A0A077ZAH3_TRITR Loading...

Alpha-amylase

AlphaFold DB , UniProt , Accession A0A077ZAH3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 714 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.6Very low39.6Very low234 Ų234156.1 Ų156.1100%1.15382%0.821SS**  0115.10-85.1167.5143.900105.7
2D41.5Very low39.3Very low163 Ų163155.8 Ų155.887%0.87281%0.811SS**  trans-173.7104.1133.9-85.5-19.6000107.3
3V36.5Very low39Very low134 Ų134156.1 Ų156.181%0.81281%0.813SS**  trans-89.3129.2170.5172.60000105.5
4I40.1Very low39Very low165 Ų165155.6 Ų155.685%0.84681%0.811SS**  trans-170.8148.5161.9-99.6146.4000109.7
5P47Very low38.9Very low98 Ų98153.6 Ų153.664%0.63681%0.808SS**  -117.4166.5-110.940.1-35.7000116L7P5-L7 PolarHBondContact O-N 2.94Å
6L36.6Very low38.8Very low157 Ų157152.1 Ų152.182%0.82281%0.807SS**  trans-47.5118.1161.5-85.285.8000111.2
7L40Very low38.7Very low156 Ų156153.3 Ų153.382%0.81781%0.807SS**  trans-123.5116158.5-106.9142.7000107.8P5 I9P5-L7 PolarHBondContact O-N 2.94Å; L7-I9 PolarHBondContact O-N 2.87Å; L7-I9 VanDerWaalsContact O-N 3.16Å
8Y38.5Very low38.9Very low209 Ų209149.6 Ų149.682%0.8280%0.796SS**  trans-49.4108.2177.8-77.5-103.5000111.5L10Y8-L10 PolarHBondContact O-N 2.9Å
9I40.2Very low39Very low154 Ų154152.4 Ų152.479%0.7980%0.8SS**  trans-83.7107.6162-63.8176.1000106.1L7 C11L7-I9 PolarHBondContact O-N 2.87Å; L7-I9 VanDerWaalsContact O-N 3.16Å; I9-C11 PolarHBondContact O-N 2.8Å
10L36.7Very low39.7Very low134 Ų134145.9 Ų145.970%0.70277%0.765SS**  trans-54.4106.2164.7-88.793.2000108.3Y8 H12Y8-L10 PolarHBondContact O-N 2.9Å; L10-H12 PolarHBondContact O-N 3.44Å
11C35.5Very low40.3Very low113 Ų113142 Ų14276%0.76475%0.75SS**  trans-65.486.6158-92.10000107.8I9 L13I9-C11 PolarHBondContact O-N 2.8Å; C11-L13 PolarHBondContact O-N 3.41Å
12H36.6Very low41.1Very low152 Ų152133.3 Ų133.370%0.70471%0.711SS**  trans-64.193.4149-82.2-64.1000106.6L10 L14L10-H12 PolarHBondContact O-N 3.44Å; H12-L14 PolarHBondContact O-N 2.87Å
13L35.7Very low42.6Very low160 Ų160131.1 Ų131.184%0.83870%0.7SS**  trans-58.380.4155.8-83.9137.5000107C11 T15C11-L13 PolarHBondContact O-N 3.41Å; L13-T15 VanDerWaalsContact C-N 3.3Å; L13-T15 PolarHBondContact O-N 3.24Å
14L38.2Very low45Very low149 Ų149126.1 Ų126.178%0.7867%0.67SS**  trans-61.4105.9152.8-80.4158.2000104.4H12 V16H12-L14 PolarHBondContact O-N 2.87Å; L14-V16 PolarHBondContact O-N 3.07Å
15T38.1Very low47.7Very low126 Ų126118.2 Ų118.277%0.77363%0.63SS**  trans-50.598.216237.50000106.7L13 Q17L13-T15 VanDerWaalsContact C-N 3.3Å; L13-T15 PolarHBondContact O-N 3.24Å; T15-Q17 PolarHBondContact O-N 3.2Å
16V36.4Very low50Low130 Ų130114.4 Ų114.479%0.78860%0.604SS**  trans-66.289.4162.61790000103.8L14 S18L14-V16 PolarHBondContact O-N 3.07Å; V16-S18 PolarHBondContact O-N 2.65Å
17Q37.4Very low52.9Low172 Ų172110.9 Ų110.980%0.80458%0.583SS**  trans-54.7103.3155.6-79.1-179.7-18.500104.2T15 K19T15-Q17 PolarHBondContact O-N 3.2Å; Q17-K19 VanDerWaalsContact C-N 3.32Å; Q17-K19 PolarHBondContact O-N 2.75Å
18S43.2Very low55.5Low87 Ų87104 Ų10461%0.60855%0.548SS*.  trans-56.3105.6169.7470000105.2V16 Q20V16-S18 PolarHBondContact O-N 2.65Å; S18-Q20 PolarHBondContact O-N 2.86Å
19K40.1Very low58.3Low202 Ų20294.9 Ų94.988%0.87851%0.512SS*.  trans-59.2107.7173-81.6-175.9175.9-178.20105.8Q17 S21Q17-K19 VanDerWaalsContact C-N 3.32Å; Q17-K19 PolarHBondContact O-N 2.75Å; K19-S21 PolarHBondContact O-N 2.83Å; K19-S21 VanDerWaalsContact O-N 3.17Å
20Q52.2Low61.1Low22 Ų2288.8 Ų88.810%0.10348%0.482CS..  trans-58.8116.6174.6-162.8157.16.200106.8S18 C24 F25 C249S18-Q20 PolarHBondContact O-N 2.86Å; Q20-C24 WeakPolarHBondContact CG-SG 3.45Å; Q20-F25 HydrophobicContact CG-CE1 4.42Å; Q20-F25 HydrophobicContact CG-CE2 3.93Å; Q20-F25 HydrophobicContact CG-CZ 3.73Å; Q20-C249 PolarHBondContact NE2-SG 3.08Å
21S53Low63.9Low64 Ų6485.7 Ų85.745%0.44847%0.47SS..  trans-62.9133.1175.4-1660000107.8K19 D23 C24K19-S21 PolarHBondContact O-N 2.83Å; K19-S21 VanDerWaalsContact O-N 3.17Å; S21-D23 PolarHBondContact O-N 3.32Å; S21-D23 VanDerWaalsContact O-N 3.16Å; S21-C24 WeakPolarHBondContact O-CB 3.37Å; S21-C24 PolarHBondContact O-N 2.83Å; S21-C24 PolarHBondContact O-SG 3.24Å
22P59.8Low66.7Low52 Ų5282.7 Ų82.734%0.33845%0.451SS..G310 helixtrans-46.7-43.6176.1-29.135.7000112.5C24 F25P22-C24 PolarHBondContact O-N 3.01Å; P22-F25 PolarHBondContact O-N 2.96Å
23D72.4Confident69.5Low118 Ų11879 Ų7963%0.63144%0.436SS*.G310 helixtrans-60.9-14.7-179.4-49.1-0.3000114.4S21 F25S21-D23 PolarHBondContact O-N 3.32Å; S21-D23 VanDerWaalsContact O-N 3.16Å; D23-F25 VanDerWaalsContact C-N 3.29Å; D23-F25 PolarHBondContact O-N 2.67Å
24C88.1Confident72.5Confident28 Ų2873.6 Ų73.619%0.18941%0.406CS..G310 helixtrans-74.5-21.7-179.886.80000112.9Q20 S21 P22 D26 C249Q20-C24 WeakPolarHBondContact CG-SG 3.45Å; S21-C24 WeakPolarHBondContact O-CB 3.37Å; S21-C24 PolarHBondContact O-N 2.83Å; S21-C24 PolarHBondContact O-SG 3.24Å; P22-C24 PolarHBondContact O-N 3.01Å; C24-D26 VanDerWaalsContact C-N 3.27Å; C24-D26 PolarHBondContact O-N 2.77Å; C24-C249 HydrophobicContact CB-CB 3.78Å; C24-C249 WeakPolarHBondContact CB-SG 2.89Å; C24-C249 WeakPolarHBondContact O-CB 3.42Å; C24-C249 WeakPolarHBondContact SG-CB 3.4Å; C24-C249 CovalentContact SG-SG 2.04Å; C24-C249 PolarHBondContact SG-SG 3.11Å
25F96.5Very high75.2Confident0 Ų067.5 Ų67.50%038%0.376CS..G310 helixtrans-78.6-7.6179.5-64.8-66000113.2Q20 P22 D23 W230 L233 C249 P250 F251 I252Q20-F25 HydrophobicContact CG-CE1 4.42Å; Q20-F25 HydrophobicContact CG-CE2 3.93Å; Q20-F25 HydrophobicContact CG-CZ 3.73Å; P22-F25 PolarHBondContact O-N 2.96Å; D23-F25 VanDerWaalsContact C-N 3.29Å; D23-F25 PolarHBondContact O-N 2.67Å; F25-W230 AromaticContact CE2-CZ3 3.97Å; F25-W230 HydrophobicContact CE2-CZ3 3.97Å; F25-L233 HydrophobicContact CD2-CD1 4.48Å; F25-L233 HydrophobicContact CE1-CB 4.42Å; F25-L233 HydrophobicContact CE2-CB 4.13Å; F25-L233 HydrophobicContact CE2-CD1 4.42Å; F25-L233 HydrophobicContact CZ-CB 3.82Å; F25-C249 HydrophobicContact CD1-CB 4.24Å; F25-C249 HydrophobicContact CE1-CB 4.46Å; F25-P250 HydrophobicContact CD1-CG 4.25Å; F25-P250 WeakPolarHBondContact CD1-O 3.43Å; F25-P250 HydrophobicContact CE1-CG 4.08Å; F25-F251 CarbonylContact O-C 3.57Å; F25-F251 WeakPolarHBondContact O-CA 3.17Å; F25-I252 HydrophobicContact CB-CB 4.07Å; F25-I252 HydrophobicContact CB-CG1 3.82Å; F25-I252 HydrophobicContact CD1-CD1 4.43Å; F25-I252 HydrophobicContact CD1-CG1 3.54Å; F25-I252 HydrophobicContact CE1-CG1 4.34Å; F25-I252 HydrophobicContact CG-CG1 3.91Å; F25-I252 PolarHBondContact O-N 3.36Å
26D95.8Very high78.1Confident17 Ų1761.5 Ų61.59%0.09134%0.339CS..G310 helixtrans-85.2-12.9-177-62.7-38.8000114.5C24 G273 R274C24-D26 VanDerWaalsContact C-N 3.27Å; C24-D26 PolarHBondContact O-N 2.77Å; D26-G273 WeakPolarHBondContact OD1-CA 3.4Å; D26-R274 HydrophobicContact CB-CG 4.4Å; D26-R274 PolarHBondContact O-NE 3.48Å; D26-R274 PolarHBondContact O-NH2 2.72Å; D26-R274 PolarHBondContact OD1-N 2.96Å
27E95.8Very high81.1Confident83 Ų8355.3 Ų55.339%0.38830%0.302SS..  trans-86.4117.6-172.8-175.8-173.5-166.200111.4Q29 K248 F251E27-Q29 VanDerWaalsContact CB-NE2 3.33Å; E27-Q29 VanDerWaalsContact CD-NE2 3.28Å; E27-Q29 VanDerWaalsContact CG-NE2 3.27Å; E27-Q29 WeakPolarHBondContact O-CG 3.08Å; E27-Q29 PolarHBondContact O-N 3.44Å; E27-Q29 VanDerWaalsContact O-N 3.1Å; E27-Q29 PolarHBondContact O-NE2 2.01Å; E27-Q29 PolarHBondContact OE2-NE2 3.3Å; E27-K248 IonicContact OE1-NZ 2.71Å; E27-K248 PolarHBondContact OE1-NZ 3.38Å; E27-K248 IonicContact OE2-NZ 2.61Å; E27-K248 PolarHBondContact OE2-NZ 3.42Å; E27-F251 WeakPolarHBondContact O-CB 3.49Å
28L96.3Very high84Confident13 Ų1347.1 Ų47.17%0.06826%0.264CS..  trans-65.1-10.5-178.2-171.460.5000114.7V30 V37 A63 I119 F251 I354L28-V30 VanDerWaalsContact C-N 3.28Å; L28-V30 HydrophobicContact CB-CG2 4.04Å; L28-V30 HydrophobicContact CD2-CG2 3.5Å; L28-V30 VanDerWaalsContact CD2-CG2 3.5Å; L28-V30 HydrophobicContact CG-CG1 4.34Å; L28-V30 HydrophobicContact CG-CG2 3.7Å; L28-V30 PolarHBondContact O-N 3.29Å; L28-V37 HydrophobicContact CD1-CG2 3.93Å; L28-V37 HydrophobicContact CD2-CG2 3.88Å; L28-A63 HydrophobicContact CD1-CB 4.42Å; L28-I119 HydrophobicContact CD1-CD1 3.56Å; L28-F251 HydrophobicContact CB-CD2 4.37Å; L28-F251 HydrophobicContact CD1-CD1 3.74Å; L28-F251 HydrophobicContact CD1-CD2 4.31Å; L28-F251 HydrophobicContact CD1-CE1 3.77Å; L28-F251 HydrophobicContact CD1-CE2 4.33Å; L28-F251 HydrophobicContact CD1-CG 4.01Å; L28-F251 HydrophobicContact CD1-CZ 4.07Å; L28-I354 HydrophobicContact CB-CD1 3.98Å; L28-I354 HydrophobicContact CD1-CD1 4.34Å; L28-I354 HydrophobicContact CD2-CD1 4.11Å; L28-I354 HydrophobicContact CD2-CG1 4.42Å; L28-I354 HydrophobicContact CD2-CG2 3.82Å; L28-I354 HydrophobicContact CG-CD1 4.38Å
29Q96.9Very high86.7Confident17 Ų1743 Ų438%0.07924%0.235CC..SBendtrans62.129.6-177.9-49.4-57.1-45.200114.7E27 K117 L239 F244 C249E27-Q29 VanDerWaalsContact CB-NE2 3.33Å; E27-Q29 VanDerWaalsContact CD-NE2 3.28Å; E27-Q29 VanDerWaalsContact CG-NE2 3.27Å; E27-Q29 WeakPolarHBondContact O-CG 3.08Å; E27-Q29 PolarHBondContact O-N 3.44Å; E27-Q29 VanDerWaalsContact O-N 3.1Å; E27-Q29 PolarHBondContact O-NE2 2.01Å; E27-Q29 PolarHBondContact OE2-NE2 3.3Å; Q29-K117 WeakPolarHBondContact O-CG 3.48Å; Q29-L239 HydrophobicContact CG-CD1 3.68Å; Q29-F244 HydrophobicContact CB-CD1 4.13Å; Q29-F244 HydrophobicContact CB-CE1 3.84Å; Q29-F244 HydrophobicContact CG-CD1 4.47Å; Q29-F244 HydrophobicContact CG-CE1 4.32Å; Q29-C249 PolarHBondContact NE2-O 3.24Å
30V97.6Very high89.5Confident26 Ų2633.4 Ų33.416%0.15819%0.193CC..SBendtrans-126.1153.9175.1-58.70000110.1L28 G62 A63 K117L28-V30 VanDerWaalsContact C-N 3.28Å; L28-V30 HydrophobicContact CB-CG2 4.04Å; L28-V30 HydrophobicContact CD2-CG2 3.5Å; L28-V30 VanDerWaalsContact CD2-CG2 3.5Å; L28-V30 HydrophobicContact CG-CG1 4.34Å; L28-V30 HydrophobicContact CG-CG2 3.7Å; L28-V30 PolarHBondContact O-N 3.29Å; V30-G62 VanDerWaalsContact CG1-O 3.25Å; V30-G62 WeakPolarHBondContact CG1-O 3.29Å; V30-A63 HydrophobicContact CG1-CB 4.29Å; V30-K117 HydrophobicContact CG1-CB 4.09Å; V30-K117 HydrophobicContact CG1-CG 3.59Å
31P96.4Very high91.7Very high68 Ų6832.3 Ų32.344%0.44219%0.188SC..  trans-52.6147.9166.5-27.437.6000112.2D33 Q34P31-D33 WeakPolarHBondContact CB-OD1 3.49Å; P31-D33 PolarHBondContact O-N 2.89Å; P31-Q34 HydrophobicContact CB-CB 4.5Å; P31-Q34 CarbonylContact O-C 3.35Å; P31-Q34 PolarHBondContact O-N 3.44Å
32S94.3Very high93.8Very high51 Ų5129.3 Ų29.336%0.35717%0.167SC..G310 helixtrans-63.8-27.5-176.152.30000113.1Q34 S35 E435S32-Q34 VanDerWaalsContact C-N 3.28Å; S32-Q34 PolarHBondContact O-N 2.81Å; S32-S35 WeakPolarHBondContact O-CB 3.19Å; S32-S35 PolarHBondContact O-OG 3.04Å; S32-E435 WeakPolarHBondContact CB-OE1 3.14Å; S32-E435 VanDerWaalsContact OG-CD 3.23Å; S32-E435 PolarHBondContact OG-OE1 3.32Å
33D96.3Very high95.6Very high73 Ų7326.9 Ų26.939%0.3915%0.151SC..G310 helixtrans-79.1-217366.3-24.2000114.2P31 S431 A434P31-D33 WeakPolarHBondContact CB-OD1 3.49Å; P31-D33 PolarHBondContact O-N 2.89Å; D33-S431 VanDerWaalsContact O-CA 3.24Å; D33-S431 WeakPolarHBondContact O-CA 3.11Å; D33-S431 WeakPolarHBondContact O-CB 3.3Å; D33-S431 PolarHBondContact O-OG 3.14Å; D33-A434 HydrophobicContact CB-CB 4.04Å
34Q97Very high96.9Very high47 Ų4724.2 Ų24.222%0.2213%0.132CC..G310 helixtrans-122.228.1175.1-64-175.1-29.700112.3P31 S32 V36 G60 G62P31-Q34 HydrophobicContact CB-CB 4.5Å; P31-Q34 CarbonylContact O-C 3.35Å; P31-Q34 PolarHBondContact O-N 3.44Å; S32-Q34 VanDerWaalsContact C-N 3.28Å; S32-Q34 PolarHBondContact O-N 2.81Å; Q34-V36 PolarHBondContact O-N 3.28Å; Q34-V36 VanDerWaalsContact O-N 3.14Å; Q34-G60 CarbonylContact C-O 3.54Å; Q34-G60 WeakPolarHBondContact CA-O 3.38Å; Q34-G62 WeakPolarHBondContact O-CA 3.4Å; Q34-G62 PolarHBondContact O-N 2.82Å
35S96.4Very high97.4Very high21 Ų2122.9 Ų22.915%0.14712%0.123CC..BIsolated β-bridgetrans-82.214-169.249.30000115.3S32 R430S32-S35 WeakPolarHBondContact O-CB 3.19Å; S32-S35 PolarHBondContact O-OG 3.04Å; S35-R430 VanDerWaalsContact CB-NH2 3.27Å; S35-R430 PolarHBondContact O-NH2 3.21Å; S35-R430 PolarHBondContact OG-NE 3.05Å; S35-R430 PolarHBondContact OG-NH2 2.99Å
36V98.8Very high97.5Very high0 Ų025.2 Ų25.20%014%0.135CC..EExtended strand (participates in β ladder)trans-84.7135.9170.4-173.70000109.6Q34 G60 I61 G62 L348 P355 I357 T427 R430Q34-V36 PolarHBondContact O-N 3.28Å; Q34-V36 VanDerWaalsContact O-N 3.14Å; V36-G60 WeakPolarHBondContact CB-O 3.26Å; V36-G60 WeakPolarHBondContact CG2-O 2.99Å; V36-G60 PolarHBondContact N-O 2.55Å; V36-I61 HydrophobicContact CB-CG1 4.05Å; V36-I61 HydrophobicContact CG1-CG1 3.96Å; V36-I61 WeakPolarHBondContact O-CA 3.46Å; V36-G62 PolarHBondContact O-N 3.46Å; V36-G62 VanDerWaalsContact O-N 3.07Å; V36-L348 HydrophobicContact CG1-CD2 4.03Å; V36-L348 HydrophobicContact CG2-CD2 3.75Å; V36-P355 HydrophobicContact CG2-CG 4.27Å; V36-I357 HydrophobicContact CG1-CD1 4.41Å; V36-I357 HydrophobicContact CG1-CG1 4.35Å; V36-T427 HydrophobicContact CG1-CG2 4.38Å; V36-R430 HydrophobicContact CG2-CB 4.3Å; V36-R430 HydrophobicContact CG2-CG 3.87Å
37V98.9Very high97.6Very high0 Ų025.5 Ų25.50%014%0.137CC..EExtended strand (participates in β ladder)trans-103.6138.5171.1-173.80000109.1L28 A63 Q65 I119 I354 P355 R356 I357L28-V37 HydrophobicContact CD1-CG2 3.93Å; L28-V37 HydrophobicContact CD2-CG2 3.88Å; V37-A63 WeakPolarHBondContact CA-O 3.41Å; V37-A63 HydrophobicContact CG1-CB 4.43Å; V37-A63 HydrophobicContact CG2-CB 4.26Å; V37-Q65 HydrophobicContact CG1-CB 4.23Å; V37-I119 HydrophobicContact CG1-CD1 4.19Å; V37-I119 HydrophobicContact CG2-CD1 4.4Å; V37-I354 HydrophobicContact CG2-CG2 3.58Å; V37-P355 PolarHBondContact N-O 3.45Å; V37-R356 HydrophobicContact CB-CB 4.17Å; V37-R356 HydrophobicContact CB-CG 4.05Å; V37-R356 HydrophobicContact CG1-CG 4.02Å; V37-R356 CarbonylContact O-C 3.56Å; V37-R356 VanDerWaalsContact O-CA 3.22Å; V37-R356 WeakPolarHBondContact O-CA 3.37Å; V37-I357 PolarHBondContact O-N 3.33Å
38V98.9Very high97.8Very high0 Ų021.6 Ų21.60%012%0.119CC..EExtended strand (participates in β ladder)trans-110.2133.5166.962.10000109.8L40 L56 I61 A63 V64 Q65 I357 H418V38-L40 HydrophobicContact CG1-CD2 4.37Å; V38-L40 HydrophobicContact CG1-CG 4.18Å; V38-L40 HydrophobicContact CG2-CD2 3.82Å; V38-L40 HydrophobicContact CG2-CG 4.3Å; V38-L56 HydrophobicContact CG1-CD1 4.17Å; V38-L56 HydrophobicContact CG1-CD2 4.11Å; V38-I61 HydrophobicContact CB-CD1 4.22Å; V38-I61 HydrophobicContact CB-CG2 4.21Å; V38-I61 HydrophobicContact CG1-CD1 4.42Å; V38-I61 HydrophobicContact CG1-CG2 3.73Å; V38-A63 PolarHBondContact N-O 3.5Å; V38-V64 HydrophobicContact CG1-CB 4.48Å; V38-V64 HydrophobicContact CG1-CG2 3.83Å; V38-V64 CarbonylContact O-C 3.51Å; V38-V64 WeakPolarHBondContact O-CA 3.26Å; V38-Q65 PolarHBondContact O-N 3.11Å; V38-I357 WeakPolarHBondContact CA-O 3.14Å; V38-I357 HydrophobicContact CB-CD1 4.46Å; V38-I357 HydrophobicContact CB-CG1 4.02Å; V38-I357 HydrophobicContact CG2-CD1 4.46Å; V38-I357 HydrophobicContact CG2-CG1 4.07Å; V38-H418 HydrophobicContact CG2-CB 3.73Å
39H98.9Very high97.9Very high0 Ų021 Ų210%012%0.116CC..EExtended strand (participates in β ladder)trans-91.5102.1168.7-172.9-175.2000109.3F41 Q65 H319 R356 I357 M358 S359H39-F41 VanDerWaalsContact C-N 3.27Å; H39-F41 AromaticContact CE1-CD2 3.53Å; H39-F41 AromaticContact NE2-CD2 3.51Å; H39-F41 PolarHBondContact O-N 3.09Å; H39-F41 VanDerWaalsContact O-N 3.07Å; H39-Q65 WeakPolarHBondContact CA-O 3.16Å; H39-Q65 HydrophobicContact CB-CB 4.29Å; H39-Q65 PolarHBondContact CD2-O 2.98Å; H39-Q65 VanDerWaalsContact CD2-O 3.29Å; H39-H319 AromaticContact CE1-CG 3.95Å; H39-H319 AromaticContact CE1-ND1 3.41Å; H39-H319 PolarHBondContact CE1-ND1 3.33Å; H39-H319 AromaticContact ND1-ND1 3.83Å; H39-R356 HydrophobicContact CB-CG 4.37Å; H39-I357 PolarHBondContact N-O 3.39Å; H39-M358 HydrophobicContact CB-SD 3.87Å; H39-S359 WeakPolarHBondContact O-CB 3.25Å; H39-S359 PolarHBondContact O-N 3.1Å
40L98.8Very high98Very high1 Ų121.7 Ų21.71%0.00512%0.124CC..EExtended strand (participates in β ladder)trans-82.675.7173.1-64-177.4000109.2V38 E42 W43 I48 E51 L56 V64 Q65V38-L40 HydrophobicContact CG1-CD2 4.37Å; V38-L40 HydrophobicContact CG1-CG 4.18Å; V38-L40 HydrophobicContact CG2-CD2 3.82Å; V38-L40 HydrophobicContact CG2-CG 4.3Å; L40-E42 PolarHBondContact O-N 3.33Å; L40-W43 HydrophobicContact CB-CB 4.19Å; L40-W43 HydrophobicContact CB-CD2 4.21Å; L40-W43 HydrophobicContact CB-CG 3.87Å; L40-W43 HydrophobicContact CD1-CE3 4.44Å; L40-W43 HydrophobicContact CD2-CD2 4.23Å; L40-W43 HydrophobicContact CD2-CZ2 4.19Å; L40-I48 HydrophobicContact CB-CD1 4.4Å; L40-I48 HydrophobicContact CB-CG1 4.19Å; L40-I48 HydrophobicContact CD1-CB 4.27Å; L40-I48 HydrophobicContact CD1-CG1 3.8Å; L40-I48 HydrophobicContact CD1-CG2 4.02Å; L40-E51 HydrophobicContact CD1-CB 4.34Å; L40-E51 HydrophobicContact CD1-CG 4.02Å; L40-L56 HydrophobicContact CD1-CD1 4.44Å; L40-V64 HydrophobicContact CB-CG1 4.05Å; L40-V64 HydrophobicContact CD1-CG1 3.79Å; L40-V64 HydrophobicContact CD1-CG2 4.11Å; L40-V64 HydrophobicContact CG-CG1 3.89Å; L40-Q65 PolarHBondContact N-O 2.97Å; L40-Q65 VanDerWaalsContact N-O 3.07Å
41F98.2Very high98.1Very high0 Ų020.6 Ų20.60%012%0.117CC..THydrogen-bonded Turntrans-72.6123.7-169.6179.9-115.1000112.1H39 W43 S67 W83 Y87 H319 M358 S359 Y361 W414H39-F41 VanDerWaalsContact C-N 3.27Å; H39-F41 AromaticContact CE1-CD2 3.53Å; H39-F41 AromaticContact NE2-CD2 3.51Å; H39-F41 PolarHBondContact O-N 3.09Å; H39-F41 VanDerWaalsContact O-N 3.07Å; F41-W43 PolarHBondContact O-N 2.53Å; F41-S67 WeakPolarHBondContact CD2-OG 3.41Å; F41-W83 HydrophobicContact CE1-CB 4.46Å; F41-W83 HydrophobicContact CE1-CE3 4.46Å; F41-W83 HydrophobicContact CE2-CE3 4.25Å; F41-W83 HydrophobicContact CZ-CB 4.28Å; F41-W83 AromaticContact CZ-CD2 3.98Å; F41-W83 HydrophobicContact CZ-CD2 3.98Å; F41-W83 AromaticContact CZ-CE3 3.49Å; F41-W83 HydrophobicContact CZ-CE3 3.49Å; F41-W83 VanDerWaalsContact CZ-CE3 3.49Å; F41-W83 HydrophobicContact CZ-CG 4.35Å; F41-W83 HydrophobicContact CZ-CZ3 4.11Å; F41-Y87 AromaticContact CE2-CE2 3.95Å; F41-Y87 HydrophobicContact CE2-CE2 3.95Å; F41-H319 HydrophobicContact CD1-CB 3.92Å; F41-H319 HydrophobicContact CD2-CB 3.72Å; F41-H319 AromaticContact CD2-CG 3.97Å; F41-H319 HydrophobicContact CE1-CB 3.86Å; F41-H319 HydrophobicContact CE2-CB 3.64Å; F41-H319 AromaticContact CE2-CD2 3.6Å; F41-H319 AromaticContact CE2-CG 3.69Å; F41-H319 HydrophobicContact CG-CB 3.85Å; F41-H319 HydrophobicContact CZ-CB 3.72Å; F41-H319 AromaticContact CZ-CD2 3.9Å; F41-M358 HydrophobicContact CB-CE 4.01Å; F41-M358 HydrophobicContact CG-CE 4.45Å; F41-S359 PolarHBondContact N-O 3.23Å; F41-Y361 HydrophobicContact CD1-CD1 4.36Å; F41-Y361 AromaticContact CD1-CE1 3.83Å; F41-Y361 HydrophobicContact CD1-CE1 3.83Å; F41-Y361 AromaticContact CE1-CE1 3.7Å; F41-Y361 HydrophobicContact CE1-CE1 3.7Å; F41-W414 WeakPolarHBondContact O-CZ3 3.29Å
42E97.8Very high98.2Very high0 Ų017.3 Ų17.30%010%0.096CC..THydrogen-bonded Turntrans67.95.6-177.9-63.4-79.392.800116.3L40 S67 R86 R97 Y361 P387 W414L40-E42 PolarHBondContact O-N 3.33Å; E42-S67 PolarHBondContact N-OG 2.86Å; E42-R86 WeakPolarHBondContact OE1-CD 3.29Å; E42-R86 IonicContact OE1-CZ 3.64Å; E42-R86 IonicContact OE1-NE 2.72Å; E42-R86 PolarHBondContact OE1-NE 2.9Å; E42-R97 VanDerWaalsContact OE2-CD 3.23Å; E42-R97 WeakPolarHBondContact OE2-CD 2.95Å; E42-R97 IonicContact OE2-CZ 3.62Å; E42-R97 IonicContact OE2-NE 3.65Å; E42-R97 IonicContact OE2-NH1 2.92Å; E42-R97 PolarHBondContact OE2-NH1 3.49Å; E42-Y361 HydrophobicContact CB-CE1 4.26Å; E42-Y361 HydrophobicContact CG-CE1 3.96Å; E42-P387 HydrophobicContact CB-CB 3.71Å; E42-P387 HydrophobicContact CB-CG 4Å; E42-P387 HydrophobicContact CG-CB 4.22Å; E42-P387 HydrophobicContact CG-CG 4.25Å; E42-P387 WeakPolarHBondContact OE2-CD 3.2Å; E42-P387 VanDerWaalsContact OE2-CG 3.29Å; E42-P387 WeakPolarHBondContact OE2-CG 3.48Å; E42-W414 HydrophobicContact CB-CH2 4.25Å
43W98.6Very high98.4Very high2 Ų217.1 Ų17.11%0.0089%0.09CC..  trans-66.6151.5179.5-73.150.6000112L40 F41 D47 I48 E51 S98 S359 P400 W414 H418L40-W43 HydrophobicContact CB-CB 4.19Å; L40-W43 HydrophobicContact CB-CD2 4.21Å; L40-W43 HydrophobicContact CB-CG 3.87Å; L40-W43 HydrophobicContact CD1-CE3 4.44Å; L40-W43 HydrophobicContact CD2-CD2 4.23Å; L40-W43 HydrophobicContact CD2-CZ2 4.19Å; F41-W43 PolarHBondContact O-N 2.53Å; W43-D47 HydrophobicContact CE3-CB 3.99Å; W43-I48 HydrophobicContact CB-CD1 3.9Å; W43-I48 HydrophobicContact CB-CG1 3.67Å; W43-E51 HydrophobicContact CH2-CG 4.45Å; W43-E51 HydrophobicContact CZ3-CB 4.13Å; W43-E51 HydrophobicContact CZ3-CG 4.01Å; W43-S98 WeakPolarHBondContact O-CB 3.41Å; W43-S98 PolarHBondContact O-OG 3.13Å; W43-S359 WeakPolarHBondContact CZ2-OG 3.23Å; W43-S359 PolarHBondContact NE1-OG 3.27Å; W43-P400 HydrophobicContact CE3-CG 3.97Å; W43-P400 HydrophobicContact CH2-CB 4.16Å; W43-P400 HydrophobicContact CH2-CG 3.59Å; W43-P400 HydrophobicContact CZ2-CG 4.2Å; W43-P400 HydrophobicContact CZ3-CG 3.47Å; W43-P400 VanDerWaalsContact CZ3-CG 3.47Å; W43-W414 AromaticContact CD1-CE3 3.92Å; W43-W414 AromaticContact CD1-CH2 3.86Å; W43-W414 AromaticContact CD1-CZ3 3.38Å; W43-W414 HydrophobicContact CG-CH2 4.34Å; W43-W414 HydrophobicContact CG-CZ3 4.22Å; W43-W414 AromaticContact NE1-CE3 3.49Å; W43-W414 AromaticContact NE1-CZ3 3.46Å; W43-H418 AromaticContact CH2-CE1 3.94Å; W43-H418 AromaticContact CZ2-CE1 3.8Å
44R98.5Very high98.5Very high61 Ų6119 Ų1923%0.2310%0.1CC..  trans-72.6153.1169.3-64.1175.952-166.5-7.9111D46 D47 I48 S98 T397R44-D46 IonicContact CZ-OD2 3.37Å; R44-D46 IonicContact NH2-OD2 2.68Å; R44-D46 PolarHBondContact NH2-OD2 3.1Å; R44-D46 PolarHBondContact O-N 2.78Å; R44-D47 HydrophobicContact CB-CB 4.36Å; R44-D47 WeakPolarHBondContact CB-OD2 3.37Å; R44-D47 PolarHBondContact O-N 2.85Å; R44-I48 VanDerWaalsContact O-CG1 3.32Å; R44-I48 WeakPolarHBondContact O-CG1 3.41Å; R44-I48 PolarHBondContact O-N 3.03Å; R44-S98 WeakPolarHBondContact CA-O 3.04Å; R44-S98 WeakPolarHBondContact CB-O 3.33Å; R44-T397 VanDerWaalsContact CD-O 3.28Å; R44-T397 WeakPolarHBondContact CD-O 3.37Å; R44-T397 HydrophobicContact CG-CG2 4.18Å
45W98.8Very high98.5Very high1 Ų117.6 Ų17.60%0.0049%0.093CC..Hα-helixtrans-66.2-38.5-178.7-61.4-38.4000112.7D47 I48 A49 P69 S96 S98 G99 T100 E103 F104 M107W45-D47 VanDerWaalsContact C-N 3.3Å; W45-D47 PolarHBondContact O-N 2.79Å; W45-I48 PolarHBondContact O-N 3.21Å; W45-A49 PolarHBondContact O-N 2.83Å; W45-P69 HydrophobicContact CH2-CB 4.15Å; W45-P69 HydrophobicContact CZ2-CB 3.51Å; W45-S96 WeakPolarHBondContact CZ2-OG 3.46Å; W45-S98 VanDerWaalsContact CE2-CB 3.48Å; W45-S98 PolarHBondContact N-O 3.18Å; W45-G99 VanDerWaalsContact CE3-C 3.48Å; W45-G99 WeakPolarHBondContact CZ3-O 2.98Å; W45-T100 VanDerWaalsContact CZ3-C 3.42Å; W45-T100 WeakPolarHBondContact CZ3-O 3.41Å; W45-E103 HydrophobicContact CB-CB 4.35Å; W45-E103 HydrophobicContact CE3-CB 4.19Å; W45-F104 AromaticContact CD1-CD2 3.79Å; W45-F104 HydrophobicContact CD2-CB 3.71Å; W45-F104 AromaticContact CD2-CD2 3.71Å; W45-F104 HydrophobicContact CD2-CD2 3.71Å; W45-F104 HydrophobicContact CD2-CG 4.17Å; W45-F104 AromaticContact CE2-CD2 3.38Å; W45-F104 HydrophobicContact CE3-CB 3.51Å; W45-F104 HydrophobicContact CE3-CD2 4.36Å; W45-F104 HydrophobicContact CE3-CG 4.38Å; W45-F104 HydrophobicContact CG-CB 4.34Å; W45-F104 AromaticContact CG-CD2 3.95Å; W45-F104 HydrophobicContact CG-CD2 3.95Å; W45-F104 HydrophobicContact CH2-CB 4.02Å; W45-F104 HydrophobicContact CH2-CD2 4.37Å; W45-F104 HydrophobicContact CH2-CG 4.37Å; W45-F104 HydrophobicContact CZ2-CB 4.24Å; W45-F104 AromaticContact CZ2-CD2 3.76Å; W45-F104 HydrophobicContact CZ2-CD2 3.76Å; W45-F104 HydrophobicContact CZ2-CE2 4.45Å; W45-F104 HydrophobicContact CZ2-CG 4.2Å; W45-F104 HydrophobicContact CZ3-CB 3.66Å; W45-F104 HydrophobicContact CZ3-CG 4.46Å; W45-F104 AromaticContact NE1-CD2 3.47Å; W45-F104 AromaticContact NE1-CE2 3.95Å; W45-M107 HydrophobicContact CB-CB 3.94Å; W45-M107 HydrophobicContact CB-CG 4.28Å; W45-M107 HydrophobicContact CG-CE 4.42Å; W45-M107 WeakPolarHBondContact O-CB 3.39Å; W45-M107 WeakPolarHBondContact O-CG 3.42Å
46D98.7Very high98.7Very high48 Ų4816.6 Ų16.626%0.2579%0.086SC..Hα-helixtrans-59.2-41172.4-61.4-32.1000112.7R44 A49 A50R44-D46 IonicContact CZ-OD2 3.37Å; R44-D46 IonicContact NH2-OD2 2.68Å; R44-D46 PolarHBondContact NH2-OD2 3.1Å; R44-D46 PolarHBondContact O-N 2.78Å; D46-A49 PolarHBondContact O-N 2.68Å; D46-A50 WeakPolarHBondContact O-CB 3.39Å; D46-A50 PolarHBondContact O-N 2.97Å
47D98.8Very high98.6Very high24 Ų2420 Ų2013%0.12810%0.101CC..Hα-helixtrans-68.4-38.3179.5-63.1-36.7000110.4W43 R44 W45 A50 E51 S399W43-D47 HydrophobicContact CE3-CB 3.99Å; R44-D47 HydrophobicContact CB-CB 4.36Å; R44-D47 WeakPolarHBondContact CB-OD2 3.37Å; R44-D47 PolarHBondContact O-N 2.85Å; W45-D47 VanDerWaalsContact C-N 3.3Å; W45-D47 PolarHBondContact O-N 2.79Å; D47-A50 PolarHBondContact O-N 3Å; D47-E51 WeakPolarHBondContact O-CB 3.43Å; D47-E51 PolarHBondContact O-N 2.87Å; D47-S399 VanDerWaalsContact CG-OG 3.29Å; D47-S399 WeakPolarHBondContact OD1-CB 3.18Å; D47-S399 PolarHBondContact OD1-OG 2.86Å; D47-S399 WeakPolarHBondContact OD2-CA 3.36Å; D47-S399 PolarHBondContact OD2-OG 2.82Å; D47-S399 VanDerWaalsContact OD2-OG 3.09Å
48I98.9Very high98.5Very high1 Ų126 Ų261%0.00513%0.125CC..Hα-helixtrans-65.2-43.1174.7-65.8166.9000110.8L40 W43 R44 W45 A50 E51 C52 V64 V66 M107L40-I48 HydrophobicContact CB-CD1 4.4Å; L40-I48 HydrophobicContact CB-CG1 4.19Å; L40-I48 HydrophobicContact CD1-CB 4.27Å; L40-I48 HydrophobicContact CD1-CG1 3.8Å; L40-I48 HydrophobicContact CD1-CG2 4.02Å; W43-I48 HydrophobicContact CB-CD1 3.9Å; W43-I48 HydrophobicContact CB-CG1 3.67Å; R44-I48 VanDerWaalsContact O-CG1 3.32Å; R44-I48 WeakPolarHBondContact O-CG1 3.41Å; R44-I48 PolarHBondContact O-N 3.03Å; W45-I48 PolarHBondContact O-N 3.21Å; I48-A50 VanDerWaalsContact C-N 3.34Å; I48-A50 PolarHBondContact O-N 3.06Å; I48-E51 WeakPolarHBondContact O-CB 3.2Å; I48-E51 PolarHBondContact O-N 2.94Å; I48-E51 VanDerWaalsContact O-N 3.13Å; I48-C52 PolarHBondContact O-N 2.91Å; I48-C52 PolarHBondContact O-SG 2.99Å; I48-C52 VanDerWaalsContact O-SG 3.37Å; I48-V64 HydrophobicContact CG2-CG1 4.11Å; I48-V66 HydrophobicContact CD1-CG1 3.82Å; I48-M107 HydrophobicContact CB-CG 3.83Å; I48-M107 HydrophobicContact CB-SD 4.39Å; I48-M107 HydrophobicContact CG2-CG 3.66Å; I48-M107 HydrophobicContact CG2-SD 3.65Å
49A98.9Very high98.4Very high0 Ų026.5 Ų26.50%013%0.128CC..Hα-helixtrans-59.2-48176.800000110.9W45 D46 E51 C52 E53 M107 R110W45-A49 PolarHBondContact O-N 2.83Å; D46-A49 PolarHBondContact O-N 2.68Å; A49-E51 VanDerWaalsContact C-N 3.3Å; A49-E51 PolarHBondContact O-N 3.43Å; A49-C52 WeakPolarHBondContact O-CB 3.26Å; A49-C52 PolarHBondContact O-N 2.85Å; A49-E53 WeakPolarHBondContact O-CG 3.46Å; A49-E53 PolarHBondContact O-N 3.44Å; A49-M107 HydrophobicContact CB-CB 4.04Å; A49-M107 HydrophobicContact CB-CG 4.09Å; A49-R110 HydrophobicContact CB-CB 4.29Å
50A98.8Very high98.4Very high31 Ų3126.5 Ų26.526%0.25613%0.128SC..Hα-helixtrans-64-34174.800000112.3D46 D47 I48 N54D46-A50 WeakPolarHBondContact O-CB 3.39Å; D46-A50 PolarHBondContact O-N 2.97Å; D47-A50 PolarHBondContact O-N 3Å; I48-A50 VanDerWaalsContact C-N 3.34Å; I48-A50 PolarHBondContact O-N 3.06Å; A50-N54 WeakPolarHBondContact O-CB 3.46Å; A50-N54 VanDerWaalsContact O-CG 3.32Å; A50-N54 PolarHBondContact O-N 2.92Å; A50-N54 PolarHBondContact O-ND2 3.4Å
51E98.8Very high98.4Very high3 Ų326.5 Ų26.51%0.01413%0.128CC..Hα-helixtrans-68.1-41.5177-170.464.1-167.300111.7L40 W43 D47 I48 A49 E53 Y55 L56 H418 R419L40-E51 HydrophobicContact CD1-CB 4.34Å; L40-E51 HydrophobicContact CD1-CG 4.02Å; W43-E51 HydrophobicContact CH2-CG 4.45Å; W43-E51 HydrophobicContact CZ3-CB 4.13Å; W43-E51 HydrophobicContact CZ3-CG 4.01Å; D47-E51 WeakPolarHBondContact O-CB 3.43Å; D47-E51 PolarHBondContact O-N 2.87Å; I48-E51 WeakPolarHBondContact O-CB 3.2Å; I48-E51 PolarHBondContact O-N 2.94Å; I48-E51 VanDerWaalsContact O-N 3.13Å; A49-E51 VanDerWaalsContact C-N 3.3Å; A49-E51 PolarHBondContact O-N 3.43Å; E51-E53 PolarHBondContact O-N 3.29Å; E51-Y55 WeakPolarHBondContact O-CB 3.41Å; E51-Y55 PolarHBondContact O-N 2.86Å; E51-Y55 VanDerWaalsContact OE1-CD1 3.25Å; E51-Y55 WeakPolarHBondContact OE1-CD1 3.23Å; E51-L56 HydrophobicContact CG-CD1 4.13Å; E51-L56 HydrophobicContact CG-CD2 4.46Å; E51-L56 HydrophobicContact CG-CG 4.03Å; E51-L56 PolarHBondContact O-N 2.83Å; E51-H418 IonicContact OE1-CD2 2.7Å; E51-H418 PolarHBondContact OE1-CD2 3.15Å; E51-H418 IonicContact OE1-CE1 3.56Å; E51-H418 IonicContact OE1-NE2 3.43Å; E51-H418 PolarHBondContact OE1-NE2 2.89Å; E51-R419 VanDerWaalsContact CD-NH2 3.33Å; E51-R419 IonicContact OE1-CZ 3.82Å; E51-R419 IonicContact OE1-NE 3.51Å; E51-R419 PolarHBondContact OE1-NE 2.96Å; E51-R419 IonicContact OE1-NH2 3.32Å; E51-R419 PolarHBondContact OE1-NH2 3.41Å; E51-R419 IonicContact OE2-CZ 2.61Å; E51-R419 VanDerWaalsContact OE2-CZ 3.31Å; E51-R419 IonicContact OE2-NE 2.8Å; E51-R419 PolarHBondContact OE2-NE 2.81Å; E51-R419 VanDerWaalsContact OE2-NE 3.14Å; E51-R419 IonicContact OE2-NH2 3.17Å; E51-R419 PolarHBondContact OE2-NH2 3.21Å
52C98.9Very high98.4Very high0 Ų026.5 Ų26.50%013%0.128CC..Hα-helixtrans-55.2-51.7172.9-72.70000111I48 A49 Q57 C111 V114 I116I48-C52 PolarHBondContact O-N 2.91Å; I48-C52 PolarHBondContact O-SG 2.99Å; I48-C52 VanDerWaalsContact O-SG 3.37Å; A49-C52 WeakPolarHBondContact O-CB 3.26Å; A49-C52 PolarHBondContact O-N 2.85Å; C52-Q57 PolarHBondContact O-N 2.86Å; C52-Q57 VanDerWaalsContact O-N 3.15Å; C52-C111 HydrophobicContact CB-CB 3.85Å; C52-C111 WeakPolarHBondContact CB-SG 3.35Å; C52-C111 WeakPolarHBondContact SG-CB 3.33Å; C52-C111 CovalentContact SG-SG 2.05Å; C52-C111 PolarHBondContact SG-SG 2.87Å; C52-V114 HydrophobicContact CB-CG2 3.95Å; C52-I116 HydrophobicContact CB-CB 4.46Å; C52-I116 HydrophobicContact CB-CG1 4.37Å
53E98.7Very high98.5Very high47 Ų4726.5 Ų26.522%0.2213%0.128CC..Hα-helixtrans-72.7-47.1-176.7-66.8168.4165.700112.8A49 E51 Q57 R110 V114A49-E53 WeakPolarHBondContact O-CG 3.46Å; A49-E53 PolarHBondContact O-N 3.44Å; E51-E53 PolarHBondContact O-N 3.29Å; E53-Q57 WeakPolarHBondContact O-CG 3.47Å; E53-Q57 PolarHBondContact O-NE2 3.31Å; E53-R110 WeakPolarHBondContact OE1-CB 3.21Å; E53-R110 IonicContact OE1-CZ 3.83Å; E53-R110 IonicContact OE1-NE 3.39Å; E53-R110 PolarHBondContact OE1-NE 3.24Å; E53-R110 IonicContact OE1-NH2 2.93Å; E53-R110 PolarHBondContact OE1-NH2 3.08Å; E53-R110 IonicContact OE2-CZ 2.72Å; E53-R110 IonicContact OE2-NE 3.46Å; E53-R110 IonicContact OE2-NH2 3.28Å; E53-R110 PolarHBondContact OE2-NH2 3.47Å; E53-V114 HydrophobicContact CG-CG1 4.32Å
54N98Very high98.5Very high113 Ų11326.4 Ų26.460%0.60413%0.127SC*.Hα-helixtrans-88-15-169-62.5-55.6000113A50A50-N54 WeakPolarHBondContact O-CB 3.46Å; A50-N54 VanDerWaalsContact O-CG 3.32Å; A50-N54 PolarHBondContact O-N 2.92Å; A50-N54 PolarHBondContact O-ND2 3.4Å
55Y98.3Very high98.5Very high17 Ų1723.6 Ų23.67%0.06712%0.117CC..THydrogen-bonded Turntrans-138.9-60.9-172.1-174.3-99.2000114E51 Q57 Y58 T59 H418 R419 R424E51-Y55 WeakPolarHBondContact O-CB 3.41Å; E51-Y55 PolarHBondContact O-N 2.86Å; E51-Y55 VanDerWaalsContact OE1-CD1 3.25Å; E51-Y55 WeakPolarHBondContact OE1-CD1 3.23Å; Y55-Q57 VanDerWaalsContact C-N 3.33Å; Y55-Q57 PolarHBondContact O-N 2.83Å; Y55-Y58 PolarHBondContact O-N 3.13Å; Y55-T59 HydrophobicContact CD1-CG2 4.33Å; Y55-T59 HydrophobicContact CE1-CG2 3.93Å; Y55-H418 AromaticContact CE1-CD2 3.83Å; Y55-H418 PolarHBondContact OH-O 2.78Å; Y55-R419 HydrophobicContact CD1-CG 4.1Å; Y55-R419 HydrophobicContact CD2-CG 4.29Å; Y55-R419 HydrophobicContact CE1-CG 3.77Å; Y55-R419 HydrophobicContact CE2-CG 3.96Å; Y55-R419 HydrophobicContact CG-CG 4.37Å; Y55-R419 WeakPolarHBondContact OH-CA 3.32Å; Y55-R424 HydrophobicContact CE2-CG 4.47Å; Y55-R424 WeakPolarHBondContact OH-CB 3.38Å; Y55-R424 VanDerWaalsContact OH-CD 3.3Å; Y55-R424 WeakPolarHBondContact OH-CD 3.03Å; Y55-R424 WeakPolarHBondContact OH-CG 3.32Å
56L98.6Very high98.5Very high0 Ų023.6 Ų23.60%012%0.117CC..G310 helixtrans-62.9-36.4-166.9-60174.9000113.1V38 L40 E51 Y58 T59 I61 V64 I116V38-L56 HydrophobicContact CG1-CD1 4.17Å; V38-L56 HydrophobicContact CG1-CD2 4.11Å; L40-L56 HydrophobicContact CD1-CD1 4.44Å; E51-L56 HydrophobicContact CG-CD1 4.13Å; E51-L56 HydrophobicContact CG-CD2 4.46Å; E51-L56 HydrophobicContact CG-CG 4.03Å; E51-L56 PolarHBondContact O-N 2.83Å; L56-Y58 PolarHBondContact O-N 3.24Å; L56-T59 WeakPolarHBondContact O-CB 3.43Å; L56-T59 PolarHBondContact O-N 2.88Å; L56-T59 PolarHBondContact O-OG1 2.87Å; L56-I61 HydrophobicContact CD2-CB 4.39Å; L56-I61 HydrophobicContact CD2-CD1 3.65Å; L56-I61 HydrophobicContact CD2-CG2 4.25Å; L56-V64 HydrophobicContact CD1-CG2 3.46Å; L56-V64 VanDerWaalsContact CD1-CG2 3.46Å; L56-I116 HydrophobicContact CB-CD1 3.98Å; L56-I116 HydrophobicContact CB-CG1 4.19Å
57Q97.5Very high98.5Very high70 Ų7021.4 Ų21.433%0.32711%0.106SC..G310 helixtrans-58.6-18.1177.572.2165.2-65.600113.9C52 E53 Y55 V114C52-Q57 PolarHBondContact O-N 2.86Å; C52-Q57 VanDerWaalsContact O-N 3.15Å; E53-Q57 WeakPolarHBondContact O-CG 3.47Å; E53-Q57 PolarHBondContact O-NE2 3.31Å; Y55-Q57 VanDerWaalsContact C-N 3.33Å; Y55-Q57 PolarHBondContact O-N 2.83Å; Q57-V114 HydrophobicContact CB-CB 3.89Å; Q57-V114 HydrophobicContact CB-CG2 4.23Å
58Y97Very high98.5Very high128 Ų12820.3 Ų20.350%0.50210%0.1SC..G310 helixtrans-10122.9178.5-49.5-62.3000112.8Y55 L56Y55-Y58 PolarHBondContact O-N 3.13Å; L56-Y58 PolarHBondContact O-N 3.24Å
59T97.7Very high98.5Very high9 Ų920.2 Ų20.26%0.05510%0.099CC..THydrogen-bonded Turntrans-131.4-179.3-177.675.10000111.2Y55 L56 I61 R424Y55-T59 HydrophobicContact CD1-CG2 4.33Å; Y55-T59 HydrophobicContact CE1-CG2 3.93Å; L56-T59 WeakPolarHBondContact O-CB 3.43Å; L56-T59 PolarHBondContact O-N 2.88Å; L56-T59 PolarHBondContact O-OG1 2.87Å; T59-I61 VanDerWaalsContact C-N 3.25Å; T59-I61 WeakPolarHBondContact OG1-CB 3.3Å; T59-I61 PolarHBondContact OG1-N 2.63Å; T59-I61 VanDerWaalsContact OG1-N 3.12Å; T59-R424 HydrophobicContact CG2-CG 4.14Å
60G97.7Very high98.5Very high0 Ų020.2 Ų20.20%010%0.099CC..THydrogen-bonded Turntrans-86.613.2170.200000114.3Q34 V36 T427Q34-G60 CarbonylContact C-O 3.54Å; Q34-G60 WeakPolarHBondContact CA-O 3.38Å; V36-G60 WeakPolarHBondContact CB-O 3.26Å; V36-G60 WeakPolarHBondContact CG2-O 2.99Å; V36-G60 PolarHBondContact N-O 2.55Å; G60-T427 PolarHBondContact N-OG1 2.68Å
61I98.8Very high98.5Very high1 Ų118.8 Ų18.81%0.0059%0.087CC..EExtended strand (participates in β ladder)trans-87.9126.9178.9-61.4163.8000108.6V36 V38 L56 T59 A63 I116 I357 T427V36-I61 HydrophobicContact CB-CG1 4.05Å; V36-I61 HydrophobicContact CG1-CG1 3.96Å; V36-I61 WeakPolarHBondContact O-CA 3.46Å; V38-I61 HydrophobicContact CB-CD1 4.22Å; V38-I61 HydrophobicContact CB-CG2 4.21Å; V38-I61 HydrophobicContact CG1-CD1 4.42Å; V38-I61 HydrophobicContact CG1-CG2 3.73Å; L56-I61 HydrophobicContact CD2-CB 4.39Å; L56-I61 HydrophobicContact CD2-CD1 3.65Å; L56-I61 HydrophobicContact CD2-CG2 4.25Å; T59-I61 VanDerWaalsContact C-N 3.25Å; T59-I61 WeakPolarHBondContact OG1-CB 3.3Å; T59-I61 PolarHBondContact OG1-N 2.63Å; T59-I61 VanDerWaalsContact OG1-N 3.12Å; I61-A63 WeakPolarHBondContact CG2-O 3.25Å; I61-I116 WeakPolarHBondContact O-CD1 3.41Å; I61-I357 HydrophobicContact CD1-CD1 4.02Å; I61-T427 HydrophobicContact CD1-CG2 4.32Å; I61-T427 HydrophobicContact CG1-CG2 4.12Å
62G98.7Very high98.4Very high0 Ų018.8 Ų18.80%09%0.087CC..EExtended strand (participates in β ladder)trans-114.2-12.1177.700000113.6V30 Q34 V36 I116 K117V30-G62 VanDerWaalsContact CG1-O 3.25Å; V30-G62 WeakPolarHBondContact CG1-O 3.29Å; Q34-G62 WeakPolarHBondContact O-CA 3.4Å; Q34-G62 PolarHBondContact O-N 2.82Å; V36-G62 PolarHBondContact O-N 3.46Å; V36-G62 VanDerWaalsContact O-N 3.07Å; G62-I116 CarbonylContact O-C 3.54Å; G62-I116 WeakPolarHBondContact O-CA 3.3Å; G62-K117 PolarHBondContact O-N 2.95Å
63A98.9Very high98.3Very high0 Ų018.8 Ų18.80%09%0.087CC..EExtended strand (participates in β ladder)trans-141.4147.1178.800000113.5L28 V30 V37 V38 I61 K117 I119L28-A63 HydrophobicContact CD1-CB 4.42Å; V30-A63 HydrophobicContact CG1-CB 4.29Å; V37-A63 WeakPolarHBondContact CA-O 3.41Å; V37-A63 HydrophobicContact CG1-CB 4.43Å; V37-A63 HydrophobicContact CG2-CB 4.26Å; V38-A63 PolarHBondContact N-O 3.5Å; I61-A63 WeakPolarHBondContact CG2-O 3.25Å; A63-K117 CarbonylContact C-O 3.52Å; A63-K117 WeakPolarHBondContact CA-O 3.15Å; A63-K117 HydrophobicContact CB-CB 4.15Å; A63-I119 HydrophobicContact CB-CD1 3.86Å; A63-I119 HydrophobicContact CB-CG1 4.39Å
64V98.9Very high98.1Very high0 Ų018.4 Ų18.40%09%0.088CC..EExtended strand (participates in β ladder)trans-110.5122.4172.8173.70000108.2V38 L40 I48 L56 V66 I116 K117 I118 I119V38-V64 HydrophobicContact CG1-CB 4.48Å; V38-V64 HydrophobicContact CG1-CG2 3.83Å; V38-V64 CarbonylContact O-C 3.51Å; V38-V64 WeakPolarHBondContact O-CA 3.26Å; L40-V64 HydrophobicContact CB-CG1 4.05Å; L40-V64 HydrophobicContact CD1-CG1 3.79Å; L40-V64 HydrophobicContact CD1-CG2 4.11Å; L40-V64 HydrophobicContact CG-CG1 3.89Å; I48-V64 HydrophobicContact CG2-CG1 4.11Å; L56-V64 HydrophobicContact CD1-CG2 3.46Å; L56-V64 VanDerWaalsContact CD1-CG2 3.46Å; V64-V66 HydrophobicContact CG1-CG1 3.81Å; V64-I116 HydrophobicContact CG2-CG2 3.76Å; V64-K117 PolarHBondContact N-O 3.23Å; V64-I118 HydrophobicContact CB-CD1 3.97Å; V64-I119 PolarHBondContact O-N 2.92Å
65Q98.9Very high97.8Very high2 Ų215.9 Ų15.91%0.0097%0.072CC..EExtended strand (participates in β ladder)trans-81.3124.9159.4-177.1-177.9-38.500108.3V37 V38 H39 L40 I119 D121V37-Q65 HydrophobicContact CG1-CB 4.23Å; V38-Q65 PolarHBondContact O-N 3.11Å; H39-Q65 WeakPolarHBondContact CA-O 3.16Å; H39-Q65 HydrophobicContact CB-CB 4.29Å; H39-Q65 PolarHBondContact CD2-O 2.98Å; H39-Q65 VanDerWaalsContact CD2-O 3.29Å; L40-Q65 PolarHBondContact N-O 2.97Å; L40-Q65 VanDerWaalsContact N-O 3.07Å; Q65-I119 CarbonylContact C-O 3.52Å; Q65-I119 VanDerWaalsContact CA-O 3.28Å; Q65-I119 WeakPolarHBondContact CA-O 3.24Å; Q65-D121 PolarHBondContact NE2-OD2 2.94Å
66V98.9Very high97.4Very high1 Ų118.8 Ų18.81%0.0069%0.086CC..EExtended strand (participates in β ladder)trans-102.5152.5173.3-55.90000110.2I48 V64 F104 M107 I118 I119 V120 D121I48-V66 HydrophobicContact CD1-CG1 3.82Å; V64-V66 HydrophobicContact CG1-CG1 3.81Å; V66-F104 HydrophobicContact CG2-CE2 4.25Å; V66-M107 HydrophobicContact CG1-CE 4.24Å; V66-I118 HydrophobicContact CG1-CG2 4.07Å; V66-I118 HydrophobicContact CG2-CG2 4.21Å; V66-I119 PolarHBondContact N-O 3.44Å; V66-V120 HydrophobicContact CG2-CB 4.46Å; V66-V120 HydrophobicContact CG2-CG2 3.87Å; V66-D121 WeakPolarHBondContact O-CB 3.25Å; V66-D121 PolarHBondContact O-N 2.85Å
67S98.6Very high96.7Very high3 Ų319 Ų192%0.0219%0.087CC..PPolyproline II helixtrans-66.3163.6172.4-48.90000111.6F41 E42 P69F41-S67 WeakPolarHBondContact CD2-OG 3.41Å; E42-S67 PolarHBondContact N-OG 2.86Å; S67-P69 WeakPolarHBondContact O-CD 3.26Å; S67-P69 VanDerWaalsContact O-N 3.15Å
68P98.7Very high96Very high0 Ų020.5 Ų20.50%010%0.097CC..PPolyproline II helixtrans-53.7119.4-173.8-27.533.4000113.1N70 R86 Y87 D121 V123P68-N70 VanDerWaalsContact C-N 3.3Å; P68-N70 PolarHBondContact O-N 2.92Å; P68-R86 HydrophobicContact CB-CG 4.08Å; P68-R86 HydrophobicContact CG-CG 4.22Å; P68-R86 WeakPolarHBondContact O-CD 3.37Å; P68-R86 PolarHBondContact O-NH1 2.03Å; P68-Y87 HydrophobicContact CG-CD1 3.88Å; P68-Y87 HydrophobicContact CG-CD2 4.43Å; P68-Y87 HydrophobicContact CG-CE1 3.67Å; P68-Y87 HydrophobicContact CG-CE2 4.23Å; P68-Y87 HydrophobicContact CG-CG 4.25Å; P68-D121 VanDerWaalsContact CA-O 3.23Å; P68-D121 WeakPolarHBondContact CA-O 3.3Å; P68-D121 WeakPolarHBondContact CB-O 3.48Å; P68-D121 HydrophobicContact CG-CB 4.09Å; P68-V123 HydrophobicContact CB-CG2 4.04Å; P68-V123 HydrophobicContact CG-CG2 3.62Å
69P98.6Very high95.5Very high0 Ų016.7 Ų16.70%010%0.098CC..  trans-82.3-13.4-171.132.9-37.8000113.3W45 S67 L94 F104 V120 L208W45-P69 HydrophobicContact CH2-CB 4.15Å; W45-P69 HydrophobicContact CZ2-CB 3.51Å; S67-P69 WeakPolarHBondContact O-CD 3.26Å; S67-P69 VanDerWaalsContact O-N 3.15Å; P69-L94 HydrophobicContact CB-CD2 4.18Å; P69-L94 HydrophobicContact CG-CD2 4.08Å; P69-F104 HydrophobicContact CB-CD2 4.44Å; P69-F104 HydrophobicContact CB-CE2 4.12Å; P69-F104 HydrophobicContact CB-CZ 4.26Å; P69-F104 HydrophobicContact CG-CZ 4.39Å; P69-V120 HydrophobicContact CG-CG1 3.75Å; P69-V120 HydrophobicContact CG-CG2 4.27Å; P69-L208 HydrophobicContact CG-CD1 4.5Å; P69-L208 HydrophobicContact CG-CD2 4.16Å
70N98.6Very high95.1Very high0 Ų017.3 Ų17.30%010%0.101CC..SBendtrans-68.9161.5-176.663.9-91.3000112.8P68 H72 P89 S91 K93 Y204P68-N70 VanDerWaalsContact C-N 3.3Å; P68-N70 PolarHBondContact O-N 2.92Å; N70-H72 PolarHBondContact O-N 3.34Å; N70-P89 WeakPolarHBondContact ND2-CB 3.19Å; N70-S91 WeakPolarHBondContact CB-O 3.11Å; N70-K93 CarbonylContact C-O 3.51Å; N70-K93 WeakPolarHBondContact CA-O 3.49Å; N70-Y204 HydrophobicContact CB-CE2 4.31Å
71E98.7Very high94.8Very high0 Ų020.1 Ų20.10%011%0.111CC..  trans-58133.2171.2-178.8-178.9-162.600110.6P89 V90 S91 K93 E95 G136 G138 G139 S140E71-P89 WeakPolarHBondContact O-CA 3.32Å; E71-V90 HydrophobicContact CG-CB 4.06Å; E71-V90 HydrophobicContact CG-CG1 4.34Å; E71-V90 PolarHBondContact O-N 2.9Å; E71-S91 VanDerWaalsContact OE2-CB 3.32Å; E71-S91 WeakPolarHBondContact OE2-CB 3.39Å; E71-S91 PolarHBondContact OE2-OG 3.09Å; E71-K93 HydrophobicContact CB-CB 4.2Å; E71-K93 PolarHBondContact N-O 3.35Å; E71-E95 WeakPolarHBondContact CA-O 3.34Å; E71-G136 VanDerWaalsContact OE1-C 3.26Å; E71-G136 VanDerWaalsContact OE1-CA 3.27Å; E71-G136 WeakPolarHBondContact OE1-CA 3.49Å; E71-G138 VanDerWaalsContact CG-N 3.34Å; E71-G138 VanDerWaalsContact OE1-CA 3.27Å; E71-G138 WeakPolarHBondContact OE1-CA 3.42Å; E71-G138 PolarHBondContact OE1-N 2.84Å; E71-G139 PolarHBondContact OE1-N 3.03Å; E71-G139 VanDerWaalsContact OE1-N 3.12Å; E71-S140 WeakPolarHBondContact OE1-CB 3.1Å; E71-S140 PolarHBondContact OE1-N 3.09Å; E71-S140 PolarHBondContact OE1-OG 2.82Å; E71-S140 WeakPolarHBondContact OE2-CB 3.32Å; E71-S140 PolarHBondContact OE2-OG 2.93Å
72H97.8Very high94.4Very high3 Ų320 Ų201%0.01411%0.111CC..BIsolated β-bridgetrans-130.4167.1-175.26768000111.6N70 L85 Q88 R97 G136 S137N70-H72 PolarHBondContact O-N 3.34Å; H72-L85 WeakPolarHBondContact CB-O 3.38Å; H72-Q88 CarbonylContact C-O 3.58Å; H72-Q88 VanDerWaalsContact CA-O 3.28Å; H72-Q88 WeakPolarHBondContact CA-O 3.27Å; H72-R97 PolarHBondContact NE2-N 3.04Å; H72-G136 CarbonylContact O-C 3.55Å; H72-G136 VanDerWaalsContact O-CA 3.29Å; H72-G136 WeakPolarHBondContact O-CA 3.48Å; H72-S137 PolarHBondContact N-OG 2.8Å; H72-S137 PolarHBondContact O-N 2.93Å; H72-S137 PolarHBondContact O-OG 3.46Å
73I96.5Very high94.2Very high0 Ų020.7 Ų20.70%011%0.113CC..BIsolated β-bridgetrans-64.1147.9177.3-159.7167.7000111.4F75 L85 Q88 V90 T128 M132 Y142I73-F75 HydrophobicContact CD1-CD1 4.03Å; I73-F75 HydrophobicContact CD1-CE1 3.69Å; I73-F75 HydrophobicContact CG1-CD1 3.87Å; I73-F75 HydrophobicContact CG1-CE1 3.91Å; I73-F75 HydrophobicContact CG2-CD1 4.26Å; I73-F75 HydrophobicContact CG2-CE1 3.82Å; I73-L85 HydrophobicContact CG2-CB 4.15Å; I73-L85 HydrophobicContact CG2-CD2 3.71Å; I73-Q88 HydrophobicContact CB-CB 4.2Å; I73-Q88 HydrophobicContact CG2-CB 3.53Å; I73-Q88 HydrophobicContact CG2-CG 4.33Å; I73-Q88 PolarHBondContact N-O 3.24Å; I73-V90 HydrophobicContact CB-CG2 4.24Å; I73-T128 HydrophobicContact CB-CG2 4.04Å; I73-T128 HydrophobicContact CD1-CG2 3.98Å; I73-T128 HydrophobicContact CG1-CG2 4.29Å; I73-M132 HydrophobicContact CD1-CB 4.43Å; I73-M132 HydrophobicContact CD1-CE 3.7Å; I73-M132 HydrophobicContact CD1-SD 3.56Å; I73-M132 VanDerWaalsContact CD1-SD 3.56Å; I73-Y142 HydrophobicContact CD1-CE2 3.98Å; I73-Y142 WeakPolarHBondContact CD1-OH 3.41Å; I73-Y142 HydrophobicContact CG1-CE1 4.17Å; I73-Y142 HydrophobicContact CG1-CE2 4.48Å; I73-Y142 VanDerWaalsContact CG1-OH 3.23Å; I73-Y142 WeakPolarHBondContact CG1-OH 3.38Å
74V94.2Very high93.9Very high40 Ų4022.7 Ų22.724%0.24212%0.121CC..  trans-131.5115.2-179.7-178.80000110.4
75F92.4Very high93.7Very high60 Ų6022.7 Ų22.726%0.26312%0.121SC..  trans-161.1165.2168.159.5-86.8000110.9I73 V77 W84 L85 M132I73-F75 HydrophobicContact CD1-CD1 4.03Å; I73-F75 HydrophobicContact CD1-CE1 3.69Å; I73-F75 HydrophobicContact CG1-CD1 3.87Å; I73-F75 HydrophobicContact CG1-CE1 3.91Å; I73-F75 HydrophobicContact CG2-CD1 4.26Å; I73-F75 HydrophobicContact CG2-CE1 3.82Å; F75-V77 HydrophobicContact CD2-CG2 3.9Å; F75-V77 HydrophobicContact CE2-CG2 3.58Å; F75-W84 HydrophobicContact CE1-CZ3 4.46Å; F75-W84 AromaticContact CE2-CH2 3.89Å; F75-W84 HydrophobicContact CE2-CH2 3.89Å; F75-W84 AromaticContact CZ-CH2 3.51Å; F75-W84 HydrophobicContact CZ-CH2 3.51Å; F75-W84 AromaticContact CZ-CZ3 3.81Å; F75-W84 HydrophobicContact CZ-CZ3 3.81Å; F75-L85 HydrophobicContact CD1-CD2 3.69Å; F75-L85 HydrophobicContact CD2-CD2 4.33Å; F75-L85 HydrophobicContact CE1-CD2 3.2Å; F75-L85 HydrophobicContact CE2-CD2 3.93Å; F75-L85 HydrophobicContact CG-CD2 4.25Å; F75-L85 HydrophobicContact CZ-CD2 3.36Å; F75-L85 VanDerWaalsContact O-CD1 3.3Å; F75-L85 WeakPolarHBondContact O-CD1 3.12Å; F75-M132 HydrophobicContact CD1-CE 3.77Å; F75-M132 HydrophobicContact CE1-CE 3.59Å; F75-M132 HydrophobicContact CE1-SD 4.11Å; F75-M132 HydrophobicContact CG-CE 4.36Å; F75-M132 HydrophobicContact CZ-CE 4.04Å; F75-M132 HydrophobicContact CZ-SD 4.39Å
76E90.2Very high93.5Very high78 Ų7822.6 Ų22.636%0.36412%0.12SC..  trans-96.9135.3178.6-67.7174.9-147.700112.6D80 R81 K381 F395E76-D80 CarbonylContact C-O 3.59Å; E76-D80 VanDerWaalsContact CA-O 3.27Å; E76-D80 WeakPolarHBondContact CA-O 3.28Å; E76-R81 HydrophobicContact CG-CG 4.41Å; E76-K381 PolarHBondContact O-NZ 2.74Å; E76-F395 HydrophobicContact CG-CE2 3.77Å; E76-F395 HydrophobicContact CG-CZ 3.84Å; E76-F395 VanDerWaalsContact OE1-CE2 3.29Å; E76-F395 WeakPolarHBondContact OE1-CE2 3.33Å
77V83.8Confident93.4Very high4 Ų423.3 Ų23.32%0.02412%0.123CC..BIsolated β-bridgetrans-113.8110.8171.8-1770000106.2F75 G79 D80 W84 K381 F383F75-V77 HydrophobicContact CD2-CG2 3.9Å; F75-V77 HydrophobicContact CE2-CG2 3.58Å; V77-G79 VanDerWaalsContact C-N 3.26Å; V77-G79 PolarHBondContact O-N 3.01Å; V77-D80 PolarHBondContact N-O 2.99Å; V77-D80 PolarHBondContact O-N 3.43Å; V77-D80 VanDerWaalsContact O-N 3.12Å; V77-W84 HydrophobicContact CG2-CH2 4.33Å; V77-W84 HydrophobicContact CG2-CZ2 4.05Å; V77-K381 HydrophobicContact CB-CD 4.48Å; V77-K381 HydrophobicContact CG1-CB 3.62Å; V77-K381 HydrophobicContact CG1-CD 3.7Å; V77-K381 HydrophobicContact CG1-CG 3.79Å; V77-F383 HydrophobicContact CG1-CD2 4.36Å; V77-F383 WeakPolarHBondContact O-CD2 3.29Å; V77-F383 VanDerWaalsContact O-CE2 3.26Å; V77-F383 WeakPolarHBondContact O-CE2 3.25Å
78N82.2Confident93.3Very high101 Ų10123.6 Ų23.654%0.5412%0.124SC..THydrogen-bonded Turntrans50.840.4-178.7-55.7-23.1000114.5K381 F383N78-K381 VanDerWaalsContact OD1-CD 3.28Å; N78-K381 WeakPolarHBondContact OD1-CD 3.49Å; N78-F383 HydrophobicContact CB-CD2 3.68Å; N78-F383 HydrophobicContact CB-CE2 4.05Å; N78-F383 HydrophobicContact CB-CG 4.36Å
79G86.5Confident93.3Very high49 Ų4923.6 Ų23.651%0.50512%0.124SC..THydrogen-bonded Turntrans82.58.3177.100000115.2V77 F395V77-G79 VanDerWaalsContact C-N 3.26Å; V77-G79 PolarHBondContact O-N 3.01Å; G79-F395 WeakPolarHBondContact O-CZ 3.49Å
80D89.2Confident93.3Very high22 Ų2223.7 Ų23.712%0.11812%0.124CC..BIsolated β-bridgetrans-129.2163.4173.6-162.913.4000112.3E76 V77 F383 G386E76-D80 CarbonylContact C-O 3.59Å; E76-D80 VanDerWaalsContact CA-O 3.27Å; E76-D80 WeakPolarHBondContact CA-O 3.28Å; V77-D80 PolarHBondContact N-O 2.99Å; V77-D80 PolarHBondContact O-N 3.43Å; V77-D80 VanDerWaalsContact O-N 3.12Å; D80-F383 HydrophobicContact CB-CE2 3.59Å; D80-F383 HydrophobicContact CB-CZ 3.87Å; D80-G386 PolarHBondContact OD2-N 3.5Å
81R91.6Very high93.3Very high58 Ų5823.7 Ų23.722%0.21912%0.124CC..  trans-101.7100169.4-69-170.3-173.3171.72.8110.2E76 L85 G386 P393 F395E76-R81 HydrophobicContact CG-CG 4.41Å; R81-L85 HydrophobicContact CB-CD1 3.92Å; R81-L85 HydrophobicContact CG-CD1 4.44Å; R81-G386 WeakPolarHBondContact O-CA 3.39Å; R81-P393 PolarHBondContact NH2-O 3.06Å; R81-F395 HydrophobicContact CB-CD1 4.19Å; R81-F395 HydrophobicContact CB-CG 4.28Å; R81-F395 HydrophobicContact CG-CB 4.14Å; R81-F395 HydrophobicContact CG-CD1 3.94Å; R81-F395 HydrophobicContact CG-CD2 3.83Å; R81-F395 HydrophobicContact CG-CE1 4.3Å; R81-F395 HydrophobicContact CG-CE2 4.16Å; R81-F395 HydrophobicContact CG-CG 3.69Å; R81-F395 HydrophobicContact CG-CZ 4.38Å; R81-F395 VanDerWaalsContact NE-CD2 3.28Å
82S91.6Very high93.3Very high0 Ų025 Ų250%013%0.13CC..  trans-53.6148.5179.5-610000113.5W84 L85 R97 F384S82-W84 VanDerWaalsContact C-N 3.32Å; S82-W84 VanDerWaalsContact CB-CE2 3.49Å; S82-W84 PolarHBondContact O-N 3.14Å; S82-L85 WeakPolarHBondContact O-CB 3.41Å; S82-L85 WeakPolarHBondContact O-CD1 3.29Å; S82-L85 VanDerWaalsContact O-CG 3.3Å; S82-L85 WeakPolarHBondContact O-CG 3.28Å; S82-L85 PolarHBondContact O-N 3.15Å; S82-R97 PolarHBondContact O-NH1 3.04Å; S82-R97 PolarHBondContact O-NH2 3.21Å; S82-F384 VanDerWaalsContact CA-O 3.25Å; S82-F384 WeakPolarHBondContact CA-O 3.44Å; S82-F384 WeakPolarHBondContact CB-O 3.09Å; S82-F384 PolarHBondContact OG-O 3Å
83W92.8Very high93.3Very high13 Ų1329 Ų295%0.04915%0.147CC..G310 helixtrans-60.3-39.9-179.970.4-92.9000112.8F41 L85 R86 Y87 H319 D320 Y361F41-W83 HydrophobicContact CE1-CB 4.46Å; F41-W83 HydrophobicContact CE1-CE3 4.46Å; F41-W83 HydrophobicContact CE2-CE3 4.25Å; F41-W83 HydrophobicContact CZ-CB 4.28Å; F41-W83 AromaticContact CZ-CD2 3.98Å; F41-W83 HydrophobicContact CZ-CD2 3.98Å; F41-W83 AromaticContact CZ-CE3 3.49Å; F41-W83 HydrophobicContact CZ-CE3 3.49Å; F41-W83 VanDerWaalsContact CZ-CE3 3.49Å; F41-W83 HydrophobicContact CZ-CG 4.35Å; F41-W83 HydrophobicContact CZ-CZ3 4.11Å; W83-L85 PolarHBondContact O-N 3.14Å; W83-L85 VanDerWaalsContact O-N 3.08Å; W83-R86 WeakPolarHBondContact O-CB 3.45Å; W83-R86 PolarHBondContact O-N 2.94Å; W83-Y87 HydrophobicContact CE3-CD2 4.07Å; W83-Y87 HydrophobicContact CE3-CE2 4.05Å; W83-Y87 AromaticContact CZ3-CD2 3.81Å; W83-Y87 HydrophobicContact CZ3-CD2 3.81Å; W83-Y87 AromaticContact CZ3-CE2 3.81Å; W83-Y87 HydrophobicContact CZ3-CE2 3.81Å; W83-H319 AromaticContact CH2-CD2 3.95Å; W83-H319 AromaticContact CZ3-CD2 3.61Å; W83-D320 WeakPolarHBondContact CH2-OD1 3.38Å; W83-Y361 VanDerWaalsContact CB-OH 3.23Å; W83-Y361 WeakPolarHBondContact CB-OH 3.33Å
84W92.7Very high93.4Very high42 Ų4229.1 Ų29.116%0.15915%0.148CC..G310 helixtrans-66.7-14.7-175.454.9-105.1000113.1F75 V77 S82 R86 Y87 Q88 F384F75-W84 HydrophobicContact CE1-CZ3 4.46Å; F75-W84 AromaticContact CE2-CH2 3.89Å; F75-W84 HydrophobicContact CE2-CH2 3.89Å; F75-W84 AromaticContact CZ-CH2 3.51Å; F75-W84 HydrophobicContact CZ-CH2 3.51Å; F75-W84 AromaticContact CZ-CZ3 3.81Å; F75-W84 HydrophobicContact CZ-CZ3 3.81Å; V77-W84 HydrophobicContact CG2-CH2 4.33Å; V77-W84 HydrophobicContact CG2-CZ2 4.05Å; S82-W84 VanDerWaalsContact C-N 3.32Å; S82-W84 VanDerWaalsContact CB-CE2 3.49Å; S82-W84 PolarHBondContact O-N 3.14Å; W84-R86 PolarHBondContact O-N 3.09Å; W84-Y87 PolarHBondContact O-N 2.82Å; W84-Q88 VanDerWaalsContact CE3-NE2 3.32Å; W84-F384 AromaticContact CD1-CD2 3.58Å; W84-F384 AromaticContact NE1-CD2 3.54Å
85L94.4Very high93.6Very high0 Ų031.2 Ų31.20%016%0.155CC..G310 helixtrans-57.1-31.1172.1-62.6169.8000111.1H72 I73 F75 R81 S82 W83 Y87 Q88H72-L85 WeakPolarHBondContact CB-O 3.38Å; I73-L85 HydrophobicContact CG2-CB 4.15Å; I73-L85 HydrophobicContact CG2-CD2 3.71Å; F75-L85 HydrophobicContact CD1-CD2 3.69Å; F75-L85 HydrophobicContact CD2-CD2 4.33Å; F75-L85 HydrophobicContact CE1-CD2 3.2Å; F75-L85 HydrophobicContact CE2-CD2 3.93Å; F75-L85 HydrophobicContact CG-CD2 4.25Å; F75-L85 HydrophobicContact CZ-CD2 3.36Å; F75-L85 VanDerWaalsContact O-CD1 3.3Å; F75-L85 WeakPolarHBondContact O-CD1 3.12Å; R81-L85 HydrophobicContact CB-CD1 3.92Å; R81-L85 HydrophobicContact CG-CD1 4.44Å; S82-L85 WeakPolarHBondContact O-CB 3.41Å; S82-L85 WeakPolarHBondContact O-CD1 3.29Å; S82-L85 VanDerWaalsContact O-CG 3.3Å; S82-L85 WeakPolarHBondContact O-CG 3.28Å; S82-L85 PolarHBondContact O-N 3.15Å; W83-L85 PolarHBondContact O-N 3.14Å; W83-L85 VanDerWaalsContact O-N 3.08Å; L85-Y87 PolarHBondContact O-N 2.98Å; L85-Q88 WeakPolarHBondContact O-CB 3.33Å; L85-Q88 PolarHBondContact O-N 3.22Å; L85-Q88 VanDerWaalsContact O-N 3.14Å
86R94.8Very high93.7Very high0 Ų028.9 Ų28.90%015%0.146CC..G310 helixtrans-61.5-30.9176-179.3176.9-73.5-92.812112.9E42 P68 W83 W84 Q88 S96 S98E42-R86 WeakPolarHBondContact OE1-CD 3.29Å; E42-R86 IonicContact OE1-CZ 3.64Å; E42-R86 IonicContact OE1-NE 2.72Å; E42-R86 PolarHBondContact OE1-NE 2.9Å; P68-R86 HydrophobicContact CB-CG 4.08Å; P68-R86 HydrophobicContact CG-CG 4.22Å; P68-R86 WeakPolarHBondContact O-CD 3.37Å; P68-R86 PolarHBondContact O-NH1 2.03Å; W83-R86 WeakPolarHBondContact O-CB 3.45Å; W83-R86 PolarHBondContact O-N 2.94Å; W84-R86 PolarHBondContact O-N 3.09Å; R86-Q88 PolarHBondContact O-N 3.16Å; R86-S96 PolarHBondContact NH1-OG 3.28Å; R86-S98 VanDerWaalsContact NH2-N 3.15Å; R86-S98 PolarHBondContact NH2-OG 3.31Å
87Y97Very high93.9Very high16 Ų1626.8 Ų26.86%0.06314%0.135CC..G310 helixtrans-85.617179.3-69-101.9000112F41 P68 W83 W84 L85 P89 D121 V123 H126 H319F41-Y87 AromaticContact CE2-CE2 3.95Å; F41-Y87 HydrophobicContact CE2-CE2 3.95Å; P68-Y87 HydrophobicContact CG-CD1 3.88Å; P68-Y87 HydrophobicContact CG-CD2 4.43Å; P68-Y87 HydrophobicContact CG-CE1 3.67Å; P68-Y87 HydrophobicContact CG-CE2 4.23Å; P68-Y87 HydrophobicContact CG-CG 4.25Å; W83-Y87 HydrophobicContact CE3-CD2 4.07Å; W83-Y87 HydrophobicContact CE3-CE2 4.05Å; W83-Y87 AromaticContact CZ3-CD2 3.81Å; W83-Y87 HydrophobicContact CZ3-CD2 3.81Å; W83-Y87 AromaticContact CZ3-CE2 3.81Å; W83-Y87 HydrophobicContact CZ3-CE2 3.81Å; W84-Y87 PolarHBondContact O-N 2.82Å; L85-Y87 PolarHBondContact O-N 2.98Å; Y87-P89 WeakPolarHBondContact O-CD 3.06Å; Y87-D121 WeakPolarHBondContact CE1-OD2 3.5Å; Y87-D121 PolarHBondContact OH-OD2 2.99Å; Y87-V123 HydrophobicContact CD1-CG2 3.74Å; Y87-V123 HydrophobicContact CE1-CG2 4.41Å; Y87-V123 HydrophobicContact CG-CG2 4.4Å; Y87-H126 PolarHBondContact O-NE2 3.45Å; Y87-H319 AromaticContact CE1-NE2 3.84Å; Y87-H319 AromaticContact CZ-NE2 3.4Å; Y87-H319 PolarHBondContact OH-NE2 3.41Å
88Q97.7Very high94.6Very high10 Ų1026.8 Ų26.85%0.04714%0.135CC..SBendtrans-120.783.5176.3-68.8-160.419.900110.2H72 I73 W84 L85 R86 L187H72-Q88 CarbonylContact C-O 3.58Å; H72-Q88 VanDerWaalsContact CA-O 3.28Å; H72-Q88 WeakPolarHBondContact CA-O 3.27Å; I73-Q88 HydrophobicContact CB-CB 4.2Å; I73-Q88 HydrophobicContact CG2-CB 3.53Å; I73-Q88 HydrophobicContact CG2-CG 4.33Å; I73-Q88 PolarHBondContact N-O 3.24Å; W84-Q88 VanDerWaalsContact CE3-NE2 3.32Å; L85-Q88 WeakPolarHBondContact O-CB 3.33Å; L85-Q88 PolarHBondContact O-N 3.22Å; L85-Q88 VanDerWaalsContact O-N 3.14Å; R86-Q88 PolarHBondContact O-N 3.16Å; Q88-L187 HydrophobicContact CG-CD2 3.64Å
89P98.4Very high95.3Very high0 Ų022.6 Ų22.60%012%0.116CC..BIsolated β-bridgetrans-59.8138.5-177.4-25.134.4000113.3N70 E71 Y87 V123 M127 T128N70-P89 WeakPolarHBondContact ND2-CB 3.19Å; E71-P89 WeakPolarHBondContact O-CA 3.32Å; Y87-P89 WeakPolarHBondContact O-CD 3.06Å; P89-V123 HydrophobicContact CG-CB 3.8Å; P89-V123 HydrophobicContact CG-CG1 3.67Å; P89-M127 HydrophobicContact CB-CE 4.02Å; P89-M127 HydrophobicContact CB-SD 3.86Å; P89-M127 CarbonylContact O-C 3.47Å; P89-T128 WeakPolarHBondContact O-CG2 3.5Å; P89-T128 PolarHBondContact O-N 3.08Å
90V98.5Very high95.9Very high1 Ų122.7 Ų22.71%0.00611%0.107CC..SBendtrans-104.5-34.3166.7166.30000110.4E71 I73 T128 Y142 Y151E71-V90 HydrophobicContact CG-CB 4.06Å; E71-V90 HydrophobicContact CG-CG1 4.34Å; E71-V90 PolarHBondContact O-N 2.9Å; I73-V90 HydrophobicContact CB-CG2 4.24Å; V90-T128 HydrophobicContact CG2-CG2 3.52Å; V90-Y142 HydrophobicContact CB-CD1 4.37Å; V90-Y142 HydrophobicContact CG1-CD1 3.82Å; V90-Y142 HydrophobicContact CG1-CG 4.26Å; V90-Y142 HydrophobicContact CG2-CD1 3.61Å; V90-Y142 HydrophobicContact CG2-CE1 3.89Å; V90-Y142 HydrophobicContact CG2-CG 4.12Å; V90-Y151 VanDerWaalsContact O-CD1 3.31Å; V90-Y151 WeakPolarHBondContact O-CD1 3.06Å
91S98.5Very high96.3Very high0 Ų024.7 Ų24.70%012%0.115CC..  trans-156.3-174.9171.784.30000110.6N70 E71 K93N70-S91 WeakPolarHBondContact CB-O 3.11Å; E71-S91 VanDerWaalsContact OE2-CB 3.32Å; E71-S91 WeakPolarHBondContact OE2-CB 3.39Å; E71-S91 PolarHBondContact OE2-OG 3.09Å; S91-K93 WeakPolarHBondContact OG-CB 3.47Å; S91-K93 WeakPolarHBondContact OG-CG 3.41Å; S91-K93 PolarHBondContact OG-N 2.65Å; S91-K93 VanDerWaalsContact OG-N 3.13Å
92Y98.6Very high96.7Very high28 Ų2828.6 Ų28.611%0.1114%0.136CC..SBendtrans-9911.6174.5-60.9-44.6000113.9V154 Y156 K200 V201 Y204Y92-V154 HydrophobicContact CD2-CB 4.21Å; Y92-V154 HydrophobicContact CD2-CG2 3.87Å; Y92-V154 HydrophobicContact CE2-CB 4.47Å; Y92-V154 HydrophobicContact CE2-CG2 3.77Å; Y92-Y156 HydrophobicContact CE2-CE2 4.12Å; Y92-Y156 PolarHBondContact OH-OH 3.38Å; Y92-K200 HydrophobicContact CE2-CB 4.41Å; Y92-V201 WeakPolarHBondContact OH-CG2 3.45Å; Y92-Y204 AromaticContact CD1-CD1 3.58Å; Y92-Y204 HydrophobicContact CD1-CD1 3.58Å; Y92-Y204 HydrophobicContact CD1-CD2 4.07Å; Y92-Y204 AromaticContact CD1-CE1 3.97Å; Y92-Y204 HydrophobicContact CD1-CE1 3.97Å; Y92-Y204 HydrophobicContact CD1-CE2 4.4Å; Y92-Y204 AromaticContact CD1-CG 3.62Å; Y92-Y204 HydrophobicContact CD1-CG 3.62Å; Y92-Y204 HydrophobicContact CD2-CG 4.25Å; Y92-Y204 AromaticContact CE1-CD1 3.91Å; Y92-Y204 HydrophobicContact CE1-CD1 3.91Å; Y92-Y204 HydrophobicContact CE1-CE1 4.34Å; Y92-Y204 HydrophobicContact CE1-CG 4.31Å; Y92-Y204 HydrophobicContact CG-CD1 4.06Å; Y92-Y204 AromaticContact CG-CD2 3.98Å; Y92-Y204 HydrophobicContact CG-CD2 3.98Å; Y92-Y204 AromaticContact CG-CG 3.61Å; Y92-Y204 HydrophobicContact CG-CG 3.61Å
93K98.5Very high97Very high87 Ų8731.2 Ų31.238%0.37815%0.148SC..  trans-60.7141.9168-71.8177.2175.4171.80110N70 E71 S91 E95 G138 S140 A153N70-K93 CarbonylContact C-O 3.51Å; N70-K93 WeakPolarHBondContact CA-O 3.49Å; E71-K93 HydrophobicContact CB-CB 4.2Å; E71-K93 PolarHBondContact N-O 3.35Å; S91-K93 WeakPolarHBondContact OG-CB 3.47Å; S91-K93 WeakPolarHBondContact OG-CG 3.41Å; S91-K93 PolarHBondContact OG-N 2.65Å; S91-K93 VanDerWaalsContact OG-N 3.13Å; K93-E95 VanDerWaalsContact C-N 3.26Å; K93-E95 PolarHBondContact O-N 3.18Å; K93-E95 VanDerWaalsContact O-N 3.08Å; K93-G138 PolarHBondContact NZ-O 3.29Å; K93-S140 WeakPolarHBondContact CE-OG 3.41Å; K93-S140 PolarHBondContact NZ-OG 3.03Å; K93-A153 HydrophobicContact CD-CB 4.46Å
94L98.6Very high97.3Very high3 Ų330.6 Ų30.62%0.01615%0.146CC..SBendtrans-88.962178.6-53.6-175.5000111.2P69 T100 E101 F104 Y204 L208 L211P69-L94 HydrophobicContact CB-CD2 4.18Å; P69-L94 HydrophobicContact CG-CD2 4.08Å; L94-T100 CarbonylContact O-C 3.48Å; L94-E101 HydrophobicContact CB-CB 3.92Å; L94-E101 HydrophobicContact CB-CG 4.06Å; L94-E101 HydrophobicContact CD1-CG 3.99Å; L94-E101 HydrophobicContact CG-CG 4.45Å; L94-E101 PolarHBondContact O-N 2.84Å; L94-F104 HydrophobicContact CD1-CD1 3.84Å; L94-F104 HydrophobicContact CD1-CE1 4.17Å; L94-Y204 HydrophobicContact CD2-CE2 3.82Å; L94-L208 HydrophobicContact CD1-CD2 3.79Å; L94-L208 HydrophobicContact CD2-CD2 3.83Å; L94-L211 HydrophobicContact CD1-CD1 3.46Å; L94-L211 VanDerWaalsContact CD1-CD1 3.46Å
95E97.1Very high97.6Very high83 Ų8331 Ų3139%0.38815%0.153SC..  trans-132103.2179.5-169.8172.8172.800109.6E71 K93 S137 G138E71-E95 WeakPolarHBondContact CA-O 3.34Å; K93-E95 VanDerWaalsContact C-N 3.26Å; K93-E95 PolarHBondContact O-N 3.18Å; K93-E95 VanDerWaalsContact O-N 3.08Å; E95-S137 PolarHBondContact O-OG 2.77Å; E95-G138 WeakPolarHBondContact OE2-CA 3.38Å
96S95.9Very high97.8Very high11 Ų1134 Ų348%0.07717%0.169CC..BIsolated β-bridgetrans-135.8175.8-171.775.80000110.9W45 R86 S98 G99W45-S96 WeakPolarHBondContact CZ2-OG 3.46Å; R86-S96 PolarHBondContact NH1-OG 3.28Å; S96-S98 PolarHBondContact O-N 2.95Å; S96-S98 PolarHBondContact OG-N 3.16Å; S96-G99 PolarHBondContact N-O 3.22Å; S96-G99 PolarHBondContact O-N 2.72Å; S96-G99 VanDerWaalsContact O-O 3.09Å
97R94.5Very high98Very high35 Ų3534 Ų3413%0.13217%0.169CC..THydrogen-bonded Turntrans-61.6-5.9172.571.7178.170.6-173.7-9.4114.6E42 H72 S82 P387 T397E42-R97 VanDerWaalsContact OE2-CD 3.23Å; E42-R97 WeakPolarHBondContact OE2-CD 2.95Å; E42-R97 IonicContact OE2-CZ 3.62Å; E42-R97 IonicContact OE2-NE 3.65Å; E42-R97 IonicContact OE2-NH1 2.92Å; E42-R97 PolarHBondContact OE2-NH1 3.49Å; H72-R97 PolarHBondContact NE2-N 3.04Å; S82-R97 PolarHBondContact O-NH1 3.04Å; S82-R97 PolarHBondContact O-NH2 3.21Å; R97-P387 VanDerWaalsContact NH1-CD 3.32Å; R97-T397 PolarHBondContact O-OG1 2.72Å
98S97.6Very high98.1Very high3 Ų333.3 Ų33.32%0.02117%0.166CC..THydrogen-bonded Turntrans-87.5-18172.5-71.20000113.5W43 R44 W45 R86 S96W43-S98 WeakPolarHBondContact O-CB 3.41Å; W43-S98 PolarHBondContact O-OG 3.13Å; R44-S98 WeakPolarHBondContact CA-O 3.04Å; R44-S98 WeakPolarHBondContact CB-O 3.33Å; W45-S98 VanDerWaalsContact CE2-CB 3.48Å; W45-S98 PolarHBondContact N-O 3.18Å; R86-S98 VanDerWaalsContact NH2-N 3.15Å; R86-S98 PolarHBondContact NH2-OG 3.31Å; S96-S98 PolarHBondContact O-N 2.95Å; S96-S98 PolarHBondContact OG-N 3.16Å
