163.2-173.20000110.2T96 G245 L246 A283 Q287T94-T96 HydrophobicContact CG2-CG2 3.99Å; T94-G245 WeakPolarHBondContact O-CA 3.21Å; T94-L246 HydrophobicContact CG2-CB 3.81Å; T94-L246 HydrophobicContact CG2-CD2 4.01Å; T94-L246 HydrophobicContact CG2-CG 4.18Å; T94-L246 PolarHBondContact N-O 3.09Å; T94-L246 PolarHBondContact O-N 3.07Å; T94-A283 WeakPolarHBondContact CB-O 3.37Å; T94-A283 HydrophobicContact CG2-CB 4.48Å; T94-A283 VanDerWaalsContact CG2-O 3.29Å; T94-A283 WeakPolarHBondContact CG2-O 3.43Å; T94-Q287 VanDerWaalsContact OG1-CG 3.23Å; T94-Q287 WeakPolarHBondContact OG1-CG 3.3Å
95V97.5Very high97.8Very high0 Ų027.3 Ų27.30%016%0.159CC..EExtended strand (participates in β ladder)trans-111.7106.1179.4-176.40000107.5I78 M82 I93 T243 A244 M296 L299I78-V95 HydrophobicContact CB-CB 4.49Å; I78-V95 HydrophobicContact CB-CG2 4.12Å; I78-V95 HydrophobicContact CG2-CB 4.33Å; I78-V95 HydrophobicContact CG2-CG1 4.18Å; I78-V95 HydrophobicContact CG2-CG2 3.82Å; M82-V95 HydrophobicContact SD-CG2 3.46Å; M82-V95 WeakPolarHBondContact SD-CG2 3.41Å; I93-V95 HydrophobicContact CG2-CG2 4.48Å; V95-T243 HydrophobicContact CG1-CG2 3.47Å; V95-T243 VanDerWaalsContact CG1-CG2 3.47Å; V95-A244 CarbonylContact C-O 3.58Å; V95-A244 WeakPolarHBondContact CA-O 3.41Å; V95-M296 HydrophobicContact CB-CE 4.2Å; V95-M296 HydrophobicContact CG1-CE 4.21Å; V95-M296 WeakPolarHBondContact O-CE 3.47Å; V95-L299 HydrophobicContact CG1-CD2 4.2Å
96T96.7Very high97.8Very high15 Ų1527 Ų279%0.09216%0.158CC..  trans-160.9156.5-171.3-177.70000110.9T94 N102 T243 A244 Q287T94-T96 HydrophobicContact CG2-CG2 3.99Å; T96-N102 PolarHBondContact O-ND2 2.88Å; T96-N102 PolarHBondContact O-OD1 3.29Å; T96-T243 VanDerWaalsContact C-OG1 3.31Å; T96-T243 WeakPolarHBondContact CA-OG1 3.25Å; T96-A244 PolarHBondContact N-O 3.18Å; T96-A244 VanDerWaalsContact O-O 3.08Å; T96-Q287 HydrophobicContact CG2-CG 4.39Å
97G96Very high97.8Very high34 Ų3427 Ų2735%0.35116%0.158SC..SBendtrans57.5-156.3172.400000114.2T243 A244G97-T243 VanDerWaalsContact O-CA 3.32Å; G97-T243 WeakPolarHBondContact O-CA 3.5Å; G97-T243 PolarHBondContact O-OG1 3.44Å; G97-A244 PolarHBondContact O-N 2.91Å
98S97.3Very high97.8Very high63 Ų6325.2 Ų25.244%0.44115%0.149SC..  trans-110167.5167.769.50000110.8T100 S101 N102S98-T100 VanDerWaalsContact C-N 3.33Å; S98-T100 PolarHBondContact O-N 2.86Å; S98-S101 PolarHBondContact N-OG 3.31Å; S98-S101 PolarHBondContact O-N 3.19Å; S98-S101 PolarHBondContact O-OG 3.16Å; S98-S101 PolarHBondContact OG-N 3.3Å; S98-S101 PolarHBondContact OG-OG 3.4Å; S98-N102 PolarHBondContact O-N 2.89Å
99T97Very high97.8Very high11 Ų1124.9 Ų24.97%0.06715%0.146CC..Hα-helixtrans-52.2-52.3177.6-53.20000111S101 N102 I103 C210 V229 C231 A244T99-S101 VanDerWaalsContact C-N 3.33Å; T99-S101 PolarHBondContact O-N 3.14Å; T99-N102 CarbonylContact O-C 3.54Å; T99-N102 WeakPolarHBondContact O-CA 3.42Å; T99-N102 PolarHBondContact O-N 2.92Å; T99-I103 HydrophobicContact CG2-CD1 4.24Å; T99-I103 WeakPolarHBondContact O-CG1 3.45Å; T99-I103 PolarHBondContact O-N 2.91Å; T99-C210 VanDerWaalsContact CG2-SG 3.52Å; T99-C210 PolarHBondContact OG1-SG 3.48Å; T99-V229 HydrophobicContact CG2-CB 4.37Å; T99-V229 HydrophobicContact CG2-CG2 3.96Å; T99-C231 WeakPolarHBondContact OG1-CA 2.98Å; T99-C231 VanDerWaalsContact OG1-CB 3.32Å; T99-C231 WeakPolarHBondContact OG1-CB 3.36Å; T99-C231 PolarHBondContact OG1-N 2.83Å; T99-C231 VanDerWaalsContact OG1-N 3.1Å; T99-A244 VanDerWaalsContact N-CB 3.29Å
100T97.2Very high97.8Very high41 Ų4120.9 Ų20.925%0.25213%0.129SC..Hα-helixtrans-59.1-42.3-179.1-43.50000112.2S98 N102 I103 H104 T129 A133S98-T100 VanDerWaalsContact C-N 3.33Å; S98-T100 PolarHBondContact O-N 2.86Å; T100-N102 VanDerWaalsContact C-N 3.31Å; T100-N102 PolarHBondContact O-N 2.9Å; T100-I103 PolarHBondContact O-N 3.32Å; T100-H104 PolarHBondContact O-CD2 3.14Å; T100-H104 PolarHBondContact O-N 2.89Å; T100-T129 WeakPolarHBondContact CG2-OG1 3.45Å; T100-T129 WeakPolarHBondContact OG1-CG2 3.49Å; T100-T129 PolarHBondContact OG1-OG1 2.91Å; T100-A133 HydrophobicContact CG2-CB 4.27Å
101S97.5Very high97.8Very high40 Ų4018.5 Ų18.528%0.2811%0.114SC..Hα-helixtrans-67.1-32.8176.465.70000112.7S98 T99 H104 S105S98-S101 PolarHBondContact N-OG 3.31Å; S98-S101 PolarHBondContact O-N 3.19Å; S98-S101 PolarHBondContact O-OG 3.16Å; S98-S101 PolarHBondContact OG-N 3.3Å; S98-S101 PolarHBondContact OG-OG 3.4Å; T99-S101 VanDerWaalsContact C-N 3.33Å; T99-S101 PolarHBondContact O-N 3.14Å; S101-H104 PolarHBondContact O-N 2.98Å; S101-S105 WeakPolarHBondContact O-CB 3.24Å; S101-S105 PolarHBondContact O-N 3.11Å
102N98.2Very high97.7Very high5 Ų519.3 Ų19.33%0.02712%0.117CC..Hα-helixtrans-73.7-32.1175.9-70.7-7.4000111.6T96 S98 T99 T100 S105 A106 V229 A244 G245 L246T96-N102 PolarHBondContact O-ND2 2.88Å; T96-N102 PolarHBondContact O-OD1 3.29Å; S98-N102 PolarHBondContact O-N 2.89Å; T99-N102 CarbonylContact O-C 3.54Å; T99-N102 WeakPolarHBondContact O-CA 3.42Å; T99-N102 PolarHBondContact O-N 2.92Å; T100-N102 VanDerWaalsContact C-N 3.31Å; T100-N102 PolarHBondContact O-N 2.9Å; N102-S105 PolarHBondContact O-N 3.34Å; N102-A106 WeakPolarHBondContact O-CB 3.47Å; N102-A106 PolarHBondContact O-N 2.73Å; N102-V229 HydrophobicContact CB-CB 4.34Å; N102-V229 HydrophobicContact CB-CG1 3.81Å; N102-A244 WeakPolarHBondContact ND2-CB 3.19Å; N102-G245 PolarHBondContact ND2-O 3.18Å; N102-L246 HydrophobicContact CB-CB 4.25Å; N102-L246 HydrophobicContact CB-CD1 4.43Å
103I98.3Very high97.6Very high0 Ų020.4 Ų20.40%013%0.125CC..Hα-helixtrans-60.3-49.7168.6-64.3170.8000109.5T99 T100 S105 A106 L107 D130 A133 L177 V229T99-I103 HydrophobicContact CG2-CD1 4.24Å; T99-I103 WeakPolarHBondContact O-CG1 3.45Å; T99-I103 PolarHBondContact O-N 2.91Å; T100-I103 PolarHBondContact O-N 3.32Å; I103-S105 VanDerWaalsContact C-N 3.33Å; I103-S105 PolarHBondContact O-N 2.82Å; I103-A106 PolarHBondContact O-N 2.98Å; I103-L107 HydrophobicContact CG2-CD1 3.74Å; I103-L107 HydrophobicContact CG2-CG 4.12Å; I103-L107 WeakPolarHBondContact O-CB 3.2Å; I103-L107 VanDerWaalsContact O-CG 3.31Å; I103-L107 WeakPolarHBondContact O-CG 3.16Å; I103-L107 PolarHBondContact O-N 3.5Å; I103-D130 HydrophobicContact CD1-CB 4.12Å; I103-D130 WeakPolarHBondContact CD1-OD1 3.25Å; I103-A133 HydrophobicContact CB-CB 4.12Å; I103-A133 HydrophobicContact CG2-CB 3.59Å; I103-L177 HydrophobicContact CG2-CD2 3.71Å; I103-V229 HydrophobicContact CD1-CG2 4.32Å; I103-V229 HydrophobicContact CG1-CB 4.45Å; I103-V229 HydrophobicContact CG1-CG1 4.36Å; I103-V229 HydrophobicContact CG1-CG2 3.69Å
104H98.4Very high97.5Very high52 Ų5224 Ų2424%0.24115%0.147CC..Hα-helixtrans-58.7-42.6175.6-76.9-66.5000112.9T100 S101 A108 S136 M137 L259T100-H104 PolarHBondContact O-CD2 3.14Å; T100-H104 PolarHBondContact O-N 2.89Å; S101-H104 PolarHBondContact O-N 2.98Å; H104-A108 WeakPolarHBondContact O-CB 3.4Å; H104-A108 PolarHBondContact O-N 2.87Å; H104-S136 PolarHBondContact CE1-OG 2.94Å; H104-S136 VanDerWaalsContact CE1-OG 3.28Å; H104-M137 HydrophobicContact CB-CE 4.43Å; H104-M137 WeakPolarHBondContact O-CE 3.2Å; H104-L259 HydrophobicContact CB-CD1 4.33Å
105S97.9Very high97.4Very high1 Ų132.7 Ų32.71%0.00719%0.185CC..Hα-helixtrans-63.4-44.7178.1-171.10000112S101 N102 I103 T109S101-S105 WeakPolarHBondContact O-CB 3.24Å; S101-S105 PolarHBondContact O-N 3.11Å; N102-S105 PolarHBondContact O-N 3.34Å; I103-S105 VanDerWaalsContact C-N 3.33Å; I103-S105 PolarHBondContact O-N 2.82Å; S105-T109 WeakPolarHBondContact O-CB 3.5Å; S105-T109 PolarHBondContact O-N 3.3Å; S105-T109 PolarHBondContact O-OG1 3.47Å
106A98.3Very high97.3Very high0 Ų038.7 Ų38.70%022%0.216CC..Hα-helixtrans-63.9-49.7175.700000111.5N102 I103 A108 T109 F110 F227 L246N102-A106 WeakPolarHBondContact O-CB 3.47Å; N102-A106 PolarHBondContact O-N 2.73Å; I103-A106 PolarHBondContact O-N 2.98Å; A106-A108 PolarHBondContact O-N 3.36Å; A106-T109 WeakPolarHBondContact O-CA 3.41Å; A106-T109 WeakPolarHBondContact O-CB 3.29Å; A106-T109 PolarHBondContact O-N 3.09Å; A106-F110 HydrophobicContact CB-CD2 4.46Å; A106-F110 WeakPolarHBondContact O-CD2 3.19Å; A106-F110 PolarHBondContact O-N 2.74Å; A106-F227 HydrophobicContact CB-CD2 3.45Å; A106-F227 VanDerWaalsContact CB-CD2 3.45Å; A106-F227 HydrophobicContact CB-CE2 3.64Å; A106-F227 HydrophobicContact CB-CG 3.94Å; A106-F227 HydrophobicContact CB-CZ 4.27Å; A106-L246 HydrophobicContact CB-CD1 4.29Å
107L98.4Very high97.4Very high0 Ų041.2 Ų41.20%022%0.224CC..Hα-helixtrans-64.2-40178.9-65.4179000112I103 T109 F110 Y111 I120 V134 M137 V175I103-L107 HydrophobicContact CG2-CD1 3.74Å; I103-L107 HydrophobicContact CG2-CG 4.12Å; I103-L107 WeakPolarHBondContact O-CB 3.2Å; I103-L107 VanDerWaalsContact O-CG 3.31Å; I103-L107 WeakPolarHBondContact O-CG 3.16Å; I103-L107 PolarHBondContact O-N 3.5Å; L107-T109 PolarHBondContact O-N 2.95Å; L107-F110 PolarHBondContact O-N 3.03Å; L107-Y111 WeakPolarHBondContact O-CA 3.43Å; L107-Y111 WeakPolarHBondContact O-CB 3.37Å; L107-Y111 PolarHBondContact O-N 3Å; L107-I120 HydrophobicContact CD2-CD1 4.32Å; L107-V134 HydrophobicContact CD1-CB 4.45Å; L107-V134 HydrophobicContact CD1-CG2 3.78Å; L107-M137 HydrophobicContact CB-CB 4.46Å; L107-M137 HydrophobicContact CB-CE 4.24Å; L107-M137 HydrophobicContact CB-CG 3.94Å; L107-M137 HydrophobicContact CD1-CB 4.25Å; L107-V175 HydrophobicContact CD2-CG1 3.96Å
108A98Very high97.5Very high11 Ų1141.3 Ų41.39%0.09121%0.214CC..Hα-helixtrans-60.2-28.5174.300000112.6H104 A106 M137 L259H104-A108 WeakPolarHBondContact O-CB 3.4Å; H104-A108 PolarHBondContact O-N 2.87Å; A106-A108 PolarHBondContact O-N 3.36Å; A108-M137 HydrophobicContact CB-CE 3.98Å; A108-L259 HydrophobicContact CB-CD2 4.19Å; A108-L259 HydrophobicContact CB-CG 3.87Å
109T97.9Very high97.5Very high1 Ų140.2 Ų40.21%0.00620%0.202CC..Hα-helixtrans-84-40.2179.7-57.50000112.9S105 A106 L107 H112 K255 G258 W286S105-T109 WeakPolarHBondContact O-CB 3.5Å; S105-T109 PolarHBondContact O-N 3.3Å; S105-T109 PolarHBondContact O-OG1 3.47Å; A106-T109 WeakPolarHBondContact O-CA 3.41Å; A106-T109 WeakPolarHBondContact O-CB 3.29Å; A106-T109 PolarHBondContact O-N 3.09Å; L107-T109 PolarHBondContact O-N 2.95Å; T109-H112 PolarHBondContact O-NE2 3.17Å; T109-K255 HydrophobicContact CG2-CB 4.48Å; T109-G258 PolarHBondContact OG1-N 3.3Å; T109-W286 HydrophobicContact CG2-CZ2 3.61Å; T109-W286 VanDerWaalsContact CG2-NE1 3.35Å; T109-W286 PolarHBondContact OG1-NE1 3.33Å
110F98.3Very high97.6Very high11 Ų1139.7 Ų39.75%0.04820%0.199CC..Hα-helixtrans-104.7-26.5-170.8-69.1-68.5000114A106 L107 H112 V175 I204 F227 I248 H252 K255A106-F110 HydrophobicContact CB-CD2 4.46Å; A106-F110 WeakPolarHBondContact O-CD2 3.19Å; A106-F110 PolarHBondContact O-N 2.74Å; L107-F110 PolarHBondContact O-N 3.03Å; F110-H112 PolarHBondContact O-N 2.93Å; F110-H112 VanDerWaalsContact O-N 3.12Å; F110-V175 HydrophobicContact CB-CG2 4.49Å; F110-I204 HydrophobicContact CB-CG2 3.87Å; F110-I204 HydrophobicContact CD1-CD1 4.31Å; F110-I204 HydrophobicContact CD1-CG1 4.36Å; F110-I204 HydrophobicContact CD1-CG2 3.89Å; F110-I204 HydrophobicContact CG-CG2 3.85Å; F110-F227 HydrophobicContact CD2-CB 4.34Å; F110-F227 AromaticContact CD2-CD1 3.56Å; F110-F227 HydrophobicContact CD2-CD1 3.56Å; F110-F227 HydrophobicContact CD2-CE1 4.11Å; F110-F227 HydrophobicContact CD2-CG 4.11Å; F110-F227 HydrophobicContact CE2-CB 3.72Å; F110-F227 AromaticContact CE2-CD1 3.78Å; F110-F227 HydrophobicContact CE2-CD1 3.78Å; F110-F227 AromaticContact CE2-CG 3.99Å; F110-F227 HydrophobicContact CE2-CG 3.99Å; F110-F227 HydrophobicContact CG-CD1 4.29Å; F110-F227 HydrophobicContact CZ-CB 4.43Å; F110-I248 HydrophobicContact CE2-CD1 3.75Å; F110-I248 HydrophobicContact CZ-CD1 4.16Å; F110-I248 HydrophobicContact CZ-CG2 4.33Å; F110-H252 HydrophobicContact CE1-CB 4.01Å; F110-H252 AromaticContact CE1-CD2 3.56Å; F110-H252 AromaticContact CE1-CG 3.59Å; F110-H252 AromaticContact CE1-ND1 3.9Å; F110-H252 AromaticContact CE1-NE2 3.84Å; F110-H252 HydrophobicContact CZ-CB 4.11Å; F110-H252 AromaticContact CZ-CD2 3.8Å; F110-K255 HydrophobicContact CD1-CD 4.19Å; F110-K255 HydrophobicContact CE1-CD 3.86Å
111Y98Very high97.7Very high0 Ų037.8 Ų37.80%019%0.187CC..  trans-8590.3-179.1-174.8-124000110.9L107 P113 Y118 I120 M137 V138 K141 A174 V175L107-Y111 WeakPolarHBondContact O-CA 3.43Å; L107-Y111 WeakPolarHBondContact O-CB 3.37Å; L107-Y111 PolarHBondContact O-N 3Å; Y111-P113 VanDerWaalsContact C-CD 3.46Å; Y111-P113 HydrophobicContact CD1-CG 4.41Å; Y111-P113 HydrophobicContact CE1-CB 4.39Å; Y111-P113 HydrophobicContact CE1-CG 3.88Å; Y111-P113 HydrophobicContact CE2-CB 3.87Å; Y111-P113 HydrophobicContact CE2-CG 4.18Å; Y111-P113 VanDerWaalsContact O-CD 3.28Å; Y111-P113 WeakPolarHBondContact O-CD 3.31Å; Y111-Y118 WeakPolarHBondContact CE2-O 3.45Å; Y111-Y118 VanDerWaalsContact CZ-O 3.29Å; Y111-Y118 PolarHBondContact OH-O 3.47Å; Y111-I120 HydrophobicContact CD1-CD1 3.86Å; Y111-I120 HydrophobicContact CD2-CD1 3.74Å; Y111-I120 HydrophobicContact CD2-CG1 3.64Å; Y111-I120 HydrophobicContact CE1-CD1 3.97Å; Y111-I120 HydrophobicContact CE1-CG1 4.41Å; Y111-I120 HydrophobicContact CE2-CD1 3.87Å; Y111-I120 HydrophobicContact CE2-CG1 3.48Å; Y111-I120 VanDerWaalsContact CE2-CG1 3.48Å; Y111-I120 HydrophobicContact CG-CD1 3.74Å; Y111-I120 HydrophobicContact CG-CG1 4.18Å; Y111-M137 HydrophobicContact CD1-CG 3.98Å; Y111-V138 HydrophobicContact CE1-CG2 4.06Å; Y111-K141 HydrophobicContact CD1-CG 3.85Å; Y111-K141 HydrophobicContact CE1-CB 4.11Å; Y111-K141 HydrophobicContact CE1-CG 3.67Å; Y111-K141 WeakPolarHBondContact O-CE 3.34Å; Y111-A174 HydrophobicContact CD2-CB 4.12Å; Y111-A174 HydrophobicContact CE2-CB 4.18Å; Y111-V175 HydrophobicContact CD2-CG2 4.03Å
112H95.9Very high97.7Very high114 Ų11436 Ų3653%0.52817%0.174SC..  trans-113.276.8172.2-61-46.3000109.4T109 F110T109-H112 PolarHBondContact O-NE2 3.17Å; F110-H112 PolarHBondContact O-N 2.93Å; F110-H112 VanDerWaalsContact O-N 3.12Å
113P97.1Very high97.6Very high28 Ų2836 Ų3618%0.18217%0.174CC..  trans-61.1141.5-176.326.7-35.2000111Y111 R117 K141 Y143Y111-P113 VanDerWaalsContact C-CD 3.46Å; Y111-P113 HydrophobicContact CD1-CG 4.41Å; Y111-P113 HydrophobicContact CE1-CB 4.39Å; Y111-P113 HydrophobicContact CE1-CG 3.88Å; Y111-P113 HydrophobicContact CE2-CB 3.87Å; Y111-P113 HydrophobicContact CE2-CG 4.18Å; Y111-P113 VanDerWaalsContact O-CD 3.28Å; Y111-P113 WeakPolarHBondContact O-CD 3.31Å; P113-R117 WeakPolarHBondContact CA-O 3.34Å; P113-K141 HydrophobicContact CG-CB 4.04Å; P113-K141 HydrophobicContact CG-CD 4.49Å; P113-K141 HydrophobicContact CG-CG 4.11Å; P113-Y143 HydrophobicContact CB-CD2 4.46Å; P113-Y143 HydrophobicContact CB-CE2 3.6Å; P113-Y143 HydrophobicContact CG-CD2 4.28Å; P113-Y143 HydrophobicContact CG-CE2 3.54Å
114T96.7Very high97.3Very high75 Ų7539.7 Ų39.746%0.4619%0.194SC..  trans-116176.7173.464.70000109.3D116 R117 Y118 Y143T114-D116 PolarHBondContact O-N 3.38Å; T114-R117 PolarHBondContact N-O 3.3Å; T114-R117 PolarHBondContact OG1-N 3.32Å; T114-R117 PolarHBondContact OG1-O 2.98Å; T114-Y118 WeakPolarHBondContact O-CB 3.37Å; T114-Y143 PolarHBondContact O-OH 2.87Å
115K94.6Very high97Very high185 Ų18538.7 Ų38.780%0.80419%0.19SC*.SBendtrans-58-38.1176-172.6-178.7175.5-172.50112.7
116D96.3Very high96.5Very high125 Ų12539.7 Ų39.767%0.66820%0.195SC*.SBendtrans-99.5-23.3-172.4-53.9-46.1000112.7T114 D172T114-D116 PolarHBondContact O-N 3.38Å; D116-D172 VanDerWaalsContact O-CA 3.23Å; D116-D172 WeakPolarHBondContact O-CA 3.3Å; D116-D172 WeakPolarHBondContact O-CB 3.14Å
117R97.7Very high96.2Very high68 Ų6843.3 Ų43.326%0.25721%0.211SC..  trans-132.496.8-177.8-173.7-178.1-64.6-98.42.6110.6P113 T114 D171 D172 V173 A174 R201P113-R117 WeakPolarHBondContact CA-O 3.34Å; T114-R117 PolarHBondContact N-O 3.3Å; T114-R117 PolarHBondContact OG1-N 3.32Å; T114-R117 PolarHBondContact OG1-O 2.98Å; R117-D171 PolarHBondContact NE-O 3.29Å; R117-D171 PolarHBondContact NH1-O 2.75Å; R117-D171 PolarHBondContact NH2-O 2.64Å; R117-D172 CarbonylContact C-O 3.53Å; R117-D172 WeakPolarHBondContact CA-O 3.39Å; R117-V173 WeakPolarHBondContact CD-O 3.06Å; R117-V173 VanDerWaalsContact CG-O 3.31Å; R117-V173 WeakPolarHBondContact CG-O 3.33Å; R117-V173 PolarHBondContact NH1-O 3.12Å; R117-A174 HydrophobicContact CG-CB 3.89Å; R117-R201 PolarHBondContact NH1-O 3.22Å; R117-R201 PolarHBondContact NH2-O 2.99Å
118Y98.2Very high95.7Very high36 Ų3645.8 Ų45.814%0.14123%0.227CC..  trans-141.2-3.8-171.263-83.4000114.1Y111 T114 Y143 E147 A148 D172Y111-Y118 WeakPolarHBondContact CE2-O 3.45Å; Y111-Y118 VanDerWaalsContact CZ-O 3.29Å; Y111-Y118 PolarHBondContact OH-O 3.47Å; T114-Y118 WeakPolarHBondContact O-CB 3.37Å; Y118-Y143 AromaticContact CD2-CD1 3.72Å; Y118-Y143 HydrophobicContact CD2-CD1 3.72Å; Y118-Y143 AromaticContact CD2-CE1 3.61Å; Y118-Y143 HydrophobicContact CD2-CE1 3.61Å; Y118-Y143 HydrophobicContact CE2-CD1 4.27Å; Y118-Y143 HydrophobicContact CE2-CE1 4.33Å; Y118-Y143 HydrophobicContact CG-CD1 4.33Å; Y118-Y143 AromaticContact CG-CE1 3.76Å; Y118-Y143 HydrophobicContact CG-CE1 3.76Å; Y118-E147 HydrophobicContact CE2-CG 3.91Å; Y118-E147 WeakPolarHBondContact CE2-OE1 2.82Å; Y118-E147 PolarHBondContact OH-OE1 2.73Å; Y118-A148 HydrophobicContact CD2-CB 3.89Å; Y118-A148 HydrophobicContact CE2-CB 4.26Å; Y118-D172 PolarHBondContact N-O 2.76Å
119K98.6Very high95.5Very high41 Ų4146.9 Ų46.918%0.17823%0.233CC..EExtended strand (participates in β ladder)trans-84.8144.1-176.2-62.4-174-178.5164.20112.2E147 A148 K150 D172 V173 A174 V175K119-E147 VanDerWaalsContact CE-O 3.3Å; K119-E147 WeakPolarHBondContact CE-O 3.3Å; K119-A148 CarbonylContact C-O 3.58Å; K119-A148 WeakPolarHBondContact CA-O 3.37Å; K119-K150 HydrophobicContact CB-CB 4.46Å; K119-K150 HydrophobicContact CD-CB 4.35Å; K119-D172 HydrophobicContact CD-CB 4.42Å; K119-D172 VanDerWaalsContact CD-OD2 3.31Å; K119-D172 WeakPolarHBondContact CD-OD2 3.36Å; K119-D172 WeakPolarHBondContact CE-OD2 3.41Å; K119-D172 PolarHBondContact N-O 3.2Å; K119-D172 IonicContact NZ-OD2 3.18Å; K119-D172 PolarHBondContact NZ-OD2 2.71Å; K119-V173 HydrophobicContact CB-CG2 4.44Å; K119-A174 PolarHBondContact O-N 2.81Å; K119-V175 PolarHBondContact O-N 3.47Å
120I98.6Very high95.4Very high0 Ų046.9 Ų46.90%023%0.233CC..EExtended strand (participates in β ladder)trans-103.5124.6164.5-54.7-176.2000107.7L107 Y111 V122 V134 V138 A148 K150 V175L107-I120 HydrophobicContact CD2-CD1 4.32Å; Y111-I120 HydrophobicContact CD1-CD1 3.86Å; Y111-I120 HydrophobicContact CD2-CD1 3.74Å; Y111-I120 HydrophobicContact CD2-CG1 3.64Å; Y111-I120 HydrophobicContact CE1-CD1 3.97Å; Y111-I120 HydrophobicContact CE1-CG1 4.41Å; Y111-I120 HydrophobicContact CE2-CD1 3.87Å; Y111-I120 HydrophobicContact CE2-CG1 3.48Å; Y111-I120 VanDerWaalsContact CE2-CG1 3.48Å; Y111-I120 HydrophobicContact CG-CD1 3.74Å; Y111-I120 HydrophobicContact CG-CG1 4.18Å; I120-V122 HydrophobicContact CG2-CG1 4.21Å; I120-V134 HydrophobicContact CB-CG1 4Å; I120-V134 HydrophobicContact CD1-CG1 4.11Å; I120-V134 HydrophobicContact CG2-CG1 3.79Å; I120-V134 HydrophobicContact CG2-CG2 4.24Å; I120-V138 HydrophobicContact CD1-CG2 3.86Å; I120-V138 HydrophobicContact CG1-CG2 4.25Å; I120-A148 PolarHBondContact N-O 3.46Å; I120-K150 PolarHBondContact O-N 2.85Å; I120-V175 CarbonylContact C-O 3.47Å; I120-V175 VanDerWaalsContact CA-O 3.28Å; I120-V175 WeakPolarHBondContact CA-O 3.49Å; I120-V175 HydrophobicContact CG1-CB 4.4Å; I120-V175 HydrophobicContact CG2-CB 4.41Å
121L98.5Very high95.2Very high0 Ų049.1 Ų49.10%024%0.241CC..EExtended strand (participates in β ladder)trans-92.3127.7177-170.161.9000110.3K150 I152 V165 A168 M169 V173 V175 I176 L177L121-K150 WeakPolarHBondContact CA-O 3.44Å; L121-K150 HydrophobicContact CD1-CB 3.8Å; L121-K150 HydrophobicContact CD1-CD 3.88Å; L121-K150 HydrophobicContact CD1-CG 3.67Å; L121-K150 WeakPolarHBondContact CD1-O 3.3Å; L121-I152 HydrophobicContact CD1-CD1 3.68Å; L121-I152 HydrophobicContact CD1-CG1 3.95Å; L121-I152 HydrophobicContact CG-CD1 4.46Å; L121-I152 HydrophobicContact CG-CG1 4.37Å; L121-V165 HydrophobicContact CD2-CG1 4.35Å; L121-A168 HydrophobicContact CD1-CB 4.01Å; L121-A168 HydrophobicContact CD2-CB 4.16Å; L121-M169 HydrophobicContact CD2-CG 4.28Å; L121-V173 HydrophobicContact CB-CG1 3.83Å; L121-V175 PolarHBondContact N-O 2.55Å; L121-I176 HydrophobicContact CB-CB 4.43Å; L121-I176 HydrophobicContact CB-CG1 3.98Å; L121-I176 HydrophobicContact CB-CG2 4.36Å; L121-I176 HydrophobicContact CD2-CD1 4.1Å; L121-I176 HydrophobicContact CD2-CG1 4.24Å; L121-I176 WeakPolarHBondContact O-CA 3.5Å; L121-L177 PolarHBondContact O-N 3.22Å
122V98.1Very high95.1Very high4 Ų455.2 Ų55.22%0.02427%0.265CS..EExtended strand (participates in β ladder)trans-140.2165.6175.8-59.40000109.8I120 V134 V149 K150 V151 I152 L177I120-V122 HydrophobicContact CG2-CG1 4.21Å; V122-V134 HydrophobicContact CG1-CG1 4.23Å; V122-V134 HydrophobicContact CG1-CG2 4.05Å; V122-V149 HydrophobicContact CG2-CG1 3.84Å; V122-K150 PolarHBondContact N-O 3.49Å; V122-V151 HydrophobicContact CG2-CG2 4.18Å; V122-V151 CarbonylContact O-C 3.41Å; V122-V151 WeakPolarHBondContact O-CA 3.42Å; V122-I152 PolarHBondContact O-N 2.84Å; V122-L177 HydrophobicContact CG1-CB 4.46Å
123D95.6Very high95.2Very high5 Ų549.8 Ų49.83%0.02724%0.24CC..EExtended strand (participates in β ladder)trans-92.2166.6167.468-73.2000112.2L125 N126 I152 I160 L178 P179D123-L125 VanDerWaalsContact OD2-C 3.25Å; D123-L125 WeakPolarHBondContact OD2-CA 3.45Å; D123-L125 WeakPolarHBondContact OD2-CB 3.3Å; D123-L125 PolarHBondContact OD2-N 3.1Å; D123-N126 WeakPolarHBondContact OD1-CB 3.17Å; D123-N126 PolarHBondContact OD2-N 3.1Å; D123-I152 CarbonylContact C-O 3.47Å; D123-I152 WeakPolarHBondContact CA-O 3.5Å; D123-I160 HydrophobicContact CB-CD1 3.96Å; D123-I160 HydrophobicContact CB-CG1 3.81Å; D123-L178 HydrophobicContact CB-CD2 4.08Å; D123-P179 WeakPolarHBondContact OD1-CD 3.49Å
124D92.6Very high95.2Very high76 Ų7648.5 Ų48.541%0.40623%0.231SC..SBendtrans-92.90.9176.670.9-16.6000114.8V151 I152 R153 S154D124-V151 HydrophobicContact CB-CG1 3.66Å; D124-I152 PolarHBondContact N-O 2.93Å; D124-R153 WeakPolarHBondContact OD2-CA 3.37Å; D124-S154 PolarHBondContact OD1-N 2.67Å
125L92Very high95.2Very high32 Ų3246 Ų4617%0.16822%0.215CC..SBendtrans-103.4-4.7178.2-60-174.9000113.2D123 G157 E158 L182 Y183D123-L125 VanDerWaalsContact OD2-C 3.25Å; D123-L125 WeakPolarHBondContact OD2-CA 3.45Å; D123-L125 WeakPolarHBondContact OD2-CB 3.3Å; D123-L125 PolarHBondContact OD2-N 3.1Å; L125-G157 WeakPolarHBondContact CD2-O 3.22Å; L125-E158 VanDerWaalsContact CD1-C 3.45Å; L125-L182 HydrophobicContact CB-CD1 4.41Å; L125-L182 HydrophobicContact CB-CD2 3.89Å; L125-L182 HydrophobicContact CD1-CD1 3.99Å; L125-Y183 WeakPolarHBondContact O-CE1 3.48Å
126N88Confident95.4Very high21 Ų2138.8 Ų38.811%0.11219%0.188CC..SBendtrans-64.9162.5-176.3-153.5-6.1000111.6D123 P179D123-N126 WeakPolarHBondContact OD1-CB 3.17Å; D123-N126 PolarHBondContact OD2-N 3.1Å; N126-P179 HydrophobicContact CB-CG 4.39Å; N126-P179 WeakPolarHBondContact OD1-CB 3.33Å
127F90.7Very high95.4Very high77 Ų7733.4 Ų33.434%0.33816%0.159SC..  trans-64.2140178.4-162.1-98.9000110.5T129 D130 Y183F127-T129 HydrophobicContact CD1-CG2 3.86Å; F127-T129 HydrophobicContact CE1-CG2 4.35Å; F127-T129 PolarHBondContact O-N 2.71Å; F127-T129 VanDerWaalsContact O-N 3.07Å; F127-D130 WeakPolarHBondContact O-CB 3.32Å; F127-D130 PolarHBondContact O-N 3.29Å; F127-D130 VanDerWaalsContact O-N 3.14Å; F127-Y183 HydrophobicContact CB-CD1 4.35Å; F127-Y183 HydrophobicContact CD2-CD1 4.02Å; F127-Y183 HydrophobicContact CD2-CD2 4.19Å; F127-Y183 HydrophobicContact CD2-CE1 4.18Å; F127-Y183 HydrophobicContact CD2-CE2 4.33Å; F127-Y183 HydrophobicContact CD2-CG 4.02Å
128P89Confident95.4Very high51 Ų5130.1 Ų30.133%0.33115%0.147SC..Hα-helixtrans-56.4-33.4-171.2-3035.5000115.1D130 R131 Y132P128-D130 VanDerWaalsContact C-N 3.32Å; P128-D130 PolarHBondContact O-N 3.21Å; P128-R131 WeakPolarHBondContact O-CB 3.41Å; P128-R131 PolarHBondContact O-N 3.17Å; P128-Y132 HydrophobicContact CB-CD2 4.44Å; P128-Y132 HydrophobicContact CB-CE1 4.45Å; P128-Y132 HydrophobicContact CB-CE2 3.72Å; P128-Y132 WeakPolarHBondContact O-CD1 2.87Å; P128-Y132 VanDerWaalsContact O-CD2 3.24Å; P128-Y132 WeakPolarHBondContact O-CD2 3.44Å; P128-Y132 PolarHBondContact O-N 3.37Å
129T92.2Very high95.3Very high34 Ų3433.9 Ų33.921%0.20917%0.166CC..Hα-helixtrans-67.2-32.1-177.5-159.60000113.4T100 F127 R131 Y132 A133T100-T129 WeakPolarHBondContact CG2-OG1 3.45Å; T100-T129 WeakPolarHBondContact OG1-CG2 3.49Å; T100-T129 PolarHBondContact OG1-OG1 2.91Å; F127-T129 HydrophobicContact CD1-CG2 3.86Å; F127-T129 HydrophobicContact CE1-CG2 4.35Å; F127-T129 PolarHBondContact O-N 2.71Å; F127-T129 VanDerWaalsContact O-N 3.07Å; T129-R131 VanDerWaalsContact C-N 3.34Å; T129-Y132 PolarHBondContact O-N 2.91Å; T129-A133 WeakPolarHBondContact O-CB 3.46Å; T129-A133 PolarHBondContact O-N 3.48Å
130D96.3Very high95.2Very high2 Ų238 Ų381%0.01119%0.188CC..Hα-helixtrans-64.7-45.8176.4-62.5-116.6000109.4I103 F127 P128 A133 V134 D208I103-D130 HydrophobicContact CD1-CB 4.12Å; I103-D130 WeakPolarHBondContact CD1-OD1 3.25Å; F127-D130 WeakPolarHBondContact O-CB 3.32Å; F127-D130 PolarHBondContact O-N 3.29Å; F127-D130 VanDerWaalsContact O-N 3.14Å; P128-D130 VanDerWaalsContact C-N 3.32Å; P128-D130 PolarHBondContact O-N 3.21Å; D130-A133 PolarHBondContact O-N 2.95Å; D130-V134 WeakPolarHBondContact O-CG2 3.36Å; D130-V134 PolarHBondContact O-N 3.39Å; D130-D208 WeakPolarHBondContact OD1-CB 3.15Å
131R94.6Very high95.1Very high57 Ų5741.9 Ų41.922%0.21521%0.205CC..Hα-helixtrans-60.5-48.6175.2179.465-162.7-169.99.9111.7P128 T129 A133 V134 D135 V149P128-R131 WeakPolarHBondContact O-CB 3.41Å; P128-R131 PolarHBondContact O-N 3.17Å; T129-R131 VanDerWaalsContact C-N 3.34Å; R131-A133 VanDerWaalsContact C-N 3.29Å; R131-A133 PolarHBondContact O-N 3.33Å; R131-V134 PolarHBondContact O-N 2.97Å; R131-D135 IonicContact CZ-OD1 2.64Å; R131-D135 IonicContact CZ-OD2 2.68Å; R131-D135 IonicContact NE-OD1 2.68Å; R131-D135 PolarHBondContact NE-OD1 3.46Å; R131-D135 IonicContact NE-OD2 3.88Å; R131-D135 PolarHBondContact NE-OD2 3.48Å; R131-D135 IonicContact NH1-OD1 3.69Å; R131-D135 IonicContact NH2-OD1 3.46Å; R131-D135 PolarHBondContact NH2-OD1 3.2Å; R131-D135 IonicContact NH2-OD2 3.33Å; R131-D135 WeakPolarHBondContact O-CB 3.45Å; R131-D135 VanDerWaalsContact O-CG 3.29Å; R131-D135 PolarHBondContact O-N 3.05Å; R131-V149 VanDerWaalsContact CZ-CG1 3.44Å
132Y95.5Very high94.9Very high128 Ų12845.2 Ų45.250%0.50224%0.239SC..Hα-helixtrans-62.1-36.7179.2-57-26.1000112.4P128 T129 S136P128-Y132 HydrophobicContact CB-CD2 4.44Å; P128-Y132 HydrophobicContact CB-CE1 4.45Å; P128-Y132 HydrophobicContact CB-CE2 3.72Å; P128-Y132 WeakPolarHBondContact O-CD1 2.87Å; P128-Y132 VanDerWaalsContact O-CD2 3.24Å; P128-Y132 WeakPolarHBondContact O-CD2 3.44Å; P128-Y132 PolarHBondContact O-N 3.37Å; T129-Y132 PolarHBondContact O-N 2.91Å; Y132-S136 WeakPolarHBondContact O-CB 3.46Å; Y132-S136 PolarHBondContact O-N 2.91Å; Y132-S136 PolarHBondContact O-OG 2.85Å
133A97.5Very high94.9Very high1 Ų147.5 Ų47.51%0.00825%0.248CC..Hα-helixtrans-68.4-38.3176.700000112.4T100 I103 T129 D130 R131 S136 M137T100-A133 HydrophobicContact CG2-CB 4.27Å; I103-A133 HydrophobicContact CB-CB 4.12Å; I103-A133 HydrophobicContact CG2-CB 3.59Å; T129-A133 WeakPolarHBondContact O-CB 3.46Å; T129-A133 PolarHBondContact O-N 3.48Å; D130-A133 PolarHBondContact O-N 2.95Å; R131-A133 VanDerWaalsContact C-N 3.29Å; R131-A133 PolarHBondContact O-N 3.33Å; A133-S136 PolarHBondContact O-OG 3.29Å; A133-M137 WeakPolarHBondContact O-CB 3.32Å; A133-M137 PolarHBondContact O-N 2.65Å
134V98Very high94.9Very high0 Ų049.8 Ų49.80%026%0.264CS..Hα-helixtrans-65.6-51.4173.4167.60000111.1L107 I120 V122 D130 R131 S136 M137 V138 V149 L177L107-V134 HydrophobicContact CD1-CB 4.45Å; L107-V134 HydrophobicContact CD1-CG2 3.78Å; I120-V134 HydrophobicContact CB-CG1 4Å; I120-V134 HydrophobicContact CD1-CG1 4.11Å; I120-V134 HydrophobicContact CG2-CG1 3.79Å; I120-V134 HydrophobicContact CG2-CG2 4.24Å; V122-V134 HydrophobicContact CG1-CG1 4.23Å; V122-V134 HydrophobicContact CG1-CG2 4.05Å; D130-V134 WeakPolarHBondContact O-CG2 3.36Å; D130-V134 PolarHBondContact O-N 3.39Å; R131-V134 PolarHBondContact O-N 2.97Å; V134-S136 PolarHBondContact O-N 2.98Å; V134-M137 PolarHBondContact O-N 2.96Å; V134-V138 PolarHBondContact O-N 2.87Å; V134-V149 HydrophobicContact CG1-CG1 3.74Å; V134-V149 HydrophobicContact CG1-CG2 3.97Å; V134-L177 HydrophobicContact CG2-CD2 3.89Å
135D97.3Very high95Very high23 Ų2348 Ų4812%0.12325%0.254CS..Hα-helixtrans-57.8-50.8-177.1-73.7-15.8000111.3R131 M137 V138 E139 I145R131-D135 IonicContact CZ-OD1 2.64Å; R131-D135 IonicContact CZ-OD2 2.68Å; R131-D135 IonicContact NE-OD1 2.68Å; R131-D135 PolarHBondContact NE-OD1 3.46Å; R131-D135 IonicContact NE-OD2 3.88Å; R131-D135 PolarHBondContact NE-OD2 3.48Å; R131-D135 IonicContact NH1-OD1 3.69Å; R131-D135 IonicContact NH2-OD1 3.46Å; R131-D135 PolarHBondContact NH2-OD1 3.2Å; R131-D135 IonicContact NH2-OD2 3.33Å; R131-D135 WeakPolarHBondContact O-CB 3.45Å; R131-D135 VanDerWaalsContact O-CG 3.29Å; R131-D135 PolarHBondContact O-N 3.05Å; D135-M137 VanDerWaalsContact C-N 3.33Å; D135-M137 PolarHBondContact O-N 3.26Å; D135-V138 WeakPolarHBondContact O-CB 3.32Å; D135-V138 PolarHBondContact O-N 3.48Å; D135-E139 WeakPolarHBondContact O-CG 3.25Å; D135-E139 PolarHBondContact O-N 3.47Å; D135-I145 HydrophobicContact CB-CD1 3.84Å; D135-I145 HydrophobicContact CB-CG1 4.11Å; D135-I145 WeakPolarHBondContact OD1-CG2 3.26Å
136S97.5Very high95.1Very high34 Ų3454.2 Ų54.224%0.23828%0.282CS..Hα-helixtrans-65.9-32.5178.954.70000113.1H104 Y132 A133 V134 I140H104-S136 PolarHBondContact CE1-OG 2.94Å; H104-S136 VanDerWaalsContact CE1-OG 3.28Å; Y132-S136 WeakPolarHBondContact O-CB 3.46Å; Y132-S136 PolarHBondContact O-N 2.91Å; Y132-S136 PolarHBondContact O-OG 2.85Å; A133-S136 PolarHBondContact O-OG 3.29Å; V134-S136 PolarHBondContact O-N 2.98Å; S136-I140 WeakPolarHBondContact O-CB 3.4Å; S136-I140 WeakPolarHBondContact O-CD1 3.4Å; S136-I140 WeakPolarHBondContact O-CG1 3.29Å; S136-I140 PolarHBondContact O-N 2.67Å
137M97.3Very high95.5Very high11 Ų1157.6 Ų57.65%0.05430%0.298CS..Hα-helixtrans-67.3-39.4174.2-172.661.960.900111.7H104 L107 A108 Y111 A133 V134 D135 I140 K141H104-M137 HydrophobicContact CB-CE 4.43Å; H104-M137 WeakPolarHBondContact O-CE 3.2Å; L107-M137 HydrophobicContact CB-CB 4.46Å; L107-M137 HydrophobicContact CB-CE 4.24Å; L107-M137 HydrophobicContact CB-CG 3.94Å; L107-M137 HydrophobicContact CD1-CB 4.25Å; A108-M137 HydrophobicContact CB-CE 3.98Å; Y111-M137 HydrophobicContact CD1-CG 3.98Å; A133-M137 WeakPolarHBondContact O-CB 3.32Å; A133-M137 PolarHBondContact O-N 2.65Å; V134-M137 PolarHBondContact O-N 2.96Å; D135-M137 VanDerWaalsContact C-N 3.33Å; D135-M137 PolarHBondContact O-N 3.26Å; M137-I140 PolarHBondContact O-N 3.3Å; M137-K141 WeakPolarHBondContact O-CG 3.43Å; M137-K141 PolarHBondContact O-N 2.87Å; M137-K141 VanDerWaalsContact O-N 3.14Å
138V97Very high95.8Very high0 Ų054 Ų540%028%0.282CS..Hα-helixtrans-62-46.6175.3162.90000111.2Y111 I120 V134 D135 I140 K141 G142 Y143 A148 V149Y111-V138 HydrophobicContact CE1-CG2 4.06Å; I120-V138 HydrophobicContact CD1-CG2 3.86Å; I120-V138 HydrophobicContact CG1-CG2 4.25Å; V134-V138 PolarHBondContact O-N 2.87Å; D135-V138 WeakPolarHBondContact O-CB 3.32Å; D135-V138 PolarHBondContact O-N 3.48Å; V138-I140 PolarHBondContact O-N 3.23Å; V138-K141 PolarHBondContact O-N 2.72Å; V138-K141 VanDerWaalsContact O-N 3.1Å; V138-G142 PolarHBondContact O-N 3.35Å; V138-Y143 PolarHBondContact O-N 3.34Å; V138-A148 HydrophobicContact CG1-CB 3.47Å; V138-A148 VanDerWaalsContact CG1-CB 3.47Å; V138-A148 HydrophobicContact CG2-CB 4.24Å; V138-V149 HydrophobicContact CB-CG2 4.12Å; V138-V149 HydrophobicContact CG1-CG2 4.19Å; V138-V149 HydrophobicContact CG2-CG2 3.71Å
139E97.2Very high96.2Very high114 Ų11452 Ų5253%0.53327%0.269SS..Hα-helixtrans-62.4-41.8176.5-69.4-178.3136.800112.1D135 K141 G142 I145D135-E139 WeakPolarHBondContact O-CG 3.25Å; D135-E139 PolarHBondContact O-N 3.47Å; E139-K141 PolarHBondContact O-N 3.42Å; E139-G142 WeakPolarHBondContact O-CA 3.09Å; E139-G142 PolarHBondContact O-N 2.85Å; E139-I145 HydrophobicContact CG-CD1 4.18Å; E139-I145 HydrophobicContact CG-CG1 3.92Å
140I96.1Very high96.5Very high127 Ų12753 Ų5365%0.65127%0.27SS*.Hα-helixtrans-59.5-31.8175-74166.4000111.6S136 M137 V138 G142S136-I140 WeakPolarHBondContact O-CB 3.4Å; S136-I140 WeakPolarHBondContact O-CD1 3.4Å; S136-I140 WeakPolarHBondContact O-CG1 3.29Å; S136-I140 PolarHBondContact O-N 2.67Å; M137-I140 PolarHBondContact O-N 3.3Å; V138-I140 PolarHBondContact O-N 3.23Å; I140-G142 VanDerWaalsContact C-N 3.26Å; I140-G142 PolarHBondContact O-N 2.82Å
141K95.6Very high96.5Very high83 Ų8355.4 Ų55.436%0.36129%0.285SS..THydrogen-bonded Turntrans-81.8-0.6175.1-63.9-60.4-174.7-176.80113.6Y111 P113 M137 V138 E139 Y143Y111-K141 HydrophobicContact CD1-CG 3.85Å; Y111-K141 HydrophobicContact CE1-CB 4.11Å; Y111-K141 HydrophobicContact CE1-CG 3.67Å; Y111-K141 WeakPolarHBondContact O-CE 3.34Å; P113-K141 HydrophobicContact CG-CB 4.04Å; P113-K141 HydrophobicContact CG-CD 4.49Å; P113-K141 HydrophobicContact CG-CG 4.11Å; M137-K141 WeakPolarHBondContact O-CG 3.43Å; M137-K141 PolarHBondContact O-N 2.87Å; M137-K141 VanDerWaalsContact O-N 3.14Å; V138-K141 PolarHBondContact O-N 2.72Å; V138-K141 VanDerWaalsContact O-N 3.1Å; E139-K141 PolarHBondContact O-N 3.42Å; K141-Y143 HydrophobicContact CB-CD2 3.99Å; K141-Y143 HydrophobicContact CB-CE2 4.35Å
142G96Very high96.5Very high69 Ų6953.4 Ų53.471%0.71128%0.278SS*.THydrogen-bonded Turntrans84.315.4174.800000115V138 E139 I140V138-G142 PolarHBondContact O-N 3.35Å; E139-G142 WeakPolarHBondContact O-CA 3.09Å; E139-G142 PolarHBondContact O-N 2.85Å; I140-G142 VanDerWaalsContact C-N 3.26Å; I140-G142 PolarHBondContact O-N 2.82Å
143Y96.3Very high96.4Very high53 Ų5357 Ų5721%0.20829%0.291CS..  trans-98.9153.4173.6-67.3-93.1000110.2P113 T114 Y118 V138 K141 A148P113-Y143 HydrophobicContact CB-CD2 4.46Å; P113-Y143 HydrophobicContact CB-CE2 3.6Å; P113-Y143 HydrophobicContact CG-CD2 4.28Å; P113-Y143 HydrophobicContact CG-CE2 3.54Å; T114-Y143 PolarHBondContact O-OH 2.87Å; Y118-Y143 AromaticContact CD2-CD1 3.72Å; Y118-Y143 HydrophobicContact CD2-CD1 3.72Å; Y118-Y143 AromaticContact CD2-CE1 3.61Å; Y118-Y143 HydrophobicContact CD2-CE1 3.61Å; Y118-Y143 HydrophobicContact CE2-CD1 4.27Å; Y118-Y143 HydrophobicContact CE2-CE1 4.33Å; Y118-Y143 HydrophobicContact CG-CD1 4.33Å; Y118-Y143 AromaticContact CG-CE1 3.76Å; Y118-Y143 HydrophobicContact CG-CE1 3.76Å; V138-Y143 PolarHBondContact O-N 3.34Å; K141-Y143 HydrophobicContact CB-CD2 3.99Å; K141-Y143 HydrophobicContact CB-CE2 4.35Å; Y143-A148 HydrophobicContact CD1-CB 4.24Å; Y143-A148 HydrophobicContact CG-CB 4.02Å
144S96.1Very high96.1Very high53 Ų5357.8 Ų57.837%0.37130%0.297SS..  trans-78.7150.316868.20000110.9E146 E147 A148S144-E146 VanDerWaalsContact C-N 3.3Å; S144-E146 PolarHBondContact O-N 3.08Å; S144-E147 PolarHBondContact O-N 3.3Å; S144-E147 VanDerWaalsContact OG-CB 3.28Å; S144-E147 WeakPolarHBondContact OG-CB 3.48Å; S144-E147 PolarHBondContact OG-N 3Å; S144-A148 PolarHBondContact O-N 3.3Å
145I95.6Very high95.6Very high38 Ų3862.7 Ų62.720%0.19534%0.337CS..Hα-helixtrans-59.4-43.1-179.7-64.9169000110.7D135 E139 E147 V149D135-I145 HydrophobicContact CB-CD1 3.84Å; D135-I145 HydrophobicContact CB-CG1 4.11Å; D135-I145 WeakPolarHBondContact OD1-CG2 3.26Å; E139-I145 HydrophobicContact CG-CD1 4.18Å; E139-I145 HydrophobicContact CG-CG1 3.92Å; I145-E147 PolarHBondContact O-N 3.23Å; I145-V149 HydrophobicContact CG2-CB 4.35Å; I145-V149 HydrophobicContact CG2-CG2 4.07Å; I145-V149 WeakPolarHBondContact O-CB 3.37Å; I145-V149 PolarHBondContact O-N 3.23Å
146E94.5Very high95.1Very high163 Ų16366.2 Ų66.276%0.76236%0.356SS*.Hα-helixtrans-64.9-28.8-178.5-61.476.9-167.500113S144S144-E146 VanDerWaalsContact C-N 3.3Å; S144-E146 PolarHBondContact O-N 3.08Å
147E94.7Very high94.6Very high92 Ų9266.1 Ų66.143%0.4336%0.36SS..Hα-helixtrans-85.4-44.9-178.3-165.3-161.7152.100111.8Y118 K119 S144 I145Y118-E147 HydrophobicContact CE2-CG 3.91Å; Y118-E147 WeakPolarHBondContact CE2-OE1 2.82Å; Y118-E147 PolarHBondContact OH-OE1 2.73Å; K119-E147 VanDerWaalsContact CE-O 3.3Å; K119-E147 WeakPolarHBondContact CE-O 3.3Å; S144-E147 PolarHBondContact O-N 3.3Å; S144-E147 VanDerWaalsContact OG-CB 3.28Å; S144-E147 WeakPolarHBondContact OG-CB 3.48Å; S144-E147 PolarHBondContact OG-N 3Å; I145-E147 PolarHBondContact O-N 3.23Å
148A97.7Very high94.1Very high0 Ų067.9 Ų67.90%037%0.368CS..Hα-helixtrans-102.7-13.5-167.800000114Y118 K119 I120 V138 Y143 S144Y118-A148 HydrophobicContact CD2-CB 3.89Å; Y118-A148 HydrophobicContact CE2-CB 4.26Å; K119-A148 CarbonylContact C-O 3.58Å; K119-A148 WeakPolarHBondContact CA-O 3.37Å; I120-A148 PolarHBondContact N-O 3.46Å; V138-A148 HydrophobicContact CG1-CB 3.47Å; V138-A148 VanDerWaalsContact CG1-CB 3.47Å; V138-A148 HydrophobicContact CG2-CB 4.24Å; Y143-A148 HydrophobicContact CD1-CB 4.24Å; Y143-A148 HydrophobicContact CG-CB 4.02Å; S144-A148 PolarHBondContact O-N 3.3Å
149V97.8Very high94Very high10 Ų1070.3 Ų70.36%0.06138%0.379CS..EExtended strand (participates in β ladder)trans-104.8106.2173.9-162.60000110.5V122 R131 V134 V138 I145 V151V122-V149 HydrophobicContact CG2-CG1 3.84Å; R131-V149 VanDerWaalsContact CZ-CG1 3.44Å; V134-V149 HydrophobicContact CG1-CG1 3.74Å; V134-V149 HydrophobicContact CG1-CG2 3.97Å; V138-V149 HydrophobicContact CB-CG2 4.12Å; V138-V149 HydrophobicContact CG1-CG2 4.19Å; V138-V149 HydrophobicContact CG2-CG2 3.71Å; I145-V149 HydrophobicContact CG2-CB 4.35Å; I145-V149 HydrophobicContact CG2-CG2 4.07Å; I145-V149 WeakPolarHBondContact O-CB 3.37Å; I145-V149 PolarHBondContact O-N 3.23Å; V149-V151 HydrophobicContact CG1-CG2 4.42Å
150K97.8Very high94Very high54 Ų5465.2 Ų65.224%0.23536%0.355CS..EExtended strand (participates in β ladder)trans-87.6122.5177.8-169.9175.3-175-174.10108.8K119 I120 L121 V122 A168 T170 V173K119-K150 HydrophobicContact CB-CB 4.46Å; K119-K150 HydrophobicContact CD-CB 4.35Å; I120-K150 PolarHBondContact O-N 2.85Å; L121-K150 WeakPolarHBondContact CA-O 3.44Å; L121-K150 HydrophobicContact CD1-CB 3.8Å; L121-K150 HydrophobicContact CD1-CD 3.88Å; L121-K150 HydrophobicContact CD1-CG 3.67Å; L121-K150 WeakPolarHBondContact CD1-O 3.3Å; V122-K150 PolarHBondContact N-O 3.49Å; K150-A168 PolarHBondContact NZ-O 3.3Å; K150-T170 PolarHBondContact NZ-OG1 2.66Å; K150-V173 HydrophobicContact CD-CG2 4.24Å
151V96.6Very high94Very high54 Ų5462.8 Ų62.833%0.32734%0.343SS..EExtended strand (participates in β ladder)trans-113.5123-172.9-170.40000110.6V122 D124 V149V122-V151 HydrophobicContact CG2-CG2 4.18Å; V122-V151 CarbonylContact O-C 3.41Å; V122-V151 WeakPolarHBondContact O-CA 3.42Å; D124-V151 HydrophobicContact CB-CG1 3.66Å; V149-V151 HydrophobicContact CG1-CG2 4.42Å
152I94.6Very high94Very high15 Ų1560.7 Ų60.78%0.07734%0.335CS..EExtended strand (participates in β ladder)trans-79.8118.2168.1-50.9-54.1000107.9L121 V122 D123 D124 A164 V165 A168L121-I152 HydrophobicContact CD1-CD1 3.68Å; L121-I152 HydrophobicContact CD1-CG1 3.95Å; L121-I152 HydrophobicContact CG-CD1 4.46Å; L121-I152 HydrophobicContact CG-CG1 4.37Å; V122-I152 PolarHBondContact O-N 2.84Å; D123-I152 CarbonylContact C-O 3.47Å; D123-I152 WeakPolarHBondContact CA-O 3.5Å; D124-I152 PolarHBondContact N-O 2.93Å; I152-A164 HydrophobicContact CG2-CB 4.05Å; I152-V165 HydrophobicContact CB-CG2 4.48Å; I152-V165 HydrophobicContact CG1-CG2 4.04Å; I152-V165 HydrophobicContact CG2-CG2 4.23Å; I152-A168 HydrophobicContact CD1-CB 3.2Å; I152-A168 HydrophobicContact CG1-CB 4.5Å
153R92.7Very high94.1Very high203 Ų20361.8 Ų61.877%0.76632%0.324SS*.PPolyproline II helixtrans-88.7128.2175.8-65.5-171.1-179.9162.83110.1D124 A155D124-R153 WeakPolarHBondContact OD2-CA 3.37Å; R153-A155 PolarHBondContact O-N 3.43Å
154S91.5Very high94.1Very high18 Ų1860.6 Ų60.613%0.12633%0.326CS..PPolyproline II helixtrans-62.1132.3168.5177.20000110.5D124 D156 G157 E158 F159D124-S154 PolarHBondContact OD1-N 2.67Å; S154-D156 PolarHBondContact OG-OD1 2.91Å; S154-G157 WeakPolarHBondContact OG-CA 3.46Å; S154-G157 PolarHBondContact OG-N 3.44Å; S154-E158 PolarHBondContact OG-N 3.1Å; S154-F159 VanDerWaalsContact CB-O 3.26Å; S154-F159 WeakPolarHBondContact CB-O 3.16Å; S154-F159 PolarHBondContact OG-O 2.82Å
155A87.4Confident94.2Very high102 Ų10258 Ų5884%0.84331%0.308SS*.SBendtrans-72.3-31.718000000112.4R153R153-A155 PolarHBondContact O-N 3.43Å
156D88.3Confident94.3Very high97 Ų9757.2 Ų57.252%0.51930%0.304SS..SBendtrans-105.4-12.4179.854.425.3000113.5S154 E158 F159S154-D156 PolarHBondContact OG-OD1 2.91Å; D156-E158 VanDerWaalsContact C-N 3.29Å; D156-E158 WeakPolarHBondContact OD1-CA 3.5Å; D156-E158 PolarHBondContact OD1-N 3.37Å; D156-F159 PolarHBondContact OD1-N 3.18Å; D156-F159 WeakPolarHBondContact OD2-CD2 3.34Å
157G86.5Confident94.5Very high32 Ų3257.2 Ų57.233%0.3330%0.303SS..SBendtrans78.311.2-175.600000113.8L125 S154 R184L125-G157 WeakPolarHBondContact CD2-O 3.22Å; S154-G157 WeakPolarHBondContact OG-CA 3.46Å; S154-G157 PolarHBondContact OG-N 3.44Å; G157-R184 PolarHBondContact O-NH1 2.81Å
158E87.1Confident94.6Very high49 Ų4953.3 Ų53.323%0.22929%0.287CS..SBendtrans-124.2-37.8-174.6-58.3-165.2155.900113.1L125 S154 D156 S185 Q356L125-E158 VanDerWaalsContact CD1-C 3.45Å; S154-E158 PolarHBondContact OG-N 3.1Å; D156-E158 VanDerWaalsContact C-N 3.29Å; D156-E158 WeakPolarHBondContact OD1-CA 3.5Å; D156-E158 PolarHBondContact OD1-N 3.37Å; E158-S185 WeakPolarHBondContact O-CB 3.31Å; E158-S185 PolarHBondContact O-OG 2.99Å; E158-Q356 PolarHBondContact OE1-NE2 3.39Å
159F94.8Very high94.6Very high50 Ų5053.6 Ų53.622%0.21929%0.288CS..SBendtrans-124.5146-175.2-58.1-78.5000112.3S154 D156 Q187S154-F159 VanDerWaalsContact CB-O 3.26Å; S154-F159 WeakPolarHBondContact CB-O 3.16Å; S154-F159 PolarHBondContact OG-O 2.82Å; D156-F159 PolarHBondContact OD1-N 3.18Å; D156-F159 WeakPolarHBondContact OD2-CD2 3.34Å; F159-Q187 VanDerWaalsContact CA-OE1 3.29Å; F159-Q187 HydrophobicContact CD1-CB 3.97Å; F159-Q187 HydrophobicContact CD1-CG 4.1Å; F159-Q187 HydrophobicContact CE1-CB 4.45Å
160I96.1Very high94.7Very high7 Ų755.5 Ų55.54%0.03630%0.3CS..  trans-77.3125.6166-69.4161.3000108.1D123 V165 P179 L182 Q187 I189D123-I160 HydrophobicContact CB-CD1 3.96Å; D123-I160 HydrophobicContact CB-CG1 3.81Å; I160-V165 HydrophobicContact CG2-CG2 3.67Å; I160-P179 HydrophobicContact CD1-CG 3.92Å; I160-L182 HydrophobicContact CD1-CD1 3.98Å; I160-L182 HydrophobicContact CD1-CD2 3.62Å; I160-L182 HydrophobicContact CD1-CG 3.8Å; I160-L182 HydrophobicContact CG1-CD1 3.93Å; I160-L182 HydrophobicContact CG1-CD2 4.23Å; I160-L182 HydrophobicContact CG1-CG 4.32Å; I160-Q187 PolarHBondContact O-NE2 3.07Å; I160-I189 HydrophobicContact CB-CG2 4.47Å; I160-I189 HydrophobicContact CD1-CG2 4.28Å
161D95.9Very high94.6Very high76 Ų7658.8 Ų58.841%0.40632%0.321SS..  trans-84.5109.1169.7-178-14.2000109.9D163 A164 V165D161-D163 VanDerWaalsContact C-N 3.31Å; D161-D163 PolarHBondContact O-N 3.18Å; D161-D163 WeakPolarHBondContact OD1-CB 3.38Å; D161-D163 PolarHBondContact OD1-N 3.47Å; D161-A164 HydrophobicContact CB-CB 3.87Å; D161-A164 PolarHBondContact O-N 2.64Å; D161-A164 PolarHBondContact OD1-N 3.22Å; D161-V165 WeakPolarHBondContact O-CG2 3.17Å; D161-V165 PolarHBondContact O-N 3.13Å
162E96.6Very high94.7Very high40 Ų4058 Ų5819%0.18731%0.314CS..Hα-helixtrans-66.3-30.8-178.6-58.7177.5139.200113.1V165 I166 I189 D190 R193 L194E162-V165 PolarHBondContact O-N 3Å; E162-I166 WeakPolarHBondContact O-CD1 3.5Å; E162-I166 VanDerWaalsContact O-CG1 3.29Å; E162-I166 WeakPolarHBondContact O-CG1 3.44Å; E162-I166 PolarHBondContact O-N 3.04Å; E162-I189 WeakPolarHBondContact OE1-CA 3.26Å; E162-D190 WeakPolarHBondContact OE1-CB 3.43Å; E162-D190 PolarHBondContact OE1-N 2.86Å; E162-R193 IonicContact OE2-NH1 2.97Å; E162-L194 HydrophobicContact CB-CD2 4.44Å
163D97.3Very high94.9Very high91 Ų9157.2 Ų57.249%0.48731%0.31SS..Hα-helixtrans-69.3-41176.8-69.2-15.3000109.8D161 V165 I166 E167 R193D161-D163 VanDerWaalsContact C-N 3.31Å; D161-D163 PolarHBondContact O-N 3.18Å; D161-D163 WeakPolarHBondContact OD1-CB 3.38Å; D161-D163 PolarHBondContact OD1-N 3.47Å; D163-V165 VanDerWaalsContact C-N 3.34Å; D163-V165 PolarHBondContact O-N 3.47Å; D163-I166 PolarHBondContact O-N 2.97Å; D163-E167 WeakPolarHBondContact O-CB 3.29Å; D163-E167 PolarHBondContact O-N 2.52Å; D163-R193 IonicContact OD1-CZ 3.86Å; D163-R193 IonicContact OD1-NH1 2.7Å; D163-R193 PolarHBondContact OD1-NH1 2.95Å; D163-R193 IonicContact OD1-NH2 3.98Å; D163-R193 PolarHBondContact OD1-NH2 2.79Å
164A96.9Very high95.2Very high28 Ų2848.1 Ų48.123%0.23128%0.278CS..Hα-helixtrans-64.2-37.3173.300000112.4I152 D161 A168I152-A164 HydrophobicContact CG2-CB 4.05Å; D161-A164 HydrophobicContact CB-CB 3.87Å; D161-A164 PolarHBondContact O-N 2.64Å; D161-A164 PolarHBondContact OD1-N 3.22Å; A164-A168 VanDerWaalsContact O-CB 3.32Å; A164-A168 WeakPolarHBondContact O-CB 3.43Å; A164-A168 PolarHBondContact O-N 3.27Å; A164-A168 VanDerWaalsContact O-N 3.09Å
165V97.8Very high95.5Very high0 Ų047.2 Ų47.20%027%0.272CS..Hα-helixtrans-60.2-47.7172.11750000110.4L121 I152 I160 D161 E162 D163 A168 M169 L178 L194L121-V165 HydrophobicContact CD2-CG1 4.35Å; I152-V165 HydrophobicContact CB-CG2 4.48Å; I152-V165 HydrophobicContact CG1-CG2 4.04Å; I152-V165 HydrophobicContact CG2-CG2 4.23Å; I160-V165 HydrophobicContact CG2-CG2 3.67Å; D161-V165 WeakPolarHBondContact O-CG2 3.17Å; D161-V165 PolarHBondContact O-N 3.13Å; E162-V165 PolarHBondContact O-N 3Å; D163-V165 VanDerWaalsContact C-N 3.34Å; D163-V165 PolarHBondContact O-N 3.47Å; V165-A168 PolarHBondContact O-N 3.39Å; V165-M169 HydrophobicContact CG1-CE 3.94Å; V165-M169 WeakPolarHBondContact O-CG 3.3Å; V165-M169 PolarHBondContact O-N 3.38Å; V165-L178 HydrophobicContact CG1-CD1 3.78Å; V165-L194 HydrophobicContact CB-CD2 4.13Å; V165-L194 HydrophobicContact CG1-CD2 3.77Å
166I98.2Very high96Very high21 Ų2142.4 Ų42.411%0.10823%0.232CC..Hα-helixtrans-64.8-43.5-179.9-67.8162.6000111.5E162 D163 A168 M169 R193 L194 E197E162-I166 WeakPolarHBondContact O-CD1 3.5Å; E162-I166 VanDerWaalsContact O-CG1 3.29Å; E162-I166 WeakPolarHBondContact O-CG1 3.44Å; E162-I166 PolarHBondContact O-N 3.04Å; D163-I166 PolarHBondContact O-N 2.97Å; I166-A168 PolarHBondContact O-N 3.31Å; I166-M169 HydrophobicContact CG1-CE 4.22Å; I166-M169 WeakPolarHBondContact O-CB 3.41Å; I166-M169 PolarHBondContact O-N 3.28Å; I166-M169 VanDerWaalsContact O-N 3.08Å; I166-R193 HydrophobicContact CD1-CG 4.22Å; I166-L194 HydrophobicContact CD1-CD2 4.29Å; I166-L194 HydrophobicContact CG1-CD2 3.87Å; I166-E197 HydrophobicContact CD1-CG 4.04Å; I166-E197 HydrophobicContact CG1-CB 4.21Å; I166-E197 HydrophobicContact CG1-CG 4.08Å; I166-E197 HydrophobicContact CG2-CB 4.33Å; I166-E197 HydrophobicContact CG2-CG 4.08Å
167E97.6Very high96.5Very high162 Ų16237.8 Ų37.876%0.75721%0.208SC*.Hα-helixtrans-58.9-35.9176.3-176.2177.9178.700111.5D163 M169D163-E167 WeakPolarHBondContact O-CB 3.29Å; D163-E167 PolarHBondContact O-N 2.52Å; E167-M169 VanDerWaalsContact C-N 3.3Å; E167-M169 PolarHBondContact O-N 3.1Å
168A97.9Very high97.1Very high10 Ų1036.3 Ų36.38%0.08319%0.192CC..THydrogen-bonded Turntrans-80.5-4179.100000114.8L121 K150 I152 A164 V165 I166 T170L121-A168 HydrophobicContact CD1-CB 4.01Å; L121-A168 HydrophobicContact CD2-CB 4.16Å; K150-A168 PolarHBondContact NZ-O 3.3Å; I152-A168 HydrophobicContact CD1-CB 3.2Å; I152-A168 HydrophobicContact CG1-CB 4.5Å; A164-A168 VanDerWaalsContact O-CB 3.32Å; A164-A168 WeakPolarHBondContact O-CB 3.43Å; A164-A168 PolarHBondContact O-N 3.27Å; A164-A168 VanDerWaalsContact O-N 3.09Å; V165-A168 PolarHBondContact O-N 3.39Å; I166-A168 PolarHBondContact O-N 3.31Å; A168-T170 PolarHBondContact O-N 3.29Å; A168-T170 PolarHBondContact O-OG1 3.12Å
169M98.3Very high97.6Very high6 Ų634.2 Ų34.23%0.0318%0.183CC..  trans-72.969.1170.7-61.2-172.3-17100110.4L121 V165 I166 E167 I176 L194 E197 A198 R201 I203L121-M169 HydrophobicContact CD2-CG 4.28Å; V165-M169 HydrophobicContact CG1-CE 3.94Å; V165-M169 WeakPolarHBondContact O-CG 3.3Å; V165-M169 PolarHBondContact O-N 3.38Å; I166-M169 HydrophobicContact CG1-CE 4.22Å; I166-M169 WeakPolarHBondContact O-CB 3.41Å; I166-M169 PolarHBondContact O-N 3.28Å; I166-M169 VanDerWaalsContact O-N 3.08Å; E167-M169 VanDerWaalsContact C-N 3.3Å; E167-M169 PolarHBondContact O-N 3.1Å; M169-I176 HydrophobicContact CE-CD1 3.71Å; M169-I176 HydrophobicContact CG-CD1 3.78Å; M169-I176 HydrophobicContact SD-CD1 3.88Å; M169-L194 HydrophobicContact CE-CB 4.44Å; M169-L194 HydrophobicContact CE-CD2 3.99Å; M169-E197 HydrophobicContact CE-CB 4.35Å; M169-E197 HydrophobicContact SD-CB 3.9Å; M169-A198 HydrophobicContact CE-CB 4.39Å; M169-A198 HydrophobicContact SD-CB 4.05Å; M169-R201 WeakPolarHBondContact O-CD 3.3Å; M169-R201 PolarHBondContact O-NE 2.86Å; M169-I203 HydrophobicContact CB-CD1 3.72Å; M169-I203 HydrophobicContact CG-CD1 4.3Å
170T97.9Very high97.8Very high51 Ų5131.8 Ų31.831%0.31317%0.172SC..  trans-85.3163.7178.243.80000111.3K150 A168 D172 V173K150-T170 PolarHBondContact NZ-OG1 2.66Å; A168-T170 PolarHBondContact O-N 3.29Å; A168-T170 PolarHBondContact O-OG1 3.12Å; T170-D172 VanDerWaalsContact CB-OD1 3.29Å; T170-D172 WeakPolarHBondContact CB-OD1 3.12Å; T170-D172 PolarHBondContact O-N 2.85Å; T170-D172 PolarHBondContact OG1-OD1 3.02Å; T170-V173 WeakPolarHBondContact O-CB 3.48Å; T170-V173 PolarHBondContact O-N 2.81Å
171D97.3Very high97.8Very high123 Ų12331.6 Ų31.666%0.65817%0.171SC*.THydrogen-bonded Turntrans-60-19.4-175.8-70-26.5000114.2R117R117-D171 PolarHBondContact NE-O 3.29Å; R117-D171 PolarHBondContact NH1-O 2.75Å; R117-D171 PolarHBondContact NH2-O 2.64Å
172D98.1Very high97.8Very high36 Ų3628.1 Ų28.119%0.19315%0.153CC..THydrogen-bonded Turntrans-82.7-8.1177.662.2-5.1000114.5D116 R117 Y118 K119 T170D116-D172 VanDerWaalsContact O-CA 3.23Å; D116-D172 WeakPolarHBondContact O-CA 3.3Å; D116-D172 WeakPolarHBondContact O-CB 3.14Å; R117-D172 CarbonylContact C-O 3.53Å; R117-D172 WeakPolarHBondContact CA-O 3.39Å; Y118-D172 PolarHBondContact N-O 2.76Å; K119-D172 HydrophobicContact CD-CB 4.42Å; K119-D172 VanDerWaalsContact CD-OD2 3.31Å; K119-D172 WeakPolarHBondContact CD-OD2 3.36Å; K119-D172 WeakPolarHBondContact CE-OD2 3.41Å; K119-D172 PolarHBondContact N-O 3.2Å; K119-D172 IonicContact NZ-OD2 3.18Å; K119-D172 PolarHBondContact NZ-OD2 2.71Å; T170-D172 VanDerWaalsContact CB-OD1 3.29Å; T170-D172 WeakPolarHBondContact CB-OD1 3.12Å; T170-D172 PolarHBondContact O-N 2.85Å; T170-D172 PolarHBondContact OG1-OD1 3.02Å
173V98.6Very high97.7Very high0 Ų028.4 Ų28.40%015%0.152CC..EExtended strand (participates in β ladder)trans-81.6121.7178-178.70000110.4R117 K119 L121 K150 T170 I176 I203R117-V173 WeakPolarHBondContact CD-O 3.06Å; R117-V173 VanDerWaalsContact CG-O 3.31Å; R117-V173 WeakPolarHBondContact CG-O 3.33Å; R117-V173 PolarHBondContact NH1-O 3.12Å; K119-V173 HydrophobicContact CB-CG2 4.44Å; L121-V173 HydrophobicContact CB-CG1 3.83Å; K150-V173 HydrophobicContact CD-CG2 4.24Å; T170-V173 WeakPolarHBondContact O-CB 3.48Å; T170-V173 PolarHBondContact O-N 2.81Å; V173-I176 HydrophobicContact CG1-CG1 4.01Å; V173-I203 HydrophobicContact CB-CD1 4.12Å; V173-I203 HydrophobicContact CG1-CD1 4.33Å; V173-I203 HydrophobicContact CG1-CG2 3.82Å
174A98.5Very high97.4Very high11 Ų1126 Ų269%0.09114%0.136CC..EExtended strand (participates in β ladder)trans-90.7-45.4177.100000112.3Y111 R117 K119 I204Y111-A174 HydrophobicContact CD2-CB 4.12Å; Y111-A174 HydrophobicContact CE2-CB 4.18Å; R117-A174 HydrophobicContact CG-CB 3.89Å; K119-A174 PolarHBondContact O-N 2.81Å; A174-I204 PolarHBondContact O-N 2.89Å; A174-I204 VanDerWaalsContact O-N 3.16Å
175V98.7Very high97.3Very high0 Ų024.7 Ų24.70%013%0.126CC..EExtended strand (participates in β ladder)trans-137.4144.1-173-176.70000109.9L107 F110 Y111 K119 I120 L121 I204 F227L107-V175 HydrophobicContact CD2-CG1 3.96Å; F110-V175 HydrophobicContact CB-CG2 4.49Å; Y111-V175 HydrophobicContact CD2-CG2 4.03Å; K119-V175 PolarHBondContact O-N 3.47Å; I120-V175 CarbonylContact C-O 3.47Å; I120-V175 VanDerWaalsContact CA-O 3.28Å; I120-V175 WeakPolarHBondContact CA-O 3.49Å; I120-V175 HydrophobicContact CG1-CB 4.4Å; I120-V175 HydrophobicContact CG2-CB 4.41Å; L121-V175 PolarHBondContact N-O 2.55Å; V175-I204 CarbonylContact C-O 3.5Å; V175-I204 WeakPolarHBondContact CA-O 3.44Å; V175-I204 HydrophobicContact CG2-CB 4.27Å; V175-F227 HydrophobicContact CG1-CE1 4.14Å; V175-F227 HydrophobicContact CG1-CZ 4.33Å
176I98.7Very high97.2Very high0 Ų024.7 Ų24.70%013%0.126CC..EExtended strand (participates in β ladder)trans-117.6133.4170.3-52.3-178.6000108L121 M169 V173 L178 A198 I203 I204 I205 G206L121-I176 HydrophobicContact CB-CB 4.43Å; L121-I176 HydrophobicContact CB-CG1 3.98Å; L121-I176 HydrophobicContact CB-CG2 4.36Å; L121-I176 HydrophobicContact CD2-CD1 4.1Å; L121-I176 HydrophobicContact CD2-CG1 4.24Å; L121-I176 WeakPolarHBondContact O-CA 3.5Å; M169-I176 HydrophobicContact CE-CD1 3.71Å; M169-I176 HydrophobicContact CG-CD1 3.78Å; M169-I176 HydrophobicContact SD-CD1 3.88Å; V173-I176 HydrophobicContact CG1-CG1 4.01Å; I176-L178 HydrophobicContact CG2-CD1 3.65Å; I176-L178 HydrophobicContact CG2-CG 3.75Å; I176-A198 HydrophobicContact CD1-CB 4Å; I176-I203 HydrophobicContact CD1-CG2 3.87Å; I176-I203 HydrophobicContact CG1-CG2 3.6Å; I176-I204 PolarHBondContact N-O 2.95Å; I176-I205 HydrophobicContact CB-CB 4.27Å; I176-I205 HydrophobicContact CB-CD1 4.28Å; I176-I205 HydrophobicContact CB-CG1 3.98Å; I176-I205 HydrophobicContact CD1-CD1 4.37Å; I176-I205 HydrophobicContact CG2-CD1 4.17Å; I176-I205 HydrophobicContact CG2-CG1 4.2Å; I176-G206 PolarHBondContact O-N 2.88Å
177L98.6Very high97.2Very high1 Ų124.8 Ų24.81%0.00513%0.126CC..EExtended strand (participates in β ladder)trans-130.3115.4171.2178.763.1000109.4I103 L121 V122 V134 G206 F227I103-L177 HydrophobicContact CG2-CD2 3.71Å; L121-L177 PolarHBondContact O-N 3.22Å; V122-L177 HydrophobicContact CG1-CB 4.46Å; V134-L177 HydrophobicContact CG2-CD2 3.89Å; L177-G206 WeakPolarHBondContact CA-O 3.22Å; L177-F227 HydrophobicContact CD1-CE2 4.01Å; L177-F227 HydrophobicContact CD1-CZ 4.25Å
178L98.3Very high97.2Very high1 Ų118.3 Ų18.31%0.00510%0.096CC..EExtended strand (participates in β ladder)trans-131.4150.6-177.3-66.7167.7000111.2D123 V165 I176 I189 L194 G206 F207 D208D123-L178 HydrophobicContact CB-CD2 4.08Å; V165-L178 HydrophobicContact CG1-CD1 3.78Å; I176-L178 HydrophobicContact CG2-CD1 3.65Å; I176-L178 HydrophobicContact CG2-CG 3.75Å; L178-I189 HydrophobicContact CB-CD1 3.85Å; L178-I189 HydrophobicContact CD1-CD1 4.44Å; L178-L194 HydrophobicContact CD1-CD1 4.02Å; L178-G206 PolarHBondContact N-O 3.32Å; L178-F207 HydrophobicContact CB-CD1 4.2Å; L178-F207 HydrophobicContact CB-CE1 4.3Å; L178-F207 CarbonylContact O-C 3.57Å; L178-F207 WeakPolarHBondContact O-CA 3.34Å; L178-D208 PolarHBondContact O-N 2.97Å
179P97.8Very high97.2Very high4 Ų418 Ų183%0.0269%0.093CC..EExtended strand (participates in β ladder)trans-75.9135.1171.630.2-30.1000110.2D123 N126 I160 L182 I189D123-P179 WeakPolarHBondContact OD1-CD 3.49Å; N126-P179 HydrophobicContact CB-CG 4.39Å; N126-P179 WeakPolarHBondContact OD1-CB 3.33Å; I160-P179 HydrophobicContact CD1-CG 3.92Å; P179-L182 HydrophobicContact CG-CD2 3.62Å; P179-L182 HydrophobicContact CG-CG 4.41Å; P179-I189 WeakPolarHBondContact O-CD1 3.45Å; P179-I189 VanDerWaalsContact O-CG1 3.32Å; P179-I189 WeakPolarHBondContact O-CG1 3.35Å
180T97.9Very high97.1Very high0 Ų021.3 Ų21.30%011%0.11CC..SBendtrans-69.6-37.7174-64.20000112.4I188 I189 M191 F207 D208 L209 A212 I216T180-I188 WeakPolarHBondContact O-CA 3.09Å; T180-I189 PolarHBondContact O-N 3.23Å; T180-I189 VanDerWaalsContact O-N 3.1Å; T180-M191 HydrophobicContact CG2-CE 3.37Å; T180-M191 HydrophobicContact CG2-CG 4.04Å; T180-M191 HydrophobicContact CG2-SD 3.44Å; T180-M191 WeakPolarHBondContact CG2-SD 3.49Å; T180-M191 PolarHBondContact OG1-SD 3.04Å; T180-F207 WeakPolarHBondContact OG1-CB 3.46Å; T180-D208 PolarHBondContact N-O 3.31Å; T180-L209 HydrophobicContact CG2-CD2 4.43Å; T180-L209 WeakPolarHBondContact OG1-CD2 3.03Å; T180-A212 HydrophobicContact CG2-CB 3.56Å; T180-I216 HydrophobicContact CG2-CD1 3.97Å
181V97.7Very high97.2Very high3 Ų319.4 Ų19.42%0.01810%0.098CC..BIsolated β-bridgetrans-126.1119.1172.81740000108.3Y183 Q187 I188 H211 A212 I216V181-Y183 PolarHBondContact O-N 3.11Å; V181-Q187 CarbonylContact C-O 3.59Å; V181-Q187 WeakPolarHBondContact CA-O 3.28Å; V181-I188 HydrophobicContact CG2-CG1 3.94Å; V181-H211 HydrophobicContact CB-CB 3.83Å; V181-H211 HydrophobicContact CG1-CB 3.82Å; V181-A212 HydrophobicContact CB-CB 4.28Å; V181-A212 HydrophobicContact CG2-CB 3.71Å; V181-I216 HydrophobicContact CG2-CD1 4.01Å
182L95.8Very high97.2Very high3 Ų317 Ų172%0.0168%0.082CC..  trans-61.6127.6174.1-83.4-179.4000110.3L125 I160 P179 R184 S185 A186 Q187L125-L182 HydrophobicContact CB-CD1 4.41Å; L125-L182 HydrophobicContact CB-CD2 3.89Å; L125-L182 HydrophobicContact CD1-CD1 3.99Å; I160-L182 HydrophobicContact CD1-CD1 3.98Å; I160-L182 HydrophobicContact CD1-CD2 3.62Å; I160-L182 HydrophobicContact CD1-CG 3.8Å; I160-L182 HydrophobicContact CG1-CD1 3.93Å; I160-L182 HydrophobicContact CG1-CD2 4.23Å; I160-L182 HydrophobicContact CG1-CG 4.32Å; P179-L182 HydrophobicContact CG-CD2 3.62Å; P179-L182 HydrophobicContact CG-CG 4.41Å; L182-R184 VanDerWaalsContact C-N 3.26Å; L182-R184 PolarHBondContact O-N 3.35Å; L182-S185 WeakPolarHBondContact CD1-OG 3.21Å; L182-A186 WeakPolarHBondContact O-CA 3.34Å; L182-A186 PolarHBondContact O-N 3.12Å; L182-Q187 HydrophobicContact CB-CB 4.16Å; L182-Q187 HydrophobicContact CD1-CB 4Å; L182-Q187 VanDerWaalsContact CD1-OE1 3.23Å; L182-Q187 HydrophobicContact CG-CB 4.33Å; L182-Q187 PolarHBondContact N-O 3.07Å
