A0A077ZBL9_TRITR Loading...

UPF0197 and Serinc domain containing protein

AlphaFold DB , UniProt , Accession A0A077ZBL9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 533 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.4	Very low	38.5	Very low	186 Å²	186	82.6 Å²	82.6	92%	0.916	57%	0.573	S	S	*	*				0	-41.6	0	-62.4	-178.5	83.3	0	0	112	L5	M1-L5 WeakPolarHBondContact O-CD1 3.29Å; M1-L5 PolarHBondContact O-N 2.94Å
2	G	38.4	Very low	38.6	Very low	55 Å²	55	77.6 Å²	77.6	57%	0.567	54%	0.538	S	S	*	.	H	α-helix	trans	-66.5	-35.3	177.5	0	0	0	0	0	117	G6	G2-G6 PolarHBondContact O-N 2.92Å
3	A	35.1	Very low	39	Very low	86 Å²	86	72.8 Å²	72.8	71%	0.711	51%	0.505	S	S	*	.	H	α-helix	trans	-76.7	-28.1	179.6	0	0	0	0	0	113.8
4	A	34.6	Very low	39.3	Very low	64 Å²	64	72.1 Å²	72.1	53%	0.529	51%	0.506	S	S	.	.	H	α-helix	trans	-76.2	-30.4	176.6	0	0	0	0	0	112.1	L8	A4-L8 WeakPolarHBondContact O-CD1 3.43Å; A4-L8 VanDerWaalsContact O-CG 3.25Å; A4-L8 WeakPolarHBondContact O-CG 3.42Å; A4-L8 PolarHBondContact O-N 3.35Å
5	L	42.5	Very low	39.5	Very low	111 Å²	111	68.9 Å²	68.9	58%	0.581	49%	0.485	S	S	*	.	H	α-helix	trans	-76.1	-29.1	174.7	-83.5	152.9	0	0	0	112.9	M1 G9	M1-L5 WeakPolarHBondContact O-CD1 3.29Å; M1-L5 PolarHBondContact O-N 2.94Å; L5-G9 PolarHBondContact O-N 3.19Å
6	G	37.5	Very low	39.8	Very low	49 Å²	49	67.6 Å²	67.6	51%	0.505	47%	0.469	S	S	.	.	H	α-helix	trans	-70.4	-37	176.4	0	0	0	0	0	113.8	G2 G9 A10	G2-G6 PolarHBondContact O-N 2.92Å; G6-G9 PolarHBondContact O-N 2.97Å; G6-A10 PolarHBondContact O-N 3.07Å
7	V	38.4	Very low	40	Very low	116 Å²	116	70.5 Å²	70.5	70%	0.703	48%	0.478	S	S	*	.	H	α-helix	trans	-75.3	-33.4	175.1	178.7	0	0	0	0	111.1	G11	V7-G11 PolarHBondContact O-N 3.22Å
8	L	37.3	Very low	39.9	Very low	111 Å²	111	69.4 Å²	69.4	58%	0.581	47%	0.474	S	S	*	.	H	α-helix	trans	-66.4	-38.8	171	-73.4	167.1	0	0	0	111.6	A4 A10 G11 S12	A4-L8 WeakPolarHBondContact O-CD1 3.43Å; A4-L8 VanDerWaalsContact O-CG 3.25Å; A4-L8 WeakPolarHBondContact O-CG 3.42Å; A4-L8 PolarHBondContact O-N 3.35Å; L8-A10 VanDerWaalsContact C-N 3.34Å; L8-A10 PolarHBondContact O-N 3.2Å; L8-G11 CarbonylContact O-C 3.18Å; L8-G11 WeakPolarHBondContact O-CA 3.37Å; L8-G11 PolarHBondContact O-N 2.95Å; L8-G11 VanDerWaalsContact O-N 3.08Å; L8-S12 PolarHBondContact O-N 3.02Å; L8-S12 PolarHBondContact O-OG 2.74Å
9	G	40	Very low	40.1	Very low	15 Å²	15	66.9 Å²	66.9	16%	0.155	46%	0.457	C	S	.	.	H	α-helix	trans	-61.5	-33.9	178.8	0	0	0	0	0	115	L5 G6 S12 C13	L5-G9 PolarHBondContact O-N 3.19Å; G6-G9 PolarHBondContact O-N 2.97Å; G9-S12 PolarHBondContact O-N 3.48Å; G9-C13 PolarHBondContact O-N 2.8Å; G9-C13 PolarHBondContact O-SG 2.74Å
10	A	39	Very low	40.1	Very low	70 Å²	70	67.9 Å²	67.9	58%	0.579	46%	0.464	S	S	*	.	H	α-helix	trans	-71.1	-36.8	173.2	0	0	0	0	0	111.9	G6 L8 C13 A14	G6-A10 PolarHBondContact O-N 3.07Å; L8-A10 VanDerWaalsContact C-N 3.34Å; L8-A10 PolarHBondContact O-N 3.2Å; A10-C13 PolarHBondContact O-N 2.98Å; A10-A14 PolarHBondContact O-N 2.82Å
11	G	41.3	Very low	40	Very low	46 Å²	46	74.1 Å²	74.1	47%	0.474	48%	0.483	S	S	.	.	H	α-helix	trans	-68.5	-34.5	171.4	0	0	0	0	0	113.4	V7 L8 C13 A15	V7-G11 PolarHBondContact O-N 3.22Å; L8-G11 CarbonylContact O-C 3.18Å; L8-G11 WeakPolarHBondContact O-CA 3.37Å; L8-G11 PolarHBondContact O-N 2.95Å; L8-G11 VanDerWaalsContact O-N 3.08Å; G11-C13 VanDerWaalsContact C-N 3.29Å; G11-C13 PolarHBondContact O-N 3.19Å; G11-A15 PolarHBondContact O-N 3.23Å
12	S	39.6	Very low	40	Very low	22 Å²	22	66.9 Å²	66.9	15%	0.154	46%	0.456	C	S	.	.	H	α-helix	trans	-65.9	-29.6	176	-51.3	0	0	0	0	112.7	L8 G9 Q16 C29	L8-S12 PolarHBondContact O-N 3.02Å; L8-S12 PolarHBondContact O-OG 2.74Å; G9-S12 PolarHBondContact O-N 3.48Å; S12-Q16 WeakPolarHBondContact O-CG 3.23Å; S12-Q16 PolarHBondContact O-N 3.46Å; S12-Q16 VanDerWaalsContact O-N 3.16Å; S12-C29 PolarHBondContact OG-SG 2.78Å
13	C	43.9	Very low	40.3	Very low	16 Å²	16	68.9 Å²	68.9	11%	0.108	46%	0.462	C	S	.	.	H	α-helix	trans	-83.1	-34.2	-178.5	-66	0	0	0	0	112.9	G9 A10 G11 A15 Q16 L17 V45	G9-C13 PolarHBondContact O-N 2.8Å; G9-C13 PolarHBondContact O-SG 2.74Å; A10-C13 PolarHBondContact O-N 2.98Å; G11-C13 VanDerWaalsContact C-N 3.29Å; G11-C13 PolarHBondContact O-N 3.19Å; C13-A15 VanDerWaalsContact C-N 3.28Å; C13-Q16 PolarHBondContact O-N 3.18Å; C13-L17 PolarHBondContact O-N 3.29Å; C13-V45 HydrophobicContact CB-CG1 4.36Å; C13-V45 HydrophobicContact CB-CG2 4.44Å; C13-V45 WeakPolarHBondContact SG-CG2 3.48Å
14	A	43.1	Very low	40.5	Very low	63 Å²	63	68.8 Å²	68.8	52%	0.521	46%	0.46	S	S	.	.	H	α-helix	trans	-64.6	-36.8	168.7	0	0	0	0	0	111	A10 Q16 A18	A10-A14 PolarHBondContact O-N 2.82Å; A14-Q16 VanDerWaalsContact C-N 3.35Å; A14-Q16 PolarHBondContact O-N 2.95Å; A14-A18 WeakPolarHBondContact O-CB 3.43Å; A14-A18 PolarHBondContact O-N 2.96Å
15	A	41.9	Very low	40.6	Very low	24 Å²	24	67.8 Å²	67.8	20%	0.198	45%	0.453	C	S	.	.	H	α-helix	trans	-65.2	-34.1	173.9	0	0	0	0	0	112.7	G11 C13 A18 C19 A25	G11-A15 PolarHBondContact O-N 3.23Å; C13-A15 VanDerWaalsContact C-N 3.28Å; A15-A18 CarbonylContact O-C 3.45Å; A15-A18 PolarHBondContact O-N 2.86Å; A15-C19 WeakPolarHBondContact O-CB 3.4Å; A15-C19 PolarHBondContact O-N 2.89Å; A15-C19 PolarHBondContact O-SG 3.41Å; A15-A25 HydrophobicContact CB-CB 4.36Å
16	Q	45.2	Very low	40.7	Very low	47 Å²	47	64 Å²	64	22%	0.22	44%	0.435	C	S	.	.	H	α-helix	trans	-78.4	-32.1	177.6	-74.3	173.2	-12.5	0	0	113.9	S12 C13 A14 A18 C19 M42	S12-Q16 WeakPolarHBondContact O-CG 3.23Å; S12-Q16 PolarHBondContact O-N 3.46Å; S12-Q16 VanDerWaalsContact O-N 3.16Å; C13-Q16 PolarHBondContact O-N 3.18Å; A14-Q16 VanDerWaalsContact C-N 3.35Å; A14-Q16 PolarHBondContact O-N 2.95Å; Q16-A18 VanDerWaalsContact C-N 3.35Å; Q16-C19 WeakPolarHBondContact O-CB 3.49Å; Q16-C19 PolarHBondContact O-N 3.08Å; Q16-M42 PolarHBondContact OE1-SD 3.28Å
17	L	42	Very low	40.9	Very low	118 Å²	118	65.6 Å²	65.6	62%	0.618	44%	0.438	S	S	*	.	H	α-helix	trans	-68.3	-36.5	166.3	-77.7	166.1	0	0	0	111.2	C13 C19 C20	C13-L17 PolarHBondContact O-N 3.29Å; L17-C19 VanDerWaalsContact C-N 3.35Å; L17-C20 PolarHBondContact O-N 3.48Å
18	A	39.9	Very low	40.8	Very low	51 Å²	51	67.6 Å²	67.6	42%	0.421	44%	0.444	S	S	.	.	H	α-helix	trans	-72.7	-23.4	171.3	0	0	0	0	0	113.3	A14 A15 Q16 C20 F21 G22	A14-A18 WeakPolarHBondContact O-CB 3.43Å; A14-A18 PolarHBondContact O-N 2.96Å; A15-A18 CarbonylContact O-C 3.45Å; A15-A18 PolarHBondContact O-N 2.86Å; Q16-A18 VanDerWaalsContact C-N 3.35Å; A18-C20 PolarHBondContact O-N 3.38Å; A18-F21 CarbonylContact O-C 3.54Å; A18-F21 PolarHBondContact O-N 3.5Å; A18-G22 PolarHBondContact O-N 3.01Å; A18-G22 VanDerWaalsContact O-N 3.13Å
19	C	43.1	Very low	41	Very low	22 Å²	22	65.3 Å²	65.3	15%	0.149	44%	0.437	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.9	-18.3	174.4	-72.3	0	0	0	0	112.7	A15 Q16 L17 F21 C26	A15-C19 WeakPolarHBondContact O-CB 3.4Å; A15-C19 PolarHBondContact O-N 2.89Å; A15-C19 PolarHBondContact O-SG 3.41Å; Q16-C19 WeakPolarHBondContact O-CB 3.49Å; Q16-C19 PolarHBondContact O-N 3.08Å; L17-C19 VanDerWaalsContact C-N 3.35Å; C19-F21 PolarHBondContact O-N 3.09Å; C19-C26 HydrophobicContact CB-CB 4.18Å; C19-C26 WeakPolarHBondContact CB-SG 3.3Å; C19-C26 WeakPolarHBondContact SG-CA 3.48Å; C19-C26 WeakPolarHBondContact SG-CB 3.29Å; C19-C26 PolarHBondContact SG-N 2.98Å; C19-C26 VanDerWaalsContact SG-N 3.42Å; C19-C26 CovalentContact SG-SG 2.04Å; C19-C26 PolarHBondContact SG-SG 3.43Å
20	C	38.9	Very low	41.3	Very low	86 Å²	86	66.6 Å²	66.6	58%	0.581	44%	0.443	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.8	-13.9	170.5	-67	0	0	0	0	112.6	L17 A18	L17-C20 PolarHBondContact O-N 3.48Å; A18-C20 PolarHBondContact O-N 3.38Å
21	F	39.7	Very low	41.4	Very low	198 Å²	198	67.5 Å²	67.5	87%	0.868	45%	0.445	S	S	*	.	T	Hydrogen-bonded Turn	trans	-123.1	-0.1	179.6	-71.2	-82.7	0	0	0	114.3	A18 C19	A18-F21 CarbonylContact O-C 3.54Å; A18-F21 PolarHBondContact O-N 3.5Å; C19-F21 PolarHBondContact O-N 3.09Å
22	G	38	Very low	41.3	Very low	35 Å²	35	68.7 Å²	68.7	36%	0.361	45%	0.451	S	S	.	.			trans	-168.4	130.9	178.7	0	0	0	0	0	115.2	A18 A24	A18-G22 PolarHBondContact O-N 3.01Å; A18-G22 VanDerWaalsContact O-N 3.13Å; G22-A24 PolarHBondContact O-N 3.32Å
23	S	44.8	Very low	41.7	Very low	97 Å²	97	70.3 Å²	70.3	68%	0.678	46%	0.461	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.2	-12.7	-172.5	36.5	0	0	0	0	115.7
24	A	40.6	Very low	42.2	Very low	83 Å²	83	71 Å²	71	69%	0.686	47%	0.465	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.1	-24.4	-171.9	0	0	0	0	0	114.9	G22 S27	G22-A24 PolarHBondContact O-N 3.32Å; A24-S27 PolarHBondContact O-OG 3.33Å
25	A	36.7	Very low	43.1	Very low	44 Å²	44	69.3 Å²	69.3	36%	0.364	45%	0.45	S	S	.	.	S	Bend	trans	-81.6	-20	-176.2	0	0	0	0	0	113.8	A15	A15-A25 HydrophobicContact CB-CB 4.36Å
26	C	44.3	Very low	44.1	Very low	30 Å²	30	68.1 Å²	68.1	20%	0.203	44%	0.44	C	S	.	.	S	Bend	trans	-81.9	-29.2	-176	-102.2	0	0	0	0	114.6	C19	C19-C26 HydrophobicContact CB-CB 4.18Å; C19-C26 WeakPolarHBondContact CB-SG 3.3Å; C19-C26 WeakPolarHBondContact SG-CA 3.48Å; C19-C26 WeakPolarHBondContact SG-CB 3.29Å; C19-C26 PolarHBondContact SG-N 2.98Å; C19-C26 VanDerWaalsContact SG-N 3.42Å; C19-C26 CovalentContact SG-SG 2.04Å; C19-C26 PolarHBondContact SG-SG 3.43Å
27	S	41.6	Very low	45.1	Very low	84 Å²	84	67.1 Å²	67.1	59%	0.587	44%	0.437	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.4	-27.9	-176.7	59.2	0	0	0	0	113	A24	A24-S27 PolarHBondContact O-OG 3.33Å
28	L	36.8	Very low	46.3	Very low	157 Å²	157	63.4 Å²	63.4	82%	0.822	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.9	-22.6	-172.1	-142.3	82.5	0	0	0	113.9
29	C	40.7	Very low	48	Very low	63 Å²	63	61.3 Å²	61.3	43%	0.426	40%	0.402	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.1	-16.8	-173.1	-131.8	0	0	0	0	114	S12	S12-C29 PolarHBondContact OG-SG 2.78Å
30	C	45.9	Very low	49.7	Very low	42 Å²	42	60.3 Å²	60.3	28%	0.284	39%	0.394	S	S	.	.	S	Bend	trans	-107.7	4.4	-173.3	-70.3	0	0	0	0	115	A32	C30-A32 VanDerWaalsContact C-N 3.27Å; C30-A32 PolarHBondContact O-N 2.94Å
31	S	42.4	Very low	51.6	Low	90 Å²	90	58.6 Å²	58.6	63%	0.629	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.3	-13	-176	59.1	0	0	0	0	114.7
32	A	39.2	Very low	53.6	Low	71 Å²	71	50 Å²	50	59%	0.587	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-123.2	2.8	-169	0	0	0	0	0	115.8	C30	C30-A32 VanDerWaalsContact C-N 3.27Å; C30-A32 PolarHBondContact O-N 2.94Å
33	C	47.5	Very low	55.9	Low	56 Å²	56	48.3 Å²	48.3	38%	0.378	33%	0.325	S	S	.	.	S	Bend	trans	-109.6	135.6	-175.8	-73.5	0	0	0	0	112.6
34	P	55	Low	57.9	Low	29 Å²	29	43.7 Å²	43.7	19%	0.188	29%	0.293	C	S	.	.			trans	-60.3	144.7	172.6	-10.1	20.3	0	0	0	111.2	S36 V37 T38	P34-S36 PolarHBondContact O-N 2.91Å; P34-S36 VanDerWaalsContact O-N 3.14Å; P34-V37 HydrophobicContact CB-CG2 4Å; P34-V37 HydrophobicContact CG-CG2 3.63Å; P34-V37 PolarHBondContact O-N 3.41Å; P34-T38 PolarHBondContact O-N 3.38Å; P34-T38 PolarHBondContact O-OG1 3.25Å
35	S	60.7	Low	60	Low	28 Å²	28	40.9 Å²	40.9	20%	0.196	27%	0.267	C	S	.	.	H	α-helix	trans	-51.2	-38.1	178.8	56.7	0	0	0	0	113.2	T39	S35-T39 PolarHBondContact O-N 2.92Å; S35-T39 PolarHBondContact O-OG1 3.38Å
36	S	63.3	Low	62.5	Low	0 Å²	0	38.8 Å²	38.8	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-67.2	-36.2	179	52.6	0	0	0	0	113.8	P34 R40 N389	P34-S36 PolarHBondContact O-N 2.91Å; P34-S36 VanDerWaalsContact O-N 3.14Å; S36-R40 WeakPolarHBondContact O-CG 3.26Å; S36-R40 PolarHBondContact O-N 2.86Å; S36-R40 PolarHBondContact O-NE 2.91Å; S36-N389 PolarHBondContact OG-ND2 3.47Å; S36-N389 PolarHBondContact OG-OD1 3.36Å
37	V	65.3	Low	64.8	Low	26 Å²	26	37.4 Å²	37.4	16%	0.158	24%	0.24	C	C	.	.	H	α-helix	trans	-69.8	-46.7	177.6	-173.7	0	0	0	0	110.3	P34 T39 R40 L41 S353	P34-V37 HydrophobicContact CB-CG2 4Å; P34-V37 HydrophobicContact CG-CG2 3.63Å; P34-V37 PolarHBondContact O-N 3.41Å; V37-T39 VanDerWaalsContact C-N 3.34Å; V37-T39 PolarHBondContact O-N 2.94Å; V37-R40 PolarHBondContact O-N 3.35Å; V37-L41 PolarHBondContact O-N 3.08Å; V37-S353 WeakPolarHBondContact CG2-OG 3.28Å
38	T	67.2	Low	67.2	Low	40 Å²	40	35.3 Å²	35.3	25%	0.245	22%	0.222	C	C	.	.	H	α-helix	trans	-58.5	-46.7	-179.8	-56.6	0	0	0	0	111.1	P34 R40 L41 M42	P34-T38 PolarHBondContact O-N 3.38Å; P34-T38 PolarHBondContact O-OG1 3.25Å; T38-R40 PolarHBondContact O-N 3.38Å; T38-L41 PolarHBondContact O-N 2.9Å; T38-M42 WeakPolarHBondContact O-CG 3.43Å; T38-M42 PolarHBondContact O-N 3.38Å
39	T	76.3	Confident	69.7	Low	7 Å²	7	31.6 Å²	31.6	4%	0.043	20%	0.203	C	C	.	.	H	α-helix	trans	-60	-43.3	178.5	-64.7	0	0	0	0	112.6	S35 V37 M42 Y43 Q122 N123 W142	S35-T39 PolarHBondContact O-N 2.92Å; S35-T39 PolarHBondContact O-OG1 3.38Å; V37-T39 VanDerWaalsContact C-N 3.34Å; V37-T39 PolarHBondContact O-N 2.94Å; T39-M42 PolarHBondContact O-N 3.48Å; T39-Y43 HydrophobicContact CG2-CD2 3.97Å; T39-Y43 HydrophobicContact CG2-CE2 3.6Å; T39-Y43 WeakPolarHBondContact O-CD2 3.19Å; T39-Y43 PolarHBondContact O-N 2.96Å; T39-Y43 VanDerWaalsContact O-N 3.16Å; T39-Q122 HydrophobicContact CG2-CG 4.16Å; T39-N123 PolarHBondContact OG1-OD1 3.14Å; T39-W142 HydrophobicContact CG2-CH2 3.93Å; T39-W142 HydrophobicContact CG2-CZ2 3.83Å
40	R	78.6	Confident	72.2	Confident	0 Å²	0	28.8 Å²	28.8	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-66.5	-39.3	177.5	-70.1	176.6	-70.8	-163.9	-1.3	112.6	S36 V37 T38 M42 Y43 S44 C349 T352 S353 Y396 F401	S36-R40 WeakPolarHBondContact O-CG 3.26Å; S36-R40 PolarHBondContact O-N 2.86Å; S36-R40 PolarHBondContact O-NE 2.91Å; V37-R40 PolarHBondContact O-N 3.35Å; T38-R40 PolarHBondContact O-N 3.38Å; R40-M42 VanDerWaalsContact C-N 3.34Å; R40-Y43 PolarHBondContact O-N 2.7Å; R40-S44 PolarHBondContact O-N 3.48Å; R40-S44 VanDerWaalsContact O-N 3.07Å; R40-S44 PolarHBondContact O-OG 2.91Å; R40-C349 HydrophobicContact CB-CB 4.32Å; R40-T352 PolarHBondContact NH1-O 2.97Å; R40-S353 PolarHBondContact NH2-OG 3.43Å; R40-Y396 HydrophobicContact CG-CE1 4.29Å; R40-Y396 HydrophobicContact CG-CE2 4.39Å; R40-F401 HydrophobicContact CB-CE2 3.96Å; R40-F401 HydrophobicContact CB-CZ 3.77Å; R40-F401 HydrophobicContact CG-CD2 4.24Å; R40-F401 HydrophobicContact CG-CE1 4.22Å; R40-F401 HydrophobicContact CG-CE2 3.67Å; R40-F401 HydrophobicContact CG-CZ 3.67Å
41	L	79.8	Confident	74.4	Confident	51 Å²	51	27.2 Å²	27.2	27%	0.267	17%	0.173	S	C	.	.	H	α-helix	trans	-62.6	-42.1	174.6	-174	66.9	0	0	0	111.1	V37 T38 Y43 S44 V45	V37-L41 PolarHBondContact O-N 3.08Å; T38-L41 PolarHBondContact O-N 2.9Å; L41-Y43 PolarHBondContact O-N 2.97Å; L41-S44 WeakPolarHBondContact O-CB 3.27Å; L41-S44 PolarHBondContact O-N 3.47Å; L41-S44 VanDerWaalsContact O-N 3.12Å; L41-V45 VanDerWaalsContact O-CG2 3.25Å; L41-V45 WeakPolarHBondContact O-CG2 3.34Å; L41-V45 PolarHBondContact O-N 3.44Å
42	M	80.8	Confident	76.8	Confident	17 Å²	17	26.4 Å²	26.4	8%	0.084	16%	0.164	C	C	.	.	H	α-helix	trans	-61.2	-42.9	177.6	-71.4	-54.2	100.3	0	0	112.5	Q16 T38 T39 R40 S44 V45 M46 W142	Q16-M42 PolarHBondContact OE1-SD 3.28Å; T38-M42 WeakPolarHBondContact O-CG 3.43Å; T38-M42 PolarHBondContact O-N 3.38Å; T39-M42 PolarHBondContact O-N 3.48Å; R40-M42 VanDerWaalsContact C-N 3.34Å; M42-S44 VanDerWaalsContact C-N 3.31Å; M42-S44 PolarHBondContact O-N 2.88Å; M42-V45 PolarHBondContact O-N 3.48Å; M42-M46 PolarHBondContact O-N 3.32Å; M42-W142 HydrophobicContact CB-CD2 4.39Å; M42-W142 HydrophobicContact CB-CE3 3.98Å; M42-W142 HydrophobicContact CB-CH2 3.38Å; M42-W142 HydrophobicContact CB-CZ2 3.83Å; M42-W142 HydrophobicContact CB-CZ3 3.46Å; M42-W142 VanDerWaalsContact CB-CZ3 3.46Å; M42-W142 HydrophobicContact CG-CH2 4.19Å; M42-W142 HydrophobicContact CG-CZ2 4.14Å; M42-W142 HydrophobicContact CG-CZ3 4.4Å
43	Y	87	Confident	79.3	Confident	0 Å²	0	25.8 Å²	25.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-63.6	-36.4	174	-74.6	-59.5	0	0	0	112.6	T39 R40 L41 M46 L47 F100 F101 L104 Q122 W142 K145 F401 H402	T39-Y43 HydrophobicContact CG2-CD2 3.97Å; T39-Y43 HydrophobicContact CG2-CE2 3.6Å; T39-Y43 WeakPolarHBondContact O-CD2 3.19Å; T39-Y43 PolarHBondContact O-N 2.96Å; T39-Y43 VanDerWaalsContact O-N 3.16Å; R40-Y43 PolarHBondContact O-N 2.7Å; L41-Y43 PolarHBondContact O-N 2.97Å; Y43-M46 HydrophobicContact CD1-CE 4.01Å; Y43-M46 PolarHBondContact O-N 2.8Å; Y43-L47 PolarHBondContact O-N 3.09Å; Y43-F100 HydrophobicContact CE1-CE1 4.37Å; Y43-F101 HydrophobicContact CD1-CE1 4.08Å; Y43-L104 HydrophobicContact CD1-CD1 4.46Å; Y43-L104 HydrophobicContact CE1-CD1 3.53Å; Y43-Q122 PolarHBondContact OH-OE1 3.43Å; Y43-W142 HydrophobicContact CD1-CH2 4.34Å; Y43-W142 HydrophobicContact CD1-CZ3 4.05Å; Y43-W142 AromaticContact CD2-CH2 3.89Å; Y43-W142 HydrophobicContact CD2-CH2 3.89Å; Y43-W142 HydrophobicContact CD2-CZ3 4.41Å; Y43-W142 HydrophobicContact CE1-CH2 4.16Å; Y43-W142 AromaticContact CE1-CZ3 3.9Å; Y43-W142 HydrophobicContact CE1-CZ3 3.9Å; Y43-W142 AromaticContact CE2-CH2 3.67Å; Y43-W142 HydrophobicContact CE2-CH2 3.67Å; Y43-W142 HydrophobicContact CE2-CZ3 4.26Å; Y43-W142 HydrophobicContact CG-CH2 4.23Å; Y43-W142 HydrophobicContact CG-CZ3 4.31Å; Y43-W142 AromaticContact CZ-CH2 3.83Å; Y43-K145 HydrophobicContact CE1-CD 4.25Å; Y43-K145 WeakPolarHBondContact OH-CE 3.28Å; Y43-K145 PolarHBondContact OH-NZ 3.48Å; Y43-F401 AromaticContact CD2-CE1 3.89Å; Y43-F401 HydrophobicContact CD2-CE1 3.89Å; Y43-F401 HydrophobicContact CG-CE1 4.24Å; Y43-H402 AromaticContact CD2-CE1 3.99Å; Y43-H402 AromaticContact CE1-CE1 3.9Å; Y43-H402 AromaticContact CE2-CE1 3.62Å; Y43-H402 AromaticContact CZ-CE1 3.56Å
44	S	86	Confident	81.4	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-63.8	-45.6	174	-67.3	0	0	0	0	112.3	R40 L41 M42 M46 L47 I48 C349 F405	R40-S44 PolarHBondContact O-N 3.48Å; R40-S44 VanDerWaalsContact O-N 3.07Å; R40-S44 PolarHBondContact O-OG 2.91Å; L41-S44 WeakPolarHBondContact O-CB 3.27Å; L41-S44 PolarHBondContact O-N 3.47Å; L41-S44 VanDerWaalsContact O-N 3.12Å; M42-S44 VanDerWaalsContact C-N 3.31Å; M42-S44 PolarHBondContact O-N 2.88Å; S44-M46 VanDerWaalsContact C-N 3.27Å; S44-M46 PolarHBondContact O-N 3.35Å; S44-L47 PolarHBondContact O-N 2.92Å; S44-I48 WeakPolarHBondContact O-CB 3.33Å; S44-I48 WeakPolarHBondContact O-CD1 3.17Å; S44-I48 WeakPolarHBondContact O-CG1 3.42Å; S44-I48 PolarHBondContact O-N 2.96Å; S44-C349 PolarHBondContact OG-SG 2.86Å; S44-F405 WeakPolarHBondContact OG-CZ 3.47Å
45	V	84.9	Confident	83	Confident	23 Å²	23	24.3 Å²	24.3	14%	0.139	14%	0.143	C	C	.	.	H	α-helix	trans	-59.8	-43.5	177.5	172.7	0	0	0	0	109.9	C13 L41 M42 L47 I48 L49	C13-V45 HydrophobicContact CB-CG1 4.36Å; C13-V45 HydrophobicContact CB-CG2 4.44Å; C13-V45 WeakPolarHBondContact SG-CG2 3.48Å; L41-V45 VanDerWaalsContact O-CG2 3.25Å; L41-V45 WeakPolarHBondContact O-CG2 3.34Å; L41-V45 PolarHBondContact O-N 3.44Å; M42-V45 PolarHBondContact O-N 3.48Å; V45-L47 PolarHBondContact O-N 3.4Å; V45-I48 PolarHBondContact O-N 2.99Å; V45-L49 HydrophobicContact CG1-CD1 3.91Å; V45-L49 HydrophobicContact CG1-CG 4.25Å; V45-L49 WeakPolarHBondContact O-CB 3.27Å; V45-L49 VanDerWaalsContact O-CG 3.23Å; V45-L49 WeakPolarHBondContact O-CG 3.36Å; V45-L49 PolarHBondContact O-N 3.15Å
46	M	89.4	Confident	84.4	Confident	1 Å²	1	27.2 Å²	27.2	1%	0.005	16%	0.156	C	C	.	.	H	α-helix	trans	-62.2	-42.6	176.8	-173.6	-172.1	76.6	0	0	112.6	M42 Y43 S44 L49 G50 F100 F101 Y146 L149	M42-M46 PolarHBondContact O-N 3.32Å; Y43-M46 HydrophobicContact CD1-CE 4.01Å; Y43-M46 PolarHBondContact O-N 2.8Å; S44-M46 VanDerWaalsContact C-N 3.27Å; S44-M46 PolarHBondContact O-N 3.35Å; M46-L49 PolarHBondContact O-N 2.86Å; M46-G50 PolarHBondContact O-N 3.49Å; M46-F100 HydrophobicContact CE-CD1 3.46Å; M46-F100 VanDerWaalsContact CE-CD1 3.46Å; M46-F100 HydrophobicContact CE-CE1 3.1Å; M46-F100 HydrophobicContact CE-CZ 3.95Å; M46-F100 HydrophobicContact SD-CD1 4.32Å; M46-F100 HydrophobicContact SD-CE1 3.68Å; M46-F100 HydrophobicContact SD-CZ 3.9Å; M46-F101 HydrophobicContact CE-CD1 4.43Å; M46-F101 HydrophobicContact CE-CE1 3.5Å; M46-F101 VanDerWaalsContact CE-CE1 3.5Å; M46-F101 HydrophobicContact CE-CE2 3.9Å; M46-F101 HydrophobicContact CE-CZ 3.17Å; M46-Y146 HydrophobicContact CB-CE1 3.91Å; M46-Y146 HydrophobicContact CG-CD1 4.17Å; M46-Y146 HydrophobicContact CG-CE1 3.76Å; M46-L149 HydrophobicContact CE-CD2 4.44Å; M46-L149 HydrophobicContact CG-CD2 3.55Å; M46-L149 HydrophobicContact SD-CD2 3.95Å
47	L	92	Very high	85.4	Confident	0 Å²	0	28.7 Å²	28.7	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-64.5	-42	174.6	-179.9	64.1	0	0	0	112.1	Y43 S44 V45 G50 T51 M97 F101 W341 V345 F405 A408	Y43-L47 PolarHBondContact O-N 3.09Å; S44-L47 PolarHBondContact O-N 2.92Å; V45-L47 PolarHBondContact O-N 3.4Å; L47-G50 PolarHBondContact O-N 3.39Å; L47-T51 WeakPolarHBondContact O-CB 3.28Å; L47-T51 PolarHBondContact O-N 2.94Å; L47-T51 PolarHBondContact O-OG1 3.45Å; L47-M97 HydrophobicContact CD1-SD 4.42Å; L47-F101 HydrophobicContact CB-CE2 4.15Å; L47-F101 HydrophobicContact CB-CZ 4.01Å; L47-F101 HydrophobicContact CD1-CE2 3.8Å; L47-F101 HydrophobicContact CD1-CZ 4.47Å; L47-F101 HydrophobicContact CG-CE2 4.47Å; L47-W341 HydrophobicContact CD1-CZ2 4.21Å; L47-W341 HydrophobicContact CD2-CH2 4.19Å; L47-W341 HydrophobicContact CD2-CZ2 3.57Å; L47-W341 HydrophobicContact CG-CH2 3.91Å; L47-W341 HydrophobicContact CG-CZ2 3.64Å; L47-V345 HydrophobicContact CD2-CG1 4.24Å; L47-V345 HydrophobicContact CD2-CG2 4.34Å; L47-F405 HydrophobicContact CB-CD1 4.23Å; L47-F405 HydrophobicContact CB-CE1 4.37Å; L47-F405 HydrophobicContact CD2-CD1 3.72Å; L47-F405 HydrophobicContact CD2-CE1 4.04Å; L47-F405 HydrophobicContact CD2-CG 4.33Å; L47-A408 HydrophobicContact CD2-CB 3.9Å
48	I	91.7	Very high	86.3	Confident	41 Å²	41	28.1 Å²	28.1	21%	0.21	16%	0.159	C	C	.	.	H	α-helix	trans	-64.7	-45.4	177.3	-68.4	164.3	0	0	0	110.3	S44 V45 G50 T51 V52 W341 L342 L346	S44-I48 WeakPolarHBondContact O-CB 3.33Å; S44-I48 WeakPolarHBondContact O-CD1 3.17Å; S44-I48 WeakPolarHBondContact O-CG1 3.42Å; S44-I48 PolarHBondContact O-N 2.96Å; V45-I48 PolarHBondContact O-N 2.99Å; I48-G50 PolarHBondContact O-N 2.89Å; I48-T51 WeakPolarHBondContact O-CB 3.33Å; I48-T51 PolarHBondContact O-N 3.41Å; I48-V52 HydrophobicContact CG2-CG2 4.43Å; I48-V52 WeakPolarHBondContact O-CG2 3.47Å; I48-V52 PolarHBondContact O-N 2.93Å; I48-W341 HydrophobicContact CG1-CH2 4.46Å; I48-L342 HydrophobicContact CD1-CD1 3.53Å; I48-L342 HydrophobicContact CG1-CD1 3.65Å; I48-L342 HydrophobicContact CG2-CD1 4.45Å; I48-L346 HydrophobicContact CD1-CD2 4.14Å
49	L	91.1	Very high	87.1	Confident	79 Å²	79	28.9 Å²	28.9	41%	0.414	16%	0.164	S	C	.	.	H	α-helix	trans	-60.7	-45.4	177	-73.4	173.8	0	0	0	111.3	V45 M46 T51 V52 V53 Y146	V45-L49 HydrophobicContact CG1-CD1 3.91Å; V45-L49 HydrophobicContact CG1-CG 4.25Å; V45-L49 WeakPolarHBondContact O-CB 3.27Å; V45-L49 VanDerWaalsContact O-CG 3.23Å; V45-L49 WeakPolarHBondContact O-CG 3.36Å; V45-L49 PolarHBondContact O-N 3.15Å; M46-L49 PolarHBondContact O-N 2.86Å; L49-T51 VanDerWaalsContact C-N 3.28Å; L49-T51 PolarHBondContact O-N 3.03Å; L49-V52 PolarHBondContact O-N 3.02Å; L49-V53 WeakPolarHBondContact O-CG2 3.39Å; L49-V53 PolarHBondContact O-N 3.11Å; L49-Y146 HydrophobicContact CD1-CE1 4.24Å
50	G	92.4	Very high	87.2	Confident	4 Å²	4	32 Å²	32	4%	0.041	18%	0.184	C	C	.	.	H	α-helix	trans	-64.3	-33.4	175.9	0	0	0	0	0	113.3	M46 L47 I48 S54 M97	M46-G50 PolarHBondContact O-N 3.49Å; L47-G50 PolarHBondContact O-N 3.39Å; I48-G50 PolarHBondContact O-N 2.89Å; G50-S54 PolarHBondContact O-N 2.99Å; G50-S54 PolarHBondContact O-OG 3.12Å; G50-M97 WeakPolarHBondContact CA-SD 3.44Å
51	T	92.5	Very high	87.2	Confident	9 Å²	9	35.9 Å²	35.9	6%	0.055	21%	0.212	C	C	.	.	H	α-helix	trans	-67.5	-44.4	172.6	-59.6	0	0	0	0	111.7	L47 I48 L49 V53 S54 C55 M338 W341 V412	L47-T51 WeakPolarHBondContact O-CB 3.28Å; L47-T51 PolarHBondContact O-N 2.94Å; L47-T51 PolarHBondContact O-OG1 3.45Å; I48-T51 WeakPolarHBondContact O-CB 3.33Å; I48-T51 PolarHBondContact O-N 3.41Å; L49-T51 VanDerWaalsContact C-N 3.28Å; L49-T51 PolarHBondContact O-N 3.03Å; T51-V53 VanDerWaalsContact C-N 3.33Å; T51-V53 PolarHBondContact O-N 3.44Å; T51-S54 CarbonylContact O-C 3.56Å; T51-S54 WeakPolarHBondContact O-CA 3.26Å; T51-S54 WeakPolarHBondContact O-CB 3.29Å; T51-S54 PolarHBondContact O-N 3.42Å; T51-S54 VanDerWaalsContact O-N 3.1Å; T51-C55 PolarHBondContact O-N 3.22Å; T51-C55 PolarHBondContact O-SG 3Å; T51-C55 VanDerWaalsContact O-SG 3.33Å; T51-M338 HydrophobicContact CG2-CE 3.36Å; T51-W341 HydrophobicContact CG2-CH2 4.21Å; T51-W341 HydrophobicContact CG2-CZ3 4.1Å; T51-W341 VanDerWaalsContact OG1-CH2 3.3Å; T51-W341 WeakPolarHBondContact OG1-CH2 3.31Å; T51-V412 HydrophobicContact CG2-CG1 3.74Å; T51-V412 HydrophobicContact CG2-CG2 4.33Å
52	V	91.9	Very high	87.3	Confident	72 Å²	72	37 Å²	37	44%	0.436	22%	0.217	S	C	.	.	H	α-helix	trans	-59.9	-44.6	175.4	170.2	0	0	0	0	110.6	I48 L49 S54 C55 L56	I48-V52 HydrophobicContact CG2-CG2 4.43Å; I48-V52 WeakPolarHBondContact O-CG2 3.47Å; I48-V52 PolarHBondContact O-N 2.93Å; L49-V52 PolarHBondContact O-N 3.02Å; V52-S54 VanDerWaalsContact C-N 3.28Å; V52-S54 PolarHBondContact O-N 3.31Å; V52-C55 WeakPolarHBondContact O-CB 3.42Å; V52-C55 PolarHBondContact O-N 2.96Å; V52-C55 VanDerWaalsContact O-N 3.15Å; V52-L56 HydrophobicContact CG1-CD1 4.33Å; V52-L56 HydrophobicContact CG1-CG 4.48Å; V52-L56 WeakPolarHBondContact O-CG 3.2Å; V52-L56 PolarHBondContact O-N 3.49Å
53	V	91.9	Very high	87.2	Confident	59 Å²	59	36.2 Å²	36.2	36%	0.358	21%	0.213	S	C	.	.	H	α-helix	trans	-59.6	-40.8	174.6	171.3	0	0	0	0	111.3	L49 T51 L56 M57 M93	L49-V53 WeakPolarHBondContact O-CG2 3.39Å; L49-V53 PolarHBondContact O-N 3.11Å; T51-V53 VanDerWaalsContact C-N 3.33Å; T51-V53 PolarHBondContact O-N 3.44Å; V53-L56 PolarHBondContact O-N 3.43Å; V53-M57 HydrophobicContact CG1-CE 3.79Å; V53-M57 WeakPolarHBondContact O-CG 3.29Å; V53-M57 PolarHBondContact O-N 2.85Å; V53-M57 VanDerWaalsContact O-N 3.1Å; V53-M93 HydrophobicContact CB-CE 4.07Å; V53-M93 HydrophobicContact CG1-CE 3.94Å; V53-M93 HydrophobicContact CG1-CG 4.39Å; V53-M93 HydrophobicContact CG1-SD 4.15Å
54	S	91.5	Very high	86.7	Confident	0 Å²	0	40.7 Å²	40.7	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-63.2	-40.8	175.2	-55	0	0	0	0	111.9	G50 T51 V52 M57 M93	G50-S54 PolarHBondContact O-N 2.99Å; G50-S54 PolarHBondContact O-OG 3.12Å; T51-S54 CarbonylContact O-C 3.56Å; T51-S54 WeakPolarHBondContact O-CA 3.26Å; T51-S54 WeakPolarHBondContact O-CB 3.29Å; T51-S54 PolarHBondContact O-N 3.42Å; T51-S54 VanDerWaalsContact O-N 3.1Å; V52-S54 VanDerWaalsContact C-N 3.28Å; V52-S54 PolarHBondContact O-N 3.31Å; S54-M57 PolarHBondContact O-N 3.37Å; S54-M93 VanDerWaalsContact OG-CG 3.24Å; S54-M93 WeakPolarHBondContact OG-CG 3.47Å
