A0A077ZB14_TRITR Loading...

Calreticulin

AlphaFold DB , UniProt , Accession A0A077ZB14, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 411 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M44.8Very low38.4Very low227 Ų227138.7 Ų138.7100%1.11878%0.775SS**  095.80-95.7170.460.100108.2L3M1-L3 PolarHBondContact O-N 3.29Å
2I38.2Very low39.1Very low167 Ų167140.5 Ų140.586%0.85678%0.78SS**  trans-86.1106.7174.5-64170.9000106L4I2-L4 PolarHBondContact O-N 3.22Å
3L39.4Very low40.5Very low144 Ų144136.5 Ų136.575%0.75478%0.777SS**  trans-76.7103.6179-152.586.3000107.9M1 L5M1-L3 PolarHBondContact O-N 3.29Å; L3-L5 PolarHBondContact O-N 3.2Å; L3-L5 VanDerWaalsContact O-N 3.17Å
4L39.7Very low42.5Very low146 Ų146133.7 Ų133.776%0.76477%0.77SS**  trans-72.1104.1175.2-145.295.2000108.3I2 V6I2-L4 PolarHBondContact O-N 3.22Å; L4-V6 PolarHBondContact O-N 2.92Å; L4-V6 VanDerWaalsContact O-N 3.1Å
5L39.1Very low45Very low144 Ų144129.4 Ų129.475%0.75475%0.748SS**  trans-69101.2168.3-106.3118.5000108.4L3 L7L3-L5 PolarHBondContact O-N 3.2Å; L3-L5 VanDerWaalsContact O-N 3.17Å; L5-L7 PolarHBondContact O-N 3.26Å; L5-L7 VanDerWaalsContact O-N 3.1Å
6V39.2Very low47.9Very low111 Ų111124.2 Ų124.267%0.67372%0.719SS**  trans-74.895.2166.7-179.80000107.4L4 I8L4-V6 PolarHBondContact O-N 2.92Å; L4-V6 VanDerWaalsContact O-N 3.1Å; V6-I8 HydrophobicContact CG1-CG1 3.93Å; V6-I8 PolarHBondContact O-N 3.26Å
7L34.9Very low50.7Low139 Ų139120 Ų12073%0.72870%0.696SS**  trans-66.795.5163.9-102.5133.7000107.9L5 T9L5-L7 PolarHBondContact O-N 3.26Å; L5-L7 VanDerWaalsContact O-N 3.1Å; L7-T9 PolarHBondContact O-N 3.14Å
8I37.6Very low53.3Low147 Ų147113.6 Ų113.675%0.75466%0.658SS**  trans-73.587165.1-57.2176.4000106.2V6 S10V6-I8 HydrophobicContact CG1-CG1 3.93Å; V6-I8 PolarHBondContact O-N 3.26Å; I8-S10 PolarHBondContact O-N 3.46Å
9T33Very low55.6Low114 Ų114107.6 Ų107.670%0.69962%0.623SS**  trans-69.397.7163.950.30000107L7 A11L7-T9 PolarHBondContact O-N 3.14Å; T9-A11 VanDerWaalsContact C-N 3.31Å; T9-A11 PolarHBondContact O-N 3.01Å
10S38.7Very low57.6Low94 Ų94104.8 Ų104.866%0.65761%0.606SS**  trans-61.398.6164.750.90000107.4I8 L12I8-S10 PolarHBondContact O-N 3.46Å; S10-L12 VanDerWaalsContact C-N 3.29Å; S10-L12 PolarHBondContact O-N 2.69Å
11A37.8Very low59.4Low93 Ų93100 Ų10077%0.76958%0.578SS**  trans-61.396.2169.900000107.4T9 A13T9-A11 VanDerWaalsContact C-N 3.31Å; T9-A11 PolarHBondContact O-N 3.01Å; A11-A13 PolarHBondContact O-N 2.97Å
12L46.7Very low61.8Low160 Ų16092.7 Ų92.784%0.83854%0.538SS*.  trans-66.891.4165.3-82.7145.9000105.7S10 S14S10-L12 VanDerWaalsContact C-N 3.29Å; S10-L12 PolarHBondContact O-N 2.69Å; L12-S14 PolarHBondContact O-N 3.38Å
13A57.9Low64.5Low89 Ų8984.8 Ų84.874%0.73650%0.497SS*.PPolyproline II helixtrans-52.7131174.200000108.4A11A11-A13 PolarHBondContact O-N 2.97Å
14S67.4Low67.1Low97 Ų9782.8 Ų82.868%0.67849%0.488SS*.PPolyproline II helixtrans-58.2144.7176.4-57.80000110.1L12 T16L12-S14 PolarHBondContact O-N 3.38Å; S14-T16 PolarHBondContact O-N 3.21Å
15P80.1Confident69.6Low69 Ų6978.9 Ų78.945%0.44847%0.467SS..PPolyproline II helixtrans-55131.8-179.126.4-37.6000110.7D321P15-D321 HydrophobicContact CB-CB 3.26Å; P15-D321 VanDerWaalsContact CB-OD2 3.3Å; P15-D321 WeakPolarHBondContact CB-OD2 3.32Å; P15-D321 HydrophobicContact CG-CB 4.48Å
16T92.5Very high72.2Confident46 Ų4674.1 Ų74.128%0.28245%0.454SS..PPolyproline II helixtrans-101122.7178.8-520000109.2S14 Y18 T319 D320S14-T16 PolarHBondContact O-N 3.21Å; T16-Y18 HydrophobicContact CG2-CD1 3.87Å; T16-Y18 HydrophobicContact CG2-CE1 3.47Å; T16-Y18 VanDerWaalsContact CG2-CE1 3.47Å; T16-T319 VanDerWaalsContact O-CA 3.28Å; T16-T319 WeakPolarHBondContact O-CA 3.31Å; T16-T319 WeakPolarHBondContact O-CB 3.49Å; T16-T319 PolarHBondContact O-OG1 3.03Å; T16-D320 PolarHBondContact N-OD1 3.48Å; T16-D320 PolarHBondContact O-N 3.36Å
17V94.8Very high74.9Confident53 Ų5373.7 Ų73.732%0.32145%0.448SS..EExtended strand (participates in β ladder)trans-93.1118.2169.2178.30000107.4D20 L317V17-D20 HydrophobicContact CG1-CB 3.87Å; V17-L317 HydrophobicContact CG1-CD1 4.04Å
18Y96.8Very high77.8Confident4 Ų469.3 Ų69.32%0.01643%0.429CS..EExtended strand (participates in β ladder)trans-90.7-24.8179.9-55.1-70.1000112.1T16 D78 V79 F81 K86 I318 D320T16-Y18 HydrophobicContact CG2-CD1 3.87Å; T16-Y18 HydrophobicContact CG2-CE1 3.47Å; T16-Y18 VanDerWaalsContact CG2-CE1 3.47Å; Y18-D78 PolarHBondContact O-N 2.86Å; Y18-V79 HydrophobicContact CD1-CB 4.31Å; Y18-V79 WeakPolarHBondContact CD1-O 3.5Å; Y18-F81 HydrophobicContact CD1-CB 3.67Å; Y18-F81 AromaticContact CD1-CD1 3.57Å; Y18-F81 HydrophobicContact CD1-CD1 3.57Å; Y18-F81 HydrophobicContact CD1-CD2 4.29Å; Y18-F81 HydrophobicContact CD1-CE1 4.26Å; Y18-F81 AromaticContact CD1-CG 3.59Å; Y18-F81 HydrophobicContact CD1-CG 3.59Å; Y18-F81 AromaticContact CD2-CD1 3.84Å; Y18-F81 HydrophobicContact CD2-CD1 3.84Å; Y18-F81 AromaticContact CD2-CD2 3.98Å; Y18-F81 HydrophobicContact CD2-CD2 3.98Å; Y18-F81 AromaticContact CD2-CE1 3.72Å; Y18-F81 HydrophobicContact CD2-CE1 3.72Å; Y18-F81 AromaticContact CD2-CE2 3.86Å; Y18-F81 HydrophobicContact CD2-CE2 3.86Å; Y18-F81 AromaticContact CD2-CG 3.97Å; Y18-F81 HydrophobicContact CD2-CG 3.97Å; Y18-F81 AromaticContact CD2-CZ 3.72Å; Y18-F81 HydrophobicContact CD2-CZ 3.72Å; Y18-F81 HydrophobicContact CE1-CB 3.32Å; Y18-F81 AromaticContact CE1-CD1 3.98Å; Y18-F81 HydrophobicContact CE1-CD1 3.98Å; Y18-F81 AromaticContact CE1-CD2 3.9Å; Y18-F81 HydrophobicContact CE1-CD2 3.9Å; Y18-F81 AromaticContact CE1-CG 3.48Å; Y18-F81 HydrophobicContact CE1-CG 3.48Å; Y18-F81 VanDerWaalsContact CE1-CG 3.48Å; Y18-F81 HydrophobicContact CE2-CD1 4.22Å; Y18-F81 AromaticContact CE2-CD2 3.55Å; Y18-F81 HydrophobicContact CE2-CD2 3.55Å; Y18-F81 HydrophobicContact CE2-CE1 4.29Å; Y18-F81 AromaticContact CE2-CE2 3.63Å; Y18-F81 HydrophobicContact CE2-CE2 3.63Å; Y18-F81 AromaticContact CE2-CG 3.87Å; Y18-F81 HydrophobicContact CE2-CG 3.87Å; Y18-F81 HydrophobicContact CE2-CZ 4.01Å; Y18-F81 HydrophobicContact CG-CB 4.42Å; Y18-F81 AromaticContact CG-CD1 3.5Å; Y18-F81 HydrophobicContact CG-CD1 3.5Å; Y18-F81 VanDerWaalsContact CG-CD1 3.5Å; Y18-F81 HydrophobicContact CG-CD2 4.33Å; Y18-F81 AromaticContact CG-CE1 3.7Å; Y18-F81 HydrophobicContact CG-CE1 3.7Å; Y18-F81 HydrophobicContact CG-CE2 4.5Å; Y18-F81 AromaticContact CG-CG 3.85Å; Y18-F81 HydrophobicContact CG-CG 3.85Å; Y18-F81 HydrophobicContact CG-CZ 4.2Å; Y18-F81 AromaticContact CZ-CD2 3.5Å; Y18-F81 AromaticContact CZ-CG 3.63Å; Y18-K86 PolarHBondContact OH-NZ 3.36Å; Y18-I318 HydrophobicContact CD2-CG2 4.14Å; Y18-I318 PolarHBondContact N-O 3.2Å; Y18-D320 HydrophobicContact CE2-CB 3.95Å; Y18-D320 PolarHBondContact OH-OD2 2.95Å
19L97.3Very high80.6Confident0 Ų063 Ų630%040%0.395CS..EExtended strand (participates in β ladder)trans-160.3136.3172.5179.569.2000108.9E21 R75 L77 V300 I316 L317 I318L19-E21 HydrophobicContact CD1-CB 4.41Å; L19-E21 HydrophobicContact CG-CB 4.48Å; L19-R75 VanDerWaalsContact CD1-CZ 3.43Å; L19-L77 HydrophobicContact CB-CD2 3.94Å; L19-L77 HydrophobicContact CD2-CD2 3.92Å; L19-L77 HydrophobicContact CG-CD2 4.47Å; L19-V300 HydrophobicContact CD2-CB 4.48Å; L19-V300 HydrophobicContact CD2-CG1 3.63Å; L19-I316 HydrophobicContact CD2-CG2 3.86Å; L19-L317 WeakPolarHBondContact O-CA 3.5Å; L19-I318 HydrophobicContact CB-CB 4.18Å; L19-I318 HydrophobicContact CB-CD1 4.28Å; L19-I318 HydrophobicContact CB-CG1 4.36Å; L19-I318 HydrophobicContact CD2-CD1 4Å; L19-I318 PolarHBondContact N-O 3.26Å; L19-I318 PolarHBondContact O-N 3.34Å
20D95.5Very high83.7Confident52 Ų5263 Ų6328%0.27839%0.385SS..EExtended strand (participates in β ladder)trans-136102.3164.5-173.1-6.4000106.6V17 R22 I316 L317V17-D20 HydrophobicContact CG1-CB 3.87Å; D20-R22 WeakPolarHBondContact OD1-CG 3.34Å; D20-R22 IonicContact OD1-CZ 3.78Å; D20-R22 IonicContact OD1-NE 3.78Å; D20-R22 PolarHBondContact OD1-NE 2.91Å; D20-R22 IonicContact OD1-NH2 3.3Å; D20-R22 IonicContact OD2-CZ 2.75Å; D20-R22 IonicContact OD2-NE 2.67Å; D20-R22 PolarHBondContact OD2-NE 2.92Å; D20-R22 IonicContact OD2-NH2 3.11Å; D20-R22 PolarHBondContact OD2-NH2 2.8Å; D20-I316 WeakPolarHBondContact CA-O 3.41Å; D20-L317 HydrophobicContact CB-CD1 4.15Å
21E96.4Very high86.4Confident3 Ų367 Ų671%0.01439%0.393CS..EExtended strand (participates in β ladder)trans-115.1118.3179.5176.173.4-99.100109.6L19 F23 R32 W33 R75 N315 I316L19-E21 HydrophobicContact CD1-CB 4.41Å; L19-E21 HydrophobicContact CG-CB 4.48Å; E21-F23 HydrophobicContact CG-CD1 4.2Å; E21-F23 HydrophobicContact CG-CD2 4.06Å; E21-F23 HydrophobicContact CG-CE1 3.84Å; E21-F23 HydrophobicContact CG-CE2 3.68Å; E21-F23 HydrophobicContact CG-CG 4.31Å; E21-F23 HydrophobicContact CG-CZ 3.56Å; E21-F23 PolarHBondContact OE1-N 3.29Å; E21-R32 IonicContact OE1-CZ 2.91Å; E21-R32 IonicContact OE1-NE 3.55Å; E21-R32 IonicContact OE1-NH2 3.58Å; E21-R32 PolarHBondContact OE1-NH2 3.42Å; E21-R32 IonicContact OE2-CZ 2.78Å; E21-R32 IonicContact OE2-NE 2.81Å; E21-R32 PolarHBondContact OE2-NE 3.03Å; E21-R32 VanDerWaalsContact OE2-NE 3.11Å; E21-R32 IonicContact OE2-NH2 2.62Å; E21-W33 HydrophobicContact CG-CZ2 4.16Å; E21-W33 PolarHBondContact OE2-NE1 3.21Å; E21-R75 IonicContact OE2-CZ 3.08Å; E21-R75 IonicContact OE2-NH1 3.5Å; E21-R75 PolarHBondContact OE2-NH1 3.4Å; E21-N315 CarbonylContact O-C 3.52Å; E21-N315 WeakPolarHBondContact O-CA 3.4Å; E21-N315 PolarHBondContact O-N 3.44Å; E21-I316 HydrophobicContact CB-CB 4.23Å; E21-I316 PolarHBondContact N-O 2.75Å; E21-I316 PolarHBondContact O-N 3.14Å
22R94.5Very high89.2Confident75 Ų7565.2 Ų65.228%0.28337%0.367SS..  trans-123.60.3-176.5-54.8-173.2-172.8-168.84.3113.7D20 D24 D314D20-R22 WeakPolarHBondContact OD1-CG 3.34Å; D20-R22 IonicContact OD1-CZ 3.78Å; D20-R22 IonicContact OD1-NE 3.78Å; D20-R22 PolarHBondContact OD1-NE 2.91Å; D20-R22 IonicContact OD1-NH2 3.3Å; D20-R22 IonicContact OD2-CZ 2.75Å; D20-R22 IonicContact OD2-NE 2.67Å; D20-R22 PolarHBondContact OD2-NE 2.92Å; D20-R22 IonicContact OD2-NH2 3.11Å; D20-R22 PolarHBondContact OD2-NH2 2.8Å; R22-D24 HydrophobicContact CB-CB 4.36Å; R22-D24 PolarHBondContact O-N 3.46Å; R22-D314 WeakPolarHBondContact CA-OD1 3.39Å
23F95.8Very high91.7Very high0 Ų058.2 Ų58.20%033%0.329CS..  trans49.528.6-179.5-54.1-81.1000114.7E21 W29 W33 V47 L62 D314 I316E21-F23 HydrophobicContact CG-CD1 4.2Å; E21-F23 HydrophobicContact CG-CD2 4.06Å; E21-F23 HydrophobicContact CG-CE1 3.84Å; E21-F23 HydrophobicContact CG-CE2 3.68Å; E21-F23 HydrophobicContact CG-CG 4.31Å; E21-F23 HydrophobicContact CG-CZ 3.56Å; E21-F23 PolarHBondContact OE1-N 3.29Å; F23-W29 HydrophobicContact CD1-CB 3.76Å; F23-W29 HydrophobicContact CD1-CG 4.12Å; F23-W29 HydrophobicContact CE1-CB 4.14Å; F23-W33 AromaticContact CE1-CD1 3.97Å; F23-W33 AromaticContact CE1-CE2 3.9Å; F23-W33 HydrophobicContact CE1-CZ2 4.36Å; F23-W33 AromaticContact CE1-NE1 3.44Å; F23-W33 AromaticContact CZ-CE2 3.83Å; F23-W33 AromaticContact CZ-CZ2 3.81Å; F23-W33 HydrophobicContact CZ-CZ2 3.81Å; F23-W33 AromaticContact CZ-NE1 3.78Å; F23-V47 HydrophobicContact CB-CG1 3.8Å; F23-V47 HydrophobicContact CB-CG2 4.14Å; F23-V47 HydrophobicContact CD1-CG2 3.67Å; F23-V47 HydrophobicContact CE1-CG2 4.38Å; F23-V47 HydrophobicContact CG-CG2 4.12Å; F23-L62 HydrophobicContact CE1-CB 4.15Å; F23-L62 HydrophobicContact CE2-CB 4.2Å; F23-L62 HydrophobicContact CZ-CB 3.83Å; F23-D314 WeakPolarHBondContact CD2-OD1 3.39Å; F23-I316 HydrophobicContact CE2-CD1 4.18Å; F23-I316 HydrophobicContact CZ-CD1 4.24Å
24D92.5Very high93.5Very high103 Ų10356.5 Ų56.555%0.55131%0.31SS*.  trans-94.83.7-17461.4-8.3000113.1R22R22-D24 HydrophobicContact CB-CB 4.36Å; R22-D24 PolarHBondContact O-N 3.46Å
25D94.1Very high94.9Very high63 Ų6355 Ų5534%0.33729%0.292SS..SBendtrans-11333.4-174.665.5-6.5000113.9D27 S28 R32D25-D27 PolarHBondContact O-N 3.35Å; D25-S28 WeakPolarHBondContact O-CB 3.39Å; D25-S28 PolarHBondContact O-N 2.97Å; D25-S28 PolarHBondContact O-OG 3.05Å; D25-R32 VanDerWaalsContact CG-NH2 3.33Å; D25-R32 IonicContact OD1-CZ 3.62Å; D25-R32 IonicContact OD1-NH1 3.73Å; D25-R32 IonicContact OD1-NH2 3.66Å; D25-R32 PolarHBondContact OD1-NH2 3.27Å; D25-R32 IonicContact OD2-CZ 2.67Å; D25-R32 VanDerWaalsContact OD2-CZ 3.25Å; D25-R32 IonicContact OD2-NH1 3.73Å; D25-R32 PolarHBondContact OD2-NH1 3.31Å; D25-R32 IonicContact OD2-NH2 3.25Å; D25-R32 PolarHBondContact OD2-NH2 3.01Å; D25-R32 VanDerWaalsContact OD2-NH2 3.08Å
26G92.8Very high95.6Very high45 Ų4551.9 Ų51.946%0.46427%0.272SS..THydrogen-bonded Turntrans71.9-124.8172.700000112.2
27D95.4Very high95.6Very high102 Ų10254.2 Ų54.255%0.54528%0.282SS..THydrogen-bonded Turntrans-90.4-0.7-177.6-94.2-11.5000113.7D25 W29 K30D25-D27 PolarHBondContact O-N 3.35Å; D27-W29 PolarHBondContact O-N 3.24Å; D27-W29 VanDerWaalsContact O-N 3.13Å; D27-K30 HydrophobicContact CB-CD 4.24Å; D27-K30 VanDerWaalsContact O-CB 3.3Å; D27-K30 WeakPolarHBondContact O-CB 3.31Å; D27-K30 WeakPolarHBondContact O-CG 3.42Å; D27-K30 PolarHBondContact O-N 3.42Å; D27-K30 WeakPolarHBondContact OD1-CE 3.41Å; D27-K30 IonicContact OD1-NZ 3.78Å; D27-K30 PolarHBondContact OD1-NZ 3.41Å; D27-K30 IonicContact OD2-NZ 3.57Å; D27-K30 PolarHBondContact OD2-NZ 2.98Å
28S96.2Very high95.3Very high47 Ų4755.7 Ų55.733%0.32929%0.286SS..THydrogen-bonded Turntrans-61-24.8-175.9-49.30000113.1D25 K30 E31D25-S28 WeakPolarHBondContact O-CB 3.39Å; D25-S28 PolarHBondContact O-N 2.97Å; D25-S28 PolarHBondContact O-OG 3.05Å; S28-K30 PolarHBondContact O-N 3.43Å; S28-K30 VanDerWaalsContact O-N 3.17Å; S28-E31 WeakPolarHBondContact O-CB 3.45Å; S28-E31 PolarHBondContact O-N 3.17Å; S28-E31 VanDerWaalsContact O-N 3.07Å
29W96.8Very high94.3Very high15 Ų1557.9 Ų57.96%0.05730%0.296CS..Hα-helixtrans-56.4-29.3172.872.2-89.8000113F23 D27 E31 R32 W33 V45 V47 L62F23-W29 HydrophobicContact CD1-CB 3.76Å; F23-W29 HydrophobicContact CD1-CG 4.12Å; F23-W29 HydrophobicContact CE1-CB 4.14Å; D27-W29 PolarHBondContact O-N 3.24Å; D27-W29 VanDerWaalsContact O-N 3.13Å; W29-E31 PolarHBondContact O-N 3.38Å; W29-R32 PolarHBondContact O-N 3.08Å; W29-W33 HydrophobicContact CE3-CB 4.09Å; W29-W33 HydrophobicContact CE3-CG 4.36Å; W29-W33 WeakPolarHBondContact O-CB 3.46Å; W29-W33 PolarHBondContact O-N 3.01Å; W29-V45 HydrophobicContact CH2-CG2 3.75Å; W29-V45 HydrophobicContact CZ3-CG2 4.06Å; W29-V47 HydrophobicContact CD2-CG2 3.72Å; W29-V47 VanDerWaalsContact CE2-CG2 3.46Å; W29-V47 HydrophobicContact CE3-CG2 4.48Å; W29-V47 HydrophobicContact CG-CG2 3.81Å; W29-V47 HydrophobicContact CZ2-CG2 4.04Å; W29-L62 HydrophobicContact CE3-CD1 4.22Å; W29-L62 HydrophobicContact CH2-CD1 4.25Å; W29-L62 HydrophobicContact CZ3-CD1 3.85Å
30K96.7Very high93.2Very high113 Ų11365.2 Ų65.249%0.49133%0.33SS..Hα-helixtrans-64.8-23178.7-63.7175.2-177.8167.60112.8D27 S28D27-K30 HydrophobicContact CB-CD 4.24Å; D27-K30 VanDerWaalsContact O-CB 3.3Å; D27-K30 WeakPolarHBondContact O-CB 3.31Å; D27-K30 WeakPolarHBondContact O-CG 3.42Å; D27-K30 PolarHBondContact O-N 3.42Å; D27-K30 WeakPolarHBondContact OD1-CE 3.41Å; D27-K30 IonicContact OD1-NZ 3.78Å; D27-K30 PolarHBondContact OD1-NZ 3.41Å; D27-K30 IonicContact OD2-NZ 3.57Å; D27-K30 PolarHBondContact OD2-NZ 2.98Å; S28-K30 PolarHBondContact O-N 3.43Å; S28-K30 VanDerWaalsContact O-N 3.17Å
31E96.5Very high92.6Very high177 Ų17767 Ų6783%0.82735%0.345SS*.Hα-helixtrans-82.9-24.1175.7-57.3-176.3174.300111.9S28 W29S28-E31 WeakPolarHBondContact O-CB 3.45Å; S28-E31 PolarHBondContact O-N 3.17Å; S28-E31 VanDerWaalsContact O-N 3.07Å; W29-E31 PolarHBondContact O-N 3.38Å
32R97.1Very high92.4Very high57 Ų5768 Ų6822%0.21535%0.349CS..Hα-helixtrans-96.3-35.9-174.5-54.1-168.5-68.3-95.96.1113.1E21 D25 W29 R75E21-R32 IonicContact OE1-CZ 2.91Å; E21-R32 IonicContact OE1-NE 3.55Å; E21-R32 IonicContact OE1-NH2 3.58Å; E21-R32 PolarHBondContact OE1-NH2 3.42Å; E21-R32 IonicContact OE2-CZ 2.78Å; E21-R32 IonicContact OE2-NE 2.81Å; E21-R32 PolarHBondContact OE2-NE 3.03Å; E21-R32 VanDerWaalsContact OE2-NE 3.11Å; E21-R32 IonicContact OE2-NH2 2.62Å; D25-R32 VanDerWaalsContact CG-NH2 3.33Å; D25-R32 IonicContact OD1-CZ 3.62Å; D25-R32 IonicContact OD1-NH1 3.73Å; D25-R32 IonicContact OD1-NH2 3.66Å; D25-R32 PolarHBondContact OD1-NH2 3.27Å; D25-R32 IonicContact OD2-CZ 2.67Å; D25-R32 VanDerWaalsContact OD2-CZ 3.25Å; D25-R32 IonicContact OD2-NH1 3.73Å; D25-R32 PolarHBondContact OD2-NH1 3.31Å; D25-R32 IonicContact OD2-NH2 3.25Å; D25-R32 PolarHBondContact OD2-NH2 3.01Å; D25-R32 VanDerWaalsContact OD2-NH2 3.08Å; W29-R32 PolarHBondContact O-N 3.08Å; R32-R75 HydrophobicContact CB-CG 4.42Å; R32-R75 WeakPolarHBondContact O-CB 3.39Å; R32-R75 WeakPolarHBondContact O-CG 3.39Å
33W98Very high92.3Very high12 Ų1264.4 Ų64.45%0.04534%0.336CS..EExtended strand (participates in β ladder)trans-95124.8-178.8-72.283.3000111E21 F23 W29 L73 R75 V300 F302 I316E21-W33 HydrophobicContact CG-CZ2 4.16Å; E21-W33 PolarHBondContact OE2-NE1 3.21Å; F23-W33 AromaticContact CE1-CD1 3.97Å; F23-W33 AromaticContact CE1-CE2 3.9Å; F23-W33 HydrophobicContact CE1-CZ2 4.36Å; F23-W33 AromaticContact CE1-NE1 3.44Å; F23-W33 AromaticContact CZ-CE2 3.83Å; F23-W33 AromaticContact CZ-CZ2 3.81Å; F23-W33 HydrophobicContact CZ-CZ2 3.81Å; F23-W33 AromaticContact CZ-NE1 3.78Å; W29-W33 HydrophobicContact CE3-CB 4.09Å; W29-W33 HydrophobicContact CE3-CG 4.36Å; W29-W33 WeakPolarHBondContact O-CB 3.46Å; W29-W33 PolarHBondContact O-N 3.01Å; W33-L73 HydrophobicContact CE3-CB 4.04Å; W33-L73 HydrophobicContact CZ3-CB 4.44Å; W33-R75 HydrophobicContact CD2-CB 3.84Å; W33-R75 HydrophobicContact CE3-CB 4.04Å; W33-R75 HydrophobicContact CG-CB 4.21Å; W33-R75 HydrophobicContact CZ2-CB 4.34Å; W33-R75 HydrophobicContact CZ3-CB 4.41Å; W33-V300 HydrophobicContact CH2-CG1 4.28Å; W33-F302 AromaticContact CH2-CD2 3.88Å; W33-F302 HydrophobicContact CH2-CD2 3.88Å; W33-F302 AromaticContact CH2-CE2 3.5Å; W33-F302 HydrophobicContact CH2-CE2 3.5Å; W33-F302 VanDerWaalsContact CH2-CE2 3.5Å; W33-F302 HydrophobicContact CZ2-CE2 4.48Å; W33-F302 AromaticContact CZ3-CD2 3.68Å; W33-F302 HydrophobicContact CZ3-CD2 3.68Å; W33-F302 AromaticContact CZ3-CE2 3.82Å; W33-F302 HydrophobicContact CZ3-CE2 3.82Å; W33-I316 HydrophobicContact CH2-CD1 3.69Å; W33-I316 HydrophobicContact CZ2-CD1 3.58Å
34V97.1Very high92.3Very high54 Ų5471 Ų7133%0.32736%0.364SS..EExtended strand (participates in β ladder)trans-101.6120.8177.3-178.10000108.4L73 S74 L116V34-L73 WeakPolarHBondContact O-CA 3.48Å; V34-S74 PolarHBondContact N-O 3.47Å; V34-S74 PolarHBondContact O-N 2.85Å; V34-L116 HydrophobicContact CB-CB 3.97Å; V34-L116 HydrophobicContact CG1-CB 4.06Å; V34-L116 HydrophobicContact CG2-CB 4.25Å; V34-L116 HydrophobicContact CG2-CD1 4.23Å
35Q95.6Very high92.5Very high66 Ų6667.5 Ų67.531%0.30835%0.347SS..EExtended strand (participates in β ladder)trans-84.7130.8167.1-169161.422.500109.3Q42 G43 L73Q35-Q42 HydrophobicContact CG-CB 4.2Å; Q35-Q42 HydrophobicContact CG-CG 4.14Å; Q35-Q42 VanDerWaalsContact NE2-CB 3.29Å; Q35-G43 PolarHBondContact NE2-O 3.01Å; Q35-L73 HydrophobicContact CB-CG 4.26Å; Q35-L73 HydrophobicContact CG-CD1 4.37Å; Q35-L73 HydrophobicContact CG-CG 4.25Å
36S96Very high92.6Very high2 Ų268.4 Ų68.41%0.01435%0.349CS..PPolyproline II helixtrans-65.9149.4-177.1-176.80000112.6H38 Q42 Q72 S117 F119S36-H38 WeakPolarHBondContact OG-CB 3.38Å; S36-H38 PolarHBondContact OG-N 3Å; S36-H38 VanDerWaalsContact OG-N 3.08Å; S36-Q42 VanDerWaalsContact O-CG 3.31Å; S36-Q42 WeakPolarHBondContact O-CG 3.18Å; S36-Q72 PolarHBondContact N-O 3.39Å; S36-S117 PolarHBondContact OG-O 3.41Å; S36-F119 WeakPolarHBondContact CB-O 3.41Å; S36-F119 PolarHBondContact OG-N 2.94Å; S36-F119 PolarHBondContact OG-O 3.39Å
37N92.1Very high92.8Very high95 Ų9567.8 Ų67.851%0.50834%0.336SS..SBendtrans-99.51.3171.3-61.6-36.2000112.4H40 S117N37-H40 PolarHBondContact O-NE2 2.84Å; N37-S117 PolarHBondContact N-O 3.46Å
38H87.5Confident92.8Very high85 Ų8563.6 Ų63.639%0.39432%0.317SS..SBendtrans-67.7-45-170.5-166.275.3000113.4S36 E118 N120S36-H38 WeakPolarHBondContact OG-CB 3.38Å; S36-H38 PolarHBondContact OG-N 3Å; S36-H38 VanDerWaalsContact OG-N 3.08Å; H38-E118 IonicContact CE1-OE2 3.03Å; H38-E118 IonicContact CG-OE2 3.64Å; H38-E118 IonicContact ND1-OE2 2.7Å; H38-E118 PolarHBondContact ND1-OE2 2.92Å; H38-N120 HydrophobicContact CB-CB 4.15Å; H38-N120 PolarHBondContact CD2-ND2 2.88Å; H38-N120 PolarHBondContact CE1-ND2 2.76Å; H38-N120 VanDerWaalsContact CE1-ND2 3.31Å; H38-N120 PolarHBondContact ND1-ND2 2.76Å; H38-N120 PolarHBondContact NE2-ND2 2.85Å; H38-N120 VanDerWaalsContact NE2-ND2 3.15Å
39E75.8Confident92.7Very high50 Ų5064.1 Ų64.123%0.23431%0.314CS..SBendtrans-112.3124.9179.2-64.8178.8163.800109.4Q42 Y70 Q72E39-Q42 WeakPolarHBondContact O-CG 3.21Å; E39-Q42 PolarHBondContact O-NE2 3.2Å; E39-Y70 WeakPolarHBondContact OE2-CD1 3.29Å; E39-Y70 VanDerWaalsContact OE2-CD2 3.32Å; E39-Y70 WeakPolarHBondContact OE2-CD2 3.47Å; E39-Q72 PolarHBondContact OE2-NE2 2.97Å
40H74.1Confident92.4Very high153 Ų15364 Ų6471%0.70832%0.317SS*.SBendtrans-112.9136177.7-75.1-52.4000111.8N37N37-H40 PolarHBondContact O-NE2 2.84Å
41P83.5Confident92.1Very high91 Ų9161.8 Ų61.859%0.59131%0.311SS*.SBendcis-89.7135.5-6.932.1-29.6000113.4
42Q92Very high92Very high23 Ų2353.4 Ų53.411%0.10727%0.272CS..PPolyproline II helixtrans-66.3152.7167.7-63.8-70.1-52.300111.3Q35 S36 E39 Y70Q35-Q42 HydrophobicContact CG-CB 4.2Å; Q35-Q42 HydrophobicContact CG-CG 4.14Å; Q35-Q42 VanDerWaalsContact NE2-CB 3.29Å; S36-Q42 VanDerWaalsContact O-CG 3.31Å; S36-Q42 WeakPolarHBondContact O-CG 3.18Å; E39-Q42 WeakPolarHBondContact O-CG 3.21Å; E39-Q42 PolarHBondContact O-NE2 3.2Å; Q42-Y70 PolarHBondContact OE1-O 3.41Å
43G93.8Very high91.8Very high0 Ų053.4 Ų53.40%027%0.272CS..PPolyproline II helixtrans-72.9144.8173.300000112.8Q35 E66 Y70 Y71Q35-G43 PolarHBondContact NE2-O 3.01Å; G43-E66 WeakPolarHBondContact CA-OE2 3.48Å; G43-Y70 PolarHBondContact N-O 3.1Å; G43-Y71 VanDerWaalsContact C-CE1 3.48Å; G43-Y71 WeakPolarHBondContact O-CE1 3.2Å
44K95.4Very high91.4Very high138 Ų13853.8 Ų53.860%0.628%0.278SS*.PPolyproline II helixtrans-67.8137.3174.6-68.6175-175.5172.60111.3M65 E66 Y71K44-M65 HydrophobicContact CB-CB 4.31Å; K44-M65 VanDerWaalsContact O-CB 3.26Å; K44-M65 WeakPolarHBondContact O-CB 3.45Å; K44-M65 WeakPolarHBondContact O-CG 3.26Å; K44-M65 PolarHBondContact O-N 3.44Å; K44-E66 HydrophobicContact CB-CG 4.48Å; K44-E66 PolarHBondContact N-OE2 3.13Å; K44-Y71 WeakPolarHBondContact O-CE1 3.45Å
45V96Very high91.1Very high29 Ų2953.8 Ų53.818%0.17628%0.276CS..EExtended strand (participates in β ladder)trans-113.9153.4172.7-69.40000111.5W29 L62 Q63 Y71 L73W29-V45 HydrophobicContact CH2-CG2 3.75Å; W29-V45 HydrophobicContact CZ3-CG2 4.06Å; V45-L62 HydrophobicContact CB-CD1 4Å; V45-L62 HydrophobicContact CG1-CD1 4.42Å; V45-L62 HydrophobicContact CG2-CD1 4.34Å; V45-Q63 CarbonylContact C-O 3.54Å; V45-Q63 VanDerWaalsContact CA-O 3.27Å; V45-Q63 WeakPolarHBondContact CA-O 3.48Å; V45-Y71 HydrophobicContact CG1-CD1 3.58Å; V45-Y71 HydrophobicContact CG1-CE1 3.82Å; V45-L73 HydrophobicContact CB-CD2 4.41Å; V45-L73 HydrophobicContact CG1-CD1 3.61Å; V45-L73 HydrophobicContact CG1-CD2 4.12Å; V45-L73 HydrophobicContact CG2-CD2 3.71Å
46Q96.1Very high90.8Very high82 Ų8252.9 Ų52.938%0.38328%0.276SS..EExtended strand (participates in β ladder)trans-137.9171.7167.273.7-176.816.100110.1L62 Q63 M65Q46-L62 CarbonylContact O-C 3.21Å; Q46-L62 WeakPolarHBondContact O-CA 3.38Å; Q46-Q63 HydrophobicContact CG-CB 4Å; Q46-Q63 PolarHBondContact N-O 3.36Å; Q46-Q63 PolarHBondContact O-N 2.99Å; Q46-M65 HydrophobicContact CB-CG 4.35Å; Q46-M65 HydrophobicContact CB-SD 4.42Å; Q46-M65 VanDerWaalsContact CD-CE 3.42Å; Q46-M65 HydrophobicContact CG-CE 4.29Å; Q46-M65 HydrophobicContact CG-CG 3.98Å; Q46-M65 HydrophobicContact CG-SD 3.44Å; Q46-M65 WeakPolarHBondContact CG-SD 3.29Å; Q46-M65 PolarHBondContact NE2-SD 3.44Å; Q46-M65 VanDerWaalsContact NE2-SD 3.36Å
47V97Very high90.4Very high33 Ų3358.5 Ų58.520%0.230%0.302CS..EExtended strand (participates in β ladder)trans-107.9133.4164.4163.90000108.6F23 W29 K60 G61 L62F23-V47 HydrophobicContact CB-CG1 3.8Å; F23-V47 HydrophobicContact CB-CG2 4.14Å; F23-V47 HydrophobicContact CD1-CG2 3.67Å; F23-V47 HydrophobicContact CE1-CG2 4.38Å; F23-V47 HydrophobicContact CG-CG2 4.12Å; W29-V47 HydrophobicContact CD2-CG2 3.72Å; W29-V47 VanDerWaalsContact CE2-CG2 3.46Å; W29-V47 HydrophobicContact CE3-CG2 4.48Å; W29-V47 HydrophobicContact CG-CG2 3.81Å; W29-V47 HydrophobicContact CZ2-CG2 4.04Å; V47-K60 HydrophobicContact CG1-CB 3.86Å; V47-G61 CarbonylContact C-O 3.54Å; V47-G61 VanDerWaalsContact CA-O 3.29Å; V47-G61 WeakPolarHBondContact CA-O 3.47Å; V47-L62 HydrophobicContact CG2-CD1 4.5Å
48G95.7Very high90.2Very high13 Ų1358 Ų5813%0.13430%0.298CS..EExtended strand (participates in β ladder)trans-174.6175.4177.300000112.6G61 Q63G48-G61 PolarHBondContact N-O 3.23Å; G48-G61 PolarHBondContact O-N 3.04Å; G48-G61 VanDerWaalsContact O-O 3.11Å; G48-Q63 PolarHBondContact O-NE2 2.91Å
49H93Very high90.4Very high58 Ų5855.1 Ų55.127%0.26929%0.286SS..  trans-93.5-9.9-174.957.256.9000114.9Y53 D59H49-Y53 HydrophobicContact CB-CD1 4.05Å; H49-Y53 HydrophobicContact CB-CG 4.18Å; H49-Y53 AromaticContact CE1-CD1 3.52Å; H49-Y53 AromaticContact CE1-CE1 3.19Å; H49-Y53 WeakPolarHBondContact CE1-CE1 3.37Å; H49-Y53 AromaticContact CG-CD1 3.48Å; H49-Y53 VanDerWaalsContact CG-CD1 3.48Å; H49-Y53 AromaticContact CG-CE1 3.88Å; H49-Y53 AromaticContact ND1-CD1 3.05Å; H49-Y53 WeakPolarHBondContact ND1-CD1 3.35Å; H49-Y53 AromaticContact ND1-CE1 3.29Å; H49-Y53 VanDerWaalsContact ND1-CE1 3.29Å; H49-Y53 WeakPolarHBondContact ND1-CE1 3.5Å; H49-Y53 AromaticContact NE2-CE1 3.74Å; H49-D59 VanDerWaalsContact CA-O 3.23Å; H49-D59 WeakPolarHBondContact CA-O 3.44Å; H49-D59 HydrophobicContact CB-CB 4.48Å
50G92.1Very high91.3Very high13 Ų1355.2 Ų55.213%0.13429%0.285CS..  trans81.8-168.2-177.100000113.4F52 Q97G50-F52 VanDerWaalsContact C-N 3.3Å; G50-F52 PolarHBondContact O-N 3.25Å; G50-Q97 VanDerWaalsContact C-OE1 3.3Å
51D90.6Very high92.3Very high67 Ų6748 Ų4836%0.35825%0.252SS..SBendtrans-65.3-32.2-173.6-90.4-5000113.2R98 M347D51-R98 IonicContact OD2-NH2 2.62Å; D51-M347 WeakPolarHBondContact O-CE 3.23Å
52F92.9Very high93Very high1 Ų143.9 Ų43.90%0.00423%0.225CC..  trans-142158.6-179.565.1-81.1000109.8G50 K95 E164 Y165 E340 M343 K344 M347G50-F52 VanDerWaalsContact C-N 3.3Å; G50-F52 PolarHBondContact O-N 3.25Å; F52-K95 PolarHBondContact O-NZ 3.19Å; F52-E164 HydrophobicContact CE1-CB 4.49Å; F52-E164 HydrophobicContact CZ-CB 4.07Å; F52-E164 WeakPolarHBondContact CZ-O 3.45Å; F52-Y165 HydrophobicContact CE2-CD1 4.01Å; F52-Y165 HydrophobicContact CE2-CE1 4.26Å; F52-Y165 HydrophobicContact CZ-CD1 4.47Å; F52-E340 HydrophobicContact CD2-CG 3.63Å; F52-E340 HydrophobicContact CE2-CG 3.62Å; F52-M343 HydrophobicContact CB-CG 4.29Å; F52-K344 HydrophobicContact CD1-CD 3.68Å; F52-K344 HydrophobicContact CD2-CB 3.71Å; F52-K344 HydrophobicContact CD2-CD 4.1Å; F52-K344 HydrophobicContact CD2-CG 4.23Å; F52-K344 HydrophobicContact CE1-CD 3.66Å; F52-K344 VanDerWaalsContact CE1-CE 3.49Å; F52-K344 HydrophobicContact CE1-CG 4.38Å; F52-K344 HydrophobicContact CE2-CB 3.78Å; F52-K344 HydrophobicContact CE2-CD 4.07Å; F52-K344 HydrophobicContact CE2-CG 3.99Å; F52-K344 HydrophobicContact CG-CB 4.22Å; F52-K344 HydrophobicContact CG-CD 3.87Å; F52-K344 HydrophobicContact CZ-CB 4.33Å; F52-K344 HydrophobicContact CZ-CD 3.82Å; F52-K344 HydrophobicContact CZ-CG 4.03Å; F52-M347 HydrophobicContact CB-CE 4.41Å; F52-M347 HydrophobicContact CB-SD 3.56Å; F52-M347 VanDerWaalsContact CB-SD 3.56Å
53Y92.8Very high93.2Very high57 Ų5743.2 Ų43.222%0.22422%0.222CC..  trans-162.3167.6-170.943.7-89.8000109.8H49 P56 M343H49-Y53 HydrophobicContact CB-CD1 4.05Å; H49-Y53 HydrophobicContact CB-CG 4.18Å; H49-Y53 AromaticContact CE1-CD1 3.52Å; H49-Y53 AromaticContact CE1-CE1 3.19Å; H49-Y53 WeakPolarHBondContact CE1-CE1 3.37Å; H49-Y53 AromaticContact CG-CD1 3.48Å; H49-Y53 VanDerWaalsContact CG-CD1 3.48Å; H49-Y53 AromaticContact CG-CE1 3.88Å; H49-Y53 AromaticContact ND1-CD1 3.05Å; H49-Y53 WeakPolarHBondContact ND1-CD1 3.35Å; H49-Y53 AromaticContact ND1-CE1 3.29Å; H49-Y53 VanDerWaalsContact ND1-CE1 3.29Å; H49-Y53 WeakPolarHBondContact ND1-CE1 3.5Å; H49-Y53 AromaticContact NE2-CE1 3.74Å; Y53-P56 HydrophobicContact CD2-CB 3.86Å; Y53-P56 HydrophobicContact CD2-CG 4.29Å; Y53-P56 HydrophobicContact CE2-CB 3.48Å; Y53-P56 VanDerWaalsContact CE2-CB 3.48Å; Y53-P56 HydrophobicContact CE2-CG 3.79Å; Y53-M343 HydrophobicContact CD1-CE 3.99Å; Y53-M343 HydrophobicContact CD2-CE 4.15Å; Y53-M343 HydrophobicContact CD2-SD 4.07Å; Y53-M343 HydrophobicContact CE1-CE 3.63Å; Y53-M343 HydrophobicContact CE2-CE 3.8Å; Y53-M343 HydrophobicContact CE2-SD 4.08Å; Y53-M343 HydrophobicContact CG-CE 4.26Å; Y53-M343 HydrophobicContact CG-SD 4.4Å; Y53-M343 WeakPolarHBondContact O-CB 3.47Å
54A90.9Very high93.3Very high19 Ų1943.4 Ų43.416%0.15722%0.223CC..SBendtrans-87.9-47.2166.500000111.1D59 L336 I339 E340A54-D59 VanDerWaalsContact CA-OD2 3.28Å; A54-D59 WeakPolarHBondContact CA-OD2 3.36Å; A54-D59 VanDerWaalsContact CB-OD2 3.26Å; A54-D59 WeakPolarHBondContact CB-OD2 3.47Å; A54-D59 PolarHBondContact N-OD2 2.78Å; A54-L336 HydrophobicContact CB-CB 3.8Å; A54-L336 HydrophobicContact CB-CD2 3.69Å; A54-L336 HydrophobicContact CB-CG 4.33Å; A54-L336 VanDerWaalsContact CB-O 3.24Å; A54-L336 WeakPolarHBondContact CB-O 3.15Å; A54-I339 HydrophobicContact CB-CB 3.86Å; A54-I339 HydrophobicContact CB-CG2 3.96Å; A54-E340 HydrophobicContact CB-CB 4.17Å
55D89.9Confident93.2Very high54 Ų5440.6 Ų40.629%0.28921%0.213SC..  trans-137119.9179.6-171.5-55.4000109.8E57 I58 D59 L336D55-E57 PolarHBondContact O-N 2.99Å; D55-E57 PolarHBondContact OD1-N 2.92Å; D55-I58 HydrophobicContact CB-CB 4.06Å; D55-I58 HydrophobicContact CB-CD1 4.23Å; D55-I58 HydrophobicContact CB-CG1 4.27Å; D55-I58 PolarHBondContact O-N 2.89Å; D55-I58 PolarHBondContact OD1-N 2.84Å; D55-D59 PolarHBondContact N-OD2 2.91Å; D55-D59 VanDerWaalsContact O-CB 3.28Å; D55-D59 WeakPolarHBondContact O-CB 3.4Å; D55-D59 VanDerWaalsContact O-CG 3.32Å; D55-D59 PolarHBondContact O-N 3.49Å; D55-L336 HydrophobicContact CB-CD2 4.38Å
56P90.5Very high93.2Very high47 Ų4742 Ų4231%0.30522%0.218SC..THydrogen-bonded Turntrans-68.8-19-174.326.6-32.2000114.2Y53 K60Y53-P56 HydrophobicContact CD2-CB 3.86Å; Y53-P56 HydrophobicContact CD2-CG 4.29Å; Y53-P56 HydrophobicContact CE2-CB 3.48Å; Y53-P56 VanDerWaalsContact CE2-CB 3.48Å; Y53-P56 HydrophobicContact CE2-CG 3.79Å; P56-K60 WeakPolarHBondContact O-CE 3.3Å