183Y93Very high97.2Very high46 Ų4619.5 Ų19.518%0.189%0.089CC..THydrogen-bonded Turntrans-65.2-32.1-177.981.4-82.9000112.1L125 F127 V181 H211 H352 R377 R383L125-Y183 WeakPolarHBondContact O-CE1 3.48Å; F127-Y183 HydrophobicContact CB-CD1 4.35Å; F127-Y183 HydrophobicContact CD2-CD1 4.02Å; F127-Y183 HydrophobicContact CD2-CD2 4.19Å; F127-Y183 HydrophobicContact CD2-CE1 4.18Å; F127-Y183 HydrophobicContact CD2-CE2 4.33Å; F127-Y183 HydrophobicContact CD2-CG 4.02Å; V181-Y183 PolarHBondContact O-N 3.11Å; Y183-H211 WeakPolarHBondContact CB-CD2 3.41Å; Y183-H211 VanDerWaalsContact CB-NE2 3.32Å; Y183-H211 WeakPolarHBondContact CB-NE2 3.22Å; Y183-H352 PolarHBondContact O-NE2 3.44Å; Y183-R377 HydrophobicContact CE2-CG 4.26Å; Y183-R383 WeakPolarHBondContact O-CD 3.28Å; Y183-R383 PolarHBondContact O-NH1 3.08Å
184R91.8Very high97.2Very high40 Ų4019.5 Ų19.515%0.1519%0.089CC..THydrogen-bonded Turntrans-85.3-44.4-174.6-175.9174.8174.7-95.4-11.1113.5G157 L182 C354 E378G157-R184 PolarHBondContact O-NH1 2.81Å; L182-R184 VanDerWaalsContact C-N 3.26Å; L182-R184 PolarHBondContact O-N 3.35Å; R184-C354 PolarHBondContact O-SG 2.85Å; R184-E378 PolarHBondContact NE-O 2.8Å; R184-E378 VanDerWaalsContact NE-O 3.14Å
185S94.2Very high97.2Very high1 Ų119 Ų191%0.0079%0.085CC..THydrogen-bonded Turntrans-106.81.8-174.656.40000113.9E158 L182 Q187 G341 N342E158-S185 WeakPolarHBondContact O-CB 3.31Å; E158-S185 PolarHBondContact O-OG 2.99Å; L182-S185 WeakPolarHBondContact CD1-OG 3.21Å; S185-Q187 PolarHBondContact O-N 2.85Å; S185-G341 WeakPolarHBondContact CA-O 3.01Å; S185-G341 WeakPolarHBondContact CB-O 3.29Å; S185-N342 WeakPolarHBondContact O-CA 3.5Å; S185-N342 WeakPolarHBondContact O-CB 3.28Å
186A96.4Very high97.2Very high0 Ų023.4 Ų23.40%011%0.105CC..  trans55.614.1-173.700000114.5L182 I188 R349 G350L182-A186 WeakPolarHBondContact O-CA 3.34Å; L182-A186 PolarHBondContact O-N 3.12Å; A186-I188 PolarHBondContact O-N 2.83Å; A186-R349 HydrophobicContact CB-CG 4.18Å; A186-R349 CarbonylContact O-C 3.26Å; A186-R349 WeakPolarHBondContact O-CA 3.36Å; A186-G350 PolarHBondContact O-N 3.24Å
187Q97.6Very high97.2Very high23 Ų2325.2 Ų25.211%0.10711%0.114CC..BIsolated β-bridgetrans-59.3127.8179.8-174.9-173.24.500110.5F159 I160 V181 L182 S185 V348F159-Q187 VanDerWaalsContact CA-OE1 3.29Å; F159-Q187 HydrophobicContact CD1-CB 3.97Å; F159-Q187 HydrophobicContact CD1-CG 4.1Å; F159-Q187 HydrophobicContact CE1-CB 4.45Å; I160-Q187 PolarHBondContact O-NE2 3.07Å; V181-Q187 CarbonylContact C-O 3.59Å; V181-Q187 WeakPolarHBondContact CA-O 3.28Å; L182-Q187 HydrophobicContact CB-CB 4.16Å; L182-Q187 HydrophobicContact CD1-CB 4Å; L182-Q187 VanDerWaalsContact CD1-OE1 3.23Å; L182-Q187 HydrophobicContact CG-CB 4.33Å; L182-Q187 PolarHBondContact N-O 3.07Å; S185-Q187 PolarHBondContact O-N 2.85Å; Q187-V348 CarbonylContact C-O 3.26Å; Q187-V348 WeakPolarHBondContact CA-O 3.32Å
188I98Very high97.2Very high26 Ų2625.2 Ų25.213%0.13311%0.113CC..BIsolated β-bridgetrans-88.4124.6166.4-56.3167.5000107.6T180 V181 A186 I216 V348 R349T180-I188 WeakPolarHBondContact O-CA 3.09Å; V181-I188 HydrophobicContact CG2-CG1 3.94Å; A186-I188 PolarHBondContact O-N 2.83Å; I188-I216 HydrophobicContact CD1-CD1 4.41Å; I188-I216 HydrophobicContact CD1-CG2 3.86Å; I188-I216 HydrophobicContact CG1-CD1 4.36Å; I188-I216 HydrophobicContact CG1-CG2 4.37Å; I188-I216 HydrophobicContact CG2-CD1 3.96Å; I188-V348 PolarHBondContact N-O 2.9Å; I188-R349 VanDerWaalsContact CD1-C 3.44Å; I188-R349 VanDerWaalsContact CD1-O 3.25Å; I188-R349 WeakPolarHBondContact CD1-O 3.3Å
189I97.3Very high97.2Very high3 Ų328.2 Ų28.22%0.01513%0.127CC..PPolyproline II helixtrans-87.3147.9170.363.1170000111.1I160 E162 L178 P179 T180 M191 L194 F207I160-I189 HydrophobicContact CB-CG2 4.47Å; I160-I189 HydrophobicContact CD1-CG2 4.28Å; E162-I189 WeakPolarHBondContact OE1-CA 3.26Å; L178-I189 HydrophobicContact CB-CD1 3.85Å; L178-I189 HydrophobicContact CD1-CD1 4.44Å; P179-I189 WeakPolarHBondContact O-CD1 3.45Å; P179-I189 VanDerWaalsContact O-CG1 3.32Å; P179-I189 WeakPolarHBondContact O-CG1 3.35Å; T180-I189 PolarHBondContact O-N 3.23Å; T180-I189 VanDerWaalsContact O-N 3.1Å; I189-M191 VanDerWaalsContact C-N 3.29Å; I189-M191 HydrophobicContact CG1-CG 4.38Å; I189-M191 PolarHBondContact O-N 2.95Å; I189-L194 HydrophobicContact CB-CD1 4.24Å; I189-L194 HydrophobicContact CD1-CD1 3.84Å; I189-L194 HydrophobicContact CG1-CD1 4.39Å; I189-F207 HydrophobicContact CD1-CD1 3.93Å; I189-F207 HydrophobicContact CD1-CE1 3.71Å
190D97.7Very high97.3Very high75 Ų7534.6 Ų34.640%0.40116%0.155SC..  trans-7480173.6-170.2-17.7000110.1E162 K192 R193 L194E162-D190 WeakPolarHBondContact OE1-CB 3.43Å; E162-D190 PolarHBondContact OE1-N 2.86Å; D190-K192 PolarHBondContact O-N 3.29Å; D190-K192 VanDerWaalsContact O-N 3.17Å; D190-K192 PolarHBondContact OD1-N 3.32Å; D190-R193 HydrophobicContact CB-CB 3.97Å; D190-R193 PolarHBondContact O-N 2.84Å; D190-R193 PolarHBondContact OD1-N 2.72Å; D190-R193 WeakPolarHBondContact OD2-CB 3.43Å; D190-L194 WeakPolarHBondContact O-CG 3.29Å; D190-L194 PolarHBondContact O-N 3.06Å
191M98.2Very high97.3Very high12 Ų1238.5 Ų38.56%0.05917%0.169CC..Hα-helixtrans-53.9-35177.7-67.5-175.3-79.200112.5T180 I189 T195 F207 L209 I218 F220 I223T180-M191 HydrophobicContact CG2-CE 3.37Å; T180-M191 HydrophobicContact CG2-CG 4.04Å; T180-M191 HydrophobicContact CG2-SD 3.44Å; T180-M191 WeakPolarHBondContact CG2-SD 3.49Å; T180-M191 PolarHBondContact OG1-SD 3.04Å; I189-M191 VanDerWaalsContact C-N 3.29Å; I189-M191 HydrophobicContact CG1-CG 4.38Å; I189-M191 PolarHBondContact O-N 2.95Å; M191-T195 WeakPolarHBondContact O-CB 3.46Å; M191-T195 PolarHBondContact O-N 3.39Å; M191-T195 PolarHBondContact O-OG1 2.81Å; M191-F207 HydrophobicContact CB-CE1 4.2Å; M191-F207 HydrophobicContact CB-CE2 4.06Å; M191-F207 HydrophobicContact CB-CZ 3.84Å; M191-F207 HydrophobicContact CG-CD1 3.92Å; M191-F207 HydrophobicContact CG-CD2 4.3Å; M191-F207 HydrophobicContact CG-CE1 3.79Å; M191-F207 HydrophobicContact CG-CE2 4.18Å; M191-F207 HydrophobicContact CG-CG 4.17Å; M191-F207 HydrophobicContact CG-CZ 3.93Å; M191-F207 HydrophobicContact SD-CB 4.46Å; M191-F207 HydrophobicContact SD-CD1 4.37Å; M191-F207 HydrophobicContact SD-CD2 4.2Å; M191-F207 HydrophobicContact SD-CG 4.09Å; M191-L209 HydrophobicContact SD-CD2 4.31Å; M191-I218 HydrophobicContact CE-CG1 4.42Å; M191-I218 HydrophobicContact CE-CG2 4.22Å; M191-F220 HydrophobicContact SD-CE1 4.28Å; M191-I223 HydrophobicContact CB-CD1 4.09Å; M191-I223 HydrophobicContact CB-CG1 4.45Å; M191-I223 HydrophobicContact CB-CG2 3.79Å; M191-I223 HydrophobicContact CE-CD1 3.66Å; M191-I223 HydrophobicContact SD-CD1 4.37Å
192K98.4Very high97.3Very high71 Ų7141 Ų4131%0.30920%0.196SC..Hα-helixtrans-66.4-53.4-178.2-177.3-177.8176.5-178.60109.7D190 L194 T195 E196 E222 I223D190-K192 PolarHBondContact O-N 3.29Å; D190-K192 VanDerWaalsContact O-N 3.17Å; D190-K192 PolarHBondContact OD1-N 3.32Å; K192-L194 VanDerWaalsContact C-N 3.33Å; K192-L194 PolarHBondContact O-N 2.68Å; K192-T195 PolarHBondContact O-N 3.09Å; K192-E196 WeakPolarHBondContact CE-OE1 3.46Å; K192-E196 WeakPolarHBondContact O-CG 2.99Å; K192-E196 PolarHBondContact O-N 2.93Å; K192-E222 HydrophobicContact CD-CG 4.12Å; K192-E222 WeakPolarHBondContact CE-OE1 3.19Å; K192-E222 IonicContact NZ-OE1 3.25Å; K192-E222 PolarHBondContact NZ-OE1 2.93Å; K192-I223 HydrophobicContact CB-CG1 4.13Å
193R98.4Very high97.4Very high90 Ų9041 Ų4134%0.3420%0.196SC..Hα-helixtrans-55.8-48.5178.1-178.5-175.6-178.7-151.6-4.5111.5E162 D163 I166 D190 T195 E196 E197E162-R193 IonicContact OE2-NH1 2.97Å; D163-R193 IonicContact OD1-CZ 3.86Å; D163-R193 IonicContact OD1-NH1 2.7Å; D163-R193 PolarHBondContact OD1-NH1 2.95Å; D163-R193 IonicContact OD1-NH2 3.98Å; D163-R193 PolarHBondContact OD1-NH2 2.79Å; I166-R193 HydrophobicContact CD1-CG 4.22Å; D190-R193 HydrophobicContact CB-CB 3.97Å; D190-R193 PolarHBondContact O-N 2.84Å; D190-R193 PolarHBondContact OD1-N 2.72Å; D190-R193 WeakPolarHBondContact OD2-CB 3.43Å; R193-T195 PolarHBondContact O-N 3.02Å; R193-E196 PolarHBondContact O-N 2.83Å; R193-E197 WeakPolarHBondContact O-CG 3.36Å; R193-E197 PolarHBondContact O-N 2.85Å; R193-E197 VanDerWaalsContact O-N 3.08Å
194L98.6Very high97.7Very high0 Ų040.4 Ų40.40%020%0.196CC..Hα-helixtrans-65.3-38.3-179.7-66173.4000112.2E162 V165 I166 M169 L178 I189 D190 K192 A198 I205 F207E162-L194 HydrophobicContact CB-CD2 4.44Å; V165-L194 HydrophobicContact CB-CD2 4.13Å; V165-L194 HydrophobicContact CG1-CD2 3.77Å; I166-L194 HydrophobicContact CD1-CD2 4.29Å; I166-L194 HydrophobicContact CG1-CD2 3.87Å; M169-L194 HydrophobicContact CE-CB 4.44Å; M169-L194 HydrophobicContact CE-CD2 3.99Å; L178-L194 HydrophobicContact CD1-CD1 4.02Å; I189-L194 HydrophobicContact CB-CD1 4.24Å; I189-L194 HydrophobicContact CD1-CD1 3.84Å; I189-L194 HydrophobicContact CG1-CD1 4.39Å; D190-L194 WeakPolarHBondContact O-CG 3.29Å; D190-L194 PolarHBondContact O-N 3.06Å; K192-L194 VanDerWaalsContact C-N 3.33Å; K192-L194 PolarHBondContact O-N 2.68Å; L194-A198 WeakPolarHBondContact O-CB 3.29Å; L194-A198 PolarHBondContact O-N 3.34Å; L194-I205 HydrophobicContact CB-CD1 4.1Å; L194-F207 HydrophobicContact CB-CZ 4.44Å
195T98.8Very high98Very high1 Ų138.5 Ų38.51%0.00619%0.189CC..Hα-helixtrans-67.2-44.7177.5-58.30000112M191 K192 R193 E197 A198 H199 I205 F207 I223M191-T195 WeakPolarHBondContact O-CB 3.46Å; M191-T195 PolarHBondContact O-N 3.39Å; M191-T195 PolarHBondContact O-OG1 2.81Å; K192-T195 PolarHBondContact O-N 3.09Å; R193-T195 PolarHBondContact O-N 3.02Å; T195-E197 PolarHBondContact O-N 2.95Å; T195-A198 PolarHBondContact O-N 3Å; T195-H199 WeakPolarHBondContact CG2-CE1 3.47Å; T195-H199 WeakPolarHBondContact O-CB 3.32Å; T195-H199 PolarHBondContact O-N 3.31Å; T195-I205 HydrophobicContact CG2-CG2 3.85Å; T195-F207 WeakPolarHBondContact OG1-CE2 3.29Å; T195-I223 WeakPolarHBondContact CG2-O 3.2Å
196E98.6Very high98.2Very high91 Ų9138.4 Ų38.443%0.42519%0.188SC..Hα-helixtrans-60.5-43.7176.6-72.2178.4-178.700111.8K192 R193 K200K192-E196 WeakPolarHBondContact CE-OE1 3.46Å; K192-E196 WeakPolarHBondContact O-CG 2.99Å; K192-E196 PolarHBondContact O-N 2.93Å; R193-E196 PolarHBondContact O-N 2.83Å; E196-K200 WeakPolarHBondContact O-CG 3.43Å; E196-K200 PolarHBondContact O-N 3.45Å
197E98.7Very high98.3Very high39 Ų3938.4 Ų38.418%0.18219%0.188CC..Hα-helixtrans-67.4-39177.5-71.1-58128.200112.9I166 M169 R193 T195 K200 R201I166-E197 HydrophobicContact CD1-CG 4.04Å; I166-E197 HydrophobicContact CG1-CB 4.21Å; I166-E197 HydrophobicContact CG1-CG 4.08Å; I166-E197 HydrophobicContact CG2-CB 4.33Å; I166-E197 HydrophobicContact CG2-CG 4.08Å; M169-E197 HydrophobicContact CE-CB 4.35Å; M169-E197 HydrophobicContact SD-CB 3.9Å; R193-E197 WeakPolarHBondContact O-CG 3.36Å; R193-E197 PolarHBondContact O-N 2.85Å; R193-E197 VanDerWaalsContact O-N 3.08Å; T195-E197 PolarHBondContact O-N 2.95Å; E197-K200 IonicContact OE1-NZ 2.67Å; E197-K200 PolarHBondContact OE1-NZ 3.26Å; E197-R201 PolarHBondContact O-NH1 3.25Å; E197-R201 IonicContact OE2-CZ 3.24Å; E197-R201 IonicContact OE2-NH1 3.97Å; E197-R201 PolarHBondContact OE2-NH1 3.42Å; E197-R201 IonicContact OE2-NH2 2.87Å; E197-R201 PolarHBondContact OE2-NH2 3.03Å
198A98.7Very high98.4Very high0 Ų037.8 Ų37.80%019%0.186CC..Hα-helixtrans-64.1-46.8175.400000111.4M169 I176 L194 T195 K200 R201 G202 I203 I205M169-A198 HydrophobicContact CE-CB 4.39Å; M169-A198 HydrophobicContact SD-CB 4.05Å; I176-A198 HydrophobicContact CD1-CB 4Å; L194-A198 WeakPolarHBondContact O-CB 3.29Å; L194-A198 PolarHBondContact O-N 3.34Å; T195-A198 PolarHBondContact O-N 3Å; A198-K200 PolarHBondContact O-N 2.82Å; A198-R201 CarbonylContact O-C 3.56Å; A198-R201 PolarHBondContact O-N 3.07Å; A198-G202 PolarHBondContact O-N 3.22Å; A198-I203 HydrophobicContact CB-CB 4.21Å; A198-I203 PolarHBondContact O-N 3.24Å; A198-I205 HydrophobicContact CB-CB 3.95Å; A198-I205 HydrophobicContact CB-CD1 4.05Å; A198-I205 HydrophobicContact CB-CG2 4Å
199H98.4Very high98.4Very high64 Ų6436.6 Ų36.630%0.29618%0.179SC..Hα-helixtrans-66.5-35.6-179.5-71.7176.1000113.1T195 R201 G202 Q224 D226 K251T195-H199 WeakPolarHBondContact CG2-CE1 3.47Å; T195-H199 WeakPolarHBondContact O-CB 3.32Å; T195-H199 PolarHBondContact O-N 3.31Å; H199-R201 PolarHBondContact O-N 2.82Å; H199-R201 VanDerWaalsContact O-N 3.1Å; H199-G202 PolarHBondContact O-N 3.48Å; H199-Q224 PolarHBondContact CE1-O 2.75Å; H199-Q224 VanDerWaalsContact CE1-O 3.27Å; H199-D226 IonicContact CD2-OD2 2.71Å; H199-D226 IonicContact CE1-OD2 3.08Å; H199-D226 IonicContact NE2-OD1 2.87Å; H199-D226 IonicContact NE2-OD2 3.47Å; H199-D226 PolarHBondContact NE2-OD2 3.12Å; H199-K251 PolarHBondContact CE1-NZ 2.88Å; H199-K251 PolarHBondContact NE2-NZ 2.92Å
200K98.3Very high98.4Very high139 Ų13936.7 Ų36.760%0.60418%0.18SC*.Hα-helixtrans-55.3-26.6171.6-75.7168.2-163.51720112.7E196 E197 A198E196-K200 WeakPolarHBondContact O-CG 3.43Å; E196-K200 PolarHBondContact O-N 3.45Å; E197-K200 IonicContact OE1-NZ 2.67Å; E197-K200 PolarHBondContact OE1-NZ 3.26Å; A198-K200 PolarHBondContact O-N 2.82Å
201R98.1Very high98.4Very high81 Ų8133.5 Ų33.531%0.30616%0.163SC..THydrogen-bonded Turntrans-105.46.1-178.4-64.5164178.174.4-4.4113.4R117 M169 E197 A198 H199 I203R117-R201 PolarHBondContact NH1-O 3.22Å; R117-R201 PolarHBondContact NH2-O 2.99Å; M169-R201 WeakPolarHBondContact O-CD 3.3Å; M169-R201 PolarHBondContact O-NE 2.86Å; E197-R201 PolarHBondContact O-NH1 3.25Å; E197-R201 IonicContact OE2-CZ 3.24Å; E197-R201 IonicContact OE2-NH1 3.97Å; E197-R201 PolarHBondContact OE2-NH1 3.42Å; E197-R201 IonicContact OE2-NH2 2.87Å; E197-R201 PolarHBondContact OE2-NH2 3.03Å; A198-R201 CarbonylContact O-C 3.56Å; A198-R201 PolarHBondContact O-N 3.07Å; H199-R201 PolarHBondContact O-N 2.82Å; H199-R201 VanDerWaalsContact O-N 3.1Å; R201-I203 VanDerWaalsContact C-N 3.27Å; R201-I203 HydrophobicContact CB-CD1 3.78Å; R201-I203 HydrophobicContact CB-CG1 3.91Å; R201-I203 PolarHBondContact O-N 3.27Å
202G97.6Very high98.4Very high57 Ų5733 Ų3359%0.58816%0.16SC*.THydrogen-bonded Turntrans66.524.8-178.600000114.3A198 H199A198-G202 PolarHBondContact O-N 3.22Å; H199-G202 PolarHBondContact O-N 3.48Å
203I98.6Very high98.4Very high2 Ų229.8 Ų29.81%0.0115%0.146CC..  trans-90.4135.1-179.1-55.2169.2000109.2M169 V173 I176 A198 R201M169-I203 HydrophobicContact CB-CD1 3.72Å; M169-I203 HydrophobicContact CG-CD1 4.3Å; V173-I203 HydrophobicContact CB-CD1 4.12Å; V173-I203 HydrophobicContact CG1-CD1 4.33Å; V173-I203 HydrophobicContact CG1-CG2 3.82Å; I176-I203 HydrophobicContact CD1-CG2 3.87Å; I176-I203 HydrophobicContact CG1-CG2 3.6Å; A198-I203 HydrophobicContact CB-CB 4.21Å; A198-I203 PolarHBondContact O-N 3.24Å; R201-I203 VanDerWaalsContact C-N 3.27Å; R201-I203 HydrophobicContact CB-CD1 3.78Å; R201-I203 HydrophobicContact CB-CG1 3.91Å; R201-I203 PolarHBondContact O-N 3.27Å
204I98.7Very high98.3Very high33 Ų3325.7 Ų25.717%0.16913%0.133CC..EExtended strand (participates in β ladder)trans-74.2130.8170.9-58.3-60.2000108.7F110 A174 V175 I176 D226 F227F110-I204 HydrophobicContact CB-CG2 3.87Å; F110-I204 HydrophobicContact CD1-CD1 4.31Å; F110-I204 HydrophobicContact CD1-CG1 4.36Å; F110-I204 HydrophobicContact CD1-CG2 3.89Å; F110-I204 HydrophobicContact CG-CG2 3.85Å; A174-I204 PolarHBondContact O-N 2.89Å; A174-I204 VanDerWaalsContact O-N 3.16Å; V175-I204 CarbonylContact C-O 3.5Å; V175-I204 WeakPolarHBondContact CA-O 3.44Å; V175-I204 HydrophobicContact CG2-CB 4.27Å; I176-I204 PolarHBondContact N-O 2.95Å; I204-D226 WeakPolarHBondContact CA-OD2 3.43Å; I204-D226 HydrophobicContact CG2-CB 3.61Å; I204-F227 HydrophobicContact CG2-CD1 4.09Å; I204-F227 HydrophobicContact CG2-CE1 3.99Å
205I98.8Very high98.3Very high0 Ų025.9 Ų25.90%013%0.134CC..EExtended strand (participates in β ladder)trans-125134.8177.5-175.3161.5000111.2I176 L194 T195 A198 F207 D226I176-I205 HydrophobicContact CB-CB 4.27Å; I176-I205 HydrophobicContact CB-CD1 4.28Å; I176-I205 HydrophobicContact CB-CG1 3.98Å; I176-I205 HydrophobicContact CD1-CD1 4.37Å; I176-I205 HydrophobicContact CG2-CD1 4.17Å; I176-I205 HydrophobicContact CG2-CG1 4.2Å; L194-I205 HydrophobicContact CB-CD1 4.1Å; T195-I205 HydrophobicContact CG2-CG2 3.85Å; A198-I205 HydrophobicContact CB-CB 3.95Å; A198-I205 HydrophobicContact CB-CD1 4.05Å; A198-I205 HydrophobicContact CB-CG2 4Å; I205-F207 HydrophobicContact CD1-CE1 4.25Å; I205-F207 HydrophobicContact CD1-CE2 4.13Å; I205-F207 HydrophobicContact CD1-CZ 3.58Å; I205-F207 HydrophobicContact CG1-CE1 4.46Å; I205-F207 HydrophobicContact CG1-CE2 3.92Å; I205-F207 HydrophobicContact CG1-CZ 3.81Å; I205-D226 PolarHBondContact N-OD2 3.03Å; I205-D226 WeakPolarHBondContact O-CB 3.45Å; I205-D226 PolarHBondContact O-N 2.98Å
206G98.7Very high98.2Very high0 Ų026.3 Ų26.30%014%0.136CC..EExtended strand (participates in β ladder)trans-136.9164.717000000113.3I176 L177 L178 F227I176-G206 PolarHBondContact O-N 2.88Å; L177-G206 WeakPolarHBondContact CA-O 3.22Å; L178-G206 PolarHBondContact N-O 3.32Å; G206-F227 WeakPolarHBondContact CA-O 3.41Å
207F98.7Very high98.2Very high0 Ų026.7 Ų26.70%014%0.138CC..EExtended strand (participates in β ladder)trans-130.3142.8-173.2-62.3-81.6000113L178 T180 I189 M191 L194 T195 I205 L209 P225 F227 A228 V229L178-F207 HydrophobicContact CB-CD1 4.2Å; L178-F207 HydrophobicContact CB-CE1 4.3Å; L178-F207 CarbonylContact O-C 3.57Å; L178-F207 WeakPolarHBondContact O-CA 3.34Å; T180-F207 WeakPolarHBondContact OG1-CB 3.46Å; I189-F207 HydrophobicContact CD1-CD1 3.93Å; I189-F207 HydrophobicContact CD1-CE1 3.71Å; M191-F207 HydrophobicContact CB-CE1 4.2Å; M191-F207 HydrophobicContact CB-CE2 4.06Å; M191-F207 HydrophobicContact CB-CZ 3.84Å; M191-F207 HydrophobicContact CG-CD1 3.92Å; M191-F207 HydrophobicContact CG-CD2 4.3Å; M191-F207 HydrophobicContact CG-CE1 3.79Å; M191-F207 HydrophobicContact CG-CE2 4.18Å; M191-F207 HydrophobicContact CG-CG 4.17Å; M191-F207 HydrophobicContact CG-CZ 3.93Å; M191-F207 HydrophobicContact SD-CB 4.46Å; M191-F207 HydrophobicContact SD-CD1 4.37Å; M191-F207 HydrophobicContact SD-CD2 4.2Å; M191-F207 HydrophobicContact SD-CG 4.09Å; L194-F207 HydrophobicContact CB-CZ 4.44Å; T195-F207 WeakPolarHBondContact OG1-CE2 3.29Å; I205-F207 HydrophobicContact CD1-CE1 4.25Å; I205-F207 HydrophobicContact CD1-CE2 4.13Å; I205-F207 HydrophobicContact CD1-CZ 3.58Å; I205-F207 HydrophobicContact CG1-CE1 4.46Å; I205-F207 HydrophobicContact CG1-CE2 3.92Å; I205-F207 HydrophobicContact CG1-CZ 3.81Å; F207-L209 HydrophobicContact CB-CD2 3.83Å; F207-P225 HydrophobicContact CD2-CB 3.77Å; F207-P225 HydrophobicContact CE2-CB 3.88Å; F207-F227 PolarHBondContact N-O 2.51Å; F207-A228 CarbonylContact O-C 3.52Å; F207-A228 WeakPolarHBondContact O-CA 3.22Å; F207-A228 WeakPolarHBondContact O-CB 3.41Å; F207-V229 PolarHBondContact O-N 2.79Å
208D98.5Very high98.1Very high10 Ų1025.3 Ų25.35%0.05313%0.132CC..EExtended strand (participates in β ladder)trans-88.4115.8162.6-179.716.5000110.4D130 L178 T180 C210 V229D130-D208 WeakPolarHBondContact OD1-CB 3.15Å; L178-D208 PolarHBondContact O-N 2.97Å; T180-D208 PolarHBondContact N-O 3.31Å; D208-C210 VanDerWaalsContact OD1-CB 3.3Å; D208-C210 WeakPolarHBondContact OD1-CB 3.42Å; D208-C210 PolarHBondContact OD1-N 2.84Å; D208-C210 PolarHBondContact OD1-SG 2.88Å; D208-V229 HydrophobicContact CB-CG2 4.16Å
209L98.6Very high98.1Very high0 Ų027.8 Ų27.80%015%0.145CC..  trans-95.810.3179.1-32.8178.3000112.7I86 T180 M191 F207 H211 A212 I213 I218 F220 A228 V229 W230I86-L209 HydrophobicContact CG2-CD1 4Å; T180-L209 HydrophobicContact CG2-CD2 4.43Å; T180-L209 WeakPolarHBondContact OG1-CD2 3.03Å; M191-L209 HydrophobicContact SD-CD2 4.31Å; F207-L209 HydrophobicContact CB-CD2 3.83Å; L209-H211 PolarHBondContact O-N 3.21Å; L209-A212 HydrophobicContact CB-CB 4.14Å; L209-A212 WeakPolarHBondContact O-CA 3.2Å; L209-A212 PolarHBondContact O-N 3.37Å; L209-I213 HydrophobicContact CB-CB 4.2Å; L209-I213 WeakPolarHBondContact O-CG2 3.18Å; L209-I213 PolarHBondContact O-N 2.81Å; L209-I218 HydrophobicContact CD1-CD1 4.18Å; L209-F220 HydrophobicContact CD1-CE2 4.07Å; L209-F220 HydrophobicContact CD1-CZ 3.59Å; L209-F220 HydrophobicContact CD2-CZ 4.01Å; L209-F220 HydrophobicContact CG-CZ 4.37Å; L209-A228 HydrophobicContact CD1-CB 4.09Å; L209-A228 HydrophobicContact CD2-CB 4.25Å; L209-A228 HydrophobicContact CG-CB 4.09Å; L209-V229 PolarHBondContact N-O 3.42Å; L209-W230 HydrophobicContact CB-CB 3.89Å; L209-W230 HydrophobicContact CD1-CD2 4.23Å; L209-W230 HydrophobicContact CD1-CE3 3.53Å; L209-W230 HydrophobicContact CD1-CZ3 3.97Å; L209-W230 HydrophobicContact CG-CE3 4.03Å
210C97.9Very high98.1Very high5 Ų524.8 Ų24.83%0.03413%0.131CC..THydrogen-bonded Turntrans-51-37.3-174.5-80.40000114.4T99 D208 C231 K234T99-C210 VanDerWaalsContact CG2-SG 3.52Å; T99-C210 PolarHBondContact OG1-SG 3.48Å; D208-C210 VanDerWaalsContact OD1-CB 3.3Å; D208-C210 WeakPolarHBondContact OD1-CB 3.42Å; D208-C210 PolarHBondContact OD1-N 2.84Å; D208-C210 PolarHBondContact OD1-SG 2.88Å; C210-C231 PolarHBondContact SG-N 3.42Å; C210-K234 HydrophobicContact CB-CD 4.38Å; C210-K234 VanDerWaalsContact O-CD 3.22Å; C210-K234 WeakPolarHBondContact O-CD 3Å
211H97.4Very high98.1Very high9 Ų923.9 Ų23.94%0.04213%0.127CC..THydrogen-bonded Turntrans-980.6175.8-82.4-76.1000114.2N40 V181 Y183 L209 K234 Y235 R383N40-H211 PolarHBondContact O-CE1 3.41Å; N40-H211 PolarHBondContact O-ND1 2.94Å; V181-H211 HydrophobicContact CB-CB 3.83Å; V181-H211 HydrophobicContact CG1-CB 3.82Å; Y183-H211 WeakPolarHBondContact CB-CD2 3.41Å; Y183-H211 VanDerWaalsContact CB-NE2 3.32Å; Y183-H211 WeakPolarHBondContact CB-NE2 3.22Å; L209-H211 PolarHBondContact O-N 3.21Å; H211-K234 PolarHBondContact CD2-NZ 3.26Å; H211-K234 VanDerWaalsContact CD2-NZ 3.31Å; H211-K234 PolarHBondContact NE2-NZ 3.09Å; H211-Y235 WeakPolarHBondContact O-CE2 3.48Å; H211-R383 PolarHBondContact CE1-NH1 3.48Å
212A98.1Very high98.1Very high0 Ų025.3 Ų25.30%014%0.137CC..THydrogen-bonded Turntrans-106.6-45.3-176.800000112.5T180 V181 L209 G214 A215 I216 I218T180-A212 HydrophobicContact CG2-CB 3.56Å; V181-A212 HydrophobicContact CB-CB 4.28Å; V181-A212 HydrophobicContact CG2-CB 3.71Å; L209-A212 HydrophobicContact CB-CB 4.14Å; L209-A212 WeakPolarHBondContact O-CA 3.2Å; L209-A212 PolarHBondContact O-N 3.37Å; A212-G214 PolarHBondContact O-N 3.16Å; A212-A215 WeakPolarHBondContact O-CB 3.25Å; A212-A215 PolarHBondContact O-N 2.9Å; A212-I216 HydrophobicContact CB-CD1 3.98Å; A212-I216 HydrophobicContact CB-CG1 4Å; A212-I216 PolarHBondContact O-N 2.79Å; A212-I218 HydrophobicContact CB-CD1 4.04Å
213I98.2Very high98.1Very high4 Ų423.5 Ų23.52%0.02111%0.114CC..THydrogen-bonded Turntrans-61.8126.2-176.9-165.371.4000110.4L85 I86 L209 A215 W230 L236L85-I213 HydrophobicContact CB-CD1 3.74Å; L85-I213 HydrophobicContact CD1-CD1 4.21Å; L85-I213 HydrophobicContact CD1-CG1 4.31Å; I86-I213 HydrophobicContact CG2-CD1 3.39Å; L209-I213 HydrophobicContact CB-CB 4.2Å; L209-I213 WeakPolarHBondContact O-CG2 3.18Å; L209-I213 PolarHBondContact O-N 2.81Å; I213-A215 PolarHBondContact O-N 3Å; I213-W230 HydrophobicContact CB-CB 4.39Å; I213-W230 HydrophobicContact CB-CG 4.28Å; I213-W230 HydrophobicContact CG1-CG 4.34Å; I213-W230 HydrophobicContact CG2-CB 3.86Å; I213-W230 HydrophobicContact CG2-CG 3.97Å; I213-L236 HydrophobicContact CB-CD1 4.5Å; I213-L236 HydrophobicContact CG1-CD1 3.69Å; I213-L236 HydrophobicContact CG1-CD2 4.47Å; I213-L236 HydrophobicContact CG1-CG 4.23Å; I213-L236 HydrophobicContact CG2-CD1 4.02Å; I213-L236 HydrophobicContact CG2-CG 4.22Å
214G97.2Very high98.1Very high5 Ų526.2 Ų26.25%0.05213%0.127CC..THydrogen-bonded Turntrans77.3-3.3-174.300000115.3A212 M311A212-G214 PolarHBondContact O-N 3.16Å; G214-M311 VanDerWaalsContact C-CE 3.46Å
215A97.1Very high98.1Very high4 Ų424.6 Ų24.63%0.03312%0.119CC..THydrogen-bonded Turntrans-111.8-37.9178.700000113.8A212 I213 Y235 R315A212-A215 WeakPolarHBondContact O-CB 3.25Å; A212-A215 PolarHBondContact O-N 2.9Å; I213-A215 PolarHBondContact O-N 3Å; A215-Y235 HydrophobicContact CB-CD1 3.86Å; A215-Y235 HydrophobicContact CB-CD2 3.68Å; A215-Y235 HydrophobicContact CB-CE1 3.9Å; A215-Y235 HydrophobicContact CB-CE2 3.71Å; A215-Y235 HydrophobicContact CB-CG 3.75Å; A215-R315 WeakPolarHBondContact O-CD 3.03Å
216I97.4Very high98.1Very high9 Ų924.8 Ų24.85%0.04612%0.119CC..SBendtrans-124.4160.4-179.871.4171.3000110.9T180 V181 I188 A212 I218 M311T180-I216 HydrophobicContact CG2-CD1 3.97Å; V181-I216 HydrophobicContact CG2-CD1 4.01Å; I188-I216 HydrophobicContact CD1-CD1 4.41Å; I188-I216 HydrophobicContact CD1-CG2 3.86Å; I188-I216 HydrophobicContact CG1-CD1 4.36Å; I188-I216 HydrophobicContact CG1-CG2 4.37Å; I188-I216 HydrophobicContact CG2-CD1 3.96Å; A212-I216 HydrophobicContact CB-CD1 3.98Å; A212-I216 HydrophobicContact CB-CG1 4Å; A212-I216 PolarHBondContact O-N 2.79Å; I216-I218 HydrophobicContact CD1-CG1 4.33Å; I216-I218 HydrophobicContact CG1-CD1 4.3Å; I216-I218 HydrophobicContact CG1-CG1 3.9Å; I216-M311 WeakPolarHBondContact O-CE 3.47Å
217E97.7Very high98.1Very high99 Ų9924.8 Ų24.846%0.46312%0.119SC..  trans-74.8134.5169.7-65.8-177.3-114.200109.7M311 K312 R315E217-M311 HydrophobicContact CG-CB 4.18Å; E217-K312 WeakPolarHBondContact OE2-CE 3.42Å; E217-K312 WeakPolarHBondContact OE2-CG 3.38Å; E217-R315 HydrophobicContact CG-CB 4.2Å; E217-R315 HydrophobicContact CG-CG 4.46Å
218I98.3Very high98.1Very high11 Ų1124.8 Ų24.86%0.05612%0.119CC..  trans-130.5133.2-178.7-60.5174.4000108.3I86 M191 L209 A212 I216 F220I86-I218 CarbonylContact C-O 3.57Å; I86-I218 WeakPolarHBondContact CA-O 3.4Å; I86-I218 HydrophobicContact CB-CB 4.42Å; I86-I218 HydrophobicContact CB-CG2 4.02Å; I86-I218 HydrophobicContact CG2-CB 4.16Å; I86-I218 HydrophobicContact CG2-CD1 4.2Å; I86-I218 HydrophobicContact CG2-CG2 3.94Å; M191-I218 HydrophobicContact CE-CG1 4.42Å; M191-I218 HydrophobicContact CE-CG2 4.22Å; L209-I218 HydrophobicContact CD1-CD1 4.18Å; A212-I218 HydrophobicContact CB-CD1 4.04Å; I216-I218 HydrophobicContact CD1-CG1 4.33Å; I216-I218 HydrophobicContact CG1-CD1 4.3Å; I216-I218 HydrophobicContact CG1-CG1 3.9Å; I218-F220 HydrophobicContact CG2-CD1 3.38Å; I218-F220 HydrophobicContact CG2-CE1 3.25Å; I218-F220 HydrophobicContact CG2-CG 4.29Å; I218-F220 HydrophobicContact CG2-CZ 4.05Å
219D98.2Very high98.1Very high52 Ų5224.3 Ų24.328%0.27812%0.117SC..  trans-125.190.7178.4-164.8-26.6000112.2N87 K221 E222 I223N87-D219 HydrophobicContact CB-CB 4.44Å; N87-D219 PolarHBondContact ND2-OD1 3.46Å; N87-D219 PolarHBondContact ND2-OD2 3.48Å; D219-K221 VanDerWaalsContact C-N 3.33Å; D219-K221 WeakPolarHBondContact OD1-CB 3.48Å; D219-K221 PolarHBondContact OD1-N 3.26Å; D219-E222 HydrophobicContact CB-CB 4.22Å; D219-E222 PolarHBondContact O-N 3.25Å; D219-E222 PolarHBondContact OD1-N 3.47Å; D219-E222 VanDerWaalsContact OD1-N 3.08Å; D219-I223 WeakPolarHBondContact O-CB 3.4Å; D219-I223 WeakPolarHBondContact O-CD1 3.3Å; D219-I223 WeakPolarHBondContact O-CG1 3.31Å; D219-I223 PolarHBondContact O-N 2.98Å
220F98.6Very high98.1Very high1 Ų124.3 Ų24.30%0.00412%0.117CC..Hα-helixtrans-77.4-15.4178.1-75.83.4000113.9I86 A88 M191 L209 I218 E222 I223 Q224 P225 A228 Y247I86-F220 HydrophobicContact CB-CD2 4.11Å; I86-F220 HydrophobicContact CB-CE2 4.35Å; I86-F220 HydrophobicContact CB-CG 4.27Å; I86-F220 HydrophobicContact CD1-CD2 3.66Å; I86-F220 HydrophobicContact CD1-CE2 3.87Å; I86-F220 HydrophobicContact CG1-CD2 4.32Å; I86-F220 WeakPolarHBondContact O-CB 3.47Å; I86-F220 PolarHBondContact O-N 2.86Å; A88-F220 HydrophobicContact CB-CB 4.35Å; M191-F220 HydrophobicContact SD-CE1 4.28Å; L209-F220 HydrophobicContact CD1-CE2 4.07Å; L209-F220 HydrophobicContact CD1-CZ 3.59Å; L209-F220 HydrophobicContact CD2-CZ 4.01Å; L209-F220 HydrophobicContact CG-CZ 4.37Å; I218-F220 HydrophobicContact CG2-CD1 3.38Å; I218-F220 HydrophobicContact CG2-CE1 3.25Å; I218-F220 HydrophobicContact CG2-CG 4.29Å; I218-F220 HydrophobicContact CG2-CZ 4.05Å; F220-E222 PolarHBondContact O-N 3.31Å; F220-I223 HydrophobicContact CD1-CB 4.39Å; F220-I223 HydrophobicContact CD1-CD1 4.15Å; F220-I223 HydrophobicContact CE1-CD1 4.42Å; F220-Q224 WeakPolarHBondContact O-CA 3.47Å; F220-Q224 PolarHBondContact O-N 2.8Å; F220-Q224 PolarHBondContact O-NE2 3.06Å; F220-P225 HydrophobicContact CD1-CG 3.96Å; F220-P225 HydrophobicContact CD2-CG 4Å; F220-P225 HydrophobicContact CE1-CG 3.86Å; F220-P225 HydrophobicContact CE2-CG 3.93Å; F220-P225 HydrophobicContact CG-CG 4.03Å; F220-P225 HydrophobicContact CZ-CG 3.84Å; F220-A228 HydrophobicContact CE2-CB 3.68Å; F220-A228 HydrophobicContact CZ-CB 3.72Å; F220-Y247 HydrophobicContact CB-CE2 4.42Å; F220-Y247 AromaticContact CD2-CD1 3.82Å; F220-Y247 HydrophobicContact CD2-CD1 3.82Å; F220-Y247 AromaticContact CD2-CD2 3.8Å; F220-Y247 HydrophobicContact CD2-CD2 3.8Å; F220-Y247 AromaticContact CD2-CE1 3.87Å; F220-Y247 HydrophobicContact CD2-CE1 3.87Å; F220-Y247 AromaticContact CD2-CE2 3.81Å; F220-Y247 HydrophobicContact CD2-CE2 3.81Å; F220-Y247 AromaticContact CD2-CG 3.8Å; F220-Y247 HydrophobicContact CD2-CG 3.8Å; F220-Y247 AromaticContact CD2-CZ 3.85Å; F220-Y247 AromaticContact CE2-CD1 3.83Å; F220-Y247 HydrophobicContact CE2-CD1 3.83Å; F220-Y247 HydrophobicContact CE2-CD2 4.29Å; F220-Y247 HydrophobicContact CE2-CE1 4.26Å; F220-Y247 AromaticContact CE2-CG 3.85Å; F220-Y247 HydrophobicContact CE2-CG 3.85Å
221K97.6Very high98.2Very high120 Ų12024.1 Ų24.152%0.52212%0.116SC..Hα-helixtrans-64.7-35.1166.2-84.1166.3-164.6159.50111.1N87 D219 Q224N87-K221 WeakPolarHBondContact O-CD 3.2Å; N87-K221 WeakPolarHBondContact O-CE 3.48Å; N87-K221 WeakPolarHBondContact O-CG 3.43Å; N87-K221 PolarHBondContact O-N 3.31Å; N87-K221 PolarHBondContact OD1-NZ 2.79Å; D219-K221 VanDerWaalsContact C-N 3.33Å; D219-K221 WeakPolarHBondContact OD1-CB 3.48Å; D219-K221 PolarHBondContact OD1-N 3.26Å; K221-Q224 WeakPolarHBondContact O-CG 3.4Å; K221-Q224 PolarHBondContact O-NE2 2.78Å
222E98Very high98.2Very high110 Ų11023.7 Ų23.751%0.51411%0.114SC..Hα-helixtrans-84.7-49.5176.7-172.2174.9-173.900112.7K192 D219 F220K192-E222 HydrophobicContact CD-CG 4.12Å; K192-E222 WeakPolarHBondContact CE-OE1 3.19Å; K192-E222 IonicContact NZ-OE1 3.25Å; K192-E222 PolarHBondContact NZ-OE1 2.93Å; D219-E222 HydrophobicContact CB-CB 4.22Å; D219-E222 PolarHBondContact O-N 3.25Å; D219-E222 PolarHBondContact OD1-N 3.47Å; D219-E222 VanDerWaalsContact OD1-N 3.08Å; F220-E222 PolarHBondContact O-N 3.31Å
223I98.4Very high98.2Very high19 Ų1927.1 Ų27.110%0.09713%0.127CC..Hα-helixtrans-70.7-39.9-174.4-63.2160000111.5M191 K192 T195 D219 F220 P225M191-I223 HydrophobicContact CB-CD1 4.09Å; M191-I223 HydrophobicContact CB-CG1 4.45Å; M191-I223 HydrophobicContact CB-CG2 3.79Å; M191-I223 HydrophobicContact CE-CD1 3.66Å; M191-I223 HydrophobicContact SD-CD1 4.37Å; K192-I223 HydrophobicContact CB-CG1 4.13Å; T195-I223 WeakPolarHBondContact CG2-O 3.2Å; D219-I223 WeakPolarHBondContact O-CB 3.4Å; D219-I223 WeakPolarHBondContact O-CD1 3.3Å; D219-I223 WeakPolarHBondContact O-CG1 3.31Å; D219-I223 PolarHBondContact O-N 2.98Å; F220-I223 HydrophobicContact CD1-CB 4.39Å; F220-I223 HydrophobicContact CD1-CD1 4.15Å; F220-I223 HydrophobicContact CE1-CD1 4.42Å; I223-P225 HydrophobicContact CG2-CG 4.4Å
224Q98.4Very high98.1Very high59 Ų5927.8 Ų27.828%0.27613%0.13SC..  trans52.647.3-179.3-68.9-72.9-61.700115.1H199 F220 K221 N249H199-Q224 PolarHBondContact CE1-O 2.75Å; H199-Q224 VanDerWaalsContact CE1-O 3.27Å; F220-Q224 WeakPolarHBondContact O-CA 3.47Å; F220-Q224 PolarHBondContact O-N 2.8Å; F220-Q224 PolarHBondContact O-NE2 3.06Å; K221-Q224 WeakPolarHBondContact O-CG 3.4Å; K221-Q224 PolarHBondContact O-NE2 2.78Å; Q224-N249 PolarHBondContact OE1-ND2 2.99Å
225P98.7Very high98.2Very high0 Ų028 Ų280%013%0.129CC..  trans-61.5162.4175.831.4-33.2000110.4F207 F220 I223 Y247 N249F207-P225 HydrophobicContact CD2-CB 3.77Å; F207-P225 HydrophobicContact CE2-CB 3.88Å; F220-P225 HydrophobicContact CD1-CG 3.96Å; F220-P225 HydrophobicContact CD2-CG 4Å; F220-P225 HydrophobicContact CE1-CG 3.86Å; F220-P225 HydrophobicContact CE2-CG 3.93Å; F220-P225 HydrophobicContact CG-CG 4.03Å; F220-P225 HydrophobicContact CZ-CG 3.84Å; I223-P225 HydrophobicContact CG2-CG 4.4Å; P225-Y247 HydrophobicContact CG-CD1 4.32Å; P225-Y247 HydrophobicContact CG-CE1 3.87Å; P225-Y247 WeakPolarHBondContact O-CE1 3.44Å; P225-N249 VanDerWaalsContact O-CB 3.3Å; P225-N249 WeakPolarHBondContact O-CB 3.42Å; P225-N249 PolarHBondContact O-ND2 2.96Å; P225-N249 VanDerWaalsContact O-ND2 3.11Å
226D98.8Very high98.2Very high3 Ų327.9 Ų27.92%0.01613%0.128CC..SBendtrans-76.2-39.1178.9-63.4-72.7000111.8H199 I204 I205 N249 K251 H252H199-D226 IonicContact CD2-OD2 2.71Å; H199-D226 IonicContact CE1-OD2 3.08Å; H199-D226 IonicContact NE2-OD1 2.87Å; H199-D226 IonicContact NE2-OD2 3.47Å; H199-D226 PolarHBondContact NE2-OD2 3.12Å; I204-D226 WeakPolarHBondContact CA-OD2 3.43Å; I204-D226 HydrophobicContact CG2-CB 3.61Å; I205-D226 PolarHBondContact N-OD2 3.03Å; I205-D226 WeakPolarHBondContact O-CB 3.45Å; I205-D226 PolarHBondContact O-N 2.98Å; D226-N249 WeakPolarHBondContact O-CB 3.4Å; D226-N249 PolarHBondContact O-N 3.1Å; D226-K251 WeakPolarHBondContact OD1-CE 3.3Å; D226-K251 IonicContact OD1-NZ 3.62Å; D226-K251 PolarHBondContact OD1-NZ 3.49Å; D226-H252 WeakPolarHBondContact CB-NE2 3.3Å; D226-H252 IonicContact OD1-CD2 2.87Å; D226-H252 IonicContact OD1-CE1 2.63Å; D226-H252 IonicContact OD1-NE2 2.79Å; D226-H252 PolarHBondContact OD1-NE2 3.48Å
227F98.8Very high98.2Very high0 Ų027.5 Ų27.50%013%0.126CC..EExtended strand (participates in β ladder)trans-149.4164.6172.369-86000111.3A106 F110 V175 L177 I204 G206 F207 Y247 I248A106-F227 HydrophobicContact CB-CD2 3.45Å; A106-F227 VanDerWaalsContact CB-CD2 3.45Å; A106-F227 HydrophobicContact CB-CE2 3.64Å; A106-F227 HydrophobicContact CB-CG 3.94Å; A106-F227 HydrophobicContact CB-CZ 4.27Å; F110-F227 HydrophobicContact CD2-CB 4.34Å; F110-F227 AromaticContact CD2-CD1 3.56Å; F110-F227 HydrophobicContact CD2-CD1 3.56Å; F110-F227 HydrophobicContact CD2-CE1 4.11Å; F110-F227 HydrophobicContact CD2-CG 4.11Å; F110-F227 HydrophobicContact CE2-CB 3.72Å; F110-F227 AromaticContact CE2-CD1 3.78Å; F110-F227 HydrophobicContact CE2-CD1 3.78Å; F110-F227 AromaticContact CE2-CG 3.99Å; F110-F227 HydrophobicContact CE2-CG 3.99Å; F110-F227 HydrophobicContact CG-CD1 4.29Å; F110-F227 HydrophobicContact CZ-CB 4.43Å; V175-F227 HydrophobicContact CG1-CE1 4.14Å; V175-F227 HydrophobicContact CG1-CZ 4.33Å; L177-F227 HydrophobicContact CD1-CE2 4.01Å; L177-F227 HydrophobicContact CD1-CZ 4.25Å; I204-F227 HydrophobicContact CG2-CD1 4.09Å; I204-F227 HydrophobicContact CG2-CE1 3.99Å; G206-F227 WeakPolarHBondContact CA-O 3.41Å; F207-F227 PolarHBondContact N-O 2.51Å; F227-Y247 CarbonylContact C-O 3.53Å; F227-Y247 WeakPolarHBondContact CA-O 3.49Å; F227-Y247 WeakPolarHBondContact CB-O 3.43Å; F227-I248 HydrophobicContact CB-CD1 3.99Å
228A98.9Very high98.1Very high0 Ų023 Ų230%011%0.107CC..EExtended strand (participates in β ladder)trans-151155.9167.200000110.2F207 L209 F220 W230 L246 Y247F207-A228 CarbonylContact O-C 3.52Å; F207-A228 WeakPolarHBondContact O-CA 3.22Å; F207-A228 WeakPolarHBondContact O-CB 3.41Å; L209-A228 HydrophobicContact CD1-CB 4.09Å; L209-A228 HydrophobicContact CD2-CB 4.25Å; L209-A228 HydrophobicContact CG-CB 4.09Å; F220-A228 HydrophobicContact CE2-CB 3.68Å; F220-A228 HydrophobicContact CZ-CB 3.72Å; A228-W230 HydrophobicContact CB-CE3 4.45Å; A228-W230 HydrophobicContact CB-CZ3 4.23Å; A228-L246 CarbonylContact O-C 3.47Å; A228-L246 WeakPolarHBondContact O-CA 3.42Å; A228-Y247 HydrophobicContact CB-CD1 4.33Å; A228-Y247 PolarHBondContact N-O 3.05Å; A228-Y247 PolarHBondContact O-N 3.1Å
229V98.7Very high97.8Very high0 Ų023.9 Ų23.90%012%0.118CC..EExtended strand (participates in β ladder)trans-131.1154179.3-61.10000109.7T99 N102 I103 F207 D208 L209 L246T99-V229 HydrophobicContact CG2-CB 4.37Å; T99-V229 HydrophobicContact CG2-CG2 3.96Å; N102-V229 HydrophobicContact CB-CB 4.34Å; N102-V229 HydrophobicContact CB-CG1 3.81Å; I103-V229 HydrophobicContact CD1-CG2 4.32Å; I103-V229 HydrophobicContact CG1-CB 4.45Å; I103-V229 HydrophobicContact CG1-CG1 4.36Å; I103-V229 HydrophobicContact CG1-CG2 3.69Å; F207-V229 PolarHBondContact O-N 2.79Å; D208-V229 HydrophobicContact CB-CG2 4.16Å; L209-V229 PolarHBondContact N-O 3.42Å; V229-L246 HydrophobicContact CG1-CD1 3.8Å
230W98.6Very high97.3Very high0 Ų028.7 Ų28.70%014%0.143CC..EExtended strand (participates in β ladder)trans-162.8152.5172.857.191.5000112.8M82 I86 I93 L209 I213 A228 A244 G245M82-W230 HydrophobicContact SD-CZ2 4.21Å; I86-W230 HydrophobicContact CD1-CH2 3.84Å; I86-W230 HydrophobicContact CD1-CZ3 4.32Å; I93-W230 HydrophobicContact CG2-CH2 4.08Å; I93-W230 HydrophobicContact CG2-CZ2 3.96Å; L209-W230 HydrophobicContact CB-CB 3.89Å; L209-W230 HydrophobicContact CD1-CD2 4.23Å; L209-W230 HydrophobicContact CD1-CE3 3.53Å; L209-W230 HydrophobicContact CD1-CZ3 3.97Å; L209-W230 HydrophobicContact CG-CE3 4.03Å; I213-W230 HydrophobicContact CB-CB 4.39Å; I213-W230 HydrophobicContact CB-CG 4.28Å; I213-W230 HydrophobicContact CG1-CG 4.34Å; I213-W230 HydrophobicContact CG2-CB 3.86Å; I213-W230 HydrophobicContact CG2-CG 3.97Å; A228-W230 HydrophobicContact CB-CE3 4.45Å; A228-W230 HydrophobicContact CB-CZ3 4.23Å; W230-A244 CarbonylContact O-C 3.41Å; W230-A244 VanDerWaalsContact O-CA 3.25Å; W230-A244 WeakPolarHBondContact O-CA 3.22Å; W230-A244 WeakPolarHBondContact O-CB 3.14Å; W230-G245 PolarHBondContact N-O 3.28Å; W230-G245 VanDerWaalsContact N-O 3.15Å; W230-G245 PolarHBondContact O-N 3.35Å
231C98.2Very high96.9Very high2 Ų232 Ų321%0.01418%0.177CC..  trans-82.7164.3165.869.50000111.1T99 C210 Y233 K234T99-C231 WeakPolarHBondContact OG1-CA 2.98Å; T99-C231 VanDerWaalsContact OG1-CB 3.32Å; T99-C231 WeakPolarHBondContact OG1-CB 3.36Å; T99-C231 PolarHBondContact OG1-N 2.83Å; T99-C231 VanDerWaalsContact OG1-N 3.1Å; C210-C231 PolarHBondContact SG-N 3.42Å; C231-Y233 HydrophobicContact CB-CD1 3.69Å; C231-Y233 HydrophobicContact CB-CE1 3.33Å; C231-Y233 HydrophobicContact CB-CG 4.46Å; C231-K234 WeakPolarHBondContact SG-CD 2.95Å
232T98.3Very high96.8Very high0 Ų026.5 Ų26.50%015%0.154CC..SBendtrans-117.2-0.8-17959.50000113.4M82 L236 G238 S242 T243 L299M82-T232 HydrophobicContact CE-CG2 3.36Å; T232-L236 HydrophobicContact CG2-CD1 4.2Å; T232-L236 CarbonylContact O-C 3.58Å; T232-L236 VanDerWaalsContact O-CB 3.29Å; T232-L236 WeakPolarHBondContact O-CB 3.37Å; T232-G238 VanDerWaalsContact O-CA 3.3Å; T232-G238 WeakPolarHBondContact O-CA 3.26Å; T232-G238 PolarHBondContact O-N 3.19Å; T232-S242 VanDerWaalsContact C-OG 3.3Å; T232-S242 WeakPolarHBondContact OG1-CB 3.25Å; T232-S242 PolarHBondContact OG1-OG 3.16Å; T232-T243 WeakPolarHBondContact CG2-O 3.38Å; T232-T243 PolarHBondContact OG1-O 3.42Å; T232-L299 HydrophobicContact CG2-CD1 4.22Å; T232-L299 HydrophobicContact CG2-CD2 3.77Å
233Y97.3Very high96.8Very high72 Ų7221.4 Ų21.428%0.28213%0.131SC..SBendtrans-92.2-8.2-175.160.1-103.6000114.7S41 L42 G43 C231 G239 S242S41-Y233 WeakPolarHBondContact O-CD2 3.19Å; S41-Y233 WeakPolarHBondContact O-CE2 3.32Å; L42-Y233 WeakPolarHBondContact CA-O 3.17Å; L42-Y233 HydrophobicContact CD1-CD2 4.42Å; G43-Y233 PolarHBondContact N-O 3.3Å; C231-Y233 HydrophobicContact CB-CD1 3.69Å; C231-Y233 HydrophobicContact CB-CE1 3.33Å; C231-Y233 HydrophobicContact CB-CG 4.46Å; Y233-G239 WeakPolarHBondContact CB-O 3.37Å; Y233-S242 WeakPolarHBondContact CB-OG 3.47Å; Y233-S242 PolarHBondContact N-OG 2.91Å
234K97.5Very high96.8Very high17 Ų1720.6 Ų20.67%0.07413%0.126CC..SBendtrans-82-119.8176.7-68.5176176.9177.70109.8G39 N40 S41 G43 C210 H211 C231 L236 N237G39-K234 CarbonylContact O-C 3.23Å; N40-K234 VanDerWaalsContact O-CD 3.27Å; N40-K234 WeakPolarHBondContact O-CD 3.31Å; N40-K234 WeakPolarHBondContact O-CG 3.48Å; S41-K234 VanDerWaalsContact O-CG 3.3Å; S41-K234 WeakPolarHBondContact O-CG 3.42Å; G43-K234 VanDerWaalsContact CA-O 3.24Å; G43-K234 WeakPolarHBondContact CA-O 3.45Å; G43-K234 PolarHBondContact N-O 2.77Å; C210-K234 HydrophobicContact CB-CD 4.38Å; C210-K234 VanDerWaalsContact O-CD 3.22Å; C210-K234 WeakPolarHBondContact O-CD 3Å; H211-K234 PolarHBondContact CD2-NZ 3.26Å; H211-K234 VanDerWaalsContact CD2-NZ 3.31Å; H211-K234 PolarHBondContact NE2-NZ 3.09Å; C231-K234 WeakPolarHBondContact SG-CD 2.95Å; K234-L236 PolarHBondContact O-N 2.82Å; K234-N237 PolarHBondContact O-N 3.18Å
235Y97.6Very high96.8Very high10 Ų1017.8 Ų17.84%0.03911%0.113CC..THydrogen-bonded Turntrans-54.9-30.1179.6-66.4-81.2000114G39 N40 H211 A215 N237 F306 G351 H352 I387G39-Y235 PolarHBondContact O-N 3.02Å; N40-Y235 HydrophobicContact CB-CE1 4.01Å; N40-Y235 HydrophobicContact CB-CE2 3.77Å; N40-Y235 WeakPolarHBondContact CB-OH 3.45Å; H211-Y235 WeakPolarHBondContact O-CE2 3.48Å; A215-Y235 HydrophobicContact CB-CD1 3.86Å; A215-Y235 HydrophobicContact CB-CD2 3.68Å; A215-Y235 HydrophobicContact CB-CE1 3.9Å; A215-Y235 HydrophobicContact CB-CE2 3.71Å; A215-Y235 HydrophobicContact CB-CG 3.75Å; Y235-N237 VanDerWaalsContact C-N 3.27Å; Y235-N237 PolarHBondContact O-N 3.48Å; Y235-N237 PolarHBondContact O-ND2 2.62Å; Y235-F306 WeakPolarHBondContact O-CZ 3.44Å; Y235-G351 WeakPolarHBondContact OH-CA 3.43Å; Y235-H352 PolarHBondContact OH-ND1 2.68Å; Y235-I387 HydrophobicContact CD1-CD1 3.69Å; Y235-I387 HydrophobicContact CE1-CD1 3.57Å
236L97.9Very high96.8Very high1 Ų117.8 Ų17.81%0.00511%0.113CC..THydrogen-bonded Turntrans-77.9-0.9177.9-67.5-173.7000114.8M82 L85 I213 T232 K234 G238 S302 L303 F306M82-L236 HydrophobicContact CE-CD1 3.79Å; L85-L236 HydrophobicContact CD1-CD1 4.09Å; L85-L236 HydrophobicContact CD1-CD2 3.7Å; I213-L236 HydrophobicContact CB-CD1 4.5Å; I213-L236 HydrophobicContact CG1-CD1 3.69Å; I213-L236 HydrophobicContact CG1-CD2 4.47Å; I213-L236 HydrophobicContact CG1-CG 4.23Å; I213-L236 HydrophobicContact CG2-CD1 4.02Å; I213-L236 HydrophobicContact CG2-CG 4.22Å; T232-L236 HydrophobicContact CG2-CD1 4.2Å; T232-L236 CarbonylContact O-C 3.58Å; T232-L236 VanDerWaalsContact O-CB 3.29Å; T232-L236 WeakPolarHBondContact O-CB 3.37Å; K234-L236 PolarHBondContact O-N 2.82Å; L236-G238 PolarHBondContact O-N 2.9Å; L236-S302 VanDerWaalsContact O-CB 3.29Å; L236-S302 WeakPolarHBondContact O-CB 3.32Å; L236-S302 PolarHBondContact O-OG 3.44Å; L236-L303 HydrophobicContact CD1-CD2 4.42Å; L236-L303 HydrophobicContact CD2-CD2 4.36Å; L236-F306 HydrophobicContact CD2-CD1 4.08Å; L236-F306 HydrophobicContact CD2-CD2 4.27Å; L236-F306 HydrophobicContact CD2-CE1 3.9Å; L236-F306 HydrophobicContact CD2-CE2 4.1Å; L236-F306 HydrophobicContact CD2-CG 4.29Å; L236-F306 HydrophobicContact CD2-CZ 3.94Å
237N97.3Very high96.8Very high1 Ų117.6 Ų17.61%0.00511%0.112CC..  trans5331.1172.4-50-50.7000114.9F28 G43 M44 K234 Y235 G239F28-N237 HydrophobicContact CE1-CB 4.26Å; F28-N237 WeakPolarHBondContact CE1-ND2 3.29Å; G43-N237 WeakPolarHBondContact CA-OD1 3.32Å; M44-N237 PolarHBondContact N-OD1 3.02Å; M44-N237 WeakPolarHBondContact O-CB 3.45Å; K234-N237 PolarHBondContact O-N 3.18Å; Y235-N237 VanDerWaalsContact C-N 3.27Å; Y235-N237 PolarHBondContact O-N 3.48Å; Y235-N237 PolarHBondContact O-ND2 2.62Å; N237-G239 PolarHBondContact O-N 3.36Å
238G95.8Very high96.8Very high6 Ų617.6 Ų17.66%0.06211%0.112CC..  trans-72.1-7.6-175.800000115.2T232 L236 S242T232-G238 VanDerWaalsContact O-CA 3.3Å; T232-G238 WeakPolarHBondContact O-CA 3.26Å; T232-G238 PolarHBondContact O-N 3.19Å; L236-G238 PolarHBondContact O-N 2.9Å; G238-S242 VanDerWaalsContact O-CB 3.26Å; G238-S242 WeakPolarHBondContact O-CB 3.46Å
239G91.7Very high96.8Very high29 Ų2917.6 Ų17.630%0.29911%0.112SC..  trans93.9164-177.800000113.7Y233 N237 G241 S242Y233-G239 WeakPolarHBondContact CB-O 3.37Å; N237-G239 PolarHBondContact O-N 3.36Å; G239-G241 PolarHBondContact O-N 3.22Å; G239-S242 VanDerWaalsContact O-CB 3.23Å; G239-S242 WeakPolarHBondContact O-CB 3.35Å; G239-S242 PolarHBondContact O-N 2.92Å; G239-S242 VanDerWaalsContact O-N 3.09Å; G239-S242 PolarHBondContact O-OG 3.41Å
240L88.9Confident96.7Very high153 Ų15321.5 Ų21.580%0.80113%0.13SC*.THydrogen-bonded Turntrans-53.9123.7-173-64.8122000112.6L42 S242L42-L240 HydrophobicContact CD1-CD2 4.46Å; L42-L240 HydrophobicContact CD1-CG 4.16Å; L42-L240 HydrophobicContact CD2-CD2 3.77Å; L42-L240 HydrophobicContact CD2-CG 4.09Å; L240-S242 PolarHBondContact O-N 2.84Å
241G89.4Confident96.7Very high69 Ų6925.9 Ų25.971%0.71115%0.149SC*.THydrogen-bonded Turntrans62.323.6177.300000114.2G239G239-G241 PolarHBondContact O-N 3.22Å
242S96.1Very high96.7Very high5 Ų526.5 Ų26.54%0.03515%0.152CC..PPolyproline II helixtrans-59.6151.8-176.662.60000113T232 Y233 G238 G239 L240 S295T232-S242 VanDerWaalsContact C-OG 3.3Å; T232-S242 WeakPolarHBondContact OG1-CB 3.25Å; T232-S242 PolarHBondContact OG1-OG 3.16Å; Y233-S242 WeakPolarHBondContact CB-OG 3.47Å; Y233-S242 PolarHBondContact N-OG 2.91Å; G238-S242 VanDerWaalsContact O-CB 3.26Å; G238-S242 WeakPolarHBondContact O-CB 3.46Å; G239-S242 VanDerWaalsContact O-CB 3.23Å; G239-S242 WeakPolarHBondContact O-CB 3.35Å; G239-S242 PolarHBondContact O-N 2.92Å; G239-S242 VanDerWaalsContact O-N 3.09Å; G239-S242 PolarHBondContact O-OG 3.41Å; L240-S242 PolarHBondContact O-N 2.84Å; S242-S295 WeakPolarHBondContact CA-OG 3.44Å; S242-S295 WeakPolarHBondContact CB-OG 3.48Å
243T97.5Very high96.6Very high4 Ų428.9 Ų28.93%0.02516%0.163CC..PPolyproline II helixtrans-57.4138.2-175.7-170.80000112.3V95 T96 G97 T232 T292 S295 M296V95-T243 HydrophobicContact CG1-CG2 3.47Å; V95-T243 VanDerWaalsContact CG1-CG2 3.47Å; T96-T243 VanDerWaalsContact C-OG1 3.31Å; T96-T243 WeakPolarHBondContact CA-OG1 3.25Å; G97-T243 VanDerWaalsContact O-CA 3.32Å; G97-T243 WeakPolarHBondContact O-CA 3.5Å; G97-T243 PolarHBondContact O-OG1 3.44Å; T232-T243 WeakPolarHBondContact CG2-O 3.38Å; T232-T243 PolarHBondContact OG1-O 3.42Å; T243-T292 VanDerWaalsContact CB-OG1 3.31Å; T243-T292 WeakPolarHBondContact CB-OG1 3.33Å; T243-S295 PolarHBondContact N-OG 2.88Å; T243-M296 HydrophobicContact CG2-CG 3.8Å
244A98.2Very high96.6Very high1 Ų131.9 Ų31.91%0.00818%0.184CC..PPolyproline II helixtrans-83.2161.8-174.700000112.5V95 T96 G97 T99 N102 W230V95-A244 CarbonylContact C-O 3.58Å; V95-A244 WeakPolarHBondContact CA-O 3.41Å; T96-A244 PolarHBondContact N-O 3.18Å; T96-A244 VanDerWaalsContact O-O 3.08Å; G97-A244 PolarHBondContact O-N 2.91Å; T99-A244 VanDerWaalsContact N-CB 3.29Å; N102-A244 WeakPolarHBondContact ND2-CB 3.19Å; W230-A244 CarbonylContact O-C 3.41Å; W230-A244 VanDerWaalsContact O-CA 3.25Å; W230-A244 WeakPolarHBondContact O-CA 3.22Å; W230-A244 WeakPolarHBondContact O-CB 3.14Å
245G98.3Very high96.5Very high0 Ų034.7 Ų34.70%020%0.196CC..EExtended strand (participates in β ladder)trans-96151.4166.400000111.8T94 N102 W230T94-G245 WeakPolarHBondContact O-CA 3.21Å; N102-G245 PolarHBondContact ND2-O 3.18Å; W230-G245 PolarHBondContact N-O 3.28Å; W230-G245 VanDerWaalsContact N-O 3.15Å; W230-G245 PolarHBondContact O-N 3.35Å
246L98.6Very high96.3Very high0 Ų042.3 Ų42.30%023%0.229CC..EExtended strand (participates in β ladder)trans-133.5122169.4171.365.9000107.6I93 T94 N102 A106 A228 V229 I248 W286I93-L246 WeakPolarHBondContact CA-O 3.3Å; T94-L246 HydrophobicContact CG2-CB 3.81Å; T94-L246 HydrophobicContact CG2-CD2 4.01Å; T94-L246 HydrophobicContact CG2-CG 4.18Å; T94-L246 PolarHBondContact N-O 3.09Å; T94-L246 PolarHBondContact O-N 3.07Å; N102-L246 HydrophobicContact CB-CB 4.25Å; N102-L246 HydrophobicContact CB-CD1 4.43Å; A106-L246 HydrophobicContact CB-CD1 4.29Å; A228-L246 CarbonylContact O-C 3.47Å; A228-L246 WeakPolarHBondContact O-CA 3.42Å; V229-L246 HydrophobicContact CG1-CD1 3.8Å; L246-I248 HydrophobicContact CD1-CD1 4.02Å; L246-I248 HydrophobicContact CD2-CD1 4.34Å; L246-I248 HydrophobicContact CD2-CG1 4.37Å; L246-I248 HydrophobicContact CG-CD1 4.18Å; L246-I248 HydrophobicContact CG-CG1 4.18Å; L246-W286 HydrophobicContact CD2-CB 3.76Å; L246-W286 HydrophobicContact CD2-CG 4.23Å
247Y98.8Very high96.2Very high0 Ų042.7 Ų42.70%023%0.232CC..EExtended strand (participates in β ladder)trans-97.4133.3169.2168.5-93.3000109.6I86 A88 E92 I93 F220 P225 F227 A228 N249I86-Y247 HydrophobicContact CD1-CD2 4.04Å; I86-Y247 HydrophobicContact CD1-CG 4.48Å; A88-Y247 HydrophobicContact CB-CD2 4.1Å; A88-Y247 HydrophobicContact CB-CE2 3.76Å; E92-Y247 HydrophobicContact CB-CD2 3.7Å; E92-Y247 HydrophobicContact CB-CE2 3.44Å; E92-Y247 VanDerWaalsContact CB-CE2 3.44Å; E92-Y247 HydrophobicContact CG-CE2 4.21Å; E92-Y247 CarbonylContact O-C 3.19Å; E92-Y247 WeakPolarHBondContact O-CA 3.4Å; E92-Y247 VanDerWaalsContact O-CD2 3.29Å; E92-Y247 WeakPolarHBondContact O-CD2 3.41Å; I93-Y247 HydrophobicContact CG1-CD2 4.4Å; F220-Y247 HydrophobicContact CB-CE2 4.42Å; F220-Y247 AromaticContact CD2-CD1 3.82Å; F220-Y247 HydrophobicContact CD2-CD1 3.82Å; F220-Y247 AromaticContact CD2-CD2 3.8Å; F220-Y247 HydrophobicContact CD2-CD2 3.8Å; F220-Y247 AromaticContact CD2-CE1 3.87Å; F220-Y247 HydrophobicContact CD2-CE1 3.87Å; F220-Y247 AromaticContact CD2-CE2 3.81Å; F220-Y247 HydrophobicContact CD2-CE2 3.81Å; F220-Y247 AromaticContact CD2-CG 3.8Å; F220-Y247 HydrophobicContact CD2-CG 3.8Å; F220-Y247 AromaticContact CD2-CZ 3.85Å; F220-Y247 AromaticContact CE2-CD1 3.83Å; F220-Y247 HydrophobicContact CE2-CD1 3.83Å; F220-Y247 HydrophobicContact CE2-CD2 4.29Å; F220-Y247 HydrophobicContact CE2-CE1 4.26Å; F220-Y247 AromaticContact CE2-CG 3.85Å; F220-Y247 HydrophobicContact CE2-CG 3.85Å; P225-Y247 HydrophobicContact CG-CD1 4.32Å; P225-Y247 HydrophobicContact CG-CE1 3.87Å; P225-Y247 WeakPolarHBondContact O-CE1 3.44Å; F227-Y247 CarbonylContact C-O 3.53Å; F227-Y247 WeakPolarHBondContact CA-O 3.49Å; F227-Y247 WeakPolarHBondContact CB-O 3.43Å; A228-Y247 HydrophobicContact CB-CD1 4.33Å; A228-Y247 PolarHBondContact N-O 3.05Å; A228-Y247 PolarHBondContact O-N 3.1Å; Y247-N249 HydrophobicContact CE1-CB 4.01Å; Y247-N249 PolarHBondContact OH-ND2 2.9Å
248I98.7Very high96.2Very high0 Ų044.4 Ų44.40%025%0.25CC..EExtended strand (participates in β ladder)trans-126.1121.9169-58.4-66.3000106.5E92 F110 F227 L246 Q250 H252 F253 A283 W286E92-I248 WeakPolarHBondContact CA-O 3.4Å; E92-I248 WeakPolarHBondContact CB-O 3.11Å; E92-I248 PolarHBondContact O-N 3.18Å; F110-I248 HydrophobicContact CE2-CD1 3.75Å; F110-I248 HydrophobicContact CZ-CD1 4.16Å; F110-I248 HydrophobicContact CZ-CG2 4.33Å; F227-I248 HydrophobicContact CB-CD1 3.99Å; L246-I248 HydrophobicContact CD1-CD1 4.02Å; L246-I248 HydrophobicContact CD2-CD1 4.34Å; L246-I248 HydrophobicContact CD2-CG1 4.37Å; L246-I248 HydrophobicContact CG-CD1 4.18Å; L246-I248 HydrophobicContact CG-CG1 4.18Å; I248-Q250 PolarHBondContact O-N 2.95Å; I248-H252 HydrophobicContact CG2-CB 4.03Å; I248-F253 HydrophobicContact CB-CE1 4.47Å; I248-F253 HydrophobicContact CG2-CD1 4.32Å; I248-F253 HydrophobicContact CG2-CE1 4.37Å; I248-F253 WeakPolarHBondContact O-CE1 3.34Å; I248-A283 HydrophobicContact CB-CB 4.22Å; I248-A283 HydrophobicContact CG1-CB 4.46Å; I248-W286 HydrophobicContact CG1-CD2 4.13Å; I248-W286 HydrophobicContact CG1-CE3 4.34Å; I248-W286 HydrophobicContact CG1-CG 4.4Å; I248-W286 HydrophobicContact CG2-CH2 4.3Å; I248-W286 HydrophobicContact CG2-CZ2 4.49Å; I248-W286 HydrophobicContact CG2-CZ3 4.41Å
249N98.7Very high96.2Very high0 Ų047.6 Ų47.60%027%0.265CS..  trans-59.1135.9177.9-169.2-61.2000110.3Q224 P225 D226 Y247 K251 H252Q224-N249 PolarHBondContact OE1-ND2 2.99Å; P225-N249 VanDerWaalsContact O-CB 3.3Å; P225-N249 WeakPolarHBondContact O-CB 3.42Å; P225-N249 PolarHBondContact O-ND2 2.96Å; P225-N249 VanDerWaalsContact O-ND2 3.11Å; D226-N249 WeakPolarHBondContact O-CB 3.4Å; D226-N249 PolarHBondContact O-N 3.1Å; Y247-N249 HydrophobicContact CE1-CB 4.01Å; Y247-N249 PolarHBondContact OH-ND2 2.9Å; N249-K251 HydrophobicContact CB-CG 4.19Å; N249-K251 PolarHBondContact O-N 3.41Å; N249-K251 VanDerWaalsContact OD1-CG 3.29Å; N249-K251 WeakPolarHBondContact OD1-CG 3.48Å; N249-K251 PolarHBondContact OD1-N 3.21Å; N249-H252 PolarHBondContact O-N 3.46Å
250Q98.1Very high96.4Very high81 Ų8148.9 Ų48.938%0.37927%0.273SS..G310 helixtrans-52.5-25.2-178.764.9178.77.100114.2E92 I248 H252 F253E92-Q250 HydrophobicContact CG-CB 3.97Å; E92-Q250 WeakPolarHBondContact OE1-CB 3.38Å; E92-Q250 WeakPolarHBondContact OE1-CG 3.2Å; E92-Q250 PolarHBondContact OE1-N 3.42Å; I248-Q250 PolarHBondContact O-N 2.95Å; Q250-H252 PolarHBondContact O-N 3.27Å; Q250-H252 VanDerWaalsContact O-N 3.16Å; Q250-F253 HydrophobicContact CB-CD2 4.05Å; Q250-F253 HydrophobicContact CB-CE1 4.49Å; Q250-F253 HydrophobicContact CB-CE2 3.65Å; Q250-F253 HydrophobicContact CB-CZ 3.89Å; Q250-F253 WeakPolarHBondContact O-CG 3.38Å; Q250-F253 PolarHBondContact O-N 3.18Å
251K97.5Very high96.7Very high92 Ų9242.2 Ų42.240%0.424%0.241SC..G310 helixtrans-64.8-13.5177.178.3-169.8-178.6-178.20113.8H199 D226 N249H199-K251 PolarHBondContact CE1-NZ 2.88Å; H199-K251 PolarHBondContact NE2-NZ 2.92Å; D226-K251 WeakPolarHBondContact OD1-CE 3.3Å; D226-K251 IonicContact OD1-NZ 3.62Å; D226-K251 PolarHBondContact OD1-NZ 3.49Å; N249-K251 HydrophobicContact CB-CG 4.19Å; N249-K251 PolarHBondContact O-N 3.41Å; N249-K251 VanDerWaalsContact OD1-CG 3.29Å; N249-K251 WeakPolarHBondContact OD1-CG 3.48Å; N249-K251 PolarHBondContact OD1-N 3.21Å
252H98.1Very high96.9Very high16 Ų1644.6 Ų44.67%0.07423%0.229CC..G310 helixtrans-1107.6-178.8-62.1-57.2000113.7F110 D226 I248 N249 Q250 D254 K255F110-H252 HydrophobicContact CE1-CB 4.01Å; F110-H252 AromaticContact CE1-CD2 3.56Å; F110-H252 AromaticContact CE1-CG 3.59Å; F110-H252 AromaticContact CE1-ND1 3.9Å; F110-H252 AromaticContact CE1-NE2 3.84Å; F110-H252 HydrophobicContact CZ-CB 4.11Å; F110-H252 AromaticContact CZ-CD2 3.8Å; D226-H252 WeakPolarHBondContact CB-NE2 3.3Å; D226-H252 IonicContact OD1-CD2 2.87Å; D226-H252 IonicContact OD1-CE1 2.63Å; D226-H252 IonicContact OD1-NE2 2.79Å; D226-H252 PolarHBondContact OD1-NE2 3.48Å; I248-H252 HydrophobicContact CG2-CB 4.03Å; N249-H252 PolarHBondContact O-N 3.46Å; Q250-H252 PolarHBondContact O-N 3.27Å; Q250-H252 VanDerWaalsContact O-N 3.16Å; H252-D254 PolarHBondContact O-N 3.11Å; H252-D254 VanDerWaalsContact O-N 3.11Å; H252-K255 HydrophobicContact CB-CD 4.13Å; H252-K255 HydrophobicContact CB-CG 4.37Å; H252-K255 WeakPolarHBondContact ND1-CE 3.42Å; H252-K255 WeakPolarHBondContact O-CB 3.39Å; H252-K255 PolarHBondContact O-N 2.9Å
253F97.5Very high96.9Very high49 Ų4944.6 Ų44.622%0.21523%0.228CC..THydrogen-bonded Turntrans-65.1-11.2178.4-68.1-12.2000113.9Q91 E92 I248 Q250 P281 D282 A283Q91-F253 HydrophobicContact CB-CE2 4.33Å; Q91-F253 HydrophobicContact CB-CZ 4.41Å; Q91-F253 WeakPolarHBondContact O-CZ 3.44Å; E92-F253 HydrophobicContact CB-CZ 4.37Å; E92-F253 HydrophobicContact CG-CZ 3.8Å; I248-F253 HydrophobicContact CB-CE1 4.47Å; I248-F253 HydrophobicContact CG2-CD1 4.32Å; I248-F253 HydrophobicContact CG2-CE1 4.37Å; I248-F253 WeakPolarHBondContact O-CE1 3.34Å; Q250-F253 HydrophobicContact CB-CD2 4.05Å; Q250-F253 HydrophobicContact CB-CE1 4.49Å; Q250-F253 HydrophobicContact CB-CE2 3.65Å; Q250-F253 HydrophobicContact CB-CZ 3.89Å; Q250-F253 WeakPolarHBondContact O-CG 3.38Å; Q250-F253 PolarHBondContact O-N 3.18Å; F253-P281 WeakPolarHBondContact CD2-O 3.47Å; F253-D282 HydrophobicContact CD2-CB 4.38Å; F253-D282 HydrophobicContact CE2-CB 3.99Å; F253-D282 HydrophobicContact CZ-CB 4.13Å; F253-A283 HydrophobicContact CE1-CB 4.27Å
254D95.8Very high96.8Very high135 Ų13544.4 Ų44.472%0.72223%0.227SC*.THydrogen-bonded Turntrans-81.6-14.4171.469.7-36.9000113.2H252H252-D254 PolarHBondContact O-N 3.11Å; H252-D254 VanDerWaalsContact O-N 3.11Å
255K95.3Very high96.7Very high76 Ų7645.2 Ų45.233%0.3323%0.231SC..SBendtrans-76.2147.3176.8-62.9-171.1-177.6-63.90111T109 F110 H252 W286T109-K255 HydrophobicContact CG2-CB 4.48Å; F110-K255 HydrophobicContact CD1-CD 4.19Å; F110-K255 HydrophobicContact CE1-CD 3.86Å; H252-K255 HydrophobicContact CB-CD 4.13Å; H252-K255 HydrophobicContact CB-CG 4.37Å; H252-K255 WeakPolarHBondContact ND1-CE 3.42Å; H252-K255 WeakPolarHBondContact O-CB 3.39Å; H252-K255 PolarHBondContact O-N 2.9Å; K255-W286 HydrophobicContact CB-CH2 4.48Å; K255-W286 HydrophobicContact CB-CZ2 4.31Å; K255-W286 VanDerWaalsContact O-CH2 3.29Å; K255-W286 WeakPolarHBondContact O-CH2 3.32Å
256K93.7Very high96.6Very high170 Ų17048.8 Ų48.874%0.73925%0.245SC*.PPolyproline II helixtrans-81.5136171.1-67.9-175.1178.9-177.80109.9G258K256-G258 PolarHBondContact O-N 2.87Å
257P96.9Very high96.4Very high10 Ų1050.2 Ų50.27%0.06525%0.253CS..PPolyproline II helixtrans-54128.7170.1-22.528.9000111.6L259 F277 G285 W286P257-L259 VanDerWaalsContact C-N 3.25Å; P257-L259 PolarHBondContact O-N 3.44Å; P257-F277 HydrophobicContact CG-CE1 4.17Å; P257-F277 HydrophobicContact CG-CZ 4.37Å; P257-G285 WeakPolarHBondContact CG-O 3.5Å; P257-W286 HydrophobicContact CB-CD2 4.17Å; P257-W286 HydrophobicContact CB-CG 4.04Å; P257-W286 HydrophobicContact CG-CD2 3.9Å; P257-W286 HydrophobicContact CG-CE3 4.22Å; P257-W286 HydrophobicContact CG-CG 4.19Å; P257-W286 HydrophobicContact CG-CZ2 4.39Å
258G95.8Very high96.1Very high37 Ų3754.9 Ų54.938%0.38128%0.277SS..SBendtrans-65.7-29.8178.300000113.2T109 K256T109-G258 PolarHBondContact OG1-N 3.3Å; K256-G258 PolarHBondContact O-N 2.87Å
259L96.3Very high95.9Very high72 Ų7256.1 Ų56.138%0.37729%0.285SS..SBendtrans-118.286.7170.2-58.5-179.7000108.2H104 A108 P257 I288H104-L259 HydrophobicContact CB-CD1 4.33Å; A108-L259 HydrophobicContact CB-CD2 4.19Å; A108-L259 HydrophobicContact CB-CG 3.87Å; P257-L259 VanDerWaalsContact C-N 3.25Å; P257-L259 PolarHBondContact O-N 3.44Å; L259-I288 HydrophobicContact CB-CD1 3.8Å; L259-I288 HydrophobicContact CB-CG1 4.41Å; L259-I288 HydrophobicContact CD1-CD1 4.22Å
260A95.8Very high95.6Very high56 Ų5656.5 Ų56.546%0.46329%0.287SS..  trans-76.2145177.900000111.3F277A260-F277 HydrophobicContact CB-CD1 3.92Å; A260-F277 HydrophobicContact CB-CE1 3.68Å; A260-F277 HydrophobicContact CB-CE2 4.37Å; A260-F277 HydrophobicContact CB-CG 4.36Å; A260-F277 HydrophobicContact CB-CZ 3.94Å
261G94.8Very high95.4Very high14 Ų1457.7 Ų57.714%0.14429%0.291CS..  trans-152.3168.4171.600000111.6F263 G264 F277 I288G261-F263 VanDerWaalsContact C-N 3.31Å; G261-F263 PolarHBondContact O-N 3.41Å; G261-G264 PolarHBondContact O-N 3.33Å; G261-F277 VanDerWaalsContact O-CE2 3.28Å; G261-F277 WeakPolarHBondContact O-CE2 3.39Å; G261-I288 CarbonylContact C-O 3.59Å; G261-I288 VanDerWaalsContact C-O 3.26Å; G261-I288 WeakPolarHBondContact CA-O 3.49Å
