A0A077ZAC8_TRITR Loading...

Uncharacterized protein

AlphaFold DB , UniProt , Accession A0A077ZAC8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 628 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.2	Very low	31.2	Very low	239 Å²	239	148.4 Å²	148.4	100%	1.177	87%	0.867	S	S	*	*				0	118.2	0	-89.6	173.4	173.4	0	0	108
2	L	33.2	Very low	31.5	Very low	158 Å²	158	147.5 Å²	147.5	83%	0.827	87%	0.865	S	S	*	*			trans	55.1	87	160.7	-65.6	151.8	0	0	0	117
3	T	30.4	Very low	31.3	Very low	121 Å²	121	140.8 Å²	140.8	74%	0.742	85%	0.846	S	S	*	*				46.6	110.1	77.9	67.5	0	0	0	0	116
4	T	35.6	Very low	31.2	Very low	131 Å²	131	143.7 Å²	143.7	80%	0.804	84%	0.837	S	S	*	*			trans	-173.4	91.9	141.1	33.1	0	0	0	0	108.3
5	T	32.4	Very low	31.2	Very low	127 Å²	127	143.7 Å²	143.7	78%	0.779	82%	0.823	S	S	*	*				72.1	115	103.9	49.6	0	0	0	0	115.9
6	P	30.2	Very low	31.7	Very low	137 Å²	137	141.8 Å²	141.8	89%	0.89	80%	0.802	S	S	*	*			trans	-91.9	120.6	174.1	34.7	-26.7	0	0	0	110.7
7	A	30.2	Very low	31.6	Very low	101 Å²	101	142.2 Å²	142.2	84%	0.835	80%	0.796	S	S	*	*			trans	-152.4	78.8	170.5	0	0	0	0	0	110
8	A	29.4	Very low	32	Very low	99 Å²	99	138 Å²	138	82%	0.818	77%	0.771	S	S	*	*			trans	-172.3	50.2	166.9	0	0	0	0	0	113.6
9	I	28.5	Very low	32.2	Very low	167 Å²	167	135.3 Å²	135.3	86%	0.856	76%	0.76	S	S	*	*			trans	-148	91.4	167.9	-51.9	177.8	0	0	0	109.6
10	M	28.9	Very low	32.3	Very low	181 Å²	181	134.2 Å²	134.2	89%	0.892	75%	0.753	S	S	*	*			trans	-169.4	61.3	155.4	-108.1	-173.8	-147.2	0	0	109.7
11	D	30.2	Very low	32.6	Very low	171 Å²	171	132.2 Å²	132.2	91%	0.914	75%	0.747	S	S	*	*			trans	-128.4	82.4	161.9	-101.7	-24	0	0	0	107
12	T	34.8	Very low	33	Very low	138 Å²	138	124.1 Å²	124.1	85%	0.847	71%	0.712	S	S	*	*			trans	-117.8	95.8	165	45.5	0	0	0	0	107.6
13	G	28.5	Very low	33.2	Very low	60 Å²	60	122.9 Å²	122.9	62%	0.619	70%	0.696	S	S	*	*			trans	-74.5	138.3	177.4	0	0	0	0	0	112.1
14	Y	29.9	Very low	33.8	Very low	182 Å²	182	125.1 Å²	125.1	71%	0.714	70%	0.697	S	S	*	*			trans	-152	73.3	145.2	-75.3	-70.8	0	0	0	107	E587	Y14-E587 WeakPolarHBondContact CE2-OE1 3.39Å
15	F	32.3	Very low	34.6	Very low	143 Å²	143	122.8 Å²	122.8	63%	0.627	68%	0.679	S	S	*	*			trans	-86.6	115.1	163.9	-109.8	-90.1	0	0	0	106.8	E17	F15-E17 PolarHBondContact O-N 2.91Å; F15-E17 VanDerWaalsContact O-N 3.09Å
16	F	38.2	Very low	35.7	Very low	113 Å²	113	119.4 Å²	119.4	50%	0.496	66%	0.661	S	S	.	*			trans	-52	119.5	155.2	-102.2	-93.1	0	0	0	106.3	L18	F16-L18 PolarHBondContact O-N 3.34Å
17	E	30.8	Very low	37.1	Very low	149 Å²	149	118.5 Å²	118.5	70%	0.696	64%	0.643	S	S	*	*			trans	-62.9	90.7	175.1	-67.9	-153.7	118.7	0	0	108.6	F15 R23	F15-E17 PolarHBondContact O-N 2.91Å; F15-E17 VanDerWaalsContact O-N 3.09Å; E17-R23 IonicContact OE1-CZ 2.8Å; E17-R23 IonicContact OE1-NH1 3.76Å; E17-R23 IonicContact OE1-NH2 3.3Å; E17-R23 PolarHBondContact OE1-NH2 3.13Å
18	L	39	Very low	38.8	Very low	67 Å²	67	119.6 Å²	119.6	35%	0.351	64%	0.635	S	S	.	*			trans	-51.3	142	155.6	-83.9	143.2	0	0	0	106.9	F16 N20 V22	F16-L18 PolarHBondContact O-N 3.34Å; L18-N20 PolarHBondContact O-N 3.49Å; L18-V22 HydrophobicContact CB-CB 4.15Å; L18-V22 HydrophobicContact CD1-CG1 4.49Å; L18-V22 HydrophobicContact CD2-CB 4.17Å; L18-V22 HydrophobicContact CD2-CG1 4.18Å; L18-V22 HydrophobicContact CD2-CG2 4.08Å
19	P	36.2	Very low	40.5	Very low	87 Å²	87	119.9 Å²	119.9	57%	0.565	62%	0.617	S	S	*	*			trans	-44.5	134.9	172.9	-24.5	32.2	0	0	0	108.7	S21 V22	P19-S21 PolarHBondContact O-N 2.99Å; P19-V22 PolarHBondContact O-N 3.36Å
20	N	33.9	Very low	42.1	Very low	113 Å²	113	114.2 Å²	114.2	60%	0.604	59%	0.589	S	S	*	*	T	Hydrogen-bonded Turn	trans	-50.6	-17.3	-175.7	-76.6	-28.2	0	0	0	113.6	L18 V22 R23	L18-N20 PolarHBondContact O-N 3.49Å; N20-V22 PolarHBondContact O-N 3.45Å; N20-R23 PolarHBondContact O-N 3.34Å; N20-R23 PolarHBondContact OD1-NH2 3.5Å
21	S	38.2	Very low	44	Very low	92 Å²	92	107.8 Å²	107.8	64%	0.643	56%	0.558	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.7	-29.4	170.9	60	0	0	0	0	115.4	P19	P19-S21 PolarHBondContact O-N 2.99Å
22	V	41.8	Very low	45.9	Very low	70 Å²	70	104.2 Å²	104.2	42%	0.424	54%	0.538	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.1	-22.9	-179.9	-172.4	0	0	0	0	111.9	L18 P19 N20 H24	L18-V22 HydrophobicContact CB-CB 4.15Å; L18-V22 HydrophobicContact CD1-CG1 4.49Å; L18-V22 HydrophobicContact CD2-CB 4.17Å; L18-V22 HydrophobicContact CD2-CG1 4.18Å; L18-V22 HydrophobicContact CD2-CG2 4.08Å; P19-V22 PolarHBondContact O-N 3.36Å; N20-V22 PolarHBondContact O-N 3.45Å; V22-H24 PolarHBondContact O-N 3.24Å; V22-H24 VanDerWaalsContact O-N 3.16Å
23	R	38.2	Very low	47.6	Very low	132 Å²	132	103.1 Å²	103.1	50%	0.498	52%	0.519	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.1	-11.1	177.3	-102.5	-175	-94.5	-168.6	-0.9	113.8	E17 N20	E17-R23 IonicContact OE1-CZ 2.8Å; E17-R23 IonicContact OE1-NH1 3.76Å; E17-R23 IonicContact OE1-NH2 3.3Å; E17-R23 PolarHBondContact OE1-NH2 3.13Å; N20-R23 PolarHBondContact O-N 3.34Å; N20-R23 PolarHBondContact OD1-NH2 3.5Å
24	H	42.4	Very low	49.5	Very low	167 Å²	167	100.3 Å²	100.3	77%	0.773	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.5	-1.7	-177.2	-93.1	-67.6	0	0	0	116.2	V22 S26	V22-H24 PolarHBondContact O-N 3.24Å; V22-H24 VanDerWaalsContact O-N 3.16Å; H24-S26 PolarHBondContact O-N 3.41Å
25	I	52.1	Low	51.7	Low	82 Å²	82	98.9 Å²	98.9	42%	0.421	48%	0.483	S	S	.	.	S	Bend	trans	-79.8	110.9	172	-57.8	178.1	0	0	0	107.8	K27 K29 L30 Y33	I25-K27 PolarHBondContact O-N 3.46Å; I25-K29 HydrophobicContact CG2-CB 3.78Å; I25-L30 HydrophobicContact CG2-CB 4.42Å; I25-Y33 HydrophobicContact CG2-CE2 4.42Å
26	S	55.6	Low	53.7	Low	57 Å²	57	96.5 Å²	96.5	40%	0.399	48%	0.477	S	S	.	.			trans	-58.1	140.2	176.4	72	0	0	0	0	109.8	H24 N28 K29 L30	H24-S26 PolarHBondContact O-N 3.41Å; S26-N28 PolarHBondContact O-N 3.34Å; S26-K29 WeakPolarHBondContact O-CA 3.5Å; S26-K29 WeakPolarHBondContact O-CB 3.38Å; S26-K29 PolarHBondContact O-N 3.4Å; S26-K29 WeakPolarHBondContact OG-CG 3.26Å; S26-L30 PolarHBondContact O-N 3.22Å
27	K	59.7	Low	55.3	Low	118 Å²	118	93.2 Å²	93.2	51%	0.513	46%	0.463	S	S	.	.	H	α-helix	trans	-45.3	-42.5	178	-73.2	176.3	-176.8	164.7	0	112.4	I25 K29 L30 I31 E86 R89	I25-K27 PolarHBondContact O-N 3.46Å; K27-K29 VanDerWaalsContact C-N 3.31Å; K27-K29 PolarHBondContact O-N 3.24Å; K27-L30 PolarHBondContact O-N 3.46Å; K27-I31 WeakPolarHBondContact O-CG1 3.23Å; K27-I31 PolarHBondContact O-N 3.3Å; K27-I31 VanDerWaalsContact O-N 3.12Å; K27-E86 WeakPolarHBondContact CB-OE1 3.46Å; K27-R89 VanDerWaalsContact NZ-NH2 3.2Å
28	N	67	Low	57.3	Low	123 Å²	123	88.1 Å²	88.1	66%	0.658	44%	0.44	S	S	*	.	H	α-helix	trans	-60.1	-36.1	177.4	-62	-3.6	0	0	0	113.1	S26 L32	S26-N28 PolarHBondContact O-N 3.34Å; N28-L32 VanDerWaalsContact O-CB 3.27Å; N28-L32 WeakPolarHBondContact O-CB 3.34Å; N28-L32 PolarHBondContact O-N 3.48Å
29	K	65.1	Low	58.8	Low	105 Å²	105	86.5 Å²	86.5	46%	0.457	44%	0.44	S	S	.	.	H	α-helix	trans	-69.2	-41.3	176.3	-74.7	177.5	-179.4	-173.6	0	111.8	I25 S26 K27 L32 Y33	I25-K29 HydrophobicContact CG2-CB 3.78Å; S26-K29 WeakPolarHBondContact O-CA 3.5Å; S26-K29 WeakPolarHBondContact O-CB 3.38Å; S26-K29 PolarHBondContact O-N 3.4Å; S26-K29 WeakPolarHBondContact OG-CG 3.26Å; K27-K29 VanDerWaalsContact C-N 3.31Å; K27-K29 PolarHBondContact O-N 3.24Å; K29-L32 WeakPolarHBondContact O-CB 3.48Å; K29-L32 PolarHBondContact O-N 3.46Å; K29-Y33 HydrophobicContact CB-CD2 4.49Å; K29-Y33 HydrophobicContact CB-CE2 3.96Å; K29-Y33 WeakPolarHBondContact O-CD2 3.39Å; K29-Y33 PolarHBondContact O-N 2.83Å
30	L	60.7	Low	60.4	Low	48 Å²	48	86.9 Å²	86.9	25%	0.251	44%	0.437	S	S	.	.	H	α-helix	trans	-65.4	-42.6	179.5	-168.3	67.9	0	0	0	111.7	I25 S26 K27 L32 Y33 G34 T82 V85 E86	I25-L30 HydrophobicContact CG2-CB 4.42Å; S26-L30 PolarHBondContact O-N 3.22Å; K27-L30 PolarHBondContact O-N 3.46Å; L30-L32 VanDerWaalsContact C-N 3.35Å; L30-Y33 PolarHBondContact O-N 3.38Å; L30-G34 PolarHBondContact O-N 3.45Å; L30-T82 HydrophobicContact CD1-CG2 3.5Å; L30-T82 VanDerWaalsContact CD1-CG2 3.5Å; L30-T82 HydrophobicContact CG-CG2 3.84Å; L30-V85 HydrophobicContact CD2-CG1 4.28Å; L30-E86 HydrophobicContact CD2-CB 4.13Å
31	I	68.8	Low	62	Low	47 Å²	47	81.5 Å²	81.5	24%	0.241	41%	0.408	C	S	.	.	H	α-helix	trans	-58.5	-48.2	171.8	-66.2	170.8	0	0	0	110.6	K27 Y33 G34 W35 E86	K27-I31 WeakPolarHBondContact O-CG1 3.23Å; K27-I31 PolarHBondContact O-N 3.3Å; K27-I31 VanDerWaalsContact O-N 3.12Å; I31-Y33 PolarHBondContact O-N 3.01Å; I31-G34 PolarHBondContact O-N 2.81Å; I31-W35 VanDerWaalsContact O-CD1 3.29Å; I31-W35 PolarHBondContact O-N 3.27Å; I31-E86 WeakPolarHBondContact CD1-OE1 3.12Å; I31-E86 WeakPolarHBondContact CD1-OE2 3.44Å; I31-E86 VanDerWaalsContact CG1-CD 3.43Å; I31-E86 WeakPolarHBondContact CG1-OE2 3.2Å
32	L	70.8	Confident	63.6	Low	95 Å²	95	79.1 Å²	79.1	50%	0.497	40%	0.395	S	S	.	.	H	α-helix	trans	-59.1	-46.4	180	179.5	65.6	0	0	0	111.2	N28 K29 L30 G34 W35 L36	N28-L32 VanDerWaalsContact O-CB 3.27Å; N28-L32 WeakPolarHBondContact O-CB 3.34Å; N28-L32 PolarHBondContact O-N 3.48Å; K29-L32 WeakPolarHBondContact O-CB 3.48Å; K29-L32 PolarHBondContact O-N 3.46Å; L30-L32 VanDerWaalsContact C-N 3.35Å; L32-G34 VanDerWaalsContact C-N 3.33Å; L32-G34 PolarHBondContact O-N 3.08Å; L32-W35 PolarHBondContact O-N 2.9Å; L32-L36 HydrophobicContact CG-CD1 4.15Å; L32-L36 VanDerWaalsContact O-CG 3.32Å; L32-L36 WeakPolarHBondContact O-CG 3.28Å; L32-L36 PolarHBondContact O-N 2.95Å
33	Y	71.1	Confident	65	Low	116 Å²	116	80.5 Å²	80.5	46%	0.455	40%	0.403	S	S	.	.	H	α-helix	trans	-62	-40.4	175.8	-62.3	-40.4	0	0	0	112.1	I25 K29 L30 I31 W35 L36 M37	I25-Y33 HydrophobicContact CG2-CE2 4.42Å; K29-Y33 HydrophobicContact CB-CD2 4.49Å; K29-Y33 HydrophobicContact CB-CE2 3.96Å; K29-Y33 WeakPolarHBondContact O-CD2 3.39Å; K29-Y33 PolarHBondContact O-N 2.83Å; L30-Y33 PolarHBondContact O-N 3.38Å; I31-Y33 PolarHBondContact O-N 3.01Å; Y33-W35 PolarHBondContact O-N 3.43Å; Y33-L36 HydrophobicContact CD1-CD1 4.33Å; Y33-L36 PolarHBondContact O-N 3.47Å; Y33-M37 WeakPolarHBondContact O-CB 3.45Å; Y33-M37 WeakPolarHBondContact O-CG 3.31Å; Y33-M37 PolarHBondContact O-N 3.43Å
34	G	67.1	Low	66.4	Low	0 Å²	0	75 Å²	75	0%	0	39%	0.385	C	S	.	.	H	α-helix	trans	-57.5	-47.6	173.2	0	0	0	0	0	112.5	L30 I31 L32 M37 I38 G79	L30-G34 PolarHBondContact O-N 3.45Å; I31-G34 PolarHBondContact O-N 2.81Å; L32-G34 VanDerWaalsContact C-N 3.33Å; L32-G34 PolarHBondContact O-N 3.08Å; G34-M37 PolarHBondContact O-N 3.47Å; G34-I38 WeakPolarHBondContact O-CG1 3.3Å; G34-I38 PolarHBondContact O-N 3.01Å; G34-G79 WeakPolarHBondContact O-CA 3.43Å
35	W	77	Confident	67.7	Low	152 Å²	152	68.7 Å²	68.7	58%	0.576	36%	0.357	S	S	*	.	H	α-helix	trans	-65.3	-40.3	176.3	-80	116.1	0	0	0	113.4	I31 L32 Y33 M37 I38 G39 M83	I31-W35 VanDerWaalsContact O-CD1 3.29Å; I31-W35 PolarHBondContact O-N 3.27Å; L32-W35 PolarHBondContact O-N 2.9Å; Y33-W35 PolarHBondContact O-N 3.43Å; W35-M37 VanDerWaalsContact C-N 3.33Å; W35-M37 PolarHBondContact O-N 2.87Å; W35-I38 HydrophobicContact CE3-CD1 4.38Å; W35-I38 PolarHBondContact O-N 3.01Å; W35-G39 PolarHBondContact O-N 3.26Å; W35-M83 HydrophobicContact CD2-CE 4.22Å; W35-M83 HydrophobicContact CD2-SD 4.3Å; W35-M83 HydrophobicContact CZ2-CE 3.78Å
36	L	73.6	Confident	68.5	Low	94 Å²	94	68.9 Å²	68.9	49%	0.492	36%	0.362	S	S	.	.	H	α-helix	trans	-61.6	-42	175.6	-73	171.3	0	0	0	111.3	L32 Y33 G39 N40	L32-L36 HydrophobicContact CG-CD1 4.15Å; L32-L36 VanDerWaalsContact O-CG 3.32Å; L32-L36 WeakPolarHBondContact O-CG 3.28Å; L32-L36 PolarHBondContact O-N 2.95Å; Y33-L36 HydrophobicContact CD1-CD1 4.33Å; Y33-L36 PolarHBondContact O-N 3.47Å; L36-G39 PolarHBondContact O-N 3.17Å; L36-N40 PolarHBondContact O-N 3.11Å
37	M	72.1	Confident	68.9	Low	43 Å²	43	70.4 Å²	70.4	21%	0.212	37%	0.366	C	S	.	.	H	α-helix	trans	-66.1	-39.6	175.8	-72.8	-59	-67	0	0	112.5	Y33 G34 W35 G39 N40 G41 Y75 T78 T104	Y33-M37 WeakPolarHBondContact O-CB 3.45Å; Y33-M37 WeakPolarHBondContact O-CG 3.31Å; Y33-M37 PolarHBondContact O-N 3.43Å; G34-M37 PolarHBondContact O-N 3.47Å; W35-M37 VanDerWaalsContact C-N 3.33Å; W35-M37 PolarHBondContact O-N 2.87Å; M37-G39 VanDerWaalsContact C-N 3.34Å; M37-N40 PolarHBondContact O-N 2.72Å; M37-G41 PolarHBondContact O-N 3.1Å; M37-Y75 HydrophobicContact CE-CD1 4.18Å; M37-Y75 HydrophobicContact CE-CG 4.21Å; M37-T78 HydrophobicContact CE-CG2 4.03Å; M37-T104 HydrophobicContact CE-CG2 3.4Å; M37-T104 VanDerWaalsContact CE-CG2 3.4Å
38	I	73	Confident	69.1	Low	43 Å²	43	64.9 Å²	64.9	22%	0.221	34%	0.342	C	S	.	.	H	α-helix	trans	-62.6	-43.5	172.3	-69.7	170.5	0	0	0	110.4	G34 W35 G41 A42 L76 M83	G34-I38 WeakPolarHBondContact O-CG1 3.3Å; G34-I38 PolarHBondContact O-N 3.01Å; W35-I38 HydrophobicContact CE3-CD1 4.38Å; W35-I38 PolarHBondContact O-N 3.01Å; I38-G41 PolarHBondContact O-N 3.09Å; I38-A42 WeakPolarHBondContact O-CB 3.48Å; I38-A42 PolarHBondContact O-N 3Å; I38-L76 HydrophobicContact CG2-CD2 4.17Å; I38-L76 WeakPolarHBondContact O-CD2 3.3Å; I38-M83 HydrophobicContact CD1-SD 3.53Å; I38-M83 VanDerWaalsContact CD1-SD 3.53Å
39	G	69.5	Low	68.9	Low	33 Å²	33	61.8 Å²	61.8	34%	0.34	33%	0.33	S	S	.	.	H	α-helix	trans	-59.2	-50.1	176	0	0	0	0	0	112.2	W35 L36 M37 G41 A42 V43	W35-G39 PolarHBondContact O-N 3.26Å; L36-G39 PolarHBondContact O-N 3.17Å; M37-G39 VanDerWaalsContact C-N 3.34Å; G39-G41 VanDerWaalsContact C-N 3.34Å; G39-G41 PolarHBondContact O-N 3.05Å; G39-A42 WeakPolarHBondContact O-CB 3.23Å; G39-A42 PolarHBondContact O-N 3.04Å; G39-V43 WeakPolarHBondContact O-CG2 3.17Å; G39-V43 PolarHBondContact O-N 3.14Å
40	N	71.8	Confident	68.7	Low	94 Å²	94	60 Å²	60	50%	0.503	33%	0.327	S	S	.	.	H	α-helix	trans	-61	-42	176.4	-76.5	-17.8	0	0	0	112.2	L36 M37 A42 V43 A44 Y75	L36-N40 PolarHBondContact O-N 3.11Å; M37-N40 PolarHBondContact O-N 2.72Å; N40-A42 VanDerWaalsContact C-N 3.32Å; N40-A42 PolarHBondContact O-N 3.08Å; N40-V43 PolarHBondContact O-N 2.8Å; N40-A44 WeakPolarHBondContact O-CB 3.25Å; N40-A44 PolarHBondContact O-N 3.3Å; N40-Y75 HydrophobicContact CB-CD2 4.31Å
41	G	67.5	Low	68.6	Low	0 Å²	0	57.9 Å²	57.9	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-65.1	-34.1	175.8	0	0	0	0	0	113.4	M37 I38 G39 L45	M37-G41 PolarHBondContact O-N 3.1Å; I38-G41 PolarHBondContact O-N 3.09Å; G39-G41 VanDerWaalsContact C-N 3.34Å; G39-G41 PolarHBondContact O-N 3.05Å; G41-L45 WeakPolarHBondContact O-CB 3.09Å; G41-L45 PolarHBondContact O-N 3.15Å
42	A	70.3	Confident	68	Low	43 Å²	43	56.6 Å²	56.6	36%	0.355	31%	0.311	S	S	.	.	H	α-helix	trans	-69	-43.3	174.6	0	0	0	0	0	111.2	I38 G39 N40 A44 L45 T46 L76	I38-A42 WeakPolarHBondContact O-CB 3.48Å; I38-A42 PolarHBondContact O-N 3Å; G39-A42 WeakPolarHBondContact O-CB 3.23Å; G39-A42 PolarHBondContact O-N 3.04Å; N40-A42 VanDerWaalsContact C-N 3.32Å; N40-A42 PolarHBondContact O-N 3.08Å; A42-A44 VanDerWaalsContact C-N 3.35Å; A42-L45 PolarHBondContact O-N 3.35Å; A42-T46 PolarHBondContact O-N 2.8Å; A42-T46 PolarHBondContact O-OG1 3.18Å; A42-T46 VanDerWaalsContact O-OG1 3.04Å; A42-L76 HydrophobicContact CB-CD2 4.44Å
43	V	70.9	Confident	67.3	Low	99 Å²	99	56 Å²	56	60%	0.6	32%	0.32	S	S	*	.	H	α-helix	trans	-60.8	-44.9	173.9	173.7	0	0	0	0	110.8	G39 N40 L45 T46 N47	G39-V43 WeakPolarHBondContact O-CG2 3.17Å; G39-V43 PolarHBondContact O-N 3.14Å; N40-V43 PolarHBondContact O-N 2.8Å; V43-L45 PolarHBondContact O-N 3.17Å; V43-T46 PolarHBondContact O-N 3.27Å; V43-N47 WeakPolarHBondContact O-CB 3.25Å; V43-N47 PolarHBondContact O-N 2.85Å
44	A	69	Low	66.6	Low	15 Å²	15	56.5 Å²	56.5	12%	0.124	33%	0.33	C	S	.	.	H	α-helix	trans	-61	-44	176.9	0	0	0	0	0	112.3	N40 A42 N47 A48 T72 Y75	N40-A44 WeakPolarHBondContact O-CB 3.25Å; N40-A44 PolarHBondContact O-N 3.3Å; A42-A44 VanDerWaalsContact C-N 3.35Å; A44-N47 PolarHBondContact O-N 3.23Å; A44-A48 WeakPolarHBondContact O-CB 3.42Å; A44-A48 PolarHBondContact O-N 3.24Å; A44-T72 WeakPolarHBondContact CB-OG1 2.89Å; A44-Y75 HydrophobicContact CB-CD2 4.41Å
45	L	69.1	Low	65.8	Low	35 Å²	35	61.4 Å²	61.4	18%	0.183	35%	0.352	C	S	.	.	H	α-helix	trans	-62.1	-45.2	174.3	177.8	63.7	0	0	0	111.6	G41 A42 V43 N47 A48 C49 W70 L76 I559	G41-L45 WeakPolarHBondContact O-CB 3.09Å; G41-L45 PolarHBondContact O-N 3.15Å; A42-L45 PolarHBondContact O-N 3.35Å; V43-L45 PolarHBondContact O-N 3.17Å; L45-N47 VanDerWaalsContact C-N 3.34Å; L45-N47 PolarHBondContact O-N 2.95Å; L45-A48 PolarHBondContact O-N 2.8Å; L45-C49 WeakPolarHBondContact O-CB 3.43Å; L45-C49 PolarHBondContact O-N 3.02Å; L45-C49 PolarHBondContact O-SG 3.32Å; L45-W70 HydrophobicContact CD1-CE3 4.46Å; L45-W70 HydrophobicContact CD1-CZ3 3.83Å; L45-L76 HydrophobicContact CD2-CD1 4.29Å; L45-I559 HydrophobicContact CD1-CD1 4.29Å
46	T	67.8	Low	64.3	Low	87 Å²	87	54.7 Å²	54.7	53%	0.534	33%	0.329	S	S	.	.	H	α-helix	trans	-61.3	-43.7	175.5	-59.5	0	0	0	0	111	A42 V43 A48 C49 V50	A42-T46 PolarHBondContact O-N 2.8Å; A42-T46 PolarHBondContact O-OG1 3.18Å; A42-T46 VanDerWaalsContact O-OG1 3.04Å; V43-T46 PolarHBondContact O-N 3.27Å; T46-A48 PolarHBondContact O-N 3.32Å; T46-C49 WeakPolarHBondContact O-CB 3.33Å; T46-C49 PolarHBondContact O-N 3.12Å; T46-V50 HydrophobicContact CG2-CG2 4.3Å; T46-V50 VanDerWaalsContact O-CG2 3.29Å; T46-V50 WeakPolarHBondContact O-CG2 3.49Å; T46-V50 PolarHBondContact O-N 2.74Å
47	N	65	Low	63.1	Low	89 Å²	89	50.4 Å²	50.4	48%	0.476	31%	0.307	S	S	.	.	H	α-helix	trans	-60.9	-44.4	176.8	-171.1	49.2	0	0	0	111.4	V43 A44 L45 C49 V50 A51	V43-N47 WeakPolarHBondContact O-CB 3.25Å; V43-N47 PolarHBondContact O-N 2.85Å; A44-N47 PolarHBondContact O-N 3.23Å; L45-N47 VanDerWaalsContact C-N 3.34Å; L45-N47 PolarHBondContact O-N 2.95Å; N47-C49 PolarHBondContact O-N 2.99Å; N47-V50 PolarHBondContact O-N 3.41Å; N47-A51 VanDerWaalsContact O-CB 3.31Å; N47-A51 WeakPolarHBondContact O-CB 3.24Å; N47-A51 PolarHBondContact O-N 2.96Å
48	A	63.6	Low	61.8	Low	2 Å²	2	52.1 Å²	52.1	2%	0.017	31%	0.313	C	S	.	.	H	α-helix	trans	-62.1	-41.9	175.9	0	0	0	0	0	112.1	A44 L45 T46 T52 W70	A44-A48 WeakPolarHBondContact O-CB 3.42Å; A44-A48 PolarHBondContact O-N 3.24Å; L45-A48 PolarHBondContact O-N 2.8Å; T46-A48 PolarHBondContact O-N 3.32Å; A48-T52 VanDerWaalsContact O-CB 3.26Å; A48-T52 WeakPolarHBondContact O-CB 3.32Å; A48-T52 PolarHBondContact O-N 2.76Å; A48-T52 PolarHBondContact O-OG1 3.48Å; A48-W70 HydrophobicContact CB-CD2 3.65Å; A48-W70 HydrophobicContact CB-CE3 3.76Å; A48-W70 HydrophobicContact CB-CG 4.23Å; A48-W70 HydrophobicContact CB-CH2 4.14Å; A48-W70 HydrophobicContact CB-CZ2 4.04Å; A48-W70 HydrophobicContact CB-CZ3 4Å
49	C	63.5	Low	59.9	Low	58 Å²	58	52 Å²	52	39%	0.392	32%	0.315	S	S	.	.	H	α-helix	trans	-63.4	-41.3	173.8	-71.3	0	0	0	0	112.6	L45 T46 N47 T52 A53	L45-C49 WeakPolarHBondContact O-CB 3.43Å; L45-C49 PolarHBondContact O-N 3.02Å; L45-C49 PolarHBondContact O-SG 3.32Å; T46-C49 WeakPolarHBondContact O-CB 3.33Å; T46-C49 PolarHBondContact O-N 3.12Å; N47-C49 PolarHBondContact O-N 2.99Å; C49-T52 WeakPolarHBondContact O-CB 3.46Å; C49-A53 WeakPolarHBondContact O-CB 3.41Å; C49-A53 PolarHBondContact O-N 3.35Å
50	V	61.5	Low	58.6	Low	67 Å²	67	60 Å²	60	41%	0.406	34%	0.343	S	S	.	.	H	α-helix	trans	-68.7	-46.5	178.1	170.6	0	0	0	0	110.7	T46 N47 T52 A53 L54	T46-V50 HydrophobicContact CG2-CG2 4.3Å; T46-V50 VanDerWaalsContact O-CG2 3.29Å; T46-V50 WeakPolarHBondContact O-CG2 3.49Å; T46-V50 PolarHBondContact O-N 2.74Å; N47-V50 PolarHBondContact O-N 3.41Å; V50-T52 PolarHBondContact O-N 3.09Å; V50-A53 PolarHBondContact O-N 3.32Å; V50-A53 VanDerWaalsContact O-N 3.09Å; V50-L54 HydrophobicContact CG1-CD1 3.65Å; V50-L54 HydrophobicContact CG1-CG 4.18Å; V50-L54 WeakPolarHBondContact O-CB 3.31Å; V50-L54 WeakPolarHBondContact O-CG 3.44Å; V50-L54 PolarHBondContact O-N 3.49Å
51	A	57.7	Low	57.1	Low	3 Å²	3	60.4 Å²	60.4	3%	0.025	35%	0.345	C	S	.	.	H	α-helix	trans	-57.5	-40.1	176.2	0	0	0	0	0	111.7	N47 A56 V66 T68	N47-A51 VanDerWaalsContact O-CB 3.31Å; N47-A51 WeakPolarHBondContact O-CB 3.24Å; N47-A51 PolarHBondContact O-N 2.96Å; A51-A56 PolarHBondContact O-N 3.49Å; A51-A56 VanDerWaalsContact O-N 3.08Å; A51-V66 HydrophobicContact CB-CB 4.33Å; A51-V66 HydrophobicContact CB-CG1 3.7Å; A51-T68 HydrophobicContact CB-CG2 3.87Å
52	T	55.6	Low	55.9	Low	20 Å²	20	65.9 Å²	65.9	12%	0.123	37%	0.373	C	S	.	.	H	α-helix	trans	-62.4	-48.6	172.7	-65	0	0	0	0	112.5	A48 C49 V50 L54 E55 W70 L544 L547	A48-T52 VanDerWaalsContact O-CB 3.26Å; A48-T52 WeakPolarHBondContact O-CB 3.32Å; A48-T52 PolarHBondContact O-N 2.76Å; A48-T52 PolarHBondContact O-OG1 3.48Å; C49-T52 WeakPolarHBondContact O-CB 3.46Å; V50-T52 PolarHBondContact O-N 3.09Å; T52-L54 VanDerWaalsContact C-N 3.29Å; T52-L54 PolarHBondContact O-N 3.36Å; T52-E55 PolarHBondContact O-N 3.26Å; T52-W70 VanDerWaalsContact OG1-CZ2 3.25Å; T52-W70 WeakPolarHBondContact OG1-CZ2 3.36Å; T52-L544 HydrophobicContact CG2-CB 3.44Å; T52-L544 VanDerWaalsContact CG2-CB 3.44Å; T52-L544 HydrophobicContact CG2-CD1 3.88Å; T52-L544 HydrophobicContact CG2-CD2 4.46Å; T52-L544 HydrophobicContact CG2-CG 4.09Å; T52-L544 WeakPolarHBondContact OG1-CD1 3.33Å; T52-L547 HydrophobicContact CG2-CD1 3.79Å
53	A	57	Low	54.4	Low	82 Å²	82	70.4 Å²	70.4	68%	0.678	39%	0.39	S	S	*	.	H	α-helix	trans	-67.7	-28.4	-178.8	0	0	0	0	0	113.2	C49 V50 E55	C49-A53 WeakPolarHBondContact O-CB 3.41Å; C49-A53 PolarHBondContact O-N 3.35Å; V50-A53 PolarHBondContact O-N 3.32Å; V50-A53 VanDerWaalsContact O-N 3.09Å; A53-E55 VanDerWaalsContact C-N 3.27Å; A53-E55 PolarHBondContact O-N 2.83Å
54	L	55.4	Low	52.9	Low	128 Å²	128	70.1 Å²	70.1	67%	0.67	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.5	6.2	178.7	-68.6	176.3	0	0	0	113.6	V50 T52 A56	V50-L54 HydrophobicContact CG1-CD1 3.65Å; V50-L54 HydrophobicContact CG1-CG 4.18Å; V50-L54 WeakPolarHBondContact O-CB 3.31Å; V50-L54 WeakPolarHBondContact O-CG 3.44Å; V50-L54 PolarHBondContact O-N 3.49Å; T52-L54 VanDerWaalsContact C-N 3.29Å; T52-L54 PolarHBondContact O-N 3.36Å; L54-A56 HydrophobicContact CB-CB 4.49Å; L54-A56 PolarHBondContact O-N 2.93Å
55	E	51.6	Low	51.7	Low	102 Å²	102	72.8 Å²	72.8	48%	0.477	39%	0.389	S	S	.	.	T	Hydrogen-bonded Turn	trans	53.8	23.1	-173.8	-58	-179.6	-176.3	0	0	113.2	T52 A53 V57 A545	T52-E55 PolarHBondContact O-N 3.26Å; A53-E55 VanDerWaalsContact C-N 3.27Å; A53-E55 PolarHBondContact O-N 2.83Å; E55-V57 PolarHBondContact O-N 3.34Å; E55-A545 HydrophobicContact CB-CB 3.98Å; E55-A545 HydrophobicContact CG-CB 4.13Å
56	A	45.7	Very low	50.4	Low	11 Å²	11	74.1 Å²	74.1	9%	0.091	40%	0.399	C	S	.	.			trans	-74.2	21.4	178.3	0	0	0	0	0	112.4	A51 L54 V66	A51-A56 PolarHBondContact O-N 3.49Å; A51-A56 VanDerWaalsContact O-N 3.08Å; L54-A56 HydrophobicContact CB-CB 4.49Å; L54-A56 PolarHBondContact O-N 2.93Å; A56-V66 HydrophobicContact CB-CB 3.58Å; A56-V66 HydrophobicContact CB-CG2 3.5Å; A56-V66 VanDerWaalsContact CB-CG2 3.5Å; A56-V66 PolarHBondContact O-N 2.81Å
57	V	46.7	Very low	49.6	Very low	5 Å²	5	70.7 Å²	70.7	3%	0.03	38%	0.377	C	S	.	.	S	Bend	trans	-106.7	107	-174.6	-169.3	0	0	0	0	107.3	E55 T59 T68 N543 L544	E55-V57 PolarHBondContact O-N 3.34Å; V57-T59 PolarHBondContact O-N 3.01Å; V57-T68 HydrophobicContact CG2-CG2 3.8Å; V57-N543 PolarHBondContact O-OD1 2.99Å; V57-L544 HydrophobicContact CG2-CB 4.28Å
58	K	45.6	Very low	49	Very low	78 Å²	78	67.6 Å²	67.6	34%	0.339	36%	0.362	S	S	.	.	S	Bend	trans	51.4	47.5	171.7	-64.9	-175.6	176.3	178.8	0	115.2
59	T	33.6	Very low	48.9	Very low	41 Å²	41	68.5 Å²	68.5	25%	0.252	37%	0.366	S	S	.	.			trans	-74.7	147.8	159.7	61	0	0	0	0	109.2	V57 L61 Q64	V57-T59 PolarHBondContact O-N 3.01Å; T59-L61 PolarHBondContact O-N 2.92Å; T59-Q64 VanDerWaalsContact CG2-OE1 3.24Å; T59-Q64 WeakPolarHBondContact OG1-CB 3.21Å; T59-Q64 PolarHBondContact OG1-OE1 3.38Å
60	H	42.5	Very low	48.9	Very low	202 Å²	202	66.2 Å²	66.2	94%	0.935	35%	0.349	S	S	*	.	S	Bend	trans	-62.9	-1.8	-179.6	-50.1	-66.3	0	0	0	113.8
61	L	40.3	Very low	49.1	Very low	102 Å²	102	64.3 Å²	64.3	53%	0.534	34%	0.336	S	S	.	.			trans	-103.1	109.5	-179.9	-75.2	152.7	0	0	0	108.4	T59 I63 Q64	T59-L61 PolarHBondContact O-N 2.92Å; L61-I63 PolarHBondContact O-N 2.9Å; L61-Q64 PolarHBondContact O-N 3.4Å
62	L	41.1	Very low	49.7	Very low	114 Å²	114	64.8 Å²	64.8	60%	0.597	34%	0.339	S	S	*	.	G	3₁₀ helix	trans	-48.2	-27	175.9	-147.3	79.3	0	0	0	113	Q64 Y65 V121	L62-Q64 VanDerWaalsContact C-N 3.26Å; L62-Q64 PolarHBondContact O-N 2.82Å; L62-Y65 WeakPolarHBondContact O-CB 3.24Å; L62-Y65 PolarHBondContact O-N 3.08Å; L62-V121 HydrophobicContact CD2-CG1 3.53Å; L62-V121 HydrophobicContact CD2-CG2 4.18Å; L62-V121 HydrophobicContact CG-CG1 4.11Å
63	I	38.1	Very low	50.4	Low	139 Å²	139	64.6 Å²	64.6	71%	0.713	34%	0.338	S	S	*	.	G	3₁₀ helix	trans	-67.3	-21	179.3	-63.8	165.3	0	0	0	113.2	L61	L61-I63 PolarHBondContact O-N 2.9Å
64	Q	40.3	Very low	51.2	Low	93 Å²	93	61 Å²	61	44%	0.435	31%	0.307	S	S	.	.	G	3₁₀ helix	trans	-106.4	8.7	-178.5	-78.3	175.8	-14.2	0	0	112.5	T59 L61 L62 V66	T59-Q64 VanDerWaalsContact CG2-OE1 3.24Å; T59-Q64 WeakPolarHBondContact OG1-CB 3.21Å; T59-Q64 PolarHBondContact OG1-OE1 3.38Å; L61-Q64 PolarHBondContact O-N 3.4Å; L62-Q64 VanDerWaalsContact C-N 3.26Å; L62-Q64 PolarHBondContact O-N 2.82Å; Q64-V66 VanDerWaalsContact C-N 3.33Å; Q64-V66 PolarHBondContact O-N 3.39Å
65	Y	43.7	Very low	52.2	Low	70 Å²	70	56.6 Å²	56.6	28%	0.275	28%	0.282	S	S	.	.			trans	-73.5	85.5	178.9	-151.8	-90.4	0	0	0	109.9	L62	L62-Y65 WeakPolarHBondContact O-CB 3.24Å; L62-Y65 PolarHBondContact O-N 3.08Å
66	V	43.1	Very low	53.5	Low	63 Å²	63	52.7 Å²	52.7	38%	0.382	27%	0.265	S	S	.	.			trans	-83	116.1	165.1	177	0	0	0	0	106.4	A51 A56 Q64 T68	A51-V66 HydrophobicContact CB-CB 4.33Å; A51-V66 HydrophobicContact CB-CG1 3.7Å; A56-V66 HydrophobicContact CB-CB 3.58Å; A56-V66 HydrophobicContact CB-CG2 3.5Å; A56-V66 VanDerWaalsContact CB-CG2 3.5Å; A56-V66 PolarHBondContact O-N 2.81Å; Q64-V66 VanDerWaalsContact C-N 3.33Å; Q64-V66 PolarHBondContact O-N 3.39Å; V66-T68 PolarHBondContact O-N 3.33Å
67	N	50.2	Low	54.9	Low	15 Å²	15	52.7 Å²	52.7	8%	0.08	26%	0.263	C	S	.	.			trans	-56.1	103.2	178.4	-121.8	-13.8	0	0	0	110.3	H69 F114 D115 N118	N67-H69 VanDerWaalsContact C-N 3.25Å; N67-H69 VanDerWaalsContact CG-CE1 3.42Å; N67-H69 PolarHBondContact ND2-CE1 3.42Å; N67-H69 PolarHBondContact ND2-NE2 3.33Å; N67-H69 PolarHBondContact O-N 2.78Å; N67-H69 PolarHBondContact OD1-CE1 3.39Å; N67-F114 VanDerWaalsContact ND2-CB 3.3Å; N67-F114 WeakPolarHBondContact ND2-CB 3.25Å; N67-F114 PolarHBondContact ND2-O 3.36Å; N67-D115 VanDerWaalsContact CB-OD1 3.28Å; N67-D115 WeakPolarHBondContact CB-OD1 3.43Å; N67-D115 PolarHBondContact ND2-N 2.9Å; N67-D115 PolarHBondContact ND2-OD1 3.5Å; N67-N118 WeakPolarHBondContact CB-ND2 3.46Å; N67-N118 PolarHBondContact ND2-ND2 3.16Å
68	T	52.1	Low	56.1	Low	25 Å²	25	52.4 Å²	52.4	15%	0.153	26%	0.261	C	S	.	.			trans	-81.2	73.2	174.1	47	0	0	0	0	109.5	A51 V57 V66 W70	A51-T68 HydrophobicContact CB-CG2 3.87Å; V57-T68 HydrophobicContact CG2-CG2 3.8Å; V66-T68 PolarHBondContact O-N 3.33Å; T68-W70 PolarHBondContact O-N 2.82Å
69	H	61	Low	57.3	Low	21 Å²	21	48.7 Å²	48.7	10%	0.097	25%	0.245	C	C	.	.			trans	-78.6	63.5	175.8	-66.6	-58.4	0	0	0	111.5	N67 I71 T72 F114 D115	N67-H69 VanDerWaalsContact C-N 3.25Å; N67-H69 VanDerWaalsContact CG-CE1 3.42Å; N67-H69 PolarHBondContact ND2-CE1 3.42Å; N67-H69 PolarHBondContact ND2-NE2 3.33Å; N67-H69 PolarHBondContact O-N 2.78Å; N67-H69 PolarHBondContact OD1-CE1 3.39Å; H69-I71 HydrophobicContact CB-CG2 4.27Å; H69-I71 PolarHBondContact O-N 3.21Å; H69-T72 HydrophobicContact CB-CG2 3.57Å; H69-T72 WeakPolarHBondContact O-CB 3.48Å; H69-T72 PolarHBondContact O-N 3.09Å; H69-T72 PolarHBondContact O-OG1 2.7Å; H69-F114 AromaticContact CE1-CD2 3.91Å; H69-D115 IonicContact CD2-OD1 3.55Å; H69-D115 PolarHBondContact CD2-OD1 2.94Å; H69-D115 IonicContact CD2-OD2 2.92Å; H69-D115 IonicContact NE2-OD1 3.49Å; H69-D115 PolarHBondContact NE2-OD1 2.97Å; H69-D115 VanDerWaalsContact NE2-OD1 3.12Å
70	W	64.9	Low	59.3	Low	9 Å²	9	48.1 Å²	48.1	3%	0.034	24%	0.244	C	C	.	.	G	3₁₀ helix	trans	-51.3	-30.5	175.2	-78.6	99.8	0	0	0	112.5	L45 A48 T52 T68 T72 C73 I539 L544 I559	L45-W70 HydrophobicContact CD1-CE3 4.46Å; L45-W70 HydrophobicContact CD1-CZ3 3.83Å; A48-W70 HydrophobicContact CB-CD2 3.65Å; A48-W70 HydrophobicContact CB-CE3 3.76Å; A48-W70 HydrophobicContact CB-CG 4.23Å; A48-W70 HydrophobicContact CB-CH2 4.14Å; A48-W70 HydrophobicContact CB-CZ2 4.04Å; A48-W70 HydrophobicContact CB-CZ3 4Å; T52-W70 VanDerWaalsContact OG1-CZ2 3.25Å; T52-W70 WeakPolarHBondContact OG1-CZ2 3.36Å; T68-W70 PolarHBondContact O-N 2.82Å; W70-T72 PolarHBondContact O-N 3.05Å; W70-C73 WeakPolarHBondContact O-CB 3.37Å; W70-C73 PolarHBondContact O-N 3.18Å; W70-C73 PolarHBondContact O-SG 2.99Å; W70-I539 HydrophobicContact CB-CG2 3.72Å; W70-I539 HydrophobicContact CD2-CG2 3.31Å; W70-I539 HydrophobicContact CE3-CG2 3.69Å; W70-I539 HydrophobicContact CG-CG2 3.35Å; W70-I539 HydrophobicContact CZ2-CG2 4.44Å; W70-I539 HydrophobicContact CZ3-CG2 4.4Å; W70-L544 HydrophobicContact CZ2-CD1 3.65Å; W70-I559 HydrophobicContact CH2-CD1 4.21Å; W70-I559 HydrophobicContact CZ3-CD1 3.76Å; W70-I559 HydrophobicContact CZ3-CG1 4.49Å
71	I	65.5	Low	60.6	Low	28 Å²	28	38.5 Å²	38.5	14%	0.144	20%	0.2	C	C	.	.	G	3₁₀ helix	trans	-55.9	-28.5	173.6	-165.5	164.5	0	0	0	113.9	H69 C73 V74 V107 V173	H69-I71 HydrophobicContact CB-CG2 4.27Å; H69-I71 PolarHBondContact O-N 3.21Å; I71-C73 PolarHBondContact O-N 3.26Å; I71-C73 VanDerWaalsContact O-N 3.14Å; I71-V74 WeakPolarHBondContact O-CB 3.42Å; I71-V74 VanDerWaalsContact O-CG1 3.3Å; I71-V74 WeakPolarHBondContact O-CG1 3.47Å; I71-V74 PolarHBondContact O-N 2.77Å; I71-V107 HydrophobicContact CB-CG1 4.32Å; I71-V107 HydrophobicContact CD1-CG2 3.91Å; I71-V107 HydrophobicContact CG1-CG1 3.96Å; I71-V107 HydrophobicContact CG1-CG2 3.74Å; I71-V107 HydrophobicContact CG2-CG1 3.88Å; I71-V173 HydrophobicContact CD1-CG1 4.46Å
72	T	69	Low	61.9	Low	13 Å²	13	34.1 Å²	34.1	8%	0.08	18%	0.177	C	C	.	.	G	3₁₀ helix	trans	-65.2	-13.7	175.5	59.5	0	0	0	0	113.4	A44 H69 W70 V74 Y75 V107 A111	A44-T72 WeakPolarHBondContact CB-OG1 2.89Å; H69-T72 HydrophobicContact CB-CG2 3.57Å; H69-T72 WeakPolarHBondContact O-CB 3.48Å; H69-T72 PolarHBondContact O-N 3.09Å; H69-T72 PolarHBondContact O-OG1 2.7Å; W70-T72 PolarHBondContact O-N 3.05Å; T72-V74 PolarHBondContact O-N 3.34Å; T72-Y75 HydrophobicContact CG2-CE2 4.22Å; T72-Y75 WeakPolarHBondContact O-CB 3.37Å; T72-Y75 WeakPolarHBondContact O-CD1 3.11Å; T72-Y75 VanDerWaalsContact O-CD2 3.3Å; T72-Y75 WeakPolarHBondContact O-CD2 3.32Å; T72-Y75 PolarHBondContact O-N 2.76Å; T72-V107 HydrophobicContact CG2-CG1 4.06Å; T72-A111 HydrophobicContact CG2-CB 3.82Å
73	C	71.6	Confident	63.3	Low	16 Å²	16	31 Å²	31	11%	0.108	16%	0.16	C	C	.	.	G	3₁₀ helix	trans	-58.4	-16.7	168.7	-64.6	0	0	0	0	112.7	W70 I71 Y75 L76	W70-C73 WeakPolarHBondContact O-CB 3.37Å; W70-C73 PolarHBondContact O-N 3.18Å; W70-C73 PolarHBondContact O-SG 2.99Å; I71-C73 PolarHBondContact O-N 3.26Å; I71-C73 VanDerWaalsContact O-N 3.14Å; C73-Y75 PolarHBondContact O-N 3.35Å; C73-Y75 VanDerWaalsContact O-N 3.1Å; C73-L76 WeakPolarHBondContact O-CB 3.15Å; C73-L76 PolarHBondContact O-N 3.48Å; C73-L76 VanDerWaalsContact O-N 3.08Å
74	V	73.6	Confident	64.8	Low	5 Å²	5	26.3 Å²	26.3	3%	0.03	14%	0.136	C	C	.	.	H	α-helix	trans	-54.7	-24.5	170.8	75.7	0	0	0	0	113	I71 T72 L76 L77 T78 M100 I103 V107	I71-V74 WeakPolarHBondContact O-CB 3.42Å; I71-V74 VanDerWaalsContact O-CG1 3.3Å; I71-V74 WeakPolarHBondContact O-CG1 3.47Å; I71-V74 PolarHBondContact O-N 2.77Å; T72-V74 PolarHBondContact O-N 3.34Å; V74-L76 PolarHBondContact O-N 3.12Å; V74-L77 WeakPolarHBondContact O-CB 3.35Å; V74-L77 PolarHBondContact O-N 2.54Å; V74-T78 PolarHBondContact O-N 3.01Å; V74-T78 PolarHBondContact O-OG1 2.86Å; V74-M100 HydrophobicContact CG2-CE 3.62Å; V74-I103 HydrophobicContact CG2-CG2 4.04Å; V74-V107 HydrophobicContact CG1-CB 3.92Å; V74-V107 HydrophobicContact CG1-CG1 3.84Å; V74-V107 HydrophobicContact CG1-CG2 4.03Å
75	Y	76.4	Confident	65.9	Low	37 Å²	37	22.5 Å²	22.5	15%	0.145	12%	0.12	C	C	.	.	H	α-helix	trans	-57.5	-35.7	176.2	-60.2	-10.7	0	0	0	112.3	M37 N40 A44 T72 C73 T78 G79 T104 V107 A108	M37-Y75 HydrophobicContact CE-CD1 4.18Å; M37-Y75 HydrophobicContact CE-CG 4.21Å; N40-Y75 HydrophobicContact CB-CD2 4.31Å; A44-Y75 HydrophobicContact CB-CD2 4.41Å; T72-Y75 HydrophobicContact CG2-CE2 4.22Å; T72-Y75 WeakPolarHBondContact O-CB 3.37Å; T72-Y75 WeakPolarHBondContact O-CD1 3.11Å; T72-Y75 VanDerWaalsContact O-CD2 3.3Å; T72-Y75 WeakPolarHBondContact O-CD2 3.32Å; T72-Y75 PolarHBondContact O-N 2.76Å; C73-Y75 PolarHBondContact O-N 3.35Å; C73-Y75 VanDerWaalsContact O-N 3.1Å; Y75-T78 PolarHBondContact O-N 3.03Å; Y75-G79 PolarHBondContact O-N 3.36Å; Y75-T104 HydrophobicContact CD1-CG2 3.34Å; Y75-T104 HydrophobicContact CE1-CG2 3.67Å; Y75-T104 HydrophobicContact CG-CG2 4.42Å; Y75-V107 HydrophobicContact CE1-CG1 4.44Å; Y75-A108 HydrophobicContact CE1-CB 4.03Å; Y75-A108 VanDerWaalsContact OH-CA 3.24Å; Y75-A108 WeakPolarHBondContact OH-CA 3.17Å; Y75-A108 VanDerWaalsContact OH-CB 3.27Å; Y75-A108 WeakPolarHBondContact OH-CB 3.36Å
76	L	77.7	Confident	66.9	Low	20 Å²	20	21.4 Å²	21.4	11%	0.105	12%	0.117	C	C	.	.	H	α-helix	trans	-61.9	-45.6	175.1	-67.4	175.7	0	0	0	111.4	I38 A42 L45 C73 V74 T78 G79 A80 F563	I38-L76 HydrophobicContact CG2-CD2 4.17Å; I38-L76 WeakPolarHBondContact O-CD2 3.3Å; A42-L76 HydrophobicContact CB-CD2 4.44Å; L45-L76 HydrophobicContact CD2-CD1 4.29Å; C73-L76 WeakPolarHBondContact O-CB 3.15Å; C73-L76 PolarHBondContact O-N 3.48Å; C73-L76 VanDerWaalsContact O-N 3.08Å; V74-L76 PolarHBondContact O-N 3.12Å; L76-T78 VanDerWaalsContact C-N 3.31Å; L76-T78 PolarHBondContact O-N 2.98Å; L76-G79 PolarHBondContact O-N 3.5Å; L76-A80 WeakPolarHBondContact O-CB 3.19Å; L76-A80 PolarHBondContact O-N 2.86Å; L76-F563 HydrophobicContact CB-CE1 4.28Å; L76-F563 HydrophobicContact CD1-CE1 3.88Å; L76-F563 HydrophobicContact CD1-CZ 3.62Å
77	L	76.6	Confident	68.1	Low	10 Å²	10	26.8 Å²	26.8	5%	0.052	14%	0.135	C	C	.	.	H	α-helix	trans	-66.5	-37.3	-179.8	-55.7	-176.1	0	0	0	111	V74 S81 M100 V532 F566	V74-L77 WeakPolarHBondContact O-CB 3.35Å; V74-L77 PolarHBondContact O-N 2.54Å; L77-S81 WeakPolarHBondContact O-CB 3.31Å; L77-S81 PolarHBondContact O-N 2.85Å; L77-S81 PolarHBondContact O-OG 3.48Å; L77-M100 HydrophobicContact CB-CE 3.41Å; L77-M100 VanDerWaalsContact CB-CE 3.41Å; L77-M100 HydrophobicContact CD1-CE 3.95Å; L77-M100 HydrophobicContact CG-CE 4.33Å; L77-V532 HydrophobicContact CD1-CG1 4.35Å; L77-F566 HydrophobicContact CB-CD2 4.03Å; L77-F566 HydrophobicContact CB-CE2 3.99Å; L77-F566 HydrophobicContact CD1-CD2 4.42Å; L77-F566 HydrophobicContact CD2-CB 3.74Å; L77-F566 HydrophobicContact CD2-CD1 4.22Å; L77-F566 HydrophobicContact CD2-CD2 3.79Å; L77-F566 HydrophobicContact CD2-CE2 4.46Å; L77-F566 HydrophobicContact CD2-CG 3.65Å; L77-F566 HydrophobicContact CG-CD2 4.3Å; L77-F566 VanDerWaalsContact O-CZ 3.31Å; L77-F566 WeakPolarHBondContact O-CZ 3.28Å
78	T	72	Confident	68.7	Low	0 Å²	0	29 Å²	29	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-69.4	-45.2	177.7	-65.6	0	0	0	0	112.5	M37 V74 Y75 L76 A80 S81 T82 M100 N101 T104	M37-T78 HydrophobicContact CE-CG2 4.03Å; V74-T78 PolarHBondContact O-N 3.01Å; V74-T78 PolarHBondContact O-OG1 2.86Å; Y75-T78 PolarHBondContact O-N 3.03Å; L76-T78 VanDerWaalsContact C-N 3.31Å; L76-T78 PolarHBondContact O-N 2.98Å; T78-A80 VanDerWaalsContact C-N 3.34Å; T78-A80 PolarHBondContact O-N 3.43Å; T78-S81 WeakPolarHBondContact CA-OG 3.46Å; T78-S81 PolarHBondContact O-N 3.26Å; T78-S81 PolarHBondContact O-OG 3.14Å; T78-T82 WeakPolarHBondContact O-CB 3.42Å; T78-T82 PolarHBondContact O-N 3.11Å; T78-T82 PolarHBondContact O-OG1 2.89Å; T78-M100 PolarHBondContact OG1-O 2.94Å; T78-M100 VanDerWaalsContact OG1-O 3.04Å; T78-N101 HydrophobicContact CG2-CB 4.3Å; T78-N101 WeakPolarHBondContact CG2-OD1 3.43Å; T78-T104 WeakPolarHBondContact CB-OG1 3.39Å; T78-T104 HydrophobicContact CG2-CG2 4.18Å; T78-T104 PolarHBondContact OG1-OG1 3.26Å
79	G	70.5	Confident	69.1	Low	0 Å²	0	34.7 Å²	34.7	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-59.5	-45.4	173.1	0	0	0	0	0	111.8	G34 Y75 L76 S81 T82 M83	G34-G79 WeakPolarHBondContact O-CA 3.43Å; Y75-G79 PolarHBondContact O-N 3.36Å; L76-G79 PolarHBondContact O-N 3.5Å; G79-S81 PolarHBondContact O-N 2.76Å; G79-T82 PolarHBondContact O-N 3.46Å; G79-M83 WeakPolarHBondContact O-CG 3.39Å; G79-M83 PolarHBondContact O-N 3.45Å
80	A	75	Confident	68.9	Low	28 Å²	28	35.2 Å²	35.2	23%	0.231	17%	0.169	C	C	.	.	H	α-helix	trans	-61.6	-45.5	175.8	0	0	0	0	0	112.5	L76 T78 T82 M83 L84 F566	L76-A80 WeakPolarHBondContact O-CB 3.19Å; L76-A80 PolarHBondContact O-N 2.86Å; T78-A80 VanDerWaalsContact C-N 3.34Å; T78-A80 PolarHBondContact O-N 3.43Å; A80-T82 VanDerWaalsContact C-N 3.29Å; A80-T82 PolarHBondContact O-N 2.78Å; A80-M83 PolarHBondContact O-N 3.37Å; A80-L84 VanDerWaalsContact O-CG 3.27Å; A80-L84 WeakPolarHBondContact O-CG 3.47Å; A80-L84 PolarHBondContact O-N 3.14Å; A80-F566 HydrophobicContact CB-CE1 3.62Å; A80-F566 HydrophobicContact CB-CZ 4.04Å
81	S	69.4	Low	68.6	Low	1 Å²	1	38.1 Å²	38.1	1%	0.007	19%	0.185	C	C	.	.	H	α-helix	trans	-60.4	-39.7	177.5	71.7	0	0	0	0	112	L77 T78 G79 L84 V85 A97	L77-S81 WeakPolarHBondContact O-CB 3.31Å; L77-S81 PolarHBondContact O-N 2.85Å; L77-S81 PolarHBondContact O-OG 3.48Å; T78-S81 WeakPolarHBondContact CA-OG 3.46Å; T78-S81 PolarHBondContact O-N 3.26Å; T78-S81 PolarHBondContact O-OG 3.14Å; G79-S81 PolarHBondContact O-N 2.76Å; S81-L84 PolarHBondContact O-N 2.89Å; S81-V85 WeakPolarHBondContact O-CG2 3.42Å; S81-V85 PolarHBondContact O-N 2.81Å; S81-V85 VanDerWaalsContact O-N 3.14Å; S81-A97 WeakPolarHBondContact OG-CA 3.46Å
82	T	67.9	Low	68.3	Low	9 Å²	9	38.6 Å²	38.6	6%	0.055	19%	0.186	C	C	.	.	H	α-helix	trans	-65.6	-41.5	178.4	-58.9	0	0	0	0	111.7	L30 T78 G79 A80 L84 V85	L30-T82 HydrophobicContact CD1-CG2 3.5Å; L30-T82 VanDerWaalsContact CD1-CG2 3.5Å; L30-T82 HydrophobicContact CG-CG2 3.84Å; T78-T82 WeakPolarHBondContact O-CB 3.42Å; T78-T82 PolarHBondContact O-N 3.11Å; T78-T82 PolarHBondContact O-OG1 2.89Å; G79-T82 PolarHBondContact O-N 3.46Å; A80-T82 VanDerWaalsContact C-N 3.29Å; A80-T82 PolarHBondContact O-N 2.78Å; T82-L84 VanDerWaalsContact C-N 3.33Å; T82-L84 PolarHBondContact O-N 3.09Å; T82-V85 WeakPolarHBondContact O-CB 3.45Å; T82-V85 PolarHBondContact O-N 2.89Å
83	M	70.4	Confident	67.9	Low	48 Å²	48	38 Å²	38	24%	0.236	18%	0.183	C	C	.	.	H	α-helix	trans	-66.8	-34.5	174.4	-66.6	-174.3	76.7	0	0	112.6	W35 I38 G79 A80 E86 K87	W35-M83 HydrophobicContact CD2-CE 4.22Å; W35-M83 HydrophobicContact CD2-SD 4.3Å; W35-M83 HydrophobicContact CZ2-CE 3.78Å; I38-M83 HydrophobicContact CD1-SD 3.53Å; I38-M83 VanDerWaalsContact CD1-SD 3.53Å; G79-M83 WeakPolarHBondContact O-CG 3.39Å; G79-M83 PolarHBondContact O-N 3.45Å; A80-M83 PolarHBondContact O-N 3.37Å; M83-E86 PolarHBondContact O-N 3.43Å; M83-K87 PolarHBondContact O-N 3.45Å
84	L	69	Low	67.4	Low	41 Å²	41	39.6 Å²	39.6	22%	0.215	19%	0.188	C	C	.	.	H	α-helix	trans	-68.8	-34.1	179.5	-72.5	168.3	0	0	0	112.6	A80 S81 T82 E86 K87 L88 F93 F566 C570	A80-L84 VanDerWaalsContact O-CG 3.27Å; A80-L84 WeakPolarHBondContact O-CG 3.47Å; A80-L84 PolarHBondContact O-N 3.14Å; S81-L84 PolarHBondContact O-N 2.89Å; T82-L84 VanDerWaalsContact C-N 3.33Å; T82-L84 PolarHBondContact O-N 3.09Å; L84-E86 VanDerWaalsContact C-N 3.27Å; L84-E86 PolarHBondContact O-N 3.24Å; L84-K87 PolarHBondContact O-N 2.93Å; L84-L88 HydrophobicContact CD2-CD1 3.82Å; L84-L88 WeakPolarHBondContact O-CB 3.31Å; L84-L88 PolarHBondContact O-N 3.26Å; L84-F93 HydrophobicContact CB-CD1 3.7Å; L84-F93 HydrophobicContact CB-CE1 3.98Å; L84-F93 HydrophobicContact CB-CG 4.25Å; L84-F93 HydrophobicContact CD1-CD1 4.3Å; L84-F93 HydrophobicContact CD1-CE1 3.95Å; L84-F93 HydrophobicContact CG-CE1 4.43Å; L84-F566 HydrophobicContact CD1-CE1 4.2Å; L84-F566 HydrophobicContact CD1-CZ 4.48Å; L84-C570 HydrophobicContact CD1-CB 4.1Å; L84-C570 WeakPolarHBondContact CD1-SG 3.29Å
85	V	64.5	Low	66.8	Low	14 Å²	14	41 Å²	41	9%	0.085	19%	0.193	C	C	.	.	H	α-helix	trans	-52.2	-49.4	172.9	171.1	0	0	0	0	110.8	L30 S81 T82 R89 F93 H94 A97	L30-V85 HydrophobicContact CD2-CG1 4.28Å; S81-V85 WeakPolarHBondContact O-CG2 3.42Å; S81-V85 PolarHBondContact O-N 2.81Å; S81-V85 VanDerWaalsContact O-N 3.14Å; T82-V85 WeakPolarHBondContact O-CB 3.45Å; T82-V85 PolarHBondContact O-N 2.89Å; V85-R89 VanDerWaalsContact O-CA 3.25Å; V85-R89 WeakPolarHBondContact O-CA 3.21Å; V85-R89 PolarHBondContact O-N 3.43Å; V85-F93 HydrophobicContact CG2-CB 4.06Å; V85-F93 WeakPolarHBondContact CG2-O 3.44Å; V85-H94 VanDerWaalsContact CG1-CD2 3.5Å; V85-H94 WeakPolarHBondContact CG1-CD2 3.27Å; V85-H94 WeakPolarHBondContact CG1-NE2 3.11Å; V85-A97 HydrophobicContact CG2-CB 3.41Å; V85-A97 VanDerWaalsContact CG2-CB 3.41Å
86	E	64.2	Low	66.2	Low	47 Å²	47	40.1 Å²	40.1	22%	0.22	19%	0.191	C	C	.	.	H	α-helix	trans	-71.5	-40.4	-174.8	-162.9	-131.3	173.7	0	0	112.2	K27 L30 I31 M83 L84 R89	K27-E86 WeakPolarHBondContact CB-OE1 3.46Å; L30-E86 HydrophobicContact CD2-CB 4.13Å; I31-E86 WeakPolarHBondContact CD1-OE1 3.12Å; I31-E86 WeakPolarHBondContact CD1-OE2 3.44Å; I31-E86 VanDerWaalsContact CG1-CD 3.43Å; I31-E86 WeakPolarHBondContact CG1-OE2 3.2Å; M83-E86 PolarHBondContact O-N 3.43Å; L84-E86 VanDerWaalsContact C-N 3.27Å; L84-E86 PolarHBondContact O-N 3.24Å; E86-R89 WeakPolarHBondContact O-CG 3.5Å
87	K	67.5	Low	65.5	Low	175 Å²	175	39.4 Å²	39.4	76%	0.761	19%	0.188	S	C	*	.	H	α-helix	trans	-74.5	-38.4	-176.4	-168.5	170.9	-176	173.6	0	113.1	M83 L84	M83-K87 PolarHBondContact O-N 3.45Å; L84-K87 PolarHBondContact O-N 2.93Å
88	L	63.7	Low	64.9	Low	63 Å²	63	42.2 Å²	42.2	33%	0.33	20%	0.202	S	C	.	.	H	α-helix	trans	-102.5	-23.9	-173	-64	171.8	0	0	0	112.7	L84 L90 F93 V574	L84-L88 HydrophobicContact CD2-CD1 3.82Å; L84-L88 WeakPolarHBondContact O-CB 3.31Å; L84-L88 PolarHBondContact O-N 3.26Å; L88-L90 HydrophobicContact CB-CG 4.34Å; L88-L90 WeakPolarHBondContact O-CG 3.28Å; L88-L90 PolarHBondContact O-N 3.33Å; L88-F93 HydrophobicContact CB-CD2 3.63Å; L88-F93 HydrophobicContact CB-CE2 3.61Å; L88-F93 HydrophobicContact CD1-CD2 3.91Å; L88-F93 HydrophobicContact CD1-CE1 4.07Å; L88-F93 HydrophobicContact CD1-CE2 3.14Å; L88-F93 HydrophobicContact CD1-CZ 3.23Å; L88-F93 HydrophobicContact CG-CD2 4.39Å; L88-F93 HydrophobicContact CG-CE2 3.96Å; L88-F93 HydrophobicContact CG-CZ 4.46Å; L88-V574 HydrophobicContact CD1-CG2 4.26Å
89	R	60.9	Low	64.6	Low	143 Å²	143	42.6 Å²	42.6	54%	0.54	21%	0.205	S	C	.	.			trans	48.7	31	178.6	-57.9	-168.7	-174.6	160.7	9.4	114.4	K27 V85 E86	K27-R89 VanDerWaalsContact NZ-NH2 3.2Å; V85-R89 VanDerWaalsContact O-CA 3.25Å; V85-R89 WeakPolarHBondContact O-CA 3.21Å; V85-R89 PolarHBondContact O-N 3.43Å; E86-R89 WeakPolarHBondContact O-CG 3.5Å
90	L	56.3	Low	64.5	Low	33 Å²	33	43.4 Å²	43.4	17%	0.173	21%	0.209	C	C	.	.			trans	-95.1	147.6	176.2	-49.6	176.8	0	0	0	110.7	L88 F92 F93 H94 V574 D577	L88-L90 HydrophobicContact CB-CG 4.34Å; L88-L90 WeakPolarHBondContact O-CG 3.28Å; L88-L90 PolarHBondContact O-N 3.33Å; L90-F92 VanDerWaalsContact C-N 3.26Å; L90-F92 PolarHBondContact O-N 3.49Å; L90-F93 HydrophobicContact CB-CD2 3.91Å; L90-F93 HydrophobicContact CB-CE2 4.45Å; L90-F93 HydrophobicContact CD1-CD2 4.24Å; L90-F93 HydrophobicContact CD1-CE2 3.94Å; L90-F93 HydrophobicContact CG-CD2 4.25Å; L90-F93 HydrophobicContact CG-CE2 4.41Å; L90-F93 PolarHBondContact O-N 2.98Å; L90-F93 VanDerWaalsContact O-N 3.13Å; L90-H94 PolarHBondContact O-N 2.83Å; L90-H94 PolarHBondContact O-ND1 3.18Å; L90-V574 HydrophobicContact CD1-CB 4.25Å; L90-V574 HydrophobicContact CD1-CG1 4.06Å; L90-V574 HydrophobicContact CD1-CG2 3.93Å; L90-D577 WeakPolarHBondContact CB-OD2 3.25Å; L90-D577 HydrophobicContact CD1-CB 4.33Å
91	N	58.9	Low	63.9	Low	70 Å²	70	45.1 Å²	45.1	37%	0.374	21%	0.214	S	C	.	.	H	α-helix	trans	-57.7	-38.5	-178.5	-71.1	-26.2	0	0	0	111.9	F93 H94 Y95	N91-F93 VanDerWaalsContact C-N 3.34Å; N91-F93 PolarHBondContact O-N 3.46Å; N91-H94 WeakPolarHBondContact O-CB 3.41Å; N91-H94 PolarHBondContact O-N 3.42Å; N91-Y95 HydrophobicContact CB-CE2 4.09Å; N91-Y95 VanDerWaalsContact O-CD2 3.27Å; N91-Y95 WeakPolarHBondContact O-CD2 3.33Å; N91-Y95 PolarHBondContact O-N 3.47Å; N91-Y95 VanDerWaalsContact O-N 3.15Å
92	F	59.3	Low	63.7	Low	38 Å²	38	46.5 Å²	46.5	17%	0.167	22%	0.222	C	C	.	.	H	α-helix	trans	-60.5	-43	177.3	-174.8	-77.7	0	0	0	112.6	L90 H94 Y95 L96 A573 D577	L90-F92 VanDerWaalsContact C-N 3.26Å; L90-F92 PolarHBondContact O-N 3.49Å; F92-H94 PolarHBondContact O-N 3.24Å; F92-Y95 CarbonylContact O-C 3.59Å; F92-Y95 WeakPolarHBondContact O-CA 3.26Å; F92-Y95 WeakPolarHBondContact O-CB 3.42Å; F92-Y95 PolarHBondContact O-N 3.16Å; F92-L96 HydrophobicContact CD1-CB 4.03Å; F92-L96 HydrophobicContact CE1-CB 3.74Å; F92-L96 HydrophobicContact CE1-CD1 4.37Å; F92-L96 HydrophobicContact CE1-CD2 4.11Å; F92-L96 HydrophobicContact CE1-CG 4.28Å; F92-L96 WeakPolarHBondContact O-CB 3.17Å; F92-L96 PolarHBondContact O-N 3.46Å; F92-A573 HydrophobicContact CB-CB 4.35Å; F92-A573 HydrophobicContact CD1-CB 3.06Å; F92-A573 HydrophobicContact CD2-CB 4Å; F92-A573 HydrophobicContact CE1-CB 3.08Å; F92-A573 HydrophobicContact CE2-CB 4.01Å; F92-A573 HydrophobicContact CG-CB 3.54Å; F92-A573 HydrophobicContact CZ-CB 3.57Å; F92-D577 WeakPolarHBondContact CB-OD1 3Å; F92-D577 WeakPolarHBondContact CB-OD2 3.02Å; F92-D577 PolarHBondContact N-OD2 3.49Å
93	F	60.9	Low	63.6	Low	1 Å²	1	47.2 Å²	47.2	0%	0.004	23%	0.225	C	C	.	.	H	α-helix	trans	-63.5	-32.7	-179	-73.9	-66.6	0	0	0	112	L84 V85 L88 L90 N91 L96 A97 C570 V574	L84-F93 HydrophobicContact CB-CD1 3.7Å; L84-F93 HydrophobicContact CB-CE1 3.98Å; L84-F93 HydrophobicContact CB-CG 4.25Å; L84-F93 HydrophobicContact CD1-CD1 4.3Å; L84-F93 HydrophobicContact CD1-CE1 3.95Å; L84-F93 HydrophobicContact CG-CE1 4.43Å; V85-F93 HydrophobicContact CG2-CB 4.06Å; V85-F93 WeakPolarHBondContact CG2-O 3.44Å; L88-F93 HydrophobicContact CB-CD2 3.63Å; L88-F93 HydrophobicContact CB-CE2 3.61Å; L88-F93 HydrophobicContact CD1-CD2 3.91Å; L88-F93 HydrophobicContact CD1-CE1 4.07Å; L88-F93 HydrophobicContact CD1-CE2 3.14Å; L88-F93 HydrophobicContact CD1-CZ 3.23Å; L88-F93 HydrophobicContact CG-CD2 4.39Å; L88-F93 HydrophobicContact CG-CE2 3.96Å; L88-F93 HydrophobicContact CG-CZ 4.46Å; L90-F93 HydrophobicContact CB-CD2 3.91Å; L90-F93 HydrophobicContact CB-CE2 4.45Å; L90-F93 HydrophobicContact CD1-CD2 4.24Å; L90-F93 HydrophobicContact CD1-CE2 3.94Å; L90-F93 HydrophobicContact CG-CD2 4.25Å; L90-F93 HydrophobicContact CG-CE2 4.41Å; L90-F93 PolarHBondContact O-N 2.98Å; L90-F93 VanDerWaalsContact O-N 3.13Å; N91-F93 VanDerWaalsContact C-N 3.34Å; N91-F93 PolarHBondContact O-N 3.46Å; F93-L96 HydrophobicContact CD1-CD2 4.41Å; F93-A97 WeakPolarHBondContact O-CB 3.02Å; F93-A97 PolarHBondContact O-N 2.76Å; F93-C570 HydrophobicContact CE1-CB 3.86Å; F93-C570 HydrophobicContact CZ-CB 4.34Å; F93-C570 WeakPolarHBondContact CZ-O 3.34Å; F93-V574 HydrophobicContact CE2-CG2 3.34Å; F93-V574 HydrophobicContact CZ-CG2 3.38Å
94	H	61.1	Low	63.5	Low	48 Å²	48	45.2 Å²	45.2	22%	0.222	22%	0.215	C	C	.	.	H	α-helix	trans	-62.8	-46.3	171.7	-65.2	81.7	0	0	0	110.3	V85 L90 N91 F92 A97 I98	V85-H94 VanDerWaalsContact CG1-CD2 3.5Å; V85-H94 WeakPolarHBondContact CG1-CD2 3.27Å; V85-H94 WeakPolarHBondContact CG1-NE2 3.11Å; L90-H94 PolarHBondContact O-N 2.83Å; L90-H94 PolarHBondContact O-ND1 3.18Å; N91-H94 WeakPolarHBondContact O-CB 3.41Å; N91-H94 PolarHBondContact O-N 3.42Å; F92-H94 PolarHBondContact O-N 3.24Å; H94-A97 PolarHBondContact O-N 2.82Å; H94-I98 WeakPolarHBondContact O-CB 3.38Å; H94-I98 WeakPolarHBondContact O-CD1 3.38Å; H94-I98 WeakPolarHBondContact O-CG1 3.45Å; H94-I98 PolarHBondContact O-N 2.94Å
95	Y	61.4	Low	63.5	Low	34 Å²	34	48.9 Å²	48.9	13%	0.133	23%	0.233	C	C	.	.	H	α-helix	trans	-63.4	-44.3	176.9	-55	-36.3	0	0	0	113	N91 F92 I98 C99 V195 F198	N91-Y95 HydrophobicContact CB-CE2 4.09Å; N91-Y95 VanDerWaalsContact O-CD2 3.27Å; N91-Y95 WeakPolarHBondContact O-CD2 3.33Å; N91-Y95 PolarHBondContact O-N 3.47Å; N91-Y95 VanDerWaalsContact O-N 3.15Å; F92-Y95 CarbonylContact O-C 3.59Å; F92-Y95 WeakPolarHBondContact O-CA 3.26Å; F92-Y95 WeakPolarHBondContact O-CB 3.42Å; F92-Y95 PolarHBondContact O-N 3.16Å; Y95-I98 PolarHBondContact O-N 2.79Å; Y95-C99 PolarHBondContact O-N 3.09Å; Y95-C99 PolarHBondContact O-SG 3.4Å; Y95-V195 HydrophobicContact CD1-CB 4.31Å; Y95-V195 HydrophobicContact CD1-CG1 3.72Å; Y95-V195 VanDerWaalsContact CE1-CA 3.46Å; Y95-V195 HydrophobicContact CE1-CB 3.57Å; Y95-V195 HydrophobicContact CE1-CG1 3.38Å; Y95-V195 HydrophobicContact CE1-CG2 3.58Å; Y95-F198 HydrophobicContact CD2-CB 3.99Å; Y95-F198 HydrophobicContact CE2-CB 4.18Å; Y95-F198 HydrophobicContact CE2-CD2 4.39Å; Y95-F198 HydrophobicContact CE2-CG 4.39Å; Y95-F198 HydrophobicContact CG-CB 4.31Å
96	L	63.6	Low	63.5	Low	19 Å²	19	49.8 Å²	49.8	10%	0.099	24%	0.236	C	C	.	.	H	α-helix	trans	-61.3	-48.3	176.8	-178.8	66.7	0	0	0	110.5	F92 F93 I98 C99 M100 F566	F92-L96 HydrophobicContact CD1-CB 4.03Å; F92-L96 HydrophobicContact CE1-CB 3.74Å; F92-L96 HydrophobicContact CE1-CD1 4.37Å; F92-L96 HydrophobicContact CE1-CD2 4.11Å; F92-L96 HydrophobicContact CE1-CG 4.28Å; F92-L96 WeakPolarHBondContact O-CB 3.17Å; F92-L96 PolarHBondContact O-N 3.46Å; F93-L96 HydrophobicContact CD1-CD2 4.41Å; L96-I98 VanDerWaalsContact C-N 3.33Å; L96-I98 PolarHBondContact O-N 2.82Å; L96-C99 PolarHBondContact O-N 3.42Å; L96-M100 HydrophobicContact CD1-CG 4.04Å; L96-M100 HydrophobicContact CG-CG 4.2Å; L96-M100 WeakPolarHBondContact O-CB 3.44Å; L96-M100 VanDerWaalsContact O-CG 3.24Å; L96-M100 WeakPolarHBondContact O-CG 3.03Å; L96-M100 PolarHBondContact O-N 3.2Å; L96-F566 HydrophobicContact CD2-CE2 4.34Å
97	A	62.9	Low	63.7	Low	5 Å²	5	47.7 Å²	47.7	4%	0.041	23%	0.226	C	C	.	.	H	α-helix	trans	-62.7	-40.4	178.7	0	0	0	0	0	111.6	S81 V85 F93 H94 M100 N101	S81-A97 WeakPolarHBondContact OG-CA 3.46Å; V85-A97 HydrophobicContact CG2-CB 3.41Å; V85-A97 VanDerWaalsContact CG2-CB 3.41Å; F93-A97 WeakPolarHBondContact O-CB 3.02Å; F93-A97 PolarHBondContact O-N 2.76Å; H94-A97 PolarHBondContact O-N 2.82Å; A97-M100 PolarHBondContact O-N 3.25Å; A97-N101 WeakPolarHBondContact O-CB 3.29Å; A97-N101 VanDerWaalsContact O-CG 3.22Å; A97-N101 PolarHBondContact O-N 3.17Å; A97-N101 PolarHBondContact O-ND2 2.95Å
98	I	64	Low	63.6	Low	69 Å²	69	41 Å²	41	35%	0.354	20%	0.203	S	C	.	.	H	α-helix	trans	-60.1	-50.1	173.5	-69.3	163.2	0	0	0	110.2	H94 Y95 L96 M100 N101 L102	H94-I98 WeakPolarHBondContact O-CB 3.38Å; H94-I98 WeakPolarHBondContact O-CD1 3.38Å; H94-I98 WeakPolarHBondContact O-CG1 3.45Å; H94-I98 PolarHBondContact O-N 2.94Å; Y95-I98 PolarHBondContact O-N 2.79Å; L96-I98 VanDerWaalsContact C-N 3.33Å; L96-I98 PolarHBondContact O-N 2.82Å; I98-M100 PolarHBondContact O-N 3.37Å; I98-N101 PolarHBondContact O-N 3.29Å; I98-L102 HydrophobicContact CG2-CD1 3.74Å; I98-L102 HydrophobicContact CG2-CG 4.42Å; I98-L102 WeakPolarHBondContact O-CB 3.31Å; I98-L102 WeakPolarHBondContact O-CG 3.34Å; I98-L102 PolarHBondContact O-N 3.45Å
99	C	65	Low	63.6	Low	9 Å²	9	39.5 Å²	39.5	6%	0.061	20%	0.2	C	C	.	.	H	α-helix	trans	-60.3	-45.7	178.9	-70	0	0	0	0	112.6	Y95 L96 L102 I103 C199	Y95-C99 PolarHBondContact O-N 3.09Å; Y95-C99 PolarHBondContact O-SG 3.4Å; L96-C99 PolarHBondContact O-N 3.42Å; C99-L102 PolarHBondContact O-N 2.91Å; C99-I103 WeakPolarHBondContact O-CG1 3.36Å; C99-I103 PolarHBondContact O-N 3.3Å; C99-C199 VanDerWaalsContact SG-CA 3.52Å; C99-C199 PolarHBondContact SG-O 2.85Å