57E87.8Confident93Very high121 Ų12140.7 Ų40.757%0.56522%0.218SC*.THydrogen-bonded Turntrans-91.6-34.7178.8-65.3-55.2134.200111.9D55 K60D55-E57 PolarHBondContact O-N 2.99Å; D55-E57 PolarHBondContact OD1-N 2.92Å; E57-K60 IonicContact OE1-NZ 3.91Å; E57-K60 IonicContact OE2-NZ 3.68Å; E57-K60 PolarHBondContact OE2-NZ 3.13Å
58I87.5Confident92.6Very high84 Ų8444.8 Ų44.843%0.43123%0.233SC..THydrogen-bonded Turntrans-86.7-40.6-177.9-57.7173.8000111.6D55 K60 L336D55-I58 HydrophobicContact CB-CB 4.06Å; D55-I58 HydrophobicContact CB-CD1 4.23Å; D55-I58 HydrophobicContact CB-CG1 4.27Å; D55-I58 PolarHBondContact O-N 2.89Å; D55-I58 PolarHBondContact OD1-N 2.84Å; I58-K60 PolarHBondContact O-N 2.99Å; I58-L336 HydrophobicContact CG2-CD1 4.43Å
59D90.4Very high92.5Very high25 Ų2548.3 Ų48.313%0.13424%0.242CC..SBendtrans-82.925-171.9-58.1-30.7000113.2H49 A54 D55H49-D59 VanDerWaalsContact CA-O 3.23Å; H49-D59 WeakPolarHBondContact CA-O 3.44Å; H49-D59 HydrophobicContact CB-CB 4.48Å; A54-D59 VanDerWaalsContact CA-OD2 3.28Å; A54-D59 WeakPolarHBondContact CA-OD2 3.36Å; A54-D59 VanDerWaalsContact CB-OD2 3.26Å; A54-D59 WeakPolarHBondContact CB-OD2 3.47Å; A54-D59 PolarHBondContact N-OD2 2.78Å; D55-D59 PolarHBondContact N-OD2 2.91Å; D55-D59 VanDerWaalsContact O-CB 3.28Å; D55-D59 WeakPolarHBondContact O-CB 3.4Å; D55-D59 VanDerWaalsContact O-CG 3.32Å; D55-D59 PolarHBondContact O-N 3.49Å
60K94.6Very high92.4Very high52 Ų5250.1 Ų50.123%0.22625%0.247CC..  trans-77.3130176.1-73.3174.4-176.6157.50108.9V47 P56 E57 I58 D314V47-K60 HydrophobicContact CG1-CB 3.86Å; P56-K60 WeakPolarHBondContact O-CE 3.3Å; E57-K60 IonicContact OE1-NZ 3.91Å; E57-K60 IonicContact OE2-NZ 3.68Å; E57-K60 PolarHBondContact OE2-NZ 3.13Å; I58-K60 PolarHBondContact O-N 2.99Å; K60-D314 VanDerWaalsContact O-CG 3.24Å
61G96.5Very high92.5Very high0 Ų049.7 Ų49.70%024%0.242CC..EExtended strand (participates in β ladder)trans-144170.5174.600000112.6V47 G48 Q63 F313V47-G61 CarbonylContact C-O 3.54Å; V47-G61 VanDerWaalsContact CA-O 3.29Å; V47-G61 WeakPolarHBondContact CA-O 3.47Å; G48-G61 PolarHBondContact N-O 3.23Å; G48-G61 PolarHBondContact O-N 3.04Å; G48-G61 VanDerWaalsContact O-O 3.11Å; G61-Q63 PolarHBondContact O-N 2.67Å; G61-F313 CarbonylContact C-O 3.59Å; G61-F313 WeakPolarHBondContact CA-O 3.23Å
62L97.6Very high92.8Very high6 Ų646.5 Ų46.53%0.03123%0.225CC..EExtended strand (participates in β ladder)trans-66.1127.8177.3-17374.3000110.4F23 W29 V45 Q46 V47 L73 F302 F313F23-L62 HydrophobicContact CE1-CB 4.15Å; F23-L62 HydrophobicContact CE2-CB 4.2Å; F23-L62 HydrophobicContact CZ-CB 3.83Å; W29-L62 HydrophobicContact CE3-CD1 4.22Å; W29-L62 HydrophobicContact CH2-CD1 4.25Å; W29-L62 HydrophobicContact CZ3-CD1 3.85Å; V45-L62 HydrophobicContact CB-CD1 4Å; V45-L62 HydrophobicContact CG1-CD1 4.42Å; V45-L62 HydrophobicContact CG2-CD1 4.34Å; Q46-L62 CarbonylContact O-C 3.21Å; Q46-L62 WeakPolarHBondContact O-CA 3.38Å; V47-L62 HydrophobicContact CG2-CD1 4.5Å; L62-L73 HydrophobicContact CD1-CD2 4.36Å; L62-L73 HydrophobicContact CD2-CD2 4.36Å; L62-F302 HydrophobicContact CD2-CD2 4.12Å; L62-F302 HydrophobicContact CD2-CE2 4.29Å; L62-F313 HydrophobicContact CB-CB 4.39Å; L62-F313 PolarHBondContact N-O 3.47Å; L62-F313 PolarHBondContact O-N 3.47Å
63Q96.5Very high93Very high9 Ų946.6 Ų46.64%0.04223%0.225CC..EExtended strand (participates in β ladder)trans-125.2121.2-178.5-66.3-171.141.800111.5V45 Q46 G48 G61 M65 V312V45-Q63 CarbonylContact C-O 3.54Å; V45-Q63 VanDerWaalsContact CA-O 3.27Å; V45-Q63 WeakPolarHBondContact CA-O 3.48Å; Q46-Q63 HydrophobicContact CG-CB 4Å; Q46-Q63 PolarHBondContact N-O 3.36Å; Q46-Q63 PolarHBondContact O-N 2.99Å; G48-Q63 PolarHBondContact O-NE2 2.91Å; G61-Q63 PolarHBondContact O-N 2.67Å; Q63-M65 HydrophobicContact CB-SD 4.17Å; Q63-V312 HydrophobicContact CG-CB 4.25Å; Q63-V312 HydrophobicContact CG-CG1 4.06Å; Q63-V312 HydrophobicContact CG-CG2 3.89Å
64P95.2Very high93.3Very high4 Ų443.9 Ų43.93%0.02622%0.215CC..EExtended strand (participates in β ladder)trans-58.5141.4157.8-21.535000110.8Y71 I306 P309 I311 F313P64-Y71 HydrophobicContact CB-CD1 4Å; P64-Y71 HydrophobicContact CB-CD2 4.22Å; P64-Y71 HydrophobicContact CB-CE1 3.57Å; P64-Y71 HydrophobicContact CB-CE2 3.81Å; P64-Y71 HydrophobicContact CB-CG 4.3Å; P64-Y71 VanDerWaalsContact CB-CZ 3.46Å; P64-Y71 HydrophobicContact CG-CD1 4.41Å; P64-Y71 HydrophobicContact CG-CE1 4.43Å; P64-I306 HydrophobicContact CB-CD1 3.69Å; P64-I306 HydrophobicContact CB-CG2 4.49Å; P64-I306 HydrophobicContact CG-CD1 3.3Å; P64-P309 HydrophobicContact CB-CB 4.08Å; P64-P309 WeakPolarHBondContact O-CB 3.46Å; P64-P309 VanDerWaalsContact O-O 3.06Å; P64-I311 WeakPolarHBondContact CD-O 3.44Å; P64-F313 HydrophobicContact CG-CE2 4.09Å
65M94.7Very high93.6Very high79 Ų7943.9 Ų43.939%0.38921%0.211SC..  trans-117.7-15.6-175.1-61.9-55.4-66.900115.3K44 Q46 Q63 Y71K44-M65 HydrophobicContact CB-CB 4.31Å; K44-M65 VanDerWaalsContact O-CB 3.26Å; K44-M65 WeakPolarHBondContact O-CB 3.45Å; K44-M65 WeakPolarHBondContact O-CG 3.26Å; K44-M65 PolarHBondContact O-N 3.44Å; Q46-M65 HydrophobicContact CB-CG 4.35Å; Q46-M65 HydrophobicContact CB-SD 4.42Å; Q46-M65 VanDerWaalsContact CD-CE 3.42Å; Q46-M65 HydrophobicContact CG-CE 4.29Å; Q46-M65 HydrophobicContact CG-CG 3.98Å; Q46-M65 HydrophobicContact CG-SD 3.44Å; Q46-M65 WeakPolarHBondContact CG-SD 3.29Å; Q46-M65 PolarHBondContact NE2-SD 3.44Å; Q46-M65 VanDerWaalsContact NE2-SD 3.36Å; Q63-M65 HydrophobicContact CB-SD 4.17Å; M65-Y71 PolarHBondContact N-OH 3.02Å
66E94.2Very high94Very high57 Ų5748.1 Ų48.127%0.26623%0.227SC..SBendtrans-125.4136-171.9-64.8178.2124.500111.4G43 K44 R69 Y71G43-E66 WeakPolarHBondContact CA-OE2 3.48Å; K44-E66 HydrophobicContact CB-CG 4.48Å; K44-E66 PolarHBondContact N-OE2 3.13Å; E66-R69 HydrophobicContact CB-CG 3.76Å; E66-Y71 WeakPolarHBondContact CA-OH 3.48Å; E66-Y71 PolarHBondContact N-OH 3.45Å; E66-Y71 PolarHBondContact O-OH 3.3Å
67S91.8Very high94.4Very high55 Ų5546.3 Ų46.339%0.38521%0.214SC..SBendtrans-74.8150.9173.1-67.20000112.2I307 P309S67-I307 WeakPolarHBondContact CA-O 3.43Å; S67-I307 WeakPolarHBondContact CB-O 3.49Å; S67-I307 PolarHBondContact OG-O 3.24Å; S67-P309 WeakPolarHBondContact OG-CD 3.46Å
68F90.3Very high94.8Very high119 Ų11945 Ų4552%0.52221%0.211SC..SBendtrans56.450.3176.9-49.8-80.5000112W305 I306 I307F68-W305 HydrophobicContact CB-CH2 3.94Å; F68-W305 HydrophobicContact CB-CZ2 3.98Å; F68-W305 HydrophobicContact CD1-CZ2 4.16Å; F68-W305 WeakPolarHBondContact O-CH2 3.19Å; F68-I306 WeakPolarHBondContact CA-O 3.23Å; F68-I306 PolarHBondContact N-O 3.42Å; F68-I307 HydrophobicContact CD1-CG1 4.16Å; F68-I307 HydrophobicContact CD1-CG2 4.27Å; F68-I307 HydrophobicContact CE1-CB 4.36Å; F68-I307 HydrophobicContact CE1-CD1 4.32Å; F68-I307 HydrophobicContact CE1-CG1 4.13Å; F68-I307 HydrophobicContact CE1-CG2 3.63Å; F68-I307 HydrophobicContact CZ-CG2 3.78Å
69R91.9Very high95.2Very high87 Ų8744.6 Ų44.633%0.32821%0.212SC..EExtended strand (participates in β ladder)trans-133.3150.3179.3-70-68.5-177.1-99.22110.7E66 Y71 I306E66-R69 HydrophobicContact CB-CG 3.76Å; R69-Y71 HydrophobicContact CB-CD2 4.4Å; R69-Y71 HydrophobicContact CB-CE2 3.7Å; R69-I306 PolarHBondContact N-O 3.44Å; R69-I306 PolarHBondContact O-N 2.95Å; R69-I306 VanDerWaalsContact O-N 3.09Å
70Y91.7Very high95.4Very high96 Ų9647 Ų4738%0.37623%0.23SC..EExtended strand (participates in β ladder)trans-80.7141.4163.2-71.1-78.2000110E39 Q42 G43 L304 W305E39-Y70 WeakPolarHBondContact OE2-CD1 3.29Å; E39-Y70 VanDerWaalsContact OE2-CD2 3.32Å; E39-Y70 WeakPolarHBondContact OE2-CD2 3.47Å; Q42-Y70 PolarHBondContact OE1-O 3.41Å; G43-Y70 PolarHBondContact N-O 3.1Å; Y70-L304 CarbonylContact C-O 3.54Å; Y70-L304 WeakPolarHBondContact CA-O 3.28Å; Y70-W305 HydrophobicContact CD1-CB 4.29Å; Y70-W305 AromaticContact CD1-CE3 3.9Å; Y70-W305 HydrophobicContact CD1-CE3 3.9Å; Y70-W305 AromaticContact CD2-CE3 3.73Å; Y70-W305 HydrophobicContact CD2-CE3 3.73Å; Y70-W305 AromaticContact CD2-CZ3 3.77Å; Y70-W305 HydrophobicContact CD2-CZ3 3.77Å; Y70-W305 HydrophobicContact CE1-CB 4.08Å; Y70-W305 HydrophobicContact CE1-CD2 4.44Å; Y70-W305 AromaticContact CE1-CE3 3.81Å; Y70-W305 HydrophobicContact CE1-CE3 3.81Å; Y70-W305 AromaticContact CE2-CE3 3.63Å; Y70-W305 HydrophobicContact CE2-CE3 3.63Å; Y70-W305 AromaticContact CE2-CZ3 3.67Å; Y70-W305 HydrophobicContact CE2-CZ3 3.67Å; Y70-W305 AromaticContact CG-CE3 3.86Å; Y70-W305 HydrophobicContact CG-CE3 3.86Å; Y70-W305 HydrophobicContact CG-CZ3 4.31Å; Y70-W305 AromaticContact CZ-CE3 3.69Å
71Y94.9Very high95.5Very high4 Ų445.3 Ų45.32%0.01622%0.222CC..EExtended strand (participates in β ladder)trans-12597.5173.1-68.8-91.1000107.4G43 K44 V45 P64 M65 E66 R69 L73 F302 D303 L304 I306G43-Y71 VanDerWaalsContact C-CE1 3.48Å; G43-Y71 WeakPolarHBondContact O-CE1 3.2Å; K44-Y71 WeakPolarHBondContact O-CE1 3.45Å; V45-Y71 HydrophobicContact CG1-CD1 3.58Å; V45-Y71 HydrophobicContact CG1-CE1 3.82Å; P64-Y71 HydrophobicContact CB-CD1 4Å; P64-Y71 HydrophobicContact CB-CD2 4.22Å; P64-Y71 HydrophobicContact CB-CE1 3.57Å; P64-Y71 HydrophobicContact CB-CE2 3.81Å; P64-Y71 HydrophobicContact CB-CG 4.3Å; P64-Y71 VanDerWaalsContact CB-CZ 3.46Å; P64-Y71 HydrophobicContact CG-CD1 4.41Å; P64-Y71 HydrophobicContact CG-CE1 4.43Å; M65-Y71 PolarHBondContact N-OH 3.02Å; E66-Y71 WeakPolarHBondContact CA-OH 3.48Å; E66-Y71 PolarHBondContact N-OH 3.45Å; E66-Y71 PolarHBondContact O-OH 3.3Å; R69-Y71 HydrophobicContact CB-CD2 4.4Å; R69-Y71 HydrophobicContact CB-CE2 3.7Å; Y71-L73 HydrophobicContact CD1-CD1 4.35Å; Y71-F302 CarbonylContact O-C 3.39Å; Y71-D303 WeakPolarHBondContact O-CA 3.05Å; Y71-L304 PolarHBondContact N-O 3Å; Y71-L304 PolarHBondContact O-N 3.07Å; Y71-I306 HydrophobicContact CD2-CB 3.92Å; Y71-I306 HydrophobicContact CD2-CD1 3.66Å; Y71-I306 HydrophobicContact CD2-CG1 3.85Å; Y71-I306 HydrophobicContact CE2-CB 3.86Å; Y71-I306 HydrophobicContact CE2-CD1 4.12Å; Y71-I306 HydrophobicContact CE2-CG1 4.27Å; Y71-I306 HydrophobicContact CE2-CG2 4.5Å; Y71-I306 HydrophobicContact CG-CD1 4.17Å
72Q96.3Very high95.4Very high0 Ų048.7 Ų48.70%024%0.24CC..EExtended strand (participates in β ladder)trans-110.288.1175.7-73.5153-6.900108.6S36 E39 F119 F302 D303S36-Q72 PolarHBondContact N-O 3.39Å; E39-Q72 PolarHBondContact OE2-NE2 2.97Å; Q72-F119 HydrophobicContact CB-CD1 4.14Å; Q72-F119 PolarHBondContact OE1-O 3.03Å; Q72-F302 CarbonylContact C-O 3.58Å; Q72-F302 VanDerWaalsContact CA-O 3.24Å; Q72-F302 WeakPolarHBondContact CA-O 3.35Å; Q72-D303 HydrophobicContact CG-CB 4.22Å; Q72-D303 VanDerWaalsContact CG-OD1 3.25Å; Q72-D303 WeakPolarHBondContact CG-OD1 3.5Å; Q72-D303 PolarHBondContact NE2-OD1 3.29Å; Q72-D303 VanDerWaalsContact NE2-OD1 3.1Å
73L97.2Very high95.1Very high4 Ų448.6 Ų48.62%0.02124%0.24CC..EExtended strand (participates in β ladder)trans-116.5137.2177.6-77.597.1000110W33 V34 Q35 V45 L62 Y71 G301 F302W33-L73 HydrophobicContact CE3-CB 4.04Å; W33-L73 HydrophobicContact CZ3-CB 4.44Å; V34-L73 WeakPolarHBondContact O-CA 3.48Å; Q35-L73 HydrophobicContact CB-CG 4.26Å; Q35-L73 HydrophobicContact CG-CD1 4.37Å; Q35-L73 HydrophobicContact CG-CG 4.25Å; V45-L73 HydrophobicContact CB-CD2 4.41Å; V45-L73 HydrophobicContact CG1-CD1 3.61Å; V45-L73 HydrophobicContact CG1-CD2 4.12Å; V45-L73 HydrophobicContact CG2-CD2 3.71Å; L62-L73 HydrophobicContact CD1-CD2 4.36Å; L62-L73 HydrophobicContact CD2-CD2 4.36Å; Y71-L73 HydrophobicContact CD1-CD1 4.35Å; L73-G301 CarbonylContact O-C 3.58Å; L73-G301 WeakPolarHBondContact O-CA 3.46Å; L73-F302 PolarHBondContact N-O 3.48Å; L73-F302 PolarHBondContact O-N 3.01Å
74S98.3Very high94.8Very high0 Ų052 Ų520%026%0.258CS..EExtended strand (participates in β ladder)trans-148.2154.6179.758.10000112V34 L116 V300V34-S74 PolarHBondContact N-O 3.47Å; V34-S74 PolarHBondContact O-N 2.85Å; S74-L116 WeakPolarHBondContact OG-CB 3.5Å; S74-L116 WeakPolarHBondContact OG-CD2 3.4Å; S74-V300 CarbonylContact C-O 3.53Å; S74-V300 WeakPolarHBondContact CA-O 3.34Å; S74-V300 VanDerWaalsContact CB-O 3.28Å; S74-V300 WeakPolarHBondContact CB-O 3.41Å
75R98.1Very high94.6Very high19 Ų1954.5 Ų54.57%0.07228%0.284CS..EExtended strand (participates in β ladder)trans-138.6144.2-179.3162.1171.3-173.4-157.8-5.4109.3L19 E21 R32 W33 D78 A299 V300L19-R75 VanDerWaalsContact CD1-CZ 3.43Å; E21-R75 IonicContact OE2-CZ 3.08Å; E21-R75 IonicContact OE2-NH1 3.5Å; E21-R75 PolarHBondContact OE2-NH1 3.4Å; R32-R75 HydrophobicContact CB-CG 4.42Å; R32-R75 WeakPolarHBondContact O-CB 3.39Å; R32-R75 WeakPolarHBondContact O-CG 3.39Å; W33-R75 HydrophobicContact CD2-CB 3.84Å; W33-R75 HydrophobicContact CE3-CB 4.04Å; W33-R75 HydrophobicContact CG-CB 4.21Å; W33-R75 HydrophobicContact CZ2-CB 4.34Å; W33-R75 HydrophobicContact CZ3-CB 4.41Å; R75-D78 IonicContact CZ-OD1 3.38Å; R75-D78 IonicContact NH2-OD1 3.52Å; R75-D78 PolarHBondContact NH2-OD1 3.49Å; R75-D78 IonicContact NH2-OD2 2.82Å; R75-A299 CarbonylContact O-C 3.58Å; R75-A299 WeakPolarHBondContact O-CA 3.4Å; R75-A299 VanDerWaalsContact O-CB 3.22Å; R75-A299 WeakPolarHBondContact O-CB 3.35Å; R75-V300 HydrophobicContact CB-CG1 4.48Å; R75-V300 PolarHBondContact N-O 2.91Å; R75-V300 PolarHBondContact O-N 2.97Å
76K98.5Very high94.4Very high143 Ų14354.4 Ų54.462%0.62228%0.282SS*.EExtended strand (participates in β ladder)trans-69.7141.8168.9-66-175.2-178.9173.20110.5L116 G298K76-L116 HydrophobicContact CG-CD1 3.83Å; K76-G298 WeakPolarHBondContact CA-O 3.22Å
77L98.2Very high94.4Very high9 Ų952.6 Ų52.65%0.04728%0.275CS..EExtended strand (participates in β ladder)trans-64.2152.6167.1-56.4-170.5000109.7L19 V79 F81 I297 G298 V300 I318L19-L77 HydrophobicContact CB-CD2 3.94Å; L19-L77 HydrophobicContact CD2-CD2 3.92Å; L19-L77 HydrophobicContact CG-CD2 4.47Å; L77-V79 PolarHBondContact O-N 3.26Å; L77-F81 HydrophobicContact CD1-CD1 3.88Å; L77-F81 HydrophobicContact CD1-CE1 3.6Å; L77-I297 HydrophobicContact CD1-CG2 3.77Å; L77-G298 PolarHBondContact N-O 2.92Å; L77-V300 HydrophobicContact CD2-CB 4.24Å; L77-V300 HydrophobicContact CD2-CG1 4.36Å; L77-I318 HydrophobicContact CD2-CD1 3.56Å
78D96.8Very high94.6Very high94 Ų9450 Ų5050%0.50326%0.257SS..EExtended strand (participates in β ladder)trans-66.5-35.9176.7-61.2-36.8000110.4Y18 R75Y18-D78 PolarHBondContact O-N 2.86Å; R75-D78 IonicContact CZ-OD1 3.38Å; R75-D78 IonicContact NH2-OD1 3.52Å; R75-D78 PolarHBondContact NH2-OD1 3.49Å; R75-D78 IonicContact NH2-OD2 2.82Å
79V94.4Very high94.9Very high74 Ų7444.3 Ų44.345%0.44823%0.232SC..EExtended strand (participates in β ladder)trans-134.2112.3174.1-175.30000109.6Y18 L77Y18-V79 HydrophobicContact CD1-CB 4.31Å; Y18-V79 WeakPolarHBondContact CD1-O 3.5Å; L77-V79 PolarHBondContact O-N 3.26Å
80P95.9Very high95.2Very high77 Ų7740.2 Ų40.250%0.522%0.217SC..EExtended strand (participates in β ladder)trans-62144.4169.6-21.532.9000111.4I297P80-I297 CarbonylContact C-O 3.53Å; P80-I297 VanDerWaalsContact CA-O 3.25Å; P80-I297 WeakPolarHBondContact CA-O 3.38Å
81F96.1Very high95.5Very high15 Ų1535.6 Ų35.67%0.06620%0.199CC..EExtended strand (participates in β ladder)trans-149.1175.8-175.674.4-71.3000112.4Y18 L77 T83 L88 S296 I297 I318Y18-F81 HydrophobicContact CD1-CB 3.67Å; Y18-F81 AromaticContact CD1-CD1 3.57Å; Y18-F81 HydrophobicContact CD1-CD1 3.57Å; Y18-F81 HydrophobicContact CD1-CD2 4.29Å; Y18-F81 HydrophobicContact CD1-CE1 4.26Å; Y18-F81 AromaticContact CD1-CG 3.59Å; Y18-F81 HydrophobicContact CD1-CG 3.59Å; Y18-F81 AromaticContact CD2-CD1 3.84Å; Y18-F81 HydrophobicContact CD2-CD1 3.84Å; Y18-F81 AromaticContact CD2-CD2 3.98Å; Y18-F81 HydrophobicContact CD2-CD2 3.98Å; Y18-F81 AromaticContact CD2-CE1 3.72Å; Y18-F81 HydrophobicContact CD2-CE1 3.72Å; Y18-F81 AromaticContact CD2-CE2 3.86Å; Y18-F81 HydrophobicContact CD2-CE2 3.86Å; Y18-F81 AromaticContact CD2-CG 3.97Å; Y18-F81 HydrophobicContact CD2-CG 3.97Å; Y18-F81 AromaticContact CD2-CZ 3.72Å; Y18-F81 HydrophobicContact CD2-CZ 3.72Å; Y18-F81 HydrophobicContact CE1-CB 3.32Å; Y18-F81 AromaticContact CE1-CD1 3.98Å; Y18-F81 HydrophobicContact CE1-CD1 3.98Å; Y18-F81 AromaticContact CE1-CD2 3.9Å; Y18-F81 HydrophobicContact CE1-CD2 3.9Å; Y18-F81 AromaticContact CE1-CG 3.48Å; Y18-F81 HydrophobicContact CE1-CG 3.48Å; Y18-F81 VanDerWaalsContact CE1-CG 3.48Å; Y18-F81 HydrophobicContact CE2-CD1 4.22Å; Y18-F81 AromaticContact CE2-CD2 3.55Å; Y18-F81 HydrophobicContact CE2-CD2 3.55Å; Y18-F81 HydrophobicContact CE2-CE1 4.29Å; Y18-F81 AromaticContact CE2-CE2 3.63Å; Y18-F81 HydrophobicContact CE2-CE2 3.63Å; Y18-F81 AromaticContact CE2-CG 3.87Å; Y18-F81 HydrophobicContact CE2-CG 3.87Å; Y18-F81 HydrophobicContact CE2-CZ 4.01Å; Y18-F81 HydrophobicContact CG-CB 4.42Å; Y18-F81 AromaticContact CG-CD1 3.5Å; Y18-F81 HydrophobicContact CG-CD1 3.5Å; Y18-F81 VanDerWaalsContact CG-CD1 3.5Å; Y18-F81 HydrophobicContact CG-CD2 4.33Å; Y18-F81 AromaticContact CG-CE1 3.7Å; Y18-F81 HydrophobicContact CG-CE1 3.7Å; Y18-F81 HydrophobicContact CG-CE2 4.5Å; Y18-F81 AromaticContact CG-CG 3.85Å; Y18-F81 HydrophobicContact CG-CG 3.85Å; Y18-F81 HydrophobicContact CG-CZ 4.2Å; Y18-F81 AromaticContact CZ-CD2 3.5Å; Y18-F81 AromaticContact CZ-CG 3.63Å; L77-F81 HydrophobicContact CD1-CD1 3.88Å; L77-F81 HydrophobicContact CD1-CE1 3.6Å; F81-T83 HydrophobicContact CE2-CG2 4.48Å; F81-L88 HydrophobicContact CE2-CD1 3.96Å; F81-L88 HydrophobicContact CZ-CD1 3.58Å; F81-S296 CarbonylContact O-C 3.53Å; F81-S296 WeakPolarHBondContact O-CA 3.4Å; F81-I297 HydrophobicContact CD1-CB 4.3Å; F81-I297 HydrophobicContact CE1-CB 4.01Å; F81-I297 HydrophobicContact CE1-CD1 4.19Å; F81-I297 HydrophobicContact CE1-CG2 4.14Å; F81-I297 HydrophobicContact CE2-CD1 4.18Å; F81-I297 HydrophobicContact CZ-CB 4.49Å; F81-I297 HydrophobicContact CZ-CD1 3.8Å; F81-I297 PolarHBondContact N-O 3.38Å; F81-I297 PolarHBondContact O-N 2.67Å; F81-I318 HydrophobicContact CE1-CG2 3.77Å; F81-I318 HydrophobicContact CZ-CG2 3.69Å
82N93.9Very high95.6Very high72 Ų7235.4 Ų35.439%0.38520%0.198SC..  trans-129.5167.8166.767.456.3000109.1L84N82-L84 WeakPolarHBondContact OD1-CB 3.33Å; N82-L84 PolarHBondContact OD1-N 2.62Å; N82-L84 VanDerWaalsContact OD1-N 3.09Å
83T91.9Very high95.6Very high3 Ų335.6 Ų35.62%0.01820%0.199CC..  trans-92.1-0.4-174580000113.7F81 G85 K86 L88 Q291 H294 I297F81-T83 HydrophobicContact CE2-CG2 4.48Å; T83-G85 PolarHBondContact O-N 2.95Å; T83-K86 PolarHBondContact O-N 2.97Å; T83-K86 VanDerWaalsContact O-N 3.16Å; T83-L88 HydrophobicContact CG2-CB 3.91Å; T83-L88 HydrophobicContact CG2-CD2 4.26Å; T83-Q291 PolarHBondContact O-NE2 3.04Å; T83-H294 HydrophobicContact CG2-CB 4.01Å; T83-H294 PolarHBondContact OG1-CD2 3.07Å; T83-H294 VanDerWaalsContact OG1-CD2 3.31Å; T83-H294 PolarHBondContact OG1-N 3.25Å; T83-I297 HydrophobicContact CG2-CD1 4.11Å
84L91Very high95.5Very high80 Ų8035.6 Ų35.642%0.41920%0.199SC..THydrogen-bonded Turntrans-65.6127.3-174.8-67.1175.7000111N82 K86 Q291 D293N82-L84 WeakPolarHBondContact OD1-CB 3.33Å; N82-L84 PolarHBondContact OD1-N 2.62Å; N82-L84 VanDerWaalsContact OD1-N 3.09Å; L84-K86 PolarHBondContact O-N 3.17Å; L84-K86 VanDerWaalsContact O-N 3.15Å; L84-Q291 HydrophobicContact CD2-CG 4.46Å; L84-D293 HydrophobicContact CD2-CB 3.97Å; L84-D293 HydrophobicContact CG-CB 4.43Å
85G90Very high95.3Very high57 Ų5735.9 Ų35.959%0.58820%0.201SC*.THydrogen-bonded Turntrans69.1-1.1-176.700000115.8T83T83-G85 PolarHBondContact O-N 2.95Å
86K91.7Very high95.1Very high77 Ų7735.5 Ų35.534%0.33520%0.2SC..SBendtrans-126.3155.7-172.1-66.4175.7165.8-135.30112Y18 T83 L84 D320Y18-K86 PolarHBondContact OH-NZ 3.36Å; T83-K86 PolarHBondContact O-N 2.97Å; T83-K86 VanDerWaalsContact O-N 3.16Å; L84-K86 PolarHBondContact O-N 3.17Å; L84-K86 VanDerWaalsContact O-N 3.15Å; K86-D320 HydrophobicContact CB-CB 4.19Å; K86-D320 WeakPolarHBondContact CD-OD2 3.31Å; K86-D320 IonicContact NZ-OD2 3.29Å; K86-D320 PolarHBondContact NZ-OD2 3.08Å
87S93.2Very high94.8Very high19 Ų1929.2 Ų29.213%0.13317%0.173CC..  trans-75148.4167-55.90000109I173 H174 D320S87-I173 CarbonylContact C-O 3.52Å; S87-I173 VanDerWaalsContact CA-O 3.22Å; S87-I173 WeakPolarHBondContact CA-O 3.41Å; S87-H174 PolarHBondContact OG-ND1 2.82Å; S87-D320 VanDerWaalsContact O-CA 3.26Å; S87-D320 WeakPolarHBondContact O-CA 3.4Å; S87-D320 VanDerWaalsContact O-CB 3.23Å; S87-D320 WeakPolarHBondContact O-CB 3.47Å
88L95.9Very high94.3Very high1 Ų134.4 Ų34.41%0.00519%0.192CC..EExtended strand (participates in β ladder)trans-101.5126160.516864.1000107.2F81 T83 L109 I127 I172 I173 I297 I318F81-L88 HydrophobicContact CE2-CD1 3.96Å; F81-L88 HydrophobicContact CZ-CD1 3.58Å; T83-L88 HydrophobicContact CG2-CB 3.91Å; T83-L88 HydrophobicContact CG2-CD2 4.26Å; L88-L109 HydrophobicContact CD1-CD1 4.11Å; L88-L109 HydrophobicContact CD2-CD1 3.9Å; L88-I127 HydrophobicContact CD2-CD1 3.33Å; L88-I172 CarbonylContact O-C 3.13Å; L88-I172 VanDerWaalsContact O-CA 3.32Å; L88-I172 WeakPolarHBondContact O-CA 3.38Å; L88-I173 HydrophobicContact CB-CB 4.37Å; L88-I173 HydrophobicContact CD2-CD1 4.28Å; L88-I173 PolarHBondContact N-O 2.81Å; L88-I173 PolarHBondContact O-N 2.92Å; L88-I297 HydrophobicContact CD1-CD1 4.39Å; L88-I297 HydrophobicContact CD2-CD1 4.43Å; L88-I318 HydrophobicContact CD1-CG2 4.27Å
89V96.9Very high93.8Very high0 Ų035.1 Ų35.10%020%0.196CC..EExtended strand (participates in β ladder)trans-120.2123.3167.3-169.30000108.2T170 L171 I172 I318 T319 T322 V325V89-T170 HydrophobicContact CG1-CG2 3.96Å; V89-L171 WeakPolarHBondContact CA-O 3.38Å; V89-I172 HydrophobicContact CG1-CG1 3.97Å; V89-I172 HydrophobicContact CG2-CG1 4.29Å; V89-I172 HydrophobicContact CG2-CG2 4.37Å; V89-I318 VanDerWaalsContact O-CA 3.3Å; V89-I318 WeakPolarHBondContact O-CA 3.35Å; V89-T319 HydrophobicContact CB-CG2 3.89Å; V89-T319 WeakPolarHBondContact CB-O 3.22Å; V89-T319 HydrophobicContact CG1-CG2 4.44Å; V89-T319 HydrophobicContact CG2-CG2 4.35Å; V89-T319 PolarHBondContact N-O 3.24Å; V89-T319 PolarHBondContact O-N 3.42Å; V89-T322 HydrophobicContact CG2-CG2 3.81Å; V89-V325 HydrophobicContact CB-CG2 4.14Å; V89-V325 HydrophobicContact CG1-CB 4.11Å; V89-V325 HydrophobicContact CG1-CG1 4.2Å; V89-V325 HydrophobicContact CG1-CG2 3.4Å
90L98.1Very high93.4Very high0 Ų031.8 Ų31.80%018%0.175CC..EExtended strand (participates in β ladder)trans-120.8118.4172.816663.3000107.7I107 L109 F129 T170 L171 I318L90-I107 HydrophobicContact CD1-CG2 4.05Å; L90-I107 HydrophobicContact CD2-CG2 3.74Å; L90-I107 HydrophobicContact CG-CG2 4.27Å; L90-L109 HydrophobicContact CD1-CD2 4.24Å; L90-L109 HydrophobicContact CD2-CD1 4.13Å; L90-L109 HydrophobicContact CD2-CD2 4.3Å; L90-L109 HydrophobicContact CD2-CG 4.05Å; L90-F129 HydrophobicContact CD2-CB 4.02Å; L90-F129 HydrophobicContact CD2-CD1 4.03Å; L90-F129 HydrophobicContact CD2-CG 4.47Å; L90-F129 HydrophobicContact CG-CD1 4.31Å; L90-T170 CarbonylContact O-C 3.55Å; L90-T170 WeakPolarHBondContact O-CA 3.35Å; L90-L171 PolarHBondContact N-O 2.63Å; L90-L171 PolarHBondContact O-N 2.76Å; L90-I318 HydrophobicContact CD1-CD1 4.19Å; L90-I318 HydrophobicContact CD1-CG1 3.82Å
91Q97.7Very high92.9Very high0 Ų033.6 Ų33.60%018%0.181CC..EExtended strand (participates in β ladder)trans-128.5147.6175.1-178161.1-76.700110.7F168 Y169 T170 I316 L317 V325 D329Q91-F168 HydrophobicContact CG-CD1 3.86Å; Q91-Y169 WeakPolarHBondContact CA-O 3.43Å; Q91-T170 HydrophobicContact CB-CG2 4.16Å; Q91-T170 PolarHBondContact OE1-OG1 2.92Å; Q91-I316 CarbonylContact O-C 3.53Å; Q91-I316 WeakPolarHBondContact O-CA 3.41Å; Q91-L317 HydrophobicContact CB-CB 4.33Å; Q91-L317 PolarHBondContact N-O 3.46Å; Q91-L317 PolarHBondContact O-N 2.84Å; Q91-V325 HydrophobicContact CB-CG1 4.2Å; Q91-V325 HydrophobicContact CG-CG1 4.42Å; Q91-D329 PolarHBondContact NE2-OD1 3.25Å; Q91-D329 PolarHBondContact OE1-OD1 2.77Å; Q91-D329 PolarHBondContact OE1-OD2 2.98Å
92Y97.5Very high92.5Very high0 Ų034 Ų340%019%0.186CC..EExtended strand (participates in β ladder)trans-160.7161.4163.967.2-66.6000109.3V94 A105 Y106 I107 F129 G130 P131 Y169 F302 F313 N315Y92-V94 HydrophobicContact CD2-CG2 3.72Å; Y92-V94 HydrophobicContact CE2-CG2 3.23Å; Y92-A105 WeakPolarHBondContact CE2-O 3.26Å; Y92-A105 PolarHBondContact OH-O 3.34Å; Y92-Y106 WeakPolarHBondContact OH-CA 3.27Å; Y92-I107 HydrophobicContact CD1-CG2 3.94Å; Y92-I107 HydrophobicContact CE1-CB 4.14Å; Y92-I107 HydrophobicContact CE1-CG2 3.57Å; Y92-F129 HydrophobicContact CE1-CD1 4.11Å; Y92-F129 HydrophobicContact CE1-CE1 4.37Å; Y92-F129 PolarHBondContact OH-O 2.88Å; Y92-G130 WeakPolarHBondContact OH-CA 3.48Å; Y92-P131 WeakPolarHBondContact OH-CD 3.2Å; Y92-Y169 PolarHBondContact N-O 2.99Å; Y92-Y169 PolarHBondContact O-N 3.22Å; Y92-F302 HydrophobicContact CD2-CE1 4.48Å; Y92-F302 HydrophobicContact CE2-CE1 4.31Å; Y92-F313 HydrophobicContact CD2-CD1 4.35Å; Y92-F313 HydrophobicContact CE2-CD1 4.16Å; Y92-N315 WeakPolarHBondContact CA-O 3.43Å
93S95.3Very high92.1Very high3 Ų330.8 Ų30.82%0.02117%0.168CC..EExtended strand (participates in β ladder)trans-102.1141.9174.158.90000111.6H167 F313 D314 N315S93-H167 CarbonylContact C-O 3.46Å; S93-H167 VanDerWaalsContact CA-O 3.25Å; S93-H167 WeakPolarHBondContact CA-O 3.37Å; S93-F313 WeakPolarHBondContact O-CA 3.43Å; S93-D314 PolarHBondContact N-O 3.12Å; S93-D314 PolarHBondContact O-N 3.02Å; S93-D314 VanDerWaalsContact OG-C 3.25Å; S93-D314 WeakPolarHBondContact OG-CB 3.26Å; S93-D314 PolarHBondContact OG-O 3.05Å; S93-D314 VanDerWaalsContact OG-O 3.06Å; S93-N315 PolarHBondContact OG-ND2 2.76Å
94V95.6Very high91.9Very high4 Ų430.9 Ų30.92%0.02417%0.171CC..EExtended strand (participates in β ladder)trans-123.7131.8172.2-177.90000108.1Y92 A105 P131 H167 Y169 I311 V312 F313Y92-V94 HydrophobicContact CD2-CG2 3.72Å; Y92-V94 HydrophobicContact CE2-CG2 3.23Å; V94-A105 HydrophobicContact CG1-CB 3.84Å; V94-A105 HydrophobicContact CG2-CB 4.4Å; V94-P131 HydrophobicContact CB-CG 4.31Å; V94-P131 HydrophobicContact CG1-CG 4.32Å; V94-P131 HydrophobicContact CG2-CG 4Å; V94-H167 PolarHBondContact N-O 3.35Å; V94-H167 PolarHBondContact O-N 2.91Å; V94-Y169 HydrophobicContact CB-CD2 4.34Å; V94-Y169 HydrophobicContact CB-CE2 4.13Å; V94-Y169 HydrophobicContact CG2-CD2 4.19Å; V94-Y169 HydrophobicContact CG2-CE2 4.38Å; V94-I311 HydrophobicContact CG1-CG2 3.86Å; V94-V312 WeakPolarHBondContact CA-O 3.39Å; V94-F313 HydrophobicContact CG2-CD1 4.09Å; V94-F313 HydrophobicContact CG2-CE1 4.22Å
95K94.8Very high92.1Very high7 Ų727.3 Ų27.33%0.0315%0.152CC..EExtended strand (participates in β ladder)trans-121.1125.5170.7179.3-175.9-176152.60110F52 I311 V312 E340F52-K95 PolarHBondContact O-NZ 3.19Å; K95-I311 CarbonylContact O-C 3.57Å; K95-I311 VanDerWaalsContact O-CA 3.25Å; K95-I311 WeakPolarHBondContact O-CA 3.31Å; K95-V312 HydrophobicContact CB-CB 4.11Å; K95-V312 HydrophobicContact CB-CG2 4.41Å; K95-V312 HydrophobicContact CD-CG2 4.3Å; K95-V312 PolarHBondContact N-O 2.79Å; K95-V312 PolarHBondContact O-N 3.07Å; K95-E340 WeakPolarHBondContact CE-OE1 3.42Å; K95-E340 IonicContact NZ-OE1 3.27Å; K95-E340 PolarHBondContact NZ-OE1 2.79Å
96N94.1Very high92.5Very high11 Ų1126.5 Ų26.56%0.05913%0.132CC..EExtended strand (participates in β ladder)trans-91.5110.8168.9-60.5-33.8000108R98 I100 E164 E310N96-R98 PolarHBondContact O-N 3.43Å; N96-R98 VanDerWaalsContact O-N 3.09Å; N96-I100 HydrophobicContact CB-CD1 3.76Å; N96-I100 HydrophobicContact CB-CG1 3.95Å; N96-I100 WeakPolarHBondContact OD1-CD1 3.43Å; N96-E164 CarbonylContact O-C 3.42Å; N96-E164 WeakPolarHBondContact O-CA 3.08Å; N96-E164 WeakPolarHBondContact O-CB 3.47Å; N96-E310 CarbonylContact C-O 3.5Å
97Q91.1Very high92.8Very high11 Ų1122.9 Ų22.95%0.05112%0.116CC..SBendtrans-68.7-15.9-176.1-54.8-177.155.900113.1G50 E310 V312G50-Q97 VanDerWaalsContact C-OE1 3.3Å; Q97-E310 HydrophobicContact CB-CB 4.17Å; Q97-E310 PolarHBondContact N-O 2.81Å; Q97-V312 HydrophobicContact CG-CG2 3.93Å
98R89.3Confident93Very high117 Ų11722.1 Ų22.144%0.44211%0.11SC..SBendtrans-146.4166.3177.2-62-175.3-172179.54.5109.6D51 N96 I100 E164 E310D51-R98 IonicContact OD2-NH2 2.62Å; N96-R98 PolarHBondContact O-N 3.43Å; N96-R98 VanDerWaalsContact O-N 3.09Å; R98-I100 VanDerWaalsContact O-CG1 3.31Å; R98-I100 WeakPolarHBondContact O-CG1 3.37Å; R98-I100 PolarHBondContact O-N 2.89Å; R98-E164 WeakPolarHBondContact CA-OE1 3.18Å; R98-E310 WeakPolarHBondContact CD-OE2 3.46Å; R98-E310 WeakPolarHBondContact CG-OE2 3.3Å; R98-E310 IonicContact CZ-OE1 2.74Å; R98-E310 IonicContact CZ-OE2 2.93Å; R98-E310 IonicContact NE-OE1 3.33Å; R98-E310 PolarHBondContact NE-OE1 3.18Å; R98-E310 IonicContact NE-OE2 2.9Å; R98-E310 PolarHBondContact NE-OE2 2.85Å; R98-E310 VanDerWaalsContact NE-OE2 3.1Å; R98-E310 IonicContact NH1-OE1 2.75Å; R98-E310 PolarHBondContact NH1-OE1 2.88Å; R98-E310 IonicContact NH2-OE1 3.88Å; R98-E310 IonicContact NH2-OE2 2.82Å
99N86.3Confident93.2Very high110 Ų11022.1 Ų22.159%0.58811%0.11SC*.  trans-54.4110.4166.2-70.6-20.7000111.5E164N99-E164 PolarHBondContact N-OE1 3.25Å
100I85.7Confident93.2Very high3 Ų322.1 Ų22.12%0.01511%0.11CC..  trans-85.7133.6-179.9-60.3-170.7000109.9N96 R98 A103 I133 R139 I311N96-I100 HydrophobicContact CB-CD1 3.76Å; N96-I100 HydrophobicContact CB-CG1 3.95Å; N96-I100 WeakPolarHBondContact OD1-CD1 3.43Å; R98-I100 VanDerWaalsContact O-CG1 3.31Å; R98-I100 WeakPolarHBondContact O-CG1 3.37Å; R98-I100 PolarHBondContact O-N 2.89Å; I100-A103 HydrophobicContact CG2-CB 3.73Å; I100-I133 HydrophobicContact CG2-CG2 4.49Å; I100-R139 PolarHBondContact O-NH2 2.94Å; I100-I311 HydrophobicContact CD1-CD1 3.7Å; I100-I311 HydrophobicContact CD1-CG1 3.24Å
101N84.5Confident93.2Very high115 Ų11523.5 Ų23.562%0.61512%0.119SC*.SBendtrans-85.4-48.1173.7-73.3-15000111.5C134 G135N101-C134 CarbonylContact O-C 3.43Å; N101-G135 PolarHBondContact O-N 3.1Å
102C87.6Confident93.1Very high25 Ų2525.7 Ų25.717%0.16914%0.137CC..EExtended strand (participates in β ladder)trans-153.7116175.9-176.20000111.7I133 C134 I307C102-I133 CarbonylContact C-O 3.49Å; C102-I133 WeakPolarHBondContact CA-O 3.49Å; C102-C134 HydrophobicContact CB-CB 3.92Å; C102-C134 WeakPolarHBondContact CB-SG 3.43Å; C102-C134 WeakPolarHBondContact SG-CB 3.41Å; C102-C134 CovalentContact SG-SG 2.06Å; C102-C134 PolarHBondContact SG-SG 3.38Å; C102-I307 HydrophobicContact CB-CD1 4.08Å