262W94.6Very high95.3Very high118 Ų11858.3 Ų58.345%0.44730%0.295SS..G310 helixtrans-65.3-29.8-161.975.7-52.5000114.8G264 N265 L273 I288 S290W262-G264 PolarHBondContact O-N 3.24Å; W262-N265 WeakPolarHBondContact O-CB 3.41Å; W262-N265 PolarHBondContact O-N 3.45Å; W262-N265 PolarHBondContact O-ND2 3.23Å; W262-L273 HydrophobicContact CE3-CD2 4.25Å; W262-L273 HydrophobicContact CZ3-CD2 4.1Å; W262-I288 PolarHBondContact N-O 3.44Å; W262-S290 WeakPolarHBondContact CZ2-OG 3.5Å
263F95.3Very high95Very high5 Ų563 Ų632%0.02232%0.32CS..G310 helixtrans-75.2-11.1174.5-98.1-100.4000113.8W68 G261 Q287 G289 S290 P291W68-F263 HydrophobicContact CH2-CZ 4.46Å; W68-F263 HydrophobicContact CZ3-CE1 4.38Å; W68-F263 AromaticContact CZ3-CZ 3.98Å; W68-F263 HydrophobicContact CZ3-CZ 3.98Å; G261-F263 VanDerWaalsContact C-N 3.31Å; G261-F263 PolarHBondContact O-N 3.41Å; F263-Q287 HydrophobicContact CB-CB 4.06Å; F263-G289 WeakPolarHBondContact CB-O 3.23Å; F263-S290 VanDerWaalsContact CD2-CA 3.42Å; F263-S290 VanDerWaalsContact CE2-CA 3.44Å; F263-S290 VanDerWaalsContact CE2-CB 3.48Å; F263-S290 WeakPolarHBondContact CE2-OG 3.43Å; F263-P291 HydrophobicContact CD1-CG 4.38Å; F263-P291 HydrophobicContact CE1-CG 3.93Å
264G96.6Very high94.8Very high0 Ų067 Ų670%034%0.337CS..G310 helixtrans-77.6-8.1168.900000113.1G261 W262 P279 Q280 G285 Q287G261-G264 PolarHBondContact O-N 3.33Å; W262-G264 PolarHBondContact O-N 3.24Å; G264-P279 CarbonylContact O-C 3.2Å; G264-P279 VanDerWaalsContact O-CA 3.3Å; G264-P279 WeakPolarHBondContact O-CA 2.87Å; G264-Q280 PolarHBondContact O-N 2.91Å; G264-G285 WeakPolarHBondContact CA-O 2.93Å; G264-G285 WeakPolarHBondContact O-CA 3.1Å; G264-Q287 WeakPolarHBondContact CA-O 3.26Å; G264-Q287 PolarHBondContact N-O 3.37Å
265N96.2Very high94.8Very high19 Ų1970 Ų7010%0.10235%0.347CS..BIsolated β-bridgetrans-69.2158.5175.2-76.6-77.5000111.4W262 N267 Q270 F277 D278W262-N265 WeakPolarHBondContact O-CB 3.41Å; W262-N265 PolarHBondContact O-N 3.45Å; W262-N265 PolarHBondContact O-ND2 3.23Å; N265-N267 PolarHBondContact O-N 3.01Å; N265-Q270 HydrophobicContact CB-CB 3.83Å; N265-F277 VanDerWaalsContact OD1-CD2 3.3Å; N265-F277 WeakPolarHBondContact OD1-CD2 3.34Å; N265-D278 CarbonylContact C-O 3.5Å; N265-D278 WeakPolarHBondContact CA-O 3.23Å; N265-D278 PolarHBondContact OD1-N 2.94Å; N265-D278 PolarHBondContact OD1-O 3.2Å
266R95.7Very high94.7Very high75 Ų7574.2 Ų74.228%0.28337%0.368SS..  trans-55.4139.1172.7-61.9175.556.5862.8112.1D268 T269 Q270 D278 P279R266-D268 WeakPolarHBondContact CB-OD1 3.22Å; R266-D268 IonicContact CZ-OD1 3.65Å; R266-D268 IonicContact CZ-OD2 2.88Å; R266-D268 IonicContact NE-OD1 3.35Å; R266-D268 PolarHBondContact NE-OD1 3.26Å; R266-D268 IonicContact NE-OD2 3.67Å; R266-D268 IonicContact NH2-OD1 3.19Å; R266-D268 IonicContact NH2-OD2 3.4Å; R266-D268 PolarHBondContact NH2-OD2 3.05Å; R266-D268 PolarHBondContact O-N 3.43Å; R266-T269 PolarHBondContact O-N 3.02Å; R266-T269 VanDerWaalsContact O-N 3.11Å; R266-Q270 WeakPolarHBondContact O-CB 3.32Å; R266-Q270 PolarHBondContact O-N 3.43Å; R266-D278 VanDerWaalsContact CD-OD2 3.28Å; R266-D278 WeakPolarHBondContact CD-OD2 3.3Å; R266-D278 PolarHBondContact N-O 2.87Å; R266-P279 WeakPolarHBondContact CG-O 2.96Å
267N93.8Very high94.8Very high30 Ų3069.2 Ų69.216%0.1635%0.346CS..THydrogen-bonded Turntrans-59-34.7-176.9-70.1-25.3000113.9Y72 I73 E76 N265 Q270 Q280Y72-N267 HydrophobicContact CE2-CB 4.08Å; I73-N267 HydrophobicContact CG2-CB 4.33Å; I73-N267 WeakPolarHBondContact CG2-ND2 3.25Å; E76-N267 PolarHBondContact OE1-ND2 3.45Å; N265-N267 PolarHBondContact O-N 3.01Å; N267-Q270 PolarHBondContact OD1-NE2 2.88Å; N267-Q280 PolarHBondContact ND2-NE2 2.84Å
268D93.1Very high94.6Very high98 Ų9872.1 Ų72.152%0.52436%0.361SS..THydrogen-bonded Turntrans-76.2-18.5-178.356.7-4.7000113.8R266 Q272R266-D268 WeakPolarHBondContact CB-OD1 3.22Å; R266-D268 IonicContact CZ-OD1 3.65Å; R266-D268 IonicContact CZ-OD2 2.88Å; R266-D268 IonicContact NE-OD1 3.35Å; R266-D268 PolarHBondContact NE-OD1 3.26Å; R266-D268 IonicContact NE-OD2 3.67Å; R266-D268 IonicContact NH2-OD1 3.19Å; R266-D268 IonicContact NH2-OD2 3.4Å; R266-D268 PolarHBondContact NH2-OD2 3.05Å; R266-D268 PolarHBondContact O-N 3.43Å; D268-Q272 PolarHBondContact O-NE2 3.21Å
269T93.5Very high94.6Very high26 Ų2672.3 Ų72.316%0.1636%0.355CS..THydrogen-bonded Turntrans-119.1-15.8-177.464.90000114.7R266 F271 Q272R266-T269 PolarHBondContact O-N 3.02Å; R266-T269 VanDerWaalsContact O-N 3.11Å; T269-F271 VanDerWaalsContact C-N 3.31Å; T269-F271 PolarHBondContact O-N 2.95Å; T269-Q272 WeakPolarHBondContact O-CB 3.43Å; T269-Q272 WeakPolarHBondContact O-CG 3.37Å; T269-Q272 PolarHBondContact O-N 3.36Å
270Q93.3Very high94.6Very high7 Ų769.9 Ų69.93%0.03334%0.342CS..G310 helixtrans-56.9-39-17275-174.1-5300114.1N265 R266 N267 Q272 L273N265-Q270 HydrophobicContact CB-CB 3.83Å; R266-Q270 WeakPolarHBondContact O-CB 3.32Å; R266-Q270 PolarHBondContact O-N 3.43Å; N267-Q270 PolarHBondContact OD1-NE2 2.88Å; Q270-Q272 PolarHBondContact O-N 3Å; Q270-L273 PolarHBondContact O-N 3.25Å; Q270-L273 VanDerWaalsContact O-N 3.17Å
271F93.6Very high94.6Very high107 Ų10770.8 Ų70.847%0.46934%0.343SS..G310 helixtrans-79.90.4-179.9-65.3-70.8000113.8Y72 T269Y72-F271 AromaticContact CD1-CE2 3.94Å; Y72-F271 HydrophobicContact CD1-CE2 3.94Å; Y72-F271 HydrophobicContact CD1-CZ 4.2Å; Y72-F271 AromaticContact CD2-CE2 3.73Å; Y72-F271 HydrophobicContact CD2-CE2 3.73Å; Y72-F271 HydrophobicContact CD2-CZ 4.16Å; Y72-F271 HydrophobicContact CE1-CE2 4.1Å; Y72-F271 AromaticContact CE2-CE2 3.86Å; Y72-F271 HydrophobicContact CE2-CE2 3.86Å; Y72-F271 AromaticContact CG-CE2 3.72Å; Y72-F271 HydrophobicContact CG-CE2 3.72Å; Y72-F271 AromaticContact CG-CZ 3.83Å; Y72-F271 HydrophobicContact CG-CZ 3.83Å; T269-F271 VanDerWaalsContact C-N 3.31Å; T269-F271 PolarHBondContact O-N 2.95Å
272Q94.8Very high94.7Very high104 Ų10471.1 Ų71.149%0.48634%0.342SS..G310 helixtrans-77.8-10.4166.8-54.8176.217.600111.5D268 T269 Q270 K274D268-Q272 PolarHBondContact O-NE2 3.21Å; T269-Q272 WeakPolarHBondContact O-CB 3.43Å; T269-Q272 WeakPolarHBondContact O-CG 3.37Å; T269-Q272 PolarHBondContact O-N 3.36Å; Q270-Q272 PolarHBondContact O-N 3Å; Q272-K274 HydrophobicContact CB-CG 4.23Å; Q272-K274 PolarHBondContact O-N 3.1Å; Q272-K274 VanDerWaalsContact O-N 3.13Å
273L92.7Very high94.9Very high116 Ų11665.5 Ų65.561%0.60732%0.32SS*.  trans52.436.1174.6-54.8178000113.5W262 Q270W262-L273 HydrophobicContact CE3-CD2 4.25Å; W262-L273 HydrophobicContact CZ3-CD2 4.1Å; Q270-L273 PolarHBondContact O-N 3.25Å; Q270-L273 VanDerWaalsContact O-N 3.17Å
274K94Very high94.9Very high131 Ų13165.6 Ų65.657%0.5732%0.322SS*.  trans-67.4143.8175.2-66.6176.7179.8164.10109.6Q272 Q276Q272-K274 HydrophobicContact CB-CG 4.23Å; Q272-K274 PolarHBondContact O-N 3.1Å; Q272-K274 VanDerWaalsContact O-N 3.13Å; K274-Q276 VanDerWaalsContact C-N 3.26Å; K274-Q276 PolarHBondContact O-N 3.37Å
275H94.4Very high95Very high200 Ų20065.6 Ų65.693%0.92632%0.322SS*.SBendtrans-75.2-16176.2-66.6179.3000113.4
276Q94.5Very high95Very high164 Ų16464.8 Ų64.877%0.76632%0.317SS*.SBendtrans-83.2116.6174.7-176.2173.65.800109.3K274 D278K274-Q276 VanDerWaalsContact C-N 3.26Å; K274-Q276 PolarHBondContact O-N 3.37Å; Q276-D278 PolarHBondContact O-N 3.13Å
277F94.5Very high95.1Very high65 Ų6561.9 Ų61.929%0.28531%0.307SS..  trans-67.7125.6175.5-174.5-119.7000110.7P257 A260 G261 N265 P279P257-F277 HydrophobicContact CG-CE1 4.17Å; P257-F277 HydrophobicContact CG-CZ 4.37Å; A260-F277 HydrophobicContact CB-CD1 3.92Å; A260-F277 HydrophobicContact CB-CE1 3.68Å; A260-F277 HydrophobicContact CB-CE2 4.37Å; A260-F277 HydrophobicContact CB-CG 4.36Å; A260-F277 HydrophobicContact CB-CZ 3.94Å; G261-F277 VanDerWaalsContact O-CE2 3.28Å; G261-F277 WeakPolarHBondContact O-CE2 3.39Å; N265-F277 VanDerWaalsContact OD1-CD2 3.3Å; N265-F277 WeakPolarHBondContact OD1-CD2 3.34Å; F277-P279 HydrophobicContact CD1-CB 4.38Å; F277-P279 HydrophobicContact CD1-CG 4.48Å; F277-P279 HydrophobicContact CE1-CB 3.65Å; F277-P279 HydrophobicContact CE1-CG 4.15Å; F277-P279 HydrophobicContact CZ-CB 3.88Å
278D94.5Very high95.1Very high70 Ų7063.8 Ų63.837%0.37432%0.316SS..  trans-125.686.8-179.6-177.217.1000107.4N265 R266 Q276N265-D278 CarbonylContact C-O 3.5Å; N265-D278 WeakPolarHBondContact CA-O 3.23Å; N265-D278 PolarHBondContact OD1-N 2.94Å; N265-D278 PolarHBondContact OD1-O 3.2Å; R266-D278 VanDerWaalsContact CD-OD2 3.28Å; R266-D278 WeakPolarHBondContact CD-OD2 3.3Å; R266-D278 PolarHBondContact N-O 2.87Å; Q276-D278 PolarHBondContact O-N 3.13Å
279P95.4Very high95.2Very high41 Ų4160.7 Ų60.727%0.26631%0.308SS..BIsolated β-bridgetrans-63.8144.8-169.424-32.1000111.9G264 R266 F277G264-P279 CarbonylContact O-C 3.2Å; G264-P279 VanDerWaalsContact O-CA 3.3Å; G264-P279 WeakPolarHBondContact O-CA 2.87Å; R266-P279 WeakPolarHBondContact CG-O 2.96Å; F277-P279 HydrophobicContact CD1-CB 4.38Å; F277-P279 HydrophobicContact CD1-CG 4.48Å; F277-P279 HydrophobicContact CE1-CB 3.65Å; F277-P279 HydrophobicContact CE1-CG 4.15Å; F277-P279 HydrophobicContact CZ-CB 3.88Å
280Q96.3Very high95.2Very high22 Ų2262 Ų6210%0.10332%0.318CS..  trans-58.4134.8167.7-173.570.4-38.900109.4G264 N267 D282G264-Q280 PolarHBondContact O-N 2.91Å; N267-Q280 PolarHBondContact ND2-NE2 2.84Å; Q280-D282 WeakPolarHBondContact CG-OD1 3.24Å; Q280-D282 PolarHBondContact O-N 3.24Å
281P95.4Very high95.3Very high74 Ų7462.2 Ų62.248%0.48132%0.32SS..SBendtrans-81.841.7-172.936.8-36.5000112.1F253F253-P281 WeakPolarHBondContact CD2-O 3.47Å
282D97.2Very high95.4Very high21 Ų2160.5 Ų60.511%0.11232%0.318CS..SBendtrans-156.3-176176.966.137.4000110.2Q91 F253 Q280 S284 G285Q91-D282 HydrophobicContact CB-CB 3.89Å; Q91-D282 HydrophobicContact CG-CB 4.4Å; Q91-D282 WeakPolarHBondContact O-CB 3.43Å; F253-D282 HydrophobicContact CD2-CB 4.38Å; F253-D282 HydrophobicContact CE2-CB 3.99Å; F253-D282 HydrophobicContact CZ-CB 4.13Å; Q280-D282 WeakPolarHBondContact CG-OD1 3.24Å; Q280-D282 PolarHBondContact O-N 3.24Å; D282-S284 PolarHBondContact O-N 3.26Å; D282-S284 VanDerWaalsContact O-N 3.07Å; D282-S284 WeakPolarHBondContact OD1-CA 3.15Å; D282-S284 WeakPolarHBondContact OD1-CB 3.49Å; D282-S284 PolarHBondContact OD1-N 2.64Å; D282-S284 PolarHBondContact OD1-OG 2.6Å; D282-G285 PolarHBondContact O-N 3.23Å
283A97.8Very high95.5Very high0 Ų056.5 Ų56.50%030%0.3CS..G310 helixtrans-59.6-21.9-177.300000113.5Q91 T94 I248 F253 G285 W286Q91-A283 WeakPolarHBondContact O-CB 3.44Å; Q91-A283 PolarHBondContact O-N 3.24Å; T94-A283 WeakPolarHBondContact CB-O 3.37Å; T94-A283 HydrophobicContact CG2-CB 4.48Å; T94-A283 VanDerWaalsContact CG2-O 3.29Å; T94-A283 WeakPolarHBondContact CG2-O 3.43Å; I248-A283 HydrophobicContact CB-CB 4.22Å; I248-A283 HydrophobicContact CG1-CB 4.46Å; F253-A283 HydrophobicContact CE1-CB 4.27Å; A283-G285 PolarHBondContact O-N 3.19Å; A283-G285 VanDerWaalsContact O-N 3.12Å; A283-W286 PolarHBondContact O-N 2.89Å
284S96.5Very high95.6Very high7 Ų755 Ų555%0.04929%0.289CS..G310 helixtrans-62.2-19.1175.6-42.70000112.3D282 W286 Q287D282-S284 PolarHBondContact O-N 3.26Å; D282-S284 VanDerWaalsContact O-N 3.07Å; D282-S284 WeakPolarHBondContact OD1-CA 3.15Å; D282-S284 WeakPolarHBondContact OD1-CB 3.49Å; D282-S284 PolarHBondContact OD1-N 2.64Å; D282-S284 PolarHBondContact OD1-OG 2.6Å; S284-W286 PolarHBondContact O-N 2.79Å; S284-Q287 WeakPolarHBondContact O-CB 3.43Å; S284-Q287 WeakPolarHBondContact O-CG 3.32Å; S284-Q287 PolarHBondContact O-N 3.08Å; S284-Q287 VanDerWaalsContact O-N 3.13Å; S284-Q287 PolarHBondContact O-NE2 3.5Å
285G96.9Very high95.8Very high0 Ų050.2 Ų50.20%027%0.272CS..G310 helixtrans-59.2-22.7172.500000114P257 G264 D282 A283 Q287P257-G285 WeakPolarHBondContact CG-O 3.5Å; G264-G285 WeakPolarHBondContact CA-O 2.93Å; G264-G285 WeakPolarHBondContact O-CA 3.1Å; D282-G285 PolarHBondContact O-N 3.23Å; A283-G285 PolarHBondContact O-N 3.19Å; A283-G285 VanDerWaalsContact O-N 3.12Å; G285-Q287 VanDerWaalsContact C-N 3.34Å
286W97.3Very high95.9Very high3 Ų340.7 Ų40.71%0.01123%0.228CC..G310 helixtrans-87.25178.2-80.5-103.9000114.3T109 L246 I248 K255 P257 A283 S284T109-W286 HydrophobicContact CG2-CZ2 3.61Å; T109-W286 VanDerWaalsContact CG2-NE1 3.35Å; T109-W286 PolarHBondContact OG1-NE1 3.33Å; L246-W286 HydrophobicContact CD2-CB 3.76Å; L246-W286 HydrophobicContact CD2-CG 4.23Å; I248-W286 HydrophobicContact CG1-CD2 4.13Å; I248-W286 HydrophobicContact CG1-CE3 4.34Å; I248-W286 HydrophobicContact CG1-CG 4.4Å; I248-W286 HydrophobicContact CG2-CH2 4.3Å; I248-W286 HydrophobicContact CG2-CZ2 4.49Å; I248-W286 HydrophobicContact CG2-CZ3 4.41Å; K255-W286 HydrophobicContact CB-CH2 4.48Å; K255-W286 HydrophobicContact CB-CZ2 4.31Å; K255-W286 VanDerWaalsContact O-CH2 3.29Å; K255-W286 WeakPolarHBondContact O-CH2 3.32Å; P257-W286 HydrophobicContact CB-CD2 4.17Å; P257-W286 HydrophobicContact CB-CG 4.04Å; P257-W286 HydrophobicContact CG-CD2 3.9Å; P257-W286 HydrophobicContact CG-CE3 4.22Å; P257-W286 HydrophobicContact CG-CG 4.19Å; P257-W286 HydrophobicContact CG-CZ2 4.39Å; A283-W286 PolarHBondContact O-N 2.89Å; S284-W286 PolarHBondContact O-N 2.79Å
287Q96.6Very high96.1Very high13 Ų1332.9 Ų32.96%0.06119%0.191CC..  trans-69.6133.1169.9-68179.595.400110.7T94 T96 F263 G264 S284 G285T94-Q287 VanDerWaalsContact OG1-CG 3.23Å; T94-Q287 WeakPolarHBondContact OG1-CG 3.3Å; T96-Q287 HydrophobicContact CG2-CG 4.39Å; F263-Q287 HydrophobicContact CB-CB 4.06Å; G264-Q287 WeakPolarHBondContact CA-O 3.26Å; G264-Q287 PolarHBondContact N-O 3.37Å; S284-Q287 WeakPolarHBondContact O-CB 3.43Å; S284-Q287 WeakPolarHBondContact O-CG 3.32Å; S284-Q287 PolarHBondContact O-N 3.08Å; S284-Q287 VanDerWaalsContact O-N 3.13Å; S284-Q287 PolarHBondContact O-NE2 3.5Å; G285-Q287 VanDerWaalsContact C-N 3.34Å
288I95.6Very high96.2Very high70 Ų7029.9 Ų29.936%0.35918%0.178SC..  trans-96.8-57.1-177.7-53.4177.8000110.1L259 G261 W262L259-I288 HydrophobicContact CB-CD1 3.8Å; L259-I288 HydrophobicContact CB-CG1 4.41Å; L259-I288 HydrophobicContact CD1-CD1 4.22Å; G261-I288 CarbonylContact C-O 3.59Å; G261-I288 VanDerWaalsContact C-O 3.26Å; G261-I288 WeakPolarHBondContact CA-O 3.49Å; W262-I288 PolarHBondContact N-O 3.44Å
289G94.2Very high96.4Very high33 Ų3326.5 Ų26.534%0.3416%0.161SC..SBendtrans-114.2179.5-17800000112.6F263F263-G289 WeakPolarHBondContact CB-O 3.23Å
290S94.4Very high96.5Very high54 Ų5425.5 Ų25.538%0.37815%0.152SC..  trans-59.2143.9175.8-44.40000111.9W262 F263W262-S290 WeakPolarHBondContact CZ2-OG 3.5Å; F263-S290 VanDerWaalsContact CD2-CA 3.42Å; F263-S290 VanDerWaalsContact CE2-CA 3.44Å; F263-S290 VanDerWaalsContact CE2-CB 3.48Å; F263-S290 WeakPolarHBondContact CE2-OG 3.43Å
291P94.7Very high96.5Very high11 Ų1124.5 Ų24.57%0.07115%0.147CC..  trans-64.4143.4-177.425.9-35.4000111.6W68 F263 I293 M296W68-P291 HydrophobicContact CH2-CG 4.34Å; W68-P291 HydrophobicContact CZ3-CG 4.09Å; F263-P291 HydrophobicContact CD1-CG 4.38Å; F263-P291 HydrophobicContact CE1-CG 3.93Å; P291-I293 VanDerWaalsContact C-N 3.27Å; P291-I293 HydrophobicContact CB-CD1 4.03Å; P291-I293 HydrophobicContact CG-CD1 3.72Å; P291-I293 HydrophobicContact CG-CG1 4.46Å; P291-I293 PolarHBondContact O-N 3.33Å; P291-M296 HydrophobicContact CB-CE 3.53Å; P291-M296 HydrophobicContact CB-SD 3.72Å
292T95.6Very high96.6Very high72 Ų7221 Ų2144%0.44213%0.125SC..  trans-81.372.1178.148.70000110.6T243 F294 S295 M296T243-T292 VanDerWaalsContact CB-OG1 3.31Å; T243-T292 WeakPolarHBondContact CB-OG1 3.33Å; T292-F294 VanDerWaalsContact C-N 3.34Å; T292-F294 PolarHBondContact O-N 3.15Å; T292-F294 VanDerWaalsContact O-N 3.13Å; T292-S295 WeakPolarHBondContact O-CA 3.29Å; T292-S295 WeakPolarHBondContact O-CB 3.46Å; T292-S295 PolarHBondContact O-N 3.25Å; T292-M296 PolarHBondContact O-N 3.1Å
293I96.6Very high96.6Very high20 Ų2020 Ų2010%0.10312%0.119CC..Hα-helixtrans-48.3-45.4-168.6-62.3-56.9000114.4M56 W68 L71 Y74 P291 S295 M296 A297M56-I293 HydrophobicContact CE-CG2 3.74Å; M56-I293 HydrophobicContact CG-CG2 3.5Å; M56-I293 VanDerWaalsContact CG-CG2 3.5Å; M56-I293 HydrophobicContact SD-CG2 3.41Å; M56-I293 WeakPolarHBondContact SD-CG2 3.38Å; W68-I293 HydrophobicContact CH2-CG1 4.23Å; L71-I293 HydrophobicContact CB-CD1 4.06Å; L71-I293 HydrophobicContact CD1-CG2 4.14Å; L71-I293 HydrophobicContact CD2-CG2 4.42Å; L71-I293 WeakPolarHBondContact O-CD1 3.4Å; Y74-I293 HydrophobicContact CD1-CD1 3.91Å; Y74-I293 HydrophobicContact CG-CD1 4.34Å; P291-I293 VanDerWaalsContact C-N 3.27Å; P291-I293 HydrophobicContact CB-CD1 4.03Å; P291-I293 HydrophobicContact CG-CD1 3.72Å; P291-I293 HydrophobicContact CG-CG1 4.46Å; P291-I293 PolarHBondContact O-N 3.33Å; I293-S295 VanDerWaalsContact C-N 3.33Å; I293-S295 PolarHBondContact O-N 2.95Å; I293-M296 PolarHBondContact O-N 2.82Å; I293-A297 WeakPolarHBondContact O-CB 3.35Å; I293-A297 PolarHBondContact O-N 3.43Å
294F96.3Very high96.5Very high84 Ų8424.1 Ų24.137%0.36814%0.139SC..Hα-helixtrans-66.6-34.8179.2-62.4-47000113M56 I57 W60 T292 A297 G298M56-F294 HydrophobicContact CB-CD1 4.19Å; M56-F294 HydrophobicContact CB-CE1 4.36Å; M56-F294 HydrophobicContact CG-CD1 3.78Å; M56-F294 HydrophobicContact CG-CE1 3.87Å; I57-F294 HydrophobicContact CG1-CD1 4.31Å; I57-F294 HydrophobicContact CG1-CE1 3.98Å; W60-F294 HydrophobicContact CB-CZ 4.47Å; W60-F294 HydrophobicContact CD2-CZ 4.05Å; W60-F294 HydrophobicContact CE3-CE1 4.44Å; W60-F294 HydrophobicContact CE3-CE2 4.11Å; W60-F294 AromaticContact CE3-CZ 3.45Å; W60-F294 HydrophobicContact CE3-CZ 3.45Å; W60-F294 VanDerWaalsContact CE3-CZ 3.45Å; W60-F294 HydrophobicContact CZ3-CE2 4.13Å; W60-F294 AromaticContact CZ3-CZ 3.93Å; W60-F294 HydrophobicContact CZ3-CZ 3.93Å; T292-F294 VanDerWaalsContact C-N 3.34Å; T292-F294 PolarHBondContact O-N 3.15Å; T292-F294 VanDerWaalsContact O-N 3.13Å; F294-A297 PolarHBondContact O-N 2.8Å; F294-G298 PolarHBondContact O-N 2.95Å
295S96.9Very high96.5Very high31 Ų3124.3 Ų24.322%0.21714%0.139CC..Hα-helixtrans-69-43.5174.5-179.50000111.3S242 T243 T292 I293 A297 G298 L299S242-S295 WeakPolarHBondContact CA-OG 3.44Å; S242-S295 WeakPolarHBondContact CB-OG 3.48Å; T243-S295 PolarHBondContact N-OG 2.88Å; T292-S295 WeakPolarHBondContact O-CA 3.29Å; T292-S295 WeakPolarHBondContact O-CB 3.46Å; T292-S295 PolarHBondContact O-N 3.25Å; I293-S295 VanDerWaalsContact C-N 3.33Å; I293-S295 PolarHBondContact O-N 2.95Å; S295-A297 VanDerWaalsContact C-N 3.28Å; S295-A297 PolarHBondContact O-N 3.26Å; S295-G298 PolarHBondContact O-N 3.09Å; S295-L299 PolarHBondContact O-N 3.24Å; S295-L299 VanDerWaalsContact O-N 3.1Å
296M97.7Very high96.5Very high0 Ų024.4 Ų24.40%014%0.14CC..Hα-helixtrans-60.9-36.9174-72.4-178.1174.500112.3Y74 I78 V95 T243 P291 T292 I293 L299 E300Y74-M296 HydrophobicContact CD1-CB 3.67Å; Y74-M296 HydrophobicContact CD1-CG 4.44Å; Y74-M296 HydrophobicContact CD1-SD 3.89Å; Y74-M296 HydrophobicContact CE1-CB 3.49Å; Y74-M296 VanDerWaalsContact CE1-CB 3.49Å; I78-M296 HydrophobicContact CD1-CB 4.42Å; I78-M296 HydrophobicContact CG1-CB 4Å; I78-M296 HydrophobicContact CG1-CG 4.25Å; I78-M296 HydrophobicContact CG1-SD 4.43Å; V95-M296 HydrophobicContact CB-CE 4.2Å; V95-M296 HydrophobicContact CG1-CE 4.21Å; V95-M296 WeakPolarHBondContact O-CE 3.47Å; T243-M296 HydrophobicContact CG2-CG 3.8Å; P291-M296 HydrophobicContact CB-CE 3.53Å; P291-M296 HydrophobicContact CB-SD 3.72Å; T292-M296 PolarHBondContact O-N 3.1Å; I293-M296 PolarHBondContact O-N 2.82Å; M296-L299 PolarHBondContact O-N 3.18Å; M296-E300 PolarHBondContact O-N 2.93Å
297A97.3Very high96.5Very high0 Ų027 Ų270%015%0.153CC..Hα-helixtrans-64.1-46.2178.100000111.8S52 I53 M56 Y74 I293 F294 S295 L299 E300 G301S52-A297 WeakPolarHBondContact CB-O 3.35Å; S52-A297 PolarHBondContact OG-O 3.48Å; I53-A297 HydrophobicContact CG1-CB 4.44Å; M56-A297 HydrophobicContact CB-CB 3.84Å; M56-A297 HydrophobicContact CE-CB 4.22Å; M56-A297 HydrophobicContact CG-CB 4.16Å; Y74-A297 WeakPolarHBondContact OH-CA 3.28Å; I293-A297 WeakPolarHBondContact O-CB 3.35Å; I293-A297 PolarHBondContact O-N 3.43Å; F294-A297 PolarHBondContact O-N 2.8Å; S295-A297 VanDerWaalsContact C-N 3.28Å; S295-A297 PolarHBondContact O-N 3.26Å; A297-L299 VanDerWaalsContact C-N 3.32Å; A297-L299 PolarHBondContact O-N 2.94Å; A297-E300 WeakPolarHBondContact O-CB 3.27Å; A297-E300 PolarHBondContact O-N 3.05Å; A297-G301 PolarHBondContact O-N 2.95Å
298G97Very high96.5Very high1 Ų133.1 Ų33.11%0.0118%0.182CC..Hα-helixtrans-59-44.8174.200000112.1A49 F294 S295 E300 G301 S302A49-G298 WeakPolarHBondContact CA-O 3.09Å; A49-G298 WeakPolarHBondContact CB-O 3.3Å; F294-G298 PolarHBondContact O-N 2.95Å; S295-G298 PolarHBondContact O-N 3.09Å; G298-E300 PolarHBondContact O-N 2.89Å; G298-G301 PolarHBondContact O-N 3.18Å; G298-S302 PolarHBondContact O-N 3.17Å
299L97.8Very high96.5Very high0 Ų030.6 Ų30.60%017%0.169CC..Hα-helixtrans-61.9-40.2175.7-178.657.8000112.7I78 M82 V95 T232 S295 M296 A297 G301 S302 L303I78-L299 HydrophobicContact CG2-CD2 3.71Å; I78-L299 HydrophobicContact CG2-CG 4.13Å; M82-L299 HydrophobicContact CE-CD2 4.1Å; V95-L299 HydrophobicContact CG1-CD2 4.2Å; T232-L299 HydrophobicContact CG2-CD1 4.22Å; T232-L299 HydrophobicContact CG2-CD2 3.77Å; S295-L299 PolarHBondContact O-N 3.24Å; S295-L299 VanDerWaalsContact O-N 3.1Å; M296-L299 PolarHBondContact O-N 3.18Å; A297-L299 VanDerWaalsContact C-N 3.32Å; A297-L299 PolarHBondContact O-N 2.94Å; L299-G301 VanDerWaalsContact C-N 3.32Å; L299-G301 PolarHBondContact O-N 3.04Å; L299-S302 PolarHBondContact O-N 2.84Å; L299-L303 HydrophobicContact CD1-CD1 3.96Å; L299-L303 HydrophobicContact CD1-CD2 4.23Å; L299-L303 HydrophobicContact CD1-CG 3.76Å; L299-L303 HydrophobicContact CD2-CD1 4.31Å; L299-L303 HydrophobicContact CG-CD1 3.71Å; L299-L303 HydrophobicContact CG-CG 4.01Å; L299-L303 WeakPolarHBondContact O-CB 3.42Å; L299-L303 VanDerWaalsContact O-CG 3.31Å; L299-L303 WeakPolarHBondContact O-CG 3.35Å; L299-L303 PolarHBondContact O-N 3.31Å
300E97.8Very high96.6Very high20 Ų2030.4 Ų30.49%0.09317%0.167CC..Hα-helixtrans-53.9-50.2175.2-175.4-175.4156.600110.9Y74 K77 I78 L81 M296 A297 G298 S302 L303 Q304Y74-E300 WeakPolarHBondContact CE2-OE2 3.37Å; Y74-E300 VanDerWaalsContact CZ-OE2 3.29Å; Y74-E300 PolarHBondContact OH-OE2 2.72Å; K77-E300 VanDerWaalsContact CE-OE1 3.31Å; K77-E300 WeakPolarHBondContact CE-OE1 3.37Å; K77-E300 IonicContact NZ-OE1 3.18Å; K77-E300 PolarHBondContact NZ-OE1 2.63Å; K77-E300 IonicContact NZ-OE2 3.83Å; K77-E300 PolarHBondContact NZ-OE2 2.88Å; I78-E300 HydrophobicContact CD1-CB 3.74Å; I78-E300 HydrophobicContact CD1-CG 4.28Å; L81-E300 HydrophobicContact CD1-CG 3.8Å; M296-E300 PolarHBondContact O-N 2.93Å; A297-E300 WeakPolarHBondContact O-CB 3.27Å; A297-E300 PolarHBondContact O-N 3.05Å; G298-E300 PolarHBondContact O-N 2.89Å; E300-S302 VanDerWaalsContact C-N 3.3Å; E300-S302 PolarHBondContact O-N 2.8Å; E300-L303 PolarHBondContact O-N 3.36Å; E300-Q304 WeakPolarHBondContact O-CG 3.42Å; E300-Q304 PolarHBondContact O-N 2.88Å; E300-Q304 VanDerWaalsContact O-N 3.1Å; E300-Q304 PolarHBondContact OE1-NE2 3.34Å
301G96.7Very high96.8Very high0 Ų028.6 Ų28.60%015%0.153CC..Hα-helixtrans-62.5-37.2-178.600000112.7A48 A297 G298 L299A48-G301 WeakPolarHBondContact CB-O 3.32Å; A297-G301 PolarHBondContact O-N 2.95Å; G298-G301 PolarHBondContact O-N 3.18Å; L299-G301 VanDerWaalsContact C-N 3.32Å; L299-G301 PolarHBondContact O-N 3.04Å
302S97.1Very high96.9Very high0 Ų035.4 Ų35.40%018%0.181CC..Hα-helixtrans-68.6-49.1173.6-175.70000112.4L236 G298 L299 E300 Q304 I305 F306L236-S302 VanDerWaalsContact O-CB 3.29Å; L236-S302 WeakPolarHBondContact O-CB 3.32Å; L236-S302 PolarHBondContact O-OG 3.44Å; G298-S302 PolarHBondContact O-N 3.17Å; L299-S302 PolarHBondContact O-N 2.84Å; E300-S302 VanDerWaalsContact C-N 3.3Å; E300-S302 PolarHBondContact O-N 2.8Å; S302-Q304 PolarHBondContact O-N 2.87Å; S302-Q304 VanDerWaalsContact O-N 3.15Å; S302-I305 WeakPolarHBondContact O-CB 3.2Å; S302-I305 PolarHBondContact O-N 2.99Å; S302-F306 WeakPolarHBondContact O-CD2 2.88Å; S302-F306 PolarHBondContact O-N 3.31Å
303L97.9Very high96.9Very high0 Ų037.3 Ų37.30%018%0.184CC..Hα-helixtrans-62.1-24.9-177.2-71.4175.7000113.3I78 L81 M82 L85 L236 L299 E300 I305 F306 N307I78-L303 HydrophobicContact CG2-CD1 3.84Å; L81-L303 HydrophobicContact CB-CB 3.99Å; L81-L303 HydrophobicContact CB-CD1 3.79Å; L81-L303 HydrophobicContact CD1-CB 4.4Å; M82-L303 HydrophobicContact CG-CD1 3.6Å; M82-L303 HydrophobicContact CG-CD2 4.29Å; L85-L303 HydrophobicContact CD1-CD2 3.65Å; L236-L303 HydrophobicContact CD1-CD2 4.42Å; L236-L303 HydrophobicContact CD2-CD2 4.36Å; L299-L303 HydrophobicContact CD1-CD1 3.96Å; L299-L303 HydrophobicContact CD1-CD2 4.23Å; L299-L303 HydrophobicContact CD1-CG 3.76Å; L299-L303 HydrophobicContact CD2-CD1 4.31Å; L299-L303 HydrophobicContact CG-CD1 3.71Å; L299-L303 HydrophobicContact CG-CG 4.01Å; L299-L303 WeakPolarHBondContact O-CB 3.42Å; L299-L303 VanDerWaalsContact O-CG 3.31Å; L299-L303 WeakPolarHBondContact O-CG 3.35Å; L299-L303 PolarHBondContact O-N 3.31Å; E300-L303 PolarHBondContact O-N 3.36Å; L303-I305 VanDerWaalsContact C-N 3.31Å; L303-I305 PolarHBondContact O-N 2.89Å; L303-F306 PolarHBondContact O-N 3.23Å; L303-N307 WeakPolarHBondContact O-CB 3.29Å; L303-N307 PolarHBondContact O-N 3Å; L303-N307 PolarHBondContact O-ND2 3.38Å
304Q96.3Very high97Very high87 Ų8736.7 Ų36.741%0.40718%0.18SC..Hα-helixtrans-59.4-42.1172.4-75170.23.500111.7E300 S302 N307 Q308E300-Q304 WeakPolarHBondContact O-CG 3.42Å; E300-Q304 PolarHBondContact O-N 2.88Å; E300-Q304 VanDerWaalsContact O-N 3.1Å; E300-Q304 PolarHBondContact OE1-NE2 3.34Å; S302-Q304 PolarHBondContact O-N 2.87Å; S302-Q304 VanDerWaalsContact O-N 3.15Å; Q304-N307 PolarHBondContact O-N 3.43Å; Q304-Q308 WeakPolarHBondContact O-CB 3.42Å; Q304-Q308 PolarHBondContact O-N 3.12Å
305I95.7Very high97Very high11 Ų1133.5 Ų33.56%0.05617%0.166CC..Hα-helixtrans-63.5-45.3176.7-57.2172.4000109.9Y24 F28 A48 S302 L303 N307 Q308 L309 L389Y24-I305 HydrophobicContact CD1-CG2 3.98Å; Y24-I305 HydrophobicContact CE1-CG2 4.2Å; F28-I305 HydrophobicContact CE2-CD1 4.48Å; F28-I305 HydrophobicContact CZ-CD1 4.14Å; A48-I305 HydrophobicContact CB-CD1 4.47Å; S302-I305 WeakPolarHBondContact O-CB 3.2Å; S302-I305 PolarHBondContact O-N 2.99Å; L303-I305 VanDerWaalsContact C-N 3.31Å; L303-I305 PolarHBondContact O-N 2.89Å; I305-N307 PolarHBondContact O-N 3.27Å; I305-Q308 PolarHBondContact O-N 2.82Å; I305-L309 HydrophobicContact CG2-CD1 3.99Å; I305-L309 PolarHBondContact O-N 2.65Å; I305-L389 HydrophobicContact CG2-CD1 4.16Å; I305-L389 HydrophobicContact CG2-CD2 4.3Å
306F97.4Very high97Very high3 Ų333.9 Ų33.91%0.01317%0.17CC..Hα-helixtrans-62.1-44178-78.2-91.3000112.9L85 Y235 L236 S302 L303 L309 G310 M311 I314 L389L85-F306 HydrophobicContact CD2-CB 4Å; L85-F306 HydrophobicContact CD2-CD1 4.17Å; L85-F306 HydrophobicContact CD2-CG 4.39Å; Y235-F306 WeakPolarHBondContact O-CZ 3.44Å; L236-F306 HydrophobicContact CD2-CD1 4.08Å; L236-F306 HydrophobicContact CD2-CD2 4.27Å; L236-F306 HydrophobicContact CD2-CE1 3.9Å; L236-F306 HydrophobicContact CD2-CE2 4.1Å; L236-F306 HydrophobicContact CD2-CG 4.29Å; L236-F306 HydrophobicContact CD2-CZ 3.94Å; S302-F306 WeakPolarHBondContact O-CD2 2.88Å; S302-F306 PolarHBondContact O-N 3.31Å; L303-F306 PolarHBondContact O-N 3.23Å; F306-L309 PolarHBondContact O-N 2.68Å; F306-G310 WeakPolarHBondContact O-CA 3.42Å; F306-G310 PolarHBondContact O-N 2.74Å; F306-M311 HydrophobicContact CD1-SD 3.93Å; F306-M311 HydrophobicContact CE1-SD 4.32Å; F306-I314 HydrophobicContact CD1-CD1 3.48Å; F306-I314 VanDerWaalsContact CD1-CD1 3.48Å; F306-I314 HydrophobicContact CE1-CD1 3.82Å; F306-I314 HydrophobicContact CG-CD1 4.25Å; F306-L389 HydrophobicContact CE2-CD1 4.17Å; F306-L389 HydrophobicContact CZ-CD1 4.05Å
307N97Very high97Very high57 Ų5734.6 Ų34.631%0.30517%0.174SC..Hα-helixtrans-68.3-35.8178.3-80.7-71.8000112.4L81 P84 L303 Q304 I305L81-N307 PolarHBondContact O-ND2 3.28Å; P84-N307 WeakPolarHBondContact CG-OD1 3.17Å; L303-N307 WeakPolarHBondContact O-CB 3.29Å; L303-N307 PolarHBondContact O-N 3Å; L303-N307 PolarHBondContact O-ND2 3.38Å; Q304-N307 PolarHBondContact O-N 3.43Å; I305-N307 PolarHBondContact O-N 3.27Å
308Q95.8Very high97Very high141 Ų14134.9 Ų34.966%0.65918%0.177SC*.Hα-helixtrans-65-40.9176177.2176.7-22.400112.1Y24 Q304 I305Y24-Q308 PolarHBondContact OH-NE2 2.65Å; Y24-Q308 VanDerWaalsContact OH-NE2 3.1Å; Q304-Q308 WeakPolarHBondContact O-CB 3.42Å; Q304-Q308 PolarHBondContact O-N 3.12Å; I305-Q308 PolarHBondContact O-N 2.82Å
309L96.3Very high97Very high18 Ų1836.5 Ų36.59%0.09419%0.185CC..Hα-helixtrans-85.4-39.2-176.8-72.9175.7000113.7L21 Y24 I305 F306 I314 L389L21-L309 HydrophobicContact CD2-CD1 4.12Å; L21-L309 HydrophobicContact CD2-CD2 3.52Å; L21-L309 HydrophobicContact CD2-CG 4.43Å; Y24-L309 HydrophobicContact CD1-CD1 4.41Å; Y24-L309 HydrophobicContact CD2-CD1 4.3Å; Y24-L309 HydrophobicContact CD2-CD2 4.49Å; Y24-L309 HydrophobicContact CE1-CD1 4.21Å; Y24-L309 HydrophobicContact CE1-CD2 4.44Å; Y24-L309 HydrophobicContact CE1-CG 4.37Å; Y24-L309 HydrophobicContact CE2-CD1 4.14Å; Y24-L309 HydrophobicContact CE2-CD2 3.63Å; Y24-L309 HydrophobicContact CE2-CG 4.3Å; Y24-L309 HydrophobicContact CG-CD1 4.43Å; Y24-L309 WeakPolarHBondContact OH-CD2 3.26Å; I305-L309 HydrophobicContact CG2-CD1 3.99Å; I305-L309 PolarHBondContact O-N 2.65Å; F306-L309 PolarHBondContact O-N 2.68Å; L309-I314 HydrophobicContact CB-CD1 4.11Å; L309-I314 HydrophobicContact CB-CG1 4.07Å; L309-I314 HydrophobicContact CD1-CD1 4.48Å; L309-I314 HydrophobicContact CD1-CG1 4.31Å; L309-L389 HydrophobicContact CD1-CD2 3.32Å
310G96.9Very high96.9Very high28 Ų2837.8 Ų37.829%0.28919%0.192SC..  trans74.5145.7-170.700000113.3F306 K312 K313 I314F306-G310 WeakPolarHBondContact O-CA 3.42Å; F306-G310 PolarHBondContact O-N 2.74Å; G310-K312 VanDerWaalsContact C-N 3.27Å; G310-K312 PolarHBondContact O-N 2.89Å; G310-K313 PolarHBondContact O-N 3.3Å; G310-I314 PolarHBondContact O-N 3.28Å
311M97.4Very high96.9Very high16 Ų1637 Ų378%0.07919%0.188CC..Hα-helixtrans-61.8-29.6-175.2-76.1-52.3-57.700114.3L85 G214 I216 E217 F306 K313 I314 R315L85-M311 HydrophobicContact CD2-CG 3.87Å; L85-M311 HydrophobicContact CD2-SD 3.91Å; G214-M311 VanDerWaalsContact C-CE 3.46Å; I216-M311 WeakPolarHBondContact O-CE 3.47Å; E217-M311 HydrophobicContact CG-CB 4.18Å; F306-M311 HydrophobicContact CD1-SD 3.93Å; F306-M311 HydrophobicContact CE1-SD 4.32Å; M311-K313 PolarHBondContact O-N 2.88Å; M311-I314 HydrophobicContact CE-CG2 4.27Å; M311-I314 PolarHBondContact O-N 2.89Å; M311-I314 HydrophobicContact SD-CD1 4.17Å; M311-R315 VanDerWaalsContact O-CB 3.24Å; M311-R315 WeakPolarHBondContact O-CB 3.25Å; M311-R315 PolarHBondContact O-N 3.44Å
312K97Very high96.9Very high154 Ų15437 Ų3767%0.6719%0.188SC*.Hα-helixtrans-56.6-47.4175.8-78179.5-179.7-1740112.9E217 G310 A316E217-K312 WeakPolarHBondContact OE2-CE 3.42Å; E217-K312 WeakPolarHBondContact OE2-CG 3.38Å; G310-K312 VanDerWaalsContact C-N 3.27Å; G310-K312 PolarHBondContact O-N 2.89Å; K312-A316 VanDerWaalsContact O-CB 3.25Å; K312-A316 WeakPolarHBondContact O-CB 3.48Å; K312-A316 PolarHBondContact O-N 3.41Å
313K96.9Very high96.8Very high113 Ų11338.2 Ų38.249%0.49120%0.198SC..Hα-helixtrans-69.8-44179.8-69.1-168177.1-1660111.2G310 M311 A316 N317G310-K313 PolarHBondContact O-N 3.3Å; M311-K313 PolarHBondContact O-N 2.88Å; K313-A316 PolarHBondContact O-N 2.85Å; K313-N317 WeakPolarHBondContact O-CB 3.28Å; K313-N317 PolarHBondContact O-N 3.41Å
314I97.7Very high96.8Very high7 Ų738.2 Ų38.24%0.03620%0.198CC..Hα-helixtrans-59.9-48.9178.6-65.7174.3000110.5F306 L309 G310 M311 N317 S318 A388 L389F306-I314 HydrophobicContact CD1-CD1 3.48Å; F306-I314 VanDerWaalsContact CD1-CD1 3.48Å; F306-I314 HydrophobicContact CE1-CD1 3.82Å; F306-I314 HydrophobicContact CG-CD1 4.25Å; L309-I314 HydrophobicContact CB-CD1 4.11Å; L309-I314 HydrophobicContact CB-CG1 4.07Å; L309-I314 HydrophobicContact CD1-CD1 4.48Å; L309-I314 HydrophobicContact CD1-CG1 4.31Å; G310-I314 PolarHBondContact O-N 3.28Å; M311-I314 HydrophobicContact CE-CG2 4.27Å; M311-I314 PolarHBondContact O-N 2.89Å; M311-I314 HydrophobicContact SD-CD1 4.17Å; I314-N317 PolarHBondContact O-N 3.03Å; I314-S318 WeakPolarHBondContact O-CB 3.12Å; I314-S318 PolarHBondContact O-N 2.75Å; I314-A388 HydrophobicContact CG2-CB 4.04Å; I314-A388 WeakPolarHBondContact O-CB 3.43Å; I314-L389 HydrophobicContact CG1-CD2 4.47Å
315R97.3Very high96.9Very high17 Ų1734.1 Ų34.16%0.06418%0.179CC..Hα-helixtrans-65.1-44.8179.4179.755.3176.5173.91.8111.9A215 E217 M311 N317 S318 L319 D346 R349 G350A215-R315 WeakPolarHBondContact O-CD 3.03Å; E217-R315 HydrophobicContact CG-CB 4.2Å; E217-R315 HydrophobicContact CG-CG 4.46Å; M311-R315 VanDerWaalsContact O-CB 3.24Å; M311-R315 WeakPolarHBondContact O-CB 3.25Å; M311-R315 PolarHBondContact O-N 3.44Å; R315-N317 VanDerWaalsContact C-N 3.31Å; R315-N317 PolarHBondContact O-N 3.43Å; R315-S318 PolarHBondContact O-N 2.85Å; R315-L319 HydrophobicContact CG-CD1 4.18Å; R315-L319 HydrophobicContact CG-CG 4.42Å; R315-L319 VanDerWaalsContact CZ-CD2 3.4Å; R315-L319 VanDerWaalsContact NH2-CD2 3.33Å; R315-L319 WeakPolarHBondContact O-CB 3.38Å; R315-L319 WeakPolarHBondContact O-CG 3.43Å; R315-L319 PolarHBondContact O-N 2.77Å; R315-D346 PolarHBondContact NH2-O 3.13Å; R315-R349 PolarHBondContact NH1-O 3.39Å; R315-R349 PolarHBondContact NH2-O 2.84Å; R315-G350 PolarHBondContact NH1-O 3.41Å
316A96.7Very high97Very high38 Ų3834.2 Ų34.231%0.31418%0.179SC..Hα-helixtrans-59.3-41.9177.600000112.2M1 K312 K313 N320M1-A316 HydrophobicContact CE-CB 4.19Å; K312-A316 VanDerWaalsContact O-CB 3.25Å; K312-A316 WeakPolarHBondContact O-CB 3.48Å; K312-A316 PolarHBondContact O-N 3.41Å; K313-A316 PolarHBondContact O-N 2.85Å; A316-N320 PolarHBondContact O-N 3.21Å; A316-N320 VanDerWaalsContact O-N 3.13Å
317N97.1Very high96.9Very high15 Ų1536.1 Ų36.18%0.0819%0.188CC..Hα-helixtrans-67-47.7175.6-175-87.7000112.1D19 L21 K313 I314 R315 L319 N320 K321 A388D19-N317 VanDerWaalsContact CG-ND2 3.28Å; D19-N317 PolarHBondContact OD1-ND2 3.1Å; D19-N317 PolarHBondContact OD2-ND2 3.29Å; L21-N317 HydrophobicContact CD1-CB 3.63Å; L21-N317 HydrophobicContact CG-CB 4.33Å; K313-N317 WeakPolarHBondContact O-CB 3.28Å; K313-N317 PolarHBondContact O-N 3.41Å; I314-N317 PolarHBondContact O-N 3.03Å; R315-N317 VanDerWaalsContact C-N 3.31Å; R315-N317 PolarHBondContact O-N 3.43Å; N317-L319 VanDerWaalsContact C-N 3.31Å; N317-L319 PolarHBondContact O-N 2.81Å; N317-N320 PolarHBondContact O-N 2.84Å; N317-N320 VanDerWaalsContact O-N 3.1Å; N317-K321 PolarHBondContact O-N 3Å; N317-K321 VanDerWaalsContact OD1-CD 3.32Å; N317-K321 WeakPolarHBondContact OD1-CD 3.47Å; N317-K321 WeakPolarHBondContact OD1-CE 3.1Å; N317-K321 PolarHBondContact OD1-NZ 3.19Å; N317-A388 HydrophobicContact CB-CB 4.1Å; N317-A388 VanDerWaalsContact OD1-CA 3.23Å; N317-A388 WeakPolarHBondContact OD1-CA 3.43Å; N317-A388 WeakPolarHBondContact OD1-CB 3.12Å; N317-A388 PolarHBondContact OD1-O 2.94Å
318S96.7Very high97Very high7 Ų733.4 Ų33.45%0.04917%0.173CC..Hα-helixtrans-56.3-44.7177176.50000111.9I314 R315 K321 T322I314-S318 WeakPolarHBondContact O-CB 3.12Å; I314-S318 PolarHBondContact O-N 2.75Å; R315-S318 PolarHBondContact O-N 2.85Å; S318-K321 PolarHBondContact O-N 2.87Å; S318-T322 WeakPolarHBondContact O-CB 3.43Å; S318-T322 WeakPolarHBondContact O-CG2 3.38Å; S318-T322 PolarHBondContact O-N 2.76Å; S318-T322 PolarHBondContact O-OG1 2.99Å
319L96.7Very high97Very high35 Ų3527 Ų2718%0.18314%0.143CC..Hα-helixtrans-61-44.1175.4-76.7178000112R315 N317 T322 A323 D346R315-L319 HydrophobicContact CG-CD1 4.18Å; R315-L319 HydrophobicContact CG-CG 4.42Å; R315-L319 VanDerWaalsContact CZ-CD2 3.4Å; R315-L319 VanDerWaalsContact NH2-CD2 3.33Å; R315-L319 WeakPolarHBondContact O-CB 3.38Å; R315-L319 WeakPolarHBondContact O-CG 3.43Å; R315-L319 PolarHBondContact O-N 2.77Å; N317-L319 VanDerWaalsContact C-N 3.31Å; N317-L319 PolarHBondContact O-N 2.81Å; L319-T322 WeakPolarHBondContact CA-OG1 3.45Å; L319-T322 PolarHBondContact O-N 2.72Å; L319-T322 PolarHBondContact O-OG1 3Å; L319-T322 VanDerWaalsContact O-OG1 3.11Å; L319-A323 VanDerWaalsContact O-CB 3.24Å; L319-A323 WeakPolarHBondContact O-CB 3.33Å; L319-A323 PolarHBondContact O-N 2.87Å; L319-D346 HydrophobicContact CD1-CB 4.49Å; L319-D346 HydrophobicContact CD2-CB 3.67Å
320N96.2Very high97Very high27 Ų2730.3 Ų30.314%0.14416%0.161CC..Hα-helixtrans-64.9-44.7179-167-72000112.2A316 N317 A323 Y324 Y393A316-N320 PolarHBondContact O-N 3.21Å; A316-N320 VanDerWaalsContact O-N 3.13Å; N317-N320 PolarHBondContact O-N 2.84Å; N317-N320 VanDerWaalsContact O-N 3.1Å; N320-A323 PolarHBondContact O-N 2.98Å; N320-Y324 PolarHBondContact O-N 2.89Å; N320-Y393 VanDerWaalsContact CG-OH 3.31Å; N320-Y393 WeakPolarHBondContact OD1-CE1 3.36Å; N320-Y393 PolarHBondContact OD1-OH 2.96Å
321K97.2Very high97Very high2 Ų235.6 Ų35.61%0.00918%0.176CC..Hα-helixtrans-62.1-44.3176.6-76.2-177.7-179.2172.60112.2D19 N317 S318 Y324 L325 P386 A388 T391 Y393 I396D19-K321 WeakPolarHBondContact OD2-CE 3.49Å; D19-K321 IonicContact OD2-NZ 3.24Å; D19-K321 PolarHBondContact OD2-NZ 3.45Å; N317-K321 PolarHBondContact O-N 3Å; N317-K321 VanDerWaalsContact OD1-CD 3.32Å; N317-K321 WeakPolarHBondContact OD1-CD 3.47Å; N317-K321 WeakPolarHBondContact OD1-CE 3.1Å; N317-K321 PolarHBondContact OD1-NZ 3.19Å; S318-K321 PolarHBondContact O-N 2.87Å; K321-Y324 PolarHBondContact O-N 3.02Å; K321-L325 PolarHBondContact O-N 3.18Å; K321-P386 HydrophobicContact CB-CB 3.98Å; K321-A388 PolarHBondContact NZ-O 2.89Å; K321-T391 VanDerWaalsContact CE-O 3.22Å; K321-T391 WeakPolarHBondContact CE-O 3.49Å; K321-T391 PolarHBondContact NZ-O 3.14Å; K321-Y393 HydrophobicContact CD-CE2 4.48Å; K321-Y393 HydrophobicContact CG-CE1 3.97Å; K321-Y393 HydrophobicContact CG-CE2 3.9Å; K321-I396 HydrophobicContact CB-CD1 3.72Å; K321-I396 HydrophobicContact CD-CD1 4.43Å; K321-I396 HydrophobicContact CG-CD1 4Å
322T97.1Very high97Very high0 Ų036.5 Ų36.50%018%0.18CC..Hα-helixtrans-70-3717847.20000112.5S318 L319 Y324 L325 M326 R349 V353 P386S318-T322 WeakPolarHBondContact O-CB 3.43Å; S318-T322 WeakPolarHBondContact O-CG2 3.38Å; S318-T322 PolarHBondContact O-N 2.76Å; S318-T322 PolarHBondContact O-OG1 2.99Å; L319-T322 WeakPolarHBondContact CA-OG1 3.45Å; L319-T322 PolarHBondContact O-N 2.72Å; L319-T322 PolarHBondContact O-OG1 3Å; L319-T322 VanDerWaalsContact O-OG1 3.11Å; T322-Y324 VanDerWaalsContact C-N 3.3Å; T322-Y324 PolarHBondContact O-N 3.25Å; T322-L325 PolarHBondContact O-N 3.11Å; T322-M326 VanDerWaalsContact O-CG 3.26Å; T322-M326 WeakPolarHBondContact O-CG 3.5Å; T322-M326 PolarHBondContact O-N 3.49Å; T322-R349 PolarHBondContact OG1-NH1 2.86Å; T322-R349 PolarHBondContact OG1-NH2 3.22Å; T322-V353 HydrophobicContact CG2-CG2 4.25Å; T322-P386 HydrophobicContact CG2-CB 4.39Å; T322-P386 HydrophobicContact CG2-CG 3.86Å
323A96.2Very high97Very high27 Ų2729.2 Ų29.222%0.22315%0.149CC..Hα-helixtrans-62.4-37.5171.200000112.1F5 L319 N320 F327F5-A323 HydrophobicContact CE2-CB 3.92Å; F5-A323 HydrophobicContact CZ-CB 4.37Å; L319-A323 VanDerWaalsContact O-CB 3.24Å; L319-A323 WeakPolarHBondContact O-CB 3.33Å; L319-A323 PolarHBondContact O-N 2.87Å; N320-A323 PolarHBondContact O-N 2.98Å; A323-F327 VanDerWaalsContact O-CB 3.31Å; A323-F327 WeakPolarHBondContact O-CB 3.34Å; A323-F327 PolarHBondContact O-N 3.03Å
324Y97.4Very high96.7Very high0 Ų026.9 Ų26.90%015%0.151CC..Hα-helixtrans-66.7-44.3173.7-178.2-119000112.3F5 Y11 A12 L15 N320 K321 T322 M326 F327 L328 Y393 I396F5-Y324 HydrophobicContact CB-CD2 4.03Å; F5-Y324 HydrophobicContact CB-CE2 4.38Å; F5-Y324 AromaticContact CD1-CD2 3.58Å; F5-Y324 HydrophobicContact CD1-CD2 3.58Å; F5-Y324 HydrophobicContact CD1-CE2 4.36Å; F5-Y324 HydrophobicContact CD1-CG 4.33Å; F5-Y324 HydrophobicContact CD2-CD2 4.4Å; F5-Y324 HydrophobicContact CE1-CD2 4.07Å; F5-Y324 HydrophobicContact CE1-CG 4.38Å; F5-Y324 AromaticContact CG-CD2 3.77Å; F5-Y324 HydrophobicContact CG-CD2 3.77Å; Y11-Y324 HydrophobicContact CD1-CE2 4.12Å; Y11-Y324 HydrophobicContact CE1-CE2 4.06Å; A12-Y324 HydrophobicContact CB-CE1 4.3Å; L15-Y324 HydrophobicContact CD1-CD1 4.48Å; L15-Y324 HydrophobicContact CD1-CD2 4.05Å; L15-Y324 HydrophobicContact CD1-CE1 4.46Å; L15-Y324 HydrophobicContact CD1-CE2 4.05Å; L15-Y324 HydrophobicContact CD1-CG 4.27Å; N320-Y324 PolarHBondContact O-N 2.89Å; K321-Y324 PolarHBondContact O-N 3.02Å; T322-Y324 VanDerWaalsContact C-N 3.3Å; T322-Y324 PolarHBondContact O-N 3.25Å; Y324-M326 PolarHBondContact O-N 3.33Å; Y324-F327 HydrophobicContact CD2-CD1 4.23Å; Y324-F327 HydrophobicContact CE2-CD1 4.27Å; Y324-F327 PolarHBondContact O-N 3.22Å; Y324-L328 HydrophobicContact CD1-CD1 4.19Å; Y324-L328 HydrophobicContact CD2-CG 4.4Å; Y324-L328 HydrophobicContact CE1-CD1 3.6Å; Y324-L328 HydrophobicContact CE1-CG 4.22Å; Y324-L328 HydrophobicContact CE2-CD1 4.21Å; Y324-L328 HydrophobicContact CE2-CD2 4.08Å; Y324-L328 HydrophobicContact CE2-CG 3.97Å; Y324-L328 WeakPolarHBondContact O-CG 3.32Å; Y324-L328 PolarHBondContact O-N 3.28Å; Y324-Y393 AromaticContact CD1-CD1 3.54Å; Y324-Y393 HydrophobicContact CD1-CD1 3.54Å; Y324-Y393 HydrophobicContact CD1-CE1 4.32Å; Y324-Y393 HydrophobicContact CD1-CG 4.47Å; Y324-Y393 HydrophobicContact CE1-CD1 4.14Å; Y324-Y393 AromaticContact CG-CD1 3.94Å; Y324-Y393 HydrophobicContact CG-CD1 3.94Å; Y324-Y393 HydrophobicContact CG-CE1 4.33Å; Y324-I396 HydrophobicContact CD1-CB 4.2Å; Y324-I396 HydrophobicContact CD1-CG2 3.66Å; Y324-I396 HydrophobicContact CE1-CB 4.45Å; Y324-I396 HydrophobicContact CE1-CG2 4.1Å
325L97.8Very high96.5Very high0 Ų034.1 Ų34.10%019%0.189CC..Hα-helixtrans-56.5-49.7174172.659.1000110.9M37 K321 T322 L328 I329 V353 L384 P386 I396 V400M37-L325 HydrophobicContact CE-CD2 4.29Å; K321-L325 PolarHBondContact O-N 3.18Å; T322-L325 PolarHBondContact O-N 3.11Å; L325-L328 PolarHBondContact O-N 2.87Å; L325-I329 HydrophobicContact CD1-CD1 3.81Å; L325-I329 HydrophobicContact CD1-CG1 4.14Å; L325-I329 HydrophobicContact CG-CD1 3.8Å; L325-I329 VanDerWaalsContact O-CG1 3.29Å; L325-I329 WeakPolarHBondContact O-CG1 3.34Å; L325-I329 PolarHBondContact O-N 2.68Å; L325-V353 HydrophobicContact CD2-CB 4.05Å; L325-V353 HydrophobicContact CD2-CG2 3.92Å; L325-L384 HydrophobicContact CD2-CB 4.03Å; L325-P386 HydrophobicContact CB-CG 4.37Å; L325-P386 HydrophobicContact CD2-CG 3.63Å; L325-I396 HydrophobicContact CB-CG2 3.69Å; L325-I396 HydrophobicContact CD1-CG2 4.02Å; L325-I396 HydrophobicContact CG-CG2 4.43Å; L325-V400 HydrophobicContact CD1-CG2 3.6Å
326M97.1Very high96.5Very high13 Ų1336.7 Ų36.76%0.06420%0.2CC..Hα-helixtrans-64-41.5179.3-66.6177.670.200111.8T322 Y324 L328 I329 D330 Y340 T344 V353T322-M326 VanDerWaalsContact O-CG 3.26Å; T322-M326 WeakPolarHBondContact O-CG 3.5Å; T322-M326 PolarHBondContact O-N 3.49Å; Y324-M326 PolarHBondContact O-N 3.33Å; M326-L328 VanDerWaalsContact C-N 3.32Å; M326-L328 PolarHBondContact O-N 3.03Å; M326-I329 PolarHBondContact O-N 3.24Å; M326-D330 WeakPolarHBondContact O-CB 3.24Å; M326-D330 PolarHBondContact O-N 3.16Å; M326-Y340 VanDerWaalsContact CA-OH 3.3Å; M326-Y340 WeakPolarHBondContact CA-OH 3.41Å; M326-Y340 HydrophobicContact CB-CE1 4.4Å; M326-Y340 WeakPolarHBondContact CB-OH 3.37Å; M326-Y340 HydrophobicContact CE-CD1 4.16Å; M326-Y340 HydrophobicContact CE-CD2 4.47Å; M326-Y340 HydrophobicContact CE-CE1 3.87Å; M326-Y340 HydrophobicContact CE-CE2 4.2Å; M326-Y340 HydrophobicContact CE-CG 4.45Å; M326-Y340 HydrophobicContact CG-CE1 3.93Å; M326-Y340 PolarHBondContact O-OH 3.29Å; M326-T344 HydrophobicContact CE-CG2 3.6Å; M326-V353 HydrophobicContact CG-CG1 4.13Å; M326-V353 HydrophobicContact CG-CG2 3.77Å; M326-V353 HydrophobicContact SD-CG2 4.02Å
327F96.9Very high96.3Very high44 Ų4437.7 Ų37.719%0.19321%0.213CC..Hα-helixtrans-56.6-44.9172.4164.3-93.6000112.3F5 T7 A323 Y324 D330 K331F5-F327 HydrophobicContact CB-CB 4.38Å; F5-F327 HydrophobicContact CB-CD1 3.5Å; F5-F327 VanDerWaalsContact CB-CD1 3.5Å; F5-F327 HydrophobicContact CB-CD2 3.99Å; F5-F327 HydrophobicContact CB-CE1 3.67Å; F5-F327 HydrophobicContact CB-CE2 4.11Å; F5-F327 HydrophobicContact CB-CG 3.67Å; F5-F327 HydrophobicContact CB-CZ 3.96Å; F5-F327 HydrophobicContact CD2-CB 4Å; F5-F327 HydrophobicContact CD2-CG 4.19Å; F5-F327 HydrophobicContact CG-CD1 4.37Å; F5-F327 HydrophobicContact CG-CG 4.35Å; F5-F327 VanDerWaalsContact O-CZ 3.26Å; F5-F327 WeakPolarHBondContact O-CZ 3.37Å; T7-F327 HydrophobicContact CG2-CE1 3.92Å; T7-F327 HydrophobicContact CG2-CZ 4.13Å; A323-F327 VanDerWaalsContact O-CB 3.31Å; A323-F327 WeakPolarHBondContact O-CB 3.34Å; A323-F327 PolarHBondContact O-N 3.03Å; Y324-F327 HydrophobicContact CD2-CD1 4.23Å; Y324-F327 HydrophobicContact CE2-CD1 4.27Å; Y324-F327 PolarHBondContact O-N 3.22Å; F327-D330 PolarHBondContact O-N 2.91Å; F327-K331 HydrophobicContact CD2-CG 4.13Å; F327-K331 HydrophobicContact CE1-CG 4.34Å; F327-K331 HydrophobicContact CE2-CD 4.45Å; F327-K331 HydrophobicContact CE2-CG 3.74Å; F327-K331 HydrophobicContact CZ-CG 3.85Å; F327-K331 WeakPolarHBondContact O-CB 3.44Å; F327-K331 VanDerWaalsContact O-CG 3.28Å; F327-K331 WeakPolarHBondContact O-CG 3.23Å; F327-K331 PolarHBondContact O-N 2.98Å
328L97.8Very high96.3Very high0 Ų038.1 Ų38.10%021%0.214CC..Hα-helixtrans-67.5-40.4178.2-72.2-176.4000111.9T7 Y324 L325 M326 K331 E332 I396 N397 V400T7-L328 HydrophobicContact CG2-CD2 4.15Å; Y324-L328 HydrophobicContact CD1-CD1 4.19Å; Y324-L328 HydrophobicContact CD2-CG 4.4Å; Y324-L328 HydrophobicContact CE1-CD1 3.6Å; Y324-L328 HydrophobicContact CE1-CG 4.22Å; Y324-L328 HydrophobicContact CE2-CD1 4.21Å; Y324-L328 HydrophobicContact CE2-CD2 4.08Å; Y324-L328 HydrophobicContact CE2-CG 3.97Å; Y324-L328 WeakPolarHBondContact O-CG 3.32Å; Y324-L328 PolarHBondContact O-N 3.28Å; L325-L328 PolarHBondContact O-N 2.87Å; M326-L328 VanDerWaalsContact C-N 3.32Å; M326-L328 PolarHBondContact O-N 3.03Å; L328-K331 PolarHBondContact O-N 3.36Å; L328-E332 WeakPolarHBondContact O-CB 3.31Å; L328-E332 WeakPolarHBondContact O-CG 3.16Å; L328-E332 PolarHBondContact O-N 3.35Å; L328-I396 HydrophobicContact CD1-CG2 4.23Å; L328-N397 HydrophobicContact CD1-CB 4.13Å; L328-V400 HydrophobicContact CB-CB 4.16Å; L328-V400 HydrophobicContact CB-CG1 4.01Å; L328-V400 HydrophobicContact CB-CG2 3.79Å; L328-V400 HydrophobicContact CD1-CB 4.4Å; L328-V400 HydrophobicContact CD1-CG2 4.23Å
329I97.2Very high96.2Very high6 Ų640.6 Ų40.63%0.03123%0.231CC..Hα-helixtrans-57.6-50.6173.7-69.5164.2000109.8L325 M326 K331 E332 L333 A334 Y340 V353 L355 V400L325-I329 HydrophobicContact CD1-CD1 3.81Å; L325-I329 HydrophobicContact CD1-CG1 4.14Å; L325-I329 HydrophobicContact CG-CD1 3.8Å; L325-I329 VanDerWaalsContact O-CG1 3.29Å; L325-I329 WeakPolarHBondContact O-CG1 3.34Å; L325-I329 PolarHBondContact O-N 2.68Å; M326-I329 PolarHBondContact O-N 3.24Å; I329-K331 VanDerWaalsContact C-N 3.26Å; I329-K331 PolarHBondContact O-N 3.31Å; I329-E332 PolarHBondContact O-N 2.79Å; I329-L333 HydrophobicContact CB-CD1 4.45Å; I329-L333 HydrophobicContact CG1-CD1 4.08Å; I329-L333 HydrophobicContact CG2-CB 4.34Å; I329-L333 HydrophobicContact CG2-CD1 4.38Å; I329-L333 WeakPolarHBondContact O-CA 3.38Å; I329-L333 VanDerWaalsContact O-CB 3.3Å; I329-L333 WeakPolarHBondContact O-CB 3.27Å; I329-L333 PolarHBondContact O-N 2.67Å; I329-A334 PolarHBondContact O-N 3.07Å; I329-Y340 WeakPolarHBondContact CB-OH 3.2Å; I329-Y340 HydrophobicContact CD1-CE1 4.13Å; I329-Y340 HydrophobicContact CG2-CE1 4.11Å; I329-Y340 WeakPolarHBondContact CG2-OH 3.1Å; I329-V353 HydrophobicContact CD1-CG1 4.2Å; I329-L355 HydrophobicContact CD1-CD1 4.16Å; I329-L355 HydrophobicContact CD1-CD2 4.49Å; I329-L355 HydrophobicContact CG2-CD1 3.75Å; I329-V400 HydrophobicContact CG1-CG2 4.21Å
330D96.4Very high96.2Very high88 Ų8841.1 Ų41.147%0.47123%0.231SC..Hα-helixtrans-61.8-32.4-179.7-66.9-7.2000112.9M326 F327 A334 Y340M326-D330 WeakPolarHBondContact O-CB 3.24Å; M326-D330 PolarHBondContact O-N 3.16Å; F327-D330 PolarHBondContact O-N 2.91Å; D330-A334 WeakPolarHBondContact O-CB 3.38Å; D330-Y340 WeakPolarHBondContact OD1-CE2 3.45Å; D330-Y340 PolarHBondContact OD1-OH 3.44Å
331K96.6Very high96Very high138 Ų13840 Ų4060%0.623%0.226SC*.Hα-helixtrans-88.6-33.5-178.1-68.5-56.6-179.6-167.40114.3T7 F327 L328 I329T7-K331 HydrophobicContact CG2-CB 3.91Å; T7-K331 HydrophobicContact CG2-CG 4.32Å; F327-K331 HydrophobicContact CD2-CG 4.13Å; F327-K331 HydrophobicContact CE1-CG 4.34Å; F327-K331 HydrophobicContact CE2-CD 4.45Å; F327-K331 HydrophobicContact CE2-CG 3.74Å; F327-K331 HydrophobicContact CZ-CG 3.85Å; F327-K331 WeakPolarHBondContact O-CB 3.44Å; F327-K331 VanDerWaalsContact O-CG 3.28Å; F327-K331 WeakPolarHBondContact O-CG 3.23Å; F327-K331 PolarHBondContact O-N 2.98Å; L328-K331 PolarHBondContact O-N 3.36Å; I329-K331 VanDerWaalsContact C-N 3.26Å; I329-K331 PolarHBondContact O-N 3.31Å
332E96.6Very high95.9Very high36 Ų3640.3 Ų40.317%0.16823%0.228CC..Hα-helixtrans-109.6-22.3-169.5-61.8-72.4173.300113.2L328 I329 V400 K404L328-E332 WeakPolarHBondContact O-CB 3.31Å; L328-E332 WeakPolarHBondContact O-CG 3.16Å; L328-E332 PolarHBondContact O-N 3.35Å; I329-E332 PolarHBondContact O-N 2.79Å; E332-V400 HydrophobicContact CB-CG1 3.82Å; E332-V400 HydrophobicContact CG-CG1 4.29Å; E332-K404 HydrophobicContact CB-CD 4.46Å; E332-K404 IonicContact OE2-NZ 2.98Å; E332-K404 PolarHBondContact OE2-NZ 2.93Å
333L96.6Very high95.8Very high0 Ų042 Ų420%024%0.24CC..THydrogen-bonded Turntrans-117-4.4-171.4-56.6-172.9000114.7I329 D335 Y336 Y338 L355 V400 L403 K404I329-L333 HydrophobicContact CB-CD1 4.45Å; I329-L333 HydrophobicContact CG1-CD1 4.08Å; I329-L333 HydrophobicContact CG2-CB 4.34Å; I329-L333 HydrophobicContact CG2-CD1 4.38Å; I329-L333 WeakPolarHBondContact O-CA 3.38Å; I329-L333 VanDerWaalsContact O-CB 3.3Å; I329-L333 WeakPolarHBondContact O-CB 3.27Å; I329-L333 PolarHBondContact O-N 2.67Å; L333-D335 PolarHBondContact O-N 3.45Å; L333-D335 VanDerWaalsContact O-N 3.12Å; L333-Y336 PolarHBondContact O-N 3.4Å; L333-Y338 HydrophobicContact CB-CD2 3.77Å; L333-Y338 HydrophobicContact CB-CE2 4.3Å; L333-Y338 HydrophobicContact CD1-CD2 4.08Å; L333-Y338 HydrophobicContact CD1-CE2 4.06Å; L333-Y338 HydrophobicContact CD2-CE2 4.27Å; L333-Y338 HydrophobicContact CG-CD2 4.37Å; L333-Y338 HydrophobicContact CG-CE2 4.46Å; L333-L355 HydrophobicContact CD1-CD2 4.37Å; L333-V400 HydrophobicContact CD1-CG1 4.14Å; L333-V400 HydrophobicContact CD2-CG1 4.28Å; L333-V400 HydrophobicContact CG-CG1 3.96Å; L333-L403 HydrophobicContact CD1-CB 3.84Å; L333-L403 HydrophobicContact CD1-CD1 3.92Å; L333-L403 HydrophobicContact CD2-CB 4.3Å; L333-K404 HydrophobicContact CD2-CB 3.52Å; L333-K404 HydrophobicContact CD2-CG 4.09Å
334A92.4Very high95.6Very high65 Ų6545.4 Ų45.454%0.53726%0.258SS..THydrogen-bonded Turntrans-55.5-33-174.300000114.4I329 D330 Y336I329-A334 PolarHBondContact O-N 3.07Å; D330-A334 WeakPolarHBondContact O-CB 3.38Å; A334-Y336 VanDerWaalsContact C-N 3.33Å
335D93.3Very high95.5Very high158 Ų15849 Ų4985%0.84528%0.277SS*.THydrogen-bonded Turntrans-88.53.4-178.7-61-39.4000113.7L333L333-D335 PolarHBondContact O-N 3.45Å; L333-D335 VanDerWaalsContact O-N 3.12Å
336Y95.8Very high95.3Very high72 Ų7251.2 Ų51.228%0.28229%0.289SS..THydrogen-bonded Turntrans-111.926.6-172.3-65.8-79.3000113.5L333 A334 Y338 H357 K404 V407 A408L333-Y336 PolarHBondContact O-N 3.4Å; A334-Y336 VanDerWaalsContact C-N 3.33Å; Y336-Y338 WeakPolarHBondContact O-CD2 3.41Å; Y336-Y338 PolarHBondContact O-N 3.22Å; Y336-H357 PolarHBondContact O-CD2 3.34Å; Y336-H357 VanDerWaalsContact O-CD2 3.25Å; Y336-H357 PolarHBondContact O-NE2 2.93Å; Y336-H357 VanDerWaalsContact O-NE2 3.11Å; Y336-K404 HydrophobicContact CE2-CG 3.88Å; Y336-V407 HydrophobicContact CD1-CB 4.26Å; Y336-V407 HydrophobicContact CD1-CG1 3.88Å; Y336-V407 HydrophobicContact CG-CG1 4.34Å; Y336-A408 HydrophobicContact CD1-CB 4.46Å; Y336-A408 HydrophobicContact CE1-CB 3.55Å
337G94.1Very high95.2Very high58 Ų5858.8 Ų58.860%0.59832%0.321SS*.THydrogen-bonded Turntrans73.88.4171.500000115.7
338Y96.3Very high95.1Very high24 Ų2459.4 Ų59.49%0.09433%0.329CS..  trans-80.8140.2177-68.2-74.6000112.3L333 Y336 L355 Q356 H357 I363 L403 V407L333-Y338 HydrophobicContact CB-CD2 3.77Å; L333-Y338 HydrophobicContact CB-CE2 4.3Å; L333-Y338 HydrophobicContact CD1-CD2 4.08Å; L333-Y338 HydrophobicContact CD1-CE2 4.06Å; L333-Y338 HydrophobicContact CD2-CE2 4.27Å; L333-Y338 HydrophobicContact CG-CD2 4.37Å; L333-Y338 HydrophobicContact CG-CE2 4.46Å; Y336-Y338 WeakPolarHBondContact O-CD2 3.41Å; Y336-Y338 PolarHBondContact O-N 3.22Å; Y338-L355 HydrophobicContact CD1-CD1 4.13Å; Y338-L355 HydrophobicContact CD1-CD2 3.43Å; Y338-L355 VanDerWaalsContact CD1-CD2 3.43Å; Y338-L355 HydrophobicContact CD1-CG 3.52Å; Y338-L355 HydrophobicContact CE1-CD2 3.64Å; Y338-L355 HydrophobicContact CE1-CG 4.16Å; Y338-L355 HydrophobicContact CG-CD1 4.28Å; Y338-L355 HydrophobicContact CG-CD2 4.02Å; Y338-L355 HydrophobicContact CG-CG 4.16Å; Y338-Q356 WeakPolarHBondContact CA-O 3.16Å; Y338-H357 HydrophobicContact CD1-CB 3.75Å; Y338-H357 AromaticContact CD1-CD2 3.72Å; Y338-H357 HydrophobicContact CE1-CB 3.85Å; Y338-H357 AromaticContact CE1-CD2 3.78Å; Y338-I363 HydrophobicContact CE1-CD1 4.12Å; Y338-L403 HydrophobicContact CE1-CD2 4.31Å; Y338-L403 WeakPolarHBondContact OH-CD2 3.49Å; Y338-L403 PolarHBondContact OH-O 2.93Å; Y338-V407 HydrophobicContact CE2-CB 4.39Å; Y338-V407 HydrophobicContact CE2-CG2 3.79Å; Y338-V407 WeakPolarHBondContact OH-CG2 3.44Å
339S95.1Very high95.1Very high59 Ų5959.4 Ų59.441%0.41333%0.329SS..EExtended strand (participates in β ladder)trans-133.3167.6170.5590000111.3Q356S339-Q356 PolarHBondContact N-O 3.13Å; S339-Q356 PolarHBondContact O-N 2.92Å; S339-Q356 WeakPolarHBondContact OG-CB 3.44Å; S339-Q356 PolarHBondContact OG-OE1 2.9Å
340Y95.5Very high95Very high47 Ų4759.1 Ų59.118%0.18433%0.327CS..EExtended strand (participates in β ladder)trans-92.9129.3172.9-63.5-69.2000110.7M326 I329 D330 N342 T344 V353 L355M326-Y340 VanDerWaalsContact CA-OH 3.3Å; M326-Y340 WeakPolarHBondContact CA-OH 3.41Å; M326-Y340 HydrophobicContact CB-CE1 4.4Å; M326-Y340 WeakPolarHBondContact CB-OH 3.37Å; M326-Y340 HydrophobicContact CE-CD1 4.16Å; M326-Y340 HydrophobicContact CE-CD2 4.47Å; M326-Y340 HydrophobicContact CE-CE1 3.87Å; M326-Y340 HydrophobicContact CE-CE2 4.2Å; M326-Y340 HydrophobicContact CE-CG 4.45Å; M326-Y340 HydrophobicContact CG-CE1 3.93Å; M326-Y340 PolarHBondContact O-OH 3.29Å; I329-Y340 WeakPolarHBondContact CB-OH 3.2Å; I329-Y340 HydrophobicContact CD1-CE1 4.13Å; I329-Y340 HydrophobicContact CG2-CE1 4.11Å; I329-Y340 WeakPolarHBondContact CG2-OH 3.1Å; D330-Y340 WeakPolarHBondContact OD1-CE2 3.45Å; D330-Y340 PolarHBondContact OD1-OH 3.44Å; Y340-N342 VanDerWaalsContact C-N 3.29Å; Y340-T344 HydrophobicContact CD2-CG2 3.92Å; Y340-T344 HydrophobicContact CE2-CG2 4.28Å; Y340-T344 HydrophobicContact CG-CG2 4.48Å; Y340-V353 HydrophobicContact CD1-CG1 3.9Å; Y340-V353 HydrophobicContact CE1-CG1 3.79Å; Y340-L355 HydrophobicContact CE1-CD1 4.45Å
341G92.6Very high94.9Very high4 Ų455 Ų554%0.04131%0.305CS..SBendtrans-9317.7165.600000113S185 C354S185-G341 WeakPolarHBondContact CA-O 3.01Å; S185-G341 WeakPolarHBondContact CB-O 3.29Å; G341-C354 PolarHBondContact N-O 3.34Å
342N94.8Very high94.9Very high7 Ų748.4 Ų48.44%0.03728%0.277CS..SBendtrans-135.5158.4177.164.2-87000109.9S185 Y340 R349 C354S185-N342 WeakPolarHBondContact O-CA 3.5Å; S185-N342 WeakPolarHBondContact O-CB 3.28Å; Y340-N342 VanDerWaalsContact C-N 3.29Å; N342-R349 WeakPolarHBondContact ND2-CD 3.45Å; N342-C354 HydrophobicContact CB-CB 3.99Å; N342-C354 WeakPolarHBondContact OD1-CA 3.49Å; N342-C354 PolarHBondContact OD1-N 2.94Å; N342-C354 PolarHBondContact OD1-O 2.8Å
343S94.4Very high95Very high37 Ų3746.7 Ų46.726%0.25927%0.269SS..  trans-63143.9171.5178.80000111.3D345 V348 R349S343-D345 VanDerWaalsContact C-N 3.32Å; S343-D345 PolarHBondContact OG-N 3.17Å; S343-D345 VanDerWaalsContact OG-N 3.13Å; S343-V348 WeakPolarHBondContact OG-CG2 3.31Å; S343-R349 WeakPolarHBondContact O-CD 3.18Å
344T92.9Very high95Very high97 Ų9746.7 Ų46.760%0.59527%0.269SS*.SBendtrans-83.7-7.1172.259.30000113.2M326 Y340M326-T344 HydrophobicContact CE-CG2 3.6Å; Y340-T344 HydrophobicContact CD2-CG2 3.92Å; Y340-T344 HydrophobicContact CE2-CG2 4.28Å; Y340-T344 HydrophobicContact CG-CG2 4.48Å
345D95Very high95.2Very high76 Ų7643.6 Ų43.641%0.40624%0.243SC..  trans-82.1117174.9-176.2-7.8000111.1S343 K347 V348 R349S343-D345 VanDerWaalsContact C-N 3.32Å; S343-D345 PolarHBondContact OG-N 3.17Å; S343-D345 VanDerWaalsContact OG-N 3.13Å; D345-K347 PolarHBondContact O-N 2.91Å; D345-K347 VanDerWaalsContact O-N 3.08Å; D345-K347 WeakPolarHBondContact OD1-CB 3.17Å; D345-K347 PolarHBondContact OD1-N 3.21Å; D345-V348 HydrophobicContact CB-CG2 3.95Å; D345-V348 PolarHBondContact O-N 3.23Å; D345-V348 VanDerWaalsContact O-N 3.13Å; D345-R349 PolarHBondContact O-N 2.96Å
346D93.6Very high95.3Very high47 Ų4736.9 Ų36.925%0.25121%0.207SC..THydrogen-bonded Turntrans-54-25.5177.9-77.3-19.2000114.4R315 L319 V348 R349R315-D346 PolarHBondContact NH2-O 3.13Å; L319-D346 HydrophobicContact CD1-CB 4.49Å; L319-D346 HydrophobicContact CD2-CB 3.67Å; D346-V348 VanDerWaalsContact C-N 3.34Å; D346-R349 IonicContact OD1-CZ 2.67Å; D346-R349 IonicContact OD1-NE 3.92Å; D346-R349 IonicContact OD1-NH2 2.8Å; D346-R349 PolarHBondContact OD1-NH2 3.09Å
347K94.3Very high95.2Very high171 Ų17133.9 Ų33.974%0.74320%0.195SC*.THydrogen-bonded Turntrans-72.5-27.8-179.1-66.1178.2-176.6174.20113.2D345D345-K347 PolarHBondContact O-N 2.91Å; D345-K347 VanDerWaalsContact O-N 3.08Å; D345-K347 WeakPolarHBondContact OD1-CB 3.17Å; D345-K347 PolarHBondContact OD1-N 3.21Å
348V95.8Very high95Very high58 Ų5839 Ų3935%0.35220%0.204SC..SBendtrans-118.512.7-174.1-62.60000112.6Q187 I188 S343 D345 D346Q187-V348 CarbonylContact C-O 3.26Å; Q187-V348 WeakPolarHBondContact CA-O 3.32Å; I188-V348 PolarHBondContact N-O 2.9Å; S343-V348 WeakPolarHBondContact OG-CG2 3.31Å; D345-V348 HydrophobicContact CB-CG2 3.95Å; D345-V348 PolarHBondContact O-N 3.23Å; D345-V348 VanDerWaalsContact O-N 3.13Å; D346-V348 VanDerWaalsContact C-N 3.34Å
