A0A077ZAY9_TRITR Loading...

triacylglycerol lipase

AlphaFold DB , UniProt , Accession A0A077ZAY9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 733 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M76.7Confident89.4Confident50 Ų5011.6 Ų11.625%0.2468%0.076CC..  0165.40-61.1171.6-158.700108.6L29 V30 H32 I172 L251M1-L29 HydrophobicContact CB-CD1 3.93Å; M1-L29 HydrophobicContact CE-CD1 4.13Å; M1-L29 HydrophobicContact CG-CD1 3.93Å; M1-L29 HydrophobicContact SD-CD1 3.5Å; M1-L29 WeakPolarHBondContact SD-CD1 3.44Å; M1-V30 PolarHBondContact N-O 3.1Å; M1-V30 VanDerWaalsContact N-O 3.09Å; M1-H32 PolarHBondContact O-N 3.43Å; M1-I172 HydrophobicContact SD-CD1 4.31Å; M1-L251 HydrophobicContact CE-CD2 3.4Å; M1-L251 VanDerWaalsContact CE-CD2 3.4Å; M1-L251 HydrophobicContact CE-CG 3.71Å; M1-L251 HydrophobicContact SD-CD2 3.64Å
2N89.1Confident89.4Confident16 Ų1611.2 Ų11.29%0.0867%0.074CC..EExtended strand (participates in β ladder)trans-117.4160.7179.7-63.8-27.6000110.3K33 D168 T171 I172N2-K33 VanDerWaalsContact CA-O 3.23Å; N2-K33 WeakPolarHBondContact CA-O 3.47Å; N2-K33 HydrophobicContact CB-CB 4.46Å; N2-K33 WeakPolarHBondContact CB-O 3.37Å; N2-K33 WeakPolarHBondContact OD1-CB 3.42Å; N2-K33 PolarHBondContact OD1-N 2.97Å; N2-K33 PolarHBondContact OD1-O 2.98Å; N2-D168 PolarHBondContact ND2-OD2 2.91Å; N2-T171 HydrophobicContact CB-CG2 4.46Å; N2-T171 WeakPolarHBondContact O-CA 3.39Å; N2-I172 PolarHBondContact O-N 3.44Å
3F92Very high89.6Confident1 Ų110.4 Ų10.40%0.0047%0.069CC..EExtended strand (participates in β ladder)trans-136.3149.2-178.6-82.3-88.5000111.6F5 I22 L29 V31 K33 I34 S35 I172 V174 I183F3-F5 HydrophobicContact CB-CD2 4.28Å; F3-F5 HydrophobicContact CB-CE2 3.81Å; F3-F5 HydrophobicContact CD1-CE2 4.2Å; F3-F5 HydrophobicContact CG-CE2 4.23Å; F3-I22 HydrophobicContact CD1-CD1 4.27Å; F3-I22 HydrophobicContact CE1-CD1 3.61Å; F3-I22 HydrophobicContact CE1-CG1 4.47Å; F3-I22 HydrophobicContact CE2-CD1 4.35Å; F3-I22 HydrophobicContact CZ-CD1 3.65Å; F3-I22 HydrophobicContact CZ-CG1 4.21Å; F3-L29 HydrophobicContact CE2-CD2 3.55Å; F3-L29 HydrophobicContact CE2-CG 4.14Å; F3-L29 HydrophobicContact CZ-CD2 3.56Å; F3-V31 HydrophobicContact CD2-CG1 4.44Å; F3-V31 HydrophobicContact CD2-CG2 4.07Å; F3-V31 HydrophobicContact CE2-CG2 4.14Å; F3-K33 PolarHBondContact N-O 2.87Å; F3-I34 HydrophobicContact CB-CD1 4.11Å; F3-I34 HydrophobicContact CB-CG1 3.87Å; F3-I34 CarbonylContact O-C 3.58Å; F3-I34 VanDerWaalsContact O-CA 3.28Å; F3-I34 WeakPolarHBondContact O-CA 3.39Å; F3-S35 PolarHBondContact O-N 2.8Å; F3-S35 PolarHBondContact O-OG 3.41Å; F3-I172 CarbonylContact C-O 3.56Å; F3-I172 VanDerWaalsContact CA-O 3.28Å; F3-I172 WeakPolarHBondContact CA-O 3.45Å; F3-I172 HydrophobicContact CD1-CB 3.71Å; F3-I172 HydrophobicContact CD1-CG2 3.9Å; F3-I172 HydrophobicContact CE1-CB 3.77Å; F3-I172 HydrophobicContact CE1-CD1 3.96Å; F3-I172 HydrophobicContact CE1-CG1 4.48Å; F3-I172 HydrophobicContact CE1-CG2 3.66Å; F3-I172 HydrophobicContact CE2-CD1 4.31Å; F3-I172 HydrophobicContact CG-CB 4.36Å; F3-I172 HydrophobicContact CZ-CB 4.46Å; F3-I172 HydrophobicContact CZ-CD1 3.82Å; F3-V174 HydrophobicContact CD1-CG2 4.15Å; F3-I183 HydrophobicContact CE1-CD1 4.39Å
4S94.7Very high90Very high0 Ų09.9 Ų9.90%07%0.065CC..EExtended strand (participates in β ladder)trans-128.3129.2170.2-171.40000111.3S35 L164 P165 I172 V174S4-S35 WeakPolarHBondContact CA-O 3.25Å; S4-S35 WeakPolarHBondContact CA-OG 3.25Å; S4-S35 VanDerWaalsContact CB-OG 3.26Å; S4-S35 WeakPolarHBondContact CB-OG 3.15Å; S4-S35 PolarHBondContact OG-OG 2.94Å; S4-L164 WeakPolarHBondContact OG-CD1 3.4Å; S4-P165 VanDerWaalsContact CB-O 3.29Å; S4-P165 WeakPolarHBondContact CB-O 3.34Å; S4-P165 PolarHBondContact OG-O 3.01Å; S4-I172 PolarHBondContact N-O 3.19Å; S4-V174 WeakPolarHBondContact O-CB 3.33Å; S4-V174 PolarHBondContact O-N 2.71Å
5F95.4Very high90.3Very high0 Ų09.2 Ų9.20%06%0.061CC..EExtended strand (participates in β ladder)trans-114119.5-177.2-76.9-101.3000111.3F3 H15 V18 I22 I34 S35 G36 A37 G40 A43 L47 V174F3-F5 HydrophobicContact CB-CD2 4.28Å; F3-F5 HydrophobicContact CB-CE2 3.81Å; F3-F5 HydrophobicContact CD1-CE2 4.2Å; F3-F5 HydrophobicContact CG-CE2 4.23Å; F5-H15 HydrophobicContact CD1-CB 3.98Å; F5-H15 AromaticContact CD1-CE1 3.99Å; F5-H15 AromaticContact CD1-CG 3.74Å; F5-H15 AromaticContact CD1-ND1 3.63Å; F5-H15 HydrophobicContact CE1-CB 4.29Å; F5-V18 HydrophobicContact CE1-CB 4.2Å; F5-V18 HydrophobicContact CE1-CG1 3.78Å; F5-V18 HydrophobicContact CZ-CG1 3.98Å; F5-I22 HydrophobicContact CZ-CD1 4.26Å; F5-I34 HydrophobicContact CD2-CD1 3.9Å; F5-I34 HydrophobicContact CD2-CG1 3.97Å; F5-I34 HydrophobicContact CE2-CD1 3.57Å; F5-I34 HydrophobicContact CE2-CG1 4.08Å; F5-S35 PolarHBondContact N-O 2.83Å; F5-G36 WeakPolarHBondContact O-CA 3.19Å; F5-A37 PolarHBondContact O-N 2.89Å; F5-G40 WeakPolarHBondContact CB-O 3.44Å; F5-A43 HydrophobicContact CD1-CB 4.17Å; F5-L47 HydrophobicContact CE2-CD1 3.94Å; F5-L47 HydrophobicContact CZ-CD1 3.67Å; F5-V174 HydrophobicContact CD1-CB 3.92Å; F5-V174 HydrophobicContact CD1-CG1 3.91Å; F5-V174 HydrophobicContact CD1-CG2 4.24Å; F5-V174 HydrophobicContact CD2-CG2 4.42Å; F5-V174 HydrophobicContact CE1-CB 4.09Å; F5-V174 HydrophobicContact CE1-CG1 3.88Å; F5-V174 HydrophobicContact CE1-CG2 4.01Å; F5-V174 HydrophobicContact CE2-CG2 4.18Å; F5-V174 HydrophobicContact CG-CB 4.23Å; F5-V174 HydrophobicContact CG-CG2 4.44Å; F5-V174 HydrophobicContact CZ-CG2 3.97Å
6S94.4Very high90.5Very high0 Ų08.9 Ų8.90%06%0.058CC..  trans-67.7152-173.391.30000113.6C8 H15 G40 N163 V174 P176S6-C8 PolarHBondContact O-SG 3.43Å; S6-H15 PolarHBondContact O-NE2 3.49Å; S6-G40 WeakPolarHBondContact O-CA 3.04Å; S6-G40 PolarHBondContact O-N 2.97Å; S6-N163 CarbonylContact C-O 3.23Å; S6-N163 WeakPolarHBondContact CA-O 3.49Å; S6-V174 PolarHBondContact N-O 3.17Å; S6-P176 WeakPolarHBondContact OG-CD 3.24Å
7G90.8Very high90.6Very high4 Ų48.4 Ų8.44%0.0416%0.055CC..  trans-61.2141.9161.700000111.3A37 N163G7-A37 WeakPolarHBondContact CA-O 3.26Å; G7-A37 PolarHBondContact N-O 2.92Å; G7-N163 WeakPolarHBondContact CA-OD1 3.23Å; G7-N163 PolarHBondContact N-O 3.44Å; G7-N163 PolarHBondContact N-OD1 2.81Å; G7-N163 PolarHBondContact O-ND2 2.9Å
8C87.7Confident90.7Very high7 Ų77.9 Ų7.95%0.0475%0.052CC..  trans-164.4-1.8-164.657.30000116.7S6 F10 L11 H15 P176 A216S6-C8 PolarHBondContact O-SG 3.43Å; C8-F10 PolarHBondContact O-N 3.21Å; C8-L11 HydrophobicContact CB-CB 4.05Å; C8-L11 WeakPolarHBondContact O-CB 3.34Å; C8-L11 PolarHBondContact O-N 3.08Å; C8-H15 PolarHBondContact SG-CD2 3.44Å; C8-P176 HydrophobicContact CB-CG 3.55Å; C8-A216 WeakPolarHBondContact O-CB 3.25Å
9G87Confident90.8Very high31 Ų317.6 Ų7.632%0.325%0.05SC..G310 helixtrans52.3-128.1-176.800000113.2L11 G12G9-L11 PolarHBondContact O-N 3.31Å; G9-G12 PolarHBondContact O-N 2.81Å; G9-G12 VanDerWaalsContact O-N 3.14Å
10F86.7Confident90.8Very high14 Ų147.4 Ų7.46%0.0615%0.049CC..G310 helixtrans-67.4-12.3-180-78.5-72.1000114.9C8 G12 V63 S64 A67 P74 F79 Y142 A216 P219C8-F10 PolarHBondContact O-N 3.21Å; F10-G12 PolarHBondContact O-N 3.3Å; F10-V63 HydrophobicContact CE1-CB 4.25Å; F10-V63 HydrophobicContact CE1-CG1 3.78Å; F10-V63 HydrophobicContact CZ-CG1 3.94Å; F10-S64 VanDerWaalsContact CD1-OG 3.24Å; F10-S64 WeakPolarHBondContact CD1-OG 3.34Å; F10-S64 WeakPolarHBondContact CE1-OG 3.18Å; F10-A67 HydrophobicContact CZ-CB 4.1Å; F10-P74 HydrophobicContact CE2-CG 3.99Å; F10-F79 HydrophobicContact CZ-CZ 4.37Å; F10-Y142 WeakPolarHBondContact CD2-OH 3.36Å; F10-Y142 WeakPolarHBondContact CE2-OH 3.44Å; F10-A216 PolarHBondContact N-O 3.29Å; F10-P219 HydrophobicContact CB-CB 4.15Å; F10-P219 HydrophobicContact CD1-CB 3.8Å; F10-P219 HydrophobicContact CD1-CG 4.08Å; F10-P219 HydrophobicContact CD2-CB 4.09Å; F10-P219 HydrophobicContact CD2-CG 3.84Å; F10-P219 HydrophobicContact CE1-CB 4.17Å; F10-P219 HydrophobicContact CE1-CG 4.01Å; F10-P219 HydrophobicContact CE2-CB 4.42Å; F10-P219 HydrophobicContact CE2-CG 3.75Å; F10-P219 HydrophobicContact CG-CB 3.75Å; F10-P219 HydrophobicContact CG-CG 3.99Å; F10-P219 HydrophobicContact CZ-CB 4.46Å; F10-P219 HydrophobicContact CZ-CG 3.84Å
11L88.9Confident90.7Very high5 Ų57 Ų73%0.0265%0.046CC..G310 helixtrans-72.80169.6-78.6-179.8000113.9C8 G9 I13 Y14 P176 F177 R212 V215 A216 M228C8-L11 HydrophobicContact CB-CB 4.05Å; C8-L11 WeakPolarHBondContact O-CB 3.34Å; C8-L11 PolarHBondContact O-N 3.08Å; G9-L11 PolarHBondContact O-N 3.31Å; L11-I13 PolarHBondContact O-N 3.09Å; L11-Y14 VanDerWaalsContact O-CB 3.3Å; L11-Y14 WeakPolarHBondContact O-CB 3.5Å; L11-Y14 PolarHBondContact O-N 2.78Å; L11-P176 HydrophobicContact CB-CB 4.15Å; L11-P176 HydrophobicContact CB-CG 4.1Å; L11-P176 HydrophobicContact CD1-CB 4.22Å; L11-P176 HydrophobicContact CD1-CG 4.32Å; L11-F177 HydrophobicContact CD1-CE1 3.93Å; L11-F177 HydrophobicContact CD1-CZ 4.24Å; L11-R212 HydrophobicContact CD1-CB 3.73Å; L11-R212 HydrophobicContact CD1-CG 4.16Å; L11-R212 VanDerWaalsContact CD1-O 3.27Å; L11-R212 WeakPolarHBondContact CD1-O 3.11Å; L11-V215 HydrophobicContact CD1-CG2 4.26Å; L11-V215 HydrophobicContact CD2-CG2 3.77Å; L11-V215 HydrophobicContact CG-CG2 4.07Å; L11-A216 HydrophobicContact CD1-CB 4.18Å; L11-A216 HydrophobicContact CG-CB 4.22Å; L11-M228 HydrophobicContact CD2-CE 4.33Å; L11-M228 HydrophobicContact CD2-CG 4.35Å; L11-M228 HydrophobicContact CD2-SD 3.51Å; L11-M228 VanDerWaalsContact CD2-SD 3.51Å
12G89.3Confident91.2Very high6 Ų65 Ų56%0.0624%0.036CC..Hα-helixtrans-54.3-17171.700000114.6G9 F10 Y14 H15 V16G9-G12 PolarHBondContact O-N 2.81Å; G9-G12 VanDerWaalsContact O-N 3.14Å; F10-G12 PolarHBondContact O-N 3.3Å; G12-Y14 VanDerWaalsContact C-N 3.28Å; G12-Y14 PolarHBondContact O-N 3.09Å; G12-H15 WeakPolarHBondContact O-CB 3.29Å; G12-H15 PolarHBondContact O-N 3.44Å; G12-H15 VanDerWaalsContact O-N 3.17Å; G12-V16 PolarHBondContact O-N 3.08Å; G12-V16 VanDerWaalsContact O-N 3.15Å
13I91.7Very high90.9Very high1 Ų17.5 Ų7.51%0.0055%0.047CC..Hα-helixtrans-62.7-29.8170.3-16169.8000113.4L11 V16 G17 I60 L61 M225 M228 C229 L341L11-I13 PolarHBondContact O-N 3.09Å; I13-V16 WeakPolarHBondContact O-CB 3.47Å; I13-V16 PolarHBondContact O-N 3.03Å; I13-G17 PolarHBondContact O-N 3.29Å; I13-I60 HydrophobicContact CB-CG2 4.2Å; I13-I60 HydrophobicContact CD1-CG2 4.16Å; I13-L61 HydrophobicContact CD1-CG 4.49Å; I13-M225 HydrophobicContact CB-CE 3.95Å; I13-M225 HydrophobicContact CG1-CB 4.29Å; I13-M225 HydrophobicContact CG1-CE 4.38Å; I13-M225 HydrophobicContact CG2-CB 4.19Å; I13-M225 HydrophobicContact CG2-CE 3.93Å; I13-M228 HydrophobicContact CG2-CB 4.08Å; I13-C229 HydrophobicContact CG1-CB 3.94Å; I13-L341 HydrophobicContact CD1-CD2 4.41Å
14Y94.8Very high90.4Very high3 Ų311.3 Ų11.31%0.0126%0.064CC..Hα-helixtrans-63.1-45.4170.8174.5-87.3000110.6L11 G12 V16 G17 V18 V174 S175 P176 I183 C184 P185 Q231 G232 D235L11-Y14 VanDerWaalsContact O-CB 3.3Å; L11-Y14 WeakPolarHBondContact O-CB 3.5Å; L11-Y14 PolarHBondContact O-N 2.78Å; G12-Y14 VanDerWaalsContact C-N 3.28Å; G12-Y14 PolarHBondContact O-N 3.09Å; Y14-V16 VanDerWaalsContact C-N 3.26Å; Y14-V16 PolarHBondContact O-N 3.46Å; Y14-G17 WeakPolarHBondContact O-CA 3.42Å; Y14-G17 PolarHBondContact O-N 3.34Å; Y14-V18 HydrophobicContact CD1-CG2 3.94Å; Y14-V18 HydrophobicContact CE1-CG2 3.62Å; Y14-V18 PolarHBondContact O-N 3.41Å; Y14-V174 HydrophobicContact CE1-CG1 4.23Å; Y14-S175 WeakPolarHBondContact CE1-O 3.42Å; Y14-P176 HydrophobicContact CD1-CB 3.63Å; Y14-P176 HydrophobicContact CD2-CB 4.32Å; Y14-P176 HydrophobicContact CE1-CB 4.23Å; Y14-P176 HydrophobicContact CG-CB 3.69Å; Y14-I183 PolarHBondContact OH-O 2.7Å; Y14-C184 WeakPolarHBondContact OH-CA 3.34Å; Y14-P185 HydrophobicContact CE2-CG 3.77Å; Y14-Q231 HydrophobicContact CE2-CG 4.16Å; Y14-G232 VanDerWaalsContact CD2-CA 3.43Å; Y14-D235 PolarHBondContact OH-OD2 2.8Å
15H94.8Very high89.6Confident0 Ų011.6 Ų11.60%07%0.066CC..Hα-helixtrans-64.3-28177.5-65.9-33.1000112.8F5 S6 C8 G12 G17 V18 A19 A43F5-H15 HydrophobicContact CD1-CB 3.98Å; F5-H15 AromaticContact CD1-CE1 3.99Å; F5-H15 AromaticContact CD1-CG 3.74Å; F5-H15 AromaticContact CD1-ND1 3.63Å; F5-H15 HydrophobicContact CE1-CB 4.29Å; S6-H15 PolarHBondContact O-NE2 3.49Å; C8-H15 PolarHBondContact SG-CD2 3.44Å; G12-H15 WeakPolarHBondContact O-CB 3.29Å; G12-H15 PolarHBondContact O-N 3.44Å; G12-H15 VanDerWaalsContact O-N 3.17Å; H15-G17 VanDerWaalsContact C-N 3.35Å; H15-V18 PolarHBondContact O-N 3.03Å; H15-A19 VanDerWaalsContact O-CB 3.27Å; H15-A19 WeakPolarHBondContact O-CB 3.42Å; H15-A19 PolarHBondContact O-N 3.09Å; H15-A43 HydrophobicContact CB-CB 3.59Å
16V93.1Very high88.7Confident4 Ų411.8 Ų11.82%0.0247%0.067CC..Hα-helixtrans-65.2-38.7169176.60000111.3G12 I13 Y14 A20 V56 C57 I60 V337G12-V16 PolarHBondContact O-N 3.08Å; G12-V16 VanDerWaalsContact O-N 3.15Å; I13-V16 WeakPolarHBondContact O-CB 3.47Å; I13-V16 PolarHBondContact O-N 3.03Å; Y14-V16 VanDerWaalsContact C-N 3.26Å; Y14-V16 PolarHBondContact O-N 3.46Å; V16-A20 VanDerWaalsContact O-CB 3.25Å; V16-A20 WeakPolarHBondContact O-CB 3.36Å; V16-A20 PolarHBondContact O-N 3.28Å; V16-V56 HydrophobicContact CG2-CG1 4.1Å; V16-C57 HydrophobicContact CG1-CB 4.13Å; V16-I60 HydrophobicContact CG2-CD1 3.61Å; V16-V337 HydrophobicContact CG1-CG1 4.26Å
17G92.8Very high87.6Confident0 Ų015.4 Ų15.40%09%0.09CC..Hα-helixtrans-61.4-46.2171.900000112.7I13 Y14 H15 A20 A21 C229 F233I13-G17 PolarHBondContact O-N 3.29Å; Y14-G17 WeakPolarHBondContact O-CA 3.42Å; Y14-G17 PolarHBondContact O-N 3.34Å; H15-G17 VanDerWaalsContact C-N 3.35Å; G17-A20 WeakPolarHBondContact O-CB 3.38Å; G17-A20 PolarHBondContact O-N 2.92Å; G17-A21 PolarHBondContact O-N 3.33Å; G17-C229 VanDerWaalsContact CA-O 3.31Å; G17-C229 WeakPolarHBondContact CA-O 3.48Å; G17-F233 WeakPolarHBondContact O-CA 2.78Å
18V93.2Very high86.3Confident0 Ų018.2 Ų18.20%011%0.105CC..Hα-helixtrans-59.9-51.5175175.30000111.1F5 Y14 H15 A20 A21 I22 V174 I183 G232 T236F5-V18 HydrophobicContact CE1-CB 4.2Å; F5-V18 HydrophobicContact CE1-CG1 3.78Å; F5-V18 HydrophobicContact CZ-CG1 3.98Å; Y14-V18 HydrophobicContact CD1-CG2 3.94Å; Y14-V18 HydrophobicContact CE1-CG2 3.62Å; Y14-V18 PolarHBondContact O-N 3.41Å; H15-V18 PolarHBondContact O-N 3.03Å; V18-A20 PolarHBondContact O-N 3.2Å; V18-A21 PolarHBondContact O-N 2.92Å; V18-A21 VanDerWaalsContact O-N 3.15Å; V18-I22 HydrophobicContact CG1-CD1 3.83Å; V18-I22 HydrophobicContact CG1-CG1 4.49Å; V18-I22 WeakPolarHBondContact O-CG1 3.38Å; V18-I22 PolarHBondContact O-N 3.36Å; V18-V174 HydrophobicContact CB-CG1 4.23Å; V18-V174 HydrophobicContact CG1-CG1 3.86Å; V18-V174 HydrophobicContact CG1-CG2 4.25Å; V18-V174 HydrophobicContact CG2-CG1 3.76Å; V18-I183 HydrophobicContact CG1-CD1 4.42Å; V18-I183 HydrophobicContact CG1-CG2 4.45Å; V18-I183 HydrophobicContact CG2-CG2 4.06Å; V18-G232 WeakPolarHBondContact CG2-O 3.19Å; V18-T236 WeakPolarHBondContact CA-OG1 3.45Å; V18-T236 HydrophobicContact CG1-CG2 4.48Å; V18-T236 WeakPolarHBondContact CG1-OG1 3.17Å; V18-T236 WeakPolarHBondContact CG2-OG1 3.28Å
19A92.2Very high85.5Confident2 Ų218.8 Ų18.82%0.01711%0.107CC..Hα-helixtrans-59.1-35.6177.700000112.5H15 K23 L47 L53H15-A19 VanDerWaalsContact O-CB 3.27Å; H15-A19 WeakPolarHBondContact O-CB 3.42Å; H15-A19 PolarHBondContact O-N 3.09Å; A19-K23 WeakPolarHBondContact O-CB 3.23Å; A19-K23 PolarHBondContact O-N 3.15Å; A19-L47 HydrophobicContact CB-CD1 4.01Å; A19-L47 HydrophobicContact CB-CD2 3.81Å; A19-L47 HydrophobicContact CB-CG 3.89Å; A19-L53 HydrophobicContact CB-CD1 4.16Å; A19-L53 HydrophobicContact CB-CD2 4.07Å
20A90.9Very high84.2Confident3 Ų321.6 Ų21.63%0.02512%0.118CC..Hα-helixtrans-67.4-42.8175.500000112.5V16 G17 V18 K23 E24 L53 F233 P334V16-A20 VanDerWaalsContact O-CB 3.25Å; V16-A20 WeakPolarHBondContact O-CB 3.36Å; V16-A20 PolarHBondContact O-N 3.28Å; G17-A20 WeakPolarHBondContact O-CB 3.38Å; G17-A20 PolarHBondContact O-N 2.92Å; V18-A20 PolarHBondContact O-N 3.2Å; A20-K23 PolarHBondContact O-N 3.45Å; A20-E24 WeakPolarHBondContact O-CB 3.47Å; A20-E24 PolarHBondContact O-N 2.86Å; A20-L53 HydrophobicContact CB-CD1 4.08Å; A20-F233 HydrophobicContact CB-CD2 4.03Å; A20-F233 HydrophobicContact CB-CE2 4.4Å; A20-P334 HydrophobicContact CB-CG 4.02Å
21A88.2Confident83.5Confident0 Ų022 Ų220%012%0.122CC..Hα-helixtrans-66.9-43.7177.300000112.1G17 V18 K23 E24 Y25 F233 T236G17-A21 PolarHBondContact O-N 3.33Å; V18-A21 PolarHBondContact O-N 2.92Å; V18-A21 VanDerWaalsContact O-N 3.15Å; A21-K23 PolarHBondContact O-N 2.89Å; A21-E24 PolarHBondContact O-N 3.06Å; A21-Y25 WeakPolarHBondContact O-CD2 3.49Å; A21-Y25 PolarHBondContact O-N 2.95Å; A21-F233 HydrophobicContact CB-CD2 3.62Å; A21-F233 HydrophobicContact CB-CE2 4.06Å; A21-F233 HydrophobicContact CB-CG 4.13Å; A21-T236 HydrophobicContact CB-CG2 3.5Å; A21-T236 VanDerWaalsContact CB-CG2 3.5Å
22I86.8Confident83.1Confident7 Ų727.1 Ų27.14%0.03615%0.145CC..Hα-helixtrans-57.8-49.9173.7-64.1166.4000110F3 F5 V18 E24 A26 L29 T236F3-I22 HydrophobicContact CD1-CD1 4.27Å; F3-I22 HydrophobicContact CE1-CD1 3.61Å; F3-I22 HydrophobicContact CE1-CG1 4.47Å; F3-I22 HydrophobicContact CE2-CD1 4.35Å; F3-I22 HydrophobicContact CZ-CD1 3.65Å; F3-I22 HydrophobicContact CZ-CG1 4.21Å; F5-I22 HydrophobicContact CZ-CD1 4.26Å; V18-I22 HydrophobicContact CG1-CD1 3.83Å; V18-I22 HydrophobicContact CG1-CG1 4.49Å; V18-I22 WeakPolarHBondContact O-CG1 3.38Å; V18-I22 PolarHBondContact O-N 3.36Å; I22-E24 PolarHBondContact O-N 2.73Å; I22-A26 CarbonylContact O-C 3.48Å; I22-A26 VanDerWaalsContact O-C 3.23Å; I22-A26 WeakPolarHBondContact O-CA 3.45Å; I22-A26 PolarHBondContact O-N 3.23Å; I22-L29 HydrophobicContact CG2-CD2 4.45Å; I22-T236 HydrophobicContact CG1-CG2 4.03Å
23K84.4Confident83.2Confident70 Ų7031.1 Ų31.130%0.30416%0.161SC..Hα-helixtrans-69.4-27.2-175.1-168.2169.3-171.9162.70114.3A19 A20 A21 N50 L51 L53A19-K23 WeakPolarHBondContact O-CB 3.23Å; A19-K23 PolarHBondContact O-N 3.15Å; A20-K23 PolarHBondContact O-N 3.45Å; A21-K23 PolarHBondContact O-N 2.89Å; K23-N50 WeakPolarHBondContact CE-OD1 3.26Å; K23-N50 PolarHBondContact NZ-O 3.3Å; K23-N50 PolarHBondContact NZ-OD1 3.4Å; K23-L51 PolarHBondContact NZ-O 3.24Å; K23-L53 HydrophobicContact CB-CD1 4.36Å; K23-L53 HydrophobicContact CD-CD1 3.91Å; K23-L53 HydrophobicContact CD-CG 4.33Å
24E81.4Confident83.3Confident80 Ų8031 Ų3137%0.37416%0.16SC..Hα-helixtrans-88.9-40.1178-174.1178.1-177.900113.2A20 A21 I22A20-E24 WeakPolarHBondContact O-CB 3.47Å; A20-E24 PolarHBondContact O-N 2.86Å; A21-E24 PolarHBondContact O-N 3.06Å; I22-E24 PolarHBondContact O-N 2.73Å
25Y77.5Confident83.3Confident7 Ų730.9 Ų30.93%0.02716%0.16CC..Hα-helixtrans-105.4-29.7-170-65.1-89.8000114.2A21 P27 F233 L237 L254 I255 S256 A328 K331A21-Y25 WeakPolarHBondContact O-CD2 3.49Å; A21-Y25 PolarHBondContact O-N 2.95Å; Y25-P27 VanDerWaalsContact O-CD 3.3Å; Y25-P27 WeakPolarHBondContact O-CD 3.31Å; Y25-F233 HydrophobicContact CE2-CE2 4.14Å; Y25-F233 AromaticContact CE2-CZ 3.72Å; Y25-F233 HydrophobicContact CE2-CZ 3.72Å; Y25-L237 HydrophobicContact CD1-CD2 4.08Å; Y25-L237 HydrophobicContact CD2-CD2 3.61Å; Y25-L237 HydrophobicContact CE1-CD2 4.4Å; Y25-L237 HydrophobicContact CE2-CD2 3.98Å; Y25-L237 HydrophobicContact CG-CD2 3.69Å; Y25-L254 VanDerWaalsContact O-O 3.09Å; Y25-I255 HydrophobicContact CD1-CG2 4.39Å; Y25-I255 WeakPolarHBondContact O-CA 3.36Å; Y25-S256 PolarHBondContact O-N 2.61Å; Y25-A328 HydrophobicContact CD1-CB 3.86Å; Y25-A328 HydrophobicContact CE1-CB 3.28Å; Y25-K331 VanDerWaalsContact OH-CD 3.24Å; Y25-K331 WeakPolarHBondContact OH-CD 3.31Å
26A75.4Confident83.4Confident3 Ų330.9 Ų30.93%0.02516%0.16CC..  trans-117.450.7-179.700000112.8I22 D28 L29 L240 L254I22-A26 CarbonylContact O-C 3.48Å; I22-A26 VanDerWaalsContact O-C 3.23Å; I22-A26 WeakPolarHBondContact O-CA 3.45Å; I22-A26 PolarHBondContact O-N 3.23Å; A26-D28 PolarHBondContact O-N 3.1Å; A26-L29 HydrophobicContact CB-CB 3.99Å; A26-L29 HydrophobicContact CB-CD2 4.21Å; A26-L29 WeakPolarHBondContact O-CB 3.4Å; A26-L29 PolarHBondContact O-N 3.18Å; A26-L240 HydrophobicContact CB-CD1 4.23Å; A26-L240 HydrophobicContact CB-CD2 4.24Å; A26-L254 VanDerWaalsContact CA-O 3.27Å; A26-L254 WeakPolarHBondContact CA-O 3.36Å; A26-L254 HydrophobicContact CB-CD2 4.44Å; A26-L254 VanDerWaalsContact CB-O 3.26Å; A26-L254 WeakPolarHBondContact CB-O 3.38Å
27P71.3Confident83.5Confident76 Ų7630.7 Ų30.749%0.49416%0.159SC..THydrogen-bonded Turntrans-66.9-23.7-177.830.7-37.2000113.5Y25 L29Y25-P27 VanDerWaalsContact O-CD 3.3Å; Y25-P27 WeakPolarHBondContact O-CD 3.31Å; P27-L29 PolarHBondContact O-N 3.09Å
28D64.6Low83.5Confident63 Ų6331 Ų3134%0.33716%0.16SC..THydrogen-bonded Turntrans-74.4-8.8174-61.3-22.2000112.4A26 V30 S256 R264A26-D28 PolarHBondContact O-N 3.1Å; D28-V30 VanDerWaalsContact C-N 3.35Å; D28-V30 PolarHBondContact O-N 2.81Å; D28-S256 VanDerWaalsContact OD2-CB 3.27Å; D28-S256 WeakPolarHBondContact OD2-CB 3.35Å; D28-S256 PolarHBondContact OD2-OG 2.7Å; D28-R264 IonicContact OD2-NH1 3.26Å
29L69.9Low83.4Confident20 Ų2031.5 Ų31.511%0.10517%0.166CC..  trans-75.287.7-179-173.254.8000110M1 F3 I22 A26 P27 V31 L254M1-L29 HydrophobicContact CB-CD1 3.93Å; M1-L29 HydrophobicContact CE-CD1 4.13Å; M1-L29 HydrophobicContact CG-CD1 3.93Å; M1-L29 HydrophobicContact SD-CD1 3.5Å; M1-L29 WeakPolarHBondContact SD-CD1 3.44Å; F3-L29 HydrophobicContact CE2-CD2 3.55Å; F3-L29 HydrophobicContact CE2-CG 4.14Å; F3-L29 HydrophobicContact CZ-CD2 3.56Å; I22-L29 HydrophobicContact CG2-CD2 4.45Å; A26-L29 HydrophobicContact CB-CB 3.99Å; A26-L29 HydrophobicContact CB-CD2 4.21Å; A26-L29 WeakPolarHBondContact O-CB 3.4Å; A26-L29 PolarHBondContact O-N 3.18Å; P27-L29 PolarHBondContact O-N 3.09Å; L29-V31 PolarHBondContact O-N 3.08Å; L29-L254 HydrophobicContact CD1-CD2 3.96Å; L29-L254 HydrophobicContact CD2-CD2 3.91Å; L29-L254 HydrophobicContact CG-CD2 4.38Å
30V60.1Low83.5Confident89 Ų8931.4 Ų31.454%0.53917%0.165SC..  trans-59.7105.8173.4-173.60000108.6M1 D28 H32M1-V30 PolarHBondContact N-O 3.1Å; M1-V30 VanDerWaalsContact N-O 3.09Å; D28-V30 VanDerWaalsContact C-N 3.35Å; D28-V30 PolarHBondContact O-N 2.81Å; V30-H32 WeakPolarHBondContact CG1-NE2 3.2Å; V30-H32 PolarHBondContact O-CD2 3.43Å; V30-H32 PolarHBondContact O-N 3.08Å
31V72.1Confident83.7Confident24 Ų2431.3 Ų31.315%0.14516%0.164CC..  trans-76.494.7167.9-177.50000106.4F3 L29 I34 I48F3-V31 HydrophobicContact CD2-CG1 4.44Å; F3-V31 HydrophobicContact CD2-CG2 4.07Å; F3-V31 HydrophobicContact CE2-CG2 4.14Å; L29-V31 PolarHBondContact O-N 3.08Å; V31-I34 HydrophobicContact CG1-CB 3.86Å; V31-I34 HydrophobicContact CG1-CD1 4.11Å; V31-I34 HydrophobicContact CG1-CG1 4.45Å; V31-I48 HydrophobicContact CB-CD1 4.49Å; V31-I48 HydrophobicContact CG1-CD1 3.93Å
32H80.1Confident83.9Confident111 Ų11133.5 Ų33.551%0.51418%0.175SC..  trans-73.4-47.8179.9-68.3-105000109.8M1 V30 R104M1-H32 PolarHBondContact O-N 3.43Å; V30-H32 WeakPolarHBondContact CG1-NE2 3.2Å; V30-H32 PolarHBondContact O-CD2 3.43Å; V30-H32 PolarHBondContact O-N 3.08Å; H32-R104 WeakPolarHBondContact O-CB 3.11Å; H32-R104 WeakPolarHBondContact O-CG 3.21Å
33K91.5Very high84.2Confident90 Ų9033.4 Ų33.439%0.39118%0.176SC..  trans-131.4149172.6-54.5176.4179.3174.60110.2N2 F3 R104 F106 L167N2-K33 VanDerWaalsContact CA-O 3.23Å; N2-K33 WeakPolarHBondContact CA-O 3.47Å; N2-K33 HydrophobicContact CB-CB 4.46Å; N2-K33 WeakPolarHBondContact CB-O 3.37Å; N2-K33 WeakPolarHBondContact OD1-CB 3.42Å; N2-K33 PolarHBondContact OD1-N 2.97Å; N2-K33 PolarHBondContact OD1-O 2.98Å; F3-K33 PolarHBondContact N-O 2.87Å; K33-R104 CarbonylContact C-O 3.57Å; K33-R104 VanDerWaalsContact CA-O 3.26Å; K33-R104 WeakPolarHBondContact CA-O 3.33Å; K33-F106 HydrophobicContact CB-CD2 4.22Å; K33-F106 HydrophobicContact CB-CE2 3.91Å; K33-F106 HydrophobicContact CD-CE2 3.75Å; K33-F106 HydrophobicContact CD-CZ 4Å; K33-F106 HydrophobicContact CG-CE2 3.84Å; K33-L167 HydrophobicContact CB-CD1 3.55Å; K33-L167 HydrophobicContact CD-CD1 4.28Å
34I94.1Very high84.6Confident0 Ų030.1 Ų30.10%016%0.161CC..EExtended strand (participates in β ladder)trans-137148.9172.7-162.3156.8000108.5F3 F5 V31 A44 L47 I48 R104 L105 F106F3-I34 HydrophobicContact CB-CD1 4.11Å; F3-I34 HydrophobicContact CB-CG1 3.87Å; F3-I34 CarbonylContact O-C 3.58Å; F3-I34 VanDerWaalsContact O-CA 3.28Å; F3-I34 WeakPolarHBondContact O-CA 3.39Å; F5-I34 HydrophobicContact CD2-CD1 3.9Å; F5-I34 HydrophobicContact CD2-CG1 3.97Å; F5-I34 HydrophobicContact CE2-CD1 3.57Å; F5-I34 HydrophobicContact CE2-CG1 4.08Å; V31-I34 HydrophobicContact CG1-CB 3.86Å; V31-I34 HydrophobicContact CG1-CD1 4.11Å; V31-I34 HydrophobicContact CG1-CG1 4.45Å; I34-A44 HydrophobicContact CB-CB 4.4Å; I34-A44 HydrophobicContact CD1-CB 3.95Å; I34-A44 HydrophobicContact CG1-CB 3.68Å; I34-A44 HydrophobicContact CG2-CB 3.86Å; I34-L47 HydrophobicContact CD1-CB 4.13Å; I34-L47 HydrophobicContact CD1-CD1 3.78Å; I34-I48 HydrophobicContact CB-CG1 4.28Å; I34-I48 HydrophobicContact CG2-CD1 3.94Å; I34-I48 HydrophobicContact CG2-CG1 3.3Å; I34-R104 PolarHBondContact N-O 3.28Å; I34-L105 HydrophobicContact CG2-CB 4.42Å; I34-L105 HydrophobicContact CG2-CD1 3.66Å; I34-L105 WeakPolarHBondContact O-CA 3.18Å; I34-F106 PolarHBondContact O-N 2.92Å
35S95.3Very high85.2Confident0 Ų026.4 Ų26.40%014%0.144CC..EExtended strand (participates in β ladder)trans-135164.1178.958.40000111.6F3 S4 F5 F106 P165F3-S35 PolarHBondContact O-N 2.8Å; F3-S35 PolarHBondContact O-OG 3.41Å; S4-S35 WeakPolarHBondContact CA-O 3.25Å; S4-S35 WeakPolarHBondContact CA-OG 3.25Å; S4-S35 VanDerWaalsContact CB-OG 3.26Å; S4-S35 WeakPolarHBondContact CB-OG 3.15Å; S4-S35 PolarHBondContact OG-OG 2.94Å; F5-S35 PolarHBondContact N-O 2.83Å; S35-F106 CarbonylContact C-O 3.6Å; S35-F106 WeakPolarHBondContact CA-O 3.31Å; S35-P165 WeakPolarHBondContact CB-O 3.28Å; S35-P165 PolarHBondContact OG-O 3.46Å
36G95.9Very high85.9Confident0 Ų026.2 Ų26.20%014%0.144CC..EExtended strand (participates in β ladder)trans174.7173.9170.400000114.5F5 F106 S108F5-G36 WeakPolarHBondContact O-CA 3.19Å; G36-F106 PolarHBondContact N-O 3.1Å; G36-S108 WeakPolarHBondContact O-CB 3.28Å; G36-S108 PolarHBondContact O-N 2.87Å
37A95Very high86.7Confident0 Ų027.4 Ų27.40%015%0.15CC..SBendtrans-120.5151.1172.300000110.2F5 G7 G39 G40 A41F5-A37 PolarHBondContact O-N 2.89Å; G7-A37 WeakPolarHBondContact CA-O 3.26Å; G7-A37 PolarHBondContact N-O 2.92Å; A37-G39 PolarHBondContact O-N 3.23Å; A37-G40 VanDerWaalsContact O-CA 3.29Å; A37-G40 WeakPolarHBondContact O-CA 3.41Å; A37-G40 PolarHBondContact O-N 3.35Å; A37-A41 PolarHBondContact O-N 3.3Å; A37-A41 VanDerWaalsContact O-N 3.14Å
38S94Very high87.6Confident5 Ų524.3 Ų24.34%0.03513%0.129CC..Hα-helixtrans53.7-132.4167.7-162.80000113.1G40 A41 M42 S136 D157S38-G40 PolarHBondContact O-N 3.38Å; S38-G40 VanDerWaalsContact O-N 3.16Å; S38-A41 WeakPolarHBondContact O-CB 3.38Å; S38-A41 PolarHBondContact O-N 2.85Å; S38-M42 PolarHBondContact O-N 3.01Å; S38-S136 WeakPolarHBondContact CA-O 3.3Å; S38-S136 WeakPolarHBondContact CB-O 3.13Å; S38-S136 PolarHBondContact N-O 3.32Å; S38-S136 PolarHBondContact N-OG 3.25Å; S38-D157 WeakPolarHBondContact CB-OD2 3.48Å; S38-D157 PolarHBondContact OG-OD2 2.92Å
39G90.9Very high88.8Confident12 Ų1221.6 Ų21.612%0.12412%0.115CC..Hα-helixtrans-55.9-25.9173.300000114.8A37 M42 A43A37-G39 PolarHBondContact O-N 3.23Å; G39-M42 PolarHBondContact O-N 2.97Å; G39-A43 PolarHBondContact O-N 3.33Å
40G93.3Very high89.7Confident0 Ų023.8 Ų23.80%013%0.127CC..Hα-helixtrans-68.9-41.317200000113.1F5 S6 A37 S38 M42 A43 A44F5-G40 WeakPolarHBondContact CB-O 3.44Å; S6-G40 WeakPolarHBondContact O-CA 3.04Å; S6-G40 PolarHBondContact O-N 2.97Å; A37-G40 VanDerWaalsContact O-CA 3.29Å; A37-G40 WeakPolarHBondContact O-CA 3.41Å; A37-G40 PolarHBondContact O-N 3.35Å; S38-G40 PolarHBondContact O-N 3.38Å; S38-G40 VanDerWaalsContact O-N 3.16Å; G40-M42 PolarHBondContact O-N 2.98Å; G40-A43 PolarHBondContact O-N 2.74Å; G40-A44 WeakPolarHBondContact O-CB 3.36Å; G40-A44 PolarHBondContact O-N 3.14Å
41A95.1Very high91.1Very high0 Ų020.8 Ų20.80%011%0.108CC..Hα-helixtrans-60.4-32.7173.500000112.4A37 S38 C45 I107 L133A37-A41 PolarHBondContact O-N 3.3Å; A37-A41 VanDerWaalsContact O-N 3.14Å; S38-A41 WeakPolarHBondContact O-CB 3.38Å; S38-A41 PolarHBondContact O-N 2.85Å; A41-C45 WeakPolarHBondContact O-CB 3.33Å; A41-C45 PolarHBondContact O-N 3.19Å; A41-I107 HydrophobicContact CB-CG1 4.29Å; A41-I107 HydrophobicContact CB-CG2 4.23Å; A41-L133 HydrophobicContact CB-CD2 4.04Å
42M93.1Very high91.8Very high46 Ų4621 Ų2123%0.22711%0.11CC..Hα-helixtrans-71.4-42.1174.9-62.2178.2-169.700112.6S38 G39 G40 A44 C45 A46 I85 L133 A137S38-M42 PolarHBondContact O-N 3.01Å; G39-M42 PolarHBondContact O-N 2.97Å; G40-M42 PolarHBondContact O-N 2.98Å; M42-A44 VanDerWaalsContact C-N 3.34Å; M42-C45 PolarHBondContact O-N 3Å; M42-A46 WeakPolarHBondContact O-CB 3.46Å; M42-A46 PolarHBondContact O-N 2.88Å; M42-I85 HydrophobicContact CE-CD1 4Å; M42-I85 HydrophobicContact CE-CG1 4.31Å; M42-I85 HydrophobicContact CE-CG2 3.64Å; M42-L133 HydrophobicContact CG-CD2 4.36Å; M42-A137 HydrophobicContact CE-CB 3.48Å; M42-A137 VanDerWaalsContact CE-CB 3.48Å
43A92.8Very high92.2Very high6 Ų616.5 Ų16.55%0.059%0.09CC..Hα-helixtrans-63.9-40.917400000111.7F5 H15 G39 G40 A46 L47F5-A43 HydrophobicContact CD1-CB 4.17Å; H15-A43 HydrophobicContact CB-CB 3.59Å; G39-A43 PolarHBondContact O-N 3.33Å; G40-A43 PolarHBondContact O-N 2.74Å; A43-A46 PolarHBondContact O-N 2.93Å; A43-L47 PolarHBondContact O-N 3.38Å
44A93.8Very high91.9Very high0 Ų012.4 Ų12.40%07%0.073CC..Hα-helixtrans-58.7-47.3173.100000112.3I34 G40 M42 L47 I48 L105I34-A44 HydrophobicContact CB-CB 4.4Å; I34-A44 HydrophobicContact CD1-CB 3.95Å; I34-A44 HydrophobicContact CG1-CB 3.68Å; I34-A44 HydrophobicContact CG2-CB 3.86Å; G40-A44 WeakPolarHBondContact O-CB 3.36Å; G40-A44 PolarHBondContact O-N 3.14Å; M42-A44 VanDerWaalsContact C-N 3.34Å; A44-L47 PolarHBondContact O-N 3.32Å; A44-I48 PolarHBondContact O-N 3.05Å; A44-I48 VanDerWaalsContact O-N 3.14Å; A44-L105 HydrophobicContact CB-CD1 3.67Å
45C93.8Very high91.5Very high2 Ų216.1 Ų16.11%0.0149%0.09CC..Hα-helixtrans-61.6-43.4174.5-170.60000112A41 M42 L47 I48 C49 L105 L133A41-C45 WeakPolarHBondContact O-CB 3.33Å; A41-C45 PolarHBondContact O-N 3.19Å; M42-C45 PolarHBondContact O-N 3Å; C45-L47 VanDerWaalsContact C-N 3.29Å; C45-L47 PolarHBondContact O-N 3.37Å; C45-I48 PolarHBondContact O-N 3.18Å; C45-C49 WeakPolarHBondContact O-CB 3.26Å; C45-C49 PolarHBondContact O-N 3.49Å; C45-L105 HydrophobicContact CB-CD2 3.71Å; C45-L133 HydrophobicContact CB-CD1 4.21Å; C45-L133 HydrophobicContact CB-CD2 4.18Å
46A92.1Very high91.1Very high3 Ų317.4 Ų17.43%0.02510%0.098CC..Hα-helixtrans-61.7-34.3179.300000113.4M42 A43 N50 L51 V56M42-A46 WeakPolarHBondContact O-CB 3.46Å; M42-A46 PolarHBondContact O-N 2.88Å; A43-A46 PolarHBondContact O-N 2.93Å; A46-N50 PolarHBondContact O-N 3.44Å; A46-L51 HydrophobicContact CB-CB 4.36Å; A46-L51 HydrophobicContact CB-CD1 4.01Å; A46-L51 HydrophobicContact CB-CG 4.39Å; A46-L51 PolarHBondContact O-N 2.74Å; A46-V56 HydrophobicContact CB-CG2 4.1Å
47L91Very high90.7Very high28 Ų2817.4 Ų17.415%0.14710%0.098CC..Hα-helixtrans-69.4-52.4172.9-78.1168.1000111.8F5 A19 I34 A43 A44 C45 C49 N50F5-L47 HydrophobicContact CE2-CD1 3.94Å; F5-L47 HydrophobicContact CZ-CD1 3.67Å; A19-L47 HydrophobicContact CB-CD1 4.01Å; A19-L47 HydrophobicContact CB-CD2 3.81Å; A19-L47 HydrophobicContact CB-CG 3.89Å; I34-L47 HydrophobicContact CD1-CB 4.13Å; I34-L47 HydrophobicContact CD1-CD1 3.78Å; A43-L47 PolarHBondContact O-N 3.38Å; A44-L47 PolarHBondContact O-N 3.32Å; C45-L47 VanDerWaalsContact C-N 3.29Å; C45-L47 PolarHBondContact O-N 3.37Å; L47-C49 PolarHBondContact O-N 3.42Å; L47-N50 PolarHBondContact O-N 2.99Å
48I91.5Very high90.4Very high11 Ų1119.8 Ų19.86%0.05612%0.115CC..Hα-helixtrans-64-37.3-178.1-71.9-67.5000113.1V31 I34 A44 C45 N50 M100 R104V31-I48 HydrophobicContact CB-CD1 4.49Å; V31-I48 HydrophobicContact CG1-CD1 3.93Å; I34-I48 HydrophobicContact CB-CG1 4.28Å; I34-I48 HydrophobicContact CG2-CD1 3.94Å; I34-I48 HydrophobicContact CG2-CG1 3.3Å; A44-I48 PolarHBondContact O-N 3.05Å; A44-I48 VanDerWaalsContact O-N 3.14Å; C45-I48 PolarHBondContact O-N 3.18Å; I48-N50 PolarHBondContact O-N 3.44Å; I48-M100 WeakPolarHBondContact CG2-O 3.47Å; I48-R104 HydrophobicContact CD1-CB 4.13Å
49C90.1Very high90Very high7 Ų720.4 Ų20.45%0.04712%0.117CC..THydrogen-bonded Turntrans-833.7175.1-64.20000113.4C45 L47 L51C45-C49 WeakPolarHBondContact O-CB 3.26Å; C45-C49 PolarHBondContact O-N 3.49Å; L47-C49 PolarHBondContact O-N 3.42Å; C49-L51 VanDerWaalsContact C-N 3.26Å; C49-L51 HydrophobicContact CB-CD2 3.74Å; C49-L51 HydrophobicContact CB-CG 3.93Å; C49-L51 PolarHBondContact O-N 3.38Å
50N87.7Confident89.9Confident65 Ų6521.7 Ų21.735%0.34812%0.121SC..THydrogen-bonded Turntrans54.833.9178.2-167.417.6000114.3K23 A46 L47 I48K23-N50 WeakPolarHBondContact CE-OD1 3.26Å; K23-N50 PolarHBondContact NZ-O 3.3Å; K23-N50 PolarHBondContact NZ-OD1 3.4Å; A46-N50 PolarHBondContact O-N 3.44Å; L47-N50 PolarHBondContact O-N 2.99Å; I48-N50 PolarHBondContact O-N 3.44Å
51L88.9Confident89.6Confident26 Ų2621.8 Ų21.814%0.13612%0.122CC..  trans-64.2161.9-170.9-56.4-174.9000113.4K23 A46 C49 L53 V56 L93K23-L51 PolarHBondContact NZ-O 3.24Å; A46-L51 HydrophobicContact CB-CB 4.36Å; A46-L51 HydrophobicContact CB-CD1 4.01Å; A46-L51 HydrophobicContact CB-CG 4.39Å; A46-L51 PolarHBondContact O-N 2.74Å; C49-L51 VanDerWaalsContact C-N 3.26Å; C49-L51 HydrophobicContact CB-CD2 3.74Å; C49-L51 HydrophobicContact CB-CG 3.93Å; C49-L51 PolarHBondContact O-N 3.38Å; L51-L53 PolarHBondContact O-N 3.32Å; L51-L53 VanDerWaalsContact O-N 3.16Å; L51-V56 HydrophobicContact CB-CG2 4.22Å; L51-V56 HydrophobicContact CD1-CG2 4.31Å; L51-L93 HydrophobicContact CD1-CD2 4.1Å
52C87.6Confident89.2Confident29 Ų2925.3 Ų25.320%0.19614%0.135CC..  trans-73.4102.6172.1-170.80000109.7G54 Q55 V56 C716C52-G54 PolarHBondContact O-N 2.77Å; C52-G54 VanDerWaalsContact O-N 3.11Å; C52-Q55 HydrophobicContact CB-CB 4.42Å; C52-Q55 WeakPolarHBondContact O-CB 3.38Å; C52-Q55 PolarHBondContact O-N 3.1Å; C52-V56 PolarHBondContact O-N 2.9Å; C52-C716 HydrophobicContact CB-CB 4.15Å; C52-C716 WeakPolarHBondContact CB-SG 3.19Å; C52-C716 WeakPolarHBondContact SG-CB 3.33Å; C52-C716 CovalentContact SG-SG 2.04Å; C52-C716 PolarHBondContact SG-SG 3.06Å
53L87.8Confident88.9Confident17 Ų1723.8 Ų23.89%0.08913%0.128CC..Hα-helixtrans-60.7-24.2-173-63.7178000114.2A19 A20 K23 L51 C57 V337A19-L53 HydrophobicContact CB-CD1 4.16Å; A19-L53 HydrophobicContact CB-CD2 4.07Å; A20-L53 HydrophobicContact CB-CD1 4.08Å; K23-L53 HydrophobicContact CB-CD1 4.36Å; K23-L53 HydrophobicContact CD-CD1 3.91Å; K23-L53 HydrophobicContact CD-CG 4.33Å; L51-L53 PolarHBondContact O-N 3.32Å; L51-L53 VanDerWaalsContact O-N 3.16Å; L53-C57 VanDerWaalsContact O-CB 3.25Å; L53-C57 WeakPolarHBondContact O-CB 3.29Å; L53-C57 PolarHBondContact O-N 3.07Å; L53-V337 HydrophobicContact CB-CG2 4.12Å
54G86Confident88.6Confident4 Ų423.5 Ų23.54%0.04113%0.126CC..Hα-helixtrans-67.2-34.5171.400000113.3C52 C57 S58 S340C52-G54 PolarHBondContact O-N 2.77Å; C52-G54 VanDerWaalsContact O-N 3.11Å; G54-C57 WeakPolarHBondContact O-CB 3.49Å; G54-C57 PolarHBondContact O-N 2.82Å; G54-S58 WeakPolarHBondContact O-CB 3.45Å; G54-S58 PolarHBondContact O-N 3.26Å; G54-S340 PolarHBondContact O-OG 2.83Å
55Q85.2Confident88.1Confident77 Ų7724 Ų2436%0.3613%0.128SC..Hα-helixtrans-69.1-47.5174.6-168.76047.100110.4C52 C57 S58 D59 F92C52-Q55 HydrophobicContact CB-CB 4.42Å; C52-Q55 WeakPolarHBondContact O-CB 3.38Å; C52-Q55 PolarHBondContact O-N 3.1Å; Q55-C57 PolarHBondContact O-N 3.22Å; Q55-S58 WeakPolarHBondContact O-CA 3.36Å; Q55-S58 WeakPolarHBondContact O-CB 3.22Å; Q55-S58 PolarHBondContact O-N 3.48Å; Q55-D59 PolarHBondContact NE2-OD2 3.28Å; Q55-D59 PolarHBondContact O-N 3.49Å; Q55-F92 HydrophobicContact CG-CD1 3.48Å; Q55-F92 VanDerWaalsContact CG-CD1 3.48Å; Q55-F92 HydrophobicContact CG-CE1 3.41Å; Q55-F92 VanDerWaalsContact CG-CE1 3.41Å; Q55-F92 HydrophobicContact CG-CG 4.09Å; Q55-F92 HydrophobicContact CG-CZ 3.97Å
56V87.2Confident87.7Confident28 Ų2826.2 Ų26.217%0.1714%0.14CC..Hα-helixtrans-55.4-42.1174.6-177.20000111.2V16 A46 L51 C52 I60V16-V56 HydrophobicContact CG2-CG1 4.1Å; A46-V56 HydrophobicContact CB-CG2 4.1Å; L51-V56 HydrophobicContact CB-CG2 4.22Å; L51-V56 HydrophobicContact CD1-CG2 4.31Å; C52-V56 PolarHBondContact O-N 2.9Å; V56-I60 HydrophobicContact CG1-CD1 4.1Å; V56-I60 WeakPolarHBondContact O-CG1 3.2Å; V56-I60 PolarHBondContact O-N 3.03Å; V56-I60 VanDerWaalsContact O-N 3.08Å
57C88.7Confident87.2Confident0 Ų026 Ų260%014%0.139CC..Hα-helixtrans-60.8-50.5172.4-170.80000112.2V16 L53 G54 Q55 D59 I60 L61 V337V16-C57 HydrophobicContact CG1-CB 4.13Å; L53-C57 VanDerWaalsContact O-CB 3.25Å; L53-C57 WeakPolarHBondContact O-CB 3.29Å; L53-C57 PolarHBondContact O-N 3.07Å; G54-C57 WeakPolarHBondContact O-CB 3.49Å; G54-C57 PolarHBondContact O-N 2.82Å; Q55-C57 PolarHBondContact O-N 3.22Å; C57-D59 VanDerWaalsContact C-N 3.26Å; C57-D59 PolarHBondContact O-N 3.47Å; C57-I60 PolarHBondContact O-N 3.07Å; C57-L61 WeakPolarHBondContact O-CB 3.4Å; C57-L61 VanDerWaalsContact O-CD1 3.28Å; C57-L61 WeakPolarHBondContact O-CD1 3.48Å; C57-L61 WeakPolarHBondContact O-CG 3.32Å; C57-L61 PolarHBondContact O-N 3.43Å; C57-V337 HydrophobicContact CB-CG1 4.28Å
58S87.6Confident86.8Confident49 Ų4928.3 Ų28.334%0.34315%0.145SC..Hα-helixtrans-56.7-39.8179.2-165.30000112G54 Q55 L61 R62G54-S58 WeakPolarHBondContact O-CB 3.45Å; G54-S58 PolarHBondContact O-N 3.26Å; Q55-S58 WeakPolarHBondContact O-CA 3.36Å; Q55-S58 WeakPolarHBondContact O-CB 3.22Å; Q55-S58 PolarHBondContact O-N 3.48Å; S58-L61 CarbonylContact O-C 3.25Å; S58-L61 PolarHBondContact O-N 2.93Å; S58-R62 WeakPolarHBondContact O-CB 3.23Å; S58-R62 PolarHBondContact O-N 3.04Å
59D86.7Confident86.1Confident18 Ų1831.3 Ų31.310%0.09616%0.159CC..Hα-helixtrans-75.4-41.6179.7-82.7-83.4000113.7Q55 C57 L61 R62 V63 F92Q55-D59 PolarHBondContact NE2-OD2 3.28Å; Q55-D59 PolarHBondContact O-N 3.49Å; C57-D59 VanDerWaalsContact C-N 3.26Å; C57-D59 PolarHBondContact O-N 3.47Å; D59-L61 PolarHBondContact O-N 2.96Å; D59-R62 WeakPolarHBondContact O-CB 3.25Å; D59-R62 PolarHBondContact O-N 3.33Å; D59-R62 VanDerWaalsContact O-N 3.07Å; D59-R62 IonicContact OD1-CZ 3.46Å; D59-R62 IonicContact OD1-NE 2.97Å; D59-R62 PolarHBondContact OD1-NE 3.26Å; D59-R62 IonicContact OD1-NH2 2.71Å; D59-R62 PolarHBondContact OD1-NH2 3.17Å; D59-V63 VanDerWaalsContact O-CG2 3.28Å; D59-V63 WeakPolarHBondContact O-CG2 3.45Å; D59-V63 PolarHBondContact O-N 3.4Å; D59-F92 HydrophobicContact CB-CE2 4.25Å; D59-F92 WeakPolarHBondContact OD1-CE2 3.43Å; D59-F92 WeakPolarHBondContact OD2-CE2 3.09Å; D59-F92 WeakPolarHBondContact OD2-CZ 3.18Å