100	M	68.8	Low	63.7	Low	17 Å²	17	32.8 Å²	32.8	8%	0.084	18%	0.175	C	C	.	.	H	α-helix	trans	-67.1	-41.3	-179.9	-68.5	-55.5	-54.9	0	0	111.7	V74 L77 T78 L96 A97 I98 L102 I103 T104	V74-M100 HydrophobicContact CG2-CE 3.62Å; L77-M100 HydrophobicContact CB-CE 3.41Å; L77-M100 VanDerWaalsContact CB-CE 3.41Å; L77-M100 HydrophobicContact CD1-CE 3.95Å; L77-M100 HydrophobicContact CG-CE 4.33Å; T78-M100 PolarHBondContact OG1-O 2.94Å; T78-M100 VanDerWaalsContact OG1-O 3.04Å; L96-M100 HydrophobicContact CD1-CG 4.04Å; L96-M100 HydrophobicContact CG-CG 4.2Å; L96-M100 WeakPolarHBondContact O-CB 3.44Å; L96-M100 VanDerWaalsContact O-CG 3.24Å; L96-M100 WeakPolarHBondContact O-CG 3.03Å; L96-M100 PolarHBondContact O-N 3.2Å; A97-M100 PolarHBondContact O-N 3.25Å; I98-M100 PolarHBondContact O-N 3.37Å; M100-L102 VanDerWaalsContact C-N 3.32Å; M100-L102 PolarHBondContact O-N 2.92Å; M100-I103 PolarHBondContact O-N 2.67Å; M100-I103 HydrophobicContact SD-CD1 4.4Å; M100-T104 WeakPolarHBondContact O-CB 3.34Å; M100-T104 PolarHBondContact O-N 2.82Å; M100-T104 PolarHBondContact O-OG1 3.17Å
101	N	62.6	Low	64.1	Low	64 Å²	64	31.4 Å²	31.4	34%	0.342	17%	0.169	S	C	.	.	H	α-helix	trans	-60.2	-42	172.7	-81.2	-51.7	0	0	0	111.5	T78 A97 I98 T104 M105	T78-N101 HydrophobicContact CG2-CB 4.3Å; T78-N101 WeakPolarHBondContact CG2-OD1 3.43Å; A97-N101 WeakPolarHBondContact O-CB 3.29Å; A97-N101 VanDerWaalsContact O-CG 3.22Å; A97-N101 PolarHBondContact O-N 3.17Å; A97-N101 PolarHBondContact O-ND2 2.95Å; I98-N101 PolarHBondContact O-N 3.29Å; N101-T104 PolarHBondContact O-N 3.31Å; N101-M105 WeakPolarHBondContact O-CB 3.49Å; N101-M105 PolarHBondContact O-N 3.13Å
102	L	65.3	Low	64.3	Low	30 Å²	30	33.5 Å²	33.5	16%	0.157	18%	0.179	C	C	.	.	H	α-helix	trans	-66.3	-46.2	177.7	-74.2	170.2	0	0	0	112.2	I98 C99 M100 T104 M105 F106 L180 L184 L203	I98-L102 HydrophobicContact CG2-CD1 3.74Å; I98-L102 HydrophobicContact CG2-CG 4.42Å; I98-L102 WeakPolarHBondContact O-CB 3.31Å; I98-L102 WeakPolarHBondContact O-CG 3.34Å; I98-L102 PolarHBondContact O-N 3.45Å; C99-L102 PolarHBondContact O-N 2.91Å; M100-L102 VanDerWaalsContact C-N 3.32Å; M100-L102 PolarHBondContact O-N 2.92Å; L102-T104 VanDerWaalsContact C-N 3.29Å; L102-T104 PolarHBondContact O-N 3.08Å; L102-M105 HydrophobicContact CD2-CE 4.44Å; L102-M105 PolarHBondContact O-N 3.11Å; L102-F106 WeakPolarHBondContact O-CD2 3.37Å; L102-F106 PolarHBondContact O-N 2.73Å; L102-L180 HydrophobicContact CB-CD2 3.56Å; L102-L180 HydrophobicContact CD1-CD1 4.43Å; L102-L180 HydrophobicContact CD1-CD2 3.72Å; L102-L180 HydrophobicContact CD2-CD1 4.15Å; L102-L180 HydrophobicContact CD2-CD2 3.94Å; L102-L180 HydrophobicContact CG-CD2 3.91Å; L102-L184 HydrophobicContact CD1-CD1 4.17Å; L102-L203 HydrophobicContact CD1-CD1 4.47Å
103	I	66.1	Low	64.1	Low	23 Å²	23	34.6 Å²	34.6	12%	0.118	19%	0.189	C	C	.	.	H	α-helix	trans	-58.6	-45.6	173.5	-69	160.5	0	0	0	110	V74 C99 M100 M105 F106 V107 I177 L203 I206	V74-I103 HydrophobicContact CG2-CG2 4.04Å; C99-I103 WeakPolarHBondContact O-CG1 3.36Å; C99-I103 PolarHBondContact O-N 3.3Å; M100-I103 PolarHBondContact O-N 2.67Å; M100-I103 HydrophobicContact SD-CD1 4.4Å; I103-M105 PolarHBondContact O-N 3.34Å; I103-F106 PolarHBondContact O-N 3.08Å; I103-V107 HydrophobicContact CG2-CG2 4.16Å; I103-V107 WeakPolarHBondContact O-CG2 3.41Å; I103-V107 PolarHBondContact O-N 3.09Å; I103-I177 HydrophobicContact CG2-CD1 4.49Å; I103-L203 HydrophobicContact CD1-CD2 3.85Å; I103-L203 HydrophobicContact CG1-CD2 3.75Å; I103-I206 HydrophobicContact CD1-CD1 4.26Å
104	T	67.1	Low	64	Low	7 Å²	7	36.1 Å²	36.1	4%	0.043	20%	0.196	C	C	.	.	H	α-helix	trans	-63.6	-39.9	-179.5	-69.8	0	0	0	0	112.7	M37 Y75 T78 M100 N101 L102 F106 V107 A108	M37-T104 HydrophobicContact CE-CG2 3.4Å; M37-T104 VanDerWaalsContact CE-CG2 3.4Å; Y75-T104 HydrophobicContact CD1-CG2 3.34Å; Y75-T104 HydrophobicContact CE1-CG2 3.67Å; Y75-T104 HydrophobicContact CG-CG2 4.42Å; T78-T104 WeakPolarHBondContact CB-OG1 3.39Å; T78-T104 HydrophobicContact CG2-CG2 4.18Å; T78-T104 PolarHBondContact OG1-OG1 3.26Å; M100-T104 WeakPolarHBondContact O-CB 3.34Å; M100-T104 PolarHBondContact O-N 2.82Å; M100-T104 PolarHBondContact O-OG1 3.17Å; N101-T104 PolarHBondContact O-N 3.31Å; L102-T104 VanDerWaalsContact C-N 3.29Å; L102-T104 PolarHBondContact O-N 3.08Å; T104-F106 VanDerWaalsContact C-N 3.27Å; T104-F106 PolarHBondContact O-N 3.49Å; T104-V107 PolarHBondContact O-N 3.12Å; T104-A108 WeakPolarHBondContact O-CB 3.47Å; T104-A108 PolarHBondContact O-N 3.15Å
105	M	68.7	Low	64	Low	117 Å²	117	36.9 Å²	36.9	58%	0.576	20%	0.201	S	C	*	.	H	α-helix	trans	-58.1	-42.7	174.4	-175.4	-170.3	-58.9	0	0	110.9	N101 L102 I103 A109	N101-M105 WeakPolarHBondContact O-CB 3.49Å; N101-M105 PolarHBondContact O-N 3.13Å; L102-M105 HydrophobicContact CD2-CE 4.44Å; L102-M105 PolarHBondContact O-N 3.11Å; I103-M105 PolarHBondContact O-N 3.34Å; M105-A109 VanDerWaalsContact O-CB 3.3Å; M105-A109 WeakPolarHBondContact O-CB 3.47Å; M105-A109 PolarHBondContact O-N 2.86Å
106	F	66	Low	63.6	Low	34 Å²	34	38 Å²	38	15%	0.149	21%	0.214	C	C	.	.	H	α-helix	trans	-75.2	-38.1	178.5	-68.6	-51.4	0	0	0	114.3	L102 I103 T104 A108 A109 G110 V173 M176 I177 L180	L102-F106 WeakPolarHBondContact O-CD2 3.37Å; L102-F106 PolarHBondContact O-N 2.73Å; I103-F106 PolarHBondContact O-N 3.08Å; T104-F106 VanDerWaalsContact C-N 3.27Å; T104-F106 PolarHBondContact O-N 3.49Å; F106-A108 VanDerWaalsContact C-N 3.27Å; F106-A108 PolarHBondContact O-N 3.48Å; F106-A109 PolarHBondContact O-N 3.37Å; F106-G110 PolarHBondContact O-N 2.89Å; F106-V173 HydrophobicContact CB-CG1 4.35Å; F106-M176 HydrophobicContact CB-CB 4.14Å; F106-M176 HydrophobicContact CB-SD 4.41Å; F106-M176 HydrophobicContact CD1-CB 3.31Å; F106-M176 HydrophobicContact CD1-CG 3.87Å; F106-M176 HydrophobicContact CD1-SD 3.53Å; F106-M176 VanDerWaalsContact CD1-SD 3.53Å; F106-M176 HydrophobicContact CD2-CB 4.29Å; F106-M176 HydrophobicContact CE1-CB 3.59Å; F106-M176 HydrophobicContact CE1-CG 4.14Å; F106-M176 HydrophobicContact CE1-SD 4.19Å; F106-M176 HydrophobicContact CE2-CB 4.49Å; F106-M176 HydrophobicContact CG-CB 3.67Å; F106-M176 HydrophobicContact CG-SD 4.35Å; F106-M176 HydrophobicContact CZ-CB 4.18Å; F106-I177 HydrophobicContact CB-CG1 4.36Å; F106-I177 HydrophobicContact CD2-CG1 3.96Å; F106-L180 HydrophobicContact CD2-CD2 4.31Å; F106-L180 HydrophobicContact CE2-CB 3.44Å; F106-L180 VanDerWaalsContact CE2-CB 3.44Å; F106-L180 HydrophobicContact CE2-CD1 4.45Å; F106-L180 HydrophobicContact CE2-CD2 3.46Å; F106-L180 VanDerWaalsContact CE2-CD2 3.46Å; F106-L180 HydrophobicContact CE2-CG 3.92Å; F106-L180 HydrophobicContact CZ-CB 3.7Å; F106-L180 HydrophobicContact CZ-CD2 4.29Å; F106-L180 HydrophobicContact CZ-CG 4.36Å
107	V	66.9	Low	63	Low	3 Å²	3	43 Å²	43	2%	0.018	24%	0.235	C	C	.	.	H	α-helix	trans	-60.8	-42.9	171.8	169.2	0	0	0	0	110.1	I71 T72 V74 Y75 I103 T104 G110 A111 V173	I71-V107 HydrophobicContact CB-CG1 4.32Å; I71-V107 HydrophobicContact CD1-CG2 3.91Å; I71-V107 HydrophobicContact CG1-CG1 3.96Å; I71-V107 HydrophobicContact CG1-CG2 3.74Å; I71-V107 HydrophobicContact CG2-CG1 3.88Å; T72-V107 HydrophobicContact CG2-CG1 4.06Å; V74-V107 HydrophobicContact CG1-CB 3.92Å; V74-V107 HydrophobicContact CG1-CG1 3.84Å; V74-V107 HydrophobicContact CG1-CG2 4.03Å; Y75-V107 HydrophobicContact CE1-CG1 4.44Å; I103-V107 HydrophobicContact CG2-CG2 4.16Å; I103-V107 WeakPolarHBondContact O-CG2 3.41Å; I103-V107 PolarHBondContact O-N 3.09Å; T104-V107 PolarHBondContact O-N 3.12Å; V107-G110 PolarHBondContact O-N 3.5Å; V107-A111 WeakPolarHBondContact O-CB 3.31Å; V107-A111 PolarHBondContact O-N 3.43Å; V107-V173 HydrophobicContact CG2-CG1 3.81Å
108	A	66	Low	62.7	Low	33 Å²	33	44.3 Å²	44.3	27%	0.273	24%	0.242	S	C	.	.	H	α-helix	trans	-65.9	-41.4	175.9	0	0	0	0	0	112.3	Y75 T104 F106 L112	Y75-A108 HydrophobicContact CE1-CB 4.03Å; Y75-A108 VanDerWaalsContact OH-CA 3.24Å; Y75-A108 WeakPolarHBondContact OH-CA 3.17Å; Y75-A108 VanDerWaalsContact OH-CB 3.27Å; Y75-A108 WeakPolarHBondContact OH-CB 3.36Å; T104-A108 WeakPolarHBondContact O-CB 3.47Å; T104-A108 PolarHBondContact O-N 3.15Å; F106-A108 VanDerWaalsContact C-N 3.27Å; F106-A108 PolarHBondContact O-N 3.48Å; A108-L112 WeakPolarHBondContact O-CB 3.4Å; A108-L112 PolarHBondContact O-N 3.06Å
109	A	64.8	Low	62	Low	33 Å²	33	46.4 Å²	46.4	27%	0.273	25%	0.253	S	S	.	.	H	α-helix	trans	-64.4	-45.1	175.8	0	0	0	0	0	111.5	M105 F106 L112 V113 M176	M105-A109 VanDerWaalsContact O-CB 3.3Å; M105-A109 WeakPolarHBondContact O-CB 3.47Å; M105-A109 PolarHBondContact O-N 2.86Å; F106-A109 PolarHBondContact O-N 3.37Å; A109-L112 PolarHBondContact O-N 3.31Å; A109-V113 VanDerWaalsContact O-CG2 3.25Å; A109-V113 WeakPolarHBondContact O-CG2 3.42Å; A109-V113 PolarHBondContact O-N 3.36Å; A109-M176 HydrophobicContact CB-SD 4.19Å
110	G	62.6	Low	60.9	Low	1 Å²	1	50.2 Å²	50.2	1%	0.01	27%	0.272	C	S	.	.	H	α-helix	trans	-61.1	-50.7	174.5	0	0	0	0	0	111.6	F106 V107 L112 V113 F114	F106-G110 PolarHBondContact O-N 2.89Å; V107-G110 PolarHBondContact O-N 3.5Å; G110-L112 VanDerWaalsContact C-N 3.32Å; G110-L112 PolarHBondContact O-N 2.97Å; G110-V113 WeakPolarHBondContact O-CB 3.48Å; G110-V113 PolarHBondContact O-N 3.2Å; G110-V113 VanDerWaalsContact O-N 3.14Å; G110-F114 WeakPolarHBondContact O-CD2 3.2Å; G110-F114 PolarHBondContact O-N 2.91Å
111	A	63.8	Low	59.9	Low	5 Å²	5	52.3 Å²	52.3	4%	0.041	29%	0.286	C	S	.	.	H	α-helix	trans	-57.1	-44.8	177.1	0	0	0	0	0	111.7	T72 V107 V113 F114 D115	T72-A111 HydrophobicContact CG2-CB 3.82Å; V107-A111 WeakPolarHBondContact O-CB 3.31Å; V107-A111 PolarHBondContact O-N 3.43Å; A111-V113 PolarHBondContact O-N 3.38Å; A111-F114 PolarHBondContact O-N 3.47Å; A111-D115 VanDerWaalsContact O-CB 3.27Å; A111-D115 WeakPolarHBondContact O-CB 3.44Å; A111-D115 PolarHBondContact O-N 2.62Å
112	L	62.7	Low	59	Low	113 Å²	113	54.4 Å²	54.4	59%	0.592	30%	0.296	S	S	*	.	H	α-helix	trans	-59.5	-45.6	175.5	-178.6	69.7	0	0	0	111.9	A108 A109 G110 D115 S116	A108-L112 WeakPolarHBondContact O-CB 3.4Å; A108-L112 PolarHBondContact O-N 3.06Å; A109-L112 PolarHBondContact O-N 3.31Å; G110-L112 VanDerWaalsContact C-N 3.32Å; G110-L112 PolarHBondContact O-N 2.97Å; L112-D115 PolarHBondContact O-N 3.04Å; L112-S116 VanDerWaalsContact O-CB 3.28Å; L112-S116 WeakPolarHBondContact O-CB 3.18Å; L112-S116 PolarHBondContact O-N 3.36Å; L112-S116 PolarHBondContact O-OG 2.9Å
113	V	56.9	Low	58	Low	62 Å²	62	55.8 Å²	55.8	38%	0.376	31%	0.308	S	S	.	.	H	α-helix	trans	-59.3	-47.9	176.8	166.9	0	0	0	0	110.5	A109 G110 A111 S116 F117	A109-V113 VanDerWaalsContact O-CG2 3.25Å; A109-V113 WeakPolarHBondContact O-CG2 3.42Å; A109-V113 PolarHBondContact O-N 3.36Å; G110-V113 WeakPolarHBondContact O-CB 3.48Å; G110-V113 PolarHBondContact O-N 3.2Å; G110-V113 VanDerWaalsContact O-N 3.14Å; A111-V113 PolarHBondContact O-N 3.38Å; V113-S116 WeakPolarHBondContact O-CB 3.43Å; V113-S116 PolarHBondContact O-N 3.12Å; V113-F117 HydrophobicContact CG1-CD2 3.84Å; V113-F117 HydrophobicContact CG1-CE2 3.51Å; V113-F117 WeakPolarHBondContact O-CD2 3.27Å; V113-F117 PolarHBondContact O-N 3.49Å
114	F	58.7	Low	57.2	Low	33 Å²	33	63 Å²	63	15%	0.145	34%	0.341	C	S	.	.	H	α-helix	trans	-70.7	-37	-179.3	-69.6	-64.7	0	0	0	113.4	N67 H69 G110 A111 S116 F117 N118 T169 P172	N67-F114 VanDerWaalsContact ND2-CB 3.3Å; N67-F114 WeakPolarHBondContact ND2-CB 3.25Å; N67-F114 PolarHBondContact ND2-O 3.36Å; H69-F114 AromaticContact CE1-CD2 3.91Å; G110-F114 WeakPolarHBondContact O-CD2 3.2Å; G110-F114 PolarHBondContact O-N 2.91Å; A111-F114 PolarHBondContact O-N 3.47Å; F114-S116 VanDerWaalsContact C-N 3.28Å; F114-F117 WeakPolarHBondContact O-CB 2.81Å; F114-F117 PolarHBondContact O-N 2.93Å; F114-N118 PolarHBondContact O-N 3.05Å; F114-T169 HydrophobicContact CE1-CG2 4.36Å; F114-T169 WeakPolarHBondContact CE2-O 3.38Å; F114-T169 HydrophobicContact CZ-CG2 4.49Å; F114-T169 WeakPolarHBondContact CZ-O 3.41Å; F114-P172 HydrophobicContact CE2-CG 4.26Å; F114-P172 HydrophobicContact CZ-CG 3.73Å
115	D	60.3	Low	56.1	Low	64 Å²	64	68.9 Å²	68.9	34%	0.342	37%	0.372	S	S	.	.	H	α-helix	trans	-67.2	-35.1	174.7	-70	-13	0	0	0	110.4	N67 H69 A111 L112 N118 L119	N67-D115 VanDerWaalsContact CB-OD1 3.28Å; N67-D115 WeakPolarHBondContact CB-OD1 3.43Å; N67-D115 PolarHBondContact ND2-N 2.9Å; N67-D115 PolarHBondContact ND2-OD1 3.5Å; H69-D115 IonicContact CD2-OD1 3.55Å; H69-D115 PolarHBondContact CD2-OD1 2.94Å; H69-D115 IonicContact CD2-OD2 2.92Å; H69-D115 IonicContact NE2-OD1 3.49Å; H69-D115 PolarHBondContact NE2-OD1 2.97Å; H69-D115 VanDerWaalsContact NE2-OD1 3.12Å; A111-D115 VanDerWaalsContact O-CB 3.27Å; A111-D115 WeakPolarHBondContact O-CB 3.44Å; A111-D115 PolarHBondContact O-N 2.62Å; L112-D115 PolarHBondContact O-N 3.04Å; D115-N118 PolarHBondContact O-N 3.28Å; D115-L119 WeakPolarHBondContact O-CB 3.5Å; D115-L119 VanDerWaalsContact O-CG 3.29Å; D115-L119 WeakPolarHBondContact O-CG 3.06Å; D115-L119 PolarHBondContact O-N 3.4Å
116	S	52.3	Low	54.7	Low	57 Å²	57	68.3 Å²	68.3	40%	0.399	38%	0.38	S	S	.	.	H	α-helix	trans	-63.6	-42.2	171.6	-56.1	0	0	0	0	111.5	L112 V113 F114 N118 L119 D120	L112-S116 VanDerWaalsContact O-CB 3.28Å; L112-S116 WeakPolarHBondContact O-CB 3.18Å; L112-S116 PolarHBondContact O-N 3.36Å; L112-S116 PolarHBondContact O-OG 2.9Å; V113-S116 WeakPolarHBondContact O-CB 3.43Å; V113-S116 PolarHBondContact O-N 3.12Å; F114-S116 VanDerWaalsContact C-N 3.28Å; S116-N118 PolarHBondContact O-N 3.23Å; S116-L119 PolarHBondContact O-N 3.28Å; S116-D120 PolarHBondContact O-N 2.96Å
117	F	51.5	Low	53.7	Low	123 Å²	123	71.5 Å²	71.5	54%	0.539	41%	0.406	S	S	.	.	H	α-helix	trans	-61.6	-40.9	173.6	-80.8	-63.7	0	0	0	113	V113 F114 D120 V121	V113-F117 HydrophobicContact CG1-CD2 3.84Å; V113-F117 HydrophobicContact CG1-CE2 3.51Å; V113-F117 WeakPolarHBondContact O-CD2 3.27Å; V113-F117 PolarHBondContact O-N 3.49Å; F114-F117 WeakPolarHBondContact O-CB 2.81Å; F114-F117 PolarHBondContact O-N 2.93Å; F117-D120 WeakPolarHBondContact O-CB 3.16Å; F117-D120 PolarHBondContact O-N 3.35Å; F117-V121 WeakPolarHBondContact O-CG2 3.17Å; F117-V121 PolarHBondContact O-N 3.49Å; F117-V121 VanDerWaalsContact O-N 3.11Å
118	N	55.7	Low	52.5	Low	34 Å²	34	77 Å²	77	18%	0.182	44%	0.444	C	S	.	.	H	α-helix	trans	-67	-38.3	176.1	-75	-17.8	0	0	0	111.9	N67 F114 D115 S116 D120 V121 I122	N67-N118 WeakPolarHBondContact CB-ND2 3.46Å; N67-N118 PolarHBondContact ND2-ND2 3.16Å; F114-N118 PolarHBondContact O-N 3.05Å; D115-N118 PolarHBondContact O-N 3.28Å; S116-N118 PolarHBondContact O-N 3.23Å; N118-D120 VanDerWaalsContact C-N 3.34Å; N118-V121 PolarHBondContact O-N 3.41Å; N118-I122 VanDerWaalsContact O-CG1 3.31Å; N118-I122 WeakPolarHBondContact O-CG1 3.41Å; N118-I122 PolarHBondContact O-N 2.89Å
119	L	49.4	Very low	51.6	Low	112 Å²	112	80 Å²	80	59%	0.586	46%	0.455	S	S	*	.	H	α-helix	trans	-66.1	-36.9	174.6	-72.8	171.3	0	0	0	111.7	D115 S116 I122 S123	D115-L119 WeakPolarHBondContact O-CB 3.5Å; D115-L119 VanDerWaalsContact O-CG 3.29Å; D115-L119 WeakPolarHBondContact O-CG 3.06Å; D115-L119 PolarHBondContact O-N 3.4Å; S116-L119 PolarHBondContact O-N 3.28Å; L119-I122 PolarHBondContact O-N 3.47Å; L119-S123 VanDerWaalsContact O-CB 3.23Å; L119-S123 WeakPolarHBondContact O-CB 3.31Å; L119-S123 PolarHBondContact O-N 2.93Å; L119-S123 PolarHBondContact O-OG 2.9Å
120	D	42.8	Very low	50.5	Low	89 Å²	89	85.1 Å²	85.1	48%	0.476	48%	0.478	S	S	.	.	H	α-helix	trans	-59	-47.2	172.4	-97.3	-1.5	0	0	0	111	S116 F117 N118 I122 S123 E124	S116-D120 PolarHBondContact O-N 2.96Å; F117-D120 WeakPolarHBondContact O-CB 3.16Å; F117-D120 PolarHBondContact O-N 3.35Å; N118-D120 VanDerWaalsContact C-N 3.34Å; D120-I122 VanDerWaalsContact C-N 3.31Å; D120-I122 PolarHBondContact O-N 3.22Å; D120-S123 WeakPolarHBondContact CA-OG 3.28Å; D120-S123 PolarHBondContact O-N 2.7Å; D120-S123 VanDerWaalsContact O-N 3.13Å; D120-S123 PolarHBondContact O-OG 3.28Å; D120-E124 PolarHBondContact O-N 3.36Å
121	V	47.9	Very low	49.4	Very low	61 Å²	61	89.4 Å²	89.4	37%	0.37	51%	0.513	S	S	.	.	H	α-helix	trans	-60.6	-37.2	176.1	170.4	0	0	0	0	112.4	L62 F117 N118	L62-V121 HydrophobicContact CD2-CG1 3.53Å; L62-V121 HydrophobicContact CD2-CG2 4.18Å; L62-V121 HydrophobicContact CG-CG1 4.11Å; F117-V121 WeakPolarHBondContact O-CG2 3.17Å; F117-V121 PolarHBondContact O-N 3.49Å; F117-V121 VanDerWaalsContact O-N 3.11Å; N118-V121 PolarHBondContact O-N 3.41Å
122	I	44.6	Very low	48.3	Very low	109 Å²	109	94.9 Å²	94.9	56%	0.559	54%	0.541	S	S	*	.	H	α-helix	trans	-75.8	-32.7	176.7	-66.5	166.2	0	0	0	111.1	N118 L119 D120 L125	N118-I122 VanDerWaalsContact O-CG1 3.31Å; N118-I122 WeakPolarHBondContact O-CG1 3.41Å; N118-I122 PolarHBondContact O-N 2.89Å; L119-I122 PolarHBondContact O-N 3.47Å; D120-I122 VanDerWaalsContact C-N 3.31Å; D120-I122 PolarHBondContact O-N 3.22Å; I122-L125 WeakPolarHBondContact O-CB 3.45Å; I122-L125 PolarHBondContact O-N 3.15Å; I122-L125 VanDerWaalsContact O-N 3.1Å
123	S	42.5	Very low	47.2	Very low	58 Å²	58	94 Å²	94	41%	0.406	54%	0.536	S	S	.	.	H	α-helix	trans	-74.7	-22.4	-176.7	78.7	0	0	0	0	114.1	L119 D120 L125	L119-S123 VanDerWaalsContact O-CB 3.23Å; L119-S123 WeakPolarHBondContact O-CB 3.31Å; L119-S123 PolarHBondContact O-N 2.93Å; L119-S123 PolarHBondContact O-OG 2.9Å; D120-S123 WeakPolarHBondContact CA-OG 3.28Å; D120-S123 PolarHBondContact O-N 2.7Å; D120-S123 VanDerWaalsContact O-N 3.13Å; D120-S123 PolarHBondContact O-OG 3.28Å; S123-L125 PolarHBondContact O-N 2.9Å
124	E	49.3	Very low	46.3	Very low	174 Å²	174	94.5 Å²	94.5	81%	0.813	55%	0.547	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.2	-10.5	168	-75.3	-172.5	153.8	0	0	112.7	D120 S126	D120-E124 PolarHBondContact O-N 3.36Å; E124-S126 PolarHBondContact O-N 3.01Å
125	L	45.1	Very low	45.3	Very low	132 Å²	132	102 Å²	102	69%	0.691	58%	0.575	S	S	*	*	S	Bend	trans	-84.1	92.6	169.7	-133.9	76.2	0	0	0	109.7	I122 S123 S127	I122-L125 WeakPolarHBondContact O-CB 3.45Å; I122-L125 PolarHBondContact O-N 3.15Å; I122-L125 VanDerWaalsContact O-N 3.1Å; S123-L125 PolarHBondContact O-N 2.9Å; L125-S127 PolarHBondContact O-N 3.41Å
126	S	39.9	Very low	44.4	Very low	105 Å²	105	102.1 Å²	102.1	73%	0.734	58%	0.576	S	S	*	*	S	Bend	trans	-34.1	111.4	-170.1	65.9	0	0	0	0	118.6	E124	E124-S126 PolarHBondContact O-N 3.01Å
127	S	43.6	Very low	43.9	Very low	101 Å²	101	103.6 Å²	103.6	71%	0.706	58%	0.578	S	S	*	*	S	Bend		161.5	128.2	118.2	54	0	0	0	0	112.7	L125	L125-S127 PolarHBondContact O-N 3.41Å
128	S	42.7	Very low	43.4	Very low	117 Å²	117	105 Å²	105	82%	0.818	59%	0.588	S	S	*	*			trans	108.1	63.6	168.6	-41.8	0	0	0	0	117
129	I	47.3	Very low	42.5	Very low	97 Å²	97	108.8 Å²	108.8	50%	0.497	61%	0.608	S	S	.	*			trans	-119.8	100.3	-170.3	-61.7	164.4	0	0	0	110.6	L133	I129-L133 HydrophobicContact CG2-CD1 4.19Å
130	N	41.5	Very low	42.2	Very low	141 Å²	141	107.7 Å²	107.7	75%	0.754	60%	0.603	S	S	*	*	S	Bend	trans	-153.2	-33.4	164.1	-88.1	-34	0	0	0	114.7
131	A	38.4	Very low	42.2	Very low	91 Å²	91	110.4 Å²	110.4	75%	0.752	61%	0.61	S	S	*	*	S	Bend	trans	-87.1	-30	-178.9	0	0	0	0	0	114.3	L133	A131-L133 VanDerWaalsContact C-N 3.29Å
132	I	41.6	Very low	41.8	Very low	120 Å²	120	112.7 Å²	112.7	62%	0.615	62%	0.624	S	S	*	*	H	α-helix	trans	-73	-26.6	176	-65.9	167.3	0	0	0	110.9	A134 N136	I132-A134 PolarHBondContact O-N 2.85Å; I132-N136 PolarHBondContact O-N 3.43Å
133	L	38.3	Very low	41.5	Very low	95 Å²	95	109.5 Å²	109.5	50%	0.497	62%	0.619	S	S	.	*	H	α-helix	trans	-66.8	-34.8	-177.1	-162.1	72.8	0	0	0	113.5	I129 A131 I137	I129-L133 HydrophobicContact CG2-CD1 4.19Å; A131-L133 VanDerWaalsContact C-N 3.29Å; L133-I137 VanDerWaalsContact O-CD1 3.24Å; L133-I137 WeakPolarHBondContact O-CD1 3.43Å; L133-I137 VanDerWaalsContact O-CG1 3.25Å; L133-I137 WeakPolarHBondContact O-CG1 3.26Å
134	A	39.6	Very low	41.6	Very low	72 Å²	72	110.4 Å²	110.4	60%	0.595	62%	0.618	S	S	*	*	H	α-helix	trans	-78.6	-27.2	-177.2	0	0	0	0	0	113.9	I132	I132-A134 PolarHBondContact O-N 2.85Å
135	Y	37	Very low	41.2	Very low	191 Å²	191	109.9 Å²	109.9	75%	0.749	61%	0.614	S	S	*	*	H	α-helix	trans	-86.8	-35.6	-176.5	-162.3	-95.2	0	0	0	111.8	I137	Y135-I137 VanDerWaalsContact C-N 3.28Å; Y135-I137 PolarHBondContact O-N 3.21Å
136	N	40.6	Very low	40.9	Very low	66 Å²	66	107.3 Å²	107.3	35%	0.353	61%	0.611	S	S	.	*	H	α-helix	trans	-63.6	-28.6	173.4	-75.8	-9.1	0	0	0	112.9	I132 M138 D139 I140	I132-N136 PolarHBondContact O-N 3.43Å; N136-M138 VanDerWaalsContact C-N 3.34Å; N136-M138 PolarHBondContact O-N 3.29Å; N136-D139 PolarHBondContact O-N 3.13Å; N136-I140 HydrophobicContact CB-CD1 4.18Å; N136-I140 VanDerWaalsContact O-CB 3.24Å; N136-I140 WeakPolarHBondContact O-CB 3.42Å; N136-I140 WeakPolarHBondContact O-CD1 3.36Å; N136-I140 WeakPolarHBondContact O-CG1 3.32Å; N136-I140 PolarHBondContact O-N 3.29Å
137	I	42.2	Very low	41.2	Very low	88 Å²	88	106.8 Å²	106.8	45%	0.451	60%	0.6	S	S	.	*	H	α-helix	trans	-63.2	-33.3	-178.5	-71.5	165.9	0	0	0	113.2	L133 Y135 F141	L133-I137 VanDerWaalsContact O-CD1 3.24Å; L133-I137 WeakPolarHBondContact O-CD1 3.43Å; L133-I137 VanDerWaalsContact O-CG1 3.25Å; L133-I137 WeakPolarHBondContact O-CG1 3.26Å; Y135-I137 VanDerWaalsContact C-N 3.28Å; Y135-I137 PolarHBondContact O-N 3.21Å; I137-F141 HydrophobicContact CG2-CE2 4.35Å; I137-F141 VanDerWaalsContact O-CD2 3.27Å; I137-F141 WeakPolarHBondContact O-CD2 3.36Å
138	M	40.6	Very low	41.2	Very low	151 Å²	151	104.6 Å²	104.6	74%	0.744	59%	0.588	S	S	*	*	H	α-helix	trans	-79.3	-33.4	179.9	-81.8	-82.1	-77.2	0	0	113.4	N136	N136-M138 VanDerWaalsContact C-N 3.34Å; N136-M138 PolarHBondContact O-N 3.29Å
139	D	38.3	Very low	41.3	Very low	114 Å²	114	105 Å²	105	61%	0.61	58%	0.579	S	S	*	*	H	α-helix	trans	-77.2	-31.9	177.7	-125.4	-8.4	0	0	0	111.6	N136 F141 T142 G143	N136-D139 PolarHBondContact O-N 3.13Å; D139-F141 VanDerWaalsContact C-N 3.33Å; D139-F141 PolarHBondContact O-N 3.06Å; D139-T142 PolarHBondContact O-N 2.88Å; D139-G143 PolarHBondContact O-N 3.3Å
140	I	43.3	Very low	41	Very low	90 Å²	90	102 Å²	102	46%	0.462	57%	0.573	S	S	.	*	H	α-helix	trans	-55.8	-41.2	170.5	-77.4	166.8	0	0	0	111.6	N136 T142 L144	N136-I140 HydrophobicContact CB-CD1 4.18Å; N136-I140 VanDerWaalsContact O-CB 3.24Å; N136-I140 WeakPolarHBondContact O-CB 3.42Å; N136-I140 WeakPolarHBondContact O-CD1 3.36Å; N136-I140 WeakPolarHBondContact O-CG1 3.32Å; N136-I140 PolarHBondContact O-N 3.29Å; I140-T142 PolarHBondContact O-N 3.4Å; I140-L144 HydrophobicContact CG2-CD1 3.38Å; I140-L144 HydrophobicContact CG2-CG 4.03Å; I140-L144 WeakPolarHBondContact O-CB 3.44Å; I140-L144 VanDerWaalsContact O-CD1 3.29Å; I140-L144 WeakPolarHBondContact O-CD1 3.24Å; I140-L144 WeakPolarHBondContact O-CG 3.07Å; I140-L144 PolarHBondContact O-N 3.47Å
141	F	42.6	Very low	41.1	Very low	146 Å²	146	100 Å²	100	64%	0.64	56%	0.562	S	S	*	*	H	α-helix	trans	-68.6	-29.1	-178.6	-88.4	-77.2	0	0	0	114.8	I137 D139	I137-F141 HydrophobicContact CG2-CE2 4.35Å; I137-F141 VanDerWaalsContact O-CD2 3.27Å; I137-F141 WeakPolarHBondContact O-CD2 3.36Å; D139-F141 VanDerWaalsContact C-N 3.33Å; D139-F141 PolarHBondContact O-N 3.06Å
142	T	38.5	Very low	41.3	Very low	108 Å²	108	99.8 Å²	99.8	66%	0.663	56%	0.56	S	S	*	*	H	α-helix	trans	-86.8	-34.3	-177.2	-40.4	0	0	0	0	111.6	D139 I140	D139-T142 PolarHBondContact O-N 2.88Å; I140-T142 PolarHBondContact O-N 3.4Å
143	G	38	Very low	41.2	Very low	43 Å²	43	98.6 Å²	98.6	44%	0.443	56%	0.559	S	S	.	*	H	α-helix	trans	-68.8	-35	166.3	0	0	0	0	0	113.4	D139 F145 A146 L147	D139-G143 PolarHBondContact O-N 3.3Å; G143-F145 VanDerWaalsContact C-N 3.28Å; G143-F145 PolarHBondContact O-N 3.23Å; G143-A146 PolarHBondContact O-N 3.49Å; G143-L147 VanDerWaalsContact O-CB 3.22Å; G143-L147 WeakPolarHBondContact O-CB 3.3Å; G143-L147 PolarHBondContact O-N 3.38Å
144	L	44.5	Very low	41.3	Very low	76 Å²	76	99.4 Å²	99.4	40%	0.398	56%	0.563	S	S	.	*	H	α-helix	trans	-61.2	-28.9	176.9	-84.7	167.9	0	0	0	113.6	I140 L147 A148	I140-L144 HydrophobicContact CG2-CD1 3.38Å; I140-L144 HydrophobicContact CG2-CG 4.03Å; I140-L144 WeakPolarHBondContact O-CB 3.44Å; I140-L144 VanDerWaalsContact O-CD1 3.29Å; I140-L144 WeakPolarHBondContact O-CD1 3.24Å; I140-L144 WeakPolarHBondContact O-CG 3.07Å; I140-L144 PolarHBondContact O-N 3.47Å; L144-L147 HydrophobicContact CD2-CD2 4.35Å; L144-A148 WeakPolarHBondContact O-CB 3.18Å; L144-A148 PolarHBondContact O-N 2.78Å
145	F	41.4	Very low	41.1	Very low	164 Å²	164	107.6 Å²	107.6	72%	0.719	58%	0.578	S	S	*	*	H	α-helix	trans	-75.6	-35.5	178.8	-158	-97.2	0	0	0	112.8	G143	G143-F145 VanDerWaalsContact C-N 3.28Å; G143-F145 PolarHBondContact O-N 3.23Å
146	A	39.3	Very low	41.2	Very low	77 Å²	77	102.7 Å²	102.7	64%	0.636	56%	0.564	S	S	*	*	H	α-helix	trans	-77.4	-33.8	172.7	0	0	0	0	0	112	G143	G143-A146 PolarHBondContact O-N 3.49Å
147	L	45.7	Very low	41.1	Very low	95 Å²	95	101.8 Å²	101.8	50%	0.497	57%	0.571	S	S	.	*	H	α-helix	trans	-69.6	-33.7	173.2	-164	77.1	0	0	0	112.1	G143 L144 I149 G150 L151	G143-L147 VanDerWaalsContact O-CB 3.22Å; G143-L147 WeakPolarHBondContact O-CB 3.3Å; G143-L147 PolarHBondContact O-N 3.38Å; L144-L147 HydrophobicContact CD2-CD2 4.35Å; L147-I149 VanDerWaalsContact C-N 3.34Å; L147-I149 PolarHBondContact O-N 2.93Å; L147-G150 CarbonylContact O-C 3.58Å; L147-G150 PolarHBondContact O-N 3.39Å; L147-L151 HydrophobicContact CB-CD1 4.38Å; L147-L151 HydrophobicContact CD2-CD1 3.64Å; L147-L151 HydrophobicContact CG-CD1 3.53Å; L147-L151 HydrophobicContact CG-CG 4.13Å; L147-L151 WeakPolarHBondContact O-CB 3.39Å; L147-L151 WeakPolarHBondContact O-CG 3.03Å; L147-L151 PolarHBondContact O-N 3.4Å
148	A	44.7	Very low	40.7	Very low	55 Å²	55	103.5 Å²	103.5	46%	0.455	58%	0.581	S	S	.	*	H	α-helix	trans	-64.4	-32.4	179	0	0	0	0	0	113.7	L144 A152	L144-A148 WeakPolarHBondContact O-CB 3.18Å; L144-A148 PolarHBondContact O-N 2.78Å; A148-A152 PolarHBondContact O-N 3.35Å
149	I	45	Very low	40.5	Very low	124 Å²	124	101.3 Å²	101.3	64%	0.636	58%	0.58	S	S	*	*	H	α-helix	trans	-76.9	-31.6	176	-62.9	176.3	0	0	0	111.1	L147	L147-I149 VanDerWaalsContact C-N 3.34Å; L147-I149 PolarHBondContact O-N 2.93Å
150	G	39.6	Very low	40.5	Very low	36 Å²	36	98.4 Å²	98.4	37%	0.371	57%	0.573	S	S	.	*	H	α-helix	trans	-82.3	-24.7	173.1	0	0	0	0	0	115	L147 T153	L147-G150 CarbonylContact O-C 3.58Å; L147-G150 PolarHBondContact O-N 3.39Å; G150-T153 PolarHBondContact O-OG1 3.29Å; G150-T153 VanDerWaalsContact O-OG1 3.09Å
151	L	44.4	Very low	40.2	Very low	99 Å²	99	101.4 Å²	101.4	52%	0.518	58%	0.578	S	S	.	*	H	α-helix	trans	-78.1	-24.5	174.3	-88.3	161.1	0	0	0	112.4	L147 T153	L147-L151 HydrophobicContact CB-CD1 4.38Å; L147-L151 HydrophobicContact CD2-CD1 3.64Å; L147-L151 HydrophobicContact CG-CD1 3.53Å; L147-L151 HydrophobicContact CG-CG 4.13Å; L147-L151 WeakPolarHBondContact O-CB 3.39Å; L147-L151 WeakPolarHBondContact O-CG 3.03Å; L147-L151 PolarHBondContact O-N 3.4Å; L151-T153 PolarHBondContact O-N 2.87Å
152	A	41.4	Very low	39.8	Very low	85 Å²	85	102.7 Å²	102.7	70%	0.702	58%	0.58	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.3	-8.1	175.9	0	0	0	0	0	113.7	A148	A148-A152 PolarHBondContact O-N 3.35Å
153	T	41.1	Very low	39.7	Very low	96 Å²	96	101.1 Å²	101.1	59%	0.589	57%	0.566	S	S	*	*	T	Hydrogen-bonded Turn	trans	-118.2	11.4	-175.5	49.2	0	0	0	0	114.9	G150 L151	G150-T153 PolarHBondContact O-OG1 3.29Å; G150-T153 VanDerWaalsContact O-OG1 3.09Å; L151-T153 PolarHBondContact O-N 2.87Å
154	L	40.5	Very low	39.6	Very low	112 Å²	112	104.8 Å²	104.8	59%	0.586	57%	0.57	S	S	*	*			trans	-113.1	109.3	-176.2	-75.1	165.2	0	0	0	114.2
155	R	35	Very low	39.2	Very low	244 Å²	244	106.8 Å²	106.8	92%	0.921	58%	0.581	S	S	*	*			trans	-140	73.2	151.8	-82.5	-168.8	177	175.8	-0.2	109.3
156	L	38.4	Very low	39	Very low	87 Å²	87	102.3 Å²	102.3	46%	0.455	56%	0.564	S	S	.	*			trans	-143.9	141.9	169.4	-72.4	177.6	0	0	0	110.8	L230	L156-L230 HydrophobicContact CD1-CD1 3.43Å; L156-L230 VanDerWaalsContact CD1-CD1 3.43Å; L156-L230 HydrophobicContact CG-CD1 4.46Å
157	G	37.7	Very low	39.1	Very low	48 Å²	48	103.5 Å²	103.5	50%	0.495	55%	0.553	S	S	.	*			trans	-82.2	-175.4	-159.3	0	0	0	0	0	118.6	S159 A160	G157-S159 PolarHBondContact O-N 2.94Å; G157-A160 PolarHBondContact O-N 2.89Å
158	D	35.3	Very low	39.3	Very low	123 Å²	123	99.8 Å²	99.8	66%	0.658	53%	0.534	S	S	*	.	H	α-helix	trans	-66.9	-22.9	-156.4	-64.9	-40.8	0	0	0	117.2	Y162	D158-Y162 PolarHBondContact O-N 3.34Å
159	S	36.3	Very low	39.3	Very low	105 Å²	105	98.7 Å²	98.7	73%	0.734	52%	0.522	S	S	*	.	H	α-helix	trans	-79.6	-25.3	178.1	27.2	0	0	0	0	113.3	G157	G157-S159 PolarHBondContact O-N 2.94Å
160	A	38.4	Very low	39.6	Very low	54 Å²	54	93.3 Å²	93.3	45%	0.446	49%	0.494	S	S	.	.	H	α-helix	trans	-77.3	-33.6	173.2	0	0	0	0	0	111.6	G157 Y162 M163 F164	G157-A160 PolarHBondContact O-N 2.89Å; A160-Y162 PolarHBondContact O-N 2.84Å; A160-M163 CarbonylContact O-C 3.56Å; A160-M163 PolarHBondContact O-N 2.78Å; A160-F164 WeakPolarHBondContact O-CB 3.31Å; A160-F164 PolarHBondContact O-N 3.46Å
161	R	35.8	Very low	40.2	Very low	153 Å²	153	93.5 Å²	93.5	58%	0.577	49%	0.485	S	S	*	.	H	α-helix	trans	-60.9	-40.2	173.8	-101.2	177.8	166.6	-178.1	-6.4	112.9	M163 F164 L165	R161-M163 VanDerWaalsContact C-N 3.33Å; R161-F164 PolarHBondContact O-N 3.26Å; R161-L165 WeakPolarHBondContact O-CB 3.27Å; R161-L165 WeakPolarHBondContact O-CD1 3.37Å; R161-L165 PolarHBondContact O-N 2.66Å
162	Y	33.9	Very low	40.5	Very low	172 Å²	172	91.1 Å²	91.1	68%	0.675	48%	0.476	S	S	*	.	H	α-helix	trans	-68.9	-30.5	176.1	-99.6	-85.6	0	0	0	113.3	D158 A160 N166	D158-Y162 PolarHBondContact O-N 3.34Å; A160-Y162 PolarHBondContact O-N 2.84Å; Y162-N166 WeakPolarHBondContact O-CB 3.39Å; Y162-N166 PolarHBondContact O-N 2.89Å; Y162-N166 PolarHBondContact O-ND2 3.32Å
163	M	37.6	Very low	41.3	Very low	75 Å²	75	87.2 Å²	87.2	37%	0.369	44%	0.444	S	S	.	.	H	α-helix	trans	-81.3	-25	173.7	-142.7	-166.8	-51	0	0	112	A160 R161 Y167 L225	A160-M163 CarbonylContact O-C 3.56Å; A160-M163 PolarHBondContact O-N 2.78Å; R161-M163 VanDerWaalsContact C-N 3.33Å; M163-Y167 HydrophobicContact CG-CD2 4.14Å; M163-Y167 HydrophobicContact CG-CE2 3.88Å; M163-Y167 WeakPolarHBondContact O-CB 3.36Å; M163-Y167 WeakPolarHBondContact O-CD2 3.14Å; M163-L225 HydrophobicContact CE-CD1 3.68Å; M163-L225 HydrophobicContact CE-CD2 4.21Å; M163-L225 HydrophobicContact SD-CD1 3.98Å
164	F	35.2	Very low	42.3	Very low	120 Å²	120	83.5 Å²	83.5	53%	0.526	42%	0.419	S	S	.	.	H	α-helix	trans	-78.3	-56.4	175.7	-148.6	-96.6	0	0	0	109.9	A160 R161 N166 Y167 T168	A160-F164 WeakPolarHBondContact O-CB 3.31Å; A160-F164 PolarHBondContact O-N 3.46Å; R161-F164 PolarHBondContact O-N 3.26Å; F164-N166 VanDerWaalsContact C-N 3.29Å; F164-N166 PolarHBondContact O-N 3.31Å; F164-N166 VanDerWaalsContact O-N 3.16Å; F164-Y167 PolarHBondContact O-N 3.47Å; F164-T168 HydrophobicContact CD1-CG2 4.28Å; F164-T168 HydrophobicContact CE1-CG2 4.33Å; F164-T168 WeakPolarHBondContact O-CB 3.46Å; F164-T168 VanDerWaalsContact O-CG2 3.26Å; F164-T168 WeakPolarHBondContact O-CG2 3.37Å; F164-T168 PolarHBondContact O-N 3.37Å; F164-T168 PolarHBondContact O-OG1 2.93Å
165	L	36	Very low	43.1	Very low	119 Å²	119	82.7 Å²	82.7	62%	0.623	42%	0.415	S	S	*	.	H	α-helix	trans	-62.6	-26.5	-178.5	-87.2	133.6	0	0	0	115.1	R161	R161-L165 WeakPolarHBondContact O-CB 3.27Å; R161-L165 WeakPolarHBondContact O-CD1 3.37Å; R161-L165 PolarHBondContact O-N 2.66Å
166	N	37	Very low	44.4	Very low	70 Å²	70	73.9 Å²	73.9	37%	0.374	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.3	-10.7	175.7	-81.1	-60.8	0	0	0	114.2	Y162 F164	Y162-N166 WeakPolarHBondContact O-CB 3.39Å; Y162-N166 PolarHBondContact O-N 2.89Å; Y162-N166 PolarHBondContact O-ND2 3.32Å; F164-N166 VanDerWaalsContact C-N 3.29Å; F164-N166 PolarHBondContact O-N 3.31Å; F164-N166 VanDerWaalsContact O-N 3.16Å
167	Y	42.8	Very low	45.5	Very low	101 Å²	101	70 Å²	70	40%	0.396	36%	0.364	S	S	.	.	T	Hydrogen-bonded Turn	trans	-109.4	-8.5	-178.3	-82.6	-96.9	0	0	0	113.4	M163 F164 V217	M163-Y167 HydrophobicContact CG-CD2 4.14Å; M163-Y167 HydrophobicContact CG-CE2 3.88Å; M163-Y167 WeakPolarHBondContact O-CB 3.36Å; M163-Y167 WeakPolarHBondContact O-CD2 3.14Å; F164-Y167 PolarHBondContact O-N 3.47Å; Y167-V217 HydrophobicContact CD1-CG1 4.21Å; Y167-V217 HydrophobicContact CE1-CG1 4.41Å
168	T	49.4	Very low	46.6	Very low	17 Å²	17	69 Å²	69	10%	0.104	35%	0.346	C	S	.	.			trans	-133.5	34.6	-162.4	68.4	0	0	0	0	114.5	F164 D170 E171	F164-T168 HydrophobicContact CD1-CG2 4.28Å; F164-T168 HydrophobicContact CE1-CG2 4.33Å; F164-T168 WeakPolarHBondContact O-CB 3.46Å; F164-T168 VanDerWaalsContact O-CG2 3.26Å; F164-T168 WeakPolarHBondContact O-CG2 3.37Å; F164-T168 PolarHBondContact O-N 3.37Å; F164-T168 PolarHBondContact O-OG1 2.93Å; T168-D170 PolarHBondContact O-N 3.19Å; T168-E171 VanDerWaalsContact CB-CD 3.41Å; T168-E171 WeakPolarHBondContact CB-OE2 3.36Å; T168-E171 HydrophobicContact CG2-CG 3.73Å; T168-E171 WeakPolarHBondContact CG2-OE1 3.43Å; T168-E171 WeakPolarHBondContact CG2-OE2 3.32Å
169	T	44.5	Very low	47.9	Very low	33 Å²	33	68.7 Å²	68.7	20%	0.202	34%	0.344	C	S	.	.	S	Bend	trans	-67.3	-19.8	173	3.5	0	0	0	0	112.5	F114	F114-T169 HydrophobicContact CE1-CG2 4.36Å; F114-T169 WeakPolarHBondContact CE2-O 3.38Å; F114-T169 HydrophobicContact CZ-CG2 4.49Å; F114-T169 WeakPolarHBondContact CZ-O 3.41Å
170	D	51.8	Low	49.2	Very low	11 Å²	11	64.7 Å²	64.7	6%	0.059	31%	0.314	C	S	.	.	S	Bend	trans	-104.6	-11.6	179.7	64.9	-19.7	0	0	0	114	T168 V173 W174 Y214	T168-D170 PolarHBondContact O-N 3.19Å; D170-V173 WeakPolarHBondContact O-CB 3.44Å; D170-V173 PolarHBondContact O-N 3.36Å; D170-W174 PolarHBondContact O-N 3.34Å; D170-W174 PolarHBondContact OD2-NE1 3.33Å; D170-Y214 PolarHBondContact OD1-OH 2.85Å; D170-Y214 PolarHBondContact OD2-OH 3.46Å
171	E	50.7	Low	50.4	Low	39 Å²	39	62.3 Å²	62.3	18%	0.182	29%	0.294	C	S	.	.	H	α-helix	trans	-56.8	-44.1	-176.2	-81.3	-167.3	174.5	0	0	114.3	T168 V173 W174 N175 Y214	T168-E171 VanDerWaalsContact CB-CD 3.41Å; T168-E171 WeakPolarHBondContact CB-OE2 3.36Å; T168-E171 HydrophobicContact CG2-CG 3.73Å; T168-E171 WeakPolarHBondContact CG2-OE1 3.43Å; T168-E171 WeakPolarHBondContact CG2-OE2 3.32Å; E171-V173 VanDerWaalsContact C-N 3.26Å; E171-V173 PolarHBondContact O-N 2.91Å; E171-W174 PolarHBondContact O-N 3.09Å; E171-N175 WeakPolarHBondContact O-CB 3.26Å; E171-N175 VanDerWaalsContact O-CG 3.25Å; E171-N175 PolarHBondContact O-N 3.18Å; E171-N175 PolarHBondContact O-ND2 2.79Å; E171-N175 VanDerWaalsContact O-ND2 3.16Å; E171-Y214 HydrophobicContact CG-CE1 3.7Å; E171-Y214 HydrophobicContact CG-CE2 4.47Å; E171-Y214 WeakPolarHBondContact CG-OH 3.3Å
172	P	52.1	Low	51.5	Low	49 Å²	49	56.7 Å²	56.7	32%	0.318	28%	0.284	S	S	.	.	H	α-helix	trans	-61	-37.7	176.6	-25.1	36.6	0	0	0	112.2	F114 N175 M176	F114-P172 HydrophobicContact CE2-CG 4.26Å; F114-P172 HydrophobicContact CZ-CG 3.73Å; P172-N175 PolarHBondContact O-N 2.76Å; P172-M176 WeakPolarHBondContact O-CB 3.42Å; P172-M176 VanDerWaalsContact O-CG 3.24Å; P172-M176 WeakPolarHBondContact O-CG 3.38Å; P172-M176 PolarHBondContact O-N 3.25Å
173	V	58	Low	53	Low	4 Å²	4	52.7 Å²	52.7	2%	0.024	27%	0.274	C	S	.	.	H	α-helix	trans	-65	-46.7	178.2	178.9	0	0	0	0	110	I71 F106 V107 D170 E171 M176 I177	I71-V173 HydrophobicContact CD1-CG1 4.46Å; F106-V173 HydrophobicContact CB-CG1 4.35Å; V107-V173 HydrophobicContact CG2-CG1 3.81Å; D170-V173 WeakPolarHBondContact O-CB 3.44Å; D170-V173 PolarHBondContact O-N 3.36Å; E171-V173 VanDerWaalsContact C-N 3.26Å; E171-V173 PolarHBondContact O-N 2.91Å; V173-M176 WeakPolarHBondContact O-CB 3.44Å; V173-M176 PolarHBondContact O-N 3.03Å; V173-I177 HydrophobicContact CG1-CD1 4.08Å; V173-I177 WeakPolarHBondContact O-CG1 3.42Å; V173-I177 PolarHBondContact O-N 3.27Å
174	W	62.4	Low	54.3	Low	18 Å²	18	50.4 Å²	50.4	7%	0.068	26%	0.263	C	S	.	.	H	α-helix	trans	-64.8	-41.1	177.1	-67.5	116	0	0	0	112.3	D170 E171 M176 I177 Y178 I206 P210 Y214 I533 I537	D170-W174 PolarHBondContact O-N 3.34Å; D170-W174 PolarHBondContact OD2-NE1 3.33Å; E171-W174 PolarHBondContact O-N 3.09Å; W174-M176 VanDerWaalsContact C-N 3.31Å; W174-M176 PolarHBondContact O-N 2.87Å; W174-I177 HydrophobicContact CE3-CD1 3.79Å; W174-I177 HydrophobicContact CZ3-CD1 3.97Å; W174-I177 CarbonylContact O-C 3.29Å; W174-I177 PolarHBondContact O-N 3.47Å; W174-I177 VanDerWaalsContact O-N 3.11Å; W174-Y178 VanDerWaalsContact C-CD2 3.46Å; W174-Y178 HydrophobicContact CB-CD2 4.46Å; W174-Y178 HydrophobicContact CB-CE2 3.91Å; W174-Y178 WeakPolarHBondContact O-CD2 3.13Å; W174-Y178 PolarHBondContact O-N 3.15Å; W174-I206 HydrophobicContact CZ3-CG2 4Å; W174-P210 HydrophobicContact CD2-CB 3.92Å; W174-P210 HydrophobicContact CD2-CG 3.79Å; W174-P210 HydrophobicContact CE3-CB 4.28Å; W174-P210 HydrophobicContact CE3-CG 3.62Å; W174-P210 HydrophobicContact CG-CB 4.19Å; W174-P210 HydrophobicContact CG-CG 4.41Å; W174-P210 HydrophobicContact CH2-CG 4.18Å; W174-P210 HydrophobicContact CZ2-CB 4.42Å; W174-P210 HydrophobicContact CZ2-CG 4.33Å; W174-P210 HydrophobicContact CZ3-CG 3.83Å; W174-Y214 HydrophobicContact CG-CE2 4.46Å; W174-I533 HydrophobicContact CH2-CG2 3.85Å; W174-I533 HydrophobicContact CZ2-CG2 4.17Å; W174-I537 HydrophobicContact CZ2-CD1 4.22Å
175	N	57.1	Low	55.6	Low	95 Å²	95	45.8 Å²	45.8	51%	0.508	24%	0.244	S	C	.	.	H	α-helix	trans	-57.6	-42.2	173.1	-74.6	-30.9	0	0	0	112.8	E171 P172 Y178 L179	E171-N175 WeakPolarHBondContact O-CB 3.26Å; E171-N175 VanDerWaalsContact O-CG 3.25Å; E171-N175 PolarHBondContact O-N 3.18Å; E171-N175 PolarHBondContact O-ND2 2.79Å; E171-N175 VanDerWaalsContact O-ND2 3.16Å; P172-N175 PolarHBondContact O-N 2.76Å; N175-Y178 PolarHBondContact O-N 3.49Å; N175-L179 WeakPolarHBondContact O-CB 3.39Å; N175-L179 PolarHBondContact O-N 3.07Å
176	M	61.2	Low	56.8	Low	59 Å²	59	44 Å²	44	29%	0.291	23%	0.234	S	C	.	.	H	α-helix	trans	-65.1	-41.2	173.3	-72.3	-179.8	-176.8	0	0	112.5	F106 A109 P172 V173 W174 L179 L180	F106-M176 HydrophobicContact CB-CB 4.14Å; F106-M176 HydrophobicContact CB-SD 4.41Å; F106-M176 HydrophobicContact CD1-CB 3.31Å; F106-M176 HydrophobicContact CD1-CG 3.87Å; F106-M176 HydrophobicContact CD1-SD 3.53Å; F106-M176 VanDerWaalsContact CD1-SD 3.53Å; F106-M176 HydrophobicContact CD2-CB 4.29Å; F106-M176 HydrophobicContact CE1-CB 3.59Å; F106-M176 HydrophobicContact CE1-CG 4.14Å; F106-M176 HydrophobicContact CE1-SD 4.19Å; F106-M176 HydrophobicContact CE2-CB 4.49Å; F106-M176 HydrophobicContact CG-CB 3.67Å; F106-M176 HydrophobicContact CG-SD 4.35Å; F106-M176 HydrophobicContact CZ-CB 4.18Å; A109-M176 HydrophobicContact CB-SD 4.19Å; P172-M176 WeakPolarHBondContact O-CB 3.42Å; P172-M176 VanDerWaalsContact O-CG 3.24Å; P172-M176 WeakPolarHBondContact O-CG 3.38Å; P172-M176 PolarHBondContact O-N 3.25Å; V173-M176 WeakPolarHBondContact O-CB 3.44Å; V173-M176 PolarHBondContact O-N 3.03Å; W174-M176 VanDerWaalsContact C-N 3.31Å; W174-M176 PolarHBondContact O-N 2.87Å; M176-L179 PolarHBondContact O-N 3.29Å; M176-L180 PolarHBondContact O-N 3.34Å
177	I	62.3	Low	58.1	Low	4 Å²	4	45 Å²	45	2%	0.021	24%	0.236	C	C	.	.	H	α-helix	trans	-64	-41.2	174.9	-65.5	167.4	0	0	0	111	I103 F106 V173 W174 L180 T181 T207	I103-I177 HydrophobicContact CG2-CD1 4.49Å; F106-I177 HydrophobicContact CB-CG1 4.36Å; F106-I177 HydrophobicContact CD2-CG1 3.96Å; V173-I177 HydrophobicContact CG1-CD1 4.08Å; V173-I177 WeakPolarHBondContact O-CG1 3.42Å; V173-I177 PolarHBondContact O-N 3.27Å; W174-I177 HydrophobicContact CE3-CD1 3.79Å; W174-I177 HydrophobicContact CZ3-CD1 3.97Å; W174-I177 CarbonylContact O-C 3.29Å; W174-I177 PolarHBondContact O-N 3.47Å; W174-I177 VanDerWaalsContact O-N 3.11Å; I177-L180 PolarHBondContact O-N 2.96Å; I177-T181 VanDerWaalsContact O-CB 3.31Å; I177-T181 WeakPolarHBondContact O-CB 3.44Å; I177-T181 PolarHBondContact O-N 3.47Å; I177-T181 PolarHBondContact O-OG1 3.12Å; I177-T207 HydrophobicContact CG2-CG2 3.62Å
178	Y	61.5	Low	59	Low	27 Å²	27	40.5 Å²	40.5	11%	0.106	22%	0.22	C	C	.	.	H	α-helix	trans	-60.2	-47.8	174.4	-69.3	-63.4	0	0	0	110.9	W174 N175 L180 T181 G182 T207 M211 H241	W174-Y178 VanDerWaalsContact C-CD2 3.46Å; W174-Y178 HydrophobicContact CB-CD2 4.46Å; W174-Y178 HydrophobicContact CB-CE2 3.91Å; W174-Y178 WeakPolarHBondContact O-CD2 3.13Å; W174-Y178 PolarHBondContact O-N 3.15Å; N175-Y178 PolarHBondContact O-N 3.49Å; Y178-L180 PolarHBondContact O-N 3.31Å; Y178-T181 WeakPolarHBondContact O-CB 3.46Å; Y178-T181 PolarHBondContact O-N 3.41Å; Y178-G182 PolarHBondContact O-N 3.07Å; Y178-T207 HydrophobicContact CD1-CG2 3.75Å; Y178-T207 HydrophobicContact CE1-CG2 3.92Å; Y178-T207 HydrophobicContact CG-CG2 4.5Å; Y178-T207 PolarHBondContact OH-O 2.91Å; Y178-M211 HydrophobicContact CD1-CE 4.48Å; Y178-M211 HydrophobicContact CE1-CE 3.71Å; Y178-M211 HydrophobicContact CE1-CG 3.48Å; Y178-M211 VanDerWaalsContact CE1-CG 3.48Å; Y178-M211 HydrophobicContact CE1-SD 3.82Å; Y178-M211 WeakPolarHBondContact OH-CG 3.35Å; Y178-M211 PolarHBondContact OH-N 2.89Å; Y178-H241 AromaticContact CD1-CE1 3.58Å; Y178-H241 AromaticContact CD1-NE2 3.9Å; Y178-H241 AromaticContact CG-CE1 3.83Å
179	L	61.2	Low	59.5	Low	118 Å²	118	43.7 Å²	43.7	62%	0.618	25%	0.248	S	C	*	.	H	α-helix	trans	-59.6	-49	178.9	178.8	63.8	0	0	0	111.2	N175 M176 T181 G182 L183	N175-L179 WeakPolarHBondContact O-CB 3.39Å; N175-L179 PolarHBondContact O-N 3.07Å; M176-L179 PolarHBondContact O-N 3.29Å; L179-T181 VanDerWaalsContact C-N 3.31Å; L179-T181 PolarHBondContact O-N 2.92Å; L179-G182 WeakPolarHBondContact O-CA 3.48Å; L179-G182 PolarHBondContact O-N 3.2Å; L179-G182 VanDerWaalsContact O-N 3.14Å; L179-L183 HydrophobicContact CG-CD1 4.43Å; L179-L183 WeakPolarHBondContact O-CG 3.29Å; L179-L183 PolarHBondContact O-N 3.34Å
180	L	64.1	Low	60.4	Low	21 Å²	21	51.4 Å²	51.4	11%	0.11	27%	0.274	C	S	.	.	H	α-helix	trans	-58.9	-44.8	176.1	175.3	71.8	0	0	0	111.6	L102 F106 M176 I177 Y178 G182 L183 L184 L203	L102-L180 HydrophobicContact CB-CD2 3.56Å; L102-L180 HydrophobicContact CD1-CD1 4.43Å; L102-L180 HydrophobicContact CD1-CD2 3.72Å; L102-L180 HydrophobicContact CD2-CD1 4.15Å; L102-L180 HydrophobicContact CD2-CD2 3.94Å; L102-L180 HydrophobicContact CG-CD2 3.91Å; F106-L180 HydrophobicContact CD2-CD2 4.31Å; F106-L180 HydrophobicContact CE2-CB 3.44Å; F106-L180 VanDerWaalsContact CE2-CB 3.44Å; F106-L180 HydrophobicContact CE2-CD1 4.45Å; F106-L180 HydrophobicContact CE2-CD2 3.46Å; F106-L180 VanDerWaalsContact CE2-CD2 3.46Å; F106-L180 HydrophobicContact CE2-CG 3.92Å; F106-L180 HydrophobicContact CZ-CB 3.7Å; F106-L180 HydrophobicContact CZ-CD2 4.29Å; F106-L180 HydrophobicContact CZ-CG 4.36Å; M176-L180 PolarHBondContact O-N 3.34Å; I177-L180 PolarHBondContact O-N 2.96Å; Y178-L180 PolarHBondContact O-N 3.31Å; L180-G182 PolarHBondContact O-N 2.99Å; L180-L183 CarbonylContact O-C 3.58Å; L180-L183 PolarHBondContact O-N 3.38Å; L180-L183 VanDerWaalsContact O-N 3.09Å; L180-L184 HydrophobicContact CD1-CD1 4.14Å; L180-L184 HydrophobicContact CD1-CG 4.02Å; L180-L184 HydrophobicContact CD2-CD1 4.09Å; L180-L184 HydrophobicContact CG-CD1 3.8Å; L180-L184 HydrophobicContact CG-CG 4.09Å; L180-L184 WeakPolarHBondContact O-CB 3.27Å; L180-L184 WeakPolarHBondContact O-CG 3.15Å; L180-L184 PolarHBondContact O-N 3.41Å; L180-L203 HydrophobicContact CD2-CD1 3.96Å
181	T	63.7	Low	61	Low	3 Å²	3	54.1 Å²	54.1	2%	0.018	29%	0.291	C	S	.	.	H	α-helix	trans	-59.4	-41.1	178.2	-58.1	0	0	0	0	110.4	I177 Y178 L179 L184 T185 L203 L204	I177-T181 VanDerWaalsContact O-CB 3.31Å; I177-T181 WeakPolarHBondContact O-CB 3.44Å; I177-T181 PolarHBondContact O-N 3.47Å; I177-T181 PolarHBondContact O-OG1 3.12Å; Y178-T181 WeakPolarHBondContact O-CB 3.46Å; Y178-T181 PolarHBondContact O-N 3.41Å; L179-T181 VanDerWaalsContact C-N 3.31Å; L179-T181 PolarHBondContact O-N 2.92Å; T181-L184 PolarHBondContact O-N 2.88Å; T181-T185 HydrophobicContact CG2-CG2 4.27Å; T181-T185 VanDerWaalsContact O-CB 3.32Å; T181-T185 WeakPolarHBondContact O-CB 3.41Å; T181-T185 WeakPolarHBondContact O-CG2 3.17Å; T181-T185 PolarHBondContact O-N 2.83Å; T181-T185 PolarHBondContact O-OG1 3.17Å; T181-L203 HydrophobicContact CG2-CB 4.4Å; T181-L204 VanDerWaalsContact CG2-CA 3.49Å; T181-L204 HydrophobicContact CG2-CB 3.48Å; T181-L204 VanDerWaalsContact CG2-CB 3.48Å; T181-L204 HydrophobicContact CG2-CD1 3.53Å; T181-L204 HydrophobicContact CG2-CG 4.06Å
182	G	59.7	Low	61.4	Low	36 Å²	36	55.4 Å²	55.4	37%	0.371	31%	0.308	S	S	.	.	H	α-helix	trans	-59.4	-45.4	171.3	0	0	0	0	0	113.2	Y178 L179 L180 T185 M186	Y178-G182 PolarHBondContact O-N 3.07Å; L179-G182 WeakPolarHBondContact O-CA 3.48Å; L179-G182 PolarHBondContact O-N 3.2Å; L179-G182 VanDerWaalsContact O-N 3.14Å; L180-G182 PolarHBondContact O-N 2.99Å; G182-T185 WeakPolarHBondContact CA-OG1 3.25Å; G182-T185 PolarHBondContact O-OG1 3.03Å; G182-M186 VanDerWaalsContact O-CB 3.3Å; G182-M186 WeakPolarHBondContact O-CB 3.11Å; G182-M186 PolarHBondContact O-N 2.88Å
183	L	65.4	Low	61.7	Low	88 Å²	88	54.7 Å²	54.7	46%	0.461	30%	0.304	S	S	.	.	H	α-helix	trans	-65.6	-43.6	177.4	-67.8	176.2	0	0	0	112.4	L179 L180 M186 H187	L179-L183 HydrophobicContact CG-CD1 4.43Å; L179-L183 WeakPolarHBondContact O-CG 3.29Å; L179-L183 PolarHBondContact O-N 3.34Å; L180-L183 CarbonylContact O-C 3.58Å; L180-L183 PolarHBondContact O-N 3.38Å; L180-L183 VanDerWaalsContact O-N 3.09Å; L183-M186 HydrophobicContact CD2-CE 3.72Å; L183-M186 PolarHBondContact O-N 3.49Å; L183-H187 VanDerWaalsContact O-CB 3.23Å; L183-H187 WeakPolarHBondContact O-CB 3.22Å; L183-H187 PolarHBondContact O-N 2.8Å
184	L	64.2	Low	61.7	Low	26 Å²	26	56.9 Å²	56.9	14%	0.136	31%	0.312	C	S	.	.	H	α-helix	trans	-66.3	-43.5	177.4	-69.6	174	0	0	0	111.1	L102 L180 T181 H187 A188 V196 L203	L102-L184 HydrophobicContact CD1-CD1 4.17Å; L180-L184 HydrophobicContact CD1-CD1 4.14Å; L180-L184 HydrophobicContact CD1-CG 4.02Å; L180-L184 HydrophobicContact CD2-CD1 4.09Å; L180-L184 HydrophobicContact CG-CD1 3.8Å; L180-L184 HydrophobicContact CG-CG 4.09Å; L180-L184 WeakPolarHBondContact O-CB 3.27Å; L180-L184 WeakPolarHBondContact O-CG 3.15Å; L180-L184 PolarHBondContact O-N 3.41Å; T181-L184 PolarHBondContact O-N 2.88Å; L184-H187 PolarHBondContact O-N 3.46Å; L184-A188 VanDerWaalsContact O-CB 3.28Å; L184-A188 WeakPolarHBondContact O-CB 3Å; L184-A188 PolarHBondContact O-N 3.02Å; L184-V196 HydrophobicContact CB-CG1 4.06Å; L184-V196 HydrophobicContact CD2-CG1 3.84Å; L184-V196 WeakPolarHBondContact O-CG1 3.47Å; L184-L203 HydrophobicContact CD1-CD1 3.36Å
185	T	61.9	Low	61.5	Low	23 Å²	23	58 Å²	58	14%	0.141	32%	0.321	C	S	.	.	H	α-helix	trans	-64.4	-41.8	177.4	52.9	0	0	0	0	111.6	T181 G182 A188 A189 L204 V248 L252	T181-T185 HydrophobicContact CG2-CG2 4.27Å; T181-T185 VanDerWaalsContact O-CB 3.32Å; T181-T185 WeakPolarHBondContact O-CB 3.41Å; T181-T185 WeakPolarHBondContact O-CG2 3.17Å; T181-T185 PolarHBondContact O-N 2.83Å; T181-T185 PolarHBondContact O-OG1 3.17Å; G182-T185 WeakPolarHBondContact CA-OG1 3.25Å; G182-T185 PolarHBondContact O-OG1 3.03Å; T185-A188 PolarHBondContact O-N 2.87Å; T185-A189 WeakPolarHBondContact O-CB 3.36Å; T185-A189 PolarHBondContact O-N 3.47Å; T185-L204 HydrophobicContact CG2-CD2 4.3Å; T185-V248 HydrophobicContact CG2-CG1 3.56Å; T185-L252 HydrophobicContact CG2-CD2 4.13Å
186	M	62.3	Low	61.7	Low	81 Å²	81	54.5 Å²	54.5	40%	0.399	30%	0.303	S	S	.	.	H	α-helix	trans	-62.9	-43.2	172.4	178.7	178.3	52.2	0	0	111.8	G182 L183 A189 R190	G182-M186 VanDerWaalsContact O-CB 3.3Å; G182-M186 WeakPolarHBondContact O-CB 3.11Å; G182-M186 PolarHBondContact O-N 2.88Å; L183-M186 HydrophobicContact CD2-CE 3.72Å; L183-M186 PolarHBondContact O-N 3.49Å; M186-A189 PolarHBondContact O-N 2.97Å; M186-R190 WeakPolarHBondContact O-CG 3.41Å; M186-R190 PolarHBondContact O-N 3.28Å
187	H	63.4	Low	61.6	Low	91 Å²	91	51.9 Å²	51.9	42%	0.421	29%	0.29	S	S	.	.	H	α-helix	trans	-66.2	-43.6	178.4	-174.3	95.6	0	0	0	111.3	L183 L184 A189 R190 T191 V196	L183-H187 VanDerWaalsContact O-CB 3.23Å; L183-H187 WeakPolarHBondContact O-CB 3.22Å; L183-H187 PolarHBondContact O-N 2.8Å; L184-H187 PolarHBondContact O-N 3.46Å; H187-A189 VanDerWaalsContact C-N 3.27Å; H187-A189 PolarHBondContact O-N 2.98Å; H187-R190 PolarHBondContact O-N 3.44Å; H187-R190 VanDerWaalsContact O-N 3.1Å; H187-T191 PolarHBondContact CD2-OG1 3.07Å; H187-T191 VanDerWaalsContact NE2-CG2 3.34Å; H187-T191 WeakPolarHBondContact NE2-CG2 3.22Å; H187-T191 PolarHBondContact NE2-OG1 2.84Å; H187-T191 PolarHBondContact O-N 3.46Å; H187-T191 PolarHBondContact O-OG1 3.34Å; H187-V196 HydrophobicContact CB-CG1 4.11Å
188	A	61.4	Low	61.5	Low	7 Å²	7	54 Å²	54	6%	0.058	30%	0.3	C	S	.	.	H	α-helix	trans	-58.1	-39.9	173.8	0	0	0	0	0	111.8	L184 T185 A192 V196 A197 L252	L184-A188 VanDerWaalsContact O-CB 3.28Å; L184-A188 WeakPolarHBondContact O-CB 3Å; L184-A188 PolarHBondContact O-N 3.02Å; T185-A188 PolarHBondContact O-N 2.87Å; A188-A192 VanDerWaalsContact O-CA 3.28Å; A188-A192 WeakPolarHBondContact O-CA 3.47Å; A188-A192 PolarHBondContact O-N 2.94Å; A188-V196 HydrophobicContact CB-CB 4.22Å; A188-V196 HydrophobicContact CB-CG1 3.98Å; A188-A197 HydrophobicContact CB-CB 4.02Å; A188-L252 HydrophobicContact CB-CD1 3.87Å
189	A	59.7	Low	61.5	Low	85 Å²	85	52.9 Å²	52.9	70%	0.702	30%	0.295	S	S	*	.	H	α-helix	trans	-67.2	-36	175.8	0	0	0	0	0	112.7	T185 M186 H187	T185-A189 WeakPolarHBondContact O-CB 3.36Å; T185-A189 PolarHBondContact O-N 3.47Å; M186-A189 PolarHBondContact O-N 2.97Å; H187-A189 VanDerWaalsContact C-N 3.27Å; H187-A189 PolarHBondContact O-N 2.98Å
190	R	64.3	Low	61.6	Low	194 Å²	194	47.2 Å²	47.2	73%	0.732	27%	0.266	S	S	*	.	H	α-helix	trans	-77.2	-45	180	-77.5	-176.6	173.2	155.5	0.9	113.6	M186 H187	M186-R190 WeakPolarHBondContact O-CG 3.41Å; M186-R190 PolarHBondContact O-N 3.28Å; H187-R190 PolarHBondContact O-N 3.44Å; H187-R190 VanDerWaalsContact O-N 3.1Å
191	T	63.5	Low	61.6	Low	69 Å²	69	46.9 Å²	46.9	42%	0.423	26%	0.264	S	S	.	.	H	α-helix	trans	-93.9	-9.3	-173.4	58.7	0	0	0	0	113.4	H187 S193	H187-T191 PolarHBondContact CD2-OG1 3.07Å; H187-T191 VanDerWaalsContact NE2-CG2 3.34Å; H187-T191 WeakPolarHBondContact NE2-CG2 3.22Å; H187-T191 PolarHBondContact NE2-OG1 2.84Å; H187-T191 PolarHBondContact O-N 3.46Å; H187-T191 PolarHBondContact O-OG1 3.34Å; T191-S193 PolarHBondContact O-N 3.24Å; T191-S193 WeakPolarHBondContact OG1-CB 3.24Å; T191-S193 PolarHBondContact OG1-N 3.44Å
192	A	60.8	Low	61.6	Low	66 Å²	66	49.1 Å²	49.1	55%	0.545	28%	0.279	S	S	.	.			trans	52	21.5	-166.7	0	0	0	0	0	113	A188 R194	A188-A192 VanDerWaalsContact O-CA 3.28Å; A188-A192 WeakPolarHBondContact O-CA 3.47Å; A188-A192 PolarHBondContact O-N 2.94Å; A192-R194 PolarHBondContact O-N 3.13Å; A192-R194 VanDerWaalsContact O-N 3.14Å
193	S	57.4	Low	61.8	Low	33 Å²	33	47.4 Å²	47.4	23%	0.231	26%	0.261	C	S	.	.			trans	-67.8	114.4	-176.8	177	0	0	0	0	110.3	T191 V195 V196 A197	T191-S193 PolarHBondContact O-N 3.24Å; T191-S193 WeakPolarHBondContact OG1-CB 3.24Å; T191-S193 PolarHBondContact OG1-N 3.44Å; S193-V195 PolarHBondContact O-N 2.87Å; S193-V196 PolarHBondContact O-N 3.02Å; S193-V196 PolarHBondContact OG-N 3.42Å; S193-A197 PolarHBondContact O-N 2.85Å