103A85.4Confident93Very high3 Ų329.7 Ų29.73%0.02518%0.178CC..EExtended strand (participates in β ladder)trans-160.2133.3169.200000110I100 I133 I311I100-A103 HydrophobicContact CG2-CB 3.73Å; A103-I133 CarbonylContact C-O 3.56Å; A103-I133 PolarHBondContact N-O 3.12Å; A103-I133 PolarHBondContact O-N 3.45Å; A103-I133 VanDerWaalsContact O-N 3.09Å; A103-I133 VanDerWaalsContact O-O 3.14Å; A103-I311 HydrophobicContact CB-CD1 3.45Å; A103-I311 VanDerWaalsContact CB-CD1 3.45Å
104G88.8Confident93.1Very high6 Ų630.8 Ų30.86%0.06219%0.185CC..EExtended strand (participates in β ladder)trans-74.5138.8161.100000109.2L304G104-L304 WeakPolarHBondContact O-CD2 3.47Å
105A95.4Very high93.2Very high4 Ų435.1 Ų35.13%0.03321%0.208CC..  trans-134.537.4175.600000110.4Y92 V94 P131 F313Y92-A105 WeakPolarHBondContact CE2-O 3.26Å; Y92-A105 PolarHBondContact OH-O 3.34Å; V94-A105 HydrophobicContact CG1-CB 3.84Å; V94-A105 HydrophobicContact CG2-CB 4.4Å; A105-P131 CarbonylContact C-O 3.56Å; A105-P131 WeakPolarHBondContact CA-O 3.47Å; A105-P131 HydrophobicContact CB-CG 3.93Å; A105-P131 PolarHBondContact N-O 3.34Å; A105-P131 WeakPolarHBondContact O-CD 3.28Å; A105-F313 HydrophobicContact CB-CE1 3.62Å; A105-F313 HydrophobicContact CB-CZ 3.81Å
106Y96.8Very high93.3Very high41 Ų4135.4 Ų35.416%0.16121%0.21CC..  trans-95.2153.3179.149.9-101.6000113.1Y92 M128 F129 P131 D132 D303 L304Y92-Y106 WeakPolarHBondContact OH-CA 3.27Å; Y106-M128 HydrophobicContact CD2-CE 4.15Å; Y106-M128 HydrophobicContact CD2-CG 3.65Å; Y106-M128 HydrophobicContact CD2-SD 3.76Å; Y106-M128 HydrophobicContact CE2-CE 3.85Å; Y106-M128 HydrophobicContact CE2-CG 4.32Å; Y106-M128 HydrophobicContact CE2-SD 3.92Å; Y106-M128 HydrophobicContact CG-CG 4.01Å; Y106-M128 HydrophobicContact CG-SD 4.1Å; Y106-F129 WeakPolarHBondContact CA-O 3.22Å; Y106-P131 PolarHBondContact N-O 2.84Å; Y106-D132 HydrophobicContact CD1-CB 4.22Å; Y106-D303 WeakPolarHBondContact CE2-O 3.46Å; Y106-L304 HydrophobicContact CD2-CD2 3.96Å; Y106-L304 HydrophobicContact CE1-CD2 4.43Å; Y106-L304 HydrophobicContact CE2-CD2 3.82Å; Y106-L304 HydrophobicContact CG-CD2 4.33Å; Y106-L304 WeakPolarHBondContact O-CD2 3.36Å
107I98.6Very high93.4Very high0 Ų036.6 Ų36.60%022%0.219CC..EExtended strand (participates in β ladder)trans-111.2147.3178.7-156.5171.5000110.4L90 Y92 M128 F129 V300 F302 I316L90-I107 HydrophobicContact CD1-CG2 4.05Å; L90-I107 HydrophobicContact CD2-CG2 3.74Å; L90-I107 HydrophobicContact CG-CG2 4.27Å; Y92-I107 HydrophobicContact CD1-CG2 3.94Å; Y92-I107 HydrophobicContact CE1-CB 4.14Å; Y92-I107 HydrophobicContact CE1-CG2 3.57Å; I107-M128 CarbonylContact O-C 3.56Å; I107-M128 WeakPolarHBondContact O-CA 3.37Å; I107-F129 PolarHBondContact N-O 3.3Å; I107-F129 PolarHBondContact O-N 2.82Å; I107-V300 HydrophobicContact CD1-CG2 3.23Å; I107-V300 HydrophobicContact CG1-CG2 3.38Å; I107-F302 HydrophobicContact CB-CD1 4.27Å; I107-F302 HydrophobicContact CB-CE1 3.82Å; I107-F302 HydrophobicContact CB-CZ 4.49Å; I107-F302 HydrophobicContact CD1-CE1 3.85Å; I107-F302 HydrophobicContact CD1-CE2 4.35Å; I107-F302 HydrophobicContact CD1-CZ 3.65Å; I107-F302 HydrophobicContact CG1-CD1 4.09Å; I107-F302 HydrophobicContact CG1-CE1 3.66Å; I107-F302 HydrophobicContact CG1-CZ 3.94Å; I107-I316 HydrophobicContact CD1-CD1 4.34Å; I107-I316 HydrophobicContact CD1-CG1 4.4Å; I107-I316 HydrophobicContact CD1-CG2 3.83Å
108K98.5Very high93.7Very high4 Ų440.1 Ų40.12%0.01724%0.236CC..EExtended strand (participates in β ladder)trans-112.1133.7177.4-69.5177174.5175.60110.6L110 F119 Y125 I127 M128 V300 G301 D303K108-L110 HydrophobicContact CB-CD2 3.98Å; K108-F119 HydrophobicContact CD-CE2 4.35Å; K108-F119 HydrophobicContact CD-CZ 4.19Å; K108-Y125 HydrophobicContact CD-CD1 4.07Å; K108-Y125 HydrophobicContact CD-CG 4.26Å; K108-Y125 HydrophobicContact CG-CG 4.37Å; K108-I127 CarbonylContact C-O 3.57Å; K108-I127 WeakPolarHBondContact CA-O 3.38Å; K108-M128 HydrophobicContact CD-CE 4.42Å; K108-M128 HydrophobicContact CG-CB 4.21Å; K108-M128 HydrophobicContact CG-CE 4.43Å; K108-M128 HydrophobicContact CG-CG 4.22Å; K108-V300 CarbonylContact O-C 3.59Å; K108-V300 VanDerWaalsContact O-CA 3.29Å; K108-V300 WeakPolarHBondContact O-CA 3.26Å; K108-V300 WeakPolarHBondContact O-CG2 3.49Å; K108-G301 PolarHBondContact N-O 3.09Å; K108-G301 PolarHBondContact O-N 3.19Å; K108-D303 HydrophobicContact CD-CB 4.37Å; K108-D303 IonicContact NZ-OD2 2.64Å; K108-D303 PolarHBondContact NZ-OD2 3.07Å
109L98.5Very high94Very high0 Ų034.6 Ų34.60%022%0.215CC..EExtended strand (participates in β ladder)trans-90.5122.2164.9-64.5-176.1000109.2L88 L90 Y125 H126 I127 I297 V300 I318L88-L109 HydrophobicContact CD1-CD1 4.11Å; L88-L109 HydrophobicContact CD2-CD1 3.9Å; L90-L109 HydrophobicContact CD1-CD2 4.24Å; L90-L109 HydrophobicContact CD2-CD1 4.13Å; L90-L109 HydrophobicContact CD2-CD2 4.3Å; L90-L109 HydrophobicContact CD2-CG 4.05Å; L109-Y125 WeakPolarHBondContact O-CA 2.97Å; L109-Y125 WeakPolarHBondContact O-CB 3.12Å; L109-H126 PolarHBondContact O-N 3.5Å; L109-I127 HydrophobicContact CB-CB 4.3Å; L109-I127 HydrophobicContact CD1-CB 4.23Å; L109-I127 HydrophobicContact CD1-CD1 4.25Å; L109-I127 HydrophobicContact CG-CB 4.43Å; L109-I127 PolarHBondContact N-O 2.8Å; L109-I297 HydrophobicContact CB-CG2 4.06Å; L109-I297 HydrophobicContact CD1-CD1 4.23Å; L109-I297 HydrophobicContact CD2-CG2 4.36Å; L109-V300 HydrophobicContact CD2-CG2 4.27Å; L109-I318 HydrophobicContact CD2-CD1 3.61Å
110L98.3Very high94.5Very high0 Ų030 Ų300%019%0.19CC..EExtended strand (participates in β ladder)trans-107147.4-169.5-54.9174.6000111.1K108 T114 L116 F119 G298 A299K108-L110 HydrophobicContact CB-CD2 3.98Å; L110-T114 HydrophobicContact CB-CG2 4.44Å; L110-T114 HydrophobicContact CD1-CG2 4.31Å; L110-L116 HydrophobicContact CD1-CD2 4.34Å; L110-F119 HydrophobicContact CD1-CD2 4.14Å; L110-F119 HydrophobicContact CD1-CE2 3.96Å; L110-F119 HydrophobicContact CD1-CZ 4.32Å; L110-F119 HydrophobicContact CD2-CD2 4.41Å; L110-F119 HydrophobicContact CD2-CE2 3.74Å; L110-F119 HydrophobicContact CD2-CZ 4.37Å; L110-F119 HydrophobicContact CG-CE2 4.49Å; L110-G298 PolarHBondContact O-N 2.84Å; L110-A299 HydrophobicContact CB-CB 3.95Å; L110-A299 HydrophobicContact CD1-CB 4.07Å; L110-A299 PolarHBondContact N-O 3.29Å; L110-A299 PolarHBondContact O-N 3.01Å
111P97.3Very high94.8Very high30 Ų3032.7 Ų32.720%0.19521%0.21CC..EExtended strand (participates in β ladder)trans-55.9148.3174.4-23.931.9000113.1G113 T114 P124 H126 S296P111-G113 PolarHBondContact O-N 2.85Å; P111-T114 WeakPolarHBondContact CD-OG1 3.24Å; P111-T114 WeakPolarHBondContact O-CB 3.22Å; P111-T114 PolarHBondContact O-N 2.94Å; P111-T114 PolarHBondContact O-OG1 3.34Å; P111-P124 WeakPolarHBondContact CD-O 3.49Å; P111-P124 HydrophobicContact CG-CB 4.49Å; P111-H126 WeakPolarHBondContact CA-NE2 3.4Å; P111-S296 CarbonylContact C-O 3.46Å; P111-S296 VanDerWaalsContact CA-O 3.27Å; P111-S296 WeakPolarHBondContact CA-O 3.47Å
112A96Very high95.3Very high45 Ų4535.3 Ų35.337%0.37222%0.216SC..THydrogen-bonded Turntrans-59.1134.3167.200000110.3S296A112-S296 VanDerWaalsContact CB-OG 3.25Å; A112-S296 WeakPolarHBondContact CB-OG 3.3Å; A112-S296 PolarHBondContact N-O 3.41Å
113G95.5Very high95.7Very high84 Ų8434.9 Ų34.987%0.86621%0.212SC*.THydrogen-bonded Turntrans86.23.7-176.500000115.4P111 N115P111-G113 PolarHBondContact O-N 2.85Å; G113-N115 PolarHBondContact O-N 3.27Å
114T97.4Very high96.3Very high26 Ų2638.4 Ų38.416%0.1624%0.235CC..  trans-54.9132.6172.8-61.50000111L110 P111 L116 T123L110-T114 HydrophobicContact CB-CG2 4.44Å; L110-T114 HydrophobicContact CD1-CG2 4.31Å; P111-T114 WeakPolarHBondContact CD-OG1 3.24Å; P111-T114 WeakPolarHBondContact O-CB 3.22Å; P111-T114 PolarHBondContact O-N 2.94Å; P111-T114 PolarHBondContact O-OG1 3.34Å; T114-L116 HydrophobicContact CG2-CD2 4.15Å; T114-L116 PolarHBondContact O-N 2.95Å; T114-T123 HydrophobicContact CG2-CG2 3.67Å
115N97.4Very high96.7Very high95 Ų9538.4 Ų38.451%0.50823%0.233SC..  trans-77.9102173.8-174.84.2000110.3G113 S117 E118 F119G113-N115 PolarHBondContact O-N 3.27Å; N115-S117 VanDerWaalsContact C-N 3.29Å; N115-S117 PolarHBondContact O-N 3.36Å; N115-S117 PolarHBondContact OD1-N 3.41Å; N115-S117 PolarHBondContact OD1-OG 3.47Å; N115-E118 WeakPolarHBondContact ND2-CG 3.48Å; N115-E118 PolarHBondContact O-N 3.1Å; N115-F119 PolarHBondContact O-N 3.32Å
116L97.6Very high96.8Very high13 Ų1339.7 Ų39.77%0.06824%0.238CC..G310 helixtrans-68.3-25.7-174.4-55.9-166.6000113.5V34 S74 K76 L110 T114 E118 F119 A299V34-L116 HydrophobicContact CB-CB 3.97Å; V34-L116 HydrophobicContact CG1-CB 4.06Å; V34-L116 HydrophobicContact CG2-CB 4.25Å; V34-L116 HydrophobicContact CG2-CD1 4.23Å; S74-L116 WeakPolarHBondContact OG-CB 3.5Å; S74-L116 WeakPolarHBondContact OG-CD2 3.4Å; K76-L116 HydrophobicContact CG-CD1 3.83Å; L110-L116 HydrophobicContact CD1-CD2 4.34Å; T114-L116 HydrophobicContact CG2-CD2 4.15Å; T114-L116 PolarHBondContact O-N 2.95Å; L116-E118 PolarHBondContact O-N 2.97Å; L116-F119 WeakPolarHBondContact O-CB 3.41Å; L116-F119 PolarHBondContact O-N 3.27Å; L116-A299 HydrophobicContact CD2-CB 3.82Å
117S96.2Very high96.8Very high37 Ų3737.8 Ų37.826%0.25923%0.231SC..G310 helixtrans-73.5-17.117871.10000113.2S36 N37 N115S36-S117 PolarHBondContact OG-O 3.41Å; N37-S117 PolarHBondContact N-O 3.46Å; N115-S117 VanDerWaalsContact C-N 3.29Å; N115-S117 PolarHBondContact O-N 3.36Å; N115-S117 PolarHBondContact OD1-N 3.41Å; N115-S117 PolarHBondContact OD1-OG 3.47Å
118E96.1Very high96.8Very high85 Ų8538.6 Ų38.640%0.39724%0.235SC..G310 helixtrans-109.512.3178-67.6-61.9144.200111.8H38 N115 L116 N120H38-E118 IonicContact CE1-OE2 3.03Å; H38-E118 IonicContact CG-OE2 3.64Å; H38-E118 IonicContact ND1-OE2 2.7Å; H38-E118 PolarHBondContact ND1-OE2 2.92Å; N115-E118 WeakPolarHBondContact ND2-CG 3.48Å; N115-E118 PolarHBondContact O-N 3.1Å; L116-E118 PolarHBondContact O-N 2.97Å; E118-N120 PolarHBondContact O-N 3.5Å; E118-N120 PolarHBondContact O-ND2 2.98Å
119F97.1Very high96.8Very high0 Ų038.4 Ų38.40%023%0.234CC..  trans-61.9130.9-176.5177.1-129.2000111.6S36 Q72 K108 L110 N115 L116 T123 F302 D303S36-F119 WeakPolarHBondContact CB-O 3.41Å; S36-F119 PolarHBondContact OG-N 2.94Å; S36-F119 PolarHBondContact OG-O 3.39Å; Q72-F119 HydrophobicContact CB-CD1 4.14Å; Q72-F119 PolarHBondContact OE1-O 3.03Å; K108-F119 HydrophobicContact CD-CE2 4.35Å; K108-F119 HydrophobicContact CD-CZ 4.19Å; L110-F119 HydrophobicContact CD1-CD2 4.14Å; L110-F119 HydrophobicContact CD1-CE2 3.96Å; L110-F119 HydrophobicContact CD1-CZ 4.32Å; L110-F119 HydrophobicContact CD2-CD2 4.41Å; L110-F119 HydrophobicContact CD2-CE2 3.74Å; L110-F119 HydrophobicContact CD2-CZ 4.37Å; L110-F119 HydrophobicContact CG-CE2 4.49Å; N115-F119 PolarHBondContact O-N 3.32Å; L116-F119 WeakPolarHBondContact O-CB 3.41Å; L116-F119 PolarHBondContact O-N 3.27Å; F119-T123 HydrophobicContact CD2-CG2 3.85Å; F119-T123 HydrophobicContact CE2-CG2 4.36Å; F119-F302 WeakPolarHBondContact CE1-O 3.39Å; F119-D303 HydrophobicContact CE1-CB 3.85Å; F119-D303 HydrophobicContact CE2-CB 4.3Å; F119-D303 HydrophobicContact CZ-CB 3.57Å
120N95.4Very high96.8Very high13 Ų1338.4 Ų38.47%0.0723%0.234CC..  trans-160.8-177.4-174.761.844.5000111.9H38 E118 K122 T123H38-N120 HydrophobicContact CB-CB 4.15Å; H38-N120 PolarHBondContact CD2-ND2 2.88Å; H38-N120 PolarHBondContact CE1-ND2 2.76Å; H38-N120 VanDerWaalsContact CE1-ND2 3.31Å; H38-N120 PolarHBondContact ND1-ND2 2.76Å; H38-N120 PolarHBondContact NE2-ND2 2.85Å; H38-N120 VanDerWaalsContact NE2-ND2 3.15Å; E118-N120 PolarHBondContact O-N 3.5Å; E118-N120 PolarHBondContact O-ND2 2.98Å; N120-K122 PolarHBondContact O-N 2.72Å; N120-K122 VanDerWaalsContact O-N 3.15Å; N120-K122 WeakPolarHBondContact OD1-CA 3.45Å; N120-K122 WeakPolarHBondContact OD1-CB 3.38Å; N120-K122 PolarHBondContact OD1-N 3.11Å; N120-T123 PolarHBondContact N-OG1 2.73Å; N120-T123 VanDerWaalsContact O-CB 3.29Å; N120-T123 WeakPolarHBondContact O-CB 3.45Å; N120-T123 PolarHBondContact O-N 2.94Å; N120-T123 PolarHBondContact O-OG1 2.79Å; N120-T123 PolarHBondContact OD1-N 2.95Å; N120-T123 PolarHBondContact OD1-OG1 2.79Å
121S93.2Very high96.7Very high61 Ų6138.7 Ų38.743%0.42724%0.236SC..THydrogen-bonded Turntrans-57.2-24.9177.6620000116.2D303S121-D303 WeakPolarHBondContact CA-OD2 3.32Å; S121-D303 PolarHBondContact N-OD1 2.92Å; S121-D303 PolarHBondContact N-OD2 2.67Å
122K94.6Very high96.5Very high170 Ų17038.2 Ų38.274%0.73923%0.232SC*.THydrogen-bonded Turntrans-95-6.8178.8-60.5177.9-176.7170.80113.1N120N120-K122 PolarHBondContact O-N 2.72Å; N120-K122 VanDerWaalsContact O-N 3.15Å; N120-K122 WeakPolarHBondContact OD1-CA 3.45Å; N120-K122 WeakPolarHBondContact OD1-CB 3.38Å; N120-K122 PolarHBondContact OD1-N 3.11Å
123T96.7Very high96.4Very high15 Ų1536.3 Ų36.39%0.09222%0.215CC..SBendtrans-63.5128.6-177.9-59.80000109.8T114 F119 N120 Y125T114-T123 HydrophobicContact CG2-CG2 3.67Å; F119-T123 HydrophobicContact CD2-CG2 3.85Å; F119-T123 HydrophobicContact CE2-CG2 4.36Å; N120-T123 PolarHBondContact N-OG1 2.73Å; N120-T123 VanDerWaalsContact O-CB 3.29Å; N120-T123 WeakPolarHBondContact O-CB 3.45Å; N120-T123 PolarHBondContact O-N 2.94Å; N120-T123 PolarHBondContact O-OG1 2.79Å; N120-T123 PolarHBondContact OD1-N 2.95Å; N120-T123 PolarHBondContact OD1-OG1 2.79Å; T123-Y125 PolarHBondContact O-N 3.18Å
124P96.5Very high96.2Very high77 Ų7735 Ų3550%0.519%0.192SC..  trans-57.2135.4175.3-24.934.5000111.3P111P111-P124 WeakPolarHBondContact CD-O 3.49Å; P111-P124 HydrophobicContact CG-CB 4.49Å
125Y97.5Very high95.7Very high6 Ų635.4 Ų35.42%0.02420%0.201CC..  trans-131.9162.5173.562.3-91.5000108.8K108 L109 T123 M128 R146 E151K108-Y125 HydrophobicContact CD-CD1 4.07Å; K108-Y125 HydrophobicContact CD-CG 4.26Å; K108-Y125 HydrophobicContact CG-CG 4.37Å; L109-Y125 WeakPolarHBondContact O-CA 2.97Å; L109-Y125 WeakPolarHBondContact O-CB 3.12Å; T123-Y125 PolarHBondContact O-N 3.18Å; Y125-M128 HydrophobicContact CD2-CB 4.11Å; Y125-M128 HydrophobicContact CE1-CE 4.25Å; Y125-M128 HydrophobicContact CE2-CB 3.62Å; Y125-R146 HydrophobicContact CD2-CB 4.18Å; Y125-R146 HydrophobicContact CE2-CB 4Å; Y125-R146 VanDerWaalsContact O-CB 3.3Å; Y125-R146 WeakPolarHBondContact O-CB 3.42Å; Y125-R146 WeakPolarHBondContact O-CD 3.45Å; Y125-E151 PolarHBondContact OH-OE1 3.2Å; Y125-E151 PolarHBondContact OH-OE2 3.27Å
126H97.1Very high95Very high32 Ų3238.4 Ų38.415%0.14822%0.216CC..SBendtrans-94.3-44.7175.1-65.6-47.7000111.3L109 P111 R146 H294 S296L109-H126 PolarHBondContact O-N 3.5Å; P111-H126 WeakPolarHBondContact CA-NE2 3.4Å; H126-R146 PolarHBondContact O-N 2.83Å; H126-H294 PolarHBondContact CD2-O 2.86Å; H126-H294 VanDerWaalsContact CD2-O 3.32Å; H126-H294 PolarHBondContact CE1-O 2.62Å; H126-H294 VanDerWaalsContact CE1-O 3.24Å; H126-H294 PolarHBondContact ND1-O 2.95Å; H126-H294 PolarHBondContact NE2-O 3.31Å; H126-S296 PolarHBondContact NE2-O 2.74Å
127I97.6Very high94.3Very high1 Ų147.1 Ų47.11%0.00526%0.256CS..EExtended strand (participates in β ladder)trans-137.3138.5-178.5-65.7169000109.3L88 K108 L109 F129 I144 I145 L171 I173L88-I127 HydrophobicContact CD2-CD1 3.33Å; K108-I127 CarbonylContact C-O 3.57Å; K108-I127 WeakPolarHBondContact CA-O 3.38Å; L109-I127 HydrophobicContact CB-CB 4.3Å; L109-I127 HydrophobicContact CD1-CB 4.23Å; L109-I127 HydrophobicContact CD1-CD1 4.25Å; L109-I127 HydrophobicContact CG-CB 4.43Å; L109-I127 PolarHBondContact N-O 2.8Å; I127-F129 HydrophobicContact CG2-CB 4.3Å; I127-I144 CarbonylContact C-O 3.57Å; I127-I144 VanDerWaalsContact CA-O 3.31Å; I127-I144 WeakPolarHBondContact CA-O 3.42Å; I127-I145 HydrophobicContact CG1-CG1 4.44Å; I127-L171 HydrophobicContact CG2-CD2 3.78Å; I127-I173 HydrophobicContact CD1-CD1 3.84Å
128M98.1Very high94Very high17 Ų1747.8 Ų47.88%0.08426%0.256CS..EExtended strand (participates in β ladder)trans-118.5128.4164.9176.4-161.1-74.300108.1Y106 I107 K108 Y125 A143 I144Y106-M128 HydrophobicContact CD2-CE 4.15Å; Y106-M128 HydrophobicContact CD2-CG 3.65Å; Y106-M128 HydrophobicContact CD2-SD 3.76Å; Y106-M128 HydrophobicContact CE2-CE 3.85Å; Y106-M128 HydrophobicContact CE2-CG 4.32Å; Y106-M128 HydrophobicContact CE2-SD 3.92Å; Y106-M128 HydrophobicContact CG-CG 4.01Å; Y106-M128 HydrophobicContact CG-SD 4.1Å; I107-M128 CarbonylContact O-C 3.56Å; I107-M128 WeakPolarHBondContact O-CA 3.37Å; K108-M128 HydrophobicContact CD-CE 4.42Å; K108-M128 HydrophobicContact CG-CB 4.21Å; K108-M128 HydrophobicContact CG-CE 4.43Å; K108-M128 HydrophobicContact CG-CG 4.22Å; Y125-M128 HydrophobicContact CD2-CB 4.11Å; Y125-M128 HydrophobicContact CE1-CE 4.25Å; Y125-M128 HydrophobicContact CE2-CB 3.62Å; M128-A143 WeakPolarHBondContact O-CA 3.07Å; M128-I144 HydrophobicContact CB-CB 4.21Å; M128-I144 PolarHBondContact N-O 3.08Å; M128-I144 PolarHBondContact O-N 3.28Å; M128-I144 HydrophobicContact SD-CD1 3.75Å; M128-I144 HydrophobicContact SD-CG1 4.34Å
129F98.6Very high93.9Very high0 Ų046.1 Ų46.10%025%0.247CC..EExtended strand (participates in β ladder)trans-144.1131.9-174.9174.4-114.1000112.6L90 Y92 Y106 I107 I127 I141 R142 A143 L171 I181L90-F129 HydrophobicContact CD2-CB 4.02Å; L90-F129 HydrophobicContact CD2-CD1 4.03Å; L90-F129 HydrophobicContact CD2-CG 4.47Å; L90-F129 HydrophobicContact CG-CD1 4.31Å; Y92-F129 HydrophobicContact CE1-CD1 4.11Å; Y92-F129 HydrophobicContact CE1-CE1 4.37Å; Y92-F129 PolarHBondContact OH-O 2.88Å; Y106-F129 WeakPolarHBondContact CA-O 3.22Å; I107-F129 PolarHBondContact N-O 3.3Å; I107-F129 PolarHBondContact O-N 2.82Å; I127-F129 HydrophobicContact CG2-CB 4.3Å; F129-I141 HydrophobicContact CD2-CG2 4.31Å; F129-I141 HydrophobicContact CE2-CG2 3.71Å; F129-I141 HydrophobicContact CZ-CG2 4.43Å; F129-R142 CarbonylContact C-O 3.56Å; F129-R142 VanDerWaalsContact CA-O 3.25Å; F129-R142 WeakPolarHBondContact CA-O 3.44Å; F129-R142 WeakPolarHBondContact CD2-O 3.2Å; F129-A143 HydrophobicContact CD2-CB 4.23Å; F129-L171 HydrophobicContact CB-CD2 4.11Å; F129-L171 HydrophobicContact CD1-CB 3.69Å; F129-L171 HydrophobicContact CD2-CB 3.96Å; F129-L171 HydrophobicContact CD2-CD2 4.25Å; F129-L171 HydrophobicContact CE1-CB 3.69Å; F129-L171 HydrophobicContact CE2-CB 3.97Å; F129-L171 HydrophobicContact CG-CB 3.82Å; F129-L171 HydrophobicContact CG-CD2 4.08Å; F129-L171 HydrophobicContact CZ-CB 3.84Å; F129-I181 HydrophobicContact CE2-CD1 4.47Å; F129-I181 HydrophobicContact CE2-CG1 4.18Å; F129-I181 HydrophobicContact CE2-CG2 3.86Å; F129-I181 HydrophobicContact CZ-CG2 4.13Å
130G98Very high93.8Very high0 Ų047.3 Ų47.30%025%0.254CS..EExtended strand (participates in β ladder)trans149176.5173.300000116.9Y92 I141 R142Y92-G130 WeakPolarHBondContact OH-CA 3.48Å; G130-I141 CarbonylContact O-C 3.5Å; G130-I141 WeakPolarHBondContact O-CA 3.28Å; G130-R142 PolarHBondContact N-O 3.46Å; G130-R142 PolarHBondContact O-N 2.91Å
131P96.8Very high93.9Very high6 Ų647 Ų474%0.03925%0.252CS..EExtended strand (participates in β ladder)trans-66.2143.9174.428.2-33.4000112.1Y92 V94 A105 Y106 V140 C160 Y169Y92-P131 WeakPolarHBondContact OH-CD 3.2Å; V94-P131 HydrophobicContact CB-CG 4.31Å; V94-P131 HydrophobicContact CG1-CG 4.32Å; V94-P131 HydrophobicContact CG2-CG 4Å; A105-P131 CarbonylContact C-O 3.56Å; A105-P131 WeakPolarHBondContact CA-O 3.47Å; A105-P131 HydrophobicContact CB-CG 3.93Å; A105-P131 PolarHBondContact N-O 3.34Å; A105-P131 WeakPolarHBondContact O-CD 3.28Å; Y106-P131 PolarHBondContact N-O 2.84Å; P131-V140 CarbonylContact C-O 3.49Å; P131-V140 WeakPolarHBondContact CA-O 3.17Å; P131-C160 HydrophobicContact CB-CB 3.75Å; P131-Y169 HydrophobicContact CB-CE1 4.13Å; P131-Y169 HydrophobicContact CB-CE2 4.34Å; P131-Y169 HydrophobicContact CG-CD2 4.17Å; P131-Y169 HydrophobicContact CG-CE1 4.2Å; P131-Y169 HydrophobicContact CG-CE2 3.72Å
132D93.7Very high94Very high20 Ų2048.1 Ų48.111%0.10725%0.247CC..EExtended strand (participates in β ladder)trans-139.7110.7175.9-174.626.6000108Y106 V140 R142Y106-D132 HydrophobicContact CD1-CB 4.22Å; D132-V140 HydrophobicContact CB-CG2 4.43Å; D132-V140 PolarHBondContact N-O 3.44Å; D132-V140 PolarHBondContact O-N 3.29Å; D132-R142 HydrophobicContact CB-CG 3.57Å; D132-R142 IonicContact OD2-CZ 3.94Å; D132-R142 IonicContact OD2-NE 3.9Å; D132-R142 PolarHBondContact OD2-NE 2.79Å; D132-R142 IonicContact OD2-NH2 2.96Å; D132-R142 PolarHBondContact OD2-NH2 2.61Å
133I93.1Very high94.1Very high5 Ų540.2 Ų40.23%0.02621%0.213CC..EExtended strand (participates in β ladder)trans-112.9125-178.2-64.8174.6000107.9I100 C102 A103 L138 R139 D162I100-I133 HydrophobicContact CG2-CG2 4.49Å; C102-I133 CarbonylContact C-O 3.49Å; C102-I133 WeakPolarHBondContact CA-O 3.49Å; A103-I133 CarbonylContact C-O 3.56Å; A103-I133 PolarHBondContact N-O 3.12Å; A103-I133 PolarHBondContact O-N 3.45Å; A103-I133 VanDerWaalsContact O-N 3.09Å; A103-I133 VanDerWaalsContact O-O 3.14Å; I133-L138 CarbonylContact C-O 3.52Å; I133-L138 VanDerWaalsContact CA-O 3.27Å; I133-L138 WeakPolarHBondContact CA-O 3.12Å; I133-R139 HydrophobicContact CG1-CG 4.5Å; I133-R139 HydrophobicContact CG2-CG 4.29Å; I133-D162 HydrophobicContact CD1-CB 4.15Å
134C90.6Very high94.2Very high56 Ų5640.2 Ų40.238%0.37821%0.212SC..EExtended strand (participates in β ladder)trans-151.799.9166.3-155.80000111.2N101 C102 L138N101-C134 CarbonylContact O-C 3.43Å; C102-C134 HydrophobicContact CB-CB 3.92Å; C102-C134 WeakPolarHBondContact CB-SG 3.43Å; C102-C134 WeakPolarHBondContact SG-CB 3.41Å; C102-C134 CovalentContact SG-SG 2.06Å; C102-C134 PolarHBondContact SG-SG 3.38Å; C134-L138 HydrophobicContact CB-CB 4.32Å; C134-L138 HydrophobicContact CB-CD2 3.89Å; C134-L138 PolarHBondContact N-O 2.91Å; C134-L138 WeakPolarHBondContact O-CB 3.24Å
135G87.6Confident94.1Very high35 Ų3536.8 Ų36.836%0.36119%0.19SC..THydrogen-bonded Turntrans77.2-158.1-174.200000112.7N101 R139N101-G135 PolarHBondContact O-N 3.1Å; G135-R139 PolarHBondContact O-NE 2.69Å; G135-R139 PolarHBondContact O-NH2 2.78Å
136I82.6Confident94Very high157 Ų15739.6 Ų39.681%0.80520%0.2SC*.THydrogen-bonded Turntrans-86.5-30178-60.9171.3000110.5
137E83.1Confident93.7Very high196 Ų19640.4 Ų40.492%0.91620%0.202SC*.THydrogen-bonded Turntrans-80-29.8-173.6-60.6-174.3168.100113.4
138L90.3Very high93.2Very high51 Ų5147 Ų4727%0.26724%0.237SC..EExtended strand (participates in β ladder)trans-111.991.8179.9-167.973.1000109.7I133 C134 V140I133-L138 CarbonylContact C-O 3.52Å; I133-L138 VanDerWaalsContact CA-O 3.27Å; I133-L138 WeakPolarHBondContact CA-O 3.12Å; C134-L138 HydrophobicContact CB-CB 4.32Å; C134-L138 HydrophobicContact CB-CD2 3.89Å; C134-L138 PolarHBondContact N-O 2.91Å; C134-L138 WeakPolarHBondContact O-CB 3.24Å; L138-V140 HydrophobicContact CD1-CG2 3.8Å; L138-V140 HydrophobicContact CG-CG2 4.31Å
139R93Very high92.7Very high51 Ų5148.8 Ų48.819%0.19226%0.26CS..EExtended strand (participates in β ladder)trans-134.276.6172.1-65.4-174.8176.4-116.3-20.6108.3I100 I133 G135 T159 C160 D162I100-R139 PolarHBondContact O-NH2 2.94Å; I133-R139 HydrophobicContact CG1-CG 4.5Å; I133-R139 HydrophobicContact CG2-CG 4.29Å; G135-R139 PolarHBondContact O-NE 2.69Å; G135-R139 PolarHBondContact O-NH2 2.78Å; R139-T159 WeakPolarHBondContact O-CA 3.31Å; R139-C160 PolarHBondContact O-N 2.85Å; R139-D162 WeakPolarHBondContact CD-OD2 3.34Å; R139-D162 IonicContact CZ-OD2 2.91Å; R139-D162 IonicContact NE-OD2 3.7Å; R139-D162 VanDerWaalsContact NH1-CB 3.3Å; R139-D162 IonicContact NH1-OD2 3.38Å; R139-D162 PolarHBondContact NH1-OD2 2.68Å
140V95.4Very high92.5Very high24 Ų2455.7 Ų55.715%0.14529%0.29CS..EExtended strand (participates in β ladder)trans-130.1153.8-167-61.90000112.7P131 D132 L138 L158P131-V140 CarbonylContact C-O 3.49Å; P131-V140 WeakPolarHBondContact CA-O 3.17Å; D132-V140 HydrophobicContact CB-CG2 4.43Å; D132-V140 PolarHBondContact N-O 3.44Å; D132-V140 PolarHBondContact O-N 3.29Å; L138-V140 HydrophobicContact CD1-CG2 3.8Å; L138-V140 HydrophobicContact CG-CG2 4.31Å; V140-L158 CarbonylContact C-O 3.46Å; V140-L158 WeakPolarHBondContact CA-O 3.45Å; V140-L158 WeakPolarHBondContact CB-O 3.36Å
141I97Very high92.4Very high6 Ų660.3 Ų60.33%0.03131%0.312CS..EExtended strand (participates in β ladder)trans-87112.9163.9-55.1178.1000107.1F129 G130 L158 C160 Y169 I181 V183F129-I141 HydrophobicContact CD2-CG2 4.31Å; F129-I141 HydrophobicContact CE2-CG2 3.71Å; F129-I141 HydrophobicContact CZ-CG2 4.43Å; G130-I141 CarbonylContact O-C 3.5Å; G130-I141 WeakPolarHBondContact O-CA 3.28Å; I141-L158 HydrophobicContact CB-CB 4.37Å; I141-L158 HydrophobicContact CB-CD2 4.26Å; I141-L158 HydrophobicContact CB-CG 4.39Å; I141-L158 HydrophobicContact CD1-CD2 3.81Å; I141-L158 HydrophobicContact CD1-CG 4.02Å; I141-L158 HydrophobicContact CG1-CD2 4.47Å; I141-L158 HydrophobicContact CG1-CG 4.44Å; I141-L158 PolarHBondContact N-O 3.04Å; I141-C160 HydrophobicContact CG1-CB 3.65Å; I141-Y169 HydrophobicContact CD1-CD1 3.96Å; I141-Y169 HydrophobicContact CD1-CE1 3.7Å; I141-Y169 HydrophobicContact CG1-CD1 4.26Å; I141-Y169 HydrophobicContact CG1-CE1 3.85Å; I141-I181 HydrophobicContact CD1-CG2 4.45Å; I141-I181 HydrophobicContact CG2-CG2 4.23Å; I141-V183 HydrophobicContact CD1-CG2 3.42Å; I141-V183 VanDerWaalsContact CD1-CG2 3.42Å
142R96.5Very high92.4Very high85 Ų8561.7 Ų61.732%0.32132%0.318SS..EExtended strand (participates in β ladder)trans-74.5131.1169.4-61.6-64.1-171.6172.85.1109F129 G130 D132F129-R142 CarbonylContact C-O 3.56Å; F129-R142 VanDerWaalsContact CA-O 3.25Å; F129-R142 WeakPolarHBondContact CA-O 3.44Å; F129-R142 WeakPolarHBondContact CD2-O 3.2Å; G130-R142 PolarHBondContact N-O 3.46Å; G130-R142 PolarHBondContact O-N 2.91Å; D132-R142 HydrophobicContact CB-CG 3.57Å; D132-R142 IonicContact OD2-CZ 3.94Å; D132-R142 IonicContact OD2-NE 3.9Å; D132-R142 PolarHBondContact OD2-NE 2.79Å; D132-R142 IonicContact OD2-NH2 2.96Å; D132-R142 PolarHBondContact OD2-NH2 2.61Å
143A97.4Very high92.5Very high4 Ų464.5 Ų64.53%0.03334%0.335CS..EExtended strand (participates in β ladder)trans-133.9114.5161.300000106.2M128 F129 L154 I181 F197M128-A143 WeakPolarHBondContact O-CA 3.07Å; F129-A143 HydrophobicContact CD2-CB 4.23Å; A143-L154 PolarHBondContact O-N 2.86Å; A143-I181 HydrophobicContact CB-CD1 3.85Å; A143-F197 HydrophobicContact CB-CE1 3.84Å; A143-F197 HydrophobicContact CB-CZ 3.82Å; A143-F197 VanDerWaalsContact O-CE1 3.31Å; A143-F197 WeakPolarHBondContact O-CE1 3.27Å
144I97Very high92.6Very high15 Ų1565.2 Ų65.28%0.07734%0.339CS..EExtended strand (participates in β ladder)trans-129.4128-177.5-46.3-172.7000108.1I127 M128 E151 F152 T153I127-I144 CarbonylContact C-O 3.57Å; I127-I144 VanDerWaalsContact CA-O 3.31Å; I127-I144 WeakPolarHBondContact CA-O 3.42Å; M128-I144 HydrophobicContact CB-CB 4.21Å; M128-I144 PolarHBondContact N-O 3.08Å; M128-I144 PolarHBondContact O-N 3.28Å; M128-I144 HydrophobicContact SD-CD1 3.75Å; M128-I144 HydrophobicContact SD-CG1 4.34Å; I144-E151 HydrophobicContact CG2-CB 3.76Å; I144-E151 HydrophobicContact CG2-CG 3.98Å; I144-F152 WeakPolarHBondContact CA-O 3.38Å; I144-T153 HydrophobicContact CD1-CG2 4.15Å; I144-T153 HydrophobicContact CG1-CG2 4.05Å; I144-T153 HydrophobicContact CG2-CG2 4.23Å
145I96.3Very high92.7Very high6 Ų668.1 Ų68.13%0.03135%0.345CS..EExtended strand (participates in β ladder)trans-108127.7173.2-62.3159.3000106.8I127 F152 I193 F197 L199I127-I145 HydrophobicContact CG1-CG1 4.44Å; I145-F152 PolarHBondContact N-O 2.85Å; I145-F152 WeakPolarHBondContact O-CB 3.32Å; I145-F152 PolarHBondContact O-N 2.69Å; I145-I193 HydrophobicContact CD1-CD1 3.25Å; I145-I193 HydrophobicContact CD1-CG1 3.34Å; I145-I193 HydrophobicContact CG1-CD1 4.46Å; I145-F197 HydrophobicContact CD1-CB 4.38Å; I145-F197 HydrophobicContact CD1-CD1 3.58Å; I145-F197 HydrophobicContact CD1-CD2 4.12Å; I145-F197 HydrophobicContact CD1-CE1 3.73Å; I145-F197 HydrophobicContact CD1-CE2 4.28Å; I145-F197 HydrophobicContact CD1-CG 3.78Å; I145-F197 HydrophobicContact CD1-CZ 4.09Å; I145-F197 HydrophobicContact CG1-CD1 4.07Å; I145-F197 HydrophobicContact CG1-CE1 4.06Å; I145-L199 HydrophobicContact CB-CD1 4.43Å; I145-L199 HydrophobicContact CD1-CD1 3.72Å; I145-L199 HydrophobicContact CG2-CD1 4.23Å; I145-L199 HydrophobicContact CG2-CD2 4.18Å
146R94.8Very high93Very high64 Ų6472 Ų7224%0.24235%0.352CS..EExtended strand (participates in β ladder)trans-106.3126.6178.5-176.3169.1-179.6134.7-3.8109.3Y125 H126 K150 E151Y125-R146 HydrophobicContact CD2-CB 4.18Å; Y125-R146 HydrophobicContact CE2-CB 4Å; Y125-R146 VanDerWaalsContact O-CB 3.3Å; Y125-R146 WeakPolarHBondContact O-CB 3.42Å; Y125-R146 WeakPolarHBondContact O-CD 3.45Å; H126-R146 PolarHBondContact O-N 2.83Å; R146-K150 CarbonylContact C-O 3.55Å; R146-K150 VanDerWaalsContact CA-O 3.26Å; R146-K150 WeakPolarHBondContact CA-O 3.4Å; R146-E151 HydrophobicContact CB-CG 4.33Å; R146-E151 HydrophobicContact CG-CG 4.21Å; R146-E151 IonicContact CZ-OE1 2.69Å; R146-E151 IonicContact NH1-OE1 2.85Å; R146-E151 PolarHBondContact NH1-OE1 2.93Å
147R89.6Confident93.4Very high50 Ų5069.5 Ų69.519%0.18935%0.346CS..EExtended strand (participates in β ladder)trans-141.4135178.1-161.3-172.574-153.4-16.8109.8G149 K150 F152 L199 I201R147-G149 PolarHBondContact O-N 2.89Å; R147-G149 VanDerWaalsContact O-N 3.15Å; R147-K150 PolarHBondContact N-O 3.43Å; R147-K150 PolarHBondContact O-N 3.44Å; R147-F152 HydrophobicContact CB-CE2 4.18Å; R147-L199 PolarHBondContact NH1-O 3.23Å; R147-I201 VanDerWaalsContact NH1-CG2 3.3Å
148D86.8Confident93.8Very high139 Ų13960.9 Ų60.974%0.74331%0.307SS*.THydrogen-bonded Turntrans52.837.7177.7-48.7-45.9000112.9K150D148-K150 PolarHBondContact O-N 3.39Å
149G89.3Confident94Very high55 Ų5562.8 Ų62.857%0.56732%0.32SS*.THydrogen-bonded Turntrans74.60-178.100000115.6R147R147-G149 PolarHBondContact O-N 2.89Å; R147-G149 VanDerWaalsContact O-N 3.15Å
150K93.6Very high94Very high145 Ų14560.8 Ų60.863%0.6331%0.314SS*.EExtended strand (participates in β ladder)trans-103.9144.8177-63.8-177.7-179.3-178.70111.2R146 R147 D148 F152R146-K150 CarbonylContact C-O 3.55Å; R146-K150 VanDerWaalsContact CA-O 3.26Å; R146-K150 WeakPolarHBondContact CA-O 3.4Å; R147-K150 PolarHBondContact N-O 3.43Å; R147-K150 PolarHBondContact O-N 3.44Å; D148-K150 PolarHBondContact O-N 3.39Å; K150-F152 HydrophobicContact CB-CE2 3.78Å; K150-F152 HydrophobicContact CB-CZ 4.18Å
151E95.8Very high93.9Very high97 Ų9762.1 Ų62.145%0.45332%0.318SS..EExtended strand (participates in β ladder)trans-99.7133.4176-74.3172.6-162.200110.5Y125 I144 R146Y125-E151 PolarHBondContact OH-OE1 3.2Å; Y125-E151 PolarHBondContact OH-OE2 3.27Å; I144-E151 HydrophobicContact CG2-CB 3.76Å; I144-E151 HydrophobicContact CG2-CG 3.98Å; R146-E151 HydrophobicContact CB-CG 4.33Å; R146-E151 HydrophobicContact CG-CG 4.21Å; R146-E151 IonicContact CZ-OE1 2.69Å; R146-E151 IonicContact NH1-OE1 2.85Å; R146-E151 PolarHBondContact NH1-OE1 2.93Å