55	C	89.3	Confident	86.4	Confident	53 Å²	53	49.3 Å²	49.3	36%	0.358	27%	0.267	S	S	.	.	H	α-helix	trans	-64.5	-38.1	173.2	-64.7	0	0	0	0	112.4	T51 V52 M57 L58	T51-C55 PolarHBondContact O-N 3.22Å; T51-C55 PolarHBondContact O-SG 3Å; T51-C55 VanDerWaalsContact O-SG 3.33Å; V52-C55 WeakPolarHBondContact O-CB 3.42Å; V52-C55 PolarHBondContact O-N 2.96Å; V52-C55 VanDerWaalsContact O-N 3.15Å; C55-M57 VanDerWaalsContact C-N 3.29Å; C55-M57 PolarHBondContact O-N 3.47Å; C55-L58 WeakPolarHBondContact O-CB 3.34Å; C55-L58 PolarHBondContact O-N 2.9Å; C55-L58 VanDerWaalsContact O-N 3.14Å
56	L	88.8	Confident	86	Confident	90 Å²	90	49.5 Å²	49.5	47%	0.471	27%	0.267	S	S	.	.	H	α-helix	trans	-63.3	-36.2	176.5	-69.4	173.9	0	0	0	111.4	V52 V53 L58 V59 I62	V52-L56 HydrophobicContact CG1-CD1 4.33Å; V52-L56 HydrophobicContact CG1-CG 4.48Å; V52-L56 WeakPolarHBondContact O-CG 3.2Å; V52-L56 PolarHBondContact O-N 3.49Å; V53-L56 PolarHBondContact O-N 3.43Å; L56-L58 PolarHBondContact O-N 3.43Å; L56-V59 VanDerWaalsContact O-CB 3.31Å; L56-V59 WeakPolarHBondContact O-CB 3.25Å; L56-V59 WeakPolarHBondContact O-CG2 3.38Å; L56-V59 PolarHBondContact O-N 3.45Å; L56-I62 HydrophobicContact CB-CD1 4.13Å; L56-I62 WeakPolarHBondContact O-CD1 3.35Å
57	M	85.7	Confident	85.2	Confident	30 Å²	30	50.2 Å²	50.2	15%	0.148	27%	0.273	C	S	.	.	H	α-helix	trans	-64	-19.9	176	-68.6	171.1	176.7	0	0	113.6	V53 S54 C55 Q63 M93 F157	V53-M57 HydrophobicContact CG1-CE 3.79Å; V53-M57 WeakPolarHBondContact O-CG 3.29Å; V53-M57 PolarHBondContact O-N 2.85Å; V53-M57 VanDerWaalsContact O-N 3.1Å; S54-M57 PolarHBondContact O-N 3.37Å; C55-M57 VanDerWaalsContact C-N 3.29Å; C55-M57 PolarHBondContact O-N 3.47Å; M57-Q63 WeakPolarHBondContact O-CG 3.27Å; M57-M93 HydrophobicContact CE-CB 4.33Å; M57-M93 HydrophobicContact CE-CG 4.45Å; M57-M93 HydrophobicContact SD-CB 3.94Å; M57-M93 HydrophobicContact SD-CG 4.38Å; M57-F157 HydrophobicContact CE-CE1 4.45Å; M57-F157 HydrophobicContact CE-CE2 3.78Å; M57-F157 HydrophobicContact CE-CZ 3.37Å; M57-F157 HydrophobicContact SD-CZ 3.82Å
58	L	84	Confident	84.3	Confident	14 Å²	14	55.3 Å²	55.3	7%	0.073	30%	0.297	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.9	-9.4	174.8	-73.5	150.4	0	0	0	113	C55 L56 Q63 Y87 V90 V330 L416	C55-L58 WeakPolarHBondContact O-CB 3.34Å; C55-L58 PolarHBondContact O-N 2.9Å; C55-L58 VanDerWaalsContact O-N 3.14Å; L56-L58 PolarHBondContact O-N 3.43Å; L58-Q63 VanDerWaalsContact C-NE2 3.35Å; L58-Q63 PolarHBondContact O-NE2 3.4Å; L58-Y87 HydrophobicContact CD2-CD1 3.78Å; L58-Y87 HydrophobicContact CD2-CE1 3.92Å; L58-V90 HydrophobicContact CD1-CG2 3.73Å; L58-V90 HydrophobicContact CD2-CG2 4.24Å; L58-V90 HydrophobicContact CG-CG2 3.75Å; L58-V330 HydrophobicContact CD1-CG2 3.6Å; L58-V330 HydrophobicContact CD2-CG2 4.48Å; L58-V330 HydrophobicContact CG-CG2 4.45Å; L58-L416 HydrophobicContact CD1-CB 4Å; L58-L416 HydrophobicContact CD1-CD1 4.46Å; L58-L416 HydrophobicContact CD1-CD2 4.22Å; L58-L416 HydrophobicContact CD1-CG 4.46Å
59	V	84.1	Confident	83.4	Confident	57 Å²	57	54.5 Å²	54.5	35%	0.345	29%	0.294	S	S	.	.	S	Bend	trans	-68.3	129.2	177.3	177.6	0	0	0	0	109.6	L56 S61 I62 Q63	L56-V59 VanDerWaalsContact O-CB 3.31Å; L56-V59 WeakPolarHBondContact O-CB 3.25Å; L56-V59 WeakPolarHBondContact O-CG2 3.38Å; L56-V59 PolarHBondContact O-N 3.45Å; V59-S61 PolarHBondContact O-N 2.71Å; V59-S61 VanDerWaalsContact O-N 3.09Å; V59-I62 HydrophobicContact CB-CD1 4.48Å; V59-I62 PolarHBondContact O-N 3Å; V59-Q63 PolarHBondContact O-N 2.92Å
60	P	78	Confident	82.2	Confident	71 Å²	71	56.8 Å²	56.8	46%	0.461	31%	0.307	S	S	.	.	H	α-helix	trans	-57.4	-32.3	-173.9	20.8	-33.8	0	0	0	113.4	I62 Q63 Q64 Y327	P60-I62 VanDerWaalsContact C-N 3.34Å; P60-I62 PolarHBondContact O-N 3.49Å; P60-Q63 PolarHBondContact O-N 3.3Å; P60-Q64 PolarHBondContact O-N 3.22Å; P60-Y327 HydrophobicContact CB-CD2 4.05Å; P60-Y327 HydrophobicContact CB-CG 4.35Å
61	S	79.4	Confident	81.1	Confident	83 Å²	83	63.5 Å²	63.5	58%	0.58	33%	0.331	S	S	*	.	H	α-helix	trans	-63.5	-36	175.7	-49.7	0	0	0	0	113.4	V59 R65	V59-S61 PolarHBondContact O-N 2.71Å; V59-S61 VanDerWaalsContact O-N 3.09Å; S61-R65 VanDerWaalsContact O-CG 3.31Å; S61-R65 WeakPolarHBondContact O-CG 3.25Å
62	I	81.4	Confident	79.8	Confident	73 Å²	73	63.9 Å²	63.9	37%	0.374	33%	0.332	S	S	.	.	H	α-helix	trans	-79.4	-39.4	177.8	-68.9	169.6	0	0	0	109.6	L56 V59 P60 Q64 R65 L66	L56-I62 HydrophobicContact CB-CD1 4.13Å; L56-I62 WeakPolarHBondContact O-CD1 3.35Å; V59-I62 HydrophobicContact CB-CD1 4.48Å; V59-I62 PolarHBondContact O-N 3Å; P60-I62 VanDerWaalsContact C-N 3.34Å; P60-I62 PolarHBondContact O-N 3.49Å; I62-Q64 VanDerWaalsContact C-N 3.34Å; I62-Q64 PolarHBondContact O-N 3.27Å; I62-R65 PolarHBondContact O-N 3.01Å; I62-L66 WeakPolarHBondContact O-CB 3.5Å; I62-L66 PolarHBondContact O-N 2.91Å
63	Q	78	Confident	78.6	Confident	1 Å²	1	61 Å²	61	1%	0.005	32%	0.315	C	S	.	.	H	α-helix	trans	-57.1	-45.9	175.6	-65.7	-169.3	26.6	0	0	111.7	M57 L58 V59 P60 R65 L66 A67 Y327 A328	M57-Q63 WeakPolarHBondContact O-CG 3.27Å; L58-Q63 VanDerWaalsContact C-NE2 3.35Å; L58-Q63 PolarHBondContact O-NE2 3.4Å; V59-Q63 PolarHBondContact O-N 2.92Å; P60-Q63 PolarHBondContact O-N 3.3Å; Q63-R65 PolarHBondContact O-N 2.96Å; Q63-L66 PolarHBondContact O-N 3.2Å; Q63-A67 WeakPolarHBondContact O-CB 3.26Å; Q63-A67 PolarHBondContact O-N 3.21Å; Q63-Y327 HydrophobicContact CB-CD1 3.98Å; Q63-Y327 HydrophobicContact CB-CE1 4.24Å; Q63-Y327 VanDerWaalsContact OE1-CD1 3.28Å; Q63-A328 PolarHBondContact NE2-O 2.91Å
64	Q	76.8	Confident	77.1	Confident	94 Å²	94	66.1 Å²	66.1	44%	0.439	33%	0.333	S	S	.	.	H	α-helix	trans	-60.2	-45.3	177.2	-174.6	-178.7	-10.2	0	0	112	P60 I62 L66 A67 E68	P60-Q64 PolarHBondContact O-N 3.22Å; I62-Q64 VanDerWaalsContact C-N 3.34Å; I62-Q64 PolarHBondContact O-N 3.27Å; Q64-L66 VanDerWaalsContact C-N 3.27Å; Q64-L66 PolarHBondContact O-N 3.17Å; Q64-A67 PolarHBondContact O-N 2.89Å; Q64-E68 PolarHBondContact NE2-OE1 3.18Å; Q64-E68 WeakPolarHBondContact O-CG 3.33Å; Q64-E68 PolarHBondContact O-N 2.92Å
65	R	79.5	Confident	75.3	Confident	181 Å²	181	75.1 Å²	75.1	68%	0.683	37%	0.372	S	S	*	.	H	α-helix	trans	-63.1	-35.5	178	-68.5	-64.6	-170.5	-171.6	3.1	112.7	S61 I62 Q63 E68	S61-R65 VanDerWaalsContact O-CG 3.31Å; S61-R65 WeakPolarHBondContact O-CG 3.25Å; I62-R65 PolarHBondContact O-N 3.01Å; Q63-R65 PolarHBondContact O-N 2.96Å; R65-E68 IonicContact NH1-OE2 3.71Å
66	L	76.3	Confident	73.5	Confident	28 Å²	28	79.6 Å²	79.6	15%	0.147	39%	0.391	C	S	.	.	H	α-helix	trans	-77.2	-37.7	180	-166.1	68.4	0	0	0	111.8	I62 Q63 Q64 E68 S69 W71 F72 S89	I62-L66 WeakPolarHBondContact O-CB 3.5Å; I62-L66 PolarHBondContact O-N 2.91Å; Q63-L66 PolarHBondContact O-N 3.2Å; Q64-L66 VanDerWaalsContact C-N 3.27Å; Q64-L66 PolarHBondContact O-N 3.17Å; L66-E68 VanDerWaalsContact C-N 3.34Å; L66-S69 WeakPolarHBondContact O-CB 3.2Å; L66-S69 PolarHBondContact O-N 3.23Å; L66-S69 VanDerWaalsContact O-N 3.1Å; L66-S69 PolarHBondContact O-OG 3.26Å; L66-W71 HydrophobicContact CD1-CZ2 4.37Å; L66-F72 HydrophobicContact CD1-CB 4.07Å; L66-F72 HydrophobicContact CD1-CD1 4.31Å; L66-F72 HydrophobicContact CD1-CD2 3.96Å; L66-F72 HydrophobicContact CD1-CE2 4.47Å; L66-F72 HydrophobicContact CD1-CG 3.85Å; L66-F72 HydrophobicContact CD2-CD1 3.79Å; L66-F72 HydrophobicContact CD2-CD2 4.03Å; L66-F72 HydrophobicContact CD2-CE1 3.52Å; L66-F72 HydrophobicContact CD2-CE2 3.79Å; L66-F72 HydrophobicContact CD2-CG 4.02Å; L66-F72 HydrophobicContact CD2-CZ 3.51Å; L66-F72 HydrophobicContact CG-CB 4.18Å; L66-F72 HydrophobicContact CG-CD1 3.59Å; L66-F72 HydrophobicContact CG-CD2 4.05Å; L66-F72 HydrophobicContact CG-CE1 3.88Å; L66-F72 HydrophobicContact CG-CE2 4.32Å; L66-F72 HydrophobicContact CG-CG 3.67Å; L66-F72 HydrophobicContact CG-CZ 4.23Å; L66-S89 WeakPolarHBondContact CD2-OG 3.22Å
67	A	72.1	Confident	71.8	Confident	16 Å²	16	81.5 Å²	81.5	13%	0.132	40%	0.401	C	S	.	.	H	α-helix	trans	-61.9	-39.7	173	0	0	0	0	0	112.1	Q63 Q64 S69 T85	Q63-A67 WeakPolarHBondContact O-CB 3.26Å; Q63-A67 PolarHBondContact O-N 3.21Å; Q64-A67 PolarHBondContact O-N 2.89Å; A67-S69 PolarHBondContact O-N 3.11Å; A67-T85 HydrophobicContact CB-CG2 3.79Å
68	E	74.2	Confident	70.1	Confident	107 Å²	107	86.5 Å²	86.5	50%	0.5	43%	0.429	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.5	-18.6	174.5	-74.7	170.6	-170.7	0	0	113	Q64 R65 L66 N70	Q64-E68 PolarHBondContact NE2-OE1 3.18Å; Q64-E68 WeakPolarHBondContact O-CG 3.33Å; Q64-E68 PolarHBondContact O-N 2.92Å; R65-E68 IonicContact NH1-OE2 3.71Å; L66-E68 VanDerWaalsContact C-N 3.34Å; E68-N70 PolarHBondContact O-N 3.24Å
69	S	72	Confident	68.7	Low	23 Å²	23	95 Å²	95	16%	0.161	47%	0.465	C	S	.	.			trans	-84.3	115.5	-175.8	81.6	0	0	0	0	112.2	L66 A67 W71 F72 C73	L66-S69 WeakPolarHBondContact O-CB 3.2Å; L66-S69 PolarHBondContact O-N 3.23Å; L66-S69 VanDerWaalsContact O-N 3.1Å; L66-S69 PolarHBondContact O-OG 3.26Å; A67-S69 PolarHBondContact O-N 3.11Å; S69-W71 PolarHBondContact O-N 3.41Å; S69-W71 VanDerWaalsContact O-N 3.08Å; S69-W71 PolarHBondContact OG-NE1 3.18Å; S69-F72 PolarHBondContact O-N 2.98Å; S69-F72 WeakPolarHBondContact OG-CB 3.29Å; S69-C73 PolarHBondContact O-N 3.24Å; S69-C73 VanDerWaalsContact O-N 3.16Å
70	N	65.8	Low	67.5	Low	128 Å²	128	97.3 Å²	97.3	68%	0.684	47%	0.472	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	-22.3	-176.1	-69	-29.5	0	0	0	114.8	E68	E68-N70 PolarHBondContact O-N 3.24Å
71	W	70.7	Confident	66.9	Low	145 Å²	145	95.3 Å²	95.3	55%	0.549	46%	0.46	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.4	-28.3	-178.5	73.8	-79.2	0	0	0	112.7	L66 S69 F157	L66-W71 HydrophobicContact CD1-CZ2 4.37Å; S69-W71 PolarHBondContact O-N 3.41Å; S69-W71 VanDerWaalsContact O-N 3.08Å; S69-W71 PolarHBondContact OG-NE1 3.18Å; W71-F157 HydrophobicContact CH2-CB 3.86Å; W71-F157 HydrophobicContact CH2-CD1 4.16Å; W71-F157 HydrophobicContact CH2-CG 4.26Å; W71-F157 HydrophobicContact CZ3-CB 3.91Å
72	F	65.4	Low	66	Low	17 Å²	17	95.7 Å²	95.7	8%	0.075	46%	0.455	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.3	-46.1	178.7	-170.2	-96.7	0	0	0	111	L66 S69 T85 Q88 S89 R92 F157	L66-F72 HydrophobicContact CD1-CB 4.07Å; L66-F72 HydrophobicContact CD1-CD1 4.31Å; L66-F72 HydrophobicContact CD1-CD2 3.96Å; L66-F72 HydrophobicContact CD1-CE2 4.47Å; L66-F72 HydrophobicContact CD1-CG 3.85Å; L66-F72 HydrophobicContact CD2-CD1 3.79Å; L66-F72 HydrophobicContact CD2-CD2 4.03Å; L66-F72 HydrophobicContact CD2-CE1 3.52Å; L66-F72 HydrophobicContact CD2-CE2 3.79Å; L66-F72 HydrophobicContact CD2-CG 4.02Å; L66-F72 HydrophobicContact CD2-CZ 3.51Å; L66-F72 HydrophobicContact CG-CB 4.18Å; L66-F72 HydrophobicContact CG-CD1 3.59Å; L66-F72 HydrophobicContact CG-CD2 4.05Å; L66-F72 HydrophobicContact CG-CE1 3.88Å; L66-F72 HydrophobicContact CG-CE2 4.32Å; L66-F72 HydrophobicContact CG-CG 3.67Å; L66-F72 HydrophobicContact CG-CZ 4.23Å; S69-F72 PolarHBondContact O-N 2.98Å; S69-F72 WeakPolarHBondContact OG-CB 3.29Å; F72-T85 HydrophobicContact CD1-CG2 4.48Å; F72-T85 HydrophobicContact CE1-CG2 4.24Å; F72-Q88 HydrophobicContact CZ-CB 4.43Å; F72-S89 VanDerWaalsContact CZ-OG 3.24Å; F72-S89 WeakPolarHBondContact CZ-OG 3.49Å; F72-R92 VanDerWaalsContact CE2-NH1 3.32Å; F72-F157 HydrophobicContact CD2-CD1 4.03Å; F72-F157 HydrophobicContact CD2-CE1 4.42Å; F72-F157 AromaticContact CE2-CD1 3.67Å; F72-F157 HydrophobicContact CE2-CD1 3.67Å; F72-F157 AromaticContact CE2-CE1 3.74Å; F72-F157 HydrophobicContact CE2-CE1 3.74Å
73	C	65.7	Low	65.1	Low	11 Å²	11	96.5 Å²	96.5	7%	0.074	45%	0.454	C	S	.	.	S	Bend	trans	-108.6	91.3	178.9	-167.4	0	0	0	0	110.4	S69 K75 C81	S69-C73 PolarHBondContact O-N 3.24Å; S69-C73 VanDerWaalsContact O-N 3.16Å; C73-K75 PolarHBondContact O-N 3.03Å; C73-C81 VanDerWaalsContact CA-SG 3.52Å; C73-C81 HydrophobicContact CB-CB 4.4Å; C73-C81 WeakPolarHBondContact CB-SG 3.31Å; C73-C81 WeakPolarHBondContact SG-CB 3.4Å; C73-C81 CovalentContact SG-SG 2.02Å; C73-C81 PolarHBondContact SG-SG 3.43Å
74	K	60.1	Low	64.5	Low	167 Å²	167	97.1 Å²	97.1	73%	0.726	46%	0.459	S	S	*	.			trans	-72.4	114.4	171.7	-154.4	173.9	-172.6	178.9	0	107.1	L76	K74-L76 PolarHBondContact O-N 3.03Å
75	K	54.7	Low	64.5	Low	188 Å²	188	92.7 Å²	92.7	82%	0.817	44%	0.438	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.4	12.6	179.2	-77.6	-173.2	175.1	-177.4	0	116	C73 L77	C73-K75 PolarHBondContact O-N 3.03Å; K75-L77 VanDerWaalsContact C-N 3.32Å; K75-L77 PolarHBondContact O-N 3.39Å
76	L	51.7	Low	64.5	Low	147 Å²	147	84 Å²	84	77%	0.77	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81	-7.8	-176.6	-140.2	82.5	0	0	0	113.7	K74	K74-L76 PolarHBondContact O-N 3.03Å
77	L	51.9	Low	64.8	Low	131 Å²	131	83.1 Å²	83.1	69%	0.686	40%	0.4	S	S	*	.	S	Bend	trans	-123.4	117.2	172.3	-76	160.4	0	0	0	109.5	K75	K75-L77 VanDerWaalsContact C-N 3.32Å; K75-L77 PolarHBondContact O-N 3.39Å
78	N	49.7	Very low	65.2	Low	134 Å²	134	83.8 Å²	83.8	72%	0.717	40%	0.401	S	S	*	.			trans	-51	135.7	-179.2	-90.7	-41.3	0	0	0	112.8	E80	N78-E80 PolarHBondContact O-N 3.01Å
79	F	54.7	Low	65.7	Low	193 Å²	193	78.7 Å²	78.7	85%	0.846	38%	0.377	S	S	*	.	S	Bend	trans	62.6	-14.2	157.9	-74.8	-81.4	0	0	0	122.5
80	E	59.6	Low	66.5	Low	106 Å²	106	77.6 Å²	77.6	50%	0.495	37%	0.369	S	S	.	.			trans	-109.7	-16.2	-169.7	-75.4	158.9	169.7	0	0	116.4	N78 D82	N78-E80 PolarHBondContact O-N 3.01Å; E80-D82 PolarHBondContact O-N 3.24Å
81	C	64.9	Low	67.6	Low	29 Å²	29	72.2 Å²	72.2	20%	0.196	34%	0.339	C	S	.	.	H	α-helix	trans	-64.9	-42.1	-175	-177.2	0	0	0	0	112.8	C73 R83 A84 T85	C73-C81 VanDerWaalsContact CA-SG 3.52Å; C73-C81 HydrophobicContact CB-CB 4.4Å; C73-C81 WeakPolarHBondContact CB-SG 3.31Å; C73-C81 WeakPolarHBondContact SG-CB 3.4Å; C73-C81 CovalentContact SG-SG 2.02Å; C73-C81 PolarHBondContact SG-SG 3.43Å; C81-R83 VanDerWaalsContact C-N 3.27Å; C81-R83 PolarHBondContact O-N 3.29Å; C81-A84 PolarHBondContact O-N 3.05Å; C81-T85 WeakPolarHBondContact O-CG2 3.33Å; C81-T85 PolarHBondContact O-N 3.45Å
82	D	61.4	Low	68.5	Low	91 Å²	91	66.1 Å²	66.1	49%	0.487	32%	0.316	S	S	.	.	H	α-helix	trans	-59.6	-35.4	-175.2	-70.8	-16.6	0	0	0	113.1	E80 T85	E80-D82 PolarHBondContact O-N 3.24Å; D82-T85 PolarHBondContact O-OG1 3.37Å
83	R	61.8	Low	69.8	Low	89 Å²	89	66 Å²	66	34%	0.336	32%	0.316	S	S	.	.	H	α-helix	trans	-88	-27	-173.5	-59.7	-179	118.5	171.5	7.3	113.5	C81 L427	C81-R83 VanDerWaalsContact C-N 3.27Å; C81-R83 PolarHBondContact O-N 3.29Å; R83-L427 HydrophobicContact CB-CD2 3.41Å; R83-L427 VanDerWaalsContact CB-CD2 3.41Å; R83-L427 HydrophobicContact CG-CD2 4.35Å
84	A	66.1	Low	71.1	Confident	15 Å²	15	65.4 Å²	65.4	12%	0.124	31%	0.313	C	S	.	.	H	α-helix	trans	-99.1	1.5	-179.2	0	0	0	0	0	113.9	C81 G86 Y87 Q88	C81-A84 PolarHBondContact O-N 3.05Å; A84-G86 VanDerWaalsContact C-N 3.27Å; A84-G86 PolarHBondContact O-N 2.98Å; A84-Y87 PolarHBondContact O-N 2.93Å; A84-Q88 WeakPolarHBondContact O-CG 3.42Å; A84-Q88 PolarHBondContact O-N 3.28Å; A84-Q88 VanDerWaalsContact O-N 3.09Å
85	T	76.4	Confident	72.7	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-52.2	-41.9	-178.8	52.8	0	0	0	0	113.3	A67 F72 C81 D82 S89	A67-T85 HydrophobicContact CB-CG2 3.79Å; F72-T85 HydrophobicContact CD1-CG2 4.48Å; F72-T85 HydrophobicContact CE1-CG2 4.24Å; C81-T85 WeakPolarHBondContact O-CG2 3.33Å; C81-T85 PolarHBondContact O-N 3.45Å; D82-T85 PolarHBondContact O-OG1 3.37Å; T85-S89 WeakPolarHBondContact O-CB 3.49Å; T85-S89 PolarHBondContact O-N 3.12Å; T85-S89 PolarHBondContact O-OG 2.99Å
86	G	80	Confident	74.6	Confident	0 Å²	0	51.2 Å²	51.2	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-59.4	-57.4	179.1	0	0	0	0	0	112.9	A84 Q88 S89 V90	A84-G86 VanDerWaalsContact C-N 3.27Å; A84-G86 PolarHBondContact O-N 2.98Å; G86-Q88 VanDerWaalsContact C-N 3.34Å; G86-Q88 PolarHBondContact O-N 3.1Å; G86-S89 WeakPolarHBondContact O-CB 3.29Å; G86-S89 PolarHBondContact O-N 3.47Å; G86-S89 VanDerWaalsContact O-N 3.16Å; G86-V90 WeakPolarHBondContact O-CG2 3.32Å; G86-V90 PolarHBondContact O-N 3.34Å; G86-V90 VanDerWaalsContact O-N 3.14Å
87	Y	81.4	Confident	76.6	Confident	8 Å²	8	44.2 Å²	44.2	3%	0.031	22%	0.215	C	C	.	.	H	α-helix	trans	-60.2	-43.1	179.2	-68.6	-20	0	0	0	112.1	L58 A84 S89 V90 Y91 A328 G329 T417 N418 Y420 L430	L58-Y87 HydrophobicContact CD2-CD1 3.78Å; L58-Y87 HydrophobicContact CD2-CE1 3.92Å; A84-Y87 PolarHBondContact O-N 2.93Å; Y87-S89 VanDerWaalsContact C-N 3.26Å; Y87-S89 PolarHBondContact O-N 3.26Å; Y87-V90 WeakPolarHBondContact O-CB 3.47Å; Y87-V90 PolarHBondContact O-N 3.36Å; Y87-V90 VanDerWaalsContact O-N 3.16Å; Y87-Y91 WeakPolarHBondContact O-CD2 3.43Å; Y87-Y91 PolarHBondContact O-N 3.49Å; Y87-A328 HydrophobicContact CD1-CB 3.71Å; Y87-A328 HydrophobicContact CD2-CB 3.97Å; Y87-A328 HydrophobicContact CE1-CB 3.62Å; Y87-A328 HydrophobicContact CE2-CB 3.9Å; Y87-A328 HydrophobicContact CG-CB 3.87Å; Y87-G329 PolarHBondContact OH-O 3.44Å; Y87-G329 VanDerWaalsContact OH-O 3.13Å; Y87-T417 HydrophobicContact CD1-CG2 4.04Å; Y87-T417 HydrophobicContact CG-CG2 4.23Å; Y87-N418 PolarHBondContact OH-ND2 3.16Å; Y87-Y420 AromaticContact CD2-CD1 3.84Å; Y87-Y420 HydrophobicContact CD2-CD1 3.84Å; Y87-Y420 HydrophobicContact CD2-CG 4.15Å; Y87-Y420 HydrophobicContact CE2-CD1 4.27Å; Y87-Y420 HydrophobicContact CE2-CG 4.12Å; Y87-L430 HydrophobicContact CE2-CD2 3.91Å
88	Q	80.4	Confident	78.7	Confident	31 Å²	31	38 Å²	38	15%	0.145	18%	0.182	C	C	.	.	H	α-helix	trans	-62.2	-34.1	178.4	-68.8	-173.2	5.1	0	0	113	F72 A84 G86 R92 Y161	F72-Q88 HydrophobicContact CZ-CB 4.43Å; A84-Q88 WeakPolarHBondContact O-CG 3.42Å; A84-Q88 PolarHBondContact O-N 3.28Å; A84-Q88 VanDerWaalsContact O-N 3.09Å; G86-Q88 VanDerWaalsContact C-N 3.34Å; G86-Q88 PolarHBondContact O-N 3.1Å; Q88-R92 WeakPolarHBondContact O-CG 3.36Å; Q88-R92 PolarHBondContact O-N 2.76Å; Q88-Y161 VanDerWaalsContact NE2-CD2 3.31Å
89	S	85.8	Confident	80.9	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-66.6	-42.3	175.3	-56.8	0	0	0	0	111.6	L66 F72 T85 G86 Y87 Y91 R92 M93	L66-S89 WeakPolarHBondContact CD2-OG 3.22Å; F72-S89 VanDerWaalsContact CZ-OG 3.24Å; F72-S89 WeakPolarHBondContact CZ-OG 3.49Å; T85-S89 WeakPolarHBondContact O-CB 3.49Å; T85-S89 PolarHBondContact O-N 3.12Å; T85-S89 PolarHBondContact O-OG 2.99Å; G86-S89 WeakPolarHBondContact O-CB 3.29Å; G86-S89 PolarHBondContact O-N 3.47Å; G86-S89 VanDerWaalsContact O-N 3.16Å; Y87-S89 VanDerWaalsContact C-N 3.26Å; Y87-S89 PolarHBondContact O-N 3.26Å; S89-Y91 PolarHBondContact O-N 2.78Å; S89-R92 PolarHBondContact O-N 3.11Å; S89-M93 PolarHBondContact O-N 3.12Å
90	V	89.4	Confident	82.8	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-60.9	-44.7	176.1	175	0	0	0	0	111.1	L58 G86 Y87 R92 M93 C94 L416 T417	L58-V90 HydrophobicContact CD1-CG2 3.73Å; L58-V90 HydrophobicContact CD2-CG2 4.24Å; L58-V90 HydrophobicContact CG-CG2 3.75Å; G86-V90 WeakPolarHBondContact O-CG2 3.32Å; G86-V90 PolarHBondContact O-N 3.34Å; G86-V90 VanDerWaalsContact O-N 3.14Å; Y87-V90 WeakPolarHBondContact O-CB 3.47Å; Y87-V90 PolarHBondContact O-N 3.36Å; Y87-V90 VanDerWaalsContact O-N 3.16Å; V90-R92 VanDerWaalsContact C-N 3.3Å; V90-R92 PolarHBondContact O-N 3.37Å; V90-M93 PolarHBondContact O-N 3.48Å; V90-C94 VanDerWaalsContact O-CB 3.27Å; V90-C94 WeakPolarHBondContact O-CB 3.5Å; V90-C94 PolarHBondContact O-N 2.84Å; V90-C94 PolarHBondContact O-SG 2.78Å; V90-L416 HydrophobicContact CG1-CB 3.86Å; V90-L416 HydrophobicContact CG1-CD1 4.19Å; V90-T417 HydrophobicContact CB-CG2 4.11Å; V90-T417 HydrophobicContact CG1-CG2 3.9Å
91	Y	88.6	Confident	84.5	Confident	14 Å²	14	18.9 Å²	18.9	6%	0.055	9%	0.094	C	C	.	.	H	α-helix	trans	-56.3	-43.2	176.9	-87.3	-76.2	0	0	0	112.4	Y87 S89 F95 W168 L169 M413 T417	Y87-Y91 WeakPolarHBondContact O-CD2 3.43Å; Y87-Y91 PolarHBondContact O-N 3.49Å; S89-Y91 PolarHBondContact O-N 2.78Å; Y91-F95 VanDerWaalsContact O-CB 3.28Å; Y91-F95 WeakPolarHBondContact O-CB 3.49Å; Y91-F95 PolarHBondContact O-N 3.12Å; Y91-W168 AromaticContact CD1-CD1 3.67Å; Y91-W168 PolarHBondContact O-NE1 3.47Å; Y91-L169 HydrophobicContact CE1-CB 4.46Å; Y91-L169 WeakPolarHBondContact OH-CD1 3.46Å; Y91-M413 HydrophobicContact CD1-CE 4.06Å; Y91-M413 HydrophobicContact CD1-CG 3.83Å; Y91-M413 HydrophobicContact CD1-SD 3.38Å; Y91-M413 WeakPolarHBondContact CD1-SD 3.48Å; Y91-M413 HydrophobicContact CE1-CE 3.84Å; Y91-M413 HydrophobicContact CE1-CG 4.02Å; Y91-M413 HydrophobicContact CE1-SD 3.76Å; Y91-M413 HydrophobicContact CG-CG 4.42Å; Y91-M413 HydrophobicContact CG-SD 4.32Å; Y91-T417 HydrophobicContact CD2-CG2 4.02Å; Y91-T417 HydrophobicContact CE2-CG2 3.68Å
92	R	89.9	Confident	85.9	Confident	17 Å²	17	21.5 Å²	21.5	6%	0.064	10%	0.102	C	C	.	.	H	α-helix	trans	-72.3	-43	-179.5	-66.8	174.3	174.4	114.1	-6.2	112.5	F72 Q88 S89 V90 F95 A96 A156 I159	F72-R92 VanDerWaalsContact CE2-NH1 3.32Å; Q88-R92 WeakPolarHBondContact O-CG 3.36Å; Q88-R92 PolarHBondContact O-N 2.76Å; S89-R92 PolarHBondContact O-N 3.11Å; V90-R92 VanDerWaalsContact C-N 3.3Å; V90-R92 PolarHBondContact O-N 3.37Å; R92-F95 WeakPolarHBondContact O-CB 3.38Å; R92-F95 PolarHBondContact O-N 3.01Å; R92-A96 PolarHBondContact O-N 3.31Å; R92-A96 VanDerWaalsContact O-N 3.15Å; R92-A156 HydrophobicContact CB-CB 4.32Å; R92-A156 WeakPolarHBondContact CD-O 3.39Å; R92-A156 VanDerWaalsContact O-CB 3.3Å; R92-A156 WeakPolarHBondContact O-CB 3.47Å; R92-I159 PolarHBondContact NE-O 3.09Å; R92-I159 PolarHBondContact NH2-O 3.02Å
93	M	91.8	Very high	87.4	Confident	14 Å²	14	21.1 Å²	21.1	7%	0.069	10%	0.1	C	C	.	.	H	α-helix	trans	-63.7	-43.6	175.8	-177.2	59.5	-169.6	0	0	111.5	V53 S54 M57 S89 V90 A96 M97 A153	V53-M93 HydrophobicContact CB-CE 4.07Å; V53-M93 HydrophobicContact CG1-CE 3.94Å; V53-M93 HydrophobicContact CG1-CG 4.39Å; V53-M93 HydrophobicContact CG1-SD 4.15Å; S54-M93 VanDerWaalsContact OG-CG 3.24Å; S54-M93 WeakPolarHBondContact OG-CG 3.47Å; M57-M93 HydrophobicContact CE-CB 4.33Å; M57-M93 HydrophobicContact CE-CG 4.45Å; M57-M93 HydrophobicContact SD-CB 3.94Å; M57-M93 HydrophobicContact SD-CG 4.38Å; S89-M93 PolarHBondContact O-N 3.12Å; V90-M93 PolarHBondContact O-N 3.48Å; M93-A96 PolarHBondContact O-N 3Å; M93-M97 HydrophobicContact CE-CG 4.42Å; M93-M97 HydrophobicContact CG-CE 4.48Å; M93-M97 PolarHBondContact O-N 3.02Å; M93-M97 VanDerWaalsContact O-N 3.16Å; M93-A153 HydrophobicContact SD-CB 3.96Å
94	C	93.4	Very high	88.8	Confident	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-70	-32.9	177.5	-64.2	0	0	0	0	112.6	V90 A96 M97 A98 M413	V90-C94 VanDerWaalsContact O-CB 3.27Å; V90-C94 WeakPolarHBondContact O-CB 3.5Å; V90-C94 PolarHBondContact O-N 2.84Å; V90-C94 PolarHBondContact O-SG 2.78Å; C94-A96 VanDerWaalsContact C-N 3.33Å; C94-A96 PolarHBondContact O-N 3.25Å; C94-M97 HydrophobicContact CB-CE 4.14Å; C94-M97 PolarHBondContact O-N 3.17Å; C94-M97 VanDerWaalsContact SG-CE 3.6Å; C94-A98 VanDerWaalsContact O-CB 3.29Å; C94-A98 WeakPolarHBondContact O-CB 3.22Å; C94-A98 PolarHBondContact O-N 2.94Å; C94-M413 HydrophobicContact CB-CB 3.58Å; C94-M413 HydrophobicContact CB-CG 3.79Å; C94-M413 HydrophobicContact CB-SD 4.04Å
95	F	93.6	Very high	89.9	Confident	55 Å²	55	18 Å²	18	24%	0.241	9%	0.086	C	C	.	.	H	α-helix	trans	-57.9	-45.8	170.3	175.1	-100.4	0	0	0	111.8	Y91 R92 M97 A98 A99 A156 I159 F164 W168	Y91-F95 VanDerWaalsContact O-CB 3.28Å; Y91-F95 WeakPolarHBondContact O-CB 3.49Å; Y91-F95 PolarHBondContact O-N 3.12Å; R92-F95 WeakPolarHBondContact O-CB 3.38Å; R92-F95 PolarHBondContact O-N 3.01Å; F95-M97 PolarHBondContact O-N 3.28Å; F95-A98 PolarHBondContact O-N 2.67Å; F95-A99 VanDerWaalsContact O-CB 3.28Å; F95-A99 WeakPolarHBondContact O-CB 3.48Å; F95-A99 PolarHBondContact O-N 2.94Å; F95-A156 HydrophobicContact CD1-CB 3.83Å; F95-I159 HydrophobicContact CD1-CD1 4.12Å; F95-I159 HydrophobicContact CE1-CD1 3.9Å; F95-F164 HydrophobicContact CB-CZ 4.37Å; F95-F164 HydrophobicContact CD1-CZ 4.26Å; F95-F164 HydrophobicContact CD2-CE2 4.08Å; F95-F164 AromaticContact CD2-CZ 3.61Å; F95-F164 HydrophobicContact CD2-CZ 3.61Å; F95-F164 HydrophobicContact CE1-CZ 4.48Å; F95-F164 AromaticContact CE2-CE2 3.88Å; F95-F164 HydrophobicContact CE2-CE2 3.88Å; F95-F164 AromaticContact CE2-CZ 3.87Å; F95-F164 HydrophobicContact CE2-CZ 3.87Å; F95-F164 AromaticContact CG-CZ 3.82Å; F95-F164 HydrophobicContact CG-CZ 3.82Å; F95-F164 HydrophobicContact CZ-CE2 4.27Å; F95-F164 HydrophobicContact CZ-CZ 4.3Å; F95-W168 HydrophobicContact CB-CZ2 4.04Å; F95-W168 AromaticContact CD2-CD2 3.88Å; F95-W168 HydrophobicContact CD2-CD2 3.88Å; F95-W168 AromaticContact CD2-CE2 3.65Å; F95-W168 AromaticContact CD2-CE3 3.96Å; F95-W168 HydrophobicContact CD2-CE3 3.96Å; F95-W168 AromaticContact CD2-CH2 3.72Å; F95-W168 HydrophobicContact CD2-CH2 3.72Å; F95-W168 AromaticContact CD2-CZ2 3.63Å; F95-W168 HydrophobicContact CD2-CZ2 3.63Å; F95-W168 AromaticContact CD2-CZ3 3.87Å; F95-W168 HydrophobicContact CD2-CZ3 3.87Å; F95-W168 HydrophobicContact CE2-CE3 4.35Å; F95-W168 HydrophobicContact CE2-CH2 4.3Å; F95-W168 HydrophobicContact CE2-CZ3 4.15Å; F95-W168 HydrophobicContact CG-CZ2 4.3Å
96	A	94.7	Very high	90.6	Very high	1 Å²	1	22 Å²	22	1%	0.008	11%	0.107	C	C	.	.	H	α-helix	trans	-62.7	-42.5	177.8	0	0	0	0	0	112.8	R92 M93 C94 F100 L152 A153 A156	R92-A96 PolarHBondContact O-N 3.31Å; R92-A96 VanDerWaalsContact O-N 3.15Å; M93-A96 PolarHBondContact O-N 3Å; C94-A96 VanDerWaalsContact C-N 3.33Å; C94-A96 PolarHBondContact O-N 3.25Å; A96-F100 WeakPolarHBondContact O-CB 3.36Å; A96-F100 PolarHBondContact O-N 3.21Å; A96-L152 HydrophobicContact CB-CB 4.05Å; A96-A153 HydrophobicContact CB-CB 3.96Å; A96-A156 HydrophobicContact CB-CB 4.21Å
97	M	94.4	Very high	91	Very high	1 Å²	1	26.2 Å²	26.2	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-61.3	-48.1	173.9	-68.9	-170.4	-72.9	0	0	111.7	L47 G50 M93 C94 F95 F100 F101 L149	L47-M97 HydrophobicContact CD1-SD 4.42Å; G50-M97 WeakPolarHBondContact CA-SD 3.44Å; M93-M97 HydrophobicContact CE-CG 4.42Å; M93-M97 HydrophobicContact CG-CE 4.48Å; M93-M97 PolarHBondContact O-N 3.02Å; M93-M97 VanDerWaalsContact O-N 3.16Å; C94-M97 HydrophobicContact CB-CE 4.14Å; C94-M97 PolarHBondContact O-N 3.17Å; C94-M97 VanDerWaalsContact SG-CE 3.6Å; F95-M97 PolarHBondContact O-N 3.28Å; M97-F100 WeakPolarHBondContact O-CB 3.27Å; M97-F100 PolarHBondContact O-N 3.46Å; M97-F101 WeakPolarHBondContact O-CD2 3.24Å; M97-F101 PolarHBondContact O-N 3.33Å; M97-F101 VanDerWaalsContact O-N 3.08Å; M97-L149 HydrophobicContact CG-CD1 4.22Å