99G97.6Very high98.2Very high14 Ų1438 Ų3814%0.14419%0.187CC..BIsolated β-bridgetrans145.3-165.5-17700000115.4W45 S96 E103W45-G99 VanDerWaalsContact CE3-C 3.48Å; W45-G99 WeakPolarHBondContact CZ3-O 2.98Å; S96-G99 PolarHBondContact N-O 3.22Å; S96-G99 PolarHBondContact O-N 2.72Å; S96-G99 VanDerWaalsContact O-O 3.09Å; G99-E103 VanDerWaalsContact C-OE2 3.3Å; G99-E103 WeakPolarHBondContact CA-OE2 3.41Å
100T98.1Very high98.2Very high51 Ų5140.7 Ų40.731%0.31320%0.197SC..  trans-9916517477.70000112.9W45 L94 E102 E103 F104W45-T100 VanDerWaalsContact CZ3-C 3.42Å; W45-T100 WeakPolarHBondContact CZ3-O 3.41Å; L94-T100 CarbonylContact O-C 3.48Å; T100-E102 VanDerWaalsContact CB-OE2 3.25Å; T100-E102 WeakPolarHBondContact CB-OE2 3.3Å; T100-E102 PolarHBondContact O-N 3.07Å; T100-E102 PolarHBondContact OG1-N 3Å; T100-E102 PolarHBondContact OG1-OE2 2.91Å; T100-E103 PolarHBondContact N-OE2 2.73Å; T100-E103 PolarHBondContact O-N 2.78Å; T100-F104 PolarHBondContact O-N 2.76Å
101E98.7Very high98.2Very high64 Ų6440.6 Ų40.630%0.29920%0.196SC..Hα-helixtrans-56.3-34.5179.8-175.9162.2158.400112.8L94 F104 T105 H207 L211L94-E101 HydrophobicContact CB-CB 3.92Å; L94-E101 HydrophobicContact CB-CG 4.06Å; L94-E101 HydrophobicContact CD1-CG 3.99Å; L94-E101 HydrophobicContact CG-CG 4.45Å; L94-E101 PolarHBondContact O-N 2.84Å; E101-F104 PolarHBondContact O-N 3.03Å; E101-T105 WeakPolarHBondContact O-CB 3.46Å; E101-T105 PolarHBondContact O-N 2.77Å; E101-T105 PolarHBondContact O-OG1 2.76Å; E101-H207 IonicContact OE1-CE1 3.88Å; E101-H207 PolarHBondContact OE1-CE1 3.25Å; E101-H207 IonicContact OE1-NE2 2.88Å; E101-H207 PolarHBondContact OE1-NE2 2.03Å; E101-H207 IonicContact OE2-NE2 3.92Å; E101-L211 HydrophobicContact CG-CD1 4.4Å
102E98.8Very high98.2Very high139 Ų13941.7 Ų41.765%0.6520%0.201SC*.Hα-helixtrans-63.1-45.2175.1-61.183.2-177.400111.8T100 F104 T105 D106T100-E102 VanDerWaalsContact CB-OE2 3.25Å; T100-E102 WeakPolarHBondContact CB-OE2 3.3Å; T100-E102 PolarHBondContact O-N 3.07Å; T100-E102 PolarHBondContact OG1-N 3Å; T100-E102 PolarHBondContact OG1-OE2 2.91Å; E102-F104 VanDerWaalsContact C-N 3.34Å; E102-T105 PolarHBondContact O-N 2.71Å; E102-D106 WeakPolarHBondContact O-CB 3.37Å; E102-D106 PolarHBondContact O-N 2.87Å
103E98.8Very high98.2Very high56 Ų5646.5 Ų46.526%0.26223%0.225SC..Hα-helixtrans-65.9-37.3176.5-64.617014600111.1W45 G99 T100 M107W45-E103 HydrophobicContact CB-CB 4.35Å; W45-E103 HydrophobicContact CE3-CB 4.19Å; G99-E103 VanDerWaalsContact C-OE2 3.3Å; G99-E103 WeakPolarHBondContact CA-OE2 3.41Å; T100-E103 PolarHBondContact N-OE2 2.73Å; T100-E103 PolarHBondContact O-N 2.78Å; E103-M107 WeakPolarHBondContact O-CB 3.21Å; E103-M107 PolarHBondContact O-N 3.18Å
104F98.9Very high98.2Very high0 Ų044 Ų440%022%0.217CC..Hα-helixtrans-63-45.2173.7-172.2-116.6000112.1W45 V66 P69 L94 T100 E101 E102 M107 I108 V120 L208 L211 V213W45-F104 AromaticContact CD1-CD2 3.79Å; W45-F104 HydrophobicContact CD2-CB 3.71Å; W45-F104 AromaticContact CD2-CD2 3.71Å; W45-F104 HydrophobicContact CD2-CD2 3.71Å; W45-F104 HydrophobicContact CD2-CG 4.17Å; W45-F104 AromaticContact CE2-CD2 3.38Å; W45-F104 HydrophobicContact CE3-CB 3.51Å; W45-F104 HydrophobicContact CE3-CD2 4.36Å; W45-F104 HydrophobicContact CE3-CG 4.38Å; W45-F104 HydrophobicContact CG-CB 4.34Å; W45-F104 AromaticContact CG-CD2 3.95Å; W45-F104 HydrophobicContact CG-CD2 3.95Å; W45-F104 HydrophobicContact CH2-CB 4.02Å; W45-F104 HydrophobicContact CH2-CD2 4.37Å; W45-F104 HydrophobicContact CH2-CG 4.37Å; W45-F104 HydrophobicContact CZ2-CB 4.24Å; W45-F104 AromaticContact CZ2-CD2 3.76Å; W45-F104 HydrophobicContact CZ2-CD2 3.76Å; W45-F104 HydrophobicContact CZ2-CE2 4.45Å; W45-F104 HydrophobicContact CZ2-CG 4.2Å; W45-F104 HydrophobicContact CZ3-CB 3.66Å; W45-F104 HydrophobicContact CZ3-CG 4.46Å; W45-F104 AromaticContact NE1-CD2 3.47Å; W45-F104 AromaticContact NE1-CE2 3.95Å; V66-F104 HydrophobicContact CG2-CE2 4.25Å; P69-F104 HydrophobicContact CB-CD2 4.44Å; P69-F104 HydrophobicContact CB-CE2 4.12Å; P69-F104 HydrophobicContact CB-CZ 4.26Å; P69-F104 HydrophobicContact CG-CZ 4.39Å; L94-F104 HydrophobicContact CD1-CD1 3.84Å; L94-F104 HydrophobicContact CD1-CE1 4.17Å; T100-F104 PolarHBondContact O-N 2.76Å; E101-F104 PolarHBondContact O-N 3.03Å; E102-F104 VanDerWaalsContact C-N 3.34Å; F104-M107 HydrophobicContact CD2-CE 3.52Å; F104-M107 HydrophobicContact CE2-CE 3.51Å; F104-M107 HydrophobicContact CZ-CE 4.49Å; F104-M107 PolarHBondContact O-N 3.01Å; F104-I108 HydrophobicContact CD1-CD1 3.71Å; F104-I108 HydrophobicContact CE1-CD1 3.36Å; F104-I108 HydrophobicContact CE1-CG1 4.4Å; F104-I108 HydrophobicContact CE2-CD1 4.38Å; F104-I108 HydrophobicContact CG-CD1 4.37Å; F104-I108 HydrophobicContact CZ-CD1 3.74Å; F104-I108 HydrophobicContact CZ-CG1 4.4Å; F104-I108 WeakPolarHBondContact O-CG1 3.41Å; F104-I108 PolarHBondContact O-N 3.4Å; F104-V120 HydrophobicContact CE2-CG2 4.5Å; F104-V120 HydrophobicContact CZ-CG2 3.79Å; F104-L208 HydrophobicContact CD1-CD2 4.46Å; F104-L208 HydrophobicContact CE1-CD2 3.5Å; F104-L208 VanDerWaalsContact CE1-CD2 3.5Å; F104-L208 HydrophobicContact CZ-CD2 4.01Å; F104-L211 HydrophobicContact CD1-CD1 4Å; F104-L211 HydrophobicContact CE1-CD1 4.3Å; F104-V213 HydrophobicContact CE1-CG2 4.05Å; F104-V213 HydrophobicContact CZ-CG2 3.92Å
105T98.9Very high98.2Very high50 Ų5044.9 Ų44.931%0.30723%0.227SC..Hα-helixtrans-65.7-42.4179.7-57.10000111.1E101 E102 I108 K109 L211E101-T105 WeakPolarHBondContact O-CB 3.46Å; E101-T105 PolarHBondContact O-N 2.77Å; E101-T105 PolarHBondContact O-OG1 2.76Å; E102-T105 PolarHBondContact O-N 2.71Å; T105-I108 PolarHBondContact O-N 2.9Å; T105-K109 PolarHBondContact O-N 2.77Å; T105-K109 VanDerWaalsContact O-N 3.1Å; T105-L211 HydrophobicContact CG2-CD2 4.21Å
106D98.9Very high98.3Very high64 Ų6441 Ų4134%0.34221%0.209SC..Hα-helixtrans-60.4-45.6174.4-174.465.6000111.5E102 I108 K109 R110E102-D106 WeakPolarHBondContact O-CB 3.37Å; E102-D106 PolarHBondContact O-N 2.87Å; D106-I108 PolarHBondContact O-N 2.84Å; D106-K109 PolarHBondContact O-N 2.83Å; D106-R110 WeakPolarHBondContact O-CB 3.42Å; D106-R110 WeakPolarHBondContact O-CG 3.42Å; D106-R110 PolarHBondContact O-N 2.84Å; D106-R110 WeakPolarHBondContact OD2-CD 3.38Å; D106-R110 IonicContact OD2-CZ 2.8Å; D106-R110 IonicContact OD2-NE 2.65Å; D106-R110 IonicContact OD2-NH1 3.31Å; D106-R110 PolarHBondContact OD2-NH1 3.29Å
107M98.9Very high98.4Very high0 Ų041.7 Ų41.70%021%0.21CC..Hα-helixtrans-58.7-47177.4177.5-81.2-64.400112.5W45 I48 A49 V66 E103 F104 K109 R110 C111 I118W45-M107 HydrophobicContact CB-CB 3.94Å; W45-M107 HydrophobicContact CB-CG 4.28Å; W45-M107 HydrophobicContact CG-CE 4.42Å; W45-M107 WeakPolarHBondContact O-CB 3.39Å; W45-M107 WeakPolarHBondContact O-CG 3.42Å; I48-M107 HydrophobicContact CB-CG 3.83Å; I48-M107 HydrophobicContact CB-SD 4.39Å; I48-M107 HydrophobicContact CG2-CG 3.66Å; I48-M107 HydrophobicContact CG2-SD 3.65Å; A49-M107 HydrophobicContact CB-CB 4.04Å; A49-M107 HydrophobicContact CB-CG 4.09Å; V66-M107 HydrophobicContact CG1-CE 4.24Å; E103-M107 WeakPolarHBondContact O-CB 3.21Å; E103-M107 PolarHBondContact O-N 3.18Å; F104-M107 HydrophobicContact CD2-CE 3.52Å; F104-M107 HydrophobicContact CE2-CE 3.51Å; F104-M107 HydrophobicContact CZ-CE 4.49Å; F104-M107 PolarHBondContact O-N 3.01Å; M107-K109 VanDerWaalsContact C-N 3.34Å; M107-K109 PolarHBondContact O-N 2.94Å; M107-R110 PolarHBondContact O-N 3.21Å; M107-C111 WeakPolarHBondContact O-CB 3.15Å; M107-C111 PolarHBondContact O-N 2.79Å; M107-C111 PolarHBondContact O-SG 3.24Å; M107-I118 HydrophobicContact CE-CD1 4.32Å; M107-I118 HydrophobicContact CE-CG1 4.25Å; M107-I118 HydrophobicContact CE-CG2 4.14Å; M107-I118 HydrophobicContact SD-CD1 3.39Å; M107-I118 WeakPolarHBondContact SD-CD1 3.39Å; M107-I118 HydrophobicContact SD-CG1 3.66Å
108I98.9Very high98.6Very high0 Ų040 Ų400%020%0.204CC..Hα-helixtrans-58.3-49177-70.8163.8000110.4F104 T105 D106 C111 H112 I118 L211 V213F104-I108 HydrophobicContact CD1-CD1 3.71Å; F104-I108 HydrophobicContact CE1-CD1 3.36Å; F104-I108 HydrophobicContact CE1-CG1 4.4Å; F104-I108 HydrophobicContact CE2-CD1 4.38Å; F104-I108 HydrophobicContact CG-CD1 4.37Å; F104-I108 HydrophobicContact CZ-CD1 3.74Å; F104-I108 HydrophobicContact CZ-CG1 4.4Å; F104-I108 WeakPolarHBondContact O-CG1 3.41Å; F104-I108 PolarHBondContact O-N 3.4Å; T105-I108 PolarHBondContact O-N 2.9Å; D106-I108 PolarHBondContact O-N 2.84Å; I108-C111 PolarHBondContact O-N 3.02Å; I108-H112 WeakPolarHBondContact O-CB 3.29Å; I108-H112 PolarHBondContact O-CD2 2.83Å; I108-H112 VanDerWaalsContact O-CD2 3.25Å; I108-H112 PolarHBondContact O-N 2.83Å; I108-I118 HydrophobicContact CG1-CB 4.28Å; I108-I118 HydrophobicContact CG1-CG1 3.99Å; I108-I118 HydrophobicContact CG1-CG2 4.39Å; I108-L211 HydrophobicContact CD1-CB 3.99Å; I108-L211 VanDerWaalsContact CG2-O 3.28Å; I108-L211 WeakPolarHBondContact CG2-O 3.49Å; I108-V213 HydrophobicContact CD1-CG2 3.72Å
109K98.9Very high98.7Very high110 Ų11040 Ų4048%0.47820%0.203SC..Hα-helixtrans-59.9-50.4-178.3-177.1-173.2171.5-163.50111.5T105 D106 M107 H112 E113T105-K109 PolarHBondContact O-N 2.77Å; T105-K109 VanDerWaalsContact O-N 3.1Å; D106-K109 PolarHBondContact O-N 2.83Å; M107-K109 VanDerWaalsContact C-N 3.34Å; M107-K109 PolarHBondContact O-N 2.94Å; K109-H112 WeakPolarHBondContact O-CB 3.41Å; K109-H112 PolarHBondContact O-N 2.62Å; K109-E113 VanDerWaalsContact CE-OE1 3.28Å; K109-E113 WeakPolarHBondContact CE-OE1 3.2Å; K109-E113 WeakPolarHBondContact O-CG 3.37Å; K109-E113 PolarHBondContact O-N 2.81Å
110R98.9Very high98.8Very high55 Ų5539.3 Ų39.321%0.20820%0.197CC..Hα-helixtrans-66.4-39-177.9-72.7168.365.1-163.5-4.4112.6A49 E53 D106 M107 H112 E113A49-R110 HydrophobicContact CB-CB 4.29Å; E53-R110 WeakPolarHBondContact OE1-CB 3.21Å; E53-R110 IonicContact OE1-CZ 3.83Å; E53-R110 IonicContact OE1-NE 3.39Å; E53-R110 PolarHBondContact OE1-NE 3.24Å; E53-R110 IonicContact OE1-NH2 2.93Å; E53-R110 PolarHBondContact OE1-NH2 3.08Å; E53-R110 IonicContact OE2-CZ 2.72Å; E53-R110 IonicContact OE2-NE 3.46Å; E53-R110 IonicContact OE2-NH2 3.28Å; E53-R110 PolarHBondContact OE2-NH2 3.47Å; D106-R110 WeakPolarHBondContact O-CB 3.42Å; D106-R110 WeakPolarHBondContact O-CG 3.42Å; D106-R110 PolarHBondContact O-N 2.84Å; D106-R110 WeakPolarHBondContact OD2-CD 3.38Å; D106-R110 IonicContact OD2-CZ 2.8Å; D106-R110 IonicContact OD2-NE 2.65Å; D106-R110 IonicContact OD2-NH1 3.31Å; D106-R110 PolarHBondContact OD2-NH1 3.29Å; M107-R110 PolarHBondContact O-N 3.21Å; R110-H112 VanDerWaalsContact C-N 3.34Å; R110-H112 PolarHBondContact O-N 2.88Å; R110-E113 PolarHBondContact O-N 3.08Å
111C98.9Very high98.8Very high0 Ų036.9 Ų36.90%018%0.182CC..Hα-helixtrans-62.9-41172.4-70.40000111.7C52 M107 I108 E113 V114 G115 I116 I118C52-C111 HydrophobicContact CB-CB 3.85Å; C52-C111 WeakPolarHBondContact CB-SG 3.35Å; C52-C111 WeakPolarHBondContact SG-CB 3.33Å; C52-C111 CovalentContact SG-SG 2.05Å; C52-C111 PolarHBondContact SG-SG 2.87Å; M107-C111 WeakPolarHBondContact O-CB 3.15Å; M107-C111 PolarHBondContact O-N 2.79Å; M107-C111 PolarHBondContact O-SG 3.24Å; I108-C111 PolarHBondContact O-N 3.02Å; C111-E113 PolarHBondContact O-N 2.95Å; C111-V114 CarbonylContact O-C 3.58Å; C111-V114 VanDerWaalsContact O-CG2 3.3Å; C111-V114 WeakPolarHBondContact O-CG2 3.49Å; C111-V114 PolarHBondContact O-N 2.93Å; C111-G115 PolarHBondContact O-N 2.79Å; C111-I116 CarbonylContact C-O 3.56Å; C111-I116 HydrophobicContact CB-CB 4.08Å; C111-I116 HydrophobicContact CB-CG2 4.33Å; C111-I116 PolarHBondContact O-N 3.12Å; C111-I118 HydrophobicContact CB-CD1 3.98Å; C111-I118 HydrophobicContact CB-CG1 4.4Å
112H98.6Very high98.8Very high22 Ų2233.8 Ų33.810%0.10217%0.167CC..Hα-helixtrans-62.2-39.5175.1-90-65.2000113.4I108 K109 R110 V114 G115 I116 K117 G212 F243 F244I108-H112 WeakPolarHBondContact O-CB 3.29Å; I108-H112 PolarHBondContact O-CD2 2.83Å; I108-H112 VanDerWaalsContact O-CD2 3.25Å; I108-H112 PolarHBondContact O-N 2.83Å; K109-H112 WeakPolarHBondContact O-CB 3.41Å; K109-H112 PolarHBondContact O-N 2.62Å; R110-H112 VanDerWaalsContact C-N 3.34Å; R110-H112 PolarHBondContact O-N 2.88Å; H112-V114 PolarHBondContact O-N 3.37Å; H112-V114 VanDerWaalsContact O-N 3.13Å; H112-G115 PolarHBondContact O-N 2.87Å; H112-I116 PolarHBondContact N-O 2.89Å; H112-K117 WeakPolarHBondContact CE1-CD 3.21Å; H112-G212 PolarHBondContact NE2-O 2.96Å; H112-F243 HydrophobicContact CB-CD1 3.88Å; H112-F243 HydrophobicContact CB-CE1 4.36Å; H112-F243 AromaticContact CD2-CD1 3.32Å; H112-F243 WeakPolarHBondContact CD2-CD1 3.25Å; H112-F243 AromaticContact CD2-CE1 3.91Å; H112-F243 AromaticContact CD2-CG 3.76Å; H112-F243 AromaticContact CG-CD1 3.59Å; H112-F243 AromaticContact NE2-CD1 3.86Å; H112-F243 AromaticContact NE2-CG 3.8Å; H112-F244 AromaticContact CE1-CE1 3.96Å; H112-F244 AromaticContact CE1-CE2 3.69Å; H112-F244 AromaticContact CE1-CZ 3.37Å; H112-F244 WeakPolarHBondContact CE1-CZ 3.27Å; H112-F244 AromaticContact NE2-CE2 3.82Å; H112-F244 AromaticContact NE2-CZ 3.77Å
113E98.7Very high98.8Very high129 Ų12927.2 Ų27.260%0.60314%0.137SC*.Hα-helixtrans-57.3-26.8177.8-74.1176.5-17300112.7K109 R110 C111K109-E113 VanDerWaalsContact CE-OE1 3.28Å; K109-E113 WeakPolarHBondContact CE-OE1 3.2Å; K109-E113 WeakPolarHBondContact O-CG 3.37Å; K109-E113 PolarHBondContact O-N 2.81Å; R110-E113 PolarHBondContact O-N 3.08Å; C111-E113 PolarHBondContact O-N 2.95Å
114V98.6Very high98.8Very high34 Ų3424.6 Ų24.621%0.20612%0.124CC..THydrogen-bonded Turntrans-108.515.9177.1-58.10000113.5C52 E53 Q57 C111 H112 I116C52-V114 HydrophobicContact CB-CG2 3.95Å; E53-V114 HydrophobicContact CG-CG1 4.32Å; Q57-V114 HydrophobicContact CB-CB 3.89Å; Q57-V114 HydrophobicContact CB-CG2 4.23Å; C111-V114 CarbonylContact O-C 3.58Å; C111-V114 VanDerWaalsContact O-CG2 3.3Å; C111-V114 WeakPolarHBondContact O-CG2 3.49Å; C111-V114 PolarHBondContact O-N 2.93Å; H112-V114 PolarHBondContact O-N 3.37Å; H112-V114 VanDerWaalsContact O-N 3.13Å; V114-I116 HydrophobicContact CG2-CG1 4.08Å; V114-I116 PolarHBondContact O-N 3.14Å
115G98.1Very high98.8Very high23 Ų2324.7 Ų24.724%0.23713%0.125CC..THydrogen-bonded Turntrans85.4-3.9173.500000115.8C111 H112 K117C111-G115 PolarHBondContact O-N 2.79Å; H112-G115 PolarHBondContact O-N 2.87Å; G115-K117 PolarHBondContact O-NZ 3.25Å
116I98.9Very high98.8Very high0 Ų022.5 Ų22.50%011%0.111CC..PPolyproline II helixtrans-83.3134.9-177.4-55.9-62.5000111.3C52 L56 I61 G62 V64 C111 H112 V114C52-I116 HydrophobicContact CB-CB 4.46Å; C52-I116 HydrophobicContact CB-CG1 4.37Å; L56-I116 HydrophobicContact CB-CD1 3.98Å; L56-I116 HydrophobicContact CB-CG1 4.19Å; I61-I116 WeakPolarHBondContact O-CD1 3.41Å; G62-I116 CarbonylContact O-C 3.54Å; G62-I116 WeakPolarHBondContact O-CA 3.3Å; V64-I116 HydrophobicContact CG2-CG2 3.76Å; C111-I116 CarbonylContact C-O 3.56Å; C111-I116 HydrophobicContact CB-CB 4.08Å; C111-I116 HydrophobicContact CB-CG2 4.33Å; C111-I116 PolarHBondContact O-N 3.12Å; H112-I116 PolarHBondContact N-O 2.89Å; V114-I116 HydrophobicContact CG2-CG1 4.08Å; V114-I116 PolarHBondContact O-N 3.14Å
117K98.9Very high98.7Very high26 Ų2619.4 Ų19.411%0.11310%0.095CC..EExtended strand (participates in β ladder)trans-103145.5-177.6-57.5-59.7174.2-92.20111.7Q29 V30 G62 A63 V64 H112 G115 A214 F244Q29-K117 WeakPolarHBondContact O-CG 3.48Å; V30-K117 HydrophobicContact CG1-CB 4.09Å; V30-K117 HydrophobicContact CG1-CG 3.59Å; G62-K117 PolarHBondContact O-N 2.95Å; A63-K117 CarbonylContact C-O 3.52Å; A63-K117 WeakPolarHBondContact CA-O 3.15Å; A63-K117 HydrophobicContact CB-CB 4.15Å; V64-K117 PolarHBondContact N-O 3.23Å; H112-K117 WeakPolarHBondContact CE1-CD 3.21Å; G115-K117 PolarHBondContact O-NZ 3.25Å; K117-A214 HydrophobicContact CB-CB 3.78Å; K117-A214 HydrophobicContact CG-CB 4.46Å; K117-F244 HydrophobicContact CD-CE1 3.72Å; K117-F244 HydrophobicContact CD-CZ 4.08Å
118I98.9Very high98.7Very high0 Ų019.4 Ų19.40%010%0.095CC..EExtended strand (participates in β ladder)trans-103.1127.3-179.9-57.3-52.3000110.1V64 V66 M107 I108 C111 V213 A214V64-I118 HydrophobicContact CB-CD1 3.97Å; V66-I118 HydrophobicContact CG1-CG2 4.07Å; V66-I118 HydrophobicContact CG2-CG2 4.21Å; M107-I118 HydrophobicContact CE-CD1 4.32Å; M107-I118 HydrophobicContact CE-CG1 4.25Å; M107-I118 HydrophobicContact CE-CG2 4.14Å; M107-I118 HydrophobicContact SD-CD1 3.39Å; M107-I118 WeakPolarHBondContact SD-CD1 3.39Å; M107-I118 HydrophobicContact SD-CG1 3.66Å; I108-I118 HydrophobicContact CG1-CB 4.28Å; I108-I118 HydrophobicContact CG1-CG1 3.99Å; I108-I118 HydrophobicContact CG1-CG2 4.39Å; C111-I118 HydrophobicContact CB-CD1 3.98Å; C111-I118 HydrophobicContact CB-CG1 4.4Å; I118-V213 HydrophobicContact CG2-CG2 4.49Å; I118-A214 WeakPolarHBondContact O-CB 3.47Å; I118-A214 PolarHBondContact O-N 3.4Å
119I98.9Very high98.5Very high2 Ų220 Ų201%0.0110%0.1CC..EExtended strand (participates in β ladder)trans-112.8126.8172.5-59.9167000107.2L28 V37 A63 V64 Q65 V66 G215 F251L28-I119 HydrophobicContact CD1-CD1 3.56Å; V37-I119 HydrophobicContact CG1-CD1 4.19Å; V37-I119 HydrophobicContact CG2-CD1 4.4Å; A63-I119 HydrophobicContact CB-CD1 3.86Å; A63-I119 HydrophobicContact CB-CG1 4.39Å; V64-I119 PolarHBondContact O-N 2.92Å; Q65-I119 CarbonylContact C-O 3.52Å; Q65-I119 VanDerWaalsContact CA-O 3.28Å; Q65-I119 WeakPolarHBondContact CA-O 3.24Å; V66-I119 PolarHBondContact N-O 3.44Å; I119-G215 WeakPolarHBondContact CA-O 3.41Å; I119-F251 HydrophobicContact CD1-CD1 3.87Å; I119-F251 HydrophobicContact CD1-CE1 4.16Å; I119-F251 HydrophobicContact CG1-CD1 4.37Å
120V98.9Very high98.3Very high0 Ų015.4 Ų15.40%08%0.082CC..EExtended strand (participates in β ladder)trans-94.3132.3-179.8164.30000110.6V66 P69 F104 A122 L208 V213 G215 F216 R217V66-V120 HydrophobicContact CG2-CB 4.46Å; V66-V120 HydrophobicContact CG2-CG2 3.87Å; P69-V120 HydrophobicContact CG-CG1 3.75Å; P69-V120 HydrophobicContact CG-CG2 4.27Å; F104-V120 HydrophobicContact CE2-CG2 4.5Å; F104-V120 HydrophobicContact CZ-CG2 3.79Å; V120-A122 PolarHBondContact O-N 2.96Å; V120-L208 HydrophobicContact CB-CD1 4.36Å; V120-L208 HydrophobicContact CG1-CD1 3.92Å; V120-L208 HydrophobicContact CG2-CD1 4.34Å; V120-L208 HydrophobicContact CG2-CD2 4.47Å; V120-V213 HydrophobicContact CB-CG1 4.23Å; V120-V213 HydrophobicContact CG2-CG1 3.82Å; V120-V213 HydrophobicContact CG2-CG2 3.82Å; V120-G215 PolarHBondContact N-O 2.92Å; V120-F216 HydrophobicContact CB-CD1 3.92Å; V120-F216 HydrophobicContact CB-CE1 4.21Å; V120-F216 HydrophobicContact CG1-CD1 4.31Å; V120-F216 CarbonylContact O-C 3.57Å; V120-F216 VanDerWaalsContact O-CA 3.24Å; V120-F216 WeakPolarHBondContact O-CA 3.36Å; V120-R217 PolarHBondContact O-N 2.79Å
121D98.8Very high98.2Very high0 Ų018.2 Ų18.20%010%0.101CC..EExtended strand (participates in β ladder)trans-73.2109.3163.7-159.9-16.3000109.5Q65 V66 P68 Y87 R217Q65-D121 PolarHBondContact NE2-OD2 2.94Å; V66-D121 WeakPolarHBondContact O-CB 3.25Å; V66-D121 PolarHBondContact O-N 2.85Å; P68-D121 VanDerWaalsContact CA-O 3.23Å; P68-D121 WeakPolarHBondContact CA-O 3.3Å; P68-D121 WeakPolarHBondContact CB-O 3.48Å; P68-D121 HydrophobicContact CG-CB 4.09Å; Y87-D121 WeakPolarHBondContact CE1-OD2 3.5Å; Y87-D121 PolarHBondContact OH-OD2 2.99Å; D121-R217 VanDerWaalsContact CG-NH1 3.34Å; D121-R217 WeakPolarHBondContact OD1-CD 3.42Å; D121-R217 IonicContact OD1-CZ 3.83Å; D121-R217 IonicContact OD1-NE 3.54Å; D121-R217 IonicContact OD1-NH1 2.65Å; D121-R217 PolarHBondContact OD1-NH1 2.69Å; D121-R217 IonicContact OD2-CZ 2.74Å; D121-R217 IonicContact OD2-NH1 2.87Å; D121-R217 PolarHBondContact OD2-NH1 3.29Å
122A98.8Very high98Very high0 Ų020.6 Ų20.60%011%0.113CC..EExtended strand (participates in β ladder)trans-106.4107.7-168.600000111V120 I124 L205 F216 R217 I218 D219V120-A122 PolarHBondContact O-N 2.96Å; A122-I124 HydrophobicContact CB-CG2 4.33Å; A122-I124 PolarHBondContact O-N 3.2Å; A122-L205 HydrophobicContact CB-CD2 4.02Å; A122-F216 HydrophobicContact CB-CB 4.28Å; A122-F216 HydrophobicContact CB-CD1 4.26Å; A122-R217 PolarHBondContact N-O 3.03Å; A122-I218 HydrophobicContact CB-CD1 4.22Å; A122-D219 WeakPolarHBondContact O-CB 3.41Å; A122-D219 PolarHBondContact O-N 3.43Å
123V98.8Very high97.9Very high0 Ų025.6 Ų25.60%014%0.136CC..  trans-86.9101.3174.5-172.80000109.4P68 Y87 P89 H126 D219P68-V123 HydrophobicContact CB-CG2 4.04Å; P68-V123 HydrophobicContact CG-CG2 3.62Å; Y87-V123 HydrophobicContact CD1-CG2 3.74Å; Y87-V123 HydrophobicContact CE1-CG2 4.41Å; Y87-V123 HydrophobicContact CG-CG2 4.4Å; P89-V123 HydrophobicContact CG-CB 3.8Å; P89-V123 HydrophobicContact CG-CG1 3.67Å; V123-H126 VanDerWaalsContact CG1-NE2 3.3Å; V123-H126 WeakPolarHBondContact CG1-NE2 3.46Å; V123-D219 HydrophobicContact CB-CB 4.49Å; V123-D219 HydrophobicContact CG2-CB 3.98Å
124I98.6Very high97.8Very high1 Ų120.6 Ų20.61%0.00512%0.119CC..  trans-126.8-4.4-175.565.5167.1000113.7A122 L190 V201 I218 M224 I232A122-I124 HydrophobicContact CB-CG2 4.33Å; A122-I124 PolarHBondContact O-N 3.2Å; I124-L190 WeakPolarHBondContact O-CD1 3.33Å; I124-V201 HydrophobicContact CB-CG1 3.79Å; I124-V201 HydrophobicContact CB-CG2 4.45Å; I124-V201 HydrophobicContact CD1-CG1 4.09Å; I124-V201 HydrophobicContact CG2-CG1 3.56Å; I124-I218 HydrophobicContact CD1-CD1 4.2Å; I124-I218 HydrophobicContact CD1-CG2 3.89Å; I124-I218 HydrophobicContact CG1-CG2 3.99Å; I124-M224 HydrophobicContact CD1-CE 4.33Å; I124-M224 HydrophobicContact CD1-SD 4.23Å; I124-M224 HydrophobicContact CG1-CE 3.86Å; I124-M224 HydrophobicContact CG1-SD 3.86Å; I124-I232 HydrophobicContact CD1-CD1 4.23Å
125N98.6Very high97.7Very high3 Ų325.3 Ų25.32%0.01614%0.139CC..SBendtrans-76.6-39.4174.7-177.391.1000112.1D189 L190 A220 H223 M224N125-D189 PolarHBondContact ND2-OD1 2.8Å; N125-L190 WeakPolarHBondContact O-CB 3.3Å; N125-L190 PolarHBondContact O-N 3.27Å; N125-A220 HydrophobicContact CB-CB 4.07Å; N125-H223 VanDerWaalsContact OD1-CB 3.24Å; N125-H223 WeakPolarHBondContact OD1-CB 3.47Å; N125-H223 PolarHBondContact OD1-O 3.03Å; N125-H223 VanDerWaalsContact OD1-O 3.05Å; N125-M224 HydrophobicContact CB-CE 4.06Å; N125-M224 HydrophobicContact CB-CG 3.88Å; N125-M224 HydrophobicContact CB-SD 3.89Å; N125-M224 WeakPolarHBondContact OD1-CG 3.35Å
126H98.6Very high97.7Very high3 Ų324.6 Ų24.61%0.01413%0.132CC..EExtended strand (participates in β ladder)trans-143.7171.2-167.958.7-99.2000112.1Y87 V123 L187 M188 D219Y87-H126 PolarHBondContact O-NE2 3.45Å; V123-H126 VanDerWaalsContact CG1-NE2 3.3Å; V123-H126 WeakPolarHBondContact CG1-NE2 3.46Å; H126-L187 HydrophobicContact CB-CB 3.84Å; H126-L187 WeakPolarHBondContact NE2-CD1 3.38Å; H126-M188 CarbonylContact C-O 3.54Å; H126-M188 WeakPolarHBondContact CA-O 3.48Å; H126-M188 VanDerWaalsContact CB-O 3.29Å; H126-M188 WeakPolarHBondContact CB-O 3.13Å; H126-D219 IonicContact CE1-OD2 2.77Å
127M98.3Very high97.6Very high0 Ų026.1 Ų26.10%014%0.142CC..EExtended strand (participates in β ladder)trans-116.6-150.6172.9-59.1-66.4-70.300110.2P89 Y151 V154 Y156 F161 M188 L190P89-M127 HydrophobicContact CB-CE 4.02Å; P89-M127 HydrophobicContact CB-SD 3.86Å; P89-M127 CarbonylContact O-C 3.47Å; M127-Y151 HydrophobicContact CB-CE1 3.96Å; M127-Y151 HydrophobicContact CB-CE2 4.48Å; M127-Y151 HydrophobicContact CE-CD1 3.86Å; M127-Y151 HydrophobicContact CE-CE1 4.05Å; M127-Y151 HydrophobicContact CE-CG 4.34Å; M127-V154 HydrophobicContact CE-CG1 3.85Å; M127-Y156 HydrophobicContact CE-CD2 4.21Å; M127-Y156 HydrophobicContact CE-CE2 4.39Å; M127-Y156 HydrophobicContact CG-CD2 4.48Å; M127-Y156 HydrophobicContact SD-CD2 4.28Å; M127-Y156 HydrophobicContact SD-CE2 4.09Å; M127-F161 HydrophobicContact CB-CE1 4.07Å; M127-F161 HydrophobicContact CB-CZ 4.42Å; M127-F161 HydrophobicContact CG-CE1 3.72Å; M127-F161 HydrophobicContact CG-CZ 3.97Å; M127-M188 HydrophobicContact CB-CB 4.29Å; M127-M188 PolarHBondContact N-O 2.64Å; M127-L190 HydrophobicContact CG-CD1 4.21Å; M127-L190 HydrophobicContact CG-CD2 3.87Å; M127-L190 HydrophobicContact CG-CG 4.07Å; M127-L190 HydrophobicContact SD-CD1 4.19Å
128T97.5Very high97.5Very high0 Ų025.2 Ų25.20%014%0.141CC..EExtended strand (participates in β ladder)trans-55.5162.1178.4620000114.2I73 P89 V90 Y142 S144 Y151 M188I73-T128 HydrophobicContact CB-CG2 4.04Å; I73-T128 HydrophobicContact CD1-CG2 3.98Å; I73-T128 HydrophobicContact CG1-CG2 4.29Å; P89-T128 WeakPolarHBondContact O-CG2 3.5Å; P89-T128 PolarHBondContact O-N 3.08Å; V90-T128 HydrophobicContact CG2-CG2 3.52Å; T128-Y142 HydrophobicContact CG2-CD2 3.87Å; T128-Y142 HydrophobicContact CG2-CE2 3.89Å; T128-Y142 HydrophobicContact CG2-CG 4.32Å; T128-S144 VanDerWaalsContact OG1-CB 3.26Å; T128-S144 WeakPolarHBondContact OG1-CB 3.42Å; T128-Y151 HydrophobicContact CG2-CE1 4.11Å; T128-Y151 PolarHBondContact OG1-OH 3.12Å; T128-M188 WeakPolarHBondContact O-CB 3.36Å; T128-M188 VanDerWaalsContact O-CG 3.24Å; T128-M188 WeakPolarHBondContact O-CG 3.33Å; T128-M188 PolarHBondContact O-N 3.03Å
129A95.4Very high97.4Very high12 Ų1227.2 Ų27.210%0.09916%0.162CC..EExtended strand (participates in β ladder)trans-54.3146.3163.700000112M132 S144 S186 L187A129-M132 HydrophobicContact CB-SD 3.89Å; A129-S144 VanDerWaalsContact O-CB 3.3Å; A129-S144 WeakPolarHBondContact O-CB 3.31Å; A129-S144 PolarHBondContact O-OG 3.07Å; A129-S186 CarbonylContact C-O 3.56Å; A129-S186 WeakPolarHBondContact CA-O 3.21Å; A129-L187 HydrophobicContact CB-CD2 4.37Å
130A95.4Very high97.4Very high14 Ų1427.3 Ų27.312%0.11616%0.163CC..SBendtrans-66.7157.2179.700000112.7M132 S144 S186 M188A130-M132 VanDerWaalsContact C-N 3.3Å; A130-M132 PolarHBondContact O-N 2.76Å; A130-S144 CarbonylContact C-O 3.55Å; A130-S144 WeakPolarHBondContact CA-O 3.4Å; A130-S186 WeakPolarHBondContact CB-O 3.26Å; A130-S186 PolarHBondContact N-O 3.16Å; A130-M188 HydrophobicContact CB-SD 3.49Å; A130-M188 WeakPolarHBondContact CB-SD 3.31Å
131N95.8Very high97.3Very high113 Ų11331.8 Ų31.860%0.60418%0.18SC*.SBendtrans59.234.9178.4-57.3-67.4000114.3S144 P146N131-S144 PolarHBondContact N-O 2.96Å; N131-P146 WeakPolarHBondContact OD1-CD 3.31Å
132M95Very high97.3Very high50 Ų5032.1 Ų32.125%0.24618%0.181CC..  trans-119.7157.7176.2-61.4-165.271.200110.9I73 F75 A129 A130 Y142 S144I73-M132 HydrophobicContact CD1-CB 4.43Å; I73-M132 HydrophobicContact CD1-CE 3.7Å; I73-M132 HydrophobicContact CD1-SD 3.56Å; I73-M132 VanDerWaalsContact CD1-SD 3.56Å; F75-M132 HydrophobicContact CD1-CE 3.77Å; F75-M132 HydrophobicContact CE1-CE 3.59Å; F75-M132 HydrophobicContact CE1-SD 4.11Å; F75-M132 HydrophobicContact CG-CE 4.36Å; F75-M132 HydrophobicContact CZ-CE 4.04Å; F75-M132 HydrophobicContact CZ-SD 4.39Å; A129-M132 HydrophobicContact CB-SD 3.89Å; A130-M132 VanDerWaalsContact C-N 3.3Å; A130-M132 PolarHBondContact O-N 2.76Å; M132-Y142 HydrophobicContact CB-CE2 3.88Å; M132-S144 WeakPolarHBondContact CA-OG 3.46Å; M132-S144 WeakPolarHBondContact CB-OG 3.49Å; M132-S144 PolarHBondContact N-OG 3.16Å; M132-S144 PolarHBondContact O-N 2.78Å; M132-S144 PolarHBondContact O-OG 2.71Å; M132-S144 VanDerWaalsContact O-OG 3.05Å
133Q96.5Very high97.3Very high127 Ų12733.4 Ų33.459%0.59319%0.188SC*.EExtended strand (participates in β ladder)trans-150147.1170.960.9179.539.800109Y142 N143Q133-Y142 VanDerWaalsContact CA-O 3.25Å; Q133-Y142 WeakPolarHBondContact CA-O 3.26Å; Q133-N143 HydrophobicContact CB-CB 4.45Å
134G96.6Very high97.2Very high24 Ų2433.4 Ų33.425%0.24719%0.188CC..EExtended strand (participates in β ladder)trans164-158.8-179.800000112.9Y141 Y142G134-Y141 WeakPolarHBondContact O-CA 3.21Å; G134-Y141 WeakPolarHBondContact O-CD2 3.13Å; G134-Y142 VanDerWaalsContact C-CE1 3.42Å; G134-Y142 PolarHBondContact N-O 3.17Å; G134-Y142 VanDerWaalsContact N-O 3.09Å; G134-Y142 VanDerWaalsContact O-CD1 3.24Å; G134-Y142 WeakPolarHBondContact O-CD1 3.39Å; G134-Y142 WeakPolarHBondContact O-CE1 3.47Å; G134-Y142 PolarHBondContact O-N 2.95Å
135Q97.2Very high97.1Very high133 Ų13335.3 Ų35.362%0.62120%0.2SC*.EExtended strand (participates in β ladder)trans-111.5138.6173.7-70.7177.9-30.600109.6S140Q135-S140 CarbonylContact C-O 3.52Å; Q135-S140 VanDerWaalsContact CA-O 3.31Å; Q135-S140 WeakPolarHBondContact CA-O 3.44Å
136G97.3Very high96.9Very high8 Ų836.1 Ų36.18%0.08221%0.205CC..BIsolated β-bridgetrans-76.2178.5170.900000112.3E71 H72 G138 G139 S140E71-G136 VanDerWaalsContact OE1-C 3.26Å; E71-G136 VanDerWaalsContact OE1-CA 3.27Å; E71-G136 WeakPolarHBondContact OE1-CA 3.49Å; H72-G136 CarbonylContact O-C 3.55Å; H72-G136 VanDerWaalsContact O-CA 3.29Å; H72-G136 WeakPolarHBondContact O-CA 3.48Å; G136-G138 PolarHBondContact O-N 3.19Å; G136-G139 PolarHBondContact O-N 3.31Å; G136-S140 PolarHBondContact N-O 3.02Å
137S96.3Very high96.8Very high32 Ų3242 Ų4222%0.22423%0.231CC..THydrogen-bonded Turntrans-59.1-24.2178.549.70000114.3H72 E95H72-S137 PolarHBondContact N-OG 2.8Å; H72-S137 PolarHBondContact O-N 2.93Å; H72-S137 PolarHBondContact O-OG 3.46Å; E95-S137 PolarHBondContact O-OG 2.77Å
138G96.8Very high96.7Very high7 Ų749 Ų497%0.07226%0.261CS..THydrogen-bonded Turntrans-106.724.217700000113.8E71 K93 E95 G136 S140E71-G138 VanDerWaalsContact CG-N 3.34Å; E71-G138 VanDerWaalsContact OE1-CA 3.27Å; E71-G138 WeakPolarHBondContact OE1-CA 3.42Å; E71-G138 PolarHBondContact OE1-N 2.84Å; K93-G138 PolarHBondContact NZ-O 3.29Å; E95-G138 WeakPolarHBondContact OE2-CA 3.38Å; G136-G138 PolarHBondContact O-N 3.19Å; G138-S140 PolarHBondContact O-N 2.62Å
139G97.4Very high96.6Very high43 Ų4349.3 Ų49.344%0.44326%0.263SS..SBendtrans73.82.7171.900000115.6E71 G136E71-G139 PolarHBondContact OE1-N 3.03Å; E71-G139 VanDerWaalsContact OE1-N 3.12Å; G136-G139 PolarHBondContact O-N 3.31Å
140S98.3Very high96.8Very high4 Ų453.8 Ų53.83%0.02828%0.28CS..  trans-73.3136.2-179.8-520000110.5E71 K93 Q135 G136 G138 A153E71-S140 WeakPolarHBondContact OE1-CB 3.1Å; E71-S140 PolarHBondContact OE1-N 3.09Å; E71-S140 PolarHBondContact OE1-OG 2.82Å; E71-S140 WeakPolarHBondContact OE2-CB 3.32Å; E71-S140 PolarHBondContact OE2-OG 2.93Å; K93-S140 WeakPolarHBondContact CE-OG 3.41Å; K93-S140 PolarHBondContact NZ-OG 3.03Å; Q135-S140 CarbonylContact C-O 3.52Å; Q135-S140 VanDerWaalsContact CA-O 3.31Å; Q135-S140 WeakPolarHBondContact CA-O 3.44Å; G136-S140 PolarHBondContact N-O 3.02Å; G138-S140 PolarHBondContact O-N 2.62Å; S140-A153 WeakPolarHBondContact OG-CB 2.99Å
141Y98Very high96.9Very high94 Ų9453.1 Ų53.137%0.36928%0.275SS..EExtended strand (participates in β ladder)trans-79.3141.3176.3179-97.2000110.6G134 N143 F150 S152G134-Y141 WeakPolarHBondContact O-CA 3.21Å; G134-Y141 WeakPolarHBondContact O-CD2 3.13Å; Y141-N143 HydrophobicContact CE1-CB 4.24Å; Y141-F150 AromaticContact CD1-CD1 3.99Å; Y141-F150 HydrophobicContact CD1-CD1 3.99Å; Y141-F150 HydrophobicContact CD1-CE1 4.17Å; Y141-F150 HydrophobicContact CE1-CD1 4.19Å; Y141-S152 PolarHBondContact N-OG 2.78Å; Y141-S152 WeakPolarHBondContact O-CB 3.23Å; Y141-S152 PolarHBondContact O-N 3.22Å; Y141-S152 PolarHBondContact O-OG 3.34Å
142Y98.2Very high97Very high6 Ų650.4 Ų50.42%0.02427%0.265CS..EExtended strand (participates in β ladder)trans-137.3154.1169.872.2-78000111.9I73 V90 T128 M132 Q133 G134 F150 Y151I73-Y142 HydrophobicContact CD1-CE2 3.98Å; I73-Y142 WeakPolarHBondContact CD1-OH 3.41Å; I73-Y142 HydrophobicContact CG1-CE1 4.17Å; I73-Y142 HydrophobicContact CG1-CE2 4.48Å; I73-Y142 VanDerWaalsContact CG1-OH 3.23Å; I73-Y142 WeakPolarHBondContact CG1-OH 3.38Å; V90-Y142 HydrophobicContact CB-CD1 4.37Å; V90-Y142 HydrophobicContact CG1-CD1 3.82Å; V90-Y142 HydrophobicContact CG1-CG 4.26Å; V90-Y142 HydrophobicContact CG2-CD1 3.61Å; V90-Y142 HydrophobicContact CG2-CE1 3.89Å; V90-Y142 HydrophobicContact CG2-CG 4.12Å; T128-Y142 HydrophobicContact CG2-CD2 3.87Å; T128-Y142 HydrophobicContact CG2-CE2 3.89Å; T128-Y142 HydrophobicContact CG2-CG 4.32Å; M132-Y142 HydrophobicContact CB-CE2 3.88Å; Q133-Y142 VanDerWaalsContact CA-O 3.25Å; Q133-Y142 WeakPolarHBondContact CA-O 3.26Å; G134-Y142 VanDerWaalsContact C-CE1 3.42Å; G134-Y142 PolarHBondContact N-O 3.17Å; G134-Y142 VanDerWaalsContact N-O 3.09Å; G134-Y142 VanDerWaalsContact O-CD1 3.24Å; G134-Y142 WeakPolarHBondContact O-CD1 3.39Å; G134-Y142 WeakPolarHBondContact O-CE1 3.47Å; G134-Y142 PolarHBondContact O-N 2.95Å; Y142-F150 CarbonylContact C-O 3.52Å; Y142-F150 VanDerWaalsContact CA-O 3.25Å; Y142-F150 WeakPolarHBondContact CA-O 3.42Å; Y142-Y151 HydrophobicContact CD2-CE1 4.3Å; Y142-Y151 HydrophobicContact CG-CE1 4.31Å
143N98.1Very high97.1Very high28 Ų2850.1 Ų50.115%0.1527%0.27CS..EExtended strand (participates in β ladder)trans-134.4118165.3-177.6-6.7000107.1Q133 Y141 T145 E149 F150Q133-N143 HydrophobicContact CB-CB 4.45Å; Y141-N143 HydrophobicContact CE1-CB 4.24Å; N143-T145 WeakPolarHBondContact OD1-CB 3.25Å; N143-T145 PolarHBondContact OD1-N 3.08Å; N143-T145 PolarHBondContact OD1-OG1 3.19Å; N143-E149 CarbonylContact O-C 3.55Å; N143-E149 VanDerWaalsContact O-CA 3.24Å; N143-E149 WeakPolarHBondContact O-CA 3.48Å; N143-F150 HydrophobicContact CB-CB 4.45Å; N143-F150 PolarHBondContact N-O 2.88Å; N143-F150 PolarHBondContact O-N 2.74Å
144S96.8Very high97.1Very high0 Ų044.4 Ų44.40%024%0.244CC..  trans-106.925.1178.661.50000112.1T128 A129 A130 N131 M132 P146 Y151T128-S144 VanDerWaalsContact OG1-CB 3.26Å; T128-S144 WeakPolarHBondContact OG1-CB 3.42Å; A129-S144 VanDerWaalsContact O-CB 3.3Å; A129-S144 WeakPolarHBondContact O-CB 3.31Å; A129-S144 PolarHBondContact O-OG 3.07Å; A130-S144 CarbonylContact C-O 3.55Å; A130-S144 WeakPolarHBondContact CA-O 3.4Å; N131-S144 PolarHBondContact N-O 2.96Å; M132-S144 WeakPolarHBondContact CA-OG 3.46Å; M132-S144 WeakPolarHBondContact CB-OG 3.49Å; M132-S144 PolarHBondContact N-OG 3.16Å; M132-S144 PolarHBondContact O-N 2.78Å; M132-S144 PolarHBondContact O-OG 2.71Å; M132-S144 VanDerWaalsContact O-OG 3.05Å; S144-P146 WeakPolarHBondContact O-CD 3.41Å; S144-Y151 WeakPolarHBondContact CB-OH 3.47Å
145T96.7Very high96.9Very high40 Ų4047.5 Ų47.525%0.24526%0.26CS..  trans-67126.4170.9-58.20000109.1N143 F147 K148 E149N143-T145 WeakPolarHBondContact OD1-CB 3.25Å; N143-T145 PolarHBondContact OD1-N 3.08Å; N143-T145 PolarHBondContact OD1-OG1 3.19Å; T145-F147 PolarHBondContact O-N 2.03Å; T145-K148 HydrophobicContact CG2-CB 4.37Å; T145-K148 HydrophobicContact CG2-CD 4.29Å; T145-K148 CarbonylContact O-C 3.48Å; T145-K148 VanDerWaalsContact O-C 3.27Å; T145-K148 WeakPolarHBondContact O-CA 3.25Å; T145-K148 PolarHBondContact O-N 2.62Å; T145-E149 PolarHBondContact O-N 2.88Å
146P94.3Very high96.9Very high20 Ų2041.2 Ų41.213%0.1323%0.23CC..THydrogen-bonded Turntrans-48.3134.4177.8-31.837.9000113.8N131 S144 K148 E149 D163 N167N131-P146 WeakPolarHBondContact OD1-CD 3.31Å; S144-P146 WeakPolarHBondContact O-CD 3.41Å; P146-K148 PolarHBondContact O-N 3.2Å; P146-E149 VanDerWaalsContact CA-OE1 3.26Å; P146-E149 WeakPolarHBondContact CA-OE1 3.23Å; P146-D163 WeakPolarHBondContact CA-OD2 3.42Å; P146-D163 VanDerWaalsContact CB-OD2 3.24Å; P146-D163 WeakPolarHBondContact CB-OD2 3.23Å; P146-N167 WeakPolarHBondContact CB-ND2 3.3Å
147F96.2Very high96.9Very high126 Ų12643 Ų4355%0.55324%0.242SC*.THydrogen-bonded Turntrans61.68.7-175.2-47.7-71.6000115.8T145 E149 D163 N167T145-F147 PolarHBondContact O-N 2.03Å; F147-E149 WeakPolarHBondContact CA-OE2 3.19Å; F147-E149 VanDerWaalsContact N-CD 3.25Å; F147-E149 PolarHBondContact N-OE1 2.99Å; F147-E149 PolarHBondContact N-OE2 3.16Å; F147-D163 HydrophobicContact CD1-CB 4.33Å; F147-D163 HydrophobicContact CE1-CB 4.06Å; F147-D163 WeakPolarHBondContact CE1-O 3.2Å; F147-N167 WeakPolarHBondContact CE2-ND2 3.37Å; F147-N167 HydrophobicContact CZ-CB 4.21Å; F147-N167 VanDerWaalsContact CZ-ND2 3.34Å; F147-N167 WeakPolarHBondContact CZ-ND2 3.21Å
148K96.4Very high96.9Very high148 Ų14843 Ų4364%0.64324%0.244SC*.  trans-136.421.8177.7-61.5-179.6-176.8173.90110.9T145 P146 F150T145-K148 HydrophobicContact CG2-CB 4.37Å; T145-K148 HydrophobicContact CG2-CD 4.29Å; T145-K148 CarbonylContact O-C 3.48Å; T145-K148 VanDerWaalsContact O-C 3.27Å; T145-K148 WeakPolarHBondContact O-CA 3.25Å; T145-K148 PolarHBondContact O-N 2.62Å; P146-K148 PolarHBondContact O-N 3.2Å; K148-F150 PolarHBondContact O-N 3.35Å
149E96.8Very high97Very high6 Ų648.6 Ų48.63%0.02827%0.268CS..  trans-58.8134.4-179.1-61.780.4173.300109.1N143 T145 P146 F147 Y151 S157 A158 F161 M188N143-E149 CarbonylContact O-C 3.55Å; N143-E149 VanDerWaalsContact O-CA 3.24Å; N143-E149 WeakPolarHBondContact O-CA 3.48Å; T145-E149 PolarHBondContact O-N 2.88Å; P146-E149 VanDerWaalsContact CA-OE1 3.26Å; P146-E149 WeakPolarHBondContact CA-OE1 3.23Å; F147-E149 WeakPolarHBondContact CA-OE2 3.19Å; F147-E149 VanDerWaalsContact N-CD 3.25Å; F147-E149 PolarHBondContact N-OE1 2.99Å; F147-E149 PolarHBondContact N-OE2 3.16Å; E149-Y151 HydrophobicContact CB-CE2 4.37Å; E149-S157 CarbonylContact O-C 3.55Å; E149-S157 VanDerWaalsContact O-CA 3.3Å; E149-S157 WeakPolarHBondContact O-CA 3.41Å; E149-A158 PolarHBondContact O-N 2.96Å; E149-A158 WeakPolarHBondContact OE2-CA 3.25Å; E149-A158 WeakPolarHBondContact OE2-CB 3.33Å; E149-F161 HydrophobicContact CB-CD2 3.64Å; E149-F161 HydrophobicContact CB-CE2 3.57Å; E149-F161 HydrophobicContact CG-CD2 3.59Å; E149-F161 HydrophobicContact CG-CE2 3.88Å; E149-F161 HydrophobicContact CG-CG 4.19Å; E149-M188 HydrophobicContact CG-CE 3.47Å; E149-M188 VanDerWaalsContact CG-CE 3.47Å; E149-M188 WeakPolarHBondContact OE1-CE 3.4Å
150F97.8Very high97Very high106 Ų10646.9 Ų46.947%0.46525%0.248SC..EExtended strand (participates in β ladder)trans-154.5121.8177.9179.4-101.9000109.3Y141 Y142 N143 K148 Y156Y141-F150 AromaticContact CD1-CD1 3.99Å; Y141-F150 HydrophobicContact CD1-CD1 3.99Å; Y141-F150 HydrophobicContact CD1-CE1 4.17Å; Y141-F150 HydrophobicContact CE1-CD1 4.19Å; Y142-F150 CarbonylContact C-O 3.52Å; Y142-F150 VanDerWaalsContact CA-O 3.25Å; Y142-F150 WeakPolarHBondContact CA-O 3.42Å; N143-F150 HydrophobicContact CB-CB 4.45Å; N143-F150 PolarHBondContact N-O 2.88Å; N143-F150 PolarHBondContact O-N 2.74Å; K148-F150 PolarHBondContact O-N 3.35Å; F150-Y156 WeakPolarHBondContact CA-O 3.23Å
151Y98.4Very high97Very high0 Ų046.7 Ų46.70%025%0.247CC..EExtended strand (participates in β ladder)trans-122117.5176.4-67.9-95.3000108.3V90 M127 T128 Y142 S144 E149 V154 P155 Y156 F161V90-Y151 VanDerWaalsContact O-CD1 3.31Å; V90-Y151 WeakPolarHBondContact O-CD1 3.06Å; M127-Y151 HydrophobicContact CB-CE1 3.96Å; M127-Y151 HydrophobicContact CB-CE2 4.48Å; M127-Y151 HydrophobicContact CE-CD1 3.86Å; M127-Y151 HydrophobicContact CE-CE1 4.05Å; M127-Y151 HydrophobicContact CE-CG 4.34Å; T128-Y151 HydrophobicContact CG2-CE1 4.11Å; T128-Y151 PolarHBondContact OG1-OH 3.12Å; Y142-Y151 HydrophobicContact CD2-CE1 4.3Å; Y142-Y151 HydrophobicContact CG-CE1 4.31Å; S144-Y151 WeakPolarHBondContact CB-OH 3.47Å; E149-Y151 HydrophobicContact CB-CE2 4.37Å; Y151-V154 CarbonylContact C-O 3.56Å; Y151-V154 VanDerWaalsContact CB-O 3.24Å; Y151-V154 WeakPolarHBondContact CB-O 3.1Å; Y151-V154 CarbonylContact O-C 3.33Å; Y151-P155 VanDerWaalsContact O-CA 3.26Å; Y151-P155 WeakPolarHBondContact O-CA 3.39Å; Y151-Y156 PolarHBondContact N-O 3.4Å; Y151-F161 AromaticContact CD2-CE2 3.99Å; Y151-F161 HydrophobicContact CD2-CE2 3.99Å; Y151-F161 AromaticContact CD2-CZ 3.72Å; Y151-F161 HydrophobicContact CD2-CZ 3.72Å; Y151-F161 HydrophobicContact CE2-CE1 4.19Å; Y151-F161 AromaticContact CE2-CE2 3.7Å; Y151-F161 HydrophobicContact CE2-CE2 3.7Å; Y151-F161 AromaticContact CE2-CZ 3.25Å; Y151-F161 HydrophobicContact CE2-CZ 3.25Å
152S97.4Very high97Very high56 Ų5642.7 Ų42.739%0.39223%0.232SC..SBendtrans-73.8-33.8-165.769.50000114.2Y141Y141-S152 PolarHBondContact N-OG 2.78Å; Y141-S152 WeakPolarHBondContact O-CB 3.23Å; Y141-S152 PolarHBondContact O-N 3.22Å; Y141-S152 PolarHBondContact O-OG 3.34Å
153A97.4Very high96.9Very high44 Ų4442.6 Ų42.636%0.36423%0.232SC..SBendtrans-98.4-12.9-172.700000114.3K93 S140K93-A153 HydrophobicContact CD-CB 4.46Å; S140-A153 WeakPolarHBondContact OG-CB 2.99Å
154V96.5Very high96.8Very high7 Ų746.3 Ų46.34%0.04225%0.252CS..SBendtrans-129.7101.9159.253.80000103.7Y92 M127 Y151 Y156 K200Y92-V154 HydrophobicContact CD2-CB 4.21Å; Y92-V154 HydrophobicContact CD2-CG2 3.87Å; Y92-V154 HydrophobicContact CE2-CB 4.47Å; Y92-V154 HydrophobicContact CE2-CG2 3.77Å; M127-V154 HydrophobicContact CE-CG1 3.85Å; Y151-V154 CarbonylContact C-O 3.56Å; Y151-V154 VanDerWaalsContact CB-O 3.24Å; Y151-V154 WeakPolarHBondContact CB-O 3.1Å; Y151-V154 CarbonylContact O-C 3.33Å; V154-Y156 HydrophobicContact CB-CD2 4.31Å; V154-Y156 HydrophobicContact CB-CE2 4.31Å; V154-Y156 HydrophobicContact CG1-CD2 3.7Å; V154-Y156 HydrophobicContact CG1-CE2 3.88Å; V154-Y156 HydrophobicContact CG2-CD1 4.42Å; V154-Y156 HydrophobicContact CG2-CD2 3.71Å; V154-Y156 HydrophobicContact CG2-CE1 4.2Å; V154-Y156 HydrophobicContact CG2-CE2 3.42Å; V154-Y156 VanDerWaalsContact CG2-CE2 3.42Å; V154-Y156 HydrophobicContact CG2-CG 4.19Å; V154-Y156 PolarHBondContact O-N 3.41Å; V154-K200 HydrophobicContact CG2-CB 4.29Å; V154-K200 HydrophobicContact CG2-CD 3.99Å; V154-K200 HydrophobicContact CG2-CG 4.38Å
155P91.7Very high96.8Very high89 Ų8949.3 Ų49.358%0.57827%0.267SS*.  trans-7265.6-164.430.1-36.3000111.5Y151 K200Y151-P155 VanDerWaalsContact O-CA 3.26Å; Y151-P155 WeakPolarHBondContact O-CA 3.39Å; P155-K200 PolarHBondContact O-NZ 2.66Å
156Y98Very high96.8Very high1 Ų147.5 Ų47.50%0.00426%0.256CS..  trans-80.1136.5166.9-67.8-45.5000108Y92 M127 F150 Y151 V154 D160 L190 V197 K200Y92-Y156 HydrophobicContact CE2-CE2 4.12Å; Y92-Y156 PolarHBondContact OH-OH 3.38Å; M127-Y156 HydrophobicContact CE-CD2 4.21Å; M127-Y156 HydrophobicContact CE-CE2 4.39Å; M127-Y156 HydrophobicContact CG-CD2 4.48Å; M127-Y156 HydrophobicContact SD-CD2 4.28Å; M127-Y156 HydrophobicContact SD-CE2 4.09Å; F150-Y156 WeakPolarHBondContact CA-O 3.23Å; Y151-Y156 PolarHBondContact N-O 3.4Å; V154-Y156 HydrophobicContact CB-CD2 4.31Å; V154-Y156 HydrophobicContact CB-CE2 4.31Å; V154-Y156 HydrophobicContact CG1-CD2 3.7Å; V154-Y156 HydrophobicContact CG1-CE2 3.88Å; V154-Y156 HydrophobicContact CG2-CD1 4.42Å; V154-Y156 HydrophobicContact CG2-CD2 3.71Å; V154-Y156 HydrophobicContact CG2-CE1 4.2Å; V154-Y156 HydrophobicContact CG2-CE2 3.42Å; V154-Y156 VanDerWaalsContact CG2-CE2 3.42Å; V154-Y156 HydrophobicContact CG2-CG 4.19Å; V154-Y156 PolarHBondContact O-N 3.41Å; Y156-D160 WeakPolarHBondContact CA-OD2 3.27Å; Y156-D160 HydrophobicContact CD1-CB 3.55Å; Y156-D160 HydrophobicContact CE1-CB 4.37Å; Y156-D160 HydrophobicContact CG-CB 4.1Å; Y156-L190 HydrophobicContact CD2-CD2 3.99Å; Y156-L190 HydrophobicContact CE1-CD2 4.4Å; Y156-L190 HydrophobicContact CE2-CD2 3.8Å; Y156-L190 HydrophobicContact CG-CD2 4.41Å; Y156-V197 HydrophobicContact CE1-CB 4.29Å; Y156-V197 HydrophobicContact CE1-CG1 3.95Å; Y156-V197 HydrophobicContact CE1-CG2 4.1Å; Y156-K200 HydrophobicContact CD1-CD 3.74Å; Y156-K200 VanDerWaalsContact CD1-NZ 3.35Å; Y156-K200 HydrophobicContact CE1-CB 4.14Å; Y156-K200 HydrophobicContact CE1-CD 3.21Å; Y156-K200 HydrophobicContact CE1-CG 4.33Å; Y156-K200 WeakPolarHBondContact OH-CB 3.13Å
157S97.3Very high96.9Very high46 Ų4649.4 Ų49.432%0.32227%0.266SS..BIsolated β-bridgetrans-121.9178.5178.666.80000109.1E149 E159 D160 F161E149-S157 CarbonylContact O-C 3.55Å; E149-S157 VanDerWaalsContact O-CA 3.3Å; E149-S157 WeakPolarHBondContact O-CA 3.41Å; S157-E159 PolarHBondContact O-N 2.73Å; S157-D160 PolarHBondContact N-OD2 3.03Å; S157-D160 WeakPolarHBondContact O-CB 3.5Å; S157-D160 PolarHBondContact O-N 3Å; S157-D160 PolarHBondContact OG-OD2 3.05Å; S157-F161 WeakPolarHBondContact O-CD2 3.46Å; S157-F161 WeakPolarHBondContact O-CE2 3.37Å
158A97.2Very high96.9Very high32 Ų3248.6 Ų48.626%0.26426%0.259SS..G310 helixtrans-50.9-31177.400000114.9E149 D160E149-A158 PolarHBondContact O-N 2.96Å; E149-A158 WeakPolarHBondContact OE2-CA 3.25Å; E149-A158 WeakPolarHBondContact OE2-CB 3.33Å; A158-D160 VanDerWaalsContact C-N 3.27Å; A158-D160 PolarHBondContact O-N 2.66Å
159E97.5Very high96.9Very high125 Ų12544 Ų4458%0.58424%0.241SC*.G310 helixtrans-78.6-10.1-178.3-46.7-179.3169.500114.2S157 F161 R194S157-E159 PolarHBondContact O-N 2.73Å; E159-F161 VanDerWaalsContact C-N 3.33Å; E159-R194 WeakPolarHBondContact O-CD 3.43Å; E159-R194 PolarHBondContact O-NH1 2.85Å; E159-R194 IonicContact OE2-CZ 3.02Å; E159-R194 IonicContact OE2-NH1 3.8Å; E159-R194 PolarHBondContact OE2-NH1 3.25Å; E159-R194 IonicContact OE2-NH2 3.88Å
160D98.3Very high96.9Very high6 Ų644.5 Ų44.53%0.03224%0.244CC..G310 helixtrans-89.8-0.2179.5-61.3-85.8000112.2Y156 S157 A158 K191 V197 K200Y156-D160 WeakPolarHBondContact CA-OD2 3.27Å; Y156-D160 HydrophobicContact CD1-CB 3.55Å; Y156-D160 HydrophobicContact CE1-CB 4.37Å; Y156-D160 HydrophobicContact CG-CB 4.1Å; S157-D160 PolarHBondContact N-OD2 3.03Å; S157-D160 WeakPolarHBondContact O-CB 3.5Å; S157-D160 PolarHBondContact O-N 3Å; S157-D160 PolarHBondContact OG-OD2 3.05Å; A158-D160 VanDerWaalsContact C-N 3.27Å; A158-D160 PolarHBondContact O-N 2.66Å; D160-K191 WeakPolarHBondContact O-CB 3.27Å; D160-K191 PolarHBondContact O-N 2.91Å; D160-V197 HydrophobicContact CB-CG2 3.87Å; D160-K200 IonicContact OD1-NZ 3.2Å
161F98.4Very high96.8Very high0 Ų042.7 Ų42.70%026%0.255CS..BIsolated β-bridgetrans-117.3156.7179.4-62.3-84.2000111.4M127 E149 Y151 S157 E159 D163 M188 D189 L190M127-F161 HydrophobicContact CB-CE1 4.07Å; M127-F161 HydrophobicContact CB-CZ 4.42Å; M127-F161 HydrophobicContact CG-CE1 3.72Å; M127-F161 HydrophobicContact CG-CZ 3.97Å; E149-F161 HydrophobicContact CB-CD2 3.64Å; E149-F161 HydrophobicContact CB-CE2 3.57Å; E149-F161 HydrophobicContact CG-CD2 3.59Å; E149-F161 HydrophobicContact CG-CE2 3.88Å; E149-F161 HydrophobicContact CG-CG 4.19Å; Y151-F161 AromaticContact CD2-CE2 3.99Å; Y151-F161 HydrophobicContact CD2-CE2 3.99Å; Y151-F161 AromaticContact CD2-CZ 3.72Å; Y151-F161 HydrophobicContact CD2-CZ 3.72Å; Y151-F161 HydrophobicContact CE2-CE1 4.19Å; Y151-F161 AromaticContact CE2-CE2 3.7Å; Y151-F161 HydrophobicContact CE2-CE2 3.7Å; Y151-F161 AromaticContact CE2-CZ 3.25Å; Y151-F161 HydrophobicContact CE2-CZ 3.25Å; S157-F161 WeakPolarHBondContact O-CD2 3.46Å; S157-F161 WeakPolarHBondContact O-CE2 3.37Å; E159-F161 VanDerWaalsContact C-N 3.33Å; F161-D163 PolarHBondContact O-N 3.3Å; F161-D163 VanDerWaalsContact O-N 3.16Å; F161-M188 HydrophobicContact CB-CE 4.38Å; F161-M188 HydrophobicContact CD1-CB 3.77Å; F161-M188 HydrophobicContact CD1-CE 4.21Å; F161-M188 HydrophobicContact CE1-CB 3.66Å; F161-M188 HydrophobicContact CG-CE 4.17Å; F161-D189 CarbonylContact C-O 3.56Å; F161-D189 VanDerWaalsContact CA-O 3.23Å; F161-D189 WeakPolarHBondContact CA-O 3.26Å; F161-D189 WeakPolarHBondContact CB-O 3.5Å; F161-D189 WeakPolarHBondContact CD1-O 3.32Å; F161-L190 HydrophobicContact CD1-CD2 4.11Å; F161-L190 HydrophobicContact CE1-CD2 3.61Å; F161-L190 HydrophobicContact CE1-CG 4.27Å; F161-L190 HydrophobicContact CZ-CD2 4.04Å
162N97.8Very high96.6Very high10 Ų1046 Ų465%0.05327%0.273CS..THydrogen-bonded Turntrans-77.413.6179.3-80.8-35.2000113.7D164 I165 C166 N181 D189 L190 K191N162-D164 PolarHBondContact O-N 2.79Å; N162-I165 CarbonylContact O-C 3.54Å; N162-I165 WeakPolarHBondContact O-CA 2.83Å; N162-I165 WeakPolarHBondContact O-CB 3.31Å; N162-I165 PolarHBondContact O-N 3.02Å; N162-C166 PolarHBondContact O-N 3.22Å; N162-N181 WeakPolarHBondContact CB-O 3.47Å; N162-D189 HydrophobicContact CB-CB 4.46Å; N162-D189 PolarHBondContact N-O 3.32Å; N162-D189 PolarHBondContact ND2-OD2 2.73Å; N162-L190 PolarHBondContact ND2-O 3.19Å; N162-K191 VanDerWaalsContact OD1-CG 3.28Å; N162-K191 WeakPolarHBondContact OD1-CG 3.48Å
163D95.9Very high96.5Very high4 Ų447.7 Ų47.72%0.02127%0.271CS..Hα-helixtrans-60.9-26.6-177.8-95.338.2000114P146 F147 F161 I165 N167 R183P146-D163 WeakPolarHBondContact CA-OD2 3.42Å; P146-D163 VanDerWaalsContact CB-OD2 3.24Å; P146-D163 WeakPolarHBondContact CB-OD2 3.23Å; F147-D163 HydrophobicContact CD1-CB 4.33Å; F147-D163 HydrophobicContact CE1-CB 4.06Å; F147-D163 WeakPolarHBondContact CE1-O 3.2Å; F161-D163 PolarHBondContact O-N 3.3Å; F161-D163 VanDerWaalsContact O-N 3.16Å; D163-I165 VanDerWaalsContact C-N 3.3Å; D163-N167 HydrophobicContact CB-CB 4.45Å; D163-N167 WeakPolarHBondContact O-CB 3.41Å; D163-R183 IonicContact OD1-CZ 3.8Å; D163-R183 IonicContact OD1-NE 3.58Å; D163-R183 IonicContact OD1-NH2 3.6Å; D163-R183 PolarHBondContact OD1-NH2 2.94Å; D163-R183 IonicContact OD2-CZ 3.69Å; D163-R183 IonicContact OD2-NH2 2.74Å; D163-R183 PolarHBondContact OD2-NH2 3.47Å
164D96.3Very high96.4Very high106 Ų10651.1 Ų51.157%0.56728%0.284SS*.Hα-helixtrans-75.5-19172.270.5-46.4000113.4N162 K191N162-D164 PolarHBondContact O-N 2.79Å; D164-K191 IonicContact OD1-NZ 2.96Å; D164-K191 PolarHBondContact OD1-NZ 3.45Å; D164-K191 IonicContact OD2-NZ 3.54Å; D164-K191 PolarHBondContact OD2-NZ 2.7Å
165I96.7Very high96.5Very high63 Ų6353.5 Ų53.532%0.32330%0.296SS..Hα-helixtrans-98.9-50.1180-64.7171.4000110.8N162 D163 W177 N181N162-I165 CarbonylContact O-C 3.54Å; N162-I165 WeakPolarHBondContact O-CA 2.83Å; N162-I165 WeakPolarHBondContact O-CB 3.31Å; N162-I165 PolarHBondContact O-N 3.02Å; D163-I165 VanDerWaalsContact C-N 3.3Å; I165-W177 HydrophobicContact CG2-CH2 4.35Å; I165-W177 HydrophobicContact CG2-CZ2 3.68Å; I165-N181 HydrophobicContact CG2-CB 4.03Å
166C97.8Very high96.7Very high3 Ų351.7 Ų51.72%0.0228%0.284CS..Hα-helixtrans-148.588.9179.5-169.40000112.5N162 R168 W177 N181 C182N162-C166 PolarHBondContact O-N 3.22Å; C166-R168 VanDerWaalsContact C-N 3.27Å; C166-R168 PolarHBondContact O-N 2.74Å; C166-R168 VanDerWaalsContact O-N 3.1Å; C166-R168 WeakPolarHBondContact SG-CG 3.28Å; C166-R168 VanDerWaalsContact SG-CZ 3.55Å; C166-R168 PolarHBondContact SG-NH1 2.73Å; C166-W177 HydrophobicContact CB-CH2 3.96Å; C166-W177 HydrophobicContact CB-CZ3 4.4Å; C166-N181 HydrophobicContact CB-CB 4.49Å; C166-N181 WeakPolarHBondContact CB-O 3.4Å; C166-C182 HydrophobicContact CB-CB 3.99Å; C166-C182 WeakPolarHBondContact CB-SG 3.14Å; C166-C182 VanDerWaalsContact SG-CA 3.55Å; C166-C182 WeakPolarHBondContact SG-CB 3.32Å; C166-C182 CovalentContact SG-SG 2.03Å; C166-C182 PolarHBondContact SG-SG 2.94Å
167N95.3Very high96.7Very high60 Ų6056.4 Ų56.432%0.32130%0.302SS..  trans-85.962.3170.3-172.6-4.1000112.2P146 F147 D163 R183P146-N167 WeakPolarHBondContact CB-ND2 3.3Å; F147-N167 WeakPolarHBondContact CE2-ND2 3.37Å; F147-N167 HydrophobicContact CZ-CB 4.21Å; F147-N167 VanDerWaalsContact CZ-ND2 3.34Å; F147-N167 WeakPolarHBondContact CZ-ND2 3.21Å; D163-N167 HydrophobicContact CB-CB 4.45Å; D163-N167 WeakPolarHBondContact O-CB 3.41Å; N167-R183 VanDerWaalsContact OD1-CZ 3.28Å; N167-R183 PolarHBondContact OD1-NH1 3.48Å; N167-R183 PolarHBondContact OD1-NH2 3.21Å; N167-R183 VanDerWaalsContact OD1-NH2 3.1Å
168R96.1Very high96.7Very high109 Ų10955.4 Ų55.441%0.41129%0.293SS..SBendtrans-157.9168.7170.363.9174.2-171.7-69.42.2110.1C166 E178 R183C166-R168 VanDerWaalsContact C-N 3.27Å; C166-R168 PolarHBondContact O-N 2.74Å; C166-R168 VanDerWaalsContact O-N 3.1Å; C166-R168 WeakPolarHBondContact SG-CG 3.28Å; C166-R168 VanDerWaalsContact SG-CZ 3.55Å; C166-R168 PolarHBondContact SG-NH1 2.73Å; R168-E178 IonicContact CZ-OE1 2.78Å; R168-E178 IonicContact NE-OE1 3.57Å; R168-E178 IonicContact NH2-OE1 2.74Å; R168-E178 PolarHBondContact NH2-OE1 3.39Å; R168-R183 PolarHBondContact O-N 3Å
169D96.9Very high96.8Very high51 Ų5153.9 Ų53.927%0.27328%0.28SS..BIsolated β-bridgetrans-73.1154.5169.9-70.83.2000111.3G171 R183 S186D169-G171 PolarHBondContact O-N 2.88Å; D169-G171 VanDerWaalsContact O-N 3.12Å; D169-R183 WeakPolarHBondContact CA-O 3.5Å; D169-R183 WeakPolarHBondContact OD1-CB 3.33Å; D169-S186 VanDerWaalsContact CG-N 3.28Å; D169-S186 WeakPolarHBondContact OD1-CA 3.22Å; D169-S186 PolarHBondContact OD1-N 3.23Å; D169-S186 PolarHBondContact OD1-OG 3.49Å; D169-S186 PolarHBondContact OD2-N 3.18Å; D169-S186 VanDerWaalsContact OD2-N 3.16Å; D169-S186 PolarHBondContact OD2-OG 2.63Å
170I96Very high96.8Very high16 Ų1649 Ų498%0.08226%0.256CS..  trans-55117169.3-60.9163000108.6Y173 E178 V179 C182 R183 L184 H223I170-Y173 HydrophobicContact CB-CE2 4.2Å; I170-Y173 HydrophobicContact CD1-CE1 4.2Å; I170-Y173 HydrophobicContact CG2-CD1 4.13Å; I170-Y173 HydrophobicContact CG2-CD2 3.73Å; I170-Y173 HydrophobicContact CG2-CE1 4.13Å; I170-Y173 HydrophobicContact CG2-CE2 3.71Å; I170-Y173 HydrophobicContact CG2-CG 3.94Å; I170-E178 HydrophobicContact CG2-CB 4.44Å; I170-V179 HydrophobicContact CG2-CG2 4.32Å; I170-C182 HydrophobicContact CG1-CB 3.91Å; I170-R183 PolarHBondContact N-O 2.85Å; I170-L184 HydrophobicContact CD1-CB 4.46Å; I170-L184 HydrophobicContact CD1-CD1 4.46Å; I170-H223 WeakPolarHBondContact CD1-ND1 3.34Å
171G95.5Very high96.8Very high69 Ų6949.4 Ų49.471%0.71126%0.258SS*.SBendtrans-98.3-28.1176.200000112.3D169 E178D169-G171 PolarHBondContact O-N 2.88Å; D169-G171 VanDerWaalsContact O-N 3.12Å; G171-E178 PolarHBondContact N-OE2 3.26Å
172N95.7Very high96.8Very high68 Ų6849.4 Ų49.436%0.36426%0.258SS..  trans-132.299-177.8-178.716.5000111.7N174 D175 E178N172-N174 PolarHBondContact O-N 2.79Å; N172-N174 VanDerWaalsContact O-N 3.12Å; N172-N174 WeakPolarHBondContact OD1-CB 3.23Å; N172-N174 PolarHBondContact OD1-N 3.37Å; N172-D175 HydrophobicContact CB-CB 4.37Å; N172-D175 PolarHBondContact O-N 2.81Å; N172-E178 PolarHBondContact N-OE2 2.94Å
173Y94Very high96.8Very high92 Ų9249.4 Ų49.436%0.36126%0.258SS..THydrogen-bonded Turntrans-67.2-8.8176.3-77.3-94.8000114.5I170 D175 V179 H223I170-Y173 HydrophobicContact CB-CE2 4.2Å; I170-Y173 HydrophobicContact CD1-CE1 4.2Å; I170-Y173 HydrophobicContact CG2-CD1 4.13Å; I170-Y173 HydrophobicContact CG2-CD2 3.73Å; I170-Y173 HydrophobicContact CG2-CE1 4.13Å; I170-Y173 HydrophobicContact CG2-CE2 3.71Å; I170-Y173 HydrophobicContact CG2-CG 3.94Å; Y173-D175 VanDerWaalsContact C-N 3.32Å; Y173-V179 HydrophobicContact CD1-CG2 4.2Å; Y173-V179 WeakPolarHBondContact O-CG2 3.14Å; Y173-H223 AromaticContact CE1-CE1 3.97Å
174N96Very high96.7Very high116 Ų11650.6 Ų50.662%0.6226%0.264SS*.THydrogen-bonded Turntrans-85.9-4.2171.5-63.6-61.9000113.3N172 P176 A263N172-N174 PolarHBondContact O-N 2.79Å; N172-N174 VanDerWaalsContact O-N 3.12Å; N172-N174 WeakPolarHBondContact OD1-CB 3.23Å; N172-N174 PolarHBondContact OD1-N 3.37Å; N174-P176 WeakPolarHBondContact O-CD 3.49Å; N174-A263 WeakPolarHBondContact O-CB 3.38Å
175D97.6Very high96.5Very high57 Ų5748.4 Ų48.431%0.30525%0.254SS..  trans-101.4104.1174.9-173.7-11.2000109.6N172 Y173 W177 E178 V179N172-D175 HydrophobicContact CB-CB 4.37Å; N172-D175 PolarHBondContact O-N 2.81Å; Y173-D175 VanDerWaalsContact C-N 3.32Å; D175-W177 PolarHBondContact O-N 3.32Å; D175-W177 VanDerWaalsContact O-N 3.11Å; D175-W177 VanDerWaalsContact OD1-CB 3.28Å; D175-W177 WeakPolarHBondContact OD1-CB 3.28Å; D175-W177 PolarHBondContact OD1-N 2.66Å; D175-E178 HydrophobicContact CB-CB 4.21Å; D175-E178 HydrophobicContact CB-CG 4.16Å; D175-E178 PolarHBondContact O-N 3.47Å; D175-V179 WeakPolarHBondContact O-CG2 3.46Å; D175-V179 PolarHBondContact O-N 3.07Å
176P97.1Very high96.4Very high51 Ų5147 Ų4733%0.33125%0.25SC..Hα-helixtrans-56.8-26.8177.9-25.735.3000113.7N174 R180 A263 I264N174-P176 WeakPolarHBondContact O-CD 3.49Å; P176-R180 WeakPolarHBondContact O-CB 3.19Å; P176-R180 WeakPolarHBondContact O-CG 3.46Å; P176-R180 PolarHBondContact O-N 3.43Å; P176-A263 HydrophobicContact CG-CB 4.06Å; P176-I264 HydrophobicContact CB-CD1 4.44Å; P176-I264 HydrophobicContact CB-CG1 4.07Å; P176-I264 HydrophobicContact CG-CG1 4.43Å
177W97.8Very high96.3Very high100 Ų10047.8 Ų47.838%0.37925%0.254SS..Hα-helixtrans-68.2-45.6175.4-178.689.8000110.8I165 C166 D175 R180 N181I165-W177 HydrophobicContact CG2-CH2 4.35Å; I165-W177 HydrophobicContact CG2-CZ2 3.68Å; C166-W177 HydrophobicContact CB-CH2 3.96Å; C166-W177 HydrophobicContact CB-CZ3 4.4Å; D175-W177 PolarHBondContact O-N 3.32Å; D175-W177 VanDerWaalsContact O-N 3.11Å; D175-W177 VanDerWaalsContact OD1-CB 3.28Å; D175-W177 WeakPolarHBondContact OD1-CB 3.28Å; D175-W177 PolarHBondContact OD1-N 2.66Å; W177-R180 PolarHBondContact O-N 3.09Å; W177-N181 HydrophobicContact CZ2-CB 4.47Å; W177-N181 WeakPolarHBondContact O-CB 3.46Å; W177-N181 PolarHBondContact O-N 2.88Å; W177-N181 VanDerWaalsContact O-N 3.14Å; W177-N181 PolarHBondContact O-ND2 2.78Å
178E98Very high96.5Very high26 Ų2644.9 Ų44.912%0.12124%0.238CC..Hα-helixtrans-64.6-45.7175.8-70.9-159.6173.600111R168 I170 G171 N172 D175 R180 N181 C182R168-E178 IonicContact CZ-OE1 2.78Å; R168-E178 IonicContact NE-OE1 3.57Å; R168-E178 IonicContact NH2-OE1 2.74Å; R168-E178 PolarHBondContact NH2-OE1 3.39Å; I170-E178 HydrophobicContact CG2-CB 4.44Å; G171-E178 PolarHBondContact N-OE2 3.26Å; N172-E178 PolarHBondContact N-OE2 2.94Å; D175-E178 HydrophobicContact CB-CB 4.21Å; D175-E178 HydrophobicContact CB-CG 4.16Å; D175-E178 PolarHBondContact O-N 3.47Å; E178-R180 PolarHBondContact O-N 2.93Å; E178-R180 VanDerWaalsContact O-N 3.12Å; E178-N181 PolarHBondContact O-N 2.61Å; E178-C182 VanDerWaalsContact O-CB 3.23Å; E178-C182 WeakPolarHBondContact O-CB 3.5Å; E178-C182 PolarHBondContact O-N 3.17Å
179V97.9Very high96.6Very high0 Ų039.9 Ų39.90%022%0.219CC..Hα-helixtrans-59-29.9-176.6177.50000112.5I170 Y173 D175 K222 H223 I264I170-V179 HydrophobicContact CG2-CG2 4.32Å; Y173-V179 HydrophobicContact CD1-CG2 4.2Å; Y173-V179 WeakPolarHBondContact O-CG2 3.14Å; D175-V179 WeakPolarHBondContact O-CG2 3.46Å; D175-V179 PolarHBondContact O-N 3.07Å; V179-K222 HydrophobicContact CG1-CG 4.26Å; V179-H223 WeakPolarHBondContact O-CA 3.23Å; V179-H223 PolarHBondContact O-ND1 2.84Å; V179-I264 HydrophobicContact CB-CD1 3.8Å; V179-I264 HydrophobicContact CG1-CD1 3.42Å; V179-I264 VanDerWaalsContact CG1-CD1 3.42Å
180R97.9Very high96.6Very high22 Ų2237.6 Ų37.68%0.08321%0.207CC..Hα-helixtrans-103-5.9-177-67.6178.8170.3150.72.7116.3P176 W177 E178 H223 M224 Y225 I264 E268 Y269P176-R180 WeakPolarHBondContact O-CB 3.19Å; P176-R180 WeakPolarHBondContact O-CG 3.46Å; P176-R180 PolarHBondContact O-N 3.43Å; W177-R180 PolarHBondContact O-N 3.09Å; E178-R180 PolarHBondContact O-N 2.93Å; E178-R180 VanDerWaalsContact O-N 3.12Å; R180-H223 VanDerWaalsContact CA-O 3.27Å; R180-H223 WeakPolarHBondContact CA-O 2.69Å; R180-M224 PolarHBondContact NE-O 3.12Å; R180-Y225 HydrophobicContact CB-CD2 4Å; R180-Y225 HydrophobicContact CB-CE1 4.47Å; R180-Y225 HydrophobicContact CB-CE2 3.64Å; R180-I264 HydrophobicContact CG-CD1 3.91Å; R180-E268 IonicContact CZ-OE2 3.79Å; R180-E268 IonicContact NH1-OE2 3.67Å; R180-E268 PolarHBondContact NH1-OE2 3.03Å; R180-E268 IonicContact NH2-OE2 3.76Å; R180-E268 PolarHBondContact NH2-OE2 3.03Å; R180-Y269 PolarHBondContact NE-OH 3.45Å; R180-Y269 PolarHBondContact NH2-OH 3.49Å
181N97.8Very high96.8Very high14 Ų1438.2 Ų38.28%0.07521%0.21CC..Hα-helixtrans-129.5-19.4-177.4-63.1-81.6000113.7N162 I165 C166 W177 E178 Y225N162-N181 WeakPolarHBondContact CB-O 3.47Å; I165-N181 HydrophobicContact CG2-CB 4.03Å; C166-N181 HydrophobicContact CB-CB 4.49Å; C166-N181 WeakPolarHBondContact CB-O 3.4Å; W177-N181 HydrophobicContact CZ2-CB 4.47Å; W177-N181 WeakPolarHBondContact O-CB 3.46Å; W177-N181 PolarHBondContact O-N 2.88Å; W177-N181 VanDerWaalsContact O-N 3.14Å; W177-N181 PolarHBondContact O-ND2 2.78Å; E178-N181 PolarHBondContact O-N 2.61Å; N181-Y225 PolarHBondContact ND2-OH 3.37Å
182C98.3Very high96.9Very high0 Ų035.2 Ų35.20%018%0.177CC..SBendtrans-99.6159.9-179.4-58.10000110.8C166 I170 E178 L184C166-C182 HydrophobicContact CB-CB 3.99Å; C166-C182 WeakPolarHBondContact CB-SG 3.14Å; C166-C182 VanDerWaalsContact SG-CA 3.55Å; C166-C182 WeakPolarHBondContact SG-CB 3.32Å; C166-C182 CovalentContact SG-SG 2.03Å; C166-C182 PolarHBondContact SG-SG 2.94Å; I170-C182 HydrophobicContact CG1-CB 3.91Å; E178-C182 VanDerWaalsContact O-CB 3.23Å; E178-C182 WeakPolarHBondContact O-CB 3.5Å; E178-C182 PolarHBondContact O-N 3.17Å; C182-L184 PolarHBondContact O-N 2.93Å
183R97.5Very high97Very high11 Ų1135.2 Ų35.24%0.04218%0.182CC..BIsolated β-bridgetrans-65129.6-175-61.7-173.1179.4130.5-2.3112.3D163 N167 R168 D169 I170 V185 L187 D189D163-R183 IonicContact OD1-CZ 3.8Å; D163-R183 IonicContact OD1-NE 3.58Å; D163-R183 IonicContact OD1-NH2 3.6Å; D163-R183 PolarHBondContact OD1-NH2 2.94Å; D163-R183 IonicContact OD2-CZ 3.69Å; D163-R183 IonicContact OD2-NH2 2.74Å; D163-R183 PolarHBondContact OD2-NH2 3.47Å; N167-R183 VanDerWaalsContact OD1-CZ 3.28Å; N167-R183 PolarHBondContact OD1-NH1 3.48Å; N167-R183 PolarHBondContact OD1-NH2 3.21Å; N167-R183 VanDerWaalsContact OD1-NH2 3.1Å; R168-R183 PolarHBondContact O-N 3Å; D169-R183 WeakPolarHBondContact CA-O 3.5Å; D169-R183 WeakPolarHBondContact OD1-CB 3.33Å; I170-R183 PolarHBondContact N-O 2.85Å; R183-V185 PolarHBondContact O-N 3.14Å; R183-L187 VanDerWaalsContact CB-O 3.3Å; R183-L187 WeakPolarHBondContact CB-O 3.36Å; R183-L187 WeakPolarHBondContact CD-O 3.19Å; R183-L187 WeakPolarHBondContact CG-O 3.33Å; R183-D189 HydrophobicContact CG-CB 4.39Å
184L95Very high97.2Very high29 Ų2933.5 Ų33.515%0.15218%0.175CC..SBendtrans-74.6103.2164.9176.761.1000108.8I170 C182 S186 L187 A220I170-L184 HydrophobicContact CD1-CB 4.46Å; I170-L184 HydrophobicContact CD1-CD1 4.46Å; C182-L184 PolarHBondContact O-N 2.93Å; L184-S186 PolarHBondContact O-N 2.87Å; L184-L187 VanDerWaalsContact O-CB 3.24Å; L184-L187 WeakPolarHBondContact O-CB 3.27Å; L184-L187 WeakPolarHBondContact O-CD1 3.41Å; L184-L187 WeakPolarHBondContact O-CG 3.45Å; L184-L187 PolarHBondContact O-N 2.66Å; L184-L187 VanDerWaalsContact O-N 3.11Å; L184-A220 HydrophobicContact CD2-CB 4.03Å