60I87.2Confident85.2Confident40 Ų4035.9 Ų35.921%0.20518%0.175CC..Hα-helixtrans-56.6-40.8170.9-70.4165.4000110.1I13 V16 V56 C57 S64 M225I13-I60 HydrophobicContact CB-CG2 4.2Å; I13-I60 HydrophobicContact CD1-CG2 4.16Å; V16-I60 HydrophobicContact CG2-CD1 3.61Å; V56-I60 HydrophobicContact CG1-CD1 4.1Å; V56-I60 WeakPolarHBondContact O-CG1 3.2Å; V56-I60 PolarHBondContact O-N 3.03Å; V56-I60 VanDerWaalsContact O-N 3.08Å; C57-I60 PolarHBondContact O-N 3.07Å; I60-S64 WeakPolarHBondContact O-CB 3.27Å; I60-S64 PolarHBondContact O-N 3.38Å; I60-S64 PolarHBondContact O-OG 3.16Å; I60-M225 HydrophobicContact CG2-CE 3.97Å
61L87.5Confident83.9Confident2 Ų237.4 Ų37.41%0.0120%0.197CC..Hα-helixtrans-69.6-38.1175.3-64.7161.5000112.3I13 C57 S58 D59 S64 I65 P222 M225 S340 L341 A344I13-L61 HydrophobicContact CD1-CG 4.49Å; C57-L61 WeakPolarHBondContact O-CB 3.4Å; C57-L61 VanDerWaalsContact O-CD1 3.28Å; C57-L61 WeakPolarHBondContact O-CD1 3.48Å; C57-L61 WeakPolarHBondContact O-CG 3.32Å; C57-L61 PolarHBondContact O-N 3.43Å; S58-L61 CarbonylContact O-C 3.25Å; S58-L61 PolarHBondContact O-N 2.93Å; D59-L61 PolarHBondContact O-N 2.96Å; L61-S64 WeakPolarHBondContact O-CB 3.35Å; L61-S64 PolarHBondContact O-N 3.44Å; L61-I65 WeakPolarHBondContact O-CB 3.47Å; L61-I65 VanDerWaalsContact O-CG1 3.29Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.38Å; L61-P222 HydrophobicContact CD2-CB 4.26Å; L61-M225 HydrophobicContact CD2-CB 4.15Å; L61-M225 HydrophobicContact CD2-CE 4.38Å; L61-M225 HydrophobicContact CD2-SD 3.96Å; L61-S340 WeakPolarHBondContact CD1-O 3.26Å; L61-L341 HydrophobicContact CD1-CD2 3.81Å; L61-L341 HydrophobicContact CD1-CG 4.26Å; L61-L341 HydrophobicContact CD2-CD2 4.08Å; L61-L341 HydrophobicContact CG-CD2 4.49Å; L61-A344 HydrophobicContact CB-CB 3.77Å; L61-A344 HydrophobicContact CD1-CB 3.71Å; L61-A344 HydrophobicContact CD2-CB 4.17Å; L61-A344 HydrophobicContact CG-CB 4.09Å
62R87.2Confident82.6Confident73 Ų7339.6 Ų39.628%0.27521%0.209SC..Hα-helixtrans-59.1-49.9173.6179.5176.368.5102.4-4.8110.9S58 D59 S64 I65 L66 E87S58-R62 WeakPolarHBondContact O-CB 3.23Å; S58-R62 PolarHBondContact O-N 3.04Å; D59-R62 WeakPolarHBondContact O-CB 3.25Å; D59-R62 PolarHBondContact O-N 3.33Å; D59-R62 VanDerWaalsContact O-N 3.07Å; D59-R62 IonicContact OD1-CZ 3.46Å; D59-R62 IonicContact OD1-NE 2.97Å; D59-R62 PolarHBondContact OD1-NE 3.26Å; D59-R62 IonicContact OD1-NH2 2.71Å; D59-R62 PolarHBondContact OD1-NH2 3.17Å; R62-S64 VanDerWaalsContact C-N 3.31Å; R62-S64 PolarHBondContact O-N 3.11Å; R62-I65 PolarHBondContact O-N 3.28Å; R62-L66 HydrophobicContact CG-CD1 4Å; R62-L66 WeakPolarHBondContact O-CB 3.44Å; R62-L66 VanDerWaalsContact O-CG 3.23Å; R62-L66 WeakPolarHBondContact O-CG 3.42Å; R62-L66 PolarHBondContact O-N 2.84Å; R62-E87 IonicContact CZ-OE2 3.27Å; R62-E87 IonicContact NH1-OE2 2.93Å; R62-E87 PolarHBondContact NH1-OE2 3.07Å; R62-E87 IonicContact NH2-OE2 2.67Å; R62-E87 PolarHBondContact NH2-OE2 3.46Å
63V86.2Confident81.7Confident14 Ų1439 Ų399%0.08521%0.207CC..Hα-helixtrans-61.5-41.9176.7-175.60000110.7F10 D59 L66 A67 F79 L81 I84F10-V63 HydrophobicContact CE1-CB 4.25Å; F10-V63 HydrophobicContact CE1-CG1 3.78Å; F10-V63 HydrophobicContact CZ-CG1 3.94Å; D59-V63 VanDerWaalsContact O-CG2 3.28Å; D59-V63 WeakPolarHBondContact O-CG2 3.45Å; D59-V63 PolarHBondContact O-N 3.4Å; V63-L66 PolarHBondContact O-N 3.12Å; V63-A67 PolarHBondContact O-N 3.45Å; V63-F79 HydrophobicContact CG1-CE2 4.41Å; V63-F79 HydrophobicContact CG1-CZ 3.85Å; V63-L81 HydrophobicContact CG1-CD1 3.44Å; V63-L81 VanDerWaalsContact CG1-CD1 3.44Å; V63-I84 HydrophobicContact CG2-CG2 3.64Å
64S86.3Confident80.7Confident1 Ų138.3 Ų38.31%0.00720%0.203CC..Hα-helixtrans-62.2-47.6178.4-59.40000112.3F10 I60 L61 R62 A67 R68 M225F10-S64 VanDerWaalsContact CD1-OG 3.24Å; F10-S64 WeakPolarHBondContact CD1-OG 3.34Å; F10-S64 WeakPolarHBondContact CE1-OG 3.18Å; I60-S64 WeakPolarHBondContact O-CB 3.27Å; I60-S64 PolarHBondContact O-N 3.38Å; I60-S64 PolarHBondContact O-OG 3.16Å; L61-S64 WeakPolarHBondContact O-CB 3.35Å; L61-S64 PolarHBondContact O-N 3.44Å; R62-S64 VanDerWaalsContact C-N 3.31Å; R62-S64 PolarHBondContact O-N 3.11Å; S64-A67 PolarHBondContact O-N 2.82Å; S64-R68 WeakPolarHBondContact O-CB 3.49Å; S64-R68 WeakPolarHBondContact O-CG 3.46Å; S64-R68 PolarHBondContact O-N 2.94Å; S64-M225 WeakPolarHBondContact OG-CE 3.41Å
65I84.6Confident79.8Confident9 Ų942.5 Ų42.55%0.04622%0.224CC..Hα-helixtrans-62.9-44.1176.1-68.8166.4000110.5L61 R62 A67 R68 Q69 P222 A344 M351L61-I65 WeakPolarHBondContact O-CB 3.47Å; L61-I65 VanDerWaalsContact O-CG1 3.29Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.38Å; R62-I65 PolarHBondContact O-N 3.28Å; I65-A67 VanDerWaalsContact C-N 3.29Å; I65-A67 PolarHBondContact O-N 3.01Å; I65-R68 PolarHBondContact O-N 2.72Å; I65-Q69 VanDerWaalsContact O-CG 3.29Å; I65-Q69 WeakPolarHBondContact O-CG 3.37Å; I65-Q69 PolarHBondContact O-N 2.82Å; I65-P222 HydrophobicContact CG1-CG 4.38Å; I65-A344 HydrophobicContact CD1-CB 4.09Å; I65-M351 HydrophobicContact CG2-CE 3.86Å; I65-M351 HydrophobicContact CG2-SD 4.47Å
66L83.9Confident78.8Confident49 Ų4940.1 Ų40.126%0.25721%0.213SC..Hα-helixtrans-62.1-33.9177.9-74.5170.8000113.1R62 V63 F79 I84R62-L66 HydrophobicContact CG-CD1 4Å; R62-L66 WeakPolarHBondContact O-CB 3.44Å; R62-L66 VanDerWaalsContact O-CG 3.23Å; R62-L66 WeakPolarHBondContact O-CG 3.42Å; R62-L66 PolarHBondContact O-N 2.84Å; V63-L66 PolarHBondContact O-N 3.12Å; L66-F79 HydrophobicContact CB-CE2 4.12Å; L66-I84 HydrophobicContact CD1-CD1 4.34Å; L66-I84 HydrophobicContact CD1-CG2 4.34Å
67A81.6Confident77.6Confident0 Ų041.4 Ų41.40%022%0.222CC..Hα-helixtrans-69.8-48.6171.700000111.3F10 V63 S64 I65 Q69 R70 G73 P74 F79 P219F10-A67 HydrophobicContact CZ-CB 4.1Å; V63-A67 PolarHBondContact O-N 3.45Å; S64-A67 PolarHBondContact O-N 2.82Å; I65-A67 VanDerWaalsContact C-N 3.29Å; I65-A67 PolarHBondContact O-N 3.01Å; A67-Q69 PolarHBondContact O-N 2.86Å; A67-R70 PolarHBondContact O-N 3.44Å; A67-R70 VanDerWaalsContact O-N 3.15Å; A67-G73 CarbonylContact O-C 3.52Å; A67-G73 WeakPolarHBondContact O-CA 3.35Å; A67-P74 HydrophobicContact CB-CG 4.03Å; A67-F79 HydrophobicContact CB-CD2 4.39Å; A67-F79 HydrophobicContact CB-CE1 4.34Å; A67-F79 HydrophobicContact CB-CE2 3.79Å; A67-F79 HydrophobicContact CB-CZ 3.75Å; A67-P219 HydrophobicContact CB-CG 3.84Å
68R82.6Confident76.6Confident75 Ų7544.2 Ų44.228%0.28324%0.242SC..Hα-helixtrans-64.1-23.8-178.6-68.6168.86466.17.5113.8S64 I65 R70 P219 P220 E348S64-R68 WeakPolarHBondContact O-CB 3.49Å; S64-R68 WeakPolarHBondContact O-CG 3.46Å; S64-R68 PolarHBondContact O-N 2.94Å; I65-R68 PolarHBondContact O-N 2.72Å; R68-R70 PolarHBondContact O-N 3.18Å; R68-P219 WeakPolarHBondContact CD-O 3.29Å; R68-P219 HydrophobicContact CG-CB 4.43Å; R68-P219 HydrophobicContact CG-CG 4.1Å; R68-P219 PolarHBondContact NH1-O 3.37Å; R68-P220 WeakPolarHBondContact CD-O 3.4Å; R68-P220 PolarHBondContact NE-O 3.28Å; R68-P220 VanDerWaalsContact NH1-C 3.34Å; R68-E348 IonicContact CZ-OE1 3.29Å; R68-E348 IonicContact NE-OE1 2.89Å; R68-E348 PolarHBondContact NE-OE1 3.19Å; R68-E348 IonicContact NE-OE2 2.76Å; R68-E348 PolarHBondContact NE-OE2 3.34Å; R68-E348 VanDerWaalsContact NE-OE2 3.09Å; R68-E348 IonicContact NH2-OE1 2.64Å; R68-E348 PolarHBondContact NH2-OE1 3.3Å
69Q77.6Confident75.9Confident74 Ų7442.8 Ų42.835%0.34623%0.229SC..THydrogen-bonded Turntrans-64.4-13.4173.3-80.1171.87.100114.8I65 A67 M351I65-Q69 VanDerWaalsContact O-CG 3.29Å; I65-Q69 WeakPolarHBondContact O-CG 3.37Å; I65-Q69 PolarHBondContact O-N 2.82Å; A67-Q69 PolarHBondContact O-N 2.86Å; Q69-M351 HydrophobicContact CG-CE 3.62Å; Q69-M351 HydrophobicContact CG-SD 3.81Å; Q69-M351 PolarHBondContact NE2-SD 3.36Å
70R72.1Confident75.5Confident104 Ų10445.4 Ų45.439%0.39224%0.243SC..SBendtrans-109.7142.1-172.1-52.8-59.3171.6166.7-4.9111.4A67 R68 L72 G73 H76A67-R70 PolarHBondContact O-N 3.44Å; A67-R70 VanDerWaalsContact O-N 3.15Å; R68-R70 PolarHBondContact O-N 3.18Å; R70-L72 PolarHBondContact O-N 2.92Å; R70-G73 WeakPolarHBondContact O-CA 3.44Å; R70-G73 PolarHBondContact O-N 2.93Å; R70-H76 HydrophobicContact CB-CB 3.62Å; R70-H76 HydrophobicContact CG-CB 4.05Å
71A59.4Low75.3Confident97 Ų9744.3 Ų44.380%0.80224%0.238SC*.THydrogen-bonded Turntrans-62.2-26.3-17600000114.2
72L61.3Low75.1Confident72 Ų7245.5 Ų45.538%0.37725%0.245SC..THydrogen-bonded Turntrans-100.712.3173.9-60176.5000112.6R70 L75 H76R70-L72 PolarHBondContact O-N 2.92Å; L72-L75 HydrophobicContact CB-CB 4.34Å; L72-L75 WeakPolarHBondContact O-CB 3.41Å; L72-L75 PolarHBondContact O-N 3.3Å; L72-L75 VanDerWaalsContact O-N 3.09Å; L72-H76 HydrophobicContact CB-CB 4.25Å
73G68.5Low75Confident15 Ų1544.8 Ų44.816%0.15525%0.252CS..G310 helixtrans57.1-136.4-174.800000112.2A67 R70 L75 H76A67-G73 CarbonylContact O-C 3.52Å; A67-G73 WeakPolarHBondContact O-CA 3.35Å; R70-G73 WeakPolarHBondContact O-CA 3.44Å; R70-G73 PolarHBondContact O-N 2.93Å; G73-L75 PolarHBondContact O-N 2.98Å; G73-H76 WeakPolarHBondContact O-CB 3.22Å; G73-H76 PolarHBondContact O-N 3.35Å
74P67.7Low75Confident3 Ų345.4 Ų45.42%0.01925%0.254CS..G310 helixtrans-55.8-27.3173.3-23.332.6000114.7F10 A67 H76 F79 Y142F10-P74 HydrophobicContact CE2-CG 3.99Å; A67-P74 HydrophobicContact CB-CG 4.03Å; P74-H76 PolarHBondContact O-N 3.18Å; P74-F79 HydrophobicContact CB-CD1 4.22Å; P74-F79 HydrophobicContact CB-CE1 4.09Å; P74-F79 VanDerWaalsContact O-CD1 3.3Å; P74-F79 WeakPolarHBondContact O-CD1 3.37Å; P74-Y142 HydrophobicContact CB-CD2 4.31Å; P74-Y142 HydrophobicContact CB-CE1 4.34Å; P74-Y142 HydrophobicContact CB-CE2 3.6Å; P74-Y142 HydrophobicContact CG-CE2 4.01Å
75L66.6Low75Confident92 Ų9246.5 Ų46.548%0.48226%0.259SS..G310 helixtrans-77.73.7-175.4-56.1175.7000113.6L72 G73 Y142 F218L72-L75 HydrophobicContact CB-CB 4.34Å; L72-L75 WeakPolarHBondContact O-CB 3.41Å; L72-L75 PolarHBondContact O-N 3.3Å; L72-L75 VanDerWaalsContact O-N 3.09Å; G73-L75 PolarHBondContact O-N 2.98Å; L75-Y142 HydrophobicContact CD2-CD2 3.8Å; L75-F218 HydrophobicContact CD1-CE1 4.32Å; L75-F218 HydrophobicContact CD1-CZ 4.26Å
76H64.5Low75.3Confident28 Ų2849.5 Ų49.513%0.1327%0.27CS..SBendtrans-73.8130.2-177.7-173-103.1000112.1R70 L72 G73 P74 S78 F79R70-H76 HydrophobicContact CB-CB 3.62Å; R70-H76 HydrophobicContact CG-CB 4.05Å; L72-H76 HydrophobicContact CB-CB 4.25Å; G73-H76 WeakPolarHBondContact O-CB 3.22Å; G73-H76 PolarHBondContact O-N 3.35Å; P74-H76 PolarHBondContact O-N 3.18Å; H76-S78 PolarHBondContact CE1-OG 2.76Å; H76-S78 VanDerWaalsContact CE1-OG 3.25Å; H76-S78 PolarHBondContact ND1-N 2.95Å; H76-S78 PolarHBondContact ND1-OG 3.2Å; H76-S78 PolarHBondContact O-N 3.48Å; H76-F79 HydrophobicContact CB-CB 4.47Å; H76-F79 WeakPolarHBondContact O-CB 3.45Å; H76-F79 PolarHBondContact O-N 3.4Å
77P62.7Low75.6Confident55 Ų5552.2 Ų52.236%0.35728%0.282SS..THydrogen-bonded Turntrans-63.98.4-177.4-25.735.8000117.9T381 K384P77-T381 HydrophobicContact CG-CG2 4.09Å; P77-K384 PolarHBondContact O-NZ 2.7Å
78S67Low75.8Confident58 Ų5852.5 Ų52.541%0.40629%0.285SS..THydrogen-bonded Turntrans-113.9-5.7168.186.70000113.6H76H76-S78 PolarHBondContact CE1-OG 2.76Å; H76-S78 VanDerWaalsContact CE1-OG 3.25Å; H76-S78 PolarHBondContact ND1-N 2.95Å; H76-S78 PolarHBondContact ND1-OG 3.2Å; H76-S78 PolarHBondContact O-N 3.48Å
79F73.2Confident76.2Confident19 Ų1950.2 Ų50.28%0.08328%0.278CS..  trans-90.6119.1172.7-173.2-101.4000107.3F10 V63 L66 A67 P74 H76 L81 I84F10-F79 HydrophobicContact CZ-CZ 4.37Å; V63-F79 HydrophobicContact CG1-CE2 4.41Å; V63-F79 HydrophobicContact CG1-CZ 3.85Å; L66-F79 HydrophobicContact CB-CE2 4.12Å; A67-F79 HydrophobicContact CB-CD2 4.39Å; A67-F79 HydrophobicContact CB-CE1 4.34Å; A67-F79 HydrophobicContact CB-CE2 3.79Å; A67-F79 HydrophobicContact CB-CZ 3.75Å; P74-F79 HydrophobicContact CB-CD1 4.22Å; P74-F79 HydrophobicContact CB-CE1 4.09Å; P74-F79 VanDerWaalsContact O-CD1 3.3Å; P74-F79 WeakPolarHBondContact O-CD1 3.37Å; H76-F79 HydrophobicContact CB-CB 4.47Å; H76-F79 WeakPolarHBondContact O-CB 3.45Å; H76-F79 PolarHBondContact O-N 3.4Å; F79-L81 HydrophobicContact CD1-CB 4.37Å; F79-L81 HydrophobicContact CE1-CB 3.75Å; F79-L81 HydrophobicContact CE1-CD1 4.11Å; F79-L81 HydrophobicContact CE1-CG 4.34Å; F79-L81 HydrophobicContact CZ-CB 4.41Å; F79-L81 HydrophobicContact CZ-CD1 4.05Å; F79-I84 HydrophobicContact CD2-CD1 3.94Å; F79-I84 HydrophobicContact CE2-CD1 3.67Å; F79-I84 HydrophobicContact CZ-CD1 4.29Å
80N77.3Confident76.9Confident73 Ų7349.6 Ų49.639%0.3928%0.279SS..  trans-12392.2175.4177.8-5.9000106.9T82 S83 I84 S143N80-T82 PolarHBondContact O-N 2.86Å; N80-T82 VanDerWaalsContact OD1-CB 3.25Å; N80-T82 WeakPolarHBondContact OD1-CB 3.41Å; N80-T82 PolarHBondContact OD1-N 3.44Å; N80-S83 VanDerWaalsContact CB-OG 3.28Å; N80-S83 WeakPolarHBondContact CB-OG 3.43Å; N80-S83 PolarHBondContact ND2-OG 3.16Å; N80-S83 PolarHBondContact O-N 3.06Å; N80-S83 PolarHBondContact O-OG 3.1Å; N80-S83 PolarHBondContact OD1-N 3.37Å; N80-S83 VanDerWaalsContact OD1-N 3.09Å; N80-I84 WeakPolarHBondContact O-CG1 3.13Å; N80-I84 PolarHBondContact O-N 2.99Å; N80-I84 VanDerWaalsContact O-N 3.15Å; N80-S143 PolarHBondContact OD1-O 2.74Å
81L83Confident77.7Confident17 Ų1749.4 Ų49.49%0.08929%0.29CS..Hα-helixtrans-55.5-43-179-174.949.6000110.6V63 F79 S83 I84 I85 Y142V63-L81 HydrophobicContact CG1-CD1 3.44Å; V63-L81 VanDerWaalsContact CG1-CD1 3.44Å; F79-L81 HydrophobicContact CD1-CB 4.37Å; F79-L81 HydrophobicContact CE1-CB 3.75Å; F79-L81 HydrophobicContact CE1-CD1 4.11Å; F79-L81 HydrophobicContact CE1-CG 4.34Å; F79-L81 HydrophobicContact CZ-CB 4.41Å; F79-L81 HydrophobicContact CZ-CD1 4.05Å; L81-S83 PolarHBondContact O-N 2.84Å; L81-I84 PolarHBondContact O-N 2.86Å; L81-I85 HydrophobicContact CD1-CD1 3.71Å; L81-I85 HydrophobicContact CD1-CG1 4.09Å; L81-I85 HydrophobicContact CG-CD1 3.63Å; L81-I85 HydrophobicContact CG-CG1 4.46Å; L81-I85 WeakPolarHBondContact O-CB 3.5Å; L81-I85 WeakPolarHBondContact O-CD1 3.27Å; L81-I85 VanDerWaalsContact O-CG1 3.28Å; L81-I85 WeakPolarHBondContact O-CG1 3.49Å; L81-I85 PolarHBondContact O-N 3.44Å; L81-Y142 HydrophobicContact CD2-CD1 4.05Å; L81-Y142 HydrophobicContact CD2-CE1 3.61Å
82T84.4Confident78.9Confident27 Ų2748 Ų4817%0.16627%0.265CS..Hα-helixtrans-54.4-47.1177.9-44.90000112.1N80 R86 T134 S143N80-T82 PolarHBondContact O-N 2.86Å; N80-T82 VanDerWaalsContact OD1-CB 3.25Å; N80-T82 WeakPolarHBondContact OD1-CB 3.41Å; N80-T82 PolarHBondContact OD1-N 3.44Å; T82-R86 WeakPolarHBondContact O-CB 3.46Å; T82-R86 PolarHBondContact O-N 2.81Å; T82-T134 HydrophobicContact CG2-CG2 3.35Å; T82-S143 PolarHBondContact OG1-O 3.02Å
83S85Confident80.3Confident59 Ų5944.8 Ų44.841%0.41325%0.249SC..Hα-helixtrans-74.4-35.1179.858.40000113.7N80 L81 I85 R86 E87N80-S83 VanDerWaalsContact CB-OG 3.28Å; N80-S83 WeakPolarHBondContact CB-OG 3.43Å; N80-S83 PolarHBondContact ND2-OG 3.16Å; N80-S83 PolarHBondContact O-N 3.06Å; N80-S83 PolarHBondContact O-OG 3.1Å; N80-S83 PolarHBondContact OD1-N 3.37Å; N80-S83 VanDerWaalsContact OD1-N 3.09Å; L81-S83 PolarHBondContact O-N 2.84Å; S83-I85 VanDerWaalsContact C-N 3.35Å; S83-R86 PolarHBondContact O-N 3.38Å; S83-E87 VanDerWaalsContact O-CB 3.3Å; S83-E87 WeakPolarHBondContact O-CB 3.25Å; S83-E87 PolarHBondContact O-N 2.97Å
84I85.2Confident81.4Confident26 Ų2646.3 Ų46.313%0.13326%0.256CS..Hα-helixtrans-69.3-37.3178.5-59.3162.8000110.2V63 L66 F79 N80 L81 G88V63-I84 HydrophobicContact CG2-CG2 3.64Å; L66-I84 HydrophobicContact CD1-CD1 4.34Å; L66-I84 HydrophobicContact CD1-CG2 4.34Å; F79-I84 HydrophobicContact CD2-CD1 3.94Å; F79-I84 HydrophobicContact CE2-CD1 3.67Å; F79-I84 HydrophobicContact CZ-CD1 4.29Å; N80-I84 WeakPolarHBondContact O-CG1 3.13Å; N80-I84 PolarHBondContact O-N 2.99Å; N80-I84 VanDerWaalsContact O-N 3.15Å; L81-I84 PolarHBondContact O-N 2.86Å; I84-G88 PolarHBondContact O-N 3.03Å; I84-G88 VanDerWaalsContact O-N 3.15Å
85I87.8Confident82.6Confident24 Ų2451.9 Ų51.912%0.12329%0.286CS..Hα-helixtrans-62.9-52170.4-71.8163000110.4M42 L81 S83 E87 G88 L89 A137M42-I85 HydrophobicContact CE-CD1 4Å; M42-I85 HydrophobicContact CE-CG1 4.31Å; M42-I85 HydrophobicContact CE-CG2 3.64Å; L81-I85 HydrophobicContact CD1-CD1 3.71Å; L81-I85 HydrophobicContact CD1-CG1 4.09Å; L81-I85 HydrophobicContact CG-CD1 3.63Å; L81-I85 HydrophobicContact CG-CG1 4.46Å; L81-I85 WeakPolarHBondContact O-CB 3.5Å; L81-I85 WeakPolarHBondContact O-CD1 3.27Å; L81-I85 VanDerWaalsContact O-CG1 3.28Å; L81-I85 WeakPolarHBondContact O-CG1 3.49Å; L81-I85 PolarHBondContact O-N 3.44Å; S83-I85 VanDerWaalsContact C-N 3.35Å; I85-E87 VanDerWaalsContact C-N 3.33Å; I85-E87 PolarHBondContact O-N 3.45Å; I85-G88 PolarHBondContact O-N 3.17Å; I85-L89 HydrophobicContact CG2-CD1 3.65Å; I85-L89 HydrophobicContact CG2-CG 4.14Å; I85-L89 WeakPolarHBondContact O-CG 3.37Å; I85-L89 PolarHBondContact O-N 2.86Å; I85-A137 HydrophobicContact CD1-CB 4.32Å
86R90.6Very high83.8Confident73 Ų7351.5 Ų51.528%0.27528%0.284SS..Hα-helixtrans-61.6-41.1-177.3-150.7-174.2-166.8-81.33.5111.9T82 S83 L89 V90 D127 I130 D131T82-R86 WeakPolarHBondContact O-CB 3.46Å; T82-R86 PolarHBondContact O-N 2.81Å; S83-R86 PolarHBondContact O-N 3.38Å; R86-L89 PolarHBondContact O-N 2.87Å; R86-V90 WeakPolarHBondContact O-CB 3.5Å; R86-V90 VanDerWaalsContact O-CG2 3.26Å; R86-V90 WeakPolarHBondContact O-CG2 3.39Å; R86-V90 PolarHBondContact O-N 3.34Å; R86-D127 IonicContact CZ-OD1 2.83Å; R86-D127 IonicContact NH1-OD1 2.76Å; R86-D127 PolarHBondContact NH1-OD1 3.28Å; R86-D127 IonicContact NH2-OD1 2.93Å; R86-D127 PolarHBondContact NH2-OD1 2.95Å; R86-I130 HydrophobicContact CG-CG2 3.41Å; R86-I130 VanDerWaalsContact CG-CG2 3.41Å; R86-D131 IonicContact CZ-OD1 2.83Å; R86-D131 IonicContact NE-OD1 3.22Å; R86-D131 PolarHBondContact NE-OD1 2.86Å; R86-D131 IonicContact NH2-OD1 3.36Å; R86-D131 PolarHBondContact NH2-OD1 3.01Å; R86-D131 IonicContact NH2-OD2 2.82Å; R86-D131 PolarHBondContact NH2-OD2 3.46Å
87E88.9Confident85.2Confident105 Ų10550.1 Ų50.149%0.49128%0.278SS..Hα-helixtrans-53.4-56.8171.6177.5-167.6-123.800111R62 S83 I85 L89 V90 T91R62-E87 IonicContact CZ-OE2 3.27Å; R62-E87 IonicContact NH1-OE2 2.93Å; R62-E87 PolarHBondContact NH1-OE2 3.07Å; R62-E87 IonicContact NH2-OE2 2.67Å; R62-E87 PolarHBondContact NH2-OE2 3.46Å; S83-E87 VanDerWaalsContact O-CB 3.3Å; S83-E87 WeakPolarHBondContact O-CB 3.25Å; S83-E87 PolarHBondContact O-N 2.97Å; I85-E87 VanDerWaalsContact C-N 3.33Å; I85-E87 PolarHBondContact O-N 3.45Å; E87-L89 PolarHBondContact O-N 2.62Å; E87-V90 PolarHBondContact O-N 3.43Å; E87-T91 PolarHBondContact O-N 3.05Å; E87-T91 VanDerWaalsContact O-N 3.14Å; E87-T91 PolarHBondContact O-OG1 3.37Å
88G86.8Confident86.7Confident7 Ų748.8 Ų48.87%0.07227%0.267CS..Hα-helixtrans-59.7-46.5179.700000113I84 I85 V90 T91 F92I84-G88 PolarHBondContact O-N 3.03Å; I84-G88 VanDerWaalsContact O-N 3.15Å; I85-G88 PolarHBondContact O-N 3.17Å; G88-V90 VanDerWaalsContact C-N 3.32Å; G88-V90 PolarHBondContact O-N 2.89Å; G88-T91 PolarHBondContact O-N 3.23Å; G88-T91 VanDerWaalsContact O-N 3.12Å; G88-F92 WeakPolarHBondContact O-CD2 3.47Å; G88-F92 WeakPolarHBondContact O-CE2 3.45Å; G88-F92 WeakPolarHBondContact O-CG 3.46Å; G88-F92 PolarHBondContact O-N 3.05Å
89L91Very high88Confident26 Ų2653.6 Ų53.614%0.13628%0.28CS..Hα-helixtrans-62.9-36.3179.8-66.7176.4000112.5I85 R86 E87 L93 I130 L133I85-L89 HydrophobicContact CG2-CD1 3.65Å; I85-L89 HydrophobicContact CG2-CG 4.14Å; I85-L89 WeakPolarHBondContact O-CG 3.37Å; I85-L89 PolarHBondContact O-N 2.86Å; R86-L89 PolarHBondContact O-N 2.87Å; E87-L89 PolarHBondContact O-N 2.62Å; L89-L93 HydrophobicContact CB-CD1 4.16Å; L89-L93 HydrophobicContact CD2-CD1 4.3Å; L89-L93 HydrophobicContact CD2-CG 4.5Å; L89-L93 VanDerWaalsContact O-CB 3.26Å; L89-L93 WeakPolarHBondContact O-CB 3.39Å; L89-L93 VanDerWaalsContact O-CG 3.3Å; L89-L93 WeakPolarHBondContact O-CG 3.47Å; L89-L93 PolarHBondContact O-N 3.42Å; L89-L93 VanDerWaalsContact O-N 3.12Å; L89-I130 HydrophobicContact CB-CD1 4.35Å; L89-I130 HydrophobicContact CB-CG1 4Å; L89-I130 HydrophobicContact CB-CG2 4.29Å; L89-I130 HydrophobicContact CD1-CG2 4.46Å; L89-L133 HydrophobicContact CD1-CB 3.74Å; L89-L133 HydrophobicContact CD1-CD1 3.98Å; L89-L133 HydrophobicContact CD2-CD1 4.11Å
90V91.9Very high88.9Confident62 Ų6255 Ų5538%0.37629%0.287SS..Hα-helixtrans-63.1-41.4173.2168.70000111.4R86 E87 G88 K126 I130R86-V90 WeakPolarHBondContact O-CB 3.5Å; R86-V90 VanDerWaalsContact O-CG2 3.26Å; R86-V90 WeakPolarHBondContact O-CG2 3.39Å; R86-V90 PolarHBondContact O-N 3.34Å; E87-V90 PolarHBondContact O-N 3.43Å; G88-V90 VanDerWaalsContact C-N 3.32Å; G88-V90 PolarHBondContact O-N 2.89Å; V90-K126 WeakPolarHBondContact O-CE 3.27Å; V90-K126 PolarHBondContact O-NZ 2.89Å; V90-I130 HydrophobicContact CB-CD1 4.44Å; V90-I130 HydrophobicContact CG2-CD1 3.74Å
91T88.1Confident89.7Confident99 Ų9951.5 Ų51.561%0.60727%0.269SS*.Hα-helixtrans-72.3-39.7-179.5-56.10000113.6E87 G88E87-T91 PolarHBondContact O-N 3.05Å; E87-T91 VanDerWaalsContact O-N 3.14Å; E87-T91 PolarHBondContact O-OG1 3.37Å; G88-T91 PolarHBondContact O-N 3.23Å; G88-T91 VanDerWaalsContact O-N 3.12Å
92F84.9Confident90.2Very high67 Ų6752.1 Ų52.129%0.29428%0.275SS..Hα-helixtrans-101.2-19.5-169.5-52.6-54.4000115.6Q55 D59 G88Q55-F92 HydrophobicContact CG-CD1 3.48Å; Q55-F92 VanDerWaalsContact CG-CD1 3.48Å; Q55-F92 HydrophobicContact CG-CE1 3.41Å; Q55-F92 VanDerWaalsContact CG-CE1 3.41Å; Q55-F92 HydrophobicContact CG-CG 4.09Å; Q55-F92 HydrophobicContact CG-CZ 3.97Å; D59-F92 HydrophobicContact CB-CE2 4.25Å; D59-F92 WeakPolarHBondContact OD1-CE2 3.43Å; D59-F92 WeakPolarHBondContact OD2-CE2 3.09Å; D59-F92 WeakPolarHBondContact OD2-CZ 3.18Å; G88-F92 WeakPolarHBondContact O-CD2 3.47Å; G88-F92 WeakPolarHBondContact O-CE2 3.45Å; G88-F92 WeakPolarHBondContact O-CG 3.46Å; G88-F92 PolarHBondContact O-N 3.05Å
93L91.4Very high90.6Very high5 Ų552.4 Ų52.43%0.02628%0.283CS..SBendtrans-78.6128.7174.4-66.4176.5000110.3L51 L89 A97 K126 L129 I130 L133L51-L93 HydrophobicContact CD1-CD2 4.1Å; L89-L93 HydrophobicContact CB-CD1 4.16Å; L89-L93 HydrophobicContact CD2-CD1 4.3Å; L89-L93 HydrophobicContact CD2-CG 4.5Å; L89-L93 VanDerWaalsContact O-CB 3.26Å; L89-L93 WeakPolarHBondContact O-CB 3.39Å; L89-L93 VanDerWaalsContact O-CG 3.3Å; L89-L93 WeakPolarHBondContact O-CG 3.47Å; L89-L93 PolarHBondContact O-N 3.42Å; L89-L93 VanDerWaalsContact O-N 3.12Å; L93-A97 HydrophobicContact CB-CB 3.98Å; L93-A97 HydrophobicContact CD2-CB 4.31Å; L93-K126 WeakPolarHBondContact O-CE 3.39Å; L93-K126 PolarHBondContact O-NZ 2.92Å; L93-L129 HydrophobicContact CD1-CD2 4.28Å; L93-I130 HydrophobicContact CD1-CD1 4.22Å; L93-I130 HydrophobicContact CD1-CG1 3.67Å; L93-L133 HydrophobicContact CD1-CD1 4.27Å
94P92.3Very high91Very high47 Ų4754 Ų5431%0.30528%0.28SS..  trans-65.4155.3171.930.4-36.5000110.3N96 A97 M100P94-N96 WeakPolarHBondContact CB-OD1 3.28Å; P94-N96 PolarHBondContact O-N 3.28Å; P94-N96 VanDerWaalsContact O-N 3.14Å; P94-A97 HydrophobicContact CG-CB 4.15Å; P94-A97 WeakPolarHBondContact O-CB 3.13Å; P94-A97 PolarHBondContact O-N 3.49Å; P94-M100 HydrophobicContact CG-SD 4.32Å
95D91.6Very high91.5Very high120 Ų12052.7 Ų52.764%0.64227%0.273SS*.THydrogen-bonded Turntrans-67.9-21.7-170.7-56.4-45.4000113.6H98 K126D95-H98 PolarHBondContact O-CE1 3.03Å; D95-H98 PolarHBondContact O-ND1 3Å; D95-K126 WeakPolarHBondContact OD1-CD 3.37Å; D95-K126 IonicContact OD1-NZ 2.68Å; D95-K126 PolarHBondContact OD1-NZ 2.84Å
96N92.6Very high92Very high84 Ų8453 Ų5345%0.44927%0.273SS..THydrogen-bonded Turntrans-865.7170.170.6-25.1000114.3P94 H98 K99 M100P94-N96 WeakPolarHBondContact CB-OD1 3.28Å; P94-N96 PolarHBondContact O-N 3.28Å; P94-N96 VanDerWaalsContact O-N 3.14Å; N96-H98 PolarHBondContact O-N 3.26Å; N96-H98 VanDerWaalsContact O-N 3.16Å; N96-K99 WeakPolarHBondContact O-CA 3.44Å; N96-K99 WeakPolarHBondContact O-CB 3.34Å; N96-K99 PolarHBondContact O-N 2.81Å; N96-M100 PolarHBondContact O-N 2.88Å; N96-M100 VanDerWaalsContact O-N 3.08Å
97A93.1Very high92.3Very high0 Ų049.5 Ų49.50%026%0.26CS..Hα-helixtrans-52.4-40-17700000112.9L93 P94 K99 M100 A101 L129L93-A97 HydrophobicContact CB-CB 3.98Å; L93-A97 HydrophobicContact CD2-CB 4.31Å; P94-A97 HydrophobicContact CG-CB 4.15Å; P94-A97 WeakPolarHBondContact O-CB 3.13Å; P94-A97 PolarHBondContact O-N 3.49Å; A97-K99 VanDerWaalsContact C-N 3.35Å; A97-K99 PolarHBondContact O-N 3.03Å; A97-M100 CarbonylContact O-C 3.49Å; A97-M100 WeakPolarHBondContact O-CA 3.4Å; A97-M100 WeakPolarHBondContact O-CB 3.31Å; A97-M100 PolarHBondContact O-N 2.94Å; A97-A101 VanDerWaalsContact O-CB 3.27Å; A97-A101 WeakPolarHBondContact O-CB 3.5Å; A97-A101 PolarHBondContact O-N 3.13Å; A97-L129 HydrophobicContact CB-CD2 3.87Å
98H94.1Very high92.6Very high27 Ų2744.5 Ų44.513%0.12524%0.237CC..Hα-helixtrans-57.6-43.3174.564-81.3000112.8D95 N96 M100 A101 S102 S125 K126 L129D95-H98 PolarHBondContact O-CE1 3.03Å; D95-H98 PolarHBondContact O-ND1 3Å; N96-H98 PolarHBondContact O-N 3.26Å; N96-H98 VanDerWaalsContact O-N 3.16Å; H98-M100 VanDerWaalsContact C-N 3.29Å; H98-M100 PolarHBondContact O-N 2.64Å; H98-A101 PolarHBondContact O-N 3.49Å; H98-S102 PolarHBondContact O-N 2.74Å; H98-S125 VanDerWaalsContact CB-O 3.23Å; H98-S125 WeakPolarHBondContact CB-O 3.2Å; H98-S125 VanDerWaalsContact CG-C 3.42Å; H98-K126 PolarHBondContact ND1-N 2.76Å; H98-L129 HydrophobicContact CB-CB 4.46Å
99K94.1Very high93.1Very high159 Ų15944.1 Ų44.169%0.69123%0.234SC*.Hα-helixtrans-69.9-25.1175.4-49.9-171-179.9-178.60113N96 A97N96-K99 WeakPolarHBondContact O-CA 3.44Å; N96-K99 WeakPolarHBondContact O-CB 3.34Å; N96-K99 PolarHBondContact O-N 2.81Å; A97-K99 VanDerWaalsContact C-N 3.35Å; A97-K99 PolarHBondContact O-N 3.03Å
100M92.3Very high93.2Very high47 Ų4742.9 Ų42.923%0.23223%0.227CC..Hα-helixtrans-79.3-32.1172.5-60.9176.974.400111.7I48 P94 N96 A97 H98 R104I48-M100 WeakPolarHBondContact CG2-O 3.47Å; P94-M100 HydrophobicContact CG-SD 4.32Å; N96-M100 PolarHBondContact O-N 2.88Å; N96-M100 VanDerWaalsContact O-N 3.08Å; A97-M100 CarbonylContact O-C 3.49Å; A97-M100 WeakPolarHBondContact O-CA 3.4Å; A97-M100 WeakPolarHBondContact O-CB 3.31Å; A97-M100 PolarHBondContact O-N 2.94Å; H98-M100 VanDerWaalsContact C-N 3.29Å; H98-M100 PolarHBondContact O-N 2.64Å; M100-R104 VanDerWaalsContact O-CZ 3.29Å; M100-R104 PolarHBondContact O-NE 2.86Å; M100-R104 PolarHBondContact O-NH2 3.36Å
101A93.9Very high93.3Very high0 Ų043.8 Ų43.80%022%0.224CC..Hα-helixtrans-82.4-39.9-17700000113.4A97 H98 G103 R104 L105 Y123 L129A97-A101 VanDerWaalsContact O-CB 3.27Å; A97-A101 WeakPolarHBondContact O-CB 3.5Å; A97-A101 PolarHBondContact O-N 3.13Å; H98-A101 PolarHBondContact O-N 3.49Å; A101-G103 PolarHBondContact O-N 2.65Å; A101-R104 CarbonylContact O-C 3.59Å; A101-R104 PolarHBondContact O-N 2.78Å; A101-L105 HydrophobicContact CB-CB 3.94Å; A101-L105 HydrophobicContact CB-CD2 3.87Å; A101-L105 PolarHBondContact O-N 3.39Å; A101-Y123 HydrophobicContact CB-CD2 3.63Å; A101-Y123 HydrophobicContact CB-CE2 3.77Å; A101-L129 HydrophobicContact CB-CD1 4.11Å; A101-L129 HydrophobicContact CB-CD2 3.95Å
102S94.7Very high93.3Very high31 Ų3139.4 Ų39.422%0.21720%0.197CC..THydrogen-bonded Turntrans-50.5136178.7-100.60000112.7H98 R104 S121 E122 Y123H98-S102 PolarHBondContact O-N 2.74Å; S102-R104 PolarHBondContact O-N 3.19Å; S102-S121 WeakPolarHBondContact CA-O 3.32Å; S102-E122 WeakPolarHBondContact CB-OE2 3.33Å; S102-E122 PolarHBondContact OG-OE2 2.97Å; S102-Y123 PolarHBondContact OG-N 2.92Å
103G92.7Very high93.4Very high32 Ų3240.3 Ų40.333%0.3321%0.211SC..THydrogen-bonded Turntrans68.7-8.5-175.600000116.1A101 S121 E122A101-G103 PolarHBondContact O-N 2.65Å; G103-S121 PolarHBondContact N-O 3.49Å; G103-E122 VanDerWaalsContact CA-OE1 3.32Å; G103-E122 WeakPolarHBondContact CA-OE1 3.27Å; G103-E122 PolarHBondContact N-OE1 3.48Å
104R93.8Very high93.2Very high92 Ų9243.4 Ų43.435%0.34723%0.228SC..THydrogen-bonded Turntrans-127.5-27.4-170.4-57.2-163.6-60.5159.53.4115.1H32 K33 I34 I48 M100 A101 S102H32-R104 WeakPolarHBondContact O-CB 3.11Å; H32-R104 WeakPolarHBondContact O-CG 3.21Å; K33-R104 CarbonylContact C-O 3.57Å; K33-R104 VanDerWaalsContact CA-O 3.26Å; K33-R104 WeakPolarHBondContact CA-O 3.33Å; I34-R104 PolarHBondContact N-O 3.28Å; I48-R104 HydrophobicContact CD1-CB 4.13Å; M100-R104 VanDerWaalsContact O-CZ 3.29Å; M100-R104 PolarHBondContact O-NE 2.86Å; M100-R104 PolarHBondContact O-NH2 3.36Å; A101-R104 CarbonylContact O-C 3.59Å; A101-R104 PolarHBondContact O-N 2.78Å; S102-R104 PolarHBondContact O-N 3.19Å
105L95.6Very high92.9Very high0 Ų041.9 Ų41.90%022%0.22CC..EExtended strand (participates in β ladder)trans-111.2117.9179.6174.163.2000109.8I34 A44 C45 A101 I107 Y123 L129I34-L105 HydrophobicContact CG2-CB 4.42Å; I34-L105 HydrophobicContact CG2-CD1 3.66Å; I34-L105 WeakPolarHBondContact O-CA 3.18Å; A44-L105 HydrophobicContact CB-CD1 3.67Å; C45-L105 HydrophobicContact CB-CD2 3.71Å; A101-L105 HydrophobicContact CB-CB 3.94Å; A101-L105 HydrophobicContact CB-CD2 3.87Å; A101-L105 PolarHBondContact O-N 3.39Å; L105-I107 HydrophobicContact CD1-CG1 4.39Å; L105-I107 HydrophobicContact CD2-CD1 4.13Å; L105-I107 HydrophobicContact CD2-CG1 4.35Å; L105-I107 HydrophobicContact CG-CD1 4.36Å; L105-I107 HydrophobicContact CG-CG1 4.05Å; L105-Y123 HydrophobicContact CB-CE2 4.33Å; L105-Y123 WeakPolarHBondContact O-CE2 3.44Å; L105-Y123 PolarHBondContact O-OH 2.73Å; L105-L129 HydrophobicContact CD2-CD1 3.8Å
106F96.6Very high92.8Very high29 Ų2939.8 Ų39.813%0.12721%0.212CC..EExtended strand (participates in β ladder)trans-110.1102.3-175.2-70.3-104000110.3K33 I34 S35 G36 L119 V120 S121 L167K33-F106 HydrophobicContact CB-CD2 4.22Å; K33-F106 HydrophobicContact CB-CE2 3.91Å; K33-F106 HydrophobicContact CD-CE2 3.75Å; K33-F106 HydrophobicContact CD-CZ 4Å; K33-F106 HydrophobicContact CG-CE2 3.84Å; I34-F106 PolarHBondContact O-N 2.92Å; S35-F106 CarbonylContact C-O 3.6Å; S35-F106 WeakPolarHBondContact CA-O 3.31Å; G36-F106 PolarHBondContact N-O 3.1Å; F106-L119 HydrophobicContact CB-CD1 4.02Å; F106-L119 HydrophobicContact CB-CD2 4.22Å; F106-L119 HydrophobicContact CB-CG 4.02Å; F106-L119 HydrophobicContact CD1-CD2 3.93Å; F106-L119 HydrophobicContact CD1-CG 4.14Å; F106-V120 CarbonylContact C-O 3.6Å; F106-V120 VanDerWaalsContact CA-O 3.26Å; F106-V120 WeakPolarHBondContact CA-O 3.1Å; F106-S121 VanDerWaalsContact CE1-CB 3.4Å; F106-L167 HydrophobicContact CB-CD2 3.97Å; F106-L167 HydrophobicContact CD1-CD2 3.85Å; F106-L167 HydrophobicContact CD2-CD1 3.87Å; F106-L167 HydrophobicContact CD2-CD2 4.32Å; F106-L167 HydrophobicContact CE1-CD2 4.46Å; F106-L167 HydrophobicContact CE2-CD1 4.33Å; F106-L167 HydrophobicContact CG-CD1 4.15Å; F106-L167 HydrophobicContact CG-CD2 3.78Å
107I97.3Very high92.9Very high0 Ų038.1 Ų38.10%020%0.203CC..EExtended strand (participates in β ladder)trans-96120.3-175.8-64.1173.5000110A41 L105 L109 L119 V120 Y123 L129 A132 L133 S136A41-I107 HydrophobicContact CB-CG1 4.29Å; A41-I107 HydrophobicContact CB-CG2 4.23Å; L105-I107 HydrophobicContact CD1-CG1 4.39Å; L105-I107 HydrophobicContact CD2-CD1 4.13Å; L105-I107 HydrophobicContact CD2-CG1 4.35Å; L105-I107 HydrophobicContact CG-CD1 4.36Å; L105-I107 HydrophobicContact CG-CG1 4.05Å; I107-L109 HydrophobicContact CG2-CD2 3.89Å; I107-L109 HydrophobicContact CG2-CG 4.38Å; I107-L119 WeakPolarHBondContact O-CA 3.39Å; I107-V120 PolarHBondContact N-O 2.74Å; I107-V120 PolarHBondContact O-N 3.17Å; I107-Y123 HydrophobicContact CD1-CE1 3.9Å; I107-Y123 WeakPolarHBondContact CD1-OH 3.32Å; I107-Y123 WeakPolarHBondContact CG1-OH 3.48Å; I107-L129 HydrophobicContact CD1-CD1 3.97Å; I107-A132 HydrophobicContact CD1-CB 4.04Å; I107-L133 HydrophobicContact CD1-CD2 3.59Å; I107-L133 HydrophobicContact CD1-CG 3.74Å; I107-L133 HydrophobicContact CG1-CD2 4.33Å; I107-S136 VanDerWaalsContact CG2-CB 3.48Å
108S96.7Very high92.9Very high0 Ų042.3 Ų42.30%022%0.221CC..EExtended strand (participates in β ladder)trans-73.6124.7172.41740000110.6G36 N117 S136 G158 D162G36-S108 WeakPolarHBondContact O-CB 3.28Å; G36-S108 PolarHBondContact O-N 2.87Å; S108-N117 PolarHBondContact OG-ND2 3.02Å; S108-S136 WeakPolarHBondContact O-CB 3.47Å; S108-S136 PolarHBondContact O-OG 3.44Å; S108-G158 VanDerWaalsContact O-CA 3.29Å; S108-G158 WeakPolarHBondContact O-CA 3.3Å; S108-G158 WeakPolarHBondContact OG-CA 3.46Å; S108-G158 PolarHBondContact OG-O 3.28Å; S108-D162 WeakPolarHBondContact CB-O 3.26Å; S108-D162 PolarHBondContact OG-O 2.77Å
109L95.5Very high93Very high0 Ų044 Ų440%023%0.23CC..EExtended strand (participates in β ladder)trans-124144.3172.5-57.3-175.5000110.3I107 N117 F118 V120 A132 C135 F150 Y155I107-L109 HydrophobicContact CG2-CD2 3.89Å; I107-L109 HydrophobicContact CG2-CG 4.38Å; L109-N117 CarbonylContact O-C 3.56Å; L109-N117 WeakPolarHBondContact O-CA 3.41Å; L109-N117 PolarHBondContact O-ND2 2.99Å; L109-F118 WeakPolarHBondContact CB-O 3.41Å; L109-F118 PolarHBondContact N-O 3.28Å; L109-F118 PolarHBondContact O-N 2.69Å; L109-V120 HydrophobicContact CD1-CG2 3.57Å; L109-V120 HydrophobicContact CG-CG2 4.09Å; L109-A132 WeakPolarHBondContact CD2-O 3.48Å; L109-C135 HydrophobicContact CD1-CB 4.34Å; L109-C135 HydrophobicContact CD2-CB 3.62Å; L109-F150 HydrophobicContact CD1-CB 4.38Å; L109-F150 HydrophobicContact CD1-CD1 4.04Å; L109-F150 HydrophobicContact CD1-CG 4.33Å; L109-Y155 HydrophobicContact CB-CD1 3.61Å; L109-Y155 HydrophobicContact CB-CE1 4.23Å; L109-Y155 HydrophobicContact CB-CG 4.09Å; L109-Y155 HydrophobicContact CD1-CD1 4.02Å; L109-Y155 HydrophobicContact CD1-CD2 4.12Å; L109-Y155 HydrophobicContact CD1-CE1 4.34Å; L109-Y155 HydrophobicContact CD1-CE2 4.42Å; L109-Y155 HydrophobicContact CD1-CG 3.93Å; L109-Y155 HydrophobicContact CG-CD1 4.46Å
110T94.5Very high93Very high0 Ų036.7 Ų36.70%020%0.2CC..EExtended strand (participates in β ladder)trans-101.2118.9169.7-55.90000109.6Y155 I156 D157 G158 W160 S161 F402T110-Y155 CarbonylContact O-C 3.4Å; T110-Y155 VanDerWaalsContact O-CA 3.32Å; T110-Y155 WeakPolarHBondContact O-CA 3.5Å; T110-I156 HydrophobicContact CG2-CD1 4.29Å; T110-I156 HydrophobicContact CG2-CG1 3.99Å; T110-I156 PolarHBondContact N-O 3.23Å; T110-I156 PolarHBondContact O-N 3.19Å; T110-D157 WeakPolarHBondContact CB-O 3.48Å; T110-D157 PolarHBondContact OG1-O 2.96Å; T110-G158 PolarHBondContact OG1-O 3.34Å; T110-W160 HydrophobicContact CG2-CB 3.95Å; T110-S161 WeakPolarHBondContact OG1-CB 3.44Å; T110-S161 PolarHBondContact OG1-N 2.75Å; T110-S161 PolarHBondContact OG1-OG 3.13Å; T110-F402 HydrophobicContact CG2-CZ 4.14Å
111R92.6Very high93.2Very high81 Ų8136 Ų3631%0.30620%0.2SC..EExtended strand (participates in β ladder)trans-73.7128.1179.6-174.9166.959.6-160.11111S113 D114 G115 V116 V153 Y155R111-S113 WeakPolarHBondContact CG-OG 3.45Å; R111-S113 PolarHBondContact O-N 3.19Å; R111-D114 WeakPolarHBondContact CG-OD1 3.35Å; R111-D114 IonicContact CZ-OD1 3.2Å; R111-D114 IonicContact CZ-OD2 2.79Å; R111-D114 IonicContact NE-OD1 2.78Å; R111-D114 PolarHBondContact NE-OD1 3.27Å; R111-D114 IonicContact NE-OD2 3.69Å; R111-D114 PolarHBondContact NE-OD2 3.18Å; R111-D114 IonicContact NH2-OD1 3.53Å; R111-D114 IonicContact NH2-OD2 2.78Å; R111-D114 PolarHBondContact NH2-OD2 2.98Å; R111-G115 VanDerWaalsContact O-CA 3.29Å; R111-G115 WeakPolarHBondContact O-CA 3.31Å; R111-G115 PolarHBondContact O-N 3.05Å; R111-V116 PolarHBondContact N-O 2.95Å; R111-V153 HydrophobicContact CG-CG1 3.95Å; R111-Y155 HydrophobicContact CB-CD1 3.95Å; R111-Y155 HydrophobicContact CB-CE1 3.73Å; R111-Y155 HydrophobicContact CG-CD1 4.44Å; R111-Y155 HydrophobicContact CG-CE1 4.05Å
112L89Confident93.3Very high7 Ų741 Ų414%0.03722%0.222CC..THydrogen-bonded Turntrans-68.3-29.9-170.4-177.861.3000114.2D114 P147 H154 I156 Q398 V399 F402L112-D114 VanDerWaalsContact C-N 3.35Å; L112-D114 PolarHBondContact O-N 2.86Å; L112-P147 HydrophobicContact CD2-CB 4.42Å; L112-P147 HydrophobicContact CD2-CG 3.73Å; L112-H154 HydrophobicContact CB-CB 4.13Å; L112-H154 WeakPolarHBondContact CB-O 3.42Å; L112-H154 HydrophobicContact CD2-CB 3.93Å; L112-H154 PolarHBondContact N-O 3.42Å; L112-H154 VanDerWaalsContact N-O 3.1Å; L112-I156 HydrophobicContact CD1-CG2 4.04Å; L112-Q398 HydrophobicContact CD2-CB 4.14Å; L112-V399 HydrophobicContact CD1-CG2 4.2Å; L112-V399 HydrophobicContact CD2-CG2 4.17Å; L112-F402 HydrophobicContact CD1-CB 3.73Å; L112-F402 HydrophobicContact CD1-CD1 4.29Å; L112-F402 HydrophobicContact CD1-CD2 4.46Å; L112-F402 HydrophobicContact CD1-CG 3.88Å; L112-F402 WeakPolarHBondContact O-CD2 3.06Å
113S86.7Confident93.3Very high86 Ų8639.9 Ų39.960%0.60121%0.214SC*.THydrogen-bonded Turntrans-66.7-32.7-175.146.80000114.4R111R111-S113 WeakPolarHBondContact CG-OG 3.45Å; R111-S113 PolarHBondContact O-N 3.19Å
114D86.8Confident93.3Very high70 Ų7045.9 Ų45.937%0.37423%0.231SC..THydrogen-bonded Turntrans-144.1-13.4-16558.8-29.5000114.2R111 L112 V116R111-D114 WeakPolarHBondContact CG-OD1 3.35Å; R111-D114 IonicContact CZ-OD1 3.2Å; R111-D114 IonicContact CZ-OD2 2.79Å; R111-D114 IonicContact NE-OD1 2.78Å; R111-D114 PolarHBondContact NE-OD1 3.27Å; R111-D114 IonicContact NE-OD2 3.69Å; R111-D114 PolarHBondContact NE-OD2 3.18Å; R111-D114 IonicContact NH2-OD1 3.53Å; R111-D114 IonicContact NH2-OD2 2.78Å; R111-D114 PolarHBondContact NH2-OD2 2.98Å; L112-D114 VanDerWaalsContact C-N 3.35Å; L112-D114 PolarHBondContact O-N 2.86Å; D114-V116 VanDerWaalsContact C-N 3.31Å; D114-V116 HydrophobicContact CB-CG2 4.38Å; D114-V116 PolarHBondContact O-N 2.97Å; D114-V116 WeakPolarHBondContact OD2-CG2 3.42Å
115G85.8Confident93.4Very high14 Ų1443.8 Ų43.814%0.14423%0.23CC..  trans79.4917800000115.6R111 F402R111-G115 VanDerWaalsContact O-CA 3.29Å; R111-G115 WeakPolarHBondContact O-CA 3.31Å; R111-G115 PolarHBondContact O-N 3.05Å; G115-F402 VanDerWaalsContact CA-CE2 3.5Å
116V91Very high93.4Very high77 Ų7745.4 Ų45.447%0.46724%0.237SC..  trans-72.5140.2177.5175.90000109.7R111 D114R111-V116 PolarHBondContact N-O 2.95Å; D114-V116 VanDerWaalsContact C-N 3.31Å; D114-V116 HydrophobicContact CB-CG2 4.38Å; D114-V116 PolarHBondContact O-N 2.97Å; D114-V116 WeakPolarHBondContact OD2-CG2 3.42Å