349R96.7Very high94.8Very high0 Ų040 Ų400%021%0.209CC..BIsolated β-bridgetrans-118.3130.9178.2-178-174.559.383.30.9111.4A186 I188 R315 T322 N342 S343 D345 D346A186-R349 HydrophobicContact CB-CG 4.18Å; A186-R349 CarbonylContact O-C 3.26Å; A186-R349 WeakPolarHBondContact O-CA 3.36Å; I188-R349 VanDerWaalsContact CD1-C 3.44Å; I188-R349 VanDerWaalsContact CD1-O 3.25Å; I188-R349 WeakPolarHBondContact CD1-O 3.3Å; R315-R349 PolarHBondContact NH1-O 3.39Å; R315-R349 PolarHBondContact NH2-O 2.84Å; T322-R349 PolarHBondContact OG1-NH1 2.86Å; T322-R349 PolarHBondContact OG1-NH2 3.22Å; N342-R349 WeakPolarHBondContact ND2-CD 3.45Å; S343-R349 WeakPolarHBondContact O-CD 3.18Å; D345-R349 PolarHBondContact O-N 2.96Å; D346-R349 IonicContact OD1-CZ 2.67Å; D346-R349 IonicContact OD1-NE 3.92Å; D346-R349 IonicContact OD1-NH2 2.8Å; D346-R349 PolarHBondContact OD1-NH2 3.09Å
350G96.4Very high94.5Very high0 Ų037.1 Ų37.10%019%0.189CC..  trans-69.5-147.917900000114.1A186 R315A186-G350 PolarHBondContact O-N 3.24Å; R315-G350 PolarHBondContact NH1-O 3.41Å
351G94.1Very high93.9Very high0 Ų037.3 Ų37.30%019%0.19CC..SBendtrans-89.82.9-173.100000115.9Y235Y235-G351 WeakPolarHBondContact OH-CA 3.43Å
352H96.6Very high93.5Very high0 Ų038.1 Ų38.10%019%0.192CC..SBendtrans-133.3165.8-178.162.9-90.1000111.8Y183 Y235 C354 L384 A385Y183-H352 PolarHBondContact O-NE2 3.44Å; Y235-H352 PolarHBondContact OH-ND1 2.68Å; H352-C354 PolarHBondContact CD2-SG 3.4Å; H352-L384 WeakPolarHBondContact CA-O 3.4Å; H352-L384 WeakPolarHBondContact CB-O 3.39Å; H352-A385 HydrophobicContact CB-CB 3.67Å
353V97.6Very high93.5Very high0 Ų037.8 Ų37.80%019%0.19CC..EExtended strand (participates in β ladder)trans-112.3135.2174.6177.10000107.9T322 L325 M326 I329 Y340 R383 L384T322-V353 HydrophobicContact CG2-CG2 4.25Å; L325-V353 HydrophobicContact CD2-CB 4.05Å; L325-V353 HydrophobicContact CD2-CG2 3.92Å; M326-V353 HydrophobicContact CG-CG1 4.13Å; M326-V353 HydrophobicContact CG-CG2 3.77Å; M326-V353 HydrophobicContact SD-CG2 4.02Å; I329-V353 HydrophobicContact CD1-CG1 4.2Å; Y340-V353 HydrophobicContact CD1-CG1 3.9Å; Y340-V353 HydrophobicContact CE1-CG1 3.79Å; V353-R383 WeakPolarHBondContact O-CA 3.49Å; V353-L384 PolarHBondContact N-O 3.43Å; V353-L384 PolarHBondContact O-N 3.03Å
354C96.6Very high93.4Very high0 Ų036 Ų360%018%0.177CC..EExtended strand (participates in β ladder)trans-108.795.3-176.7-56.30000108.3R184 G341 N342 H352 V381R184-C354 PolarHBondContact O-SG 2.85Å; G341-C354 PolarHBondContact N-O 3.34Å; N342-C354 HydrophobicContact CB-CB 3.99Å; N342-C354 WeakPolarHBondContact OD1-CA 3.49Å; N342-C354 PolarHBondContact OD1-N 2.94Å; N342-C354 PolarHBondContact OD1-O 2.8Å; H352-C354 PolarHBondContact CD2-SG 3.4Å; C354-V381 HydrophobicContact CB-CG1 3.71Å
355L96.6Very high92.9Very high1 Ų131.9 Ų31.91%0.00515%0.153CC..EExtended strand (participates in β ladder)trans-90.7118.4-178.2-165.965.5000109.5I329 L333 Y338 Y340 I382 L403I329-L355 HydrophobicContact CD1-CD1 4.16Å; I329-L355 HydrophobicContact CD1-CD2 4.49Å; I329-L355 HydrophobicContact CG2-CD1 3.75Å; L333-L355 HydrophobicContact CD1-CD2 4.37Å; Y338-L355 HydrophobicContact CD1-CD1 4.13Å; Y338-L355 HydrophobicContact CD1-CD2 3.43Å; Y338-L355 VanDerWaalsContact CD1-CD2 3.43Å; Y338-L355 HydrophobicContact CD1-CG 3.52Å; Y338-L355 HydrophobicContact CE1-CD2 3.64Å; Y338-L355 HydrophobicContact CE1-CG 4.16Å; Y338-L355 HydrophobicContact CG-CD1 4.28Å; Y338-L355 HydrophobicContact CG-CD2 4.02Å; Y338-L355 HydrophobicContact CG-CG 4.16Å; Y340-L355 HydrophobicContact CE1-CD1 4.45Å; L355-I382 PolarHBondContact N-O 2.94Å; L355-I382 PolarHBondContact O-N 3.39Å; L355-L403 HydrophobicContact CD2-CD1 3.93Å; L355-L403 HydrophobicContact CD2-CD2 4.41Å
356Q95.5Very high92.8Very high16 Ų1628.2 Ų28.28%0.07513%0.134CC..EExtended strand (participates in β ladder)trans-91.6141.5178.2-75.4176.9-20.100111.3E158 Y338 S339 N380 V381E158-Q356 PolarHBondContact OE1-NE2 3.39Å; Y338-Q356 WeakPolarHBondContact CA-O 3.16Å; S339-Q356 PolarHBondContact N-O 3.13Å; S339-Q356 PolarHBondContact O-N 2.92Å; S339-Q356 WeakPolarHBondContact OG-CB 3.44Å; S339-Q356 PolarHBondContact OG-OE1 2.9Å; Q356-N380 VanDerWaalsContact CA-O 3.24Å; Q356-N380 WeakPolarHBondContact CA-O 3.48Å; Q356-V381 HydrophobicContact CG-CG2 3.95Å
357H94.9Very high92.9Very high9 Ų926 Ų264%0.04212%0.122CC..  trans-160.3143.7171.3-169-75.9000109.5Y336 Y338 E359 A360 I363 N380Y336-H357 PolarHBondContact O-CD2 3.34Å; Y336-H357 VanDerWaalsContact O-CD2 3.25Å; Y336-H357 PolarHBondContact O-NE2 2.93Å; Y336-H357 VanDerWaalsContact O-NE2 3.11Å; Y338-H357 HydrophobicContact CD1-CB 3.75Å; Y338-H357 AromaticContact CD1-CD2 3.72Å; Y338-H357 HydrophobicContact CE1-CB 3.85Å; Y338-H357 AromaticContact CE1-CD2 3.78Å; H357-E359 WeakPolarHBondContact ND1-CB 3.48Å; H357-E359 PolarHBondContact ND1-N 3.35Å; H357-E359 PolarHBondContact O-N 3.17Å; H357-A360 HydrophobicContact CB-CB 4.33Å; H357-A360 WeakPolarHBondContact O-CB 3.31Å; H357-A360 PolarHBondContact O-N 3.25Å; H357-I363 HydrophobicContact CB-CD1 3.94Å; H357-I363 VanDerWaalsContact CG-CD1 3.42Å; H357-I363 VanDerWaalsContact ND1-CD1 3.28Å; H357-I363 WeakPolarHBondContact ND1-CD1 3.14Å; H357-N380 PolarHBondContact N-O 3.39Å; H357-N380 WeakPolarHBondContact O-CB 3.28Å
358E90.3Very high92.7Very high166 Ų16622.7 Ų22.778%0.77610%0.104SC*.THydrogen-bonded Turntrans-56.2-41179.975.6-168.6163.600112.1A360E358-A360 VanDerWaalsContact C-N 3.32Å; E358-A360 PolarHBondContact O-N 3.27Å
359E90.9Very high92.3Very high44 Ų4425.6 Ų25.621%0.20612%0.118CC..THydrogen-bonded Turntrans-84.916.8174.6-58.1-71.3-174.700115.3H357 Y361 R362 I363 Y412H357-E359 WeakPolarHBondContact ND1-CB 3.48Å; H357-E359 PolarHBondContact ND1-N 3.35Å; H357-E359 PolarHBondContact O-N 3.17Å; E359-Y361 PolarHBondContact O-N 2.95Å; E359-Y361 VanDerWaalsContact O-N 3.08Å; E359-R362 PolarHBondContact O-N 3.41Å; E359-R362 IonicContact OE1-CZ 3.03Å; E359-R362 IonicContact OE1-NH1 2.84Å; E359-R362 PolarHBondContact OE1-NH1 2.87Å; E359-R362 WeakPolarHBondContact OE2-CD 3.44Å; E359-R362 IonicContact OE2-CZ 3.71Å; E359-R362 IonicContact OE2-NE 3Å; E359-R362 PolarHBondContact OE2-NE 3.39Å; E359-R362 IonicContact OE2-NH1 3.09Å; E359-R362 PolarHBondContact OE2-NH1 3.21Å; E359-R362 IonicContact OE2-NH2 3.56Å; E359-I363 HydrophobicContact CB-CD1 3.91Å; E359-I363 HydrophobicContact CB-CG1 4.1Å; E359-I363 WeakPolarHBondContact O-CG1 2.98Å; E359-I363 PolarHBondContact O-N 3.07Å; E359-Y412 HydrophobicContact CB-CD2 3.72Å; E359-Y412 HydrophobicContact CB-CE2 3.96Å; E359-Y412 HydrophobicContact CB-CG 4.35Å; E359-Y412 HydrophobicContact CG-CD2 3.64Å; E359-Y412 HydrophobicContact CG-CE2 3.36Å
360A90.1Very high92.2Very high0 Ų028.7 Ų28.70%014%0.135CC..Hα-helixtrans-53.6-36.9-169.800000114.3H357 E358 A364 F376 N380 I382H357-A360 HydrophobicContact CB-CB 4.33Å; H357-A360 WeakPolarHBondContact O-CB 3.31Å; H357-A360 PolarHBondContact O-N 3.25Å; E358-A360 VanDerWaalsContact C-N 3.32Å; E358-A360 PolarHBondContact O-N 3.27Å; A360-A364 VanDerWaalsContact O-CB 3.23Å; A360-A364 WeakPolarHBondContact O-CB 3.41Å; A360-A364 PolarHBondContact O-N 2.67Å; A360-F376 HydrophobicContact CB-CD2 4.25Å; A360-F376 HydrophobicContact CB-CE2 3.84Å; A360-N380 WeakPolarHBondContact CB-O 3.42Å; A360-I382 HydrophobicContact CB-CD1 4.24Å; A360-I382 HydrophobicContact CB-CG1 3.75Å
361Y82.2Confident92Very high50 Ų5029.9 Ų29.920%0.19615%0.147CC..Hα-helixtrans-61.2-50.1175.5174.2-91.6000111.6E359 A364 A365 F376 R419 A481E359-Y361 PolarHBondContact O-N 2.95Å; E359-Y361 VanDerWaalsContact O-N 3.08Å; Y361-A364 PolarHBondContact O-N 3.14Å; Y361-A365 PolarHBondContact O-N 3.17Å; Y361-F376 AromaticContact CD2-CD1 3.93Å; Y361-F376 HydrophobicContact CD2-CD1 3.93Å; Y361-F376 AromaticContact CD2-CE1 3.79Å; Y361-F376 HydrophobicContact CD2-CE1 3.79Å; Y361-F376 HydrophobicContact CD2-CZ 4.27Å; Y361-F376 HydrophobicContact CG-CE1 4.43Å; Y361-F376 HydrophobicContact CG-CZ 4.48Å; Y361-F376 VanDerWaalsContact N-CE2 3.34Å; Y361-R419 PolarHBondContact OH-NH1 3.15Å; Y361-R419 PolarHBondContact OH-NH2 2.82Å; Y361-A481 HydrophobicContact CD2-CB 4.32Å; Y361-A481 HydrophobicContact CE2-CB 4.3Å
362R84.6Confident92.2Very high21 Ų2129.9 Ų29.98%0.07915%0.147CC..Hα-helixtrans-69-37.2-178-70.2171.742-157.6-2.7111E359 A365 A366 Y412 E413 Y415E359-R362 PolarHBondContact O-N 3.41Å; E359-R362 IonicContact OE1-CZ 3.03Å; E359-R362 IonicContact OE1-NH1 2.84Å; E359-R362 PolarHBondContact OE1-NH1 2.87Å; E359-R362 WeakPolarHBondContact OE2-CD 3.44Å; E359-R362 IonicContact OE2-CZ 3.71Å; E359-R362 IonicContact OE2-NE 3Å; E359-R362 PolarHBondContact OE2-NE 3.39Å; E359-R362 IonicContact OE2-NH1 3.09Å; E359-R362 PolarHBondContact OE2-NH1 3.21Å; E359-R362 IonicContact OE2-NH2 3.56Å; R362-A365 PolarHBondContact O-N 3.32Å; R362-A366 WeakPolarHBondContact O-CB 3.28Å; R362-A366 PolarHBondContact O-N 3.39Å; R362-Y412 HydrophobicContact CB-CD2 4.43Å; R362-Y412 VanDerWaalsContact CZ-CD2 3.5Å; R362-Y412 PolarHBondContact NE-O 3.06Å; R362-Y412 VanDerWaalsContact NH2-C 3.3Å; R362-Y412 VanDerWaalsContact NH2-CE2 3.29Å; R362-Y412 PolarHBondContact NH2-O 2.93Å; R362-Y412 VanDerWaalsContact NH2-O 3.13Å; R362-E413 VanDerWaalsContact NH2-N 3.15Å; R362-Y415 WeakPolarHBondContact CD-O 3.43Å; R362-Y415 WeakPolarHBondContact CG-O 3.33Å; R362-Y415 PolarHBondContact NE-O 3.3Å; R362-Y415 VanDerWaalsContact NE-O 3.07Å
363I95.1Very high92.1Very high0 Ų031.3 Ų31.30%016%0.156CC..Hα-helixtrans-63.7-45.5172.2-65.7166.3000110.7Y338 H357 E359 A365 A366 L367 I382 L403 I406 V407 Y412Y338-I363 HydrophobicContact CE1-CD1 4.12Å; H357-I363 HydrophobicContact CB-CD1 3.94Å; H357-I363 VanDerWaalsContact CG-CD1 3.42Å; H357-I363 VanDerWaalsContact ND1-CD1 3.28Å; H357-I363 WeakPolarHBondContact ND1-CD1 3.14Å; E359-I363 HydrophobicContact CB-CD1 3.91Å; E359-I363 HydrophobicContact CB-CG1 4.1Å; E359-I363 WeakPolarHBondContact O-CG1 2.98Å; E359-I363 PolarHBondContact O-N 3.07Å; I363-A365 VanDerWaalsContact C-N 3.29Å; I363-A365 PolarHBondContact O-N 2.85Å; I363-A366 PolarHBondContact O-N 3.24Å; I363-L367 HydrophobicContact CG2-CD1 4.46Å; I363-L367 WeakPolarHBondContact O-CG 3.39Å; I363-L367 PolarHBondContact O-N 3.07Å; I363-I382 HydrophobicContact CB-CD1 3.85Å; I363-I382 HydrophobicContact CG2-CD1 3.47Å; I363-I382 VanDerWaalsContact CG2-CD1 3.47Å; I363-L403 HydrophobicContact CG2-CD2 3.82Å; I363-I406 HydrophobicContact CB-CG2 4.37Å; I363-I406 HydrophobicContact CG1-CG2 4.12Å; I363-I406 HydrophobicContact CG2-CG2 4.17Å; I363-V407 HydrophobicContact CD1-CG2 3.62Å; I363-V407 HydrophobicContact CG1-CG2 4.06Å; I363-Y412 HydrophobicContact CG1-CD1 4.34Å; I363-Y412 HydrophobicContact CG1-CG 4.2Å
364A91.6Very high92Very high0 Ų031.5 Ų31.50%016%0.157CC..Hα-helixtrans-62.8-36.1176.600000112.3A360 Y361 R368 P374 F376 I382A360-A364 VanDerWaalsContact O-CB 3.23Å; A360-A364 WeakPolarHBondContact O-CB 3.41Å; A360-A364 PolarHBondContact O-N 2.67Å; Y361-A364 PolarHBondContact O-N 3.14Å; A364-R368 PolarHBondContact O-N 3.33Å; A364-P374 HydrophobicContact CB-CG 4.12Å; A364-F376 HydrophobicContact CB-CB 4.1Å; A364-F376 HydrophobicContact CB-CD2 4.49Å; A364-I382 HydrophobicContact CB-CG1 4.41Å
365A83.1Confident91.9Very high10 Ų1032.2 Ų32.28%0.08316%0.161CC..Hα-helixtrans-66.2-43.5172.600000112Y361 R362 I363 L367 R368 N369 Y415Y361-A365 PolarHBondContact O-N 3.17Å; R362-A365 PolarHBondContact O-N 3.32Å; I363-A365 VanDerWaalsContact C-N 3.29Å; I363-A365 PolarHBondContact O-N 2.85Å; A365-L367 VanDerWaalsContact C-N 3.34Å; A365-L367 PolarHBondContact O-N 3.2Å; A365-R368 PolarHBondContact O-N 3.4Å; A365-N369 PolarHBondContact O-N 2.99Å; A365-Y415 HydrophobicContact CB-CD1 3.5Å; A365-Y415 VanDerWaalsContact CB-CD1 3.5Å; A365-Y415 HydrophobicContact CB-CE1 3.8Å; A365-Y415 HydrophobicContact CB-CG 4.14Å
366A91.5Very high91.5Very high0 Ų033.6 Ų33.60%017%0.166CC..Hα-helixtrans-63.7-37.4175.200000112.7R362 I363 N369 N370 I406 I411 Y415R362-A366 WeakPolarHBondContact O-CB 3.28Å; R362-A366 PolarHBondContact O-N 3.39Å; I363-A366 PolarHBondContact O-N 3.24Å; A366-N369 PolarHBondContact O-N 2.96Å; A366-N370 PolarHBondContact O-N 3.35Å; A366-N370 VanDerWaalsContact O-N 3.07Å; A366-N370 PolarHBondContact O-ND2 2.82Å; A366-I406 HydrophobicContact CB-CB 4.47Å; A366-I406 HydrophobicContact CB-CD1 3.73Å; A366-I406 HydrophobicContact CB-CG1 3.9Å; A366-I406 HydrophobicContact CB-CG2 3.7Å; A366-I411 HydrophobicContact CB-CG2 4.27Å; A366-Y415 WeakPolarHBondContact CA-OH 3.45Å; A366-Y415 HydrophobicContact CB-CD2 4.3Å; A366-Y415 HydrophobicContact CB-CE2 3.61Å
367L96.3Very high90.9Very high0 Ų035.1 Ų35.10%017%0.172CC..Hα-helixtrans-58.6-48.7173.5-80.4174000111.6I363 A365 N369 N370 G371 V372 P374 I382 T402 L403 I406I363-L367 HydrophobicContact CG2-CD1 4.46Å; I363-L367 WeakPolarHBondContact O-CG 3.39Å; I363-L367 PolarHBondContact O-N 3.07Å; A365-L367 VanDerWaalsContact C-N 3.34Å; A365-L367 PolarHBondContact O-N 3.2Å; L367-N369 VanDerWaalsContact C-N 3.32Å; L367-N369 PolarHBondContact O-N 3.21Å; L367-N370 CarbonylContact O-C 3.4Å; L367-N370 VanDerWaalsContact O-C 3.3Å; L367-N370 WeakPolarHBondContact O-CA 3.11Å; L367-N370 PolarHBondContact O-N 3.03Å; L367-G371 PolarHBondContact O-N 3.07Å; L367-V372 CarbonylContact C-O 3.6Å; L367-V372 HydrophobicContact CB-CB 4.13Å; L367-V372 HydrophobicContact CB-CG1 4.46Å; L367-V372 HydrophobicContact CD2-CB 4.02Å; L367-V372 HydrophobicContact CD2-CG1 4.15Å; L367-V372 HydrophobicContact CD2-CG2 4.22Å; L367-V372 PolarHBondContact O-N 2.99Å; L367-P374 HydrophobicContact CB-CG 4.04Å; L367-P374 HydrophobicContact CD1-CB 4.14Å; L367-P374 HydrophobicContact CD1-CG 3.91Å; L367-I382 HydrophobicContact CD1-CG2 4.21Å; L367-T402 HydrophobicContact CD2-CG2 3.85Å; L367-L403 HydrophobicContact CD1-CD2 3.74Å; L367-L403 HydrophobicContact CD1-CG 4.45Å; L367-L403 HydrophobicContact CD2-CD2 4.08Å; L367-L403 HydrophobicContact CD2-CG 4.1Å; L367-L403 HydrophobicContact CG-CD2 4.21Å; L367-I406 HydrophobicContact CB-CD1 4.36Å; L367-I406 HydrophobicContact CD2-CD1 3.71Å; L367-I406 HydrophobicContact CG-CD1 3.78Å
368R90.4Very high89.7Confident101 Ų10138.4 Ų38.438%0.38119%0.187SC..Hα-helixtrans-57.6-44.2177.2-73.8-173.8-71.2-89.7-0.3112.2A364 A365 N370 G371 V372A364-R368 PolarHBondContact O-N 3.33Å; A365-R368 PolarHBondContact O-N 3.4Å; R368-N370 PolarHBondContact O-N 3.14Å; R368-G371 PolarHBondContact O-N 3.24Å; R368-G371 VanDerWaalsContact O-N 3.07Å; R368-V372 WeakPolarHBondContact CA-O 3.44Å; R368-V372 PolarHBondContact N-O 3.31Å
369N88.3Confident88.8Confident120 Ų12034.3 Ų34.364%0.64218%0.175SC*.Hα-helixtrans-68-18.3176.7-79.23.3000113.6A365 A366 L367 Y415A365-N369 PolarHBondContact O-N 2.99Å; A366-N369 PolarHBondContact O-N 2.96Å; L367-N369 VanDerWaalsContact C-N 3.32Å; L367-N369 PolarHBondContact O-N 3.21Å; N369-Y415 VanDerWaalsContact CB-OH 3.28Å; N369-Y415 WeakPolarHBondContact CB-OH 3.41Å; N369-Y415 WeakPolarHBondContact ND2-CE1 3.47Å; N369-Y415 PolarHBondContact ND2-OH 3.46Å
370N92.8Very high88.7Confident65 Ų6534.3 Ų34.335%0.34818%0.176SC..THydrogen-bonded Turntrans-100.722172.9-73.8-92.7000112.5A366 L367 R368 V372 T402A366-N370 PolarHBondContact O-N 3.35Å; A366-N370 VanDerWaalsContact O-N 3.07Å; A366-N370 PolarHBondContact O-ND2 2.82Å; L367-N370 CarbonylContact O-C 3.4Å; L367-N370 VanDerWaalsContact O-C 3.3Å; L367-N370 WeakPolarHBondContact O-CA 3.11Å; L367-N370 PolarHBondContact O-N 3.03Å; R368-N370 PolarHBondContact O-N 3.14Å; N370-V372 VanDerWaalsContact C-N 3.33Å; N370-V372 PolarHBondContact O-N 3.47Å; N370-T402 HydrophobicContact CB-CG2 3.69Å
371G93.1Very high88.8Confident24 Ų2434.3 Ų34.325%0.24718%0.176CC..THydrogen-bonded Turntrans77.99.9172.900000115.2E34 I35 L367 R368E34-G371 CarbonylContact C-O 3.52Å; E34-G371 WeakPolarHBondContact CA-O 3.47Å; I35-G371 PolarHBondContact N-O 3.08Å; L367-G371 PolarHBondContact O-N 3.07Å; R368-G371 PolarHBondContact O-N 3.24Å; R368-G371 VanDerWaalsContact O-N 3.07Å
372V97.6Very high89.5Confident0 Ų032 Ų320%017%0.167CC..EExtended strand (participates in β ladder)trans-101.4128.4174.8-179.80000109.1I35 M37 L367 R368 N370 P374 V399 T402I35-V372 HydrophobicContact CB-CG2 4.32Å; I35-V372 HydrophobicContact CD1-CG2 4.38Å; I35-V372 WeakPolarHBondContact O-CA 3.45Å; M37-V372 HydrophobicContact CG-CG1 4.3Å; L367-V372 CarbonylContact C-O 3.6Å; L367-V372 HydrophobicContact CB-CB 4.13Å; L367-V372 HydrophobicContact CB-CG1 4.46Å; L367-V372 HydrophobicContact CD2-CB 4.02Å; L367-V372 HydrophobicContact CD2-CG1 4.15Å; L367-V372 HydrophobicContact CD2-CG2 4.22Å; L367-V372 PolarHBondContact O-N 2.99Å; R368-V372 WeakPolarHBondContact CA-O 3.44Å; R368-V372 PolarHBondContact N-O 3.31Å; N370-V372 VanDerWaalsContact C-N 3.33Å; N370-V372 PolarHBondContact O-N 3.47Å; V372-P374 WeakPolarHBondContact O-CD 3.42Å; V372-V399 HydrophobicContact CG1-CG1 4.4Å; V372-V399 HydrophobicContact CG1-CG2 3.87Å; V372-V399 HydrophobicContact CG2-CG2 4.16Å; V372-T402 HydrophobicContact CG2-CG2 4.41Å
373V96.1Very high90.1Very high31 Ų3131 Ų3119%0.18816%0.163CC..EExtended strand (participates in β ladder)trans-101.694176.9-175.10000109.8E34 I35 Y36 M37 D38E34-V373 HydrophobicContact CG-CG2 3.75Å; I35-V373 PolarHBondContact O-N 3.37Å; Y36-V373 HydrophobicContact CD2-CB 3.89Å; Y36-V373 HydrophobicContact CD2-CG1 4.04Å; Y36-V373 HydrophobicContact CD2-CG2 4.16Å; Y36-V373 HydrophobicContact CE2-CB 4.21Å; Y36-V373 HydrophobicContact CE2-CG1 3.82Å; M37-V373 CarbonylContact C-O 3.6Å; M37-V373 WeakPolarHBondContact CA-O 3.49Å; M37-V373 WeakPolarHBondContact CB-O 3.23Å; M37-V373 PolarHBondContact N-O 3.21Å; D38-V373 HydrophobicContact CB-CG1 4.19Å; D38-V373 PolarHBondContact N-O 3.23Å
374P95.6Very high90.3Very high4 Ų431 Ų313%0.02616%0.163CC..  trans-91.1173.6170.239.9-38.6000110.9A364 L367 V372 I382 L384A364-P374 HydrophobicContact CB-CG 4.12Å; L367-P374 HydrophobicContact CB-CG 4.04Å; L367-P374 HydrophobicContact CD1-CB 4.14Å; L367-P374 HydrophobicContact CD1-CG 3.91Å; V372-P374 WeakPolarHBondContact O-CD 3.42Å; P374-I382 HydrophobicContact CB-CG2 3.73Å; P374-I382 HydrophobicContact CG-CG2 4.43Å; P374-L384 HydrophobicContact CB-CD2 3.87Å
375D92.8Very high90.5Very high15 Ų1531 Ų318%0.0816%0.163CC..EExtended strand (participates in β ladder)trans-109.7143.7161.6178.174.5000111.3D38 R377 I382 R383D38-D375 WeakPolarHBondContact OD1-CB 3.35Å; D375-R377 IonicContact OD1-CZ 2.83Å; D375-R377 VanDerWaalsContact OD1-CZ 3.25Å; D375-R377 IonicContact OD1-NH1 2.75Å; D375-R377 PolarHBondContact OD1-NH1 2.81Å; D375-R377 IonicContact OD1-NH2 3.7Å; D375-R377 PolarHBondContact OD1-NH2 3.18Å; D375-R377 IonicContact OD2-CZ 2.81Å; D375-R377 IonicContact OD2-NE 3.72Å; D375-R377 PolarHBondContact OD2-NE 3.42Å; D375-R377 IonicContact OD2-NH1 3.53Å; D375-R377 PolarHBondContact OD2-NH1 2.84Å; D375-R377 IonicContact OD2-NH2 3.66Å; D375-R377 PolarHBondContact OD2-NH2 2.6Å; D375-I382 CarbonylContact O-C 3.57Å; D375-I382 WeakPolarHBondContact O-CA 3.05Å; D375-R383 HydrophobicContact CB-CB 4.28Å; D375-R383 PolarHBondContact N-O 2.84Å; D375-R383 VanDerWaalsContact N-O 3.14Å; D375-R383 PolarHBondContact O-N 2.87Å; D375-R383 IonicContact OD1-NH2 3.2Å; D375-R383 IonicContact OD2-CZ 2.73Å; D375-R383 IonicContact OD2-NE 3.59Å; D375-R383 PolarHBondContact OD2-NE 2.96Å; D375-R383 IonicContact OD2-NH2 2.85Å; D375-R383 PolarHBondContact OD2-NH2 3.18Å
376F88.4Confident91.2Very high29 Ų2930.5 Ų30.513%0.12716%0.159CC..EExtended strand (participates in β ladder)trans-113138.7179.3171.5-102.2000110.3A360 Y361 A364 E378 V381A360-F376 HydrophobicContact CB-CD2 4.25Å; A360-F376 HydrophobicContact CB-CE2 3.84Å; Y361-F376 AromaticContact CD2-CD1 3.93Å; Y361-F376 HydrophobicContact CD2-CD1 3.93Å; Y361-F376 AromaticContact CD2-CE1 3.79Å; Y361-F376 HydrophobicContact CD2-CE1 3.79Å; Y361-F376 HydrophobicContact CD2-CZ 4.27Å; Y361-F376 HydrophobicContact CG-CE1 4.43Å; Y361-F376 HydrophobicContact CG-CZ 4.48Å; Y361-F376 VanDerWaalsContact N-CE2 3.34Å; A364-F376 HydrophobicContact CB-CB 4.1Å; A364-F376 HydrophobicContact CB-CD2 4.49Å; F376-E378 HydrophobicContact CE1-CG 4.07Å; F376-E378 WeakPolarHBondContact CE1-OE1 3.18Å; F376-V381 CarbonylContact C-O 3.57Å; F376-V381 WeakPolarHBondContact CA-O 3.47Å; F376-V381 VanDerWaalsContact CD2-O 3.28Å; F376-V381 WeakPolarHBondContact CD2-O 3.17Å
377R84.4Confident91.5Very high49 Ų4931 Ų3119%0.18516%0.162CC..EExtended strand (participates in β ladder)trans-132.4128.8174.6-67.7-60.6-178.4-100.9-4.1110.4Y183 D375 N380 V381 R383Y183-R377 HydrophobicContact CE2-CG 4.26Å; D375-R377 IonicContact OD1-CZ 2.83Å; D375-R377 VanDerWaalsContact OD1-CZ 3.25Å; D375-R377 IonicContact OD1-NH1 2.75Å; D375-R377 PolarHBondContact OD1-NH1 2.81Å; D375-R377 IonicContact OD1-NH2 3.7Å; D375-R377 PolarHBondContact OD1-NH2 3.18Å; D375-R377 IonicContact OD2-CZ 2.81Å; D375-R377 IonicContact OD2-NE 3.72Å; D375-R377 PolarHBondContact OD2-NE 3.42Å; D375-R377 IonicContact OD2-NH1 3.53Å; D375-R377 PolarHBondContact OD2-NH1 2.84Å; D375-R377 IonicContact OD2-NH2 3.66Å; D375-R377 PolarHBondContact OD2-NH2 2.6Å; R377-N380 PolarHBondContact O-N 3.39Å; R377-V381 HydrophobicContact CB-CB 4.24Å; R377-V381 PolarHBondContact N-O 3.4Å; R377-V381 WeakPolarHBondContact O-CA 3.49Å; R377-V381 WeakPolarHBondContact O-CB 3.09Å; R377-V381 PolarHBondContact O-N 2.87Å; R377-R383 HydrophobicContact CG-CG 4.27Å
378E68.9Low91.6Very high77 Ų7731.1 Ų31.136%0.3616%0.163SC..THydrogen-bonded Turntrans-58.1152.7177.3-66.6-70.3175.400111.9R184 F376R184-E378 PolarHBondContact NE-O 2.8Å; R184-E378 VanDerWaalsContact NE-O 3.14Å; F376-E378 HydrophobicContact CE1-CG 4.07Å; F376-E378 WeakPolarHBondContact CE1-OE1 3.18Å
379P72.4Confident91.9Very high80 Ų8026.4 Ų26.452%0.51915%0.145SC..THydrogen-bonded Turncis-77.9-22.2-8.329.8-32.9000113.7
380N87.8Confident92.3Very high44 Ų4420.8 Ų20.824%0.23512%0.115CC..THydrogen-bonded Turntrans-152.424.4-158.469-20.1000114.6Q356 H357 A360 R377Q356-N380 VanDerWaalsContact CA-O 3.24Å; Q356-N380 WeakPolarHBondContact CA-O 3.48Å; H357-N380 PolarHBondContact N-O 3.39Å; H357-N380 WeakPolarHBondContact O-CB 3.28Å; A360-N380 WeakPolarHBondContact CB-O 3.42Å; R377-N380 PolarHBondContact O-N 3.39Å
381V92.6Very high92.5Very high1 Ų117.8 Ų17.81%0.00610%0.099CC..EExtended strand (participates in β ladder)trans-112128.5-173.5-173.90000111.9C354 Q356 F376 R377 R383C354-V381 HydrophobicContact CB-CG1 3.71Å; Q356-V381 HydrophobicContact CG-CG2 3.95Å; F376-V381 CarbonylContact C-O 3.57Å; F376-V381 WeakPolarHBondContact CA-O 3.47Å; F376-V381 VanDerWaalsContact CD2-O 3.28Å; F376-V381 WeakPolarHBondContact CD2-O 3.17Å; R377-V381 HydrophobicContact CB-CB 4.24Å; R377-V381 PolarHBondContact N-O 3.4Å; R377-V381 WeakPolarHBondContact O-CA 3.49Å; R377-V381 WeakPolarHBondContact O-CB 3.09Å; R377-V381 PolarHBondContact O-N 2.87Å; V381-R383 HydrophobicContact CG1-CG 4.11Å
382I96.4Very high92.7Very high0 Ų017 Ų170%09%0.09CC..EExtended strand (participates in β ladder)trans-101.5114166-49.2176.8000107.6L355 A360 I363 A364 L367 P374 D375 L384 L403L355-I382 PolarHBondContact N-O 2.94Å; L355-I382 PolarHBondContact O-N 3.39Å; A360-I382 HydrophobicContact CB-CD1 4.24Å; A360-I382 HydrophobicContact CB-CG1 3.75Å; I363-I382 HydrophobicContact CB-CD1 3.85Å; I363-I382 HydrophobicContact CG2-CD1 3.47Å; I363-I382 VanDerWaalsContact CG2-CD1 3.47Å; A364-I382 HydrophobicContact CB-CG1 4.41Å; L367-I382 HydrophobicContact CD1-CG2 4.21Å; P374-I382 HydrophobicContact CB-CG2 3.73Å; P374-I382 HydrophobicContact CG-CG2 4.43Å; D375-I382 CarbonylContact O-C 3.57Å; D375-I382 WeakPolarHBondContact O-CA 3.05Å; I382-L384 HydrophobicContact CG2-CD2 4.11Å; I382-L384 HydrophobicContact CG2-CG 4.24Å; I382-L403 HydrophobicContact CD1-CD2 4.48Å
383R97.7Very high92.7Very high0 Ų017.4 Ų17.40%09%0.091CC..EExtended strand (participates in β ladder)trans-88.5123174.4-59.5-166.6-57.5150.48.5109.3N40 Y183 H211 V353 D375 R377 V381N40-R383 VanDerWaalsContact ND2-CZ 3.29Å; N40-R383 PolarHBondContact ND2-NH1 3.45Å; Y183-R383 WeakPolarHBondContact O-CD 3.28Å; Y183-R383 PolarHBondContact O-NH1 3.08Å; H211-R383 PolarHBondContact CE1-NH1 3.48Å; V353-R383 WeakPolarHBondContact O-CA 3.49Å; D375-R383 HydrophobicContact CB-CB 4.28Å; D375-R383 PolarHBondContact N-O 2.84Å; D375-R383 VanDerWaalsContact N-O 3.14Å; D375-R383 PolarHBondContact O-N 2.87Å; D375-R383 IonicContact OD1-NH2 3.2Å; D375-R383 IonicContact OD2-CZ 2.73Å; D375-R383 IonicContact OD2-NE 3.59Å; D375-R383 PolarHBondContact OD2-NE 2.96Å; D375-R383 IonicContact OD2-NH2 2.85Å; D375-R383 PolarHBondContact OD2-NH2 3.18Å; R377-R383 HydrophobicContact CG-CG 4.27Å; V381-R383 HydrophobicContact CG1-CG 4.11Å
384L98.1Very high92.8Very high0 Ų018.9 Ų18.90%010%0.096CC..EExtended strand (participates in β ladder)trans-118.5116.7177.3-61.6171.2000108.1M37 L325 H352 V353 P374 I382 P386 V399 L403M37-L384 HydrophobicContact CB-CD2 4.12Å; M37-L384 HydrophobicContact CE-CB 4.05Å; M37-L384 HydrophobicContact CG-CD2 4.5Å; L325-L384 HydrophobicContact CD2-CB 4.03Å; H352-L384 WeakPolarHBondContact CA-O 3.4Å; H352-L384 WeakPolarHBondContact CB-O 3.39Å; V353-L384 PolarHBondContact N-O 3.43Å; V353-L384 PolarHBondContact O-N 3.03Å; P374-L384 HydrophobicContact CB-CD2 3.87Å; I382-L384 HydrophobicContact CG2-CD2 4.11Å; I382-L384 HydrophobicContact CG2-CG 4.24Å; L384-P386 VanDerWaalsContact O-CD 3.25Å; L384-P386 WeakPolarHBondContact O-CD 3.4Å; L384-V399 HydrophobicContact CD1-CG1 4.22Å; L384-V399 HydrophobicContact CD2-CG1 4.29Å; L384-L403 HydrophobicContact CD1-CD1 3.94Å
385A97.6Very high92.9Very high0 Ų019.3 Ų19.30%010%0.098CC..BIsolated β-bridgetrans-113.790.6-177.300000111.2M37 N40 H352 I387M37-A385 WeakPolarHBondContact O-CB 3.34Å; M37-A385 PolarHBondContact O-N 3.33Å; N40-A385 HydrophobicContact CB-CB 3.78Å; N40-A385 VanDerWaalsContact OD1-CB 3.31Å; N40-A385 WeakPolarHBondContact OD1-CB 3.3Å; H352-A385 HydrophobicContact CB-CB 3.67Å; A385-I387 HydrophobicContact CB-CD1 3.96Å; A385-I387 WeakPolarHBondContact O-CG1 3.39Å; A385-I387 PolarHBondContact O-N 2.9Å
386P97.5Very high93.2Very high0 Ų018.6 Ų18.60%09%0.094CC..  trans-63.6103.8166.8-14.125.4000110.2M37 K321 T322 L325 L384 T391 I396M37-P386 HydrophobicContact CE-CB 4.4Å; M37-P386 HydrophobicContact CE-CG 3.82Å; K321-P386 HydrophobicContact CB-CB 3.98Å; T322-P386 HydrophobicContact CG2-CB 4.39Å; T322-P386 HydrophobicContact CG2-CG 3.86Å; L325-P386 HydrophobicContact CB-CG 4.37Å; L325-P386 HydrophobicContact CD2-CG 3.63Å; L384-P386 VanDerWaalsContact O-CD 3.25Å; L384-P386 WeakPolarHBondContact O-CD 3.4Å; P386-T391 HydrophobicContact CB-CG2 4.16Å; P386-I396 HydrophobicContact CB-CD1 3.9Å; P386-I396 HydrophobicContact CB-CG1 4.22Å; P386-I396 HydrophobicContact CG-CD1 4.36Å; P386-I396 HydrophobicContact CG-CG1 4.43Å
387I97.5Very high93.7Very high10 Ų1017.4 Ų17.45%0.0519%0.089CC..  trans-83.4129.8-179.2-54.6-55.7000109.4Y235 A385 L389 Y390 T391Y235-I387 HydrophobicContact CD1-CD1 3.69Å; Y235-I387 HydrophobicContact CE1-CD1 3.57Å; A385-I387 HydrophobicContact CB-CD1 3.96Å; A385-I387 WeakPolarHBondContact O-CG1 3.39Å; A385-I387 PolarHBondContact O-N 2.9Å; I387-L389 PolarHBondContact O-N 3.35Å; I387-L389 VanDerWaalsContact O-N 3.14Å; I387-Y390 HydrophobicContact CB-CD1 4.41Å; I387-Y390 HydrophobicContact CB-CD2 4.05Å; I387-Y390 HydrophobicContact CB-CE1 4.03Å; I387-Y390 HydrophobicContact CB-CE2 3.62Å; I387-Y390 HydrophobicContact CB-CG 4.44Å; I387-Y390 HydrophobicContact CG1-CE1 4.39Å; I387-Y390 HydrophobicContact CG1-CE2 3.68Å; I387-Y390 HydrophobicContact CG2-CD1 3.94Å; I387-Y390 HydrophobicContact CG2-CD2 4.47Å; I387-Y390 HydrophobicContact CG2-CE1 3.52Å; I387-Y390 HydrophobicContact CG2-CE2 4.09Å; I387-Y390 HydrophobicContact CG2-CG 4.41Å; I387-Y390 PolarHBondContact O-N 2.92Å; I387-T391 PolarHBondContact N-OG1 3.12Å; I387-T391 WeakPolarHBondContact O-CB 3.4Å; I387-T391 PolarHBondContact O-N 3.17Å
388A97Very high94.3Very high3 Ų318.1 Ų18.13%0.02510%0.096CC..THydrogen-bonded Turntrans-53.8-39.2-174.700000113.5L21 I314 N317 K321L21-A388 HydrophobicContact CD1-CB 4.3Å; I314-A388 HydrophobicContact CG2-CB 4.04Å; I314-A388 WeakPolarHBondContact O-CB 3.43Å; N317-A388 HydrophobicContact CB-CB 4.1Å; N317-A388 VanDerWaalsContact OD1-CA 3.23Å; N317-A388 WeakPolarHBondContact OD1-CA 3.43Å; N317-A388 WeakPolarHBondContact OD1-CB 3.12Å; N317-A388 PolarHBondContact OD1-O 2.94Å; K321-A388 PolarHBondContact NZ-O 2.89Å
389L96.9Very high95.7Very high3 Ų314.4 Ų14.42%0.0168%0.079CC..THydrogen-bonded Turntrans-79.7-25-171.5-59.4179.3000114.4Y24 R25 F28 I305 F306 L309 I314 I387Y24-L389 CarbonylContact C-O 3.55Å; Y24-L389 VanDerWaalsContact C-O 3.26Å; R25-L389 WeakPolarHBondContact CA-O 3.07Å; R25-L389 PolarHBondContact N-O 3.07Å; F28-L389 HydrophobicContact CE2-CB 3.71Å; F28-L389 HydrophobicContact CE2-CD1 4.25Å; F28-L389 HydrophobicContact CZ-CB 3.96Å; F28-L389 HydrophobicContact CZ-CD1 3.75Å; I305-L389 HydrophobicContact CG2-CD1 4.16Å; I305-L389 HydrophobicContact CG2-CD2 4.3Å; F306-L389 HydrophobicContact CE2-CD1 4.17Å; F306-L389 HydrophobicContact CZ-CD1 4.05Å; L309-L389 HydrophobicContact CD1-CD2 3.32Å; I314-L389 HydrophobicContact CG1-CD2 4.47Å; I387-L389 PolarHBondContact O-N 3.35Å; I387-L389 VanDerWaalsContact O-N 3.14Å
390Y96.7Very high97Very high2 Ų210.6 Ų10.61%0.0085%0.054CC..THydrogen-bonded Turntrans-146.8-2.4-168.759.4-111.3000116.1R25 F28 I30 Y36 G39 M44 I387R25-Y390 PolarHBondContact NH1-O 3.05Å; F28-Y390 HydrophobicContact CB-CD1 4.43Å; F28-Y390 AromaticContact CD1-CD1 3.69Å; F28-Y390 HydrophobicContact CD1-CD1 3.69Å; F28-Y390 HydrophobicContact CD1-CE1 4.09Å; F28-Y390 AromaticContact CD2-CD1 3.89Å; F28-Y390 HydrophobicContact CD2-CD1 3.89Å; F28-Y390 HydrophobicContact CD2-CG 4.35Å; F28-Y390 AromaticContact CE1-CD1 3.84Å; F28-Y390 HydrophobicContact CE1-CD1 3.84Å; F28-Y390 HydrophobicContact CE1-CE1 4.1Å; F28-Y390 HydrophobicContact CE2-CD1 4.06Å; F28-Y390 AromaticContact CG-CD1 3.72Å; F28-Y390 HydrophobicContact CG-CD1 3.72Å; F28-Y390 HydrophobicContact CG-CG 4.23Å; F28-Y390 HydrophobicContact CZ-CD1 4.03Å; I30-Y390 HydrophobicContact CD1-CD2 4.12Å; I30-Y390 HydrophobicContact CD1-CG 4.27Å; Y36-Y390 HydrophobicContact CD1-CE2 4.2Å; G39-Y390 VanDerWaalsContact CA-OH 3.3Å; G39-Y390 WeakPolarHBondContact CA-OH 3.44Å; M44-Y390 HydrophobicContact CB-CD1 4.42Å; M44-Y390 HydrophobicContact CB-CE1 4.01Å; M44-Y390 HydrophobicContact CB-CE2 4.39Å; M44-Y390 HydrophobicContact CG-CD2 4.23Å; M44-Y390 HydrophobicContact CG-CE1 4.22Å; M44-Y390 HydrophobicContact CG-CE2 3.71Å; M44-Y390 PolarHBondContact N-OH 2.9Å; I387-Y390 HydrophobicContact CB-CD1 4.41Å; I387-Y390 HydrophobicContact CB-CD2 4.05Å; I387-Y390 HydrophobicContact CB-CE1 4.03Å; I387-Y390 HydrophobicContact CB-CE2 3.62Å; I387-Y390 HydrophobicContact CB-CG 4.44Å; I387-Y390 HydrophobicContact CG1-CE1 4.39Å; I387-Y390 HydrophobicContact CG1-CE2 3.68Å; I387-Y390 HydrophobicContact CG2-CD1 3.94Å; I387-Y390 HydrophobicContact CG2-CD2 4.47Å; I387-Y390 HydrophobicContact CG2-CE1 3.52Å; I387-Y390 HydrophobicContact CG2-CE2 4.09Å; I387-Y390 HydrophobicContact CG2-CG 4.41Å; I387-Y390 PolarHBondContact O-N 2.92Å
391T97.6Very high97.5Very high1 Ų111.8 Ų11.81%0.0066%0.058CC..  trans-92.8128.6168.5-53.40000109.7M37 K321 P386 I387 E395 I396M37-T391 HydrophobicContact SD-CG2 3.73Å; K321-T391 VanDerWaalsContact CE-O 3.22Å; K321-T391 WeakPolarHBondContact CE-O 3.49Å; K321-T391 PolarHBondContact NZ-O 3.14Å; P386-T391 HydrophobicContact CB-CG2 4.16Å; I387-T391 PolarHBondContact N-OG1 3.12Å; I387-T391 WeakPolarHBondContact O-CB 3.4Å; I387-T391 PolarHBondContact O-N 3.17Å; T391-E395 WeakPolarHBondContact CA-OE2 3.49Å; T391-E395 HydrophobicContact CG2-CB 4.36Å; T391-I396 HydrophobicContact CG2-CD1 4.39Å; T391-I396 HydrophobicContact CG2-CG1 3.93Å
392S97.5Very high97.7Very high7 Ų713 Ų135%0.0497%0.066CC..  trans-90.1161.8177.182.10000112.8D16 E394 E395 I396D16-S392 WeakPolarHBondContact OD1-CA 3.44Å; D16-S392 VanDerWaalsContact OD1-CB 3.27Å; D16-S392 WeakPolarHBondContact OD1-CB 3.22Å; S392-E394 VanDerWaalsContact C-N 3.34Å; S392-E394 PolarHBondContact OG-N 2.8Å; S392-E395 PolarHBondContact N-OE2 3.25Å; S392-E395 PolarHBondContact O-N 3.42Å; S392-E395 WeakPolarHBondContact OG-CB 3.12Å; S392-E395 VanDerWaalsContact OG-CG 3.31Å; S392-E395 WeakPolarHBondContact OG-CG 3.37Å; S392-E395 PolarHBondContact OG-N 3.14Å; S392-I396 WeakPolarHBondContact O-CG1 3.3Å; S392-I396 PolarHBondContact O-N 2.95Å; S392-I396 VanDerWaalsContact O-N 3.09Å
393Y98.3Very high97.8Very high10 Ų1013 Ų134%0.0397%0.066CC..Hα-helixtrans-67.8-35.9172.7-71.6-92.7000111.4A12 L15 D16 D19 N320 K321 Y324 E395 I396 N397A12-Y393 WeakPolarHBondContact O-CB 3.28Å; L15-Y393 HydrophobicContact CB-CD1 3.83Å; L15-Y393 HydrophobicContact CB-CD2 3.89Å; L15-Y393 HydrophobicContact CB-CE1 4.31Å; L15-Y393 HydrophobicContact CB-CE2 4.38Å; L15-Y393 HydrophobicContact CB-CG 3.59Å; L15-Y393 HydrophobicContact CD1-CD1 3.54Å; L15-Y393 HydrophobicContact CD1-CE1 3.94Å; L15-Y393 HydrophobicContact CD1-CG 4.14Å; L15-Y393 HydrophobicContact CG-CD1 4.32Å; D16-Y393 WeakPolarHBondContact OD1-CD2 3.37Å; D16-Y393 PolarHBondContact OD1-N 2.93Å; D16-Y393 PolarHBondContact OD2-N 3.35Å; D19-Y393 HydrophobicContact CB-CD2 4.37Å; D19-Y393 HydrophobicContact CB-CE2 3.88Å; N320-Y393 VanDerWaalsContact CG-OH 3.31Å; N320-Y393 WeakPolarHBondContact OD1-CE1 3.36Å; N320-Y393 PolarHBondContact OD1-OH 2.96Å; K321-Y393 HydrophobicContact CD-CE2 4.48Å; K321-Y393 HydrophobicContact CG-CE1 3.97Å; K321-Y393 HydrophobicContact CG-CE2 3.9Å; Y324-Y393 AromaticContact CD1-CD1 3.54Å; Y324-Y393 HydrophobicContact CD1-CD1 3.54Å; Y324-Y393 HydrophobicContact CD1-CE1 4.32Å; Y324-Y393 HydrophobicContact CD1-CG 4.47Å; Y324-Y393 HydrophobicContact CE1-CD1 4.14Å; Y324-Y393 AromaticContact CG-CD1 3.94Å; Y324-Y393 HydrophobicContact CG-CD1 3.94Å; Y324-Y393 HydrophobicContact CG-CE1 4.33Å; Y393-E395 VanDerWaalsContact C-N 3.34Å; Y393-I396 PolarHBondContact O-N 3.19Å; Y393-N397 PolarHBondContact O-N 3.29Å
394E98Very high97.8Very high61 Ų6115.7 Ų15.729%0.2858%0.077SC..Hα-helixtrans-54.8-48.6169.2165.8163.3-148.100111.5L9 K13 D16 S392 I396 N397 L398L9-E394 HydrophobicContact CD1-CB 4.45Å; L9-E394 HydrophobicContact CD1-CG 3.86Å; K13-E394 WeakPolarHBondContact CE-OE1 3.37Å; K13-E394 VanDerWaalsContact CE-OE2 3.24Å; K13-E394 WeakPolarHBondContact CE-OE2 3.18Å; K13-E394 HydrophobicContact CG-CB 4.4Å; K13-E394 IonicContact NZ-OE1 2.88Å; K13-E394 PolarHBondContact NZ-OE1 2.86Å; K13-E394 IonicContact NZ-OE2 2.99Å; D16-E394 WeakPolarHBondContact OD2-CB 2.99Å; D16-E394 PolarHBondContact OD2-N 3.28Å; S392-E394 VanDerWaalsContact C-N 3.34Å; S392-E394 PolarHBondContact OG-N 2.8Å; E394-I396 PolarHBondContact O-N 3.17Å; E394-N397 WeakPolarHBondContact O-CB 3.42Å; E394-N397 PolarHBondContact O-N 3.48Å; E394-N397 VanDerWaalsContact O-N 3.17Å; E394-L398 HydrophobicContact CG-CD1 4.04Å; E394-L398 WeakPolarHBondContact O-CG 3.42Å; E394-L398 PolarHBondContact O-N 3.49Å
395E97.8Very high97.8Very high13 Ų1320 Ų206%0.06110%0.096CC..Hα-helixtrans-61.5-43.3177.7-77.9175.5145.900111.8R25 I35 T391 S392 Y393 N397 L398 V399R25-E395 IonicContact CZ-OE1 3.9Å; R25-E395 IonicContact CZ-OE2 3.53Å; R25-E395 VanDerWaalsContact NH1-CD 3.32Å; R25-E395 IonicContact NH1-OE1 2.74Å; R25-E395 PolarHBondContact NH1-OE1 3.43Å; R25-E395 IonicContact NH1-OE2 2.98Å; R25-E395 PolarHBondContact NH1-OE2 3.29Å; R25-E395 VanDerWaalsContact NH1-OE2 3.09Å; R25-E395 IonicContact NH2-OE1 3.14Å; R25-E395 PolarHBondContact NH2-OE1 3.18Å; I35-E395 HydrophobicContact CD1-CG 4.48Å; I35-E395 HydrophobicContact CG1-CG 4.18Å; I35-E395 HydrophobicContact CG2-CB 3.7Å; I35-E395 HydrophobicContact CG2-CG 3.94Å; T391-E395 WeakPolarHBondContact CA-OE2 3.49Å; T391-E395 HydrophobicContact CG2-CB 4.36Å; S392-E395 PolarHBondContact N-OE2 3.25Å; S392-E395 PolarHBondContact O-N 3.42Å; S392-E395 WeakPolarHBondContact OG-CB 3.12Å; S392-E395 VanDerWaalsContact OG-CG 3.31Å; S392-E395 WeakPolarHBondContact OG-CG 3.37Å; S392-E395 PolarHBondContact OG-N 3.14Å; Y393-E395 VanDerWaalsContact C-N 3.34Å; E395-N397 VanDerWaalsContact C-N 3.29Å; E395-N397 PolarHBondContact O-N 2.71Å; E395-L398 PolarHBondContact O-N 3.38Å; E395-V399 VanDerWaalsContact O-CG2 3.3Å; E395-V399 WeakPolarHBondContact O-CG2 3.41Å; E395-V399 PolarHBondContact O-N 2.89Å
396I98.4Very high97.8Very high0 Ų020 Ų200%010%0.096CC..Hα-helixtrans-57.9-43.1174.8-68.4165.5000111K321 Y324 L325 L328 P386 T391 S392 Y393 E394 V399 V400K321-I396 HydrophobicContact CB-CD1 3.72Å; K321-I396 HydrophobicContact CD-CD1 4.43Å; K321-I396 HydrophobicContact CG-CD1 4Å; Y324-I396 HydrophobicContact CD1-CB 4.2Å; Y324-I396 HydrophobicContact CD1-CG2 3.66Å; Y324-I396 HydrophobicContact CE1-CB 4.45Å; Y324-I396 HydrophobicContact CE1-CG2 4.1Å; L325-I396 HydrophobicContact CB-CG2 3.69Å; L325-I396 HydrophobicContact CD1-CG2 4.02Å; L325-I396 HydrophobicContact CG-CG2 4.43Å; L328-I396 HydrophobicContact CD1-CG2 4.23Å; P386-I396 HydrophobicContact CB-CD1 3.9Å; P386-I396 HydrophobicContact CB-CG1 4.22Å; P386-I396 HydrophobicContact CG-CD1 4.36Å; P386-I396 HydrophobicContact CG-CG1 4.43Å; T391-I396 HydrophobicContact CG2-CD1 4.39Å; T391-I396 HydrophobicContact CG2-CG1 3.93Å; S392-I396 WeakPolarHBondContact O-CG1 3.3Å; S392-I396 PolarHBondContact O-N 2.95Å; S392-I396 VanDerWaalsContact O-N 3.09Å; Y393-I396 PolarHBondContact O-N 3.19Å; E394-I396 PolarHBondContact O-N 3.17Å; I396-V399 PolarHBondContact O-N 3.04Å; I396-V400 PolarHBondContact O-N 2.97Å
397N98.4Very high97.7Very high4 Ų420.7 Ų20.72%0.02110%0.1CC..Hα-helixtrans-62.4-47.8176.5-172.8-94.4000111.7A12 L328 Y393 E394 E395 V399 V400 Q401A12-N397 HydrophobicContact CB-CB 3.75Å; L328-N397 HydrophobicContact CD1-CB 4.13Å; Y393-N397 PolarHBondContact O-N 3.29Å; E394-N397 WeakPolarHBondContact O-CB 3.42Å; E394-N397 PolarHBondContact O-N 3.48Å; E394-N397 VanDerWaalsContact O-N 3.17Å; E395-N397 VanDerWaalsContact C-N 3.29Å; E395-N397 PolarHBondContact O-N 2.71Å; N397-V399 PolarHBondContact O-N 3.14Å; N397-V400 PolarHBondContact O-N 3.07Å; N397-Q401 WeakPolarHBondContact O-CG 3.4Å; N397-Q401 PolarHBondContact O-N 3.36Å
398L98.1Very high97.6Very high64 Ų6422.7 Ų22.734%0.33512%0.118SC..Hα-helixtrans-61.7-40.5179-68.5173.2000112.2L9 I35 E394 E395 V400 Q401 T402L9-L398 HydrophobicContact CD1-CD2 4.41Å; L9-L398 HydrophobicContact CD1-CG 4.49Å; I35-L398 HydrophobicContact CD1-CB 3.73Å; I35-L398 HydrophobicContact CD1-CD1 4.11Å; E394-L398 HydrophobicContact CG-CD1 4.04Å; E394-L398 WeakPolarHBondContact O-CG 3.42Å; E394-L398 PolarHBondContact O-N 3.49Å; E395-L398 PolarHBondContact O-N 3.38Å; L398-V400 VanDerWaalsContact C-N 3.33Å; L398-V400 PolarHBondContact O-N 2.94Å; L398-Q401 PolarHBondContact O-N 3.29Å; L398-T402 WeakPolarHBondContact O-CB 3.24Å; L398-T402 PolarHBondContact O-N 2.95Å; L398-T402 PolarHBondContact O-OG1 3.34Å
399V98.3Very high97.6Very high0 Ų028.4 Ų28.40%015%0.145CC..Hα-helixtrans-57.6-46.3175.51690000111.1I35 M37 V372 L384 E395 I396 N397 T402 L403I35-V399 HydrophobicContact CB-CG2 4.43Å; I35-V399 HydrophobicContact CD1-CG2 4.45Å; I35-V399 HydrophobicContact CG2-CG2 3.63Å; M37-V399 HydrophobicContact CE-CG2 4.48Å; M37-V399 HydrophobicContact CG-CG2 3.95Å; M37-V399 HydrophobicContact SD-CG2 4.24Å; V372-V399 HydrophobicContact CG1-CG1 4.4Å; V372-V399 HydrophobicContact CG1-CG2 3.87Å; V372-V399 HydrophobicContact CG2-CG2 4.16Å; L384-V399 HydrophobicContact CD1-CG1 4.22Å; L384-V399 HydrophobicContact CD2-CG1 4.29Å; E395-V399 VanDerWaalsContact O-CG2 3.3Å; E395-V399 WeakPolarHBondContact O-CG2 3.41Å; E395-V399 PolarHBondContact O-N 2.89Å; I396-V399 PolarHBondContact O-N 3.04Å; N397-V399 PolarHBondContact O-N 3.14Å; V399-T402 PolarHBondContact O-N 3.26Å; V399-L403 HydrophobicContact CG1-CD1 4.11Å; V399-L403 WeakPolarHBondContact O-CG 3.35Å; V399-L403 PolarHBondContact O-N 2.9Å
400V98.4Very high97.4Very high0 Ų033.1 Ų33.10%017%0.165CC..Hα-helixtrans-66.4-39.8178.8175.10000111.8L325 L328 I329 E332 L333 I396 N397 L398 T402 L403 K404L325-V400 HydrophobicContact CD1-CG2 3.6Å; L328-V400 HydrophobicContact CB-CB 4.16Å; L328-V400 HydrophobicContact CB-CG1 4.01Å; L328-V400 HydrophobicContact CB-CG2 3.79Å; L328-V400 HydrophobicContact CD1-CB 4.4Å; L328-V400 HydrophobicContact CD1-CG2 4.23Å; I329-V400 HydrophobicContact CG1-CG2 4.21Å; E332-V400 HydrophobicContact CB-CG1 3.82Å; E332-V400 HydrophobicContact CG-CG1 4.29Å; L333-V400 HydrophobicContact CD1-CG1 4.14Å; L333-V400 HydrophobicContact CD2-CG1 4.28Å; L333-V400 HydrophobicContact CG-CG1 3.96Å; I396-V400 PolarHBondContact O-N 2.97Å; N397-V400 PolarHBondContact O-N 3.07Å; L398-V400 VanDerWaalsContact C-N 3.33Å; L398-V400 PolarHBondContact O-N 2.94Å; V400-T402 VanDerWaalsContact C-N 3.33Å; V400-T402 PolarHBondContact O-N 3.31Å; V400-L403 PolarHBondContact O-N 3.25Å; V400-K404 WeakPolarHBondContact O-CB 3.47Å; V400-K404 PolarHBondContact O-N 3.1Å
401Q98Very high97.1Very high69 Ų6934 Ų3432%0.32217%0.169SC..Hα-helixtrans-65-37.6175-63.2-53.6-52.100112.1N397 L398 K404 K405N397-Q401 WeakPolarHBondContact O-CG 3.4Å; N397-Q401 PolarHBondContact O-N 3.36Å; L398-Q401 PolarHBondContact O-N 3.29Å; Q401-K404 WeakPolarHBondContact O-CB 3.47Å; Q401-K404 PolarHBondContact O-N 2.99Å; Q401-K405 WeakPolarHBondContact O-CB 3.48Å; Q401-K405 PolarHBondContact O-N 2.88Å
402T97.9Very high96.3Very high26 Ų2634.9 Ų34.916%0.1617%0.173CC..Hα-helixtrans-67.6-43.6175.6-58.40000111.5L367 N370 V372 L398 V399 V400 K404 K405 I406L367-T402 HydrophobicContact CD2-CG2 3.85Å; N370-T402 HydrophobicContact CB-CG2 3.69Å; V372-T402 HydrophobicContact CG2-CG2 4.41Å; L398-T402 WeakPolarHBondContact O-CB 3.24Å; L398-T402 PolarHBondContact O-N 2.95Å; L398-T402 PolarHBondContact O-OG1 3.34Å; V399-T402 PolarHBondContact O-N 3.26Å; V400-T402 VanDerWaalsContact C-N 3.33Å; V400-T402 PolarHBondContact O-N 3.31Å; T402-K404 VanDerWaalsContact C-N 3.32Å; T402-K404 PolarHBondContact O-N 3.45Å; T402-K405 PolarHBondContact O-N 2.88Å; T402-I406 HydrophobicContact CG2-CD1 3.83Å; T402-I406 HydrophobicContact CG2-CG1 4.4Å; T402-I406 WeakPolarHBondContact O-CB 3.43Å; T402-I406 VanDerWaalsContact O-CG1 3.25Å; T402-I406 WeakPolarHBondContact O-CG1 3.49Å; T402-I406 PolarHBondContact O-N 3Å
403L98.3Very high95.6Very high0 Ų039.5 Ų39.50%019%0.194CC..Hα-helixtrans-55.9-46.9171.9-79166.5000111.6L333 Y338 L355 I363 L367 I382 L384 V399 V400 I406 V407L333-L403 HydrophobicContact CD1-CB 3.84Å; L333-L403 HydrophobicContact CD1-CD1 3.92Å; L333-L403 HydrophobicContact CD2-CB 4.3Å; Y338-L403 HydrophobicContact CE1-CD2 4.31Å; Y338-L403 WeakPolarHBondContact OH-CD2 3.49Å; Y338-L403 PolarHBondContact OH-O 2.93Å; L355-L403 HydrophobicContact CD2-CD1 3.93Å; L355-L403 HydrophobicContact CD2-CD2 4.41Å; I363-L403 HydrophobicContact CG2-CD2 3.82Å; L367-L403 HydrophobicContact CD1-CD2 3.74Å; L367-L403 HydrophobicContact CD1-CG 4.45Å; L367-L403 HydrophobicContact CD2-CD2 4.08Å; L367-L403 HydrophobicContact CD2-CG 4.1Å; L367-L403 HydrophobicContact CG-CD2 4.21Å; I382-L403 HydrophobicContact CD1-CD2 4.48Å; L384-L403 HydrophobicContact CD1-CD1 3.94Å; V399-L403 HydrophobicContact CG1-CD1 4.11Å; V399-L403 WeakPolarHBondContact O-CG 3.35Å; V399-L403 PolarHBondContact O-N 2.9Å; V400-L403 PolarHBondContact O-N 3.25Å; L403-I406 PolarHBondContact O-N 3.07Å; L403-V407 PolarHBondContact O-N 3.19Å
404K98Very high94.4Very high57 Ų5745.7 Ų45.725%0.24822%0.223CC..Hα-helixtrans-59-49.7177.1-169.4178.6-171.5173.60110.8E332 L333 Y336 V400 Q401 T402 V407 A408E332-K404 HydrophobicContact CB-CD 4.46Å; E332-K404 IonicContact OE2-NZ 2.98Å; E332-K404 PolarHBondContact OE2-NZ 2.93Å; L333-K404 HydrophobicContact CD2-CB 3.52Å; L333-K404 HydrophobicContact CD2-CG 4.09Å; Y336-K404 HydrophobicContact CE2-CG 3.88Å; V400-K404 WeakPolarHBondContact O-CB 3.47Å; V400-K404 PolarHBondContact O-N 3.1Å; Q401-K404 WeakPolarHBondContact O-CB 3.47Å; Q401-K404 PolarHBondContact O-N 2.99Å; T402-K404 VanDerWaalsContact C-N 3.32Å; T402-K404 PolarHBondContact O-N 3.45Å; K404-V407 PolarHBondContact O-N 2.71Å; K404-A408 WeakPolarHBondContact O-CB 3.4Å; K404-A408 PolarHBondContact O-N 2.87Å
405K97.5Very high92.6Very high91 Ų9143.6 Ų43.640%0.39621%0.212SC..Hα-helixtrans-58.4-49.2178.8-172.3-169.7176.1-169.70111.5Q401 T402 V407 A408 E409 I411Q401-K405 WeakPolarHBondContact O-CB 3.48Å; Q401-K405 PolarHBondContact O-N 2.88Å; T402-K405 PolarHBondContact O-N 2.88Å; K405-V407 VanDerWaalsContact C-N 3.3Å; K405-V407 PolarHBondContact O-N 2.84Å; K405-A408 PolarHBondContact O-N 3.13Å; K405-E409 WeakPolarHBondContact CE-OE2 3.45Å; K405-E409 HydrophobicContact CG-CG 4.28Å; K405-E409 WeakPolarHBondContact CG-OE1 3.46Å; K405-E409 VanDerWaalsContact O-CB 3.3Å; K405-E409 WeakPolarHBondContact O-CB 3.46Å; K405-E409 PolarHBondContact O-N 3.05Å; K405-I411 HydrophobicContact CD-CD1 4.18Å; K405-I411 HydrophobicContact CG-CD1 4.05Å
406I96.9Very high90.4Very high0 Ų044.3 Ų44.30%022%0.219CC..Hα-helixtrans-56.3-45.5-178.2-73.5164.3000111.1I363 A366 L367 T402 L403 K410 I411 Y412I363-I406 HydrophobicContact CB-CG2 4.37Å; I363-I406 HydrophobicContact CG1-CG2 4.12Å; I363-I406 HydrophobicContact CG2-CG2 4.17Å; A366-I406 HydrophobicContact CB-CB 4.47Å; A366-I406 HydrophobicContact CB-CD1 3.73Å; A366-I406 HydrophobicContact CB-CG1 3.9Å; A366-I406 HydrophobicContact CB-CG2 3.7Å; L367-I406 HydrophobicContact CB-CD1 4.36Å; L367-I406 HydrophobicContact CD2-CD1 3.71Å; L367-I406 HydrophobicContact CG-CD1 3.78Å; T402-I406 HydrophobicContact CG2-CD1 3.83Å; T402-I406 HydrophobicContact CG2-CG1 4.4Å; T402-I406 WeakPolarHBondContact O-CB 3.43Å; T402-I406 VanDerWaalsContact O-CG1 3.25Å; T402-I406 WeakPolarHBondContact O-CG1 3.49Å; T402-I406 PolarHBondContact O-N 3Å; L403-I406 PolarHBondContact O-N 3.07Å; I406-K410 CarbonylContact O-C 3.54Å; I406-K410 WeakPolarHBondContact O-CA 3.35Å; I406-K410 PolarHBondContact O-N 3.35Å; I406-K410 VanDerWaalsContact O-N 3.12Å; I406-I411 HydrophobicContact CG1-CB 4.48Å; I406-I411 HydrophobicContact CG1-CD1 4.43Å; I406-I411 HydrophobicContact CG2-CB 4.47Å; I406-I411 PolarHBondContact O-N 2.76Å; I406-Y412 HydrophobicContact CG2-CD1 4.21Å; I406-Y412 WeakPolarHBondContact O-CD1 3.22Å
407V95.9Very high88.2Confident14 Ų1445.2 Ų45.29%0.08522%0.224CC..Hα-helixtrans-80.3-42.3-178.1-177.60000112Y336 Y338 I363 L403 K404 K405 E409 K410 Y412Y336-V407 HydrophobicContact CD1-CB 4.26Å; Y336-V407 HydrophobicContact CD1-CG1 3.88Å; Y336-V407 HydrophobicContact CG-CG1 4.34Å; Y338-V407 HydrophobicContact CE2-CB 4.39Å; Y338-V407 HydrophobicContact CE2-CG2 3.79Å; Y338-V407 WeakPolarHBondContact OH-CG2 3.44Å; I363-V407 HydrophobicContact CD1-CG2 3.62Å; I363-V407 HydrophobicContact CG1-CG2 4.06Å; L403-V407 PolarHBondContact O-N 3.19Å; K404-V407 PolarHBondContact O-N 2.71Å; K405-V407 VanDerWaalsContact C-N 3.3Å; K405-V407 PolarHBondContact O-N 2.84Å; V407-E409 PolarHBondContact O-N 3.22Å; V407-K410 PolarHBondContact O-N 3.36Å; V407-Y412 HydrophobicContact CB-CE1 4.47Å; V407-Y412 HydrophobicContact CG1-CE1 4.28Å; V407-Y412 HydrophobicContact CG2-CD1 4.45Å
408A96.5Very high85.5Confident52 Ų5245.4 Ų45.443%0.4323%0.225SC..Hα-helixtrans-62.8-40.2179.500000113Y336 K404 K405Y336-A408 HydrophobicContact CD1-CB 4.46Å; Y336-A408 HydrophobicContact CE1-CB 3.55Å; K404-A408 WeakPolarHBondContact O-CB 3.4Å; K404-A408 PolarHBondContact O-N 2.87Å; K405-A408 PolarHBondContact O-N 3.13Å
409E96.6Very high83.9Confident123 Ų12342.3 Ų42.358%0.57521%0.209SC*.THydrogen-bonded Turntrans-92.71.8178.3-62.2177.1-167.100112.4K405 V407 I411K405-E409 WeakPolarHBondContact CE-OE2 3.45Å; K405-E409 HydrophobicContact CG-CG 4.28Å; K405-E409 WeakPolarHBondContact CG-OE1 3.46Å; K405-E409 VanDerWaalsContact O-CB 3.3Å; K405-E409 WeakPolarHBondContact O-CB 3.46Å; K405-E409 PolarHBondContact O-N 3.05Å; V407-E409 PolarHBondContact O-N 3.22Å; E409-I411 HydrophobicContact CB-CD1 4.31Å; E409-I411 HydrophobicContact CB-CG1 3.91Å; E409-I411 PolarHBondContact O-N 3.21Å
410K92.4Very high82.6Confident102 Ų10242.3 Ų42.344%0.44321%0.209SC..THydrogen-bonded Turntrans53.931.2-178.5-63.3169146.7-121.10114.2I406 V407 Y412 E413I406-K410 CarbonylContact O-C 3.54Å; I406-K410 WeakPolarHBondContact O-CA 3.35Å; I406-K410 PolarHBondContact O-N 3.35Å; I406-K410 VanDerWaalsContact O-N 3.12Å; V407-K410 PolarHBondContact O-N 3.36Å; K410-Y412 HydrophobicContact CB-CE1 4.15Å; K410-Y412 HydrophobicContact CG-CE1 4.16Å; K410-Y412 PolarHBondContact O-N 2.73Å; K410-E413 HydrophobicContact CB-CG 4.09Å; K410-E413 WeakPolarHBondContact CD-OE1 3.24Å; K410-E413 IonicContact NZ-OE1 3.65Å; K410-E413 PolarHBondContact NZ-OE1 3.38Å; K410-E413 VanDerWaalsContact O-CB 3.24Å; K410-E413 WeakPolarHBondContact O-CB 3.39Å; K410-E413 PolarHBondContact O-N 3.47Å
411I89.2Confident81.3Confident19 Ų1942.5 Ų42.510%0.09721%0.21CC..G310 helixtrans-55.9-29.9178.7-58.4176.5000111A366 K405 I406 E409 E413 E414 Y415A366-I411 HydrophobicContact CB-CG2 4.27Å; K405-I411 HydrophobicContact CD-CD1 4.18Å; K405-I411 HydrophobicContact CG-CD1 4.05Å; I406-I411 HydrophobicContact CG1-CB 4.48Å; I406-I411 HydrophobicContact CG1-CD1 4.43Å; I406-I411 HydrophobicContact CG2-CB 4.47Å; I406-I411 PolarHBondContact O-N 2.76Å; E409-I411 HydrophobicContact CB-CD1 4.31Å; E409-I411 HydrophobicContact CB-CG1 3.91Å; E409-I411 PolarHBondContact O-N 3.21Å; I411-E413 PolarHBondContact O-N 3.39Å; I411-E413 VanDerWaalsContact O-N 3.14Å; I411-E414 WeakPolarHBondContact O-CB 3.44Å; I411-E414 WeakPolarHBondContact O-CG 3.1Å; I411-E414 PolarHBondContact O-N 3.31Å; I411-Y415 HydrophobicContact CG2-CE2 4.43Å; I411-Y415 WeakPolarHBondContact O-CD2 3.48Å; I411-Y415 WeakPolarHBondContact O-CE2 3.22Å
412Y82.8Confident80.7Confident20 Ų2043.4 Ų43.48%0.07821%0.213CC..G310 helixtrans-60.2-20.7175.767.7-91.7000112.6E359 R362 I363 I406 V407 K410 E414 Y415E359-Y412 HydrophobicContact CB-CD2 3.72Å; E359-Y412 HydrophobicContact CB-CE2 3.96Å; E359-Y412 HydrophobicContact CB-CG 4.35Å; E359-Y412 HydrophobicContact CG-CD2 3.64Å; E359-Y412 HydrophobicContact CG-CE2 3.36Å; R362-Y412 HydrophobicContact CB-CD2 4.43Å; R362-Y412 VanDerWaalsContact CZ-CD2 3.5Å; R362-Y412 PolarHBondContact NE-O 3.06Å; R362-Y412 VanDerWaalsContact NH2-C 3.3Å; R362-Y412 VanDerWaalsContact NH2-CE2 3.29Å; R362-Y412 PolarHBondContact NH2-O 2.93Å; R362-Y412 VanDerWaalsContact NH2-O 3.13Å; I363-Y412 HydrophobicContact CG1-CD1 4.34Å; I363-Y412 HydrophobicContact CG1-CG 4.2Å; I406-Y412 HydrophobicContact CG2-CD1 4.21Å; I406-Y412 WeakPolarHBondContact O-CD1 3.22Å; V407-Y412 HydrophobicContact CB-CE1 4.47Å; V407-Y412 HydrophobicContact CG1-CE1 4.28Å; V407-Y412 HydrophobicContact CG2-CD1 4.45Å; K410-Y412 HydrophobicContact CB-CE1 4.15Å; K410-Y412 HydrophobicContact CG-CE1 4.16Å; K410-Y412 PolarHBondContact O-N 2.73Å; Y412-E414 VanDerWaalsContact C-N 3.25Å; Y412-E414 PolarHBondContact O-N 2.73Å; Y412-Y415 WeakPolarHBondContact O-CD2 3.28Å; Y412-Y415 PolarHBondContact O-N 3.49Å
413E82.4Confident80.4Confident105 Ų10542.9 Ų42.949%0.49121%0.209SC..G310 helixtrans-64.4-17.7170.7-64.8176.8178.600114.8R362 K410 I411 Y415R362-E413 VanDerWaalsContact NH2-N 3.15Å; K410-E413 HydrophobicContact CB-CG 4.09Å; K410-E413 WeakPolarHBondContact CD-OE1 3.24Å; K410-E413 IonicContact NZ-OE1 3.65Å; K410-E413 PolarHBondContact NZ-OE1 3.38Å; K410-E413 VanDerWaalsContact O-CB 3.24Å; K410-E413 WeakPolarHBondContact O-CB 3.39Å; K410-E413 PolarHBondContact O-N 3.47Å; I411-E413 PolarHBondContact O-N 3.39Å; I411-E413 VanDerWaalsContact O-N 3.14Å; E413-Y415 PolarHBondContact O-N 3.36Å
414E73.1Confident80Confident140 Ų14046.1 Ų46.165%0.65423%0.225SC*.G310 helixtrans-73-4.2172-59.3177.7176.600113.4I411 Y412I411-E414 WeakPolarHBondContact O-CB 3.44Å; I411-E414 WeakPolarHBondContact O-CG 3.1Å; I411-E414 PolarHBondContact O-N 3.31Å; Y412-E414 VanDerWaalsContact C-N 3.25Å; Y412-E414 PolarHBondContact O-N 2.73Å
415Y60Low79.5Confident16 Ų1645.5 Ų45.56%0.06322%0.223CC..SBendtrans-115.295.8-176.8-53.6-101.2000108.9R362 A365 A366 N369 I411 Y412 E413R362-Y415 WeakPolarHBondContact CD-O 3.43Å; R362-Y415 WeakPolarHBondContact CG-O 3.33Å; R362-Y415 PolarHBondContact NE-O 3.3Å; R362-Y415 VanDerWaalsContact NE-O 3.07Å; A365-Y415 HydrophobicContact CB-CD1 3.5Å; A365-Y415 VanDerWaalsContact CB-CD1 3.5Å; A365-Y415 HydrophobicContact CB-CE1 3.8Å; A365-Y415 HydrophobicContact CB-CG 4.14Å; A366-Y415 WeakPolarHBondContact CA-OH 3.45Å; A366-Y415 HydrophobicContact CB-CD2 4.3Å; A366-Y415 HydrophobicContact CB-CE2 3.61Å; N369-Y415 VanDerWaalsContact CB-OH 3.28Å; N369-Y415 WeakPolarHBondContact CB-OH 3.41Å; N369-Y415 WeakPolarHBondContact ND2-CE1 3.47Å; N369-Y415 PolarHBondContact ND2-OH 3.46Å; I411-Y415 HydrophobicContact CG2-CE2 4.43Å; I411-Y415 WeakPolarHBondContact O-CD2 3.48Å; I411-Y415 WeakPolarHBondContact O-CE2 3.22Å; Y412-Y415 WeakPolarHBondContact O-CD2 3.28Å; Y412-Y415 PolarHBondContact O-N 3.49Å; E413-Y415 PolarHBondContact O-N 3.36Å
416S51.5Low78.7Confident28 Ų2844.6 Ų44.620%0.19622%0.222CC..  trans-83.2-178.1-179.6-162.80000114K447S416-K447 VanDerWaalsContact CB-N 3.29Å
417N51.3Low78.1Confident20 Ų2047.4 Ų47.411%0.10724%0.237CC..  trans-130.215.7-148.2-65.7-38000113.4A482 E483 M484N417-A482 CarbonylContact O-C 3.15Å; N417-A482 VanDerWaalsContact O-C 3.23Å; N417-A482 VanDerWaalsContact O-CA 3.29Å; N417-A482 WeakPolarHBondContact O-CA 3.13Å; N417-A482 WeakPolarHBondContact O-CB 3.47Å; N417-E483 HydrophobicContact CB-CB 3.52Å; N417-E483 HydrophobicContact CB-CG 3.39Å; N417-E483 WeakPolarHBondContact CB-OE2 3.16Å; N417-E483 PolarHBondContact ND2-OE1 3.5Å; N417-E483 PolarHBondContact ND2-OE2 3.43Å; N417-E483 PolarHBondContact O-N 3.07Å; N417-M484 PolarHBondContact O-N 3.03Å
418T42.4Very low77.9Confident7 Ų747.2 Ų47.24%0.04324%0.235CC..EExtended strand (participates in β ladder)trans-104.7129172.9-60.80000110.9L441 V448 L449 M484 L486T418-L441 HydrophobicContact CG2-CD1 4.28Å; T418-V448 WeakPolarHBondContact O-CA 3.27Å; T418-L449 PolarHBondContact O-N 3.29Å; T418-M484 WeakPolarHBondContact CA-O 2.86Å; T418-M484 HydrophobicContact CG2-CE 3.62Å; T418-L486 HydrophobicContact CG2-CD1 4.35Å
419R64.4Low77.6Confident0 Ų047.7 Ų47.70%023%0.231CC..EExtended strand (participates in β ladder)trans-140.6154.2-178.1-56.1-172.5-150.9-1332.1115.4Y361 L449 S478 A479 A481 A482 M484 L486Y361-R419 PolarHBondContact OH-NH1 3.15Å; Y361-R419 PolarHBondContact OH-NH2 2.82Å; R419-L449 CarbonylContact C-O 3.45Å; R419-L449 WeakPolarHBondContact CA-O 3.41Å; R419-L449 HydrophobicContact CB-CB 4.33Å; R419-L449 HydrophobicContact CG-CB 3.62Å; R419-L449 HydrophobicContact CG-CD1 3.63Å; R419-L449 HydrophobicContact CG-CG 3.76Å; R419-L449 VanDerWaalsContact NE-CD1 3.34Å; R419-S478 WeakPolarHBondContact CD-O 3.42Å; R419-S478 PolarHBondContact NE-O 2.92Å; R419-S478 PolarHBondContact NH1-O 2.82Å; R419-A479 WeakPolarHBondContact CB-O 3.4Å; R419-A479 VanDerWaalsContact CD-C 3.44Å; R419-A479 VanDerWaalsContact CD-O 3.29Å; R419-A479 WeakPolarHBondContact CD-O 3.36Å; R419-A481 PolarHBondContact NE-O 3.04Å; R419-A481 PolarHBondContact NH2-O 3.02Å; R419-A482 HydrophobicContact CB-CB 3.42Å; R419-A482 VanDerWaalsContact CB-CB 3.42Å; R419-A482 HydrophobicContact CG-CB 3.18Å; R419-M484 PolarHBondContact N-O 2.69Å; R419-L486 PolarHBondContact O-N 2.75Å
420I72Confident77.7Confident0 Ų042.2 Ų42.20%021%0.205CC..EExtended strand (participates in β ladder)trans-123.893.9-176-59.6148.2000108.2V431 L433 V438 V448 L449 V450 E451I420-V431 HydrophobicContact CG2-CG2 3.55Å; I420-L433 HydrophobicContact CD1-CB 3.56Å; I420-L433 HydrophobicContact CD1-CD2 3.8Å; I420-L433 HydrophobicContact CD1-CG 4.29Å; I420-L433 HydrophobicContact CG1-CB 4.03Å; I420-V438 HydrophobicContact CD1-CG2 4.36Å; I420-V448 HydrophobicContact CD1-CG1 3.51Å; I420-L449 PolarHBondContact N-O 3.38Å; I420-V450 HydrophobicContact CB-CG2 4.33Å; I420-V450 HydrophobicContact CD1-CG2 3.69Å; I420-E451 PolarHBondContact O-N 2.84Å
421P70.3Confident77.9Confident3 Ų337.5 Ų37.52%0.01918%0.184CC..PPolyproline II helixtrans-70.6157172.230.7-35.7000111.1A479 V485 L486 K487P421-A479 HydrophobicContact CB-CB 3.94Å; P421-V485 HydrophobicContact CG-CG1 3.81Å; P421-L486 WeakPolarHBondContact CD-O 3.37Å; P421-K487 HydrophobicContact CG-CD 3.88Å; P421-K487 HydrophobicContact CG-CG 3.52Å
422K86.1Confident78.2Confident89 Ų8936.8 Ų36.839%0.38718%0.181SC..PPolyproline II helixtrans-70.6138.1172.4-178.4177.3176.4-172.10109.8E451 A454K422-E451 HydrophobicContact CB-CB 4.3Å; K422-E451 VanDerWaalsContact CB-CD 3.44Å; K422-E451 HydrophobicContact CB-CG 4.19Å; K422-E451 WeakPolarHBondContact CB-OE2 3.46Å; K422-E451 PolarHBondContact N-OE2 2.95Å; K422-A454 HydrophobicContact CB-CB 4.2Å
423E91.7Very high78.8Confident15 Ų1535.9 Ų35.97%0.0718%0.178CC..PPolyproline II helixtrans-69.8131.9172.6-72.8-60.9154.800111.2E428 K487 V488 K489E423-E428 HydrophobicContact CB-CB 4.03Å; E423-E428 HydrophobicContact CB-CG 3.61Å; E423-E428 HydrophobicContact CG-CG 3.78Å; E423-K487 WeakPolarHBondContact OE1-CB 3.43Å; E423-K487 IonicContact OE1-NZ 3.37Å; E423-K487 PolarHBondContact OE1-NZ 3.07Å; E423-K487 IonicContact OE2-NZ 2.62Å; E423-K487 PolarHBondContact OE2-NZ 3.19Å; E423-V488 HydrophobicContact CG-CB 4.05Å; E423-V488 HydrophobicContact CG-CG2 4.17Å; E423-V488 WeakPolarHBondContact OE1-CA 3.47Å; E423-V488 PolarHBondContact OE1-N 3.34Å; E423-K489 PolarHBondContact OE1-N 3.06Å
424I90.1Very high79.5Confident67 Ų6730.9 Ų30.934%0.34415%0.154SC..  trans-108.8-10.6-176.664.6162.4000113.3L492 E495I424-L492 HydrophobicContact CD1-CB 4.08Å; I424-L492 HydrophobicContact CD1-CD1 3.83Å; I424-L492 HydrophobicContact CD1-CG 4.15Å; I424-L492 HydrophobicContact CG1-CD1 3.8Å; I424-L492 HydrophobicContact CG1-CG 4.22Å; I424-E495 VanDerWaalsContact CD1-CD 3.48Å; I424-E495 HydrophobicContact CD1-CG 3.56Å; I424-E495 HydrophobicContact CG1-CG 4.33Å
425K85.6Confident80.6Confident45 Ų4525.2 Ų25.220%0.19613%0.13CC..SBendtrans-64.9142.6178.2-167.9170.5-172.5171.60109.7N427 E428 K489 E490 L492K425-N427 PolarHBondContact O-N 2.58Å; K425-N427 VanDerWaalsContact O-N 3.15Å; K425-E428 HydrophobicContact CB-CB 3.96Å; K425-E428 WeakPolarHBondContact O-CB 3.46Å; K425-E428 PolarHBondContact O-N 3.27Å; K425-K489 HydrophobicContact CD-CB 4.31Å; K425-K489 HydrophobicContact CD-CG 4.25Å; K425-E490 IonicContact NZ-OE1 3.99Å; K425-E490 PolarHBondContact NZ-OE1 2.81Å; K425-E490 IonicContact NZ-OE2 3.66Å; K425-L492 HydrophobicContact CB-CD1 4.46Å
426N80.8Confident82.1Confident72 Ų7227.6 Ų27.639%0.38515%0.149SC..THydrogen-bonded Turntrans-50.3120.5-174.4-170.190.1000112.8E428 D699 N715N426-E428 PolarHBondContact O-N 3.39Å; N426-E428 VanDerWaalsContact O-N 3.15Å; N426-D699 PolarHBondContact ND2-OD2 2.95Å; N426-D699 PolarHBondContact OD1-OD2 3.21Å; N426-N715 PolarHBondContact O-ND2 2.84Å