98	A	95.6	Very high	91.2	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-61.3	-48.4	179.6	0	0	0	0	0	111.2	C94 F95 F100 F101 F102 W168 F406 S409 L410	C94-A98 VanDerWaalsContact O-CB 3.29Å; C94-A98 WeakPolarHBondContact O-CB 3.22Å; C94-A98 PolarHBondContact O-N 2.94Å; F95-A98 PolarHBondContact O-N 2.67Å; A98-F100 VanDerWaalsContact C-N 3.31Å; A98-F100 PolarHBondContact O-N 3.26Å; A98-F101 PolarHBondContact O-N 3.37Å; A98-F102 WeakPolarHBondContact O-CB 3.33Å; A98-F102 PolarHBondContact O-N 3.47Å; A98-W168 HydrophobicContact CB-CH2 3.89Å; A98-W168 HydrophobicContact CB-CZ2 3.8Å; A98-F406 HydrophobicContact CB-CD2 3.87Å; A98-F406 HydrophobicContact CB-CE2 3.88Å; A98-F406 WeakPolarHBondContact O-CD2 3.37Å; A98-S409 VanDerWaalsContact CA-OG 3.23Å; A98-S409 WeakPolarHBondContact CA-OG 3.43Å; A98-S409 VanDerWaalsContact CB-OG 3.31Å; A98-S409 WeakPolarHBondContact CB-OG 3.33Å; A98-S409 PolarHBondContact N-OG 3.32Å; A98-L410 HydrophobicContact CB-CD2 4.09Å
99	A	94.9	Very high	91.4	Very high	20 Å²	20	28.6 Å²	28.6	17%	0.165	14%	0.143	C	C	.	.	H	α-helix	trans	-58.2	-43.1	176.7	0	0	0	0	0	111.7	F95 F102 I103	F95-A99 VanDerWaalsContact O-CB 3.28Å; F95-A99 WeakPolarHBondContact O-CB 3.48Å; F95-A99 PolarHBondContact O-N 2.94Å; A99-F102 PolarHBondContact O-N 3.21Å; A99-I103 WeakPolarHBondContact O-CB 3.27Å; A99-I103 WeakPolarHBondContact O-CD1 3.06Å; A99-I103 WeakPolarHBondContact O-CG1 3.38Å; A99-I103 PolarHBondContact O-N 3.09Å
100	F	95	Very high	91.2	Very high	11 Å²	11	37.6 Å²	37.6	5%	0.048	18%	0.177	C	C	.	.	H	α-helix	trans	-59.2	-51.8	177.7	179.1	-87.9	0	0	0	112.2	Y43 M46 A96 M97 A98 F102 I103 L104 K145 A148 L149 L152	Y43-F100 HydrophobicContact CE1-CE1 4.37Å; M46-F100 HydrophobicContact CE-CD1 3.46Å; M46-F100 VanDerWaalsContact CE-CD1 3.46Å; M46-F100 HydrophobicContact CE-CE1 3.1Å; M46-F100 HydrophobicContact CE-CZ 3.95Å; M46-F100 HydrophobicContact SD-CD1 4.32Å; M46-F100 HydrophobicContact SD-CE1 3.68Å; M46-F100 HydrophobicContact SD-CZ 3.9Å; A96-F100 WeakPolarHBondContact O-CB 3.36Å; A96-F100 PolarHBondContact O-N 3.21Å; M97-F100 WeakPolarHBondContact O-CB 3.27Å; M97-F100 PolarHBondContact O-N 3.46Å; A98-F100 VanDerWaalsContact C-N 3.31Å; A98-F100 PolarHBondContact O-N 3.26Å; F100-F102 VanDerWaalsContact C-N 3.34Å; F100-F102 PolarHBondContact O-N 3.21Å; F100-I103 PolarHBondContact O-N 2.92Å; F100-L104 HydrophobicContact CD1-CD1 4.05Å; F100-L104 HydrophobicContact CE1-CD1 3.27Å; F100-L104 HydrophobicContact CE1-CG 4.11Å; F100-L104 HydrophobicContact CZ-CD1 3.65Å; F100-L104 HydrophobicContact CZ-CG 4.32Å; F100-L104 PolarHBondContact O-N 3.43Å; F100-L104 VanDerWaalsContact O-N 3.1Å; F100-K145 HydrophobicContact CE2-CB 4.43Å; F100-K145 WeakPolarHBondContact CE2-O 3.11Å; F100-K145 HydrophobicContact CZ-CB 4.04Å; F100-K145 HydrophobicContact CZ-CG 4.33Å; F100-A148 HydrophobicContact CE2-CB 4.28Å; F100-L149 HydrophobicContact CB-CD1 3.81Å; F100-L149 HydrophobicContact CD2-CB 4.05Å; F100-L149 HydrophobicContact CD2-CD1 4.43Å; F100-L149 HydrophobicContact CE2-CB 4.35Å; F100-L149 HydrophobicContact CG-CB 4.44Å; F100-L149 HydrophobicContact CG-CD1 4.07Å; F100-L152 HydrophobicContact CB-CD1 3.91Å; F100-L152 HydrophobicContact CD2-CD1 4.24Å
101	F	94.5	Very high	90.8	Very high	1 Å²	1	38 Å²	38	0%	0.004	18%	0.18	C	C	.	.	H	α-helix	trans	-68.2	-33.6	179.3	-73.2	-66.3	0	0	0	112.5	Y43 M46 L47 M97 A98 L104 M105 H402 F405 F406	Y43-F101 HydrophobicContact CD1-CE1 4.08Å; M46-F101 HydrophobicContact CE-CD1 4.43Å; M46-F101 HydrophobicContact CE-CE1 3.5Å; M46-F101 VanDerWaalsContact CE-CE1 3.5Å; M46-F101 HydrophobicContact CE-CE2 3.9Å; M46-F101 HydrophobicContact CE-CZ 3.17Å; L47-F101 HydrophobicContact CB-CE2 4.15Å; L47-F101 HydrophobicContact CB-CZ 4.01Å; L47-F101 HydrophobicContact CD1-CE2 3.8Å; L47-F101 HydrophobicContact CD1-CZ 4.47Å; L47-F101 HydrophobicContact CG-CE2 4.47Å; M97-F101 WeakPolarHBondContact O-CD2 3.24Å; M97-F101 PolarHBondContact O-N 3.33Å; M97-F101 VanDerWaalsContact O-N 3.08Å; A98-F101 PolarHBondContact O-N 3.37Å; F101-L104 PolarHBondContact O-N 2.88Å; F101-M105 WeakPolarHBondContact O-CB 3.29Å; F101-M105 PolarHBondContact O-N 2.9Å; F101-H402 AromaticContact CD1-ND1 3.98Å; F101-F405 HydrophobicContact CB-CB 4.38Å; F101-F405 HydrophobicContact CD1-CB 3.57Å; F101-F405 HydrophobicContact CD1-CD1 4.25Å; F101-F405 HydrophobicContact CD1-CG 4.3Å; F101-F405 HydrophobicContact CD2-CB 4.18Å; F101-F405 HydrophobicContact CE1-CB 3.77Å; F101-F405 AromaticContact CE1-CD1 3.55Å; F101-F405 HydrophobicContact CE1-CD1 3.55Å; F101-F405 HydrophobicContact CE1-CG 4.04Å; F101-F405 HydrophobicContact CE2-CB 4.37Å; F101-F405 HydrophobicContact CE2-CD1 4.4Å; F101-F405 HydrophobicContact CG-CB 3.79Å; F101-F405 HydrophobicContact CZ-CB 4.16Å; F101-F405 AromaticContact CZ-CD1 3.63Å; F101-F405 HydrophobicContact CZ-CD1 3.63Å; F101-F405 HydrophobicContact CZ-CG 4.39Å; F101-F406 HydrophobicContact CB-CB 4.04Å
102	F	94.5	Very high	90.1	Very high	84 Å²	84	45.5 Å²	45.5	37%	0.368	21%	0.208	S	C	.	.	H	α-helix	trans	-66.7	-41.4	175.9	-171.7	-101.6	0	0	0	112.4	A98 A99 F100 M105 I106 F406	A98-F102 WeakPolarHBondContact O-CB 3.33Å; A98-F102 PolarHBondContact O-N 3.47Å; A99-F102 PolarHBondContact O-N 3.21Å; F100-F102 VanDerWaalsContact C-N 3.34Å; F100-F102 PolarHBondContact O-N 3.21Å; F102-M105 HydrophobicContact CD2-CE 3.54Å; F102-M105 HydrophobicContact CD2-SD 4.4Å; F102-M105 HydrophobicContact CE2-CE 3.36Å; F102-M105 HydrophobicContact CG-CE 4.35Å; F102-M105 HydrophobicContact CZ-CE 4.04Å; F102-M105 WeakPolarHBondContact O-CB 3.23Å; F102-M105 PolarHBondContact O-N 3.32Å; F102-I106 HydrophobicContact CD1-CD1 3.87Å; F102-I106 HydrophobicContact CE1-CD1 3.46Å; F102-I106 VanDerWaalsContact CE1-CD1 3.46Å; F102-I106 HydrophobicContact CE1-CG1 4.38Å; F102-I106 HydrophobicContact CZ-CD1 4.04Å; F102-I106 WeakPolarHBondContact O-CG1 3.36Å; F102-I106 PolarHBondContact O-N 3.17Å; F102-F406 HydrophobicContact CB-CD2 3.85Å; F102-F406 HydrophobicContact CB-CE2 4.11Å; F102-F406 HydrophobicContact CB-CG 4.43Å; F102-F406 HydrophobicContact CD2-CD1 4.4Å; F102-F406 HydrophobicContact CD2-CD2 4.24Å; F102-F406 HydrophobicContact CD2-CE1 4.29Å; F102-F406 HydrophobicContact CD2-CE2 4.1Å; F102-F406 HydrophobicContact CD2-CG 4.37Å; F102-F406 HydrophobicContact CD2-CZ 4.12Å; F102-F406 HydrophobicContact CG-CD2 4.48Å; F102-F406 HydrophobicContact CG-CE2 4.39Å
103	I	93.5	Very high	89.1	Confident	83 Å²	83	45.9 Å²	45.9	43%	0.426	21%	0.213	S	C	.	.	H	α-helix	trans	-63.2	-44.7	174.4	-69.3	164.1	0	0	0	110.1	A99 F100 M105 I106 L107	A99-I103 WeakPolarHBondContact O-CB 3.27Å; A99-I103 WeakPolarHBondContact O-CD1 3.06Å; A99-I103 WeakPolarHBondContact O-CG1 3.38Å; A99-I103 PolarHBondContact O-N 3.09Å; F100-I103 PolarHBondContact O-N 2.92Å; I103-M105 VanDerWaalsContact C-N 3.32Å; I103-M105 PolarHBondContact O-N 2.96Å; I103-I106 PolarHBondContact O-N 3.34Å; I103-L107 HydrophobicContact CG2-CD1 3.94Å; I103-L107 HydrophobicContact CG2-CG 4.37Å; I103-L107 WeakPolarHBondContact O-CG 3.46Å; I103-L107 PolarHBondContact O-N 3.38Å
104	L	90.4	Very high	88.1	Confident	11 Å²	11	46.1 Å²	46.1	6%	0.058	22%	0.216	C	C	.	.	H	α-helix	trans	-63.4	-36.8	175.7	-72.8	-175.3	0	0	0	112.8	Y43 F100 F101 I106 L107 M108	Y43-L104 HydrophobicContact CD1-CD1 4.46Å; Y43-L104 HydrophobicContact CE1-CD1 3.53Å; F100-L104 HydrophobicContact CD1-CD1 4.05Å; F100-L104 HydrophobicContact CE1-CD1 3.27Å; F100-L104 HydrophobicContact CE1-CG 4.11Å; F100-L104 HydrophobicContact CZ-CD1 3.65Å; F100-L104 HydrophobicContact CZ-CG 4.32Å; F100-L104 PolarHBondContact O-N 3.43Å; F100-L104 VanDerWaalsContact O-N 3.1Å; F101-L104 PolarHBondContact O-N 2.88Å; L104-I106 PolarHBondContact O-N 2.89Å; L104-L107 HydrophobicContact CD2-CD1 4.41Å; L104-L107 PolarHBondContact O-N 2.95Å; L104-M108 WeakPolarHBondContact O-CB 3.42Å; L104-M108 WeakPolarHBondContact O-CG 3.3Å; L104-M108 PolarHBondContact O-N 3.41Å
105	M	89.5	Confident	86.9	Confident	26 Å²	26	53.6 Å²	53.6	13%	0.128	25%	0.248	C	C	.	.	H	α-helix	trans	-57.2	-49.1	173.1	180	-162.8	73.9	0	0	110.8	F101 F102 I103 M108 L109 S399 H402 F403	F101-M105 WeakPolarHBondContact O-CB 3.29Å; F101-M105 PolarHBondContact O-N 2.9Å; F102-M105 HydrophobicContact CD2-CE 3.54Å; F102-M105 HydrophobicContact CD2-SD 4.4Å; F102-M105 HydrophobicContact CE2-CE 3.36Å; F102-M105 HydrophobicContact CG-CE 4.35Å; F102-M105 HydrophobicContact CZ-CE 4.04Å; F102-M105 WeakPolarHBondContact O-CB 3.23Å; F102-M105 PolarHBondContact O-N 3.32Å; I103-M105 VanDerWaalsContact C-N 3.32Å; I103-M105 PolarHBondContact O-N 2.96Å; M105-M108 PolarHBondContact O-N 3.35Å; M105-L109 PolarHBondContact O-N 3.31Å; M105-S399 WeakPolarHBondContact CG-OG 3.44Å; M105-S399 PolarHBondContact O-OG 2.99Å; M105-H402 HydrophobicContact CB-CB 3.88Å; M105-F403 HydrophobicContact CG-CB 4.23Å; M105-F403 HydrophobicContact SD-CB 3.79Å; M105-F403 HydrophobicContact SD-CD2 3.62Å; M105-F403 HydrophobicContact SD-CG 4.13Å
106	I	92.1	Very high	86.1	Confident	84 Å²	84	53.2 Å²	53.2	43%	0.431	25%	0.249	S	C	.	.	H	α-helix	trans	-63.3	-45.1	178.9	-66.3	171.6	0	0	0	111.3	F102 I103 L104 M108 L109	F102-I106 HydrophobicContact CD1-CD1 3.87Å; F102-I106 HydrophobicContact CE1-CD1 3.46Å; F102-I106 VanDerWaalsContact CE1-CD1 3.46Å; F102-I106 HydrophobicContact CE1-CG1 4.38Å; F102-I106 HydrophobicContact CZ-CD1 4.04Å; F102-I106 WeakPolarHBondContact O-CG1 3.36Å; F102-I106 PolarHBondContact O-N 3.17Å; I103-I106 PolarHBondContact O-N 3.34Å; L104-I106 PolarHBondContact O-N 2.89Å; I106-M108 PolarHBondContact O-N 3.46Å; I106-L109 HydrophobicContact CG2-CD1 4.37Å; I106-L109 WeakPolarHBondContact O-CB 3.47Å; I106-L109 WeakPolarHBondContact O-CG 3.25Å; I106-L109 PolarHBondContact O-N 2.8Å
107	L	88.1	Confident	85.1	Confident	90 Å²	90	57.7 Å²	57.7	47%	0.471	28%	0.278	S	S	.	.	H	α-helix	trans	-62.9	-29.2	-179.7	-70.7	174.2	0	0	0	112.9	I103 L104	I103-L107 HydrophobicContact CG2-CD1 3.94Å; I103-L107 HydrophobicContact CG2-CG 4.37Å; I103-L107 WeakPolarHBondContact O-CG 3.46Å; I103-L107 PolarHBondContact O-N 3.38Å; L104-L107 HydrophobicContact CD2-CD1 4.41Å; L104-L107 PolarHBondContact O-N 2.95Å
108	M	84.6	Confident	84.4	Confident	1 Å²	1	62.5 Å²	62.5	1%	0.005	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.9	10	-178.5	-61.5	-59.7	165.1	0	0	114	L104 M105 I106 R110 V111 R118 V121 Q122 Y398	L104-M108 WeakPolarHBondContact O-CB 3.42Å; L104-M108 WeakPolarHBondContact O-CG 3.3Å; L104-M108 PolarHBondContact O-N 3.41Å; M105-M108 PolarHBondContact O-N 3.35Å; I106-M108 PolarHBondContact O-N 3.46Å; M108-R110 PolarHBondContact O-N 2.97Å; M108-V111 HydrophobicContact SD-CG2 4.31Å; M108-R118 WeakPolarHBondContact CE-O 3.23Å; M108-V121 HydrophobicContact CE-CB 3.89Å; M108-V121 HydrophobicContact CE-CG1 3.83Å; M108-Q122 HydrophobicContact CE-CB 3.69Å; M108-Q122 HydrophobicContact SD-CB 4.03Å; M108-Y398 HydrophobicContact SD-CD2 4.3Å
109	L	85.3	Confident	83.4	Confident	88 Å²	88	62.5 Å²	62.5	46%	0.461	30%	0.296	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.6	126.3	176.3	-72.9	171.4	0	0	0	111.5	M105 I106 V111 R118 S399	M105-L109 PolarHBondContact O-N 3.31Å; I106-L109 HydrophobicContact CG2-CD1 4.37Å; I106-L109 WeakPolarHBondContact O-CB 3.47Å; I106-L109 WeakPolarHBondContact O-CG 3.25Å; I106-L109 PolarHBondContact O-N 2.8Å; L109-V111 VanDerWaalsContact C-N 3.31Å; L109-V111 PolarHBondContact O-N 3.33Å; L109-R118 PolarHBondContact O-NH1 3.45Å; L109-S399 WeakPolarHBondContact CD2-OG 3.33Å
110	R	82.3	Confident	82.2	Confident	189 Å²	189	65.6 Å²	65.6	71%	0.713	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.8	38.3	174.9	-162.7	-177.6	171.1	162	-2.1	113.4	M108 R118	M108-R110 PolarHBondContact O-N 2.97Å; R110-R118 PolarHBondContact O-NH2 3.3Å
111	V	79.4	Confident	81.4	Confident	9 Å²	9	67.3 Å²	67.3	6%	0.055	32%	0.317	C	S	.	.			trans	-78	124.2	163.4	177.4	0	0	0	0	107.8	M108 L109 D116 R118 A119 V394 Y398	M108-V111 HydrophobicContact SD-CG2 4.31Å; L109-V111 VanDerWaalsContact C-N 3.31Å; L109-V111 PolarHBondContact O-N 3.33Å; V111-D116 HydrophobicContact CG1-CB 4.16Å; V111-R118 HydrophobicContact CG2-CB 3.97Å; V111-A119 HydrophobicContact CG1-CB 4.12Å; V111-V394 HydrophobicContact CG1-CG1 4.39Å; V111-Y398 HydrophobicContact CB-CD2 4.12Å; V111-Y398 HydrophobicContact CG1-CD2 3.84Å; V111-Y398 HydrophobicContact CG1-CE2 3.82Å
112	R	74	Confident	80.5	Confident	171 Å²	171	67.3 Å²	67.3	65%	0.645	32%	0.317	S	S	*	.			trans	-112.8	-22.5	-174.3	-69.8	-174.6	175.3	-177.6	-3.9	113.5	D116 V394	R112-D116 PolarHBondContact N-OD2 3.21Å; R112-V394 PolarHBondContact O-N 3.01Å
113	S	70.6	Confident	79.2	Confident	25 Å²	25	65 Å²	65	18%	0.175	31%	0.308	C	S	.	.	S	Bend	trans	-140	150.5	-178.2	174.4	0	0	0	0	110.5	K115 D116	S113-K115 PolarHBondContact O-N 3.35Å; S113-K115 VanDerWaalsContact O-N 3.15Å; S113-K115 PolarHBondContact OG-N 3.26Å; S113-D116 WeakPolarHBondContact O-CB 3.36Å; S113-D116 PolarHBondContact O-N 3.15Å
114	S	69.5	Low	77.6	Confident	18 Å²	18	61.4 Å²	61.4	13%	0.126	29%	0.293	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.6	-15.8	173.5	74.1	0	0	0	0	113.5	D116 A119 D388 E390 S391	S114-D116 VanDerWaalsContact C-N 3.31Å; S114-A119 WeakPolarHBondContact O-CB 3.35Å; S114-D388 PolarHBondContact OG-OD2 3.33Å; S114-D388 VanDerWaalsContact OG-OD2 3.08Å; S114-E390 VanDerWaalsContact CB-O 3.27Å; S114-E390 WeakPolarHBondContact CB-O 3.38Å; S114-E390 PolarHBondContact N-O 2.74Å; S114-E390 PolarHBondContact OG-O 3.44Å; S114-E390 VanDerWaalsContact OG-O 3.07Å; S114-S391 WeakPolarHBondContact OG-CA 3.38Å
115	K	69	Low	75.6	Confident	157 Å²	157	64 Å²	64	68%	0.683	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.6	-17.4	177.5	-62.4	-179.5	-175.5	173.3	0	113.5	S113	S113-K115 PolarHBondContact O-N 3.35Å; S113-K115 VanDerWaalsContact O-N 3.15Å; S113-K115 PolarHBondContact OG-N 3.26Å
116	D	75.8	Confident	73.5	Confident	47 Å²	47	67.8 Å²	67.8	25%	0.251	33%	0.327	S	S	.	.	S	Bend	trans	-60.3	138.8	178.1	-78	-27.6	0	0	0	110.2	V111 R112 S113 S114 R118 A119	V111-D116 HydrophobicContact CG1-CB 4.16Å; R112-D116 PolarHBondContact N-OD2 3.21Å; S113-D116 WeakPolarHBondContact O-CB 3.36Å; S113-D116 PolarHBondContact O-N 3.15Å; S114-D116 VanDerWaalsContact C-N 3.31Å; D116-R118 PolarHBondContact O-N 2.95Å; D116-R118 IonicContact OD2-NH2 2.74Å; D116-A119 HydrophobicContact CB-CB 4.45Å; D116-A119 WeakPolarHBondContact O-CB 3.12Å; D116-A119 PolarHBondContact O-N 3.39Å
117	P	74.9	Confident	70.9	Confident	95 Å²	95	67.4 Å²	67.4	62%	0.617	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.5	-24.6	180	23.5	-33.5	0	0	0	112.7	K120	P117-K120 WeakPolarHBondContact O-CB 2.93Å; P117-K120 PolarHBondContact O-N 2.91Å
118	R	79.7	Confident	68.2	Low	102 Å²	102	67.5 Å²	67.5	39%	0.385	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.1	-31.7	175.9	-64	173.2	-68.7	160.7	7.2	112.6	M108 L109 R110 V111 D116 K120 V121 Q122	M108-R118 WeakPolarHBondContact CE-O 3.23Å; L109-R118 PolarHBondContact O-NH1 3.45Å; R110-R118 PolarHBondContact O-NH2 3.3Å; V111-R118 HydrophobicContact CG2-CB 3.97Å; D116-R118 PolarHBondContact O-N 2.95Å; D116-R118 IonicContact OD2-NH2 2.74Å; R118-K120 PolarHBondContact O-N 3.29Å; R118-V121 WeakPolarHBondContact O-CB 3.29Å; R118-V121 PolarHBondContact O-N 2.94Å; R118-Q122 PolarHBondContact O-N 3.42Å
119	A	73.5	Confident	66	Low	1 Å²	1	71.8 Å²	71.8	1%	0.008	36%	0.362	C	S	.	.	H	α-helix	trans	-64.2	-25.3	173.6	0	0	0	0	0	111.7	V111 S114 D116 V121 Q122 N123 Y398	V111-A119 HydrophobicContact CG1-CB 4.12Å; S114-A119 WeakPolarHBondContact O-CB 3.35Å; D116-A119 HydrophobicContact CB-CB 4.45Å; D116-A119 WeakPolarHBondContact O-CB 3.12Å; D116-A119 PolarHBondContact O-N 3.39Å; A119-V121 VanDerWaalsContact C-N 3.31Å; A119-V121 PolarHBondContact O-N 3.44Å; A119-Q122 WeakPolarHBondContact O-CB 3.35Å; A119-Q122 PolarHBondContact O-N 2.87Å; A119-Q122 VanDerWaalsContact O-N 3.14Å; A119-N123 PolarHBondContact O-N 3.06Å; A119-Y398 HydrophobicContact CB-CE2 4.1Å
120	K	70.7	Confident	63.7	Low	85 Å²	85	74.6 Å²	74.6	37%	0.37	38%	0.377	S	S	.	.	H	α-helix	trans	-65.8	-30.6	171.8	-59.2	169.3	167.5	-172.5	0	112.7	P117 R118 Q122 G124 L125	P117-K120 WeakPolarHBondContact O-CB 2.93Å; P117-K120 PolarHBondContact O-N 2.91Å; R118-K120 PolarHBondContact O-N 3.29Å; K120-Q122 VanDerWaalsContact C-N 3.34Å; K120-G124 CarbonylContact O-C 3.57Å; K120-G124 WeakPolarHBondContact O-CA 3.33Å; K120-G124 PolarHBondContact O-N 3.22Å; K120-L125 HydrophobicContact CB-CD1 3.95Å; K120-L125 HydrophobicContact CD-CD1 3.56Å; K120-L125 HydrophobicContact CG-CD1 4.09Å
121	V	76.9	Confident	61.8	Low	47 Å²	47	73.5 Å²	73.5	29%	0.285	38%	0.378	S	S	.	.	H	α-helix	trans	-70	-35.1	172.5	174.2	0	0	0	0	110.2	M108 R118 A119 F141 K145	M108-V121 HydrophobicContact CE-CB 3.89Å; M108-V121 HydrophobicContact CE-CG1 3.83Å; R118-V121 WeakPolarHBondContact O-CB 3.29Å; R118-V121 PolarHBondContact O-N 2.94Å; A119-V121 VanDerWaalsContact C-N 3.31Å; A119-V121 PolarHBondContact O-N 3.44Å; V121-F141 HydrophobicContact CB-CE1 4.11Å; V121-F141 HydrophobicContact CB-CZ 4.35Å; V121-F141 HydrophobicContact CG1-CE1 3.58Å; V121-F141 HydrophobicContact CG1-CZ 3.85Å; V121-F141 HydrophobicContact CG2-CZ 4.28Å; V121-F141 WeakPolarHBondContact O-CE1 3.33Å; V121-K145 WeakPolarHBondContact O-CE 3.13Å; V121-K145 PolarHBondContact O-NZ 3.29Å
122	Q	76.9	Confident	59.8	Low	0 Å²	0	76.4 Å²	76.4	0%	0	41%	0.409	C	S	.	.	H	α-helix	trans	-68.6	-59	177.5	-174.4	74.3	-3.8	0	0	111.2	T39 Y43 M108 R118 A119 K120 K145 Y398 H402	T39-Q122 HydrophobicContact CG2-CG 4.16Å; Y43-Q122 PolarHBondContact OH-OE1 3.43Å; M108-Q122 HydrophobicContact CE-CB 3.69Å; M108-Q122 HydrophobicContact SD-CB 4.03Å; R118-Q122 PolarHBondContact O-N 3.42Å; A119-Q122 WeakPolarHBondContact O-CB 3.35Å; A119-Q122 PolarHBondContact O-N 2.87Å; A119-Q122 VanDerWaalsContact O-N 3.14Å; K120-Q122 VanDerWaalsContact C-N 3.34Å; Q122-K145 PolarHBondContact O-NZ 2.69Å; Q122-Y398 HydrophobicContact CB-CD2 4.34Å; Q122-Y398 HydrophobicContact CB-CE2 4.24Å; Q122-Y398 HydrophobicContact CG-CD2 4Å; Q122-Y398 HydrophobicContact CG-CE2 4Å; Q122-Y398 HydrophobicContact CG-CG 4.36Å; Q122-H402 PolarHBondContact NE2-NE2 3.46Å; Q122-H402 PolarHBondContact OE1-NE2 3.09Å
123	N	66.5	Low	58	Low	35 Å²	35	74.9 Å²	74.9	19%	0.187	41%	0.411	C	S	.	.	H	α-helix	trans	-92.8	-10.1	-169.3	-66.1	-24.8	0	0	0	114	T39 A119 Y398	T39-N123 PolarHBondContact OG1-OD1 3.14Å; A119-N123 PolarHBondContact O-N 3.06Å; N123-Y398 PolarHBondContact ND2-OH 3.43Å
124	G	60.7	Low	56.8	Low	9 Å²	9	78.8 Å²	78.8	9%	0.093	43%	0.433	C	S	.	.			trans	92.8	148.2	-171.8	0	0	0	0	0	112	K120 D126	K120-G124 CarbonylContact O-C 3.57Å; K120-G124 WeakPolarHBondContact O-CA 3.33Å; K120-G124 PolarHBondContact O-N 3.22Å; G124-D126 PolarHBondContact O-N 3.02Å
125	L	47.2	Very low	55.2	Low	66 Å²	66	84.2 Å²	84.2	35%	0.346	46%	0.457	S	S	.	.			trans	-80.1	103.3	-177.7	-171.8	75.1	0	0	0	110.5	K120 S127 L128	K120-L125 HydrophobicContact CB-CD1 3.95Å; K120-L125 HydrophobicContact CD-CD1 3.56Å; K120-L125 HydrophobicContact CG-CD1 4.09Å; L125-S127 PolarHBondContact O-N 3.02Å; L125-L128 HydrophobicContact CD2-CB 4.37Å
126	D	46.4	Very low	53.4	Low	105 Å²	105	86 Å²	86	56%	0.561	46%	0.459	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.2	-2	173.8	-133.8	7.4	0	0	0	113.3	G124 R138	G124-D126 PolarHBondContact O-N 3.02Å; D126-R138 IonicContact OD1-CZ 3.3Å; D126-R138 VanDerWaalsContact OD1-CZ 3.24Å; D126-R138 IonicContact OD1-NE 3.56Å; D126-R138 PolarHBondContact OD1-NE 2.92Å; D126-R138 IonicContact OD1-NH2 2.67Å; D126-R138 PolarHBondContact OD1-NH2 3.4Å; D126-R138 IonicContact OD2-CZ 3.24Å; D126-R138 IonicContact OD2-NE 2.7Å; D126-R138 IonicContact OD2-NH2 2.9Å; D126-R138 PolarHBondContact OD2-NH2 3.01Å; D126-R138 VanDerWaalsContact OD2-NH2 3.16Å
127	S	36.1	Very low	51.4	Low	75 Å²	75	85.1 Å²	85.1	52%	0.524	46%	0.457	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.3	3	-164.4	-168.5	0	0	0	0	115.8	L125 S129	L125-S127 PolarHBondContact O-N 3.02Å; S127-S129 PolarHBondContact O-N 3.13Å; S127-S129 VanDerWaalsContact O-N 3.09Å
128	L	32.3	Very low	49.8	Very low	92 Å²	92	86 Å²	86	48%	0.482	45%	0.448	S	S	.	.			trans	-86.8	60.3	170.7	-159.6	76	0	0	0	110.2	L125 L130	L125-L128 HydrophobicContact CD2-CB 4.37Å; L128-L130 PolarHBondContact O-N 3.21Å
129	S	38.5	Very low	48	Very low	91 Å²	91	84.1 Å²	84.1	64%	0.636	45%	0.45	S	S	*	.	G	3₁₀ helix	trans	-77.6	-2.4	172	53.8	0	0	0	0	113.1	S127 F131	S127-S129 PolarHBondContact O-N 3.13Å; S127-S129 VanDerWaalsContact O-N 3.09Å; S129-F131 VanDerWaalsContact C-N 3.26Å; S129-F131 PolarHBondContact O-N 2.87Å
130	L	36.1	Very low	46.7	Very low	148 Å²	148	85.7 Å²	85.7	78%	0.775	46%	0.461	S	S	*	.	G	3₁₀ helix	trans	-75.2	-6.9	-170.9	-140.2	102.4	0	0	0	115	L128	L128-L130 PolarHBondContact O-N 3.21Å
131	F	42.8	Very low	46.3	Very low	166 Å²	166	85.1 Å²	85.1	73%	0.728	46%	0.458	S	S	*	.	G	3₁₀ helix	trans	-124.5	12.4	-174.4	-93.2	-82.8	0	0	0	115.4	S129 M133	S129-F131 VanDerWaalsContact C-N 3.26Å; S129-F131 PolarHBondContact O-N 2.87Å; F131-M133 PolarHBondContact O-N 3.44Å
132	G	38.7	Very low	45.9	Very low	69 Å²	69	84.7 Å²	84.7	71%	0.711	45%	0.452	S	S	*	.	S	Bend	trans	63	5.6	174	0	0	0	0	0	116
133	M	35.3	Very low	45.5	Very low	140 Å²	140	90.9 Å²	90.9	69%	0.69	48%	0.479	S	S	*	.			trans	-102.7	74.2	171.5	-74	-171.1	-168.4	0	0	110.3	F131 Q135	F131-M133 PolarHBondContact O-N 3.44Å; M133-Q135 VanDerWaalsContact C-N 3.29Å; M133-Q135 PolarHBondContact O-N 3.09Å
134	V	44.5	Very low	46.2	Very low	106 Å²	106	95 Å²	95	64%	0.642	50%	0.495	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.3	-23	-171.5	178.6	0	0	0	0	113.4
135	Q	37.2	Very low	47.3	Very low	133 Å²	133	95 Å²	95	62%	0.621	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-26.5	-173.4	-158.6	105.3	-33.9	0	0	114.4	M133	M133-Q135 VanDerWaalsContact C-N 3.29Å; M133-Q135 PolarHBondContact O-N 3.09Å
136	W	31.2	Very low	49.1	Very low	194 Å²	194	94.8 Å²	94.8	74%	0.735	49%	0.488	S	S	*	.	H	α-helix	trans	-79.2	-28	-170.4	-108.9	74.4	0	0	0	114.2	S140	W136-S140 WeakPolarHBondContact O-CB 3.4Å; W136-S140 PolarHBondContact O-N 3.28Å; W136-S140 PolarHBondContact O-OG 3.3Å
137	S	33.7	Very low	51.1	Low	28 Å²	28	95.9 Å²	95.9	20%	0.196	49%	0.488	C	S	.	.	H	α-helix	trans	-74.9	-29.2	-170.3	-74.8	0	0	0	0	115
138	R	40	Very low	53.6	Low	114 Å²	114	94.2 Å²	94.2	43%	0.43	48%	0.478	S	S	.	.	H	α-helix	trans	-72.7	-40.8	174.8	-77.4	-173.3	-141.9	162.6	2	112.6	D126	D126-R138 IonicContact OD1-CZ 3.3Å; D126-R138 VanDerWaalsContact OD1-CZ 3.24Å; D126-R138 IonicContact OD1-NE 3.56Å; D126-R138 PolarHBondContact OD1-NE 2.92Å; D126-R138 IonicContact OD1-NH2 2.67Å; D126-R138 PolarHBondContact OD1-NH2 3.4Å; D126-R138 IonicContact OD2-CZ 3.24Å; D126-R138 IonicContact OD2-NE 2.7Å; D126-R138 IonicContact OD2-NH2 2.9Å; D126-R138 PolarHBondContact OD2-NH2 3.01Å; D126-R138 VanDerWaalsContact OD2-NH2 3.16Å
139	C	43	Very low	56.4	Low	63 Å²	63	90.4 Å²	90.4	43%	0.426	46%	0.458	S	S	.	.	H	α-helix	trans	-72.5	-32.4	176.8	-68.5	0	0	0	0	112.6	F141 W142 F143	C139-F141 VanDerWaalsContact C-N 3.32Å; C139-F141 PolarHBondContact O-N 3.31Å; C139-W142 PolarHBondContact O-N 2.97Å; C139-F143 PolarHBondContact O-N 2.59Å
140	S	45.7	Very low	58.9	Low	34 Å²	34	91.1 Å²	91.1	24%	0.238	45%	0.454	C	S	.	.	H	α-helix	trans	-57.3	-42.1	-175.7	-70.6	0	0	0	0	112.8	W136 F143 F144	W136-S140 WeakPolarHBondContact O-CB 3.4Å; W136-S140 PolarHBondContact O-N 3.28Å; W136-S140 PolarHBondContact O-OG 3.3Å; S140-F143 WeakPolarHBondContact O-CB 3.32Å; S140-F143 PolarHBondContact O-N 2.82Å; S140-F144 WeakPolarHBondContact O-CD2 3.5Å; S140-F144 PolarHBondContact O-N 3.07Å; S140-F144 VanDerWaalsContact O-N 3.16Å
141	F	62.2	Low	61.6	Low	73 Å²	73	86.5 Å²	86.5	32%	0.32	44%	0.437	S	S	.	.	H	α-helix	trans	-76.5	-28.1	-177	-153.6	-98.9	0	0	0	113.4	V121 C139 F144 K145	V121-F141 HydrophobicContact CB-CE1 4.11Å; V121-F141 HydrophobicContact CB-CZ 4.35Å; V121-F141 HydrophobicContact CG1-CE1 3.58Å; V121-F141 HydrophobicContact CG1-CZ 3.85Å; V121-F141 HydrophobicContact CG2-CZ 4.28Å; V121-F141 WeakPolarHBondContact O-CE1 3.33Å; C139-F141 VanDerWaalsContact C-N 3.32Å; C139-F141 PolarHBondContact O-N 3.31Å; F141-F144 HydrophobicContact CD2-CD2 4.49Å; F141-F144 PolarHBondContact O-N 2.87Å; F141-K145 HydrophobicContact CD1-CD 4.49Å; F141-K145 HydrophobicContact CD1-CG 4.47Å; F141-K145 HydrophobicContact CE1-CG 4.44Å; F141-K145 WeakPolarHBondContact O-CG 3.43Å; F141-K145 PolarHBondContact O-N 3.44Å; F141-K145 VanDerWaalsContact O-N 3.08Å
142	W	68.1	Low	64	Low	38 Å²	38	81.5 Å²	81.5	14%	0.144	42%	0.417	C	S	.	.	H	α-helix	trans	-68.4	-39.4	170.3	-74	102.8	0	0	0	111.7	T39 M42 Y43 C139 F144 K145 Y146	T39-W142 HydrophobicContact CG2-CH2 3.93Å; T39-W142 HydrophobicContact CG2-CZ2 3.83Å; M42-W142 HydrophobicContact CB-CD2 4.39Å; M42-W142 HydrophobicContact CB-CE3 3.98Å; M42-W142 HydrophobicContact CB-CH2 3.38Å; M42-W142 HydrophobicContact CB-CZ2 3.83Å; M42-W142 HydrophobicContact CB-CZ3 3.46Å; M42-W142 VanDerWaalsContact CB-CZ3 3.46Å; M42-W142 HydrophobicContact CG-CH2 4.19Å; M42-W142 HydrophobicContact CG-CZ2 4.14Å; M42-W142 HydrophobicContact CG-CZ3 4.4Å; Y43-W142 HydrophobicContact CD1-CH2 4.34Å; Y43-W142 HydrophobicContact CD1-CZ3 4.05Å; Y43-W142 AromaticContact CD2-CH2 3.89Å; Y43-W142 HydrophobicContact CD2-CH2 3.89Å; Y43-W142 HydrophobicContact CD2-CZ3 4.41Å; Y43-W142 HydrophobicContact CE1-CH2 4.16Å; Y43-W142 AromaticContact CE1-CZ3 3.9Å; Y43-W142 HydrophobicContact CE1-CZ3 3.9Å; Y43-W142 AromaticContact CE2-CH2 3.67Å; Y43-W142 HydrophobicContact CE2-CH2 3.67Å; Y43-W142 HydrophobicContact CE2-CZ3 4.26Å; Y43-W142 HydrophobicContact CG-CH2 4.23Å; Y43-W142 HydrophobicContact CG-CZ3 4.31Å; Y43-W142 AromaticContact CZ-CH2 3.83Å; C139-W142 PolarHBondContact O-N 2.97Å; W142-F144 VanDerWaalsContact C-N 3.31Å; W142-F144 PolarHBondContact O-N 3.42Å; W142-K145 HydrophobicContact CD2-CD 4.27Å; W142-K145 HydrophobicContact CE3-CD 3.74Å; W142-K145 HydrophobicContact CZ3-CD 3.94Å; W142-K145 WeakPolarHBondContact O-CB 3.44Å; W142-K145 PolarHBondContact O-N 2.82Å; W142-K145 VanDerWaalsContact O-N 3.09Å; W142-Y146 VanDerWaalsContact O-CD2 3.25Å; W142-Y146 WeakPolarHBondContact O-CD2 3.35Å; W142-Y146 PolarHBondContact O-N 3.02Å