117N94Very high93.3Very high49 Ų4947.6 Ų47.626%0.26225%0.25SS..EExtended strand (participates in β ladder)trans-69.5138.9172.8-171.2-96.8000110.7S108 L109 S161S108-N117 PolarHBondContact OG-ND2 3.02Å; L109-N117 CarbonylContact O-C 3.56Å; L109-N117 WeakPolarHBondContact O-CA 3.41Å; L109-N117 PolarHBondContact O-ND2 2.99Å; N117-S161 WeakPolarHBondContact CA-OG 3.3Å; N117-S161 WeakPolarHBondContact CB-OG 3.29Å; N117-S161 PolarHBondContact ND2-OG 2.98Å
118F94Very high93.1Very high88 Ų8848.5 Ų48.539%0.38626%0.255SS..EExtended strand (participates in β ladder)trans-128.1105.1171.5-171.5-121.2000109.3L109 V120 F150 Y155L109-F118 WeakPolarHBondContact CB-O 3.41Å; L109-F118 PolarHBondContact N-O 3.28Å; L109-F118 PolarHBondContact O-N 2.69Å; F118-V120 HydrophobicContact CD1-CG2 3.66Å; F118-V120 HydrophobicContact CE1-CG2 3.72Å; F118-V120 PolarHBondContact O-N 3.28Å; F118-F150 HydrophobicContact CE1-CE1 4.25Å; F118-Y155 HydrophobicContact CB-CE1 3.87Å; F118-Y155 AromaticContact CD1-CE1 3.9Å; F118-Y155 HydrophobicContact CD1-CE1 3.9Å; F118-Y155 AromaticContact CD1-CZ 3.84Å; F118-Y155 WeakPolarHBondContact CD1-OH 3.32Å; F118-Y155 HydrophobicContact CG-CE1 4.22Å
119L95.1Very high93.1Very high61 Ų6148.5 Ų48.532%0.31926%0.255SS..EExtended strand (participates in β ladder)trans-87.499-179.4-168.869.4000109.7F106 I107 P165 L167F106-L119 HydrophobicContact CB-CD1 4.02Å; F106-L119 HydrophobicContact CB-CD2 4.22Å; F106-L119 HydrophobicContact CB-CG 4.02Å; F106-L119 HydrophobicContact CD1-CD2 3.93Å; F106-L119 HydrophobicContact CD1-CG 4.14Å; I107-L119 WeakPolarHBondContact O-CA 3.39Å; L119-P165 HydrophobicContact CD1-CB 3.77Å; L119-P165 HydrophobicContact CD1-CG 4.1Å; L119-L167 HydrophobicContact CD2-CD2 3.89Å
120V95.1Very high93.1Very high7 Ų748.5 Ų48.54%0.04226%0.255CS..EExtended strand (participates in β ladder)trans-79.1128.1-177.5-176.80000110.1F106 I107 L109 F118 Y123 F150F106-V120 CarbonylContact C-O 3.6Å; F106-V120 VanDerWaalsContact CA-O 3.26Å; F106-V120 WeakPolarHBondContact CA-O 3.1Å; I107-V120 PolarHBondContact N-O 2.74Å; I107-V120 PolarHBondContact O-N 3.17Å; L109-V120 HydrophobicContact CD1-CG2 3.57Å; L109-V120 HydrophobicContact CG-CG2 4.09Å; F118-V120 HydrophobicContact CD1-CG2 3.66Å; F118-V120 HydrophobicContact CE1-CG2 3.72Å; F118-V120 PolarHBondContact O-N 3.28Å; V120-Y123 HydrophobicContact CB-CE1 4.37Å; V120-Y123 HydrophobicContact CG1-CD1 4.16Å; V120-Y123 HydrophobicContact CG1-CE1 3.55Å; V120-Y123 PolarHBondContact O-OH 2.77Å; V120-F150 HydrophobicContact CB-CE1 4.45Å; V120-F150 HydrophobicContact CG1-CE1 3.85Å; V120-F150 HydrophobicContact CG1-CZ 3.6Å; V120-F150 HydrophobicContact CG2-CD1 4.18Å; V120-F150 HydrophobicContact CG2-CE1 3.65Å; V120-F150 HydrophobicContact CG2-CZ 4.21Å
121S95.4Very high93.1Very high33 Ų3350.5 Ų50.523%0.23127%0.266CS..  trans-118.8-9.3175.870.70000114.9S102 G103 F106S102-S121 WeakPolarHBondContact CA-O 3.32Å; G103-S121 PolarHBondContact N-O 3.49Å; F106-S121 VanDerWaalsContact CE1-CB 3.4Å
122E95.4Very high93.2Very high103 Ų10346.6 Ų46.648%0.48125%0.251SS..  trans-128.7132.9-171.2-68.3-53.2138.100112.1S102 G103S102-E122 WeakPolarHBondContact CB-OE2 3.33Å; S102-E122 PolarHBondContact OG-OE2 2.97Å; G103-E122 VanDerWaalsContact CA-OE1 3.32Å; G103-E122 WeakPolarHBondContact CA-OE1 3.27Å; G103-E122 PolarHBondContact N-OE1 3.48Å
123Y95.5Very high93.5Very high9 Ų946.3 Ų46.34%0.03525%0.249CC..  trans-132.6120.2-171.9-47.2-82.3000111.3A101 S102 L105 I107 V120 D128 L129 A132A101-Y123 HydrophobicContact CB-CD2 3.63Å; A101-Y123 HydrophobicContact CB-CE2 3.77Å; S102-Y123 PolarHBondContact OG-N 2.92Å; L105-Y123 HydrophobicContact CB-CE2 4.33Å; L105-Y123 WeakPolarHBondContact O-CE2 3.44Å; L105-Y123 PolarHBondContact O-OH 2.73Å; I107-Y123 HydrophobicContact CD1-CE1 3.9Å; I107-Y123 WeakPolarHBondContact CD1-OH 3.32Å; I107-Y123 WeakPolarHBondContact CG1-OH 3.48Å; V120-Y123 HydrophobicContact CB-CE1 4.37Å; V120-Y123 HydrophobicContact CG1-CD1 4.16Å; V120-Y123 HydrophobicContact CG1-CE1 3.55Å; V120-Y123 PolarHBondContact O-OH 2.77Å; Y123-D128 WeakPolarHBondContact CA-OD2 3.45Å; Y123-L129 HydrophobicContact CD1-CB 3.95Å; Y123-L129 HydrophobicContact CD1-CD1 3.81Å; Y123-L129 HydrophobicContact CD2-CD1 4.24Å; Y123-L129 HydrophobicContact CE1-CD1 3.76Å; Y123-L129 HydrophobicContact CE2-CD1 4.23Å; Y123-L129 HydrophobicContact CG-CB 4.04Å; Y123-L129 HydrophobicContact CG-CD1 4.04Å; Y123-A132 HydrophobicContact CD1-CB 4.36Å; Y123-A132 HydrophobicContact CE1-CB 3.92Å
124K93.4Very high93.9Very high158 Ų15842.4 Ų42.469%0.68722%0.222SC*.SBendtrans-77.6-27.4-174-65.5163.8-178.7158.30113.3D128 Q151K124-D128 HydrophobicContact CB-CB 4.42Å; K124-D128 PolarHBondContact N-OD2 2.91Å; K124-Q151 VanDerWaalsContact NZ-CD 3.34Å
125S95.2Very high94.2Very high47 Ų4739.1 Ų39.133%0.32920%0.204SC..SBendtrans-154.3170.7-178.374.40000111.5H98 D127 D128 L129H98-S125 VanDerWaalsContact CB-O 3.23Å; H98-S125 WeakPolarHBondContact CB-O 3.2Å; H98-S125 VanDerWaalsContact CG-C 3.42Å; S125-D127 VanDerWaalsContact C-N 3.3Å; S125-D127 PolarHBondContact O-N 2.93Å; S125-D127 PolarHBondContact OG-N 2.67Å; S125-D128 WeakPolarHBondContact O-CB 3.44Å; S125-D128 PolarHBondContact O-N 3.33Å; S125-D128 PolarHBondContact OG-N 3.34Å; S125-D128 VanDerWaalsContact OG-N 3.09Å; S125-L129 PolarHBondContact O-N 3.08Å; S125-L129 VanDerWaalsContact O-N 3.15Å
126K94.7Very high94.6Very high34 Ų3438.4 Ų38.415%0.14820%0.197CC..Hα-helixtrans-58.5-41.4173169.7165.6157.8176.90111.4V90 L93 D95 H98 L129 I130V90-K126 WeakPolarHBondContact O-CE 3.27Å; V90-K126 PolarHBondContact O-NZ 2.89Å; L93-K126 WeakPolarHBondContact O-CE 3.39Å; L93-K126 PolarHBondContact O-NZ 2.92Å; D95-K126 WeakPolarHBondContact OD1-CD 3.37Å; D95-K126 IonicContact OD1-NZ 2.68Å; D95-K126 PolarHBondContact OD1-NZ 2.84Å; H98-K126 PolarHBondContact ND1-N 2.76Å; K126-L129 PolarHBondContact O-N 3.4Å; K126-I130 HydrophobicContact CG-CD1 3.71Å; K126-I130 HydrophobicContact CG-CG1 4.48Å; K126-I130 WeakPolarHBondContact O-CB 3.26Å; K126-I130 WeakPolarHBondContact O-CG1 3.27Å; K126-I130 PolarHBondContact O-N 3.5Å
127D94.5Very high94.7Very high76 Ų7635.2 Ų35.241%0.40618%0.179SC..Hα-helixtrans-64.3-40.5174-75.4-80.1000113.1R86 S125 L129 I130 D131R86-D127 IonicContact CZ-OD1 2.83Å; R86-D127 IonicContact NH1-OD1 2.76Å; R86-D127 PolarHBondContact NH1-OD1 3.28Å; R86-D127 IonicContact NH2-OD1 2.93Å; R86-D127 PolarHBondContact NH2-OD1 2.95Å; S125-D127 VanDerWaalsContact C-N 3.3Å; S125-D127 PolarHBondContact O-N 2.93Å; S125-D127 PolarHBondContact OG-N 2.67Å; D127-L129 VanDerWaalsContact C-N 3.32Å; D127-L129 PolarHBondContact O-N 3.48Å; D127-I130 CarbonylContact O-C 3.58Å; D127-I130 PolarHBondContact O-N 3.35Å; D127-I130 VanDerWaalsContact O-N 3.07Å; D127-D131 WeakPolarHBondContact O-CB 3.25Å; D127-D131 PolarHBondContact O-N 3.47Å
128D94.8Very high94.5Very high19 Ų1932.9 Ų32.910%0.10217%0.166CC..Hα-helixtrans-60-41.4177.9-16352.1000111.2Y123 K124 S125 A132 F150 Q151Y123-D128 WeakPolarHBondContact CA-OD2 3.45Å; K124-D128 HydrophobicContact CB-CB 4.42Å; K124-D128 PolarHBondContact N-OD2 2.91Å; S125-D128 WeakPolarHBondContact O-CB 3.44Å; S125-D128 PolarHBondContact O-N 3.33Å; S125-D128 PolarHBondContact OG-N 3.34Å; S125-D128 VanDerWaalsContact OG-N 3.09Å; D128-A132 WeakPolarHBondContact O-CB 3.48Å; D128-A132 PolarHBondContact O-N 3.22Å; D128-A132 VanDerWaalsContact O-N 3.08Å; D128-F150 VanDerWaalsContact O-CE2 3.27Å; D128-F150 WeakPolarHBondContact O-CE2 3.43Å; D128-F150 VanDerWaalsContact OD1-CE2 3.24Å; D128-F150 WeakPolarHBondContact OD1-CE2 3.41Å; D128-Q151 VanDerWaalsContact CG-NE2 3.34Å; D128-Q151 VanDerWaalsContact OD1-CG 3.24Å; D128-Q151 WeakPolarHBondContact OD1-CG 3.45Å; D128-Q151 PolarHBondContact OD1-NE2 3.26Å; D128-Q151 PolarHBondContact OD2-NE2 3.06Å
129L95.8Very high94.1Very high0 Ų030.4 Ų30.40%016%0.157CC..Hα-helixtrans-65.8-41.6171.317361.6000112.8L93 A97 H98 A101 L105 I107 Y123 S125 K126 D127 A132 L133L93-L129 HydrophobicContact CD1-CD2 4.28Å; A97-L129 HydrophobicContact CB-CD2 3.87Å; H98-L129 HydrophobicContact CB-CB 4.46Å; A101-L129 HydrophobicContact CB-CD1 4.11Å; A101-L129 HydrophobicContact CB-CD2 3.95Å; L105-L129 HydrophobicContact CD2-CD1 3.8Å; I107-L129 HydrophobicContact CD1-CD1 3.97Å; Y123-L129 HydrophobicContact CD1-CB 3.95Å; Y123-L129 HydrophobicContact CD1-CD1 3.81Å; Y123-L129 HydrophobicContact CD2-CD1 4.24Å; Y123-L129 HydrophobicContact CE1-CD1 3.76Å; Y123-L129 HydrophobicContact CE2-CD1 4.23Å; Y123-L129 HydrophobicContact CG-CB 4.04Å; Y123-L129 HydrophobicContact CG-CD1 4.04Å; S125-L129 PolarHBondContact O-N 3.08Å; S125-L129 VanDerWaalsContact O-N 3.15Å; K126-L129 PolarHBondContact O-N 3.4Å; D127-L129 VanDerWaalsContact C-N 3.32Å; D127-L129 PolarHBondContact O-N 3.48Å; L129-A132 PolarHBondContact O-N 3.45Å; L129-L133 HydrophobicContact CD1-CD1 4.16Å; L129-L133 HydrophobicContact CD1-CG 4.32Å; L129-L133 HydrophobicContact CG-CD1 4.2Å; L129-L133 WeakPolarHBondContact O-CG 3.46Å; L129-L133 PolarHBondContact O-N 3.14Å
130I95.3Very high93.3Very high0 Ų028.1 Ų28.10%015%0.146CC..Hα-helixtrans-66.1-41.5179.6-73.1171.6000111R86 L89 V90 L93 K126 D127 L133 T134R86-I130 HydrophobicContact CG-CG2 3.41Å; R86-I130 VanDerWaalsContact CG-CG2 3.41Å; L89-I130 HydrophobicContact CB-CD1 4.35Å; L89-I130 HydrophobicContact CB-CG1 4Å; L89-I130 HydrophobicContact CB-CG2 4.29Å; L89-I130 HydrophobicContact CD1-CG2 4.46Å; V90-I130 HydrophobicContact CB-CD1 4.44Å; V90-I130 HydrophobicContact CG2-CD1 3.74Å; L93-I130 HydrophobicContact CD1-CD1 4.22Å; L93-I130 HydrophobicContact CD1-CG1 3.67Å; K126-I130 HydrophobicContact CG-CD1 3.71Å; K126-I130 HydrophobicContact CG-CG1 4.48Å; K126-I130 WeakPolarHBondContact O-CB 3.26Å; K126-I130 WeakPolarHBondContact O-CG1 3.27Å; K126-I130 PolarHBondContact O-N 3.5Å; D127-I130 CarbonylContact O-C 3.58Å; D127-I130 PolarHBondContact O-N 3.35Å; D127-I130 VanDerWaalsContact O-N 3.07Å; I130-L133 PolarHBondContact O-N 2.99Å; I130-T134 WeakPolarHBondContact O-CB 3.45Å; I130-T134 PolarHBondContact O-N 3.11Å; I130-T134 PolarHBondContact O-OG1 2.93Å
131D94.6Very high92.4Very high41 Ų4133 Ų3322%0.21917%0.166CC..Hα-helixtrans-71.4-34.1179-69.6-30.5000111.1R86 D127 T134 C135R86-D131 IonicContact CZ-OD1 2.83Å; R86-D131 IonicContact NE-OD1 3.22Å; R86-D131 PolarHBondContact NE-OD1 2.86Å; R86-D131 IonicContact NH2-OD1 3.36Å; R86-D131 PolarHBondContact NH2-OD1 3.01Å; R86-D131 IonicContact NH2-OD2 2.82Å; R86-D131 PolarHBondContact NH2-OD2 3.46Å; D127-D131 WeakPolarHBondContact O-CB 3.25Å; D127-D131 PolarHBondContact O-N 3.47Å; D131-T134 PolarHBondContact O-N 2.65Å; D131-C135 WeakPolarHBondContact O-CB 3.25Å; D131-C135 PolarHBondContact O-N 2.83Å; D131-C135 PolarHBondContact O-SG 3.15Å
132A95.8Very high91.3Very high0 Ų032.4 Ų32.40%016%0.159CC..Hα-helixtrans-61-50.7168.200000112.3I107 L109 Y123 D128 L129 T134 C135 S136 F150I107-A132 HydrophobicContact CD1-CB 4.04Å; L109-A132 WeakPolarHBondContact CD2-O 3.48Å; Y123-A132 HydrophobicContact CD1-CB 4.36Å; Y123-A132 HydrophobicContact CE1-CB 3.92Å; D128-A132 WeakPolarHBondContact O-CB 3.48Å; D128-A132 PolarHBondContact O-N 3.22Å; D128-A132 VanDerWaalsContact O-N 3.08Å; L129-A132 PolarHBondContact O-N 3.45Å; A132-T134 VanDerWaalsContact C-N 3.27Å; A132-T134 PolarHBondContact O-N 3.15Å; A132-C135 PolarHBondContact O-N 3.17Å; A132-S136 WeakPolarHBondContact O-CB 3.35Å; A132-S136 PolarHBondContact O-N 3.45Å; A132-F150 HydrophobicContact CB-CD2 3.86Å; A132-F150 HydrophobicContact CB-CE2 3.84Å; A132-F150 HydrophobicContact CB-CZ 4.47Å
133L95.1Very high90.3Very high0 Ų027.6 Ų27.60%014%0.137CC..Hα-helixtrans-60.3-37.7176.3-73.7167.6000112.4A41 M42 C45 L89 L93 I107 L129 I130 S136 A137A41-L133 HydrophobicContact CB-CD2 4.04Å; M42-L133 HydrophobicContact CG-CD2 4.36Å; C45-L133 HydrophobicContact CB-CD1 4.21Å; C45-L133 HydrophobicContact CB-CD2 4.18Å; L89-L133 HydrophobicContact CD1-CB 3.74Å; L89-L133 HydrophobicContact CD1-CD1 3.98Å; L89-L133 HydrophobicContact CD2-CD1 4.11Å; L93-L133 HydrophobicContact CD1-CD1 4.27Å; I107-L133 HydrophobicContact CD1-CD2 3.59Å; I107-L133 HydrophobicContact CD1-CG 3.74Å; I107-L133 HydrophobicContact CG1-CD2 4.33Å; L129-L133 HydrophobicContact CD1-CD1 4.16Å; L129-L133 HydrophobicContact CD1-CG 4.32Å; L129-L133 HydrophobicContact CG-CD1 4.2Å; L129-L133 WeakPolarHBondContact O-CG 3.46Å; L129-L133 PolarHBondContact O-N 3.14Å; I130-L133 PolarHBondContact O-N 2.99Å; L133-S136 PolarHBondContact O-N 3.15Å; L133-A137 PolarHBondContact O-N 3.45Å
134T93.6Very high89.4Confident5 Ų528.2 Ų28.23%0.03115%0.146CC..Hα-helixtrans-70-39.3178.8-62.50000111.7T82 I130 D131 A132 F138 P148T82-T134 HydrophobicContact CG2-CG2 3.35Å; I130-T134 WeakPolarHBondContact O-CB 3.45Å; I130-T134 PolarHBondContact O-N 3.11Å; I130-T134 PolarHBondContact O-OG1 2.93Å; D131-T134 PolarHBondContact O-N 2.65Å; A132-T134 VanDerWaalsContact C-N 3.27Å; A132-T134 PolarHBondContact O-N 3.15Å; T134-F138 PolarHBondContact O-N 3.28Å; T134-P148 HydrophobicContact CG2-CB 4.38Å; T134-P148 HydrophobicContact CG2-CG 4.43Å
135C94.2Very high88.3Confident0 Ų023 Ų230%013%0.128CC..Hα-helixtrans-62.2-45.5170-70.50000111.5L109 D131 A132 A137 F138 P148 I156 D157L109-C135 HydrophobicContact CD1-CB 4.34Å; L109-C135 HydrophobicContact CD2-CB 3.62Å; D131-C135 WeakPolarHBondContact O-CB 3.25Å; D131-C135 PolarHBondContact O-N 2.83Å; D131-C135 PolarHBondContact O-SG 3.15Å; A132-C135 PolarHBondContact O-N 3.17Å; C135-A137 PolarHBondContact O-N 3.24Å; C135-A137 VanDerWaalsContact O-N 3.15Å; C135-F138 PolarHBondContact O-N 3.26Å; C135-F138 VanDerWaalsContact O-N 3.08Å; C135-P148 HydrophobicContact CB-CG 4.21Å; C135-P148 VanDerWaalsContact SG-CG 3.59Å; C135-I156 CarbonylContact O-C 3.55Å; C135-I156 VanDerWaalsContact O-C 3.25Å; C135-D157 PolarHBondContact O-N 2.79Å
136S94.7Very high87.7Confident0 Ų023.7 Ų23.70%013%0.13CC..Hα-helixtrans-63.2-20.7-177.4-162.30000113.8S38 I107 S108 A132 L133 D157 G158S38-S136 WeakPolarHBondContact CA-O 3.3Å; S38-S136 WeakPolarHBondContact CB-O 3.13Å; S38-S136 PolarHBondContact N-O 3.32Å; S38-S136 PolarHBondContact N-OG 3.25Å; I107-S136 VanDerWaalsContact CG2-CB 3.48Å; S108-S136 WeakPolarHBondContact O-CB 3.47Å; S108-S136 PolarHBondContact O-OG 3.44Å; A132-S136 WeakPolarHBondContact O-CB 3.35Å; A132-S136 PolarHBondContact O-N 3.45Å; L133-S136 PolarHBondContact O-N 3.15Å; S136-D157 VanDerWaalsContact O-CA 3.23Å; S136-D157 WeakPolarHBondContact O-CA 3.3Å; S136-D157 WeakPolarHBondContact O-CB 3.36Å; S136-G158 PolarHBondContact O-N 3.14Å
137A92Very high87.2Confident9 Ų922.2 Ų22.27%0.07412%0.124CC..THydrogen-bonded Turntrans-111.814.2176.100000114.1M42 I85 L133 C135 I139 S143M42-A137 HydrophobicContact CE-CB 3.48Å; M42-A137 VanDerWaalsContact CE-CB 3.48Å; I85-A137 HydrophobicContact CD1-CB 4.32Å; L133-A137 PolarHBondContact O-N 3.45Å; C135-A137 PolarHBondContact O-N 3.24Å; C135-A137 VanDerWaalsContact O-N 3.15Å; A137-I139 PolarHBondContact O-N 3.18Å; A137-S143 PolarHBondContact O-OG 2.83Å
138F90.8Very high87Confident1 Ų119.7 Ų19.70%0.00411%0.112CC..  trans-84.392175.5-174-94.5000111.1T134 C135 P140 G144 V146 P147 P148 I156 D157T134-F138 PolarHBondContact O-N 3.28Å; C135-F138 PolarHBondContact O-N 3.26Å; C135-F138 VanDerWaalsContact O-N 3.08Å; F138-P140 HydrophobicContact CD1-CG 4.36Å; F138-P140 HydrophobicContact CE1-CB 4.19Å; F138-P140 HydrophobicContact CE1-CG 4.12Å; F138-P140 WeakPolarHBondContact O-CD 3.35Å; F138-G144 VanDerWaalsContact CZ-O 3.3Å; F138-G144 WeakPolarHBondContact CZ-O 3.36Å; F138-V146 WeakPolarHBondContact CE2-O 3.5Å; F138-V146 WeakPolarHBondContact CZ-O 3.46Å; F138-P147 HydrophobicContact CD1-CB 3.97Å; F138-P147 HydrophobicContact CE1-CB 3.7Å; F138-P147 HydrophobicContact CZ-CB 4.28Å; F138-P148 HydrophobicContact CB-CG 3.92Å; F138-P148 VanDerWaalsContact CD2-CD 3.47Å; F138-P148 HydrophobicContact CD2-CG 4.37Å; F138-P148 HydrophobicContact CG-CG 4.16Å; F138-I156 HydrophobicContact CD1-CB 4.34Å; F138-I156 HydrophobicContact CD1-CG2 4.04Å; F138-I156 HydrophobicContact CE1-CG2 4.48Å; F138-D157 WeakPolarHBondContact O-CB 3.43Å; F138-D157 PolarHBondContact O-N 2.99Å
139I85.9Confident86.8Confident36 Ų3623.8 Ų23.819%0.18513%0.131CC..  trans-82.2118168.7-56.7175.9000107.5A137 Y142 S143 D157A137-I139 PolarHBondContact O-N 3.18Å; I139-Y142 HydrophobicContact CB-CD1 4.14Å; I139-Y142 HydrophobicContact CB-CG 4.45Å; I139-Y142 HydrophobicContact CD1-CD1 4.2Å; I139-Y142 HydrophobicContact CD1-CE1 4.42Å; I139-Y142 HydrophobicContact CG2-CD1 4.49Å; I139-Y142 HydrophobicContact CG2-CG 4.36Å; I139-Y142 PolarHBondContact O-N 3.37Å; I139-S143 PolarHBondContact N-OG 3.23Å; I139-S143 WeakPolarHBondContact O-CB 3.3Å; I139-S143 PolarHBondContact O-N 3Å; I139-D157 HydrophobicContact CG1-CB 4.12Å
140P78.1Confident86.6Confident13 Ų1324 Ų248%0.08413%0.132CC..BIsolated β-bridgetrans-60.6146.2-177-23.534.2000113.2F138 Y142 I156 V399F138-P140 HydrophobicContact CD1-CG 4.36Å; F138-P140 HydrophobicContact CE1-CB 4.19Å; F138-P140 HydrophobicContact CE1-CG 4.12Å; F138-P140 WeakPolarHBondContact O-CD 3.35Å; P140-Y142 PolarHBondContact O-N 3.44Å; P140-I156 HydrophobicContact CG-CB 4.21Å; P140-I156 HydrophobicContact CG-CD1 4.21Å; P140-I156 HydrophobicContact CG-CG2 3.96Å; P140-V399 HydrophobicContact CB-CG1 3.58Å; P140-V399 HydrophobicContact CG-CG1 4.26Å
141F74.9Confident86.4Confident108 Ų10828.5 Ų28.547%0.47415%0.153SC..THydrogen-bonded Turntrans63-24.4-171.6-54.9-81.8000116G144 T145 V399 L403F141-G144 VanDerWaalsContact CA-O 3.31Å; F141-G144 WeakPolarHBondContact CA-O 3.4Å; F141-G144 PolarHBondContact N-O 3.29Å; F141-T145 HydrophobicContact CD1-CG2 4.28Å; F141-V399 HydrophobicContact CD2-CG1 4.4Å; F141-V399 HydrophobicContact CE2-CG1 3.66Å; F141-V399 HydrophobicContact CZ-CG1 4.08Å; F141-L403 HydrophobicContact CD2-CD1 4.31Å; F141-L403 HydrophobicContact CE2-CD1 3.77Å
142Y73.2Confident86.1Confident22 Ų2229.7 Ų29.79%0.08618%0.175CC..THydrogen-bonded Turntrans-92.1-50.9-179.1179.6-85.9000112.4F10 P74 L75 L81 I139 P140 L217F10-Y142 WeakPolarHBondContact CD2-OH 3.36Å; F10-Y142 WeakPolarHBondContact CE2-OH 3.44Å; P74-Y142 HydrophobicContact CB-CD2 4.31Å; P74-Y142 HydrophobicContact CB-CE1 4.34Å; P74-Y142 HydrophobicContact CB-CE2 3.6Å; P74-Y142 HydrophobicContact CG-CE2 4.01Å; L75-Y142 HydrophobicContact CD2-CD2 3.8Å; L81-Y142 HydrophobicContact CD2-CD1 4.05Å; L81-Y142 HydrophobicContact CD2-CE1 3.61Å; I139-Y142 HydrophobicContact CB-CD1 4.14Å; I139-Y142 HydrophobicContact CB-CG 4.45Å; I139-Y142 HydrophobicContact CD1-CD1 4.2Å; I139-Y142 HydrophobicContact CD1-CE1 4.42Å; I139-Y142 HydrophobicContact CG2-CD1 4.49Å; I139-Y142 HydrophobicContact CG2-CG 4.36Å; I139-Y142 PolarHBondContact O-N 3.37Å; P140-Y142 PolarHBondContact O-N 3.44Å; Y142-L217 WeakPolarHBondContact CE2-O 3.14Å; Y142-L217 PolarHBondContact OH-O 3.01Å
143S75.2Confident86Confident1 Ų132.4 Ų32.41%0.00719%0.191CC..THydrogen-bonded Turntrans-81-19.9175.1-58.50000112.6N80 T82 A137 I139N80-S143 PolarHBondContact OD1-O 2.74Å; T82-S143 PolarHBondContact OG1-O 3.02Å; A137-S143 PolarHBondContact O-OG 2.83Å; I139-S143 PolarHBondContact N-OG 3.23Å; I139-S143 WeakPolarHBondContact O-CB 3.3Å; I139-S143 PolarHBondContact O-N 3Å
144G74.7Confident85.8Confident23 Ų2335 Ų3524%0.23720%0.203CC..BIsolated β-bridgetrans159.2-177.4179.800000111.8F138 F141F138-G144 VanDerWaalsContact CZ-O 3.3Å; F138-G144 WeakPolarHBondContact CZ-O 3.36Å; F141-G144 VanDerWaalsContact CA-O 3.31Å; F141-G144 WeakPolarHBondContact CA-O 3.4Å; F141-G144 PolarHBondContact N-O 3.29Å
145T71Confident85.8Confident49 Ų4935.3 Ų35.330%0.30120%0.204SC..SBendtrans-110.6-11.4-179.953.60000114.3F141 F392F141-T145 HydrophobicContact CD1-CG2 4.28Å; T145-F392 HydrophobicContact CG2-CE2 4.08Å
146V81.7Confident85.7Confident61 Ų6135.3 Ų35.337%0.3720%0.204SC..SBendtrans-110.8115.2173.6-179.30000107.5F138F138-V146 WeakPolarHBondContact CE2-O 3.5Å; F138-V146 WeakPolarHBondContact CZ-O 3.46Å
147P85.4Confident85.6Confident3 Ų335.8 Ų35.82%0.01921%0.206CC..  trans-69.2139.1178.826.1-30.2000110.7L112 F138 H154 I156 V399L112-P147 HydrophobicContact CD2-CB 4.42Å; L112-P147 HydrophobicContact CD2-CG 3.73Å; F138-P147 HydrophobicContact CD1-CB 3.97Å; F138-P147 HydrophobicContact CE1-CB 3.7Å; F138-P147 HydrophobicContact CZ-CB 4.28Å; P147-H154 HydrophobicContact CG-CB 4.36Å; P147-H154 PolarHBondContact O-CE1 2.86Å; P147-H154 PolarHBondContact O-ND1 2.93Å; P147-I156 HydrophobicContact CB-CG2 4.36Å; P147-V399 HydrophobicContact CG-CG2 4.16Å
148P89.8Confident85.5Confident23 Ų2335.3 Ų35.315%0.14920%0.203CC..  trans-62.1167.4173.428.7-35.9000111.4T134 C135 F138 H154 Y155T134-P148 HydrophobicContact CG2-CB 4.38Å; T134-P148 HydrophobicContact CG2-CG 4.43Å; C135-P148 HydrophobicContact CB-CG 4.21Å; C135-P148 VanDerWaalsContact SG-CG 3.59Å; F138-P148 HydrophobicContact CB-CG 3.92Å; F138-P148 VanDerWaalsContact CD2-CD 3.47Å; F138-P148 HydrophobicContact CD2-CG 4.37Å; F138-P148 HydrophobicContact CG-CG 4.16Å; P148-H154 PolarHBondContact O-ND1 2.88Å; P148-Y155 PolarHBondContact O-N 3.29Å
149M90.8Very high85.4Confident105 Ų10535.9 Ų35.952%0.51721%0.209SC..EExtended strand (participates in β ladder)trans-115.6139.3173.2-66.9-178.2-69.700109.8V153 H154M149-V153 CarbonylContact C-O 3.4Å; M149-V153 VanDerWaalsContact CA-O 3.27Å; M149-V153 WeakPolarHBondContact CA-O 3.37Å; M149-H154 WeakPolarHBondContact CG-CE1 3.24Å; M149-H154 WeakPolarHBondContact CG-ND1 3.48Å
150F92.2Very high85.4Confident4 Ų438.4 Ų38.42%0.01822%0.216CC..EExtended strand (participates in β ladder)trans-117.2124.5164.9174-106.2000108L109 F118 V120 D128 A132 G152 V153 Y155L109-F150 HydrophobicContact CD1-CB 4.38Å; L109-F150 HydrophobicContact CD1-CD1 4.04Å; L109-F150 HydrophobicContact CD1-CG 4.33Å; F118-F150 HydrophobicContact CE1-CE1 4.25Å; V120-F150 HydrophobicContact CB-CE1 4.45Å; V120-F150 HydrophobicContact CG1-CE1 3.85Å; V120-F150 HydrophobicContact CG1-CZ 3.6Å; V120-F150 HydrophobicContact CG2-CD1 4.18Å; V120-F150 HydrophobicContact CG2-CE1 3.65Å; V120-F150 HydrophobicContact CG2-CZ 4.21Å; D128-F150 VanDerWaalsContact O-CE2 3.27Å; D128-F150 WeakPolarHBondContact O-CE2 3.43Å; D128-F150 VanDerWaalsContact OD1-CE2 3.24Å; D128-F150 WeakPolarHBondContact OD1-CE2 3.41Å; A132-F150 HydrophobicContact CB-CD2 3.86Å; A132-F150 HydrophobicContact CB-CE2 3.84Å; A132-F150 HydrophobicContact CB-CZ 4.47Å; F150-G152 PolarHBondContact O-N 3.14Å; F150-V153 PolarHBondContact N-O 3.48Å; F150-V153 PolarHBondContact O-N 3.42Å; F150-Y155 HydrophobicContact CB-CD2 3.79Å; F150-Y155 HydrophobicContact CB-CE2 3.9Å; F150-Y155 HydrophobicContact CD1-CE2 4.11Å
151Q90.5Very high85.9Confident95 Ų9538.9 Ų38.944%0.44422%0.22SC..THydrogen-bonded Turntrans47.836.8-178.5-56.4-169.410.500114.8K124 D128K124-Q151 VanDerWaalsContact NZ-CD 3.34Å; D128-Q151 VanDerWaalsContact CG-NE2 3.34Å; D128-Q151 VanDerWaalsContact OD1-CG 3.24Å; D128-Q151 WeakPolarHBondContact OD1-CG 3.45Å; D128-Q151 PolarHBondContact OD1-NE2 3.26Å; D128-Q151 PolarHBondContact OD2-NE2 3.06Å
152G89.4Confident86.6Confident65 Ų6535.2 Ų35.267%0.6721%0.205SC*.THydrogen-bonded Turntrans87.43.6177.100000115.9F150F150-G152 PolarHBondContact O-N 3.14Å
153V92Very high87.5Confident57 Ų5734.7 Ų34.735%0.34520%0.204SC..EExtended strand (participates in β ladder)trans-117.2140.6177.6176.40000110R111 M149 F150 Y155R111-V153 HydrophobicContact CG-CG1 3.95Å; M149-V153 CarbonylContact C-O 3.4Å; M149-V153 VanDerWaalsContact CA-O 3.27Å; M149-V153 WeakPolarHBondContact CA-O 3.37Å; F150-V153 PolarHBondContact N-O 3.48Å; F150-V153 PolarHBondContact O-N 3.42Å; V153-Y155 HydrophobicContact CB-CD2 4.42Å; V153-Y155 HydrophobicContact CB-CE2 3.64Å; V153-Y155 HydrophobicContact CG1-CD2 4.35Å; V153-Y155 HydrophobicContact CG1-CE1 4.45Å; V153-Y155 HydrophobicContact CG1-CE2 3.72Å; V153-Y155 WeakPolarHBondContact O-CD2 3.48Å; V153-Y155 WeakPolarHBondContact O-CE2 3.15Å
154H92.1Very high88.3Confident54 Ų5435.1 Ų35.125%0.2521%0.206CC..EExtended strand (participates in β ladder)trans-78132.8175.2-73.6-69.5000112.2L112 P147 P148 M149L112-H154 HydrophobicContact CB-CB 4.13Å; L112-H154 WeakPolarHBondContact CB-O 3.42Å; L112-H154 HydrophobicContact CD2-CB 3.93Å; L112-H154 PolarHBondContact N-O 3.42Å; L112-H154 VanDerWaalsContact N-O 3.1Å; P147-H154 HydrophobicContact CG-CB 4.36Å; P147-H154 PolarHBondContact O-CE1 2.86Å; P147-H154 PolarHBondContact O-ND1 2.93Å; P148-H154 PolarHBondContact O-ND1 2.88Å; M149-H154 WeakPolarHBondContact CG-CE1 3.24Å; M149-H154 WeakPolarHBondContact CG-ND1 3.48Å
155Y93.5Very high89.1Confident12 Ų1234.1 Ų34.15%0.04720%0.195CC..EExtended strand (participates in β ladder)trans-130.7158.5176.7-64.5-89.7000111L109 T110 R111 F118 P148 F150 V153L109-Y155 HydrophobicContact CB-CD1 3.61Å; L109-Y155 HydrophobicContact CB-CE1 4.23Å; L109-Y155 HydrophobicContact CB-CG 4.09Å; L109-Y155 HydrophobicContact CD1-CD1 4.02Å; L109-Y155 HydrophobicContact CD1-CD2 4.12Å; L109-Y155 HydrophobicContact CD1-CE1 4.34Å; L109-Y155 HydrophobicContact CD1-CE2 4.42Å; L109-Y155 HydrophobicContact CD1-CG 3.93Å; L109-Y155 HydrophobicContact CG-CD1 4.46Å; T110-Y155 CarbonylContact O-C 3.4Å; T110-Y155 VanDerWaalsContact O-CA 3.32Å; T110-Y155 WeakPolarHBondContact O-CA 3.5Å; R111-Y155 HydrophobicContact CB-CD1 3.95Å; R111-Y155 HydrophobicContact CB-CE1 3.73Å; R111-Y155 HydrophobicContact CG-CD1 4.44Å; R111-Y155 HydrophobicContact CG-CE1 4.05Å; F118-Y155 HydrophobicContact CB-CE1 3.87Å; F118-Y155 AromaticContact CD1-CE1 3.9Å; F118-Y155 HydrophobicContact CD1-CE1 3.9Å; F118-Y155 AromaticContact CD1-CZ 3.84Å; F118-Y155 WeakPolarHBondContact CD1-OH 3.32Å; F118-Y155 HydrophobicContact CG-CE1 4.22Å; P148-Y155 PolarHBondContact O-N 3.29Å; F150-Y155 HydrophobicContact CB-CD2 3.79Å; F150-Y155 HydrophobicContact CB-CE2 3.9Å; F150-Y155 HydrophobicContact CD1-CE2 4.11Å; V153-Y155 HydrophobicContact CB-CD2 4.42Å; V153-Y155 HydrophobicContact CB-CE2 3.64Å; V153-Y155 HydrophobicContact CG1-CD2 4.35Å; V153-Y155 HydrophobicContact CG1-CE1 4.45Å; V153-Y155 HydrophobicContact CG1-CE2 3.72Å; V153-Y155 WeakPolarHBondContact O-CD2 3.48Å; V153-Y155 WeakPolarHBondContact O-CE2 3.15Å
156I92Very high90Very high0 Ų035.1 Ų35.10%020%0.201CC..EExtended strand (participates in β ladder)trans-126.7175.9171.571.8176.5000109.4T110 L112 C135 F138 P140 P147 G158 W160 F402T110-I156 HydrophobicContact CG2-CD1 4.29Å; T110-I156 HydrophobicContact CG2-CG1 3.99Å; T110-I156 PolarHBondContact N-O 3.23Å; T110-I156 PolarHBondContact O-N 3.19Å; L112-I156 HydrophobicContact CD1-CG2 4.04Å; C135-I156 CarbonylContact O-C 3.55Å; C135-I156 VanDerWaalsContact O-C 3.25Å; F138-I156 HydrophobicContact CD1-CB 4.34Å; F138-I156 HydrophobicContact CD1-CG2 4.04Å; F138-I156 HydrophobicContact CE1-CG2 4.48Å; P140-I156 HydrophobicContact CG-CB 4.21Å; P140-I156 HydrophobicContact CG-CD1 4.21Å; P140-I156 HydrophobicContact CG-CG2 3.96Å; P147-I156 HydrophobicContact CB-CG2 4.36Å; I156-G158 PolarHBondContact O-N 2.64Å; I156-W160 HydrophobicContact CD1-CB 4.32Å; I156-W160 HydrophobicContact CD1-CD2 4.34Å; I156-W160 HydrophobicContact CD1-CG 3.97Å; I156-F402 HydrophobicContact CD1-CD1 3.86Å; I156-F402 HydrophobicContact CD1-CE1 3.36Å; I156-F402 HydrophobicContact CD1-CZ 3.95Å
157D92.4Very high90.3Very high10 Ų1034.3 Ų34.35%0.05320%0.195CC..EExtended strand (participates in β ladder)trans-46.8133.6-176.2-172.8-51.9000112.9S38 T110 C135 S136 F138 I139 G159 W160S38-D157 WeakPolarHBondContact CB-OD2 3.48Å; S38-D157 PolarHBondContact OG-OD2 2.92Å; T110-D157 WeakPolarHBondContact CB-O 3.48Å; T110-D157 PolarHBondContact OG1-O 2.96Å; C135-D157 PolarHBondContact O-N 2.79Å; S136-D157 VanDerWaalsContact O-CA 3.23Å; S136-D157 WeakPolarHBondContact O-CA 3.3Å; S136-D157 WeakPolarHBondContact O-CB 3.36Å; F138-D157 WeakPolarHBondContact O-CB 3.43Å; F138-D157 PolarHBondContact O-N 2.99Å; I139-D157 HydrophobicContact CG1-CB 4.12Å; D157-G159 PolarHBondContact O-N 3.32Å; D157-G159 PolarHBondContact OD1-N 3.15Å; D157-W160 PolarHBondContact O-N 3.34Å
158G90.1Very high90.3Very high0 Ų037.1 Ų37.10%021%0.209CC..G310 helixtrans-58.3-31.7-176.500000113.4S108 T110 S136 I156 W160 S161 D162S108-G158 VanDerWaalsContact O-CA 3.29Å; S108-G158 WeakPolarHBondContact O-CA 3.3Å; S108-G158 WeakPolarHBondContact OG-CA 3.46Å; S108-G158 PolarHBondContact OG-O 3.28Å; T110-G158 PolarHBondContact OG1-O 3.34Å; S136-G158 PolarHBondContact O-N 3.14Å; I156-G158 PolarHBondContact O-N 2.64Å; G158-W160 PolarHBondContact O-N 3.3Å; G158-S161 PolarHBondContact O-N 3.44Å; G158-S161 PolarHBondContact O-OG 3.25Å; G158-D162 CarbonylContact C-O 3.52Å; G158-D162 CarbonylContact O-C 3.58Å; G158-D162 PolarHBondContact O-N 2.75Å
159G88.4Confident90Very high12 Ų1246.5 Ų46.512%0.12425%0.248CC..G310 helixtrans-63.6-11.7-178.400000115.5D157 S161 N163D157-G159 PolarHBondContact O-N 3.32Å; D157-G159 PolarHBondContact OD1-N 3.15Å; G159-S161 VanDerWaalsContact C-N 3.3Å; G159-N163 WeakPolarHBondContact CA-OD1 3.49Å
160W85.4Confident89.6Confident89 Ų8948.7 Ų48.734%0.33726%0.257SS..G310 helixtrans-73.9-18.7170.1-72.484.6000113.6T110 I156 D157 G158 K199 F402 L403T110-W160 HydrophobicContact CG2-CB 3.95Å; I156-W160 HydrophobicContact CD1-CB 4.32Å; I156-W160 HydrophobicContact CD1-CD2 4.34Å; I156-W160 HydrophobicContact CD1-CG 3.97Å; D157-W160 PolarHBondContact O-N 3.34Å; G158-W160 PolarHBondContact O-N 3.3Å; W160-K199 VanDerWaalsContact O-CE 3.25Å; W160-K199 WeakPolarHBondContact O-CE 3.45Å; W160-K199 PolarHBondContact O-NZ 2.68Å; W160-F402 HydrophobicContact CE3-CE1 4.27Å; W160-L403 HydrophobicContact CE3-CD2 4.38Å; W160-L403 HydrophobicContact CH2-CD2 3.36Å; W160-L403 HydrophobicContact CZ2-CD2 4.07Å; W160-L403 HydrophobicContact CZ3-CD2 3.55Å
161S88.8Confident89.4Confident24 Ų2448.9 Ų48.917%0.16826%0.258CS..THydrogen-bonded Turntrans-125.6-45.4-177.957.10000113.2T110 N117 G158 G159T110-S161 WeakPolarHBondContact OG1-CB 3.44Å; T110-S161 PolarHBondContact OG1-N 2.75Å; T110-S161 PolarHBondContact OG1-OG 3.13Å; N117-S161 WeakPolarHBondContact CA-OG 3.3Å; N117-S161 WeakPolarHBondContact CB-OG 3.29Å; N117-S161 PolarHBondContact ND2-OG 2.98Å; G158-S161 PolarHBondContact O-N 3.44Å; G158-S161 PolarHBondContact O-OG 3.25Å; G159-S161 VanDerWaalsContact C-N 3.3Å
162D90.6Very high89.4Confident30 Ų3045 Ų4516%0.1624%0.24CC..  trans-147.9111170.2-174.9-10.2000109.6S108 G158 L164 P165 N200S108-D162 WeakPolarHBondContact CB-O 3.26Å; S108-D162 PolarHBondContact OG-O 2.77Å; G158-D162 CarbonylContact C-O 3.52Å; G158-D162 CarbonylContact O-C 3.58Å; G158-D162 PolarHBondContact O-N 2.75Å; D162-L164 PolarHBondContact OD1-N 2.9Å; D162-P165 WeakPolarHBondContact OD1-CA 3.42Å; D162-P165 VanDerWaalsContact OD2-CA 3.28Å; D162-P165 WeakPolarHBondContact OD2-CA 3.46Å; D162-N200 WeakPolarHBondContact OD1-CB 3.48Å
163N91.6Very high89.6Confident11 Ų1142.8 Ų42.86%0.05921%0.214CC..SBendtrans-88.6-15.4-175.1-172.171.5000113.5S6 G7 G159 L198 K199 T201S6-N163 CarbonylContact C-O 3.23Å; S6-N163 WeakPolarHBondContact CA-O 3.49Å; G7-N163 WeakPolarHBondContact CA-OD1 3.23Å; G7-N163 PolarHBondContact N-O 3.44Å; G7-N163 PolarHBondContact N-OD1 2.81Å; G7-N163 PolarHBondContact O-ND2 2.9Å; G159-N163 WeakPolarHBondContact CA-OD1 3.49Å; N163-L198 WeakPolarHBondContact CB-O 3.25Å; N163-K199 HydrophobicContact CB-CB 4.39Å; N163-K199 WeakPolarHBondContact CB-O 3.25Å; N163-K199 PolarHBondContact N-O 2.79Å; N163-T201 WeakPolarHBondContact CB-OG1 3.38Å; N163-T201 PolarHBondContact ND2-OG1 3.28Å
164L91.2Very high89.7Confident10 Ų1040 Ų405%0.05220%0.197CC..SBendtrans-145.771.4-178.7178.565.9000108.8S4 D162 V166 T173 A181 N200 T201S4-L164 WeakPolarHBondContact OG-CD1 3.4Å; D162-L164 PolarHBondContact OD1-N 2.9Å; L164-V166 PolarHBondContact O-N 3.37Å; L164-V166 VanDerWaalsContact O-N 3.14Å; L164-T173 HydrophobicContact CD2-CG2 4.31Å; L164-T173 HydrophobicContact CG-CG2 4.43Å; L164-A181 HydrophobicContact CD2-CB 4.48Å; L164-N200 WeakPolarHBondContact CB-O 3.43Å; L164-N200 PolarHBondContact O-ND2 3.46Å; L164-T201 VanDerWaalsContact CB-OG1 3.3Å; L164-T201 WeakPolarHBondContact CB-OG1 3.42Å
165P91.6Very high89.8Confident2 Ų237.5 Ų37.51%0.01319%0.186CC..  trans-65.1113.4-172.324.8-36.8000112.2S4 S35 L119 D162S4-P165 VanDerWaalsContact CB-O 3.29Å; S4-P165 WeakPolarHBondContact CB-O 3.34Å; S4-P165 PolarHBondContact OG-O 3.01Å; S35-P165 WeakPolarHBondContact CB-O 3.28Å; S35-P165 PolarHBondContact OG-O 3.46Å; L119-P165 HydrophobicContact CD1-CB 3.77Å; L119-P165 HydrophobicContact CD1-CG 4.1Å; D162-P165 WeakPolarHBondContact OD1-CA 3.42Å; D162-P165 VanDerWaalsContact OD2-CA 3.28Å; D162-P165 WeakPolarHBondContact OD2-CA 3.46Å
166V90.6Very high89.7Confident70 Ų7037.1 Ų37.142%0.42418%0.184SC..  trans-90127.7179.9-179.70000109.7L164 D168 T173L164-V166 PolarHBondContact O-N 3.37Å; L164-V166 VanDerWaalsContact O-N 3.14Å; V166-D168 VanDerWaalsContact CG1-O 3.3Å; V166-D168 WeakPolarHBondContact CG1-O 3.46Å; V166-T173 HydrophobicContact CG2-CG2 4.09Å
167L88.1Confident89.6Confident45 Ų4537.5 Ų37.524%0.23619%0.186CC..  trans-89.6-35.2-175.6-59.5179.8000113.1K33 F106 L119K33-L167 HydrophobicContact CB-CD1 3.55Å; K33-L167 HydrophobicContact CD-CD1 4.28Å; F106-L167 HydrophobicContact CB-CD2 3.97Å; F106-L167 HydrophobicContact CD1-CD2 3.85Å; F106-L167 HydrophobicContact CD2-CD1 3.87Å; F106-L167 HydrophobicContact CD2-CD2 4.32Å; F106-L167 HydrophobicContact CE1-CD2 4.46Å; F106-L167 HydrophobicContact CE2-CD1 4.33Å; F106-L167 HydrophobicContact CG-CD1 4.15Å; F106-L167 HydrophobicContact CG-CD2 3.78Å; L119-L167 HydrophobicContact CD2-CD2 3.89Å
168D86.2Confident89.3Confident61 Ų6137.2 Ų37.233%0.32619%0.185SC..SBendtrans-161177.3179.353.245.1000110.9N2 V166 E170 T171N2-D168 PolarHBondContact ND2-OD2 2.91Å; V166-D168 VanDerWaalsContact CG1-O 3.3Å; V166-D168 WeakPolarHBondContact CG1-O 3.46Å; D168-E170 PolarHBondContact O-N 3.37Å; D168-E170 VanDerWaalsContact OD1-C 3.27Å; D168-E170 WeakPolarHBondContact OD1-CA 3.48Å; D168-E170 PolarHBondContact OD1-N 3.5Å; D168-T171 PolarHBondContact N-OG1 2.58Å; D168-T171 VanDerWaalsContact N-OG1 3.12Å; D168-T171 WeakPolarHBondContact O-CB 3.09Å; D168-T171 PolarHBondContact O-N 3.41Å; D168-T171 PolarHBondContact O-OG1 2.96Å; D168-T171 PolarHBondContact OD1-N 3.46Å; D168-T171 PolarHBondContact OD1-OG1 3.04Å
169K83.4Confident89Confident221 Ų22137.7 Ų37.796%0.96119%0.19SC*.THydrogen-bonded Turntrans-69.6-4178.7-63.7-175.1177.6-176.20114.5
170E82.3Confident88.7Confident150 Ų15040.2 Ų40.270%0.70120%0.198SC*.THydrogen-bonded Turntrans-113.210.8178.8-59.1-172173.200112.1D168 I172D168-E170 PolarHBondContact O-N 3.37Å; D168-E170 VanDerWaalsContact OD1-C 3.27Å; D168-E170 WeakPolarHBondContact OD1-CA 3.48Å; D168-E170 PolarHBondContact OD1-N 3.5Å; E170-I172 PolarHBondContact O-N 3.5Å
171T88Confident88.8Confident9 Ų936.6 Ų36.66%0.05519%0.188CC..EExtended strand (participates in β ladder)trans-82.8110-180-64.80000110N2 D168 T173N2-T171 HydrophobicContact CB-CG2 4.46Å; N2-T171 WeakPolarHBondContact O-CA 3.39Å; D168-T171 PolarHBondContact N-OG1 2.58Å; D168-T171 VanDerWaalsContact N-OG1 3.12Å; D168-T171 WeakPolarHBondContact O-CB 3.09Å; D168-T171 PolarHBondContact O-N 3.41Å; D168-T171 PolarHBondContact O-OG1 2.96Å; D168-T171 PolarHBondContact OD1-N 3.46Å; D168-T171 PolarHBondContact OD1-OG1 3.04Å; T171-T173 PolarHBondContact O-N 3.05Å
172I90.7Very high88.8Confident13 Ų1339.3 Ų39.37%0.06720%0.2CC..EExtended strand (participates in β ladder)trans-69.8121.4178.8-59.8164.1000109.3M1 N2 F3 S4 E170 D182 I183 F239M1-I172 HydrophobicContact SD-CD1 4.31Å; N2-I172 PolarHBondContact O-N 3.44Å; F3-I172 CarbonylContact C-O 3.56Å; F3-I172 VanDerWaalsContact CA-O 3.28Å; F3-I172 WeakPolarHBondContact CA-O 3.45Å; F3-I172 HydrophobicContact CD1-CB 3.71Å; F3-I172 HydrophobicContact CD1-CG2 3.9Å; F3-I172 HydrophobicContact CE1-CB 3.77Å; F3-I172 HydrophobicContact CE1-CD1 3.96Å; F3-I172 HydrophobicContact CE1-CG1 4.48Å; F3-I172 HydrophobicContact CE1-CG2 3.66Å; F3-I172 HydrophobicContact CE2-CD1 4.31Å; F3-I172 HydrophobicContact CG-CB 4.36Å; F3-I172 HydrophobicContact CZ-CB 4.46Å; F3-I172 HydrophobicContact CZ-CD1 3.82Å; S4-I172 PolarHBondContact N-O 3.19Å; E170-I172 PolarHBondContact O-N 3.5Å; I172-D182 HydrophobicContact CG2-CB 3.99Å; I172-I183 HydrophobicContact CG2-CD1 3.99Å; I172-I183 HydrophobicContact CG2-CG1 4.18Å; I172-F239 HydrophobicContact CD1-CE1 4Å; I172-F239 HydrophobicContact CD1-CZ 4.06Å; I172-F239 HydrophobicContact CG1-CE1 4.43Å; I172-F239 HydrophobicContact CG1-CZ 4.04Å; I172-F239 HydrophobicContact CG2-CE1 3.88Å; I172-F239 HydrophobicContact CG2-CE2 4.28Å; I172-F239 HydrophobicContact CG2-CZ 3.67Å
173T92.8Very high88.8Confident18 Ų1838 Ų3811%0.1119%0.193CC..EExtended strand (participates in β ladder)trans-92.6138.3-175.658.50000112.8L164 V166 T171 A181 D182 I183L164-T173 HydrophobicContact CD2-CG2 4.31Å; L164-T173 HydrophobicContact CG-CG2 4.43Å; V166-T173 HydrophobicContact CG2-CG2 4.09Å; T171-T173 PolarHBondContact O-N 3.05Å; T173-A181 VanDerWaalsContact OG1-CA 3.28Å; T173-A181 WeakPolarHBondContact OG1-CA 3.39Å; T173-D182 WeakPolarHBondContact CB-OD2 3.5Å; T173-D182 PolarHBondContact N-OD2 3.48Å; T173-D182 WeakPolarHBondContact O-CB 3.49Å; T173-D182 PolarHBondContact O-N 3.42Å; T173-D182 PolarHBondContact OG1-N 3.15Å; T173-D182 PolarHBondContact OG1-OD2 2.81Å; T173-I183 PolarHBondContact O-N 3.25Å
174V94.3Very high88.8Confident0 Ų038.5 Ų38.50%020%0.197CC..EExtended strand (participates in β ladder)trans-128.5119.3-175.7-171.40000110.1F3 S4 F5 S6 Y14 V18 I183F3-V174 HydrophobicContact CD1-CG2 4.15Å; S4-V174 WeakPolarHBondContact O-CB 3.33Å; S4-V174 PolarHBondContact O-N 2.71Å; F5-V174 HydrophobicContact CD1-CB 3.92Å; F5-V174 HydrophobicContact CD1-CG1 3.91Å; F5-V174 HydrophobicContact CD1-CG2 4.24Å; F5-V174 HydrophobicContact CD2-CG2 4.42Å; F5-V174 HydrophobicContact CE1-CB 4.09Å; F5-V174 HydrophobicContact CE1-CG1 3.88Å; F5-V174 HydrophobicContact CE1-CG2 4.01Å; F5-V174 HydrophobicContact CE2-CG2 4.18Å; F5-V174 HydrophobicContact CG-CB 4.23Å; F5-V174 HydrophobicContact CG-CG2 4.44Å; F5-V174 HydrophobicContact CZ-CG2 3.97Å; S6-V174 PolarHBondContact N-O 3.17Å; Y14-V174 HydrophobicContact CE1-CG1 4.23Å; V18-V174 HydrophobicContact CB-CG1 4.23Å; V18-V174 HydrophobicContact CG1-CG1 3.86Å; V18-V174 HydrophobicContact CG1-CG2 4.25Å; V18-V174 HydrophobicContact CG2-CG1 3.76Å; V174-I183 HydrophobicContact CG1-CB 4.3Å; V174-I183 HydrophobicContact CG1-CG2 4.32Å; V174-I183 HydrophobicContact CG2-CB 4.26Å; V174-I183 HydrophobicContact CG2-CD1 4.26Å