185V91.6Very high97.3Very high59 Ų5931.1 Ų31.136%0.35817%0.166SC..THydrogen-bonded Turntrans52.851.8175.1-157.50000112.6R183 L187 F377R183-V185 PolarHBondContact O-N 3.14Å; V185-L187 PolarHBondContact O-N 2.66Å; V185-L187 VanDerWaalsContact O-N 3.16Å; V185-F377 HydrophobicContact CG1-CD2 4.12Å; V185-F377 HydrophobicContact CG1-CE2 3.34Å; V185-F377 HydrophobicContact CG1-CZ 3.66Å
186S94.8Very high97.3Very high34 Ų3432.6 Ų32.624%0.23817%0.171CC..THydrogen-bonded Turntrans63.213.7179.8-61.10000115.9A129 A130 D169 L184A129-S186 CarbonylContact C-O 3.56Å; A129-S186 WeakPolarHBondContact CA-O 3.21Å; A130-S186 WeakPolarHBondContact CB-O 3.26Å; A130-S186 PolarHBondContact N-O 3.16Å; D169-S186 VanDerWaalsContact CG-N 3.28Å; D169-S186 WeakPolarHBondContact OD1-CA 3.22Å; D169-S186 PolarHBondContact OD1-N 3.23Å; D169-S186 PolarHBondContact OD1-OG 3.49Å; D169-S186 PolarHBondContact OD2-N 3.18Å; D169-S186 VanDerWaalsContact OD2-N 3.16Å; D169-S186 PolarHBondContact OD2-OG 2.63Å; L184-S186 PolarHBondContact O-N 2.87Å
187L96.4Very high97.4Very high19 Ų1930.1 Ų30.110%0.09916%0.155CC..EExtended strand (participates in β ladder)trans-78.1136.4174.4-58.3170.9000110.7Q88 H126 A129 R183 L184 V185 D189Q88-L187 HydrophobicContact CG-CD2 3.64Å; H126-L187 HydrophobicContact CB-CB 3.84Å; H126-L187 WeakPolarHBondContact NE2-CD1 3.38Å; A129-L187 HydrophobicContact CB-CD2 4.37Å; R183-L187 VanDerWaalsContact CB-O 3.3Å; R183-L187 WeakPolarHBondContact CB-O 3.36Å; R183-L187 WeakPolarHBondContact CD-O 3.19Å; R183-L187 WeakPolarHBondContact CG-O 3.33Å; L184-L187 VanDerWaalsContact O-CB 3.24Å; L184-L187 WeakPolarHBondContact O-CB 3.27Å; L184-L187 WeakPolarHBondContact O-CD1 3.41Å; L184-L187 WeakPolarHBondContact O-CG 3.45Å; L184-L187 PolarHBondContact O-N 2.66Å; L184-L187 VanDerWaalsContact O-N 3.11Å; V185-L187 PolarHBondContact O-N 2.66Å; V185-L187 VanDerWaalsContact O-N 3.16Å; L187-D189 PolarHBondContact O-N 3.04Å
188M97.6Very high97.4Very high0 Ų025.7 Ų25.70%014%0.139CC..EExtended strand (participates in β ladder)trans-65.1107.9-177.9-69.5-51.9-5800110.8H126 M127 T128 A130 E149 F161H126-M188 CarbonylContact C-O 3.54Å; H126-M188 WeakPolarHBondContact CA-O 3.48Å; H126-M188 VanDerWaalsContact CB-O 3.29Å; H126-M188 WeakPolarHBondContact CB-O 3.13Å; M127-M188 HydrophobicContact CB-CB 4.29Å; M127-M188 PolarHBondContact N-O 2.64Å; T128-M188 WeakPolarHBondContact O-CB 3.36Å; T128-M188 VanDerWaalsContact O-CG 3.24Å; T128-M188 WeakPolarHBondContact O-CG 3.33Å; T128-M188 PolarHBondContact O-N 3.03Å; A130-M188 HydrophobicContact CB-SD 3.49Å; A130-M188 WeakPolarHBondContact CB-SD 3.31Å; E149-M188 HydrophobicContact CG-CE 3.47Å; E149-M188 VanDerWaalsContact CG-CE 3.47Å; E149-M188 WeakPolarHBondContact OE1-CE 3.4Å; F161-M188 HydrophobicContact CB-CE 4.38Å; F161-M188 HydrophobicContact CD1-CB 3.77Å; F161-M188 HydrophobicContact CD1-CE 4.21Å; F161-M188 HydrophobicContact CE1-CB 3.66Å; F161-M188 HydrophobicContact CG-CE 4.17Å
189D98.4Very high97.4Very high3 Ų330 Ų302%0.01616%0.159CC..EExtended strand (participates in β ladder)trans-80.4118.2-170.8-167.768.4000111.7N125 F161 N162 R183 L187N125-D189 PolarHBondContact ND2-OD1 2.8Å; F161-D189 CarbonylContact C-O 3.56Å; F161-D189 VanDerWaalsContact CA-O 3.23Å; F161-D189 WeakPolarHBondContact CA-O 3.26Å; F161-D189 WeakPolarHBondContact CB-O 3.5Å; F161-D189 WeakPolarHBondContact CD1-O 3.32Å; N162-D189 HydrophobicContact CB-CB 4.46Å; N162-D189 PolarHBondContact N-O 3.32Å; N162-D189 PolarHBondContact ND2-OD2 2.73Å; R183-D189 HydrophobicContact CG-CB 4.39Å; L187-D189 PolarHBondContact O-N 3.04Å
190L98.6Very high97.4Very high3 Ų332.5 Ų32.52%0.01617%0.169CC..BIsolated β-bridgetrans-72.9137.2-176.4-73.6168.2000110.6I124 N125 M127 Y156 F161 N162 L192 V197I124-L190 WeakPolarHBondContact O-CD1 3.33Å; N125-L190 WeakPolarHBondContact O-CB 3.3Å; N125-L190 PolarHBondContact O-N 3.27Å; M127-L190 HydrophobicContact CG-CD1 4.21Å; M127-L190 HydrophobicContact CG-CD2 3.87Å; M127-L190 HydrophobicContact CG-CG 4.07Å; M127-L190 HydrophobicContact SD-CD1 4.19Å; Y156-L190 HydrophobicContact CD2-CD2 3.99Å; Y156-L190 HydrophobicContact CE1-CD2 4.4Å; Y156-L190 HydrophobicContact CE2-CD2 3.8Å; Y156-L190 HydrophobicContact CG-CD2 4.41Å; F161-L190 HydrophobicContact CD1-CD2 4.11Å; F161-L190 HydrophobicContact CE1-CD2 3.61Å; F161-L190 HydrophobicContact CE1-CG 4.27Å; F161-L190 HydrophobicContact CZ-CD2 4.04Å; N162-L190 PolarHBondContact ND2-O 3.19Å; L190-L192 VanDerWaalsContact C-N 3.26Å; L190-L192 HydrophobicContact CB-CD2 4Å; L190-L192 HydrophobicContact CB-CG 4.31Å; L190-L192 PolarHBondContact O-N 3.14Å; L190-V197 HydrophobicContact CB-CG1 4.23Å; L190-V197 HydrophobicContact CD2-CG1 4.23Å
191K98.3Very high97.5Very high30 Ų3031.4 Ų31.413%0.1317%0.165CC..  trans-80.273.3175.7-168.7166-166.5163.40110.8D160 N162 D164 S193 R194D160-K191 WeakPolarHBondContact O-CB 3.27Å; D160-K191 PolarHBondContact O-N 2.91Å; N162-K191 VanDerWaalsContact OD1-CG 3.28Å; N162-K191 WeakPolarHBondContact OD1-CG 3.48Å; D164-K191 IonicContact OD1-NZ 2.96Å; D164-K191 PolarHBondContact OD1-NZ 3.45Å; D164-K191 IonicContact OD2-NZ 3.54Å; D164-K191 PolarHBondContact OD2-NZ 2.7Å; K191-S193 WeakPolarHBondContact CG-OG 3.44Å; K191-S193 PolarHBondContact O-N 2.91Å; K191-S193 VanDerWaalsContact O-N 3.08Å; K191-R194 HydrophobicContact CD-CG 4.06Å; K191-R194 HydrophobicContact CG-CG 3.99Å; K191-R194 WeakPolarHBondContact O-CB 3.35Å; K191-R194 PolarHBondContact O-N 3.07Å
192L98.2Very high97.5Very high6 Ų630.9 Ų30.93%0.03116%0.163CC..THydrogen-bonded Turntrans-65-12.4-177-61.1-177.1000114L190 R194 V197 Q198 V201 M224 D228 I232L190-L192 VanDerWaalsContact C-N 3.26Å; L190-L192 HydrophobicContact CB-CD2 4Å; L190-L192 HydrophobicContact CB-CG 4.31Å; L190-L192 PolarHBondContact O-N 3.14Å; L192-R194 PolarHBondContact O-N 3.48Å; L192-V197 HydrophobicContact CD2-CG1 3.7Å; L192-Q198 WeakPolarHBondContact O-CG 3.25Å; L192-Q198 PolarHBondContact O-NE2 3.45Å; L192-V201 HydrophobicContact CD2-CG2 4.36Å; L192-M224 HydrophobicContact CD1-CB 4.19Å; L192-M224 HydrophobicContact CD1-CG 3.59Å; L192-M224 HydrophobicContact CD1-SD 3.22Å; L192-M224 WeakPolarHBondContact CD1-SD 3.44Å; L192-D228 HydrophobicContact CB-CB 3.8Å; L192-I232 HydrophobicContact CD1-CD1 4.46Å; L192-I232 HydrophobicContact CD2-CD1 4.28Å
193S97.5Very high97.5Very high67 Ų6734.7 Ų34.747%0.46919%0.189SC..THydrogen-bonded Turntrans-65.8-16.5169.172.80000113.1K191 D228K191-S193 WeakPolarHBondContact CG-OG 3.44Å; K191-S193 PolarHBondContact O-N 2.91Å; K191-S193 VanDerWaalsContact O-N 3.08Å; S193-D228 PolarHBondContact N-OD2 3.3Å
194R98.1Very high97.6Very high57 Ų5734.5 Ų34.522%0.21519%0.189CC..SBendtrans-85.1126.3177.3-76.7-17069.5157.64.7111.7E159 K191 L192 E196 V197 Q198E159-R194 WeakPolarHBondContact O-CD 3.43Å; E159-R194 PolarHBondContact O-NH1 2.85Å; E159-R194 IonicContact OE2-CZ 3.02Å; E159-R194 IonicContact OE2-NH1 3.8Å; E159-R194 PolarHBondContact OE2-NH1 3.25Å; E159-R194 IonicContact OE2-NH2 3.88Å; K191-R194 HydrophobicContact CD-CG 4.06Å; K191-R194 HydrophobicContact CG-CG 3.99Å; K191-R194 WeakPolarHBondContact O-CB 3.35Å; K191-R194 PolarHBondContact O-N 3.07Å; L192-R194 PolarHBondContact O-N 3.48Å; R194-E196 IonicContact CZ-OE2 2.77Å; R194-E196 IonicContact NE-OE2 3.49Å; R194-E196 PolarHBondContact NE-OE2 3.49Å; R194-E196 IonicContact NH2-OE2 2.79Å; R194-E196 PolarHBondContact NH2-OE2 2.78Å; R194-E196 PolarHBondContact O-N 3.13Å; R194-V197 HydrophobicContact CB-CB 4.36Å; R194-V197 HydrophobicContact CB-CG2 3.92Å; R194-V197 PolarHBondContact O-N 3.36Å; R194-V197 VanDerWaalsContact O-N 3.13Å; R194-Q198 WeakPolarHBondContact O-CG 3.01Å; R194-Q198 PolarHBondContact O-N 2.89Å; R194-Q198 VanDerWaalsContact O-N 3.12Å
195P98.2Very high97.8Very high65 Ų6533.1 Ų33.142%0.42218%0.182SC..Hα-helixtrans-55.8-34.9176.4-27.736.3000114.4V197 Q198 E199P195-V197 VanDerWaalsContact C-N 3.33Å; P195-V197 PolarHBondContact O-N 2.93Å; P195-Q198 PolarHBondContact O-N 3.36Å; P195-E199 WeakPolarHBondContact O-CB 3.45Å; P195-E199 PolarHBondContact O-N 3.07Å
196E98Very high98.1Very high88 Ų8831.4 Ų31.441%0.41117%0.17SC..Hα-helixtrans-67.8-34.3-179.6-58.482.8-175.500112.3R194 K200R194-E196 IonicContact CZ-OE2 2.77Å; R194-E196 IonicContact NE-OE2 3.49Å; R194-E196 PolarHBondContact NE-OE2 3.49Å; R194-E196 IonicContact NH2-OE2 2.79Å; R194-E196 PolarHBondContact NH2-OE2 2.78Å; R194-E196 PolarHBondContact O-N 3.13Å; E196-K200 WeakPolarHBondContact O-CG 3.03Å; E196-K200 PolarHBondContact O-N 2.72Å
197V98.5Very high98.3Very high0 Ų032.8 Ų32.80%017%0.173CC..Hα-helixtrans-70.8-45.9174.6-176.60000109.7Y156 D160 L190 L192 R194 P195 E199 K200 V201Y156-V197 HydrophobicContact CE1-CB 4.29Å; Y156-V197 HydrophobicContact CE1-CG1 3.95Å; Y156-V197 HydrophobicContact CE1-CG2 4.1Å; D160-V197 HydrophobicContact CB-CG2 3.87Å; L190-V197 HydrophobicContact CB-CG1 4.23Å; L190-V197 HydrophobicContact CD2-CG1 4.23Å; L192-V197 HydrophobicContact CD2-CG1 3.7Å; R194-V197 HydrophobicContact CB-CB 4.36Å; R194-V197 HydrophobicContact CB-CG2 3.92Å; R194-V197 PolarHBondContact O-N 3.36Å; R194-V197 VanDerWaalsContact O-N 3.13Å; P195-V197 VanDerWaalsContact C-N 3.33Å; P195-V197 PolarHBondContact O-N 2.93Å; V197-E199 VanDerWaalsContact C-N 3.27Å; V197-E199 PolarHBondContact O-N 3.15Å; V197-K200 PolarHBondContact O-N 3.15Å; V197-V201 WeakPolarHBondContact O-CG2 3.23Å; V197-V201 PolarHBondContact O-N 3.42Å
198Q98.5Very high98.5Very high7 Ų731.9 Ų31.93%0.03317%0.168CC..Hα-helixtrans-56.5-40.1175-63168.81.500112.2L192 R194 P195 A202 Q231 I232L192-Q198 WeakPolarHBondContact O-CG 3.25Å; L192-Q198 PolarHBondContact O-NE2 3.45Å; R194-Q198 WeakPolarHBondContact O-CG 3.01Å; R194-Q198 PolarHBondContact O-N 2.89Å; R194-Q198 VanDerWaalsContact O-N 3.12Å; P195-Q198 PolarHBondContact O-N 3.36Å; Q198-A202 VanDerWaalsContact O-CB 3.23Å; Q198-A202 WeakPolarHBondContact O-CB 3.25Å; Q198-A202 PolarHBondContact O-N 2.93Å; Q198-Q231 VanDerWaalsContact CD-CB 3.43Å; Q198-Q231 HydrophobicContact CG-CB 4.33Å; Q198-Q231 VanDerWaalsContact OE1-CB 3.27Å; Q198-I232 HydrophobicContact CB-CG1 3.97Å; Q198-I232 HydrophobicContact CG-CG1 4.09Å
199E98.4Very high98.5Very high116 Ų11631.9 Ų31.954%0.54217%0.168SC..Hα-helixtrans-67.5-42.8177.9-91.5176.1170.700112.9P195 V197 A202 S203P195-E199 WeakPolarHBondContact O-CB 3.45Å; P195-E199 PolarHBondContact O-N 3.07Å; V197-E199 VanDerWaalsContact C-N 3.27Å; V197-E199 PolarHBondContact O-N 3.15Å; E199-A202 PolarHBondContact O-N 3.44Å; E199-S203 VanDerWaalsContact O-CB 3.3Å; E199-S203 WeakPolarHBondContact O-CB 3.37Å; E199-S203 PolarHBondContact O-N 2.86Å
200K98.6Very high98.5Very high52 Ų5234.9 Ų34.923%0.22618%0.184CC..Hα-helixtrans-63.3-43176.1-73.7165.5177.11710111.2Y92 V154 P155 Y156 D160 E196 V197 S203 Y204Y92-K200 HydrophobicContact CE2-CB 4.41Å; V154-K200 HydrophobicContact CG2-CB 4.29Å; V154-K200 HydrophobicContact CG2-CD 3.99Å; V154-K200 HydrophobicContact CG2-CG 4.38Å; P155-K200 PolarHBondContact O-NZ 2.66Å; Y156-K200 HydrophobicContact CD1-CD 3.74Å; Y156-K200 VanDerWaalsContact CD1-NZ 3.35Å; Y156-K200 HydrophobicContact CE1-CB 4.14Å; Y156-K200 HydrophobicContact CE1-CD 3.21Å; Y156-K200 HydrophobicContact CE1-CG 4.33Å; Y156-K200 WeakPolarHBondContact OH-CB 3.13Å; D160-K200 IonicContact OD1-NZ 3.2Å; E196-K200 WeakPolarHBondContact O-CG 3.03Å; E196-K200 PolarHBondContact O-N 2.72Å; V197-K200 PolarHBondContact O-N 3.15Å; K200-S203 PolarHBondContact O-N 2.76Å; K200-Y204 PolarHBondContact O-N 3.34Å; K200-Y204 VanDerWaalsContact O-N 3.09Å
201V98.8Very high98.6Very high0 Ų036 Ų360%019%0.19CC..Hα-helixtrans-63.1-49174.2176.40000111.1Y92 I124 L192 V197 S203 Y204 L205 I232Y92-V201 WeakPolarHBondContact OH-CG2 3.45Å; I124-V201 HydrophobicContact CB-CG1 3.79Å; I124-V201 HydrophobicContact CB-CG2 4.45Å; I124-V201 HydrophobicContact CD1-CG1 4.09Å; I124-V201 HydrophobicContact CG2-CG1 3.56Å; L192-V201 HydrophobicContact CD2-CG2 4.36Å; V197-V201 WeakPolarHBondContact O-CG2 3.23Å; V197-V201 PolarHBondContact O-N 3.42Å; V201-S203 VanDerWaalsContact C-N 3.27Å; V201-S203 PolarHBondContact O-N 3.21Å; V201-Y204 WeakPolarHBondContact O-CB 3.49Å; V201-Y204 PolarHBondContact O-N 3.3Å; V201-Y204 VanDerWaalsContact O-N 3.13Å; V201-L205 HydrophobicContact CG1-CD1 4.12Å; V201-L205 HydrophobicContact CG1-CG 4.39Å; V201-L205 WeakPolarHBondContact O-CG 3.36Å; V201-L205 PolarHBondContact O-N 2.9Å; V201-I232 HydrophobicContact CB-CD1 4.28Å; V201-I232 HydrophobicContact CG1-CD1 3.99Å; V201-I232 HydrophobicContact CG1-CG1 4.43Å; V201-I232 HydrophobicContact CG1-CG2 3.85Å
202A98.8Very high98.6Very high3 Ų334.6 Ų34.63%0.02518%0.184CC..Hα-helixtrans-61.7-35.9178.600000111.9Q198 E199 L205 N206 I232 R235Q198-A202 VanDerWaalsContact O-CB 3.23Å; Q198-A202 WeakPolarHBondContact O-CB 3.25Å; Q198-A202 PolarHBondContact O-N 2.93Å; E199-A202 PolarHBondContact O-N 3.44Å; A202-L205 PolarHBondContact O-N 2.65Å; A202-N206 WeakPolarHBondContact O-CB 3.35Å; A202-N206 PolarHBondContact O-N 2.73Å; A202-N206 PolarHBondContact O-ND2 2.92Å; A202-N206 VanDerWaalsContact O-ND2 3.15Å; A202-I232 HydrophobicContact CB-CG2 4.38Å; A202-R235 HydrophobicContact CB-CB 3.7Å
203S98.7Very high98.6Very high79 Ų7934.3 Ų34.355%0.55218%0.183SC*.Hα-helixtrans-62.4-43.1174.2-174.40000111.6E199 K200 V201 N206 H207E199-S203 VanDerWaalsContact O-CB 3.3Å; E199-S203 WeakPolarHBondContact O-CB 3.37Å; E199-S203 PolarHBondContact O-N 2.86Å; K200-S203 PolarHBondContact O-N 2.76Å; V201-S203 VanDerWaalsContact C-N 3.27Å; V201-S203 PolarHBondContact O-N 3.21Å; S203-N206 PolarHBondContact O-N 2.75Å; S203-H207 PolarHBondContact O-N 2.74Å
204Y98.8Very high98.7Very high8 Ų831.1 Ų31.13%0.03116%0.16CC..Hα-helixtrans-61.7-49.8175.2163.4-125.3000112.1N70 Y92 L94 K200 V201 N206 H207 L208N70-Y204 HydrophobicContact CB-CE2 4.31Å; Y92-Y204 AromaticContact CD1-CD1 3.58Å; Y92-Y204 HydrophobicContact CD1-CD1 3.58Å; Y92-Y204 HydrophobicContact CD1-CD2 4.07Å; Y92-Y204 AromaticContact CD1-CE1 3.97Å; Y92-Y204 HydrophobicContact CD1-CE1 3.97Å; Y92-Y204 HydrophobicContact CD1-CE2 4.4Å; Y92-Y204 AromaticContact CD1-CG 3.62Å; Y92-Y204 HydrophobicContact CD1-CG 3.62Å; Y92-Y204 HydrophobicContact CD2-CG 4.25Å; Y92-Y204 AromaticContact CE1-CD1 3.91Å; Y92-Y204 HydrophobicContact CE1-CD1 3.91Å; Y92-Y204 HydrophobicContact CE1-CE1 4.34Å; Y92-Y204 HydrophobicContact CE1-CG 4.31Å; Y92-Y204 HydrophobicContact CG-CD1 4.06Å; Y92-Y204 AromaticContact CG-CD2 3.98Å; Y92-Y204 HydrophobicContact CG-CD2 3.98Å; Y92-Y204 AromaticContact CG-CG 3.61Å; Y92-Y204 HydrophobicContact CG-CG 3.61Å; L94-Y204 HydrophobicContact CD2-CE2 3.82Å; K200-Y204 PolarHBondContact O-N 3.34Å; K200-Y204 VanDerWaalsContact O-N 3.09Å; V201-Y204 WeakPolarHBondContact O-CB 3.49Å; V201-Y204 PolarHBondContact O-N 3.3Å; V201-Y204 VanDerWaalsContact O-N 3.13Å; Y204-N206 VanDerWaalsContact C-N 3.31Å; Y204-N206 PolarHBondContact O-N 2.99Å; Y204-H207 WeakPolarHBondContact O-CB 3.41Å; Y204-H207 PolarHBondContact O-N 2.91Å; Y204-L208 HydrophobicContact CD2-CD1 4.22Å; Y204-L208 HydrophobicContact CD2-CG 4.42Å; Y204-L208 HydrophobicContact CE1-CD1 4.18Å; Y204-L208 HydrophobicContact CE2-CD1 3.62Å; Y204-L208 HydrophobicContact CE2-CD2 4.49Å; Y204-L208 HydrophobicContact CE2-CG 4.05Å; Y204-L208 PolarHBondContact O-N 3.39Å; Y204-L208 VanDerWaalsContact O-N 3.15Å
205L98.9Very high98.7Very high0 Ų028.4 Ų28.40%015%0.15CC..Hα-helixtrans-64.8-36.3178.9-61.7179.7000111.9A122 V201 A202 L208 I209 F216 I232 L236A122-L205 HydrophobicContact CB-CD2 4.02Å; V201-L205 HydrophobicContact CG1-CD1 4.12Å; V201-L205 HydrophobicContact CG1-CG 4.39Å; V201-L205 WeakPolarHBondContact O-CG 3.36Å; V201-L205 PolarHBondContact O-N 2.9Å; A202-L205 PolarHBondContact O-N 2.65Å; L205-L208 HydrophobicContact CD2-CD1 4.47Å; L205-L208 WeakPolarHBondContact O-CB 3.44Å; L205-L208 PolarHBondContact O-N 2.91Å; L205-I209 WeakPolarHBondContact O-CG1 3.4Å; L205-I209 PolarHBondContact O-N 3.03Å; L205-F216 HydrophobicContact CB-CE1 4.49Å; L205-F216 HydrophobicContact CB-CE2 4.25Å; L205-F216 HydrophobicContact CB-CZ 4.02Å; L205-F216 HydrophobicContact CD2-CD1 3.76Å; L205-F216 HydrophobicContact CD2-CE1 3.72Å; L205-F216 HydrophobicContact CD2-CE2 4.46Å; L205-F216 HydrophobicContact CD2-CG 4.17Å; L205-F216 HydrophobicContact CD2-CZ 4.08Å; L205-F216 WeakPolarHBondContact O-CZ 3.45Å; L205-I232 HydrophobicContact CD1-CG2 3.88Å; L205-L236 HydrophobicContact CB-CD2 3.55Å; L205-L236 HydrophobicContact CD1-CD2 4.02Å; L205-L236 HydrophobicContact CG-CD2 4.44Å
206N98.9Very high98.7Very high22 Ų2225.3 Ų25.312%0.11813%0.13CC..Hα-helixtrans-67.1-35.5174.8-78.9-29.5000113A202 S203 Y204 L208 I209 D210 R235 L236 K237A202-N206 WeakPolarHBondContact O-CB 3.35Å; A202-N206 PolarHBondContact O-N 2.73Å; A202-N206 PolarHBondContact O-ND2 2.92Å; A202-N206 VanDerWaalsContact O-ND2 3.15Å; S203-N206 PolarHBondContact O-N 2.75Å; Y204-N206 VanDerWaalsContact C-N 3.31Å; Y204-N206 PolarHBondContact O-N 2.99Å; N206-L208 VanDerWaalsContact C-N 3.35Å; N206-I209 PolarHBondContact O-N 3.44Å; N206-D210 PolarHBondContact O-N 3.17Å; N206-R235 PolarHBondContact ND2-O 3.33Å; N206-L236 VanDerWaalsContact OD1-CA 3.27Å; N206-L236 WeakPolarHBondContact OD1-CA 3.46Å; N206-K237 HydrophobicContact CB-CD 4.06Å; N206-K237 HydrophobicContact CB-CG 4.35Å; N206-K237 WeakPolarHBondContact OD1-CG 3.4Å; N206-K237 PolarHBondContact OD1-N 3.2Å
207H98.9Very high98.8Very high63 Ų6321.2 Ų21.229%0.29211%0.111SC..Hα-helixtrans-60.9-45.6172.2-177.156.8000111E101 S203 Y204 I209 D210 L211E101-H207 IonicContact OE1-CE1 3.88Å; E101-H207 PolarHBondContact OE1-CE1 3.25Å; E101-H207 IonicContact OE1-NE2 2.88Å; E101-H207 PolarHBondContact OE1-NE2 2.03Å; E101-H207 IonicContact OE2-NE2 3.92Å; S203-H207 PolarHBondContact O-N 2.74Å; Y204-H207 WeakPolarHBondContact O-CB 3.41Å; Y204-H207 PolarHBondContact O-N 2.91Å; H207-I209 VanDerWaalsContact C-N 3.34Å; H207-I209 PolarHBondContact O-N 3.11Å; H207-D210 WeakPolarHBondContact O-CB 3.41Å; H207-D210 PolarHBondContact O-N 2.88Å; H207-D210 VanDerWaalsContact O-N 3.15Å; H207-L211 WeakPolarHBondContact O-CG 3.32Å; H207-L211 PolarHBondContact O-N 2.83Å
208L98.9Very high98.8Very high0 Ų021.2 Ų21.20%011%0.111CC..Hα-helixtrans-60.9-40.7174.4-68.2172.8000112.6P69 L94 F104 V120 Y204 L205 N206 D210 L211 G212 V213 F216P69-L208 HydrophobicContact CG-CD1 4.5Å; P69-L208 HydrophobicContact CG-CD2 4.16Å; L94-L208 HydrophobicContact CD1-CD2 3.79Å; L94-L208 HydrophobicContact CD2-CD2 3.83Å; F104-L208 HydrophobicContact CD1-CD2 4.46Å; F104-L208 HydrophobicContact CE1-CD2 3.5Å; F104-L208 VanDerWaalsContact CE1-CD2 3.5Å; F104-L208 HydrophobicContact CZ-CD2 4.01Å; V120-L208 HydrophobicContact CB-CD1 4.36Å; V120-L208 HydrophobicContact CG1-CD1 3.92Å; V120-L208 HydrophobicContact CG2-CD1 4.34Å; V120-L208 HydrophobicContact CG2-CD2 4.47Å; Y204-L208 HydrophobicContact CD2-CD1 4.22Å; Y204-L208 HydrophobicContact CD2-CG 4.42Å; Y204-L208 HydrophobicContact CE1-CD1 4.18Å; Y204-L208 HydrophobicContact CE2-CD1 3.62Å; Y204-L208 HydrophobicContact CE2-CD2 4.49Å; Y204-L208 HydrophobicContact CE2-CG 4.05Å; Y204-L208 PolarHBondContact O-N 3.39Å; Y204-L208 VanDerWaalsContact O-N 3.15Å; L205-L208 HydrophobicContact CD2-CD1 4.47Å; L205-L208 WeakPolarHBondContact O-CB 3.44Å; L205-L208 PolarHBondContact O-N 2.91Å; N206-L208 VanDerWaalsContact C-N 3.35Å; L208-D210 VanDerWaalsContact C-N 3.35Å; L208-L211 PolarHBondContact O-N 2.96Å; L208-G212 PolarHBondContact O-N 2.93Å; L208-V213 HydrophobicContact CB-CB 4.17Å; L208-V213 HydrophobicContact CB-CG2 3.97Å; L208-V213 HydrophobicContact CD2-CG2 4.32Å; L208-V213 VanDerWaalsContact O-CB 3.25Å; L208-V213 WeakPolarHBondContact O-CB 3.48Å; L208-V213 WeakPolarHBondContact O-CG2 3.34Å; L208-V213 PolarHBondContact O-N 3.06Å; L208-F216 HydrophobicContact CB-CE1 3.91Å; L208-F216 HydrophobicContact CB-CZ 4.09Å; L208-F216 HydrophobicContact CD1-CD1 4.5Å; L208-F216 HydrophobicContact CD1-CE1 3.7Å; L208-F216 HydrophobicContact CG-CE1 4.47Å
209I98.9Very high98.8Very high0 Ų021.5 Ų21.50%011%0.113CC..Hα-helixtrans-61-43.9173.7-70.7165.4000110.9L205 N206 H207 L211 G212 F216 L236 K237 K238 L239 N240 P250L205-I209 WeakPolarHBondContact O-CG1 3.4Å; L205-I209 PolarHBondContact O-N 3.03Å; N206-I209 PolarHBondContact O-N 3.44Å; H207-I209 VanDerWaalsContact C-N 3.34Å; H207-I209 PolarHBondContact O-N 3.11Å; I209-L211 VanDerWaalsContact C-N 3.25Å; I209-L211 PolarHBondContact O-N 3.29Å; I209-G212 PolarHBondContact O-N 3.2Å; I209-F216 HydrophobicContact CD1-CE2 4.11Å; I209-F216 HydrophobicContact CD1-CZ 4.4Å; I209-F216 HydrophobicContact CG1-CE2 4.01Å; I209-F216 HydrophobicContact CG1-CZ 3.93Å; I209-L236 HydrophobicContact CD1-CB 4.14Å; I209-L236 HydrophobicContact CD1-CD2 4.4Å; I209-K237 HydrophobicContact CG2-CB 4.25Å; I209-K238 WeakPolarHBondContact CG2-O 3.42Å; I209-L239 HydrophobicContact CG1-CD2 4.37Å; I209-L239 HydrophobicContact CG2-CD2 4.23Å; I209-N240 WeakPolarHBondContact O-CB 3.45Å; I209-P250 HydrophobicContact CD1-CB 4.45Å; I209-P250 HydrophobicContact CD1-CG 4.12Å
210D98.9Very high98.8Very high67 Ų6716.1 Ų16.136%0.3589%0.087SC..Hα-helixtrans-60.9-36.2178-66.9-34.7000111.2N206 H207 L208 G212 K237 N240N206-D210 PolarHBondContact O-N 3.17Å; H207-D210 WeakPolarHBondContact O-CB 3.41Å; H207-D210 PolarHBondContact O-N 2.88Å; H207-D210 VanDerWaalsContact O-N 3.15Å; L208-D210 VanDerWaalsContact C-N 3.35Å; D210-G212 PolarHBondContact O-N 3.19Å; D210-K237 WeakPolarHBondContact OD1-CD 3.2Å; D210-K237 IonicContact OD1-NZ 3.46Å; D210-K237 PolarHBondContact OD1-NZ 3.09Å; D210-K237 IonicContact OD2-NZ 3.45Å; D210-K237 PolarHBondContact OD2-NZ 2.87Å; D210-N240 PolarHBondContact O-ND2 3.03Å
211L98.9Very high98.8Very high27 Ų2713.6 Ų13.614%0.1418%0.077CC..Hα-helixtrans-71.6-12.8174.6-63.2-179.2000114L94 E101 F104 T105 I108 H207 L208 I209L94-L211 HydrophobicContact CD1-CD1 3.46Å; L94-L211 VanDerWaalsContact CD1-CD1 3.46Å; E101-L211 HydrophobicContact CG-CD1 4.4Å; F104-L211 HydrophobicContact CD1-CD1 4Å; F104-L211 HydrophobicContact CE1-CD1 4.3Å; T105-L211 HydrophobicContact CG2-CD2 4.21Å; I108-L211 HydrophobicContact CD1-CB 3.99Å; I108-L211 VanDerWaalsContact CG2-O 3.28Å; I108-L211 WeakPolarHBondContact CG2-O 3.49Å; H207-L211 WeakPolarHBondContact O-CG 3.32Å; H207-L211 PolarHBondContact O-N 2.83Å; L208-L211 PolarHBondContact O-N 2.96Å; I209-L211 VanDerWaalsContact C-N 3.25Å; I209-L211 PolarHBondContact O-N 3.29Å
212G98.8Very high98.7Very high0 Ų014 Ų140%08%0.078CC..THydrogen-bonded Turntrans105.813.4177.400000115.4H112 L208 I209 D210 F243 F244H112-G212 PolarHBondContact NE2-O 2.96Å; L208-G212 PolarHBondContact O-N 2.93Å; I209-G212 PolarHBondContact O-N 3.2Å; D210-G212 PolarHBondContact O-N 3.19Å; G212-F243 VanDerWaalsContact CA-CD2 3.49Å; G212-F244 WeakPolarHBondContact O-CE2 3.4Å
213V98.9Very high98.7Very high0 Ų014.3 Ų14.30%08%0.079CC..  trans-61.2134.9171.9171.50000110.3F104 I108 I118 V120 L208 G215 F216 L239F104-V213 HydrophobicContact CE1-CG2 4.05Å; F104-V213 HydrophobicContact CZ-CG2 3.92Å; I108-V213 HydrophobicContact CD1-CG2 3.72Å; I118-V213 HydrophobicContact CG2-CG2 4.49Å; V120-V213 HydrophobicContact CB-CG1 4.23Å; V120-V213 HydrophobicContact CG2-CG1 3.82Å; V120-V213 HydrophobicContact CG2-CG2 3.82Å; L208-V213 HydrophobicContact CB-CB 4.17Å; L208-V213 HydrophobicContact CB-CG2 3.97Å; L208-V213 HydrophobicContact CD2-CG2 4.32Å; L208-V213 VanDerWaalsContact O-CB 3.25Å; L208-V213 WeakPolarHBondContact O-CB 3.48Å; L208-V213 WeakPolarHBondContact O-CG2 3.34Å; L208-V213 PolarHBondContact O-N 3.06Å; V213-G215 WeakPolarHBondContact CG1-O 3.42Å; V213-F216 HydrophobicContact CG1-CD1 4.43Å; V213-F216 HydrophobicContact CG1-CE1 3.85Å; V213-F216 HydrophobicContact CG1-CZ 4.15Å; V213-L239 WeakPolarHBondContact O-CD2 3.32Å
214A98.8Very high98.7Very high0 Ų010.8 Ų10.80%05%0.054CC..  trans-85.2-20.3-176.400000113.8K117 I118 F244 P250 F251K117-A214 HydrophobicContact CB-CB 3.78Å; K117-A214 HydrophobicContact CG-CB 4.46Å; I118-A214 WeakPolarHBondContact O-CB 3.47Å; I118-A214 PolarHBondContact O-N 3.4Å; A214-F244 VanDerWaalsContact CA-CZ 3.5Å; A214-F244 HydrophobicContact CB-CE1 3.79Å; A214-F244 HydrophobicContact CB-CZ 3.5Å; A214-F244 VanDerWaalsContact CB-CZ 3.5Å; A214-P250 CarbonylContact O-C 3.27Å; A214-P250 VanDerWaalsContact O-CA 3.31Å; A214-P250 WeakPolarHBondContact O-CA 3.41Å; A214-F251 PolarHBondContact O-N 3.5Å
215G98.8Very high98.7Very high0 Ų013.5 Ų13.50%07%0.065CC..EExtended strand (participates in β ladder)trans174.2-176.4-174.800000114.7I119 V120 V213 F251I119-G215 WeakPolarHBondContact CA-O 3.41Å; V120-G215 PolarHBondContact N-O 2.92Å; V213-G215 WeakPolarHBondContact CG1-O 3.42Å; G215-F251 CarbonylContact C-O 3.51Å; G215-F251 WeakPolarHBondContact CA-O 3.5Å
216F98.9Very high98.7Very high0 Ų014.1 Ų14.10%07%0.069CC..EExtended strand (participates in β ladder)trans-137.1133-172.1-52.7-74000112V120 A122 L205 L208 I209 V213 I218 P250 F251 I252 V253V120-F216 HydrophobicContact CB-CD1 3.92Å; V120-F216 HydrophobicContact CB-CE1 4.21Å; V120-F216 HydrophobicContact CG1-CD1 4.31Å; V120-F216 CarbonylContact O-C 3.57Å; V120-F216 VanDerWaalsContact O-CA 3.24Å; V120-F216 WeakPolarHBondContact O-CA 3.36Å; A122-F216 HydrophobicContact CB-CB 4.28Å; A122-F216 HydrophobicContact CB-CD1 4.26Å; L205-F216 HydrophobicContact CB-CE1 4.49Å; L205-F216 HydrophobicContact CB-CE2 4.25Å; L205-F216 HydrophobicContact CB-CZ 4.02Å; L205-F216 HydrophobicContact CD2-CD1 3.76Å; L205-F216 HydrophobicContact CD2-CE1 3.72Å; L205-F216 HydrophobicContact CD2-CE2 4.46Å; L205-F216 HydrophobicContact CD2-CG 4.17Å; L205-F216 HydrophobicContact CD2-CZ 4.08Å; L205-F216 WeakPolarHBondContact O-CZ 3.45Å; L208-F216 HydrophobicContact CB-CE1 3.91Å; L208-F216 HydrophobicContact CB-CZ 4.09Å; L208-F216 HydrophobicContact CD1-CD1 4.5Å; L208-F216 HydrophobicContact CD1-CE1 3.7Å; L208-F216 HydrophobicContact CG-CE1 4.47Å; I209-F216 HydrophobicContact CD1-CE2 4.11Å; I209-F216 HydrophobicContact CD1-CZ 4.4Å; I209-F216 HydrophobicContact CG1-CE2 4.01Å; I209-F216 HydrophobicContact CG1-CZ 3.93Å; V213-F216 HydrophobicContact CG1-CD1 4.43Å; V213-F216 HydrophobicContact CG1-CE1 3.85Å; V213-F216 HydrophobicContact CG1-CZ 4.15Å; F216-I218 HydrophobicContact CB-CD1 3.82Å; F216-P250 HydrophobicContact CD2-CB 4.14Å; F216-P250 HydrophobicContact CE2-CB 3.94Å; F216-P250 HydrophobicContact CE2-CG 4.42Å; F216-F251 PolarHBondContact N-O 3.04Å; F216-I252 HydrophobicContact CB-CD1 4.1Å; F216-I252 HydrophobicContact CD2-CD1 3.77Å; F216-I252 HydrophobicContact CG-CD1 4.44Å; F216-I252 WeakPolarHBondContact O-CA 3.26Å; F216-V253 PolarHBondContact O-N 3.45Å
217R98.8Very high98.6Very high2 Ų218.8 Ų18.81%0.0089%0.09CC..EExtended strand (participates in β ladder)trans-88.3113.9156.3179.3-96.1-173.8179.7-1.6107V120 D121 A122 D219 V253 E255V120-R217 PolarHBondContact O-N 2.79Å; D121-R217 VanDerWaalsContact CG-NH1 3.34Å; D121-R217 WeakPolarHBondContact OD1-CD 3.42Å; D121-R217 IonicContact OD1-CZ 3.83Å; D121-R217 IonicContact OD1-NE 3.54Å; D121-R217 IonicContact OD1-NH1 2.65Å; D121-R217 PolarHBondContact OD1-NH1 2.69Å; D121-R217 IonicContact OD2-CZ 2.74Å; D121-R217 IonicContact OD2-NH1 2.87Å; D121-R217 PolarHBondContact OD2-NH1 3.29Å; A122-R217 PolarHBondContact N-O 3.03Å; R217-D219 IonicContact CZ-OD1 3.49Å; R217-D219 VanDerWaalsContact NH1-CB 3.32Å; R217-D219 IonicContact NH1-OD1 2.75Å; R217-D219 PolarHBondContact NH1-OD1 3.19Å; R217-D219 IonicContact NH2-OD1 3.14Å; R217-D219 PolarHBondContact NH2-OD1 2.96Å; R217-D219 PolarHBondContact O-N 3.16Å; R217-V253 CarbonylContact C-O 3.59Å; R217-V253 VanDerWaalsContact CA-O 3.25Å; R217-V253 WeakPolarHBondContact CA-O 3.49Å; R217-V253 HydrophobicContact CB-CG1 3.65Å; R217-V253 HydrophobicContact CG-CG1 3.89Å; R217-E255 IonicContact NH2-OE1 2.73Å; R217-E255 PolarHBondContact NH2-OE1 3.3Å; R217-E255 IonicContact NH2-OE2 3.34Å
218I98.9Very high98.6Very high0 Ų017 Ų170%08%0.082CC..EExtended strand (participates in β ladder)trans-81107.3179.5-53.7-56.8000108.2A122 I124 F216 A221 M224 I252 V253 E255A122-I218 HydrophobicContact CB-CD1 4.22Å; I124-I218 HydrophobicContact CD1-CD1 4.2Å; I124-I218 HydrophobicContact CD1-CG2 3.89Å; I124-I218 HydrophobicContact CG1-CG2 3.99Å; F216-I218 HydrophobicContact CB-CD1 3.82Å; I218-A221 HydrophobicContact CB-CB 4.3Å; I218-A221 HydrophobicContact CG2-CB 4.01Å; I218-M224 HydrophobicContact CG2-CE 3.33Å; I218-I252 HydrophobicContact CG1-CG2 3.94Å; I218-V253 PolarHBondContact N-O 3.2Å; I218-E255 VanDerWaalsContact O-CB 3.27Å; I218-E255 WeakPolarHBondContact O-CB 3.44Å; I218-E255 PolarHBondContact O-N 3.44Å
219D98.7Very high98.6Very high13 Ų1317 Ų177%0.078%0.083CC..THydrogen-bonded Turntrans-64.4142.5176-178.272.6000111.1A122 V123 H126 R217 A221 M224A122-D219 WeakPolarHBondContact O-CB 3.41Å; A122-D219 PolarHBondContact O-N 3.43Å; V123-D219 HydrophobicContact CB-CB 4.49Å; V123-D219 HydrophobicContact CG2-CB 3.98Å; H126-D219 IonicContact CE1-OD2 2.77Å; R217-D219 IonicContact CZ-OD1 3.49Å; R217-D219 VanDerWaalsContact NH1-CB 3.32Å; R217-D219 IonicContact NH1-OD1 2.75Å; R217-D219 PolarHBondContact NH1-OD1 3.19Å; R217-D219 IonicContact NH2-OD1 3.14Å; R217-D219 PolarHBondContact NH2-OD1 2.96Å; R217-D219 PolarHBondContact O-N 3.16Å; D219-A221 PolarHBondContact O-N 3.17Å; D219-A221 VanDerWaalsContact O-N 3.1Å; D219-M224 WeakPolarHBondContact O-CE 3.39Å
220A97.9Very high98.5Very high2 Ų220.7 Ų20.72%0.01710%0.097CC..THydrogen-bonded Turntrans53.232.2176.800000113.7N125 L184 K222 H223 E255N125-A220 HydrophobicContact CB-CB 4.07Å; L184-A220 HydrophobicContact CD2-CB 4.03Å; A220-K222 PolarHBondContact O-N 3.31Å; A220-K222 VanDerWaalsContact O-N 3.14Å; A220-H223 HydrophobicContact CB-CB 4.39Å; A220-H223 WeakPolarHBondContact O-CA 3.45Å; A220-H223 VanDerWaalsContact O-CB 3.31Å; A220-H223 WeakPolarHBondContact O-CB 3.42Å; A220-H223 PolarHBondContact O-N 2.98Å; A220-E255 VanDerWaalsContact CA-OE2 3.3Å; A220-E255 WeakPolarHBondContact CA-OE2 3.42Å; A220-E255 PolarHBondContact N-OE2 3.37Å; A220-E255 VanDerWaalsContact N-OE2 3.08Å
221A98.7Very high98.5Very high0 Ų020.2 Ų20.20%09%0.092CC..G310 helixtrans-58.3-31.4-177.900000113.1I218 D219 H223 M224 I229 N254 E255 V256 Y269I218-A221 HydrophobicContact CB-CB 4.3Å; I218-A221 HydrophobicContact CG2-CB 4.01Å; D219-A221 PolarHBondContact O-N 3.17Å; D219-A221 VanDerWaalsContact O-N 3.1Å; A221-H223 PolarHBondContact O-N 3.33Å; A221-H223 VanDerWaalsContact O-N 3.12Å; A221-M224 HydrophobicContact CB-CE 4.28Å; A221-M224 PolarHBondContact O-N 3.33Å; A221-I229 HydrophobicContact CB-CD1 4.1Å; A221-N254 HydrophobicContact CB-CB 3.66Å; A221-E255 WeakPolarHBondContact CA-O 3.28Å; A221-E255 WeakPolarHBondContact CB-O 3.38Å; A221-E255 PolarHBondContact N-O 2.68Å; A221-V256 HydrophobicContact CB-CG2 4.33Å; A221-Y269 WeakPolarHBondContact O-CE1 3.16Å; A221-Y269 PolarHBondContact O-OH 3.32Å
222K97.9Very high98.5Very high8 Ų819 Ų194%0.0359%0.086CC..G310 helixtrans-51.7-30.3170-174.6176.9179.6174.50113.6V179 A220 E255 V256 I257 E262 I264 Y269V179-K222 HydrophobicContact CG1-CG 4.26Å; A220-K222 PolarHBondContact O-N 3.31Å; A220-K222 VanDerWaalsContact O-N 3.14Å; K222-E255 PolarHBondContact N-O 3.39Å; K222-V256 HydrophobicContact CB-CG1 4.26Å; K222-V256 HydrophobicContact CG-CG1 4.46Å; K222-I257 HydrophobicContact CD-CB 4.26Å; K222-I257 WeakPolarHBondContact CD-O 3.34Å; K222-I257 WeakPolarHBondContact CE-O 3.5Å; K222-I257 PolarHBondContact NZ-O 2.99Å; K222-E262 IonicContact NZ-OE2 3.13Å; K222-E262 PolarHBondContact NZ-OE2 2.93Å; K222-I264 HydrophobicContact CG-CB 4.18Å; K222-I264 HydrophobicContact CG-CD1 4.2Å; K222-I264 HydrophobicContact CG-CG2 4.09Å; K222-I264 WeakPolarHBondContact O-CD1 3.48Å; K222-Y269 PolarHBondContact O-OH 3.03Å
223H98.4Very high98.4Very high10 Ų1019 Ų195%0.0469%0.086CC..G310 helixtrans-89.91.6-176.4-62.9-78.2000113.7N125 I170 Y173 V179 R180 A220 A221N125-H223 VanDerWaalsContact OD1-CB 3.24Å; N125-H223 WeakPolarHBondContact OD1-CB 3.47Å; N125-H223 PolarHBondContact OD1-O 3.03Å; N125-H223 VanDerWaalsContact OD1-O 3.05Å; I170-H223 WeakPolarHBondContact CD1-ND1 3.34Å; Y173-H223 AromaticContact CE1-CE1 3.97Å; V179-H223 WeakPolarHBondContact O-CA 3.23Å; V179-H223 PolarHBondContact O-ND1 2.84Å; R180-H223 VanDerWaalsContact CA-O 3.27Å; R180-H223 WeakPolarHBondContact CA-O 2.69Å; A220-H223 HydrophobicContact CB-CB 4.39Å; A220-H223 WeakPolarHBondContact O-CA 3.45Å; A220-H223 VanDerWaalsContact O-CB 3.31Å; A220-H223 WeakPolarHBondContact O-CB 3.42Å; A220-H223 PolarHBondContact O-N 2.98Å; A221-H223 PolarHBondContact O-N 3.33Å; A221-H223 VanDerWaalsContact O-N 3.12Å
224M98.7Very high98.3Very high4 Ų423.8 Ų23.82%0.0211%0.107CC..SBendtrans-114.6149.6176.8-60.9179.7-8900110.2I124 N125 R180 L192 I218 D219 A221 I229 Y269I124-M224 HydrophobicContact CD1-CE 4.33Å; I124-M224 HydrophobicContact CD1-SD 4.23Å; I124-M224 HydrophobicContact CG1-CE 3.86Å; I124-M224 HydrophobicContact CG1-SD 3.86Å; N125-M224 HydrophobicContact CB-CE 4.06Å; N125-M224 HydrophobicContact CB-CG 3.88Å; N125-M224 HydrophobicContact CB-SD 3.89Å; N125-M224 WeakPolarHBondContact OD1-CG 3.35Å; R180-M224 PolarHBondContact NE-O 3.12Å; L192-M224 HydrophobicContact CD1-CB 4.19Å; L192-M224 HydrophobicContact CD1-CG 3.59Å; L192-M224 HydrophobicContact CD1-SD 3.22Å; L192-M224 WeakPolarHBondContact CD1-SD 3.44Å; I218-M224 HydrophobicContact CG2-CE 3.33Å; D219-M224 WeakPolarHBondContact O-CE 3.39Å; A221-M224 HydrophobicContact CB-CE 4.28Å; A221-M224 PolarHBondContact O-N 3.33Å; M224-I229 HydrophobicContact CB-CD1 3.97Å; M224-I229 HydrophobicContact CB-CG1 3.87Å; M224-I229 HydrophobicContact CE-CD1 4.25Å; M224-I229 HydrophobicContact CE-CG1 4.43Å; M224-I229 HydrophobicContact SD-CG1 4.23Å; M224-Y269 PolarHBondContact O-OH 2.96Å
225Y98.4Very high98.3Very high66 Ų6627.1 Ų27.126%0.25912%0.119SC..  trans-65.6132.4167.1-74.5-84.4000109.9R180 N181 E227 D228 I229R180-Y225 HydrophobicContact CB-CD2 4Å; R180-Y225 HydrophobicContact CB-CE1 4.47Å; R180-Y225 HydrophobicContact CB-CE2 3.64Å; N181-Y225 PolarHBondContact ND2-OH 3.37Å; Y225-E227 PolarHBondContact O-N 3.02Å; Y225-E227 VanDerWaalsContact O-N 3.17Å; Y225-D228 PolarHBondContact O-N 3.08Å; Y225-I229 PolarHBondContact O-N 2.95Å
226P98.1Very high98.2Very high13 Ų1327.7 Ų27.78%0.08412%0.122CC..Hα-helixtrans-51.9-36.6174.2-27.734.6000112.7D228 I229 W230 E268 Y269 L272P226-D228 VanDerWaalsContact C-N 3.35Å; P226-D228 PolarHBondContact O-N 2.88Å; P226-I229 PolarHBondContact O-N 2.67Å; P226-W230 WeakPolarHBondContact O-CB 3.44Å; P226-W230 PolarHBondContact O-N 2.83Å; P226-E268 HydrophobicContact CG-CB 4.13Å; P226-Y269 HydrophobicContact CB-CE1 4.44Å; P226-Y269 HydrophobicContact CG-CD1 4.21Å; P226-Y269 HydrophobicContact CG-CE1 3.84Å; P226-Y269 HydrophobicContact CG-CE2 4.2Å; P226-L272 HydrophobicContact CB-CD1 3.75Å; P226-L272 WeakPolarHBondContact O-CD1 3.21Å
227E98.2Very high98.2Very high119 Ų11932 Ų3256%0.55614%0.141SC*.Hα-helixtrans-62.5-40.3177.9-66.873.7-162.300112.3Y225 W230 Q231Y225-E227 PolarHBondContact O-N 3.02Å; Y225-E227 VanDerWaalsContact O-N 3.17Å; E227-W230 WeakPolarHBondContact O-CB 3.22Å; E227-W230 PolarHBondContact O-N 2.68Å; E227-Q231 VanDerWaalsContact O-CG 3.32Å; E227-Q231 WeakPolarHBondContact O-CG 3.48Å; E227-Q231 PolarHBondContact O-N 3.08Å
228D98.5Very high98.1Very high26 Ų2635.3 Ų35.314%0.13916%0.155CC..Hα-helixtrans-71.4-40.6-179.8-70.9-23.2000111.3L192 S193 Y225 P226 W230 Q231 I232L192-D228 HydrophobicContact CB-CB 3.8Å; S193-D228 PolarHBondContact N-OD2 3.3Å; Y225-D228 PolarHBondContact O-N 3.08Å; P226-D228 VanDerWaalsContact C-N 3.35Å; P226-D228 PolarHBondContact O-N 2.88Å; D228-W230 VanDerWaalsContact C-N 3.32Å; D228-W230 PolarHBondContact O-N 3.2Å; D228-Q231 WeakPolarHBondContact O-CB 3.24Å; D228-Q231 PolarHBondContact O-N 2.84Å; D228-I232 PolarHBondContact O-N 3.49Å
229I98.5Very high98.1Very high1 Ų135.4 Ų35.41%0.00516%0.156CC..Hα-helixtrans-57.7-47.8170.1-62177.2000109.6A221 M224 Y225 P226 Q231 I232 L233 Y269 L272A221-I229 HydrophobicContact CB-CD1 4.1Å; M224-I229 HydrophobicContact CB-CD1 3.97Å; M224-I229 HydrophobicContact CB-CG1 3.87Å; M224-I229 HydrophobicContact CE-CD1 4.25Å; M224-I229 HydrophobicContact CE-CG1 4.43Å; M224-I229 HydrophobicContact SD-CG1 4.23Å; Y225-I229 PolarHBondContact O-N 2.95Å; P226-I229 PolarHBondContact O-N 2.67Å; I229-Q231 VanDerWaalsContact C-N 3.29Å; I229-Q231 PolarHBondContact O-N 2.87Å; I229-I232 WeakPolarHBondContact O-CA 3.01Å; I229-I232 WeakPolarHBondContact O-CB 3.23Å; I229-I232 PolarHBondContact O-N 2.84Å; I229-L233 HydrophobicContact CG2-CD1 3.91Å; I229-L233 HydrophobicContact CG2-CG 3.98Å; I229-L233 WeakPolarHBondContact O-CG 3.44Å; I229-L233 PolarHBondContact O-N 3Å; I229-Y269 HydrophobicContact CD1-CD1 3.96Å; I229-Y269 HydrophobicContact CD1-CE1 3.78Å; I229-L272 HydrophobicContact CB-CD1 4.02Å; I229-L272 HydrophobicContact CG2-CD1 4.02Å
230W97.6Very high98.1Very high77 Ų7736.4 Ų36.429%0.29216%0.161SC..Hα-helixtrans-58.1-40.5177.8175.8-114.5000112.7F25 P226 E227 D228 I232 L233 K234 L272F25-W230 AromaticContact CE2-CZ3 3.97Å; F25-W230 HydrophobicContact CE2-CZ3 3.97Å; P226-W230 WeakPolarHBondContact O-CB 3.44Å; P226-W230 PolarHBondContact O-N 2.83Å; E227-W230 WeakPolarHBondContact O-CB 3.22Å; E227-W230 PolarHBondContact O-N 2.68Å; D228-W230 VanDerWaalsContact C-N 3.32Å; D228-W230 PolarHBondContact O-N 3.2Å; W230-I232 PolarHBondContact O-N 3.4Å; W230-L233 PolarHBondContact O-N 3.3Å; W230-K234 HydrophobicContact CZ2-CB 4.48Å; W230-K234 WeakPolarHBondContact O-CG 3.49Å; W230-K234 PolarHBondContact O-N 2.99Å; W230-L272 HydrophobicContact CB-CD2 3.75Å; W230-L272 HydrophobicContact CD2-CD2 4.39Å; W230-L272 HydrophobicContact CE3-CD2 3.84Å; W230-L272 HydrophobicContact CG-CD2 4.4Å
231Q98.2Very high98.1Very high57 Ų5740.8 Ų40.827%0.26619%0.188SC..Hα-helixtrans-60.1-36175.8-67.9-51.3-54.300111.8Q198 E227 D228 I229 K234 R235Q198-Q231 VanDerWaalsContact CD-CB 3.43Å; Q198-Q231 HydrophobicContact CG-CB 4.33Å; Q198-Q231 VanDerWaalsContact OE1-CB 3.27Å; E227-Q231 VanDerWaalsContact O-CG 3.32Å; E227-Q231 WeakPolarHBondContact O-CG 3.48Å; E227-Q231 PolarHBondContact O-N 3.08Å; D228-Q231 WeakPolarHBondContact O-CB 3.24Å; D228-Q231 PolarHBondContact O-N 2.84Å; I229-Q231 VanDerWaalsContact C-N 3.29Å; I229-Q231 PolarHBondContact O-N 2.87Å; Q231-K234 WeakPolarHBondContact O-CG 3.38Å; Q231-R235 WeakPolarHBondContact O-CG 3.38Å; Q231-R235 PolarHBondContact O-NH1 2.97Å
232I98.5Very high98.1Very high1 Ų147.2 Ų47.21%0.00522%0.222CC..Hα-helixtrans-71.8-50.4174.9-65160.8000110.2I124 L192 Q198 V201 A202 L205 D228 I229 W230 K234 R235I124-I232 HydrophobicContact CD1-CD1 4.23Å; L192-I232 HydrophobicContact CD1-CD1 4.46Å; L192-I232 HydrophobicContact CD2-CD1 4.28Å; Q198-I232 HydrophobicContact CB-CG1 3.97Å; Q198-I232 HydrophobicContact CG-CG1 4.09Å; V201-I232 HydrophobicContact CB-CD1 4.28Å; V201-I232 HydrophobicContact CG1-CD1 3.99Å; V201-I232 HydrophobicContact CG1-CG1 4.43Å; V201-I232 HydrophobicContact CG1-CG2 3.85Å; A202-I232 HydrophobicContact CB-CG2 4.38Å; L205-I232 HydrophobicContact CD1-CG2 3.88Å; D228-I232 PolarHBondContact O-N 3.49Å; I229-I232 WeakPolarHBondContact O-CA 3.01Å; I229-I232 WeakPolarHBondContact O-CB 3.23Å; I229-I232 PolarHBondContact O-N 2.84Å; W230-I232 PolarHBondContact O-N 3.4Å; I232-K234 VanDerWaalsContact C-N 3.32Å; I232-K234 PolarHBondContact O-N 2.8Å; I232-R235 WeakPolarHBondContact O-CB 3.32Å; I232-R235 PolarHBondContact O-N 3.07Å
233L97.9Very high98.1Very high1 Ų149.9 Ų49.91%0.00523%0.234CC..Hα-helixtrans-57.9-40.4-175.6-67.5-174.7000112.9F25 I229 W230 R235 L236 I252 L272F25-L233 HydrophobicContact CD2-CD1 4.48Å; F25-L233 HydrophobicContact CE1-CB 4.42Å; F25-L233 HydrophobicContact CE2-CB 4.13Å; F25-L233 HydrophobicContact CE2-CD1 4.42Å; F25-L233 HydrophobicContact CZ-CB 3.82Å; I229-L233 HydrophobicContact CG2-CD1 3.91Å; I229-L233 HydrophobicContact CG2-CG 3.98Å; I229-L233 WeakPolarHBondContact O-CG 3.44Å; I229-L233 PolarHBondContact O-N 3Å; W230-L233 PolarHBondContact O-N 3.3Å; L233-R235 PolarHBondContact O-N 2.85Å; L233-R235 VanDerWaalsContact O-N 3.16Å; L233-L236 HydrophobicContact CD2-CD1 3.69Å; L233-L236 VanDerWaalsContact O-CB 3.32Å; L233-L236 WeakPolarHBondContact O-CB 3.16Å; L233-L236 WeakPolarHBondContact O-CG 3.24Å; L233-L236 PolarHBondContact O-N 3.16Å; L233-I252 HydrophobicContact CD1-CG1 4.49Å; L233-I252 HydrophobicContact CD1-CG2 4.5Å; L233-I252 HydrophobicContact CD2-CD1 3.73Å; L233-I252 HydrophobicContact CD2-CG1 3.94Å; L233-L272 HydrophobicContact CD1-CB 4.03Å; L233-L272 HydrophobicContact CD1-CD2 4.48Å
234K96.3Very high98.1Very high100 Ų10049.9 Ų49.944%0.43523%0.234SC..THydrogen-bonded Turntrans-68.2-11.7178.172.8174.8-171.5175.20114.6W230 Q231 I232W230-K234 HydrophobicContact CZ2-CB 4.48Å; W230-K234 WeakPolarHBondContact O-CG 3.49Å; W230-K234 PolarHBondContact O-N 2.99Å; Q231-K234 WeakPolarHBondContact O-CG 3.38Å; I232-K234 VanDerWaalsContact C-N 3.32Å; I232-K234 PolarHBondContact O-N 2.8Å
235R97.8Very high98Very high70 Ų7053.4 Ų53.426%0.26426%0.257SS..THydrogen-bonded Turntrans-95.1-3.2175.6-67.3173.8168.294.4-14.3111.9A202 N206 Q231 I232 L233A202-R235 HydrophobicContact CB-CB 3.7Å; N206-R235 PolarHBondContact ND2-O 3.33Å; Q231-R235 WeakPolarHBondContact O-CG 3.38Å; Q231-R235 PolarHBondContact O-NH1 2.97Å; I232-R235 WeakPolarHBondContact O-CB 3.32Å; I232-R235 PolarHBondContact O-N 3.07Å; L233-R235 PolarHBondContact O-N 2.85Å; L233-R235 VanDerWaalsContact O-N 3.16Å
236L98.3Very high97.9Very high12 Ų1254.5 Ų54.56%0.06327%0.272CS..PPolyproline II helixtrans-72.9142.4178.1-59.9-176.4000110.8L205 N206 I209 L233 P250L205-L236 HydrophobicContact CB-CD2 3.55Å; L205-L236 HydrophobicContact CD1-CD2 4.02Å; L205-L236 HydrophobicContact CG-CD2 4.44Å; N206-L236 VanDerWaalsContact OD1-CA 3.27Å; N206-L236 WeakPolarHBondContact OD1-CA 3.46Å; I209-L236 HydrophobicContact CD1-CB 4.14Å; I209-L236 HydrophobicContact CD1-CD2 4.4Å; L233-L236 HydrophobicContact CD2-CD1 3.69Å; L233-L236 VanDerWaalsContact O-CB 3.32Å; L233-L236 WeakPolarHBondContact O-CB 3.16Å; L233-L236 WeakPolarHBondContact O-CG 3.24Å; L233-L236 PolarHBondContact O-N 3.16Å; L236-P250 HydrophobicContact CD1-CG 3.89Å
237K97.8Very high97.8Very high91 Ų9159.9 Ų59.940%0.39630%0.301SS..PPolyproline II helixtrans-66.1160.3169.3-68.3171.8177.3-179.20109.6N206 I209 D210N206-K237 HydrophobicContact CB-CD 4.06Å; N206-K237 HydrophobicContact CB-CG 4.35Å; N206-K237 WeakPolarHBondContact OD1-CG 3.4Å; N206-K237 PolarHBondContact OD1-N 3.2Å; I209-K237 HydrophobicContact CG2-CB 4.25Å; D210-K237 WeakPolarHBondContact OD1-CD 3.2Å; D210-K237 IonicContact OD1-NZ 3.46Å; D210-K237 PolarHBondContact OD1-NZ 3.09Å; D210-K237 IonicContact OD2-NZ 3.45Å; D210-K237 PolarHBondContact OD2-NZ 2.87Å
238K97.8Very high97.7Very high70 Ų7056.8 Ų56.830%0.30429%0.285SS..PPolyproline II helixtrans-64.1155.3156.7-62.8-59.2-169.3159.80109.2I209 D247 K248 C249I209-K238 WeakPolarHBondContact CG2-O 3.42Å; K238-D247 PolarHBondContact NZ-O 2.83Å; K238-K248 WeakPolarHBondContact CA-O 3.4Å; K238-K248 WeakPolarHBondContact CB-O 3.44Å; K238-K248 WeakPolarHBondContact CD-O 3.26Å; K238-C249 PolarHBondContact NZ-SG 2.85Å
239L98.6Very high97.6Very high3 Ų355.7 Ų55.72%0.01628%0.279CS..PPolyproline II helixtrans-58.7146.6179.1-69.3-179.1000111.6Q29 I209 V213 T241 F244 K248 C249 P250Q29-L239 HydrophobicContact CG-CD1 3.68Å; I209-L239 HydrophobicContact CG1-CD2 4.37Å; I209-L239 HydrophobicContact CG2-CD2 4.23Å; V213-L239 WeakPolarHBondContact O-CD2 3.32Å; L239-T241 PolarHBondContact O-N 2.94Å; L239-F244 HydrophobicContact CB-CB 3.93Å; L239-F244 HydrophobicContact CB-CD2 3.66Å; L239-F244 HydrophobicContact CB-CE2 4.31Å; L239-F244 HydrophobicContact CB-CG 3.81Å; L239-F244 HydrophobicContact CD1-CB 4.42Å; L239-F244 HydrophobicContact CD1-CD1 3.72Å; L239-F244 HydrophobicContact CD1-CD2 4.09Å; L239-F244 HydrophobicContact CD1-CE1 3.89Å; L239-F244 HydrophobicContact CD1-CE2 4.27Å; L239-F244 HydrophobicContact CD1-CG 3.82Å; L239-F244 HydrophobicContact CD1-CZ 4.18Å; L239-F244 HydrophobicContact CD2-CE2 4.49Å; L239-F244 HydrophobicContact CG-CD2 4.35Å; L239-F244 HydrophobicContact CG-CG 4.43Å; L239-K248 HydrophobicContact CB-CB 4.29Å; L239-K248 HydrophobicContact CD1-CB 4.04Å; L239-K248 HydrophobicContact CG-CB 4.43Å; L239-K248 PolarHBondContact N-O 3.2Å; L239-C249 VanDerWaalsContact CD1-O 3.28Å; L239-C249 WeakPolarHBondContact CD1-O 3.48Å; L239-P250 HydrophobicContact CD2-CB 3.94Å
240N98.5Very high97.6Very high33 Ų3355.6 Ų55.618%0.17628%0.279CS..PPolyproline II helixtrans-59.7121.4-179.1-179.9-8.8000110.7I209 D210 D242 F243 F244I209-N240 WeakPolarHBondContact O-CB 3.45Å; D210-N240 PolarHBondContact O-ND2 3.03Å; N240-D242 PolarHBondContact O-N 3.2Å; N240-D242 WeakPolarHBondContact OD1-CB 3.33Å; N240-D242 PolarHBondContact OD1-N 3.16Å; N240-F243 HydrophobicContact CB-CD2 4.17Å; N240-F243 PolarHBondContact O-N 3.16Å; N240-F244 WeakPolarHBondContact O-CD2 3.21Å; N240-F244 PolarHBondContact O-N 3.35Å
241T98.4Very high97.7Very high94 Ų9452 Ų5258%0.57727%0.265SS*.THydrogen-bonded Turntrans-69.7-9.6-176.252.20000114.7L239 F243 F244 P246L239-T241 PolarHBondContact O-N 2.94Å; T241-F243 PolarHBondContact O-N 3.05Å; T241-F244 WeakPolarHBondContact CA-O 3.43Å; T241-P246 HydrophobicContact CG2-CB 4.44Å
242D98.2Very high97.7Very high136 Ų13649.2 Ų49.273%0.72725%0.252SS*.THydrogen-bonded Turntrans-69-24.8170.1-66-18.6000111.6N240N240-D242 PolarHBondContact O-N 3.2Å; N240-D242 WeakPolarHBondContact OD1-CB 3.33Å; N240-D242 PolarHBondContact OD1-N 3.16Å
243F98.3Very high97.7Very high63 Ų6349.2 Ų49.228%0.27625%0.252SS..THydrogen-bonded Turntrans-118-25.6-175.6-59.4-75.1000113.8H112 G212 N240 T241H112-F243 HydrophobicContact CB-CD1 3.88Å; H112-F243 HydrophobicContact CB-CE1 4.36Å; H112-F243 AromaticContact CD2-CD1 3.32Å; H112-F243 WeakPolarHBondContact CD2-CD1 3.25Å; H112-F243 AromaticContact CD2-CE1 3.91Å; H112-F243 AromaticContact CD2-CG 3.76Å; H112-F243 AromaticContact CG-CD1 3.59Å; H112-F243 AromaticContact NE2-CD1 3.86Å; H112-F243 AromaticContact NE2-CG 3.8Å; G212-F243 VanDerWaalsContact CA-CD2 3.49Å; N240-F243 HydrophobicContact CB-CD2 4.17Å; N240-F243 PolarHBondContact O-N 3.16Å; T241-F243 PolarHBondContact O-N 3.05Å
244F98.2Very high97.8Very high10 Ų1049.1 Ų49.14%0.04425%0.252CS..SBendtrans-126.2154.7-174.6-59.3-89.9000111.8Q29 H112 K117 G212 A214 L239 N240 T241Q29-F244 HydrophobicContact CB-CD1 4.13Å; Q29-F244 HydrophobicContact CB-CE1 3.84Å; Q29-F244 HydrophobicContact CG-CD1 4.47Å; Q29-F244 HydrophobicContact CG-CE1 4.32Å; H112-F244 AromaticContact CE1-CE1 3.96Å; H112-F244 AromaticContact CE1-CE2 3.69Å; H112-F244 AromaticContact CE1-CZ 3.37Å; H112-F244 WeakPolarHBondContact CE1-CZ 3.27Å; H112-F244 AromaticContact NE2-CE2 3.82Å; H112-F244 AromaticContact NE2-CZ 3.77Å; K117-F244 HydrophobicContact CD-CE1 3.72Å; K117-F244 HydrophobicContact CD-CZ 4.08Å; G212-F244 WeakPolarHBondContact O-CE2 3.4Å; A214-F244 VanDerWaalsContact CA-CZ 3.5Å; A214-F244 HydrophobicContact CB-CE1 3.79Å; A214-F244 HydrophobicContact CB-CZ 3.5Å; A214-F244 VanDerWaalsContact CB-CZ 3.5Å; L239-F244 HydrophobicContact CB-CB 3.93Å; L239-F244 HydrophobicContact CB-CD2 3.66Å; L239-F244 HydrophobicContact CB-CE2 4.31Å; L239-F244 HydrophobicContact CB-CG 3.81Å; L239-F244 HydrophobicContact CD1-CB 4.42Å; L239-F244 HydrophobicContact CD1-CD1 3.72Å; L239-F244 HydrophobicContact CD1-CD2 4.09Å; L239-F244 HydrophobicContact CD1-CE1 3.89Å; L239-F244 HydrophobicContact CD1-CE2 4.27Å; L239-F244 HydrophobicContact CD1-CG 3.82Å; L239-F244 HydrophobicContact CD1-CZ 4.18Å; L239-F244 HydrophobicContact CD2-CE2 4.49Å; L239-F244 HydrophobicContact CG-CD2 4.35Å; L239-F244 HydrophobicContact CG-CG 4.43Å; N240-F244 WeakPolarHBondContact O-CD2 3.21Å; N240-F244 PolarHBondContact O-N 3.35Å; T241-F244 WeakPolarHBondContact CA-O 3.43Å
245P96.5Very high97.9Very high78 Ų7845 Ų4551%0.50623%0.234SC..  trans-54.7153.9166.1-23.634.3000112K248P245-K248 HydrophobicContact CB-CG 4.2Å; P245-K248 WeakPolarHBondContact O-CG 3.4Å
246P96.2Very high97.8Very high90 Ų9041.7 Ų41.758%0.58422%0.222SC*.THydrogen-bonded Turntrans-58.9156.5176.525.6-34.6000112.5T241 K248T241-P246 HydrophobicContact CG2-CB 4.44Å; P246-K248 PolarHBondContact O-N 2.84Å; P246-K248 VanDerWaalsContact O-N 3.13Å
247D94.8Very high97.7Very high126 Ų12642.2 Ų42.267%0.67422%0.224SC*.THydrogen-bonded Turntrans65.84.1175.4-58.6-53.3000117.2K238K238-D247 PolarHBondContact NZ-O 2.83Å
248K97.1Very high97.5Very high54 Ų5438.2 Ų38.224%0.23521%0.207CC..PPolyproline II helixtrans-69.7143.8175.4-66.3-58.1-161.3171.70113.2E27 K238 L239 P245 P246E27-K248 IonicContact OE1-NZ 2.71Å; E27-K248 PolarHBondContact OE1-NZ 3.38Å; E27-K248 IonicContact OE2-NZ 2.61Å; E27-K248 PolarHBondContact OE2-NZ 3.42Å; K238-K248 WeakPolarHBondContact CA-O 3.4Å; K238-K248 WeakPolarHBondContact CB-O 3.44Å; K238-K248 WeakPolarHBondContact CD-O 3.26Å; L239-K248 HydrophobicContact CB-CB 4.29Å; L239-K248 HydrophobicContact CD1-CB 4.04Å; L239-K248 HydrophobicContact CG-CB 4.43Å; L239-K248 PolarHBondContact N-O 3.2Å; P245-K248 HydrophobicContact CB-CG 4.2Å; P245-K248 WeakPolarHBondContact O-CG 3.4Å; P246-K248 PolarHBondContact O-N 2.84Å; P246-K248 VanDerWaalsContact O-N 3.13Å
249C97.3Very high97.2Very high2 Ų237.7 Ų37.71%0.01421%0.206CC..PPolyproline II helixtrans-100.8153.3176.6-63.10000110.6Q20 C24 F25 Q29 K238 L239Q20-C249 PolarHBondContact NE2-SG 3.08Å; C24-C249 HydrophobicContact CB-CB 3.78Å; C24-C249 WeakPolarHBondContact CB-SG 2.89Å; C24-C249 WeakPolarHBondContact O-CB 3.42Å; C24-C249 WeakPolarHBondContact SG-CB 3.4Å; C24-C249 CovalentContact SG-SG 2.04Å; C24-C249 PolarHBondContact SG-SG 3.11Å; F25-C249 HydrophobicContact CD1-CB 4.24Å; F25-C249 HydrophobicContact CE1-CB 4.46Å; Q29-C249 PolarHBondContact NE2-O 3.24Å; K238-C249 PolarHBondContact NZ-SG 2.85Å; L239-C249 VanDerWaalsContact CD1-O 3.28Å; L239-C249 WeakPolarHBondContact CD1-O 3.48Å
250P98.4Very high96.7Very high0 Ų039.1 Ų39.10%022%0.221CC..PPolyproline II helixtrans-62139.4169.926.6-33.5000110.7F25 I209 A214 F216 L236 L239 I252F25-P250 HydrophobicContact CD1-CG 4.25Å; F25-P250 WeakPolarHBondContact CD1-O 3.43Å; F25-P250 HydrophobicContact CE1-CG 4.08Å; I209-P250 HydrophobicContact CD1-CB 4.45Å; I209-P250 HydrophobicContact CD1-CG 4.12Å; A214-P250 CarbonylContact O-C 3.27Å; A214-P250 VanDerWaalsContact O-CA 3.31Å; A214-P250 WeakPolarHBondContact O-CA 3.41Å; F216-P250 HydrophobicContact CD2-CB 4.14Å; F216-P250 HydrophobicContact CE2-CB 3.94Å; F216-P250 HydrophobicContact CE2-CG 4.42Å; L236-P250 HydrophobicContact CD1-CG 3.89Å; L239-P250 HydrophobicContact CD2-CB 3.94Å; P250-I252 HydrophobicContact CB-CD1 4.49Å; P250-I252 HydrophobicContact CG-CD1 4.47Å
251F98.5Very high96.3Very high0 Ų042.5 Ų42.50%025%0.245CC..EExtended strand (participates in β ladder)trans-64.4132168.5174.6-112.4000109.8F25 E27 L28 I119 A214 G215 F216 V253 R274 L313 I354F25-F251 CarbonylContact O-C 3.57Å; F25-F251 WeakPolarHBondContact O-CA 3.17Å; E27-F251 WeakPolarHBondContact O-CB 3.49Å; L28-F251 HydrophobicContact CB-CD2 4.37Å; L28-F251 HydrophobicContact CD1-CD1 3.74Å; L28-F251 HydrophobicContact CD1-CD2 4.31Å; L28-F251 HydrophobicContact CD1-CE1 3.77Å; L28-F251 HydrophobicContact CD1-CE2 4.33Å; L28-F251 HydrophobicContact CD1-CG 4.01Å; L28-F251 HydrophobicContact CD1-CZ 4.07Å; I119-F251 HydrophobicContact CD1-CD1 3.87Å; I119-F251 HydrophobicContact CD1-CE1 4.16Å; I119-F251 HydrophobicContact CG1-CD1 4.37Å; A214-F251 PolarHBondContact O-N 3.5Å; G215-F251 CarbonylContact C-O 3.51Å; G215-F251 WeakPolarHBondContact CA-O 3.5Å; F216-F251 PolarHBondContact N-O 3.04Å; F251-V253 HydrophobicContact CE1-CB 3.96Å; F251-V253 HydrophobicContact CE1-CG1 3.85Å; F251-V253 HydrophobicContact CZ-CB 4.04Å; F251-V253 HydrophobicContact CZ-CG1 4.41Å; F251-R274 HydrophobicContact CE2-CG 4.05Å; F251-R274 HydrophobicContact CZ-CG 4.46Å; F251-L313 HydrophobicContact CE1-CD1 4.48Å; F251-I354 HydrophobicContact CE2-CD1 3.7Å; F251-I354 HydrophobicContact CZ-CD1 3.76Å
252I98.7Very high96Very high0 Ų040 Ų400%023%0.227CC..EExtended strand (participates in β ladder)trans-120.6131.9175.9-53.8-64.9000109.5F25 F216 I218 L233 P250 L272 R274F25-I252 HydrophobicContact CB-CB 4.07Å; F25-I252 HydrophobicContact CB-CG1 3.82Å; F25-I252 HydrophobicContact CD1-CD1 4.43Å; F25-I252 HydrophobicContact CD1-CG1 3.54Å; F25-I252 HydrophobicContact CE1-CG1 4.34Å; F25-I252 HydrophobicContact CG-CG1 3.91Å; F25-I252 PolarHBondContact O-N 3.36Å; F216-I252 HydrophobicContact CB-CD1 4.1Å; F216-I252 HydrophobicContact CD2-CD1 3.77Å; F216-I252 HydrophobicContact CG-CD1 4.44Å; F216-I252 WeakPolarHBondContact O-CA 3.26Å; I218-I252 HydrophobicContact CG1-CG2 3.94Å; L233-I252 HydrophobicContact CD1-CG1 4.49Å; L233-I252 HydrophobicContact CD1-CG2 4.5Å; L233-I252 HydrophobicContact CD2-CD1 3.73Å; L233-I252 HydrophobicContact CD2-CG1 3.94Å; P250-I252 HydrophobicContact CB-CD1 4.49Å; P250-I252 HydrophobicContact CG-CD1 4.47Å; I252-L272 WeakPolarHBondContact CG2-O 3.19Å; I252-R274 PolarHBondContact O-N 2.83Å
253V98.7Very high95.8Very high0 Ų035.3 Ų35.30%021%0.206CC..EExtended strand (participates in β ladder)trans-129.9120.4166.159.80000109.9F216 R217 I218 F251 R274 T276 L313F216-V253 PolarHBondContact O-N 3.45Å; R217-V253 CarbonylContact C-O 3.59Å; R217-V253 VanDerWaalsContact CA-O 3.25Å; R217-V253 WeakPolarHBondContact CA-O 3.49Å; R217-V253 HydrophobicContact CB-CG1 3.65Å; R217-V253 HydrophobicContact CG-CG1 3.89Å; I218-V253 PolarHBondContact N-O 3.2Å; F251-V253 HydrophobicContact CE1-CB 3.96Å; F251-V253 HydrophobicContact CE1-CG1 3.85Å; F251-V253 HydrophobicContact CZ-CB 4.04Å; F251-V253 HydrophobicContact CZ-CG1 4.41Å; V253-R274 CarbonylContact C-O 3.56Å; V253-R274 WeakPolarHBondContact CA-O 3.24Å; V253-R274 HydrophobicContact CB-CB 4.34Å; V253-R274 HydrophobicContact CG2-CB 4.25Å; V253-T276 HydrophobicContact CG2-CG2 3.98Å; V253-L313 HydrophobicContact CB-CD1 4.43Å; V253-L313 HydrophobicContact CG1-CD1 4.13Å; V253-L313 HydrophobicContact CG2-CB 3.76Å; V253-L313 HydrophobicContact CG2-CD1 4.17Å
254N98.7Very high95.8Very high0 Ų032.3 Ų32.30%019%0.194CC..EExtended strand (participates in β ladder)trans-88.9125.7-178-62.7-78.7000109.8A221 V256 L272 R274 I275 T276A221-N254 HydrophobicContact CB-CB 3.66Å; N254-V256 HydrophobicContact CB-CG2 4.17Å; N254-V256 PolarHBondContact O-N 2.89Å; N254-V256 VanDerWaalsContact O-N 3.1Å; N254-L272 PolarHBondContact ND2-O 3.46Å; N254-R274 PolarHBondContact N-O 2.91Å; N254-R274 PolarHBondContact ND2-O 2.93Å; N254-R274 VanDerWaalsContact ND2-O 3.13Å; N254-I275 HydrophobicContact CB-CG2 4.33Å; N254-I275 WeakPolarHBondContact O-CA 3.19Å; N254-T276 PolarHBondContact O-N 3.11Å; N254-T276 PolarHBondContact O-OG1 3.07Å
255E98.3Very high95.7Very high12 Ų1235.3 Ų35.36%0.05621%0.206CC..  trans-74.9101.5170.7-168.9-136.9-141.100110.8R217 I218 A220 A221 K222 T276 F278R217-E255 IonicContact NH2-OE1 2.73Å; R217-E255 PolarHBondContact NH2-OE1 3.3Å; R217-E255 IonicContact NH2-OE2 3.34Å; I218-E255 VanDerWaalsContact O-CB 3.27Å; I218-E255 WeakPolarHBondContact O-CB 3.44Å; I218-E255 PolarHBondContact O-N 3.44Å; A220-E255 VanDerWaalsContact CA-OE2 3.3Å; A220-E255 WeakPolarHBondContact CA-OE2 3.42Å; A220-E255 PolarHBondContact N-OE2 3.37Å; A220-E255 VanDerWaalsContact N-OE2 3.08Å; A221-E255 WeakPolarHBondContact CA-O 3.28Å; A221-E255 WeakPolarHBondContact CB-O 3.38Å; A221-E255 PolarHBondContact N-O 2.68Å; K222-E255 PolarHBondContact N-O 3.39Å; E255-T276 WeakPolarHBondContact CA-OG1 3.04Å; E255-F278 HydrophobicContact CG-CE2 3.96Å; E255-F278 HydrophobicContact CG-CZ 4.13Å
256V97.5Very high95.7Very high1 Ų131.6 Ų31.61%0.00618%0.182CC..  trans-121104.1174.7-171.10000108.8A221 K222 N254 D258 Y269 I275 T276A221-V256 HydrophobicContact CB-CG2 4.33Å; K222-V256 HydrophobicContact CB-CG1 4.26Å; K222-V256 HydrophobicContact CG-CG1 4.46Å; N254-V256 HydrophobicContact CB-CG2 4.17Å; N254-V256 PolarHBondContact O-N 2.89Å; N254-V256 VanDerWaalsContact O-N 3.1Å; V256-D258 VanDerWaalsContact C-N 3.3Å; V256-D258 HydrophobicContact CG1-CB 4.41Å; V256-D258 PolarHBondContact O-N 3.06Å; V256-Y269 HydrophobicContact CG1-CD2 4.23Å; V256-Y269 HydrophobicContact CG1-CE2 4.28Å; V256-Y269 HydrophobicContact CG2-CD1 4.17Å; V256-Y269 HydrophobicContact CG2-CD2 3.6Å; V256-Y269 HydrophobicContact CG2-CE2 4.05Å; V256-Y269 HydrophobicContact CG2-CG 3.67Å; V256-I275 HydrophobicContact CG2-CG2 4.28Å; V256-T276 PolarHBondContact N-OG1 2.95Å
257I94.4Very high95.8Very high23 Ų2330.6 Ų30.612%0.11818%0.178CC..  trans-7290172.6-58.8164.9000108.1K222 E262 F278K222-I257 HydrophobicContact CD-CB 4.26Å; K222-I257 WeakPolarHBondContact CD-O 3.34Å; K222-I257 WeakPolarHBondContact CE-O 3.5Å; K222-I257 PolarHBondContact NZ-O 2.99Å; I257-E262 WeakPolarHBondContact O-CG 3.42Å; I257-F278 HydrophobicContact CB-CD2 4.39Å; I257-F278 HydrophobicContact CB-CE2 4.34Å; I257-F278 HydrophobicContact CD1-CZ 4.43Å; I257-F278 HydrophobicContact CG1-CD2 4.1Å; I257-F278 HydrophobicContact CG1-CE1 4.07Å; I257-F278 HydrophobicContact CG1-CE2 3.59Å; I257-F278 HydrophobicContact CG1-CZ 3.58Å
258D94.2Very high95.9Very high8 Ų827.9 Ų27.94%0.04316%0.161CC..  trans-120106.4171.5-176-1.6000110.4V256 G260 K265 G266 W307V256-D258 VanDerWaalsContact C-N 3.3Å; V256-D258 HydrophobicContact CG1-CB 4.41Å; V256-D258 PolarHBondContact O-N 3.06Å; D258-G260 PolarHBondContact OD1-N 2.83Å; D258-K265 WeakPolarHBondContact OD2-CA 3.32Å; D258-G266 PolarHBondContact OD2-N 2.97Å; D258-W307 HydrophobicContact CB-CH2 3.95Å; D258-W307 HydrophobicContact CB-CZ2 4.31Å; D258-W307 VanDerWaalsContact OD2-CZ2 3.32Å; D258-W307 WeakPolarHBondContact OD2-CZ2 3.32Å
259Q91.2Very high95.9Very high59 Ų5925.3 Ų25.328%0.27615%0.15SC..  trans-100.88178-62.1-172.1-2.900113.3P261 F278 L282 G327Q259-P261 WeakPolarHBondContact O-CD 3.41Å; Q259-F278 HydrophobicContact CG-CB 4.27Å; Q259-L282 HydrophobicContact CG-CD1 4.03Å; Q259-G327 PolarHBondContact NE2-O 3.42Å
260G88.9Confident95.9Very high32 Ų3226.6 Ų26.633%0.3316%0.158SC..SBendtrans116.9-61-177.200000113.7D258 E262 K265D258-G260 PolarHBondContact OD1-N 2.83Å; G260-E262 VanDerWaalsContact C-N 3.31Å; G260-E262 PolarHBondContact O-N 3.38Å; G260-K265 PolarHBondContact O-NZ 2.97Å
261P89.7Confident95.7Very high104 Ų10430 Ų3068%0.67518%0.181SC*.SBendtrans-84.31.4-174.833.4-34.6000114.5Q259Q259-P261 WeakPolarHBondContact O-CD 3.41Å
262E92Very high95.6Very high43 Ų4330.1 Ų30.120%0.20118%0.182CC..  trans-65.6143.6-174-62.1-6314700112.7K222 I257 G260 I264 K265K222-E262 IonicContact NZ-OE2 3.13Å; K222-E262 PolarHBondContact NZ-OE2 2.93Å; I257-E262 WeakPolarHBondContact O-CG 3.42Å; G260-E262 VanDerWaalsContact C-N 3.31Å; G260-E262 PolarHBondContact O-N 3.38Å; E262-I264 VanDerWaalsContact C-N 3.3Å; E262-I264 WeakPolarHBondContact CB-O 3.48Å; E262-I264 PolarHBondContact O-N 2.93Å; E262-K265 WeakPolarHBondContact O-CD 3.45Å; E262-K265 WeakPolarHBondContact O-CE 3.45Å; E262-K265 PolarHBondContact O-NZ 2.61Å
263A94.9Very high95.6Very high36 Ų3630.1 Ų30.130%0.29818%0.182SC..SBendtrans-67.9-31.5179.700000113.2N174 P176N174-A263 WeakPolarHBondContact O-CB 3.38Å; P176-A263 HydrophobicContact CG-CB 4.06Å
264I97.4Very high95.5Very high1 Ų131.6 Ų31.61%0.00519%0.187CC..SBendtrans-98131.2173.1-64.2179.2000108.6P176 V179 R180 K222 E262 Y269P176-I264 HydrophobicContact CB-CD1 4.44Å; P176-I264 HydrophobicContact CB-CG1 4.07Å; P176-I264 HydrophobicContact CG-CG1 4.43Å; V179-I264 HydrophobicContact CB-CD1 3.8Å; V179-I264 HydrophobicContact CG1-CD1 3.42Å; V179-I264 VanDerWaalsContact CG1-CD1 3.42Å; R180-I264 HydrophobicContact CG-CD1 3.91Å; K222-I264 HydrophobicContact CG-CB 4.18Å; K222-I264 HydrophobicContact CG-CD1 4.2Å; K222-I264 HydrophobicContact CG-CG2 4.09Å; K222-I264 WeakPolarHBondContact O-CD1 3.48Å; E262-I264 VanDerWaalsContact C-N 3.3Å; E262-I264 WeakPolarHBondContact CB-O 3.48Å; E262-I264 PolarHBondContact O-N 2.93Å; I264-Y269 HydrophobicContact CG2-CE2 3.69Å
265K97Very high95.5Very high72 Ų7231.6 Ų31.631%0.31319%0.188SC..  trans-103145.1-175.8-57.6-54.1-173.2-172.50111.9D258 G260 E262 S267 E268D258-K265 WeakPolarHBondContact OD2-CA 3.32Å; G260-K265 PolarHBondContact O-NZ 2.97Å; E262-K265 WeakPolarHBondContact O-CD 3.45Å; E262-K265 WeakPolarHBondContact O-CE 3.45Å; E262-K265 PolarHBondContact O-NZ 2.61Å; K265-S267 PolarHBondContact O-N 2.97Å; K265-E268 PolarHBondContact N-OE1 3.06Å; K265-E268 WeakPolarHBondContact O-CB 3.25Å; K265-E268 PolarHBondContact O-N 2.99Å; K265-E268 VanDerWaalsContact O-N 3.11Å
266G96.8Very high95.5Very high0 Ų031.2 Ų31.20%019%0.186CC..G310 helixtrans-57-31.2172.600000113.3D258 E268 Y269D258-G266 PolarHBondContact OD2-N 2.97Å; G266-E268 PolarHBondContact O-N 3.08Å; G266-E268 VanDerWaalsContact O-N 3.13Å; G266-Y269 PolarHBondContact O-N 3.4Å
267S96.6Very high95.5Very high70 Ų7031.1 Ų31.149%0.4919%0.186SC..G310 helixtrans-64.4-16.1179.254.40000114.3K265 Y269 W307K265-S267 PolarHBondContact O-N 2.97Å; S267-Y269 PolarHBondContact O-N 2.93Å; S267-W307 VanDerWaalsContact N-NE1 3.1Å