143	F	70.1	Confident	66.5	Low	130 Å²	130	78.8 Å²	78.8	57%	0.57	39%	0.388	S	S	*	.	H	α-helix	trans	-55.9	-46.5	171.8	175.8	-95.2	0	0	0	111.5	C139 S140 K145 Y146 F147	C139-F143 PolarHBondContact O-N 2.59Å; S140-F143 WeakPolarHBondContact O-CB 3.32Å; S140-F143 PolarHBondContact O-N 2.82Å; F143-K145 VanDerWaalsContact C-N 3.31Å; F143-K145 PolarHBondContact O-N 3.42Å; F143-Y146 PolarHBondContact O-N 3.1Å; F143-F147 WeakPolarHBondContact O-CB 3.34Å; F143-F147 PolarHBondContact O-N 3.07Å
144	F	79.8	Confident	69.1	Low	120 Å²	120	75.7 Å²	75.7	53%	0.526	38%	0.377	S	S	.	.	H	α-helix	trans	-62.1	-35.1	175.3	-71.7	-63.9	0	0	0	113.1	S140 F141 W142 A148	S140-F144 WeakPolarHBondContact O-CD2 3.5Å; S140-F144 PolarHBondContact O-N 3.07Å; S140-F144 VanDerWaalsContact O-N 3.16Å; F141-F144 HydrophobicContact CD2-CD2 4.49Å; F141-F144 PolarHBondContact O-N 2.87Å; W142-F144 VanDerWaalsContact C-N 3.31Å; W142-F144 PolarHBondContact O-N 3.42Å; F144-A148 VanDerWaalsContact O-CB 3.27Å; F144-A148 WeakPolarHBondContact O-CB 3.32Å; F144-A148 PolarHBondContact O-N 3.35Å
145	K	84.9	Confident	71.3	Confident	9 Å²	9	72.6 Å²	72.6	4%	0.039	37%	0.366	C	S	.	.	H	α-helix	trans	-64.9	-48.1	174.6	-73.2	173.7	-176.3	173.8	0	112.1	Y43 F100 V121 Q122 F141 W142 F143 F147 A148 L149	Y43-K145 HydrophobicContact CE1-CD 4.25Å; Y43-K145 WeakPolarHBondContact OH-CE 3.28Å; Y43-K145 PolarHBondContact OH-NZ 3.48Å; F100-K145 HydrophobicContact CE2-CB 4.43Å; F100-K145 WeakPolarHBondContact CE2-O 3.11Å; F100-K145 HydrophobicContact CZ-CB 4.04Å; F100-K145 HydrophobicContact CZ-CG 4.33Å; V121-K145 WeakPolarHBondContact O-CE 3.13Å; V121-K145 PolarHBondContact O-NZ 3.29Å; Q122-K145 PolarHBondContact O-NZ 2.69Å; F141-K145 HydrophobicContact CD1-CD 4.49Å; F141-K145 HydrophobicContact CD1-CG 4.47Å; F141-K145 HydrophobicContact CE1-CG 4.44Å; F141-K145 WeakPolarHBondContact O-CG 3.43Å; F141-K145 PolarHBondContact O-N 3.44Å; F141-K145 VanDerWaalsContact O-N 3.08Å; W142-K145 HydrophobicContact CD2-CD 4.27Å; W142-K145 HydrophobicContact CE3-CD 3.74Å; W142-K145 HydrophobicContact CZ3-CD 3.94Å; W142-K145 WeakPolarHBondContact O-CB 3.44Å; W142-K145 PolarHBondContact O-N 2.82Å; W142-K145 VanDerWaalsContact O-N 3.09Å; F143-K145 VanDerWaalsContact C-N 3.31Å; F143-K145 PolarHBondContact O-N 3.42Å; K145-F147 VanDerWaalsContact C-N 3.34Å; K145-A148 PolarHBondContact O-N 3.25Å; K145-L149 PolarHBondContact O-N 3.36Å
146	Y	84.7	Confident	73.8	Confident	63 Å²	63	66.3 Å²	66.3	25%	0.247	34%	0.338	C	S	.	.	H	α-helix	trans	-62	-43.1	175.8	-79.8	-74.9	0	0	0	111.6	M46 L49 W142 F143 A148 L149 I150	M46-Y146 HydrophobicContact CB-CE1 3.91Å; M46-Y146 HydrophobicContact CG-CD1 4.17Å; M46-Y146 HydrophobicContact CG-CE1 3.76Å; L49-Y146 HydrophobicContact CD1-CE1 4.24Å; W142-Y146 VanDerWaalsContact O-CD2 3.25Å; W142-Y146 WeakPolarHBondContact O-CD2 3.35Å; W142-Y146 PolarHBondContact O-N 3.02Å; F143-Y146 PolarHBondContact O-N 3.1Å; Y146-A148 PolarHBondContact O-N 2.91Å; Y146-L149 PolarHBondContact O-N 3.48Å; Y146-I150 WeakPolarHBondContact O-CG1 3.27Å; Y146-I150 PolarHBondContact O-N 3.36Å
147	F	87.6	Confident	76.4	Confident	128 Å²	128	58.5 Å²	58.5	56%	0.561	31%	0.309	S	S	*	.	H	α-helix	trans	-61.4	-43.6	175.7	-175.3	-94.9	0	0	0	112	F143 K145 L149 I150 A151	F143-F147 WeakPolarHBondContact O-CB 3.34Å; F143-F147 PolarHBondContact O-N 3.07Å; K145-F147 VanDerWaalsContact C-N 3.34Å; F147-L149 VanDerWaalsContact C-N 3.33Å; F147-L149 PolarHBondContact O-N 3.5Å; F147-I150 PolarHBondContact O-N 3.41Å; F147-A151 WeakPolarHBondContact O-CB 3.37Å; F147-A151 PolarHBondContact O-N 3.03Å
148	A	89.4	Confident	78.9	Confident	39 Å²	39	65.3 Å²	65.3	32%	0.322	33%	0.332	S	S	.	.	H	α-helix	trans	-61.3	-40.7	176.2	0	0	0	0	0	112	F100 F144 K145 Y146 A151 L152	F100-A148 HydrophobicContact CE2-CB 4.28Å; F144-A148 VanDerWaalsContact O-CB 3.27Å; F144-A148 WeakPolarHBondContact O-CB 3.32Å; F144-A148 PolarHBondContact O-N 3.35Å; K145-A148 PolarHBondContact O-N 3.25Å; Y146-A148 PolarHBondContact O-N 2.91Å; A148-A151 PolarHBondContact O-N 3.15Å; A148-L152 WeakPolarHBondContact O-CB 3.36Å; A148-L152 WeakPolarHBondContact O-CG 3.4Å; A148-L152 PolarHBondContact O-N 3.06Å
149	L	90.8	Very high	80.9	Confident	13 Å²	13	61.8 Å²	61.8	7%	0.068	32%	0.321	C	S	.	.	H	α-helix	trans	-63.6	-43.8	174.5	179.3	62.6	0	0	0	111.8	M46 M97 F100 K145 Y146 F147 L152 A153	M46-L149 HydrophobicContact CE-CD2 4.44Å; M46-L149 HydrophobicContact CG-CD2 3.55Å; M46-L149 HydrophobicContact SD-CD2 3.95Å; M97-L149 HydrophobicContact CG-CD1 4.22Å; F100-L149 HydrophobicContact CB-CD1 3.81Å; F100-L149 HydrophobicContact CD2-CB 4.05Å; F100-L149 HydrophobicContact CD2-CD1 4.43Å; F100-L149 HydrophobicContact CE2-CB 4.35Å; F100-L149 HydrophobicContact CG-CB 4.44Å; F100-L149 HydrophobicContact CG-CD1 4.07Å; K145-L149 PolarHBondContact O-N 3.36Å; Y146-L149 PolarHBondContact O-N 3.48Å; F147-L149 VanDerWaalsContact C-N 3.33Å; F147-L149 PolarHBondContact O-N 3.5Å; L149-L152 PolarHBondContact O-N 3.35Å; L149-A153 WeakPolarHBondContact O-CB 3.45Å; L149-A153 PolarHBondContact O-N 3.49Å
150	I	90.9	Very high	82.3	Confident	105 Å²	105	63.7 Å²	63.7	54%	0.538	33%	0.332	S	S	.	.	H	α-helix	trans	-63.5	-42.5	176.5	-67	165.3	0	0	0	110.7	Y146 F147 A153 V154	Y146-I150 WeakPolarHBondContact O-CG1 3.27Å; Y146-I150 PolarHBondContact O-N 3.36Å; F147-I150 PolarHBondContact O-N 3.41Å; I150-A153 WeakPolarHBondContact O-CB 3.17Å; I150-A153 PolarHBondContact O-N 2.93Å; I150-V154 HydrophobicContact CG2-CG2 4.4Å; I150-V154 WeakPolarHBondContact O-CG2 3.36Å; I150-V154 PolarHBondContact O-N 3.22Å
151	A	92.2	Very high	83.4	Confident	51 Å²	51	67.3 Å²	67.3	42%	0.421	34%	0.341	S	S	.	.	H	α-helix	trans	-62.8	-42.6	177.2	0	0	0	0	0	111.9	F147 A148 A153 V154 G155	F147-A151 WeakPolarHBondContact O-CB 3.37Å; F147-A151 PolarHBondContact O-N 3.03Å; A148-A151 PolarHBondContact O-N 3.15Å; A151-A153 VanDerWaalsContact C-N 3.34Å; A151-V154 PolarHBondContact O-N 2.92Å; A151-G155 PolarHBondContact O-N 3.38Å
152	L	93.3	Very high	83.8	Confident	61 Å²	61	65.1 Å²	65.1	32%	0.319	34%	0.34	S	S	.	.	H	α-helix	trans	-62.9	-40.1	172.4	-76.3	172.1	0	0	0	111.7	A96 F100 A148 L149 G155 A156	A96-L152 HydrophobicContact CB-CB 4.05Å; F100-L152 HydrophobicContact CB-CD1 3.91Å; F100-L152 HydrophobicContact CD2-CD1 4.24Å; A148-L152 WeakPolarHBondContact O-CB 3.36Å; A148-L152 WeakPolarHBondContact O-CG 3.4Å; A148-L152 PolarHBondContact O-N 3.06Å; L149-L152 PolarHBondContact O-N 3.35Å; L152-G155 PolarHBondContact O-N 3.09Å; L152-A156 WeakPolarHBondContact O-CB 3.42Å; L152-A156 PolarHBondContact O-N 2.79Å
153	A	91.8	Very high	84.3	Confident	12 Å²	12	69.9 Å²	69.9	10%	0.099	37%	0.368	C	S	.	.	H	α-helix	trans	-61.3	-53.4	176.1	0	0	0	0	0	110.7	M93 A96 L149 I150 A151 G155 A156 F157	M93-A153 HydrophobicContact SD-CB 3.96Å; A96-A153 HydrophobicContact CB-CB 3.96Å; L149-A153 WeakPolarHBondContact O-CB 3.45Å; L149-A153 PolarHBondContact O-N 3.49Å; I150-A153 WeakPolarHBondContact O-CB 3.17Å; I150-A153 PolarHBondContact O-N 2.93Å; A151-A153 VanDerWaalsContact C-N 3.34Å; A153-G155 VanDerWaalsContact C-N 3.29Å; A153-G155 PolarHBondContact O-N 3.38Å; A153-A156 WeakPolarHBondContact O-CB 3.11Å; A153-A156 PolarHBondContact O-N 3.24Å; A153-A156 VanDerWaalsContact O-N 3.09Å; A153-F157 WeakPolarHBondContact O-CD2 3.18Å; A153-F157 PolarHBondContact O-N 2.84Å; A153-F157 VanDerWaalsContact O-N 3.1Å
154	V	90.8	Very high	84.8	Confident	76 Å²	76	66.5 Å²	66.5	46%	0.461	35%	0.353	S	S	.	.	H	α-helix	trans	-56.6	-44.3	176.5	173.6	0	0	0	0	110.9	I150 A151 A156 F157 Y158	I150-V154 HydrophobicContact CG2-CG2 4.4Å; I150-V154 WeakPolarHBondContact O-CG2 3.36Å; I150-V154 PolarHBondContact O-N 3.22Å; A151-V154 PolarHBondContact O-N 2.92Å; V154-A156 PolarHBondContact O-N 3.35Å; V154-F157 WeakPolarHBondContact O-CB 3.39Å; V154-F157 PolarHBondContact O-N 3.21Å; V154-Y158 HydrophobicContact CG1-CE2 3.88Å; V154-Y158 WeakPolarHBondContact O-CD2 3.5Å
155	G	90	Very high	84.6	Confident	40 Å²	40	61.4 Å²	61.4	41%	0.412	33%	0.333	S	S	.	.	H	α-helix	trans	-60.4	-41.6	175.4	0	0	0	0	0	113.4	A151 L152 A153 F157 Y158	A151-G155 PolarHBondContact O-N 3.38Å; L152-G155 PolarHBondContact O-N 3.09Å; A153-G155 VanDerWaalsContact C-N 3.29Å; A153-G155 PolarHBondContact O-N 3.38Å; G155-F157 VanDerWaalsContact C-N 3.25Å; G155-F157 PolarHBondContact O-N 3.21Å; G155-Y158 PolarHBondContact O-N 3.18Å; G155-Y158 VanDerWaalsContact O-N 3.16Å
156	A	89.7	Confident	84.3	Confident	2 Å²	2	63 Å²	63	2%	0.017	34%	0.341	C	S	.	.	H	α-helix	trans	-64.8	-29.4	177.3	0	0	0	0	0	112.7	R92 F95 A96 L152 A153 V154 Y158 I159	R92-A156 HydrophobicContact CB-CB 4.32Å; R92-A156 WeakPolarHBondContact CD-O 3.39Å; R92-A156 VanDerWaalsContact O-CB 3.3Å; R92-A156 WeakPolarHBondContact O-CB 3.47Å; F95-A156 HydrophobicContact CD1-CB 3.83Å; A96-A156 HydrophobicContact CB-CB 4.21Å; L152-A156 WeakPolarHBondContact O-CB 3.42Å; L152-A156 PolarHBondContact O-N 2.79Å; A153-A156 WeakPolarHBondContact O-CB 3.11Å; A153-A156 PolarHBondContact O-N 3.24Å; A153-A156 VanDerWaalsContact O-N 3.09Å; V154-A156 PolarHBondContact O-N 3.35Å; A156-Y158 VanDerWaalsContact C-N 3.25Å; A156-Y158 PolarHBondContact O-N 2.79Å; A156-I159 HydrophobicContact CB-CD1 4.43Å; A156-I159 WeakPolarHBondContact O-CB 3.37Å; A156-I159 WeakPolarHBondContact O-CG1 3.41Å; A156-I159 PolarHBondContact O-N 3.06Å
157	F	86.5	Confident	84.4	Confident	29 Å²	29	62.5 Å²	62.5	13%	0.127	35%	0.35	C	S	.	.	H	α-helix	trans	-66	-23.8	174.8	-86.3	-81.3	0	0	0	114.1	M57 W71 F72 A153 V154 G155 I159	M57-F157 HydrophobicContact CE-CE1 4.45Å; M57-F157 HydrophobicContact CE-CE2 3.78Å; M57-F157 HydrophobicContact CE-CZ 3.37Å; M57-F157 HydrophobicContact SD-CZ 3.82Å; W71-F157 HydrophobicContact CH2-CB 3.86Å; W71-F157 HydrophobicContact CH2-CD1 4.16Å; W71-F157 HydrophobicContact CH2-CG 4.26Å; W71-F157 HydrophobicContact CZ3-CB 3.91Å; F72-F157 HydrophobicContact CD2-CD1 4.03Å; F72-F157 HydrophobicContact CD2-CE1 4.42Å; F72-F157 AromaticContact CE2-CD1 3.67Å; F72-F157 HydrophobicContact CE2-CD1 3.67Å; F72-F157 AromaticContact CE2-CE1 3.74Å; F72-F157 HydrophobicContact CE2-CE1 3.74Å; A153-F157 WeakPolarHBondContact O-CD2 3.18Å; A153-F157 PolarHBondContact O-N 2.84Å; A153-F157 VanDerWaalsContact O-N 3.1Å; V154-F157 WeakPolarHBondContact O-CB 3.39Å; V154-F157 PolarHBondContact O-N 3.21Å; G155-F157 VanDerWaalsContact C-N 3.25Å; G155-F157 PolarHBondContact O-N 3.21Å; F157-I159 VanDerWaalsContact C-N 3.3Å; F157-I159 PolarHBondContact O-N 3.05Å
158	Y	84.8	Confident	84.4	Confident	172 Å²	172	57.4 Å²	57.4	68%	0.675	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.4	-4.9	175.9	-71.8	-81.7	0	0	0	114	V154 G155 A156 P160	V154-Y158 HydrophobicContact CG1-CE2 3.88Å; V154-Y158 WeakPolarHBondContact O-CD2 3.5Å; G155-Y158 PolarHBondContact O-N 3.18Å; G155-Y158 VanDerWaalsContact O-N 3.16Å; A156-Y158 VanDerWaalsContact C-N 3.25Å; A156-Y158 PolarHBondContact O-N 2.79Å; Y158-P160 WeakPolarHBondContact O-CD 3.26Å
159	I	82.5	Confident	84.2	Confident	40 Å²	40	55.5 Å²	55.5	21%	0.205	31%	0.311	C	S	.	.	P	Polyproline II helix	trans	-72.8	117.1	-179.9	-58.1	173.6	0	0	0	109.3	R92 F95 A156 F157 F164	R92-I159 PolarHBondContact NE-O 3.09Å; R92-I159 PolarHBondContact NH2-O 3.02Å; F95-I159 HydrophobicContact CD1-CD1 4.12Å; F95-I159 HydrophobicContact CE1-CD1 3.9Å; A156-I159 HydrophobicContact CB-CD1 4.43Å; A156-I159 WeakPolarHBondContact O-CB 3.37Å; A156-I159 WeakPolarHBondContact O-CG1 3.41Å; A156-I159 PolarHBondContact O-N 3.06Å; F157-I159 VanDerWaalsContact C-N 3.3Å; F157-I159 PolarHBondContact O-N 3.05Å; I159-F164 HydrophobicContact CD1-CE1 4.22Å; I159-F164 HydrophobicContact CD1-CE2 4.29Å; I159-F164 HydrophobicContact CD1-CZ 3.93Å; I159-F164 HydrophobicContact CG2-CB 4.23Å; I159-F164 HydrophobicContact CG2-CD1 3.67Å; I159-F164 HydrophobicContact CG2-CD2 4.29Å; I159-F164 HydrophobicContact CG2-CE1 4.07Å; I159-F164 HydrophobicContact CG2-CG 3.79Å
160	P	72.3	Confident	83.9	Confident	103 Å²	103	60.2 Å²	60.2	67%	0.669	33%	0.329	S	S	*	.	P	Polyproline II helix	trans	-67.6	154.9	-178.7	29.2	-34.8	0	0	0	111.4	Y158	Y158-P160 WeakPolarHBondContact O-CD 3.26Å
161	Y	68.5	Low	83.9	Confident	109 Å²	109	59 Å²	59	43%	0.427	32%	0.323	S	S	.	.	S	Bend	trans	-67.4	141.1	173.8	178.6	-93.2	0	0	0	110.9	Q88	Q88-Y161 VanDerWaalsContact NE2-CD2 3.31Å
162	G	71.7	Confident	83.8	Confident	28 Å²	28	56.6 Å²	56.6	29%	0.289	30%	0.303	S	S	.	.	S	Bend	trans	159	-146.9	179.3	0	0	0	0	0	110.6	F164 S165	G162-F164 PolarHBondContact O-N 3.21Å; G162-S165 PolarHBondContact O-N 2.97Å; G162-S165 VanDerWaalsContact O-N 3.11Å
163	D	77.4	Confident	83.4	Confident	138 Å²	138	54.9 Å²	54.9	74%	0.738	29%	0.294	S	S	*	.	H	α-helix	trans	-56	-24.8	-176.5	-57.3	-29	0	0	0	114.3	S165 I166 A167	D163-S165 VanDerWaalsContact C-N 3.33Å; D163-S165 PolarHBondContact O-N 3.37Å; D163-I166 PolarHBondContact O-N 3.43Å; D163-A167 WeakPolarHBondContact O-CB 3.33Å; D163-A167 PolarHBondContact O-N 3.02Å
164	F	81.6	Confident	83.2	Confident	58 Å²	58	57.8 Å²	57.8	25%	0.254	31%	0.312	S	S	.	.	H	α-helix	trans	-56.8	-44.3	176.4	175	-99.2	0	0	0	112.3	F95 I159 G162 I166 A167 W168	F95-F164 HydrophobicContact CB-CZ 4.37Å; F95-F164 HydrophobicContact CD1-CZ 4.26Å; F95-F164 HydrophobicContact CD2-CE2 4.08Å; F95-F164 AromaticContact CD2-CZ 3.61Å; F95-F164 HydrophobicContact CD2-CZ 3.61Å; F95-F164 HydrophobicContact CE1-CZ 4.48Å; F95-F164 AromaticContact CE2-CE2 3.88Å; F95-F164 HydrophobicContact CE2-CE2 3.88Å; F95-F164 AromaticContact CE2-CZ 3.87Å; F95-F164 HydrophobicContact CE2-CZ 3.87Å; F95-F164 AromaticContact CG-CZ 3.82Å; F95-F164 HydrophobicContact CG-CZ 3.82Å; F95-F164 HydrophobicContact CZ-CE2 4.27Å; F95-F164 HydrophobicContact CZ-CZ 4.3Å; I159-F164 HydrophobicContact CD1-CE1 4.22Å; I159-F164 HydrophobicContact CD1-CE2 4.29Å; I159-F164 HydrophobicContact CD1-CZ 3.93Å; I159-F164 HydrophobicContact CG2-CB 4.23Å; I159-F164 HydrophobicContact CG2-CD1 3.67Å; I159-F164 HydrophobicContact CG2-CD2 4.29Å; I159-F164 HydrophobicContact CG2-CE1 4.07Å; I159-F164 HydrophobicContact CG2-CG 3.79Å; G162-F164 PolarHBondContact O-N 3.21Å; F164-I166 VanDerWaalsContact C-N 3.32Å; F164-I166 PolarHBondContact O-N 3.14Å; F164-A167 PolarHBondContact O-N 2.88Å; F164-W168 HydrophobicContact CE1-CB 4.44Å; F164-W168 HydrophobicContact CE1-CG 4.5Å; F164-W168 HydrophobicContact CZ-CB 4.39Å; F164-W168 HydrophobicContact CZ-CG 4.26Å; F164-W168 WeakPolarHBondContact O-CB 3.44Å; F164-W168 PolarHBondContact O-N 3.27Å
165	S	75.5	Confident	83.2	Confident	14 Å²	14	54.4 Å²	54.4	10%	0.098	29%	0.292	C	S	.	.	H	α-helix	trans	-65	-38.5	-177.7	-59	0	0	0	0	111.8	G162 D163 L169	G162-S165 PolarHBondContact O-N 2.97Å; G162-S165 VanDerWaalsContact O-N 3.11Å; D163-S165 VanDerWaalsContact C-N 3.33Å; D163-S165 PolarHBondContact O-N 3.37Å; S165-L169 WeakPolarHBondContact O-CB 3.45Å; S165-L169 PolarHBondContact O-N 3.05Å
166	I	78.5	Confident	83.1	Confident	43 Å²	43	52.5 Å²	52.5	22%	0.221	27%	0.273	C	S	.	.	H	α-helix	trans	-69.3	-49.4	178.9	-57.1	170.7	0	0	0	109.8	D163 F164 W168 L169 Y170 P422 D423	D163-I166 PolarHBondContact O-N 3.43Å; F164-I166 VanDerWaalsContact C-N 3.32Å; F164-I166 PolarHBondContact O-N 3.14Å; I166-W168 VanDerWaalsContact C-N 3.3Å; I166-W168 PolarHBondContact O-N 3.2Å; I166-L169 WeakPolarHBondContact O-CB 3.34Å; I166-L169 PolarHBondContact O-N 3.49Å; I166-Y170 HydrophobicContact CG2-CD2 4.14Å; I166-Y170 HydrophobicContact CG2-CE2 3.7Å; I166-Y170 WeakPolarHBondContact O-CD2 3.33Å; I166-Y170 PolarHBondContact O-N 3.23Å; I166-P422 HydrophobicContact CG1-CG 4.13Å; I166-D423 WeakPolarHBondContact CD1-OD1 3.28Å; I166-D423 VanDerWaalsContact CG1-OD1 3.23Å; I166-D423 WeakPolarHBondContact CG1-OD1 3.38Å
167	A	85.7	Confident	82.9	Confident	51 Å²	51	56 Å²	56	42%	0.421	29%	0.288	S	S	.	.	H	α-helix	trans	-60.3	-43	177.6	0	0	0	0	0	111.6	D163 F164 L169 Y170 I171	D163-A167 WeakPolarHBondContact O-CB 3.33Å; D163-A167 PolarHBondContact O-N 3.02Å; F164-A167 PolarHBondContact O-N 2.88Å; A167-L169 VanDerWaalsContact C-N 3.35Å; A167-L169 PolarHBondContact O-N 2.9Å; A167-Y170 PolarHBondContact O-N 2.97Å; A167-I171 WeakPolarHBondContact O-CG1 3.35Å; A167-I171 PolarHBondContact O-N 2.7Å; A167-I171 VanDerWaalsContact O-N 3.16Å
168	W	88.9	Confident	83	Confident	21 Å²	21	57.6 Å²	57.6	8%	0.08	30%	0.297	C	S	.	.	H	α-helix	trans	-69	-32.1	-179.4	-165.8	-129.8	0	0	0	112.7	Y91 F95 A98 F164 I166 I171 G172 L410 M413	Y91-W168 AromaticContact CD1-CD1 3.67Å; Y91-W168 PolarHBondContact O-NE1 3.47Å; F95-W168 HydrophobicContact CB-CZ2 4.04Å; F95-W168 AromaticContact CD2-CD2 3.88Å; F95-W168 HydrophobicContact CD2-CD2 3.88Å; F95-W168 AromaticContact CD2-CE2 3.65Å; F95-W168 AromaticContact CD2-CE3 3.96Å; F95-W168 HydrophobicContact CD2-CE3 3.96Å; F95-W168 AromaticContact CD2-CH2 3.72Å; F95-W168 HydrophobicContact CD2-CH2 3.72Å; F95-W168 AromaticContact CD2-CZ2 3.63Å; F95-W168 HydrophobicContact CD2-CZ2 3.63Å; F95-W168 AromaticContact CD2-CZ3 3.87Å; F95-W168 HydrophobicContact CD2-CZ3 3.87Å; F95-W168 HydrophobicContact CE2-CE3 4.35Å; F95-W168 HydrophobicContact CE2-CH2 4.3Å; F95-W168 HydrophobicContact CE2-CZ3 4.15Å; F95-W168 HydrophobicContact CG-CZ2 4.3Å; A98-W168 HydrophobicContact CB-CH2 3.89Å; A98-W168 HydrophobicContact CB-CZ2 3.8Å; F164-W168 HydrophobicContact CE1-CB 4.44Å; F164-W168 HydrophobicContact CE1-CG 4.5Å; F164-W168 HydrophobicContact CZ-CB 4.39Å; F164-W168 HydrophobicContact CZ-CG 4.26Å; F164-W168 WeakPolarHBondContact O-CB 3.44Å; F164-W168 PolarHBondContact O-N 3.27Å; I166-W168 VanDerWaalsContact C-N 3.3Å; I166-W168 PolarHBondContact O-N 3.2Å; W168-I171 HydrophobicContact CE3-CB 4.15Å; W168-I171 HydrophobicContact CE3-CD1 3.92Å; W168-I171 HydrophobicContact CE3-CG2 4.11Å; W168-I171 HydrophobicContact CH2-CG2 4.4Å; W168-I171 HydrophobicContact CZ3-CB 4.36Å; W168-I171 HydrophobicContact CZ3-CD1 4.19Å; W168-I171 HydrophobicContact CZ3-CG2 3.81Å; W168-G172 PolarHBondContact O-N 2.9Å; W168-L410 HydrophobicContact CH2-CD2 3.73Å; W168-L410 HydrophobicContact CZ2-CD2 3.48Å; W168-L410 VanDerWaalsContact CZ2-CD2 3.48Å; W168-M413 VanDerWaalsContact CD1-SD 3.55Å; W168-M413 HydrophobicContact CG-SD 4.48Å; W168-M413 PolarHBondContact NE1-SD 2.8Å
169	L	84.5	Confident	83.2	Confident	0 Å²	0	49.5 Å²	49.5	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-58.2	-50.3	168.8	172.2	80.5	0	0	0	111.8	Y91 S165 I166 A167 I171 G172 M173 M414 Y420 R421	Y91-L169 HydrophobicContact CE1-CB 4.46Å; Y91-L169 WeakPolarHBondContact OH-CD1 3.46Å; S165-L169 WeakPolarHBondContact O-CB 3.45Å; S165-L169 PolarHBondContact O-N 3.05Å; I166-L169 WeakPolarHBondContact O-CB 3.34Å; I166-L169 PolarHBondContact O-N 3.49Å; A167-L169 VanDerWaalsContact C-N 3.35Å; A167-L169 PolarHBondContact O-N 2.9Å; L169-I171 VanDerWaalsContact C-N 3.33Å; L169-I171 PolarHBondContact O-N 3.28Å; L169-G172 CarbonylContact O-C 3.49Å; L169-G172 WeakPolarHBondContact O-CA 3.3Å; L169-G172 PolarHBondContact O-N 3.45Å; L169-G172 VanDerWaalsContact O-N 3.13Å; L169-M173 HydrophobicContact CD1-CG 4.44Å; L169-M173 HydrophobicContact CD2-CE 4.32Å; L169-M173 HydrophobicContact CG-CE 4.15Å; L169-M173 HydrophobicContact CG-CG 4.47Å; L169-M173 HydrophobicContact CG-SD 4.48Å; L169-M173 WeakPolarHBondContact O-CG 3.44Å; L169-M173 PolarHBondContact O-N 3.45Å; L169-M414 HydrophobicContact CD1-CE 3.54Å; L169-M414 HydrophobicContact CD1-SD 4.14Å; L169-Y420 WeakPolarHBondContact CD1-O 3.45Å; L169-R421 HydrophobicContact CD2-CG 3.92Å
170	Y	85.2	Confident	83.5	Confident	111 Å²	111	47.9 Å²	47.9	44%	0.435	26%	0.257	S	S	.	.	H	α-helix	trans	-62.7	-41.1	-178.6	-75.1	-73.1	0	0	0	112.1	I166 A167 G172 M173 C174	I166-Y170 HydrophobicContact CG2-CD2 4.14Å; I166-Y170 HydrophobicContact CG2-CE2 3.7Å; I166-Y170 WeakPolarHBondContact O-CD2 3.33Å; I166-Y170 PolarHBondContact O-N 3.23Å; A167-Y170 PolarHBondContact O-N 2.97Å; Y170-G172 VanDerWaalsContact C-N 3.32Å; Y170-M173 HydrophobicContact CD1-CE 3.22Å; Y170-M173 HydrophobicContact CE1-CE 3.58Å; Y170-M173 HydrophobicContact CG-CE 3.95Å; Y170-M173 PolarHBondContact O-N 3.33Å; Y170-C174 PolarHBondContact O-N 3.3Å; Y170-C174 VanDerWaalsContact O-N 3.08Å
171	I	90.3	Very high	84.1	Confident	81 Å²	81	44.6 Å²	44.6	42%	0.415	24%	0.235	S	C	.	.	H	α-helix	trans	-62	-43.6	173.1	-65.5	168.1	0	0	0	110.2	A167 W168 L169 C174 G175 L410	A167-I171 WeakPolarHBondContact O-CG1 3.35Å; A167-I171 PolarHBondContact O-N 2.7Å; A167-I171 VanDerWaalsContact O-N 3.16Å; W168-I171 HydrophobicContact CE3-CB 4.15Å; W168-I171 HydrophobicContact CE3-CD1 3.92Å; W168-I171 HydrophobicContact CE3-CG2 4.11Å; W168-I171 HydrophobicContact CH2-CG2 4.4Å; W168-I171 HydrophobicContact CZ3-CB 4.36Å; W168-I171 HydrophobicContact CZ3-CD1 4.19Å; W168-I171 HydrophobicContact CZ3-CG2 3.81Å; L169-I171 VanDerWaalsContact C-N 3.33Å; L169-I171 PolarHBondContact O-N 3.28Å; I171-C174 PolarHBondContact O-N 2.89Å; I171-G175 PolarHBondContact O-N 2.91Å; I171-L410 HydrophobicContact CG2-CD1 4.27Å
172	G	90	Very high	84.9	Confident	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-57.1	-48.9	174.6	0	0	0	0	0	113.2	W168 L169 Y170 G175 A176 M414	W168-G172 PolarHBondContact O-N 2.9Å; L169-G172 CarbonylContact O-C 3.49Å; L169-G172 WeakPolarHBondContact O-CA 3.3Å; L169-G172 PolarHBondContact O-N 3.45Å; L169-G172 VanDerWaalsContact O-N 3.13Å; Y170-G172 VanDerWaalsContact C-N 3.32Å; G172-G175 PolarHBondContact O-N 3.33Å; G172-A176 WeakPolarHBondContact O-CB 3.16Å; G172-A176 PolarHBondContact O-N 3.18Å; G172-M414 VanDerWaalsContact C-CG 3.44Å; G172-M414 WeakPolarHBondContact O-CG 3.43Å
173	M	84.6	Confident	85.7	Confident	25 Å²	25	39.8 Å²	39.8	12%	0.123	21%	0.21	C	C	.	.	H	α-helix	trans	-61.1	-45.9	178.6	-72.9	-170.5	-63.4	0	0	111.9	L169 Y170 F177 M414 W419	L169-M173 HydrophobicContact CD1-CG 4.44Å; L169-M173 HydrophobicContact CD2-CE 4.32Å; L169-M173 HydrophobicContact CG-CE 4.15Å; L169-M173 HydrophobicContact CG-CG 4.47Å; L169-M173 HydrophobicContact CG-SD 4.48Å; L169-M173 WeakPolarHBondContact O-CG 3.44Å; L169-M173 PolarHBondContact O-N 3.45Å; Y170-M173 HydrophobicContact CD1-CE 3.22Å; Y170-M173 HydrophobicContact CE1-CE 3.58Å; Y170-M173 HydrophobicContact CG-CE 3.95Å; Y170-M173 PolarHBondContact O-N 3.33Å; M173-F177 WeakPolarHBondContact O-CB 3.45Å; M173-F177 PolarHBondContact O-N 2.93Å; M173-M414 HydrophobicContact CG-CE 3.77Å; M173-M414 HydrophobicContact CG-SD 4.42Å; M173-W419 HydrophobicContact CB-CZ3 4.1Å; M173-W419 HydrophobicContact CG-CE3 3.99Å; M173-W419 HydrophobicContact CG-CZ3 3.91Å
174	C	87.6	Confident	86.1	Confident	73 Å²	73	33.2 Å²	33.2	49%	0.493	18%	0.175	S	C	.	.	H	α-helix	trans	-63.8	-47.9	177.8	-175.5	0	0	0	0	111.3	Y170 I171 A176 F177 I178	Y170-C174 PolarHBondContact O-N 3.3Å; Y170-C174 VanDerWaalsContact O-N 3.08Å; I171-C174 PolarHBondContact O-N 2.89Å; C174-A176 PolarHBondContact O-N 3.39Å; C174-F177 PolarHBondContact O-N 3.49Å; C174-I178 WeakPolarHBondContact O-CG1 3.47Å; C174-I178 PolarHBondContact O-N 3.37Å
175	G	90.6	Very high	86.2	Confident	4 Å²	4	33.9 Å²	33.9	4%	0.041	18%	0.18	C	C	.	.	H	α-helix	trans	-63.2	-40.5	178.1	0	0	0	0	0	113.1	I171 G172 I178 F179	I171-G175 PolarHBondContact O-N 2.91Å; G172-G175 PolarHBondContact O-N 3.33Å; G175-I178 PolarHBondContact O-N 2.64Å; G175-F179 WeakPolarHBondContact O-CB 3.5Å; G175-F179 PolarHBondContact O-N 2.78Å
176	A	88.7	Confident	86.6	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-65.6	-39.9	175.8	0	0	0	0	0	111.9	G172 C174 F179 I180 Y411 M414 W419	G172-A176 WeakPolarHBondContact O-CB 3.16Å; G172-A176 PolarHBondContact O-N 3.18Å; C174-A176 PolarHBondContact O-N 3.39Å; A176-F179 PolarHBondContact O-N 2.95Å; A176-I180 WeakPolarHBondContact O-CB 3.25Å; A176-I180 WeakPolarHBondContact O-CG1 3.42Å; A176-I180 PolarHBondContact O-N 3.32Å; A176-Y411 HydrophobicContact CB-CD2 4.31Å; A176-M414 HydrophobicContact CB-CB 3.94Å; A176-M414 HydrophobicContact CB-CG 3.75Å; A176-W419 HydrophobicContact CB-CH2 3.5Å; A176-W419 HydrophobicContact CB-CZ2 3.79Å; A176-W419 HydrophobicContact CB-CZ3 4.41Å
177	F	84.9	Confident	87	Confident	75 Å²	75	32.8 Å²	32.8	33%	0.329	17%	0.173	S	C	.	.	H	α-helix	trans	-60.9	-47.7	173.5	172.8	-110.2	0	0	0	111.8	M173 C174 F179 I180 V181 V439	M173-F177 WeakPolarHBondContact O-CB 3.45Å; M173-F177 PolarHBondContact O-N 2.93Å; C174-F177 PolarHBondContact O-N 3.49Å; F177-F179 VanDerWaalsContact C-N 3.31Å; F177-F179 PolarHBondContact O-N 2.97Å; F177-I180 PolarHBondContact O-N 2.9Å; F177-V181 HydrophobicContact CE2-CG2 4.33Å; F177-V181 HydrophobicContact CZ-CG2 4.29Å; F177-V181 PolarHBondContact O-N 3.28Å; F177-V439 HydrophobicContact CB-CG1 4.25Å; F177-V439 HydrophobicContact CD2-CG1 3.98Å
178	I	88.6	Confident	87	Confident	64 Å²	64	30.7 Å²	30.7	33%	0.328	16%	0.155	S	C	.	.	H	α-helix	trans	-62.1	-42.4	177.3	-61	163.7	0	0	0	110.3	C174 G175 V181 L182 L407	C174-I178 WeakPolarHBondContact O-CG1 3.47Å; C174-I178 PolarHBondContact O-N 3.37Å; G175-I178 PolarHBondContact O-N 2.64Å; I178-V181 PolarHBondContact O-N 3.03Å; I178-L182 HydrophobicContact CG2-CD1 4.41Å; I178-L182 WeakPolarHBondContact O-CG 3.48Å; I178-L182 PolarHBondContact O-N 3.24Å; I178-L407 HydrophobicContact CB-CD1 4.27Å; I178-L407 HydrophobicContact CB-CD2 4.33Å; I178-L407 HydrophobicContact CG2-CD1 3.57Å; I178-L407 HydrophobicContact CG2-CD2 4.4Å
179	F	90.6	Very high	86.7	Confident	2 Å²	2	31.5 Å²	31.5	1%	0.009	16%	0.162	C	C	.	.	H	α-helix	trans	-64.1	-40.5	176.9	-169.7	-95.1	0	0	0	112.3	G175 A176 F177 V181 L182 Q183 W341 I404 L407 A408 Y411	G175-F179 WeakPolarHBondContact O-CB 3.5Å; G175-F179 PolarHBondContact O-N 2.78Å; A176-F179 PolarHBondContact O-N 2.95Å; F177-F179 VanDerWaalsContact C-N 3.31Å; F177-F179 PolarHBondContact O-N 2.97Å; F179-V181 VanDerWaalsContact C-N 3.3Å; F179-V181 PolarHBondContact O-N 3.28Å; F179-L182 PolarHBondContact O-N 3.29Å; F179-Q183 HydrophobicContact CD1-CB 4.48Å; F179-Q183 HydrophobicContact CE1-CB 4.24Å; F179-Q183 VanDerWaalsContact O-CB 3.26Å; F179-Q183 WeakPolarHBondContact O-CB 3.47Å; F179-Q183 PolarHBondContact O-N 3.45Å; F179-W341 AromaticContact CE1-CD1 3.4Å; F179-W341 VanDerWaalsContact CE1-CD1 3.4Å; F179-W341 HydrophobicContact CE1-CG 4.47Å; F179-W341 AromaticContact CZ-CD1 3.65Å; F179-W341 AromaticContact CZ-NE1 3.94Å; F179-I404 HydrophobicContact CE2-CG2 4.21Å; F179-L407 HydrophobicContact CB-CB 4.07Å; F179-L407 HydrophobicContact CD2-CB 3.84Å; F179-L407 HydrophobicContact CG-CB 4.42Å; F179-A408 VanDerWaalsContact CD2-CA 3.46Å; F179-A408 HydrophobicContact CD2-CB 3.96Å; F179-A408 VanDerWaalsContact CD2-N 3.29Å; F179-A408 VanDerWaalsContact CE2-CA 3.44Å; F179-A408 HydrophobicContact CE2-CB 3.39Å; F179-A408 HydrophobicContact CZ-CB 3.8Å; F179-Y411 HydrophobicContact CD1-CD1 4.01Å; F179-Y411 AromaticContact CD1-CD2 3.94Å; F179-Y411 HydrophobicContact CD1-CD2 3.94Å; F179-Y411 AromaticContact CD1-CG 3.53Å; F179-Y411 HydrophobicContact CD1-CG 3.53Å; F179-Y411 HydrophobicContact CE1-CD1 4.17Å; F179-Y411 HydrophobicContact CE1-CG 4.16Å; F179-Y411 HydrophobicContact CG-CG 4.33Å