194	R	59	Low	61.8	Low	50 Å²	50	43.7 Å²	43.7	19%	0.189	24%	0.242	C	C	.	.	H	α-helix	trans	-53.8	-43.9	174.3	-67.5	-179.3	-175.6	159.9	7.4	110.4	A192 V196 A197 F198 L259 D590	A192-R194 PolarHBondContact O-N 3.13Å; A192-R194 VanDerWaalsContact O-N 3.14Å; R194-V196 PolarHBondContact O-N 3.49Å; R194-A197 PolarHBondContact O-N 3.33Å; R194-F198 HydrophobicContact CB-CD2 4.35Å; R194-F198 WeakPolarHBondContact O-CB 3.35Å; R194-F198 WeakPolarHBondContact O-CD2 3.5Å; R194-F198 PolarHBondContact O-N 3.39Å; R194-L259 HydrophobicContact CG-CB 4.2Å; R194-L259 HydrophobicContact CG-CD1 4.07Å; R194-L259 HydrophobicContact CG-CD2 4.5Å; R194-L259 HydrophobicContact CG-CG 4.5Å; R194-D590 IonicContact CZ-OD1 3.43Å; R194-D590 IonicContact CZ-OD2 3.71Å; R194-D590 IonicContact NH1-OD1 3.99Å; R194-D590 PolarHBondContact NH1-OD1 2.89Å; R194-D590 IonicContact NH1-OD2 3.39Å; R194-D590 PolarHBondContact NH1-OD2 3.09Å; R194-D590 IonicContact NH2-OD1 2.72Å; R194-D590 PolarHBondContact NH2-OD1 3.35Å; R194-D590 IonicContact NH2-OD2 3.7Å
195	V	57	Low	61.9	Low	42 Å²	42	45 Å²	45	26%	0.255	25%	0.248	S	C	.	.	H	α-helix	trans	-53.4	-53.9	178.5	175.3	0	0	0	0	111.3	Y95 S193 A197 F198 C199	Y95-V195 HydrophobicContact CD1-CB 4.31Å; Y95-V195 HydrophobicContact CD1-CG1 3.72Å; Y95-V195 VanDerWaalsContact CE1-CA 3.46Å; Y95-V195 HydrophobicContact CE1-CB 3.57Å; Y95-V195 HydrophobicContact CE1-CG1 3.38Å; Y95-V195 HydrophobicContact CE1-CG2 3.58Å; S193-V195 PolarHBondContact O-N 2.87Å; V195-A197 VanDerWaalsContact C-N 3.31Å; V195-A197 PolarHBondContact O-N 3.14Å; V195-F198 PolarHBondContact O-N 3.47Å; V195-C199 PolarHBondContact O-N 3.43Å; V195-C199 PolarHBondContact O-SG 2.86Å
196	V	61.6	Low	62.1	Low	21 Å²	21	45.1 Å²	45.1	13%	0.127	25%	0.248	C	C	.	.	H	α-helix	trans	-70.1	-33.8	-175.4	-177.1	0	0	0	0	110.7	L184 H187 A188 S193 R194 C199 G200	L184-V196 HydrophobicContact CB-CG1 4.06Å; L184-V196 HydrophobicContact CD2-CG1 3.84Å; L184-V196 WeakPolarHBondContact O-CG1 3.47Å; H187-V196 HydrophobicContact CB-CG1 4.11Å; A188-V196 HydrophobicContact CB-CB 4.22Å; A188-V196 HydrophobicContact CB-CG1 3.98Å; S193-V196 PolarHBondContact O-N 3.02Å; S193-V196 PolarHBondContact OG-N 3.42Å; R194-V196 PolarHBondContact O-N 3.49Å; V196-C199 PolarHBondContact O-N 3.38Å; V196-G200 PolarHBondContact O-N 2.8Å
197	A	58.3	Low	62.2	Low	4 Å²	4	41.3 Å²	41.3	3%	0.033	23%	0.229	C	C	.	.	H	α-helix	trans	-65.5	-44.4	173.1	0	0	0	0	0	112.3	A188 S193 R194 V195 C199 G200 L201 L252 I256	A188-A197 HydrophobicContact CB-CB 4.02Å; S193-A197 PolarHBondContact O-N 2.85Å; R194-A197 PolarHBondContact O-N 3.33Å; V195-A197 VanDerWaalsContact C-N 3.31Å; V195-A197 PolarHBondContact O-N 3.14Å; A197-C199 VanDerWaalsContact C-N 3.32Å; A197-C199 PolarHBondContact O-N 3.29Å; A197-G200 PolarHBondContact O-N 3.32Å; A197-L201 WeakPolarHBondContact O-CB 3.18Å; A197-L201 PolarHBondContact O-N 2.89Å; A197-L252 HydrophobicContact CB-CD1 3.68Å; A197-L252 HydrophobicContact CB-CG 4.29Å; A197-I256 HydrophobicContact CB-CD1 3.95Å; A197-I256 HydrophobicContact CB-CG1 3.63Å
198	F	61.7	Low	62.4	Low	50 Å²	50	39.4 Å²	39.4	22%	0.219	22%	0.221	C	C	.	.	H	α-helix	trans	-68.6	-26.4	177.1	-86.2	-71	0	0	0	113.4	Y95 R194 V195 P202 I256 A260	Y95-F198 HydrophobicContact CD2-CB 3.99Å; Y95-F198 HydrophobicContact CE2-CB 4.18Å; Y95-F198 HydrophobicContact CE2-CD2 4.39Å; Y95-F198 HydrophobicContact CE2-CG 4.39Å; Y95-F198 HydrophobicContact CG-CB 4.31Å; R194-F198 HydrophobicContact CB-CD2 4.35Å; R194-F198 WeakPolarHBondContact O-CB 3.35Å; R194-F198 WeakPolarHBondContact O-CD2 3.5Å; R194-F198 PolarHBondContact O-N 3.39Å; V195-F198 PolarHBondContact O-N 3.47Å; F198-P202 WeakPolarHBondContact O-CD 3.36Å; F198-P202 WeakPolarHBondContact O-CG 3.21Å; F198-I256 HydrophobicContact CD1-CG2 4.44Å; F198-I256 HydrophobicContact CE1-CG2 3.74Å; F198-I256 HydrophobicContact CE2-CG2 3.97Å; F198-I256 HydrophobicContact CZ-CG2 3.47Å; F198-I256 VanDerWaalsContact CZ-CG2 3.47Å; F198-A260 HydrophobicContact CZ-CB 4.19Å
199	C	61.6	Low	62.7	Low	2 Å²	2	40.2 Å²	40.2	1%	0.014	22%	0.223	C	C	.	.	H	α-helix	trans	-81.2	-41.8	171	-70	0	0	0	0	112.3	C99 V195 V196 A197 L201 P202 L203	C99-C199 VanDerWaalsContact SG-CA 3.52Å; C99-C199 PolarHBondContact SG-O 2.85Å; V195-C199 PolarHBondContact O-N 3.43Å; V195-C199 PolarHBondContact O-SG 2.86Å; V196-C199 PolarHBondContact O-N 3.38Å; A197-C199 VanDerWaalsContact C-N 3.32Å; A197-C199 PolarHBondContact O-N 3.29Å; C199-L201 PolarHBondContact O-N 2.91Å; C199-P202 WeakPolarHBondContact O-CD 3.16Å; C199-L203 WeakPolarHBondContact O-CG 2.97Å; C199-L203 PolarHBondContact O-N 3.31Å
200	G	62.3	Low	62.9	Low	0 Å²	0	36.2 Å²	36.2	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-66.6	-35.6	-178.9	0	0	0	0	0	113.1	V196 A197 L203 L204	V196-G200 PolarHBondContact O-N 2.8Å; A197-G200 PolarHBondContact O-N 3.32Å; G200-L203 PolarHBondContact O-N 3.22Å; G200-L204 WeakPolarHBondContact O-CB 3.5Å; G200-L204 PolarHBondContact O-N 3.45Å
201	L	64.2	Low	63.1	Low	13 Å²	13	27.1 Å²	27.1	7%	0.068	16%	0.156	C	C	.	.	H	α-helix	trans	-65.2	-51.4	-178.6	177.5	70.2	0	0	0	113	A197 C199 L204 I205 V249 L252 I256 Y339	A197-L201 WeakPolarHBondContact O-CB 3.18Å; A197-L201 PolarHBondContact O-N 2.89Å; C199-L201 PolarHBondContact O-N 2.91Å; L201-L204 PolarHBondContact O-N 3.06Å; L201-I205 HydrophobicContact CD1-CD1 4.01Å; L201-I205 HydrophobicContact CD1-CG1 4.35Å; L201-I205 HydrophobicContact CG-CD1 3.93Å; L201-I205 VanDerWaalsContact O-CG1 3.3Å; L201-I205 WeakPolarHBondContact O-CG1 3.37Å; L201-I205 PolarHBondContact O-N 3.35Å; L201-V249 HydrophobicContact CD1-CG1 4.03Å; L201-L252 HydrophobicContact CB-CD2 3.8Å; L201-I256 HydrophobicContact CB-CD1 3.96Å; L201-I256 HydrophobicContact CD2-CD1 3.76Å; L201-I256 HydrophobicContact CG-CD1 4.43Å; L201-Y339 HydrophobicContact CD2-CE1 4.08Å
202	P	63.7	Low	63.3	Low	51 Å²	51	24.5 Å²	24.5	33%	0.331	14%	0.14	S	C	.	.	H	α-helix	trans	-58.1	-45.1	173.2	-25.7	34.4	0	0	0	112.9	F198 C199 L204 I205 I206	F198-P202 WeakPolarHBondContact O-CD 3.36Å; F198-P202 WeakPolarHBondContact O-CG 3.21Å; C199-P202 WeakPolarHBondContact O-CD 3.16Å; P202-L204 VanDerWaalsContact C-N 3.3Å; P202-L204 PolarHBondContact O-N 3.31Å; P202-I205 PolarHBondContact O-N 3.42Å; P202-I206 WeakPolarHBondContact O-CB 3.39Å; P202-I206 WeakPolarHBondContact O-CG1 3.38Å; P202-I206 PolarHBondContact O-N 3.22Å
203	L	64	Low	63.6	Low	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-60.1	-42.1	177.7	-72.2	170.1	0	0	0	111.3	L102 I103 L180 T181 L184 C199 G200 I205 I206 T207	L102-L203 HydrophobicContact CD1-CD1 4.47Å; I103-L203 HydrophobicContact CD1-CD2 3.85Å; I103-L203 HydrophobicContact CG1-CD2 3.75Å; L180-L203 HydrophobicContact CD2-CD1 3.96Å; T181-L203 HydrophobicContact CG2-CB 4.4Å; L184-L203 HydrophobicContact CD1-CD1 3.36Å; C199-L203 WeakPolarHBondContact O-CG 2.97Å; C199-L203 PolarHBondContact O-N 3.31Å; G200-L203 PolarHBondContact O-N 3.22Å; L203-I205 PolarHBondContact O-N 3.18Å; L203-I206 WeakPolarHBondContact O-CB 3.32Å; L203-I206 PolarHBondContact O-N 2.74Å; L203-T207 WeakPolarHBondContact O-CG2 3.16Å; L203-T207 PolarHBondContact O-N 3.22Å; L203-T207 VanDerWaalsContact O-N 3.1Å
204	L	66.3	Low	63.9	Low	9 Å²	9	22.1 Å²	22.1	5%	0.047	11%	0.112	C	C	.	.	H	α-helix	trans	-64.3	-41.1	175.5	-170.2	64.5	0	0	0	112.8	T181 T185 G200 L201 P202 T207 V245 V248 V249	T181-L204 VanDerWaalsContact CG2-CA 3.49Å; T181-L204 HydrophobicContact CG2-CB 3.48Å; T181-L204 VanDerWaalsContact CG2-CB 3.48Å; T181-L204 HydrophobicContact CG2-CD1 3.53Å; T181-L204 HydrophobicContact CG2-CG 4.06Å; T185-L204 HydrophobicContact CG2-CD2 4.3Å; G200-L204 WeakPolarHBondContact O-CB 3.5Å; G200-L204 PolarHBondContact O-N 3.45Å; L201-L204 PolarHBondContact O-N 3.06Å; P202-L204 VanDerWaalsContact C-N 3.3Å; P202-L204 PolarHBondContact O-N 3.31Å; L204-T207 PolarHBondContact O-N 3.09Å; L204-T207 PolarHBondContact O-OG1 2.92Å; L204-V245 HydrophobicContact CD1-CB 4.1Å; L204-V245 HydrophobicContact CD1-CG1 3.64Å; L204-V245 HydrophobicContact CD1-CG2 3.8Å; L204-V245 HydrophobicContact CG-CG1 3.9Å; L204-V248 HydrophobicContact CD2-CB 3.94Å; L204-V248 HydrophobicContact CD2-CG1 3.6Å; L204-V249 HydrophobicContact CB-CG2 4.36Å; L204-V249 HydrophobicContact CD2-CB 4.09Å; L204-V249 HydrophobicContact CD2-CG2 3.29Å; L204-V249 HydrophobicContact CG-CG2 3.54Å
205	I	66	Low	64.5	Low	55 Å²	55	20.2 Å²	20.2	28%	0.282	11%	0.106	S	C	.	.	H	α-helix	trans	-66.4	-43.1	176.5	-68.2	166.5	0	0	0	110.9	L201 P202 L203 T207 I208	L201-I205 HydrophobicContact CD1-CD1 4.01Å; L201-I205 HydrophobicContact CD1-CG1 4.35Å; L201-I205 HydrophobicContact CG-CD1 3.93Å; L201-I205 VanDerWaalsContact O-CG1 3.3Å; L201-I205 WeakPolarHBondContact O-CG1 3.37Å; L201-I205 PolarHBondContact O-N 3.35Å; P202-I205 PolarHBondContact O-N 3.42Å; L203-I205 PolarHBondContact O-N 3.18Å; I205-T207 PolarHBondContact O-N 3.47Å; I205-I208 WeakPolarHBondContact O-CB 3.32Å; I205-I208 PolarHBondContact O-N 2.83Å; I205-I208 VanDerWaalsContact O-N 3.12Å
206	I	64.9	Low	65.1	Low	25 Å²	25	19.2 Å²	19.2	13%	0.128	10%	0.098	C	C	.	.	H	α-helix	trans	-55.6	-39.5	177.1	-75.1	168.7	0	0	0	110.4	I103 W174 P202 L203 I208 P210 I533	I103-I206 HydrophobicContact CD1-CD1 4.26Å; W174-I206 HydrophobicContact CZ3-CG2 4Å; P202-I206 WeakPolarHBondContact O-CB 3.39Å; P202-I206 WeakPolarHBondContact O-CG1 3.38Å; P202-I206 PolarHBondContact O-N 3.22Å; L203-I206 WeakPolarHBondContact O-CB 3.32Å; L203-I206 PolarHBondContact O-N 2.74Å; I206-I208 VanDerWaalsContact C-N 3.3Å; I206-I208 PolarHBondContact O-N 3.39Å; I206-P210 WeakPolarHBondContact O-CD 3.24Å; I206-I533 HydrophobicContact CB-CD1 4.01Å; I206-I533 HydrophobicContact CG1-CD1 4.02Å; I206-I533 HydrophobicContact CG2-CD1 3.64Å; I206-I533 HydrophobicContact CG2-CG1 4.28Å
207	T	65.7	Low	65.2	Low	1 Å²	1	19.5 Å²	19.5	1%	0.006	10%	0.1	C	C	.	.	H	α-helix	trans	-70.6	-18.7	-178.2	68.6	0	0	0	0	114.9	I177 Y178 L203 L204 I205 Y209 P210 M211	I177-T207 HydrophobicContact CG2-CG2 3.62Å; Y178-T207 HydrophobicContact CD1-CG2 3.75Å; Y178-T207 HydrophobicContact CE1-CG2 3.92Å; Y178-T207 HydrophobicContact CG-CG2 4.5Å; Y178-T207 PolarHBondContact OH-O 2.91Å; L203-T207 WeakPolarHBondContact O-CG2 3.16Å; L203-T207 PolarHBondContact O-N 3.22Å; L203-T207 VanDerWaalsContact O-N 3.1Å; L204-T207 PolarHBondContact O-N 3.09Å; L204-T207 PolarHBondContact O-OG1 2.92Å; I205-T207 PolarHBondContact O-N 3.47Å; T207-Y209 VanDerWaalsContact C-N 3.31Å; T207-Y209 PolarHBondContact O-N 3.3Å; T207-P210 VanDerWaalsContact O-CD 3.3Å; T207-P210 WeakPolarHBondContact O-CD 3.46Å; T207-P210 WeakPolarHBondContact O-CG 3.18Å; T207-M211 WeakPolarHBondContact O-CE 3.48Å; T207-M211 WeakPolarHBondContact O-CG 3.35Å; T207-M211 PolarHBondContact O-N 2.79Å
208	I	67.7	Low	65.5	Low	50 Å²	50	20.2 Å²	20.2	26%	0.256	10%	0.103	S	C	.	.	H	α-helix	trans	-64.1	-37.9	178.6	-64.3	171.9	0	0	0	111.4	I205 I206 M211 V212 L242 V245 V249	I205-I208 WeakPolarHBondContact O-CB 3.32Å; I205-I208 PolarHBondContact O-N 2.83Å; I205-I208 VanDerWaalsContact O-N 3.12Å; I206-I208 VanDerWaalsContact C-N 3.3Å; I206-I208 PolarHBondContact O-N 3.39Å; I208-M211 HydrophobicContact CG1-CE 4.26Å; I208-M211 PolarHBondContact O-N 3.42Å; I208-V212 HydrophobicContact CG2-CG2 4.27Å; I208-V212 WeakPolarHBondContact O-CG2 3.44Å; I208-V212 PolarHBondContact O-N 2.81Å; I208-L242 HydrophobicContact CG2-CD2 4.38Å; I208-V245 HydrophobicContact CD1-CG1 4.06Å; I208-V245 HydrophobicContact CG1-CG1 3.65Å; I208-V249 HydrophobicContact CD1-CG2 4.45Å
209	Y	67.4	Low	65.8	Low	24 Å²	24	19.6 Å²	19.6	9%	0.094	10%	0.099	C	C	.	.	H	α-helix	trans	-62.2	-56.2	-178.4	-174.3	-102.9	0	0	0	112.9	T207 M211 V212 Q213 F350 I533 D534 I537	T207-Y209 VanDerWaalsContact C-N 3.31Å; T207-Y209 PolarHBondContact O-N 3.3Å; Y209-M211 VanDerWaalsContact C-N 3.31Å; Y209-M211 PolarHBondContact O-N 3.29Å; Y209-V212 PolarHBondContact O-N 3.39Å; Y209-V212 VanDerWaalsContact O-N 3.12Å; Y209-Q213 HydrophobicContact CD1-CG 4.11Å; Y209-Q213 HydrophobicContact CE1-CG 3.84Å; Y209-Q213 HydrophobicContact CE2-CG 4.5Å; Y209-Q213 VanDerWaalsContact CE2-NE2 3.33Å; Y209-Q213 WeakPolarHBondContact O-CG 3.49Å; Y209-Q213 PolarHBondContact O-N 3.37Å; Y209-Q213 PolarHBondContact OH-NE2 3.11Å; Y209-Q213 VanDerWaalsContact OH-NE2 3.15Å; Y209-F350 HydrophobicContact CE2-CE1 4.27Å; Y209-F350 HydrophobicContact CE2-CZ 4.26Å; Y209-I533 HydrophobicContact CD1-CB 4.42Å; Y209-I533 HydrophobicContact CD1-CG2 3.52Å; Y209-I533 HydrophobicContact CE1-CG2 4.12Å; Y209-I533 HydrophobicContact CG-CG2 4.37Å; Y209-D534 HydrophobicContact CE1-CB 4.36Å; Y209-D534 PolarHBondContact OH-OD1 2.92Å; Y209-I537 HydrophobicContact CD1-CD1 3.89Å; Y209-I537 HydrophobicContact CE1-CD1 3.72Å
210	P	63.5	Low	65.9	Low	2 Å²	2	21.7 Å²	21.7	1%	0.013	11%	0.107	C	C	.	.	H	α-helix	trans	-60.5	-38.3	176.7	21.8	-31	0	0	0	112	W174 I206 T207 V212 Q213 Y214	W174-P210 HydrophobicContact CD2-CB 3.92Å; W174-P210 HydrophobicContact CD2-CG 3.79Å; W174-P210 HydrophobicContact CE3-CB 4.28Å; W174-P210 HydrophobicContact CE3-CG 3.62Å; W174-P210 HydrophobicContact CG-CB 4.19Å; W174-P210 HydrophobicContact CG-CG 4.41Å; W174-P210 HydrophobicContact CH2-CG 4.18Å; W174-P210 HydrophobicContact CZ2-CB 4.42Å; W174-P210 HydrophobicContact CZ2-CG 4.33Å; W174-P210 HydrophobicContact CZ3-CG 3.83Å; I206-P210 WeakPolarHBondContact O-CD 3.24Å; T207-P210 VanDerWaalsContact O-CD 3.3Å; T207-P210 WeakPolarHBondContact O-CD 3.46Å; T207-P210 WeakPolarHBondContact O-CG 3.18Å; P210-V212 VanDerWaalsContact C-N 3.3Å; P210-V212 PolarHBondContact O-N 3.16Å; P210-Q213 CarbonylContact O-C 3.55Å; P210-Q213 PolarHBondContact O-N 3.39Å; P210-Q213 VanDerWaalsContact O-N 3.09Å; P210-Y214 HydrophobicContact CB-CD2 4.15Å; P210-Y214 HydrophobicContact CB-CE2 3.85Å; P210-Y214 WeakPolarHBondContact O-CD2 3.4Å; P210-Y214 PolarHBondContact O-N 3.42Å
211	M	67.9	Low	65.9	Low	3 Å²	3	23 Å²	23	2%	0.015	12%	0.115	C	C	.	.	H	α-helix	trans	-56.2	-44.7	173.4	-74.7	-171.4	-89.1	0	0	112.4	Y178 T207 I208 Y209 Q213 L215 T238 H241 L242 V245	Y178-M211 HydrophobicContact CD1-CE 4.48Å; Y178-M211 HydrophobicContact CE1-CE 3.71Å; Y178-M211 HydrophobicContact CE1-CG 3.48Å; Y178-M211 VanDerWaalsContact CE1-CG 3.48Å; Y178-M211 HydrophobicContact CE1-SD 3.82Å; Y178-M211 WeakPolarHBondContact OH-CG 3.35Å; Y178-M211 PolarHBondContact OH-N 2.89Å; T207-M211 WeakPolarHBondContact O-CE 3.48Å; T207-M211 WeakPolarHBondContact O-CG 3.35Å; T207-M211 PolarHBondContact O-N 2.79Å; I208-M211 HydrophobicContact CG1-CE 4.26Å; I208-M211 PolarHBondContact O-N 3.42Å; Y209-M211 VanDerWaalsContact C-N 3.31Å; Y209-M211 PolarHBondContact O-N 3.29Å; M211-Q213 VanDerWaalsContact C-N 3.35Å; M211-L215 WeakPolarHBondContact O-CB 3.4Å; M211-L215 PolarHBondContact O-N 2.92Å; M211-T238 HydrophobicContact CB-CG2 4.42Å; M211-H241 HydrophobicContact SD-CB 4.12Å; M211-L242 HydrophobicContact CB-CD2 3.67Å; M211-L242 HydrophobicContact CB-CG 4.17Å; M211-L242 HydrophobicContact CE-CD2 4.21Å; M211-L242 HydrophobicContact CG-CD2 4.41Å; M211-L242 HydrophobicContact SD-CD2 3.93Å; M211-L242 HydrophobicContact SD-CG 4.22Å; M211-V245 HydrophobicContact CE-CB 3.84Å; M211-V245 HydrophobicContact CE-CG1 3.76Å; M211-V245 HydrophobicContact CE-CG2 3.4Å; M211-V245 VanDerWaalsContact CE-CG2 3.4Å; M211-V245 HydrophobicContact SD-CG2 4.07Å
212	V	69.2	Low	65.9	Low	13 Å²	13	22.9 Å²	22.9	8%	0.079	12%	0.116	C	C	.	.	H	α-helix	trans	-65.7	-39.1	177	167.6	0	0	0	0	111.1	I208 Y209 P210 W216 L242 F318 Y319	I208-V212 HydrophobicContact CG2-CG2 4.27Å; I208-V212 WeakPolarHBondContact O-CG2 3.44Å; I208-V212 PolarHBondContact O-N 2.81Å; Y209-V212 PolarHBondContact O-N 3.39Å; Y209-V212 VanDerWaalsContact O-N 3.12Å; P210-V212 VanDerWaalsContact C-N 3.3Å; P210-V212 PolarHBondContact O-N 3.16Å; V212-W216 VanDerWaalsContact O-CB 3.3Å; V212-W216 WeakPolarHBondContact O-CB 3.38Å; V212-W216 PolarHBondContact O-N 3.49Å; V212-L242 HydrophobicContact CG2-CD2 4.27Å; V212-F318 HydrophobicContact CG1-CB 3.69Å; V212-Y319 HydrophobicContact CG1-CD1 4.33Å; V212-Y319 HydrophobicContact CG1-CE1 3.96Å
213	Q	66.6	Low	66	Low	17 Å²	17	21.9 Å²	21.9	8%	0.079	11%	0.108	C	C	.	.	H	α-helix	trans	-64.6	-47.9	175.8	-65.6	-57.9	-30.9	0	0	112	Y209 P210 M211 W216 V217 Y319	Y209-Q213 HydrophobicContact CD1-CG 4.11Å; Y209-Q213 HydrophobicContact CE1-CG 3.84Å; Y209-Q213 HydrophobicContact CE2-CG 4.5Å; Y209-Q213 VanDerWaalsContact CE2-NE2 3.33Å; Y209-Q213 WeakPolarHBondContact O-CG 3.49Å; Y209-Q213 PolarHBondContact O-N 3.37Å; Y209-Q213 PolarHBondContact OH-NE2 3.11Å; Y209-Q213 VanDerWaalsContact OH-NE2 3.15Å; P210-Q213 CarbonylContact O-C 3.55Å; P210-Q213 PolarHBondContact O-N 3.39Å; P210-Q213 VanDerWaalsContact O-N 3.09Å; M211-Q213 VanDerWaalsContact C-N 3.35Å; Q213-W216 WeakPolarHBondContact O-CB 3.05Å; Q213-W216 PolarHBondContact O-N 3.42Å; Q213-V217 WeakPolarHBondContact O-CG2 3.13Å; Q213-V217 PolarHBondContact O-N 2.86Å; Q213-Y319 PolarHBondContact NE2-OH 2.96Å; Q213-Y319 VanDerWaalsContact NE2-OH 3.11Å
214	Y	64.1	Low	65.7	Low	32 Å²	32	25.9 Å²	25.9	13%	0.125	13%	0.132	C	C	.	.	H	α-helix	trans	-66	-42.5	179.1	-68.9	-59.7	0	0	0	111.6	D170 E171 W174 P210 W216 V217 D218	D170-Y214 PolarHBondContact OD1-OH 2.85Å; D170-Y214 PolarHBondContact OD2-OH 3.46Å; E171-Y214 HydrophobicContact CG-CE1 3.7Å; E171-Y214 HydrophobicContact CG-CE2 4.47Å; E171-Y214 WeakPolarHBondContact CG-OH 3.3Å; W174-Y214 HydrophobicContact CG-CE2 4.46Å; P210-Y214 HydrophobicContact CB-CD2 4.15Å; P210-Y214 HydrophobicContact CB-CE2 3.85Å; P210-Y214 WeakPolarHBondContact O-CD2 3.4Å; P210-Y214 PolarHBondContact O-N 3.42Å; Y214-W216 PolarHBondContact O-N 2.92Å; Y214-V217 PolarHBondContact O-N 3.41Å; Y214-V217 VanDerWaalsContact O-N 3.1Å; Y214-D218 WeakPolarHBondContact O-CB 3.22Å; Y214-D218 PolarHBondContact O-N 2.82Å
215	L	70.1	Confident	65.4	Low	10 Å²	10	29 Å²	29	5%	0.052	15%	0.149	C	C	.	.	H	α-helix	trans	-57.6	-39.8	174.2	-175.1	60.2	0	0	0	111.6	M211 Y219 I235 T238 V239 L242 F318	M211-L215 WeakPolarHBondContact O-CB 3.4Å; M211-L215 PolarHBondContact O-N 2.92Å; L215-Y219 WeakPolarHBondContact O-CB 3.45Å; L215-Y219 PolarHBondContact O-N 2.84Å; L215-I235 HydrophobicContact CD1-CB 4.42Å; L215-I235 HydrophobicContact CD1-CG2 3.92Å; L215-T238 HydrophobicContact CB-CG2 3.73Å; L215-T238 HydrophobicContact CD1-CG2 4.16Å; L215-T238 HydrophobicContact CG-CG2 4.38Å; L215-V239 HydrophobicContact CD1-CG2 3.8Å; L215-V239 HydrophobicContact CD2-CG2 3.98Å; L215-L242 HydrophobicContact CD2-CD1 3.67Å; L215-F318 HydrophobicContact CB-CE1 4.43Å; L215-F318 HydrophobicContact CD2-CD1 3.72Å; L215-F318 HydrophobicContact CD2-CE1 3.53Å; L215-F318 HydrophobicContact CG-CD1 4.08Å; L215-F318 HydrophobicContact CG-CE1 3.55Å; L215-F318 HydrophobicContact CG-CZ 4.29Å
216	W	69.8	Low	65.1	Low	22 Å²	22	35.1 Å²	35.1	8%	0.083	18%	0.176	C	C	.	.	H	α-helix	trans	-64.6	-45.3	175.3	162	66.7	0	0	0	112.2	V212 Q213 Y214 Y219 R220 P311 H314 K315 F318	V212-W216 VanDerWaalsContact O-CB 3.3Å; V212-W216 WeakPolarHBondContact O-CB 3.38Å; V212-W216 PolarHBondContact O-N 3.49Å; Q213-W216 WeakPolarHBondContact O-CB 3.05Å; Q213-W216 PolarHBondContact O-N 3.42Å; Y214-W216 PolarHBondContact O-N 2.92Å; W216-Y219 PolarHBondContact O-N 3.14Å; W216-R220 PolarHBondContact O-N 3.22Å; W216-P311 HydrophobicContact CH2-CB 4.21Å; W216-P311 WeakPolarHBondContact CH2-O 3.4Å; W216-P311 HydrophobicContact CZ2-CB 4.39Å; W216-P311 WeakPolarHBondContact CZ2-O 3.44Å; W216-H314 VanDerWaalsContact NE1-CB 3.33Å; W216-K315 HydrophobicContact CD2-CD 4.25Å; W216-K315 HydrophobicContact CD2-CG 3.57Å; W216-K315 HydrophobicContact CE3-CD 4.29Å; W216-K315 VanDerWaalsContact CE3-CE 3.43Å; W216-K315 HydrophobicContact CE3-CG 4.12Å; W216-K315 HydrophobicContact CG-CG 3.7Å; W216-K315 HydrophobicContact CZ2-CG 4.47Å; W216-F318 HydrophobicContact CB-CD2 3.99Å; W216-F318 HydrophobicContact CB-CE2 4.03Å
217	V	64.2	Low	64.8	Low	27 Å²	27	36.3 Å²	36.3	16%	0.164	19%	0.185	C	C	.	.	H	α-helix	trans	-62.5	-48.6	176.4	174.1	0	0	0	0	110.7	Y167 Q213 Y214 Y219 R220 C221	Y167-V217 HydrophobicContact CD1-CG1 4.21Å; Y167-V217 HydrophobicContact CE1-CG1 4.41Å; Q213-V217 WeakPolarHBondContact O-CG2 3.13Å; Q213-V217 PolarHBondContact O-N 2.86Å; Y214-V217 PolarHBondContact O-N 3.41Å; Y214-V217 VanDerWaalsContact O-N 3.1Å; V217-Y219 VanDerWaalsContact C-N 3.34Å; V217-Y219 PolarHBondContact O-N 2.91Å; V217-R220 WeakPolarHBondContact O-CB 3.44Å; V217-R220 PolarHBondContact O-N 3.09Å; V217-R220 VanDerWaalsContact O-N 3.15Å; V217-C221 PolarHBondContact O-N 3.23Å; V217-C221 PolarHBondContact O-SG 3.21Å
218	D	64.2	Low	64.6	Low	19 Å²	19	41.6 Å²	41.6	10%	0.102	21%	0.21	C	C	.	.	H	α-helix	trans	-59.9	-45.1	178.7	-75.2	-35.6	0	0	0	111.6	Y214 R220 C221 A222 L231 N234 I235	Y214-D218 WeakPolarHBondContact O-CB 3.22Å; Y214-D218 PolarHBondContact O-N 2.82Å; D218-R220 VanDerWaalsContact C-N 3.32Å; D218-R220 PolarHBondContact O-N 3.23Å; D218-C221 PolarHBondContact O-N 3.45Å; D218-A222 WeakPolarHBondContact O-CB 3.18Å; D218-A222 PolarHBondContact O-N 3.24Å; D218-L231 HydrophobicContact CB-CD1 3.96Å; D218-N234 VanDerWaalsContact CG-ND2 3.26Å; D218-N234 PolarHBondContact OD1-ND2 2.86Å; D218-N234 PolarHBondContact OD2-ND2 3.4Å; D218-I235 HydrophobicContact CB-CD1 4.29Å; D218-I235 HydrophobicContact CB-CG1 3.63Å
219	Y	69	Low	64.4	Low	36 Å²	36	45 Å²	45	14%	0.141	23%	0.233	C	C	.	.	H	α-helix	trans	-56.6	-47	174.9	172.5	-105.6	0	0	0	110.8	L215 W216 V217 C221 A222 I223 S293 D296 F318	L215-Y219 WeakPolarHBondContact O-CB 3.45Å; L215-Y219 PolarHBondContact O-N 2.84Å; W216-Y219 PolarHBondContact O-N 3.14Å; V217-Y219 VanDerWaalsContact C-N 3.34Å; V217-Y219 PolarHBondContact O-N 2.91Å; Y219-C221 PolarHBondContact O-N 2.9Å; Y219-A222 PolarHBondContact O-N 3.1Å; Y219-I223 HydrophobicContact CD1-CD1 3.74Å; Y219-I223 HydrophobicContact CD2-CD1 3.72Å; Y219-I223 HydrophobicContact CE1-CD1 3.33Å; Y219-I223 HydrophobicContact CE2-CD1 3.29Å; Y219-I223 HydrophobicContact CE2-CG1 4.32Å; Y219-I223 HydrophobicContact CG-CD1 3.93Å; Y219-I223 VanDerWaalsContact O-CB 3.3Å; Y219-I223 WeakPolarHBondContact O-CB 3.35Å; Y219-I223 WeakPolarHBondContact O-CD1 3.34Å; Y219-I223 VanDerWaalsContact O-CG1 3.25Å; Y219-I223 WeakPolarHBondContact O-CG1 3.3Å; Y219-I223 PolarHBondContact O-N 3.5Å; Y219-I223 VanDerWaalsContact O-N 3.12Å; Y219-I223 WeakPolarHBondContact OH-CD1 3.39Å; Y219-S293 PolarHBondContact OH-O 3.37Å; Y219-D296 HydrophobicContact CE1-CB 4.33Å; Y219-D296 WeakPolarHBondContact OH-CB 3.16Å; Y219-F318 AromaticContact CD1-CE2 3.94Å; Y219-F318 HydrophobicContact CD1-CE2 3.94Å; Y219-F318 AromaticContact CD1-CZ 3.95Å; Y219-F318 HydrophobicContact CD1-CZ 3.95Å; Y219-F318 HydrophobicContact CD2-CZ 4.36Å; Y219-F318 HydrophobicContact CE1-CE2 4.49Å; Y219-F318 HydrophobicContact CG-CE2 4.26Å; Y219-F318 AromaticContact CG-CZ 3.8Å; Y219-F318 HydrophobicContact CG-CZ 3.8Å
220	R	63.1	Low	63.6	Low	47 Å²	47	47.8 Å²	47.8	18%	0.177	25%	0.249	C	C	.	.	H	α-helix	trans	-62.1	-43.8	177	-169.3	-176.3	-175.9	-165.2	-1.2	111.7	W216 V217 D218 A222 I223 V224 H307 V308	W216-R220 PolarHBondContact O-N 3.22Å; V217-R220 WeakPolarHBondContact O-CB 3.44Å; V217-R220 PolarHBondContact O-N 3.09Å; V217-R220 VanDerWaalsContact O-N 3.15Å; D218-R220 VanDerWaalsContact C-N 3.32Å; D218-R220 PolarHBondContact O-N 3.23Å; R220-A222 VanDerWaalsContact C-N 3.34Å; R220-I223 PolarHBondContact O-N 3.36Å; R220-V224 HydrophobicContact CG-CG2 4.4Å; R220-V224 WeakPolarHBondContact O-CB 3.4Å; R220-V224 VanDerWaalsContact O-CG2 3.29Å; R220-V224 WeakPolarHBondContact O-CG2 3.41Å; R220-V224 PolarHBondContact O-N 3.49Å; R220-H307 PolarHBondContact NH2-O 2.63Å; R220-V308 PolarHBondContact NH2-O 2.84Å; R220-V308 VanDerWaalsContact NH2-O 3.12Å
221	C	62.3	Low	63.4	Low	26 Å²	26	49 Å²	49	18%	0.176	26%	0.256	C	S	.	.	H	α-helix	trans	-63.1	-40.4	176.4	-74.3	0	0	0	0	111.7	V217 D218 Y219 I223 V224 L225 L231	V217-C221 PolarHBondContact O-N 3.23Å; V217-C221 PolarHBondContact O-SG 3.21Å; D218-C221 PolarHBondContact O-N 3.45Å; Y219-C221 PolarHBondContact O-N 2.9Å; C221-I223 PolarHBondContact O-N 3.01Å; C221-V224 PolarHBondContact O-N 3.46Å; C221-L225 HydrophobicContact CB-CD1 4.1Å; C221-L225 VanDerWaalsContact O-CB 3.28Å; C221-L225 WeakPolarHBondContact O-CB 3.35Å; C221-L225 PolarHBondContact O-N 3.49Å; C221-L231 HydrophobicContact CB-CD1 4.28Å; C221-L231 HydrophobicContact CB-CD2 3.85Å
222	A	65	Low	63.1	Low	11 Å²	11	55.2 Å²	55.2	9%	0.091	28%	0.28	C	S	.	.	H	α-helix	trans	-68.2	-28.1	-176.9	0	0	0	0	0	112.5	D218 Y219 R220 P227 L231 I235	D218-A222 WeakPolarHBondContact O-CB 3.18Å; D218-A222 PolarHBondContact O-N 3.24Å; Y219-A222 PolarHBondContact O-N 3.1Å; R220-A222 VanDerWaalsContact C-N 3.34Å; A222-P227 HydrophobicContact CB-CB 4.46Å; A222-L231 HydrophobicContact CB-CD2 3.75Å; A222-L231 HydrophobicContact CB-CG 3.96Å; A222-L231 VanDerWaalsContact N-CD2 3.34Å; A222-I235 HydrophobicContact CB-CD1 3.6Å
223	I	64	Low	62.2	Low	31 Å²	31	57.3 Å²	57.3	16%	0.159	30%	0.295	C	S	.	.	H	α-helix	trans	-81.2	-47.3	178.3	-80.4	176	0	0	0	110.8	Y219 R220 C221 V300 H307	Y219-I223 HydrophobicContact CD1-CD1 3.74Å; Y219-I223 HydrophobicContact CD2-CD1 3.72Å; Y219-I223 HydrophobicContact CE1-CD1 3.33Å; Y219-I223 HydrophobicContact CE2-CD1 3.29Å; Y219-I223 HydrophobicContact CE2-CG1 4.32Å; Y219-I223 HydrophobicContact CG-CD1 3.93Å; Y219-I223 VanDerWaalsContact O-CB 3.3Å; Y219-I223 WeakPolarHBondContact O-CB 3.35Å; Y219-I223 WeakPolarHBondContact O-CD1 3.34Å; Y219-I223 VanDerWaalsContact O-CG1 3.25Å; Y219-I223 WeakPolarHBondContact O-CG1 3.3Å; Y219-I223 PolarHBondContact O-N 3.5Å; Y219-I223 VanDerWaalsContact O-N 3.12Å; Y219-I223 WeakPolarHBondContact OH-CD1 3.39Å; R220-I223 PolarHBondContact O-N 3.36Å; C221-I223 PolarHBondContact O-N 3.01Å; I223-V300 HydrophobicContact CB-CG1 4.39Å; I223-V300 HydrophobicContact CB-CG2 4.38Å; I223-V300 HydrophobicContact CG2-CB 3.5Å; I223-V300 VanDerWaalsContact CG2-CB 3.5Å; I223-V300 HydrophobicContact CG2-CG1 3.39Å; I223-V300 HydrophobicContact CG2-CG2 2.91Å; I223-V300 WeakPolarHBondContact O-CG1 3.01Å; I223-H307 VanDerWaalsContact CG2-CE1 3.43Å; I223-H307 WeakPolarHBondContact CG2-CE1 3.35Å
224	V	58.2	Low	61.9	Low	84 Å²	84	59.1 Å²	59.1	51%	0.509	31%	0.305	S	S	.	.	H	α-helix	trans	-80.6	-37.5	-172.8	174.3	0	0	0	0	113.1	R220 C221 H307	R220-V224 HydrophobicContact CG-CG2 4.4Å; R220-V224 WeakPolarHBondContact O-CB 3.4Å; R220-V224 VanDerWaalsContact O-CG2 3.29Å; R220-V224 WeakPolarHBondContact O-CG2 3.41Å; R220-V224 PolarHBondContact O-N 3.49Å; C221-V224 PolarHBondContact O-N 3.46Å; V224-H307 WeakPolarHBondContact CG2-ND1 3.15Å
225	L	60.6	Low	61.9	Low	75 Å²	75	59.2 Å²	59.2	39%	0.393	31%	0.307	S	S	.	.	S	Bend	trans	-95.5	158.4	-175.2	-60.5	162.7	0	0	0	109.5	M163 C221 P227	M163-L225 HydrophobicContact CE-CD1 3.68Å; M163-L225 HydrophobicContact CE-CD2 4.21Å; M163-L225 HydrophobicContact SD-CD1 3.98Å; C221-L225 HydrophobicContact CB-CD1 4.1Å; C221-L225 VanDerWaalsContact O-CB 3.28Å; C221-L225 WeakPolarHBondContact O-CB 3.35Å; C221-L225 PolarHBondContact O-N 3.49Å; L225-P227 WeakPolarHBondContact O-CD 3.13Å
226	Q	59.3	Low	61.5	Low	182 Å²	182	61.5 Å²	61.5	85%	0.85	33%	0.328	S	S	*	.			trans	-61.1	106.4	163.2	-75.8	-175.6	-15.4	0	0	107.3	H228	Q226-H228 PolarHBondContact O-N 2.89Å
227	P	60	Low	61	Low	50 Å²	50	64.7 Å²	64.7	33%	0.325	35%	0.35	S	S	.	.			trans	-72	122.9	-164.8	25.5	-28.3	0	0	0	109.1	A222 L225 Y232	A222-P227 HydrophobicContact CB-CB 4.46Å; L225-P227 WeakPolarHBondContact O-CD 3.13Å; P227-Y232 HydrophobicContact CB-CD2 4.2Å; P227-Y232 HydrophobicContact CB-CE2 3.5Å; P227-Y232 HydrophobicContact CG-CE2 3.53Å; P227-Y232 WeakPolarHBondContact CG-OH 3.16Å
228	H	61.2	Low	61	Low	113 Å²	113	64.1 Å²	64.1	52%	0.523	35%	0.346	S	S	.	.			trans	-73.9	150.8	169.9	-78.5	-73.7	0	0	0	110.1	Q226 L230 L231 Y232	Q226-H228 PolarHBondContact O-N 2.89Å; H228-L230 PolarHBondContact O-N 3.46Å; H228-L230 VanDerWaalsContact O-N 3.09Å; H228-L231 WeakPolarHBondContact O-CB 3.33Å; H228-L231 PolarHBondContact O-N 3.15Å; H228-Y232 PolarHBondContact O-N 3.41Å
229	T	63	Low	61.2	Low	121 Å²	121	65.9 Å²	65.9	74%	0.742	36%	0.358	S	S	*	.	H	α-helix	trans	-52.3	-32.7	176.1	46	0	0	0	0	112.9	L231 Y232 S233	T229-L231 VanDerWaalsContact C-N 3.33Å; T229-L231 PolarHBondContact O-N 2.96Å; T229-Y232 PolarHBondContact O-N 3.06Å; T229-S233 PolarHBondContact O-N 2.9Å
230	L	51.5	Low	61	Low	82 Å²	82	71 Å²	71	43%	0.429	38%	0.381	S	S	.	.	H	α-helix	trans	-61.6	-37.7	174.7	-73.1	170.7	0	0	0	113.1	L156 H228 S233 N234	L156-L230 HydrophobicContact CD1-CD1 3.43Å; L156-L230 VanDerWaalsContact CD1-CD1 3.43Å; L156-L230 HydrophobicContact CG-CD1 4.46Å; H228-L230 PolarHBondContact O-N 3.46Å; H228-L230 VanDerWaalsContact O-N 3.09Å; L230-S233 WeakPolarHBondContact CA-OG 3.34Å; L230-S233 CarbonylContact O-C 3.6Å; L230-S233 PolarHBondContact O-N 3.29Å; L230-S233 PolarHBondContact O-OG 3.12Å; L230-N234 PolarHBondContact O-N 3.38Å
231	L	57.6	Low	61	Low	29 Å²	29	71.7 Å²	71.7	15%	0.152	39%	0.386	C	S	.	.	H	α-helix	trans	-70.1	-42.3	-178.9	-175.9	56.4	0	0	0	111.6	D218 C221 A222 H228 T229 S233 N234 I235	D218-L231 HydrophobicContact CB-CD1 3.96Å; C221-L231 HydrophobicContact CB-CD1 4.28Å; C221-L231 HydrophobicContact CB-CD2 3.85Å; A222-L231 HydrophobicContact CB-CD2 3.75Å; A222-L231 HydrophobicContact CB-CG 3.96Å; A222-L231 VanDerWaalsContact N-CD2 3.34Å; H228-L231 WeakPolarHBondContact O-CB 3.33Å; H228-L231 PolarHBondContact O-N 3.15Å; T229-L231 VanDerWaalsContact C-N 3.33Å; T229-L231 PolarHBondContact O-N 2.96Å; L231-S233 VanDerWaalsContact C-N 3.27Å; L231-S233 PolarHBondContact O-N 3.41Å; L231-N234 WeakPolarHBondContact O-CB 3.44Å; L231-N234 PolarHBondContact O-N 3.27Å; L231-N234 VanDerWaalsContact O-N 3.15Å; L231-I235 WeakPolarHBondContact O-CG1 3.5Å; L231-I235 PolarHBondContact O-N 3Å
232	Y	62.6	Low	61.3	Low	133 Å²	133	72.3 Å²	72.3	52%	0.522	39%	0.387	S	S	.	.	H	α-helix	trans	-62.6	-36	170.9	-72.4	-60.4	0	0	0	112.2	P227 H228 T229 N234 A236	P227-Y232 HydrophobicContact CB-CD2 4.2Å; P227-Y232 HydrophobicContact CB-CE2 3.5Å; P227-Y232 HydrophobicContact CG-CE2 3.53Å; P227-Y232 WeakPolarHBondContact CG-OH 3.16Å; H228-Y232 PolarHBondContact O-N 3.41Å; T229-Y232 PolarHBondContact O-N 3.06Å; Y232-N234 VanDerWaalsContact C-N 3.35Å; Y232-A236 VanDerWaalsContact O-CB 3.31Å; Y232-A236 WeakPolarHBondContact O-CB 3.43Å; Y232-A236 PolarHBondContact O-N 3.34Å
233	S	49.6	Very low	61.4	Low	57 Å²	57	78.7 Å²	78.7	40%	0.399	41%	0.413	S	S	.	.	H	α-helix	trans	-65.6	-38.4	173.6	79	0	0	0	0	111.9	T229 L230 L231 A236 V237	T229-S233 PolarHBondContact O-N 2.9Å; L230-S233 WeakPolarHBondContact CA-OG 3.34Å; L230-S233 CarbonylContact O-C 3.6Å; L230-S233 PolarHBondContact O-N 3.29Å; L230-S233 PolarHBondContact O-OG 3.12Å; L231-S233 VanDerWaalsContact C-N 3.27Å; L231-S233 PolarHBondContact O-N 3.41Å; S233-A236 PolarHBondContact O-N 3.37Å; S233-V237 WeakPolarHBondContact O-CB 3.37Å; S233-V237 WeakPolarHBondContact O-CG2 3.21Å; S233-V237 PolarHBondContact O-N 3.35Å
234	N	60.1	Low	61.4	Low	55 Å²	55	80.1 Å²	80.1	29%	0.294	42%	0.423	S	S	.	.	H	α-helix	trans	-64.4	-47.7	176.8	-157.4	24.9	0	0	0	111.1	D218 L230 L231 Y232 A236 V237 T238	D218-N234 VanDerWaalsContact CG-ND2 3.26Å; D218-N234 PolarHBondContact OD1-ND2 2.86Å; D218-N234 PolarHBondContact OD2-ND2 3.4Å; L230-N234 PolarHBondContact O-N 3.38Å; L231-N234 WeakPolarHBondContact O-CB 3.44Å; L231-N234 PolarHBondContact O-N 3.27Å; L231-N234 VanDerWaalsContact O-N 3.15Å; Y232-N234 VanDerWaalsContact C-N 3.35Å; N234-A236 VanDerWaalsContact C-N 3.35Å; N234-A236 PolarHBondContact O-N 3.13Å; N234-V237 PolarHBondContact O-N 3.29Å; N234-T238 WeakPolarHBondContact O-CB 3.25Å; N234-T238 PolarHBondContact O-N 3.08Å; N234-T238 PolarHBondContact O-OG1 3.42Å; N234-T238 VanDerWaalsContact O-OG1 3.06Å
235	I	64.9	Low	61.8	Low	33 Å²	33	76.3 Å²	76.3	17%	0.169	40%	0.4	C	S	.	.	H	α-helix	trans	-56.8	-48.8	174.4	-67.6	172.6	0	0	0	110.6	L215 D218 A222 L231 V237 T238 V239	L215-I235 HydrophobicContact CD1-CB 4.42Å; L215-I235 HydrophobicContact CD1-CG2 3.92Å; D218-I235 HydrophobicContact CB-CD1 4.29Å; D218-I235 HydrophobicContact CB-CG1 3.63Å; A222-I235 HydrophobicContact CB-CD1 3.6Å; L231-I235 WeakPolarHBondContact O-CG1 3.5Å; L231-I235 PolarHBondContact O-N 3Å; I235-V237 PolarHBondContact O-N 3.37Å; I235-T238 PolarHBondContact O-N 2.9Å; I235-V239 HydrophobicContact CG2-CG2 4.37Å; I235-V239 WeakPolarHBondContact O-CB 3.43Å; I235-V239 VanDerWaalsContact O-CG2 3.26Å; I235-V239 WeakPolarHBondContact O-CG2 3.49Å; I235-V239 PolarHBondContact O-N 2.95Å
236	A	62.6	Low	62.1	Low	59 Å²	59	76 Å²	76	49%	0.488	40%	0.396	S	S	.	.	H	α-helix	trans	-62.2	-42.3	-179.6	0	0	0	0	0	112.1	Y232 S233 N234 F240	Y232-A236 VanDerWaalsContact O-CB 3.31Å; Y232-A236 WeakPolarHBondContact O-CB 3.43Å; Y232-A236 PolarHBondContact O-N 3.34Å; S233-A236 PolarHBondContact O-N 3.37Å; N234-A236 VanDerWaalsContact C-N 3.35Å; N234-A236 PolarHBondContact O-N 3.13Å; A236-F240 VanDerWaalsContact O-CB 3.31Å; A236-F240 WeakPolarHBondContact O-CB 3.34Å; A236-F240 PolarHBondContact O-N 3.39Å
237	V	59.1	Low	62.4	Low	89 Å²	89	72.9 Å²	72.9	54%	0.539	38%	0.38	S	S	.	.	H	α-helix	trans	-63.7	-46.8	176.1	168.9	0	0	0	0	110.6	S233 N234 I235 F240 H241	S233-V237 WeakPolarHBondContact O-CB 3.37Å; S233-V237 WeakPolarHBondContact O-CG2 3.21Å; S233-V237 PolarHBondContact O-N 3.35Å; N234-V237 PolarHBondContact O-N 3.29Å; I235-V237 PolarHBondContact O-N 3.37Å; V237-F240 PolarHBondContact O-N 2.92Å; V237-H241 VanDerWaalsContact O-CB 3.28Å; V237-H241 WeakPolarHBondContact O-CB 3.21Å; V237-H241 PolarHBondContact O-N 3.29Å
238	T	63.4	Low	62.6	Low	15 Å²	15	72.3 Å²	72.3	9%	0.092	38%	0.375	C	S	.	.	H	α-helix	trans	-65.2	-41.2	179.9	-59.7	0	0	0	0	111.8	M211 L215 N234 I235 H241 L242	M211-T238 HydrophobicContact CB-CG2 4.42Å; L215-T238 HydrophobicContact CB-CG2 3.73Å; L215-T238 HydrophobicContact CD1-CG2 4.16Å; L215-T238 HydrophobicContact CG-CG2 4.38Å; N234-T238 WeakPolarHBondContact O-CB 3.25Å; N234-T238 PolarHBondContact O-N 3.08Å; N234-T238 PolarHBondContact O-OG1 3.42Å; N234-T238 VanDerWaalsContact O-OG1 3.06Å; I235-T238 PolarHBondContact O-N 2.9Å; T238-H241 PolarHBondContact O-N 3.41Å; T238-L242 WeakPolarHBondContact O-CG 3.39Å; T238-L242 PolarHBondContact O-N 3.42Å
239	V	67.7	Low	62.8	Low	56 Å²	56	68 Å²	68	34%	0.339	36%	0.357	S	S	.	.	H	α-helix	trans	-62	-46.3	173.5	170.5	0	0	0	0	111	L215 I235 H241 L242 F243	L215-V239 HydrophobicContact CD1-CG2 3.8Å; L215-V239 HydrophobicContact CD2-CG2 3.98Å; I235-V239 HydrophobicContact CG2-CG2 4.37Å; I235-V239 WeakPolarHBondContact O-CB 3.43Å; I235-V239 VanDerWaalsContact O-CG2 3.26Å; I235-V239 WeakPolarHBondContact O-CG2 3.49Å; I235-V239 PolarHBondContact O-N 2.95Å; V239-H241 VanDerWaalsContact C-N 3.33Å; V239-H241 PolarHBondContact O-N 2.91Å; V239-L242 PolarHBondContact O-N 2.95Å; V239-F243 HydrophobicContact CG1-CD2 4Å; V239-F243 HydrophobicContact CG1-CE2 3.73Å; V239-F243 WeakPolarHBondContact O-CD2 3.45Å; V239-F243 PolarHBondContact O-N 3.29Å; V239-F243 VanDerWaalsContact O-N 3.13Å
240	F	65	Low	62.8	Low	144 Å²	144	62.9 Å²	62.9	63%	0.632	33%	0.327	S	S	*	.	H	α-helix	trans	-61.3	-42.4	175.8	-180	-99.4	0	0	0	111.6	A236 V237 L242 F243 V244	A236-F240 VanDerWaalsContact O-CB 3.31Å; A236-F240 WeakPolarHBondContact O-CB 3.34Å; A236-F240 PolarHBondContact O-N 3.39Å; V237-F240 PolarHBondContact O-N 2.92Å; F240-L242 PolarHBondContact O-N 3.04Å; F240-F243 WeakPolarHBondContact O-CB 3.38Å; F240-F243 PolarHBondContact O-N 2.83Å; F240-F243 VanDerWaalsContact O-N 3.16Å; F240-V244 HydrophobicContact CD1-CG2 4.02Å; F240-V244 HydrophobicContact CE1-CG2 3.59Å; F240-V244 HydrophobicContact CE2-CG2 4.39Å; F240-V244 HydrophobicContact CZ-CG2 3.8Å; F240-V244 WeakPolarHBondContact O-CG2 3.4Å; F240-V244 PolarHBondContact O-N 3.46Å
241	H	63.9	Low	63.4	Low	60 Å²	60	64.2 Å²	64.2	28%	0.278	33%	0.329	S	S	.	.	H	α-helix	trans	-61.4	-43.5	177.2	-162.9	169.5	0	0	0	111.1	Y178 M211 V237 T238 V239 F243 V244 V245	Y178-H241 AromaticContact CD1-CE1 3.58Å; Y178-H241 AromaticContact CD1-NE2 3.9Å; Y178-H241 AromaticContact CG-CE1 3.83Å; M211-H241 HydrophobicContact SD-CB 4.12Å; V237-H241 VanDerWaalsContact O-CB 3.28Å; V237-H241 WeakPolarHBondContact O-CB 3.21Å; V237-H241 PolarHBondContact O-N 3.29Å; T238-H241 PolarHBondContact O-N 3.41Å; V239-H241 VanDerWaalsContact C-N 3.33Å; V239-H241 PolarHBondContact O-N 2.91Å; H241-F243 VanDerWaalsContact C-N 3.32Å; H241-F243 PolarHBondContact O-N 3.48Å; H241-V244 PolarHBondContact O-N 3.43Å; H241-V245 VanDerWaalsContact CD2-CG2 3.41Å; H241-V245 WeakPolarHBondContact CD2-CG2 3.24Å; H241-V245 WeakPolarHBondContact O-CB 3.46Å; H241-V245 VanDerWaalsContact O-CG2 3.32Å; H241-V245 WeakPolarHBondContact O-CG2 3.29Å; H241-V245 PolarHBondContact O-N 3.34Å
242	L	67.2	Low	63.7	Low	39 Å²	39	63.6 Å²	63.6	20%	0.204	33%	0.326	C	S	.	.	H	α-helix	trans	-58.2	-41.5	173.6	-76.4	171.1	0	0	0	112.4	I208 M211 V212 L215 T238 V239 F240 F246	I208-L242 HydrophobicContact CG2-CD2 4.38Å; M211-L242 HydrophobicContact CB-CD2 3.67Å; M211-L242 HydrophobicContact CB-CG 4.17Å; M211-L242 HydrophobicContact CE-CD2 4.21Å; M211-L242 HydrophobicContact CG-CD2 4.41Å; M211-L242 HydrophobicContact SD-CD2 3.93Å; M211-L242 HydrophobicContact SD-CG 4.22Å; V212-L242 HydrophobicContact CG2-CD2 4.27Å; L215-L242 HydrophobicContact CD2-CD1 3.67Å; T238-L242 WeakPolarHBondContact O-CG 3.39Å; T238-L242 PolarHBondContact O-N 3.42Å; V239-L242 PolarHBondContact O-N 2.95Å; F240-L242 PolarHBondContact O-N 3.04Å; L242-F246 VanDerWaalsContact O-CB 3.28Å; L242-F246 WeakPolarHBondContact O-CB 3.43Å; L242-F246 PolarHBondContact O-N 3.36Å
243	F	68.7	Low	63.6	Low	145 Å²	145	57.4 Å²	57.4	64%	0.636	30%	0.302	S	S	*	.	H	α-helix	trans	-64.4	-43.9	174.6	-81	-68.3	0	0	0	112.6	V239 F240 H241 F246 F247	V239-F243 HydrophobicContact CG1-CD2 4Å; V239-F243 HydrophobicContact CG1-CE2 3.73Å; V239-F243 WeakPolarHBondContact O-CD2 3.45Å; V239-F243 PolarHBondContact O-N 3.29Å; V239-F243 VanDerWaalsContact O-N 3.13Å; F240-F243 WeakPolarHBondContact O-CB 3.38Å; F240-F243 PolarHBondContact O-N 2.83Å; F240-F243 VanDerWaalsContact O-N 3.16Å; H241-F243 VanDerWaalsContact C-N 3.32Å; H241-F243 PolarHBondContact O-N 3.48Å; F243-F246 PolarHBondContact O-N 2.94Å; F243-F247 WeakPolarHBondContact O-CB 3.48Å; F243-F247 PolarHBondContact O-N 3.21Å
244	V	63.5	Low	64.1	Low	61 Å²	61	59.1 Å²	59.1	37%	0.37	30%	0.302	S	S	.	.	H	α-helix	trans	-62.8	-49.7	177.1	172.3	0	0	0	0	110.3	F240 H241 F246 F247 V248	F240-V244 HydrophobicContact CD1-CG2 4.02Å; F240-V244 HydrophobicContact CE1-CG2 3.59Å; F240-V244 HydrophobicContact CE2-CG2 4.39Å; F240-V244 HydrophobicContact CZ-CG2 3.8Å; F240-V244 WeakPolarHBondContact O-CG2 3.4Å; F240-V244 PolarHBondContact O-N 3.46Å; H241-V244 PolarHBondContact O-N 3.43Å; V244-F246 VanDerWaalsContact C-N 3.33Å; V244-F246 PolarHBondContact O-N 2.87Å; V244-F247 WeakPolarHBondContact O-CB 3.24Å; V244-F247 PolarHBondContact O-N 3.09Å; V244-F247 VanDerWaalsContact O-N 3.09Å; V244-V248 HydrophobicContact CG1-CG2 4.19Å; V244-V248 VanDerWaalsContact O-CG2 3.31Å; V244-V248 WeakPolarHBondContact O-CG2 3.14Å; V244-V248 PolarHBondContact O-N 2.96Å
245	V	66.1	Low	64.1	Low	5 Å²	5	58.5 Å²	58.5	3%	0.03	31%	0.305	C	S	.	.	H	α-helix	trans	-57.7	-46.8	177.6	163.8	0	0	0	0	110.3	L204 I208 M211 H241 F247 V248 V249	L204-V245 HydrophobicContact CD1-CB 4.1Å; L204-V245 HydrophobicContact CD1-CG1 3.64Å; L204-V245 HydrophobicContact CD1-CG2 3.8Å; L204-V245 HydrophobicContact CG-CG1 3.9Å; I208-V245 HydrophobicContact CD1-CG1 4.06Å; I208-V245 HydrophobicContact CG1-CG1 3.65Å; M211-V245 HydrophobicContact CE-CB 3.84Å; M211-V245 HydrophobicContact CE-CG1 3.76Å; M211-V245 HydrophobicContact CE-CG2 3.4Å; M211-V245 VanDerWaalsContact CE-CG2 3.4Å; M211-V245 HydrophobicContact SD-CG2 4.07Å; H241-V245 VanDerWaalsContact CD2-CG2 3.41Å; H241-V245 WeakPolarHBondContact CD2-CG2 3.24Å; H241-V245 WeakPolarHBondContact O-CB 3.46Å; H241-V245 VanDerWaalsContact O-CG2 3.32Å; H241-V245 WeakPolarHBondContact O-CG2 3.29Å; H241-V245 PolarHBondContact O-N 3.34Å; V245-F247 VanDerWaalsContact C-N 3.32Å; V245-F247 PolarHBondContact O-N 3.08Å; V245-V248 PolarHBondContact O-N 3.42Å; V245-V249 HydrophobicContact CG1-CG2 4.22Å; V245-V249 WeakPolarHBondContact O-CB 3.46Å; V245-V249 VanDerWaalsContact O-CG2 3.27Å; V245-V249 WeakPolarHBondContact O-CG2 3.16Å; V245-V249 PolarHBondContact O-N 3.2Å
246	F	66.4	Low	63.9	Low	68 Å²	68	57.1 Å²	57.1	30%	0.298	30%	0.298	S	S	.	.	H	α-helix	trans	-58	-44.1	175.1	173.7	-88.9	0	0	0	112.4	L242 F243 V244 A250 F326	L242-F246 VanDerWaalsContact O-CB 3.28Å; L242-F246 WeakPolarHBondContact O-CB 3.43Å; L242-F246 PolarHBondContact O-N 3.36Å; F243-F246 PolarHBondContact O-N 2.94Å; V244-F246 VanDerWaalsContact C-N 3.33Å; V244-F246 PolarHBondContact O-N 2.87Å; F246-A250 WeakPolarHBondContact O-CB 3.37Å; F246-A250 PolarHBondContact O-N 3.31Å; F246-F326 HydrophobicContact CD2-CD1 4.43Å; F246-F326 AromaticContact CD2-CE1 3.45Å; F246-F326 HydrophobicContact CD2-CE1 3.45Å; F246-F326 VanDerWaalsContact CD2-CE1 3.45Å; F246-F326 AromaticContact CD2-CZ 3.49Å; F246-F326 HydrophobicContact CD2-CZ 3.49Å; F246-F326 VanDerWaalsContact CD2-CZ 3.49Å; F246-F326 AromaticContact CE2-CD1 3.74Å; F246-F326 HydrophobicContact CE2-CD1 3.74Å; F246-F326 AromaticContact CE2-CE1 3.14Å; F246-F326 HydrophobicContact CE2-CE1 3.14Å; F246-F326 AromaticContact CE2-CZ 3.64Å; F246-F326 HydrophobicContact CE2-CZ 3.64Å; F246-F326 HydrophobicContact CZ-CE1 4.37Å
247	F	66.1	Low	63.6	Low	117 Å²	117	55 Å²	55	51%	0.513	28%	0.279	S	S	.	.	H	α-helix	trans	-64.8	-43.2	178.3	-175.5	-94.9	0	0	0	111.8	F243 V244 V245 A250 K251	F243-F247 WeakPolarHBondContact O-CB 3.48Å; F243-F247 PolarHBondContact O-N 3.21Å; V244-F247 WeakPolarHBondContact O-CB 3.24Å; V244-F247 PolarHBondContact O-N 3.09Å; V244-F247 VanDerWaalsContact O-N 3.09Å; V245-F247 VanDerWaalsContact C-N 3.32Å; V245-F247 PolarHBondContact O-N 3.08Å; F247-A250 PolarHBondContact O-N 3Å; F247-K251 HydrophobicContact CD1-CG 4.04Å; F247-K251 HydrophobicContact CE1-CD 4.38Å; F247-K251 HydrophobicContact CE1-CG 3.79Å; F247-K251 HydrophobicContact CZ-CD 4.34Å; F247-K251 HydrophobicContact CZ-CG 4.14Å; F247-K251 WeakPolarHBondContact O-CB 3.45Å; F247-K251 VanDerWaalsContact O-CG 3.25Å; F247-K251 WeakPolarHBondContact O-CG 2.88Å; F247-K251 PolarHBondContact O-N 3.39Å
248	V	64.6	Low	63.5	Low	38 Å²	38	57.9 Å²	57.9	23%	0.23	28%	0.284	C	S	.	.	H	α-helix	trans	-66.4	-45	177.3	177.2	0	0	0	0	110.6	T185 L204 V244 V245 A250 K251 L252	T185-V248 HydrophobicContact CG2-CG1 3.56Å; L204-V248 HydrophobicContact CD2-CB 3.94Å; L204-V248 HydrophobicContact CD2-CG1 3.6Å; V244-V248 HydrophobicContact CG1-CG2 4.19Å; V244-V248 VanDerWaalsContact O-CG2 3.31Å; V244-V248 WeakPolarHBondContact O-CG2 3.14Å; V244-V248 PolarHBondContact O-N 2.96Å; V245-V248 PolarHBondContact O-N 3.42Å; V248-A250 VanDerWaalsContact C-N 3.33Å; V248-A250 PolarHBondContact O-N 2.83Å; V248-K251 PolarHBondContact O-N 3.41Å; V248-L252 VanDerWaalsContact O-CB 3.25Å; V248-L252 WeakPolarHBondContact O-CB 3.49Å; V248-L252 PolarHBondContact O-N 3.36Å
249	V	64.9	Low	63	Low	22 Å²	22	59.9 Å²	59.9	13%	0.133	29%	0.294	C	S	.	.	H	α-helix	trans	-52.7	-55.7	172.4	168.6	0	0	0	0	108.1	L201 L204 I208 V245 K251 L252 T253	L201-V249 HydrophobicContact CD1-CG1 4.03Å; L204-V249 HydrophobicContact CB-CG2 4.36Å; L204-V249 HydrophobicContact CD2-CB 4.09Å; L204-V249 HydrophobicContact CD2-CG2 3.29Å; L204-V249 HydrophobicContact CG-CG2 3.54Å; I208-V249 HydrophobicContact CD1-CG2 4.45Å; V245-V249 HydrophobicContact CG1-CG2 4.22Å; V245-V249 WeakPolarHBondContact O-CB 3.46Å; V245-V249 VanDerWaalsContact O-CG2 3.27Å; V245-V249 WeakPolarHBondContact O-CG2 3.16Å; V245-V249 PolarHBondContact O-N 3.2Å; V249-K251 VanDerWaalsContact C-N 3.3Å; V249-K251 PolarHBondContact O-N 2.9Å; V249-L252 PolarHBondContact O-N 3.47Å; V249-T253 WeakPolarHBondContact O-CB 3.46Å; V249-T253 PolarHBondContact O-N 3.01Å; V249-T253 PolarHBondContact O-OG1 3Å; V249-T253 VanDerWaalsContact O-OG1 3.08Å
250	A	63.5	Low	62.2	Low	14 Å²	14	57.5 Å²	57.5	12%	0.116	28%	0.281	C	S	.	.	H	α-helix	trans	-60	-36.5	-177.5	0	0	0	0	0	113.4	F246 F247 V248 K254	F246-A250 WeakPolarHBondContact O-CB 3.37Å; F246-A250 PolarHBondContact O-N 3.31Å; F247-A250 PolarHBondContact O-N 3Å; V248-A250 VanDerWaalsContact C-N 3.33Å; V248-A250 PolarHBondContact O-N 2.83Å; A250-K254 VanDerWaalsContact O-CB 3.31Å; A250-K254 WeakPolarHBondContact O-CB 3.48Å; A250-K254 PolarHBondContact O-N 3.37Å
251	K	64.5	Low	61.7	Low	110 Å²	110	52 Å²	52	48%	0.478	26%	0.257	S	S	.	.	H	α-helix	trans	-74.7	-45.9	178	-74.1	-76	-172.3	164.3	0	112.4	F247 V248 V249 K254 A255	F247-K251 HydrophobicContact CD1-CG 4.04Å; F247-K251 HydrophobicContact CE1-CD 4.38Å; F247-K251 HydrophobicContact CE1-CG 3.79Å; F247-K251 HydrophobicContact CZ-CD 4.34Å; F247-K251 HydrophobicContact CZ-CG 4.14Å; F247-K251 WeakPolarHBondContact O-CB 3.45Å; F247-K251 VanDerWaalsContact O-CG 3.25Å; F247-K251 WeakPolarHBondContact O-CG 2.88Å; F247-K251 PolarHBondContact O-N 3.39Å; V248-K251 PolarHBondContact O-N 3.41Å; V249-K251 VanDerWaalsContact C-N 3.3Å; V249-K251 PolarHBondContact O-N 2.9Å; K251-K254 CarbonylContact O-C 3.59Å; K251-K254 WeakPolarHBondContact O-CA 3.46Å; K251-K254 WeakPolarHBondContact O-CB 3.36Å; K251-K254 PolarHBondContact O-N 3.24Å; K251-K254 VanDerWaalsContact O-N 3.09Å; K251-A255 PolarHBondContact O-N 2.97Å
252	L	64	Low	61	Low	15 Å²	15	52.6 Å²	52.6	8%	0.079	27%	0.266	C	S	.	.	H	α-helix	trans	-65.5	-44.4	178.9	-170.1	65.8	0	0	0	110.4	T185 A188 A197 L201 V248 V249 K254 A255 I256	T185-L252 HydrophobicContact CG2-CD2 4.13Å; A188-L252 HydrophobicContact CB-CD1 3.87Å; A197-L252 HydrophobicContact CB-CD1 3.68Å; A197-L252 HydrophobicContact CB-CG 4.29Å; L201-L252 HydrophobicContact CB-CD2 3.8Å; V248-L252 VanDerWaalsContact O-CB 3.25Å; V248-L252 WeakPolarHBondContact O-CB 3.49Å; V248-L252 PolarHBondContact O-N 3.36Å; V249-L252 PolarHBondContact O-N 3.47Å; L252-K254 VanDerWaalsContact C-N 3.31Å; L252-K254 PolarHBondContact O-N 3.25Å; L252-A255 WeakPolarHBondContact O-CB 3.3Å; L252-A255 PolarHBondContact O-N 2.95Å; L252-A255 VanDerWaalsContact O-N 3.08Å; L252-I256 HydrophobicContact CG-CD1 4.08Å; L252-I256 WeakPolarHBondContact O-CG1 3.4Å; L252-I256 PolarHBondContact O-N 2.8Å
253	T	59.7	Low	60.3	Low	4 Å²	4	53.2 Å²	53.2	3%	0.025	27%	0.265	C	S	.	.	H	α-helix	trans	-50.4	-48.8	165.9	-83.5	0	0	0	0	111.8	V249 A255 I256 S257 Y339	V249-T253 WeakPolarHBondContact O-CB 3.46Å; V249-T253 PolarHBondContact O-N 3.01Å; V249-T253 PolarHBondContact O-OG1 3Å; V249-T253 VanDerWaalsContact O-OG1 3.08Å; T253-A255 VanDerWaalsContact C-N 3.28Å; T253-A255 PolarHBondContact O-N 2.93Å; T253-I256 PolarHBondContact O-N 3.5Å; T253-S257 VanDerWaalsContact O-CB 3.24Å; T253-S257 WeakPolarHBondContact O-CB 3.42Å; T253-S257 PolarHBondContact O-N 2.83Å; T253-S257 PolarHBondContact O-OG 3.21Å; T253-Y339 HydrophobicContact CG2-CD1 4.3Å; T253-Y339 HydrophobicContact CG2-CD2 3.15Å; T253-Y339 HydrophobicContact CG2-CE1 4.17Å; T253-Y339 HydrophobicContact CG2-CE2 3.02Å; T253-Y339 HydrophobicContact CG2-CG 3.82Å
254	K	60.5	Low	59	Low	92 Å²	92	50.8 Å²	50.8	40%	0.4	27%	0.266	S	S	.	.	H	α-helix	trans	-65	-32.7	178.9	-177.5	-178	177.6	-176.1	0	112	A250 K251 L252 S257 K258	A250-K254 VanDerWaalsContact O-CB 3.31Å; A250-K254 WeakPolarHBondContact O-CB 3.48Å; A250-K254 PolarHBondContact O-N 3.37Å; K251-K254 CarbonylContact O-C 3.59Å; K251-K254 WeakPolarHBondContact O-CA 3.46Å; K251-K254 WeakPolarHBondContact O-CB 3.36Å; K251-K254 PolarHBondContact O-N 3.24Å; K251-K254 VanDerWaalsContact O-N 3.09Å; L252-K254 VanDerWaalsContact C-N 3.31Å; L252-K254 PolarHBondContact O-N 3.25Å; K254-S257 WeakPolarHBondContact CA-OG 3.39Å; K254-S257 PolarHBondContact O-OG 3.32Å; K254-K258 VanDerWaalsContact O-CG 3.3Å; K254-K258 WeakPolarHBondContact O-CG 3.39Å; K254-K258 PolarHBondContact O-N 3.01Å
255	A	60.7	Low	58.1	Low	42 Å²	42	54.6 Å²	54.6	35%	0.347	29%	0.285	S	S	.	.	H	α-helix	trans	-71.3	-49.4	175.9	0	0	0	0	0	111	K251 L252 T253 S257 K258 L259	K251-A255 PolarHBondContact O-N 2.97Å; L252-A255 WeakPolarHBondContact O-CB 3.3Å; L252-A255 PolarHBondContact O-N 2.95Å; L252-A255 VanDerWaalsContact O-N 3.08Å; T253-A255 VanDerWaalsContact C-N 3.28Å; T253-A255 PolarHBondContact O-N 2.93Å; A255-S257 VanDerWaalsContact C-N 3.28Å; A255-S257 PolarHBondContact O-N 3.44Å; A255-K258 PolarHBondContact O-N 3.15Å; A255-L259 WeakPolarHBondContact O-CB 3.49Å; A255-L259 WeakPolarHBondContact O-CD1 3.32Å; A255-L259 VanDerWaalsContact O-CG 3.31Å; A255-L259 WeakPolarHBondContact O-CG 3.43Å; A255-L259 PolarHBondContact O-N 2.77Å; A255-L259 VanDerWaalsContact O-N 3.08Å
256	I	59.8	Low	57.5	Low	5 Å²	5	57.7 Å²	57.7	3%	0.026	30%	0.301	C	S	.	.	H	α-helix	trans	-59.2	-42.5	175.2	-66.8	164.1	0	0	0	110.2	A197 F198 L201 L252 T253 L259 A260	A197-I256 HydrophobicContact CB-CD1 3.95Å; A197-I256 HydrophobicContact CB-CG1 3.63Å; F198-I256 HydrophobicContact CD1-CG2 4.44Å; F198-I256 HydrophobicContact CE1-CG2 3.74Å; F198-I256 HydrophobicContact CE2-CG2 3.97Å; F198-I256 HydrophobicContact CZ-CG2 3.47Å; F198-I256 VanDerWaalsContact CZ-CG2 3.47Å; L201-I256 HydrophobicContact CB-CD1 3.96Å; L201-I256 HydrophobicContact CD2-CD1 3.76Å; L201-I256 HydrophobicContact CG-CD1 4.43Å; L252-I256 HydrophobicContact CG-CD1 4.08Å; L252-I256 WeakPolarHBondContact O-CG1 3.4Å; L252-I256 PolarHBondContact O-N 2.8Å; T253-I256 PolarHBondContact O-N 3.5Å; I256-L259 PolarHBondContact O-N 3.26Å; I256-L259 VanDerWaalsContact O-N 3.15Å; I256-A260 HydrophobicContact CG2-CB 4.37Å; I256-A260 VanDerWaalsContact O-CB 3.24Å; I256-A260 WeakPolarHBondContact O-CB 3.47Å; I256-A260 PolarHBondContact O-N 3.28Å
257	S	55.5	Low	56.9	Low	13 Å²	13	63.6 Å²	63.6	9%	0.091	32%	0.321	C	S	.	.	H	α-helix	trans	-60.4	-55.5	179.6	75.4	0	0	0	0	109.4	T253 K254 A255 L259 A260 F261 W263	T253-S257 VanDerWaalsContact O-CB 3.24Å; T253-S257 WeakPolarHBondContact O-CB 3.42Å; T253-S257 PolarHBondContact O-N 2.83Å; T253-S257 PolarHBondContact O-OG 3.21Å; K254-S257 WeakPolarHBondContact CA-OG 3.39Å; K254-S257 PolarHBondContact O-OG 3.32Å; A255-S257 VanDerWaalsContact C-N 3.28Å; A255-S257 PolarHBondContact O-N 3.44Å; S257-L259 PolarHBondContact O-N 2.86Å; S257-A260 PolarHBondContact O-N 2.9Å; S257-F261 PolarHBondContact O-N 3.46Å; S257-W263 VanDerWaalsContact CB-NE1 3.3Å; S257-W263 PolarHBondContact O-NE1 2.86Å
258	K	57.4	Low	56.8	Low	151 Å²	151	59.6 Å²	59.6	66%	0.657	31%	0.305	S	S	*	.	H	α-helix	trans	-51.5	-31.5	175.3	-76.4	179.7	168.8	-159.3	0	114.7	K254 A255	K254-K258 VanDerWaalsContact O-CG 3.3Å; K254-K258 WeakPolarHBondContact O-CG 3.39Å; K254-K258 PolarHBondContact O-N 3.01Å; A255-K258 PolarHBondContact O-N 3.15Å
259	L	53	Low	56.9	Low	56 Å²	56	65.5 Å²	65.5	29%	0.293	34%	0.335	S	S	.	.	H	α-helix	trans	-88.4	-32.9	-176.7	-73.3	162.8	0	0	0	114.1	R194 A255 I256 S257	R194-L259 HydrophobicContact CG-CB 4.2Å; R194-L259 HydrophobicContact CG-CD1 4.07Å; R194-L259 HydrophobicContact CG-CD2 4.5Å; R194-L259 HydrophobicContact CG-CG 4.5Å; A255-L259 WeakPolarHBondContact O-CB 3.49Å; A255-L259 WeakPolarHBondContact O-CD1 3.32Å; A255-L259 VanDerWaalsContact O-CG 3.31Å; A255-L259 WeakPolarHBondContact O-CG 3.43Å; A255-L259 PolarHBondContact O-N 2.77Å; A255-L259 VanDerWaalsContact O-N 3.08Å; I256-L259 PolarHBondContact O-N 3.26Å; I256-L259 VanDerWaalsContact O-N 3.15Å; S257-L259 PolarHBondContact O-N 2.86Å