268E97.7Very high95.5Very high68 Ų6830.3 Ų30.332%0.31818%0.181SC..G310 helixtrans-72.7-14.3174.2-64.1174.7-117.400112.3R180 P226 K265 G266R180-E268 IonicContact CZ-OE2 3.79Å; R180-E268 IonicContact NH1-OE2 3.67Å; R180-E268 PolarHBondContact NH1-OE2 3.03Å; R180-E268 IonicContact NH2-OE2 3.76Å; R180-E268 PolarHBondContact NH2-OE2 3.03Å; P226-E268 HydrophobicContact CG-CB 4.13Å; K265-E268 PolarHBondContact N-OE1 3.06Å; K265-E268 WeakPolarHBondContact O-CB 3.25Å; K265-E268 PolarHBondContact O-N 2.99Å; K265-E268 VanDerWaalsContact O-N 3.11Å; G266-E268 PolarHBondContact O-N 3.08Å; G266-E268 VanDerWaalsContact O-N 3.13Å
269Y97.8Very high95.6Very high0 Ų032.6 Ų32.60%019%0.189CC..THydrogen-bonded Turntrans-118-6.3-171.6-61.9-98.3000114R180 A221 K222 M224 P226 I229 V256 I264 G266 S267 S271 L272R180-Y269 PolarHBondContact NE-OH 3.45Å; R180-Y269 PolarHBondContact NH2-OH 3.49Å; A221-Y269 WeakPolarHBondContact O-CE1 3.16Å; A221-Y269 PolarHBondContact O-OH 3.32Å; K222-Y269 PolarHBondContact O-OH 3.03Å; M224-Y269 PolarHBondContact O-OH 2.96Å; P226-Y269 HydrophobicContact CB-CE1 4.44Å; P226-Y269 HydrophobicContact CG-CD1 4.21Å; P226-Y269 HydrophobicContact CG-CE1 3.84Å; P226-Y269 HydrophobicContact CG-CE2 4.2Å; I229-Y269 HydrophobicContact CD1-CD1 3.96Å; I229-Y269 HydrophobicContact CD1-CE1 3.78Å; V256-Y269 HydrophobicContact CG1-CD2 4.23Å; V256-Y269 HydrophobicContact CG1-CE2 4.28Å; V256-Y269 HydrophobicContact CG2-CD1 4.17Å; V256-Y269 HydrophobicContact CG2-CD2 3.6Å; V256-Y269 HydrophobicContact CG2-CE2 4.05Å; V256-Y269 HydrophobicContact CG2-CG 3.67Å; I264-Y269 HydrophobicContact CG2-CE2 3.69Å; G266-Y269 PolarHBondContact O-N 3.4Å; S267-Y269 PolarHBondContact O-N 2.93Å; Y269-S271 PolarHBondContact O-N 2.87Å; Y269-L272 HydrophobicContact CD1-CD1 4.17Å; Y269-L272 WeakPolarHBondContact O-CB 3.43Å; Y269-L272 PolarHBondContact O-N 2.81Å
270T95.9Very high95.8Very high30 Ų3029.8 Ų29.818%0.18418%0.176CC..G310 helixtrans-68-15.6-17757.30000113.5L272 G273 I275 W307 D311T270-L272 PolarHBondContact O-N 3.21Å; T270-G273 CarbonylContact C-O 3.45Å; T270-I275 HydrophobicContact CG2-CD1 4.27Å; T270-I275 HydrophobicContact CG2-CG1 4.5Å; T270-I275 HydrophobicContact CG2-CG2 4.35Å; T270-W307 HydrophobicContact CG2-CG 4.45Å; T270-D311 HydrophobicContact CG2-CB 3.9Å
271S95Very high96.2Very high70 Ų7028.3 Ų28.349%0.4916%0.161SC..G310 helixtrans-81.41.4170.1630000113.7Y269Y269-S271 PolarHBondContact O-N 2.87Å
272L96.8Very high96.5Very high4 Ų425.1 Ų25.12%0.02114%0.138CC..G310 helixtrans-117.427.8-174-53177.2000111.4P226 I229 W230 L233 I252 N254 Y269 T270P226-L272 HydrophobicContact CB-CD1 3.75Å; P226-L272 WeakPolarHBondContact O-CD1 3.21Å; I229-L272 HydrophobicContact CB-CD1 4.02Å; I229-L272 HydrophobicContact CG2-CD1 4.02Å; W230-L272 HydrophobicContact CB-CD2 3.75Å; W230-L272 HydrophobicContact CD2-CD2 4.39Å; W230-L272 HydrophobicContact CE3-CD2 3.84Å; W230-L272 HydrophobicContact CG-CD2 4.4Å; L233-L272 HydrophobicContact CD1-CB 4.03Å; L233-L272 HydrophobicContact CD1-CD2 4.48Å; I252-L272 WeakPolarHBondContact CG2-O 3.19Å; N254-L272 PolarHBondContact ND2-O 3.46Å; Y269-L272 HydrophobicContact CD1-CD1 4.17Å; Y269-L272 WeakPolarHBondContact O-CB 3.43Å; Y269-L272 PolarHBondContact O-N 2.81Å; T270-L272 PolarHBondContact O-N 3.21Å
273G97.4Very high96.7Very high0 Ų024.2 Ų24.20%013%0.134CC..SBendtrans95.2-164.4-164.200000111.6D26 T270D26-G273 WeakPolarHBondContact OD1-CA 3.4Å; T270-G273 CarbonylContact C-O 3.45Å
274R97.9Very high96.8Very high30 Ų3022.5 Ų22.511%0.11312%0.12CC..EExtended strand (participates in β ladder)trans-77.7171.6-178.5-60-169.1-178.3-116.6-9.5112.4D26 F251 I252 V253 N254 D309 H310 D311 V312 I354D26-R274 HydrophobicContact CB-CG 4.4Å; D26-R274 PolarHBondContact O-NE 3.48Å; D26-R274 PolarHBondContact O-NH2 2.72Å; D26-R274 PolarHBondContact OD1-N 2.96Å; F251-R274 HydrophobicContact CE2-CG 4.05Å; F251-R274 HydrophobicContact CZ-CG 4.46Å; I252-R274 PolarHBondContact O-N 2.83Å; V253-R274 CarbonylContact C-O 3.56Å; V253-R274 WeakPolarHBondContact CA-O 3.24Å; V253-R274 HydrophobicContact CB-CB 4.34Å; V253-R274 HydrophobicContact CG2-CB 4.25Å; N254-R274 PolarHBondContact N-O 2.91Å; N254-R274 PolarHBondContact ND2-O 2.93Å; N254-R274 VanDerWaalsContact ND2-O 3.13Å; R274-D309 PolarHBondContact NH1-O 2.01Å; R274-D309 VanDerWaalsContact NH1-O 3.12Å; R274-H310 PolarHBondContact NE-O 2.84Å; R274-H310 PolarHBondContact NH1-O 3.48Å; R274-H310 VanDerWaalsContact NH1-O 3.09Å; R274-H310 PolarHBondContact NH2-O 2.65Å; R274-D311 CarbonylContact C-O 3.41Å; R274-D311 WeakPolarHBondContact CA-O 3.39Å; R274-D311 WeakPolarHBondContact CB-O 3.4Å; R274-V312 PolarHBondContact NH1-O 2.75Å; R274-V312 VanDerWaalsContact NH1-O 3.1Å; R274-I354 VanDerWaalsContact NE-CD1 3.33Å
275I98.3Very high96.8Very high1 Ų122.5 Ų22.51%0.00512%0.12CC..EExtended strand (participates in β ladder)trans-123.7154.7169.363.7171000111.7N254 V256 T270 N277 W307 D311 V312 L313N254-I275 HydrophobicContact CB-CG2 4.33Å; N254-I275 WeakPolarHBondContact O-CA 3.19Å; V256-I275 HydrophobicContact CG2-CG2 4.28Å; T270-I275 HydrophobicContact CG2-CD1 4.27Å; T270-I275 HydrophobicContact CG2-CG1 4.5Å; T270-I275 HydrophobicContact CG2-CG2 4.35Å; I275-N277 PolarHBondContact O-N 3.24Å; I275-W307 HydrophobicContact CD1-CD2 3.44Å; I275-W307 VanDerWaalsContact CD1-CD2 3.44Å; I275-W307 VanDerWaalsContact CD1-CE2 3.5Å; I275-W307 HydrophobicContact CD1-CE3 3.73Å; I275-W307 HydrophobicContact CD1-CG 3.85Å; I275-W307 HydrophobicContact CD1-CH2 4.14Å; I275-W307 HydrophobicContact CD1-CZ2 3.88Å; I275-W307 HydrophobicContact CD1-CZ3 4.06Å; I275-D311 PolarHBondContact N-O 3.14Å; I275-V312 HydrophobicContact CG1-CG1 4.13Å; I275-V312 WeakPolarHBondContact O-CA 3.14Å; I275-L313 PolarHBondContact O-N 3.24Å
276T98.1Very high96.8Very high3 Ų319.8 Ų19.82%0.01811%0.111CC..EExtended strand (participates in β ladder)trans-75.2116168.650.70000111.2V253 N254 E255 V256 F278 F315V253-T276 HydrophobicContact CG2-CG2 3.98Å; N254-T276 PolarHBondContact O-N 3.11Å; N254-T276 PolarHBondContact O-OG1 3.07Å; E255-T276 WeakPolarHBondContact CA-OG1 3.04Å; V256-T276 PolarHBondContact N-OG1 2.95Å; T276-F278 PolarHBondContact O-N 2.93Å; T276-F278 VanDerWaalsContact OG1-CE2 3.23Å; T276-F278 WeakPolarHBondContact OG1-CE2 3.35Å; T276-F315 HydrophobicContact CG2-CE1 4.04Å
277N96.9Very high96.9Very high0 Ų019.8 Ų19.80%011%0.111CC..  trans-86.691.6178.9-174.9-11.9000111.8I275 R279 Y280 Y306 V312 L313 V314I275-N277 PolarHBondContact O-N 3.24Å; N277-R279 VanDerWaalsContact C-N 3.28Å; N277-R279 PolarHBondContact O-N 2.85Å; N277-R279 WeakPolarHBondContact OD1-CB 3.28Å; N277-R279 PolarHBondContact OD1-N 3.4Å; N277-R279 VanDerWaalsContact OD1-N 3.13Å; N277-Y280 WeakPolarHBondContact O-CB 3.37Å; N277-Y280 PolarHBondContact O-N 2.93Å; N277-Y280 PolarHBondContact OD1-N 2.89Å; N277-Y306 WeakPolarHBondContact ND2-CD2 3.48Å; N277-V312 HydrophobicContact CB-CB 4.3Å; N277-V312 HydrophobicContact CB-CG1 4.24Å; N277-L313 PolarHBondContact N-O 3.29Å; N277-V314 HydrophobicContact CB-CG1 4.26Å
278F95.3Very high97Very high6 Ų616.4 Ų16.43%0.0269%0.088CC..Hα-helixtrans-68-21.3178.4-79.7-95.4000114.3E255 I257 Q259 T276 Y280 F315 G326E255-F278 HydrophobicContact CG-CE2 3.96Å; E255-F278 HydrophobicContact CG-CZ 4.13Å; I257-F278 HydrophobicContact CB-CD2 4.39Å; I257-F278 HydrophobicContact CB-CE2 4.34Å; I257-F278 HydrophobicContact CD1-CZ 4.43Å; I257-F278 HydrophobicContact CG1-CD2 4.1Å; I257-F278 HydrophobicContact CG1-CE1 4.07Å; I257-F278 HydrophobicContact CG1-CE2 3.59Å; I257-F278 HydrophobicContact CG1-CZ 3.58Å; Q259-F278 HydrophobicContact CG-CB 4.27Å; T276-F278 PolarHBondContact O-N 2.93Å; T276-F278 VanDerWaalsContact OG1-CE2 3.23Å; T276-F278 WeakPolarHBondContact OG1-CE2 3.35Å; F278-Y280 VanDerWaalsContact C-N 3.32Å; F278-F315 HydrophobicContact CD1-CE2 4.23Å; F278-F315 HydrophobicContact CD1-CZ 4.02Å; F278-F315 HydrophobicContact CD2-CZ 4.22Å; F278-F315 HydrophobicContact CE1-CE2 4.26Å; F278-F315 AromaticContact CE1-CZ 3.95Å; F278-F315 HydrophobicContact CE1-CZ 3.95Å; F278-F315 HydrophobicContact CE2-CZ 4.17Å; F278-F315 HydrophobicContact CG-CZ 4.15Å; F278-F315 HydrophobicContact CZ-CZ 4.04Å; F278-G326 WeakPolarHBondContact CE1-O 3.3Å
279R95.2Very high97Very high56 Ų5615 Ų1521%0.2118%0.083CC..Hα-helixtrans-70.1-32.2176-64.9170.461.5-158.8-9.8111.7N277 L282 D283 W304 A305 Y306N277-R279 VanDerWaalsContact C-N 3.28Å; N277-R279 PolarHBondContact O-N 2.85Å; N277-R279 WeakPolarHBondContact OD1-CB 3.28Å; N277-R279 PolarHBondContact OD1-N 3.4Å; N277-R279 VanDerWaalsContact OD1-N 3.13Å; R279-L282 PolarHBondContact O-N 3.36Å; R279-D283 WeakPolarHBondContact O-CB 3.25Å; R279-D283 PolarHBondContact O-N 2.84Å; R279-W304 PolarHBondContact NH2-O 3.21Å; R279-A305 PolarHBondContact NH1-O 3.1Å; R279-Y306 HydrophobicContact CB-CD1 4.32Å; R279-Y306 HydrophobicContact CB-CE1 3.63Å; R279-Y306 PolarHBondContact O-OH 2.93Å
280Y96.9Very high96.9Very high0 Ų018.6 Ų18.60%010%0.099CC..Hα-helixtrans-57.1-54.9-177.8-172.9-83.7000112.3N277 F278 L282 D283 L284 F300 Y306 V314 M347 Y352N277-Y280 WeakPolarHBondContact O-CB 3.37Å; N277-Y280 PolarHBondContact O-N 2.93Å; N277-Y280 PolarHBondContact OD1-N 2.89Å; F278-Y280 VanDerWaalsContact C-N 3.32Å; Y280-L282 PolarHBondContact O-N 3.07Å; Y280-D283 PolarHBondContact O-N 3.46Å; Y280-L284 HydrophobicContact CE1-CD2 3.82Å; Y280-L284 WeakPolarHBondContact O-CB 3.32Å; Y280-L284 PolarHBondContact O-N 3.14Å; Y280-F300 HydrophobicContact CD1-CE1 4.37Å; Y280-F300 HydrophobicContact CD2-CD1 4.27Å; Y280-F300 AromaticContact CD2-CE1 3.58Å; Y280-F300 HydrophobicContact CD2-CE1 3.58Å; Y280-F300 HydrophobicContact CD2-CZ 4.03Å; Y280-F300 HydrophobicContact CE1-CE1 4.07Å; Y280-F300 AromaticContact CE2-CD1 3.66Å; Y280-F300 HydrophobicContact CE2-CD1 3.66Å; Y280-F300 AromaticContact CE2-CE1 3.22Å; Y280-F300 HydrophobicContact CE2-CE1 3.22Å; Y280-F300 HydrophobicContact CE2-CZ 4.13Å; Y280-F300 HydrophobicContact CG-CE1 4.15Å; Y280-F300 HydrophobicContact CG-CZ 4.34Å; Y280-F300 AromaticContact CZ-CE1 3.5Å; Y280-Y306 HydrophobicContact CD2-CE2 4.15Å; Y280-V314 HydrophobicContact CD1-CB 3.77Å; Y280-V314 HydrophobicContact CD1-CG1 4.35Å; Y280-V314 HydrophobicContact CD1-CG2 4.43Å; Y280-V314 HydrophobicContact CD2-CB 3.94Å; Y280-V314 HydrophobicContact CD2-CG1 3.62Å; Y280-V314 HydrophobicContact CE1-CB 4.03Å; Y280-V314 HydrophobicContact CE1-CG2 4.18Å; Y280-V314 HydrophobicContact CE2-CB 4.17Å; Y280-V314 HydrophobicContact CE2-CG1 4.05Å; Y280-V314 HydrophobicContact CE2-CG2 4.32Å; Y280-V314 HydrophobicContact CG-CB 3.72Å; Y280-V314 HydrophobicContact CG-CG1 3.79Å; Y280-M347 HydrophobicContact CE1-CB 4.03Å; Y280-M347 HydrophobicContact CE1-CG 3.72Å; Y280-M347 HydrophobicContact CE1-SD 4.02Å; Y280-M347 WeakPolarHBondContact OH-CA 3.49Å; Y280-Y352 AromaticContact CD2-CD1 3.82Å; Y280-Y352 HydrophobicContact CD2-CD1 3.82Å; Y280-Y352 HydrophobicContact CD2-CE1 4Å; Y280-Y352 AromaticContact CE2-CD1 3.68Å; Y280-Y352 HydrophobicContact CE2-CD1 3.68Å; Y280-Y352 HydrophobicContact CE2-CE1 4.33Å
281G96.8Very high96.9Very high1 Ų124.9 Ų24.91%0.0112%0.124CC..Hα-helixtrans-65.4-38.6-178.500000113.2S285 F315 V316G281-S285 WeakPolarHBondContact O-CB 3.23Å; G281-S285 PolarHBondContact O-N 3.32Å; G281-S285 PolarHBondContact O-OG 3.2Å; G281-F315 WeakPolarHBondContact CA-O 3.48Å; G281-F315 PolarHBondContact N-O 2.81Å; G281-V316 WeakPolarHBondContact CA-O 3.48Å
282L95.3Very high97Very high37 Ų3725 Ų2519%0.19412%0.116CC..Hα-helixtrans-61.1-49.7174.9-73.9172.6000111.7Q259 R279 Y280 S285 A286 G329 V331Q259-L282 HydrophobicContact CG-CD1 4.03Å; R279-L282 PolarHBondContact O-N 3.36Å; Y280-L282 PolarHBondContact O-N 3.07Å; L282-S285 PolarHBondContact O-N 2.8Å; L282-A286 WeakPolarHBondContact O-CB 3.38Å; L282-A286 PolarHBondContact O-N 3.06Å; L282-G329 WeakPolarHBondContact CD2-O 3.5Å; L282-V331 HydrophobicContact CD2-CG1 3.77Å; L282-V331 HydrophobicContact CG-CG1 4.22Å
283D96.5Very high97.1Very high24 Ų2426.3 Ų26.313%0.12812%0.123CC..Hα-helixtrans-68.7-40-177.9-77.8-7.1000111.3R279 Y280 S285 A286 G287 K292 Y297 F300 W304 Y306R279-D283 WeakPolarHBondContact O-CB 3.25Å; R279-D283 PolarHBondContact O-N 2.84Å; Y280-D283 PolarHBondContact O-N 3.46Å; D283-S285 VanDerWaalsContact C-N 3.35Å; D283-S285 PolarHBondContact O-N 3.07Å; D283-A286 WeakPolarHBondContact O-CB 3.42Å; D283-A286 PolarHBondContact O-N 2.94Å; D283-G287 PolarHBondContact O-N 3.26Å; D283-K292 HydrophobicContact CB-CD 4.42Å; D283-K292 WeakPolarHBondContact OD1-CE 3.44Å; D283-K292 IonicContact OD1-NZ 2.73Å; D283-K292 PolarHBondContact OD1-NZ 3.28Å; D283-K292 IonicContact OD2-NZ 3.72Å; D283-K292 PolarHBondContact OD2-NZ 2.68Å; D283-Y297 PolarHBondContact O-OH 2.96Å; D283-F300 HydrophobicContact CB-CE2 3.82Å; D283-F300 HydrophobicContact CB-CZ 4.13Å; D283-W304 HydrophobicContact CB-CE3 4.49Å; D283-W304 HydrophobicContact CB-CZ3 4.12Å; D283-W304 WeakPolarHBondContact OD2-CZ3 3.41Å; D283-Y306 VanDerWaalsContact CB-OH 3.31Å; D283-Y306 WeakPolarHBondContact CB-OH 3.32Å; D283-Y306 VanDerWaalsContact CG-OH 3.28Å; D283-Y306 PolarHBondContact OD2-OH 3.5Å
284L97.6Very high97.1Very high0 Ų026.3 Ų26.30%012%0.123CC..Hα-helixtrans-64.5-41.2176-170.550.5000111.9Y280 G287 V288 F294 Y297 F300 V316 A343 F346 M347Y280-L284 HydrophobicContact CE1-CD2 3.82Å; Y280-L284 WeakPolarHBondContact O-CB 3.32Å; Y280-L284 PolarHBondContact O-N 3.14Å; L284-G287 PolarHBondContact O-N 2.77Å; L284-V288 PolarHBondContact O-N 2.91Å; L284-V288 VanDerWaalsContact O-N 3.1Å; L284-F294 HydrophobicContact CD1-CE1 3.98Å; L284-F294 HydrophobicContact CD1-CZ 4.14Å; L284-Y297 HydrophobicContact CD1-CD1 4.48Å; L284-Y297 HydrophobicContact CD1-CE1 4.02Å; L284-F300 HydrophobicContact CB-CE1 4.42Å; L284-F300 HydrophobicContact CB-CZ 4.16Å; L284-V316 HydrophobicContact CD2-CG2 4.2Å; L284-A343 HydrophobicContact CD2-CB 4.15Å; L284-A343 VanDerWaalsContact CD2-O 3.29Å; L284-A343 WeakPolarHBondContact CD2-O 3.38Å; L284-A343 HydrophobicContact CG-CB 3.9Å; L284-F346 HydrophobicContact CD1-CB 4.14Å; L284-F346 HydrophobicContact CD1-CD1 3.56Å; L284-F346 HydrophobicContact CD1-CE1 4.27Å; L284-F346 HydrophobicContact CD1-CG 3.98Å; L284-F346 HydrophobicContact CD2-CD1 4.14Å; L284-M347 HydrophobicContact CD2-CB 4.12Å
285S97.9Very high97.1Very high0 Ų028.5 Ų28.50%014%0.135CC..Hα-helixtrans-64-39.4174.3-59.80000112.2G281 L282 D283 G287 V288 N289 S330 V331 L332G281-S285 WeakPolarHBondContact O-CB 3.23Å; G281-S285 PolarHBondContact O-N 3.32Å; G281-S285 PolarHBondContact O-OG 3.2Å; L282-S285 PolarHBondContact O-N 2.8Å; D283-S285 VanDerWaalsContact C-N 3.35Å; D283-S285 PolarHBondContact O-N 3.07Å; S285-G287 VanDerWaalsContact C-N 3.31Å; S285-G287 PolarHBondContact O-N 3.37Å; S285-V288 PolarHBondContact O-N 3.31Å; S285-N289 WeakPolarHBondContact O-CB 3.34Å; S285-N289 PolarHBondContact O-N 2.95Å; S285-N289 PolarHBondContact O-ND2 3.13Å; S285-S330 WeakPolarHBondContact CB-O 3.21Å; S285-V331 WeakPolarHBondContact OG-CA 3.46Å; S285-L332 PolarHBondContact OG-N 3.23Å
286A97.2Very high97.1Very high15 Ų1533.7 Ų33.712%0.12416%0.159CC..Hα-helixtrans-62.7-37.6173.800000112.1L282 D283 H290 F291 K292L282-A286 WeakPolarHBondContact O-CB 3.38Å; L282-A286 PolarHBondContact O-N 3.06Å; D283-A286 WeakPolarHBondContact O-CB 3.42Å; D283-A286 PolarHBondContact O-N 2.94Å; A286-H290 PolarHBondContact O-N 3.13Å; A286-H290 VanDerWaalsContact O-N 3.16Å; A286-F291 HydrophobicContact CB-CB 4.05Å; A286-F291 WeakPolarHBondContact O-CA 3.19Å; A286-F291 PolarHBondContact O-N 3.49Å; A286-K292 HydrophobicContact CB-CB 4.29Å; A286-K292 HydrophobicContact CB-CD 4.1Å; A286-K292 HydrophobicContact CB-CG 3.86Å; A286-K292 PolarHBondContact O-N 2.92Å
287G98Very high97.1Very high0 Ų033.6 Ų33.60%016%0.158CC..Hα-helixtrans-62.6-49.8174.500000112.6D283 L284 S285 N289 H290 K292 Y297 N462D283-G287 PolarHBondContact O-N 3.26Å; L284-G287 PolarHBondContact O-N 2.77Å; S285-G287 VanDerWaalsContact C-N 3.31Å; S285-G287 PolarHBondContact O-N 3.37Å; G287-N289 VanDerWaalsContact C-N 3.34Å; G287-N289 PolarHBondContact O-N 3.38Å; G287-H290 PolarHBondContact O-N 2.78Å; G287-K292 WeakPolarHBondContact CA-O 3.36Å; G287-Y297 VanDerWaalsContact CA-OH 3.26Å; G287-Y297 WeakPolarHBondContact CA-OH 3.23Å; G287-Y297 PolarHBondContact N-OH 3.24Å; G287-N462 PolarHBondContact O-ND2 3.17Å
288V98.2Very high97.1Very high0 Ų034.8 Ų34.80%017%0.171CC..Hα-helixtrans-64.7-38.1178.41760000111.8L284 S285 H290 F294 L332 R339 M342 A343 N462L284-V288 PolarHBondContact O-N 2.91Å; L284-V288 VanDerWaalsContact O-N 3.1Å; S285-V288 PolarHBondContact O-N 3.31Å; V288-H290 PolarHBondContact O-N 3.08Å; V288-F294 HydrophobicContact CG2-CE2 4Å; V288-F294 HydrophobicContact CG2-CZ 3.78Å; V288-L332 HydrophobicContact CB-CD1 3.56Å; V288-L332 HydrophobicContact CG1-CD1 3.57Å; V288-L332 HydrophobicContact CG2-CD1 4.01Å; V288-R339 HydrophobicContact CG1-CB 3.73Å; V288-R339 HydrophobicContact CG1-CG 3.97Å; V288-M342 HydrophobicContact CG1-SD 4.28Å; V288-M342 HydrophobicContact CG2-CB 4.42Å; V288-M342 HydrophobicContact CG2-CG 4.18Å; V288-M342 HydrophobicContact CG2-SD 4.11Å; V288-A343 HydrophobicContact CG2-CB 4.18Å; V288-N462 WeakPolarHBondContact CA-ND2 3.12Å; V288-N462 PolarHBondContact O-ND2 2.66Å; V288-N462 PolarHBondContact O-OD1 3.21Å
289N97.2Very high97.1Very high39 Ų3938.4 Ų38.421%0.20919%0.191CC..THydrogen-bonded Turntrans-80.96.7177-70.9-38000114.3S285 G287 F291 R339S285-N289 WeakPolarHBondContact O-CB 3.34Å; S285-N289 PolarHBondContact O-N 2.95Å; S285-N289 PolarHBondContact O-ND2 3.13Å; G287-N289 VanDerWaalsContact C-N 3.34Å; G287-N289 PolarHBondContact O-N 3.38Å; N289-F291 VanDerWaalsContact C-N 3.25Å; N289-F291 HydrophobicContact CB-CD2 3.85Å; N289-F291 HydrophobicContact CB-CE2 3.76Å; N289-F291 HydrophobicContact CB-CZ 4.44Å; N289-F291 PolarHBondContact O-N 3.38Å; N289-R339 PolarHBondContact OD1-NH1 2.99Å
290H96.6Very high97.3Very high75 Ų7535.9 Ų35.935%0.34718%0.181SC..THydrogen-bonded Turntrans64.617.9179.5-51.1-80.2000115.9A286 G287 V288 N446 N462 R514A286-H290 PolarHBondContact O-N 3.13Å; A286-H290 VanDerWaalsContact O-N 3.16Å; G287-H290 PolarHBondContact O-N 2.78Å; V288-H290 PolarHBondContact O-N 3.08Å; H290-N446 PolarHBondContact ND1-OD1 3.07Å; H290-N462 PolarHBondContact CE1-ND2 2.72Å; H290-N462 PolarHBondContact CE1-O 3.39Å; H290-R514 PolarHBondContact NE2-NH1 3.03Å; H290-R514 PolarHBondContact NE2-NH2 3.1Å
291F96.4Very high97.3Very high161 Ų16136 Ų3671%0.70618%0.182SC*.SBendtrans-79.8-24.6167.2-55.7-45.6000111.9A286 N289A286-F291 HydrophobicContact CB-CB 4.05Å; A286-F291 WeakPolarHBondContact O-CA 3.19Å; A286-F291 PolarHBondContact O-N 3.49Å; N289-F291 VanDerWaalsContact C-N 3.25Å; N289-F291 HydrophobicContact CB-CD2 3.85Å; N289-F291 HydrophobicContact CB-CE2 3.76Å; N289-F291 HydrophobicContact CB-CZ 4.44Å; N289-F291 PolarHBondContact O-N 3.38Å
292K96.9Very high97.3Very high74 Ų7441.3 Ų41.332%0.32221%0.206SC..SBendtrans-124.1165.6166.4-65.2-171.1-179.9-164.50109.1D283 A286 G287 Y297 W304D283-K292 HydrophobicContact CB-CD 4.42Å; D283-K292 WeakPolarHBondContact OD1-CE 3.44Å; D283-K292 IonicContact OD1-NZ 2.73Å; D283-K292 PolarHBondContact OD1-NZ 3.28Å; D283-K292 IonicContact OD2-NZ 3.72Å; D283-K292 PolarHBondContact OD2-NZ 2.68Å; A286-K292 HydrophobicContact CB-CB 4.29Å; A286-K292 HydrophobicContact CB-CD 4.1Å; A286-K292 HydrophobicContact CB-CG 3.86Å; A286-K292 PolarHBondContact O-N 2.92Å; G287-K292 WeakPolarHBondContact CA-O 3.36Å; K292-Y297 HydrophobicContact CB-CE2 4.2Å; K292-Y297 WeakPolarHBondContact CB-OH 3.47Å; K292-W304 HydrophobicContact CD-CH2 3.99Å; K292-W304 HydrophobicContact CD-CZ3 3.75Å
293N97.9Very high97.4Very high31 Ų3141.9 Ų41.917%0.16622%0.221CC..  trans-116.6125.1-175.2-164.7-38.9000110.9M295 H296 Y297 D445 N446N293-M295 HydrophobicContact CB-CG 4.03Å; N293-M295 PolarHBondContact O-N 3.48Å; N293-M295 WeakPolarHBondContact OD1-CB 3.26Å; N293-M295 WeakPolarHBondContact OD1-CG 3.35Å; N293-M295 PolarHBondContact OD1-N 3.43Å; N293-H296 PolarHBondContact O-N 3.31Å; N293-Y297 VanDerWaalsContact O-CD2 3.26Å; N293-Y297 WeakPolarHBondContact O-CD2 3.21Å; N293-Y297 WeakPolarHBondContact O-CE2 3.44Å; N293-D445 PolarHBondContact ND2-OD1 2.93Å; N293-N446 WeakPolarHBondContact OD1-CA 3.34Å; N293-N446 PolarHBondContact OD1-N 3.35Å
294F98Very high97.4Very high0 Ų042.8 Ų42.80%022%0.223CC..G310 helixtrans-55.4-19176.5-82.6-74.1000113.8L284 V288 H296 Y297 M342 F346 I448 L460 N462L284-F294 HydrophobicContact CD1-CE1 3.98Å; L284-F294 HydrophobicContact CD1-CZ 4.14Å; V288-F294 HydrophobicContact CG2-CE2 4Å; V288-F294 HydrophobicContact CG2-CZ 3.78Å; F294-H296 PolarHBondContact O-N 3.4Å; F294-Y297 AromaticContact CD1-CD1 3.93Å; F294-Y297 HydrophobicContact CD1-CD1 3.93Å; F294-Y297 HydrophobicContact CD1-CD2 4.26Å; F294-Y297 HydrophobicContact CD1-CE1 4.34Å; F294-Y297 AromaticContact CD1-CG 3.89Å; F294-Y297 HydrophobicContact CD1-CG 3.89Å; F294-Y297 AromaticContact CE1-CD1 4Å; F294-Y297 HydrophobicContact CE1-CD1 4Å; F294-Y297 HydrophobicContact CE1-CE1 4.15Å; F294-Y297 HydrophobicContact CE1-CG 4.43Å; F294-Y297 PolarHBondContact O-N 3.38Å; F294-Y297 VanDerWaalsContact O-N 3.08Å; F294-M342 HydrophobicContact CE2-SD 4.42Å; F294-F346 HydrophobicContact CD1-CD2 4.44Å; F294-F346 HydrophobicContact CD1-CE2 4.41Å; F294-F346 HydrophobicContact CE1-CD2 4.02Å; F294-F346 HydrophobicContact CE1-CE2 4.35Å; F294-F346 HydrophobicContact CE1-CG 4.25Å; F294-I448 HydrophobicContact CB-CG2 4.26Å; F294-I448 HydrophobicContact CD1-CG2 4.03Å; F294-I448 HydrophobicContact CG-CG2 4.44Å; F294-L460 HydrophobicContact CD1-CD2 4.16Å; F294-L460 HydrophobicContact CD2-CD2 3.71Å; F294-L460 HydrophobicContact CE1-CD1 3.95Å; F294-L460 HydrophobicContact CE1-CD2 4.23Å; F294-L460 HydrophobicContact CE2-CD1 4.41Å; F294-L460 HydrophobicContact CE2-CD2 3.79Å; F294-L460 HydrophobicContact CG-CD2 3.9Å; F294-L460 HydrophobicContact CZ-CD1 3.89Å; F294-L460 HydrophobicContact CZ-CD2 4.05Å; F294-N462 HydrophobicContact CD2-CB 3.67Å; F294-N462 HydrophobicContact CE2-CB 3.79Å
295M97.6Very high97.3Very high76 Ų7646.4 Ų46.437%0.37425%0.253SS..G310 helixtrans-58.6-22.1174.578.8-178.2-74.700113.9N293 T443 E444N293-M295 HydrophobicContact CB-CG 4.03Å; N293-M295 PolarHBondContact O-N 3.48Å; N293-M295 WeakPolarHBondContact OD1-CB 3.26Å; N293-M295 WeakPolarHBondContact OD1-CG 3.35Å; N293-M295 PolarHBondContact OD1-N 3.43Å; M295-T443 WeakPolarHBondContact O-CB 3.47Å; M295-T443 PolarHBondContact O-OG1 3.02Å; M295-E444 VanDerWaalsContact CB-O 3.23Å; M295-E444 WeakPolarHBondContact CB-O 3.45Å
296H97.7Very high97.2Very high110 Ų11047.1 Ų47.151%0.50926%0.256SS..G310 helixtrans-100.43.1-178.9-57.3-54.5000113.8N293 F294 G298 N299 W304N293-H296 PolarHBondContact O-N 3.31Å; F294-H296 PolarHBondContact O-N 3.4Å; H296-G298 VanDerWaalsContact C-N 3.25Å; H296-G298 PolarHBondContact O-N 2.92Å; H296-N299 PolarHBondContact O-OD1 3.26Å; H296-W304 HydrophobicContact CB-CZ2 4.28Å; H296-W304 WeakPolarHBondContact O-CZ2 3.16Å; H296-W304 PolarHBondContact O-NE1 3.35Å
297Y98.1Very high97.2Very high0 Ų048.1 Ų48.10%026%0.256CS..G310 helixtrans-86.13.6-173.7-78.7-124.4000112.8D283 L284 G287 K292 N293 F294 N299 F300 W304 F346D283-Y297 PolarHBondContact O-OH 2.96Å; L284-Y297 HydrophobicContact CD1-CD1 4.48Å; L284-Y297 HydrophobicContact CD1-CE1 4.02Å; G287-Y297 VanDerWaalsContact CA-OH 3.26Å; G287-Y297 WeakPolarHBondContact CA-OH 3.23Å; G287-Y297 PolarHBondContact N-OH 3.24Å; K292-Y297 HydrophobicContact CB-CE2 4.2Å; K292-Y297 WeakPolarHBondContact CB-OH 3.47Å; N293-Y297 VanDerWaalsContact O-CD2 3.26Å; N293-Y297 WeakPolarHBondContact O-CD2 3.21Å; N293-Y297 WeakPolarHBondContact O-CE2 3.44Å; F294-Y297 AromaticContact CD1-CD1 3.93Å; F294-Y297 HydrophobicContact CD1-CD1 3.93Å; F294-Y297 HydrophobicContact CD1-CD2 4.26Å; F294-Y297 HydrophobicContact CD1-CE1 4.34Å; F294-Y297 AromaticContact CD1-CG 3.89Å; F294-Y297 HydrophobicContact CD1-CG 3.89Å; F294-Y297 AromaticContact CE1-CD1 4Å; F294-Y297 HydrophobicContact CE1-CD1 4Å; F294-Y297 HydrophobicContact CE1-CE1 4.15Å; F294-Y297 HydrophobicContact CE1-CG 4.43Å; F294-Y297 PolarHBondContact O-N 3.38Å; F294-Y297 VanDerWaalsContact O-N 3.08Å; Y297-N299 PolarHBondContact O-N 3.28Å; Y297-F300 HydrophobicContact CD1-CB 4.27Å; Y297-F300 HydrophobicContact CD1-CD1 4.3Å; Y297-F300 AromaticContact CD1-CD2 3.8Å; Y297-F300 HydrophobicContact CD1-CD2 3.8Å; Y297-F300 HydrophobicContact CD1-CE2 4.15Å; Y297-F300 AromaticContact CD1-CG 3.89Å; Y297-F300 HydrophobicContact CD1-CG 3.89Å; Y297-F300 HydrophobicContact CD1-CZ 4.5Å; Y297-F300 AromaticContact CE1-CD2 3.93Å; Y297-F300 HydrophobicContact CE1-CD2 3.93Å; Y297-F300 AromaticContact CE1-CE2 3.8Å; Y297-F300 HydrophobicContact CE1-CE2 3.8Å; Y297-F300 HydrophobicContact CE1-CG 4.37Å; Y297-F300 HydrophobicContact CE1-CZ 4.1Å; Y297-F300 HydrophobicContact CG-CD2 4.45Å; Y297-F300 VanDerWaalsContact O-CB 3.3Å; Y297-F300 WeakPolarHBondContact O-CB 3.49Å; Y297-F300 PolarHBondContact O-N 3.22Å; Y297-W304 AromaticContact CD2-CH2 3.98Å; Y297-W304 HydrophobicContact CD2-CH2 3.98Å; Y297-W304 AromaticContact CD2-CZ2 3.83Å; Y297-W304 HydrophobicContact CD2-CZ2 3.83Å; Y297-W304 AromaticContact CE2-CH2 3.55Å; Y297-W304 HydrophobicContact CE2-CH2 3.55Å; Y297-W304 AromaticContact CE2-CZ2 3.91Å; Y297-W304 HydrophobicContact CE2-CZ2 3.91Å; Y297-W304 HydrophobicContact CG-CZ2 4.32Å; Y297-W304 AromaticContact CZ-CH2 3.86Å; Y297-F346 HydrophobicContact CD1-CE1 4.1Å; Y297-F346 HydrophobicContact CD1-CZ 4.04Å
298G96.9Very high97.1Very high25 Ų2549.3 Ų49.326%0.25827%0.266SS..G310 helixtrans-66.4-6.4-177.500000115.7H296 W350 M441H296-G298 VanDerWaalsContact C-N 3.25Å; H296-G298 PolarHBondContact O-N 2.92Å; G298-W350 WeakPolarHBondContact O-CH2 3.06Å; G298-M441 WeakPolarHBondContact CA-SD 3.42Å
299N96.8Very high97Very high83 Ų8352.6 Ų52.644%0.44428%0.284SS..G310 helixtrans-134.726.6171.868.2-19.2000111.8H296 Y297 G301 G303 W304H296-N299 PolarHBondContact O-OD1 3.26Å; Y297-N299 PolarHBondContact O-N 3.28Å; N299-G301 PolarHBondContact O-N 2.76Å; N299-G303 PolarHBondContact ND2-O 3.22Å; N299-G303 WeakPolarHBondContact O-CA 2.99Å; N299-G303 PolarHBondContact O-N 2.96Å; N299-W304 VanDerWaalsContact O-CD1 3.3Å; N299-W304 VanDerWaalsContact OD1-CD1 3.31Å; N299-W304 PolarHBondContact OD1-NE1 2.66Å
300F98Very high96.9Very high3 Ų355.7 Ų55.71%0.01330%0.297CS..THydrogen-bonded Turntrans-56.6122.7-178.8-168.3-120.3000110.5Y280 D283 L284 Y297 W304 Y306 F346 W350Y280-F300 HydrophobicContact CD1-CE1 4.37Å; Y280-F300 HydrophobicContact CD2-CD1 4.27Å; Y280-F300 AromaticContact CD2-CE1 3.58Å; Y280-F300 HydrophobicContact CD2-CE1 3.58Å; Y280-F300 HydrophobicContact CD2-CZ 4.03Å; Y280-F300 HydrophobicContact CE1-CE1 4.07Å; Y280-F300 AromaticContact CE2-CD1 3.66Å; Y280-F300 HydrophobicContact CE2-CD1 3.66Å; Y280-F300 AromaticContact CE2-CE1 3.22Å; Y280-F300 HydrophobicContact CE2-CE1 3.22Å; Y280-F300 HydrophobicContact CE2-CZ 4.13Å; Y280-F300 HydrophobicContact CG-CE1 4.15Å; Y280-F300 HydrophobicContact CG-CZ 4.34Å; Y280-F300 AromaticContact CZ-CE1 3.5Å; D283-F300 HydrophobicContact CB-CE2 3.82Å; D283-F300 HydrophobicContact CB-CZ 4.13Å; L284-F300 HydrophobicContact CB-CE1 4.42Å; L284-F300 HydrophobicContact CB-CZ 4.16Å; Y297-F300 HydrophobicContact CD1-CB 4.27Å; Y297-F300 HydrophobicContact CD1-CD1 4.3Å; Y297-F300 AromaticContact CD1-CD2 3.8Å; Y297-F300 HydrophobicContact CD1-CD2 3.8Å; Y297-F300 HydrophobicContact CD1-CE2 4.15Å; Y297-F300 AromaticContact CD1-CG 3.89Å; Y297-F300 HydrophobicContact CD1-CG 3.89Å; Y297-F300 HydrophobicContact CD1-CZ 4.5Å; Y297-F300 AromaticContact CE1-CD2 3.93Å; Y297-F300 HydrophobicContact CE1-CD2 3.93Å; Y297-F300 AromaticContact CE1-CE2 3.8Å; Y297-F300 HydrophobicContact CE1-CE2 3.8Å; Y297-F300 HydrophobicContact CE1-CG 4.37Å; Y297-F300 HydrophobicContact CE1-CZ 4.1Å; Y297-F300 HydrophobicContact CG-CD2 4.45Å; Y297-F300 VanDerWaalsContact O-CB 3.3Å; Y297-F300 WeakPolarHBondContact O-CB 3.49Å; Y297-F300 PolarHBondContact O-N 3.22Å; F300-W304 AromaticContact CD2-CD2 3.79Å; F300-W304 HydrophobicContact CD2-CD2 3.79Å; F300-W304 AromaticContact CD2-CE2 3.86Å; F300-W304 HydrophobicContact CD2-CE3 4Å; F300-W304 HydrophobicContact CD2-CG 4.22Å; F300-W304 HydrophobicContact CD2-CH2 4.36Å; F300-W304 HydrophobicContact CD2-CZ2 4.17Å; F300-W304 HydrophobicContact CD2-CZ3 4.27Å; F300-W304 HydrophobicContact CE2-CD2 4.29Å; F300-W304 HydrophobicContact CE2-CE3 4.03Å; F300-W304 HydrophobicContact CE2-CZ3 4.15Å; F300-Y306 HydrophobicContact CD2-CE2 4.49Å; F300-Y306 HydrophobicContact CE2-CE2 4.11Å; F300-Y306 HydrophobicContact CZ-CE2 4.31Å; F300-F346 AromaticContact CD1-CE1 3.67Å; F300-F346 HydrophobicContact CD1-CE1 3.67Å; F300-F346 HydrophobicContact CD1-CZ 4.48Å; F300-F346 HydrophobicContact CE1-CE1 4.19Å; F300-F346 HydrophobicContact CG-CE1 4.35Å; F300-W350 HydrophobicContact CB-CZ2 4.41Å; F300-W350 PolarHBondContact O-NE1 3.06Å
301G97.5Very high96.9Very high1 Ų153.1 Ų53.11%0.0129%0.285CS..THydrogen-bonded Turntrans128.4-136.2-165.100000111.1N299 G303 W304 Y306N299-G301 PolarHBondContact O-N 2.76Å; G301-G303 PolarHBondContact O-N 3.06Å; G301-G303 VanDerWaalsContact O-N 3.16Å; G301-W304 WeakPolarHBondContact O-CA 3.33Å; G301-W304 WeakPolarHBondContact O-CB 3.3Å; G301-W304 PolarHBondContact O-N 2.8Å; G301-Y306 WeakPolarHBondContact O-CB 3.49Å; G301-Y306 WeakPolarHBondContact O-CD2 3.29Å
302E96.8Very high97Very high113 Ų11345.5 Ų45.553%0.52825%0.252SS..G310 helixtrans-54.1-34.8178.3-67.1179.5-153.400113.3W304 A305 W307 A308 D309 Y352E302-W304 PolarHBondContact O-N 3.17Å; E302-A305 WeakPolarHBondContact O-CA 3.41Å; E302-A305 PolarHBondContact O-N 3.26Å; E302-W307 WeakPolarHBondContact CG-O 3.34Å; E302-A308 VanDerWaalsContact OE1-CA 3.28Å; E302-A308 WeakPolarHBondContact OE1-CA 3.39Å; E302-D309 PolarHBondContact OE1-N 2.89Å; E302-Y352 HydrophobicContact CG-CE2 4.26Å
303G96.8Very high97Very high49 Ų4942 Ų4251%0.50524%0.237SC..G310 helixtrans-63.3-13.2175.800000114.5N299 G301N299-G303 PolarHBondContact ND2-O 3.22Å; N299-G303 WeakPolarHBondContact O-CA 2.99Å; N299-G303 PolarHBondContact O-N 2.96Å; G301-G303 PolarHBondContact O-N 3.06Å; G301-G303 VanDerWaalsContact O-N 3.16Å
304W96.5Very high97.1Very high44 Ų4440.5 Ų40.517%0.16723%0.229CC..G310 helixtrans-102.518.4175.2-73.549.1000112.1R279 D283 K292 H296 Y297 N299 F300 G301 E302 Y306R279-W304 PolarHBondContact NH2-O 3.21Å; D283-W304 HydrophobicContact CB-CE3 4.49Å; D283-W304 HydrophobicContact CB-CZ3 4.12Å; D283-W304 WeakPolarHBondContact OD2-CZ3 3.41Å; K292-W304 HydrophobicContact CD-CH2 3.99Å; K292-W304 HydrophobicContact CD-CZ3 3.75Å; H296-W304 HydrophobicContact CB-CZ2 4.28Å; H296-W304 WeakPolarHBondContact O-CZ2 3.16Å; H296-W304 PolarHBondContact O-NE1 3.35Å; Y297-W304 AromaticContact CD2-CH2 3.98Å; Y297-W304 HydrophobicContact CD2-CH2 3.98Å; Y297-W304 AromaticContact CD2-CZ2 3.83Å; Y297-W304 HydrophobicContact CD2-CZ2 3.83Å; Y297-W304 AromaticContact CE2-CH2 3.55Å; Y297-W304 HydrophobicContact CE2-CH2 3.55Å; Y297-W304 AromaticContact CE2-CZ2 3.91Å; Y297-W304 HydrophobicContact CE2-CZ2 3.91Å; Y297-W304 HydrophobicContact CG-CZ2 4.32Å; Y297-W304 AromaticContact CZ-CH2 3.86Å; N299-W304 VanDerWaalsContact O-CD1 3.3Å; N299-W304 VanDerWaalsContact OD1-CD1 3.31Å; N299-W304 PolarHBondContact OD1-NE1 2.66Å; F300-W304 AromaticContact CD2-CD2 3.79Å; F300-W304 HydrophobicContact CD2-CD2 3.79Å; F300-W304 AromaticContact CD2-CE2 3.86Å; F300-W304 HydrophobicContact CD2-CE3 4Å; F300-W304 HydrophobicContact CD2-CG 4.22Å; F300-W304 HydrophobicContact CD2-CH2 4.36Å; F300-W304 HydrophobicContact CD2-CZ2 4.17Å; F300-W304 HydrophobicContact CD2-CZ3 4.27Å; F300-W304 HydrophobicContact CE2-CD2 4.29Å; F300-W304 HydrophobicContact CE2-CE3 4.03Å; F300-W304 HydrophobicContact CE2-CZ3 4.15Å; G301-W304 WeakPolarHBondContact O-CA 3.33Å; G301-W304 WeakPolarHBondContact O-CB 3.3Å; G301-W304 PolarHBondContact O-N 2.8Å; E302-W304 PolarHBondContact O-N 3.17Å; W304-Y306 HydrophobicContact CB-CD1 4.33Å; W304-Y306 HydrophobicContact CB-CE1 4.16Å; W304-Y306 HydrophobicContact CB-CE2 4.37Å; W304-Y306 PolarHBondContact O-N 3.3Å
305A95.5Very high97.1Very high76 Ų7640.6 Ų40.663%0.62823%0.229SC*.THydrogen-bonded Turntrans54.939.6-173.900000112R279 E302R279-A305 PolarHBondContact NH1-O 3.1Å; E302-A305 WeakPolarHBondContact O-CA 3.41Å; E302-A305 PolarHBondContact O-N 3.26Å
306Y96.8Very high97.1Very high15 Ų1537 Ų376%0.05921%0.211CC..PPolyproline II helixtrans-84.4170.5160.9-57.9-18.1000109.8N277 R279 Y280 D283 F300 G301 W304 Y352N277-Y306 WeakPolarHBondContact ND2-CD2 3.48Å; R279-Y306 HydrophobicContact CB-CD1 4.32Å; R279-Y306 HydrophobicContact CB-CE1 3.63Å; R279-Y306 PolarHBondContact O-OH 2.93Å; Y280-Y306 HydrophobicContact CD2-CE2 4.15Å; D283-Y306 VanDerWaalsContact CB-OH 3.31Å; D283-Y306 WeakPolarHBondContact CB-OH 3.32Å; D283-Y306 VanDerWaalsContact CG-OH 3.28Å; D283-Y306 PolarHBondContact OD2-OH 3.5Å; F300-Y306 HydrophobicContact CD2-CE2 4.49Å; F300-Y306 HydrophobicContact CE2-CE2 4.11Å; F300-Y306 HydrophobicContact CZ-CE2 4.31Å; G301-Y306 WeakPolarHBondContact O-CB 3.49Å; G301-Y306 WeakPolarHBondContact O-CD2 3.29Å; W304-Y306 HydrophobicContact CB-CD1 4.33Å; W304-Y306 HydrophobicContact CB-CE1 4.16Å; W304-Y306 HydrophobicContact CB-CE2 4.37Å; W304-Y306 PolarHBondContact O-N 3.3Å; Y306-Y352 WeakPolarHBondContact CB-OH 3.39Å; Y306-Y352 AromaticContact CD2-CE1 3.86Å; Y306-Y352 HydrophobicContact CD2-CE1 3.86Å
307W97Very high97.1Very high36 Ų3631.8 Ų31.814%0.13619%0.187CC..PPolyproline II helixtrans-65.5168.4171.9-57.3-94.6000112.1D258 S267 T270 I275 E302 D311 V312 Y352D258-W307 HydrophobicContact CB-CH2 3.95Å; D258-W307 HydrophobicContact CB-CZ2 4.31Å; D258-W307 VanDerWaalsContact OD2-CZ2 3.32Å; D258-W307 WeakPolarHBondContact OD2-CZ2 3.32Å; S267-W307 VanDerWaalsContact N-NE1 3.1Å; T270-W307 HydrophobicContact CG2-CG 4.45Å; I275-W307 HydrophobicContact CD1-CD2 3.44Å; I275-W307 VanDerWaalsContact CD1-CD2 3.44Å; I275-W307 VanDerWaalsContact CD1-CE2 3.5Å; I275-W307 HydrophobicContact CD1-CE3 3.73Å; I275-W307 HydrophobicContact CD1-CG 3.85Å; I275-W307 HydrophobicContact CD1-CH2 4.14Å; I275-W307 HydrophobicContact CD1-CZ2 3.88Å; I275-W307 HydrophobicContact CD1-CZ3 4.06Å; E302-W307 WeakPolarHBondContact CG-O 3.34Å; W307-D311 HydrophobicContact CB-CB 4.05Å; W307-V312 HydrophobicContact CB-CG1 3.75Å; W307-V312 HydrophobicContact CE3-CG1 4.33Å; W307-V312 HydrophobicContact CG-CG1 4.49Å; W307-Y352 PolarHBondContact O-OH 2.93Å
308A96.8Very high97Very high24 Ų2431.9 Ų31.920%0.19819%0.188CC..PPolyproline II helixtrans-60.3151.7-179.400000111.2E302 H310 D311E302-A308 VanDerWaalsContact OE1-CA 3.28Å; E302-A308 WeakPolarHBondContact OE1-CA 3.39Å; A308-H310 VanDerWaalsContact CB-CE1 3.5Å; A308-H310 WeakPolarHBondContact CB-CE1 3.33Å; A308-H310 PolarHBondContact O-N 2.85Å; A308-D311 WeakPolarHBondContact CB-OD2 3.48Å; A308-D311 WeakPolarHBondContact O-CB 3.3Å; A308-D311 PolarHBondContact O-N 2.9Å
309D95.5Very high96.9Very high70 Ų7030.8 Ų30.837%0.37418%0.176SC..G310 helixtrans-50.3-40.4178.717566.8000113.6R274 E302 D311 Y352 G353R274-D309 PolarHBondContact NH1-O 2.01Å; R274-D309 VanDerWaalsContact NH1-O 3.12Å; E302-D309 PolarHBondContact OE1-N 2.89Å; D309-D311 VanDerWaalsContact C-N 3.28Å; D309-D311 PolarHBondContact O-N 3.34Å; D309-Y352 HydrophobicContact CB-CD2 4.22Å; D309-Y352 HydrophobicContact CB-CE2 4.43Å; D309-Y352 WeakPolarHBondContact OD1-CA 2.74Å; D309-G353 PolarHBondContact OD1-N 2.82Å
310H94.3Very high96.6Very high104 Ų10427.8 Ų27.848%0.48116%0.16SC..G310 helixtrans-75.4-12.5-179.767.3-86.6000114.2R274 A308R274-H310 PolarHBondContact NE-O 2.84Å; R274-H310 PolarHBondContact NH1-O 3.48Å; R274-H310 VanDerWaalsContact NH1-O 3.09Å; R274-H310 PolarHBondContact NH2-O 2.65Å; A308-H310 VanDerWaalsContact CB-CE1 3.5Å; A308-H310 WeakPolarHBondContact CB-CE1 3.33Å; A308-H310 PolarHBondContact O-N 2.85Å
311D96.7Very high96.2Very high21 Ų2128.2 Ų28.211%0.11216%0.162CC..G310 helixtrans-91.7-6.9-176.8-68.6-32000113.3T270 R274 I275 W307 A308 D309T270-D311 HydrophobicContact CG2-CB 3.9Å; R274-D311 CarbonylContact C-O 3.41Å; R274-D311 WeakPolarHBondContact CA-O 3.39Å; R274-D311 WeakPolarHBondContact CB-O 3.4Å; I275-D311 PolarHBondContact N-O 3.14Å; W307-D311 HydrophobicContact CB-CB 4.05Å; A308-D311 WeakPolarHBondContact CB-OD2 3.48Å; A308-D311 WeakPolarHBondContact O-CB 3.3Å; A308-D311 PolarHBondContact O-N 2.9Å; D309-D311 VanDerWaalsContact C-N 3.28Å; D309-D311 PolarHBondContact O-N 3.34Å
312V98.1Very high95.9Very high0 Ų028.2 Ų28.20%016%0.162CC..EExtended strand (participates in β ladder)trans-127144.6-164.3-61.70000115R274 I275 N277 W307 V314 Y352 G353 I354R274-V312 PolarHBondContact NH1-O 2.75Å; R274-V312 VanDerWaalsContact NH1-O 3.1Å; I275-V312 HydrophobicContact CG1-CG1 4.13Å; I275-V312 WeakPolarHBondContact O-CA 3.14Å; N277-V312 HydrophobicContact CB-CB 4.3Å; N277-V312 HydrophobicContact CB-CG1 4.24Å; W307-V312 HydrophobicContact CB-CG1 3.75Å; W307-V312 HydrophobicContact CE3-CG1 4.33Å; W307-V312 HydrophobicContact CG-CG1 4.49Å; V312-V314 HydrophobicContact CB-CG1 4.49Å; V312-V314 HydrophobicContact CG2-CG1 4.13Å; V312-Y352 HydrophobicContact CG2-CD1 4.42Å; V312-Y352 HydrophobicContact CG2-CE1 3.73Å; V312-Y352 HydrophobicContact CG2-CE2 4.17Å; V312-G353 WeakPolarHBondContact O-CA 3.02Å; V312-I354 PolarHBondContact O-N 3.36Å; V312-I354 VanDerWaalsContact O-N 3.1Å
313L98.6Very high95.5Very high1 Ų123 Ų231%0.00514%0.138CC..EExtended strand (participates in β ladder)trans-106.7131.3156.9-177.3156.9000107.8F251 V253 I275 N277 F315 I354 R356F251-L313 HydrophobicContact CE1-CD1 4.48Å; V253-L313 HydrophobicContact CB-CD1 4.43Å; V253-L313 HydrophobicContact CG1-CD1 4.13Å; V253-L313 HydrophobicContact CG2-CB 3.76Å; V253-L313 HydrophobicContact CG2-CD1 4.17Å; I275-L313 PolarHBondContact O-N 3.24Å; N277-L313 PolarHBondContact N-O 3.29Å; L313-F315 HydrophobicContact CD2-CD1 3.76Å; L313-F315 HydrophobicContact CD2-CE1 4.33Å; L313-I354 CarbonylContact C-O 3.45Å; L313-I354 WeakPolarHBondContact CA-O 3.39Å; L313-I354 HydrophobicContact CD1-CG2 4.46Å; L313-I354 HydrophobicContact CG-CB 4.45Å; L313-I354 HydrophobicContact CG-CG2 4.43Å; L313-I354 WeakPolarHBondContact CG-O 3.21Å; L313-R356 HydrophobicContact CD1-CB 4.48Å; L313-R356 HydrophobicContact CD2-CB 3.73Å; L313-R356 HydrophobicContact CG-CB 4.32Å
314V98.6Very high94.6Very high0 Ų022.3 Ų22.30%013%0.13CC..EExtended strand (participates in β ladder)trans-116.2151-176-610000111.1N277 Y280 V312 M347 Y352 I354 P355 R356N277-V314 HydrophobicContact CB-CG1 4.26Å; Y280-V314 HydrophobicContact CD1-CB 3.77Å; Y280-V314 HydrophobicContact CD1-CG1 4.35Å; Y280-V314 HydrophobicContact CD1-CG2 4.43Å; Y280-V314 HydrophobicContact CD2-CB 3.94Å; Y280-V314 HydrophobicContact CD2-CG1 3.62Å; Y280-V314 HydrophobicContact CE1-CB 4.03Å; Y280-V314 HydrophobicContact CE1-CG2 4.18Å; Y280-V314 HydrophobicContact CE2-CB 4.17Å; Y280-V314 HydrophobicContact CE2-CG1 4.05Å; Y280-V314 HydrophobicContact CE2-CG2 4.32Å; Y280-V314 HydrophobicContact CG-CB 3.72Å; Y280-V314 HydrophobicContact CG-CG1 3.79Å; V312-V314 HydrophobicContact CB-CG1 4.49Å; V312-V314 HydrophobicContact CG2-CG1 4.13Å; V314-M347 HydrophobicContact CG2-CG 4.2Å; V314-M347 HydrophobicContact CG2-SD 4.27Å; V314-Y352 HydrophobicContact CG1-CD1 3.85Å; V314-Y352 HydrophobicContact CG1-CE1 3.79Å; V314-Y352 WeakPolarHBondContact CG2-O 3.29Å; V314-I354 PolarHBondContact N-O 2.9Å; V314-P355 HydrophobicContact CG2-CB 4.29Å; V314-P355 CarbonylContact O-C 3.49Å; V314-P355 WeakPolarHBondContact O-CA 3.35Å; V314-R356 PolarHBondContact O-N 3.3Å
315F98.5Very high93.5Very high1 Ų122.3 Ų22.30%0.00414%0.137CC..  trans-155.3156.2177.449.9-90.7000109.8T276 F278 G281 L313 D317 N318 M347 R356T276-F315 HydrophobicContact CG2-CE1 4.04Å; F278-F315 HydrophobicContact CD1-CE2 4.23Å; F278-F315 HydrophobicContact CD1-CZ 4.02Å; F278-F315 HydrophobicContact CD2-CZ 4.22Å; F278-F315 HydrophobicContact CE1-CE2 4.26Å; F278-F315 AromaticContact CE1-CZ 3.95Å; F278-F315 HydrophobicContact CE1-CZ 3.95Å; F278-F315 HydrophobicContact CE2-CZ 4.17Å; F278-F315 HydrophobicContact CG-CZ 4.15Å; F278-F315 HydrophobicContact CZ-CZ 4.04Å; G281-F315 WeakPolarHBondContact CA-O 3.48Å; G281-F315 PolarHBondContact N-O 2.81Å; L313-F315 HydrophobicContact CD2-CD1 3.76Å; L313-F315 HydrophobicContact CD2-CE1 4.33Å; F315-D317 WeakPolarHBondContact CB-O 3.45Å; F315-D317 WeakPolarHBondContact CD2-O 3.26Å; F315-N318 HydrophobicContact CD2-CB 4.1Å; F315-N318 HydrophobicContact CE2-CB 3.95Å; F315-M347 VanDerWaalsContact CA-SD 3.54Å; F315-R356 WeakPolarHBondContact CB-O 3.28Å; F315-R356 VanDerWaalsContact CD1-NH2 3.28Å
316V98.3Very high92Very high1 Ų119.7 Ų19.71%0.00612%0.118CC..SBendtrans-75.6-47.8169.4179.30000109.3G281 L284 L332 Y340 A343 V344 M347G281-V316 WeakPolarHBondContact CA-O 3.48Å; L284-V316 HydrophobicContact CD2-CG2 4.2Å; V316-L332 HydrophobicContact CG1-CB 4.24Å; V316-Y340 HydrophobicContact CB-CE2 4.1Å; V316-Y340 HydrophobicContact CG1-CD2 3.91Å; V316-Y340 HydrophobicContact CG1-CE2 3.95Å; V316-A343 HydrophobicContact CG1-CB 3.8Å; V316-A343 HydrophobicContact CG2-CB 3.81Å; V316-V344 HydrophobicContact CB-CG2 4.44Å; V316-V344 HydrophobicContact CG2-CG2 3.89Å; V316-M347 HydrophobicContact CG2-CE 4.26Å; V316-M347 HydrophobicContact CG2-SD 4.17Å
317D97Very high90.2Very high1 Ų120.7 Ų20.71%0.00513%0.132CC..  trans-141169.7-178.164.1-21.4000111.6F315 N321 Q322 V331 T333 Y340F315-D317 WeakPolarHBondContact CB-O 3.45Å; F315-D317 WeakPolarHBondContact CD2-O 3.26Å; D317-N321 VanDerWaalsContact CA-OD1 3.29Å; D317-N321 WeakPolarHBondContact CA-OD1 3.45Å; D317-N321 WeakPolarHBondContact CB-OD1 3.49Å; D317-Q322 HydrophobicContact CB-CG 4.05Å; D317-Q322 VanDerWaalsContact OD2-CG 3.22Å; D317-Q322 WeakPolarHBondContact OD2-CG 3.5Å; D317-Q322 PolarHBondContact OD2-NE2 3.2Å; D317-V331 HydrophobicContact CB-CG2 4.43Å; D317-T333 HydrophobicContact CB-CG2 4.49Å; D317-Y340 WeakPolarHBondContact OD1-CE2 3.44Å; D317-Y340 PolarHBondContact OD1-OH 2.55Å
318N96.1Very high88.3Confident2 Ų220.5 Ų20.51%0.01114%0.141CC..  trans-143.9178.2174.374.4-1.7000109.5F315 D320 N321 Q322 R356F315-N318 HydrophobicContact CD2-CB 4.1Å; F315-N318 HydrophobicContact CE2-CB 3.95Å; N318-D320 VanDerWaalsContact C-N 3.27Å; N318-D320 PolarHBondContact O-N 3.37Å; N318-D320 PolarHBondContact OD1-N 3.37Å; N318-D320 VanDerWaalsContact OD1-N 3.15Å; N318-N321 PolarHBondContact N-OD1 2.58Å; N318-N321 PolarHBondContact O-OD1 3.48Å; N318-N321 WeakPolarHBondContact OD1-CB 3.32Å; N318-N321 PolarHBondContact OD1-N 2.65Å; N318-N321 PolarHBondContact OD1-ND2 2.87Å; N318-N321 PolarHBondContact OD1-OD1 3.28Å; N318-Q322 VanDerWaalsContact O-CB 3.3Å; N318-Q322 WeakPolarHBondContact O-CB 3.46Å; N318-Q322 WeakPolarHBondContact O-CG 3.31Å; N318-Q322 PolarHBondContact O-N 3.05Å; N318-Q322 VanDerWaalsContact O-N 3.1Å; N318-R356 VanDerWaalsContact CB-NH2 3.31Å
319H93.7Very high86.9Confident1 Ų121.1 Ų21.11%0.00515%0.15CC..THydrogen-bonded Turntrans-61.3-33-178.563.1-77.2000113.2H39 F41 W83 Y87 R323 M358H39-H319 AromaticContact CE1-CG 3.95Å; H39-H319 AromaticContact CE1-ND1 3.41Å; H39-H319 PolarHBondContact CE1-ND1 3.33Å; H39-H319 AromaticContact ND1-ND1 3.83Å; F41-H319 HydrophobicContact CD1-CB 3.92Å; F41-H319 HydrophobicContact CD2-CB 3.72Å; F41-H319 AromaticContact CD2-CG 3.97Å; F41-H319 HydrophobicContact CE1-CB 3.86Å; F41-H319 HydrophobicContact CE2-CB 3.64Å; F41-H319 AromaticContact CE2-CD2 3.6Å; F41-H319 AromaticContact CE2-CG 3.69Å; F41-H319 HydrophobicContact CG-CB 3.85Å; F41-H319 HydrophobicContact CZ-CB 3.72Å; F41-H319 AromaticContact CZ-CD2 3.9Å; W83-H319 AromaticContact CH2-CD2 3.95Å; W83-H319 AromaticContact CZ3-CD2 3.61Å; Y87-H319 AromaticContact CE1-NE2 3.84Å; Y87-H319 AromaticContact CZ-NE2 3.4Å; Y87-H319 PolarHBondContact OH-NE2 3.41Å; H319-R323 WeakPolarHBondContact O-CD 3.42Å; H319-R323 PolarHBondContact O-NH1 2.71Å; H319-M358 HydrophobicContact CB-CE 3.89Å
320D91.6Very high86.3Confident20 Ų2022.5 Ų22.511%0.10717%0.165CC..THydrogen-bonded Turntrans-73.2-55177.2-56.7-67.2000113W83 N318 Q322 R323 G324 S325W83-D320 WeakPolarHBondContact CH2-OD1 3.38Å; N318-D320 VanDerWaalsContact C-N 3.27Å; N318-D320 PolarHBondContact O-N 3.37Å; N318-D320 PolarHBondContact OD1-N 3.37Å; N318-D320 VanDerWaalsContact OD1-N 3.15Å; D320-Q322 VanDerWaalsContact C-N 3.3Å; D320-Q322 PolarHBondContact O-N 2.94Å; D320-R323 CarbonylContact O-C 3.57Å; D320-R323 WeakPolarHBondContact O-CA 3.37Å; D320-R323 WeakPolarHBondContact O-CB 3.41Å; D320-R323 PolarHBondContact O-N 3.49Å; D320-G324 PolarHBondContact O-N 2.94Å; D320-S325 CarbonylContact C-O 3.5Å; D320-S325 PolarHBondContact O-N 3.08Å
321N90.3Very high86.3Confident12 Ų1218.4 Ų18.46%0.06415%0.147CC..THydrogen-bonded Turntrans-76.2-18.9-17171.318.2000112.8D317 N318 R323 G324 S325 V331D317-N321 VanDerWaalsContact CA-OD1 3.29Å; D317-N321 WeakPolarHBondContact CA-OD1 3.45Å; D317-N321 WeakPolarHBondContact CB-OD1 3.49Å; N318-N321 PolarHBondContact N-OD1 2.58Å; N318-N321 PolarHBondContact O-OD1 3.48Å; N318-N321 WeakPolarHBondContact OD1-CB 3.32Å; N318-N321 PolarHBondContact OD1-N 2.65Å; N318-N321 PolarHBondContact OD1-ND2 2.87Å; N318-N321 PolarHBondContact OD1-OD1 3.28Å; N321-R323 PolarHBondContact O-N 2.82Å; N321-G324 PolarHBondContact O-N 3.4Å; N321-S325 WeakPolarHBondContact CA-O 3.49Å; N321-S325 PolarHBondContact N-O 3.37Å; N321-V331 HydrophobicContact CB-CG2 3.95Å
322Q90.5Very high86.2Confident2 Ų217.4 Ų17.41%0.00914%0.142CC..THydrogen-bonded Turntrans-59.5-34.1164.5-81.6-171.1-24.700111.5D317 N318 D320 T333 S360 F363 E417D317-Q322 HydrophobicContact CB-CG 4.05Å; D317-Q322 VanDerWaalsContact OD2-CG 3.22Å; D317-Q322 WeakPolarHBondContact OD2-CG 3.5Å; D317-Q322 PolarHBondContact OD2-NE2 3.2Å; N318-Q322 VanDerWaalsContact O-CB 3.3Å; N318-Q322 WeakPolarHBondContact O-CB 3.46Å; N318-Q322 WeakPolarHBondContact O-CG 3.31Å; N318-Q322 PolarHBondContact O-N 3.05Å; N318-Q322 VanDerWaalsContact O-N 3.1Å; D320-Q322 VanDerWaalsContact C-N 3.3Å; D320-Q322 PolarHBondContact O-N 2.94Å; Q322-T333 HydrophobicContact CB-CG2 4.3Å; Q322-T333 HydrophobicContact CG-CG2 3.88Å; Q322-S360 PolarHBondContact OE1-OG 3.17Å; Q322-F363 HydrophobicContact CB-CE1 4.47Å; Q322-F363 HydrophobicContact CB-CZ 4.1Å; Q322-F363 VanDerWaalsContact O-CZ 3.27Å; Q322-F363 WeakPolarHBondContact O-CZ 3.32Å; Q322-E417 PolarHBondContact NE2-OE1 3.47Å
323R87.5Confident86.1Confident4 Ų418 Ų182%0.01515%0.146CC..THydrogen-bonded Turntrans-92.5-27-177.8-64.8168.617861.611110.9H319 D320 N321 Y361 F363 H366 D367H319-R323 WeakPolarHBondContact O-CD 3.42Å; H319-R323 PolarHBondContact O-NH1 2.71Å; D320-R323 CarbonylContact O-C 3.57Å; D320-R323 WeakPolarHBondContact O-CA 3.37Å; D320-R323 WeakPolarHBondContact O-CB 3.41Å; D320-R323 PolarHBondContact O-N 3.49Å; N321-R323 PolarHBondContact O-N 2.82Å; R323-Y361 PolarHBondContact NE-OH 3.49Å; R323-Y361 PolarHBondContact NH2-OH 2.89Å; R323-F363 HydrophobicContact CB-CE2 4.41Å; R323-F363 HydrophobicContact CG-CD2 4.34Å; R323-F363 HydrophobicContact CG-CE1 4.04Å; R323-F363 HydrophobicContact CG-CE2 3.76Å; R323-F363 HydrophobicContact CG-CZ 3.61Å; R323-H366 CarbonylContact O-C 3.59Å; R323-D367 WeakPolarHBondContact CB-OD1 3.36Å; R323-D367 WeakPolarHBondContact CB-OD2 3.4Å; R323-D367 VanDerWaalsContact O-CB 3.23Å; R323-D367 WeakPolarHBondContact O-CB 3.29Å; R323-D367 PolarHBondContact O-N 3.45Å
324G78.5Confident85.9Confident34 Ų3418.8 Ų18.835%0.35115%0.149SC..THydrogen-bonded Turntrans118.54.9175.800000113.9D320 N321 D367D320-G324 PolarHBondContact O-N 2.94Å; N321-G324 PolarHBondContact O-N 3.4Å; G324-D367 PolarHBondContact N-OD2 2.65Å; G324-D367 VanDerWaalsContact N-OD2 3.14Å
325S73.2Confident85.7Confident44 Ų4422.5 Ų22.531%0.30817%0.165SC..  trans-99.1-179178-65.20000112.7D320 N321 G328 D367D320-S325 CarbonylContact C-O 3.5Å; D320-S325 PolarHBondContact O-N 3.08Å; N321-S325 WeakPolarHBondContact CA-O 3.49Å; N321-S325 PolarHBondContact N-O 3.37Å; S325-G328 WeakPolarHBondContact O-CA 3.34Å; S325-G328 PolarHBondContact O-N 3.44Å; S325-D367 VanDerWaalsContact CB-OD2 3.24Å; S325-D367 WeakPolarHBondContact CB-OD2 3.22Å; S325-D367 PolarHBondContact N-OD2 2.9Å; S325-D367 VanDerWaalsContact OG-CG 3.31Å; S325-D367 PolarHBondContact OG-OD2 3.22Å
326G63.5Low85.5Confident21 Ų2124.4 Ų24.422%0.21618%0.175CC..SBendtrans69.344.416800000115.2F278F278-G326 WeakPolarHBondContact CE1-O 3.3Å
327G60.7Low85.4Confident35 Ų3525.8 Ų25.836%0.36119%0.19SC..SBendtrans77.510.8-168.900000113Q259Q259-G327 PolarHBondContact NE2-O 3.42Å
328G56.6Low85.3Confident32 Ų3230.6 Ų30.633%0.3322%0.215SC..  trans-71165.7-171.100000116.9S325S325-G328 WeakPolarHBondContact O-CA 3.34Å; S325-G328 PolarHBondContact O-N 3.44Å
329G66.5Low85.4Confident38 Ų3834.9 Ų34.939%0.39223%0.231SC..SBendtrans125.4125-175.100000110.3L282 V331L282-G329 WeakPolarHBondContact CD2-O 3.5Å; G329-V331 PolarHBondContact O-N 3.5Å
330S83.4Confident85.6Confident98 Ų9834.9 Ų34.969%0.68523%0.231SC*.SBendtrans78.65.8172.1-37.20000118.4S285S285-S330 WeakPolarHBondContact CB-O 3.21Å
331V93.5Very high85.9Confident18 Ų1834.7 Ų34.711%0.10923%0.23CC..  trans-76.5150.3165.4-62.80000111.1L282 S285 D317 N321 G329 T333L282-V331 HydrophobicContact CD2-CG1 3.77Å; L282-V331 HydrophobicContact CG-CG1 4.22Å; S285-V331 WeakPolarHBondContact OG-CA 3.46Å; D317-V331 HydrophobicContact CB-CG2 4.43Å; N321-V331 HydrophobicContact CB-CG2 3.95Å; G329-V331 PolarHBondContact O-N 3.5Å; V331-T333 HydrophobicContact CG2-CG2 4.35Å
332L95.9Very high86.3Confident1 Ų134.3 Ų34.31%0.00523%0.227CC..  trans-76.6145.3167.7-69.3170.1000110.3S285 V288 V316 D336 R339 Y340 A343S285-L332 PolarHBondContact OG-N 3.23Å; V288-L332 HydrophobicContact CB-CD1 3.56Å; V288-L332 HydrophobicContact CG1-CD1 3.57Å; V288-L332 HydrophobicContact CG2-CD1 4.01Å; V316-L332 HydrophobicContact CG1-CB 4.24Å; L332-D336 WeakPolarHBondContact CA-OD2 3.42Å; L332-D336 HydrophobicContact CD2-CB 3.61Å; L332-D336 VanDerWaalsContact CD2-CG 3.48Å; L332-R339 HydrophobicContact CD1-CB 4.23Å; L332-R339 HydrophobicContact CD2-CB 4Å; L332-Y340 HydrophobicContact CB-CD2 4.35Å; L332-A343 HydrophobicContact CD1-CB 4.09Å
333T95.3Very high86.7Confident12 Ų1234.2 Ų34.27%0.07423%0.227CC..  trans-135.8178.3-179.669.50000110.1D317 Q322 V331 K335 D336 Y340D317-T333 HydrophobicContact CB-CG2 4.49Å; Q322-T333 HydrophobicContact CB-CG2 4.3Å; Q322-T333 HydrophobicContact CG-CG2 3.88Å; V331-T333 HydrophobicContact CG2-CG2 4.35Å; T333-K335 PolarHBondContact O-N 2.91Å; T333-K335 WeakPolarHBondContact OG1-CB 3.18Å; T333-K335 PolarHBondContact OG1-N 3.16Å; T333-D336 PolarHBondContact N-OD2 3.35Å; T333-D336 WeakPolarHBondContact O-CB 3.23Å; T333-D336 PolarHBondContact O-N 3.36Å; T333-D336 PolarHBondContact OG1-OD2 3.08Å; T333-Y340 VanDerWaalsContact C-CG 3.46Å; T333-Y340 WeakPolarHBondContact O-CB 3.24Å; T333-Y340 VanDerWaalsContact O-CG 3.31Å
334Y95.3Very high87.2Confident17 Ų1734 Ų347%0.06723%0.227CC..G310 helixtrans-51.6-25.9172.273.8-97.8000114.1D336 G337 Y361 Y362 F363 V415 E417Y334-D336 PolarHBondContact O-N 2.75Å; Y334-G337 PolarHBondContact O-N 3.1Å; Y334-Y361 PolarHBondContact OH-O 2.93Å; Y334-Y362 HydrophobicContact CD2-CE1 4.45Å; Y334-Y362 AromaticContact CE2-CD1 3.86Å; Y334-Y362 HydrophobicContact CE2-CD1 3.86Å; Y334-Y362 HydrophobicContact CE2-CE1 4.1Å; Y334-F363 AromaticContact CE1-CE1 3.82Å; Y334-F363 HydrophobicContact CE1-CE1 3.82Å; Y334-F363 HydrophobicContact CE1-CZ 4.38Å; Y334-F363 WeakPolarHBondContact OH-CD1 3.45Å; Y334-F363 WeakPolarHBondContact OH-CE1 3.27Å; Y334-F363 PolarHBondContact OH-N 2.94Å; Y334-V415 HydrophobicContact CD1-CG1 4.28Å; Y334-V415 HydrophobicContact CD1-CG2 4.19Å; Y334-V415 HydrophobicContact CD2-CG1 3.84Å; Y334-V415 HydrophobicContact CD2-CG2 3.83Å; Y334-V415 HydrophobicContact CE1-CG2 4.06Å; Y334-V415 HydrophobicContact CE2-CG2 3.71Å; Y334-V415 HydrophobicContact CG-CB 4.45Å; Y334-V415 HydrophobicContact CG-CG1 3.7Å; Y334-V415 HydrophobicContact CG-CG2 4.09Å; Y334-E417 WeakPolarHBondContact CD1-OE1 3.45Å
335K93.1Very high88.2Confident78 Ų7832.4 Ų32.434%0.33921%0.21SC..G310 helixtrans-66.4-14.6177.3-61-179.7172.9-178.70113.1T333 F363T333-K335 PolarHBondContact O-N 2.91Å; T333-K335 WeakPolarHBondContact OG1-CB 3.18Å; T333-K335 PolarHBondContact OG1-N 3.16Å; K335-F363 WeakPolarHBondContact CE-O 3.28Å; K335-F363 PolarHBondContact NZ-O 3.01Å
336D95.5Very high89.4Confident41 Ų4130.3 Ų30.322%0.21920%0.195CC..G310 helixtrans-96.7-1.7-178.8-60.8-78.3000114.3L332 T333 Y334 D338 R339L332-D336 WeakPolarHBondContact CA-OD2 3.42Å; L332-D336 HydrophobicContact CD2-CB 3.61Å; L332-D336 VanDerWaalsContact CD2-CG 3.48Å; T333-D336 PolarHBondContact N-OD2 3.35Å; T333-D336 WeakPolarHBondContact O-CB 3.23Å; T333-D336 PolarHBondContact O-N 3.36Å; T333-D336 PolarHBondContact OG1-OD2 3.08Å; Y334-D336 PolarHBondContact O-N 2.75Å; D336-D338 PolarHBondContact O-N 2.78Å; D336-R339 HydrophobicContact CB-CB 4.24Å; D336-R339 PolarHBondContact O-N 3.26Å; D336-R339 IonicContact OD1-CZ 2.63Å; D336-R339 IonicContact OD1-NH1 2.79Å; D336-R339 IonicContact OD1-NH2 2.66Å; D336-R339 PolarHBondContact OD1-NH2 3.39Å
337G95.2Very high91.1Very high30 Ų3029.4 Ų29.431%0.30919%0.185SC..THydrogen-bonded Turntrans57.7-126.2173.700000113.8Y334 R339 Y340 F341Y334-G337 PolarHBondContact O-N 3.1Å; G337-R339 PolarHBondContact O-N 3.28Å; G337-R339 VanDerWaalsContact O-N 3.08Å; G337-Y340 WeakPolarHBondContact O-CB 3.27Å; G337-Y340 PolarHBondContact O-N 3.42Å; G337-F341 PolarHBondContact O-N 2.96Å
338D95.2Very high92.9Very high102 Ų10227.7 Ų27.755%0.54517%0.168SC..Hα-helixtrans-53.3-30.6-178.9-85.814.3000113.4D336 M342 K515D336-D338 PolarHBondContact O-N 2.78Å; D338-M342 PolarHBondContact O-N 2.89Å; D338-K515 IonicContact OD2-NZ 2.73Å; D338-K515 PolarHBondContact OD2-NZ 3.09Å
339R97.7Very high94.9Very high92 Ų9226.2 Ų26.235%0.34715%0.152SC..Hα-helixtrans-67.3-45.1176.6-73-174.8-66.8145.84.2111.4V288 N289 L332 D336 G337 M342 A343V288-R339 HydrophobicContact CG1-CB 3.73Å; V288-R339 HydrophobicContact CG1-CG 3.97Å; N289-R339 PolarHBondContact OD1-NH1 2.99Å; L332-R339 HydrophobicContact CD1-CB 4.23Å; L332-R339 HydrophobicContact CD2-CB 4Å; D336-R339 HydrophobicContact CB-CB 4.24Å; D336-R339 PolarHBondContact O-N 3.26Å; D336-R339 IonicContact OD1-CZ 2.63Å; D336-R339 IonicContact OD1-NH1 2.79Å; D336-R339 IonicContact OD1-NH2 2.66Å; D336-R339 PolarHBondContact OD1-NH2 3.39Å; G337-R339 PolarHBondContact O-N 3.28Å; G337-R339 VanDerWaalsContact O-N 3.08Å; R339-M342 WeakPolarHBondContact O-CB 3.18Å; R339-M342 PolarHBondContact O-N 2.95Å; R339-A343 PolarHBondContact O-N 2.93Å
340Y98.2Very high96.4Very high1 Ų125 Ų250%0.00414%0.136CC..Hα-helixtrans-63.6-43.3175.3169-106.4000111.4V316 D317 L332 T333 G337 M342 A343 V344 E417 W420 I423V316-Y340 HydrophobicContact CB-CE2 4.1Å; V316-Y340 HydrophobicContact CG1-CD2 3.91Å; V316-Y340 HydrophobicContact CG1-CE2 3.95Å; D317-Y340 WeakPolarHBondContact OD1-CE2 3.44Å; D317-Y340 PolarHBondContact OD1-OH 2.55Å; L332-Y340 HydrophobicContact CB-CD2 4.35Å; T333-Y340 VanDerWaalsContact C-CG 3.46Å; T333-Y340 WeakPolarHBondContact O-CB 3.24Å; T333-Y340 VanDerWaalsContact O-CG 3.31Å; G337-Y340 WeakPolarHBondContact O-CB 3.27Å; G337-Y340 PolarHBondContact O-N 3.42Å; Y340-M342 VanDerWaalsContact C-N 3.28Å; Y340-M342 PolarHBondContact O-N 2.86Å; Y340-A343 WeakPolarHBondContact O-CB 3.22Å; Y340-A343 PolarHBondContact O-N 2.74Å; Y340-A343 VanDerWaalsContact O-N 3.14Å; Y340-V344 HydrophobicContact CD1-CG2 4.32Å; Y340-V344 HydrophobicContact CD2-CG2 4.12Å; Y340-V344 HydrophobicContact CE1-CG2 3.85Å; Y340-V344 HydrophobicContact CE2-CG2 3.61Å; Y340-V344 HydrophobicContact CG-CG2 4.45Å; Y340-V344 VanDerWaalsContact CZ-CG2 3.47Å; Y340-V344 WeakPolarHBondContact O-CG2 3.3Å; Y340-V344 PolarHBondContact O-N 3.14Å; Y340-E417 HydrophobicContact CE1-CB 4.12Å; Y340-E417 HydrophobicContact CE1-CG 3.94Å; Y340-W420 HydrophobicContact CD1-CH2 4.24Å; Y340-W420 AromaticContact CD1-CZ3 3.83Å; Y340-W420 HydrophobicContact CD1-CZ3 3.83Å; Y340-W420 HydrophobicContact CE1-CZ3 4.32Å; Y340-I423 HydrophobicContact CE1-CD1 3.98Å
341F98.1Very high97.1Very high16 Ų1622.8 Ų22.87%0.0712%0.119CC..Hα-helixtrans-55.6-43.5172.8166.3-110.9000111.9G337 A343 V344 A345 T422 I423 M426 V485 V516G337-F341 PolarHBondContact O-N 2.96Å; F341-A343 VanDerWaalsContact C-N 3.32Å; F341-A343 PolarHBondContact O-N 2.72Å; F341-V344 PolarHBondContact O-N 3.44Å; F341-A345 HydrophobicContact CD2-CB 4.37Å; F341-A345 HydrophobicContact CE1-CB 4.39Å; F341-A345 HydrophobicContact CE2-CB 3.76Å; F341-A345 HydrophobicContact CZ-CB 3.77Å; F341-A345 VanDerWaalsContact O-CB 3.25Å; F341-A345 WeakPolarHBondContact O-CB 3.44Å; F341-A345 PolarHBondContact O-N 3.39Å; F341-T422 VanDerWaalsContact CD2-OG1 3.24Å; F341-T422 WeakPolarHBondContact CD2-OG1 3.38Å; F341-T422 HydrophobicContact CE1-CG2 4.46Å; F341-T422 HydrophobicContact CE2-CG2 4.42Å; F341-T422 HydrophobicContact CZ-CG2 4.31Å; F341-I423 HydrophobicContact CD2-CG1 4Å; F341-M426 HydrophobicContact CE2-CG 3.91Å; F341-M426 HydrophobicContact CZ-CG 4.23Å; F341-V485 HydrophobicContact CE1-CG1 3.72Å; F341-V485 HydrophobicContact CZ-CG1 3.65Å; F341-V485 HydrophobicContact CZ-CG2 4.17Å; F341-V516 HydrophobicContact CE1-CB 4.27Å
342M98.5Very high97.3Very high4 Ų422.4 Ų22.42%0.0212%0.116CC..Hα-helixtrans-58.9-42.7178.1-177.6-177.7-65.400112.4V288 F294 D338 R339 Y340 F346 L460 N462 R514 V516V288-M342 HydrophobicContact CG1-SD 4.28Å; V288-M342 HydrophobicContact CG2-CB 4.42Å; V288-M342 HydrophobicContact CG2-CG 4.18Å; V288-M342 HydrophobicContact CG2-SD 4.11Å; F294-M342 HydrophobicContact CE2-SD 4.42Å; D338-M342 PolarHBondContact O-N 2.89Å; R339-M342 WeakPolarHBondContact O-CB 3.18Å; R339-M342 PolarHBondContact O-N 2.95Å; Y340-M342 VanDerWaalsContact C-N 3.28Å; Y340-M342 PolarHBondContact O-N 2.86Å; M342-F346 PolarHBondContact O-N 3.37Å; M342-L460 HydrophobicContact CG-CD1 3.48Å; M342-L460 VanDerWaalsContact CG-CD1 3.48Å; M342-L460 HydrophobicContact CG-CD2 4.49Å; M342-L460 HydrophobicContact CG-CG 3.9Å; M342-L460 HydrophobicContact SD-CD1 4.06Å; M342-L460 HydrophobicContact SD-CD2 4.01Å; M342-L460 HydrophobicContact SD-CG 4Å; M342-N462 HydrophobicContact CE-CB 4.37Å; M342-N462 HydrophobicContact SD-CB 3.77Å; M342-N462 PolarHBondContact SD-OD1 3.39Å; M342-R514 HydrophobicContact CE-CB 4.26Å; M342-V516 HydrophobicContact CB-CG2 4.32Å; M342-V516 HydrophobicContact CG-CG2 3.9Å
343A98.7Very high97.4Very high0 Ų022.8 Ų22.80%012%0.12CC..Hα-helixtrans-62.8-50174.500000111.2L284 V288 V316 L332 R339 Y340 F341 A345 F346 M347L284-A343 HydrophobicContact CD2-CB 4.15Å; L284-A343 VanDerWaalsContact CD2-O 3.29Å; L284-A343 WeakPolarHBondContact CD2-O 3.38Å; L284-A343 HydrophobicContact CG-CB 3.9Å; V288-A343 HydrophobicContact CG2-CB 4.18Å; V316-A343 HydrophobicContact CG1-CB 3.8Å; V316-A343 HydrophobicContact CG2-CB 3.81Å; L332-A343 HydrophobicContact CD1-CB 4.09Å; R339-A343 PolarHBondContact O-N 2.93Å; Y340-A343 WeakPolarHBondContact O-CB 3.22Å; Y340-A343 PolarHBondContact O-N 2.74Å; Y340-A343 VanDerWaalsContact O-N 3.14Å; F341-A343 VanDerWaalsContact C-N 3.32Å; F341-A343 PolarHBondContact O-N 2.72Å; A343-A345 VanDerWaalsContact C-N 3.32Å; A343-A345 PolarHBondContact O-N 2.94Å; A343-F346 PolarHBondContact O-N 3.1Å; A343-M347 PolarHBondContact O-N 2.78Å
344V98.8Very high97.5Very high1 Ų122.8 Ų22.81%0.00612%0.119CC..Hα-helixtrans-60.8-41178.8174.50000111.6V316 Y340 F341 M347 L348 I357 I423V316-V344 HydrophobicContact CB-CG2 4.44Å; V316-V344 HydrophobicContact CG2-CG2 3.89Å; Y340-V344 HydrophobicContact CD1-CG2 4.32Å; Y340-V344 HydrophobicContact CD2-CG2 4.12Å; Y340-V344 HydrophobicContact CE1-CG2 3.85Å; Y340-V344 HydrophobicContact CE2-CG2 3.61Å; Y340-V344 HydrophobicContact CG-CG2 4.45Å; Y340-V344 VanDerWaalsContact CZ-CG2 3.47Å; Y340-V344 WeakPolarHBondContact O-CG2 3.3Å; Y340-V344 PolarHBondContact O-N 3.14Å; F341-V344 PolarHBondContact O-N 3.44Å; V344-M347 HydrophobicContact CG1-CE 4.48Å; V344-M347 PolarHBondContact O-N 3.16Å; V344-L348 HydrophobicContact CG1-CD1 3.8Å; V344-L348 HydrophobicContact CG1-CG 4.3Å; V344-L348 WeakPolarHBondContact O-CB 3.4Å; V344-L348 WeakPolarHBondContact O-CG 3.29Å; V344-L348 PolarHBondContact O-N 2.9Å; V344-I357 HydrophobicContact CG1-CG2 3.96Å; V344-I423 HydrophobicContact CB-CD1 4.47Å; V344-I423 HydrophobicContact CG1-CD1 4.14Å; V344-I423 HydrophobicContact CG1-CG1 3.99Å; V344-I423 HydrophobicContact CG1-CG2 4.2Å; V344-I423 HydrophobicContact CG2-CD1 4.47Å
345A98.8Very high97.7Very high0 Ų022 Ų220%012%0.117CC..Hα-helixtrans-63.7-43.5178.400000111.8F341 A343 L348 A349 M426 F458 V516F341-A345 HydrophobicContact CD2-CB 4.37Å; F341-A345 HydrophobicContact CE1-CB 4.39Å; F341-A345 HydrophobicContact CE2-CB 3.76Å; F341-A345 HydrophobicContact CZ-CB 3.77Å; F341-A345 VanDerWaalsContact O-CB 3.25Å; F341-A345 WeakPolarHBondContact O-CB 3.44Å; F341-A345 PolarHBondContact O-N 3.39Å; A343-A345 VanDerWaalsContact C-N 3.32Å; A343-A345 PolarHBondContact O-N 2.94Å; A345-L348 PolarHBondContact O-N 3.3Å; A345-A349 VanDerWaalsContact O-CB 3.31Å; A345-A349 WeakPolarHBondContact O-CB 3.35Å; A345-A349 PolarHBondContact O-N 2.7Å; A345-M426 HydrophobicContact CB-CE 4.3Å; A345-M426 HydrophobicContact CB-CG 3.97Å; A345-M426 HydrophobicContact CB-SD 4.4Å; A345-M426 WeakPolarHBondContact O-CE 3.4Å; A345-F458 HydrophobicContact CB-CE2 4.17Å; A345-F458 HydrophobicContact CB-CZ 4.44Å; A345-V516 HydrophobicContact CB-CG1 4.05Å