427N84.2Confident84.1Confident58 Ų5826.4 Ų26.431%0.3114%0.141SC..THydrogen-bonded Turntrans5131.5-177.4-70.4-39.2000113.8K425 N429 H698 D699K425-N427 PolarHBondContact O-N 2.58Å; K425-N427 VanDerWaalsContact O-N 3.15Å; N427-N429 PolarHBondContact O-N 2.85Å; N427-N429 PolarHBondContact O-ND2 3.3Å; N427-H698 HydrophobicContact CB-CB 3.85Å; N427-D699 VanDerWaalsContact ND2-CG 3.29Å; N427-D699 PolarHBondContact ND2-OD1 3.44Å; N427-D699 PolarHBondContact ND2-OD2 3.49Å
428E91.6Very high86.2Confident10 Ų1025.4 Ų25.45%0.04714%0.135CC..  trans-8393.1166.1-174.455-100.900109.4E423 K425 N426 R430 K489 N715E423-E428 HydrophobicContact CB-CB 4.03Å; E423-E428 HydrophobicContact CB-CG 3.61Å; E423-E428 HydrophobicContact CG-CG 3.78Å; K425-E428 HydrophobicContact CB-CB 3.96Å; K425-E428 WeakPolarHBondContact O-CB 3.46Å; K425-E428 PolarHBondContact O-N 3.27Å; N426-E428 PolarHBondContact O-N 3.39Å; N426-E428 VanDerWaalsContact O-N 3.15Å; E428-R430 VanDerWaalsContact CD-NH2 3.31Å; E428-R430 WeakPolarHBondContact OE1-CB 3.39Å; E428-R430 WeakPolarHBondContact OE1-CG 3.48Å; E428-R430 IonicContact OE1-CZ 3.54Å; E428-R430 PolarHBondContact OE1-N 3.27Å; E428-R430 IonicContact OE1-NE 3.62Å; E428-R430 PolarHBondContact OE1-NE 3.4Å; E428-R430 IonicContact OE1-NH2 3.41Å; E428-R430 PolarHBondContact OE1-NH2 3.18Å; E428-R430 IonicContact OE2-CZ 3.7Å; E428-R430 IonicContact OE2-NE 3.55Å; E428-R430 IonicContact OE2-NH2 2.84Å; E428-R430 PolarHBondContact OE2-NH2 3.18Å; E428-K489 HydrophobicContact CG-CG 3.93Å; E428-K489 VanDerWaalsContact OE2-CG 3.3Å; E428-K489 WeakPolarHBondContact OE2-CG 3.38Å; E428-N715 WeakPolarHBondContact OE2-CB 3.33Å
429N92.3Very high88.6Confident63 Ų6330.8 Ų30.834%0.33716%0.158SC..  trans-94-2.5-175.3-64.9-58.8000113.5N427 G457 S458 G718 P721N427-N429 PolarHBondContact O-N 2.85Å; N427-N429 PolarHBondContact O-ND2 3.3Å; N429-G457 CarbonylContact O-C 3.41Å; N429-S458 PolarHBondContact O-N 3.49Å; N429-S458 VanDerWaalsContact O-N 3.17Å; N429-S458 PolarHBondContact O-OG 3.27Å; N429-G718 PolarHBondContact ND2-O 2.75Å; N429-P721 VanDerWaalsContact C-CB 3.5Å; N429-P721 HydrophobicContact CB-CB 3.63Å; N429-P721 HydrophobicContact CB-CG 3.62Å; N429-P721 VanDerWaalsContact O-CB 3.32Å; N429-P721 WeakPolarHBondContact O-CB 3.18Å
430R96.7Very high89.7Confident8 Ų832 Ų323%0.0317%0.171CC..  trans-74.2161.7176.7-66.7172.8-68169.4-3.4110.8E428 V488 M547 P721 A724 T725E428-R430 VanDerWaalsContact CD-NH2 3.31Å; E428-R430 WeakPolarHBondContact OE1-CB 3.39Å; E428-R430 WeakPolarHBondContact OE1-CG 3.48Å; E428-R430 IonicContact OE1-CZ 3.54Å; E428-R430 PolarHBondContact OE1-N 3.27Å; E428-R430 IonicContact OE1-NE 3.62Å; E428-R430 PolarHBondContact OE1-NE 3.4Å; E428-R430 IonicContact OE1-NH2 3.41Å; E428-R430 PolarHBondContact OE1-NH2 3.18Å; E428-R430 IonicContact OE2-CZ 3.7Å; E428-R430 IonicContact OE2-NE 3.55Å; E428-R430 IonicContact OE2-NH2 2.84Å; E428-R430 PolarHBondContact OE2-NH2 3.18Å; R430-V488 HydrophobicContact CB-CG1 4.16Å; R430-V488 HydrophobicContact CB-CG2 3.93Å; R430-V488 VanDerWaalsContact CZ-CG1 3.47Å; R430-M547 PolarHBondContact NH1-SD 2.92Å; R430-P721 HydrophobicContact CG-CB 4.14Å; R430-A724 VanDerWaalsContact CD-CB 3.42Å; R430-A724 HydrophobicContact CG-CB 3.91Å; R430-T725 WeakPolarHBondContact CA-OG1 3.15Å
431V96.7Very high90.7Very high3 Ų332 Ų322%0.01817%0.171CC..  trans-132.4147.2170.563.80000109.2I420 L433 A454 I460 Y465 T725I420-V431 HydrophobicContact CG2-CG2 3.55Å; V431-L433 VanDerWaalsContact C-N 3.32Å; V431-L433 PolarHBondContact O-N 2.98Å; V431-A454 HydrophobicContact CG2-CB 4.36Å; V431-I460 HydrophobicContact CG1-CD1 4.05Å; V431-Y465 VanDerWaalsContact CG1-OH 3.32Å; V431-Y465 WeakPolarHBondContact CG1-OH 3.3Å; V431-Y465 WeakPolarHBondContact CG2-OH 3.49Å; V431-T725 HydrophobicContact CG1-CG2 3.61Å; V431-T725 PolarHBondContact N-OG1 3.15Å; V431-T725 VanDerWaalsContact N-OG1 3.14Å; V431-T725 WeakPolarHBondContact O-CG2 3.33Å
432A96.4Very high91.6Very high4 Ų433.5 Ų33.53%0.03318%0.18CC..SBendtrans-68.9-30.4-172.900000113.2L486 V488A432-L486 HydrophobicContact CB-CB 3.85Å; A432-V488 HydrophobicContact CB-CG2 4.29Å
433L95.3Very high91.5Very high0 Ų034.3 Ų34.30%019%0.188CC..  trans-137.6116.4-177.4-154.772.3000111.1I420 V431 V438 L441 V448 Y465 L486 M733I420-L433 HydrophobicContact CD1-CB 3.56Å; I420-L433 HydrophobicContact CD1-CD2 3.8Å; I420-L433 HydrophobicContact CD1-CG 4.29Å; I420-L433 HydrophobicContact CG1-CB 4.03Å; V431-L433 VanDerWaalsContact C-N 3.32Å; V431-L433 PolarHBondContact O-N 2.98Å; L433-V438 HydrophobicContact CD2-CG2 3.89Å; L433-V438 HydrophobicContact CG-CG2 4.29Å; L433-L441 HydrophobicContact CD2-CD1 3.7Å; L433-V448 HydrophobicContact CD2-CG1 4.41Å; L433-Y465 WeakPolarHBondContact O-CE1 3.49Å; L433-Y465 PolarHBondContact O-OH 2.91Å; L433-L486 HydrophobicContact CD1-CD1 4.39Å; L433-L486 HydrophobicContact CD2-CD1 4.32Å; L433-M733 HydrophobicContact CD1-SD 3.95Å
434P96.5Very high91.2Very high0 Ų038 Ų380%021%0.208CC..  trans-80.4171.6169.632.9-32.5000111.4S436 G437 V438 I460 T725 Y726 S729P434-S436 PolarHBondContact O-N 3.09Å; P434-G437 PolarHBondContact O-N 3.15Å; P434-V438 PolarHBondContact O-N 3.18Å; P434-I460 HydrophobicContact CB-CD1 3.95Å; P434-T725 HydrophobicContact CB-CG2 4.02Å; P434-T725 HydrophobicContact CG-CG2 4.26Å; P434-Y726 HydrophobicContact CB-CD1 4.14Å; P434-Y726 HydrophobicContact CB-CE1 3.72Å; P434-Y726 HydrophobicContact CG-CD1 3.92Å; P434-Y726 HydrophobicContact CG-CE1 3.96Å; P434-S729 WeakPolarHBondContact CD-OG 3.4Å
435P95.9Very high90.8Very high22 Ų2238 Ų3814%0.14323%0.225CC..Hα-helixtrans-52.2-32.5-178.6-3136.8000114.7G437 V438 F439 I460 E464 A468P435-G437 PolarHBondContact O-N 2.6Å; P435-V438 PolarHBondContact O-N 2.83Å; P435-F439 WeakPolarHBondContact O-CB 2.94Å; P435-F439 PolarHBondContact O-N 3.24Å; P435-I460 HydrophobicContact CG-CG2 3.62Å; P435-E464 HydrophobicContact CG-CB 4.17Å; P435-A468 HydrophobicContact CB-CB 3.88Å; P435-A468 WeakPolarHBondContact O-CB 3.32Å
436S92.7Very high90.9Very high66 Ų6637.2 Ų37.246%0.46222%0.222SC..Hα-helixtrans-63.6-38176.454.10000113.3P434 G440P434-S436 PolarHBondContact O-N 3.09Å; S436-G440 PolarHBondContact O-N 3.46Å
437G93.4Very high91.1Very high2 Ų236.4 Ų36.42%0.02122%0.215CC..Hα-helixtrans-75.5-36.9176.700000112.2P434 P435 G440 L441P434-G437 PolarHBondContact O-N 3.15Å; P435-G437 PolarHBondContact O-N 2.6Å; G437-G440 PolarHBondContact O-N 3.08Å; G437-L441 PolarHBondContact O-N 3.35Å
438V96Very high91.5Very high0 Ų033.6 Ų33.60%020%0.2CC..Hα-helixtrans-58-52.3173.1173.30000110I420 L433 P434 P435 G440 L441 T442 V448 Y465 A468 A470I420-V438 HydrophobicContact CD1-CG2 4.36Å; L433-V438 HydrophobicContact CD2-CG2 3.89Å; L433-V438 HydrophobicContact CG-CG2 4.29Å; P434-V438 PolarHBondContact O-N 3.18Å; P435-V438 PolarHBondContact O-N 2.83Å; V438-G440 VanDerWaalsContact C-N 3.25Å; V438-G440 PolarHBondContact O-N 2.72Å; V438-L441 PolarHBondContact O-N 3.01Å; V438-L441 VanDerWaalsContact O-N 3.13Å; V438-T442 HydrophobicContact CG1-CG2 4.14Å; V438-T442 WeakPolarHBondContact O-CG2 3.46Å; V438-T442 PolarHBondContact O-N 3.03Å; V438-T442 PolarHBondContact O-OG1 3.4Å; V438-T442 VanDerWaalsContact O-OG1 3.04Å; V438-V448 HydrophobicContact CG1-CB 4.29Å; V438-V448 HydrophobicContact CG1-CG1 4.31Å; V438-V448 HydrophobicContact CG2-CG1 4.14Å; V438-Y465 HydrophobicContact CG2-CD1 3.78Å; V438-Y465 HydrophobicContact CG2-CE1 3.83Å; V438-A468 HydrophobicContact CB-CB 4.04Å; V438-A468 HydrophobicContact CG1-CB 3.83Å; V438-A470 HydrophobicContact CG1-CB 3.64Å
439F91.9Very high91.5Very high120 Ų12033.4 Ų33.453%0.52620%0.199SC..Hα-helixtrans-57.4-38.3177-176.9-102000112.4P435 T442 N443 A468P435-F439 WeakPolarHBondContact O-CB 2.94Å; P435-F439 PolarHBondContact O-N 3.24Å; F439-T442 WeakPolarHBondContact CA-OG1 3.26Å; F439-T442 PolarHBondContact O-OG1 3.21Å; F439-N443 WeakPolarHBondContact CD1-ND2 3.16Å; F439-N443 WeakPolarHBondContact CE1-ND2 3.38Å; F439-N443 WeakPolarHBondContact CE2-ND2 3.47Å; F439-N443 WeakPolarHBondContact CZ-ND2 3.41Å; F439-N443 WeakPolarHBondContact O-CB 3.42Å; F439-N443 VanDerWaalsContact O-CG 3.26Å; F439-N443 PolarHBondContact O-N 3.36Å; F439-N443 VanDerWaalsContact O-N 3.12Å; F439-N443 PolarHBondContact O-ND2 3.33Å; F439-A468 WeakPolarHBondContact CA-O 3.37Å; F439-A468 HydrophobicContact CB-CB 4.33Å
440G88.1Confident91.7Very high26 Ų2630.4 Ų30.427%0.26818%0.183SC..Hα-helixtrans-61.5-47.2175.200000112.6S436 G437 V438 L444S436-G440 PolarHBondContact O-N 3.46Å; G437-G440 PolarHBondContact O-N 3.08Å; V438-G440 VanDerWaalsContact C-N 3.25Å; V438-G440 PolarHBondContact O-N 2.72Å; G440-L444 WeakPolarHBondContact O-CG 3.35Å; G440-L444 PolarHBondContact O-N 3.05Å
441L91.8Very high91.6Very high0 Ų031.3 Ų31.30%019%0.188CC..Hα-helixtrans-70.2-43179.7-73.1179.2000112.8T418 L433 G437 V438 N443 L444 G445 H446 V448 M733 V736 A740T418-L441 HydrophobicContact CG2-CD1 4.28Å; L433-L441 HydrophobicContact CD2-CD1 3.7Å; G437-L441 PolarHBondContact O-N 3.35Å; V438-L441 PolarHBondContact O-N 3.01Å; V438-L441 VanDerWaalsContact O-N 3.13Å; L441-N443 VanDerWaalsContact C-N 3.34Å; L441-N443 PolarHBondContact O-N 3.44Å; L441-L444 CarbonylContact O-C 3.49Å; L441-L444 WeakPolarHBondContact O-CB 3.37Å; L441-L444 PolarHBondContact O-N 3.44Å; L441-L444 VanDerWaalsContact O-N 3.07Å; L441-G445 PolarHBondContact O-N 2.95Å; L441-H446 HydrophobicContact CB-CB 4.13Å; L441-H446 WeakPolarHBondContact O-CB 3.39Å; L441-H446 PolarHBondContact O-CD2 2.92Å; L441-H446 PolarHBondContact O-N 3.1Å; L441-V448 HydrophobicContact CB-CG2 3.63Å; L441-V448 HydrophobicContact CD1-CG2 3.95Å; L441-V448 HydrophobicContact CG-CG2 4.46Å; L441-M733 HydrophobicContact CD1-CE 4.48Å; L441-M733 HydrophobicContact CD2-CE 3.91Å; L441-M733 HydrophobicContact CG-CE 3.84Å; L441-V736 HydrophobicContact CD1-CG1 3.96Å; L441-V736 HydrophobicContact CD2-CG1 4.15Å; L441-V736 HydrophobicContact CG-CG1 4.47Å; L441-A740 HydrophobicContact CD2-CB 4.13Å
442T89.9Confident91.5Very high33 Ų3333.2 Ų33.220%0.20220%0.2CC..Hα-helixtrans-65.4-37.7-179.355.40000111.7V438 F439 L444 G445 H446 V448 A468 G469V438-T442 HydrophobicContact CG1-CG2 4.14Å; V438-T442 WeakPolarHBondContact O-CG2 3.46Å; V438-T442 PolarHBondContact O-N 3.03Å; V438-T442 PolarHBondContact O-OG1 3.4Å; V438-T442 VanDerWaalsContact O-OG1 3.04Å; F439-T442 WeakPolarHBondContact CA-OG1 3.26Å; F439-T442 PolarHBondContact O-OG1 3.21Å; T442-L444 PolarHBondContact O-N 3.24Å; T442-G445 PolarHBondContact O-N 3.48Å; T442-H446 WeakPolarHBondContact CA-O 3.37Å; T442-V448 HydrophobicContact CG2-CB 4.36Å; T442-V448 HydrophobicContact CG2-CG2 3.97Å; T442-A468 PolarHBondContact OG1-O 3.03Å; T442-A468 VanDerWaalsContact OG1-O 3.12Å; T442-G469 WeakPolarHBondContact CG2-O 3.32Å
443N84.8Confident91.4Very high106 Ų10638.7 Ų38.757%0.56722%0.223SC*.Hα-helixtrans-66.5-23.5172.6-76.7-38.6000114.2F439 L441F439-N443 WeakPolarHBondContact CD1-ND2 3.16Å; F439-N443 WeakPolarHBondContact CE1-ND2 3.38Å; F439-N443 WeakPolarHBondContact CE2-ND2 3.47Å; F439-N443 WeakPolarHBondContact CZ-ND2 3.41Å; F439-N443 WeakPolarHBondContact O-CB 3.42Å; F439-N443 VanDerWaalsContact O-CG 3.26Å; F439-N443 PolarHBondContact O-N 3.36Å; F439-N443 VanDerWaalsContact O-N 3.12Å; F439-N443 PolarHBondContact O-ND2 3.33Å; L441-N443 VanDerWaalsContact C-N 3.34Å; L441-N443 PolarHBondContact O-N 3.44Å
444L83.8Confident91.4Very high93 Ų9339 Ų3949%0.48723%0.225SC..THydrogen-bonded Turntrans-85.32.5173-68.4172.9000112.5G440 L441 T442G440-L444 WeakPolarHBondContact O-CG 3.35Å; G440-L444 PolarHBondContact O-N 3.05Å; L441-L444 CarbonylContact O-C 3.49Å; L441-L444 WeakPolarHBondContact O-CB 3.37Å; L441-L444 PolarHBondContact O-N 3.44Å; L441-L444 VanDerWaalsContact O-N 3.07Å; T442-L444 PolarHBondContact O-N 3.24Å
445G82.6Confident91.3Very high67 Ų6739 Ų3969%0.69123%0.225SC*.THydrogen-bonded Turntrans90.75.417800000114.7L441 T442L441-G445 PolarHBondContact O-N 2.95Å; T442-G445 PolarHBondContact O-N 3.48Å
446H87.2Confident91.3Very high29 Ų2942.9 Ų42.913%0.13424%0.244CC..  trans-81.7136.7177.2-60.8-67.2000110.9L441 T442 A740 N741L441-H446 HydrophobicContact CB-CB 4.13Å; L441-H446 WeakPolarHBondContact O-CB 3.39Å; L441-H446 PolarHBondContact O-CD2 2.92Å; L441-H446 PolarHBondContact O-N 3.1Å; T442-H446 WeakPolarHBondContact CA-O 3.37Å; H446-A740 PolarHBondContact CE1-O 3.42Å; H446-N741 PolarHBondContact NE2-OD1 3.43Å
447K84.6Confident91.3Very high54 Ų5441.3 Ų41.324%0.23524%0.238CC..  trans-83.3128.7166.8-154.3179.7179.7162.10108.4S416 L449S416-K447 VanDerWaalsContact CB-N 3.29Å; K447-L449 HydrophobicContact CD-CD2 3.86Å; K447-L449 HydrophobicContact CG-CD2 3.8Å
448V92.6Very high91.4Very high0 Ų041.3 Ų41.30%024%0.238CC..EExtended strand (participates in β ladder)trans-110.9120.5178-177.10000108.1T418 I420 L433 V438 L441 T442 V450 A470 T471T418-V448 WeakPolarHBondContact O-CA 3.27Å; I420-V448 HydrophobicContact CD1-CG1 3.51Å; L433-V448 HydrophobicContact CD2-CG1 4.41Å; V438-V448 HydrophobicContact CG1-CB 4.29Å; V438-V448 HydrophobicContact CG1-CG1 4.31Å; V438-V448 HydrophobicContact CG2-CG1 4.14Å; L441-V448 HydrophobicContact CB-CG2 3.63Å; L441-V448 HydrophobicContact CD1-CG2 3.95Å; L441-V448 HydrophobicContact CG-CG2 4.46Å; T442-V448 HydrophobicContact CG2-CB 4.36Å; T442-V448 HydrophobicContact CG2-CG2 3.97Å; V448-V450 HydrophobicContact CG1-CG2 4.26Å; V448-A470 HydrophobicContact CB-CB 4.5Å; V448-A470 HydrophobicContact CG1-CB 4.48Å; V448-A470 CarbonylContact O-C 3.01Å; V448-A470 VanDerWaalsContact O-CA 3.31Å; V448-A470 WeakPolarHBondContact O-CA 3.3Å; V448-T471 PolarHBondContact O-N 2.65Å
449L93Very high91.4Very high6 Ų645 Ų453%0.03127%0.268CS..EExtended strand (participates in β ladder)trans-108132.3176.3-31170000110.2T418 R419 I420 K447 T471 V473T418-L449 PolarHBondContact O-N 3.29Å; R419-L449 CarbonylContact C-O 3.45Å; R419-L449 WeakPolarHBondContact CA-O 3.41Å; R419-L449 HydrophobicContact CB-CB 4.33Å; R419-L449 HydrophobicContact CG-CB 3.62Å; R419-L449 HydrophobicContact CG-CD1 3.63Å; R419-L449 HydrophobicContact CG-CG 3.76Å; R419-L449 VanDerWaalsContact NE-CD1 3.34Å; I420-L449 PolarHBondContact N-O 3.38Å; K447-L449 HydrophobicContact CD-CD2 3.86Å; K447-L449 HydrophobicContact CG-CD2 3.8Å; L449-T471 CarbonylContact C-O 3.54Å; L449-T471 VanDerWaalsContact CA-O 3.27Å; L449-T471 WeakPolarHBondContact CA-O 3.31Å; L449-T471 HydrophobicContact CD2-CG2 4.2Å; L449-V473 HydrophobicContact CB-CG1 3.88Å
450V95.5Very high91.6Very high0 Ų039.4 Ų39.40%024%0.244CC..EExtended strand (participates in β ladder)trans-122.4126.5-174179.80000108.3I420 V448 T452 A454 Y465 A470 T471 I472 V473I420-V450 HydrophobicContact CB-CG2 4.33Å; I420-V450 HydrophobicContact CD1-CG2 3.69Å; V448-V450 HydrophobicContact CG1-CG2 4.26Å; V450-T452 PolarHBondContact O-N 2.78Å; V450-A454 HydrophobicContact CG1-CB 3.86Å; V450-Y465 HydrophobicContact CB-CD1 4.49Å; V450-Y465 HydrophobicContact CB-CG 4.44Å; V450-Y465 HydrophobicContact CG1-CD1 4.2Å; V450-Y465 HydrophobicContact CG1-CD2 3.88Å; V450-Y465 HydrophobicContact CG1-CE1 4.25Å; V450-Y465 HydrophobicContact CG1-CE2 3.9Å; V450-Y465 HydrophobicContact CG1-CG 4.03Å; V450-Y465 HydrophobicContact CG2-CD1 3.77Å; V450-Y465 HydrophobicContact CG2-CE1 4.09Å; V450-Y465 HydrophobicContact CG2-CG 4.17Å; V450-A470 HydrophobicContact CB-CB 4.5Å; V450-A470 HydrophobicContact CG2-CB 3.66Å; V450-T471 PolarHBondContact N-O 3.26Å; V450-I472 HydrophobicContact CB-CD1 4.1Å; V450-I472 HydrophobicContact CG1-CD1 4.4Å; V450-I472 CarbonylContact O-C 3.34Å; V450-I472 WeakPolarHBondContact O-CA 3.48Å; V450-V473 WeakPolarHBondContact O-CG2 3.46Å; V450-V473 PolarHBondContact O-N 3.28Å
451E95.1Very high92.1Very high26 Ų2641 Ų4112%0.12125%0.248CC..EExtended strand (participates in β ladder)trans-59.1135.5171.6-171.3178.7159.300110I420 K422 K453 A454 A476 A479I420-E451 PolarHBondContact O-N 2.84Å; K422-E451 HydrophobicContact CB-CB 4.3Å; K422-E451 VanDerWaalsContact CB-CD 3.44Å; K422-E451 HydrophobicContact CB-CG 4.19Å; K422-E451 WeakPolarHBondContact CB-OE2 3.46Å; K422-E451 PolarHBondContact N-OE2 2.95Å; E451-K453 PolarHBondContact O-N 2.95Å; E451-A454 HydrophobicContact CB-CB 4.33Å; E451-A454 WeakPolarHBondContact O-CB 3.36Å; E451-A454 PolarHBondContact O-N 2.84Å; E451-A476 WeakPolarHBondContact OE2-CA 3.49Å; E451-A479 HydrophobicContact CB-CB 3.77Å
452T94.3Very high92.4Very high44 Ų4442.7 Ų42.727%0.2726%0.257SS..THydrogen-bonded Turntrans-50.9132.6176.1-177.50000111V450 A454 D462 V473 P474V450-T452 PolarHBondContact O-N 2.78Å; T452-A454 PolarHBondContact O-N 3.02Å; T452-D462 WeakPolarHBondContact CA-OD2 3.43Å; T452-D462 WeakPolarHBondContact CB-OD2 3.12Å; T452-D462 PolarHBondContact OG1-OD2 2.87Å; T452-V473 PolarHBondContact N-O 2.75Å; T452-P474 WeakPolarHBondContact CG2-O 3.34Å
453K94.7Very high92.7Very high119 Ų11947.4 Ų47.452%0.51728%0.275SS..THydrogen-bonded Turntrans63.318.6-178.1-51.6172.2-176.3174.10114.7E451 G455 L456 D462E451-K453 PolarHBondContact O-N 2.95Å; K453-G455 VanDerWaalsContact C-N 3.34Å; K453-G455 PolarHBondContact O-N 3.09Å; K453-L456 HydrophobicContact CB-CB 4.26Å; K453-L456 HydrophobicContact CB-CD2 4.4Å; K453-L456 PolarHBondContact O-N 2.88Å; K453-D462 WeakPolarHBondContact CA-OD1 3.14Å; K453-D462 PolarHBondContact N-OD1 2.81Å; K453-D462 PolarHBondContact N-OD2 3.45Å
454A94.9Very high93.3Very high7 Ų745.7 Ų45.76%0.05826%0.264CS..THydrogen-bonded Turntrans-59.5-41.8176.300000112.7K422 V431 V450 E451 T452K422-A454 HydrophobicContact CB-CB 4.2Å; V431-A454 HydrophobicContact CG2-CB 4.36Å; V450-A454 HydrophobicContact CG1-CB 3.86Å; E451-A454 HydrophobicContact CB-CB 4.33Å; E451-A454 WeakPolarHBondContact O-CB 3.36Å; E451-A454 PolarHBondContact O-N 2.84Å; T452-A454 PolarHBondContact O-N 3.02Å
455G95.6Very high94Very high0 Ų041.3 Ų41.30%024%0.241CC..THydrogen-bonded Turntrans-88.6-1-178.400000115.4K453 G457 S458 A459 I460K453-G455 VanDerWaalsContact C-N 3.34Å; K453-G455 PolarHBondContact O-N 3.09Å; G455-G457 VanDerWaalsContact C-N 3.26Å; G455-G457 PolarHBondContact O-N 3.3Å; G455-S458 CarbonylContact O-C 3.57Å; G455-S458 WeakPolarHBondContact O-CA 3.36Å; G455-S458 WeakPolarHBondContact O-CB 3.34Å; G455-S458 PolarHBondContact O-N 3.24Å; G455-A459 PolarHBondContact O-N 2.81Å; G455-I460 CarbonylContact C-O 3.18Å; G455-I460 PolarHBondContact O-N 2.82Å
456L95.1Very high94.6Very high103 Ų10343.4 Ų43.454%0.53923%0.233SC..G310 helixtrans-60.8-36.4-170.5-17066.9000112.2K453 S458 A459 I460K453-L456 HydrophobicContact CB-CB 4.26Å; K453-L456 HydrophobicContact CB-CD2 4.4Å; K453-L456 PolarHBondContact O-N 2.88Å; L456-S458 PolarHBondContact O-N 2.93Å; L456-A459 PolarHBondContact O-N 2.94Å; L456-I460 WeakPolarHBondContact CA-O 3.29Å; L456-I460 PolarHBondContact N-O 3.37Å
457G92.1Very high95.1Very high32 Ų3248.1 Ų48.133%0.3326%0.255SS..G310 helixtrans-64-26.5174.500000113.6N429 G455 A459 P721N429-G457 CarbonylContact O-C 3.41Å; G455-G457 VanDerWaalsContact C-N 3.26Å; G455-G457 PolarHBondContact O-N 3.3Å; G457-A459 VanDerWaalsContact C-N 3.31Å; G457-P721 WeakPolarHBondContact O-CG 2.87Å
458S95.4Very high95.6Very high3 Ų346 Ų462%0.02125%0.248CC..G310 helixtrans-91.511.6174.3-620000113.2N429 G455 L456 I460 T725N429-S458 PolarHBondContact O-N 3.49Å; N429-S458 VanDerWaalsContact O-N 3.17Å; N429-S458 PolarHBondContact O-OG 3.27Å; G455-S458 CarbonylContact O-C 3.57Å; G455-S458 WeakPolarHBondContact O-CA 3.36Å; G455-S458 WeakPolarHBondContact O-CB 3.34Å; G455-S458 PolarHBondContact O-N 3.24Å; L456-S458 PolarHBondContact O-N 2.93Å; S458-I460 VanDerWaalsContact C-N 3.28Å; S458-I460 PolarHBondContact O-N 3.04Å; S458-T725 PolarHBondContact OG-OG1 3Å
459A96.3Very high95.6Very high77 Ų7748 Ų4864%0.63627%0.268SS*.THydrogen-bonded Turntrans57.836.7-172.200000113.7G455 L456 G457G455-A459 PolarHBondContact O-N 2.81Å; L456-A459 PolarHBondContact O-N 2.94Å; G457-A459 VanDerWaalsContact C-N 3.31Å
460I97.1Very high95.6Very high2 Ų248.2 Ų48.21%0.0127%0.27CS..  trans-114.3121.2175-59159.4000108.1V431 P434 P435 G455 L456 S458 E464 Y465 T725V431-I460 HydrophobicContact CG1-CD1 4.05Å; P434-I460 HydrophobicContact CB-CD1 3.95Å; P435-I460 HydrophobicContact CG-CG2 3.62Å; G455-I460 CarbonylContact C-O 3.18Å; G455-I460 PolarHBondContact O-N 2.82Å; L456-I460 WeakPolarHBondContact CA-O 3.29Å; L456-I460 PolarHBondContact N-O 3.37Å; S458-I460 VanDerWaalsContact C-N 3.28Å; S458-I460 PolarHBondContact O-N 3.04Å; I460-E464 HydrophobicContact CG2-CB 4.24Å; I460-Y465 HydrophobicContact CB-CE2 4.24Å; I460-Y465 HydrophobicContact CG2-CD2 3.8Å; I460-Y465 HydrophobicContact CG2-CE1 4.42Å; I460-Y465 HydrophobicContact CG2-CE2 3.43Å; I460-Y465 VanDerWaalsContact CG2-CE2 3.43Å; I460-Y465 HydrophobicContact CG2-CG 4.43Å; I460-T725 HydrophobicContact CD1-CG2 4.31Å
461T97.5Very high95.5Very high59 Ų5951 Ų5136%0.36229%0.288SS..  trans-85.2157.3-179.861.90000112.6K463 E464 Y465T461-K463 PolarHBondContact O-N 3.06Å; T461-E464 WeakPolarHBondContact CB-OE2 3.15Å; T461-E464 WeakPolarHBondContact CG2-OE2 3.29Å; T461-E464 PolarHBondContact N-OE2 3.32Å; T461-E464 PolarHBondContact O-N 3.42Å; T461-E464 VanDerWaalsContact O-N 3.07Å; T461-E464 WeakPolarHBondContact OG1-CG 3.39Å; T461-E464 PolarHBondContact OG1-N 2.93Å; T461-E464 PolarHBondContact OG1-OE2 2.95Å; T461-Y465 WeakPolarHBondContact O-CD2 3.43Å; T461-Y465 PolarHBondContact O-N 3Å
462D97.8Very high95.5Very high36 Ų3651.7 Ų51.719%0.19329%0.292CS..Hα-helixtrans-54.8-36.5171.9-71.77.4000111.2T452 K453 E464 Y465 E466 I472T452-D462 WeakPolarHBondContact CA-OD2 3.43Å; T452-D462 WeakPolarHBondContact CB-OD2 3.12Å; T452-D462 PolarHBondContact OG1-OD2 2.87Å; K453-D462 WeakPolarHBondContact CA-OD1 3.14Å; K453-D462 PolarHBondContact N-OD1 2.81Å; K453-D462 PolarHBondContact N-OD2 3.45Å; D462-E464 PolarHBondContact O-N 3.37Å; D462-Y465 WeakPolarHBondContact O-CB 3.48Å; D462-Y465 PolarHBondContact O-N 3.07Å; D462-E466 WeakPolarHBondContact O-CG 3.2Å; D462-E466 PolarHBondContact O-N 3.32Å; D462-I472 HydrophobicContact CB-CD1 3.96Å; D462-I472 HydrophobicContact CB-CG1 4.07Å
463K97.1Very high95.3Very high132 Ų13250.2 Ų50.257%0.57428%0.282SS*.Hα-helixtrans-61.7-43.1176.1-169.8-175.8-177.2-114.10112.5T461 Y465 E466 E467T461-K463 PolarHBondContact O-N 3.06Å; K463-Y465 VanDerWaalsContact C-N 3.26Å; K463-Y465 PolarHBondContact O-N 3.05Å; K463-E466 PolarHBondContact O-N 3.46Å; K463-E467 VanDerWaalsContact CE-OE1 3.23Å; K463-E467 WeakPolarHBondContact CE-OE1 3.4Å; K463-E467 IonicContact NZ-OE1 2.92Å; K463-E467 PolarHBondContact NZ-OE1 2.66Å; K463-E467 WeakPolarHBondContact O-CB 3.38Å; K463-E467 VanDerWaalsContact O-CG 3.29Å; K463-E467 WeakPolarHBondContact O-CG 3.5Å; K463-E467 PolarHBondContact O-N 2.7Å
464E97.4Very high94.8Very high71 Ų7149 Ų4933%0.33229%0.287SS..Hα-helixtrans-65.5-32.1177.2-73.5164.888.700111.9P435 I460 T461 D462 A468P435-E464 HydrophobicContact CG-CB 4.17Å; I460-E464 HydrophobicContact CG2-CB 4.24Å; T461-E464 WeakPolarHBondContact CB-OE2 3.15Å; T461-E464 WeakPolarHBondContact CG2-OE2 3.29Å; T461-E464 PolarHBondContact N-OE2 3.32Å; T461-E464 PolarHBondContact O-N 3.42Å; T461-E464 VanDerWaalsContact O-N 3.07Å; T461-E464 WeakPolarHBondContact OG1-CG 3.39Å; T461-E464 PolarHBondContact OG1-N 2.93Å; T461-E464 PolarHBondContact OG1-OE2 2.95Å; D462-E464 PolarHBondContact O-N 3.37Å; E464-A468 PolarHBondContact O-N 2.98Å
465Y97.9Very high94.1Very high0 Ų051.6 Ų51.60%030%0.3CS..Hα-helixtrans-66.5-46.7171.5-83.4-62.7000112.2V431 L433 V438 V450 I460 T461 D462 K463 E467 A468 G469 A470V431-Y465 VanDerWaalsContact CG1-OH 3.32Å; V431-Y465 WeakPolarHBondContact CG1-OH 3.3Å; V431-Y465 WeakPolarHBondContact CG2-OH 3.49Å; L433-Y465 WeakPolarHBondContact O-CE1 3.49Å; L433-Y465 PolarHBondContact O-OH 2.91Å; V438-Y465 HydrophobicContact CG2-CD1 3.78Å; V438-Y465 HydrophobicContact CG2-CE1 3.83Å; V450-Y465 HydrophobicContact CB-CD1 4.49Å; V450-Y465 HydrophobicContact CB-CG 4.44Å; V450-Y465 HydrophobicContact CG1-CD1 4.2Å; V450-Y465 HydrophobicContact CG1-CD2 3.88Å; V450-Y465 HydrophobicContact CG1-CE1 4.25Å; V450-Y465 HydrophobicContact CG1-CE2 3.9Å; V450-Y465 HydrophobicContact CG1-CG 4.03Å; V450-Y465 HydrophobicContact CG2-CD1 3.77Å; V450-Y465 HydrophobicContact CG2-CE1 4.09Å; V450-Y465 HydrophobicContact CG2-CG 4.17Å; I460-Y465 HydrophobicContact CB-CE2 4.24Å; I460-Y465 HydrophobicContact CG2-CD2 3.8Å; I460-Y465 HydrophobicContact CG2-CE1 4.42Å; I460-Y465 HydrophobicContact CG2-CE2 3.43Å; I460-Y465 VanDerWaalsContact CG2-CE2 3.43Å; I460-Y465 HydrophobicContact CG2-CG 4.43Å; T461-Y465 WeakPolarHBondContact O-CD2 3.43Å; T461-Y465 PolarHBondContact O-N 3Å; D462-Y465 WeakPolarHBondContact O-CB 3.48Å; D462-Y465 PolarHBondContact O-N 3.07Å; K463-Y465 VanDerWaalsContact C-N 3.26Å; K463-Y465 PolarHBondContact O-N 3.05Å; Y465-E467 VanDerWaalsContact C-N 3.34Å; Y465-E467 PolarHBondContact O-N 2.71Å; Y465-A468 PolarHBondContact O-N 3.42Å; Y465-G469 PolarHBondContact O-N 2.95Å; Y465-A470 WeakPolarHBondContact O-CB 3.34Å; Y465-A470 PolarHBondContact O-N 3.34Å
466E96.2Very high93.7Very high112 Ų11252.6 Ų52.652%0.52331%0.308SS..Hα-helixtrans-60.5-43.4175.8-68.6175.2143.700111.5D462 K463 A468 G469 I472D462-E466 WeakPolarHBondContact O-CG 3.2Å; D462-E466 PolarHBondContact O-N 3.32Å; K463-E466 PolarHBondContact O-N 3.46Å; E466-A468 PolarHBondContact O-N 2.92Å; E466-G469 WeakPolarHBondContact O-CA 3.48Å; E466-G469 PolarHBondContact O-N 3.39Å; E466-I472 HydrophobicContact CG-CD1 4.34Å; E466-I472 HydrophobicContact CG-CG1 3.59Å
467E96.8Very high93Very high128 Ų12852.4 Ų52.460%0.59831%0.306SS*.Hα-helixtrans-61.9-28.7176.6-74.9174.717900112.7K463 Y465 G469K463-E467 VanDerWaalsContact CE-OE1 3.23Å; K463-E467 WeakPolarHBondContact CE-OE1 3.4Å; K463-E467 IonicContact NZ-OE1 2.92Å; K463-E467 PolarHBondContact NZ-OE1 2.66Å; K463-E467 WeakPolarHBondContact O-CB 3.38Å; K463-E467 VanDerWaalsContact O-CG 3.29Å; K463-E467 WeakPolarHBondContact O-CG 3.5Å; K463-E467 PolarHBondContact O-N 2.7Å; Y465-E467 VanDerWaalsContact C-N 3.34Å; Y465-E467 PolarHBondContact O-N 2.71Å; E467-G469 VanDerWaalsContact C-N 3.32Å
468A95.3Very high92.6Very high10 Ų1052 Ų528%0.08330%0.297CS..THydrogen-bonded Turntrans-83.8-3.9172.700000114P435 V438 F439 T442 E464 Y465 E466P435-A468 HydrophobicContact CB-CB 3.88Å; P435-A468 WeakPolarHBondContact O-CB 3.32Å; V438-A468 HydrophobicContact CB-CB 4.04Å; V438-A468 HydrophobicContact CG1-CB 3.83Å; F439-A468 WeakPolarHBondContact CA-O 3.37Å; F439-A468 HydrophobicContact CB-CB 4.33Å; T442-A468 PolarHBondContact OG1-O 3.03Å; T442-A468 VanDerWaalsContact OG1-O 3.12Å; E464-A468 PolarHBondContact O-N 2.98Å; Y465-A468 PolarHBondContact O-N 3.42Å; E466-A468 PolarHBondContact O-N 2.92Å
469G92.1Very high92.2Very high42 Ų4251.8 Ų51.843%0.43330%0.296SS..THydrogen-bonded Turntrans97.99.7176.700000115.4T442 Y465 E466 E467T442-G469 WeakPolarHBondContact CG2-O 3.32Å; Y465-G469 PolarHBondContact O-N 2.95Å; E466-G469 WeakPolarHBondContact O-CA 3.48Å; E466-G469 PolarHBondContact O-N 3.39Å; E467-G469 VanDerWaalsContact C-N 3.32Å
470A94.1Very high92Very high9 Ų948.3 Ų48.37%0.07427%0.267CS..PPolyproline II helixtrans-73.3154.5172.200000111.8V438 V448 V450 Y465V438-A470 HydrophobicContact CG1-CB 3.64Å; V448-A470 HydrophobicContact CB-CB 4.5Å; V448-A470 HydrophobicContact CG1-CB 4.48Å; V448-A470 CarbonylContact O-C 3.01Å; V448-A470 VanDerWaalsContact O-CA 3.31Å; V448-A470 WeakPolarHBondContact O-CA 3.3Å; V450-A470 HydrophobicContact CB-CB 4.5Å; V450-A470 HydrophobicContact CG2-CB 3.66Å; Y465-A470 WeakPolarHBondContact O-CB 3.34Å; Y465-A470 PolarHBondContact O-N 3.34Å
471T93.7Very high91.3Very high60 Ų6049 Ų4937%0.36827%0.272SS..EExtended strand (participates in β ladder)trans-97.9122.3164.5-53.90000109.3V448 L449 V450V448-T471 PolarHBondContact O-N 2.65Å; L449-T471 CarbonylContact C-O 3.54Å; L449-T471 VanDerWaalsContact CA-O 3.27Å; L449-T471 WeakPolarHBondContact CA-O 3.31Å; L449-T471 HydrophobicContact CD2-CG2 4.2Å; V450-T471 PolarHBondContact N-O 3.26Å
472I94.4Very high90.8Very high40 Ų4046.1 Ų46.121%0.20526%0.255CS..EExtended strand (participates in β ladder)trans-75.2132.4174-55.3-59.9000109.8V450 D462 E466V450-I472 HydrophobicContact CB-CD1 4.1Å; V450-I472 HydrophobicContact CG1-CD1 4.4Å; V450-I472 CarbonylContact O-C 3.34Å; V450-I472 WeakPolarHBondContact O-CA 3.48Å; D462-I472 HydrophobicContact CB-CD1 3.96Å; D462-I472 HydrophobicContact CB-CG1 4.07Å; E466-I472 HydrophobicContact CG-CD1 4.34Å; E466-I472 HydrophobicContact CG-CG1 3.59Å
473V89.8Confident90.3Very high12 Ų1249.4 Ų49.47%0.07327%0.269CS..EExtended strand (participates in β ladder)trans-116.3148.6176.4-63.10000110.9L449 V450 T452 D475 A479L449-V473 HydrophobicContact CB-CG1 3.88Å; V450-V473 WeakPolarHBondContact O-CG2 3.46Å; V450-V473 PolarHBondContact O-N 3.28Å; T452-V473 PolarHBondContact N-O 2.75Å; V473-D475 PolarHBondContact O-N 3.29Å; V473-A479 HydrophobicContact CG2-CB 3.95Å
474P84.4Confident90.2Very high95 Ų9543.5 Ų43.562%0.61724%0.244SC*.SBendtrans-76.4-20.1-164.629.1-36.3000114.5T452T452-P474 WeakPolarHBondContact CG2-O 3.34Å
475D80.7Confident90.2Very high61 Ų6140.1 Ų40.133%0.32623%0.228SC..SBendtrans-153.1165.3-170.854.245.2000113.2V473 M477 S478 A479V473-D475 PolarHBondContact O-N 3.29Å; D475-M477 VanDerWaalsContact C-N 3.27Å; D475-M477 PolarHBondContact O-N 2.91Å; D475-M477 PolarHBondContact OD1-N 3.28Å; D475-S478 WeakPolarHBondContact O-CB 3.44Å; D475-S478 PolarHBondContact O-N 3Å; D475-S478 WeakPolarHBondContact OD1-CB 3.4Å; D475-S478 PolarHBondContact OD1-N 3.43Å; D475-S478 PolarHBondContact OD1-OG 2.97Å; D475-A479 PolarHBondContact O-N 3.46Å
476A86Confident90.2Very high21 Ų2140.2 Ų40.217%0.17423%0.228CC..Hα-helixtrans-58-37.1176.100000112.4E451 S478 A479 W480 Y498E451-A476 WeakPolarHBondContact OE2-CA 3.49Å; A476-S478 VanDerWaalsContact C-N 3.31Å; A476-S478 PolarHBondContact O-N 2.81Å; A476-A479 CarbonylContact O-C 3.55Å; A476-A479 WeakPolarHBondContact O-CA 3.37Å; A476-A479 PolarHBondContact O-N 2.88Å; A476-W480 WeakPolarHBondContact O-CB 3.33Å; A476-W480 PolarHBondContact O-N 2.96Å; A476-Y498 HydrophobicContact CB-CE2 4.26Å
477M81.9Confident90.2Very high99 Ų9934.9 Ų34.949%0.48820%0.203SC..Hα-helixtrans-59.2-46.9178.8-178.117870.600110.9D475 W480 A481 Y498D475-M477 VanDerWaalsContact C-N 3.27Å; D475-M477 PolarHBondContact O-N 2.91Å; D475-M477 PolarHBondContact OD1-N 3.28Å; M477-W480 PolarHBondContact O-N 2.79Å; M477-A481 PolarHBondContact O-N 2.98Å; M477-Y498 HydrophobicContact CB-CE1 3.9Å; M477-Y498 HydrophobicContact CG-CE1 4.28Å
478S82.4Confident90.2Very high22 Ų2228.8 Ų28.815%0.15418%0.175CC..Hα-helixtrans-59.5-50.3171-55.60000109.1R419 D475 A476 W480 A481R419-S478 WeakPolarHBondContact CD-O 3.42Å; R419-S478 PolarHBondContact NE-O 2.92Å; R419-S478 PolarHBondContact NH1-O 2.82Å; D475-S478 WeakPolarHBondContact O-CB 3.44Å; D475-S478 PolarHBondContact O-N 3Å; D475-S478 WeakPolarHBondContact OD1-CB 3.4Å; D475-S478 PolarHBondContact OD1-N 3.43Å; D475-S478 PolarHBondContact OD1-OG 2.97Å; A476-S478 VanDerWaalsContact C-N 3.31Å; A476-S478 PolarHBondContact O-N 2.81Å; S478-W480 PolarHBondContact O-N 2.75Å; S478-W480 VanDerWaalsContact O-N 3.15Å; S478-A481 PolarHBondContact O-N 3.2Å
479A87.7Confident90.2Very high0 Ų028.5 Ų28.50%017%0.172CC..Hα-helixtrans-66.5-14.4-179.500000115.7R419 P421 E451 V473 D475 A476R419-A479 WeakPolarHBondContact CB-O 3.4Å; R419-A479 VanDerWaalsContact CD-C 3.44Å; R419-A479 VanDerWaalsContact CD-O 3.29Å; R419-A479 WeakPolarHBondContact CD-O 3.36Å; P421-A479 HydrophobicContact CB-CB 3.94Å; E451-A479 HydrophobicContact CB-CB 3.77Å; V473-A479 HydrophobicContact CG2-CB 3.95Å; D475-A479 PolarHBondContact O-N 3.46Å; A476-A479 CarbonylContact O-C 3.55Å; A476-A479 WeakPolarHBondContact O-CA 3.37Å; A476-A479 PolarHBondContact O-N 2.88Å
480W91.5Very high90.3Very high3 Ų327.4 Ų27.41%0.01116%0.155CC..Hα-helixtrans-97.5-14.9177.9-85.789.4000114.2A476 M477 S478 A482 V485 K487 P491 E495 Y498 F499 R500 L503 L505A476-W480 WeakPolarHBondContact O-CB 3.33Å; A476-W480 PolarHBondContact O-N 2.96Å; M477-W480 PolarHBondContact O-N 2.79Å; S478-W480 PolarHBondContact O-N 2.75Å; S478-W480 VanDerWaalsContact O-N 3.15Å; W480-A482 PolarHBondContact O-N 3.35Å; W480-V485 HydrophobicContact CD2-CG1 4.35Å; W480-V485 HydrophobicContact CE3-CG1 4.13Å; W480-V485 HydrophobicContact CE3-CG2 4.11Å; W480-V485 HydrophobicContact CH2-CG1 4.48Å; W480-V485 HydrophobicContact CZ3-CG1 4.2Å; W480-K487 HydrophobicContact CH2-CD 3.67Å; W480-K487 HydrophobicContact CZ2-CD 3.35Å; W480-P491 HydrophobicContact CH2-CB 4.26Å; W480-P491 HydrophobicContact CH2-CG 4Å; W480-E495 HydrophobicContact CH2-CB 4.48Å; W480-E495 HydrophobicContact CZ2-CB 3.9Å; W480-E495 HydrophobicContact CZ2-CG 4.13Å; W480-E495 WeakPolarHBondContact CZ2-OE1 3.5Å; W480-Y498 HydrophobicContact CB-CD1 4.02Å; W480-Y498 HydrophobicContact CB-CD2 4.23Å; W480-Y498 HydrophobicContact CB-CG 3.73Å; W480-Y498 AromaticContact CD1-CD2 3.53Å; W480-Y498 AromaticContact CD1-CE2 3.84Å; W480-Y498 AromaticContact CD1-CG 3.95Å; W480-Y498 AromaticContact CD2-CD2 3.84Å; W480-Y498 HydrophobicContact CD2-CD2 3.84Å; W480-Y498 AromaticContact CD2-CG 3.96Å; W480-Y498 HydrophobicContact CD2-CG 3.96Å; W480-Y498 AromaticContact CE2-CD2 3.85Å; W480-Y498 HydrophobicContact CG-CD1 4.3Å; W480-Y498 AromaticContact CG-CD2 3.62Å; W480-Y498 HydrophobicContact CG-CD2 3.62Å; W480-Y498 HydrophobicContact CG-CE2 4.33Å; W480-Y498 AromaticContact CG-CG 3.61Å; W480-Y498 HydrophobicContact CG-CG 3.61Å; W480-Y498 AromaticContact NE1-CD2 3.66Å; W480-F499 HydrophobicContact CH2-CE1 4.07Å; W480-F499 HydrophobicContact CZ3-CD1 4.14Å; W480-F499 HydrophobicContact CZ3-CE1 4.02Å; W480-R500 PolarHBondContact O-NH1 3.06Å; W480-L503 HydrophobicContact CE3-CD2 4.08Å; W480-L503 HydrophobicContact CZ3-CD2 3.91Å; W480-L505 HydrophobicContact CH2-CD1 4.19Å; W480-L505 HydrophobicContact CZ3-CD1 4.22Å
481A82.9Confident90.4Very high16 Ų1627 Ų2713%0.13215%0.152CC..SBendtrans-73.229.9-179.600000114Y361 R419 M477 S478Y361-A481 HydrophobicContact CD2-CB 4.32Å; Y361-A481 HydrophobicContact CE2-CB 4.3Å; R419-A481 PolarHBondContact NE-O 3.04Å; R419-A481 PolarHBondContact NH2-O 3.02Å; M477-A481 PolarHBondContact O-N 2.98Å; S478-A481 PolarHBondContact O-N 3.2Å
482A85.9Confident90.4Very high0 Ų026.6 Ų26.60%015%0.147CC..SBendtrans-105.5136.2-173.200000110.9N417 R419 W480 M484 V485 R500 L503N417-A482 CarbonylContact O-C 3.15Å; N417-A482 VanDerWaalsContact O-C 3.23Å; N417-A482 VanDerWaalsContact O-CA 3.29Å; N417-A482 WeakPolarHBondContact O-CA 3.13Å; N417-A482 WeakPolarHBondContact O-CB 3.47Å; R419-A482 HydrophobicContact CB-CB 3.42Å; R419-A482 VanDerWaalsContact CB-CB 3.42Å; R419-A482 HydrophobicContact CG-CB 3.18Å; W480-A482 PolarHBondContact O-N 3.35Å; A482-M484 WeakPolarHBondContact CB-O 3.45Å; A482-M484 PolarHBondContact O-N 3.34Å; A482-V485 HydrophobicContact CB-CG2 3.86Å; A482-R500 VanDerWaalsContact O-CZ 3.3Å; A482-R500 PolarHBondContact O-NH1 2.61Å; A482-R500 PolarHBondContact O-NH2 2.91Å; A482-L503 WeakPolarHBondContact O-CD1 3.33Å
483E87.8Confident90.3Very high104 Ų10428.1 Ų28.149%0.48617%0.166SC..SBendtrans-47.6-45.6166.5-70170.6156.900111.6N417 L504N417-E483 HydrophobicContact CB-CB 3.52Å; N417-E483 HydrophobicContact CB-CG 3.39Å; N417-E483 WeakPolarHBondContact CB-OE2 3.16Å; N417-E483 PolarHBondContact ND2-OE1 3.5Å; N417-E483 PolarHBondContact ND2-OE2 3.43Å; N417-E483 PolarHBondContact O-N 3.07Å; E483-L504 WeakPolarHBondContact O-CB 3.33Å; E483-L504 PolarHBondContact O-N 3.46Å
484M95.4Very high90.4Very high8 Ų834.3 Ų34.34%0.03919%0.194CC..EExtended strand (participates in β ladder)trans-116.4120.7175.7-173.3175.365.600111.6N417 T418 R419 A482 L486 L504 V736 L739 A740N417-M484 PolarHBondContact O-N 3.03Å; T418-M484 WeakPolarHBondContact CA-O 2.86Å; T418-M484 HydrophobicContact CG2-CE 3.62Å; R419-M484 PolarHBondContact N-O 2.69Å; A482-M484 WeakPolarHBondContact CB-O 3.45Å; A482-M484 PolarHBondContact O-N 3.34Å; M484-L486 HydrophobicContact CE-CD2 4.06Å; M484-L486 HydrophobicContact CE-CG 4.41Å; M484-L486 HydrophobicContact CG-CD2 4.1Å; M484-L486 HydrophobicContact SD-CD2 4.03Å; M484-L504 WeakPolarHBondContact CA-O 3.31Å; M484-L504 HydrophobicContact CB-CD2 4.37Å; M484-L504 HydrophobicContact CG-CD2 4Å; M484-L504 HydrophobicContact CG-CG 4.2Å; M484-L504 HydrophobicContact SD-CD2 4.03Å; M484-V736 HydrophobicContact CE-CG1 4.08Å; M484-L739 HydrophobicContact SD-CB 3.8Å; M484-L739 HydrophobicContact SD-CD1 4.49Å; M484-A740 HydrophobicContact CE-CB 4.08Å
485V96.9Very high90.9Very high0 Ų030 Ų300%017%0.166CC..EExtended strand (participates in β ladder)trans-106.7123.7173.61730000109.8P421 W480 A482 K487 L503 L504 L505 F506P421-V485 HydrophobicContact CG-CG1 3.81Å; W480-V485 HydrophobicContact CD2-CG1 4.35Å; W480-V485 HydrophobicContact CE3-CG1 4.13Å; W480-V485 HydrophobicContact CE3-CG2 4.11Å; W480-V485 HydrophobicContact CH2-CG1 4.48Å; W480-V485 HydrophobicContact CZ3-CG1 4.2Å; A482-V485 HydrophobicContact CB-CG2 3.86Å; V485-K487 HydrophobicContact CG1-CD 4.3Å; V485-K487 HydrophobicContact CG1-CG 4.13Å; V485-L503 HydrophobicContact CB-CD1 3.9Å; V485-L503 HydrophobicContact CG2-CD1 3.52Å; V485-L504 PolarHBondContact N-O 2.92Å; V485-L505 HydrophobicContact CB-CD1 4.27Å; V485-L505 HydrophobicContact CG1-CD1 4.09Å; V485-F506 PolarHBondContact O-N 2.85Å
486L97.4Very high91.5Very high2 Ų229.8 Ų29.81%0.0116%0.161CC..EExtended strand (participates in β ladder)trans-100.5119.8174.9-56.6-178.4000109.6T418 R419 P421 A432 L433 M484 F506 V736T418-L486 HydrophobicContact CG2-CD1 4.35Å; R419-L486 PolarHBondContact O-N 2.75Å; P421-L486 WeakPolarHBondContact CD-O 3.37Å; A432-L486 HydrophobicContact CB-CB 3.85Å; L433-L486 HydrophobicContact CD1-CD1 4.39Å; L433-L486 HydrophobicContact CD2-CD1 4.32Å; M484-L486 HydrophobicContact CE-CD2 4.06Å; M484-L486 HydrophobicContact CE-CG 4.41Å; M484-L486 HydrophobicContact CG-CD2 4.1Å; M484-L486 HydrophobicContact SD-CD2 4.03Å; L486-F506 HydrophobicContact CD2-CB 4.09Å; L486-F506 HydrophobicContact CD2-CD1 3.94Å; L486-V736 HydrophobicContact CD1-CG1 3.85Å; L486-V736 HydrophobicContact CD1-CG2 4.18Å; L486-V736 HydrophobicContact CD2-CG1 4.47Å; L486-V736 HydrophobicContact CD2-CG2 4.03Å
487K97.7Very high91.8Very high0 Ų036.6 Ų36.60%018%0.182CC..  trans-127.9163.2175.7-84.1178.162.671.20111.1P421 E423 W480 V485 K489 E495 L505 F506 T507 Y531P421-K487 HydrophobicContact CG-CD 3.88Å; P421-K487 HydrophobicContact CG-CG 3.52Å; E423-K487 WeakPolarHBondContact OE1-CB 3.43Å; E423-K487 IonicContact OE1-NZ 3.37Å; E423-K487 PolarHBondContact OE1-NZ 3.07Å; E423-K487 IonicContact OE2-NZ 2.62Å; E423-K487 PolarHBondContact OE2-NZ 3.19Å; W480-K487 HydrophobicContact CH2-CD 3.67Å; W480-K487 HydrophobicContact CZ2-CD 3.35Å; V485-K487 HydrophobicContact CG1-CD 4.3Å; V485-K487 HydrophobicContact CG1-CG 4.13Å; K487-K489 VanDerWaalsContact CE-O 3.29Å; K487-K489 WeakPolarHBondContact CE-O 3.33Å; K487-E495 WeakPolarHBondContact CE-OE1 3.29Å; K487-E495 IonicContact NZ-OE1 2.7Å; K487-E495 PolarHBondContact NZ-OE1 3.08Å; K487-E495 IonicContact NZ-OE2 3.42Å; K487-L505 HydrophobicContact CD-CD1 4.45Å; K487-F506 PolarHBondContact N-O 3.39Å; K487-T507 VanDerWaalsContact C-OG1 3.22Å; K487-T507 HydrophobicContact CB-CG2 4.44Å; K487-T507 VanDerWaalsContact CB-OG1 3.26Å; K487-T507 WeakPolarHBondContact CB-OG1 3.47Å; K487-T507 PolarHBondContact O-OG1 3.44Å; K487-Y531 WeakPolarHBondContact O-CE2 3.49Å; K487-Y531 PolarHBondContact O-OH 3.12Å
488V96.6Very high92.2Very high0 Ų033.7 Ų33.70%017%0.166CC..SBendtrans-87-55.8168.3-176.70000109.5E423 R430 A432 T507 Y508 L728E423-V488 HydrophobicContact CG-CB 4.05Å; E423-V488 HydrophobicContact CG-CG2 4.17Å; E423-V488 WeakPolarHBondContact OE1-CA 3.47Å; E423-V488 PolarHBondContact OE1-N 3.34Å; R430-V488 HydrophobicContact CB-CG1 4.16Å; R430-V488 HydrophobicContact CB-CG2 3.93Å; R430-V488 VanDerWaalsContact CZ-CG1 3.47Å; A432-V488 HydrophobicContact CB-CG2 4.29Å; V488-T507 VanDerWaalsContact C-OG1 3.23Å; V488-T507 PolarHBondContact O-OG1 3.25Å; V488-Y508 WeakPolarHBondContact O-CB 3.29Å; V488-Y508 WeakPolarHBondContact O-CD2 3.42Å; V488-Y508 PolarHBondContact O-N 3.43Å; V488-L728 HydrophobicContact CG1-CD2 4.02Å; V488-L728 HydrophobicContact CG2-CD2 4.2Å
489K94.6Very high92.8Very high5 Ų533.7 Ų33.72%0.02216%0.163CC..SBendtrans-105.3168.8-173.1-66.7-60.7-71.1138.70112.9E423 K425 E428 K487 T507 Y508 H510E423-K489 PolarHBondContact OE1-N 3.06Å; K425-K489 HydrophobicContact CD-CB 4.31Å; K425-K489 HydrophobicContact CD-CG 4.25Å; E428-K489 HydrophobicContact CG-CG 3.93Å; E428-K489 VanDerWaalsContact OE2-CG 3.3Å; E428-K489 WeakPolarHBondContact OE2-CG 3.38Å; K487-K489 VanDerWaalsContact CE-O 3.29Å; K487-K489 WeakPolarHBondContact CE-O 3.33Å; K489-T507 PolarHBondContact N-OG1 3.42Å; K489-T507 PolarHBondContact O-OG1 2.94Å; K489-Y508 CarbonylContact C-O 3.6Å; K489-H510 PolarHBondContact NZ-CD2 3.25Å; K489-H510 VanDerWaalsContact NZ-CD2 3.3Å; K489-H510 PolarHBondContact NZ-NE2 2.89Å
490E94.1Very high93.1Very high18 Ų1835.2 Ų35.28%0.08417%0.169CC..PPolyproline II helixtrans-64.1142.717871.5-75.5177.700110.3K425 L492 Y508 L509 H510 L517K425-E490 IonicContact NZ-OE1 3.99Å; K425-E490 PolarHBondContact NZ-OE1 2.81Å; K425-E490 IonicContact NZ-OE2 3.66Å; E490-L492 PolarHBondContact O-N 3.27Å; E490-Y508 WeakPolarHBondContact CA-O 3.48Å; E490-Y508 WeakPolarHBondContact CB-O 3.49Å; E490-Y508 PolarHBondContact N-O 3.49Å; E490-L509 WeakPolarHBondContact CB-O 3.38Å; E490-H510 IonicContact OE2-CD2 3.17Å; E490-L517 HydrophobicContact CB-CD2 3.7Å; E490-L517 HydrophobicContact CG-CD2 4.17Å
491P95.9Very high93Very high1 Ų141.8 Ų41.81%0.00620%0.198CC..PPolyproline II helixtrans-60.3136.4177.4-2333.6000111.6W480 E495 Y496 F499 L505 L517W480-P491 HydrophobicContact CH2-CB 4.26Å; W480-P491 HydrophobicContact CH2-CG 4Å; P491-E495 VanDerWaalsContact CA-OE2 3.29Å; P491-E495 WeakPolarHBondContact CA-OE2 3.29Å; P491-E495 HydrophobicContact CB-CB 4.1Å; P491-Y496 HydrophobicContact CB-CD1 4.4Å; P491-Y496 HydrophobicContact CB-CE1 4.28Å; P491-Y496 WeakPolarHBondContact O-CE1 3.36Å; P491-F499 HydrophobicContact CB-CE1 3.85Å; P491-F499 HydrophobicContact CB-CZ 3.64Å; P491-F499 HydrophobicContact CG-CE1 3.82Å; P491-F499 HydrophobicContact CG-CZ 3.77Å; P491-L505 HydrophobicContact CG-CD2 3.68Å; P491-L517 HydrophobicContact CB-CD1 4.09Å; P491-L517 HydrophobicContact CG-CD1 4.19Å
492L94.1Very high93.2Very high51 Ų5145.4 Ų45.427%0.26722%0.215SC..PPolyproline II helixtrans-84.8167.5171.2-53.2-174.6000110.7I424 K425 E490 E494 E495 Y496I424-L492 HydrophobicContact CD1-CB 4.08Å; I424-L492 HydrophobicContact CD1-CD1 3.83Å; I424-L492 HydrophobicContact CD1-CG 4.15Å; I424-L492 HydrophobicContact CG1-CD1 3.8Å; I424-L492 HydrophobicContact CG1-CG 4.22Å; K425-L492 HydrophobicContact CB-CD1 4.46Å; E490-L492 PolarHBondContact O-N 3.27Å; L492-E494 PolarHBondContact O-N 3.1Å; L492-E494 VanDerWaalsContact O-N 3.09Å; L492-E495 PolarHBondContact N-OE2 3.22Å; L492-E495 WeakPolarHBondContact O-CB 3.39Å; L492-E495 PolarHBondContact O-N 3.45Å; L492-Y496 VanDerWaalsContact C-CE1 3.45Å; L492-Y496 WeakPolarHBondContact O-CD1 3.48Å; L492-Y496 WeakPolarHBondContact O-CE1 3.46Å; L492-Y496 PolarHBondContact O-N 3.38Å
493A92.6Very high93.5Very high73 Ų7345.4 Ų45.460%0.60322%0.215SC*.G310 helixtrans-53.9-34.7-177.600000113.5E495 Y496A493-E495 VanDerWaalsContact C-N 3.25Å; A493-E495 PolarHBondContact O-N 3.08Å; A493-Y496 HydrophobicContact CB-CD2 4.44Å; A493-Y496 HydrophobicContact CB-CE2 4.14Å; A493-Y496 WeakPolarHBondContact O-CB 3.38Å; A493-Y496 PolarHBondContact O-N 3.43Å
494E91.3Very high93.9Very high142 Ų14241.3 Ų41.366%0.66420%0.196SC*.G310 helixtrans-67.4-23.3178-63.2165.9-162.100113.4L492 R497L492-E494 PolarHBondContact O-N 3.1Å; L492-E494 VanDerWaalsContact O-N 3.09Å; E494-R497 WeakPolarHBondContact O-CG 3.36Å; E494-R497 PolarHBondContact O-NE 2.92Å
495E94.8Very high94.1Very high5 Ų540.9 Ų40.92%0.02319%0.194CC..G310 helixtrans-90.2-12.9179.5-66.9171.5113.600112.3I424 W480 K487 P491 L492 A493 R497 Y498I424-E495 VanDerWaalsContact CD1-CD 3.48Å; I424-E495 HydrophobicContact CD1-CG 3.56Å; I424-E495 HydrophobicContact CG1-CG 4.33Å; W480-E495 HydrophobicContact CH2-CB 4.48Å; W480-E495 HydrophobicContact CZ2-CB 3.9Å; W480-E495 HydrophobicContact CZ2-CG 4.13Å; W480-E495 WeakPolarHBondContact CZ2-OE1 3.5Å; K487-E495 WeakPolarHBondContact CE-OE1 3.29Å; K487-E495 IonicContact NZ-OE1 2.7Å; K487-E495 PolarHBondContact NZ-OE1 3.08Å; K487-E495 IonicContact NZ-OE2 3.42Å; P491-E495 VanDerWaalsContact CA-OE2 3.29Å; P491-E495 WeakPolarHBondContact CA-OE2 3.29Å; P491-E495 HydrophobicContact CB-CB 4.1Å; L492-E495 PolarHBondContact N-OE2 3.22Å; L492-E495 WeakPolarHBondContact O-CB 3.39Å; L492-E495 PolarHBondContact O-N 3.45Å; A493-E495 VanDerWaalsContact C-N 3.25Å; A493-E495 PolarHBondContact O-N 3.08Å; E495-R497 PolarHBondContact O-N 2.81Å; E495-R497 VanDerWaalsContact O-N 3.09Å; E495-Y498 HydrophobicContact CB-CD2 4.16Å; E495-Y498 HydrophobicContact CG-CD2 4.48Å; E495-Y498 WeakPolarHBondContact O-CB 3.29Å; E495-Y498 WeakPolarHBondContact O-CD2 3.46Å; E495-Y498 PolarHBondContact O-N 3.36Å
496Y94.8Very high94.1Very high55 Ų5540.9 Ų40.922%0.21619%0.194CC..G310 helixtrans-61.5-25.2-178-62.9-6000112.7P491 L492 A493 Y498 F499 L517 A520P491-Y496 HydrophobicContact CB-CD1 4.4Å; P491-Y496 HydrophobicContact CB-CE1 4.28Å; P491-Y496 WeakPolarHBondContact O-CE1 3.36Å; L492-Y496 VanDerWaalsContact C-CE1 3.45Å; L492-Y496 WeakPolarHBondContact O-CD1 3.48Å; L492-Y496 WeakPolarHBondContact O-CE1 3.46Å; L492-Y496 PolarHBondContact O-N 3.38Å; A493-Y496 HydrophobicContact CB-CD2 4.44Å; A493-Y496 HydrophobicContact CB-CE2 4.14Å; A493-Y496 WeakPolarHBondContact O-CB 3.38Å; A493-Y496 PolarHBondContact O-N 3.43Å; Y496-Y498 PolarHBondContact O-N 3.38Å; Y496-F499 HydrophobicContact CD1-CD2 4.45Å; Y496-F499 AromaticContact CD1-CE2 3.59Å; Y496-F499 HydrophobicContact CD1-CE2 3.59Å; Y496-F499 AromaticContact CD1-CZ 3.68Å; Y496-F499 HydrophobicContact CD1-CZ 3.68Å; Y496-F499 HydrophobicContact CE1-CE2 4.27Å; Y496-F499 HydrophobicContact CE1-CZ 4.25Å; Y496-F499 HydrophobicContact CG-CE2 4.06Å; Y496-F499 WeakPolarHBondContact O-CB 3.37Å; Y496-F499 WeakPolarHBondContact O-CG 3.47Å; Y496-F499 PolarHBondContact O-N 3.18Å; Y496-F499 VanDerWaalsContact O-N 3.15Å; Y496-L517 HydrophobicContact CD1-CD1 4.37Å; Y496-L517 HydrophobicContact CE1-CB 4.5Å; Y496-L517 HydrophobicContact CE1-CD1 3.59Å; Y496-L517 WeakPolarHBondContact OH-CA 3.46Å; Y496-L517 WeakPolarHBondContact OH-CB 3.44Å; Y496-L517 PolarHBondContact OH-N 2.73Å; Y496-A520 HydrophobicContact CD1-CB 4.22Å; Y496-A520 HydrophobicContact CD2-CB 3.53Å; Y496-A520 HydrophobicContact CE1-CB 4.46Å; Y496-A520 HydrophobicContact CE2-CB 3.79Å; Y496-A520 HydrophobicContact CG-CB 3.79Å
497R91.6Very high94.1Very high164 Ų16440.8 Ų40.862%0.61919%0.194SC*.G310 helixtrans-62.2-17.8175.470.2-175.5178.2-173.7-3.7113.9E494 E495E494-R497 WeakPolarHBondContact O-CG 3.36Å; E494-R497 PolarHBondContact O-NE 2.92Å; E495-R497 PolarHBondContact O-N 2.81Å; E495-R497 VanDerWaalsContact O-N 3.09Å
498Y90.1Very high94Very high38 Ų3841 Ų4115%0.14920%0.195CC..G310 helixtrans-92.6-6.1179.5-57.6-54.3000113.4A476 M477 W480 E495 Y496A476-Y498 HydrophobicContact CB-CE2 4.26Å; M477-Y498 HydrophobicContact CB-CE1 3.9Å; M477-Y498 HydrophobicContact CG-CE1 4.28Å; W480-Y498 HydrophobicContact CB-CD1 4.02Å; W480-Y498 HydrophobicContact CB-CD2 4.23Å; W480-Y498 HydrophobicContact CB-CG 3.73Å; W480-Y498 AromaticContact CD1-CD2 3.53Å; W480-Y498 AromaticContact CD1-CE2 3.84Å; W480-Y498 AromaticContact CD1-CG 3.95Å; W480-Y498 AromaticContact CD2-CD2 3.84Å; W480-Y498 HydrophobicContact CD2-CD2 3.84Å; W480-Y498 AromaticContact CD2-CG 3.96Å; W480-Y498 HydrophobicContact CD2-CG 3.96Å; W480-Y498 AromaticContact CE2-CD2 3.85Å; W480-Y498 HydrophobicContact CG-CD1 4.3Å; W480-Y498 AromaticContact CG-CD2 3.62Å; W480-Y498 HydrophobicContact CG-CD2 3.62Å; W480-Y498 HydrophobicContact CG-CE2 4.33Å; W480-Y498 AromaticContact CG-CG 3.61Å; W480-Y498 HydrophobicContact CG-CG 3.61Å; W480-Y498 AromaticContact NE1-CD2 3.66Å; E495-Y498 HydrophobicContact CB-CD2 4.16Å; E495-Y498 HydrophobicContact CG-CD2 4.48Å; E495-Y498 WeakPolarHBondContact O-CB 3.29Å; E495-Y498 WeakPolarHBondContact O-CD2 3.46Å; E495-Y498 PolarHBondContact O-N 3.36Å; Y496-Y498 PolarHBondContact O-N 3.38Å
499F95.4Very high93.9Very high22 Ų2241 Ų4110%0.09620%0.195CC..  trans-70.7139.3179.6-66.4-11.8000111.6W480 P491 Y496 L503 L517 A520 L521 A524 V526W480-F499 HydrophobicContact CH2-CE1 4.07Å; W480-F499 HydrophobicContact CZ3-CD1 4.14Å; W480-F499 HydrophobicContact CZ3-CE1 4.02Å; P491-F499 HydrophobicContact CB-CE1 3.85Å; P491-F499 HydrophobicContact CB-CZ 3.64Å; P491-F499 HydrophobicContact CG-CE1 3.82Å; P491-F499 HydrophobicContact CG-CZ 3.77Å; Y496-F499 HydrophobicContact CD1-CD2 4.45Å; Y496-F499 AromaticContact CD1-CE2 3.59Å; Y496-F499 HydrophobicContact CD1-CE2 3.59Å; Y496-F499 AromaticContact CD1-CZ 3.68Å; Y496-F499 HydrophobicContact CD1-CZ 3.68Å; Y496-F499 HydrophobicContact CE1-CE2 4.27Å; Y496-F499 HydrophobicContact CE1-CZ 4.25Å; Y496-F499 HydrophobicContact CG-CE2 4.06Å; Y496-F499 WeakPolarHBondContact O-CB 3.37Å; Y496-F499 WeakPolarHBondContact O-CG 3.47Å; Y496-F499 PolarHBondContact O-N 3.18Å; Y496-F499 VanDerWaalsContact O-N 3.15Å; F499-L503 HydrophobicContact CD1-CD2 4.46Å; F499-L517 HydrophobicContact CE2-CD1 4.2Å; F499-L517 HydrophobicContact CZ-CD1 3.91Å; F499-A520 HydrophobicContact CD2-CB 4.16Å; F499-A520 HydrophobicContact CE2-CB 3.82Å; F499-L521 HydrophobicContact CD2-CD2 4.22Å; F499-L521 HydrophobicContact CE1-CD2 4.12Å; F499-L521 HydrophobicContact CE2-CD2 3.67Å; F499-L521 HydrophobicContact CE2-CG 3.99Å; F499-L521 HydrophobicContact CZ-CD2 3.6Å; F499-L521 HydrophobicContact CZ-CG 4.23Å; F499-A524 HydrophobicContact CB-CB 3.39Å; F499-A524 HydrophobicContact CD2-CB 4.26Å; F499-A524 HydrophobicContact CG-CB 4.31Å; F499-V526 HydrophobicContact CB-CG2 3.64Å; F499-V526 HydrophobicContact CD1-CG2 4.25Å; F499-V526 HydrophobicContact CD2-CG2 4.37Å; F499-V526 HydrophobicContact CG-CG2 3.87Å
500R93.3Very high93.7Very high33 Ų3341.4 Ų41.413%0.12520%0.196CC..  trans-152.4160.7179.956.6-178.5-153.8-55.8-25.9109.9W480 A482 D502 L503 A524 V526W480-R500 PolarHBondContact O-NH1 3.06Å; A482-R500 VanDerWaalsContact O-CZ 3.3Å; A482-R500 PolarHBondContact O-NH1 2.61Å; A482-R500 PolarHBondContact O-NH2 2.91Å; R500-D502 VanDerWaalsContact C-N 3.31Å; R500-D502 WeakPolarHBondContact CB-OD1 3.24Å; R500-D502 WeakPolarHBondContact CD-OD1 3.3Å; R500-D502 WeakPolarHBondContact CG-OD1 3.34Å; R500-D502 IonicContact CZ-OD2 2.72Å; R500-D502 IonicContact NE-OD1 3.36Å; R500-D502 PolarHBondContact NE-OD1 2.71Å; R500-D502 IonicContact NE-OD2 3.34Å; R500-D502 PolarHBondContact NE-OD2 3.03Å; R500-D502 IonicContact NH2-OD2 3.48Å; R500-D502 PolarHBondContact NH2-OD2 3.17Å; R500-D502 VanDerWaalsContact NH2-OD2 3.08Å; R500-D502 PolarHBondContact O-N 3.4Å; R500-L503 HydrophobicContact CG-CB 3.81Å; R500-L503 WeakPolarHBondContact O-CB 3.5Å; R500-L503 PolarHBondContact O-N 3.07Å; R500-A524 CarbonylContact C-O 3.59Å; R500-V526 WeakPolarHBondContact O-CG2 3.43Å
501K90.1Very high93.7Very high141 Ų14140.6 Ų40.661%0.61319%0.193SC*.THydrogen-bonded Turntrans-69.2-27.6-167.6-170.4178.7178.2-174.40113.8A524K501-A524 WeakPolarHBondContact CA-O 3.34Å; K501-A524 PolarHBondContact N-O 3.08Å
502D85.9Confident93.4Very high92 Ų9240.9 Ų40.949%0.49220%0.195SC..THydrogen-bonded Turntrans-88.4-2.9179.363.5-61.4000113.4R500 L504R500-D502 VanDerWaalsContact C-N 3.31Å; R500-D502 WeakPolarHBondContact CB-OD1 3.24Å; R500-D502 WeakPolarHBondContact CD-OD1 3.3Å; R500-D502 WeakPolarHBondContact CG-OD1 3.34Å; R500-D502 IonicContact CZ-OD2 2.72Å; R500-D502 IonicContact NE-OD1 3.36Å; R500-D502 PolarHBondContact NE-OD1 2.71Å; R500-D502 IonicContact NE-OD2 3.34Å; R500-D502 PolarHBondContact NE-OD2 3.03Å; R500-D502 IonicContact NH2-OD2 3.48Å; R500-D502 PolarHBondContact NH2-OD2 3.17Å; R500-D502 VanDerWaalsContact NH2-OD2 3.08Å; R500-D502 PolarHBondContact O-N 3.4Å; D502-L504 PolarHBondContact O-N 3.48Å
503L93.7Very high93Very high0 Ų041 Ų410%020%0.203CC..  trans-77.2124-175.6175.158000112.1W480 A482 V485 F499 R500 L505 V526 H527W480-L503 HydrophobicContact CE3-CD2 4.08Å; W480-L503 HydrophobicContact CZ3-CD2 3.91Å; A482-L503 WeakPolarHBondContact O-CD1 3.33Å; V485-L503 HydrophobicContact CB-CD1 3.9Å; V485-L503 HydrophobicContact CG2-CD1 3.52Å; F499-L503 HydrophobicContact CD1-CD2 4.46Å; R500-L503 HydrophobicContact CG-CB 3.81Å; R500-L503 WeakPolarHBondContact O-CB 3.5Å; R500-L503 PolarHBondContact O-N 3.07Å; L503-L505 HydrophobicContact CG-CB 4.42Å; L503-V526 HydrophobicContact CB-CG1 4.34Å; L503-V526 HydrophobicContact CD2-CG1 4.24Å; L503-V526 HydrophobicContact CD2-CG2 4.45Å; L503-V526 HydrophobicContact CG-CG1 4.18Å; L503-H527 WeakPolarHBondContact O-CB 3.38Å; L503-H527 PolarHBondContact O-N 2.68Å
504L96.7Very high92.9Very high17 Ų1739.2 Ų39.29%0.08918%0.184CC..EExtended strand (participates in β ladder)trans-88.9108158.8177.561.3000110.3E483 M484 V485 D502 H527 I529 L739 L744E483-L504 WeakPolarHBondContact O-CB 3.33Å; E483-L504 PolarHBondContact O-N 3.46Å; M484-L504 WeakPolarHBondContact CA-O 3.31Å; M484-L504 HydrophobicContact CB-CD2 4.37Å; M484-L504 HydrophobicContact CG-CD2 4Å; M484-L504 HydrophobicContact CG-CG 4.2Å; M484-L504 HydrophobicContact SD-CD2 4.03Å; V485-L504 PolarHBondContact N-O 2.92Å; D502-L504 PolarHBondContact O-N 3.48Å; L504-H527 CarbonylContact C-O 3.52Å; L504-H527 VanDerWaalsContact CA-O 3.3Å; L504-H527 WeakPolarHBondContact CA-O 3.43Å; L504-H527 HydrophobicContact CD1-CB 4.39Å; L504-I529 HydrophobicContact CD1-CD1 4.02Å; L504-I529 HydrophobicContact CD1-CG1 4.19Å; L504-L739 HydrophobicContact CD2-CB 4.14Å; L504-L739 HydrophobicContact CD2-CD2 3.98Å; L504-L739 HydrophobicContact CD2-CG 4.44Å; L504-L744 HydrophobicContact CD1-CD1 4.21Å; L504-L744 HydrophobicContact CD1-CD2 4.3Å; L504-L744 HydrophobicContact CD2-CD1 4.47Å
505L98Very high93Very high0 Ų036.1 Ų36.10%017%0.168CC..EExtended strand (participates in β ladder)trans-99.7120.4174.7177.864.4000110.3W480 V485 K487 P491 L503 T507 L509 L521 V526 H527 S528 I529W480-L505 HydrophobicContact CH2-CD1 4.19Å; W480-L505 HydrophobicContact CZ3-CD1 4.22Å; V485-L505 HydrophobicContact CB-CD1 4.27Å; V485-L505 HydrophobicContact CG1-CD1 4.09Å; K487-L505 HydrophobicContact CD-CD1 4.45Å; P491-L505 HydrophobicContact CG-CD2 3.68Å; L503-L505 HydrophobicContact CG-CB 4.42Å; L505-T507 HydrophobicContact CD1-CG2 3.96Å; L505-T507 HydrophobicContact CD2-CG2 4.08Å; L505-T507 HydrophobicContact CG-CG2 3.84Å; L505-L509 HydrophobicContact CD2-CD2 4.1Å; L505-L521 HydrophobicContact CD2-CD2 4.05Å; L505-V526 HydrophobicContact CB-CG1 3.93Å; L505-H527 PolarHBondContact N-O 3.37Å; L505-S528 WeakPolarHBondContact O-CA 3.27Å; L505-I529 PolarHBondContact O-N 3.42Å
506F98.1Very high93.1Very high0 Ų039.9 Ų39.90%019%0.193CC..EExtended strand (participates in β ladder)trans-122.2102.6178.5-170.1-141.3000110.4V485 L486 K487 I529 Y531 V534 L543 V736 L739V485-F506 PolarHBondContact O-N 2.85Å; L486-F506 HydrophobicContact CD2-CB 4.09Å; L486-F506 HydrophobicContact CD2-CD1 3.94Å; K487-F506 PolarHBondContact N-O 3.39Å; F506-I529 HydrophobicContact CD2-CB 3.77Å; F506-I529 HydrophobicContact CD2-CG2 3.69Å; F506-I529 WeakPolarHBondContact CD2-O 3.39Å; F506-I529 HydrophobicContact CE2-CB 4.26Å; F506-I529 HydrophobicContact CE2-CG2 3.65Å; F506-Y531 VanDerWaalsContact C-CE1 3.42Å; F506-Y531 HydrophobicContact CB-CE1 4.28Å; F506-Y531 HydrophobicContact CD1-CD1 4.48Å; F506-Y531 AromaticContact CD1-CE1 3.62Å; F506-Y531 HydrophobicContact CD1-CE1 3.62Å; F506-Y531 AromaticContact CD2-CD1 3.63Å; F506-Y531 HydrophobicContact CD2-CD1 3.63Å; F506-Y531 AromaticContact CD2-CE1 3.43Å; F506-Y531 HydrophobicContact CD2-CE1 3.43Å; F506-Y531 VanDerWaalsContact CD2-CE1 3.43Å; F506-Y531 HydrophobicContact CE1-CD1 4.26Å; F506-Y531 AromaticContact CE1-CE1 3.67Å; F506-Y531 HydrophobicContact CE1-CE1 3.67Å; F506-Y531 AromaticContact CE2-CD1 3.38Å; F506-Y531 HydrophobicContact CE2-CD1 3.38Å; F506-Y531 AromaticContact CE2-CE1 3.5Å; F506-Y531 HydrophobicContact CE2-CE1 3.5Å; F506-Y531 HydrophobicContact CG-CD1 4.18Å; F506-Y531 AromaticContact CG-CE1 3.49Å; F506-Y531 HydrophobicContact CG-CE1 3.49Å; F506-Y531 VanDerWaalsContact CG-CE1 3.49Å; F506-Y531 AromaticContact CZ-CD1 3.72Å; F506-Y531 HydrophobicContact CZ-CD1 3.72Å; F506-Y531 AromaticContact CZ-CE1 3.61Å; F506-Y531 HydrophobicContact CZ-CE1 3.61Å; F506-Y531 WeakPolarHBondContact O-CE1 3.34Å; F506-Y531 VanDerWaalsContact O-CZ 3.3Å; F506-Y531 PolarHBondContact O-OH 2.9Å; F506-V534 HydrophobicContact CE2-CG2 4.2Å; F506-L543 HydrophobicContact CE2-CD1 4.1Å; F506-L543 HydrophobicContact CZ-CD1 3.68Å; F506-V736 HydrophobicContact CD1-CG2 4.03Å; F506-V736 HydrophobicContact CE1-CG2 3.85Å; F506-L739 HydrophobicContact CB-CD1 4.36Å; F506-L739 HydrophobicContact CD1-CD1 3.55Å; F506-L739 HydrophobicContact CD2-CD1 4.15Å; F506-L739 HydrophobicContact CE1-CD1 3.79Å; F506-L739 HydrophobicContact CE2-CD1 4.34Å; F506-L739 HydrophobicContact CG-CD1 3.77Å; F506-L739 HydrophobicContact CZ-CD1 4.19Å
507T97.8Very high93.2Very high0 Ų037.2 Ų37.20%018%0.182CC..EExtended strand (participates in β ladder)trans-160.5175.9-171.3-170.20000112K487 V488 K489 L505 L509 I529 A530 Y531K487-T507 VanDerWaalsContact C-OG1 3.22Å; K487-T507 HydrophobicContact CB-CG2 4.44Å; K487-T507 VanDerWaalsContact CB-OG1 3.26Å; K487-T507 WeakPolarHBondContact CB-OG1 3.47Å; K487-T507 PolarHBondContact O-OG1 3.44Å; V488-T507 VanDerWaalsContact C-OG1 3.23Å; V488-T507 PolarHBondContact O-OG1 3.25Å; K489-T507 PolarHBondContact N-OG1 3.42Å; K489-T507 PolarHBondContact O-OG1 2.94Å; L505-T507 HydrophobicContact CD1-CG2 3.96Å; L505-T507 HydrophobicContact CD2-CG2 4.08Å; L505-T507 HydrophobicContact CG-CG2 3.84Å; T507-L509 HydrophobicContact CG2-CD2 3.57Å; T507-L509 HydrophobicContact CG2-CG 4.17Å; T507-I529 PolarHBondContact N-O 3.18Å; T507-A530 CarbonylContact O-C 3.54Å; T507-A530 VanDerWaalsContact O-CA 3.3Å; T507-A530 WeakPolarHBondContact O-CA 3.27Å; T507-Y531 VanDerWaalsContact CA-CZ 3.5Å; T507-Y531 PolarHBondContact O-N 2.92Å