260	A	51	Low	57.2	Low	7 Å²	7	65.6 Å²	65.6	6%	0.058	34%	0.336	C	S	.	.	H	α-helix	trans	-100.5	-24.2	-168.5	0	0	0	0	0	113.8	F198 I256 S257 L586	F198-A260 HydrophobicContact CZ-CB 4.19Å; I256-A260 HydrophobicContact CG2-CB 4.37Å; I256-A260 VanDerWaalsContact O-CB 3.24Å; I256-A260 WeakPolarHBondContact O-CB 3.47Å; I256-A260 PolarHBondContact O-N 3.28Å; S257-A260 PolarHBondContact O-N 2.9Å; A260-L586 WeakPolarHBondContact O-CD1 3.38Å
261	F	54.8	Low	58.1	Low	29 Å²	29	69.9 Å²	69.9	13%	0.127	36%	0.358	C	S	.	.			trans	-143.3	140.9	170.8	-50.1	-104.8	0	0	0	108.1	S257 W263 I428 I580	S257-F261 PolarHBondContact O-N 3.46Å; F261-W263 HydrophobicContact CB-CD2 4.12Å; F261-W263 HydrophobicContact CB-CG 4.08Å; F261-W263 HydrophobicContact CB-CZ2 4.27Å; F261-W263 VanDerWaalsContact CB-NE1 3.3Å; F261-W263 AromaticContact CD2-CE2 3.48Å; F261-W263 VanDerWaalsContact CD2-CE2 3.48Å; F261-W263 HydrophobicContact CD2-CH2 4.16Å; F261-W263 AromaticContact CD2-CZ2 3.21Å; F261-W263 HydrophobicContact CD2-CZ2 3.21Å; F261-W263 AromaticContact CD2-NE1 3.56Å; F261-W263 HydrophobicContact CE2-CH2 4.47Å; F261-W263 AromaticContact CE2-CZ2 3.78Å; F261-W263 HydrophobicContact CE2-CZ2 3.78Å; F261-W263 AromaticContact CG-CE2 3.84Å; F261-W263 AromaticContact CG-CZ2 3.93Å; F261-W263 HydrophobicContact CG-CZ2 3.93Å; F261-W263 AromaticContact CG-NE1 3.84Å; F261-W263 PolarHBondContact O-N 3.49Å; F261-W263 PolarHBondContact O-NE1 3.34Å; F261-I428 HydrophobicContact CE1-CD1 4.14Å; F261-I580 HydrophobicContact CZ-CG1 4.02Å
262	P	49.6	Very low	59.2	Low	72 Å²	72	73.2 Å²	73.2	47%	0.468	37%	0.372	S	S	.	.			trans	-68.9	79.6	159.9	25.2	-27.9	0	0	0	108.1	S264	P262-S264 PolarHBondContact O-N 3.48Å
263	W	51.3	Low	60.3	Low	51 Å²	51	80.5 Å²	80.5	19%	0.193	40%	0.403	C	S	.	.	G	3₁₀ helix	trans	-66.3	15.5	-179.1	-57.5	80.3	0	0	0	113.6	S257 F261 N265 L266 F338	S257-W263 VanDerWaalsContact CB-NE1 3.3Å; S257-W263 PolarHBondContact O-NE1 2.86Å; F261-W263 HydrophobicContact CB-CD2 4.12Å; F261-W263 HydrophobicContact CB-CG 4.08Å; F261-W263 HydrophobicContact CB-CZ2 4.27Å; F261-W263 VanDerWaalsContact CB-NE1 3.3Å; F261-W263 AromaticContact CD2-CE2 3.48Å; F261-W263 VanDerWaalsContact CD2-CE2 3.48Å; F261-W263 HydrophobicContact CD2-CH2 4.16Å; F261-W263 AromaticContact CD2-CZ2 3.21Å; F261-W263 HydrophobicContact CD2-CZ2 3.21Å; F261-W263 AromaticContact CD2-NE1 3.56Å; F261-W263 HydrophobicContact CE2-CH2 4.47Å; F261-W263 AromaticContact CE2-CZ2 3.78Å; F261-W263 HydrophobicContact CE2-CZ2 3.78Å; F261-W263 AromaticContact CG-CE2 3.84Å; F261-W263 AromaticContact CG-CZ2 3.93Å; F261-W263 HydrophobicContact CG-CZ2 3.93Å; F261-W263 AromaticContact CG-NE1 3.84Å; F261-W263 PolarHBondContact O-N 3.49Å; F261-W263 PolarHBondContact O-NE1 3.34Å; W263-N265 PolarHBondContact O-N 2.89Å; W263-L266 HydrophobicContact CE3-CB 4.08Å; W263-L266 HydrophobicContact CE3-CD1 4.24Å; W263-L266 HydrophobicContact CE3-CD2 3.48Å; W263-L266 VanDerWaalsContact CE3-CD2 3.48Å; W263-L266 HydrophobicContact CE3-CG 4.13Å; W263-L266 HydrophobicContact CZ3-CD2 3.45Å; W263-L266 VanDerWaalsContact CZ3-CD2 3.45Å; W263-L266 PolarHBondContact O-N 3.36Å; W263-F338 HydrophobicContact CH2-CB 4.23Å; W263-F338 AromaticContact CH2-CD1 3.86Å; W263-F338 HydrophobicContact CH2-CD1 3.86Å; W263-F338 AromaticContact CH2-CD2 3.34Å; W263-F338 HydrophobicContact CH2-CD2 3.34Å; W263-F338 AromaticContact CH2-CE1 3.97Å; W263-F338 HydrophobicContact CH2-CE1 3.97Å; W263-F338 AromaticContact CH2-CE2 3.5Å; W263-F338 HydrophobicContact CH2-CE2 3.5Å; W263-F338 AromaticContact CH2-CG 3.53Å; W263-F338 HydrophobicContact CH2-CG 3.53Å; W263-F338 AromaticContact CH2-CZ 3.82Å; W263-F338 HydrophobicContact CH2-CZ 3.82Å; W263-F338 HydrophobicContact CZ3-CB 3.87Å; W263-F338 HydrophobicContact CZ3-CD1 4.36Å; W263-F338 AromaticContact CZ3-CD2 3.35Å; W263-F338 HydrophobicContact CZ3-CD2 3.35Å; W263-F338 AromaticContact CZ3-CE2 3.94Å; W263-F338 HydrophobicContact CZ3-CE2 3.94Å; W263-F338 AromaticContact CZ3-CG 3.59Å; W263-F338 HydrophobicContact CZ3-CG 3.59Å
264	S	42	Very low	61.6	Low	95 Å²	95	82.9 Å²	82.9	66%	0.664	42%	0.415	S	S	*	.	G	3₁₀ helix	trans	-56.2	-19.8	-179.5	55.2	0	0	0	0	112.5	P262	P262-S264 PolarHBondContact O-N 3.48Å
265	N	45	Very low	62.8	Low	141 Å²	141	84.6 Å²	84.6	75%	0.754	42%	0.419	S	S	*	.	G	3₁₀ helix	trans	-112.1	0.9	-175.2	-60.4	-12.9	0	0	0	115.1	W263 R267	W263-N265 PolarHBondContact O-N 2.89Å; N265-R267 VanDerWaalsContact C-N 3.34Å; N265-R267 PolarHBondContact O-N 3.41Å
266	L	53.4	Low	64.2	Low	70 Å²	70	86.4 Å²	86.4	37%	0.366	43%	0.429	S	S	.	.			trans	-82.5	81.1	177.2	-100.3	84.7	0	0	0	110.9	W263 Y426	W263-L266 HydrophobicContact CE3-CB 4.08Å; W263-L266 HydrophobicContact CE3-CD1 4.24Å; W263-L266 HydrophobicContact CE3-CD2 3.48Å; W263-L266 VanDerWaalsContact CE3-CD2 3.48Å; W263-L266 HydrophobicContact CE3-CG 4.13Å; W263-L266 HydrophobicContact CZ3-CD2 3.45Å; W263-L266 VanDerWaalsContact CZ3-CD2 3.45Å; W263-L266 PolarHBondContact O-N 3.36Å; L266-Y426 HydrophobicContact CD2-CD1 3.44Å; L266-Y426 VanDerWaalsContact CD2-CD1 3.44Å; L266-Y426 HydrophobicContact CD2-CE1 3.71Å; L266-Y426 HydrophobicContact CG-CD1 4.21Å; L266-Y426 HydrophobicContact CG-CE1 4.31Å
267	R	54.6	Low	65.7	Low	191 Å²	191	88.3 Å²	88.3	72%	0.721	44%	0.443	S	S	*	.			trans	-102	121.6	165.4	-70.1	-174.6	178.8	166.7	3.5	108.8	N265 D269	N265-R267 VanDerWaalsContact C-N 3.34Å; N265-R267 PolarHBondContact O-N 3.41Å; R267-D269 PolarHBondContact O-N 3.04Å; R267-D269 VanDerWaalsContact O-N 3.11Å
268	L	63.4	Low	67.4	Low	34 Å²	34	87.7 Å²	87.7	18%	0.178	44%	0.439	C	S	.	.			trans	-76.1	95.9	164	-169.1	71.5	0	0	0	107.2	C270 I341 L422 F425 Y426	L268-C270 WeakPolarHBondContact CD2-SG 3.48Å; L268-C270 VanDerWaalsContact CG-SG 3.5Å; L268-C270 PolarHBondContact O-N 3Å; L268-I341 HydrophobicContact CD2-CD1 4.39Å; L268-L422 HydrophobicContact CD2-CD2 4.43Å; L268-F425 HydrophobicContact CD1-CB 4.43Å; L268-Y426 HydrophobicContact CB-CE2 4.48Å; L268-Y426 WeakPolarHBondContact CB-OH 3.5Å; L268-Y426 HydrophobicContact CD1-CD2 4.22Å; L268-Y426 HydrophobicContact CD1-CE2 3.56Å; L268-Y426 HydrophobicContact CD2-CE2 4.36Å; L268-Y426 HydrophobicContact CG-CE2 4.35Å
269	D	66.2	Low	69.1	Low	161 Å²	161	82.1 Å²	82.1	86%	0.861	42%	0.417	S	S	*	.			trans	-73.7	85	174.5	-157.9	-0.2	0	0	0	109.1	R267	R267-D269 PolarHBondContact O-N 3.04Å; R267-D269 VanDerWaalsContact O-N 3.11Å
270	C	71.4	Confident	71	Confident	24 Å²	24	83 Å²	83	16%	0.162	43%	0.428	C	S	.	.			trans	-84	123.9	173.4	-73.6	0	0	0	0	108.9	L268 K272 L274 R275	L268-C270 WeakPolarHBondContact CD2-SG 3.48Å; L268-C270 VanDerWaalsContact CG-SG 3.5Å; L268-C270 PolarHBondContact O-N 3Å; C270-K272 PolarHBondContact O-N 3.25Å; C270-L274 HydrophobicContact CB-CB 4.44Å; C270-L274 HydrophobicContact CB-CD2 4.23Å; C270-L274 HydrophobicContact CB-CG 4.41Å; C270-R275 HydrophobicContact CB-CB 4.3Å
271	D	83	Confident	73.1	Confident	105 Å²	105	83 Å²	83	56%	0.561	43%	0.426	S	S	*	.			trans	-50.9	145	163.9	-175.8	14.4	0	0	0	109.9	K273 L274 R275	D271-K273 PolarHBondContact O-N 3.31Å; D271-L274 PolarHBondContact O-N 2.82Å; D271-R275 PolarHBondContact O-N 2.89Å
272	K	86.1	Confident	75	Confident	180 Å²	180	81.6 Å²	81.6	78%	0.783	42%	0.42	S	S	*	.	H	α-helix	trans	-50.8	-36	-178.7	-69.6	-178.8	-179.5	176.7	0	111.5	C270 R275 S276	C270-K272 PolarHBondContact O-N 3.25Å; K272-R275 PolarHBondContact O-N 3.5Å; K272-S276 WeakPolarHBondContact O-CB 3.37Å; K272-S276 PolarHBondContact O-N 2.93Å
273	K	88.3	Confident	77.2	Confident	167 Å²	167	82.9 Å²	82.9	73%	0.726	42%	0.423	S	S	*	.	H	α-helix	trans	-63	-48.9	175.8	-69	-178.1	179.2	177.6	0	112.6	D271 R275 S276 S277	D271-K273 PolarHBondContact O-N 3.31Å; K273-R275 VanDerWaalsContact C-N 3.34Å; K273-S276 PolarHBondContact O-N 2.86Å; K273-S277 WeakPolarHBondContact O-CB 3.48Å; K273-S277 PolarHBondContact O-N 3.01Å
274	L	86.5	Confident	79.3	Confident	54 Å²	54	82.5 Å²	82.5	28%	0.283	43%	0.428	S	S	.	.	H	α-helix	trans	-64	-42.8	177.9	178.7	60	0	0	0	110.7	C270 D271 S276 S277 I278 L418 L422	C270-L274 HydrophobicContact CB-CB 4.44Å; C270-L274 HydrophobicContact CB-CD2 4.23Å; C270-L274 HydrophobicContact CB-CG 4.41Å; D271-L274 PolarHBondContact O-N 2.82Å; L274-S276 PolarHBondContact O-N 3.33Å; L274-S277 WeakPolarHBondContact O-CB 3.44Å; L274-S277 PolarHBondContact O-N 3.18Å; L274-I278 HydrophobicContact CD1-CD1 3.87Å; L274-I278 HydrophobicContact CD1-CG1 4.22Å; L274-I278 HydrophobicContact CG-CD1 3.88Å; L274-I278 WeakPolarHBondContact O-CG1 3.46Å; L274-I278 PolarHBondContact O-N 3.17Å; L274-L418 HydrophobicContact CD1-CD1 4.16Å; L274-L422 HydrophobicContact CD2-CD2 4.32Å
275	R	86.7	Confident	81.8	Confident	128 Å²	128	78 Å²	78	48%	0.483	40%	0.396	S	S	.	.	H	α-helix	trans	-58.2	-47.5	175.7	172.2	160.2	-173.5	-175.5	4	112.1	C270 D271 K272 K273 V279 I331	C270-R275 HydrophobicContact CB-CB 4.3Å; D271-R275 PolarHBondContact O-N 2.89Å; K272-R275 PolarHBondContact O-N 3.5Å; K273-R275 VanDerWaalsContact C-N 3.34Å; R275-V279 WeakPolarHBondContact O-CG2 3.25Å; R275-V279 PolarHBondContact O-N 3.41Å; R275-V279 VanDerWaalsContact O-N 3.12Å; R275-I331 HydrophobicContact CG-CD1 4.37Å; R275-I331 HydrophobicContact CG-CG2 3.62Å
276	S	89.8	Confident	84.2	Confident	80 Å²	80	73.9 Å²	73.9	56%	0.559	37%	0.373	S	S	*	.	H	α-helix	trans	-64.1	-40.6	176.6	-168.2	0	0	0	0	112	K272 K273 L274 V279 C280	K272-S276 WeakPolarHBondContact O-CB 3.37Å; K272-S276 PolarHBondContact O-N 2.93Å; K273-S276 PolarHBondContact O-N 2.86Å; L274-S276 PolarHBondContact O-N 3.33Å; S276-V279 PolarHBondContact O-N 3.33Å; S276-C280 WeakPolarHBondContact O-CB 3.24Å; S276-C280 PolarHBondContact O-N 3.35Å
277	S	90.8	Very high	86.2	Confident	45 Å²	45	75.7 Å²	75.7	32%	0.315	38%	0.383	S	S	.	.	H	α-helix	trans	-60.9	-46.6	178	-179	0	0	0	0	111.8	K273 L274 V279 C280 F281	K273-S277 WeakPolarHBondContact O-CB 3.48Å; K273-S277 PolarHBondContact O-N 3.01Å; L274-S277 WeakPolarHBondContact O-CB 3.44Å; L274-S277 PolarHBondContact O-N 3.18Å; S277-V279 PolarHBondContact O-N 2.79Å; S277-C280 PolarHBondContact O-N 2.95Å; S277-F281 VanDerWaalsContact O-CB 3.25Å; S277-F281 WeakPolarHBondContact O-CB 3.2Å; S277-F281 PolarHBondContact O-N 3.32Å
278	I	91	Very high	88	Confident	0 Å²	0	67.4 Å²	67.4	0%	0	35%	0.354	C	S	.	.	H	α-helix	trans	-68	-36.6	179.5	-66.5	162.9	0	0	0	111.7	L274 F281 G282 I331 L418 F419 L422	L274-I278 HydrophobicContact CD1-CD1 3.87Å; L274-I278 HydrophobicContact CD1-CG1 4.22Å; L274-I278 HydrophobicContact CG-CD1 3.88Å; L274-I278 WeakPolarHBondContact O-CG1 3.46Å; L274-I278 PolarHBondContact O-N 3.17Å; I278-F281 PolarHBondContact O-N 2.85Å; I278-G282 PolarHBondContact O-N 3.46Å; I278-I331 HydrophobicContact CB-CD1 3.27Å; I278-I331 HydrophobicContact CB-CG1 4.42Å; I278-I331 HydrophobicContact CD1-CD1 3.69Å; I278-I331 HydrophobicContact CD1-CG1 4.4Å; I278-I331 HydrophobicContact CG1-CD1 4.05Å; I278-I331 HydrophobicContact CG2-CD1 3.24Å; I278-I331 HydrophobicContact CG2-CG1 3.95Å; I278-L418 HydrophobicContact CG1-CD2 4.13Å; I278-F419 HydrophobicContact CG2-CZ 3.93Å; I278-L422 HydrophobicContact CD1-CD1 3.93Å
279	V	92.6	Very high	89.3	Confident	34 Å²	34	65.8 Å²	65.8	21%	0.206	35%	0.346	C	S	.	.	H	α-helix	trans	-65.2	-45.7	174.3	171.5	0	0	0	0	110.6	R275 S276 S277 G282 L283	R275-V279 WeakPolarHBondContact O-CG2 3.25Å; R275-V279 PolarHBondContact O-N 3.41Å; R275-V279 VanDerWaalsContact O-N 3.12Å; S276-V279 PolarHBondContact O-N 3.33Å; S277-V279 PolarHBondContact O-N 2.79Å; V279-G282 PolarHBondContact O-N 3.19Å; V279-L283 HydrophobicContact CG1-CD1 4.05Å; V279-L283 HydrophobicContact CG1-CG 4.48Å; V279-L283 WeakPolarHBondContact O-CB 3.36Å; V279-L283 WeakPolarHBondContact O-CG 3.25Å; V279-L283 PolarHBondContact O-N 3.25Å
280	C	94	Very high	90.5	Very high	76 Å²	76	60 Å²	60	51%	0.514	32%	0.321	S	S	.	.	H	α-helix	trans	-58.7	-48.8	175	-173.8	0	0	0	0	110.8	S276 S277 G282 L283 S284	S276-C280 WeakPolarHBondContact O-CB 3.24Å; S276-C280 PolarHBondContact O-N 3.35Å; S277-C280 PolarHBondContact O-N 2.95Å; C280-G282 PolarHBondContact O-N 3.41Å; C280-L283 PolarHBondContact O-N 3.03Å; C280-S284 PolarHBondContact O-N 3.48Å; C280-S284 PolarHBondContact O-OG 3.43Å
281	F	94.9	Very high	91.5	Very high	6 Å²	6	62.6 Å²	62.6	3%	0.026	33%	0.333	C	S	.	.	H	α-helix	trans	-56	-49.3	175.9	179.9	-97.5	0	0	0	112.2	S277 I278 L283 S284 L285 L348 M411 Y414 G415 F419	S277-F281 VanDerWaalsContact O-CB 3.25Å; S277-F281 WeakPolarHBondContact O-CB 3.2Å; S277-F281 PolarHBondContact O-N 3.32Å; I278-F281 PolarHBondContact O-N 2.85Å; F281-L283 PolarHBondContact O-N 3.12Å; F281-S284 WeakPolarHBondContact O-CB 3.03Å; F281-S284 PolarHBondContact O-N 2.96Å; F281-L285 HydrophobicContact CD1-CD1 3.95Å; F281-L285 HydrophobicContact CD1-CG 4.46Å; F281-L285 HydrophobicContact CE1-CD1 3.4Å; F281-L285 VanDerWaalsContact CE1-CD1 3.4Å; F281-L285 HydrophobicContact CE1-CG 4.09Å; F281-L285 HydrophobicContact CZ-CD1 3.84Å; F281-L285 HydrophobicContact CZ-CD2 4.17Å; F281-L285 HydrophobicContact CZ-CG 4.17Å; F281-L285 WeakPolarHBondContact O-CG 3.27Å; F281-L285 PolarHBondContact O-N 2.87Å; F281-L348 HydrophobicContact CE1-CD1 4.07Å; F281-L348 HydrophobicContact CE1-CD2 4.3Å; F281-L348 HydrophobicContact CZ-CD1 4.11Å; F281-L348 HydrophobicContact CZ-CD2 3.98Å; F281-M411 HydrophobicContact CD2-CE 3.25Å; F281-M411 HydrophobicContact CD2-SD 4.11Å; F281-M411 HydrophobicContact CE2-CB 4.11Å; F281-M411 HydrophobicContact CE2-CE 3.52Å; F281-M411 VanDerWaalsContact CE2-O 3.28Å; F281-M411 WeakPolarHBondContact CE2-O 3.05Å; F281-M411 HydrophobicContact CE2-SD 4.06Å; F281-M411 HydrophobicContact CG-CE 4.22Å; F281-M411 WeakPolarHBondContact CZ-O 3.24Å; F281-Y414 HydrophobicContact CD2-CD1 4.06Å; F281-Y414 HydrophobicContact CD2-CE1 4.3Å; F281-Y414 HydrophobicContact CE2-CD1 4.01Å; F281-G415 VanDerWaalsContact CZ-CA 3.49Å; F281-F419 AromaticContact CD1-CE2 3.87Å; F281-F419 HydrophobicContact CD1-CE2 3.87Å; F281-F419 HydrophobicContact CE1-CD2 4.4Å; F281-F419 AromaticContact CE1-CE2 3.74Å; F281-F419 HydrophobicContact CE1-CE2 3.74Å
282	G	93.7	Very high	91.7	Very high	0 Å²	0	57.9 Å²	57.9	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-63.4	-38.8	178.7	0	0	0	0	0	113.3	I278 V279 C280 L285 I286 G324	I278-G282 PolarHBondContact O-N 3.46Å; V279-G282 PolarHBondContact O-N 3.19Å; C280-G282 PolarHBondContact O-N 3.41Å; G282-L285 PolarHBondContact O-N 2.87Å; G282-I286 WeakPolarHBondContact O-CG1 3.17Å; G282-I286 PolarHBondContact O-N 3.47Å; G282-I286 VanDerWaalsContact O-N 3.13Å; G282-G324 VanDerWaalsContact O-CA 3.32Å; G282-G324 WeakPolarHBondContact O-CA 3.33Å
283	L	95.9	Very high	91.6	Very high	99 Å²	99	50.5 Å²	50.5	52%	0.518	28%	0.278	S	S	.	.	H	α-helix	trans	-66.3	-41.3	173.8	-72.6	172.6	0	0	0	111.7	V279 C280 F281 L285 I286 L287 I328	V279-L283 HydrophobicContact CG1-CD1 4.05Å; V279-L283 HydrophobicContact CG1-CG 4.48Å; V279-L283 WeakPolarHBondContact O-CB 3.36Å; V279-L283 WeakPolarHBondContact O-CG 3.25Å; V279-L283 PolarHBondContact O-N 3.25Å; C280-L283 PolarHBondContact O-N 3.03Å; F281-L283 PolarHBondContact O-N 3.12Å; L283-L285 VanDerWaalsContact C-N 3.32Å; L283-L285 PolarHBondContact O-N 3.19Å; L283-I286 PolarHBondContact O-N 2.8Å; L283-L287 WeakPolarHBondContact O-CB 3.44Å; L283-L287 PolarHBondContact O-N 3.48Å; L283-I328 HydrophobicContact CD2-CD1 3.96Å; L283-I328 HydrophobicContact CG-CD1 4.09Å
284	S	95.4	Very high	91.5	Very high	43 Å²	43	46.2 Å²	46.2	30%	0.301	27%	0.266	S	S	.	.	H	α-helix	trans	-60.3	-41.4	175.5	-61.4	0	0	0	0	111.7	C280 F281 L287 S288	C280-S284 PolarHBondContact O-N 3.48Å; C280-S284 PolarHBondContact O-OG 3.43Å; F281-S284 WeakPolarHBondContact O-CB 3.03Å; F281-S284 PolarHBondContact O-N 2.96Å; S284-L287 PolarHBondContact O-N 3.4Å; S284-S288 WeakPolarHBondContact O-CB 3.3Å; S284-S288 PolarHBondContact O-N 3.41Å; S284-S288 PolarHBondContact O-OG 2.8Å; S284-S288 VanDerWaalsContact O-OG 3.04Å
285	L	95.2	Very high	91.2	Very high	1 Å²	1	44.7 Å²	44.7	1%	0.005	26%	0.258	C	S	.	.	H	α-helix	trans	-63.4	-45.6	175.4	-67	174.9	0	0	0	112.4	F281 G282 L283 L287 S288 G289 L320 A323 L348	F281-L285 HydrophobicContact CD1-CD1 3.95Å; F281-L285 HydrophobicContact CD1-CG 4.46Å; F281-L285 HydrophobicContact CE1-CD1 3.4Å; F281-L285 VanDerWaalsContact CE1-CD1 3.4Å; F281-L285 HydrophobicContact CE1-CG 4.09Å; F281-L285 HydrophobicContact CZ-CD1 3.84Å; F281-L285 HydrophobicContact CZ-CD2 4.17Å; F281-L285 HydrophobicContact CZ-CG 4.17Å; F281-L285 WeakPolarHBondContact O-CG 3.27Å; F281-L285 PolarHBondContact O-N 2.87Å; G282-L285 PolarHBondContact O-N 2.87Å; L283-L285 VanDerWaalsContact C-N 3.32Å; L283-L285 PolarHBondContact O-N 3.19Å; L285-L287 VanDerWaalsContact C-N 3.32Å; L285-L287 PolarHBondContact O-N 3.17Å; L285-S288 PolarHBondContact O-N 3.46Å; L285-G289 PolarHBondContact O-N 2.84Å; L285-L320 HydrophobicContact CD2-CD2 3.83Å; L285-A323 HydrophobicContact CD1-CB 4.09Å; L285-L348 HydrophobicContact CD1-CD2 3.9Å; L285-L348 HydrophobicContact CD2-CD2 4.09Å
286	I	94.9	Very high	90.7	Very high	53 Å²	53	38.8 Å²	38.8	27%	0.272	24%	0.236	S	C	.	.	H	α-helix	trans	-61	-45.4	177.2	-68.2	166.1	0	0	0	110.1	G282 L283 G289 A290 I328	G282-I286 WeakPolarHBondContact O-CG1 3.17Å; G282-I286 PolarHBondContact O-N 3.47Å; G282-I286 VanDerWaalsContact O-N 3.13Å; L283-I286 PolarHBondContact O-N 2.8Å; I286-G289 PolarHBondContact O-N 2.86Å; I286-A290 WeakPolarHBondContact O-CB 3.43Å; I286-A290 PolarHBondContact O-N 3.28Å; I286-I328 HydrophobicContact CD1-CD1 3.85Å
287	L	95.2	Very high	90.1	Very high	108 Å²	108	38.6 Å²	38.6	57%	0.565	23%	0.228	S	C	*	.	H	α-helix	trans	-61.9	-46.2	178.3	-178.5	61.7	0	0	0	111.1	L283 S284 L285 G289 A290 L291	L283-L287 WeakPolarHBondContact O-CB 3.44Å; L283-L287 PolarHBondContact O-N 3.48Å; S284-L287 PolarHBondContact O-N 3.4Å; L285-L287 VanDerWaalsContact C-N 3.32Å; L285-L287 PolarHBondContact O-N 3.17Å; L287-G289 PolarHBondContact O-N 2.54Å; L287-A290 PolarHBondContact O-N 3.5Å; L287-L291 HydrophobicContact CD1-CG 4.45Å; L287-L291 HydrophobicContact CG-CD1 4.21Å; L287-L291 WeakPolarHBondContact O-CB 3.07Å; L287-L291 VanDerWaalsContact O-CG 3.3Å; L287-L291 WeakPolarHBondContact O-CG 3.09Å; L287-L291 PolarHBondContact O-N 3.47Å
288	S	93	Very high	89.4	Confident	17 Å²	17	39.9 Å²	39.9	12%	0.119	23%	0.233	C	C	.	.	H	α-helix	trans	-60.1	-45.2	175.7	-66.6	0	0	0	0	112.1	S284 L285 A290 L291 F292	S284-S288 WeakPolarHBondContact O-CB 3.3Å; S284-S288 PolarHBondContact O-N 3.41Å; S284-S288 PolarHBondContact O-OG 2.8Å; S284-S288 VanDerWaalsContact O-OG 3.04Å; L285-S288 PolarHBondContact O-N 3.46Å; S288-A290 VanDerWaalsContact C-N 3.34Å; S288-A290 PolarHBondContact O-N 3.05Å; S288-L291 PolarHBondContact O-N 2.96Å; S288-F292 WeakPolarHBondContact O-CD2 3.18Å; S288-F292 PolarHBondContact O-N 2.77Å
289	G	91.1	Very high	88.4	Confident	0 Å²	0	40.2 Å²	40.2	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-63	-38.4	176.3	0	0	0	0	0	113.2	L285 I286 L287 S293	L285-G289 PolarHBondContact O-N 2.84Å; I286-G289 PolarHBondContact O-N 2.86Å; L287-G289 PolarHBondContact O-N 2.54Å; G289-S293 PolarHBondContact O-N 2.86Å; G289-S293 PolarHBondContact O-OG 3.29Å
290	A	91.6	Very high	87.1	Confident	41 Å²	41	40.2 Å²	40.2	34%	0.339	24%	0.235	S	C	.	.	H	α-helix	trans	-67.1	-39.3	174.3	0	0	0	0	0	112.3	I286 L287 S288 S293 T294	I286-A290 WeakPolarHBondContact O-CB 3.43Å; I286-A290 PolarHBondContact O-N 3.28Å; L287-A290 PolarHBondContact O-N 3.5Å; S288-A290 VanDerWaalsContact C-N 3.34Å; S288-A290 PolarHBondContact O-N 3.05Å; A290-S293 PolarHBondContact O-N 3.49Å; A290-T294 WeakPolarHBondContact O-CB 3.5Å; A290-T294 PolarHBondContact O-N 3.01Å; A290-T294 PolarHBondContact O-OG1 3.04Å
291	L	91.3	Very high	85.9	Confident	78 Å²	78	44.2 Å²	44.2	41%	0.408	25%	0.246	S	C	.	.	H	α-helix	trans	-63.6	-47.1	175.1	-73.7	171.6	0	0	0	111.4	L287 S288 S293 T294 I295 L404	L287-L291 HydrophobicContact CD1-CG 4.45Å; L287-L291 HydrophobicContact CG-CD1 4.21Å; L287-L291 WeakPolarHBondContact O-CB 3.07Å; L287-L291 VanDerWaalsContact O-CG 3.3Å; L287-L291 WeakPolarHBondContact O-CG 3.09Å; L287-L291 PolarHBondContact O-N 3.47Å; S288-L291 PolarHBondContact O-N 2.96Å; L291-S293 VanDerWaalsContact C-N 3.34Å; L291-S293 PolarHBondContact O-N 3.48Å; L291-T294 WeakPolarHBondContact O-CB 3.44Å; L291-T294 PolarHBondContact O-N 3.35Å; L291-T294 VanDerWaalsContact O-N 3.12Å; L291-I295 VanDerWaalsContact O-CG1 3.29Å; L291-I295 WeakPolarHBondContact O-CG1 2.85Å; L291-I295 PolarHBondContact O-N 3.28Å; L291-L404 HydrophobicContact CB-CD2 3.73Å; L291-L404 HydrophobicContact CD1-CD1 4.3Å; L291-L404 HydrophobicContact CD1-CD2 4.45Å
292	F	88	Confident	84.4	Confident	6 Å²	6	46.5 Å²	46.5	3%	0.026	27%	0.266	C	S	.	.	H	α-helix	trans	-58.4	-45.3	173.8	-81.7	-65.6	0	0	0	112.1	S288 T294 I295 D296 L316 P317 L320 E401 L404 A405 V408	S288-F292 WeakPolarHBondContact O-CD2 3.18Å; S288-F292 PolarHBondContact O-N 2.77Å; F292-T294 PolarHBondContact O-N 3.05Å; F292-I295 PolarHBondContact O-N 3.31Å; F292-D296 PolarHBondContact O-N 3.28Å; F292-L316 HydrophobicContact CD1-CD2 4.4Å; F292-L316 HydrophobicContact CD2-CD2 3.67Å; F292-L316 HydrophobicContact CD2-CG 4.22Å; F292-L316 HydrophobicContact CE1-CD2 4.07Å; F292-L316 HydrophobicContact CE2-CD2 3.28Å; F292-L316 HydrophobicContact CE2-CG 4.22Å; F292-L316 HydrophobicContact CG-CD2 4.23Å; F292-L316 HydrophobicContact CZ-CD2 3.51Å; F292-P317 HydrophobicContact CB-CG 3.77Å; F292-L320 HydrophobicContact CD2-CD1 3.99Å; F292-L320 HydrophobicContact CE2-CD1 4.22Å; F292-E401 HydrophobicContact CD1-CG 4.06Å; F292-E401 HydrophobicContact CE1-CG 3.71Å; F292-L404 HydrophobicContact CD1-CD2 4.08Å; F292-L404 HydrophobicContact CD2-CD2 3.66Å; F292-L404 HydrophobicContact CD2-CG 4.17Å; F292-L404 HydrophobicContact CE1-CB 4.39Å; F292-L404 HydrophobicContact CE1-CD2 3.97Å; F292-L404 HydrophobicContact CE1-CG 4.27Å; F292-L404 HydrophobicContact CE2-CB 4.36Å; F292-L404 HydrophobicContact CE2-CD2 3.53Å; F292-L404 HydrophobicContact CE2-CG 3.53Å; F292-L404 HydrophobicContact CG-CD2 3.92Å; F292-L404 HydrophobicContact CZ-CB 3.91Å; F292-L404 HydrophobicContact CZ-CD2 3.69Å; F292-L404 HydrophobicContact CZ-CG 3.58Å; F292-A405 HydrophobicContact CZ-CB 4.03Å; F292-V408 HydrophobicContact CE2-CG2 3.91Å
293	S	83.8	Confident	82.6	Confident	25 Å²	25	49.2 Å²	49.2	18%	0.175	30%	0.295	C	S	.	.	H	α-helix	trans	-59.5	-38.6	175.8	-52.7	0	0	0	0	111.9	Y219 G289 A290 L291 D296 I297 P317	Y219-S293 PolarHBondContact OH-O 3.37Å; G289-S293 PolarHBondContact O-N 2.86Å; G289-S293 PolarHBondContact O-OG 3.29Å; A290-S293 PolarHBondContact O-N 3.49Å; L291-S293 VanDerWaalsContact C-N 3.34Å; L291-S293 PolarHBondContact O-N 3.48Å; S293-D296 WeakPolarHBondContact O-CB 3.4Å; S293-I297 WeakPolarHBondContact O-CD1 3.47Å; S293-I297 VanDerWaalsContact O-CG1 3.23Å; S293-I297 WeakPolarHBondContact O-CG1 3.42Å; S293-I297 PolarHBondContact O-N 3.38Å; S293-P317 VanDerWaalsContact OG-CB 3.29Å; S293-P317 WeakPolarHBondContact OG-CB 2.93Å
294	T	85.4	Confident	80.7	Confident	77 Å²	77	45 Å²	45	47%	0.472	27%	0.273	S	S	.	.	H	α-helix	trans	-68.6	-42.7	177.9	-54.6	0	0	0	0	111	A290 L291 F292 D296 I297 V298	A290-T294 WeakPolarHBondContact O-CB 3.5Å; A290-T294 PolarHBondContact O-N 3.01Å; A290-T294 PolarHBondContact O-OG1 3.04Å; L291-T294 WeakPolarHBondContact O-CB 3.44Å; L291-T294 PolarHBondContact O-N 3.35Å; L291-T294 VanDerWaalsContact O-N 3.12Å; F292-T294 PolarHBondContact O-N 3.05Å; T294-D296 VanDerWaalsContact C-N 3.35Å; T294-I297 PolarHBondContact O-N 3.38Å; T294-V298 HydrophobicContact CG2-CG2 4.37Å; T294-V298 WeakPolarHBondContact O-CB 3.49Å; T294-V298 VanDerWaalsContact O-CG2 3.26Å; T294-V298 WeakPolarHBondContact O-CG2 3.37Å; T294-V298 PolarHBondContact O-N 2.89Å
295	I	81.2	Confident	78.4	Confident	21 Å²	21	44.1 Å²	44.1	11%	0.108	26%	0.264	C	S	.	.	H	α-helix	trans	-60.6	-45.1	175.7	-68.6	166.8	0	0	0	110.2	L291 F292 I297 V298 N299 L397 E401 L404	L291-I295 VanDerWaalsContact O-CG1 3.29Å; L291-I295 WeakPolarHBondContact O-CG1 2.85Å; L291-I295 PolarHBondContact O-N 3.28Å; F292-I295 PolarHBondContact O-N 3.31Å; I295-I297 PolarHBondContact O-N 2.85Å; I295-V298 PolarHBondContact O-N 2.98Å; I295-N299 WeakPolarHBondContact CG2-ND2 3.31Å; I295-N299 VanDerWaalsContact O-CB 3.28Å; I295-N299 WeakPolarHBondContact O-CB 3.47Å; I295-N299 PolarHBondContact O-N 2.73Å; I295-N299 PolarHBondContact O-ND2 3.1Å; I295-L397 HydrophobicContact CB-CD1 4.49Å; I295-L397 HydrophobicContact CG1-CD1 4.03Å; I295-L397 HydrophobicContact CG2-CD1 3.99Å; I295-L397 HydrophobicContact CG2-CD2 4.3Å; I295-L397 HydrophobicContact CG2-CG 3.96Å; I295-E401 HydrophobicContact CD1-CB 4.41Å; I295-E401 HydrophobicContact CG2-CB 4.41Å; I295-E401 HydrophobicContact CG2-CG 4.28Å; I295-L404 HydrophobicContact CD1-CD2 4.29Å
296	D	76.9	Confident	76.4	Confident	5 Å²	5	45.1 Å²	45.1	3%	0.027	27%	0.268	C	S	.	.	H	α-helix	trans	-55.1	-52.2	174.5	-78.2	-32.7	0	0	0	111.4	Y219 F292 S293 T294 V298 N299 V300 H314	Y219-D296 HydrophobicContact CE1-CB 4.33Å; Y219-D296 WeakPolarHBondContact OH-CB 3.16Å; F292-D296 PolarHBondContact O-N 3.28Å; S293-D296 WeakPolarHBondContact O-CB 3.4Å; T294-D296 VanDerWaalsContact C-N 3.35Å; D296-V298 PolarHBondContact O-N 3.28Å; D296-N299 PolarHBondContact O-N 2.8Å; D296-V300 WeakPolarHBondContact O-CG2 3.08Å; D296-V300 PolarHBondContact O-N 3.27Å; D296-V300 VanDerWaalsContact O-N 3.14Å; D296-H314 IonicContact OD1-CE1 2.8Å; D296-H314 IonicContact OD1-CG 3.95Å; D296-H314 IonicContact OD1-ND1 3.77Å; D296-H314 PolarHBondContact OD1-ND1 3.28Å; D296-H314 IonicContact OD2-ND1 3.54Å
297	I	76.6	Confident	74.2	Confident	75 Å²	75	43.6 Å²	43.6	39%	0.385	26%	0.26	S	S	.	.	H	α-helix	trans	-60.2	-46.3	179.5	-67.8	165.5	0	0	0	110.6	S293 T294 I295 V300 H301	S293-I297 WeakPolarHBondContact O-CD1 3.47Å; S293-I297 VanDerWaalsContact O-CG1 3.23Å; S293-I297 WeakPolarHBondContact O-CG1 3.42Å; S293-I297 PolarHBondContact O-N 3.38Å; T294-I297 PolarHBondContact O-N 3.38Å; I295-I297 PolarHBondContact O-N 2.85Å; I297-V300 PolarHBondContact O-N 3.23Å; I297-H301 PolarHBondContact O-N 3.01Å; I297-H301 VanDerWaalsContact O-N 3.08Å; I297-H301 PolarHBondContact O-ND1 3.33Å
298	V	76.2	Confident	71.9	Confident	72 Å²	72	42.7 Å²	42.7	44%	0.436	26%	0.259	S	S	.	.	H	α-helix	trans	-63.6	-45.3	-179.9	169.7	0	0	0	0	111.3	T294 I295 D296 V300 H301 A302 L397	T294-V298 HydrophobicContact CG2-CG2 4.37Å; T294-V298 WeakPolarHBondContact O-CB 3.49Å; T294-V298 VanDerWaalsContact O-CG2 3.26Å; T294-V298 WeakPolarHBondContact O-CG2 3.37Å; T294-V298 PolarHBondContact O-N 2.89Å; I295-V298 PolarHBondContact O-N 2.98Å; D296-V298 PolarHBondContact O-N 3.28Å; V298-V300 PolarHBondContact O-N 2.8Å; V298-H301 PolarHBondContact O-N 2.95Å; V298-A302 VanDerWaalsContact O-CB 3.29Å; V298-A302 WeakPolarHBondContact O-CB 3.34Å; V298-A302 PolarHBondContact O-N 2.94Å; V298-L397 HydrophobicContact CG1-CD2 4.02Å
299	N	70	Confident	69.7	Low	7 Å²	7	42.7 Å²	42.7	4%	0.037	26%	0.256	C	S	.	.	H	α-helix	trans	-53.9	-40.4	177	-91.9	-36.9	0	0	0	111.2	I295 D296 A302 G303 T304 L397	I295-N299 WeakPolarHBondContact CG2-ND2 3.31Å; I295-N299 VanDerWaalsContact O-CB 3.28Å; I295-N299 WeakPolarHBondContact O-CB 3.47Å; I295-N299 PolarHBondContact O-N 2.73Å; I295-N299 PolarHBondContact O-ND2 3.1Å; D296-N299 PolarHBondContact O-N 2.8Å; N299-A302 CarbonylContact O-C 3.59Å; N299-A302 PolarHBondContact O-N 3.12Å; N299-G303 PolarHBondContact O-N 3.21Å; N299-G303 VanDerWaalsContact O-N 3.09Å; N299-T304 VanDerWaalsContact CA-OG1 3.27Å; N299-T304 WeakPolarHBondContact CA-OG1 3.35Å; N299-T304 WeakPolarHBondContact CB-OG1 3.35Å; N299-T304 VanDerWaalsContact CG-OG1 3.25Å; N299-T304 PolarHBondContact O-N 3.22Å; N299-T304 PolarHBondContact O-OG1 2.8Å; N299-T304 PolarHBondContact OD1-OG1 2.93Å; N299-L397 WeakPolarHBondContact OD1-CD2 3.36Å
300	V	64.4	Low	67.9	Low	34 Å²	34	43.1 Å²	43.1	21%	0.206	26%	0.258	C	S	.	.	H	α-helix	trans	-74.3	-44.1	-176.5	169.4	0	0	0	0	112.2	I223 D296 I297 V298 A302 G303 H307	I223-V300 HydrophobicContact CB-CG1 4.39Å; I223-V300 HydrophobicContact CB-CG2 4.38Å; I223-V300 HydrophobicContact CG2-CB 3.5Å; I223-V300 VanDerWaalsContact CG2-CB 3.5Å; I223-V300 HydrophobicContact CG2-CG1 3.39Å; I223-V300 HydrophobicContact CG2-CG2 2.91Å; I223-V300 WeakPolarHBondContact O-CG1 3.01Å; D296-V300 WeakPolarHBondContact O-CG2 3.08Å; D296-V300 PolarHBondContact O-N 3.27Å; D296-V300 VanDerWaalsContact O-N 3.14Å; I297-V300 PolarHBondContact O-N 3.23Å; V298-V300 PolarHBondContact O-N 2.8Å; V300-A302 PolarHBondContact O-N 3.05Å; V300-G303 WeakPolarHBondContact O-CA 3.27Å; V300-G303 PolarHBondContact O-N 3.22Å; V300-H307 WeakPolarHBondContact CG2-CD2 3.43Å; V300-H307 WeakPolarHBondContact CG2-NE2 3.42Å
301	H	68.6	Low	65.7	Low	160 Å²	160	43.3 Å²	43.3	74%	0.741	26%	0.256	S	S	*	.	H	α-helix	trans	-62.9	-34.2	175	-74	80.2	0	0	0	111.4	I297 V298 G303	I297-H301 PolarHBondContact O-N 3.01Å; I297-H301 VanDerWaalsContact O-N 3.08Å; I297-H301 PolarHBondContact O-ND1 3.33Å; V298-H301 PolarHBondContact O-N 2.95Å; H301-G303 PolarHBondContact O-N 3.09Å
302	A	64.3	Low	63.6	Low	54 Å²	54	40.5 Å²	40.5	45%	0.446	24%	0.243	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.1	-8.5	174.1	0	0	0	0	0	113.2	V298 N299 V300 T304	V298-A302 VanDerWaalsContact O-CB 3.29Å; V298-A302 WeakPolarHBondContact O-CB 3.34Å; V298-A302 PolarHBondContact O-N 2.94Å; N299-A302 CarbonylContact O-C 3.59Å; N299-A302 PolarHBondContact O-N 3.12Å; V300-A302 PolarHBondContact O-N 3.05Å; A302-T304 HydrophobicContact CB-CG2 3.78Å; A302-T304 PolarHBondContact O-N 3.18Å
303	G	55.5	Low	61.9	Low	58 Å²	58	40.9 Å²	40.9	60%	0.598	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	60.5	28	-174.9	0	0	0	0	0	112.5	N299 V300 H301 F305	N299-G303 PolarHBondContact O-N 3.21Å; N299-G303 VanDerWaalsContact O-N 3.09Å; V300-G303 WeakPolarHBondContact O-CA 3.27Å; V300-G303 PolarHBondContact O-N 3.22Å; H301-G303 PolarHBondContact O-N 3.09Å; G303-F305 PolarHBondContact O-N 3.34Å
304	T	56.7	Low	60.8	Low	10 Å²	10	40 Å²	40	6%	0.061	24%	0.238	C	C	.	.			trans	-65.1	132.4	-177.3	56.9	0	0	0	0	109.3	N299 A302 H306 V390	N299-T304 VanDerWaalsContact CA-OG1 3.27Å; N299-T304 WeakPolarHBondContact CA-OG1 3.35Å; N299-T304 WeakPolarHBondContact CB-OG1 3.35Å; N299-T304 VanDerWaalsContact CG-OG1 3.25Å; N299-T304 PolarHBondContact O-N 3.22Å; N299-T304 PolarHBondContact O-OG1 2.8Å; N299-T304 PolarHBondContact OD1-OG1 2.93Å; A302-T304 HydrophobicContact CB-CG2 3.78Å; A302-T304 PolarHBondContact O-N 3.18Å; T304-H306 PolarHBondContact O-N 2.85Å; T304-V390 HydrophobicContact CG2-CG1 4.34Å
305	F	47.3	Very low	60.2	Low	25 Å²	25	38.4 Å²	38.4	11%	0.11	22%	0.224	C	C	.	.	G	3₁₀ helix	trans	-58.3	-20.5	-168.4	166.6	-114.2	0	0	0	114.6	G303 H307 F309 L375 F379 F380	G303-F305 PolarHBondContact O-N 3.34Å; F305-H307 VanDerWaalsContact C-N 3.26Å; F305-H307 PolarHBondContact O-N 2.98Å; F305-F309 AromaticContact CD1-CE2 3.91Å; F305-F309 HydrophobicContact CD1-CE2 3.91Å; F305-F309 AromaticContact CD2-CE2 3.96Å; F305-F309 HydrophobicContact CD2-CE2 3.96Å; F305-F309 HydrophobicContact CD2-CZ 4.34Å; F305-F309 HydrophobicContact CE1-CD2 4.16Å; F305-F309 AromaticContact CE1-CE2 3.27Å; F305-F309 HydrophobicContact CE1-CE2 3.27Å; F305-F309 AromaticContact CE1-CZ 3.91Å; F305-F309 HydrophobicContact CE1-CZ 3.91Å; F305-F309 AromaticContact CE2-CE2 3.41Å; F305-F309 HydrophobicContact CE2-CE2 3.41Å; F305-F309 VanDerWaalsContact CE2-CE2 3.41Å; F305-F309 AromaticContact CE2-CZ 3.44Å; F305-F309 HydrophobicContact CE2-CZ 3.44Å; F305-F309 VanDerWaalsContact CE2-CZ 3.44Å; F305-F309 HydrophobicContact CG-CE2 4.2Å; F305-F309 HydrophobicContact CZ-CD2 4.19Å; F305-F309 HydrophobicContact CZ-CE1 4.45Å; F305-F309 AromaticContact CZ-CE2 2.97Å; F305-F309 HydrophobicContact CZ-CE2 2.97Å; F305-F309 AromaticContact CZ-CZ 3.12Å; F305-F309 HydrophobicContact CZ-CZ 3.12Å; F305-F309 WeakPolarHBondContact O-CE2 3.34Å; F305-L375 HydrophobicContact CD1-CD2 3.45Å; F305-L375 VanDerWaalsContact CD1-CD2 3.45Å; F305-L375 HydrophobicContact CD1-CG 3.84Å; F305-L375 HydrophobicContact CE1-CD1 4.08Å; F305-L375 HydrophobicContact CE1-CD2 3.59Å; F305-L375 HydrophobicContact CE1-CG 3.55Å; F305-F379 HydrophobicContact CD2-CB 4.49Å; F305-F379 HydrophobicContact CE1-CB 4.12Å; F305-F379 HydrophobicContact CE1-CD1 4.39Å; F305-F379 AromaticContact CE1-CD2 3.53Å; F305-F379 HydrophobicContact CE1-CD2 3.53Å; F305-F379 HydrophobicContact CE1-CE1 4.46Å; F305-F379 AromaticContact CE1-CE2 3.76Å; F305-F379 HydrophobicContact CE1-CE2 3.76Å; F305-F379 AromaticContact CE1-CG 3.88Å; F305-F379 HydrophobicContact CE1-CG 3.88Å; F305-F379 HydrophobicContact CE1-CZ 4.2Å; F305-F379 HydrophobicContact CE2-CB 3.27Å; F305-F379 HydrophobicContact CE2-CD1 4.1Å; F305-F379 HydrophobicContact CE2-CD2 4.26Å; F305-F379 AromaticContact CE2-CG 3.75Å; F305-F379 HydrophobicContact CE2-CG 3.75Å; F305-F379 HydrophobicContact CZ-CB 3.07Å; F305-F379 AromaticContact CZ-CD1 3.41Å; F305-F379 HydrophobicContact CZ-CD1 3.41Å; F305-F379 VanDerWaalsContact CZ-CD1 3.41Å; F305-F379 AromaticContact CZ-CD2 3.18Å; F305-F379 HydrophobicContact CZ-CD2 3.18Å; F305-F379 AromaticContact CZ-CE1 3.79Å; F305-F379 HydrophobicContact CZ-CE1 3.79Å; F305-F379 AromaticContact CZ-CE2 3.7Å; F305-F379 HydrophobicContact CZ-CE2 3.7Å; F305-F379 AromaticContact CZ-CG 3.01Å; F305-F379 HydrophobicContact CZ-CG 3.01Å; F305-F379 AromaticContact CZ-CZ 3.96Å; F305-F379 HydrophobicContact CZ-CZ 3.96Å; F305-F380 HydrophobicContact CB-CE2 4.42Å; F305-F380 AromaticContact CD2-CD2 3.76Å; F305-F380 HydrophobicContact CD2-CD2 3.76Å; F305-F380 AromaticContact CD2-CE2 3.09Å; F305-F380 HydrophobicContact CD2-CE2 3.09Å; F305-F380 AromaticContact CD2-CZ 3.67Å; F305-F380 HydrophobicContact CD2-CZ 3.67Å; F305-F380 AromaticContact CE2-CD2 4Å; F305-F380 HydrophobicContact CE2-CD2 4Å; F305-F380 AromaticContact CE2-CE2 3.59Å; F305-F380 HydrophobicContact CE2-CE2 3.59Å; F305-F380 AromaticContact CE2-CZ 3.95Å; F305-F380 HydrophobicContact CE2-CZ 3.95Å; F305-F380 HydrophobicContact CG-CE2 4.08Å
306	H	52.7	Low	60.2	Low	22 Å²	22	37.7 Å²	37.7	10%	0.102	22%	0.221	C	C	.	.	G	3₁₀ helix	trans	-74.1	-10	-171.7	-66.2	-80.3	0	0	0	115.2	T304 V308 F309 Y310 F371 L375 H398	T304-H306 PolarHBondContact O-N 2.85Å; H306-V308 PolarHBondContact O-N 3.46Å; H306-F309 PolarHBondContact O-N 3.27Å; H306-F309 VanDerWaalsContact O-N 3.11Å; H306-Y310 HydrophobicContact CB-CD2 4.49Å; H306-Y310 HydrophobicContact CB-CE2 4.2Å; H306-Y310 WeakPolarHBondContact O-CD2 3.44Å; H306-F371 AromaticContact CE1-CE1 3.92Å; H306-L375 WeakPolarHBondContact CE1-CD2 3.43Å; H306-H398 WeakPolarHBondContact CB-NE2 3.48Å; H306-H398 AromaticContact CD2-CD2 3.41Å; H306-H398 PolarHBondContact CD2-CD2 3.48Å; H306-H398 VanDerWaalsContact CD2-CD2 3.41Å; H306-H398 AromaticContact CD2-CE1 3.87Å; H306-H398 AromaticContact CD2-NE2 2.86Å; H306-H398 PolarHBondContact CD2-NE2 3.41Å; H306-H398 AromaticContact CG-CD2 3.93Å; H306-H398 AromaticContact CG-CE1 3.72Å; H306-H398 AromaticContact CG-NE2 3.15Å; H306-H398 AromaticContact NE2-CD2 3.74Å; H306-H398 AromaticContact NE2-NE2 3.7Å
307	H	48.6	Very low	60.6	Low	20 Å²	20	37.5 Å²	37.5	9%	0.093	22%	0.22	C	C	.	.	G	3₁₀ helix	trans	-63.3	-14.6	-177.5	-141.5	-88.7	0	0	0	115	R220 I223 V224 V300 F305 H314	R220-H307 PolarHBondContact NH2-O 2.63Å; I223-H307 VanDerWaalsContact CG2-CE1 3.43Å; I223-H307 WeakPolarHBondContact CG2-CE1 3.35Å; V224-H307 WeakPolarHBondContact CG2-ND1 3.15Å; V300-H307 WeakPolarHBondContact CG2-CD2 3.43Å; V300-H307 WeakPolarHBondContact CG2-NE2 3.42Å; F305-H307 VanDerWaalsContact C-N 3.26Å; F305-H307 PolarHBondContact O-N 2.98Å; H307-H314 AromaticContact CD2-CE1 3.75Å; H307-H314 AromaticContact CE1-CE1 3.63Å; H307-H314 AromaticContact NE2-CE1 3.3Å; H307-H314 PolarHBondContact NE2-CE1 3.36Å; H307-H314 VanDerWaalsContact NE2-CE1 3.3Å; H307-H314 AromaticContact NE2-ND1 3.9Å
308	V	46.5	Very low	60.8	Low	90 Å²	90	35.7 Å²	35.7	55%	0.545	21%	0.209	S	C	.	.	G	3₁₀ helix	trans	-85.3	-25.9	179.6	-177.6	0	0	0	0	111.8	R220 H306	R220-V308 PolarHBondContact NH2-O 2.84Å; R220-V308 VanDerWaalsContact NH2-O 3.12Å; H306-V308 PolarHBondContact O-N 3.46Å
309	F	47	Very low	61.3	Low	16 Å²	16	32.8 Å²	32.8	7%	0.07	19%	0.191	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.3	-5.9	-158.9	-56.1	-49.2	0	0	0	117.1	F305 H306 P311 F379 L484 H488	F305-F309 AromaticContact CD1-CE2 3.91Å; F305-F309 HydrophobicContact CD1-CE2 3.91Å; F305-F309 AromaticContact CD2-CE2 3.96Å; F305-F309 HydrophobicContact CD2-CE2 3.96Å; F305-F309 HydrophobicContact CD2-CZ 4.34Å; F305-F309 HydrophobicContact CE1-CD2 4.16Å; F305-F309 AromaticContact CE1-CE2 3.27Å; F305-F309 HydrophobicContact CE1-CE2 3.27Å; F305-F309 AromaticContact CE1-CZ 3.91Å; F305-F309 HydrophobicContact CE1-CZ 3.91Å; F305-F309 AromaticContact CE2-CE2 3.41Å; F305-F309 HydrophobicContact CE2-CE2 3.41Å; F305-F309 VanDerWaalsContact CE2-CE2 3.41Å; F305-F309 AromaticContact CE2-CZ 3.44Å; F305-F309 HydrophobicContact CE2-CZ 3.44Å; F305-F309 VanDerWaalsContact CE2-CZ 3.44Å; F305-F309 HydrophobicContact CG-CE2 4.2Å; F305-F309 HydrophobicContact CZ-CD2 4.19Å; F305-F309 HydrophobicContact CZ-CE1 4.45Å; F305-F309 AromaticContact CZ-CE2 2.97Å; F305-F309 HydrophobicContact CZ-CE2 2.97Å; F305-F309 AromaticContact CZ-CZ 3.12Å; F305-F309 HydrophobicContact CZ-CZ 3.12Å; F305-F309 WeakPolarHBondContact O-CE2 3.34Å; H306-F309 PolarHBondContact O-N 3.27Å; H306-F309 VanDerWaalsContact O-N 3.11Å; F309-P311 WeakPolarHBondContact O-CD 3.31Å; F309-F379 HydrophobicContact CD1-CE1 4.35Å; F309-F379 AromaticContact CE1-CD1 3.94Å; F309-F379 HydrophobicContact CE1-CD1 3.94Å; F309-F379 AromaticContact CE1-CE1 3.46Å; F309-F379 HydrophobicContact CE1-CE1 3.46Å; F309-F379 VanDerWaalsContact CE1-CE1 3.46Å; F309-F379 HydrophobicContact CE1-CZ 4.35Å; F309-F379 HydrophobicContact CE2-CD1 4.4Å; F309-F379 HydrophobicContact CE2-CE1 4.04Å; F309-F379 HydrophobicContact CE2-CZ 4.38Å; F309-F379 AromaticContact CZ-CD1 3.49Å; F309-F379 HydrophobicContact CZ-CD1 3.49Å; F309-F379 VanDerWaalsContact CZ-CD1 3.49Å; F309-F379 AromaticContact CZ-CE1 3.28Å; F309-F379 HydrophobicContact CZ-CE1 3.28Å; F309-F379 HydrophobicContact CZ-CG 4.29Å; F309-F379 HydrophobicContact CZ-CZ 4.04Å; F309-L484 HydrophobicContact CB-CD2 4.34Å; F309-L484 HydrophobicContact CD1-CD1 4.42Å; F309-L484 HydrophobicContact CD1-CD2 2.89Å; F309-L484 HydrophobicContact CD1-CG 4.08Å; F309-L484 HydrophobicContact CE1-CD1 3.86Å; F309-L484 HydrophobicContact CE1-CD2 3.18Å; F309-L484 HydrophobicContact CE1-CG 3.93Å; F309-L484 HydrophobicContact CG-CD2 3.77Å; F309-L484 HydrophobicContact CZ-CD2 4.32Å; F309-H488 PolarHBondContact O-CE1 3.46Å
310	Y	53.7	Low	62.3	Low	9 Å²	9	32.5 Å²	32.5	4%	0.035	19%	0.189	C	C	.	.			trans	-128.5	72.8	-168	-63.3	-70.8	0	0	0	113.6	H306 S312 E313 H314 F357 T361 L365	H306-Y310 HydrophobicContact CB-CD2 4.49Å; H306-Y310 HydrophobicContact CB-CE2 4.2Å; H306-Y310 WeakPolarHBondContact O-CD2 3.44Å; Y310-S312 PolarHBondContact O-N 3.28Å; Y310-E313 VanDerWaalsContact CB-OE2 3.26Å; Y310-E313 WeakPolarHBondContact CB-OE2 3.39Å; Y310-E313 HydrophobicContact CD1-CG 3.96Å; Y310-E313 WeakPolarHBondContact CD1-OE1 3.04Å; Y310-E313 WeakPolarHBondContact CD1-OE2 3.3Å; Y310-E313 VanDerWaalsContact CD2-OE2 3.31Å; Y310-E313 WeakPolarHBondContact CD2-OE2 3.38Å; Y310-E313 WeakPolarHBondContact CE1-OE1 3.34Å; Y310-E313 HydrophobicContact CG-CG 4Å; Y310-E313 PolarHBondContact O-N 2.92Å; Y310-H314 PolarHBondContact O-CD2 2.85Å; Y310-H314 VanDerWaalsContact O-CD2 3.22Å; Y310-F357 HydrophobicContact CD1-CE1 4.16Å; Y310-T361 HydrophobicContact CD1-CG2 4.46Å; Y310-T361 HydrophobicContact CE1-CG2 3.38Å; Y310-L365 WeakPolarHBondContact OH-CD1 3.35Å
311	P	46	Very low	63.6	Low	46 Å²	46	34.1 Å²	34.1	30%	0.299	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-14.1	174.8	-17.3	28.4	0	0	0	113.9	W216 F309 K315	W216-P311 HydrophobicContact CH2-CB 4.21Å; W216-P311 WeakPolarHBondContact CH2-O 3.4Å; W216-P311 HydrophobicContact CZ2-CB 4.39Å; W216-P311 WeakPolarHBondContact CZ2-O 3.44Å; F309-P311 WeakPolarHBondContact O-CD 3.31Å; P311-K315 WeakPolarHBondContact O-CE 3.47Å
312	S	46.3	Very low	64.4	Low	18 Å²	18	28.4 Å²	28.4	13%	0.126	17%	0.173	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.4	-20.8	-177.1	37.8	0	0	0	0	113.6	Y310 F357	Y310-S312 PolarHBondContact O-N 3.28Å; S312-F357 WeakPolarHBondContact OG-CD1 3.43Å; S312-F357 WeakPolarHBondContact OG-CE1 3.48Å
313	E	52	Low	65.6	Low	14 Å²	14	25.9 Å²	25.9	7%	0.065	15%	0.152	C	C	.	.	G	3₁₀ helix	trans	-75.7	-41.3	-170.8	-66.4	-178.8	168.3	0	0	112	Y310 K315 L316 H358	Y310-E313 VanDerWaalsContact CB-OE2 3.26Å; Y310-E313 WeakPolarHBondContact CB-OE2 3.39Å; Y310-E313 HydrophobicContact CD1-CG 3.96Å; Y310-E313 WeakPolarHBondContact CD1-OE1 3.04Å; Y310-E313 WeakPolarHBondContact CD1-OE2 3.3Å; Y310-E313 VanDerWaalsContact CD2-OE2 3.31Å; Y310-E313 WeakPolarHBondContact CD2-OE2 3.38Å; Y310-E313 WeakPolarHBondContact CE1-OE1 3.34Å; Y310-E313 HydrophobicContact CG-CG 4Å; Y310-E313 PolarHBondContact O-N 2.92Å; E313-K315 PolarHBondContact O-N 3.49Å; E313-L316 WeakPolarHBondContact O-CB 3.25Å; E313-L316 PolarHBondContact O-N 3.22Å; E313-L316 VanDerWaalsContact O-N 3.15Å; E313-H358 HydrophobicContact CG-CB 4.25Å; E313-H358 WeakPolarHBondContact CG-ND1 3.33Å; E313-H358 IonicContact OE1-CE1 3.1Å; E313-H358 IonicContact OE1-CG 3.76Å; E313-H358 IonicContact OE1-ND1 3.6Å; E313-H358 PolarHBondContact OE1-ND1 2.79Å; E313-H358 IonicContact OE2-CE1 3.63Å; E313-H358 IonicContact OE2-ND1 2.62Å; E313-H358 PolarHBondContact OE2-ND1 3.5Å
314	H	61	Low	67.4	Low	7 Å²	7	23.1 Å²	23.1	3%	0.032	12%	0.123	C	C	.	.	G	3₁₀ helix	trans	-73.1	-1.9	-179.3	-29.3	-99.7	0	0	0	114	W216 D296 H307 Y310 L316 F318	W216-H314 VanDerWaalsContact NE1-CB 3.33Å; D296-H314 IonicContact OD1-CE1 2.8Å; D296-H314 IonicContact OD1-CG 3.95Å; D296-H314 IonicContact OD1-ND1 3.77Å; D296-H314 PolarHBondContact OD1-ND1 3.28Å; D296-H314 IonicContact OD2-ND1 3.54Å; H307-H314 AromaticContact CD2-CE1 3.75Å; H307-H314 AromaticContact CE1-CE1 3.63Å; H307-H314 AromaticContact NE2-CE1 3.3Å; H307-H314 PolarHBondContact NE2-CE1 3.36Å; H307-H314 VanDerWaalsContact NE2-CE1 3.3Å; H307-H314 AromaticContact NE2-ND1 3.9Å; Y310-H314 PolarHBondContact O-CD2 2.85Å; Y310-H314 VanDerWaalsContact O-CD2 3.22Å; H314-L316 VanDerWaalsContact C-N 3.32Å; H314-F318 VanDerWaalsContact O-CD2 3.22Å; H314-F318 WeakPolarHBondContact O-CD2 3.3Å; H314-F318 WeakPolarHBondContact O-CE2 3.33Å
315	K	73.2	Confident	68.9	Low	44 Å²	44	25 Å²	25	19%	0.191	14%	0.14	C	C	.	.	G	3₁₀ helix	trans	-76.2	-23.5	172.6	-59.6	-173.4	-171.1	-163.8	0	112	W216 P311 E313 F318 Y319	W216-K315 HydrophobicContact CD2-CD 4.25Å; W216-K315 HydrophobicContact CD2-CG 3.57Å; W216-K315 HydrophobicContact CE3-CD 4.29Å; W216-K315 VanDerWaalsContact CE3-CE 3.43Å; W216-K315 HydrophobicContact CE3-CG 4.12Å; W216-K315 HydrophobicContact CG-CG 3.7Å; W216-K315 HydrophobicContact CZ2-CG 4.47Å; P311-K315 WeakPolarHBondContact O-CE 3.47Å; E313-K315 PolarHBondContact O-N 3.49Å; K315-F318 WeakPolarHBondContact O-CB 3.13Å; K315-F318 PolarHBondContact O-N 3.42Å; K315-F318 VanDerWaalsContact O-N 3.09Å; K315-Y319 HydrophobicContact CB-CD2 4.42Å; K315-Y319 HydrophobicContact CB-CE2 3.74Å; K315-Y319 PolarHBondContact O-N 2.94Å
316	L	81.2	Confident	70.8	Confident	5 Å²	5	25.3 Å²	25.3	3%	0.026	14%	0.142	C	C	.	.	H	α-helix	trans	-60.7	-44.7	-169.9	-174.2	62.4	0	0	0	113.4	F292 E313 H314 F318 Y319 L320 A354 T355 V408	F292-L316 HydrophobicContact CD1-CD2 4.4Å; F292-L316 HydrophobicContact CD2-CD2 3.67Å; F292-L316 HydrophobicContact CD2-CG 4.22Å; F292-L316 HydrophobicContact CE1-CD2 4.07Å; F292-L316 HydrophobicContact CE2-CD2 3.28Å; F292-L316 HydrophobicContact CE2-CG 4.22Å; F292-L316 HydrophobicContact CG-CD2 4.23Å; F292-L316 HydrophobicContact CZ-CD2 3.51Å; E313-L316 WeakPolarHBondContact O-CB 3.25Å; E313-L316 PolarHBondContact O-N 3.22Å; E313-L316 VanDerWaalsContact O-N 3.15Å; H314-L316 VanDerWaalsContact C-N 3.32Å; L316-F318 PolarHBondContact O-N 3.24Å; L316-Y319 PolarHBondContact O-N 2.8Å; L316-L320 HydrophobicContact CD1-CD1 3.98Å; L316-L320 HydrophobicContact CD1-CD2 4.2Å; L316-L320 HydrophobicContact CD1-CG 3.87Å; L316-L320 HydrophobicContact CD2-CD1 4.24Å; L316-L320 HydrophobicContact CG-CD1 3.67Å; L316-L320 HydrophobicContact CG-CG 4.03Å; L316-L320 VanDerWaalsContact O-CG 3.31Å; L316-L320 WeakPolarHBondContact O-CG 3.41Å; L316-L320 PolarHBondContact O-N 3.23Å; L316-A354 HydrophobicContact CD1-CB 4.16Å; L316-T355 HydrophobicContact CD1-CG2 3.83Å; L316-T355 HydrophobicContact CD2-CG2 3.62Å; L316-T355 HydrophobicContact CG-CG2 4.41Å; L316-V408 HydrophobicContact CD1-CG1 4.22Å
317	P	84.8	Confident	72.5	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.013	14%	0.137	C	C	.	.	H	α-helix	trans	-54.3	-40.3	173.3	-26.6	34.5	0	0	0	113.7	F292 S293 Y319 L320 I321	F292-P317 HydrophobicContact CB-CG 3.77Å; S293-P317 VanDerWaalsContact OG-CB 3.29Å; S293-P317 WeakPolarHBondContact OG-CB 2.93Å; P317-Y319 PolarHBondContact O-N 3.47Å; P317-L320 PolarHBondContact O-N 3.12Å; P317-I321 WeakPolarHBondContact O-CB 3.39Å; P317-I321 WeakPolarHBondContact O-CG1 3.38Å; P317-I321 PolarHBondContact O-N 3.31Å
318	F	81.8	Confident	74.4	Confident	36 Å²	36	24.3 Å²	24.3	16%	0.158	14%	0.137	C	C	.	.	H	α-helix	trans	-73.5	-12.8	-178.4	-57.6	-81.4	0	0	0	113.6	V212 L215 W216 Y219 H314 K315 L316 P322	V212-F318 HydrophobicContact CG1-CB 3.69Å; L215-F318 HydrophobicContact CB-CE1 4.43Å; L215-F318 HydrophobicContact CD2-CD1 3.72Å; L215-F318 HydrophobicContact CD2-CE1 3.53Å; L215-F318 HydrophobicContact CG-CD1 4.08Å; L215-F318 HydrophobicContact CG-CE1 3.55Å; L215-F318 HydrophobicContact CG-CZ 4.29Å; W216-F318 HydrophobicContact CB-CD2 3.99Å; W216-F318 HydrophobicContact CB-CE2 4.03Å; Y219-F318 AromaticContact CD1-CE2 3.94Å; Y219-F318 HydrophobicContact CD1-CE2 3.94Å; Y219-F318 AromaticContact CD1-CZ 3.95Å; Y219-F318 HydrophobicContact CD1-CZ 3.95Å; Y219-F318 HydrophobicContact CD2-CZ 4.36Å; Y219-F318 HydrophobicContact CE1-CE2 4.49Å; Y219-F318 HydrophobicContact CG-CE2 4.26Å; Y219-F318 AromaticContact CG-CZ 3.8Å; Y219-F318 HydrophobicContact CG-CZ 3.8Å; H314-F318 VanDerWaalsContact O-CD2 3.22Å; H314-F318 WeakPolarHBondContact O-CD2 3.3Å; H314-F318 WeakPolarHBondContact O-CE2 3.33Å; K315-F318 WeakPolarHBondContact O-CB 3.13Å; K315-F318 PolarHBondContact O-N 3.42Å; K315-F318 VanDerWaalsContact O-N 3.09Å; L316-F318 PolarHBondContact O-N 3.24Å; F318-P322 WeakPolarHBondContact O-CD 3.47Å; F318-P322 WeakPolarHBondContact O-CG 3.37Å
319	Y	86.3	Confident	76.2	Confident	12 Å²	12	20.7 Å²	20.7	5%	0.047	12%	0.117	C	C	.	.	H	α-helix	trans	-93.5	-44	167.7	-57.4	-37.4	0	0	0	111.8	V212 Q213 K315 L316 P317 A323 L347 F350 S351	V212-Y319 HydrophobicContact CG1-CD1 4.33Å; V212-Y319 HydrophobicContact CG1-CE1 3.96Å; Q213-Y319 PolarHBondContact NE2-OH 2.96Å; Q213-Y319 VanDerWaalsContact NE2-OH 3.11Å; K315-Y319 HydrophobicContact CB-CD2 4.42Å; K315-Y319 HydrophobicContact CB-CE2 3.74Å; K315-Y319 PolarHBondContact O-N 2.94Å; L316-Y319 PolarHBondContact O-N 2.8Å; P317-Y319 PolarHBondContact O-N 3.47Å; Y319-A323 WeakPolarHBondContact O-CB 3.44Å; Y319-A323 PolarHBondContact O-N 3.15Å; Y319-L347 HydrophobicContact CD1-CD2 4.21Å; Y319-F350 HydrophobicContact CD2-CB 4.15Å; Y319-F350 HydrophobicContact CE2-CB 4.13Å; Y319-F350 HydrophobicContact CG-CB 4.39Å; Y319-S351 WeakPolarHBondContact CB-OG 3.5Å
320	L	91.2	Very high	77.8	Confident	0 Å²	0	20 Å²	20	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-68.7	-45.2	-173.7	-66	178.1	0	0	0	113.3	L285 F292 L316 P317 A323 G324 V408	L285-L320 HydrophobicContact CD2-CD2 3.83Å; F292-L320 HydrophobicContact CD2-CD1 3.99Å; F292-L320 HydrophobicContact CE2-CD1 4.22Å; L316-L320 HydrophobicContact CD1-CD1 3.98Å; L316-L320 HydrophobicContact CD1-CD2 4.2Å; L316-L320 HydrophobicContact CD1-CG 3.87Å; L316-L320 HydrophobicContact CD2-CD1 4.24Å; L316-L320 HydrophobicContact CG-CD1 3.67Å; L316-L320 HydrophobicContact CG-CG 4.03Å; L316-L320 VanDerWaalsContact O-CG 3.31Å; L316-L320 WeakPolarHBondContact O-CG 3.41Å; L316-L320 PolarHBondContact O-N 3.23Å; P317-L320 PolarHBondContact O-N 3.12Å; L320-A323 PolarHBondContact O-N 3.49Å; L320-G324 PolarHBondContact O-N 2.9Å; L320-V408 HydrophobicContact CD1-CG1 3.93Å; L320-V408 HydrophobicContact CD1-CG2 4.03Å; L320-V408 HydrophobicContact CD2-CG1 3.5Å; L320-V408 VanDerWaalsContact CD2-CG1 3.5Å; L320-V408 HydrophobicContact CG-CG1 4.28Å
321	I	90.1	Very high	79	Confident	68 Å²	68	20.4 Å²	20.4	35%	0.349	12%	0.117	S	C	.	.	H	α-helix	trans	-64.4	-50.4	-177.6	-63.8	169.5	0	0	0	110.2	P317 A323 G324 A325	P317-I321 WeakPolarHBondContact O-CB 3.39Å; P317-I321 WeakPolarHBondContact O-CG1 3.38Å; P317-I321 PolarHBondContact O-N 3.31Å; I321-A323 PolarHBondContact O-N 3.44Å; I321-G324 PolarHBondContact O-N 3.44Å; I321-A325 WeakPolarHBondContact O-CB 3.49Å; I321-A325 PolarHBondContact O-N 3.37Å
322	P	86.7	Confident	80.3	Confident	41 Å²	41	26.6 Å²	26.6	27%	0.266	13%	0.134	S	C	.	.	H	α-helix	trans	-61.1	-42.7	173.4	-26.4	38.7	0	0	0	112.5	F318 G324 A325 F326 L347	F318-P322 WeakPolarHBondContact O-CD 3.47Å; F318-P322 WeakPolarHBondContact O-CG 3.37Å; P322-G324 VanDerWaalsContact C-N 3.34Å; P322-G324 PolarHBondContact O-N 3.03Å; P322-A325 PolarHBondContact O-N 3.09Å; P322-F326 HydrophobicContact CB-CD2 4.17Å; P322-F326 HydrophobicContact CB-CE2 4.1Å; P322-F326 WeakPolarHBondContact O-CB 3.45Å; P322-F326 WeakPolarHBondContact O-CD2 3.34Å; P322-F326 PolarHBondContact O-N 3Å; P322-L347 HydrophobicContact CB-CD1 3.97Å
323	A	89.5	Confident	81.2	Confident	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-58	-45.3	178.9	0	0	0	0	0	112.1	L285 Y319 L320 I321 F326 A327 L347 L348	L285-A323 HydrophobicContact CD1-CB 4.09Å; Y319-A323 WeakPolarHBondContact O-CB 3.44Å; Y319-A323 PolarHBondContact O-N 3.15Å; L320-A323 PolarHBondContact O-N 3.49Å; I321-A323 PolarHBondContact O-N 3.44Å; A323-F326 PolarHBondContact O-N 2.95Å; A323-A327 VanDerWaalsContact O-CB 3.26Å; A323-A327 WeakPolarHBondContact O-CB 3.41Å; A323-A327 PolarHBondContact O-N 3.43Å; A323-L347 HydrophobicContact CB-CB 3.86Å; A323-L347 HydrophobicContact CB-CD1 4.09Å; A323-L348 HydrophobicContact CB-CD2 4.47Å
324	G	91.8	Very high	81.7	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-66.4	-40.8	176.5	0	0	0	0	0	113	G282 L320 I321 P322 A327 I328	G282-G324 VanDerWaalsContact O-CA 3.32Å; G282-G324 WeakPolarHBondContact O-CA 3.33Å; L320-G324 PolarHBondContact O-N 2.9Å; I321-G324 PolarHBondContact O-N 3.44Å; P322-G324 VanDerWaalsContact C-N 3.34Å; P322-G324 PolarHBondContact O-N 3.03Å; G324-A327 PolarHBondContact O-N 2.7Å; G324-I328 WeakPolarHBondContact O-CG1 3.22Å; G324-I328 PolarHBondContact O-N 3.03Å
325	A	89.5	Confident	81.7	Confident	50 Å²	50	42.5 Å²	42.5	41%	0.413	20%	0.199	S	C	.	.	H	α-helix	trans	-62.7	-45.2	175.7	0	0	0	0	0	112	I321 P322 I328 A329	I321-A325 WeakPolarHBondContact O-CB 3.49Å; I321-A325 PolarHBondContact O-N 3.37Å; P322-A325 PolarHBondContact O-N 3.09Å; A325-I328 PolarHBondContact O-N 2.97Å; A325-A329 VanDerWaalsContact O-CB 3.26Å; A325-A329 WeakPolarHBondContact O-CB 3.38Å; A325-A329 PolarHBondContact O-N 2.9Å