152F96.6Very high93.5Very high35 Ų3565 Ų6515%0.15433%0.334CS..EExtended strand (participates in β ladder)trans-119.6115.1179.5-65-93000107.6I144 I145 R147 K150 F197 D198 L199I144-F152 WeakPolarHBondContact CA-O 3.38Å; I145-F152 PolarHBondContact N-O 2.85Å; I145-F152 WeakPolarHBondContact O-CB 3.32Å; I145-F152 PolarHBondContact O-N 2.69Å; R147-F152 HydrophobicContact CB-CE2 4.18Å; K150-F152 HydrophobicContact CB-CE2 3.78Å; K150-F152 HydrophobicContact CB-CZ 4.18Å; F152-F197 HydrophobicContact CB-CB 4.33Å; F152-F197 WeakPolarHBondContact CB-O 3.38Å; F152-F197 WeakPolarHBondContact O-CD1 3.38Å; F152-D198 WeakPolarHBondContact CD1-O 3.49Å; F152-D198 WeakPolarHBondContact CE1-O 3.25Å; F152-L199 HydrophobicContact CB-CD2 3.63Å; F152-L199 HydrophobicContact CB-CG 4.17Å; F152-L199 HydrophobicContact CD1-CD2 3.8Å; F152-L199 HydrophobicContact CD1-CG 4.34Å; F152-L199 HydrophobicContact CD2-CD2 3.43Å; F152-L199 VanDerWaalsContact CD2-CD2 3.43Å; F152-L199 HydrophobicContact CE1-CD2 4.29Å; F152-L199 HydrophobicContact CE2-CD2 3.97Å; F152-L199 HydrophobicContact CG-CD2 3.33Å; F152-L199 HydrophobicContact CG-CG 4.16Å; F152-L199 HydrophobicContact CZ-CD2 4.37Å
153T96.2Very high93.3Very high78 Ų7863.1 Ų63.148%0.47933%0.331SS..EExtended strand (participates in β ladder)trans-101.6152.3-177.760.50000110.4I144 K155I144-T153 HydrophobicContact CD1-CG2 4.15Å; I144-T153 HydrophobicContact CG1-CG2 4.05Å; I144-T153 HydrophobicContact CG2-CG2 4.23Å; T153-K155 PolarHBondContact O-N 3.28Å
154L94.4Very high93.1Very high20 Ų2065 Ų6511%0.10534%0.338CS..  trans-54.5127.3170.5-169.668.7000111.7A143 K156 L158 Y179 I181 M189 D196 F197A143-L154 PolarHBondContact O-N 2.86Å; L154-K156 WeakPolarHBondContact CD2-O 3.38Å; L154-K156 WeakPolarHBondContact CG-O 3.11Å; L154-K156 PolarHBondContact O-N 3.36Å; L154-L158 HydrophobicContact CD2-CB 4.46Å; L154-Y179 HydrophobicContact CD1-CE2 4.23Å; L154-Y179 WeakPolarHBondContact CD1-OH 3.46Å; L154-I181 HydrophobicContact CD2-CD1 4.09Å; L154-M189 HydrophobicContact CD1-SD 3.74Å; L154-M189 HydrophobicContact CD2-CE 3.98Å; L154-M189 HydrophobicContact CD2-SD 3.58Å; L154-M189 VanDerWaalsContact CD2-SD 3.58Å; L154-M189 HydrophobicContact CG-SD 3.96Å; L154-D196 HydrophobicContact CD1-CB 4.06Å; L154-F197 HydrophobicContact CB-CE1 4.25Å; L154-F197 HydrophobicContact CB-CZ 4.34Å; L154-F197 HydrophobicContact CD1-CD2 4.18Å; L154-F197 HydrophobicContact CD1-CE2 3.68Å; L154-F197 HydrophobicContact CD1-CZ 3.88Å
155K94.5Very high92.9Very high117 Ų11766.5 Ų66.551%0.50934%0.343SS..SBendtrans-63.9-40.6-178.5-76.2175.5-177.4172.80112.8T153 D195 D196 D198T153-K155 PolarHBondContact O-N 3.28Å; K155-D195 WeakPolarHBondContact CD-O 3.28Å; K155-D195 WeakPolarHBondContact CE-O 3.4Å; K155-D195 PolarHBondContact NZ-O 2.89Å; K155-D196 WeakPolarHBondContact CB-O 3.25Å; K155-D196 WeakPolarHBondContact CG-O 3.3Å; K155-D196 PolarHBondContact N-O 3.3Å; K155-D198 VanDerWaalsContact CE-CB 3.47Å; K155-D198 WeakPolarHBondContact CE-OD1 3.27Å; K155-D198 IonicContact NZ-OD1 2.58Å; K155-D198 PolarHBondContact NZ-OD1 2.91Å
156K92.4Very high92.7Very high116 Ų11667.2 Ų67.250%0.50435%0.348SS..SBendtrans-96.3118.2179.7-175179.3175.7-172.70108.7L154 M189 Y246L154-K156 WeakPolarHBondContact CD2-O 3.38Å; L154-K156 WeakPolarHBondContact CG-O 3.11Å; L154-K156 PolarHBondContact O-N 3.36Å; K156-M189 HydrophobicContact CB-CE 3.99Å; K156-M189 HydrophobicContact CD-CE 3.93Å; K156-M189 HydrophobicContact CG-CE 4Å; K156-Y246 PolarHBondContact NZ-OH 3.45Å; K156-Y246 VanDerWaalsContact NZ-OH 3.14Å
157P91.6Very high92.6Very high105 Ų10564.2 Ų64.268%0.68234%0.337SS*.  trans-62.6145.2175.827.2-33.7000110.1
158L92.1Very high92.8Very high16 Ų1662.1 Ų62.18%0.08433%0.329CS..  trans-123.4128.9178.4-17561.1000108.6V140 I141 L154 I181 R188 M189V140-L158 CarbonylContact C-O 3.46Å; V140-L158 WeakPolarHBondContact CA-O 3.45Å; V140-L158 WeakPolarHBondContact CB-O 3.36Å; I141-L158 HydrophobicContact CB-CB 4.37Å; I141-L158 HydrophobicContact CB-CD2 4.26Å; I141-L158 HydrophobicContact CB-CG 4.39Å; I141-L158 HydrophobicContact CD1-CD2 3.81Å; I141-L158 HydrophobicContact CD1-CG 4.02Å; I141-L158 HydrophobicContact CG1-CD2 4.47Å; I141-L158 HydrophobicContact CG1-CG 4.44Å; I141-L158 PolarHBondContact N-O 3.04Å; L154-L158 HydrophobicContact CD2-CB 4.46Å; L158-I181 HydrophobicContact CD2-CB 4.17Å; L158-I181 HydrophobicContact CD2-CD1 4.36Å; L158-I181 HydrophobicContact CD2-CG2 3.66Å; L158-R188 HydrophobicContact CD1-CB 4.13Å; L158-R188 HydrophobicContact CD2-CB 3.94Å; L158-M189 HydrophobicContact CB-CE 4.14Å; L158-M189 HydrophobicContact CD1-CE 4.13Å; L158-M189 HydrophobicContact CD2-CB 4.16Å
159T93.5Very high93.3Very high90 Ų9055.7 Ų55.755%0.55229%0.294SS*.BIsolated β-bridgetrans-74.1139.4178.752.20000111.1R139 R188R139-T159 WeakPolarHBondContact O-CA 3.31Å; T159-R188 PolarHBondContact O-NH2 2.75Å; T159-R188 PolarHBondContact OG1-NH2 2.98Å
160C93.6Very high93.6Very high9 Ų953 Ų536%0.06127%0.267CS..PPolyproline II helixtrans-89.4166.1170.365.40000111.1P131 R139 I141 Y169P131-C160 HydrophobicContact CB-CB 3.75Å; R139-C160 PolarHBondContact O-N 2.85Å; I141-C160 HydrophobicContact CG1-CB 3.65Å; C160-Y169 HydrophobicContact CB-CE1 4.31Å
161E92.1Very high93.9Very high52 Ų5246.3 Ų46.324%0.24324%0.238CC..PPolyproline II helixtrans-76.8141168.4-52.1-58.5133.400108.9H167 Y169 V183 R188E161-H167 VanDerWaalsContact CB-CD2 3.48Å; E161-H167 WeakPolarHBondContact CB-CD2 3.35Å; E161-H167 VanDerWaalsContact CB-NE2 3.34Å; E161-H167 WeakPolarHBondContact CB-NE2 3.37Å; E161-Y169 PolarHBondContact N-OH 3.36Å; E161-V183 HydrophobicContact CG-CG1 3.65Å; E161-R188 IonicContact OE1-CZ 3.82Å; E161-R188 IonicContact OE1-NH1 2.76Å; E161-R188 PolarHBondContact OE1-NH1 2.92Å; E161-R188 IonicContact OE1-NH2 3.03Å
162D90.2Very high93.9Very high67 Ų6741.7 Ų41.736%0.35822%0.217SC..  trans-131.711.5-17371.5-15.9000113.9I133 R139I133-D162 HydrophobicContact CD1-CB 4.15Å; R139-D162 WeakPolarHBondContact CD-OD2 3.34Å; R139-D162 IonicContact CZ-OD2 2.91Å; R139-D162 IonicContact NE-OD2 3.7Å; R139-D162 VanDerWaalsContact NH1-CB 3.3Å; R139-D162 IonicContact NH1-OD2 3.38Å; R139-D162 PolarHBondContact NH1-OD2 2.68Å
163D91.4Very high93.8Very high46 Ų4640.5 Ų40.525%0.24621%0.212CC..SBendtrans-77.3-177171.276.436.7000111.9Y165 H167D163-Y165 HydrophobicContact CB-CD2 4.29Å; D163-Y165 VanDerWaalsContact CG-CD2 3.49Å; D163-Y165 WeakPolarHBondContact OD1-CB 3.45Å; D163-Y165 VanDerWaalsContact OD1-CD2 3.28Å; D163-Y165 WeakPolarHBondContact OD1-CD2 2.98Å; D163-Y165 PolarHBondContact OD1-N 2.99Å; D163-Y165 WeakPolarHBondContact OD2-CD2 3.37Å; D163-H167 VanDerWaalsContact CG-NE2 3.31Å; D163-H167 IonicContact OD1-CD2 3.16Å; D163-H167 IonicContact OD1-NE2 3.65Å; D163-H167 PolarHBondContact OD1-NE2 3.08Å; D163-H167 IonicContact OD2-CE1 3.11Å; D163-H167 IonicContact OD2-NE2 3.74Å; D163-H167 PolarHBondContact OD2-NE2 2.81Å
164E93.1Very high93.7Very high43 Ų4337 Ų3720%0.20119%0.19CC..SBendtrans-90.1-1.8-174-58.3-178.4156.900113.9F52 N96 R98 N99 K344F52-E164 HydrophobicContact CE1-CB 4.49Å; F52-E164 HydrophobicContact CZ-CB 4.07Å; F52-E164 WeakPolarHBondContact CZ-O 3.45Å; N96-E164 CarbonylContact O-C 3.42Å; N96-E164 WeakPolarHBondContact O-CA 3.08Å; N96-E164 WeakPolarHBondContact O-CB 3.47Å; R98-E164 WeakPolarHBondContact CA-OE1 3.18Å; N99-E164 PolarHBondContact N-OE1 3.25Å; E164-K344 WeakPolarHBondContact OE2-CE 3.27Å; E164-K344 IonicContact OE2-NZ 3.62Å; E164-K344 PolarHBondContact OE2-NZ 3.3Å
165Y92.5Very high93.5Very high46 Ų4638.2 Ų38.218%0.1820%0.199CC..SBendtrans-88.8167-172.9-56.3-65.7000112.2F52 D163 H167 E340 K341 K344F52-Y165 HydrophobicContact CE2-CD1 4.01Å; F52-Y165 HydrophobicContact CE2-CE1 4.26Å; F52-Y165 HydrophobicContact CZ-CD1 4.47Å; D163-Y165 HydrophobicContact CB-CD2 4.29Å; D163-Y165 VanDerWaalsContact CG-CD2 3.49Å; D163-Y165 WeakPolarHBondContact OD1-CB 3.45Å; D163-Y165 VanDerWaalsContact OD1-CD2 3.28Å; D163-Y165 WeakPolarHBondContact OD1-CD2 2.98Å; D163-Y165 PolarHBondContact OD1-N 2.99Å; D163-Y165 WeakPolarHBondContact OD2-CD2 3.37Å; Y165-H167 PolarHBondContact O-CD2 2.96Å; Y165-E340 HydrophobicContact CD1-CG 4.45Å; Y165-K341 HydrophobicContact CE1-CB 4.09Å; Y165-K341 HydrophobicContact CE1-CG 4.09Å; Y165-K344 HydrophobicContact CE1-CB 4.03Å; Y165-K344 HydrophobicContact CE1-CG 4.16Å
166T92.9Very high93.3Very high21 Ų2134.2 Ų34.213%0.12918%0.183CC..EExtended strand (participates in β ladder)trans-72.2131.5172.4-59.30000109.8F168 F333 E340T166-F168 HydrophobicContact CG2-CE2 4.22Å; T166-F333 HydrophobicContact CG2-CE2 4.25Å; T166-F333 WeakPolarHBondContact O-CE2 3.41Å; T166-F333 VanDerWaalsContact O-CZ 3.27Å; T166-F333 WeakPolarHBondContact O-CZ 3.43Å; T166-E340 PolarHBondContact N-OE2 3.25Å; T166-E340 PolarHBondContact OG1-OE1 3.44Å
167H93Very high93.2Very high2 Ų229 Ų291%0.00916%0.16CC..EExtended strand (participates in β ladder)trans-128.4137.5175.1-71.4-78000111.9S93 V94 E161 D163 Y165 Y169 D184 R337S93-H167 CarbonylContact C-O 3.46Å; S93-H167 VanDerWaalsContact CA-O 3.25Å; S93-H167 WeakPolarHBondContact CA-O 3.37Å; V94-H167 PolarHBondContact N-O 3.35Å; V94-H167 PolarHBondContact O-N 2.91Å; E161-H167 VanDerWaalsContact CB-CD2 3.48Å; E161-H167 WeakPolarHBondContact CB-CD2 3.35Å; E161-H167 VanDerWaalsContact CB-NE2 3.34Å; E161-H167 WeakPolarHBondContact CB-NE2 3.37Å; D163-H167 VanDerWaalsContact CG-NE2 3.31Å; D163-H167 IonicContact OD1-CD2 3.16Å; D163-H167 IonicContact OD1-NE2 3.65Å; D163-H167 PolarHBondContact OD1-NE2 3.08Å; D163-H167 IonicContact OD2-CE1 3.11Å; D163-H167 IonicContact OD2-NE2 3.74Å; D163-H167 PolarHBondContact OD2-NE2 2.81Å; Y165-H167 PolarHBondContact O-CD2 2.96Å; H167-Y169 HydrophobicContact CB-CD2 4.47Å; H167-Y169 HydrophobicContact CB-CE2 3.77Å; H167-D184 VanDerWaalsContact CA-OD1 3.3Å; H167-D184 WeakPolarHBondContact CA-OD1 3.42Å; H167-D184 IonicContact CE1-OD2 2.72Å; H167-D184 PolarHBondContact CE1-OD2 3.33Å; H167-D184 IonicContact CG-OD1 2.64Å; H167-D184 IonicContact CG-OD2 3.5Å; H167-D184 IonicContact ND1-OD1 3.55Å; H167-D184 PolarHBondContact ND1-OD1 2.9Å; H167-D184 IonicContact ND1-OD2 3.87Å; H167-D184 PolarHBondContact ND1-OD2 3.39Å; H167-R337 PolarHBondContact CE1-NH2 2.85Å
168F94.3Very high93.3Very high5 Ų524.1 Ų24.12%0.02213%0.129CC..EExtended strand (participates in β ladder)trans-93125.2177.2-84.6-102000110.3Q91 T166 V183 D184 N315 F328 F333Q91-F168 HydrophobicContact CG-CD1 3.86Å; T166-F168 HydrophobicContact CG2-CE2 4.22Å; F168-V183 CarbonylContact O-C 3.59Å; F168-V183 WeakPolarHBondContact O-CA 3.47Å; F168-D184 PolarHBondContact N-OD1 3.39Å; F168-D184 PolarHBondContact O-N 2.85Å; F168-N315 HydrophobicContact CE1-CB 3.54Å; F168-N315 HydrophobicContact CZ-CB 3.73Å; F168-F328 HydrophobicContact CE1-CD1 4.27Å; F168-F328 AromaticContact CE1-CE1 3.55Å; F168-F328 HydrophobicContact CE1-CE1 3.55Å; F168-F328 AromaticContact CZ-CE1 3.9Å; F168-F328 HydrophobicContact CZ-CE1 3.9Å; F168-F333 HydrophobicContact CD2-CB 3.95Å; F168-F333 HydrophobicContact CD2-CD1 4.09Å; F168-F333 AromaticContact CD2-CD2 3.13Å; F168-F333 HydrophobicContact CD2-CD2 3.13Å; F168-F333 HydrophobicContact CD2-CE1 4.36Å; F168-F333 AromaticContact CD2-CE2 3.43Å; F168-F333 HydrophobicContact CD2-CE2 3.43Å; F168-F333 VanDerWaalsContact CD2-CE2 3.43Å; F168-F333 AromaticContact CD2-CG 3.44Å; F168-F333 HydrophobicContact CD2-CG 3.44Å; F168-F333 VanDerWaalsContact CD2-CG 3.44Å; F168-F333 HydrophobicContact CD2-CZ 4.03Å; F168-F333 HydrophobicContact CE2-CB 3.8Å; F168-F333 AromaticContact CE2-CD2 3.12Å; F168-F333 HydrophobicContact CE2-CD2 3.12Å; F168-F333 AromaticContact CE2-CE2 3.76Å; F168-F333 HydrophobicContact CE2-CE2 3.76Å; F168-F333 AromaticContact CE2-CG 3.63Å; F168-F333 HydrophobicContact CE2-CG 3.63Å; F168-F333 HydrophobicContact CG-CD2 4.35Å; F168-F333 HydrophobicContact CG-CG 4.33Å; F168-F333 HydrophobicContact CZ-CB 4.37Å; F168-F333 HydrophobicContact CZ-CD2 4.33Å
169Y96Very high93.4Very high4 Ų423.4 Ų23.42%0.01613%0.125CC..EExtended strand (participates in β ladder)trans-109120.5175.4-68.2-91.8000109Q91 Y92 V94 P131 I141 C160 E161 H167 V183Q91-Y169 WeakPolarHBondContact CA-O 3.43Å; Y92-Y169 PolarHBondContact N-O 2.99Å; Y92-Y169 PolarHBondContact O-N 3.22Å; V94-Y169 HydrophobicContact CB-CD2 4.34Å; V94-Y169 HydrophobicContact CB-CE2 4.13Å; V94-Y169 HydrophobicContact CG2-CD2 4.19Å; V94-Y169 HydrophobicContact CG2-CE2 4.38Å; P131-Y169 HydrophobicContact CB-CE1 4.13Å; P131-Y169 HydrophobicContact CB-CE2 4.34Å; P131-Y169 HydrophobicContact CG-CD2 4.17Å; P131-Y169 HydrophobicContact CG-CE1 4.2Å; P131-Y169 HydrophobicContact CG-CE2 3.72Å; I141-Y169 HydrophobicContact CD1-CD1 3.96Å; I141-Y169 HydrophobicContact CD1-CE1 3.7Å; I141-Y169 HydrophobicContact CG1-CD1 4.26Å; I141-Y169 HydrophobicContact CG1-CE1 3.85Å; C160-Y169 HydrophobicContact CB-CE1 4.31Å; E161-Y169 PolarHBondContact N-OH 3.36Å; H167-Y169 HydrophobicContact CB-CD2 4.47Å; H167-Y169 HydrophobicContact CB-CE2 3.77Å; Y169-V183 HydrophobicContact CD1-CG2 3.85Å; Y169-V183 HydrophobicContact CE1-CG1 4.49Å; Y169-V183 HydrophobicContact CE1-CG2 3.84Å
170T96.9Very high93.5Very high0 Ų019.2 Ų19.20%010%0.099CC..EExtended strand (participates in β ladder)trans-121.3127.8-178.7-32.80000110.3V89 L90 Q91 I172 I181 R182 V325V89-T170 HydrophobicContact CG1-CG2 3.96Å; L90-T170 CarbonylContact O-C 3.55Å; L90-T170 WeakPolarHBondContact O-CA 3.35Å; Q91-T170 HydrophobicContact CB-CG2 4.16Å; Q91-T170 PolarHBondContact OE1-OG1 2.92Å; T170-I172 HydrophobicContact CG2-CD1 4.37Å; T170-I172 HydrophobicContact CG2-CG1 4.03Å; T170-I181 CarbonylContact O-C 3.35Å; T170-I181 WeakPolarHBondContact O-CA 3.32Å; T170-R182 PolarHBondContact N-O 3.37Å; T170-R182 PolarHBondContact O-N 3.45Å; T170-V325 HydrophobicContact CG2-CG1 3.94Å
171L97.9Very high93.5Very high4 Ų418.8 Ų18.82%0.02110%0.097CC..EExtended strand (participates in β ladder)trans-110.8122.9166.2175.264.5000108.9V89 L90 I127 F129 I173 I181V89-L171 WeakPolarHBondContact CA-O 3.38Å; L90-L171 PolarHBondContact N-O 2.63Å; L90-L171 PolarHBondContact O-N 2.76Å; I127-L171 HydrophobicContact CG2-CD2 3.78Å; F129-L171 HydrophobicContact CB-CD2 4.11Å; F129-L171 HydrophobicContact CD1-CB 3.69Å; F129-L171 HydrophobicContact CD2-CB 3.96Å; F129-L171 HydrophobicContact CD2-CD2 4.25Å; F129-L171 HydrophobicContact CE1-CB 3.69Å; F129-L171 HydrophobicContact CE2-CB 3.97Å; F129-L171 HydrophobicContact CG-CB 3.82Å; F129-L171 HydrophobicContact CG-CD2 4.08Å; F129-L171 HydrophobicContact CZ-CB 3.84Å; L171-I173 HydrophobicContact CD1-CG1 4.26Å; L171-I173 HydrophobicContact CD2-CD1 4.21Å; L171-I173 HydrophobicContact CG-CD1 4.41Å; L171-I173 HydrophobicContact CG-CG1 4.31Å; L171-I181 HydrophobicContact CD1-CG1 3.9Å
172I96.1Very high93.5Very high0 Ų016.5 Ų16.50%09%0.086CC..EExtended strand (participates in β ladder)trans-115.2128.9173.6-58169.4000107.8L88 V89 T170 H174 Y179 E180 T322 F326L88-I172 CarbonylContact O-C 3.13Å; L88-I172 VanDerWaalsContact O-CA 3.32Å; L88-I172 WeakPolarHBondContact O-CA 3.38Å; V89-I172 HydrophobicContact CG1-CG1 3.97Å; V89-I172 HydrophobicContact CG2-CG1 4.29Å; V89-I172 HydrophobicContact CG2-CG2 4.37Å; T170-I172 HydrophobicContact CG2-CD1 4.37Å; T170-I172 HydrophobicContact CG2-CG1 4.03Å; I172-H174 VanDerWaalsContact CG2-CE1 3.45Å; I172-H174 WeakPolarHBondContact CG2-CE1 3.37Å; I172-H174 WeakPolarHBondContact CG2-NE2 3.41Å; I172-Y179 CarbonylContact O-C 3.53Å; I172-Y179 WeakPolarHBondContact O-CA 3.48Å; I172-Y179 VanDerWaalsContact O-CB 3.26Å; I172-Y179 WeakPolarHBondContact O-CB 3.13Å; I172-E180 HydrophobicContact CB-CB 4.26Å; I172-E180 PolarHBondContact N-O 2.82Å; I172-E180 PolarHBondContact O-N 3.31Å; I172-T322 HydrophobicContact CD1-CG2 3.99Å; I172-T322 HydrophobicContact CG1-CG2 4.36Å; I172-T322 HydrophobicContact CG2-CG2 3.65Å; I172-F326 HydrophobicContact CD1-CE1 3.83Å; I172-F326 HydrophobicContact CD1-CZ 3.7Å
173I95.5Very high93.6Very high10 Ų1013.5 Ų13.55%0.0517%0.07CC..EExtended strand (participates in β ladder)trans-123.4120.9170.2-62.1167.8000108S87 L88 I127 L171 I193S87-I173 CarbonylContact C-O 3.52Å; S87-I173 VanDerWaalsContact CA-O 3.22Å; S87-I173 WeakPolarHBondContact CA-O 3.41Å; L88-I173 HydrophobicContact CB-CB 4.37Å; L88-I173 HydrophobicContact CD2-CD1 4.28Å; L88-I173 PolarHBondContact N-O 2.81Å; L88-I173 PolarHBondContact O-N 2.92Å; I127-I173 HydrophobicContact CD1-CD1 3.84Å; L171-I173 HydrophobicContact CD1-CG1 4.26Å; L171-I173 HydrophobicContact CD2-CD1 4.21Å; L171-I173 HydrophobicContact CG-CD1 4.41Å; L171-I173 HydrophobicContact CG-CG1 4.31Å; I173-I193 HydrophobicContact CB-CD1 4.49Å; I173-I193 HydrophobicContact CD1-CD1 3.54Å; I173-I193 HydrophobicContact CG1-CD1 3.82Å; I173-I193 HydrophobicContact CG2-CD1 3.83Å
174H93.3Very high93.5Very high5 Ų512.1 Ų12.12%0.0236%0.062CC..  trans-92.7157.7-176.9-66.4-68.2000112.5S87 I172 N176 Q177 T178 G273S87-H174 PolarHBondContact OG-ND1 2.82Å; I172-H174 VanDerWaalsContact CG2-CE1 3.45Å; I172-H174 WeakPolarHBondContact CG2-CE1 3.37Å; I172-H174 WeakPolarHBondContact CG2-NE2 3.41Å; H174-N176 WeakPolarHBondContact CB-OD1 3.35Å; H174-N176 PolarHBondContact O-N 2.86Å; H174-N176 VanDerWaalsContact O-N 3.1Å; H174-Q177 PolarHBondContact O-N 2.87Å; H174-T178 PolarHBondContact CD2-OG1 2.89Å; H174-T178 PolarHBondContact N-O 2.76Å; H174-G273 VanDerWaalsContact CD2-CA 3.42Å; H174-G273 WeakPolarHBondContact CD2-CA 3.47Å; H174-G273 VanDerWaalsContact NE2-CA 3.33Å; H174-G273 WeakPolarHBondContact NE2-CA 2.95Å
175P91.3Very high93.1Very high44 Ų4410.1 Ų10.129%0.2865%0.053SC..THydrogen-bonded Turntrans-57.5-27.7177.7-23.530.1000114.7Q177P175-Q177 PolarHBondContact O-N 3.37Å
176N89.5Confident92.6Very high34 Ų3413.7 Ų13.718%0.1827%0.066CC..THydrogen-bonded Turntrans-81.69.4178.272.3-17.6000113.4H174 T178 W216 R274H174-N176 WeakPolarHBondContact CB-OD1 3.35Å; H174-N176 PolarHBondContact O-N 2.86Å; H174-N176 VanDerWaalsContact O-N 3.1Å; N176-T178 VanDerWaalsContact C-N 3.28Å; N176-T178 PolarHBondContact ND2-OG1 2.93Å; N176-T178 PolarHBondContact O-N 2.91Å; N176-T178 PolarHBondContact OD1-N 2.86Å; N176-T178 VanDerWaalsContact OD1-N 3.14Å; N176-T178 PolarHBondContact OD1-OG1 2.84Å; N176-W216 HydrophobicContact CB-CH2 3.8Å; N176-W216 WeakPolarHBondContact ND2-CH2 2.98Å; N176-W216 WeakPolarHBondContact ND2-CZ2 3.2Å; N176-R274 PolarHBondContact ND2-O 2.06Å
177Q91.5Very high92.3Very high5 Ų513.5 Ų13.52%0.0237%0.065CC..SBendtrans68.520.1179.2-48.1-170.169.300114.8H174 P175 N192 I193 I194 L290H174-Q177 PolarHBondContact O-N 2.87Å; P175-Q177 PolarHBondContact O-N 3.37Å; Q177-N192 PolarHBondContact O-ND2 3.31Å; Q177-I193 HydrophobicContact CB-CG2 4.01Å; Q177-I193 WeakPolarHBondContact O-CG2 3.37Å; Q177-I193 PolarHBondContact O-N 2.8Å; Q177-I194 VanDerWaalsContact CD-CD1 3.49Å; Q177-L290 PolarHBondContact NE2-O 3.41Å
178T93.1Very high92.1Very high3 Ų315.2 Ų15.22%0.0187%0.071CC..EExtended strand (participates in β ladder)trans-88.8154.8162.364.10000110.9H174 N176 G191 R274 Q276H174-T178 PolarHBondContact CD2-OG1 2.89Å; H174-T178 PolarHBondContact N-O 2.76Å; N176-T178 VanDerWaalsContact C-N 3.28Å; N176-T178 PolarHBondContact ND2-OG1 2.93Å; N176-T178 PolarHBondContact O-N 2.91Å; N176-T178 PolarHBondContact OD1-N 2.86Å; N176-T178 VanDerWaalsContact OD1-N 3.14Å; N176-T178 PolarHBondContact OD1-OG1 2.84Å; T178-G191 WeakPolarHBondContact CA-O 3.4Å; T178-G191 VanDerWaalsContact CB-O 3.31Å; T178-G191 WeakPolarHBondContact CB-O 3.48Å; T178-R274 WeakPolarHBondContact CG2-O 3.5Å; T178-Q276 HydrophobicContact CG2-CB 4.03Å; T178-Q276 HydrophobicContact CG2-CG 3.7Å
179Y94.6Very high91.9Very high1 Ų115.5 Ų15.50%0.0047%0.073CC..EExtended strand (participates in β ladder)trans-134.8159.4176.375.7-77.9000110.5L154 I172 I181 M189 A190 G191 I193 D196 F197L154-Y179 HydrophobicContact CD1-CE2 4.23Å; L154-Y179 WeakPolarHBondContact CD1-OH 3.46Å; I172-Y179 CarbonylContact O-C 3.53Å; I172-Y179 WeakPolarHBondContact O-CA 3.48Å; I172-Y179 VanDerWaalsContact O-CB 3.26Å; I172-Y179 WeakPolarHBondContact O-CB 3.13Å; Y179-I181 HydrophobicContact CD2-CD1 4.47Å; Y179-I181 HydrophobicContact CD2-CG1 4.11Å; Y179-I181 HydrophobicContact CE2-CD1 4.1Å; Y179-I181 HydrophobicContact CE2-CG1 4.12Å; Y179-M189 HydrophobicContact CE2-CG 4.27Å; Y179-M189 WeakPolarHBondContact OH-CG 3.43Å; Y179-M189 PolarHBondContact OH-SD 3.09Å; Y179-M189 VanDerWaalsContact OH-SD 3.36Å; Y179-A190 WeakPolarHBondContact O-CA 3.37Å; Y179-A190 VanDerWaalsContact O-CB 3.24Å; Y179-A190 WeakPolarHBondContact O-CB 3.26Å; Y179-G191 PolarHBondContact N-O 3.09Å; Y179-G191 VanDerWaalsContact N-O 3.14Å; Y179-G191 PolarHBondContact O-N 3.4Å; Y179-I193 HydrophobicContact CD1-CB 4.09Å; Y179-I193 HydrophobicContact CD1-CG1 4.46Å; Y179-D196 HydrophobicContact CE1-CB 3.85Å; Y179-D196 WeakPolarHBondContact CE1-OD2 3.45Å; Y179-D196 WeakPolarHBondContact OH-CB 3.33Å; Y179-D196 PolarHBondContact OH-OD2 3.43Å; Y179-F197 HydrophobicContact CD1-CE2 4.23Å; Y179-F197 HydrophobicContact CD2-CE2 4.31Å; Y179-F197 HydrophobicContact CE1-CE2 4.05Å; Y179-F197 HydrophobicContact CE2-CE2 4.13Å; Y179-F197 HydrophobicContact CG-CE2 4.37Å
180E93.9Very high91.7Very high3 Ų316.6 Ų16.61%0.0148%0.082CC..EExtended strand (participates in β ladder)trans-132.5132.2169-56.1-176.2-174.600109I172 R182 M189 A190 Y271I172-E180 HydrophobicContact CB-CB 4.26Å; I172-E180 PolarHBondContact N-O 2.82Å; I172-E180 PolarHBondContact O-N 3.31Å; E180-R182 HydrophobicContact CB-CG 4.47Å; E180-R182 IonicContact OE2-CZ 2.68Å; E180-R182 VanDerWaalsContact OE2-CZ 3.27Å; E180-R182 IonicContact OE2-NE 2.85Å; E180-R182 PolarHBondContact OE2-NE 2.87Å; E180-R182 IonicContact OE2-NH2 3.98Å; E180-R182 PolarHBondContact OE2-NH2 2.97Å; E180-M189 CarbonylContact C-O 3.54Å; E180-M189 WeakPolarHBondContact CA-O 3.25Å; E180-A190 HydrophobicContact CB-CB 4.46Å; E180-A190 HydrophobicContact CG-CB 3.94Å; E180-Y271 WeakPolarHBondContact OE1-CE1 3.48Å; E180-Y271 PolarHBondContact OE1-OH 3.46Å
181I94.4Very high91.4Very high0 Ų017 Ų170%09%0.086CC..EExtended strand (participates in β ladder)trans-104.1121.3162.8-64170.7000106.6F129 I141 A143 L154 L158 T170 L171 Y179 R188 M189F129-I181 HydrophobicContact CE2-CD1 4.47Å; F129-I181 HydrophobicContact CE2-CG1 4.18Å; F129-I181 HydrophobicContact CE2-CG2 3.86Å; F129-I181 HydrophobicContact CZ-CG2 4.13Å; I141-I181 HydrophobicContact CD1-CG2 4.45Å; I141-I181 HydrophobicContact CG2-CG2 4.23Å; A143-I181 HydrophobicContact CB-CD1 3.85Å; L154-I181 HydrophobicContact CD2-CD1 4.09Å; L158-I181 HydrophobicContact CD2-CB 4.17Å; L158-I181 HydrophobicContact CD2-CD1 4.36Å; L158-I181 HydrophobicContact CD2-CG2 3.66Å; T170-I181 CarbonylContact O-C 3.35Å; T170-I181 WeakPolarHBondContact O-CA 3.32Å; L171-I181 HydrophobicContact CD1-CG1 3.9Å; Y179-I181 HydrophobicContact CD2-CD1 4.47Å; Y179-I181 HydrophobicContact CD2-CG1 4.11Å; Y179-I181 HydrophobicContact CE2-CD1 4.1Å; Y179-I181 HydrophobicContact CE2-CG1 4.12Å; I181-R188 PolarHBondContact O-N 2.91Å; I181-M189 HydrophobicContact CB-CB 4.4Å; I181-M189 PolarHBondContact N-O 2.87Å; I181-M189 PolarHBondContact O-N 3.28Å; I181-M189 VanDerWaalsContact O-N 3.11Å
182R92.7Very high91.1Very high4 Ų417 Ų172%0.0159%0.087CC..EExtended strand (participates in β ladder)trans-115.3146.7176.7-52.9177.8162.9-122-6.8110.2T170 E180 N185 R186 V187T170-R182 PolarHBondContact N-O 3.37Å; T170-R182 PolarHBondContact O-N 3.45Å; E180-R182 HydrophobicContact CB-CG 4.47Å; E180-R182 IonicContact OE2-CZ 2.68Å; E180-R182 VanDerWaalsContact OE2-CZ 3.27Å; E180-R182 IonicContact OE2-NE 2.85Å; E180-R182 PolarHBondContact OE2-NE 2.87Å; E180-R182 IonicContact OE2-NH2 3.98Å; E180-R182 PolarHBondContact OE2-NH2 2.97Å; R182-N185 PolarHBondContact NH1-O 3.2Å; R182-N185 PolarHBondContact NH1-OD1 2.8Å; R182-R186 CarbonylContact C-O 3.56Å; R182-R186 WeakPolarHBondContact CA-O 3.33Å; R182-R186 WeakPolarHBondContact CB-O 3.48Å; R182-V187 HydrophobicContact CG-CG2 4.14Å; R182-V187 VanDerWaalsContact CZ-CG2 3.5Å; R182-V187 VanDerWaalsContact NH2-CG2 3.35Å
183V91.4Very high91Very high4 Ų417 Ų172%0.0249%0.087CC..EExtended strand (participates in β ladder)trans-125.6127.3166.3177.70000106.6I141 E161 F168 Y169 N185 R186 R188I141-V183 HydrophobicContact CD1-CG2 3.42Å; I141-V183 VanDerWaalsContact CD1-CG2 3.42Å; E161-V183 HydrophobicContact CG-CG1 3.65Å; F168-V183 CarbonylContact O-C 3.59Å; F168-V183 WeakPolarHBondContact O-CA 3.47Å; Y169-V183 HydrophobicContact CD1-CG2 3.85Å; Y169-V183 HydrophobicContact CE1-CG1 4.49Å; Y169-V183 HydrophobicContact CE1-CG2 3.84Å; V183-N185 PolarHBondContact O-N 3.25Å; V183-R186 PolarHBondContact N-O 2.88Å; V183-R186 WeakPolarHBondContact O-CA 3.49Å; V183-R186 VanDerWaalsContact O-CB 3.31Å; V183-R186 WeakPolarHBondContact O-CB 3.29Å; V183-R186 PolarHBondContact O-N 2.93Å; V183-R188 HydrophobicContact CB-CG 3.8Å; V183-R188 HydrophobicContact CG2-CG 3.79Å
184D89.1Confident90.8Very high16 Ų1616.6 Ų16.69%0.0868%0.084CC..THydrogen-bonded Turntrans53.645.8-178.7-58.6-19.6000111.3H167 F168 R186 F257 F333 R337H167-D184 VanDerWaalsContact CA-OD1 3.3Å; H167-D184 WeakPolarHBondContact CA-OD1 3.42Å; H167-D184 IonicContact CE1-OD2 2.72Å; H167-D184 PolarHBondContact CE1-OD2 3.33Å; H167-D184 IonicContact CG-OD1 2.64Å; H167-D184 IonicContact CG-OD2 3.5Å; H167-D184 IonicContact ND1-OD1 3.55Å; H167-D184 PolarHBondContact ND1-OD1 2.9Å; H167-D184 IonicContact ND1-OD2 3.87Å; H167-D184 PolarHBondContact ND1-OD2 3.39Å; F168-D184 PolarHBondContact N-OD1 3.39Å; F168-D184 PolarHBondContact O-N 2.85Å; D184-R186 PolarHBondContact O-N 3.05Å; D184-F257 WeakPolarHBondContact O-CD2 3.48Å; D184-F257 WeakPolarHBondContact O-CE2 3.35Å; D184-F333 HydrophobicContact CB-CE1 3.68Å; D184-F333 HydrophobicContact CB-CZ 4.33Å; D184-F333 WeakPolarHBondContact OD1-CE1 3.13Å; D184-F333 VanDerWaalsContact OD1-CZ 3.27Å; D184-F333 WeakPolarHBondContact OD1-CZ 3.3Å; D184-R337 IonicContact OD2-CZ 2.78Å; D184-R337 IonicContact OD2-NH1 3.44Å; D184-R337 PolarHBondContact OD2-NH1 3.02Å; D184-R337 IonicContact OD2-NH2 3.49Å
185N85.6Confident90.8Very high1 Ų118.5 Ų18.51%0.00510%0.095CC..THydrogen-bonded Turntrans56.43-174.4-160.25.5000115.4R182 V183 F257 G259 R267 F326 D329R182-N185 PolarHBondContact NH1-O 3.2Å; R182-N185 PolarHBondContact NH1-OD1 2.8Å; V183-N185 PolarHBondContact O-N 3.25Å; N185-F257 HydrophobicContact CB-CE2 3.7Å; N185-F257 HydrophobicContact CB-CZ 3.57Å; N185-G259 PolarHBondContact ND2-O 3.06Å; N185-G259 WeakPolarHBondContact O-CA 3.5Å; N185-R267 PolarHBondContact ND2-NH2 3Å; N185-F326 VanDerWaalsContact OD1-CD1 3.23Å; N185-F326 WeakPolarHBondContact OD1-CD1 3.14Å; N185-D329 HydrophobicContact CB-CB 4.02Å; N185-D329 WeakPolarHBondContact CB-OD2 3.26Å
186R82.2Confident90.9Very high121 Ų12118.7 Ų18.746%0.4579%0.093SC..EExtended strand (participates in β ladder)trans-85.5130.4172.2179.7-179.2178.4-159.13.1109.3R182 V183 D184 R188 V258R182-R186 CarbonylContact C-O 3.56Å; R182-R186 WeakPolarHBondContact CA-O 3.33Å; R182-R186 WeakPolarHBondContact CB-O 3.48Å; V183-R186 PolarHBondContact N-O 2.88Å; V183-R186 WeakPolarHBondContact O-CA 3.49Å; V183-R186 VanDerWaalsContact O-CB 3.31Å; V183-R186 WeakPolarHBondContact O-CB 3.29Å; V183-R186 PolarHBondContact O-N 2.93Å; D184-R186 PolarHBondContact O-N 3.05Å; R186-R188 PolarHBondContact O-N 2.85Å; R186-V258 HydrophobicContact CB-CB 4.28Å; R186-V258 HydrophobicContact CG-CB 3.95Å; R186-V258 HydrophobicContact CG-CG1 4.22Å; R186-V258 HydrophobicContact CG-CG2 4.43Å
187V86.4Confident91.2Very high18 Ų1817.3 Ų17.311%0.1099%0.086CC..EExtended strand (participates in β ladder)trans-69120.5173.9-170.30000110.3R182 M189 A190 F242R182-V187 HydrophobicContact CG-CG2 4.14Å; R182-V187 VanDerWaalsContact CZ-CG2 3.5Å; R182-V187 VanDerWaalsContact NH2-CG2 3.35Å; V187-M189 WeakPolarHBondContact CG1-O 3.47Å; V187-A190 HydrophobicContact CG1-CB 4.18Å; V187-F242 HydrophobicContact CB-CE2 4.05Å; V187-F242 HydrophobicContact CB-CZ 4.1Å; V187-F242 HydrophobicContact CG1-CE2 3.6Å; V187-F242 HydrophobicContact CG1-CZ 3.41Å; V187-F242 VanDerWaalsContact CG1-CZ 3.41Å; V187-F242 HydrophobicContact CG2-CE2 3.9Å; V187-F242 HydrophobicContact CG2-CZ 4.45Å
188R88.4Confident91.2Very high37 Ų3721.3 Ų21.314%0.1411%0.108CC..EExtended strand (participates in β ladder)trans-102.4-30.5179.3-68.1-65-65-77.8-0.5112L158 T159 E161 I181 V183 R186L158-R188 HydrophobicContact CD1-CB 4.13Å; L158-R188 HydrophobicContact CD2-CB 3.94Å; T159-R188 PolarHBondContact O-NH2 2.75Å; T159-R188 PolarHBondContact OG1-NH2 2.98Å; E161-R188 IonicContact OE1-CZ 3.82Å; E161-R188 IonicContact OE1-NH1 2.76Å; E161-R188 PolarHBondContact OE1-NH1 2.92Å; E161-R188 IonicContact OE1-NH2 3.03Å; I181-R188 PolarHBondContact O-N 2.91Å; V183-R188 HydrophobicContact CB-CG 3.8Å; V183-R188 HydrophobicContact CG2-CG 3.79Å; R186-R188 PolarHBondContact O-N 2.85Å
189M90.1Very high91.1Very high12 Ų1221.3 Ų21.36%0.05911%0.107CC..EExtended strand (participates in β ladder)trans-151.7146169.9-167.2166.6-58.600110.3L154 K156 L158 Y179 E180 I181 V187L154-M189 HydrophobicContact CD1-SD 3.74Å; L154-M189 HydrophobicContact CD2-CE 3.98Å; L154-M189 HydrophobicContact CD2-SD 3.58Å; L154-M189 VanDerWaalsContact CD2-SD 3.58Å; L154-M189 HydrophobicContact CG-SD 3.96Å; K156-M189 HydrophobicContact CB-CE 3.99Å; K156-M189 HydrophobicContact CD-CE 3.93Å; K156-M189 HydrophobicContact CG-CE 4Å; L158-M189 HydrophobicContact CB-CE 4.14Å; L158-M189 HydrophobicContact CD1-CE 4.13Å; L158-M189 HydrophobicContact CD2-CB 4.16Å; Y179-M189 HydrophobicContact CE2-CG 4.27Å; Y179-M189 WeakPolarHBondContact OH-CG 3.43Å; Y179-M189 PolarHBondContact OH-SD 3.09Å; Y179-M189 VanDerWaalsContact OH-SD 3.36Å; E180-M189 CarbonylContact C-O 3.54Å; E180-M189 WeakPolarHBondContact CA-O 3.25Å; I181-M189 HydrophobicContact CB-CB 4.4Å; I181-M189 PolarHBondContact N-O 2.87Å; I181-M189 PolarHBondContact O-N 3.28Å; I181-M189 VanDerWaalsContact O-N 3.11Å; V187-M189 WeakPolarHBondContact CG1-O 3.47Å