508Y95.4Very high93.4Very high5 Ų529.4 Ų29.42%0.0215%0.153CC..  trans-72.6133.8161.2-70.8-66.6000110.5V488 K489 E490 Y531 E532 L543 L544 M547 L728V488-Y508 WeakPolarHBondContact O-CB 3.29Å; V488-Y508 WeakPolarHBondContact O-CD2 3.42Å; V488-Y508 PolarHBondContact O-N 3.43Å; K489-Y508 CarbonylContact C-O 3.6Å; E490-Y508 WeakPolarHBondContact CA-O 3.48Å; E490-Y508 WeakPolarHBondContact CB-O 3.49Å; E490-Y508 PolarHBondContact N-O 3.49Å; Y508-Y531 HydrophobicContact CD1-CD2 4.19Å; Y508-Y531 HydrophobicContact CD1-CG 4.35Å; Y508-Y531 AromaticContact CD2-CD2 3.76Å; Y508-Y531 HydrophobicContact CD2-CD2 3.76Å; Y508-Y531 VanDerWaalsContact CE1-CB 3.44Å; Y508-Y531 HydrophobicContact CE1-CD2 4.22Å; Y508-Y531 HydrophobicContact CE1-CG 4.36Å; Y508-Y531 AromaticContact CE2-CD2 3.8Å; Y508-Y531 HydrophobicContact CE2-CD2 3.8Å; Y508-Y531 AromaticContact CG-CD2 3.92Å; Y508-Y531 HydrophobicContact CG-CD2 3.92Å; Y508-Y531 HydrophobicContact CG-CG 4.45Å; Y508-E532 VanDerWaalsContact CA-OE2 3.3Å; Y508-E532 WeakPolarHBondContact CA-OE2 3.5Å; Y508-E532 HydrophobicContact CD1-CB 4.03Å; Y508-E532 WeakPolarHBondContact CD1-OE2 3.38Å; Y508-E532 HydrophobicContact CE1-CB 4.24Å; Y508-L543 PolarHBondContact OH-O 3.02Å; Y508-L544 HydrophobicContact CD1-CD1 4.48Å; Y508-L544 HydrophobicContact CE1-CD1 3.72Å; Y508-M547 HydrophobicContact CE2-CG 3.77Å; Y508-M547 WeakPolarHBondContact OH-CG 3.15Å; Y508-L728 HydrophobicContact CE2-CD1 3.97Å; Y508-L728 HydrophobicContact CE2-CD2 4.37Å
509L94.3Very high93.8Very high0 Ų033.3 Ų33.30%017%0.171CC..  trans-115.3-40.2-175.6-69.4179000114.7E490 L505 T507 L511 L521 A530 E532 N759E490-L509 WeakPolarHBondContact CB-O 3.38Å; L505-L509 HydrophobicContact CD2-CD2 4.1Å; T507-L509 HydrophobicContact CG2-CD2 3.57Å; T507-L509 HydrophobicContact CG2-CG 4.17Å; L509-L511 VanDerWaalsContact C-N 3.28Å; L509-L511 HydrophobicContact CB-CD2 3.81Å; L509-L511 HydrophobicContact CB-CG 3.83Å; L509-L511 HydrophobicContact CD1-CD1 4.32Å; L509-L511 HydrophobicContact CD1-CD2 4.41Å; L509-L511 HydrophobicContact CD1-CG 4.26Å; L509-L511 PolarHBondContact O-N 2.9Å; L509-L521 HydrophobicContact CD2-CD1 4.31Å; L509-A530 HydrophobicContact CB-CB 4.09Å; L509-A530 HydrophobicContact CD1-CB 3.84Å; L509-A530 HydrophobicContact CG-CB 4.02Å; L509-E532 PolarHBondContact N-OE1 3.27Å; L509-E532 PolarHBondContact N-OE2 3.44Å; L509-N759 HydrophobicContact CD1-CB 3.85Å
510H90.4Very high93.9Very high12 Ų1233 Ų336%0.05617%0.173CC..  trans52.142.5-176.9-50.5-81.1000113.2K489 E490 A512 A513 E532 D684 Q685K489-H510 PolarHBondContact NZ-CD2 3.25Å; K489-H510 VanDerWaalsContact NZ-CD2 3.3Å; K489-H510 PolarHBondContact NZ-NE2 2.89Å; E490-H510 IonicContact OE2-CD2 3.17Å; H510-A512 VanDerWaalsContact C-N 3.27Å; H510-A512 PolarHBondContact O-N 3.33Å; H510-A513 PolarHBondContact O-N 3.47Å; H510-A513 VanDerWaalsContact O-N 3.11Å; H510-E532 WeakPolarHBondContact CA-OE1 3.44Å; H510-E532 PolarHBondContact N-OE1 3.19Å; H510-D684 IonicContact CE1-OD2 3.05Å; H510-D684 PolarHBondContact CE1-OD2 2.68Å; H510-D684 IonicContact ND1-OD2 2.65Å; H510-D684 IonicContact NE2-OD2 3.16Å; H510-Q685 PolarHBondContact ND1-NE2 2.99Å
511L94Very high94.1Very high2 Ų231.5 Ų31.51%0.0117%0.167CC..G310 helixtrans-59-34.2-170.3-65.3-166.3000113.5L509 A513 N514 L517 T518 L521 N759 T760 L765 V770 L774L509-L511 VanDerWaalsContact C-N 3.28Å; L509-L511 HydrophobicContact CB-CD2 3.81Å; L509-L511 HydrophobicContact CB-CG 3.83Å; L509-L511 HydrophobicContact CD1-CD1 4.32Å; L509-L511 HydrophobicContact CD1-CD2 4.41Å; L509-L511 HydrophobicContact CD1-CG 4.26Å; L509-L511 PolarHBondContact O-N 2.9Å; L511-A513 PolarHBondContact O-N 3.3Å; L511-N514 PolarHBondContact O-N 3.07Å; L511-L517 HydrophobicContact CD2-CD2 3.77Å; L511-L517 HydrophobicContact CD2-CG 3.89Å; L511-T518 HydrophobicContact CD1-CG2 4.4Å; L511-L521 HydrophobicContact CD1-CD1 4.36Å; L511-L521 HydrophobicContact CD2-CD1 3.88Å; L511-N759 HydrophobicContact CD1-CB 3.88Å; L511-N759 WeakPolarHBondContact CD1-OD1 3.42Å; L511-T760 HydrophobicContact CD1-CG2 4.31Å; L511-L765 HydrophobicContact CD1-CD1 4.33Å; L511-V770 HydrophobicContact CB-CG1 3.59Å; L511-V770 HydrophobicContact CB-CG2 4.17Å; L511-L774 WeakPolarHBondContact O-CD1 3.2Å
512A90Very high94.4Very high7 Ų726.3 Ų26.36%0.05815%0.146CC..G310 helixtrans-55.8-26.1179.300000113.6H510 V770 D773 L774H510-A512 VanDerWaalsContact C-N 3.27Å; H510-A512 PolarHBondContact O-N 3.33Å; A512-V770 HydrophobicContact CB-CG2 4.2Å; A512-D773 HydrophobicContact CB-CB 4.37Å; A512-L774 WeakPolarHBondContact O-CD2 3.5Å
513A85.1Confident94.9Very high53 Ų5331.1 Ų31.144%0.43816%0.162SC..G310 helixtrans-102.91177.400000113.8H510 L511H510-A513 PolarHBondContact O-N 3.47Å; H510-A513 VanDerWaalsContact O-N 3.11Å; L511-A513 PolarHBondContact O-N 3.3Å
514N90.1Very high95Very high35 Ų3532.4 Ų32.419%0.18717%0.173CC..  trans-136.569.3-168.3-163.3-15.4000113.7L511 P516 L517 T518L511-N514 PolarHBondContact O-N 3.07Å; N514-P516 VanDerWaalsContact C-CD 3.47Å; N514-P516 WeakPolarHBondContact OD1-CD 3.4Å; N514-L517 HydrophobicContact CB-CB 4.18Å; N514-L517 WeakPolarHBondContact ND2-CB 3.41Å; N514-L517 PolarHBondContact O-N 2.87Å; N514-L517 WeakPolarHBondContact OD1-CB 3.38Å; N514-L517 PolarHBondContact OD1-N 3.27Å; N514-T518 PolarHBondContact O-N 3.24Å; N514-T518 VanDerWaalsContact O-N 3.08Å; N514-T518 PolarHBondContact O-OG1 3.23Å; N514-T518 VanDerWaalsContact O-OG1 3.08Å
515K93.9Very high95Very high77 Ų7731.9 Ų31.934%0.33517%0.172SC..Hα-helixtrans-52.9-41.5177.5-162.1164-178.5159.30114.3T518 K519 L774K515-T518 PolarHBondContact O-N 3.21Å; K515-K519 WeakPolarHBondContact O-CG 3.23Å; K515-K519 PolarHBondContact O-N 3.25Å; K515-L774 HydrophobicContact CB-CD1 4.45Å; K515-L774 HydrophobicContact CB-CD2 3.94Å; K515-L774 VanDerWaalsContact CE-O 3.27Å; K515-L774 WeakPolarHBondContact CE-O 3.45Å; K515-L774 HydrophobicContact CG-CD2 4.42Å; K515-L774 PolarHBondContact NZ-O 3.35Å
516P96Very high94.9Very high84 Ų8431.9 Ų31.955%0.54517%0.172SC..Hα-helixtrans-59.8-47.9177.1-26.136.3000113.5N514 K519 A520N514-P516 VanDerWaalsContact C-CD 3.47Å; N514-P516 WeakPolarHBondContact OD1-CD 3.4Å; P516-K519 PolarHBondContact O-N 3.19Å; P516-A520 PolarHBondContact O-N 2.95Å
517L96.7Very high94.9Very high0 Ų033.1 Ų33.10%018%0.178CC..Hα-helixtrans-61-46.7176.7172.861.1000111.4E490 P491 Y496 F499 L511 N514 K519 A520 L521E490-L517 HydrophobicContact CB-CD2 3.7Å; E490-L517 HydrophobicContact CG-CD2 4.17Å; P491-L517 HydrophobicContact CB-CD1 4.09Å; P491-L517 HydrophobicContact CG-CD1 4.19Å; Y496-L517 HydrophobicContact CD1-CD1 4.37Å; Y496-L517 HydrophobicContact CE1-CB 4.5Å; Y496-L517 HydrophobicContact CE1-CD1 3.59Å; Y496-L517 WeakPolarHBondContact OH-CA 3.46Å; Y496-L517 WeakPolarHBondContact OH-CB 3.44Å; Y496-L517 PolarHBondContact OH-N 2.73Å; F499-L517 HydrophobicContact CE2-CD1 4.2Å; F499-L517 HydrophobicContact CZ-CD1 3.91Å; L511-L517 HydrophobicContact CD2-CD2 3.77Å; L511-L517 HydrophobicContact CD2-CG 3.89Å; N514-L517 HydrophobicContact CB-CB 4.18Å; N514-L517 WeakPolarHBondContact ND2-CB 3.41Å; N514-L517 PolarHBondContact O-N 2.87Å; N514-L517 WeakPolarHBondContact OD1-CB 3.38Å; N514-L517 PolarHBondContact OD1-N 3.27Å; L517-K519 VanDerWaalsContact C-N 3.28Å; L517-K519 PolarHBondContact O-N 3.41Å; L517-A520 PolarHBondContact O-N 3.37Å; L517-L521 HydrophobicContact CD1-CD1 3.99Å; L517-L521 HydrophobicContact CD1-CG 3.96Å; L517-L521 HydrophobicContact CG-CD1 3.98Å; L517-L521 HydrophobicContact CG-CG 4.4Å; L517-L521 WeakPolarHBondContact O-CG 3.38Å; L517-L521 PolarHBondContact O-N 3.43Å
518T97.3Very high94.9Very high0 Ų033.1 Ų33.10%018%0.178CC..Hα-helixtrans-55.4-46.4178.4-54.30000110.9L511 N514 K515 A520 L521 L522 L765 L774 L776L511-T518 HydrophobicContact CD1-CG2 4.4Å; N514-T518 PolarHBondContact O-N 3.24Å; N514-T518 VanDerWaalsContact O-N 3.08Å; N514-T518 PolarHBondContact O-OG1 3.23Å; N514-T518 VanDerWaalsContact O-OG1 3.08Å; K515-T518 PolarHBondContact O-N 3.21Å; T518-A520 PolarHBondContact O-N 3.18Å; T518-L521 PolarHBondContact O-N 3.19Å; T518-L522 HydrophobicContact CG2-CD1 4.01Å; T518-L522 HydrophobicContact CG2-CG 4.48Å; T518-L522 WeakPolarHBondContact O-CG 3.44Å; T518-L522 PolarHBondContact O-N 2.89Å; T518-L765 HydrophobicContact CG2-CD1 4.17Å; T518-L765 HydrophobicContact CG2-CD2 4.36Å; T518-L774 HydrophobicContact CG2-CD1 3.88Å; T518-L774 VanDerWaalsContact OG1-CD1 3.3Å; T518-L774 WeakPolarHBondContact OG1-CD1 3.45Å; T518-L776 HydrophobicContact CG2-CD1 3.65Å
519K97.3Very high95Very high119 Ų11932.9 Ų32.952%0.51718%0.177SC..Hα-helixtrans-63.3-39.2177-75.3-176.2172.8-173.50112.8K515 P516 L517 K523K515-K519 WeakPolarHBondContact O-CG 3.23Å; K515-K519 PolarHBondContact O-N 3.25Å; P516-K519 PolarHBondContact O-N 3.19Å; L517-K519 VanDerWaalsContact C-N 3.28Å; L517-K519 PolarHBondContact O-N 3.41Å; K519-K523 VanDerWaalsContact O-CB 3.26Å; K519-K523 WeakPolarHBondContact O-CB 3.29Å; K519-K523 PolarHBondContact O-N 2.84Å
520A97.2Very high95.1Very high17 Ų1732.9 Ų32.914%0.1418%0.177CC..Hα-helixtrans-65.4-45.117900000111.9Y496 F499 P516 L517 T518 K523 A524Y496-A520 HydrophobicContact CD1-CB 4.22Å; Y496-A520 HydrophobicContact CD2-CB 3.53Å; Y496-A520 HydrophobicContact CE1-CB 4.46Å; Y496-A520 HydrophobicContact CE2-CB 3.79Å; Y496-A520 HydrophobicContact CG-CB 3.79Å; F499-A520 HydrophobicContact CD2-CB 4.16Å; F499-A520 HydrophobicContact CE2-CB 3.82Å; P516-A520 PolarHBondContact O-N 2.95Å; L517-A520 PolarHBondContact O-N 3.37Å; T518-A520 PolarHBondContact O-N 3.18Å; A520-K523 PolarHBondContact O-N 3.19Å; A520-A524 WeakPolarHBondContact O-CB 3.33Å; A520-A524 PolarHBondContact O-N 3.5Å
521L97.9Very high95.4Very high0 Ų032.4 Ų32.40%017%0.174CC..Hα-helixtrans-60.6-46.6175.8-70169.7000111.7F499 L505 L509 L511 L517 T518 A524 G525 V526 T760F499-L521 HydrophobicContact CD2-CD2 4.22Å; F499-L521 HydrophobicContact CE1-CD2 4.12Å; F499-L521 HydrophobicContact CE2-CD2 3.67Å; F499-L521 HydrophobicContact CE2-CG 3.99Å; F499-L521 HydrophobicContact CZ-CD2 3.6Å; F499-L521 HydrophobicContact CZ-CG 4.23Å; L505-L521 HydrophobicContact CD2-CD2 4.05Å; L509-L521 HydrophobicContact CD2-CD1 4.31Å; L511-L521 HydrophobicContact CD1-CD1 4.36Å; L511-L521 HydrophobicContact CD2-CD1 3.88Å; L517-L521 HydrophobicContact CD1-CD1 3.99Å; L517-L521 HydrophobicContact CD1-CG 3.96Å; L517-L521 HydrophobicContact CG-CD1 3.98Å; L517-L521 HydrophobicContact CG-CG 4.4Å; L517-L521 WeakPolarHBondContact O-CG 3.38Å; L517-L521 PolarHBondContact O-N 3.43Å; T518-L521 PolarHBondContact O-N 3.19Å; L521-A524 PolarHBondContact O-N 2.9Å; L521-G525 PolarHBondContact O-N 3.3Å; L521-V526 HydrophobicContact CD2-CB 3.91Å; L521-V526 HydrophobicContact CD2-CG1 3.87Å; L521-V526 HydrophobicContact CD2-CG2 4.23Å; L521-V526 PolarHBondContact O-N 3.04Å; L521-T760 HydrophobicContact CB-CG2 3.99Å; L521-T760 HydrophobicContact CD1-CG2 4.4Å
522L97Very high95.4Very high33 Ų3332.6 Ų32.617%0.17318%0.175CC..Hα-helixtrans-63.5-44.6178.5-65.4172.3000111.7T518 A524 G525 T760 G763 L765 L776T518-L522 HydrophobicContact CG2-CD1 4.01Å; T518-L522 HydrophobicContact CG2-CG 4.48Å; T518-L522 WeakPolarHBondContact O-CG 3.44Å; T518-L522 PolarHBondContact O-N 2.89Å; L522-A524 VanDerWaalsContact C-N 3.34Å; L522-A524 PolarHBondContact O-N 3.13Å; L522-G525 PolarHBondContact O-N 3.15Å; L522-T760 HydrophobicContact CD2-CG2 3.88Å; L522-T760 HydrophobicContact CG-CG2 4.4Å; L522-G763 WeakPolarHBondContact CD2-O 3.41Å; L522-G763 WeakPolarHBondContact O-CA 3.41Å; L522-L765 HydrophobicContact CD1-CB 4.4Å; L522-L765 HydrophobicContact CD2-CB 4.01Å; L522-L776 HydrophobicContact CD1-CD1 4.45Å
523K96.6Very high95.6Very high192 Ų19233.1 Ų33.184%0.83518%0.177SC*.Hα-helixtrans-61.3-42.4179.1-177.3-175.8176.4-169.40112K519 A520 G525K519-K523 VanDerWaalsContact O-CB 3.26Å; K519-K523 WeakPolarHBondContact O-CB 3.29Å; K519-K523 PolarHBondContact O-N 2.84Å; A520-K523 PolarHBondContact O-N 3.19Å; K523-G525 VanDerWaalsContact C-N 3.29Å
524A96Very high96.1Very high27 Ų2730.6 Ų30.622%0.22316%0.156CC..Hα-helixtrans-79.9-11.9-178.800000113.5F499 R500 K501 A520 L521 L522 V526F499-A524 HydrophobicContact CB-CB 3.39Å; F499-A524 HydrophobicContact CD2-CB 4.26Å; F499-A524 HydrophobicContact CG-CB 4.31Å; R500-A524 CarbonylContact C-O 3.59Å; K501-A524 WeakPolarHBondContact CA-O 3.34Å; K501-A524 PolarHBondContact N-O 3.08Å; A520-A524 WeakPolarHBondContact O-CB 3.33Å; A520-A524 PolarHBondContact O-N 3.5Å; L521-A524 PolarHBondContact O-N 2.9Å; L522-A524 VanDerWaalsContact C-N 3.34Å; L522-A524 PolarHBondContact O-N 3.13Å; A524-V526 VanDerWaalsContact C-N 3.31Å; A524-V526 HydrophobicContact CB-CG2 3.94Å
525G95.8Very high96.3Very high7 Ų731 Ų317%0.07216%0.157CC..THydrogen-bonded Turntrans75.317.718000000114.4L521 L522 K523 H527L521-G525 PolarHBondContact O-N 3.3Å; L522-G525 PolarHBondContact O-N 3.15Å; K523-G525 VanDerWaalsContact C-N 3.29Å; G525-H527 PolarHBondContact O-CD2 2.87Å
526V96.8Very high96.3Very high0 Ų028.8 Ų28.80%015%0.151CC..  trans-61140.4-176.5176.30000111.3F499 R500 L503 L505 L521 A524 T760F499-V526 HydrophobicContact CB-CG2 3.64Å; F499-V526 HydrophobicContact CD1-CG2 4.25Å; F499-V526 HydrophobicContact CD2-CG2 4.37Å; F499-V526 HydrophobicContact CG-CG2 3.87Å; R500-V526 WeakPolarHBondContact O-CG2 3.43Å; L503-V526 HydrophobicContact CB-CG1 4.34Å; L503-V526 HydrophobicContact CD2-CG1 4.24Å; L503-V526 HydrophobicContact CD2-CG2 4.45Å; L503-V526 HydrophobicContact CG-CG1 4.18Å; L505-V526 HydrophobicContact CB-CG1 3.93Å; L521-V526 HydrophobicContact CD2-CB 3.91Å; L521-V526 HydrophobicContact CD2-CG1 3.87Å; L521-V526 HydrophobicContact CD2-CG2 4.23Å; L521-V526 PolarHBondContact O-N 3.04Å; A524-V526 VanDerWaalsContact C-N 3.31Å; A524-V526 HydrophobicContact CB-CG2 3.94Å; V526-T760 CarbonylContact O-C 3.04Å; V526-T760 PolarHBondContact O-OG1 2.96Å
527H96.8Very high96.2Very high26 Ų2628.6 Ų28.612%0.1216%0.156CC..EExtended strand (participates in β ladder)trans-88.1105.9169.3-57.7173.3000107.7L503 L504 L505 G525 L744 T760 Y761 N762L503-H527 WeakPolarHBondContact O-CB 3.38Å; L503-H527 PolarHBondContact O-N 2.68Å; L504-H527 CarbonylContact C-O 3.52Å; L504-H527 VanDerWaalsContact CA-O 3.3Å; L504-H527 WeakPolarHBondContact CA-O 3.43Å; L504-H527 HydrophobicContact CD1-CB 4.39Å; L505-H527 PolarHBondContact N-O 3.37Å; G525-H527 PolarHBondContact O-CD2 2.87Å; H527-L744 HydrophobicContact CB-CD2 4.05Å; H527-L744 WeakPolarHBondContact ND1-CD2 3.43Å; H527-T760 CarbonylContact C-O 3.43Å; H527-T760 WeakPolarHBondContact CA-O 3.38Å; H527-Y761 HydrophobicContact CB-CD2 4.48Å; H527-Y761 AromaticContact CD2-CD2 3.81Å; H527-Y761 AromaticContact CE1-CE2 3.73Å; H527-Y761 AromaticContact CG-CD2 3.85Å; H527-Y761 AromaticContact ND1-CE2 3.83Å; H527-Y761 AromaticContact NE2-CE2 3.9Å; H527-N762 PolarHBondContact NE2-OD1 3.38Å
528S98Very high95.9Very high0 Ų034 Ų340%019%0.185CC..EExtended strand (participates in β ladder)trans-116.4130.5-176.570.90000111.7L505 N759 T760L505-S528 WeakPolarHBondContact O-CA 3.27Å; S528-N759 PolarHBondContact O-N 2.82Å; S528-T760 WeakPolarHBondContact CB-OG1 3.35Å; S528-T760 PolarHBondContact N-O 3.1Å; S528-T760 PolarHBondContact N-OG1 2.83Å; S528-T760 PolarHBondContact O-N 3.42Å; S528-T760 WeakPolarHBondContact OG-CB 3.47Å; S528-T760 PolarHBondContact OG-N 3.46Å; S528-T760 PolarHBondContact OG-OG1 3.49Å
529I97.9Very high95.5Very high0 Ų038.5 Ų38.50%021%0.209CC..EExtended strand (participates in β ladder)trans-115.4123.1173.2-59.8179.6000107.4L504 L505 F506 T507 V534 L739 L744 L748 L754 G757 L758L504-I529 HydrophobicContact CD1-CD1 4.02Å; L504-I529 HydrophobicContact CD1-CG1 4.19Å; L505-I529 PolarHBondContact O-N 3.42Å; F506-I529 HydrophobicContact CD2-CB 3.77Å; F506-I529 HydrophobicContact CD2-CG2 3.69Å; F506-I529 WeakPolarHBondContact CD2-O 3.39Å; F506-I529 HydrophobicContact CE2-CB 4.26Å; F506-I529 HydrophobicContact CE2-CG2 3.65Å; T507-I529 PolarHBondContact N-O 3.18Å; I529-V534 HydrophobicContact CG2-CG2 4.05Å; I529-L739 HydrophobicContact CD1-CD1 4.37Å; I529-L739 HydrophobicContact CD1-CD2 3.63Å; I529-L744 HydrophobicContact CD1-CD1 4.28Å; I529-L748 HydrophobicContact CD1-CD2 4.31Å; I529-L754 HydrophobicContact CD1-CD2 4.4Å; I529-L754 HydrophobicContact CG2-CD2 4.24Å; I529-G757 WeakPolarHBondContact CA-O 3.46Å; I529-L758 HydrophobicContact CG1-CD1 4.02Å
530A97Very high95.2Very high0 Ų035 Ų350%020%0.199CC..EExtended strand (participates in β ladder)trans-93.2127.7-177.500000111.2T507 L509 E532 N533 V534 G757 N759T507-A530 CarbonylContact O-C 3.54Å; T507-A530 VanDerWaalsContact O-CA 3.3Å; T507-A530 WeakPolarHBondContact O-CA 3.27Å; L509-A530 HydrophobicContact CB-CB 4.09Å; L509-A530 HydrophobicContact CD1-CB 3.84Å; L509-A530 HydrophobicContact CG-CB 4.02Å; A530-E532 VanDerWaalsContact C-N 3.25Å; A530-E532 WeakPolarHBondContact CB-OE2 3.19Å; A530-E532 PolarHBondContact O-N 3.25Å; A530-N533 HydrophobicContact CB-CB 4.26Å; A530-N533 WeakPolarHBondContact CB-OD1 3.36Å; A530-N533 PolarHBondContact O-N 3.12Å; A530-N533 VanDerWaalsContact O-N 3.08Å; A530-V534 PolarHBondContact O-N 3.23Å; A530-G757 PolarHBondContact N-O 3.35Å; A530-N759 WeakPolarHBondContact CB-ND2 3.43Å
531Y96.8Very high95Very high1 Ų135.6 Ų35.60%0.00420%0.2CC..G310 helixtrans-53-45177-67.7-13.1000111.9K487 F506 T507 Y508 N533 V534 L543 L728 T732K487-Y531 WeakPolarHBondContact O-CE2 3.49Å; K487-Y531 PolarHBondContact O-OH 3.12Å; F506-Y531 VanDerWaalsContact C-CE1 3.42Å; F506-Y531 HydrophobicContact CB-CE1 4.28Å; F506-Y531 HydrophobicContact CD1-CD1 4.48Å; F506-Y531 AromaticContact CD1-CE1 3.62Å; F506-Y531 HydrophobicContact CD1-CE1 3.62Å; F506-Y531 AromaticContact CD2-CD1 3.63Å; F506-Y531 HydrophobicContact CD2-CD1 3.63Å; F506-Y531 AromaticContact CD2-CE1 3.43Å; F506-Y531 HydrophobicContact CD2-CE1 3.43Å; F506-Y531 VanDerWaalsContact CD2-CE1 3.43Å; F506-Y531 HydrophobicContact CE1-CD1 4.26Å; F506-Y531 AromaticContact CE1-CE1 3.67Å; F506-Y531 HydrophobicContact CE1-CE1 3.67Å; F506-Y531 AromaticContact CE2-CD1 3.38Å; F506-Y531 HydrophobicContact CE2-CD1 3.38Å; F506-Y531 AromaticContact CE2-CE1 3.5Å; F506-Y531 HydrophobicContact CE2-CE1 3.5Å; F506-Y531 HydrophobicContact CG-CD1 4.18Å; F506-Y531 AromaticContact CG-CE1 3.49Å; F506-Y531 HydrophobicContact CG-CE1 3.49Å; F506-Y531 VanDerWaalsContact CG-CE1 3.49Å; F506-Y531 AromaticContact CZ-CD1 3.72Å; F506-Y531 HydrophobicContact CZ-CD1 3.72Å; F506-Y531 AromaticContact CZ-CE1 3.61Å; F506-Y531 HydrophobicContact CZ-CE1 3.61Å; F506-Y531 WeakPolarHBondContact O-CE1 3.34Å; F506-Y531 VanDerWaalsContact O-CZ 3.3Å; F506-Y531 PolarHBondContact O-OH 2.9Å; T507-Y531 VanDerWaalsContact CA-CZ 3.5Å; T507-Y531 PolarHBondContact O-N 2.92Å; Y508-Y531 HydrophobicContact CD1-CD2 4.19Å; Y508-Y531 HydrophobicContact CD1-CG 4.35Å; Y508-Y531 AromaticContact CD2-CD2 3.76Å; Y508-Y531 HydrophobicContact CD2-CD2 3.76Å; Y508-Y531 VanDerWaalsContact CE1-CB 3.44Å; Y508-Y531 HydrophobicContact CE1-CD2 4.22Å; Y508-Y531 HydrophobicContact CE1-CG 4.36Å; Y508-Y531 AromaticContact CE2-CD2 3.8Å; Y508-Y531 HydrophobicContact CE2-CD2 3.8Å; Y508-Y531 AromaticContact CG-CD2 3.92Å; Y508-Y531 HydrophobicContact CG-CD2 3.92Å; Y508-Y531 HydrophobicContact CG-CG 4.45Å; Y531-N533 PolarHBondContact O-N 2.7Å; Y531-V534 PolarHBondContact O-N 3.42Å; Y531-L543 HydrophobicContact CD1-CD1 4.05Å; Y531-L543 HydrophobicContact CG-CD1 4.45Å; Y531-L543 WeakPolarHBondContact O-CB 2.95Å; Y531-L728 HydrophobicContact CD2-CD1 4.18Å; Y531-L728 HydrophobicContact CE2-CD1 4.32Å; Y531-L728 HydrophobicContact CE2-CD2 4.29Å; Y531-T732 HydrophobicContact CD1-CG2 4.44Å; Y531-T732 HydrophobicContact CE1-CG2 4.16Å; Y531-T732 HydrophobicContact CE2-CG2 4.25Å
532E93.1Very high94.9Very high7 Ų737.3 Ų37.33%0.03321%0.211CC..G310 helixtrans-69.4-9.2-177.972.3-81.6-161.500115Y508 L509 H510 A530 L544Y508-E532 VanDerWaalsContact CA-OE2 3.3Å; Y508-E532 WeakPolarHBondContact CA-OE2 3.5Å; Y508-E532 HydrophobicContact CD1-CB 4.03Å; Y508-E532 WeakPolarHBondContact CD1-OE2 3.38Å; Y508-E532 HydrophobicContact CE1-CB 4.24Å; L509-E532 PolarHBondContact N-OE1 3.27Å; L509-E532 PolarHBondContact N-OE2 3.44Å; H510-E532 WeakPolarHBondContact CA-OE1 3.44Å; H510-E532 PolarHBondContact N-OE1 3.19Å; A530-E532 VanDerWaalsContact C-N 3.25Å; A530-E532 WeakPolarHBondContact CB-OE2 3.19Å; A530-E532 PolarHBondContact O-N 3.25Å; E532-L544 HydrophobicContact CB-CD1 4.19Å; E532-L544 HydrophobicContact CB-CD2 4.21Å
533N94.4Very high94.8Very high18 Ų1835.7 Ų35.710%0.09620%0.203CC..G310 helixtrans-110.9-8.2177.5-61.8128.2000113.7A530 Y531 Q535 R756 G757 N759A530-N533 HydrophobicContact CB-CB 4.26Å; A530-N533 WeakPolarHBondContact CB-OD1 3.36Å; A530-N533 PolarHBondContact O-N 3.12Å; A530-N533 VanDerWaalsContact O-N 3.08Å; Y531-N533 PolarHBondContact O-N 2.7Å; N533-Q535 PolarHBondContact O-N 3.03Å; N533-Q535 VanDerWaalsContact O-N 3.09Å; N533-R756 CarbonylContact O-C 3.59Å; N533-G757 PolarHBondContact O-N 2.87Å; N533-N759 PolarHBondContact OD1-ND2 2.87Å
534V95.9Very high94.7Very high0 Ų027.4 Ų27.40%017%0.167CC..  trans-63.5114.8172.21750000108.6F506 I529 A530 Y531 P542 L543 Y735 A753 L754F506-V534 HydrophobicContact CE2-CG2 4.2Å; I529-V534 HydrophobicContact CG2-CG2 4.05Å; A530-V534 PolarHBondContact O-N 3.23Å; Y531-V534 PolarHBondContact O-N 3.42Å; V534-P542 WeakPolarHBondContact O-CD 3.32Å; V534-L543 HydrophobicContact CB-CD1 3.71Å; V534-L543 HydrophobicContact CB-CG 4.12Å; V534-L543 HydrophobicContact CG1-CD1 3.99Å; V534-L543 HydrophobicContact CG1-CG 4.23Å; V534-L543 HydrophobicContact CG2-CD1 3.64Å; V534-Y735 HydrophobicContact CG1-CD1 3.95Å; V534-Y735 HydrophobicContact CG1-CE1 3.43Å; V534-Y735 VanDerWaalsContact CG1-CE1 3.43Å; V534-Y735 HydrophobicContact CG1-CE2 4.29Å; V534-A753 HydrophobicContact CG1-CB 4.04Å; V534-L754 HydrophobicContact CG2-CD2 4.42Å
535Q95Very high94.6Very high42 Ų4227.5 Ų27.520%0.19617%0.168CC..  trans-142.4111.2-168.4-176.6177.25700111.9N533 N539 S540 L541 A753 R756N533-Q535 PolarHBondContact O-N 3.03Å; N533-Q535 VanDerWaalsContact O-N 3.09Å; Q535-N539 HydrophobicContact CG-CB 4.47Å; Q535-N539 PolarHBondContact NE2-O 2.83Å; Q535-S540 WeakPolarHBondContact CA-O 3.32Å; Q535-S540 WeakPolarHBondContact CG-O 3.33Å; Q535-L541 HydrophobicContact CB-CD2 4Å; Q535-L541 HydrophobicContact CG-CD2 4.21Å; Q535-A753 PolarHBondContact N-O 3.22Å; Q535-A753 WeakPolarHBondContact O-CA 3.34Å; Q535-R756 HydrophobicContact CB-CB 4.34Å; Q535-R756 WeakPolarHBondContact O-CD 3.49Å
536P93.7Very high94.5Very high32 Ų3227.9 Ų27.921%0.20817%0.169CC..  trans-69.2-179.9176.8-9.925.4000112.7D538 N539 S540 P542 R756P536-D538 WeakPolarHBondContact CB-OD1 3.37Å; P536-D538 PolarHBondContact O-N 3.19Å; P536-N539 PolarHBondContact O-N 2.64Å; P536-S540 WeakPolarHBondContact CD-O 3.34Å; P536-P542 HydrophobicContact CG-CG 4.12Å; P536-R756 PolarHBondContact O-NH1 3.41Å
537A92.7Very high94.4Very high79 Ų7928.3 Ų28.365%0.65317%0.171SC*.THydrogen-bonded Turntrans-61.6-23.817900000114N539 L752A537-N539 PolarHBondContact O-N 3Å; A537-L752 HydrophobicContact CB-CD2 4.21Å
538D91.5Very high94.4Very high114 Ų11427.8 Ų27.861%0.6117%0.171SC*.THydrogen-bonded Turntrans-78.4-1.7175.672-10.8000113.5P536 S540P536-D538 WeakPolarHBondContact CB-OD1 3.37Å; P536-D538 PolarHBondContact O-N 3.19Å; D538-S540 VanDerWaalsContact CG-OG 3.3Å; D538-S540 PolarHBondContact O-N 3.46Å; D538-S540 VanDerWaalsContact OD1-CB 3.29Å; D538-S540 WeakPolarHBondContact OD1-CB 3.43Å; D538-S540 PolarHBondContact OD1-N 3.2Å; D538-S540 PolarHBondContact OD1-OG 3.16Å; D538-S540 PolarHBondContact OD2-OG 3.3Å
539N87.8Confident94.3Very high95 Ų9531.6 Ų31.651%0.50819%0.188SC..  trans64.314.2-177.2-53.5-54000115.3Q535 P536 A537 R756Q535-N539 HydrophobicContact CG-CB 4.47Å; Q535-N539 PolarHBondContact NE2-O 2.83Å; P536-N539 PolarHBondContact O-N 2.64Å; A537-N539 PolarHBondContact O-N 3Å; N539-R756 PolarHBondContact OD1-NH1 3.01Å; N539-R756 VanDerWaalsContact OD1-NH1 3.14Å
540S91.2Very high94.3Very high45 Ų4532.4 Ų32.432%0.31519%0.193SC..  trans-67.7159.5171.367.50000111.9Q535 P536 D538 P542Q535-S540 WeakPolarHBondContact CA-O 3.32Å; Q535-S540 WeakPolarHBondContact CG-O 3.33Å; P536-S540 WeakPolarHBondContact CD-O 3.34Å; D538-S540 VanDerWaalsContact CG-OG 3.3Å; D538-S540 PolarHBondContact O-N 3.46Å; D538-S540 VanDerWaalsContact OD1-CB 3.29Å; D538-S540 WeakPolarHBondContact OD1-CB 3.43Å; D538-S540 PolarHBondContact OD1-N 3.2Å; D538-S540 PolarHBondContact OD1-OG 3.16Å; D538-S540 PolarHBondContact OD2-OG 3.3Å; S540-P542 VanDerWaalsContact C-CD 3.48Å; S540-P542 VanDerWaalsContact O-CD 3.29Å; S540-P542 WeakPolarHBondContact O-CD 3.06Å
541L93.7Very high94.2Very high30 Ų3032.8 Ų32.816%0.15720%0.196CC..  trans-115.675.6174.4-63.4177000109.2Q535 L543 L544 A545 L654 P656Q535-L541 HydrophobicContact CB-CD2 4Å; Q535-L541 HydrophobicContact CG-CD2 4.21Å; L541-L543 VanDerWaalsContact C-N 3.26Å; L541-L543 PolarHBondContact O-N 2.84Å; L541-L544 HydrophobicContact CB-CB 3.94Å; L541-L544 HydrophobicContact CD1-CD2 3.83Å; L541-L544 PolarHBondContact O-N 2.91Å; L541-L544 VanDerWaalsContact O-N 3.12Å; L541-A545 WeakPolarHBondContact O-CB 3.48Å; L541-A545 PolarHBondContact O-N 3.45Å; L541-L654 HydrophobicContact CD1-CD2 4.46Å; L541-P656 HydrophobicContact CD1-CB 4.25Å; L541-P656 HydrophobicContact CD1-CG 4.03Å
542P94.9Very high94.2Very high35 Ų3532.8 Ų32.823%0.22720%0.196CC..THydrogen-bonded Turntrans-61.2-33.3-16823.2-34.9000113.1V534 P536 S540 P546 Y735V534-P542 WeakPolarHBondContact O-CD 3.32Å; P536-P542 HydrophobicContact CG-CG 4.12Å; S540-P542 VanDerWaalsContact C-CD 3.48Å; S540-P542 VanDerWaalsContact O-CD 3.29Å; S540-P542 WeakPolarHBondContact O-CD 3.06Å; P542-P546 WeakPolarHBondContact O-CD 3.36Å; P542-Y735 HydrophobicContact CG-CE2 4.46Å; P542-Y735 WeakPolarHBondContact CG-OH 3.42Å
543L96.1Very high94.5Very high0 Ų037.4 Ų37.40%021%0.213CC..THydrogen-bonded Turntrans-82.2-24.7-179.5-53.6-171.7000112.6F506 Y508 Y531 V534 L541 A731 T732 Y735F506-L543 HydrophobicContact CE2-CD1 4.1Å; F506-L543 HydrophobicContact CZ-CD1 3.68Å; Y508-L543 PolarHBondContact OH-O 3.02Å; Y531-L543 HydrophobicContact CD1-CD1 4.05Å; Y531-L543 HydrophobicContact CG-CD1 4.45Å; Y531-L543 WeakPolarHBondContact O-CB 2.95Å; V534-L543 HydrophobicContact CB-CD1 3.71Å; V534-L543 HydrophobicContact CB-CG 4.12Å; V534-L543 HydrophobicContact CG1-CD1 3.99Å; V534-L543 HydrophobicContact CG1-CG 4.23Å; V534-L543 HydrophobicContact CG2-CD1 3.64Å; L541-L543 VanDerWaalsContact C-N 3.26Å; L541-L543 PolarHBondContact O-N 2.84Å; L543-A731 VanDerWaalsContact CD2-C 3.41Å; L543-A731 HydrophobicContact CD2-CB 3.97Å; L543-A731 WeakPolarHBondContact CD2-O 3.5Å; L543-T732 HydrophobicContact CD1-CG2 4.44Å; L543-T732 HydrophobicContact CD2-CG2 4.01Å; L543-Y735 HydrophobicContact CD1-CD2 4.13Å; L543-Y735 HydrophobicContact CD1-CE2 4.47Å; L543-Y735 HydrophobicContact CD1-CG 4.43Å; L543-Y735 HydrophobicContact CD2-CD2 3.61Å; L543-Y735 HydrophobicContact CD2-CE2 3.66Å; L543-Y735 HydrophobicContact CG-CD2 4.23Å; L543-Y735 HydrophobicContact CG-CE2 4.18Å
544L93.6Very high94.6Very high18 Ų1837.2 Ų37.29%0.09421%0.211CC..THydrogen-bonded Turntrans-85.6-29.1175.4-172.861.5000112.6Y508 E532 L541 M547 S548 L654Y508-L544 HydrophobicContact CD1-CD1 4.48Å; Y508-L544 HydrophobicContact CE1-CD1 3.72Å; E532-L544 HydrophobicContact CB-CD1 4.19Å; E532-L544 HydrophobicContact CB-CD2 4.21Å; L541-L544 HydrophobicContact CB-CB 3.94Å; L541-L544 HydrophobicContact CD1-CD2 3.83Å; L541-L544 PolarHBondContact O-N 2.91Å; L541-L544 VanDerWaalsContact O-N 3.12Å; L544-M547 PolarHBondContact O-N 3.46Å; L544-S548 WeakPolarHBondContact O-CB 3.24Å; L544-S548 PolarHBondContact O-N 3.28Å; L544-S548 PolarHBondContact O-OG 2.94Å; L544-L654 HydrophobicContact CD2-CD2 3.4Å
545A93.4Very high94.7Very high28 Ų2837.2 Ų37.223%0.23121%0.211CC..Hα-helixtrans-50.1-53.8-178.500000113.7L541 M547 S548 E549L541-A545 WeakPolarHBondContact O-CB 3.48Å; L541-A545 PolarHBondContact O-N 3.45Å; A545-M547 VanDerWaalsContact C-N 3.3Å; A545-M547 PolarHBondContact O-N 3.42Å; A545-S548 CarbonylContact O-C 3.54Å; A545-S548 WeakPolarHBondContact O-CA 3.26Å; A545-S548 WeakPolarHBondContact O-CB 3.14Å; A545-S548 PolarHBondContact O-N 2.74Å; A545-S548 VanDerWaalsContact O-N 3.07Å; A545-E549 WeakPolarHBondContact O-CG 3.46Å; A545-E549 PolarHBondContact O-N 2.69Å
546P94.7Very high94.9Very high15 Ų1535.2 Ų35.210%0.09720%0.202CC..Hα-helixtrans-61.4-38-177.723.4-34.5000112.6P542 E549 I550 A727 A731P542-P546 WeakPolarHBondContact O-CD 3.36Å; P546-E549 PolarHBondContact O-N 3.32Å; P546-I550 WeakPolarHBondContact O-CG1 3.45Å; P546-I550 PolarHBondContact O-N 3.28Å; P546-I550 VanDerWaalsContact O-N 3.1Å; P546-A727 HydrophobicContact CB-CB 3.98Å; P546-A731 HydrophobicContact CG-CB 3.91Å
547M95.3Very high95.1Very high10 Ų1038.9 Ų38.95%0.04922%0.216CC..Hα-helixtrans-70.4-36.2176.9-64.6-54.295.300111.7R430 Y508 L544 A545 I550 A551 P717 A724 A727 L728R430-M547 PolarHBondContact NH1-SD 2.92Å; Y508-M547 HydrophobicContact CE2-CG 3.77Å; Y508-M547 WeakPolarHBondContact OH-CG 3.15Å; L544-M547 PolarHBondContact O-N 3.46Å; A545-M547 VanDerWaalsContact C-N 3.3Å; A545-M547 PolarHBondContact O-N 3.42Å; M547-I550 HydrophobicContact CE-CD1 3.84Å; M547-I550 PolarHBondContact O-N 3.07Å; M547-A551 VanDerWaalsContact O-CB 3.23Å; M547-A551 WeakPolarHBondContact O-CB 3.2Å; M547-A551 PolarHBondContact O-N 2.9Å; M547-P717 HydrophobicContact CB-CG 4.4Å; M547-P717 HydrophobicContact SD-CB 3.88Å; M547-P717 HydrophobicContact SD-CG 4.17Å; M547-A724 HydrophobicContact CE-CB 4.21Å; M547-A724 WeakPolarHBondContact CE-O 3.46Å; M547-A724 HydrophobicContact SD-CB 4.3Å; M547-A727 HydrophobicContact CE-CB 4.16Å; M547-L728 HydrophobicContact CE-CB 3.78Å; M547-L728 HydrophobicContact CG-CD1 4.39Å; M547-L728 HydrophobicContact SD-CB 4.41Å
548S94.9Very high95.3Very high15 Ų1536.3 Ų36.311%0.10519%0.191CC..Hα-helixtrans-65.1-40174.1-64.80000112.4L544 A545 G552 V593L544-S548 WeakPolarHBondContact O-CB 3.24Å; L544-S548 PolarHBondContact O-N 3.28Å; L544-S548 PolarHBondContact O-OG 2.94Å; A545-S548 CarbonylContact O-C 3.54Å; A545-S548 WeakPolarHBondContact O-CA 3.26Å; A545-S548 WeakPolarHBondContact O-CB 3.14Å; A545-S548 PolarHBondContact O-N 2.74Å; A545-S548 VanDerWaalsContact O-N 3.07Å; S548-G552 PolarHBondContact O-N 3.07Å; S548-V593 WeakPolarHBondContact O-CA 3.4Å
549E96.9Very high95.5Very high79 Ų7930.9 Ų30.937%0.36916%0.162SC..Hα-helixtrans-61.8-49.7175.1-68.5-176.815800110.8A545 P546 G552 R553 V592A545-E549 WeakPolarHBondContact O-CG 3.46Å; A545-E549 PolarHBondContact O-N 2.69Å; P546-E549 PolarHBondContact O-N 3.32Å; E549-G552 PolarHBondContact O-N 2.91Å; E549-R553 VanDerWaalsContact O-CG 3.29Å; E549-R553 WeakPolarHBondContact O-CG 3.42Å; E549-R553 PolarHBondContact O-N 3.11Å; E549-V592 HydrophobicContact CB-CG1 4.42Å; E549-V592 HydrophobicContact CG-CG1 3.49Å; E549-V592 VanDerWaalsContact CG-CG1 3.49Å
550I96.9Very high96Very high18 Ų1827.6 Ų27.69%0.09215%0.148CC..Hα-helixtrans-61.5-50.2178.4-68.5173.7000110.5P546 M547 G552 R553 M554 P717 V720 T723 A724 A727P546-I550 WeakPolarHBondContact O-CG1 3.45Å; P546-I550 PolarHBondContact O-N 3.28Å; P546-I550 VanDerWaalsContact O-N 3.1Å; M547-I550 HydrophobicContact CE-CD1 3.84Å; M547-I550 PolarHBondContact O-N 3.07Å; I550-G552 VanDerWaalsContact C-N 3.33Å; I550-G552 PolarHBondContact O-N 2.92Å; I550-R553 PolarHBondContact O-N 3.36Å; I550-M554 HydrophobicContact CG2-CG 4.16Å; I550-M554 HydrophobicContact CG2-SD 3.58Å; I550-M554 VanDerWaalsContact CG2-SD 3.58Å; I550-M554 WeakPolarHBondContact O-CB 3.3Å; I550-M554 VanDerWaalsContact O-CG 3.25Å; I550-M554 WeakPolarHBondContact O-CG 3.3Å; I550-M554 PolarHBondContact O-N 3.18Å; I550-P717 HydrophobicContact CG2-CB 3.86Å; I550-P717 HydrophobicContact CG2-CG 4.21Å; I550-V720 HydrophobicContact CG2-CG2 3.61Å; I550-T723 HydrophobicContact CD1-CG2 4.23Å; I550-A724 VanDerWaalsContact CD1-CA 3.49Å; I550-A724 HydrophobicContact CD1-CB 3.69Å; I550-A727 HydrophobicContact CD1-CB 3.96Å
551A96.4Very high96.3Very high8 Ų828.9 Ų28.97%0.06615%0.152CC..Hα-helixtrans-59.1-43-18000000112M547 M554 A555 V681 P717M547-A551 VanDerWaalsContact O-CB 3.23Å; M547-A551 WeakPolarHBondContact O-CB 3.2Å; M547-A551 PolarHBondContact O-N 2.9Å; A551-M554 PolarHBondContact O-N 2.95Å; A551-A555 WeakPolarHBondContact O-CB 3.39Å; A551-A555 PolarHBondContact O-N 3.22Å; A551-V681 HydrophobicContact CB-CG1 3.74Å; A551-P717 HydrophobicContact CB-CG 4.44Å
552G97.3Very high96.5Very high0 Ų028.6 Ų28.60%015%0.149CC..Hα-helixtrans-61.3-47.217500000112.7S548 E549 I550 M554 A555 V593 A597S548-G552 PolarHBondContact O-N 3.07Å; E549-G552 PolarHBondContact O-N 2.91Å; I550-G552 VanDerWaalsContact C-N 3.33Å; I550-G552 PolarHBondContact O-N 2.92Å; G552-M554 PolarHBondContact O-N 2.95Å; G552-A555 PolarHBondContact O-N 3.08Å; G552-V593 WeakPolarHBondContact CA-O 3.1Å; G552-A597 WeakPolarHBondContact O-CA 3.41Å; G552-A597 WeakPolarHBondContact O-CB 3.37Å; G552-A597 PolarHBondContact O-N 3.05Å
553R98.1Very high96.6Very high105 Ų10527 Ų2740%0.39614%0.139SC..Hα-helixtrans-62.6-43.5178-67.6-179-167.4-173.910.8111.9E549 I550 N596 I600E549-R553 VanDerWaalsContact O-CG 3.29Å; E549-R553 WeakPolarHBondContact O-CG 3.42Å; E549-R553 PolarHBondContact O-N 3.11Å; I550-R553 PolarHBondContact O-N 3.36Å; R553-N596 HydrophobicContact CG-CB 3.94Å; R553-N596 PolarHBondContact NE-OD1 2.9Å; R553-N596 PolarHBondContact NH2-OD1 2.79Å; R553-I600 HydrophobicContact CB-CD1 4.41Å; R553-I600 HydrophobicContact CB-CG1 3.75Å; R553-I600 HydrophobicContact CG-CD1 4.12Å; R553-I600 HydrophobicContact CG-CG1 3.69Å
554M97.3Very high96.7Very high13 Ų1331.5 Ų31.56%0.06416%0.16CC..Hα-helixtrans-66-37.8177.7-70.4-179.274.900112I550 A551 G552 A556 Q557 I558 M716 A719 V720I550-M554 HydrophobicContact CG2-CG 4.16Å; I550-M554 HydrophobicContact CG2-SD 3.58Å; I550-M554 VanDerWaalsContact CG2-SD 3.58Å; I550-M554 WeakPolarHBondContact O-CB 3.3Å; I550-M554 VanDerWaalsContact O-CG 3.25Å; I550-M554 WeakPolarHBondContact O-CG 3.3Å; I550-M554 PolarHBondContact O-N 3.18Å; A551-M554 PolarHBondContact O-N 2.95Å; G552-M554 PolarHBondContact O-N 2.95Å; M554-A556 PolarHBondContact O-N 2.89Å; M554-Q557 PolarHBondContact O-N 3.29Å; M554-I558 HydrophobicContact CB-CD1 3.99Å; M554-I558 HydrophobicContact CE-CD1 4.09Å; M554-I558 VanDerWaalsContact O-CB 3.28Å; M554-I558 WeakPolarHBondContact O-CB 3.43Å; M554-I558 WeakPolarHBondContact O-CG1 3.35Å; M554-I558 PolarHBondContact O-N 2.99Å; M554-M716 HydrophobicContact CB-CE 4.06Å; M554-M716 WeakPolarHBondContact CE-O 3.31Å; M554-A719 HydrophobicContact CE-CB 3.93Å; M554-V720 HydrophobicContact CE-CG1 4.11Å; M554-V720 HydrophobicContact CE-CG2 4.22Å; M554-V720 HydrophobicContact SD-CG1 4.29Å; M554-V720 HydrophobicContact SD-CG2 3.5Å; M554-V720 VanDerWaalsContact SD-CG2 3.5Å
555A98.1Very high96.8Very high0 Ų037.6 Ų37.60%018%0.182CC..Hα-helixtrans-55.9-40.5-179.100000112.4A551 G552 G559 I650 V679 V681 M716A551-A555 WeakPolarHBondContact O-CB 3.39Å; A551-A555 PolarHBondContact O-N 3.22Å; G552-A555 PolarHBondContact O-N 3.08Å; A555-G559 PolarHBondContact O-N 3.45Å; A555-I650 HydrophobicContact CB-CD1 3.97Å; A555-I650 HydrophobicContact CB-CG1 4.32Å; A555-I650 HydrophobicContact CB-CG2 3.8Å; A555-V679 HydrophobicContact CB-CG1 3.83Å; A555-V681 HydrophobicContact CB-CG2 3.79Å; A555-M716 HydrophobicContact CB-CE 4Å
556A97.9Very high96.9Very high0 Ų042.2 Ų42.20%021%0.207CC..Hα-helixtrans-68.6-42.3175.400000112.7M554 A560 I600 A601 I650M554-A556 PolarHBondContact O-N 2.89Å; A556-A560 WeakPolarHBondContact O-CB 3.32Å; A556-A560 PolarHBondContact O-N 3.49Å; A556-I600 HydrophobicContact CB-CB 3.76Å; A556-I600 HydrophobicContact CB-CG2 3.63Å; A556-A601 HydrophobicContact CB-CB 4.24Å; A556-I650 HydrophobicContact CB-CD1 4.45Å
557Q97.5Very high96.8Very high109 Ų10944.1 Ų44.151%0.50922%0.216SC..Hα-helixtrans-66.2-46.5178.7-65.8173.6-2000111.9M554 A560 N561 I600M554-Q557 PolarHBondContact O-N 3.29Å; Q557-A560 WeakPolarHBondContact O-CB 3.49Å; Q557-A560 PolarHBondContact O-N 3.39Å; Q557-N561 PolarHBondContact O-N 3.38Å; Q557-I600 HydrophobicContact CG-CG2 4.1Å
558I96.9Very high96.5Very high25 Ų2544.6 Ų44.613%0.12822%0.223CC..Hα-helixtrans-63.8-47177.4-73167.7000109.9M554 A560 N561 F562 Y711 M716M554-I558 HydrophobicContact CB-CD1 3.99Å; M554-I558 HydrophobicContact CE-CD1 4.09Å; M554-I558 VanDerWaalsContact O-CB 3.28Å; M554-I558 WeakPolarHBondContact O-CB 3.43Å; M554-I558 WeakPolarHBondContact O-CG1 3.35Å; M554-I558 PolarHBondContact O-N 2.99Å; I558-A560 VanDerWaalsContact C-N 3.3Å; I558-A560 PolarHBondContact O-N 3.24Å; I558-N561 PolarHBondContact O-N 3.08Å; I558-N561 VanDerWaalsContact O-N 3.15Å; I558-F562 HydrophobicContact CG2-CD2 3.62Å; I558-F562 HydrophobicContact CG2-CE2 3.76Å; I558-F562 WeakPolarHBondContact O-CD2 3.41Å; I558-F562 PolarHBondContact O-N 3.15Å; I558-Y711 HydrophobicContact CD1-CE1 4.39Å; I558-Y711 HydrophobicContact CD1-CE2 4.44Å; I558-Y711 HydrophobicContact CG2-CD1 4.24Å; I558-Y711 HydrophobicContact CG2-CD2 3.57Å; I558-Y711 HydrophobicContact CG2-CE1 4.22Å; I558-Y711 HydrophobicContact CG2-CE2 3.53Å; I558-Y711 HydrophobicContact CG2-CG 3.93Å; I558-M716 HydrophobicContact CD1-CE 3.69Å
559G97.6Very high96.6Very high0 Ų043.9 Ų43.90%022%0.218CC..Hα-helixtrans-58.6-41.517600000112.5A555 L563A555-G559 PolarHBondContact O-N 3.45Å; G559-L563 WeakPolarHBondContact O-CB 3.41Å; G559-L563 WeakPolarHBondContact O-CG 3.47Å; G559-L563 PolarHBondContact O-N 3.01Å
560A97.9Very high96.6Very high26 Ų2645.6 Ų45.622%0.21522%0.221CC..Hα-helixtrans-63.1-41.7174.400000112.5A556 Q557 I558 L563 L574 L604A556-A560 WeakPolarHBondContact O-CB 3.32Å; A556-A560 PolarHBondContact O-N 3.49Å; Q557-A560 WeakPolarHBondContact O-CB 3.49Å; Q557-A560 PolarHBondContact O-N 3.39Å; I558-A560 VanDerWaalsContact C-N 3.3Å; I558-A560 PolarHBondContact O-N 3.24Å; A560-L563 WeakPolarHBondContact O-CB 3.2Å; A560-L563 PolarHBondContact O-N 3.35Å; A560-L574 HydrophobicContact CB-CD1 3.72Å; A560-L574 HydrophobicContact CB-CG 4.27Å; A560-L604 HydrophobicContact CB-CD1 4.28Å
561N97.3Very high96.6Very high72 Ų7247 Ų4739%0.38524%0.24SC..Hα-helixtrans-65.8-46.7177.6-176.2-96.2000112Q557 I558 L563 E564 N567Q557-N561 PolarHBondContact O-N 3.38Å; I558-N561 PolarHBondContact O-N 3.08Å; I558-N561 VanDerWaalsContact O-N 3.15Å; N561-L563 PolarHBondContact O-N 3.42Å; N561-E564 VanDerWaalsContact O-CB 3.31Å; N561-E564 WeakPolarHBondContact O-CB 3.32Å; N561-E564 WeakPolarHBondContact O-CG 3.49Å; N561-E564 PolarHBondContact O-N 3.06Å; N561-E564 VanDerWaalsContact O-N 3.09Å; N561-N567 PolarHBondContact O-ND2 2.95Å; N561-N567 PolarHBondContact OD1-ND2 3.37Å
562F97.6Very high96.6Very high25 Ų2548.2 Ų48.211%0.1125%0.247CC..Hα-helixtrans-72.2-14178.2-76.1-65.6000113.6I558 E564 N567 G569 V677 P701 T702 Y711I558-F562 HydrophobicContact CG2-CD2 3.62Å; I558-F562 HydrophobicContact CG2-CE2 3.76Å; I558-F562 WeakPolarHBondContact O-CD2 3.41Å; I558-F562 PolarHBondContact O-N 3.15Å; F562-E564 VanDerWaalsContact C-N 3.26Å; F562-N567 HydrophobicContact CD1-CB 3.87Å; F562-N567 HydrophobicContact CE1-CB 4.41Å; F562-G569 WeakPolarHBondContact O-CA 3.22Å; F562-G569 PolarHBondContact O-N 3.14Å; F562-V677 HydrophobicContact CB-CG1 4.11Å; F562-V677 HydrophobicContact CB-CG2 4.13Å; F562-P701 HydrophobicContact CE1-CG 4.29Å; F562-P701 HydrophobicContact CE2-CB 4.44Å; F562-P701 HydrophobicContact CE2-CG 4.45Å; F562-P701 HydrophobicContact CZ-CB 4.03Å; F562-P701 HydrophobicContact CZ-CG 3.59Å; F562-T702 HydrophobicContact CD1-CG2 3.65Å; F562-T702 HydrophobicContact CD2-CG2 4.05Å; F562-T702 HydrophobicContact CE1-CG2 3.52Å; F562-T702 HydrophobicContact CE2-CG2 3.92Å; F562-T702 HydrophobicContact CG-CG2 3.95Å; F562-T702 HydrophobicContact CZ-CG2 3.68Å; F562-Y711 AromaticContact CD2-CD2 3.94Å; F562-Y711 HydrophobicContact CD2-CD2 3.94Å; F562-Y711 AromaticContact CE2-CD2 3.5Å; F562-Y711 HydrophobicContact CE2-CD2 3.5Å; F562-Y711 VanDerWaalsContact CE2-CD2 3.5Å; F562-Y711 AromaticContact CE2-CE2 3.8Å; F562-Y711 HydrophobicContact CE2-CE2 3.8Å; F562-Y711 HydrophobicContact CZ-CD2 4.33Å
563L97.9Very high96.6Very high0 Ų053.5 Ų53.50%027%0.274CS..THydrogen-bonded Turntrans-70.7-21.3168.9-93.5170.4000112.9G559 A560 N561 G569 R570 G571 V572 L574 D647 L648 V677G559-L563 WeakPolarHBondContact O-CB 3.41Å; G559-L563 WeakPolarHBondContact O-CG 3.47Å; G559-L563 PolarHBondContact O-N 3.01Å; A560-L563 WeakPolarHBondContact O-CB 3.2Å; A560-L563 PolarHBondContact O-N 3.35Å; N561-L563 PolarHBondContact O-N 3.42Å; L563-G569 CarbonylContact O-C 3.55Å; L563-R570 HydrophobicContact CD2-CB 4.2Å; L563-R570 PolarHBondContact O-N 3.38Å; L563-G571 VanDerWaalsContact O-CA 3.31Å; L563-G571 WeakPolarHBondContact O-CA 3.47Å; L563-G571 PolarHBondContact O-N 3.05Å; L563-V572 HydrophobicContact CD2-CB 4.28Å; L563-V572 PolarHBondContact O-N 3.39Å; L563-L574 HydrophobicContact CD1-CD2 3.57Å; L563-L574 HydrophobicContact CD1-CG 4.17Å; L563-D647 HydrophobicContact CD1-CB 4.33Å; L563-D647 HydrophobicContact CD2-CB 4.05Å; L563-D647 WeakPolarHBondContact CD2-O 3.38Å; L563-L648 HydrophobicContact CD1-CB 3.92Å; L563-V677 HydrophobicContact CB-CG2 4.49Å; L563-V677 HydrophobicContact CD2-CG2 4.03Å; L563-V677 HydrophobicContact CG-CB 4.48Å; L563-V677 HydrophobicContact CG-CG2 3.87Å
564E97.4Very high96.6Very high95 Ų9548.8 Ų48.844%0.44426%0.257SS..SBendtrans-65.3140176.7-62.2179.8-178.400111.2N561 F562 V566 N567 G569N561-E564 VanDerWaalsContact O-CB 3.31Å; N561-E564 WeakPolarHBondContact O-CB 3.32Å; N561-E564 WeakPolarHBondContact O-CG 3.49Å; N561-E564 PolarHBondContact O-N 3.06Å; N561-E564 VanDerWaalsContact O-N 3.09Å; F562-E564 VanDerWaalsContact C-N 3.26Å; E564-V566 HydrophobicContact CB-CG2 4.04Å; E564-V566 PolarHBondContact O-N 3.07Å; E564-N567 PolarHBondContact O-N 2.79Å; E564-G569 PolarHBondContact O-N 3.08Å
565R95.5Very high96.6Very high147 Ų14750.6 Ų50.656%0.55527%0.271SS*.G310 helixtrans-61.5-32.3-174.3-176.761.5-170.7125.72.9112.9N567 G568 G569 H675R565-N567 PolarHBondContact O-N 3.23Å; R565-G568 PolarHBondContact NH1-O 3.46Å; R565-G568 PolarHBondContact O-N 2.95Å; R565-G568 VanDerWaalsContact O-N 3.11Å; R565-G569 WeakPolarHBondContact CD-O 3.37Å; R565-H675 PolarHBondContact NH1-CE1 3.35Å; R565-H675 VanDerWaalsContact NH1-CE1 3.27Å; R565-H675 PolarHBondContact NH1-ND1 2.98Å
566V94.5Very high96.5Very high124 Ų12450.9 Ų50.975%0.75227%0.274SS*.G310 helixtrans-62.9-25177.1-63.30000112.7E564E564-V566 HydrophobicContact CB-CG2 4.04Å; E564-V566 PolarHBondContact O-N 3.07Å
567N93.2Very high96.4Very high56 Ų5654.9 Ų54.930%0.29930%0.298SS..G310 helixtrans-98.711.1178.1-62.1-41000112.8N561 F562 E564 R565N561-N567 PolarHBondContact O-ND2 2.95Å; N561-N567 PolarHBondContact OD1-ND2 3.37Å; F562-N567 HydrophobicContact CD1-CB 3.87Å; F562-N567 HydrophobicContact CE1-CB 4.41Å; E564-N567 PolarHBondContact O-N 2.79Å; R565-N567 PolarHBondContact O-N 3.23Å
568G90.5Very high96.4Very high19 Ų1956.2 Ų56.220%0.19632%0.316CS..THydrogen-bonded Turntrans93.5-13.1178.200000114.9R565R565-G568 PolarHBondContact NH1-O 3.46Å; R565-G568 PolarHBondContact O-N 2.95Å; R565-G568 VanDerWaalsContact O-N 3.11Å
569G96.4Very high96.3Very high0 Ų059.4 Ų59.40%036%0.355CS..SBendtrans-70.1-178.2-179.700000115.2F562 L563 E564 R565 G571 H675F562-G569 WeakPolarHBondContact O-CA 3.22Å; F562-G569 PolarHBondContact O-N 3.14Å; L563-G569 CarbonylContact O-C 3.55Å; E564-G569 PolarHBondContact O-N 3.08Å; R565-G569 WeakPolarHBondContact CD-O 3.37Å; G569-G571 PolarHBondContact O-N 3.44Å; G569-H675 CarbonylContact C-O 3.53Å; G569-H675 WeakPolarHBondContact CA-O 3.32Å
570R96.3Very high96.2Very high115 Ų11563.8 Ų63.843%0.43438%0.382SS..  trans-66.7-19.5-174.4-164.8174.3-175.9178.18.2114.4L563 V572 D647 P673 H675L563-R570 HydrophobicContact CD2-CB 4.2Å; L563-R570 PolarHBondContact O-N 3.38Å; R570-V572 HydrophobicContact CB-CG2 4.11Å; R570-V572 HydrophobicContact CG-CG2 4.03Å; R570-D647 WeakPolarHBondContact CD-OD1 3.31Å; R570-D647 IonicContact CZ-OD1 2.68Å; R570-D647 IonicContact NE-OD1 2.68Å; R570-D647 IonicContact NH1-OD1 2.82Å; R570-D647 PolarHBondContact NH1-OD1 3.39Å; R570-P673 VanDerWaalsContact CZ-CB 3.45Å; R570-H675 HydrophobicContact CB-CB 4.3Å; R570-H675 WeakPolarHBondContact CB-O 3.32Å; R570-H675 PolarHBondContact N-O 3.22Å
571G97Very high96.1Very high47 Ų4766.7 Ų66.749%0.48541%0.406SS..  trans82.937.9-173.800000113.1L563 G569L563-G571 VanDerWaalsContact O-CA 3.31Å; L563-G571 WeakPolarHBondContact O-CA 3.47Å; L563-G571 PolarHBondContact O-N 3.05Å; G569-G571 PolarHBondContact O-N 3.44Å
572V97.1Very high96.1Very high34 Ų3469.7 Ų69.721%0.20641%0.412CS..  trans-105.5123.3-178.5174.50000110.3L563 R570 D647L563-V572 HydrophobicContact CD2-CB 4.28Å; L563-V572 PolarHBondContact O-N 3.39Å; R570-V572 HydrophobicContact CB-CG2 4.11Å; R570-V572 HydrophobicContact CG-CG2 4.03Å; V572-D647 HydrophobicContact CG1-CB 4.48Å
573L97.5Very high96.2Very high111 Ų11168.5 Ų68.558%0.58141%0.407SS*.  trans-83.5117.4166.3179.565000108.6S575 G576 V577L573-S575 VanDerWaalsContact C-N 3.27Å; L573-S575 WeakPolarHBondContact CD2-OG 3.02Å; L573-S575 WeakPolarHBondContact CG-OG 3.49Å; L573-S575 PolarHBondContact O-N 2.63Å; L573-G576 PolarHBondContact O-N 2.83Å; L573-V577 HydrophobicContact CD2-CG1 4.38Å
574L97.6Very high96.2Very high7 Ų770.9 Ų70.94%0.03742%0.419CS..THydrogen-bonded Turntrans-54.6-40-173.3-74.3-174.5000113.8A560 L563 G576 G583 V585 L604 A606 L648A560-L574 HydrophobicContact CB-CD1 3.72Å; A560-L574 HydrophobicContact CB-CG 4.27Å; L563-L574 HydrophobicContact CD1-CD2 3.57Å; L563-L574 HydrophobicContact CD1-CG 4.17Å; L574-G576 PolarHBondContact O-N 3.34Å; L574-G583 PolarHBondContact O-N 2.87Å; L574-V585 HydrophobicContact CD1-CG2 4.24Å; L574-V585 HydrophobicContact CD2-CG2 3.71Å; L574-L604 HydrophobicContact CD1-CD1 4.03Å; L574-A606 HydrophobicContact CB-CB 4.16Å; L574-A606 HydrophobicContact CD2-CB 4.34Å; L574-L648 HydrophobicContact CD1-CD2 4.5Å
575S97.4Very high96.3Very high50 Ų5066.4 Ų66.435%0.3540%0.399SS..THydrogen-bonded Turntrans-67.1-19.8178.561.80000114L573 L604L573-S575 VanDerWaalsContact C-N 3.27Å; L573-S575 WeakPolarHBondContact CD2-OG 3.02Å; L573-S575 WeakPolarHBondContact CG-OG 3.49Å; L573-S575 PolarHBondContact O-N 2.63Å; S575-L604 VanDerWaalsContact CA-O 3.22Å; S575-L604 WeakPolarHBondContact CA-O 3.4Å; S575-L604 WeakPolarHBondContact CB-O 3.45Å; S575-L604 PolarHBondContact N-O 3.44Å
576G95.7Very high96.4Very high7 Ų759.6 Ų59.67%0.07237%0.373CS..  trans52.6-156.2-155.600000111.3L573 L574L573-G576 PolarHBondContact O-N 2.83Å; L574-G576 PolarHBondContact O-N 3.34Å
577V96.4Very high96.6Very high83 Ų8353.7 Ų53.750%0.50334%0.337SS..  trans-145.2165.3166.8-67.40000107.6L573 G579 V580L573-V577 HydrophobicContact CD2-CG1 4.38Å; V577-G579 PolarHBondContact O-N 3.17Å; V577-G579 VanDerWaalsContact O-N 3.1Å; V577-V580 HydrophobicContact CG2-CB 3.79Å; V577-V580 HydrophobicContact CG2-CG2 3.56Å; V577-V580 PolarHBondContact O-N 2.86Å; V577-V580 VanDerWaalsContact O-O 3.12Å
578P96.2Very high96.8Very high137 Ų13751 Ų5189%0.8932%0.323SS*.THydrogen-bonded Turntrans-50.6121.6176.4-28.836.6000112.3
579G95.3Very high97.1Very high92 Ų9250.4 Ų50.495%0.94832%0.317SS*.THydrogen-bonded Turntrans90.5-3.1-176.300000115.9V577V577-G579 PolarHBondContact O-N 3.17Å; V577-G579 VanDerWaalsContact O-N 3.1Å
580V96.2Very high97.1Very high93 Ų9350.4 Ų50.456%0.56432%0.317SS*.SBendtrans-121.4138.6178-178.90000109.7V577V577-V580 HydrophobicContact CG2-CB 3.79Å; V577-V580 HydrophobicContact CG2-CG2 3.56Å; V577-V580 PolarHBondContact O-N 2.86Å; V577-V580 VanDerWaalsContact O-O 3.12Å
581A96.1Very high97Very high87 Ų8746.5 Ų46.572%0.71931%0.312SS*.PPolyproline II helixtrans-60.3145.3-179.800000112.2
582R97.4Very high96.8Very high134 Ų13446.9 Ų46.951%0.50631%0.305SS..PPolyproline II helixtrans-73.6155.9170-66.5167.7176.5-167.73110.2G605 N607R582-G605 WeakPolarHBondContact CD-O 3.49Å; R582-G605 WeakPolarHBondContact CG-O 3.34Å; R582-G605 PolarHBondContact NE-O 3.04Å; R582-N607 WeakPolarHBondContact CD-OD1 3.06Å
583G97.9Very high96.8Very high0 Ų046.1 Ų46.10%030%0.301CS..PPolyproline II helixtrans-73148.8169.800000111.9L574 N607 D647L574-G583 PolarHBondContact O-N 2.87Å; G583-N607 PolarHBondContact O-N 3.21Å; G583-D647 WeakPolarHBondContact CA-OD2 3.43Å
584N98.5Very high96.8Very high50 Ų5040.9 Ų40.927%0.26727%0.273SS..EExtended strand (participates in β ladder)trans-97.9123175.6-60.4-42000110.7N607 T645 D647 L648N584-N607 WeakPolarHBondContact OD1-CB 3.49Å; N584-N607 PolarHBondContact OD1-ND2 3Å; N584-T645 WeakPolarHBondContact CB-O 3.39Å; N584-T645 PolarHBondContact ND2-O 2.9Å; N584-D647 PolarHBondContact N-OD2 3.2Å; N584-D647 PolarHBondContact O-N 2.98Å; N584-L648 PolarHBondContact O-N 3.05Å
585V98.7Very high96.7Very high1 Ų142.8 Ų42.81%0.00628%0.282CS..EExtended strand (participates in β ladder)trans-113.2121.8178.5-179.20000109.4L574 V587 A601 A606 N607 V608 T609 L648 I650L574-V585 HydrophobicContact CD1-CG2 4.24Å; L574-V585 HydrophobicContact CD2-CG2 3.71Å; V585-V587 HydrophobicContact CG1-CG2 4.23Å; V585-A601 HydrophobicContact CB-CB 4.26Å; V585-A601 HydrophobicContact CG1-CB 3.96Å; V585-A601 HydrophobicContact CG2-CB 4.17Å; V585-A606 HydrophobicContact CB-CB 4.45Å; V585-A606 HydrophobicContact CG2-CB 3.65Å; V585-N607 PolarHBondContact N-O 3.05Å; V585-V608 HydrophobicContact CB-CG2 4.39Å; V585-V608 WeakPolarHBondContact O-CA 3.41Å; V585-T609 PolarHBondContact O-N 3.22Å; V585-L648 CarbonylContact C-O 3.54Å; V585-L648 WeakPolarHBondContact CA-O 3.44Å; V585-L648 HydrophobicContact CG1-CD2 4.17Å; V585-L648 HydrophobicContact CG1-CG 4.28Å; V585-L648 HydrophobicContact CG2-CB 4.23Å; V585-L648 HydrophobicContact CG2-CD2 4.16Å; V585-I650 HydrophobicContact CG1-CD1 4.33Å
586V98.7Very high96.8Very high4 Ų440.6 Ų40.62%0.02427%0.267CS..EExtended strand (participates in β ladder)trans-105.8127.3173.9176.80000109.4I588 T609 M611 V642 A646 L648 V649 I650V586-I588 HydrophobicContact CG1-CG1 4.12Å; V586-T609 CarbonylContact C-O 3.6Å; V586-T609 WeakPolarHBondContact CA-O 3.37Å; V586-M611 HydrophobicContact CG1-SD 4.17Å; V586-V642 HydrophobicContact CG1-CG2 3.74Å; V586-V642 HydrophobicContact CG2-CB 4.03Å; V586-V642 HydrophobicContact CG2-CG2 3.98Å; V586-A646 HydrophobicContact CB-CB 4.29Å; V586-A646 HydrophobicContact CG2-CB 3.72Å; V586-L648 PolarHBondContact N-O 3.14Å; V586-V649 HydrophobicContact CB-CG2 4.46Å; V586-V649 CarbonylContact O-C 3.43Å; V586-V649 VanDerWaalsContact O-CA 3.32Å; V586-V649 WeakPolarHBondContact O-CA 3.49Å; V586-I650 PolarHBondContact O-N 3.14Å
587V98.7Very high96.9Very high0 Ų040.2 Ų40.20%026%0.263CS..EExtended strand (participates in β ladder)trans-114.3117.7176.2-177.80000108.7V585 G594 A597 A598 V608 T609 I610 M611 I650 A652V585-V587 HydrophobicContact CG1-CG2 4.23Å; V587-G594 VanDerWaalsContact CG1-CA 3.47Å; V587-A597 HydrophobicContact CG1-CB 4.45Å; V587-A597 HydrophobicContact CG2-CB 4.34Å; V587-A598 HydrophobicContact CG2-CB 4.48Å; V587-V608 HydrophobicContact CG2-CG1 4.44Å; V587-T609 PolarHBondContact N-O 2.99Å; V587-I610 HydrophobicContact CB-CB 4.4Å; V587-I610 HydrophobicContact CB-CD1 4.48Å; V587-I610 HydrophobicContact CB-CG1 4.11Å; V587-I610 HydrophobicContact CG1-CD1 4.18Å; V587-I610 HydrophobicContact CG1-CG1 4.14Å; V587-I610 CarbonylContact O-C 3.6Å; V587-I610 WeakPolarHBondContact O-CA 3.09Å; V587-M611 PolarHBondContact O-N 3.31Å; V587-I650 HydrophobicContact CG2-CB 4.43Å; V587-A652 HydrophobicContact CG1-CB 4.41Å
588I98.3Very high97Very high0 Ų036.3 Ų36.30%024%0.239CC..EExtended strand (participates in β ladder)trans-100.5107.3179.4-52.8177.8000108.3V586 I639 V649 I650 A652 V653 L663 V664 I688V586-I588 HydrophobicContact CG1-CG1 4.12Å; I588-I639 HydrophobicContact CD1-CG2 4.24Å; I588-V649 HydrophobicContact CD1-CG1 4.14Å; I588-V649 HydrophobicContact CG1-CG1 4.48Å; I588-I650 PolarHBondContact N-O 2.81Å; I588-A652 CarbonylContact O-C 3.43Å; I588-A652 WeakPolarHBondContact O-CA 3.44Å; I588-A652 WeakPolarHBondContact O-CB 3.13Å; I588-A652 PolarHBondContact O-N 3.02Å; I588-V653 HydrophobicContact CG2-CG2 4.03Å; I588-V653 WeakPolarHBondContact O-CG2 3.29Å; I588-V653 PolarHBondContact O-N 3.39Å; I588-L663 HydrophobicContact CG2-CD1 4.27Å; I588-V664 HydrophobicContact CD1-CG2 3.63Å; I588-I688 HydrophobicContact CB-CD1 3.98Å; I588-I688 HydrophobicContact CD1-CD1 4.29Å; I588-I688 HydrophobicContact CG2-CD1 4.04Å
589G96.5Very high97Very high6 Ų635.5 Ų35.56%0.06222%0.222CC..  trans114.1120.4-174.400000111.4G594 M611G589-G594 WeakPolarHBondContact O-CA 3.32Å; G589-M611 CarbonylContact C-O 3.59Å; G589-M611 VanDerWaalsContact CA-O 3.31Å; G589-M611 WeakPolarHBondContact CA-O 3.43Å; G589-M611 PolarHBondContact N-O 3.46Å
590G95.4Very high97.2Very high0 Ų033 Ų330%019%0.187CC..  trans-915.3-17700000114.9D612 R617G590-D612 WeakPolarHBondContact CA-OD2 3.38Å; G590-D612 PolarHBondContact N-OD2 3.35Å; G590-R617 VanDerWaalsContact O-CZ 3.25Å; G590-R617 PolarHBondContact O-NE 3.2Å; G590-R617 PolarHBondContact O-NH2 2.79Å
591G93.5Very high97.3Very high33 Ų3328.6 Ų28.634%0.3416%0.16SC..SBendtrans-67.3-159.4-177.400000114.7G594 M595G591-G594 PolarHBondContact O-N 3.41Å; G591-M595 VanDerWaalsContact O-CB 3.29Å; G591-M595 WeakPolarHBondContact O-CB 3.49Å; G591-M595 PolarHBondContact O-N 3.3Å
592V94.2Very high97.3Very high56 Ų5625.9 Ų25.934%0.33914%0.137SC..Hα-helixtrans-61.6-46.9-178.1179.30000111.6E549 N596E549-V592 HydrophobicContact CB-CG1 4.42Å; E549-V592 HydrophobicContact CG-CG1 3.49Å; E549-V592 VanDerWaalsContact CG-CG1 3.49Å; V592-N596 WeakPolarHBondContact O-CB 3.44Å; V592-N596 PolarHBondContact O-N 3.42Å; V592-N596 PolarHBondContact O-ND2 3.32Å
593V95.9Very high97.3Very high18 Ų1822.9 Ų22.911%0.10915%0.148CC..Hα-helixtrans-57.7-54.7175.91760000110.1S548 G552 M595 N596 A597 A652 V681S548-V593 WeakPolarHBondContact O-CA 3.4Å; G552-V593 WeakPolarHBondContact CA-O 3.1Å; V593-M595 PolarHBondContact O-N 3.05Å; V593-N596 PolarHBondContact O-N 3.15Å; V593-A597 WeakPolarHBondContact O-CB 3.49Å; V593-A597 PolarHBondContact O-N 3.14Å; V593-A652 HydrophobicContact CB-CB 3.92Å; V593-A652 HydrophobicContact CG1-CB 3.56Å; V593-V681 HydrophobicContact CG1-CB 4.01Å; V593-V681 HydrophobicContact CG1-CG1 3.74Å; V593-V681 HydrophobicContact CG1-CG2 4.05Å; V593-V681 HydrophobicContact CG2-CG1 4.33Å
594G97.1Very high97.2Very high0 Ų026.4 Ų26.40%017%0.166CC..Hα-helixtrans-64-41.7-174.500000113.8V587 G589 G591 N596 A597 A598V587-G594 VanDerWaalsContact CG1-CA 3.47Å; G589-G594 WeakPolarHBondContact O-CA 3.32Å; G591-G594 PolarHBondContact O-N 3.41Å; G594-N596 VanDerWaalsContact C-N 3.33Å; G594-N596 PolarHBondContact O-N 3.45Å; G594-A597 PolarHBondContact O-N 3.09Å; G594-A598 WeakPolarHBondContact O-CB 3.48Å; G594-A598 PolarHBondContact O-N 2.94Å
595M97.3Very high97.1Very high47 Ų4724.9 Ų24.923%0.23216%0.163CC..Hα-helixtrans-60.3-42.9175.2-176.6-176.274.300111.8G591 V593 K599 L621 I624 F625G591-M595 VanDerWaalsContact O-CB 3.29Å; G591-M595 WeakPolarHBondContact O-CB 3.49Å; G591-M595 PolarHBondContact O-N 3.3Å; V593-M595 PolarHBondContact O-N 3.05Å; M595-K599 VanDerWaalsContact O-CB 3.32Å; M595-K599 WeakPolarHBondContact O-CB 3.33Å; M595-K599 PolarHBondContact O-N 3.05Å; M595-L621 HydrophobicContact CB-CD2 4.01Å; M595-L621 HydrophobicContact CG-CD2 3.88Å; M595-I624 HydrophobicContact SD-CD1 4.1Å; M595-F625 HydrophobicContact CG-CE2 4.27Å; M595-F625 HydrophobicContact CG-CZ 4.38Å
596N98.2Very high97.1Very high4 Ų425.2 Ų25.22%0.02117%0.165CC..Hα-helixtrans-70.7-38.2178.6-83.6-86.7000112.2R553 V592 V593 G594 K599 I600R553-N596 HydrophobicContact CG-CB 3.94Å; R553-N596 PolarHBondContact NE-OD1 2.9Å; R553-N596 PolarHBondContact NH2-OD1 2.79Å; V592-N596 WeakPolarHBondContact O-CB 3.44Å; V592-N596 PolarHBondContact O-N 3.42Å; V592-N596 PolarHBondContact O-ND2 3.32Å; V593-N596 PolarHBondContact O-N 3.15Å; G594-N596 VanDerWaalsContact C-N 3.33Å; G594-N596 PolarHBondContact O-N 3.45Å; N596-K599 PolarHBondContact O-N 3.45Å; N596-I600 WeakPolarHBondContact O-CG1 3.11Å; N596-I600 PolarHBondContact O-N 3.33Å; N596-I600 VanDerWaalsContact O-N 3.08Å
597A98.3Very high97.1Very high0 Ų028.4 Ų28.40%018%0.182CC..Hα-helixtrans-61.4-49.5173.600000111.6G552 V587 V593 G594 K599 I600 A601 I650G552-A597 WeakPolarHBondContact O-CA 3.41Å; G552-A597 WeakPolarHBondContact O-CB 3.37Å; G552-A597 PolarHBondContact O-N 3.05Å; V587-A597 HydrophobicContact CG1-CB 4.45Å; V587-A597 HydrophobicContact CG2-CB 4.34Å; V593-A597 WeakPolarHBondContact O-CB 3.49Å; V593-A597 PolarHBondContact O-N 3.14Å; G594-A597 PolarHBondContact O-N 3.09Å; A597-K599 VanDerWaalsContact C-N 3.31Å; A597-K599 PolarHBondContact O-N 2.68Å; A597-I600 PolarHBondContact O-N 2.7Å; A597-A601 WeakPolarHBondContact O-CB 3.3Å; A597-A601 PolarHBondContact O-N 3.28Å; A597-I650 HydrophobicContact CB-CD1 3.83Å; A597-I650 HydrophobicContact CB-CG2 4.16Å
598A98.1Very high97.1Very high0 Ų028.7 Ų28.70%018%0.184CC..Hα-helixtrans-59.9-41.5176.200000111.8V587 G594 I600 A601 A602 V608 I610 F625 I629V587-A598 HydrophobicContact CG2-CB 4.48Å; G594-A598 WeakPolarHBondContact O-CB 3.48Å; G594-A598 PolarHBondContact O-N 2.94Å; A598-I600 PolarHBondContact O-N 2.98Å; A598-A601 PolarHBondContact O-N 3.33Å; A598-A602 WeakPolarHBondContact O-CB 3.3Å; A598-A602 PolarHBondContact O-N 3.17Å; A598-V608 HydrophobicContact CB-CG1 3.86Å; A598-I610 HydrophobicContact CB-CD1 4.02Å; A598-F625 HydrophobicContact CB-CZ 4.23Å; A598-I629 HydrophobicContact CB-CD1 4.1Å
599K97.7Very high97.1Very high120 Ų12029.6 Ų29.652%0.52219%0.19SC..Hα-helixtrans-59-47176.9-176.9175.9-179.9175.10112.8M595 N596 A597 G603 F625M595-K599 VanDerWaalsContact O-CB 3.32Å; M595-K599 WeakPolarHBondContact O-CB 3.33Å; M595-K599 PolarHBondContact O-N 3.05Å; N596-K599 PolarHBondContact O-N 3.45Å; A597-K599 VanDerWaalsContact C-N 3.31Å; A597-K599 PolarHBondContact O-N 2.68Å; K599-G603 PolarHBondContact O-N 2.87Å; K599-F625 HydrophobicContact CB-CE1 3.91Å; K599-F625 HydrophobicContact CB-CZ 3.95Å; K599-F625 HydrophobicContact CG-CE1 4.38Å