326	F	87	Confident	81.3	Confident	32 Å²	32	44.2 Å²	44.2	14%	0.14	21%	0.205	C	C	.	.	H	α-helix	trans	-67.7	-35.8	176.5	-76.3	-69.1	0	0	0	112.2	F246 P322 A323 A329 S330 C340 V343 V344 L347	F246-F326 HydrophobicContact CD2-CD1 4.43Å; F246-F326 AromaticContact CD2-CE1 3.45Å; F246-F326 HydrophobicContact CD2-CE1 3.45Å; F246-F326 VanDerWaalsContact CD2-CE1 3.45Å; F246-F326 AromaticContact CD2-CZ 3.49Å; F246-F326 HydrophobicContact CD2-CZ 3.49Å; F246-F326 VanDerWaalsContact CD2-CZ 3.49Å; F246-F326 AromaticContact CE2-CD1 3.74Å; F246-F326 HydrophobicContact CE2-CD1 3.74Å; F246-F326 AromaticContact CE2-CE1 3.14Å; F246-F326 HydrophobicContact CE2-CE1 3.14Å; F246-F326 AromaticContact CE2-CZ 3.64Å; F246-F326 HydrophobicContact CE2-CZ 3.64Å; F246-F326 HydrophobicContact CZ-CE1 4.37Å; P322-F326 HydrophobicContact CB-CD2 4.17Å; P322-F326 HydrophobicContact CB-CE2 4.1Å; P322-F326 WeakPolarHBondContact O-CB 3.45Å; P322-F326 WeakPolarHBondContact O-CD2 3.34Å; P322-F326 PolarHBondContact O-N 3Å; A323-F326 PolarHBondContact O-N 2.95Å; F326-A329 PolarHBondContact O-N 3.38Å; F326-S330 WeakPolarHBondContact O-CB 3.33Å; F326-S330 PolarHBondContact O-N 3.4Å; F326-C340 HydrophobicContact CB-CB 4.42Å; F326-C340 HydrophobicContact CD1-CB 4.36Å; F326-V343 HydrophobicContact CD2-CG1 3.82Å; F326-V343 HydrophobicContact CE1-CG1 4.4Å; F326-V343 HydrophobicContact CE2-CG1 3.79Å; F326-V343 HydrophobicContact CG-CG1 4.24Å; F326-V343 HydrophobicContact CZ-CG1 4.08Å; F326-V344 HydrophobicContact CB-CG2 3.39Å; F326-L347 HydrophobicContact CD2-CD1 3.99Å; F326-L347 HydrophobicContact CE2-CD1 4.32Å
327	A	88.5	Confident	80.9	Confident	0 Å²	0	44 Å²	44	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-60.2	-49.2	174.2	0	0	0	0	0	110.8	A323 G324 A329 S330 V344 F419	A323-A327 VanDerWaalsContact O-CB 3.26Å; A323-A327 WeakPolarHBondContact O-CB 3.41Å; A323-A327 PolarHBondContact O-N 3.43Å; G324-A327 PolarHBondContact O-N 2.7Å; A327-A329 PolarHBondContact O-N 3.49Å; A327-S330 PolarHBondContact O-N 2.89Å; A327-S330 PolarHBondContact O-OG 2.95Å; A327-V344 HydrophobicContact CB-CG1 4.39Å; A327-V344 HydrophobicContact CB-CG2 4.22Å; A327-F419 HydrophobicContact CB-CE1 4.29Å; A327-F419 HydrophobicContact CB-CE2 4.32Å; A327-F419 HydrophobicContact CB-CZ 3.58Å
328	I	89.3	Confident	80.2	Confident	21 Å²	21	44.4 Å²	44.4	11%	0.108	21%	0.205	C	C	.	.	H	α-helix	trans	-64.8	-42.2	176.9	-63.9	167.4	0	0	0	111	L283 I286 G324 A325 S330 I331 R332	L283-I328 HydrophobicContact CD2-CD1 3.96Å; L283-I328 HydrophobicContact CG-CD1 4.09Å; I286-I328 HydrophobicContact CD1-CD1 3.85Å; G324-I328 WeakPolarHBondContact O-CG1 3.22Å; G324-I328 PolarHBondContact O-N 3.03Å; A325-I328 PolarHBondContact O-N 2.97Å; I328-S330 VanDerWaalsContact C-N 3.28Å; I328-S330 PolarHBondContact O-N 3.17Å; I328-I331 PolarHBondContact O-N 3.47Å; I328-R332 HydrophobicContact CG2-CG 4.38Å; I328-R332 PolarHBondContact O-N 2.92Å; I328-R332 VanDerWaalsContact O-N 3.14Å
329	A	83.3	Confident	79.6	Confident	14 Å²	14	44 Å²	44	12%	0.116	20%	0.203	C	C	.	.	H	α-helix	trans	-62.1	-35	178.3	0	0	0	0	0	112.4	A325 F326 A327 I331 R332 L333	A325-A329 VanDerWaalsContact O-CB 3.26Å; A325-A329 WeakPolarHBondContact O-CB 3.38Å; A325-A329 PolarHBondContact O-N 2.9Å; F326-A329 PolarHBondContact O-N 3.38Å; A327-A329 PolarHBondContact O-N 3.49Å; A329-I331 PolarHBondContact O-N 2.98Å; A329-I331 VanDerWaalsContact O-N 3.12Å; A329-R332 PolarHBondContact O-N 3.18Å; A329-L333 HydrophobicContact CB-CD1 4.45Å; A329-L333 WeakPolarHBondContact O-CB 3.34Å; A329-L333 PolarHBondContact O-N 3.17Å
330	S	79.9	Confident	79.2	Confident	2 Å²	2	43.7 Å²	43.7	1%	0.014	20%	0.203	C	C	.	.	H	α-helix	trans	-62.3	-17.8	178.3	76.4	0	0	0	0	114	F326 A327 I328 S337	F326-S330 WeakPolarHBondContact O-CB 3.33Å; F326-S330 PolarHBondContact O-N 3.4Å; A327-S330 PolarHBondContact O-N 2.89Å; A327-S330 PolarHBondContact O-OG 2.95Å; I328-S330 VanDerWaalsContact C-N 3.28Å; I328-S330 PolarHBondContact O-N 3.17Å; S330-S337 WeakPolarHBondContact O-CB 3.38Å; S330-S337 PolarHBondContact O-OG 3.3Å
331	I	79.7	Confident	78.8	Confident	17 Å²	17	43.7 Å²	43.7	9%	0.087	20%	0.203	C	C	.	.	H	α-helix	trans	-103.5	-44.5	178	-68.5	-174.5	0	0	0	111.6	R275 I278 I328 A329 L333	R275-I331 HydrophobicContact CG-CD1 4.37Å; R275-I331 HydrophobicContact CG-CG2 3.62Å; I278-I331 HydrophobicContact CB-CD1 3.27Å; I278-I331 HydrophobicContact CB-CG1 4.42Å; I278-I331 HydrophobicContact CD1-CD1 3.69Å; I278-I331 HydrophobicContact CD1-CG1 4.4Å; I278-I331 HydrophobicContact CG1-CD1 4.05Å; I278-I331 HydrophobicContact CG2-CD1 3.24Å; I278-I331 HydrophobicContact CG2-CG1 3.95Å; I328-I331 PolarHBondContact O-N 3.47Å; A329-I331 PolarHBondContact O-N 2.98Å; A329-I331 VanDerWaalsContact O-N 3.12Å; I331-L333 PolarHBondContact O-N 3.17Å
332	R	74.1	Confident	78.4	Confident	176 Å²	176	40.6 Å²	40.6	66%	0.664	19%	0.187	S	C	*	.	H	α-helix	trans	-69.6	-25.3	-176.9	-70.9	-170.9	175.7	170.1	-0.6	112.2	I328 A329	I328-R332 HydrophobicContact CG2-CG 4.38Å; I328-R332 PolarHBondContact O-N 2.92Å; I328-R332 VanDerWaalsContact O-N 3.14Å; A329-R332 PolarHBondContact O-N 3.18Å
333	L	64.5	Low	78.1	Confident	71 Å²	71	40.5 Å²	40.5	37%	0.372	19%	0.186	S	C	.	.			trans	-122.7	80.4	-175.5	-57.4	168	0	0	0	107.6	A329 I331 R335 R336 S337	A329-L333 HydrophobicContact CB-CD1 4.45Å; A329-L333 WeakPolarHBondContact O-CB 3.34Å; A329-L333 PolarHBondContact O-N 3.17Å; I331-L333 PolarHBondContact O-N 3.17Å; L333-R335 PolarHBondContact O-N 3.15Å; L333-R336 HydrophobicContact CB-CB 4.01Å; L333-R336 HydrophobicContact CB-CG 3.92Å; L333-R336 HydrophobicContact CD1-CG 4.46Å; L333-R336 WeakPolarHBondContact O-CA 3.36Å; L333-R336 PolarHBondContact O-N 2.64Å; L333-S337 PolarHBondContact O-N 3.36Å
334	E	62.5	Low	78	Confident	99 Å²	99	40.5 Å²	40.5	46%	0.463	19%	0.186	S	C	.	.	G	3₁₀ helix	trans	-47.2	-35.8	-177.9	-66	176.9	-178	0	0	112.6	R336 S337	E334-R336 VanDerWaalsContact C-N 3.29Å; E334-R336 PolarHBondContact O-N 3.23Å; E334-S337 PolarHBondContact O-OG 3.09Å
335	R	61.4	Low	77.9	Confident	202 Å²	202	40.7 Å²	40.7	76%	0.762	19%	0.187	S	C	*	.	G	3₁₀ helix	trans	-73.4	-14.4	179.1	-62.9	-177.6	-179.4	169.4	-2.5	114.6	L333	L333-R335 PolarHBondContact O-N 3.15Å
336	R	64.8	Low	77.7	Confident	80 Å²	80	39.1 Å²	39.1	30%	0.302	17%	0.171	S	C	.	.	G	3₁₀ helix	trans	-101.8	-13.7	-179.3	-62.2	-168.3	-174.2	174.4	0.5	113	L333 E334 F338 Y339 C340	L333-R336 HydrophobicContact CB-CB 4.01Å; L333-R336 HydrophobicContact CB-CG 3.92Å; L333-R336 HydrophobicContact CD1-CG 4.46Å; L333-R336 WeakPolarHBondContact O-CA 3.36Å; L333-R336 PolarHBondContact O-N 2.64Å; E334-R336 VanDerWaalsContact C-N 3.29Å; E334-R336 PolarHBondContact O-N 3.23Å; R336-F338 PolarHBondContact O-N 2.91Å; R336-F338 VanDerWaalsContact O-N 3.12Å; R336-Y339 PolarHBondContact O-N 3.14Å; R336-Y339 VanDerWaalsContact O-N 3.09Å; R336-C340 PolarHBondContact O-N 3.29Å; R336-C340 VanDerWaalsContact O-N 3.08Å; R336-C340 PolarHBondContact O-SG 3.32Å; R336-C340 VanDerWaalsContact O-SG 3.34Å
337	S	71.7	Confident	77.8	Confident	1 Å²	1	38.9 Å²	38.9	1%	0.007	17%	0.171	C	C	.	.	H	α-helix	trans	-51.6	-38	-177.3	-47.1	0	0	0	0	113	S330 L333 E334 Y339 C340 I341 Y426	S330-S337 WeakPolarHBondContact O-CB 3.38Å; S330-S337 PolarHBondContact O-OG 3.3Å; L333-S337 PolarHBondContact O-N 3.36Å; E334-S337 PolarHBondContact O-OG 3.09Å; S337-Y339 PolarHBondContact O-N 3.25Å; S337-Y339 VanDerWaalsContact O-N 3.15Å; S337-C340 PolarHBondContact O-N 3.06Å; S337-I341 WeakPolarHBondContact O-CB 3.32Å; S337-I341 WeakPolarHBondContact O-CD1 3.38Å; S337-I341 VanDerWaalsContact O-CG1 3.29Å; S337-I341 WeakPolarHBondContact O-CG1 3.39Å; S337-I341 PolarHBondContact O-N 3.38Å; S337-Y426 WeakPolarHBondContact CB-OH 3.28Å
338	F	69.9	Low	77.9	Confident	10 Å²	10	38.9 Å²	38.9	4%	0.044	17%	0.171	C	C	.	.	H	α-helix	trans	-55.1	-32.8	-179.7	-176.7	-91.4	0	0	0	114.4	W263 R336 P342 P518 M519 L522	W263-F338 HydrophobicContact CH2-CB 4.23Å; W263-F338 AromaticContact CH2-CD1 3.86Å; W263-F338 HydrophobicContact CH2-CD1 3.86Å; W263-F338 AromaticContact CH2-CD2 3.34Å; W263-F338 HydrophobicContact CH2-CD2 3.34Å; W263-F338 AromaticContact CH2-CE1 3.97Å; W263-F338 HydrophobicContact CH2-CE1 3.97Å; W263-F338 AromaticContact CH2-CE2 3.5Å; W263-F338 HydrophobicContact CH2-CE2 3.5Å; W263-F338 AromaticContact CH2-CG 3.53Å; W263-F338 HydrophobicContact CH2-CG 3.53Å; W263-F338 AromaticContact CH2-CZ 3.82Å; W263-F338 HydrophobicContact CH2-CZ 3.82Å; W263-F338 HydrophobicContact CZ3-CB 3.87Å; W263-F338 HydrophobicContact CZ3-CD1 4.36Å; W263-F338 AromaticContact CZ3-CD2 3.35Å; W263-F338 HydrophobicContact CZ3-CD2 3.35Å; W263-F338 AromaticContact CZ3-CE2 3.94Å; W263-F338 HydrophobicContact CZ3-CE2 3.94Å; W263-F338 AromaticContact CZ3-CG 3.59Å; W263-F338 HydrophobicContact CZ3-CG 3.59Å; R336-F338 PolarHBondContact O-N 2.91Å; R336-F338 VanDerWaalsContact O-N 3.12Å; F338-P342 WeakPolarHBondContact O-CD 3.49Å; F338-P342 VanDerWaalsContact O-CG 3.31Å; F338-P342 WeakPolarHBondContact O-CG 3.38Å; F338-P518 HydrophobicContact CE2-CB 3.93Å; F338-P518 HydrophobicContact CE2-CG 3.95Å; F338-P518 HydrophobicContact CZ-CB 3.95Å; F338-P518 HydrophobicContact CZ-CG 4.45Å; F338-M519 HydrophobicContact CB-SD 4.32Å; F338-M519 HydrophobicContact CD2-CB 4.49Å; F338-M519 HydrophobicContact CD2-CG 3.1Å; F338-M519 HydrophobicContact CD2-SD 3.65Å; F338-M519 HydrophobicContact CE2-CB 4.31Å; F338-M519 HydrophobicContact CE2-CG 3.22Å; F338-M519 HydrophobicContact CE2-SD 4.34Å; F338-M519 HydrophobicContact CG-CG 3.89Å; F338-M519 HydrophobicContact CG-SD 4.25Å; F338-M519 HydrophobicContact CZ-CG 4.1Å; F338-M519 WeakPolarHBondContact O-CE 3.23Å; F338-L522 HydrophobicContact CD1-CD2 4.01Å; F338-L522 HydrophobicContact CE1-CD2 3.64Å; F338-L522 HydrophobicContact CZ-CD2 4.44Å
339	Y	69.5	Low	77.9	Confident	27 Å²	27	38.1 Å²	38.1	11%	0.106	17%	0.167	C	C	.	.	H	α-helix	trans	-105.6	-37	-176.7	-55.3	-93.8	0	0	0	111.2	L201 T253 R336 S337 I341 P342 V343 L522	L201-Y339 HydrophobicContact CD2-CE1 4.08Å; T253-Y339 HydrophobicContact CG2-CD1 4.3Å; T253-Y339 HydrophobicContact CG2-CD2 3.15Å; T253-Y339 HydrophobicContact CG2-CE1 4.17Å; T253-Y339 HydrophobicContact CG2-CE2 3.02Å; T253-Y339 HydrophobicContact CG2-CG 3.82Å; R336-Y339 PolarHBondContact O-N 3.14Å; R336-Y339 VanDerWaalsContact O-N 3.09Å; S337-Y339 PolarHBondContact O-N 3.25Å; S337-Y339 VanDerWaalsContact O-N 3.15Å; Y339-I341 VanDerWaalsContact C-N 3.32Å; Y339-I341 PolarHBondContact O-N 3.15Å; Y339-P342 WeakPolarHBondContact O-CD 3.49Å; Y339-V343 VanDerWaalsContact O-CG2 3.27Å; Y339-V343 WeakPolarHBondContact O-CG2 3.39Å; Y339-V343 PolarHBondContact O-N 3.36Å; Y339-V343 VanDerWaalsContact O-N 3.15Å; Y339-L522 HydrophobicContact CD1-CD2 3.69Å; Y339-L522 HydrophobicContact CE1-CD2 4.15Å; Y339-L522 HydrophobicContact CG-CD2 4.45Å
340	C	77.6	Confident	78	Confident	7 Å²	7	37.8 Å²	37.8	5%	0.047	16%	0.163	C	C	.	.	H	α-helix	trans	-60.5	-42.2	177.9	-64.1	0	0	0	0	111.4	F326 R336 S337 V343 V344	F326-C340 HydrophobicContact CB-CB 4.42Å; F326-C340 HydrophobicContact CD1-CB 4.36Å; R336-C340 PolarHBondContact O-N 3.29Å; R336-C340 VanDerWaalsContact O-N 3.08Å; R336-C340 PolarHBondContact O-SG 3.32Å; R336-C340 VanDerWaalsContact O-SG 3.34Å; S337-C340 PolarHBondContact O-N 3.06Å; C340-V343 PolarHBondContact O-N 3.33Å; C340-V344 WeakPolarHBondContact O-CB 3.5Å; C340-V344 WeakPolarHBondContact O-CG2 3.29Å; C340-V344 PolarHBondContact O-N 2.92Å
341	I	82.6	Confident	78.5	Confident	0 Å²	0	37.7 Å²	37.7	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-63.6	-48.5	-177.2	-69.1	166.3	0	0	0	112.1	L268 S337 Y339 V343 V344 T345 F419 L422 C423 Y426 M519	L268-I341 HydrophobicContact CD2-CD1 4.39Å; S337-I341 WeakPolarHBondContact O-CB 3.32Å; S337-I341 WeakPolarHBondContact O-CD1 3.38Å; S337-I341 VanDerWaalsContact O-CG1 3.29Å; S337-I341 WeakPolarHBondContact O-CG1 3.39Å; S337-I341 PolarHBondContact O-N 3.38Å; Y339-I341 VanDerWaalsContact C-N 3.32Å; Y339-I341 PolarHBondContact O-N 3.15Å; I341-V343 PolarHBondContact O-N 2.85Å; I341-V344 PolarHBondContact O-N 2.63Å; I341-T345 PolarHBondContact O-N 3.42Å; I341-T345 PolarHBondContact O-OG1 3.07Å; I341-F419 HydrophobicContact CB-CD1 4.23Å; I341-F419 HydrophobicContact CG1-CD1 4.05Å; I341-F419 HydrophobicContact CG1-CE1 4.32Å; I341-F419 HydrophobicContact CG2-CB 4.34Å; I341-F419 HydrophobicContact CG2-CD1 4.02Å; I341-F419 WeakPolarHBondContact CG2-O 3.31Å; I341-L422 HydrophobicContact CD1-CB 4.16Å; I341-L422 HydrophobicContact CD1-CD1 4.43Å; I341-L422 HydrophobicContact CG2-CB 3.93Å; I341-C423 VanDerWaalsContact CG2-SG 3.54Å; I341-Y426 HydrophobicContact CD1-CE2 3.83Å; I341-M519 HydrophobicContact CB-CE 3.53Å; I341-M519 HydrophobicContact CD1-CE 3.82Å; I341-M519 HydrophobicContact CG1-CE 4.21Å; I341-M519 HydrophobicContact CG2-CE 3.72Å
342	P	81.8	Confident	79	Confident	3 Å²	3	38.8 Å²	38.8	2%	0.019	17%	0.167	C	C	.	.	H	α-helix	trans	-57.7	-44.7	172	-31.3	37.2	0	0	0	113.5	F338 Y339 T345 I346 M519 L522 A523	F338-P342 WeakPolarHBondContact O-CD 3.49Å; F338-P342 VanDerWaalsContact O-CG 3.31Å; F338-P342 WeakPolarHBondContact O-CG 3.38Å; Y339-P342 WeakPolarHBondContact O-CD 3.49Å; P342-T345 WeakPolarHBondContact O-CB 3.43Å; P342-T345 PolarHBondContact O-N 3.15Å; P342-I346 WeakPolarHBondContact O-CG1 3.26Å; P342-I346 PolarHBondContact O-N 3.3Å; P342-M519 HydrophobicContact CG-CE 4.25Å; P342-L522 HydrophobicContact CB-CD2 4.48Å; P342-L522 HydrophobicContact CB-CG 4.33Å; P342-L522 HydrophobicContact CG-CB 4.43Å; P342-L522 HydrophobicContact CG-CD2 4.12Å; P342-L522 HydrophobicContact CG-CG 4.29Å; P342-A523 HydrophobicContact CB-CB 3.99Å; P342-A523 HydrophobicContact CG-CB 4.39Å
343	V	81.3	Confident	79.5	Confident	39 Å²	39	31.4 Å²	31.4	24%	0.236	14%	0.14	C	C	.	.	H	α-helix	trans	-63	-44.6	179.3	172.3	0	0	0	0	111.2	F326 Y339 C340 I341 T345 I346 L347	F326-V343 HydrophobicContact CD2-CG1 3.82Å; F326-V343 HydrophobicContact CE1-CG1 4.4Å; F326-V343 HydrophobicContact CE2-CG1 3.79Å; F326-V343 HydrophobicContact CG-CG1 4.24Å; F326-V343 HydrophobicContact CZ-CG1 4.08Å; Y339-V343 VanDerWaalsContact O-CG2 3.27Å; Y339-V343 WeakPolarHBondContact O-CG2 3.39Å; Y339-V343 PolarHBondContact O-N 3.36Å; Y339-V343 VanDerWaalsContact O-N 3.15Å; C340-V343 PolarHBondContact O-N 3.33Å; I341-V343 PolarHBondContact O-N 2.85Å; V343-T345 VanDerWaalsContact C-N 3.3Å; V343-T345 PolarHBondContact O-N 3.31Å; V343-I346 PolarHBondContact O-N 3.41Å; V343-L347 HydrophobicContact CG1-CD1 3.92Å; V343-L347 HydrophobicContact CG1-CG 4.34Å; V343-L347 WeakPolarHBondContact O-CG 3.45Å; V343-L347 PolarHBondContact O-N 3.29Å
344	V	88.1	Confident	80.5	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-59.2	-43.9	174.9	173.6	0	0	0	0	110.4	F326 A327 C340 I341 I346 L347 L348 F419	F326-V344 HydrophobicContact CB-CG2 3.39Å; A327-V344 HydrophobicContact CB-CG1 4.39Å; A327-V344 HydrophobicContact CB-CG2 4.22Å; C340-V344 WeakPolarHBondContact O-CB 3.5Å; C340-V344 WeakPolarHBondContact O-CG2 3.29Å; C340-V344 PolarHBondContact O-N 2.92Å; I341-V344 PolarHBondContact O-N 2.63Å; V344-I346 VanDerWaalsContact C-N 3.32Å; V344-I346 PolarHBondContact O-N 2.99Å; V344-L347 PolarHBondContact O-N 3.43Å; V344-L348 HydrophobicContact CG1-CD1 3.56Å; V344-L348 HydrophobicContact CG1-CG 4.11Å; V344-L348 WeakPolarHBondContact O-CB 3.27Å; V344-L348 WeakPolarHBondContact O-CG 3.41Å; V344-L348 PolarHBondContact O-N 3.34Å; V344-F419 HydrophobicContact CB-CD1 3.95Å; V344-F419 HydrophobicContact CB-CE1 4.12Å; V344-F419 HydrophobicContact CB-CG 4.25Å; V344-F419 HydrophobicContact CG1-CB 4.5Å; V344-F419 HydrophobicContact CG1-CD1 3.74Å; V344-F419 HydrophobicContact CG1-CD2 3.62Å; V344-F419 HydrophobicContact CG1-CE1 3.78Å; V344-F419 HydrophobicContact CG1-CE2 3.66Å; V344-F419 HydrophobicContact CG1-CG 3.68Å; V344-F419 HydrophobicContact CG1-CZ 3.75Å; V344-F419 HydrophobicContact CG2-CE1 4.3Å
345	T	88.3	Confident	81.7	Confident	3 Å²	3	23.6 Å²	23.6	2%	0.018	10%	0.102	C	C	.	.	H	α-helix	trans	-58.2	-45.4	177.6	-52.2	0	0	0	0	111.1	I341 P342 V343 L348 I349 F419	I341-T345 PolarHBondContact O-N 3.42Å; I341-T345 PolarHBondContact O-OG1 3.07Å; P342-T345 WeakPolarHBondContact O-CB 3.43Å; P342-T345 PolarHBondContact O-N 3.15Å; V343-T345 VanDerWaalsContact C-N 3.3Å; V343-T345 PolarHBondContact O-N 3.31Å; T345-L348 PolarHBondContact O-N 3.3Å; T345-I349 HydrophobicContact CG2-CD1 4.21Å; T345-I349 WeakPolarHBondContact O-CD1 3.28Å; T345-I349 VanDerWaalsContact O-CG1 3.27Å; T345-I349 WeakPolarHBondContact O-CG1 3.22Å; T345-I349 PolarHBondContact O-N 3.06Å; T345-I349 VanDerWaalsContact O-N 3.13Å; T345-F419 WeakPolarHBondContact OG1-CB 3.46Å
346	I	86.4	Confident	83	Confident	18 Å²	18	15 Å²	15	9%	0.092	7%	0.071	C	C	.	.	H	α-helix	trans	-64.5	-49.1	179.3	-65.6	158.9	0	0	0	111.2	P342 V343 V344 L348 I349 F350 G526 I527	P342-I346 WeakPolarHBondContact O-CG1 3.26Å; P342-I346 PolarHBondContact O-N 3.3Å; V343-I346 PolarHBondContact O-N 3.41Å; V344-I346 VanDerWaalsContact C-N 3.32Å; V344-I346 PolarHBondContact O-N 2.99Å; I346-L348 VanDerWaalsContact C-N 3.28Å; I346-L348 PolarHBondContact O-N 2.75Å; I346-I349 PolarHBondContact O-N 3.08Å; I346-I349 VanDerWaalsContact O-N 3.15Å; I346-F350 HydrophobicContact CG2-CD2 3.82Å; I346-F350 HydrophobicContact CG2-CE2 3.68Å; I346-F350 WeakPolarHBondContact O-CD2 3.22Å; I346-F350 PolarHBondContact O-N 3.48Å; I346-G526 VanDerWaalsContact CD1-C 3.49Å; I346-I527 HydrophobicContact CG1-CG1 3.83Å
347	L	88.2	Confident	83.9	Confident	27 Å²	27	11.3 Å²	11.3	14%	0.141	6%	0.057	C	C	.	.	H	α-helix	trans	-62.6	-35.1	-179.7	-69.2	173.2	0	0	0	112.3	Y319 P322 A323 F326 V343 V344 F350 S351	Y319-L347 HydrophobicContact CD1-CD2 4.21Å; P322-L347 HydrophobicContact CB-CD1 3.97Å; A323-L347 HydrophobicContact CB-CB 3.86Å; A323-L347 HydrophobicContact CB-CD1 4.09Å; F326-L347 HydrophobicContact CD2-CD1 3.99Å; F326-L347 HydrophobicContact CE2-CD1 4.32Å; V343-L347 HydrophobicContact CG1-CD1 3.92Å; V343-L347 HydrophobicContact CG1-CG 4.34Å; V343-L347 WeakPolarHBondContact O-CG 3.45Å; V343-L347 PolarHBondContact O-N 3.29Å; V344-L347 PolarHBondContact O-N 3.43Å; L347-F350 PolarHBondContact O-N 3.32Å; L347-S351 WeakPolarHBondContact O-CB 3.22Å; L347-S351 PolarHBondContact O-N 3.3Å; L347-S351 PolarHBondContact O-OG 3.44Å
348	L	91.4	Very high	84.5	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-69.8	-35.2	175.6	-69.8	170.8	0	0	0	112.3	F281 L285 A323 V344 T345 I346 S351 F352 S412 G415 S416 F419	F281-L348 HydrophobicContact CE1-CD1 4.07Å; F281-L348 HydrophobicContact CE1-CD2 4.3Å; F281-L348 HydrophobicContact CZ-CD1 4.11Å; F281-L348 HydrophobicContact CZ-CD2 3.98Å; L285-L348 HydrophobicContact CD1-CD2 3.9Å; L285-L348 HydrophobicContact CD2-CD2 4.09Å; A323-L348 HydrophobicContact CB-CD2 4.47Å; V344-L348 HydrophobicContact CG1-CD1 3.56Å; V344-L348 HydrophobicContact CG1-CG 4.11Å; V344-L348 WeakPolarHBondContact O-CB 3.27Å; V344-L348 WeakPolarHBondContact O-CG 3.41Å; V344-L348 PolarHBondContact O-N 3.34Å; T345-L348 PolarHBondContact O-N 3.3Å; I346-L348 VanDerWaalsContact C-N 3.28Å; I346-L348 PolarHBondContact O-N 2.75Å; L348-S351 PolarHBondContact O-N 3.12Å; L348-F352 WeakPolarHBondContact O-CB 3.29Å; L348-F352 PolarHBondContact O-N 2.89Å; L348-S412 WeakPolarHBondContact O-CB 3.19Å; L348-G415 VanDerWaalsContact CD1-C 3.46Å; L348-S416 WeakPolarHBondContact CB-OG 3.45Å; L348-F419 HydrophobicContact CD1-CD2 3.99Å
349	I	88.9	Confident	85.3	Confident	5 Å²	5	12.1 Å²	12.1	3%	0.026	6%	0.062	C	C	.	.	H	α-helix	trans	-66.2	-40.5	173.5	-63.3	162.4	0	0	0	110.6	T345 I346 F352 H353 I502 F503 A506 I527	T345-I349 HydrophobicContact CG2-CD1 4.21Å; T345-I349 WeakPolarHBondContact O-CD1 3.28Å; T345-I349 VanDerWaalsContact O-CG1 3.27Å; T345-I349 WeakPolarHBondContact O-CG1 3.22Å; T345-I349 PolarHBondContact O-N 3.06Å; T345-I349 VanDerWaalsContact O-N 3.13Å; I346-I349 PolarHBondContact O-N 3.08Å; I346-I349 VanDerWaalsContact O-N 3.15Å; I349-F352 WeakPolarHBondContact O-CB 3.4Å; I349-F352 PolarHBondContact O-N 3.39Å; I349-H353 PolarHBondContact O-N 2.73Å; I349-H353 VanDerWaalsContact O-N 3.15Å; I349-I502 HydrophobicContact CG2-CG2 3.93Å; I349-F503 HydrophobicContact CB-CD1 4.41Å; I349-F503 HydrophobicContact CB-CE1 3.99Å; I349-F503 HydrophobicContact CB-CZ 4.34Å; I349-F503 HydrophobicContact CG2-CD1 3.58Å; I349-F503 HydrophobicContact CG2-CD2 4.04Å; I349-F503 HydrophobicContact CG2-CE1 3.42Å; I349-F503 VanDerWaalsContact CG2-CE1 3.42Å; I349-F503 HydrophobicContact CG2-CE2 3.88Å; I349-F503 HydrophobicContact CG2-CG 3.95Å; I349-F503 HydrophobicContact CG2-CZ 3.59Å; I349-A506 HydrophobicContact CD1-CB 3.69Å; I349-I527 HydrophobicContact CD1-CD1 3.91Å; I349-I527 HydrophobicContact CD1-CG1 4.29Å
350	F	85.9	Confident	86.1	Confident	7 Å²	7	13.4 Å²	13.4	3%	0.031	7%	0.071	C	C	.	.	H	α-helix	trans	-66.4	-38.8	173.2	-80.6	-70.4	0	0	0	112.7	Y209 Y319 I346 L347 F352 H353 A354 M499 F503	Y209-F350 HydrophobicContact CE2-CE1 4.27Å; Y209-F350 HydrophobicContact CE2-CZ 4.26Å; Y319-F350 HydrophobicContact CD2-CB 4.15Å; Y319-F350 HydrophobicContact CE2-CB 4.13Å; Y319-F350 HydrophobicContact CG-CB 4.39Å; I346-F350 HydrophobicContact CG2-CD2 3.82Å; I346-F350 HydrophobicContact CG2-CE2 3.68Å; I346-F350 WeakPolarHBondContact O-CD2 3.22Å; I346-F350 PolarHBondContact O-N 3.48Å; L347-F350 PolarHBondContact O-N 3.32Å; F350-F352 VanDerWaalsContact C-N 3.34Å; F350-H353 PolarHBondContact O-N 3.35Å; F350-A354 PolarHBondContact O-N 3.48Å; F350-M499 HydrophobicContact CD1-CE 4.03Å; F350-M499 HydrophobicContact CE1-CE 4.23Å; F350-F503 HydrophobicContact CD1-CE2 4.44Å; F350-F503 AromaticContact CD1-CZ 3.79Å; F350-F503 HydrophobicContact CD1-CZ 3.79Å; F350-F503 HydrophobicContact CD2-CE1 4.35Å; F350-F503 AromaticContact CD2-CZ 3.99Å; F350-F503 HydrophobicContact CD2-CZ 3.99Å; F350-F503 HydrophobicContact CE1-CE2 4.23Å; F350-F503 AromaticContact CE1-CZ 3.6Å; F350-F503 HydrophobicContact CE1-CZ 3.6Å; F350-F503 HydrophobicContact CE2-CE1 4.05Å; F350-F503 AromaticContact CE2-CZ 3.81Å; F350-F503 HydrophobicContact CE2-CZ 3.81Å; F350-F503 AromaticContact CG-CZ 3.98Å; F350-F503 HydrophobicContact CG-CZ 3.98Å; F350-F503 HydrophobicContact CZ-CE1 4.17Å; F350-F503 AromaticContact CZ-CZ 3.61Å; F350-F503 HydrophobicContact CZ-CZ 3.61Å
351	S	89.6	Confident	86.2	Confident	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-62.6	-43	175.2	-58.1	0	0	0	0	111.1	Y319 L347 L348 H353 A354 T355 S412	Y319-S351 WeakPolarHBondContact CB-OG 3.5Å; L347-S351 WeakPolarHBondContact O-CB 3.22Å; L347-S351 PolarHBondContact O-N 3.3Å; L347-S351 PolarHBondContact O-OG 3.44Å; L348-S351 PolarHBondContact O-N 3.12Å; S351-H353 VanDerWaalsContact C-N 3.34Å; S351-H353 PolarHBondContact O-N 2.85Å; S351-A354 PolarHBondContact O-N 2.7Å; S351-T355 WeakPolarHBondContact O-CG2 3.47Å; S351-T355 PolarHBondContact O-N 3.13Å; S351-T355 PolarHBondContact O-OG1 2.91Å; S351-S412 WeakPolarHBondContact CB-OG 3.45Å
352	F	89.9	Confident	86.2	Confident	39 Å²	39	15.2 Å²	15.2	17%	0.171	8%	0.077	C	C	.	.	H	α-helix	trans	-55.3	-47.8	173.7	170.2	-111.3	0	0	0	111.4	L348 I349 F350 T355 M356 L409 I413 I502	L348-F352 WeakPolarHBondContact O-CB 3.29Å; L348-F352 PolarHBondContact O-N 2.89Å; I349-F352 WeakPolarHBondContact O-CB 3.4Å; I349-F352 PolarHBondContact O-N 3.39Å; F350-F352 VanDerWaalsContact C-N 3.34Å; F352-T355 PolarHBondContact O-OG1 2.87Å; F352-M356 VanDerWaalsContact O-CB 3.3Å; F352-M356 WeakPolarHBondContact O-CB 3.43Å; F352-M356 PolarHBondContact O-N 3.18Å; F352-L409 HydrophobicContact CD2-CD1 3.38Å; F352-L409 HydrophobicContact CD2-CG 4.2Å; F352-L409 HydrophobicContact CE2-CD1 3.48Å; F352-L409 VanDerWaalsContact CE2-CD1 3.48Å; F352-L409 HydrophobicContact CE2-CG 4.2Å; F352-L409 HydrophobicContact CG-CD1 4.41Å; F352-I413 HydrophobicContact CD2-CD1 4.16Å; F352-I413 HydrophobicContact CD2-CG1 3.62Å; F352-I413 HydrophobicContact CE2-CD1 3.78Å; F352-I413 HydrophobicContact CE2-CG1 3.63Å; F352-I502 HydrophobicContact CD1-CD1 3.9Å; F352-I502 HydrophobicContact CD1-CG1 4.44Å; F352-I502 HydrophobicContact CD1-CG2 3.86Å; F352-I502 HydrophobicContact CE1-CB 4.44Å; F352-I502 HydrophobicContact CE1-CD1 3.31Å; F352-I502 HydrophobicContact CE1-CG1 3.73Å; F352-I502 HydrophobicContact CE1-CG2 3.85Å; F352-I502 HydrophobicContact CZ-CD1 4.32Å
353	H	86.2	Confident	86.3	Confident	21 Å²	21	20.1 Å²	20.1	10%	0.097	10%	0.102	C	C	.	.	H	α-helix	trans	-62.5	-48.1	176.3	171.9	-111.9	0	0	0	114	I349 F350 S351 T355 M356 F357 M499	I349-H353 PolarHBondContact O-N 2.73Å; I349-H353 VanDerWaalsContact O-N 3.15Å; F350-H353 PolarHBondContact O-N 3.35Å; S351-H353 VanDerWaalsContact C-N 3.34Å; S351-H353 PolarHBondContact O-N 2.85Å; H353-T355 VanDerWaalsContact C-N 3.3Å; H353-T355 PolarHBondContact O-N 3.02Å; H353-M356 PolarHBondContact O-N 3.41Å; H353-F357 PolarHBondContact O-N 2.94Å; H353-M499 HydrophobicContact CB-CE 3.32Å; H353-M499 HydrophobicContact CB-CG 4.39Å; H353-M499 HydrophobicContact CB-SD 3.25Å; H353-M499 WeakPolarHBondContact CB-SD 3.17Å; H353-M499 WeakPolarHBondContact CD2-CG 3.28Å; H353-M499 PolarHBondContact CD2-SD 2.85Å; H353-M499 WeakPolarHBondContact ND1-CE 3.31Å; H353-M499 VanDerWaalsContact NE2-CG 3.33Å; H353-M499 WeakPolarHBondContact NE2-CG 3.32Å
354	A	84.6	Confident	86.4	Confident	6 Å²	6	20.7 Å²	20.7	5%	0.05	10%	0.1	C	C	.	.	H	α-helix	trans	-59.1	-44.8	-179.1	0	0	0	0	0	110.8	L316 F350 S351 F357 H358	L316-A354 HydrophobicContact CD1-CB 4.16Å; F350-A354 PolarHBondContact O-N 3.48Å; S351-A354 PolarHBondContact O-N 2.7Å; A354-F357 PolarHBondContact O-N 2.66Å; A354-H358 PolarHBondContact O-N 2.95Å; A354-H358 VanDerWaalsContact O-N 3.11Å
355	T	88.5	Confident	85.9	Confident	0 Å²	0	21.1 Å²	21.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-67	-36.4	175.2	53.2	0	0	0	0	113.7	L316 S351 F352 H353 H358 V359 A405 V408 L409	L316-T355 HydrophobicContact CD1-CG2 3.83Å; L316-T355 HydrophobicContact CD2-CG2 3.62Å; L316-T355 HydrophobicContact CG-CG2 4.41Å; S351-T355 WeakPolarHBondContact O-CG2 3.47Å; S351-T355 PolarHBondContact O-N 3.13Å; S351-T355 PolarHBondContact O-OG1 2.91Å; F352-T355 PolarHBondContact O-OG1 2.87Å; H353-T355 VanDerWaalsContact C-N 3.3Å; H353-T355 PolarHBondContact O-N 3.02Å; T355-H358 PolarHBondContact O-N 2.72Å; T355-V359 WeakPolarHBondContact O-CB 3.49Å; T355-V359 VanDerWaalsContact O-CG2 3.26Å; T355-V359 WeakPolarHBondContact O-CG2 2.97Å; T355-V359 PolarHBondContact O-N 3.35Å; T355-A405 HydrophobicContact CG2-CB 4.47Å; T355-V408 HydrophobicContact CG2-CB 3.8Å; T355-V408 HydrophobicContact CG2-CG1 3.51Å; T355-L409 WeakPolarHBondContact OG1-CA 3.47Å; T355-L409 WeakPolarHBondContact OG1-CD1 3.27Å
356	M	88	Confident	85.4	Confident	22 Å²	22	24 Å²	24	11%	0.108	12%	0.12	C	C	.	.	H	α-helix	trans	-63	-44.3	176.5	179	-173.1	73.1	0	0	111.1	F352 H353 V359 I360 L409 T495 F498 I502	F352-M356 VanDerWaalsContact O-CB 3.3Å; F352-M356 WeakPolarHBondContact O-CB 3.43Å; F352-M356 PolarHBondContact O-N 3.18Å; H353-M356 PolarHBondContact O-N 3.41Å; M356-V359 PolarHBondContact O-N 3.36Å; M356-I360 HydrophobicContact CG-CD1 3.75Å; M356-I360 HydrophobicContact CG-CG1 4.48Å; M356-I360 WeakPolarHBondContact O-CB 3.13Å; M356-I360 VanDerWaalsContact O-CG1 3.23Å; M356-I360 WeakPolarHBondContact O-CG1 3.46Å; M356-I360 PolarHBondContact O-N 3.37Å; M356-L409 HydrophobicContact CB-CD1 3.98Å; M356-T495 HydrophobicContact CE-CG2 3.95Å; M356-F498 HydrophobicContact CE-CB 3.49Å; M356-F498 VanDerWaalsContact CE-CB 3.49Å; M356-F498 HydrophobicContact CE-CD2 3.78Å; M356-F498 HydrophobicContact CE-CG 3.94Å; M356-F498 HydrophobicContact SD-CB 4.08Å; M356-F498 HydrophobicContact SD-CD2 3.95Å; M356-F498 HydrophobicContact SD-CG 4.07Å; M356-I502 HydrophobicContact CE-CD1 4.3Å; M356-I502 HydrophobicContact SD-CD1 4.36Å
357	F	84.6	Confident	85.3	Confident	2 Å²	2	31.6 Å²	31.6	1%	0.009	15%	0.153	C	C	.	.	H	α-helix	trans	-60.6	-45.7	174.4	174.6	-88.1	0	0	0	112	Y310 S312 H353 A354 I360 T361 I487 I491 H492 T495	Y310-F357 HydrophobicContact CD1-CE1 4.16Å; S312-F357 WeakPolarHBondContact OG-CD1 3.43Å; S312-F357 WeakPolarHBondContact OG-CE1 3.48Å; H353-F357 PolarHBondContact O-N 2.94Å; A354-F357 PolarHBondContact O-N 2.66Å; F357-I360 PolarHBondContact O-N 3.15Å; F357-T361 WeakPolarHBondContact O-CB 3.21Å; F357-T361 PolarHBondContact O-N 2.86Å; F357-T361 PolarHBondContact O-OG1 3.38Å; F357-I487 HydrophobicContact CZ-CG2 3.86Å; F357-I491 HydrophobicContact CD2-CG2 4.04Å; F357-I491 HydrophobicContact CE2-CG2 3.95Å; F357-H492 HydrophobicContact CE2-CB 3.93Å; F357-T495 HydrophobicContact CB-CG2 3.99Å; F357-T495 HydrophobicContact CD2-CG2 3.94Å; F357-T495 WeakPolarHBondContact CD2-OG1 3.27Å; F357-T495 HydrophobicContact CG-CG2 4.45Å
358	H	82.9	Confident	84.7	Confident	9 Å²	9	33.7 Å²	33.7	4%	0.042	16%	0.164	C	C	.	.	H	α-helix	trans	-58.2	-51.2	177.7	-176.6	87.8	0	0	0	111.5	E313 A354 T355 I360 T361 Y362 E401 A405	E313-H358 HydrophobicContact CG-CB 4.25Å; E313-H358 WeakPolarHBondContact CG-ND1 3.33Å; E313-H358 IonicContact OE1-CE1 3.1Å; E313-H358 IonicContact OE1-CG 3.76Å; E313-H358 IonicContact OE1-ND1 3.6Å; E313-H358 PolarHBondContact OE1-ND1 2.79Å; E313-H358 IonicContact OE2-CE1 3.63Å; E313-H358 IonicContact OE2-ND1 2.62Å; E313-H358 PolarHBondContact OE2-ND1 3.5Å; A354-H358 PolarHBondContact O-N 2.95Å; A354-H358 VanDerWaalsContact O-N 3.11Å; T355-H358 PolarHBondContact O-N 2.72Å; H358-I360 PolarHBondContact O-N 2.76Å; H358-T361 PolarHBondContact O-N 3.27Å; H358-Y362 WeakPolarHBondContact O-CB 3.21Å; H358-Y362 PolarHBondContact O-N 3.45Å; H358-E401 VanDerWaalsContact CE1-CD 3.49Å; H358-E401 IonicContact CE1-OE1 3.56Å; H358-A405 HydrophobicContact CB-CB 4.39Å; H358-A405 WeakPolarHBondContact CD2-CB 2.71Å
359	V	87.1	Confident	83.8	Confident	19 Å²	19	41.2 Å²	41.2	12%	0.115	20%	0.199	C	C	.	.	H	α-helix	trans	-63.9	-44.2	-178.6	172.8	0	0	0	0	111.6	T355 M356 T361 Y362 L363 A405 I406	T355-V359 WeakPolarHBondContact O-CB 3.49Å; T355-V359 VanDerWaalsContact O-CG2 3.26Å; T355-V359 WeakPolarHBondContact O-CG2 2.97Å; T355-V359 PolarHBondContact O-N 3.35Å; M356-V359 PolarHBondContact O-N 3.36Å; V359-T361 VanDerWaalsContact C-N 3.3Å; V359-T361 PolarHBondContact O-N 3.44Å; V359-Y362 PolarHBondContact O-N 3.32Å; V359-L363 HydrophobicContact CG1-CD1 4.04Å; V359-L363 HydrophobicContact CG1-CG 4.43Å; V359-L363 WeakPolarHBondContact O-CB 3.13Å; V359-L363 VanDerWaalsContact O-CG 3.26Å; V359-L363 WeakPolarHBondContact O-CG 2.89Å; V359-L363 PolarHBondContact O-N 2.94Å; V359-A405 HydrophobicContact CG2-CB 4.05Å; V359-I406 HydrophobicContact CG1-CG1 4.23Å; V359-I406 HydrophobicContact CG2-CG1 3.74Å
360	I	85.9	Confident	82.8	Confident	55 Å²	55	43.3 Å²	43.3	28%	0.282	21%	0.207	S	C	.	.	H	α-helix	trans	-63.2	-40.9	178	-67.8	169.5	0	0	0	110.5	M356 F357 H358 L363 Y364 I491 T495	M356-I360 HydrophobicContact CG-CD1 3.75Å; M356-I360 HydrophobicContact CG-CG1 4.48Å; M356-I360 WeakPolarHBondContact O-CB 3.13Å; M356-I360 VanDerWaalsContact O-CG1 3.23Å; M356-I360 WeakPolarHBondContact O-CG1 3.46Å; M356-I360 PolarHBondContact O-N 3.37Å; F357-I360 PolarHBondContact O-N 3.15Å; H358-I360 PolarHBondContact O-N 2.76Å; I360-L363 PolarHBondContact O-N 3.35Å; I360-Y364 WeakPolarHBondContact O-CB 3.3Å; I360-Y364 PolarHBondContact O-N 2.9Å; I360-I491 HydrophobicContact CB-CG2 4.3Å; I360-I491 HydrophobicContact CG2-CD1 4.5Å; I360-I491 HydrophobicContact CG2-CG1 4.46Å; I360-I491 HydrophobicContact CG2-CG2 3.69Å; I360-T495 HydrophobicContact CD1-CG2 3.93Å
361	T	80.6	Confident	81.6	Confident	0 Å²	0	45 Å²	45	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-67.7	-44.2	179.4	-53.1	0	0	0	0	111.7	Y310 F357 H358 V359 L363 Y364 L365 I487	Y310-T361 HydrophobicContact CD1-CG2 4.46Å; Y310-T361 HydrophobicContact CE1-CG2 3.38Å; F357-T361 WeakPolarHBondContact O-CB 3.21Å; F357-T361 PolarHBondContact O-N 2.86Å; F357-T361 PolarHBondContact O-OG1 3.38Å; H358-T361 PolarHBondContact O-N 3.27Å; V359-T361 VanDerWaalsContact C-N 3.3Å; V359-T361 PolarHBondContact O-N 3.44Å; T361-L363 VanDerWaalsContact C-N 3.34Å; T361-L363 PolarHBondContact O-N 3.47Å; T361-Y364 PolarHBondContact O-N 3.09Å; T361-L365 HydrophobicContact CG2-CD1 4.16Å; T361-L365 HydrophobicContact CG2-CG 4.33Å; T361-L365 WeakPolarHBondContact O-CG 3.24Å; T361-L365 PolarHBondContact O-N 3.02Å; T361-I487 HydrophobicContact CG2-CB 4.44Å; T361-I487 HydrophobicContact CG2-CD1 3.5Å; T361-I487 VanDerWaalsContact CG2-CD1 3.5Å; T361-I487 HydrophobicContact CG2-CG1 3.61Å; T361-I487 HydrophobicContact CG2-CG2 3.96Å
362	Y	81.1	Confident	79.9	Confident	45 Å²	45	46.6 Å²	46.6	18%	0.176	23%	0.231	C	C	.	.	H	α-helix	trans	-57.5	-45.9	174.3	176.8	-93.9	0	0	0	112	H358 V359 Y364 L365 T366 F371 F399 A402	H358-Y362 WeakPolarHBondContact O-CB 3.21Å; H358-Y362 PolarHBondContact O-N 3.45Å; V359-Y362 PolarHBondContact O-N 3.32Å; Y362-Y364 PolarHBondContact O-N 3.47Å; Y362-L365 PolarHBondContact O-N 2.87Å; Y362-T366 WeakPolarHBondContact CE1-OG1 3.26Å; Y362-T366 WeakPolarHBondContact O-CB 3.3Å; Y362-T366 PolarHBondContact O-N 3.36Å; Y362-T366 PolarHBondContact O-OG1 2.94Å; Y362-F371 AromaticContact CD2-CE2 3.98Å; Y362-F371 HydrophobicContact CD2-CE2 3.98Å; Y362-F371 AromaticContact CD2-CZ 3.82Å; Y362-F371 HydrophobicContact CD2-CZ 3.82Å; Y362-F371 AromaticContact CE2-CE2 3.97Å; Y362-F371 HydrophobicContact CE2-CE2 3.97Å; Y362-F371 HydrophobicContact CE2-CZ 4.01Å; Y362-F399 WeakPolarHBondContact OH-CD2 3.38Å; Y362-A402 HydrophobicContact CD1-CB 3.66Å; Y362-A402 HydrophobicContact CD2-CB 3.52Å; Y362-A402 HydrophobicContact CE1-CB 3.93Å; Y362-A402 HydrophobicContact CE2-CB 3.79Å; Y362-A402 HydrophobicContact CG-CB 3.46Å; Y362-A402 VanDerWaalsContact CG-CB 3.46Å
363	L	85.4	Confident	78.1	Confident	106 Å²	106	48.4 Å²	48.4	56%	0.555	25%	0.249	S	C	*	.	H	α-helix	trans	-62.8	-41.3	177.2	-72	173.4	0	0	0	112	V359 I360 T361 K367	V359-L363 HydrophobicContact CG1-CD1 4.04Å; V359-L363 HydrophobicContact CG1-CG 4.43Å; V359-L363 WeakPolarHBondContact O-CB 3.13Å; V359-L363 VanDerWaalsContact O-CG 3.26Å; V359-L363 WeakPolarHBondContact O-CG 2.89Å; V359-L363 PolarHBondContact O-N 2.94Å; I360-L363 PolarHBondContact O-N 3.35Å; T361-L363 VanDerWaalsContact C-N 3.34Å; T361-L363 PolarHBondContact O-N 3.47Å; L363-K367 VanDerWaalsContact O-CB 3.23Å; L363-K367 WeakPolarHBondContact O-CB 3.38Å; L363-K367 PolarHBondContact O-N 3.47Å
364	Y	82.6	Confident	76.6	Confident	50 Å²	50	54.6 Å²	54.6	20%	0.196	28%	0.278	C	S	.	.	H	α-helix	trans	-62.9	-46.7	175.8	172.1	-97.8	0	0	0	111.6	I360 T361 Y362 K367 N368 Y370 P483 V486 I487 I491	I360-Y364 WeakPolarHBondContact O-CB 3.3Å; I360-Y364 PolarHBondContact O-N 2.9Å; T361-Y364 PolarHBondContact O-N 3.09Å; Y362-Y364 PolarHBondContact O-N 3.47Å; Y364-K367 PolarHBondContact O-N 2.66Å; Y364-N368 VanDerWaalsContact CD2-ND2 3.28Å; Y364-N368 WeakPolarHBondContact CD2-ND2 3.46Å; Y364-N368 WeakPolarHBondContact CE2-ND2 3.36Å; Y364-N368 PolarHBondContact O-N 3.29Å; Y364-N368 PolarHBondContact O-ND2 2.93Å; Y364-Y370 HydrophobicContact CE1-CD2 4.4Å; Y364-Y370 AromaticContact CE1-CE2 3.99Å; Y364-Y370 HydrophobicContact CE1-CE2 3.99Å; Y364-P483 HydrophobicContact CE1-CB 4.41Å; Y364-V486 HydrophobicContact CD2-CG1 4.3Å; Y364-V486 HydrophobicContact CE1-CB 4.11Å; Y364-V486 HydrophobicContact CE1-CG1 4.01Å; Y364-V486 HydrophobicContact CE2-CB 4.4Å; Y364-V486 HydrophobicContact CE2-CG1 3.63Å; Y364-V486 VanDerWaalsContact CZ-CG1 3.48Å; Y364-V486 WeakPolarHBondContact OH-CB 3.18Å; Y364-V486 WeakPolarHBondContact OH-CG2 3.25Å; Y364-I487 HydrophobicContact CD1-CG1 4.3Å; Y364-I487 HydrophobicContact CE1-CG1 4.48Å; Y364-I491 HydrophobicContact CD1-CD1 3.87Å; Y364-I491 HydrophobicContact CD2-CD1 4.28Å; Y364-I491 HydrophobicContact CG-CD1 3.65Å
365	L	77.2	Confident	75.2	Confident	9 Å²	9	55.2 Å²	55.2	5%	0.047	28%	0.28	C	S	.	.	H	α-helix	trans	-65.6	-40.8	179.7	-72.2	177.8	0	0	0	112.4	Y310 T361 Y362 N368 E369 Y370 F371 P483 I487	Y310-L365 WeakPolarHBondContact OH-CD1 3.35Å; T361-L365 HydrophobicContact CG2-CD1 4.16Å; T361-L365 HydrophobicContact CG2-CG 4.33Å; T361-L365 WeakPolarHBondContact O-CG 3.24Å; T361-L365 PolarHBondContact O-N 3.02Å; Y362-L365 PolarHBondContact O-N 2.87Å; L365-N368 PolarHBondContact O-N 3.33Å; L365-E369 PolarHBondContact O-N 2.99Å; L365-Y370 HydrophobicContact CD2-CD2 3.61Å; L365-Y370 HydrophobicContact CD2-CG 3.9Å; L365-Y370 PolarHBondContact O-N 3.47Å; L365-F371 HydrophobicContact CB-CD2 4.12Å; L365-F371 HydrophobicContact CB-CE2 3.41Å; L365-F371 VanDerWaalsContact CB-CE2 3.41Å; L365-F371 HydrophobicContact CB-CZ 3.73Å; L365-F371 HydrophobicContact CD1-CE1 4.48Å; L365-F371 HydrophobicContact CD1-CE2 4.46Å; L365-F371 HydrophobicContact CD1-CZ 3.93Å; L365-P483 HydrophobicContact CD2-CB 4.19Å; L365-I487 HydrophobicContact CD1-CD1 4.25Å; L365-I487 HydrophobicContact CD2-CD1 3.88Å; L365-I487 HydrophobicContact CG-CD1 4.15Å
366	T	79.2	Confident	73.6	Confident	63 Å²	63	55.9 Å²	55.9	39%	0.387	28%	0.284	S	S	.	.	H	α-helix	trans	-63.2	-46.2	176.4	-55.8	0	0	0	0	111.1	Y362 N368 E369 F371	Y362-T366 WeakPolarHBondContact CE1-OG1 3.26Å; Y362-T366 WeakPolarHBondContact O-CB 3.3Å; Y362-T366 PolarHBondContact O-N 3.36Å; Y362-T366 PolarHBondContact O-OG1 2.94Å; T366-N368 VanDerWaalsContact C-N 3.27Å; T366-N368 PolarHBondContact O-N 3.14Å; T366-E369 PolarHBondContact O-N 2.86Å; T366-E369 VanDerWaalsContact O-N 3.16Å; T366-F371 WeakPolarHBondContact OG1-CE2 3.45Å
367	K	82.7	Confident	72.1	Confident	178 Å²	178	60.3 Å²	60.3	77%	0.774	31%	0.309	S	S	*	.	H	α-helix	trans	-62.8	-33.4	-177.9	-178.1	177.5	177.7	-177.6	0	113.1	L363 Y364	L363-K367 VanDerWaalsContact O-CB 3.23Å; L363-K367 WeakPolarHBondContact O-CB 3.38Å; L363-K367 PolarHBondContact O-N 3.47Å; Y364-K367 PolarHBondContact O-N 2.66Å
368	N	76.3	Confident	70.8	Confident	71 Å²	71	64.3 Å²	64.3	38%	0.38	33%	0.33	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98.7	16.2	-179.7	-61.2	-68.4	0	0	0	112.6	Y364 L365 T366 Y370	Y364-N368 VanDerWaalsContact CD2-ND2 3.28Å; Y364-N368 WeakPolarHBondContact CD2-ND2 3.46Å; Y364-N368 WeakPolarHBondContact CE2-ND2 3.36Å; Y364-N368 PolarHBondContact O-N 3.29Å; Y364-N368 PolarHBondContact O-ND2 2.93Å; L365-N368 PolarHBondContact O-N 3.33Å; T366-N368 VanDerWaalsContact C-N 3.27Å; T366-N368 PolarHBondContact O-N 3.14Å; N368-Y370 HydrophobicContact CB-CD2 3.5Å; N368-Y370 VanDerWaalsContact CB-CD2 3.5Å; N368-Y370 HydrophobicContact CB-CE2 3.28Å; N368-Y370 HydrophobicContact CB-CG 4.47Å; N368-Y370 PolarHBondContact O-N 2.85Å
369	E	72	Confident	69.4	Low	158 Å²	158	66 Å²	66	74%	0.738	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.6	23.8	175	-56.5	-175.6	168.1	0	0	114.8	L365 T366 F371 G372	L365-E369 PolarHBondContact O-N 2.99Å; T366-E369 PolarHBondContact O-N 2.86Å; T366-E369 VanDerWaalsContact O-N 3.16Å; E369-F371 PolarHBondContact O-N 2.95Å; E369-F371 VanDerWaalsContact O-N 3.08Å; E369-G372 PolarHBondContact O-N 2.77Å
370	Y	67.8	Low	67.8	Low	49 Å²	49	68.1 Å²	68.1	19%	0.192	35%	0.345	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.6	-7.6	178	-70.8	-60.5	0	0	0	112.8	Y364 L365 N368 G372 L375 L378 E481 P483	Y364-Y370 HydrophobicContact CE1-CD2 4.4Å; Y364-Y370 AromaticContact CE1-CE2 3.99Å; Y364-Y370 HydrophobicContact CE1-CE2 3.99Å; L365-Y370 HydrophobicContact CD2-CD2 3.61Å; L365-Y370 HydrophobicContact CD2-CG 3.9Å; L365-Y370 PolarHBondContact O-N 3.47Å; N368-Y370 HydrophobicContact CB-CD2 3.5Å; N368-Y370 VanDerWaalsContact CB-CD2 3.5Å; N368-Y370 HydrophobicContact CB-CE2 3.28Å; N368-Y370 HydrophobicContact CB-CG 4.47Å; N368-Y370 PolarHBondContact O-N 2.85Å; Y370-G372 VanDerWaalsContact C-N 3.29Å; Y370-L375 VanDerWaalsContact O-CB 3.3Å; Y370-L375 WeakPolarHBondContact O-CB 3.35Å; Y370-L375 WeakPolarHBondContact O-CD1 3.35Å; Y370-L375 WeakPolarHBondContact O-CG 3.45Å; Y370-L378 HydrophobicContact CD1-CD2 4.34Å; Y370-L378 HydrophobicContact CE1-CD2 4.12Å; Y370-E481 PolarHBondContact OH-O 3.37Å; Y370-P483 HydrophobicContact CD1-CB 4.24Å; Y370-P483 HydrophobicContact CD1-CG 3.96Å; Y370-P483 HydrophobicContact CD2-CB 3.98Å; Y370-P483 HydrophobicContact CE1-CB 3.97Å; Y370-P483 HydrophobicContact CE1-CG 3.6Å; Y370-P483 HydrophobicContact CE2-CB 3.67Å; Y370-P483 HydrophobicContact CE2-CG 4.25Å; Y370-P483 HydrophobicContact CG-CB 4.26Å; Y370-P483 HydrophobicContact CG-CG 4.46Å
371	F	62.2	Low	65.9	Low	42 Å²	42	76.3 Å²	76.3	18%	0.184	37%	0.374	C	S	.	.	T	Hydrogen-bonded Turn	trans	-86.8	4.3	170.2	-65.3	-70.2	0	0	0	113.6	H306 Y362 L365 T366 E369 H398	H306-F371 AromaticContact CE1-CE1 3.92Å; Y362-F371 AromaticContact CD2-CE2 3.98Å; Y362-F371 HydrophobicContact CD2-CE2 3.98Å; Y362-F371 AromaticContact CD2-CZ 3.82Å; Y362-F371 HydrophobicContact CD2-CZ 3.82Å; Y362-F371 AromaticContact CE2-CE2 3.97Å; Y362-F371 HydrophobicContact CE2-CE2 3.97Å; Y362-F371 HydrophobicContact CE2-CZ 4.01Å; L365-F371 HydrophobicContact CB-CD2 4.12Å; L365-F371 HydrophobicContact CB-CE2 3.41Å; L365-F371 VanDerWaalsContact CB-CE2 3.41Å; L365-F371 HydrophobicContact CB-CZ 3.73Å; L365-F371 HydrophobicContact CD1-CE1 4.48Å; L365-F371 HydrophobicContact CD1-CE2 4.46Å; L365-F371 HydrophobicContact CD1-CZ 3.93Å; T366-F371 WeakPolarHBondContact OG1-CE2 3.45Å; E369-F371 PolarHBondContact O-N 2.95Å; E369-F371 VanDerWaalsContact O-N 3.08Å; F371-H398 HydrophobicContact CE1-CB 4.29Å
372	G	53.2	Low	64.4	Low	34 Å²	34	79.8 Å²	79.8	35%	0.351	41%	0.409	S	S	.	.	S	Bend	trans	-80.2	173.5	174.5	0	0	0	0	0	113.7	E369 Y370 Q374 L375	E369-G372 PolarHBondContact O-N 2.77Å; Y370-G372 VanDerWaalsContact C-N 3.29Å; G372-Q374 PolarHBondContact O-N 3.48Å; G372-L375 PolarHBondContact O-N 3.38Å; G372-L375 VanDerWaalsContact O-N 3.15Å
373	S	52.5	Low	62.9	Low	78 Å²	78	86 Å²	86	55%	0.545	43%	0.433	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.9	-7.1	-178.6	59.9	0	0	0	0	115.2
374	Q	53.8	Low	61.2	Low	151 Å²	151	90.1 Å²	90.1	71%	0.706	45%	0.448	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.9	-17.4	-179.4	-61.8	-179.4	3.4	0	0	113.1	G372 C376 D377 L378	G372-Q374 PolarHBondContact O-N 3.48Å; Q374-C376 VanDerWaalsContact C-N 3.33Å; Q374-C376 PolarHBondContact O-N 2.87Å; Q374-D377 PolarHBondContact O-N 3.34Å; Q374-L378 WeakPolarHBondContact O-CB 3.3Å; Q374-L378 PolarHBondContact O-N 2.88Å
375	L	56.6	Low	59.7	Low	19 Å²	19	96.5 Å²	96.5	10%	0.099	48%	0.477	C	S	.	.	H	α-helix	trans	-65.8	-37.5	-174.7	-165.9	77.3	0	0	0	111.8	F305 H306 Y370 G372 L378 F379	F305-L375 HydrophobicContact CD1-CD2 3.45Å; F305-L375 VanDerWaalsContact CD1-CD2 3.45Å; F305-L375 HydrophobicContact CD1-CG 3.84Å; F305-L375 HydrophobicContact CE1-CD1 4.08Å; F305-L375 HydrophobicContact CE1-CD2 3.59Å; F305-L375 HydrophobicContact CE1-CG 3.55Å; H306-L375 WeakPolarHBondContact CE1-CD2 3.43Å; Y370-L375 VanDerWaalsContact O-CB 3.3Å; Y370-L375 WeakPolarHBondContact O-CB 3.35Å; Y370-L375 WeakPolarHBondContact O-CD1 3.35Å; Y370-L375 WeakPolarHBondContact O-CG 3.45Å; G372-L375 PolarHBondContact O-N 3.38Å; G372-L375 VanDerWaalsContact O-N 3.15Å; L375-L378 PolarHBondContact O-N 3.27Å; L375-F379 HydrophobicContact CD1-CD2 4.12Å; L375-F379 HydrophobicContact CD1-CE2 3.49Å; L375-F379 VanDerWaalsContact CD1-CE2 3.49Å; L375-F379 HydrophobicContact CD1-CZ 4.43Å; L375-F379 HydrophobicContact CG-CD2 4.33Å; L375-F379 HydrophobicContact CG-CE2 4.17Å; L375-F379 VanDerWaalsContact O-CD2 3.29Å; L375-F379 WeakPolarHBondContact O-CD2 2.95Å; L375-F379 PolarHBondContact O-N 3.49Å
376	C	54.5	Low	58.7	Low	13 Å²	13	98.1 Å²	98.1	9%	0.088	49%	0.489	C	S	.	.	H	α-helix	trans	-70.3	-37.4	-179.8	-115.2	0	0	0	0	112.8	Q374 F380 C386 E391	Q374-C376 VanDerWaalsContact C-N 3.33Å; Q374-C376 PolarHBondContact O-N 2.87Å; C376-F380 PolarHBondContact O-N 2.94Å; C376-C386 HydrophobicContact CB-CB 3.27Å; C376-C386 WeakPolarHBondContact CB-SG 3.24Å; C376-C386 WeakPolarHBondContact SG-CB 3.48Å; C376-C386 CovalentContact SG-SG 1.98Å; C376-C386 PolarHBondContact SG-SG 3.49Å; C376-E391 WeakPolarHBondContact CB-OE1 3.37Å
377	D	56.4	Low	57.6	Low	116 Å²	116	100.2 Å²	100.2	62%	0.62	50%	0.497	S	S	*	.	H	α-helix	trans	-68.6	-35.9	174.1	-75.2	-19.6	0	0	0	112.2	Q374 F379	Q374-D377 PolarHBondContact O-N 3.34Å; D377-F379 VanDerWaalsContact C-N 3.28Å; D377-F379 PolarHBondContact O-N 3.26Å
378	L	56.7	Low	56.3	Low	85 Å²	85	99.9 Å²	99.9	45%	0.445	49%	0.493	S	S	.	.	H	α-helix	trans	-66.4	-28.9	-177.2	-166.8	73.2	0	0	0	112.9	Y370 Q374 L375 P483	Y370-L378 HydrophobicContact CD1-CD2 4.34Å; Y370-L378 HydrophobicContact CE1-CD2 4.12Å; Q374-L378 WeakPolarHBondContact O-CB 3.3Å; Q374-L378 PolarHBondContact O-N 2.88Å; L375-L378 PolarHBondContact O-N 3.27Å; L378-P483 HydrophobicContact CD2-CG 3.84Å
379	F	53.9	Low	55.3	Low	46 Å²	46	106.9 Å²	106.9	20%	0.202	51%	0.514	C	S	.	.	H	α-helix	trans	-120.4	-16.3	-172.8	-68.7	-102.8	0	0	0	115.4	F305 F309 L375 D377 H482 P483 L484	F305-F379 HydrophobicContact CD2-CB 4.49Å; F305-F379 HydrophobicContact CE1-CB 4.12Å; F305-F379 HydrophobicContact CE1-CD1 4.39Å; F305-F379 AromaticContact CE1-CD2 3.53Å; F305-F379 HydrophobicContact CE1-CD2 3.53Å; F305-F379 HydrophobicContact CE1-CE1 4.46Å; F305-F379 AromaticContact CE1-CE2 3.76Å; F305-F379 HydrophobicContact CE1-CE2 3.76Å; F305-F379 AromaticContact CE1-CG 3.88Å; F305-F379 HydrophobicContact CE1-CG 3.88Å; F305-F379 HydrophobicContact CE1-CZ 4.2Å; F305-F379 HydrophobicContact CE2-CB 3.27Å; F305-F379 HydrophobicContact CE2-CD1 4.1Å; F305-F379 HydrophobicContact CE2-CD2 4.26Å; F305-F379 AromaticContact CE2-CG 3.75Å; F305-F379 HydrophobicContact CE2-CG 3.75Å; F305-F379 HydrophobicContact CZ-CB 3.07Å; F305-F379 AromaticContact CZ-CD1 3.41Å; F305-F379 HydrophobicContact CZ-CD1 3.41Å; F305-F379 VanDerWaalsContact CZ-CD1 3.41Å; F305-F379 AromaticContact CZ-CD2 3.18Å; F305-F379 HydrophobicContact CZ-CD2 3.18Å; F305-F379 AromaticContact CZ-CE1 3.79Å; F305-F379 HydrophobicContact CZ-CE1 3.79Å; F305-F379 AromaticContact CZ-CE2 3.7Å; F305-F379 HydrophobicContact CZ-CE2 3.7Å; F305-F379 AromaticContact CZ-CG 3.01Å; F305-F379 HydrophobicContact CZ-CG 3.01Å; F305-F379 AromaticContact CZ-CZ 3.96Å; F305-F379 HydrophobicContact CZ-CZ 3.96Å; F309-F379 HydrophobicContact CD1-CE1 4.35Å; F309-F379 AromaticContact CE1-CD1 3.94Å; F309-F379 HydrophobicContact CE1-CD1 3.94Å; F309-F379 AromaticContact CE1-CE1 3.46Å; F309-F379 HydrophobicContact CE1-CE1 3.46Å; F309-F379 VanDerWaalsContact CE1-CE1 3.46Å; F309-F379 HydrophobicContact CE1-CZ 4.35Å; F309-F379 HydrophobicContact CE2-CD1 4.4Å; F309-F379 HydrophobicContact CE2-CE1 4.04Å; F309-F379 HydrophobicContact CE2-CZ 4.38Å; F309-F379 AromaticContact CZ-CD1 3.49Å; F309-F379 HydrophobicContact CZ-CD1 3.49Å; F309-F379 VanDerWaalsContact CZ-CD1 3.49Å; F309-F379 AromaticContact CZ-CE1 3.28Å; F309-F379 HydrophobicContact CZ-CE1 3.28Å; F309-F379 HydrophobicContact CZ-CG 4.29Å; F309-F379 HydrophobicContact CZ-CZ 4.04Å; L375-F379 HydrophobicContact CD1-CD2 4.12Å; L375-F379 HydrophobicContact CD1-CE2 3.49Å; L375-F379 VanDerWaalsContact CD1-CE2 3.49Å; L375-F379 HydrophobicContact CD1-CZ 4.43Å; L375-F379 HydrophobicContact CG-CD2 4.33Å; L375-F379 HydrophobicContact CG-CE2 4.17Å; L375-F379 VanDerWaalsContact O-CD2 3.29Å; L375-F379 WeakPolarHBondContact O-CD2 2.95Å; L375-F379 PolarHBondContact O-N 3.49Å; D377-F379 VanDerWaalsContact C-N 3.28Å; D377-F379 PolarHBondContact O-N 3.26Å; F379-H482 AromaticContact CE1-CE1 3.73Å; F379-H482 AromaticContact CZ-CE1 3.96Å; F379-P483 HydrophobicContact CE2-CG 4.26Å; F379-P483 HydrophobicContact CZ-CG 3.98Å; F379-L484 HydrophobicContact CD1-CD1 4.05Å; F379-L484 HydrophobicContact CD1-CG 4.49Å; F379-L484 HydrophobicContact CE1-CD1 3.46Å; F379-L484 VanDerWaalsContact CE1-CD1 3.46Å; F379-L484 HydrophobicContact CE1-CD2 3.96Å; F379-L484 HydrophobicContact CE1-CG 3.45Å; F379-L484 VanDerWaalsContact CE1-CG 3.45Å; F379-L484 HydrophobicContact CZ-CD1 4.46Å; F379-L484 HydrophobicContact CZ-CD2 4.49Å; F379-L484 HydrophobicContact CZ-CG 4.02Å
380	F	52.3	Low	54.6	Low	62 Å²	62	102 Å²	102	27%	0.272	50%	0.495	S	S	.	.			trans	-131.6	53.5	176.5	-64.4	-59.2	0	0	0	112.1	F305 C376 G382 R383	F305-F380 HydrophobicContact CB-CE2 4.42Å; F305-F380 AromaticContact CD2-CD2 3.76Å; F305-F380 HydrophobicContact CD2-CD2 3.76Å; F305-F380 AromaticContact CD2-CE2 3.09Å; F305-F380 HydrophobicContact CD2-CE2 3.09Å; F305-F380 AromaticContact CD2-CZ 3.67Å; F305-F380 HydrophobicContact CD2-CZ 3.67Å; F305-F380 AromaticContact CE2-CD2 4Å; F305-F380 HydrophobicContact CE2-CD2 4Å; F305-F380 AromaticContact CE2-CE2 3.59Å; F305-F380 HydrophobicContact CE2-CE2 3.59Å; F305-F380 AromaticContact CE2-CZ 3.95Å; F305-F380 HydrophobicContact CE2-CZ 3.95Å; F305-F380 HydrophobicContact CG-CE2 4.08Å; C376-F380 PolarHBondContact O-N 2.94Å; F380-G382 PolarHBondContact O-N 2.83Å; F380-R383 HydrophobicContact CB-CB 4.03Å; F380-R383 HydrophobicContact CB-CG 4.31Å; F380-R383 HydrophobicContact CD1-CG 4.49Å; F380-R383 PolarHBondContact O-N 3.37Å
381	Y	47.1	Very low	54.4	Low	228 Å²	228	101.8 Å²	101.8	89%	0.894	50%	0.495	S	S	*	.	T	Hydrogen-bonded Turn	trans	-44.8	107.6	168.1	-162	-92.9	0	0	0	110.1
382	G	50	Low	54.6	Low	72 Å²	72	105 Å²	105	74%	0.742	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	88.5	10.1	178.7	0	0	0	0	0	118.5	F380	F380-G382 PolarHBondContact O-N 2.83Å
383	R	49	Very low	55.3	Low	177 Å²	177	106.1 Å²	106.1	67%	0.668	52%	0.517	S	S	*	.			trans	-97.3	116.2	167.8	-66	-168.9	176.1	179.8	-0.6	112.3	F380 K385	F380-R383 HydrophobicContact CB-CB 4.03Å; F380-R383 HydrophobicContact CB-CG 4.31Å; F380-R383 HydrophobicContact CD1-CG 4.49Å; F380-R383 PolarHBondContact O-N 3.37Å; R383-K385 PolarHBondContact O-N 2.9Å
384	H	49.3	Very low	56	Low	191 Å²	191	102.5 Å²	102.5	88%	0.884	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	12.5	179.2	-76.2	-71.2	0	0	0	117.8
385	K	52	Low	56.8	Low	185 Å²	185	97.5 Å²	97.5	80%	0.804	47%	0.474	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.4	3.4	-170.1	-71.1	-169.2	177.1	-176.2	0	115.7	R383 N387	R383-K385 PolarHBondContact O-N 2.9Å; K385-N387 VanDerWaalsContact C-N 3.35Å; K385-N387 PolarHBondContact O-N 2.88Å
386	C	55	Low	57.7	Low	43 Å²	43	100.3 Å²	100.3	29%	0.291	49%	0.488	S	S	.	.			trans	-83.9	76.2	177	-69	0	0	0	0	111.4	C376	C376-C386 HydrophobicContact CB-CB 3.27Å; C376-C386 WeakPolarHBondContact CB-SG 3.24Å; C376-C386 WeakPolarHBondContact SG-CB 3.48Å; C376-C386 CovalentContact SG-SG 1.98Å; C376-C386 PolarHBondContact SG-SG 3.49Å
387	N	55.9	Low	58.7	Low	106 Å²	106	101.3 Å²	101.3	57%	0.567	49%	0.492	S	S	*	.			trans	-81.3	133.7	172.8	-76.9	-24.8	0	0	0	109.5	K385 R389 V390 E391	K385-N387 VanDerWaalsContact C-N 3.35Å; K385-N387 PolarHBondContact O-N 2.88Å; N387-R389 PolarHBondContact O-N 2.99Å; N387-V390 HydrophobicContact CB-CG2 4.32Å; N387-V390 WeakPolarHBondContact O-CA 3.28Å; N387-V390 WeakPolarHBondContact O-CB 3.37Å; N387-V390 PolarHBondContact O-N 3.22Å; N387-E391 PolarHBondContact O-N 3.25Å
388	Y	56.7	Low	59.6	Low	172 Å²	172	96.2 Å²	96.2	68%	0.675	47%	0.465	S	S	*	.	H	α-helix	trans	-45.4	-32.7	175.2	-179.8	-101	0	0	0	114.3	V390 E391 H392	Y388-V390 PolarHBondContact O-N 2.83Å; Y388-E391 PolarHBondContact O-N 2.82Å; Y388-H392 PolarHBondContact O-N 3.25Å