190A91.6Very high90.6Very high26 Ų2625 Ų2522%0.21513%0.125CC..EExtended strand (participates in β ladder)trans-151.5152.8165.700000110Y179 E180 V187 F242Y179-A190 WeakPolarHBondContact O-CA 3.37Å; Y179-A190 VanDerWaalsContact O-CB 3.24Å; Y179-A190 WeakPolarHBondContact O-CB 3.26Å; E180-A190 HydrophobicContact CB-CB 4.46Å; E180-A190 HydrophobicContact CG-CB 3.94Å; V187-A190 HydrophobicContact CG1-CB 4.18Å; A190-F242 HydrophobicContact CB-CE1 3.98Å; A190-F242 HydrophobicContact CB-CE2 3.61Å; A190-F242 HydrophobicContact CB-CZ 3.19Å
191G90.5Very high90.2Very high8 Ų827 Ų278%0.08214%0.135CC..EExtended strand (participates in β ladder)trans178.5-153-178.500000112.7T178 Y179 D196T178-G191 WeakPolarHBondContact CA-O 3.4Å; T178-G191 VanDerWaalsContact CB-O 3.31Å; T178-G191 WeakPolarHBondContact CB-O 3.48Å; Y179-G191 PolarHBondContact N-O 3.09Å; Y179-G191 VanDerWaalsContact N-O 3.14Å; Y179-G191 PolarHBondContact O-N 3.4Å; G191-D196 WeakPolarHBondContact CA-OD2 3.02Å
192N92.3Very high89.5Confident5 Ų531.6 Ų31.63%0.02716%0.164CC..EExtended strand (participates in β ladder)trans-96.7127.7172.8-161.6-95.6000108.7Q177 I194 D195 D196 R206 Q276Q177-N192 PolarHBondContact O-ND2 3.31Å; N192-I194 PolarHBondContact O-N 2.91Å; N192-I194 VanDerWaalsContact OD1-CB 3.23Å; N192-I194 WeakPolarHBondContact OD1-CB 3.48Å; N192-I194 PolarHBondContact OD1-N 2.98Å; N192-D195 HydrophobicContact CB-CB 4.05Å; N192-D195 PolarHBondContact O-N 3.47Å; N192-D195 PolarHBondContact OD1-N 3.38Å; N192-D196 WeakPolarHBondContact O-CB 3.5Å; N192-D196 PolarHBondContact O-N 3.42Å; N192-R206 PolarHBondContact ND2-NH1 2.96Å; N192-Q276 VanDerWaalsContact CG-OE1 3.3Å; N192-Q276 PolarHBondContact ND2-OE1 2.73Å
193I93Very high89.2Confident1 Ų139.6 Ų39.61%0.00520%0.196CC..Hα-helixtrans-63.9-32.3-179.5-156174.4000111.4I145 I173 Q177 Y179 F197 L199 L292I145-I193 HydrophobicContact CD1-CD1 3.25Å; I145-I193 HydrophobicContact CD1-CG1 3.34Å; I145-I193 HydrophobicContact CG1-CD1 4.46Å; I173-I193 HydrophobicContact CB-CD1 4.49Å; I173-I193 HydrophobicContact CD1-CD1 3.54Å; I173-I193 HydrophobicContact CG1-CD1 3.82Å; I173-I193 HydrophobicContact CG2-CD1 3.83Å; Q177-I193 HydrophobicContact CB-CG2 4.01Å; Q177-I193 WeakPolarHBondContact O-CG2 3.37Å; Q177-I193 PolarHBondContact O-N 2.8Å; Y179-I193 HydrophobicContact CD1-CB 4.09Å; Y179-I193 HydrophobicContact CD1-CG1 4.46Å; I193-F197 HydrophobicContact CB-CD2 4.49Å; I193-F197 HydrophobicContact CG1-CD2 3.71Å; I193-F197 HydrophobicContact CG1-CE2 3.87Å; I193-F197 HydrophobicContact CG1-CG 4.38Å; I193-F197 VanDerWaalsContact O-CB 3.28Å; I193-F197 WeakPolarHBondContact O-CB 3.19Å; I193-F197 WeakPolarHBondContact O-CD2 3.3Å; I193-F197 PolarHBondContact O-N 2.7Å; I193-L199 HydrophobicContact CG1-CD1 4.16Å; I193-L292 HydrophobicContact CG2-CD1 3.73Å
194I92.1Very high89Confident0 Ų040.2 Ų40.20%020%0.199CC..Hα-helixtrans-69.6-46.9178.8-55.6173.6000111.2Q177 N192 D198 L199 M204 Y279 L290 L292Q177-I194 VanDerWaalsContact CD-CD1 3.49Å; N192-I194 PolarHBondContact O-N 2.91Å; N192-I194 VanDerWaalsContact OD1-CB 3.23Å; N192-I194 WeakPolarHBondContact OD1-CB 3.48Å; N192-I194 PolarHBondContact OD1-N 2.98Å; I194-D198 WeakPolarHBondContact O-CA 3.42Å; I194-D198 PolarHBondContact O-N 3.19Å; I194-L199 HydrophobicContact CG2-CB 4.36Å; I194-L199 PolarHBondContact O-N 3.23Å; I194-M204 HydrophobicContact CB-CE 4.35Å; I194-M204 HydrophobicContact CD1-CE 4.05Å; I194-M204 HydrophobicContact CD1-SD 3.59Å; I194-M204 VanDerWaalsContact CD1-SD 3.59Å; I194-M204 HydrophobicContact CG1-SD 4.49Å; I194-M204 HydrophobicContact CG2-CE 3.16Å; I194-M204 HydrophobicContact CG2-SD 3.84Å; I194-Y279 HydrophobicContact CB-CD2 4.18Å; I194-Y279 HydrophobicContact CB-CE2 3.95Å; I194-Y279 HydrophobicContact CD1-CD2 3.22Å; I194-Y279 HydrophobicContact CD1-CE2 3.88Å; I194-Y279 HydrophobicContact CD1-CG 3.58Å; I194-Y279 HydrophobicContact CG1-CD2 4.21Å; I194-Y279 HydrophobicContact CG1-CE2 4.49Å; I194-Y279 HydrophobicContact CG2-CE2 4.18Å; I194-L290 HydrophobicContact CD1-CD2 3.88Å; I194-L292 HydrophobicContact CG1-CD1 3.81Å
195D92.5Very high89Confident45 Ų4542 Ų4224%0.24121%0.21CC..Hα-helixtrans-69.3-44.9-178.1-65.3-17.5000112K155 N192 H200 R206 Y279K155-D195 WeakPolarHBondContact CD-O 3.28Å; K155-D195 WeakPolarHBondContact CE-O 3.4Å; K155-D195 PolarHBondContact NZ-O 2.89Å; N192-D195 HydrophobicContact CB-CB 4.05Å; N192-D195 PolarHBondContact O-N 3.47Å; N192-D195 PolarHBondContact OD1-N 3.38Å; D195-H200 IonicContact OD1-CE1 3.68Å; D195-H200 IonicContact OD1-NE2 3.51Å; D195-R206 IonicContact OD1-NH2 3.98Å; D195-R206 IonicContact OD2-CZ 2.67Å; D195-R206 IonicContact OD2-NE 3.72Å; D195-R206 IonicContact OD2-NH2 2.84Å; D195-R206 PolarHBondContact OD2-NH2 3.21Å; D195-Y279 PolarHBondContact OD1-OH 3.26Å
196D94.2Very high89.2Confident48 Ų4844.1 Ų44.126%0.25722%0.218SC..Hα-helixtrans-81.5-18.6-169.6-63.8-13.5000112.7L154 K155 Y179 G191 N192L154-D196 HydrophobicContact CD1-CB 4.06Å; K155-D196 WeakPolarHBondContact CB-O 3.25Å; K155-D196 WeakPolarHBondContact CG-O 3.3Å; K155-D196 PolarHBondContact N-O 3.3Å; Y179-D196 HydrophobicContact CE1-CB 3.85Å; Y179-D196 WeakPolarHBondContact CE1-OD2 3.45Å; Y179-D196 WeakPolarHBondContact OH-CB 3.33Å; Y179-D196 PolarHBondContact OH-OD2 3.43Å; G191-D196 WeakPolarHBondContact CA-OD2 3.02Å; N192-D196 WeakPolarHBondContact O-CB 3.5Å; N192-D196 PolarHBondContact O-N 3.42Å
197F94.9Very high89.6Confident5 Ų539.6 Ų39.62%0.02220%0.203CC..Hα-helixtrans-109-2.5174.2-65.4-109000113.4A143 I145 F152 L154 Y179 I193 L199A143-F197 HydrophobicContact CB-CE1 3.84Å; A143-F197 HydrophobicContact CB-CZ 3.82Å; A143-F197 VanDerWaalsContact O-CE1 3.31Å; A143-F197 WeakPolarHBondContact O-CE1 3.27Å; I145-F197 HydrophobicContact CD1-CB 4.38Å; I145-F197 HydrophobicContact CD1-CD1 3.58Å; I145-F197 HydrophobicContact CD1-CD2 4.12Å; I145-F197 HydrophobicContact CD1-CE1 3.73Å; I145-F197 HydrophobicContact CD1-CE2 4.28Å; I145-F197 HydrophobicContact CD1-CG 3.78Å; I145-F197 HydrophobicContact CD1-CZ 4.09Å; I145-F197 HydrophobicContact CG1-CD1 4.07Å; I145-F197 HydrophobicContact CG1-CE1 4.06Å; F152-F197 HydrophobicContact CB-CB 4.33Å; F152-F197 WeakPolarHBondContact CB-O 3.38Å; F152-F197 WeakPolarHBondContact O-CD1 3.38Å; L154-F197 HydrophobicContact CB-CE1 4.25Å; L154-F197 HydrophobicContact CB-CZ 4.34Å; L154-F197 HydrophobicContact CD1-CD2 4.18Å; L154-F197 HydrophobicContact CD1-CE2 3.68Å; L154-F197 HydrophobicContact CD1-CZ 3.88Å; Y179-F197 HydrophobicContact CD1-CE2 4.23Å; Y179-F197 HydrophobicContact CD2-CE2 4.31Å; Y179-F197 HydrophobicContact CE1-CE2 4.05Å; Y179-F197 HydrophobicContact CE2-CE2 4.13Å; Y179-F197 HydrophobicContact CG-CE2 4.37Å; I193-F197 HydrophobicContact CB-CD2 4.49Å; I193-F197 HydrophobicContact CG1-CD2 3.71Å; I193-F197 HydrophobicContact CG1-CE2 3.87Å; I193-F197 HydrophobicContact CG1-CG 4.38Å; I193-F197 VanDerWaalsContact O-CB 3.28Å; I193-F197 WeakPolarHBondContact O-CB 3.19Å; I193-F197 WeakPolarHBondContact O-CD2 3.3Å; I193-F197 PolarHBondContact O-N 2.7Å; F197-L199 HydrophobicContact CB-CD1 3.95Å; F197-L199 HydrophobicContact CB-CG 3.95Å
198D92.2Very high89.8Confident90 Ų9047 Ų4748%0.48123%0.23SC..THydrogen-bonded Turntrans62.138.4-176.4-142.143.8000114.7F152 K155 I194 H200F152-D198 WeakPolarHBondContact CD1-O 3.49Å; F152-D198 WeakPolarHBondContact CE1-O 3.25Å; K155-D198 VanDerWaalsContact CE-CB 3.47Å; K155-D198 WeakPolarHBondContact CE-OD1 3.27Å; K155-D198 IonicContact NZ-OD1 2.58Å; K155-D198 PolarHBondContact NZ-OD1 2.91Å; I194-D198 WeakPolarHBondContact O-CA 3.42Å; I194-D198 PolarHBondContact O-N 3.19Å; D198-H200 PolarHBondContact O-N 3.33Å; D198-H200 VanDerWaalsContact O-N 3.11Å; D198-H200 IonicContact OD1-ND1 2.69Å
199L90.8Very high89.9Confident2 Ų253.6 Ų53.61%0.0126%0.26CS..  trans-79.915.4-175.6-70.3163.2000114.4I145 R147 F152 I193 I194 F197 I201 L292I145-L199 HydrophobicContact CB-CD1 4.43Å; I145-L199 HydrophobicContact CD1-CD1 3.72Å; I145-L199 HydrophobicContact CG2-CD1 4.23Å; I145-L199 HydrophobicContact CG2-CD2 4.18Å; R147-L199 PolarHBondContact NH1-O 3.23Å; F152-L199 HydrophobicContact CB-CD2 3.63Å; F152-L199 HydrophobicContact CB-CG 4.17Å; F152-L199 HydrophobicContact CD1-CD2 3.8Å; F152-L199 HydrophobicContact CD1-CG 4.34Å; F152-L199 HydrophobicContact CD2-CD2 3.43Å; F152-L199 VanDerWaalsContact CD2-CD2 3.43Å; F152-L199 HydrophobicContact CE1-CD2 4.29Å; F152-L199 HydrophobicContact CE2-CD2 3.97Å; F152-L199 HydrophobicContact CG-CD2 3.33Å; F152-L199 HydrophobicContact CG-CG 4.16Å; F152-L199 HydrophobicContact CZ-CD2 4.37Å; I193-L199 HydrophobicContact CG1-CD1 4.16Å; I194-L199 HydrophobicContact CG2-CB 4.36Å; I194-L199 PolarHBondContact O-N 3.23Å; F197-L199 HydrophobicContact CB-CD1 3.95Å; F197-L199 HydrophobicContact CB-CG 3.95Å; L199-I201 PolarHBondContact O-N 2.97Å; L199-L292 HydrophobicContact CB-CD1 4.28Å; L199-L292 HydrophobicContact CD1-CD1 3.8Å
200H85.1Confident89.9Confident80 Ų8054.9 Ų54.937%0.3727%0.269SS..  trans-55.4136.4-176.7-6564.6000111.9D195 D198 M204 Y279D195-H200 IonicContact OD1-CE1 3.68Å; D195-H200 IonicContact OD1-NE2 3.51Å; D198-H200 PolarHBondContact O-N 3.33Å; D198-H200 VanDerWaalsContact O-N 3.11Å; D198-H200 IonicContact OD1-ND1 2.69Å; H200-M204 HydrophobicContact CB-CE 3.86Å; H200-M204 WeakPolarHBondContact CD2-CE 3.34Å; H200-M204 VanDerWaalsContact CG-CE 3.47Å; H200-Y279 AromaticContact NE2-CZ 3.89Å; H200-Y279 PolarHBondContact NE2-OH 3.4Å
201I83.8Confident90Very high45 Ų4564 Ų6423%0.23130%0.297CS..  trans-111.3157.8171.254.5-176.5000110.2R147 L199 Y203 M204 I281 L290R147-I201 VanDerWaalsContact NH1-CG2 3.3Å; L199-I201 PolarHBondContact O-N 2.97Å; I201-Y203 PolarHBondContact O-N 3.34Å; I201-M204 HydrophobicContact CG1-CB 3.79Å; I201-M204 HydrophobicContact CG1-CG 4.4Å; I201-M204 HydrophobicContact CG1-SD 4.24Å; I201-M204 VanDerWaalsContact O-CB 3.29Å; I201-M204 WeakPolarHBondContact O-CB 3.18Å; I201-M204 PolarHBondContact O-N 3.15Å; I201-M204 VanDerWaalsContact O-N 3.15Å; I201-I281 HydrophobicContact CD1-CD1 3.7Å; I201-I281 HydrophobicContact CD1-CG1 3.89Å; I201-L290 HydrophobicContact CD1-CD1 4.49Å; I201-L290 HydrophobicContact CD1-CD2 4.45Å
202P81.1Confident90.1Very high95 Ų9567.6 Ų67.662%0.61731%0.311SS*.THydrogen-bonded Turntrans-49.2135.3172.2-28.236.2000111.2M204P202-M204 PolarHBondContact O-N 3.31Å
203Y85.6Confident90.2Very high172 Ų17269.8 Ų69.868%0.67533%0.325SS*.THydrogen-bonded Turntrans67.411.9177-34.3-76.3000116.4I201 K282I201-Y203 PolarHBondContact O-N 3.34Å; Y203-K282 WeakPolarHBondContact CB-O 3.36Å; Y203-K282 PolarHBondContact O-N 2.74Å
204M88.3Confident90.2Very high18 Ų1876 Ų769%0.08937%0.369CS..EExtended strand (participates in β ladder)trans-77.9129169.5-168.9-173.580.400110.4I194 H200 I201 P202 Y279 I280 L290I194-M204 HydrophobicContact CB-CE 4.35Å; I194-M204 HydrophobicContact CD1-CE 4.05Å; I194-M204 HydrophobicContact CD1-SD 3.59Å; I194-M204 VanDerWaalsContact CD1-SD 3.59Å; I194-M204 HydrophobicContact CG1-SD 4.49Å; I194-M204 HydrophobicContact CG2-CE 3.16Å; I194-M204 HydrophobicContact CG2-SD 3.84Å; H200-M204 HydrophobicContact CB-CE 3.86Å; H200-M204 WeakPolarHBondContact CD2-CE 3.34Å; H200-M204 VanDerWaalsContact CG-CE 3.47Å; I201-M204 HydrophobicContact CG1-CB 3.79Å; I201-M204 HydrophobicContact CG1-CG 4.4Å; I201-M204 HydrophobicContact CG1-SD 4.24Å; I201-M204 VanDerWaalsContact O-CB 3.29Å; I201-M204 WeakPolarHBondContact O-CB 3.18Å; I201-M204 PolarHBondContact O-N 3.15Å; I201-M204 VanDerWaalsContact O-N 3.15Å; P202-M204 PolarHBondContact O-N 3.31Å; M204-Y279 HydrophobicContact CE-CD1 3.5Å; M204-Y279 VanDerWaalsContact CE-CD1 3.5Å; M204-Y279 HydrophobicContact CE-CD2 4.41Å; M204-Y279 HydrophobicContact CE-CE1 3.47Å; M204-Y279 VanDerWaalsContact CE-CE1 3.47Å; M204-Y279 HydrophobicContact CE-CE2 4.35Å; M204-Y279 HydrophobicContact CE-CG 3.97Å; M204-Y279 HydrophobicContact CG-CD1 3.63Å; M204-Y279 HydrophobicContact CG-CE1 4.4Å; M204-Y279 HydrophobicContact CG-CG 4.07Å; M204-Y279 HydrophobicContact SD-CD1 3.98Å; M204-Y279 HydrophobicContact SD-CG 4.08Å; M204-I280 WeakPolarHBondContact CA-O 3.21Å; M204-L290 HydrophobicContact CG-CD2 3.75Å; M204-L290 HydrophobicContact SD-CD2 3.33Å; M204-L290 WeakPolarHBondContact SD-CD2 3.31Å
205V89.2Confident90.2Very high53 Ų5380.9 Ų80.932%0.32140%0.395SS..EExtended strand (participates in β ladder)trans-137.8149.7179.3-61.30000111.3N207 I280 K282V205-N207 PolarHBondContact O-N 3.38Å; V205-I280 HydrophobicContact CG2-CD1 4.09Å; V205-I280 HydrophobicContact CG2-CG1 3.72Å; V205-I280 PolarHBondContact N-O 2.92Å; V205-I280 WeakPolarHBondContact O-CG1 3.23Å; V205-I280 PolarHBondContact O-N 3.26Å; V205-K282 HydrophobicContact CG2-CD 3.83Å; V205-K282 HydrophobicContact CG2-CG 4.06Å
206R89.5Confident90.1Very high46 Ų4680.5 Ų80.517%0.17439%0.39CS..EExtended strand (participates in β ladder)trans-65.5133.1172-77.5-68.5-163.31792.5109.8N192 D195 Y208 R277 Y279N192-R206 PolarHBondContact ND2-NH1 2.96Å; D195-R206 IonicContact OD1-NH2 3.98Å; D195-R206 IonicContact OD2-CZ 2.67Å; D195-R206 IonicContact OD2-NE 3.72Å; D195-R206 IonicContact OD2-NH2 2.84Å; D195-R206 PolarHBondContact OD2-NH2 3.21Å; R206-Y208 HydrophobicContact CB-CD2 4.1Å; R206-Y208 HydrophobicContact CB-CE1 4.47Å; R206-Y208 HydrophobicContact CB-CE2 3.57Å; R206-Y208 VanDerWaalsContact O-CD2 3.28Å; R206-Y208 WeakPolarHBondContact O-CD2 3.48Å; R206-Y208 PolarHBondContact O-N 3.09Å; R206-Y208 VanDerWaalsContact O-N 3.15Å; R206-R277 PolarHBondContact NH1-O 2.89Å; R206-Y279 HydrophobicContact CB-CE1 4.44Å; R206-Y279 VanDerWaalsContact CD-CZ 3.5Å; R206-Y279 HydrophobicContact CG-CD1 4.2Å; R206-Y279 HydrophobicContact CG-CE1 3.61Å; R206-Y279 HydrophobicContact CG-CE2 4.44Å; R206-Y279 VanDerWaalsContact NE-CE2 3.29Å; R206-Y279 VanDerWaalsContact NE-CZ 3.29Å; R206-Y279 PolarHBondContact NE-OH 3.06Å
207N90.3Very high89.9Confident26 Ų2679.3 Ų79.314%0.13938%0.384CS..  trans-84.787.3174.8-172.1-9.2000111.1V205 K209 T210 P278 I280V205-N207 PolarHBondContact O-N 3.38Å; N207-K209 PolarHBondContact O-N 2.7Å; N207-K209 WeakPolarHBondContact OD1-CB 3.28Å; N207-K209 PolarHBondContact OD1-N 3.19Å; N207-T210 WeakPolarHBondContact CB-OG1 3.34Å; N207-T210 PolarHBondContact ND2-OG1 3.47Å; N207-T210 PolarHBondContact O-N 3.19Å; N207-T210 PolarHBondContact O-OG1 2.93Å; N207-T210 PolarHBondContact OD1-OG1 2.84Å; N207-P278 HydrophobicContact CB-CG 4.28Å; N207-P278 WeakPolarHBondContact CB-O 3.39Å; N207-P278 PolarHBondContact N-O 3.42Å; N207-I280 HydrophobicContact CB-CD1 4.04Å; N207-I280 HydrophobicContact CB-CG1 4.05Å; N207-I280 HydrophobicContact CB-CG2 3.85Å
208Y91.1Very high89.5Confident173 Ų17380.4 Ų80.468%0.67839%0.39SS*.THydrogen-bonded Turntrans-68.5-14.7179.6-68-80.7000114.6R206 T210 R277R206-Y208 HydrophobicContact CB-CD2 4.1Å; R206-Y208 HydrophobicContact CB-CE1 4.47Å; R206-Y208 HydrophobicContact CB-CE2 3.57Å; R206-Y208 VanDerWaalsContact O-CD2 3.28Å; R206-Y208 WeakPolarHBondContact O-CD2 3.48Å; R206-Y208 PolarHBondContact O-N 3.09Å; R206-Y208 VanDerWaalsContact O-N 3.15Å; Y208-T210 VanDerWaalsContact C-N 3.31Å; Y208-R277 PolarHBondContact O-NH1 2.81Å
209K90.1Very high89.2Confident175 Ų17580.1 Ų80.176%0.76138%0.382SS*.THydrogen-bonded Turntrans-75.6-23.7175.8-60.6177.4-179.1172.40112.1N207N207-K209 PolarHBondContact O-N 2.7Å; N207-K209 WeakPolarHBondContact OD1-CB 3.28Å; N207-K209 PolarHBondContact OD1-N 3.19Å
210T90.5Very high88.7Confident40 Ų4080.1 Ų80.125%0.24538%0.382CS..  trans-69.4138.6178.8-23.80000111.3N207 Y208 R277 P278N207-T210 WeakPolarHBondContact CB-OG1 3.34Å; N207-T210 PolarHBondContact ND2-OG1 3.47Å; N207-T210 PolarHBondContact O-N 3.19Å; N207-T210 PolarHBondContact O-OG1 2.93Å; N207-T210 PolarHBondContact OD1-OG1 2.84Å; Y208-T210 VanDerWaalsContact C-N 3.31Å; T210-R277 PolarHBondContact O-NH1 2.76Å; T210-P278 HydrophobicContact CG2-CG 4.03Å
211R93Very high88.7Confident217 Ų21776.4 Ų76.482%0.81937%0.365SS*.  trans-110.7158.4168.8-65.9-173.3174.4-142.5-0.8109.9P213 W275R211-P213 WeakPolarHBondContact O-CD 3.45Å; R211-W275 VanDerWaalsContact C-CZ2 3.48Å
212K92.9Very high88.7Confident84 Ų8476.1 Ų76.137%0.36536%0.364SS..  trans-59.9123.4172.4-177.6174.6175.2-170.40109.2W216 D218 W275K212-W216 WeakPolarHBondContact CE-O 3.32Å; K212-W216 HydrophobicContact CG-CB 4.06Å; K212-W216 PolarHBondContact NZ-O 2.81Å; K212-W216 VanDerWaalsContact NZ-O 3.14Å; K212-D218 WeakPolarHBondContact CE-OD2 3.35Å; K212-D218 VanDerWaalsContact NZ-CG 3.25Å; K212-D218 IonicContact NZ-OD1 2.77Å; K212-D218 IonicContact NZ-OD2 3.81Å; K212-D218 PolarHBondContact NZ-OD2 3.1Å; K212-W275 HydrophobicContact CB-CD2 3.61Å; K212-W275 HydrophobicContact CB-CE3 3.89Å; K212-W275 HydrophobicContact CB-CG 4.02Å; K212-W275 HydrophobicContact CB-CH2 4.24Å; K212-W275 HydrophobicContact CB-CZ2 4.03Å; K212-W275 HydrophobicContact CB-CZ3 4.19Å; K212-W275 HydrophobicContact CD-CB 3.95Å; K212-W275 HydrophobicContact CD-CD2 4.22Å; K212-W275 HydrophobicContact CD-CE3 4.37Å; K212-W275 HydrophobicContact CD-CG 4.04Å; K212-W275 HydrophobicContact CG-CB 4.02Å; K212-W275 HydrophobicContact CG-CD2 3.76Å; K212-W275 HydrophobicContact CG-CE3 4.27Å; K212-W275 HydrophobicContact CG-CG 3.61Å; K212-W275 VanDerWaalsContact N-CZ2 3.26Å
213P93.5Very high88.7Confident50 Ų5073.8 Ų73.833%0.32534%0.343SS..  trans-58.9144.2174.2-24.435.1000111.1R211 D215 W216R211-P213 WeakPolarHBondContact O-CD 3.45Å; P213-D215 WeakPolarHBondContact CB-OD1 3.31Å; P213-D215 PolarHBondContact O-N 3.36Å; P213-W216 HydrophobicContact CB-CB 4.24Å; P213-W216 HydrophobicContact CG-CE3 4.29Å; P213-W216 VanDerWaalsContact O-CB 3.32Å; P213-W216 WeakPolarHBondContact O-CB 3.06Å; P213-W216 PolarHBondContact O-N 3Å
214S92.9Very high88.7Confident133 Ų13367.8 Ų67.893%0.9332%0.322SS*.THydrogen-bonded Turntrans-66.4-26.6-178.551.30000113.3W216S214-W216 VanDerWaalsContact C-N 3.3Å
215D92.3Very high88.3Confident102 Ų10276.6 Ų76.655%0.54536%0.36SS..THydrogen-bonded Turntrans-83.4-3.1175.269.8-51.4000112.8P213 D217 R272P213-D215 WeakPolarHBondContact CB-OD1 3.31Å; P213-D215 PolarHBondContact O-N 3.36Å; D215-D217 PolarHBondContact O-N 2.95Å; D215-R272 VanDerWaalsContact CG-NH2 3.33Å; D215-R272 IonicContact OD1-NH2 3.47Å; D215-R272 PolarHBondContact OD1-NH2 2.82Å; D215-R272 IonicContact OD2-CZ 3.53Å; D215-R272 IonicContact OD2-NH1 3.75Å; D215-R272 PolarHBondContact OD2-NH1 2.95Å; D215-R272 IonicContact OD2-NH2 2.93Å; D215-R272 PolarHBondContact OD2-NH2 2.67Å
216W91.5Very high88Confident36 Ų3679.3 Ų79.314%0.13638%0.381CS..  trans-80.7112.2179.8-163.3-61.5000111.9N176 K212 P213 S214 D218 R272 G273 W275N176-W216 HydrophobicContact CB-CH2 3.8Å; N176-W216 WeakPolarHBondContact ND2-CH2 2.98Å; N176-W216 WeakPolarHBondContact ND2-CZ2 3.2Å; K212-W216 WeakPolarHBondContact CE-O 3.32Å; K212-W216 HydrophobicContact CG-CB 4.06Å; K212-W216 PolarHBondContact NZ-O 2.81Å; K212-W216 VanDerWaalsContact NZ-O 3.14Å; P213-W216 HydrophobicContact CB-CB 4.24Å; P213-W216 HydrophobicContact CG-CE3 4.29Å; P213-W216 VanDerWaalsContact O-CB 3.32Å; P213-W216 WeakPolarHBondContact O-CB 3.06Å; P213-W216 PolarHBondContact O-N 3Å; S214-W216 VanDerWaalsContact C-N 3.3Å; W216-D218 PolarHBondContact NE1-OD1 2.81Å; W216-R272 HydrophobicContact CD2-CG 4.34Å; W216-R272 VanDerWaalsContact CE3-NH2 3.35Å; W216-R272 HydrophobicContact CH2-CG 3.88Å; W216-R272 HydrophobicContact CZ2-CG 3.69Å; W216-R272 HydrophobicContact CZ3-CG 4.31Å; W216-G273 VanDerWaalsContact CZ2-O 3.29Å; W216-G273 WeakPolarHBondContact CZ2-O 3.1Å; W216-G273 PolarHBondContact NE1-O 2.81Å; W216-W275 HydrophobicContact CD2-CB 4.03Å; W216-W275 AromaticContact CD2-CD1 3.72Å; W216-W275 HydrophobicContact CD2-CG 4.28Å; W216-W275 AromaticContact CE3-CD1 3.85Å; W216-W275 HydrophobicContact CG-CB 3.92Å; W216-W275 HydrophobicContact CG-CG 4.33Å
217D89.9Confident87.2Confident24 Ų2478.1 Ų78.113%0.12838%0.381CS..  trans-101.8115.9178.5-162.2-11.1000112.2D215 R219 N268D215-D217 PolarHBondContact O-N 2.95Å; D217-R219 VanDerWaalsContact CG-NE 3.28Å; D217-R219 VanDerWaalsContact OD1-CB 3.23Å; D217-R219 WeakPolarHBondContact OD1-CB 3.43Å; D217-R219 VanDerWaalsContact OD1-CG 3.27Å; D217-R219 WeakPolarHBondContact OD1-CG 3.12Å; D217-R219 IonicContact OD1-CZ 3.65Å; D217-R219 PolarHBondContact OD1-N 2.92Å; D217-R219 IonicContact OD1-NE 3.87Å; D217-R219 PolarHBondContact OD1-NE 2.78Å; D217-R219 IonicContact OD1-NH2 2.7Å; D217-R219 IonicContact OD2-CZ 2.77Å; D217-R219 VanDerWaalsContact OD2-CZ 3.3Å; D217-R219 IonicContact OD2-NE 3.36Å; D217-R219 PolarHBondContact OD2-NE 3.47Å; D217-R219 VanDerWaalsContact OD2-NE 3.11Å; D217-R219 IonicContact OD2-NH2 3.69Å; D217-R219 PolarHBondContact OD2-NH2 2.82Å; D217-N268 WeakPolarHBondContact CB-ND2 3.39Å; D217-N268 PolarHBondContact OD2-ND2 3.43Å
218D86.3Confident86.2Confident27 Ų2782.4 Ų82.414%0.14441%0.41CS..  trans-90.2-1.7178.2-67.9-29.7000112.6K212 W216 W275K212-D218 WeakPolarHBondContact CE-OD2 3.35Å; K212-D218 VanDerWaalsContact NZ-CG 3.25Å; K212-D218 IonicContact NZ-OD1 2.77Å; K212-D218 IonicContact NZ-OD2 3.81Å; K212-D218 PolarHBondContact NZ-OD2 3.1Å; W216-D218 PolarHBondContact NE1-OD1 2.81Å; D218-W275 PolarHBondContact OD1-N 2.82Å
219R84.8Confident85Confident84 Ų8480 Ų8032%0.31741%0.409SS..BIsolated β-bridgetrans-76.1125.7180-61.2169.6-72-1778.4109.1D217 L222 D239 K241 N268D217-R219 VanDerWaalsContact CG-NE 3.28Å; D217-R219 VanDerWaalsContact OD1-CB 3.23Å; D217-R219 WeakPolarHBondContact OD1-CB 3.43Å; D217-R219 VanDerWaalsContact OD1-CG 3.27Å; D217-R219 WeakPolarHBondContact OD1-CG 3.12Å; D217-R219 IonicContact OD1-CZ 3.65Å; D217-R219 PolarHBondContact OD1-N 2.92Å; D217-R219 IonicContact OD1-NE 3.87Å; D217-R219 PolarHBondContact OD1-NE 2.78Å; D217-R219 IonicContact OD1-NH2 2.7Å; D217-R219 IonicContact OD2-CZ 2.77Å; D217-R219 VanDerWaalsContact OD2-CZ 3.3Å; D217-R219 IonicContact OD2-NE 3.36Å; D217-R219 PolarHBondContact OD2-NE 3.47Å; D217-R219 VanDerWaalsContact OD2-NE 3.11Å; D217-R219 IonicContact OD2-NH2 3.69Å; D217-R219 PolarHBondContact OD2-NH2 2.82Å; R219-L222 HydrophobicContact CB-CD2 3.84Å; R219-L222 HydrophobicContact CG-CD2 4.42Å; R219-L222 VanDerWaalsContact CZ-CD2 3.48Å; R219-D239 HydrophobicContact CB-CB 4.42Å; R219-D239 VanDerWaalsContact CD-CG 3.48Å; R219-D239 VanDerWaalsContact CD-OD2 3.23Å; R219-D239 WeakPolarHBondContact CD-OD2 3.27Å; R219-D239 HydrophobicContact CG-CB 3.83Å; R219-D239 IonicContact CZ-OD2 3.54Å; R219-D239 IonicContact NE-OD2 3.34Å; R219-D239 IonicContact NH1-OD2 3.97Å; R219-D239 PolarHBondContact NH1-OD2 2.89Å; R219-K241 HydrophobicContact CG-CG 4.36Å; R219-N268 WeakPolarHBondContact O-CB 3.47Å; R219-N268 PolarHBondContact O-ND2 3.44Å
220I81.7Confident83.4Confident2 Ų276 Ų761%0.0140%0.396CS..SBendtrans-75.2-41.1174-62.7168.2000109.7I240 F242 M245 N268 Y271I220-I240 PolarHBondContact N-O 2.89Å; I220-F242 HydrophobicContact CD1-CB 4.26Å; I220-F242 HydrophobicContact CD1-CD2 3.71Å; I220-F242 HydrophobicContact CD1-CE2 4.43Å; I220-F242 HydrophobicContact CD1-CG 4.35Å; I220-F242 HydrophobicContact CG1-CD2 4.45Å; I220-M245 HydrophobicContact CB-CE 3.87Å; I220-M245 HydrophobicContact CD1-CE 3.77Å; I220-M245 HydrophobicContact CD1-SD 3.77Å; I220-M245 HydrophobicContact CG1-CE 4.41Å; I220-M245 HydrophobicContact CG2-CE 4.05Å; I220-N268 WeakPolarHBondContact O-CB 3.42Å; I220-N268 PolarHBondContact O-N 3.15Å; I220-Y271 HydrophobicContact CG1-CE2 4.2Å
221F83.6Confident81.3Confident3 Ų381.9 Ų81.91%0.01343%0.426CS..EExtended strand (participates in β ladder)trans-120.9142.7177.1-58.9-63.3000110.5I240 M245 G259 A261 Y265 I266 R267F221-I240 HydrophobicContact CB-CB 4.45Å; F221-M245 HydrophobicContact CD2-CE 3.22Å; F221-M245 HydrophobicContact CE2-CE 3.24Å; F221-M245 HydrophobicContact CE2-SD 4.39Å; F221-M245 HydrophobicContact CG-CE 4.43Å; F221-M245 HydrophobicContact CZ-CE 4.44Å; F221-G259 WeakPolarHBondContact CZ-O 3.07Å; F221-A261 HydrophobicContact CD1-CB 3.51Å; F221-A261 HydrophobicContact CE1-CB 3.58Å; F221-A261 HydrophobicContact CG-CB 4.28Å; F221-A261 HydrophobicContact CZ-CB 4.35Å; F221-Y265 HydrophobicContact CB-CD1 4.44Å; F221-I266 CarbonylContact C-O 3.42Å; F221-I266 WeakPolarHBondContact CA-O 3.29Å; F221-R267 HydrophobicContact CD1-CB 4.13Å; F221-R267 HydrophobicContact CD1-CG 4.41Å; F221-R267 HydrophobicContact CE1-CB 4.12Å; F221-R267 HydrophobicContact CE1-CG 4.22Å
222L84.1Confident79.2Confident39 Ų3975.2 Ų75.220%0.20442%0.424CS..EExtended strand (participates in β ladder)trans-110.7147.4174.2-58.3176.7000108.9R219 N224 Y265 I266 N268R219-L222 HydrophobicContact CB-CD2 3.84Å; R219-L222 HydrophobicContact CG-CD2 4.42Å; R219-L222 VanDerWaalsContact CZ-CD2 3.48Å; L222-N224 PolarHBondContact O-N 2.93Å; L222-Y265 CarbonylContact O-C 3.43Å; L222-Y265 VanDerWaalsContact O-CA 3.3Å; L222-Y265 WeakPolarHBondContact O-CA 3.47Å; L222-I266 HydrophobicContact CB-CG1 4.37Å; L222-I266 PolarHBondContact N-O 3.47Å; L222-I266 PolarHBondContact O-N 3.04Å; L222-N268 HydrophobicContact CD1-CB 4.12Å; L222-N268 HydrophobicContact CD2-CB 4.46Å; L222-N268 HydrophobicContact CG-CB 3.91Å
223R82.1Confident77.1Confident46 Ų4677.9 Ų77.917%0.17444%0.436CS..EExtended strand (participates in β ladder)trans-57.5128.5172.3-176.367.3-168.9-80.6-7.1110.6K225 D239 G264 Y265R223-K225 PolarHBondContact O-N 3.35Å; R223-D239 PolarHBondContact N-OD1 3.09Å; R223-G264 WeakPolarHBondContact CD-O 3.47Å; R223-G264 PolarHBondContact NE-O 2.77Å; R223-Y265 HydrophobicContact CB-CD1 4.44Å; R223-Y265 HydrophobicContact CB-CE1 4.29Å
224N84.1Confident74.7Confident46 Ų4680.6 Ų80.625%0.24646%0.456CS..  trans-76.1104.1170.8-173.6-6.3000109.1L222 S226 A227 G264 I266L222-N224 PolarHBondContact O-N 2.93Å; N224-S226 PolarHBondContact O-N 3.33Å; N224-S226 VanDerWaalsContact O-N 3.12Å; N224-S226 WeakPolarHBondContact OD1-CB 3.25Å; N224-S226 PolarHBondContact OD1-N 2.69Å; N224-A227 HydrophobicContact CB-CB 3.99Å; N224-A227 WeakPolarHBondContact O-CB 3.25Å; N224-A227 PolarHBondContact O-N 2.74Å; N224-G264 WeakPolarHBondContact CA-O 3.35Å; N224-G264 VanDerWaalsContact CB-O 3.24Å; N224-G264 WeakPolarHBondContact CB-O 3.12Å; N224-G264 PolarHBondContact N-O 2.98Å; N224-I266 HydrophobicContact CB-CG1 4.44Å; N224-I266 HydrophobicContact CB-CG2 3.97Å
225K81.7Confident72.6Confident202 Ų20280.4 Ų80.488%0.87844%0.436SS*.THydrogen-bonded Turntrans-62.4-17.9179.7-63.5-174.8178.5-176.30113.9R223R223-K225 PolarHBondContact O-N 3.35Å
226S81.7Confident70.6Confident111 Ų11179.7 Ų79.778%0.77644%0.435SS*.THydrogen-bonded Turntrans-91.3-8.8177.9-48.20000113N224N224-S226 PolarHBondContact O-N 3.33Å; N224-S226 VanDerWaalsContact O-N 3.12Å; N224-S226 WeakPolarHBondContact OD1-CB 3.25Å; N224-S226 PolarHBondContact OD1-N 2.69Å
227A74Confident68.8Low20 Ų2085.8 Ų85.817%0.16547%0.465CS..SBendtrans-80.5137.1178.500000110.4N224 L229N224-A227 HydrophobicContact CB-CB 3.99Å; N224-A227 WeakPolarHBondContact O-CB 3.25Å; N224-A227 PolarHBondContact O-N 2.74Å; A227-L229 PolarHBondContact O-N 3.26Å
228P69Low67.3Low116 Ų11691.5 Ų91.575%0.75349%0.491SS*.  trans-52.6136.6174.3-21.830.7000110.7D230P228-D230 PolarHBondContact O-N 3.28Å; P228-D230 VanDerWaalsContact O-N 3.15Å
229L64.5Low66.4Low124 Ų12492 Ų9265%0.64949%0.494SS*.  trans-66.1109.9163.6-73.5155.8000106.1A227A227-L229 PolarHBondContact O-N 3.26Å
230D56.6Low65.6Low91 Ų9189.2 Ų89.249%0.48749%0.485SS..  trans-60140.8-179.5-171.220.4000110.9P228 G232P228-D230 PolarHBondContact O-N 3.28Å; P228-D230 VanDerWaalsContact O-N 3.15Å; D230-G232 VanDerWaalsContact C-N 3.32Å; D230-G232 PolarHBondContact O-N 2.81Å
231N46Very low65.1Low163 Ų16394.8 Ų94.887%0.87251%0.509SS*.THydrogen-bonded Turntrans-69.172.9-162.3-64.5-22.3000113.3
232G48.8Very low64.4Low77 Ų7795.3 Ų95.379%0.79451%0.511SS*.THydrogen-bonded Turntrans114.2-2.9168.900000115.8D230 S234D230-G232 VanDerWaalsContact C-N 3.32Å; D230-G232 PolarHBondContact O-N 2.81Å; G232-S234 PolarHBondContact O-N 2.85Å
233K49.2Very low63.7Low139 Ų13996.5 Ų96.560%0.60452%0.516SS*.  trans-91.296.9162.2-71.5-176.8-177.1174.40108.1Y235K233-Y235 HydrophobicContact CB-CD2 4.1Å; K233-Y235 HydrophobicContact CB-CE2 3.92Å; K233-Y235 HydrophobicContact CD-CE2 4.25Å; K233-Y235 PolarHBondContact O-N 3.04Å
234S44.2Very low62.9Low107 Ų10798.2 Ų98.275%0.74853%0.531SS*.  trans-62.380.51611650000108G232 V236G232-S234 PolarHBondContact O-N 2.85Å; S234-V236 VanDerWaalsContact C-N 3.28Å; S234-V236 PolarHBondContact O-N 2.8Å
235Y47.9Very low61.9Low130 Ų13097.6 Ų97.651%0.5153%0.527SS..  trans-60108.2149.5-72.1-86.2000103.7K233 E237K233-Y235 HydrophobicContact CB-CD2 4.1Å; K233-Y235 HydrophobicContact CB-CE2 3.92Å; K233-Y235 HydrophobicContact CD-CE2 4.25Å; K233-Y235 PolarHBondContact O-N 3.04Å; Y235-E237 PolarHBondContact O-N 3.2Å
236V51.2Low60.9Low86 Ų8693 Ų9352%0.52151%0.505SS..  trans-43.5136.1174.4-164.70000106.2S234 E238S234-V236 VanDerWaalsContact C-N 3.28Å; S234-V236 PolarHBondContact O-N 2.8Å; V236-E238 HydrophobicContact CB-CB 4.35Å; V236-E238 HydrophobicContact CB-CG 4.31Å; V236-E238 HydrophobicContact CG1-CB 4.27Å; V236-E238 HydrophobicContact CG1-CG 3.7Å; V236-E238 PolarHBondContact O-N 2.89Å
237E52.4Low59.5Low164 Ų16493.5 Ų93.577%0.76650%0.499SS*.SBendtrans-62.825.1177.6-121.7178.4-167.700112.8Y235Y235-E237 PolarHBondContact O-N 3.2Å
238E60.2Low58.2Low144 Ų14494.6 Ų94.667%0.67351%0.505SS*.  trans-86.9110.6176.5-75.4179-173.600108.3V236V236-E238 HydrophobicContact CB-CB 4.35Å; V236-E238 HydrophobicContact CB-CG 4.31Å; V236-E238 HydrophobicContact CG1-CB 4.27Å; V236-E238 HydrophobicContact CG1-CG 3.7Å; V236-E238 PolarHBondContact O-N 2.89Å
239D67.4Low56.8Low39 Ų3999.3 Ų99.321%0.20951%0.514CS..  trans-53.6147.5168.7-61.8-62.8000111.6R219 R223 K241R219-D239 HydrophobicContact CB-CB 4.42Å; R219-D239 VanDerWaalsContact CD-CG 3.48Å; R219-D239 VanDerWaalsContact CD-OD2 3.23Å; R219-D239 WeakPolarHBondContact CD-OD2 3.27Å; R219-D239 HydrophobicContact CG-CB 3.83Å; R219-D239 IonicContact CZ-OD2 3.54Å; R219-D239 IonicContact NE-OD2 3.34Å; R219-D239 IonicContact NH1-OD2 3.97Å; R219-D239 PolarHBondContact NH1-OD2 2.89Å; R223-D239 PolarHBondContact N-OD1 3.09Å; D239-K241 PolarHBondContact O-N 2.89Å; D239-K241 VanDerWaalsContact O-N 3.15Å
240I68.1Low55.6Low25 Ų25100.5 Ų100.513%0.12852%0.516CS..  trans-78.4108.2-175.5-54177000109.3I220 F221 M245 P262 Y265I220-I240 PolarHBondContact N-O 2.89Å; F221-I240 HydrophobicContact CB-CB 4.45Å; I240-M245 HydrophobicContact CG2-CE 3.59Å; I240-M245 HydrophobicContact CG2-CG 4.03Å; I240-P262 HydrophobicContact CD1-CB 4.17Å; I240-P262 HydrophobicContact CD1-CG 3.55Å; I240-Y265 HydrophobicContact CD1-CD1 4.06Å; I240-Y265 HydrophobicContact CD1-CD2 4.19Å; I240-Y265 HydrophobicContact CD1-CE1 4.04Å; I240-Y265 HydrophobicContact CD1-CE2 4.16Å; I240-Y265 HydrophobicContact CD1-CG 4.15Å; I240-Y265 HydrophobicContact CG1-CD1 4.14Å; I240-Y265 HydrophobicContact CG1-CE1 3.83Å