180	I	87.4	Confident	86.7	Confident	6 Å²	6	34.7 Å²	34.7	3%	0.031	18%	0.175	C	C	.	.	H	α-helix	trans	-57.6	-46.8	174.1	-71.5	162.7	0	0	0	109.1	A176 F177 L182 Q183 L184 Y411 W419 V439 S443	A176-I180 WeakPolarHBondContact O-CB 3.25Å; A176-I180 WeakPolarHBondContact O-CG1 3.42Å; A176-I180 PolarHBondContact O-N 3.32Å; F177-I180 PolarHBondContact O-N 2.9Å; I180-L182 PolarHBondContact O-N 3.44Å; I180-Q183 CarbonylContact O-C 3.6Å; I180-Q183 WeakPolarHBondContact O-CA 3.37Å; I180-Q183 WeakPolarHBondContact O-CB 3.18Å; I180-Q183 PolarHBondContact O-N 3.29Å; I180-Q183 VanDerWaalsContact O-N 3.13Å; I180-L184 HydrophobicContact CG2-CG 4.45Å; I180-L184 VanDerWaalsContact O-CG 3.29Å; I180-L184 WeakPolarHBondContact O-CG 3.37Å; I180-L184 PolarHBondContact O-N 2.83Å; I180-Y411 HydrophobicContact CD1-CD2 4.34Å; I180-Y411 HydrophobicContact CD1-CE2 4.08Å; I180-Y411 HydrophobicContact CG1-CD2 3.82Å; I180-Y411 HydrophobicContact CG1-CE2 3.6Å; I180-W419 HydrophobicContact CD1-CH2 4.38Å; I180-W419 HydrophobicContact CD1-CZ2 4.08Å; I180-V439 HydrophobicContact CD1-CG1 4.12Å; I180-S443 VanDerWaalsContact CG2-OG 3.31Å; I180-S443 WeakPolarHBondContact CG2-OG 3.41Å
181	V	85.3	Confident	86.9	Confident	34 Å²	34	29.4 Å²	29.4	21%	0.206	16%	0.155	C	C	.	.	H	α-helix	trans	-60	-44.8	177	176.7	0	0	0	0	112.2	F177 I178 F179 Q183 L184 I185 V446	F177-V181 HydrophobicContact CE2-CG2 4.33Å; F177-V181 HydrophobicContact CZ-CG2 4.29Å; F177-V181 PolarHBondContact O-N 3.28Å; I178-V181 PolarHBondContact O-N 3.03Å; F179-V181 VanDerWaalsContact C-N 3.3Å; F179-V181 PolarHBondContact O-N 3.28Å; V181-Q183 VanDerWaalsContact C-N 3.31Å; V181-Q183 PolarHBondContact O-N 3.35Å; V181-L184 WeakPolarHBondContact O-CB 3.34Å; V181-L184 PolarHBondContact O-N 3.23Å; V181-I185 HydrophobicContact CG1-CD1 4.36Å; V181-I185 WeakPolarHBondContact O-CG1 3.34Å; V181-I185 PolarHBondContact O-N 3.15Å; V181-I185 VanDerWaalsContact O-N 3.09Å; V181-V446 HydrophobicContact CG1-CG1 4.28Å; V181-V446 HydrophobicContact CG2-CG1 4.48Å
182	L	85.4	Confident	86.5	Confident	35 Å²	35	26.1 Å²	26.1	18%	0.183	14%	0.138	C	C	.	.	H	α-helix	trans	-61.8	-40.1	174.6	-70	173.2	0	0	0	112	I178 F179 I180 L184 I185 L186 I404 L407	I178-L182 HydrophobicContact CG2-CD1 4.41Å; I178-L182 WeakPolarHBondContact O-CG 3.48Å; I178-L182 PolarHBondContact O-N 3.24Å; F179-L182 PolarHBondContact O-N 3.29Å; I180-L182 PolarHBondContact O-N 3.44Å; L182-L184 VanDerWaalsContact C-N 3.33Å; L182-L184 PolarHBondContact O-N 3.42Å; L182-I185 PolarHBondContact O-N 3.28Å; L182-L186 VanDerWaalsContact O-CG 3.31Å; L182-L186 WeakPolarHBondContact O-CG 3.45Å; L182-L186 PolarHBondContact O-N 3.47Å; L182-I404 HydrophobicContact CD1-CG1 4.42Å; L182-L407 HydrophobicContact CD1-CD1 3.55Å
183	Q	88.8	Confident	86.2	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-62.4	-40.1	175.6	-174.7	-179.8	-61.8	0	0	111.1	F179 I180 V181 L186 L187 Y286 I344	F179-Q183 HydrophobicContact CD1-CB 4.48Å; F179-Q183 HydrophobicContact CE1-CB 4.24Å; F179-Q183 VanDerWaalsContact O-CB 3.26Å; F179-Q183 WeakPolarHBondContact O-CB 3.47Å; F179-Q183 PolarHBondContact O-N 3.45Å; I180-Q183 CarbonylContact O-C 3.6Å; I180-Q183 WeakPolarHBondContact O-CA 3.37Å; I180-Q183 WeakPolarHBondContact O-CB 3.18Å; I180-Q183 PolarHBondContact O-N 3.29Å; I180-Q183 VanDerWaalsContact O-N 3.13Å; V181-Q183 VanDerWaalsContact C-N 3.31Å; V181-Q183 PolarHBondContact O-N 3.35Å; Q183-L186 PolarHBondContact O-N 3.49Å; Q183-L187 VanDerWaalsContact O-CB 3.24Å; Q183-L187 WeakPolarHBondContact O-CB 3.39Å; Q183-L187 PolarHBondContact O-N 3.31Å; Q183-Y286 PolarHBondContact NE2-OH 2.87Å; Q183-I344 HydrophobicContact CG-CB 4.39Å; Q183-I344 HydrophobicContact CG-CG1 3.97Å; Q183-I344 HydrophobicContact CG-CG2 4.2Å
184	L	85.9	Confident	86.3	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-60.2	-47.9	174.2	-61.4	169.6	0	0	0	110.8	I180 V181 L182 L187 V188 Y286 L290 S443 V446 C447 L450	I180-L184 HydrophobicContact CG2-CG 4.45Å; I180-L184 VanDerWaalsContact O-CG 3.29Å; I180-L184 WeakPolarHBondContact O-CG 3.37Å; I180-L184 PolarHBondContact O-N 2.83Å; V181-L184 WeakPolarHBondContact O-CB 3.34Å; V181-L184 PolarHBondContact O-N 3.23Å; L182-L184 VanDerWaalsContact C-N 3.33Å; L182-L184 PolarHBondContact O-N 3.42Å; L184-L187 PolarHBondContact O-N 3.07Å; L184-V188 WeakPolarHBondContact O-CG2 3.42Å; L184-V188 PolarHBondContact O-N 3.03Å; L184-Y286 HydrophobicContact CD2-CD1 3.99Å; L184-Y286 HydrophobicContact CD2-CE1 3.29Å; L184-L290 HydrophobicContact CD2-CD1 3.76Å; L184-S443 WeakPolarHBondContact CD1-O 3.18Å; L184-V446 HydrophobicContact CD1-CB 4.36Å; L184-V446 HydrophobicContact CD1-CG1 4.23Å; L184-C447 HydrophobicContact CB-CB 4.47Å; L184-C447 HydrophobicContact CD1-CB 3.93Å; L184-C447 HydrophobicContact CD2-CB 3.63Å; L184-C447 HydrophobicContact CG-CB 4.2Å; L184-L450 HydrophobicContact CB-CD1 4.43Å
185	I	83.3	Confident	86.3	Confident	73 Å²	73	24.5 Å²	24.5	37%	0.374	13%	0.126	S	C	.	.	H	α-helix	trans	-59.6	-50.4	179.3	-65.5	166.5	0	0	0	109.9	V181 L182 L187 V188 D189 L450	V181-I185 HydrophobicContact CG1-CD1 4.36Å; V181-I185 WeakPolarHBondContact O-CG1 3.34Å; V181-I185 PolarHBondContact O-N 3.15Å; V181-I185 VanDerWaalsContact O-N 3.09Å; L182-I185 PolarHBondContact O-N 3.28Å; I185-L187 PolarHBondContact O-N 3.36Å; I185-V188 PolarHBondContact O-N 3.39Å; I185-D189 WeakPolarHBondContact O-CB 3.43Å; I185-D189 PolarHBondContact O-N 3.33Å; I185-L450 HydrophobicContact CD1-CD1 4.47Å; I185-L450 HydrophobicContact CG1-CD1 3.63Å
186	L	84.4	Confident	86.1	Confident	20 Å²	20	26.7 Å²	26.7	11%	0.105	14%	0.136	C	C	.	.	H	α-helix	trans	-63.3	-31	179.8	-69.5	170	0	0	0	112.8	L182 Q183 F190 I344 T348	L182-L186 VanDerWaalsContact O-CG 3.31Å; L182-L186 WeakPolarHBondContact O-CG 3.45Å; L182-L186 PolarHBondContact O-N 3.47Å; Q183-L186 PolarHBondContact O-N 3.49Å; L186-F190 VanDerWaalsContact O-CB 3.26Å; L186-F190 WeakPolarHBondContact O-CB 3.46Å; L186-F190 PolarHBondContact O-N 3.45Å; L186-I344 HydrophobicContact CB-CD1 4.27Å; L186-I344 HydrophobicContact CB-CG2 3.99Å; L186-I344 HydrophobicContact CD1-CG2 3.6Å; L186-I344 HydrophobicContact CG-CG2 4.47Å; L186-T348 WeakPolarHBondContact CD1-OG1 3.37Å
187	L	86.8	Confident	85.9	Confident	13 Å²	13	32.4 Å²	32.4	7%	0.068	16%	0.16	C	C	.	.	H	α-helix	trans	-73.5	-43.9	177.3	-169.6	78.4	0	0	0	112.2	Q183 L184 I185 D189 F190 A191 F282 I283 Y286 I344	Q183-L187 VanDerWaalsContact O-CB 3.24Å; Q183-L187 WeakPolarHBondContact O-CB 3.39Å; Q183-L187 PolarHBondContact O-N 3.31Å; L184-L187 PolarHBondContact O-N 3.07Å; I185-L187 PolarHBondContact O-N 3.36Å; L187-D189 VanDerWaalsContact C-N 3.29Å; L187-D189 PolarHBondContact O-N 3.21Å; L187-F190 WeakPolarHBondContact O-CB 3.2Å; L187-F190 PolarHBondContact O-N 3.12Å; L187-A191 PolarHBondContact O-N 3.12Å; L187-F282 HydrophobicContact CD1-CE1 3.69Å; L187-F282 HydrophobicContact CD1-CZ 4.17Å; L187-F282 HydrophobicContact CD2-CE1 4.27Å; L187-F282 HydrophobicContact CG-CE1 3.83Å; L187-I283 HydrophobicContact CD2-CD1 4.07Å; L187-I283 HydrophobicContact CG-CD1 4.21Å; L187-Y286 HydrophobicContact CD2-CD1 3.09Å; L187-Y286 HydrophobicContact CD2-CD2 3.92Å; L187-Y286 HydrophobicContact CD2-CE1 3.45Å; L187-Y286 VanDerWaalsContact CD2-CE1 3.45Å; L187-Y286 HydrophobicContact CD2-CE2 4.32Å; L187-Y286 HydrophobicContact CD2-CG 3.32Å; L187-I344 HydrophobicContact CB-CD1 4.23Å; L187-I344 HydrophobicContact CD1-CD1 3.98Å
188	V	84.6	Confident	86.1	Confident	7 Å²	7	30.1 Å²	30.1	4%	0.042	15%	0.15	C	C	.	.	H	α-helix	trans	-57	-49.6	172.5	170.1	0	0	0	0	109.2	L184 I185 F190 A191 H192 I283 L451	L184-V188 WeakPolarHBondContact O-CG2 3.42Å; L184-V188 PolarHBondContact O-N 3.03Å; I185-V188 PolarHBondContact O-N 3.39Å; V188-F190 VanDerWaalsContact C-N 3.32Å; V188-F190 PolarHBondContact O-N 2.95Å; V188-A191 WeakPolarHBondContact O-CA 3.45Å; V188-A191 WeakPolarHBondContact O-CB 3.3Å; V188-A191 PolarHBondContact O-N 3.37Å; V188-H192 PolarHBondContact O-CD2 2.64Å; V188-H192 PolarHBondContact O-N 3.14Å; V188-I283 HydrophobicContact CB-CD1 4.39Å; V188-I283 HydrophobicContact CG2-CD1 3.69Å; V188-I283 HydrophobicContact CG2-CG1 4.12Å; V188-L451 HydrophobicContact CG1-CD1 4.35Å
189	D	83	Confident	86	Confident	39 Å²	39	28.8 Å²	28.8	21%	0.209	14%	0.144	C	C	.	.	H	α-helix	trans	-63	-36.8	-179.3	-163	27.9	0	0	0	112.9	I185 L187 S193 R351	I185-D189 WeakPolarHBondContact O-CB 3.43Å; I185-D189 PolarHBondContact O-N 3.33Å; L187-D189 VanDerWaalsContact C-N 3.29Å; L187-D189 PolarHBondContact O-N 3.21Å; D189-S193 WeakPolarHBondContact O-CB 3.34Å; D189-S193 PolarHBondContact O-N 3Å; D189-S193 PolarHBondContact O-OG 2.97Å; D189-R351 VanDerWaalsContact C-NH1 3.32Å; D189-R351 PolarHBondContact O-NH1 3.48Å; D189-R351 IonicContact OD1-CZ 3.67Å; D189-R351 IonicContact OD1-NE 2.66Å; D189-R351 IonicContact OD1-NH1 3.16Å; D189-R351 PolarHBondContact OD1-NH1 2.75Å; D189-R351 IonicContact OD1-NH2 3.85Å; D189-R351 PolarHBondContact OD1-NH2 3.41Å; D189-R351 WeakPolarHBondContact OD2-CD 3.22Å; D189-R351 IonicContact OD2-CZ 3.94Å; D189-R351 IonicContact OD2-NE 2.82Å; D189-R351 PolarHBondContact OD2-NE 3.37Å; D189-R351 IonicContact OD2-NH1 2.93Å; D189-R351 PolarHBondContact OD2-NH1 2.82Å; D189-R351 IonicContact OD2-NH2 3.7Å; D189-R351 PolarHBondContact OD2-NH2 3.01Å
190	F	85.8	Confident	85.8	Confident	66 Å²	66	31.9 Å²	31.9	29%	0.289	16%	0.158	S	C	.	.	H	α-helix	trans	-63.1	-45.6	169.3	169.1	-100.5	0	0	0	112.3	L186 L187 V188 H192 S193 L194 F282 Y347	L186-F190 VanDerWaalsContact O-CB 3.26Å; L186-F190 WeakPolarHBondContact O-CB 3.46Å; L186-F190 PolarHBondContact O-N 3.45Å; L187-F190 WeakPolarHBondContact O-CB 3.2Å; L187-F190 PolarHBondContact O-N 3.12Å; V188-F190 VanDerWaalsContact C-N 3.32Å; V188-F190 PolarHBondContact O-N 2.95Å; F190-H192 VanDerWaalsContact C-N 3.34Å; F190-H192 PolarHBondContact O-N 3.06Å; F190-S193 PolarHBondContact O-N 3.43Å; F190-L194 HydrophobicContact CE1-CD2 4.04Å; F190-L194 HydrophobicContact CZ-CD2 3.88Å; F190-L194 VanDerWaalsContact O-CB 3.26Å; F190-L194 WeakPolarHBondContact O-CB 3.38Å; F190-L194 PolarHBondContact O-N 3.42Å; F190-F282 HydrophobicContact CD1-CE1 4.11Å; F190-F282 HydrophobicContact CD1-CZ 4.11Å; F190-F282 HydrophobicContact CE1-CE1 4.35Å; F190-F282 AromaticContact CE1-CZ 3.91Å; F190-F282 HydrophobicContact CE1-CZ 3.91Å; F190-Y347 WeakPolarHBondContact CA-OH 3.14Å; F190-Y347 HydrophobicContact CB-CD1 4.31Å; F190-Y347 HydrophobicContact CB-CE1 3.82Å; F190-Y347 HydrophobicContact CB-CE2 4.33Å; F190-Y347 AromaticContact CD2-CD2 3.83Å; F190-Y347 HydrophobicContact CD2-CD2 3.83Å; F190-Y347 AromaticContact CD2-CE2 3.62Å; F190-Y347 HydrophobicContact CD2-CE2 3.62Å; F190-Y347 HydrophobicContact CD2-CG 4.39Å; F190-Y347 AromaticContact CD2-CZ 3.98Å; F190-Y347 HydrophobicContact CE2-CE2 4.5Å; F190-Y347 HydrophobicContact CG-CE2 4.47Å
191	A	87.6	Confident	85.8	Confident	1 Å²	1	34.9 Å²	34.9	1%	0.008	17%	0.171	C	C	.	.	H	α-helix	trans	-62.1	-42.7	179.4	0	0	0	0	0	111.4	L187 V188 L194 A195 Q279 F282	L187-A191 PolarHBondContact O-N 3.12Å; V188-A191 WeakPolarHBondContact O-CA 3.45Å; V188-A191 WeakPolarHBondContact O-CB 3.3Å; V188-A191 PolarHBondContact O-N 3.37Å; A191-L194 PolarHBondContact O-N 3.08Å; A191-A195 WeakPolarHBondContact O-CB 3.42Å; A191-A195 PolarHBondContact O-N 2.97Å; A191-Q279 HydrophobicContact CB-CG 4.43Å; A191-F282 HydrophobicContact CB-CD1 3.75Å; A191-F282 HydrophobicContact CB-CE1 4.36Å; A191-F282 HydrophobicContact CB-CG 4.37Å
192	H	83.5	Confident	85.9	Confident	11 Å²	11	37.5 Å²	37.5	5%	0.051	18%	0.177	C	C	.	.	H	α-helix	trans	-60.8	-54.7	173.5	-76.6	-75.8	0	0	0	111.4	V188 F190 L194 A195 E196 Q279 D454	V188-H192 PolarHBondContact O-CD2 2.64Å; V188-H192 PolarHBondContact O-N 3.14Å; F190-H192 VanDerWaalsContact C-N 3.34Å; F190-H192 PolarHBondContact O-N 3.06Å; H192-L194 PolarHBondContact O-N 3.39Å; H192-A195 WeakPolarHBondContact O-CB 3.48Å; H192-A195 PolarHBondContact O-N 3.47Å; H192-A195 VanDerWaalsContact O-N 3.09Å; H192-E196 WeakPolarHBondContact O-CG 3.43Å; H192-E196 PolarHBondContact O-N 3.23Å; H192-Q279 VanDerWaalsContact CE1-CD 3.41Å; H192-Q279 PolarHBondContact CE1-OE1 3.34Å; H192-Q279 VanDerWaalsContact CE1-OE1 3.26Å; H192-Q279 PolarHBondContact ND1-NE2 3.29Å; H192-Q279 PolarHBondContact ND1-OE1 2.86Å; H192-D454 IonicContact CD2-OD2 3.97Å; H192-D454 IonicContact NE2-OD2 2.87Å
193	S	83.2	Confident	86	Confident	16 Å²	16	41.7 Å²	41.7	11%	0.112	20%	0.196	C	C	.	.	H	α-helix	trans	-60.5	-31.9	179.3	-75.1	0	0	0	0	114.1	D189 F190 K197 R351	D189-S193 WeakPolarHBondContact O-CB 3.34Å; D189-S193 PolarHBondContact O-N 3Å; D189-S193 PolarHBondContact O-OG 2.97Å; F190-S193 PolarHBondContact O-N 3.43Å; S193-K197 WeakPolarHBondContact O-CB 3.48Å; S193-K197 WeakPolarHBondContact O-CD 3.33Å; S193-K197 WeakPolarHBondContact O-CG 3.29Å; S193-K197 PolarHBondContact O-N 2.85Å; S193-K197 VanDerWaalsContact O-N 3.16Å; S193-R351 PolarHBondContact OG-NH1 2.85Å
194	L	86.4	Confident	86	Confident	44 Å²	44	49.2 Å²	49.2	23%	0.23	23%	0.231	C	C	.	.	H	α-helix	trans	-71	-42.9	176.3	-175.9	59.5	0	0	0	110.8	F190 A191 H192 K197 F198 F278	F190-L194 HydrophobicContact CE1-CD2 4.04Å; F190-L194 HydrophobicContact CZ-CD2 3.88Å; F190-L194 VanDerWaalsContact O-CB 3.26Å; F190-L194 WeakPolarHBondContact O-CB 3.38Å; F190-L194 PolarHBondContact O-N 3.42Å; A191-L194 PolarHBondContact O-N 3.08Å; H192-L194 PolarHBondContact O-N 3.39Å; L194-K197 PolarHBondContact O-N 3.13Å; L194-F198 HydrophobicContact CD1-CD2 3.89Å; L194-F198 HydrophobicContact CD1-CE2 3.4Å; L194-F198 HydrophobicContact CD1-CZ 4.21Å; L194-F198 HydrophobicContact CD2-CE2 4.21Å; L194-F198 HydrophobicContact CG-CD2 3.89Å; L194-F198 HydrophobicContact CG-CE2 3.6Å; L194-F198 WeakPolarHBondContact O-CD2 3.48Å; L194-F198 PolarHBondContact O-N 3.24Å; L194-F198 VanDerWaalsContact O-N 3.11Å; L194-F278 HydrophobicContact CB-CE1 4.28Å; L194-F278 HydrophobicContact CD2-CE1 4.07Å; L194-F278 HydrophobicContact CD2-CZ 3.79Å; L194-F278 HydrophobicContact CG-CE1 4.19Å; L194-F278 HydrophobicContact CG-CZ 4.37Å
195	A	88.2	Confident	86.1	Confident	4 Å²	4	52.2 Å²	52.2	3%	0.033	25%	0.25	C	C	.	.	H	α-helix	trans	-60.1	-49.6	175.1	0	0	0	0	0	111.5	A191 H192 K197 F198 I199 F278 Q279	A191-A195 WeakPolarHBondContact O-CB 3.42Å; A191-A195 PolarHBondContact O-N 2.97Å; H192-A195 WeakPolarHBondContact O-CB 3.48Å; H192-A195 PolarHBondContact O-N 3.47Å; H192-A195 VanDerWaalsContact O-N 3.09Å; A195-K197 VanDerWaalsContact C-N 3.32Å; A195-K197 PolarHBondContact O-N 2.81Å; A195-F198 PolarHBondContact O-N 2.93Å; A195-F198 VanDerWaalsContact O-N 3.14Å; A195-I199 VanDerWaalsContact O-CG1 3.3Å; A195-I199 WeakPolarHBondContact O-CG1 3.43Å; A195-I199 PolarHBondContact O-N 3.04Å; A195-F278 HydrophobicContact CB-CD1 3.96Å; A195-Q279 HydrophobicContact CB-CG 4.07Å; A195-Q279 VanDerWaalsContact CB-NE2 3.33Å
196	E	85.1	Confident	86.1	Confident	51 Å²	51	56.7 Å²	56.7	24%	0.238	27%	0.269	C	S	.	.	H	α-helix	trans	-56.1	-46.5	178.2	-67.9	178.6	155	0	0	111	H192 F198 I199 E200 K274	H192-E196 WeakPolarHBondContact O-CG 3.43Å; H192-E196 PolarHBondContact O-N 3.23Å; E196-F198 VanDerWaalsContact C-N 3.34Å; E196-F198 PolarHBondContact O-N 3.43Å; E196-I199 PolarHBondContact O-N 3.23Å; E196-E200 WeakPolarHBondContact O-CB 3.31Å; E196-E200 VanDerWaalsContact O-CG 3.26Å; E196-E200 WeakPolarHBondContact O-CG 3.38Å; E196-E200 PolarHBondContact O-N 3.43Å; E196-K274 HydrophobicContact CB-CD 4.3Å; E196-K274 HydrophobicContact CG-CB 4.18Å; E196-K274 HydrophobicContact CG-CD 3.82Å
197	K	85	Confident	86.2	Confident	120 Å²	120	63.1 Å²	63.1	52%	0.522	29%	0.292	S	S	.	.	H	α-helix	trans	-63.1	-35.9	178.2	-76.7	172.2	-176.3	175	0	113.8	S193 L194 A195 K201	S193-K197 WeakPolarHBondContact O-CB 3.48Å; S193-K197 WeakPolarHBondContact O-CD 3.33Å; S193-K197 WeakPolarHBondContact O-CG 3.29Å; S193-K197 PolarHBondContact O-N 2.85Å; S193-K197 VanDerWaalsContact O-N 3.16Å; L194-K197 PolarHBondContact O-N 3.13Å; A195-K197 VanDerWaalsContact C-N 3.32Å; A195-K197 PolarHBondContact O-N 2.81Å; K197-K201 WeakPolarHBondContact O-CB 3.37Å; K197-K201 VanDerWaalsContact O-CG 3.27Å; K197-K201 WeakPolarHBondContact O-CG 3.19Å; K197-K201 PolarHBondContact O-N 2.76Å
198	F	88.4	Confident	86.3	Confident	27 Å²	27	72.5 Å²	72.5	12%	0.118	33%	0.326	C	S	.	.	H	α-helix	trans	-71	-40.1	176.4	-82.6	-63.2	0	0	0	111.5	L194 A195 E196 Y202 W210 A213 L214 F217	L194-F198 HydrophobicContact CD1-CD2 3.89Å; L194-F198 HydrophobicContact CD1-CE2 3.4Å; L194-F198 HydrophobicContact CD1-CZ 4.21Å; L194-F198 HydrophobicContact CD2-CE2 4.21Å; L194-F198 HydrophobicContact CG-CD2 3.89Å; L194-F198 HydrophobicContact CG-CE2 3.6Å; L194-F198 WeakPolarHBondContact O-CD2 3.48Å; L194-F198 PolarHBondContact O-N 3.24Å; L194-F198 VanDerWaalsContact O-N 3.11Å; A195-F198 PolarHBondContact O-N 2.93Å; A195-F198 VanDerWaalsContact O-N 3.14Å; E196-F198 VanDerWaalsContact C-N 3.34Å; E196-F198 PolarHBondContact O-N 3.43Å; F198-Y202 WeakPolarHBondContact O-CB 3.44Å; F198-Y202 PolarHBondContact O-N 3.46Å; F198-Y202 VanDerWaalsContact O-N 3.09Å; F198-W210 AromaticContact CD1-CE3 3.67Å; F198-W210 HydrophobicContact CD1-CE3 3.67Å; F198-W210 HydrophobicContact CD1-CZ3 4.19Å; F198-W210 AromaticContact CE1-CE3 3.74Å; F198-W210 HydrophobicContact CE1-CE3 3.74Å; F198-W210 AromaticContact CE1-CZ3 3.88Å; F198-W210 HydrophobicContact CE1-CZ3 3.88Å; F198-A213 HydrophobicContact CE1-CB 4.19Å; F198-L214 HydrophobicContact CB-CB 4.34Å; F198-L214 HydrophobicContact CB-CD1 4.07Å; F198-L214 HydrophobicContact CD2-CD1 4.17Å; F198-L214 HydrophobicContact CG-CD1 4.41Å; F198-F217 HydrophobicContact CE2-CD2 4.2Å; F198-F217 HydrophobicContact CE2-CE2 4.35Å; F198-F217 HydrophobicContact CZ-CD2 4.07Å; F198-F217 AromaticContact CZ-CE2 3.82Å; F198-F217 HydrophobicContact CZ-CE2 3.82Å
199	I	87.1	Confident	86.6	Confident	36 Å²	36	78 Å²	78	19%	0.185	35%	0.354	C	S	.	.	H	α-helix	trans	-67.2	-49	177.4	-65.7	166.6	0	0	0	110.3	A195 E196 K201 Y202 E203 L214 K274	A195-I199 VanDerWaalsContact O-CG1 3.3Å; A195-I199 WeakPolarHBondContact O-CG1 3.43Å; A195-I199 PolarHBondContact O-N 3.04Å; E196-I199 PolarHBondContact O-N 3.23Å; I199-K201 VanDerWaalsContact C-N 3.34Å; I199-K201 PolarHBondContact O-N 2.66Å; I199-Y202 CarbonylContact O-C 3.59Å; I199-Y202 WeakPolarHBondContact O-CA 3.47Å; I199-Y202 WeakPolarHBondContact O-CB 3.26Å; I199-Y202 PolarHBondContact O-N 2.95Å; I199-E203 HydrophobicContact CG2-CG 4.45Å; I199-E203 WeakPolarHBondContact O-CG 3.24Å; I199-E203 PolarHBondContact O-N 3.5Å; I199-L214 HydrophobicContact CG1-CD2 4Å; I199-K274 HydrophobicContact CD1-CB 4.34Å
200	E	86.6	Confident	86.9	Confident	67 Å²	67	79.7 Å²	79.7	31%	0.313	36%	0.358	S	S	.	.	H	α-helix	trans	-58.8	-44.2	178.3	-75.4	166.6	-172.5	0	0	111.6	E196 Y202 E203 E204 K274	E196-E200 WeakPolarHBondContact O-CB 3.31Å; E196-E200 VanDerWaalsContact O-CG 3.26Å; E196-E200 WeakPolarHBondContact O-CG 3.38Å; E196-E200 PolarHBondContact O-N 3.43Å; E200-Y202 VanDerWaalsContact C-N 3.27Å; E200-Y202 PolarHBondContact O-N 2.92Å; E200-E203 PolarHBondContact O-N 3.24Å; E200-E204 WeakPolarHBondContact O-CB 3.26Å; E200-E204 WeakPolarHBondContact O-CG 3.4Å; E200-E204 PolarHBondContact O-N 2.9Å; E200-K274 IonicContact OE1-NZ 3.71Å; E200-K274 PolarHBondContact OE1-NZ 3.38Å
201	K	87.6	Confident	86.9	Confident	69 Å²	69	80.5 Å²	80.5	30%	0.3	36%	0.364	S	S	.	.	H	α-helix	trans	-65	-32	175.3	-78.3	-175.1	174.9	-162	0	113.7	K197 I199 T205 W210	K197-K201 WeakPolarHBondContact O-CB 3.37Å; K197-K201 VanDerWaalsContact O-CG 3.27Å; K197-K201 WeakPolarHBondContact O-CG 3.19Å; K197-K201 PolarHBondContact O-N 2.76Å; I199-K201 VanDerWaalsContact C-N 3.34Å; I199-K201 PolarHBondContact O-N 2.66Å; K201-T205 VanDerWaalsContact O-CB 3.29Å; K201-T205 WeakPolarHBondContact O-CB 3.42Å; K201-T205 PolarHBondContact O-N 2.88Å; K201-T205 PolarHBondContact O-OG1 2.98Å; K201-W210 HydrophobicContact CB-CD2 4.02Å; K201-W210 HydrophobicContact CB-CG 4.02Å; K201-W210 HydrophobicContact CD-CD2 4.17Å; K201-W210 HydrophobicContact CD-CE3 4.23Å; K201-W210 HydrophobicContact CD-CH2 3.82Å; K201-W210 HydrophobicContact CD-CZ2 3.73Å; K201-W210 HydrophobicContact CD-CZ3 4.06Å
202	Y	87.7	Confident	87.1	Confident	88 Å²	88	83.2 Å²	83.2	35%	0.345	39%	0.386	S	S	.	.	H	α-helix	trans	-68.8	-43.6	174.2	173.9	-112.2	0	0	0	110.7	F198 I199 E200 E206 R207 M211	F198-Y202 WeakPolarHBondContact O-CB 3.44Å; F198-Y202 PolarHBondContact O-N 3.46Å; F198-Y202 VanDerWaalsContact O-N 3.09Å; I199-Y202 CarbonylContact O-C 3.59Å; I199-Y202 WeakPolarHBondContact O-CA 3.47Å; I199-Y202 WeakPolarHBondContact O-CB 3.26Å; I199-Y202 PolarHBondContact O-N 2.95Å; E200-Y202 VanDerWaalsContact C-N 3.27Å; E200-Y202 PolarHBondContact O-N 2.92Å; Y202-E206 WeakPolarHBondContact O-CA 3.36Å; Y202-E206 PolarHBondContact O-N 2.93Å; Y202-R207 WeakPolarHBondContact CD2-O 3.36Å; Y202-M211 HydrophobicContact CD2-CB 4.01Å; Y202-M211 HydrophobicContact CE2-CB 4.13Å; Y202-M211 HydrophobicContact CG-CB 4.3Å
203	E	87.7	Confident	87.4	Confident	123 Å²	123	83.9 Å²	83.9	58%	0.575	39%	0.393	S	S	*	.	H	α-helix	trans	-64.1	-41.5	175.8	-69.7	173	174.6	0	0	112.1	I199 E200	I199-E203 HydrophobicContact CG2-CG 4.45Å; I199-E203 WeakPolarHBondContact O-CG 3.24Å; I199-E203 PolarHBondContact O-N 3.5Å; E200-E203 PolarHBondContact O-N 3.24Å
204	E	88.2	Confident	87.8	Confident	159 Å²	159	84.1 Å²	84.1	74%	0.743	39%	0.393	S	S	*	.	H	α-helix	trans	-74.4	-42	-179.7	-73.1	176.8	174.1	0	0	113.7	E200	E200-E204 WeakPolarHBondContact O-CB 3.26Å; E200-E204 WeakPolarHBondContact O-CG 3.4Å; E200-E204 PolarHBondContact O-N 2.9Å
205	T	87.4	Confident	88	Confident	63 Å²	63	86.4 Å²	86.4	39%	0.387	41%	0.405	S	S	.	.	H	α-helix	trans	-96	-14.3	-172.8	-31.7	0	0	0	0	112.5	K201 R207	K201-T205 VanDerWaalsContact O-CB 3.29Å; K201-T205 WeakPolarHBondContact O-CB 3.42Å; K201-T205 PolarHBondContact O-N 2.88Å; K201-T205 PolarHBondContact O-OG1 2.98Å; T205-R207 HydrophobicContact CG2-CB 4.22Å; T205-R207 HydrophobicContact CG2-CG 3.64Å; T205-R207 PolarHBondContact O-N 3.23Å
206	E	83.4	Confident	88.2	Confident	166 Å²	166	92.3 Å²	92.3	78%	0.776	43%	0.43	S	S	*	.			trans	51.4	13.2	-167.7	-62.1	-169.9	162.3	0	0	114.7	Y202 R208	Y202-E206 WeakPolarHBondContact O-CA 3.36Å; Y202-E206 PolarHBondContact O-N 2.93Å; E206-R208 PolarHBondContact O-N 2.91Å
207	R	86.8	Confident	88.5	Confident	155 Å²	155	93.9 Å²	93.9	59%	0.585	44%	0.436	S	S	*	.			trans	-81.4	113.5	-177.4	-75.8	-175.2	-172.3	-149	1	110.6	Y202 T205 I209 W210	Y202-R207 WeakPolarHBondContact CD2-O 3.36Å; T205-R207 HydrophobicContact CG2-CB 4.22Å; T205-R207 HydrophobicContact CG2-CG 3.64Å; T205-R207 PolarHBondContact O-N 3.23Å; R207-I209 PolarHBondContact O-N 3.11Å; R207-W210 PolarHBondContact O-N 2.94Å; R207-W210 VanDerWaalsContact O-N 3.1Å
208	R	88.9	Confident	88.8	Confident	210 Å²	210	88.6 Å²	88.6	79%	0.792	42%	0.415	S	S	*	.	H	α-helix	trans	-52.9	-20.2	175.8	-62.7	-176	-177.2	-176.8	0.2	115.1	E206 W210 M211 A212	E206-R208 PolarHBondContact O-N 2.91Å; R208-W210 VanDerWaalsContact C-N 3.27Å; R208-W210 PolarHBondContact O-N 3.21Å; R208-M211 PolarHBondContact O-N 3.08Å; R208-A212 WeakPolarHBondContact O-CB 3.28Å; R208-A212 PolarHBondContact O-N 3.23Å
209	I	91.1	Very high	89.1	Confident	122 Å²	122	91.7 Å²	91.7	63%	0.626	44%	0.436	S	S	*	.	H	α-helix	trans	-58.2	-39.2	176.6	-61.5	172.6	0	0	0	111.3	R207 A212 A213	R207-I209 PolarHBondContact O-N 3.11Å; I209-A212 PolarHBondContact O-N 3.36Å; I209-A213 WeakPolarHBondContact O-CB 3.48Å; I209-A213 PolarHBondContact O-N 3.42Å
210	W	88.7	Confident	89.4	Confident	76 Å²	76	94 Å²	94	29%	0.288	45%	0.448	S	S	.	.	H	α-helix	trans	-68.8	-39	-179.5	-65.9	119.4	0	0	0	112.2	F198 K201 R207 R208 A213 L214	F198-W210 AromaticContact CD1-CE3 3.67Å; F198-W210 HydrophobicContact CD1-CE3 3.67Å; F198-W210 HydrophobicContact CD1-CZ3 4.19Å; F198-W210 AromaticContact CE1-CE3 3.74Å; F198-W210 HydrophobicContact CE1-CE3 3.74Å; F198-W210 AromaticContact CE1-CZ3 3.88Å; F198-W210 HydrophobicContact CE1-CZ3 3.88Å; K201-W210 HydrophobicContact CB-CD2 4.02Å; K201-W210 HydrophobicContact CB-CG 4.02Å; K201-W210 HydrophobicContact CD-CD2 4.17Å; K201-W210 HydrophobicContact CD-CE3 4.23Å; K201-W210 HydrophobicContact CD-CH2 3.82Å; K201-W210 HydrophobicContact CD-CZ2 3.73Å; K201-W210 HydrophobicContact CD-CZ3 4.06Å; R207-W210 PolarHBondContact O-N 2.94Å; R207-W210 VanDerWaalsContact O-N 3.1Å; R208-W210 VanDerWaalsContact C-N 3.27Å; R208-W210 PolarHBondContact O-N 3.21Å; W210-A213 PolarHBondContact O-N 2.97Å; W210-L214 PolarHBondContact O-N 2.65Å
211	M	87.2	Confident	89.8	Confident	83 Å²	83	91.2 Å²	91.2	41%	0.409	44%	0.436	S	S	.	.	H	α-helix	trans	-66.7	-43.7	172.9	-172.1	62.1	179.8	0	0	111.7	Y202 R208 A213 L214 I215	Y202-M211 HydrophobicContact CD2-CB 4.01Å; Y202-M211 HydrophobicContact CE2-CB 4.13Å; Y202-M211 HydrophobicContact CG-CB 4.3Å; R208-M211 PolarHBondContact O-N 3.08Å; M211-A213 VanDerWaalsContact C-N 3.3Å; M211-A213 PolarHBondContact O-N 3.45Å; M211-L214 PolarHBondContact O-N 2.97Å; M211-L214 HydrophobicContact SD-CD2 4.41Å; M211-I215 HydrophobicContact CE-CD1 4.16Å; M211-I215 HydrophobicContact CE-CG1 4.36Å; M211-I215 HydrophobicContact CG-CD1 4.19Å; M211-I215 WeakPolarHBondContact O-CG1 3.31Å; M211-I215 PolarHBondContact O-N 3.32Å
212	A	91	Very high	90.1	Very high	58 Å²	58	90.3 Å²	90.3	48%	0.479	43%	0.431	S	S	.	.	H	α-helix	trans	-60.9	-39.3	175.5	0	0	0	0	0	112	R208 I209 I215 F216	R208-A212 WeakPolarHBondContact O-CB 3.28Å; R208-A212 PolarHBondContact O-N 3.23Å; I209-A212 PolarHBondContact O-N 3.36Å; A212-I215 PolarHBondContact O-N 2.93Å; A212-F216 VanDerWaalsContact O-CB 3.26Å; A212-F216 WeakPolarHBondContact O-CB 3.44Å; A212-F216 PolarHBondContact O-N 3.46Å