346F98.9Very high98Very high0 Ų018.4 Ų18.40%010%0.101CC..Hα-helixtrans-61.8-45.7173.9-176.5-87.8000111.2L284 F294 Y297 F300 M342 A343 L348 A349 W350 I448 F450 F458 L460L284-F346 HydrophobicContact CD1-CB 4.14Å; L284-F346 HydrophobicContact CD1-CD1 3.56Å; L284-F346 HydrophobicContact CD1-CE1 4.27Å; L284-F346 HydrophobicContact CD1-CG 3.98Å; L284-F346 HydrophobicContact CD2-CD1 4.14Å; F294-F346 HydrophobicContact CD1-CD2 4.44Å; F294-F346 HydrophobicContact CD1-CE2 4.41Å; F294-F346 HydrophobicContact CE1-CD2 4.02Å; F294-F346 HydrophobicContact CE1-CE2 4.35Å; F294-F346 HydrophobicContact CE1-CG 4.25Å; Y297-F346 HydrophobicContact CD1-CE1 4.1Å; Y297-F346 HydrophobicContact CD1-CZ 4.04Å; F300-F346 AromaticContact CD1-CE1 3.67Å; F300-F346 HydrophobicContact CD1-CE1 3.67Å; F300-F346 HydrophobicContact CD1-CZ 4.48Å; F300-F346 HydrophobicContact CE1-CE1 4.19Å; F300-F346 HydrophobicContact CG-CE1 4.35Å; M342-F346 PolarHBondContact O-N 3.37Å; A343-F346 PolarHBondContact O-N 3.1Å; F346-L348 VanDerWaalsContact C-N 3.31Å; F346-L348 PolarHBondContact O-N 3.06Å; F346-A349 PolarHBondContact O-N 3.2Å; F346-A349 VanDerWaalsContact O-N 3.16Å; F346-W350 HydrophobicContact CD1-CB 4.31Å; F346-W350 HydrophobicContact CE1-CB 3.95Å; F346-W350 HydrophobicContact CE1-CD2 4.35Å; F346-W350 AromaticContact CE1-CG 3.99Å; F346-W350 HydrophobicContact CE1-CG 3.99Å; F346-W350 HydrophobicContact CE2-CE3 4.45Å; F346-W350 HydrophobicContact CZ-CB 4.27Å; F346-W350 HydrophobicContact CZ-CD2 4.01Å; F346-W350 HydrophobicContact CZ-CE3 4.01Å; F346-W350 HydrophobicContact CZ-CG 4.12Å; F346-W350 VanDerWaalsContact O-CB 3.26Å; F346-W350 WeakPolarHBondContact O-CB 3.44Å; F346-W350 PolarHBondContact O-N 3.11Å; F346-I448 HydrophobicContact CD2-CG2 4.33Å; F346-I448 HydrophobicContact CE2-CD1 4.29Å; F346-I448 HydrophobicContact CE2-CG2 3.98Å; F346-F450 HydrophobicContact CE2-CE1 4.21Å; F346-F458 HydrophobicContact CB-CZ 4.38Å; F346-F458 HydrophobicContact CD2-CE1 4.07Å; F346-L460 HydrophobicContact CB-CD1 4.1Å; F346-L460 HydrophobicContact CD2-CD1 4.16Å
347M98.8Very high98.1Very high1 Ų116.6 Ų16.61%0.0059%0.091CC..Hα-helixtrans-58.5-40.7177.8178.8-179.570.500112.7Y280 L284 V314 F315 V316 A343 V344 P355 I357Y280-M347 HydrophobicContact CE1-CB 4.03Å; Y280-M347 HydrophobicContact CE1-CG 3.72Å; Y280-M347 HydrophobicContact CE1-SD 4.02Å; Y280-M347 WeakPolarHBondContact OH-CA 3.49Å; L284-M347 HydrophobicContact CD2-CB 4.12Å; V314-M347 HydrophobicContact CG2-CG 4.2Å; V314-M347 HydrophobicContact CG2-SD 4.27Å; F315-M347 VanDerWaalsContact CA-SD 3.54Å; V316-M347 HydrophobicContact CG2-CE 4.26Å; V316-M347 HydrophobicContact CG2-SD 4.17Å; A343-M347 PolarHBondContact O-N 2.78Å; V344-M347 HydrophobicContact CG1-CE 4.48Å; V344-M347 PolarHBondContact O-N 3.16Å; M347-P355 HydrophobicContact CE-CB 4.03Å; M347-P355 HydrophobicContact CG-CB 3.85Å; M347-P355 HydrophobicContact SD-CB 4.04Å; M347-I357 HydrophobicContact CE-CG2 3.82Å
348L98.8Very high98.3Very high0 Ų015.1 Ų15.10%08%0.076CC..Hα-helixtrans-75.3-27.2178.7-68.9173.8000112.9V36 V344 A345 F346 P355 M426 T427 R430V36-L348 HydrophobicContact CG1-CD2 4.03Å; V36-L348 HydrophobicContact CG2-CD2 3.75Å; V344-L348 HydrophobicContact CG1-CD1 3.8Å; V344-L348 HydrophobicContact CG1-CG 4.3Å; V344-L348 WeakPolarHBondContact O-CB 3.4Å; V344-L348 WeakPolarHBondContact O-CG 3.29Å; V344-L348 PolarHBondContact O-N 2.9Å; A345-L348 PolarHBondContact O-N 3.3Å; F346-L348 VanDerWaalsContact C-N 3.31Å; F346-L348 PolarHBondContact O-N 3.06Å; L348-P355 HydrophobicContact CD2-CB 4.19Å; L348-P355 HydrophobicContact CD2-CG 4.04Å; L348-M426 HydrophobicContact CB-CB 4.23Å; L348-M426 HydrophobicContact CB-CE 4.48Å; L348-M426 HydrophobicContact CD1-CB 3.57Å; L348-T427 HydrophobicContact CD1-CG2 4.19Å; L348-R430 HydrophobicContact CB-CB 4.36Å; L348-R430 HydrophobicContact CD2-CG 4.4Å; L348-R430 WeakPolarHBondContact O-CB 3.42Å; L348-R430 WeakPolarHBondContact O-CG 3.36Å
349A98.7Very high98.4Very high0 Ų010.3 Ų10.30%05%0.05CC..Hα-helixtrans-84.6-25.7178.400000113.8A345 F346 M426 F429 F450 R452 F458A345-A349 VanDerWaalsContact O-CB 3.31Å; A345-A349 WeakPolarHBondContact O-CB 3.35Å; A345-A349 PolarHBondContact O-N 2.7Å; F346-A349 PolarHBondContact O-N 3.2Å; F346-A349 VanDerWaalsContact O-N 3.16Å; A349-M426 HydrophobicContact CB-CE 4.09Å; A349-F429 HydrophobicContact CB-CD1 4.31Å; A349-F429 HydrophobicContact CB-CE1 3.78Å; A349-F450 HydrophobicContact CB-CE2 4.33Å; A349-F450 HydrophobicContact CB-CZ 3.97Å; A349-F450 WeakPolarHBondContact O-CE2 3.44Å; A349-R452 WeakPolarHBondContact O-CD 3.22Å; A349-R452 PolarHBondContact O-NH1 3.28Å; A349-F458 HydrophobicContact CB-CB 3.97Å; A349-F458 HydrophobicContact CB-CD1 4Å; A349-F458 HydrophobicContact CB-CD2 3.29Å; A349-F458 HydrophobicContact CB-CE1 4.3Å; A349-F458 HydrophobicContact CB-CE2 3.63Å; A349-F458 HydrophobicContact CB-CG 3.48Å; A349-F458 VanDerWaalsContact CB-CG 3.48Å; A349-F458 HydrophobicContact CB-CZ 4.12Å
350W98.5Very high98.4Very high14 Ų145.9 Ų5.95%0.0533%0.034CC..SBendtrans-90.3129.8-175.4-168.6-102.5000112G298 F300 F346 Y352 V438 M441 F450G298-W350 WeakPolarHBondContact O-CH2 3.06Å; F300-W350 HydrophobicContact CB-CZ2 4.41Å; F300-W350 PolarHBondContact O-NE1 3.06Å; F346-W350 HydrophobicContact CD1-CB 4.31Å; F346-W350 HydrophobicContact CE1-CB 3.95Å; F346-W350 HydrophobicContact CE1-CD2 4.35Å; F346-W350 AromaticContact CE1-CG 3.99Å; F346-W350 HydrophobicContact CE1-CG 3.99Å; F346-W350 HydrophobicContact CE2-CE3 4.45Å; F346-W350 HydrophobicContact CZ-CB 4.27Å; F346-W350 HydrophobicContact CZ-CD2 4.01Å; F346-W350 HydrophobicContact CZ-CE3 4.01Å; F346-W350 HydrophobicContact CZ-CG 4.12Å; F346-W350 VanDerWaalsContact O-CB 3.26Å; F346-W350 WeakPolarHBondContact O-CB 3.44Å; F346-W350 PolarHBondContact O-N 3.11Å; W350-Y352 PolarHBondContact O-N 2.96Å; W350-V438 HydrophobicContact CE3-CG2 4.1Å; W350-V438 HydrophobicContact CH2-CG1 4.27Å; W350-V438 HydrophobicContact CH2-CG2 4.02Å; W350-V438 HydrophobicContact CZ3-CG1 4.01Å; W350-V438 HydrophobicContact CZ3-CG2 3.75Å; W350-M441 HydrophobicContact CH2-SD 4.41Å; W350-F450 HydrophobicContact CE3-CD1 4.23Å; W350-F450 AromaticContact CE3-CE1 3.72Å; W350-F450 HydrophobicContact CE3-CE1 3.72Å; W350-F450 HydrophobicContact CE3-CE2 4.23Å; W350-F450 AromaticContact CE3-CZ 3.72Å; W350-F450 HydrophobicContact CE3-CZ 3.72Å; W350-F450 HydrophobicContact CZ3-CD1 4.06Å; W350-F450 HydrophobicContact CZ3-CE1 4.01Å; W350-F450 HydrophobicContact CZ3-CG 4.44Å; W350-F450 HydrophobicContact CZ3-CZ 4.34Å
351P97.3Very high98.3Very high50 Ų505.9 Ų5.933%0.3253%0.034SC..  trans-82.976.7-178.831-30000111.7V438P351-V438 HydrophobicContact CG-CG2 3.56Å
352Y97.8Very high98.1Very high10 Ų109 Ų94%0.0395%0.046CC..SBendtrans-145.3122.6171.7-179.7-102.6000111.2Y280 E302 Y306 W307 D309 V312 V314 W350Y280-Y352 AromaticContact CD2-CD1 3.82Å; Y280-Y352 HydrophobicContact CD2-CD1 3.82Å; Y280-Y352 HydrophobicContact CD2-CE1 4Å; Y280-Y352 AromaticContact CE2-CD1 3.68Å; Y280-Y352 HydrophobicContact CE2-CD1 3.68Å; Y280-Y352 HydrophobicContact CE2-CE1 4.33Å; E302-Y352 HydrophobicContact CG-CE2 4.26Å; Y306-Y352 WeakPolarHBondContact CB-OH 3.39Å; Y306-Y352 AromaticContact CD2-CE1 3.86Å; Y306-Y352 HydrophobicContact CD2-CE1 3.86Å; W307-Y352 PolarHBondContact O-OH 2.93Å; D309-Y352 HydrophobicContact CB-CD2 4.22Å; D309-Y352 HydrophobicContact CB-CE2 4.43Å; D309-Y352 WeakPolarHBondContact OD1-CA 2.74Å; V312-Y352 HydrophobicContact CG2-CD1 4.42Å; V312-Y352 HydrophobicContact CG2-CE1 3.73Å; V312-Y352 HydrophobicContact CG2-CE2 4.17Å; V314-Y352 HydrophobicContact CG1-CD1 3.85Å; V314-Y352 HydrophobicContact CG1-CE1 3.79Å; V314-Y352 WeakPolarHBondContact CG2-O 3.29Å; W350-Y352 PolarHBondContact O-N 2.96Å
353G97.7Very high97.7Very high10 Ų109.3 Ų9.310%0.1035%0.047CC..SBendtrans66.4-178.317900000114.8D309 V312 P355D309-G353 PolarHBondContact OD1-N 2.82Å; V312-G353 WeakPolarHBondContact O-CA 3.02Å; G353-P355 WeakPolarHBondContact O-CD 3.4Å
354I98.3Very high96.8Very high11 Ų1116 Ų166%0.0568%0.082CC..EExtended strand (participates in β ladder)trans-87.2115168.4-66.1170.2000108.2L28 V37 F251 R274 V312 L313 V314L28-I354 HydrophobicContact CB-CD1 3.98Å; L28-I354 HydrophobicContact CD1-CD1 4.34Å; L28-I354 HydrophobicContact CD2-CD1 4.11Å; L28-I354 HydrophobicContact CD2-CG1 4.42Å; L28-I354 HydrophobicContact CD2-CG2 3.82Å; L28-I354 HydrophobicContact CG-CD1 4.38Å; V37-I354 HydrophobicContact CG2-CG2 3.58Å; F251-I354 HydrophobicContact CE2-CD1 3.7Å; F251-I354 HydrophobicContact CZ-CD1 3.76Å; R274-I354 VanDerWaalsContact NE-CD1 3.33Å; V312-I354 PolarHBondContact O-N 3.36Å; V312-I354 VanDerWaalsContact O-N 3.1Å; L313-I354 CarbonylContact C-O 3.45Å; L313-I354 WeakPolarHBondContact CA-O 3.39Å; L313-I354 HydrophobicContact CD1-CG2 4.46Å; L313-I354 HydrophobicContact CG-CB 4.45Å; L313-I354 HydrophobicContact CG-CG2 4.43Å; L313-I354 WeakPolarHBondContact CG-O 3.21Å; V314-I354 PolarHBondContact N-O 2.9Å
355P98.7Very high95.2Very high1 Ų119.4 Ų19.41%0.00610%0.101CC..EExtended strand (participates in β ladder)trans-78.5132.7176.733.8-35.2000110.7V36 V37 V314 M347 L348 G353 R430V36-P355 HydrophobicContact CG2-CG 4.27Å; V37-P355 PolarHBondContact N-O 3.45Å; V314-P355 HydrophobicContact CG2-CB 4.29Å; V314-P355 CarbonylContact O-C 3.49Å; V314-P355 WeakPolarHBondContact O-CA 3.35Å; M347-P355 HydrophobicContact CE-CB 4.03Å; M347-P355 HydrophobicContact CG-CB 3.85Å; M347-P355 HydrophobicContact SD-CB 4.04Å; L348-P355 HydrophobicContact CD2-CB 4.19Å; L348-P355 HydrophobicContact CD2-CG 4.04Å; G353-P355 WeakPolarHBondContact O-CD 3.4Å; P355-R430 VanDerWaalsContact CD-CZ 3.44Å; P355-R430 VanDerWaalsContact CD-NH1 3.29Å
356R98.8Very high93.1Very high3 Ų324.7 Ų24.71%0.01113%0.125CC..EExtended strand (participates in β ladder)trans-112.5128168.2-172.6-17269.4-164.9-9.1109.9V37 H39 L313 V314 F315 N318V37-R356 HydrophobicContact CB-CB 4.17Å; V37-R356 HydrophobicContact CB-CG 4.05Å; V37-R356 HydrophobicContact CG1-CG 4.02Å; V37-R356 CarbonylContact O-C 3.56Å; V37-R356 VanDerWaalsContact O-CA 3.22Å; V37-R356 WeakPolarHBondContact O-CA 3.37Å; H39-R356 HydrophobicContact CB-CG 4.37Å; L313-R356 HydrophobicContact CD1-CB 4.48Å; L313-R356 HydrophobicContact CD2-CB 3.73Å; L313-R356 HydrophobicContact CG-CB 4.32Å; V314-R356 PolarHBondContact O-N 3.3Å; F315-R356 WeakPolarHBondContact CB-O 3.28Å; F315-R356 VanDerWaalsContact CD1-NH2 3.28Å; N318-R356 VanDerWaalsContact CB-NH2 3.31Å
357I98.8Very high90.9Very high2 Ų225.5 Ų25.51%0.0113%0.13CC..EExtended strand (participates in β ladder)trans-101.2147.9171.761175.2000110.2V36 V37 V38 H39 I61 V344 M347 H418 I423 T427V36-I357 HydrophobicContact CG1-CD1 4.41Å; V36-I357 HydrophobicContact CG1-CG1 4.35Å; V37-I357 PolarHBondContact O-N 3.33Å; V38-I357 WeakPolarHBondContact CA-O 3.14Å; V38-I357 HydrophobicContact CB-CD1 4.46Å; V38-I357 HydrophobicContact CB-CG1 4.02Å; V38-I357 HydrophobicContact CG2-CD1 4.46Å; V38-I357 HydrophobicContact CG2-CG1 4.07Å; H39-I357 PolarHBondContact N-O 3.39Å; I61-I357 HydrophobicContact CD1-CD1 4.02Å; V344-I357 HydrophobicContact CG1-CG2 3.96Å; M347-I357 HydrophobicContact CE-CG2 3.82Å; I357-H418 HydrophobicContact CD1-CB 3.62Å; I357-H418 HydrophobicContact CG1-CB 4.38Å; I357-I423 HydrophobicContact CD1-CG2 3.95Å; I357-T427 HydrophobicContact CD1-CG2 4.36Å
358M98.4Very high88.1Confident0 Ų031.5 Ų31.50%016%0.158CC..EExtended strand (participates in β ladder)trans-82151174.8-82.2-62.7-6400111.9H39 F41 H319 E417H39-M358 HydrophobicContact CB-SD 3.87Å; F41-M358 HydrophobicContact CB-CE 4.01Å; F41-M358 HydrophobicContact CG-CE 4.45Å; H319-M358 HydrophobicContact CB-CE 3.89Å; M358-E417 WeakPolarHBondContact O-CB 3.27Å
359S98.7Very high85.2Confident0 Ų034.7 Ų34.70%018%0.184CC..EExtended strand (participates in β ladder)trans-129.1105.3157.5176.30000107.1H39 F41 W43 E417 H418H39-S359 WeakPolarHBondContact O-CB 3.25Å; H39-S359 PolarHBondContact O-N 3.1Å; F41-S359 PolarHBondContact N-O 3.23Å; W43-S359 WeakPolarHBondContact CZ2-OG 3.23Å; W43-S359 PolarHBondContact NE1-OG 3.27Å; S359-E417 WeakPolarHBondContact CA-OE2 3.34Å; S359-H418 VanDerWaalsContact CB-ND1 3.28Å; S359-H418 WeakPolarHBondContact CB-ND1 3.34Å; S359-H418 PolarHBondContact OG-CE1 3.01Å; S359-H418 PolarHBondContact OG-ND1 3.03Å; S359-H418 VanDerWaalsContact OG-ND1 3.12Å
360S96.8Very high82.1Confident0 Ų042.5 Ų42.50%022%0.218CC..  trans-110.6-176.3-170.6-154.90000111.8Q322 V415 E417Q322-S360 PolarHBondContact OE1-OG 3.17Å; S360-V415 WeakPolarHBondContact O-CB 3.35Å; S360-V415 PolarHBondContact O-N 2.87Å; S360-E417 WeakPolarHBondContact CB-OE1 3.48Å; S360-E417 PolarHBondContact N-OE2 3.22Å
361Y96.7Very high78.9Confident1 Ų147.5 Ų47.50%0.00425%0.25CS..BIsolated β-bridgetrans-124.4159.4171.159.4-97.4000110.4F41 E42 W83 R323 Y334 F363 Q385 G386 P387 G413 W414F41-Y361 HydrophobicContact CD1-CD1 4.36Å; F41-Y361 AromaticContact CD1-CE1 3.83Å; F41-Y361 HydrophobicContact CD1-CE1 3.83Å; F41-Y361 AromaticContact CE1-CE1 3.7Å; F41-Y361 HydrophobicContact CE1-CE1 3.7Å; E42-Y361 HydrophobicContact CB-CE1 4.26Å; E42-Y361 HydrophobicContact CG-CE1 3.96Å; W83-Y361 VanDerWaalsContact CB-OH 3.23Å; W83-Y361 WeakPolarHBondContact CB-OH 3.33Å; R323-Y361 PolarHBondContact NE-OH 3.49Å; R323-Y361 PolarHBondContact NH2-OH 2.89Å; Y334-Y361 PolarHBondContact OH-O 2.93Å; Y361-F363 HydrophobicContact CD2-CD1 4.44Å; Y361-F363 HydrophobicContact CE2-CB 4.24Å; Y361-F363 HydrophobicContact CE2-CD1 4.29Å; Y361-F363 VanDerWaalsContact O-CD1 3.23Å; Y361-F363 WeakPolarHBondContact O-CD1 3.25Å; Y361-F363 PolarHBondContact O-N 2.79Å; Y361-Q385 PolarHBondContact OH-O 3.03Å; Y361-Q385 VanDerWaalsContact OH-O 3.1Å; Y361-G386 VanDerWaalsContact CE2-O 3.23Å; Y361-G386 WeakPolarHBondContact CE2-O 3.43Å; Y361-P387 HydrophobicContact CD1-CB 4.1Å; Y361-P387 HydrophobicContact CE1-CB 4.04Å; Y361-G413 WeakPolarHBondContact CA-O 3.38Å; Y361-G413 WeakPolarHBondContact CB-O 3.23Å; Y361-W414 HydrophobicContact CD1-CZ3 4.13Å
362Y93.6Very high75.8Confident81 Ų8154.3 Ų54.332%0.31828%0.278SS..  trans-70.4131.1179.7-69.7-73.6000110.4Y334 Q410 G413 W414 V415Y334-Y362 HydrophobicContact CD2-CE1 4.45Å; Y334-Y362 AromaticContact CE2-CD1 3.86Å; Y334-Y362 HydrophobicContact CE2-CD1 3.86Å; Y334-Y362 HydrophobicContact CE2-CE1 4.1Å; Y362-Q410 HydrophobicContact CD2-CG 4.38Å; Y362-Q410 HydrophobicContact CE2-CB 4.39Å; Y362-Q410 HydrophobicContact CE2-CG 3.9Å; Y362-G413 WeakPolarHBondContact CD2-O 3.37Å; Y362-G413 PolarHBondContact N-O 2.81Å; Y362-W414 VanDerWaalsContact CE2-O 3.24Å; Y362-W414 WeakPolarHBondContact CE2-O 3.46Å; Y362-V415 HydrophobicContact CD1-CG2 3.77Å; Y362-V415 HydrophobicContact CD2-CG2 4.02Å; Y362-V415 HydrophobicContact CE1-CG2 3.78Å; Y362-V415 HydrophobicContact CE2-CG2 4.01Å; Y362-V415 HydrophobicContact CG-CG2 3.89Å
363F89.7Confident72.7Confident10 Ų1061.5 Ų61.54%0.04431%0.309CS..  trans-142.9141.8172.560.5-91000112.3Q322 R323 Y334 K335 Y361 N365 Q385Q322-F363 HydrophobicContact CB-CE1 4.47Å; Q322-F363 HydrophobicContact CB-CZ 4.1Å; Q322-F363 VanDerWaalsContact O-CZ 3.27Å; Q322-F363 WeakPolarHBondContact O-CZ 3.32Å; R323-F363 HydrophobicContact CB-CE2 4.41Å; R323-F363 HydrophobicContact CG-CD2 4.34Å; R323-F363 HydrophobicContact CG-CE1 4.04Å; R323-F363 HydrophobicContact CG-CE2 3.76Å; R323-F363 HydrophobicContact CG-CZ 3.61Å; Y334-F363 AromaticContact CE1-CE1 3.82Å; Y334-F363 HydrophobicContact CE1-CE1 3.82Å; Y334-F363 HydrophobicContact CE1-CZ 4.38Å; Y334-F363 WeakPolarHBondContact OH-CD1 3.45Å; Y334-F363 WeakPolarHBondContact OH-CE1 3.27Å; Y334-F363 PolarHBondContact OH-N 2.94Å; K335-F363 WeakPolarHBondContact CE-O 3.28Å; K335-F363 PolarHBondContact NZ-O 3.01Å; Y361-F363 HydrophobicContact CD2-CD1 4.44Å; Y361-F363 HydrophobicContact CE2-CB 4.24Å; Y361-F363 HydrophobicContact CE2-CD1 4.29Å; Y361-F363 VanDerWaalsContact O-CD1 3.23Å; Y361-F363 WeakPolarHBondContact O-CD1 3.25Å; Y361-F363 PolarHBondContact O-N 2.79Å; F363-N365 VanDerWaalsContact CD2-O 3.23Å; F363-N365 WeakPolarHBondContact CD2-O 3.2Å; F363-Q385 HydrophobicContact CB-CB 4.18Å
364N81.1Confident69.9Low140 Ų14071.9 Ų71.975%0.74935%0.347SS*.  trans-85.4-32.4-174-68.1-32.1000113.3
365N64.5Low67Low74 Ų7479.8 Ų79.840%0.39638%0.384SS..  trans-93.3130.1-171.9-67.9-4.1000111.8F363 F383F363-N365 VanDerWaalsContact CD2-O 3.23Å; F363-N365 WeakPolarHBondContact CD2-O 3.2Å; N365-F383 WeakPolarHBondContact ND2-CD1 3.17Å; N365-F383 PolarHBondContact ND2-O 3Å
366H54.8Low64Low110 Ų11082.4 Ų82.451%0.50940%0.397SS..  trans-81.9152159.7-69-79.1000109.4R323 E368R323-H366 CarbonylContact O-C 3.59Å; H366-E368 HydrophobicContact CB-CG 4.32Å; H366-E368 PolarHBondContact O-N 2.72Å
367D52.6Low61.3Low18 Ų1887.2 Ų87.210%0.09642%0.418CS..  trans-64.147.1167.8-53.7-17.3000112R323 G324 S325 A369 F384R323-D367 WeakPolarHBondContact CB-OD1 3.36Å; R323-D367 WeakPolarHBondContact CB-OD2 3.4Å; R323-D367 VanDerWaalsContact O-CB 3.23Å; R323-D367 WeakPolarHBondContact O-CB 3.29Å; R323-D367 PolarHBondContact O-N 3.45Å; G324-D367 PolarHBondContact N-OD2 2.65Å; G324-D367 VanDerWaalsContact N-OD2 3.14Å; S325-D367 VanDerWaalsContact CB-OD2 3.24Å; S325-D367 WeakPolarHBondContact CB-OD2 3.22Å; S325-D367 PolarHBondContact N-OD2 2.9Å; S325-D367 VanDerWaalsContact OG-CG 3.31Å; S325-D367 PolarHBondContact OG-OD2 3.22Å; D367-A369 PolarHBondContact O-N 2.69Å; D367-F384 HydrophobicContact CB-CE1 3.85Å; D367-F384 HydrophobicContact CB-CZ 3.82Å; D367-F384 WeakPolarHBondContact OD1-CD1 3.38Å; D367-F384 WeakPolarHBondContact OD1-CE1 3.28Å; D367-F384 WeakPolarHBondContact OD1-CZ 3.2Å
368E39.9Very low58.5Low126 Ų12695.3 Ų95.359%0.58946%0.458SS*.  trans-73.267.5170.6-71-151.8139.400110.6H366 K370H366-E368 HydrophobicContact CB-CG 4.32Å; H366-E368 PolarHBondContact O-N 2.72Å; E368-K370 PolarHBondContact O-N 2.85Å; E368-K370 IonicContact OE1-NZ 3.88Å; E368-K370 PolarHBondContact OE1-NZ 3.1Å
369A38.6Very low55.6Low67 Ų67102.5 Ų102.555%0.55449%0.492SS*.  trans-66.461.9148.300000109.2D367 T371 L382D367-A369 PolarHBondContact O-N 2.69Å; A369-T371 VanDerWaalsContact C-N 3.33Å; A369-L382 HydrophobicContact CB-CD1 4.3Å; A369-L382 HydrophobicContact CB-CD2 4.03Å
370K33.5Very low52.7Low164 Ų164108.9 Ų108.971%0.71352%0.521SS*.  trans-93.117.7170.2-84.2-175.6-176.5153.80113.2E368E368-K370 PolarHBondContact O-N 2.85Å; E368-K370 IonicContact OE1-NZ 3.88Å; E368-K370 PolarHBondContact OE1-NZ 3.1Å
371T30.7Very low50.2Low120 Ų120113.4 Ų113.474%0.73654%0.541SS*.SBendtrans-127.483.8178.543.50000112.6A369 K373A369-T371 VanDerWaalsContact C-N 3.33Å; T371-K373 PolarHBondContact O-N 3.3Å; T371-K373 VanDerWaalsContact O-N 3.1Å
372Q31.8Very low48.1Very low193 Ų193116.4 Ų116.490%0.90256%0.557SS**  trans11.282.2134.7-166.4160.83.600117.9
373K33.6Very low46.2Very low161 Ų161115.5 Ų115.570%0.755%0.554SS**  trans172.2111.8137.4-110.5-178169-173.40110.2T371 E375T371-K373 PolarHBondContact O-N 3.3Å; T371-K373 VanDerWaalsContact O-N 3.1Å; K373-E375 VanDerWaalsContact C-N 3.26Å; K373-E375 PolarHBondContact O-N 3.33Å
374Y37.4Very low45.5Very low227 Ų227116.1 Ų116.189%0.8956%0.557SS**THydrogen-bonded Turntrans-73.41.1-175.9-84.6-88000116I376Y374-I376 VanDerWaalsContact C-N 3.28Å; Y374-I376 PolarHBondContact O-N 3.31Å
375E37.9Very low45.9Very low177 Ų177112.5 Ų112.583%0.82754%0.536SS*.THydrogen-bonded Turntrans-83.5-0.1-179-72-169.8156.700114.3K373K373-E375 VanDerWaalsContact C-N 3.26Å; K373-E375 PolarHBondContact O-N 3.33Å
376I35.5Very low47.2Very low57 Ų57109 Ų10929%0.29252%0.518SS..  trans-137.557.3-167.8-46.7174.1000112.3Y374 M378 Q379 H380Y374-I376 VanDerWaalsContact C-N 3.28Å; Y374-I376 PolarHBondContact O-N 3.31Å; I376-M378 PolarHBondContact O-N 3.12Å; I376-Q379 HydrophobicContact CG2-CB 3.17Å; I376-Q379 HydrophobicContact CG2-CG 3.42Å; I376-Q379 VanDerWaalsContact CG2-CG 3.42Å; I376-H380 PolarHBondContact O-N 3.12Å
377F42.6Very low49.1Very low104 Ų104104.2 Ų104.246%0.45650%0.496SS..THydrogen-bonded Turntrans-60.3-18.6163-145.5-101.7000111.7V185V185-F377 HydrophobicContact CG1-CD2 4.12Å; V185-F377 HydrophobicContact CG1-CE2 3.34Å; V185-F377 HydrophobicContact CG1-CZ 3.66Å
378M39.5Very low51.2Low171 Ų171104.4 Ų104.484%0.84250%0.498SS*.THydrogen-bonded Turntrans-93.7-30.9-177.2-79.3-88.6-91.900116.2I376I376-M378 PolarHBondContact O-N 3.12Å
379Q38.5Very low53.8Low152 Ų15299.8 Ų99.871%0.7148%0.48SS*.THydrogen-bonded Turntrans-97.5-25.4178.1-49.5174.4-41.300113.7I376I376-Q379 HydrophobicContact CG2-CB 3.17Å; I376-Q379 HydrophobicContact CG2-CG 3.42Å; I376-Q379 VanDerWaalsContact CG2-CG 3.42Å
380H38.1Very low56.5Low133 Ų133100.3 Ų100.362%0.61648%0.477SS*.SBendtrans-108.668.4172.7-72.3-109.8000108.1I376 L382I376-H380 PolarHBondContact O-N 3.12Å; H380-L382 VanDerWaalsContact C-N 3.32Å; H380-L382 PolarHBondContact O-N 3.49Å
381K43.2Very low59.3Low95 Ų9593.5 Ų93.541%0.41345%0.453SS..  trans-43.998.9165-78.1179.4174.2-167.80108.1E76 V77 N78 F383E76-K381 PolarHBondContact O-NZ 2.74Å; V77-K381 HydrophobicContact CB-CD 4.48Å; V77-K381 HydrophobicContact CG1-CB 3.62Å; V77-K381 HydrophobicContact CG1-CD 3.7Å; V77-K381 HydrophobicContact CG1-CG 3.79Å; N78-K381 VanDerWaalsContact OD1-CD 3.28Å; N78-K381 WeakPolarHBondContact OD1-CD 3.49Å; K381-F383 PolarHBondContact O-N 2.98Å
382L52.8Low62.2Low65 Ų6591.7 Ų91.734%0.3445%0.445SS..  trans-60.997.8166.5-73.9169000105.3A369 H380 F384A369-L382 HydrophobicContact CB-CD1 4.3Å; A369-L382 HydrophobicContact CB-CD2 4.03Å; H380-L382 VanDerWaalsContact C-N 3.32Å; H380-L382 PolarHBondContact O-N 3.49Å; L382-F384 HydrophobicContact CB-CD2 4.06Å; L382-F384 HydrophobicContact CB-CE1 4.21Å; L382-F384 HydrophobicContact CB-CE2 3.39Å; L382-F384 HydrophobicContact CB-CZ 3.5Å; L382-F384 HydrophobicContact CD1-CE2 3.99Å; L382-F384 HydrophobicContact CD1-CZ 4.01Å; L382-F384 HydrophobicContact CD2-CZ 4.13Å; L382-F384 HydrophobicContact CG-CE2 4.23Å; L382-F384 HydrophobicContact CG-CZ 4.09Å; L382-F384 PolarHBondContact O-N 2.69Å
383F54.9Low65Low61 Ų6186 Ų8627%0.26843%0.425SS..  trans-76.298.4-176.3177.4-105.7000108.2V77 N78 D80 N365 K381V77-F383 HydrophobicContact CG1-CD2 4.36Å; V77-F383 WeakPolarHBondContact O-CD2 3.29Å; V77-F383 VanDerWaalsContact O-CE2 3.26Å; V77-F383 WeakPolarHBondContact O-CE2 3.25Å; N78-F383 HydrophobicContact CB-CD2 3.68Å; N78-F383 HydrophobicContact CB-CE2 4.05Å; N78-F383 HydrophobicContact CB-CG 4.36Å; D80-F383 HydrophobicContact CB-CE2 3.59Å; D80-F383 HydrophobicContact CB-CZ 3.87Å; N365-F383 WeakPolarHBondContact ND2-CD1 3.17Å; N365-F383 PolarHBondContact ND2-O 3Å; K381-F383 PolarHBondContact O-N 2.98Å
384F74.9Confident67.8Low23 Ų2386.4 Ų86.410%0.10142%0.423CS..  trans-101123.7171.2-58.9-46000109.2S82 W84 D367 L382S82-F384 VanDerWaalsContact CA-O 3.25Å; S82-F384 WeakPolarHBondContact CA-O 3.44Å; S82-F384 WeakPolarHBondContact CB-O 3.09Å; S82-F384 PolarHBondContact OG-O 3Å; W84-F384 AromaticContact CD1-CD2 3.58Å; W84-F384 AromaticContact NE1-CD2 3.54Å; D367-F384 HydrophobicContact CB-CE1 3.85Å; D367-F384 HydrophobicContact CB-CZ 3.82Å; D367-F384 WeakPolarHBondContact OD1-CD1 3.38Å; D367-F384 WeakPolarHBondContact OD1-CE1 3.28Å; D367-F384 WeakPolarHBondContact OD1-CZ 3.2Å; L382-F384 HydrophobicContact CB-CD2 4.06Å; L382-F384 HydrophobicContact CB-CE1 4.21Å; L382-F384 HydrophobicContact CB-CE2 3.39Å; L382-F384 HydrophobicContact CB-CZ 3.5Å; L382-F384 HydrophobicContact CD1-CE2 3.99Å; L382-F384 HydrophobicContact CD1-CZ 4.01Å; L382-F384 HydrophobicContact CD2-CZ 4.13Å; L382-F384 HydrophobicContact CG-CE2 4.23Å; L382-F384 HydrophobicContact CG-CZ 4.09Å; L382-F384 PolarHBondContact O-N 2.69Å
385Q87.8Confident70.5Confident64 Ų6476.1 Ų76.130%0.29938%0.383SS..  trans-63137.3-176.1-163.7168.313.400110Y361 F363Y361-Q385 PolarHBondContact OH-O 3.03Å; Y361-Q385 VanDerWaalsContact OH-O 3.1Å; F363-Q385 HydrophobicContact CB-CB 4.18Å
386G92.2Very high73.2Confident2 Ų272.2 Ų72.22%0.02137%0.367CS..  trans-69.9175.4166.600000112D80 R81 Y361D80-G386 PolarHBondContact OD2-N 3.5Å; R81-G386 WeakPolarHBondContact O-CA 3.39Å; Y361-G386 VanDerWaalsContact CE2-O 3.23Å; Y361-G386 WeakPolarHBondContact CE2-O 3.43Å
387P95.4Very high76.2Confident8 Ų869.6 Ų69.65%0.05235%0.354CS..SBendtrans-63.9164168.432.3-36.7000110.4E42 R97 Y361 S389 T397 W414E42-P387 HydrophobicContact CB-CB 3.71Å; E42-P387 HydrophobicContact CB-CG 4Å; E42-P387 HydrophobicContact CG-CB 4.22Å; E42-P387 HydrophobicContact CG-CG 4.25Å; E42-P387 WeakPolarHBondContact OE2-CD 3.2Å; E42-P387 VanDerWaalsContact OE2-CG 3.29Å; E42-P387 WeakPolarHBondContact OE2-CG 3.48Å; R97-P387 VanDerWaalsContact NH1-CD 3.32Å; Y361-P387 HydrophobicContact CD1-CB 4.1Å; Y361-P387 HydrophobicContact CE1-CB 4.04Å; P387-S389 PolarHBondContact O-N 3.2Å; P387-T397 HydrophobicContact CB-CG2 4.36Å; P387-T397 HydrophobicContact CG-CG2 4.37Å; P387-W414 HydrophobicContact CB-CH2 4.16Å
388P96.3Very high78.8Confident22 Ų2267.5 Ų67.514%0.14335%0.347CS..SBendtrans-50.4127170.7-25.535.2000110.4T397 N398 S412 W414P388-T397 CarbonylContact O-C 3.52Å; P388-T397 WeakPolarHBondContact O-CA 3.39Å; P388-N398 HydrophobicContact CB-CB 4.16Å; P388-N398 PolarHBondContact O-N 2.82Å; P388-S412 WeakPolarHBondContact CB-O 3.43Å; P388-W414 HydrophobicContact CG-CD2 4.36Å
389S95.6Very high81.6Confident30 Ų3061.5 Ų61.521%0.2132%0.322CS..BIsolated β-bridgetrans-147.1171.6-177.373.70000112.9P387 G391 I396 N398P387-S389 PolarHBondContact O-N 3.2Å; S389-G391 PolarHBondContact O-N 2.9Å; S389-G391 PolarHBondContact OG-N 3.27Å; S389-I396 CarbonylContact C-O 3.56Å; S389-I396 WeakPolarHBondContact CA-O 3.43Å; S389-I396 VanDerWaalsContact CB-O 3.25Å; S389-I396 WeakPolarHBondContact CB-O 3.31Å; S389-N398 VanDerWaalsContact C-OD1 3.25Å; S389-N398 PolarHBondContact N-ND2 3.46Å; S389-N398 PolarHBondContact O-ND2 3.12Å
390T95.2Very high84.4Confident78 Ų7854.9 Ų54.948%0.47929%0.292SS..  trans-68.2-8.517356.30000113.8I396 N398T390-I396 HydrophobicContact CG2-CB 4.03Å; T390-I396 PolarHBondContact N-O 2.77Å; T390-I396 PolarHBondContact OG1-N 2.81Å; T390-N398 PolarHBondContact N-OD1 3.21Å
391G92.1Very high87.3Confident21 Ų2151.4 Ų51.422%0.21628%0.281CS..  trans70.6-168.9-176.600000113.6S389 Y394 F395S389-G391 PolarHBondContact O-N 2.9Å; S389-G391 PolarHBondContact OG-N 3.27Å; G391-Y394 PolarHBondContact O-N 3.5Å; G391-Y394 VanDerWaalsContact O-N 3.1Å; G391-F395 PolarHBondContact O-N 3.38Å
392S91.4Very high89.9Confident81 Ų8150.5 Ų50.557%0.56628%0.277SS*.THydrogen-bonded Turntrans-59.6140.9-177.4172.70000113F395S392-F395 VanDerWaalsContact CA-CE2 3.47Å
393P90.6Very high92Very high74 Ų7450 Ų5048%0.48127%0.274SS..THydrogen-bonded Turncis-91.1-4.20.235.3-35.7000114.4R81R81-P393 PolarHBondContact NH2-O 3.06Å
394Y91.7Very high93.8Very high169 Ų16952.5 Ų52.566%0.66330%0.3SS*.THydrogen-bonded Turntrans-94-38.3-163.5-57.7-68.2000114.1G391 I396G391-Y394 PolarHBondContact O-N 3.5Å; G391-Y394 VanDerWaalsContact O-N 3.1Å; Y394-I396 VanDerWaalsContact C-N 3.25Å; Y394-I396 PolarHBondContact O-N 3.09Å
395F94.6Very high94.5Very high12 Ų1257.2 Ų57.25%0.05332%0.322CS..  trans51.742.3-179-61.4-87.7000113.4E76 G79 R81 G391 S392 T397E76-F395 HydrophobicContact CG-CE2 3.77Å; E76-F395 HydrophobicContact CG-CZ 3.84Å; E76-F395 VanDerWaalsContact OE1-CE2 3.29Å; E76-F395 WeakPolarHBondContact OE1-CE2 3.33Å; G79-F395 WeakPolarHBondContact O-CZ 3.49Å; R81-F395 HydrophobicContact CB-CD1 4.19Å; R81-F395 HydrophobicContact CB-CG 4.28Å; R81-F395 HydrophobicContact CG-CB 4.14Å; R81-F395 HydrophobicContact CG-CD1 3.94Å; R81-F395 HydrophobicContact CG-CD2 3.83Å; R81-F395 HydrophobicContact CG-CE1 4.3Å; R81-F395 HydrophobicContact CG-CE2 4.16Å; R81-F395 HydrophobicContact CG-CG 3.69Å; R81-F395 HydrophobicContact CG-CZ 4.38Å; R81-F395 VanDerWaalsContact NE-CD2 3.28Å; G391-F395 PolarHBondContact O-N 3.38Å; S392-F395 VanDerWaalsContact CA-CE2 3.47Å; F395-T397 PolarHBondContact O-N 3.39Å
396I95.1Very high94.8Very high94 Ų9455.3 Ų55.348%0.48232%0.319SS..PPolyproline II helixtrans-69.9125.1173.7-59.9169000107.1S389 T390 Y394 N398S389-I396 CarbonylContact C-O 3.56Å; S389-I396 WeakPolarHBondContact CA-O 3.43Å; S389-I396 VanDerWaalsContact CB-O 3.25Å; S389-I396 WeakPolarHBondContact CB-O 3.31Å; T390-I396 HydrophobicContact CG2-CB 4.03Å; T390-I396 PolarHBondContact N-O 2.77Å; T390-I396 PolarHBondContact OG1-N 2.81Å; Y394-I396 VanDerWaalsContact C-N 3.25Å; Y394-I396 PolarHBondContact O-N 3.09Å; I396-N398 PolarHBondContact O-N 3.42Å
397T97.4Very high95Very high3 Ų357.8 Ų57.82%0.01833%0.33CS..BIsolated β-bridgetrans-58.8128.3177.2-52.40000110.4R44 R97 P387 P388 F395 W414R44-T397 VanDerWaalsContact CD-O 3.28Å; R44-T397 WeakPolarHBondContact CD-O 3.37Å; R44-T397 HydrophobicContact CG-CG2 4.18Å; R97-T397 PolarHBondContact O-OG1 2.72Å; P387-T397 HydrophobicContact CB-CG2 4.36Å; P387-T397 HydrophobicContact CG-CG2 4.37Å; P388-T397 CarbonylContact O-C 3.52Å; P388-T397 WeakPolarHBondContact O-CA 3.39Å; F395-T397 PolarHBondContact O-N 3.39Å; T397-W414 HydrophobicContact CG2-CH2 4.17Å; T397-W414 HydrophobicContact CG2-CZ2 3.77Å
398N97.7Very high95.1Very high60 Ų6058 Ų5832%0.32133%0.332SS..PPolyproline II helixtrans-78.4138.7179.3-64.7-20.1000110.1P388 S389 T390 I396 W414P388-N398 HydrophobicContact CB-CB 4.16Å; P388-N398 PolarHBondContact O-N 2.82Å; S389-N398 VanDerWaalsContact C-OD1 3.25Å; S389-N398 PolarHBondContact N-ND2 3.46Å; S389-N398 PolarHBondContact O-ND2 3.12Å; T390-N398 PolarHBondContact N-OD1 3.21Å; I396-N398 PolarHBondContact O-N 3.42Å; N398-W414 WeakPolarHBondContact O-CZ2 3.34Å; N398-W414 PolarHBondContact O-NE1 2.82Å
399S98.2Very high95.2Very high45 Ų4560.5 Ų60.532%0.31534%0.342SS..PPolyproline II helixtrans-69.1146.5172.2-61.30000111.7D47D47-S399 VanDerWaalsContact CG-OG 3.29Å; D47-S399 WeakPolarHBondContact OD1-CB 3.18Å; D47-S399 PolarHBondContact OD1-OG 2.86Å; D47-S399 WeakPolarHBondContact OD2-CA 3.36Å; D47-S399 PolarHBondContact OD2-OG 2.82Å; D47-S399 VanDerWaalsContact OD2-OG 3.09Å
400P98.2Very high95.1Very high12 Ų1266 Ų668%0.07836%0.364CS..PPolyproline II helixtrans-65.4145169.726.1-30.6000111.3W43 F402 W414W43-P400 HydrophobicContact CE3-CG 3.97Å; W43-P400 HydrophobicContact CH2-CB 4.16Å; W43-P400 HydrophobicContact CH2-CG 3.59Å; W43-P400 HydrophobicContact CZ2-CG 4.2Å; W43-P400 HydrophobicContact CZ3-CG 3.47Å; W43-P400 VanDerWaalsContact CZ3-CG 3.47Å; P400-F402 HydrophobicContact CB-CE1 4.1Å; P400-F402 HydrophobicContact CB-CZ 4.07Å; P400-F402 HydrophobicContact CG-CE1 4.45Å; P400-F402 HydrophobicContact CG-CZ 3.99Å; P400-W414 VanDerWaalsContact CA-CD1 3.42Å; P400-W414 HydrophobicContact CB-CB 4.18Å; P400-W414 HydrophobicContact CB-CG 3.89Å
401T98.2Very high95.1Very high61 Ų6168.6 Ų68.637%0.37438%0.379SS..  trans-118.1148.8170.659.80000109.2C408 E409 S412T401-C408 CarbonylContact O-C 3.47Å; T401-C408 WeakPolarHBondContact O-CA 3.36Å; T401-E409 VanDerWaalsContact CB-OE2 3.27Å; T401-E409 WeakPolarHBondContact CB-OE2 3.22Å; T401-E409 PolarHBondContact O-N 2.66Å; T401-E409 PolarHBondContact OG1-OE2 2.67Å; T401-S412 WeakPolarHBondContact OG1-CB 3.46Å
402F98Very high95.3Very high76 Ų7668.1 Ų68.133%0.33337%0.373SS..BIsolated β-bridgetrans-121.3141.2-170.7-47.6-72.1000111.9P400 H407 C408 R419P400-F402 HydrophobicContact CB-CE1 4.1Å; P400-F402 HydrophobicContact CB-CZ 4.07Å; P400-F402 HydrophobicContact CG-CE1 4.45Å; P400-F402 HydrophobicContact CG-CZ 3.99Å; F402-H407 CarbonylContact C-O 3.4Å; F402-H407 WeakPolarHBondContact CA-O 3.37Å; F402-C408 WeakPolarHBondContact CE1-SG 3.32Å; F402-R419 VanDerWaalsContact CE1-CD 3.4Å; F402-R419 VanDerWaalsContact CZ-CZ 3.48Å
403N96.2Very high95.6Very high53 Ų5365.1 Ų65.128%0.28336%0.355SS..  trans-79.5-179.1173.368.48.6000112E405 G406 H407 E409N403-E405 PolarHBondContact ND2-OE2 3.46Å; N403-E405 VanDerWaalsContact ND2-OE2 3.11Å; N403-E405 PolarHBondContact O-N 2.98Å; N403-E405 WeakPolarHBondContact OD1-CA 3.45Å; N403-E405 PolarHBondContact OD1-N 3.1Å; N403-E405 VanDerWaalsContact OD1-N 3.09Å; N403-E405 PolarHBondContact OD1-OE2 3.03Å; N403-G406 PolarHBondContact O-N 2.68Å; N403-G406 PolarHBondContact OD1-N 3.02Å; N403-H407 PolarHBondContact N-O 3.38Å; N403-H407 PolarHBondContact OD1-N 3.31Å; N403-H407 PolarHBondContact OD1-O 2.84Å; N403-E409 HydrophobicContact CB-CG 4.21Å
404S93.7Very high95.9Very high115 Ų11561.6 Ų61.680%0.80433%0.332SS*.THydrogen-bonded Turntrans-60.2-25.4178.139.20000114.1G406S404-G406 VanDerWaalsContact C-N 3.31Å
405E89.3Confident96.2Very high122 Ų12253.7 Ų53.757%0.5730%0.301SS*.THydrogen-bonded Turntrans-85.8-4.3177.1-60.670.2-135.200112.7N403N403-E405 PolarHBondContact ND2-OE2 3.46Å; N403-E405 VanDerWaalsContact ND2-OE2 3.11Å; N403-E405 PolarHBondContact O-N 2.98Å; N403-E405 WeakPolarHBondContact OD1-CA 3.45Å; N403-E405 PolarHBondContact OD1-N 3.1Å; N403-E405 VanDerWaalsContact OD1-N 3.09Å; N403-E405 PolarHBondContact OD1-OE2 3.03Å
406G94.1Very high96.4Very high23 Ų2353.1 Ų53.124%0.23730%0.299CS..SBendtrans80.810.3-179.300000114.7N403 S404 R419N403-G406 PolarHBondContact O-N 2.68Å; N403-G406 PolarHBondContact OD1-N 3.02Å; S404-G406 VanDerWaalsContact C-N 3.31Å; G406-R419 PolarHBondContact O-NH1 2.87Å
407H96.1Very high96.6Very high54 Ų5448.7 Ų48.725%0.2528%0.276CS..PPolyproline II helixtrans-83.6154.1173.1-55.6162.4000110.3F402 N403 E409 R419 S421F402-H407 CarbonylContact C-O 3.4Å; F402-H407 WeakPolarHBondContact CA-O 3.37Å; N403-H407 PolarHBondContact N-O 3.38Å; N403-H407 PolarHBondContact OD1-N 3.31Å; N403-H407 PolarHBondContact OD1-O 2.84Å; H407-E409 PolarHBondContact O-N 2.94Å; H407-R419 PolarHBondContact CD2-O 3.28Å; H407-S421 PolarHBondContact CE1-OG 3.12Å; H407-S421 PolarHBondContact NE2-OG 3.42Å
408C97.7Very high96.6Very high13 Ų1348.6 Ų48.69%0.08828%0.275CS..BIsolated β-bridgetrans-65.4130.2173-75.90000110.9T401 F402 Q410 W414 C416T401-C408 CarbonylContact O-C 3.47Å; T401-C408 WeakPolarHBondContact O-CA 3.36Å; F402-C408 WeakPolarHBondContact CE1-SG 3.32Å; C408-Q410 PolarHBondContact O-N 3.33Å; C408-W414 HydrophobicContact CB-CB 4.25Å; C408-W414 WeakPolarHBondContact CB-O 3.41Å; C408-C416 HydrophobicContact CB-CB 3.63Å; C408-C416 WeakPolarHBondContact CB-SG 3.24Å; C408-C416 WeakPolarHBondContact SG-CB 3.39Å; C408-C416 CovalentContact SG-SG 2.01Å; C408-C416 PolarHBondContact SG-SG 3.2Å
409E97.6Very high96.6Very high75 Ų7546.6 Ų46.635%0.3526%0.263SS..PPolyproline II helixtrans-65.6130.5172.3-62-177.8136.300108.3T401 N403 H407 T411 S412T401-E409 VanDerWaalsContact CB-OE2 3.27Å; T401-E409 WeakPolarHBondContact CB-OE2 3.22Å; T401-E409 PolarHBondContact O-N 2.66Å; T401-E409 PolarHBondContact OG1-OE2 2.67Å; N403-E409 HydrophobicContact CB-CG 4.21Å; H407-E409 PolarHBondContact O-N 2.94Å; E409-T411 PolarHBondContact O-N 3.2Å; E409-S412 VanDerWaalsContact O-CB 3.32Å; E409-S412 WeakPolarHBondContact O-CB 3.19Å; E409-S412 PolarHBondContact O-N 3.31Å; E409-S412 PolarHBondContact O-OG 2.87Å
410Q94Very high96.6Very high146 Ų14646.9 Ų46.968%0.68226%0.257SS*.G310 helixtrans-56.2-30.2180-171.9178.24.700112.2Y362 C408 S412 G413Y362-Q410 HydrophobicContact CD2-CG 4.38Å; Y362-Q410 HydrophobicContact CE2-CB 4.39Å; Y362-Q410 HydrophobicContact CE2-CG 3.9Å; C408-Q410 PolarHBondContact O-N 3.33Å; Q410-S412 VanDerWaalsContact C-N 3.26Å; Q410-S412 PolarHBondContact O-N 3.03Å; Q410-G413 PolarHBondContact O-N 2.86Å; Q410-G413 VanDerWaalsContact O-N 3.11Å
411T95.5Very high96.4Very high131 Ų13149.2 Ų49.280%0.80427%0.274SS*.G310 helixtrans-65.9-22.1176.245.30000114.1E409 G413E409-T411 PolarHBondContact O-N 3.2Å; T411-G413 PolarHBondContact O-N 3.06Å
412S96.6Very high96.3Very high12 Ų1248.2 Ų48.28%0.08427%0.268CS..G310 helixtrans-71.7-18.3172.873.80000112.7P388 T401 E409 Q410 W414P388-S412 WeakPolarHBondContact CB-O 3.43Å; T401-S412 WeakPolarHBondContact OG1-CB 3.46Å; E409-S412 VanDerWaalsContact O-CB 3.32Å; E409-S412 WeakPolarHBondContact O-CB 3.19Å; E409-S412 PolarHBondContact O-N 3.31Å; E409-S412 PolarHBondContact O-OG 2.87Å; Q410-S412 VanDerWaalsContact C-N 3.26Å; Q410-S412 PolarHBondContact O-N 3.03Å; S412-W414 VanDerWaalsContact C-N 3.27Å; S412-W414 PolarHBondContact O-N 3.41Å; S412-W414 PolarHBondContact OG-N 2.88Å
413G96.2Very high96.3Very high17 Ų1744.7 Ų44.718%0.17525%0.252CS..SBendtrans82.9-6.1-175.200000114.5Y361 Y362 Q410 T411Y361-G413 WeakPolarHBondContact CA-O 3.38Å; Y361-G413 WeakPolarHBondContact CB-O 3.23Å; Y362-G413 WeakPolarHBondContact CD2-O 3.37Å; Y362-G413 PolarHBondContact N-O 2.81Å; Q410-G413 PolarHBondContact O-N 2.86Å; Q410-G413 VanDerWaalsContact O-N 3.11Å; T411-G413 PolarHBondContact O-N 3.06Å
414W98.3Very high96.3Very high0 Ų046.2 Ų46.20%025%0.254CS..BIsolated β-bridgetrans-92143.6178.4-60.894.8000112.5F41 E42 W43 Y361 Y362 P387 P388 T397 N398 P400 C408 S412 C416F41-W414 WeakPolarHBondContact O-CZ3 3.29Å; E42-W414 HydrophobicContact CB-CH2 4.25Å; W43-W414 AromaticContact CD1-CE3 3.92Å; W43-W414 AromaticContact CD1-CH2 3.86Å; W43-W414 AromaticContact CD1-CZ3 3.38Å; W43-W414 HydrophobicContact CG-CH2 4.34Å; W43-W414 HydrophobicContact CG-CZ3 4.22Å; W43-W414 AromaticContact NE1-CE3 3.49Å; W43-W414 AromaticContact NE1-CZ3 3.46Å; Y361-W414 HydrophobicContact CD1-CZ3 4.13Å; Y362-W414 VanDerWaalsContact CE2-O 3.24Å; Y362-W414 WeakPolarHBondContact CE2-O 3.46Å; P387-W414 HydrophobicContact CB-CH2 4.16Å; P388-W414 HydrophobicContact CG-CD2 4.36Å; T397-W414 HydrophobicContact CG2-CH2 4.17Å; T397-W414 HydrophobicContact CG2-CZ2 3.77Å; N398-W414 WeakPolarHBondContact O-CZ2 3.34Å; N398-W414 PolarHBondContact O-NE1 2.82Å; P400-W414 VanDerWaalsContact CA-CD1 3.42Å; P400-W414 HydrophobicContact CB-CB 4.18Å; P400-W414 HydrophobicContact CB-CG 3.89Å; C408-W414 HydrophobicContact CB-CB 4.25Å; C408-W414 WeakPolarHBondContact CB-O 3.41Å; S412-W414 VanDerWaalsContact C-N 3.27Å; S412-W414 PolarHBondContact O-N 3.41Å; S412-W414 PolarHBondContact OG-N 2.88Å; W414-C416 VanDerWaalsContact CB-SG 3.58Å
415V98.1Very high96.4Very high4 Ų442.8 Ų42.82%0.02422%0.224CC..  trans-89.8-45178.7179.20000111Y334 S360 Y362 E417 W420Y334-V415 HydrophobicContact CD1-CG1 4.28Å; Y334-V415 HydrophobicContact CD1-CG2 4.19Å; Y334-V415 HydrophobicContact CD2-CG1 3.84Å; Y334-V415 HydrophobicContact CD2-CG2 3.83Å; Y334-V415 HydrophobicContact CE1-CG2 4.06Å; Y334-V415 HydrophobicContact CE2-CG2 3.71Å; Y334-V415 HydrophobicContact CG-CB 4.45Å; Y334-V415 HydrophobicContact CG-CG1 3.7Å; Y334-V415 HydrophobicContact CG-CG2 4.09Å; S360-V415 WeakPolarHBondContact O-CB 3.35Å; S360-V415 PolarHBondContact O-N 2.87Å; Y362-V415 HydrophobicContact CD1-CG2 3.77Å; Y362-V415 HydrophobicContact CD2-CG2 4.02Å; Y362-V415 HydrophobicContact CE1-CG2 3.78Å; Y362-V415 HydrophobicContact CE2-CG2 4.01Å; Y362-V415 HydrophobicContact CG-CG2 3.89Å; V415-E417 VanDerWaalsContact CG1-CD 3.47Å; V415-E417 HydrophobicContact CG1-CG 3.69Å; V415-E417 WeakPolarHBondContact CG1-OE2 3.38Å; V415-W420 HydrophobicContact CG1-CZ2 3.89Å; V415-W420 PolarHBondContact O-NE1 2.87Å
416C98.3Very high96.8Very high0 Ų037 Ų370%020%0.197CC..  trans53.156.1178.9-49.80000112.9C408 W414 H418 R419 W420C408-C416 HydrophobicContact CB-CB 3.63Å; C408-C416 WeakPolarHBondContact CB-SG 3.24Å; C408-C416 WeakPolarHBondContact SG-CB 3.39Å; C408-C416 CovalentContact SG-SG 2.01Å; C408-C416 PolarHBondContact SG-SG 3.2Å; W414-C416 VanDerWaalsContact CB-SG 3.58Å; C416-H418 PolarHBondContact O-N 3.48Å; C416-R419 HydrophobicContact CB-CB 3.98Å; C416-R419 HydrophobicContact CB-CG 4.32Å; C416-R419 WeakPolarHBondContact O-CA 3.22Å; C416-R419 WeakPolarHBondContact O-CB 3.47Å; C416-R419 PolarHBondContact O-N 3.16Å; C416-W420 VanDerWaalsContact O-CD1 3.32Å
417E98.5Very high97Very high1 Ų135.9 Ų35.91%0.00519%0.185CC..G310 helixtrans-54.8-35.4-179.8-58.687.9137.300111.5Q322 Y334 Y340 M358 S359 S360 V415 R419 W420 I423Q322-E417 PolarHBondContact NE2-OE1 3.47Å; Y334-E417 WeakPolarHBondContact CD1-OE1 3.45Å; Y340-E417 HydrophobicContact CE1-CB 4.12Å; Y340-E417 HydrophobicContact CE1-CG 3.94Å; M358-E417 WeakPolarHBondContact O-CB 3.27Å; S359-E417 WeakPolarHBondContact CA-OE2 3.34Å; S360-E417 WeakPolarHBondContact CB-OE1 3.48Å; S360-E417 PolarHBondContact N-OE2 3.22Å; V415-E417 VanDerWaalsContact CG1-CD 3.47Å; V415-E417 HydrophobicContact CG1-CG 3.69Å; V415-E417 WeakPolarHBondContact CG1-OE2 3.38Å; E417-R419 PolarHBondContact O-N 3.16Å; E417-W420 HydrophobicContact CG-CZ2 4.13Å; E417-W420 VanDerWaalsContact O-CB 3.32Å; E417-W420 WeakPolarHBondContact O-CB 3.39Å; E417-W420 PolarHBondContact O-N 3.39Å; E417-I423 HydrophobicContact CB-CD1 4.21Å; E417-I423 VanDerWaalsContact O-CD1 3.28Å; E417-I423 WeakPolarHBondContact O-CD1 3.42Å
418H98.4Very high97.1Very high0 Ų035.4 Ų35.40%018%0.184CC..G310 helixtrans-62.8-21.3174.570.3-63000114V38 W43 E51 Y55 I357 S359 C416V38-H418 HydrophobicContact CG2-CB 3.73Å; W43-H418 AromaticContact CH2-CE1 3.94Å; W43-H418 AromaticContact CZ2-CE1 3.8Å; E51-H418 IonicContact OE1-CD2 2.7Å; E51-H418 PolarHBondContact OE1-CD2 3.15Å; E51-H418 IonicContact OE1-CE1 3.56Å; E51-H418 IonicContact OE1-NE2 3.43Å; E51-H418 PolarHBondContact OE1-NE2 2.89Å; Y55-H418 AromaticContact CE1-CD2 3.83Å; Y55-H418 PolarHBondContact OH-O 2.78Å; I357-H418 HydrophobicContact CD1-CB 3.62Å; I357-H418 HydrophobicContact CG1-CB 4.38Å; S359-H418 VanDerWaalsContact CB-ND1 3.28Å; S359-H418 WeakPolarHBondContact CB-ND1 3.34Å; S359-H418 PolarHBondContact OG-CE1 3.01Å; S359-H418 PolarHBondContact OG-ND1 3.03Å; S359-H418 VanDerWaalsContact OG-ND1 3.12Å; C416-H418 PolarHBondContact O-N 3.48Å
419R97.8Very high97.2Very high19 Ų1934.8 Ų34.87%0.07218%0.18CC..G310 helixtrans-88-9.8174.3-78176.3166.5-98.26.9114.3E51 Y55 F402 G406 H407 C416 E417 S421E51-R419 VanDerWaalsContact CD-NH2 3.33Å; E51-R419 IonicContact OE1-CZ 3.82Å; E51-R419 IonicContact OE1-NE 3.51Å; E51-R419 PolarHBondContact OE1-NE 2.96Å; E51-R419 IonicContact OE1-NH2 3.32Å; E51-R419 PolarHBondContact OE1-NH2 3.41Å; E51-R419 IonicContact OE2-CZ 2.61Å; E51-R419 VanDerWaalsContact OE2-CZ 3.31Å; E51-R419 IonicContact OE2-NE 2.8Å; E51-R419 PolarHBondContact OE2-NE 2.81Å; E51-R419 VanDerWaalsContact OE2-NE 3.14Å; E51-R419 IonicContact OE2-NH2 3.17Å; E51-R419 PolarHBondContact OE2-NH2 3.21Å; Y55-R419 HydrophobicContact CD1-CG 4.1Å; Y55-R419 HydrophobicContact CD2-CG 4.29Å; Y55-R419 HydrophobicContact CE1-CG 3.77Å; Y55-R419 HydrophobicContact CE2-CG 3.96Å; Y55-R419 HydrophobicContact CG-CG 4.37Å; Y55-R419 WeakPolarHBondContact OH-CA 3.32Å; F402-R419 VanDerWaalsContact CE1-CD 3.4Å; F402-R419 VanDerWaalsContact CZ-CZ 3.48Å; G406-R419 PolarHBondContact O-NH1 2.87Å; H407-R419 PolarHBondContact CD2-O 3.28Å; C416-R419 HydrophobicContact CB-CB 3.98Å; C416-R419 HydrophobicContact CB-CG 4.32Å; C416-R419 WeakPolarHBondContact O-CA 3.22Å; C416-R419 WeakPolarHBondContact O-CB 3.47Å; C416-R419 PolarHBondContact O-N 3.16Å; E417-R419 PolarHBondContact O-N 3.16Å; R419-S421 PolarHBondContact O-N 2.96Å
420W97Very high97.2Very high50 Ų5032.3 Ų32.319%0.18917%0.168CC..SBendtrans-61.4128.8176.5-65.76.7000109.2Y340 V415 C416 E417 T422 I423 R424Y340-W420 HydrophobicContact CD1-CH2 4.24Å; Y340-W420 AromaticContact CD1-CZ3 3.83Å; Y340-W420 HydrophobicContact CD1-CZ3 3.83Å; Y340-W420 HydrophobicContact CE1-CZ3 4.32Å; V415-W420 HydrophobicContact CG1-CZ2 3.89Å; V415-W420 PolarHBondContact O-NE1 2.87Å; C416-W420 VanDerWaalsContact O-CD1 3.32Å; E417-W420 HydrophobicContact CG-CZ2 4.13Å; E417-W420 VanDerWaalsContact O-CB 3.32Å; E417-W420 WeakPolarHBondContact O-CB 3.39Å; E417-W420 PolarHBondContact O-N 3.39Å; W420-T422 PolarHBondContact O-N 3.14Å; W420-T422 VanDerWaalsContact O-N 3.08Å; W420-I423 HydrophobicContact CB-CB 4.31Å; W420-I423 HydrophobicContact CB-CD1 4.33Å; W420-I423 HydrophobicContact CB-CG1 4.34Å; W420-I423 HydrophobicContact CD2-CD1 4.36Å; W420-I423 HydrophobicContact CE3-CD1 3.9Å; W420-I423 PolarHBondContact O-N 3.19Å; W420-R424 PolarHBondContact O-N 3.41Å
421S94.7Very high97.4Very high61 Ų6126.5 Ų26.543%0.42714%0.143SC..Hα-helixtrans-50.9-43.7-172.9-59.30000111.8H407 R419 R424 R425H407-S421 PolarHBondContact CE1-OG 3.12Å; H407-S421 PolarHBondContact NE2-OG 3.42Å; R419-S421 PolarHBondContact O-N 2.96Å; S421-R424 PolarHBondContact O-N 3.07Å; S421-R425 WeakPolarHBondContact O-CG 3.46Å; S421-R425 PolarHBondContact O-N 2.87Å
422T95.4Very high97.6Very high41 Ų4123.7 Ų23.725%0.25212%0.121SC..Hα-helixtrans-65.7-41.5-179.7560000112.8F341 W420 R425 M426 V485F341-T422 VanDerWaalsContact CD2-OG1 3.24Å; F341-T422 WeakPolarHBondContact CD2-OG1 3.38Å; F341-T422 HydrophobicContact CE1-CG2 4.46Å; F341-T422 HydrophobicContact CE2-CG2 4.42Å; F341-T422 HydrophobicContact CZ-CG2 4.31Å; W420-T422 PolarHBondContact O-N 3.14Å; W420-T422 VanDerWaalsContact O-N 3.08Å; T422-R425 PolarHBondContact O-N 2.67Å; T422-M426 WeakPolarHBondContact O-CG 3.3Å; T422-M426 PolarHBondContact O-N 3.29Å; T422-M426 VanDerWaalsContact O-N 3.08Å; T422-V485 HydrophobicContact CG2-CG1 4.38Å
423I97.9Very high97.6Very high1 Ų123.1 Ų23.11%0.00512%0.117CC..Hα-helixtrans-66.6-47.2176.2-68.4177.9000110.2Y340 F341 V344 I357 E417 W420 R425 M426 T427Y340-I423 HydrophobicContact CE1-CD1 3.98Å; F341-I423 HydrophobicContact CD2-CG1 4Å; V344-I423 HydrophobicContact CB-CD1 4.47Å; V344-I423 HydrophobicContact CG1-CD1 4.14Å; V344-I423 HydrophobicContact CG1-CG1 3.99Å; V344-I423 HydrophobicContact CG1-CG2 4.2Å; V344-I423 HydrophobicContact CG2-CD1 4.47Å; I357-I423 HydrophobicContact CD1-CG2 3.95Å; E417-I423 HydrophobicContact CB-CD1 4.21Å; E417-I423 VanDerWaalsContact O-CD1 3.28Å; E417-I423 WeakPolarHBondContact O-CD1 3.42Å; W420-I423 HydrophobicContact CB-CB 4.31Å; W420-I423 HydrophobicContact CB-CD1 4.33Å; W420-I423 HydrophobicContact CB-CG1 4.34Å; W420-I423 HydrophobicContact CD2-CD1 4.36Å; W420-I423 HydrophobicContact CE3-CD1 3.9Å; W420-I423 PolarHBondContact O-N 3.19Å; I423-R425 VanDerWaalsContact C-N 3.3Å; I423-R425 PolarHBondContact O-N 3.06Å; I423-M426 CarbonylContact O-C 3.42Å; I423-M426 WeakPolarHBondContact O-CA 3.3Å; I423-M426 PolarHBondContact O-N 3.07Å; I423-T427 WeakPolarHBondContact O-CG2 3.02Å; I423-T427 PolarHBondContact O-N 2.77Å
424R96.8Very high97.7Very high86 Ų8623.2 Ų23.233%0.32512%0.116SC..Hα-helixtrans-50.3-51.4175.1-174.5-174.3173.6-156.2-3.9111.3Y55 T59 W420 S421 M426 T427 L428Y55-R424 HydrophobicContact CE2-CG 4.47Å; Y55-R424 WeakPolarHBondContact OH-CB 3.38Å; Y55-R424 VanDerWaalsContact OH-CD 3.3Å; Y55-R424 WeakPolarHBondContact OH-CD 3.03Å; Y55-R424 WeakPolarHBondContact OH-CG 3.32Å; T59-R424 HydrophobicContact CG2-CG 4.14Å; W420-R424 PolarHBondContact O-N 3.41Å; S421-R424 PolarHBondContact O-N 3.07Å; R424-M426 VanDerWaalsContact C-N 3.29Å; R424-M426 PolarHBondContact O-N 2.8Å; R424-T427 PolarHBondContact O-N 2.74Å; R424-T427 VanDerWaalsContact O-N 3.11Å; R424-T427 PolarHBondContact O-OG1 3.42Å; R424-L428 PolarHBondContact O-N 3.08Å
425R96.1Very high97.6Very high43 Ų4330.7 Ų30.716%0.16215%0.151CC..Hα-helixtrans-65-34.1-178.9-62.9-62.1-62.5179.811.8112.1S421 T422 I423 L428 F429 M484 E488S421-R425 WeakPolarHBondContact O-CG 3.46Å; S421-R425 PolarHBondContact O-N 2.87Å; T422-R425 PolarHBondContact O-N 2.67Å; I423-R425 VanDerWaalsContact C-N 3.3Å; I423-R425 PolarHBondContact O-N 3.06Å; R425-L428 WeakPolarHBondContact O-CB 3.47Å; R425-L428 PolarHBondContact O-N 2.9Å; R425-F429 PolarHBondContact O-N 3.45Å; R425-M484 HydrophobicContact CB-CB 4.48Å; R425-M484 WeakPolarHBondContact CB-O 3.16Å; R425-M484 VanDerWaalsContact CG-O 3.23Å; R425-M484 WeakPolarHBondContact CG-O 3.49Å; R425-E488 IonicContact CZ-OE2 2.93Å; R425-E488 IonicContact NH1-OE2 3.7Å; R425-E488 PolarHBondContact NH1-OE2 3.07Å
426M98.4Very high97.6Very high0 Ų033.2 Ų33.20%016%0.162CC..Hα-helixtrans-69.9-28.6173.7-72-54.6-55.300113.3F341 A345 L348 A349 T422 I423 R424 L428 F429 R430 F458 V485 A518F341-M426 HydrophobicContact CE2-CG 3.91Å; F341-M426 HydrophobicContact CZ-CG 4.23Å; A345-M426 HydrophobicContact CB-CE 4.3Å; A345-M426 HydrophobicContact CB-CG 3.97Å; A345-M426 HydrophobicContact CB-SD 4.4Å; A345-M426 WeakPolarHBondContact O-CE 3.4Å; L348-M426 HydrophobicContact CB-CB 4.23Å; L348-M426 HydrophobicContact CB-CE 4.48Å; L348-M426 HydrophobicContact CD1-CB 3.57Å; A349-M426 HydrophobicContact CB-CE 4.09Å; T422-M426 WeakPolarHBondContact O-CG 3.3Å; T422-M426 PolarHBondContact O-N 3.29Å; T422-M426 VanDerWaalsContact O-N 3.08Å; I423-M426 CarbonylContact O-C 3.42Å; I423-M426 WeakPolarHBondContact O-CA 3.3Å; I423-M426 PolarHBondContact O-N 3.07Å; R424-M426 VanDerWaalsContact C-N 3.29Å; R424-M426 PolarHBondContact O-N 2.8Å; M426-L428 VanDerWaalsContact C-N 3.34Å; M426-F429 HydrophobicContact CE-CB 4.17Å; M426-F429 HydrophobicContact CE-CD1 3.64Å; M426-F429 HydrophobicContact CE-CE1 4.34Å; M426-F429 HydrophobicContact CE-CG 4.08Å; M426-F429 PolarHBondContact O-N 2.94Å; M426-F429 HydrophobicContact SD-CB 4.32Å; M426-R430 WeakPolarHBondContact O-CB 3.41Å; M426-R430 PolarHBondContact O-N 3.3Å; M426-F458 HydrophobicContact CE-CD2 4Å; M426-F458 HydrophobicContact CE-CE2 3.89Å; M426-V485 HydrophobicContact SD-CG2 3.93Å; M426-A518 HydrophobicContact CE-CB 4.14Å; M426-A518 HydrophobicContact SD-CB 3.64Å
427T98.5Very high97.6Very high0 Ų036.8 Ų36.80%019%0.186CC..Hα-helixtrans-65.7-38.6170.372.80000111.6V36 G60 I61 L348 I357 I423 R424 R430 S431V36-T427 HydrophobicContact CG1-CG2 4.38Å; G60-T427 PolarHBondContact N-OG1 2.68Å; I61-T427 HydrophobicContact CD1-CG2 4.32Å; I61-T427 HydrophobicContact CG1-CG2 4.12Å; L348-T427 HydrophobicContact CD1-CG2 4.19Å; I357-T427 HydrophobicContact CD1-CG2 4.36Å; I423-T427 WeakPolarHBondContact O-CG2 3.02Å; I423-T427 PolarHBondContact O-N 2.77Å; R424-T427 PolarHBondContact O-N 2.74Å; R424-T427 VanDerWaalsContact O-N 3.11Å; R424-T427 PolarHBondContact O-OG1 3.42Å; T427-R430 WeakPolarHBondContact O-CB 3.32Å; T427-R430 PolarHBondContact O-N 3.13Å; T427-S431 PolarHBondContact O-N 2.65Å
428L98.1Very high97.6Very high43 Ų4338.9 Ų38.923%0.22520%0.198CC..Hα-helixtrans-66.9-40.5173.8-65.2171.8000111.2R424 R425 M426 R430 S431 E432 M484R424-L428 PolarHBondContact O-N 3.08Å; R425-L428 WeakPolarHBondContact O-CB 3.47Å; R425-L428 PolarHBondContact O-N 2.9Å; M426-L428 VanDerWaalsContact C-N 3.34Å; L428-R430 VanDerWaalsContact C-N 3.33Å; L428-R430 PolarHBondContact O-N 3.15Å; L428-S431 WeakPolarHBondContact O-CB 3.23Å; L428-S431 PolarHBondContact O-N 3.37Å; L428-E432 WeakPolarHBondContact O-CG 3.15Å; L428-E432 PolarHBondContact O-N 2.05Å; L428-M484 HydrophobicContact CB-CE 3.89Å
429F98.6Very high97.6Very high0 Ų041.3 Ų41.30%021%0.213CC..Hα-helixtrans-57.9-46.8172.7177.3-96.1000111.3A349 R425 M426 S431 E432 V433 F458 M484 A518 I519A349-F429 HydrophobicContact CB-CD1 4.31Å; A349-F429 HydrophobicContact CB-CE1 3.78Å; R425-F429 PolarHBondContact O-N 3.45Å; M426-F429 HydrophobicContact CE-CB 4.17Å; M426-F429 HydrophobicContact CE-CD1 3.64Å; M426-F429 HydrophobicContact CE-CE1 4.34Å; M426-F429 HydrophobicContact CE-CG 4.08Å; M426-F429 PolarHBondContact O-N 2.94Å; M426-F429 HydrophobicContact SD-CB 4.32Å; F429-S431 VanDerWaalsContact C-N 3.29Å; F429-S431 PolarHBondContact O-N 2.86Å; F429-E432 PolarHBondContact O-N 3.35Å; F429-V433 HydrophobicContact CD1-CG1 4.5Å; F429-V433 HydrophobicContact CD1-CG2 4.24Å; F429-V433 HydrophobicContact CD2-CG1 4.36Å; F429-V433 HydrophobicContact CE1-CG1 4.07Å; F429-V433 HydrophobicContact CE1-CG2 4.01Å; F429-V433 HydrophobicContact CE2-CG1 3.92Å; F429-V433 HydrophobicContact CZ-CG1 3.77Å; F429-V433 WeakPolarHBondContact O-CG1 3.07Å; F429-V433 VanDerWaalsContact O-CG2 3.3Å; F429-V433 WeakPolarHBondContact O-CG2 3.45Å; F429-V433 PolarHBondContact O-N 3.48Å; F429-V433 VanDerWaalsContact O-N 3.1Å; F429-F458 HydrophobicContact CE1-CB 4.38Å; F429-F458 HydrophobicContact CZ-CB 4.11Å; F429-M484 HydrophobicContact CB-CE 4.11Å; F429-M484 HydrophobicContact CB-SD 4.01Å; F429-M484 HydrophobicContact CD2-SD 3.94Å; F429-M484 HydrophobicContact CG-SD 4.49Å; F429-A518 HydrophobicContact CD2-CB 3.77Å; F429-A518 HydrophobicContact CE2-CB 3.98Å; F429-A518 HydrophobicContact CG-CB 4.05Å; F429-A518 HydrophobicContact CZ-CB 4.45Å; F429-I519 WeakPolarHBondContact CE2-O 3.4Å
430R98.5Very high97.6Very high24 Ų2443.7 Ų43.79%0.09123%0.227CC..Hα-helixtrans-56.5-43.7177.1-174.3-81.7-166.5-16.811.2111.6S35 V36 L348 P355 M426 T427 L428 V433 A434S35-R430 VanDerWaalsContact CB-NH2 3.27Å; S35-R430 PolarHBondContact O-NH2 3.21Å; S35-R430 PolarHBondContact OG-NE 3.05Å; S35-R430 PolarHBondContact OG-NH2 2.99Å; V36-R430 HydrophobicContact CG2-CB 4.3Å; V36-R430 HydrophobicContact CG2-CG 3.87Å; L348-R430 HydrophobicContact CB-CB 4.36Å; L348-R430 HydrophobicContact CD2-CG 4.4Å; L348-R430 WeakPolarHBondContact O-CB 3.42Å; L348-R430 WeakPolarHBondContact O-CG 3.36Å; P355-R430 VanDerWaalsContact CD-CZ 3.44Å; P355-R430 VanDerWaalsContact CD-NH1 3.29Å; M426-R430 WeakPolarHBondContact O-CB 3.41Å; M426-R430 PolarHBondContact O-N 3.3Å; T427-R430 WeakPolarHBondContact O-CB 3.32Å; T427-R430 PolarHBondContact O-N 3.13Å; L428-R430 VanDerWaalsContact C-N 3.33Å; L428-R430 PolarHBondContact O-N 3.15Å; R430-V433 PolarHBondContact O-N 3Å; R430-A434 PolarHBondContact O-N 2.9Å
431S98.3Very high97.6Very high23 Ų2345.2 Ų45.216%0.16124%0.237CC..Hα-helixtrans-58.6-51.6175.9-176.20000111.6D33 T427 L428 F429 V433 A434D33-S431 VanDerWaalsContact O-CA 3.24Å; D33-S431 WeakPolarHBondContact O-CA 3.11Å; D33-S431 WeakPolarHBondContact O-CB 3.3Å; D33-S431 PolarHBondContact O-OG 3.14Å; T427-S431 PolarHBondContact O-N 2.65Å; L428-S431 WeakPolarHBondContact O-CB 3.23Å; L428-S431 PolarHBondContact O-N 3.37Å; F429-S431 VanDerWaalsContact C-N 3.29Å; F429-S431 PolarHBondContact O-N 2.86Å; S431-V433 PolarHBondContact O-N 3.38Å; S431-A434 VanDerWaalsContact O-CB 3.27Å; S431-A434 WeakPolarHBondContact O-CB 3.48Å; S431-A434 PolarHBondContact O-N 3Å; S431-A434 VanDerWaalsContact O-N 3.16Å
432E98.3Very high97.8Very high72 Ų7244.7 Ų44.734%0.33623%0.23SC..Hα-helixtrans-60.8-31.6179.8-70.4-69.313900113.9L428 F429 S455 T521 A522L428-E432 WeakPolarHBondContact O-CG 3.15Å; L428-E432 PolarHBondContact O-N 2.05Å; F429-E432 PolarHBondContact O-N 3.35Å; E432-S455 WeakPolarHBondContact O-CB 3.37Å; E432-T521 PolarHBondContact OE2-OG1 3.19Å; E432-A522 HydrophobicContact CG-CB 3.86Å; E432-A522 WeakPolarHBondContact OE1-CB 3.24Å; E432-A522 VanDerWaalsContact OE2-CB 3.25Å; E432-A522 WeakPolarHBondContact OE2-CB 3.5Å; E432-A522 PolarHBondContact OE2-N 2.96Å
433V98.5Very high97.9Very high0 Ų045.4 Ų45.40%023%0.234CC..THydrogen-bonded Turntrans-99.412.2-177.5-55.20000113.5F429 R430 S431 E435 Q436 R452F429-V433 HydrophobicContact CD1-CG1 4.5Å; F429-V433 HydrophobicContact CD1-CG2 4.24Å; F429-V433 HydrophobicContact CD2-CG1 4.36Å; F429-V433 HydrophobicContact CE1-CG1 4.07Å; F429-V433 HydrophobicContact CE1-CG2 4.01Å; F429-V433 HydrophobicContact CE2-CG1 3.92Å; F429-V433 HydrophobicContact CZ-CG1 3.77Å; F429-V433 WeakPolarHBondContact O-CG1 3.07Å; F429-V433 VanDerWaalsContact O-CG2 3.3Å; F429-V433 WeakPolarHBondContact O-CG2 3.45Å; F429-V433 PolarHBondContact O-N 3.48Å; F429-V433 VanDerWaalsContact O-N 3.1Å; R430-V433 PolarHBondContact O-N 3Å; S431-V433 PolarHBondContact O-N 3.38Å; V433-E435 PolarHBondContact O-N 3.2Å; V433-Q436 WeakPolarHBondContact O-CB 3.49Å; V433-Q436 PolarHBondContact O-N 3.48Å; V433-Q436 VanDerWaalsContact O-N 3.16Å; V433-R452 HydrophobicContact CB-CB 3.57Å; V433-R452 HydrophobicContact CB-CG 3.99Å; V433-R452 HydrophobicContact CG1-CB 3.71Å; V433-R452 HydrophobicContact CG1-CG 4.23Å; V433-R452 HydrophobicContact CG2-CB 4.18Å; V433-R452 HydrophobicContact CG2-CG 4.04Å; V433-R452 PolarHBondContact O-NH2 2.92Å
434A97.8Very high97.9Very high19 Ų1947.3 Ų47.316%0.15724%0.243CC..THydrogen-bonded Turntrans-52.3140.1178.900000111.7D33 R430 S431 Q436D33-A434 HydrophobicContact CB-CB 4.04Å; R430-A434 PolarHBondContact O-N 2.9Å; S431-A434 VanDerWaalsContact O-CB 3.27Å; S431-A434 WeakPolarHBondContact O-CB 3.48Å; S431-A434 PolarHBondContact O-N 3Å; S431-A434 VanDerWaalsContact O-N 3.16Å; A434-Q436 PolarHBondContact O-N 3.2Å
435E95.5Very high97.9Very high157 Ų15747.3 Ų47.373%0.73425%0.249SC*.THydrogen-bonded Turntrans606.3179-53.3178.215700115.4S32 V433S32-E435 WeakPolarHBondContact CB-OE1 3.14Å; S32-E435 VanDerWaalsContact OG-CD 3.23Å; S32-E435 PolarHBondContact OG-OE1 3.32Å; V433-E435 PolarHBondContact O-N 3.2Å
436Q98.1Very high98Very high58 Ų5846.1 Ų46.127%0.27125%0.246SC..PPolyproline II helixtrans-86.7136.9177.9-60.8-54.2-63.600112.2V433 A434 R452 S455V433-Q436 WeakPolarHBondContact O-CB 3.49Å; V433-Q436 PolarHBondContact O-N 3.48Å; V433-Q436 VanDerWaalsContact O-N 3.16Å; A434-Q436 PolarHBondContact O-N 3.2Å; Q436-R452 HydrophobicContact CB-CB 4.08Å; Q436-R452 WeakPolarHBondContact CB-O 3.23Å; Q436-R452 VanDerWaalsContact O-CZ 3.3Å; Q436-R452 PolarHBondContact O-NE 2.96Å; Q436-R452 PolarHBondContact O-NH2 3.38Å; Q436-S455 WeakPolarHBondContact CG-OG 3.36Å
437P97.5Very high98Very high75 Ų7547.2 Ų47.249%0.48725%0.25SS..PPolyproline II helixtrans-74.6162.3176.232.6-36.2000111.9T439 R452 G453P437-T439 HydrophobicContact CG-CG2 4.3Å; P437-R452 CarbonylContact O-C 3.52Å; P437-R452 WeakPolarHBondContact O-CA 3.2Å; P437-G453 PolarHBondContact O-N 3.47Å
438V98.5Very high98Very high45 Ų4547.2 Ų47.227%0.27325%0.25SS..EExtended strand (participates in β ladder)trans-74.2125.5167.1179.10000109.3W350 P351 M441 F450 S451W350-V438 HydrophobicContact CE3-CG2 4.1Å; W350-V438 HydrophobicContact CH2-CG1 4.27Å; W350-V438 HydrophobicContact CH2-CG2 4.02Å; W350-V438 HydrophobicContact CZ3-CG1 4.01Å; W350-V438 HydrophobicContact CZ3-CG2 3.75Å; P351-V438 HydrophobicContact CG-CG2 3.56Å; V438-M441 HydrophobicContact CG1-CB 4.35Å; V438-M441 HydrophobicContact CG1-SD 4.36Å; V438-F450 HydrophobicContact CG1-CB 3.75Å; V438-F450 HydrophobicContact CG1-CD2 4.22Å; V438-F450 HydrophobicContact CG1-CG 4.06Å; V438-F450 HydrophobicContact CG2-CD2 4.43Å; V438-S451 WeakPolarHBondContact CA-O 3.19Å
439T98.4Very high98Very high51 Ų5145.2 Ų45.231%0.31324%0.239SC..EExtended strand (participates in β ladder)trans-134.7168.6173.166.20000110.8P437 M441 S451P437-T439 HydrophobicContact CG-CG2 4.3Å; T439-M441 PolarHBondContact O-N 3.42Å; T439-M441 VanDerWaalsContact O-N 3.08Å; T439-S451 PolarHBondContact N-O 2.71Å; T439-S451 PolarHBondContact O-N 2.69Å; T439-S451 WeakPolarHBondContact OG1-CB 3.4Å
440D97.8Very high98Very high68 Ų6845.2 Ų45.236%0.36424%0.239SC..EExtended strand (participates in β ladder)trans53.934.5172.4-49.6-68.5000114.2S451 Q473D440-S451 PolarHBondContact OD2-OG 2.71Å; D440-Q473 HydrophobicContact CB-CB 4.16Å; D440-Q473 HydrophobicContact CB-CG 4.25Å; D440-Q473 WeakPolarHBondContact OD1-CG 3.5Å
441M98.2Very high98Very high82 Ų8244 Ų4440%0.40424%0.235SC..EExtended strand (participates in β ladder)trans-75.1137.8-174-176.8175.263.800111.9G298 W350 V438 T439 T443 I448 A449 F450G298-M441 WeakPolarHBondContact CA-SD 3.42Å; W350-M441 HydrophobicContact CH2-SD 4.41Å; V438-M441 HydrophobicContact CG1-CB 4.35Å; V438-M441 HydrophobicContact CG1-SD 4.36Å; T439-M441 PolarHBondContact O-N 3.42Å; T439-M441 VanDerWaalsContact O-N 3.08Å; M441-T443 HydrophobicContact CG-CG2 4.45Å; M441-I448 HydrophobicContact SD-CD1 4.26Å; M441-A449 CarbonylContact C-O 3.33Å; M441-A449 VanDerWaalsContact CA-O 3.32Å; M441-A449 WeakPolarHBondContact CA-O 3.46Å; M441-F450 HydrophobicContact CB-CB 4.08Å; M441-F450 HydrophobicContact CG-CB 4.19Å
442I98.1Very high98Very high51 Ų5143.4 Ų43.426%0.26223%0.229SC..EExtended strand (participates in β ladder)trans-130.1136.8169.1-176.6172.1000109.6I448 A449 W468 V472I442-I448 WeakPolarHBondContact O-CA 3.49Å; I442-A449 HydrophobicContact CG2-CB 3.86Å; I442-A449 PolarHBondContact N-O 2.88Å; I442-A449 PolarHBondContact O-N 3.45Å; I442-W468 HydrophobicContact CG1-CZ2 4.49Å; I442-W468 HydrophobicContact CG2-CH2 4.02Å; I442-W468 HydrophobicContact CG2-CZ2 4.13Å; I442-V472 HydrophobicContact CD1-CG1 4.45Å; I442-V472 HydrophobicContact CG2-CG1 3.95Å
443T98Very high98Very high56 Ų5640.4 Ų40.434%0.34422%0.217SC..EExtended strand (participates in β ladder)trans-126.5140.6175.751.50000110.7M295 M441 R447 I448M295-T443 WeakPolarHBondContact O-CB 3.47Å; M295-T443 PolarHBondContact O-OG1 3.02Å; M441-T443 HydrophobicContact CG-CG2 4.45Å; T443-R447 WeakPolarHBondContact CA-O 3.43Å; T443-I448 HydrophobicContact CG2-CB 4.26Å; T443-I448 HydrophobicContact CG2-CD1 3.86Å; T443-I448 HydrophobicContact CG2-CG1 3.82Å
444E97.3Very high98Very high40 Ų4050.2 Ų50.219%0.18725%0.254CS..EExtended strand (participates in β ladder)trans-141.6174.7172.1-69.3-179-153.300108.6M295 N446 R447 W468 R470M295-E444 VanDerWaalsContact CB-O 3.23Å; M295-E444 WeakPolarHBondContact CB-O 3.45Å; E444-N446 PolarHBondContact O-N 3.01Å; E444-R447 HydrophobicContact CB-CB 4.06Å; E444-R447 PolarHBondContact N-O 3.45Å; E444-R447 PolarHBondContact O-N 2.89Å; E444-R447 IonicContact OE2-NH1 2.78Å; E444-W468 VanDerWaalsContact CD-NE1 3.32Å; E444-W468 HydrophobicContact CG-CZ2 4.43Å; E444-W468 PolarHBondContact OE1-NE1 2.7Å; E444-W468 PolarHBondContact OE2-NE1 2.77Å; E444-R470 IonicContact OE1-CZ 2.71Å; E444-R470 IonicContact OE1-NE 3.78Å; E444-R470 PolarHBondContact OE1-NE 3.49Å; E444-R470 IonicContact OE1-NH2 2.93Å; E444-R470 PolarHBondContact OE1-NH2 3.29Å; E444-R470 IonicContact OE2-CZ 3.83Å; E444-R470 IonicContact OE2-NE 3.08Å; E444-R470 IonicContact OE2-NH2 2.74Å; E444-R470 PolarHBondContact OE2-NH2 3.42Å