389	R	54.5	Low	60.9	Low	217 Å²	217	97.5 Å²	97.5	82%	0.819	47%	0.467	S	S	*	.	H	α-helix	trans	-64.5	-36.1	175	-73.5	-171.2	-176.7	-178.8	1.8	113.7	N387 A393	N387-R389 PolarHBondContact O-N 2.99Å; R389-A393 WeakPolarHBondContact O-CB 3.47Å; R389-A393 PolarHBondContact O-N 3.47Å; R389-A393 VanDerWaalsContact O-N 3.11Å
390	V	58	Low	62.3	Low	56 Å²	56	101.2 Å²	101.2	34%	0.339	48%	0.483	S	S	.	.	H	α-helix	trans	-71.4	-38.6	177.8	-179.9	0	0	0	0	109.9	T304 N387 Y388 G394	T304-V390 HydrophobicContact CG2-CG1 4.34Å; N387-V390 HydrophobicContact CB-CG2 4.32Å; N387-V390 WeakPolarHBondContact O-CA 3.28Å; N387-V390 WeakPolarHBondContact O-CB 3.37Å; N387-V390 PolarHBondContact O-N 3.22Å; Y388-V390 PolarHBondContact O-N 2.83Å; V390-G394 PolarHBondContact O-N 3.21Å
391	E	63.2	Low	63.9	Low	45 Å²	45	98.5 Å²	98.5	21%	0.21	47%	0.471	C	S	.	.	H	α-helix	trans	-65	-46.8	176.4	-62.9	179.2	164.8	0	0	111.9	C376 N387 Y388 G394 S395	C376-E391 WeakPolarHBondContact CB-OE1 3.37Å; N387-E391 PolarHBondContact O-N 3.25Å; Y388-E391 PolarHBondContact O-N 2.82Å; E391-G394 PolarHBondContact O-N 3.35Å; E391-S395 WeakPolarHBondContact O-CB 3.42Å; E391-S395 PolarHBondContact O-N 2.86Å
392	H	66.3	Low	65.7	Low	108 Å²	108	87.7 Å²	87.7	50%	0.5	43%	0.43	S	S	.	.	H	α-helix	trans	-66.2	-43.5	179.4	-173.1	-84.8	0	0	0	112.3	Y388 I396	Y388-H392 PolarHBondContact O-N 3.25Å; H392-I396 WeakPolarHBondContact CE1-CD1 3.38Å; H392-I396 WeakPolarHBondContact O-CG1 3.47Å; H392-I396 PolarHBondContact O-N 3.16Å; H392-I396 VanDerWaalsContact O-N 3.15Å
393	A	67.2	Low	67.6	Low	58 Å²	58	87.4 Å²	87.4	48%	0.479	41%	0.414	S	S	.	.	H	α-helix	trans	-65.2	-41.8	176	0	0	0	0	0	111.9	R389 L397	R389-A393 WeakPolarHBondContact O-CB 3.47Å; R389-A393 PolarHBondContact O-N 3.47Å; R389-A393 VanDerWaalsContact O-N 3.11Å; A393-L397 WeakPolarHBondContact O-CB 3.47Å; A393-L397 PolarHBondContact O-N 2.99Å
394	G	67.6	Low	69.6	Low	3 Å²	3	80.3 Å²	80.3	3%	0.031	39%	0.389	C	S	.	.	H	α-helix	trans	-62	-46.1	175.9	0	0	0	0	0	112.4	V390 E391 I396 L397 H398	V390-G394 PolarHBondContact O-N 3.21Å; E391-G394 PolarHBondContact O-N 3.35Å; G394-I396 PolarHBondContact O-N 3.06Å; G394-L397 PolarHBondContact O-N 3.14Å; G394-H398 PolarHBondContact O-CD2 2.95Å; G394-H398 PolarHBondContact O-N 3Å
395	S	69.7	Low	71.5	Confident	46 Å²	46	71.2 Å²	71.2	32%	0.322	35%	0.347	S	S	.	.	H	α-helix	trans	-60.3	-45	178.1	-178.3	0	0	0	0	112.6	E391 L397 H398 F399	E391-S395 WeakPolarHBondContact O-CB 3.42Å; E391-S395 PolarHBondContact O-N 2.86Å; S395-L397 VanDerWaalsContact C-N 3.35Å; S395-L397 PolarHBondContact O-N 3.08Å; S395-H398 PolarHBondContact O-N 3.1Å; S395-F399 PolarHBondContact O-N 3.48Å
396	I	76.4	Confident	73.4	Confident	77 Å²	77	66.2 Å²	66.2	40%	0.395	33%	0.328	S	S	.	.	H	α-helix	trans	-61	-45.2	174.7	-71.3	175.4	0	0	0	111	H392 G394 H398 F399 F400	H392-I396 WeakPolarHBondContact CE1-CD1 3.38Å; H392-I396 WeakPolarHBondContact O-CG1 3.47Å; H392-I396 PolarHBondContact O-N 3.16Å; H392-I396 VanDerWaalsContact O-N 3.15Å; G394-I396 PolarHBondContact O-N 3.06Å; I396-H398 PolarHBondContact O-N 2.97Å; I396-F399 WeakPolarHBondContact O-CB 3.22Å; I396-F399 PolarHBondContact O-N 3.04Å; I396-F400 HydrophobicContact CG2-CD2 3.72Å; I396-F400 HydrophobicContact CG2-CE2 3.48Å; I396-F400 VanDerWaalsContact CG2-CE2 3.48Å; I396-F400 WeakPolarHBondContact O-CD2 3.38Å; I396-F400 PolarHBondContact O-N 3.25Å
397	L	76.4	Confident	75.2	Confident	35 Å²	35	66.4 Å²	66.4	18%	0.183	33%	0.332	C	S	.	.	H	α-helix	trans	-63.3	-42	-179.5	-172.5	58.1	0	0	0	111.5	I295 V298 N299 A393 G394 S395 F399 F400 E401	I295-L397 HydrophobicContact CB-CD1 4.49Å; I295-L397 HydrophobicContact CG1-CD1 4.03Å; I295-L397 HydrophobicContact CG2-CD1 3.99Å; I295-L397 HydrophobicContact CG2-CD2 4.3Å; I295-L397 HydrophobicContact CG2-CG 3.96Å; V298-L397 HydrophobicContact CG1-CD2 4.02Å; N299-L397 WeakPolarHBondContact OD1-CD2 3.36Å; A393-L397 WeakPolarHBondContact O-CB 3.47Å; A393-L397 PolarHBondContact O-N 2.99Å; G394-L397 PolarHBondContact O-N 3.14Å; S395-L397 VanDerWaalsContact C-N 3.35Å; S395-L397 PolarHBondContact O-N 3.08Å; L397-F399 PolarHBondContact O-N 3.37Å; L397-F400 PolarHBondContact O-N 3.45Å; L397-E401 WeakPolarHBondContact O-CB 3.29Å; L397-E401 PolarHBondContact O-N 3.46Å
398	H	74.7	Confident	77	Confident	9 Å²	9	61.3 Å²	61.3	4%	0.042	31%	0.305	C	S	.	.	H	α-helix	trans	-66.4	-33.9	174.6	-73.9	-54.1	0	0	0	113.3	H306 F371 G394 S395 I396 E401 A402	H306-H398 WeakPolarHBondContact CB-NE2 3.48Å; H306-H398 AromaticContact CD2-CD2 3.41Å; H306-H398 PolarHBondContact CD2-CD2 3.48Å; H306-H398 VanDerWaalsContact CD2-CD2 3.41Å; H306-H398 AromaticContact CD2-CE1 3.87Å; H306-H398 AromaticContact CD2-NE2 2.86Å; H306-H398 PolarHBondContact CD2-NE2 3.41Å; H306-H398 AromaticContact CG-CD2 3.93Å; H306-H398 AromaticContact CG-CE1 3.72Å; H306-H398 AromaticContact CG-NE2 3.15Å; H306-H398 AromaticContact NE2-CD2 3.74Å; H306-H398 AromaticContact NE2-NE2 3.7Å; F371-H398 HydrophobicContact CE1-CB 4.29Å; G394-H398 PolarHBondContact O-CD2 2.95Å; G394-H398 PolarHBondContact O-N 3Å; S395-H398 PolarHBondContact O-N 3.1Å; I396-H398 PolarHBondContact O-N 2.97Å; H398-E401 IonicContact CE1-OE2 2.66Å; H398-E401 IonicContact ND1-OE2 3Å; H398-E401 PolarHBondContact ND1-OE2 3.36Å; H398-E401 PolarHBondContact O-N 2.94Å; H398-A402 VanDerWaalsContact O-CB 3.28Å; H398-A402 WeakPolarHBondContact O-CB 3.44Å; H398-A402 PolarHBondContact O-N 3.47Å
399	F	82.8	Confident	78.7	Confident	111 Å²	111	54.7 Å²	54.7	49%	0.487	28%	0.281	S	S	.	.	H	α-helix	trans	-62.3	-43.9	171.4	174.5	-95.9	0	0	0	111.6	Y362 S395 I396 L397 T403	Y362-F399 WeakPolarHBondContact OH-CD2 3.38Å; S395-F399 PolarHBondContact O-N 3.48Å; I396-F399 WeakPolarHBondContact O-CB 3.22Å; I396-F399 PolarHBondContact O-N 3.04Å; L397-F399 PolarHBondContact O-N 3.37Å; F399-T403 WeakPolarHBondContact O-CB 3.43Å; F399-T403 PolarHBondContact O-N 3.48Å; F399-T403 PolarHBondContact O-OG1 2.98Å
400	F	84.9	Confident	80.6	Confident	125 Å²	125	49.5 Å²	49.5	55%	0.548	27%	0.269	S	S	.	.	H	α-helix	trans	-64.6	-41.6	174.7	-78.8	-64.7	0	0	0	112.1	I396 L397 T403 L404	I396-F400 HydrophobicContact CG2-CD2 3.72Å; I396-F400 HydrophobicContact CG2-CE2 3.48Å; I396-F400 VanDerWaalsContact CG2-CE2 3.48Å; I396-F400 WeakPolarHBondContact O-CD2 3.38Å; I396-F400 PolarHBondContact O-N 3.25Å; L397-F400 PolarHBondContact O-N 3.45Å; F400-T403 PolarHBondContact O-N 3.27Å; F400-L404 WeakPolarHBondContact O-CB 3.47Å; F400-L404 PolarHBondContact O-N 3.42Å
401	E	84.3	Confident	82.3	Confident	4 Å²	4	49.4 Å²	49.4	2%	0.019	27%	0.265	C	S	.	.	H	α-helix	trans	-61.1	-47.9	176.8	-167.7	-178.1	-174.3	0	0	111.6	F292 I295 H358 L397 H398 T403 L404 A405	F292-E401 HydrophobicContact CD1-CG 4.06Å; F292-E401 HydrophobicContact CE1-CG 3.71Å; I295-E401 HydrophobicContact CD1-CB 4.41Å; I295-E401 HydrophobicContact CG2-CB 4.41Å; I295-E401 HydrophobicContact CG2-CG 4.28Å; H358-E401 VanDerWaalsContact CE1-CD 3.49Å; H358-E401 IonicContact CE1-OE1 3.56Å; L397-E401 WeakPolarHBondContact O-CB 3.29Å; L397-E401 PolarHBondContact O-N 3.46Å; H398-E401 IonicContact CE1-OE2 2.66Å; H398-E401 IonicContact ND1-OE2 3Å; H398-E401 PolarHBondContact ND1-OE2 3.36Å; H398-E401 PolarHBondContact O-N 2.94Å; E401-T403 VanDerWaalsContact C-N 3.34Å; E401-T403 PolarHBondContact O-N 3Å; E401-L404 CarbonylContact O-C 3.6Å; E401-L404 WeakPolarHBondContact O-CB 3.04Å; E401-L404 PolarHBondContact O-N 3.45Å; E401-A405 WeakPolarHBondContact O-CB 3.03Å; E401-A405 PolarHBondContact O-N 2.96Å
402	A	85.3	Confident	83.8	Confident	2 Å²	2	47.2 Å²	47.2	2%	0.017	26%	0.255	C	S	.	.	H	α-helix	trans	-63.8	-39.5	176.6	0	0	0	0	0	111.9	Y362 H398 A405 I406	Y362-A402 HydrophobicContact CD1-CB 3.66Å; Y362-A402 HydrophobicContact CD2-CB 3.52Å; Y362-A402 HydrophobicContact CE1-CB 3.93Å; Y362-A402 HydrophobicContact CE2-CB 3.79Å; Y362-A402 HydrophobicContact CG-CB 3.46Å; Y362-A402 VanDerWaalsContact CG-CB 3.46Å; H398-A402 VanDerWaalsContact O-CB 3.28Å; H398-A402 WeakPolarHBondContact O-CB 3.44Å; H398-A402 PolarHBondContact O-N 3.47Å; A402-A405 WeakPolarHBondContact O-CB 3.37Å; A402-A405 PolarHBondContact O-N 3.43Å; A402-I406 VanDerWaalsContact O-CG1 3.31Å; A402-I406 WeakPolarHBondContact O-CG1 3.45Å; A402-I406 PolarHBondContact O-N 2.93Å
403	T	89.5	Confident	85	Confident	66 Å²	66	46.1 Å²	46.1	41%	0.405	25%	0.252	S	S	.	.	H	α-helix	trans	-63.4	-43.1	175.1	-59	0	0	0	0	111.1	F399 F400 E401 A405 I406 A407	F399-T403 WeakPolarHBondContact O-CB 3.43Å; F399-T403 PolarHBondContact O-N 3.48Å; F399-T403 PolarHBondContact O-OG1 2.98Å; F400-T403 PolarHBondContact O-N 3.27Å; E401-T403 VanDerWaalsContact C-N 3.34Å; E401-T403 PolarHBondContact O-N 3Å; T403-A405 VanDerWaalsContact C-N 3.32Å; T403-I406 PolarHBondContact O-N 3.23Å; T403-A407 PolarHBondContact O-N 2.95Å; T403-A407 VanDerWaalsContact O-N 3.07Å
404	L	91.2	Very high	86.2	Confident	28 Å²	28	48.7 Å²	48.7	15%	0.147	25%	0.25	C	S	.	.	H	α-helix	trans	-63.6	-39.6	174.1	-175.3	64	0	0	0	111	L291 F292 I295 F400 E401 A407 V408	L291-L404 HydrophobicContact CB-CD2 3.73Å; L291-L404 HydrophobicContact CD1-CD1 4.3Å; L291-L404 HydrophobicContact CD1-CD2 4.45Å; F292-L404 HydrophobicContact CD1-CD2 4.08Å; F292-L404 HydrophobicContact CD2-CD2 3.66Å; F292-L404 HydrophobicContact CD2-CG 4.17Å; F292-L404 HydrophobicContact CE1-CB 4.39Å; F292-L404 HydrophobicContact CE1-CD2 3.97Å; F292-L404 HydrophobicContact CE1-CG 4.27Å; F292-L404 HydrophobicContact CE2-CB 4.36Å; F292-L404 HydrophobicContact CE2-CD2 3.53Å; F292-L404 HydrophobicContact CE2-CG 3.53Å; F292-L404 HydrophobicContact CG-CD2 3.92Å; F292-L404 HydrophobicContact CZ-CB 3.91Å; F292-L404 HydrophobicContact CZ-CD2 3.69Å; F292-L404 HydrophobicContact CZ-CG 3.58Å; I295-L404 HydrophobicContact CD1-CD2 4.29Å; F400-L404 WeakPolarHBondContact O-CB 3.47Å; F400-L404 PolarHBondContact O-N 3.42Å; E401-L404 CarbonylContact O-C 3.6Å; E401-L404 WeakPolarHBondContact O-CB 3.04Å; E401-L404 PolarHBondContact O-N 3.45Å; L404-A407 WeakPolarHBondContact O-CB 3.4Å; L404-A407 PolarHBondContact O-N 2.81Å; L404-V408 WeakPolarHBondContact O-CG2 2.99Å; L404-V408 PolarHBondContact O-N 3.39Å
405	A	89.2	Confident	87.4	Confident	0 Å²	0	48.6 Å²	48.6	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-65.7	-38.4	177.6	0	0	0	0	0	112.2	F292 T355 H358 V359 E401 A402 T403 V408 L409	F292-A405 HydrophobicContact CZ-CB 4.03Å; T355-A405 HydrophobicContact CG2-CB 4.47Å; H358-A405 HydrophobicContact CB-CB 4.39Å; H358-A405 WeakPolarHBondContact CD2-CB 2.71Å; V359-A405 HydrophobicContact CG2-CB 4.05Å; E401-A405 WeakPolarHBondContact O-CB 3.03Å; E401-A405 PolarHBondContact O-N 2.96Å; A402-A405 WeakPolarHBondContact O-CB 3.37Å; A402-A405 PolarHBondContact O-N 3.43Å; T403-A405 VanDerWaalsContact C-N 3.32Å; A405-V408 PolarHBondContact O-N 3.25Å; A405-L409 VanDerWaalsContact O-CB 3.3Å; A405-L409 WeakPolarHBondContact O-CB 3.31Å; A405-L409 PolarHBondContact O-N 3.15Å
406	I	92.3	Very high	88.4	Confident	80 Å²	80	47.5 Å²	47.5	41%	0.41	24%	0.242	S	C	.	.	H	α-helix	trans	-62.3	-44.4	172.1	-67.5	165.5	0	0	0	110.4	V359 A402 T403 V408 L409 L410	V359-I406 HydrophobicContact CG1-CG1 4.23Å; V359-I406 HydrophobicContact CG2-CG1 3.74Å; A402-I406 VanDerWaalsContact O-CG1 3.31Å; A402-I406 WeakPolarHBondContact O-CG1 3.45Å; A402-I406 PolarHBondContact O-N 2.93Å; T403-I406 PolarHBondContact O-N 3.23Å; I406-V408 VanDerWaalsContact C-N 3.35Å; I406-V408 PolarHBondContact O-N 2.97Å; I406-L409 WeakPolarHBondContact O-CB 3.43Å; I406-L409 PolarHBondContact O-N 2.87Å; I406-L410 HydrophobicContact CG2-CD1 4.5Å; I406-L410 WeakPolarHBondContact O-CG 3.28Å; I406-L410 PolarHBondContact O-N 3.44Å; I406-L410 VanDerWaalsContact O-N 3.1Å
407	A	93.9	Very high	89.1	Confident	46 Å²	46	49.2 Å²	49.2	38%	0.38	25%	0.246	S	C	.	.	H	α-helix	trans	-61.3	-44.3	176.5	0	0	0	0	0	111.4	T403 L404 L410 M411	T403-A407 PolarHBondContact O-N 2.95Å; T403-A407 VanDerWaalsContact O-N 3.07Å; L404-A407 WeakPolarHBondContact O-CB 3.4Å; L404-A407 PolarHBondContact O-N 2.81Å; A407-L410 PolarHBondContact O-N 2.82Å; A407-M411 WeakPolarHBondContact O-CB 3.45Å; A407-M411 WeakPolarHBondContact O-CG 3.11Å; A407-M411 PolarHBondContact O-N 2.94Å
408	V	93.8	Very high	89.8	Confident	0 Å²	0	48.7 Å²	48.7	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-67.7	-35.1	177.2	173.9	0	0	0	0	112.2	F292 L316 L320 T355 L404 A405 I406 L410 M411 S412	F292-V408 HydrophobicContact CE2-CG2 3.91Å; L316-V408 HydrophobicContact CD1-CG1 4.22Å; L320-V408 HydrophobicContact CD1-CG1 3.93Å; L320-V408 HydrophobicContact CD1-CG2 4.03Å; L320-V408 HydrophobicContact CD2-CG1 3.5Å; L320-V408 VanDerWaalsContact CD2-CG1 3.5Å; L320-V408 HydrophobicContact CG-CG1 4.28Å; T355-V408 HydrophobicContact CG2-CB 3.8Å; T355-V408 HydrophobicContact CG2-CG1 3.51Å; L404-V408 WeakPolarHBondContact O-CG2 2.99Å; L404-V408 PolarHBondContact O-N 3.39Å; A405-V408 PolarHBondContact O-N 3.25Å; I406-V408 VanDerWaalsContact C-N 3.35Å; I406-V408 PolarHBondContact O-N 2.97Å; V408-L410 PolarHBondContact O-N 2.87Å; V408-M411 PolarHBondContact O-N 3.11Å; V408-S412 WeakPolarHBondContact O-CB 3.39Å; V408-S412 PolarHBondContact O-N 2.9Å; V408-S412 PolarHBondContact O-OG 3.49Å
409	L	92.6	Very high	90.5	Very high	32 Å²	32	48.2 Å²	48.2	17%	0.168	24%	0.241	C	C	.	.	H	α-helix	trans	-57.5	-50.3	173.6	-175.7	76.7	0	0	0	110.2	F352 T355 M356 A405 I406 S412 I413	F352-L409 HydrophobicContact CD2-CD1 3.38Å; F352-L409 HydrophobicContact CD2-CG 4.2Å; F352-L409 HydrophobicContact CE2-CD1 3.48Å; F352-L409 VanDerWaalsContact CE2-CD1 3.48Å; F352-L409 HydrophobicContact CE2-CG 4.2Å; F352-L409 HydrophobicContact CG-CD1 4.41Å; T355-L409 WeakPolarHBondContact OG1-CA 3.47Å; T355-L409 WeakPolarHBondContact OG1-CD1 3.27Å; M356-L409 HydrophobicContact CB-CD1 3.98Å; A405-L409 VanDerWaalsContact O-CB 3.3Å; A405-L409 WeakPolarHBondContact O-CB 3.31Å; A405-L409 PolarHBondContact O-N 3.15Å; I406-L409 WeakPolarHBondContact O-CB 3.43Å; I406-L409 PolarHBondContact O-N 2.87Å; L409-S412 PolarHBondContact O-N 3.02Å; L409-I413 HydrophobicContact CG-CD1 4.46Å; L409-I413 WeakPolarHBondContact O-CG1 3.07Å; L409-I413 PolarHBondContact O-N 2.85Å
410	L	94.2	Very high	90.6	Very high	109 Å²	109	43.5 Å²	43.5	57%	0.571	22%	0.224	S	C	*	.	H	α-helix	trans	-63.6	-43.5	177.8	-65.9	175	0	0	0	112.1	I406 A407 V408 S412 I413 Y414	I406-L410 HydrophobicContact CG2-CD1 4.5Å; I406-L410 WeakPolarHBondContact O-CG 3.28Å; I406-L410 PolarHBondContact O-N 3.44Å; I406-L410 VanDerWaalsContact O-N 3.1Å; A407-L410 PolarHBondContact O-N 2.82Å; V408-L410 PolarHBondContact O-N 2.87Å; L410-S412 VanDerWaalsContact C-N 3.31Å; L410-S412 PolarHBondContact O-N 3.39Å; L410-I413 PolarHBondContact O-N 3.33Å; L410-Y414 WeakPolarHBondContact O-CB 3.18Å; L410-Y414 PolarHBondContact O-N 2.62Å
411	M	93.9	Very high	90.7	Very high	53 Å²	53	44.6 Å²	44.6	26%	0.261	22%	0.224	S	C	.	.	H	α-helix	trans	-63.6	-36.9	176	-71.5	-69.1	-80.7	0	0	112	F281 A407 V408 G415	F281-M411 HydrophobicContact CD2-CE 3.25Å; F281-M411 HydrophobicContact CD2-SD 4.11Å; F281-M411 HydrophobicContact CE2-CB 4.11Å; F281-M411 HydrophobicContact CE2-CE 3.52Å; F281-M411 VanDerWaalsContact CE2-O 3.28Å; F281-M411 WeakPolarHBondContact CE2-O 3.05Å; F281-M411 HydrophobicContact CE2-SD 4.06Å; F281-M411 HydrophobicContact CG-CE 4.22Å; F281-M411 WeakPolarHBondContact CZ-O 3.24Å; A407-M411 WeakPolarHBondContact O-CB 3.45Å; A407-M411 WeakPolarHBondContact O-CG 3.11Å; A407-M411 PolarHBondContact O-N 2.94Å; V408-M411 PolarHBondContact O-N 3.11Å; M411-G415 WeakPolarHBondContact O-CA 3.45Å; M411-G415 PolarHBondContact O-N 2.73Å
412	S	93.3	Very high	90.8	Very high	0 Å²	0	44.5 Å²	44.5	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-68.9	-40.2	178.3	-61.2	0	0	0	0	111.6	L348 S351 V408 L409 L410 S416	L348-S412 WeakPolarHBondContact O-CB 3.19Å; S351-S412 WeakPolarHBondContact CB-OG 3.45Å; V408-S412 WeakPolarHBondContact O-CB 3.39Å; V408-S412 PolarHBondContact O-N 2.9Å; V408-S412 PolarHBondContact O-OG 3.49Å; L409-S412 PolarHBondContact O-N 3.02Å; L410-S412 VanDerWaalsContact C-N 3.31Å; L410-S412 PolarHBondContact O-N 3.39Å; S412-S416 VanDerWaalsContact O-CB 3.22Å; S412-S416 WeakPolarHBondContact O-CB 3.3Å; S412-S416 PolarHBondContact O-N 3.04Å; S412-S416 PolarHBondContact O-OG 3.45Å
413	I	92.3	Very high	90.6	Very high	84 Å²	84	44.4 Å²	44.4	43%	0.431	22%	0.223	S	C	.	.	H	α-helix	trans	-62.7	-53.5	172.7	-65.6	163.6	0	0	0	110.2	F352 L409 L410 G415 S416 F417	F352-I413 HydrophobicContact CD2-CD1 4.16Å; F352-I413 HydrophobicContact CD2-CG1 3.62Å; F352-I413 HydrophobicContact CE2-CD1 3.78Å; F352-I413 HydrophobicContact CE2-CG1 3.63Å; L409-I413 HydrophobicContact CG-CD1 4.46Å; L409-I413 WeakPolarHBondContact O-CG1 3.07Å; L409-I413 PolarHBondContact O-N 2.85Å; L410-I413 PolarHBondContact O-N 3.33Å; I413-G415 PolarHBondContact O-N 2.8Å; I413-S416 PolarHBondContact O-N 3.19Å; I413-F417 PolarHBondContact O-N 3.44Å; I413-F417 VanDerWaalsContact O-N 3.09Å
414	Y	92.8	Very high	90	Very high	113 Å²	113	42.8 Å²	42.8	44%	0.443	22%	0.215	S	C	.	.	H	α-helix	trans	-58.2	-48	-179.7	173	-100.9	0	0	0	111.5	F281 L410 F417 L418	F281-Y414 HydrophobicContact CD2-CD1 4.06Å; F281-Y414 HydrophobicContact CD2-CE1 4.3Å; F281-Y414 HydrophobicContact CE2-CD1 4.01Å; L410-Y414 WeakPolarHBondContact O-CB 3.18Å; L410-Y414 PolarHBondContact O-N 2.62Å; Y414-F417 PolarHBondContact O-N 3.38Å; Y414-L418 HydrophobicContact CE1-CD2 3.96Å; Y414-L418 WeakPolarHBondContact O-CB 3.29Å; Y414-L418 PolarHBondContact O-N 2.8Å
415	G	92.1	Very high	89.2	Confident	0 Å²	0	48.2 Å²	48.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-65.1	-43.5	179.8	0	0	0	0	0	112.4	F281 L348 M411 I413 F417 L418 F419	F281-G415 VanDerWaalsContact CZ-CA 3.49Å; L348-G415 VanDerWaalsContact CD1-C 3.46Å; M411-G415 WeakPolarHBondContact O-CA 3.45Å; M411-G415 PolarHBondContact O-N 2.73Å; I413-G415 PolarHBondContact O-N 2.8Å; G415-F417 PolarHBondContact O-N 3.3Å; G415-L418 PolarHBondContact O-N 2.86Å; G415-F419 WeakPolarHBondContact O-CB 3.28Å; G415-F419 VanDerWaalsContact O-CD2 3.32Å; G415-F419 WeakPolarHBondContact O-CD2 3.27Å; G415-F419 PolarHBondContact O-N 3.22Å
416	S	90.6	Very high	88.2	Confident	24 Å²	24	49 Å²	49	17%	0.168	24%	0.24	C	C	.	.	H	α-helix	trans	-58.9	-39.9	176.8	-62	0	0	0	0	111.3	L348 S412 I413 G420	L348-S416 WeakPolarHBondContact CB-OG 3.45Å; S412-S416 VanDerWaalsContact O-CB 3.22Å; S412-S416 WeakPolarHBondContact O-CB 3.3Å; S412-S416 PolarHBondContact O-N 3.04Å; S412-S416 PolarHBondContact O-OG 3.45Å; I413-S416 PolarHBondContact O-N 3.19Å; S416-G420 WeakPolarHBondContact O-CA 3.41Å; S416-G420 PolarHBondContact O-N 2.92Å
417	F	90.2	Very high	87	Confident	113 Å²	113	52.4 Å²	52.4	50%	0.496	25%	0.248	S	C	.	.	H	α-helix	trans	-68.8	-45.5	174.5	-175.5	-99.5	0	0	0	112.6	I413 Y414 G415 G420 R421	I413-F417 PolarHBondContact O-N 3.44Å; I413-F417 VanDerWaalsContact O-N 3.09Å; Y414-F417 PolarHBondContact O-N 3.38Å; G415-F417 PolarHBondContact O-N 3.3Å; F417-G420 PolarHBondContact O-N 3.4Å; F417-R421 HydrophobicContact CE1-CG 4.3Å; F417-R421 HydrophobicContact CZ-CG 4.44Å; F417-R421 VanDerWaalsContact CZ-CZ 3.45Å; F417-R421 WeakPolarHBondContact O-CB 3.47Å; F417-R421 WeakPolarHBondContact O-CG 3.5Å; F417-R421 PolarHBondContact O-N 3.4Å
418	L	90.9	Very high	85.6	Confident	23 Å²	23	51.7 Å²	51.7	12%	0.12	24%	0.238	C	C	.	.	H	α-helix	trans	-59.8	-55.4	179	178.3	63.7	0	0	0	111.2	L274 I278 Y414 G415 R421 L422	L274-L418 HydrophobicContact CD1-CD1 4.16Å; I278-L418 HydrophobicContact CG1-CD2 4.13Å; Y414-L418 HydrophobicContact CE1-CD2 3.96Å; Y414-L418 WeakPolarHBondContact O-CB 3.29Å; Y414-L418 PolarHBondContact O-N 2.8Å; G415-L418 PolarHBondContact O-N 2.86Å; L418-R421 WeakPolarHBondContact O-CB 3.46Å; L418-R421 PolarHBondContact O-N 2.9Å; L418-R421 VanDerWaalsContact O-N 3.17Å; L418-L422 WeakPolarHBondContact O-CG 3.3Å; L418-L422 PolarHBondContact O-N 3.29Å
419	F	89.4	Confident	83.8	Confident	0 Å²	0	57.7 Å²	57.7	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-69	-33.8	-179.5	-76.3	-89.8	0	0	0	112.2	I278 F281 A327 I341 V344 T345 L348 G415 R421 L422 C423	I278-F419 HydrophobicContact CG2-CZ 3.93Å; F281-F419 AromaticContact CD1-CE2 3.87Å; F281-F419 HydrophobicContact CD1-CE2 3.87Å; F281-F419 HydrophobicContact CE1-CD2 4.4Å; F281-F419 AromaticContact CE1-CE2 3.74Å; F281-F419 HydrophobicContact CE1-CE2 3.74Å; A327-F419 HydrophobicContact CB-CE1 4.29Å; A327-F419 HydrophobicContact CB-CE2 4.32Å; A327-F419 HydrophobicContact CB-CZ 3.58Å; I341-F419 HydrophobicContact CB-CD1 4.23Å; I341-F419 HydrophobicContact CG1-CD1 4.05Å; I341-F419 HydrophobicContact CG1-CE1 4.32Å; I341-F419 HydrophobicContact CG2-CB 4.34Å; I341-F419 HydrophobicContact CG2-CD1 4.02Å; I341-F419 WeakPolarHBondContact CG2-O 3.31Å; V344-F419 HydrophobicContact CB-CD1 3.95Å; V344-F419 HydrophobicContact CB-CE1 4.12Å; V344-F419 HydrophobicContact CB-CG 4.25Å; V344-F419 HydrophobicContact CG1-CB 4.5Å; V344-F419 HydrophobicContact CG1-CD1 3.74Å; V344-F419 HydrophobicContact CG1-CD2 3.62Å; V344-F419 HydrophobicContact CG1-CE1 3.78Å; V344-F419 HydrophobicContact CG1-CE2 3.66Å; V344-F419 HydrophobicContact CG1-CG 3.68Å; V344-F419 HydrophobicContact CG1-CZ 3.75Å; V344-F419 HydrophobicContact CG2-CE1 4.3Å; T345-F419 WeakPolarHBondContact OG1-CB 3.46Å; L348-F419 HydrophobicContact CD1-CD2 3.99Å; G415-F419 WeakPolarHBondContact O-CB 3.28Å; G415-F419 VanDerWaalsContact O-CD2 3.32Å; G415-F419 WeakPolarHBondContact O-CD2 3.27Å; G415-F419 PolarHBondContact O-N 3.22Å; F419-R421 VanDerWaalsContact C-N 3.32Å; F419-R421 PolarHBondContact O-N 3.27Å; F419-L422 HydrophobicContact CD1-CD1 3.92Å; F419-L422 HydrophobicContact CE1-CD1 4.11Å; F419-L422 HydrophobicContact CG-CD1 4.36Å; F419-L422 WeakPolarHBondContact O-CB 3.22Å; F419-L422 PolarHBondContact O-N 3.44Å; F419-L422 VanDerWaalsContact O-N 3.15Å; F419-C423 PolarHBondContact O-N 2.95Å; F419-C423 PolarHBondContact O-SG 3.14Å
420	G	86	Confident	81.9	Confident	11 Å²	11	57.6 Å²	57.6	11%	0.113	27%	0.273	C	S	.	.	H	α-helix	trans	-62	-36.9	170	0	0	0	0	0	113	S416 F417 C423 S424	S416-G420 WeakPolarHBondContact O-CA 3.41Å; S416-G420 PolarHBondContact O-N 2.92Å; F417-G420 PolarHBondContact O-N 3.4Å; G420-C423 WeakPolarHBondContact O-CB 3.44Å; G420-S424 PolarHBondContact O-OG 3.37Å
421	R	87	Confident	79.6	Confident	148 Å²	148	57.3 Å²	57.3	56%	0.558	28%	0.281	S	S	*	.	H	α-helix	trans	-70.8	-37.7	170.2	-77.4	-153.1	176.1	-175.9	-0.2	112.4	F417 L418 F419 C423 S424 F425	F417-R421 HydrophobicContact CE1-CG 4.3Å; F417-R421 HydrophobicContact CZ-CG 4.44Å; F417-R421 VanDerWaalsContact CZ-CZ 3.45Å; F417-R421 WeakPolarHBondContact O-CB 3.47Å; F417-R421 WeakPolarHBondContact O-CG 3.5Å; F417-R421 PolarHBondContact O-N 3.4Å; L418-R421 WeakPolarHBondContact O-CB 3.46Å; L418-R421 PolarHBondContact O-N 2.9Å; L418-R421 VanDerWaalsContact O-N 3.17Å; F419-R421 VanDerWaalsContact C-N 3.32Å; F419-R421 PolarHBondContact O-N 3.27Å; R421-C423 VanDerWaalsContact C-N 3.26Å; R421-C423 PolarHBondContact O-N 3.23Å; R421-S424 WeakPolarHBondContact O-CA 3.46Å; R421-S424 WeakPolarHBondContact O-CB 3.49Å; R421-S424 PolarHBondContact O-N 2.9Å; R421-F425 PolarHBondContact O-N 2.98Å
422	L	85.4	Confident	77.3	Confident	3 Å²	3	58 Å²	58	2%	0.016	30%	0.302	C	S	.	.	H	α-helix	trans	-58.5	-38.8	174.4	-68.5	175.7	0	0	0	111.8	L268 L274 I278 I341 L418 F419 S424 F425 Y426	L268-L422 HydrophobicContact CD2-CD2 4.43Å; L274-L422 HydrophobicContact CD2-CD2 4.32Å; I278-L422 HydrophobicContact CD1-CD1 3.93Å; I341-L422 HydrophobicContact CD1-CB 4.16Å; I341-L422 HydrophobicContact CD1-CD1 4.43Å; I341-L422 HydrophobicContact CG2-CB 3.93Å; L418-L422 WeakPolarHBondContact O-CG 3.3Å; L418-L422 PolarHBondContact O-N 3.29Å; F419-L422 HydrophobicContact CD1-CD1 3.92Å; F419-L422 HydrophobicContact CE1-CD1 4.11Å; F419-L422 HydrophobicContact CG-CD1 4.36Å; F419-L422 WeakPolarHBondContact O-CB 3.22Å; F419-L422 PolarHBondContact O-N 3.44Å; F419-L422 VanDerWaalsContact O-N 3.15Å; L422-S424 PolarHBondContact O-N 3.09Å; L422-S424 VanDerWaalsContact O-N 3.07Å; L422-F425 HydrophobicContact CD2-CD2 4.01Å; L422-F425 HydrophobicContact CD2-CE2 4.29Å; L422-F425 PolarHBondContact O-N 3.36Å; L422-F425 VanDerWaalsContact O-N 3.14Å; L422-Y426 WeakPolarHBondContact O-CD2 3.23Å
423	C	81.7	Confident	74.9	Confident	0 Å²	0	61 Å²	61	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-56.2	-24.3	171	-69.7	0	0	0	0	113.5	I341 F419 G420 R421 L510 M519 K520	I341-C423 VanDerWaalsContact CG2-SG 3.54Å; F419-C423 PolarHBondContact O-N 2.95Å; F419-C423 PolarHBondContact O-SG 3.14Å; G420-C423 WeakPolarHBondContact O-CB 3.44Å; R421-C423 VanDerWaalsContact C-N 3.26Å; R421-C423 PolarHBondContact O-N 3.23Å; C423-L510 HydrophobicContact CB-CD2 4.38Å; C423-M519 HydrophobicContact CB-CB 4.26Å; C423-K520 HydrophobicContact CB-CG 4Å
424	S	77	Confident	72.8	Confident	32 Å²	32	66.2 Å²	66.2	22%	0.224	34%	0.337	C	S	.	.	H	α-helix	trans	-85	-20.8	-179.3	-55	0	0	0	0	114.5	G420 R421 L422 Y426 R427 K520	G420-S424 PolarHBondContact O-OG 3.37Å; R421-S424 WeakPolarHBondContact O-CA 3.46Å; R421-S424 WeakPolarHBondContact O-CB 3.49Å; R421-S424 PolarHBondContact O-N 2.9Å; L422-S424 PolarHBondContact O-N 3.09Å; L422-S424 VanDerWaalsContact O-N 3.07Å; S424-Y426 VanDerWaalsContact C-N 3.33Å; S424-R427 WeakPolarHBondContact O-CG 3.1Å; S424-R427 PolarHBondContact O-NE 2.83Å; S424-K520 WeakPolarHBondContact OG-CE 3.34Å; S424-K520 PolarHBondContact OG-NZ 3.5Å
425	F	75	Confident	70.8	Confident	142 Å²	142	65.5 Å²	65.5	62%	0.623	34%	0.343	S	S	*	.	H	α-helix	trans	-77	-24.9	177.7	-68.5	-56.3	0	0	0	112.1	L268 R421 L422 R427	L268-F425 HydrophobicContact CD1-CB 4.43Å; R421-F425 PolarHBondContact O-N 2.98Å; L422-F425 HydrophobicContact CD2-CD2 4.01Å; L422-F425 HydrophobicContact CD2-CE2 4.29Å; L422-F425 PolarHBondContact O-N 3.36Å; L422-F425 VanDerWaalsContact O-N 3.14Å; F425-R427 VanDerWaalsContact C-N 3.3Å; F425-R427 PolarHBondContact O-N 3.37Å
426	Y	68.7	Low	69.2	Low	17 Å²	17	70.7 Å²	70.7	7%	0.067	38%	0.38	C	S	.	.			trans	-78.2	86.9	170	-70.3	-91	0	0	0	109.6	L266 L268 S337 I341 L422 S424 S517 M519	L266-Y426 HydrophobicContact CD2-CD1 3.44Å; L266-Y426 VanDerWaalsContact CD2-CD1 3.44Å; L266-Y426 HydrophobicContact CD2-CE1 3.71Å; L266-Y426 HydrophobicContact CG-CD1 4.21Å; L266-Y426 HydrophobicContact CG-CE1 4.31Å; L268-Y426 HydrophobicContact CB-CE2 4.48Å; L268-Y426 WeakPolarHBondContact CB-OH 3.5Å; L268-Y426 HydrophobicContact CD1-CD2 4.22Å; L268-Y426 HydrophobicContact CD1-CE2 3.56Å; L268-Y426 HydrophobicContact CD2-CE2 4.36Å; L268-Y426 HydrophobicContact CG-CE2 4.35Å; S337-Y426 WeakPolarHBondContact CB-OH 3.28Å; I341-Y426 HydrophobicContact CD1-CE2 3.83Å; L422-Y426 WeakPolarHBondContact O-CD2 3.23Å; S424-Y426 VanDerWaalsContact C-N 3.33Å; Y426-S517 WeakPolarHBondContact O-CA 3.37Å; Y426-S517 WeakPolarHBondContact O-CB 3.29Å; Y426-S517 PolarHBondContact O-OG 3.48Å; Y426-M519 WeakPolarHBondContact CB-SD 3.47Å; Y426-M519 HydrophobicContact CD1-SD 3.69Å; Y426-M519 HydrophobicContact CD2-CE 3.87Å; Y426-M519 HydrophobicContact CD2-SD 3.03Å; Y426-M519 WeakPolarHBondContact CD2-SD 3.39Å; Y426-M519 HydrophobicContact CE1-SD 4.05Å; Y426-M519 HydrophobicContact CE2-CE 3.92Å; Y426-M519 HydrophobicContact CE2-SD 3.44Å; Y426-M519 WeakPolarHBondContact CE2-SD 3.45Å; Y426-M519 HydrophobicContact CG-CE 4.47Å; Y426-M519 HydrophobicContact CG-CG 4.27Å; Y426-M519 HydrophobicContact CG-SD 3.1Å
427	R	67.1	Low	68.1	Low	150 Å²	150	72.6 Å²	72.6	57%	0.566	39%	0.387	S	S	*	.			trans	-107.1	140.6	168.8	-67	-177.4	179.6	-167	-1.5	108.2	S424 F425 L516	S424-R427 WeakPolarHBondContact O-CG 3.1Å; S424-R427 PolarHBondContact O-NE 2.83Å; F425-R427 VanDerWaalsContact C-N 3.3Å; F425-R427 PolarHBondContact O-N 3.37Å; R427-L516 CarbonylContact C-O 3.6Å; R427-L516 VanDerWaalsContact CA-O 3.3Å; R427-L516 WeakPolarHBondContact CA-O 3.38Å
428	I	63	Low	67.3	Low	32 Å²	32	69.7 Å²	69.7	16%	0.164	38%	0.381	C	S	.	.			trans	-80.3	122.9	167	-30.4	177.3	0	0	0	106.9	F261 A430 L516 P518 S579 Y583	F261-I428 HydrophobicContact CE1-CD1 4.14Å; I428-A430 PolarHBondContact O-N 2.93Å; I428-L516 PolarHBondContact N-O 3.03Å; I428-P518 HydrophobicContact CD1-CG 3.96Å; I428-P518 HydrophobicContact CG1-CG 3.99Å; I428-S579 WeakPolarHBondContact CD1-OG 3.48Å; I428-Y583 HydrophobicContact CB-CE2 4.07Å; I428-Y583 WeakPolarHBondContact CB-OH 3.4Å; I428-Y583 HydrophobicContact CD1-CE2 3.71Å; I428-Y583 HydrophobicContact CG2-CE1 3.72Å; I428-Y583 HydrophobicContact CG2-CE2 3.59Å; I428-Y583 WeakPolarHBondContact CG2-OH 3.42Å
429	D	57	Low	66.8	Low	125 Å²	125	72.9 Å²	72.9	67%	0.668	41%	0.41	S	S	*	.			trans	-61.3	112.5	-178.1	-85.2	-26.2	0	0	0	109.5	S431 Y583	D429-S431 PolarHBondContact O-N 3.41Å; D429-Y583 PolarHBondContact O-OH 3.25Å
430	A	51.7	Low	66.3	Low	30 Å²	30	78.3 Å²	78.3	25%	0.248	44%	0.436	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.3	9	179.6	0	0	0	0	0	112.6	I428 R434	I428-A430 PolarHBondContact O-N 2.93Å; A430-R434 PolarHBondContact O-NE 3.29Å
431	S	46.2	Very low	65.8	Low	104 Å²	104	81.2 Å²	81.2	73%	0.727	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.3	-17.4	-175.5	47.5	0	0	0	0	113.8	D429	D429-S431 PolarHBondContact O-N 3.41Å
432	G	46	Very low	65.5	Low	68 Å²	68	78.2 Å²	78.2	70%	0.701	44%	0.444	S	S	*	.	S	Bend	trans	-85.9	-29.1	-168.6	0	0	0	0	0	117.5
433	S	41.8	Very low	65.4	Low	62 Å²	62	86.8 Å²	86.8	43%	0.434	48%	0.476	S	S	.	.			trans	-178	82.1	173.2	61.1	0	0	0	0	109	V435	S433-V435 VanDerWaalsContact C-N 3.34Å; S433-V435 PolarHBondContact O-N 2.99Å
434	R	48.4	Very low	65.4	Low	194 Å²	194	92.3 Å²	92.3	73%	0.732	50%	0.497	S	S	*	.			trans	-70.7	101.7	164	-73.4	-171.3	-158.4	-172.2	3.9	106.9	A430 S436	A430-R434 PolarHBondContact O-NE 3.29Å; R434-S436 PolarHBondContact O-N 3.41Å; R434-S436 VanDerWaalsContact O-N 3.17Å
435	V	52.4	Low	65.7	Low	97 Å²	97	91.3 Å²	91.3	59%	0.588	49%	0.489	S	S	*	.			trans	-51	123.9	147.6	-179.5	0	0	0	0	104.9	S433 M437 P584	S433-V435 VanDerWaalsContact C-N 3.34Å; S433-V435 PolarHBondContact O-N 2.99Å; V435-M437 PolarHBondContact O-N 3.15Å; V435-P584 HydrophobicContact CG2-CG 4.34Å
436	S	57.6	Low	66.3	Low	109 Å²	109	86 Å²	86	76%	0.762	48%	0.475	S	S	*	.			trans	-56.3	103.7	-178.1	53.8	0	0	0	0	108.5	R434 S438	R434-S436 PolarHBondContact O-N 3.41Å; R434-S436 VanDerWaalsContact O-N 3.17Å; S436-S438 PolarHBondContact O-N 3.29Å
437	M	67.3	Low	67.2	Low	65 Å²	65	88.1 Å²	88.1	32%	0.32	49%	0.487	S	S	.	.			trans	-59	129.2	177.5	-60.5	-171.3	78.1	0	0	107.9	V435 E441 V442 I445	V435-M437 PolarHBondContact O-N 3.15Å; M437-E441 HydrophobicContact CE-CB 4.13Å; M437-V442 HydrophobicContact CB-CG2 3.98Å; M437-I445 HydrophobicContact CE-CD1 3.28Å; M437-I445 HydrophobicContact SD-CD1 4.27Å
438	S	74.5	Confident	68.1	Low	52 Å²	52	81.9 Å²	81.9	36%	0.364	47%	0.466	S	S	.	.			trans	-59.6	149.2	176.8	65.3	0	0	0	0	110	S436 Q440 E441 V442	S436-S438 PolarHBondContact O-N 3.29Å; S438-Q440 PolarHBondContact O-N 3.43Å; S438-E441 WeakPolarHBondContact CB-OE2 3.45Å; S438-E441 PolarHBondContact N-OE2 3.44Å; S438-E441 PolarHBondContact O-N 3.29Å; S438-E441 VanDerWaalsContact OG-CD 3.24Å; S438-E441 WeakPolarHBondContact OG-CG 3.49Å; S438-E441 PolarHBondContact OG-N 2.91Å; S438-E441 PolarHBondContact OG-OE2 2.8Å; S438-V442 PolarHBondContact O-N 2.9Å; S438-V442 VanDerWaalsContact O-N 3.12Å
439	A	78.9	Confident	69.3	Low	89 Å²	89	81.3 Å²	81.3	74%	0.736	46%	0.463	S	S	*	.	H	α-helix	trans	-55	-28.9	175.8	0	0	0	0	0	112.2	R443	A439-R443 WeakPolarHBondContact O-CB 3.21Å; A439-R443 PolarHBondContact O-N 2.79Å; A439-R443 VanDerWaalsContact O-N 3.08Å
440	Q	80	Confident	71	Confident	115 Å²	115	83.5 Å²	83.5	54%	0.537	46%	0.462	S	S	.	.	H	α-helix	trans	-67.8	-42	175.2	-170.3	176.6	2.6	0	0	112.5	S438 R443 R444	S438-Q440 PolarHBondContact O-N 3.43Å; Q440-R443 PolarHBondContact O-N 2.93Å; Q440-R444 WeakPolarHBondContact O-CG 3.18Å; Q440-R444 PolarHBondContact O-N 2.92Å
441	E	75.2	Confident	72.9	Confident	72 Å²	72	85.2 Å²	85.2	34%	0.336	47%	0.469	S	S	.	.	H	α-helix	trans	-67.6	-43.6	177.5	-71.3	164.4	135.7	0	0	111.7	M437 S438 R443 R444 I445 F578	M437-E441 HydrophobicContact CE-CB 4.13Å; S438-E441 WeakPolarHBondContact CB-OE2 3.45Å; S438-E441 PolarHBondContact N-OE2 3.44Å; S438-E441 PolarHBondContact O-N 3.29Å; S438-E441 VanDerWaalsContact OG-CD 3.24Å; S438-E441 WeakPolarHBondContact OG-CG 3.49Å; S438-E441 PolarHBondContact OG-N 2.91Å; S438-E441 PolarHBondContact OG-OE2 2.8Å; E441-R443 VanDerWaalsContact C-N 3.27Å; E441-R443 PolarHBondContact O-N 2.98Å; E441-R444 WeakPolarHBondContact O-CB 3.3Å; E441-R444 PolarHBondContact O-N 3.3Å; E441-R444 VanDerWaalsContact O-N 3.09Å; E441-I445 WeakPolarHBondContact O-CG1 3.46Å; E441-I445 PolarHBondContact O-N 3.35Å; E441-F578 HydrophobicContact CB-CE1 4.2Å; E441-F578 HydrophobicContact CG-CE1 3.95Å
442	V	80.2	Confident	74.9	Confident	84 Å²	84	80.2 Å²	80.2	51%	0.509	43%	0.434	S	S	.	.	H	α-helix	trans	-57.6	-43.7	174.3	177.6	0	0	0	0	110.4	M437 S438 I445 G446	M437-V442 HydrophobicContact CB-CG2 3.98Å; S438-V442 PolarHBondContact O-N 2.9Å; S438-V442 VanDerWaalsContact O-N 3.12Å; V442-I445 PolarHBondContact O-N 3.37Å; V442-G446 PolarHBondContact O-N 3.22Å
443	R	84.6	Confident	77.2	Confident	184 Å²	184	81.7 Å²	81.7	69%	0.694	42%	0.418	S	S	*	.	H	α-helix	trans	-64	-41.1	175.8	-168.6	177.1	-175.2	-175.9	1.7	112.2	A439 Q440 E441 G446 N447	A439-R443 WeakPolarHBondContact O-CB 3.21Å; A439-R443 PolarHBondContact O-N 2.79Å; A439-R443 VanDerWaalsContact O-N 3.08Å; Q440-R443 PolarHBondContact O-N 2.93Å; E441-R443 VanDerWaalsContact C-N 3.27Å; E441-R443 PolarHBondContact O-N 2.98Å; R443-G446 PolarHBondContact O-N 2.87Å; R443-N447 PolarHBondContact O-N 3.07Å; R443-N447 PolarHBondContact O-OD1 2.9Å
444	R	81.1	Confident	79.6	Confident	115 Å²	115	80.6 Å²	80.6	43%	0.434	42%	0.416	S	S	.	.	H	α-helix	trans	-64	-43.5	176.7	-76	178.3	-175.4	-166.4	6.7	112	Q440 E441 N447 C448 F578	Q440-R444 WeakPolarHBondContact O-CG 3.18Å; Q440-R444 PolarHBondContact O-N 2.92Å; E441-R444 WeakPolarHBondContact O-CB 3.3Å; E441-R444 PolarHBondContact O-N 3.3Å; E441-R444 VanDerWaalsContact O-N 3.09Å; R444-N447 WeakPolarHBondContact O-CB 3.4Å; R444-N447 PolarHBondContact O-N 3.37Å; R444-C448 PolarHBondContact O-N 2.86Å; R444-C448 PolarHBondContact O-SG 3.34Å; R444-F578 HydrophobicContact CB-CE2 4.15Å; R444-F578 HydrophobicContact CB-CZ 4.01Å
445	I	83.5	Confident	81.7	Confident	12 Å²	12	71.7 Å²	71.7	6%	0.062	38%	0.384	C	S	.	.	H	α-helix	trans	-60	-48	174.6	-71.6	172.2	0	0	0	110.1	M437 E441 V442 N447 C448 H449 H515 L575 F578	M437-I445 HydrophobicContact CE-CD1 3.28Å; M437-I445 HydrophobicContact SD-CD1 4.27Å; E441-I445 WeakPolarHBondContact O-CG1 3.46Å; E441-I445 PolarHBondContact O-N 3.35Å; V442-I445 PolarHBondContact O-N 3.37Å; I445-N447 VanDerWaalsContact C-N 3.3Å; I445-N447 PolarHBondContact O-N 2.86Å; I445-C448 PolarHBondContact O-N 3.37Å; I445-H449 PolarHBondContact O-CD2 3.35Å; I445-H449 PolarHBondContact O-N 3.27Å; I445-H515 HydrophobicContact CG2-CB 4.46Å; I445-L575 HydrophobicContact CB-CD2 4.34Å; I445-L575 HydrophobicContact CG1-CD2 4.41Å; I445-L575 HydrophobicContact CG2-CD2 3.91Å; I445-F578 HydrophobicContact CD1-CB 4.09Å; I445-F578 HydrophobicContact CD1-CD1 4.44Å; I445-F578 HydrophobicContact CD1-CD2 4.2Å; I445-F578 HydrophobicContact CD1-CG 4.01Å; I445-F578 HydrophobicContact CG1-CB 4.33Å; I445-F578 HydrophobicContact CG1-CD2 3.58Å; I445-F578 HydrophobicContact CG1-CE2 3.96Å; I445-F578 HydrophobicContact CG1-CG 3.92Å
446	G	86.2	Confident	83.6	Confident	31 Å²	31	67 Å²	67	32%	0.32	36%	0.356	S	S	.	.	H	α-helix	trans	-58.4	-39.7	175.8	0	0	0	0	0	113.1	V442 R443 R450	V442-G446 PolarHBondContact O-N 3.22Å; R443-G446 PolarHBondContact O-N 2.87Å; G446-R450 WeakPolarHBondContact O-CG 3.33Å; G446-R450 PolarHBondContact O-N 3.22Å; G446-R450 VanDerWaalsContact O-N 3.14Å
447	N	88.5	Confident	85.4	Confident	61 Å²	61	68.6 Å²	68.6	33%	0.326	35%	0.346	S	S	.	.	H	α-helix	trans	-64.2	-45.8	174.4	-67.3	-4.6	0	0	0	111.8	R443 R444 I445 H449 R450 V451	R443-N447 PolarHBondContact O-N 3.07Å; R443-N447 PolarHBondContact O-OD1 2.9Å; R444-N447 WeakPolarHBondContact O-CB 3.4Å; R444-N447 PolarHBondContact O-N 3.37Å; I445-N447 VanDerWaalsContact C-N 3.3Å; I445-N447 PolarHBondContact O-N 2.86Å; N447-H449 PolarHBondContact O-N 2.91Å; N447-R450 WeakPolarHBondContact O-CB 3.19Å; N447-R450 PolarHBondContact O-N 3.23Å; N447-R450 VanDerWaalsContact O-N 3.17Å; N447-R450 PolarHBondContact OD1-NH2 3.45Å; N447-V451 WeakPolarHBondContact O-CG2 3.5Å; N447-V451 PolarHBondContact O-N 3.1Å
448	C	86	Confident	86.7	Confident	18 Å²	18	67.3 Å²	67.3	12%	0.122	35%	0.345	C	S	.	.	H	α-helix	trans	-64.2	-41.9	-179.4	-63.8	0	0	0	0	111.8	R444 I445 R450 V451 V452 A571 V574 L575	R444-C448 PolarHBondContact O-N 2.86Å; R444-C448 PolarHBondContact O-SG 3.34Å; I445-C448 PolarHBondContact O-N 3.37Å; C448-R450 VanDerWaalsContact C-N 3.3Å; C448-R450 PolarHBondContact O-N 3.35Å; C448-V451 PolarHBondContact O-N 3.11Å; C448-V452 WeakPolarHBondContact O-CG2 3.29Å; C448-V452 PolarHBondContact O-N 2.88Å; C448-A571 HydrophobicContact CB-CB 4.49Å; C448-V574 VanDerWaalsContact SG-CG1 3.53Å; C448-L575 HydrophobicContact CB-CD1 4.11Å; C448-L575 HydrophobicContact CB-CD2 3.72Å; C448-L575 HydrophobicContact CB-CG 3.71Å
449	H	88.9	Confident	87.6	Confident	21 Å²	21	64.9 Å²	64.9	10%	0.097	33%	0.328	C	S	.	.	H	α-helix	trans	-59.4	-40.9	172.7	-78.5	-66.9	0	0	0	112.4	I445 N447 V452 R453 S511 V514 H515	I445-H449 PolarHBondContact O-CD2 3.35Å; I445-H449 PolarHBondContact O-N 3.27Å; N447-H449 PolarHBondContact O-N 2.91Å; H449-V452 PolarHBondContact O-N 2.76Å; H449-R453 WeakPolarHBondContact O-CB 3.38Å; H449-R453 VanDerWaalsContact O-CG 3.32Å; H449-R453 WeakPolarHBondContact O-CG 3.35Å; H449-R453 PolarHBondContact O-N 3.48Å; H449-S511 PolarHBondContact ND1-O 2.76Å; H449-V514 PolarHBondContact CE1-N 3.1Å; H449-H515 AromaticContact CE1-ND1 3.9Å; H449-H515 AromaticContact NE2-ND1 3.25Å; H449-H515 PolarHBondContact NE2-ND1 3.13Å
450	R	92	Very high	88.3	Confident	171 Å²	171	61.3 Å²	61.3	65%	0.645	30%	0.297	S	S	*	.	H	α-helix	trans	-64	-39.9	175.4	-75.3	-171.5	-70.1	163.8	-7.2	112.1	G446 N447 C448 G454	G446-R450 WeakPolarHBondContact O-CG 3.33Å; G446-R450 PolarHBondContact O-N 3.22Å; G446-R450 VanDerWaalsContact O-N 3.14Å; N447-R450 WeakPolarHBondContact O-CB 3.19Å; N447-R450 PolarHBondContact O-N 3.23Å; N447-R450 VanDerWaalsContact O-N 3.17Å; N447-R450 PolarHBondContact OD1-NH2 3.45Å; C448-R450 VanDerWaalsContact C-N 3.3Å; C448-R450 PolarHBondContact O-N 3.35Å; R450-G454 WeakPolarHBondContact O-CA 3.42Å; R450-G454 PolarHBondContact O-N 3.32Å
451	V	91.1	Very high	88.9	Confident	65 Å²	65	61.4 Å²	61.4	39%	0.394	30%	0.298	S	S	.	.	H	α-helix	trans	-65	-49.1	176.1	171.8	0	0	0	0	111.1	N447 C448 R453 G454 A455 T567 A571	N447-V451 WeakPolarHBondContact O-CG2 3.5Å; N447-V451 PolarHBondContact O-N 3.1Å; C448-V451 PolarHBondContact O-N 3.11Å; V451-R453 PolarHBondContact O-N 3Å; V451-G454 PolarHBondContact O-N 3.27Å; V451-A455 VanDerWaalsContact O-CB 3.28Å; V451-A455 WeakPolarHBondContact O-CB 3.42Å; V451-A455 PolarHBondContact O-N 3.12Å; V451-T567 HydrophobicContact CG1-CG2 3.5Å; V451-A571 HydrophobicContact CB-CB 4.3Å; V451-A571 HydrophobicContact CG1-CB 3.95Å
452	V	89.1	Confident	89.7	Confident	0 Å²	0	59.1 Å²	59.1	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-57.7	-49.6	178.2	172.7	0	0	0	0	110.8	C448 H449 A456 I568 A571 L575	C448-V452 WeakPolarHBondContact O-CG2 3.29Å; C448-V452 PolarHBondContact O-N 2.88Å; H449-V452 PolarHBondContact O-N 2.76Å; V452-A456 WeakPolarHBondContact O-CB 3.48Å; V452-A456 PolarHBondContact O-N 2.98Å; V452-I568 HydrophobicContact CG1-CG2 4.42Å; V452-A571 HydrophobicContact CG2-CB 3.54Å; V452-L575 HydrophobicContact CG2-CD1 4.32Å
453	R	93.5	Very high	90.2	Very high	99 Å²	99	55.1 Å²	55.1	37%	0.374	26%	0.264	S	S	.	.	H	α-helix	trans	-66.5	-42.3	179.4	-71	179	175.5	173.5	1.2	112.4	H449 V451 A456 W457 L508 S511 N512	H449-R453 WeakPolarHBondContact O-CB 3.38Å; H449-R453 VanDerWaalsContact O-CG 3.32Å; H449-R453 WeakPolarHBondContact O-CG 3.35Å; H449-R453 PolarHBondContact O-N 3.48Å; V451-R453 PolarHBondContact O-N 3Å; R453-A456 PolarHBondContact O-N 3.18Å; R453-W457 WeakPolarHBondContact O-CB 3.47Å; R453-W457 PolarHBondContact O-N 3.39Å; R453-L508 HydrophobicContact CB-CD1 4.13Å; R453-L508 HydrophobicContact CG-CD1 3.99Å; R453-S511 WeakPolarHBondContact CG-OG 3.34Å; R453-S511 PolarHBondContact NE-OG 3.5Å; R453-N512 PolarHBondContact NH2-OD1 3.34Å
454	G	92.7	Very high	90.6	Very high	38 Å²	38	50 Å²	50	39%	0.392	25%	0.25	S	C	.	.	H	α-helix	trans	-63.2	-44.4	178.9	0	0	0	0	0	112	R450 V451 W457 A458	R450-G454 WeakPolarHBondContact O-CA 3.42Å; R450-G454 PolarHBondContact O-N 3.32Å; V451-G454 PolarHBondContact O-N 3.27Å; G454-W457 PolarHBondContact O-N 3.41Å; G454-A458 WeakPolarHBondContact O-CB 3.28Å; G454-A458 PolarHBondContact O-N 3.31Å
455	A	92.7	Very high	91.1	Very high	7 Å²	7	50 Å²	50	6%	0.058	26%	0.258	C	S	.	.	H	α-helix	trans	-64	-42.8	175.5	0	0	0	0	0	111.8	V451 A458 Q459 L564 I568	V451-A455 VanDerWaalsContact O-CB 3.28Å; V451-A455 WeakPolarHBondContact O-CB 3.42Å; V451-A455 PolarHBondContact O-N 3.12Å; A455-A458 PolarHBondContact O-N 3.48Å; A455-Q459 WeakPolarHBondContact O-CG 3.43Å; A455-Q459 PolarHBondContact O-N 2.85Å; A455-L564 HydrophobicContact CB-CD2 4.16Å; A455-I568 HydrophobicContact CB-CD1 3.99Å; A455-I568 HydrophobicContact CB-CG1 3.63Å
456	A	92.4	Very high	91.3	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-63	-44.2	176.3	0	0	0	0	0	112.3	V452 R453 Q459 I460 P504 L508	V452-A456 WeakPolarHBondContact O-CB 3.48Å; V452-A456 PolarHBondContact O-N 2.98Å; R453-A456 PolarHBondContact O-N 3.18Å; A456-Q459 PolarHBondContact O-N 3.47Å; A456-I460 WeakPolarHBondContact O-CG1 3.49Å; A456-I460 PolarHBondContact O-N 3.02Å; A456-P504 HydrophobicContact CB-CB 4.41Å; A456-P504 WeakPolarHBondContact O-CB 3.44Å; A456-L508 HydrophobicContact CB-CB 4.16Å; A456-L508 HydrophobicContact CB-CD1 4.47Å
457	W	94.7	Very high	91.4	Very high	142 Å²	142	52.2 Å²	52.2	54%	0.538	26%	0.257	S	S	.	.	H	α-helix	trans	-62.7	-41.9	174.5	-85	117.2	0	0	0	112.7	R453 G454 Q459 I460 M461 L508	R453-W457 WeakPolarHBondContact O-CB 3.47Å; R453-W457 PolarHBondContact O-N 3.39Å; G454-W457 PolarHBondContact O-N 3.41Å; W457-Q459 VanDerWaalsContact C-N 3.3Å; W457-Q459 PolarHBondContact O-N 3.45Å; W457-I460 HydrophobicContact CE3-CD1 4.08Å; W457-I460 HydrophobicContact CE3-CG2 4.46Å; W457-I460 HydrophobicContact CZ3-CD1 4.33Å; W457-I460 PolarHBondContact O-N 2.59Å; W457-M461 WeakPolarHBondContact O-CG 3.5Å; W457-M461 PolarHBondContact O-N 3.44Å; W457-L508 HydrophobicContact CD2-CD2 4.02Å; W457-L508 VanDerWaalsContact CE2-CD2 3.49Å; W457-L508 HydrophobicContact CH2-CD2 4.19Å; W457-L508 HydrophobicContact CZ2-CD2 3.6Å
458	A	93.9	Very high	91.4	Very high	38 Å²	38	52.9 Å²	52.9	31%	0.314	27%	0.265	S	S	.	.	H	α-helix	trans	-59	-43.6	175.8	0	0	0	0	0	111.2	G454 A455 M461 I462 L564	G454-A458 WeakPolarHBondContact O-CB 3.28Å; G454-A458 PolarHBondContact O-N 3.31Å; A455-A458 PolarHBondContact O-N 3.48Å; A458-M461 PolarHBondContact O-N 2.83Å; A458-I462 WeakPolarHBondContact O-CD1 3.36Å; A458-I462 VanDerWaalsContact O-CG1 3.23Å; A458-I462 WeakPolarHBondContact O-CG1 3.44Å; A458-I462 PolarHBondContact O-N 3.3Å; A458-L564 HydrophobicContact CB-CD1 4.1Å; A458-L564 HydrophobicContact CB-CD2 4.45Å
459	Q	93.5	Very high	91.4	Very high	0 Å²	0	53.4 Å²	53.4	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-64.9	-40.8	176.6	-67.3	171.9	-22.9	0	0	112.8	A455 A456 W457 M461 I462 G463 L500 P504 T561 L564 Q565	A455-Q459 WeakPolarHBondContact O-CG 3.43Å; A455-Q459 PolarHBondContact O-N 2.85Å; A456-Q459 PolarHBondContact O-N 3.47Å; W457-Q459 VanDerWaalsContact C-N 3.3Å; W457-Q459 PolarHBondContact O-N 3.45Å; Q459-M461 VanDerWaalsContact C-N 3.3Å; Q459-M461 PolarHBondContact O-N 3.01Å; Q459-I462 PolarHBondContact O-N 3.01Å; Q459-G463 PolarHBondContact O-N 3.35Å; Q459-L500 CarbonylContact C-O 3.59Å; Q459-P504 HydrophobicContact CB-CB 3.71Å; Q459-P504 HydrophobicContact CB-CG 3.43Å; Q459-P504 VanDerWaalsContact CB-CG 3.43Å; Q459-P504 HydrophobicContact CG-CG 4.25Å; Q459-T561 HydrophobicContact CG-CG2 4.36Å; Q459-T561 PolarHBondContact NE2-O 2.73Å; Q459-L564 HydrophobicContact CG-CB 3.7Å; Q459-L564 HydrophobicContact CG-CD1 3.54Å; Q459-L564 HydrophobicContact CG-CG 4.25Å; Q459-Q565 VanDerWaalsContact NE2-CD 3.34Å; Q459-Q565 VanDerWaalsContact NE2-N 3.2Å; Q459-Q565 VanDerWaalsContact NE2-NE2 3.1Å
460	I	93.6	Very high	91	Very high	15 Å²	15	52.5 Å²	52.5	8%	0.077	26%	0.264	C	S	.	.	H	α-helix	trans	-56.1	-47.1	173.3	-70.3	169.8	0	0	0	110.5	A456 W457 I462 G463 I464 T501 P504 A505 L508	A456-I460 WeakPolarHBondContact O-CG1 3.49Å; A456-I460 PolarHBondContact O-N 3.02Å; W457-I460 HydrophobicContact CE3-CD1 4.08Å; W457-I460 HydrophobicContact CE3-CG2 4.46Å; W457-I460 HydrophobicContact CZ3-CD1 4.33Å; W457-I460 PolarHBondContact O-N 2.59Å; I460-I462 PolarHBondContact O-N 3.47Å; I460-G463 PolarHBondContact O-N 2.88Å; I460-I464 HydrophobicContact CG2-CD1 3.83Å; I460-I464 WeakPolarHBondContact O-CG1 3.5Å; I460-I464 PolarHBondContact O-N 2.85Å; I460-T501 HydrophobicContact CG2-CG2 4.21Å; I460-P504 HydrophobicContact CG1-CB 4.05Å; I460-A505 HydrophobicContact CD1-CB 4.27Å; I460-L508 HydrophobicContact CD1-CD2 4.05Å
461	M	93.5	Very high	90.4	Very high	117 Å²	117	48.1 Å²	48.1	58%	0.576	26%	0.256	S	S	*	.	H	α-helix	trans	-64.6	-39.9	179.1	-66.8	-55.2	-61.2	0	0	112.4	W457 A458 Q459 I464 L465	W457-M461 WeakPolarHBondContact O-CG 3.5Å; W457-M461 PolarHBondContact O-N 3.44Å; A458-M461 PolarHBondContact O-N 2.83Å; Q459-M461 VanDerWaalsContact C-N 3.3Å; Q459-M461 PolarHBondContact O-N 3.01Å; M461-I464 PolarHBondContact O-N 3.46Å; M461-L465 WeakPolarHBondContact O-CB 3.43Å; M461-L465 PolarHBondContact O-N 2.88Å
462	I	92.7	Very high	89.7	Confident	24 Å²	24	47.9 Å²	47.9	12%	0.123	27%	0.267	C	S	.	.	H	α-helix	trans	-61.2	-46.5	174	-68.6	158.9	0	0	0	110.3	A458 Q459 I460 I464 L465 V466 A557 L560 L564	A458-I462 WeakPolarHBondContact O-CD1 3.36Å; A458-I462 VanDerWaalsContact O-CG1 3.23Å; A458-I462 WeakPolarHBondContact O-CG1 3.44Å; A458-I462 PolarHBondContact O-N 3.3Å; Q459-I462 PolarHBondContact O-N 3.01Å; I460-I462 PolarHBondContact O-N 3.47Å; I462-I464 PolarHBondContact O-N 3.3Å; I462-L465 PolarHBondContact O-N 2.89Å; I462-V466 HydrophobicContact CG2-CG2 4.35Å; I462-V466 VanDerWaalsContact O-CG2 3.23Å; I462-V466 WeakPolarHBondContact O-CG2 3.33Å; I462-V466 PolarHBondContact O-N 2.94Å; I462-A557 HydrophobicContact CG2-CB 3.47Å; I462-A557 VanDerWaalsContact CG2-CB 3.47Å; I462-L560 HydrophobicContact CD1-CB 4.48Å; I462-L560 HydrophobicContact CD1-CD2 3.35Å; I462-L560 HydrophobicContact CD1-CG 3.69Å; I462-L560 HydrophobicContact CG1-CD2 4.01Å; I462-L564 HydrophobicContact CD1-CD1 3.54Å
463	G	90.8	Very high	88.8	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-60	-44.7	178.1	0	0	0	0	0	112.9	Q459 I460 V466 Y467	Q459-G463 PolarHBondContact O-N 3.35Å; I460-G463 PolarHBondContact O-N 2.88Å; G463-V466 PolarHBondContact O-N 3.36Å; G463-Y467 WeakPolarHBondContact O-CB 3.33Å; G463-Y467 PolarHBondContact O-N 3.49Å
464	I	91.9	Very high	87.4	Confident	77 Å²	77	56.8 Å²	56.8	40%	0.395	30%	0.303	S	S	.	.	H	α-helix	trans	-63.8	-43.9	175.5	-65.6	166.3	0	0	0	111.2	I460 M461 I462 V466 Y467 C468	I460-I464 HydrophobicContact CG2-CD1 3.83Å; I460-I464 WeakPolarHBondContact O-CG1 3.5Å; I460-I464 PolarHBondContact O-N 2.85Å; M461-I464 PolarHBondContact O-N 3.46Å; I462-I464 PolarHBondContact O-N 3.3Å; I464-V466 PolarHBondContact O-N 3.18Å; I464-Y467 WeakPolarHBondContact O-CB 3.33Å; I464-Y467 PolarHBondContact O-N 3.14Å; I464-C468 PolarHBondContact O-N 3.47Å; I464-C468 PolarHBondContact O-SG 3Å; I464-C468 VanDerWaalsContact O-SG 3.33Å
465	L	91	Very high	85.9	Confident	114 Å²	114	57.3 Å²	57.3	60%	0.597	30%	0.297	S	S	*	.	H	α-helix	trans	-60.5	-47.3	178.2	178.8	65.4	0	0	0	111.1	M461 I462 Y467 C468 V469	M461-L465 WeakPolarHBondContact O-CB 3.43Å; M461-L465 PolarHBondContact O-N 2.88Å; I462-L465 PolarHBondContact O-N 2.89Å; L465-Y467 VanDerWaalsContact C-N 3.32Å; L465-Y467 PolarHBondContact O-N 3.41Å; L465-C468 WeakPolarHBondContact O-CB 3.22Å; L465-C468 PolarHBondContact O-N 3.21Å; L465-V469 WeakPolarHBondContact O-CG2 3.49Å; L465-V469 PolarHBondContact O-N 2.83Å
466	V	88.6	Confident	84.2	Confident	6 Å²	6	64.1 Å²	64.1	4%	0.036	33%	0.333	C	S	.	.	H	α-helix	trans	-65.9	-36.3	178.3	176.3	0	0	0	0	111.4	I462 G463 I464 V469 S470 L500 M554 A557	I462-V466 HydrophobicContact CG2-CG2 4.35Å; I462-V466 VanDerWaalsContact O-CG2 3.23Å; I462-V466 WeakPolarHBondContact O-CG2 3.33Å; I462-V466 PolarHBondContact O-N 2.94Å; G463-V466 PolarHBondContact O-N 3.36Å; I464-V466 PolarHBondContact O-N 3.18Å; V466-V469 PolarHBondContact O-N 3.02Å; V466-S470 WeakPolarHBondContact O-CB 3.37Å; V466-S470 PolarHBondContact O-N 3.19Å; V466-S470 PolarHBondContact O-OG 3.43Å; V466-L500 HydrophobicContact CG2-CD1 4.42Å; V466-M554 HydrophobicContact CG1-CB 4.28Å; V466-M554 HydrophobicContact CG1-SD 3.53Å; V466-M554 VanDerWaalsContact CG1-SD 3.53Å; V466-A557 HydrophobicContact CG2-CB 3.27Å
467	Y	88.5	Confident	82.6	Confident	84 Å²	84	65.4 Å²	65.4	33%	0.329	35%	0.346	S	S	.	.	H	α-helix	trans	-58.4	-49.3	172.1	175.2	-92	0	0	0	110.9	G463 I464 L465 V469 S470 V471 T494 S497 F498	G463-Y467 WeakPolarHBondContact O-CB 3.33Å; G463-Y467 PolarHBondContact O-N 3.49Å; I464-Y467 WeakPolarHBondContact O-CB 3.33Å; I464-Y467 PolarHBondContact O-N 3.14Å; L465-Y467 VanDerWaalsContact C-N 3.32Å; L465-Y467 PolarHBondContact O-N 3.41Å; Y467-V469 VanDerWaalsContact C-N 3.33Å; Y467-V469 PolarHBondContact O-N 3.38Å; Y467-S470 WeakPolarHBondContact O-CB 3.1Å; Y467-S470 PolarHBondContact O-N 3.46Å; Y467-S470 VanDerWaalsContact O-N 3.12Å; Y467-V471 HydrophobicContact CD1-CG2 4.45Å; Y467-V471 HydrophobicContact CD2-CG2 4.43Å; Y467-V471 HydrophobicContact CE1-CG2 4.07Å; Y467-V471 HydrophobicContact CE2-CG2 4.04Å; Y467-V471 WeakPolarHBondContact O-CG2 3.38Å; Y467-V471 PolarHBondContact O-N 3.21Å; Y467-T494 HydrophobicContact CD2-CG2 3.65Å; Y467-T494 HydrophobicContact CE2-CG2 3.37Å; Y467-S497 WeakPolarHBondContact CA-OG 3.23Å; Y467-S497 WeakPolarHBondContact CB-OG 3.33Å; Y467-S497 WeakPolarHBondContact CD2-OG 3.42Å; Y467-F498 HydrophobicContact CD2-CE1 4.18Å; Y467-F498 HydrophobicContact CD2-CE2 4.09Å; Y467-F498 AromaticContact CD2-CZ 3.87Å; Y467-F498 HydrophobicContact CD2-CZ 3.87Å; Y467-F498 HydrophobicContact CE2-CE1 4.01Å; Y467-F498 AromaticContact CE2-CE2 3.66Å; Y467-F498 HydrophobicContact CE2-CE2 3.66Å; Y467-F498 AromaticContact CE2-CZ 3.33Å; Y467-F498 HydrophobicContact CE2-CZ 3.33Å
468	C	88.3	Confident	80.6	Confident	74 Å²	74	64.3 Å²	64.3	50%	0.5	36%	0.357	S	S	.	.	H	α-helix	trans	-59.5	-42.2	176.9	-68.6	0	0	0	0	112.2	I464 L465 G472	I464-C468 PolarHBondContact O-N 3.47Å; I464-C468 PolarHBondContact O-SG 3Å; I464-C468 VanDerWaalsContact O-SG 3.33Å; L465-C468 WeakPolarHBondContact O-CB 3.22Å; L465-C468 PolarHBondContact O-N 3.21Å; C468-G472 WeakPolarHBondContact O-CA 3.22Å; C468-G472 PolarHBondContact O-N 3.22Å