213	A	90.7	Very high	90.4	Very high	25 Å²	25	88.6 Å²	88.6	21%	0.207	44%	0.435	C	S	.	.	H	α-helix	trans	-63.6	-44.2	174.7	0	0	0	0	0	111.8	F198 I209 W210 M211 I215 F216 F217	F198-A213 HydrophobicContact CE1-CB 4.19Å; I209-A213 WeakPolarHBondContact O-CB 3.48Å; I209-A213 PolarHBondContact O-N 3.42Å; W210-A213 PolarHBondContact O-N 2.97Å; M211-A213 VanDerWaalsContact C-N 3.3Å; M211-A213 PolarHBondContact O-N 3.45Å; A213-I215 PolarHBondContact O-N 3.05Å; A213-F216 PolarHBondContact O-N 3.37Å; A213-F217 HydrophobicContact CB-CE2 4.47Å; A213-F217 WeakPolarHBondContact O-CD2 3.26Å; A213-F217 PolarHBondContact O-N 2.84Å
214	L	90	Very high	90.7	Very high	20 Å²	20	85.7 Å²	85.7	11%	0.105	43%	0.426	C	S	.	.	H	α-helix	trans	-60.4	-46.1	177.1	-175.1	66.6	0	0	0	111.7	F198 I199 W210 M211 F217 A218 F278	F198-L214 HydrophobicContact CB-CB 4.34Å; F198-L214 HydrophobicContact CB-CD1 4.07Å; F198-L214 HydrophobicContact CD2-CD1 4.17Å; F198-L214 HydrophobicContact CG-CD1 4.41Å; I199-L214 HydrophobicContact CG1-CD2 4Å; W210-L214 PolarHBondContact O-N 2.65Å; M211-L214 PolarHBondContact O-N 2.97Å; M211-L214 HydrophobicContact SD-CD2 4.41Å; L214-F217 PolarHBondContact O-N 3.16Å; L214-A218 WeakPolarHBondContact O-CB 3.5Å; L214-A218 PolarHBondContact O-N 3.17Å; L214-F278 HydrophobicContact CD1-CB 3.93Å; L214-F278 HydrophobicContact CD1-CD1 3.91Å; L214-F278 HydrophobicContact CD1-CG 3.83Å
215	I	90.6	Very high	91	Very high	92 Å²	92	78.5 Å²	78.5	47%	0.472	39%	0.393	S	S	.	.	H	α-helix	trans	-63.2	-44.2	176.4	-65.4	168.3	0	0	0	110.6	M211 A212 A213 F217 A218 V219	M211-I215 HydrophobicContact CE-CD1 4.16Å; M211-I215 HydrophobicContact CE-CG1 4.36Å; M211-I215 HydrophobicContact CG-CD1 4.19Å; M211-I215 WeakPolarHBondContact O-CG1 3.31Å; M211-I215 PolarHBondContact O-N 3.32Å; A212-I215 PolarHBondContact O-N 2.93Å; A213-I215 PolarHBondContact O-N 3.05Å; I215-F217 PolarHBondContact O-N 3.42Å; I215-A218 WeakPolarHBondContact O-CB 3.44Å; I215-A218 PolarHBondContact O-N 3.37Å; I215-V219 HydrophobicContact CG2-CG2 4.29Å; I215-V219 WeakPolarHBondContact O-CG2 3.43Å; I215-V219 PolarHBondContact O-N 2.89Å
216	F	93	Very high	91.3	Very high	128 Å²	128	80.6 Å²	80.6	56%	0.561	40%	0.401	S	S	*	.	H	α-helix	trans	-58.1	-48.1	177.9	173.7	-97.6	0	0	0	111.7	A212 A213 A218 V219 L220	A212-F216 VanDerWaalsContact O-CB 3.26Å; A212-F216 WeakPolarHBondContact O-CB 3.44Å; A212-F216 PolarHBondContact O-N 3.46Å; A213-F216 PolarHBondContact O-N 3.37Å; F216-A218 VanDerWaalsContact C-N 3.32Å; F216-A218 PolarHBondContact O-N 2.93Å; F216-V219 PolarHBondContact O-N 3.39Å; F216-L220 HydrophobicContact CE1-CD2 4.34Å; F216-L220 WeakPolarHBondContact O-CB 3.36Å; F216-L220 PolarHBondContact O-N 2.88Å
217	F	91.5	Very high	91.9	Very high	84 Å²	84	75 Å²	75	37%	0.368	38%	0.383	S	S	.	.	H	α-helix	trans	-65.6	-35	177.3	-74	-60.6	0	0	0	112.5	F198 A213 L214 I215 S221 F278	F198-F217 HydrophobicContact CE2-CD2 4.2Å; F198-F217 HydrophobicContact CE2-CE2 4.35Å; F198-F217 HydrophobicContact CZ-CD2 4.07Å; F198-F217 AromaticContact CZ-CE2 3.82Å; F198-F217 HydrophobicContact CZ-CE2 3.82Å; A213-F217 HydrophobicContact CB-CE2 4.47Å; A213-F217 WeakPolarHBondContact O-CD2 3.26Å; A213-F217 PolarHBondContact O-N 2.84Å; L214-F217 PolarHBondContact O-N 3.16Å; I215-F217 PolarHBondContact O-N 3.42Å; F217-S221 WeakPolarHBondContact O-CB 3.27Å; F217-S221 PolarHBondContact O-N 3.36Å; F217-S221 PolarHBondContact O-OG 3.37Å; F217-F278 HydrophobicContact CB-CD2 3.96Å; F217-F278 HydrophobicContact CB-CE2 3.6Å
218	A	91.8	Very high	92.2	Very high	9 Å²	9	69 Å²	69	7%	0.074	36%	0.363	C	S	.	.	H	α-helix	trans	-63.2	-51.8	173.9	0	0	0	0	0	111.2	L214 I215 F216 L220 S221 Y222 F278	L214-A218 WeakPolarHBondContact O-CB 3.5Å; L214-A218 PolarHBondContact O-N 3.17Å; I215-A218 WeakPolarHBondContact O-CB 3.44Å; I215-A218 PolarHBondContact O-N 3.37Å; F216-A218 VanDerWaalsContact C-N 3.32Å; F216-A218 PolarHBondContact O-N 2.93Å; A218-L220 VanDerWaalsContact C-N 3.32Å; A218-L220 PolarHBondContact O-N 3.32Å; A218-S221 PolarHBondContact O-N 3.37Å; A218-S221 VanDerWaalsContact O-N 3.16Å; A218-S221 PolarHBondContact O-OG 3.1Å; A218-Y222 WeakPolarHBondContact O-CD2 3.43Å; A218-Y222 PolarHBondContact O-N 3.38Å; A218-Y222 VanDerWaalsContact O-N 3.15Å; A218-F278 HydrophobicContact CB-CB 4.01Å; A218-F278 HydrophobicContact CB-CD2 4.25Å
219	V	93.7	Very high	92.5	Very high	93 Å²	93	59.7 Å²	59.7	56%	0.564	33%	0.329	S	S	*	.	H	α-helix	trans	-59.4	-43.9	178.4	172.7	0	0	0	0	111.1	I215 F216 S221 Y222 A223	I215-V219 HydrophobicContact CG2-CG2 4.29Å; I215-V219 WeakPolarHBondContact O-CG2 3.43Å; I215-V219 PolarHBondContact O-N 2.89Å; F216-V219 PolarHBondContact O-N 3.39Å; V219-S221 VanDerWaalsContact C-N 3.32Å; V219-S221 PolarHBondContact O-N 2.87Å; V219-Y222 PolarHBondContact O-N 3.25Å; V219-A223 WeakPolarHBondContact O-CB 3.2Å; V219-A223 PolarHBondContact O-N 3.43Å
220	L	94.4	Very high	92.6	Very high	84 Å²	84	57.5 Å²	57.5	44%	0.44	32%	0.321	S	S	.	.	H	α-helix	trans	-58.7	-44.6	177.1	-178.2	61.9	0	0	0	111.5	F216 A218 A223 T224	F216-L220 HydrophobicContact CE1-CD2 4.34Å; F216-L220 WeakPolarHBondContact O-CB 3.36Å; F216-L220 PolarHBondContact O-N 2.88Å; A218-L220 VanDerWaalsContact C-N 3.32Å; A218-L220 PolarHBondContact O-N 3.32Å; L220-A223 PolarHBondContact O-N 3.11Å; L220-T224 PolarHBondContact O-N 2.79Å; L220-T224 PolarHBondContact O-OG1 2.91Å
221	S	93.7	Very high	92.8	Very high	9 Å²	9	58 Å²	58	6%	0.063	33%	0.329	C	S	.	.	H	α-helix	trans	-62.7	-43.6	179.9	69.4	0	0	0	0	113.1	F217 A218 V219 T224 A225 G281 F282	F217-S221 WeakPolarHBondContact O-CB 3.27Å; F217-S221 PolarHBondContact O-N 3.36Å; F217-S221 PolarHBondContact O-OG 3.37Å; A218-S221 PolarHBondContact O-N 3.37Å; A218-S221 VanDerWaalsContact O-N 3.16Å; A218-S221 PolarHBondContact O-OG 3.1Å; V219-S221 VanDerWaalsContact C-N 3.32Å; V219-S221 PolarHBondContact O-N 2.87Å; S221-T224 PolarHBondContact O-N 3.15Å; S221-A225 WeakPolarHBondContact O-CB 3.32Å; S221-A225 PolarHBondContact O-N 3.27Å; S221-G281 VanDerWaalsContact CB-C 3.49Å; S221-G281 WeakPolarHBondContact OG-CA 3.44Å; S221-F282 PolarHBondContact OG-N 3.4Å
222	Y	94.5	Very high	93	Very high	50 Å²	50	54.2 Å²	54.2	20%	0.196	31%	0.31	C	S	.	.	H	α-helix	trans	-68.7	-39.2	174.9	-78.1	-76.9	0	0	0	112.4	A218 V219 T224 A225 I226 S260 L277 A280 G281	A218-Y222 WeakPolarHBondContact O-CD2 3.43Å; A218-Y222 PolarHBondContact O-N 3.38Å; A218-Y222 VanDerWaalsContact O-N 3.15Å; V219-Y222 PolarHBondContact O-N 3.25Å; Y222-T224 VanDerWaalsContact C-N 3.32Å; Y222-T224 PolarHBondContact O-N 3.43Å; Y222-A225 PolarHBondContact O-N 2.75Å; Y222-I226 WeakPolarHBondContact O-CB 3.37Å; Y222-I226 VanDerWaalsContact O-CG1 3.27Å; Y222-I226 WeakPolarHBondContact O-CG1 3.37Å; Y222-I226 PolarHBondContact O-N 3.02Å; Y222-S260 PolarHBondContact OH-OG 3.28Å; Y222-S260 VanDerWaalsContact OH-OG 3.09Å; Y222-L277 HydrophobicContact CE2-CD1 3.8Å; Y222-L277 HydrophobicContact CE2-CD2 4.31Å; Y222-L277 HydrophobicContact CE2-CG 3.64Å; Y222-L277 WeakPolarHBondContact CE2-O 3.46Å; Y222-L277 WeakPolarHBondContact OH-CD1 3.38Å; Y222-L277 PolarHBondContact OH-O 3.49Å; Y222-A280 WeakPolarHBondContact OH-CB 3.39Å; Y222-G281 PolarHBondContact OH-N 3.25Å
223	A	95.2	Very high	93.1	Very high	51 Å²	51	55.3 Å²	55.3	42%	0.421	30%	0.303	S	S	.	.	H	α-helix	trans	-60.7	-43.1	176.2	0	0	0	0	0	111.2	V219 L220 A227	V219-A223 WeakPolarHBondContact O-CB 3.2Å; V219-A223 PolarHBondContact O-N 3.43Å; L220-A223 PolarHBondContact O-N 3.11Å; A223-A227 VanDerWaalsContact O-CB 3.3Å; A223-A227 WeakPolarHBondContact O-CB 3.4Å; A223-A227 PolarHBondContact O-N 3.09Å
224	T	93.2	Very high	93.1	Very high	62 Å²	62	58.4 Å²	58.4	38%	0.38	32%	0.315	S	S	.	.	H	α-helix	trans	-63.5	-44.5	173.8	-58.1	0	0	0	0	111.8	L220 S221 Y222 I226 A227 I228	L220-T224 PolarHBondContact O-N 2.79Å; L220-T224 PolarHBondContact O-OG1 2.91Å; S221-T224 PolarHBondContact O-N 3.15Å; Y222-T224 VanDerWaalsContact C-N 3.32Å; Y222-T224 PolarHBondContact O-N 3.43Å; T224-I226 PolarHBondContact O-N 3.32Å; T224-A227 PolarHBondContact O-N 3.01Å; T224-I228 HydrophobicContact CG2-CD1 3.85Å; T224-I228 HydrophobicContact CG2-CG1 4.43Å; T224-I228 VanDerWaalsContact O-CG1 3.29Å; T224-I228 WeakPolarHBondContact O-CG1 3.14Å; T224-I228 PolarHBondContact O-N 2.91Å
225	A	94.4	Very high	92.9	Very high	8 Å²	8	62.3 Å²	62.3	7%	0.066	33%	0.329	C	S	.	.	H	α-helix	trans	-59.6	-47.2	177.4	0	0	0	0	0	111.9	S221 Y222 I228 V229 A285 M288	S221-A225 WeakPolarHBondContact O-CB 3.32Å; S221-A225 PolarHBondContact O-N 3.27Å; Y222-A225 PolarHBondContact O-N 2.75Å; A225-I228 PolarHBondContact O-N 3.47Å; A225-V229 VanDerWaalsContact O-CG2 3.29Å; A225-V229 WeakPolarHBondContact O-CG2 3.29Å; A225-V229 PolarHBondContact O-N 3.04Å; A225-A285 HydrophobicContact CB-CB 4.36Å; A225-M288 HydrophobicContact CB-CG 4.21Å
226	I	94.5	Very high	92.7	Very high	107 Å²	107	58.9 Å²	58.9	55%	0.549	31%	0.31	S	S	.	.	H	α-helix	trans	-63.3	-44.4	178.2	-66.8	165.7	0	0	0	110.8	Y222 T224 I228 V229 V230	Y222-I226 WeakPolarHBondContact O-CB 3.37Å; Y222-I226 VanDerWaalsContact O-CG1 3.27Å; Y222-I226 WeakPolarHBondContact O-CG1 3.37Å; Y222-I226 PolarHBondContact O-N 3.02Å; T224-I226 PolarHBondContact O-N 3.32Å; I226-I228 VanDerWaalsContact C-N 3.34Å; I226-I228 PolarHBondContact O-N 2.98Å; I226-V229 PolarHBondContact O-N 2.97Å; I226-V230 HydrophobicContact CG2-CG2 4.43Å; I226-V230 WeakPolarHBondContact O-CG2 3.48Å; I226-V230 PolarHBondContact O-N 2.66Å
227	A	95	Very high	92.3	Very high	48 Å²	48	53 Å²	53	40%	0.397	29%	0.286	S	S	.	.	H	α-helix	trans	-59.3	-45.2	177.5	0	0	0	0	0	111.6	A223 T224 V230 L231	A223-A227 VanDerWaalsContact O-CB 3.3Å; A223-A227 WeakPolarHBondContact O-CB 3.4Å; A223-A227 PolarHBondContact O-N 3.09Å; T224-A227 PolarHBondContact O-N 3.01Å; A227-V230 PolarHBondContact O-N 3.41Å; A227-L231 WeakPolarHBondContact O-CG 3.33Å; A227-L231 PolarHBondContact O-N 3.45Å
228	I	93.4	Very high	91.9	Very high	31 Å²	31	52.9 Å²	52.9	16%	0.159	30%	0.295	C	S	.	.	H	α-helix	trans	-62	-45.8	176.9	-65.3	166.3	0	0	0	110.5	T224 A225 I226 V230 L231 L232 M288 W292	T224-I228 HydrophobicContact CG2-CD1 3.85Å; T224-I228 HydrophobicContact CG2-CG1 4.43Å; T224-I228 VanDerWaalsContact O-CG1 3.29Å; T224-I228 WeakPolarHBondContact O-CG1 3.14Å; T224-I228 PolarHBondContact O-N 2.91Å; A225-I228 PolarHBondContact O-N 3.47Å; I226-I228 VanDerWaalsContact C-N 3.34Å; I226-I228 PolarHBondContact O-N 2.98Å; I228-V230 VanDerWaalsContact C-N 3.35Å; I228-V230 PolarHBondContact O-N 2.94Å; I228-L231 PolarHBondContact O-N 3.4Å; I228-L232 HydrophobicContact CG2-CD1 3.78Å; I228-L232 HydrophobicContact CG2-CG 4.07Å; I228-L232 WeakPolarHBondContact O-CB 3.46Å; I228-L232 VanDerWaalsContact O-CG 3.23Å; I228-L232 WeakPolarHBondContact O-CG 3.47Å; I228-L232 PolarHBondContact O-N 3.2Å; I228-M288 HydrophobicContact CB-CB 3.99Å; I228-M288 HydrophobicContact CD1-CB 4.21Å; I228-M288 HydrophobicContact CG2-CB 3.76Å; I228-W292 HydrophobicContact CG2-CB 4.36Å
229	V	94.2	Very high	91.6	Very high	13 Å²	13	55.3 Å²	55.3	8%	0.079	31%	0.307	C	S	.	.	H	α-helix	trans	-56.3	-47.6	177.6	171.3	0	0	0	0	111.8	A225 I226 L231 L232 Y233 I249 L253 M288	A225-V229 VanDerWaalsContact O-CG2 3.29Å; A225-V229 WeakPolarHBondContact O-CG2 3.29Å; A225-V229 PolarHBondContact O-N 3.04Å; I226-V229 PolarHBondContact O-N 2.97Å; V229-L231 PolarHBondContact O-N 3.37Å; V229-L232 PolarHBondContact O-N 2.98Å; V229-Y233 HydrophobicContact CG1-CD2 3.91Å; V229-Y233 HydrophobicContact CG1-CE2 3.8Å; V229-Y233 WeakPolarHBondContact O-CD2 3.46Å; V229-Y233 PolarHBondContact O-N 3.44Å; V229-Y233 VanDerWaalsContact O-N 3.08Å; V229-I249 HydrophobicContact CG1-CG2 4.41Å; V229-L253 HydrophobicContact CG1-CD1 4.42Å; V229-L253 HydrophobicContact CG1-CD2 4.23Å; V229-L253 HydrophobicContact CG2-CD1 4.2Å; V229-M288 HydrophobicContact CG2-CE 4.15Å; V229-M288 HydrophobicContact CG2-CG 3.89Å; V229-M288 HydrophobicContact CG2-SD 3.25Å; V229-M288 WeakPolarHBondContact CG2-SD 3.16Å
230	V	94.3	Very high	91.2	Very high	77 Å²	77	55.2 Å²	55.2	47%	0.467	31%	0.308	S	S	.	.	H	α-helix	trans	-61.7	-46.1	179.7	172.4	0	0	0	0	110.7	I226 A227 I228 L232 Y233 I234	I226-V230 HydrophobicContact CG2-CG2 4.43Å; I226-V230 WeakPolarHBondContact O-CG2 3.48Å; I226-V230 PolarHBondContact O-N 2.66Å; A227-V230 PolarHBondContact O-N 3.41Å; I228-V230 VanDerWaalsContact C-N 3.35Å; I228-V230 PolarHBondContact O-N 2.94Å; V230-L232 VanDerWaalsContact C-N 3.3Å; V230-L232 PolarHBondContact O-N 3.01Å; V230-Y233 PolarHBondContact O-N 2.94Å; V230-I234 HydrophobicContact CG1-CD1 3.81Å; V230-I234 WeakPolarHBondContact O-CG1 3.35Å; V230-I234 PolarHBondContact O-N 3.49Å; V230-I234 VanDerWaalsContact O-N 3.1Å
231	L	92.7	Very high	90.8	Very high	86 Å²	86	55.5 Å²	55.5	45%	0.45	31%	0.314	S	S	.	.	H	α-helix	trans	-62.8	-37.5	177.1	-65.8	169.1	0	0	0	111.7	A227 I228 V229 I234 Y235	A227-L231 WeakPolarHBondContact O-CG 3.33Å; A227-L231 PolarHBondContact O-N 3.45Å; I228-L231 PolarHBondContact O-N 3.4Å; V229-L231 PolarHBondContact O-N 3.37Å; L231-I234 PolarHBondContact O-N 3.49Å; L231-Y235 HydrophobicContact CB-CD2 4.29Å; L231-Y235 HydrophobicContact CD2-CD2 4.37Å; L231-Y235 HydrophobicContact CD2-CE2 3.77Å; L231-Y235 VanDerWaalsContact O-CD2 3.24Å; L231-Y235 WeakPolarHBondContact O-CD2 3.25Å; L231-Y235 PolarHBondContact O-N 3.22Å
232	L	92	Very high	90.5	Very high	3 Å²	3	55.2 Å²	55.2	2%	0.016	31%	0.312	C	S	.	.	H	α-helix	trans	-64.6	-43.3	177.9	-72	174.4	0	0	0	112.5	I228 V229 V230 F236 G237 I249 T291 W292	I228-L232 HydrophobicContact CG2-CD1 3.78Å; I228-L232 HydrophobicContact CG2-CG 4.07Å; I228-L232 WeakPolarHBondContact O-CB 3.46Å; I228-L232 VanDerWaalsContact O-CG 3.23Å; I228-L232 WeakPolarHBondContact O-CG 3.47Å; I228-L232 PolarHBondContact O-N 3.2Å; V229-L232 PolarHBondContact O-N 2.98Å; V230-L232 VanDerWaalsContact C-N 3.3Å; V230-L232 PolarHBondContact O-N 3.01Å; L232-F236 HydrophobicContact CD2-CD2 3.69Å; L232-F236 HydrophobicContact CD2-CE2 4.03Å; L232-F236 HydrophobicContact CD2-CG 4.47Å; L232-F236 WeakPolarHBondContact O-CA 3.05Å; L232-F236 WeakPolarHBondContact O-CB 3.39Å; L232-F236 PolarHBondContact O-N 3.04Å; L232-G237 PolarHBondContact O-N 3.46Å; L232-I249 HydrophobicContact CB-CD1 3.69Å; L232-I249 HydrophobicContact CB-CG1 4.01Å; L232-I249 HydrophobicContact CB-CG2 4.4Å; L232-I249 HydrophobicContact CD1-CG1 4.33Å; L232-T291 HydrophobicContact CD1-CG2 3.87Å; L232-W292 HydrophobicContact CD1-CB 4.44Å; L232-W292 HydrophobicContact CD2-CB 3.81Å; L232-W292 HydrophobicContact CD2-CG 4.2Å
233	Y	92	Very high	90.3	Very high	82 Å²	82	57.5 Å²	57.5	32%	0.322	33%	0.327	S	S	.	.	H	α-helix	trans	-64.6	-39	174.8	-81.6	-66.7	0	0	0	112.5	V229 V230 G237 S238 I249 S250	V229-Y233 HydrophobicContact CG1-CD2 3.91Å; V229-Y233 HydrophobicContact CG1-CE2 3.8Å; V229-Y233 WeakPolarHBondContact O-CD2 3.46Å; V229-Y233 PolarHBondContact O-N 3.44Å; V229-Y233 VanDerWaalsContact O-N 3.08Å; V230-Y233 PolarHBondContact O-N 2.94Å; Y233-G237 CarbonylContact O-C 3.53Å; Y233-G237 VanDerWaalsContact O-CA 3.29Å; Y233-G237 WeakPolarHBondContact O-CA 3.03Å; Y233-G237 PolarHBondContact O-N 3.29Å; Y233-S238 PolarHBondContact O-N 3.41Å; Y233-I249 HydrophobicContact CD2-CG2 3.9Å; Y233-I249 HydrophobicContact CE1-CB 4.43Å; Y233-I249 HydrophobicContact CE1-CG2 4.12Å; Y233-I249 HydrophobicContact CE2-CG2 3.47Å; Y233-I249 VanDerWaalsContact CE2-CG2 3.47Å; Y233-I249 HydrophobicContact CG-CG2 4.4Å; Y233-S250 PolarHBondContact OH-OG 3.24Å
234	I	90.1	Very high	90	Very high	89 Å²	89	58.3 Å²	58.3	46%	0.456	32%	0.324	S	S	.	.	H	α-helix	trans	-68.4	-47.3	179.6	-66.8	169.4	0	0	0	111.3	V230 L231 S238	V230-I234 HydrophobicContact CG1-CD1 3.81Å; V230-I234 WeakPolarHBondContact O-CG1 3.35Å; V230-I234 PolarHBondContact O-N 3.49Å; V230-I234 VanDerWaalsContact O-N 3.1Å; L231-I234 PolarHBondContact O-N 3.49Å; I234-S238 WeakPolarHBondContact O-CB 3.43Å; I234-S238 PolarHBondContact O-OG 3Å
235	Y	87	Confident	89.9	Confident	103 Å²	103	55.4 Å²	55.4	40%	0.404	31%	0.306	S	S	.	.	H	α-helix	trans	-91.9	-39.4	-171.7	-68.3	-67	0	0	0	114.1	L231 P305 I310	L231-Y235 HydrophobicContact CB-CD2 4.29Å; L231-Y235 HydrophobicContact CD2-CD2 4.37Å; L231-Y235 HydrophobicContact CD2-CE2 3.77Å; L231-Y235 VanDerWaalsContact O-CD2 3.24Å; L231-Y235 WeakPolarHBondContact O-CD2 3.25Å; L231-Y235 PolarHBondContact O-N 3.22Å; Y235-P305 WeakPolarHBondContact O-CG 3.33Å; Y235-I310 HydrophobicContact CD1-CD1 3.6Å; Y235-I310 HydrophobicContact CD1-CG1 4.33Å; Y235-I310 HydrophobicContact CE1-CD1 3.83Å; Y235-I310 HydrophobicContact CE1-CG1 4.41Å; Y235-I310 HydrophobicContact CE1-CG2 3.96Å; Y235-I310 HydrophobicContact CG-CD1 4.5Å
236	F	86.8	Confident	89.8	Confident	19 Å²	19	58.9 Å²	58.9	8%	0.083	32%	0.318	C	S	.	.	H	α-helix	trans	-105.7	-7.6	-174	-63.1	-90.1	0	0	0	113.3	L232 N245 W292 M295 C303	L232-F236 HydrophobicContact CD2-CD2 3.69Å; L232-F236 HydrophobicContact CD2-CE2 4.03Å; L232-F236 HydrophobicContact CD2-CG 4.47Å; L232-F236 WeakPolarHBondContact O-CA 3.05Å; L232-F236 WeakPolarHBondContact O-CB 3.39Å; L232-F236 PolarHBondContact O-N 3.04Å; F236-N245 WeakPolarHBondContact O-CB 3.34Å; F236-N245 PolarHBondContact O-ND2 3.35Å; F236-W292 AromaticContact CE2-CD1 3.83Å; F236-M295 HydrophobicContact CB-CB 4.22Å; F236-M295 HydrophobicContact CB-CG 4.47Å; F236-M295 HydrophobicContact CD1-CB 3.51Å; F236-M295 HydrophobicContact CD2-CB 4.43Å; F236-M295 HydrophobicContact CE1-CB 3.9Å; F236-M295 HydrophobicContact CG-CB 3.8Å; F236-M295 HydrophobicContact CG-CG 4.49Å; F236-M295 HydrophobicContact CZ-CB 4.49Å; F236-C303 VanDerWaalsContact CD1-O 3.28Å; F236-C303 WeakPolarHBondContact CD1-O 3.46Å
237	G	84.4	Confident	89.7	Confident	4 Å²	4	57.2 Å²	57.2	4%	0.041	31%	0.313	C	S	.	.	S	Bend	trans	-123.2	5.6	-176.7	0	0	0	0	0	114.9	L232 Y233 R246	L232-G237 PolarHBondContact O-N 3.46Å; Y233-G237 CarbonylContact O-C 3.53Å; Y233-G237 VanDerWaalsContact O-CA 3.29Å; Y233-G237 WeakPolarHBondContact O-CA 3.03Å; Y233-G237 PolarHBondContact O-N 3.29Å; G237-R246 PolarHBondContact O-NE 2.89Å; G237-R246 PolarHBondContact O-NH2 3.31Å
238	S	83.3	Confident	89.7	Confident	82 Å²	82	55.3 Å²	55.3	57%	0.573	30%	0.295	S	S	*	.	S	Bend	trans	-68.3	-41	-177.5	-84	0	0	0	0	113.2	Y233 I234 R246	Y233-S238 PolarHBondContact O-N 3.41Å; I234-S238 WeakPolarHBondContact O-CB 3.43Å; I234-S238 PolarHBondContact O-OG 3Å; S238-R246 PolarHBondContact O-NH2 3.37Å
239	D	85.3	Confident	89.8	Confident	60 Å²	60	53.8 Å²	53.8	32%	0.321	29%	0.288	S	S	.	.	S	Bend	trans	-76.2	136	-177.3	-164.1	-69.9	0	0	0	111.8	T241 C242 R246 V302	D239-T241 PolarHBondContact O-N 2.86Å; D239-T241 VanDerWaalsContact OD1-CB 3.3Å; D239-T241 WeakPolarHBondContact OD1-CB 2.98Å; D239-T241 WeakPolarHBondContact OD1-CG2 3.25Å; D239-T241 PolarHBondContact OD1-N 3.3Å; D239-T241 PolarHBondContact OD1-OG1 3.37Å; D239-C242 PolarHBondContact O-N 3.1Å; D239-R246 PolarHBondContact O-NH2 3.15Å; D239-V302 HydrophobicContact CB-CG1 4.08Å
240	P	83.9	Confident	89.8	Confident	91 Å²	91	55.1 Å²	55.1	59%	0.591	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.7	-19.4	177.3	26.3	-36.4	0	0	0	114.6	C242 N243	P240-C242 VanDerWaalsContact C-N 3.34Å; P240-N243 PolarHBondContact O-ND2 3.19Å; P240-N243 PolarHBondContact O-OD1 3.43Å
241	T	87.9	Confident	89.8	Confident	91 Å²	91	54.4 Å²	54.4	56%	0.558	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	-24.1	176.9	60	0	0	0	0	112.6	D239 N243	D239-T241 PolarHBondContact O-N 2.86Å; D239-T241 VanDerWaalsContact OD1-CB 3.3Å; D239-T241 WeakPolarHBondContact OD1-CB 2.98Å; D239-T241 WeakPolarHBondContact OD1-CG2 3.25Å; D239-T241 PolarHBondContact OD1-N 3.3Å; D239-T241 PolarHBondContact OD1-OG1 3.37Å; T241-N243 PolarHBondContact O-N 2.93Å
242	C	86.8	Confident	90	Very high	3 Å²	3	50.3 Å²	50.3	2%	0.02	27%	0.269	C	S	.	.			trans	-82.2	48.4	-175.7	-55	0	0	0	0	113.5	D239 P240 L244 N245 R246 C303	D239-C242 PolarHBondContact O-N 3.1Å; P240-C242 VanDerWaalsContact C-N 3.34Å; C242-L244 VanDerWaalsContact C-N 3.3Å; C242-L244 PolarHBondContact O-N 3.45Å; C242-N245 PolarHBondContact O-N 3.26Å; C242-R246 WeakPolarHBondContact O-CG 3.48Å; C242-R246 PolarHBondContact O-N 3.24Å; C242-C303 WeakPolarHBondContact CA-SG 3.22Å; C242-C303 HydrophobicContact CB-CB 3.84Å; C242-C303 WeakPolarHBondContact CB-SG 3.43Å; C242-C303 WeakPolarHBondContact SG-CA 3.36Å; C242-C303 WeakPolarHBondContact SG-CB 3.2Å; C242-C303 CovalentContact SG-SG 2.03Å; C242-C303 PolarHBondContact SG-SG 3.41Å
243	N	89.8	Confident	90.1	Very high	97 Å²	97	52.9 Å²	52.9	52%	0.519	28%	0.282	S	S	.	.	H	α-helix	trans	-62.3	-37.6	-178.6	-71.5	-41.6	0	0	0	112.2	P240 T241 N245 R246 T247	P240-N243 PolarHBondContact O-ND2 3.19Å; P240-N243 PolarHBondContact O-OD1 3.43Å; T241-N243 PolarHBondContact O-N 2.93Å; N243-N245 PolarHBondContact O-N 3.35Å; N243-R246 PolarHBondContact O-N 2.03Å; N243-T247 PolarHBondContact O-N 3.31Å; N243-T247 PolarHBondContact O-OG1 3.16Å
244	L	89.9	Confident	90.2	Very high	68 Å²	68	54.2 Å²	54.2	36%	0.356	29%	0.294	S	S	.	.	H	α-helix	trans	-60.1	-49.1	-179.8	-173.8	66.3	0	0	0	111.7	C242 R246 T247 F248 M434	C242-L244 VanDerWaalsContact C-N 3.3Å; C242-L244 PolarHBondContact O-N 3.45Å; L244-R246 PolarHBondContact O-N 3.21Å; L244-T247 PolarHBondContact O-N 3.01Å; L244-F248 HydrophobicContact CD1-CD2 4.3Å; L244-F248 HydrophobicContact CD1-CE1 4.18Å; L244-F248 HydrophobicContact CD1-CE2 3.63Å; L244-F248 HydrophobicContact CD1-CZ 3.55Å; L244-F248 HydrophobicContact CD2-CE2 3.84Å; L244-F248 HydrophobicContact CD2-CZ 4.36Å; L244-F248 HydrophobicContact CG-CD2 3.94Å; L244-F248 HydrophobicContact CG-CE2 3.44Å; L244-F248 VanDerWaalsContact CG-CE2 3.44Å; L244-F248 HydrophobicContact CG-CZ 3.93Å; L244-F248 WeakPolarHBondContact O-CD2 3.5Å; L244-F248 WeakPolarHBondContact O-CG 3.29Å; L244-F248 PolarHBondContact O-N 3.38Å; L244-M434 HydrophobicContact CD2-CE 3.73Å
245	N	90.9	Very high	90.4	Very high	1 Å²	1	52.5 Å²	52.5	1%	0.005	29%	0.285	C	S	.	.	H	α-helix	trans	-60.8	-46	178.1	-68.7	4.2	0	0	0	111.2	F236 C242 N243 T247 F248 I249 M295 C303	F236-N245 WeakPolarHBondContact O-CB 3.34Å; F236-N245 PolarHBondContact O-ND2 3.35Å; C242-N245 PolarHBondContact O-N 3.26Å; N243-N245 PolarHBondContact O-N 3.35Å; N245-T247 VanDerWaalsContact C-N 3.3Å; N245-T247 PolarHBondContact O-N 3.45Å; N245-F248 PolarHBondContact O-N 2.91Å; N245-I249 WeakPolarHBondContact O-CD1 3.49Å; N245-I249 WeakPolarHBondContact O-CG1 3.47Å; N245-I249 PolarHBondContact O-N 2.88Å; N245-M295 HydrophobicContact CB-SD 3.68Å; N245-M295 PolarHBondContact OD1-SD 3.48Å; N245-C303 PolarHBondContact ND2-O 2.89Å
246	R	91.7	Very high	90.7	Very high	81 Å²	81	48 Å²	48	31%	0.306	27%	0.269	S	S	.	.	H	α-helix	trans	-57.9	-42.9	176	-70.6	177	177.6	-179.7	0.1	111.8	G237 S238 D239 C242 N243 L244 S250	G237-R246 PolarHBondContact O-NE 2.89Å; G237-R246 PolarHBondContact O-NH2 3.31Å; S238-R246 PolarHBondContact O-NH2 3.37Å; D239-R246 PolarHBondContact O-NH2 3.15Å; C242-R246 WeakPolarHBondContact O-CG 3.48Å; C242-R246 PolarHBondContact O-N 3.24Å; N243-R246 PolarHBondContact O-N 2.03Å; L244-R246 PolarHBondContact O-N 3.21Å; R246-S250 WeakPolarHBondContact O-CB 3.32Å; R246-S250 PolarHBondContact O-N 2.96Å; R246-S250 PolarHBondContact O-OG 3.45Å
247	T	93.1	Very high	91	Very high	73 Å²	73	51.8 Å²	51.8	45%	0.448	29%	0.289	S	S	.	.	H	α-helix	trans	-64.1	-46.8	177.8	-61.3	0	0	0	0	111.4	N243 L244 N245 S250 I251	N243-T247 PolarHBondContact O-N 3.31Å; N243-T247 PolarHBondContact O-OG1 3.16Å; L244-T247 PolarHBondContact O-N 3.01Å; N245-T247 VanDerWaalsContact C-N 3.3Å; N245-T247 PolarHBondContact O-N 3.45Å; T247-S250 PolarHBondContact O-N 3.41Å; T247-I251 HydrophobicContact CG2-CD1 3.7Å; T247-I251 HydrophobicContact CG2-CG1 4.34Å; T247-I251 WeakPolarHBondContact O-CG1 3.26Å; T247-I251 PolarHBondContact O-N 3.23Å
248	F	94.4	Very high	91.4	Very high	7 Å²	7	53.9 Å²	53.9	3%	0.031	31%	0.306	C	S	.	.	H	α-helix	trans	-63	-44.4	179.1	-69.5	-35.4	0	0	0	113.2	L244 N245 S250 I251 N252 M295 V437 W438 I441	L244-F248 HydrophobicContact CD1-CD2 4.3Å; L244-F248 HydrophobicContact CD1-CE1 4.18Å; L244-F248 HydrophobicContact CD1-CE2 3.63Å; L244-F248 HydrophobicContact CD1-CZ 3.55Å; L244-F248 HydrophobicContact CD2-CE2 3.84Å; L244-F248 HydrophobicContact CD2-CZ 4.36Å; L244-F248 HydrophobicContact CG-CD2 3.94Å; L244-F248 HydrophobicContact CG-CE2 3.44Å; L244-F248 VanDerWaalsContact CG-CE2 3.44Å; L244-F248 HydrophobicContact CG-CZ 3.93Å; L244-F248 WeakPolarHBondContact O-CD2 3.5Å; L244-F248 WeakPolarHBondContact O-CG 3.29Å; L244-F248 PolarHBondContact O-N 3.38Å; N245-F248 PolarHBondContact O-N 2.91Å; F248-S250 VanDerWaalsContact C-N 3.31Å; F248-S250 PolarHBondContact O-N 3.39Å; F248-I251 PolarHBondContact O-N 2.88Å; F248-N252 PolarHBondContact O-N 3.22Å; F248-M295 HydrophobicContact CD2-CE 3.73Å; F248-M295 HydrophobicContact CD2-SD 4.31Å; F248-M295 HydrophobicContact CE2-CE 4.42Å; F248-V437 HydrophobicContact CE2-CG1 4.22Å; F248-W438 HydrophobicContact CE1-CH2 4.14Å; F248-W438 HydrophobicContact CE1-CZ3 4.25Å; F248-W438 AromaticContact CZ-CH2 3.95Å; F248-W438 HydrophobicContact CZ-CH2 3.95Å; F248-W438 HydrophobicContact CZ-CZ2 4.07Å; F248-W438 HydrophobicContact CZ-CZ3 4.22Å; F248-I441 HydrophobicContact CB-CD1 4.08Å; F248-I441 HydrophobicContact CD1-CG1 4.48Å; F248-I441 HydrophobicContact CD1-CG2 3.93Å; F248-I441 HydrophobicContact CD2-CD1 4.41Å; F248-I441 HydrophobicContact CD2-CG1 4.22Å; F248-I441 HydrophobicContact CE1-CG2 4Å; F248-I441 HydrophobicContact CE2-CG1 4.36Å; F248-I441 HydrophobicContact CG-CD1 4.17Å; F248-I441 HydrophobicContact CG-CG1 4.25Å; F248-I441 HydrophobicContact CG-CG2 4.48Å
249	I	94.6	Very high	91.7	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-59.6	-45.6	175.7	-62.4	159.7	0	0	0	110	V229 L232 Y233 N245 N252 L253 T291	V229-I249 HydrophobicContact CG1-CG2 4.41Å; L232-I249 HydrophobicContact CB-CD1 3.69Å; L232-I249 HydrophobicContact CB-CG1 4.01Å; L232-I249 HydrophobicContact CB-CG2 4.4Å; L232-I249 HydrophobicContact CD1-CG1 4.33Å; Y233-I249 HydrophobicContact CD2-CG2 3.9Å; Y233-I249 HydrophobicContact CE1-CB 4.43Å; Y233-I249 HydrophobicContact CE1-CG2 4.12Å; Y233-I249 HydrophobicContact CE2-CG2 3.47Å; Y233-I249 VanDerWaalsContact CE2-CG2 3.47Å; Y233-I249 HydrophobicContact CG-CG2 4.4Å; N245-I249 WeakPolarHBondContact O-CD1 3.49Å; N245-I249 WeakPolarHBondContact O-CG1 3.47Å; N245-I249 PolarHBondContact O-N 2.88Å; I249-N252 PolarHBondContact O-N 3.3Å; I249-L253 WeakPolarHBondContact O-CB 3.27Å; I249-L253 PolarHBondContact O-N 2.91Å; I249-T291 HydrophobicContact CG1-CG2 4.14Å