445D97.5Very high98Very high86 Ų8650.4 Ų50.446%0.4625%0.254SS..THydrogen-bonded Turntrans-49.7116.3176-178.128.5000111.6N293 R447N293-D445 PolarHBondContact ND2-OD1 2.93Å; D445-R447 PolarHBondContact O-N 3.16Å
446N97.9Very high98.2Very high18 Ų1842.9 Ų42.910%0.09622%0.219CC..THydrogen-bonded Turntrans5428.5-176.5-75-81.6000115.1H290 N293 E444 N462 D463H290-N446 PolarHBondContact ND1-OD1 3.07Å; N293-N446 WeakPolarHBondContact OD1-CA 3.34Å; N293-N446 PolarHBondContact OD1-N 3.35Å; E444-N446 PolarHBondContact O-N 3.01Å; N446-N462 HydrophobicContact CB-CB 4.26Å; N446-N462 WeakPolarHBondContact O-CA 3.17Å; N446-N462 WeakPolarHBondContact O-CB 3.48Å; N446-N462 PolarHBondContact O-N 2.82Å; N446-D463 PolarHBondContact O-N 2.75Å
447R98.1Very high98.2Very high24 Ų2440.2 Ų40.29%0.09121%0.207CC..EExtended strand (participates in β ladder)trans-139.9142.1-175.7-73.4160.3-178.3150.113111.7T443 E444 D445 L460 N461 D463 Y466 W468T443-R447 WeakPolarHBondContact CA-O 3.43Å; E444-R447 HydrophobicContact CB-CB 4.06Å; E444-R447 PolarHBondContact N-O 3.45Å; E444-R447 PolarHBondContact O-N 2.89Å; E444-R447 IonicContact OE2-NH1 2.78Å; D445-R447 PolarHBondContact O-N 3.16Å; R447-L460 WeakPolarHBondContact CA-O 3.48Å; R447-N461 HydrophobicContact CG-CB 4.32Å; R447-N461 WeakPolarHBondContact CG-OD1 3.42Å; R447-N461 PolarHBondContact NE-OD1 2.88Å; R447-D463 IonicContact CZ-OD2 2.78Å; R447-D463 VanDerWaalsContact NH2-CB 3.34Å; R447-D463 IonicContact NH2-OD2 2.68Å; R447-D463 PolarHBondContact NH2-OD2 3.28Å; R447-Y466 PolarHBondContact NH2-O 2.85Å; R447-Y466 VanDerWaalsContact NH2-O 3.14Å; R447-W468 HydrophobicContact CB-CD2 4.04Å; R447-W468 HydrophobicContact CB-CE3 3.92Å; R447-W468 HydrophobicContact CB-CH2 3.91Å; R447-W468 HydrophobicContact CB-CZ2 4.01Å; R447-W468 HydrophobicContact CB-CZ3 3.85Å; R447-W468 HydrophobicContact CG-CD2 3.91Å; R447-W468 HydrophobicContact CG-CE3 3.95Å; R447-W468 HydrophobicContact CG-CG 4.23Å; R447-W468 HydrophobicContact CG-CZ3 4.39Å
448I98.7Very high98.3Very high0 Ų036.6 Ų36.60%018%0.184CC..EExtended strand (participates in β ladder)trans-150.1138.6174.2-174.3164.3000109.9F294 F346 M441 I442 T443 F450 L460F294-I448 HydrophobicContact CB-CG2 4.26Å; F294-I448 HydrophobicContact CD1-CG2 4.03Å; F294-I448 HydrophobicContact CG-CG2 4.44Å; F346-I448 HydrophobicContact CD2-CG2 4.33Å; F346-I448 HydrophobicContact CE2-CD1 4.29Å; F346-I448 HydrophobicContact CE2-CG2 3.98Å; M441-I448 HydrophobicContact SD-CD1 4.26Å; I442-I448 WeakPolarHBondContact O-CA 3.49Å; T443-I448 HydrophobicContact CG2-CB 4.26Å; T443-I448 HydrophobicContact CG2-CD1 3.86Å; T443-I448 HydrophobicContact CG2-CG1 3.82Å; I448-F450 HydrophobicContact CD1-CD1 4.32Å; I448-F450 HydrophobicContact CG1-CD1 4.05Å; I448-F450 HydrophobicContact CG1-CE1 4.47Å; I448-L460 HydrophobicContact CG2-CB 4.15Å; I448-L460 HydrophobicContact CG2-CD2 4.42Å; I448-L460 PolarHBondContact N-O 2.67Å; I448-L460 VanDerWaalsContact N-O 3.08Å; I448-L460 PolarHBondContact O-N 3.36Å
449A98.7Very high98.3Very high0 Ų034.5 Ų34.50%017%0.171CC..EExtended strand (participates in β ladder)trans-140.9146.6169.100000110M441 I442 F457 F458 A459 W468 L509M441-A449 CarbonylContact C-O 3.33Å; M441-A449 VanDerWaalsContact CA-O 3.32Å; M441-A449 WeakPolarHBondContact CA-O 3.46Å; I442-A449 HydrophobicContact CG2-CB 3.86Å; I442-A449 PolarHBondContact N-O 2.88Å; I442-A449 PolarHBondContact O-N 3.45Å; A449-F457 HydrophobicContact CB-CE2 4.17Å; A449-F457 HydrophobicContact CB-CZ 3.76Å; A449-F458 CarbonylContact C-O 3.54Å; A449-F458 WeakPolarHBondContact CA-O 3.42Å; A449-F458 WeakPolarHBondContact CB-O 3.1Å; A449-A459 HydrophobicContact CB-CB 3.7Å; A449-W468 HydrophobicContact CB-CH2 3.72Å; A449-W468 HydrophobicContact CB-CZ3 3.85Å; A449-L509 HydrophobicContact CB-CD2 4.27Å
450F98.8Very high98.3Very high0 Ų032 Ų320%016%0.156CC..EExtended strand (participates in β ladder)trans-158.5155.5-179.554.5-93.3000111.5F346 A349 W350 V438 M441 I448 R452 F457 F458F346-F450 HydrophobicContact CE2-CE1 4.21Å; A349-F450 HydrophobicContact CB-CE2 4.33Å; A349-F450 HydrophobicContact CB-CZ 3.97Å; A349-F450 WeakPolarHBondContact O-CE2 3.44Å; W350-F450 HydrophobicContact CE3-CD1 4.23Å; W350-F450 AromaticContact CE3-CE1 3.72Å; W350-F450 HydrophobicContact CE3-CE1 3.72Å; W350-F450 HydrophobicContact CE3-CE2 4.23Å; W350-F450 AromaticContact CE3-CZ 3.72Å; W350-F450 HydrophobicContact CE3-CZ 3.72Å; W350-F450 HydrophobicContact CZ3-CD1 4.06Å; W350-F450 HydrophobicContact CZ3-CE1 4.01Å; W350-F450 HydrophobicContact CZ3-CG 4.44Å; W350-F450 HydrophobicContact CZ3-CZ 4.34Å; V438-F450 HydrophobicContact CG1-CB 3.75Å; V438-F450 HydrophobicContact CG1-CD2 4.22Å; V438-F450 HydrophobicContact CG1-CG 4.06Å; V438-F450 HydrophobicContact CG2-CD2 4.43Å; M441-F450 HydrophobicContact CB-CB 4.08Å; M441-F450 HydrophobicContact CG-CB 4.19Å; I448-F450 HydrophobicContact CD1-CD1 4.32Å; I448-F450 HydrophobicContact CG1-CD1 4.05Å; I448-F450 HydrophobicContact CG1-CE1 4.47Å; F450-R452 HydrophobicContact CD2-CG 4.26Å; F450-R452 HydrophobicContact CE2-CG 4.06Å; F450-F457 VanDerWaalsContact O-CD2 3.32Å; F450-F457 WeakPolarHBondContact O-CD2 3.43Å; F450-F458 HydrophobicContact CD1-CD1 4.4Å; F450-F458 HydrophobicContact CD2-CB 4.45Å; F450-F458 HydrophobicContact CE1-CB 4.49Å; F450-F458 AromaticContact CE1-CD1 3.58Å; F450-F458 HydrophobicContact CE1-CD1 3.58Å; F450-F458 HydrophobicContact CE1-CE1 4.25Å; F450-F458 HydrophobicContact CE1-CG 4.4Å; F450-F458 HydrophobicContact CE2-CB 3.95Å; F450-F458 HydrophobicContact CE2-CD1 4.4Å; F450-F458 HydrophobicContact CE2-CG 4.48Å; F450-F458 HydrophobicContact CZ-CB 3.97Å; F450-F458 AromaticContact CZ-CD1 3.57Å; F450-F458 HydrophobicContact CZ-CD1 3.57Å; F450-F458 HydrophobicContact CZ-CE1 4.35Å; F450-F458 HydrophobicContact CZ-CG 4.01Å; F450-F458 PolarHBondContact N-O 3.13Å; F450-F458 PolarHBondContact O-N 3.49Å
451S98.8Very high98.2Very high0 Ų028.8 Ų28.80%014%0.138CC..EExtended strand (participates in β ladder)trans-87.4150.3166.5-60.60000110.6V438 T439 D440 G456 T474 G475V438-S451 WeakPolarHBondContact CA-O 3.19Å; T439-S451 PolarHBondContact N-O 2.71Å; T439-S451 PolarHBondContact O-N 2.69Å; T439-S451 WeakPolarHBondContact OG1-CB 3.4Å; D440-S451 PolarHBondContact OD2-OG 2.71Å; S451-G456 CarbonylContact C-O 3.04Å; S451-G456 WeakPolarHBondContact CA-O 3.45Å; S451-T474 VanDerWaalsContact OG-CA 3.28Å; S451-T474 WeakPolarHBondContact OG-CA 3.46Å; S451-G475 PolarHBondContact OG-N 3.21Å
452R98.5Very high98.2Very high10 Ų1024.9 Ų24.94%0.03812%0.119CC..EExtended strand (participates in β ladder)trans-105.586.2163-67.6-64.8-59-75.6-10.2107.8A349 V433 Q436 P437 F450 R454 S455 G456A349-R452 WeakPolarHBondContact O-CD 3.22Å; A349-R452 PolarHBondContact O-NH1 3.28Å; V433-R452 HydrophobicContact CB-CB 3.57Å; V433-R452 HydrophobicContact CB-CG 3.99Å; V433-R452 HydrophobicContact CG1-CB 3.71Å; V433-R452 HydrophobicContact CG1-CG 4.23Å; V433-R452 HydrophobicContact CG2-CB 4.18Å; V433-R452 HydrophobicContact CG2-CG 4.04Å; V433-R452 PolarHBondContact O-NH2 2.92Å; Q436-R452 HydrophobicContact CB-CB 4.08Å; Q436-R452 WeakPolarHBondContact CB-O 3.23Å; Q436-R452 VanDerWaalsContact O-CZ 3.3Å; Q436-R452 PolarHBondContact O-NE 2.96Å; Q436-R452 PolarHBondContact O-NH2 3.38Å; P437-R452 CarbonylContact O-C 3.52Å; P437-R452 WeakPolarHBondContact O-CA 3.2Å; F450-R452 HydrophobicContact CD2-CG 4.26Å; F450-R452 HydrophobicContact CE2-CG 4.06Å; R452-R454 PolarHBondContact O-N 3.18Å; R452-S455 PolarHBondContact O-N 3.39Å; R452-S455 VanDerWaalsContact O-N 3.08Å; R452-G456 PolarHBondContact N-O 3.38Å; R452-G456 PolarHBondContact O-N 2.81Å
453G97.9Very high98Very high8 Ų823.4 Ų23.48%0.08211%0.112CC..THydrogen-bonded Turntrans49.3-129.9-172.700000111.5P437 G475P437-G453 PolarHBondContact O-N 3.47Å; G453-G475 WeakPolarHBondContact O-CA 3.39Å
454R98Very high97.6Very high206 Ų20622.4 Ų22.478%0.77711%0.113SC*.THydrogen-bonded Turntrans-97.83.9176.8-63.1-174.7173.4176.8-1113.9R452 G475R452-R454 PolarHBondContact O-N 3.18Å; R454-G475 WeakPolarHBondContact CA-O 3.32Å; R454-G475 WeakPolarHBondContact CG-O 3.45Å
455S98.3Very high97.1Very high23 Ų2326.4 Ų26.416%0.16113%0.129CC..THydrogen-bonded Turntrans-98-28-171.4-53.90000113.2E432 Q436 R452 S520 T521E432-S455 WeakPolarHBondContact O-CB 3.37Å; Q436-S455 WeakPolarHBondContact CG-OG 3.36Å; R452-S455 PolarHBondContact O-N 3.39Å; R452-S455 VanDerWaalsContact O-N 3.08Å; S455-S520 CarbonylContact O-C 3.52Å; S455-S520 WeakPolarHBondContact O-CA 3.44Å; S455-S520 WeakPolarHBondContact O-CB 3.35Å; S455-T521 PolarHBondContact O-N 3.1Å; S455-T521 PolarHBondContact O-OG1 2.91Å
456G98.6Very high96.7Very high0 Ų026.4 Ų26.40%012%0.124CC..EExtended strand (participates in β ladder)trans-159.6169.1-179.800000115.1S451 R452 I519S451-G456 CarbonylContact C-O 3.04Å; S451-G456 WeakPolarHBondContact CA-O 3.45Å; R452-G456 PolarHBondContact N-O 3.38Å; R452-G456 PolarHBondContact O-N 2.81Å; G456-I519 CarbonylContact C-O 3.59Å; G456-I519 WeakPolarHBondContact CA-O 3.3Å
457F98.8Very high96.3Very high1 Ų126.7 Ų26.70%0.00413%0.127CC..EExtended strand (participates in β ladder)trans-140.6135.7175.7175-97.5000109.3A449 F450 A459 V472 T474 L476 A518 I519A449-F457 HydrophobicContact CB-CE2 4.17Å; A449-F457 HydrophobicContact CB-CZ 3.76Å; F450-F457 VanDerWaalsContact O-CD2 3.32Å; F450-F457 WeakPolarHBondContact O-CD2 3.43Å; F457-A459 HydrophobicContact CE1-CB 4.01Å; F457-A459 HydrophobicContact CZ-CB 4.3Å; F457-V472 HydrophobicContact CE1-CG2 4.33Å; F457-V472 HydrophobicContact CE2-CG2 4.14Å; F457-V472 HydrophobicContact CZ-CG2 3.56Å; F457-T474 HydrophobicContact CB-CG2 4.22Å; F457-T474 HydrophobicContact CD1-CG2 4.19Å; F457-T474 HydrophobicContact CD2-CG2 3.57Å; F457-T474 HydrophobicContact CE1-CG2 4.49Å; F457-T474 HydrophobicContact CE2-CG2 3.91Å; F457-T474 HydrophobicContact CG-CG2 3.72Å; F457-T474 HydrophobicContact CZ-CG2 4.36Å; F457-L476 HydrophobicContact CB-CD1 3.89Å; F457-A518 WeakPolarHBondContact O-CA 3.5Å; F457-I519 HydrophobicContact CB-CD1 4.43Å; F457-I519 HydrophobicContact CB-CG1 3.94Å; F457-I519 HydrophobicContact CD1-CD1 4.46Å; F457-I519 HydrophobicContact CD1-CG1 4.23Å; F457-I519 PolarHBondContact N-O 2.79Å; F457-I519 PolarHBondContact O-N 3.12Å
458F98.8Very high96Very high0 Ų025.5 Ų25.50%012%0.123CC..EExtended strand (participates in β ladder)trans-126.8140.2-178.6178.2-92.1000110A345 F346 A349 M426 F429 A449 F450 L460 V516 A518A345-F458 HydrophobicContact CB-CE2 4.17Å; A345-F458 HydrophobicContact CB-CZ 4.44Å; F346-F458 HydrophobicContact CB-CZ 4.38Å; F346-F458 HydrophobicContact CD2-CE1 4.07Å; A349-F458 HydrophobicContact CB-CB 3.97Å; A349-F458 HydrophobicContact CB-CD1 4Å; A349-F458 HydrophobicContact CB-CD2 3.29Å; A349-F458 HydrophobicContact CB-CE1 4.3Å; A349-F458 HydrophobicContact CB-CE2 3.63Å; A349-F458 HydrophobicContact CB-CG 3.48Å; A349-F458 VanDerWaalsContact CB-CG 3.48Å; A349-F458 HydrophobicContact CB-CZ 4.12Å; M426-F458 HydrophobicContact CE-CD2 4Å; M426-F458 HydrophobicContact CE-CE2 3.89Å; F429-F458 HydrophobicContact CE1-CB 4.38Å; F429-F458 HydrophobicContact CZ-CB 4.11Å; A449-F458 CarbonylContact C-O 3.54Å; A449-F458 WeakPolarHBondContact CA-O 3.42Å; A449-F458 WeakPolarHBondContact CB-O 3.1Å; F450-F458 HydrophobicContact CD1-CD1 4.4Å; F450-F458 HydrophobicContact CD2-CB 4.45Å; F450-F458 HydrophobicContact CE1-CB 4.49Å; F450-F458 AromaticContact CE1-CD1 3.58Å; F450-F458 HydrophobicContact CE1-CD1 3.58Å; F450-F458 HydrophobicContact CE1-CE1 4.25Å; F450-F458 HydrophobicContact CE1-CG 4.4Å; F450-F458 HydrophobicContact CE2-CB 3.95Å; F450-F458 HydrophobicContact CE2-CD1 4.4Å; F450-F458 HydrophobicContact CE2-CG 4.48Å; F450-F458 HydrophobicContact CZ-CB 3.97Å; F450-F458 AromaticContact CZ-CD1 3.57Å; F450-F458 HydrophobicContact CZ-CD1 3.57Å; F450-F458 HydrophobicContact CZ-CE1 4.35Å; F450-F458 HydrophobicContact CZ-CG 4.01Å; F450-F458 PolarHBondContact N-O 3.13Å; F450-F458 PolarHBondContact O-N 3.49Å; F458-L460 HydrophobicContact CE1-CB 3.7Å; F458-L460 HydrophobicContact CE1-CD1 4.31Å; F458-L460 HydrophobicContact CZ-CB 4.09Å; F458-L460 HydrophobicContact CZ-CD1 4.27Å; F458-V516 HydrophobicContact CD2-CG1 4.12Å; F458-V516 HydrophobicContact CE2-CG1 3.26Å; F458-V516 HydrophobicContact CZ-CG1 3.52Å; F458-A518 HydrophobicContact CD2-CB 4.21Å
459A98.6Very high95.6Very high0 Ų028.1 Ų28.10%014%0.137CC..EExtended strand (participates in β ladder)trans-140.2139.7173.200000111.2A449 F457 L509 L511 V516 M517A449-A459 HydrophobicContact CB-CB 3.7Å; F457-A459 HydrophobicContact CE1-CB 4.01Å; F457-A459 HydrophobicContact CZ-CB 4.3Å; A459-L509 HydrophobicContact CB-CD1 3.8Å; A459-L509 HydrophobicContact CB-CD2 3.83Å; A459-L509 HydrophobicContact CB-CG 4.49Å; A459-L511 HydrophobicContact CB-CD2 3.96Å; A459-L511 WeakPolarHBondContact O-CD2 3.33Å; A459-V516 CarbonylContact O-C 3.42Å; A459-V516 WeakPolarHBondContact O-CA 3.46Å; A459-M517 PolarHBondContact N-O 3.2Å; A459-M517 PolarHBondContact O-N 2.71Å
460L98.3Very high95.4Very high0 Ų033 Ų330%016%0.155CC..EExtended strand (participates in β ladder)trans-132.4125.7179.4177.4161000109F294 M342 F346 R447 I448 F458 N462 V516F294-L460 HydrophobicContact CD1-CD2 4.16Å; F294-L460 HydrophobicContact CD2-CD2 3.71Å; F294-L460 HydrophobicContact CE1-CD1 3.95Å; F294-L460 HydrophobicContact CE1-CD2 4.23Å; F294-L460 HydrophobicContact CE2-CD1 4.41Å; F294-L460 HydrophobicContact CE2-CD2 3.79Å; F294-L460 HydrophobicContact CG-CD2 3.9Å; F294-L460 HydrophobicContact CZ-CD1 3.89Å; F294-L460 HydrophobicContact CZ-CD2 4.05Å; M342-L460 HydrophobicContact CG-CD1 3.48Å; M342-L460 VanDerWaalsContact CG-CD1 3.48Å; M342-L460 HydrophobicContact CG-CD2 4.49Å; M342-L460 HydrophobicContact CG-CG 3.9Å; M342-L460 HydrophobicContact SD-CD1 4.06Å; M342-L460 HydrophobicContact SD-CD2 4.01Å; M342-L460 HydrophobicContact SD-CG 4Å; F346-L460 HydrophobicContact CB-CD1 4.1Å; F346-L460 HydrophobicContact CD2-CD1 4.16Å; R447-L460 WeakPolarHBondContact CA-O 3.48Å; I448-L460 HydrophobicContact CG2-CB 4.15Å; I448-L460 HydrophobicContact CG2-CD2 4.42Å; I448-L460 PolarHBondContact N-O 2.67Å; I448-L460 VanDerWaalsContact N-O 3.08Å; I448-L460 PolarHBondContact O-N 3.36Å; F458-L460 HydrophobicContact CE1-CB 3.7Å; F458-L460 HydrophobicContact CE1-CD1 4.31Å; F458-L460 HydrophobicContact CZ-CB 4.09Å; F458-L460 HydrophobicContact CZ-CD1 4.27Å; L460-N462 HydrophobicContact CD2-CB 3.79Å; L460-V516 HydrophobicContact CB-CG2 4.37Å; L460-V516 HydrophobicContact CD1-CG2 4.33Å; L460-V516 HydrophobicContact CG-CG2 4.13Å
461N96.9Very high95.3Very high0 Ų037.1 Ų37.10%018%0.18CC..EExtended strand (participates in β ladder)trans-115.397171.7-179.324.1000109R447 D463 Y466 W468 L511 R512 S513 R514 K515R447-N461 HydrophobicContact CG-CB 4.32Å; R447-N461 WeakPolarHBondContact CG-OD1 3.42Å; R447-N461 PolarHBondContact NE-OD1 2.88Å; N461-D463 VanDerWaalsContact C-N 3.35Å; N461-D463 WeakPolarHBondContact OD1-CB 3.25Å; N461-D463 PolarHBondContact OD1-N 2.93Å; N461-Y466 PolarHBondContact ND2-O 2.82Å; N461-W468 HydrophobicContact CB-CB 4.25Å; N461-W468 HydrophobicContact CB-CE3 4.45Å; N461-W468 PolarHBondContact ND2-N 2.9Å; N461-L511 HydrophobicContact CB-CB 4.3Å; N461-L511 HydrophobicContact CB-CD2 3.83Å; N461-L511 HydrophobicContact CB-CG 3.91Å; N461-L511 PolarHBondContact ND2-O 2.93Å; N461-R512 VanDerWaalsContact ND2-C 3.3Å; N461-R512 PolarHBondContact ND2-O 3.23Å; N461-S513 PolarHBondContact ND2-N 3.47Å; N461-R514 CarbonylContact O-C 3.2Å; N461-R514 WeakPolarHBondContact O-CA 3.11Å; N461-R514 PolarHBondContact O-N 3.02Å; N461-K515 PolarHBondContact N-O 3.38Å; N461-K515 PolarHBondContact O-N 3.02Å
462N97.7Very high95.2Very high0 Ų037.4 Ų37.40%018%0.182CC..  trans-87.4-4.9175.5-167.540000112.3G287 V288 H290 F294 M342 N446 L460 G464G287-N462 PolarHBondContact O-ND2 3.17Å; V288-N462 WeakPolarHBondContact CA-ND2 3.12Å; V288-N462 PolarHBondContact O-ND2 2.66Å; V288-N462 PolarHBondContact O-OD1 3.21Å; H290-N462 PolarHBondContact CE1-ND2 2.72Å; H290-N462 PolarHBondContact CE1-O 3.39Å; F294-N462 HydrophobicContact CD2-CB 3.67Å; F294-N462 HydrophobicContact CE2-CB 3.79Å; M342-N462 HydrophobicContact CE-CB 4.37Å; M342-N462 HydrophobicContact SD-CB 3.77Å; M342-N462 PolarHBondContact SD-OD1 3.39Å; N446-N462 HydrophobicContact CB-CB 4.26Å; N446-N462 WeakPolarHBondContact O-CA 3.17Å; N446-N462 WeakPolarHBondContact O-CB 3.48Å; N446-N462 PolarHBondContact O-N 2.82Å; L460-N462 HydrophobicContact CD2-CB 3.79Å; N462-G464 PolarHBondContact O-N 3.35Å; N462-G464 VanDerWaalsContact O-N 3.13Å
463D94.4Very high95.2Very high19 Ų1940.7 Ų40.710%0.10220%0.198CC..  trans-50.6125.4173.5-173.4-50.3000109.5N446 R447 N461 K465 Y466 S513 R514N446-D463 PolarHBondContact O-N 2.75Å; R447-D463 IonicContact CZ-OD2 2.78Å; R447-D463 VanDerWaalsContact NH2-CB 3.34Å; R447-D463 IonicContact NH2-OD2 2.68Å; R447-D463 PolarHBondContact NH2-OD2 3.28Å; N461-D463 VanDerWaalsContact C-N 3.35Å; N461-D463 WeakPolarHBondContact OD1-CB 3.25Å; N461-D463 PolarHBondContact OD1-N 2.93Å; D463-K465 PolarHBondContact O-N 3.04Å; D463-K465 WeakPolarHBondContact OD1-CA 3.19Å; D463-K465 PolarHBondContact OD1-N 2.88Å; D463-Y466 PolarHBondContact OD1-N 2.79Å; D463-S513 WeakPolarHBondContact O-CA 3.07Å; D463-S513 VanDerWaalsContact O-CB 3.23Å; D463-S513 WeakPolarHBondContact O-CB 3.46Å; D463-S513 PolarHBondContact O-OG 2.98Å; D463-R514 PolarHBondContact O-N 3.32Å
464G89Confident95.2Very high36 Ų3640.5 Ų40.537%0.37120%0.195SC..SBendtrans-78.3-2.6-172.700000114.6N462 S513N462-G464 PolarHBondContact O-N 3.35Å; N462-G464 VanDerWaalsContact O-N 3.13Å; G464-S513 PolarHBondContact O-OG 3.19Å
465K87.4Confident95.2Very high123 Ų12331.7 Ų31.754%0.53517%0.169SC..SBendtrans-135.3-42-172-172.1175.6178.3-161.30113.4D463 S513 L627D463-K465 PolarHBondContact O-N 3.04Å; D463-K465 WeakPolarHBondContact OD1-CA 3.19Å; D463-K465 PolarHBondContact OD1-N 2.88Å; K465-S513 PolarHBondContact N-OG 2.8Å; K465-L627 HydrophobicContact CD-CD2 4.43Å
466Y88.8Confident95.2Very high86 Ų8631 Ų3134%0.33716%0.163SC..  trans-110.4134.6-168.3-56.9-74.6000112.9R447 N461 D463 L627R447-Y466 PolarHBondContact NH2-O 2.85Å; R447-Y466 VanDerWaalsContact NH2-O 3.14Å; N461-Y466 PolarHBondContact ND2-O 2.82Å; D463-Y466 PolarHBondContact OD1-N 2.79Å; Y466-L627 HydrophobicContact CD1-CD2 4.17Å; Y466-L627 HydrophobicContact CE1-CD2 3.38Å; Y466-L627 HydrophobicContact CE1-CG 4.43Å
467S89.2Confident95.1Very high24 Ų2437.8 Ų37.817%0.16819%0.188CC..  trans-64.1147.5165.8-58.20000111.1L511S467-L511 CarbonylContact C-O 3.55Å; S467-L511 WeakPolarHBondContact CA-O 3.28Å
468W92.1Very high94.9Very high0 Ų041 Ų410%021%0.209CC..EExtended strand (participates in β ladder)trans-97.9114.8175.9-164.820.9000109.5I442 E444 R447 A449 N461 R470 L509 F510 L511I442-W468 HydrophobicContact CG1-CZ2 4.49Å; I442-W468 HydrophobicContact CG2-CH2 4.02Å; I442-W468 HydrophobicContact CG2-CZ2 4.13Å; E444-W468 VanDerWaalsContact CD-NE1 3.32Å; E444-W468 HydrophobicContact CG-CZ2 4.43Å; E444-W468 PolarHBondContact OE1-NE1 2.7Å; E444-W468 PolarHBondContact OE2-NE1 2.77Å; R447-W468 HydrophobicContact CB-CD2 4.04Å; R447-W468 HydrophobicContact CB-CE3 3.92Å; R447-W468 HydrophobicContact CB-CH2 3.91Å; R447-W468 HydrophobicContact CB-CZ2 4.01Å; R447-W468 HydrophobicContact CB-CZ3 3.85Å; R447-W468 HydrophobicContact CG-CD2 3.91Å; R447-W468 HydrophobicContact CG-CE3 3.95Å; R447-W468 HydrophobicContact CG-CG 4.23Å; R447-W468 HydrophobicContact CG-CZ3 4.39Å; A449-W468 HydrophobicContact CB-CH2 3.72Å; A449-W468 HydrophobicContact CB-CZ3 3.85Å; N461-W468 HydrophobicContact CB-CB 4.25Å; N461-W468 HydrophobicContact CB-CE3 4.45Å; N461-W468 PolarHBondContact ND2-N 2.9Å; W468-R470 HydrophobicContact CG-CG 4.48Å; W468-L509 HydrophobicContact CD2-CD2 4.05Å; W468-L509 HydrophobicContact CE3-CD2 3.65Å; W468-L509 HydrophobicContact CH2-CD2 4.27Å; W468-L509 HydrophobicContact CZ3-CD2 3.78Å; W468-L509 VanDerWaalsContact O-O 3.05Å; W468-F510 CarbonylContact O-C 3.55Å; W468-F510 VanDerWaalsContact O-CA 3.26Å; W468-F510 WeakPolarHBondContact O-CA 3.39Å; W468-L511 PolarHBondContact N-O 2.95Å; W468-L511 PolarHBondContact O-N 3.37Å
469D90.9Very high94.6Very high55 Ų5541.7 Ų41.729%0.29422%0.217SC..EExtended strand (participates in β ladder)trans-116.6106.7175.8174.526.8000109.4L509 F510 P633D469-L509 CarbonylContact C-O 3.47Å; D469-L509 VanDerWaalsContact CA-O 3.27Å; D469-L509 WeakPolarHBondContact CA-O 3.43Å; D469-F510 HydrophobicContact CB-CD2 4.44Å; D469-P633 HydrophobicContact CB-CB 4.25Å; D469-P633 VanDerWaalsContact CG-CB 3.42Å; D469-P633 WeakPolarHBondContact OD2-CB 3.16Å
470R93.5Very high94.4Very high101 Ų10142 Ų4238%0.38122%0.219SC..EExtended strand (participates in β ladder)trans-146.4145.6-179.1-68.8-62-179.5-95.8-5.3111.8E444 W468 V472 N508 L509E444-R470 IonicContact OE1-CZ 2.71Å; E444-R470 IonicContact OE1-NE 3.78Å; E444-R470 PolarHBondContact OE1-NE 3.49Å; E444-R470 IonicContact OE1-NH2 2.93Å; E444-R470 PolarHBondContact OE1-NH2 3.29Å; E444-R470 IonicContact OE2-CZ 3.83Å; E444-R470 IonicContact OE2-NE 3.08Å; E444-R470 IonicContact OE2-NH2 2.74Å; E444-R470 PolarHBondContact OE2-NH2 3.42Å; W468-R470 HydrophobicContact CG-CG 4.48Å; R470-V472 HydrophobicContact CB-CG1 3.79Å; R470-N508 CarbonylContact O-C 3.59Å; R470-L509 PolarHBondContact N-O 2.9Å; R470-L509 WeakPolarHBondContact O-CA 3.25Å; R470-L509 WeakPolarHBondContact O-CB 3.42Å; R470-L509 PolarHBondContact O-N 3.12Å
471T96.2Very high94.3Very high87 Ų8742 Ų4253%0.53422%0.219SC..EExtended strand (participates in β ladder)trans-84.2120.7158.5-57.10000108.5T506 V507 N508T471-T506 HydrophobicContact CG2-CG2 4.14Å; T471-V507 WeakPolarHBondContact CA-O 3.37Å; T471-N508 PolarHBondContact OG1-OD1 2.85Å; T471-N508 VanDerWaalsContact OG1-OD1 3.07Å
472V97.6Very high94.2Very high7 Ų742.1 Ų42.14%0.04222%0.219CC..EExtended strand (participates in β ladder)trans-124.9146.7-177.2-61.30000110.2I442 F457 R470 T506 V507 L509I442-V472 HydrophobicContact CD1-CG1 4.45Å; I442-V472 HydrophobicContact CG2-CG1 3.95Å; F457-V472 HydrophobicContact CE1-CG2 4.33Å; F457-V472 HydrophobicContact CE2-CG2 4.14Å; F457-V472 HydrophobicContact CZ-CG2 3.56Å; R470-V472 HydrophobicContact CB-CG1 3.79Å; V472-T506 CarbonylContact O-C 3.41Å; V472-T506 WeakPolarHBondContact O-CA 3.09Å; V472-T506 WeakPolarHBondContact O-CB 3.35Å; V472-V507 HydrophobicContact CG2-CB 4.34Å; V472-V507 PolarHBondContact N-O 3.47Å; V472-V507 PolarHBondContact O-N 3.43Å; V472-L509 HydrophobicContact CG1-CB 4.43Å; V472-L509 HydrophobicContact CG1-CD2 4.29Å; V472-L509 HydrophobicContact CG2-CB 3.87Å; V472-L509 HydrophobicContact CG2-CD2 4.34Å
473Q98.2Very high94.1Very high79 Ų7942.2 Ų42.237%0.36922%0.22SC..EExtended strand (participates in β ladder)trans-76.8142.9174.9-173.162.845.900109.8D440 D504 G505D440-Q473 HydrophobicContact CB-CB 4.16Å; D440-Q473 HydrophobicContact CB-CG 4.25Å; D440-Q473 WeakPolarHBondContact OD1-CG 3.5Å; Q473-D504 PolarHBondContact NE2-O 2.97Å; Q473-G505 PolarHBondContact NE2-O 3.49Å
474T98.1Very high94.1Very high4 Ų441.5 Ų41.53%0.02522%0.216CC..  trans-125158.5167.978.70000110.4S451 F457 L476 G505 V507S451-T474 VanDerWaalsContact OG-CA 3.28Å; S451-T474 WeakPolarHBondContact OG-CA 3.46Å; F457-T474 HydrophobicContact CB-CG2 4.22Å; F457-T474 HydrophobicContact CD1-CG2 4.19Å; F457-T474 HydrophobicContact CD2-CG2 3.57Å; F457-T474 HydrophobicContact CE1-CG2 4.49Å; F457-T474 HydrophobicContact CE2-CG2 3.91Å; F457-T474 HydrophobicContact CG-CG2 3.72Å; F457-T474 HydrophobicContact CZ-CG2 4.36Å; T474-L476 VanDerWaalsContact C-N 3.28Å; T474-L476 PolarHBondContact OG1-N 3.49Å; T474-G505 WeakPolarHBondContact CB-O 3.47Å; T474-G505 PolarHBondContact N-O 3.02Å; T474-G505 PolarHBondContact OG1-O 3.06Å; T474-V507 HydrophobicContact CG2-CB 4.14Å; T474-V507 HydrophobicContact CG2-CG2 3.59Å
475G97.5Very high94.4Very high21 Ų2140.7 Ų40.722%0.21620%0.204CC..SBendtrans-82.2-3168.600000114S451 G453 R454S451-G475 PolarHBondContact OG-N 3.21Å; G453-G475 WeakPolarHBondContact O-CA 3.39Å; R454-G475 WeakPolarHBondContact CA-O 3.32Å; R454-G475 WeakPolarHBondContact CG-O 3.45Å
476L98.1Very high94.5Very high7 Ų737.3 Ų37.34%0.03719%0.193CC..SBendtrans-76.7152.3-175.6-70.5170.2000112.2F457 T474 Y481 V501 I519 T521F457-L476 HydrophobicContact CB-CD1 3.89Å; T474-L476 VanDerWaalsContact C-N 3.28Å; T474-L476 PolarHBondContact OG1-N 3.49Å; L476-Y481 HydrophobicContact CD1-CD1 4.43Å; L476-Y481 HydrophobicContact CD1-CE1 4.13Å; L476-Y481 HydrophobicContact CD2-CE1 4.08Å; L476-V501 HydrophobicContact CB-CG1 4.42Å; L476-V501 HydrophobicContact CB-CG2 4.25Å; L476-V501 HydrophobicContact CD1-CG2 4.47Å; L476-I519 HydrophobicContact CD1-CB 4.46Å; L476-I519 HydrophobicContact CD1-CD1 3.53Å; L476-I519 HydrophobicContact CD1-CG1 3.64Å; L476-T521 HydrophobicContact CD2-CG2 4.25Å
477R96.5Very high94.5Very high143 Ų14333.9 Ų33.954%0.5418%0.184SC..PPolyproline II helixtrans-68.4152.3173.463.8177.7178.8129.6-2.2111G479 Y481 V501 M524R477-G479 PolarHBondContact O-N 3.2Å; R477-Y481 WeakPolarHBondContact CG-OH 3.48Å; R477-Y481 WeakPolarHBondContact O-CE2 3.08Å; R477-Y481 PolarHBondContact O-OH 3.47Å; R477-Y481 VanDerWaalsContact O-OH 3.07Å; R477-V501 WeakPolarHBondContact O-CG1 3.33Å; R477-M524 HydrophobicContact CG-SD 3.88Å; R477-M524 VanDerWaalsContact CZ-CE 3.42Å; R477-M524 PolarHBondContact NE-SD 2.79Å; R477-M524 PolarHBondContact NH2-SD 3.35Å
478P94.3Very high94.5Very high68 Ų6836.5 Ų36.544%0.44219%0.194SC..SBendtrans-57.2133.3174-24.334000111.6V501 K502P478-V501 WeakPolarHBondContact CA-O 3.49Å; P478-K502 WeakPolarHBondContact CB-O 3.14Å; P478-K502 WeakPolarHBondContact CG-O 3.33Å
479G93.9Very high94.5Very high16 Ų1638.9 Ų38.917%0.16521%0.208CC..EExtended strand (participates in β ladder)trans170.6-178-171.100000113.3R477 V501R477-G479 PolarHBondContact O-N 3.2Å; G479-V501 PolarHBondContact N-O 3.33Å; G479-V501 PolarHBondContact O-N 3.48Å
480V94.7Very high94.3Very high7 Ų739.9 Ų39.94%0.04222%0.217CC..EExtended strand (participates in β ladder)trans-115.8131.9171.5-174.70000107.1V499 V500 M524 I525 L527 M647V480-V499 WeakPolarHBondContact CA-O 3.5Å; V480-V500 HydrophobicContact CG2-CG2 4.32Å; V480-M524 WeakPolarHBondContact O-CA 3.47Å; V480-I525 HydrophobicContact CB-CD1 3.96Å; V480-I525 HydrophobicContact CB-CG1 3.69Å; V480-I525 HydrophobicContact CG1-CD1 3.67Å; V480-I525 HydrophobicContact CG1-CG1 3.86Å; V480-I525 VanDerWaalsContact O-CG1 3.25Å; V480-I525 WeakPolarHBondContact O-CG1 3.36Å; V480-I525 PolarHBondContact O-N 3.16Å; V480-L527 HydrophobicContact CB-CD1 4.22Å; V480-L527 HydrophobicContact CG2-CD1 3.88Å; V480-M647 HydrophobicContact CG2-CE 3.91Å; V480-M647 HydrophobicContact CG2-CG 3.92Å; V480-M647 HydrophobicContact CG2-SD 4.11Å
481Y95.7Very high93.9Very high0 Ų038.5 Ų38.50%023%0.233CC..EExtended strand (participates in β ladder)trans-125.8141.5-171.3-70.5-102.7000109.2L476 R477 S498 V499 V501 I519 S520 S523 M524L476-Y481 HydrophobicContact CD1-CD1 4.43Å; L476-Y481 HydrophobicContact CD1-CE1 4.13Å; L476-Y481 HydrophobicContact CD2-CE1 4.08Å; R477-Y481 WeakPolarHBondContact CG-OH 3.48Å; R477-Y481 WeakPolarHBondContact O-CE2 3.08Å; R477-Y481 PolarHBondContact O-OH 3.47Å; R477-Y481 VanDerWaalsContact O-OH 3.07Å; Y481-S498 CarbonylContact O-C 3.56Å; Y481-S498 VanDerWaalsContact O-CA 3.32Å; Y481-S498 WeakPolarHBondContact O-CA 3.43Å; Y481-V499 PolarHBondContact N-O 2.93Å; Y481-V499 PolarHBondContact O-N 3.25Å; Y481-V501 HydrophobicContact CD2-CB 4.27Å; Y481-V501 HydrophobicContact CD2-CG2 3.54Å; Y481-V501 HydrophobicContact CE2-CB 3.99Å; Y481-V501 HydrophobicContact CE2-CG2 3.53Å; Y481-V501 HydrophobicContact CG-CG2 4.49Å; Y481-I519 HydrophobicContact CD1-CB 4.34Å; Y481-I519 HydrophobicContact CG-CB 4.38Å; Y481-I519 HydrophobicContact CG-CD1 4.22Å; Y481-S520 WeakPolarHBondContact CD1-O 3.33Å; Y481-S520 VanDerWaalsContact CE1-O 3.24Å; Y481-S520 WeakPolarHBondContact CE1-O 3.43Å; Y481-S523 CarbonylContact C-O 3.32Å; Y481-S523 WeakPolarHBondContact CA-O 3.01Å; Y481-M524 HydrophobicContact CD1-CB 3.82Å; Y481-M524 HydrophobicContact CD1-CG 4.4Å; Y481-M524 HydrophobicContact CD2-CG 4.49Å; Y481-M524 HydrophobicContact CE1-CB 3.59Å; Y481-M524 HydrophobicContact CE1-CG 4.09Å; Y481-M524 HydrophobicContact CE1-SD 4.18Å; Y481-M524 HydrophobicContact CE2-CG 4.15Å; Y481-M524 HydrophobicContact CE2-SD 3.9Å; Y481-M524 HydrophobicContact CG-CB 4.41Å; Y481-M524 VanDerWaalsContact CZ-SD 3.56Å; Y481-M524 PolarHBondContact OH-SD 3.24Å; Y481-M524 VanDerWaalsContact OH-SD 3.38Å
482C94.6Very high93.5Very high1 Ų137.9 Ų37.91%0.00722%0.224CC..EExtended strand (participates in β ladder)trans-84.3127.3171.2-54.40000109.3M484 V489 C494 S523C482-M484 PolarHBondContact O-N 3.2Å; C482-V489 HydrophobicContact CB-CG2 4.13Å; C482-V489 VanDerWaalsContact SG-CG2 3.53Å; C482-C494 WeakPolarHBondContact CA-SG 3.49Å; C482-C494 HydrophobicContact CB-CB 3.7Å; C482-C494 WeakPolarHBondContact CB-SG 3.5Å; C482-C494 WeakPolarHBondContact SG-CA 3.45Å; C482-C494 WeakPolarHBondContact SG-CB 3.5Å; C482-C494 CovalentContact SG-SG 2.03Å; C482-C494 PolarHBondContact SG-SG 3.43Å; C482-S523 PolarHBondContact N-O 3.06Å; C482-S523 WeakPolarHBondContact O-CB 3.49Å; C482-S523 PolarHBondContact O-OG 3.23Å
483D94.7Very high93Very high3 Ų338.4 Ų38.42%0.01623%0.228CC..  trans-61.9110.9170.3172.425.1000109.4V485 T486 G487 K497 V499 M517 A518D483-V485 PolarHBondContact O-N 2.96Å; D483-V485 VanDerWaalsContact O-N 3.16Å; D483-V485 PolarHBondContact OD1-N 2.95Å; D483-V485 VanDerWaalsContact OD1-N 3.16Å; D483-T486 WeakPolarHBondContact CB-OG1 2.86Å; D483-T486 PolarHBondContact O-N 2.99Å; D483-T486 VanDerWaalsContact O-N 3.16Å; D483-T486 WeakPolarHBondContact OD2-CB 3.47Å; D483-T486 VanDerWaalsContact OD2-CG2 3.26Å; D483-T486 WeakPolarHBondContact OD2-CG2 3.28Å; D483-T486 PolarHBondContact OD2-OG1 3.13Å; D483-G487 CarbonylContact O-C 2.92Å; D483-G487 PolarHBondContact O-N 3.38Å; D483-K497 HydrophobicContact CB-CB 4.05Å; D483-K497 WeakPolarHBondContact CB-O 3.01Å; D483-K497 PolarHBondContact N-O 3.45Å; D483-V499 HydrophobicContact CB-CG2 4.36Å; D483-M517 HydrophobicContact CB-CG 4.31Å; D483-M517 WeakPolarHBondContact OD1-CA 3.3Å; D483-A518 PolarHBondContact OD1-N 3.24Å; D483-A518 VanDerWaalsContact OD1-N 3.07Å
484M95.6Very high92.6Very high4 Ų435.6 Ų35.62%0.0222%0.217CC..THydrogen-bonded Turntrans-64-21.6-175.3-62.1-17870.400112R425 L428 F429 C482 G487 A518 S520R425-M484 HydrophobicContact CB-CB 4.48Å; R425-M484 WeakPolarHBondContact CB-O 3.16Å; R425-M484 VanDerWaalsContact CG-O 3.23Å; R425-M484 WeakPolarHBondContact CG-O 3.49Å; L428-M484 HydrophobicContact CB-CE 3.89Å; F429-M484 HydrophobicContact CB-CE 4.11Å; F429-M484 HydrophobicContact CB-SD 4.01Å; F429-M484 HydrophobicContact CD2-SD 3.94Å; F429-M484 HydrophobicContact CG-SD 4.49Å; C482-M484 PolarHBondContact O-N 3.2Å; M484-G487 WeakPolarHBondContact CA-O 3.38Å; M484-A518 WeakPolarHBondContact CB-O 3.08Å; M484-A518 WeakPolarHBondContact CG-O 3.49Å; M484-A518 PolarHBondContact N-O 3.25Å; M484-S520 PolarHBondContact SD-OG 2.8Å
485V94.2Very high92.1Very high18 Ų1839 Ų3911%0.10924%0.238CC..THydrogen-bonded Turntrans-75.3-39.6177.7177.40000111.3F341 T422 M426 D483 V516 A518F341-V485 HydrophobicContact CE1-CG1 3.72Å; F341-V485 HydrophobicContact CZ-CG1 3.65Å; F341-V485 HydrophobicContact CZ-CG2 4.17Å; T422-V485 HydrophobicContact CG2-CG1 4.38Å; M426-V485 HydrophobicContact SD-CG2 3.93Å; D483-V485 PolarHBondContact O-N 2.96Å; D483-V485 VanDerWaalsContact O-N 3.16Å; D483-V485 PolarHBondContact OD1-N 2.95Å; D483-V485 VanDerWaalsContact OD1-N 3.16Å; V485-V516 HydrophobicContact CG2-CG1 4.21Å; V485-A518 HydrophobicContact CG2-CB 4.14Å
486T89.7Confident91.5Very high52 Ų5238.2 Ų38.232%0.31923%0.23SC..THydrogen-bonded Turntrans-101.7-9.3-174.157.90000113.9D483 G496 K497 A581D483-T486 WeakPolarHBondContact CB-OG1 2.86Å; D483-T486 PolarHBondContact O-N 2.99Å; D483-T486 VanDerWaalsContact O-N 3.16Å; D483-T486 WeakPolarHBondContact OD2-CB 3.47Å; D483-T486 VanDerWaalsContact OD2-CG2 3.26Å; D483-T486 WeakPolarHBondContact OD2-CG2 3.28Å; D483-T486 PolarHBondContact OD2-OG1 3.13Å; T486-G496 WeakPolarHBondContact O-CA 3.49Å; T486-K497 WeakPolarHBondContact OG1-CB 3.35Å; T486-K497 PolarHBondContact OG1-N 3.06Å; T486-K497 VanDerWaalsContact OG1-N 3.17Å; T486-A581 HydrophobicContact CG2-CB 4.4Å
487G88.3Confident91Very high14 Ų1438.6 Ų38.614%0.14423%0.231CC..  trans179.6-154173.300000114.2D483 M484 T495D483-G487 CarbonylContact O-C 2.92Å; D483-G487 PolarHBondContact O-N 3.38Å; M484-G487 WeakPolarHBondContact CA-O 3.38Å; G487-T495 WeakPolarHBondContact CA-OG1 3.49Å
488E89.6Confident90.8Very high79 Ų7932 Ų3237%0.36921%0.207SC..  trans-151.8171.5-172.866.8-173.1175.400112.5R425 V490 C494 T495R425-E488 IonicContact CZ-OE2 2.93Å; R425-E488 IonicContact NH1-OE2 3.7Å; R425-E488 PolarHBondContact NH1-OE2 3.07Å; E488-V490 HydrophobicContact CG-CG2 4.33Å; E488-C494 WeakPolarHBondContact O-CA 3.28Å; E488-T495 HydrophobicContact CG-CG2 4.34Å; E488-T495 PolarHBondContact N-OG1 3.44Å; E488-T495 PolarHBondContact O-N 3.03Å; E488-T495 PolarHBondContact O-OG1 2.94Å
489V91.9Very high90.7Very high50 Ų5029 Ų2930%0.30319%0.187SC..EExtended strand (participates in β ladder)trans-79.2120.8176.2177.60000109.3C482 S523 I525C482-V489 HydrophobicContact CB-CG2 4.13Å; C482-V489 VanDerWaalsContact SG-CG2 3.53Å; V489-S523 WeakPolarHBondContact CG2-O 3.39Å; V489-I525 HydrophobicContact CB-CG2 4.44Å; V489-I525 HydrophobicContact CG1-CG2 3.79Å; V489-I525 HydrophobicContact CG2-CG2 4.04Å
490V87.5Confident90.7Very high77 Ų7729.8 Ų29.847%0.46719%0.189SC..EExtended strand (participates in β ladder)trans-123.4109.6167.4176.90000108.4E488 Q492 S493 T495E488-V490 HydrophobicContact CG-CG2 4.33Å; V490-Q492 PolarHBondContact O-N 2.95Å; V490-S493 PolarHBondContact N-O 3.46Å; V490-S493 PolarHBondContact O-N 2.99Å; V490-T495 HydrophobicContact CB-CG2 4.17Å; V490-T495 HydrophobicContact CG2-CG2 3.47Å; V490-T495 VanDerWaalsContact CG2-CG2 3.47Å
491G86.1Confident90.7Very high71 Ų7129.6 Ų29.673%0.73219%0.188SC*.THydrogen-bonded Turntrans62.6-107-175.800000112.1
492Q86.9Confident90.6Very high75 Ų7533 Ų3335%0.3520%0.203SC..THydrogen-bonded Turntrans-121.323.1176.6-51.8-178-63.300112.4V490 L527 V575V490-Q492 PolarHBondContact O-N 2.95Å; Q492-L527 HydrophobicContact CB-CD2 4.4Å; Q492-V575 WeakPolarHBondContact O-CG2 3.13Å
493S87.7Confident90.5Very high18 Ų1842.3 Ų42.313%0.12624%0.243CC..EExtended strand (participates in β ladder)trans-131.4160.9-178.8-59.20000110.1V490 N595V490-S493 PolarHBondContact N-O 3.46Å; V490-S493 PolarHBondContact O-N 2.99Å; S493-N595 PolarHBondContact OG-OD1 3.39Å; S493-N595 VanDerWaalsContact OG-OD1 3.04Å
494C89.3Confident90.6Very high20 Ų2047 Ų4714%0.13527%0.268CS..EExtended strand (participates in β ladder)trans-99.7137.1171.6-58.40000109.7C482 E488 G496 S498C482-C494 WeakPolarHBondContact CA-SG 3.49Å; C482-C494 HydrophobicContact CB-CB 3.7Å; C482-C494 WeakPolarHBondContact CB-SG 3.5Å; C482-C494 WeakPolarHBondContact SG-CA 3.45Å; C482-C494 WeakPolarHBondContact SG-CB 3.5Å; C482-C494 CovalentContact SG-SG 2.03Å; C482-C494 PolarHBondContact SG-SG 3.43Å; E488-C494 WeakPolarHBondContact O-CA 3.28Å; C494-G496 VanDerWaalsContact C-N 3.27Å; C494-G496 WeakPolarHBondContact CB-O 3.32Å; C494-S498 WeakPolarHBondContact CB-OG 3.49Å; C494-S498 PolarHBondContact SG-OG 3.36Å
495T86.4Confident90.6Very high76 Ų7647.1 Ų47.147%0.46627%0.27SS..SBendtrans-75.5-23.7169.9570000112G487 E488 V490G487-T495 WeakPolarHBondContact CA-OG1 3.49Å; E488-T495 HydrophobicContact CG-CG2 4.34Å; E488-T495 PolarHBondContact N-OG1 3.44Å; E488-T495 PolarHBondContact O-N 3.03Å; E488-T495 PolarHBondContact O-OG1 2.94Å; V490-T495 HydrophobicContact CB-CG2 4.17Å; V490-T495 HydrophobicContact CG2-CG2 3.47Å; V490-T495 VanDerWaalsContact CG2-CG2 3.47Å
496G85.2Confident90.8Very high3 Ų346.9 Ų46.93%0.03127%0.269CS..SBendtrans-111.6-156.2175.600000112.4T486 C494 T580T486-G496 WeakPolarHBondContact O-CA 3.49Å; C494-G496 VanDerWaalsContact C-N 3.27Å; C494-G496 WeakPolarHBondContact CB-O 3.32Å; G496-T580 WeakPolarHBondContact CA-OG1 3.36Å
497K87.7Confident91Very high16 Ų1644.5 Ų44.57%0.0725%0.254CS..  trans-64.7136.1179.5179.9178.5-172.8165.90110.7D483 T486 F510 E579 T580D483-K497 HydrophobicContact CB-CB 4.05Å; D483-K497 WeakPolarHBondContact CB-O 3.01Å; D483-K497 PolarHBondContact N-O 3.45Å; T486-K497 WeakPolarHBondContact OG1-CB 3.35Å; T486-K497 PolarHBondContact OG1-N 3.06Å; T486-K497 VanDerWaalsContact OG1-N 3.17Å; K497-F510 PolarHBondContact NZ-O 2.91Å; K497-E579 HydrophobicContact CD-CG 4.31Å; K497-E579 IonicContact NZ-OE1 3.84Å; K497-E579 PolarHBondContact NZ-OE1 3.12Å; K497-T580 PolarHBondContact N-OG1 3.47Å; K497-T580 VanDerWaalsContact N-OG1 3.14Å
498S92.3Very high91.2Very high4 Ų446.1 Ų46.13%0.02826%0.26CS..EExtended strand (participates in β ladder)trans-94.6146.2167.8-50.20000110.7Y481 C494 R576Y481-S498 CarbonylContact O-C 3.56Å; Y481-S498 VanDerWaalsContact O-CA 3.32Å; Y481-S498 WeakPolarHBondContact O-CA 3.43Å; C494-S498 WeakPolarHBondContact CB-OG 3.49Å; C494-S498 PolarHBondContact SG-OG 3.36Å; S498-R576 VanDerWaalsContact CB-O 3.27Å; S498-R576 WeakPolarHBondContact CB-O 3.4Å; S498-R576 PolarHBondContact OG-O 3.29Å
499V93.4Very high91.4Very high6 Ų642.4 Ų42.44%0.03624%0.242CC..EExtended strand (participates in β ladder)trans-124126178.7-174.60000108.5V480 Y481 D483 V507 M517 I519V480-V499 WeakPolarHBondContact CA-O 3.5Å; Y481-V499 PolarHBondContact N-O 2.93Å; Y481-V499 PolarHBondContact O-N 3.25Å; D483-V499 HydrophobicContact CB-CG2 4.36Å; V499-V507 HydrophobicContact CG1-CB 4.46Å; V499-V507 HydrophobicContact CG1-CG1 3.46Å; V499-V507 VanDerWaalsContact CG1-CG1 3.46Å; V499-V507 HydrophobicContact CG1-CG2 4.07Å; V499-M517 HydrophobicContact CG1-SD 4.27Å; V499-M517 HydrophobicContact CG2-CE 3.89Å; V499-M517 HydrophobicContact CG2-CG 4.36Å; V499-M517 HydrophobicContact CG2-SD 3.8Å; V499-I519 HydrophobicContact CB-CD1 4.21Å; V499-I519 HydrophobicContact CB-CG2 4.11Å; V499-I519 HydrophobicContact CG1-CD1 3.91Å; V499-I519 HydrophobicContact CG2-CG2 3.92Å
500V93.2Very high91.4Very high31 Ų3140.9 Ų40.919%0.18823%0.232CC..EExtended strand (participates in β ladder)trans-96.5113.9-179.6-1760000109.5V480 V577 M647V480-V500 HydrophobicContact CG2-CG2 4.32Å; V500-V577 HydrophobicContact CG2-CG1 3.99Å; V500-V577 HydrophobicContact CG2-CG2 4.2Å; V500-M647 HydrophobicContact CG2-SD 3.94Å
501V95.2Very high91.5Very high4 Ų437.4 Ų37.42%0.02421%0.21CC..EExtended strand (participates in β ladder)trans-86.4115167.7-176.60000107.8L476 R477 P478 G479 Y481 V507 I519L476-V501 HydrophobicContact CB-CG1 4.42Å; L476-V501 HydrophobicContact CB-CG2 4.25Å; L476-V501 HydrophobicContact CD1-CG2 4.47Å; R477-V501 WeakPolarHBondContact O-CG1 3.33Å; P478-V501 WeakPolarHBondContact CA-O 3.49Å; G479-V501 PolarHBondContact N-O 3.33Å; G479-V501 PolarHBondContact O-N 3.48Å; Y481-V501 HydrophobicContact CD2-CB 4.27Å; Y481-V501 HydrophobicContact CD2-CG2 3.54Å; Y481-V501 HydrophobicContact CE2-CB 3.99Å; Y481-V501 HydrophobicContact CE2-CG2 3.53Å; Y481-V501 HydrophobicContact CG-CG2 4.49Å; V501-V507 HydrophobicContact CB-CG2 4.3Å; V501-V507 HydrophobicContact CG2-CG2 3.71Å; V501-I519 HydrophobicContact CG2-CD1 4.07Å
502K93.6Very high91.7Very high72 Ų7235.4 Ų35.431%0.31318%0.181SC..  trans-71.2172.6-177.4-63.2-175.5-162.6165.80111.6P478 D504 G505 T506 N508P478-K502 WeakPolarHBondContact CB-O 3.14Å; P478-K502 WeakPolarHBondContact CG-O 3.33Å; K502-D504 VanDerWaalsContact CB-OD1 3.32Å; K502-D504 WeakPolarHBondContact CB-OD1 3.43Å; K502-D504 PolarHBondContact O-N 3.01Å; K502-G505 PolarHBondContact O-N 2.68Å; K502-T506 WeakPolarHBondContact CB-O 3.48Å; K502-T506 PolarHBondContact N-O 2.73Å; K502-N508 WeakPolarHBondContact CE-ND2 3.37Å; K502-N508 WeakPolarHBondContact CE-OD1 3.27Å; K502-N508 PolarHBondContact NZ-ND2 2.97Å; K502-N508 PolarHBondContact NZ-OD1 2.84Å
503K92.7Very high91.9Very high195 Ų19533.4 Ų33.485%0.84818%0.175SC*.THydrogen-bonded Turntrans-60.2-27.2-178.3-72.5-174.2176.8-177.70114.3G505K503-G505 VanDerWaalsContact C-N 3.31Å
504D95.5Very high92.2Very high101 Ų10137.1 Ų37.154%0.5419%0.186SC..THydrogen-bonded Turntrans-88.63.9176.857.55.5000113Q473 K502 T506Q473-D504 PolarHBondContact NE2-O 2.97Å; K502-D504 VanDerWaalsContact CB-OD1 3.32Å; K502-D504 WeakPolarHBondContact CB-OD1 3.43Å; K502-D504 PolarHBondContact O-N 3.01Å; D504-T506 VanDerWaalsContact C-N 3.28Å; D504-T506 WeakPolarHBondContact OD1-CB 3.3Å; D504-T506 PolarHBondContact OD1-N 2.66Å; D504-T506 PolarHBondContact OD1-OG1 3.44Å; D504-T506 PolarHBondContact OD2-OG1 2.78Å
505G96Very high92.4Very high7 Ų739.9 Ų39.97%0.07220%0.196CC..SBendtrans81.13.4-177.200000113.9Q473 T474 K502 K503Q473-G505 PolarHBondContact NE2-O 3.49Å; T474-G505 WeakPolarHBondContact CB-O 3.47Å; T474-G505 PolarHBondContact N-O 3.02Å; T474-G505 PolarHBondContact OG1-O 3.06Å; K502-G505 PolarHBondContact O-N 2.68Å; K503-G505 VanDerWaalsContact C-N 3.31Å
506T97.6Very high92.9Very high14 Ų1436.5 Ų36.59%0.08618%0.175CC..EExtended strand (participates in β ladder)trans-83152.9177.766.20000112.6T471 V472 K502 D504T471-T506 HydrophobicContact CG2-CG2 4.14Å; V472-T506 CarbonylContact O-C 3.41Å; V472-T506 WeakPolarHBondContact O-CA 3.09Å; V472-T506 WeakPolarHBondContact O-CB 3.35Å; K502-T506 WeakPolarHBondContact CB-O 3.48Å; K502-T506 PolarHBondContact N-O 2.73Å; D504-T506 VanDerWaalsContact C-N 3.28Å; D504-T506 WeakPolarHBondContact OD1-CB 3.3Å; D504-T506 PolarHBondContact OD1-N 2.66Å; D504-T506 PolarHBondContact OD1-OG1 3.44Å; D504-T506 PolarHBondContact OD2-OG1 2.78Å
507V95.4Very high93.4Very high1 Ų136.5 Ų36.51%0.00617%0.174CC..EExtended strand (participates in β ladder)trans-118.9137.7170.4170.30000108.5T471 V472 T474 V499 V501 L509T471-V507 WeakPolarHBondContact CA-O 3.37Å; V472-V507 HydrophobicContact CG2-CB 4.34Å; V472-V507 PolarHBondContact N-O 3.47Å; V472-V507 PolarHBondContact O-N 3.43Å; T474-V507 HydrophobicContact CG2-CB 4.14Å; T474-V507 HydrophobicContact CG2-CG2 3.59Å; V499-V507 HydrophobicContact CG1-CB 4.46Å; V499-V507 HydrophobicContact CG1-CG1 3.46Å; V499-V507 VanDerWaalsContact CG1-CG1 3.46Å; V499-V507 HydrophobicContact CG1-CG2 4.07Å; V501-V507 HydrophobicContact CB-CG2 4.3Å; V501-V507 HydrophobicContact CG2-CG2 3.71Å; V507-L509 VanDerWaalsContact C-N 3.32Å; V507-L509 PolarHBondContact O-N 2.68Å; V507-L509 VanDerWaalsContact O-N 3.15Å
508N92.8Very high93.9Very high49 Ų4935.7 Ų35.726%0.26217%0.171SC..EExtended strand (participates in β ladder)trans-79.187.5162.4-72.6-16.2000107.7R470 T471 K502 F510 Y634R470-N508 CarbonylContact O-C 3.59Å; T471-N508 PolarHBondContact OG1-OD1 2.85Å; T471-N508 VanDerWaalsContact OG1-OD1 3.07Å; K502-N508 WeakPolarHBondContact CE-ND2 3.37Å; K502-N508 WeakPolarHBondContact CE-OD1 3.27Å; K502-N508 PolarHBondContact NZ-ND2 2.97Å; K502-N508 PolarHBondContact NZ-OD1 2.84Å; N508-F510 PolarHBondContact O-N 2.86Å; N508-F510 VanDerWaalsContact O-N 3.15Å; N508-Y634 PolarHBondContact ND2-OH 2.9Å
509L93Very high94.2Very high0 Ų035.5 Ų35.50%017%0.17CC..EExtended strand (participates in β ladder)trans-69.8107.9179.2176.863.1000108.8A449 A459 W468 D469 R470 V472 V507 L511 M517A449-L509 HydrophobicContact CB-CD2 4.27Å; A459-L509 HydrophobicContact CB-CD1 3.8Å; A459-L509 HydrophobicContact CB-CD2 3.83Å; A459-L509 HydrophobicContact CB-CG 4.49Å; W468-L509 HydrophobicContact CD2-CD2 4.05Å; W468-L509 HydrophobicContact CE3-CD2 3.65Å; W468-L509 HydrophobicContact CH2-CD2 4.27Å; W468-L509 HydrophobicContact CZ3-CD2 3.78Å; W468-L509 VanDerWaalsContact O-O 3.05Å; D469-L509 CarbonylContact C-O 3.47Å; D469-L509 VanDerWaalsContact CA-O 3.27Å; D469-L509 WeakPolarHBondContact CA-O 3.43Å; R470-L509 PolarHBondContact N-O 2.9Å; R470-L509 WeakPolarHBondContact O-CA 3.25Å; R470-L509 WeakPolarHBondContact O-CB 3.42Å; R470-L509 PolarHBondContact O-N 3.12Å; V472-L509 HydrophobicContact CG1-CB 4.43Å; V472-L509 HydrophobicContact CG1-CD2 4.29Å; V472-L509 HydrophobicContact CG2-CB 3.87Å; V472-L509 HydrophobicContact CG2-CD2 4.34Å; V507-L509 VanDerWaalsContact C-N 3.32Å; V507-L509 PolarHBondContact O-N 2.68Å; V507-L509 VanDerWaalsContact O-N 3.15Å; L509-L511 HydrophobicContact CD1-CB 4.05Å; L509-L511 HydrophobicContact CG-CB 4.44Å; L509-M517 HydrophobicContact CD1-CE 3.49Å; L509-M517 VanDerWaalsContact CD1-CE 3.49Å; L509-M517 HydrophobicContact CD1-SD 4.01Å
510F91.3Very high94.4Very high19 Ų1935.2 Ų35.28%0.08317%0.168CC..EExtended strand (participates in β ladder)trans-110.6111.4163.2179.7-123.2000108.4W468 D469 K497 N508 E579 F631 P633W468-F510 CarbonylContact O-C 3.55Å; W468-F510 VanDerWaalsContact O-CA 3.26Å; W468-F510 WeakPolarHBondContact O-CA 3.39Å; D469-F510 HydrophobicContact CB-CD2 4.44Å; K497-F510 PolarHBondContact NZ-O 2.91Å; N508-F510 PolarHBondContact O-N 2.86Å; N508-F510 VanDerWaalsContact O-N 3.15Å; F510-E579 WeakPolarHBondContact CE1-OE2 3.13Å; F510-F631 AromaticContact CE2-CD1 3.76Å; F510-F631 HydrophobicContact CE2-CD1 3.76Å; F510-F631 AromaticContact CE2-CE1 3.93Å; F510-F631 HydrophobicContact CE2-CE1 3.93Å; F510-F631 HydrophobicContact CZ-CD1 4.13Å; F510-F631 VanDerWaalsContact CZ-O 3.25Å; F510-F631 WeakPolarHBondContact CZ-O 3.42Å; F510-P633 HydrophobicContact CB-CG 4.1Å; F510-P633 HydrophobicContact CD1-CG 4.49Å; F510-P633 HydrophobicContact CD2-CG 3.8Å; F510-P633 HydrophobicContact CE2-CG 4.36Å; F510-P633 HydrophobicContact CG-CG 3.88Å
511L91.1Very high94.6Very high4 Ų436.4 Ų36.42%0.02118%0.175CC..EExtended strand (participates in β ladder)trans-131.9117.2-177.5-170.260.1000110.3A459 N461 S467 W468 L509 K515 M517A459-L511 HydrophobicContact CB-CD2 3.96Å; A459-L511 WeakPolarHBondContact O-CD2 3.33Å; N461-L511 HydrophobicContact CB-CB 4.3Å; N461-L511 HydrophobicContact CB-CD2 3.83Å; N461-L511 HydrophobicContact CB-CG 3.91Å; N461-L511 PolarHBondContact ND2-O 2.93Å; S467-L511 CarbonylContact C-O 3.55Å; S467-L511 WeakPolarHBondContact CA-O 3.28Å; W468-L511 PolarHBondContact N-O 2.95Å; W468-L511 PolarHBondContact O-N 3.37Å; L509-L511 HydrophobicContact CD1-CB 4.05Å; L509-L511 HydrophobicContact CG-CB 4.44Å; L511-K515 HydrophobicContact CD1-CB 3.83Å; L511-K515 WeakPolarHBondContact CD2-O 3.24Å; L511-K515 HydrophobicContact CG-CB 4.29Å; L511-M517 HydrophobicContact CD1-CB 4Å
512R89.8Confident94.7Very high29 Ų2938.9 Ų38.911%0.10920%0.196CC..  trans-61.4160.7-179.3-67.3-176.4179.5-76.8-11.8112.8N461 R514 K515 E579 K629N461-R512 VanDerWaalsContact ND2-C 3.3Å; N461-R512 PolarHBondContact ND2-O 3.23Å; R512-R514 PolarHBondContact O-N 2.93Å; R512-K515 HydrophobicContact CB-CG 4Å; R512-K515 PolarHBondContact O-N 2.81Å; R512-E579 IonicContact CZ-OE2 3.51Å; R512-E579 IonicContact NE-OE1 3.15Å; R512-E579 IonicContact NE-OE2 2.62Å; R512-E579 PolarHBondContact NE-OE2 3.17Å; R512-E579 IonicContact NH2-OE2 3.03Å; R512-E579 PolarHBondContact NH2-OE2 3.12Å; R512-K629 PolarHBondContact NH1-O 3.21Å
513S90.7Very high94.8Very high32 Ų3235.5 Ų35.522%0.22418%0.182CC..THydrogen-bonded Turntrans-49.2134.3170.4154.60000110.8N461 D463 G464 K465 K515N461-S513 PolarHBondContact ND2-N 3.47Å; D463-S513 WeakPolarHBondContact O-CA 3.07Å; D463-S513 VanDerWaalsContact O-CB 3.23Å; D463-S513 WeakPolarHBondContact O-CB 3.46Å; D463-S513 PolarHBondContact O-OG 2.98Å; G464-S513 PolarHBondContact O-OG 3.19Å; K465-S513 PolarHBondContact N-OG 2.8Å; S513-K515 VanDerWaalsContact C-N 3.33Å; S513-K515 PolarHBondContact O-N 3.1Å
514R93.3Very high95Very high96 Ų9627.7 Ų27.736%0.36215%0.149SC..THydrogen-bonded Turntrans5736.4-180-54.9-179-175.9-74.6-2.4114.9H290 M342 N461 D463 R512H290-R514 PolarHBondContact NE2-NH1 3.03Å; H290-R514 PolarHBondContact NE2-NH2 3.1Å; M342-R514 HydrophobicContact CE-CB 4.26Å; N461-R514 CarbonylContact O-C 3.2Å; N461-R514 WeakPolarHBondContact O-CA 3.11Å; N461-R514 PolarHBondContact O-N 3.02Å; D463-R514 PolarHBondContact O-N 3.32Å; R512-R514 PolarHBondContact O-N 2.93Å
515K93.9Very high94.8Very high78 Ų7823.1 Ų23.134%0.33912%0.124SC..EExtended strand (participates in β ladder)trans-123157.9177.7-62.1-61.7169.5-167.50112.3D338 N461 L511 R512 S513D338-K515 IonicContact OD2-NZ 2.73Å; D338-K515 PolarHBondContact OD2-NZ 3.09Å; N461-K515 PolarHBondContact N-O 3.38Å; N461-K515 PolarHBondContact O-N 3.02Å; L511-K515 HydrophobicContact CD1-CB 3.83Å; L511-K515 WeakPolarHBondContact CD2-O 3.24Å; L511-K515 HydrophobicContact CG-CB 4.29Å; R512-K515 HydrophobicContact CB-CG 4Å; R512-K515 PolarHBondContact O-N 2.81Å; S513-K515 VanDerWaalsContact C-N 3.33Å; S513-K515 PolarHBondContact O-N 3.1Å
516V96.8Very high94.3Very high6 Ų626.9 Ų26.94%0.03615%0.149CC..EExtended strand (participates in β ladder)trans-124.1146.8178.4178.70000107.8F341 M342 A345 F458 A459 L460 V485F341-V516 HydrophobicContact CE1-CB 4.27Å; M342-V516 HydrophobicContact CB-CG2 4.32Å; M342-V516 HydrophobicContact CG-CG2 3.9Å; A345-V516 HydrophobicContact CB-CG1 4.05Å; F458-V516 HydrophobicContact CD2-CG1 4.12Å; F458-V516 HydrophobicContact CE2-CG1 3.26Å; F458-V516 HydrophobicContact CZ-CG1 3.52Å; A459-V516 CarbonylContact O-C 3.42Å; A459-V516 WeakPolarHBondContact O-CA 3.46Å; L460-V516 HydrophobicContact CB-CG2 4.37Å; L460-V516 HydrophobicContact CD1-CG2 4.33Å; L460-V516 HydrophobicContact CG-CG2 4.13Å; V485-V516 HydrophobicContact CG2-CG1 4.21Å
517M96.3Very high94Very high2 Ų227.8 Ų27.81%0.0115%0.153CC..EExtended strand (participates in β ladder)trans-131.1140.4172.1175.5-152.4-70.800108.5A459 D483 V499 L509 L511A459-M517 PolarHBondContact N-O 3.2Å; A459-M517 PolarHBondContact O-N 2.71Å; D483-M517 HydrophobicContact CB-CG 4.31Å; D483-M517 WeakPolarHBondContact OD1-CA 3.3Å; V499-M517 HydrophobicContact CG1-SD 4.27Å; V499-M517 HydrophobicContact CG2-CE 3.89Å; V499-M517 HydrophobicContact CG2-CG 4.36Å; V499-M517 HydrophobicContact CG2-SD 3.8Å; L509-M517 HydrophobicContact CD1-CE 3.49Å; L509-M517 VanDerWaalsContact CD1-CE 3.49Å; L509-M517 HydrophobicContact CD1-SD 4.01Å; L511-M517 HydrophobicContact CD1-CB 4Å
518A98.3Very high93.8Very high0 Ų031 Ų310%017%0.174CC..EExtended strand (participates in β ladder)trans-139.8129.8170.800000110.3M426 F429 F457 F458 D483 M484 V485M426-A518 HydrophobicContact CE-CB 4.14Å; M426-A518 HydrophobicContact SD-CB 3.64Å; F429-A518 HydrophobicContact CD2-CB 3.77Å; F429-A518 HydrophobicContact CE2-CB 3.98Å; F429-A518 HydrophobicContact CG-CB 4.05Å; F429-A518 HydrophobicContact CZ-CB 4.45Å; F457-A518 WeakPolarHBondContact O-CA 3.5Å; F458-A518 HydrophobicContact CD2-CB 4.21Å; D483-A518 PolarHBondContact OD1-N 3.24Å; D483-A518 VanDerWaalsContact OD1-N 3.07Å; M484-A518 WeakPolarHBondContact CB-O 3.08Å; M484-A518 WeakPolarHBondContact CG-O 3.49Å; M484-A518 PolarHBondContact N-O 3.25Å; V485-A518 HydrophobicContact CG2-CB 4.14Å
519I98.1Very high93.7Very high0 Ų040 Ų400%021%0.205CC..EExtended strand (participates in β ladder)trans-130.2139174.354.9168.4000110F429 G456 F457 L476 Y481 V499 V501F429-I519 WeakPolarHBondContact CE2-O 3.4Å; G456-I519 CarbonylContact C-O 3.59Å; G456-I519 WeakPolarHBondContact CA-O 3.3Å; F457-I519 HydrophobicContact CB-CD1 4.43Å; F457-I519 HydrophobicContact CB-CG1 3.94Å; F457-I519 HydrophobicContact CD1-CD1 4.46Å; F457-I519 HydrophobicContact CD1-CG1 4.23Å; F457-I519 PolarHBondContact N-O 2.79Å; F457-I519 PolarHBondContact O-N 3.12Å; L476-I519 HydrophobicContact CD1-CB 4.46Å; L476-I519 HydrophobicContact CD1-CD1 3.53Å; L476-I519 HydrophobicContact CD1-CG1 3.64Å; Y481-I519 HydrophobicContact CD1-CB 4.34Å; Y481-I519 HydrophobicContact CG-CB 4.38Å; Y481-I519 HydrophobicContact CG-CD1 4.22Å; V499-I519 HydrophobicContact CB-CD1 4.21Å; V499-I519 HydrophobicContact CB-CG2 4.11Å; V499-I519 HydrophobicContact CG1-CD1 3.91Å; V499-I519 HydrophobicContact CG2-CG2 3.92Å; V501-I519 HydrophobicContact CG2-CD1 4.07Å
520S98.2Very high93.8Very high0 Ų041.6 Ų41.60%022%0.215CC..EExtended strand (participates in β ladder)trans-133.1171.1178.974.90000112.7S455 Y481 M484 A522 S523S455-S520 CarbonylContact O-C 3.52Å; S455-S520 WeakPolarHBondContact O-CA 3.44Å; S455-S520 WeakPolarHBondContact O-CB 3.35Å; Y481-S520 WeakPolarHBondContact CD1-O 3.33Å; Y481-S520 VanDerWaalsContact CE1-O 3.24Å; Y481-S520 WeakPolarHBondContact CE1-O 3.43Å; M484-S520 PolarHBondContact SD-OG 2.8Å; S520-A522 PolarHBondContact O-N 3.23Å; S520-A522 PolarHBondContact OG-N 3.16Å; S520-S523 PolarHBondContact N-OG 3.3Å; S520-S523 PolarHBondContact O-N 3.38Å; S520-S523 PolarHBondContact O-OG 2.92Å
521T97.5Very high93.9Very high55 Ų5541.3 Ų41.334%0.33721%0.214SC..G310 helixtrans-50.6-39.9172.237.50000113.7E432 S455 L476 S523 M524E432-T521 PolarHBondContact OE2-OG1 3.19Å; S455-T521 PolarHBondContact O-N 3.1Å; S455-T521 PolarHBondContact O-OG1 2.91Å; L476-T521 HydrophobicContact CD2-CG2 4.25Å; T521-S523 VanDerWaalsContact C-N 3.28Å; T521-S523 PolarHBondContact O-N 3.08Å; T521-M524 WeakPolarHBondContact O-CB 3.23Å; T521-M524 PolarHBondContact O-N 2.81Å
522A96.1Very high94.1Very high57 Ų5745.4 Ų45.447%0.47123%0.232SC..G310 helixtrans-69.6-21.9175.500000114.4E432 S520 M524E432-A522 HydrophobicContact CG-CB 3.86Å; E432-A522 WeakPolarHBondContact OE1-CB 3.24Å; E432-A522 VanDerWaalsContact OE2-CB 3.25Å; E432-A522 WeakPolarHBondContact OE2-CB 3.5Å; E432-A522 PolarHBondContact OE2-N 2.96Å; S520-A522 PolarHBondContact O-N 3.23Å; S520-A522 PolarHBondContact OG-N 3.16Å; A522-M524 VanDerWaalsContact C-N 3.29Å; A522-M524 PolarHBondContact O-N 2.95Å
523S96.5Very high94.3Very high1 Ų145.4 Ų45.41%0.00723%0.233CC..G310 helixtrans-85.62.7177.872.50000114Y481 C482 V489 S520 T521Y481-S523 CarbonylContact C-O 3.32Å; Y481-S523 WeakPolarHBondContact CA-O 3.01Å; C482-S523 PolarHBondContact N-O 3.06Å; C482-S523 WeakPolarHBondContact O-CB 3.49Å; C482-S523 PolarHBondContact O-OG 3.23Å; V489-S523 WeakPolarHBondContact CG2-O 3.39Å; S520-S523 PolarHBondContact N-OG 3.3Å; S520-S523 PolarHBondContact O-N 3.38Å; S520-S523 PolarHBondContact O-OG 2.92Å; T521-S523 VanDerWaalsContact C-N 3.28Å; T521-S523 PolarHBondContact O-N 3.08Å
524M95.9Very high94.6Very high31 Ų3143.9 Ų43.915%0.15322%0.222CC..EExtended strand (participates in β ladder)trans-76.9129.3-177.8-172.9164.8163.200112.6R477 V480 Y481 T521 A522R477-M524 HydrophobicContact CG-SD 3.88Å; R477-M524 VanDerWaalsContact CZ-CE 3.42Å; R477-M524 PolarHBondContact NE-SD 2.79Å; R477-M524 PolarHBondContact NH2-SD 3.35Å; V480-M524 WeakPolarHBondContact O-CA 3.47Å; Y481-M524 HydrophobicContact CD1-CB 3.82Å; Y481-M524 HydrophobicContact CD1-CG 4.4Å; Y481-M524 HydrophobicContact CD2-CG 4.49Å; Y481-M524 HydrophobicContact CE1-CB 3.59Å; Y481-M524 HydrophobicContact CE1-CG 4.09Å; Y481-M524 HydrophobicContact CE1-SD 4.18Å; Y481-M524 HydrophobicContact CE2-CG 4.15Å; Y481-M524 HydrophobicContact CE2-SD 3.9Å; Y481-M524 HydrophobicContact CG-CB 4.41Å; Y481-M524 VanDerWaalsContact CZ-SD 3.56Å; Y481-M524 PolarHBondContact OH-SD 3.24Å; Y481-M524 VanDerWaalsContact OH-SD 3.38Å; T521-M524 WeakPolarHBondContact O-CB 3.23Å; T521-M524 PolarHBondContact O-N 2.81Å; A522-M524 VanDerWaalsContact C-N 3.29Å; A522-M524 PolarHBondContact O-N 2.95Å
525I92.5Very high94.8Very high4 Ų439.3 Ų39.32%0.02121%0.205CC..EExtended strand (participates in β ladder)trans-92.9125.2166.158171.4000110.5V480 V489 L527 V575V480-I525 HydrophobicContact CB-CD1 3.96Å; V480-I525 HydrophobicContact CB-CG1 3.69Å; V480-I525 HydrophobicContact CG1-CD1 3.67Å; V480-I525 HydrophobicContact CG1-CG1 3.86Å; V480-I525 VanDerWaalsContact O-CG1 3.25Å; V480-I525 WeakPolarHBondContact O-CG1 3.36Å; V480-I525 PolarHBondContact O-N 3.16Å; V489-I525 HydrophobicContact CB-CG2 4.44Å; V489-I525 HydrophobicContact CG1-CG2 3.79Å; V489-I525 HydrophobicContact CG2-CG2 4.04Å; I525-L527 HydrophobicContact CD1-CD1 4.09Å; I525-L527 HydrophobicContact CD1-CD2 4.34Å; I525-L527 HydrophobicContact CD1-CG 4.2Å; I525-L527 HydrophobicContact CG1-CG 4.29Å; I525-L527 PolarHBondContact O-N 3.11Å; I525-V575 HydrophobicContact CD1-CG1 3.71Å; I525-V575 HydrophobicContact CD1-CG2 4.49Å
526S85.5Confident94.9Very high86 Ų8635.6 Ų35.660%0.60119%0.189SC*.  trans-81.999.5178.2-177.40000110.6
527L90.9Very high94.9Very high33 Ų3335.3 Ų35.317%0.17319%0.187CC..  trans-97.7139.8175.1-61-178.6000112V480 Q492 I525 F531 V575 M647V480-L527 HydrophobicContact CB-CD1 4.22Å; V480-L527 HydrophobicContact CG2-CD1 3.88Å; Q492-L527 HydrophobicContact CB-CD2 4.4Å; I525-L527 HydrophobicContact CD1-CD1 4.09Å; I525-L527 HydrophobicContact CD1-CD2 4.34Å; I525-L527 HydrophobicContact CD1-CG 4.2Å; I525-L527 HydrophobicContact CG1-CG 4.29Å; I525-L527 PolarHBondContact O-N 3.11Å; L527-F531 HydrophobicContact CB-CB 4.13Å; L527-F531 HydrophobicContact CB-CD2 4.28Å; L527-F531 HydrophobicContact CB-CG 4.1Å; L527-F531 HydrophobicContact CD1-CB 4.32Å; L527-F531 HydrophobicContact CD1-CD1 4.05Å; L527-F531 HydrophobicContact CD1-CG 4.24Å; L527-F531 HydrophobicContact CD2-CD1 4.48Å; L527-F531 HydrophobicContact CD2-CE1 4.43Å; L527-V575 HydrophobicContact CD1-CB 4.49Å; L527-V575 HydrophobicContact CD1-CG2 4.12Å; L527-V575 HydrophobicContact CD2-CG2 3.96Å; L527-M647 HydrophobicContact CD1-CB 3.96Å; L527-M647 HydrophobicContact CD1-CG 4.13Å
528P91.5Very high95Very high68 Ų6835.2 Ų35.244%0.44219%0.187SC..  trans-55.1151.9170.6-25.333.1000112.7S530 F531P528-S530 PolarHBondContact O-N 3.04Å; P528-F531 HydrophobicContact CB-CD2 4.16Å; P528-F531 HydrophobicContact CG-CD2 4.17Å; P528-F531 HydrophobicContact CG-CE2 4.08Å; P528-F531 WeakPolarHBondContact O-CB 3.19Å; P528-F531 PolarHBondContact O-N 3.01Å
529R90.2Very high94.9Very high240 Ų24040.1 Ų40.191%0.90621%0.205SC*.THydrogen-bonded Turntrans-58.8-18.9177.7-70.2-176.1179.6176.61.3114F531 K532R529-F531 PolarHBondContact O-N 3.3Å; R529-K532 PolarHBondContact O-NZ 2.84Å
530S94.8Very high94.7Very high32 Ų3241.5 Ų41.522%0.22421%0.211CC..THydrogen-bonded Turntrans-66.8-24175.257.90000112.6P528 K532 D649 C650P528-S530 PolarHBondContact O-N 3.04Å; S530-K532 PolarHBondContact O-N 2.78Å; S530-D649 WeakPolarHBondContact CB-OD1 3.46Å; S530-D649 PolarHBondContact OG-OD1 3.17Å; S530-C650 VanDerWaalsContact O-CB 3.27Å; S530-C650 WeakPolarHBondContact O-CB 3.48Å; S530-C650 PolarHBondContact O-N 2.95Å; S530-C650 PolarHBondContact O-SG 2.97Å; S530-C650 VanDerWaalsContact O-SG 3.37Å
531F94.7Very high94.5Very high13 Ų1347.9 Ų47.96%0.05724%0.241CC..EExtended strand (participates in β ladder)trans-68.2131175.2-78.6-105.9000110.9L527 P528 R529 R573 V575 M647 M648 D649L527-F531 HydrophobicContact CB-CB 4.13Å; L527-F531 HydrophobicContact CB-CD2 4.28Å; L527-F531 HydrophobicContact CB-CG 4.1Å; L527-F531 HydrophobicContact CD1-CB 4.32Å; L527-F531 HydrophobicContact CD1-CD1 4.05Å; L527-F531 HydrophobicContact CD1-CG 4.24Å; L527-F531 HydrophobicContact CD2-CD1 4.48Å; L527-F531 HydrophobicContact CD2-CE1 4.43Å; P528-F531 HydrophobicContact CB-CD2 4.16Å; P528-F531 HydrophobicContact CG-CD2 4.17Å; P528-F531 HydrophobicContact CG-CE2 4.08Å; P528-F531 WeakPolarHBondContact O-CB 3.19Å; P528-F531 PolarHBondContact O-N 3.01Å; R529-F531 PolarHBondContact O-N 3.3Å; F531-R573 HydrophobicContact CE1-CG 4.31Å; F531-R573 HydrophobicContact CZ-CB 4.18Å; F531-R573 HydrophobicContact CZ-CG 3.93Å; F531-V575 HydrophobicContact CE1-CG2 4.27Å; F531-M647 HydrophobicContact CB-CB 4.49Å; F531-M647 HydrophobicContact CB-CE 4.26Å; F531-M647 HydrophobicContact CD1-CB 3.97Å; F531-M648 CarbonylContact C-O 3.6Å; F531-M648 VanDerWaalsContact CA-O 3.23Å; F531-M648 WeakPolarHBondContact CA-O 3.4Å; F531-D649 HydrophobicContact CD1-CB 4.41Å; F531-D649 HydrophobicContact CD2-CB 4.04Å; F531-D649 HydrophobicContact CE1-CB 4.02Å; F531-D649 HydrophobicContact CE2-CB 3.6Å; F531-D649 HydrophobicContact CG-CB 4.44Å; F531-D649 HydrophobicContact CZ-CB 3.61Å
532K95.1Very high94.4Very high91 Ų9146.4 Ų46.440%0.39623%0.232SC..EExtended strand (participates in β ladder)trans-134140175.2-57.8-67.2176.7-133.30110.5R529 S530 T534 M648 C650R529-K532 PolarHBondContact O-NZ 2.84Å; S530-K532 PolarHBondContact O-N 2.78Å; K532-T534 PolarHBondContact O-N 3.39Å; K532-T534 PolarHBondContact O-OG1 2.83Å; K532-M648 PolarHBondContact N-O 2.91Å; K532-M648 PolarHBondContact O-N 2.91Å; K532-C650 VanDerWaalsContact CB-SG 3.55Å; K532-C650 WeakPolarHBondContact CG-SG 3.36Å
533H94.3Very high94.2Very high28 Ų2849.9 Ų49.913%0.1324%0.241CC..EExtended strand (participates in β ladder)trans-58.9119.7171.6-171.1-167.7000109.1Y634 D645 V646 M647 G697 I714H533-Y634 AromaticContact CE1-CZ 3.94Å; H533-Y634 PolarHBondContact CE1-OH 3.46Å; H533-D645 IonicContact CD2-OD1 3.53Å; H533-D645 PolarHBondContact CD2-OD1 2.04Å; H533-D645 IonicContact CE1-OD1 2.68Å; H533-D645 IonicContact NE2-OD1 2.65Å; H533-D645 PolarHBondContact NE2-OD1 3Å; H533-D645 IonicContact NE2-OD2 3.43Å; H533-V646 CarbonylContact C-O 3.57Å; H533-V646 WeakPolarHBondContact CA-O 3.39Å; H533-M647 HydrophobicContact CB-SD 3.82Å; H533-G697 CarbonylContact O-C 3.52Å; H533-G697 WeakPolarHBondContact O-CA 3.42Å; H533-I714 WeakPolarHBondContact O-CD1 3.49Å