175S93.8Very high88.7Confident1 Ų138 Ų381%0.00720%0.195CC..  trans-133.9133.9179.1172.50000110.4Y14 F177 I183 C184 P185Y14-S175 WeakPolarHBondContact CE1-O 3.42Å; S175-F177 PolarHBondContact O-N 3.43Å; S175-F177 PolarHBondContact OG-N 2.97Å; S175-F177 PolarHBondContact OG-O 3.47Å; S175-I183 PolarHBondContact N-O 3.48Å; S175-C184 VanDerWaalsContact O-CA 3.27Å; S175-C184 WeakPolarHBondContact O-CA 3.47Å; S175-C184 VanDerWaalsContact O-CB 3.32Å; S175-C184 WeakPolarHBondContact O-CB 3.43Å; S175-P185 WeakPolarHBondContact O-CD 3.34Å
176P91.9Very high88.1Confident3 Ų341.1 Ų41.12%0.01922%0.221CC..SBendtrans-78.3-2.3170.834.8-32000112.4S6 C8 L11 Y14 P185 R212S6-P176 WeakPolarHBondContact OG-CD 3.24Å; C8-P176 HydrophobicContact CB-CG 3.55Å; L11-P176 HydrophobicContact CB-CB 4.15Å; L11-P176 HydrophobicContact CB-CG 4.1Å; L11-P176 HydrophobicContact CD1-CB 4.22Å; L11-P176 HydrophobicContact CD1-CG 4.32Å; Y14-P176 HydrophobicContact CD1-CB 3.63Å; Y14-P176 HydrophobicContact CD2-CB 4.32Å; Y14-P176 HydrophobicContact CE1-CB 4.23Å; Y14-P176 HydrophobicContact CG-CB 3.69Å; P176-P185 WeakPolarHBondContact O-CG 3.47Å; P176-R212 VanDerWaalsContact O-CD 3.25Å; P176-R212 WeakPolarHBondContact O-CD 3.27Å; P176-R212 PolarHBondContact O-NE 2.9Å
177F89.8Confident87.2Confident8 Ų839 Ų394%0.03521%0.207CC..SBendtrans-103.9135.5175.1-49.2-78.9000110L11 S175 G179 C184 I203 R212 I213 A216L11-F177 HydrophobicContact CD1-CE1 3.93Å; L11-F177 HydrophobicContact CD1-CZ 4.24Å; S175-F177 PolarHBondContact O-N 3.43Å; S175-F177 PolarHBondContact OG-N 2.97Å; S175-F177 PolarHBondContact OG-O 3.47Å; F177-G179 PolarHBondContact O-N 3.04Å; F177-C184 WeakPolarHBondContact O-CB 3.34Å; F177-I203 HydrophobicContact CB-CD1 4.06Å; F177-I203 HydrophobicContact CB-CG1 3.93Å; F177-I203 HydrophobicContact CB-CG2 3.99Å; F177-I203 HydrophobicContact CD1-CD1 4.42Å; F177-I203 HydrophobicContact CD2-CD1 3.87Å; F177-I203 HydrophobicContact CD2-CG1 4.47Å; F177-I203 HydrophobicContact CE2-CD1 4.42Å; F177-I203 HydrophobicContact CG-CD1 3.87Å; F177-I203 HydrophobicContact CG-CG1 4.3Å; F177-R212 HydrophobicContact CD1-CB 3.73Å; F177-R212 HydrophobicContact CE1-CB 3.88Å; F177-I213 HydrophobicContact CD1-CG1 4.17Å; F177-I213 HydrophobicContact CE1-CG1 3.7Å; F177-I213 HydrophobicContact CZ-CG1 4.46Å; F177-A216 HydrophobicContact CZ-CB 4.35Å
178S86.8Confident85.6Confident5 Ų541.6 Ų41.64%0.03524%0.235CC..SBendtrans-65.1130.1177.2-165.70000110.5P185 D187 R204 N209S178-P185 WeakPolarHBondContact CB-O 3.16Å; S178-P185 PolarHBondContact OG-O 2.95Å; S178-D187 WeakPolarHBondContact CB-OD2 3.42Å; S178-R204 PolarHBondContact O-N 2.94Å; S178-N209 PolarHBondContact N-ND2 3.14Å; S178-N209 PolarHBondContact N-OD1 3.27Å; S178-N209 PolarHBondContact O-ND2 2.89Å
179G82.6Confident83.9Confident9 Ų944.6 Ų44.69%0.09325%0.247CC..BIsolated β-bridgetrans-164.4-137.1-165.900000113.1F177 T202 R204F177-G179 PolarHBondContact O-N 3.04Å; G179-T202 WeakPolarHBondContact CA-O 3.2Å; G179-R204 PolarHBondContact O-NH1 3.12Å; G179-R204 PolarHBondContact O-NH2 3.44Å
180E82Confident81.8Confident65 Ų6538.5 Ų38.530%0.30423%0.232SC..SBendtrans-110.53.2170.6-54.6169.1149.600112.1L195 T202 Q421E180-L195 HydrophobicContact CG-CD2 3.58Å; E180-T202 WeakPolarHBondContact CB-OG1 3.41Å; E180-T202 WeakPolarHBondContact CG-OG1 3.37Å; E180-T202 VanDerWaalsContact OE2-CB 3.23Å; E180-T202 WeakPolarHBondContact OE2-CB 3.33Å; E180-T202 VanDerWaalsContact OE2-CG2 3.26Å; E180-T202 WeakPolarHBondContact OE2-CG2 3.27Å; E180-T202 PolarHBondContact OE2-OG1 2.87Å; E180-Q421 PolarHBondContact OE1-OE1 3.33Å
181A87.3Confident79.9Confident14 Ų1434 Ų3412%0.11623%0.225CC..  trans-73.4140.9179.600000112.8L164 T173 I183 C184L164-A181 HydrophobicContact CD2-CB 4.48Å; T173-A181 VanDerWaalsContact OG1-CA 3.28Å; T173-A181 WeakPolarHBondContact OG1-CA 3.39Å; A181-I183 VanDerWaalsContact C-N 3.3Å; A181-I183 PolarHBondContact O-N 3.23Å; A181-C184 HydrophobicContact CB-CB 4.35Å; A181-C184 PolarHBondContact O-SG 3.5Å
182D88.9Confident78Confident80 Ų8033.8 Ų33.843%0.42823%0.225SC..SBendtrans-53.9-42.8-173.5-60.8-84.4000113.3I172 T173 F239I172-D182 HydrophobicContact CG2-CB 3.99Å; T173-D182 WeakPolarHBondContact CB-OD2 3.5Å; T173-D182 PolarHBondContact N-OD2 3.48Å; T173-D182 WeakPolarHBondContact O-CB 3.49Å; T173-D182 PolarHBondContact O-N 3.42Å; T173-D182 PolarHBondContact OG1-N 3.15Å; T173-D182 PolarHBondContact OG1-OD2 2.81Å; D182-F239 HydrophobicContact CB-CD2 4.06Å; D182-F239 HydrophobicContact CB-CE2 3.66Å; D182-F239 HydrophobicContact CB-CZ 4.41Å; D182-F239 WeakPolarHBondContact O-CD2 3.29Å
183I90.4Very high76.1Confident2 Ų238.8 Ų38.81%0.0125%0.246CC..BIsolated β-bridgetrans-116.190.1176.4-54.1-178.9000108.6F3 Y14 V18 I172 T173 V174 S175 A181 D235 T236 F239F3-I183 HydrophobicContact CE1-CD1 4.39Å; Y14-I183 PolarHBondContact OH-O 2.7Å; V18-I183 HydrophobicContact CG1-CD1 4.42Å; V18-I183 HydrophobicContact CG1-CG2 4.45Å; V18-I183 HydrophobicContact CG2-CG2 4.06Å; I172-I183 HydrophobicContact CG2-CD1 3.99Å; I172-I183 HydrophobicContact CG2-CG1 4.18Å; T173-I183 PolarHBondContact O-N 3.25Å; V174-I183 HydrophobicContact CG1-CB 4.3Å; V174-I183 HydrophobicContact CG1-CG2 4.32Å; V174-I183 HydrophobicContact CG2-CB 4.26Å; V174-I183 HydrophobicContact CG2-CD1 4.26Å; S175-I183 PolarHBondContact N-O 3.48Å; A181-I183 VanDerWaalsContact C-N 3.3Å; A181-I183 PolarHBondContact O-N 3.23Å; I183-D235 HydrophobicContact CG2-CB 4.49Å; I183-T236 HydrophobicContact CD1-CG2 4.19Å; I183-T236 WeakPolarHBondContact CG2-OG1 3.3Å; I183-F239 HydrophobicContact CD1-CB 4.35Å; I183-F239 HydrophobicContact CD1-CD1 3.81Å; I183-F239 HydrophobicContact CD1-CE1 4.35Å; I183-F239 HydrophobicContact CD1-CG 4.06Å; I183-F239 HydrophobicContact CG1-CB 3.87Å; I183-F239 HydrophobicContact CG1-CD1 3.94Å; I183-F239 HydrophobicContact CG1-CD2 4.02Å; I183-F239 HydrophobicContact CG1-CG 3.66Å
184C91.3Very high74.3Confident22 Ų2241 Ų4115%0.14926%0.257CS..  trans-140.4163.4172.372.10000113.2Y14 S175 F177 A181 A186Y14-C184 WeakPolarHBondContact OH-CA 3.34Å; S175-C184 VanDerWaalsContact O-CA 3.27Å; S175-C184 WeakPolarHBondContact O-CA 3.47Å; S175-C184 VanDerWaalsContact O-CB 3.32Å; S175-C184 WeakPolarHBondContact O-CB 3.43Å; F177-C184 WeakPolarHBondContact O-CB 3.34Å; A181-C184 HydrophobicContact CB-CB 4.35Å; A181-C184 PolarHBondContact O-SG 3.5Å; C184-A186 PolarHBondContact O-N 3.15Å
185P89.2Confident72.9Confident0 Ų041.8 Ų41.80%026%0.261CS..  trans-61.1131.2177.3-27.236.9000113.6Y14 S175 P176 S178 D187 Q231 D235Y14-P185 HydrophobicContact CE2-CG 3.77Å; S175-P185 WeakPolarHBondContact O-CD 3.34Å; P176-P185 WeakPolarHBondContact O-CG 3.47Å; S178-P185 WeakPolarHBondContact CB-O 3.16Å; S178-P185 PolarHBondContact OG-O 2.95Å; P185-D187 PolarHBondContact O-N 3.16Å; P185-Q231 HydrophobicContact CG-CG 4.49Å; P185-D235 WeakPolarHBondContact CA-OD2 3.42Å
186A79.9Confident71.7Confident68 Ų6845 Ų4556%0.56228%0.275SS*.  trans-79.195.3172.100000111.1C184 A188C184-A186 PolarHBondContact O-N 3.15Å; A186-A188 PolarHBondContact O-N 2.97Å
187D71.2Confident70.7Confident26 Ų2649.7 Ų49.714%0.13930%0.3CS..  trans-77.186.4173-78.8-9.7000110.7S178 P185 E189 T206 K208 R212S178-D187 WeakPolarHBondContact CB-OD2 3.42Å; P185-D187 PolarHBondContact O-N 3.16Å; D187-E189 PolarHBondContact O-N 3.09Å; D187-T206 HydrophobicContact CB-CG2 4.34Å; D187-T206 PolarHBondContact OD2-OG1 3.5Å; D187-K208 HydrophobicContact CB-CD 4.38Å; D187-K208 VanDerWaalsContact OD1-CD 3.27Å; D187-K208 WeakPolarHBondContact OD1-CD 3.42Å; D187-K208 WeakPolarHBondContact OD2-CB 3.35Å; D187-R212 IonicContact OD1-CZ 3.89Å; D187-R212 VanDerWaalsContact OD1-CZ 3.29Å; D187-R212 IonicContact OD1-NH1 3.27Å; D187-R212 PolarHBondContact OD1-NH1 3.28Å; D187-R212 IonicContact OD1-NH2 3.15Å; D187-R212 PolarHBondContact OD1-NH2 2.98Å; D187-R212 IonicContact OD2-CZ 2.71Å; D187-R212 IonicContact OD2-NH1 2.69Å; D187-R212 PolarHBondContact OD2-NH1 3.35Å
188A54.1Low69.8Low99 Ų9953 Ų5382%0.81832%0.318SS*.  trans-71.317-178.900000115.6A186A186-A188 PolarHBondContact O-N 2.97Å
189E50.4Low69.3Low124 Ų12456.2 Ų56.258%0.57933%0.331SS*.SBendtrans-131130.5-176.3-73.8179.7130.100111.8D187 K208D187-E189 PolarHBondContact O-N 3.09Å; E189-K208 WeakPolarHBondContact OE2-CE 3.34Å; E189-K208 IonicContact OE2-NZ 2.68Å; E189-K208 PolarHBondContact OE2-NZ 3.06Å
190S40.5Very low69.1Low93 Ų9359.6 Ų59.665%0.6535%0.347SS*.  trans71.4127.1176.1-47.20000115.7S192S190-S192 PolarHBondContact O-N 3.3Å
191G41Very low69Low54 Ų5456.6 Ų56.656%0.55733%0.333SS*.  trans-74.752.9-178.700000114F193G191-F193 WeakPolarHBondContact O-CD2 3.39Å; G191-F193 VanDerWaalsContact O-CE2 3.3Å; G191-F193 WeakPolarHBondContact O-CE2 3.48Å; G191-F193 PolarHBondContact O-N 3.3Å
192S48.7Very low68.7Low6 Ų657.8 Ų57.84%0.04234%0.339CS..  trans-71.694.4175.6178.50000110S190 L194 R204 F205S190-S192 PolarHBondContact O-N 3.3Å; S192-L194 PolarHBondContact O-N 3.2Å; S192-R204 WeakPolarHBondContact O-CD 3.32Å; S192-R204 WeakPolarHBondContact O-CG 3.46Å; S192-F205 WeakPolarHBondContact CB-O 3.31Å; S192-F205 PolarHBondContact OG-O 3.45Å
193F51.4Low68.2Low118 Ų11854 Ų5452%0.51832%0.319SS..  trans-742.6170.2-58.4-77.1000112.8G191G191-F193 WeakPolarHBondContact O-CD2 3.39Å; G191-F193 VanDerWaalsContact O-CE2 3.3Å; G191-F193 WeakPolarHBondContact O-CE2 3.48Å; G191-F193 PolarHBondContact O-N 3.3Å
194L55.3Low67.6Low64 Ų6456.7 Ų56.734%0.33533%0.329SS..  trans-91.4105.4-177.1-60.2178.6000109.9S192 F205 L418S192-L194 PolarHBondContact O-N 3.2Å; L194-F205 HydrophobicContact CB-CB 4.02Å; L194-F205 WeakPolarHBondContact O-CB 3.21Å; L194-F205 PolarHBondContact O-N 3.31Å; L194-L418 HydrophobicContact CD2-CD2 3.71Å
195L64.2Low66.5Low17 Ų1758.3 Ų58.39%0.08933%0.333CS..EExtended strand (participates in β ladder)trans-97.2146.5166.2-63.696.6000110.7E180 I203 M419E180-L195 HydrophobicContact CG-CD2 3.58Å; L195-I203 WeakPolarHBondContact CA-O 3.41Å; L195-M419 WeakPolarHBondContact CD1-O 3.41Å
196F68.4Low65.6Low68 Ų6858.7 Ų58.730%0.29834%0.336SS..EExtended strand (participates in β ladder)trans-122.9133.2165.863.5-86.3000109.8L198 I203 F205 I213F196-L198 HydrophobicContact CE2-CB 4.49Å; F196-L198 PolarHBondContact O-N 3.23Å; F196-I203 HydrophobicContact CD1-CB 4.4Å; F196-I203 WeakPolarHBondContact CD1-O 3.44Å; F196-I203 HydrophobicContact CD2-CB 4.29Å; F196-I203 HydrophobicContact CE1-CB 3.91Å; F196-I203 HydrophobicContact CE1-CG2 3.68Å; F196-I203 WeakPolarHBondContact CE1-O 3.28Å; F196-I203 HydrophobicContact CE2-CB 3.79Å; F196-I203 HydrophobicContact CE2-CD1 4.06Å; F196-I203 HydrophobicContact CE2-CG1 4.41Å; F196-I203 HydrophobicContact CE2-CG2 4.11Å; F196-I203 HydrophobicContact CZ-CB 3.58Å; F196-I203 HydrophobicContact CZ-CD1 4.31Å; F196-I203 HydrophobicContact CZ-CG2 3.4Å; F196-I203 VanDerWaalsContact CZ-CG2 3.4Å; F196-I203 PolarHBondContact N-O 2.72Å; F196-I203 PolarHBondContact O-N 2.84Å; F196-F205 HydrophobicContact CD1-CB 4.33Å; F196-F205 HydrophobicContact CD1-CD2 4.21Å; F196-F205 HydrophobicContact CE1-CB 4.45Å; F196-F205 HydrophobicContact CE1-CD2 4.03Å; F196-I213 HydrophobicContact CE2-CD1 4.44Å; F196-I213 HydrophobicContact CZ-CD1 3.88Å
197D71.5Confident65.1Low102 Ų10257 Ų5755%0.54532%0.32SS..EExtended strand (participates in β ladder)trans-83.8113.1174.317530.2000110.6K199 N200 T201 T202D197-K199 PolarHBondContact O-N 3.43Å; D197-K199 PolarHBondContact OD1-N 2.79Å; D197-N200 VanDerWaalsContact OD1-CA 3.3Å; D197-N200 WeakPolarHBondContact OD1-CA 3.49Å; D197-N200 PolarHBondContact OD1-N 3.49Å; D197-N200 PolarHBondContact OD2-N 2.88Å; D197-T201 PolarHBondContact OD1-N 2.94Å; D197-T202 HydrophobicContact CB-CG2 4.28Å
198L70.3Confident65.6Low77 Ų7758.9 Ų58.940%0.40333%0.327SS..SBendtrans-94.973168.3-170.969.4000109.6N163 F196 T201 I203N163-L198 WeakPolarHBondContact CB-O 3.25Å; F196-L198 HydrophobicContact CE2-CB 4.49Å; F196-L198 PolarHBondContact O-N 3.23Å; L198-T201 PolarHBondContact N-O 3.24Å; L198-T201 WeakPolarHBondContact O-CB 3.28Å; L198-I203 HydrophobicContact CB-CD1 3.99Å; L198-I203 HydrophobicContact CD2-CD1 3.93Å
199K77.4Confident67Low72 Ų7254.2 Ų54.231%0.31329%0.288SS..SBendtrans56.374.4175.5-63.7-72.2-176.8126.60112.5W160 N163 D197 T201W160-K199 VanDerWaalsContact O-CE 3.25Å; W160-K199 WeakPolarHBondContact O-CE 3.45Å; W160-K199 PolarHBondContact O-NZ 2.68Å; N163-K199 HydrophobicContact CB-CB 4.39Å; N163-K199 WeakPolarHBondContact CB-O 3.25Å; N163-K199 PolarHBondContact N-O 2.79Å; D197-K199 PolarHBondContact O-N 3.43Å; D197-K199 PolarHBondContact OD1-N 2.79Å; K199-T201 PolarHBondContact O-N 3.31Å
200N78Confident68.1Low80 Ų8050.7 Ų50.743%0.42828%0.275SS..SBendtrans64.222.2-174.9-159.143.6000113.8D162 L164 D197D162-N200 WeakPolarHBondContact OD1-CB 3.48Å; L164-N200 WeakPolarHBondContact CB-O 3.43Å; L164-N200 PolarHBondContact O-ND2 3.46Å; D197-N200 VanDerWaalsContact OD1-CA 3.3Å; D197-N200 WeakPolarHBondContact OD1-CA 3.49Å; D197-N200 PolarHBondContact OD1-N 3.49Å; D197-N200 PolarHBondContact OD2-N 2.88Å
201T79.1Confident70.1Confident3 Ų351.4 Ų51.42%0.01826%0.264CS..  trans-129.999.2174.1-550000108.5N163 L164 D197 L198 K199 I203N163-T201 WeakPolarHBondContact CB-OG1 3.38Å; N163-T201 PolarHBondContact ND2-OG1 3.28Å; L164-T201 VanDerWaalsContact CB-OG1 3.3Å; L164-T201 WeakPolarHBondContact CB-OG1 3.42Å; D197-T201 PolarHBondContact OD1-N 2.94Å; L198-T201 PolarHBondContact N-O 3.24Å; L198-T201 WeakPolarHBondContact O-CB 3.28Å; K199-T201 PolarHBondContact O-N 3.31Å; T201-I203 HydrophobicContact CG2-CD1 4.24Å; T201-I203 HydrophobicContact CG2-CG1 3.94Å; T201-I203 PolarHBondContact O-N 2.69Å
202T81.4Confident72.2Confident39 Ų3949.6 Ų49.624%0.23924%0.24CC..EExtended strand (participates in β ladder)trans-77.4111.8178.647.20000110.4G179 E180 D197G179-T202 WeakPolarHBondContact CA-O 3.2Å; E180-T202 WeakPolarHBondContact CB-OG1 3.41Å; E180-T202 WeakPolarHBondContact CG-OG1 3.37Å; E180-T202 VanDerWaalsContact OE2-CB 3.23Å; E180-T202 WeakPolarHBondContact OE2-CB 3.33Å; E180-T202 VanDerWaalsContact OE2-CG2 3.26Å; E180-T202 WeakPolarHBondContact OE2-CG2 3.27Å; E180-T202 PolarHBondContact OE2-OG1 2.87Å; D197-T202 HydrophobicContact CB-CG2 4.28Å
203I78.6Confident73.7Confident0 Ų052 Ų520%025%0.252CS..EExtended strand (participates in β ladder)trans-109.8127.6-177.7-59.5176.4000108.3F177 L195 F196 L198 T201 N209F177-I203 HydrophobicContact CB-CD1 4.06Å; F177-I203 HydrophobicContact CB-CG1 3.93Å; F177-I203 HydrophobicContact CB-CG2 3.99Å; F177-I203 HydrophobicContact CD1-CD1 4.42Å; F177-I203 HydrophobicContact CD2-CD1 3.87Å; F177-I203 HydrophobicContact CD2-CG1 4.47Å; F177-I203 HydrophobicContact CE2-CD1 4.42Å; F177-I203 HydrophobicContact CG-CD1 3.87Å; F177-I203 HydrophobicContact CG-CG1 4.3Å; L195-I203 WeakPolarHBondContact CA-O 3.41Å; F196-I203 HydrophobicContact CD1-CB 4.4Å; F196-I203 WeakPolarHBondContact CD1-O 3.44Å; F196-I203 HydrophobicContact CD2-CB 4.29Å; F196-I203 HydrophobicContact CE1-CB 3.91Å; F196-I203 HydrophobicContact CE1-CG2 3.68Å; F196-I203 WeakPolarHBondContact CE1-O 3.28Å; F196-I203 HydrophobicContact CE2-CB 3.79Å; F196-I203 HydrophobicContact CE2-CD1 4.06Å; F196-I203 HydrophobicContact CE2-CG1 4.41Å; F196-I203 HydrophobicContact CE2-CG2 4.11Å; F196-I203 HydrophobicContact CZ-CB 3.58Å; F196-I203 HydrophobicContact CZ-CD1 4.31Å; F196-I203 HydrophobicContact CZ-CG2 3.4Å; F196-I203 VanDerWaalsContact CZ-CG2 3.4Å; F196-I203 PolarHBondContact N-O 2.72Å; F196-I203 PolarHBondContact O-N 2.84Å; L198-I203 HydrophobicContact CB-CD1 3.99Å; L198-I203 HydrophobicContact CD2-CD1 3.93Å; T201-I203 HydrophobicContact CG2-CD1 4.24Å; T201-I203 HydrophobicContact CG2-CG1 3.94Å; T201-I203 PolarHBondContact O-N 2.69Å; I203-N209 HydrophobicContact CG2-CB 3.92Å; I203-N209 WeakPolarHBondContact CG2-ND2 3.07Å
204R76.8Confident74.9Confident59 Ų5948 Ų4822%0.22324%0.244CC..EExtended strand (participates in β ladder)trans-73.5137.3176.1-166.3169.3-75.996.16.3110.2S178 G179 S192 T206 N209S178-R204 PolarHBondContact O-N 2.94Å; G179-R204 PolarHBondContact O-NH1 3.12Å; G179-R204 PolarHBondContact O-NH2 3.44Å; S192-R204 WeakPolarHBondContact O-CD 3.32Å; S192-R204 WeakPolarHBondContact O-CG 3.46Å; R204-T206 VanDerWaalsContact C-N 3.27Å; R204-T206 HydrophobicContact CB-CG2 4.16Å; R204-T206 HydrophobicContact CG-CG2 3.87Å; R204-T206 PolarHBondContact O-N 3.22Å; R204-N209 WeakPolarHBondContact O-CB 3.44Å; R204-N209 PolarHBondContact O-ND2 3.28Å
205F68.4Low76.3Confident56 Ų5645.5 Ų45.525%0.24623%0.231CC..  trans-79.176.4-178.4-167.5-110.6000110.4S192 L194 F196 V210 L516 L519S192-F205 WeakPolarHBondContact CB-O 3.31Å; S192-F205 PolarHBondContact OG-O 3.45Å; L194-F205 HydrophobicContact CB-CB 4.02Å; L194-F205 WeakPolarHBondContact O-CB 3.21Å; L194-F205 PolarHBondContact O-N 3.31Å; F196-F205 HydrophobicContact CD1-CB 4.33Å; F196-F205 HydrophobicContact CD1-CD2 4.21Å; F196-F205 HydrophobicContact CE1-CB 4.45Å; F196-F205 HydrophobicContact CE1-CD2 4.03Å; F205-V210 HydrophobicContact CE2-CG2 4.35Å; F205-L516 HydrophobicContact CD1-CD1 3.94Å; F205-L516 HydrophobicContact CD1-CD2 4.41Å; F205-L516 HydrophobicContact CD1-CG 3.87Å; F205-L516 HydrophobicContact CE1-CD1 3.37Å; F205-L516 HydrophobicContact CE1-CG 3.64Å; F205-L516 HydrophobicContact CZ-CD1 3.8Å; F205-L516 WeakPolarHBondContact O-CD2 3.47Å; F205-L519 HydrophobicContact CE1-CD1 4.13Å; F205-L519 HydrophobicContact CZ-CD1 4.27Å
206T70.4Confident77.4Confident7 Ų745.1 Ų45.14%0.04323%0.231CC..  trans-110151.6176.573.70000110.3D187 R204 K208 N209 V210D187-T206 HydrophobicContact CB-CG2 4.34Å; D187-T206 PolarHBondContact OD2-OG1 3.5Å; R204-T206 VanDerWaalsContact C-N 3.27Å; R204-T206 HydrophobicContact CB-CG2 4.16Å; R204-T206 HydrophobicContact CG-CG2 3.87Å; R204-T206 PolarHBondContact O-N 3.22Å; T206-K208 PolarHBondContact O-N 2.92Å; T206-N209 PolarHBondContact O-N 2.77Å; T206-N209 WeakPolarHBondContact OG1-CB 3.33Å; T206-N209 PolarHBondContact OG1-N 2.85Å; T206-V210 PolarHBondContact O-N 3.28Å
207S70Confident78Confident33 Ų3345.1 Ų45.123%0.23123%0.234CC..Hα-helixtrans-57.8-31.5172.556.50000112.3Y211S207-Y211 WeakPolarHBondContact O-CB 3.26Å; S207-Y211 PolarHBondContact O-N 3.11Å
208K81.6Confident78.5Confident65 Ų6545.3 Ų45.328%0.28323%0.23SC..Hα-helixtrans-68-39173.3-66.9173.4-177.4169.80112.6D187 E189 T206 Y211 R212D187-K208 HydrophobicContact CB-CD 4.38Å; D187-K208 VanDerWaalsContact OD1-CD 3.27Å; D187-K208 WeakPolarHBondContact OD1-CD 3.42Å; D187-K208 WeakPolarHBondContact OD2-CB 3.35Å; E189-K208 WeakPolarHBondContact OE2-CE 3.34Å; E189-K208 IonicContact OE2-NZ 2.68Å; E189-K208 PolarHBondContact OE2-NZ 3.06Å; T206-K208 PolarHBondContact O-N 2.92Å; K208-Y211 PolarHBondContact O-N 3.47Å; K208-R212 WeakPolarHBondContact O-CB 3.46Å; K208-R212 VanDerWaalsContact O-CG 3.25Å; K208-R212 WeakPolarHBondContact O-CG 3.18Å; K208-R212 PolarHBondContact O-N 3.4Å
209N82.8Confident79.2Confident1 Ų142 Ų421%0.00521%0.213CC..Hα-helixtrans-71.3-37.2173.4-82.2-17.5000112.9S178 I203 R204 T206 Y211 R212 I213S178-N209 PolarHBondContact N-ND2 3.14Å; S178-N209 PolarHBondContact N-OD1 3.27Å; S178-N209 PolarHBondContact O-ND2 2.89Å; I203-N209 HydrophobicContact CG2-CB 3.92Å; I203-N209 WeakPolarHBondContact CG2-ND2 3.07Å; R204-N209 WeakPolarHBondContact O-CB 3.44Å; R204-N209 PolarHBondContact O-ND2 3.28Å; T206-N209 PolarHBondContact O-N 2.77Å; T206-N209 WeakPolarHBondContact OG1-CB 3.33Å; T206-N209 PolarHBondContact OG1-N 2.85Å; N209-Y211 VanDerWaalsContact C-N 3.31Å; N209-Y211 PolarHBondContact O-N 2.95Å; N209-R212 WeakPolarHBondContact O-CB 3.19Å; N209-R212 PolarHBondContact O-N 2.8Å; N209-R212 VanDerWaalsContact OD1-CD 3.32Å; N209-R212 WeakPolarHBondContact OD1-CD 3.44Å; N209-R212 PolarHBondContact OD1-NH1 3.09Å; N209-I213 WeakPolarHBondContact O-CG1 3.46Å; N209-I213 PolarHBondContact O-N 3.13Å
210V75Confident79.5Confident50 Ų5039.3 Ų39.330%0.30320%0.203SC..Hα-helixtrans-59.7-44.2170.2175.10000110.6F205 T206 I213 G214 V512F205-V210 HydrophobicContact CE2-CG2 4.35Å; T206-V210 PolarHBondContact O-N 3.28Å; V210-I213 PolarHBondContact O-N 3.36Å; V210-G214 PolarHBondContact O-N 2.88Å; V210-G214 VanDerWaalsContact O-N 3.08Å; V210-V512 HydrophobicContact CB-CG1 4.08Å; V210-V512 HydrophobicContact CG1-CG1 3.96Å; V210-V512 HydrophobicContact CG2-CG1 4.34Å
211Y81.1Confident79.9Confident108 Ų10837.8 Ų37.842%0.42419%0.193SC..Hα-helixtrans-60.8-45.5173.1174.1-102.3000112.6S207 K208 N209 I213 G214 V215 M228S207-Y211 WeakPolarHBondContact O-CB 3.26Å; S207-Y211 PolarHBondContact O-N 3.11Å; K208-Y211 PolarHBondContact O-N 3.47Å; N209-Y211 VanDerWaalsContact C-N 3.31Å; N209-Y211 PolarHBondContact O-N 2.95Å; Y211-I213 VanDerWaalsContact C-N 3.34Å; Y211-I213 PolarHBondContact O-N 3.42Å; Y211-G214 WeakPolarHBondContact O-CA 3.49Å; Y211-G214 PolarHBondContact O-N 2.88Å; Y211-G214 VanDerWaalsContact O-N 3.07Å; Y211-V215 HydrophobicContact CE1-CG1 4.12Å; Y211-V215 HydrophobicContact CE1-CG2 4.39Å; Y211-V215 HydrophobicContact CE2-CG1 3.96Å; Y211-V215 WeakPolarHBondContact O-CG2 3.41Å; Y211-V215 PolarHBondContact O-N 2.9Å; Y211-M228 HydrophobicContact CE1-CE 3.7Å
212R86.3Confident80.2Confident17 Ų1737.7 Ų37.76%0.06419%0.192CC..Hα-helixtrans-57.4-42.6175.3-76.1164.4-176127.97.3112.5L11 P176 F177 D187 K208 N209 G214 V215 A216L11-R212 HydrophobicContact CD1-CB 3.73Å; L11-R212 HydrophobicContact CD1-CG 4.16Å; L11-R212 VanDerWaalsContact CD1-O 3.27Å; L11-R212 WeakPolarHBondContact CD1-O 3.11Å; P176-R212 VanDerWaalsContact O-CD 3.25Å; P176-R212 WeakPolarHBondContact O-CD 3.27Å; P176-R212 PolarHBondContact O-NE 2.9Å; F177-R212 HydrophobicContact CD1-CB 3.73Å; F177-R212 HydrophobicContact CE1-CB 3.88Å; D187-R212 IonicContact OD1-CZ 3.89Å; D187-R212 VanDerWaalsContact OD1-CZ 3.29Å; D187-R212 IonicContact OD1-NH1 3.27Å; D187-R212 PolarHBondContact OD1-NH1 3.28Å; D187-R212 IonicContact OD1-NH2 3.15Å; D187-R212 PolarHBondContact OD1-NH2 2.98Å; D187-R212 IonicContact OD2-CZ 2.71Å; D187-R212 IonicContact OD2-NH1 2.69Å; D187-R212 PolarHBondContact OD2-NH1 3.35Å; K208-R212 WeakPolarHBondContact O-CB 3.46Å; K208-R212 VanDerWaalsContact O-CG 3.25Å; K208-R212 WeakPolarHBondContact O-CG 3.18Å; K208-R212 PolarHBondContact O-N 3.4Å; N209-R212 WeakPolarHBondContact O-CB 3.19Å; N209-R212 PolarHBondContact O-N 2.8Å; N209-R212 VanDerWaalsContact OD1-CD 3.32Å; N209-R212 WeakPolarHBondContact OD1-CD 3.44Å; N209-R212 PolarHBondContact OD1-NH1 3.09Å; R212-G214 VanDerWaalsContact C-N 3.3Å; R212-G214 PolarHBondContact O-N 2.91Å; R212-V215 WeakPolarHBondContact O-CG2 3.21Å; R212-V215 PolarHBondContact O-N 2.87Å; R212-A216 WeakPolarHBondContact O-CB 3.43Å; R212-A216 PolarHBondContact O-N 2.92Å
213I80.4Confident80.5Confident57 Ų5738.7 Ų38.729%0.29220%0.196SC..Hα-helixtrans-63.3-39.8175.2-67.7163.4000110.5F177 F196 N209 V210 Y211 A216 L217F177-I213 HydrophobicContact CD1-CG1 4.17Å; F177-I213 HydrophobicContact CE1-CG1 3.7Å; F177-I213 HydrophobicContact CZ-CG1 4.46Å; F196-I213 HydrophobicContact CE2-CD1 4.44Å; F196-I213 HydrophobicContact CZ-CD1 3.88Å; N209-I213 WeakPolarHBondContact O-CG1 3.46Å; N209-I213 PolarHBondContact O-N 3.13Å; V210-I213 PolarHBondContact O-N 3.36Å; Y211-I213 VanDerWaalsContact C-N 3.34Å; Y211-I213 PolarHBondContact O-N 3.42Å; I213-A216 PolarHBondContact O-N 3.34Å; I213-L217 PolarHBondContact O-N 3.04Å
214G76.4Confident80.9Confident34 Ų3440.8 Ų40.835%0.35121%0.209SC..Hα-helixtrans-57.2-50.4171.500000113.1V210 Y211 R212 L217 F218V210-G214 PolarHBondContact O-N 2.88Å; V210-G214 VanDerWaalsContact O-N 3.08Å; Y211-G214 WeakPolarHBondContact O-CA 3.49Å; Y211-G214 PolarHBondContact O-N 2.88Å; Y211-G214 VanDerWaalsContact O-N 3.07Å; R212-G214 VanDerWaalsContact C-N 3.3Å; R212-G214 PolarHBondContact O-N 2.91Å; G214-L217 PolarHBondContact O-N 3.39Å; G214-F218 PolarHBondContact O-N 3.31Å
215V85.2Confident81.5Confident10 Ų1038 Ų386%0.06120%0.199CC..Hα-helixtrans-76.5-19.6-178.7-66.30000114.7L11 Y211 R212 L217 F218 P220 M228L11-V215 HydrophobicContact CD1-CG2 4.26Å; L11-V215 HydrophobicContact CD2-CG2 3.77Å; L11-V215 HydrophobicContact CG-CG2 4.07Å; Y211-V215 HydrophobicContact CE1-CG1 4.12Å; Y211-V215 HydrophobicContact CE1-CG2 4.39Å; Y211-V215 HydrophobicContact CE2-CG1 3.96Å; Y211-V215 WeakPolarHBondContact O-CG2 3.41Å; Y211-V215 PolarHBondContact O-N 2.9Å; R212-V215 WeakPolarHBondContact O-CG2 3.21Å; R212-V215 PolarHBondContact O-N 2.87Å; V215-L217 VanDerWaalsContact C-N 3.28Å; V215-F218 WeakPolarHBondContact CA-O 3.18Å; V215-P220 HydrophobicContact CB-CG 4.06Å; V215-P220 HydrophobicContact CG1-CB 3.92Å; V215-P220 HydrophobicContact CG1-CG 3.94Å; V215-M228 HydrophobicContact CB-CE 4.49Å; V215-M228 HydrophobicContact CG2-CE 3.76Å; V215-M228 HydrophobicContact CG2-SD 4.34Å
216A86.3Confident82.4Confident9 Ų936.9 Ų36.97%0.07420%0.198CC..Hα-helixtrans-63.8-35.9168.100000111.8C8 F10 L11 F177 R212 I213C8-A216 WeakPolarHBondContact O-CB 3.25Å; F10-A216 PolarHBondContact N-O 3.29Å; L11-A216 HydrophobicContact CD1-CB 4.18Å; L11-A216 HydrophobicContact CG-CB 4.22Å; F177-A216 HydrophobicContact CZ-CB 4.35Å; R212-A216 WeakPolarHBondContact O-CB 3.43Å; R212-A216 PolarHBondContact O-N 2.92Å; I213-A216 PolarHBondContact O-N 3.34Å
217L80.9Confident83.4Confident69 Ų6940.2 Ų40.236%0.36122%0.215SC..Hα-helixtrans-94.2-21.4179.5-63.4175.4000113.9Y142 I213 G214 V215Y142-L217 WeakPolarHBondContact CE2-O 3.14Å; Y142-L217 PolarHBondContact OH-O 3.01Å; I213-L217 PolarHBondContact O-N 3.04Å; G214-L217 PolarHBondContact O-N 3.39Å; V215-L217 VanDerWaalsContact C-N 3.28Å
218F81.4Confident84.3Confident105 Ų10539.6 Ų39.646%0.46121%0.209SC..SBendtrans-138.3104.1-178.8-65.5-79.1000110.6L75 G214 V215L75-F218 HydrophobicContact CD1-CE1 4.32Å; L75-F218 HydrophobicContact CD1-CZ 4.26Å; G214-F218 PolarHBondContact O-N 3.31Å; V215-F218 WeakPolarHBondContact CA-O 3.18Å
219P85Confident84.9Confident8 Ų836.5 Ų36.55%0.05220%0.195CC..  trans-62.4128.4-168.416.8-25.5000112.1F10 A67 R68F10-P219 HydrophobicContact CB-CB 4.15Å; F10-P219 HydrophobicContact CD1-CB 3.8Å; F10-P219 HydrophobicContact CD1-CG 4.08Å; F10-P219 HydrophobicContact CD2-CB 4.09Å; F10-P219 HydrophobicContact CD2-CG 3.84Å; F10-P219 HydrophobicContact CE1-CB 4.17Å; F10-P219 HydrophobicContact CE1-CG 4.01Å; F10-P219 HydrophobicContact CE2-CB 4.42Å; F10-P219 HydrophobicContact CE2-CG 3.75Å; F10-P219 HydrophobicContact CG-CB 3.75Å; F10-P219 HydrophobicContact CG-CG 3.99Å; F10-P219 HydrophobicContact CZ-CB 4.46Å; F10-P219 HydrophobicContact CZ-CG 3.84Å; A67-P219 HydrophobicContact CB-CG 3.84Å; R68-P219 WeakPolarHBondContact CD-O 3.29Å; R68-P219 HydrophobicContact CG-CB 4.43Å; R68-P219 HydrophobicContact CG-CG 4.1Å; R68-P219 PolarHBondContact NH1-O 3.37Å
220P84.8Confident85.2Confident15 Ų1540.9 Ų40.910%0.09721%0.212CC..  trans-78.4-178.6179.834.1-33.9000110.9R68 V215 V224 M225 M228R68-P220 WeakPolarHBondContact CD-O 3.4Å; R68-P220 PolarHBondContact NE-O 3.28Å; R68-P220 VanDerWaalsContact NH1-C 3.34Å; V215-P220 HydrophobicContact CB-CG 4.06Å; V215-P220 HydrophobicContact CG1-CB 3.92Å; V215-P220 HydrophobicContact CG1-CG 3.94Å; P220-V224 HydrophobicContact CB-CB 4.02Å; P220-V224 HydrophobicContact CB-CG1 3.96Å; P220-V224 HydrophobicContact CG-CB 4.23Å; P220-V224 HydrophobicContact CG-CG1 4Å; P220-M225 HydrophobicContact CG-CG 3.8Å; P220-M228 HydrophobicContact CG-SD 4.31Å
221H85.5Confident86Confident49 Ų4941.4 Ų41.423%0.22721%0.211CC..  trans-62.8144.3176.3-173.3-97000110.8D223 V224 M225 E348H221-D223 IonicContact CE1-OD2 3.43Å; H221-D223 PolarHBondContact CE1-OD2 3.42Å; H221-D223 PolarHBondContact ND1-N 3.08Å; H221-D223 IonicContact ND1-OD2 3.36Å; H221-D223 PolarHBondContact ND1-OD2 3.07Å; H221-D223 VanDerWaalsContact ND1-OD2 3.17Å; H221-D223 PolarHBondContact O-N 3.03Å; H221-V224 WeakPolarHBondContact O-CA 3.35Å; H221-V224 WeakPolarHBondContact O-CB 3.5Å; H221-V224 PolarHBondContact O-N 2.87Å; H221-M225 PolarHBondContact O-N 3.28Å; H221-M225 VanDerWaalsContact O-N 3.16Å; H221-E348 IonicContact CD2-OE1 2.77Å; H221-E348 PolarHBondContact CD2-OE1 3.39Å; H221-E348 IonicContact NE2-OE1 3.87Å
222P86.3Confident86.5Confident1 Ų136.3 Ų36.31%0.00619%0.191CC..Hα-helixtrans-51.4-30.4-179.5-33.137.3000115.6L61 I65 M225 S226 A344 E348L61-P222 HydrophobicContact CD2-CB 4.26Å; I65-P222 HydrophobicContact CG1-CG 4.38Å; P222-M225 CarbonylContact O-C 3.49Å; P222-M225 PolarHBondContact O-N 3.23Å; P222-S226 PolarHBondContact O-N 2.95Å; P222-A344 HydrophobicContact CB-CB 4.24Å; P222-A344 HydrophobicContact CG-CB 4.49Å; P222-E348 VanDerWaalsContact CD-CD 3.47Å; P222-E348 WeakPolarHBondContact CD-OE2 3.36Å; P222-E348 HydrophobicContact CG-CB 4.13Å; P222-E348 WeakPolarHBondContact CG-OE2 3.35Å
223D86.4Confident86.7Confident59 Ų5935.5 Ų35.532%0.31619%0.188SC..Hα-helixtrans-62.5-41.7173.7-63.9-27.1000111.9H221 S226 D227 S345 K349H221-D223 IonicContact CE1-OD2 3.43Å; H221-D223 PolarHBondContact CE1-OD2 3.42Å; H221-D223 PolarHBondContact ND1-N 3.08Å; H221-D223 IonicContact ND1-OD2 3.36Å; H221-D223 PolarHBondContact ND1-OD2 3.07Å; H221-D223 VanDerWaalsContact ND1-OD2 3.17Å; H221-D223 PolarHBondContact O-N 3.03Å; D223-S226 WeakPolarHBondContact O-CB 3.16Å; D223-S226 PolarHBondContact O-N 3Å; D223-D227 PolarHBondContact O-N 2.95Å; D223-D227 VanDerWaalsContact O-N 3.08Å; D223-S345 WeakPolarHBondContact OD1-CB 3.22Å; D223-S345 PolarHBondContact OD1-OG 3.37Å; D223-K349 IonicContact OD1-NZ 3.67Å; D223-K349 PolarHBondContact OD1-NZ 3.46Å; D223-K349 WeakPolarHBondContact OD2-CE 3.49Å; D223-K349 IonicContact OD2-NZ 2.69Å; D223-K349 PolarHBondContact OD2-NZ 2.91Å
224V87.7Confident87Confident45 Ų4536.2 Ų36.227%0.27319%0.19SC..Hα-helixtrans-68.8-37.1175.5179.70000110.7P220 H221 S226 D227 M228P220-V224 HydrophobicContact CB-CB 4.02Å; P220-V224 HydrophobicContact CB-CG1 3.96Å; P220-V224 HydrophobicContact CG-CB 4.23Å; P220-V224 HydrophobicContact CG-CG1 4Å; H221-V224 WeakPolarHBondContact O-CA 3.35Å; H221-V224 WeakPolarHBondContact O-CB 3.5Å; H221-V224 PolarHBondContact O-N 2.87Å; V224-S226 PolarHBondContact O-N 3.42Å; V224-D227 PolarHBondContact O-N 3.31Å; V224-M228 HydrophobicContact CG1-CE 3.49Å; V224-M228 VanDerWaalsContact CG1-CE 3.49Å; V224-M228 HydrophobicContact CG1-SD 4.06Å; V224-M228 WeakPolarHBondContact O-CG 3.34Å; V224-M228 PolarHBondContact O-N 3.28Å
225M89.1Confident87.7Confident1 Ų134.9 Ų34.91%0.00518%0.175CC..Hα-helixtrans-64.2-31.2172.7-59.8-169.672.500112I13 I60 L61 S64 P220 H221 P222 C229I13-M225 HydrophobicContact CB-CE 3.95Å; I13-M225 HydrophobicContact CG1-CB 4.29Å; I13-M225 HydrophobicContact CG1-CE 4.38Å; I13-M225 HydrophobicContact CG2-CB 4.19Å; I13-M225 HydrophobicContact CG2-CE 3.93Å; I60-M225 HydrophobicContact CG2-CE 3.97Å; L61-M225 HydrophobicContact CD2-CB 4.15Å; L61-M225 HydrophobicContact CD2-CE 4.38Å; L61-M225 HydrophobicContact CD2-SD 3.96Å; S64-M225 WeakPolarHBondContact OG-CE 3.41Å; P220-M225 HydrophobicContact CG-CG 3.8Å; H221-M225 PolarHBondContact O-N 3.28Å; H221-M225 VanDerWaalsContact O-N 3.16Å; P222-M225 CarbonylContact O-C 3.49Å; P222-M225 PolarHBondContact O-N 3.23Å; M225-C229 WeakPolarHBondContact O-CB 3.47Å; M225-C229 PolarHBondContact O-N 3.28Å
226S88.9Confident87.9Confident32 Ų3234.4 Ų34.422%0.22417%0.172CC..Hα-helixtrans-67.5-43.7172.8-169.50000112.2P222 D223 V224 C229 R230P222-S226 PolarHBondContact O-N 2.95Å; D223-S226 WeakPolarHBondContact O-CB 3.16Å; D223-S226 PolarHBondContact O-N 3Å; V224-S226 PolarHBondContact O-N 3.42Å; S226-C229 WeakPolarHBondContact O-CB 3.38Å; S226-C229 PolarHBondContact O-N 2.91Å; S226-R230 WeakPolarHBondContact O-CB 3.48Å; S226-R230 PolarHBondContact O-N 2.87Å
227D89.5Confident87.8Confident77 Ų7734.5 Ų34.541%0.41217%0.171SC..Hα-helixtrans-62.8-40.5173.2-74.8-46.4000112D223 V224 R230 Q231D223-D227 PolarHBondContact O-N 2.95Å; D223-D227 VanDerWaalsContact O-N 3.08Å; V224-D227 PolarHBondContact O-N 3.31Å; D227-R230 PolarHBondContact O-N 3.32Å; D227-R230 IonicContact OD1-CZ 3.09Å; D227-R230 IonicContact OD1-NH1 2.87Å; D227-R230 PolarHBondContact OD1-NH1 3.02Å; D227-R230 IonicContact OD1-NH2 3.24Å; D227-R230 PolarHBondContact OD1-NH2 2.98Å; D227-Q231 WeakPolarHBondContact O-CB 3.33Å; D227-Q231 PolarHBondContact O-N 3.15Å
228M90.8Very high87.8Confident19 Ų1935.6 Ų35.69%0.09417%0.171CC..Hα-helixtrans-66.8-37.7175.1-69.6164.6179.400112.7L11 I13 Y211 V215 P220 V224 Q231 G232L11-M228 HydrophobicContact CD2-CE 4.33Å; L11-M228 HydrophobicContact CD2-CG 4.35Å; L11-M228 HydrophobicContact CD2-SD 3.51Å; L11-M228 VanDerWaalsContact CD2-SD 3.51Å; I13-M228 HydrophobicContact CG2-CB 4.08Å; Y211-M228 HydrophobicContact CE1-CE 3.7Å; V215-M228 HydrophobicContact CB-CE 4.49Å; V215-M228 HydrophobicContact CG2-CE 3.76Å; V215-M228 HydrophobicContact CG2-SD 4.34Å; P220-M228 HydrophobicContact CG-SD 4.31Å; V224-M228 HydrophobicContact CG1-CE 3.49Å; V224-M228 VanDerWaalsContact CG1-CE 3.49Å; V224-M228 HydrophobicContact CG1-SD 4.06Å; V224-M228 WeakPolarHBondContact O-CG 3.34Å; V224-M228 PolarHBondContact O-N 3.28Å; M228-Q231 PolarHBondContact O-N 3.01Å; M228-G232 PolarHBondContact O-N 3Å; M228-G232 VanDerWaalsContact O-N 3.15Å
229C92.4Very high88Confident0 Ų031.2 Ų31.20%015%0.151CC..Hα-helixtrans-62.8-44.3172.1-1630000111.2I13 G17 M225 S226 G232 F233 L333 L341I13-C229 HydrophobicContact CG1-CB 3.94Å; G17-C229 VanDerWaalsContact CA-O 3.31Å; G17-C229 WeakPolarHBondContact CA-O 3.48Å; M225-C229 WeakPolarHBondContact O-CB 3.47Å; M225-C229 PolarHBondContact O-N 3.28Å; S226-C229 WeakPolarHBondContact O-CB 3.38Å; S226-C229 PolarHBondContact O-N 2.91Å; C229-G232 PolarHBondContact O-N 3.48Å; C229-F233 PolarHBondContact O-N 3.03Å; C229-L333 HydrophobicContact CB-CD1 4.05Å; C229-L341 HydrophobicContact CB-CD1 4.08Å
230R90.8Very high87.7Confident94 Ų9431 Ų3136%0.35515%0.149SC..Hα-helixtrans-65.1-40.9177-168.3-175.964.7-107.3-9.8111.2S226 D227 F233 E234 L333S226-R230 WeakPolarHBondContact O-CB 3.48Å; S226-R230 PolarHBondContact O-N 2.87Å; D227-R230 PolarHBondContact O-N 3.32Å; D227-R230 IonicContact OD1-CZ 3.09Å; D227-R230 IonicContact OD1-NH1 2.87Å; D227-R230 PolarHBondContact OD1-NH1 3.02Å; D227-R230 IonicContact OD1-NH2 3.24Å; D227-R230 PolarHBondContact OD1-NH2 2.98Å; R230-F233 WeakPolarHBondContact O-CB 3.45Å; R230-F233 PolarHBondContact O-N 3.2Å; R230-E234 WeakPolarHBondContact CD-OE1 3.41Å; R230-E234 HydrophobicContact CG-CG 4.28Å; R230-E234 WeakPolarHBondContact CG-OE1 3.28Å; R230-E234 IonicContact NE-OE1 3.2Å; R230-E234 PolarHBondContact NE-OE1 3.33Å; R230-E234 VanDerWaalsContact NE-OE1 3.15Å; R230-E234 WeakPolarHBondContact O-CB 3.26Å; R230-E234 WeakPolarHBondContact O-CG 3.44Å; R230-E234 PolarHBondContact O-N 3.41Å; R230-L333 HydrophobicContact CB-CD1 4.07Å; R230-L333 HydrophobicContact CB-CG 4.34Å
231Q90.3Very high87.1Confident61 Ų6132.3 Ų32.329%0.28516%0.162SC..Hα-helixtrans-57.9-49.6176.6-179.9159.960.400111.6Y14 P185 D227 M228 F233 E234 D235Y14-Q231 HydrophobicContact CE2-CG 4.16Å; P185-Q231 HydrophobicContact CG-CG 4.49Å; D227-Q231 WeakPolarHBondContact O-CB 3.33Å; D227-Q231 PolarHBondContact O-N 3.15Å; M228-Q231 PolarHBondContact O-N 3.01Å; Q231-F233 VanDerWaalsContact C-N 3.28Å; Q231-F233 PolarHBondContact O-N 3.41Å; Q231-E234 PolarHBondContact O-N 3.47Å; Q231-E234 VanDerWaalsContact O-N 3.16Å; Q231-D235 WeakPolarHBondContact CG-OD2 3.45Å; Q231-D235 WeakPolarHBondContact O-CB 3.45Å; Q231-D235 PolarHBondContact O-N 2.98Å
232G91.7Very high86.4Confident0 Ų037.6 Ų37.60%018%0.18CC..Hα-helixtrans-62.2-32.7177.500000114.4Y14 V18 M228 C229 T236Y14-G232 VanDerWaalsContact CD2-CA 3.43Å; V18-G232 WeakPolarHBondContact CG2-O 3.19Å; M228-G232 PolarHBondContact O-N 3Å; M228-G232 VanDerWaalsContact O-N 3.15Å; C229-G232 PolarHBondContact O-N 3.48Å; G232-T236 WeakPolarHBondContact O-CB 3.3Å; G232-T236 PolarHBondContact O-N 2.86Å; G232-T236 VanDerWaalsContact O-N 3.15Å; G232-T236 PolarHBondContact O-OG1 3.45Å
233F90.5Very high85.5Confident1 Ų140.1 Ų40.10%0.00419%0.191CC..Hα-helixtrans-68.9-46.2172.8-178.5-92000112G17 A20 A21 Y25 C229 R230 Q231 T236 L237 G332 L333 P334G17-F233 WeakPolarHBondContact O-CA 2.78Å; A20-F233 HydrophobicContact CB-CD2 4.03Å; A20-F233 HydrophobicContact CB-CE2 4.4Å; A21-F233 HydrophobicContact CB-CD2 3.62Å; A21-F233 HydrophobicContact CB-CE2 4.06Å; A21-F233 HydrophobicContact CB-CG 4.13Å; Y25-F233 HydrophobicContact CE2-CE2 4.14Å; Y25-F233 AromaticContact CE2-CZ 3.72Å; Y25-F233 HydrophobicContact CE2-CZ 3.72Å; C229-F233 PolarHBondContact O-N 3.03Å; R230-F233 WeakPolarHBondContact O-CB 3.45Å; R230-F233 PolarHBondContact O-N 3.2Å; Q231-F233 VanDerWaalsContact C-N 3.28Å; Q231-F233 PolarHBondContact O-N 3.41Å; F233-T236 PolarHBondContact O-N 3.28Å; F233-L237 HydrophobicContact CD1-CD1 3.91Å; F233-L237 HydrophobicContact CE1-CD1 3.6Å; F233-L237 HydrophobicContact CE1-CG 4.46Å; F233-L237 HydrophobicContact CZ-CD1 4.3Å; F233-L237 WeakPolarHBondContact O-CG 3.35Å; F233-L237 PolarHBondContact O-N 3.08Å; F233-G332 WeakPolarHBondContact CE1-O 3.44Å; F233-G332 WeakPolarHBondContact CZ-O 3.44Å; F233-L333 HydrophobicContact CB-CD2 3.68Å; F233-L333 HydrophobicContact CD2-CD2 3.99Å; F233-L333 HydrophobicContact CG-CD2 3.85Å; F233-P334 HydrophobicContact CE2-CG 4.21Å
234E87.5Confident83.8Confident72 Ų7238.1 Ų38.134%0.33619%0.185SC..Hα-helixtrans-66.8-40.2177.9-73.2173.3-16700112.8R230 Q231 L237 R238R230-E234 WeakPolarHBondContact CD-OE1 3.41Å; R230-E234 HydrophobicContact CG-CG 4.28Å; R230-E234 WeakPolarHBondContact CG-OE1 3.28Å; R230-E234 IonicContact NE-OE1 3.2Å; R230-E234 PolarHBondContact NE-OE1 3.33Å; R230-E234 VanDerWaalsContact NE-OE1 3.15Å; R230-E234 WeakPolarHBondContact O-CB 3.26Å; R230-E234 WeakPolarHBondContact O-CG 3.44Å; R230-E234 PolarHBondContact O-N 3.41Å; Q231-E234 PolarHBondContact O-N 3.47Å; Q231-E234 VanDerWaalsContact O-N 3.16Å; E234-L237 PolarHBondContact O-N 2.9Å; E234-R238 PolarHBondContact O-N 3.4Å
235D90Very high81.5Confident6 Ų641.2 Ų41.23%0.03221%0.209CC..Hα-helixtrans-65.9-40.2177.4-66.2-27.2000110.9Y14 I183 P185 Q231 R238 F239Y14-D235 PolarHBondContact OH-OD2 2.8Å; I183-D235 HydrophobicContact CG2-CB 4.49Å; P185-D235 WeakPolarHBondContact CA-OD2 3.42Å; Q231-D235 WeakPolarHBondContact CG-OD2 3.45Å; Q231-D235 WeakPolarHBondContact O-CB 3.45Å; Q231-D235 PolarHBondContact O-N 2.98Å; D235-R238 WeakPolarHBondContact O-CB 3.45Å; D235-R238 PolarHBondContact O-N 2.89Å; D235-R238 IonicContact OD1-CZ 2.62Å; D235-R238 VanDerWaalsContact OD1-CZ 3.27Å; D235-R238 IonicContact OD1-NH1 3.54Å; D235-R238 PolarHBondContact OD1-NH1 2.87Å; D235-R238 IonicContact OD1-NH2 3.79Å; D235-R238 PolarHBondContact OD1-NH2 3.29Å; D235-F239 PolarHBondContact O-N 3.16Å