241K70.2Confident54.6Low119 Ų119107.6 Ų107.652%0.51754%0.536SS..BIsolated β-bridgetrans-82.6157.8174.2-64.6178.2-175.71700111R219 D239 E243 T244R219-K241 HydrophobicContact CG-CG 4.36Å; D239-K241 PolarHBondContact O-N 2.89Å; D239-K241 VanDerWaalsContact O-N 3.15Å; K241-E243 VanDerWaalsContact C-N 3.26Å; K241-E243 PolarHBondContact O-N 3.19Å; K241-T244 PolarHBondContact O-N 3.26Å; K241-T244 PolarHBondContact O-OG1 3.04Å
242F68.4Low54.3Low14 Ų14105.5 Ų105.56%0.06152%0.517CS..Hα-helixtrans-52-44.7175.9-174.2-77.3000112.7V187 A190 I220 T244 M245 Y246V187-F242 HydrophobicContact CB-CE2 4.05Å; V187-F242 HydrophobicContact CB-CZ 4.1Å; V187-F242 HydrophobicContact CG1-CE2 3.6Å; V187-F242 HydrophobicContact CG1-CZ 3.41Å; V187-F242 VanDerWaalsContact CG1-CZ 3.41Å; V187-F242 HydrophobicContact CG2-CE2 3.9Å; V187-F242 HydrophobicContact CG2-CZ 4.45Å; A190-F242 HydrophobicContact CB-CE1 3.98Å; A190-F242 HydrophobicContact CB-CE2 3.61Å; A190-F242 HydrophobicContact CB-CZ 3.19Å; I220-F242 HydrophobicContact CD1-CB 4.26Å; I220-F242 HydrophobicContact CD1-CD2 3.71Å; I220-F242 HydrophobicContact CD1-CE2 4.43Å; I220-F242 HydrophobicContact CD1-CG 4.35Å; I220-F242 HydrophobicContact CG1-CD2 4.45Å; F242-T244 VanDerWaalsContact C-N 3.27Å; F242-T244 PolarHBondContact O-N 3.45Å; F242-M245 PolarHBondContact O-N 3.4Å; F242-M245 VanDerWaalsContact O-N 3.16Å; F242-Y246 PolarHBondContact O-N 3.45Å
243E69.1Low53.7Low64 Ų64106.8 Ų106.830%0.29951%0.506SS..Hα-helixtrans-62.6-31.2-175.1-7080178.900113.4K241 N247 R274K241-E243 VanDerWaalsContact C-N 3.26Å; K241-E243 PolarHBondContact O-N 3.19Å; E243-N247 WeakPolarHBondContact O-CB 3.37Å; E243-N247 PolarHBondContact O-N 3.35Å; E243-N247 VanDerWaalsContact O-N 3.15Å; E243-R274 IonicContact OE1-CZ 3.66Å; E243-R274 IonicContact OE1-NE 3.95Å; E243-R274 PolarHBondContact OE1-NE 3.05Å; E243-R274 IonicContact OE1-NH2 3.57Å; E243-R274 PolarHBondContact OE1-NH2 2.96Å
244T65.6Low53.2Low81 Ų81109.9 Ų109.950%0.49752%0.522SS..Hα-helixtrans-73.7-29.2179.658.50000111.8K241 F242 S248K241-T244 PolarHBondContact O-N 3.26Å; K241-T244 PolarHBondContact O-OG1 3.04Å; F242-T244 VanDerWaalsContact C-N 3.27Å; F242-T244 PolarHBondContact O-N 3.45Å; T244-S248 WeakPolarHBondContact O-CB 3.48Å
245M64.1Low52.8Low33 Ų33110 Ų11016%0.16352%0.519CS..Hα-helixtrans-72.8-33.2174.6-66.7-169.3-161.300113.4I220 F221 I240 F242I220-M245 HydrophobicContact CB-CE 3.87Å; I220-M245 HydrophobicContact CD1-CE 3.77Å; I220-M245 HydrophobicContact CD1-SD 3.77Å; I220-M245 HydrophobicContact CG1-CE 4.41Å; I220-M245 HydrophobicContact CG2-CE 4.05Å; F221-M245 HydrophobicContact CD2-CE 3.22Å; F221-M245 HydrophobicContact CE2-CE 3.24Å; F221-M245 HydrophobicContact CE2-SD 4.39Å; F221-M245 HydrophobicContact CG-CE 4.43Å; F221-M245 HydrophobicContact CZ-CE 4.44Å; I240-M245 HydrophobicContact CG2-CE 3.59Å; I240-M245 HydrophobicContact CG2-CG 4.03Å; F242-M245 PolarHBondContact O-N 3.4Å; F242-M245 VanDerWaalsContact O-N 3.16Å
246Y59.5Low52.7Low107 Ų107109.6 Ų109.642%0.4252%0.521SS..Hα-helixtrans-83.3-37-177.4-172.2-91.1000112.6K156 F242K156-Y246 PolarHBondContact NZ-OH 3.45Å; K156-Y246 VanDerWaalsContact NZ-OH 3.14Å; F242-Y246 PolarHBondContact O-N 3.45Å
247N52.5Low52.5Low120 Ų120107 Ų10764%0.64250%0.503SS*.Hα-helixtrans-93.70.3-173.4-80.1-22.8000114.9E243 K249E243-N247 WeakPolarHBondContact O-CB 3.37Å; E243-N247 PolarHBondContact O-N 3.35Å; E243-N247 VanDerWaalsContact O-N 3.15Å; N247-K249 PolarHBondContact O-N 3.34Å
248S46.5Very low52.5Low43 Ų43101.3 Ų101.330%0.30148%0.479SS..  trans-70.499.8-175.665.90000111.3T244 H250T244-S248 WeakPolarHBondContact O-CB 3.48Å; S248-H250 PolarHBondContact O-N 3.41Å
249K40Very low52.3Low215 Ų21594.5 Ų94.594%0.93545%0.448SS*.  trans-53.6-3.4146.7-107.9-178178.5179.30112.9N247N247-K249 PolarHBondContact O-N 3.34Å
250H39.5Very low52.3Low149 Ų149100.8 Ų100.869%0.6947%0.468SS*.SBendtrans-79.8122.4174.8-61.4-76.6000109.6S248 Y252S248-H250 PolarHBondContact O-N 3.41Å; H250-Y252 PolarHBondContact O-N 2.7Å
251R35.8Very low52.6Low241 Ų241100.5 Ų100.591%0.90947%0.47SS*.  trans-49.975.1162.8-63.5172.9-179.3144.2-3.1110.8D253R251-D253 PolarHBondContact O-N 2.99Å
252Y39.5Very low52.8Low118 Ų11896.8 Ų96.846%0.46346%0.458SS..  trans-73.3103.7141.3-75.8-81000103.1H250 E254H250-Y252 PolarHBondContact O-N 2.7Å; Y252-E254 PolarHBondContact O-N 3.16Å
253D36.3Very low53.1Low105 Ų105104.9 Ų104.956%0.56150%0.496SS*.  trans-46.1138.1-179.4-149.919.2000107.5R251 T255 E256R251-D253 PolarHBondContact O-N 2.99Å; D253-T255 VanDerWaalsContact CB-OG1 3.26Å; D253-T255 WeakPolarHBondContact CB-OG1 3.46Å; D253-T255 VanDerWaalsContact CG-OG1 3.32Å; D253-T255 PolarHBondContact O-N 3.37Å; D253-T255 PolarHBondContact OD2-OG1 2.66Å; D253-T255 VanDerWaalsContact OD2-OG1 3.07Å; D253-E256 PolarHBondContact O-N 2.93Å
254E38.8Very low53.5Low204 Ų204102.7 Ų102.795%0.95349%0.49SS*.THydrogen-bonded Turntrans-56.1-9.3179.9-72.9176.1163.200112.7Y252Y252-E254 PolarHBondContact O-N 3.16Å
255T36.5Very low54.3Low110 Ų110100 Ų10068%0.67547%0.471SS*.THydrogen-bonded Turntrans-79.8-19.7174.258.20000114.4D253D253-T255 VanDerWaalsContact CB-OG1 3.26Å; D253-T255 WeakPolarHBondContact CB-OG1 3.46Å; D253-T255 VanDerWaalsContact CG-OG1 3.32Å; D253-T255 PolarHBondContact O-N 3.37Å; D253-T255 PolarHBondContact OD2-OG1 2.66Å; D253-T255 VanDerWaalsContact OD2-OG1 3.07Å
256E44.6Very low55.3Low120 Ų120102.3 Ų102.356%0.56148%0.484SS*.SBendtrans-99.7117.1178.2-81.9-171.9164.200111.5D253 V258D253-E256 PolarHBondContact O-N 2.93Å; E256-V258 WeakPolarHBondContact O-CG2 3.48Å; E256-V258 PolarHBondContact O-N 3.36Å
257F47.5Very low56.4Low33 Ų3398.9 Ų98.915%0.14547%0.47CS..  trans-61.599.3175.5173.7-117.1000112.1D184 N185 G259 R260 D329 E330 F333 M334D184-F257 WeakPolarHBondContact O-CD2 3.48Å; D184-F257 WeakPolarHBondContact O-CE2 3.35Å; N185-F257 HydrophobicContact CB-CE2 3.7Å; N185-F257 HydrophobicContact CB-CZ 3.57Å; F257-G259 PolarHBondContact O-N 3.34Å; F257-R260 HydrophobicContact CD1-CB 3.21Å; F257-R260 HydrophobicContact CD1-CG 4.49Å; F257-R260 HydrophobicContact CE1-CB 3.54Å; F257-R260 HydrophobicContact CG-CB 4.37Å; F257-R260 PolarHBondContact O-N 2.93Å; F257-R260 VanDerWaalsContact O-N 3.09Å; F257-D329 HydrophobicContact CZ-CB 4.46Å; F257-E330 HydrophobicContact CE1-CG 4.19Å; F257-F333 HydrophobicContact CE2-CD1 4.43Å; F257-M334 HydrophobicContact CB-CE 3.18Å; F257-M334 HydrophobicContact CB-CG 4.29Å; F257-M334 HydrophobicContact CB-SD 3.55Å; F257-M334 VanDerWaalsContact CB-SD 3.55Å; F257-M334 HydrophobicContact CD1-CE 4.09Å; F257-M334 HydrophobicContact CD1-CG 3.44Å; F257-M334 VanDerWaalsContact CD1-CG 3.44Å; F257-M334 HydrophobicContact CD1-SD 3.78Å; F257-M334 HydrophobicContact CD2-CE 3.93Å; F257-M334 HydrophobicContact CD2-CG 3.62Å; F257-M334 HydrophobicContact CD2-SD 2.98Å; F257-M334 WeakPolarHBondContact CD2-SD 3.24Å; F257-M334 HydrophobicContact CE1-CG 3.39Å; F257-M334 HydrophobicContact CE1-SD 4.15Å; F257-M334 HydrophobicContact CE2-CG 3.46Å; F257-M334 VanDerWaalsContact CE2-CG 3.46Å; F257-M334 HydrophobicContact CE2-SD 3.32Å; F257-M334 WeakPolarHBondContact CE2-SD 3.33Å; F257-M334 HydrophobicContact CG-CE 3.55Å; F257-M334 HydrophobicContact CG-CG 3.58Å; F257-M334 HydrophobicContact CG-SD 3.2Å; F257-M334 WeakPolarHBondContact CG-SD 3.12Å; F257-M334 HydrophobicContact CZ-CG 3.36Å; F257-M334 HydrophobicContact CZ-SD 3.92Å
258V51.9Low58.1Low43 Ų4393.4 Ų93.426%0.26144%0.44SS..THydrogen-bonded Turntrans-61.1-16.6178.9-165.60000112.1R186 E256R186-V258 HydrophobicContact CB-CB 4.28Å; R186-V258 HydrophobicContact CG-CB 3.95Å; R186-V258 HydrophobicContact CG-CG1 4.22Å; R186-V258 HydrophobicContact CG-CG2 4.43Å; E256-V258 WeakPolarHBondContact O-CG2 3.48Å; E256-V258 PolarHBondContact O-N 3.36Å
259G56.3Low60.1Low1 Ų1101.1 Ų101.11%0.0146%0.463CS..THydrogen-bonded Turntrans-76.9-24.8175.700000114.8N185 F221 F257 R267N185-G259 PolarHBondContact ND2-O 3.06Å; N185-G259 WeakPolarHBondContact O-CA 3.5Å; F221-G259 WeakPolarHBondContact CZ-O 3.07Å; F257-G259 PolarHBondContact O-N 3.34Å; G259-R267 PolarHBondContact O-NH2 3.02Å
260R68.2Low62.4Low171 Ų17196.9 Ų96.965%0.64545%0.451SS*.SBendtrans-82.4145.6177.8174.4176.2-168.8-178.85.4109.7F257 P262F257-R260 HydrophobicContact CD1-CB 3.21Å; F257-R260 HydrophobicContact CD1-CG 4.49Å; F257-R260 HydrophobicContact CE1-CB 3.54Å; F257-R260 HydrophobicContact CG-CB 4.37Å; F257-R260 PolarHBondContact O-N 2.93Å; F257-R260 VanDerWaalsContact O-N 3.09Å; R260-P262 VanDerWaalsContact O-CD 3.31Å; R260-P262 WeakPolarHBondContact O-CD 3.47Å; R260-P262 VanDerWaalsContact O-N 3.17Å
261A73.6Confident64.7Low19 Ų1990.4 Ų90.416%0.15742%0.42CS..PPolyproline II helixtrans-54.4123.917100000109.3F221 Y265F221-A261 HydrophobicContact CD1-CB 3.51Å; F221-A261 HydrophobicContact CE1-CB 3.58Å; F221-A261 HydrophobicContact CG-CB 4.28Å; F221-A261 HydrophobicContact CZ-CB 4.35Å; A261-Y265 WeakPolarHBondContact CB-O 3.27Å
262P74Confident67.1Low41 Ų4183.3 Ų83.327%0.26639%0.393SS..PPolyproline II helixtrans-56.3158.2176.6-29.639.7000111.2I240 R260 G264 Y265I240-P262 HydrophobicContact CD1-CB 4.17Å; I240-P262 HydrophobicContact CD1-CG 3.55Å; R260-P262 VanDerWaalsContact O-CD 3.31Å; R260-P262 WeakPolarHBondContact O-CD 3.47Å; R260-P262 VanDerWaalsContact O-N 3.17Å; P262-G264 PolarHBondContact O-N 3.19Å; P262-Y265 HydrophobicContact CB-CD2 3.9Å; P262-Y265 HydrophobicContact CB-CE2 4.49Å; P262-Y265 WeakPolarHBondContact O-CB 3.25Å; P262-Y265 PolarHBondContact O-N 3.47Å
263Q75Confident69.3Low184 Ų18477.7 Ų77.786%0.8637%0.371SS*.THydrogen-bonded Turntrans-53128-179.4-174.9175.8-3.900110.8Y265Q263-Y265 WeakPolarHBondContact O-CD2 3.47Å
264G77.7Confident71.8Confident18 Ų1876.9 Ų76.919%0.18636%0.361CS..THydrogen-bonded Turntrans82.29.7-177.100000115.2R223 N224 P262R223-G264 WeakPolarHBondContact CD-O 3.47Å; R223-G264 PolarHBondContact NE-O 2.77Å; N224-G264 WeakPolarHBondContact CA-O 3.35Å; N224-G264 VanDerWaalsContact CB-O 3.24Å; N224-G264 WeakPolarHBondContact CB-O 3.12Å; N224-G264 PolarHBondContact N-O 2.98Å; P262-G264 PolarHBondContact O-N 3.19Å
265Y82.5Confident74.2Confident25 Ų2569.7 Ų69.710%0.09833%0.325CS..EExtended strand (participates in β ladder)trans-117.8160172.6-64.7-97.9000111.5F221 L222 R223 I240 A261 P262 Q263F221-Y265 HydrophobicContact CB-CD1 4.44Å; L222-Y265 CarbonylContact O-C 3.43Å; L222-Y265 VanDerWaalsContact O-CA 3.3Å; L222-Y265 WeakPolarHBondContact O-CA 3.47Å; R223-Y265 HydrophobicContact CB-CD1 4.44Å; R223-Y265 HydrophobicContact CB-CE1 4.29Å; I240-Y265 HydrophobicContact CD1-CD1 4.06Å; I240-Y265 HydrophobicContact CD1-CD2 4.19Å; I240-Y265 HydrophobicContact CD1-CE1 4.04Å; I240-Y265 HydrophobicContact CD1-CE2 4.16Å; I240-Y265 HydrophobicContact CD1-CG 4.15Å; I240-Y265 HydrophobicContact CG1-CD1 4.14Å; I240-Y265 HydrophobicContact CG1-CE1 3.83Å; A261-Y265 WeakPolarHBondContact CB-O 3.27Å; P262-Y265 HydrophobicContact CB-CD2 3.9Å; P262-Y265 HydrophobicContact CB-CE2 4.49Å; P262-Y265 WeakPolarHBondContact O-CB 3.25Å; P262-Y265 PolarHBondContact O-N 3.47Å; Q263-Y265 WeakPolarHBondContact O-CD2 3.47Å
266I84.2Confident76.7Confident82 Ų8266 Ų6642%0.42130%0.3SS..EExtended strand (participates in β ladder)trans-130151.4172.750.5169.3000109.7F221 L222 N224F221-I266 CarbonylContact C-O 3.42Å; F221-I266 WeakPolarHBondContact CA-O 3.29Å; L222-I266 HydrophobicContact CB-CG1 4.37Å; L222-I266 PolarHBondContact N-O 3.47Å; L222-I266 PolarHBondContact O-N 3.04Å; N224-I266 HydrophobicContact CB-CG1 4.44Å; N224-I266 HydrophobicContact CB-CG2 3.97Å
267R84Confident78.9Confident35 Ų3564.8 Ų64.813%0.13229%0.29CS..EExtended strand (participates in β ladder)trans-66.8136.6176.6-167.4173.1-64.5-99-2112N185 F221 G259 R269 F326 E330N185-R267 PolarHBondContact ND2-NH2 3Å; F221-R267 HydrophobicContact CD1-CB 4.13Å; F221-R267 HydrophobicContact CD1-CG 4.41Å; F221-R267 HydrophobicContact CE1-CB 4.12Å; F221-R267 HydrophobicContact CE1-CG 4.22Å; G259-R267 PolarHBondContact O-NH2 3.02Å; R267-R269 PolarHBondContact O-N 2.69Å; R267-F326 VanDerWaalsContact CZ-CB 3.46Å; R267-F326 VanDerWaalsContact CZ-CG 3.48Å; R267-E330 IonicContact CZ-OE1 3.1Å; R267-E330 IonicContact NE-OE1 3.99Å; R267-E330 PolarHBondContact NE-OE1 3.4Å; R267-E330 IonicContact NH2-OE1 2.68Å; R267-E330 PolarHBondContact NH2-OE1 2.82Å
268N87.6Confident80.8Confident4 Ų465 Ų652%0.02129%0.294CS..  trans-75.6101.9174.5-172.62.9000110.7D217 R219 I220 L222 N270 Y271D217-N268 WeakPolarHBondContact CB-ND2 3.39Å; D217-N268 PolarHBondContact OD2-ND2 3.43Å; R219-N268 WeakPolarHBondContact O-CB 3.47Å; R219-N268 PolarHBondContact O-ND2 3.44Å; I220-N268 WeakPolarHBondContact O-CB 3.42Å; I220-N268 PolarHBondContact O-N 3.15Å; L222-N268 HydrophobicContact CD1-CB 4.12Å; L222-N268 HydrophobicContact CD2-CB 4.46Å; L222-N268 HydrophobicContact CG-CB 3.91Å; N268-N270 PolarHBondContact O-N 2.95Å; N268-N270 VanDerWaalsContact O-N 3.16Å; N268-N270 WeakPolarHBondContact OD1-CB 3.37Å; N268-N270 PolarHBondContact OD1-N 3.39Å; N268-Y271 VanDerWaalsContact O-CB 3.32Å; N268-Y271 WeakPolarHBondContact O-CB 3.39Å; N268-Y271 PolarHBondContact O-N 2.8Å; N268-Y271 VanDerWaalsContact O-N 3.1Å
269R88.4Confident82.6Confident205 Ų20563.6 Ų63.677%0.77429%0.285SS*.THydrogen-bonded Turntrans-62.9-20.1177.3-65.4-173.4179.9-170.8-0.1113.8R267 N323R267-R269 PolarHBondContact O-N 2.69Å; R269-N323 PolarHBondContact O-ND2 2.89Å
270N88.3Confident84.1Confident126 Ų12663.8 Ų63.867%0.67429%0.285SS*.THydrogen-bonded Turntrans-921.5179.6-61.2-35000113N268 R272N268-N270 PolarHBondContact O-N 2.95Å; N268-N270 VanDerWaalsContact O-N 3.16Å; N268-N270 WeakPolarHBondContact OD1-CB 3.37Å; N268-N270 PolarHBondContact OD1-N 3.39Å; N270-R272 PolarHBondContact O-N 2.91Å
271Y87Confident85Confident13 Ų1357.7 Ų57.75%0.05127%0.265CS..  trans-66.2116.1176.9179.2-100.6000110.2E180 I220 N268 G273 R274E180-Y271 WeakPolarHBondContact OE1-CE1 3.48Å; E180-Y271 PolarHBondContact OE1-OH 3.46Å; I220-Y271 HydrophobicContact CG1-CE2 4.2Å; N268-Y271 VanDerWaalsContact O-CB 3.32Å; N268-Y271 WeakPolarHBondContact O-CB 3.39Å; N268-Y271 PolarHBondContact O-N 2.8Å; N268-Y271 VanDerWaalsContact O-N 3.1Å; Y271-G273 VanDerWaalsContact CZ-CA 3.5Å; Y271-R274 PolarHBondContact OH-N 2.89Å
272R86.8Confident85.4Confident92 Ų9261.8 Ų61.835%0.34728%0.28SS..  trans-118.433.7-175.857.7-177.1-178.1-149-1.5112.1D215 W216 N270D215-R272 VanDerWaalsContact CG-NH2 3.33Å; D215-R272 IonicContact OD1-NH2 3.47Å; D215-R272 PolarHBondContact OD1-NH2 2.82Å; D215-R272 IonicContact OD2-CZ 3.53Å; D215-R272 IonicContact OD2-NH1 3.75Å; D215-R272 PolarHBondContact OD2-NH1 2.95Å; D215-R272 IonicContact OD2-NH2 2.93Å; D215-R272 PolarHBondContact OD2-NH2 2.67Å; W216-R272 HydrophobicContact CD2-CG 4.34Å; W216-R272 VanDerWaalsContact CE3-NH2 3.35Å; W216-R272 HydrophobicContact CH2-CG 3.88Å; W216-R272 HydrophobicContact CZ2-CG 3.69Å; W216-R272 HydrophobicContact CZ3-CG 4.31Å; N270-R272 PolarHBondContact O-N 2.91Å
273G86.6Confident85.5Confident0 Ų068.6 Ų68.60%030%0.3CS..SBendtrans84.7160.5-171.800000112.6H174 W216 Y271 W275H174-G273 VanDerWaalsContact CD2-CA 3.42Å; H174-G273 WeakPolarHBondContact CD2-CA 3.47Å; H174-G273 VanDerWaalsContact NE2-CA 3.33Å; H174-G273 WeakPolarHBondContact NE2-CA 2.95Å; W216-G273 VanDerWaalsContact CZ2-O 3.29Å; W216-G273 WeakPolarHBondContact CZ2-O 3.1Å; W216-G273 PolarHBondContact NE1-O 2.81Å; Y271-G273 VanDerWaalsContact CZ-CA 3.5Å; G273-W275 PolarHBondContact O-N 2.88Å
274R87.2Confident85.4Confident89 Ų8967.5 Ų67.534%0.33630%0.3SS..  trans-58.8135.7174.2-169.9176.8-179-142.5-0.6110.6N176 T178 E243 Y271 Q276N176-R274 PolarHBondContact ND2-O 2.06Å; T178-R274 WeakPolarHBondContact CG2-O 3.5Å; E243-R274 IonicContact OE1-CZ 3.66Å; E243-R274 IonicContact OE1-NE 3.95Å; E243-R274 PolarHBondContact OE1-NE 3.05Å; E243-R274 IonicContact OE1-NH2 3.57Å; E243-R274 PolarHBondContact OE1-NH2 2.96Å; Y271-R274 PolarHBondContact OH-N 2.89Å; R274-Q276 PolarHBondContact O-N 2.84Å
275W90.6Very high85Confident52 Ų5271 Ų7120%0.19734%0.336CS..  trans-65131.2173.3-17778.9000110.2R211 K212 W216 D218 G273 R277R211-W275 VanDerWaalsContact C-CZ2 3.48Å; K212-W275 HydrophobicContact CB-CD2 3.61Å; K212-W275 HydrophobicContact CB-CE3 3.89Å; K212-W275 HydrophobicContact CB-CG 4.02Å; K212-W275 HydrophobicContact CB-CH2 4.24Å; K212-W275 HydrophobicContact CB-CZ2 4.03Å; K212-W275 HydrophobicContact CB-CZ3 4.19Å; K212-W275 HydrophobicContact CD-CB 3.95Å; K212-W275 HydrophobicContact CD-CD2 4.22Å; K212-W275 HydrophobicContact CD-CE3 4.37Å; K212-W275 HydrophobicContact CD-CG 4.04Å; K212-W275 HydrophobicContact CG-CB 4.02Å; K212-W275 HydrophobicContact CG-CD2 3.76Å; K212-W275 HydrophobicContact CG-CE3 4.27Å; K212-W275 HydrophobicContact CG-CG 3.61Å; K212-W275 VanDerWaalsContact N-CZ2 3.26Å; W216-W275 HydrophobicContact CD2-CB 4.03Å; W216-W275 AromaticContact CD2-CD1 3.72Å; W216-W275 HydrophobicContact CD2-CG 4.28Å; W216-W275 AromaticContact CE3-CD1 3.85Å; W216-W275 HydrophobicContact CG-CB 3.92Å; W216-W275 HydrophobicContact CG-CG 4.33Å; D218-W275 PolarHBondContact OD1-N 2.82Å; G273-W275 PolarHBondContact O-N 2.88Å; W275-R277 HydrophobicContact CH2-CG 3.47Å; W275-R277 VanDerWaalsContact CH2-CG 3.47Å; W275-R277 HydrophobicContact CZ2-CG 4.06Å; W275-R277 HydrophobicContact CZ3-CG 4.08Å
276Q88.6Confident84.5Confident32 Ų3271.5 Ų71.515%0.1535%0.349CS..  trans-137.1152.4168.2-67.4-172-11.300109.6T178 N192 R274T178-Q276 HydrophobicContact CG2-CB 4.03Å; T178-Q276 HydrophobicContact CG2-CG 3.7Å; N192-Q276 VanDerWaalsContact CG-OE1 3.3Å; N192-Q276 PolarHBondContact ND2-OE1 2.73Å; R274-Q276 PolarHBondContact O-N 2.84Å
277R90Very high83.9Confident95 Ų9572.1 Ų72.136%0.35835%0.35SS..PPolyproline II helixtrans-60.2124.8177.1-70.2176.5177.5-89.97109.2R206 Y208 T210 W275R206-R277 PolarHBondContact NH1-O 2.89Å; Y208-R277 PolarHBondContact O-NH1 2.81Å; T210-R277 PolarHBondContact O-NH1 2.76Å; W275-R277 HydrophobicContact CH2-CG 3.47Å; W275-R277 VanDerWaalsContact CH2-CG 3.47Å; W275-R277 HydrophobicContact CZ2-CG 4.06Å; W275-R277 HydrophobicContact CZ3-CG 4.08Å
278P88.8Confident83.5Confident37 Ų3778.2 Ų78.224%0.2438%0.378CS..PPolyproline II helixtrans-65.4152.2-17726.5-33.2000111.1N207 T210N207-P278 HydrophobicContact CB-CG 4.28Å; N207-P278 WeakPolarHBondContact CB-O 3.39Å; N207-P278 PolarHBondContact N-O 3.42Å; T210-P278 HydrophobicContact CG2-CG 4.03Å
279Y89.2Confident82.8Confident15 Ų1584.3 Ų84.36%0.05941%0.41CS..EExtended strand (participates in β ladder)trans-82.6142.4162.4-83.1-78.4000109.9I194 D195 H200 M204 R206 L290I194-Y279 HydrophobicContact CB-CD2 4.18Å; I194-Y279 HydrophobicContact CB-CE2 3.95Å; I194-Y279 HydrophobicContact CD1-CD2 3.22Å; I194-Y279 HydrophobicContact CD1-CE2 3.88Å; I194-Y279 HydrophobicContact CD1-CG 3.58Å; I194-Y279 HydrophobicContact CG1-CD2 4.21Å; I194-Y279 HydrophobicContact CG1-CE2 4.49Å; I194-Y279 HydrophobicContact CG2-CE2 4.18Å; D195-Y279 PolarHBondContact OD1-OH 3.26Å; H200-Y279 AromaticContact NE2-CZ 3.89Å; H200-Y279 PolarHBondContact NE2-OH 3.4Å; M204-Y279 HydrophobicContact CE-CD1 3.5Å; M204-Y279 VanDerWaalsContact CE-CD1 3.5Å; M204-Y279 HydrophobicContact CE-CD2 4.41Å; M204-Y279 HydrophobicContact CE-CE1 3.47Å; M204-Y279 VanDerWaalsContact CE-CE1 3.47Å; M204-Y279 HydrophobicContact CE-CE2 4.35Å; M204-Y279 HydrophobicContact CE-CG 3.97Å; M204-Y279 HydrophobicContact CG-CD1 3.63Å; M204-Y279 HydrophobicContact CG-CE1 4.4Å; M204-Y279 HydrophobicContact CG-CG 4.07Å; M204-Y279 HydrophobicContact SD-CD1 3.98Å; M204-Y279 HydrophobicContact SD-CG 4.08Å; R206-Y279 HydrophobicContact CB-CE1 4.44Å; R206-Y279 VanDerWaalsContact CD-CZ 3.5Å; R206-Y279 HydrophobicContact CG-CD1 4.2Å; R206-Y279 HydrophobicContact CG-CE1 3.61Å; R206-Y279 HydrophobicContact CG-CE2 4.44Å; R206-Y279 VanDerWaalsContact NE-CE2 3.29Å; R206-Y279 VanDerWaalsContact NE-CZ 3.29Å; R206-Y279 PolarHBondContact NE-OH 3.06Å; Y279-L290 WeakPolarHBondContact O-CB 3.5Å; Y279-L290 PolarHBondContact O-N 2.86Å; Y279-L290 VanDerWaalsContact O-N 3.1Å
280I88.1Confident82.3Confident4 Ų475.6 Ų75.62%0.02138%0.378CS..EExtended strand (participates in β ladder)trans-122.1147.5172.155.7171.3000109.1M204 V205 N207 E287 K288M204-I280 WeakPolarHBondContact CA-O 3.21Å; V205-I280 HydrophobicContact CG2-CD1 4.09Å; V205-I280 HydrophobicContact CG2-CG1 3.72Å; V205-I280 PolarHBondContact N-O 2.92Å; V205-I280 WeakPolarHBondContact O-CG1 3.23Å; V205-I280 PolarHBondContact O-N 3.26Å; N207-I280 HydrophobicContact CB-CD1 4.04Å; N207-I280 HydrophobicContact CB-CG1 4.05Å; N207-I280 HydrophobicContact CB-CG2 3.85Å; I280-E287 HydrophobicContact CD1-CB 4.23Å; I280-E287 HydrophobicContact CD1-CG 3.98Å; I280-K288 WeakPolarHBondContact CA-O 3.31Å
281I85.7Confident82Confident44 Ų4472 Ų7223%0.22636%0.358CS..EExtended strand (participates in β ladder)trans-92.6130168-62.4164.8000108.3I201 R283 K288 L290I201-I281 HydrophobicContact CD1-CD1 3.7Å; I201-I281 HydrophobicContact CD1-CG1 3.89Å; I281-R283 HydrophobicContact CG2-CB 4.12Å; I281-K288 PolarHBondContact N-O 3.19Å; I281-K288 PolarHBondContact O-N 2.93Å; I281-K288 VanDerWaalsContact O-N 3.16Å; I281-L290 HydrophobicContact CD1-CD1 3.7Å; I281-L290 HydrophobicContact CG1-CB 4.41Å; I281-L290 HydrophobicContact CG1-CD1 4.17Å; I281-L290 HydrophobicContact CG1-CD2 4.43Å
282K82.5Confident81.8Confident105 Ų10572.1 Ų72.146%0.45736%0.359SS..EExtended strand (participates in β ladder)trans-97.7103167.9-73.2-176.6173-176.10109.8Y203 V205 E287Y203-K282 WeakPolarHBondContact CB-O 3.36Å; Y203-K282 PolarHBondContact O-N 2.74Å; V205-K282 HydrophobicContact CG2-CD 3.83Å; V205-K282 HydrophobicContact CG2-CG 4.06Å; K282-E287 WeakPolarHBondContact CE-OE1 3.44Å; K282-E287 HydrophobicContact CG-CG 4.19Å; K282-E287 IonicContact NZ-OE1 3.63Å
283R77.6Confident81.7Confident183 Ų18371.8 Ų71.869%0.69136%0.364SS*.EExtended strand (participates in β ladder)trans-132.8130.4176.9-168.1175.7-178.3-176.20.7110.3I281 G285 G286I281-R283 HydrophobicContact CG2-CB 4.12Å; R283-G285 VanDerWaalsContact C-N 3.27Å; R283-G285 PolarHBondContact O-N 2.84Å; R283-G286 PolarHBondContact N-O 2.9Å; R283-G286 VanDerWaalsContact N-O 3.14Å; R283-G286 PolarHBondContact O-N 2.89Å
284N71.3Confident81.7Confident161 Ų16172.6 Ų72.686%0.86137%0.368SS*.THydrogen-bonded Turntrans49.143.8176.4-60.6-4.9000113.9G286N284-G286 PolarHBondContact O-N 2.8Å
285G70Confident81.8Confident92 Ų9269.3 Ų69.395%0.94836%0.362SS*.THydrogen-bonded Turntrans77.5-3.2178.300000115.7R283R283-G285 VanDerWaalsContact C-N 3.27Å; R283-G285 PolarHBondContact O-N 2.84Å
286G71.8Confident82Confident35 Ų3569.7 Ų69.736%0.36137%0.372SS..EExtended strand (participates in β ladder)trans-100.3150.8173.600000113.1R283 N284R283-G286 PolarHBondContact N-O 2.9Å; R283-G286 VanDerWaalsContact N-O 3.14Å; R283-G286 PolarHBondContact O-N 2.89Å; N284-G286 PolarHBondContact O-N 2.8Å
287E72.6Confident82.5Confident96 Ų9668.1 Ų68.145%0.44937%0.365SS..EExtended strand (participates in β ladder)trans-107.6125.1168.1-65.3-175.9166.300108.5I280 K282I280-E287 HydrophobicContact CD1-CB 4.23Å; I280-E287 HydrophobicContact CD1-CG 3.98Å; K282-E287 WeakPolarHBondContact CE-OE1 3.44Å; K282-E287 HydrophobicContact CG-CG 4.19Å; K282-E287 IonicContact NZ-OE1 3.63Å
288K75.1Confident82.8Confident163 Ų16364 Ų6471%0.70935%0.352SS*.EExtended strand (participates in β ladder)trans-120.5139171.1-70.1-171.5178.8-174.70110I280 I281 L290I280-K288 WeakPolarHBondContact CA-O 3.31Å; I281-K288 PolarHBondContact N-O 3.19Å; I281-K288 PolarHBondContact O-N 2.93Å; I281-K288 VanDerWaalsContact O-N 3.16Å; K288-L290 PolarHBondContact O-N 2.7Å
289N72Confident83.3Confident131 Ų13162.4 Ų62.470%0.70134%0.342SS*.EExtended strand (participates in β ladder)trans-58.7130.5170.2-73.8-23.2000109.1
290L78.5Confident83.8Confident22 Ų2261.7 Ų61.712%0.11534%0.339CS..  trans-89.3126.3173.1-17857.9000108.7Q177 I194 I201 M204 Y279 I281 K288Q177-L290 PolarHBondContact NE2-O 3.41Å; I194-L290 HydrophobicContact CD1-CD2 3.88Å; I201-L290 HydrophobicContact CD1-CD1 4.49Å; I201-L290 HydrophobicContact CD1-CD2 4.45Å; M204-L290 HydrophobicContact CG-CD2 3.75Å; M204-L290 HydrophobicContact SD-CD2 3.33Å; M204-L290 WeakPolarHBondContact SD-CD2 3.31Å; Y279-L290 WeakPolarHBondContact O-CB 3.5Å; Y279-L290 PolarHBondContact O-N 2.86Å; Y279-L290 VanDerWaalsContact O-N 3.1Å; I281-L290 HydrophobicContact CD1-CD1 3.7Å; I281-L290 HydrophobicContact CG1-CB 4.41Å; I281-L290 HydrophobicContact CG1-CD1 4.17Å; I281-L290 HydrophobicContact CG1-CD2 4.43Å; K288-L290 PolarHBondContact O-N 2.7Å
291Q82.5Confident84.2Confident51 Ų5161.5 Ų61.524%0.23834%0.338CS..  trans-121.2129.9151.3-177.2179.43.700105.9T83 L84 D293T83-Q291 PolarHBondContact O-NE2 3.04Å; L84-Q291 HydrophobicContact CD2-CG 4.46Å; Q291-D293 PolarHBondContact O-N 2.88Å
292L82Confident84.8Confident16 Ų1659.5 Ų59.58%0.08433%0.328CS..  trans-66.7121.8173.3-76.3164.9000108.8I193 I194 L199I193-L292 HydrophobicContact CG2-CD1 3.73Å; I194-L292 HydrophobicContact CG1-CD1 3.81Å; L199-L292 HydrophobicContact CB-CD1 4.28Å; L199-L292 HydrophobicContact CD1-CD1 3.8Å
293D85.4Confident85.4Confident85 Ų8555 Ų5546%0.45531%0.308SS..  trans-82.5118.6168-171.3-0.2000108.1L84 Q291 G295L84-D293 HydrophobicContact CD2-CB 3.97Å; L84-D293 HydrophobicContact CG-CB 4.43Å; Q291-D293 PolarHBondContact O-N 2.88Å; D293-G295 PolarHBondContact O-N 3.38Å; D293-G295 WeakPolarHBondContact OD1-CA 3.43Å; D293-G295 PolarHBondContact OD1-N 3.46Å
294H85.6Confident86.2Confident17 Ų1746.3 Ų46.38%0.07928%0.276CS..  trans-83.45.4174.2-66.3-72000112.3T83 H126T83-H294 HydrophobicContact CG2-CB 4.01Å; T83-H294 PolarHBondContact OG1-CD2 3.07Å; T83-H294 VanDerWaalsContact OG1-CD2 3.31Å; T83-H294 PolarHBondContact OG1-N 3.25Å; H126-H294 PolarHBondContact CD2-O 2.86Å; H126-H294 VanDerWaalsContact CD2-O 3.32Å; H126-H294 PolarHBondContact CE1-O 2.62Å; H126-H294 VanDerWaalsContact CE1-O 3.24Å; H126-H294 PolarHBondContact ND1-O 2.95Å; H126-H294 PolarHBondContact NE2-O 3.31Å
295G90.1Very high87.1Confident20 Ų2043.5 Ų43.521%0.20625%0.253CS..  trans78.1178.4-176.600000112.6D293 I297D293-G295 PolarHBondContact O-N 3.38Å; D293-G295 WeakPolarHBondContact OD1-CA 3.43Å; D293-G295 PolarHBondContact OD1-N 3.46Å; G295-I297 PolarHBondContact O-N 2.9Å
296S95.3Very high88Confident59 Ų5939.1 Ų39.141%0.41321%0.208SC..  trans-76119.4174.9-175.10000109.9F81 P111 A112 H126F81-S296 CarbonylContact O-C 3.53Å; F81-S296 WeakPolarHBondContact O-CA 3.4Å; P111-S296 CarbonylContact C-O 3.46Å; P111-S296 VanDerWaalsContact CA-O 3.27Å; P111-S296 WeakPolarHBondContact CA-O 3.47Å; A112-S296 VanDerWaalsContact CB-OG 3.25Å; A112-S296 WeakPolarHBondContact CB-OG 3.3Å; A112-S296 PolarHBondContact N-O 3.41Å; H126-S296 PolarHBondContact NE2-O 2.74Å
297I97.6Very high88.9Confident0 Ų039.9 Ų39.90%020%0.203CC..EExtended strand (participates in β ladder)trans-95.4128.1175.2-55.3160.7000107.4L77 P80 F81 T83 L88 L109 G295L77-I297 HydrophobicContact CD1-CG2 3.77Å; P80-I297 CarbonylContact C-O 3.53Å; P80-I297 VanDerWaalsContact CA-O 3.25Å; P80-I297 WeakPolarHBondContact CA-O 3.38Å; F81-I297 HydrophobicContact CD1-CB 4.3Å; F81-I297 HydrophobicContact CE1-CB 4.01Å; F81-I297 HydrophobicContact CE1-CD1 4.19Å; F81-I297 HydrophobicContact CE1-CG2 4.14Å; F81-I297 HydrophobicContact CE2-CD1 4.18Å; F81-I297 HydrophobicContact CZ-CB 4.49Å; F81-I297 HydrophobicContact CZ-CD1 3.8Å; F81-I297 PolarHBondContact N-O 3.38Å; F81-I297 PolarHBondContact O-N 2.67Å; T83-I297 HydrophobicContact CG2-CD1 4.11Å; L88-I297 HydrophobicContact CD1-CD1 4.39Å; L88-I297 HydrophobicContact CD2-CD1 4.43Å; L109-I297 HydrophobicContact CB-CG2 4.06Å; L109-I297 HydrophobicContact CD1-CD1 4.23Å; L109-I297 HydrophobicContact CD2-CG2 4.36Å; G295-I297 PolarHBondContact O-N 2.9Å
298G98Very high89.7Confident8 Ų836.8 Ų36.88%0.08219%0.191CC..EExtended strand (participates in β ladder)trans-141-2.5-178.200000115.3K76 L77 L110K76-G298 WeakPolarHBondContact CA-O 3.22Å; L77-G298 PolarHBondContact N-O 2.92Å; L110-G298 PolarHBondContact O-N 2.84Å
299A98.6Very high90.4Very high3 Ų330.2 Ų30.23%0.02517%0.165CC..EExtended strand (participates in β ladder)trans-149.6165.3172.500000111.3R75 L110 L116R75-A299 CarbonylContact O-C 3.58Å; R75-A299 WeakPolarHBondContact O-CA 3.4Å; R75-A299 VanDerWaalsContact O-CB 3.22Å; R75-A299 WeakPolarHBondContact O-CB 3.35Å; L110-A299 HydrophobicContact CB-CB 3.95Å; L110-A299 HydrophobicContact CD1-CB 4.07Å; L110-A299 PolarHBondContact N-O 3.29Å; L110-A299 PolarHBondContact O-N 3.01Å; L116-A299 HydrophobicContact CD2-CB 3.82Å
300V98.6Very high91.4Very high0 Ų025.8 Ų25.80%014%0.14CC..EExtended strand (participates in β ladder)trans-126.8150.4172.868.30000108.8L19 W33 S74 R75 L77 I107 K108 L109 I318L19-V300 HydrophobicContact CD2-CB 4.48Å; L19-V300 HydrophobicContact CD2-CG1 3.63Å; W33-V300 HydrophobicContact CH2-CG1 4.28Å; S74-V300 CarbonylContact C-O 3.53Å; S74-V300 WeakPolarHBondContact CA-O 3.34Å; S74-V300 VanDerWaalsContact CB-O 3.28Å; S74-V300 WeakPolarHBondContact CB-O 3.41Å; R75-V300 HydrophobicContact CB-CG1 4.48Å; R75-V300 PolarHBondContact N-O 2.91Å; R75-V300 PolarHBondContact O-N 2.97Å; L77-V300 HydrophobicContact CD2-CB 4.24Å; L77-V300 HydrophobicContact CD2-CG1 4.36Å; I107-V300 HydrophobicContact CD1-CG2 3.23Å; I107-V300 HydrophobicContact CG1-CG2 3.38Å; K108-V300 CarbonylContact O-C 3.59Å; K108-V300 VanDerWaalsContact O-CA 3.29Å; K108-V300 WeakPolarHBondContact O-CA 3.26Å; K108-V300 WeakPolarHBondContact O-CG2 3.49Å; L109-V300 HydrophobicContact CD2-CG2 4.27Å; V300-I318 HydrophobicContact CB-CD1 4.28Å; V300-I318 HydrophobicContact CG2-CD1 4.36Å
301G98.2Very high92.1Very high0 Ų024.8 Ų24.80%014%0.135CC..EExtended strand (participates in β ladder)trans-159.9154.9176.100000115.5L73 K108L73-G301 CarbonylContact O-C 3.58Å; L73-G301 WeakPolarHBondContact O-CA 3.46Å; K108-G301 PolarHBondContact N-O 3.09Å; K108-G301 PolarHBondContact O-N 3.19Å