534T96.7Very high93.7Very high0 Ų061.2 Ų61.20%029%0.286CS..EExtended strand (participates in β ladder)trans-135123.4-173.2-55.90000107.7K532 V646 M648 F658 G697K532-T534 PolarHBondContact O-N 3.39Å; K532-T534 PolarHBondContact O-OG1 2.83Å; T534-V646 PolarHBondContact N-O 3.1Å; T534-V646 PolarHBondContact O-N 2.94Å; T534-V646 VanDerWaalsContact O-N 3.08Å; T534-M648 HydrophobicContact CG2-CE 4.09Å; T534-M648 HydrophobicContact CG2-SD 4.28Å; T534-F658 HydrophobicContact CG2-CE1 3.82Å; T534-F658 HydrophobicContact CG2-CZ 4.04Å; T534-G697 PolarHBondContact OG1-N 2.96Å
535I96.4Very high93.3Very high0 Ų062.1 Ų62.10%030%0.302CS..EExtended strand (participates in β ladder)trans-115.9135.7-179.4-60172.7000107.9F537 Y634 M643 F644 D645 Y698 L699 N700 I714I535-F537 HydrophobicContact CG2-CD2 3.93Å; I535-F537 HydrophobicContact CG2-CE2 3.83Å; I535-Y634 HydrophobicContact CD1-CD1 3.63Å; I535-Y634 HydrophobicContact CD1-CD2 3.82Å; I535-Y634 HydrophobicContact CD1-CE1 3.78Å; I535-Y634 HydrophobicContact CD1-CE2 3.98Å; I535-Y634 HydrophobicContact CD1-CG 3.65Å; I535-M643 HydrophobicContact CG2-CG 3.87Å; I535-M643 HydrophobicContact CG2-SD 4.27Å; I535-F644 CarbonylContact C-O 3.49Å; I535-F644 VanDerWaalsContact CA-O 3.31Å; I535-F644 WeakPolarHBondContact CA-O 3.49Å; I535-D645 HydrophobicContact CG1-CB 4.36Å; I535-Y698 PolarHBondContact N-O 3.48Å; I535-L699 HydrophobicContact CB-CB 4.42Å; I535-L699 HydrophobicContact CB-CG 4.22Å; I535-L699 HydrophobicContact CG2-CG 4.27Å; I535-L699 CarbonylContact O-C 3.51Å; I535-L699 WeakPolarHBondContact O-CA 3.45Å; I535-N700 PolarHBondContact O-N 3.18Å; I535-N700 PolarHBondContact O-ND2 3.3Å; I535-I714 HydrophobicContact CB-CD1 4.24Å; I535-I714 HydrophobicContact CD1-CD1 3.92Å; I535-I714 HydrophobicContact CG1-CD1 3.83Å
536V97.4Very high93.4Very high0 Ų063.1 Ų63.10%031%0.307CS..EExtended strand (participates in β ladder)trans-121.5123170.7-178.70000109I538 L550 M619 M643 F644 F658 F660 N700 Y702V536-I538 HydrophobicContact CG1-CD1 3.85Å; V536-I538 HydrophobicContact CG1-CG1 4.24Å; V536-L550 HydrophobicContact CB-CD1 4.05Å; V536-L550 HydrophobicContact CG1-CD1 4.05Å; V536-L550 HydrophobicContact CG2-CD1 4.39Å; V536-M619 VanDerWaalsContact O-CE 3.3Å; V536-M619 WeakPolarHBondContact O-CE 3.23Å; V536-M643 CarbonylContact O-C 3.6Å; V536-M643 WeakPolarHBondContact O-CA 3.35Å; V536-F644 HydrophobicContact CB-CB 4.24Å; V536-F644 HydrophobicContact CB-CD1 4.4Å; V536-F644 HydrophobicContact CG2-CD1 4.25Å; V536-F644 PolarHBondContact N-O 3.4Å; V536-F644 PolarHBondContact O-N 2.62Å; V536-F658 HydrophobicContact CG2-CE2 4.21Å; V536-F658 HydrophobicContact CG2-CZ 3.82Å; V536-F660 HydrophobicContact CG1-CE1 4.45Å; V536-F660 HydrophobicContact CG1-CE2 4.21Å; V536-F660 HydrophobicContact CG1-CZ 3.94Å; V536-N700 CarbonylContact C-O 3.56Å; V536-N700 WeakPolarHBondContact CA-O 3.08Å; V536-N700 HydrophobicContact CG2-CB 4.32Å; V536-Y702 HydrophobicContact CG1-CD2 4.05Å; V536-Y702 HydrophobicContact CG1-CE2 4.01Å
537F97.1Very high93.8Very high0 Ų060.6 Ų60.60%029%0.286CS..EExtended strand (participates in β ladder)trans-107.4127.7173.1-88.9-63.7000110.3I535 T622 Y634 N635 Y637 F641 W642 M643 L699 N700 V701 Y702I535-F537 HydrophobicContact CG2-CD2 3.93Å; I535-F537 HydrophobicContact CG2-CE2 3.83Å; F537-T622 HydrophobicContact CE1-CG2 4.36Å; F537-Y634 WeakPolarHBondContact CE2-O 3.22Å; F537-N635 HydrophobicContact CE1-CB 3.94Å; F537-N635 HydrophobicContact CZ-CB 3.84Å; F537-Y637 HydrophobicContact CD2-CD2 4.2Å; F537-Y637 AromaticContact CD2-CE2 3.8Å; F537-Y637 HydrophobicContact CD2-CE2 3.8Å; F537-Y637 HydrophobicContact CE2-CE2 4.14Å; F537-Y637 HydrophobicContact CG-CD2 4.42Å; F537-Y637 HydrophobicContact CG-CE2 4.41Å; F537-F641 HydrophobicContact CB-CD1 3.96Å; F537-F641 HydrophobicContact CD1-CB 3.91Å; F537-F641 HydrophobicContact CD1-CD1 4.28Å; F537-F641 HydrophobicContact CE1-CB 4.37Å; F537-F641 HydrophobicContact CG-CD1 4.41Å; F537-W642 CarbonylContact C-O 3.45Å; F537-W642 VanDerWaalsContact CA-O 3.25Å; F537-W642 WeakPolarHBondContact CA-O 3.43Å; F537-M643 HydrophobicContact CD1-CB 3.94Å; F537-M643 HydrophobicContact CD1-CG 4.12Å; F537-M643 HydrophobicContact CE1-CB 3.52Å; F537-M643 HydrophobicContact CE1-CG 3.6Å; F537-M643 HydrophobicContact CE1-SD 3.97Å; F537-M643 HydrophobicContact CE2-CG 4.27Å; F537-M643 HydrophobicContact CE2-SD 4.29Å; F537-M643 HydrophobicContact CZ-CB 4.11Å; F537-M643 HydrophobicContact CZ-CG 3.67Å; F537-M643 HydrophobicContact CZ-SD 3.56Å; F537-M643 VanDerWaalsContact CZ-SD 3.56Å; F537-L699 HydrophobicContact CD2-CD2 4.1Å; F537-L699 HydrophobicContact CD2-CG 4.3Å; F537-L699 HydrophobicContact CE2-CD1 4.36Å; F537-N700 PolarHBondContact N-O 3.07Å; F537-V701 HydrophobicContact CB-CG1 4.24Å; F537-V701 CarbonylContact O-C 3.58Å; F537-Y702 PolarHBondContact O-N 2.75Å
538I96.8Very high94.1Very high1 Ų159 Ų591%0.00528%0.277CS..EExtended strand (participates in β ladder)trans-119.3116.9174.6-54.5-59.9000109V536 K540 L550 M619 F641 W642 F660 A662 Y702 F704V536-I538 HydrophobicContact CG1-CD1 3.85Å; V536-I538 HydrophobicContact CG1-CG1 4.24Å; I538-K540 HydrophobicContact CG2-CB 4.47Å; I538-K540 PolarHBondContact O-N 2.8Å; I538-L550 HydrophobicContact CG1-CD2 4.27Å; I538-M619 HydrophobicContact CB-CE 4.24Å; I538-M619 HydrophobicContact CB-SD 4.21Å; I538-M619 HydrophobicContact CG1-CE 3.67Å; I538-M619 HydrophobicContact CG1-SD 3.7Å; I538-F641 WeakPolarHBondContact O-CA 3.28Å; I538-W642 PolarHBondContact N-O 3.14Å; I538-W642 PolarHBondContact O-N 2.88Å; I538-F660 HydrophobicContact CD1-CE2 3.8Å; I538-F660 HydrophobicContact CD1-CZ 4.23Å; I538-A662 HydrophobicContact CB-CB 4.48Å; I538-A662 HydrophobicContact CD1-CB 4.17Å; I538-A662 HydrophobicContact CG1-CB 3.9Å; I538-A662 HydrophobicContact CG2-CB 3.92Å; I538-Y702 HydrophobicContact CD1-CD2 3.8Å; I538-Y702 HydrophobicContact CD1-CG 3.98Å; I538-F704 HydrophobicContact CG2-CB 4.02Å; I538-F704 HydrophobicContact CG2-CD2 4.08Å
539R96Very high94.3Very high103 Ų10355.9 Ų55.939%0.38926%0.257SS..EExtended strand (participates in β ladder)trans-74.6111.6168.9-167.8175.5165.5-90.5-6.4109.8H640 F641 Y702 D703 F704R539-H640 CarbonylContact C-O 3.57Å; R539-H640 VanDerWaalsContact CA-O 3.29Å; R539-H640 WeakPolarHBondContact CA-O 3.38Å; R539-F641 HydrophobicContact CB-CD1 3.98Å; R539-F641 HydrophobicContact CB-CD2 4.4Å; R539-F641 HydrophobicContact CB-CE1 3.57Å; R539-F641 HydrophobicContact CB-CE2 3.99Å; R539-F641 HydrophobicContact CB-CG 4.41Å; R539-F641 HydrophobicContact CB-CZ 3.58Å; R539-F641 HydrophobicContact CG-CD2 4.25Å; R539-F641 HydrophobicContact CG-CE1 4.32Å; R539-F641 HydrophobicContact CG-CE2 3.82Å; R539-F641 HydrophobicContact CG-CZ 3.89Å; R539-Y702 PolarHBondContact N-O 3.01Å; R539-D703 HydrophobicContact CB-CB 4.38Å; R539-D703 WeakPolarHBondContact CD-OD2 3.36Å; R539-D703 IonicContact CZ-OD2 2.67Å; R539-D703 IonicContact NH1-OD2 3.78Å; R539-D703 PolarHBondContact NH1-OD2 2.93Å; R539-F704 WeakPolarHBondContact O-CB 3.28Å; R539-F704 PolarHBondContact O-N 3.33Å
540K95.6Very high94.6Very high29 Ų2944.5 Ų44.513%0.12621%0.214CC..  trans-146.4112.9174.2176.151.9169166.90108.6I538 T542 V548 H640 W642 T664 Q668 F704I538-K540 HydrophobicContact CG2-CB 4.47Å; I538-K540 PolarHBondContact O-N 2.8Å; K540-T542 HydrophobicContact CG-CG2 3.82Å; K540-T542 PolarHBondContact O-N 3.06Å; K540-V548 HydrophobicContact CB-CG2 4.27Å; K540-V548 HydrophobicContact CG-CG2 4.05Å; K540-H640 PolarHBondContact N-O 2.89Å; K540-W642 PolarHBondContact O-NE1 2.92Å; K540-T664 HydrophobicContact CG-CG2 4.34Å; K540-Q668 VanDerWaalsContact NZ-OE1 3.11Å; K540-F704 HydrophobicContact CB-CB 3.85Å; K540-F704 HydrophobicContact CB-CD2 4.12Å; K540-F704 HydrophobicContact CB-CG 4.1Å; K540-F704 HydrophobicContact CD-CB 4.05Å; K540-F704 HydrophobicContact CD-CD1 3.78Å; K540-F704 HydrophobicContact CD-CD2 4.14Å; K540-F704 HydrophobicContact CD-CE1 4.25Å; K540-F704 HydrophobicContact CD-CG 3.73Å; K540-F704 HydrophobicContact CG-CB 4.3Å; K540-F704 HydrophobicContact CG-CD2 4.05Å; K540-F704 HydrophobicContact CG-CG 4.07Å
541E94.4Very high94.7Very high133 Ų13346.1 Ų46.162%0.62122%0.215SC*.  trans-66.8121.1167.9-173.3170-170.300108.7H640E541-H640 HydrophobicContact CB-CB 4.43Å
542T93.9Very high94.7Very high24 Ų2445.5 Ų45.515%0.14721%0.213CC..  trans-121.3157.5179.554.60000109.9K540 Q546 V548 W621 W642K540-T542 HydrophobicContact CG-CG2 3.82Å; K540-T542 PolarHBondContact O-N 3.06Å; T542-Q546 VanDerWaalsContact CA-OE1 3.28Å; T542-Q546 HydrophobicContact CG2-CB 4.47Å; T542-Q546 HydrophobicContact CG2-CG 4.26Å; T542-V548 HydrophobicContact CG2-CG2 4.03Å; T542-W621 WeakPolarHBondContact OG1-CZ3 3.43Å; T542-W642 HydrophobicContact CG2-CZ2 3.67Å; T542-W642 WeakPolarHBondContact OG1-CZ2 3.44Å
543I91.4Very high94.7Very high131 Ų13141.2 Ų41.267%0.67219%0.194SC*.  trans-88.8162.616860.2173.4000110.3G545 Q546I543-G545 PolarHBondContact O-N 3.44Å; I543-Q546 HydrophobicContact CG1-CB 3.94Å; I543-Q546 WeakPolarHBondContact O-CB 3.21Å; I543-Q546 PolarHBondContact O-N 2.85Å
544Y86.6Confident94.7Very high239 Ų23940.1 Ų40.194%0.93719%0.189SC*.THydrogen-bonded Turntrans-55.6129.1175.3-176.1-93.1000110.9
545G87.7Confident94.4Very high49 Ų4943.2 Ų43.251%0.50520%0.204SC..THydrogen-bonded Turntrans86-2.4-177.700000115.5I543 H547I543-G545 PolarHBondContact O-N 3.44Å; G545-H547 PolarHBondContact O-CD2 3.25Å
546Q93.8Very high93.9Very high26 Ų2649.9 Ų49.912%0.12123%0.233CC..  trans-92.5131.6170.9-171.9-174.431.700110.1T542 I543 W642 D665 D666T542-Q546 VanDerWaalsContact CA-OE1 3.28Å; T542-Q546 HydrophobicContact CG2-CB 4.47Å; T542-Q546 HydrophobicContact CG2-CG 4.26Å; I543-Q546 HydrophobicContact CG1-CB 3.94Å; I543-Q546 WeakPolarHBondContact O-CB 3.21Å; I543-Q546 PolarHBondContact O-N 2.85Å; Q546-W642 WeakPolarHBondContact O-CH2 3.34Å; Q546-W642 WeakPolarHBondContact O-CZ2 3.43Å; Q546-D665 WeakPolarHBondContact CA-OD2 3.09Å; Q546-D665 WeakPolarHBondContact CG-OD1 3.4Å; Q546-D666 PolarHBondContact NE2-OD1 2.98Å
547H94.9Very high93.3Very high32 Ų3254.6 Ų54.615%0.14826%0.255CS..  trans-116.8153.1-176.2-61.1-86.6000112.8G545 F549 W590 T664 D665G545-H547 PolarHBondContact O-CD2 3.25Å; H547-F549 HydrophobicContact CB-CE2 3.76Å; H547-F549 HydrophobicContact CB-CZ 4.16Å; H547-W590 HydrophobicContact CB-CZ3 4.06Å; H547-W590 AromaticContact CD2-CH2 3.88Å; H547-W590 AromaticContact CD2-CZ3 3.85Å; H547-W590 AromaticContact CG-CZ3 3.69Å; H547-W590 AromaticContact ND1-CZ3 3.97Å; H547-T664 WeakPolarHBondContact O-CA 3.38Å; H547-D665 IonicContact CD2-OD2 3.21Å; H547-D665 PolarHBondContact N-OD2 3.22Å; H547-D665 PolarHBondContact O-N 3.15Å; H547-D665 VanDerWaalsContact O-N 3.1Å
548V96.3Very high92.8Very high0 Ų056.4 Ų56.40%027%0.266CS..EExtended strand (participates in β ladder)trans-113.3137.9175.3-1780000110K540 T542 M619 W642 A662 I663 T664K540-V548 HydrophobicContact CB-CG2 4.27Å; K540-V548 HydrophobicContact CG-CG2 4.05Å; T542-V548 HydrophobicContact CG2-CG2 4.03Å; V548-M619 HydrophobicContact CB-SD 4.43Å; V548-M619 HydrophobicContact CG1-CG 4.31Å; V548-M619 HydrophobicContact CG1-SD 3.65Å; V548-M619 WeakPolarHBondContact O-CB 3.46Å; V548-M619 PolarHBondContact O-N 3.09Å; V548-W642 HydrophobicContact CB-CB 4.28Å; V548-W642 HydrophobicContact CB-CD2 3.68Å; V548-W642 HydrophobicContact CB-CE3 4.11Å; V548-W642 HydrophobicContact CB-CG 3.77Å; V548-W642 HydrophobicContact CG1-CG 4.42Å; V548-W642 HydrophobicContact CG2-CD2 3.7Å; V548-W642 VanDerWaalsContact CG2-CE2 3.43Å; V548-W642 HydrophobicContact CG2-CE3 4.49Å; V548-W642 HydrophobicContact CG2-CG 3.77Å; V548-W642 HydrophobicContact CG2-CZ2 4.06Å; V548-A662 HydrophobicContact CG1-CB 4.26Å; V548-I663 CarbonylContact C-O 3.6Å; V548-I663 WeakPolarHBondContact CA-O 3.41Å; V548-T664 HydrophobicContact CG2-CG2 4.18Å
549F96.9Very high92.4Very high3 Ų357.4 Ų57.41%0.01328%0.275CS..EExtended strand (participates in β ladder)trans-125.3155.8179.2-59.5-98.5000110.2H547 W590 A614 I615 S617 P618 A662 I663 D665H547-F549 HydrophobicContact CB-CE2 3.76Å; H547-F549 HydrophobicContact CB-CZ 4.16Å; F549-W590 HydrophobicContact CE1-CD2 4.19Å; F549-W590 AromaticContact CE1-CE3 3.85Å; F549-W590 HydrophobicContact CE1-CE3 3.85Å; F549-W590 HydrophobicContact CE1-CZ3 4.19Å; F549-W590 HydrophobicContact CZ-CD2 4.23Å; F549-W590 AromaticContact CZ-CE3 3.71Å; F549-W590 HydrophobicContact CZ-CE3 3.71Å; F549-W590 AromaticContact CZ-CH2 3.96Å; F549-W590 HydrophobicContact CZ-CH2 3.96Å; F549-W590 HydrophobicContact CZ-CZ2 4.45Å; F549-W590 AromaticContact CZ-CZ3 3.56Å; F549-W590 HydrophobicContact CZ-CZ3 3.56Å; F549-A614 HydrophobicContact CD1-CB 4.34Å; F549-A614 HydrophobicContact CE1-CB 3.83Å; F549-I615 HydrophobicContact CB-CG1 4.06Å; F549-I615 HydrophobicContact CD1-CG1 4.09Å; F549-I615 HydrophobicContact CD2-CD1 3.78Å; F549-I615 HydrophobicContact CD2-CG1 3.37Å; F549-I615 HydrophobicContact CE1-CG1 4.41Å; F549-I615 HydrophobicContact CE2-CD1 4.24Å; F549-I615 HydrophobicContact CE2-CG1 3.75Å; F549-I615 HydrophobicContact CG-CD1 4.33Å; F549-I615 HydrophobicContact CG-CG1 3.57Å; F549-I615 HydrophobicContact CZ-CG1 4.25Å; F549-S617 CarbonylContact C-O 3.47Å; F549-S617 WeakPolarHBondContact CA-O 3.32Å; F549-P618 HydrophobicContact CD1-CB 4Å; F549-P618 HydrophobicContact CE1-CB 3.89Å; F549-A662 CarbonylContact O-C 3.56Å; F549-A662 WeakPolarHBondContact O-CA 3.23Å; F549-I663 PolarHBondContact N-O 3.47Å; F549-I663 PolarHBondContact O-N 2.96Å; F549-D665 HydrophobicContact CE2-CB 4.19Å
550L96.7Very high92Very high0 Ų057.1 Ų57.10%029%0.286CS..EExtended strand (participates in β ladder)trans-105.4133.4165.4-66-174000110.6V536 I538 L597 S617 M619 F644 F660 A662V536-L550 HydrophobicContact CB-CD1 4.05Å; V536-L550 HydrophobicContact CG1-CD1 4.05Å; V536-L550 HydrophobicContact CG2-CD1 4.39Å; I538-L550 HydrophobicContact CG1-CD2 4.27Å; L550-L597 HydrophobicContact CB-CD1 3.95Å; L550-S617 PolarHBondContact N-O 2.93Å; L550-S617 PolarHBondContact O-N 3.46Å; L550-M619 HydrophobicContact CD1-CE 4.21Å; L550-M619 HydrophobicContact CD1-SD 4.32Å; L550-M619 HydrophobicContact CD2-CE 4.38Å; L550-M619 HydrophobicContact CD2-SD 3.69Å; L550-M619 HydrophobicContact CG-CE 4.23Å; L550-M619 HydrophobicContact CG-CG 3.94Å; L550-M619 HydrophobicContact CG-SD 3.69Å; L550-F644 HydrophobicContact CD1-CB 3.58Å; L550-F644 HydrophobicContact CD1-CD1 3.66Å; L550-F644 HydrophobicContact CD1-CD2 4.26Å; L550-F644 HydrophobicContact CD1-CE1 4.35Å; L550-F644 HydrophobicContact CD1-CG 3.59Å; L550-F644 HydrophobicContact CG-CB 4.44Å; L550-F660 HydrophobicContact CD2-CD2 3.69Å; L550-F660 HydrophobicContact CD2-CE2 4.08Å; L550-A662 HydrophobicContact CD2-CB 3.9Å
551R95.9Very high91.7Very high67 Ų6758.7 Ų58.725%0.25331%0.305SS..EExtended strand (participates in β ladder)trans-112.6138.8157.8-70.1-171.9-174.7172.1-0.4108.3N598 W599 I615 F660 K661 I663R551-N598 WeakPolarHBondContact CA-O 3.49Å; R551-W599 HydrophobicContact CB-CE3 4.17Å; R551-I615 VanDerWaalsContact CZ-O 3.24Å; R551-I615 PolarHBondContact NE-O 2.69Å; R551-I615 PolarHBondContact NH2-O 2.91Å; R551-F660 CarbonylContact O-C 3.56Å; R551-F660 WeakPolarHBondContact O-CA 3.24Å; R551-F660 VanDerWaalsContact O-CB 3.28Å; R551-F660 WeakPolarHBondContact O-CB 3.38Å; R551-K661 PolarHBondContact N-O 3.09Å; R551-K661 PolarHBondContact O-N 3.4Å; R551-I663 HydrophobicContact CB-CD1 4.11Å; R551-I663 HydrophobicContact CG-CD1 3.79Å
552G95.6Very high91.4Very high0 Ų052.7 Ų52.70%028%0.277CS..EExtended strand (participates in β ladder)trans-175.1-168.3-177.700000114.4L597 N598 W599 E659G552-L597 CarbonylContact O-C 3.55Å; G552-L597 VanDerWaalsContact O-C 3.32Å; G552-N598 PolarHBondContact N-O 3.35Å; G552-N598 VanDerWaalsContact N-O 3.09Å; G552-N598 CarbonylContact O-C 3.53Å; G552-N598 WeakPolarHBondContact O-CA 3.36Å; G552-N598 PolarHBondContact O-N 2.86Å; G552-N598 VanDerWaalsContact O-N 3.16Å; G552-W599 PolarHBondContact O-N 2.78Å; G552-W599 VanDerWaalsContact O-N 3.14Å; G552-E659 CarbonylContact C-O 3.52Å; G552-E659 WeakPolarHBondContact CA-O 3.44Å
553G95.4Very high91Very high0 Ų056.7 Ų56.70%029%0.292CS..EExtended strand (participates in β ladder)trans147.3-144.6-178.300000111.4C570 E659G553-C570 CarbonylContact C-O 3.54Å; G553-C570 WeakPolarHBondContact CA-O 3.38Å; G553-E659 PolarHBondContact N-O 3.06Å; G553-E659 PolarHBondContact O-N 3.46Å
554V93.4Very high90.5Very high6 Ų655.4 Ų55.44%0.03630%0.295CS..  trans-107.9161.8163.7-68.40000109.6A559 C562 C570 I572 W599 K652V554-A559 HydrophobicContact CB-CB 3.91Å; V554-A559 HydrophobicContact CG2-CB 3.49Å; V554-A559 VanDerWaalsContact CG2-CB 3.49Å; V554-C562 PolarHBondContact O-SG 3.17Å; V554-C570 PolarHBondContact N-O 3.12Å; V554-I572 HydrophobicContact CG1-CD1 4.36Å; V554-W599 PolarHBondContact O-NE1 2.68Å; V554-W599 VanDerWaalsContact O-NE1 3.15Å; V554-K652 WeakPolarHBondContact CG1-O 3.21Å
555M90.4Very high90.5Very high64 Ų6449 Ų4932%0.31529%0.285SS..  trans-117.3163.9-179.6-71.9-67.7-8300110.5H557 T558 A559 W599 E659M555-H557 VanDerWaalsContact CB-CE1 3.47Å; M555-H557 WeakPolarHBondContact CB-CE1 3.25Å; M555-H557 WeakPolarHBondContact CB-ND1 3.24Å; M555-H557 PolarHBondContact O-N 2.73Å; M555-T558 PolarHBondContact N-OG1 2.96Å; M555-T558 PolarHBondContact O-N 2.88Å; M555-T558 PolarHBondContact O-OG1 3.06Å; M555-A559 PolarHBondContact O-N 3.18Å; M555-W599 HydrophobicContact CG-CZ2 4.01Å; M555-W599 HydrophobicContact SD-CD2 4.32Å; M555-W599 HydrophobicContact SD-CZ2 3.95Å; M555-W599 PolarHBondContact SD-NE1 3.08Å; M555-W599 VanDerWaalsContact SD-NE1 3.44Å; M555-E659 WeakPolarHBondContact CB-OE1 3.48Å; M555-E659 VanDerWaalsContact CG-OE2 3.23Å; M555-E659 WeakPolarHBondContact CG-OE2 3.46Å
556K85.6Confident90.5Very high140 Ų14050 Ų5061%0.60928%0.279SS*.THydrogen-bonded Turntrans-51.3-35.4-178.8-175.2-177.6173-171.20113.9T558 A559 P560 C562K556-T558 VanDerWaalsContact C-N 3.28Å; K556-T558 PolarHBondContact O-N 3.1Å; K556-A559 WeakPolarHBondContact CA-O 3.29Å; K556-A559 CarbonylContact O-C 3.6Å; K556-P560 WeakPolarHBondContact O-CA 3.27Å; K556-C562 WeakPolarHBondContact CB-O 3.49Å
557H85.8Confident90.1Very high100 Ų10051.3 Ų51.346%0.46329%0.29SS..THydrogen-bonded Turntrans-71.4-22.9-177.166.8-91.1000113.1M555 E659 Y687M555-H557 VanDerWaalsContact CB-CE1 3.47Å; M555-H557 WeakPolarHBondContact CB-CE1 3.25Å; M555-H557 WeakPolarHBondContact CB-ND1 3.24Å; M555-H557 PolarHBondContact O-N 2.73Å; H557-E659 IonicContact CE1-OE1 3.77Å; H557-E659 PolarHBondContact CE1-OE1 2.98Å; H557-E659 IonicContact CE1-OE2 3.94Å; H557-E659 IonicContact NE2-OE1 2.77Å; H557-E659 PolarHBondContact NE2-OE1 3.33Å; H557-Y687 AromaticContact CD2-CD2 3.83Å; H557-Y687 AromaticContact NE2-CD2 3.27Å; H557-Y687 VanDerWaalsContact NE2-CD2 3.27Å; H557-Y687 WeakPolarHBondContact NE2-CD2 3.39Å; H557-Y687 AromaticContact NE2-CE2 3.33Å; H557-Y687 VanDerWaalsContact NE2-CE2 3.33Å; H557-Y687 WeakPolarHBondContact NE2-CE2 3.49Å
558T86.2Confident89.8Confident37 Ų3753.5 Ų53.523%0.22731%0.314CS..THydrogen-bonded Turntrans-107.5-25.3178460000113.4M555 K556 A654 Y687M555-T558 PolarHBondContact N-OG1 2.96Å; M555-T558 PolarHBondContact O-N 2.88Å; M555-T558 PolarHBondContact O-OG1 3.06Å; K556-T558 VanDerWaalsContact C-N 3.28Å; K556-T558 PolarHBondContact O-N 3.1Å; T558-A654 HydrophobicContact CG2-CB 3.9Å; T558-Y687 HydrophobicContact CG2-CD1 3.66Å; T558-Y687 HydrophobicContact CG2-CD2 3.76Å; T558-Y687 HydrophobicContact CG2-CE1 3.43Å; T558-Y687 VanDerWaalsContact CG2-CE1 3.43Å; T558-Y687 HydrophobicContact CG2-CE2 3.47Å; T558-Y687 VanDerWaalsContact CG2-CE2 3.47Å; T558-Y687 HydrophobicContact CG2-CG 3.84Å
559A87.4Confident89.5Confident22 Ų2255 Ų5518%0.18233%0.326CS..  trans-134.593.2175.400000109.2V554 M555 K556 A561 C562V554-A559 HydrophobicContact CB-CB 3.91Å; V554-A559 HydrophobicContact CG2-CB 3.49Å; V554-A559 VanDerWaalsContact CG2-CB 3.49Å; M555-A559 PolarHBondContact O-N 3.18Å; K556-A559 WeakPolarHBondContact CA-O 3.29Å; K556-A559 CarbonylContact O-C 3.6Å; A559-A561 PolarHBondContact O-N 3.18Å; A559-C562 HydrophobicContact CB-CB 4.18Å; A559-C562 WeakPolarHBondContact O-CB 3.31Å; A559-C562 PolarHBondContact O-N 2.9Å
560P87.8Confident89.4Confident98 Ų9855 Ų5564%0.63633%0.326SS*.THydrogen-bonded Turntrans-57.3-22-175.4-28.836000115.7K556 C562 K563K556-P560 WeakPolarHBondContact O-CA 3.27Å; P560-C562 VanDerWaalsContact C-N 3.34Å; P560-K563 WeakPolarHBondContact O-CE 3.27Å
561A88.8Confident89.3Confident62 Ų6255.6 Ų55.651%0.51233%0.331SS..THydrogen-bonded Turntrans-73.3-24.2174.200000113.2A559 K563 A569A559-A561 PolarHBondContact O-N 3.18Å; A561-K563 PolarHBondContact O-N 2.74Å; A561-A569 HydrophobicContact CB-CB 3.97Å; A561-A569 WeakPolarHBondContact O-CB 3.13Å
562C88.7Confident89.3Confident6 Ų652.4 Ų52.44%0.04132%0.319CS..  trans-67.3112.4174.1167.70000110.1V554 K556 A559 P560 C570V554-C562 PolarHBondContact O-SG 3.17Å; K556-C562 WeakPolarHBondContact CB-O 3.49Å; A559-C562 HydrophobicContact CB-CB 4.18Å; A559-C562 WeakPolarHBondContact O-CB 3.31Å; A559-C562 PolarHBondContact O-N 2.9Å; P560-C562 VanDerWaalsContact C-N 3.34Å; C562-C570 VanDerWaalsContact C-SG 3.59Å; C562-C570 WeakPolarHBondContact CA-SG 3.38Å; C562-C570 HydrophobicContact CB-CB 3.87Å; C562-C570 WeakPolarHBondContact CB-SG 3.2Å; C562-C570 VanDerWaalsContact SG-CA 3.55Å; C562-C570 WeakPolarHBondContact SG-CB 3.37Å; C562-C570 CovalentContact SG-SG 2.03Å; C562-C570 PolarHBondContact SG-SG 3.42Å
563K86.2Confident89.2Confident108 Ų10855.4 Ų55.447%0.4733%0.331SS..BIsolated β-bridgetrans-145.1158.6178.2-62.6179.8-174.61740108.5P560 A561 S565 N566P560-K563 WeakPolarHBondContact O-CE 3.27Å; A561-K563 PolarHBondContact O-N 2.74Å; K563-S565 PolarHBondContact O-N 2.91Å; K563-N566 CarbonylContact O-C 3.6Å; K563-N566 WeakPolarHBondContact O-CA 3.34Å; K563-N566 PolarHBondContact O-N 2.92Å
564S81.5Confident89.2Confident104 Ų10455.4 Ų55.473%0.72733%0.331SS*.THydrogen-bonded Turntrans-56.7-30.4172.252.50000113.1N566 P567S564-N566 VanDerWaalsContact C-N 3.28Å; S564-N566 PolarHBondContact O-N 2.73Å; S564-P567 WeakPolarHBondContact O-CD 3.28Å; S564-P567 WeakPolarHBondContact O-CG 3.32Å
565S86.1Confident89.2Confident104 Ų10455.2 Ų55.273%0.72733%0.329SS*.THydrogen-bonded Turntrans-77.4-9.5173.966.70000114.2K563K563-S565 PolarHBondContact O-N 2.91Å
566N87.5Confident89.2Confident70 Ų7053 Ų5337%0.37432%0.318SS..BIsolated β-bridgetrans-139.167.5175.5-172.26000110.9K563 S564 A568 A569K563-N566 CarbonylContact O-C 3.6Å; K563-N566 WeakPolarHBondContact O-CA 3.34Å; K563-N566 PolarHBondContact O-N 2.92Å; S564-N566 VanDerWaalsContact C-N 3.28Å; S564-N566 PolarHBondContact O-N 2.73Å; N566-A568 PolarHBondContact O-N 3.11Å; N566-A569 HydrophobicContact CB-CB 4.39Å; N566-A569 VanDerWaalsContact ND2-CB 3.32Å; N566-A569 WeakPolarHBondContact ND2-CB 3.25Å; N566-A569 PolarHBondContact O-N 3.01Å; N566-A569 VanDerWaalsContact O-N 3.08Å; N566-A569 PolarHBondContact OD1-N 3.02Å
567P85.4Confident89.3Confident54 Ų5447.1 Ų47.135%0.35129%0.293SS..G310 helixtrans-52.7-37.2179.8-31.540.1000113.9S564 A569 C570 A571 F600S564-P567 WeakPolarHBondContact O-CD 3.28Å; S564-P567 WeakPolarHBondContact O-CG 3.32Å; P567-A569 PolarHBondContact O-N 3.04Å; P567-C570 WeakPolarHBondContact O-CA 3.34Å; P567-C570 VanDerWaalsContact O-CB 3.3Å; P567-C570 WeakPolarHBondContact O-CB 3.37Å; P567-C570 PolarHBondContact O-N 2.88Å; P567-A571 PolarHBondContact O-N 3.13Å; P567-F600 VanDerWaalsContact CA-CE2 3.49Å; P567-F600 HydrophobicContact CB-CD2 3.59Å; P567-F600 HydrophobicContact CB-CE1 4.37Å; P567-F600 HydrophobicContact CB-CE2 3.37Å; P567-F600 HydrophobicContact CB-CG 4.2Å; P567-F600 HydrophobicContact CB-CZ 3.79Å; P567-F600 HydrophobicContact CG-CD1 4.45Å; P567-F600 HydrophobicContact CG-CD2 4.3Å; P567-F600 HydrophobicContact CG-CE1 4.09Å; P567-F600 HydrophobicContact CG-CE2 3.95Å; P567-F600 HydrophobicContact CG-CZ 3.82Å
568A87.6Confident88.8Confident79 Ų7942.4 Ų42.465%0.65327%0.272SS*.G310 helixtrans-61.9-30.4-179.100000113N566 C570 A571N566-A568 PolarHBondContact O-N 3.11Å; A568-C570 PolarHBondContact O-N 3.02Å; A568-A571 PolarHBondContact O-N 3.11Å
569A91.5Very high87.9Confident30 Ų3041 Ų4125%0.24826%0.262CS..G310 helixtrans-75.4-13174.800000113.7A561 N566 P567A561-A569 HydrophobicContact CB-CB 3.97Å; A561-A569 WeakPolarHBondContact O-CB 3.13Å; N566-A569 HydrophobicContact CB-CB 4.39Å; N566-A569 VanDerWaalsContact ND2-CB 3.32Å; N566-A569 WeakPolarHBondContact ND2-CB 3.25Å; N566-A569 PolarHBondContact O-N 3.01Å; N566-A569 VanDerWaalsContact O-N 3.08Å; N566-A569 PolarHBondContact OD1-N 3.02Å; P567-A569 PolarHBondContact O-N 3.04Å
570C93.6Very high86.4Confident4 Ų441.2 Ų41.23%0.02726%0.261CS..THydrogen-bonded Turntrans-90.9-23.9172.4-53.70000112.5G553 V554 C562 P567 A568 F600G553-C570 CarbonylContact C-O 3.54Å; G553-C570 WeakPolarHBondContact CA-O 3.38Å; V554-C570 PolarHBondContact N-O 3.12Å; C562-C570 VanDerWaalsContact C-SG 3.59Å; C562-C570 WeakPolarHBondContact CA-SG 3.38Å; C562-C570 HydrophobicContact CB-CB 3.87Å; C562-C570 WeakPolarHBondContact CB-SG 3.2Å; C562-C570 VanDerWaalsContact SG-CA 3.55Å; C562-C570 WeakPolarHBondContact SG-CB 3.37Å; C562-C570 CovalentContact SG-SG 2.03Å; C562-C570 PolarHBondContact SG-SG 3.42Å; P567-C570 WeakPolarHBondContact O-CA 3.34Å; P567-C570 VanDerWaalsContact O-CB 3.3Å; P567-C570 WeakPolarHBondContact O-CB 3.37Å; P567-C570 PolarHBondContact O-N 2.88Å; A568-C570 PolarHBondContact O-N 3.02Å; C570-F600 HydrophobicContact CB-CE2 4.46Å
571A94.8Very high84.9Confident13 Ų1337.9 Ų37.911%0.10724%0.242CC..  trans-80.5145.2-17200000112.4P567 A568 Y596 L597 N598P567-A571 PolarHBondContact O-N 3.13Å; A568-A571 PolarHBondContact O-N 3.11Å; A571-Y596 HydrophobicContact CB-CD1 4.08Å; A571-Y596 HydrophobicContact CB-CG 4.38Å; A571-L597 WeakPolarHBondContact CA-O 3.12Å; A571-N598 HydrophobicContact CB-CB 3.98Å
572I96.1Very high84Confident0 Ų035.4 Ų35.40%022%0.22CC..EExtended strand (participates in β ladder)trans-110.9124.8174.2-62.5166.5000108V554 Y596 L597 M648 K652 T653 F658V554-I572 HydrophobicContact CG1-CD1 4.36Å; I572-Y596 CarbonylContact O-C 3.34Å; I572-Y596 VanDerWaalsContact O-CA 3.28Å; I572-Y596 WeakPolarHBondContact O-CA 3.29Å; I572-L597 PolarHBondContact N-O 2.89Å; I572-L597 PolarHBondContact O-N 2.75Å; I572-M648 HydrophobicContact CG2-CG 3.47Å; I572-M648 VanDerWaalsContact CG2-CG 3.47Å; I572-M648 HydrophobicContact CG2-SD 4.15Å; I572-K652 HydrophobicContact CB-CB 4.41Å; I572-K652 HydrophobicContact CG1-CB 4.07Å; I572-K652 HydrophobicContact CG2-CB 4.24Å; I572-T653 HydrophobicContact CD1-CG2 4.01Å; I572-F658 HydrophobicContact CD1-CB 3.41Å; I572-F658 VanDerWaalsContact CD1-CB 3.41Å; I572-F658 HydrophobicContact CD1-CG 4.4Å
573R94.4Very high83.3Confident63 Ų6341.4 Ų41.424%0.23825%0.248CC..EExtended strand (participates in β ladder)trans-67135.8176.9-172.2169.2-179.2162.95.5110.8F531 N595 Y596 D649F531-R573 HydrophobicContact CE1-CG 4.31Å; F531-R573 HydrophobicContact CZ-CB 4.18Å; F531-R573 HydrophobicContact CZ-CG 3.93Å; R573-N595 WeakPolarHBondContact CA-O 3.49Å; R573-Y596 HydrophobicContact CB-CD1 4.04Å; R573-Y596 HydrophobicContact CB-CE1 3.88Å; R573-Y596 HydrophobicContact CG-CD1 4.47Å; R573-Y596 HydrophobicContact CG-CE1 4.12Å; R573-D649 HydrophobicContact CB-CB 4.3Å; R573-D649 PolarHBondContact O-N 3.18Å
574I94.2Very high83.3Confident0 Ų037.8 Ų37.80%023%0.234CC..EExtended strand (participates in β ladder)trans-128.1160.2178.560.8173.4000110.7N595 L597 F644 V646 M647 M648I574-N595 WeakPolarHBondContact CG1-O 3.45Å; I574-N595 PolarHBondContact N-O 2.03Å; I574-L597 HydrophobicContact CG2-CB 4.15Å; I574-F644 HydrophobicContact CD1-CE2 3.91Å; I574-F644 HydrophobicContact CD1-CZ 3.69Å; I574-F644 HydrophobicContact CG2-CZ 4.26Å; I574-V646 HydrophobicContact CB-CB 4.09Å; I574-V646 HydrophobicContact CB-CG1 4.24Å; I574-V646 HydrophobicContact CB-CG2 4.23Å; I574-V646 HydrophobicContact CD1-CG1 4.24Å; I574-V646 HydrophobicContact CG2-CB 4.39Å; I574-V646 HydrophobicContact CG2-CG2 3.96Å; I574-M647 CarbonylContact C-O 3.44Å; I574-M647 VanDerWaalsContact CA-O 3.23Å; I574-M647 WeakPolarHBondContact CA-O 3.44Å; I574-M648 HydrophobicContact CG2-CE 4.49Å; I574-M648 HydrophobicContact CG2-CG 4.47Å
575V92.5Very high83.6Confident2 Ų239.6 Ų39.61%0.01223%0.229CC..EExtended strand (participates in β ladder)trans-131.9123.9162.4-1790000107.5Q492 I525 L527 F531 V577 V646 M647Q492-V575 WeakPolarHBondContact O-CG2 3.13Å; I525-V575 HydrophobicContact CD1-CG1 3.71Å; I525-V575 HydrophobicContact CD1-CG2 4.49Å; L527-V575 HydrophobicContact CD1-CB 4.49Å; L527-V575 HydrophobicContact CD1-CG2 4.12Å; L527-V575 HydrophobicContact CD2-CG2 3.96Å; F531-V575 HydrophobicContact CE1-CG2 4.27Å; V575-V577 PolarHBondContact O-N 3.12Å; V575-V646 CarbonylContact O-C 3.55Å; V575-V646 VanDerWaalsContact O-CA 3.23Å; V575-V646 WeakPolarHBondContact O-CA 3.35Å; V575-V646 WeakPolarHBondContact O-CB 3.45Å; V575-M647 HydrophobicContact CB-CB 4.22Å; V575-M647 PolarHBondContact N-O 2.84Å; V575-M647 PolarHBondContact O-N 3.16Å
576R91.2Very high83.8Confident18 Ų1834.9 Ų34.97%0.06820%0.195CC..EExtended strand (participates in β ladder)trans-60.1130.8178.4-70-53.6-162.9126.9-2.3112S498 D578 D594 P618S498-R576 VanDerWaalsContact CB-O 3.27Å; S498-R576 WeakPolarHBondContact CB-O 3.4Å; S498-R576 PolarHBondContact OG-O 3.29Å; R576-D578 VanDerWaalsContact CB-OD1 3.25Å; R576-D578 WeakPolarHBondContact CB-OD1 3.04Å; R576-D578 WeakPolarHBondContact CD-OD1 3.23Å; R576-D578 IonicContact CZ-OD2 3.81Å; R576-D578 IonicContact NH1-OD1 2.68Å; R576-D578 IonicContact NH1-OD2 3.49Å; R576-D578 PolarHBondContact NH1-OD2 2.83Å; R576-D594 IonicContact CZ-OD2 3.51Å; R576-D594 IonicContact NE-OD2 3.66Å; R576-D594 PolarHBondContact NE-OD2 2.86Å; R576-D594 IonicContact NH2-OD2 3.6Å; R576-D594 PolarHBondContact NH2-OD2 2.9Å; R576-P618 PolarHBondContact NH1-O 3.5Å; R576-P618 PolarHBondContact NH2-O 3.01Å
577V88.9Confident84.1Confident15 Ų1531.6 Ų31.69%0.09118%0.178CC..  trans-114.3-21.6174.4179.60000111.2V500 V575 D645 M647V500-V577 HydrophobicContact CG2-CG1 3.99Å; V500-V577 HydrophobicContact CG2-CG2 4.2Å; V575-V577 PolarHBondContact O-N 3.12Å; V577-D645 PolarHBondContact N-O 3.47Å; V577-M647 HydrophobicContact CG2-CG 3.62Å; V577-M647 HydrophobicContact CG2-SD 4.25Å
578D74.6Confident84.2Confident2 Ų232.4 Ų32.41%0.01118%0.176CC..SBendtrans-52.7154.31723020.8000113.3R576 T580 F587 M643 D645R576-D578 VanDerWaalsContact CB-OD1 3.25Å; R576-D578 WeakPolarHBondContact CB-OD1 3.04Å; R576-D578 WeakPolarHBondContact CD-OD1 3.23Å; R576-D578 IonicContact CZ-OD2 3.81Å; R576-D578 IonicContact NH1-OD1 2.68Å; R576-D578 IonicContact NH1-OD2 3.49Å; R576-D578 PolarHBondContact NH1-OD2 2.83Å; D578-T580 PolarHBondContact O-N 3.4Å; D578-T580 VanDerWaalsContact O-N 3.12Å; D578-F587 HydrophobicContact CB-CZ 4.01Å; D578-F587 WeakPolarHBondContact OD2-CZ 3.4Å; D578-M643 HydrophobicContact CB-CE 4.31Å; D578-D645 HydrophobicContact CB-CB 3.91Å; D578-D645 PolarHBondContact N-O 3.26Å
579E66.6Low84.3Confident8 Ų831.7 Ų31.74%0.03716%0.159CC..  trans-79.6101.4-171.6-174.4168.2-129.300111.5K497 F510 R512 A581 T582K497-E579 HydrophobicContact CD-CG 4.31Å; K497-E579 IonicContact NZ-OE1 3.84Å; K497-E579 PolarHBondContact NZ-OE1 3.12Å; F510-E579 WeakPolarHBondContact CE1-OE2 3.13Å; R512-E579 IonicContact CZ-OE2 3.51Å; R512-E579 IonicContact NE-OE1 3.15Å; R512-E579 IonicContact NE-OE2 2.62Å; R512-E579 PolarHBondContact NE-OE2 3.17Å; R512-E579 IonicContact NH2-OE2 3.03Å; R512-E579 PolarHBondContact NH2-OE2 3.12Å; E579-A581 HydrophobicContact CG-CB 3.7Å; E579-A581 PolarHBondContact O-N 3.17Å; E579-A581 VanDerWaalsContact O-N 3.09Å; E579-T582 PolarHBondContact O-N 2.7Å
580T57Low84.4Confident26 Ų2631 Ų3116%0.1615%0.15CC..THydrogen-bonded Turntrans-64.6-7.1168.963.80000112.8G496 K497 D578 T582 K588G496-T580 WeakPolarHBondContact CA-OG1 3.36Å; K497-T580 PolarHBondContact N-OG1 3.47Å; K497-T580 VanDerWaalsContact N-OG1 3.14Å; D578-T580 PolarHBondContact O-N 3.4Å; D578-T580 VanDerWaalsContact O-N 3.12Å; T580-T582 PolarHBondContact O-N 3.36Å; T580-K588 WeakPolarHBondContact O-CE 3.38Å; T580-K588 VanDerWaalsContact O-CG 3.31Å; T580-K588 WeakPolarHBondContact O-CG 3.46Å
581A56.3Low84.3Confident27 Ų2731.4 Ų31.422%0.22315%0.153CC..THydrogen-bonded Turntrans-81.37.1173.900000114.3T486 E579T486-A581 HydrophobicContact CG2-CB 4.4Å; E579-A581 HydrophobicContact CG-CB 3.7Å; E579-A581 PolarHBondContact O-N 3.17Å; E579-A581 VanDerWaalsContact O-N 3.09Å
582T69.7Low84Confident10 Ų1035.3 Ų35.36%0.06117%0.168CC..SBendtrans-58.7154.6174.5-179.80000113.2E579 T580 D584 F587 K588 L620E579-T582 PolarHBondContact O-N 2.7Å; T580-T582 PolarHBondContact O-N 3.36Å; T582-D584 HydrophobicContact CG2-CB 3.94Å; T582-D584 PolarHBondContact O-N 3.06Å; T582-D584 PolarHBondContact OG1-N 3.07Å; T582-D584 VanDerWaalsContact OG1-N 3.16Å; T582-F587 HydrophobicContact CG2-CD1 3.61Å; T582-F587 HydrophobicContact CG2-CE1 4.26Å; T582-F587 HydrophobicContact CG2-CG 4.46Å; T582-K588 HydrophobicContact CG2-CG 4.04Å; T582-K588 WeakPolarHBondContact O-CD 3.01Å; T582-K588 WeakPolarHBondContact O-CE 3.34Å; T582-K588 PolarHBondContact O-NZ 3.14Å; T582-L620 HydrophobicContact CG2-CD1 3.92Å
583E73.1Confident83.6Confident132 Ų13239.2 Ų39.262%0.61719%0.188SC*.SBendtrans-74.3-10.6169.9-70.2-173.5-176.700112.7K585 K629E583-K585 PolarHBondContact O-N 3.45Å; E583-K629 IonicContact OE1-NZ 3.18Å; E583-K629 PolarHBondContact OE1-NZ 2.72Å; E583-K629 VanDerWaalsContact OE2-CD 3.25Å; E583-K629 WeakPolarHBondContact OE2-CD 3.49Å; E583-K629 IonicContact OE2-NZ 3.21Å; E583-K629 PolarHBondContact OE2-NZ 3.28Å
584D86Confident83.5Confident33 Ų3336.4 Ų36.418%0.17618%0.178CC..  trans-70.797.1176.7-171.3-20.1000111.2T582 A586 F587 K588T582-D584 HydrophobicContact CG2-CB 3.94Å; T582-D584 PolarHBondContact O-N 3.06Å; T582-D584 PolarHBondContact OG1-N 3.07Å; T582-D584 VanDerWaalsContact OG1-N 3.16Å; D584-A586 VanDerWaalsContact C-N 3.33Å; D584-A586 PolarHBondContact OD1-N 3.18Å; D584-A586 VanDerWaalsContact OD1-N 3.08Å; D584-F587 HydrophobicContact CB-CB 3.91Å; D584-F587 VanDerWaalsContact CG-CB 3.43Å; D584-F587 PolarHBondContact OD1-N 2.75Å; D584-K588 WeakPolarHBondContact O-CG 3.12Å; D584-K588 PolarHBondContact O-N 3.13Å; D584-K588 VanDerWaalsContact O-N 3.12Å
585K88.3Confident83.4Confident142 Ų14237.8 Ų37.862%0.61719%0.186SC*.Hα-helixtrans-64.8-36.7179.7-62.6-176.7-179.1-179.60112.3E583 K588 E589 Y609E583-K585 PolarHBondContact O-N 3.45Å; K585-K588 WeakPolarHBondContact O-CB 3.31Å; K585-K588 PolarHBondContact O-N 2.94Å; K585-E589 WeakPolarHBondContact O-CG 3.45Å; K585-E589 PolarHBondContact O-N 2.93Å; K585-Y609 HydrophobicContact CB-CD2 4.35Å; K585-Y609 HydrophobicContact CB-CE2 3.59Å
586A91.6Very high83.5Confident4 Ų442 Ų423%0.03320%0.202CC..Hα-helixtrans-68.4-46.4-177.900000110.4D584 K588 E589 W590 Y609D584-A586 VanDerWaalsContact C-N 3.33Å; D584-A586 PolarHBondContact OD1-N 3.18Å; D584-A586 VanDerWaalsContact OD1-N 3.08Å; A586-K588 VanDerWaalsContact C-N 3.34Å; A586-K588 PolarHBondContact O-N 3.05Å; A586-E589 PolarHBondContact O-N 3.38Å; A586-W590 HydrophobicContact CB-CD2 4.48Å; A586-W590 HydrophobicContact CB-CE3 3.85Å; A586-W590 HydrophobicContact CB-CH2 3.87Å; A586-W590 HydrophobicContact CB-CZ2 4.49Å; A586-W590 HydrophobicContact CB-CZ3 3.51Å; A586-W590 WeakPolarHBondContact O-CB 3.3Å; A586-W590 PolarHBondContact O-N 2.82Å; A586-Y609 HydrophobicContact CB-CD1 3.63Å; A586-Y609 HydrophobicContact CB-CD2 4.25Å; A586-Y609 HydrophobicContact CB-CE1 3.97Å; A586-Y609 HydrophobicContact CB-CG 3.8Å
587F91.9Very high83.7Confident1 Ų141.1 Ų41.10%0.00420%0.199CC..Hα-helixtrans-56-46.8172.5174.4-92.2000112.1D578 T582 D584 S591 P618 L620D578-F587 HydrophobicContact CB-CZ 4.01Å; D578-F587 WeakPolarHBondContact OD2-CZ 3.4Å; T582-F587 HydrophobicContact CG2-CD1 3.61Å; T582-F587 HydrophobicContact CG2-CE1 4.26Å; T582-F587 HydrophobicContact CG2-CG 4.46Å; D584-F587 HydrophobicContact CB-CB 3.91Å; D584-F587 VanDerWaalsContact CG-CB 3.43Å; D584-F587 PolarHBondContact OD1-N 2.75Å; F587-S591 WeakPolarHBondContact O-CB 3.24Å; F587-S591 PolarHBondContact O-N 3.1Å; F587-S591 PolarHBondContact O-OG 2.95Å; F587-P618 HydrophobicContact CD2-CB 4.1Å; F587-P618 HydrophobicContact CD2-CG 4.39Å; F587-L620 HydrophobicContact CD1-CD1 4.08Å; F587-L620 HydrophobicContact CD2-CB 4.09Å; F587-L620 HydrophobicContact CD2-CD1 4.46Å; F587-L620 HydrophobicContact CE1-CD1 4.29Å; F587-L620 HydrophobicContact CE2-CB 3.75Å; F587-L620 HydrophobicContact CG-CD1 4.17Å; F587-L620 HydrophobicContact CZ-CB 3.99Å
588K88.4Confident84Confident72 Ų7241.1 Ų41.131%0.31320%0.198SC..Hα-helixtrans-56.9-51.8178.4-81.8167.4153.6170.30112.5T580 T582 D584 K585 A586 S591T580-K588 WeakPolarHBondContact O-CE 3.38Å; T580-K588 VanDerWaalsContact O-CG 3.31Å; T580-K588 WeakPolarHBondContact O-CG 3.46Å; T582-K588 HydrophobicContact CG2-CG 4.04Å; T582-K588 WeakPolarHBondContact O-CD 3.01Å; T582-K588 WeakPolarHBondContact O-CE 3.34Å; T582-K588 PolarHBondContact O-NZ 3.14Å; D584-K588 WeakPolarHBondContact O-CG 3.12Å; D584-K588 PolarHBondContact O-N 3.13Å; D584-K588 VanDerWaalsContact O-N 3.12Å; K585-K588 WeakPolarHBondContact O-CB 3.31Å; K585-K588 PolarHBondContact O-N 2.94Å; A586-K588 VanDerWaalsContact C-N 3.34Å; A586-K588 PolarHBondContact O-N 3.05Å; K588-S591 PolarHBondContact O-N 3.1Å
589E90.6Very high84.8Confident64 Ų6443.2 Ų43.230%0.29921%0.206SC..Hα-helixtrans-67.9-46.7-176.6-69.2-55.3128.500111.5K585 A586 S591 K592 G607 Y609K585-E589 WeakPolarHBondContact O-CG 3.45Å; K585-E589 PolarHBondContact O-N 2.93Å; A586-E589 PolarHBondContact O-N 3.38Å; E589-S591 VanDerWaalsContact C-N 3.26Å; E589-S591 PolarHBondContact O-N 2.86Å; E589-K592 WeakPolarHBondContact O-CB 3.22Å; E589-K592 PolarHBondContact O-N 2.94Å; E589-K592 WeakPolarHBondContact OE1-CE 3.46Å; E589-K592 IonicContact OE1-NZ 2.73Å; E589-K592 PolarHBondContact OE1-NZ 2.96Å; E589-K592 WeakPolarHBondContact OE2-CE 3.22Å; E589-K592 IonicContact OE2-NZ 3.75Å; E589-K592 PolarHBondContact OE2-NZ 3.46Å; E589-G607 CarbonylContact O-C 3.53Å; E589-G607 VanDerWaalsContact O-CA 3.3Å; E589-G607 WeakPolarHBondContact O-CA 3.18Å; E589-Y609 HydrophobicContact CB-CD2 4.17Å; E589-Y609 HydrophobicContact CG-CD2 3.95Å
590W93.1Very high85.8Confident15 Ų1547.9 Ų47.96%0.05723%0.226CC..Hα-helixtrans-67.9-21.6177.7-68.6-37000114.4H547 F549 A586 K592 Q606 Y609 K612 A614 P618H547-W590 HydrophobicContact CB-CZ3 4.06Å; H547-W590 AromaticContact CD2-CH2 3.88Å; H547-W590 AromaticContact CD2-CZ3 3.85Å; H547-W590 AromaticContact CG-CZ3 3.69Å; H547-W590 AromaticContact ND1-CZ3 3.97Å; F549-W590 HydrophobicContact CE1-CD2 4.19Å; F549-W590 AromaticContact CE1-CE3 3.85Å; F549-W590 HydrophobicContact CE1-CE3 3.85Å; F549-W590 HydrophobicContact CE1-CZ3 4.19Å; F549-W590 HydrophobicContact CZ-CD2 4.23Å; F549-W590 AromaticContact CZ-CE3 3.71Å; F549-W590 HydrophobicContact CZ-CE3 3.71Å; F549-W590 AromaticContact CZ-CH2 3.96Å; F549-W590 HydrophobicContact CZ-CH2 3.96Å; F549-W590 HydrophobicContact CZ-CZ2 4.45Å; F549-W590 AromaticContact CZ-CZ3 3.56Å; F549-W590 HydrophobicContact CZ-CZ3 3.56Å; A586-W590 HydrophobicContact CB-CD2 4.48Å; A586-W590 HydrophobicContact CB-CE3 3.85Å; A586-W590 HydrophobicContact CB-CH2 3.87Å; A586-W590 HydrophobicContact CB-CZ2 4.49Å; A586-W590 HydrophobicContact CB-CZ3 3.51Å; A586-W590 WeakPolarHBondContact O-CB 3.3Å; A586-W590 PolarHBondContact O-N 2.82Å; W590-K592 VanDerWaalsContact C-N 3.32Å; W590-Q606 WeakPolarHBondContact O-CG 3.49Å; W590-Q606 PolarHBondContact O-NE2 3.29Å; W590-Y609 HydrophobicContact CZ2-CD1 4.49Å; W590-K612 PolarHBondContact NE1-O 2.84Å; W590-A614 HydrophobicContact CB-CB 4.11Å; W590-A614 HydrophobicContact CD2-CB 4.49Å; W590-A614 HydrophobicContact CG-CB 3.91Å; W590-P618 HydrophobicContact CB-CB 4.16Å; W590-P618 HydrophobicContact CB-CG 3.72Å; W590-P618 HydrophobicContact CE3-CB 4.39Å
591S91Very high87Confident12 Ų1246.7 Ų46.78%0.08422%0.219CC..Hα-helixtrans-78.9-16.1176.4-61.90000112.8F587 K588 E589 N593 D594F587-S591 WeakPolarHBondContact O-CB 3.24Å; F587-S591 PolarHBondContact O-N 3.1Å; F587-S591 PolarHBondContact O-OG 2.95Å; K588-S591 PolarHBondContact O-N 3.1Å; E589-S591 VanDerWaalsContact C-N 3.26Å; E589-S591 PolarHBondContact O-N 2.86Å; S591-N593 PolarHBondContact O-N 3.1Å; S591-D594 PolarHBondContact O-N 2.65Å
592K88.2Confident88.6Confident96 Ų9647.7 Ų47.742%0.41722%0.222SC..THydrogen-bonded Turntrans-59.8125.6174.5-66.5177.3-177.8170.60108.9E589 W590 D594 Q606 G607E589-K592 WeakPolarHBondContact O-CB 3.22Å; E589-K592 PolarHBondContact O-N 2.94Å; E589-K592 WeakPolarHBondContact OE1-CE 3.46Å; E589-K592 IonicContact OE1-NZ 2.73Å; E589-K592 PolarHBondContact OE1-NZ 2.96Å; E589-K592 WeakPolarHBondContact OE2-CE 3.22Å; E589-K592 IonicContact OE2-NZ 3.75Å; E589-K592 PolarHBondContact OE2-NZ 3.46Å; W590-K592 VanDerWaalsContact C-N 3.32Å; K592-D594 PolarHBondContact O-N 3.05Å; K592-Q606 CarbonylContact O-C 3.54Å; K592-Q606 WeakPolarHBondContact O-CA 3.24Å; K592-G607 PolarHBondContact O-N 3.42Å
593N88.5Confident89.7Confident81 Ų8148 Ų4843%0.43322%0.223SC..THydrogen-bonded Turntrans55.824.9-179.1-52-44.1000115.3S591 N595 T605S591-N593 PolarHBondContact O-N 3.1Å; N593-N595 PolarHBondContact O-N 2.95Å; N593-N595 PolarHBondContact O-ND2 2.68Å; N593-T605 VanDerWaalsContact CB-O 3.22Å; N593-T605 WeakPolarHBondContact CB-O 2.99Å; N593-T605 PolarHBondContact ND2-O 2.79Å
594D91.7Very high90.4Very high4 Ų448.4 Ų48.42%0.02124%0.237CC..  trans-78.896165.1179.448.7000108.9R576 S591 K592 Q606 S617R576-D594 IonicContact CZ-OD2 3.51Å; R576-D594 IonicContact NE-OD2 3.66Å; R576-D594 PolarHBondContact NE-OD2 2.86Å; R576-D594 IonicContact NH2-OD2 3.6Å; R576-D594 PolarHBondContact NH2-OD2 2.9Å; S591-D594 PolarHBondContact O-N 2.65Å; K592-D594 PolarHBondContact O-N 3.05Å; D594-Q606 HydrophobicContact CB-CG 4.29Å; D594-S617 PolarHBondContact OD1-OG 3.36Å; D594-S617 VanDerWaalsContact OD2-CB 3.26Å; D594-S617 WeakPolarHBondContact OD2-CB 3.49Å; D594-S617 PolarHBondContact OD2-OG 3.06Å
595N91.6Very high90.5Very high30 Ų3051.2 Ų51.216%0.1626%0.256CS..  trans-110.2-9.7-170.1-65.1-69.3000113.3S493 R573 I574 N593 E603S493-N595 PolarHBondContact OG-OD1 3.39Å; S493-N595 VanDerWaalsContact OG-OD1 3.04Å; R573-N595 WeakPolarHBondContact CA-O 3.49Å; I574-N595 WeakPolarHBondContact CG1-O 3.45Å; I574-N595 PolarHBondContact N-O 2.03Å; N593-N595 PolarHBondContact O-N 2.95Å; N593-N595 PolarHBondContact O-ND2 2.68Å; N595-E603 PolarHBondContact N-OE1 2.8Å; N595-E603 PolarHBondContact N-OE2 2.9Å
596Y94.6Very high90.6Very high90 Ų9045 Ų4535%0.35323%0.229SC..EExtended strand (participates in β ladder)trans-141.4129.4-177.7-59.7-90.2000112.7A571 I572 R573 N598 E603A571-Y596 HydrophobicContact CB-CD1 4.08Å; A571-Y596 HydrophobicContact CB-CG 4.38Å; I572-Y596 CarbonylContact O-C 3.34Å; I572-Y596 VanDerWaalsContact O-CA 3.28Å; I572-Y596 WeakPolarHBondContact O-CA 3.29Å; R573-Y596 HydrophobicContact CB-CD1 4.04Å; R573-Y596 HydrophobicContact CB-CE1 3.88Å; R573-Y596 HydrophobicContact CG-CD1 4.47Å; R573-Y596 HydrophobicContact CG-CE1 4.12Å; Y596-N598 PolarHBondContact O-N 3.33Å; Y596-N598 VanDerWaalsContact O-N 3.14Å; Y596-N598 PolarHBondContact O-ND2 3.02Å; Y596-N598 VanDerWaalsContact O-ND2 3.12Å; Y596-E603 WeakPolarHBondContact CD2-OE2 3.35Å; Y596-E603 PolarHBondContact N-OE1 2.83Å
597L96.4Very high90.6Very high0 Ų045.4 Ų45.40%023%0.233CC..EExtended strand (participates in β ladder)trans-69.9110.7156.3-178.367000107.7L550 G552 A571 I572 I574 M648 F658L550-L597 HydrophobicContact CB-CD1 3.95Å; G552-L597 CarbonylContact O-C 3.55Å; G552-L597 VanDerWaalsContact O-C 3.32Å; A571-L597 WeakPolarHBondContact CA-O 3.12Å; I572-L597 PolarHBondContact N-O 2.89Å; I572-L597 PolarHBondContact O-N 2.75Å; I574-L597 HydrophobicContact CG2-CB 4.15Å; L597-M648 HydrophobicContact CD2-CE 4.03Å; L597-F658 HydrophobicContact CD2-CD2 3.7Å; L597-F658 HydrophobicContact CD2-CE2 4.05Å
598N94.2Very high90.7Very high15 Ų1550 Ų508%0.0826%0.255CS..  trans-137.5155.7-173.280.282.6000112.4R551 G552 A571 Y596 F600 G601R551-N598 WeakPolarHBondContact CA-O 3.49Å; G552-N598 PolarHBondContact N-O 3.35Å; G552-N598 VanDerWaalsContact N-O 3.09Å; G552-N598 CarbonylContact O-C 3.53Å; G552-N598 WeakPolarHBondContact O-CA 3.36Å; G552-N598 PolarHBondContact O-N 2.86Å; G552-N598 VanDerWaalsContact O-N 3.16Å; A571-N598 HydrophobicContact CB-CB 3.98Å; Y596-N598 PolarHBondContact O-N 3.33Å; Y596-N598 VanDerWaalsContact O-N 3.14Å; Y596-N598 PolarHBondContact O-ND2 3.02Å; Y596-N598 VanDerWaalsContact O-ND2 3.12Å; N598-F600 PolarHBondContact OD1-N 3.05Å; N598-G601 PolarHBondContact ND2-O 2.92Å; N598-G601 PolarHBondContact OD1-N 2.99Å; N598-G601 VanDerWaalsContact OD1-N 3.09Å; N598-G601 PolarHBondContact OD1-O 2.77Å
599W92.8Very high90.9Very high45 Ų4549.2 Ų49.217%0.1725%0.251CS..SBendtrans-82.4-14.1-178.4-70.5113.1000114.5R551 G552 V554 M555 E659 K661 N691R551-W599 HydrophobicContact CB-CE3 4.17Å; G552-W599 PolarHBondContact O-N 2.78Å; G552-W599 VanDerWaalsContact O-N 3.14Å; V554-W599 PolarHBondContact O-NE1 2.68Å; V554-W599 VanDerWaalsContact O-NE1 3.15Å; M555-W599 HydrophobicContact CG-CZ2 4.01Å; M555-W599 HydrophobicContact SD-CD2 4.32Å; M555-W599 HydrophobicContact SD-CZ2 3.95Å; M555-W599 PolarHBondContact SD-NE1 3.08Å; M555-W599 VanDerWaalsContact SD-NE1 3.44Å; W599-E659 HydrophobicContact CH2-CB 4.12Å; W599-E659 HydrophobicContact CZ2-CB 3.61Å; W599-K661 HydrophobicContact CZ3-CB 4.49Å; W599-K661 HydrophobicContact CZ3-CG 4.23Å; W599-N691 HydrophobicContact CH2-CB 3.98Å; W599-N691 VanDerWaalsContact CH2-CG 3.44Å; W599-N691 WeakPolarHBondContact CH2-ND2 3.4Å
600F87.2Confident91Very high106 Ų10652.4 Ų52.447%0.46527%0.265SS..SBendtrans-96.22.1-168.2-59.4-90.9000112.6P567 C570 N598P567-F600 VanDerWaalsContact CA-CE2 3.49Å; P567-F600 HydrophobicContact CB-CD2 3.59Å; P567-F600 HydrophobicContact CB-CE1 4.37Å; P567-F600 HydrophobicContact CB-CE2 3.37Å; P567-F600 HydrophobicContact CB-CG 4.2Å; P567-F600 HydrophobicContact CB-CZ 3.79Å; P567-F600 HydrophobicContact CG-CD1 4.45Å; P567-F600 HydrophobicContact CG-CD2 4.3Å; P567-F600 HydrophobicContact CG-CE1 4.09Å; P567-F600 HydrophobicContact CG-CE2 3.95Å; P567-F600 HydrophobicContact CG-CZ 3.82Å; C570-F600 HydrophobicContact CB-CE2 4.46Å; N598-F600 PolarHBondContact OD1-N 3.05Å
601G82.4Confident90.9Very high1 Ų159 Ų591%0.0130%0.302CS..  trans90.8-126.4175.700000111.4N598 I615N598-G601 PolarHBondContact ND2-O 2.92Å; N598-G601 PolarHBondContact OD1-N 2.99Å; N598-G601 VanDerWaalsContact OD1-N 3.09Å; N598-G601 PolarHBondContact OD1-O 2.77Å; G601-I615 WeakPolarHBondContact CA-O 3.06Å
602T90.2Very high91Very high48 Ų4864.9 Ų64.929%0.29433%0.326SS..SBendtrans-69136.5-175.6-75.90000113.1Q606 A614T602-Q606 HydrophobicContact CG2-CB 4.16Å; T602-A614 WeakPolarHBondContact OG1-CA 3.31Å; T602-A614 WeakPolarHBondContact OG1-CB 3.28Å; T602-A614 PolarHBondContact OG1-N 2.98Å; T602-A614 PolarHBondContact OG1-O 3.34Å
603E91Very high91.3Very high18 Ų1863.2 Ų63.28%0.08433%0.326CS..  trans-78.3148.3170.7-55176-144.200111.3N595 Y596 T605 Q606N595-E603 PolarHBondContact N-OE1 2.8Å; N595-E603 PolarHBondContact N-OE2 2.9Å; Y596-E603 WeakPolarHBondContact CD2-OE2 3.35Å; Y596-E603 PolarHBondContact N-OE1 2.83Å; E603-T605 PolarHBondContact O-N 2.74Å; E603-Q606 HydrophobicContact CB-CB 4.04Å; E603-Q606 VanDerWaalsContact N-OE1 3.13Å; E603-Q606 WeakPolarHBondContact O-CB 3.36Å; E603-Q606 PolarHBondContact O-N 2.93Å
604P87.9Confident91.6Very high140 Ų14059.6 Ų59.691%0.90931%0.308SS*.THydrogen-bonded Turntrans-55.3-25.3-175.2-28.335.4000116
605T88Confident91.7Very high92 Ų9261.1 Ų61.156%0.56432%0.315SS*.THydrogen-bonded Turntrans-112.64.6-179.258.20000113.4N593 E603N593-T605 VanDerWaalsContact CB-O 3.22Å; N593-T605 WeakPolarHBondContact CB-O 2.99Å; N593-T605 PolarHBondContact ND2-O 2.79Å; E603-T605 PolarHBondContact O-N 2.74Å
606Q91.9Very high91.9Very high10 Ų1059.7 Ų59.75%0.04731%0.308CS..  trans-67.1142.7179-173.1177.25.200110W590 K592 D594 T602 E603 G616W590-Q606 WeakPolarHBondContact O-CG 3.49Å; W590-Q606 PolarHBondContact O-NE2 3.29Å; K592-Q606 CarbonylContact O-C 3.54Å; K592-Q606 WeakPolarHBondContact O-CA 3.24Å; D594-Q606 HydrophobicContact CB-CG 4.29Å; T602-Q606 HydrophobicContact CG2-CB 4.16Å; E603-Q606 HydrophobicContact CB-CB 4.04Å; E603-Q606 VanDerWaalsContact N-OE1 3.13Å; E603-Q606 WeakPolarHBondContact O-CB 3.36Å; E603-Q606 PolarHBondContact O-N 2.93Å; Q606-G616 PolarHBondContact NE2-O 2.97Å
607G90.4Very high91.9Very high13 Ų1355.4 Ų55.413%0.13429%0.291CS..  trans-65.3160.1-176.500000113.4E589 K592E589-G607 CarbonylContact O-C 3.53Å; E589-G607 VanDerWaalsContact O-CA 3.3Å; E589-G607 WeakPolarHBondContact O-CA 3.18Å; K592-G607 PolarHBondContact O-N 3.42Å
608E94.1Very high91.8Very high97 Ų9755.5 Ų55.545%0.45329%0.292SS..EExtended strand (participates in β ladder)trans-120.8148.6179.9-57.2-164.4144.600110.5S613E608-S613 PolarHBondContact OE1-OG 3.15Å
609Y93Very high91.9Very high57 Ų5754.9 Ų54.922%0.22429%0.288CS..EExtended strand (participates in β ladder)trans-118.6123.7175.2-179.7-103.6000109.1K585 A586 E589 W590 N611 K612K585-Y609 HydrophobicContact CB-CD2 4.35Å; K585-Y609 HydrophobicContact CB-CE2 3.59Å; A586-Y609 HydrophobicContact CB-CD1 3.63Å; A586-Y609 HydrophobicContact CB-CD2 4.25Å; A586-Y609 HydrophobicContact CB-CE1 3.97Å; A586-Y609 HydrophobicContact CB-CG 3.8Å; E589-Y609 HydrophobicContact CB-CD2 4.17Å; E589-Y609 HydrophobicContact CG-CD2 3.95Å; W590-Y609 HydrophobicContact CZ2-CD1 4.49Å; Y609-N611 VanDerWaalsContact C-N 3.26Å; Y609-N611 PolarHBondContact O-N 3.27Å; Y609-K612 PolarHBondContact N-O 3.32Å; Y609-K612 VanDerWaalsContact N-O 3.09Å; Y609-K612 WeakPolarHBondContact O-CB 3.36Å; Y609-K612 PolarHBondContact O-N 3.06Å
610E91.8Very high91.9Very high131 Ų13152.9 Ų52.961%0.61228%0.281SS*.THydrogen-bonded Turntrans51.241.8-178.1-63.9177.1-176.100113.5K612E610-K612 PolarHBondContact O-N 3.3Å
611N91.8Very high92.2Very high154 Ų15451.1 Ų51.182%0.82427%0.271SS*.THydrogen-bonded Turntrans60.719.2-175.2-51.4-46.7000114.7Y609Y609-N611 VanDerWaalsContact C-N 3.26Å; Y609-N611 PolarHBondContact O-N 3.27Å
612K93.3Very high92.7Very high135 Ų13551.1 Ų51.159%0.58727%0.271SS*.EExtended strand (participates in β ladder)trans-105.1119.6170.8-62.9178.3-177171.10108.9W590 Y609 E610W590-K612 PolarHBondContact NE1-O 2.84Å; Y609-K612 PolarHBondContact N-O 3.32Å; Y609-K612 VanDerWaalsContact N-O 3.09Å; Y609-K612 WeakPolarHBondContact O-CB 3.36Å; Y609-K612 PolarHBondContact O-N 3.06Å; E610-K612 PolarHBondContact O-N 3.3Å
613S94.6Very high92.6Very high60 Ų6048.9 Ų48.942%0.4226%0.257SS..EExtended strand (participates in β ladder)trans-63152.2166.1-39.60000110E608E608-S613 PolarHBondContact OE1-OG 3.15Å
614A94.1Very high92.6Very high6 Ų651.2 Ų51.25%0.0527%0.271CS..  trans-60.6175.5169.400000111F549 W590 T602 G616F549-A614 HydrophobicContact CD1-CB 4.34Å; F549-A614 HydrophobicContact CE1-CB 3.83Å; W590-A614 HydrophobicContact CB-CB 4.11Å; W590-A614 HydrophobicContact CD2-CB 4.49Å; W590-A614 HydrophobicContact CG-CB 3.91Å; T602-A614 WeakPolarHBondContact OG1-CA 3.31Å; T602-A614 WeakPolarHBondContact OG1-CB 3.28Å; T602-A614 PolarHBondContact OG1-N 2.98Å; T602-A614 PolarHBondContact OG1-O 3.34Å; A614-G616 WeakPolarHBondContact CB-O 3.5Å
615I94.5Very high92.6Very high35 Ų3548.1 Ų48.118%0.17925%0.246CC..SBendtrans-117.512.5167.560.6164.6000111.9F549 R551 G601 I663 T664 L667F549-I615 HydrophobicContact CB-CG1 4.06Å; F549-I615 HydrophobicContact CD1-CG1 4.09Å; F549-I615 HydrophobicContact CD2-CD1 3.78Å; F549-I615 HydrophobicContact CD2-CG1 3.37Å; F549-I615 HydrophobicContact CE1-CG1 4.41Å; F549-I615 HydrophobicContact CE2-CD1 4.24Å; F549-I615 HydrophobicContact CE2-CG1 3.75Å; F549-I615 HydrophobicContact CG-CD1 4.33Å; F549-I615 HydrophobicContact CG-CG1 3.57Å; F549-I615 HydrophobicContact CZ-CG1 4.25Å; R551-I615 VanDerWaalsContact CZ-O 3.24Å; R551-I615 PolarHBondContact NE-O 2.69Å; R551-I615 PolarHBondContact NH2-O 2.91Å; G601-I615 WeakPolarHBondContact CA-O 3.06Å; I615-I663 HydrophobicContact CD1-CB 4.47Å; I615-I663 HydrophobicContact CD1-CG2 4.03Å; I615-T664 VanDerWaalsContact CD1-O 3.26Å; I615-T664 WeakPolarHBondContact CD1-O 3.09Å; I615-L667 HydrophobicContact CD1-CD2 4.11Å
616G95.1Very high92.3Very high0 Ų047.7 Ų47.70%024%0.241CC..SBendtrans161.4-161-176.700000109.4Q606 A614 P618Q606-G616 PolarHBondContact NE2-O 2.97Å; A614-G616 WeakPolarHBondContact CB-O 3.5Å; G616-P618 VanDerWaalsContact O-CD 3.31Å; G616-P618 WeakPolarHBondContact O-CD 3.14Å
617S95.3Very high91.7Very high0 Ų051.8 Ų51.80%026%0.262CS..EExtended strand (participates in β ladder)trans-76.6115.6173.7-58.50000109.4F549 L550 D594F549-S617 CarbonylContact C-O 3.47Å; F549-S617 WeakPolarHBondContact CA-O 3.32Å; L550-S617 PolarHBondContact N-O 2.93Å; L550-S617 PolarHBondContact O-N 3.46Å; D594-S617 PolarHBondContact OD1-OG 3.36Å; D594-S617 VanDerWaalsContact OD2-CB 3.26Å; D594-S617 WeakPolarHBondContact OD2-CB 3.49Å; D594-S617 PolarHBondContact OD2-OG 3.06Å
618P95Very high91.4Very high3 Ų354 Ų542%0.01927%0.271CS..EExtended strand (participates in β ladder)trans-64.1142.6-178.627.3-38.6000111.8F549 R576 F587 W590 G616F549-P618 HydrophobicContact CD1-CB 4Å; F549-P618 HydrophobicContact CE1-CB 3.89Å; R576-P618 PolarHBondContact NH1-O 3.5Å; R576-P618 PolarHBondContact NH2-O 3.01Å; F587-P618 HydrophobicContact CD2-CB 4.1Å; F587-P618 HydrophobicContact CD2-CG 4.39Å; W590-P618 HydrophobicContact CB-CB 4.16Å; W590-P618 HydrophobicContact CB-CG 3.72Å; W590-P618 HydrophobicContact CE3-CB 4.39Å; G616-P618 VanDerWaalsContact O-CD 3.31Å; G616-P618 WeakPolarHBondContact O-CD 3.14Å
619M95.3Very high90.8Very high2 Ų255.8 Ų55.81%0.0128%0.277CS..PPolyproline II helixtrans-98.2149172.1-56.6-167.976.200110.6V536 I538 V548 L550 W642 M643 F644V536-M619 VanDerWaalsContact O-CE 3.3Å; V536-M619 WeakPolarHBondContact O-CE 3.23Å; I538-M619 HydrophobicContact CB-CE 4.24Å; I538-M619 HydrophobicContact CB-SD 4.21Å; I538-M619 HydrophobicContact CG1-CE 3.67Å; I538-M619 HydrophobicContact CG1-SD 3.7Å; V548-M619 HydrophobicContact CB-SD 4.43Å; V548-M619 HydrophobicContact CG1-CG 4.31Å; V548-M619 HydrophobicContact CG1-SD 3.65Å; V548-M619 WeakPolarHBondContact O-CB 3.46Å; V548-M619 PolarHBondContact O-N 3.09Å; L550-M619 HydrophobicContact CD1-CE 4.21Å; L550-M619 HydrophobicContact CD1-SD 4.32Å; L550-M619 HydrophobicContact CD2-CE 4.38Å; L550-M619 HydrophobicContact CD2-SD 3.69Å; L550-M619 HydrophobicContact CG-CE 4.23Å; L550-M619 HydrophobicContact CG-CG 3.94Å; L550-M619 HydrophobicContact CG-SD 3.69Å; M619-W642 HydrophobicContact CB-CB 3.83Å; M619-W642 HydrophobicContact CB-CE3 4.07Å; M619-W642 HydrophobicContact CE-CB 4.11Å; M619-W642 VanDerWaalsContact CE-O 3.24Å; M619-W642 WeakPolarHBondContact CE-O 3.36Å; M619-W642 VanDerWaalsContact O-CE3 3.27Å; M619-W642 WeakPolarHBondContact O-CZ3 3.27Å; M619-W642 HydrophobicContact SD-CB 4Å; M619-M643 CarbonylContact C-O 3.49Å; M619-M643 WeakPolarHBondContact CA-O 3.46Å; M619-F644 HydrophobicContact CE-CB 3.75Å; M619-F644 HydrophobicContact CG-CB 4.31Å
620L93.7Very high90.4Very high3 Ų353.8 Ų53.82%0.01627%0.271CS..EExtended strand (participates in β ladder)trans-86.8128.7176.6179.462.1000110.5T582 F587 T622 W642 M643T582-L620 HydrophobicContact CG2-CD1 3.92Å; F587-L620 HydrophobicContact CD1-CD1 4.08Å; F587-L620 HydrophobicContact CD2-CB 4.09Å; F587-L620 HydrophobicContact CD2-CD1 4.46Å; F587-L620 HydrophobicContact CE1-CD1 4.29Å; F587-L620 HydrophobicContact CE2-CB 3.75Å; F587-L620 HydrophobicContact CG-CD1 4.17Å; F587-L620 HydrophobicContact CZ-CB 3.99Å; L620-T622 HydrophobicContact CD2-CG2 4.45Å; L620-T622 HydrophobicContact CG-CG2 4.25Å; L620-W642 CarbonylContact O-C 3.47Å; L620-W642 WeakPolarHBondContact O-CA 3.48Å; L620-M643 HydrophobicContact CD2-CE 4.1Å; L620-M643 PolarHBondContact N-O 3.21Å; L620-M643 PolarHBondContact O-N 3Å
621W92.4Very high90.2Very high68 Ų6848.4 Ų48.426%0.25825%0.246SC..EExtended strand (participates in β ladder)trans-66.5131.5168.8179.2-97.7000110.6T542 H640 W642T542-W621 WeakPolarHBondContact OG1-CZ3 3.43Å; W621-H640 HydrophobicContact CH2-CB 4.13Å; W621-H640 AromaticContact CH2-ND1 3.51Å; W621-H640 HydrophobicContact CZ3-CB 4.48Å; W621-W642 HydrophobicContact CB-CE3 4.15Å; W621-W642 HydrophobicContact CB-CH2 4.13Å; W621-W642 HydrophobicContact CB-CZ3 3.9Å; W621-W642 HydrophobicContact CD2-CZ2 4.43Å; W621-W642 AromaticContact CE3-CD2 3.91Å; W621-W642 HydrophobicContact CE3-CD2 3.91Å; W621-W642 AromaticContact CE3-CE2 3.31Å; W621-W642 HydrophobicContact CE3-CG 4.37Å; W621-W642 HydrophobicContact CE3-CH2 4.12Å; W621-W642 AromaticContact CE3-CZ2 3.45Å; W621-W642 HydrophobicContact CE3-CZ2 3.45Å; W621-W642 VanDerWaalsContact CE3-CZ2 3.45Å; W621-W642 AromaticContact CE3-NE1 3.39Å; W621-W642 AromaticContact CZ3-CE2 3.74Å; W621-W642 AromaticContact CZ3-CZ2 3.94Å; W621-W642 HydrophobicContact CZ3-CZ2 3.94Å; W621-W642 AromaticContact CZ3-NE1 3.38Å
622T92.6Very high90.2Very high1 Ų141.4 Ų41.41%0.00621%0.209CC..EExtended strand (participates in β ladder)trans-131.9161.4-17972.20000114F537 L620 S630 N632 N635 F641 M643F537-T622 HydrophobicContact CE1-CG2 4.36Å; L620-T622 HydrophobicContact CD2-CG2 4.45Å; L620-T622 HydrophobicContact CG-CG2 4.25Å; T622-S630 CarbonylContact C-O 3.58Å; T622-S630 WeakPolarHBondContact CA-O 3.26Å; T622-N632 HydrophobicContact CG2-CB 3.81Å; T622-N635 PolarHBondContact OG1-ND2 3.43Å; T622-F641 PolarHBondContact N-O 2.93Å; T622-F641 PolarHBondContact OG1-O 3.31Å; T622-M643 HydrophobicContact CG2-CB 3.65Å; T622-M643 HydrophobicContact CG2-CE 4.45Å; T622-M643 HydrophobicContact CG2-SD 4.43Å
623S89.7Confident90Very high1 Ų135.6 Ų35.61%0.00719%0.185CC..BIsolated β-bridgetrans-133.3151.4174-179.70000110.2N625 D628 S630 F631 N632S623-N625 PolarHBondContact OG-N 2.89Å; S623-D628 VanDerWaalsContact CB-OD2 3.29Å; S623-D628 WeakPolarHBondContact CB-OD2 3.25Å; S623-D628 WeakPolarHBondContact OG-CB 3.24Å; S623-D628 PolarHBondContact OG-OD2 3.06Å; S623-D628 VanDerWaalsContact OG-OD2 3.13Å; S623-S630 WeakPolarHBondContact CB-OG 3.4Å; S623-S630 PolarHBondContact N-O 3.15Å; S623-F631 VanDerWaalsContact O-CA 3.3Å; S623-F631 WeakPolarHBondContact O-CA 3.46Å; S623-F631 WeakPolarHBondContact O-CD2 3.33Å; S623-N632 PolarHBondContact O-N 2.59Å
624D90.4Very high89.8Confident68 Ų6835.1 Ų35.136%0.36417%0.174SC..SBendtrans-93-6.1171.268-25.3000112.3N635 G638D624-N635 WeakPolarHBondContact CB-O 3.37Å; D624-G638 VanDerWaalsContact CG-CA 3.41Å; D624-G638 WeakPolarHBondContact OD1-CA 3.32Å; D624-G638 VanDerWaalsContact OD2-CA 3.26Å; D624-G638 WeakPolarHBondContact OD2-CA 3.45Å; D624-G638 PolarHBondContact OD2-N 3.18Å
625N87.3Confident89.7Confident74 Ų7434.9 Ų34.940%0.39617%0.172SC..  trans-81115.1173.3-179.92.4000110.5S623 L627 D628 F631S623-N625 PolarHBondContact OG-N 2.89Å; N625-L627 PolarHBondContact O-N 3.13Å; N625-L627 WeakPolarHBondContact OD1-CB 3.19Å; N625-L627 PolarHBondContact OD1-N 2.56Å; N625-D628 HydrophobicContact CB-CB 4.24Å; N625-D628 VanDerWaalsContact O-CB 3.25Å; N625-D628 WeakPolarHBondContact O-CB 3.31Å; N625-D628 PolarHBondContact O-N 2.72Å; N625-F631 WeakPolarHBondContact O-CB 3.37Å
626N81.1Confident89.6Confident84 Ų8439.7 Ų39.745%0.44919%0.191SC..THydrogen-bonded Turntrans-66.1-8.6-179.269.7-2.9000115.4F631N626-F631 HydrophobicContact CB-CD1 4.29Å; N626-F631 HydrophobicContact CB-CD2 4.17Å; N626-F631 HydrophobicContact CB-CE1 4.21Å; N626-F631 HydrophobicContact CB-CE2 4.07Å; N626-F631 HydrophobicContact CB-CG 4.28Å; N626-F631 HydrophobicContact CB-CZ 4.1Å
627L80.3Confident89.5Confident96 Ų9642.6 Ų42.650%0.50320%0.203SC..THydrogen-bonded Turntrans-87.4-14.4171.9-64.4172.9000113K465 Y466 N625K465-L627 HydrophobicContact CD-CD2 4.43Å; Y466-L627 HydrophobicContact CD1-CD2 4.17Å; Y466-L627 HydrophobicContact CE1-CD2 3.38Å; Y466-L627 HydrophobicContact CE1-CG 4.43Å; N625-L627 PolarHBondContact O-N 3.13Å; N625-L627 WeakPolarHBondContact OD1-CB 3.19Å; N625-L627 PolarHBondContact OD1-N 2.56Å
628D83.9Confident89.3Confident58 Ų5843.3 Ų43.331%0.3121%0.211SC..SBendtrans-80.1138.9-178.2-164.7-40.3000110.5S623 N625 S630 F631S623-D628 VanDerWaalsContact CB-OD2 3.29Å; S623-D628 WeakPolarHBondContact CB-OD2 3.25Å; S623-D628 WeakPolarHBondContact OG-CB 3.24Å; S623-D628 PolarHBondContact OG-OD2 3.06Å; S623-D628 VanDerWaalsContact OG-OD2 3.13Å; N625-D628 HydrophobicContact CB-CB 4.24Å; N625-D628 VanDerWaalsContact O-CB 3.25Å; N625-D628 WeakPolarHBondContact O-CB 3.31Å; N625-D628 PolarHBondContact O-N 2.72Å; D628-S630 PolarHBondContact O-N 3.04Å; D628-S630 WeakPolarHBondContact OD1-CB 3.4Å; D628-S630 PolarHBondContact OD1-N 2.77Å; D628-S630 PolarHBondContact OD1-OG 2.97Å; D628-S630 PolarHBondContact OD2-OG 2.93Å; D628-F631 VanDerWaalsContact O-CB 3.23Å; D628-F631 WeakPolarHBondContact O-CB 3.46Å; D628-F631 PolarHBondContact O-N 3.14Å
629K80.9Confident89Confident135 Ų13547.4 Ų47.459%0.58723%0.232SC*.THydrogen-bonded Turntrans-61.6-20.7172.2-66-169.4177.6-162.20112.6R512 E583R512-K629 PolarHBondContact NH1-O 3.21Å; E583-K629 IonicContact OE1-NZ 3.18Å; E583-K629 PolarHBondContact OE1-NZ 2.72Å; E583-K629 VanDerWaalsContact OE2-CD 3.25Å; E583-K629 WeakPolarHBondContact OE2-CD 3.49Å; E583-K629 IonicContact OE2-NZ 3.21Å; E583-K629 PolarHBondContact OE2-NZ 3.28Å