600I98.2Very high97.2Very high41 Ų4129.3 Ų29.321%0.2119%0.187CC..Hα-helixtrans-72-42.8179.4-62.2-55000111.1R553 A556 Q557 N596 A597 A598 A602 G603 L604R553-I600 HydrophobicContact CB-CD1 4.41Å; R553-I600 HydrophobicContact CB-CG1 3.75Å; R553-I600 HydrophobicContact CG-CD1 4.12Å; R553-I600 HydrophobicContact CG-CG1 3.69Å; A556-I600 HydrophobicContact CB-CB 3.76Å; A556-I600 HydrophobicContact CB-CG2 3.63Å; Q557-I600 HydrophobicContact CG-CG2 4.1Å; N596-I600 WeakPolarHBondContact O-CG1 3.11Å; N596-I600 PolarHBondContact O-N 3.33Å; N596-I600 VanDerWaalsContact O-N 3.08Å; A597-I600 PolarHBondContact O-N 2.7Å; A598-I600 PolarHBondContact O-N 2.98Å; I600-A602 PolarHBondContact O-N 3.3Å; I600-G603 CarbonylContact O-C 3.57Å; I600-G603 PolarHBondContact O-N 2.9Å; I600-L604 HydrophobicContact CG2-CD1 4.25Å; I600-L604 HydrophobicContact CG2-CG 4.48Å; I600-L604 WeakPolarHBondContact O-CG 3.48Å; I600-L604 PolarHBondContact O-N 2.94Å
601A98.2Very high97.3Very high0 Ų029.3 Ų29.30%019%0.187CC..Hα-helixtrans-61.1-43.5178.100000112.4A556 V585 A597 A598 L604 G605 A606 V608A556-A601 HydrophobicContact CB-CB 4.24Å; V585-A601 HydrophobicContact CB-CB 4.26Å; V585-A601 HydrophobicContact CG1-CB 3.96Å; V585-A601 HydrophobicContact CG2-CB 4.17Å; A597-A601 WeakPolarHBondContact O-CB 3.3Å; A597-A601 PolarHBondContact O-N 3.28Å; A598-A601 PolarHBondContact O-N 3.33Å; A601-L604 PolarHBondContact O-N 3.28Å; A601-G605 PolarHBondContact O-N 3.29Å; A601-A606 VanDerWaalsContact O-CB 3.31Å; A601-A606 WeakPolarHBondContact O-CB 3.41Å; A601-A606 PolarHBondContact O-N 2.96Å; A601-A606 VanDerWaalsContact O-N 3.1Å; A601-V608 HydrophobicContact CB-CG2 3.73Å
602A97.1Very high97.5Very high30 Ų3029 Ų2925%0.24818%0.177CC..Hα-helixtrans-65.8-39.4174.400000111.5A598 I600 L604 G605 V608 I629A598-A602 WeakPolarHBondContact O-CB 3.3Å; A598-A602 PolarHBondContact O-N 3.17Å; I600-A602 PolarHBondContact O-N 3.3Å; A602-L604 VanDerWaalsContact C-N 3.27Å; A602-L604 PolarHBondContact O-N 3.45Å; A602-G605 WeakPolarHBondContact O-CA 3.33Å; A602-G605 PolarHBondContact O-N 3.26Å; A602-V608 HydrophobicContact CB-CG2 4.09Å; A602-I629 HydrophobicContact CB-CG2 3.96Å
603G96.4Very high97.5Very high70 Ų7031.4 Ų31.472%0.72219%0.192SC*.Hα-helixtrans-63.2-29.4173.800000113.9K599 I600 G605K599-G603 PolarHBondContact O-N 2.87Å; I600-G603 CarbonylContact O-C 3.57Å; I600-G603 PolarHBondContact O-N 2.9Å; G603-G605 PolarHBondContact O-N 3.23Å
604L96.5Very high97.4Very high74 Ų7432.7 Ų32.739%0.38720%0.202SC..THydrogen-bonded Turntrans-76.9-4.8169.8-68.7172.1000112.9A560 L574 S575 I600 A601 A602A560-L604 HydrophobicContact CB-CD1 4.28Å; L574-L604 HydrophobicContact CD1-CD1 4.03Å; S575-L604 VanDerWaalsContact CA-O 3.22Å; S575-L604 WeakPolarHBondContact CA-O 3.4Å; S575-L604 WeakPolarHBondContact CB-O 3.45Å; S575-L604 PolarHBondContact N-O 3.44Å; I600-L604 HydrophobicContact CG2-CD1 4.25Å; I600-L604 HydrophobicContact CG2-CG 4.48Å; I600-L604 WeakPolarHBondContact O-CG 3.48Å; I600-L604 PolarHBondContact O-N 2.94Å; A601-L604 PolarHBondContact O-N 3.28Å; A602-L604 VanDerWaalsContact C-N 3.27Å; A602-L604 PolarHBondContact O-N 3.45Å
605G96.4Very high97.3Very high19 Ų1936 Ų3620%0.19622%0.221CC..THydrogen-bonded Turntrans86.215.8178.200000115.3R582 A601 A602 G603R582-G605 WeakPolarHBondContact CD-O 3.49Å; R582-G605 WeakPolarHBondContact CG-O 3.34Å; R582-G605 PolarHBondContact NE-O 3.04Å; A601-G605 PolarHBondContact O-N 3.29Å; A602-G605 WeakPolarHBondContact O-CA 3.33Å; A602-G605 PolarHBondContact O-N 3.26Å; G603-G605 PolarHBondContact O-N 3.23Å
606A98.2Very high97.2Very high7 Ų738 Ų386%0.05824%0.238CC..  trans-71.5161.4176.400000113L574 V585 A601 V608L574-A606 HydrophobicContact CB-CB 4.16Å; L574-A606 HydrophobicContact CD2-CB 4.34Å; V585-A606 HydrophobicContact CB-CB 4.45Å; V585-A606 HydrophobicContact CG2-CB 3.65Å; A601-A606 VanDerWaalsContact O-CB 3.31Å; A601-A606 WeakPolarHBondContact O-CB 3.41Å; A601-A606 PolarHBondContact O-N 2.96Å; A601-A606 VanDerWaalsContact O-N 3.1Å; A606-V608 HydrophobicContact CB-CG2 4.19Å
607N98.2Very high97Very high71 Ų7140.1 Ų40.138%0.3825%0.246SC..EExtended strand (participates in β ladder)trans-82.4115.5161.2-65.9-26.9000108.5R582 G583 N584 V585R582-N607 WeakPolarHBondContact CD-OD1 3.06Å; G583-N607 PolarHBondContact O-N 3.21Å; N584-N607 WeakPolarHBondContact OD1-CB 3.49Å; N584-N607 PolarHBondContact OD1-ND2 3Å; V585-N607 PolarHBondContact N-O 3.05Å
608V98.6Very high96.9Very high7 Ų740.8 Ų40.84%0.04225%0.249CC..EExtended strand (participates in β ladder)trans-110.9128.6-173.4-176.30000111V585 V587 A598 A601 A602 A606 I629 Q630V585-V608 HydrophobicContact CB-CG2 4.39Å; V585-V608 WeakPolarHBondContact O-CA 3.41Å; V587-V608 HydrophobicContact CG2-CG1 4.44Å; A598-V608 HydrophobicContact CB-CG1 3.86Å; A601-V608 HydrophobicContact CB-CG2 3.73Å; A602-V608 HydrophobicContact CB-CG2 4.09Å; A606-V608 HydrophobicContact CB-CG2 4.19Å; V608-I629 HydrophobicContact CB-CB 4.18Å; V608-I629 HydrophobicContact CB-CG2 3.93Å; V608-I629 HydrophobicContact CG1-CB 4.39Å; V608-I629 HydrophobicContact CG1-CG2 4.26Å; V608-Q630 PolarHBondContact O-N 3.17Å
609T98.6Very high96.8Very high19 Ų1947.5 Ų47.512%0.11728%0.279CS..EExtended strand (participates in β ladder)trans-115117.2166.8-54.70000109.5V585 V586 V587 M611 Q630 L632 V642V585-T609 PolarHBondContact O-N 3.22Å; V586-T609 CarbonylContact C-O 3.6Å; V586-T609 WeakPolarHBondContact CA-O 3.37Å; V587-T609 PolarHBondContact N-O 2.99Å; T609-M611 HydrophobicContact CG2-CG 4.39Å; T609-Q630 CarbonylContact C-O 3.55Å; T609-Q630 WeakPolarHBondContact CA-O 3.5Å; T609-Q630 HydrophobicContact CG2-CB 4.33Å; T609-Q630 HydrophobicContact CG2-CG 4.15Å; T609-Q630 PolarHBondContact OG1-OE1 3.28Å; T609-L632 HydrophobicContact CG2-CB 3.94Å; T609-L632 HydrophobicContact CG2-CD2 4.15Å; T609-V642 HydrophobicContact CG2-CG1 4.42Å
610I98.4Very high96.7Very high0 Ų046.6 Ų46.60%028%0.276CS..EExtended strand (participates in β ladder)trans-102.8132.6173.6-167.8158.3000110.6V587 A598 L621 I629 Q630 T631 L632V587-I610 HydrophobicContact CB-CB 4.4Å; V587-I610 HydrophobicContact CB-CD1 4.48Å; V587-I610 HydrophobicContact CB-CG1 4.11Å; V587-I610 HydrophobicContact CG1-CD1 4.18Å; V587-I610 HydrophobicContact CG1-CG1 4.14Å; V587-I610 CarbonylContact O-C 3.6Å; V587-I610 WeakPolarHBondContact O-CA 3.09Å; A598-I610 HydrophobicContact CB-CD1 4.02Å; I610-L621 HydrophobicContact CD1-CD1 3.86Å; I610-L621 HydrophobicContact CD1-CD2 4.32Å; I610-L621 HydrophobicContact CG1-CD1 4.21Å; I610-L621 HydrophobicContact CG2-CD1 4.09Å; I610-I629 HydrophobicContact CB-CD1 4.27Å; I610-I629 HydrophobicContact CG2-CD1 3.55Å; I610-I629 HydrophobicContact CG2-CG1 4.34Å; I610-Q630 PolarHBondContact N-O 2.81Å; I610-T631 HydrophobicContact CG2-CG2 3.92Å; I610-T631 WeakPolarHBondContact O-CA 3.44Å; I610-L632 PolarHBondContact O-N 3.17Å
611M98.1Very high96.6Very high0 Ų044.7 Ų44.70%027%0.266CS..EExtended strand (participates in β ladder)trans-116.5136.4-176.1-52.6-175.180.700111.9V586 V587 G589 T609 L632 N638 I639 V642V586-M611 HydrophobicContact CG1-SD 4.17Å; V587-M611 PolarHBondContact O-N 3.31Å; G589-M611 CarbonylContact C-O 3.59Å; G589-M611 VanDerWaalsContact CA-O 3.31Å; G589-M611 WeakPolarHBondContact CA-O 3.43Å; G589-M611 PolarHBondContact N-O 3.46Å; T609-M611 HydrophobicContact CG2-CG 4.39Å; M611-L632 VanDerWaalsContact CA-O 3.24Å; M611-L632 WeakPolarHBondContact CA-O 3.46Å; M611-L632 HydrophobicContact CE-CD2 3.88Å; M611-L632 HydrophobicContact CE-CG 4.13Å; M611-L632 HydrophobicContact CG-CB 4.33Å; M611-N638 HydrophobicContact CE-CB 3.61Å; M611-I639 HydrophobicContact CE-CB 4.45Å; M611-I639 HydrophobicContact CE-CG1 3.78Å; M611-I639 HydrophobicContact SD-CG1 4.04Å; M611-V642 HydrophobicContact CE-CG2 4.3Å; M611-V642 HydrophobicContact SD-CG2 3.63Å
612D97Very high96.5Very high27 Ų2748 Ų4814%0.14428%0.284CS..EExtended strand (participates in β ladder)trans-151.4156.5174.3-157-71.7000109.9G590 S614 L618 L632 S634G590-D612 WeakPolarHBondContact CA-OD2 3.38Å; G590-D612 PolarHBondContact N-OD2 3.35Å; D612-S614 VanDerWaalsContact OD1-CB 3.24Å; D612-S614 WeakPolarHBondContact OD1-CB 3.28Å; D612-S614 PolarHBondContact OD1-N 3.32Å; D612-L618 HydrophobicContact CB-CD2 3.64Å; D612-L618 HydrophobicContact CB-CG 4.08Å; D612-L632 PolarHBondContact N-O 2.78Å; D612-S634 PolarHBondContact O-N 3.42Å
613V95.6Very high96.4Very high105 Ų10553.2 Ų53.264%0.63631%0.307SS*.SBendtrans-81.4-21.5174.1-63.10000111.8V615V613-V615 PolarHBondContact O-N 3.24Å
614S92.8Very high96.3Very high46 Ų4654.5 Ų54.532%0.32230%0.296SS..  trans-88.5102.5-177.5177.60000111.1D612 P616 R617 L618D612-S614 VanDerWaalsContact OD1-CB 3.24Å; D612-S614 WeakPolarHBondContact OD1-CB 3.28Å; D612-S614 PolarHBondContact OD1-N 3.32Å; S614-P616 VanDerWaalsContact C-CD 3.49Å; S614-P616 VanDerWaalsContact C-N 3.32Å; S614-P616 WeakPolarHBondContact OG-CD 3.15Å; S614-R617 WeakPolarHBondContact O-CA 3.44Å; S614-R617 WeakPolarHBondContact O-CB 3.44Å; S614-R617 PolarHBondContact O-N 3.08Å; S614-R617 PolarHBondContact OG-N 3.09Å; S614-L618 WeakPolarHBondContact O-CG 3.4Å; S614-L618 PolarHBondContact O-N 3.16Å
615V94.9Very high96.3Very high68 Ų6852 Ų5241%0.41228%0.282SS..Hα-helixtrans-54.3-42171.8-179.70000112.5V613 R617 L618 K619 M633V613-V615 PolarHBondContact O-N 3.24Å; V615-R617 VanDerWaalsContact C-N 3.28Å; V615-R617 PolarHBondContact O-N 3.43Å; V615-L618 PolarHBondContact O-N 3.24Å; V615-K619 WeakPolarHBondContact O-CG 3.47Å; V615-K619 PolarHBondContact O-N 3.19Å; V615-M633 HydrophobicContact CG2-CE 3.48Å; V615-M633 VanDerWaalsContact CG2-CE 3.48Å; V615-M633 HydrophobicContact CG2-SD 4.42Å
616P95.4Very high96.1Very high89 Ų8957.7 Ų57.758%0.57831%0.308SS*.Hα-helixtrans-56.9-39.9172.8-26.635.5000113.4S614 K619 Q620S614-P616 VanDerWaalsContact C-CD 3.49Å; S614-P616 VanDerWaalsContact C-N 3.32Å; S614-P616 WeakPolarHBondContact OG-CD 3.15Å; P616-K619 PolarHBondContact O-N 3.01Å; P616-Q620 PolarHBondContact O-N 2.94Å; P616-Q620 VanDerWaalsContact O-N 3.14Å
617R93.9Very high95.7Very high49 Ų4959.7 Ų59.719%0.18533%0.329CS..Hα-helixtrans-68.7-42.3177.7-176.155.8179.8166.93.5111.9G590 S614 V615 K619 Q620 L621G590-R617 VanDerWaalsContact O-CZ 3.25Å; G590-R617 PolarHBondContact O-NE 3.2Å; G590-R617 PolarHBondContact O-NH2 2.79Å; S614-R617 WeakPolarHBondContact O-CA 3.44Å; S614-R617 WeakPolarHBondContact O-CB 3.44Å; S614-R617 PolarHBondContact O-N 3.08Å; S614-R617 PolarHBondContact OG-N 3.09Å; V615-R617 VanDerWaalsContact C-N 3.28Å; V615-R617 PolarHBondContact O-N 3.43Å; R617-K619 VanDerWaalsContact C-N 3.3Å; R617-K619 PolarHBondContact O-N 3.07Å; R617-Q620 WeakPolarHBondContact O-CB 3.41Å; R617-Q620 PolarHBondContact O-N 3.16Å; R617-Q620 VanDerWaalsContact O-N 3.14Å; R617-L621 HydrophobicContact CG-CD1 4.16Å; R617-L621 WeakPolarHBondContact O-CG 3.17Å; R617-L621 PolarHBondContact O-N 3.15Å
618L97Very high95.4Very high15 Ų1562.5 Ų62.58%0.07934%0.344CS..Hα-helixtrans-58.8-42174.5-64.6177.8000111.5D612 S614 V615 Q620 L621 D622D612-L618 HydrophobicContact CB-CD2 3.64Å; D612-L618 HydrophobicContact CB-CG 4.08Å; S614-L618 WeakPolarHBondContact O-CG 3.4Å; S614-L618 PolarHBondContact O-N 3.16Å; V615-L618 PolarHBondContact O-N 3.24Å; L618-Q620 VanDerWaalsContact C-N 3.35Å; L618-Q620 PolarHBondContact O-N 3.38Å; L618-L621 PolarHBondContact O-N 3.31Å; L618-D622 WeakPolarHBondContact O-CB 3.18Å; L618-D622 PolarHBondContact O-N 3.1Å
619K95.7Very high95.3Very high141 Ų14162.4 Ų62.461%0.61334%0.344SS*.Hα-helixtrans-60-41.2173.8-73.2178.2177.7-177.80112.9V615 P616 R617 L623V615-K619 WeakPolarHBondContact O-CG 3.47Å; V615-K619 PolarHBondContact O-N 3.19Å; P616-K619 PolarHBondContact O-N 3.01Å; R617-K619 VanDerWaalsContact C-N 3.3Å; R617-K619 PolarHBondContact O-N 3.07Å; K619-L623 WeakPolarHBondContact O-CG 3.42Å; K619-L623 PolarHBondContact O-N 3.13Å
620Q94.7Very high95.3Very high101 Ų10166.5 Ų66.547%0.47236%0.362SS..Hα-helixtrans-63.5-43.7175.8-72.5178.1-8.300111.7P616 R617 L618 L623 I624P616-Q620 PolarHBondContact O-N 2.94Å; P616-Q620 VanDerWaalsContact O-N 3.14Å; R617-Q620 WeakPolarHBondContact O-CB 3.41Å; R617-Q620 PolarHBondContact O-N 3.16Å; R617-Q620 VanDerWaalsContact O-N 3.14Å; L618-Q620 VanDerWaalsContact C-N 3.35Å; L618-Q620 PolarHBondContact O-N 3.38Å; Q620-L623 PolarHBondContact O-N 2.83Å; Q620-I624 WeakPolarHBondContact O-CD1 3.28Å; Q620-I624 VanDerWaalsContact O-CG1 3.22Å; Q620-I624 WeakPolarHBondContact O-CG1 3.2Å; Q620-I624 PolarHBondContact O-N 3.28Å
621L96.6Very high95.2Very high0 Ų068.5 Ų68.50%037%0.374CS..Hα-helixtrans-64.5-44.5179.4-68.4165000111.1M595 I610 R617 L618 L623 I624 F625 T631M595-L621 HydrophobicContact CB-CD2 4.01Å; M595-L621 HydrophobicContact CG-CD2 3.88Å; I610-L621 HydrophobicContact CD1-CD1 3.86Å; I610-L621 HydrophobicContact CD1-CD2 4.32Å; I610-L621 HydrophobicContact CG1-CD1 4.21Å; I610-L621 HydrophobicContact CG2-CD1 4.09Å; R617-L621 HydrophobicContact CG-CD1 4.16Å; R617-L621 WeakPolarHBondContact O-CG 3.17Å; R617-L621 PolarHBondContact O-N 3.15Å; L618-L621 PolarHBondContact O-N 3.31Å; L621-L623 VanDerWaalsContact C-N 3.28Å; L621-L623 PolarHBondContact O-N 3.31Å; L621-I624 PolarHBondContact O-N 2.74Å; L621-I624 VanDerWaalsContact O-N 3.15Å; L621-F625 HydrophobicContact CD2-CE2 4.06Å; L621-F625 VanDerWaalsContact O-CD2 3.24Å; L621-F625 WeakPolarHBondContact O-CD2 3.35Å; L621-F625 PolarHBondContact O-N 3.01Å; L621-T631 HydrophobicContact CB-CG2 4.12Å
622D96.4Very high95.2Very high71 Ų7170.2 Ų70.238%0.3838%0.383SS..Hα-helixtrans-54.5-44.4176.1-169.167.3000112L618 D626 G627 T631L618-D622 WeakPolarHBondContact O-CB 3.18Å; L618-D622 PolarHBondContact O-N 3.1Å; D622-D626 PolarHBondContact O-N 3.46Å; D622-G627 PolarHBondContact O-N 3.48Å; D622-G627 VanDerWaalsContact O-N 3.17Å; D622-T631 HydrophobicContact CB-CG2 4.16Å
623L94.7Very high95.3Very high139 Ų13972.5 Ų72.573%0.72839%0.393SS*.Hα-helixtrans-67.2-43.5175-70.3169.5000113.3K619 Q620 L621 F625 D626K619-L623 WeakPolarHBondContact O-CG 3.42Å; K619-L623 PolarHBondContact O-N 3.13Å; Q620-L623 PolarHBondContact O-N 2.83Å; L621-L623 VanDerWaalsContact C-N 3.28Å; L621-L623 PolarHBondContact O-N 3.31Å; L623-F625 VanDerWaalsContact C-N 3.26Å; L623-F625 PolarHBondContact O-N 3.07Å; L623-D626 PolarHBondContact O-N 3.09Å
624I94.4Very high95.3Very high96 Ų9668.4 Ų68.449%0.49237%0.369SS..Hα-helixtrans-62.3-36.5-179.2-73.8164.5000111.4M595 Q620 L621M595-I624 HydrophobicContact SD-CD1 4.1Å; Q620-I624 WeakPolarHBondContact O-CD1 3.28Å; Q620-I624 VanDerWaalsContact O-CG1 3.22Å; Q620-I624 WeakPolarHBondContact O-CG1 3.2Å; Q620-I624 PolarHBondContact O-N 3.28Å; L621-I624 PolarHBondContact O-N 2.74Å; L621-I624 VanDerWaalsContact O-N 3.15Å
625F96.1Very high95.4Very high22 Ų2269.4 Ų69.410%0.09637%0.371CS..Hα-helixtrans-97.80.1-176.5-70.9-74.2000113.7M595 A598 K599 L621 L623 G627 N628 I629M595-F625 HydrophobicContact CG-CE2 4.27Å; M595-F625 HydrophobicContact CG-CZ 4.38Å; A598-F625 HydrophobicContact CB-CZ 4.23Å; K599-F625 HydrophobicContact CB-CE1 3.91Å; K599-F625 HydrophobicContact CB-CZ 3.95Å; K599-F625 HydrophobicContact CG-CE1 4.38Å; L621-F625 HydrophobicContact CD2-CE2 4.06Å; L621-F625 VanDerWaalsContact O-CD2 3.24Å; L621-F625 WeakPolarHBondContact O-CD2 3.35Å; L621-F625 PolarHBondContact O-N 3.01Å; L623-F625 VanDerWaalsContact C-N 3.26Å; L623-F625 PolarHBondContact O-N 3.07Å; F625-G627 PolarHBondContact O-N 2.91Å; F625-N628 WeakPolarHBondContact O-CB 3.44Å; F625-N628 PolarHBondContact O-N 2.9Å; F625-N628 PolarHBondContact O-ND2 3.28Å; F625-I629 HydrophobicContact CB-CB 4.48Å; F625-I629 HydrophobicContact CB-CD1 4.14Å; F625-I629 HydrophobicContact CB-CG1 3.74Å; F625-I629 HydrophobicContact CB-CG2 4.24Å; F625-I629 HydrophobicContact CD1-CD1 4.34Å; F625-I629 HydrophobicContact CD1-CG2 4.06Å; F625-I629 HydrophobicContact CD2-CD1 3.17Å; F625-I629 HydrophobicContact CD2-CG1 3.79Å; F625-I629 HydrophobicContact CE2-CD1 3.56Å; F625-I629 HydrophobicContact CG-CD1 3.62Å; F625-I629 HydrophobicContact CG-CG1 3.78Å; F625-I629 HydrophobicContact CG-CG2 4.07Å; F625-I629 HydrophobicContact CZ-CD1 4.28Å
626D93.2Very high95.3Very high138 Ų13870.2 Ų70.274%0.73838%0.38SS*.THydrogen-bonded Turntrans50.645.2-179.5-165.334.8000111.9D622 L623 N628D622-D626 PolarHBondContact O-N 3.46Å; L623-D626 PolarHBondContact O-N 3.09Å; D626-N628 PolarHBondContact O-N 2.9Å
627G88.7Confident95.4Very high49 Ų4973.3 Ų73.351%0.50538%0.381SS..THydrogen-bonded Turntrans67.13.4-177.700000116.2D622 F625 I629D622-G627 PolarHBondContact O-N 3.48Å; D622-G627 VanDerWaalsContact O-N 3.17Å; F625-G627 PolarHBondContact O-N 2.91Å; G627-I629 PolarHBondContact O-N 3.45Å
628N92.8Very high95.5Very high130 Ų13072.5 Ų72.570%0.69538%0.381SS*.SBendtrans-70.3-12179.6-70.9-61.9000114F625 D626F625-N628 WeakPolarHBondContact O-CB 3.44Å; F625-N628 PolarHBondContact O-N 2.9Å; F625-N628 PolarHBondContact O-ND2 3.28Å; D626-N628 PolarHBondContact O-N 2.9Å
629I96.3Very high95.6Very high6 Ų672.1 Ų72.13%0.03138%0.379CS..SBendtrans-122.3149.6171.973.4172.2000109.6A598 A602 V608 I610 F625 G627A598-I629 HydrophobicContact CB-CD1 4.1Å; A602-I629 HydrophobicContact CB-CG2 3.96Å; V608-I629 HydrophobicContact CB-CB 4.18Å; V608-I629 HydrophobicContact CB-CG2 3.93Å; V608-I629 HydrophobicContact CG1-CB 4.39Å; V608-I629 HydrophobicContact CG1-CG2 4.26Å; I610-I629 HydrophobicContact CB-CD1 4.27Å; I610-I629 HydrophobicContact CG2-CD1 3.55Å; I610-I629 HydrophobicContact CG2-CG1 4.34Å; F625-I629 HydrophobicContact CB-CB 4.48Å; F625-I629 HydrophobicContact CB-CD1 4.14Å; F625-I629 HydrophobicContact CB-CG1 3.74Å; F625-I629 HydrophobicContact CB-CG2 4.24Å; F625-I629 HydrophobicContact CD1-CD1 4.34Å; F625-I629 HydrophobicContact CD1-CG2 4.06Å; F625-I629 HydrophobicContact CD2-CD1 3.17Å; F625-I629 HydrophobicContact CD2-CG1 3.79Å; F625-I629 HydrophobicContact CE2-CD1 3.56Å; F625-I629 HydrophobicContact CG-CD1 3.62Å; F625-I629 HydrophobicContact CG-CG1 3.78Å; F625-I629 HydrophobicContact CG-CG2 4.07Å; F625-I629 HydrophobicContact CZ-CD1 4.28Å; G627-I629 PolarHBondContact O-N 3.45Å
630Q97.9Very high95.7Very high105 Ų10569.5 Ų69.549%0.49137%0.369SS..EExtended strand (participates in β ladder)trans-80.9128.6172.8-179.3176.7-10.400110.1V608 T609 I610V608-Q630 PolarHBondContact O-N 3.17Å; T609-Q630 CarbonylContact C-O 3.55Å; T609-Q630 WeakPolarHBondContact CA-O 3.5Å; T609-Q630 HydrophobicContact CG2-CB 4.33Å; T609-Q630 HydrophobicContact CG2-CG 4.15Å; T609-Q630 PolarHBondContact OG1-OE1 3.28Å; I610-Q630 PolarHBondContact N-O 2.81Å
631T97.9Very high95.8Very high42 Ų4268 Ų6826%0.25836%0.362SS..EExtended strand (participates in β ladder)trans-97.9136.8167.859.20000109.7I610 L621 D622I610-T631 HydrophobicContact CG2-CG2 3.92Å; I610-T631 WeakPolarHBondContact O-CA 3.44Å; L621-T631 HydrophobicContact CB-CG2 4.12Å; D622-T631 HydrophobicContact CB-CG2 4.16Å
632L97.8Very high95.9Very high35 Ų3569 Ų6918%0.18337%0.368CS..EExtended strand (participates in β ladder)trans-142.9140.3-176.7-173.562.2000111.7T609 I610 M611 D612 S634 N638 V642T609-L632 HydrophobicContact CG2-CB 3.94Å; T609-L632 HydrophobicContact CG2-CD2 4.15Å; I610-L632 PolarHBondContact O-N 3.17Å; M611-L632 VanDerWaalsContact CA-O 3.24Å; M611-L632 WeakPolarHBondContact CA-O 3.46Å; M611-L632 HydrophobicContact CE-CD2 3.88Å; M611-L632 HydrophobicContact CE-CG 4.13Å; M611-L632 HydrophobicContact CG-CB 4.33Å; D612-L632 PolarHBondContact N-O 2.78Å; L632-S634 PolarHBondContact O-N 3.47Å; L632-N638 HydrophobicContact CD2-CB 4.09Å; L632-N638 HydrophobicContact CG-CB 4.26Å; L632-V642 HydrophobicContact CD2-CG1 3.47Å; L632-V642 VanDerWaalsContact CD2-CG1 3.47Å
633M97.9Very high96Very high75 Ų7565.7 Ų65.737%0.36935%0.35SS..EExtended strand (participates in β ladder)trans-64.6129.7176.6-175.463.4110.700110.8V615 N635 N638V615-M633 HydrophobicContact CG2-CE 3.48Å; V615-M633 VanDerWaalsContact CG2-CE 3.48Å; V615-M633 HydrophobicContact CG2-SD 4.42Å; M633-N635 PolarHBondContact O-N 2.93Å; M633-N638 WeakPolarHBondContact O-CB 3.06Å; M633-N638 PolarHBondContact O-ND2 3.47Å
634S96Very high96.1Very high19 Ų1963.5 Ų63.513%0.13334%0.335CS..  trans-8296177.2-166.40000111D612 L632D612-S634 PolarHBondContact O-N 3.42Å; L632-S634 PolarHBondContact O-N 3.47Å
635N94.6Very high96.3Very high67 Ų6762.9 Ų62.936%0.35834%0.335SS..  trans-133.8161.6168.361.757000108.8M633 Y637 N638 I639M633-N635 PolarHBondContact O-N 2.93Å; N635-Y637 PolarHBondContact O-N 2.91Å; N635-Y637 VanDerWaalsContact O-N 3.16Å; N635-Y637 PolarHBondContact OD1-N 3.5Å; N635-N638 PolarHBondContact ND2-ND2 3.4Å; N635-N638 VanDerWaalsContact ND2-ND2 3.14Å; N635-N638 PolarHBondContact O-N 3.28Å; N635-N638 VanDerWaalsContact O-N 3.12Å; N635-N638 WeakPolarHBondContact OD1-CB 3.37Å; N635-N638 PolarHBondContact OD1-N 3.05Å; N635-I639 WeakPolarHBondContact O-CG1 3.41Å; N635-I639 PolarHBondContact O-N 3.25Å
636S93.3Very high96.4Very high86 Ų8661.9 Ų61.960%0.60133%0.331SS*.Hα-helixtrans-54.6-39-173.1-51.10000113.2Q640S636-Q640 WeakPolarHBondContact O-CB 3.16Å; S636-Q640 PolarHBondContact O-N 3.19Å
637Y96.7Very high96.6Very high153 Ų15355.7 Ų55.760%0.630%0.298SS*.Hα-helixtrans-64.6-51.8177.6179.3-91.4000111.7N635 I639 Q640 E641N635-Y637 PolarHBondContact O-N 2.91Å; N635-Y637 VanDerWaalsContact O-N 3.16Å; N635-Y637 PolarHBondContact OD1-N 3.5Å; Y637-I639 VanDerWaalsContact C-N 3.35Å; Y637-I639 PolarHBondContact O-N 3.29Å; Y637-Q640 PolarHBondContact O-N 2.96Å; Y637-E641 HydrophobicContact CD1-CG 4.25Å; Y637-E641 HydrophobicContact CE1-CG 3.79Å; Y637-E641 HydrophobicContact CE2-CG 4.35Å; Y637-E641 WeakPolarHBondContact O-CG 3.27Å; Y637-E641 PolarHBondContact O-N 3.42Å
638N97.8Very high97.1Very high33 Ų3353.4 Ų53.418%0.17627%0.274CS..Hα-helixtrans-63.4-40.5-179.1-75.7-9.9000112M611 L632 M633 N635 E641 V642M611-N638 HydrophobicContact CE-CB 3.61Å; L632-N638 HydrophobicContact CD2-CB 4.09Å; L632-N638 HydrophobicContact CG-CB 4.26Å; M633-N638 WeakPolarHBondContact O-CB 3.06Å; M633-N638 PolarHBondContact O-ND2 3.47Å; N635-N638 PolarHBondContact ND2-ND2 3.4Å; N635-N638 VanDerWaalsContact ND2-ND2 3.14Å; N635-N638 PolarHBondContact O-N 3.28Å; N635-N638 VanDerWaalsContact O-N 3.12Å; N635-N638 WeakPolarHBondContact OD1-CB 3.37Å; N635-N638 PolarHBondContact OD1-N 3.05Å; N638-E641 PolarHBondContact O-N 2.88Å; N638-V642 WeakPolarHBondContact O-CG2 3.37Å; N638-V642 PolarHBondContact O-N 3Å; N638-V642 VanDerWaalsContact O-N 3.1Å
639I97.7Very high97.4Very high6 Ų647.2 Ų47.23%0.03124%0.241CC..Hα-helixtrans-58.8-52.2175.7-68.2171.9000108.8I588 M611 N635 Y637 E641 V642 L643 V664 M668I588-I639 HydrophobicContact CD1-CG2 4.24Å; M611-I639 HydrophobicContact CE-CB 4.45Å; M611-I639 HydrophobicContact CE-CG1 3.78Å; M611-I639 HydrophobicContact SD-CG1 4.04Å; N635-I639 WeakPolarHBondContact O-CG1 3.41Å; N635-I639 PolarHBondContact O-N 3.25Å; Y637-I639 VanDerWaalsContact C-N 3.35Å; Y637-I639 PolarHBondContact O-N 3.29Å; I639-E641 VanDerWaalsContact C-N 3.32Å; I639-E641 PolarHBondContact O-N 3.04Å; I639-V642 WeakPolarHBondContact O-CG2 3.32Å; I639-V642 PolarHBondContact O-N 3.34Å; I639-L643 HydrophobicContact CG2-CD1 3.61Å; I639-L643 HydrophobicContact CG2-CG 4.23Å; I639-L643 WeakPolarHBondContact O-CB 3.29Å; I639-L643 WeakPolarHBondContact O-CG 3.47Å; I639-L643 PolarHBondContact O-N 3.28Å; I639-L643 VanDerWaalsContact O-N 3.12Å; I639-V664 HydrophobicContact CG2-CG2 4.16Å; I639-M668 HydrophobicContact CG2-SD 3.79Å
640Q97.4Very high97.5Very high87 Ų8746.9 Ų46.941%0.40724%0.239SC..Hα-helixtrans-58.9-41-179.5-174.3174.77.400112.8S636 Y637 K644 M668S636-Q640 WeakPolarHBondContact O-CB 3.16Å; S636-Q640 PolarHBondContact O-N 3.19Å; Y637-Q640 PolarHBondContact O-N 2.96Å; Q640-K644 WeakPolarHBondContact O-CG 3.45Å; Q640-M668 HydrophobicContact CB-CE 4.09Å; Q640-M668 HydrophobicContact CB-CG 4.33Å; Q640-M668 HydrophobicContact CB-SD 4.37Å; Q640-M668 HydrophobicContact CG-CG 4.34Å
641E98.1Very high97.5Very high70 Ų7041.9 Ų41.933%0.32722%0.216SC..Hα-helixtrans-68.2-45.2-179.7-71.9-50.8126.500113Y637 N638 I639 L643 K644Y637-E641 HydrophobicContact CD1-CG 4.25Å; Y637-E641 HydrophobicContact CE1-CG 3.79Å; Y637-E641 HydrophobicContact CE2-CG 4.35Å; Y637-E641 WeakPolarHBondContact O-CG 3.27Å; Y637-E641 PolarHBondContact O-N 3.42Å; N638-E641 PolarHBondContact O-N 2.88Å; I639-E641 VanDerWaalsContact C-N 3.32Å; I639-E641 PolarHBondContact O-N 3.04Å; E641-L643 VanDerWaalsContact C-N 3.33Å; E641-L643 PolarHBondContact O-N 3.28Å; E641-K644 PolarHBondContact O-N 3.36Å; E641-K644 IonicContact OE1-NZ 2.79Å; E641-K644 PolarHBondContact OE1-NZ 3Å; E641-K644 IonicContact OE2-NZ 2.67Å; E641-K644 PolarHBondContact OE2-NZ 2.9Å
642V97.8Very high97.4Very high20 Ų2040.4 Ų40.412%0.12121%0.208CC..Hα-helixtrans-71.7-28.5-178.2-60.20000112.8V586 T609 M611 L632 N638 I639 K644 T645 A646V586-V642 HydrophobicContact CG1-CG2 3.74Å; V586-V642 HydrophobicContact CG2-CB 4.03Å; V586-V642 HydrophobicContact CG2-CG2 3.98Å; T609-V642 HydrophobicContact CG2-CG1 4.42Å; M611-V642 HydrophobicContact CE-CG2 4.3Å; M611-V642 HydrophobicContact SD-CG2 3.63Å; L632-V642 HydrophobicContact CD2-CG1 3.47Å; L632-V642 VanDerWaalsContact CD2-CG1 3.47Å; N638-V642 WeakPolarHBondContact O-CG2 3.37Å; N638-V642 PolarHBondContact O-N 3Å; N638-V642 VanDerWaalsContact O-N 3.1Å; I639-V642 WeakPolarHBondContact O-CG2 3.32Å; I639-V642 PolarHBondContact O-N 3.34Å; V642-K644 VanDerWaalsContact C-N 3.26Å; V642-K644 PolarHBondContact O-N 2.95Å; V642-T645 PolarHBondContact O-N 2.61Å; V642-T645 PolarHBondContact O-OG1 3.12Å; V642-A646 PolarHBondContact O-N 3.22Å
643L98.1Very high97.2Very high1 Ų140.1 Ų40.11%0.00521%0.208CC..Hα-helixtrans-66.2-27178.6-72.5177.6000112.9I639 E641 T645 A646 V649 V664 M668 M672 P673I639-L643 HydrophobicContact CG2-CD1 3.61Å; I639-L643 HydrophobicContact CG2-CG 4.23Å; I639-L643 WeakPolarHBondContact O-CB 3.29Å; I639-L643 WeakPolarHBondContact O-CG 3.47Å; I639-L643 PolarHBondContact O-N 3.28Å; I639-L643 VanDerWaalsContact O-N 3.12Å; E641-L643 VanDerWaalsContact C-N 3.33Å; E641-L643 PolarHBondContact O-N 3.28Å; L643-T645 PolarHBondContact O-N 3.27Å; L643-T645 VanDerWaalsContact O-N 3.14Å; L643-A646 PolarHBondContact O-N 3.5Å; L643-V649 HydrophobicContact CD2-CB 4.21Å; L643-V649 HydrophobicContact CD2-CG1 3.7Å; L643-V649 HydrophobicContact CD2-CG2 3.41Å; L643-V649 VanDerWaalsContact CD2-CG2 3.41Å; L643-V664 HydrophobicContact CD1-CG1 3.61Å; L643-V664 HydrophobicContact CD1-CG2 4.37Å; L643-M668 HydrophobicContact CD1-CB 3.97Å; L643-M668 HydrophobicContact CD1-SD 4.46Å; L643-M672 HydrophobicContact CB-CG 4.11Å; L643-M672 HydrophobicContact CD2-SD 4.29Å; L643-P673 WeakPolarHBondContact O-CD 3.23Å
644K98Very high96.7Very high94 Ų9439.9 Ų39.941%0.40921%0.207SC..THydrogen-bonded Turntrans-61.1-23.4178.4-66.9173.4-169.7171.20113.6Q640 E641 V642 P673Q640-K644 WeakPolarHBondContact O-CG 3.45Å; E641-K644 PolarHBondContact O-N 3.36Å; E641-K644 IonicContact OE1-NZ 2.79Å; E641-K644 PolarHBondContact OE1-NZ 3Å; E641-K644 IonicContact OE2-NZ 2.67Å; E641-K644 PolarHBondContact OE2-NZ 2.9Å; V642-K644 VanDerWaalsContact C-N 3.26Å; V642-K644 PolarHBondContact O-N 2.95Å; K644-P673 WeakPolarHBondContact O-CG 3.39Å
645T97.2Very high96.2Very high83 Ų8342.4 Ų42.451%0.50922%0.218SC..THydrogen-bonded Turntrans-1170.3-177.459.60000113.3N584 V642 L643 D647N584-T645 WeakPolarHBondContact CB-O 3.39Å; N584-T645 PolarHBondContact ND2-O 2.9Å; V642-T645 PolarHBondContact O-N 2.61Å; V642-T645 PolarHBondContact O-OG1 3.12Å; L643-T645 PolarHBondContact O-N 3.27Å; L643-T645 VanDerWaalsContact O-N 3.14Å; T645-D647 PolarHBondContact O-N 3.01Å
646A98.4Very high95.5Very high0 Ų042.3 Ų42.30%022%0.222CC..  trans-74.4124.1-176.100000111.8V586 V642 L643 V649 P673 S676V586-A646 HydrophobicContact CB-CB 4.29Å; V586-A646 HydrophobicContact CG2-CB 3.72Å; V642-A646 PolarHBondContact O-N 3.22Å; L643-A646 PolarHBondContact O-N 3.5Å; A646-V649 HydrophobicContact CB-CG2 3.54Å; A646-P673 WeakPolarHBondContact O-CD 2.99Å; A646-P673 WeakPolarHBondContact O-CG 3.36Å; A646-S676 WeakPolarHBondContact O-CB 2.81Å
647D98.5Very high94.6Very high9 Ų938.7 Ų38.75%0.04820%0.198CC..SBendtrans-82.1-37169.5-61.8-59000110.4L563 R570 V572 G583 N584 T645 S676 V677L563-D647 HydrophobicContact CD1-CB 4.33Å; L563-D647 HydrophobicContact CD2-CB 4.05Å; L563-D647 WeakPolarHBondContact CD2-O 3.38Å; R570-D647 WeakPolarHBondContact CD-OD1 3.31Å; R570-D647 IonicContact CZ-OD1 2.68Å; R570-D647 IonicContact NE-OD1 2.68Å; R570-D647 IonicContact NH1-OD1 2.82Å; R570-D647 PolarHBondContact NH1-OD1 3.39Å; V572-D647 HydrophobicContact CG1-CB 4.48Å; G583-D647 WeakPolarHBondContact CA-OD2 3.43Å; N584-D647 PolarHBondContact N-OD2 3.2Å; N584-D647 PolarHBondContact O-N 2.98Å; T645-D647 PolarHBondContact O-N 3.01Å; D647-S676 WeakPolarHBondContact O-CA 3.23Å; D647-S676 WeakPolarHBondContact O-CB 3.29Å; D647-V677 PolarHBondContact O-N 3.1Å
648L98.7Very high94.1Very high0 Ų034.4 Ų34.40%018%0.183CC..EExtended strand (participates in β ladder)trans-131.2133.5175.9169.363.5000110.3L563 L574 N584 V585 V586 I650 V677 V679L563-L648 HydrophobicContact CD1-CB 3.92Å; L574-L648 HydrophobicContact CD1-CD2 4.5Å; N584-L648 PolarHBondContact O-N 3.05Å; V585-L648 CarbonylContact C-O 3.54Å; V585-L648 WeakPolarHBondContact CA-O 3.44Å; V585-L648 HydrophobicContact CG1-CD2 4.17Å; V585-L648 HydrophobicContact CG1-CG 4.28Å; V585-L648 HydrophobicContact CG2-CB 4.23Å; V585-L648 HydrophobicContact CG2-CD2 4.16Å; V586-L648 PolarHBondContact N-O 3.14Å; L648-I650 HydrophobicContact CD1-CG1 4.24Å; L648-I650 HydrophobicContact CD2-CD1 4.19Å; L648-I650 HydrophobicContact CD2-CG1 4.4Å; L648-I650 HydrophobicContact CG-CD1 4.46Å; L648-I650 HydrophobicContact CG-CG1 4.15Å; L648-V677 CarbonylContact C-O 3.39Å; L648-V677 WeakPolarHBondContact CA-O 3.5Å; L648-V677 HydrophobicContact CD1-CB 3.98Å; L648-V677 HydrophobicContact CD1-CG1 3.91Å; L648-V679 HydrophobicContact CD1-CG2 3.85Å
649V98.7Very high93.5Very high0 Ų040.2 Ų40.20%020%0.202CC..EExtended strand (participates in β ladder)trans-121.5131174.1-173.10000109.3V586 I588 L643 A646 M672 V677 I678 V679 F689V586-V649 HydrophobicContact CB-CG2 4.46Å; V586-V649 CarbonylContact O-C 3.43Å; V586-V649 VanDerWaalsContact O-CA 3.32Å; V586-V649 WeakPolarHBondContact O-CA 3.49Å; I588-V649 HydrophobicContact CD1-CG1 4.14Å; I588-V649 HydrophobicContact CG1-CG1 4.48Å; L643-V649 HydrophobicContact CD2-CB 4.21Å; L643-V649 HydrophobicContact CD2-CG1 3.7Å; L643-V649 HydrophobicContact CD2-CG2 3.41Å; L643-V649 VanDerWaalsContact CD2-CG2 3.41Å; A646-V649 HydrophobicContact CB-CG2 3.54Å; V649-M672 HydrophobicContact CB-CE 4.3Å; V649-M672 HydrophobicContact CG2-CE 3.39Å; V649-M672 HydrophobicContact CG2-SD 4.3Å; V649-V677 PolarHBondContact N-O 3.43Å; V649-I678 HydrophobicContact CB-CG1 4.21Å; V649-I678 CarbonylContact O-C 3.49Å; V649-I678 WeakPolarHBondContact O-CA 3.37Å; V649-V679 PolarHBondContact O-N 3.19Å; V649-F689 HydrophobicContact CG1-CE1 3.84Å; V649-F689 HydrophobicContact CG1-CZ 3.84Å
650I98.6Very high92.9Very high0 Ų040.2 Ų40.20%020%0.203CC..EExtended strand (participates in β ladder)trans-117.1115.7178.5-59.4173.8000108.6A555 A556 V585 V586 V587 I588 A597 L648 V679 V681A555-I650 HydrophobicContact CB-CD1 3.97Å; A555-I650 HydrophobicContact CB-CG1 4.32Å; A555-I650 HydrophobicContact CB-CG2 3.8Å; A556-I650 HydrophobicContact CB-CD1 4.45Å; V585-I650 HydrophobicContact CG1-CD1 4.33Å; V586-I650 PolarHBondContact O-N 3.14Å; V587-I650 HydrophobicContact CG2-CB 4.43Å; I588-I650 PolarHBondContact N-O 2.81Å; A597-I650 HydrophobicContact CB-CD1 3.83Å; A597-I650 HydrophobicContact CB-CG2 4.16Å; L648-I650 HydrophobicContact CD1-CG1 4.24Å; L648-I650 HydrophobicContact CD2-CD1 4.19Å; L648-I650 HydrophobicContact CD2-CG1 4.4Å; L648-I650 HydrophobicContact CG-CD1 4.46Å; L648-I650 HydrophobicContact CG-CG1 4.15Å; I650-V679 WeakPolarHBondContact CA-O 3.09Å; I650-V679 HydrophobicContact CG1-CB 4.38Å; I650-V681 HydrophobicContact CG2-CG2 3.88Å
651G97.9Very high92.6Very high0 Ų037.8 Ų37.80%020%0.195CC..EExtended strand (participates in β ladder)trans-86.6114.9174.300000111.3V679 V681G651-V679 PolarHBondContact N-O 2.69Å; G651-V681 VanDerWaalsContact O-CB 3.27Å; G651-V681 WeakPolarHBondContact O-CB 3.5Å; G651-V681 PolarHBondContact O-N 3.3Å
652A96.5Very high92.3Very high10 Ų1038.9 Ų38.98%0.08321%0.207CC..  trans-13322.1-168.800000113V587 I588 V593V587-A652 HydrophobicContact CG1-CB 4.41Å; I588-A652 CarbonylContact O-C 3.43Å; I588-A652 WeakPolarHBondContact O-CA 3.44Å; I588-A652 WeakPolarHBondContact O-CB 3.13Å; I588-A652 PolarHBondContact O-N 3.02Å; V593-A652 HydrophobicContact CB-CB 3.92Å; V593-A652 HydrophobicContact CG1-CB 3.56Å
653V93.4Very high92.2Very high30 Ų3040.8 Ų40.818%0.18222%0.216CC..  trans-89.3127178.6-178.30000110.3I588 P661 L663 A682 I688I588-V653 HydrophobicContact CG2-CG2 4.03Å; I588-V653 WeakPolarHBondContact O-CG2 3.29Å; I588-V653 PolarHBondContact O-N 3.39Å; V653-P661 HydrophobicContact CG1-CG 4.07Å; V653-L663 HydrophobicContact CB-CD1 4.07Å; V653-L663 HydrophobicContact CG1-CD1 4.17Å; V653-L663 HydrophobicContact CG2-CD1 3.65Å; V653-A682 VanDerWaalsContact O-CB 3.31Å; V653-A682 WeakPolarHBondContact O-CB 3.34Å; V653-I688 HydrophobicContact CB-CG2 4.06Å
654L87.3Confident92.2Very high69 Ų6940.8 Ų40.836%0.36122%0.216SC..  trans-130.3134.7174.3174.773.7000108.3L541 L544 Q685L541-L654 HydrophobicContact CD1-CD2 4.46Å; L544-L654 HydrophobicContact CD2-CD2 3.4Å; L654-Q685 HydrophobicContact CD1-CG 3.81Å
655I85.2Confident92.1Very high72 Ų7237.8 Ų37.837%0.36921%0.207SC..  trans-110.4114.5167.1-56.8178.1000106.6G657 H658 P661I655-G657 PolarHBondContact O-N 2.94Å; I655-H658 HydrophobicContact CB-CB 4.06Å; I655-H658 HydrophobicContact CG2-CB 3.93Å; I655-H658 PolarHBondContact O-N 3.46Å; I655-H658 VanDerWaalsContact O-N 3.08Å; I655-P661 HydrophobicContact CD1-CG 3.99Å
656P80.3Confident92.1Very high66 Ų6638.1 Ų38.143%0.42920%0.201SC..THydrogen-bonded Turntrans-54.1126.8-175.9-27.235.1000112.5L541 H658L541-P656 HydrophobicContact CD1-CB 4.25Å; L541-P656 HydrophobicContact CD1-CG 4.03Å; P656-H658 PolarHBondContact O-N 2.98Å
657G74.1Confident92Very high9 Ų944.1 Ų44.19%0.09323%0.229CC..THydrogen-bonded Turntrans79.2-7.1178.800000116I655 A769I655-G657 PolarHBondContact O-N 2.94Å; G657-A769 WeakPolarHBondContact O-CB 3.38Å
658H85.4Confident91.9Very high63 Ų6344.7 Ų44.729%0.29223%0.232SC..SBendtrans-111.9159.3-179.9-73-80.9000112.2I655 P656 A769 D773I655-H658 HydrophobicContact CB-CB 4.06Å; I655-H658 HydrophobicContact CG2-CB 3.93Å; I655-H658 PolarHBondContact O-N 3.46Å; I655-H658 VanDerWaalsContact O-N 3.08Å; P656-H658 PolarHBondContact O-N 2.98Å; H658-A769 VanDerWaalsContact CE1-CB 3.42Å; H658-A769 WeakPolarHBondContact CE1-CB 3.5Å; H658-A769 WeakPolarHBondContact NE2-CB 3.35Å; H658-D773 VanDerWaalsContact CA-OD2 3.28Å; H658-D773 WeakPolarHBondContact CA-OD2 3.38Å; H658-D773 IonicContact ND1-OD1 2.73Å; H658-D773 IonicContact ND1-OD2 3.83Å
659R85.2Confident91.9Very high155 Ų15544.7 Ų44.759%0.58523%0.232SC*.PPolyproline II helixtrans-58.4142.8163.2-165.4-178.7176.5174.3-1.2110.6Q685 D773R659-Q685 WeakPolarHBondContact CG-O 3.38Å; R659-D773 PolarHBondContact N-OD2 3.28Å
660A86.6Confident91.8Very high6 Ų647.7 Ų47.75%0.0525%0.253CS..PPolyproline II helixtrans-59.7136.4174.800000110.8A682 Q685 I688A660-A682 HydrophobicContact CB-CB 4.2Å; A660-Q685 HydrophobicContact CB-CB 4.11Å; A660-Q685 WeakPolarHBondContact CB-O 3.31Å; A660-Q685 PolarHBondContact N-O 3.24Å; A660-I688 HydrophobicContact CB-CG2 4.41Å
661P90.3Very high91.7Very high37 Ų3749.8 Ų49.824%0.2427%0.274CS..PPolyproline II helixtrans-75.2139.6176.830.8-34.2000110.5V653 I655 L663 I688V653-P661 HydrophobicContact CG1-CG 4.07Å; I655-P661 HydrophobicContact CD1-CG 3.99Å; P661-L663 HydrophobicContact CB-CD2 4.11Å; P661-L663 HydrophobicContact CB-CG 4.35Å; P661-L663 HydrophobicContact CG-CD1 4.32Å; P661-L663 HydrophobicContact CG-CD2 4.13Å; P661-L663 HydrophobicContact CG-CG 4.09Å; P661-L663 PolarHBondContact O-N 2.8Å; P661-I688 WeakPolarHBondContact O-CA 3.29Å
662T92.7Very high91.7Very high92 Ų9250.4 Ų50.456%0.56428%0.278SS*.  trans-74.2110.4167.9-51.20000109.3E690T662-E690 HydrophobicContact CG2-CB 3.82Å
663L95.1Very high91.8Very high61 Ų6150.8 Ų50.832%0.31928%0.279SS..  trans-108.8-25.3-176.1-62.9179.2000113.3I588 V653 P661 I688I588-L663 HydrophobicContact CG2-CD1 4.27Å; V653-L663 HydrophobicContact CB-CD1 4.07Å; V653-L663 HydrophobicContact CG1-CD1 4.17Å; V653-L663 HydrophobicContact CG2-CD1 3.65Å; P661-L663 HydrophobicContact CB-CD2 4.11Å; P661-L663 HydrophobicContact CB-CG 4.35Å; P661-L663 HydrophobicContact CG-CD1 4.32Å; P661-L663 HydrophobicContact CG-CD2 4.13Å; P661-L663 HydrophobicContact CG-CG 4.09Å; P661-L663 PolarHBondContact O-N 2.8Å; L663-I688 PolarHBondContact N-O 3.47Å
664V97.2Very high91.9Very high0 Ų055.1 Ų55.10%030%0.295CS..BIsolated β-bridgetrans-114111.6-177.7-173.60000108.7I588 I639 L643 M668 V669 I688 F689 E690I588-V664 HydrophobicContact CD1-CG2 3.63Å; I639-V664 HydrophobicContact CG2-CG2 4.16Å; L643-V664 HydrophobicContact CD1-CG1 3.61Å; L643-V664 HydrophobicContact CD1-CG2 4.37Å; V664-M668 HydrophobicContact CG1-CB 3.76Å; V664-M668 HydrophobicContact CG1-SD 4.32Å; V664-V669 HydrophobicContact CG1-CG2 3.74Å; V664-I688 PolarHBondContact N-O 3.43Å; V664-I688 VanDerWaalsContact N-O 3.1Å; V664-F689 HydrophobicContact CB-CD1 3.53Å; V664-F689 HydrophobicContact CB-CE1 4.07Å; V664-F689 HydrophobicContact CB-CG 4.32Å; V664-F689 HydrophobicContact CG1-CD1 3.77Å; V664-F689 HydrophobicContact CG1-CE1 4.26Å; V664-F689 HydrophobicContact CG2-CD1 3.75Å; V664-F689 HydrophobicContact CG2-CE1 3.77Å; V664-E690 PolarHBondContact O-N 2.87Å
665S96.7Very high92.4Very high31 Ų3153.2 Ų53.222%0.21729%0.285CS..  trans-75.7163-179.684.10000112E667 M668 V669 E690S665-E667 VanDerWaalsContact CB-OE2 3.29Å; S665-E667 WeakPolarHBondContact CB-OE2 3.07Å; S665-E667 PolarHBondContact O-N 3.2Å; S665-E667 PolarHBondContact OG-N 3.37Å; S665-E667 PolarHBondContact OG-OE2 3.46Å; S665-M668 WeakPolarHBondContact O-CB 3.48Å; S665-M668 PolarHBondContact O-N 3.1Å; S665-M668 VanDerWaalsContact O-N 3.08Å; S665-M668 PolarHBondContact OG-N 3.44Å; S665-V669 PolarHBondContact O-N 2.84Å; S665-V669 VanDerWaalsContact O-N 3.13Å; S665-E690 WeakPolarHBondContact CA-OE2 3.29Å
666K96.6Very high93Very high90 Ų9049.8 Ų49.839%0.39127%0.267SS..Hα-helixtrans-54.4-39.1173.7-173.5-173-179.9-171.40112.7M668 V669 S670 E690 T691 E706K666-M668 VanDerWaalsContact C-N 3.34Å; K666-V669 PolarHBondContact O-N 2.73Å; K666-S670 WeakPolarHBondContact O-CB 3.12Å; K666-S670 PolarHBondContact O-N 3.29Å; K666-S670 PolarHBondContact O-OG 3.02Å; K666-E690 PolarHBondContact N-OE2 2.84Å; K666-T691 HydrophobicContact CB-CG2 4.32Å; K666-T691 HydrophobicContact CG-CG2 4.08Å; K666-E706 WeakPolarHBondContact CE-OE1 3.27Å; K666-E706 HydrophobicContact CG-CG 4.32Å; K666-E706 IonicContact NZ-OE1 2.6Å
667E96.5Very high93.9Very high126 Ų12646.6 Ų46.659%0.58925%0.247SC*.Hα-helixtrans-64.7-39.2177.9-61.971.3-152.600111.6S665 S670 G671S665-E667 VanDerWaalsContact CB-OE2 3.29Å; S665-E667 WeakPolarHBondContact CB-OE2 3.07Å; S665-E667 PolarHBondContact O-N 3.2Å; S665-E667 PolarHBondContact OG-N 3.37Å; S665-E667 PolarHBondContact OG-OE2 3.46Å; E667-S670 PolarHBondContact O-N 3.47Å; E667-G671 PolarHBondContact O-N 2.85Å
668M97.8Very high95Very high22 Ų2246.2 Ų46.211%0.10824%0.242CC..Hα-helixtrans-63.8-43.3175.8-65-173.9-179.300111.2I639 Q640 L643 V664 S665 K666 S670 G671I639-M668 HydrophobicContact CG2-SD 3.79Å; Q640-M668 HydrophobicContact CB-CE 4.09Å; Q640-M668 HydrophobicContact CB-CG 4.33Å; Q640-M668 HydrophobicContact CB-SD 4.37Å; Q640-M668 HydrophobicContact CG-CG 4.34Å; L643-M668 HydrophobicContact CD1-CB 3.97Å; L643-M668 HydrophobicContact CD1-SD 4.46Å; V664-M668 HydrophobicContact CG1-CB 3.76Å; V664-M668 HydrophobicContact CG1-SD 4.32Å; S665-M668 WeakPolarHBondContact O-CB 3.48Å; S665-M668 PolarHBondContact O-N 3.1Å; S665-M668 VanDerWaalsContact O-N 3.08Å; S665-M668 PolarHBondContact OG-N 3.44Å; K666-M668 VanDerWaalsContact C-N 3.34Å; M668-S670 VanDerWaalsContact C-N 3.34Å; M668-G671 PolarHBondContact O-N 3.37Å
669V97.6Very high95.7Very high0 Ų043.2 Ų43.20%023%0.228CC..Hα-helixtrans-65.7-38.7177.6-178.70000111.5V664 S665 K666 G671 M672 I678 T691 E706 V708V664-V669 HydrophobicContact CG1-CG2 3.74Å; S665-V669 PolarHBondContact O-N 2.84Å; S665-V669 VanDerWaalsContact O-N 3.13Å; K666-V669 PolarHBondContact O-N 2.73Å; V669-G671 PolarHBondContact O-N 3.28Å; V669-M672 HydrophobicContact CB-SD 4.45Å; V669-M672 HydrophobicContact CG1-SD 4.24Å; V669-M672 HydrophobicContact CG2-SD 4.49Å; V669-M672 VanDerWaalsContact O-CB 3.27Å; V669-M672 WeakPolarHBondContact O-CB 3.42Å; V669-M672 WeakPolarHBondContact O-CG 3.41Å; V669-M672 PolarHBondContact O-N 3.18Å; V669-I678 HydrophobicContact CG1-CD1 3.91Å; V669-I678 HydrophobicContact CG2-CD1 4.05Å; V669-T691 HydrophobicContact CB-CG2 3.91Å; V669-T691 HydrophobicContact CG1-CG2 4.02Å; V669-T691 HydrophobicContact CG2-CG2 4.03Å; V669-T691 WeakPolarHBondContact CG2-OG1 3.28Å; V669-E706 HydrophobicContact CG1-CB 4.17Å; V669-V708 HydrophobicContact CG1-CB 4.15Å; V669-V708 HydrophobicContact CG1-CG2 3.93Å
670S96.5Very high96.2Very high62 Ų6235.8 Ų35.843%0.43420%0.2SC..Hα-helixtrans-64.1-23.6176.4-54.60000113.1K666 E667 M668K666-S670 WeakPolarHBondContact O-CB 3.12Å; K666-S670 PolarHBondContact O-N 3.29Å; K666-S670 PolarHBondContact O-OG 3.02Å; E667-S670 PolarHBondContact O-N 3.47Å; M668-S670 VanDerWaalsContact C-N 3.34Å
671G96.5Very high96.7Very high44 Ų4436.3 Ų36.345%0.45420%0.203SC..THydrogen-bonded Turntrans-84.9-3.7175.100000114.6E667 M668 V669E667-G671 PolarHBondContact O-N 2.85Å; M668-G671 PolarHBondContact O-N 3.37Å; V669-G671 PolarHBondContact O-N 3.28Å
672M98.2Very high96.7Very high14 Ų1434.9 Ų34.97%0.06919%0.194CC..SBendtrans-74157178.4-67.5177.95600111.6L643 V649 V669 S676 I678 V708L643-M672 HydrophobicContact CB-CG 4.11Å; L643-M672 HydrophobicContact CD2-SD 4.29Å; V649-M672 HydrophobicContact CB-CE 4.3Å; V649-M672 HydrophobicContact CG2-CE 3.39Å; V649-M672 HydrophobicContact CG2-SD 4.3Å; V669-M672 HydrophobicContact CB-SD 4.45Å; V669-M672 HydrophobicContact CG1-SD 4.24Å; V669-M672 HydrophobicContact CG2-SD 4.49Å; V669-M672 VanDerWaalsContact O-CB 3.27Å; V669-M672 WeakPolarHBondContact O-CB 3.42Å; V669-M672 WeakPolarHBondContact O-CG 3.41Å; V669-M672 PolarHBondContact O-N 3.18Å; M672-S676 WeakPolarHBondContact CE-OG 3.49Å; M672-I678 HydrophobicContact CE-CD1 4.17Å; M672-I678 HydrophobicContact CE-CG1 3.85Å; M672-I678 HydrophobicContact SD-CD1 3.85Å; M672-I678 HydrophobicContact SD-CG1 4.18Å; M672-V708 HydrophobicContact CB-CG2 4Å; M672-V708 HydrophobicContact CE-CG1 4.07Å; M672-V708 HydrophobicContact SD-CG2 4.49Å
673P97.7Very high96.6Very high17 Ų1731 Ų3111%0.1117%0.17CC..PPolyproline II helixtrans-58.3142.6174.3-22.632.4000113R570 L643 K644 A646 H675 S676R570-P673 VanDerWaalsContact CZ-CB 3.45Å; L643-P673 WeakPolarHBondContact O-CD 3.23Å; K644-P673 WeakPolarHBondContact O-CG 3.39Å; A646-P673 WeakPolarHBondContact O-CD 2.99Å; A646-P673 WeakPolarHBondContact O-CG 3.36Å; P673-H675 PolarHBondContact O-N 2.83Å; P673-S676 VanDerWaalsContact O-CB 3.24Å; P673-S676 WeakPolarHBondContact O-CB 3.25Å; P673-S676 PolarHBondContact O-N 2.96Å; P673-S676 PolarHBondContact O-OG 3.07Å
674F96.7Very high96Very high121 Ų12130.3 Ų30.353%0.53117%0.166SC..THydrogen-bonded Turntrans-55.6130.2177.8-172.1-99.7000111.6S676 N707F674-S676 PolarHBondContact O-N 2.84Å; F674-N707 HydrophobicContact CD2-CB 3.47Å; F674-N707 VanDerWaalsContact CD2-CB 3.47Å; F674-N707 HydrophobicContact CE2-CB 3.58Å; F674-N707 HydrophobicContact CG-CB 4.48Å
675H97.1Very high95.3Very high29 Ų2930.7 Ų30.713%0.13417%0.168CC..THydrogen-bonded Turntrans6120.3-175.9-60.3176000115.8R565 G569 R570 P673 N707R565-H675 PolarHBondContact NH1-CE1 3.35Å; R565-H675 VanDerWaalsContact NH1-CE1 3.27Å; R565-H675 PolarHBondContact NH1-ND1 2.98Å; G569-H675 CarbonylContact C-O 3.53Å; G569-H675 WeakPolarHBondContact CA-O 3.32Å; R570-H675 HydrophobicContact CB-CB 4.3Å; R570-H675 WeakPolarHBondContact CB-O 3.32Å; R570-H675 PolarHBondContact N-O 3.22Å; P673-H675 PolarHBondContact O-N 2.83Å; H675-N707 WeakPolarHBondContact CA-O 3.35Å; H675-N707 PolarHBondContact N-O 2.88Å
676S98.3Very high94.6Very high0 Ų030.4 Ų30.40%017%0.17CC..  trans-61.1167.1163.1540000111.2A646 D647 M672 P673 F674 V708 V709A646-S676 WeakPolarHBondContact O-CB 2.81Å; D647-S676 WeakPolarHBondContact O-CA 3.23Å; D647-S676 WeakPolarHBondContact O-CB 3.29Å; M672-S676 WeakPolarHBondContact CE-OG 3.49Å; P673-S676 VanDerWaalsContact O-CB 3.24Å; P673-S676 WeakPolarHBondContact O-CB 3.25Å; P673-S676 PolarHBondContact O-N 2.96Å; P673-S676 PolarHBondContact O-OG 3.07Å; F674-S676 PolarHBondContact O-N 2.84Å; S676-V708 WeakPolarHBondContact O-CG1 3.49Å; S676-V709 PolarHBondContact O-N 3.33Å
677V98.6Very high94.3Very high0 Ų026.1 Ų26.10%015%0.152CC..EExtended strand (participates in β ladder)trans-118.2134.6-175.3-178.90000110.4F562 L563 D647 L648 V649 V679 V709F562-V677 HydrophobicContact CB-CG1 4.11Å; F562-V677 HydrophobicContact CB-CG2 4.13Å; L563-V677 HydrophobicContact CB-CG2 4.49Å; L563-V677 HydrophobicContact CD2-CG2 4.03Å; L563-V677 HydrophobicContact CG-CB 4.48Å; L563-V677 HydrophobicContact CG-CG2 3.87Å; D647-V677 PolarHBondContact O-N 3.1Å; L648-V677 CarbonylContact C-O 3.39Å; L648-V677 WeakPolarHBondContact CA-O 3.5Å; L648-V677 HydrophobicContact CD1-CB 3.98Å; L648-V677 HydrophobicContact CD1-CG1 3.91Å; V649-V677 PolarHBondContact N-O 3.43Å; V677-V679 HydrophobicContact CG1-CG2 4.18Å; V677-V709 CarbonylContact C-O 3.57Å; V677-V709 WeakPolarHBondContact CA-O 3.41Å; V677-V709 HydrophobicContact CG2-CB 4.21Å
678I98.5Very high94.2Very high0 Ų020.1 Ų20.10%012%0.124CC..EExtended strand (participates in β ladder)trans-109130166.1-72.8169.1000108.5V649 V669 M672 F689 V708 V709 Y711V649-I678 HydrophobicContact CB-CG1 4.21Å; V649-I678 CarbonylContact O-C 3.49Å; V649-I678 WeakPolarHBondContact O-CA 3.37Å; V669-I678 HydrophobicContact CG1-CD1 3.91Å; V669-I678 HydrophobicContact CG2-CD1 4.05Å; M672-I678 HydrophobicContact CE-CD1 4.17Å; M672-I678 HydrophobicContact CE-CG1 3.85Å; M672-I678 HydrophobicContact SD-CD1 3.85Å; M672-I678 HydrophobicContact SD-CG1 4.18Å; I678-F689 HydrophobicContact CD1-CD1 3.86Å; I678-F689 HydrophobicContact CD1-CE1 4.06Å; I678-F689 HydrophobicContact CD1-CG 4.44Å; I678-F689 HydrophobicContact CG1-CD1 4.41Å; I678-F689 HydrophobicContact CG1-CE1 4.15Å; I678-F689 HydrophobicContact CG2-CD1 4.04Å; I678-F689 HydrophobicContact CG2-CD2 3.62Å; I678-F689 HydrophobicContact CG2-CE1 3.86Å; I678-F689 HydrophobicContact CG2-CE2 3.41Å; I678-F689 VanDerWaalsContact CG2-CE2 3.41Å; I678-F689 HydrophobicContact CG2-CG 3.96Å; I678-F689 HydrophobicContact CG2-CZ 3.56Å; I678-V708 HydrophobicContact CB-CG1 4.36Å; I678-V708 HydrophobicContact CD1-CG1 3.73Å; I678-V708 HydrophobicContact CG1-CG1 3.76Å; I678-V709 PolarHBondContact N-O 3.13Å; I678-Y711 PolarHBondContact O-N 2.81Å
679V98.3Very high94.2Very high0 Ų019.3 Ų19.30%012%0.119CC..EExtended strand (participates in β ladder)trans-114.2105.1167.3-178.50000107.9A555 L648 V649 I650 G651 V677 V681 Y711 M716A555-V679 HydrophobicContact CB-CG1 3.83Å; L648-V679 HydrophobicContact CD1-CG2 3.85Å; V649-V679 PolarHBondContact O-N 3.19Å; I650-V679 WeakPolarHBondContact CA-O 3.09Å; I650-V679 HydrophobicContact CG1-CB 4.38Å; G651-V679 PolarHBondContact N-O 2.69Å; V677-V679 HydrophobicContact CG1-CG2 4.18Å; V679-V681 HydrophobicContact CG1-CG2 4.08Å; V679-V681 PolarHBondContact O-N 3.11Å; V679-Y711 HydrophobicContact CG1-CD1 3.9Å; V679-M716 HydrophobicContact CG1-CE 4.11Å
680D97.3Very high94.1Very high0 Ų024.1 Ų24.10%014%0.142CC..EExtended strand (participates in β ladder)trans-91.691.3179.1-164-2.6000110.1A682 I683 G687 I688 F689 T692 Y711D680-A682 VanDerWaalsContact C-N 3.27Å; D680-A682 PolarHBondContact O-N 2.96Å; D680-I683 WeakPolarHBondContact O-CB 3.34Å; D680-I683 WeakPolarHBondContact O-CG2 3.42Å; D680-I683 PolarHBondContact O-N 2.85Å; D680-G687 WeakPolarHBondContact OD2-CA 3.27Å; D680-I688 PolarHBondContact OD1-N 3.25Å; D680-I688 PolarHBondContact OD2-N 2.94Å; D680-F689 HydrophobicContact CB-CD2 3.75Å; D680-F689 HydrophobicContact CB-CE2 3.83Å; D680-F689 VanDerWaalsContact CG-CD2 3.46Å; D680-F689 WeakPolarHBondContact OD2-CD2 3.36Å; D680-T692 HydrophobicContact CB-CG2 4.21Å; D680-T692 WeakPolarHBondContact OD2-CB 3.4Å; D680-T692 PolarHBondContact OD2-OG1 2.87Å; D680-Y711 PolarHBondContact N-O 2.8Å
681V96Very high94Very high17 Ų1721.2 Ų21.210%0.10312%0.122CC..G310 helixtrans-70.8-28.7-177.2-173.50000111.1A551 A555 V593 I650 G651 V679 I683 M716A551-V681 HydrophobicContact CB-CG1 3.74Å; A555-V681 HydrophobicContact CB-CG2 3.79Å; V593-V681 HydrophobicContact CG1-CB 4.01Å; V593-V681 HydrophobicContact CG1-CG1 3.74Å; V593-V681 HydrophobicContact CG1-CG2 4.05Å; V593-V681 HydrophobicContact CG2-CG1 4.33Å; I650-V681 HydrophobicContact CG2-CG2 3.88Å; G651-V681 VanDerWaalsContact O-CB 3.27Å; G651-V681 WeakPolarHBondContact O-CB 3.5Å; G651-V681 PolarHBondContact O-N 3.3Å; V679-V681 HydrophobicContact CG1-CG2 4.08Å; V679-V681 PolarHBondContact O-N 3.11Å; V681-I683 PolarHBondContact O-N 2.91Å; V681-M716 HydrophobicContact CB-SD 4.44Å; V681-M716 HydrophobicContact CG1-SD 4.12Å; V681-M716 HydrophobicContact CG2-SD 4.13Å
682A91.8Very high93.8Very high7 Ų719.6 Ų19.66%0.05810%0.103CC..G310 helixtrans-83.213.2-178.200000113.8V653 A660 D680 D684 Q685 G686 G687 I688V653-A682 VanDerWaalsContact O-CB 3.31Å; V653-A682 WeakPolarHBondContact O-CB 3.34Å; A660-A682 HydrophobicContact CB-CB 4.2Å; D680-A682 VanDerWaalsContact C-N 3.27Å; D680-A682 PolarHBondContact O-N 2.96Å; A682-D684 PolarHBondContact O-N 2.88Å; A682-Q685 CarbonylContact O-C 3.54Å; A682-Q685 PolarHBondContact O-N 2.79Å; A682-G686 PolarHBondContact O-N 3.3Å; A682-G687 WeakPolarHBondContact O-CA 3.49Å; A682-G687 PolarHBondContact O-N 3.21Å; A682-I688 HydrophobicContact CB-CG2 4.07Å
683I90.6Very high93.1Very high10 Ų1024.5 Ų24.55%0.05113%0.13CC..G310 helixtrans-63.3-27.5-176.8-170.655.9000113.3D680 V681 Q685 G686 T692 V695 A712 A714D680-I683 WeakPolarHBondContact O-CB 3.34Å; D680-I683 WeakPolarHBondContact O-CG2 3.42Å; D680-I683 PolarHBondContact O-N 2.85Å; V681-I683 PolarHBondContact O-N 2.91Å; I683-Q685 PolarHBondContact O-N 3.05Å; I683-G686 PolarHBondContact O-N 3.39Å; I683-T692 HydrophobicContact CD1-CG2 3.51Å; I683-T692 HydrophobicContact CG1-CG2 4.31Å; I683-V695 HydrophobicContact CD1-CG2 4.26Å; I683-V695 HydrophobicContact CG1-CG1 4.49Å; I683-V695 HydrophobicContact CG1-CG2 4.01Å; I683-A712 HydrophobicContact CG1-CB 4.09Å; I683-A714 HydrophobicContact CG2-CB 4.15Å
684D82.5Confident92.6Very high46 Ų4629.8 Ų29.825%0.24615%0.151CC..G310 helixtrans-62.6-23173.763.9-27.8000112.9H510 A682 A714H510-D684 IonicContact CE1-OD2 3.05Å; H510-D684 PolarHBondContact CE1-OD2 2.68Å; H510-D684 IonicContact ND1-OD2 2.65Å; H510-D684 IonicContact NE2-OD2 3.16Å; A682-D684 PolarHBondContact O-N 2.88Å; D684-A714 HydrophobicContact CB-CB 4.39Å
685Q81Confident92.2Very high9 Ų927.9 Ų27.94%0.04215%0.149CC..G310 helixtrans-108.215.6172.7-60.8-72.49.100112.4H510 L654 R659 A660 A682 I683H510-Q685 PolarHBondContact ND1-NE2 2.99Å; L654-Q685 HydrophobicContact CD1-CG 3.81Å; R659-Q685 WeakPolarHBondContact CG-O 3.38Å; A660-Q685 HydrophobicContact CB-CB 4.11Å; A660-Q685 WeakPolarHBondContact CB-O 3.31Å; A660-Q685 PolarHBondContact N-O 3.24Å; A682-Q685 CarbonylContact O-C 3.54Å; A682-Q685 PolarHBondContact O-N 2.79Å; I683-Q685 PolarHBondContact O-N 3.05Å
686G81.6Confident92.1Very high24 Ų2426.8 Ų26.825%0.24714%0.144CC..THydrogen-bonded Turntrans106.2-9.917500000116.2A682 I683A682-G686 PolarHBondContact O-N 3.3Å; I683-G686 PolarHBondContact O-N 3.39Å
687G90.4Very high91.7Very high1 Ų129 Ų291%0.0116%0.158CC..  trans81.6154.5173.500000115.2D680 A682D680-G687 WeakPolarHBondContact OD2-CA 3.27Å; A682-G687 WeakPolarHBondContact O-CA 3.49Å; A682-G687 PolarHBondContact O-N 3.21Å
688I95.4Very high91.2Very high0 Ų031 Ų310%017%0.167CC..SBendtrans-98.1-9.8-178.173.1162.3000114.2I588 V653 A660 P661 L663 V664 D680 A682I588-I688 HydrophobicContact CB-CD1 3.98Å; I588-I688 HydrophobicContact CD1-CD1 4.29Å; I588-I688 HydrophobicContact CG2-CD1 4.04Å; V653-I688 HydrophobicContact CB-CG2 4.06Å; A660-I688 HydrophobicContact CB-CG2 4.41Å; P661-I688 WeakPolarHBondContact O-CA 3.29Å; L663-I688 PolarHBondContact N-O 3.47Å; V664-I688 PolarHBondContact N-O 3.43Å; V664-I688 VanDerWaalsContact N-O 3.1Å; D680-I688 PolarHBondContact OD1-N 3.25Å; D680-I688 PolarHBondContact OD2-N 2.94Å; A682-I688 HydrophobicContact CB-CG2 4.07Å
689F96.7Very high90.7Very high4 Ų435.3 Ų35.32%0.01819%0.19CC..BIsolated β-bridgetrans-105.2129.7-178.2-50.8-95.9000110V649 V664 I678 D680 T691 T692V649-F689 HydrophobicContact CG1-CE1 3.84Å; V649-F689 HydrophobicContact CG1-CZ 3.84Å; V664-F689 HydrophobicContact CB-CD1 3.53Å; V664-F689 HydrophobicContact CB-CE1 4.07Å; V664-F689 HydrophobicContact CB-CG 4.32Å; V664-F689 HydrophobicContact CG1-CD1 3.77Å; V664-F689 HydrophobicContact CG1-CE1 4.26Å; V664-F689 HydrophobicContact CG2-CD1 3.75Å; V664-F689 HydrophobicContact CG2-CE1 3.77Å; I678-F689 HydrophobicContact CD1-CD1 3.86Å; I678-F689 HydrophobicContact CD1-CE1 4.06Å; I678-F689 HydrophobicContact CD1-CG 4.44Å; I678-F689 HydrophobicContact CG1-CD1 4.41Å; I678-F689 HydrophobicContact CG1-CE1 4.15Å; I678-F689 HydrophobicContact CG2-CD1 4.04Å; I678-F689 HydrophobicContact CG2-CD2 3.62Å; I678-F689 HydrophobicContact CG2-CE1 3.86Å; I678-F689 HydrophobicContact CG2-CE2 3.41Å; I678-F689 VanDerWaalsContact CG2-CE2 3.41Å; I678-F689 HydrophobicContact CG2-CG 3.96Å; I678-F689 HydrophobicContact CG2-CZ 3.56Å; D680-F689 HydrophobicContact CB-CD2 3.75Å; D680-F689 HydrophobicContact CB-CE2 3.83Å; D680-F689 VanDerWaalsContact CG-CD2 3.46Å; D680-F689 WeakPolarHBondContact OD2-CD2 3.36Å; F689-T691 PolarHBondContact O-N 3.15Å; F689-T692 WeakPolarHBondContact CB-OG1 3.34Å; F689-T692 PolarHBondContact O-N 2.92Å
690E95.6Very high90.4Very high102 Ų10240.6 Ų40.648%0.47722%0.218SC..THydrogen-bonded Turntrans-60.8-29.8175.9-170.1-17517400112.1T662 V664 S665 K666 T692T662-E690 HydrophobicContact CG2-CB 3.82Å; V664-E690 PolarHBondContact O-N 2.87Å; S665-E690 WeakPolarHBondContact CA-OE2 3.29Å; K666-E690 PolarHBondContact N-OE2 2.84Å; E690-T692 VanDerWaalsContact C-N 3.31Å
691T95.8Very high90.2Very high1 Ų141.9 Ų41.91%0.00623%0.227CC..THydrogen-bonded Turntrans-74.1-20.617749.90000112.9K666 V669 F689 N693 K705 E706 H710K666-T691 HydrophobicContact CB-CG2 4.32Å; K666-T691 HydrophobicContact CG-CG2 4.08Å; V669-T691 HydrophobicContact CB-CG2 3.91Å; V669-T691 HydrophobicContact CG1-CG2 4.02Å; V669-T691 HydrophobicContact CG2-CG2 4.03Å; V669-T691 WeakPolarHBondContact CG2-OG1 3.28Å; F689-T691 PolarHBondContact O-N 3.15Å; T691-N693 PolarHBondContact O-N 3.24Å; T691-N693 PolarHBondContact O-OD1 2.81Å; T691-K705 HydrophobicContact CG2-CD 4.49Å; T691-K705 VanDerWaalsContact O-CD 3.31Å; T691-K705 WeakPolarHBondContact O-CD 3.33Å; T691-K705 PolarHBondContact O-NZ 2.91Å; T691-E706 HydrophobicContact CG2-CG 4.07Å; T691-H710 VanDerWaalsContact CB-NE2 3.29Å; T691-H710 WeakPolarHBondContact CB-NE2 3.35Å; T691-H710 PolarHBondContact OG1-NE2 3.35Å
692T91.5Very high90.2Very high10 Ų1043.3 Ų43.36%0.06124%0.236CC..  trans-76.570.7175.5-520000111.3D680 I683 F689 E690 Y703 A712D680-T692 HydrophobicContact CB-CG2 4.21Å; D680-T692 WeakPolarHBondContact OD2-CB 3.4Å; D680-T692 PolarHBondContact OD2-OG1 2.87Å; I683-T692 HydrophobicContact CD1-CG2 3.51Å; I683-T692 HydrophobicContact CG1-CG2 4.31Å; F689-T692 WeakPolarHBondContact CB-OG1 3.34Å; F689-T692 PolarHBondContact O-N 2.92Å; E690-T692 VanDerWaalsContact C-N 3.31Å; T692-Y703 VanDerWaalsContact CA-OH 3.23Å; T692-Y703 WeakPolarHBondContact CA-OH 3.5Å; T692-A712 HydrophobicContact CG2-CB 3.54Å
693N83.5Confident90.4Very high117 Ų11745 Ų4563%0.62624%0.241SC*.  trans-93.54.2-174.869-25.5000114.1T691 Y703 K705T691-N693 PolarHBondContact O-N 3.24Å; T691-N693 PolarHBondContact O-OD1 2.81Å; N693-Y703 PolarHBondContact N-OH 3.23Å; N693-K705 PolarHBondContact ND2-NZ 3.41Å; N693-K705 VanDerWaalsContact ND2-NZ 3.19Å; N693-K705 PolarHBondContact OD1-NZ 3.21Å
694K87.1Confident90.5Very high127 Ų12749.4 Ų49.455%0.55226%0.263SS*.SBendtrans-142.8132.6179.7172.4179175.8-172.90109.8Y703 A712K694-Y703 HydrophobicContact CB-CE1 4.37Å; K694-Y703 PolarHBondContact O-OH 2.89Å; K694-A712 WeakPolarHBondContact O-CB 3.42Å
695V89.7Confident91.1Very high81 Ų8149.7 Ų49.749%0.49126%0.262SS..  trans-74.4129.2165.7-174.60000109I683 A714I683-V695 HydrophobicContact CD1-CG2 4.26Å; I683-V695 HydrophobicContact CG1-CG1 4.49Å; I683-V695 HydrophobicContact CG1-CG2 4.01Å; V695-A714 HydrophobicContact CG1-CB 3.69Å
696T93.2Very high91.7Very high6 Ų652.3 Ų52.34%0.03728%0.275CS..BIsolated β-bridgetrans-98.5172.6176.456.50000111.8N700 P701 Y703 A712 V713T696-N700 VanDerWaalsContact CB-O 3.28Å; T696-N700 WeakPolarHBondContact CB-O 3.39Å; T696-P701 WeakPolarHBondContact CB-O 3.36Å; T696-P701 PolarHBondContact OG1-O 2.89Å; T696-Y703 HydrophobicContact CG2-CD1 3.54Å; T696-Y703 HydrophobicContact CG2-CE1 3.69Å; T696-A712 HydrophobicContact CG2-CB 4.28Å; T696-A712 PolarHBondContact N-O 2.75Å; T696-A712 WeakPolarHBondContact OG1-CA 3.15Å; T696-A712 PolarHBondContact OG1-N 2.82Å; T696-A712 VanDerWaalsContact OG1-N 3.1Å; T696-A712 PolarHBondContact OG1-O 2.83Å; T696-V713 WeakPolarHBondContact OG1-CG2 3.43Å; T696-V713 PolarHBondContact OG1-N 3.32Å; T696-V713 VanDerWaalsContact OG1-N 3.13Å
697T90.9Very high92.3Very high47 Ų4755.4 Ų55.429%0.28829%0.285SS..BIsolated β-bridgetrans-124.5163.7178.964.50000110.3D699 N700 P701T697-D699 PolarHBondContact O-N 2.93Å; T697-D699 VanDerWaalsContact O-N 3.16Å; T697-N700 CarbonylContact O-C 3.57Å; T697-N700 PolarHBondContact O-N 3.4Å; T697-N700 VanDerWaalsContact O-N 3.07Å; T697-N700 PolarHBondContact OG1-N 3Å; T697-P701 WeakPolarHBondContact O-CA 3.36Å