236T89.2Confident79.3Confident0 Ų047.1 Ų47.10%024%0.239CC..Hα-helixtrans-64.1-45172.3-57.60000112V18 A21 I22 I183 G232 F233 R238 F239 L240V18-T236 WeakPolarHBondContact CA-OG1 3.45Å; V18-T236 HydrophobicContact CG1-CG2 4.48Å; V18-T236 WeakPolarHBondContact CG1-OG1 3.17Å; V18-T236 WeakPolarHBondContact CG2-OG1 3.28Å; A21-T236 HydrophobicContact CB-CG2 3.5Å; A21-T236 VanDerWaalsContact CB-CG2 3.5Å; I22-T236 HydrophobicContact CG1-CG2 4.03Å; I183-T236 HydrophobicContact CD1-CG2 4.19Å; I183-T236 WeakPolarHBondContact CG2-OG1 3.3Å; G232-T236 WeakPolarHBondContact O-CB 3.3Å; G232-T236 PolarHBondContact O-N 2.86Å; G232-T236 VanDerWaalsContact O-N 3.15Å; G232-T236 PolarHBondContact O-OG1 3.45Å; F233-T236 PolarHBondContact O-N 3.28Å; T236-R238 PolarHBondContact O-N 3.17Å; T236-F239 PolarHBondContact O-N 3.19Å; T236-L240 HydrophobicContact CG2-CD1 4.01Å; T236-L240 HydrophobicContact CG2-CG 4.18Å; T236-L240 VanDerWaalsContact O-CG 3.32Å; T236-L240 WeakPolarHBondContact O-CG 3.41Å; T236-L240 PolarHBondContact O-N 3.04Å
237L84.2Confident76.7Confident10 Ų1052.9 Ų52.95%0.05226%0.256CS..Hα-helixtrans-59-38175-76178.2000111.8Y25 F233 E234 A241 A328Y25-L237 HydrophobicContact CD1-CD2 4.08Å; Y25-L237 HydrophobicContact CD2-CD2 3.61Å; Y25-L237 HydrophobicContact CE1-CD2 4.4Å; Y25-L237 HydrophobicContact CE2-CD2 3.98Å; Y25-L237 HydrophobicContact CG-CD2 3.69Å; F233-L237 HydrophobicContact CD1-CD1 3.91Å; F233-L237 HydrophobicContact CE1-CD1 3.6Å; F233-L237 HydrophobicContact CE1-CG 4.46Å; F233-L237 HydrophobicContact CZ-CD1 4.3Å; F233-L237 WeakPolarHBondContact O-CG 3.35Å; F233-L237 PolarHBondContact O-N 3.08Å; E234-L237 PolarHBondContact O-N 2.9Å; L237-A241 VanDerWaalsContact O-CB 3.25Å; L237-A241 WeakPolarHBondContact O-CB 3.49Å; L237-A241 PolarHBondContact O-N 3.17Å; L237-A328 HydrophobicContact CD1-CB 3.84Å; L237-A328 HydrophobicContact CD2-CB 3.75Å; L237-A328 HydrophobicContact CG-CB 4.42Å
238R82.9Confident74.3Confident93 Ų9357.8 Ų57.835%0.35128%0.276SS..Hα-helixtrans-65.7-40.9175.8-160-177.3-49.9104.78.2112.1E234 D235 T236 R242E234-R238 PolarHBondContact O-N 3.4Å; D235-R238 WeakPolarHBondContact O-CB 3.45Å; D235-R238 PolarHBondContact O-N 2.89Å; D235-R238 IonicContact OD1-CZ 2.62Å; D235-R238 VanDerWaalsContact OD1-CZ 3.27Å; D235-R238 IonicContact OD1-NH1 3.54Å; D235-R238 PolarHBondContact OD1-NH1 2.87Å; D235-R238 IonicContact OD1-NH2 3.79Å; D235-R238 PolarHBondContact OD1-NH2 3.29Å; T236-R238 PolarHBondContact O-N 3.17Å; R238-R242 WeakPolarHBondContact O-CB 3.5Å; R238-R242 WeakPolarHBondContact O-CG 3.26Å; R238-R242 PolarHBondContact O-N 3.34Å
239F84.7Confident71.7Confident13 Ų1361.8 Ų61.86%0.05730%0.301CS..Hα-helixtrans-63.3-52.8173.3173.5-92.6000111.7I172 D182 I183 D235 T236 A241 R242 H243I172-F239 HydrophobicContact CD1-CE1 4Å; I172-F239 HydrophobicContact CD1-CZ 4.06Å; I172-F239 HydrophobicContact CG1-CE1 4.43Å; I172-F239 HydrophobicContact CG1-CZ 4.04Å; I172-F239 HydrophobicContact CG2-CE1 3.88Å; I172-F239 HydrophobicContact CG2-CE2 4.28Å; I172-F239 HydrophobicContact CG2-CZ 3.67Å; D182-F239 HydrophobicContact CB-CD2 4.06Å; D182-F239 HydrophobicContact CB-CE2 3.66Å; D182-F239 HydrophobicContact CB-CZ 4.41Å; D182-F239 WeakPolarHBondContact O-CD2 3.29Å; I183-F239 HydrophobicContact CD1-CB 4.35Å; I183-F239 HydrophobicContact CD1-CD1 3.81Å; I183-F239 HydrophobicContact CD1-CE1 4.35Å; I183-F239 HydrophobicContact CD1-CG 4.06Å; I183-F239 HydrophobicContact CG1-CB 3.87Å; I183-F239 HydrophobicContact CG1-CD1 3.94Å; I183-F239 HydrophobicContact CG1-CD2 4.02Å; I183-F239 HydrophobicContact CG1-CG 3.66Å; D235-F239 PolarHBondContact O-N 3.16Å; T236-F239 PolarHBondContact O-N 3.19Å; F239-A241 VanDerWaalsContact C-N 3.26Å; F239-A241 PolarHBondContact O-N 2.8Å; F239-R242 PolarHBondContact O-N 3.25Å; F239-R242 VanDerWaalsContact O-N 3.16Å; F239-H243 AromaticContact CD2-CD2 3.37Å; F239-H243 WeakPolarHBondContact CD2-CD2 3.48Å; F239-H243 AromaticContact CD2-NE2 3.64Å; F239-H243 AromaticContact CE2-CD2 3.18Å; F239-H243 WeakPolarHBondContact CE2-CD2 3.14Å; F239-H243 AromaticContact CE2-CG 3.97Å; F239-H243 AromaticContact CE2-NE2 3.34Å; F239-H243 VanDerWaalsContact CE2-NE2 3.34Å; F239-H243 WeakPolarHBondContact CE2-NE2 3.12Å; F239-H243 AromaticContact CZ-CD2 3.7Å; F239-H243 PolarHBondContact O-CD2 3.24Å; F239-H243 PolarHBondContact O-N 3.01Å
240L79.3Confident69.2Low2 Ų268.7 Ų68.71%0.0134%0.337CS..Hα-helixtrans-59.1-36.8179.4-64.7176.3000112A26 T236 G244 L254 I255A26-L240 HydrophobicContact CB-CD1 4.23Å; A26-L240 HydrophobicContact CB-CD2 4.24Å; T236-L240 HydrophobicContact CG2-CD1 4.01Å; T236-L240 HydrophobicContact CG2-CG 4.18Å; T236-L240 VanDerWaalsContact O-CG 3.32Å; T236-L240 WeakPolarHBondContact O-CG 3.41Å; T236-L240 PolarHBondContact O-N 3.04Å; L240-G244 PolarHBondContact O-N 3.45Å; L240-L254 HydrophobicContact CD2-CB 4.2Å; L240-L254 HydrophobicContact CD2-CD1 4.07Å; L240-L254 HydrophobicContact CD2-CD2 4.17Å; L240-L254 HydrophobicContact CD2-CG 4.39Å; L240-I255 HydrophobicContact CB-CD1 4.28Å; L240-I255 HydrophobicContact CB-CG1 4.26Å
241A72.1Confident66.8Low44 Ų4465.9 Ų65.936%0.36433%0.329SS..Hα-helixtrans-68.3-46.6174.800000112.6L237 F239 G244L237-A241 VanDerWaalsContact O-CB 3.25Å; L237-A241 WeakPolarHBondContact O-CB 3.49Å; L237-A241 PolarHBondContact O-N 3.17Å; F239-A241 VanDerWaalsContact C-N 3.26Å; F239-A241 PolarHBondContact O-N 2.8Å; A241-G244 PolarHBondContact O-N 2.71Å
242R70.8Confident64.4Low159 Ų15965.2 Ų65.260%0.633%0.331SS*.Hα-helixtrans-60.2-52.6177.9-77.6172.9171.7-177.2-5.7111.9R238 F239 G244 S245 I246R238-R242 WeakPolarHBondContact O-CB 3.5Å; R238-R242 WeakPolarHBondContact O-CG 3.26Å; R238-R242 PolarHBondContact O-N 3.34Å; F239-R242 PolarHBondContact O-N 3.25Å; F239-R242 VanDerWaalsContact O-N 3.16Å; R242-G244 VanDerWaalsContact C-N 3.29Å; R242-G244 PolarHBondContact O-N 2.98Å; R242-S245 PolarHBondContact O-N 3.08Å; R242-I246 WeakPolarHBondContact O-CD1 3.4Å; R242-I246 WeakPolarHBondContact O-CG1 3.33Å; R242-I246 PolarHBondContact O-N 2.94Å
243H65.9Low62.4Low54 Ų5469.8 Ų69.825%0.2535%0.348CS..Hα-helixtrans-74.5-20.2-176.7-69.1-83.9000113.2F239 S245 L254F239-H243 AromaticContact CD2-CD2 3.37Å; F239-H243 WeakPolarHBondContact CD2-CD2 3.48Å; F239-H243 AromaticContact CD2-NE2 3.64Å; F239-H243 AromaticContact CE2-CD2 3.18Å; F239-H243 WeakPolarHBondContact CE2-CD2 3.14Å; F239-H243 AromaticContact CE2-CG 3.97Å; F239-H243 AromaticContact CE2-NE2 3.34Å; F239-H243 VanDerWaalsContact CE2-NE2 3.34Å; F239-H243 WeakPolarHBondContact CE2-NE2 3.12Å; F239-H243 AromaticContact CZ-CD2 3.7Å; F239-H243 PolarHBondContact O-CD2 3.24Å; F239-H243 PolarHBondContact O-N 3.01Å; H243-S245 VanDerWaalsContact C-N 3.25Å; H243-S245 PolarHBondContact O-N 2.79Å; H243-L254 HydrophobicContact CB-CD1 4.3Å
244G51.9Low60.6Low18 Ų1870.2 Ų70.219%0.18635%0.35CS..Hα-helixtrans-64.2-22.9168.800000114.6L240 A241 R242 S252L240-G244 PolarHBondContact O-N 3.45Å; A241-G244 PolarHBondContact O-N 2.71Å; R242-G244 VanDerWaalsContact C-N 3.29Å; R242-G244 PolarHBondContact O-N 2.98Å; G244-S252 CarbonylContact O-C 3.46Å; G244-S252 VanDerWaalsContact O-CA 3.22Å; G244-S252 WeakPolarHBondContact O-CA 3.29Å; G244-S252 VanDerWaalsContact O-O 3.07Å
245S39.4Very low59.1Low109 Ų10967.7 Ų67.776%0.76234%0.339SS*.Hα-helixtrans-105.3-15.6-178.4-62.30000115.1R242 H243R242-S245 PolarHBondContact O-N 3.08Å; H243-S245 VanDerWaalsContact C-N 3.25Å; H243-S245 PolarHBondContact O-N 2.79Å
246I41.5Very low57.4Low126 Ų12668.1 Ų68.165%0.64634%0.343SS*.Hα-helixtrans-105.3-15-162.4-67.7172.5000114.2R242R242-I246 WeakPolarHBondContact O-CD1 3.4Å; R242-I246 WeakPolarHBondContact O-CG1 3.33Å; R242-I246 PolarHBondContact O-N 2.94Å
247R34.8Very low55.8Low153 Ų15368.4 Ų68.458%0.57735%0.345SS*.  trans-126.5112.1176.2-77.6-177.1172.9139.55.5112.3T249 L251 S252R247-T249 PolarHBondContact O-N 2.73Å; R247-L251 HydrophobicContact CB-CB 4.17Å; R247-L251 HydrophobicContact CB-CD1 4.22Å; R247-S252 WeakPolarHBondContact O-CB 3.18Å; R247-S252 PolarHBondContact O-N 3.44Å
248H40.1Very low54.5Low179 Ų17972.6 Ų72.683%0.82937%0.371SS*.THydrogen-bonded Turntrans-66.615.6177.1-129.3-85000114.4
249T34.7Very low52.9Low103 Ų10377.1 Ų77.163%0.63239%0.388SS*.THydrogen-bonded Turntrans-136.593.7-165-36.10000109.2R247 L251R247-T249 PolarHBondContact O-N 2.73Å; T249-L251 PolarHBondContact O-N 2.86Å
250I40.7Very low51.4Low145 Ų14577.9 Ų77.974%0.74439%0.394SS*.THydrogen-bonded Turntrans64.6-39.2175-57.2176.7000116
251L40.7Very low50.2Low36 Ų3680.2 Ų80.219%0.18841%0.406CS..G310 helixtrans-71-24.3-179.2-81.2149.2000114.7M1 R247 T249 R253 L254M1-L251 HydrophobicContact CE-CD2 3.4Å; M1-L251 VanDerWaalsContact CE-CD2 3.4Å; M1-L251 HydrophobicContact CE-CG 3.71Å; M1-L251 HydrophobicContact SD-CD2 3.64Å; R247-L251 HydrophobicContact CB-CB 4.17Å; R247-L251 HydrophobicContact CB-CD1 4.22Å; T249-L251 PolarHBondContact O-N 2.86Å; L251-R253 PolarHBondContact O-N 2.7Å; L251-L254 HydrophobicContact CD2-CD1 4.17Å; L251-L254 WeakPolarHBondContact O-CG 3.41Å
252S39.3Very low49.1Very low46 Ų4680.6 Ų80.632%0.32241%0.41SS..G310 helixtrans-63.9-3.3-172.5540000116.3G244 R247G244-S252 CarbonylContact O-C 3.46Å; G244-S252 VanDerWaalsContact O-CA 3.22Å; G244-S252 WeakPolarHBondContact O-CA 3.29Å; G244-S252 VanDerWaalsContact O-O 3.07Å; R247-S252 WeakPolarHBondContact O-CB 3.18Å; R247-S252 PolarHBondContact O-N 3.44Å
253R49.2Very low48.3Very low96 Ų9676.9 Ų76.936%0.36240%0.404SS..G310 helixtrans-135.353.8-176.4-61.4179.9-174.8146.11.4110.9L251 R264 E315L251-R253 PolarHBondContact O-N 2.7Å; R253-R264 PolarHBondContact O-NH1 3.47Å; R253-R264 VanDerWaalsContact O-NH1 3.14Å; R253-E315 IonicContact CZ-OE1 3.17Å; R253-E315 IonicContact NH1-OE1 2.79Å; R253-E315 PolarHBondContact NH1-OE1 2.98Å; R253-E315 PolarHBondContact NH2-O 2.92Å; R253-E315 IonicContact NH2-OE1 2.83Å; R253-E315 PolarHBondContact NH2-OE1 3.06Å
254L53.6Low47.5Very low11 Ų1178.1 Ų78.16%0.05841%0.407CS..  trans-78.4-21.1173.6-84.6166.4000114Y25 A26 L29 L240 H243 L251Y25-L254 VanDerWaalsContact O-O 3.09Å; A26-L254 VanDerWaalsContact CA-O 3.27Å; A26-L254 WeakPolarHBondContact CA-O 3.36Å; A26-L254 HydrophobicContact CB-CD2 4.44Å; A26-L254 VanDerWaalsContact CB-O 3.26Å; A26-L254 WeakPolarHBondContact CB-O 3.38Å; L29-L254 HydrophobicContact CD1-CD2 3.96Å; L29-L254 HydrophobicContact CD2-CD2 3.91Å; L29-L254 HydrophobicContact CG-CD2 4.38Å; L240-L254 HydrophobicContact CD2-CB 4.2Å; L240-L254 HydrophobicContact CD2-CD1 4.07Å; L240-L254 HydrophobicContact CD2-CD2 4.17Å; L240-L254 HydrophobicContact CD2-CG 4.39Å; H243-L254 HydrophobicContact CB-CD1 4.3Å; L251-L254 HydrophobicContact CD2-CD1 4.17Å; L251-L254 WeakPolarHBondContact O-CG 3.41Å
255I55.8Low47.2Very low18 Ų1880.5 Ų80.59%0.09242%0.42CS..SBendtrans-107.496.3175.1-61.4176.8000108.3Y25 L240 T324 A325Y25-I255 HydrophobicContact CD1-CG2 4.39Å; Y25-I255 WeakPolarHBondContact O-CA 3.36Å; L240-I255 HydrophobicContact CB-CD1 4.28Å; L240-I255 HydrophobicContact CB-CG1 4.26Å; I255-T324 HydrophobicContact CG2-CG2 3.92Å; I255-A325 HydrophobicContact CD1-CB 3.58Å; I255-A325 HydrophobicContact CG2-CB 4.32Å
256S54.1Low47.5Very low16 Ų1678.7 Ų78.711%0.11241%0.408CS..  trans-92.2116.9-170.9-78.70000113Y25 D28Y25-S256 PolarHBondContact O-N 2.61Å; D28-S256 VanDerWaalsContact OD2-CB 3.27Å; D28-S256 WeakPolarHBondContact OD2-CB 3.35Å; D28-S256 PolarHBondContact OD2-OG 2.7Å
257C56.7Low47.6Very low6 Ų676.9 Ų76.94%0.04140%0.398CS..  trans-79.9152.8166.2900000111.5R259 C260 I261 R320 C321C257-R259 PolarHBondContact O-N 3.17Å; C257-R259 VanDerWaalsContact O-N 3.09Å; C257-C260 WeakPolarHBondContact O-CB 3.4Å; C257-C260 PolarHBondContact O-N 3.22Å; C257-I261 PolarHBondContact O-N 2.79Å; C257-R320 HydrophobicContact CB-CB 4.3Å; C257-R320 HydrophobicContact CB-CG 4.14Å; C257-C321 VanDerWaalsContact CB-SG 3.59Å; C257-C321 PolarHBondContact N-SG 3.32Å; C257-C321 PolarHBondContact SG-SG 3.15Å
258T56Low48Very low98 Ų9874.6 Ų74.660%0.60140%0.401SS*.Hα-helixtrans-54.9-32-176.3460000114.6I261 A262T258-I261 PolarHBondContact O-N 3.36Å; T258-A262 WeakPolarHBondContact O-CB 3.22Å; T258-A262 PolarHBondContact O-N 3.4Å
259R48.6Very low48.1Very low187 Ų18773.2 Ų73.271%0.70640%0.399SS*.Hα-helixtrans-68.4-37.4176-167.2175-177.9176.9-0.5112.1C257 V263C257-R259 PolarHBondContact O-N 3.17Å; C257-R259 VanDerWaalsContact O-N 3.09Å; R259-V263 WeakPolarHBondContact O-CG2 3.24Å; R259-V263 PolarHBondContact O-N 3.49Å
260C54.7Low48.3Very low29 Ų2971.9 Ų71.920%0.19640%0.398CS..Hα-helixtrans-73.9-36.6175.5-65.80000112.3C257 V263 R264C257-C260 WeakPolarHBondContact O-CB 3.4Å; C257-C260 PolarHBondContact O-N 3.22Å; C260-V263 PolarHBondContact O-N 2.83Å; C260-R264 WeakPolarHBondContact O-CB 3.37Å; C260-R264 PolarHBondContact O-N 3.48Å
261I53.4Low48.3Very low51 Ų5172.4 Ų72.426%0.26240%0.398SS..Hα-helixtrans-59.8-47.5173.5-61.4173.1000110C257 T258 V263 R264 S265C257-I261 PolarHBondContact O-N 2.79Å; T258-I261 PolarHBondContact O-N 3.36Å; I261-V263 PolarHBondContact O-N 2.9Å; I261-R264 PolarHBondContact O-N 3.49Å; I261-S265 WeakPolarHBondContact O-CB 3.46Å; I261-S265 PolarHBondContact O-N 3.19Å; I261-S265 PolarHBondContact O-OG 3.14Å
262A50.2Low48Very low53 Ų5374.3 Ų74.344%0.43843%0.426SS..Hα-helixtrans-56.8-52.4177.400000111.9T258 R264 S265 S266T258-A262 WeakPolarHBondContact O-CB 3.22Å; T258-A262 PolarHBondContact O-N 3.4Å; A262-R264 PolarHBondContact O-N 3.46Å; A262-S265 PolarHBondContact O-N 3.37Å; A262-S265 PolarHBondContact O-OG 2.88Å; A262-S266 PolarHBondContact O-N 2.89Å; A262-S266 VanDerWaalsContact O-N 3.13Å; A262-S266 PolarHBondContact O-OG 3.05Å
263V53.6Low47.5Very low81 Ų8174.5 Ų74.549%0.49144%0.436SS..Hα-helixtrans-61.2-44.4-179.9173.70000112.1R259 C260 I261 S265 S266 I267R259-V263 WeakPolarHBondContact O-CG2 3.24Å; R259-V263 PolarHBondContact O-N 3.49Å; C260-V263 PolarHBondContact O-N 2.83Å; I261-V263 PolarHBondContact O-N 2.9Å; V263-S265 VanDerWaalsContact C-N 3.34Å; V263-S265 PolarHBondContact O-N 3.36Å; V263-S266 WeakPolarHBondContact CA-OG 3.17Å; V263-S266 PolarHBondContact O-N 2.89Å; V263-S266 PolarHBondContact O-OG 2.88Å; V263-I267 HydrophobicContact CG1-CD1 4.09Å; V263-I267 WeakPolarHBondContact O-CG1 3.44Å; V263-I267 PolarHBondContact O-N 3.21Å
264R48.6Very low46.6Very low80 Ų8076.8 Ų76.830%0.30246%0.46SS..Hα-helixtrans-58.9-44.3174.1-82.1177.2153.9169.1-8.6111.8D28 R253 C260 I261 A262 S266 I267 V268D28-R264 IonicContact OD2-NH1 3.26Å; R253-R264 PolarHBondContact O-NH1 3.47Å; R253-R264 VanDerWaalsContact O-NH1 3.14Å; C260-R264 WeakPolarHBondContact O-CB 3.37Å; C260-R264 PolarHBondContact O-N 3.48Å; I261-R264 PolarHBondContact O-N 3.49Å; A262-R264 PolarHBondContact O-N 3.46Å; R264-S266 VanDerWaalsContact C-N 3.28Å; R264-S266 PolarHBondContact O-N 3.23Å; R264-I267 PolarHBondContact O-N 3.27Å; R264-I267 VanDerWaalsContact O-N 3.15Å; R264-V268 PolarHBondContact O-N 3.38Å
265S46.1Very low45.4Very low67 Ų6782.4 Ų82.447%0.46950%0.495SS..Hα-helixtrans-64.7-29.2-179.373.30000113.7I261 A262 V263 L269I261-S265 WeakPolarHBondContact O-CB 3.46Å; I261-S265 PolarHBondContact O-N 3.19Å; I261-S265 PolarHBondContact O-OG 3.14Å; A262-S265 PolarHBondContact O-N 3.37Å; A262-S265 PolarHBondContact O-OG 2.88Å; V263-S265 VanDerWaalsContact C-N 3.34Å; V263-S265 PolarHBondContact O-N 3.36Å; S265-L269 WeakPolarHBondContact O-CD1 3.28Å; S265-L269 WeakPolarHBondContact O-CG 3.35Å
266S46Very low44.2Very low71 Ų7189.3 Ų89.350%0.49753%0.532SS..Hα-helixtrans-75.3-27173.236.50000114.4A262 V263 R264A262-S266 PolarHBondContact O-N 2.89Å; A262-S266 VanDerWaalsContact O-N 3.13Å; A262-S266 PolarHBondContact O-OG 3.05Å; V263-S266 WeakPolarHBondContact CA-OG 3.17Å; V263-S266 PolarHBondContact O-N 2.89Å; V263-S266 PolarHBondContact O-OG 2.88Å; R264-S266 VanDerWaalsContact C-N 3.28Å; R264-S266 PolarHBondContact O-N 3.23Å
267I42.6Very low43.2Very low88 Ų8893 Ų9345%0.45156%0.563SS.*Hα-helixtrans-77.8-44.9-179.1-65.6163.5000110.7V263 R264 L269 A270 E271V263-I267 HydrophobicContact CG1-CD1 4.09Å; V263-I267 WeakPolarHBondContact O-CG1 3.44Å; V263-I267 PolarHBondContact O-N 3.21Å; R264-I267 PolarHBondContact O-N 3.27Å; R264-I267 VanDerWaalsContact O-N 3.15Å; I267-L269 PolarHBondContact O-N 3.29Å; I267-L269 VanDerWaalsContact O-N 3.11Å; I267-A270 WeakPolarHBondContact O-CB 3.45Å; I267-A270 PolarHBondContact O-N 2.88Å; I267-E271 PolarHBondContact O-N 3.41Å
268V42.3Very low42.2Very low105 Ų105100.6 Ų100.664%0.63660%0.604SS**THydrogen-bonded Turntrans-64.1-18.5178.7179.50000112.7R264R264-V268 PolarHBondContact O-N 3.38Å
269L42.4Very low41.3Very low151 Ų151102.1 Ų102.179%0.79161%0.613SS**THydrogen-bonded Turntrans-83.9-12.8172.3-70.6172.9000113.9S265 I267S265-L269 WeakPolarHBondContact O-CD1 3.28Å; S265-L269 WeakPolarHBondContact O-CG 3.35Å; I267-L269 PolarHBondContact O-N 3.29Å; I267-L269 VanDerWaalsContact O-N 3.11Å
270A40.2Very low40.7Very low74 Ų74101.8 Ų101.861%0.61262%0.62SS**THydrogen-bonded Turntrans-93.1-34.917800000112.6I267 G272I267-A270 WeakPolarHBondContact O-CB 3.45Å; I267-A270 PolarHBondContact O-N 2.88Å; A270-G272 PolarHBondContact O-N 3.14Å
271E40.7Very low39.7Very low157 Ų157107.7 Ų107.773%0.73465%0.646SS**THydrogen-bonded Turntrans-75.5-4.7-179.8-62.4176.2144.900113.6I267 G273I267-E271 PolarHBondContact O-N 3.41Å; E271-G273 PolarHBondContact O-N 2.94Å
272G34.5Very low38.8Very low76 Ų76112.2 Ų112.278%0.78467%0.666SS**THydrogen-bonded Turntrans-87.516.6-177.200000116.1A270A270-G272 PolarHBondContact O-N 3.14Å
273G29.2Very low37.8Very low50 Ų50115.1 Ų115.152%0.51568%0.679SS.*SBendtrans-161.8163.1-177.800000114.8E271E271-G273 PolarHBondContact O-N 2.94Å
274T29.2Very low36.9Very low144 Ų144116.9 Ų116.988%0.88370%0.695SS**  trans68.168.5177.960.40000117.5
275T29.2Very low36Very low129 Ų129117.5 Ų117.579%0.79172%0.717SS**  trans-115.2171.9133.151.50000109
276D31.1Very low35.3Very low162 Ų162122.2 Ų122.287%0.86673%0.732SS**  trans67.870.1179.3-54.2-14.3000116.2
277A32Very low34.6Very low93 Ų93123.2 Ų123.277%0.76974%0.739SS**  trans-14590.6162.400000111.5
278N36.5Very low34.2Very low166 Ų166123.6 Ų123.689%0.88875%0.749SS**  trans-158.7108168.3-94.2-35.1000109.8
279T35.8Very low33.9Very low131 Ų131124 Ų12480%0.80476%0.757SS**  trans161.498.9148.5-670000109.5
280E36.6Very low33.5Very low180 Ų180122.2 Ų122.284%0.84176%0.756SS**  trans51.6109.5136.9-60.5176.5179.500122.2
281M34.1Very low33.3Very low153 Ų153124.5 Ų124.575%0.75477%0.765SS**  85.4102.4117.1-149.3158.7-176.100121.9
282E33.6Very low32.9Very low145 Ų145125.8 Ų125.868%0.67877%0.769SS**  trans82.7116133.9-75.5-178.1178.100125.1
283T30Very low32.7Very low115 Ų115129.2 Ų129.271%0.70676%0.764SS**  trans80.3121132.958.80000123.3
284S33.6Very low32.9Very low117 Ų117136.9 Ų136.982%0.81878%0.783SS**  trans66.3165145.5690000119.1
285A31.3Very low32.8Very low93 Ų93134.7 Ų134.777%0.76977%0.774SS**  cis-174.8159-35.700000107.7
286E30.9Very low32.9Very low167 Ų167136.3 Ų136.378%0.7878%0.776SS**  cis-156168.5-7.2-144.2-130.9-94.200111
287S31.7Very low32.6Very low92 Ų92139 Ų13964%0.64377%0.774SS**  trans66.8169.2162.295.10000116.6
288S32.8Very low32.4Very low95 Ų95140.3 Ų140.366%0.66478%0.775SS**  cis-160.5156.2-5.526.10000111.9
289S37.6Very low32Very low115 Ų115143.8 Ų143.880%0.80478%0.775SS**  trans66.2151.9157.173.20000119.8
290S33.4Very low31.6Very low112 Ų112145.4 Ų145.478%0.78378%0.778SS**  cis-159.1169.2-23.359.50000109.8
291P36.4Very low31.4Very low123 Ų123143.7 Ų143.780%0.79977%0.773SS**  trans-120.9165.7-153.742.4-33.5000118.1
292F31.9Very low31Very low184 Ų184141.5 Ų141.581%0.80777%0.77SS**  trans-157.690.1153.7-156.7-102.6000110.5
293E30.9Very low30.6Very low148 Ų148146.7 Ų146.769%0.69278%0.783SS**  83101.685.3-172.9166.7-140.800116.1
294K32.6Very low30.5Very low210 Ų210146 Ų14691%0.91378%0.783SS**  trans-159.8115.3130.8-113.3169.5-173.3173.40110.4
295S26.3Very low30.1Very low98 Ų98148.4 Ų148.469%0.68578%0.783SS**  trans-86.4125.6-172-172.20000112.8
296I31.1Very low29.8Very low163 Ų163149.3 Ų149.384%0.83678%0.784SS**  trans-114.5113.1155.9-62179000106.5
297R26.4Very low29.8Very low219 Ų219146.8 Ų146.883%0.82678%0.78SS**PPolyproline II helixtrans-73.6127.9-178.1-62.1-177.9-177.6-172.20.3110.1R299R297-R299 PolarHBondContact O-N 3.25Å
298P27Very low29.5Very low120 Ų120147.1 Ų147.178%0.77978%0.782SS**PPolyproline II helixtrans-63.5127.6165.927.8-32.6000108.6I300P298-I300 PolarHBondContact O-N 3.15Å
299R27.4Very low29.3Very low239 Ų239147.7 Ų147.790%0.90278%0.778SS**PPolyproline II helixtrans-69124174.8-101.5-177.6171.3169.2-2.5109R297 I301R297-R299 PolarHBondContact O-N 3.25Å; R299-I301 PolarHBondContact O-N 3.35Å
300I28.4Very low28.9Very low166 Ų166147.6 Ų147.685%0.85178%0.784SS**PPolyproline II helixtrans-61.2118.2177.2-62.4169.1000108.6P298P298-I300 PolarHBondContact O-N 3.15Å
301I31.1Very low28.6Very low143 Ų143147.9 Ų147.973%0.73377%0.773SS**PPolyproline II helixtrans-74129.9172.2-59.8173.7000107.8R299 R303R299-I301 PolarHBondContact O-N 3.35Å; I301-R303 PolarHBondContact O-N 3.17Å
302P27.3Very low28.3Very low107 Ų107149.1 Ų149.170%0.69578%0.778SS**PPolyproline II helixtrans-65.5123.5177.626.2-33.3000111S304P302-S304 PolarHBondContact O-N 2.89Å
303R25.3Very low28.3Very low255 Ų255146.3 Ų146.396%0.96277%0.771SS**  trans-76.485.4176.8-75.5178.1164.6146.3-6.7110.9I301I301-R303 PolarHBondContact O-N 3.17Å
304S26.2Very low28.4Very low99 Ų99144 Ų14469%0.69277%0.771SS**  trans-155.451.2174.567.20000115.4P302P302-S304 PolarHBondContact O-N 2.89Å
305M27Very low28.7Very low168 Ų168140.9 Ų140.983%0.82876%0.76SS**  trans-147.593.6152.4-76.9-150.579.800110.1V307M305-V307 HydrophobicContact CB-CG2 4.41Å; M305-V307 HydrophobicContact CE-CG2 4.33Å; M305-V307 PolarHBondContact O-N 3.33Å
306S25Very low29.5Very low113 Ų113139.6 Ų139.679%0.7975%0.751SS**  trans-78.387.916750.50000109.2S308S306-S308 PolarHBondContact O-N 3.33Å
307V29.3Very low30.5Very low113 Ų113138 Ų13869%0.68574%0.744SS**  trans-81.571.4171.8-171.50000108.9M305 N309M305-V307 HydrophobicContact CB-CG2 4.41Å; M305-V307 HydrophobicContact CE-CG2 4.33Å; M305-V307 PolarHBondContact O-N 3.33Å; V307-N309 VanDerWaalsContact C-N 3.27Å; V307-N309 PolarHBondContact O-N 2.82Å; V307-N309 VanDerWaalsContact O-N 3.1Å
308S25.6Very low32.2Very low100 Ų100129.9 Ų129.970%0.69972%0.72SS**  trans-74.286.4160.553.40000108.2S306S306-S308 PolarHBondContact O-N 3.33Å
309N29Very low33.8Very low106 Ų106130.8 Ų130.857%0.56771%0.714SS**  trans-169.2125.6146.3-97.1-5.1000109.8V307 E311V307-N309 VanDerWaalsContact C-N 3.27Å; V307-N309 PolarHBondContact O-N 2.82Å; V307-N309 VanDerWaalsContact O-N 3.1Å; N309-E311 HydrophobicContact CB-CB 4.32Å; N309-E311 HydrophobicContact CB-CG 3.9Å; N309-E311 PolarHBondContact ND2-OE1 3.41Å; N309-E311 PolarHBondContact O-N 3.03Å
310A28.6Very low35.3Very low114 Ų114125.2 Ų125.294%0.94269%0.693SS**  trans-80.154165.800000109.5T312A310-T312 PolarHBondContact O-N 3.11Å
311E28.8Very low36.8Very low117 Ų117118.4 Ų118.455%0.54766%0.66SS.*  trans-73122.5179.4-93165.5-164.900110.4N309 L313N309-E311 HydrophobicContact CB-CB 4.32Å; N309-E311 HydrophobicContact CB-CG 3.9Å; N309-E311 PolarHBondContact ND2-OE1 3.41Å; N309-E311 PolarHBondContact O-N 3.03Å; E311-L313 HydrophobicContact CB-CD1 3.85Å; E311-L313 HydrophobicContact CB-CG 4.11Å; E311-L313 PolarHBondContact O-N 3.13Å
312T28.7Very low38.2Very low149 Ų149116 Ų11691%0.91465%0.651SS**  trans-6482.1167.946.90000110.3A310A310-T312 PolarHBondContact O-N 3.11Å
313L32.3Very low39.7Very low126 Ų126113.9 Ų113.966%0.6663%0.632SS**  trans-96.7104.1-175.3-90.6156.1000111.8E311 E315E311-L313 HydrophobicContact CB-CD1 3.85Å; E311-L313 HydrophobicContact CB-CG 4.11Å; E311-L313 PolarHBondContact O-N 3.13Å; L313-E315 PolarHBondContact O-N 3.4Å
314S32.2Very low41.5Very low98 Ų98103.3 Ų103.369%0.68560%0.596SS**  trans-7.2103.5167.8570000116.1S316S314-S316 PolarHBondContact O-N 3.33Å; S314-S316 VanDerWaalsContact O-N 3.16Å
315E38.9Very low43Very low146 Ų146100 Ų10068%0.68257%0.574SS**  trans-78.75.1-171.2-125.2-152.4119.200115.5R253 L313R253-E315 IonicContact CZ-OE1 3.17Å; R253-E315 IonicContact NH1-OE1 2.79Å; R253-E315 PolarHBondContact NH1-OE1 2.98Å; R253-E315 PolarHBondContact NH2-O 2.92Å; R253-E315 IonicContact NH2-OE1 2.83Å; R253-E315 PolarHBondContact NH2-OE1 3.06Å; L313-E315 PolarHBondContact O-N 3.4Å
316S44.7Very low44.5Very low70 Ų7095.2 Ų95.249%0.4956%0.562SS.*SBendtrans-83.2-55.9-163.853.30000115.1S314S314-S316 PolarHBondContact O-N 3.33Å; S314-S316 VanDerWaalsContact O-N 3.16Å
317D52.3Low46.2Very low130 Ų13096.2 Ų96.270%0.69555%0.548SS*.  trans-116.986.6-153.2-68.2-72.6000115.4H319D317-H319 PolarHBondContact O-N 3.42Å
318C61.6Low47.6Very low48 Ų4890.9 Ų90.932%0.32452%0.516SS..  trans-80.596.4165.2-170.20000111.2R320 C321 V322C318-R320 PolarHBondContact O-N 3.29Å; C318-C321 HydrophobicContact CB-CB 4.2Å; C318-C321 WeakPolarHBondContact O-CB 3.25Å; C318-C321 PolarHBondContact O-N 3.1Å; C318-V322 PolarHBondContact O-N 3.27Å
319H60.5Low49.2Very low140 Ų14090 Ų9065%0.64851%0.508SS*.Hα-helixtrans-43.9-42.8177.2-175.4-78.9000113.6D317 C321 V322 E323D317-H319 PolarHBondContact O-N 3.42Å; H319-C321 VanDerWaalsContact C-N 3.3Å; H319-C321 PolarHBondContact O-N 3.4Å; H319-V322 PolarHBondContact O-N 2.54Å; H319-E323 WeakPolarHBondContact O-CB 3.41Å; H319-E323 PolarHBondContact O-N 3.02Å
320R59.5Low50.5Low122 Ų12295.9 Ų95.946%0.4652%0.522SS..Hα-helixtrans-69.4-23.5-178.6-159.7174.3-170.4173.13.8113.4C257 C318 T324C257-R320 HydrophobicContact CB-CB 4.3Å; C257-R320 HydrophobicContact CB-CG 4.14Å; C318-R320 PolarHBondContact O-N 3.29Å; R320-T324 VanDerWaalsContact O-CB 3.28Å; R320-T324 WeakPolarHBondContact O-CB 3.45Å; R320-T324 PolarHBondContact O-N 3.19Å; R320-T324 VanDerWaalsContact O-N 3.11Å; R320-T324 PolarHBondContact O-OG1 2.82Å
321C59.8Low52Low23 Ų2395.7 Ų95.716%0.15550%0.5CS..Hα-helixtrans-78-48172-65.20000110.9C257 C318 H319 E323 T324 A325C257-C321 VanDerWaalsContact CB-SG 3.59Å; C257-C321 PolarHBondContact N-SG 3.32Å; C257-C321 PolarHBondContact SG-SG 3.15Å; C318-C321 HydrophobicContact CB-CB 4.2Å; C318-C321 WeakPolarHBondContact O-CB 3.25Å; C318-C321 PolarHBondContact O-N 3.1Å; H319-C321 VanDerWaalsContact C-N 3.3Å; H319-C321 PolarHBondContact O-N 3.4Å; C321-E323 VanDerWaalsContact C-N 3.31Å; C321-E323 PolarHBondContact O-N 3.29Å; C321-T324 PolarHBondContact O-N 2.99Å; C321-T324 VanDerWaalsContact O-N 3.08Å; C321-A325 PolarHBondContact O-N 2.69Å
322V58.7Low53.8Low91 Ų9191.1 Ų91.155%0.55248%0.484SS*.Hα-helixtrans-56.4-46.6175179.90000110.7C318 H319 T324 A325 A326C318-V322 PolarHBondContact O-N 3.27Å; H319-V322 PolarHBondContact O-N 2.54Å; V322-T324 PolarHBondContact O-N 2.9Å; V322-A325 WeakPolarHBondContact O-CB 3.36Å; V322-A325 PolarHBondContact O-N 3.11Å; V322-A326 PolarHBondContact O-N 2.87Å
323E60.2Low56.1Low64 Ų6484.6 Ų84.630%0.29944%0.443SS..Hα-helixtrans-65.7-36.4176.1-178.7175.3-135.600112.6H319 C321 A325 A326 R327H319-E323 WeakPolarHBondContact O-CB 3.41Å; H319-E323 PolarHBondContact O-N 3.02Å; C321-E323 VanDerWaalsContact C-N 3.31Å; C321-E323 PolarHBondContact O-N 3.29Å; E323-A325 VanDerWaalsContact C-N 3.34Å; E323-A326 PolarHBondContact O-N 3.03Å; E323-R327 VanDerWaalsContact CD-CZ 3.44Å; E323-R327 HydrophobicContact CG-CG 4.23Å; E323-R327 VanDerWaalsContact CG-NE 3.27Å; E323-R327 VanDerWaalsContact O-CB 3.27Å; E323-R327 WeakPolarHBondContact O-CB 3.06Å; E323-R327 WeakPolarHBondContact O-CG 3.07Å; E323-R327 PolarHBondContact O-N 2.8Å; E323-R327 IonicContact OE1-CZ 2.95Å; E323-R327 VanDerWaalsContact OE1-CZ 3.24Å; E323-R327 IonicContact OE1-NE 2.76Å; E323-R327 PolarHBondContact OE1-NE 3.38Å; E323-R327 IonicContact OE1-NH2 3.36Å; E323-R327 PolarHBondContact OE1-NH2 3.3Å; E323-R327 IonicContact OE2-CZ 3.04Å; E323-R327 IonicContact OE2-NH2 3.17Å
324T62Low58.3Low33 Ų3380.1 Ų80.120%0.20242%0.422CS..Hα-helixtrans-64.9-40.1174.5-64.60000111.2I255 R320 C321 V322 R327 A328I255-T324 HydrophobicContact CG2-CG2 3.92Å; R320-T324 VanDerWaalsContact O-CB 3.28Å; R320-T324 WeakPolarHBondContact O-CB 3.45Å; R320-T324 PolarHBondContact O-N 3.19Å; R320-T324 VanDerWaalsContact O-N 3.11Å; R320-T324 PolarHBondContact O-OG1 2.82Å; C321-T324 PolarHBondContact O-N 2.99Å; C321-T324 VanDerWaalsContact O-N 3.08Å; V322-T324 PolarHBondContact O-N 2.9Å; T324-R327 PolarHBondContact O-N 3.07Å; T324-A328 WeakPolarHBondContact O-CB 3.19Å; T324-A328 PolarHBondContact O-N 2.96Å
325A58.5Low60.6Low28 Ų2884.9 Ų84.923%0.23143%0.425CS..Hα-helixtrans-63.2-48.2173.800000111.6I255 C321 V322 E323 R327 A328 P329I255-A325 HydrophobicContact CD1-CB 3.58Å; I255-A325 HydrophobicContact CG2-CB 4.32Å; C321-A325 PolarHBondContact O-N 2.69Å; V322-A325 WeakPolarHBondContact O-CB 3.36Å; V322-A325 PolarHBondContact O-N 3.11Å; E323-A325 VanDerWaalsContact C-N 3.34Å; A325-R327 VanDerWaalsContact C-N 3.29Å; A325-R327 PolarHBondContact O-N 2.96Å; A325-A328 WeakPolarHBondContact O-CB 3.45Å; A325-A328 PolarHBondContact O-N 2.88Å; A325-A328 VanDerWaalsContact O-N 3.14Å; A325-P329 WeakPolarHBondContact O-CD 3.5Å
326A57.7Low62.5Low69 Ų6982 Ų8257%0.5741%0.413SS*.Hα-helixtrans-63.3-32177.500000113.4V322 E323V322-A326 PolarHBondContact O-N 2.87Å; E323-A326 PolarHBondContact O-N 3.03Å
327R60.9Low64.1Low134 Ų13478.8 Ų78.851%0.50639%0.391SS..Hα-helixtrans-81-19.1175.3-69.9172.9-178.8-159.83.8113.3E323 T324 A325 R330E323-R327 VanDerWaalsContact CD-CZ 3.44Å; E323-R327 HydrophobicContact CG-CG 4.23Å; E323-R327 VanDerWaalsContact CG-NE 3.27Å; E323-R327 VanDerWaalsContact O-CB 3.27Å; E323-R327 WeakPolarHBondContact O-CB 3.06Å; E323-R327 WeakPolarHBondContact O-CG 3.07Å; E323-R327 PolarHBondContact O-N 2.8Å; E323-R327 IonicContact OE1-CZ 2.95Å; E323-R327 VanDerWaalsContact OE1-CZ 3.24Å; E323-R327 IonicContact OE1-NE 2.76Å; E323-R327 PolarHBondContact OE1-NE 3.38Å; E323-R327 IonicContact OE1-NH2 3.36Å; E323-R327 PolarHBondContact OE1-NH2 3.3Å; E323-R327 IonicContact OE2-CZ 3.04Å; E323-R327 IonicContact OE2-NH2 3.17Å; T324-R327 PolarHBondContact O-N 3.07Å; A325-R327 VanDerWaalsContact C-N 3.29Å; A325-R327 PolarHBondContact O-N 2.96Å; R327-R330 PolarHBondContact O-N 2.85Å; R327-R330 VanDerWaalsContact O-N 3.15Å
328A59Low65.6Low1 Ų178.3 Ų78.31%0.00838%0.379CS..Hα-helixtrans-58.8-47.8-172.200000114.1Y25 L237 T324 A325 R330 K331Y25-A328 HydrophobicContact CD1-CB 3.86Å; Y25-A328 HydrophobicContact CE1-CB 3.28Å; L237-A328 HydrophobicContact CD1-CB 3.84Å; L237-A328 HydrophobicContact CD2-CB 3.75Å; L237-A328 HydrophobicContact CG-CB 4.42Å; T324-A328 WeakPolarHBondContact O-CB 3.19Å; T324-A328 PolarHBondContact O-N 2.96Å; A325-A328 WeakPolarHBondContact O-CB 3.45Å; A325-A328 PolarHBondContact O-N 2.88Å; A325-A328 VanDerWaalsContact O-N 3.14Å; A328-R330 PolarHBondContact O-N 3.26Å; A328-K331 PolarHBondContact O-N 2.72Å; A328-K331 VanDerWaalsContact O-N 3.15Å
329P58.8Low66.6Low81 Ų8184.4 Ų84.453%0.52640%0.395SS..Hα-helixtrans-60.4-29.9177.9-23.735.1000113.2A325 K331A325-P329 WeakPolarHBondContact O-CD 3.5Å; P329-K331 VanDerWaalsContact C-N 3.33Å; P329-K331 PolarHBondContact O-N 3.37Å
330R56.7Low67.5Low230 Ų23078.4 Ų78.487%0.86837%0.369SS*.Hα-helixtrans-75.4-17-178.6-59.6-174.2-178.3-175.90.8113.7R327 A328R327-R330 PolarHBondContact O-N 2.85Å; R327-R330 VanDerWaalsContact O-N 3.15Å; A328-R330 PolarHBondContact O-N 3.26Å
331K60Low68.5Low110 Ų11072.8 Ų72.848%0.47835%0.348SS..Hα-helixtrans-80.5-29.5177.3-72.6175.7170.9-176.10112.9Y25 A328 P329Y25-K331 VanDerWaalsContact OH-CD 3.24Å; Y25-K331 WeakPolarHBondContact OH-CD 3.31Å; A328-K331 PolarHBondContact O-N 2.72Å; A328-K331 VanDerWaalsContact O-N 3.15Å; P329-K331 VanDerWaalsContact C-N 3.33Å; P329-K331 PolarHBondContact O-N 3.37Å
332G66.9Low69.5Low20 Ų2074.5 Ų74.521%0.20636%0.364CS..  trans61.4-170.2-173.900000113.6F233F233-G332 WeakPolarHBondContact CE1-O 3.44Å; F233-G332 WeakPolarHBondContact CZ-O 3.44Å
333L76Confident70.7Confident12 Ų1275.1 Ų75.16%0.06336%0.364CS..SBendtrans-53.5143.2-177.8-74.6170000113.2C229 R230 F233 R338 L341C229-L333 HydrophobicContact CB-CD1 4.05Å; R230-L333 HydrophobicContact CB-CD1 4.07Å; R230-L333 HydrophobicContact CB-CG 4.34Å; F233-L333 HydrophobicContact CB-CD2 3.68Å; F233-L333 HydrophobicContact CD2-CD2 3.99Å; F233-L333 HydrophobicContact CG-CD2 3.85Å; L333-R338 PolarHBondContact O-NE 3.03Å; L333-R338 PolarHBondContact O-NH2 3.28Å; L333-L341 HydrophobicContact CD1-CD1 3.75Å
334P78.9Confident71.5Confident32 Ų3272.4 Ų72.421%0.20835%0.353CS..  trans-52.7142.8178.3-27.534.1000112.6A20 F233 I336 V337 R338A20-P334 HydrophobicContact CB-CG 4.02Å; F233-P334 HydrophobicContact CE2-CG 4.21Å; P334-I336 PolarHBondContact O-N 2.93Å; P334-V337 PolarHBondContact O-N 2.76Å; P334-V337 VanDerWaalsContact O-N 3.1Å; P334-R338 WeakPolarHBondContact O-CB 3.47Å; P334-R338 PolarHBondContact O-N 2.91Å
335R81.4Confident72.2Confident199 Ų19971.3 Ų71.375%0.75135%0.347SS*.Hα-helixtrans-50.9-33.5-177.5-69.5-176.3176.6-169.3-1.3113.4R339R335-R339 WeakPolarHBondContact O-CG 3.29Å; R335-R339 PolarHBondContact O-N 3.06Å
336I79.2Confident73.2Confident84 Ų8472.2 Ų72.243%0.43135%0.354SS..Hα-helixtrans-68-55.3178.9-72.4169.1000111.4P334 R338 R339 S340P334-I336 PolarHBondContact O-N 2.93Å; I336-R338 VanDerWaalsContact C-N 3.31Å; I336-R338 PolarHBondContact O-N 2.86Å; I336-R339 PolarHBondContact O-N 3.28Å; I336-S340 PolarHBondContact O-N 3.29Å; I336-S340 PolarHBondContact O-OG 3.48Å
337V76.8Confident74Confident3 Ų375.3 Ų75.32%0.01835%0.354CS..Hα-helixtrans-62.4-39.9178.8178.50000111.1V16 L53 C57 P334 R339 S340 L341V16-V337 HydrophobicContact CG1-CG1 4.26Å; L53-V337 HydrophobicContact CB-CG2 4.12Å; C57-V337 HydrophobicContact CB-CG1 4.28Å; P334-V337 PolarHBondContact O-N 2.76Å; P334-V337 VanDerWaalsContact O-N 3.1Å; V337-R339 VanDerWaalsContact C-N 3.34Å; V337-R339 PolarHBondContact O-N 3.21Å; V337-S340 PolarHBondContact O-N 2.69Å; V337-L341 HydrophobicContact CG1-CD1 4.04Å; V337-L341 WeakPolarHBondContact O-CG 3.42Å; V337-L341 PolarHBondContact O-N 2.78Å; V337-L341 VanDerWaalsContact O-N 3.13Å
338R83.9Confident74.4Confident120 Ų12069 Ų6945%0.45333%0.331SS..Hα-helixtrans-63.5-34.7179.3-162.9-163.2-47.2170.3-1.3113.4L333 P334 I336 A342L333-R338 PolarHBondContact O-NE 3.03Å; L333-R338 PolarHBondContact O-NH2 3.28Å; P334-R338 WeakPolarHBondContact O-CB 3.47Å; P334-R338 PolarHBondContact O-N 2.91Å; I336-R338 VanDerWaalsContact C-N 3.31Å; I336-R338 PolarHBondContact O-N 2.86Å; R338-A342 WeakPolarHBondContact O-CB 3.48Å; R338-A342 PolarHBondContact O-N 3Å; R338-A342 VanDerWaalsContact O-N 3.11Å
339R83.8Confident74.9Confident176 Ų17673.7 Ų73.766%0.66435%0.351SS*.Hα-helixtrans-63.9-54.7173.3-80.4172.2175.9-177-3.8110.2R335 I336 V337 L341 A342 D343R335-R339 WeakPolarHBondContact O-CG 3.29Å; R335-R339 PolarHBondContact O-N 3.06Å; I336-R339 PolarHBondContact O-N 3.28Å; V337-R339 VanDerWaalsContact C-N 3.34Å; V337-R339 PolarHBondContact O-N 3.21Å; R339-L341 PolarHBondContact O-N 2.98Å; R339-L341 VanDerWaalsContact O-N 3.11Å; R339-A342 CarbonylContact O-C 3.58Å; R339-A342 WeakPolarHBondContact O-CA 3.32Å; R339-A342 WeakPolarHBondContact O-CB 3.37Å; R339-A342 PolarHBondContact O-N 2.86Å; R339-D343 VanDerWaalsContact C-OD2 3.26Å; R339-D343 PolarHBondContact O-N 2.65Å
340S78.9Confident75.4Confident14 Ų1475.5 Ų75.510%0.09836%0.356CS..Hα-helixtrans-51.7-39.6178.6-48.30000113.4G54 L61 I336 V337 A344G54-S340 PolarHBondContact O-OG 2.83Å; L61-S340 WeakPolarHBondContact CD1-O 3.26Å; I336-S340 PolarHBondContact O-N 3.29Å; I336-S340 PolarHBondContact O-OG 3.48Å; V337-S340 PolarHBondContact O-N 2.69Å; S340-A344 VanDerWaalsContact O-CB 3.31Å; S340-A344 WeakPolarHBondContact O-CB 3.31Å; S340-A344 PolarHBondContact O-N 3.18Å; S340-A344 VanDerWaalsContact O-N 3.08Å
341L80.8Confident75.7Confident5 Ų567.1 Ų67.13%0.02633%0.327CS..Hα-helixtrans-66.9-45.1173.9-72.5162.7000113.1I13 L61 C229 L333 V337 R339 S345I13-L341 HydrophobicContact CD1-CD2 4.41Å; L61-L341 HydrophobicContact CD1-CD2 3.81Å; L61-L341 HydrophobicContact CD1-CG 4.26Å; L61-L341 HydrophobicContact CD2-CD2 4.08Å; L61-L341 HydrophobicContact CG-CD2 4.49Å; C229-L341 HydrophobicContact CB-CD1 4.08Å; L333-L341 HydrophobicContact CD1-CD1 3.75Å; V337-L341 HydrophobicContact CG1-CD1 4.04Å; V337-L341 WeakPolarHBondContact O-CG 3.42Å; V337-L341 PolarHBondContact O-N 2.78Å; V337-L341 VanDerWaalsContact O-N 3.13Å; R339-L341 PolarHBondContact O-N 2.98Å; R339-L341 VanDerWaalsContact O-N 3.11Å; L341-S345 WeakPolarHBondContact O-CB 3.45Å; L341-S345 PolarHBondContact O-N 3.07Å
342A81.5Confident75.7Confident58 Ų5863 Ų6348%0.47931%0.309SS..Hα-helixtrans-65.8-42177.100000112.3R338 R339 S345 A346R338-A342 WeakPolarHBondContact O-CB 3.48Å; R338-A342 PolarHBondContact O-N 3Å; R338-A342 VanDerWaalsContact O-N 3.11Å; R339-A342 CarbonylContact O-C 3.58Å; R339-A342 WeakPolarHBondContact O-CA 3.32Å; R339-A342 WeakPolarHBondContact O-CB 3.37Å; R339-A342 PolarHBondContact O-N 2.86Å; A342-S345 WeakPolarHBondContact O-CB 3.46Å; A342-S345 PolarHBondContact O-N 3.14Å; A342-A346 WeakPolarHBondContact O-CB 3.47Å; A342-A346 PolarHBondContact O-N 3.36Å
343D82.4Confident75.1Confident104 Ų10465.4 Ų65.456%0.55632%0.323SS*.Hα-helixtrans-65.2-41.5179.4-59.6-34.7000110.9R339 K347R339-D343 VanDerWaalsContact C-OD2 3.26Å; R339-D343 PolarHBondContact O-N 2.65Å; D343-K347 VanDerWaalsContact O-CB 3.22Å; D343-K347 WeakPolarHBondContact O-CB 3.48Å; D343-K347 PolarHBondContact O-N 2.99Å
344A78Confident73.8Confident8 Ų872.4 Ų72.47%0.06635%0.353CS..Hα-helixtrans-63.9-42.6172.600000112.6L61 I65 P222 S340 K347 E348L61-A344 HydrophobicContact CB-CB 3.77Å; L61-A344 HydrophobicContact CD1-CB 3.71Å; L61-A344 HydrophobicContact CD2-CB 4.17Å; L61-A344 HydrophobicContact CG-CB 4.09Å; I65-A344 HydrophobicContact CD1-CB 4.09Å; P222-A344 HydrophobicContact CB-CB 4.24Å; P222-A344 HydrophobicContact CG-CB 4.49Å; S340-A344 VanDerWaalsContact O-CB 3.31Å; S340-A344 WeakPolarHBondContact O-CB 3.31Å; S340-A344 PolarHBondContact O-N 3.18Å; S340-A344 VanDerWaalsContact O-N 3.08Å; A344-K347 PolarHBondContact O-N 2.86Å; A344-E348 PolarHBondContact O-N 3.4Å