630S86.6Confident88.9Confident15 Ų1549.7 Ų49.711%0.10524%0.243CC..THydrogen-bonded Turntrans-93.77.4174.464.60000113.5T622 S623 D628 N632T622-S630 CarbonylContact C-O 3.58Å; T622-S630 WeakPolarHBondContact CA-O 3.26Å; S623-S630 WeakPolarHBondContact CB-OG 3.4Å; S623-S630 PolarHBondContact N-O 3.15Å; D628-S630 PolarHBondContact O-N 3.04Å; D628-S630 WeakPolarHBondContact OD1-CB 3.4Å; D628-S630 PolarHBondContact OD1-N 2.77Å; D628-S630 PolarHBondContact OD1-OG 2.97Å; D628-S630 PolarHBondContact OD2-OG 2.93Å; S630-N632 PolarHBondContact O-N 2.8Å
631F87.4Confident89Confident18 Ų1850.1 Ų50.18%0.07925%0.245CC..BIsolated β-bridgetrans-50.2133.8177.6177.9-118.7000111.8F510 S623 N625 N626 D628F510-F631 AromaticContact CE2-CD1 3.76Å; F510-F631 HydrophobicContact CE2-CD1 3.76Å; F510-F631 AromaticContact CE2-CE1 3.93Å; F510-F631 HydrophobicContact CE2-CE1 3.93Å; F510-F631 HydrophobicContact CZ-CD1 4.13Å; F510-F631 VanDerWaalsContact CZ-O 3.25Å; F510-F631 WeakPolarHBondContact CZ-O 3.42Å; S623-F631 VanDerWaalsContact O-CA 3.3Å; S623-F631 WeakPolarHBondContact O-CA 3.46Å; S623-F631 WeakPolarHBondContact O-CD2 3.33Å; N625-F631 WeakPolarHBondContact O-CB 3.37Å; N626-F631 HydrophobicContact CB-CD1 4.29Å; N626-F631 HydrophobicContact CB-CD2 4.17Å; N626-F631 HydrophobicContact CB-CE1 4.21Å; N626-F631 HydrophobicContact CB-CE2 4.07Å; N626-F631 HydrophobicContact CB-CG 4.28Å; N626-F631 HydrophobicContact CB-CZ 4.1Å; D628-F631 VanDerWaalsContact O-CB 3.23Å; D628-F631 WeakPolarHBondContact O-CB 3.46Å; D628-F631 PolarHBondContact O-N 3.14Å
632N90Very high89.2Confident7 Ų747.2 Ų47.24%0.03723%0.234CC..  trans-137.7131.7170.2-171.8-71.8000110.3T622 S623 S630 Y634 N635 M643T622-N632 HydrophobicContact CG2-CB 3.81Å; S623-N632 PolarHBondContact O-N 2.59Å; S630-N632 PolarHBondContact O-N 2.8Å; N632-Y634 PolarHBondContact O-N 2.95Å; N632-Y634 WeakPolarHBondContact OD1-CB 3.11Å; N632-Y634 PolarHBondContact OD1-N 3.36Å; N632-N635 PolarHBondContact O-N 3.14Å; N632-M643 WeakPolarHBondContact ND2-CE 3.37Å
633P89.5Confident89.3Confident13 Ų1347.1 Ų47.18%0.08423%0.233CC..THydrogen-bonded Turntrans-66.2-22.4-174.427.8-36.8000113.9D469 F510 K636D469-P633 HydrophobicContact CB-CB 4.25Å; D469-P633 VanDerWaalsContact CG-CB 3.42Å; D469-P633 WeakPolarHBondContact OD2-CB 3.16Å; F510-P633 HydrophobicContact CB-CG 4.1Å; F510-P633 HydrophobicContact CD1-CG 4.49Å; F510-P633 HydrophobicContact CD2-CG 3.8Å; F510-P633 HydrophobicContact CE2-CG 4.36Å; F510-P633 HydrophobicContact CG-CG 3.88Å; P633-K636 WeakPolarHBondContact O-CE 3.37Å; P633-K636 PolarHBondContact O-NZ 2.75Å
634Y91.4Very high89.6Confident51 Ų5147.1 Ų47.120%0.223%0.233CC..THydrogen-bonded Turntrans-78.1-21.2174.5-67.8-73.9000113.2N508 H533 I535 F537 N632 K636 L699N508-Y634 PolarHBondContact ND2-OH 2.9Å; H533-Y634 AromaticContact CE1-CZ 3.94Å; H533-Y634 PolarHBondContact CE1-OH 3.46Å; I535-Y634 HydrophobicContact CD1-CD1 3.63Å; I535-Y634 HydrophobicContact CD1-CD2 3.82Å; I535-Y634 HydrophobicContact CD1-CE1 3.78Å; I535-Y634 HydrophobicContact CD1-CE2 3.98Å; I535-Y634 HydrophobicContact CD1-CG 3.65Å; F537-Y634 WeakPolarHBondContact CE2-O 3.22Å; N632-Y634 PolarHBondContact O-N 2.95Å; N632-Y634 WeakPolarHBondContact OD1-CB 3.11Å; N632-Y634 PolarHBondContact OD1-N 3.36Å; Y634-K636 PolarHBondContact O-N 3.16Å; Y634-K636 VanDerWaalsContact O-N 3.16Å; Y634-L699 HydrophobicContact CD1-CD1 4.38Å
635N92.5Very high89.8Confident0 Ų044.2 Ų44.20%022%0.217CC..  trans-77.1104.7174.2-175.1-0.9000109.3F537 T622 D624 N632 Y637 G638F537-N635 HydrophobicContact CE1-CB 3.94Å; F537-N635 HydrophobicContact CZ-CB 3.84Å; T622-N635 PolarHBondContact OG1-ND2 3.43Å; D624-N635 WeakPolarHBondContact CB-O 3.37Å; N632-N635 PolarHBondContact O-N 3.14Å; N635-Y637 PolarHBondContact OD1-N 2.85Å; N635-G638 PolarHBondContact ND2-O 3.32Å; N635-G638 PolarHBondContact OD1-N 2.71Å; N635-G638 PolarHBondContact OD1-O 3.17Å
636K92.3Very high90.1Very high136 Ų13640.7 Ų40.759%0.59120%0.199SC*.  trans-114.918.4172.8-55.5-55.7-170.3-1520111.7P633 Y634P633-K636 WeakPolarHBondContact O-CE 3.37Å; P633-K636 PolarHBondContact O-NZ 2.75Å; Y634-K636 PolarHBondContact O-N 3.16Å; Y634-K636 VanDerWaalsContact O-N 3.16Å
637Y92Very high90.8Very high61 Ų6137.4 Ų37.424%0.23918%0.181CC..SBendtrans-115.4-8.6-165.4-51-72.5000113.6F537 N635 F641 L699 V701F537-Y637 HydrophobicContact CD2-CD2 4.2Å; F537-Y637 AromaticContact CD2-CE2 3.8Å; F537-Y637 HydrophobicContact CD2-CE2 3.8Å; F537-Y637 HydrophobicContact CE2-CE2 4.14Å; F537-Y637 HydrophobicContact CG-CD2 4.42Å; F537-Y637 HydrophobicContact CG-CE2 4.41Å; N635-Y637 PolarHBondContact OD1-N 2.85Å; Y637-F641 HydrophobicContact CG-CE1 4.29Å; Y637-F641 HydrophobicContact CG-CZ 4.19Å; Y637-F641 VanDerWaalsContact O-CE2 3.3Å; Y637-F641 WeakPolarHBondContact O-CE2 3.07Å; Y637-L699 HydrophobicContact CE2-CD2 4.11Å; Y637-L699 WeakPolarHBondContact OH-CD2 3.47Å; Y637-V701 HydrophobicContact CD1-CG1 4.24Å; Y637-V701 HydrophobicContact CD2-CG1 4.34Å; Y637-V701 HydrophobicContact CD2-CG2 4.45Å; Y637-V701 HydrophobicContact CE1-CG1 4.29Å; Y637-V701 HydrophobicContact CE1-CG2 3.81Å; Y637-V701 HydrophobicContact CE2-CG1 4.39Å; Y637-V701 HydrophobicContact CE2-CG2 3.71Å; Y637-V701 HydrophobicContact CG-CG1 4.28Å; Y637-V701 WeakPolarHBondContact OH-CG2 3.5Å
638G91.1Very high91.6Very high16 Ų1632.8 Ų32.817%0.16516%0.157CC..  trans108-163.8179.700000113.9D624 N635 F641D624-G638 VanDerWaalsContact CG-CA 3.41Å; D624-G638 WeakPolarHBondContact OD1-CA 3.32Å; D624-G638 VanDerWaalsContact OD2-CA 3.26Å; D624-G638 WeakPolarHBondContact OD2-CA 3.45Å; D624-G638 PolarHBondContact OD2-N 3.18Å; N635-G638 PolarHBondContact ND2-O 3.32Å; N635-G638 PolarHBondContact OD1-N 2.71Å; N635-G638 PolarHBondContact OD1-O 3.17Å; G638-F641 WeakPolarHBondContact O-CD2 3.44Å
639N89.6Confident92.2Very high89 Ų8930.8 Ų30.848%0.47615%0.146SC..SBendtrans-69.4161.6176.9-65.4-30.3000112.6F641N639-F641 VanDerWaalsContact C-N 3.32Å; N639-F641 WeakPolarHBondContact O-CD2 3.38Å; N639-F641 PolarHBondContact O-N 3.01Å
640H93Very high92.9Very high49 Ų4925.6 Ų25.623%0.22713%0.127CC..SBendtrans69.622.8172.9-42.3-72.9000115.2R539 K540 E541 W621R539-H640 CarbonylContact C-O 3.57Å; R539-H640 VanDerWaalsContact CA-O 3.29Å; R539-H640 WeakPolarHBondContact CA-O 3.38Å; K540-H640 PolarHBondContact N-O 2.89Å; E541-H640 HydrophobicContact CB-CB 4.43Å; W621-H640 HydrophobicContact CH2-CB 4.13Å; W621-H640 AromaticContact CH2-ND1 3.51Å; W621-H640 HydrophobicContact CZ3-CB 4.48Å
641F95.4Very high93.4Very high13 Ų1328.7 Ų28.76%0.05715%0.148CC..EExtended strand (participates in β ladder)trans-97.4119.4175-82.6-87.9000110.9F537 I538 R539 T622 Y637 G638 N639 V701F537-F641 HydrophobicContact CB-CD1 3.96Å; F537-F641 HydrophobicContact CD1-CB 3.91Å; F537-F641 HydrophobicContact CD1-CD1 4.28Å; F537-F641 HydrophobicContact CE1-CB 4.37Å; F537-F641 HydrophobicContact CG-CD1 4.41Å; I538-F641 WeakPolarHBondContact O-CA 3.28Å; R539-F641 HydrophobicContact CB-CD1 3.98Å; R539-F641 HydrophobicContact CB-CD2 4.4Å; R539-F641 HydrophobicContact CB-CE1 3.57Å; R539-F641 HydrophobicContact CB-CE2 3.99Å; R539-F641 HydrophobicContact CB-CG 4.41Å; R539-F641 HydrophobicContact CB-CZ 3.58Å; R539-F641 HydrophobicContact CG-CD2 4.25Å; R539-F641 HydrophobicContact CG-CE1 4.32Å; R539-F641 HydrophobicContact CG-CE2 3.82Å; R539-F641 HydrophobicContact CG-CZ 3.89Å; T622-F641 PolarHBondContact N-O 2.93Å; T622-F641 PolarHBondContact OG1-O 3.31Å; Y637-F641 HydrophobicContact CG-CE1 4.29Å; Y637-F641 HydrophobicContact CG-CZ 4.19Å; Y637-F641 VanDerWaalsContact O-CE2 3.3Å; Y637-F641 WeakPolarHBondContact O-CE2 3.07Å; G638-F641 WeakPolarHBondContact O-CD2 3.44Å; N639-F641 VanDerWaalsContact C-N 3.32Å; N639-F641 WeakPolarHBondContact O-CD2 3.38Å; N639-F641 PolarHBondContact O-N 3.01Å; F641-V701 HydrophobicContact CE1-CG1 3.7Å; F641-V701 HydrophobicContact CZ-CG1 4.43Å
642W95.7Very high93.7Very high6 Ų633.4 Ų33.42%0.02317%0.169CC..EExtended strand (participates in β ladder)trans-90.2138.5170.6-67.284.6000109.8F537 I538 K540 T542 Q546 V548 M619 L620 W621F537-W642 CarbonylContact C-O 3.45Å; F537-W642 VanDerWaalsContact CA-O 3.25Å; F537-W642 WeakPolarHBondContact CA-O 3.43Å; I538-W642 PolarHBondContact N-O 3.14Å; I538-W642 PolarHBondContact O-N 2.88Å; K540-W642 PolarHBondContact O-NE1 2.92Å; T542-W642 HydrophobicContact CG2-CZ2 3.67Å; T542-W642 WeakPolarHBondContact OG1-CZ2 3.44Å; Q546-W642 WeakPolarHBondContact O-CH2 3.34Å; Q546-W642 WeakPolarHBondContact O-CZ2 3.43Å; V548-W642 HydrophobicContact CB-CB 4.28Å; V548-W642 HydrophobicContact CB-CD2 3.68Å; V548-W642 HydrophobicContact CB-CE3 4.11Å; V548-W642 HydrophobicContact CB-CG 3.77Å; V548-W642 HydrophobicContact CG1-CG 4.42Å; V548-W642 HydrophobicContact CG2-CD2 3.7Å; V548-W642 VanDerWaalsContact CG2-CE2 3.43Å; V548-W642 HydrophobicContact CG2-CE3 4.49Å; V548-W642 HydrophobicContact CG2-CG 3.77Å; V548-W642 HydrophobicContact CG2-CZ2 4.06Å; M619-W642 HydrophobicContact CB-CB 3.83Å; M619-W642 HydrophobicContact CB-CE3 4.07Å; M619-W642 HydrophobicContact CE-CB 4.11Å; M619-W642 VanDerWaalsContact CE-O 3.24Å; M619-W642 WeakPolarHBondContact CE-O 3.36Å; M619-W642 VanDerWaalsContact O-CE3 3.27Å; M619-W642 WeakPolarHBondContact O-CZ3 3.27Å; M619-W642 HydrophobicContact SD-CB 4Å; L620-W642 CarbonylContact O-C 3.47Å; L620-W642 WeakPolarHBondContact O-CA 3.48Å; W621-W642 HydrophobicContact CB-CE3 4.15Å; W621-W642 HydrophobicContact CB-CH2 4.13Å; W621-W642 HydrophobicContact CB-CZ3 3.9Å; W621-W642 HydrophobicContact CD2-CZ2 4.43Å; W621-W642 AromaticContact CE3-CD2 3.91Å; W621-W642 HydrophobicContact CE3-CD2 3.91Å; W621-W642 AromaticContact CE3-CE2 3.31Å; W621-W642 HydrophobicContact CE3-CG 4.37Å; W621-W642 HydrophobicContact CE3-CH2 4.12Å; W621-W642 AromaticContact CE3-CZ2 3.45Å; W621-W642 HydrophobicContact CE3-CZ2 3.45Å; W621-W642 VanDerWaalsContact CE3-CZ2 3.45Å; W621-W642 AromaticContact CE3-NE1 3.39Å; W621-W642 AromaticContact CZ3-CE2 3.74Å; W621-W642 AromaticContact CZ3-CZ2 3.94Å; W621-W642 HydrophobicContact CZ3-CZ2 3.94Å; W621-W642 AromaticContact CZ3-NE1 3.38Å
643M95.7Very high94Very high0 Ų033.9 Ų33.90%017%0.171CC..EExtended strand (participates in β ladder)trans-118.1135.1-174.2-166.2-17967.900111.7I535 V536 F537 D578 M619 L620 T622 N632 D645I535-M643 HydrophobicContact CG2-CG 3.87Å; I535-M643 HydrophobicContact CG2-SD 4.27Å; V536-M643 CarbonylContact O-C 3.6Å; V536-M643 WeakPolarHBondContact O-CA 3.35Å; F537-M643 HydrophobicContact CD1-CB 3.94Å; F537-M643 HydrophobicContact CD1-CG 4.12Å; F537-M643 HydrophobicContact CE1-CB 3.52Å; F537-M643 HydrophobicContact CE1-CG 3.6Å; F537-M643 HydrophobicContact CE1-SD 3.97Å; F537-M643 HydrophobicContact CE2-CG 4.27Å; F537-M643 HydrophobicContact CE2-SD 4.29Å; F537-M643 HydrophobicContact CZ-CB 4.11Å; F537-M643 HydrophobicContact CZ-CG 3.67Å; F537-M643 HydrophobicContact CZ-SD 3.56Å; F537-M643 VanDerWaalsContact CZ-SD 3.56Å; D578-M643 HydrophobicContact CB-CE 4.31Å; M619-M643 CarbonylContact C-O 3.49Å; M619-M643 WeakPolarHBondContact CA-O 3.46Å; L620-M643 HydrophobicContact CD2-CE 4.1Å; L620-M643 PolarHBondContact N-O 3.21Å; L620-M643 PolarHBondContact O-N 3Å; T622-M643 HydrophobicContact CG2-CB 3.65Å; T622-M643 HydrophobicContact CG2-CE 4.45Å; T622-M643 HydrophobicContact CG2-SD 4.43Å; N632-M643 WeakPolarHBondContact ND2-CE 3.37Å; M643-D645 HydrophobicContact CE-CB 3.76Å; M643-D645 HydrophobicContact CG-CB 4.34Å; M643-D645 HydrophobicContact SD-CB 4.25Å
644F95.8Very high94.2Very high0 Ų034.2 Ų34.20%018%0.176CC..EExtended strand (participates in β ladder)trans-119.1112.7166.5172.7-104.4000107.4I535 V536 L550 I574 M619 V646 M648I535-F644 CarbonylContact C-O 3.49Å; I535-F644 VanDerWaalsContact CA-O 3.31Å; I535-F644 WeakPolarHBondContact CA-O 3.49Å; V536-F644 HydrophobicContact CB-CB 4.24Å; V536-F644 HydrophobicContact CB-CD1 4.4Å; V536-F644 HydrophobicContact CG2-CD1 4.25Å; V536-F644 PolarHBondContact N-O 3.4Å; V536-F644 PolarHBondContact O-N 2.62Å; L550-F644 HydrophobicContact CD1-CB 3.58Å; L550-F644 HydrophobicContact CD1-CD1 3.66Å; L550-F644 HydrophobicContact CD1-CD2 4.26Å; L550-F644 HydrophobicContact CD1-CE1 4.35Å; L550-F644 HydrophobicContact CD1-CG 3.59Å; L550-F644 HydrophobicContact CG-CB 4.44Å; I574-F644 HydrophobicContact CD1-CE2 3.91Å; I574-F644 HydrophobicContact CD1-CZ 3.69Å; I574-F644 HydrophobicContact CG2-CZ 4.26Å; M619-F644 HydrophobicContact CE-CB 3.75Å; M619-F644 HydrophobicContact CG-CB 4.31Å; F644-V646 HydrophobicContact CD1-CG1 4.25Å; F644-V646 HydrophobicContact CD1-CG2 4.16Å; F644-V646 HydrophobicContact CD2-CG1 4.1Å; F644-V646 HydrophobicContact CE1-CB 4.29Å; F644-V646 HydrophobicContact CE1-CG1 3.77Å; F644-V646 HydrophobicContact CE1-CG2 3.46Å; F644-V646 VanDerWaalsContact CE1-CG2 3.46Å; F644-V646 HydrophobicContact CE2-CG1 3.57Å; F644-V646 HydrophobicContact CG-CG1 4.42Å; F644-V646 HydrophobicContact CZ-CB 4.26Å; F644-V646 HydrophobicContact CZ-CG1 3.41Å; F644-V646 VanDerWaalsContact CZ-CG1 3.41Å; F644-V646 HydrophobicContact CZ-CG2 3.82Å; F644-M648 HydrophobicContact CE1-CE 4.28Å
645D94.4Very high94.2Very high7 Ų735.5 Ų35.54%0.03720%0.204CC..EExtended strand (participates in β ladder)trans-123.1108.9-171.2-177.44.7000110.7H533 I535 V577 D578 M643H533-D645 IonicContact CD2-OD1 3.53Å; H533-D645 PolarHBondContact CD2-OD1 2.04Å; H533-D645 IonicContact CE1-OD1 2.68Å; H533-D645 IonicContact NE2-OD1 2.65Å; H533-D645 PolarHBondContact NE2-OD1 3Å; H533-D645 IonicContact NE2-OD2 3.43Å; I535-D645 HydrophobicContact CG1-CB 4.36Å; V577-D645 PolarHBondContact N-O 3.47Å; D578-D645 HydrophobicContact CB-CB 3.91Å; D578-D645 PolarHBondContact N-O 3.26Å; M643-D645 HydrophobicContact CE-CB 3.76Å; M643-D645 HydrophobicContact CG-CB 4.34Å; M643-D645 HydrophobicContact SD-CB 4.25Å
646V94.9Very high94.3Very high0 Ų036.6 Ų36.60%022%0.215CC..EExtended strand (participates in β ladder)trans-143.1158.3-171.1-57.10000113.4H533 T534 I574 V575 F644 M648H533-V646 CarbonylContact C-O 3.57Å; H533-V646 WeakPolarHBondContact CA-O 3.39Å; T534-V646 PolarHBondContact N-O 3.1Å; T534-V646 PolarHBondContact O-N 2.94Å; T534-V646 VanDerWaalsContact O-N 3.08Å; I574-V646 HydrophobicContact CB-CB 4.09Å; I574-V646 HydrophobicContact CB-CG1 4.24Å; I574-V646 HydrophobicContact CB-CG2 4.23Å; I574-V646 HydrophobicContact CD1-CG1 4.24Å; I574-V646 HydrophobicContact CG2-CB 4.39Å; I574-V646 HydrophobicContact CG2-CG2 3.96Å; V575-V646 CarbonylContact O-C 3.55Å; V575-V646 VanDerWaalsContact O-CA 3.23Å; V575-V646 WeakPolarHBondContact O-CA 3.35Å; V575-V646 WeakPolarHBondContact O-CB 3.45Å; F644-V646 HydrophobicContact CD1-CG1 4.25Å; F644-V646 HydrophobicContact CD1-CG2 4.16Å; F644-V646 HydrophobicContact CD2-CG1 4.1Å; F644-V646 HydrophobicContact CE1-CB 4.29Å; F644-V646 HydrophobicContact CE1-CG1 3.77Å; F644-V646 HydrophobicContact CE1-CG2 3.46Å; F644-V646 VanDerWaalsContact CE1-CG2 3.46Å; F644-V646 HydrophobicContact CE2-CG1 3.57Å; F644-V646 HydrophobicContact CG-CG1 4.42Å; F644-V646 HydrophobicContact CZ-CB 4.26Å; F644-V646 HydrophobicContact CZ-CG1 3.41Å; F644-V646 VanDerWaalsContact CZ-CG1 3.41Å; F644-V646 HydrophobicContact CZ-CG2 3.82Å; V646-M648 HydrophobicContact CG2-CB 4.19Å; V646-M648 HydrophobicContact CG2-CE 4.29Å
647M94.9Very high94.4Very high15 Ų1531.2 Ų31.27%0.07419%0.191CC..EExtended strand (participates in β ladder)trans-83.2118.8153.6-60-63.6-65.300108.4V480 V500 L527 F531 H533 I574 V575 V577V480-M647 HydrophobicContact CG2-CE 3.91Å; V480-M647 HydrophobicContact CG2-CG 3.92Å; V480-M647 HydrophobicContact CG2-SD 4.11Å; V500-M647 HydrophobicContact CG2-SD 3.94Å; L527-M647 HydrophobicContact CD1-CB 3.96Å; L527-M647 HydrophobicContact CD1-CG 4.13Å; F531-M647 HydrophobicContact CB-CB 4.49Å; F531-M647 HydrophobicContact CB-CE 4.26Å; F531-M647 HydrophobicContact CD1-CB 3.97Å; H533-M647 HydrophobicContact CB-SD 3.82Å; I574-M647 CarbonylContact C-O 3.44Å; I574-M647 VanDerWaalsContact CA-O 3.23Å; I574-M647 WeakPolarHBondContact CA-O 3.44Å; V575-M647 HydrophobicContact CB-CB 4.22Å; V575-M647 PolarHBondContact N-O 2.84Å; V575-M647 PolarHBondContact O-N 3.16Å; V577-M647 HydrophobicContact CG2-CG 3.62Å; V577-M647 HydrophobicContact CG2-SD 4.25Å
648M96.6Very high94.6Very high0 Ų028.3 Ų28.30%018%0.18CC..EExtended strand (participates in β ladder)trans-110.5132.6-176.8-176.8178.3-71.100111.3F531 K532 T534 I572 I574 L597 F644 V646 C650 T653 F658 C696F531-M648 CarbonylContact C-O 3.6Å; F531-M648 VanDerWaalsContact CA-O 3.23Å; F531-M648 WeakPolarHBondContact CA-O 3.4Å; K532-M648 PolarHBondContact N-O 2.91Å; K532-M648 PolarHBondContact O-N 2.91Å; T534-M648 HydrophobicContact CG2-CE 4.09Å; T534-M648 HydrophobicContact CG2-SD 4.28Å; I572-M648 HydrophobicContact CG2-CG 3.47Å; I572-M648 VanDerWaalsContact CG2-CG 3.47Å; I572-M648 HydrophobicContact CG2-SD 4.15Å; I574-M648 HydrophobicContact CG2-CE 4.49Å; I574-M648 HydrophobicContact CG2-CG 4.47Å; L597-M648 HydrophobicContact CD2-CE 4.03Å; F644-M648 HydrophobicContact CE1-CE 4.28Å; V646-M648 HydrophobicContact CG2-CB 4.19Å; V646-M648 HydrophobicContact CG2-CE 4.29Å; M648-C650 PolarHBondContact O-N 3.21Å; M648-T653 HydrophobicContact SD-CG2 4.34Å; M648-F658 HydrophobicContact CE-CD1 4.09Å; M648-F658 HydrophobicContact CE-CD2 4.22Å; M648-F658 HydrophobicContact CE-CE1 3.88Å; M648-F658 HydrophobicContact CE-CE2 4.02Å; M648-F658 HydrophobicContact CE-CG 4.25Å; M648-F658 HydrophobicContact CE-CZ 3.84Å; M648-F658 HydrophobicContact SD-CD1 3.5Å; M648-F658 WeakPolarHBondContact SD-CD1 3.01Å; M648-F658 HydrophobicContact SD-CE1 3.69Å; M648-F658 HydrophobicContact SD-CG 3.94Å; M648-F658 HydrophobicContact SD-CZ 4.28Å; M648-C696 HydrophobicContact SD-CB 4.25Å
649D96.4Very high94.8Very high15 Ų1527.5 Ų27.58%0.0817%0.172CC..EExtended strand (participates in β ladder)trans-70.593.1175-172.1-1.1000111.6S530 F531 R573 S651 K652S530-D649 WeakPolarHBondContact CB-OD1 3.46Å; S530-D649 PolarHBondContact OG-OD1 3.17Å; F531-D649 HydrophobicContact CD1-CB 4.41Å; F531-D649 HydrophobicContact CD2-CB 4.04Å; F531-D649 HydrophobicContact CE1-CB 4.02Å; F531-D649 HydrophobicContact CE2-CB 3.6Å; F531-D649 HydrophobicContact CG-CB 4.44Å; F531-D649 HydrophobicContact CZ-CB 3.61Å; R573-D649 HydrophobicContact CB-CB 4.3Å; R573-D649 PolarHBondContact O-N 3.18Å; D649-S651 VanDerWaalsContact CG-OG 3.23Å; D649-S651 PolarHBondContact O-N 3.1Å; D649-S651 VanDerWaalsContact OD1-CB 3.32Å; D649-S651 WeakPolarHBondContact OD1-CB 3.4Å; D649-S651 PolarHBondContact OD1-N 3.18Å; D649-S651 PolarHBondContact OD1-OG 3.02Å; D649-S651 PolarHBondContact OD2-OG 3Å; D649-K652 HydrophobicContact CB-CG 4.25Å; D649-K652 PolarHBondContact O-N 3.46Å; D649-K652 WeakPolarHBondContact OD2-CG 3.42Å
650C97Very high95.2Very high27 Ų2723.3 Ų23.318%0.18215%0.149CC..G310 helixtrans-65-13.6-179.4-51.80000113.2S530 K532 M648 K652 T653 C696S530-C650 VanDerWaalsContact O-CB 3.27Å; S530-C650 WeakPolarHBondContact O-CB 3.48Å; S530-C650 PolarHBondContact O-N 2.95Å; S530-C650 PolarHBondContact O-SG 2.97Å; S530-C650 VanDerWaalsContact O-SG 3.37Å; K532-C650 VanDerWaalsContact CB-SG 3.55Å; K532-C650 WeakPolarHBondContact CG-SG 3.36Å; M648-C650 PolarHBondContact O-N 3.21Å; C650-K652 PolarHBondContact O-N 3.45Å; C650-T653 WeakPolarHBondContact O-CB 3Å; C650-T653 PolarHBondContact O-N 2.89Å; C650-T653 PolarHBondContact O-OG1 3.15Å; C650-C696 WeakPolarHBondContact CA-SG 3.46Å; C650-C696 HydrophobicContact CB-CB 3.85Å; C650-C696 WeakPolarHBondContact CB-SG 3.43Å; C650-C696 WeakPolarHBondContact SG-CB 3.49Å; C650-C696 CovalentContact SG-SG 2.03Å; C650-C696 PolarHBondContact SG-SG 2.74Å
651S95.6Very high95.3Very high79 Ų7923.4 Ų23.455%0.55215%0.149SC*.G310 helixtrans-70-18.9174.576.10000112.9D649D649-S651 VanDerWaalsContact CG-OG 3.23Å; D649-S651 PolarHBondContact O-N 3.1Å; D649-S651 VanDerWaalsContact OD1-CB 3.32Å; D649-S651 WeakPolarHBondContact OD1-CB 3.4Å; D649-S651 PolarHBondContact OD1-N 3.18Å; D649-S651 PolarHBondContact OD1-OG 3.02Å; D649-S651 PolarHBondContact OD2-OG 3Å
652K94.7Very high95.3Very high118 Ų11822.8 Ų22.851%0.51315%0.146SC..G310 helixtrans-91.80.2175-58.2-61-178.6178.50113V554 I572 D649 C650V554-K652 WeakPolarHBondContact CG1-O 3.21Å; I572-K652 HydrophobicContact CB-CB 4.41Å; I572-K652 HydrophobicContact CG1-CB 4.07Å; I572-K652 HydrophobicContact CG2-CB 4.24Å; D649-K652 HydrophobicContact CB-CG 4.25Å; D649-K652 PolarHBondContact O-N 3.46Å; D649-K652 WeakPolarHBondContact OD2-CG 3.42Å; C650-K652 PolarHBondContact O-N 3.45Å
653T95.4Very high95.4Very high16 Ų1622.7 Ų22.710%0.09815%0.146CC..SBendtrans-93.1158.6178.970.80000111.2I572 M648 C650 G655 G656 W657 F658 C696I572-T653 HydrophobicContact CD1-CG2 4.01Å; M648-T653 HydrophobicContact SD-CG2 4.34Å; C650-T653 WeakPolarHBondContact O-CB 3Å; C650-T653 PolarHBondContact O-N 2.89Å; C650-T653 PolarHBondContact O-OG1 3.15Å; T653-G655 PolarHBondContact O-N 3.33Å; T653-G656 WeakPolarHBondContact OG1-CA 3.36Å; T653-G656 PolarHBondContact OG1-N 2.99Å; T653-G656 VanDerWaalsContact OG1-N 3.16Å; T653-W657 VanDerWaalsContact CB-O 3.31Å; T653-W657 WeakPolarHBondContact CB-O 3.34Å; T653-F658 HydrophobicContact CG2-CB 4.33Å; T653-C696 HydrophobicContact CG2-CB 3.96Å
654A93.2Very high95.4Very high21 Ų2122.7 Ų22.717%0.17415%0.146CC..BIsolated β-bridgetrans-85.491.3177.100000110.6T558 G656 W657 Y687T558-A654 HydrophobicContact CG2-CB 3.9Å; A654-G656 PolarHBondContact O-N 2.84Å; A654-W657 PolarHBondContact N-O 3.13Å; A654-W657 WeakPolarHBondContact O-CB 3.41Å; A654-W657 PolarHBondContact O-N 2.89Å; A654-W657 VanDerWaalsContact O-N 3.08Å; A654-Y687 HydrophobicContact CB-CE1 4.04Å
655G91.7Very high95.1Very high78 Ų7825.6 Ų25.680%0.80416%0.162SC*.THydrogen-bonded Turntrans62.731.2-178.800000113.6T653T653-G655 PolarHBondContact O-N 3.33Å
656G94.4Very high95Very high22 Ų2229.1 Ų29.123%0.22718%0.181CC..THydrogen-bonded Turntrans92.7-0.6-175.100000114.6T653 A654 C696T653-G656 WeakPolarHBondContact OG1-CA 3.36Å; T653-G656 PolarHBondContact OG1-N 2.99Å; T653-G656 VanDerWaalsContact OG1-N 3.16Å; A654-G656 PolarHBondContact O-N 2.84Å; G656-C696 WeakPolarHBondContact O-CB 3Å; G656-C696 PolarHBondContact O-N 3.13Å
657W95.5Very high94.8Very high23 Ų2334.7 Ų34.79%0.08721%0.21CC..EExtended strand (participates in β ladder)trans-110139.8-177.1-62.389.5000112.5T653 A654 V683 L685 P686 Y687 L693 G694 R695 Y711T653-W657 VanDerWaalsContact CB-O 3.31Å; T653-W657 WeakPolarHBondContact CB-O 3.34Å; A654-W657 PolarHBondContact N-O 3.13Å; A654-W657 WeakPolarHBondContact O-CB 3.41Å; A654-W657 PolarHBondContact O-N 2.89Å; A654-W657 VanDerWaalsContact O-N 3.08Å; W657-V683 HydrophobicContact CH2-CG1 3.95Å; W657-V683 HydrophobicContact CZ2-CG1 4.24Å; W657-L685 HydrophobicContact CZ3-CD2 4.48Å; W657-P686 HydrophobicContact CB-CG 4.2Å; W657-P686 HydrophobicContact CD2-CG 3.81Å; W657-P686 HydrophobicContact CG-CB 4.49Å; W657-P686 HydrophobicContact CG-CG 3.62Å; W657-Y687 HydrophobicContact CB-CE1 4.28Å; W657-L693 HydrophobicContact CE3-CB 4.12Å; W657-L693 HydrophobicContact CZ3-CB 4.37Å; W657-G694 WeakPolarHBondContact CA-O 3.26Å; W657-R695 HydrophobicContact CD2-CG 4.45Å; W657-R695 HydrophobicContact CE3-CB 4.15Å; W657-R695 HydrophobicContact CE3-CG 4.5Å; W657-R695 HydrophobicContact CH2-CB 4.35Å; W657-R695 HydrophobicContact CH2-CG 4.45Å; W657-R695 HydrophobicContact CZ2-CG 4.4Å; W657-R695 HydrophobicContact CZ3-CB 4.02Å; W657-R695 HydrophobicContact CZ3-CG 4.48Å; W657-Y711 HydrophobicContact CH2-CD2 4.29Å; W657-Y711 AromaticContact CH2-CE2 3.7Å; W657-Y711 HydrophobicContact CH2-CE2 3.7Å; W657-Y711 AromaticContact CH2-CZ 3.96Å; W657-Y711 HydrophobicContact CZ3-CE1 4.12Å; W657-Y711 AromaticContact CZ3-CE2 3.79Å; W657-Y711 HydrophobicContact CZ3-CE2 3.79Å; W657-Y711 AromaticContact CZ3-CZ 3.52Å; W657-Y711 WeakPolarHBondContact CZ3-OH 3.47Å
658F96.5Very high94.7Very high0 Ų038 Ų380%023%0.225CC..EExtended strand (participates in β ladder)trans-126.1156.717364.8-85.7000109.8T534 V536 I572 L597 M648 T653 F660 L693 G694T534-F658 HydrophobicContact CG2-CE1 3.82Å; T534-F658 HydrophobicContact CG2-CZ 4.04Å; V536-F658 HydrophobicContact CG2-CE2 4.21Å; V536-F658 HydrophobicContact CG2-CZ 3.82Å; I572-F658 HydrophobicContact CD1-CB 3.41Å; I572-F658 VanDerWaalsContact CD1-CB 3.41Å; I572-F658 HydrophobicContact CD1-CG 4.4Å; L597-F658 HydrophobicContact CD2-CD2 3.7Å; L597-F658 HydrophobicContact CD2-CE2 4.05Å; M648-F658 HydrophobicContact CE-CD1 4.09Å; M648-F658 HydrophobicContact CE-CD2 4.22Å; M648-F658 HydrophobicContact CE-CE1 3.88Å; M648-F658 HydrophobicContact CE-CE2 4.02Å; M648-F658 HydrophobicContact CE-CG 4.25Å; M648-F658 HydrophobicContact CE-CZ 3.84Å; M648-F658 HydrophobicContact SD-CD1 3.5Å; M648-F658 WeakPolarHBondContact SD-CD1 3.01Å; M648-F658 HydrophobicContact SD-CE1 3.69Å; M648-F658 HydrophobicContact SD-CG 3.94Å; M648-F658 HydrophobicContact SD-CZ 4.28Å; T653-F658 HydrophobicContact CG2-CB 4.33Å; F658-F660 AromaticContact CD2-CD1 3.97Å; F658-F660 HydrophobicContact CD2-CD1 3.97Å; F658-F660 AromaticContact CE2-CD1 3.57Å; F658-F660 HydrophobicContact CE2-CD1 3.57Å; F658-F660 HydrophobicContact CE2-CE1 4.14Å; F658-F660 HydrophobicContact CE2-CG 4.39Å; F658-L693 CarbonylContact O-C 3.58Å; F658-L693 WeakPolarHBondContact O-CA 3.39Å; F658-G694 VanDerWaalsContact CD1-O 3.3Å; F658-G694 WeakPolarHBondContact CD1-O 3.28Å; F658-G694 PolarHBondContact N-O 3.38Å; F658-G694 PolarHBondContact O-N 3.4Å
659E95.6Very high94.6Very high0 Ų042.8 Ų42.80%025%0.247CC..EExtended strand (participates in β ladder)trans-108.9146.8178.6-72.3174.8-116.700110.2G552 G553 M555 H557 W599 Y687 T689 N691 N692 L693G552-E659 CarbonylContact C-O 3.52Å; G552-E659 WeakPolarHBondContact CA-O 3.44Å; G553-E659 PolarHBondContact N-O 3.06Å; G553-E659 PolarHBondContact O-N 3.46Å; M555-E659 WeakPolarHBondContact CB-OE1 3.48Å; M555-E659 VanDerWaalsContact CG-OE2 3.23Å; M555-E659 WeakPolarHBondContact CG-OE2 3.46Å; H557-E659 IonicContact CE1-OE1 3.77Å; H557-E659 PolarHBondContact CE1-OE1 2.98Å; H557-E659 IonicContact CE1-OE2 3.94Å; H557-E659 IonicContact NE2-OE1 2.77Å; H557-E659 PolarHBondContact NE2-OE1 3.33Å; W599-E659 HydrophobicContact CH2-CB 4.12Å; W599-E659 HydrophobicContact CZ2-CB 3.61Å; E659-Y687 HydrophobicContact CG-CE2 4.22Å; E659-Y687 WeakPolarHBondContact OE1-CE2 3.37Å; E659-T689 HydrophobicContact CG-CG2 4.23Å; E659-T689 WeakPolarHBondContact OE2-CB 3.34Å; E659-T689 PolarHBondContact OE2-OG1 3.27Å; E659-N691 HydrophobicContact CB-CB 4.07Å; E659-N691 HydrophobicContact CG-CB 4.44Å; E659-N691 PolarHBondContact OE2-ND2 3.16Å; E659-N692 CarbonylContact C-O 3.59Å; E659-N692 VanDerWaalsContact CA-O 3.29Å; E659-N692 WeakPolarHBondContact CA-O 3.24Å; E659-L693 HydrophobicContact CG-CD2 3.55Å
660F96.1Very high94.4Very high0 Ų042.7 Ų42.70%025%0.248CC..EExtended strand (participates in β ladder)trans-156.4164.4175.570.7-88.4000112.7V536 I538 L550 R551 F658 N692 Y702V536-F660 HydrophobicContact CG1-CE1 4.45Å; V536-F660 HydrophobicContact CG1-CE2 4.21Å; V536-F660 HydrophobicContact CG1-CZ 3.94Å; I538-F660 HydrophobicContact CD1-CE2 3.8Å; I538-F660 HydrophobicContact CD1-CZ 4.23Å; L550-F660 HydrophobicContact CD2-CD2 3.69Å; L550-F660 HydrophobicContact CD2-CE2 4.08Å; R551-F660 CarbonylContact O-C 3.56Å; R551-F660 WeakPolarHBondContact O-CA 3.24Å; R551-F660 VanDerWaalsContact O-CB 3.28Å; R551-F660 WeakPolarHBondContact O-CB 3.38Å; F658-F660 AromaticContact CD2-CD1 3.97Å; F658-F660 HydrophobicContact CD2-CD1 3.97Å; F658-F660 AromaticContact CE2-CD1 3.57Å; F658-F660 HydrophobicContact CE2-CD1 3.57Å; F658-F660 HydrophobicContact CE2-CE1 4.14Å; F658-F660 HydrophobicContact CE2-CG 4.39Å; F660-N692 HydrophobicContact CD1-CB 4.26Å; F660-N692 HydrophobicContact CD2-CB 4.2Å; F660-N692 HydrophobicContact CE1-CB 3.83Å; F660-N692 HydrophobicContact CE2-CB 3.75Å; F660-N692 HydrophobicContact CG-CB 4.43Å; F660-N692 HydrophobicContact CZ-CB 3.55Å; F660-N692 PolarHBondContact N-O 3.06Å; F660-N692 WeakPolarHBondContact O-CB 3.3Å; F660-N692 PolarHBondContact O-N 2.61Å; F660-Y702 HydrophobicContact CE1-CE1 4.24Å; F660-Y702 AromaticContact CE1-CE2 3.86Å; F660-Y702 HydrophobicContact CE1-CE2 3.86Å; F660-Y702 AromaticContact CE1-CZ 3.69Å; F660-Y702 HydrophobicContact CZ-CD1 4.11Å; F660-Y702 AromaticContact CZ-CD2 3.72Å; F660-Y702 HydrophobicContact CZ-CD2 3.72Å; F660-Y702 AromaticContact CZ-CE1 3.85Å; F660-Y702 HydrophobicContact CZ-CE1 3.85Å; F660-Y702 AromaticContact CZ-CE2 3.41Å; F660-Y702 HydrophobicContact CZ-CE2 3.41Å; F660-Y702 VanDerWaalsContact CZ-CE2 3.41Å; F660-Y702 HydrophobicContact CZ-CG 4.08Å; F660-Y702 AromaticContact CZ-CZ 3.51Å
661K95.6Very high94Very high51 Ų5144.7 Ų44.722%0.22226%0.259CS..EExtended strand (participates in β ladder)trans-123.9140.2163-71.1-172.9175.7-173.20109.1R551 W599 I663 E669 N691R551-K661 PolarHBondContact N-O 3.09Å; R551-K661 PolarHBondContact O-N 3.4Å; W599-K661 HydrophobicContact CZ3-CB 4.49Å; W599-K661 HydrophobicContact CZ3-CG 4.23Å; K661-I663 HydrophobicContact CB-CG1 4.22Å; K661-E669 WeakPolarHBondContact CD-OE2 3.4Å; K661-E669 IonicContact NZ-OE1 2.72Å; K661-E669 IonicContact NZ-OE2 2.66Å; K661-E669 PolarHBondContact NZ-OE2 3.21Å; K661-N691 WeakPolarHBondContact CE-OD1 3.44Å
662A96.4Very high93.4Very high0 Ų046 Ų460%026%0.255CS..EExtended strand (participates in β ladder)trans-89.2133.9166.100000107.9I538 V548 F549 L550 E669 S670 F704I538-A662 HydrophobicContact CB-CB 4.48Å; I538-A662 HydrophobicContact CD1-CB 4.17Å; I538-A662 HydrophobicContact CG1-CB 3.9Å; I538-A662 HydrophobicContact CG2-CB 3.92Å; V548-A662 HydrophobicContact CG1-CB 4.26Å; F549-A662 CarbonylContact O-C 3.56Å; F549-A662 WeakPolarHBondContact O-CA 3.23Å; L550-A662 HydrophobicContact CD2-CB 3.9Å; A662-E669 CarbonylContact O-C 3.57Å; A662-S670 PolarHBondContact N-OG 3.21Å; A662-S670 VanDerWaalsContact N-OG 3.11Å; A662-S670 PolarHBondContact O-N 3.46Å; A662-S670 PolarHBondContact O-OG 3.41Å; A662-F704 HydrophobicContact CB-CD2 4.09Å; A662-F704 HydrophobicContact CB-CE2 4.21Å
663I96.4Very high92.6Very high4 Ų441 Ų412%0.02123%0.234CC..EExtended strand (participates in β ladder)trans-133.5136.7-173.7-46-179.2000107.9V548 F549 R551 I615 K661 Q668 E669V548-I663 CarbonylContact C-O 3.6Å; V548-I663 WeakPolarHBondContact CA-O 3.41Å; F549-I663 PolarHBondContact N-O 3.47Å; F549-I663 PolarHBondContact O-N 2.96Å; R551-I663 HydrophobicContact CB-CD1 4.11Å; R551-I663 HydrophobicContact CG-CD1 3.79Å; I615-I663 HydrophobicContact CD1-CB 4.47Å; I615-I663 HydrophobicContact CD1-CG2 4.03Å; K661-I663 HydrophobicContact CB-CG1 4.22Å; I663-Q668 VanDerWaalsContact CA-O 3.29Å; I663-Q668 WeakPolarHBondContact CA-O 3.42Å; I663-E669 HydrophobicContact CG1-CG 4.38Å; I663-E669 HydrophobicContact CG2-CG 4.48Å
664T95.9Very high91.7Very high0 Ų043.6 Ų43.60%026%0.257CS..EExtended strand (participates in β ladder)trans-87.5157.5171.944.90000110.2K540 H547 V548 I615 D666 L667 Q668 F704K540-T664 HydrophobicContact CG-CG2 4.34Å; H547-T664 WeakPolarHBondContact O-CA 3.38Å; V548-T664 HydrophobicContact CG2-CG2 4.18Å; I615-T664 VanDerWaalsContact CD1-O 3.26Å; I615-T664 WeakPolarHBondContact CD1-O 3.09Å; T664-D666 WeakPolarHBondContact CB-OD1 3.1Å; T664-D666 PolarHBondContact O-N 3.18Å; T664-D666 PolarHBondContact OG1-OD1 3.13Å; T664-L667 WeakPolarHBondContact O-CA 3.26Å; T664-L667 PolarHBondContact O-N 2.88Å; T664-Q668 PolarHBondContact N-O 3.08Å; T664-Q668 WeakPolarHBondContact OG1-CA 3.22Å; T664-Q668 WeakPolarHBondContact OG1-CB 3.43Å; T664-Q668 PolarHBondContact OG1-N 3.17Å; T664-Q668 PolarHBondContact OG1-O 2.73Å; T664-Q668 VanDerWaalsContact OG1-O 3.11Å; T664-F704 HydrophobicContact CG2-CE2 4.21Å; T664-F704 HydrophobicContact CG2-CZ 4.19Å
665D90.7Very high91.2Very high61 Ų6149.8 Ų49.833%0.32628%0.28SS..THydrogen-bonded Turntrans-59.2-24.8174.948.811.2000114.2Q546 H547 F549 L667Q546-D665 WeakPolarHBondContact CA-OD2 3.09Å; Q546-D665 WeakPolarHBondContact CG-OD1 3.4Å; H547-D665 IonicContact CD2-OD2 3.21Å; H547-D665 PolarHBondContact N-OD2 3.22Å; H547-D665 PolarHBondContact O-N 3.15Å; H547-D665 VanDerWaalsContact O-N 3.1Å; F549-D665 HydrophobicContact CE2-CB 4.19Å; D665-L667 PolarHBondContact O-N 2.91Å
666D91.3Very high91.2Very high81 Ų8146.2 Ų46.243%0.43324%0.243SC..THydrogen-bonded Turntrans-82.214.2167.970.1-47000114.2Q546 T664 Q668Q546-D666 PolarHBondContact NE2-OD1 2.98Å; T664-D666 WeakPolarHBondContact CB-OD1 3.1Å; T664-D666 PolarHBondContact O-N 3.18Å; T664-D666 PolarHBondContact OG1-OD1 3.13Å; D666-Q668 VanDerWaalsContact C-N 3.3Å; D666-Q668 PolarHBondContact O-N 3.43Å; D666-Q668 WeakPolarHBondContact OD2-CG 3.49Å; D666-Q668 PolarHBondContact OD2-NE2 3.18Å
667L91.4Very high91.1Very high117 Ų11746.9 Ų46.961%0.61324%0.242SC*.  trans6619.2173.5-52.3176.8000115.3I615 T664 D665I615-L667 HydrophobicContact CD1-CD2 4.11Å; T664-L667 WeakPolarHBondContact O-CA 3.26Å; T664-L667 PolarHBondContact O-N 2.88Å; D665-L667 PolarHBondContact O-N 2.91Å
668Q93.6Very high90.9Very high84 Ų8448.1 Ų48.139%0.39325%0.249SC..PPolyproline II helixtrans-70.7134.9166.3-47.11773.200109K540 I663 T664 D666 F704K540-Q668 VanDerWaalsContact NZ-OE1 3.11Å; I663-Q668 VanDerWaalsContact CA-O 3.29Å; I663-Q668 WeakPolarHBondContact CA-O 3.42Å; T664-Q668 PolarHBondContact N-O 3.08Å; T664-Q668 WeakPolarHBondContact OG1-CA 3.22Å; T664-Q668 WeakPolarHBondContact OG1-CB 3.43Å; T664-Q668 PolarHBondContact OG1-N 3.17Å; T664-Q668 PolarHBondContact OG1-O 2.73Å; T664-Q668 VanDerWaalsContact OG1-O 3.11Å; D666-Q668 VanDerWaalsContact C-N 3.3Å; D666-Q668 PolarHBondContact O-N 3.43Å; D666-Q668 WeakPolarHBondContact OD2-CG 3.49Å; D666-Q668 PolarHBondContact OD2-NE2 3.18Å; Q668-F704 HydrophobicContact CB-CE1 4.29Å; Q668-F704 HydrophobicContact CB-CZ 4.03Å; Q668-F704 WeakPolarHBondContact O-CZ 3.39Å
669E93.7Very high90.4Very high101 Ų10156.5 Ų56.547%0.47229%0.286SS..BIsolated β-bridgetrans-103.9147.8176.6-60.5-170.3155.700111.5K661 A662 I663 F704K661-E669 WeakPolarHBondContact CD-OE2 3.4Å; K661-E669 IonicContact NZ-OE1 2.72Å; K661-E669 IonicContact NZ-OE2 2.66Å; K661-E669 PolarHBondContact NZ-OE2 3.21Å; A662-E669 CarbonylContact O-C 3.57Å; I663-E669 HydrophobicContact CG1-CG 4.38Å; I663-E669 HydrophobicContact CG2-CG 4.48Å; E669-F704 VanDerWaalsContact C-CZ 3.45Å
670S92.6Very high89.9Confident14 Ų1461.7 Ų61.710%0.09832%0.322CS..PPolyproline II helixtrans-69.6150.2176.861.90000113.2A662 N692 F704A662-S670 PolarHBondContact N-OG 3.21Å; A662-S670 VanDerWaalsContact N-OG 3.11Å; A662-S670 PolarHBondContact O-N 3.46Å; A662-S670 PolarHBondContact O-OG 3.41Å; S670-N692 PolarHBondContact OG-ND2 2.95Å; S670-F704 WeakPolarHBondContact CA-O 3.16Å
671T87.2Confident89.7Confident68 Ų6867.4 Ų67.442%0.41735%0.352SS..PPolyproline II helixtrans-70.7138.3175.2-570000110.2Q673 N692 F704T671-Q673 PolarHBondContact O-NE2 2.96Å; T671-N692 PolarHBondContact O-OD1 3.31Å; T671-F704 PolarHBondContact N-O 2.87Å
672K84.1Confident89.4Confident107 Ų10769.9 Ų69.947%0.46537%0.372SS..PPolyproline II helixtrans-62.6135.5173.2177.4-168.4165.2176.90110.8T689K672-T689 WeakPolarHBondContact CD-O 3.45Å; K672-T689 WeakPolarHBondContact CE-O 3.17Å; K672-T689 PolarHBondContact NZ-O 3.34Å
673Q78.4Confident89Confident12 Ų1271 Ų716%0.05638%0.379CS..PPolyproline II helixtrans-76147.3175.5-50.3-45.6-37.400114.7T671 N692 Y702 D703 Q706 F708 C709T671-Q673 PolarHBondContact O-NE2 2.96Å; Q673-N692 VanDerWaalsContact CG-OD1 3.29Å; Q673-N692 WeakPolarHBondContact CG-OD1 3.4Å; Q673-N692 PolarHBondContact N-OD1 3.04Å; Q673-N692 PolarHBondContact NE2-OD1 3.02Å; Q673-Y702 HydrophobicContact CG-CD1 3.57Å; Q673-Y702 HydrophobicContact CG-CE1 4.04Å; Q673-D703 PolarHBondContact NE2-O 2.81Å; Q673-D703 VanDerWaalsContact NE2-O 3.14Å; Q673-Q706 PolarHBondContact NE2-O 3.46Å; Q673-Q706 PolarHBondContact OE1-O 2.96Å; Q673-F708 VanDerWaalsContact CD-O 3.29Å; Q673-F708 VanDerWaalsContact OE1-C 3.24Å; Q673-F708 PolarHBondContact OE1-O 2.81Å; Q673-C709 HydrophobicContact CB-CB 4.33Å; Q673-C709 WeakPolarHBondContact CB-SG 3.39Å; Q673-C709 HydrophobicContact CG-CB 3.97Å
674A75.4Confident88.6Confident72 Ų7280.1 Ų80.160%0.59542%0.418SS*.SBendtrans-105.7-37.9179.300000113.9P707A674-P707 HydrophobicContact CB-CB 3.99Å
675K83.7Confident88.1Confident150 Ų15083 Ų8365%0.65243%0.433SS*.EExtended strand (participates in β ladder)trans-139.5118.4-178.6-69.1-178-178.2176.40110.8C709K675-C709 VanDerWaalsContact C-SG 3.56Å; K675-C709 PolarHBondContact O-SG 2.81Å
676C90.5Very high88Confident4 Ų483 Ų833%0.02744%0.437CS..EExtended strand (participates in β ladder)trans-102145.2173.4-53.50000111.3V683 C709 Y711C676-V683 PolarHBondContact O-N 3.33Å; C676-C709 CarbonylContact C-O 3.53Å; C676-C709 VanDerWaalsContact CA-O 3.26Å; C676-C709 WeakPolarHBondContact CA-O 3.41Å; C676-C709 WeakPolarHBondContact CA-SG 3.32Å; C676-C709 HydrophobicContact CB-CB 3.81Å; C676-C709 WeakPolarHBondContact CB-SG 3.33Å; C676-C709 PolarHBondContact N-SG 3.07Å; C676-C709 VanDerWaalsContact N-SG 3.42Å; C676-C709 WeakPolarHBondContact SG-CB 3.32Å; C676-C709 CovalentContact SG-SG 2.01Å; C676-C709 PolarHBondContact SG-SG 2.78Å; C676-Y711 HydrophobicContact CB-CD2 4.07Å; C676-Y711 HydrophobicContact CB-CE2 3.31Å; C676-Y711 PolarHBondContact SG-OH 3.17Å
677V92.9Very high87.9Confident35 Ų3581.4 Ų81.421%0.21243%0.425CS..EExtended strand (participates in β ladder)trans-119.9146.5177.5-62.40000112D681 F708 C709 K710 Y711V677-D681 CarbonylContact C-O 3.56Å; V677-D681 VanDerWaalsContact CA-O 3.26Å; V677-D681 WeakPolarHBondContact CA-O 3.36Å; V677-F708 HydrophobicContact CG2-CE2 4.42Å; V677-C709 PolarHBondContact N-O 2.78Å; V677-K710 HydrophobicContact CG2-CB 4.16Å; V677-K710 HydrophobicContact CG2-CG 4.22Å; V677-K710 CarbonylContact O-C 3.5Å; V677-K710 VanDerWaalsContact O-CA 3.25Å; V677-K710 WeakPolarHBondContact O-CA 3.41Å; V677-Y711 PolarHBondContact O-N 2.74Å
678E91.3Very high87.6Confident50 Ų5084.4 Ų84.423%0.23444%0.436CS..EExtended strand (participates in β ladder)trans-118.3119.1164.3-179.2170.2-176.100107.2S680 D681 V683 R695E678-S680 PolarHBondContact O-N 3.12Å; E678-D681 PolarHBondContact N-O 3.21Å; E678-D681 PolarHBondContact O-N 2.95Å; E678-V683 HydrophobicContact CB-CG2 3.63Å; E678-R695 IonicContact OE2-NH1 3.65Å; E678-R695 PolarHBondContact OE2-NH1 3.13Å
679K86.4Confident87.4Confident175 Ų17581.1 Ų81.176%0.76142%0.422SS*.THydrogen-bonded Turntrans56.8-94-165-54.9175.1-178.7176.70111.5
680S85.6Confident87.2Confident110 Ų11084.1 Ų84.177%0.76944%0.436SS*.THydrogen-bonded Turntrans-127.1-4177.2-56.20000112.9E678E678-S680 PolarHBondContact O-N 3.12Å
681D90.4Very high87.1Confident119 Ų11984.2 Ų84.264%0.63644%0.435SS*.EExtended strand (participates in β ladder)trans-92.3133.7-175.5-62.2-47000110.2V677 E678 V683V677-D681 CarbonylContact C-O 3.56Å; V677-D681 VanDerWaalsContact CA-O 3.26Å; V677-D681 WeakPolarHBondContact CA-O 3.36Å; E678-D681 PolarHBondContact N-O 3.21Å; E678-D681 PolarHBondContact O-N 2.95Å; D681-V683 PolarHBondContact O-N 3.26Å
682V89Confident87.5Confident103 Ų10381 Ų8162%0.62442%0.415SS*.EExtended strand (participates in β ladder)trans-68.4122.3173.7179.80000108.7
683V89.1Confident88Confident24 Ų2476.3 Ų76.315%0.14540%0.395CS..PPolyproline II helixtrans-81.3122.4179.2179.50000109.4W657 C676 E678 D681 L685 Y711W657-V683 HydrophobicContact CH2-CG1 3.95Å; W657-V683 HydrophobicContact CZ2-CG1 4.24Å; C676-V683 PolarHBondContact O-N 3.33Å; E678-V683 HydrophobicContact CB-CG2 3.63Å; D681-V683 PolarHBondContact O-N 3.26Å; V683-L685 PolarHBondContact O-N 2.74Å; V683-Y711 HydrophobicContact CB-CD2 4.3Å; V683-Y711 HydrophobicContact CB-CE2 4.32Å; V683-Y711 HydrophobicContact CG1-CD2 4.38Å; V683-Y711 HydrophobicContact CG1-CE2 4.29Å; V683-Y711 HydrophobicContact CG2-CD2 4Å
684K87.2Confident88.8Confident196 Ų19675.7 Ų75.785%0.85239%0.392SS*.  trans-69.4114.6170.2-175178.2179.3-179.50109
685L86.2Confident89.7Confident59 Ų5975.4 Ų75.431%0.30938%0.376SS..  trans-66.7143.9177.8-61.8176.6000110.7W657 V683 Y687 L693W657-L685 HydrophobicContact CZ3-CD2 4.48Å; V683-L685 PolarHBondContact O-N 2.74Å; L685-Y687 VanDerWaalsContact C-N 3.33Å; L685-Y687 PolarHBondContact O-N 2.96Å; L685-L693 HydrophobicContact CB-CD1 4.14Å; L685-L693 HydrophobicContact CD1-CD1 4.19Å; L685-L693 HydrophobicContact CD2-CD1 3.98Å; L685-L693 HydrophobicContact CG-CD1 4.32Å
686P87.9Confident90.4Very high63 Ų6368.8 Ų68.841%0.40935%0.348SS..SBendtrans-71.1-26-175.131.3-40.9000113.8W657 L693W657-P686 HydrophobicContact CB-CG 4.2Å; W657-P686 HydrophobicContact CD2-CG 3.81Å; W657-P686 HydrophobicContact CG-CB 4.49Å; W657-P686 HydrophobicContact CG-CG 3.62Å; P686-L693 HydrophobicContact CG-CD1 4.5Å
687Y89.3Confident90.6Very high46 Ų4669.4 Ų69.418%0.1836%0.355CS..SBendtrans-163163.1-178.349.3-94.2000110.2H557 T558 A654 W657 E659 L685 T689 L693H557-Y687 AromaticContact CD2-CD2 3.83Å; H557-Y687 AromaticContact NE2-CD2 3.27Å; H557-Y687 VanDerWaalsContact NE2-CD2 3.27Å; H557-Y687 WeakPolarHBondContact NE2-CD2 3.39Å; H557-Y687 AromaticContact NE2-CE2 3.33Å; H557-Y687 VanDerWaalsContact NE2-CE2 3.33Å; H557-Y687 WeakPolarHBondContact NE2-CE2 3.49Å; T558-Y687 HydrophobicContact CG2-CD1 3.66Å; T558-Y687 HydrophobicContact CG2-CD2 3.76Å; T558-Y687 HydrophobicContact CG2-CE1 3.43Å; T558-Y687 VanDerWaalsContact CG2-CE1 3.43Å; T558-Y687 HydrophobicContact CG2-CE2 3.47Å; T558-Y687 VanDerWaalsContact CG2-CE2 3.47Å; T558-Y687 HydrophobicContact CG2-CG 3.84Å; A654-Y687 HydrophobicContact CB-CE1 4.04Å; W657-Y687 HydrophobicContact CB-CE1 4.28Å; E659-Y687 HydrophobicContact CG-CE2 4.22Å; E659-Y687 WeakPolarHBondContact OE1-CE2 3.37Å; L685-Y687 VanDerWaalsContact C-N 3.33Å; L685-Y687 PolarHBondContact O-N 2.96Å; Y687-T689 HydrophobicContact CD2-CG2 4.46Å; Y687-T689 HydrophobicContact CE2-CG2 4.26Å; Y687-L693 HydrophobicContact CD2-CD2 4.49Å; Y687-L693 HydrophobicContact CE2-CD1 4.46Å; Y687-L693 HydrophobicContact CE2-CD2 3.55Å; Y687-L693 WeakPolarHBondContact OH-CD2 3.33Å
688E86.1Confident90.8Very high181 Ų18169.4 Ų69.485%0.84635%0.352SS*.  trans-83.9136.5172.6-65.3-174.6175.600110.6
689T88.6Confident91.1Very high15 Ų1567.4 Ų67.49%0.09234%0.343CS..  trans-146.9159.9174.8172.50000109.6E659 K672 Y687 N691 L693E659-T689 HydrophobicContact CG-CG2 4.23Å; E659-T689 WeakPolarHBondContact OE2-CB 3.34Å; E659-T689 PolarHBondContact OE2-OG1 3.27Å; K672-T689 WeakPolarHBondContact CD-O 3.45Å; K672-T689 WeakPolarHBondContact CE-O 3.17Å; K672-T689 PolarHBondContact NZ-O 3.34Å; Y687-T689 HydrophobicContact CD2-CG2 4.46Å; Y687-T689 HydrophobicContact CE2-CG2 4.26Å; T689-N691 VanDerWaalsContact C-N 3.3Å; T689-N691 WeakPolarHBondContact CG2-O 3.25Å; T689-N691 PolarHBondContact OG1-N 2.68Å; T689-N691 VanDerWaalsContact OG1-N 3.09Å; T689-L693 HydrophobicContact CG2-CD1 3.9Å; T689-L693 HydrophobicContact CG2-CD2 3.84Å; T689-L693 HydrophobicContact CG2-CG 3.64Å
690E88.5Confident91.6Very high164 Ų16459.1 Ų59.177%0.76631%0.307SS*.SBendtrans-80.6-10.3171-65.6-178.2173.500113.2
691N91.9Very high92.1Very high15 Ų1554 Ų548%0.0827%0.271CS..SBendtrans-99.9171.8-175.3-59.2-52.2000112.8W599 E659 K661 T689W599-N691 HydrophobicContact CH2-CB 3.98Å; W599-N691 VanDerWaalsContact CH2-CG 3.44Å; W599-N691 WeakPolarHBondContact CH2-ND2 3.4Å; E659-N691 HydrophobicContact CB-CB 4.07Å; E659-N691 HydrophobicContact CG-CB 4.44Å; E659-N691 PolarHBondContact OE2-ND2 3.16Å; K661-N691 WeakPolarHBondContact CE-OD1 3.44Å; T689-N691 VanDerWaalsContact C-N 3.3Å; T689-N691 WeakPolarHBondContact CG2-O 3.25Å; T689-N691 PolarHBondContact OG1-N 2.68Å; T689-N691 VanDerWaalsContact OG1-N 3.09Å
692N94.2Very high92.3Very high2 Ų248.5 Ų48.51%0.01124%0.241CC..EExtended strand (participates in β ladder)trans-74.6140.2168.3-59.5-51.4000109.8E659 F660 S670 T671 Q673 Y702E659-N692 CarbonylContact C-O 3.59Å; E659-N692 VanDerWaalsContact CA-O 3.29Å; E659-N692 WeakPolarHBondContact CA-O 3.24Å; F660-N692 HydrophobicContact CD1-CB 4.26Å; F660-N692 HydrophobicContact CD2-CB 4.2Å; F660-N692 HydrophobicContact CE1-CB 3.83Å; F660-N692 HydrophobicContact CE2-CB 3.75Å; F660-N692 HydrophobicContact CG-CB 4.43Å; F660-N692 HydrophobicContact CZ-CB 3.55Å; F660-N692 PolarHBondContact N-O 3.06Å; F660-N692 WeakPolarHBondContact O-CB 3.3Å; F660-N692 PolarHBondContact O-N 2.61Å; S670-N692 PolarHBondContact OG-ND2 2.95Å; T671-N692 PolarHBondContact O-OD1 3.31Å; Q673-N692 VanDerWaalsContact CG-OD1 3.29Å; Q673-N692 WeakPolarHBondContact CG-OD1 3.4Å; Q673-N692 PolarHBondContact N-OD1 3.04Å; Q673-N692 PolarHBondContact NE2-OD1 3.02Å; N692-Y702 HydrophobicContact CB-CD1 4.38Å; N692-Y702 HydrophobicContact CB-CE1 4.17Å
693L94.4Very high92.6Very high7 Ų744.4 Ų44.44%0.03722%0.216CC..EExtended strand (participates in β ladder)trans-101.9121.6176.7-76.6171.9000110.6W657 F658 E659 L685 P686 Y687 T689 Y702 Y711W657-L693 HydrophobicContact CE3-CB 4.12Å; W657-L693 HydrophobicContact CZ3-CB 4.37Å; F658-L693 CarbonylContact O-C 3.58Å; F658-L693 WeakPolarHBondContact O-CA 3.39Å; E659-L693 HydrophobicContact CG-CD2 3.55Å; L685-L693 HydrophobicContact CB-CD1 4.14Å; L685-L693 HydrophobicContact CD1-CD1 4.19Å; L685-L693 HydrophobicContact CD2-CD1 3.98Å; L685-L693 HydrophobicContact CG-CD1 4.32Å; P686-L693 HydrophobicContact CG-CD1 4.5Å; Y687-L693 HydrophobicContact CD2-CD2 4.49Å; Y687-L693 HydrophobicContact CE2-CD1 4.46Å; Y687-L693 HydrophobicContact CE2-CD2 3.55Å; Y687-L693 WeakPolarHBondContact OH-CD2 3.33Å; T689-L693 HydrophobicContact CG2-CD1 3.9Å; T689-L693 HydrophobicContact CG2-CD2 3.84Å; T689-L693 HydrophobicContact CG2-CG 3.64Å; L693-Y702 VanDerWaalsContact C-OH 3.27Å; L693-Y702 PolarHBondContact O-OH 2.86Å; L693-Y711 PolarHBondContact O-OH 3.44Å
694G95.5Very high92.8Very high0 Ų043.6 Ų43.60%021%0.21CC..EExtended strand (participates in β ladder)trans-105154.4169.700000112.1W657 F658 Y702W657-G694 WeakPolarHBondContact CA-O 3.26Å; F658-G694 VanDerWaalsContact CD1-O 3.3Å; F658-G694 WeakPolarHBondContact CD1-O 3.28Å; F658-G694 PolarHBondContact N-O 3.38Å; F658-G694 PolarHBondContact O-N 3.4Å; G694-Y702 VanDerWaalsContact CA-OH 3.28Å; G694-Y702 WeakPolarHBondContact CA-OH 3.4Å
695R95.8Very high93.1Very high66 Ų6637.5 Ų37.525%0.24919%0.192CC..EExtended strand (participates in β ladder)trans-110.6124.3177.7-161.9175.8-177.4-171.81.1109.7W657 E678 Y698 N700 Y711W657-R695 HydrophobicContact CD2-CG 4.45Å; W657-R695 HydrophobicContact CE3-CB 4.15Å; W657-R695 HydrophobicContact CE3-CG 4.5Å; W657-R695 HydrophobicContact CH2-CB 4.35Å; W657-R695 HydrophobicContact CH2-CG 4.45Å; W657-R695 HydrophobicContact CZ2-CG 4.4Å; W657-R695 HydrophobicContact CZ3-CB 4.02Å; W657-R695 HydrophobicContact CZ3-CG 4.48Å; E678-R695 IonicContact OE2-NH1 3.65Å; E678-R695 PolarHBondContact OE2-NH1 3.13Å; R695-Y698 HydrophobicContact CB-CD2 3.91Å; R695-Y698 HydrophobicContact CB-CG 4.06Å; R695-Y698 VanDerWaalsContact CD-CE2 3.45Å; R695-Y698 HydrophobicContact CG-CD2 3.51Å; R695-Y698 HydrophobicContact CG-CE2 3.77Å; R695-Y698 HydrophobicContact CG-CG 4.08Å; R695-Y698 VanDerWaalsContact NH1-CZ 3.28Å; R695-Y698 PolarHBondContact NH1-OH 2.96Å; R695-Y698 PolarHBondContact NH2-OH 3.22Å; R695-Y698 WeakPolarHBondContact O-CB 3.32Å; R695-Y698 PolarHBondContact O-N 2.9Å; R695-N700 PolarHBondContact N-OD1 3.35Å; R695-N700 PolarHBondContact O-ND2 2.9Å; R695-N700 PolarHBondContact O-OD1 3.38Å; R695-Y711 HydrophobicContact CB-CD1 4.32Å; R695-Y711 HydrophobicContact CB-CE1 4.49Å
696C97.2Very high93.3Very high11 Ų1140 Ų407%0.07420%0.203CC..THydrogen-bonded Turntrans-68.7132.9179.5-167.60000110.5M648 C650 T653 G656 Y698M648-C696 HydrophobicContact SD-CB 4.25Å; C650-C696 WeakPolarHBondContact CA-SG 3.46Å; C650-C696 HydrophobicContact CB-CB 3.85Å; C650-C696 WeakPolarHBondContact CB-SG 3.43Å; C650-C696 WeakPolarHBondContact SG-CB 3.49Å; C650-C696 CovalentContact SG-SG 2.03Å; C650-C696 PolarHBondContact SG-SG 2.74Å; T653-C696 HydrophobicContact CG2-CB 3.96Å; G656-C696 WeakPolarHBondContact O-CB 3Å; G656-C696 PolarHBondContact O-N 3.13Å; C696-Y698 WeakPolarHBondContact O-CD2 3.44Å
697G95.8Very high93.3Very high17 Ų1740.2 Ų40.218%0.17520%0.204CC..THydrogen-bonded Turntrans84.412.6-174.100000115.2H533 T534H533-G697 CarbonylContact O-C 3.52Å; H533-G697 WeakPolarHBondContact O-CA 3.42Å; T534-G697 PolarHBondContact OG1-N 2.96Å
698Y96.9Very high93.2Very high34 Ų3442.7 Ų42.713%0.13322%0.215CC..EExtended strand (participates in β ladder)trans-124.2158.2-179.4-71.6-111.8000110.4I535 R695 C696 N700 Q712 K713 I714I535-Y698 PolarHBondContact N-O 3.48Å; R695-Y698 HydrophobicContact CB-CD2 3.91Å; R695-Y698 HydrophobicContact CB-CG 4.06Å; R695-Y698 VanDerWaalsContact CD-CE2 3.45Å; R695-Y698 HydrophobicContact CG-CD2 3.51Å; R695-Y698 HydrophobicContact CG-CE2 3.77Å; R695-Y698 HydrophobicContact CG-CG 4.08Å; R695-Y698 VanDerWaalsContact NH1-CZ 3.28Å; R695-Y698 PolarHBondContact NH1-OH 2.96Å; R695-Y698 PolarHBondContact NH2-OH 3.22Å; R695-Y698 WeakPolarHBondContact O-CB 3.32Å; R695-Y698 PolarHBondContact O-N 2.9Å; C696-Y698 WeakPolarHBondContact O-CD2 3.44Å; Y698-N700 PolarHBondContact O-ND2 2.86Å; Y698-Q712 CarbonylContact C-O 3.59Å; Y698-Q712 WeakPolarHBondContact CA-O 3.3Å; Y698-Q712 WeakPolarHBondContact CB-O 3.16Å; Y698-K713 HydrophobicContact CD1-CB 4.31Å; Y698-K713 HydrophobicContact CE1-CB 4.02Å; Y698-I714 VanDerWaalsContact C-CD1 3.49Å
699L96.3Very high93.5Very high9 Ų934 Ų345%0.04718%0.175CC..EExtended strand (participates in β ladder)trans-83.9119.2158.6-172.9166.1000106.8I535 F537 Y634 Y637 V701 Q712 I714I535-L699 HydrophobicContact CB-CB 4.42Å; I535-L699 HydrophobicContact CB-CG 4.22Å; I535-L699 HydrophobicContact CG2-CG 4.27Å; I535-L699 CarbonylContact O-C 3.51Å; I535-L699 WeakPolarHBondContact O-CA 3.45Å; F537-L699 HydrophobicContact CD2-CD2 4.1Å; F537-L699 HydrophobicContact CD2-CG 4.3Å; F537-L699 HydrophobicContact CE2-CD1 4.36Å; Y634-L699 HydrophobicContact CD1-CD1 4.38Å; Y637-L699 HydrophobicContact CE2-CD2 4.11Å; Y637-L699 WeakPolarHBondContact OH-CD2 3.47Å; L699-V701 HydrophobicContact CD2-CG2 3.23Å; L699-Q712 HydrophobicContact CB-CB 4.37Å; L699-Q712 PolarHBondContact N-O 3.16Å; L699-Q712 PolarHBondContact O-N 2.98Å; L699-I714 HydrophobicContact CB-CD1 4.22Å; L699-I714 HydrophobicContact CB-CG1 3.85Å
700N97.2Very high93.8Very high0 Ų036.2 Ų36.20%018%0.183CC..EExtended strand (participates in β ladder)trans-114121.7-175.9-50.5-93.9000108.6I535 V536 F537 R695 Y698 Y702 K710 Y711I535-N700 PolarHBondContact O-N 3.18Å; I535-N700 PolarHBondContact O-ND2 3.3Å; V536-N700 CarbonylContact C-O 3.56Å; V536-N700 WeakPolarHBondContact CA-O 3.08Å; V536-N700 HydrophobicContact CG2-CB 4.32Å; F537-N700 PolarHBondContact N-O 3.07Å; R695-N700 PolarHBondContact N-OD1 3.35Å; R695-N700 PolarHBondContact O-ND2 2.9Å; R695-N700 PolarHBondContact O-OD1 3.38Å; Y698-N700 PolarHBondContact O-ND2 2.86Å; N700-Y702 HydrophobicContact CB-CD2 4.47Å; N700-Y702 HydrophobicContact CB-CE2 3.43Å; N700-Y702 VanDerWaalsContact CB-CE2 3.43Å; N700-K710 CarbonylContact C-O 3.58Å; N700-K710 WeakPolarHBondContact CA-O 3.43Å; N700-Y711 HydrophobicContact CB-CD1 4.25Å; N700-Y711 HydrophobicContact CB-CE1 4.4Å; N700-Y711 WeakPolarHBondContact OD1-CD1 3.23Å; N700-Y711 WeakPolarHBondContact OD1-CE1 3.4Å
701V96.1Very high94.1Very high4 Ų428.5 Ų28.52%0.02415%0.147CC..EExtended strand (participates in β ladder)trans-116.3134.4-176-168.40000109.6F537 Y637 F641 L699 C709 K710F537-V701 HydrophobicContact CB-CG1 4.24Å; F537-V701 CarbonylContact O-C 3.58Å; Y637-V701 HydrophobicContact CD1-CG1 4.24Å; Y637-V701 HydrophobicContact CD2-CG1 4.34Å; Y637-V701 HydrophobicContact CD2-CG2 4.45Å; Y637-V701 HydrophobicContact CE1-CG1 4.29Å; Y637-V701 HydrophobicContact CE1-CG2 3.81Å; Y637-V701 HydrophobicContact CE2-CG1 4.39Å; Y637-V701 HydrophobicContact CE2-CG2 3.71Å; Y637-V701 HydrophobicContact CG-CG1 4.28Å; Y637-V701 WeakPolarHBondContact OH-CG2 3.5Å; F641-V701 HydrophobicContact CE1-CG1 3.7Å; F641-V701 HydrophobicContact CZ-CG1 4.43Å; L699-V701 HydrophobicContact CD2-CG2 3.23Å; V701-C709 CarbonylContact O-C 3.45Å; V701-C709 WeakPolarHBondContact O-CA 3.49Å; V701-K710 HydrophobicContact CB-CB 4.26Å; V701-K710 PolarHBondContact N-O 2.89Å; V701-K710 PolarHBondContact O-N 2.94Å
702Y96.1Very high94.2Very high2 Ų232.1 Ų32.11%0.00816%0.164CC..EExtended strand (participates in β ladder)trans-139.6161.6-179.5-53-101000110.9V536 F537 I538 R539 F660 Q673 N692 L693 G694 N700 C709 Y711V536-Y702 HydrophobicContact CG1-CD2 4.05Å; V536-Y702 HydrophobicContact CG1-CE2 4.01Å; F537-Y702 PolarHBondContact O-N 2.75Å; I538-Y702 HydrophobicContact CD1-CD2 3.8Å; I538-Y702 HydrophobicContact CD1-CG 3.98Å; R539-Y702 PolarHBondContact N-O 3.01Å; F660-Y702 HydrophobicContact CE1-CE1 4.24Å; F660-Y702 AromaticContact CE1-CE2 3.86Å; F660-Y702 HydrophobicContact CE1-CE2 3.86Å; F660-Y702 AromaticContact CE1-CZ 3.69Å; F660-Y702 HydrophobicContact CZ-CD1 4.11Å; F660-Y702 AromaticContact CZ-CD2 3.72Å; F660-Y702 HydrophobicContact CZ-CD2 3.72Å; F660-Y702 AromaticContact CZ-CE1 3.85Å; F660-Y702 HydrophobicContact CZ-CE1 3.85Å; F660-Y702 AromaticContact CZ-CE2 3.41Å; F660-Y702 HydrophobicContact CZ-CE2 3.41Å; F660-Y702 VanDerWaalsContact CZ-CE2 3.41Å; F660-Y702 HydrophobicContact CZ-CG 4.08Å; F660-Y702 AromaticContact CZ-CZ 3.51Å; Q673-Y702 HydrophobicContact CG-CD1 3.57Å; Q673-Y702 HydrophobicContact CG-CE1 4.04Å; N692-Y702 HydrophobicContact CB-CD1 4.38Å; N692-Y702 HydrophobicContact CB-CE1 4.17Å; L693-Y702 VanDerWaalsContact C-OH 3.27Å; L693-Y702 PolarHBondContact O-OH 2.86Å; G694-Y702 VanDerWaalsContact CA-OH 3.28Å; G694-Y702 WeakPolarHBondContact CA-OH 3.4Å; N700-Y702 HydrophobicContact CB-CD2 4.47Å; N700-Y702 HydrophobicContact CB-CE2 3.43Å; N700-Y702 VanDerWaalsContact CB-CE2 3.43Å; Y702-C709 HydrophobicContact CD1-CB 3.66Å; Y702-C709 HydrophobicContact CE1-CB 3.57Å; Y702-Y711 WeakPolarHBondContact OH-CE1 3.27Å
703D94.4Very high94Very high18 Ų1839 Ų3910%0.09619%0.194CC..EExtended strand (participates in β ladder)trans-109.6138.8163.5-171.3-70.5000109.3R539 Q673 S705 Q706R539-D703 HydrophobicContact CB-CB 4.38Å; R539-D703 WeakPolarHBondContact CD-OD2 3.36Å; R539-D703 IonicContact CZ-OD2 2.67Å; R539-D703 IonicContact NH1-OD2 3.78Å; R539-D703 PolarHBondContact NH1-OD2 2.93Å; Q673-D703 PolarHBondContact NE2-O 2.81Å; Q673-D703 VanDerWaalsContact NE2-O 3.14Å; D703-S705 VanDerWaalsContact C-N 3.29Å; D703-S705 PolarHBondContact O-N 2.86Å; D703-S705 PolarHBondContact OD1-N 2.61Å; D703-Q706 HydrophobicContact CB-CB 3.88Å; D703-Q706 HydrophobicContact CB-CG 4.47Å; D703-Q706 PolarHBondContact OD1-N 2.88Å
704F94.2Very high93.6Very high7 Ų743 Ų433%0.03121%0.214CC..SBendtrans-65.5-32.6-176.9-172.6-82.3000112.7I538 R539 K540 A662 T664 Q668 E669 S670 T671I538-F704 HydrophobicContact CG2-CB 4.02Å; I538-F704 HydrophobicContact CG2-CD2 4.08Å; R539-F704 WeakPolarHBondContact O-CB 3.28Å; R539-F704 PolarHBondContact O-N 3.33Å; K540-F704 HydrophobicContact CB-CB 3.85Å; K540-F704 HydrophobicContact CB-CD2 4.12Å; K540-F704 HydrophobicContact CB-CG 4.1Å; K540-F704 HydrophobicContact CD-CB 4.05Å; K540-F704 HydrophobicContact CD-CD1 3.78Å; K540-F704 HydrophobicContact CD-CD2 4.14Å; K540-F704 HydrophobicContact CD-CE1 4.25Å; K540-F704 HydrophobicContact CD-CG 3.73Å; K540-F704 HydrophobicContact CG-CB 4.3Å; K540-F704 HydrophobicContact CG-CD2 4.05Å; K540-F704 HydrophobicContact CG-CG 4.07Å; A662-F704 HydrophobicContact CB-CD2 4.09Å; A662-F704 HydrophobicContact CB-CE2 4.21Å; T664-F704 HydrophobicContact CG2-CE2 4.21Å; T664-F704 HydrophobicContact CG2-CZ 4.19Å; Q668-F704 HydrophobicContact CB-CE1 4.29Å; Q668-F704 HydrophobicContact CB-CZ 4.03Å; Q668-F704 WeakPolarHBondContact O-CZ 3.39Å; E669-F704 VanDerWaalsContact C-CZ 3.45Å; S670-F704 WeakPolarHBondContact CA-O 3.16Å; T671-F704 PolarHBondContact N-O 2.87Å
705S92.4Very high93.5Very high67 Ų6745.2 Ų45.247%0.46923%0.225SC..SBendtrans-115.7-11.4-172.4-62.70000113.7D703D703-S705 VanDerWaalsContact C-N 3.29Å; D703-S705 PolarHBondContact O-N 2.86Å; D703-S705 PolarHBondContact OD1-N 2.61Å
706Q90.6Very high93.4Very high113 Ų11344.1 Ų44.153%0.52822%0.223SC..SBendtrans-109.8145.1178.9-59-62.9-4100111.5Q673 D703 F708Q673-Q706 PolarHBondContact NE2-O 3.46Å; Q673-Q706 PolarHBondContact OE1-O 2.96Å; D703-Q706 HydrophobicContact CB-CB 3.88Å; D703-Q706 HydrophobicContact CB-CG 4.47Å; D703-Q706 PolarHBondContact OD1-N 2.88Å; Q706-F708 PolarHBondContact O-N 3.2Å
707P88.2Confident93.2Very high66 Ų6645.9 Ų45.943%0.42923%0.232SC..SBendtrans-7844.2179.334.9-37.7000113A674A674-P707 HydrophobicContact CB-CB 3.99Å
708F86.6Confident93Very high98 Ų9847.6 Ų47.643%0.4324%0.235SC..EExtended strand (participates in β ladder)trans-107.2136.7176.1173-98.1000114.1Q673 V677 Q706 K710Q673-F708 VanDerWaalsContact CD-O 3.29Å; Q673-F708 VanDerWaalsContact OE1-C 3.24Å; Q673-F708 PolarHBondContact OE1-O 2.81Å; V677-F708 HydrophobicContact CG2-CE2 4.42Å; Q706-F708 PolarHBondContact O-N 3.2Å; F708-K710 HydrophobicContact CE1-CB 4.3Å; F708-K710 HydrophobicContact CZ-CB 3.89Å
709C92.7Very high92.8Very high0 Ų048.4 Ų48.40%024%0.241CC..EExtended strand (participates in β ladder)trans-142.7150.8167.432.90000112.8Q673 K675 C676 V677 V701 Y702Q673-C709 HydrophobicContact CB-CB 4.33Å; Q673-C709 WeakPolarHBondContact CB-SG 3.39Å; Q673-C709 HydrophobicContact CG-CB 3.97Å; K675-C709 VanDerWaalsContact C-SG 3.56Å; K675-C709 PolarHBondContact O-SG 2.81Å; C676-C709 CarbonylContact C-O 3.53Å; C676-C709 VanDerWaalsContact CA-O 3.26Å; C676-C709 WeakPolarHBondContact CA-O 3.41Å; C676-C709 WeakPolarHBondContact CA-SG 3.32Å; C676-C709 HydrophobicContact CB-CB 3.81Å; C676-C709 WeakPolarHBondContact CB-SG 3.33Å; C676-C709 PolarHBondContact N-SG 3.07Å; C676-C709 VanDerWaalsContact N-SG 3.42Å; C676-C709 WeakPolarHBondContact SG-CB 3.32Å; C676-C709 CovalentContact SG-SG 2.01Å; C676-C709 PolarHBondContact SG-SG 2.78Å; V677-C709 PolarHBondContact N-O 2.78Å; V701-C709 CarbonylContact O-C 3.45Å; V701-C709 WeakPolarHBondContact O-CA 3.49Å; Y702-C709 HydrophobicContact CD1-CB 3.66Å; Y702-C709 HydrophobicContact CE1-CB 3.57Å
710K94.5Very high92.6Very high61 Ų6151.1 Ų51.127%0.26525%0.254SS..EExtended strand (participates in β ladder)trans-137138.1174.6178.4178.3177.3-178.70111.6V677 N700 V701 F708V677-K710 HydrophobicContact CG2-CB 4.16Å; V677-K710 HydrophobicContact CG2-CG 4.22Å; V677-K710 CarbonylContact O-C 3.5Å; V677-K710 VanDerWaalsContact O-CA 3.25Å; V677-K710 WeakPolarHBondContact O-CA 3.41Å; N700-K710 CarbonylContact C-O 3.58Å; N700-K710 WeakPolarHBondContact CA-O 3.43Å; V701-K710 HydrophobicContact CB-CB 4.26Å; V701-K710 PolarHBondContact N-O 2.89Å; V701-K710 PolarHBondContact O-N 2.94Å; F708-K710 HydrophobicContact CE1-CB 4.3Å; F708-K710 HydrophobicContact CZ-CB 3.89Å
711Y95Very high92.2Very high1 Ų154.7 Ų54.70%0.00427%0.272CS..EExtended strand (participates in β ladder)trans-109.8140.3171.8-52.9-60.2000110.8W657 C676 V677 V683 L693 R695 N700 Y702W657-Y711 HydrophobicContact CH2-CD2 4.29Å; W657-Y711 AromaticContact CH2-CE2 3.7Å; W657-Y711 HydrophobicContact CH2-CE2 3.7Å; W657-Y711 AromaticContact CH2-CZ 3.96Å; W657-Y711 HydrophobicContact CZ3-CE1 4.12Å; W657-Y711 AromaticContact CZ3-CE2 3.79Å; W657-Y711 HydrophobicContact CZ3-CE2 3.79Å; W657-Y711 AromaticContact CZ3-CZ 3.52Å; W657-Y711 WeakPolarHBondContact CZ3-OH 3.47Å; C676-Y711 HydrophobicContact CB-CD2 4.07Å; C676-Y711 HydrophobicContact CB-CE2 3.31Å; C676-Y711 PolarHBondContact SG-OH 3.17Å; V677-Y711 PolarHBondContact O-N 2.74Å; V683-Y711 HydrophobicContact CB-CD2 4.3Å; V683-Y711 HydrophobicContact CB-CE2 4.32Å; V683-Y711 HydrophobicContact CG1-CD2 4.38Å; V683-Y711 HydrophobicContact CG1-CE2 4.29Å; V683-Y711 HydrophobicContact CG2-CD2 4Å; L693-Y711 PolarHBondContact O-OH 3.44Å; R695-Y711 HydrophobicContact CB-CD1 4.32Å; R695-Y711 HydrophobicContact CB-CE1 4.49Å; N700-Y711 HydrophobicContact CB-CD1 4.25Å; N700-Y711 HydrophobicContact CB-CE1 4.4Å; N700-Y711 WeakPolarHBondContact OD1-CD1 3.23Å; N700-Y711 WeakPolarHBondContact OD1-CE1 3.4Å; Y702-Y711 WeakPolarHBondContact OH-CE1 3.27Å
712Q94.4Very high91.9Very high91 Ų9158.6 Ų58.643%0.42529%0.291SS..EExtended strand (participates in β ladder)trans-140.3130.4173.3175.4172.9-13.600109.1Y698 L699 I714Y698-Q712 CarbonylContact C-O 3.59Å; Y698-Q712 WeakPolarHBondContact CA-O 3.3Å; Y698-Q712 WeakPolarHBondContact CB-O 3.16Å; L699-Q712 HydrophobicContact CB-CB 4.37Å; L699-Q712 PolarHBondContact N-O 3.16Å; L699-Q712 PolarHBondContact O-N 2.98Å; Q712-I714 PolarHBondContact O-N 3.28Å
713K90.2Very high91.6Very high148 Ų14863.3 Ų63.364%0.64332%0.315SS*.EExtended strand (participates in β ladder)trans-66.9132173.2-167.4176.2-179.2-177.40109.7Y698Y698-K713 HydrophobicContact CD1-CB 4.31Å; Y698-K713 HydrophobicContact CE1-CB 4.02Å
714I85.9Confident91.3Very high90 Ų9067.5 Ų67.546%0.46234%0.335SS..  trans-75.90176.7-66.1166000110.7H533 I535 Y698 L699 Q712H533-I714 WeakPolarHBondContact O-CD1 3.49Å; I535-I714 HydrophobicContact CB-CD1 4.24Å; I535-I714 HydrophobicContact CD1-CD1 3.92Å; I535-I714 HydrophobicContact CG1-CD1 3.83Å; Y698-I714 VanDerWaalsContact C-CD1 3.49Å; L699-I714 HydrophobicContact CB-CD1 4.22Å; L699-I714 HydrophobicContact CB-CG1 3.85Å; Q712-I714 PolarHBondContact O-N 3.28Å

Retrieved 714 of 714 residues in 648 ms (Link to these results)