469	V	85.9	Confident	78.9	Confident	30 Å²	30	68.9 Å²	68.9	18%	0.182	38%	0.376	C	S	.	.	H	α-helix	trans	-64.5	-42.7	174.5	173.3	0	0	0	0	110.8	L465 V466 Y467 V471 G472 F473 A553	L465-V469 WeakPolarHBondContact O-CG2 3.49Å; L465-V469 PolarHBondContact O-N 2.83Å; V466-V469 PolarHBondContact O-N 3.02Å; Y467-V469 VanDerWaalsContact C-N 3.33Å; Y467-V469 PolarHBondContact O-N 3.38Å; V469-V471 VanDerWaalsContact C-N 3.31Å; V469-V471 PolarHBondContact O-N 2.95Å; V469-G472 PolarHBondContact O-N 2.89Å; V469-F473 HydrophobicContact CB-CD2 4.33Å; V469-F473 HydrophobicContact CG1-CD2 3.67Å; V469-F473 HydrophobicContact CG1-CE2 4.1Å; V469-F473 WeakPolarHBondContact O-CB 3.4Å; V469-F473 WeakPolarHBondContact O-CD2 3.19Å; V469-F473 PolarHBondContact O-N 3.37Å; V469-A553 HydrophobicContact CG1-CB 3.76Å
470	S	80.2	Confident	77.2	Confident	1 Å²	1	71.5 Å²	71.5	1%	0.007	39%	0.388	C	S	.	.	H	α-helix	trans	-65.9	-33.4	-177.3	-62.6	0	0	0	0	113.1	V466 Y467 R493	V466-S470 WeakPolarHBondContact O-CB 3.37Å; V466-S470 PolarHBondContact O-N 3.19Å; V466-S470 PolarHBondContact O-OG 3.43Å; Y467-S470 WeakPolarHBondContact O-CB 3.1Å; Y467-S470 PolarHBondContact O-N 3.46Å; Y467-S470 VanDerWaalsContact O-N 3.12Å; S470-R493 PolarHBondContact O-NH2 3.48Å; S470-R493 WeakPolarHBondContact OG-CG 2.98Å
471	V	80.7	Confident	75.9	Confident	79 Å²	79	76.7 Å²	76.7	48%	0.479	41%	0.412	S	S	.	.	H	α-helix	trans	-86.4	-38.4	176.4	176.5	0	0	0	0	111.5	Y467 V469 T494	Y467-V471 HydrophobicContact CD1-CG2 4.45Å; Y467-V471 HydrophobicContact CD2-CG2 4.43Å; Y467-V471 HydrophobicContact CE1-CG2 4.07Å; Y467-V471 HydrophobicContact CE2-CG2 4.04Å; Y467-V471 WeakPolarHBondContact O-CG2 3.38Å; Y467-V471 PolarHBondContact O-N 3.21Å; V469-V471 VanDerWaalsContact C-N 3.31Å; V469-V471 PolarHBondContact O-N 2.95Å; V471-T494 HydrophobicContact CG2-CG2 4.48Å
472	G	76.4	Confident	74.6	Confident	61 Å²	61	74 Å²	74	63%	0.629	40%	0.397	S	S	*	.	H	α-helix	trans	-76	-34.6	-175	0	0	0	0	0	114.2	C468 V469 R474	C468-G472 WeakPolarHBondContact O-CA 3.22Å; C468-G472 PolarHBondContact O-N 3.22Å; V469-G472 PolarHBondContact O-N 2.89Å; G472-R474 PolarHBondContact O-N 3.46Å
473	F	70.1	Confident	73.4	Confident	105 Å²	105	73 Å²	73	46%	0.461	39%	0.393	S	S	.	.			trans	-91.6	80.8	173.6	-69.6	-90.6	0	0	0	109.3	V469 R493 V549	V469-F473 HydrophobicContact CB-CD2 4.33Å; V469-F473 HydrophobicContact CG1-CD2 3.67Å; V469-F473 HydrophobicContact CG1-CE2 4.1Å; V469-F473 WeakPolarHBondContact O-CB 3.4Å; V469-F473 WeakPolarHBondContact O-CD2 3.19Å; V469-F473 PolarHBondContact O-N 3.37Å; F473-R493 PolarHBondContact O-NH2 3.14Å; F473-V549 HydrophobicContact CD1-CB 4.48Å; F473-V549 HydrophobicContact CD1-CG1 4.37Å; F473-V549 HydrophobicContact CE1-CG1 4.38Å
474	R	62.8	Low	72.2	Confident	180 Å²	180	75.2 Å²	75.2	68%	0.679	40%	0.404	S	S	*	.			trans	-81.8	112.5	167	-170.4	172.9	178.2	179.7	-4.1	107.6	G472 N476	G472-R474 PolarHBondContact O-N 3.46Å; R474-N476 PolarHBondContact O-N 3.33Å
475	D	61.7	Low	71.1	Confident	50 Å²	50	74 Å²	74	27%	0.267	40%	0.396	S	S	.	.			trans	-63.4	117.8	173.9	-59.4	-44.1	0	0	0	107.9	H480	D475-H480 VanDerWaalsContact CB-CE1 3.49Å; D475-H480 WeakPolarHBondContact CB-CE1 3.45Å; D475-H480 VanDerWaalsContact O-CB 3.23Å; D475-H480 WeakPolarHBondContact O-CB 3.48Å; D475-H480 PolarHBondContact O-CD2 3.25Å
476	N	57.7	Low	70.3	Confident	149 Å²	149	69.4 Å²	69.4	80%	0.797	37%	0.373	S	S	*	.			trans	-86.3	121.9	-177.3	-70.3	-34.5	0	0	0	109.2	R474	R474-N476 PolarHBondContact O-N 3.33Å
477	G	58.9	Low	69.5	Low	27 Å²	27	69.3 Å²	69.3	28%	0.278	37%	0.372	S	S	.	.	S	Bend	trans	165.2	157.2	174.7	0	0	0	0	0	112.8	L479 H480	G477-L479 VanDerWaalsContact C-N 3.27Å; G477-L479 PolarHBondContact O-N 2.86Å; G477-H480 WeakPolarHBondContact O-CA 3.36Å; G477-H480 WeakPolarHBondContact O-CB 3.22Å; G477-H480 PolarHBondContact O-N 3.47Å
478	P	52.9	Low	68.6	Low	119 Å²	119	68.3 Å²	68.3	77%	0.773	37%	0.37	S	S	*	.	G	3₁₀ helix	trans	-64.2	-31.1	-175.4	24.3	-33	0	0	0	112.8	H480 E481	P478-H480 PolarHBondContact O-N 3.4Å; P478-E481 PolarHBondContact O-N 3.08Å
479	L	56.2	Low	67.8	Low	134 Å²	134	66.6 Å²	66.6	70%	0.702	36%	0.356	S	S	*	.	G	3₁₀ helix	trans	-66.6	-27.7	173.7	-125.8	84.9	0	0	0	112.5	G477 E481 H482 F485	G477-L479 VanDerWaalsContact C-N 3.27Å; G477-L479 PolarHBondContact O-N 2.86Å; L479-E481 VanDerWaalsContact C-N 3.25Å; L479-E481 PolarHBondContact O-N 2.85Å; L479-H482 WeakPolarHBondContact O-CB 3.39Å; L479-H482 PolarHBondContact O-N 3.45Å; L479-F485 WeakPolarHBondContact O-CB 3.39Å
480	H	59.7	Low	67.5	Low	55 Å²	55	67.3 Å²	67.3	26%	0.255	36%	0.361	S	S	.	.	G	3₁₀ helix	trans	-80.2	-6	-179	-59.6	-60.6	0	0	0	113.2	D475 G477 P478 F485 V486	D475-H480 VanDerWaalsContact CB-CE1 3.49Å; D475-H480 WeakPolarHBondContact CB-CE1 3.45Å; D475-H480 VanDerWaalsContact O-CB 3.23Å; D475-H480 WeakPolarHBondContact O-CB 3.48Å; D475-H480 PolarHBondContact O-CD2 3.25Å; G477-H480 WeakPolarHBondContact O-CA 3.36Å; G477-H480 WeakPolarHBondContact O-CB 3.22Å; G477-H480 PolarHBondContact O-N 3.47Å; P478-H480 PolarHBondContact O-N 3.4Å; H480-F485 HydrophobicContact CB-CD1 4.26Å; H480-F485 HydrophobicContact CB-CE1 4.34Å; H480-F485 AromaticContact CE1-CE1 3.71Å; H480-F485 AromaticContact CE1-CE2 3.98Å; H480-F485 AromaticContact CE1-CZ 3.34Å; H480-F485 WeakPolarHBondContact CE1-CZ 3.33Å; H480-F485 AromaticContact CG-CE1 3.97Å; H480-F485 AromaticContact ND1-CD1 3.53Å; H480-F485 AromaticContact ND1-CE1 2.91Å; H480-F485 WeakPolarHBondContact ND1-CE1 2.85Å; H480-F485 AromaticContact ND1-CE2 3.72Å; H480-F485 AromaticContact ND1-CZ 3.01Å; H480-F485 WeakPolarHBondContact ND1-CZ 3.33Å; H480-V486 WeakPolarHBondContact O-CG2 3.36Å
481	E	65.5	Low	67.5	Low	125 Å²	125	67.8 Å²	67.8	58%	0.584	36%	0.363	S	S	*	.	G	3₁₀ helix	trans	-92.1	-11.4	172.4	-61.1	-172.2	162.4	0	0	112.5	Y370 P478 L479	Y370-E481 PolarHBondContact OH-O 3.37Å; P478-E481 PolarHBondContact O-N 3.08Å; L479-E481 VanDerWaalsContact C-N 3.25Å; L479-E481 PolarHBondContact O-N 2.85Å
482	H	65.9	Low	67.5	Low	59 Å²	59	66.6 Å²	66.6	27%	0.273	35%	0.352	S	S	.	.	S	Bend	trans	-63.9	129.6	177.2	-166.7	-76.7	0	0	0	109.9	F379 L479 L484 F485 V486	F379-H482 AromaticContact CE1-CE1 3.73Å; F379-H482 AromaticContact CZ-CE1 3.96Å; L479-H482 WeakPolarHBondContact O-CB 3.39Å; L479-H482 PolarHBondContact O-N 3.45Å; H482-L484 VanDerWaalsContact ND1-CB 3.35Å; H482-L484 WeakPolarHBondContact ND1-CB 3.35Å; H482-L484 PolarHBondContact ND1-N 3.3Å; H482-L484 PolarHBondContact O-N 2.97Å; H482-L484 VanDerWaalsContact O-N 3.12Å; H482-F485 HydrophobicContact CB-CB 4.3Å; H482-F485 WeakPolarHBondContact O-CB 3.26Å; H482-F485 PolarHBondContact O-N 3.03Å; H482-V486 PolarHBondContact O-N 3.31Å; H482-V486 VanDerWaalsContact O-N 3.07Å
483	P	67.5	Low	67.7	Low	4 Å²	4	63.7 Å²	63.7	3%	0.026	32%	0.322	C	S	.	.	H	α-helix	trans	-55.7	-38.7	-174.1	18	-31.2	0	0	0	112.5	Y364 L365 Y370 L378 F379 F485 V486 I487	Y364-P483 HydrophobicContact CE1-CB 4.41Å; L365-P483 HydrophobicContact CD2-CB 4.19Å; Y370-P483 HydrophobicContact CD1-CB 4.24Å; Y370-P483 HydrophobicContact CD1-CG 3.96Å; Y370-P483 HydrophobicContact CD2-CB 3.98Å; Y370-P483 HydrophobicContact CE1-CB 3.97Å; Y370-P483 HydrophobicContact CE1-CG 3.6Å; Y370-P483 HydrophobicContact CE2-CB 3.67Å; Y370-P483 HydrophobicContact CE2-CG 4.25Å; Y370-P483 HydrophobicContact CG-CB 4.26Å; Y370-P483 HydrophobicContact CG-CG 4.46Å; L378-P483 HydrophobicContact CD2-CG 3.84Å; F379-P483 HydrophobicContact CE2-CG 4.26Å; F379-P483 HydrophobicContact CZ-CG 3.98Å; P483-F485 VanDerWaalsContact C-N 3.34Å; P483-F485 PolarHBondContact O-N 3.13Å; P483-V486 PolarHBondContact O-N 3.12Å; P483-I487 WeakPolarHBondContact O-CB 3.32Å; P483-I487 WeakPolarHBondContact O-CG1 3.39Å; P483-I487 PolarHBondContact O-N 3.34Å
484	L	65.4	Low	68.4	Low	46 Å²	46	59.6 Å²	59.6	24%	0.241	31%	0.306	C	S	.	.	H	α-helix	trans	-57.4	-46.4	173.9	-73	175.6	0	0	0	114.2	F309 F379 H482 V486 I487 H488	F309-L484 HydrophobicContact CB-CD2 4.34Å; F309-L484 HydrophobicContact CD1-CD1 4.42Å; F309-L484 HydrophobicContact CD1-CD2 2.89Å; F309-L484 HydrophobicContact CD1-CG 4.08Å; F309-L484 HydrophobicContact CE1-CD1 3.86Å; F309-L484 HydrophobicContact CE1-CD2 3.18Å; F309-L484 HydrophobicContact CE1-CG 3.93Å; F309-L484 HydrophobicContact CG-CD2 3.77Å; F309-L484 HydrophobicContact CZ-CD2 4.32Å; F379-L484 HydrophobicContact CD1-CD1 4.05Å; F379-L484 HydrophobicContact CD1-CG 4.49Å; F379-L484 HydrophobicContact CE1-CD1 3.46Å; F379-L484 VanDerWaalsContact CE1-CD1 3.46Å; F379-L484 HydrophobicContact CE1-CD2 3.96Å; F379-L484 HydrophobicContact CE1-CG 3.45Å; F379-L484 VanDerWaalsContact CE1-CG 3.45Å; F379-L484 HydrophobicContact CZ-CD1 4.46Å; F379-L484 HydrophobicContact CZ-CD2 4.49Å; F379-L484 HydrophobicContact CZ-CG 4.02Å; H482-L484 VanDerWaalsContact ND1-CB 3.35Å; H482-L484 WeakPolarHBondContact ND1-CB 3.35Å; H482-L484 PolarHBondContact ND1-N 3.3Å; H482-L484 PolarHBondContact O-N 2.97Å; H482-L484 VanDerWaalsContact O-N 3.12Å; L484-V486 VanDerWaalsContact C-N 3.3Å; L484-I487 PolarHBondContact O-N 2.91Å; L484-H488 WeakPolarHBondContact O-CB 3.19Å; L484-H488 PolarHBondContact O-N 3.02Å
485	F	68.6	Low	69.5	Low	52 Å²	52	51 Å²	51	23%	0.228	27%	0.273	C	S	.	.	H	α-helix	trans	-64.7	-44.7	-177.6	-171	-77.6	0	0	0	108.6	L479 H480 H482 P483 I487 N489	L479-F485 WeakPolarHBondContact O-CB 3.39Å; H480-F485 HydrophobicContact CB-CD1 4.26Å; H480-F485 HydrophobicContact CB-CE1 4.34Å; H480-F485 AromaticContact CE1-CE1 3.71Å; H480-F485 AromaticContact CE1-CE2 3.98Å; H480-F485 AromaticContact CE1-CZ 3.34Å; H480-F485 WeakPolarHBondContact CE1-CZ 3.33Å; H480-F485 AromaticContact CG-CE1 3.97Å; H480-F485 AromaticContact ND1-CD1 3.53Å; H480-F485 AromaticContact ND1-CE1 2.91Å; H480-F485 WeakPolarHBondContact ND1-CE1 2.85Å; H480-F485 AromaticContact ND1-CE2 3.72Å; H480-F485 AromaticContact ND1-CZ 3.01Å; H480-F485 WeakPolarHBondContact ND1-CZ 3.33Å; H482-F485 HydrophobicContact CB-CB 4.3Å; H482-F485 WeakPolarHBondContact O-CB 3.26Å; H482-F485 PolarHBondContact O-N 3.03Å; P483-F485 VanDerWaalsContact C-N 3.34Å; P483-F485 PolarHBondContact O-N 3.13Å; F485-I487 PolarHBondContact O-N 3.43Å; F485-N489 HydrophobicContact CD1-CB 4.06Å; F485-N489 WeakPolarHBondContact CD2-ND2 3.45Å; F485-N489 HydrophobicContact CE1-CB 3.64Å; F485-N489 VanDerWaalsContact CE1-ND2 3.35Å; F485-N489 WeakPolarHBondContact CE1-ND2 3.26Å; F485-N489 WeakPolarHBondContact CE2-ND2 2.91Å; F485-N489 HydrophobicContact CZ-CB 4.02Å; F485-N489 WeakPolarHBondContact CZ-ND2 3.47Å; F485-N489 WeakPolarHBondContact O-CA 3.38Å; F485-N489 VanDerWaalsContact O-CB 3.22Å; F485-N489 WeakPolarHBondContact O-CB 3.44Å; F485-N489 PolarHBondContact O-N 3.43Å
486	V	74.2	Confident	70.5	Confident	17 Å²	17	48.6 Å²	48.6	10%	0.103	26%	0.261	C	S	.	.	I	π-helix	trans	-63.4	-42.5	178.2	-178.5	0	0	0	0	111.7	Y364 H480 H482 P483 L484 T490 I491	Y364-V486 HydrophobicContact CD2-CG1 4.3Å; Y364-V486 HydrophobicContact CE1-CB 4.11Å; Y364-V486 HydrophobicContact CE1-CG1 4.01Å; Y364-V486 HydrophobicContact CE2-CB 4.4Å; Y364-V486 HydrophobicContact CE2-CG1 3.63Å; Y364-V486 VanDerWaalsContact CZ-CG1 3.48Å; Y364-V486 WeakPolarHBondContact OH-CB 3.18Å; Y364-V486 WeakPolarHBondContact OH-CG2 3.25Å; H480-V486 WeakPolarHBondContact O-CG2 3.36Å; H482-V486 PolarHBondContact O-N 3.31Å; H482-V486 VanDerWaalsContact O-N 3.07Å; P483-V486 PolarHBondContact O-N 3.12Å; L484-V486 VanDerWaalsContact C-N 3.3Å; V486-T490 CarbonylContact O-C 3.56Å; V486-T490 WeakPolarHBondContact O-CA 3.4Å; V486-T490 VanDerWaalsContact O-CB 3.28Å; V486-T490 WeakPolarHBondContact O-CB 3.25Å; V486-T490 PolarHBondContact O-N 3.21Å; V486-I491 HydrophobicContact CG1-CD1 4.47Å; V486-I491 HydrophobicContact CG1-CG1 4.4Å; V486-I491 PolarHBondContact O-N 3.34Å
487	I	72.7	Confident	71.9	Confident	5 Å²	5	41.5 Å²	41.5	3%	0.026	22%	0.223	C	C	.	.	I	π-helix	trans	-63.9	-51.6	178.6	-68.9	168.1	0	0	0	111	F357 T361 Y364 L365 P483 L484 F485 I491 H492	F357-I487 HydrophobicContact CZ-CG2 3.86Å; T361-I487 HydrophobicContact CG2-CB 4.44Å; T361-I487 HydrophobicContact CG2-CD1 3.5Å; T361-I487 VanDerWaalsContact CG2-CD1 3.5Å; T361-I487 HydrophobicContact CG2-CG1 3.61Å; T361-I487 HydrophobicContact CG2-CG2 3.96Å; Y364-I487 HydrophobicContact CD1-CG1 4.3Å; Y364-I487 HydrophobicContact CE1-CG1 4.48Å; L365-I487 HydrophobicContact CD1-CD1 4.25Å; L365-I487 HydrophobicContact CD2-CD1 3.88Å; L365-I487 HydrophobicContact CG-CD1 4.15Å; P483-I487 WeakPolarHBondContact O-CB 3.32Å; P483-I487 WeakPolarHBondContact O-CG1 3.39Å; P483-I487 PolarHBondContact O-N 3.34Å; L484-I487 PolarHBondContact O-N 2.91Å; F485-I487 PolarHBondContact O-N 3.43Å; I487-I491 HydrophobicContact CG1-CD1 4.11Å; I487-H492 WeakPolarHBondContact O-CB 3.1Å; I487-H492 PolarHBondContact O-N 3.26Å
488	H	69.3	Low	73.2	Confident	63 Å²	63	43.3 Å²	43.3	29%	0.292	22%	0.223	S	C	.	.	I	π-helix	trans	-79.9	-26.9	-174.5	-71.7	-33.2	0	0	0	114.6	F309 L484 H492	F309-H488 PolarHBondContact O-CE1 3.46Å; L484-H488 WeakPolarHBondContact O-CB 3.19Å; L484-H488 PolarHBondContact O-N 3.02Å; H488-H492 VanDerWaalsContact O-CB 3.31Å; H488-H492 WeakPolarHBondContact O-CB 3.34Å
489	N	72.6	Confident	74.8	Confident	37 Å²	37	37.7 Å²	37.7	20%	0.198	19%	0.186	C	C	.	.	I	π-helix	trans	-103.6	-36.9	-179.3	-71.4	-51	0	0	0	113.9	F485 R493 W551	F485-N489 HydrophobicContact CD1-CB 4.06Å; F485-N489 WeakPolarHBondContact CD2-ND2 3.45Å; F485-N489 HydrophobicContact CE1-CB 3.64Å; F485-N489 VanDerWaalsContact CE1-ND2 3.35Å; F485-N489 WeakPolarHBondContact CE1-ND2 3.26Å; F485-N489 WeakPolarHBondContact CE2-ND2 2.91Å; F485-N489 HydrophobicContact CZ-CB 4.02Å; F485-N489 WeakPolarHBondContact CZ-ND2 3.47Å; F485-N489 WeakPolarHBondContact O-CA 3.38Å; F485-N489 VanDerWaalsContact O-CB 3.22Å; F485-N489 WeakPolarHBondContact O-CB 3.44Å; F485-N489 PolarHBondContact O-N 3.43Å; N489-R493 WeakPolarHBondContact O-CB 3.44Å; N489-W551 PolarHBondContact OD1-NE1 3.35Å
490	T	77.7	Confident	76.3	Confident	45 Å²	45	31.4 Å²	31.4	28%	0.276	15%	0.153	S	C	.	.	I	π-helix	trans	-98	-55.8	-175.9	-51.9	0	0	0	0	111.1	V486 R493 T494	V486-T490 CarbonylContact O-C 3.56Å; V486-T490 WeakPolarHBondContact O-CA 3.4Å; V486-T490 VanDerWaalsContact O-CB 3.28Å; V486-T490 WeakPolarHBondContact O-CB 3.25Å; V486-T490 PolarHBondContact O-N 3.21Å; T490-R493 PolarHBondContact O-N 3.32Å; T490-T494 VanDerWaalsContact O-CB 3.24Å; T490-T494 WeakPolarHBondContact O-CB 3.41Å; T490-T494 PolarHBondContact O-N 3.49Å; T490-T494 PolarHBondContact O-OG1 3.11Å
491	I	81.8	Confident	77.8	Confident	12 Å²	12	30.3 Å²	30.3	6%	0.062	15%	0.15	C	C	.	.	I	π-helix	trans	-68.2	-44.8	-176.7	-61.8	177	0	0	0	110.4	F357 I360 Y364 V486 I487 T494 T495	F357-I491 HydrophobicContact CD2-CG2 4.04Å; F357-I491 HydrophobicContact CE2-CG2 3.95Å; I360-I491 HydrophobicContact CB-CG2 4.3Å; I360-I491 HydrophobicContact CG2-CD1 4.5Å; I360-I491 HydrophobicContact CG2-CG1 4.46Å; I360-I491 HydrophobicContact CG2-CG2 3.69Å; Y364-I491 HydrophobicContact CD1-CD1 3.87Å; Y364-I491 HydrophobicContact CD2-CD1 4.28Å; Y364-I491 HydrophobicContact CG-CD1 3.65Å; V486-I491 HydrophobicContact CG1-CD1 4.47Å; V486-I491 HydrophobicContact CG1-CG1 4.4Å; V486-I491 PolarHBondContact O-N 3.34Å; I487-I491 HydrophobicContact CG1-CD1 4.11Å; I491-T494 PolarHBondContact O-N 3.03Å; I491-T495 HydrophobicContact CG2-CG2 4.3Å; I491-T495 WeakPolarHBondContact O-CB 3.31Å; I491-T495 VanDerWaalsContact O-CG2 3.29Å; I491-T495 WeakPolarHBondContact O-CG2 3.41Å; I491-T495 PolarHBondContact O-N 3.02Å; I491-T495 PolarHBondContact O-OG1 2.88Å
492	H	79.4	Confident	78.9	Confident	53 Å²	53	25.9 Å²	25.9	25%	0.245	13%	0.13	C	C	.	.	H	α-helix	trans	-61	-48	176.3	-172.5	45.4	0	0	0	111.7	F357 I487 H488 T494 T495 L496 W551	F357-H492 HydrophobicContact CE2-CB 3.93Å; I487-H492 WeakPolarHBondContact O-CB 3.1Å; I487-H492 PolarHBondContact O-N 3.26Å; H488-H492 VanDerWaalsContact O-CB 3.31Å; H488-H492 WeakPolarHBondContact O-CB 3.34Å; H492-T494 VanDerWaalsContact C-N 3.34Å; H492-T494 PolarHBondContact O-N 3.35Å; H492-T495 WeakPolarHBondContact CA-OG1 3.46Å; H492-T495 PolarHBondContact O-N 3.12Å; H492-T495 PolarHBondContact O-OG1 3.26Å; H492-L496 WeakPolarHBondContact O-CB 3.26Å; H492-L496 VanDerWaalsContact O-CG 3.27Å; H492-L496 WeakPolarHBondContact O-CG 3.45Å; H492-L496 PolarHBondContact O-N 3.03Å; H492-W551 AromaticContact CD2-CH2 3.79Å
493	R	81.9	Confident	80	Confident	1 Å²	1	23 Å²	23	0%	0.004	12%	0.117	C	C	.	.	H	α-helix	trans	-59.7	-42.9	175.3	-175.2	178.1	65.2	-158.8	7.9	112.6	S470 F473 N489 T490 L496 S497 W551	S470-R493 PolarHBondContact O-NH2 3.48Å; S470-R493 WeakPolarHBondContact OG-CG 2.98Å; F473-R493 PolarHBondContact O-NH2 3.14Å; N489-R493 WeakPolarHBondContact O-CB 3.44Å; T490-R493 PolarHBondContact O-N 3.32Å; R493-L496 PolarHBondContact O-N 3.03Å; R493-S497 PolarHBondContact O-N 3.22Å; R493-W551 HydrophobicContact CB-CH2 4.44Å; R493-W551 HydrophobicContact CB-CZ2 4.45Å
494	T	84.2	Confident	81.1	Confident	18 Å²	18	22.9 Å²	22.9	11%	0.11	12%	0.117	C	C	.	.	H	α-helix	trans	-64.4	-43.2	178.4	-56.6	0	0	0	0	111.3	Y467 V471 T490 I491 H492 S497 F498	Y467-T494 HydrophobicContact CD2-CG2 3.65Å; Y467-T494 HydrophobicContact CE2-CG2 3.37Å; V471-T494 HydrophobicContact CG2-CG2 4.48Å; T490-T494 VanDerWaalsContact O-CB 3.24Å; T490-T494 WeakPolarHBondContact O-CB 3.41Å; T490-T494 PolarHBondContact O-N 3.49Å; T490-T494 PolarHBondContact O-OG1 3.11Å; I491-T494 PolarHBondContact O-N 3.03Å; H492-T494 VanDerWaalsContact C-N 3.34Å; H492-T494 PolarHBondContact O-N 3.35Å; T494-S497 PolarHBondContact O-N 3.3Å; T494-S497 PolarHBondContact O-OG 3.36Å; T494-F498 HydrophobicContact CG2-CD2 4.33Å; T494-F498 HydrophobicContact CG2-CE2 3.9Å; T494-F498 VanDerWaalsContact O-CD2 3.26Å; T494-F498 WeakPolarHBondContact O-CD2 3.36Å; T494-F498 PolarHBondContact O-N 2.77Å; T494-F498 VanDerWaalsContact O-N 3.07Å
495	T	85.5	Confident	82.3	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-67.5	-35.6	177	52.3	0	0	0	0	112.9	M356 F357 I360 I491 H492 F498 M499	M356-T495 HydrophobicContact CE-CG2 3.95Å; F357-T495 HydrophobicContact CB-CG2 3.99Å; F357-T495 HydrophobicContact CD2-CG2 3.94Å; F357-T495 WeakPolarHBondContact CD2-OG1 3.27Å; F357-T495 HydrophobicContact CG-CG2 4.45Å; I360-T495 HydrophobicContact CD1-CG2 3.93Å; I491-T495 HydrophobicContact CG2-CG2 4.3Å; I491-T495 WeakPolarHBondContact O-CB 3.31Å; I491-T495 VanDerWaalsContact O-CG2 3.29Å; I491-T495 WeakPolarHBondContact O-CG2 3.41Å; I491-T495 PolarHBondContact O-N 3.02Å; I491-T495 PolarHBondContact O-OG1 2.88Å; H492-T495 WeakPolarHBondContact CA-OG1 3.46Å; H492-T495 PolarHBondContact O-N 3.12Å; H492-T495 PolarHBondContact O-OG1 3.26Å; T495-F498 WeakPolarHBondContact O-CB 3.41Å; T495-F498 PolarHBondContact O-N 2.82Å; T495-M499 PolarHBondContact O-N 3.32Å; T495-M499 VanDerWaalsContact O-N 3.12Å
496	L	83.5	Confident	83.3	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-65.5	-37.8	170.1	-69.6	176.9	0	0	0	112.6	H492 R493 F498 M499 L500 W551 M554	H492-L496 WeakPolarHBondContact O-CB 3.26Å; H492-L496 VanDerWaalsContact O-CG 3.27Å; H492-L496 WeakPolarHBondContact O-CG 3.45Å; H492-L496 PolarHBondContact O-N 3.03Å; R493-L496 PolarHBondContact O-N 3.03Å; L496-F498 VanDerWaalsContact C-N 3.27Å; L496-F498 PolarHBondContact O-N 3.29Å; L496-M499 VanDerWaalsContact O-CB 3.25Å; L496-M499 WeakPolarHBondContact O-CB 3.23Å; L496-M499 PolarHBondContact O-N 3.45Å; L496-L500 PolarHBondContact O-N 3.41Å; L496-W551 HydrophobicContact CD1-CH2 4.28Å; L496-W551 HydrophobicContact CD1-CZ3 4.16Å; L496-M554 HydrophobicContact CB-CE 3.55Å; L496-M554 HydrophobicContact CB-SD 4.21Å
497	S	86.1	Confident	84.1	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-63.8	-33.6	173.5	77.3	0	0	0	0	112.3	Y467 R493 T494 M499 L500 T501	Y467-S497 WeakPolarHBondContact CA-OG 3.23Å; Y467-S497 WeakPolarHBondContact CB-OG 3.33Å; Y467-S497 WeakPolarHBondContact CD2-OG 3.42Å; R493-S497 PolarHBondContact O-N 3.22Å; T494-S497 PolarHBondContact O-N 3.3Å; T494-S497 PolarHBondContact O-OG 3.36Å; S497-M499 VanDerWaalsContact C-N 3.34Å; S497-M499 PolarHBondContact O-N 3Å; S497-L500 WeakPolarHBondContact O-CB 3.44Å; S497-L500 PolarHBondContact O-N 3.01Å; S497-T501 PolarHBondContact O-OG1 3.01Å
498	F	87.8	Confident	85	Confident	64 Å²	64	21 Å²	21	28%	0.281	12%	0.115	S	C	.	.	H	α-helix	trans	-64.1	-37.4	169.9	-76.2	-60.7	0	0	0	111.6	M356 Y467 T494 T495 L496 L500 T501 I502	M356-F498 HydrophobicContact CE-CB 3.49Å; M356-F498 VanDerWaalsContact CE-CB 3.49Å; M356-F498 HydrophobicContact CE-CD2 3.78Å; M356-F498 HydrophobicContact CE-CG 3.94Å; M356-F498 HydrophobicContact SD-CB 4.08Å; M356-F498 HydrophobicContact SD-CD2 3.95Å; M356-F498 HydrophobicContact SD-CG 4.07Å; Y467-F498 HydrophobicContact CD2-CE1 4.18Å; Y467-F498 HydrophobicContact CD2-CE2 4.09Å; Y467-F498 AromaticContact CD2-CZ 3.87Å; Y467-F498 HydrophobicContact CD2-CZ 3.87Å; Y467-F498 HydrophobicContact CE2-CE1 4.01Å; Y467-F498 AromaticContact CE2-CE2 3.66Å; Y467-F498 HydrophobicContact CE2-CE2 3.66Å; Y467-F498 AromaticContact CE2-CZ 3.33Å; Y467-F498 HydrophobicContact CE2-CZ 3.33Å; T494-F498 HydrophobicContact CG2-CD2 4.33Å; T494-F498 HydrophobicContact CG2-CE2 3.9Å; T494-F498 VanDerWaalsContact O-CD2 3.26Å; T494-F498 WeakPolarHBondContact O-CD2 3.36Å; T494-F498 PolarHBondContact O-N 2.77Å; T494-F498 VanDerWaalsContact O-N 3.07Å; T495-F498 WeakPolarHBondContact O-CB 3.41Å; T495-F498 PolarHBondContact O-N 2.82Å; L496-F498 VanDerWaalsContact C-N 3.27Å; L496-F498 PolarHBondContact O-N 3.29Å; F498-L500 VanDerWaalsContact C-N 3.29Å; F498-L500 PolarHBondContact O-N 2.87Å; F498-T501 CarbonylContact O-C 3.55Å; F498-T501 WeakPolarHBondContact O-CA 3.45Å; F498-T501 WeakPolarHBondContact O-CB 3.28Å; F498-T501 PolarHBondContact O-N 2.74Å; F498-I502 HydrophobicContact CB-CD1 3.84Å; F498-I502 WeakPolarHBondContact O-CD1 3.28Å; F498-I502 WeakPolarHBondContact O-CG1 3.31Å; F498-I502 PolarHBondContact O-N 3.11Å
499	M	86.4	Confident	86	Confident	2 Å²	2	23.7 Å²	23.7	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-59.4	-39.2	175.2	-68.1	-71.5	-117.3	0	0	113.1	F350 H353 T495 L496 S497 T501 I502 F503	F350-M499 HydrophobicContact CD1-CE 4.03Å; F350-M499 HydrophobicContact CE1-CE 4.23Å; H353-M499 HydrophobicContact CB-CE 3.32Å; H353-M499 HydrophobicContact CB-CG 4.39Å; H353-M499 HydrophobicContact CB-SD 3.25Å; H353-M499 WeakPolarHBondContact CB-SD 3.17Å; H353-M499 WeakPolarHBondContact CD2-CG 3.28Å; H353-M499 PolarHBondContact CD2-SD 2.85Å; H353-M499 WeakPolarHBondContact ND1-CE 3.31Å; H353-M499 VanDerWaalsContact NE2-CG 3.33Å; H353-M499 WeakPolarHBondContact NE2-CG 3.32Å; T495-M499 PolarHBondContact O-N 3.32Å; T495-M499 VanDerWaalsContact O-N 3.12Å; L496-M499 VanDerWaalsContact O-CB 3.25Å; L496-M499 WeakPolarHBondContact O-CB 3.23Å; L496-M499 PolarHBondContact O-N 3.45Å; S497-M499 VanDerWaalsContact C-N 3.34Å; S497-M499 PolarHBondContact O-N 3Å; M499-T501 PolarHBondContact O-N 3.19Å; M499-T501 VanDerWaalsContact O-N 3.14Å; M499-I502 PolarHBondContact O-N 2.9Å; M499-F503 HydrophobicContact CB-CD2 4.45Å; M499-F503 HydrophobicContact CE-CD2 4.49Å; M499-F503 HydrophobicContact CE-CE2 3.53Å; M499-F503 HydrophobicContact CE-CZ 4.27Å; M499-F503 PolarHBondContact O-N 3.46Å; M499-F503 HydrophobicContact SD-CD2 3.85Å; M499-F503 HydrophobicContact SD-CE2 3.39Å; M499-F503 WeakPolarHBondContact SD-CE2 3.38Å
500	L	86.9	Confident	86.7	Confident	1 Å²	1	22.2 Å²	22.2	1%	0.005	12%	0.123	C	C	.	.	H	α-helix	trans	-62.4	-14.8	173.6	-62.8	-179.8	0	0	0	112.6	Q459 V466 L496 S497 F498 P504 M554 A557 E558 T561	Q459-L500 CarbonylContact C-O 3.59Å; V466-L500 HydrophobicContact CG2-CD1 4.42Å; L496-L500 PolarHBondContact O-N 3.41Å; S497-L500 WeakPolarHBondContact O-CB 3.44Å; S497-L500 PolarHBondContact O-N 3.01Å; F498-L500 VanDerWaalsContact C-N 3.29Å; F498-L500 PolarHBondContact O-N 2.87Å; L500-P504 WeakPolarHBondContact O-CD 3.28Å; L500-P504 VanDerWaalsContact O-CG 3.26Å; L500-P504 WeakPolarHBondContact O-CG 3.49Å; L500-M554 HydrophobicContact CD1-CE 3.63Å; L500-M554 HydrophobicContact CD1-SD 4.11Å; L500-M554 HydrophobicContact CG-CE 3.98Å; L500-A557 HydrophobicContact CD1-CB 3.98Å; L500-E558 HydrophobicContact CD2-CG 4.39Å; L500-T561 HydrophobicContact CD2-CG2 3.93Å
501	T	90.7	Very high	87.2	Confident	32 Å²	32	20.1 Å²	20.1	20%	0.196	11%	0.11	C	C	.	.	H	α-helix	trans	-102.9	-44.2	177.4	-53	0	0	0	0	112.4	I460 S497 F498 M499 P504 A505	I460-T501 HydrophobicContact CG2-CG2 4.21Å; S497-T501 PolarHBondContact O-OG1 3.01Å; F498-T501 CarbonylContact O-C 3.55Å; F498-T501 WeakPolarHBondContact O-CA 3.45Å; F498-T501 WeakPolarHBondContact O-CB 3.28Å; F498-T501 PolarHBondContact O-N 2.74Å; M499-T501 PolarHBondContact O-N 3.19Å; M499-T501 VanDerWaalsContact O-N 3.14Å; T501-P504 WeakPolarHBondContact O-CD 3.33Å; T501-A505 VanDerWaalsContact O-CB 3.23Å; T501-A505 WeakPolarHBondContact O-CB 3.38Å; T501-A505 PolarHBondContact O-N 3.26Å
502	I	89.4	Confident	87.3	Confident	32 Å²	32	23.1 Å²	23.1	16%	0.164	13%	0.126	C	C	.	.	H	α-helix	trans	-68.7	-49.5	-171	-64.8	154.5	0	0	0	111.9	I349 F352 M356 F498 M499 A505 A506	I349-I502 HydrophobicContact CG2-CG2 3.93Å; F352-I502 HydrophobicContact CD1-CD1 3.9Å; F352-I502 HydrophobicContact CD1-CG1 4.44Å; F352-I502 HydrophobicContact CD1-CG2 3.86Å; F352-I502 HydrophobicContact CE1-CB 4.44Å; F352-I502 HydrophobicContact CE1-CD1 3.31Å; F352-I502 HydrophobicContact CE1-CG1 3.73Å; F352-I502 HydrophobicContact CE1-CG2 3.85Å; F352-I502 HydrophobicContact CZ-CD1 4.32Å; M356-I502 HydrophobicContact CE-CD1 4.3Å; M356-I502 HydrophobicContact SD-CD1 4.36Å; F498-I502 HydrophobicContact CB-CD1 3.84Å; F498-I502 WeakPolarHBondContact O-CD1 3.28Å; F498-I502 WeakPolarHBondContact O-CG1 3.31Å; F498-I502 PolarHBondContact O-N 3.11Å; M499-I502 PolarHBondContact O-N 2.9Å; I502-A505 WeakPolarHBondContact O-CB 3.47Å; I502-A505 PolarHBondContact O-N 3.2Å; I502-A506 PolarHBondContact O-N 3.48Å
503	F	88.6	Confident	87.3	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-64.3	-45	-178.8	-79.3	-86.3	0	0	0	112.3	I349 F350 M499 A505 A506 Q507 I527 R531	I349-F503 HydrophobicContact CB-CD1 4.41Å; I349-F503 HydrophobicContact CB-CE1 3.99Å; I349-F503 HydrophobicContact CB-CZ 4.34Å; I349-F503 HydrophobicContact CG2-CD1 3.58Å; I349-F503 HydrophobicContact CG2-CD2 4.04Å; I349-F503 HydrophobicContact CG2-CE1 3.42Å; I349-F503 VanDerWaalsContact CG2-CE1 3.42Å; I349-F503 HydrophobicContact CG2-CE2 3.88Å; I349-F503 HydrophobicContact CG2-CG 3.95Å; I349-F503 HydrophobicContact CG2-CZ 3.59Å; F350-F503 HydrophobicContact CD1-CE2 4.44Å; F350-F503 AromaticContact CD1-CZ 3.79Å; F350-F503 HydrophobicContact CD1-CZ 3.79Å; F350-F503 HydrophobicContact CD2-CE1 4.35Å; F350-F503 AromaticContact CD2-CZ 3.99Å; F350-F503 HydrophobicContact CD2-CZ 3.99Å; F350-F503 HydrophobicContact CE1-CE2 4.23Å; F350-F503 AromaticContact CE1-CZ 3.6Å; F350-F503 HydrophobicContact CE1-CZ 3.6Å; F350-F503 HydrophobicContact CE2-CE1 4.05Å; F350-F503 AromaticContact CE2-CZ 3.81Å; F350-F503 HydrophobicContact CE2-CZ 3.81Å; F350-F503 AromaticContact CG-CZ 3.98Å; F350-F503 HydrophobicContact CG-CZ 3.98Å; F350-F503 HydrophobicContact CZ-CE1 4.17Å; F350-F503 AromaticContact CZ-CZ 3.61Å; F350-F503 HydrophobicContact CZ-CZ 3.61Å; M499-F503 HydrophobicContact CB-CD2 4.45Å; M499-F503 HydrophobicContact CE-CD2 4.49Å; M499-F503 HydrophobicContact CE-CE2 3.53Å; M499-F503 HydrophobicContact CE-CZ 4.27Å; M499-F503 PolarHBondContact O-N 3.46Å; M499-F503 HydrophobicContact SD-CD2 3.85Å; M499-F503 HydrophobicContact SD-CE2 3.39Å; M499-F503 WeakPolarHBondContact SD-CE2 3.38Å; F503-A505 VanDerWaalsContact C-N 3.31Å; F503-A505 PolarHBondContact O-N 2.92Å; F503-A506 WeakPolarHBondContact O-CB 3.4Å; F503-A506 PolarHBondContact O-N 2.87Å; F503-Q507 WeakPolarHBondContact O-CG 3.27Å; F503-Q507 PolarHBondContact O-N 3.48Å; F503-I527 HydrophobicContact CB-CG2 4.02Å; F503-I527 HydrophobicContact CD1-CB 4.47Å; F503-I527 HydrophobicContact CD1-CG1 4.45Å; F503-I527 HydrophobicContact CD1-CG2 3.49Å; F503-I527 VanDerWaalsContact CD1-CG2 3.49Å; F503-I527 HydrophobicContact CE1-CG2 4.36Å; F503-I527 HydrophobicContact CG-CG2 4.22Å; F503-R531 HydrophobicContact CB-CG 4.01Å; F503-R531 HydrophobicContact CD1-CG 4.04Å; F503-R531 VanDerWaalsContact CD2-CD 3.42Å; F503-R531 HydrophobicContact CD2-CG 4.22Å; F503-R531 HydrophobicContact CE1-CG 4.42Å; F503-R531 HydrophobicContact CG-CG 3.86Å
504	P	90.6	Very high	87.3	Confident	1 Å²	1	23.2 Å²	23.2	1%	0.006	13%	0.13	C	C	.	.	H	α-helix	trans	-66.1	-33.1	175.1	-25	39.3	0	0	0	112.8	A456 Q459 I460 L500 T501 Q507 L508	A456-P504 HydrophobicContact CB-CB 4.41Å; A456-P504 WeakPolarHBondContact O-CB 3.44Å; Q459-P504 HydrophobicContact CB-CB 3.71Å; Q459-P504 HydrophobicContact CB-CG 3.43Å; Q459-P504 VanDerWaalsContact CB-CG 3.43Å; Q459-P504 HydrophobicContact CG-CG 4.25Å; I460-P504 HydrophobicContact CG1-CB 4.05Å; L500-P504 WeakPolarHBondContact O-CD 3.28Å; L500-P504 VanDerWaalsContact O-CG 3.26Å; L500-P504 WeakPolarHBondContact O-CG 3.49Å; T501-P504 WeakPolarHBondContact O-CD 3.33Å; P504-Q507 PolarHBondContact O-N 2.89Å; P504-L508 VanDerWaalsContact O-CB 3.3Å; P504-L508 WeakPolarHBondContact O-CB 3.25Å; P504-L508 PolarHBondContact O-N 3.02Å
505	A	91.3	Very high	86.8	Confident	31 Å²	31	24.5 Å²	24.5	26%	0.256	14%	0.135	S	C	.	.	H	α-helix	trans	-62.1	-42.7	170.9	0	0	0	0	0	111.9	I460 T501 I502 F503 L508 I509	I460-A505 HydrophobicContact CD1-CB 4.27Å; T501-A505 VanDerWaalsContact O-CB 3.23Å; T501-A505 WeakPolarHBondContact O-CB 3.38Å; T501-A505 PolarHBondContact O-N 3.26Å; I502-A505 WeakPolarHBondContact O-CB 3.47Å; I502-A505 PolarHBondContact O-N 3.2Å; F503-A505 VanDerWaalsContact C-N 3.31Å; F503-A505 PolarHBondContact O-N 2.92Å; A505-L508 WeakPolarHBondContact O-CB 3.47Å; A505-L508 PolarHBondContact O-N 3.15Å; A505-I509 VanDerWaalsContact O-CG1 3.28Å; A505-I509 WeakPolarHBondContact O-CG1 3.48Å; A505-I509 PolarHBondContact O-N 3.38Å
506	A	88.6	Confident	86.2	Confident	19 Å²	19	26.9 Å²	26.9	16%	0.157	15%	0.147	C	C	.	.	H	α-helix	trans	-62.2	-43.9	173.7	0	0	0	0	0	111.8	I349 I502 F503 L508 I509 L510 I527	I349-A506 HydrophobicContact CD1-CB 3.69Å; I502-A506 PolarHBondContact O-N 3.48Å; F503-A506 WeakPolarHBondContact O-CB 3.4Å; F503-A506 PolarHBondContact O-N 2.87Å; A506-L508 VanDerWaalsContact C-N 3.32Å; A506-L508 PolarHBondContact O-N 3.49Å; A506-I509 PolarHBondContact O-N 3.47Å; A506-L510 WeakPolarHBondContact O-CB 3.09Å; A506-L510 VanDerWaalsContact O-CG 3.29Å; A506-L510 WeakPolarHBondContact O-CG 3.37Å; A506-L510 PolarHBondContact O-N 3.05Å; A506-I527 HydrophobicContact CB-CD1 4.21Å
507	Q	90.8	Very high	85.9	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-60.9	-40.6	174.6	-68.4	173.8	-51.3	0	0	111.7	F503 P504 L510 S511 I524 I527	F503-Q507 WeakPolarHBondContact O-CG 3.27Å; F503-Q507 PolarHBondContact O-N 3.48Å; P504-Q507 PolarHBondContact O-N 2.89Å; Q507-L510 CarbonylContact O-C 3.55Å; Q507-L510 PolarHBondContact O-N 2.97Å; Q507-S511 WeakPolarHBondContact O-CB 3.28Å; Q507-S511 PolarHBondContact O-N 3.11Å; Q507-I524 HydrophobicContact CB-CG2 4.37Å; Q507-I524 HydrophobicContact CG-CG2 4.13Å; Q507-I524 PolarHBondContact NE2-O 3.47Å; Q507-I527 HydrophobicContact CG-CB 4.14Å; Q507-I527 HydrophobicContact CG-CD1 4.18Å; Q507-I527 HydrophobicContact CG-CG2 3.63Å
508	L	91.7	Very high	85.3	Confident	29 Å²	29	27.3 Å²	27.3	15%	0.152	15%	0.15	C	C	.	.	H	α-helix	trans	-64.3	-45.5	177.9	-176.8	66.1	0	0	0	111.6	R453 A456 W457 I460 P504 A505 A506 L510 S511	R453-L508 HydrophobicContact CB-CD1 4.13Å; R453-L508 HydrophobicContact CG-CD1 3.99Å; A456-L508 HydrophobicContact CB-CB 4.16Å; A456-L508 HydrophobicContact CB-CD1 4.47Å; W457-L508 HydrophobicContact CD2-CD2 4.02Å; W457-L508 VanDerWaalsContact CE2-CD2 3.49Å; W457-L508 HydrophobicContact CH2-CD2 4.19Å; W457-L508 HydrophobicContact CZ2-CD2 3.6Å; I460-L508 HydrophobicContact CD1-CD2 4.05Å; P504-L508 VanDerWaalsContact O-CB 3.3Å; P504-L508 WeakPolarHBondContact O-CB 3.25Å; P504-L508 PolarHBondContact O-N 3.02Å; A505-L508 WeakPolarHBondContact O-CB 3.47Å; A505-L508 PolarHBondContact O-N 3.15Å; A506-L508 VanDerWaalsContact C-N 3.32Å; A506-L508 PolarHBondContact O-N 3.49Å; L508-L510 VanDerWaalsContact C-N 3.29Å; L508-L510 PolarHBondContact O-N 3.25Å; L508-S511 WeakPolarHBondContact O-CB 3.23Å; L508-S511 PolarHBondContact O-N 3.23Å; L508-S511 VanDerWaalsContact O-N 3.15Å; L508-S511 PolarHBondContact O-OG 2.83Å
509	I	90.2	Very high	84.8	Confident	121 Å²	121	24.3 Å²	24.3	62%	0.621	14%	0.137	S	C	*	.	H	α-helix	trans	-60.4	-41.4	176	-68.2	164.6	0	0	0	110.6	A505 A506 S511	A505-I509 VanDerWaalsContact O-CG1 3.28Å; A505-I509 WeakPolarHBondContact O-CG1 3.48Å; A505-I509 PolarHBondContact O-N 3.38Å; A506-I509 PolarHBondContact O-N 3.47Å; I509-S511 VanDerWaalsContact C-N 3.34Å
510	L	87.4	Confident	84.6	Confident	6 Å²	6	24.6 Å²	24.6	3%	0.031	14%	0.138	C	C	.	.	H	α-helix	trans	-76	-18	178.1	-67.1	171.7	0	0	0	113.4	C423 A506 Q507 L508 N512 V514 K520 A523 I524 I527	C423-L510 HydrophobicContact CB-CD2 4.38Å; A506-L510 WeakPolarHBondContact O-CB 3.09Å; A506-L510 VanDerWaalsContact O-CG 3.29Å; A506-L510 WeakPolarHBondContact O-CG 3.37Å; A506-L510 PolarHBondContact O-N 3.05Å; Q507-L510 CarbonylContact O-C 3.55Å; Q507-L510 PolarHBondContact O-N 2.97Å; L508-L510 VanDerWaalsContact C-N 3.29Å; L508-L510 PolarHBondContact O-N 3.25Å; L510-N512 PolarHBondContact O-N 2.94Å; L510-V514 WeakPolarHBondContact O-CG2 3.39Å; L510-K520 HydrophobicContact CD2-CG 4.4Å; L510-K520 WeakPolarHBondContact O-CD 3.36Å; L510-A523 HydrophobicContact CD1-CB 3.91Å; L510-I524 HydrophobicContact CB-CD1 3.96Å; L510-I524 HydrophobicContact CB-CG1 3.79Å; L510-I524 HydrophobicContact CD1-CG1 4.42Å; L510-I527 HydrophobicContact CD1-CD1 4.12Å
511	S	88.2	Confident	84.2	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	14%	0.138	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.9	-8.6	-174.5	75.5	0	0	0	0	114.7	H449 R453 Q507 L508 I509 V513 V514	H449-S511 PolarHBondContact ND1-O 2.76Å; R453-S511 WeakPolarHBondContact CG-OG 3.34Å; R453-S511 PolarHBondContact NE-OG 3.5Å; Q507-S511 WeakPolarHBondContact O-CB 3.28Å; Q507-S511 PolarHBondContact O-N 3.11Å; L508-S511 WeakPolarHBondContact O-CB 3.23Å; L508-S511 PolarHBondContact O-N 3.23Å; L508-S511 VanDerWaalsContact O-N 3.15Å; L508-S511 PolarHBondContact O-OG 2.83Å; I509-S511 VanDerWaalsContact C-N 3.34Å; S511-V513 PolarHBondContact O-N 2.95Å; S511-V514 WeakPolarHBondContact O-CG2 3.38Å
512	N	84.8	Confident	83.6	Confident	76 Å²	76	25 Å²	25	41%	0.406	14%	0.139	S	C	.	.	T	Hydrogen-bonded Turn	trans	-73.4	116.9	179	-69.6	-26.7	0	0	0	111.5	R453 L510 V514 K520	R453-N512 PolarHBondContact NH2-OD1 3.34Å; L510-N512 PolarHBondContact O-N 2.94Å; N512-V514 VanDerWaalsContact C-N 3.29Å; N512-V514 PolarHBondContact O-N 3.27Å; N512-K520 WeakPolarHBondContact O-CD 3.33Å; N512-K520 PolarHBondContact O-NZ 3.33Å
513	V	79.5	Confident	83.3	Confident	54 Å²	54	23.5 Å²	23.5	33%	0.327	13%	0.131	S	C	.	.	T	Hydrogen-bonded Turn	trans	60.3	35.5	171.6	-154.9	0	0	0	0	112.9	S511 H515 L516 S517	S511-V513 PolarHBondContact O-N 2.95Å; V513-H515 VanDerWaalsContact C-N 3.3Å; V513-H515 PolarHBondContact O-N 2.79Å; V513-L516 HydrophobicContact CG1-CB 3.87Å; V513-L516 HydrophobicContact CG1-CD1 3.48Å; V513-L516 VanDerWaalsContact CG1-CD1 3.48Å; V513-L516 HydrophobicContact CG1-CG 3.71Å; V513-L516 PolarHBondContact O-N 3.26Å; V513-L516 VanDerWaalsContact O-N 3.07Å; V513-S517 PolarHBondContact O-N 2.97Å
514	V	80.4	Confident	83.2	Confident	2 Å²	2	23.5 Å²	23.5	1%	0.012	13%	0.131	C	C	.	.	G	3₁₀ helix	trans	-52.2	-42.4	-178.4	176.7	0	0	0	0	113.4	H449 L510 S511 N512 L516 S517 K520 A521 I524 L575	H449-V514 PolarHBondContact CE1-N 3.1Å; L510-V514 WeakPolarHBondContact O-CG2 3.39Å; S511-V514 WeakPolarHBondContact O-CG2 3.38Å; N512-V514 VanDerWaalsContact C-N 3.29Å; N512-V514 PolarHBondContact O-N 3.27Å; V514-L516 PolarHBondContact O-N 3.21Å; V514-L516 VanDerWaalsContact O-N 3.17Å; V514-S517 CarbonylContact O-C 3.54Å; V514-S517 VanDerWaalsContact O-C 3.29Å; V514-S517 PolarHBondContact O-N 2.88Å; V514-S517 VanDerWaalsContact O-O 3.1Å; V514-K520 HydrophobicContact CG2-CB 4.41Å; V514-A521 HydrophobicContact CG1-CB 3.56Å; V514-I524 HydrophobicContact CG1-CD1 4.47Å; V514-I524 HydrophobicContact CG2-CD1 3.6Å; V514-L575 HydrophobicContact CB-CD1 4.23Å; V514-L575 HydrophobicContact CG1-CB 4.39Å; V514-L575 HydrophobicContact CG1-CD1 4.29Å
515	H	74.2	Confident	82.8	Confident	45 Å²	45	24.7 Å²	24.7	21%	0.208	14%	0.137	C	C	.	.	G	3₁₀ helix	trans	-59.1	-24.5	178.8	68.1	-64	0	0	0	115.2	I445 H449 V513 L575 S579	I445-H515 HydrophobicContact CG2-CB 4.46Å; H449-H515 AromaticContact CE1-ND1 3.9Å; H449-H515 AromaticContact NE2-ND1 3.25Å; H449-H515 PolarHBondContact NE2-ND1 3.13Å; V513-H515 VanDerWaalsContact C-N 3.3Å; V513-H515 PolarHBondContact O-N 2.79Å; H515-L575 HydrophobicContact CB-CD2 4.27Å; H515-S579 VanDerWaalsContact O-CB 3.24Å; H515-S579 WeakPolarHBondContact O-CB 3.01Å; H515-S579 PolarHBondContact O-OG 1.98Å
516	L	74.1	Confident	82.3	Confident	50 Å²	50	23.8 Å²	23.8	26%	0.262	13%	0.131	S	C	.	.	G	3₁₀ helix	trans	-95.4	-7.6	175.4	-57.4	-178	0	0	0	112.7	R427 I428 V513 V514	R427-L516 CarbonylContact C-O 3.6Å; R427-L516 VanDerWaalsContact CA-O 3.3Å; R427-L516 WeakPolarHBondContact CA-O 3.38Å; I428-L516 PolarHBondContact N-O 3.03Å; V513-L516 HydrophobicContact CG1-CB 3.87Å; V513-L516 HydrophobicContact CG1-CD1 3.48Å; V513-L516 VanDerWaalsContact CG1-CD1 3.48Å; V513-L516 HydrophobicContact CG1-CG 3.71Å; V513-L516 PolarHBondContact O-N 3.26Å; V513-L516 VanDerWaalsContact O-N 3.07Å; V514-L516 PolarHBondContact O-N 3.21Å; V514-L516 VanDerWaalsContact O-N 3.17Å
517	S	76.7	Confident	82.1	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.123	C	C	.	.			trans	-130.1	83.7	-174.5	-77.6	0	0	0	0	109.8	Y426 V513 V514 M519 K520 A521	Y426-S517 WeakPolarHBondContact O-CA 3.37Å; Y426-S517 WeakPolarHBondContact O-CB 3.29Å; Y426-S517 PolarHBondContact O-OG 3.48Å; V513-S517 PolarHBondContact O-N 2.97Å; V514-S517 CarbonylContact O-C 3.54Å; V514-S517 VanDerWaalsContact O-C 3.29Å; V514-S517 PolarHBondContact O-N 2.88Å; V514-S517 VanDerWaalsContact O-O 3.1Å; S517-M519 PolarHBondContact O-N 3.32Å; S517-M519 VanDerWaalsContact O-N 3.07Å; S517-K520 WeakPolarHBondContact O-CB 3.45Å; S517-K520 PolarHBondContact O-N 3.49Å; S517-A521 PolarHBondContact O-N 2.89Å
518	P	72.5	Confident	81.9	Confident	9 Å²	9	22.9 Å²	22.9	6%	0.058	12%	0.123	C	C	.	.	H	α-helix	trans	-56.8	-27.8	-177.4	19.5	-32.2	0	0	0	113.4	F338 I428 A521 L522 F576	F338-P518 HydrophobicContact CE2-CB 3.93Å; F338-P518 HydrophobicContact CE2-CG 3.95Å; F338-P518 HydrophobicContact CZ-CB 3.95Å; F338-P518 HydrophobicContact CZ-CG 4.45Å; I428-P518 HydrophobicContact CD1-CG 3.96Å; I428-P518 HydrophobicContact CG1-CG 3.99Å; P518-A521 WeakPolarHBondContact O-CB 3.38Å; P518-A521 PolarHBondContact O-N 3.32Å; P518-L522 PolarHBondContact O-N 3.04Å; P518-F576 HydrophobicContact CB-CD2 4.12Å; P518-F576 HydrophobicContact CB-CE2 3.64Å
519	M	77.2	Confident	81.3	Confident	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-66.9	-35.2	174	-71.2	-173.2	61.7	0	0	113.8	F338 I341 P342 C423 Y426 S517 A521 L522 A523	F338-M519 HydrophobicContact CB-SD 4.32Å; F338-M519 HydrophobicContact CD2-CB 4.49Å; F338-M519 HydrophobicContact CD2-CG 3.1Å; F338-M519 HydrophobicContact CD2-SD 3.65Å; F338-M519 HydrophobicContact CE2-CB 4.31Å; F338-M519 HydrophobicContact CE2-CG 3.22Å; F338-M519 HydrophobicContact CE2-SD 4.34Å; F338-M519 HydrophobicContact CG-CG 3.89Å; F338-M519 HydrophobicContact CG-SD 4.25Å; F338-M519 HydrophobicContact CZ-CG 4.1Å; F338-M519 WeakPolarHBondContact O-CE 3.23Å; I341-M519 HydrophobicContact CB-CE 3.53Å; I341-M519 HydrophobicContact CD1-CE 3.82Å; I341-M519 HydrophobicContact CG1-CE 4.21Å; I341-M519 HydrophobicContact CG2-CE 3.72Å; P342-M519 HydrophobicContact CG-CE 4.25Å; C423-M519 HydrophobicContact CB-CB 4.26Å; Y426-M519 WeakPolarHBondContact CB-SD 3.47Å; Y426-M519 HydrophobicContact CD1-SD 3.69Å; Y426-M519 HydrophobicContact CD2-CE 3.87Å; Y426-M519 HydrophobicContact CD2-SD 3.03Å; Y426-M519 WeakPolarHBondContact CD2-SD 3.39Å; Y426-M519 HydrophobicContact CE1-SD 4.05Å; Y426-M519 HydrophobicContact CE2-CE 3.92Å; Y426-M519 HydrophobicContact CE2-SD 3.44Å; Y426-M519 WeakPolarHBondContact CE2-SD 3.45Å; Y426-M519 HydrophobicContact CG-CE 4.47Å; Y426-M519 HydrophobicContact CG-CG 4.27Å; Y426-M519 HydrophobicContact CG-SD 3.1Å; S517-M519 PolarHBondContact O-N 3.32Å; S517-M519 VanDerWaalsContact O-N 3.07Å; M519-A521 VanDerWaalsContact C-N 3.34Å; M519-L522 PolarHBondContact O-N 3.28Å; M519-A523 WeakPolarHBondContact O-CB 3.43Å; M519-A523 PolarHBondContact O-N 2.81Å
520	K	83	Confident	80.8	Confident	8 Å²	8	17.9 Å²	17.9	4%	0.035	10%	0.101	C	C	.	.	H	α-helix	trans	-65.3	-42.5	173	-70.7	177.7	165	171.9	0	110.6	C423 S424 L510 N512 V514 S517 L522 A523 I524	C423-K520 HydrophobicContact CB-CG 4Å; S424-K520 WeakPolarHBondContact OG-CE 3.34Å; S424-K520 PolarHBondContact OG-NZ 3.5Å; L510-K520 HydrophobicContact CD2-CG 4.4Å; L510-K520 WeakPolarHBondContact O-CD 3.36Å; N512-K520 WeakPolarHBondContact O-CD 3.33Å; N512-K520 PolarHBondContact O-NZ 3.33Å; V514-K520 HydrophobicContact CG2-CB 4.41Å; S517-K520 WeakPolarHBondContact O-CB 3.45Å; S517-K520 PolarHBondContact O-N 3.49Å; K520-L522 VanDerWaalsContact C-N 3.33Å; K520-L522 PolarHBondContact O-N 2.92Å; K520-A523 PolarHBondContact O-N 3Å; K520-I524 VanDerWaalsContact O-CG1 3.24Å; K520-I524 WeakPolarHBondContact O-CG1 3.26Å; K520-I524 PolarHBondContact O-N 3.45Å
521	A	79.5	Confident	80.7	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-58.9	-47.9	176	0	0	0	0	0	110.4	V514 S517 P518 M519 A523 I524 I525 F576	V514-A521 HydrophobicContact CG1-CB 3.56Å; S517-A521 PolarHBondContact O-N 2.89Å; P518-A521 WeakPolarHBondContact O-CB 3.38Å; P518-A521 PolarHBondContact O-N 3.32Å; M519-A521 VanDerWaalsContact C-N 3.34Å; A521-A523 PolarHBondContact O-N 3.28Å; A521-I524 PolarHBondContact O-N 2.87Å; A521-I525 WeakPolarHBondContact O-CB 3.5Å; A521-I525 VanDerWaalsContact O-CG1 3.25Å; A521-I525 WeakPolarHBondContact O-CG1 3.44Å; A521-I525 PolarHBondContact O-N 3.37Å; A521-F576 HydrophobicContact CB-CB 4.34Å; A521-F576 HydrophobicContact CB-CD2 3.89Å
522	L	78.1	Confident	80.3	Confident	43 Å²	43	18.3 Å²	18.3	23%	0.225	10%	0.104	C	C	.	.	H	α-helix	trans	-61.7	-42.1	177.8	-175.6	61.1	0	0	0	112.4	F338 Y339 P342 P518 M519 K520 G526	F338-L522 HydrophobicContact CD1-CD2 4.01Å; F338-L522 HydrophobicContact CE1-CD2 3.64Å; F338-L522 HydrophobicContact CZ-CD2 4.44Å; Y339-L522 HydrophobicContact CD1-CD2 3.69Å; Y339-L522 HydrophobicContact CE1-CD2 4.15Å; Y339-L522 HydrophobicContact CG-CD2 4.45Å; P342-L522 HydrophobicContact CB-CD2 4.48Å; P342-L522 HydrophobicContact CB-CG 4.33Å; P342-L522 HydrophobicContact CG-CB 4.43Å; P342-L522 HydrophobicContact CG-CD2 4.12Å; P342-L522 HydrophobicContact CG-CG 4.29Å; P518-L522 PolarHBondContact O-N 3.04Å; M519-L522 PolarHBondContact O-N 3.28Å; K520-L522 VanDerWaalsContact C-N 3.33Å; K520-L522 PolarHBondContact O-N 2.92Å; L522-G526 PolarHBondContact O-N 3.41Å
523	A	82.7	Confident	79.9	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-63.7	-44.1	175.9	0	0	0	0	0	112.1	P342 L510 M519 K520 A521 G526 I527	P342-A523 HydrophobicContact CB-CB 3.99Å; P342-A523 HydrophobicContact CG-CB 4.39Å; L510-A523 HydrophobicContact CD1-CB 3.91Å; M519-A523 WeakPolarHBondContact O-CB 3.43Å; M519-A523 PolarHBondContact O-N 2.81Å; K520-A523 PolarHBondContact O-N 3Å; A521-A523 PolarHBondContact O-N 3.28Å; A523-G526 PolarHBondContact O-N 2.66Å; A523-I527 WeakPolarHBondContact O-CB 2.91Å; A523-I527 VanDerWaalsContact O-CG1 3.24Å; A523-I527 WeakPolarHBondContact O-CG1 3.4Å; A523-I527 PolarHBondContact O-N 3Å
524	I	86.3	Confident	79.7	Confident	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-64.9	-44	178.4	-66.2	164.2	0	0	0	111.2	Q507 L510 V514 K520 A521 I527 A528 I568 C572	Q507-I524 HydrophobicContact CB-CG2 4.37Å; Q507-I524 HydrophobicContact CG-CG2 4.13Å; Q507-I524 PolarHBondContact NE2-O 3.47Å; L510-I524 HydrophobicContact CB-CD1 3.96Å; L510-I524 HydrophobicContact CB-CG1 3.79Å; L510-I524 HydrophobicContact CD1-CG1 4.42Å; V514-I524 HydrophobicContact CG1-CD1 4.47Å; V514-I524 HydrophobicContact CG2-CD1 3.6Å; K520-I524 VanDerWaalsContact O-CG1 3.24Å; K520-I524 WeakPolarHBondContact O-CG1 3.26Å; K520-I524 PolarHBondContact O-N 3.45Å; A521-I524 PolarHBondContact O-N 2.87Å; I524-I527 PolarHBondContact O-N 3Å; I524-A528 WeakPolarHBondContact O-CB 3.43Å; I524-A528 PolarHBondContact O-N 2.93Å; I524-I568 HydrophobicContact CG2-CG2 3.4Å; I524-C572 WeakPolarHBondContact CG2-SG 3.4Å
525	I	82.6	Confident	79.7	Confident	25 Å²	25	13 Å²	13	13%	0.128	7%	0.074	C	C	.	.	H	α-helix	trans	-63.4	-46.6	176.5	-68.4	167.4	0	0	0	110	A521 I527 A528 C529 C572	A521-I525 WeakPolarHBondContact O-CB 3.5Å; A521-I525 VanDerWaalsContact O-CG1 3.25Å; A521-I525 WeakPolarHBondContact O-CG1 3.44Å; A521-I525 PolarHBondContact O-N 3.37Å; I525-I527 VanDerWaalsContact C-N 3.35Å; I525-I527 PolarHBondContact O-N 3.26Å; I525-A528 WeakPolarHBondContact O-CB 3.44Å; I525-A528 PolarHBondContact O-N 3.3Å; I525-A528 VanDerWaalsContact O-N 3.09Å; I525-C529 PolarHBondContact O-N 2.69Å; I525-C529 PolarHBondContact O-SG 3.29Å; I525-C529 VanDerWaalsContact O-SG 3.34Å; I525-C572 HydrophobicContact CD1-CB 4.17Å; I525-C572 HydrophobicContact CG1-CB 3.82Å
526	G	79.1	Confident	79.5	Confident	12 Å²	12	12.3 Å²	12.3	12%	0.124	7%	0.071	C	C	.	.	H	α-helix	trans	-62.4	-39.8	178.9	0	0	0	0	0	112.8	I346 L522 A523 S530	I346-G526 VanDerWaalsContact CD1-C 3.49Å; L522-G526 PolarHBondContact O-N 3.41Å; A523-G526 PolarHBondContact O-N 2.66Å; G526-S530 WeakPolarHBondContact O-CB 3.46Å; G526-S530 PolarHBondContact O-N 2.89Å; G526-S530 PolarHBondContact O-OG 2.92Å
527	I	86.4	Confident	79.1	Confident	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-58.8	-48.9	170.3	-72.4	166.5	0	0	0	110.2	I346 I349 F503 A506 Q507 L510 A523 I524 I525 S530 R531	I346-I527 HydrophobicContact CG1-CG1 3.83Å; I349-I527 HydrophobicContact CD1-CD1 3.91Å; I349-I527 HydrophobicContact CD1-CG1 4.29Å; F503-I527 HydrophobicContact CB-CG2 4.02Å; F503-I527 HydrophobicContact CD1-CB 4.47Å; F503-I527 HydrophobicContact CD1-CG1 4.45Å; F503-I527 HydrophobicContact CD1-CG2 3.49Å; F503-I527 VanDerWaalsContact CD1-CG2 3.49Å; F503-I527 HydrophobicContact CE1-CG2 4.36Å; F503-I527 HydrophobicContact CG-CG2 4.22Å; A506-I527 HydrophobicContact CB-CD1 4.21Å; Q507-I527 HydrophobicContact CG-CB 4.14Å; Q507-I527 HydrophobicContact CG-CD1 4.18Å; Q507-I527 HydrophobicContact CG-CG2 3.63Å; L510-I527 HydrophobicContact CD1-CD1 4.12Å; A523-I527 WeakPolarHBondContact O-CB 2.91Å; A523-I527 VanDerWaalsContact O-CG1 3.24Å; A523-I527 WeakPolarHBondContact O-CG1 3.4Å; A523-I527 PolarHBondContact O-N 3Å; I524-I527 PolarHBondContact O-N 3Å; I525-I527 VanDerWaalsContact C-N 3.35Å; I525-I527 PolarHBondContact O-N 3.26Å; I527-S530 PolarHBondContact O-N 3.37Å; I527-R531 HydrophobicContact CG2-CG 4.48Å; I527-R531 WeakPolarHBondContact O-CG 3.33Å; I527-R531 PolarHBondContact O-N 3.4Å
528	A	85.7	Confident	78.8	Confident	0 Å²	0	12.1 Å²	12.1	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-63.7	-47	-176.8	0	0	0	0	0	112.6	I524 I525 S530 R531 V532 Q565 M569	I524-A528 WeakPolarHBondContact O-CB 3.43Å; I524-A528 PolarHBondContact O-N 2.93Å; I525-A528 WeakPolarHBondContact O-CB 3.44Å; I525-A528 PolarHBondContact O-N 3.3Å; I525-A528 VanDerWaalsContact O-N 3.09Å; A528-S530 PolarHBondContact O-N 3.47Å; A528-R531 PolarHBondContact O-N 3.03Å; A528-V532 WeakPolarHBondContact O-CG2 3.26Å; A528-V532 PolarHBondContact O-N 3.47Å; A528-Q565 HydrophobicContact CB-CB 4.32Å; A528-M569 HydrophobicContact CB-CG 3.42Å; A528-M569 VanDerWaalsContact CB-CG 3.42Å; A528-M569 HydrophobicContact CB-SD 4.15Å
529	C	78.9	Confident	78.6	Confident	27 Å²	27	11.8 Å²	11.8	18%	0.182	7%	0.067	C	C	.	.	H	α-helix	trans	-58.9	-47.5	175.6	-65.6	0	0	0	0	111.3	I525 R531 V532 I533 M569	I525-C529 PolarHBondContact O-N 2.69Å; I525-C529 PolarHBondContact O-SG 3.29Å; I525-C529 VanDerWaalsContact O-SG 3.34Å; C529-R531 VanDerWaalsContact C-N 3.27Å; C529-R531 PolarHBondContact O-N 3.01Å; C529-V532 PolarHBondContact O-N 2.71Å; C529-I533 WeakPolarHBondContact O-CG1 3.39Å; C529-I533 PolarHBondContact O-N 2.95Å; C529-M569 HydrophobicContact CB-SD 4.49Å; C529-M569 PolarHBondContact SG-SD 3.18Å
530	S	80.4	Confident	77.7	Confident	18 Å²	18	13.4 Å²	13.4	13%	0.126	8%	0.076	C	C	.	.	H	α-helix	trans	-61.9	-37.3	-179.8	-53.5	0	0	0	0	111.7	G526 I527 A528 D534	G526-S530 WeakPolarHBondContact O-CB 3.46Å; G526-S530 PolarHBondContact O-N 2.89Å; G526-S530 PolarHBondContact O-OG 2.92Å; I527-S530 PolarHBondContact O-N 3.37Å; A528-S530 PolarHBondContact O-N 3.47Å; S530-D534 VanDerWaalsContact O-CB 3.31Å; S530-D534 WeakPolarHBondContact O-CB 3.03Å; S530-D534 PolarHBondContact O-N 3.29Å
531	R	84	Confident	76.4	Confident	2 Å²	2	17.8 Å²	17.8	1%	0.008	9%	0.093	C	C	.	.	H	α-helix	trans	-69	-39.3	174.6	-74.9	-54.4	-63.1	163.2	5.3	113.6	F503 I527 A528 C529 I533 D534 I535 Q565	F503-R531 HydrophobicContact CB-CG 4.01Å; F503-R531 HydrophobicContact CD1-CG 4.04Å; F503-R531 VanDerWaalsContact CD2-CD 3.42Å; F503-R531 HydrophobicContact CD2-CG 4.22Å; F503-R531 HydrophobicContact CE1-CG 4.42Å; F503-R531 HydrophobicContact CG-CG 3.86Å; I527-R531 HydrophobicContact CG2-CG 4.48Å; I527-R531 WeakPolarHBondContact O-CG 3.33Å; I527-R531 PolarHBondContact O-N 3.4Å; A528-R531 PolarHBondContact O-N 3.03Å; C529-R531 VanDerWaalsContact C-N 3.27Å; C529-R531 PolarHBondContact O-N 3.01Å; R531-I533 VanDerWaalsContact C-N 3.33Å; R531-D534 IonicContact CZ-OD2 3.29Å; R531-D534 IonicContact NH1-OD2 3.6Å; R531-D534 PolarHBondContact NH1-OD2 3.31Å; R531-D534 IonicContact NH2-OD2 2.74Å; R531-D534 PolarHBondContact O-N 2.85Å; R531-I535 WeakPolarHBondContact O-CB 3.35Å; R531-I535 WeakPolarHBondContact O-CD1 3.47Å; R531-I535 WeakPolarHBondContact O-CG1 3.49Å; R531-I535 PolarHBondContact O-N 3.07Å; R531-Q565 HydrophobicContact CB-CG 4.07Å
532	V	81.4	Confident	75.5	Confident	14 Å²	14	19 Å²	19	9%	0.085	10%	0.097	C	C	.	.	H	α-helix	trans	-59.8	-48.4	175.6	167.1	0	0	0	0	110	L77 A528 C529 I535 L536 L562 Q565 M569	L77-V532 HydrophobicContact CD1-CG1 4.35Å; A528-V532 WeakPolarHBondContact O-CG2 3.26Å; A528-V532 PolarHBondContact O-N 3.47Å; C529-V532 PolarHBondContact O-N 2.71Å; V532-I535 PolarHBondContact O-N 2.61Å; V532-L536 HydrophobicContact CG1-CD1 3.89Å; V532-L536 HydrophobicContact CG1-CG 4.5Å; V532-L536 WeakPolarHBondContact O-CB 3.31Å; V532-L536 VanDerWaalsContact O-CG 3.24Å; V532-L536 WeakPolarHBondContact O-CG 3.29Å; V532-L536 PolarHBondContact O-N 2.81Å; V532-L562 HydrophobicContact CB-CD2 4.23Å; V532-L562 HydrophobicContact CG1-CD2 4.07Å; V532-L562 HydrophobicContact CG2-CD2 4.21Å; V532-Q565 HydrophobicContact CG2-CB 3.81Å; V532-M569 HydrophobicContact CG2-CE 4.26Å