250	S	94.9	Very high	92	Very high	40 Å²	40	48.4 Å²	48.4	28%	0.28	27%	0.272	S	S	.	.	H	α-helix	trans	-65.4	-43.5	-178.3	-53.8	0	0	0	0	112.4	Y233 R246 T247 F248 L253 I254	Y233-S250 PolarHBondContact OH-OG 3.24Å; R246-S250 WeakPolarHBondContact O-CB 3.32Å; R246-S250 PolarHBondContact O-N 2.96Å; R246-S250 PolarHBondContact O-OG 3.45Å; T247-S250 PolarHBondContact O-N 3.41Å; F248-S250 VanDerWaalsContact C-N 3.31Å; F248-S250 PolarHBondContact O-N 3.39Å; S250-L253 PolarHBondContact O-N 2.59Å; S250-I254 VanDerWaalsContact O-CG1 3.27Å; S250-I254 WeakPolarHBondContact O-CG1 3.38Å; S250-I254 PolarHBondContact O-N 2.82Å
251	I	95.4	Very high	92.3	Very high	62 Å²	62	48.2 Å²	48.2	32%	0.318	27%	0.269	S	S	.	.	H	α-helix	trans	-62.9	-49	177.9	-70.3	170.6	0	0	0	110.5	T247 F248 L253 I254 L255 W445	T247-I251 HydrophobicContact CG2-CD1 3.7Å; T247-I251 HydrophobicContact CG2-CG1 4.34Å; T247-I251 WeakPolarHBondContact O-CG1 3.26Å; T247-I251 PolarHBondContact O-N 3.23Å; F248-I251 PolarHBondContact O-N 2.88Å; I251-L253 VanDerWaalsContact C-N 3.29Å; I251-L253 PolarHBondContact O-N 2.98Å; I251-I254 PolarHBondContact O-N 2.79Å; I251-L255 HydrophobicContact CG2-CD1 4Å; I251-L255 HydrophobicContact CG2-CG 4.38Å; I251-L255 WeakPolarHBondContact O-CG 3.38Å; I251-L255 PolarHBondContact O-N 2.72Å; I251-W445 HydrophobicContact CG2-CZ2 4.44Å
252	N	95.4	Very high	92.2	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-65.2	-34.4	-179.7	-78.9	-20	0	0	0	111.9	F248 I249 L255 C256 I287 M288 T291 S444 W445	F248-N252 PolarHBondContact O-N 3.22Å; I249-N252 PolarHBondContact O-N 3.3Å; N252-L255 PolarHBondContact O-N 3.38Å; N252-C256 PolarHBondContact O-N 3.18Å; N252-C256 PolarHBondContact O-SG 3.26Å; N252-I287 HydrophobicContact CB-CG2 3.92Å; N252-M288 VanDerWaalsContact C-CE 3.5Å; N252-M288 HydrophobicContact CB-CE 3.83Å; N252-M288 WeakPolarHBondContact O-CE 3.15Å; N252-T291 PolarHBondContact ND2-OG1 3.08Å; N252-S444 PolarHBondContact ND2-OG 2.95Å; N252-S444 PolarHBondContact OD1-OG 3.41Å; N252-S444 VanDerWaalsContact OD1-OG 3.06Å; N252-W445 VanDerWaalsContact OD1-CD1 3.25Å; N252-W445 PolarHBondContact OD1-NE1 3.35Å
253	L	94.7	Very high	92.2	Very high	57 Å²	57	45.6 Å²	45.6	30%	0.298	25%	0.253	S	S	.	.	H	α-helix	trans	-62.4	-47.2	172.6	177.2	62.1	0	0	0	111.7	V229 I249 S250 I251 L255 C256 I257	V229-L253 HydrophobicContact CG1-CD1 4.42Å; V229-L253 HydrophobicContact CG1-CD2 4.23Å; V229-L253 HydrophobicContact CG2-CD1 4.2Å; I249-L253 WeakPolarHBondContact O-CB 3.27Å; I249-L253 PolarHBondContact O-N 2.91Å; S250-L253 PolarHBondContact O-N 2.59Å; I251-L253 VanDerWaalsContact C-N 3.29Å; I251-L253 PolarHBondContact O-N 2.98Å; L253-L255 VanDerWaalsContact C-N 3.32Å; L253-L255 PolarHBondContact O-N 3.01Å; L253-C256 PolarHBondContact O-N 2.96Å; L253-I257 HydrophobicContact CD1-CD1 4.19Å; L253-I257 HydrophobicContact CG-CD1 4.13Å; L253-I257 WeakPolarHBondContact O-CG1 3.45Å; L253-I257 PolarHBondContact O-N 3.37Å
254	I	95	Very high	92.1	Very high	111 Å²	111	44.5 Å²	44.5	57%	0.569	25%	0.249	S	C	*	.	H	α-helix	trans	-60.8	-43.2	177.1	-68.1	164.3	0	0	0	110.6	S250 I251 I257 A258	S250-I254 VanDerWaalsContact O-CG1 3.27Å; S250-I254 WeakPolarHBondContact O-CG1 3.38Å; S250-I254 PolarHBondContact O-N 2.82Å; I251-I254 PolarHBondContact O-N 2.79Å; I254-I257 PolarHBondContact O-N 3.5Å; I254-A258 WeakPolarHBondContact O-CB 3.29Å; I254-A258 PolarHBondContact O-N 3Å
255	L	93.1	Very high	91.9	Very high	52 Å²	52	45 Å²	45	27%	0.272	25%	0.252	S	S	.	.	H	α-helix	trans	-61.2	-45	176.7	-71.9	174.2	0	0	0	111.9	I251 N252 L253 I257 A258 V259 W445 A448	I251-L255 HydrophobicContact CG2-CD1 4Å; I251-L255 HydrophobicContact CG2-CG 4.38Å; I251-L255 WeakPolarHBondContact O-CG 3.38Å; I251-L255 PolarHBondContact O-N 2.72Å; N252-L255 PolarHBondContact O-N 3.38Å; L253-L255 VanDerWaalsContact C-N 3.32Å; L253-L255 PolarHBondContact O-N 3.01Å; L255-I257 VanDerWaalsContact C-N 3.33Å; L255-I257 PolarHBondContact O-N 2.91Å; L255-A258 PolarHBondContact O-N 3.24Å; L255-V259 WeakPolarHBondContact O-CG2 3.4Å; L255-V259 PolarHBondContact O-N 3.07Å; L255-W445 VanDerWaalsContact CD1-CD1 3.45Å; L255-W445 HydrophobicContact CD1-CG 4.26Å; L255-A448 HydrophobicContact CB-CB 4.26Å; L255-A448 HydrophobicContact CD1-CB 4.39Å
256	C	93.7	Very high	91.5	Very high	10 Å²	10	49 Å²	49	7%	0.068	28%	0.278	C	S	.	.	H	α-helix	trans	-60.2	-42.2	176	-71.2	0	0	0	0	112	N252 L253 S260 M288	N252-C256 PolarHBondContact O-N 3.18Å; N252-C256 PolarHBondContact O-SG 3.26Å; L253-C256 PolarHBondContact O-N 2.96Å; C256-S260 WeakPolarHBondContact O-CB 3.3Å; C256-S260 PolarHBondContact O-N 3.49Å; C256-S260 PolarHBondContact O-OG 3.38Å; C256-M288 HydrophobicContact CB-CE 4.4Å; C256-M288 WeakPolarHBondContact SG-CE 3.42Å
257	I	93.1	Very high	91	Very high	98 Å²	98	48.5 Å²	48.5	50%	0.503	29%	0.287	S	S	.	.	H	α-helix	trans	-64.4	-48.1	176.2	-66.1	166.7	0	0	0	110.3	L253 I254 L255 V259 S260 V261	L253-I257 HydrophobicContact CD1-CD1 4.19Å; L253-I257 HydrophobicContact CG-CD1 4.13Å; L253-I257 WeakPolarHBondContact O-CG1 3.45Å; L253-I257 PolarHBondContact O-N 3.37Å; I254-I257 PolarHBondContact O-N 3.5Å; L255-I257 VanDerWaalsContact C-N 3.33Å; L255-I257 PolarHBondContact O-N 2.91Å; I257-V259 PolarHBondContact O-N 3.24Å; I257-S260 PolarHBondContact O-N 3.32Å; I257-V261 HydrophobicContact CG2-CG2 4.43Å; I257-V261 WeakPolarHBondContact O-CG2 3.49Å; I257-V261 PolarHBondContact O-N 3.44Å
258	A	91.9	Very high	90.4	Very high	47 Å²	47	45.1 Å²	45.1	39%	0.388	27%	0.267	S	S	.	.	H	α-helix	trans	-59.3	-47	-178.9	0	0	0	0	0	112.1	I254 L255 S260 V261 V262	I254-A258 WeakPolarHBondContact O-CB 3.29Å; I254-A258 PolarHBondContact O-N 3Å; L255-A258 PolarHBondContact O-N 3.24Å; A258-S260 VanDerWaalsContact C-N 3.33Å; A258-S260 PolarHBondContact O-N 3.3Å; A258-V261 PolarHBondContact O-N 3.08Å; A258-V262 WeakPolarHBondContact O-CG2 3.36Å; A258-V262 PolarHBondContact O-N 3.07Å
259	V	89.8	Confident	89.8	Confident	11 Å²	11	48.8 Å²	48.8	7%	0.067	28%	0.284	C	S	.	.	H	α-helix	trans	-66.2	-36.8	178.7	176.7	0	0	0	0	111.5	L255 I257 V262 A263 A448 L451	L255-V259 WeakPolarHBondContact O-CG2 3.4Å; L255-V259 PolarHBondContact O-N 3.07Å; I257-V259 PolarHBondContact O-N 3.24Å; V259-V262 PolarHBondContact O-N 2.5Å; V259-A263 WeakPolarHBondContact O-CB 3.34Å; V259-A263 PolarHBondContact O-N 2.87Å; V259-A448 HydrophobicContact CG2-CB 4.28Å; V259-L451 HydrophobicContact CG1-CB 4.23Å; V259-L451 HydrophobicContact CG1-CD2 3.3Å; V259-L451 HydrophobicContact CG1-CG 3.57Å
260	S	91.1	Very high	89	Confident	16 Å²	16	58.7 Å²	58.7	11%	0.112	32%	0.321	C	S	.	.	H	α-helix	trans	-64.3	-40.2	174.5	-57.2	0	0	0	0	112.3	Y222 C256 I257 A258 A263 V264	Y222-S260 PolarHBondContact OH-OG 3.28Å; Y222-S260 VanDerWaalsContact OH-OG 3.09Å; C256-S260 WeakPolarHBondContact O-CB 3.3Å; C256-S260 PolarHBondContact O-N 3.49Å; C256-S260 PolarHBondContact O-OG 3.38Å; I257-S260 PolarHBondContact O-N 3.32Å; A258-S260 VanDerWaalsContact C-N 3.33Å; A258-S260 PolarHBondContact O-N 3.3Å; S260-A263 PolarHBondContact O-N 3.25Å; S260-V264 WeakPolarHBondContact O-CG2 3.36Å; S260-V264 PolarHBondContact O-N 3.28Å
261	V	90.2	Very high	88	Confident	87 Å²	87	63.6 Å²	63.6	53%	0.527	33%	0.334	S	S	.	.	H	α-helix	trans	-63.6	-46.7	174.1	171.4	0	0	0	0	110.3	I257 A258 A263 V264 L265	I257-V261 HydrophobicContact CG2-CG2 4.43Å; I257-V261 WeakPolarHBondContact O-CG2 3.49Å; I257-V261 PolarHBondContact O-N 3.44Å; A258-V261 PolarHBondContact O-N 3.08Å; V261-A263 VanDerWaalsContact C-N 3.3Å; V261-A263 PolarHBondContact O-N 3.41Å; V261-V264 PolarHBondContact O-N 2.85Å; V261-V264 VanDerWaalsContact O-N 3.09Å; V261-L265 PolarHBondContact O-N 3.04Å
262	V	87.4	Confident	86.9	Confident	38 Å²	38	61.5 Å²	61.5	23%	0.23	32%	0.323	C	S	.	.	H	α-helix	trans	-59.2	-41.7	179	172	0	0	0	0	111.5	A258 V259 V264 L265 V268 I455	A258-V262 WeakPolarHBondContact O-CG2 3.36Å; A258-V262 PolarHBondContact O-N 3.07Å; V259-V262 PolarHBondContact O-N 2.5Å; V262-V264 PolarHBondContact O-N 3.49Å; V262-L265 HydrophobicContact CB-CD1 4.44Å; V262-L265 HydrophobicContact CG2-CD1 4.31Å; V262-L265 WeakPolarHBondContact O-CB 3.39Å; V262-L265 PolarHBondContact O-N 3.15Å; V262-V268 HydrophobicContact CG1-CG2 4.35Å; V262-V268 WeakPolarHBondContact O-CG2 3.47Å; V262-I455 HydrophobicContact CG1-CG2 3.86Å
263	A	86.2	Confident	85.7	Confident	2 Å²	2	66.6 Å²	66.6	2%	0.017	36%	0.357	C	S	.	.	H	α-helix	trans	-63.6	-21.9	178	0	0	0	0	0	114.2	V259 S260 V261 A280 I455	V259-A263 WeakPolarHBondContact O-CB 3.34Å; V259-A263 PolarHBondContact O-N 2.87Å; S260-A263 PolarHBondContact O-N 3.25Å; V261-A263 VanDerWaalsContact C-N 3.3Å; V261-A263 PolarHBondContact O-N 3.41Å; A263-A280 HydrophobicContact CB-CB 3.96Å; A263-I455 HydrophobicContact CB-CD1 4.19Å
264	V	86.8	Confident	84.5	Confident	73 Å²	73	66.8 Å²	66.8	44%	0.442	36%	0.355	S	S	.	.	H	α-helix	trans	-99.6	-9	-179.7	-179.2	0	0	0	0	112.2	S260 V261 V262 L277	S260-V264 WeakPolarHBondContact O-CG2 3.36Å; S260-V264 PolarHBondContact O-N 3.28Å; V261-V264 PolarHBondContact O-N 2.85Å; V261-V264 VanDerWaalsContact O-N 3.09Å; V262-V264 PolarHBondContact O-N 3.49Å; V264-L277 HydrophobicContact CG2-CD1 4.1Å
265	L	86.1	Confident	83.2	Confident	78 Å²	78	61.8 Å²	61.8	41%	0.408	33%	0.329	S	S	.	.			trans	-59.1	129.8	-179.9	-76.5	167.5	0	0	0	111	V261 V262 S267 V268 Q269	V261-L265 PolarHBondContact O-N 3.04Å; V262-L265 HydrophobicContact CB-CD1 4.44Å; V262-L265 HydrophobicContact CG2-CD1 4.31Å; V262-L265 WeakPolarHBondContact O-CB 3.39Å; V262-L265 PolarHBondContact O-N 3.15Å; L265-S267 PolarHBondContact O-N 3.2Å; L265-S267 VanDerWaalsContact O-N 3.12Å; L265-V268 HydrophobicContact CB-CG2 4.29Å; L265-V268 WeakPolarHBondContact O-CB 3.27Å; L265-V268 PolarHBondContact O-N 3.18Å; L265-Q269 PolarHBondContact O-N 3.38Å
266	P	82.3	Confident	82.5	Confident	85 Å²	85	60.3 Å²	60.3	55%	0.552	33%	0.327	S	S	*	.	H	α-helix	trans	-58.3	-30.5	-179.9	-26.3	33.7	0	0	0	113.6	V268 R270	P266-V268 VanDerWaalsContact C-N 3.29Å; P266-V268 PolarHBondContact O-N 2.91Å; P266-R270 WeakPolarHBondContact O-CG 3.36Å; P266-R270 PolarHBondContact O-N 3.16Å
267	S	81.8	Confident	82.2	Confident	71 Å²	71	64 Å²	64	50%	0.497	35%	0.346	S	S	.	.	H	α-helix	trans	-63.5	-34	175.6	-57.2	0	0	0	0	112.5	L265 Y271 Q459	L265-S267 PolarHBondContact O-N 3.2Å; L265-S267 VanDerWaalsContact O-N 3.12Å; S267-Y271 WeakPolarHBondContact O-CD2 3.21Å; S267-Q459 PolarHBondContact O-NE2 3.16Å
268	V	80.5	Confident	82.1	Confident	3 Å²	3	59.8 Å²	59.8	2%	0.018	32%	0.324	C	S	.	.	H	α-helix	trans	-73.9	-49.2	177.5	163.9	0	0	0	0	110.4	V262 L265 P266 R270 Y271 Q272 I455 Q459	V262-V268 HydrophobicContact CG1-CG2 4.35Å; V262-V268 WeakPolarHBondContact O-CG2 3.47Å; L265-V268 HydrophobicContact CB-CG2 4.29Å; L265-V268 WeakPolarHBondContact O-CB 3.27Å; L265-V268 PolarHBondContact O-N 3.18Å; P266-V268 VanDerWaalsContact C-N 3.29Å; P266-V268 PolarHBondContact O-N 2.91Å; V268-R270 PolarHBondContact O-N 3.44Å; V268-R270 VanDerWaalsContact O-N 3.1Å; V268-Y271 PolarHBondContact O-N 3.49Å; V268-Q272 PolarHBondContact O-N 3.27Å; V268-I455 HydrophobicContact CB-CG2 4.09Å; V268-I455 HydrophobicContact CG1-CG2 3.3Å; V268-I455 HydrophobicContact CG2-CG2 3.62Å; V268-Q459 VanDerWaalsContact CG2-NE2 3.33Å
269	Q	81.1	Confident	82	Confident	84 Å²	84	57.7 Å²	57.7	39%	0.393	31%	0.306	S	S	.	.	H	α-helix	trans	-62.3	-23.4	-175.6	-67.4	-178.1	-10.8	0	0	113.5	L265 Q272 P273	L265-Q269 PolarHBondContact O-N 3.38Å; Q269-Q272 CarbonylContact O-C 3.13Å; Q269-P273 VanDerWaalsContact O-CA 3.3Å; Q269-P273 WeakPolarHBondContact O-CA 3.21Å
270	R	77.8	Confident	82	Confident	207 Å²	207	57.2 Å²	57.2	78%	0.781	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.5	-35	173.5	-76.8	178.2	-176.2	176.2	2.6	113.6	P266 V268	P266-R270 WeakPolarHBondContact O-CG 3.36Å; P266-R270 PolarHBondContact O-N 3.16Å; V268-R270 PolarHBondContact O-N 3.44Å; V268-R270 VanDerWaalsContact O-N 3.1Å
271	Y	74.1	Confident	82.1	Confident	143 Å²	143	56.5 Å²	56.5	56%	0.561	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.1	-36	179	-66.9	-82.8	0	0	0	111.3	S267 V268 Q459	S267-Y271 WeakPolarHBondContact O-CD2 3.21Å; V268-Y271 PolarHBondContact O-N 3.49Å; Y271-Q459 HydrophobicContact CD2-CB 4.22Å; Y271-Q459 HydrophobicContact CD2-CG 3.85Å; Y271-Q459 HydrophobicContact CE2-CB 4.39Å; Y271-Q459 HydrophobicContact CE2-CG 4.37Å; Y271-Q459 HydrophobicContact CG-CG 4.38Å
272	Q	73	Confident	82.2	Confident	19 Å²	19	55.1 Å²	55.1	9%	0.089	29%	0.285	C	S	.	.			trans	-126.3	79.8	-178.6	-156	172	31.3	0	0	110.8	V268 Q269 K274 S275 E458	V268-Q272 PolarHBondContact O-N 3.27Å; Q269-Q272 CarbonylContact O-C 3.13Å; Q272-K274 PolarHBondContact O-N 3.36Å; Q272-S275 VanDerWaalsContact CG-OG 3.25Å; Q272-S275 WeakPolarHBondContact CG-OG 3.47Å; Q272-S275 WeakPolarHBondContact O-CB 3.38Å; Q272-S275 PolarHBondContact O-N 2.99Å; Q272-S275 PolarHBondContact OE1-OG 3.33Å; Q272-E458 VanDerWaalsContact CB-OE2 3.29Å; Q272-E458 WeakPolarHBondContact CB-OE2 3.33Å; Q272-E458 WeakPolarHBondContact CG-OE2 3.39Å; Q272-E458 PolarHBondContact NE2-OE1 3.24Å; Q272-E458 PolarHBondContact NE2-OE2 3.37Å
273	P	69.2	Low	82.5	Confident	107 Å²	107	53.4 Å²	53.4	70%	0.695	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.7	-19.8	-175.2	26.6	-35.2	0	0	0	113.3	Q269	Q269-P273 VanDerWaalsContact O-CA 3.3Å; Q269-P273 WeakPolarHBondContact O-CA 3.21Å
274	K	69.9	Low	82.8	Confident	61 Å²	61	53.5 Å²	53.5	27%	0.265	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.4	-2.8	176.1	-60.4	-170.9	179.2	179	0	113.2	E196 I199 E200 Q272 Q279	E196-K274 HydrophobicContact CB-CD 4.3Å; E196-K274 HydrophobicContact CG-CB 4.18Å; E196-K274 HydrophobicContact CG-CD 3.82Å; I199-K274 HydrophobicContact CD1-CB 4.34Å; E200-K274 IonicContact OE1-NZ 3.71Å; E200-K274 PolarHBondContact OE1-NZ 3.38Å; Q272-K274 PolarHBondContact O-N 3.36Å; K274-Q279 PolarHBondContact O-NE2 2.81Å; K274-Q279 VanDerWaalsContact O-NE2 3.15Å
275	S	68.1	Low	83.1	Confident	5 Å²	5	50.9 Å²	50.9	4%	0.035	26%	0.261	C	S	.	.			trans	-82.2	132.3	171.6	-82.4	0	0	0	0	111.1	Q272 Q279	Q272-S275 VanDerWaalsContact CG-OG 3.25Å; Q272-S275 WeakPolarHBondContact CG-OG 3.47Å; Q272-S275 WeakPolarHBondContact O-CB 3.38Å; Q272-S275 PolarHBondContact O-N 2.99Å; Q272-S275 PolarHBondContact OE1-OG 3.33Å; S275-Q279 VanDerWaalsContact CA-OE1 3.23Å; S275-Q279 PolarHBondContact OG-OE1 3.1Å
276	G	79.3	Confident	83.4	Confident	22 Å²	22	47.9 Å²	47.9	23%	0.227	24%	0.244	C	C	.	.			trans	-157.1	176.1	-169.3	0	0	0	0	0	114.8	F278 Q279	G276-F278 PolarHBondContact O-N 3.24Å; G276-F278 VanDerWaalsContact O-N 3.14Å; G276-Q279 VanDerWaalsContact N-OE1 3.08Å; G276-Q279 PolarHBondContact O-N 2.98Å
277	L	87.4	Confident	84	Confident	86 Å²	86	44 Å²	44	45%	0.45	22%	0.219	S	C	.	.	H	α-helix	trans	-59.7	-29	-173.7	-169.7	67.2	0	0	0	113.1	Y222 V264 G281	Y222-L277 HydrophobicContact CE2-CD1 3.8Å; Y222-L277 HydrophobicContact CE2-CD2 4.31Å; Y222-L277 HydrophobicContact CE2-CG 3.64Å; Y222-L277 WeakPolarHBondContact CE2-O 3.46Å; Y222-L277 WeakPolarHBondContact OH-CD1 3.38Å; Y222-L277 PolarHBondContact OH-O 3.49Å; V264-L277 HydrophobicContact CG2-CD1 4.1Å; L277-G281 PolarHBondContact O-N 2.8Å
278	F	89.6	Confident	84.6	Confident	10 Å²	10	40.7 Å²	40.7	4%	0.044	20%	0.196	C	C	.	.	H	α-helix	trans	-60.1	-47.3	177.4	170.9	-109.6	0	0	0	112.7	L194 A195 L214 F217 A218 G276 G281 F282	L194-F278 HydrophobicContact CB-CE1 4.28Å; L194-F278 HydrophobicContact CD2-CE1 4.07Å; L194-F278 HydrophobicContact CD2-CZ 3.79Å; L194-F278 HydrophobicContact CG-CE1 4.19Å; L194-F278 HydrophobicContact CG-CZ 4.37Å; A195-F278 HydrophobicContact CB-CD1 3.96Å; L214-F278 HydrophobicContact CD1-CB 3.93Å; L214-F278 HydrophobicContact CD1-CD1 3.91Å; L214-F278 HydrophobicContact CD1-CG 3.83Å; F217-F278 HydrophobicContact CB-CD2 3.96Å; F217-F278 HydrophobicContact CB-CE2 3.6Å; A218-F278 HydrophobicContact CB-CB 4.01Å; A218-F278 HydrophobicContact CB-CD2 4.25Å; G276-F278 PolarHBondContact O-N 3.24Å; G276-F278 VanDerWaalsContact O-N 3.14Å; F278-G281 PolarHBondContact O-N 3.13Å; F278-F282 HydrophobicContact CE2-CB 4.41Å; F278-F282 HydrophobicContact CE2-CD2 4.44Å; F278-F282 HydrophobicContact CZ-CB 4.44Å; F278-F282 HydrophobicContact CZ-CD2 4.3Å; F278-F282 WeakPolarHBondContact O-CB 3.39Å; F278-F282 PolarHBondContact O-N 3.25Å
279	Q	89.8	Confident	85.1	Confident	4 Å²	4	41.5 Å²	41.5	2%	0.019	20%	0.199	C	C	.	.	H	α-helix	trans	-63.7	-47.1	-178.6	-66.2	149	-8.4	0	0	110.3	A191 H192 A195 K274 S275 G276 G281 F282 I283	A191-Q279 HydrophobicContact CB-CG 4.43Å; H192-Q279 VanDerWaalsContact CE1-CD 3.41Å; H192-Q279 PolarHBondContact CE1-OE1 3.34Å; H192-Q279 VanDerWaalsContact CE1-OE1 3.26Å; H192-Q279 PolarHBondContact ND1-NE2 3.29Å; H192-Q279 PolarHBondContact ND1-OE1 2.86Å; A195-Q279 HydrophobicContact CB-CG 4.07Å; A195-Q279 VanDerWaalsContact CB-NE2 3.33Å; K274-Q279 PolarHBondContact O-NE2 2.81Å; K274-Q279 VanDerWaalsContact O-NE2 3.15Å; S275-Q279 VanDerWaalsContact CA-OE1 3.23Å; S275-Q279 PolarHBondContact OG-OE1 3.1Å; G276-Q279 VanDerWaalsContact N-OE1 3.08Å; G276-Q279 PolarHBondContact O-N 2.98Å; Q279-G281 VanDerWaalsContact C-N 3.34Å; Q279-G281 PolarHBondContact O-N 3.2Å; Q279-F282 PolarHBondContact O-N 2.91Å; Q279-I283 WeakPolarHBondContact O-CG1 3.46Å; Q279-I283 PolarHBondContact O-N 2.93Å
280	A	91	Very high	85.6	Confident	1 Å²	1	37.9 Å²	37.9	1%	0.008	18%	0.182	C	C	.	.	H	α-helix	trans	-61.5	-40.1	176.9	0	0	0	0	0	112.6	Y222 A263 S284	Y222-A280 WeakPolarHBondContact OH-CB 3.39Å; A263-A280 HydrophobicContact CB-CB 3.96Å; A280-S284 VanDerWaalsContact O-CB 3.25Å; A280-S284 WeakPolarHBondContact O-CB 3.3Å; A280-S284 PolarHBondContact O-N 2.83Å; A280-S284 PolarHBondContact O-OG 2.96Å
281	G	93	Very high	86.4	Confident	0 Å²	0	28 Å²	28	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-67.7	-44	177.3	0	0	0	0	0	112.9	S221 Y222 L277 F278 Q279 I283 S284 A285	S221-G281 VanDerWaalsContact CB-C 3.49Å; S221-G281 WeakPolarHBondContact OG-CA 3.44Å; Y222-G281 PolarHBondContact OH-N 3.25Å; L277-G281 PolarHBondContact O-N 2.8Å; F278-G281 PolarHBondContact O-N 3.13Å; Q279-G281 VanDerWaalsContact C-N 3.34Å; Q279-G281 PolarHBondContact O-N 3.2Å; G281-I283 PolarHBondContact O-N 3.4Å; G281-S284 PolarHBondContact O-N 3.39Å; G281-A285 PolarHBondContact O-N 3.18Å
282	F	92.8	Very high	87.2	Confident	59 Å²	59	24.4 Å²	24.4	26%	0.259	13%	0.131	S	C	.	.	H	α-helix	trans	-61.5	-44.7	178.1	-173.1	-95.5	0	0	0	111.7	L187 F190 A191 S221 F278 Q279 A285 Y286	L187-F282 HydrophobicContact CD1-CE1 3.69Å; L187-F282 HydrophobicContact CD1-CZ 4.17Å; L187-F282 HydrophobicContact CD2-CE1 4.27Å; L187-F282 HydrophobicContact CG-CE1 3.83Å; F190-F282 HydrophobicContact CD1-CE1 4.11Å; F190-F282 HydrophobicContact CD1-CZ 4.11Å; F190-F282 HydrophobicContact CE1-CE1 4.35Å; F190-F282 AromaticContact CE1-CZ 3.91Å; F190-F282 HydrophobicContact CE1-CZ 3.91Å; A191-F282 HydrophobicContact CB-CD1 3.75Å; A191-F282 HydrophobicContact CB-CE1 4.36Å; A191-F282 HydrophobicContact CB-CG 4.37Å; S221-F282 PolarHBondContact OG-N 3.4Å; F278-F282 HydrophobicContact CE2-CB 4.41Å; F278-F282 HydrophobicContact CE2-CD2 4.44Å; F278-F282 HydrophobicContact CZ-CB 4.44Å; F278-F282 HydrophobicContact CZ-CD2 4.3Å; F278-F282 WeakPolarHBondContact O-CB 3.39Å; F278-F282 PolarHBondContact O-N 3.25Å; Q279-F282 PolarHBondContact O-N 2.91Å; F282-A285 PolarHBondContact O-N 2.89Å; F282-Y286 PolarHBondContact O-N 3.32Å
283	I	91.9	Very high	87.9	Confident	1 Å²	1	23.9 Å²	23.9	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-70.6	-36.2	176.8	-62.9	-57.8	0	0	0	111.8	L187 V188 Q279 G281 A285 Y286 I287 C447 L451	L187-I283 HydrophobicContact CD2-CD1 4.07Å; L187-I283 HydrophobicContact CG-CD1 4.21Å; V188-I283 HydrophobicContact CB-CD1 4.39Å; V188-I283 HydrophobicContact CG2-CD1 3.69Å; V188-I283 HydrophobicContact CG2-CG1 4.12Å; Q279-I283 WeakPolarHBondContact O-CG1 3.46Å; Q279-I283 PolarHBondContact O-N 2.93Å; G281-I283 PolarHBondContact O-N 3.4Å; I283-A285 VanDerWaalsContact C-N 3.33Å; I283-A285 PolarHBondContact O-N 2.79Å; I283-Y286 PolarHBondContact O-N 3.3Å; I283-Y286 VanDerWaalsContact O-N 3.1Å; I283-I287 HydrophobicContact CG2-CD1 4.08Å; I283-I287 HydrophobicContact CG2-CG1 4.4Å; I283-I287 WeakPolarHBondContact O-CG1 3.43Å; I283-I287 PolarHBondContact O-N 3.47Å; I283-C447 VanDerWaalsContact CG2-SG 3.55Å; I283-L451 HydrophobicContact CB-CD2 3.74Å; I283-L451 HydrophobicContact CG1-CD2 4.03Å; I283-L451 HydrophobicContact CG2-CD2 3.75Å
284	S	93.6	Very high	88.8	Confident	4 Å²	4	18.8 Å²	18.8	3%	0.028	10%	0.096	C	C	.	.	H	α-helix	trans	-60.3	-42	173.7	-64.6	0	0	0	0	112.1	A280 G281 Y286 I287 M288	A280-S284 VanDerWaalsContact O-CB 3.25Å; A280-S284 WeakPolarHBondContact O-CB 3.3Å; A280-S284 PolarHBondContact O-N 2.83Å; A280-S284 PolarHBondContact O-OG 2.96Å; G281-S284 PolarHBondContact O-N 3.39Å; S284-Y286 VanDerWaalsContact C-N 3.26Å; S284-Y286 PolarHBondContact O-N 3.32Å; S284-I287 PolarHBondContact O-N 3.25Å; S284-M288 WeakPolarHBondContact O-CG 3.42Å; S284-M288 PolarHBondContact O-N 2.8Å
285	A	93.5	Very high	89.6	Confident	18 Å²	18	15.9 Å²	15.9	15%	0.149	8%	0.083	C	C	.	.	H	α-helix	trans	-60.8	-37.9	174.6	0	0	0	0	0	111.9	A225 G281 F282 I283 M288 F289	A225-A285 HydrophobicContact CB-CB 4.36Å; G281-A285 PolarHBondContact O-N 3.18Å; F282-A285 PolarHBondContact O-N 2.89Å; I283-A285 VanDerWaalsContact C-N 3.33Å; I283-A285 PolarHBondContact O-N 2.79Å; A285-M288 PolarHBondContact O-N 3.14Å; A285-F289 PolarHBondContact O-N 3.4Å
286	Y	92.6	Very high	90.4	Very high	15 Å²	15	16.1 Å²	16.1	6%	0.059	9%	0.085	C	C	.	.	H	α-helix	trans	-72.8	-38.9	177.9	-175.1	-123.8	0	0	0	113.7	Q183 L184 L187 F282 I283 S284 M288 F289 L290 I340	Q183-Y286 PolarHBondContact NE2-OH 2.87Å; L184-Y286 HydrophobicContact CD2-CD1 3.99Å; L184-Y286 HydrophobicContact CD2-CE1 3.29Å; L187-Y286 HydrophobicContact CD2-CD1 3.09Å; L187-Y286 HydrophobicContact CD2-CD2 3.92Å; L187-Y286 HydrophobicContact CD2-CE1 3.45Å; L187-Y286 VanDerWaalsContact CD2-CE1 3.45Å; L187-Y286 HydrophobicContact CD2-CE2 4.32Å; L187-Y286 HydrophobicContact CD2-CG 3.32Å; F282-Y286 PolarHBondContact O-N 3.32Å; I283-Y286 PolarHBondContact O-N 3.3Å; I283-Y286 VanDerWaalsContact O-N 3.1Å; S284-Y286 VanDerWaalsContact C-N 3.26Å; S284-Y286 PolarHBondContact O-N 3.32Å; Y286-M288 PolarHBondContact O-N 2.79Å; Y286-F289 HydrophobicContact CD2-CB 4.42Å; Y286-F289 AromaticContact CD2-CD1 3.8Å; Y286-F289 HydrophobicContact CD2-CD1 3.8Å; Y286-F289 HydrophobicContact CD2-CG 4.48Å; Y286-F289 AromaticContact CE2-CD1 3.59Å; Y286-F289 HydrophobicContact CE2-CD1 3.59Å; Y286-F289 HydrophobicContact CE2-CE1 4.04Å; Y286-F289 WeakPolarHBondContact O-CB 3.28Å; Y286-F289 PolarHBondContact O-N 3.36Å; Y286-F289 VanDerWaalsContact O-N 3.15Å; Y286-L290 HydrophobicContact CD1-CD1 4.36Å; Y286-L290 HydrophobicContact CE1-CD1 4.04Å; Y286-L290 HydrophobicContact CE1-CG 4.37Å; Y286-L290 HydrophobicContact CE2-CD2 4.43Å; Y286-L290 HydrophobicContact CE2-CG 4.35Å; Y286-L290 PolarHBondContact O-N 3.36Å; Y286-I340 HydrophobicContact CD2-CD1 4.27Å; Y286-I340 HydrophobicContact CE2-CD1 3.86Å; Y286-I340 HydrophobicContact CE2-CG2 4.41Å
287	I	93.9	Very high	90.3	Very high	3 Å²	3	15.1 Å²	15.1	2%	0.015	7%	0.074	C	C	.	.	H	α-helix	trans	-57.7	-41.2	170.8	-72.1	170	0	0	0	110	N252 I283 S284 L290 T291 C447 A448	N252-I287 HydrophobicContact CB-CG2 3.92Å; I283-I287 HydrophobicContact CG2-CD1 4.08Å; I283-I287 HydrophobicContact CG2-CG1 4.4Å; I283-I287 WeakPolarHBondContact O-CG1 3.43Å; I283-I287 PolarHBondContact O-N 3.47Å; S284-I287 PolarHBondContact O-N 3.25Å; I287-L290 PolarHBondContact O-N 2.84Å; I287-T291 PolarHBondContact O-N 2.84Å; I287-T291 PolarHBondContact O-OG1 2.82Å; I287-C447 HydrophobicContact CG1-CB 4.29Å; I287-A448 HydrophobicContact CD1-CB 4.02Å
288	M	94.1	Very high	90.1	Very high	2 Å²	2	11.9 Å²	11.9	1%	0.01	6%	0.057	C	C	.	.	H	α-helix	trans	-67.5	-37.6	176.1	-67.6	-55.4	135.5	0	0	112.8	A225 I228 V229 N252 C256 S284 A285 Y286 T291 W292	A225-M288 HydrophobicContact CB-CG 4.21Å; I228-M288 HydrophobicContact CB-CB 3.99Å; I228-M288 HydrophobicContact CD1-CB 4.21Å; I228-M288 HydrophobicContact CG2-CB 3.76Å; V229-M288 HydrophobicContact CG2-CE 4.15Å; V229-M288 HydrophobicContact CG2-CG 3.89Å; V229-M288 HydrophobicContact CG2-SD 3.25Å; V229-M288 WeakPolarHBondContact CG2-SD 3.16Å; N252-M288 VanDerWaalsContact C-CE 3.5Å; N252-M288 HydrophobicContact CB-CE 3.83Å; N252-M288 WeakPolarHBondContact O-CE 3.15Å; C256-M288 HydrophobicContact CB-CE 4.4Å; C256-M288 WeakPolarHBondContact SG-CE 3.42Å; S284-M288 WeakPolarHBondContact O-CG 3.42Å; S284-M288 PolarHBondContact O-N 2.8Å; A285-M288 PolarHBondContact O-N 3.14Å; Y286-M288 PolarHBondContact O-N 2.79Å; M288-T291 WeakPolarHBondContact O-CB 3.42Å; M288-T291 PolarHBondContact O-N 3.04Å; M288-W292 PolarHBondContact O-N 3.19Å
289	F	92.2	Very high	89.3	Confident	20 Å²	20	13 Å²	13	9%	0.088	7%	0.065	C	C	.	.	H	α-helix	trans	-60.6	-45.3	170.1	167	-99.1	0	0	0	112.4	A285 Y286 T291 W292 S293 I336 I340	A285-F289 PolarHBondContact O-N 3.4Å; Y286-F289 HydrophobicContact CD2-CB 4.42Å; Y286-F289 AromaticContact CD2-CD1 3.8Å; Y286-F289 HydrophobicContact CD2-CD1 3.8Å; Y286-F289 HydrophobicContact CD2-CG 4.48Å; Y286-F289 AromaticContact CE2-CD1 3.59Å; Y286-F289 HydrophobicContact CE2-CD1 3.59Å; Y286-F289 HydrophobicContact CE2-CE1 4.04Å; Y286-F289 WeakPolarHBondContact O-CB 3.28Å; Y286-F289 PolarHBondContact O-N 3.36Å; Y286-F289 VanDerWaalsContact O-N 3.15Å; F289-T291 VanDerWaalsContact C-N 3.3Å; F289-T291 PolarHBondContact O-N 3.3Å; F289-W292 AromaticContact CD2-CE3 3.96Å; F289-W292 HydrophobicContact CD2-CE3 3.96Å; F289-W292 HydrophobicContact CD2-CZ3 4.2Å; F289-W292 HydrophobicContact CE2-CE3 4.27Å; F289-W292 HydrophobicContact CE2-CZ3 4.23Å; F289-W292 PolarHBondContact O-N 2.95Å; F289-S293 WeakPolarHBondContact O-CB 3.37Å; F289-S293 PolarHBondContact O-N 2.85Å; F289-I336 HydrophobicContact CD2-CG2 3.98Å; F289-I336 HydrophobicContact CE2-CB 3.72Å; F289-I336 HydrophobicContact CE2-CG2 3.3Å; F289-I336 HydrophobicContact CZ-CB 4.11Å; F289-I336 HydrophobicContact CZ-CG2 3.76Å; F289-I340 HydrophobicContact CD1-CD1 3.91Å; F289-I340 HydrophobicContact CE1-CD1 3.61Å; F289-I340 HydrophobicContact CG-CD1 4.49Å; F289-I340 HydrophobicContact CZ-CD1 3.98Å