345S76.7Confident72.5Confident10 Ų1076.1 Ų76.17%0.0737%0.366CS..Hα-helixtrans-62.4-45.4176.3-176.50000112.2D223 L341 A342 E348 K349D223-S345 WeakPolarHBondContact OD1-CB 3.22Å; D223-S345 PolarHBondContact OD1-OG 3.37Å; L341-S345 WeakPolarHBondContact O-CB 3.45Å; L341-S345 PolarHBondContact O-N 3.07Å; A342-S345 WeakPolarHBondContact O-CB 3.46Å; A342-S345 PolarHBondContact O-N 3.14Å; S345-E348 PolarHBondContact O-N 2.77Å; S345-K349 WeakPolarHBondContact O-CB 3.3Å; S345-K349 WeakPolarHBondContact O-CD 3.23Å; S345-K349 VanDerWaalsContact O-CG 3.3Å; S345-K349 WeakPolarHBondContact O-CG 3.46Å; S345-K349 PolarHBondContact O-N 3.46Å; S345-K349 PolarHBondContact OG-NZ 2.89Å
346A78.3Confident71.2Confident46 Ų4671.7 Ų71.738%0.3835%0.353SS..Hα-helixtrans-62.9-41.9174.400000111.9A342 K349 N350A342-A346 WeakPolarHBondContact O-CB 3.47Å; A342-A346 PolarHBondContact O-N 3.36Å; A346-K349 PolarHBondContact O-N 3.35Å; A346-N350 VanDerWaalsContact O-CB 3.3Å; A346-N350 WeakPolarHBondContact O-CB 3.12Å; A346-N350 PolarHBondContact O-N 3.2Å; A346-N350 PolarHBondContact O-ND2 3.04Å
347K74.7Confident69.9Low135 Ų13572.2 Ų72.259%0.58736%0.364SS*.Hα-helixtrans-63.7-43.8177.5-172.6171.4-175.5171.70112.4D343 A344 M351D343-K347 VanDerWaalsContact O-CB 3.22Å; D343-K347 WeakPolarHBondContact O-CB 3.48Å; D343-K347 PolarHBondContact O-N 2.99Å; A344-K347 PolarHBondContact O-N 2.86Å; K347-M351 WeakPolarHBondContact O-CB 3.24Å; K347-M351 PolarHBondContact O-N 2.91Å
348E69.7Low68.8Low2 Ų274 Ų741%0.00938%0.376CS..Hα-helixtrans-67.6-44.4177.4-169.7163.814000111.6R68 H221 P222 A344 S345 M351 F352R68-E348 IonicContact CZ-OE1 3.29Å; R68-E348 IonicContact NE-OE1 2.89Å; R68-E348 PolarHBondContact NE-OE1 3.19Å; R68-E348 IonicContact NE-OE2 2.76Å; R68-E348 PolarHBondContact NE-OE2 3.34Å; R68-E348 VanDerWaalsContact NE-OE2 3.09Å; R68-E348 IonicContact NH2-OE1 2.64Å; R68-E348 PolarHBondContact NH2-OE1 3.3Å; H221-E348 IonicContact CD2-OE1 2.77Å; H221-E348 PolarHBondContact CD2-OE1 3.39Å; H221-E348 IonicContact NE2-OE1 3.87Å; P222-E348 VanDerWaalsContact CD-CD 3.47Å; P222-E348 WeakPolarHBondContact CD-OE2 3.36Å; P222-E348 HydrophobicContact CG-CB 4.13Å; P222-E348 WeakPolarHBondContact CG-OE2 3.35Å; A344-E348 PolarHBondContact O-N 3.4Å; S345-E348 PolarHBondContact O-N 2.77Å; E348-M351 PolarHBondContact O-N 3.16Å; E348-F352 HydrophobicContact CG-CD2 3.43Å; E348-F352 VanDerWaalsContact CG-CD2 3.43Å; E348-F352 HydrophobicContact CG-CE2 3.58Å; E348-F352 PolarHBondContact O-N 3.21Å
349K70.8Confident67.3Low99 Ų9977.2 Ų77.243%0.4339%0.394SS..Hα-helixtrans-59.7-47.9175.8-76164.6179.6151.70112.2D223 S345 A346 S353D223-K349 IonicContact OD1-NZ 3.67Å; D223-K349 PolarHBondContact OD1-NZ 3.46Å; D223-K349 WeakPolarHBondContact OD2-CE 3.49Å; D223-K349 IonicContact OD2-NZ 2.69Å; D223-K349 PolarHBondContact OD2-NZ 2.91Å; S345-K349 WeakPolarHBondContact O-CB 3.3Å; S345-K349 WeakPolarHBondContact O-CD 3.23Å; S345-K349 VanDerWaalsContact O-CG 3.3Å; S345-K349 WeakPolarHBondContact O-CG 3.46Å; S345-K349 PolarHBondContact O-N 3.46Å; S345-K349 PolarHBondContact OG-NZ 2.89Å; A346-K349 PolarHBondContact O-N 3.35Å; K349-S353 VanDerWaalsContact O-CB 3.24Å; K349-S353 WeakPolarHBondContact O-CB 3.19Å; K349-S353 PolarHBondContact O-N 3.37Å
350N68.8Low66.1Low119 Ų11974.7 Ų74.764%0.63639%0.393SS*.Hα-helixtrans-60.6-50.9176.8-73.5-12.9000111.2A346 F352 S353A346-N350 VanDerWaalsContact O-CB 3.3Å; A346-N350 WeakPolarHBondContact O-CB 3.12Å; A346-N350 PolarHBondContact O-N 3.2Å; A346-N350 PolarHBondContact O-ND2 3.04Å; N350-F352 PolarHBondContact O-N 3.3Å; N350-S353 PolarHBondContact O-N 3.06Å; N350-S353 PolarHBondContact O-OG 2.9Å
351M62.2Low65Low53 Ų5378 Ų7826%0.26140%0.404SS..Hα-helixtrans-60.8-46.8-176.8-178.1-178.870.400112.8I65 Q69 K347 E348 F355I65-M351 HydrophobicContact CG2-CE 3.86Å; I65-M351 HydrophobicContact CG2-SD 4.47Å; Q69-M351 HydrophobicContact CG-CE 3.62Å; Q69-M351 HydrophobicContact CG-SD 3.81Å; Q69-M351 PolarHBondContact NE2-SD 3.36Å; K347-M351 WeakPolarHBondContact O-CB 3.24Å; K347-M351 PolarHBondContact O-N 2.91Å; E348-M351 PolarHBondContact O-N 3.16Å; M351-F355 WeakPolarHBondContact O-CD2 3.12Å
352F60.7Low63.6Low23 Ų2381.3 Ų81.310%0.10142%0.424CS..Hα-helixtrans-88.2-10.8-178.1-70.1-70.8000114.6E348 N350 F354 F355 F356E348-F352 HydrophobicContact CG-CD2 3.43Å; E348-F352 VanDerWaalsContact CG-CD2 3.43Å; E348-F352 HydrophobicContact CG-CE2 3.58Å; E348-F352 PolarHBondContact O-N 3.21Å; N350-F352 PolarHBondContact O-N 3.3Å; F352-F354 PolarHBondContact O-N 2.95Å; F352-F355 HydrophobicContact CD1-CB 4.43Å; F352-F355 PolarHBondContact O-N 3.33Å; F352-F356 HydrophobicContact CB-CD2 3.41Å; F352-F356 VanDerWaalsContact CB-CD2 3.41Å; F352-F356 HydrophobicContact CB-CE2 3.39Å; F352-F356 HydrophobicContact CB-CG 4.35Å; F352-F356 HydrophobicContact CB-CZ 4.33Å; F352-F356 HydrophobicContact CD1-CE2 4.21Å; F352-F356 HydrophobicContact CD1-CZ 4.37Å; F352-F356 HydrophobicContact CD2-CE2 4.19Å; F352-F356 HydrophobicContact CG-CD2 4.23Å; F352-F356 AromaticContact CG-CE2 3.73Å; F352-F356 HydrophobicContact CG-CE2 3.73Å; F352-F356 HydrophobicContact CG-CZ 4.29Å; F352-F356 PolarHBondContact O-N 3.46Å
353S52.9Low62.5Low71 Ų7182.4 Ų82.450%0.49743%0.425SS..Hα-helixtrans-51.9-41.3176.864.50000112.7K349 N350 S357K349-S353 VanDerWaalsContact O-CB 3.24Å; K349-S353 WeakPolarHBondContact O-CB 3.19Å; K349-S353 PolarHBondContact O-N 3.37Å; N350-S353 PolarHBondContact O-N 3.06Å; N350-S353 PolarHBondContact O-OG 2.9Å; S353-S357 VanDerWaalsContact O-CB 3.23Å; S353-S357 WeakPolarHBondContact O-CB 3.39Å; S353-S357 PolarHBondContact O-N 3.01Å; S353-S357 PolarHBondContact O-OG 3.27Å
354F50.1Low61.1Low159 Ų15982.9 Ų82.970%0.69743%0.425SS*.Hα-helixtrans-69.3-38.5176.5-174.4-100.8000113F352 S357F352-F354 PolarHBondContact O-N 2.95Å; F354-S357 PolarHBondContact O-OG 3.29Å
355F52Low59.6Low110 Ų11090.2 Ų90.248%0.48245%0.451SS..Hα-helixtrans-75.3-55.6-180-70.4-81.6000111.8M351 F352 S357 S358 Y361M351-F355 WeakPolarHBondContact O-CD2 3.12Å; F352-F355 HydrophobicContact CD1-CB 4.43Å; F352-F355 PolarHBondContact O-N 3.33Å; F355-S357 VanDerWaalsContact C-N 3.31Å; F355-S357 PolarHBondContact O-N 3.31Å; F355-S358 WeakPolarHBondContact O-CB 3.3Å; F355-S358 PolarHBondContact O-N 3.41Å; F355-S358 VanDerWaalsContact O-N 3.13Å; F355-S358 PolarHBondContact O-OG 3.14Å; F355-Y361 HydrophobicContact CB-CD2 4.35Å; F355-Y361 WeakPolarHBondContact O-CB 3.29Å
356F52.1Low58.6Low106 Ų10697.7 Ų97.747%0.46548%0.479SS..Hα-helixtrans-65.1-27.5-176.8-72.1-49000114.1F352 S358 Y361F352-F356 HydrophobicContact CB-CD2 3.41Å; F352-F356 VanDerWaalsContact CB-CD2 3.41Å; F352-F356 HydrophobicContact CB-CE2 3.39Å; F352-F356 HydrophobicContact CB-CG 4.35Å; F352-F356 HydrophobicContact CB-CZ 4.33Å; F352-F356 HydrophobicContact CD1-CE2 4.21Å; F352-F356 HydrophobicContact CD1-CZ 4.37Å; F352-F356 HydrophobicContact CD2-CE2 4.19Å; F352-F356 HydrophobicContact CG-CD2 4.23Å; F352-F356 AromaticContact CG-CE2 3.73Å; F352-F356 HydrophobicContact CG-CE2 3.73Å; F352-F356 HydrophobicContact CG-CZ 4.29Å; F352-F356 PolarHBondContact O-N 3.46Å; F356-S358 VanDerWaalsContact C-N 3.25Å; F356-S358 PolarHBondContact O-N 2.92Å; F356-Y361 AromaticContact CD1-CD1 3.68Å; F356-Y361 HydrophobicContact CD1-CD1 3.68Å; F356-Y361 AromaticContact CD1-CE1 3.42Å; F356-Y361 HydrophobicContact CD1-CE1 3.42Å; F356-Y361 VanDerWaalsContact CD1-CE1 3.42Å; F356-Y361 HydrophobicContact CD1-CE2 4.37Å; F356-Y361 HydrophobicContact CD1-CG 4.29Å; F356-Y361 AromaticContact CD1-CZ 3.82Å; F356-Y361 HydrophobicContact CE1-CD1 4.17Å; F356-Y361 AromaticContact CE1-CE1 3.43Å; F356-Y361 HydrophobicContact CE1-CE1 3.43Å; F356-Y361 VanDerWaalsContact CE1-CE1 3.43Å; F356-Y361 HydrophobicContact CE1-CE2 4.22Å; F356-Y361 AromaticContact CE1-CZ 3.47Å; F356-Y361 VanDerWaalsContact CE1-CZ 3.47Å
357S52.1Low57.3Low96 Ų96100.6 Ų100.667%0.67149%0.487SS*.THydrogen-bonded Turntrans-73.8-16.4176.359.30000113.4S353 F354 F355S353-S357 VanDerWaalsContact O-CB 3.23Å; S353-S357 WeakPolarHBondContact O-CB 3.39Å; S353-S357 PolarHBondContact O-N 3.01Å; S353-S357 PolarHBondContact O-OG 3.27Å; F354-S357 PolarHBondContact O-OG 3.29Å; F355-S357 VanDerWaalsContact C-N 3.31Å; F355-S357 PolarHBondContact O-N 3.31Å
358S54.8Low56.1Low39 Ų3997.9 Ų97.927%0.27349%0.486SS..SBendtrans-76.8129.8177.2770000111.3F355 F356 L360 Y361F355-S358 WeakPolarHBondContact O-CB 3.3Å; F355-S358 PolarHBondContact O-N 3.41Å; F355-S358 VanDerWaalsContact O-N 3.13Å; F355-S358 PolarHBondContact O-OG 3.14Å; F356-S358 VanDerWaalsContact C-N 3.25Å; F356-S358 PolarHBondContact O-N 2.92Å; S358-L360 PolarHBondContact O-N 2.84Å; S358-L360 VanDerWaalsContact O-N 3.11Å; S358-Y361 PolarHBondContact O-N 2.95Å; S358-Y361 WeakPolarHBondContact OG-CB 3.42Å; S358-Y361 PolarHBondContact OG-N 2.89Å
359K51.8Low55.1Low188 Ų188102 Ų10282%0.81751%0.507SS*.Hα-helixtrans-56.4-25.5167.2-69.5-175.1177.1-178.10112T362 V363K359-T362 PolarHBondContact O-N 3.19Å; K359-V363 PolarHBondContact O-N 3.12Å
360L59.3Low53.8Low124 Ų124102 Ų10265%0.64952%0.518SS*.Hα-helixtrans-61.4-43.2175-169.568.6000111.9S358 T362 V363 M364S358-L360 PolarHBondContact O-N 2.84Å; S358-L360 VanDerWaalsContact O-N 3.11Å; L360-T362 VanDerWaalsContact C-N 3.35Å; L360-T362 PolarHBondContact O-N 2.7Å; L360-V363 PolarHBondContact O-N 3.29Å; L360-M364 HydrophobicContact CG-CG 4.4Å; L360-M364 WeakPolarHBondContact O-CB 3.43Å; L360-M364 VanDerWaalsContact O-CG 3.23Å; L360-M364 WeakPolarHBondContact O-CG 3.44Å; L360-M364 PolarHBondContact O-N 3.45Å
361Y56Low52.8Low83 Ų83107.9 Ų107.933%0.32553%0.531SS..Hα-helixtrans-62.6-40.9177.5-178.5-84000112F355 F356 S358 V363 M364 R365F355-Y361 HydrophobicContact CB-CD2 4.35Å; F355-Y361 WeakPolarHBondContact O-CB 3.29Å; F356-Y361 AromaticContact CD1-CD1 3.68Å; F356-Y361 HydrophobicContact CD1-CD1 3.68Å; F356-Y361 AromaticContact CD1-CE1 3.42Å; F356-Y361 HydrophobicContact CD1-CE1 3.42Å; F356-Y361 VanDerWaalsContact CD1-CE1 3.42Å; F356-Y361 HydrophobicContact CD1-CE2 4.37Å; F356-Y361 HydrophobicContact CD1-CG 4.29Å; F356-Y361 AromaticContact CD1-CZ 3.82Å; F356-Y361 HydrophobicContact CE1-CD1 4.17Å; F356-Y361 AromaticContact CE1-CE1 3.43Å; F356-Y361 HydrophobicContact CE1-CE1 3.43Å; F356-Y361 VanDerWaalsContact CE1-CE1 3.43Å; F356-Y361 HydrophobicContact CE1-CE2 4.22Å; F356-Y361 AromaticContact CE1-CZ 3.47Å; F356-Y361 VanDerWaalsContact CE1-CZ 3.47Å; S358-Y361 PolarHBondContact O-N 2.95Å; S358-Y361 WeakPolarHBondContact OG-CB 3.42Å; S358-Y361 PolarHBondContact OG-N 2.89Å; Y361-V363 VanDerWaalsContact C-N 3.32Å; Y361-V363 PolarHBondContact O-N 2.67Å; Y361-M364 PolarHBondContact O-N 3.16Å; Y361-R365 HydrophobicContact CE1-CB 4.34Å; Y361-R365 WeakPolarHBondContact O-CB 3.32Å; Y361-R365 PolarHBondContact O-N 3.02Å
362T51.1Low52.2Low75 Ų75111.8 Ų111.846%0.4655%0.551SS.*Hα-helixtrans-59.8-42.4175.5-53.80000111.6K359 L360 R365 Y366K359-T362 PolarHBondContact O-N 3.19Å; L360-T362 VanDerWaalsContact C-N 3.35Å; L360-T362 PolarHBondContact O-N 2.7Å; T362-R365 PolarHBondContact O-N 3Å; T362-Y366 HydrophobicContact CG2-CD2 4.48Å; T362-Y366 HydrophobicContact CG2-CE2 4.08Å; T362-Y366 WeakPolarHBondContact O-CD2 3.25Å; T362-Y366 PolarHBondContact O-N 3.08Å
363V57.7Low51.7Low80 Ų80114.5 Ų114.549%0.48557%0.567SS.*Hα-helixtrans-66-44.9174.5175.20000111.3K359 L360 Y361 R365 Y366 L367K359-V363 PolarHBondContact O-N 3.12Å; L360-V363 PolarHBondContact O-N 3.29Å; Y361-V363 VanDerWaalsContact C-N 3.32Å; Y361-V363 PolarHBondContact O-N 2.67Å; V363-R365 VanDerWaalsContact C-N 3.27Å; V363-R365 PolarHBondContact O-N 3.29Å; V363-Y366 PolarHBondContact O-N 3.33Å; V363-Y366 VanDerWaalsContact O-N 3.1Å; V363-L367 HydrophobicContact CG1-CD1 4.01Å; V363-L367 HydrophobicContact CG1-CG 4.43Å; V363-L367 WeakPolarHBondContact O-CG 3.29Å; V363-L367 PolarHBondContact O-N 3.48Å
364M52.6Low52.1Low114 Ų114114.7 Ų114.756%0.56257%0.566SS**Hα-helixtrans-60.5-34.9177-69.7-72.5-73.700112.4L360 Y361 L367 S368L360-M364 HydrophobicContact CG-CG 4.4Å; L360-M364 WeakPolarHBondContact O-CB 3.43Å; L360-M364 VanDerWaalsContact O-CG 3.23Å; L360-M364 WeakPolarHBondContact O-CG 3.44Å; L360-M364 PolarHBondContact O-N 3.45Å; Y361-M364 PolarHBondContact O-N 3.16Å; M364-L367 CarbonylContact O-C 3.58Å; M364-L367 PolarHBondContact O-N 2.91Å; M364-L367 HydrophobicContact SD-CD1 4.47Å; M364-S368 PolarHBondContact O-N 3.32Å; M364-S368 PolarHBondContact O-OG 2.9Å
365R46.2Very low52.3Low162 Ų162114.7 Ų114.761%0.61157%0.566SS**Hα-helixtrans-65.3-35.2174.3174.2176156.5173.5-7.5112.7Y361 T362 V363 S368Y361-R365 HydrophobicContact CE1-CB 4.34Å; Y361-R365 WeakPolarHBondContact O-CB 3.32Å; Y361-R365 PolarHBondContact O-N 3.02Å; T362-R365 PolarHBondContact O-N 3Å; V363-R365 VanDerWaalsContact C-N 3.27Å; V363-R365 PolarHBondContact O-N 3.29Å; R365-S368 WeakPolarHBondContact CA-OG 3.33Å; R365-S368 PolarHBondContact O-OG 3.38Å
366Y56.1Low52.3Low167 Ų167115.5 Ų115.566%0.65558%0.575SS**Hα-helixtrans-72.3-36.2171-74.5-68.7000111.9T362 V363 S368 L369T362-Y366 HydrophobicContact CG2-CD2 4.48Å; T362-Y366 HydrophobicContact CG2-CE2 4.08Å; T362-Y366 WeakPolarHBondContact O-CD2 3.25Å; T362-Y366 PolarHBondContact O-N 3.08Å; V363-Y366 PolarHBondContact O-N 3.33Å; V363-Y366 VanDerWaalsContact O-N 3.1Å; Y366-S368 VanDerWaalsContact C-N 3.27Å; Y366-S368 PolarHBondContact O-N 3.27Å; Y366-L369 WeakPolarHBondContact O-CB 3.29Å; Y366-L369 WeakPolarHBondContact O-CG 3.23Å; Y366-L369 PolarHBondContact O-N 3.11Å
367L50.5Low52.5Low107 Ų107112.5 Ų112.556%0.5656%0.564SS**Hα-helixtrans-71.6-18.1175.2-65.2172.7000113.6V363 M364 L369V363-L367 HydrophobicContact CG1-CD1 4.01Å; V363-L367 HydrophobicContact CG1-CG 4.43Å; V363-L367 WeakPolarHBondContact O-CG 3.29Å; V363-L367 PolarHBondContact O-N 3.48Å; M364-L367 CarbonylContact O-C 3.58Å; M364-L367 PolarHBondContact O-N 2.91Å; M364-L367 HydrophobicContact SD-CD1 4.47Å; L367-L369 VanDerWaalsContact C-N 3.28Å; L367-L369 PolarHBondContact O-N 2.04Å
368S50.6Low52.6Low79 Ų79110.9 Ų110.955%0.55255%0.55SS**THydrogen-bonded Turntrans-84.59.1172.160.40000114.6M364 R365 Y366M364-S368 PolarHBondContact O-N 3.32Å; M364-S368 PolarHBondContact O-OG 2.9Å; R365-S368 WeakPolarHBondContact CA-OG 3.33Å; R365-S368 PolarHBondContact O-OG 3.38Å; Y366-S368 VanDerWaalsContact C-N 3.27Å; Y366-S368 PolarHBondContact O-N 3.27Å
369L47.9Very low52.6Low88 Ų88111.6 Ų111.646%0.46155%0.553SS.*SBendtrans-62.7151.1161.9-74.7167.8000109.9Y366 L367 W371Y366-L369 WeakPolarHBondContact O-CB 3.29Å; Y366-L369 WeakPolarHBondContact O-CG 3.23Å; Y366-L369 PolarHBondContact O-N 3.11Å; L367-L369 VanDerWaalsContact C-N 3.28Å; L367-L369 PolarHBondContact O-N 2.04Å; L369-W371 VanDerWaalsContact C-N 3.26Å; L369-W371 PolarHBondContact O-N 2.8Å
370P43.9Very low52.8Low100 Ų100105.1 Ų105.165%0.64953%0.534SS*.THydrogen-bonded Turntrans-76.521.2-136.5-23.336.4000119.1L504P370-L504 HydrophobicContact CG-CD2 4.48Å
371W49.2Very low52.6Low241 Ų241100.9 Ų100.991%0.91351%0.514SS*.THydrogen-bonded Turntrans-123.71.1-163.2-9757.8000117.2L369L369-W371 VanDerWaalsContact C-N 3.26Å; L369-W371 PolarHBondContact O-N 2.8Å
372I48.6Very low52.8Low135 Ų135103 Ų10369%0.69253%0.525SS*.  trans-135.697.5171.7-50.9178.9000110.6
373L51.1Low53.1Low80 Ų80103.2 Ų103.242%0.41952%0.523SS..  trans-66.8136153.4-99.382.4000108F375 L377 T378L373-F375 PolarHBondContact O-N 2.76Å; L373-L377 HydrophobicContact CD2-CB 4.48Å; L373-L377 HydrophobicContact CD2-CD2 4.06Å; L373-L377 HydrophobicContact CD2-CG 4.11Å; L373-L377 HydrophobicContact CG-CD2 4.21Å; L373-T378 HydrophobicContact CB-CG2 3.91Å; L373-T378 HydrophobicContact CD2-CG2 4.06Å
374P61.4Low52.9Low75 Ų75104.7 Ų104.749%0.48752%0.523SS..  trans-55.2140.5169.3-24.634.2000110.7D376 L377 T378P374-D376 PolarHBondContact O-N 3.5Å; P374-L377 HydrophobicContact CB-CB 4.27Å; P374-L377 WeakPolarHBondContact O-CA 3.32Å; P374-L377 WeakPolarHBondContact O-CB 3.37Å; P374-L377 PolarHBondContact O-N 3.3Å; P374-T378 PolarHBondContact O-N 2.87Å; P374-T378 PolarHBondContact O-OG1 2.85Å
375F52.7Low53.2Low159 Ų159102.3 Ų102.370%0.69751%0.512SS*.Hα-helixtrans-53.5-43.1-175.3-176.2-102.3000112.1L373 L377 T378 V379L373-F375 PolarHBondContact O-N 2.76Å; F375-L377 VanDerWaalsContact C-N 3.27Å; F375-L377 PolarHBondContact O-N 3.09Å; F375-T378 WeakPolarHBondContact CA-OG1 3.41Å; F375-T378 PolarHBondContact O-N 3.32Å; F375-T378 PolarHBondContact O-OG1 2.9Å; F375-V379 HydrophobicContact CD1-CG2 4.01Å; F375-V379 HydrophobicContact CE1-CG2 3.64Å; F375-V379 HydrophobicContact CE2-CG2 4.34Å; F375-V379 HydrophobicContact CZ-CG2 3.83Å; F375-V379 WeakPolarHBondContact O-CG2 3.39Å; F375-V379 PolarHBondContact O-N 2.98Å
376D53Low53.5Low127 Ų12797 Ų9768%0.67950%0.499SS*.Hα-helixtrans-62.2-31.4176.8-50.2-49.6000113P374 A380P374-D376 PolarHBondContact O-N 3.5Å; D376-A380 WeakPolarHBondContact O-CB 3.44Å; D376-A380 PolarHBondContact O-N 3.22Å
377L55Low53.5Low43 Ų4396.7 Ų96.723%0.22550%0.504CS..Hα-helixtrans-77.2-38177.2-167.665.7000111.2L373 P374 F375 T381L373-L377 HydrophobicContact CD2-CB 4.48Å; L373-L377 HydrophobicContact CD2-CD2 4.06Å; L373-L377 HydrophobicContact CD2-CG 4.11Å; L373-L377 HydrophobicContact CG-CD2 4.21Å; P374-L377 HydrophobicContact CB-CB 4.27Å; P374-L377 WeakPolarHBondContact O-CA 3.32Å; P374-L377 WeakPolarHBondContact O-CB 3.37Å; P374-L377 PolarHBondContact O-N 3.3Å; F375-L377 VanDerWaalsContact C-N 3.27Å; F375-L377 PolarHBondContact O-N 3.09Å; L377-T381 VanDerWaalsContact O-CB 3.26Å; L377-T381 WeakPolarHBondContact O-CB 3.49Å; L377-T381 PolarHBondContact O-N 3.42Å; L377-T381 PolarHBondContact O-OG1 3.35Å
378T54.6Low53.5Low63 Ų6398.6 Ų98.639%0.38750%0.503SS..Hα-helixtrans-62.9-43.1167.925.80000111.8L373 P374 F375 T381 F382L373-T378 HydrophobicContact CB-CG2 3.91Å; L373-T378 HydrophobicContact CD2-CG2 4.06Å; P374-T378 PolarHBondContact O-N 2.87Å; P374-T378 PolarHBondContact O-OG1 2.85Å; F375-T378 WeakPolarHBondContact CA-OG1 3.41Å; F375-T378 PolarHBondContact O-N 3.32Å; F375-T378 PolarHBondContact O-OG1 2.9Å; T378-T381 PolarHBondContact O-N 2.95Å; T378-F382 WeakPolarHBondContact O-CB 3.33Å; T378-F382 PolarHBondContact O-N 2.86Å
379V55.4Low53.3Low54 Ų5499.1 Ų99.133%0.32750%0.498SS..Hα-helixtrans-66.3-44.3177.6171.30000111.4F375 T381 F382 N383F375-V379 HydrophobicContact CD1-CG2 4.01Å; F375-V379 HydrophobicContact CE1-CG2 3.64Å; F375-V379 HydrophobicContact CE2-CG2 4.34Å; F375-V379 HydrophobicContact CZ-CG2 3.83Å; F375-V379 WeakPolarHBondContact O-CG2 3.39Å; F375-V379 PolarHBondContact O-N 2.98Å; V379-T381 VanDerWaalsContact C-N 3.29Å; V379-T381 PolarHBondContact O-N 3.1Å; V379-F382 PolarHBondContact O-N 2.88Å; V379-N383 WeakPolarHBondContact O-CB 3.42Å; V379-N383 VanDerWaalsContact O-CG 3.28Å; V379-N383 PolarHBondContact O-N 3.33Å
380A56.1Low53.6Low51 Ų51100.2 Ų100.242%0.42151%0.51SS..Hα-helixtrans-64.5-33.4175.900000112.8D376 K384D376-A380 WeakPolarHBondContact O-CB 3.44Å; D376-A380 PolarHBondContact O-N 3.22Å; A380-K384 WeakPolarHBondContact O-CB 3.47Å; A380-K384 PolarHBondContact O-N 2.89Å
381T55.8Low54.2Low35 Ų3599.1 Ų99.122%0.21551%0.505CS..Hα-helixtrans-72.7-44.4174.1-55.70000111P77 L377 T378 V379 K384 I385P77-T381 HydrophobicContact CG-CG2 4.09Å; L377-T381 VanDerWaalsContact O-CB 3.26Å; L377-T381 WeakPolarHBondContact O-CB 3.49Å; L377-T381 PolarHBondContact O-N 3.42Å; L377-T381 PolarHBondContact O-OG1 3.35Å; T378-T381 PolarHBondContact O-N 2.95Å; V379-T381 VanDerWaalsContact C-N 3.29Å; V379-T381 PolarHBondContact O-N 3.1Å; T381-K384 PolarHBondContact O-N 3.33Å; T381-I385 HydrophobicContact CG2-CD1 4.05Å; T381-I385 VanDerWaalsContact O-CG1 3.3Å; T381-I385 WeakPolarHBondContact O-CG1 3.27Å; T381-I385 PolarHBondContact O-N 2.91Å
382F58.5Low54.3Low128 Ų12890.1 Ų90.156%0.56147%0.472SS*.Hα-helixtrans-63.7-46178.6-173.4-99.1000111.8T378 V379 K384 I385 C386T378-F382 WeakPolarHBondContact O-CB 3.33Å; T378-F382 PolarHBondContact O-N 2.86Å; V379-F382 PolarHBondContact O-N 2.88Å; F382-K384 PolarHBondContact O-N 3.08Å; F382-I385 WeakPolarHBondContact O-CA 3.48Å; F382-I385 WeakPolarHBondContact O-CB 3.41Å; F382-I385 PolarHBondContact O-N 2.81Å; F382-C386 VanDerWaalsContact CE1-SG 3.54Å; F382-C386 PolarHBondContact O-N 2.84Å; F382-C386 PolarHBondContact O-SG 3.23Å; F382-C386 VanDerWaalsContact O-SG 3.35Å
383N58.2Low54.7Low80 Ų8086.1 Ų86.143%0.42846%0.456SS..Hα-helixtrans-61.3-43.2176.1-70.5-2.8000111.3V379 I385 C386 E387V379-N383 WeakPolarHBondContact O-CB 3.42Å; V379-N383 VanDerWaalsContact O-CG 3.28Å; V379-N383 PolarHBondContact O-N 3.33Å; N383-I385 VanDerWaalsContact C-N 3.26Å; N383-I385 PolarHBondContact O-N 3.33Å; N383-C386 PolarHBondContact O-N 3.41Å; N383-E387 WeakPolarHBondContact O-CB 3.48Å; N383-E387 WeakPolarHBondContact O-CG 3.23Å; N383-E387 PolarHBondContact O-N 3.26Å
384K54.2Low55.4Low111 Ų11186.6 Ų86.648%0.48346%0.459SS..Hα-helixtrans-63.8-26.3173.2-88-177.8164.71800114.4P77 A380 T381 F382 R388P77-K384 PolarHBondContact O-NZ 2.7Å; A380-K384 WeakPolarHBondContact O-CB 3.47Å; A380-K384 PolarHBondContact O-N 2.89Å; T381-K384 PolarHBondContact O-N 3.33Å; F382-K384 PolarHBondContact O-N 3.08Å; K384-R388 VanDerWaalsContact O-CB 3.3Å; K384-R388 WeakPolarHBondContact O-CB 3.43Å
385I58.4Low55.4Low64 Ų6483.6 Ų83.633%0.32844%0.441SS..Hα-helixtrans-74.9-50171.8-70.8163.7000109.1T381 F382 N383 R388 M389T381-I385 HydrophobicContact CG2-CD1 4.05Å; T381-I385 VanDerWaalsContact O-CG1 3.3Å; T381-I385 WeakPolarHBondContact O-CG1 3.27Å; T381-I385 PolarHBondContact O-N 2.91Å; F382-I385 WeakPolarHBondContact O-CA 3.48Å; F382-I385 WeakPolarHBondContact O-CB 3.41Å; F382-I385 PolarHBondContact O-N 2.81Å; N383-I385 VanDerWaalsContact C-N 3.26Å; N383-I385 PolarHBondContact O-N 3.33Å; I385-R388 CarbonylContact O-C 3.5Å; I385-R388 PolarHBondContact O-N 3.44Å; I385-R388 VanDerWaalsContact O-N 3.16Å; I385-M389 HydrophobicContact CG2-CE 4.08Å; I385-M389 HydrophobicContact CG2-CG 4.43Å; I385-M389 WeakPolarHBondContact O-CG 3.49Å; I385-M389 PolarHBondContact O-N 3.45Å
386C52.3Low55.9Low49 Ų4977 Ų7733%0.33141%0.414SS..Hα-helixtrans-62.2-47-178.8-690000113.4F382 N383 R388 M389F382-C386 VanDerWaalsContact CE1-SG 3.54Å; F382-C386 PolarHBondContact O-N 2.84Å; F382-C386 PolarHBondContact O-SG 3.23Å; F382-C386 VanDerWaalsContact O-SG 3.35Å; N383-C386 PolarHBondContact O-N 3.41Å; C386-R388 PolarHBondContact O-N 3.23Å; C386-R388 VanDerWaalsContact O-N 3.15Å; C386-M389 PolarHBondContact O-N 3.41Å
387E56Low56.7Low162 Ų16276 Ų7676%0.75740%0.403SS*.THydrogen-bonded Turntrans-60.8-23175.9-72.8175.3172.500112.9N383N383-E387 WeakPolarHBondContact O-CB 3.48Å; N383-E387 WeakPolarHBondContact O-CG 3.23Å; N383-E387 PolarHBondContact O-N 3.26Å
388R50.6Low57.5Low146 Ų14678.4 Ų78.455%0.55141%0.413SS*.THydrogen-bonded Turntrans-107.3-7-176.2-146.1173.1-167.2118.4-0.3113.6K384 I385 C386 P390 S391 F392K384-R388 VanDerWaalsContact O-CB 3.3Å; K384-R388 WeakPolarHBondContact O-CB 3.43Å; I385-R388 CarbonylContact O-C 3.5Å; I385-R388 PolarHBondContact O-N 3.44Å; I385-R388 VanDerWaalsContact O-N 3.16Å; C386-R388 PolarHBondContact O-N 3.23Å; C386-R388 VanDerWaalsContact O-N 3.15Å; R388-P390 VanDerWaalsContact C-N 3.35Å; R388-P390 VanDerWaalsContact O-N 3.16Å; R388-S391 PolarHBondContact O-N 3.49Å; R388-S391 PolarHBondContact O-OG 3Å; R388-F392 WeakPolarHBondContact O-CB 3.49Å; R388-F392 PolarHBondContact O-N 2.97Å
389M47.3Very low58.2Low91 Ų9175.6 Ų75.645%0.44840%0.396SS..Hα-helixtrans-47.3-43.8-174.6-93.8-166.3178.400115I385 C386 S391 F392 C393I385-M389 HydrophobicContact CG2-CE 4.08Å; I385-M389 HydrophobicContact CG2-CG 4.43Å; I385-M389 WeakPolarHBondContact O-CG 3.49Å; I385-M389 PolarHBondContact O-N 3.45Å; C386-M389 PolarHBondContact O-N 3.41Å; M389-S391 VanDerWaalsContact C-N 3.35Å; M389-S391 PolarHBondContact O-N 3.22Å; M389-F392 PolarHBondContact O-N 2.88Å; M389-C393 PolarHBondContact O-N 3.47Å; M389-C393 VanDerWaalsContact O-N 3.1Å; M389-C393 PolarHBondContact O-SG 3.05Å; M389-C393 VanDerWaalsContact O-SG 3.39Å
390P53.2Low59.1Low110 Ų11077.2 Ų77.271%0.71440%0.403SS*.Hα-helixtrans-58.8-39.4-175.7-27.336.2000114.5R388R388-P390 VanDerWaalsContact C-N 3.35Å; R388-P390 VanDerWaalsContact O-N 3.16Å
391S56.7Low60Low77 Ų7778.5 Ų78.554%0.53840%0.403SS..Hα-helixtrans-97-23177.156.50000113.2R388 M389R388-S391 PolarHBondContact O-N 3.49Å; R388-S391 PolarHBondContact O-OG 3Å; M389-S391 VanDerWaalsContact C-N 3.35Å; M389-S391 PolarHBondContact O-N 3.22Å
392F52Low60.9Low53 Ų5377.1 Ų77.123%0.23239%0.394CS..Hα-helixtrans-61.9-42174.8178.5-95.2000112T145 R388 M389 D394 S396T145-F392 HydrophobicContact CG2-CE2 4.08Å; R388-F392 WeakPolarHBondContact O-CB 3.49Å; R388-F392 PolarHBondContact O-N 2.97Å; M389-F392 PolarHBondContact O-N 2.88Å; F392-D394 PolarHBondContact O-N 3.11Å; F392-S396 WeakPolarHBondContact O-CB 3.41Å; F392-S396 PolarHBondContact O-N 3.39Å; F392-S396 PolarHBondContact O-OG 3.13Å
393C56.1Low61.5Low51 Ų5172.6 Ų72.635%0.34538%0.375SS..Hα-helixtrans-54.2-50.8-175.1-82.30000113.7M389 S396 K397M389-C393 PolarHBondContact O-N 3.47Å; M389-C393 VanDerWaalsContact O-N 3.1Å; M389-C393 PolarHBondContact O-SG 3.05Å; M389-C393 VanDerWaalsContact O-SG 3.39Å; C393-S396 PolarHBondContact O-OG 3.43Å; C393-K397 WeakPolarHBondContact O-CB 3.48Å; C393-K397 WeakPolarHBondContact O-CD 3.36Å; C393-K397 WeakPolarHBondContact O-CE 3.46Å; C393-K397 WeakPolarHBondContact O-CG 3.49Å; C393-K397 PolarHBondContact O-N 3.32Å
394D64.9Low62.1Low89 Ų8972.5 Ų72.548%0.47637%0.374SS..Hα-helixtrans-86.8-27-169.2-61-27.4000113.5F392 K397 Q398F392-D394 PolarHBondContact O-N 3.11Å; D394-K397 IonicContact OD1-NZ 3.15Å; D394-K397 PolarHBondContact OD1-NZ 2.82Å; D394-Q398 WeakPolarHBondContact O-CG 3.3Å; D394-Q398 PolarHBondContact O-N 2.74Å; D394-Q398 PolarHBondContact O-NE2 3.45Å
395A61.7Low62.8Low13 Ų1372.8 Ų72.811%0.10738%0.375CS..Hα-helixtrans-72-43.7169.400000111.8Q398 V399A395-Q398 PolarHBondContact O-N 2.69Å; A395-V399 WeakPolarHBondContact O-CG2 3.28Å; A395-V399 PolarHBondContact O-N 2.95Å; A395-V399 VanDerWaalsContact O-N 3.08Å
396S62.7Low63.1Low19 Ų1971.3 Ų71.313%0.13337%0.367CS..Hα-helixtrans-70.2-34.1178.964.70000112.8F392 C393 V399 L400F392-S396 WeakPolarHBondContact O-CB 3.41Å; F392-S396 PolarHBondContact O-N 3.39Å; F392-S396 PolarHBondContact O-OG 3.13Å; C393-S396 PolarHBondContact O-OG 3.43Å; S396-V399 PolarHBondContact O-N 3.44Å; S396-L400 VanDerWaalsContact O-CB 3.22Å; S396-L400 WeakPolarHBondContact O-CB 3.28Å; S396-L400 PolarHBondContact O-N 3Å
397K71.3Confident63.2Low106 Ų10674.6 Ų74.646%0.46138%0.381SS..Hα-helixtrans-57.7-51.7167.8-76.1166.1-154.81650111.4C393 D394 V399 L400 D401C393-K397 WeakPolarHBondContact O-CB 3.48Å; C393-K397 WeakPolarHBondContact O-CD 3.36Å; C393-K397 WeakPolarHBondContact O-CE 3.46Å; C393-K397 WeakPolarHBondContact O-CG 3.49Å; C393-K397 PolarHBondContact O-N 3.32Å; D394-K397 IonicContact OD1-NZ 3.15Å; D394-K397 PolarHBondContact OD1-NZ 2.82Å; K397-V399 VanDerWaalsContact C-N 3.3Å; K397-V399 PolarHBondContact O-N 3.29Å; K397-L400 PolarHBondContact O-N 3.19Å; K397-L400 VanDerWaalsContact O-N 3.13Å; K397-D401 VanDerWaalsContact O-CB 3.28Å; K397-D401 WeakPolarHBondContact O-CB 3.4Å; K397-D401 VanDerWaalsContact O-CG 3.25Å; K397-D401 PolarHBondContact O-N 3.36Å
398Q72.3Confident62.9Low94 Ų9473 Ų7344%0.43938%0.377SS..Hα-helixtrans-59.2-40.6-180-75.8170.581.500112.6L112 D394 A395 F402L112-Q398 HydrophobicContact CD2-CB 4.14Å; D394-Q398 WeakPolarHBondContact O-CG 3.3Å; D394-Q398 PolarHBondContact O-N 2.74Å; D394-Q398 PolarHBondContact O-NE2 3.45Å; A395-Q398 PolarHBondContact O-N 2.69Å; Q398-F402 VanDerWaalsContact O-CB 3.23Å; Q398-F402 WeakPolarHBondContact O-CB 3.01Å; Q398-F402 PolarHBondContact O-N 2.69Å
399V69.1Low62.5Low4 Ų471.5 Ų71.52%0.02438%0.38CS..Hα-helixtrans-66.3-43.5174.1168.50000112.1L112 P140 F141 P147 A395 S396 K397 F402 L403L112-V399 HydrophobicContact CD1-CG2 4.2Å; L112-V399 HydrophobicContact CD2-CG2 4.17Å; P140-V399 HydrophobicContact CB-CG1 3.58Å; P140-V399 HydrophobicContact CG-CG1 4.26Å; F141-V399 HydrophobicContact CD2-CG1 4.4Å; F141-V399 HydrophobicContact CE2-CG1 3.66Å; F141-V399 HydrophobicContact CZ-CG1 4.08Å; P147-V399 HydrophobicContact CG-CG2 4.16Å; A395-V399 WeakPolarHBondContact O-CG2 3.28Å; A395-V399 PolarHBondContact O-N 2.95Å; A395-V399 VanDerWaalsContact O-N 3.08Å; S396-V399 PolarHBondContact O-N 3.44Å; K397-V399 VanDerWaalsContact C-N 3.3Å; K397-V399 PolarHBondContact O-N 3.29Å; V399-F402 PolarHBondContact O-N 2.79Å; V399-L403 HydrophobicContact CG1-CD1 4.06Å; V399-L403 VanDerWaalsContact O-CG 3.29Å; V399-L403 WeakPolarHBondContact O-CG 3.35Å; V399-L403 PolarHBondContact O-N 3.29Å
400L73.2Confident62.4Low88 Ų8872.4 Ų72.446%0.46138%0.383SS..Hα-helixtrans-69.1-45.6179.8-176.761.9000111.3S396 K397 F402 L403 L404S396-L400 VanDerWaalsContact O-CB 3.22Å; S396-L400 WeakPolarHBondContact O-CB 3.28Å; S396-L400 PolarHBondContact O-N 3Å; K397-L400 PolarHBondContact O-N 3.19Å; K397-L400 VanDerWaalsContact O-N 3.13Å; L400-F402 VanDerWaalsContact C-N 3.28Å; L400-F402 PolarHBondContact O-N 3.5Å; L400-L403 PolarHBondContact O-N 2.75Å; L400-L404 HydrophobicContact CD1-CD1 4.29Å; L400-L404 HydrophobicContact CD1-CG 4.24Å; L400-L404 HydrophobicContact CG-CD1 3.93Å; L400-L404 HydrophobicContact CG-CG 4.32Å; L400-L404 WeakPolarHBondContact O-CB 3.34Å; L400-L404 VanDerWaalsContact O-CG 3.25Å; L400-L404 WeakPolarHBondContact O-CG 3.47Å; L400-L404 PolarHBondContact O-N 3.48Å
401D76.4Confident61.4Low79 Ų7971.8 Ų71.842%0.42238%0.381SS..Hα-helixtrans-58.9-39.3173.3-72.6-6.1000111.3K397 K405K397-D401 VanDerWaalsContact O-CB 3.28Å; K397-D401 WeakPolarHBondContact O-CB 3.4Å; K397-D401 VanDerWaalsContact O-CG 3.25Å; K397-D401 PolarHBondContact O-N 3.36Å; D401-K405 VanDerWaalsContact O-CB 3.29Å; D401-K405 WeakPolarHBondContact O-CB 3.29Å; D401-K405 VanDerWaalsContact O-CD 3.3Å; D401-K405 WeakPolarHBondContact O-CD 3.39Å; D401-K405 WeakPolarHBondContact O-CG 3.23Å; D401-K405 PolarHBondContact O-N 3.43Å
402F74.7Confident60.2Low6 Ų674.3 Ų74.33%0.02640%0.396CS..Hα-helixtrans-61.8-51.7173.6172.7-97.2000111.3T110 L112 G115 I156 W160 Q398 V399 L400 L404 K405 Q406T110-F402 HydrophobicContact CG2-CZ 4.14Å; L112-F402 HydrophobicContact CD1-CB 3.73Å; L112-F402 HydrophobicContact CD1-CD1 4.29Å; L112-F402 HydrophobicContact CD1-CD2 4.46Å; L112-F402 HydrophobicContact CD1-CG 3.88Å; L112-F402 WeakPolarHBondContact O-CD2 3.06Å; G115-F402 VanDerWaalsContact CA-CE2 3.5Å; I156-F402 HydrophobicContact CD1-CD1 3.86Å; I156-F402 HydrophobicContact CD1-CE1 3.36Å; I156-F402 HydrophobicContact CD1-CZ 3.95Å; W160-F402 HydrophobicContact CE3-CE1 4.27Å; Q398-F402 VanDerWaalsContact O-CB 3.23Å; Q398-F402 WeakPolarHBondContact O-CB 3.01Å; Q398-F402 PolarHBondContact O-N 2.69Å; V399-F402 PolarHBondContact O-N 2.79Å; L400-F402 VanDerWaalsContact C-N 3.28Å; L400-F402 PolarHBondContact O-N 3.5Å; F402-L404 PolarHBondContact O-N 2.89Å; F402-K405 PolarHBondContact O-N 2.96Å; F402-Q406 HydrophobicContact CD1-CG 4.43Å; F402-Q406 HydrophobicContact CE1-CG 3.84Å; F402-Q406 HydrophobicContact CE2-CG 3.96Å; F402-Q406 HydrophobicContact CZ-CG 3.59Å; F402-Q406 WeakPolarHBondContact O-CG 3.37Å; F402-Q406 PolarHBondContact O-N 3.4Å
403L70.4Confident59.2Low32 Ų3277.1 Ų77.117%0.16842%0.422CS..Hα-helixtrans-64-40.5-179.9-68.7169.8000111.8F141 W160 V399 L400 Q406 L407F141-L403 HydrophobicContact CD2-CD1 4.31Å; F141-L403 HydrophobicContact CE2-CD1 3.77Å; W160-L403 HydrophobicContact CE3-CD2 4.38Å; W160-L403 HydrophobicContact CH2-CD2 3.36Å; W160-L403 HydrophobicContact CZ2-CD2 4.07Å; W160-L403 HydrophobicContact CZ3-CD2 3.55Å; V399-L403 HydrophobicContact CG1-CD1 4.06Å; V399-L403 VanDerWaalsContact O-CG 3.29Å; V399-L403 WeakPolarHBondContact O-CG 3.35Å; V399-L403 PolarHBondContact O-N 3.29Å; L400-L403 PolarHBondContact O-N 2.75Å; L403-Q406 PolarHBondContact O-N 2.85Å; L403-L407 VanDerWaalsContact O-CG 3.28Å; L403-L407 WeakPolarHBondContact O-CG 3.23Å; L403-L407 PolarHBondContact O-N 3.36Å
404L71.4Confident58Low79 Ų7980.9 Ų80.941%0.41443%0.429SS..Hα-helixtrans-63.2-44.8174.2-71.8174000111.4L400 F402 Q406 L407 D408L400-L404 HydrophobicContact CD1-CD1 4.29Å; L400-L404 HydrophobicContact CD1-CG 4.24Å; L400-L404 HydrophobicContact CG-CD1 3.93Å; L400-L404 HydrophobicContact CG-CG 4.32Å; L400-L404 WeakPolarHBondContact O-CB 3.34Å; L400-L404 VanDerWaalsContact O-CG 3.25Å; L400-L404 WeakPolarHBondContact O-CG 3.47Å; L400-L404 PolarHBondContact O-N 3.48Å; F402-L404 PolarHBondContact O-N 2.89Å; L404-Q406 VanDerWaalsContact C-N 3.32Å; L404-Q406 PolarHBondContact O-N 3.42Å; L404-L407 CarbonylContact O-C 3.51Å; L404-L407 PolarHBondContact O-N 3.01Å; L404-D408 PolarHBondContact O-N 2.81Å
405K67.8Low56.2Low116 Ų11680.3 Ų80.350%0.50443%0.428SS..Hα-helixtrans-59.7-39.9173.5-74.2162.9-171.11670112.3D401 F402 L407 L409D401-K405 VanDerWaalsContact O-CB 3.29Å; D401-K405 WeakPolarHBondContact O-CB 3.29Å; D401-K405 VanDerWaalsContact O-CD 3.3Å; D401-K405 WeakPolarHBondContact O-CD 3.39Å; D401-K405 WeakPolarHBondContact O-CG 3.23Å; D401-K405 PolarHBondContact O-N 3.43Å; F402-K405 PolarHBondContact O-N 2.96Å; K405-L407 VanDerWaalsContact C-N 3.33Å; K405-L409 VanDerWaalsContact O-CB 3.28Å; K405-L409 WeakPolarHBondContact O-CB 3.47Å; K405-L409 WeakPolarHBondContact O-CD1 3.19Å; K405-L409 VanDerWaalsContact O-CG 3.26Å; K405-L409 WeakPolarHBondContact O-CG 3.46Å; K405-L409 PolarHBondContact O-N 3.04Å
406Q64Low54.6Low34 Ų3483.7 Ų83.716%0.15945%0.447CS..Hα-helixtrans-65.5-35.8174.3-66.3-59.6-47.200112F402 L403 L404 H410F402-Q406 HydrophobicContact CD1-CG 4.43Å; F402-Q406 HydrophobicContact CE1-CG 3.84Å; F402-Q406 HydrophobicContact CE2-CG 3.96Å; F402-Q406 HydrophobicContact CZ-CG 3.59Å; F402-Q406 WeakPolarHBondContact O-CG 3.37Å; F402-Q406 PolarHBondContact O-N 3.4Å; L403-Q406 PolarHBondContact O-N 2.85Å; L404-Q406 VanDerWaalsContact C-N 3.32Å; L404-Q406 PolarHBondContact O-N 3.42Å; Q406-H410 PolarHBondContact O-CD2 3.21Å
407L54.8Low53Low118 Ų11889 Ų8962%0.61847%0.468SS*.Hα-helixtrans-73.3-40.8177-71166.7000113L403 L404 K405 H410L403-L407 VanDerWaalsContact O-CG 3.28Å; L403-L407 WeakPolarHBondContact O-CG 3.23Å; L403-L407 PolarHBondContact O-N 3.36Å; L404-L407 CarbonylContact O-C 3.51Å; L404-L407 PolarHBondContact O-N 3.01Å; K405-L407 VanDerWaalsContact C-N 3.33Å; L407-H410 VanDerWaalsContact O-CB 3.25Å; L407-H410 WeakPolarHBondContact O-CB 3.43Å; L407-H410 PolarHBondContact O-N 2.88Å; L407-H410 VanDerWaalsContact O-N 3.08Å
408D49.8Very low50.9Low128 Ų12885.8 Ų85.868%0.68446%0.456SS*.Hα-helixtrans-68.7-34.2176.2-77.9-28.9000111.7L404 H410L404-D408 PolarHBondContact O-N 2.81Å; D408-H410 PolarHBondContact O-N 2.78Å
409L43.4Very low48.9Very low114 Ų11483.3 Ų83.360%0.59745%0.445SS*.THydrogen-bonded Turntrans-67.37.2169.1-76168.3000114.1K405 R414K405-L409 VanDerWaalsContact O-CB 3.28Å; K405-L409 WeakPolarHBondContact O-CB 3.47Å; K405-L409 WeakPolarHBondContact O-CD1 3.19Å; K405-L409 VanDerWaalsContact O-CG 3.26Å; K405-L409 WeakPolarHBondContact O-CG 3.46Å; K405-L409 PolarHBondContact O-N 3.04Å; L409-R414 PolarHBondContact O-NE 3.4Å; L409-R414 PolarHBondContact O-NH2 2.89Å
410H43.6Very low46.9Very low110 Ų11084.4 Ų84.451%0.50945%0.452SS..THydrogen-bonded Turntrans-114.78-177.7-106.7-86.5000115Q406 L407 D408 R414Q406-H410 PolarHBondContact O-CD2 3.21Å; L407-H410 VanDerWaalsContact O-CB 3.25Å; L407-H410 WeakPolarHBondContact O-CB 3.43Å; L407-H410 PolarHBondContact O-N 2.88Å; L407-H410 VanDerWaalsContact O-N 3.08Å; D408-H410 PolarHBondContact O-N 2.78Å; H410-R414 VanDerWaalsContact CD2-CZ 3.48Å; H410-R414 PolarHBondContact CD2-NH2 2.99Å; H410-R414 VanDerWaalsContact CD2-NH2 3.25Å; H410-R414 PolarHBondContact CE1-NH1 3.43Å; H410-R414 VanDerWaalsContact NE2-CZ 3.27Å; H410-R414 PolarHBondContact NE2-NH1 2.89Å; H410-R414 PolarHBondContact NE2-NH2 2.94Å
411S33.2Very low45Very low98 Ų9883.7 Ų83.769%0.68545%0.446SS*.SBendtrans-135133.7172.4-770000113.6
412P31.6Very low42.8Very low130 Ų13083.3 Ų83.384%0.84444%0.444SS*.SBendcis-13478.5-14.437.3-16.9000112.1
413S30.4Very low40.7Very low111 Ų11186.4 Ų86.478%0.77647%0.471SS*.  trans-142.80.3-178.159.10000116.2T415S413-T415 PolarHBondContact O-N 2.72Å
414R31.4Very low38.6Very low131 Ų13187.7 Ų87.749%0.49448%0.477SS..  trans-75.9112.9-177.5-64.2-163.6-169.4-176.411.9111.9L409 H410 V416L409-R414 PolarHBondContact O-NE 3.4Å; L409-R414 PolarHBondContact O-NH2 2.89Å; H410-R414 VanDerWaalsContact CD2-CZ 3.48Å; H410-R414 PolarHBondContact CD2-NH2 2.99Å; H410-R414 VanDerWaalsContact CD2-NH2 3.25Å; H410-R414 PolarHBondContact CE1-NH1 3.43Å; H410-R414 VanDerWaalsContact NE2-CZ 3.27Å; H410-R414 PolarHBondContact NE2-NH1 2.89Å; H410-R414 PolarHBondContact NE2-NH2 2.94Å; R414-V416 PolarHBondContact O-N 3.02Å
415T27Very low36.9Very low76 Ų7689.7 Ų89.747%0.46649%0.493SS..  trans-58.1116.7162.548.20000110S413 K417 N482S413-T415 PolarHBondContact O-N 2.72Å; T415-K417 PolarHBondContact O-N 2.94Å; T415-N482 HydrophobicContact CG2-CB 4.42Å
416V28.1Very low35.1Very low84 Ų8492.6 Ų92.651%0.50951%0.508SS..  trans-75.5109.7169.4-174.90000107.7R414 L418R414-V416 PolarHBondContact O-N 3.02Å; V416-L418 VanDerWaalsContact C-N 3.26Å; V416-L418 HydrophobicContact CG1-CD2 4.47Å; V416-L418 HydrophobicContact CG1-CG 4.12Å; V416-L418 PolarHBondContact O-N 2.88Å
417K28.6Very low33.5Very low131 Ų13195.1 Ų95.157%0.5752%0.521SS*.  trans-75.480179-163.8-164.1-178.2-165.50110.3T415 M419 T480T415-K417 PolarHBondContact O-N 2.94Å; K417-M419 VanDerWaalsContact C-N 3.3Å; K417-M419 HydrophobicContact CD-CG 4.05Å; K417-M419 HydrophobicContact CD-SD 3.84Å; K417-M419 WeakPolarHBondContact CE-SD 3.28Å; K417-M419 HydrophobicContact CG-CG 4.17Å; K417-M419 PolarHBondContact NZ-SD 2.9Å; K417-M419 PolarHBondContact O-N 3.46Å; K417-T480 HydrophobicContact CG-CG2 4.34Å
418L28.8Very low32.3Very low38 Ų3896 Ų9620%0.19953%0.527CS..  trans-70.182.7173.3-75.8166.8000110.6L194 V416 F479 V481L194-L418 HydrophobicContact CD2-CD2 3.71Å; V416-L418 VanDerWaalsContact C-N 3.26Å; V416-L418 HydrophobicContact CG1-CD2 4.47Å; V416-L418 HydrophobicContact CG1-CG 4.12Å; V416-L418 PolarHBondContact O-N 2.88Å; L418-F479 WeakPolarHBondContact O-CD2 3.27Å; L418-F479 WeakPolarHBondContact O-CE2 3.47Å; L418-V481 HydrophobicContact CB-CG2 4.35Å; L418-V481 HydrophobicContact CD1-CB 4.2Å; L418-V481 HydrophobicContact CD1-CG2 4.37Å
419M28.4Very low31.6Very low43 Ų4395.3 Ų95.321%0.21252%0.518CS..  trans-75.6143.4168.6-75.9174.951.400110.7L195 K417L195-M419 WeakPolarHBondContact CD1-O 3.41Å; K417-M419 VanDerWaalsContact C-N 3.3Å; K417-M419 HydrophobicContact CD-CG 4.05Å; K417-M419 HydrophobicContact CD-SD 3.84Å; K417-M419 WeakPolarHBondContact CE-SD 3.28Å; K417-M419 HydrophobicContact CG-CG 4.17Å; K417-M419 PolarHBondContact NZ-SD 2.9Å; K417-M419 PolarHBondContact O-N 3.46Å