302F97.6Very high92.8Very high3 Ų322.6 Ų22.61%0.01313%0.125CC..EExtended strand (participates in β ladder)trans-103.3119.2169.6-62.3-71000108.1W33 L62 Y71 Q72 L73 Y92 I107 F119 L304 F313 I316W33-F302 AromaticContact CH2-CD2 3.88Å; W33-F302 HydrophobicContact CH2-CD2 3.88Å; W33-F302 AromaticContact CH2-CE2 3.5Å; W33-F302 HydrophobicContact CH2-CE2 3.5Å; W33-F302 VanDerWaalsContact CH2-CE2 3.5Å; W33-F302 HydrophobicContact CZ2-CE2 4.48Å; W33-F302 AromaticContact CZ3-CD2 3.68Å; W33-F302 HydrophobicContact CZ3-CD2 3.68Å; W33-F302 AromaticContact CZ3-CE2 3.82Å; W33-F302 HydrophobicContact CZ3-CE2 3.82Å; L62-F302 HydrophobicContact CD2-CD2 4.12Å; L62-F302 HydrophobicContact CD2-CE2 4.29Å; Y71-F302 CarbonylContact O-C 3.39Å; Q72-F302 CarbonylContact C-O 3.58Å; Q72-F302 VanDerWaalsContact CA-O 3.24Å; Q72-F302 WeakPolarHBondContact CA-O 3.35Å; L73-F302 PolarHBondContact N-O 3.48Å; L73-F302 PolarHBondContact O-N 3.01Å; Y92-F302 HydrophobicContact CD2-CE1 4.48Å; Y92-F302 HydrophobicContact CE2-CE1 4.31Å; I107-F302 HydrophobicContact CB-CD1 4.27Å; I107-F302 HydrophobicContact CB-CE1 3.82Å; I107-F302 HydrophobicContact CB-CZ 4.49Å; I107-F302 HydrophobicContact CD1-CE1 3.85Å; I107-F302 HydrophobicContact CD1-CE2 4.35Å; I107-F302 HydrophobicContact CD1-CZ 3.65Å; I107-F302 HydrophobicContact CG1-CD1 4.09Å; I107-F302 HydrophobicContact CG1-CE1 3.66Å; I107-F302 HydrophobicContact CG1-CZ 3.94Å; F119-F302 WeakPolarHBondContact CE1-O 3.39Å; F302-L304 HydrophobicContact CB-CD1 4.02Å; F302-L304 HydrophobicContact CB-CG 4.12Å; F302-L304 HydrophobicContact CD1-CD1 4.22Å; F302-L304 HydrophobicContact CG-CD1 4.46Å; F302-F313 HydrophobicContact CD1-CD1 4.19Å; F302-F313 HydrophobicContact CD1-CE1 4.18Å; F302-F313 HydrophobicContact CE1-CB 4.48Å; F302-F313 AromaticContact CE1-CD1 3.55Å; F302-F313 HydrophobicContact CE1-CD1 3.55Å; F302-F313 AromaticContact CE1-CE1 3.91Å; F302-F313 HydrophobicContact CE1-CE1 3.91Å; F302-F313 HydrophobicContact CE1-CG 4.08Å; F302-F313 HydrophobicContact CE2-CB 4.37Å; F302-F313 HydrophobicContact CZ-CB 3.96Å; F302-F313 AromaticContact CZ-CD1 3.89Å; F302-F313 HydrophobicContact CZ-CD1 3.89Å; F302-F313 HydrophobicContact CZ-CG 4.03Å; F302-I316 HydrophobicContact CE2-CD1 3.8Å; F302-I316 HydrophobicContact CZ-CD1 3.81Å; F302-I316 HydrophobicContact CZ-CG1 4.5Å
303D95.3Very high93.5Very high9 Ų922 Ų225%0.04812%0.122CC..EExtended strand (participates in β ladder)trans-123.793.6171.7161.155.3000106.9Y71 Q72 Y106 K108 F119 S121Y71-D303 WeakPolarHBondContact O-CA 3.05Å; Q72-D303 HydrophobicContact CG-CB 4.22Å; Q72-D303 VanDerWaalsContact CG-OD1 3.25Å; Q72-D303 WeakPolarHBondContact CG-OD1 3.5Å; Q72-D303 PolarHBondContact NE2-OD1 3.29Å; Q72-D303 VanDerWaalsContact NE2-OD1 3.1Å; Y106-D303 WeakPolarHBondContact CE2-O 3.46Å; K108-D303 HydrophobicContact CD-CB 4.37Å; K108-D303 IonicContact NZ-OD2 2.64Å; K108-D303 PolarHBondContact NZ-OD2 3.07Å; F119-D303 HydrophobicContact CE1-CB 3.85Å; F119-D303 HydrophobicContact CE2-CB 4.3Å; F119-D303 HydrophobicContact CZ-CB 3.57Å; S121-D303 WeakPolarHBondContact CA-OD2 3.32Å; S121-D303 PolarHBondContact N-OD1 2.92Å; S121-D303 PolarHBondContact N-OD2 2.67Å
304L93.9Very high94Very high2 Ų218.2 Ų18.21%0.0110%0.102CC..EExtended strand (participates in β ladder)trans-127.8139.2-164.8-53.9176.7000110.8Y70 Y71 G104 Y106 F302 I306 F313Y70-L304 CarbonylContact C-O 3.54Å; Y70-L304 WeakPolarHBondContact CA-O 3.28Å; Y71-L304 PolarHBondContact N-O 3Å; Y71-L304 PolarHBondContact O-N 3.07Å; G104-L304 WeakPolarHBondContact O-CD2 3.47Å; Y106-L304 HydrophobicContact CD2-CD2 3.96Å; Y106-L304 HydrophobicContact CE1-CD2 4.43Å; Y106-L304 HydrophobicContact CE2-CD2 3.82Å; Y106-L304 HydrophobicContact CG-CD2 4.33Å; Y106-L304 WeakPolarHBondContact O-CD2 3.36Å; F302-L304 HydrophobicContact CB-CD1 4.02Å; F302-L304 HydrophobicContact CB-CG 4.12Å; F302-L304 HydrophobicContact CD1-CD1 4.22Å; F302-L304 HydrophobicContact CG-CD1 4.46Å; L304-I306 HydrophobicContact CB-CD1 4.06Å; L304-I306 HydrophobicContact CB-CG1 3.92Å; L304-I306 HydrophobicContact CD1-CD1 4.11Å; L304-F313 HydrophobicContact CD1-CE1 4.2Å; L304-F313 HydrophobicContact CD1-CE2 3.95Å; L304-F313 HydrophobicContact CD1-CZ 3.44Å; L304-F313 VanDerWaalsContact CD1-CZ 3.44Å
305W90.6Very high94.4Very high101 Ų10118.3 Ų18.338%0.38310%0.103SC..EExtended strand (participates in β ladder)trans-99120.2161.6173.9-104.4000108.9F68 Y70F68-W305 HydrophobicContact CB-CH2 3.94Å; F68-W305 HydrophobicContact CB-CZ2 3.98Å; F68-W305 HydrophobicContact CD1-CZ2 4.16Å; F68-W305 WeakPolarHBondContact O-CH2 3.19Å; Y70-W305 HydrophobicContact CD1-CB 4.29Å; Y70-W305 AromaticContact CD1-CE3 3.9Å; Y70-W305 HydrophobicContact CD1-CE3 3.9Å; Y70-W305 AromaticContact CD2-CE3 3.73Å; Y70-W305 HydrophobicContact CD2-CE3 3.73Å; Y70-W305 AromaticContact CD2-CZ3 3.77Å; Y70-W305 HydrophobicContact CD2-CZ3 3.77Å; Y70-W305 HydrophobicContact CE1-CB 4.08Å; Y70-W305 HydrophobicContact CE1-CD2 4.44Å; Y70-W305 AromaticContact CE1-CE3 3.81Å; Y70-W305 HydrophobicContact CE1-CE3 3.81Å; Y70-W305 AromaticContact CE2-CE3 3.63Å; Y70-W305 HydrophobicContact CE2-CE3 3.63Å; Y70-W305 AromaticContact CE2-CZ3 3.67Å; Y70-W305 HydrophobicContact CE2-CZ3 3.67Å; Y70-W305 AromaticContact CG-CE3 3.86Å; Y70-W305 HydrophobicContact CG-CE3 3.86Å; Y70-W305 HydrophobicContact CG-CZ3 4.31Å; Y70-W305 AromaticContact CZ-CE3 3.69Å
306I89.2Confident94.8Very high0 Ų017.3 Ų17.30%09%0.093CC..EExtended strand (participates in β ladder)trans-120.7121.9-172.1-60.9-175.1000110.4P64 F68 R69 Y71 L304 T308 P309 I311P64-I306 HydrophobicContact CB-CD1 3.69Å; P64-I306 HydrophobicContact CB-CG2 4.49Å; P64-I306 HydrophobicContact CG-CD1 3.3Å; F68-I306 WeakPolarHBondContact CA-O 3.23Å; F68-I306 PolarHBondContact N-O 3.42Å; R69-I306 PolarHBondContact N-O 3.44Å; R69-I306 PolarHBondContact O-N 2.95Å; R69-I306 VanDerWaalsContact O-N 3.09Å; Y71-I306 HydrophobicContact CD2-CB 3.92Å; Y71-I306 HydrophobicContact CD2-CD1 3.66Å; Y71-I306 HydrophobicContact CD2-CG1 3.85Å; Y71-I306 HydrophobicContact CE2-CB 3.86Å; Y71-I306 HydrophobicContact CE2-CD1 4.12Å; Y71-I306 HydrophobicContact CE2-CG1 4.27Å; Y71-I306 HydrophobicContact CE2-CG2 4.5Å; Y71-I306 HydrophobicContact CG-CD1 4.17Å; L304-I306 HydrophobicContact CB-CD1 4.06Å; L304-I306 HydrophobicContact CB-CG1 3.92Å; L304-I306 HydrophobicContact CD1-CD1 4.11Å; I306-T308 VanDerWaalsContact CG2-C 3.49Å; I306-T308 VanDerWaalsContact CG2-O 3.32Å; I306-T308 WeakPolarHBondContact CG2-O 3.24Å; I306-P309 HydrophobicContact CG2-CB 4.29Å; I306-I311 HydrophobicContact CD1-CD1 4.5Å
307I90.3Very high94.8Very high51 Ų5114.6 Ų14.626%0.2627%0.074SC..SBendtrans-89.8-43.6172.2-60.8-175.5000110.1S67 F68 C102 P309S67-I307 WeakPolarHBondContact CA-O 3.43Å; S67-I307 WeakPolarHBondContact CB-O 3.49Å; S67-I307 PolarHBondContact OG-O 3.24Å; F68-I307 HydrophobicContact CD1-CG1 4.16Å; F68-I307 HydrophobicContact CD1-CG2 4.27Å; F68-I307 HydrophobicContact CE1-CB 4.36Å; F68-I307 HydrophobicContact CE1-CD1 4.32Å; F68-I307 HydrophobicContact CE1-CG1 4.13Å; F68-I307 HydrophobicContact CE1-CG2 3.63Å; F68-I307 HydrophobicContact CZ-CG2 3.78Å; C102-I307 HydrophobicContact CB-CD1 4.08Å; I307-P309 WeakPolarHBondContact O-CD 3.45Å
308T89.7Confident94.8Very high32 Ų3214.6 Ų14.620%0.1967%0.074CC..SBendtrans-111.1102.2179.5-53.50000109.8I306 E310I306-T308 VanDerWaalsContact CG2-C 3.49Å; I306-T308 VanDerWaalsContact CG2-O 3.32Å; I306-T308 WeakPolarHBondContact CG2-O 3.24Å; T308-E310 HydrophobicContact CG2-CB 3.95Å; T308-E310 HydrophobicContact CG2-CG 3.79Å; T308-E310 PolarHBondContact O-N 2.87Å
309P90.2Very high94.8Very high24 Ų2414.2 Ų14.216%0.1567%0.07CC..  trans-79.448.2-176.936.5-39.4000111.9P64 S67 I306 I307P64-P309 HydrophobicContact CB-CB 4.08Å; P64-P309 WeakPolarHBondContact O-CB 3.46Å; P64-P309 VanDerWaalsContact O-O 3.06Å; S67-P309 WeakPolarHBondContact OG-CD 3.46Å; I306-P309 HydrophobicContact CG2-CB 4.29Å; I307-P309 WeakPolarHBondContact O-CD 3.45Å
310E91.3Very high94.6Very high39 Ų3915.4 Ų15.418%0.1828%0.076CC..  trans-115.448.3-177.8-64.6-102.9-177.400108.3N96 Q97 R98 T308N96-E310 CarbonylContact C-O 3.5Å; Q97-E310 HydrophobicContact CB-CB 4.17Å; Q97-E310 PolarHBondContact N-O 2.81Å; R98-E310 WeakPolarHBondContact CD-OE2 3.46Å; R98-E310 WeakPolarHBondContact CG-OE2 3.3Å; R98-E310 IonicContact CZ-OE1 2.74Å; R98-E310 IonicContact CZ-OE2 2.93Å; R98-E310 IonicContact NE-OE1 3.33Å; R98-E310 PolarHBondContact NE-OE1 3.18Å; R98-E310 IonicContact NE-OE2 2.9Å; R98-E310 PolarHBondContact NE-OE2 2.85Å; R98-E310 VanDerWaalsContact NE-OE2 3.1Å; R98-E310 IonicContact NH1-OE1 2.75Å; R98-E310 PolarHBondContact NH1-OE1 2.88Å; R98-E310 IonicContact NH2-OE1 3.88Å; R98-E310 IonicContact NH2-OE2 2.82Å; T308-E310 HydrophobicContact CG2-CB 3.95Å; T308-E310 HydrophobicContact CG2-CG 3.79Å; T308-E310 PolarHBondContact O-N 2.87Å
311I94.9Very high94.2Very high0 Ų017 Ų170%08%0.084CC..EExtended strand (participates in β ladder)trans-124140.2-178.3-58165.6000109P64 V94 K95 I100 A103 I306 F313P64-I311 WeakPolarHBondContact CD-O 3.44Å; V94-I311 HydrophobicContact CG1-CG2 3.86Å; K95-I311 CarbonylContact O-C 3.57Å; K95-I311 VanDerWaalsContact O-CA 3.25Å; K95-I311 WeakPolarHBondContact O-CA 3.31Å; I100-I311 HydrophobicContact CD1-CD1 3.7Å; I100-I311 HydrophobicContact CD1-CG1 3.24Å; A103-I311 HydrophobicContact CB-CD1 3.45Å; A103-I311 VanDerWaalsContact CB-CD1 3.45Å; I306-I311 HydrophobicContact CD1-CD1 4.5Å; I311-F313 HydrophobicContact CB-CE2 4.12Å; I311-F313 HydrophobicContact CB-CZ 4.4Å; I311-F313 HydrophobicContact CG2-CD1 4.49Å; I311-F313 HydrophobicContact CG2-CD2 4Å; I311-F313 HydrophobicContact CG2-CE1 4.04Å; I311-F313 HydrophobicContact CG2-CE2 3.49Å; I311-F313 VanDerWaalsContact CG2-CE2 3.49Å; I311-F313 HydrophobicContact CG2-CG 4.47Å; I311-F313 HydrophobicContact CG2-CZ 3.51Å
312V95.9Very high93.8Very high6 Ų617.5 Ų17.54%0.0369%0.087CC..EExtended strand (participates in β ladder)trans-118.3127.3169.3-165.80000108.6Q63 V94 K95 Q97Q63-V312 HydrophobicContact CG-CB 4.25Å; Q63-V312 HydrophobicContact CG-CG1 4.06Å; Q63-V312 HydrophobicContact CG-CG2 3.89Å; V94-V312 WeakPolarHBondContact CA-O 3.39Å; K95-V312 HydrophobicContact CB-CB 4.11Å; K95-V312 HydrophobicContact CB-CG2 4.41Å; K95-V312 HydrophobicContact CD-CG2 4.3Å; K95-V312 PolarHBondContact N-O 2.79Å; K95-V312 PolarHBondContact O-N 3.07Å; Q97-V312 HydrophobicContact CG-CG2 3.93Å
313F97.1Very high93.3Very high2 Ų219.3 Ų19.31%0.00910%0.097CC..EExtended strand (participates in β ladder)trans-107.9130.6173-59.2-87.8000109.7G61 L62 P64 Y92 S93 V94 A105 F302 L304 I311G61-F313 CarbonylContact C-O 3.59Å; G61-F313 WeakPolarHBondContact CA-O 3.23Å; L62-F313 HydrophobicContact CB-CB 4.39Å; L62-F313 PolarHBondContact N-O 3.47Å; L62-F313 PolarHBondContact O-N 3.47Å; P64-F313 HydrophobicContact CG-CE2 4.09Å; Y92-F313 HydrophobicContact CD2-CD1 4.35Å; Y92-F313 HydrophobicContact CE2-CD1 4.16Å; S93-F313 WeakPolarHBondContact O-CA 3.43Å; V94-F313 HydrophobicContact CG2-CD1 4.09Å; V94-F313 HydrophobicContact CG2-CE1 4.22Å; A105-F313 HydrophobicContact CB-CE1 3.62Å; A105-F313 HydrophobicContact CB-CZ 3.81Å; F302-F313 HydrophobicContact CD1-CD1 4.19Å; F302-F313 HydrophobicContact CD1-CE1 4.18Å; F302-F313 HydrophobicContact CE1-CB 4.48Å; F302-F313 AromaticContact CE1-CD1 3.55Å; F302-F313 HydrophobicContact CE1-CD1 3.55Å; F302-F313 AromaticContact CE1-CE1 3.91Å; F302-F313 HydrophobicContact CE1-CE1 3.91Å; F302-F313 HydrophobicContact CE1-CG 4.08Å; F302-F313 HydrophobicContact CE2-CB 4.37Å; F302-F313 HydrophobicContact CZ-CB 3.96Å; F302-F313 AromaticContact CZ-CD1 3.89Å; F302-F313 HydrophobicContact CZ-CD1 3.89Å; F302-F313 HydrophobicContact CZ-CG 4.03Å; L304-F313 HydrophobicContact CD1-CE1 4.2Å; L304-F313 HydrophobicContact CD1-CE2 3.95Å; L304-F313 HydrophobicContact CD1-CZ 3.44Å; L304-F313 VanDerWaalsContact CD1-CZ 3.44Å; I311-F313 HydrophobicContact CB-CE2 4.12Å; I311-F313 HydrophobicContact CB-CZ 4.4Å; I311-F313 HydrophobicContact CG2-CD1 4.49Å; I311-F313 HydrophobicContact CG2-CD2 4Å; I311-F313 HydrophobicContact CG2-CE1 4.04Å; I311-F313 HydrophobicContact CG2-CE2 3.49Å; I311-F313 VanDerWaalsContact CG2-CE2 3.49Å; I311-F313 HydrophobicContact CG2-CG 4.47Å; I311-F313 HydrophobicContact CG2-CZ 3.51Å
314D95.8Very high93Very high7 Ų721.9 Ų21.94%0.03711%0.108CC..EExtended strand (participates in β ladder)trans-154.5178.3-178-169.922000111.7R22 F23 K60 S93 I316R22-D314 WeakPolarHBondContact CA-OD1 3.39Å; F23-D314 WeakPolarHBondContact CD2-OD1 3.39Å; K60-D314 VanDerWaalsContact O-CG 3.24Å; S93-D314 PolarHBondContact N-O 3.12Å; S93-D314 PolarHBondContact O-N 3.02Å; S93-D314 VanDerWaalsContact OG-C 3.25Å; S93-D314 WeakPolarHBondContact OG-CB 3.26Å; S93-D314 PolarHBondContact OG-O 3.05Å; S93-D314 VanDerWaalsContact OG-O 3.06Å; D314-I316 VanDerWaalsContact C-N 3.31Å; D314-I316 PolarHBondContact O-N 3.39Å
315N95Very high92.8Very high18 Ų1821.8 Ų21.810%0.09611%0.108CC..EExtended strand (participates in β ladder)trans5541.4171-57.7-72.9000113.5E21 Y92 S93 F168 L317 F328E21-N315 CarbonylContact O-C 3.52Å; E21-N315 WeakPolarHBondContact O-CA 3.4Å; E21-N315 PolarHBondContact O-N 3.44Å; Y92-N315 WeakPolarHBondContact CA-O 3.43Å; S93-N315 PolarHBondContact OG-ND2 2.76Å; F168-N315 HydrophobicContact CE1-CB 3.54Å; F168-N315 HydrophobicContact CZ-CB 3.73Å; N315-L317 PolarHBondContact O-N 3.15Å; N315-F328 HydrophobicContact CB-CE1 4.25Å; N315-F328 HydrophobicContact CB-CZ 4.17Å; N315-F328 WeakPolarHBondContact OD1-CZ 3.35Å
316I97.4Very high92.5Very high0 Ų017.2 Ų17.20%09%0.091CC..EExtended strand (participates in β ladder)trans-76.2109.8-176.9-53.2163.3000108.4L19 D20 E21 F23 W33 Q91 I107 F302 D314L19-I316 HydrophobicContact CD2-CG2 3.86Å; D20-I316 WeakPolarHBondContact CA-O 3.41Å; E21-I316 HydrophobicContact CB-CB 4.23Å; E21-I316 PolarHBondContact N-O 2.75Å; E21-I316 PolarHBondContact O-N 3.14Å; F23-I316 HydrophobicContact CE2-CD1 4.18Å; F23-I316 HydrophobicContact CZ-CD1 4.24Å; W33-I316 HydrophobicContact CH2-CD1 3.69Å; W33-I316 HydrophobicContact CZ2-CD1 3.58Å; Q91-I316 CarbonylContact O-C 3.53Å; Q91-I316 WeakPolarHBondContact O-CA 3.41Å; I107-I316 HydrophobicContact CD1-CD1 4.34Å; I107-I316 HydrophobicContact CD1-CG1 4.4Å; I107-I316 HydrophobicContact CD1-CG2 3.83Å; F302-I316 HydrophobicContact CE2-CD1 3.8Å; F302-I316 HydrophobicContact CZ-CD1 3.81Å; F302-I316 HydrophobicContact CZ-CG1 4.5Å; D314-I316 VanDerWaalsContact C-N 3.31Å; D314-I316 PolarHBondContact O-N 3.39Å
317L96.6Very high92.2Very high2 Ų223.4 Ų23.41%0.0112%0.118CC..EExtended strand (participates in β ladder)trans-124.3125-175.6177.562.1000110.2V17 L19 D20 Q91 N315 T319 V325V17-L317 HydrophobicContact CG1-CD1 4.04Å; L19-L317 WeakPolarHBondContact O-CA 3.5Å; D20-L317 HydrophobicContact CB-CD1 4.15Å; Q91-L317 HydrophobicContact CB-CB 4.33Å; Q91-L317 PolarHBondContact N-O 3.46Å; Q91-L317 PolarHBondContact O-N 2.84Å; N315-L317 PolarHBondContact O-N 3.15Å; L317-T319 HydrophobicContact CG-CG2 4.47Å; L317-V325 HydrophobicContact CD2-CB 4.39Å; L317-V325 HydrophobicContact CD2-CG2 3.67Å; L317-V325 HydrophobicContact CG-CG2 4.29Å
318I97.7Very high92Very high0 Ų021.6 Ų21.60%011%0.108CC..EExtended strand (participates in β ladder)trans-124.8119.1174.8-56.3171.2000108.3Y18 L19 L77 F81 L88 V89 L90 L109 V300Y18-I318 HydrophobicContact CD2-CG2 4.14Å; Y18-I318 PolarHBondContact N-O 3.2Å; L19-I318 HydrophobicContact CB-CB 4.18Å; L19-I318 HydrophobicContact CB-CD1 4.28Å; L19-I318 HydrophobicContact CB-CG1 4.36Å; L19-I318 HydrophobicContact CD2-CD1 4Å; L19-I318 PolarHBondContact N-O 3.26Å; L19-I318 PolarHBondContact O-N 3.34Å; L77-I318 HydrophobicContact CD2-CD1 3.56Å; F81-I318 HydrophobicContact CE1-CG2 3.77Å; F81-I318 HydrophobicContact CZ-CG2 3.69Å; L88-I318 HydrophobicContact CD1-CG2 4.27Å; V89-I318 VanDerWaalsContact O-CA 3.3Å; V89-I318 WeakPolarHBondContact O-CA 3.35Å; L90-I318 HydrophobicContact CD1-CD1 4.19Å; L90-I318 HydrophobicContact CD1-CG1 3.82Å; L109-I318 HydrophobicContact CD2-CD1 3.61Å; V300-I318 HydrophobicContact CB-CD1 4.28Å; V300-I318 HydrophobicContact CG2-CD1 4.36Å
319T96.2Very high91.8Very high0 Ų020 Ų200%010%0.099CC..EExtended strand (participates in β ladder)trans-149.6168.9-175.7-175.90000111.7T16 V89 L317 D321 V325T16-T319 VanDerWaalsContact O-CA 3.28Å; T16-T319 WeakPolarHBondContact O-CA 3.31Å; T16-T319 WeakPolarHBondContact O-CB 3.49Å; T16-T319 PolarHBondContact O-OG1 3.03Å; V89-T319 HydrophobicContact CB-CG2 3.89Å; V89-T319 WeakPolarHBondContact CB-O 3.22Å; V89-T319 HydrophobicContact CG1-CG2 4.44Å; V89-T319 HydrophobicContact CG2-CG2 4.35Å; V89-T319 PolarHBondContact N-O 3.24Å; V89-T319 PolarHBondContact O-N 3.42Å; L317-T319 HydrophobicContact CG-CG2 4.47Å; T319-D321 WeakPolarHBondContact CG2-O 3.49Å; T319-D321 PolarHBondContact OG1-N 3.32Å; T319-V325 HydrophobicContact CG2-CG2 3.47Å; T319-V325 VanDerWaalsContact CG2-CG2 3.47Å
320D94.6Very high91.2Very high28 Ų2822.1 Ų22.115%0.1511%0.106CC..SBendtrans-100.13.9168.259.79.1000114.3T16 Y18 K86 S87T16-D320 PolarHBondContact N-OD1 3.48Å; T16-D320 PolarHBondContact O-N 3.36Å; Y18-D320 HydrophobicContact CE2-CB 3.95Å; Y18-D320 PolarHBondContact OH-OD2 2.95Å; K86-D320 HydrophobicContact CB-CB 4.19Å; K86-D320 WeakPolarHBondContact CD-OD2 3.31Å; K86-D320 IonicContact NZ-OD2 3.29Å; K86-D320 PolarHBondContact NZ-OD2 3.08Å; S87-D320 VanDerWaalsContact O-CA 3.26Å; S87-D320 WeakPolarHBondContact O-CA 3.4Å; S87-D320 VanDerWaalsContact O-CB 3.23Å; S87-D320 WeakPolarHBondContact O-CB 3.47Å
321D91.8Very high90.7Very high34 Ų3424.8 Ų24.818%0.18212%0.122CC..  trans-114.8113.7179.9-178.620.3000113.4P15 T319 N323 H324P15-D321 HydrophobicContact CB-CB 3.26Å; P15-D321 VanDerWaalsContact CB-OD2 3.3Å; P15-D321 WeakPolarHBondContact CB-OD2 3.32Å; P15-D321 HydrophobicContact CG-CB 4.48Å; T319-D321 WeakPolarHBondContact CG2-O 3.49Å; T319-D321 PolarHBondContact OG1-N 3.32Å; D321-N323 VanDerWaalsContact C-N 3.32Å; D321-N323 PolarHBondContact O-N 3.41Å; D321-N323 WeakPolarHBondContact OD1-CB 3.45Å; D321-N323 PolarHBondContact OD1-N 3.43Å; D321-N323 PolarHBondContact OD1-ND2 3.09Å; D321-H324 HydrophobicContact CB-CB 4.08Å; D321-H324 PolarHBondContact O-N 2.84Å; D321-H324 PolarHBondContact OD2-N 3.31Å
322T89.6Confident89.8Confident10 Ų1027.3 Ų27.36%0.06114%0.135CC..Hα-helixtrans-66.2-34.2175.954.10000112.2V89 I172 H324 V325 F326V89-T322 HydrophobicContact CG2-CG2 3.81Å; I172-T322 HydrophobicContact CD1-CG2 3.99Å; I172-T322 HydrophobicContact CG1-CG2 4.36Å; I172-T322 HydrophobicContact CG2-CG2 3.65Å; T322-H324 VanDerWaalsContact C-N 3.32Å; T322-H324 PolarHBondContact O-N 2.93Å; T322-V325 PolarHBondContact O-N 3.16Å; T322-F326 WeakPolarHBondContact O-CD2 3.06Å; T322-F326 WeakPolarHBondContact O-CE2 3.39Å; T322-F326 WeakPolarHBondContact O-CG 3.26Å; T322-F326 PolarHBondContact O-N 3.3Å
323N86.8Confident88.7Confident40 Ų4027.3 Ų27.321%0.21414%0.135CC..Hα-helixtrans-67.2-35.7-179.2-64.4-64.7000111.9R269 D321 F326 K327R269-N323 PolarHBondContact O-ND2 2.89Å; D321-N323 VanDerWaalsContact C-N 3.32Å; D321-N323 PolarHBondContact O-N 3.41Å; D321-N323 WeakPolarHBondContact OD1-CB 3.45Å; D321-N323 PolarHBondContact OD1-N 3.43Å; D321-N323 PolarHBondContact OD1-ND2 3.09Å; N323-F326 PolarHBondContact O-N 2.82Å; N323-K327 WeakPolarHBondContact O-CB 3.49Å; N323-K327 PolarHBondContact O-N 2.84Å
324H88Confident87.2Confident63 Ų6329.8 Ų29.829%0.29215%0.147SC..Hα-helixtrans-58.5-49.2175.6-172.180000111.1D321 T322 K327 F328D321-H324 HydrophobicContact CB-CB 4.08Å; D321-H324 PolarHBondContact O-N 2.84Å; D321-H324 PolarHBondContact OD2-N 3.31Å; T322-H324 VanDerWaalsContact C-N 3.32Å; T322-H324 PolarHBondContact O-N 2.93Å; H324-K327 PolarHBondContact O-N 2.82Å; H324-F328 WeakPolarHBondContact O-CB 3.32Å; H324-F328 PolarHBondContact O-N 3.15Å
325V89.6Confident85.9Confident0 Ų038.6 Ų38.60%018%0.18CC..Hα-helixtrans-63.6-45.2178.6178.80000112V89 Q91 T170 L317 T319 T322 K327 F328 D329V89-V325 HydrophobicContact CB-CG2 4.14Å; V89-V325 HydrophobicContact CG1-CB 4.11Å; V89-V325 HydrophobicContact CG1-CG1 4.2Å; V89-V325 HydrophobicContact CG1-CG2 3.4Å; Q91-V325 HydrophobicContact CB-CG1 4.2Å; Q91-V325 HydrophobicContact CG-CG1 4.42Å; T170-V325 HydrophobicContact CG2-CG1 3.94Å; L317-V325 HydrophobicContact CD2-CB 4.39Å; L317-V325 HydrophobicContact CD2-CG2 3.67Å; L317-V325 HydrophobicContact CG-CG2 4.29Å; T319-V325 HydrophobicContact CG2-CG2 3.47Å; T319-V325 VanDerWaalsContact CG2-CG2 3.47Å; T322-V325 PolarHBondContact O-N 3.16Å; V325-K327 VanDerWaalsContact C-N 3.31Å; V325-K327 PolarHBondContact O-N 2.8Å; V325-F328 WeakPolarHBondContact O-CB 3.16Å; V325-F328 PolarHBondContact O-N 3.31Å; V325-F328 VanDerWaalsContact O-N 3.16Å; V325-D329 PolarHBondContact O-N 2.82Å
326F85.6Confident85.1Confident5 Ų539.3 Ų39.32%0.02218%0.183CC..Hα-helixtrans-63.8-38.7179.6-60.3-34000113.2I172 N185 R267 T322 N323 D329 E330I172-F326 HydrophobicContact CD1-CE1 3.83Å; I172-F326 HydrophobicContact CD1-CZ 3.7Å; N185-F326 VanDerWaalsContact OD1-CD1 3.23Å; N185-F326 WeakPolarHBondContact OD1-CD1 3.14Å; R267-F326 VanDerWaalsContact CZ-CB 3.46Å; R267-F326 VanDerWaalsContact CZ-CG 3.48Å; T322-F326 WeakPolarHBondContact O-CD2 3.06Å; T322-F326 WeakPolarHBondContact O-CE2 3.39Å; T322-F326 WeakPolarHBondContact O-CG 3.26Å; T322-F326 PolarHBondContact O-N 3.3Å; N323-F326 PolarHBondContact O-N 2.82Å; F326-D329 PolarHBondContact O-N 2.82Å; F326-E330 WeakPolarHBondContact O-CB 3.36Å; F326-E330 VanDerWaalsContact O-CG 3.31Å; F326-E330 WeakPolarHBondContact O-CG 3.13Å; F326-E330 PolarHBondContact O-N 2.91Å
327K82.6Confident84.4Confident130 Ų13042.6 Ų42.657%0.56520%0.196SC*.Hα-helixtrans-66.4-41.7175.1-176.4178.1176.9-170.80110.6N323 H324 V325 D329 E330 D331N323-K327 WeakPolarHBondContact O-CB 3.49Å; N323-K327 PolarHBondContact O-N 2.84Å; H324-K327 PolarHBondContact O-N 2.82Å; V325-K327 VanDerWaalsContact C-N 3.31Å; V325-K327 PolarHBondContact O-N 2.8Å; K327-D329 VanDerWaalsContact C-N 3.32Å; K327-D329 PolarHBondContact O-N 2.84Å; K327-E330 PolarHBondContact O-N 2.8Å; K327-D331 WeakPolarHBondContact CE-OD2 3.31Å; K327-D331 WeakPolarHBondContact CG-OD2 3.44Å; K327-D331 WeakPolarHBondContact O-CB 3.48Å; K327-D331 PolarHBondContact O-N 3.05Å
328F85.4Confident83.8Confident13 Ų1349.1 Ų49.16%0.05723%0.226CC..Hα-helixtrans-55.9-46.7175.2177.9-84.2000111.8F168 N315 H324 V325 D331 N332F168-F328 HydrophobicContact CE1-CD1 4.27Å; F168-F328 AromaticContact CE1-CE1 3.55Å; F168-F328 HydrophobicContact CE1-CE1 3.55Å; F168-F328 AromaticContact CZ-CE1 3.9Å; F168-F328 HydrophobicContact CZ-CE1 3.9Å; N315-F328 HydrophobicContact CB-CE1 4.25Å; N315-F328 HydrophobicContact CB-CZ 4.17Å; N315-F328 WeakPolarHBondContact OD1-CZ 3.35Å; H324-F328 WeakPolarHBondContact O-CB 3.32Å; H324-F328 PolarHBondContact O-N 3.15Å; V325-F328 WeakPolarHBondContact O-CB 3.16Å; V325-F328 PolarHBondContact O-N 3.31Å; V325-F328 VanDerWaalsContact O-N 3.16Å; F328-D331 PolarHBondContact O-N 2.9Å; F328-N332 WeakPolarHBondContact CD2-ND2 3.39Å; F328-N332 HydrophobicContact CE1-CB 4.44Å; F328-N332 WeakPolarHBondContact CE2-ND2 3.32Å; F328-N332 HydrophobicContact CZ-CB 4.31Å; F328-N332 WeakPolarHBondContact O-CB 3.33Å; F328-N332 PolarHBondContact O-N 2.74Å; F328-N332 PolarHBondContact O-ND2 3.22Å
329D85.2Confident83.5Confident0 Ų052.4 Ų52.40%024%0.243CC..Iπ-helixtrans-65.1-41.4178-67.1-11.6000112.6Q91 N185 F257 V325 F326 K327 F333Q91-D329 PolarHBondContact NE2-OD1 3.25Å; Q91-D329 PolarHBondContact OE1-OD1 2.77Å; Q91-D329 PolarHBondContact OE1-OD2 2.98Å; N185-D329 HydrophobicContact CB-CB 4.02Å; N185-D329 WeakPolarHBondContact CB-OD2 3.26Å; F257-D329 HydrophobicContact CZ-CB 4.46Å; V325-D329 PolarHBondContact O-N 2.82Å; F326-D329 PolarHBondContact O-N 2.82Å; K327-D329 VanDerWaalsContact C-N 3.32Å; K327-D329 PolarHBondContact O-N 2.84Å; D329-F333 WeakPolarHBondContact O-CB 3.34Å; D329-F333 PolarHBondContact O-N 3.11Å
330E78.8Confident83.3Confident67 Ų6752.6 Ų52.631%0.31324%0.244SC..Iπ-helixtrans-65.7-40.1178.7-76.8173.7-162.300112F257 R267 F326 K327F257-E330 HydrophobicContact CE1-CG 4.19Å; R267-E330 IonicContact CZ-OE1 3.1Å; R267-E330 IonicContact NE-OE1 3.99Å; R267-E330 PolarHBondContact NE-OE1 3.4Å; R267-E330 IonicContact NH2-OE1 2.68Å; R267-E330 PolarHBondContact NH2-OE1 2.82Å; F326-E330 WeakPolarHBondContact O-CB 3.36Å; F326-E330 VanDerWaalsContact O-CG 3.31Å; F326-E330 WeakPolarHBondContact O-CG 3.13Å; F326-E330 PolarHBondContact O-N 2.91Å; K327-E330 PolarHBondContact O-N 2.8Å
331D79.9Confident83.1Confident96 Ų9656 Ų5651%0.51326%0.257SS..Iπ-helixtrans-79.4-38.9-176.3-71.9-17.1000112.4K327 F328K327-D331 WeakPolarHBondContact CE-OD2 3.31Å; K327-D331 WeakPolarHBondContact CG-OD2 3.44Å; K327-D331 WeakPolarHBondContact O-CB 3.48Å; K327-D331 PolarHBondContact O-N 3.05Å; F328-D331 PolarHBondContact O-N 2.9Å
332N75.9Confident83.1Confident53 Ų5357.7 Ų57.728%0.28327%0.266SS..Iπ-helixtrans-104.6-61.7-170.5-58.4-74.5000112.6F328 M334 L336F328-N332 WeakPolarHBondContact CD2-ND2 3.39Å; F328-N332 HydrophobicContact CE1-CB 4.44Å; F328-N332 WeakPolarHBondContact CE2-ND2 3.32Å; F328-N332 HydrophobicContact CZ-CB 4.31Å; F328-N332 WeakPolarHBondContact O-CB 3.33Å; F328-N332 PolarHBondContact O-N 2.74Å; F328-N332 PolarHBondContact O-ND2 3.22Å; N332-M334 PolarHBondContact O-N 3.16Å; N332-L336 WeakPolarHBondContact O-CD1 3.38Å; N332-L336 WeakPolarHBondContact O-CG 3.2Å; N332-L336 PolarHBondContact O-N 2.85Å
333F73.4Confident83.2Confident6 Ų659.6 Ų59.63%0.02628%0.275CS..Iπ-helixtrans-62.2-44.7-164.3176.3-120.6000112.9T166 F168 D184 F257 D329 R335 L336 R337T166-F333 HydrophobicContact CG2-CE2 4.25Å; T166-F333 WeakPolarHBondContact O-CE2 3.41Å; T166-F333 VanDerWaalsContact O-CZ 3.27Å; T166-F333 WeakPolarHBondContact O-CZ 3.43Å; F168-F333 HydrophobicContact CD2-CB 3.95Å; F168-F333 HydrophobicContact CD2-CD1 4.09Å; F168-F333 AromaticContact CD2-CD2 3.13Å; F168-F333 HydrophobicContact CD2-CD2 3.13Å; F168-F333 HydrophobicContact CD2-CE1 4.36Å; F168-F333 AromaticContact CD2-CE2 3.43Å; F168-F333 HydrophobicContact CD2-CE2 3.43Å; F168-F333 VanDerWaalsContact CD2-CE2 3.43Å; F168-F333 AromaticContact CD2-CG 3.44Å; F168-F333 HydrophobicContact CD2-CG 3.44Å; F168-F333 VanDerWaalsContact CD2-CG 3.44Å; F168-F333 HydrophobicContact CD2-CZ 4.03Å; F168-F333 HydrophobicContact CE2-CB 3.8Å; F168-F333 AromaticContact CE2-CD2 3.12Å; F168-F333 HydrophobicContact CE2-CD2 3.12Å; F168-F333 AromaticContact CE2-CE2 3.76Å; F168-F333 HydrophobicContact CE2-CE2 3.76Å; F168-F333 AromaticContact CE2-CG 3.63Å; F168-F333 HydrophobicContact CE2-CG 3.63Å; F168-F333 HydrophobicContact CG-CD2 4.35Å; F168-F333 HydrophobicContact CG-CG 4.33Å; F168-F333 HydrophobicContact CZ-CB 4.37Å; F168-F333 HydrophobicContact CZ-CD2 4.33Å; D184-F333 HydrophobicContact CB-CE1 3.68Å; D184-F333 HydrophobicContact CB-CZ 4.33Å; D184-F333 WeakPolarHBondContact OD1-CE1 3.13Å; D184-F333 VanDerWaalsContact OD1-CZ 3.27Å; D184-F333 WeakPolarHBondContact OD1-CZ 3.3Å; F257-F333 HydrophobicContact CE2-CD1 4.43Å; D329-F333 WeakPolarHBondContact O-CB 3.34Å; D329-F333 PolarHBondContact O-N 3.11Å; F333-R335 PolarHBondContact O-N 3.2Å; F333-L336 PolarHBondContact O-N 2.97Å; F333-R337 HydrophobicContact CE2-CB 4.38Å; F333-R337 HydrophobicContact CZ-CB 4.46Å; F333-R337 HydrophobicContact CZ-CG 4.44Å; F333-R337 PolarHBondContact O-N 3.1Å
334M64.9Low83.5Confident53 Ų5358.3 Ų58.326%0.26127%0.268SS..Hα-helixtrans-68.5-38.8-169.5-79.9-54.8-58.200114.6F257 N332 L336F257-M334 HydrophobicContact CB-CE 3.18Å; F257-M334 HydrophobicContact CB-CG 4.29Å; F257-M334 HydrophobicContact CB-SD 3.55Å; F257-M334 VanDerWaalsContact CB-SD 3.55Å; F257-M334 HydrophobicContact CD1-CE 4.09Å; F257-M334 HydrophobicContact CD1-CG 3.44Å; F257-M334 VanDerWaalsContact CD1-CG 3.44Å; F257-M334 HydrophobicContact CD1-SD 3.78Å; F257-M334 HydrophobicContact CD2-CE 3.93Å; F257-M334 HydrophobicContact CD2-CG 3.62Å; F257-M334 HydrophobicContact CD2-SD 2.98Å; F257-M334 WeakPolarHBondContact CD2-SD 3.24Å; F257-M334 HydrophobicContact CE1-CG 3.39Å; F257-M334 HydrophobicContact CE1-SD 4.15Å; F257-M334 HydrophobicContact CE2-CG 3.46Å; F257-M334 VanDerWaalsContact CE2-CG 3.46Å; F257-M334 HydrophobicContact CE2-SD 3.32Å; F257-M334 WeakPolarHBondContact CE2-SD 3.33Å; F257-M334 HydrophobicContact CG-CE 3.55Å; F257-M334 HydrophobicContact CG-CG 3.58Å; F257-M334 HydrophobicContact CG-SD 3.2Å; F257-M334 WeakPolarHBondContact CG-SD 3.12Å; F257-M334 HydrophobicContact CZ-CG 3.36Å; F257-M334 HydrophobicContact CZ-SD 3.92Å; N332-M334 PolarHBondContact O-N 3.16Å; M334-L336 VanDerWaalsContact C-N 3.33Å
335R69.7Low83.8Confident193 Ų19359.6 Ų59.673%0.72827%0.274SS*.Hα-helixtrans-69-38.1175.7179.6-179.8161.2179.6-7110.7F333 I339F333-R335 PolarHBondContact O-N 3.2Å; R335-I339 HydrophobicContact CG-CD1 4.33Å; R335-I339 WeakPolarHBondContact O-CD1 3.33Å; R335-I339 WeakPolarHBondContact O-CG1 3.29Å
336L77.6Confident84Confident32 Ų3268.8 Ų68.817%0.16831%0.309CS..Hα-helixtrans-72.6-38.6-176.3-65.4171.8000111.7A54 D55 I58 N332 F333 M334 E338 I339 E340A54-L336 HydrophobicContact CB-CB 3.8Å; A54-L336 HydrophobicContact CB-CD2 3.69Å; A54-L336 HydrophobicContact CB-CG 4.33Å; A54-L336 VanDerWaalsContact CB-O 3.24Å; A54-L336 WeakPolarHBondContact CB-O 3.15Å; D55-L336 HydrophobicContact CB-CD2 4.38Å; I58-L336 HydrophobicContact CG2-CD1 4.43Å; N332-L336 WeakPolarHBondContact O-CD1 3.38Å; N332-L336 WeakPolarHBondContact O-CG 3.2Å; N332-L336 PolarHBondContact O-N 2.85Å; F333-L336 PolarHBondContact O-N 2.97Å; M334-L336 VanDerWaalsContact C-N 3.33Å; L336-E338 VanDerWaalsContact C-N 3.34Å; L336-E338 PolarHBondContact O-N 3.06Å; L336-I339 PolarHBondContact O-N 2.87Å; L336-I339 VanDerWaalsContact O-N 3.08Å; L336-E340 WeakPolarHBondContact O-CB 3.17Å; L336-E340 PolarHBondContact O-N 2.79Å
337R82.9Confident84.4Confident69 Ų6970.3 Ų70.326%0.2632%0.316SS..Hα-helixtrans-57.2-42.7-178.5-170.9176.9-176168.62.9113.7H167 D184 F333 I339 E340 K341H167-R337 PolarHBondContact CE1-NH2 2.85Å; D184-R337 IonicContact OD2-CZ 2.78Å; D184-R337 IonicContact OD2-NH1 3.44Å; D184-R337 PolarHBondContact OD2-NH1 3.02Å; D184-R337 IonicContact OD2-NH2 3.49Å; F333-R337 HydrophobicContact CE2-CB 4.38Å; F333-R337 HydrophobicContact CZ-CB 4.46Å; F333-R337 HydrophobicContact CZ-CG 4.44Å; F333-R337 PolarHBondContact O-N 3.1Å; R337-I339 VanDerWaalsContact C-N 3.34Å; R337-E340 PolarHBondContact O-N 2.75Å; R337-K341 WeakPolarHBondContact O-CB 3.09Å; R337-K341 PolarHBondContact O-N 2.76Å