698H88.4Confident92.7Very high41 Ų4155.4 Ų55.419%0.1929%0.285CS..THydrogen-bonded Turntrans-57.3-28.5175.6-71.7-69.7000113.7N427 N715 A719N427-H698 HydrophobicContact CB-CB 3.85Å; H698-N715 PolarHBondContact NE2-O 3.47Å; H698-A719 VanDerWaalsContact CE1-CB 3.47Å; H698-A719 WeakPolarHBondContact CE1-CB 3.24Å
699D87.6Confident92.8Very high92 Ų9255.5 Ų55.549%0.49229%0.286SS..THydrogen-bonded Turntrans-75.3-31.2177.1-51.5-59000112.8N426 N427 T697N426-D699 PolarHBondContact ND2-OD2 2.95Å; N426-D699 PolarHBondContact OD1-OD2 3.21Å; N427-D699 VanDerWaalsContact ND2-CG 3.29Å; N427-D699 PolarHBondContact ND2-OD1 3.44Å; N427-D699 PolarHBondContact ND2-OD2 3.49Å; T697-D699 PolarHBondContact O-N 2.93Å; T697-D699 VanDerWaalsContact O-N 3.16Å
700N91.5Very high92.8Very high110 Ų11055.3 Ų55.359%0.58829%0.285SS*.BIsolated β-bridgetrans-133.569.2179.6-66.3-84.4000109T696 T697 T702T696-N700 VanDerWaalsContact CB-O 3.28Å; T696-N700 WeakPolarHBondContact CB-O 3.39Å; T697-N700 CarbonylContact O-C 3.57Å; T697-N700 PolarHBondContact O-N 3.4Å; T697-N700 VanDerWaalsContact O-N 3.07Å; T697-N700 PolarHBondContact OG1-N 3Å; N700-T702 VanDerWaalsContact C-N 3.29Å; N700-T702 PolarHBondContact O-N 2.93Å
701P93.8Very high92.9Very high28 Ų2850.8 Ų50.818%0.18226%0.264CS..  trans-72.3-22.3-16326.4-34.8000113.7F562 T696 T697 Y711 V713F562-P701 HydrophobicContact CE1-CG 4.29Å; F562-P701 HydrophobicContact CE2-CB 4.44Å; F562-P701 HydrophobicContact CE2-CG 4.45Å; F562-P701 HydrophobicContact CZ-CB 4.03Å; F562-P701 HydrophobicContact CZ-CG 3.59Å; T696-P701 WeakPolarHBondContact CB-O 3.36Å; T696-P701 PolarHBondContact OG1-O 2.89Å; T697-P701 WeakPolarHBondContact O-CA 3.36Å; P701-Y711 HydrophobicContact CB-CD2 3.88Å; P701-Y711 HydrophobicContact CB-CE2 3.62Å; P701-V713 HydrophobicContact CB-CG2 4Å
702T95.8Very high92.9Very high47 Ų4750.7 Ų50.729%0.28826%0.263SS..EExtended strand (participates in β ladder)trans-132159.7-171.963.30000114.5F562 N700 V709 H710 Y711F562-T702 HydrophobicContact CD1-CG2 3.65Å; F562-T702 HydrophobicContact CD2-CG2 4.05Å; F562-T702 HydrophobicContact CE1-CG2 3.52Å; F562-T702 HydrophobicContact CE2-CG2 3.92Å; F562-T702 HydrophobicContact CG-CG2 3.95Å; F562-T702 HydrophobicContact CZ-CG2 3.68Å; N700-T702 VanDerWaalsContact C-N 3.29Å; N700-T702 PolarHBondContact O-N 2.93Å; T702-V709 HydrophobicContact CG2-CG1 3.9Å; T702-H710 WeakPolarHBondContact CA-O 3.44Å; T702-H710 WeakPolarHBondContact CB-O 3.43Å; T702-Y711 HydrophobicContact CG2-CD2 4.03Å
703Y95Very high93Very high42 Ų4250.3 Ų50.317%0.16526%0.261CS..EExtended strand (participates in β ladder)trans-145.4163.2164.458.5-83.9000109.5T692 N693 K694 T696 K705 H710 A712T692-Y703 VanDerWaalsContact CA-OH 3.23Å; T692-Y703 WeakPolarHBondContact CA-OH 3.5Å; N693-Y703 PolarHBondContact N-OH 3.23Å; K694-Y703 HydrophobicContact CB-CE1 4.37Å; K694-Y703 PolarHBondContact O-OH 2.89Å; T696-Y703 HydrophobicContact CG2-CD1 3.54Å; T696-Y703 HydrophobicContact CG2-CE1 3.69Å; Y703-K705 HydrophobicContact CD2-CB 4.24Å; Y703-K705 HydrophobicContact CE2-CB 4.19Å; Y703-K705 HydrophobicContact CE2-CD 4.36Å; Y703-H710 HydrophobicContact CD1-CB 4.28Å; Y703-H710 HydrophobicContact CD2-CB 4.16Å; Y703-H710 HydrophobicContact CE1-CB 3.91Å; Y703-H710 HydrophobicContact CE2-CB 3.79Å; Y703-H710 AromaticContact CE2-CG 3.98Å; Y703-H710 HydrophobicContact CG-CB 4.41Å; Y703-H710 PolarHBondContact N-O 3.39Å; Y703-H710 VanDerWaalsContact N-O 3.14Å; Y703-H710 PolarHBondContact O-N 3.04Å; Y703-A712 HydrophobicContact CE1-CB 4.36Å
704I94.2Very high93.3Very high102 Ų10245.5 Ų45.552%0.52324%0.237SC..EExtended strand (participates in β ladder)trans-104.8130.8178.3-60.5176.5000109.2V708 V709I704-V708 WeakPolarHBondContact CA-O 3.29Å; I704-V709 HydrophobicContact CG1-CG2 4.4Å
705K93.8Very high93.5Very high52 Ų5239.8 Ų39.823%0.22621%0.213CC..EExtended strand (participates in β ladder)trans-147.8137.4174.3-170.1170.7172.6-174.80109.8T691 N693 Y703 N707 V708 H710T691-K705 HydrophobicContact CG2-CD 4.49Å; T691-K705 VanDerWaalsContact O-CD 3.31Å; T691-K705 WeakPolarHBondContact O-CD 3.33Å; T691-K705 PolarHBondContact O-NZ 2.91Å; N693-K705 PolarHBondContact ND2-NZ 3.41Å; N693-K705 VanDerWaalsContact ND2-NZ 3.19Å; N693-K705 PolarHBondContact OD1-NZ 3.21Å; Y703-K705 HydrophobicContact CD2-CB 4.24Å; Y703-K705 HydrophobicContact CE2-CB 4.19Å; Y703-K705 HydrophobicContact CE2-CD 4.36Å; K705-N707 PolarHBondContact O-N 3.44Å; K705-N707 VanDerWaalsContact O-N 3.15Å; K705-V708 PolarHBondContact N-O 2.84Å; K705-V708 PolarHBondContact O-N 3.17Å; K705-H710 PolarHBondContact O-CE1 3.27Å
706E94.6Very high93.8Very high64 Ų6436.2 Ų36.230%0.29919%0.191SC..THydrogen-bonded Turntrans50.334.1-169.7-51-50.8147.600112.9K666 V669 T691 V708K666-E706 WeakPolarHBondContact CE-OE1 3.27Å; K666-E706 HydrophobicContact CG-CG 4.32Å; K666-E706 IonicContact NZ-OE1 2.6Å; V669-E706 HydrophobicContact CG1-CB 4.17Å; T691-E706 HydrophobicContact CG2-CG 4.07Å; E706-V708 PolarHBondContact O-N 2.78Å
707N94.5Very high93.9Very high89 Ų8936.4 Ų36.448%0.47619%0.192SC..THydrogen-bonded Turntrans62.515.5-174.7-48.5-64.7000115.8F674 H675 K705F674-N707 HydrophobicContact CD2-CB 3.47Å; F674-N707 VanDerWaalsContact CD2-CB 3.47Å; F674-N707 HydrophobicContact CE2-CB 3.58Å; F674-N707 HydrophobicContact CG-CB 4.48Å; H675-N707 WeakPolarHBondContact CA-O 3.35Å; H675-N707 PolarHBondContact N-O 2.88Å; K705-N707 PolarHBondContact O-N 3.44Å; K705-N707 VanDerWaalsContact O-N 3.15Å
708V97.5Very high94Very high1 Ų134.2 Ų34.21%0.00618%0.179CC..EExtended strand (participates in β ladder)trans-109.6137177.2179.30000109.5V669 M672 S676 I678 I704 K705 E706 H710V669-V708 HydrophobicContact CG1-CB 4.15Å; V669-V708 HydrophobicContact CG1-CG2 3.93Å; M672-V708 HydrophobicContact CB-CG2 4Å; M672-V708 HydrophobicContact CE-CG1 4.07Å; M672-V708 HydrophobicContact SD-CG2 4.49Å; S676-V708 WeakPolarHBondContact O-CG1 3.49Å; I678-V708 HydrophobicContact CB-CG1 4.36Å; I678-V708 HydrophobicContact CD1-CG1 3.73Å; I678-V708 HydrophobicContact CG1-CG1 3.76Å; I704-V708 WeakPolarHBondContact CA-O 3.29Å; K705-V708 PolarHBondContact N-O 2.84Å; K705-V708 PolarHBondContact O-N 3.17Å; E706-V708 PolarHBondContact O-N 2.78Å; V708-H710 PolarHBondContact O-N 3.08Å; V708-H710 PolarHBondContact O-ND1 3.19Å
709V97.4Very high94.2Very high2 Ų234.7 Ų34.71%0.01219%0.19CC..EExtended strand (participates in β ladder)trans-78117.9176-178.10000108.5S676 V677 I678 T702 I704S676-V709 PolarHBondContact O-N 3.33Å; V677-V709 CarbonylContact C-O 3.57Å; V677-V709 WeakPolarHBondContact CA-O 3.41Å; V677-V709 HydrophobicContact CG2-CB 4.21Å; I678-V709 PolarHBondContact N-O 3.13Å; T702-V709 HydrophobicContact CG2-CG1 3.9Å; I704-V709 HydrophobicContact CG1-CG2 4.4Å
710H97.9Very high94.6Very high0 Ų032.6 Ų32.60%018%0.181CC..EExtended strand (participates in β ladder)trans-101.5124.3178.5-70.365.4000110T691 T702 Y703 K705 V708T691-H710 VanDerWaalsContact CB-NE2 3.29Å; T691-H710 WeakPolarHBondContact CB-NE2 3.35Å; T691-H710 PolarHBondContact OG1-NE2 3.35Å; T702-H710 WeakPolarHBondContact CA-O 3.44Å; T702-H710 WeakPolarHBondContact CB-O 3.43Å; Y703-H710 HydrophobicContact CD1-CB 4.28Å; Y703-H710 HydrophobicContact CD2-CB 4.16Å; Y703-H710 HydrophobicContact CE1-CB 3.91Å; Y703-H710 HydrophobicContact CE2-CB 3.79Å; Y703-H710 AromaticContact CE2-CG 3.98Å; Y703-H710 HydrophobicContact CG-CB 4.41Å; Y703-H710 PolarHBondContact N-O 3.39Å; Y703-H710 VanDerWaalsContact N-O 3.14Å; Y703-H710 PolarHBondContact O-N 3.04Å; K705-H710 PolarHBondContact O-CE1 3.27Å; V708-H710 PolarHBondContact O-N 3.08Å; V708-H710 PolarHBondContact O-ND1 3.19Å
711Y97.7Very high94.8Very high7 Ų728.3 Ų28.33%0.02716%0.159CC..EExtended strand (participates in β ladder)trans-107.4121.6167.6-178.2-78.3000108.9I558 F562 I678 V679 D680 P701 T702 V713 M716I558-Y711 HydrophobicContact CD1-CE1 4.39Å; I558-Y711 HydrophobicContact CD1-CE2 4.44Å; I558-Y711 HydrophobicContact CG2-CD1 4.24Å; I558-Y711 HydrophobicContact CG2-CD2 3.57Å; I558-Y711 HydrophobicContact CG2-CE1 4.22Å; I558-Y711 HydrophobicContact CG2-CE2 3.53Å; I558-Y711 HydrophobicContact CG2-CG 3.93Å; F562-Y711 AromaticContact CD2-CD2 3.94Å; F562-Y711 HydrophobicContact CD2-CD2 3.94Å; F562-Y711 AromaticContact CE2-CD2 3.5Å; F562-Y711 HydrophobicContact CE2-CD2 3.5Å; F562-Y711 VanDerWaalsContact CE2-CD2 3.5Å; F562-Y711 AromaticContact CE2-CE2 3.8Å; F562-Y711 HydrophobicContact CE2-CE2 3.8Å; F562-Y711 HydrophobicContact CZ-CD2 4.33Å; I678-Y711 PolarHBondContact O-N 2.81Å; V679-Y711 HydrophobicContact CG1-CD1 3.9Å; D680-Y711 PolarHBondContact N-O 2.8Å; P701-Y711 HydrophobicContact CB-CD2 3.88Å; P701-Y711 HydrophobicContact CB-CE2 3.62Å; T702-Y711 HydrophobicContact CG2-CD2 4.03Å; Y711-V713 HydrophobicContact CD1-CB 4.47Å; Y711-V713 HydrophobicContact CD1-CG2 4.4Å; Y711-V713 HydrophobicContact CD2-CG2 4.33Å; Y711-V713 HydrophobicContact CE1-CB 3.61Å; Y711-V713 HydrophobicContact CE1-CG2 3.76Å; Y711-V713 HydrophobicContact CE2-CB 4.39Å; Y711-V713 HydrophobicContact CE2-CG2 3.68Å; Y711-V713 WeakPolarHBondContact OH-CB 3.33Å; Y711-V713 WeakPolarHBondContact OH-CG2 3.42Å; Y711-M716 HydrophobicContact CE1-CE 4.15Å; Y711-M716 HydrophobicContact CE1-CG 3.9Å; Y711-M716 HydrophobicContact CE1-SD 4.11Å
712A95.5Very high94.9Very high0 Ų032.5 Ų32.50%018%0.176CC..  trans-140.538.2-168.500000112.1I683 T692 K694 T696 Y703 A714I683-A712 HydrophobicContact CG1-CB 4.09Å; T692-A712 HydrophobicContact CG2-CB 3.54Å; K694-A712 WeakPolarHBondContact O-CB 3.42Å; T696-A712 HydrophobicContact CG2-CB 4.28Å; T696-A712 PolarHBondContact N-O 2.75Å; T696-A712 WeakPolarHBondContact OG1-CA 3.15Å; T696-A712 PolarHBondContact OG1-N 2.82Å; T696-A712 VanDerWaalsContact OG1-N 3.1Å; T696-A712 PolarHBondContact OG1-O 2.83Å; Y703-A712 HydrophobicContact CE1-CB 4.36Å; A712-A714 PolarHBondContact O-N 2.89Å
713V94Very high94.9Very high2 Ų234 Ų341%0.01219%0.185CC..BIsolated β-bridgetrans-79.9118.7-177.6179.30000110.3T696 P701 Y711 N715 M716T696-V713 WeakPolarHBondContact OG1-CG2 3.43Å; T696-V713 PolarHBondContact OG1-N 3.32Å; T696-V713 VanDerWaalsContact OG1-N 3.13Å; P701-V713 HydrophobicContact CB-CG2 4Å; Y711-V713 HydrophobicContact CD1-CB 4.47Å; Y711-V713 HydrophobicContact CD1-CG2 4.4Å; Y711-V713 HydrophobicContact CD2-CG2 4.33Å; Y711-V713 HydrophobicContact CE1-CB 3.61Å; Y711-V713 HydrophobicContact CE1-CG2 3.76Å; Y711-V713 HydrophobicContact CE2-CB 4.39Å; Y711-V713 HydrophobicContact CE2-CG2 3.68Å; Y711-V713 WeakPolarHBondContact OH-CB 3.33Å; Y711-V713 WeakPolarHBondContact OH-CG2 3.42Å; V713-N715 VanDerWaalsContact C-N 3.29Å; V713-N715 WeakPolarHBondContact CG1-OD1 3.15Å; V713-N715 PolarHBondContact O-N 2.73Å; V713-M716 WeakPolarHBondContact O-CG 3.48Å
714A89.9Confident95Very high16 Ų1632 Ų3213%0.13218%0.177CC..THydrogen-bonded Turntrans-76.6-5.6-173.100000115.8I683 D684 V695 A712I683-A714 HydrophobicContact CG2-CB 4.15Å; D684-A714 HydrophobicContact CB-CB 4.39Å; V695-A714 HydrophobicContact CG1-CB 3.69Å; A712-A714 PolarHBondContact O-N 2.89Å
715N91Very high95.1Very high7 Ų727.1 Ų27.14%0.03715%0.152CC..THydrogen-bonded Turntrans-133.249.2-179.563.6-30.5000111.8N426 E428 H698 V713 P717 G718N426-N715 PolarHBondContact O-ND2 2.84Å; E428-N715 WeakPolarHBondContact OE2-CB 3.33Å; H698-N715 PolarHBondContact NE2-O 3.47Å; V713-N715 VanDerWaalsContact C-N 3.29Å; V713-N715 WeakPolarHBondContact CG1-OD1 3.15Å; V713-N715 PolarHBondContact O-N 2.73Å; N715-P717 VanDerWaalsContact C-CD 3.43Å; N715-P717 VanDerWaalsContact C-N 3.32Å; N715-G718 PolarHBondContact O-N 2.73Å
716M94.9Very high95.2Very high5 Ų528.5 Ų28.53%0.02516%0.157CC..G310 helixtrans-46.9-47179.9-61174.467.500113.7M554 A555 I558 V679 V681 Y711 V713 G718 A719M554-M716 HydrophobicContact CB-CE 4.06Å; M554-M716 WeakPolarHBondContact CE-O 3.31Å; A555-M716 HydrophobicContact CB-CE 4Å; I558-M716 HydrophobicContact CD1-CE 3.69Å; V679-M716 HydrophobicContact CG1-CE 4.11Å; V681-M716 HydrophobicContact CB-SD 4.44Å; V681-M716 HydrophobicContact CG1-SD 4.12Å; V681-M716 HydrophobicContact CG2-SD 4.13Å; Y711-M716 HydrophobicContact CE1-CE 4.15Å; Y711-M716 HydrophobicContact CE1-CG 3.9Å; Y711-M716 HydrophobicContact CE1-SD 4.11Å; V713-M716 WeakPolarHBondContact O-CG 3.48Å; M716-G718 PolarHBondContact O-N 2.77Å; M716-A719 PolarHBondContact O-N 3.18Å; M716-A719 VanDerWaalsContact O-N 3.16Å
717P95.2Very high95.3Very high11 Ų1126.8 Ų26.87%0.07115%0.153CC..G310 helixtrans-63-17.7-179.3-2235000114.5M547 I550 A551 N715 A719 V720 A724M547-P717 HydrophobicContact CB-CG 4.4Å; M547-P717 HydrophobicContact SD-CB 3.88Å; M547-P717 HydrophobicContact SD-CG 4.17Å; I550-P717 HydrophobicContact CG2-CB 3.86Å; I550-P717 HydrophobicContact CG2-CG 4.21Å; A551-P717 HydrophobicContact CB-CG 4.44Å; N715-P717 VanDerWaalsContact C-CD 3.43Å; N715-P717 VanDerWaalsContact C-N 3.32Å; P717-A719 PolarHBondContact O-N 3.26Å; P717-V720 CarbonylContact O-C 3.55Å; P717-V720 PolarHBondContact O-N 3.27Å; P717-V720 VanDerWaalsContact O-N 3.15Å; P717-A724 HydrophobicContact CB-CB 3.96Å; P717-A724 WeakPolarHBondContact O-CB 3.31Å
718G92.9Very high95.3Very high0 Ų022.6 Ų22.60%013%0.131CC..G310 helixtrans-63.5-18175.600000114.4N429 N715 M716N429-G718 PolarHBondContact ND2-O 2.75Å; N715-G718 PolarHBondContact O-N 2.73Å; M716-G718 PolarHBondContact O-N 2.77Å
719A94.1Very high95.2Very high52 Ų5222.7 Ų22.743%0.4313%0.131SC..G310 helixtrans-84.6-9.1175.200000114.1M554 H698 M716 P717M554-A719 HydrophobicContact CE-CB 3.93Å; H698-A719 VanDerWaalsContact CE1-CB 3.47Å; H698-A719 WeakPolarHBondContact CE1-CB 3.24Å; M716-A719 PolarHBondContact O-N 3.18Å; M716-A719 VanDerWaalsContact O-N 3.16Å; P717-A719 PolarHBondContact O-N 3.26Å
720V95.8Very high95.1Very high48 Ų4828.2 Ų28.229%0.29116%0.161SC..SBendtrans-125.754.1173.1-67.40000110.6I550 M554 P717 Q722 T723 A724I550-V720 HydrophobicContact CG2-CG2 3.61Å; M554-V720 HydrophobicContact CE-CG1 4.11Å; M554-V720 HydrophobicContact CE-CG2 4.22Å; M554-V720 HydrophobicContact SD-CG1 4.29Å; M554-V720 HydrophobicContact SD-CG2 3.5Å; M554-V720 VanDerWaalsContact SD-CG2 3.5Å; P717-V720 CarbonylContact O-C 3.55Å; P717-V720 PolarHBondContact O-N 3.27Å; P717-V720 VanDerWaalsContact O-N 3.15Å; V720-Q722 VanDerWaalsContact C-N 3.28Å; V720-Q722 PolarHBondContact O-N 3.47Å; V720-T723 PolarHBondContact O-N 3.26Å; V720-A724 PolarHBondContact O-N 3.35Å
721P96Very high95Very high20 Ų2029.4 Ų29.413%0.1317%0.171CC..Hα-helixtrans-61.4-35.1-165.827.7-37000112.7N429 R430 G457 T723 A724 T725N429-P721 VanDerWaalsContact C-CB 3.5Å; N429-P721 HydrophobicContact CB-CB 3.63Å; N429-P721 HydrophobicContact CB-CG 3.62Å; N429-P721 VanDerWaalsContact O-CB 3.32Å; N429-P721 WeakPolarHBondContact O-CB 3.18Å; R430-P721 HydrophobicContact CG-CB 4.14Å; G457-P721 WeakPolarHBondContact O-CG 2.87Å; P721-T723 VanDerWaalsContact C-N 3.33Å; P721-T723 PolarHBondContact O-N 3.28Å; P721-A724 PolarHBondContact O-N 3.26Å; P721-T725 WeakPolarHBondContact O-CB 3.43Å; P721-T725 PolarHBondContact O-N 2.76Å; P721-T725 PolarHBondContact O-OG1 3.38Å; P721-T725 VanDerWaalsContact O-OG1 3.09Å
722Q94.6Very high94.9Very high116 Ų11629.1 Ų29.154%0.54217%0.17SC..Hα-helixtrans-57.8-45.6175.7-165.8-84.2-3.400111V720 Y726V720-Q722 VanDerWaalsContact C-N 3.28Å; V720-Q722 PolarHBondContact O-N 3.47Å; Q722-Y726 WeakPolarHBondContact O-CD2 3.32Å
723T95.6Very high94.8Very high78 Ų7830.7 Ų30.748%0.47918%0.178SC..Hα-helixtrans-74.3-42.9177.3-55.90000111.8I550 V720 P721 A727I550-T723 HydrophobicContact CD1-CG2 4.23Å; V720-T723 PolarHBondContact O-N 3.26Å; P721-T723 VanDerWaalsContact C-N 3.33Å; P721-T723 PolarHBondContact O-N 3.28Å; T723-A727 WeakPolarHBondContact O-CB 3.5Å; T723-A727 PolarHBondContact O-N 2.96Å; T723-A727 VanDerWaalsContact O-N 3.09Å
724A96.8Very high94.8Very high0 Ų036.7 Ų36.70%021%0.205CC..Hα-helixtrans-73.4-35.4-171.200000113.6R430 M547 I550 P717 V720 P721 A727 L728R430-A724 VanDerWaalsContact CD-CB 3.42Å; R430-A724 HydrophobicContact CG-CB 3.91Å; M547-A724 HydrophobicContact CE-CB 4.21Å; M547-A724 WeakPolarHBondContact CE-O 3.46Å; M547-A724 HydrophobicContact SD-CB 4.3Å; I550-A724 VanDerWaalsContact CD1-CA 3.49Å; I550-A724 HydrophobicContact CD1-CB 3.69Å; P717-A724 HydrophobicContact CB-CB 3.96Å; P717-A724 WeakPolarHBondContact O-CB 3.31Å; V720-A724 PolarHBondContact O-N 3.35Å; P721-A724 PolarHBondContact O-N 3.26Å; A724-A727 PolarHBondContact O-N 3.32Å; A724-L728 VanDerWaalsContact O-CB 3.27Å; A724-L728 WeakPolarHBondContact O-CB 3.31Å; A724-L728 PolarHBondContact O-N 3.37Å
725T96.7Very high95.1Very high0 Ų036.7 Ų36.70%020%0.202CC..Hα-helixtrans-60.1-50.8175.8-740000111.3R430 V431 P434 S458 I460 P721 L728 S729R430-T725 WeakPolarHBondContact CA-OG1 3.15Å; V431-T725 HydrophobicContact CG1-CG2 3.61Å; V431-T725 PolarHBondContact N-OG1 3.15Å; V431-T725 VanDerWaalsContact N-OG1 3.14Å; V431-T725 WeakPolarHBondContact O-CG2 3.33Å; P434-T725 HydrophobicContact CB-CG2 4.02Å; P434-T725 HydrophobicContact CG-CG2 4.26Å; S458-T725 PolarHBondContact OG-OG1 3Å; I460-T725 HydrophobicContact CD1-CG2 4.31Å; P721-T725 WeakPolarHBondContact O-CB 3.43Å; P721-T725 PolarHBondContact O-N 2.76Å; P721-T725 PolarHBondContact O-OG1 3.38Å; P721-T725 VanDerWaalsContact O-OG1 3.09Å; T725-L728 PolarHBondContact O-N 3.09Å; T725-S729 VanDerWaalsContact O-CB 3.3Å; T725-S729 WeakPolarHBondContact O-CB 3.43Å; T725-S729 PolarHBondContact O-N 3.3Å
726Y96.2Very high95.4Very high81 Ų8136.3 Ų36.332%0.31820%0.2SC..Hα-helixtrans-68.9-38.9178.9-70.6-80.5000112.1P434 Q722 L728 S729 N730P434-Y726 HydrophobicContact CB-CD1 4.14Å; P434-Y726 HydrophobicContact CB-CE1 3.72Å; P434-Y726 HydrophobicContact CG-CD1 3.92Å; P434-Y726 HydrophobicContact CG-CE1 3.96Å; Q722-Y726 WeakPolarHBondContact O-CD2 3.32Å; Y726-L728 PolarHBondContact O-N 2.88Å; Y726-S729 PolarHBondContact O-N 3.04Å; Y726-N730 VanDerWaalsContact O-CB 3.29Å; Y726-N730 WeakPolarHBondContact O-CB 3.39Å; Y726-N730 PolarHBondContact O-N 3Å; Y726-N730 PolarHBondContact O-ND2 2.91Å; Y726-N730 PolarHBondContact O-OD1 3.34Å
727A96.1Very high95.2Very high28 Ų2838.2 Ų38.223%0.23121%0.21CC..Hα-helixtrans-62.2-42.2177.100000112.2P546 M547 I550 T723 A724P546-A727 HydrophobicContact CB-CB 3.98Å; M547-A727 HydrophobicContact CE-CB 4.16Å; I550-A727 HydrophobicContact CD1-CB 3.96Å; T723-A727 WeakPolarHBondContact O-CB 3.5Å; T723-A727 PolarHBondContact O-N 2.96Å; T723-A727 VanDerWaalsContact O-N 3.09Å; A724-A727 PolarHBondContact O-N 3.32Å
728L96.5Very high95.1Very high1 Ų140 Ų401%0.00522%0.219CC..Hα-helixtrans-66.3-52.3175.3-178.659.7000110.9V488 Y508 Y531 M547 A724 T725 Y726 N730 A731 T732V488-L728 HydrophobicContact CG1-CD2 4.02Å; V488-L728 HydrophobicContact CG2-CD2 4.2Å; Y508-L728 HydrophobicContact CE2-CD1 3.97Å; Y508-L728 HydrophobicContact CE2-CD2 4.37Å; Y531-L728 HydrophobicContact CD2-CD1 4.18Å; Y531-L728 HydrophobicContact CE2-CD1 4.32Å; Y531-L728 HydrophobicContact CE2-CD2 4.29Å; M547-L728 HydrophobicContact CE-CB 3.78Å; M547-L728 HydrophobicContact CG-CD1 4.39Å; M547-L728 HydrophobicContact SD-CB 4.41Å; A724-L728 VanDerWaalsContact O-CB 3.27Å; A724-L728 WeakPolarHBondContact O-CB 3.31Å; A724-L728 PolarHBondContact O-N 3.37Å; T725-L728 PolarHBondContact O-N 3.09Å; Y726-L728 PolarHBondContact O-N 2.88Å; L728-N730 VanDerWaalsContact C-N 3.32Å; L728-N730 PolarHBondContact O-N 2.66Å; L728-A731 PolarHBondContact O-N 3.18Å; L728-T732 HydrophobicContact CD1-CG2 3.85Å; L728-T732 HydrophobicContact CG-CG2 4.17Å; L728-T732 WeakPolarHBondContact O-CG2 3.24Å; L728-T732 PolarHBondContact O-N 2.91Å; L728-T732 PolarHBondContact O-OG1 3.4Å
729S95.5Very high95.3Very high2 Ų240.5 Ų40.51%0.01422%0.222CC..Hα-helixtrans-60.3-40-176.7175.90000112.7P434 T725 Y726 A731 T732 M733P434-S729 WeakPolarHBondContact CD-OG 3.4Å; T725-S729 VanDerWaalsContact O-CB 3.3Å; T725-S729 WeakPolarHBondContact O-CB 3.43Å; T725-S729 PolarHBondContact O-N 3.3Å; Y726-S729 PolarHBondContact O-N 3.04Å; S729-A731 PolarHBondContact O-N 3.36Å; S729-T732 WeakPolarHBondContact CA-OG1 3.13Å; S729-T732 PolarHBondContact O-N 3.44Å; S729-T732 PolarHBondContact O-OG1 2.96Å; S729-M733 WeakPolarHBondContact O-CB 3.41Å; S729-M733 PolarHBondContact O-N 3.38Å
730N93.9Very high95.2Very high118 Ų11839.2 Ų39.263%0.63121%0.211SC*.Hα-helixtrans-60.6-33.9176.9-71.7-12.4000112.2Y726 L728Y726-N730 VanDerWaalsContact O-CB 3.29Å; Y726-N730 WeakPolarHBondContact O-CB 3.39Å; Y726-N730 PolarHBondContact O-N 3Å; Y726-N730 PolarHBondContact O-ND2 2.91Å; Y726-N730 PolarHBondContact O-OD1 3.34Å; L728-N730 VanDerWaalsContact C-N 3.32Å; L728-N730 PolarHBondContact O-N 2.66Å
731A95.3Very high94.8Very high25 Ų2540.7 Ų40.721%0.20722%0.217CC..Hα-helixtrans-79.2-37.8176.700000112.1L543 P546 L728 S729L543-A731 VanDerWaalsContact CD2-C 3.41Å; L543-A731 HydrophobicContact CD2-CB 3.97Å; L543-A731 WeakPolarHBondContact CD2-O 3.5Å; P546-A731 HydrophobicContact CG-CB 3.91Å; L728-A731 PolarHBondContact O-N 3.18Å; S729-A731 PolarHBondContact O-N 3.36Å
732T96.5Very high94.5Very high1 Ų143.5 Ų43.51%0.00623%0.231CC..Hα-helixtrans-79.6-25.9-176.459.50000113.4Y531 L543 L728 S729 E734 Y735 V736Y531-T732 HydrophobicContact CD1-CG2 4.44Å; Y531-T732 HydrophobicContact CE1-CG2 4.16Å; Y531-T732 HydrophobicContact CE2-CG2 4.25Å; L543-T732 HydrophobicContact CD1-CG2 4.44Å; L543-T732 HydrophobicContact CD2-CG2 4.01Å; L728-T732 HydrophobicContact CD1-CG2 3.85Å; L728-T732 HydrophobicContact CG-CG2 4.17Å; L728-T732 WeakPolarHBondContact O-CG2 3.24Å; L728-T732 PolarHBondContact O-N 2.91Å; L728-T732 PolarHBondContact O-OG1 3.4Å; S729-T732 WeakPolarHBondContact CA-OG1 3.13Å; S729-T732 PolarHBondContact O-N 3.44Å; S729-T732 PolarHBondContact O-OG1 2.96Å; T732-E734 VanDerWaalsContact C-N 3.3Å; T732-E734 PolarHBondContact O-N 3.31Å; T732-Y735 WeakPolarHBondContact O-CB 3.35Å; T732-Y735 PolarHBondContact O-N 3.48Å; T732-V736 WeakPolarHBondContact O-CG2 3.36Å; T732-V736 PolarHBondContact O-N 3.08Å
733M93.6Very high94.3Very high34 Ų3442.5 Ų42.517%0.16723%0.229CC..Hα-helixtrans-56.7-38.4-169-163.666.8-120.700114L433 L441 S729 Y735 V736 N737L433-M733 HydrophobicContact CD1-SD 3.95Å; L441-M733 HydrophobicContact CD1-CE 4.48Å; L441-M733 HydrophobicContact CD2-CE 3.91Å; L441-M733 HydrophobicContact CG-CE 3.84Å; S729-M733 WeakPolarHBondContact O-CB 3.41Å; S729-M733 PolarHBondContact O-N 3.38Å; M733-Y735 VanDerWaalsContact C-N 3.33Å; M733-Y735 PolarHBondContact O-N 3.34Å; M733-V736 HydrophobicContact CE-CB 4.11Å; M733-V736 HydrophobicContact CE-CG1 3.9Å; M733-V736 PolarHBondContact O-N 2.88Å; M733-N737 WeakPolarHBondContact CE-OD1 3.4Å; M733-N737 WeakPolarHBondContact O-CB 3.33Å; M733-N737 PolarHBondContact O-N 2.84Å; M733-N737 PolarHBondContact O-ND2 3.31Å
734E93.1Very high94.1Very high128 Ų12840.1 Ų40.160%0.59821%0.214SC*.Hα-helixtrans-57.6-47.3175.5-176.8-175.3161.900111.3T732 N737 L738T732-E734 VanDerWaalsContact C-N 3.3Å; T732-E734 PolarHBondContact O-N 3.31Å; E734-N737 PolarHBondContact O-N 2.86Å; E734-L738 WeakPolarHBondContact O-CG 3.34Å; E734-L738 PolarHBondContact O-N 2.93Å
735Y96.8Very high93.9Very high15 Ų1542.7 Ų42.76%0.05923%0.227CC..Hα-helixtrans-73.4-38.2-179.1-60.8-83.4000112.4V534 P542 L543 T732 M733 N737 L738 L739 A753 L754V534-Y735 HydrophobicContact CG1-CD1 3.95Å; V534-Y735 HydrophobicContact CG1-CE1 3.43Å; V534-Y735 VanDerWaalsContact CG1-CE1 3.43Å; V534-Y735 HydrophobicContact CG1-CE2 4.29Å; P542-Y735 HydrophobicContact CG-CE2 4.46Å; P542-Y735 WeakPolarHBondContact CG-OH 3.42Å; L543-Y735 HydrophobicContact CD1-CD2 4.13Å; L543-Y735 HydrophobicContact CD1-CE2 4.47Å; L543-Y735 HydrophobicContact CD1-CG 4.43Å; L543-Y735 HydrophobicContact CD2-CD2 3.61Å; L543-Y735 HydrophobicContact CD2-CE2 3.66Å; L543-Y735 HydrophobicContact CG-CD2 4.23Å; L543-Y735 HydrophobicContact CG-CE2 4.18Å; T732-Y735 WeakPolarHBondContact O-CB 3.35Å; T732-Y735 PolarHBondContact O-N 3.48Å; M733-Y735 VanDerWaalsContact C-N 3.33Å; M733-Y735 PolarHBondContact O-N 3.34Å; Y735-N737 VanDerWaalsContact C-N 3.29Å; Y735-N737 PolarHBondContact O-N 3.43Å; Y735-L738 PolarHBondContact O-N 3.19Å; Y735-L739 WeakPolarHBondContact O-CB 3.34Å; Y735-L739 VanDerWaalsContact O-CG 3.29Å; Y735-L739 WeakPolarHBondContact O-CG 3.46Å; Y735-L739 PolarHBondContact O-N 2.81Å; Y735-A753 HydrophobicContact CE1-CB 4.02Å; Y735-L754 HydrophobicContact CD1-CD1 4.34Å; Y735-L754 HydrophobicContact CD1-CD2 3.65Å; Y735-L754 HydrophobicContact CD1-CG 3.8Å; Y735-L754 HydrophobicContact CE1-CG 4.45Å; Y735-L754 HydrophobicContact CG-CD2 4.31Å
736V96.5Very high93.6Very high0 Ų045.7 Ų45.70%025%0.248CC..Hα-helixtrans-58.8-44.7173.4173.50000110L441 M484 L486 F506 T732 M733 L739 A740L441-V736 HydrophobicContact CD1-CG1 3.96Å; L441-V736 HydrophobicContact CD2-CG1 4.15Å; L441-V736 HydrophobicContact CG-CG1 4.47Å; M484-V736 HydrophobicContact CE-CG1 4.08Å; L486-V736 HydrophobicContact CD1-CG1 3.85Å; L486-V736 HydrophobicContact CD1-CG2 4.18Å; L486-V736 HydrophobicContact CD2-CG1 4.47Å; L486-V736 HydrophobicContact CD2-CG2 4.03Å; F506-V736 HydrophobicContact CD1-CG2 4.03Å; F506-V736 HydrophobicContact CE1-CG2 3.85Å; T732-V736 WeakPolarHBondContact O-CG2 3.36Å; T732-V736 PolarHBondContact O-N 3.08Å; M733-V736 HydrophobicContact CE-CB 4.11Å; M733-V736 HydrophobicContact CE-CG1 3.9Å; M733-V736 PolarHBondContact O-N 2.88Å; V736-L739 PolarHBondContact O-N 3.14Å; V736-A740 VanDerWaalsContact O-CB 3.29Å; V736-A740 WeakPolarHBondContact O-CB 3.48Å; V736-A740 PolarHBondContact O-N 2.89Å
737N91.3Very high93.6Very high45 Ų4542.5 Ų42.524%0.24124%0.236CC..Hα-helixtrans-63.5-42.4175.6-76.6-28.5000112.1M733 E734 Y735 A740 N741M733-N737 WeakPolarHBondContact CE-OD1 3.4Å; M733-N737 WeakPolarHBondContact O-CB 3.33Å; M733-N737 PolarHBondContact O-N 2.84Å; M733-N737 PolarHBondContact O-ND2 3.31Å; E734-N737 PolarHBondContact O-N 2.86Å; Y735-N737 VanDerWaalsContact C-N 3.29Å; Y735-N737 PolarHBondContact O-N 3.43Å; N737-A740 PolarHBondContact O-N 3.06Å; N737-N741 WeakPolarHBondContact O-CB 3.32Å; N737-N741 PolarHBondContact O-N 3.26Å; N737-N741 VanDerWaalsContact O-N 3.1Å; N737-N741 PolarHBondContact O-ND2 2.94Å
738L94Very high93.5Very high47 Ų4741.1 Ų41.125%0.24623%0.225CC..Hα-helixtrans-61.2-47.4176.9-72.9171.3000111.6E734 Y735 N741 N742 L747 N751 L754E734-L738 WeakPolarHBondContact O-CG 3.34Å; E734-L738 PolarHBondContact O-N 2.93Å; Y735-L738 PolarHBondContact O-N 3.19Å; L738-N741 PolarHBondContact O-N 3.12Å; L738-N742 WeakPolarHBondContact O-CB 3.48Å; L738-N742 PolarHBondContact O-N 3.4Å; L738-N742 PolarHBondContact O-ND2 3.33Å; L738-L747 HydrophobicContact CB-CD1 4.16Å; L738-L747 HydrophobicContact CB-CD2 4.06Å; L738-L747 HydrophobicContact CD2-CD1 4.38Å; L738-L747 WeakPolarHBondContact O-CD2 3.32Å; L738-N751 WeakPolarHBondContact CD1-ND2 3.4Å; L738-L754 HydrophobicContact CB-CD1 4.21Å; L738-L754 HydrophobicContact CD1-CD1 4.32Å
739L95.9Very high93.3Very high12 Ų1246.6 Ų46.66%0.06325%0.249CC..Hα-helixtrans-64.7-40.3-179.9-69.3166000112.2M484 L504 F506 I529 Y735 V736 L744 L747 L754M484-L739 HydrophobicContact SD-CB 3.8Å; M484-L739 HydrophobicContact SD-CD1 4.49Å; L504-L739 HydrophobicContact CD2-CB 4.14Å; L504-L739 HydrophobicContact CD2-CD2 3.98Å; L504-L739 HydrophobicContact CD2-CG 4.44Å; F506-L739 HydrophobicContact CB-CD1 4.36Å; F506-L739 HydrophobicContact CD1-CD1 3.55Å; F506-L739 HydrophobicContact CD2-CD1 4.15Å; F506-L739 HydrophobicContact CE1-CD1 3.79Å; F506-L739 HydrophobicContact CE2-CD1 4.34Å; F506-L739 HydrophobicContact CG-CD1 3.77Å; F506-L739 HydrophobicContact CZ-CD1 4.19Å; I529-L739 HydrophobicContact CD1-CD1 4.37Å; I529-L739 HydrophobicContact CD1-CD2 3.63Å; Y735-L739 WeakPolarHBondContact O-CB 3.34Å; Y735-L739 VanDerWaalsContact O-CG 3.29Å; Y735-L739 WeakPolarHBondContact O-CG 3.46Å; Y735-L739 PolarHBondContact O-N 2.81Å; V736-L739 PolarHBondContact O-N 3.14Å; L739-L744 HydrophobicContact CD2-CD1 3.98Å; L739-L747 HydrophobicContact CD2-CD2 3.85Å; L739-L747 HydrophobicContact CG-CD2 4.32Å; L739-L754 HydrophobicContact CD1-CD2 4.26Å; L739-L754 HydrophobicContact CD2-CD1 4.18Å; L739-L754 HydrophobicContact CD2-CD2 4.4Å; L739-L754 HydrophobicContact CG-CD1 4.29Å; L739-L754 HydrophobicContact CG-CD2 4.39Å
740A91.7Very high93.1Very high25 Ų2553.2 Ų53.221%0.20728%0.284CS..Hα-helixtrans-70.7-30.818000000113.3L441 H446 M484 V736 N737L441-A740 HydrophobicContact CD2-CB 4.13Å; H446-A740 PolarHBondContact CE1-O 3.42Å; M484-A740 HydrophobicContact CE-CB 4.08Å; V736-A740 VanDerWaalsContact O-CB 3.29Å; V736-A740 WeakPolarHBondContact O-CB 3.48Å; V736-A740 PolarHBondContact O-N 2.89Å; N737-A740 PolarHBondContact O-N 3.06Å
741N87.5Confident93.1Very high78 Ų7849.3 Ų49.342%0.41726%0.263SS..Hα-helixtrans-100.6-2.7-171.6-68-64.3000114.9H446 N737 L738H446-N741 PolarHBondContact NE2-OD1 3.43Å; N737-N741 WeakPolarHBondContact O-CB 3.32Å; N737-N741 PolarHBondContact O-N 3.26Å; N737-N741 VanDerWaalsContact O-N 3.1Å; N737-N741 PolarHBondContact O-ND2 2.94Å; L738-N741 PolarHBondContact O-N 3.12Å
742N90.4Very high93.1Very high80 Ų8051.2 Ų51.243%0.42827%0.27SS..SBendtrans-133.7149.9-173.3-61.5-90.5000111.7L738 L744 L747L738-N742 WeakPolarHBondContact O-CB 3.48Å; L738-N742 PolarHBondContact O-N 3.4Å; L738-N742 PolarHBondContact O-ND2 3.33Å; N742-L744 PolarHBondContact O-N 3.32Å; N742-L747 HydrophobicContact CB-CB 4.11Å; N742-L747 HydrophobicContact CB-CD2 4.35Å
743D90.5Very high93.1Very high94 Ų9451.6 Ų51.650%0.50327%0.273SS..  trans-57.5129.4165.4168.167.4000110.4I745 S746 L747D743-I745 PolarHBondContact O-N 2.9Å; D743-I745 PolarHBondContact OD2-N 3.29Å; D743-S746 PolarHBondContact O-N 3.39Å; D743-S746 WeakPolarHBondContact OD2-CB 3.34Å; D743-S746 PolarHBondContact OD2-N 2.96Å; D743-S746 PolarHBondContact OD2-OG 3.23Å; D743-L747 WeakPolarHBondContact O-CB 3.45Å; D743-L747 PolarHBondContact O-N 2.85Å
744L92.1Very high93.2Very high29 Ų2950 Ų5015%0.15227%0.265CS..Hα-helixtrans-60-44.7-17217962.6000112.1L504 H527 I529 L739 N742 L747 L748 Y761L504-L744 HydrophobicContact CD1-CD1 4.21Å; L504-L744 HydrophobicContact CD1-CD2 4.3Å; L504-L744 HydrophobicContact CD2-CD1 4.47Å; H527-L744 HydrophobicContact CB-CD2 4.05Å; H527-L744 WeakPolarHBondContact ND1-CD2 3.43Å; I529-L744 HydrophobicContact CD1-CD1 4.28Å; L739-L744 HydrophobicContact CD2-CD1 3.98Å; N742-L744 PolarHBondContact O-N 3.32Å; L744-L747 PolarHBondContact O-N 3.14Å; L744-L748 HydrophobicContact CD1-CD1 3.77Å; L744-L748 HydrophobicContact CD1-CG 4.01Å; L744-L748 HydrophobicContact CG-CD1 3.81Å; L744-L748 HydrophobicContact CG-CG 4.41Å; L744-L748 WeakPolarHBondContact O-CB 3.49Å; L744-L748 WeakPolarHBondContact O-CG 3.43Å; L744-L748 PolarHBondContact O-N 3.41Å; L744-Y761 HydrophobicContact CD2-CE2 4.45Å
745I92.3Very high93.3Very high53 Ų5346.7 Ų46.727%0.27225%0.247SC..Hα-helixtrans-65.2-46.8-176.6-62.9175.5000110D743 L748 K749 Y761D743-I745 PolarHBondContact O-N 2.9Å; D743-I745 PolarHBondContact OD2-N 3.29Å; I745-L748 PolarHBondContact O-N 3.32Å; I745-K749 HydrophobicContact CG2-CD 4.35Å; I745-K749 WeakPolarHBondContact O-CG 3.34Å; I745-K749 PolarHBondContact O-N 3.45Å; I745-K749 VanDerWaalsContact O-N 3.08Å; I745-Y761 WeakPolarHBondContact CD1-OH 3.29Å; I745-Y761 WeakPolarHBondContact CG1-OH 3.41Å
746S91.1Very high93.2Very high63 Ų6350 Ų5044%0.44126%0.259SS..Hα-helixtrans-62.1-46.3178.8-55.90000111D743 L748 K749 D750D743-S746 PolarHBondContact O-N 3.39Å; D743-S746 WeakPolarHBondContact OD2-CB 3.34Å; D743-S746 PolarHBondContact OD2-N 2.96Å; D743-S746 PolarHBondContact OD2-OG 3.23Å; S746-L748 PolarHBondContact O-N 3.16Å; S746-K749 WeakPolarHBondContact O-CB 3.15Å; S746-K749 PolarHBondContact O-N 3Å; S746-D750 PolarHBondContact O-N 3Å
747L94.3Very high93.2Very high14 Ų1450 Ų507%0.07326%0.259CS..Hα-helixtrans-60.3-44.3177.1178.862000112.1L738 L739 N742 D743 L744 K749 D750 N751 L754L738-L747 HydrophobicContact CB-CD1 4.16Å; L738-L747 HydrophobicContact CB-CD2 4.06Å; L738-L747 HydrophobicContact CD2-CD1 4.38Å; L738-L747 WeakPolarHBondContact O-CD2 3.32Å; L739-L747 HydrophobicContact CD2-CD2 3.85Å; L739-L747 HydrophobicContact CG-CD2 4.32Å; N742-L747 HydrophobicContact CB-CB 4.11Å; N742-L747 HydrophobicContact CB-CD2 4.35Å; D743-L747 WeakPolarHBondContact O-CB 3.45Å; D743-L747 PolarHBondContact O-N 2.85Å; L744-L747 PolarHBondContact O-N 3.14Å; L747-K749 VanDerWaalsContact C-N 3.29Å; L747-K749 PolarHBondContact O-N 3.28Å; L747-D750 PolarHBondContact O-N 3.37Å; L747-N751 HydrophobicContact CD1-CB 3.88Å; L747-N751 HydrophobicContact CG-CB 4.41Å; L747-N751 WeakPolarHBondContact O-CB 3.47Å; L747-N751 PolarHBondContact O-N 2.88Å; L747-L754 HydrophobicContact CD1-CD1 4.12Å; L747-L754 HydrophobicContact CD2-CD1 3.56Å; L747-L754 HydrophobicContact CG-CD1 3.83Å
748L94.9Very high93.5Very high0 Ų047.9 Ų47.90%025%0.248CC..Hα-helixtrans-66-31.8179.1-69.3169.8000111.8I529 L744 I745 S746 D750 L754 R755 L758 L785I529-L748 HydrophobicContact CD1-CD2 4.31Å; L744-L748 HydrophobicContact CD1-CD1 3.77Å; L744-L748 HydrophobicContact CD1-CG 4.01Å; L744-L748 HydrophobicContact CG-CD1 3.81Å; L744-L748 HydrophobicContact CG-CG 4.41Å; L744-L748 WeakPolarHBondContact O-CB 3.49Å; L744-L748 WeakPolarHBondContact O-CG 3.43Å; L744-L748 PolarHBondContact O-N 3.41Å; I745-L748 PolarHBondContact O-N 3.32Å; S746-L748 PolarHBondContact O-N 3.16Å; L748-D750 VanDerWaalsContact C-N 3.32Å; L748-D750 PolarHBondContact O-N 2.86Å; L748-L754 HydrophobicContact CD2-CB 4.12Å; L748-R755 VanDerWaalsContact O-CZ 3.24Å; L748-R755 PolarHBondContact O-NE 3.12Å; L748-R755 PolarHBondContact O-NH2 3.14Å; L748-R755 VanDerWaalsContact O-NH2 3.07Å; L748-L758 HydrophobicContact CD1-CD1 4.1Å; L748-L758 HydrophobicContact CD1-CD2 4.01Å; L748-L758 HydrophobicContact CD2-CB 4.46Å; L748-L785 HydrophobicContact CB-CD1 4.06Å; L748-L785 HydrophobicContact CD1-CD2 3.97Å
749K91.7Very high93.6Very high115 Ų11545.7 Ų45.750%0.524%0.236SC..Hα-helixtrans-69.3-25.9175.2-75.8174.9179.7175.50114.1I745 S746 L747 R755I745-K749 HydrophobicContact CG2-CD 4.35Å; I745-K749 WeakPolarHBondContact O-CG 3.34Å; I745-K749 PolarHBondContact O-N 3.45Å; I745-K749 VanDerWaalsContact O-N 3.08Å; S746-K749 WeakPolarHBondContact O-CB 3.15Å; S746-K749 PolarHBondContact O-N 3Å; L747-K749 VanDerWaalsContact C-N 3.29Å; L747-K749 PolarHBondContact O-N 3.28Å; K749-R755 PolarHBondContact O-NH2 2.89Å
750D91.5Very high93.7Very high142 Ų14245.1 Ų45.176%0.75923%0.233SC*.Hα-helixtrans-108-28-175.5-66.4-21.2000113.4S746 L747 L748S746-D750 PolarHBondContact O-N 3Å; L747-D750 PolarHBondContact O-N 3.37Å; L748-D750 VanDerWaalsContact C-N 3.32Å; L748-D750 PolarHBondContact O-N 2.86Å
751N94.4Very high93.9Very high35 Ų3544.4 Ų44.419%0.18723%0.225CC..  trans-100.1102.9-178.5-168.1-57.4000111.6L738 L747 A753 L754 R755L738-N751 WeakPolarHBondContact CD1-ND2 3.4Å; L747-N751 HydrophobicContact CD1-CB 3.88Å; L747-N751 HydrophobicContact CG-CB 4.41Å; L747-N751 WeakPolarHBondContact O-CB 3.47Å; L747-N751 PolarHBondContact O-N 2.88Å; N751-A753 VanDerWaalsContact C-N 3.3Å; N751-A753 PolarHBondContact O-N 3.38Å; N751-A753 WeakPolarHBondContact OD1-CB 3.47Å; N751-A753 PolarHBondContact OD1-N 3.27Å; N751-L754 HydrophobicContact CB-CB 4.34Å; N751-L754 HydrophobicContact CB-CD1 4.39Å; N751-L754 PolarHBondContact OD1-N 3.46Å; N751-R755 VanDerWaalsContact O-CB 3.32Å; N751-R755 WeakPolarHBondContact O-CB 3.38Å; N751-R755 PolarHBondContact O-N 3.18Å
752L94.8Very high94.2Very high66 Ų6643.4 Ų43.435%0.34622%0.22SC..Hα-helixtrans-59.5-37.9179.7179.562.6000113A537 R755 R756A537-L752 HydrophobicContact CB-CD2 4.21Å; L752-R755 PolarHBondContact O-N 3.45Å; L752-R756 HydrophobicContact CD1-CG 4.31Å; L752-R756 WeakPolarHBondContact O-CG 3.34Å; L752-R756 PolarHBondContact O-N 2.73Å
753A95.9Very high94.4Very high8 Ų841 Ų417%0.06621%0.214CC..Hα-helixtrans-68.3-48-174.600000111.8V534 Q535 Y735 N751 R756 G757V534-A753 HydrophobicContact CG1-CB 4.04Å; Q535-A753 PolarHBondContact N-O 3.22Å; Q535-A753 WeakPolarHBondContact O-CA 3.34Å; Y735-A753 HydrophobicContact CE1-CB 4.02Å; N751-A753 VanDerWaalsContact C-N 3.3Å; N751-A753 PolarHBondContact O-N 3.38Å; N751-A753 WeakPolarHBondContact OD1-CB 3.47Å; N751-A753 PolarHBondContact OD1-N 3.27Å; A753-R756 PolarHBondContact O-N 3.5Å; A753-G757 PolarHBondContact O-N 3.1Å; A753-G757 VanDerWaalsContact O-N 3.15Å
754L96.9Very high94.6Very high0 Ų038.2 Ų38.20%020%0.198CC..Hα-helixtrans-66.4-37.3175.1-73.9172.4000112.1I529 V534 Y735 L738 L739 L747 L748 N751 R756 G757 L758I529-L754 HydrophobicContact CD1-CD2 4.4Å; I529-L754 HydrophobicContact CG2-CD2 4.24Å; V534-L754 HydrophobicContact CG2-CD2 4.42Å; Y735-L754 HydrophobicContact CD1-CD1 4.34Å; Y735-L754 HydrophobicContact CD1-CD2 3.65Å; Y735-L754 HydrophobicContact CD1-CG 3.8Å; Y735-L754 HydrophobicContact CE1-CG 4.45Å; Y735-L754 HydrophobicContact CG-CD2 4.31Å; L738-L754 HydrophobicContact CB-CD1 4.21Å; L738-L754 HydrophobicContact CD1-CD1 4.32Å; L739-L754 HydrophobicContact CD1-CD2 4.26Å; L739-L754 HydrophobicContact CD2-CD1 4.18Å; L739-L754 HydrophobicContact CD2-CD2 4.4Å; L739-L754 HydrophobicContact CG-CD1 4.29Å; L739-L754 HydrophobicContact CG-CD2 4.39Å; L747-L754 HydrophobicContact CD1-CD1 4.12Å; L747-L754 HydrophobicContact CD2-CD1 3.56Å; L747-L754 HydrophobicContact CG-CD1 3.83Å; L748-L754 HydrophobicContact CD2-CB 4.12Å; N751-L754 HydrophobicContact CB-CB 4.34Å; N751-L754 HydrophobicContact CB-CD1 4.39Å; N751-L754 PolarHBondContact OD1-N 3.46Å; L754-R756 VanDerWaalsContact C-N 3.31Å; L754-R756 PolarHBondContact O-N 2.91Å; L754-G757 CarbonylContact O-C 3.54Å; L754-G757 WeakPolarHBondContact O-CA 3.24Å; L754-G757 PolarHBondContact O-N 3.4Å; L754-L758 PolarHBondContact O-N 3.02Å; L754-L758 VanDerWaalsContact O-N 3.08Å
755R95.9Very high94.9Very high59 Ų5937 Ų3722%0.22319%0.191CC..Hα-helixtrans-58.6-42175.2-167.3-172.9-45.4166.916.5112.6L748 K749 N751 L752 G757 L758 V781L748-R755 VanDerWaalsContact O-CZ 3.24Å; L748-R755 PolarHBondContact O-NE 3.12Å; L748-R755 PolarHBondContact O-NH2 3.14Å; L748-R755 VanDerWaalsContact O-NH2 3.07Å; K749-R755 PolarHBondContact O-NH2 2.89Å; N751-R755 VanDerWaalsContact O-CB 3.32Å; N751-R755 WeakPolarHBondContact O-CB 3.38Å; N751-R755 PolarHBondContact O-N 3.18Å; L752-R755 PolarHBondContact O-N 3.45Å; R755-G757 VanDerWaalsContact C-N 3.28Å; R755-L758 WeakPolarHBondContact O-CB 3.48Å; R755-L758 PolarHBondContact O-N 3.36Å; R755-V781 HydrophobicContact CG-CB 4.25Å; R755-V781 HydrophobicContact CG-CG1 3.62Å; R755-V781 HydrophobicContact CG-CG2 4.45Å
756R94.8Very high95Very high86 Ų8634.7 Ų34.733%0.32518%0.18SC..Hα-helixtrans-70.4-25.8175.1-75.1172.8169.1-170.1-6.7112.7N533 Q535 P536 N539 L752 A753 L754 I767N533-R756 CarbonylContact O-C 3.59Å; Q535-R756 HydrophobicContact CB-CB 4.34Å; Q535-R756 WeakPolarHBondContact O-CD 3.49Å; P536-R756 PolarHBondContact O-NH1 3.41Å; N539-R756 PolarHBondContact OD1-NH1 3.01Å; N539-R756 VanDerWaalsContact OD1-NH1 3.14Å; L752-R756 HydrophobicContact CD1-CG 4.31Å; L752-R756 WeakPolarHBondContact O-CG 3.34Å; L752-R756 PolarHBondContact O-N 2.73Å; A753-R756 PolarHBondContact O-N 3.5Å; L754-R756 VanDerWaalsContact C-N 3.31Å; L754-R756 PolarHBondContact O-N 2.91Å; R756-I767 WeakPolarHBondContact O-CD1 3.38Å
757G95.7Very high95.2Very high0 Ų032.9 Ų32.90%017%0.165CC..Hα-helixtrans-74.8-21.9173.800000114.5I529 A530 N533 A753 L754 R755 N759I529-G757 WeakPolarHBondContact CA-O 3.46Å; A530-G757 PolarHBondContact N-O 3.35Å; N533-G757 PolarHBondContact O-N 2.87Å; A753-G757 PolarHBondContact O-N 3.1Å; A753-G757 VanDerWaalsContact O-N 3.15Å; L754-G757 CarbonylContact O-C 3.54Å; L754-G757 WeakPolarHBondContact O-CA 3.24Å; L754-G757 PolarHBondContact O-N 3.4Å; R755-G757 VanDerWaalsContact C-N 3.28Å; G757-N759 PolarHBondContact O-N 2.9Å; G757-N759 PolarHBondContact O-ND2 3.35Å
758L97Very high95.2Very high0 Ų037.5 Ų37.50%019%0.186CC..EExtended strand (participates in β ladder)trans-63117.3-178.7-171.871.7000110.5I529 L748 L754 R755 T766 I767 V781I529-L758 HydrophobicContact CG1-CD1 4.02Å; L748-L758 HydrophobicContact CD1-CD1 4.1Å; L748-L758 HydrophobicContact CD1-CD2 4.01Å; L748-L758 HydrophobicContact CD2-CB 4.46Å; L754-L758 PolarHBondContact O-N 3.02Å; L754-L758 VanDerWaalsContact O-N 3.08Å; R755-L758 WeakPolarHBondContact O-CB 3.48Å; R755-L758 PolarHBondContact O-N 3.36Å; L758-T766 HydrophobicContact CD2-CG2 4.36Å; L758-T766 PolarHBondContact O-OG1 2.6Å; L758-I767 WeakPolarHBondContact O-CD1 3.44Å; L758-V781 HydrophobicContact CD2-CG1 3.8Å; L758-V781 HydrophobicContact CD2-CG2 4.44Å
759N96.8Very high95.1Very high1 Ų138.1 Ų38.11%0.00519%0.191CC..EExtended strand (participates in β ladder)trans-102.6-46.8-178-94.3-112.4000112.1L509 L511 S528 A530 N533 G757 L765 T766 I767L509-N759 HydrophobicContact CD1-CB 3.85Å; L511-N759 HydrophobicContact CD1-CB 3.88Å; L511-N759 WeakPolarHBondContact CD1-OD1 3.42Å; S528-N759 PolarHBondContact O-N 2.82Å; A530-N759 WeakPolarHBondContact CB-ND2 3.43Å; N533-N759 PolarHBondContact OD1-ND2 2.87Å; G757-N759 PolarHBondContact O-N 2.9Å; G757-N759 PolarHBondContact O-ND2 3.35Å; N759-L765 WeakPolarHBondContact O-CD1 3.39Å; N759-T766 WeakPolarHBondContact CA-OG1 3.24Å; N759-T766 PolarHBondContact O-N 3.39Å; N759-T766 PolarHBondContact O-OG1 2.82Å; N759-I767 HydrophobicContact CB-CG1 4.44Å
760T97.2Very high95.2Very high0 Ų032.8 Ų32.80%017%0.168CC..EExtended strand (participates in β ladder)trans-130.414317667.10000111.4L511 L521 L522 V526 H527 S528 K764L511-T760 HydrophobicContact CD1-CG2 4.31Å; L521-T760 HydrophobicContact CB-CG2 3.99Å; L521-T760 HydrophobicContact CD1-CG2 4.4Å; L522-T760 HydrophobicContact CD2-CG2 3.88Å; L522-T760 HydrophobicContact CG-CG2 4.4Å; V526-T760 CarbonylContact O-C 3.04Å; V526-T760 PolarHBondContact O-OG1 2.96Å; H527-T760 CarbonylContact C-O 3.43Å; H527-T760 WeakPolarHBondContact CA-O 3.38Å; S528-T760 WeakPolarHBondContact CB-OG1 3.35Å; S528-T760 PolarHBondContact N-O 3.1Å; S528-T760 PolarHBondContact N-OG1 2.83Å; S528-T760 PolarHBondContact O-N 3.42Å; S528-T760 WeakPolarHBondContact OG-CB 3.47Å; S528-T760 PolarHBondContact OG-N 3.46Å; S528-T760 PolarHBondContact OG-OG1 3.49Å; T760-K764 CarbonylContact C-O 3.47Å; T760-K764 VanDerWaalsContact CA-O 3.24Å; T760-K764 WeakPolarHBondContact CA-O 3.5Å
761Y95.7Very high95.3Very high10 Ų1026.3 Ų26.34%0.03913%0.134CC..EExtended strand (participates in β ladder)trans-149.9122.1175.6-175.4-93.7000109.9H527 L744 I745 G763 K764 A784 L785H527-Y761 HydrophobicContact CB-CD2 4.48Å; H527-Y761 AromaticContact CD2-CD2 3.81Å; H527-Y761 AromaticContact CE1-CE2 3.73Å; H527-Y761 AromaticContact CG-CD2 3.85Å; H527-Y761 AromaticContact ND1-CE2 3.83Å; H527-Y761 AromaticContact NE2-CE2 3.9Å; L744-Y761 HydrophobicContact CD2-CE2 4.45Å; I745-Y761 WeakPolarHBondContact CD1-OH 3.29Å; I745-Y761 WeakPolarHBondContact CG1-OH 3.41Å; Y761-G763 PolarHBondContact O-N 2.91Å; Y761-G763 VanDerWaalsContact O-N 3.1Å; Y761-K764 PolarHBondContact N-O 3.15Å; Y761-K764 WeakPolarHBondContact O-CB 3.39Å; Y761-K764 PolarHBondContact O-N 3.32Å; Y761-A784 HydrophobicContact CD1-CB 4.28Å; Y761-A784 VanDerWaalsContact CD1-O 3.31Å; Y761-A784 WeakPolarHBondContact CD1-O 3.31Å; Y761-A784 VanDerWaalsContact CE1-O 3.3Å; Y761-A784 WeakPolarHBondContact CE1-O 3.21Å; Y761-L785 HydrophobicContact CD1-CD2 4.26Å; Y761-L785 HydrophobicContact CD2-CD2 4.09Å; Y761-L785 HydrophobicContact CE1-CD2 3.98Å; Y761-L785 HydrophobicContact CE2-CD2 3.79Å; Y761-L785 HydrophobicContact CG-CD2 4.31Å
762N93.4Very high95.3Very high56 Ų5629.9 Ų29.930%0.29915%0.152SC..THydrogen-bonded Turntrans45.844180-76.3-15.4000113.8H527 K764H527-N762 PolarHBondContact NE2-OD1 3.38Å; N762-K764 VanDerWaalsContact C-N 3.31Å; N762-K764 PolarHBondContact O-N 3.01Å
763G94.9Very high95.1Very high30 Ų3029.7 Ų29.731%0.30915%0.152SC..THydrogen-bonded Turntrans77.411178.100000115.6L522 Y761L522-G763 WeakPolarHBondContact CD2-O 3.41Å; L522-G763 WeakPolarHBondContact O-CA 3.41Å; Y761-G763 PolarHBondContact O-N 2.91Å; Y761-G763 VanDerWaalsContact O-N 3.1Å
764K95.8Very high95Very high36 Ų3630 Ų3016%0.15715%0.152CC..EExtended strand (participates in β ladder)trans-106.1141.5175.1-61.5174.4178.6175.60111.1T760 Y761 N762 F779 T783 A784T760-K764 CarbonylContact C-O 3.47Å; T760-K764 VanDerWaalsContact CA-O 3.24Å; T760-K764 WeakPolarHBondContact CA-O 3.5Å; Y761-K764 PolarHBondContact N-O 3.15Å; Y761-K764 WeakPolarHBondContact O-CB 3.39Å; Y761-K764 PolarHBondContact O-N 3.32Å; N762-K764 VanDerWaalsContact C-N 3.31Å; N762-K764 PolarHBondContact O-N 3.01Å; K764-F779 HydrophobicContact CB-CB 3.98Å; K764-F779 HydrophobicContact CB-CD2 3.71Å; K764-F779 HydrophobicContact CB-CE2 4.36Å; K764-F779 HydrophobicContact CB-CG 3.87Å; K764-F779 HydrophobicContact CD-CB 4.22Å; K764-F779 HydrophobicContact CD-CD1 4.1Å; K764-F779 HydrophobicContact CD-CG 4.04Å; K764-F779 HydrophobicContact CG-CB 4.41Å; K764-F779 HydrophobicContact CG-CD1 4.27Å; K764-F779 HydrophobicContact CG-CD2 3.97Å; K764-F779 HydrophobicContact CG-CE2 4.27Å; K764-F779 HydrophobicContact CG-CG 3.95Å; K764-T783 PolarHBondContact NZ-O 2.94Å; K764-A784 HydrophobicContact CB-CB 4.42Å; K764-A784 HydrophobicContact CD-CB 3.9Å
765L97Very high94.9Very high2 Ų236.7 Ų36.71%0.0119%0.188CC..EExtended strand (participates in β ladder)trans-93.7123.1174.6179.763.3000109.8L511 T518 L522 N759 V770 A771 L776 F779L511-L765 HydrophobicContact CD1-CD1 4.33Å; T518-L765 HydrophobicContact CG2-CD1 4.17Å; T518-L765 HydrophobicContact CG2-CD2 4.36Å; L522-L765 HydrophobicContact CD1-CB 4.4Å; L522-L765 HydrophobicContact CD2-CB 4.01Å; N759-L765 WeakPolarHBondContact O-CD1 3.39Å; L765-V770 HydrophobicContact CD1-CB 4.46Å; L765-V770 HydrophobicContact CD1-CG1 3.99Å; L765-V770 HydrophobicContact CD2-CG1 4.13Å; L765-A771 HydrophobicContact CD2-CB 3.71Å; L765-A771 HydrophobicContact CG-CB 4.41Å; L765-L776 HydrophobicContact CD2-CB 3.99Å; L765-L776 HydrophobicContact CD2-CD1 4.22Å; L765-F779 PolarHBondContact O-N 2.91Å
766T96.2Very high94.9Very high6 Ų635.5 Ų35.54%0.03719%0.186CC..  trans-1101.1-169.150.60000115.1L758 N759 Y778 F779 V781 A784L758-T766 HydrophobicContact CD2-CG2 4.36Å; L758-T766 PolarHBondContact O-OG1 2.6Å; N759-T766 WeakPolarHBondContact CA-OG1 3.24Å; N759-T766 PolarHBondContact O-N 3.39Å; N759-T766 PolarHBondContact O-OG1 2.82Å; T766-Y778 WeakPolarHBondContact O-CE2 3.22Å; T766-F779 WeakPolarHBondContact CA-O 3.41Å; T766-V781 HydrophobicContact CG2-CG2 4.23Å; T766-A784 HydrophobicContact CG2-CB 3.75Å
767I94.9Very high94.9Very high24 Ų2435.7 Ų35.712%0.12320%0.198CC..  trans-104.8114.2173.2-56-62.3000109.6R756 L758 N759 A769 V770 A771R756-I767 WeakPolarHBondContact O-CD1 3.38Å; L758-I767 WeakPolarHBondContact O-CD1 3.44Å; N759-I767 HydrophobicContact CB-CG1 4.44Å; I767-A769 HydrophobicContact CG2-CB 4.23Å; I767-A769 PolarHBondContact O-N 2.96Å; I767-V770 HydrophobicContact CB-CB 4.1Å; I767-V770 HydrophobicContact CB-CG2 3.89Å; I767-V770 HydrophobicContact CG2-CB 4.13Å; I767-V770 HydrophobicContact CG2-CG2 3.64Å; I767-V770 PolarHBondContact O-N 3.39Å; I767-A771 PolarHBondContact O-N 2.97Å; I767-A771 VanDerWaalsContact O-N 3.08Å
768E94.7Very high94.9Very high112 Ų11240.1 Ų40.152%0.52322%0.215SC..Hα-helixtrans-59.7-44.7-178.7-176.3173.4-154.700112.4V770 A771 I772 Y778E768-V770 VanDerWaalsContact C-N 3.35Å; E768-V770 PolarHBondContact O-N 3.24Å; E768-A771 WeakPolarHBondContact O-CB 3.22Å; E768-A771 PolarHBondContact O-N 3.42Å; E768-A771 VanDerWaalsContact O-N 3.14Å; E768-I772 HydrophobicContact CG-CD1 3.95Å; E768-I772 WeakPolarHBondContact O-CG1 3.5Å; E768-I772 PolarHBondContact O-N 2.9Å; E768-Y778 HydrophobicContact CB-CD1 4.22Å; E768-Y778 HydrophobicContact CB-CD2 4.04Å; E768-Y778 HydrophobicContact CB-CE1 4.06Å; E768-Y778 HydrophobicContact CB-CE2 3.91Å; E768-Y778 HydrophobicContact CB-CG 4.21Å; E768-Y778 HydrophobicContact CG-CD1 4.15Å; E768-Y778 HydrophobicContact CG-CE1 4.21Å; E768-Y778 HydrophobicContact CG-CG 4.41Å
769A91.8Very high94.9Very high13 Ų1343.6 Ų43.611%0.10723%0.231CC..Hα-helixtrans-58.6-44179.400000112.7G657 H658 I767 I772 D773G657-A769 WeakPolarHBondContact O-CB 3.38Å; H658-A769 VanDerWaalsContact CE1-CB 3.42Å; H658-A769 WeakPolarHBondContact CE1-CB 3.5Å; H658-A769 WeakPolarHBondContact NE2-CB 3.35Å; I767-A769 HydrophobicContact CG2-CB 4.23Å; I767-A769 PolarHBondContact O-N 2.96Å; A769-I772 PolarHBondContact O-N 3.18Å; A769-D773 WeakPolarHBondContact O-CB 3.41Å; A769-D773 PolarHBondContact O-N 3.43Å
770V93.5Very high94.7Very high3 Ų346.3 Ų46.32%0.01825%0.248CC..Hα-helixtrans-65.3-40.6176.4175.40000110.9L511 A512 L765 I767 E768 I772 D773 L774L511-V770 HydrophobicContact CB-CG1 3.59Å; L511-V770 HydrophobicContact CB-CG2 4.17Å; A512-V770 HydrophobicContact CB-CG2 4.2Å; L765-V770 HydrophobicContact CD1-CB 4.46Å; L765-V770 HydrophobicContact CD1-CG1 3.99Å; L765-V770 HydrophobicContact CD2-CG1 4.13Å; I767-V770 HydrophobicContact CB-CB 4.1Å; I767-V770 HydrophobicContact CB-CG2 3.89Å; I767-V770 HydrophobicContact CG2-CB 4.13Å; I767-V770 HydrophobicContact CG2-CG2 3.64Å; I767-V770 PolarHBondContact O-N 3.39Å; E768-V770 VanDerWaalsContact C-N 3.35Å; E768-V770 PolarHBondContact O-N 3.24Å; V770-I772 VanDerWaalsContact C-N 3.33Å; V770-I772 PolarHBondContact O-N 3.43Å; V770-D773 PolarHBondContact O-N 3.14Å; V770-L774 HydrophobicContact CG1-CD1 3.84Å; V770-L774 HydrophobicContact CG1-CG 4.26Å; V770-L774 VanDerWaalsContact O-CB 3.27Å; V770-L774 WeakPolarHBondContact O-CB 3.45Å; V770-L774 WeakPolarHBondContact O-CG 3.44Å; V770-L774 PolarHBondContact O-N 3.01Å
771A94.6Very high94.4Very high5 Ų547.3 Ų47.34%0.04125%0.254CS..Hα-helixtrans-62.8-41178.300000111.9L765 I767 E768 D775 L776L765-A771 HydrophobicContact CD2-CB 3.71Å; L765-A771 HydrophobicContact CG-CB 4.41Å; I767-A771 PolarHBondContact O-N 2.97Å; I767-A771 VanDerWaalsContact O-N 3.08Å; E768-A771 WeakPolarHBondContact O-CB 3.22Å; E768-A771 PolarHBondContact O-N 3.42Å; E768-A771 VanDerWaalsContact O-N 3.14Å; A771-D775 WeakPolarHBondContact O-CA 3.39Å; A771-D775 PolarHBondContact O-N 3.3Å; A771-L776 WeakPolarHBondContact CB-O 3.09Å; A771-L776 PolarHBondContact O-N 3.45Å
772I93.6Very high94.1Very high111 Ų11151.2 Ų51.257%0.56928%0.276SS*.Hα-helixtrans-64.8-52.9174.8-67.7166.6000110.6E768 A769 V770 L774 D775E768-I772 HydrophobicContact CG-CD1 3.95Å; E768-I772 WeakPolarHBondContact O-CG1 3.5Å; E768-I772 PolarHBondContact O-N 2.9Å; A769-I772 PolarHBondContact O-N 3.18Å; V770-I772 VanDerWaalsContact C-N 3.33Å; V770-I772 PolarHBondContact O-N 3.43Å; I772-L774 PolarHBondContact O-N 2.89Å; I772-D775 PolarHBondContact O-N 2.93Å
773D91.1Very high93.8Very high62 Ų6252 Ų5233%0.33228%0.283SS..Hα-helixtrans-63.7-29.2-175.4-75.2-2.4000112.6A512 H658 R659 A769 V770A512-D773 HydrophobicContact CB-CB 4.37Å; H658-D773 VanDerWaalsContact CA-OD2 3.28Å; H658-D773 WeakPolarHBondContact CA-OD2 3.38Å; H658-D773 IonicContact ND1-OD1 2.73Å; H658-D773 IonicContact ND1-OD2 3.83Å; R659-D773 PolarHBondContact N-OD2 3.28Å; A769-D773 WeakPolarHBondContact O-CB 3.41Å; A769-D773 PolarHBondContact O-N 3.43Å; V770-D773 PolarHBondContact O-N 3.14Å
774L93.8Very high93.4Very high14 Ų1450.6 Ų50.67%0.07327%0.268CS..Hα-helixtrans-99.9-4.2-179.3-63.9-171000115.1L511 A512 K515 T518 V770 I772 L776L511-L774 WeakPolarHBondContact O-CD1 3.2Å; A512-L774 WeakPolarHBondContact O-CD2 3.5Å; K515-L774 HydrophobicContact CB-CD1 4.45Å; K515-L774 HydrophobicContact CB-CD2 3.94Å; K515-L774 VanDerWaalsContact CE-O 3.27Å; K515-L774 WeakPolarHBondContact CE-O 3.45Å; K515-L774 HydrophobicContact CG-CD2 4.42Å; K515-L774 PolarHBondContact NZ-O 3.35Å; T518-L774 HydrophobicContact CG2-CD1 3.88Å; T518-L774 VanDerWaalsContact OG1-CD1 3.3Å; T518-L774 WeakPolarHBondContact OG1-CD1 3.45Å; V770-L774 HydrophobicContact CG1-CD1 3.84Å; V770-L774 HydrophobicContact CG1-CG 4.26Å; V770-L774 VanDerWaalsContact O-CB 3.27Å; V770-L774 WeakPolarHBondContact O-CB 3.45Å; V770-L774 WeakPolarHBondContact O-CG 3.44Å; V770-L774 PolarHBondContact O-N 3.01Å; I772-L774 PolarHBondContact O-N 2.89Å; L774-L776 HydrophobicContact CB-CD1 3.88Å; L774-L776 HydrophobicContact CB-CG 4.02Å; L774-L776 HydrophobicContact CD1-CD1 3.95Å
775D95Very high92.9Very high140 Ų14049.6 Ų49.675%0.74926%0.264SS*.THydrogen-bonded Turntrans53.161.4-172.5-173.139.7000111.4A771 I772A771-D775 WeakPolarHBondContact O-CA 3.39Å; A771-D775 PolarHBondContact O-N 3.3Å; I772-D775 PolarHBondContact O-N 2.93Å
776L95.5Very high91.9Very high35 Ų3557.2 Ų57.218%0.18330%0.3CS..  trans-131.3157.2-179.7-69.4176.2000111.4T518 L522 L765 A771 L774 Y778T518-L776 HydrophobicContact CG2-CD1 3.65Å; L522-L776 HydrophobicContact CD1-CD1 4.45Å; L765-L776 HydrophobicContact CD2-CB 3.99Å; L765-L776 HydrophobicContact CD2-CD1 4.22Å; A771-L776 WeakPolarHBondContact CB-O 3.09Å; A771-L776 PolarHBondContact O-N 3.45Å; L774-L776 HydrophobicContact CB-CD1 3.88Å; L774-L776 HydrophobicContact CB-CG 4.02Å; L774-L776 HydrophobicContact CD1-CD1 3.95Å; L776-Y778 PolarHBondContact O-N 3.23Å
777P94.7Very high90.2Very high89 Ų8961.5 Ų61.558%0.57834%0.336SS*.  trans-65.9128.9177.1-20.933.3000112.9F779P777-F779 HydrophobicContact CB-CE2 3.81Å; P777-F779 HydrophobicContact CB-CZ 4.23Å
778Y96Very high89.9Confident93 Ų9363.4 Ų63.437%0.36535%0.346SS..BIsolated β-bridgetrans-91.7137.8173.6168.7-124.6000111.6T766 E768 L776 P780T766-Y778 WeakPolarHBondContact O-CE2 3.22Å; E768-Y778 HydrophobicContact CB-CD1 4.22Å; E768-Y778 HydrophobicContact CB-CD2 4.04Å; E768-Y778 HydrophobicContact CB-CE1 4.06Å; E768-Y778 HydrophobicContact CB-CE2 3.91Å; E768-Y778 HydrophobicContact CB-CG 4.21Å; E768-Y778 HydrophobicContact CG-CD1 4.15Å; E768-Y778 HydrophobicContact CG-CE1 4.21Å; E768-Y778 HydrophobicContact CG-CG 4.41Å; L776-Y778 PolarHBondContact O-N 3.23Å; Y778-P780 HydrophobicContact CE1-CG 4.09Å
779F95.9Very high89.7Confident74 Ų7460.8 Ų60.833%0.32534%0.337SS..  trans-126120.7173.1-63-90.8000110.4K764 L765 T766 P777 V781K764-F779 HydrophobicContact CB-CB 3.98Å; K764-F779 HydrophobicContact CB-CD2 3.71Å; K764-F779 HydrophobicContact CB-CE2 4.36Å; K764-F779 HydrophobicContact CB-CG 3.87Å; K764-F779 HydrophobicContact CD-CB 4.22Å; K764-F779 HydrophobicContact CD-CD1 4.1Å; K764-F779 HydrophobicContact CD-CG 4.04Å; K764-F779 HydrophobicContact CG-CB 4.41Å; K764-F779 HydrophobicContact CG-CD1 4.27Å; K764-F779 HydrophobicContact CG-CD2 3.97Å; K764-F779 HydrophobicContact CG-CE2 4.27Å; K764-F779 HydrophobicContact CG-CG 3.95Å; L765-F779 PolarHBondContact O-N 2.91Å; T766-F779 WeakPolarHBondContact CA-O 3.41Å; P777-F779 HydrophobicContact CB-CE2 3.81Å; P777-F779 HydrophobicContact CB-CZ 4.23Å; F779-V781 PolarHBondContact O-N 2.96Å
780P93.6Very high89.6Confident57 Ų5763.4 Ų63.437%0.3735%0.35SS..  trans-55.9138.3172.9-25.434.5000111.5Y778 N782 T783 A784Y778-P780 HydrophobicContact CE1-CG 4.09Å; P780-N782 VanDerWaalsContact C-N 3.28Å; P780-N782 PolarHBondContact O-N 3.17Å; P780-T783 WeakPolarHBondContact O-CB 3.44Å; P780-T783 PolarHBondContact O-N 3.07Å; P780-A784 PolarHBondContact O-N 3.05Å
781V91.7Very high89.3Confident21 Ų2167 Ų6713%0.12737%0.369CS..Hα-helixtrans-52.2-44.7-175.51760000112.3R755 L758 T766 F779 T783 A784 L785R755-V781 HydrophobicContact CG-CB 4.25Å; R755-V781 HydrophobicContact CG-CG1 3.62Å; R755-V781 HydrophobicContact CG-CG2 4.45Å; L758-V781 HydrophobicContact CD2-CG1 3.8Å; L758-V781 HydrophobicContact CD2-CG2 4.44Å; T766-V781 HydrophobicContact CG2-CG2 4.23Å; F779-V781 PolarHBondContact O-N 2.96Å; V781-T783 VanDerWaalsContact C-N 3.3Å; V781-T783 PolarHBondContact O-N 3.27Å; V781-A784 WeakPolarHBondContact O-CA 3.12Å; V781-A784 WeakPolarHBondContact O-CB 3.49Å; V781-A784 PolarHBondContact O-N 3.37Å; V781-L785 HydrophobicContact CG1-CD1 3.86Å; V781-L785 HydrophobicContact CG1-CG 4.18Å; V781-L785 WeakPolarHBondContact O-CG 3.21Å; V781-L785 PolarHBondContact O-N 3.21Å
782N87.8Confident89Confident93 Ų9370.9 Ų70.950%0.49739%0.39SS..Hα-helixtrans-60-41.1-179.8-64.7-13.5000111.9P780 A784 L785 E786P780-N782 VanDerWaalsContact C-N 3.28Å; P780-N782 PolarHBondContact O-N 3.17Å; N782-A784 VanDerWaalsContact C-N 3.33Å; N782-L785 PolarHBondContact O-N 2.87Å; N782-E786 WeakPolarHBondContact O-CG 3.38Å; N782-E786 PolarHBondContact O-N 3.1Å
783T88Confident88.7Confident73 Ų7368.2 Ų68.245%0.44838%0.378SS..Hα-helixtrans-71.9-27.2175.7-48.80000112.5K764 P780 V781K764-T783 PolarHBondContact NZ-O 2.94Å; P780-T783 WeakPolarHBondContact O-CB 3.44Å; P780-T783 PolarHBondContact O-N 3.07Å; V781-T783 VanDerWaalsContact C-N 3.3Å; V781-T783 PolarHBondContact O-N 3.27Å
784A85.4Confident88.5Confident0 Ų068.6 Ų68.60%038%0.381CS..Hα-helixtrans-70.3-39.2174.400000111.7Y761 K764 T766 P780 V781 N782Y761-A784 HydrophobicContact CD1-CB 4.28Å; Y761-A784 VanDerWaalsContact CD1-O 3.31Å; Y761-A784 WeakPolarHBondContact CD1-O 3.31Å; Y761-A784 VanDerWaalsContact CE1-O 3.3Å; Y761-A784 WeakPolarHBondContact CE1-O 3.21Å; K764-A784 HydrophobicContact CB-CB 4.42Å; K764-A784 HydrophobicContact CD-CB 3.9Å; T766-A784 HydrophobicContact CG2-CB 3.75Å; P780-A784 PolarHBondContact O-N 3.05Å; V781-A784 WeakPolarHBondContact O-CA 3.12Å; V781-A784 WeakPolarHBondContact O-CB 3.49Å; V781-A784 PolarHBondContact O-N 3.37Å; N782-A784 VanDerWaalsContact C-N 3.33Å
785L86.4Confident88.1Confident14 Ų1472.8 Ų72.87%0.07341%0.405CS..Hα-helixtrans-77.1-18.4-178.3-65.1175.8000114.6L748 Y761 V781 N782L748-L785 HydrophobicContact CB-CD1 4.06Å; L748-L785 HydrophobicContact CD1-CD2 3.97Å; Y761-L785 HydrophobicContact CD1-CD2 4.26Å; Y761-L785 HydrophobicContact CD2-CD2 4.09Å; Y761-L785 HydrophobicContact CE1-CD2 3.98Å; Y761-L785 HydrophobicContact CE2-CD2 3.79Å; Y761-L785 HydrophobicContact CG-CD2 4.31Å; V781-L785 HydrophobicContact CG1-CD1 3.86Å; V781-L785 HydrophobicContact CG1-CG 4.18Å; V781-L785 WeakPolarHBondContact O-CG 3.21Å; V781-L785 PolarHBondContact O-N 3.21Å; N782-L785 PolarHBondContact O-N 2.87Å
786E75.9Confident87.6Confident162 Ų16267.3 Ų67.376%0.75738%0.376SS*.THydrogen-bonded Turntrans-89.9-5.8-177.8-75.6173.6179.300114.6N782N782-E786 WeakPolarHBondContact O-CG 3.38Å; N782-E786 PolarHBondContact O-N 3.1Å
787A60Low86.8Confident96 Ų9670.2 Ų70.279%0.79339%0.394SS*.  trans-120.80-173.100000111.7

Retrieved 787 of 787 residues in 1627 ms (Link to these results)