420C28.9Very low31.3Very low27 Ų2793.9 Ų93.918%0.18252%0.517CS..  trans-138.972.3-175.5177.20000109.3L422 F479C420-L422 PolarHBondContact O-N 3.08Å; C420-F479 HydrophobicContact CB-CD1 4.37Å; C420-F479 HydrophobicContact CB-CE1 3.49Å; C420-F479 VanDerWaalsContact CB-CE1 3.49Å; C420-F479 HydrophobicContact CB-CE2 4.03Å; C420-F479 HydrophobicContact CB-CZ 3.29Å
421Q31.5Very low31.1Very low72 Ų7295.7 Ų95.734%0.33653%0.53SS..  trans-62.7132176.5-69.5179.1-41.200111E180 N476E180-Q421 PolarHBondContact OE1-OE1 3.33Å; Q421-N476 PolarHBondContact NE2-OD1 3.36Å
422L30.3Very low31.1Very low71 Ų7195 Ų9537%0.37252%0.519SS..  trans-112.596.6173.1-175.373.3000108.9C420 I424 M568C420-L422 PolarHBondContact O-N 3.08Å; L422-I424 HydrophobicContact CD2-CG1 4.33Å; L422-I424 HydrophobicContact CG-CG1 4.37Å; L422-I424 PolarHBondContact O-N 3.29Å; L422-I424 VanDerWaalsContact O-N 3.12Å; L422-M568 HydrophobicContact CD2-SD 4.11Å
423A30.8Very low31.4Very low71 Ų7191.7 Ų91.759%0.58750%0.499SS*.  trans-74.4100.7176.900000110.5T425A423-T425 PolarHBondContact O-N 3.15Å; A423-T425 VanDerWaalsContact O-N 3.1Å
424I28Very low31.9Very low60 Ų6090 Ų9031%0.30849%0.487SS..  trans-79.488.4176.6-55.9177.5000109.1L422 M427L422-I424 HydrophobicContact CD2-CG1 4.33Å; L422-I424 HydrophobicContact CG-CG1 4.37Å; L422-I424 PolarHBondContact O-N 3.29Å; L422-I424 VanDerWaalsContact O-N 3.12Å; I424-M427 HydrophobicContact CG2-CE 4Å; I424-M427 HydrophobicContact CG2-CG 4.16Å
425T33.9Very low32.2Very low120 Ų12088.9 Ų88.974%0.73649%0.491SS*.  trans-88.6117.7171.756.10000110.7A423A423-T425 PolarHBondContact O-N 3.15Å; A423-T425 VanDerWaalsContact O-N 3.1Å
426E30.9Very low32.7Very low178 Ų17888 Ų8883%0.83249%0.485SS*.  trans58.977.9169-60.3-175.9-167.100116.4
427M29.5Very low33.2Very low87 Ų8786.3 Ų86.343%0.42948%0.48SS..  trans-94.6127.3152.5-71.6-158.7-66.200110I424 F429I424-M427 HydrophobicContact CG2-CE 4Å; I424-M427 HydrophobicContact CG2-CG 4.16Å; M427-F429 HydrophobicContact CB-CD2 4.32Å; M427-F429 HydrophobicContact CB-CE2 3.88Å; M427-F429 HydrophobicContact CB-CZ 4.2Å; M427-F429 HydrophobicContact CE-CE1 4.29Å; M427-F429 HydrophobicContact CE-CZ 3.83Å; M427-F429 VanDerWaalsContact O-CD2 3.23Å; M427-F429 WeakPolarHBondContact O-CD2 3.15Å; M427-F429 PolarHBondContact O-N 3.3Å
428N30.8Very low33.7Very low137 Ų13785 Ų8573%0.73348%0.479SS*.  trans-89.997.8174.6-170.98000109.8S430N428-S430 PolarHBondContact O-N 3.4Å; N428-S430 VanDerWaalsContact O-N 3.08Å
429F34.3Very low34Very low113 Ų11388.8 Ų88.850%0.49650%0.497SS..G310 helixtrans-69.7-1.6-170.6-73.3-93.3000115.3M427 N431 L432M427-F429 HydrophobicContact CB-CD2 4.32Å; M427-F429 HydrophobicContact CB-CE2 3.88Å; M427-F429 HydrophobicContact CB-CZ 4.2Å; M427-F429 HydrophobicContact CE-CE1 4.29Å; M427-F429 HydrophobicContact CE-CZ 3.83Å; M427-F429 VanDerWaalsContact O-CD2 3.23Å; M427-F429 WeakPolarHBondContact O-CD2 3.15Å; M427-F429 PolarHBondContact O-N 3.3Å; F429-N431 PolarHBondContact O-N 2.92Å; F429-L432 HydrophobicContact CB-CD1 4.49Å; F429-L432 HydrophobicContact CD1-CD1 4.01Å; F429-L432 PolarHBondContact O-N 3.28Å
430S38.2Very low34.3Very low84 Ų8491.8 Ų91.859%0.58751%0.509SS*.G310 helixtrans-58.8-13-173.964.70000116.1N428N428-S430 PolarHBondContact O-N 3.4Å; N428-S430 VanDerWaalsContact O-N 3.08Å
431N38Very low34.7Very low147 Ų14795.4 Ų95.479%0.78653%0.527SS*.G310 helixtrans-114.46.1-172.6-64.79.8000114F429F429-N431 PolarHBondContact O-N 2.92Å
432L34Very low34.8Very low84 Ų8498.1 Ų98.144%0.4454%0.543SS..SBendtrans-88.9144.1176.1-75.8100.5000112.2F429 V436F429-L432 HydrophobicContact CB-CD1 4.49Å; F429-L432 HydrophobicContact CD1-CD1 4.01Å; F429-L432 PolarHBondContact O-N 3.28Å; L432-V436 HydrophobicContact CD2-CB 3.95Å; L432-V436 HydrophobicContact CD2-CG1 3.64Å
433S38.1Very low35Very low61 Ų61101.4 Ų101.443%0.42756%0.555SS.*  trans-62.4149.1169.5-171.80000110.8D435 V436 A437S433-D435 PolarHBondContact O-N 3.27Å; S433-D435 VanDerWaalsContact O-N 3.08Å; S433-D435 PolarHBondContact OG-OD2 2.98Å; S433-V436 PolarHBondContact O-N 2.82Å; S433-A437 PolarHBondContact O-N 3.34Å
434S40.5Very low35.2Very low75 Ų75103.8 Ų103.852%0.52455%0.554SS.*Hα-helixtrans-47.8-36.3172.544.70000112.9V436 A437 N438S434-V436 VanDerWaalsContact C-N 3.26Å; S434-V436 PolarHBondContact O-N 2.82Å; S434-A437 PolarHBondContact O-N 3.07Å; S434-N438 PolarHBondContact O-N 3.08Å; S434-N438 PolarHBondContact O-ND2 2.88Å
435D37.5Very low35.5Very low108 Ų108104.9 Ų104.958%0.57857%0.572SS**Hα-helixtrans-70.6-25.5-173.7-37-45.2000112S433 M439S433-D435 PolarHBondContact O-N 3.27Å; S433-D435 VanDerWaalsContact O-N 3.08Å; S433-D435 PolarHBondContact OG-OD2 2.98Å; D435-M439 PolarHBondContact O-N 3.18Å
436V37.5Very low35.6Very low58 Ų58104.1 Ų104.135%0.35257%0.567SS.*Hα-helixtrans-85.1-35.8176-165.70000110.8L432 S433 S434 M439 F440L432-V436 HydrophobicContact CD2-CB 3.95Å; L432-V436 HydrophobicContact CD2-CG1 3.64Å; S433-V436 PolarHBondContact O-N 2.82Å; S434-V436 VanDerWaalsContact C-N 3.26Å; S434-V436 PolarHBondContact O-N 2.82Å; V436-M439 WeakPolarHBondContact O-CB 3.44Å; V436-M439 PolarHBondContact O-N 3.24Å; V436-F440 HydrophobicContact CG1-CD2 4.28Å; V436-F440 HydrophobicContact CG1-CE2 4.04Å; V436-F440 WeakPolarHBondContact O-CD2 3.22Å; V436-F440 PolarHBondContact O-N 3.09Å
437A38.1Very low35.8Very low48 Ų48102.7 Ų102.740%0.39757%0.565SS.*Hα-helixtrans-59.9-51.117300000111.1S433 S434 M439 F440 D441S433-A437 PolarHBondContact O-N 3.34Å; S434-A437 PolarHBondContact O-N 3.07Å; A437-M439 PolarHBondContact O-N 3.2Å; A437-M439 VanDerWaalsContact O-N 3.1Å; A437-F440 PolarHBondContact O-N 3.33Å; A437-D441 PolarHBondContact O-N 3.21Å; A437-D441 VanDerWaalsContact O-N 3.09Å
438N39.4Very low35.7Very low102 Ų102102.4 Ų102.455%0.54559%0.585SS.*Hα-helixtrans-56.7-28.3175-69.6-21.9000113.2S434 L442S434-N438 PolarHBondContact O-N 3.08Å; S434-N438 PolarHBondContact O-ND2 2.88Å; N438-L442 PolarHBondContact O-N 3.46Å
439M35.9Very low35.6Very low118 Ų118103.5 Ų103.558%0.58159%0.59SS**Hα-helixtrans-74.8-32.2176.7-171.3172.8-72.600112.3D435 V436 A437 F443D435-M439 PolarHBondContact O-N 3.18Å; V436-M439 WeakPolarHBondContact O-CB 3.44Å; V436-M439 PolarHBondContact O-N 3.24Å; A437-M439 PolarHBondContact O-N 3.2Å; A437-M439 VanDerWaalsContact O-N 3.1Å; M439-F443 HydrophobicContact CG-CE2 4.24Å; M439-F443 WeakPolarHBondContact O-CD2 3.18Å
440F34.5Very low35.3Very low106 Ų106103.5 Ų103.547%0.46560%0.601SS.*Hα-helixtrans-73.7-39.9173.1-81.9-75.3000112.4V436 A437 L442 F443 E444V436-F440 HydrophobicContact CG1-CD2 4.28Å; V436-F440 HydrophobicContact CG1-CE2 4.04Å; V436-F440 WeakPolarHBondContact O-CD2 3.22Å; V436-F440 PolarHBondContact O-N 3.09Å; A437-F440 PolarHBondContact O-N 3.33Å; F440-L442 PolarHBondContact O-N 3.28Å; F440-F443 PolarHBondContact O-N 2.95Å; F440-E444 PolarHBondContact O-N 3.18Å
441D36.9Very low35Very low103 Ų103105 Ų10555%0.55161%0.608SS**Hα-helixtrans-56.8-34.9173.7-65.3-22.8000111.7A437 F443A437-D441 PolarHBondContact O-N 3.21Å; A437-D441 VanDerWaalsContact O-N 3.09Å; D441-F443 VanDerWaalsContact C-N 3.28Å; D441-F443 PolarHBondContact O-N 3.35Å
442L34.6Very low34.6Very low130 Ų130104.1 Ų104.168%0.68161%0.611SS**Hα-helixtrans-69.3-22.4176.6-148.480.1000113.6N438 F440N438-L442 PolarHBondContact O-N 3.46Å; F440-L442 PolarHBondContact O-N 3.28Å
443F33.2Very low34.3Very low140 Ų140111.8 Ų111.861%0.61463%0.634SS**Hα-helixtrans-82.6-40.9176.5-81.4-69.3000112.4M439 F440 D441 A445 T446M439-F443 HydrophobicContact CG-CE2 4.24Å; M439-F443 WeakPolarHBondContact O-CD2 3.18Å; F440-F443 PolarHBondContact O-N 2.95Å; D441-F443 VanDerWaalsContact C-N 3.28Å; D441-F443 PolarHBondContact O-N 3.35Å; F443-A445 PolarHBondContact O-N 2.87Å; F443-T446 PolarHBondContact O-N 3.07Å; F443-T446 PolarHBondContact O-OG1 2.78Å
444E34.9Very low34Very low121 Ų121113.6 Ų113.657%0.56565%0.653SS**Hα-helixtrans-59.4-29.1175.9-74.3-156.9148.900112.2F440 T446 M475F440-E444 PolarHBondContact O-N 3.18Å; E444-T446 PolarHBondContact O-N 2.75Å; E444-T446 VanDerWaalsContact O-N 3.14Å; E444-M475 HydrophobicContact CG-CE 3.56Å; E444-M475 WeakPolarHBondContact OE1-CE 3.24Å
445A34.8Very low33.4Very low83 Ų83121.2 Ų121.269%0.68667%0.671SS**THydrogen-bonded Turntrans-67.1-6.1176.100000115.4F443F443-A445 PolarHBondContact O-N 2.87Å
446T36.4Very low32.9Very low103 Ų103122.3 Ų122.363%0.63268%0.677SS**THydrogen-bonded Turntrans-98.9-14.7-172.761.40000115.9F443 E444F443-T446 PolarHBondContact O-N 3.07Å; F443-T446 PolarHBondContact O-OG1 2.78Å; E444-T446 PolarHBondContact O-N 2.75Å; E444-T446 VanDerWaalsContact O-N 3.14Å
447D34.3Very low32.7Very low148 Ų148128.7 Ų128.779%0.79170%0.703SS**SBendtrans-88.2108.4171.6-93.9-38.7000110.7L449D447-L449 PolarHBondContact O-N 2.78Å
448G27.5Very low32.2Very low82 Ų82131.9 Ų131.985%0.84572%0.718SS**  trans-72.870-161.600000117.6
449L28.2Very low31.6Very low160 Ų160135.1 Ų135.184%0.83874%0.735SS**  trans-125.7123.7166.8-93.6156.2000110.4D447D447-L449 PolarHBondContact O-N 2.78Å
450P28.9Very low31.2Very low113 Ų113135.5 Ų135.573%0.73474%0.744SS**PPolyproline II helixtrans-73142.9-178.129.8-34.7000111.6
451P31.5Very low30.9Very low115 Ų115136.4 Ų136.475%0.74776%0.758SS**PPolyproline II helixtrans-65.5141.4177.526.8-34.4000111.4
452P30.4Very low30.6Very low128 Ų128137.9 Ų137.983%0.83177%0.771SS**PPolyproline II helixtrans-67.4135.817628.1-33.5000110.5A454P452-A454 PolarHBondContact O-N 2.89Å
453R27.1Very low30.2Very low246 Ų246137.6 Ų137.693%0.92878%0.78SS**PPolyproline II helixtrans-66116.4178.1-68.5177.8177165.1-2.4110.7
454A31.4Very low30Very low99 Ų99135.4 Ų135.482%0.81879%0.788SS**PPolyproline II helixtrans-66.3146.4157.600000109.6P452P452-A454 PolarHBondContact O-N 2.89Å
455Y28.6Very low29.6Very low234 Ų234135.1 Ų135.192%0.91881%0.806SS**PPolyproline II helixtrans-87.1145.1174.8-126.7-93.4000110.3
456D26.9Very low29.2Very low132 Ų132136.3 Ų136.371%0.70681%0.81SS**PPolyproline II helixtrans-80.9128.9-172.6-153.3-12.8000111.6
457Q32.3Very low28.8Very low192 Ų192138.2 Ų138.290%0.89782%0.821SS**  trans-156.3101.3157.2-121.917227.300110
458T27.3Very low28.4Very low115 Ų115134.5 Ų134.571%0.70682%0.818SS**  trans-74.5133.4176.853.20000111.6
459D28.1Very low28.3Very low169 Ų169142 Ų14290%0.90482%0.821SS**  trans-149.9136140.2-109.3-33.8000110.7
460T26.3Very low28.2Very low126 Ų126142.9 Ų142.977%0.77382%0.823SS**  trans-97.3143.3-175.853.40000111.5
461V29.8Very low28.1Very low126 Ų126143.9 Ų143.976%0.76483%0.827SS**  trans-172.9127.7134133.80000113.9
462T30.4Very low27.9Very low134 Ų134143.2 Ų143.282%0.82282%0.821SS**  trans59.1145.9161.854.80000121.8
463S25.8Very low27.8Very low123 Ų123140.5 Ų140.586%0.8681%0.805SS**  trans-90.3135.3-179.354.70000113.9
464A28.5Very low27.8Very low94 Ų94136.2 Ų136.278%0.77780%0.796SS**  trans-132135.1152.500000108.3S466A464-S466 PolarHBondContact O-N 3.02Å; A464-S466 VanDerWaalsContact O-N 3.09Å
465A26.3Very low27.7Very low115 Ų115134.7 Ų134.795%0.9577%0.773SS**  trans-77.197.7-175.200000111.1
466S27.7Very low27.7Very low109 Ų109128.3 Ų128.376%0.76275%0.754SS**  trans-93.5132.3170.753.60000110.9A464 G468A464-S466 PolarHBondContact O-N 3.02Å; A464-S466 VanDerWaalsContact O-N 3.09Å; S466-G468 PolarHBondContact O-N 3.06Å; S466-G468 VanDerWaalsContact O-N 3.08Å
467T28Very low27.7Very low142 Ų142128 Ų12887%0.87175%0.747SS**  trans-73.298.9175.134.20000110R469T467-R469 PolarHBondContact O-N 2.88Å
468G26.1Very low27.5Very low71 Ų71121.6 Ų121.673%0.73273%0.732SS**  trans-60.3101.6-179.900000112.5S466 M470S466-G468 PolarHBondContact O-N 3.06Å; S466-G468 VanDerWaalsContact O-N 3.08Å; G468-M470 VanDerWaalsContact C-N 3.32Å; G468-M470 PolarHBondContact O-N 3.18Å
469R25.1Very low27.7Very low239 Ų239121.1 Ų121.190%0.90272%0.721SS**  trans-76.681.1176.7-169.6179.8-171172.33110T467 T471T467-R469 PolarHBondContact O-N 2.88Å; R469-T471 PolarHBondContact O-N 3.15Å
470M25.6Very low27.7Very low179 Ų179117.1 Ų117.188%0.88270%0.702SS**PPolyproline II helixtrans-52.3128.5175.5-82.9178.9157.100111.2G468G468-M470 VanDerWaalsContact C-N 3.32Å; G468-M470 PolarHBondContact O-N 3.18Å
471T27.4Very low27.8Very low134 Ų134113.7 Ų113.782%0.82268%0.681SS**PPolyproline II helixtrans-86.4120.7178.649.10000110.1R469 S473R469-T471 PolarHBondContact O-N 3.15Å; T471-S473 PolarHBondContact O-N 3.24Å
472T26.6Very low27.8Very low100 Ų100112.7 Ų112.761%0.61367%0.671SS**PPolyproline II helixtrans-60.8121.8177.648.40000112.1
473S28.7Very low27.7Very low72 Ų72110.9 Ų110.950%0.50366%0.655SS.*PPolyproline II helixtrans-83.9141.8168.246.30000111.1T471 M475T471-S473 PolarHBondContact O-N 3.24Å; S473-M475 PolarHBondContact O-N 2.94Å
474E27Very low28Very low156 Ų156109.5 Ų109.573%0.72965%0.645SS**  trans-81.895.4171.3-76.2-173.2125.400110.9N476E474-N476 PolarHBondContact O-N 3.19Å; E474-N476 PolarHBondContact O-ND2 3.25Å
475M29Very low28.2Very low67 Ų67112.6 Ų112.633%0.3364%0.643SS.*  trans-73.9113.4173.5-70.9-172.8171.800111.7E444 S473 F477E444-M475 HydrophobicContact CG-CE 3.56Å; E444-M475 WeakPolarHBondContact OE1-CE 3.24Å; S473-M475 PolarHBondContact O-N 2.94Å; M475-F477 HydrophobicContact CB-CD2 4.49Å; M475-F477 HydrophobicContact CB-CE2 3.86Å; M475-F477 HydrophobicContact CB-CZ 4.37Å; M475-F477 PolarHBondContact O-N 2.95Å; M475-F477 HydrophobicContact SD-CZ 4.43Å
476N28.1Very low28.5Very low99 Ų99117.2 Ų117.253%0.52964%0.642SS.*  trans-98.785.4-174.6-89.2-88.7000112.5Q421 E474 G478Q421-N476 PolarHBondContact NE2-OD1 3.36Å; E474-N476 PolarHBondContact O-N 3.19Å; E474-N476 PolarHBondContact O-ND2 3.25Å; N476-G478 PolarHBondContact O-N 3.43Å
477F28.3Very low28.6Very low126 Ų126113.9 Ų113.955%0.55362%0.618SS**  trans-72.2119174.3-64.4-77.6000111.9M475M475-F477 HydrophobicContact CB-CD2 4.49Å; M475-F477 HydrophobicContact CB-CE2 3.86Å; M475-F477 HydrophobicContact CB-CZ 4.37Å; M475-F477 PolarHBondContact O-N 2.95Å; M475-F477 HydrophobicContact SD-CZ 4.43Å
478G27.8Very low28.8Very low57 Ų57115.9 Ų115.959%0.58862%0.615SS**  trans-127.696.5-179.300000113.1N476N476-G478 PolarHBondContact O-N 3.43Å
479F30.6Very low29.1Very low106 Ų106115.1 Ų115.147%0.46560%0.597SS.*  trans-84.1166.7170.155.2-107.9000112.4L418 C420 V481L418-F479 WeakPolarHBondContact O-CD2 3.27Å; L418-F479 WeakPolarHBondContact O-CE2 3.47Å; C420-F479 HydrophobicContact CB-CD1 4.37Å; C420-F479 HydrophobicContact CB-CE1 3.49Å; C420-F479 VanDerWaalsContact CB-CE1 3.49Å; C420-F479 HydrophobicContact CB-CE2 4.03Å; C420-F479 HydrophobicContact CB-CZ 3.29Å; F479-V481 HydrophobicContact CD2-CG2 3.88Å; F479-V481 HydrophobicContact CE2-CG2 4.06Å
480T28.3Very low29.4Very low84 Ų84109.9 Ų109.952%0.51559%0.586SS.*  trans-136.5113178.8-59.20000110.1K417K417-T480 HydrophobicContact CG-CG2 4.34Å
481V29.7Very low29.7Very low54 Ų54109.1 Ų109.133%0.32758%0.578SS.*  trans-96.4104.8-175.6-169.50000111.2L418 F479 M483L418-V481 HydrophobicContact CB-CG2 4.35Å; L418-V481 HydrophobicContact CD1-CB 4.2Å; L418-V481 HydrophobicContact CD1-CG2 4.37Å; F479-V481 HydrophobicContact CD2-CG2 3.88Å; F479-V481 HydrophobicContact CE2-CG2 4.06Å; V481-M483 HydrophobicContact CG1-CE 3.97Å; V481-M483 HydrophobicContact CG1-CG 4.32Å; V481-M483 PolarHBondContact O-N 2.77Å
482N27.9Very low30Very low105 Ų105106.6 Ų106.656%0.56156%0.563SS**  trans-76.691.1179.4-169.1-8.6000112T415 S484T415-N482 HydrophobicContact CG2-CB 4.42Å; N482-S484 PolarHBondContact O-N 3.47Å
483M30.2Very low30.3Very low96 Ų96104.1 Ų104.147%0.47355%0.547SS..  trans-78.852.8178.6-73.5-77.5-17600113.4V481 E485V481-M483 HydrophobicContact CG1-CE 3.97Å; V481-M483 HydrophobicContact CG1-CG 4.32Å; V481-M483 PolarHBondContact O-N 2.77Å; M483-E485 VanDerWaalsContact C-N 3.34Å; M483-E485 PolarHBondContact O-N 2.88Å
484S31.4Very low30.4Very low95 Ų95104 Ų10466%0.66455%0.546SS*.  trans-71.7-2317959.30000114.1N482 K486N482-S484 PolarHBondContact O-N 3.47Å; S484-K486 PolarHBondContact O-N 2.9Å
485E32.5Very low30.7Very low158 Ų15899 Ų9974%0.73853%0.527SS*.SBendtrans-89106.4-177.6-67.6-157.3139.200114.2M483 C487M483-E485 VanDerWaalsContact C-N 3.34Å; M483-E485 PolarHBondContact O-N 2.88Å; E485-C487 PolarHBondContact O-N 3.19Å
486K32.1Very low30.8Very low213 Ų213100.4 Ų100.493%0.92653%0.534SS*.  trans4.869.9161.8-66.8-179.9-179.3172.50116.1S484 K488S484-K486 PolarHBondContact O-N 2.9Å; K486-K488 PolarHBondContact O-N 2.87Å
487C30.9Very low31Very low38 Ų38103.5 Ų103.526%0.25754%0.543SS..  trans-79.894.1-172.3-150.30000111.5E485 P489 L490 K526E485-C487 PolarHBondContact O-N 3.19Å; C487-P489 VanDerWaalsContact C-N 3.31Å; C487-P489 WeakPolarHBondContact O-CD 3.45Å; C487-P489 VanDerWaalsContact O-N 3.13Å; C487-L490 PolarHBondContact O-N 2.87Å; C487-K526 PolarHBondContact SG-NZ 2.81Å
488K31.9Very low31.3Very low185 Ų18599.5 Ų99.580%0.80453%0.533SS*.THydrogen-bonded Turntrans-45.5-37.9179.6-74.3-175.7177179.20116K486 L490 K491K486-K488 PolarHBondContact O-N 2.87Å; K488-L490 PolarHBondContact O-N 2.84Å; K488-L490 VanDerWaalsContact O-N 3.14Å; K488-K491 PolarHBondContact O-N 2.97Å
489P32.7Very low31.5Very low54 Ų54103.9 Ų103.935%0.35154%0.539SS..Hα-helixtrans-56.2-29-177.9-29.237000115.7C487 K491 T492C487-P489 VanDerWaalsContact C-N 3.31Å; C487-P489 WeakPolarHBondContact O-CD 3.45Å; C487-P489 VanDerWaalsContact O-N 3.13Å; P489-K491 PolarHBondContact O-N 3.05Å; P489-T492 VanDerWaalsContact O-CB 3.31Å; P489-T492 WeakPolarHBondContact O-CB 3.44Å; P489-T492 PolarHBondContact O-N 3.13Å
490L31Very low31.7Very low130 Ų130104.2 Ų104.268%0.68155%0.545SS*.Hα-helixtrans-65.2-24.8178.4-78.7165.9000112.9C487 K488 T492 V493 S494C487-L490 PolarHBondContact O-N 2.87Å; K488-L490 PolarHBondContact O-N 2.84Å; K488-L490 VanDerWaalsContact O-N 3.14Å; L490-T492 VanDerWaalsContact C-N 3.32Å; L490-V493 PolarHBondContact O-N 3.48Å; L490-S494 PolarHBondContact O-N 3.01Å
491K32Very low32Very low163 Ų163108.8 Ų108.871%0.70956%0.558SS**Hα-helixtrans-68.2-30.9171.3-79.1-160.7168.7-162.60112.8K488 P489 V493 S494 T495K488-K491 PolarHBondContact O-N 2.97Å; P489-K491 PolarHBondContact O-N 3.05Å; K491-V493 VanDerWaalsContact C-N 3.34Å; K491-S494 WeakPolarHBondContact CA-OG 3.43Å; K491-S494 PolarHBondContact O-N 3.39Å; K491-S494 PolarHBondContact O-OG 3.1Å; K491-T495 PolarHBondContact O-N 2.64Å; K491-T495 PolarHBondContact O-OG1 2.74Å
492T34.1Very low32Very low81 Ų81109.3 Ų109.350%0.49757%0.574SS.*Hα-helixtrans-65-39.3177.9-52.60000111.1P489 L490 S494 T495 I496P489-T492 VanDerWaalsContact O-CB 3.31Å; P489-T492 WeakPolarHBondContact O-CB 3.44Å; P489-T492 PolarHBondContact O-N 3.13Å; L490-T492 VanDerWaalsContact C-N 3.32Å; T492-S494 PolarHBondContact O-N 3.45Å; T492-T495 WeakPolarHBondContact CA-OG1 3.21Å; T492-T495 PolarHBondContact O-N 2.83Å; T492-T495 PolarHBondContact O-OG1 3.42Å; T492-T495 VanDerWaalsContact O-OG1 3.13Å; T492-I496 HydrophobicContact CG2-CD1 4.09Å; T492-I496 VanDerWaalsContact O-CG1 3.31Å; T492-I496 WeakPolarHBondContact O-CG1 3.3Å; T492-I496 PolarHBondContact O-N 3.32Å
493V32Very low32.1Very low48 Ų48112.2 Ų112.229%0.29159%0.585SS.*Hα-helixtrans-60.6-45.5172.9-176.20000110.7L490 K491 T495 I496 F497 L519L490-V493 PolarHBondContact O-N 3.48Å; K491-V493 VanDerWaalsContact C-N 3.34Å; V493-T495 VanDerWaalsContact C-N 3.3Å; V493-T495 PolarHBondContact O-N 3.08Å; V493-I496 PolarHBondContact O-N 3.1Å; V493-F497 HydrophobicContact CG1-CD2 4.06Å; V493-F497 HydrophobicContact CG1-CE2 3.78Å; V493-F497 VanDerWaalsContact O-CD2 3.24Å; V493-F497 WeakPolarHBondContact O-CD2 3.23Å; V493-F497 PolarHBondContact O-N 2.84Å; V493-L519 HydrophobicContact CG2-CD2 4.12Å
494S31.2Very low32.1Very low68 Ų68113.3 Ų113.348%0.47659%0.592SS.*Hα-helixtrans-67.4-23.817861.70000115L490 K491 T492 A498L490-S494 PolarHBondContact O-N 3.01Å; K491-S494 WeakPolarHBondContact CA-OG 3.43Å; K491-S494 PolarHBondContact O-N 3.39Å; K491-S494 PolarHBondContact O-OG 3.1Å; T492-S494 PolarHBondContact O-N 3.45Å; S494-A498 WeakPolarHBondContact O-CB 3.36Å
495T32.3Very low32Very low53 Ų53113.3 Ų113.333%0.32559%0.592SS.*Hα-helixtrans-85.1-34.7175.828.40000112.3K491 T492 V493 F497 A498 E499K491-T495 PolarHBondContact O-N 2.64Å; K491-T495 PolarHBondContact O-OG1 2.74Å; T492-T495 WeakPolarHBondContact CA-OG1 3.21Å; T492-T495 PolarHBondContact O-N 2.83Å; T492-T495 PolarHBondContact O-OG1 3.42Å; T492-T495 VanDerWaalsContact O-OG1 3.13Å; V493-T495 VanDerWaalsContact C-N 3.3Å; V493-T495 PolarHBondContact O-N 3.08Å; T495-F497 PolarHBondContact O-N 3.45Å; T495-A498 PolarHBondContact O-N 3.04Å; T495-E499 WeakPolarHBondContact CB-OE2 3.43Å; T495-E499 HydrophobicContact CG2-CG 4.31Å; T495-E499 WeakPolarHBondContact CG2-OE2 3.31Å; T495-E499 PolarHBondContact O-N 3.21Å
496I32.3Very low32Very low96 Ų96113.2 Ų113.249%0.49259%0.591SS.*Hα-helixtrans-57.6-38.6170.5-69.3164.8000111T492 V493 A498T492-I496 HydrophobicContact CG2-CD1 4.09Å; T492-I496 VanDerWaalsContact O-CG1 3.31Å; T492-I496 WeakPolarHBondContact O-CG1 3.3Å; T492-I496 PolarHBondContact O-N 3.32Å; V493-I496 PolarHBondContact O-N 3.1Å; I496-A498 VanDerWaalsContact C-N 3.28Å; I496-A498 PolarHBondContact O-N 3.41Å
497F31.6Very low32Very low163 Ų163110.9 Ų110.972%0.71558%0.581SS**Hα-helixtrans-76.7-3.2173.7-73.3-63.1000115.2V493 T495V493-F497 HydrophobicContact CG1-CD2 4.06Å; V493-F497 HydrophobicContact CG1-CE2 3.78Å; V493-F497 VanDerWaalsContact O-CD2 3.24Å; V493-F497 WeakPolarHBondContact O-CD2 3.23Å; V493-F497 PolarHBondContact O-N 2.84Å; T495-F497 PolarHBondContact O-N 3.45Å
498A34.9Very low32.1Very low42 Ų42111.2 Ų111.235%0.34758%0.582SS.*Hα-helixtrans-123.7-29.4-170.800000115.4S494 T495 I496 K501S494-A498 WeakPolarHBondContact O-CB 3.36Å; T495-A498 PolarHBondContact O-N 3.04Å; I496-A498 VanDerWaalsContact C-N 3.28Å; I496-A498 PolarHBondContact O-N 3.41Å; A498-K501 WeakPolarHBondContact O-CE 3.25Å; A498-K501 PolarHBondContact O-NZ 2.99Å
499E33.1Very low32.2Very low149 Ų149107.2 Ų107.270%0.69657%0.574SS**Hα-helixtrans-104.4-29.3-168.3-63.5-173.1133.700114T495 K501T495-E499 WeakPolarHBondContact CB-OE2 3.43Å; T495-E499 HydrophobicContact CG2-CG 4.31Å; T495-E499 WeakPolarHBondContact CG2-OE2 3.31Å; T495-E499 PolarHBondContact O-N 3.21Å; E499-K501 VanDerWaalsContact C-N 3.34Å; E499-K501 PolarHBondContact O-N 2.85Å
500D33.9Very low32.4Very low113 Ų113108.4 Ų108.460%0.60458%0.584SS**  trans-84.877.6173.6-159.5-15.5000111.8G502D500-G502 PolarHBondContact OD1-N 3.38Å
501K33.5Very low32.8Very low180 Ų180105.1 Ų105.178%0.78357%0.571SS**  trans-98.814.8175.4-70.1175.9175.1157.50112.7A498 E499A498-K501 WeakPolarHBondContact O-CE 3.25Å; A498-K501 PolarHBondContact O-NZ 2.99Å; E499-K501 VanDerWaalsContact C-N 3.34Å; E499-K501 PolarHBondContact O-N 2.85Å
502G31.2Very low33Very low65 Ų6598.3 Ų98.367%0.6754%0.543SS*.SBendtrans-93.6-58.1-175.800000113.4D500D500-G502 PolarHBondContact OD1-N 3.38Å
503E29.9Very low33.3Very low166 Ų16696.5 Ų96.578%0.77653%0.534SS*.  trans-120.162-164.5-61.6-165.6143.800112.6S505E503-S505 PolarHBondContact O-N 3.45Å
504L29.4Very low34.1Very low119 Ų119100.7 Ų100.762%0.62355%0.548SS*.  trans-76.152.1179.1-148.283.9000113.4P370P370-L504 HydrophobicContact CG-CD2 4.48Å
505S29.8Very low34.7Very low96 Ų96100.4 Ų100.467%0.67154%0.544SS*.  trans-118.2123.1175.756.10000111.4E503E503-S505 PolarHBondContact O-N 3.45Å
506E31.8Very low35.4Very low155 Ų15598.6 Ų98.672%0.72453%0.532SS*.  trans65.779.6172.4-119.1161.5-122.800115.9T508E506-T508 HydrophobicContact CB-CG2 4.13Å; E506-T508 HydrophobicContact CG-CG2 4.05Å; E506-T508 PolarHBondContact O-N 3.08Å
507F33.3Very low36.2Very low164 Ų16497.5 Ų97.572%0.71953%0.527SS*.  trans-67.372.1164.6-133.1-88.9000110.4V512F507-V512 HydrophobicContact CD1-CG2 3.91Å; F507-V512 HydrophobicContact CE1-CG2 3.86Å
508T33.5Very low37Very low45 Ų4593.7 Ų93.728%0.27651%0.514SS..  trans-72.1154-17757.70000112.2E506 S510 S511 V512E506-T508 HydrophobicContact CB-CG2 4.13Å; E506-T508 HydrophobicContact CG-CG2 4.05Å; E506-T508 PolarHBondContact O-N 3.08Å; T508-S510 WeakPolarHBondContact CB-OG 3.37Å; T508-S510 PolarHBondContact O-N 2.73Å; T508-S510 PolarHBondContact OG1-OG 3.07Å; T508-S511 PolarHBondContact O-N 2.99Å; T508-S511 PolarHBondContact OG1-N 3.38Å; T508-S511 PolarHBondContact OG1-OG 3.45Å; T508-V512 PolarHBondContact O-N 3.15Å
509T33.5Very low37.5Very low101 Ų10194.5 Ų94.562%0.6251%0.512SS*.Hα-helixtrans-57-31.317343.30000112.4V512 S513T509-V512 PolarHBondContact O-N 2.77Å; T509-S513 WeakPolarHBondContact O-CB 3.3Å; T509-S513 PolarHBondContact O-N 3.41Å
510S36.7Very low38.1Very low80 Ų8090.9 Ų90.956%0.55950%0.495SS*.Hα-helixtrans-61.3-40.9171.728.90000113.7T508 S513 K514T508-S510 WeakPolarHBondContact CB-OG 3.37Å; T508-S510 PolarHBondContact O-N 2.73Å; T508-S510 PolarHBondContact OG1-OG 3.07Å; S510-S513 PolarHBondContact O-N 2.9Å; S510-K514 WeakPolarHBondContact O-CB 3.26Å; S510-K514 PolarHBondContact O-N 3.16Å
511S38.1Very low38.8Very low60 Ų6092.7 Ų92.742%0.4249%0.494SS..Hα-helixtrans-67.7-40.9177.7-59.60000111.5T508 K514 V515T508-S511 PolarHBondContact O-N 2.99Å; T508-S511 PolarHBondContact OG1-N 3.38Å; T508-S511 PolarHBondContact OG1-OG 3.45Å; S511-K514 PolarHBondContact O-N 2.84Å; S511-V515 WeakPolarHBondContact O-CG2 3.06Å; S511-V515 PolarHBondContact O-N 3.48Å
512V36.5Very low39.2Very low21 Ų2185.6 Ų85.613%0.12747%0.469CS..Hα-helixtrans-67.4-42.1175.4-179.70000111.2V210 F507 T508 T509 K514 V515 L516V210-V512 HydrophobicContact CB-CG1 4.08Å; V210-V512 HydrophobicContact CG1-CG1 3.96Å; V210-V512 HydrophobicContact CG2-CG1 4.34Å; F507-V512 HydrophobicContact CD1-CG2 3.91Å; F507-V512 HydrophobicContact CE1-CG2 3.86Å; T508-V512 PolarHBondContact O-N 3.15Å; T509-V512 PolarHBondContact O-N 2.77Å; V512-K514 PolarHBondContact O-N 2.88Å; V512-V515 PolarHBondContact O-N 2.75Å; V512-L516 HydrophobicContact CG1-CD1 4.22Å; V512-L516 PolarHBondContact O-N 3.38Å
513S41.3Very low39.6Very low43 Ų4384.7 Ų84.730%0.30146%0.459SS..Hα-helixtrans-57.3-49.4174.7-164.70000110.8T509 S510 V515 L516 D517T509-S513 WeakPolarHBondContact O-CB 3.3Å; T509-S513 PolarHBondContact O-N 3.41Å; S510-S513 PolarHBondContact O-N 2.9Å; S513-V515 VanDerWaalsContact C-N 3.29Å; S513-V515 PolarHBondContact O-N 3.14Å; S513-L516 CarbonylContact O-C 3.47Å; S513-L516 WeakPolarHBondContact O-CA 3.45Å; S513-L516 VanDerWaalsContact O-CB 3.25Å; S513-L516 WeakPolarHBondContact O-CB 3.39Å; S513-L516 PolarHBondContact O-N 3.21Å; S513-D517 PolarHBondContact O-N 3.24Å; S513-D517 VanDerWaalsContact O-OD2 3.1Å
514K47.8Very low39.9Very low135 Ų13582.7 Ų82.759%0.58745%0.445SS*.Hα-helixtrans-59.3-38.7179.6-172.5-173.2172.4-165.60112.6S510 S511 V512 D517 D518S510-K514 WeakPolarHBondContact O-CB 3.26Å; S510-K514 PolarHBondContact O-N 3.16Å; S511-K514 PolarHBondContact O-N 2.84Å; V512-K514 PolarHBondContact O-N 2.88Å; K514-D517 PolarHBondContact O-N 2.91Å; K514-D518 WeakPolarHBondContact O-CB 3.5Å; K514-D518 PolarHBondContact O-N 3.03Å
515V44.9Very low40.2Very low63 Ų6383.8 Ų83.838%0.38244%0.441SS..Hα-helixtrans-69.4-34.7175.8173.60000111.8S511 V512 S513 L519S511-V515 WeakPolarHBondContact O-CG2 3.06Å; S511-V515 PolarHBondContact O-N 3.48Å; V512-V515 PolarHBondContact O-N 2.75Å; S513-V515 VanDerWaalsContact C-N 3.29Å; S513-V515 PolarHBondContact O-N 3.14Å; V515-L519 HydrophobicContact CG1-CD1 4.1Å; V515-L519 WeakPolarHBondContact O-CB 2.89Å; V515-L519 WeakPolarHBondContact O-CD1 3.47Å; V515-L519 WeakPolarHBondContact O-CG 3.46Å; V515-L519 PolarHBondContact O-N 3.15Å; V515-L519 VanDerWaalsContact O-N 3.1Å
516L46.7Very low40.5Very low15 Ų1583.3 Ų83.38%0.07943%0.427CS..Hα-helixtrans-61-52.9167.9-10471.1000110.8F205 V512 S513 D518 L519 E520F205-L516 HydrophobicContact CD1-CD1 3.94Å; F205-L516 HydrophobicContact CD1-CD2 4.41Å; F205-L516 HydrophobicContact CD1-CG 3.87Å; F205-L516 HydrophobicContact CE1-CD1 3.37Å; F205-L516 HydrophobicContact CE1-CG 3.64Å; F205-L516 HydrophobicContact CZ-CD1 3.8Å; F205-L516 WeakPolarHBondContact O-CD2 3.47Å; V512-L516 HydrophobicContact CG1-CD1 4.22Å; V512-L516 PolarHBondContact O-N 3.38Å; S513-L516 CarbonylContact O-C 3.47Å; S513-L516 WeakPolarHBondContact O-CA 3.45Å; S513-L516 VanDerWaalsContact O-CB 3.25Å; S513-L516 WeakPolarHBondContact O-CB 3.39Å; S513-L516 PolarHBondContact O-N 3.21Å; L516-D518 VanDerWaalsContact C-N 3.33Å; L516-D518 PolarHBondContact O-N 3.09Å; L516-L519 WeakPolarHBondContact O-CB 3.36Å; L516-L519 PolarHBondContact O-N 3.33Å; L516-E520 PolarHBondContact O-N 3Å
517D48.9Very low40.6Very low72 Ų7277.8 Ų77.839%0.38541%0.408SS..Hα-helixtrans-56.5-46.6-179.3-57.5-38.7000110.8S513 K514 L519 E520 W521S513-D517 PolarHBondContact O-N 3.24Å; S513-D517 VanDerWaalsContact O-OD2 3.1Å; K514-D517 PolarHBondContact O-N 2.91Å; D517-L519 VanDerWaalsContact C-N 3.33Å; D517-L519 PolarHBondContact O-N 3.26Å; D517-E520 PolarHBondContact O-N 3.38Å; D517-W521 VanDerWaalsContact O-CB 3.29Å; D517-W521 WeakPolarHBondContact O-CB 3.39Å; D517-W521 VanDerWaalsContact O-CD1 3.24Å; D517-W521 PolarHBondContact O-N 3.38Å
518D49.4Very low40.6Very low84 Ų8472.7 Ų72.745%0.44939%0.39SS..Hα-helixtrans-65.1-33177.8-85.1-41000112.6K514 L516 A522K514-D518 WeakPolarHBondContact O-CB 3.5Å; K514-D518 PolarHBondContact O-N 3.03Å; L516-D518 VanDerWaalsContact C-N 3.33Å; L516-D518 PolarHBondContact O-N 3.09Å; D518-A522 VanDerWaalsContact O-CB 3.26Å; D518-A522 WeakPolarHBondContact O-CB 3.24Å; D518-A522 PolarHBondContact O-N 3.19Å
519L45.1Very low40.6Very low58 Ų5873.7 Ų73.730%0.30440%0.399SS..Hα-helixtrans-74.1-43.6175.2-76.9169.3000112.2F205 V493 V515 L516 D517 A522 G523F205-L519 HydrophobicContact CE1-CD1 4.13Å; F205-L519 HydrophobicContact CZ-CD1 4.27Å; V493-L519 HydrophobicContact CG2-CD2 4.12Å; V515-L519 HydrophobicContact CG1-CD1 4.1Å; V515-L519 WeakPolarHBondContact O-CB 2.89Å; V515-L519 WeakPolarHBondContact O-CD1 3.47Å; V515-L519 WeakPolarHBondContact O-CG 3.46Å; V515-L519 PolarHBondContact O-N 3.15Å; V515-L519 VanDerWaalsContact O-N 3.1Å; L516-L519 WeakPolarHBondContact O-CB 3.36Å; L516-L519 PolarHBondContact O-N 3.33Å; D517-L519 VanDerWaalsContact C-N 3.33Å; D517-L519 PolarHBondContact O-N 3.26Å; L519-A522 WeakPolarHBondContact O-CB 3.36Å; L519-A522 PolarHBondContact O-N 3.15Å; L519-G523 PolarHBondContact O-N 3.29Å
520E44.3Very low40.6Very low74 Ų7474.6 Ų74.635%0.34640%0.399SS..Hα-helixtrans-63.1-44.3173.6-70.8-170.817100110.6L516 D517 A522 G523 Y524L516-E520 PolarHBondContact O-N 3Å; D517-E520 PolarHBondContact O-N 3.38Å; E520-A522 VanDerWaalsContact C-N 3.29Å; E520-A522 PolarHBondContact O-N 3.37Å; E520-G523 PolarHBondContact O-N 2.99Å; E520-Y524 WeakPolarHBondContact O-CB 3.11Å; E520-Y524 PolarHBondContact O-N 3.47Å
521W48.8Very low40.4Very low150 Ų15074.9 Ų74.957%0.56839%0.391SS*.Hα-helixtrans-66-25.2172.7-86.8104.5000113.9D517 Y524 R525D517-W521 VanDerWaalsContact O-CB 3.29Å; D517-W521 WeakPolarHBondContact O-CB 3.39Å; D517-W521 VanDerWaalsContact O-CD1 3.24Å; D517-W521 PolarHBondContact O-N 3.38Å; W521-Y524 HydrophobicContact CE3-CD1 4.1Å; W521-Y524 AromaticContact CZ3-CD1 3.82Å; W521-Y524 HydrophobicContact CZ3-CD1 3.82Å; W521-Y524 HydrophobicContact CZ3-CE1 4.18Å; W521-R525 VanDerWaalsContact O-CB 3.25Å; W521-R525 WeakPolarHBondContact O-CB 3.38Å; W521-R525 VanDerWaalsContact O-CG 3.25Å; W521-R525 WeakPolarHBondContact O-CG 3.49Å; W521-R525 PolarHBondContact O-N 3.12Å; W521-R525 VanDerWaalsContact O-N 3.11Å; W521-R525 PolarHBondContact O-NE 2.88Å
522A41.6Very low40.1Very low32 Ų3274.7 Ų74.726%0.26440%0.398SS..Hα-helixtrans-73.6-41.2170.700000111.4D518 L519 E520 K526D518-A522 VanDerWaalsContact O-CB 3.26Å; D518-A522 WeakPolarHBondContact O-CB 3.24Å; D518-A522 PolarHBondContact O-N 3.19Å; L519-A522 WeakPolarHBondContact O-CB 3.36Å; L519-A522 PolarHBondContact O-N 3.15Å; E520-A522 VanDerWaalsContact C-N 3.29Å; E520-A522 PolarHBondContact O-N 3.37Å; A522-K526 PolarHBondContact O-N 3.12Å
523G39.3Very low39.9Very low45 Ų4578.7 Ų78.746%0.46442%0.423SS..Hα-helixtrans-60.1-53.317200000112L519 E520 R525 K526 A527L519-G523 PolarHBondContact O-N 3.29Å; E520-G523 PolarHBondContact O-N 2.99Å; G523-R525 PolarHBondContact O-N 3.45Å; G523-K526 PolarHBondContact O-N 2.76Å; G523-A527 PolarHBondContact O-N 2.71Å
524Y37.8Very low39.6Very low124 Ų12479.3 Ų79.349%0.48643%0.431SS..Hα-helixtrans-59.6-42179.3-172.7-93.9000112.6E520 W521 K526 A527 T528E520-Y524 WeakPolarHBondContact O-CB 3.11Å; E520-Y524 PolarHBondContact O-N 3.47Å; W521-Y524 HydrophobicContact CE3-CD1 4.1Å; W521-Y524 AromaticContact CZ3-CD1 3.82Å; W521-Y524 HydrophobicContact CZ3-CD1 3.82Å; W521-Y524 HydrophobicContact CZ3-CE1 4.18Å; Y524-K526 VanDerWaalsContact C-N 3.34Å; Y524-K526 PolarHBondContact O-N 2.78Å; Y524-A527 PolarHBondContact O-N 3.46Å; Y524-T528 HydrophobicContact CD1-CG2 4.17Å; Y524-T528 HydrophobicContact CE1-CG2 3.69Å; Y524-T528 HydrophobicContact CE2-CG2 4.39Å; Y524-T528 PolarHBondContact O-N 3.49Å; Y524-T528 PolarHBondContact O-OG1 3.25Å
525R35Very low38.9Very low143 Ų14382.3 Ų82.354%0.5444%0.444SS..Hα-helixtrans-65.5-32.1173.7-79.5-179.4-71.1-175.3-4.5113.2W521 G523 T528 S529W521-R525 VanDerWaalsContact O-CB 3.25Å; W521-R525 WeakPolarHBondContact O-CB 3.38Å; W521-R525 VanDerWaalsContact O-CG 3.25Å; W521-R525 WeakPolarHBondContact O-CG 3.49Å; W521-R525 PolarHBondContact O-N 3.12Å; W521-R525 VanDerWaalsContact O-N 3.11Å; W521-R525 PolarHBondContact O-NE 2.88Å; G523-R525 PolarHBondContact O-N 3.45Å; R525-T528 WeakPolarHBondContact CA-OG1 3.47Å; R525-T528 PolarHBondContact O-OG1 2.91Å; R525-S529 VanDerWaalsContact O-CB 3.31Å; R525-S529 WeakPolarHBondContact O-CB 3.36Å; R525-S529 PolarHBondContact O-N 2.89Å; R525-S529 VanDerWaalsContact O-N 3.07Å; R525-S529 PolarHBondContact O-OG 3.01Å
526K36.8Very low38.2Very low86 Ų8683.3 Ų83.337%0.37446%0.459SS..Hα-helixtrans-73.7-38175.6-157.5-174.8-179.2-162.10111.6C487 A522 G523 Y524 S529C487-K526 PolarHBondContact SG-NZ 2.81Å; A522-K526 PolarHBondContact O-N 3.12Å; G523-K526 PolarHBondContact O-N 2.76Å; Y524-K526 VanDerWaalsContact C-N 3.34Å; Y524-K526 PolarHBondContact O-N 2.78Å; K526-S529 PolarHBondContact O-OG 2.79Å
527A33.4Very low37.2Very low38 Ų3889.6 Ų89.631%0.31449%0.492SS..Hα-helixtrans-64.6-50.3173.700000111.7G523 Y524 S529 L530 F531G523-A527 PolarHBondContact O-N 2.71Å; Y524-A527 PolarHBondContact O-N 3.46Å; A527-S529 VanDerWaalsContact C-N 3.34Å; A527-S529 PolarHBondContact O-N 2.86Å; A527-L530 PolarHBondContact O-N 3.1Å; A527-F531 PolarHBondContact O-N 3.2Å
528T33.8Very low36.3Very low57 Ų5797.7 Ų97.735%0.3552%0.517SS..Hα-helixtrans-67.4-28.3-179.948.30000113.8Y524 R525 L530 F531 G532Y524-T528 HydrophobicContact CD1-CG2 4.17Å; Y524-T528 HydrophobicContact CE1-CG2 3.69Å; Y524-T528 HydrophobicContact CE2-CG2 4.39Å; Y524-T528 PolarHBondContact O-N 3.49Å; Y524-T528 PolarHBondContact O-OG1 3.25Å; R525-T528 WeakPolarHBondContact CA-OG1 3.47Å; R525-T528 PolarHBondContact O-OG1 2.91Å; T528-L530 VanDerWaalsContact C-N 3.33Å; T528-L530 PolarHBondContact O-N 2.87Å; T528-F531 PolarHBondContact O-N 3.04Å; T528-G532 PolarHBondContact O-N 3.07Å
529S32.9Very low35.4Very low66 Ų66102.1 Ų102.146%0.46254%0.535SS..Hα-helixtrans-68.6-29.7175.170.40000113.5R525 K526 A527 G532 T533R525-S529 VanDerWaalsContact O-CB 3.31Å; R525-S529 WeakPolarHBondContact O-CB 3.36Å; R525-S529 PolarHBondContact O-N 2.89Å; R525-S529 VanDerWaalsContact O-N 3.07Å; R525-S529 PolarHBondContact O-OG 3.01Å; K526-S529 PolarHBondContact O-OG 2.79Å; A527-S529 VanDerWaalsContact C-N 3.34Å; A527-S529 PolarHBondContact O-N 2.86Å; S529-G532 PolarHBondContact O-N 2.9Å; S529-T533 PolarHBondContact O-N 2.98Å; S529-T533 PolarHBondContact O-OG1 3.29Å
530L32.7Very low34.5Very low120 Ų120105.6 Ų105.663%0.62856%0.558SS**Hα-helixtrans-71.2-33.2172.8-72.3161.9000112.3A527 T528 T533A527-L530 PolarHBondContact O-N 3.1Å; T528-L530 VanDerWaalsContact C-N 3.33Å; T528-L530 PolarHBondContact O-N 2.87Å; L530-T533 PolarHBondContact O-OG1 2.91Å
531F32.7Very low33.9Very low87 Ų87107.6 Ų107.638%0.38258%0.578SS.*Hα-helixtrans-69.8-39.6170.1-85.5-82.3000112.6A527 T528 T533 A534 M579A527-F531 PolarHBondContact O-N 3.2Å; T528-F531 PolarHBondContact O-N 3.04Å; F531-T533 PolarHBondContact O-N 3.03Å; F531-A534 PolarHBondContact O-N 3.34Å; F531-M579 WeakPolarHBondContact CE1-O 3.41Å; F531-M579 HydrophobicContact CE2-CB 3.94Å; F531-M579 HydrophobicContact CE2-CG 3.91Å; F531-M579 HydrophobicContact CE2-SD 3.75Å; F531-M579 HydrophobicContact CZ-CB 3.76Å; F531-M579 HydrophobicContact CZ-CG 3.82Å; F531-M579 WeakPolarHBondContact CZ-O 3.15Å; F531-M579 HydrophobicContact CZ-SD 4.27Å
532G32.7Very low32.8Very low56 Ų56105.7 Ų105.758%0.57759%0.587SS**Hα-helixtrans-61.9-39.1-177.200000113.8T528 S529T528-G532 PolarHBondContact O-N 3.07Å; S529-G532 PolarHBondContact O-N 2.9Å
533T32.5Very low32.2Very low104 Ų104112.3 Ų112.364%0.63861%0.613SS**Hα-helixtrans-76.6-25.7-179.1510000113.6S529 L530 F531 K535S529-T533 PolarHBondContact O-N 2.98Å; S529-T533 PolarHBondContact O-OG1 3.29Å; L530-T533 PolarHBondContact O-OG1 2.91Å; F531-T533 PolarHBondContact O-N 3.03Å; T533-K535 PolarHBondContact O-N 3.29Å
534A33.6Very low31.7Very low56 Ų56116.6 Ų116.646%0.46363%0.63SS.*Hα-helixtrans-66.4-19.7178.900000114.2F531 A536F531-A534 PolarHBondContact O-N 3.34Å; A534-A536 VanDerWaalsContact C-N 3.26Å; A534-A536 PolarHBondContact O-N 3.37Å
535K33.6Very low31Very low198 Ų198116.1 Ų116.186%0.86164%0.642SS**THydrogen-bonded Turntrans-77.7-3.1-174.1-157.8167.6-176.5174.10114.7T533T533-K535 PolarHBondContact O-N 3.29Å
536A30.1Very low30.6Very low85 Ų85119.6 Ų119.670%0.70266%0.661SS**THydrogen-bonded Turntrans-95-4-174.300000115.4A534A534-A536 VanDerWaalsContact C-N 3.26Å; A534-A536 PolarHBondContact O-N 3.37Å
537L27.1Very low30.2Very low147 Ų147122.9 Ų122.977%0.7768%0.678SS**SBendtrans-136.389.2-168.4-75.3171.1000114.3
538R28.6Very low29.8Very low241 Ų241127.3 Ų127.391%0.90970%0.697SS**  trans154.3135.5135.4-83.8165.2-168.8-156.71.3110.7
539Q30.7Very low29.4Very low178 Ų178129.8 Ų129.883%0.83272%0.716SS**  trans-111.4131.8-177.5-62.3164.1-63.400109.5
540T25.6Very low29.1Very low130 Ų130134.8 Ų134.880%0.79873%0.732SS**  trans53.2162.7132.563.10000122
541P33.3Very low29Very low117 Ų117137.1 Ų137.176%0.7674%0.737SS**  cis-140.5-153.3-44.542.2-24.2000112
542S24.6Very low29.1Very low109 Ų109140.1 Ų140.176%0.76276%0.758SS**  trans84.5140177.9-130.30000114.4