338E83.5Confident84.9Confident139 Ų13967.3 Ų67.365%0.6531%0.306SS*.Hα-helixtrans-69.4-34.3179.5-170.3163.9-167.400112L336 N342L336-E338 VanDerWaalsContact C-N 3.34Å; L336-E338 PolarHBondContact O-N 3.06Å; E338-N342 WeakPolarHBondContact O-CB 3.38Å; E338-N342 VanDerWaalsContact O-CG 3.3Å; E338-N342 PolarHBondContact O-N 3.25Å; E338-N342 PolarHBondContact O-ND2 3.27Å
339I90.9Very high85.4Confident70 Ų7070.9 Ų70.936%0.35933%0.329SS..Hα-helixtrans-68.7-46.2174.7-58.8169.9000110A54 R335 L336 R337 K341 N342 M343A54-I339 HydrophobicContact CB-CB 3.86Å; A54-I339 HydrophobicContact CB-CG2 3.96Å; R335-I339 HydrophobicContact CG-CD1 4.33Å; R335-I339 WeakPolarHBondContact O-CD1 3.33Å; R335-I339 WeakPolarHBondContact O-CG1 3.29Å; L336-I339 PolarHBondContact O-N 2.87Å; L336-I339 VanDerWaalsContact O-N 3.08Å; R337-I339 VanDerWaalsContact C-N 3.34Å; I339-K341 VanDerWaalsContact C-N 3.33Å; I339-K341 PolarHBondContact O-N 2.79Å; I339-N342 PolarHBondContact O-N 2.91Å; I339-M343 WeakPolarHBondContact O-CB 3.5Å; I339-M343 PolarHBondContact O-N 3.15Å
340E91.7Very high85.8Confident4 Ų475.9 Ų75.92%0.01935%0.352CS..Hα-helixtrans-56.5-47.1176.3-177.6-175.9-120.600110.9F52 A54 K95 Y165 T166 L336 R337 M343 K344F52-E340 HydrophobicContact CD2-CG 3.63Å; F52-E340 HydrophobicContact CE2-CG 3.62Å; A54-E340 HydrophobicContact CB-CB 4.17Å; K95-E340 WeakPolarHBondContact CE-OE1 3.42Å; K95-E340 IonicContact NZ-OE1 3.27Å; K95-E340 PolarHBondContact NZ-OE1 2.79Å; Y165-E340 HydrophobicContact CD1-CG 4.45Å; T166-E340 PolarHBondContact N-OE2 3.25Å; T166-E340 PolarHBondContact OG1-OE1 3.44Å; L336-E340 WeakPolarHBondContact O-CB 3.17Å; L336-E340 PolarHBondContact O-N 2.79Å; R337-E340 PolarHBondContact O-N 2.75Å; E340-M343 PolarHBondContact O-N 3.29Å; E340-K344 PolarHBondContact O-N 3.19Å
341K90.7Very high86.6Confident99 Ų9977 Ų7743%0.4336%0.356SS..Hα-helixtrans-60.1-49.2177.3-174.3176.4-179.9179.40111.9Y165 R337 I339 M343 K344 E345Y165-K341 HydrophobicContact CE1-CB 4.09Å; Y165-K341 HydrophobicContact CE1-CG 4.09Å; R337-K341 WeakPolarHBondContact O-CB 3.09Å; R337-K341 PolarHBondContact O-N 2.76Å; I339-K341 VanDerWaalsContact C-N 3.33Å; I339-K341 PolarHBondContact O-N 2.79Å; K341-M343 VanDerWaalsContact C-N 3.29Å; K341-M343 PolarHBondContact O-N 2.89Å; K341-K344 PolarHBondContact O-N 2.88Å; K341-E345 VanDerWaalsContact CE-OE1 3.26Å; K341-E345 WeakPolarHBondContact CE-OE1 3.41Å; K341-E345 WeakPolarHBondContact O-CG 3.23Å; K341-E345 PolarHBondContact O-N 2.9Å
342N92Very high87.4Confident69 Ų6980.9 Ų80.937%0.36936%0.364SS..Hα-helixtrans-60.1-38.7176.6-78.8-49.8000112.2E338 I339 R346E338-N342 WeakPolarHBondContact O-CB 3.38Å; E338-N342 VanDerWaalsContact O-CG 3.3Å; E338-N342 PolarHBondContact O-N 3.25Å; E338-N342 PolarHBondContact O-ND2 3.27Å; I339-N342 PolarHBondContact O-N 2.91Å; N342-R346 WeakPolarHBondContact O-CB 3.23Å; N342-R346 VanDerWaalsContact O-CG 3.22Å; N342-R346 WeakPolarHBondContact O-CG 3.41Å; N342-R346 PolarHBondContact O-N 3.32Å; N342-R346 VanDerWaalsContact O-N 3.1Å
343M92.8Very high88.4Confident51 Ų5182.7 Ų82.725%0.25137%0.372SS..Hα-helixtrans-64.9-45.6175.6179.5148.1172.100111.3F52 Y53 I339 E340 K341 R346 M347F52-M343 HydrophobicContact CB-CG 4.29Å; Y53-M343 HydrophobicContact CD1-CE 3.99Å; Y53-M343 HydrophobicContact CD2-CE 4.15Å; Y53-M343 HydrophobicContact CD2-SD 4.07Å; Y53-M343 HydrophobicContact CE1-CE 3.63Å; Y53-M343 HydrophobicContact CE2-CE 3.8Å; Y53-M343 HydrophobicContact CE2-SD 4.08Å; Y53-M343 HydrophobicContact CG-CE 4.26Å; Y53-M343 HydrophobicContact CG-SD 4.4Å; Y53-M343 WeakPolarHBondContact O-CB 3.47Å; I339-M343 WeakPolarHBondContact O-CB 3.5Å; I339-M343 PolarHBondContact O-N 3.15Å; E340-M343 PolarHBondContact O-N 3.29Å; K341-M343 VanDerWaalsContact C-N 3.29Å; K341-M343 PolarHBondContact O-N 2.89Å; M343-R346 PolarHBondContact O-N 2.82Å; M343-M347 HydrophobicContact CE-SD 4Å; M343-M347 HydrophobicContact CG-SD 4.22Å; M343-M347 WeakPolarHBondContact O-CB 3.45Å; M343-M347 WeakPolarHBondContact O-CG 3.28Å; M343-M347 PolarHBondContact O-N 3.35Å
344K93.1Very high89.5Confident13 Ų1388.4 Ų88.46%0.05740%0.397CS..Hα-helixtrans-59.8-48177-175.452.4159.7730112.2F52 E164 Y165 E340 K341 R346 M347 D348F52-K344 HydrophobicContact CD1-CD 3.68Å; F52-K344 HydrophobicContact CD2-CB 3.71Å; F52-K344 HydrophobicContact CD2-CD 4.1Å; F52-K344 HydrophobicContact CD2-CG 4.23Å; F52-K344 HydrophobicContact CE1-CD 3.66Å; F52-K344 VanDerWaalsContact CE1-CE 3.49Å; F52-K344 HydrophobicContact CE1-CG 4.38Å; F52-K344 HydrophobicContact CE2-CB 3.78Å; F52-K344 HydrophobicContact CE2-CD 4.07Å; F52-K344 HydrophobicContact CE2-CG 3.99Å; F52-K344 HydrophobicContact CG-CB 4.22Å; F52-K344 HydrophobicContact CG-CD 3.87Å; F52-K344 HydrophobicContact CZ-CB 4.33Å; F52-K344 HydrophobicContact CZ-CD 3.82Å; F52-K344 HydrophobicContact CZ-CG 4.03Å; E164-K344 WeakPolarHBondContact OE2-CE 3.27Å; E164-K344 IonicContact OE2-NZ 3.62Å; E164-K344 PolarHBondContact OE2-NZ 3.3Å; Y165-K344 HydrophobicContact CE1-CB 4.03Å; Y165-K344 HydrophobicContact CE1-CG 4.16Å; E340-K344 PolarHBondContact O-N 3.19Å; K341-K344 PolarHBondContact O-N 2.88Å; K344-R346 VanDerWaalsContact C-N 3.33Å; K344-R346 PolarHBondContact O-N 3.28Å; K344-M347 WeakPolarHBondContact O-CB 3.45Å; K344-M347 PolarHBondContact O-N 3.1Å; K344-M347 VanDerWaalsContact O-N 3.12Å; K344-D348 IonicContact NZ-OD1 3.39Å; K344-D348 PolarHBondContact NZ-OD1 3.21Å; K344-D348 IonicContact NZ-OD2 2.74Å; K344-D348 PolarHBondContact NZ-OD2 3.14Å; K344-D348 PolarHBondContact O-N 2.82Å
345E93.5Very high91Very high90 Ų9093.5 Ų93.542%0.42141%0.413SS..Hα-helixtrans-58.6-45.1178.4-73.4178.4-174.500111.5K341 M347 D348 V349K341-E345 VanDerWaalsContact CE-OE1 3.26Å; K341-E345 WeakPolarHBondContact CE-OE1 3.41Å; K341-E345 WeakPolarHBondContact O-CG 3.23Å; K341-E345 PolarHBondContact O-N 2.9Å; E345-M347 VanDerWaalsContact C-N 3.35Å; E345-M347 PolarHBondContact O-N 2.91Å; E345-D348 PolarHBondContact O-N 3.14Å; E345-V349 VanDerWaalsContact O-CG2 3.32Å; E345-V349 WeakPolarHBondContact O-CG2 3.44Å; E345-V349 PolarHBondContact O-N 3.36Å
346R94Very high92.3Very high193 Ų19388.2 Ų88.273%0.72840%0.4SS*.Hα-helixtrans-60.3-44.2174.7-72.3171.3-175.1-167.13.2111.8N342 M343 K344 V349 Q350N342-R346 WeakPolarHBondContact O-CB 3.23Å; N342-R346 VanDerWaalsContact O-CG 3.22Å; N342-R346 WeakPolarHBondContact O-CG 3.41Å; N342-R346 PolarHBondContact O-N 3.32Å; N342-R346 VanDerWaalsContact O-N 3.1Å; M343-R346 PolarHBondContact O-N 2.82Å; K344-R346 VanDerWaalsContact C-N 3.33Å; K344-R346 PolarHBondContact O-N 3.28Å; R346-V349 PolarHBondContact O-N 3.1Å; R346-Q350 WeakPolarHBondContact O-CB 3.21Å; R346-Q350 PolarHBondContact O-N 3.1Å
347M93Very high93.2Very high37 Ų3790.9 Ų90.918%0.18241%0.413CS..Hα-helixtrans-64.1-41.7178.4-76.3-175.258.300112.3D51 F52 M343 K344 E345 Q350 K351D51-M347 WeakPolarHBondContact O-CE 3.23Å; F52-M347 HydrophobicContact CB-CE 4.41Å; F52-M347 HydrophobicContact CB-SD 3.56Å; F52-M347 VanDerWaalsContact CB-SD 3.56Å; M343-M347 HydrophobicContact CE-SD 4Å; M343-M347 HydrophobicContact CG-SD 4.22Å; M343-M347 WeakPolarHBondContact O-CB 3.45Å; M343-M347 WeakPolarHBondContact O-CG 3.28Å; M343-M347 PolarHBondContact O-N 3.35Å; K344-M347 WeakPolarHBondContact O-CB 3.45Å; K344-M347 PolarHBondContact O-N 3.1Å; K344-M347 VanDerWaalsContact O-N 3.12Å; E345-M347 VanDerWaalsContact C-N 3.35Å; E345-M347 PolarHBondContact O-N 2.91Å; M347-Q350 PolarHBondContact O-N 3.47Å; M347-K351 WeakPolarHBondContact O-CB 3.49Å; M347-K351 WeakPolarHBondContact O-CG 3.35Å; M347-K351 PolarHBondContact O-N 3.44Å
348D93.2Very high93.9Very high66 Ų6696 Ų9635%0.35343%0.433SS..Hα-helixtrans-67.2-41.8178.9-73.5-18.6000111.7K344 E345 Q350 K351 R352K344-D348 IonicContact NZ-OD1 3.39Å; K344-D348 PolarHBondContact NZ-OD1 3.21Å; K344-D348 IonicContact NZ-OD2 2.74Å; K344-D348 PolarHBondContact NZ-OD2 3.14Å; K344-D348 PolarHBondContact O-N 2.82Å; E345-D348 PolarHBondContact O-N 3.14Å; D348-Q350 VanDerWaalsContact C-N 3.33Å; D348-Q350 PolarHBondContact O-N 2.95Å; D348-K351 PolarHBondContact O-N 3.04Å; D348-R352 WeakPolarHBondContact O-CB 3.32Å; D348-R352 PolarHBondContact O-N 3.18Å
349V95.9Very high94.6Very high88 Ų8893.3 Ų93.353%0.53342%0.423SS..Hα-helixtrans-59.5-45.6172.11710000110.4E345 R346 R352 I353E345-V349 VanDerWaalsContact O-CG2 3.32Å; E345-V349 WeakPolarHBondContact O-CG2 3.44Å; E345-V349 PolarHBondContact O-N 3.36Å; R346-V349 PolarHBondContact O-N 3.1Å; V349-R352 PolarHBondContact O-N 3.24Å; V349-I353 HydrophobicContact CG1-CD1 3.85Å; V349-I353 HydrophobicContact CG1-CG1 4.5Å; V349-I353 WeakPolarHBondContact O-CG1 3.17Å; V349-I353 PolarHBondContact O-N 2.52Å
350Q95.2Very high94.9Very high106 Ų10699.7 Ų99.750%0.49544%0.442SS..Hα-helixtrans-64.6-42.5178.4-162.7-17224.400112.2R346 M347 D348 R352 I353 K354R346-Q350 WeakPolarHBondContact O-CB 3.21Å; R346-Q350 PolarHBondContact O-N 3.1Å; M347-Q350 PolarHBondContact O-N 3.47Å; D348-Q350 VanDerWaalsContact C-N 3.33Å; D348-Q350 PolarHBondContact O-N 2.95Å; Q350-R352 VanDerWaalsContact C-N 3.33Å; Q350-R352 PolarHBondContact O-N 3.45Å; Q350-I353 PolarHBondContact O-N 3.17Å; Q350-K354 HydrophobicContact CG-CD 4.48Å; Q350-K354 WeakPolarHBondContact O-CB 3.38Å; Q350-K354 WeakPolarHBondContact O-CG 3.47Å; Q350-K354 PolarHBondContact O-N 2.91Å
351K94.5Very high95.1Very high91 Ų91106.2 Ų106.240%0.39647%0.471SS..Hα-helixtrans-60.2-43174.4-77.7175.6-179.5176.10110.6M347 D348 K354 R355M347-K351 WeakPolarHBondContact O-CB 3.49Å; M347-K351 WeakPolarHBondContact O-CG 3.35Å; M347-K351 PolarHBondContact O-N 3.44Å; D348-K351 PolarHBondContact O-N 3.04Å; K351-K354 PolarHBondContact O-N 2.88Å; K351-R355 WeakPolarHBondContact O-CB 3.31Å; K351-R355 PolarHBondContact O-N 3.03Å
352R96.2Very high95.4Very high176 Ų176105 Ų10566%0.66447%0.469SS*.Hα-helixtrans-64-45.2177.2-171.3176.1-178.5-176-0.4112.2D348 V349 Q350 R355 N356D348-R352 WeakPolarHBondContact O-CB 3.32Å; D348-R352 PolarHBondContact O-N 3.18Å; V349-R352 PolarHBondContact O-N 3.24Å; Q350-R352 VanDerWaalsContact C-N 3.33Å; Q350-R352 PolarHBondContact O-N 3.45Å; R352-R355 PolarHBondContact O-N 2.7Å; R352-N356 VanDerWaalsContact O-CG 3.25Å; R352-N356 PolarHBondContact O-N 2.75Å; R352-N356 PolarHBondContact O-OD1 2.93Å
353I97.3Very high95.7Very high92 Ų92104.5 Ų104.547%0.47247%0.474SS..Hα-helixtrans-61.4-47.5175.9-68.3167.6000110.7V349 Q350 R355 N356 I357V349-I353 HydrophobicContact CG1-CD1 3.85Å; V349-I353 HydrophobicContact CG1-CG1 4.5Å; V349-I353 WeakPolarHBondContact O-CG1 3.17Å; V349-I353 PolarHBondContact O-N 2.52Å; Q350-I353 PolarHBondContact O-N 3.17Å; I353-R355 VanDerWaalsContact C-N 3.33Å; I353-R355 PolarHBondContact O-N 3.11Å; I353-N356 PolarHBondContact O-N 2.96Å; I353-I357 HydrophobicContact CG2-CD1 3.85Å; I353-I357 WeakPolarHBondContact O-CG1 3.2Å; I353-I357 PolarHBondContact O-N 3.43Å
354K97Very high95.9Very high126 Ų126106.2 Ų106.255%0.54848%0.482SS..Hα-helixtrans-59.8-41.9177.7-76175.5179.3172.50112.1Q350 K351 I357 R358Q350-K354 HydrophobicContact CG-CD 4.48Å; Q350-K354 WeakPolarHBondContact O-CB 3.38Å; Q350-K354 WeakPolarHBondContact O-CG 3.47Å; Q350-K354 PolarHBondContact O-N 2.91Å; K351-K354 PolarHBondContact O-N 2.88Å; K354-I357 PolarHBondContact O-N 3.27Å; K354-R358 WeakPolarHBondContact O-CB 2.97Å; K354-R358 PolarHBondContact O-N 3.26Å
355R96.8Very high96.1Very high159 Ų159112.4 Ų112.460%0.651%0.509SS*.Hα-helixtrans-60.9-50.8175-170.6-174.7-62.9158.20.3111K351 R352 I353 I357 R358 D359K351-R355 WeakPolarHBondContact O-CB 3.31Å; K351-R355 PolarHBondContact O-N 3.03Å; R352-R355 PolarHBondContact O-N 2.7Å; I353-R355 VanDerWaalsContact C-N 3.33Å; I353-R355 PolarHBondContact O-N 3.11Å; R355-I357 VanDerWaalsContact C-N 3.31Å; R355-I357 PolarHBondContact O-N 2.85Å; R355-R358 WeakPolarHBondContact O-CB 3.32Å; R355-R358 PolarHBondContact O-N 3.15Å; R355-D359 VanDerWaalsContact O-CG 3.27Å; R355-D359 PolarHBondContact O-N 3.16Å
356N96.8Very high96.2Very high83 Ų83117 Ų11744%0.44452%0.522SS..Hα-helixtrans-58.5-40.2178.3-69.8-8.3000112.7R352 I353 R360R352-N356 VanDerWaalsContact O-CG 3.25Å; R352-N356 PolarHBondContact O-N 2.75Å; R352-N356 PolarHBondContact O-OD1 2.93Å; I353-N356 PolarHBondContact O-N 2.96Å; N356-R360 WeakPolarHBondContact O-CB 3.44Å; N356-R360 WeakPolarHBondContact O-CG 3.09Å; N356-R360 PolarHBondContact O-N 3.26Å
357I97.3Very high96.3Very high88 Ų88115.4 Ų115.445%0.45152%0.516SS..Hα-helixtrans-64.9-44.4175.4-68.2168.5000110.9I353 K354 R355 K361I353-I357 HydrophobicContact CG2-CD1 3.85Å; I353-I357 WeakPolarHBondContact O-CG1 3.2Å; I353-I357 PolarHBondContact O-N 3.43Å; K354-I357 PolarHBondContact O-N 3.27Å; R355-I357 VanDerWaalsContact C-N 3.31Å; R355-I357 PolarHBondContact O-N 2.85Å; I357-K361 HydrophobicContact CG2-CD 4.38Å; I357-K361 WeakPolarHBondContact O-CG 3.36Å; I357-K361 PolarHBondContact O-N 3.05Å
358R97.1Very high96.5Very high177 Ų177119 Ų11967%0.66853%0.532SS*.Hα-helixtrans-62-44.1177.2178.1179.9-87.6-179.5-5.4111.1K354 R355 K361 N362K354-R358 WeakPolarHBondContact O-CB 2.97Å; K354-R358 PolarHBondContact O-N 3.26Å; R355-R358 WeakPolarHBondContact O-CB 3.32Å; R355-R358 PolarHBondContact O-N 3.15Å; R358-K361 PolarHBondContact O-N 2.64Å; R358-N362 WeakPolarHBondContact O-CB 3.43Å; R358-N362 VanDerWaalsContact O-CG 3.31Å; R358-N362 PolarHBondContact O-N 3.37Å
359D97Very high96.7Very high82 Ų82118.8 Ų118.844%0.43954%0.54SS..Hα-helixtrans-66.9-41.8-178.7-65.4-17.7000111.5R355 K361 N362 A363R355-D359 VanDerWaalsContact O-CG 3.27Å; R355-D359 PolarHBondContact O-N 3.16Å; D359-K361 PolarHBondContact O-N 2.68Å; D359-N362 PolarHBondContact O-N 3.28Å; D359-A363 WeakPolarHBondContact O-CB 3.33Å; D359-A363 PolarHBondContact O-N 3.04Å
360R97.1Very high96.7Very high203 Ų203121 Ų12177%0.76654%0.544SS*.Hα-helixtrans-61.4-43172.7-72.7-179.787.2179.46.9112.1N356 N362 A363 E364N356-R360 WeakPolarHBondContact O-CB 3.44Å; N356-R360 WeakPolarHBondContact O-CG 3.09Å; N356-R360 PolarHBondContact O-N 3.26Å; R360-N362 VanDerWaalsContact C-N 3.35Å; R360-N362 PolarHBondContact O-N 3.01Å; R360-A363 PolarHBondContact O-N 3.02Å; R360-E364 WeakPolarHBondContact O-CB 3.33Å; R360-E364 PolarHBondContact O-N 2.73Å
361K97.3Very high96.7Very high142 Ų142121 Ų12162%0.61755%0.547SS*.Hα-helixtrans-63-40.2175.6-76.2-177.6178.3-175.30112.1I357 R358 D359 K365I357-K361 HydrophobicContact CG2-CD 4.38Å; I357-K361 WeakPolarHBondContact O-CG 3.36Å; I357-K361 PolarHBondContact O-N 3.05Å; R358-K361 PolarHBondContact O-N 2.64Å; D359-K361 PolarHBondContact O-N 2.68Å; K361-K365 WeakPolarHBondContact O-CG 3.4Å; K361-K365 PolarHBondContact O-N 3.27Å
362N97.1Very high96.8Very high72 Ų72123.6 Ų123.639%0.38556%0.559SS.*Hα-helixtrans-69-39.9177.8-73.6-15000111.9R358 D359 R360 K365 R366R358-N362 WeakPolarHBondContact O-CB 3.43Å; R358-N362 VanDerWaalsContact O-CG 3.31Å; R358-N362 PolarHBondContact O-N 3.37Å; D359-N362 PolarHBondContact O-N 3.28Å; R360-N362 VanDerWaalsContact C-N 3.35Å; R360-N362 PolarHBondContact O-N 3.01Å; N362-K365 PolarHBondContact O-N 3.46Å; N362-R366 WeakPolarHBondContact O-CG 3.37Å; N362-R366 PolarHBondContact O-N 3.27Å
363A97.1Very high96.7Very high59 Ų59123 Ų12349%0.48856%0.561SS.*Hα-helixtrans-63.1-43.9174.900000111.8D359 R360 R366 R367D359-A363 WeakPolarHBondContact O-CB 3.33Å; D359-A363 PolarHBondContact O-N 3.04Å; R360-A363 PolarHBondContact O-N 3.02Å; A363-R366 PolarHBondContact O-N 3.48Å; A363-R367 PolarHBondContact O-N 3.32Å
364E96.9Very high96.5Very high88 Ų88124.4 Ų124.441%0.41157%0.565SS.*Hα-helixtrans-63.6-42.6176.7-176.557.2-154.900111.8R360 R366 R367 Q368R360-E364 WeakPolarHBondContact O-CB 3.33Å; R360-E364 PolarHBondContact O-N 2.73Å; E364-R366 VanDerWaalsContact C-N 3.33Å; E364-R366 PolarHBondContact O-N 2.8Å; E364-R367 PolarHBondContact O-N 3.03Å; E364-Q368 WeakPolarHBondContact O-CG 3.33Å; E364-Q368 PolarHBondContact O-N 3.5Å; E364-Q368 PolarHBondContact OE1-NE2 3.41Å
365K97Very high96.4Very high143 Ų143127 Ų12762%0.62257%0.572SS**Hα-helixtrans-59.6-41.6173.6-78.3-178.1178.1-1740112.6K361 N362 Q368 A369K361-K365 WeakPolarHBondContact O-CG 3.4Å; K361-K365 PolarHBondContact O-N 3.27Å; N362-K365 PolarHBondContact O-N 3.46Å; K365-Q368 PolarHBondContact O-N 3.2Å; K365-A369 WeakPolarHBondContact O-CB 3.12Å; K365-A369 PolarHBondContact O-N 2.88Å
366R96.8Very high96.3Very high186 Ų186125.6 Ų125.670%0.70257%0.57SS**Hα-helixtrans-63.1-45.7175.9-73.7176.6-178.9-173.10111N362 A363 E364 Q368 A369 E370N362-R366 WeakPolarHBondContact O-CG 3.37Å; N362-R366 PolarHBondContact O-N 3.27Å; A363-R366 PolarHBondContact O-N 3.48Å; E364-R366 VanDerWaalsContact C-N 3.33Å; E364-R366 PolarHBondContact O-N 2.8Å; R366-Q368 PolarHBondContact O-N 2.94Å; R366-A369 PolarHBondContact O-N 2.76Å; R366-E370 PolarHBondContact O-N 2.71Å
367R96.6Very high96.2Very high159 Ų159125.9 Ų125.960%0.657%0.571SS**Hα-helixtrans-60.6-42.4176.9-170.2179.6179.3176.50.7112.5A363 E364 E370 L371A363-R367 PolarHBondContact O-N 3.32Å; E364-R367 PolarHBondContact O-N 3.03Å; R367-E370 PolarHBondContact O-N 3.24Å; R367-L371 HydrophobicContact CG-CD1 4.3Å; R367-L371 WeakPolarHBondContact O-CB 3.19Å; R367-L371 WeakPolarHBondContact O-CG 3.38Å; R367-L371 PolarHBondContact O-N 3.49Å
368Q96.4Very high96Very high112 Ų112124.4 Ų124.452%0.52357%0.566SS.*Hα-helixtrans-66.2-38.1176.2-71.8179.48.900112.5E364 K365 R366 K372E364-Q368 WeakPolarHBondContact O-CG 3.33Å; E364-Q368 PolarHBondContact O-N 3.5Å; E364-Q368 PolarHBondContact OE1-NE2 3.41Å; K365-Q368 PolarHBondContact O-N 3.2Å; R366-Q368 PolarHBondContact O-N 2.94Å; Q368-K372 WeakPolarHBondContact O-CB 3.47Å; Q368-K372 PolarHBondContact O-N 2.76Å
369A96.3Very high95.8Very high62 Ų62120.1 Ų120.151%0.51256%0.556SS.*Hα-helixtrans-65.1-41.4174.800000111.9K365 R366 K372 K373K365-A369 WeakPolarHBondContact O-CB 3.12Å; K365-A369 PolarHBondContact O-N 2.88Å; R366-A369 PolarHBondContact O-N 2.76Å; A369-K372 PolarHBondContact O-N 3.39Å; A369-K373 PolarHBondContact O-N 3.46Å
370E96Very high95.5Very high135 Ų135121.7 Ų121.763%0.63156%0.561SS**Hα-helixtrans-64.3-46.1174.7-76.2175.1176.200112.2R366 R367 K372 K373 H374R366-E370 PolarHBondContact O-N 2.71Å; R367-E370 PolarHBondContact O-N 3.24Å; E370-K372 VanDerWaalsContact C-N 3.29Å; E370-K372 PolarHBondContact O-N 2.78Å; E370-K373 PolarHBondContact O-N 3.36Å; E370-K373 VanDerWaalsContact O-N 3.13Å; E370-H374 PolarHBondContact O-N 3.46Å
371L96Very high95.2Very high105 Ų105115.8 Ų115.855%0.5554%0.544SS..Hα-helixtrans-58.7-40.7175-78.1166.5000111.8R367 H374 R375R367-L371 HydrophobicContact CG-CD1 4.3Å; R367-L371 WeakPolarHBondContact O-CB 3.19Å; R367-L371 WeakPolarHBondContact O-CG 3.38Å; R367-L371 PolarHBondContact O-N 3.49Å; L371-H374 PolarHBondContact O-N 3.06Å; L371-R375 WeakPolarHBondContact O-CB 3.37Å; L371-R375 PolarHBondContact O-N 3.35Å
372K95.8Very high94.8Very high147 Ų147112.9 Ų112.964%0.63954%0.535SS*.Hα-helixtrans-66.1-38.2176.4-170.1175.5-177.9177.90112.1Q368 A369 E370 K376Q368-K372 WeakPolarHBondContact O-CB 3.47Å; Q368-K372 PolarHBondContact O-N 2.76Å; A369-K372 PolarHBondContact O-N 3.39Å; E370-K372 VanDerWaalsContact C-N 3.29Å; E370-K372 PolarHBondContact O-N 2.78Å; K372-K376 PolarHBondContact O-N 3.18Å; K372-K376 VanDerWaalsContact O-N 3.14Å
373K95.1Very high94.4Very high164 Ų164111.8 Ų111.871%0.71354%0.536SS*.Hα-helixtrans-66.9-43.5174.9-171-178.7178.3-175.30111.2A369 E370 K376 L377A369-K373 PolarHBondContact O-N 3.46Å; E370-K373 PolarHBondContact O-N 3.36Å; E370-K373 VanDerWaalsContact O-N 3.13Å; K373-K376 PolarHBondContact O-N 3.14Å; K373-L377 PolarHBondContact O-N 3.14Å; K373-L377 VanDerWaalsContact O-N 3.1Å
374H93.3Very high93.8Very high121 Ų121115.5 Ų115.556%0.5654%0.543SS*.Hα-helixtrans-64.5-41.7177.7-165.863.4000111.6E370 L371 K376 L377 V378E370-H374 PolarHBondContact O-N 3.46Å; L371-H374 PolarHBondContact O-N 3.06Å; H374-K376 PolarHBondContact O-N 2.64Å; H374-L377 PolarHBondContact O-N 2.68Å; H374-V378 WeakPolarHBondContact O-CG2 3.04Å; H374-V378 PolarHBondContact O-N 3.15Å
375R94.9Very high93.2Very high181 Ų181115.5 Ų115.568%0.68355%0.545SS*.Hα-helixtrans-59.4-45.5174.9-168.8178.1-171.3-160.12.6112.2L371 L377 V378 D379L371-R375 WeakPolarHBondContact O-CB 3.37Å; L371-R375 PolarHBondContact O-N 3.35Å; R375-L377 VanDerWaalsContact C-N 3.33Å; R375-L377 PolarHBondContact O-N 3.34Å; R375-V378 PolarHBondContact O-N 3.03Å; R375-D379 PolarHBondContact O-N 2.86Å
376K94.4Very high92.3Very high129 Ų129114.7 Ų114.756%0.56155%0.547SS*.Hα-helixtrans-58.2-43.7175.2-79.6-171.2170-159.70112.7K372 K373 H374 V378 D379 E380K372-K376 PolarHBondContact O-N 3.18Å; K372-K376 VanDerWaalsContact O-N 3.14Å; K373-K376 PolarHBondContact O-N 3.14Å; H374-K376 PolarHBondContact O-N 2.64Å; K376-V378 VanDerWaalsContact C-N 3.35Å; K376-D379 PolarHBondContact O-N 2.98Å; K376-E380 WeakPolarHBondContact O-CG 3.09Å; K376-E380 PolarHBondContact O-N 2.76Å
377L93.6Very high91.3Very high88 Ų88112.4 Ų112.446%0.46154%0.544SS..Hα-helixtrans-63.4-41.5178.2-176.768.1000111.8K373 H374 R375 E380 I381K373-L377 PolarHBondContact O-N 3.14Å; K373-L377 VanDerWaalsContact O-N 3.1Å; H374-L377 PolarHBondContact O-N 2.68Å; R375-L377 VanDerWaalsContact C-N 3.33Å; R375-L377 PolarHBondContact O-N 3.34Å; L377-E380 PolarHBondContact O-N 3.44Å; L377-I381 HydrophobicContact CD1-CD1 4.48Å; L377-I381 HydrophobicContact CG-CD1 4.08Å; L377-I381 VanDerWaalsContact O-CG1 3.31Å; L377-I381 WeakPolarHBondContact O-CG1 3.46Å; L377-I381 PolarHBondContact O-N 3.1Å
378V93.5Very high89.9Confident57 Ų57110.6 Ų110.635%0.34554%0.542SS..Hα-helixtrans-64-42.4175.5171.70000111H374 R375 K376 E380 I381 N382H374-V378 WeakPolarHBondContact O-CG2 3.04Å; H374-V378 PolarHBondContact O-N 3.15Å; R375-V378 PolarHBondContact O-N 3.03Å; K376-V378 VanDerWaalsContact C-N 3.35Å; V378-E380 VanDerWaalsContact C-N 3.34Å; V378-I381 PolarHBondContact O-N 2.92Å; V378-N382 WeakPolarHBondContact O-CB 3.4Å; V378-N382 VanDerWaalsContact O-CG 3.24Å; V378-N382 PolarHBondContact O-N 3.26Å; V378-N382 PolarHBondContact O-ND2 3.3Å
379D92.9Very high88.3Confident87 Ų87110.6 Ų110.647%0.46555%0.546SS..Hα-helixtrans-63.6-39.1177.1-64.5-24.9000111.4R375 K376 A383R375-D379 PolarHBondContact O-N 2.86Å; K376-D379 PolarHBondContact O-N 2.98Å; D379-A383 PolarHBondContact O-N 3.37Å; D379-A383 VanDerWaalsContact O-N 3.08Å
380E91.9Very high86.5Confident116 Ų116111.4 Ų111.454%0.54255%0.548SS..Hα-helixtrans-64.2-48.1174.4-77.2167-170.500112.1K376 L377 V378 N382 A383 E384K376-E380 WeakPolarHBondContact O-CG 3.09Å; K376-E380 PolarHBondContact O-N 2.76Å; L377-E380 PolarHBondContact O-N 3.44Å; V378-E380 VanDerWaalsContact C-N 3.34Å; E380-N382 VanDerWaalsContact C-N 3.32Å; E380-N382 PolarHBondContact O-N 2.49Å; E380-A383 WeakPolarHBondContact O-CB 3.32Å; E380-A383 PolarHBondContact O-N 3.11Å; E380-E384 PolarHBondContact O-N 2.77Å
381I91Very high84.6Confident79 Ų79110 Ų11041%0.40555%0.548SS..Hα-helixtrans-60.6-42.9177.2-69.1166.3000111L377 V378 A383 E384 I385L377-I381 HydrophobicContact CD1-CD1 4.48Å; L377-I381 HydrophobicContact CG-CD1 4.08Å; L377-I381 VanDerWaalsContact O-CG1 3.31Å; L377-I381 WeakPolarHBondContact O-CG1 3.46Å; L377-I381 PolarHBondContact O-N 3.1Å; V378-I381 PolarHBondContact O-N 2.92Å; I381-A383 VanDerWaalsContact C-N 3.29Å; I381-A383 PolarHBondContact O-N 2.76Å; I381-E384 PolarHBondContact O-N 3.04Å; I381-I385 HydrophobicContact CG2-CD1 3.91Å; I381-I385 WeakPolarHBondContact O-CG1 3.29Å; I381-I385 PolarHBondContact O-N 3.25Å
382N89.1Confident82.5Confident80 Ų80110.6 Ų110.643%0.42855%0.552SS.*Hα-helixtrans-65-34.7178.6-73.3-26.9000112.2V378 E380 L386V378-N382 WeakPolarHBondContact O-CB 3.4Å; V378-N382 VanDerWaalsContact O-CG 3.24Å; V378-N382 PolarHBondContact O-N 3.26Å; V378-N382 PolarHBondContact O-ND2 3.3Å; E380-N382 VanDerWaalsContact C-N 3.32Å; E380-N382 PolarHBondContact O-N 2.49Å; N382-L386 WeakPolarHBondContact O-CG 3.28Å; N382-L386 PolarHBondContact O-N 3.22Å; N382-L386 VanDerWaalsContact O-N 3.14Å
383A88Confident80.2Confident50 Ų50112 Ų11241%0.41356%0.559SS.*Hα-helixtrans-66.6-43.3174.900000111.7D379 E380 I381 I385 L386 E387D379-A383 PolarHBondContact O-N 3.37Å; D379-A383 VanDerWaalsContact O-N 3.08Å; E380-A383 WeakPolarHBondContact O-CB 3.32Å; E380-A383 PolarHBondContact O-N 3.11Å; I381-A383 VanDerWaalsContact C-N 3.29Å; I381-A383 PolarHBondContact O-N 2.76Å; A383-I385 VanDerWaalsContact C-N 3.35Å; A383-I385 PolarHBondContact O-N 2.62Å; A383-L386 PolarHBondContact O-N 3.14Å; A383-E387 PolarHBondContact O-N 2.58Å
384E84.9Confident77.7Confident136 Ų136109.9 Ų109.964%0.63656%0.561SS**Hα-helixtrans-61.3-40.7175.3-73.2-179.2176.100112.4E380 I381 E387 H388E380-E384 PolarHBondContact O-N 2.77Å; I381-E384 PolarHBondContact O-N 3.04Å; E384-E387 PolarHBondContact O-N 3.25Å; E384-H388 PolarHBondContact O-N 2.93Å
385I82.6Confident75.4Confident89 Ų89108.8 Ų108.846%0.45657%0.573SS.*Hα-helixtrans-62.3-43.9176-68167.3000110.9I381 A383 E387 H388 D389I381-I385 HydrophobicContact CG2-CD1 3.91Å; I381-I385 WeakPolarHBondContact O-CG1 3.29Å; I381-I385 PolarHBondContact O-N 3.25Å; A383-I385 VanDerWaalsContact C-N 3.35Å; A383-I385 PolarHBondContact O-N 2.62Å; I385-E387 VanDerWaalsContact C-N 3.34Å; I385-E387 PolarHBondContact O-N 3.15Å; I385-H388 PolarHBondContact O-N 2.91Å; I385-D389 PolarHBondContact O-N 3.5Å
386L79.1Confident72.9Confident125 Ų125108.1 Ų108.165%0.65458%0.583SS**Hα-helixtrans-65.7-35.9178.6-76167000112.6N382 A383 S390N382-L386 WeakPolarHBondContact O-CG 3.28Å; N382-L386 PolarHBondContact O-N 3.22Å; N382-L386 VanDerWaalsContact O-N 3.14Å; A383-L386 PolarHBondContact O-N 3.14Å; L386-S390 WeakPolarHBondContact O-CB 3.46Å; L386-S390 PolarHBondContact O-N 3.33Å
387E75.6Confident70.5Confident139 Ų139106.1 Ų106.165%0.6559%0.591SS**Hα-helixtrans-65.5-42.7173.4-74.7-173.5178.100111.2A383 E384 I385 S390 T391A383-E387 PolarHBondContact O-N 2.58Å; E384-E387 PolarHBondContact O-N 3.25Å; I385-E387 VanDerWaalsContact C-N 3.34Å; I385-E387 PolarHBondContact O-N 3.15Å; E387-S390 PolarHBondContact O-N 3.16Å; E387-S390 PolarHBondContact O-OG 3.37Å; E387-T391 PolarHBondContact O-N 3Å; E387-T391 PolarHBondContact O-OG1 3.18Å
388H67.5Low67.8Low120 Ų120107.3 Ų107.356%0.55661%0.606SS**Hα-helixtrans-64.7-41.7177.9-166.6-69.3000112.9E384 I385 S390 T391 D392E384-H388 PolarHBondContact O-N 2.93Å; I385-H388 PolarHBondContact O-N 2.91Å; H388-S390 PolarHBondContact O-N 3.15Å; H388-T391 PolarHBondContact O-N 3.32Å; H388-T391 PolarHBondContact O-OG1 2.89Å; H388-D392 IonicContact CE1-OD2 2.7Å; H388-D392 IonicContact ND1-OD2 3.83Å
389D62.1Low65.4Low112 Ų112112.1 Ų112.160%0.59963%0.63SS**Hα-helixtrans-67.1-24.6175.8-89.3-6.8000112.6I385I385-D389 PolarHBondContact O-N 3.5Å
390S58.9Low62.8Low79 Ų79114.9 Ų114.955%0.55265%0.645SS**Hα-helixtrans-77.3-22177.2790000113.5L386 E387 H388L386-S390 WeakPolarHBondContact O-CB 3.46Å; L386-S390 PolarHBondContact O-N 3.33Å; E387-S390 PolarHBondContact O-N 3.16Å; E387-S390 PolarHBondContact O-OG 3.37Å; H388-S390 PolarHBondContact O-N 3.15Å
391T56.9Low60.5Low105 Ų105118 Ų11864%0.64466%0.659SS**Hα-helixtrans-86.3-14177.943.10000114.4E387 H388E387-T391 PolarHBondContact O-N 3Å; E387-T391 PolarHBondContact O-OG1 3.18Å; H388-T391 PolarHBondContact O-N 3.32Å; H388-T391 PolarHBondContact O-OG1 2.89Å
392D51.5Low58Low118 Ų118119.1 Ų119.163%0.63167%0.674SS**  trans-98.129.1178.4-85.9-29.3000113.8H388H388-D392 IonicContact CE1-OD2 2.7Å; H388-D392 IonicContact ND1-OD2 3.83Å
393K47.3Very low55.7Low178 Ų178119.1 Ų119.177%0.77469%0.685SS**PPolyproline II helixtrans-77.7122162.9-84.6-174.7178.6176.70109.4A395K393-A395 PolarHBondContact O-N 3.26Å
394P42.4Very low53.6Low119 Ų119125.8 Ų125.877%0.77370%0.704SS**PPolyproline II helixtrans-63.8128.5178.227-31.5000108.9N396P394-N396 PolarHBondContact O-N 3.28Å
395A45.6Very low51.6Low98 Ų98124.7 Ų124.781%0.8170%0.703SS**PPolyproline II helixtrans-55.1123.1169.400000108.4K393 A397K393-A395 PolarHBondContact O-N 3.26Å; A395-A397 PolarHBondContact O-N 3.18Å
396N42.2Very low49.9Very low166 Ų166129.1 Ų129.189%0.88872%0.719SS**  trans-49.3108.6169.6-88.6-23.1000109P394 S398P394-N396 PolarHBondContact O-N 3.28Å; N396-S398 PolarHBondContact O-N 2.87Å
397A43.1Very low48.3Very low87 Ų87129.3 Ų129.372%0.71972%0.717SS**  trans-67.7113.6160.200000107.2A395 D399A395-A397 PolarHBondContact O-N 3.18Å; A397-D399 PolarHBondContact O-N 2.99Å
398S38.1Very low46.9Very low113 Ų113130.6 Ų130.679%0.7972%0.72SS**  trans-63.6105.5156.851.20000107.8N396N396-S398 PolarHBondContact O-N 2.87Å
399D43Very low46Very low158 Ų158129.2 Ų129.285%0.84572%0.72SS**  trans-121.5113.1159.6-90.3-30000109.8A397A397-D399 PolarHBondContact O-N 2.99Å
400D37.6Very low45.6Very low145 Ų145132.9 Ų132.978%0.77573%0.734SS**  trans-74.3112.3168.7-172.110.5000107.8
401H43.5Very low45Very low182 Ų182139.1 Ų139.184%0.84376%0.76SS**  trans-163.1124.2141.5-105.5-7.5000114.2
402S38.8Very low44.4Very low103 Ų103140.9 Ų140.972%0.7277%0.766SS**  trans-67.6150.6169.865.30000113
403A41.1Very low44.1Very low79 Ų79142.1 Ų142.165%0.65377%0.773SS**  122.1118.5124.800000116.6
404K43.5Very low43.9Very low190 Ų190140.1 Ų140.183%0.82677%0.773SS**  trans71.6145.4142.9-67.7179.5178.9178.70116.5
405D43.4Very low44Very low114 Ų114141.3 Ų141.361%0.6177%0.773SS**  cis-176.4145.6-8.7-115.6-33.7000102.7
406K45.8Very low43.9Very low182 Ų182144 Ų14479%0.79177%0.77SS**  trans62.6151.2151.6-62.9173.5-178.4-176.20118.6
407E46Very low44Very low129 Ų129142.5 Ų142.560%0.60376%0.763SS**  cis179.3120.9-18.2168.1165.4-158.900103.6
408K47.3Very low44Very low165 Ų165146.5 Ų146.572%0.71777%0.766SS**  trans64.1157.6145.1-72.7177-170.3154.60119.4
409T47.5Very low44.5Very low91 Ų91149.1 Ų149.156%0.55876%0.764SS**  cis-159.116734.1-8.70000107.2L411T409-L411 VanDerWaalsContact C-CA 3.49Å; T409-L411 CarbonylContact C-O 3.56Å; T409-L411 VanDerWaalsContact CB-N 3.25Å; T409-L411 VanDerWaalsContact CB-O 3.31Å; T409-L411 WeakPolarHBondContact CB-O 3.11Å; T409-L411 CarbonylContact O-C 3Å
410E54.4Low44.6Very low189 Ų189148.3 Ų148.388%0.88376%0.757SS**  cis74.21512.2-94.3-165.5-15200115.9
411L46.3Very low45.2Very low211 Ų211148.6 Ų148.6100%1.10576%0.755SS**  cis-96.5027.9-76.2109.6000120T409T409-L411 VanDerWaalsContact C-CA 3.49Å; T409-L411 CarbonylContact C-O 3.56Å; T409-L411 VanDerWaalsContact CB-N 3.25Å; T409-L411 VanDerWaalsContact CB-O 3.31Å; T409-L411 WeakPolarHBondContact CB-O 3.11Å; T409-L411 CarbonylContact O-C 3Å

Retrieved 411 of 411 residues in 616.4 ms (Link to these results)