533	I	74.5	Confident	74.2	Confident	13 Å²	13	20.6 Å²	20.6	7%	0.067	11%	0.106	C	C	.	.	H	α-helix	trans	-62.5	-47.9	178.8	-60.5	160.6	0	0	0	111	W174 I206 Y209 C529 R531 I535 L536 I537	W174-I533 HydrophobicContact CH2-CG2 3.85Å; W174-I533 HydrophobicContact CZ2-CG2 4.17Å; I206-I533 HydrophobicContact CB-CD1 4.01Å; I206-I533 HydrophobicContact CG1-CD1 4.02Å; I206-I533 HydrophobicContact CG2-CD1 3.64Å; I206-I533 HydrophobicContact CG2-CG1 4.28Å; Y209-I533 HydrophobicContact CD1-CB 4.42Å; Y209-I533 HydrophobicContact CD1-CG2 3.52Å; Y209-I533 HydrophobicContact CE1-CG2 4.12Å; Y209-I533 HydrophobicContact CG-CG2 4.37Å; C529-I533 WeakPolarHBondContact O-CG1 3.39Å; C529-I533 PolarHBondContact O-N 2.95Å; R531-I533 VanDerWaalsContact C-N 3.33Å; I533-I535 VanDerWaalsContact C-N 3.34Å; I533-I535 PolarHBondContact O-N 2.87Å; I533-L536 PolarHBondContact O-N 3.24Å; I533-I537 HydrophobicContact CG2-CD1 3.66Å; I533-I537 HydrophobicContact CG2-CG1 4.39Å; I533-I537 WeakPolarHBondContact O-CB 3.48Å; I533-I537 WeakPolarHBondContact O-CG1 3.07Å; I533-I537 PolarHBondContact O-N 3.37Å
534	D	76.8	Confident	72.6	Confident	7 Å²	7	20.9 Å²	20.9	4%	0.037	11%	0.108	C	C	.	.	H	α-helix	trans	-61.1	-42.2	-179	-177.5	48.4	0	0	0	112.1	Y209 S530 R531 I537 Q538	Y209-D534 HydrophobicContact CE1-CB 4.36Å; Y209-D534 PolarHBondContact OH-OD1 2.92Å; S530-D534 VanDerWaalsContact O-CB 3.31Å; S530-D534 WeakPolarHBondContact O-CB 3.03Å; S530-D534 PolarHBondContact O-N 3.29Å; R531-D534 IonicContact CZ-OD2 3.29Å; R531-D534 IonicContact NH1-OD2 3.6Å; R531-D534 PolarHBondContact NH1-OD2 3.31Å; R531-D534 IonicContact NH2-OD2 2.74Å; R531-D534 PolarHBondContact O-N 2.85Å; D534-I537 PolarHBondContact O-N 3.2Å; D534-Q538 WeakPolarHBondContact O-CB 3.26Å; D534-Q538 VanDerWaalsContact O-CG 3.22Å; D534-Q538 WeakPolarHBondContact O-CG 3.41Å; D534-Q538 PolarHBondContact O-N 2.98Å; D534-Q538 PolarHBondContact OD1-NE2 3.39Å; D534-Q538 PolarHBondContact OD2-NE2 3.39Å
535	I	79.1	Confident	70.4	Confident	0 Å²	0	21.4 Å²	21.4	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-64.7	-46.4	176.2	-70	166.6	0	0	0	110.9	R531 V532 I533 I537 Q538 I539 E558 T561 L562	R531-I535 WeakPolarHBondContact O-CB 3.35Å; R531-I535 WeakPolarHBondContact O-CD1 3.47Å; R531-I535 WeakPolarHBondContact O-CG1 3.49Å; R531-I535 PolarHBondContact O-N 3.07Å; V532-I535 PolarHBondContact O-N 2.61Å; I533-I535 VanDerWaalsContact C-N 3.34Å; I533-I535 PolarHBondContact O-N 2.87Å; I535-I537 VanDerWaalsContact C-N 3.28Å; I535-I537 PolarHBondContact O-N 3.47Å; I535-Q538 PolarHBondContact O-N 3.45Å; I535-I539 HydrophobicContact CG2-CD1 3.54Å; I535-I539 HydrophobicContact CG2-CG1 4.16Å; I535-I539 VanDerWaalsContact O-CG1 3.28Å; I535-I539 WeakPolarHBondContact O-CG1 3.39Å; I535-I539 PolarHBondContact O-N 3.27Å; I535-E558 HydrophobicContact CG1-CG 4.26Å; I535-E558 HydrophobicContact CG2-CB 3.7Å; I535-E558 HydrophobicContact CG2-CG 4.17Å; I535-T561 HydrophobicContact CD1-CG2 3.69Å; I535-L562 HydrophobicContact CB-CD2 3.75Å; I535-L562 HydrophobicContact CB-CG 4.28Å; I535-L562 HydrophobicContact CD1-CD2 4.16Å; I535-L562 HydrophobicContact CD1-CG 4.44Å; I535-L562 HydrophobicContact CG2-CD1 3.92Å; I535-L562 HydrophobicContact CG2-CD2 3.65Å; I535-L562 HydrophobicContact CG2-CG 3.65Å
536	L	70.5	Confident	68.9	Low	30 Å²	30	29.4 Å²	29.4	16%	0.157	14%	0.142	C	C	.	.	H	α-helix	trans	-58.9	-43.3	179.5	-72.5	171.5	0	0	0	111.4	V532 I533 D540 L562	V532-L536 HydrophobicContact CG1-CD1 3.89Å; V532-L536 HydrophobicContact CG1-CG 4.5Å; V532-L536 WeakPolarHBondContact O-CB 3.31Å; V532-L536 VanDerWaalsContact O-CG 3.24Å; V532-L536 WeakPolarHBondContact O-CG 3.29Å; V532-L536 PolarHBondContact O-N 2.81Å; I533-L536 PolarHBondContact O-N 3.24Å; L536-D540 PolarHBondContact O-N 2.92Å; L536-L562 HydrophobicContact CD2-CD1 4.09Å; L536-L562 HydrophobicContact CG-CD2 4.33Å
537	I	66.2	Low	67.9	Low	21 Å²	21	31.3 Å²	31.3	11%	0.108	15%	0.149	C	C	.	.	H	α-helix	trans	-63.8	-48.2	175.9	-75	174	0	0	0	110.8	W174 Y209 I533 D534 I535 I539 D540 Y541	W174-I537 HydrophobicContact CZ2-CD1 4.22Å; Y209-I537 HydrophobicContact CD1-CD1 3.89Å; Y209-I537 HydrophobicContact CE1-CD1 3.72Å; I533-I537 HydrophobicContact CG2-CD1 3.66Å; I533-I537 HydrophobicContact CG2-CG1 4.39Å; I533-I537 WeakPolarHBondContact O-CB 3.48Å; I533-I537 WeakPolarHBondContact O-CG1 3.07Å; I533-I537 PolarHBondContact O-N 3.37Å; D534-I537 PolarHBondContact O-N 3.2Å; I535-I537 VanDerWaalsContact C-N 3.28Å; I535-I537 PolarHBondContact O-N 3.47Å; I537-I539 PolarHBondContact O-N 3.47Å; I537-D540 WeakPolarHBondContact O-CB 3.41Å; I537-D540 PolarHBondContact O-N 3.27Å; I537-Y541 HydrophobicContact CG2-CD2 3.66Å; I537-Y541 HydrophobicContact CG2-CE2 3.6Å; I537-Y541 WeakPolarHBondContact O-CD2 3.24Å; I537-Y541 PolarHBondContact O-N 3.4Å; I537-Y541 VanDerWaalsContact O-N 3.14Å
538	Q	69.4	Low	66.9	Low	25 Å²	25	32.4 Å²	32.4	12%	0.117	16%	0.161	C	C	.	.	H	α-helix	trans	-65.2	-37.8	-176.9	-76.6	179.1	24	0	0	113.7	D534 I535 D540 Y541 R542 E558	D534-Q538 WeakPolarHBondContact O-CB 3.26Å; D534-Q538 VanDerWaalsContact O-CG 3.22Å; D534-Q538 WeakPolarHBondContact O-CG 3.41Å; D534-Q538 PolarHBondContact O-N 2.98Å; D534-Q538 PolarHBondContact OD1-NE2 3.39Å; D534-Q538 PolarHBondContact OD2-NE2 3.39Å; I535-Q538 PolarHBondContact O-N 3.45Å; Q538-D540 VanDerWaalsContact C-N 3.25Å; Q538-D540 PolarHBondContact O-N 3.49Å; Q538-Y541 PolarHBondContact O-N 3.07Å; Q538-R542 WeakPolarHBondContact O-CG 3.18Å; Q538-R542 PolarHBondContact O-N 2.86Å; Q538-E558 PolarHBondContact OE1-OE1 2.89Å
539	I	68.6	Low	66.3	Low	3 Å²	3	36.5 Å²	36.5	2%	0.015	19%	0.185	C	C	.	.	H	α-helix	trans	-62.8	-38.6	176.8	-68.7	171.1	0	0	0	110	W70 I535 I537 R542 E558 I559 L562	W70-I539 HydrophobicContact CB-CG2 3.72Å; W70-I539 HydrophobicContact CD2-CG2 3.31Å; W70-I539 HydrophobicContact CE3-CG2 3.69Å; W70-I539 HydrophobicContact CG-CG2 3.35Å; W70-I539 HydrophobicContact CZ2-CG2 4.44Å; W70-I539 HydrophobicContact CZ3-CG2 4.4Å; I535-I539 HydrophobicContact CG2-CD1 3.54Å; I535-I539 HydrophobicContact CG2-CG1 4.16Å; I535-I539 VanDerWaalsContact O-CG1 3.28Å; I535-I539 WeakPolarHBondContact O-CG1 3.39Å; I535-I539 PolarHBondContact O-N 3.27Å; I537-I539 PolarHBondContact O-N 3.47Å; I539-R542 PolarHBondContact O-N 2.84Å; I539-E558 HydrophobicContact CD1-CB 4.27Å; I539-I559 HydrophobicContact CD1-CG1 4.26Å; I539-L562 HydrophobicContact CD1-CD1 4.48Å
540	D	57.8	Low	66.2	Low	34 Å²	34	35.2 Å²	35.2	18%	0.182	18%	0.176	C	C	.	.	H	α-helix	trans	-69.3	-35.7	179.9	-158.3	38.4	0	0	0	113	L536 I537 Q538 R542	L536-D540 PolarHBondContact O-N 2.92Å; I537-D540 WeakPolarHBondContact O-CB 3.41Å; I537-D540 PolarHBondContact O-N 3.27Å; Q538-D540 VanDerWaalsContact C-N 3.25Å; Q538-D540 PolarHBondContact O-N 3.49Å; D540-R542 VanDerWaalsContact C-N 3.34Å; D540-R542 PolarHBondContact O-N 3.22Å
541	Y	55.9	Low	66	Low	100 Å²	100	35.4 Å²	35.4	39%	0.392	18%	0.175	S	C	.	.	H	α-helix	trans	-76.1	-16	179	-81.6	-70	0	0	0	114.6	I537 Q538 N543	I537-Y541 HydrophobicContact CG2-CD2 3.66Å; I537-Y541 HydrophobicContact CG2-CE2 3.6Å; I537-Y541 WeakPolarHBondContact O-CD2 3.24Å; I537-Y541 PolarHBondContact O-N 3.4Å; I537-Y541 VanDerWaalsContact O-N 3.14Å; Q538-Y541 PolarHBondContact O-N 3.07Å; Y541-N543 PolarHBondContact O-N 2.78Å
542	R	61.4	Low	65.7	Low	24 Å²	24	37.6 Å²	37.6	9%	0.091	19%	0.193	C	C	.	.	S	Bend	trans	-75.3	125.9	-178.5	-75.9	173	-167.1	169.4	11.3	110.1	Q538 I539 D540 L544 W551 T555 E558	Q538-R542 WeakPolarHBondContact O-CG 3.18Å; Q538-R542 PolarHBondContact O-N 2.86Å; I539-R542 PolarHBondContact O-N 2.84Å; D540-R542 VanDerWaalsContact C-N 3.34Å; D540-R542 PolarHBondContact O-N 3.22Å; R542-L544 VanDerWaalsContact C-N 3.31Å; R542-L544 HydrophobicContact CB-CD2 3.83Å; R542-L544 HydrophobicContact CB-CG 4.23Å; R542-L544 PolarHBondContact O-N 3.41Å; R542-W551 HydrophobicContact CG-CZ3 4.46Å; R542-T555 PolarHBondContact NH1-OG1 2.8Å; R542-E558 IonicContact CZ-OE1 2.86Å; R542-E558 IonicContact CZ-OE2 3.68Å; R542-E558 IonicContact NH1-OE1 3.9Å; R542-E558 IonicContact NH1-OE2 3.54Å; R542-E558 PolarHBondContact NH1-OE2 2.96Å; R542-E558 IonicContact NH2-OE1 3.12Å; R542-E558 PolarHBondContact NH2-OE1 3.48Å; R542-E558 IonicContact NH2-OE2 2.71Å; R542-E558 PolarHBondContact NH2-OE2 2.82Å
543	N	50.4	Low	65.7	Low	78 Å²	78	38.2 Å²	38.2	42%	0.417	20%	0.2	S	C	.	.			trans	-75.1	92.5	165.1	-168.6	-5.5	0	0	0	108.2	V57 Y541 A545	V57-N543 PolarHBondContact O-OD1 2.99Å; Y541-N543 PolarHBondContact O-N 2.78Å; N543-A545 PolarHBondContact O-N 2.93Å; N543-A545 WeakPolarHBondContact OD1-CB 3.49Å; N543-A545 PolarHBondContact OD1-N 3.5Å
544	L	50.1	Low	66.1	Low	5 Å²	5	37.6 Å²	37.6	3%	0.026	20%	0.196	C	C	.	.	G	3₁₀ helix	trans	-71.8	-6.5	-173.4	-58	161.5	0	0	0	112.8	T52 V57 W70 R542 Y546 L547	T52-L544 HydrophobicContact CG2-CB 3.44Å; T52-L544 VanDerWaalsContact CG2-CB 3.44Å; T52-L544 HydrophobicContact CG2-CD1 3.88Å; T52-L544 HydrophobicContact CG2-CD2 4.46Å; T52-L544 HydrophobicContact CG2-CG 4.09Å; T52-L544 WeakPolarHBondContact OG1-CD1 3.33Å; V57-L544 HydrophobicContact CG2-CB 4.28Å; W70-L544 HydrophobicContact CZ2-CD1 3.65Å; R542-L544 VanDerWaalsContact C-N 3.31Å; R542-L544 HydrophobicContact CB-CD2 3.83Å; R542-L544 HydrophobicContact CB-CG 4.23Å; R542-L544 PolarHBondContact O-N 3.41Å; L544-Y546 PolarHBondContact O-N 3.41Å; L544-L547 HydrophobicContact CB-CD1 3.64Å; L544-L547 HydrophobicContact CB-CG 4.16Å; L544-L547 HydrophobicContact CD2-CD1 3.66Å; L544-L547 HydrophobicContact CD2-CD2 3.94Å; L544-L547 HydrophobicContact CD2-CG 4.19Å; L544-L547 HydrophobicContact CG-CD1 4.22Å; L544-L547 VanDerWaalsContact O-CD1 3.24Å; L544-L547 WeakPolarHBondContact O-CD1 3.43Å; L544-L547 WeakPolarHBondContact O-CG 3.32Å
545	A	40.3	Very low	66.3	Low	11 Å²	11	37.8 Å²	37.8	9%	0.091	20%	0.198	C	C	.	.	G	3₁₀ helix	trans	-64.9	-22.2	179.9	0	0	0	0	0	113.9	E55 N543	E55-A545 HydrophobicContact CB-CB 3.98Å; E55-A545 HydrophobicContact CG-CB 4.13Å; N543-A545 PolarHBondContact O-N 2.93Å; N543-A545 WeakPolarHBondContact OD1-CB 3.49Å; N543-A545 PolarHBondContact OD1-N 3.5Å
546	Y	49.4	Very low	66.6	Low	194 Å²	194	40.6 Å²	40.6	76%	0.761	22%	0.221	S	C	*	.	G	3₁₀ helix	trans	-122.9	48.1	178.6	-71	-78.4	0	0	0	112.7	L544 G548	L544-Y546 PolarHBondContact O-N 3.41Å; Y546-G548 PolarHBondContact O-N 3.41Å; Y546-G548 VanDerWaalsContact O-N 3.09Å
547	L	58	Low	67.4	Low	52 Å²	52	39.5 Å²	39.5	27%	0.272	22%	0.216	S	C	.	.			trans	-76.5	97.2	178.7	-72.1	165.4	0	0	0	111.5	T52 L544 W551	T52-L547 HydrophobicContact CG2-CD1 3.79Å; L544-L547 HydrophobicContact CB-CD1 3.64Å; L544-L547 HydrophobicContact CB-CG 4.16Å; L544-L547 HydrophobicContact CD2-CD1 3.66Å; L544-L547 HydrophobicContact CD2-CD2 3.94Å; L544-L547 HydrophobicContact CD2-CG 4.19Å; L544-L547 HydrophobicContact CG-CD1 4.22Å; L544-L547 VanDerWaalsContact O-CD1 3.24Å; L544-L547 WeakPolarHBondContact O-CD1 3.43Å; L544-L547 WeakPolarHBondContact O-CG 3.32Å; L547-W551 HydrophobicContact CB-CB 4.46Å; L547-W551 HydrophobicContact CD2-CB 3.11Å; L547-W551 HydrophobicContact CD2-CG 4.02Å; L547-W551 HydrophobicContact CG-CB 4.35Å
548	G	66.7	Low	68.4	Low	23 Å²	23	38.5 Å²	38.5	24%	0.237	21%	0.211	C	C	.	.			trans	-54.4	155.8	155.3	0	0	0	0	0	110.8	Y546 G550 W551 A552	Y546-G548 PolarHBondContact O-N 3.41Å; Y546-G548 VanDerWaalsContact O-N 3.09Å; G548-G550 PolarHBondContact O-N 3.42Å; G548-W551 PolarHBondContact O-N 3.44Å; G548-A552 PolarHBondContact O-N 3.48Å
549	V	72.8	Confident	69.1	Low	85 Å²	85	38.6 Å²	38.6	52%	0.515	21%	0.212	S	C	.	.	H	α-helix	trans	-48.5	-37.6	-176.2	177	0	0	0	0	112.6	F473 W551 A552 A553	F473-V549 HydrophobicContact CD1-CB 4.48Å; F473-V549 HydrophobicContact CD1-CG1 4.37Å; F473-V549 HydrophobicContact CE1-CG1 4.38Å; V549-W551 PolarHBondContact O-N 2.95Å; V549-A552 PolarHBondContact O-N 2.75Å; V549-A553 PolarHBondContact O-N 2.88Å
550	G	76	Confident	70	Confident	0 Å²	0	42.4 Å²	42.4	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-62.3	-38.9	179.1	0	0	0	0	0	114.1	G548 M554	G548-G550 PolarHBondContact O-N 3.42Å; G550-M554 PolarHBondContact O-N 3.21Å
551	W	76.7	Confident	71.5	Confident	23 Å²	23	40.9 Å²	40.9	9%	0.087	22%	0.224	C	C	.	.	H	α-helix	trans	-77.1	-31.9	177.8	-79.7	119.9	0	0	0	112.8	N489 H492 R493 L496 R542 L547 G548 V549 A553 M554 T555	N489-W551 PolarHBondContact OD1-NE1 3.35Å; H492-W551 AromaticContact CD2-CH2 3.79Å; R493-W551 HydrophobicContact CB-CH2 4.44Å; R493-W551 HydrophobicContact CB-CZ2 4.45Å; L496-W551 HydrophobicContact CD1-CH2 4.28Å; L496-W551 HydrophobicContact CD1-CZ3 4.16Å; R542-W551 HydrophobicContact CG-CZ3 4.46Å; L547-W551 HydrophobicContact CB-CB 4.46Å; L547-W551 HydrophobicContact CD2-CB 3.11Å; L547-W551 HydrophobicContact CD2-CG 4.02Å; L547-W551 HydrophobicContact CG-CB 4.35Å; G548-W551 PolarHBondContact O-N 3.44Å; V549-W551 PolarHBondContact O-N 2.95Å; W551-A553 VanDerWaalsContact C-N 3.34Å; W551-M554 HydrophobicContact CE3-CB 4.29Å; W551-M554 HydrophobicContact CE3-CG 4.35Å; W551-M554 HydrophobicContact CZ3-CG 4.44Å; W551-M554 PolarHBondContact O-N 2.88Å; W551-T555 WeakPolarHBondContact O-CB 3.31Å; W551-T555 PolarHBondContact O-N 3.02Å; W551-T555 PolarHBondContact O-OG1 2.91Å
552	A	76.9	Confident	72.9	Confident	47 Å²	47	36.9 Å²	36.9	39%	0.388	21%	0.209	S	C	.	.	H	α-helix	trans	-61.4	-45.2	171.6	0	0	0	0	0	110.7	G548 V549 M554 T555 A556	G548-A552 PolarHBondContact O-N 3.48Å; V549-A552 PolarHBondContact O-N 2.75Å; A552-M554 PolarHBondContact O-N 3.42Å; A552-T555 PolarHBondContact O-N 2.88Å; A552-A556 PolarHBondContact O-N 3.35Å
553	A	81.8	Confident	74.1	Confident	28 Å²	28	39.6 Å²	39.6	23%	0.231	22%	0.222	C	C	.	.	H	α-helix	trans	-61.4	-42.3	174.5	0	0	0	0	0	112.6	V469 V549 W551 A556 A557	V469-A553 HydrophobicContact CG1-CB 3.76Å; V549-A553 PolarHBondContact O-N 2.88Å; W551-A553 VanDerWaalsContact C-N 3.34Å; A553-A556 PolarHBondContact O-N 2.9Å; A553-A557 WeakPolarHBondContact O-CB 3.22Å; A553-A557 PolarHBondContact O-N 2.9Å
554	M	84	Confident	76	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-60.7	-44.9	175.9	-173.8	70.3	-154.7	0	0	111.9	V466 L496 L500 G550 W551 A552 A557 E558	V466-M554 HydrophobicContact CG1-CB 4.28Å; V466-M554 HydrophobicContact CG1-SD 3.53Å; V466-M554 VanDerWaalsContact CG1-SD 3.53Å; L496-M554 HydrophobicContact CB-CE 3.55Å; L496-M554 HydrophobicContact CB-SD 4.21Å; L500-M554 HydrophobicContact CD1-CE 3.63Å; L500-M554 HydrophobicContact CD1-SD 4.11Å; L500-M554 HydrophobicContact CG-CE 3.98Å; G550-M554 PolarHBondContact O-N 3.21Å; W551-M554 HydrophobicContact CE3-CB 4.29Å; W551-M554 HydrophobicContact CE3-CG 4.35Å; W551-M554 HydrophobicContact CZ3-CG 4.44Å; W551-M554 PolarHBondContact O-N 2.88Å; A552-M554 PolarHBondContact O-N 3.42Å; M554-A557 WeakPolarHBondContact O-CB 3.49Å; M554-A557 PolarHBondContact O-N 3.44Å; M554-E558 HydrophobicContact CE-CG 3.81Å; M554-E558 WeakPolarHBondContact CE-OE1 3.42Å; M554-E558 WeakPolarHBondContact O-CG 3.35Å; M554-E558 PolarHBondContact O-N 2.95Å
555	T	81.1	Confident	77.9	Confident	10 Å²	10	37.1 Å²	37.1	6%	0.061	21%	0.208	C	C	.	.	H	α-helix	trans	-65.9	-44.1	-179.3	-55.2	0	0	0	0	111.3	R542 W551 A552 A557 E558 I559	R542-T555 PolarHBondContact NH1-OG1 2.8Å; W551-T555 WeakPolarHBondContact O-CB 3.31Å; W551-T555 PolarHBondContact O-N 3.02Å; W551-T555 PolarHBondContact O-OG1 2.91Å; A552-T555 PolarHBondContact O-N 2.88Å; T555-A557 VanDerWaalsContact C-N 3.31Å; T555-A557 PolarHBondContact O-N 3.35Å; T555-E558 PolarHBondContact O-N 2.92Å; T555-I559 HydrophobicContact CG2-CD1 4.14Å; T555-I559 WeakPolarHBondContact O-CG1 3.36Å; T555-I559 PolarHBondContact O-N 3.35Å
556	A	83.8	Confident	79.9	Confident	59 Å²	59	37.2 Å²	37.2	49%	0.488	21%	0.207	S	C	.	.	H	α-helix	trans	-59.9	-42	174.6	0	0	0	0	0	112	A552 A553 I559 L560	A552-A556 PolarHBondContact O-N 3.35Å; A553-A556 PolarHBondContact O-N 2.9Å; A556-I559 PolarHBondContact O-N 3.47Å; A556-L560 PolarHBondContact O-N 3.31Å
557	A	88	Confident	81.7	Confident	7 Å²	7	30.7 Å²	30.7	6%	0.058	19%	0.187	C	C	.	.	H	α-helix	trans	-65.7	-37.5	177.3	0	0	0	0	0	113.3	I462 V466 L500 A553 M554 T555 L560 T561	I462-A557 HydrophobicContact CG2-CB 3.47Å; I462-A557 VanDerWaalsContact CG2-CB 3.47Å; V466-A557 HydrophobicContact CG2-CB 3.27Å; L500-A557 HydrophobicContact CD1-CB 3.98Å; A553-A557 WeakPolarHBondContact O-CB 3.22Å; A553-A557 PolarHBondContact O-N 2.9Å; M554-A557 WeakPolarHBondContact O-CB 3.49Å; M554-A557 PolarHBondContact O-N 3.44Å; T555-A557 VanDerWaalsContact C-N 3.31Å; T555-A557 PolarHBondContact O-N 3.35Å; A557-L560 PolarHBondContact O-N 3.3Å; A557-T561 VanDerWaalsContact O-CB 3.28Å; A557-T561 WeakPolarHBondContact O-CB 3.39Å; A557-T561 PolarHBondContact O-N 2.82Å; A557-T561 PolarHBondContact O-OG1 2.67Å
558	E	86.4	Confident	83.1	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-66.7	-44.2	175.3	-84.1	175.4	167.9	0	0	112.6	L500 I535 Q538 I539 R542 M554 T555 L560 T561 L562	L500-E558 HydrophobicContact CD2-CG 4.39Å; I535-E558 HydrophobicContact CG1-CG 4.26Å; I535-E558 HydrophobicContact CG2-CB 3.7Å; I535-E558 HydrophobicContact CG2-CG 4.17Å; Q538-E558 PolarHBondContact OE1-OE1 2.89Å; I539-E558 HydrophobicContact CD1-CB 4.27Å; R542-E558 IonicContact CZ-OE1 2.86Å; R542-E558 IonicContact CZ-OE2 3.68Å; R542-E558 IonicContact NH1-OE1 3.9Å; R542-E558 IonicContact NH1-OE2 3.54Å; R542-E558 PolarHBondContact NH1-OE2 2.96Å; R542-E558 IonicContact NH2-OE1 3.12Å; R542-E558 PolarHBondContact NH2-OE1 3.48Å; R542-E558 IonicContact NH2-OE2 2.71Å; R542-E558 PolarHBondContact NH2-OE2 2.82Å; M554-E558 HydrophobicContact CE-CG 3.81Å; M554-E558 WeakPolarHBondContact CE-OE1 3.42Å; M554-E558 WeakPolarHBondContact O-CG 3.35Å; M554-E558 PolarHBondContact O-N 2.95Å; T555-E558 PolarHBondContact O-N 2.92Å; E558-L560 VanDerWaalsContact C-N 3.33Å; E558-L560 PolarHBondContact O-N 3.4Å; E558-T561 CarbonylContact O-C 3.54Å; E558-T561 WeakPolarHBondContact O-CA 2.99Å; E558-T561 WeakPolarHBondContact O-CB 3.23Å; E558-T561 PolarHBondContact O-N 3.08Å; E558-T561 VanDerWaalsContact O-N 3.08Å; E558-L562 WeakPolarHBondContact O-CG 3.49Å; E558-L562 PolarHBondContact O-N 2.94Å
559	I	84.3	Confident	83.9	Confident	28 Å²	28	27.6 Å²	27.6	14%	0.144	17%	0.165	C	C	.	.	H	α-helix	trans	-58.1	-47.5	173.8	-67.5	164.2	0	0	0	110.1	L45 W70 I539 T555 A556 T561 L562 F563	L45-I559 HydrophobicContact CD1-CD1 4.29Å; W70-I559 HydrophobicContact CH2-CD1 4.21Å; W70-I559 HydrophobicContact CZ3-CD1 3.76Å; W70-I559 HydrophobicContact CZ3-CG1 4.49Å; I539-I559 HydrophobicContact CD1-CG1 4.26Å; T555-I559 HydrophobicContact CG2-CD1 4.14Å; T555-I559 WeakPolarHBondContact O-CG1 3.36Å; T555-I559 PolarHBondContact O-N 3.35Å; A556-I559 PolarHBondContact O-N 3.47Å; I559-T561 VanDerWaalsContact C-N 3.28Å; I559-T561 PolarHBondContact O-N 3.25Å; I559-L562 WeakPolarHBondContact O-CB 3.24Å; I559-L562 PolarHBondContact O-N 2.84Å; I559-F563 HydrophobicContact CG2-CD2 4.41Å; I559-F563 HydrophobicContact CG2-CE2 3.75Å; I559-F563 WeakPolarHBondContact O-CD2 3.18Å; I559-F563 PolarHBondContact O-N 3.26Å
560	L	88.2	Confident	84.3	Confident	83 Å²	83	24 Å²	24	44%	0.435	14%	0.144	S	C	.	.	H	α-helix	trans	-61.7	-38.4	175.6	-176.5	55.5	0	0	0	111.9	I462 A556 A557 E558 L562 F563 L564	I462-L560 HydrophobicContact CD1-CB 4.48Å; I462-L560 HydrophobicContact CD1-CD2 3.35Å; I462-L560 HydrophobicContact CD1-CG 3.69Å; I462-L560 HydrophobicContact CG1-CD2 4.01Å; A556-L560 PolarHBondContact O-N 3.31Å; A557-L560 PolarHBondContact O-N 3.3Å; E558-L560 VanDerWaalsContact C-N 3.33Å; E558-L560 PolarHBondContact O-N 3.4Å; L560-L562 VanDerWaalsContact C-N 3.34Å; L560-L562 PolarHBondContact O-N 3.4Å; L560-F563 PolarHBondContact O-N 3.5Å; L560-L564 HydrophobicContact CG-CD1 4.15Å; L560-L564 WeakPolarHBondContact O-CG 3.41Å; L560-L564 PolarHBondContact O-N 2.94Å; L560-L564 VanDerWaalsContact O-N 3.13Å
561	T	88.5	Confident	84.6	Confident	2 Å²	2	24.4 Å²	24.4	1%	0.012	15%	0.147	C	C	.	.	H	α-helix	trans	-65	-36.1	177.3	-61.4	0	0	0	0	111.9	Q459 L500 I535 A557 E558 I559 F563 L564 Q565	Q459-T561 HydrophobicContact CG-CG2 4.36Å; Q459-T561 PolarHBondContact NE2-O 2.73Å; L500-T561 HydrophobicContact CD2-CG2 3.93Å; I535-T561 HydrophobicContact CD1-CG2 3.69Å; A557-T561 VanDerWaalsContact O-CB 3.28Å; A557-T561 WeakPolarHBondContact O-CB 3.39Å; A557-T561 PolarHBondContact O-N 2.82Å; A557-T561 PolarHBondContact O-OG1 2.67Å; E558-T561 CarbonylContact O-C 3.54Å; E558-T561 WeakPolarHBondContact O-CA 2.99Å; E558-T561 WeakPolarHBondContact O-CB 3.23Å; E558-T561 PolarHBondContact O-N 3.08Å; E558-T561 VanDerWaalsContact O-N 3.08Å; I559-T561 VanDerWaalsContact C-N 3.28Å; I559-T561 PolarHBondContact O-N 3.25Å; T561-F563 PolarHBondContact O-N 3.01Å; T561-L564 PolarHBondContact O-N 2.99Å; T561-Q565 HydrophobicContact CG2-CG 4.1Å; T561-Q565 WeakPolarHBondContact O-CB 3.35Å; T561-Q565 WeakPolarHBondContact O-CG 3.28Å; T561-Q565 PolarHBondContact O-N 3.01Å
562	L	85.5	Confident	84.9	Confident	15 Å²	15	23.3 Å²	23.3	8%	0.079	14%	0.143	C	C	.	.	H	α-helix	trans	-55.7	-49.3	173.6	-71.1	174.1	0	0	0	111.4	V532 I535 L536 I539 E558 I559 L560 L564 Q565 F566	V532-L562 HydrophobicContact CB-CD2 4.23Å; V532-L562 HydrophobicContact CG1-CD2 4.07Å; V532-L562 HydrophobicContact CG2-CD2 4.21Å; I535-L562 HydrophobicContact CB-CD2 3.75Å; I535-L562 HydrophobicContact CB-CG 4.28Å; I535-L562 HydrophobicContact CD1-CD2 4.16Å; I535-L562 HydrophobicContact CD1-CG 4.44Å; I535-L562 HydrophobicContact CG2-CD1 3.92Å; I535-L562 HydrophobicContact CG2-CD2 3.65Å; I535-L562 HydrophobicContact CG2-CG 3.65Å; L536-L562 HydrophobicContact CD2-CD1 4.09Å; L536-L562 HydrophobicContact CG-CD2 4.33Å; I539-L562 HydrophobicContact CD1-CD1 4.48Å; E558-L562 WeakPolarHBondContact O-CG 3.49Å; E558-L562 PolarHBondContact O-N 2.94Å; I559-L562 WeakPolarHBondContact O-CB 3.24Å; I559-L562 PolarHBondContact O-N 2.84Å; L560-L562 VanDerWaalsContact C-N 3.34Å; L560-L562 PolarHBondContact O-N 3.4Å; L562-L564 VanDerWaalsContact C-N 3.34Å; L562-L564 PolarHBondContact O-N 3.19Å; L562-Q565 PolarHBondContact O-N 3.43Å; L562-F566 WeakPolarHBondContact O-CB 2.87Å; L562-F566 PolarHBondContact O-N 2.86Å
563	F	87	Confident	84.7	Confident	82 Å²	82	21 Å²	21	36%	0.36	12%	0.124	S	C	.	.	H	α-helix	trans	-63.7	-39.6	178.4	-65.3	-72	0	0	0	112.5	L76 I559 L560 T561 F566 T567	L76-F563 HydrophobicContact CB-CE1 4.28Å; L76-F563 HydrophobicContact CD1-CE1 3.88Å; L76-F563 HydrophobicContact CD1-CZ 3.62Å; I559-F563 HydrophobicContact CG2-CD2 4.41Å; I559-F563 HydrophobicContact CG2-CE2 3.75Å; I559-F563 WeakPolarHBondContact O-CD2 3.18Å; I559-F563 PolarHBondContact O-N 3.26Å; L560-F563 PolarHBondContact O-N 3.5Å; T561-F563 PolarHBondContact O-N 3.01Å; F563-F566 PolarHBondContact O-N 3.48Å; F563-T567 WeakPolarHBondContact O-CB 3.21Å; F563-T567 PolarHBondContact O-N 3.31Å; F563-T567 PolarHBondContact O-OG1 3.32Å
564	L	91	Very high	84.3	Confident	29 Å²	29	20.3 Å²	20.3	15%	0.152	12%	0.117	C	C	.	.	H	α-helix	trans	-68.7	-40.2	178.4	-68.8	171.3	0	0	0	111.6	A455 A458 Q459 I462 L560 T561 L562 T567 I568	A455-L564 HydrophobicContact CB-CD2 4.16Å; A458-L564 HydrophobicContact CB-CD1 4.1Å; A458-L564 HydrophobicContact CB-CD2 4.45Å; Q459-L564 HydrophobicContact CG-CB 3.7Å; Q459-L564 HydrophobicContact CG-CD1 3.54Å; Q459-L564 HydrophobicContact CG-CG 4.25Å; I462-L564 HydrophobicContact CD1-CD1 3.54Å; L560-L564 HydrophobicContact CG-CD1 4.15Å; L560-L564 WeakPolarHBondContact O-CG 3.41Å; L560-L564 PolarHBondContact O-N 2.94Å; L560-L564 VanDerWaalsContact O-N 3.13Å; T561-L564 PolarHBondContact O-N 2.99Å; L562-L564 VanDerWaalsContact C-N 3.34Å; L562-L564 PolarHBondContact O-N 3.19Å; L564-T567 WeakPolarHBondContact O-CB 3.42Å; L564-T567 PolarHBondContact O-N 3.33Å; L564-I568 WeakPolarHBondContact O-CG1 3.46Å; L564-I568 PolarHBondContact O-N 3.05Å
565	Q	89.2	Confident	84	Confident	1 Å²	1	20.3 Å²	20.3	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-64	-42	174.3	-72.2	-57.5	-17.1	0	0	111.1	Q459 A528 R531 V532 T561 L562 T567 I568 M569	Q459-Q565 VanDerWaalsContact NE2-CD 3.34Å; Q459-Q565 VanDerWaalsContact NE2-N 3.2Å; Q459-Q565 VanDerWaalsContact NE2-NE2 3.1Å; A528-Q565 HydrophobicContact CB-CB 4.32Å; R531-Q565 HydrophobicContact CB-CG 4.07Å; V532-Q565 HydrophobicContact CG2-CB 3.81Å; T561-Q565 HydrophobicContact CG2-CG 4.1Å; T561-Q565 WeakPolarHBondContact O-CB 3.35Å; T561-Q565 WeakPolarHBondContact O-CG 3.28Å; T561-Q565 PolarHBondContact O-N 3.01Å; L562-Q565 PolarHBondContact O-N 3.43Å; Q565-T567 VanDerWaalsContact C-N 3.32Å; Q565-T567 PolarHBondContact O-N 2.85Å; Q565-I568 PolarHBondContact O-N 2.96Å; Q565-M569 WeakPolarHBondContact O-CG 3.34Å; Q565-M569 PolarHBondContact O-N 3.12Å
566	F	83.4	Confident	83.6	Confident	13 Å²	13	21.1 Å²	21.1	6%	0.057	12%	0.12	C	C	.	.	H	α-helix	trans	-60.5	-41.4	173.6	-176.2	-99.3	0	0	0	112.8	L77 A80 L84 L96 L562 F563 I568 M569 C570	L77-F566 HydrophobicContact CB-CD2 4.03Å; L77-F566 HydrophobicContact CB-CE2 3.99Å; L77-F566 HydrophobicContact CD1-CD2 4.42Å; L77-F566 HydrophobicContact CD2-CB 3.74Å; L77-F566 HydrophobicContact CD2-CD1 4.22Å; L77-F566 HydrophobicContact CD2-CD2 3.79Å; L77-F566 HydrophobicContact CD2-CE2 4.46Å; L77-F566 HydrophobicContact CD2-CG 3.65Å; L77-F566 HydrophobicContact CG-CD2 4.3Å; L77-F566 VanDerWaalsContact O-CZ 3.31Å; L77-F566 WeakPolarHBondContact O-CZ 3.28Å; A80-F566 HydrophobicContact CB-CE1 3.62Å; A80-F566 HydrophobicContact CB-CZ 4.04Å; L84-F566 HydrophobicContact CD1-CE1 4.2Å; L84-F566 HydrophobicContact CD1-CZ 4.48Å; L96-F566 HydrophobicContact CD2-CE2 4.34Å; L562-F566 WeakPolarHBondContact O-CB 2.87Å; L562-F566 PolarHBondContact O-N 2.86Å; F563-F566 PolarHBondContact O-N 3.48Å; F566-I568 PolarHBondContact O-N 3.35Å; F566-M569 HydrophobicContact CB-CE 4.16Å; F566-M569 HydrophobicContact CD2-CE 3.7Å; F566-M569 HydrophobicContact CG-CE 4.35Å; F566-M569 PolarHBondContact O-N 2.92Å; F566-C570 VanDerWaalsContact CE1-SG 3.55Å; F566-C570 PolarHBondContact O-N 2.87Å; F566-C570 PolarHBondContact O-SG 3.44Å
567	T	87.1	Confident	82.8	Confident	57 Å²	57	18.9 Å²	18.9	35%	0.35	10%	0.1	S	C	.	.	H	α-helix	trans	-61.7	-43.1	175.1	-58.6	0	0	0	0	111.6	V451 F563 L564 Q565 C570 A571	V451-T567 HydrophobicContact CG1-CG2 3.5Å; F563-T567 WeakPolarHBondContact O-CB 3.21Å; F563-T567 PolarHBondContact O-N 3.31Å; F563-T567 PolarHBondContact O-OG1 3.32Å; L564-T567 WeakPolarHBondContact O-CB 3.42Å; L564-T567 PolarHBondContact O-N 3.33Å; Q565-T567 VanDerWaalsContact C-N 3.32Å; Q565-T567 PolarHBondContact O-N 2.85Å; T567-C570 PolarHBondContact O-N 2.82Å; T567-A571 WeakPolarHBondContact O-CB 3.11Å; T567-A571 PolarHBondContact O-N 2.87Å
568	I	87.1	Confident	81.9	Confident	0 Å²	0	19.5 Å²	19.5	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-61.3	-46.4	175.1	-69.4	167.9	0	0	0	110.6	V452 A455 I524 L564 Q565 F566 C570 A571 C572	V452-I568 HydrophobicContact CG1-CG2 4.42Å; A455-I568 HydrophobicContact CB-CD1 3.99Å; A455-I568 HydrophobicContact CB-CG1 3.63Å; I524-I568 HydrophobicContact CG2-CG2 3.4Å; L564-I568 WeakPolarHBondContact O-CG1 3.46Å; L564-I568 PolarHBondContact O-N 3.05Å; Q565-I568 PolarHBondContact O-N 2.96Å; F566-I568 PolarHBondContact O-N 3.35Å; I568-C570 VanDerWaalsContact C-N 3.34Å; I568-C570 PolarHBondContact O-N 3.32Å; I568-A571 PolarHBondContact O-N 2.99Å; I568-C572 VanDerWaalsContact O-CB 3.31Å; I568-C572 WeakPolarHBondContact O-CB 2.84Å; I568-C572 PolarHBondContact O-N 3.23Å
569	M	83.5	Confident	80.9	Confident	10 Å²	10	19.8 Å²	19.8	5%	0.049	10%	0.103	C	C	.	.	H	α-helix	trans	-56	-48.9	176.4	-69.5	-170.7	-63.8	0	0	111.2	A528 C529 V532 Q565 F566 A571 C572 A573	A528-M569 HydrophobicContact CB-CG 3.42Å; A528-M569 VanDerWaalsContact CB-CG 3.42Å; A528-M569 HydrophobicContact CB-SD 4.15Å; C529-M569 HydrophobicContact CB-SD 4.49Å; C529-M569 PolarHBondContact SG-SD 3.18Å; V532-M569 HydrophobicContact CG2-CE 4.26Å; Q565-M569 WeakPolarHBondContact O-CG 3.34Å; Q565-M569 PolarHBondContact O-N 3.12Å; F566-M569 HydrophobicContact CB-CE 4.16Å; F566-M569 HydrophobicContact CD2-CE 3.7Å; F566-M569 HydrophobicContact CG-CE 4.35Å; F566-M569 PolarHBondContact O-N 2.92Å; M569-A571 PolarHBondContact O-N 3.47Å; M569-C572 PolarHBondContact O-N 3.39Å; M569-A573 WeakPolarHBondContact O-CB 3.3Å; M569-A573 PolarHBondContact O-N 2.92Å
570	C	79.9	Confident	79.9	Confident	11 Å²	11	19.9 Å²	19.9	7%	0.074	10%	0.103	C	C	.	.	H	α-helix	trans	-63.5	-39.4	179.8	-66.7	0	0	0	0	112.9	L84 F93 F566 T567 I568 A573 V574	L84-C570 HydrophobicContact CD1-CB 4.1Å; L84-C570 WeakPolarHBondContact CD1-SG 3.29Å; F93-C570 HydrophobicContact CE1-CB 3.86Å; F93-C570 HydrophobicContact CZ-CB 4.34Å; F93-C570 WeakPolarHBondContact CZ-O 3.34Å; F566-C570 VanDerWaalsContact CE1-SG 3.55Å; F566-C570 PolarHBondContact O-N 2.87Å; F566-C570 PolarHBondContact O-SG 3.44Å; T567-C570 PolarHBondContact O-N 2.82Å; I568-C570 VanDerWaalsContact C-N 3.34Å; I568-C570 PolarHBondContact O-N 3.32Å; C570-A573 WeakPolarHBondContact O-CB 3.28Å; C570-V574 WeakPolarHBondContact O-CG2 3.33Å; C570-V574 PolarHBondContact O-N 3.48Å
571	A	83.7	Confident	78.4	Confident	7 Å²	7	21.2 Å²	21.2	6%	0.058	11%	0.111	C	C	.	.	H	α-helix	trans	-74.5	-40.1	179	0	0	0	0	0	112.2	C448 V451 V452 T567 I568 M569 A573 V574 L575	C448-A571 HydrophobicContact CB-CB 4.49Å; V451-A571 HydrophobicContact CB-CB 4.3Å; V451-A571 HydrophobicContact CG1-CB 3.95Å; V452-A571 HydrophobicContact CG2-CB 3.54Å; T567-A571 WeakPolarHBondContact O-CB 3.11Å; T567-A571 PolarHBondContact O-N 2.87Å; I568-A571 PolarHBondContact O-N 2.99Å; M569-A571 PolarHBondContact O-N 3.47Å; A571-A573 VanDerWaalsContact C-N 3.32Å; A571-V574 PolarHBondContact O-N 2.64Å; A571-L575 WeakPolarHBondContact O-CG 3.44Å; A571-L575 PolarHBondContact O-N 2.94Å; A571-L575 VanDerWaalsContact O-N 3.13Å
572	C	82.2	Confident	76.8	Confident	0 Å²	0	23.3 Å²	23.3	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-66.2	-35.5	175.2	-79	0	0	0	0	112.5	I524 I525 I568 M569 L575 F576	I524-C572 WeakPolarHBondContact CG2-SG 3.4Å; I525-C572 HydrophobicContact CD1-CB 4.17Å; I525-C572 HydrophobicContact CG1-CB 3.82Å; I568-C572 VanDerWaalsContact O-CB 3.31Å; I568-C572 WeakPolarHBondContact O-CB 2.84Å; I568-C572 PolarHBondContact O-N 3.23Å; M569-C572 PolarHBondContact O-N 3.39Å; C572-L575 WeakPolarHBondContact O-CB 3.43Å; C572-L575 PolarHBondContact O-N 3.12Å; C572-F576 WeakPolarHBondContact O-CB 2.99Å; C572-F576 PolarHBondContact O-N 3.47Å
573	A	72.3	Confident	75.2	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-57	-50	171	0	0	0	0	0	113.5	F92 M569 C570 A571 L575 F576 D577	F92-A573 HydrophobicContact CB-CB 4.35Å; F92-A573 HydrophobicContact CD1-CB 3.06Å; F92-A573 HydrophobicContact CD2-CB 4Å; F92-A573 HydrophobicContact CE1-CB 3.08Å; F92-A573 HydrophobicContact CE2-CB 4.01Å; F92-A573 HydrophobicContact CG-CB 3.54Å; F92-A573 HydrophobicContact CZ-CB 3.57Å; M569-A573 WeakPolarHBondContact O-CB 3.3Å; M569-A573 PolarHBondContact O-N 2.92Å; C570-A573 WeakPolarHBondContact O-CB 3.28Å; A571-A573 VanDerWaalsContact C-N 3.32Å; A573-L575 VanDerWaalsContact C-N 3.27Å; A573-L575 PolarHBondContact O-N 3.39Å; A573-F576 WeakPolarHBondContact O-CB 3.23Å; A573-F576 PolarHBondContact O-N 2.86Å; A573-F576 VanDerWaalsContact O-N 3.08Å; A573-D577 PolarHBondContact O-N 2.77Å
574	V	74.6	Confident	73.2	Confident	12 Å²	12	23.8 Å²	23.8	7%	0.073	13%	0.13	C	C	.	.	H	α-helix	trans	-57.6	-44.2	175.4	173.8	0	0	0	0	110.6	L88 L90 F93 C448 C570 A571 F576 D577 F578	L88-V574 HydrophobicContact CD1-CG2 4.26Å; L90-V574 HydrophobicContact CD1-CB 4.25Å; L90-V574 HydrophobicContact CD1-CG1 4.06Å; L90-V574 HydrophobicContact CD1-CG2 3.93Å; F93-V574 HydrophobicContact CE2-CG2 3.34Å; F93-V574 HydrophobicContact CZ-CG2 3.38Å; C448-V574 VanDerWaalsContact SG-CG1 3.53Å; C570-V574 WeakPolarHBondContact O-CG2 3.33Å; C570-V574 PolarHBondContact O-N 3.48Å; A571-V574 PolarHBondContact O-N 2.64Å; V574-F576 VanDerWaalsContact C-N 3.28Å; V574-F576 PolarHBondContact O-N 2.68Å; V574-D577 PolarHBondContact O-N 3.34Å; V574-F578 HydrophobicContact CG1-CD2 3.8Å; V574-F578 HydrophobicContact CG1-CE2 3.42Å; V574-F578 VanDerWaalsContact CG1-CE2 3.42Å; V574-F578 HydrophobicContact CG1-CZ 4.46Å; V574-F578 WeakPolarHBondContact O-CD2 3.35Å; V574-F578 PolarHBondContact O-N 2.97Å; V574-F578 VanDerWaalsContact O-N 3.09Å
575	L	76.6	Confident	70.9	Confident	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-63.9	-34.5	178	-68.8	171.3	0	0	0	112.3	I445 C448 V452 V514 H515 A571 C572 A573 S579	I445-L575 HydrophobicContact CB-CD2 4.34Å; I445-L575 HydrophobicContact CG1-CD2 4.41Å; I445-L575 HydrophobicContact CG2-CD2 3.91Å; C448-L575 HydrophobicContact CB-CD1 4.11Å; C448-L575 HydrophobicContact CB-CD2 3.72Å; C448-L575 HydrophobicContact CB-CG 3.71Å; V452-L575 HydrophobicContact CG2-CD1 4.32Å; V514-L575 HydrophobicContact CB-CD1 4.23Å; V514-L575 HydrophobicContact CG1-CB 4.39Å; V514-L575 HydrophobicContact CG1-CD1 4.29Å; H515-L575 HydrophobicContact CB-CD2 4.27Å; A571-L575 WeakPolarHBondContact O-CG 3.44Å; A571-L575 PolarHBondContact O-N 2.94Å; A571-L575 VanDerWaalsContact O-N 3.13Å; C572-L575 WeakPolarHBondContact O-CB 3.43Å; C572-L575 PolarHBondContact O-N 3.12Å; A573-L575 VanDerWaalsContact C-N 3.27Å; A573-L575 PolarHBondContact O-N 3.39Å; L575-S579 PolarHBondContact O-N 2.82Å
576	F	72.9	Confident	68.7	Low	27 Å²	27	30.4 Å²	30.4	12%	0.118	16%	0.161	C	C	.	.	H	α-helix	trans	-70.7	-41.3	176.4	-171.9	-102.6	0	0	0	111.6	P518 A521 C572 A573 V574 F578 S579 I580	P518-F576 HydrophobicContact CB-CD2 4.12Å; P518-F576 HydrophobicContact CB-CE2 3.64Å; A521-F576 HydrophobicContact CB-CB 4.34Å; A521-F576 HydrophobicContact CB-CD2 3.89Å; C572-F576 WeakPolarHBondContact O-CB 2.99Å; C572-F576 PolarHBondContact O-N 3.47Å; A573-F576 WeakPolarHBondContact O-CB 3.23Å; A573-F576 PolarHBondContact O-N 2.86Å; A573-F576 VanDerWaalsContact O-N 3.08Å; V574-F576 VanDerWaalsContact C-N 3.28Å; V574-F576 PolarHBondContact O-N 2.68Å; F576-F578 PolarHBondContact O-N 2.93Å; F576-S579 WeakPolarHBondContact O-CA 3.34Å; F576-S579 WeakPolarHBondContact O-CB 2.91Å; F576-S579 PolarHBondContact O-N 3.29Å; F576-I580 HydrophobicContact CD1-CD1 3.7Å; F576-I580 HydrophobicContact CE1-CD1 3.35Å; F576-I580 HydrophobicContact CE1-CG1 4.26Å; F576-I580 HydrophobicContact CZ-CD1 4.05Å; F576-I580 PolarHBondContact O-N 3.41Å; F576-I580 VanDerWaalsContact O-N 3.11Å
577	D	67.5	Low	66.7	Low	13 Å²	13	34.6 Å²	34.6	7%	0.07	18%	0.181	C	C	.	.	H	α-helix	trans	-63	-40.7	175.8	-80.3	-14.9	0	0	0	112.1	L90 F92 A573 V574 S579 I580 N581	L90-D577 WeakPolarHBondContact CB-OD2 3.25Å; L90-D577 HydrophobicContact CD1-CB 4.33Å; F92-D577 WeakPolarHBondContact CB-OD1 3Å; F92-D577 WeakPolarHBondContact CB-OD2 3.02Å; F92-D577 PolarHBondContact N-OD2 3.49Å; A573-D577 PolarHBondContact O-N 2.77Å; V574-D577 PolarHBondContact O-N 3.34Å; D577-S579 PolarHBondContact O-N 3.23Å; D577-I580 PolarHBondContact O-N 2.96Å; D577-N581 WeakPolarHBondContact O-CB 3.4Å; D577-N581 PolarHBondContact O-N 2.85Å
578	F	69.4	Low	64.3	Low	20 Å²	20	37.3 Å²	37.3	9%	0.088	19%	0.193	C	C	.	.	H	α-helix	trans	-60.6	-34.4	171.9	-77.5	-59.3	0	0	0	112.4	E441 R444 I445 V574 F576 S582	E441-F578 HydrophobicContact CB-CE1 4.2Å; E441-F578 HydrophobicContact CG-CE1 3.95Å; R444-F578 HydrophobicContact CB-CE2 4.15Å; R444-F578 HydrophobicContact CB-CZ 4.01Å; I445-F578 HydrophobicContact CD1-CB 4.09Å; I445-F578 HydrophobicContact CD1-CD1 4.44Å; I445-F578 HydrophobicContact CD1-CD2 4.2Å; I445-F578 HydrophobicContact CD1-CG 4.01Å; I445-F578 HydrophobicContact CG1-CB 4.33Å; I445-F578 HydrophobicContact CG1-CD2 3.58Å; I445-F578 HydrophobicContact CG1-CE2 3.96Å; I445-F578 HydrophobicContact CG1-CG 3.92Å; V574-F578 HydrophobicContact CG1-CD2 3.8Å; V574-F578 HydrophobicContact CG1-CE2 3.42Å; V574-F578 VanDerWaalsContact CG1-CE2 3.42Å; V574-F578 HydrophobicContact CG1-CZ 4.46Å; V574-F578 WeakPolarHBondContact O-CD2 3.35Å; V574-F578 PolarHBondContact O-N 2.97Å; V574-F578 VanDerWaalsContact O-N 3.09Å; F576-F578 PolarHBondContact O-N 2.93Å; F578-S582 WeakPolarHBondContact O-CB 3.49Å; F578-S582 PolarHBondContact O-N 3Å; F578-S582 PolarHBondContact O-OG 3.33Å
579	S	65.3	Low	62.1	Low	5 Å²	5	42.9 Å²	42.9	4%	0.035	22%	0.221	C	C	.	.	H	α-helix	trans	-63.2	-42.2	176	-153.7	0	0	0	0	111.5	I428 H515 L575 F576 D577 Y583	I428-S579 WeakPolarHBondContact CD1-OG 3.48Å; H515-S579 VanDerWaalsContact O-CB 3.24Å; H515-S579 WeakPolarHBondContact O-CB 3.01Å; H515-S579 PolarHBondContact O-OG 1.98Å; L575-S579 PolarHBondContact O-N 2.82Å; F576-S579 WeakPolarHBondContact O-CA 3.34Å; F576-S579 WeakPolarHBondContact O-CB 2.91Å; F576-S579 PolarHBondContact O-N 3.29Å; D577-S579 PolarHBondContact O-N 3.23Å; S579-Y583 WeakPolarHBondContact O-CD2 3.44Å; S579-Y583 WeakPolarHBondContact O-CE2 3.39Å
580	I	62.6	Low	60.2	Low	30 Å²	30	45.2 Å²	45.2	15%	0.154	23%	0.233	C	C	.	.	H	α-helix	trans	-73.2	-48.4	-179.2	-65.6	169.4	0	0	0	111.1	F261 F576 D577 S582 Y583	F261-I580 HydrophobicContact CZ-CG1 4.02Å; F576-I580 HydrophobicContact CD1-CD1 3.7Å; F576-I580 HydrophobicContact CE1-CD1 3.35Å; F576-I580 HydrophobicContact CE1-CG1 4.26Å; F576-I580 HydrophobicContact CZ-CD1 4.05Å; F576-I580 PolarHBondContact O-N 3.41Å; F576-I580 VanDerWaalsContact O-N 3.11Å; D577-I580 PolarHBondContact O-N 2.96Å; I580-S582 PolarHBondContact O-N 3.4Å; I580-Y583 PolarHBondContact O-N 3.15Å
581	N	57.4	Low	58.3	Low	112 Å²	112	54 Å²	54	60%	0.599	27%	0.266	S	S	*	.	H	α-helix	trans	-70.2	-13.3	-174.8	-67.8	-13.3	0	0	0	113.6	D577 Y583	D577-N581 WeakPolarHBondContact O-CB 3.4Å; D577-N581 PolarHBondContact O-N 2.85Å; N581-Y583 PolarHBondContact O-N 3.08Å
582	S	54.8	Low	56.2	Low	46 Å²	46	59.7 Å²	59.7	32%	0.322	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.7	-2.1	176.6	-61.7	0	0	0	0	113.7	F578 I580 P584	F578-S582 WeakPolarHBondContact O-CB 3.49Å; F578-S582 PolarHBondContact O-N 3Å; F578-S582 PolarHBondContact O-OG 3.33Å; I580-S582 PolarHBondContact O-N 3.4Å; S582-P584 WeakPolarHBondContact O-CD 3.43Å
583	Y	51.2	Low	54.3	Low	60 Å²	60	63.1 Å²	63.1	24%	0.235	32%	0.323	C	S	.	.			trans	-110.5	98.7	-178.6	-71.2	-81.1	0	0	0	112.3	I428 D429 S579 I580 N581 Q585 L586	I428-Y583 HydrophobicContact CB-CE2 4.07Å; I428-Y583 WeakPolarHBondContact CB-OH 3.4Å; I428-Y583 HydrophobicContact CD1-CE2 3.71Å; I428-Y583 HydrophobicContact CG2-CE1 3.72Å; I428-Y583 HydrophobicContact CG2-CE2 3.59Å; I428-Y583 WeakPolarHBondContact CG2-OH 3.42Å; D429-Y583 PolarHBondContact O-OH 3.25Å; S579-Y583 WeakPolarHBondContact O-CD2 3.44Å; S579-Y583 WeakPolarHBondContact O-CE2 3.39Å; I580-Y583 PolarHBondContact O-N 3.15Å; N581-Y583 PolarHBondContact O-N 3.08Å; Y583-Q585 PolarHBondContact O-N 3.48Å; Y583-Q585 VanDerWaalsContact O-N 3.12Å; Y583-L586 PolarHBondContact O-N 2.8Å
584	P	44.7	Very low	52.6	Low	46 Å²	46	65.9 Å²	65.9	30%	0.299	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.6	-11.5	179.5	24.2	-32.1	0	0	0	114.1	V435 S582 L586 E587	V435-P584 HydrophobicContact CG2-CG 4.34Å; S582-P584 WeakPolarHBondContact O-CD 3.43Å; P584-L586 PolarHBondContact O-N 3.21Å; P584-E587 PolarHBondContact O-N 3.41Å
585	Q	43.7	Very low	50.9	Low	132 Å²	132	69 Å²	69	62%	0.617	37%	0.366	S	S	*	.	H	α-helix	trans	-68.2	-17.7	177.1	-70.1	-173.6	-15.8	0	0	113.6	Y583 M589	Y583-Q585 PolarHBondContact O-N 3.48Å; Y583-Q585 VanDerWaalsContact O-N 3.12Å; Q585-M589 PolarHBondContact O-N 2.94Å
586	L	43.5	Very low	49.4	Very low	37 Å²	37	72.8 Å²	72.8	19%	0.194	39%	0.389	C	S	.	.	H	α-helix	trans	-74.6	-32.3	172.2	-118.7	80.4	0	0	0	112.4	A260 Y583 P584 L588 M589 D590	A260-L586 WeakPolarHBondContact O-CD1 3.38Å; Y583-L586 PolarHBondContact O-N 2.8Å; P584-L586 PolarHBondContact O-N 3.21Å; L586-L588 VanDerWaalsContact C-N 3.35Å; L586-M589 PolarHBondContact O-N 3.32Å; L586-D590 PolarHBondContact O-N 3.03Å; L586-D590 VanDerWaalsContact O-N 3.09Å
587	E	40.8	Very low	48.1	Very low	101 Å²	101	77.4 Å²	77.4	47%	0.472	42%	0.419	S	S	.	.	H	α-helix	trans	-66.1	-37.7	177.2	-70.4	-177.5	159.7	0	0	111.6	Y14 P584 Y591	Y14-E587 WeakPolarHBondContact CE2-OE1 3.39Å; P584-E587 PolarHBondContact O-N 3.41Å; E587-Y591 WeakPolarHBondContact O-CB 3.47Å; E587-Y591 PolarHBondContact O-N 3.31Å; E587-Y591 VanDerWaalsContact O-N 3.11Å
588	L	37	Very low	46.9	Very low	115 Å²	115	80.3 Å²	80.3	60%	0.602	45%	0.445	S	S	*	.	H	α-helix	trans	-72.1	-33.8	178.9	-163.1	70.2	0	0	0	112.5	L586 I592	L586-L588 VanDerWaalsContact C-N 3.35Å; L588-I592 HydrophobicContact CG-CD1 4.16Å; L588-I592 WeakPolarHBondContact O-CD1 3.49Å; L588-I592 VanDerWaalsContact O-CG1 3.23Å; L588-I592 WeakPolarHBondContact O-CG1 3.07Å; L588-I592 PolarHBondContact O-N 3.49Å
589	M	41.1	Very low	45.8	Very low	117 Å²	117	85.3 Å²	85.3	58%	0.576	47%	0.469	S	S	*	.	H	α-helix	trans	-75.9	-33.3	177.1	-71	-134.7	80.5	0	0	112.9	Q585 L586 I592 A593	Q585-M589 PolarHBondContact O-N 2.94Å; L586-M589 PolarHBondContact O-N 3.32Å; M589-I592 PolarHBondContact O-N 3.16Å; M589-A593 WeakPolarHBondContact O-CB 3.41Å; M589-A593 PolarHBondContact O-N 3.3Å
590	D	42.5	Very low	44.8	Very low	59 Å²	59	92.4 Å²	92.4	32%	0.316	50%	0.501	S	S	.	.	H	α-helix	trans	-73.6	-27.5	173.9	-77.2	-15.8	0	0	0	111.9	R194 L586 A594	R194-D590 IonicContact CZ-OD1 3.43Å; R194-D590 IonicContact CZ-OD2 3.71Å; R194-D590 IonicContact NH1-OD1 3.99Å; R194-D590 PolarHBondContact NH1-OD1 2.89Å; R194-D590 IonicContact NH1-OD2 3.39Å; R194-D590 PolarHBondContact NH1-OD2 3.09Å; R194-D590 IonicContact NH2-OD1 2.72Å; R194-D590 PolarHBondContact NH2-OD1 3.35Å; R194-D590 IonicContact NH2-OD2 3.7Å; L586-D590 PolarHBondContact O-N 3.03Å; L586-D590 VanDerWaalsContact O-N 3.09Å; D590-A594 PolarHBondContact O-N 3.42Å
591	Y	41	Very low	44	Very low	196 Å²	196	99.3 Å²	99.3	77%	0.769	53%	0.533	S	S	*	.	H	α-helix	trans	-70.9	-35.1	171.1	-164	-95	0	0	0	113	E587	E587-Y591 WeakPolarHBondContact O-CB 3.47Å; E587-Y591 PolarHBondContact O-N 3.31Å; E587-Y591 VanDerWaalsContact O-N 3.11Å
592	I	40	Very low	43.2	Very low	126 Å²	126	100.6 Å²	100.6	65%	0.646	54%	0.54	S	S	*	.	H	α-helix	trans	-82.4	-26.8	178.1	-64.8	166.1	0	0	0	111.9	L588 M589	L588-I592 HydrophobicContact CG-CD1 4.16Å; L588-I592 WeakPolarHBondContact O-CD1 3.49Å; L588-I592 VanDerWaalsContact O-CG1 3.23Å; L588-I592 WeakPolarHBondContact O-CG1 3.07Å; L588-I592 PolarHBondContact O-N 3.49Å; M589-I592 PolarHBondContact O-N 3.16Å
593	A	40.8	Very low	42.3	Very low	72 Å²	72	103.4 Å²	103.4	60%	0.595	56%	0.558	S	S	*	*	H	α-helix	trans	-93.9	-6.8	-176.8	0	0	0	0	0	114.7	M589 P595	M589-A593 WeakPolarHBondContact O-CB 3.41Å; M589-A593 PolarHBondContact O-N 3.3Å; A593-P595 WeakPolarHBondContact O-CD 3.15Å
594	A	37.9	Very low	41.8	Very low	57 Å²	57	110.4 Å²	110.4	47%	0.471	59%	0.59	S	S	.	*	S	Bend	trans	-80.5	109.2	170.2	0	0	0	0	0	108.8	D590 T596	D590-A594 PolarHBondContact O-N 3.42Å; A594-T596 PolarHBondContact O-N 3.26Å
595	P	38.3	Very low	41.6	Very low	79 Å²	79	116 Å²	116	51%	0.513	61%	0.612	S	S	.	*			trans	-62.4	115	170.7	26	-30.4	0	0	0	106.9	A593 V597	A593-P595 WeakPolarHBondContact O-CD 3.15Å; P595-V597 PolarHBondContact O-N 2.92Å
596	T	44.7	Very low	41.3	Very low	78 Å²	78	116.8 Å²	116.8	48%	0.479	62%	0.616	S	S	.	*			trans	-58.5	131.9	170.8	56.9	0	0	0	0	107.2	A594 A598 E599	A594-T596 PolarHBondContact O-N 3.26Å; T596-A598 PolarHBondContact O-N 3.09Å; T596-E599 PolarHBondContact O-N 2.99Å; T596-E599 WeakPolarHBondContact OG1-CG 3.49Å; T596-E599 PolarHBondContact OG1-OE2 3.44Å; T596-E599 VanDerWaalsContact OG1-OE2 3.08Å
597	V	45.2	Very low	41.1	Very low	125 Å²	125	120.6 Å²	120.6	76%	0.758	64%	0.643	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57.8	-12.9	-179.7	176.8	0	0	0	0	111.7	P595	P595-V597 PolarHBondContact O-N 2.92Å
598	A	42.3	Very low	41.6	Very low	73 Å²	73	120.7 Å²	120.7	60%	0.603	65%	0.65	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.1	-26	170.5	0	0	0	0	0	114.8	T596	T596-A598 PolarHBondContact O-N 3.09Å
599	E	46.8	Very low	42.2	Very low	126 Å²	126	121.9 Å²	121.9	59%	0.589	65%	0.652	S	S	*	*	H	α-helix	trans	-85.7	-22.3	-179.5	-82.6	174.7	142.2	0	0	113.6	T596 Q601 C603	T596-E599 PolarHBondContact O-N 2.99Å; T596-E599 WeakPolarHBondContact OG1-CG 3.49Å; T596-E599 PolarHBondContact OG1-OE2 3.44Å; T596-E599 VanDerWaalsContact OG1-OE2 3.08Å; E599-Q601 VanDerWaalsContact C-N 3.32Å; E599-Q601 PolarHBondContact O-N 2.85Å; E599-C603 WeakPolarHBondContact O-CB 3.33Å; E599-C603 PolarHBondContact O-N 3.34Å
600	Q	45.5	Very low	42.6	Very low	153 Å²	153	122.6 Å²	122.6	72%	0.715	66%	0.658	S	S	*	*	H	α-helix	trans	-76.8	-13	175.5	-84.5	-171.9	-25.3	0	0	114.6
601	Q	44.8	Very low	42.8	Very low	175 Å²	175	126.4 Å²	126.4	82%	0.818	68%	0.677	S	S	*	*	H	α-helix	trans	-98.7	-15.4	174.7	-85.2	179.9	-34	0	0	114.4	E599	E599-Q601 VanDerWaalsContact C-N 3.32Å; E599-Q601 PolarHBondContact O-N 2.85Å
602	N	41.5	Very low	43.4	Very low	139 Å²	139	125.6 Å²	125.6	74%	0.743	67%	0.674	S	S	*	*	H	α-helix	trans	-106.8	-8.4	-179.2	-101.9	-10.5	0	0	0	115.2	K604	N602-K604 PolarHBondContact O-N 3.45Å
603	C	36.2	Very low	44.2	Very low	105 Å²	105	122.1 Å²	122.1	71%	0.709	66%	0.661	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.5	27.7	-174.7	-124.7	0	0	0	0	115.8	E599	E599-C603 WeakPolarHBondContact O-CB 3.33Å; E599-C603 PolarHBondContact O-N 3.34Å
604	K	40.3	Very low	44.9	Very low	208 Å²	208	124.3 Å²	124.3	90%	0.904	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.8	-2.4	165.8	-90.9	-171.4	178.1	-179.1	0	113.6	N602	N602-K604 PolarHBondContact O-N 3.45Å
605	Q	41	Very low	46	Very low	162 Å²	162	127.6 Å²	127.6	76%	0.757	67%	0.668	S	S	*	*	S	Bend	trans	-138.9	116.2	176.1	-81.7	166.2	-35.2	0	0	110.4
606	Q	36.4	Very low	47.1	Very low	150 Å²	150	130.8 Å²	130.8	70%	0.701	68%	0.676	S	S	*	*			trans	68.5	113.4	160.3	-64.5	170.7	-56.9	0	0	119.9
607	P	39.2	Very low	48	Very low	117 Å²	117	134.4 Å²	134.4	76%	0.76	69%	0.685	S	S	*	*			trans	-131.3	81.4	144.9	35.4	-19.1	0	0	0	110.5
608	V	50.3	Low	48.5	Very low	103 Å²	103	131 Å²	131	62%	0.624	67%	0.67	S	S	*	*	S	Bend	trans	-134.2	-29	166.1	-178.8	0	0	0	0	111.3
609	E	50.5	Low	49.3	Very low	140 Å²	140	131.7 Å²	131.7	65%	0.654	66%	0.664	S	S	*	*	H	α-helix	trans	-80.3	-27.2	-175.6	-73	178.8	161.8	0	0	114.8	L611 Y612 S613	E609-L611 PolarHBondContact O-N 3.07Å; E609-Y612 PolarHBondContact O-N 2.9Å; E609-S613 PolarHBondContact O-N 2.83Å
610	L	50.2	Low	50.1	Low	132 Å²	132	130.4 Å²	130.4	69%	0.691	66%	0.664	S	S	*	*	H	α-helix	trans	-72.7	-28.9	-177.5	-151.5	77.7	0	0	0	112.8	S613 L614	L610-S613 PolarHBondContact O-OG 2.82Å; L610-L614 PolarHBondContact O-N 3.39Å
611	L	45	Very low	50.7	Low	138 Å²	138	130.1 Å²	130.1	72%	0.723	66%	0.663	S	S	*	*	H	α-helix	trans	-73.9	-32.5	178.9	-133.4	94.5	0	0	0	112.4	E609	E609-L611 PolarHBondContact O-N 3.07Å
612	Y	54.7	Low	51.2	Low	179 Å²	179	128.5 Å²	128.5	70%	0.702	66%	0.655	S	S	*	*	H	α-helix	trans	-71.8	-38.7	175.3	-90.4	-82.2	0	0	0	112.1	E609 L614 Q615 E616	E609-Y612 PolarHBondContact O-N 2.9Å; Y612-L614 VanDerWaalsContact C-N 3.31Å; Y612-L614 PolarHBondContact O-N 2.94Å; Y612-Q615 PolarHBondContact O-N 3.37Å; Y612-E616 PolarHBondContact O-N 3.42Å; Y612-E616 VanDerWaalsContact O-N 3.13Å
613	S	56.8	Low	51.9	Low	54 Å²	54	127.4 Å²	127.4	38%	0.378	65%	0.649	S	S	.	*	H	α-helix	trans	-68.6	-24.9	-178.8	71.6	0	0	0	0	114.8	E609 L610	E609-S613 PolarHBondContact O-N 2.83Å; L610-S613 PolarHBondContact O-OG 2.82Å
614	L	54.6	Low	52.8	Low	117 Å²	117	126.2 Å²	126.2	61%	0.613	64%	0.642	S	S	*	*	H	α-helix	trans	-86.4	-27.4	178.2	-72.4	172.7	0	0	0	112.6	L610 Y612 A618	L610-L614 PolarHBondContact O-N 3.39Å; Y612-L614 VanDerWaalsContact C-N 3.31Å; Y612-L614 PolarHBondContact O-N 2.94Å; L614-A618 PolarHBondContact O-N 2.99Å
615	Q	62.5	Low	53.4	Low	127 Å²	127	119.6 Å²	119.6	59%	0.593	63%	0.626	S	S	*	*	H	α-helix	trans	-76.9	-37.4	175.4	-160.1	158.9	-24.8	0	0	111.3	Y612 K617 A618 D619	Y612-Q615 PolarHBondContact O-N 3.37Å; Q615-K617 VanDerWaalsContact C-N 3.28Å; Q615-K617 PolarHBondContact O-N 3.38Å; Q615-A618 PolarHBondContact O-N 3.06Å; Q615-D619 PolarHBondContact O-N 2.99Å
616	E	61.4	Low	54.3	Low	145 Å²	145	117.2 Å²	117.2	68%	0.678	62%	0.622	S	S	*	*	H	α-helix	trans	-66.5	-27.3	175.4	-162.3	174.1	-167.7	0	0	113	Y612 V620	Y612-E616 PolarHBondContact O-N 3.42Å; Y612-E616 VanDerWaalsContact O-N 3.13Å; E616-V620 VanDerWaalsContact O-CG2 3.26Å; E616-V620 WeakPolarHBondContact O-CG2 3.23Å
617	K	61.8	Low	54.9	Low	155 Å²	155	117 Å²	117	67%	0.674	63%	0.626	S	S	*	*	H	α-helix	trans	-77.5	-31.5	173.4	-90.7	-176.4	175	-178.6	0	114	Q615 E621	Q615-K617 VanDerWaalsContact C-N 3.28Å; Q615-K617 PolarHBondContact O-N 3.38Å; K617-E621 PolarHBondContact O-N 3.37Å
618	A	56.4	Low	55.5	Low	54 Å²	54	120 Å²	120	45%	0.446	64%	0.643	S	S	.	*	H	α-helix	trans	-71.7	-38.6	177.7	0	0	0	0	0	111.9	L614 Q615 V620 E621 E622	L614-A618 PolarHBondContact O-N 2.99Å; Q615-A618 PolarHBondContact O-N 3.06Å; A618-V620 VanDerWaalsContact C-N 3.31Å; A618-V620 PolarHBondContact O-N 3.34Å; A618-E621 PolarHBondContact O-N 3.42Å; A618-E622 PolarHBondContact O-N 3.38Å
619	D	60	Low	55.8	Low	87 Å²	87	120.9 Å²	120.9	47%	0.465	64%	0.644	S	S	.	*	H	α-helix	trans	-72.8	-22	-179.1	-65.9	-18.4	0	0	0	113.2	Q615 N623	Q615-D619 PolarHBondContact O-N 2.99Å; D619-N623 PolarHBondContact O-ND2 3.44Å
620	V	63.4	Low	56.1	Low	98 Å²	98	119.9 Å²	119.9	59%	0.594	64%	0.643	S	S	*	*	H	α-helix	trans	-81.9	-35.4	176.6	173.9	0	0	0	0	111.8	E616 A618 S624	E616-V620 VanDerWaalsContact O-CG2 3.26Å; E616-V620 WeakPolarHBondContact O-CG2 3.23Å; A618-V620 VanDerWaalsContact C-N 3.31Å; A618-V620 PolarHBondContact O-N 3.34Å; V620-S624 PolarHBondContact O-N 3.39Å
621	E	58.2	Low	56.4	Low	148 Å²	148	119.2 Å²	119.2	69%	0.692	64%	0.641	S	S	*	*	H	α-helix	trans	-73.2	-36	176.7	-75.8	-176.5	170.8	0	0	111.9	K617 A618 N623 S624 A625	K617-E621 PolarHBondContact O-N 3.37Å; A618-E621 PolarHBondContact O-N 3.42Å; E621-N623 PolarHBondContact O-N 2.97Å; E621-S624 PolarHBondContact O-N 3.3Å; E621-S624 PolarHBondContact O-OG 3.18Å; E621-A625 PolarHBondContact O-N 3.26Å
622	E	55.3	Low	57.1	Low	140 Å²	140	118.1 Å²	118.1	65%	0.654	64%	0.636	S	S	*	*	H	α-helix	trans	-69.8	-31.9	178.7	-162.8	168	-170.9	0	0	113	A618	A618-E622 PolarHBondContact O-N 3.38Å
623	N	55.5	Low	57.2	Low	117 Å²	117	114.3 Å²	114.3	63%	0.626	63%	0.632	S	S	*	*	H	α-helix	trans	-79.5	-18.6	175.1	-77.7	-51.5	0	0	0	114	D619 E621	D619-N623 PolarHBondContact O-ND2 3.44Å; E621-N623 PolarHBondContact O-N 2.97Å
624	S	55.4	Low	57.2	Low	79 Å²	79	118.3 Å²	118.3	55%	0.552	65%	0.649	S	S	*	*	H	α-helix	trans	-81.9	-22.6	177.3	70.9	0	0	0	0	113.4	V620 E621	V620-S624 PolarHBondContact O-N 3.39Å; E621-S624 PolarHBondContact O-N 3.3Å; E621-S624 PolarHBondContact O-OG 3.18Å
625	A	53.7	Low	57.4	Low	70 Å²	70	118.4 Å²	118.4	58%	0.579	65%	0.651	S	S	*	*	S	Bend	trans	-85.8	-7	178.6	0	0	0	0	0	114.3	E621	E621-A625 PolarHBondContact O-N 3.26Å
626	V	58.5	Low	57	Low	111 Å²	111	117.8 Å²	117.8	67%	0.673	66%	0.656	S	S	*	*	S	Bend	trans	-99.7	-5	-179.9	-179.8	0	0	0	0	112.4
627	N	50.2	Low	56.7	Low	146 Å²	146	115.5 Å²	115.5	78%	0.781	65%	0.654	S	S	*	*			trans	-114.8	22.4	-179.2	-79.4	-33.7	0	0	0	114.9
628	T	51.9	Low	56.2	Low	181 Å²	181	111.9 Å²	111.9	100%	1.11	65%	0.652	S	S	*	*			trans	-134.4	0	164.3	47.5	0	0	0	0	109

Retrieved 628 of 628 residues in 1106 ms (Link to these results)

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