543E28.5Very low30.1Very low172 Ų172141.2 Ų141.280%0.80475%0.753SS**  cis-132.2154.119.2-73.9-179.3145.200115.3
544V29Very low30.4Very low135 Ų135142.4 Ų142.482%0.81876%0.755SS**  trans38.1129152.8-171.80000121.6
545P24.8Very low30.9Very low114 Ų114142 Ų14274%0.7476%0.756SS**  trans-98.9171.3179.340.3-36.6000115.6
546F25.6Very low31.6Very low216 Ų216135.2 Ų135.295%0.94774%0.737SS**  trans-122.9147.1161.6-131.8-94.3000109.3
547E28.5Very low32.6Very low155 Ų155135.8 Ų135.872%0.72473%0.727SS**  trans-103.3143.3-163.5-88.5-162.9113.900116.3
548N25Very low33.9Very low131 Ų131133.7 Ų133.770%0.70172%0.717SS**  trans51.197.1141.1-52.6-28.3000120.2
549S25.3Very low35.4Very low109 Ų109126.2 Ų126.276%0.76270%0.695SS**  -174145.2110.561.50000113.8
550E26.8Very low36.5Very low170 Ų170120.7 Ų120.779%0.79467%0.667SS**  trans69.8157.7166.7-55.1-165.713400118.7
551F30.1Very low38Very low169 Ų169116.4 Ų116.474%0.74164%0.642SS**  trans65.8106.4-179.3-66.7-82.9000118.8T553F551-T553 HydrophobicContact CB-CG2 3.91Å; F551-T553 HydrophobicContact CD1-CG2 4.28Å; F551-T553 HydrophobicContact CG-CG2 4.43Å; F551-T553 PolarHBondContact O-N 3.29Å; F551-T553 PolarHBondContact O-OG1 2.64Å
552D35.7Very low39.6Very low151 Ų151120.2 Ų120.281%0.80764%0.641SS**  trans-67.629.4164.2-98.8-48.7000113.8L554 G555 A556D552-L554 PolarHBondContact O-N 2.93Å; D552-G555 PolarHBondContact O-N 2.82Å; D552-A556 WeakPolarHBondContact O-CB 3.36Å; D552-A556 PolarHBondContact O-N 3Å
553T52.3Low41.6Very low79 Ų79122 Ų12249%0.48564%0.635SS.*Hα-helixtrans-57.5-47-163.728.60000114F551 G555 A556 I557F551-T553 HydrophobicContact CB-CG2 3.91Å; F551-T553 HydrophobicContact CD1-CG2 4.28Å; F551-T553 HydrophobicContact CG-CG2 4.43Å; F551-T553 PolarHBondContact O-N 3.29Å; F551-T553 PolarHBondContact O-OG1 2.64Å; T553-G555 VanDerWaalsContact C-N 3.34Å; T553-G555 PolarHBondContact O-N 2.83Å; T553-A556 PolarHBondContact O-N 2.93Å; T553-I557 WeakPolarHBondContact O-CB 3.27Å; T553-I557 WeakPolarHBondContact O-CD1 3.48Å; T553-I557 WeakPolarHBondContact O-CG1 3.2Å; T553-I557 PolarHBondContact O-N 2.77Å
554L40Very low43.1Very low128 Ų128117.5 Ų117.567%0.6761%0.614SS**Hα-helixtrans-66.7-37.2-177.6-163.274.8000112.3D552 L558D552-L554 PolarHBondContact O-N 2.93Å; L554-L558 HydrophobicContact CG-CD1 4.48Å; L554-L558 WeakPolarHBondContact O-CB 3.48Å; L554-L558 PolarHBondContact O-N 2.97Å; L554-L558 VanDerWaalsContact O-N 3.08Å
555G44.2Very low44.7Very low48 Ų48118 Ų11850%0.49561%0.612SS.*Hα-helixtrans-67.9-42.1174.600000111.9D552 T553 N559D552-G555 PolarHBondContact O-N 2.82Å; T553-G555 VanDerWaalsContact C-N 3.34Å; T553-G555 PolarHBondContact O-N 2.83Å; G555-N559 WeakPolarHBondContact O-CB 3.18Å; G555-N559 PolarHBondContact O-N 3.09Å; G555-N559 VanDerWaalsContact O-N 3.09Å
556A49Very low46.2Very low55 Ų55114.2 Ų114.246%0.45559%0.59SS.*Hα-helixtrans-61.5-48.5173.800000111.8D552 T553 L558 N559 Y560D552-A556 WeakPolarHBondContact O-CB 3.36Å; D552-A556 PolarHBondContact O-N 3Å; T553-A556 PolarHBondContact O-N 2.93Å; A556-L558 PolarHBondContact O-N 3.22Å; A556-N559 CarbonylContact O-C 3.54Å; A556-N559 WeakPolarHBondContact O-CB 3.35Å; A556-N559 PolarHBondContact O-N 3.41Å; A556-N559 VanDerWaalsContact O-N 3.09Å; A556-Y560 WeakPolarHBondContact O-CB 3.46Å; A556-Y560 PolarHBondContact O-N 3.45Å
557I50.7Low47.8Very low97 Ų97110.3 Ų110.350%0.49758%0.579SS.*Hα-helixtrans-59-47.3179-71161.9000111.1T553 N559 Y560 S561T553-I557 WeakPolarHBondContact O-CB 3.27Å; T553-I557 WeakPolarHBondContact O-CD1 3.48Å; T553-I557 WeakPolarHBondContact O-CG1 3.2Å; T553-I557 PolarHBondContact O-N 2.77Å; I557-N559 PolarHBondContact O-N 3.07Å; I557-Y560 WeakPolarHBondContact O-CB 3.28Å; I557-Y560 PolarHBondContact O-N 3.31Å; I557-Y560 VanDerWaalsContact O-N 3.15Å; I557-S561 PolarHBondContact O-N 2.76Å; I557-S561 PolarHBondContact O-OG 3.28Å
558L54.6Low48.5Very low104 Ų104106 Ų10655%0.54556%0.559SS.*Hα-helixtrans-67.5-22.1177-78.1168.7000113.9L554 A556 R562L554-L558 HydrophobicContact CG-CD1 4.48Å; L554-L558 WeakPolarHBondContact O-CB 3.48Å; L554-L558 PolarHBondContact O-N 2.97Å; L554-L558 VanDerWaalsContact O-N 3.08Å; A556-L558 PolarHBondContact O-N 3.22Å; L558-R562 WeakPolarHBondContact O-CD 3.35Å; L558-R562 VanDerWaalsContact O-CG 3.26Å; L558-R562 WeakPolarHBondContact O-CG 3.49Å
559N59.3Low49.8Very low84 Ų84101.9 Ų101.945%0.44954%0.544SS..Hα-helixtrans-83.7-33172.4-160.15.7000111G555 A556 I557 K563G555-N559 WeakPolarHBondContact O-CB 3.18Å; G555-N559 PolarHBondContact O-N 3.09Å; G555-N559 VanDerWaalsContact O-N 3.09Å; A556-N559 CarbonylContact O-C 3.54Å; A556-N559 WeakPolarHBondContact O-CB 3.35Å; A556-N559 PolarHBondContact O-N 3.41Å; A556-N559 VanDerWaalsContact O-N 3.09Å; I557-N559 PolarHBondContact O-N 3.07Å; N559-K563 WeakPolarHBondContact O-CD 3.41Å; N559-K563 VanDerWaalsContact O-CG 3.29Å; N559-K563 WeakPolarHBondContact O-CG 3.39Å; N559-K563 PolarHBondContact O-N 2.92Å; N559-K563 WeakPolarHBondContact OD1-CE 3.3Å; N559-K563 PolarHBondContact OD1-NZ 2.98Å
560Y54.7Low51Low62 Ų62101.9 Ų101.924%0.24353%0.528CS..Hα-helixtrans-69.2-53177.4-156.6-89.7000111.1A556 I557 R562 K563 H564 F585 G586A556-Y560 WeakPolarHBondContact O-CB 3.46Å; A556-Y560 PolarHBondContact O-N 3.45Å; I557-Y560 WeakPolarHBondContact O-CB 3.28Å; I557-Y560 PolarHBondContact O-N 3.31Å; I557-Y560 VanDerWaalsContact O-N 3.15Å; Y560-R562 PolarHBondContact O-N 2.83Å; Y560-K563 PolarHBondContact O-N 3.18Å; Y560-H564 HydrophobicContact CD1-CB 4.03Å; Y560-H564 AromaticContact CD1-CD2 3.68Å; Y560-H564 AromaticContact CD1-CG 3.91Å; Y560-H564 AromaticContact CD2-CD2 3.63Å; Y560-H564 AromaticContact CD2-NE2 3.75Å; Y560-H564 HydrophobicContact CE1-CB 3.79Å; Y560-H564 AromaticContact CE1-CD2 3.63Å; Y560-H564 AromaticContact CE1-CG 3.53Å; Y560-H564 AromaticContact CE2-CD2 3.58Å; Y560-H564 AromaticContact CE2-CE1 3.83Å; Y560-H564 AromaticContact CE2-NE2 3.42Å; Y560-H564 WeakPolarHBondContact CE2-NE2 3.3Å; Y560-H564 AromaticContact CG-CD2 3.68Å; Y560-H564 AromaticContact CZ-CD2 3.58Å; Y560-H564 AromaticContact CZ-CE1 3.74Å; Y560-H564 AromaticContact CZ-CG 3.66Å; Y560-H564 AromaticContact CZ-ND1 3.74Å; Y560-H564 AromaticContact CZ-NE2 3.7Å; Y560-H564 PolarHBondContact O-CD2 3.14Å; Y560-H564 PolarHBondContact O-N 2.93Å; Y560-F585 HydrophobicContact CD1-CB 4.08Å; Y560-F585 HydrophobicContact CD1-CD1 4.47Å; Y560-F585 HydrophobicContact CD1-CG 4.34Å; Y560-F585 HydrophobicContact CE1-CB 3.93Å; Y560-G586 PolarHBondContact OH-O 3.38Å
561S55.3Low53Low40 Ų4099.6 Ų99.628%0.2851%0.513SS..THydrogen-bonded Turntrans-65.4-11.3177.6630000114.5I557I557-S561 PolarHBondContact O-N 2.76Å; I557-S561 PolarHBondContact O-OG 3.28Å
562R67.6Low54.3Low197 Ų19796.9 Ų96.974%0.74350%0.498SS*.THydrogen-bonded Turntrans-88.2-18.5169.9-79.6-179.5170.8-162.1-1.2114.3L558 Y560L558-R562 WeakPolarHBondContact O-CD 3.35Å; L558-R562 VanDerWaalsContact O-CG 3.26Å; L558-R562 WeakPolarHBondContact O-CG 3.49Å; Y560-R562 PolarHBondContact O-N 2.83Å
563K66.2Low55.3Low147 Ų14793.9 Ų93.964%0.63949%0.485SS*.THydrogen-bonded Turntrans-109.4-35.7-173.7-74.6172.7177.41740113.2N559 Y560N559-K563 WeakPolarHBondContact O-CD 3.41Å; N559-K563 VanDerWaalsContact O-CG 3.29Å; N559-K563 WeakPolarHBondContact O-CG 3.39Å; N559-K563 PolarHBondContact O-N 2.92Å; N559-K563 WeakPolarHBondContact OD1-CE 3.3Å; N559-K563 PolarHBondContact OD1-NZ 2.98Å; Y560-K563 PolarHBondContact O-N 3.18Å
564H60Low55.8Low77 Ų7791.8 Ų91.836%0.35647%0.471SS..SBendtrans-107.2136.3-179.4-57.6-99.6000108.5Y560 F585Y560-H564 HydrophobicContact CD1-CB 4.03Å; Y560-H564 AromaticContact CD1-CD2 3.68Å; Y560-H564 AromaticContact CD1-CG 3.91Å; Y560-H564 AromaticContact CD2-CD2 3.63Å; Y560-H564 AromaticContact CD2-NE2 3.75Å; Y560-H564 HydrophobicContact CE1-CB 3.79Å; Y560-H564 AromaticContact CE1-CD2 3.63Å; Y560-H564 AromaticContact CE1-CG 3.53Å; Y560-H564 AromaticContact CE2-CD2 3.58Å; Y560-H564 AromaticContact CE2-CE1 3.83Å; Y560-H564 AromaticContact CE2-NE2 3.42Å; Y560-H564 WeakPolarHBondContact CE2-NE2 3.3Å; Y560-H564 AromaticContact CG-CD2 3.68Å; Y560-H564 AromaticContact CZ-CD2 3.58Å; Y560-H564 AromaticContact CZ-CE1 3.74Å; Y560-H564 AromaticContact CZ-CG 3.66Å; Y560-H564 AromaticContact CZ-ND1 3.74Å; Y560-H564 AromaticContact CZ-NE2 3.7Å; Y560-H564 PolarHBondContact O-CD2 3.14Å; Y560-H564 PolarHBondContact O-N 2.93Å; H564-F585 HydrophobicContact CB-CD1 4.42Å; H564-F585 WeakPolarHBondContact O-CE1 3.35Å
565D62.3Low56.5Low145 Ų14595.5 Ų95.578%0.77549%0.485SS*.  trans-73148.1168.5-61.7-51.2000109
566A57.7Low56.9Low35 Ų3597.2 Ų97.229%0.28949%0.49SS..  trans-68.4137.3178.400000110.8M568 E583 I584 F585A566-M568 VanDerWaalsContact C-N 3.29Å; A566-E583 HydrophobicContact CB-CB 4.05Å; A566-E583 HydrophobicContact CB-CG 4.44Å; A566-I584 CarbonylContact C-O 3.52Å; A566-F585 HydrophobicContact CB-CD1 4.15Å; A566-F585 HydrophobicContact CB-CE1 3.76Å; A566-F585 HydrophobicContact CB-CZ 3.99Å
567L58.3Low57Low134 Ų134101.3 Ų101.370%0.70250%0.504SS*.SBendtrans-64.7-37.5170.2-79.1-178.4000111.1I584 G586L567-I584 PolarHBondContact N-O 3.18Å; L567-G586 VanDerWaalsContact CD1-CA 3.4Å
568M42.9Very low56.5Low63 Ų63103.2 Ų103.231%0.3151%0.505SS..EExtended strand (participates in β ladder)trans-148.2140.1177.4-164.3165.965.600110.1L422 A566 I584L422-M568 HydrophobicContact CD2-SD 4.11Å; A566-M568 VanDerWaalsContact C-N 3.29Å; M568-I584 HydrophobicContact CB-CB 4.46Å; M568-I584 HydrophobicContact CE-CD1 3.85Å; M568-I584 PolarHBondContact N-O 2.68Å; M568-I584 PolarHBondContact O-N 2.84Å
569A53.6Low56.3Low46 Ų46102.4 Ų102.438%0.3850%0.499SS..EExtended strand (participates in β ladder)trans-132.6116.717800000108.8L581 T582 E583A569-L581 HydrophobicContact CB-CD1 4.05Å; A569-T582 WeakPolarHBondContact CA-O 3.44Å; A569-E583 HydrophobicContact CB-CG 4.37Å
570Y50.7Low55.7Low108 Ų108102.1 Ų102.142%0.42449%0.494SS..EExtended strand (participates in β ladder)trans-119141.9-177.765-92.6000112.4Y572 L581 T582 I584Y570-Y572 HydrophobicContact CD2-CD1 4.02Å; Y570-Y572 HydrophobicContact CE2-CD1 4.01Å; Y570-Y572 HydrophobicContact CE2-CE1 4.14Å; Y570-L581 WeakPolarHBondContact O-CA 3.3Å; Y570-T582 HydrophobicContact CD1-CG2 4.46Å; Y570-T582 HydrophobicContact CE1-CG2 3.62Å; Y570-T582 HydrophobicContact CE2-CG2 4.43Å; Y570-T582 PolarHBondContact N-O 3.31Å; Y570-T582 PolarHBondContact O-N 3.05Å; Y570-T582 WeakPolarHBondContact OH-CG2 3.5Å; Y570-I584 HydrophobicContact CE1-CD1 4.03Å; Y570-I584 HydrophobicContact CE1-CG1 4.43Å
571Y67.8Low56Low123 Ų123102.5 Ų102.548%0.48250%0.5SS..EExtended strand (participates in β ladder)trans-114.4128.3-175.4-57.7-98.3000109.3M579 K580 L581Y571-M579 HydrophobicContact CD1-CG 4.44Å; Y571-M579 HydrophobicContact CD1-SD 3.89Å; Y571-K580 WeakPolarHBondContact CA-O 3.39Å; Y571-L581 HydrophobicContact CD1-CB 4.36Å; Y571-L581 HydrophobicContact CD1-CD1 4.16Å; Y571-L581 HydrophobicContact CE1-CB 4.4Å; Y571-L581 HydrophobicContact CE1-CD1 3.85Å; Y571-L581 HydrophobicContact CE1-CD2 4.39Å; Y571-L581 HydrophobicContact CE1-CG 4.44Å; Y571-L581 HydrophobicContact CE2-CD1 4.28Å
572Y58.3Low56.3Low112 Ų112102.5 Ų102.544%0.43950%0.498SS..EExtended strand (participates in β ladder)trans-137.1157.5177.863.9-81.5000110.2Y570 M579 K580Y570-Y572 HydrophobicContact CD2-CD1 4.02Å; Y570-Y572 HydrophobicContact CE2-CD1 4.01Å; Y570-Y572 HydrophobicContact CE2-CE1 4.14Å; Y572-M579 CarbonylContact O-C 3.5Å; Y572-M579 WeakPolarHBondContact O-CA 3.37Å; Y572-K580 HydrophobicContact CD1-CB 3.84Å; Y572-K580 HydrophobicContact CD2-CB 4Å; Y572-K580 HydrophobicContact CD2-CG 4.08Å; Y572-K580 HydrophobicContact CE1-CB 3.44Å; Y572-K580 VanDerWaalsContact CE1-CB 3.44Å; Y572-K580 HydrophobicContact CE1-CG 4.29Å; Y572-K580 HydrophobicContact CE2-CB 3.63Å; Y572-K580 HydrophobicContact CE2-CG 3.56Å; Y572-K580 HydrophobicContact CG-CB 4.1Å; Y572-K580 PolarHBondContact N-O 3.22Å; Y572-K580 PolarHBondContact O-N 2.95Å
573T55.2Low56Low87 Ų8797.7 Ų97.753%0.53448%0.484SS..EExtended strand (participates in β ladder)trans-95.4133.5169.6420000110R578T573-R578 WeakPolarHBondContact CA-O 3.39Å
574D64.1Low55.7Low36 Ų3694.3 Ų94.319%0.19347%0.472CS..  trans-73.9172.3166.369.613.3000112S576 N577 R578 K580D574-S576 PolarHBondContact O-N 2.68Å; D574-S576 VanDerWaalsContact OD1-CA 3.31Å; D574-S576 WeakPolarHBondContact OD1-CA 3.26Å; D574-S576 VanDerWaalsContact OD1-CB 3.26Å; D574-S576 WeakPolarHBondContact OD1-CB 3.33Å; D574-S576 PolarHBondContact OD1-N 2.96Å; D574-N577 WeakPolarHBondContact O-CA 3.26Å; D574-N577 PolarHBondContact O-N 3.39Å; D574-N577 PolarHBondContact OD1-N 2.85Å; D574-R578 PolarHBondContact N-O 2.77Å; D574-R578 VanDerWaalsContact OD1-CB 3.31Å; D574-R578 WeakPolarHBondContact OD1-CB 3.49Å; D574-R578 PolarHBondContact OD1-N 2.79Å; D574-K580 HydrophobicContact CB-CG 4.39Å; D574-K580 VanDerWaalsContact CG-CE 3.42Å; D574-K580 WeakPolarHBondContact OD2-CE 3.2Å; D574-K580 IonicContact OD2-NZ 3.7Å; D574-K580 PolarHBondContact OD2-NZ 3.35Å
575E55Low55.9Low206 Ų20692.8 Ų92.896%0.96347%0.465SS*.THydrogen-bonded Turntrans-54.9-19.8176.1-58.7176.8167.500113.5N577E575-N577 VanDerWaalsContact C-N 3.32Å
576S52.5Low55.2Low84 Ų8487.3 Ų87.359%0.58744%0.443SS*.THydrogen-bonded Turntrans-9114175.2-63.90000113.3D574 R578D574-S576 PolarHBondContact O-N 2.68Å; D574-S576 VanDerWaalsContact OD1-CA 3.31Å; D574-S576 WeakPolarHBondContact OD1-CA 3.26Å; D574-S576 VanDerWaalsContact OD1-CB 3.26Å; D574-S576 WeakPolarHBondContact OD1-CB 3.33Å; D574-S576 PolarHBondContact OD1-N 2.96Å; S576-R578 PolarHBondContact O-N 3.39Å
577N51.1Low54.9Low140 Ų14091.6 Ų91.675%0.74947%0.465SS*.SBendtrans55.623.7-172.6-83.9-47.3000114.2D574 E575D574-N577 WeakPolarHBondContact O-CA 3.26Å; D574-N577 PolarHBondContact O-N 3.39Å; D574-N577 PolarHBondContact OD1-N 2.85Å; E575-N577 VanDerWaalsContact C-N 3.32Å
578R39.2Very low54.3Low138 Ų13893.2 Ų93.252%0.52147%0.469SS..  trans-90.1126.2175.6-54.4176.2-179.4-121.5-1.9108.9T573 D574 S576 K580T573-R578 WeakPolarHBondContact CA-O 3.39Å; D574-R578 PolarHBondContact N-O 2.77Å; D574-R578 VanDerWaalsContact OD1-CB 3.31Å; D574-R578 WeakPolarHBondContact OD1-CB 3.49Å; D574-R578 PolarHBondContact OD1-N 2.79Å; S576-R578 PolarHBondContact O-N 3.39Å; R578-K580 PolarHBondContact O-N 3.27Å
579M49.5Very low54Low86 Ų8694.9 Ų94.942%0.42449%0.493SS..EExtended strand (participates in β ladder)trans-61.5139170-167.2179.8-7300110F531 Y571 Y572F531-M579 WeakPolarHBondContact CE1-O 3.41Å; F531-M579 HydrophobicContact CE2-CB 3.94Å; F531-M579 HydrophobicContact CE2-CG 3.91Å; F531-M579 HydrophobicContact CE2-SD 3.75Å; F531-M579 HydrophobicContact CZ-CB 3.76Å; F531-M579 HydrophobicContact CZ-CG 3.82Å; F531-M579 WeakPolarHBondContact CZ-O 3.15Å; F531-M579 HydrophobicContact CZ-SD 4.27Å; Y571-M579 HydrophobicContact CD1-CG 4.44Å; Y571-M579 HydrophobicContact CD1-SD 3.89Å; Y572-M579 CarbonylContact O-C 3.5Å; Y572-M579 WeakPolarHBondContact O-CA 3.37Å
580K48.6Very low53Low78 Ų78101 Ų10134%0.33951%0.514SS..EExtended strand (participates in β ladder)trans-121.4159.6173-58.2-74.8176.1163.80108Y571 Y572 D574 R578Y571-K580 WeakPolarHBondContact CA-O 3.39Å; Y572-K580 HydrophobicContact CD1-CB 3.84Å; Y572-K580 HydrophobicContact CD2-CB 4Å; Y572-K580 HydrophobicContact CD2-CG 4.08Å; Y572-K580 HydrophobicContact CE1-CB 3.44Å; Y572-K580 VanDerWaalsContact CE1-CB 3.44Å; Y572-K580 HydrophobicContact CE1-CG 4.29Å; Y572-K580 HydrophobicContact CE2-CB 3.63Å; Y572-K580 HydrophobicContact CE2-CG 3.56Å; Y572-K580 HydrophobicContact CG-CB 4.1Å; Y572-K580 PolarHBondContact N-O 3.22Å; Y572-K580 PolarHBondContact O-N 2.95Å; D574-K580 HydrophobicContact CB-CG 4.39Å; D574-K580 VanDerWaalsContact CG-CE 3.42Å; D574-K580 WeakPolarHBondContact OD2-CE 3.2Å; D574-K580 IonicContact OD2-NZ 3.7Å; D574-K580 PolarHBondContact OD2-NZ 3.35Å; R578-K580 PolarHBondContact O-N 3.27Å
581L59.2Low52.1Low70 Ų70101.8 Ų101.837%0.36653%0.532SS..EExtended strand (participates in β ladder)trans-132.2130.4174.3167.760.7000107.2A569 Y570 Y571 E583A569-L581 HydrophobicContact CB-CD1 4.05Å; Y570-L581 WeakPolarHBondContact O-CA 3.3Å; Y571-L581 HydrophobicContact CD1-CB 4.36Å; Y571-L581 HydrophobicContact CD1-CD1 4.16Å; Y571-L581 HydrophobicContact CE1-CB 4.4Å; Y571-L581 HydrophobicContact CE1-CD1 3.85Å; Y571-L581 HydrophobicContact CE1-CD2 4.39Å; Y571-L581 HydrophobicContact CE1-CG 4.44Å; Y571-L581 HydrophobicContact CE2-CD1 4.28Å; L581-E583 HydrophobicContact CD1-CG 4.03Å; L581-E583 HydrophobicContact CD2-CG 4.16Å; L581-E583 HydrophobicContact CG-CG 4Å
582T62.7Low50.6Low41 Ų41102.5 Ų102.525%0.25255%0.549SS..EExtended strand (participates in β ladder)trans-115.6131.3164.1-56.90000108.6A569 Y570A569-T582 WeakPolarHBondContact CA-O 3.44Å; Y570-T582 HydrophobicContact CD1-CG2 4.46Å; Y570-T582 HydrophobicContact CE1-CG2 3.62Å; Y570-T582 HydrophobicContact CE2-CG2 4.43Å; Y570-T582 PolarHBondContact N-O 3.31Å; Y570-T582 PolarHBondContact O-N 3.05Å; Y570-T582 WeakPolarHBondContact OH-CG2 3.5Å
583E61.2Low49.2Very low96 Ų96102.8 Ų102.845%0.44957%0.567SS.*EExtended strand (participates in β ladder)trans-112.7127176.5-64.2175.5148.500109A566 A569 L581 F585A566-E583 HydrophobicContact CB-CB 4.05Å; A566-E583 HydrophobicContact CB-CG 4.44Å; A569-E583 HydrophobicContact CB-CG 4.37Å; L581-E583 HydrophobicContact CD1-CG 4.03Å; L581-E583 HydrophobicContact CD2-CG 4.16Å; L581-E583 HydrophobicContact CG-CG 4Å; E583-F585 HydrophobicContact CB-CD2 4.4Å; E583-F585 HydrophobicContact CB-CE2 3.48Å; E583-F585 VanDerWaalsContact CB-CE2 3.48Å; E583-F585 HydrophobicContact CB-CZ 3.71Å; E583-F585 HydrophobicContact CG-CZ 4.49Å
584I60.1Low48.2Very low75 Ų75105.3 Ų105.339%0.38558%0.582SS.*EExtended strand (participates in β ladder)trans-105.3127.4175.4-63.6174.1000107.7A566 L567 M568 Y570A566-I584 CarbonylContact C-O 3.52Å; L567-I584 PolarHBondContact N-O 3.18Å; M568-I584 HydrophobicContact CB-CB 4.46Å; M568-I584 HydrophobicContact CE-CD1 3.85Å; M568-I584 PolarHBondContact N-O 2.68Å; M568-I584 PolarHBondContact O-N 2.84Å; Y570-I584 HydrophobicContact CE1-CD1 4.03Å; Y570-I584 HydrophobicContact CE1-CG1 4.43Å
585F63.4Low46.6Very low46 Ų46114.7 Ų114.720%0.20262%0.615CS.*  trans-113.3140.3179.8-60.6-91000110.4Y560 H564 A566 E583Y560-F585 HydrophobicContact CD1-CB 4.08Å; Y560-F585 HydrophobicContact CD1-CD1 4.47Å; Y560-F585 HydrophobicContact CD1-CG 4.34Å; Y560-F585 HydrophobicContact CE1-CB 3.93Å; H564-F585 HydrophobicContact CB-CD1 4.42Å; H564-F585 WeakPolarHBondContact O-CE1 3.35Å; A566-F585 HydrophobicContact CB-CD1 4.15Å; A566-F585 HydrophobicContact CB-CE1 3.76Å; A566-F585 HydrophobicContact CB-CZ 3.99Å; E583-F585 HydrophobicContact CB-CD2 4.4Å; E583-F585 HydrophobicContact CB-CE2 3.48Å; E583-F585 VanDerWaalsContact CB-CE2 3.48Å; E583-F585 HydrophobicContact CB-CZ 3.71Å; E583-F585 HydrophobicContact CG-CZ 4.49Å
586G48.9Very low45.2Very low30 Ų30110.1 Ų110.131%0.30961%0.606SS.*  trans-75.5127.3171.600000110.4Y560 L567Y560-G586 PolarHBondContact OH-O 3.38Å; L567-G586 VanDerWaalsContact CD1-CA 3.4Å
587V51.4Low44.3Very low125 Ų125111.9 Ų111.976%0.75862%0.618SS**  trans-95.6103.4175.6-176.70000108.7
588E45.5Very low43.1Very low167 Ų167110.6 Ų110.678%0.7862%0.62SS**  trans-73.9128.3165-68.1-176.1168.500108.7E590E588-E590 PolarHBondContact O-N 3.39Å
589A36.3Very low42.9Very low98 Ų98109.7 Ų109.781%0.8163%0.632SS**  trans-79.2115.6176.300000110
590E31.4Very low41.9Very low176 Ų176111.4 Ų111.482%0.82265%0.647SS**  trans-64.4139.9174.8-77.6-158.4172.700111.6E588 T592E588-E590 PolarHBondContact O-N 3.39Å; E590-T592 PolarHBondContact O-N 3.1Å
591P33.6Very low40.9Very low124 Ų124117.5 Ų117.581%0.80567%0.669SS**  trans-7394.717829.9-34.4000110.9S593P591-S593 PolarHBondContact O-N 3.3Å; P591-S593 VanDerWaalsContact O-N 3.1Å
592T35.2Very low39.4Very low137 Ų137126 Ų12684%0.8470%0.697SS**  trans-59.5112.2178.647.70000111.9E590E590-T592 PolarHBondContact O-N 3.1Å
593S29.7Very low37.8Very low118 Ų118130.5 Ų130.583%0.82572%0.719SS**  trans-106.2111.3172.358.50000110.7P591P591-S593 PolarHBondContact O-N 3.3Å; P591-S593 VanDerWaalsContact O-N 3.1Å
594V34.4Very low36.5Very low140 Ų140130.8 Ų130.885%0.84872%0.724SS**  trans-131.1145176.8-176.10000109.4
595R29.8Very low35.2Very low234 Ų234134.9 Ų134.988%0.88374%0.741SS**  trans-92.5133.6-166.4-70.4175.5169.5167-5113.7
596S26Very low33.7Very low109 Ų109139.2 Ų139.276%0.76277%0.771SS**  trans34.2115.6141.4650000120.9
597S33.4Very low32.8Very low121 Ų121141.1 Ų141.185%0.84679%0.791SS**  -156116.8129.358.20000111.8
598S26.2Very low31.6Very low113 Ų113141.5 Ų141.579%0.7980%0.798SS**  trans-75.7179.1167.2-42.20000110.5
599P34.2Very low30.9Very low119 Ų119139.4 Ų139.477%0.77380%0.799SS**  cis-127.6-162.29.727.7-0.2000112
600V29.8Very low30.7Very low122 Ų122142 Ų14274%0.73980%0.798SS**  cis-154.3149.331.8174.90000112.5
601Y26Very low30.6Very low206 Ų206141 Ų14181%0.80879%0.793SS**  trans-19138162.1-82.2-105.7000120
602R28.6Very low30.3Very low250 Ų250142 Ų14294%0.94379%0.792SS**  -154.2165.397.7-109.8178.3-179.1177.61112.1
603N29.3Very low30.1Very low134 Ų134142.7 Ų142.772%0.71779%0.791SS**  trans-143.2167.1-163.3-16819.5000111.7
604N33Very low30.1Very low103 Ų103144.6 Ų144.655%0.55179%0.791SS**  trans109.7119.5159.2-61.7-1.4000118.5
605Q32.9Very low29.9Very low161 Ų161144.9 Ų144.975%0.75279%0.792SS**  68.5144.6125.3-61.4167.2-300118.8
606T32.7Very low30Very low136 Ų136140.7 Ų140.783%0.83479%0.788SS**  cis-163.1144-29.10000111.8
607G29.3Very low30.3Very low70 Ų70140.9 Ų140.972%0.72279%0.789SS**  trans61.2116.3138.300000122.4
608C26.1Very low29.8Very low134 Ų134138.6 Ų138.691%0.90579%0.785SS**  176.6131.2113.9-98.10000111.9
609P30.5Very low29.8Very low123 Ų123141.3 Ų141.380%0.79979%0.789SS**  trans-107.3158.8173.839-31.8000113.2
610L32.9Very low29.2Very low151 Ų151140.8 Ų140.879%0.79179%0.787SS**  trans-156.2132.1161.7-108.3163.8000111.4
611E30.1Very low29.1Very low155 Ų155143 Ų14372%0.72479%0.794SS**  trans17.9116.7157.2-70.4172.7132.500119.8
612N26Very low28.9Very low146 Ų146137.1 Ų137.178%0.78179%0.788SS**  74.1112.576-76.4-19.9000113.8
613D31.9Very low28.7Very low152 Ų152129.8 Ų129.881%0.81378%0.78SS**  trans-155.6148.1130.2-128.3-22.2000114
614L29.7Very low28.5Very low158 Ų158132.8 Ų132.883%0.82779%0.79SS**  trans39.7107.9163.1-67.4161.3000121
615V29.7Very low28Very low145 Ų145134.3 Ų134.388%0.87981%0.807SS**PPolyproline II helixtrans-85.2132162174.40000109.9
616D32.7Very low27.7Very low147 Ų147130 Ų13079%0.78681%0.806SS**PPolyproline II helixtrans-91.6156.5170.2-152.5-17000112.5
617S31.6Very low27.3Very low112 Ų112133.2 Ų133.278%0.78381%0.809SS**PPolyproline II helixtrans-64.4147.7-168.555.60000115.6
618G23.5Very low27.2Very low74 Ų74134.4 Ų134.476%0.76381%0.812SS**  trans-129.4154.9175.900000112.8
619I25.9Very low27.1Very low170 Ų170137 Ų13787%0.87281%0.81SS**  trans-128.2129.2163.7-63.1-179.4000107.6
620S21.3Very low27Very low107 Ų107136.6 Ų136.675%0.74881%0.808SS**  trans-123.5131.1178.41760000110.1
621I26.6Very low26.7Very low169 Ų169134.4 Ų134.487%0.86781%0.811SS**  trans-135.2133.7160.8-59-177.8000106.2
622A23.3Very low26.5Very low83 Ų83131 Ų13169%0.68682%0.817SS**  trans-120.2171.3-165.300000113.2
623A23.5Very low26.7Very low95 Ų95128.3 Ų128.379%0.78581%0.811SS**  trans71.5150.617600000115.3
624E24.9Very low26.6Very low197 Ų197128.8 Ų128.892%0.92181%0.812SS**  cis-116.1165.19.5-68.8-176.3112.600114.5
625C23.6Very low26.7Very low136 Ų136131.3 Ų131.392%0.91981%0.811SS**  trans-100133.7-179.4172.80000111.6
626G25.5Very low26.9Very low71 Ų71134.2 Ų134.273%0.73281%0.806SS**  trans-147.834.2-159.100000119.8
627K25.9Very low26.9Very low202 Ų202135.7 Ų135.788%0.87881%0.805SS**  trans72.4133.1169.9-55.2170.7-179171.10117.2
628A25.7Very low27.1Very low96 Ų96137 Ų13779%0.79380%0.802SS**PPolyproline II helixtrans-75148.5170.400000112.2
629H25.6Very low27.6Very low187 Ų187140 Ų14087%0.86680%0.797SS**PPolyproline II helixtrans-98.6122.4164.5-95.5-91.3000109.7
630P27.8Very low28.1Very low116 Ų116140 Ų14075%0.75379%0.791SS**PPolyproline II helixtrans-74.7148.4170.631.4-33.7000110.9
631A26.8Very low28.9Very low104 Ų104140.6 Ų140.686%0.8678%0.784SS**SBendtrans-66162.3170.500000112
632G25.9Very low29.3Very low83 Ų83142.6 Ų142.686%0.85678%0.781SS**  trans89.964.9167.200000116.9
633S28.5Very low29.9Very low91 Ų91146.1 Ų146.164%0.63678%0.783SS**  trans-146.227.2168.4-170.30000116.3
634L31.3Very low30.6Very low161 Ų161150.4 Ų150.484%0.84378%0.784SS**SBendtrans-80.9-21.7176.7-129.7145.8000113.3
635R32.1Very low31.2Very low211 Ų211147.6 Ų147.680%0.79678%0.775SS**SBendtrans-89-9.6-175.2-142171.1-169.4156.25.8116.2
636R32.5Very low31.7Very low207 Ų207149.6 Ų149.678%0.78177%0.771SS**SBendtrans-103.40.3-173.3-80.9-175173.5171.50.1116.4
637K33.9Very low32.1Very low178 Ų178150.3 Ų150.377%0.77477%0.77SS**SBendtrans-90.7-16.5179.6-106.6-179.2177.51790115.1
638L35.3Very low32.3Very low138 Ų138151 Ų15172%0.72377%0.773SS**SBendtrans-90-25.9-176.9-86.6161.3000114.6
639E33.2Very low32.5Very low139 Ų139153.8 Ų153.865%0.6578%0.775SS**Hα-helixtrans-72.8-36.1-179.1-68.7179.2130.100112.7I641 R642E639-I641 PolarHBondContact O-N 3.34Å; E639-I641 VanDerWaalsContact O-N 3.07Å; E639-R642 WeakPolarHBondContact O-CB 3.39Å; E639-R642 PolarHBondContact O-N 2.91Å
640K36.9Very low32.7Very low170 Ų170150.6 Ų150.674%0.73977%0.773SS**Hα-helixtrans-68.9-3.6178.3-80.2-166.2170.6-173.10115.7
641I38.3Very low32.9Very low119 Ų119148.1 Ų148.161%0.6177%0.769SS**Hα-helixtrans-92.2-21.3169.3-63.8178.5000110.8E639E639-I641 PolarHBondContact O-N 3.34Å; E639-I641 VanDerWaalsContact O-N 3.07Å
642R34.4Very low33.1Very low211 Ų211150.7 Ų150.780%0.79677%0.766SS**Hα-helixtrans-80.7-24.7-176.3-155.6169.7-172164.12.3113.7E639 K644E639-R642 WeakPolarHBondContact O-CB 3.39Å; E639-R642 PolarHBondContact O-N 2.91Å; R642-K644 PolarHBondContact O-N 3.49Å
643E35.9Very low33.3Very low156 Ų156155.5 Ų155.573%0.72976%0.764SS**THydrogen-bonded Turntrans-78.6-11.3-178.7-63.9-178.2130.900114.4
644K38.7Very low33.5Very low186 Ų186159.6 Ų159.681%0.80978%0.778SS**THydrogen-bonded Turntrans-90.6-5.6-177.6-96.7-171.4172.1-1730116R642R642-K644 PolarHBondContact O-N 3.49Å
645N37.7Very low33.5Very low137 Ų137155.2 Ų155.273%0.73377%0.772SS**SBendtrans-103.320-175.1-70-4.6000114.3
646H34.1Very low33.2Very low179 Ų179153.4 Ų153.483%0.82978%0.777SS**SBendtrans-122.917.7-178.1-91.3-68.4000114.9
647A34Very low33.1Very low86 Ų86148.7 Ų148.771%0.71178%0.775SS**  trans-133.554-177.700000112.7
648F29.4Very low32.9Very low217 Ų217144.7 Ų144.795%0.95277%0.77SS**  trans-151.160173.7-125.4-77.7000112.9
649D29.4Very low32.5Very low154 Ų154143.6 Ų143.682%0.82477%0.774SS**  trans-145.3157.7166-161-2000110.3
650S31.5Very low32.3Very low120 Ų120143.2 Ų143.284%0.83979%0.787SS**  trans70.2141.4-172.378.50000117.1
651G30.4Very low31.8Very low64 Ų64139.7 Ų139.766%0.6679%0.789SS**  trans107.164.7174.800000115.8
652I32.2Very low31.5Very low157 Ų157142.1 Ų142.181%0.80580%0.802SS**  60.595.293.3-59.8173.4000112.1
653K30.1Very low31Very low184 Ų184137.1 Ų137.180%0.880%0.799SS**  89.2143.578.6-105.9-178.8177.6177.10114.5
654L33.1Very low30.9Very low177 Ų177138.8 Ų138.893%0.92780%0.804SS**  trans74144.9174.5-54.2155.4000114.5
655G30.7Very low30.6Very low70 Ų70135 Ų13572%0.72280%0.8SS**  cis-162.1173.5-2.700000111.9
656L26Very low30Very low173 Ų173139.2 Ų139.291%0.90681%0.808SS**  trans-89.8149.1-177-57.289.3000112.3
657S29.2Very low30.1Very low107 Ų107136.4 Ų136.475%0.74881%0.805SS**  155150.9112.171.30000116
658S29.5Very low29.9Very low94 Ų94138.7 Ų138.766%0.65781%0.811SS**  trans59111146.661.50000122.6
659S27.3Very low29.9Very low116 Ų116134.7 Ų134.781%0.81181%0.808SS**  61.3114.2118-49.30000122.1
660S30Very low30Very low131 Ų131137.4 Ų137.492%0.91681%0.807SS**  168.2167115.951.20000111.5
661A26.2Very low30.2Very low96 Ų96140.9 Ų140.979%0.79381%0.807SS**  trans-116.2145.2-17000000113.5
662I30.7Very low30.3Very low170 Ų170140.8 Ų140.887%0.87281%0.806SS**  trans-132.8141.1165.5-62.9-176.9000108.9
663S25.5Very low30.4Very low106 Ų106141.1 Ų141.174%0.74181%0.81SS**  trans-122.1147.2-174.2168.60000111.9
664K33.1Very low30.7Very low191 Ų191139.5 Ų139.583%0.8382%0.815SS**  trans177.8149.2159.8-95.4145.2-173.6-179.50108.9
665S31.6Very low30.5Very low105 Ų105135.1 Ų135.173%0.73480%0.804SS**  cis-173.8134-23.745.20000108.9
666Y26.1Very low30.5Very low226 Ų226143.4 Ų143.489%0.88681%0.814SS**  trans-99.9149.7172.6-82.7-89.9000112
667P36.9Very low30.8Very low120 Ų120143.9 Ų143.978%0.77981%0.811SS**  trans-90.7140.8159.134.7-29.7000111.6
668T30.1Very low30.8Very low134 Ų134146.5 Ų146.582%0.82281%0.812SS**  trans-128154.5174.559.40000110.4
669C29.1Very low30.7Very low133 Ų133149.5 Ų149.590%0.89982%0.815SS**  trans-128.4151.8159.5-148.80000112.6
670R31.5Very low30.9Very low212 Ų212151.8 Ų151.880%0.881%0.813SS**  trans-110.4172.5-176.4-89.4168.8162.3176.1-5.4108.3
671K35.3Very low30.9Very low192 Ų192154.7 Ų154.784%0.83581%0.812SS**  cis-159.117312.4-120.1156.4177.9-173.20105.2
672G33.3Very low31Very low63 Ų63153.8 Ų153.865%0.64981%0.812SS**  cis-176.1-162.86.800000111.7
673N32.7Very low30.8Very low163 Ų163153.8 Ų153.887%0.87281%0.808SS**  trans-74.7172.6-167.1-50.8-16.4000113.4
674V36.1Very low30.9Very low151 Ų151157 Ų15792%0.91581%0.809SS**  -150.9175.251.6174.30000111.7
675A30.6Very low30.7Very low84 Ų84154.1 Ų154.169%0.69481%0.808SS**  trans-119.1174.5-160.100000116.9
676R29.3Very low30.5Very low245 Ų245154.5 Ų154.593%0.92581%0.809SS**  trans72.3143.4178.2-61.4176.6171.7176.7-3.8113.6
677Q33.1Very low30.8Very low182 Ų182149.1 Ų149.185%0.8580%0.804SS**  cis-141.8-149.730.3-148.6162.3-4.900113.3
678Q28.9Very low30.4Very low163 Ų163148.3 Ų148.376%0.76280%0.802SS**  trans-105.6163.2-164.1-68.7165.1-76.700115.1
679Q28.4Very low30.3Very low157 Ų157154.1 Ų154.173%0.73481%0.808SS**  trans87138.9144.5-93.8-175.913.200122.3
680Q30.3Very low30.2Very low163 Ų163152 Ų15276%0.76280%0.801SS**  trans80.6155.8152-67.718042.700121.1
681H29.7Very low30.2Very low192 Ų192149.7 Ų149.789%0.88980%0.802SS**  trans-56.7154.2-162-55.7-63.4000117.3
682G28.5Very low30Very low78 Ų78145.4 Ų145.480%0.80479%0.794SS**  trans178.398.1167.300000113.3
683Q27.6Very low29.7Very low170 Ų170149.5 Ų149.579%0.79480%0.802SS**  trans-73.5157.3-178.5-127.2-175.823.600113.2
684K27.7Very low29.5Very low174 Ų174150.1 Ų150.176%0.75780%0.804SS**  trans69.9152.1165.4-56.8165.7-175.1178.60114.4
685T28.5Very low28.9Very low130 Ų130150.8 Ų150.880%0.79880%0.801SS**  cis-161.7179.7-13.221.30000106.1
686C27.3Very low28.7Very low112 Ų112157.9 Ų157.976%0.75781%0.81SS**  cis-157.7-165.513.7-1490000111.2
687S31.9Very low28.7Very low114 Ų114151.4 Ų151.480%0.79780%0.802SS**  trans75.9149.6165.576.90000118.5
688S28.2Very low28.4Very low103 Ų103149.6 Ų149.672%0.7280%0.804SS**  cis150.9115.9-30.1174.10000108.2
689W27.9Very low28.4Very low255 Ų255146.8 Ų146.897%0.96680%0.802SS**  trans-146.2134.3155.7-88.290.2000108
690A27.4Very low28.3Very low89 Ų89148.2 Ų148.274%0.73681%0.809SS**  trans-143.5146-178.300000110.5
691I31.1Very low28.2Very low163 Ų163146 Ų14684%0.83681%0.811SS**  trans-135.7138.9170.3-63.6-176.5000107.5
692P30.7Very low28.1Very low103 Ų103144.3 Ų144.367%0.66981%0.809SS**  trans-117.5170.4-154.142.4-32.8000116.2
693N27.4Very low28Very low149 Ų149146.4 Ų146.480%0.79781%0.808SS**  trans51.8114.8148-65.1-13.9000120.5
694L28.5Very low28.1Very low175 Ų175143.4 Ų143.492%0.91680%0.798SS**  trans-148.497.3137-117.9169.6000110.9
695L24.7Very low27.9Very low166 Ų166144.3 Ų144.387%0.86981%0.807SS**  trans-104.6132.8169.5-88.9166.9000109.1
696R26.6Very low27.8Very low233 Ų233144.4 Ų144.488%0.87980%0.802SS**  trans-154.7143.7157.1-142.6174.7-168.5-160.80.3114.4
697S29.1Very low27.7Very low108 Ų108148.9 Ų148.976%0.75581%0.809SS**  trans55.396.5160.249.70000118.3
698T25.3Very low27.4Very low144 Ų144149.4 Ų149.488%0.88380%0.802SS**  trans-85.5138.9151.246.90000111.4
699S30.4Very low27.3Very low104 Ų104149.4 Ų149.473%0.72780%0.799SS**  trans-163.9100.3156.654.20000106.4
700E26.6Very low27.4Very low187 Ų187146.1 Ų146.187%0.87480%0.795SS**  81.8150.382.2-78.5-162.4138.400114.2
701S27.1Very low27.6Very low117 Ų117153.7 Ų153.782%0.81880%0.804SS**  trans58.3103.4-177.359.50000118.2
702D27.6Very low27.6Very low157 Ų157149.2 Ų149.284%0.8479%0.787SS**  trans-156.297.8137-149.91.5000110.2D704D702-D704 PolarHBondContact O-N 2.89Å
703P27.2Very low27.5Very low121 Ų121155 Ų15579%0.78680%0.796SS**  trans-100.679.3-167.237.5-33.8000113.7
704D29.1Very low28.1Very low108 Ų108149.4 Ų149.458%0.57877%0.771SS**  trans-129.557178.9-140.511.1000113.6D702 L706D702-D704 PolarHBondContact O-N 2.89Å; D704-L706 VanDerWaalsContact C-N 3.28Å; D704-L706 PolarHBondContact O-N 3.31Å; D704-L706 WeakPolarHBondContact OD1-CD1 3.42Å
705M24.6Very low28.4Very low193 Ų193148.4 Ų148.495%0.95177%0.766SS**  trans-74.874.7168.8-97-101.8-81.800110.7
706L26.4Very low28.9Very low132 Ų132143.1 Ų143.169%0.69174%0.743SS**  trans-104.1136.7178.4-78.4174.9000113.5D704D704-L706 VanDerWaalsContact C-N 3.28Å; D704-L706 PolarHBondContact O-N 3.31Å; D704-L706 WeakPolarHBondContact OD1-CD1 3.42Å
707F23.5Very low29.4Very low206 Ų206138.8 Ų138.890%0.90474%0.735SS**PPolyproline II helixtrans-67.7133.3-172.9-85.1-117.1000112.7
708I27.3Very low29.2Very low125 Ų125138.8 Ų138.864%0.64174%0.735SS**PPolyproline II helixtrans-93.9133.9163.4-57.9175.5000107.6S712I708-S712 VanDerWaalsContact CG2-OG 3.29Å; I708-S712 WeakPolarHBondContact CG2-OG 3.37Å
709P25Very low29.4Very low102 Ų102139.3 Ų139.366%0.66273%0.728SS**PPolyproline II helixtrans-57.5138.1175-24.634.4000112.2R711P709-R711 PolarHBondContact O-N 3.16Å
710E29.3Very low29.1Very low187 Ų187141.6 Ų141.687%0.87473%0.732SS**G310 helixtrans-64.6-7.9-165.1-63.3-178.3118.900115.7S712E710-S712 VanDerWaalsContact C-N 3.29Å; E710-S712 PolarHBondContact O-N 3.35Å
711R31.8Very low29.2Very low247 Ų247138 Ų13893%0.93272%0.722SS**G310 helixtrans-71.7-9.7-179.2-75.3-174.6170.6-177.6-2.5115.5P709P709-R711 PolarHBondContact O-N 3.16Å
712S31.8Very low29.1Very low70 Ų70137 Ų13749%0.4972%0.715SS.*G310 helixtrans-109.4-7.9-175.963.30000115.7I708 E710 A714I708-S712 VanDerWaalsContact CG2-OG 3.29Å; I708-S712 WeakPolarHBondContact CG2-OG 3.37Å; E710-S712 VanDerWaalsContact C-N 3.29Å; E710-S712 PolarHBondContact O-N 3.35Å; S712-A714 PolarHBondContact O-N 3.22Å; S712-A714 VanDerWaalsContact O-N 3.12Å
713R29.3Very low29Very low223 Ų223140.2 Ų140.284%0.84272%0.717SS**  trans-77.297172.1-91.7-175.6170.9157.7-1.7110.5
714A38.7Very low29Very low33 Ų33143.2 Ų143.227%0.27372%0.721SS.*  trans-62.9141.7155.900000109.4S712 C716S712-A714 PolarHBondContact O-N 3.22Å; S712-A714 VanDerWaalsContact O-N 3.12Å; A714-C716 PolarHBondContact O-N 2.85Å
715N35.3Very low29Very low154 Ų154141.1 Ų141.182%0.82472%0.724SS**  trans-72.367172.8-75.6-13.7000110.9I717N715-I717 PolarHBondContact O-N 3.32Å
716C35.2Very low29.2Very low55 Ų55135.6 Ų135.637%0.37272%0.717SS.*  trans-61.9105.2157.1-65.50000106.5C52 A714 S718C52-C716 HydrophobicContact CB-CB 4.15Å; C52-C716 WeakPolarHBondContact CB-SG 3.19Å; C52-C716 WeakPolarHBondContact SG-CB 3.33Å; C52-C716 CovalentContact SG-SG 2.04Å; C52-C716 PolarHBondContact SG-SG 3.06Å; A714-C716 PolarHBondContact O-N 2.85Å; C716-S718 PolarHBondContact O-N 3.43Å
717I36.2Very low29.3Very low142 Ų142133.9 Ų133.973%0.72872%0.716SS**  trans-57.2136.4-162.7-64.2176000111.4N715 E719N715-I717 PolarHBondContact O-N 3.32Å; I717-E719 HydrophobicContact CG2-CG 4.1Å; I717-E719 PolarHBondContact O-N 2.99Å
718S26.6Very low29.9Very low107 Ų107129.6 Ų129.675%0.74871%0.712SS**  trans-74.768.717257.10000111C716 N720C716-S718 PolarHBondContact O-N 3.43Å; S718-N720 PolarHBondContact O-N 3.26Å
719E27.7Very low30.3Very low156 Ų156130.4 Ų130.473%0.72972%0.717SS**  trans-70.782.2161.3-71.1-162.2158.800108.9I717 V721I717-E719 HydrophobicContact CG2-CG 4.1Å; I717-E719 PolarHBondContact O-N 2.99Å; E719-V721 HydrophobicContact CB-CG2 4.11Å; E719-V721 PolarHBondContact O-N 3.37Å
720N25.3Very low30.6Very low152 Ų152133.6 Ų133.681%0.81373%0.729SS**  trans-61.681.3146.5-78.1-14000106.7S718 S722S718-N720 PolarHBondContact O-N 3.26Å; N720-S722 PolarHBondContact O-N 2.85Å
721V27.5Very low31Very low110 Ų110130 Ų13067%0.66772%0.724SS**  trans-65.794.3162.5-178.20000105.8E719 Y723E719-V721 HydrophobicContact CB-CG2 4.11Å; E719-V721 PolarHBondContact O-N 3.37Å; V721-Y723 PolarHBondContact O-N 2.84Å
722S25.5Very low31.1Very low96 Ų96123.8 Ų123.867%0.67172%0.718SS**  trans-57.3106170.140.80000107.9N720 E724N720-S722 PolarHBondContact O-N 2.85Å; S722-E724 PolarHBondContact O-N 2.83Å
723Y25.2Very low31.3Very low225 Ų225133.4 Ų133.488%0.88276%0.756SS**  trans-60.3105.9160.7-118.3-92.5000106.4V721 G725V721-Y723 PolarHBondContact O-N 2.84Å; Y723-G725 PolarHBondContact O-N 2.84Å
724E28.5Very low31.4Very low185 Ų185129 Ų12986%0.86475%0.752SS**  trans-70.474.2166.4-71.3-160.5153.200109S722 G726S722-E724 PolarHBondContact O-N 2.83Å; E724-G726 PolarHBondContact O-N 3.31Å; E724-G726 VanDerWaalsContact O-N 3.1Å
725G28.3Very low31Very low63 Ų63134 Ų13465%0.64978%0.777SS**  trans-64.7102.3155.300000107Y723 S727Y723-G725 PolarHBondContact O-N 2.84Å; G725-S727 PolarHBondContact O-N 3.26Å
726G28.4Very low30.8Very low77 Ų77132.9 Ų132.979%0.79477%0.774SS**  trans-60.697-174.400000112.5E724 S728E724-G726 PolarHBondContact O-N 3.31Å; E724-G726 VanDerWaalsContact O-N 3.1Å; G726-S728 PolarHBondContact O-N 3.15Å
727S29.7Very low30.5Very low97 Ų97137.5 Ų137.568%0.67880%0.798SS**  trans-74.498.4165.6-173.20000108.4G725G725-S727 PolarHBondContact O-N 3.26Å
728S35.8Very low30.2Very low116 Ų116137.2 Ų137.281%0.81180%0.802SS**  trans-85.3114.9160.857.60000108.1G726G726-S728 PolarHBondContact O-N 3.15Å
729D35.3Very low30.4Very low141 Ų141139.2 Ų139.275%0.75481%0.806SS**  trans-66.1159.5-166.9-65.2-57.9000115.4
730N31.7Very low30.6Very low170 Ų170138 Ų13891%0.90981%0.811SS**  trans-74.9126.1168.3-64.3-66.2000110.7
731S37.8Very low31Very low112 Ų112136.9 Ų136.978%0.78381%0.811SS**  trans-154.5117.3148.361.50000111.4
732S33.5Very low31.3Very low115 Ų115139.2 Ų139.280%0.80482%0.823SS**  trans-43.3127.7165.4480000114.7
733E36.1Very low31.8Very low273 Ų273143.1 Ų143.1100%1.27684%0.837SS**  -154096.8-94.7-173.2137.900110.3

Retrieved 733 of 733 residues in 239.6 ms (Link to these results)