290	L	91.7	Very high	88.6	Confident	8 Å²	8	15.7 Å²	15.7	4%	0.042	8%	0.08	C	C	.	.	H	α-helix	trans	-63	-38.3	176.2	-72.1	178.3	0	0	0	111.9	L184 Y286 I287 S293 A294	L184-L290 HydrophobicContact CD2-CD1 3.76Å; Y286-L290 HydrophobicContact CD1-CD1 4.36Å; Y286-L290 HydrophobicContact CE1-CD1 4.04Å; Y286-L290 HydrophobicContact CE1-CG 4.37Å; Y286-L290 HydrophobicContact CE2-CD2 4.43Å; Y286-L290 HydrophobicContact CE2-CG 4.35Å; Y286-L290 PolarHBondContact O-N 3.36Å; I287-L290 PolarHBondContact O-N 2.84Å; L290-S293 PolarHBondContact O-N 3.19Å; L290-A294 WeakPolarHBondContact O-CB 3.38Å; L290-A294 PolarHBondContact O-N 3.15Å
291	T	93.3	Very high	87.7	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-61.4	-49.5	175.4	-51.1	0	0	0	0	110.3	L232 I249 N252 I287 M288 F289 S293 A294 M295 I441	L232-T291 HydrophobicContact CD1-CG2 3.87Å; I249-T291 HydrophobicContact CG1-CG2 4.14Å; N252-T291 PolarHBondContact ND2-OG1 3.08Å; I287-T291 PolarHBondContact O-N 2.84Å; I287-T291 PolarHBondContact O-OG1 2.82Å; M288-T291 WeakPolarHBondContact O-CB 3.42Å; M288-T291 PolarHBondContact O-N 3.04Å; F289-T291 VanDerWaalsContact C-N 3.3Å; F289-T291 PolarHBondContact O-N 3.3Å; T291-S293 PolarHBondContact O-N 3.17Å; T291-A294 WeakPolarHBondContact O-CB 3.48Å; T291-A294 PolarHBondContact O-N 3.17Å; T291-A294 VanDerWaalsContact O-N 3.17Å; T291-M295 WeakPolarHBondContact O-CG 3.44Å; T291-M295 PolarHBondContact O-N 3.41Å; T291-I441 HydrophobicContact CG2-CD1 4.49Å
292	W	91	Very high	87	Confident	68 Å²	68	23.8 Å²	23.8	26%	0.258	13%	0.131	S	C	.	.	H	α-helix	trans	-58.9	-47.8	175.4	173.3	39.1	0	0	0	112.3	I228 L232 F236 M288 F289 A294 M295 S296 I336	I228-W292 HydrophobicContact CG2-CB 4.36Å; L232-W292 HydrophobicContact CD1-CB 4.44Å; L232-W292 HydrophobicContact CD2-CB 3.81Å; L232-W292 HydrophobicContact CD2-CG 4.2Å; F236-W292 AromaticContact CE2-CD1 3.83Å; M288-W292 PolarHBondContact O-N 3.19Å; F289-W292 AromaticContact CD2-CE3 3.96Å; F289-W292 HydrophobicContact CD2-CE3 3.96Å; F289-W292 HydrophobicContact CD2-CZ3 4.2Å; F289-W292 HydrophobicContact CE2-CE3 4.27Å; F289-W292 HydrophobicContact CE2-CZ3 4.23Å; F289-W292 PolarHBondContact O-N 2.95Å; W292-A294 PolarHBondContact O-N 2.86Å; W292-M295 PolarHBondContact O-N 3.44Å; W292-M295 VanDerWaalsContact O-N 3.12Å; W292-S296 PolarHBondContact NE1-OG 2.93Å; W292-S296 PolarHBondContact O-N 3.48Å; W292-S296 PolarHBondContact O-OG 2.79Å; W292-I336 HydrophobicContact CH2-CD1 3.6Å; W292-I336 HydrophobicContact CZ3-CD1 3.48Å; W292-I336 VanDerWaalsContact CZ3-CD1 3.48Å
293	S	88.4	Confident	86.4	Confident	8 Å²	8	21.3 Å²	21.3	6%	0.056	12%	0.121	C	C	.	.	H	α-helix	trans	-61	-29.4	178.3	-165	0	0	0	0	112.7	F289 L290 T291 K440	F289-S293 WeakPolarHBondContact O-CB 3.37Å; F289-S293 PolarHBondContact O-N 2.85Å; L290-S293 PolarHBondContact O-N 3.19Å; T291-S293 PolarHBondContact O-N 3.17Å; S293-K440 WeakPolarHBondContact O-CD 3.14Å; S293-K440 PolarHBondContact O-NZ 3.22Å; S293-K440 WeakPolarHBondContact OG-CE 3.21Å; S293-K440 PolarHBondContact OG-NZ 3Å
294	A	88.3	Confident	85.8	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-72.9	-46.5	173.4	0	0	0	0	0	111.4	L290 T291 W292 S296 N297 V437 K440 I441	L290-A294 WeakPolarHBondContact O-CB 3.38Å; L290-A294 PolarHBondContact O-N 3.15Å; T291-A294 WeakPolarHBondContact O-CB 3.48Å; T291-A294 PolarHBondContact O-N 3.17Å; T291-A294 VanDerWaalsContact O-N 3.17Å; W292-A294 PolarHBondContact O-N 2.86Å; A294-S296 VanDerWaalsContact C-N 3.32Å; A294-S296 PolarHBondContact O-N 3.31Å; A294-N297 PolarHBondContact O-N 3.11Å; A294-V437 HydrophobicContact CB-CG1 4.12Å; A294-V437 WeakPolarHBondContact O-CG2 3.48Å; A294-K440 HydrophobicContact CB-CB 3.76Å; A294-K440 HydrophobicContact CB-CD 4.31Å; A294-I441 HydrophobicContact CB-CD1 3.76Å; A294-I441 HydrophobicContact CB-CG1 3.82Å
295	M	86.7	Confident	84.7	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-67.8	-31.7	-178.1	-55.4	-57.1	79.9	0	0	112.6	F236 N245 F248 T291 W292 N297 E298 V437 I441	F236-M295 HydrophobicContact CB-CB 4.22Å; F236-M295 HydrophobicContact CB-CG 4.47Å; F236-M295 HydrophobicContact CD1-CB 3.51Å; F236-M295 HydrophobicContact CD2-CB 4.43Å; F236-M295 HydrophobicContact CE1-CB 3.9Å; F236-M295 HydrophobicContact CG-CB 3.8Å; F236-M295 HydrophobicContact CG-CG 4.49Å; F236-M295 HydrophobicContact CZ-CB 4.49Å; N245-M295 HydrophobicContact CB-SD 3.68Å; N245-M295 PolarHBondContact OD1-SD 3.48Å; F248-M295 HydrophobicContact CD2-CE 3.73Å; F248-M295 HydrophobicContact CD2-SD 4.31Å; F248-M295 HydrophobicContact CE2-CE 4.42Å; T291-M295 WeakPolarHBondContact O-CG 3.44Å; T291-M295 PolarHBondContact O-N 3.41Å; W292-M295 PolarHBondContact O-N 3.44Å; W292-M295 VanDerWaalsContact O-N 3.12Å; M295-N297 PolarHBondContact O-N 3.23Å; M295-E298 WeakPolarHBondContact O-CB 3.22Å; M295-E298 PolarHBondContact O-N 2.98Å; M295-E298 VanDerWaalsContact O-N 3.15Å; M295-V437 HydrophobicContact CE-CG1 3.75Å; M295-I441 HydrophobicContact CE-CD1 4.22Å; M295-I441 HydrophobicContact CE-CG1 4.48Å
296	S	83.3	Confident	83.3	Confident	10 Å²	10	26.3 Å²	26.3	7%	0.07	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.3	-17.5	172.2	-61.1	0	0	0	0	113.8	W292 A294 N304 N431	W292-S296 PolarHBondContact NE1-OG 2.93Å; W292-S296 PolarHBondContact O-N 3.48Å; W292-S296 PolarHBondContact O-OG 2.79Å; A294-S296 VanDerWaalsContact C-N 3.32Å; A294-S296 PolarHBondContact O-N 3.31Å; S296-N304 PolarHBondContact O-ND2 2.85Å; S296-N431 PolarHBondContact O-ND2 3.12Å
297	N	79	Confident	81.5	Confident	1 Å²	1	31.2 Å²	31.2	1%	0.005	18%	0.178	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.5	7.4	179.1	-71	6.2	0	0	0	113	A294 M295 E333 S432 N433 S436 V437 K440	A294-N297 PolarHBondContact O-N 3.11Å; M295-N297 PolarHBondContact O-N 3.23Å; N297-E333 PolarHBondContact OD1-OE1 3.42Å; N297-S432 CarbonylContact O-C 3.53Å; N297-S432 VanDerWaalsContact O-CA 3.22Å; N297-S432 WeakPolarHBondContact O-CA 3.19Å; N297-S432 WeakPolarHBondContact O-CB 3.31Å; N297-N433 PolarHBondContact O-N 3.5Å; N297-S436 PolarHBondContact ND2-OG 3.26Å; N297-V437 HydrophobicContact CB-CG2 4.15Å; N297-V437 WeakPolarHBondContact O-CG2 3.25Å; N297-K440 PolarHBondContact ND2-NZ 3.04Å
298	E	81.4	Confident	79.4	Confident	18 Å²	18	36.9 Å²	36.9	8%	0.084	21%	0.207	C	C	.	.			trans	-69.7	131.4	176	-176.2	61.9	-144.1	0	0	110.3	M295 D300 C303 N304 S432	M295-E298 WeakPolarHBondContact O-CB 3.22Å; M295-E298 PolarHBondContact O-N 2.98Å; M295-E298 VanDerWaalsContact O-N 3.15Å; E298-D300 VanDerWaalsContact C-N 3.33Å; E298-D300 HydrophobicContact CG-CB 4.39Å; E298-D300 PolarHBondContact O-N 3.2Å; E298-C303 HydrophobicContact CG-CB 4.43Å; E298-N304 HydrophobicContact CB-CB 4.4Å; E298-N304 PolarHBondContact O-ND2 3.12Å; E298-S432 VanDerWaalsContact O-CB 3.32Å; E298-S432 WeakPolarHBondContact O-CB 3.43Å
299	P	74	Confident	77.4	Confident	32 Å²	32	39.4 Å²	39.4	21%	0.208	23%	0.225	C	C	.	.	S	Bend	trans	-72.6	-17.7	-178.6	27.6	-36.3	0	0	0	116	P301 S432 M434	P299-P301 VanDerWaalsContact O-CD 3.26Å; P299-P301 WeakPolarHBondContact O-CD 3.41Å; P299-S432 WeakPolarHBondContact CA-OG 3.39Å; P299-M434 WeakPolarHBondContact CD-SD 3.34Å; P299-M434 HydrophobicContact CG-CG 3.91Å; P299-M434 HydrophobicContact CG-SD 3.6Å; P299-M434 VanDerWaalsContact CG-SD 3.6Å
300	D	75.8	Confident	75.7	Confident	62 Å²	62	41.7 Å²	41.7	33%	0.332	24%	0.237	S	C	.	.			trans	-77.9	112.8	177.7	-167	-16	0	0	0	111	E298 V302 C303 N304	E298-D300 VanDerWaalsContact C-N 3.33Å; E298-D300 HydrophobicContact CG-CB 4.39Å; E298-D300 PolarHBondContact O-N 3.2Å; D300-V302 PolarHBondContact O-N 3.4Å; D300-V302 WeakPolarHBondContact OD1-CB 3.46Å; D300-V302 WeakPolarHBondContact OD1-CG2 3.45Å; D300-V302 PolarHBondContact OD1-N 3.25Å; D300-C303 HydrophobicContact CB-CB 4.16Å; D300-C303 PolarHBondContact O-N 2.99Å; D300-C303 VanDerWaalsContact O-N 3.11Å; D300-N304 WeakPolarHBondContact O-CB 3.4Å; D300-N304 PolarHBondContact O-N 2.91Å
301	P	70.9	Confident	73.7	Confident	94 Å²	94	48.5 Å²	48.5	61%	0.61	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.6	-19.6	179.2	29.3	-36.7	0	0	0	113.2	P299 N304	P299-P301 VanDerWaalsContact O-CD 3.26Å; P299-P301 WeakPolarHBondContact O-CD 3.41Å; P301-N304 CarbonylContact O-C 3.6Å
302	V	78.4	Confident	71.5	Confident	77 Å²	77	55.5 Å²	55.5	47%	0.467	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.4	-40.3	174.1	-179.3	0	0	0	0	110.1	D239 D300	D239-V302 HydrophobicContact CB-CG1 4.08Å; D300-V302 PolarHBondContact O-N 3.4Å; D300-V302 WeakPolarHBondContact OD1-CB 3.46Å; D300-V302 WeakPolarHBondContact OD1-CG2 3.45Å; D300-V302 PolarHBondContact OD1-N 3.25Å
303	C	81.1	Confident	69.6	Low	7 Å²	7	56.7 Å²	56.7	5%	0.047	31%	0.314	C	S	.	.	T	Hydrogen-bonded Turn	trans	-90.9	-11.9	-177.3	-57.9	0	0	0	0	113.8	F236 C242 N245 E298 D300	F236-C303 VanDerWaalsContact CD1-O 3.28Å; F236-C303 WeakPolarHBondContact CD1-O 3.46Å; C242-C303 WeakPolarHBondContact CA-SG 3.22Å; C242-C303 HydrophobicContact CB-CB 3.84Å; C242-C303 WeakPolarHBondContact CB-SG 3.43Å; C242-C303 WeakPolarHBondContact SG-CA 3.36Å; C242-C303 WeakPolarHBondContact SG-CB 3.2Å; C242-C303 CovalentContact SG-SG 2.03Å; C242-C303 PolarHBondContact SG-SG 3.41Å; N245-C303 PolarHBondContact ND2-O 2.89Å; E298-C303 HydrophobicContact CG-CB 4.43Å; D300-C303 HydrophobicContact CB-CB 4.16Å; D300-C303 PolarHBondContact O-N 2.99Å; D300-C303 VanDerWaalsContact O-N 3.11Å
304	N	78.1	Confident	67.8	Low	33 Å²	33	62.1 Å²	62.1	18%	0.176	35%	0.352	C	S	.	.	S	Bend	trans	-127.1	74.9	177	-175.7	9	0	0	0	110.1	S296 E298 D300 P301 S306	S296-N304 PolarHBondContact O-ND2 2.85Å; E298-N304 HydrophobicContact CB-CB 4.4Å; E298-N304 PolarHBondContact O-ND2 3.12Å; D300-N304 WeakPolarHBondContact O-CB 3.4Å; D300-N304 PolarHBondContact O-N 2.91Å; P301-N304 CarbonylContact O-C 3.6Å; N304-S306 PolarHBondContact O-N 3.23Å
305	P	70.7	Confident	65.6	Low	32 Å²	32	70 Å²	70	21%	0.208	39%	0.394	C	S	.	.			trans	-68.8	119.8	178	27.7	-33.1	0	0	0	109.9	Y235 I310	Y235-P305 WeakPolarHBondContact O-CG 3.33Å; P305-I310 HydrophobicContact CB-CD1 4.41Å; P305-I310 HydrophobicContact CB-CG1 4.2Å; P305-I310 HydrophobicContact CG-CD1 4.33Å
306	S	64.2	Low	63.2	Low	63 Å²	63	74.4 Å²	74.4	44%	0.441	43%	0.425	S	S	.	.			trans	-58.6	150.9	169.3	70.1	0	0	0	0	110.6	N304 I308 S309 I310	N304-S306 PolarHBondContact O-N 3.23Å; S306-I308 PolarHBondContact O-N 3.44Å; S306-S309 PolarHBondContact N-OG 2.96Å; S306-S309 PolarHBondContact O-N 3.25Å; S306-S309 PolarHBondContact O-OG 3.36Å; S306-S309 PolarHBondContact OG-OG 2.94Å; S306-I310 PolarHBondContact O-N 3.39Å
307	L	55.7	Low	60.8	Low	117 Å²	117	81.2 Å²	81.2	61%	0.613	47%	0.466	S	S	*	.	H	α-helix	trans	-48.9	-31.8	174.6	-84.8	161.4	0	0	0	112.5	I310 F311	L307-I310 PolarHBondContact O-N 3.03Å; L307-F311 HydrophobicContact CD2-CD2 4.46Å; L307-F311 HydrophobicContact CD2-CE2 3.91Å; L307-F311 VanDerWaalsContact O-CD2 3.28Å; L307-F311 WeakPolarHBondContact O-CD2 3.26Å; L307-F311 PolarHBondContact O-N 2.91Å; L307-F311 VanDerWaalsContact O-N 3.1Å
308	I	49.1	Very low	58.6	Low	123 Å²	123	86.8 Å²	86.8	63%	0.631	50%	0.5	S	S	*	.	H	α-helix	trans	-65.8	-42.3	179.8	-61.3	172.7	0	0	0	111.5	S306 I310 F311 F312	S306-I308 PolarHBondContact O-N 3.44Å; I308-I310 PolarHBondContact O-N 2.9Å; I308-F311 PolarHBondContact O-N 2.57Å; I308-F312 HydrophobicContact CG2-CD2 4.16Å; I308-F312 WeakPolarHBondContact O-CB 3.41Å; I308-F312 PolarHBondContact O-N 3.33Å
309	S	53.5	Low	56.1	Low	55 Å²	55	91.8 Å²	91.8	39%	0.385	53%	0.532	S	S	.	.	H	α-helix	trans	-71	-19.8	177.4	47.8	0	0	0	0	113.2	S306	S306-S309 PolarHBondContact N-OG 2.96Å; S306-S309 PolarHBondContact O-N 3.25Å; S306-S309 PolarHBondContact O-OG 3.36Å; S306-S309 PolarHBondContact OG-OG 2.94Å
310	I	56	Low	54.1	Low	67 Å²	67	96 Å²	96	34%	0.344	56%	0.559	S	S	.	*	H	α-helix	trans	-80.6	-40.4	176.1	-62.2	168.3	0	0	0	111	Y235 P305 S306 L307 I308	Y235-I310 HydrophobicContact CD1-CD1 3.6Å; Y235-I310 HydrophobicContact CD1-CG1 4.33Å; Y235-I310 HydrophobicContact CE1-CD1 3.83Å; Y235-I310 HydrophobicContact CE1-CG1 4.41Å; Y235-I310 HydrophobicContact CE1-CG2 3.96Å; Y235-I310 HydrophobicContact CG-CD1 4.5Å; P305-I310 HydrophobicContact CB-CD1 4.41Å; P305-I310 HydrophobicContact CB-CG1 4.2Å; P305-I310 HydrophobicContact CG-CD1 4.33Å; S306-I310 PolarHBondContact O-N 3.39Å; L307-I310 PolarHBondContact O-N 3.03Å; I308-I310 PolarHBondContact O-N 2.9Å
311	F	48.9	Very low	51.7	Low	151 Å²	151	96.4 Å²	96.4	66%	0.662	57%	0.571	S	S	*	*	H	α-helix	trans	-85.1	-23.1	178.9	-75.7	-72.9	0	0	0	113.9	L307 I308	L307-F311 HydrophobicContact CD2-CD2 4.46Å; L307-F311 HydrophobicContact CD2-CE2 3.91Å; L307-F311 VanDerWaalsContact O-CD2 3.28Å; L307-F311 WeakPolarHBondContact O-CD2 3.26Å; L307-F311 PolarHBondContact O-N 2.91Å; L307-F311 VanDerWaalsContact O-N 3.1Å; I308-F311 PolarHBondContact O-N 2.57Å
312	F	46.7	Very low	49.6	Very low	148 Å²	148	98.3 Å²	98.3	65%	0.649	58%	0.583	S	S	*	*	S	Bend	trans	-127.2	84.3	179.9	-58	-79.7	0	0	0	110.3	I308 S314	I308-F312 HydrophobicContact CG2-CD2 4.16Å; I308-F312 WeakPolarHBondContact O-CB 3.41Å; I308-F312 PolarHBondContact O-N 3.33Å; F312-S314 PolarHBondContact O-N 3.1Å
313	P	51.4	Low	47.4	Very low	93 Å²	93	98.6 Å²	98.6	60%	0.604	59%	0.589	S	S	*	*			trans	-61.7	138.9	173.7	24.7	-31.3	0	0	0	109.6	N315	P313-N315 PolarHBondContact O-N 3.02Å
314	S	50.1	Low	45	Very low	122 Å²	122	102.8 Å²	102.8	85%	0.853	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.5	20.3	-167.8	-43.2	0	0	0	0	116.8	F312	F312-S314 PolarHBondContact O-N 3.1Å
315	N	43.5	Very low	43.3	Very low	166 Å²	166	104 Å²	104	89%	0.888	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.5	10.7	178.3	-129.5	32.2	0	0	0	114	P313	P313-N315 PolarHBondContact O-N 3.02Å
316	S	36.4	Very low	42.4	Very low	92 Å²	92	106.9 Å²	106.9	64%	0.643	64%	0.643	S	S	*	*	S	Bend	trans	-109.2	117.8	171.3	-63.3	0	0	0	0	108.9	V318	S316-V318 PolarHBondContact O-N 3.41Å
317	T	32.5	Very low	41.9	Very low	152 Å²	152	107.2 Å²	107.2	93%	0.933	64%	0.635	S	S	*	*			trans	-66.7	63.5	172.1	42.9	0	0	0	0	111.8
318	V	33.5	Very low	42.3	Very low	118 Å²	118	101.8 Å²	101.8	72%	0.715	61%	0.608	S	S	*	*			trans	-106.1	93.7	163.6	-175.2	0	0	0	0	105.4	S316	S316-V318 PolarHBondContact O-N 3.41Å
319	T	28.7	Very low	43.1	Very low	123 Å²	123	97.9 Å²	97.9	76%	0.755	60%	0.597	S	S	*	*			trans	-48.9	128.6	159.1	33.1	0	0	0	0	107.3	A321	T319-A321 PolarHBondContact O-N 3.01Å
320	P	30.7	Very low	44	Very low	120 Å²	120	97.4 Å²	97.4	78%	0.779	59%	0.592	S	S	*	*			trans	-62.2	112.8	172.3	25.6	-28.9	0	0	0	105.8
321	A	25.2	Very low	44.8	Very low	72 Å²	72	95 Å²	95	60%	0.595	58%	0.581	S	S	*	*			trans	-50.7	140.7	157.1	0	0	0	0	0	106.2	T319 S323	T319-A321 PolarHBondContact O-N 3.01Å; A321-S323 PolarHBondContact O-N 3.44Å
322	P	28.3	Very low	46.1	Very low	133 Å²	133	91 Å²	91	86%	0.864	57%	0.572	S	S	*	*			trans	-67.4	78.3	169.9	29.6	-31.5	0	0	0	106.7	S324	P322-S324 PolarHBondContact O-N 2.92Å
323	S	30.5	Very low	47.7	Very low	84 Å²	84	84.3 Å²	84.3	59%	0.587	54%	0.542	S	S	*	.			trans	-66.7	94.5	169	53.7	0	0	0	0	105.7	A321	A321-S323 PolarHBondContact O-N 3.44Å
324	S	32.6	Very low	49.3	Very low	95 Å²	95	80.1 Å²	80.1	66%	0.664	52%	0.516	S	S	*	.	S	Bend	trans	43	96.7	132.4	58	0	0	0	0	114.8	P322	P322-S324 PolarHBondContact O-N 2.92Å
325	S	40.9	Very low	50.9	Low	59 Å²	59	79.9 Å²	79.9	41%	0.413	50%	0.502	S	S	.	.			trans	45.5	79.1	154.6	59.8	0	0	0	0	115.6	Y327	S325-Y327 VanDerWaalsContact O-CD2 3.23Å; S325-Y327 WeakPolarHBondContact O-CD2 3.32Å; S325-Y327 PolarHBondContact O-N 3.39Å; S325-Y327 VanDerWaalsContact OG-CE2 3.23Å; S325-Y327 WeakPolarHBondContact OG-CE2 3.35Å
326	N	52.2	Low	53.1	Low	92 Å²	92	75.3 Å²	75.3	49%	0.492	48%	0.477	S	S	.	.			trans	-63.1	87.9	163.1	-70.6	-29.9	0	0	0	109.3
327	Y	54.5	Low	55.6	Low	69 Å²	69	71 Å²	71	27%	0.271	45%	0.448	S	S	.	.			trans	-68.6	148.9	168.9	-72.4	-74.4	0	0	0	109.5	P60 Q63 S325 G329	P60-Y327 HydrophobicContact CB-CD2 4.05Å; P60-Y327 HydrophobicContact CB-CG 4.35Å; Q63-Y327 HydrophobicContact CB-CD1 3.98Å; Q63-Y327 HydrophobicContact CB-CE1 4.24Å; Q63-Y327 VanDerWaalsContact OE1-CD1 3.28Å; S325-Y327 VanDerWaalsContact O-CD2 3.23Å; S325-Y327 WeakPolarHBondContact O-CD2 3.32Å; S325-Y327 PolarHBondContact O-N 3.39Å; S325-Y327 VanDerWaalsContact OG-CE2 3.23Å; S325-Y327 WeakPolarHBondContact OG-CE2 3.35Å; Y327-G329 PolarHBondContact O-N 3.25Å
328	A	62.4	Low	58.3	Low	4 Å²	4	64.8 Å²	64.8	3%	0.033	41%	0.408	C	S	.	.			trans	-58.3	124.7	175.2	0	0	0	0	0	110.7	Q63 Y87	Q63-A328 PolarHBondContact NE2-O 2.91Å; Y87-A328 HydrophobicContact CD1-CB 3.71Å; Y87-A328 HydrophobicContact CD2-CB 3.97Å; Y87-A328 HydrophobicContact CE1-CB 3.62Å; Y87-A328 HydrophobicContact CE2-CB 3.9Å; Y87-A328 HydrophobicContact CG-CB 3.87Å
329	G	66.7	Low	61.1	Low	40 Å²	40	62.8 Å²	62.8	41%	0.412	40%	0.396	S	S	.	.			trans	-127.2	160.6	-179	0	0	0	0	0	111.9	Y87 Y327 N418	Y87-G329 PolarHBondContact OH-O 3.44Å; Y87-G329 VanDerWaalsContact OH-O 3.13Å; Y327-G329 PolarHBondContact O-N 3.25Å; G329-N418 PolarHBondContact O-ND2 3.48Å
330	V	72	Confident	64.1	Low	46 Å²	46	58.4 Å²	58.4	28%	0.279	37%	0.368	S	S	.	.			trans	-87.7	132.1	177.5	-172.9	0	0	0	0	109.3	L58 M335 L416	L58-V330 HydrophobicContact CD1-CG2 3.6Å; L58-V330 HydrophobicContact CD2-CG2 4.48Å; L58-V330 HydrophobicContact CG-CG2 4.45Å; V330-M335 HydrophobicContact CB-CG 4.34Å; V330-M335 HydrophobicContact CG1-CG 3.78Å; V330-L416 HydrophobicContact CG2-CD2 4.23Å
331	S	73.1	Confident	67	Low	16 Å²	16	53 Å²	53	11%	0.112	33%	0.332	C	S	.	.			trans	-75.6	157.3	176.6	64.7	0	0	0	0	111.9	E333 S334 M335 N418	S331-E333 VanDerWaalsContact C-N 3.31Å; S331-E333 WeakPolarHBondContact CB-OE1 3.37Å; S331-E333 WeakPolarHBondContact CB-OE2 3.28Å; S331-E333 PolarHBondContact O-N 3.4Å; S331-E333 PolarHBondContact OG-OE1 2.9Å; S331-E333 PolarHBondContact OG-OE2 3.47Å; S331-S334 PolarHBondContact O-N 2.78Å; S331-S334 WeakPolarHBondContact OG-CB 3.44Å; S331-S334 PolarHBondContact OG-OG 2.84Å; S331-M335 WeakPolarHBondContact O-CG 3.5Å; S331-M335 PolarHBondContact O-N 3.14Å; S331-M335 VanDerWaalsContact O-N 3.08Å; S331-N418 PolarHBondContact N-OD1 3.3Å; S331-N418 VanDerWaalsContact N-OD1 3.15Å; S331-N418 PolarHBondContact OG-OD1 2.85Å
332	S	75.6	Confident	70.2	Confident	66 Å²	66	52.4 Å²	52.4	46%	0.462	32%	0.318	S	S	.	.	H	α-helix	trans	-66.2	-33.1	-173.8	55.1	0	0	0	0	112.6	M335 I336	S332-M335 PolarHBondContact O-N 3.33Å; S332-I336 WeakPolarHBondContact O-CG1 3.3Å; S332-I336 PolarHBondContact O-N 3.31Å; S332-I336 VanDerWaalsContact O-N 3.16Å
333	E	81.8	Confident	73.2	Confident	8 Å²	8	52.5 Å²	52.5	4%	0.037	31%	0.306	C	S	.	.	H	α-helix	trans	-65.6	-39.6	174.8	71.4	-75.6	178.5	0	0	112.1	N297 S331 I336 G337 N431	N297-E333 PolarHBondContact OD1-OE1 3.42Å; S331-E333 VanDerWaalsContact C-N 3.31Å; S331-E333 WeakPolarHBondContact CB-OE1 3.37Å; S331-E333 WeakPolarHBondContact CB-OE2 3.28Å; S331-E333 PolarHBondContact O-N 3.4Å; S331-E333 PolarHBondContact OG-OE1 2.9Å; S331-E333 PolarHBondContact OG-OE2 3.47Å; E333-I336 PolarHBondContact O-N 3.1Å; E333-G337 PolarHBondContact O-N 2.82Å; E333-N431 PolarHBondContact OE1-ND2 3.45Å
334	S	83.6	Confident	76	Confident	6 Å²	6	48.8 Å²	48.8	4%	0.042	28%	0.279	C	S	.	.	H	α-helix	trans	-67.4	-37.8	176.7	-66.5	0	0	0	0	111.2	S331 G337 M338 S415 N418	S331-S334 PolarHBondContact O-N 2.78Å; S331-S334 WeakPolarHBondContact OG-CB 3.44Å; S331-S334 PolarHBondContact OG-OG 2.84Å; S334-G337 PolarHBondContact O-N 3.37Å; S334-M338 WeakPolarHBondContact O-CG 3.45Å; S334-M338 PolarHBondContact O-N 3.08Å; S334-S415 WeakPolarHBondContact CB-O 3.29Å; S334-S415 PolarHBondContact OG-O 2.84Å; S334-N418 PolarHBondContact OG-OD1 2.84Å
335	M	84.9	Confident	78.6	Confident	116 Å²	116	44.5 Å²	44.5	57%	0.571	25%	0.249	S	C	*	.	H	α-helix	trans	-61.4	-45.2	174.5	-69.1	-169.1	71.9	0	0	112.4	V330 S331 S332 G337 M338 V339	V330-M335 HydrophobicContact CB-CG 4.34Å; V330-M335 HydrophobicContact CG1-CG 3.78Å; S331-M335 WeakPolarHBondContact O-CG 3.5Å; S331-M335 PolarHBondContact O-N 3.14Å; S331-M335 VanDerWaalsContact O-N 3.08Å; S332-M335 PolarHBondContact O-N 3.33Å; M335-G337 VanDerWaalsContact C-N 3.32Å; M335-G337 PolarHBondContact O-N 2.86Å; M335-M338 PolarHBondContact O-N 3.29Å; M335-V339 WeakPolarHBondContact O-CG2 3.23Å; M335-V339 PolarHBondContact O-N 3.16Å; M335-V339 VanDerWaalsContact O-N 3.09Å
336	I	88.9	Confident	80.7	Confident	70 Å²	70	44.4 Å²	44.4	36%	0.359	24%	0.243	S	C	.	.	H	α-helix	trans	-64.9	-40.9	176.9	-63.3	166	0	0	0	110.1	F289 W292 S332 E333 M338 V339 I340	F289-I336 HydrophobicContact CD2-CG2 3.98Å; F289-I336 HydrophobicContact CE2-CB 3.72Å; F289-I336 HydrophobicContact CE2-CG2 3.3Å; F289-I336 HydrophobicContact CZ-CB 4.11Å; F289-I336 HydrophobicContact CZ-CG2 3.76Å; W292-I336 HydrophobicContact CH2-CD1 3.6Å; W292-I336 HydrophobicContact CZ3-CD1 3.48Å; W292-I336 VanDerWaalsContact CZ3-CD1 3.48Å; S332-I336 WeakPolarHBondContact O-CG1 3.3Å; S332-I336 PolarHBondContact O-N 3.31Å; S332-I336 VanDerWaalsContact O-N 3.16Å; E333-I336 PolarHBondContact O-N 3.1Å; I336-M338 VanDerWaalsContact C-N 3.28Å; I336-M338 PolarHBondContact O-N 3.31Å; I336-V339 PolarHBondContact O-N 3.37Å; I336-V339 VanDerWaalsContact O-N 3.16Å; I336-I340 HydrophobicContact CG2-CD1 4.2Å; I336-I340 WeakPolarHBondContact O-CG1 3.29Å; I336-I340 PolarHBondContact O-N 3.37Å
337	G	88.6	Confident	82.2	Confident	3 Å²	3	41.4 Å²	41.4	3%	0.031	23%	0.225	C	C	.	.	H	α-helix	trans	-57.6	-38.1	173.9	0	0	0	0	0	113.4	E333 S334 M335 I340 W341 Y411	E333-G337 PolarHBondContact O-N 2.82Å; S334-G337 PolarHBondContact O-N 3.37Å; M335-G337 VanDerWaalsContact C-N 3.32Å; M335-G337 PolarHBondContact O-N 2.86Å; G337-I340 PolarHBondContact O-N 3.33Å; G337-W341 WeakPolarHBondContact O-CB 3.38Å; G337-W341 PolarHBondContact O-N 3.48Å; G337-Y411 PolarHBondContact O-OH 3.16Å
338	M	90	Very high	83.4	Confident	21 Å²	21	38.4 Å²	38.4	10%	0.103	21%	0.214	C	C	.	.	H	α-helix	trans	-70.4	-34.7	176.3	-73.7	-58.7	-57.8	0	0	113.1	T51 S334 M335 I336 W341 L342 Y411 V412 L416	T51-M338 HydrophobicContact CG2-CE 3.36Å; S334-M338 WeakPolarHBondContact O-CG 3.45Å; S334-M338 PolarHBondContact O-N 3.08Å; M335-M338 PolarHBondContact O-N 3.29Å; I336-M338 VanDerWaalsContact C-N 3.28Å; I336-M338 PolarHBondContact O-N 3.31Å; M338-W341 HydrophobicContact CE-CD2 4.26Å; M338-W341 HydrophobicContact CE-CE3 3.85Å; M338-W341 HydrophobicContact CE-CZ3 4.17Å; M338-W341 WeakPolarHBondContact O-CB 3.24Å; M338-W341 PolarHBondContact O-N 3.33Å; M338-L342 PolarHBondContact O-N 3.15Å; M338-Y411 HydrophobicContact SD-CE1 4.43Å; M338-V412 HydrophobicContact CE-CB 4.23Å; M338-V412 HydrophobicContact CE-CG1 3.9Å; M338-V412 HydrophobicContact CE-CG2 3.7Å; M338-V412 HydrophobicContact SD-CB 4.43Å; M338-V412 HydrophobicContact SD-CG1 4.42Å; M338-V412 HydrophobicContact SD-CG2 4.18Å; M338-L416 HydrophobicContact CG-CD2 4.25Å
339	V	91.8	Very high	84	Confident	76 Å²	76	38.4 Å²	38.4	46%	0.461	21%	0.214	S	C	.	.	H	α-helix	trans	-65.6	-44.1	173.5	172.1	0	0	0	0	110.5	M335 I336 L342 F343	M335-V339 WeakPolarHBondContact O-CG2 3.23Å; M335-V339 PolarHBondContact O-N 3.16Å; M335-V339 VanDerWaalsContact O-N 3.09Å; I336-V339 PolarHBondContact O-N 3.37Å; I336-V339 VanDerWaalsContact O-N 3.16Å; V339-L342 WeakPolarHBondContact O-CB 3.33Å; V339-L342 PolarHBondContact O-N 3.41Å; V339-F343 HydrophobicContact CG1-CD2 3.85Å; V339-F343 HydrophobicContact CG1-CE2 3.46Å; V339-F343 VanDerWaalsContact CG1-CE2 3.46Å; V339-F343 WeakPolarHBondContact O-CD2 3.33Å; V339-F343 PolarHBondContact O-N 2.93Å; V339-F343 VanDerWaalsContact O-N 3.14Å
340	I	90.9	Very high	84.2	Confident	31 Å²	31	41.3 Å²	41.3	16%	0.159	22%	0.219	C	C	.	.	H	α-helix	trans	-61.5	-46	175.9	-63.6	171	0	0	0	110.4	Y286 F289 I336 G337 L342 F343 I344	Y286-I340 HydrophobicContact CD2-CD1 4.27Å; Y286-I340 HydrophobicContact CE2-CD1 3.86Å; Y286-I340 HydrophobicContact CE2-CG2 4.41Å; F289-I340 HydrophobicContact CD1-CD1 3.91Å; F289-I340 HydrophobicContact CE1-CD1 3.61Å; F289-I340 HydrophobicContact CG-CD1 4.49Å; F289-I340 HydrophobicContact CZ-CD1 3.98Å; I336-I340 HydrophobicContact CG2-CD1 4.2Å; I336-I340 WeakPolarHBondContact O-CG1 3.29Å; I336-I340 PolarHBondContact O-N 3.37Å; G337-I340 PolarHBondContact O-N 3.33Å; I340-L342 VanDerWaalsContact C-N 3.3Å; I340-L342 PolarHBondContact O-N 3.19Å; I340-F343 PolarHBondContact O-N 3.04Å; I340-I344 HydrophobicContact CG2-CG1 4.3Å; I340-I344 VanDerWaalsContact O-CG1 3.31Å; I340-I344 WeakPolarHBondContact O-CG1 3.22Å; I340-I344 PolarHBondContact O-N 3.14Å
341	W	93.1	Very high	84	Confident	5 Å²	5	40.8 Å²	40.8	2%	0.019	21%	0.212	C	C	.	.	H	α-helix	trans	-54	-45.8	174.5	167.8	95.8	0	0	0	112.3	L47 I48 T51 F179 G337 M338 F343 I344 V345 A408 Y411 V412	L47-W341 HydrophobicContact CD1-CZ2 4.21Å; L47-W341 HydrophobicContact CD2-CH2 4.19Å; L47-W341 HydrophobicContact CD2-CZ2 3.57Å; L47-W341 HydrophobicContact CG-CH2 3.91Å; L47-W341 HydrophobicContact CG-CZ2 3.64Å; I48-W341 HydrophobicContact CG1-CH2 4.46Å; T51-W341 HydrophobicContact CG2-CH2 4.21Å; T51-W341 HydrophobicContact CG2-CZ3 4.1Å; T51-W341 VanDerWaalsContact OG1-CH2 3.3Å; T51-W341 WeakPolarHBondContact OG1-CH2 3.31Å; F179-W341 AromaticContact CE1-CD1 3.4Å; F179-W341 VanDerWaalsContact CE1-CD1 3.4Å; F179-W341 HydrophobicContact CE1-CG 4.47Å; F179-W341 AromaticContact CZ-CD1 3.65Å; F179-W341 AromaticContact CZ-NE1 3.94Å; G337-W341 WeakPolarHBondContact O-CB 3.38Å; G337-W341 PolarHBondContact O-N 3.48Å; M338-W341 HydrophobicContact CE-CD2 4.26Å; M338-W341 HydrophobicContact CE-CE3 3.85Å; M338-W341 HydrophobicContact CE-CZ3 4.17Å; M338-W341 WeakPolarHBondContact O-CB 3.24Å; M338-W341 PolarHBondContact O-N 3.33Å; W341-F343 PolarHBondContact O-N 3.36Å; W341-I344 PolarHBondContact O-N 3.41Å; W341-V345 HydrophobicContact CD2-CG2 4.1Å; W341-V345 HydrophobicContact CG-CG2 4.41Å; W341-V345 HydrophobicContact CZ2-CG2 4.02Å; W341-V345 WeakPolarHBondContact O-CG2 3.32Å; W341-V345 PolarHBondContact O-N 3.25Å; W341-A408 PolarHBondContact NE1-O 2.86Å; W341-Y411 HydrophobicContact CB-CD1 4.2Å; W341-Y411 HydrophobicContact CB-CE1 3.73Å; W341-Y411 AromaticContact CD1-CD1 3.43Å; W341-Y411 VanDerWaalsContact CD1-CD1 3.43Å; W341-Y411 AromaticContact CD1-CE1 3.88Å; W341-Y411 HydrophobicContact CG-CD1 4.02Å; W341-Y411 HydrophobicContact CG-CE1 4.06Å; W341-V412 HydrophobicContact CD2-CG2 3.97Å; W341-V412 HydrophobicContact CE3-CG2 4.44Å; W341-V412 HydrophobicContact CH2-CG2 3.93Å; W341-V412 HydrophobicContact CZ2-CG2 3.34Å; W341-V412 HydrophobicContact CZ3-CG2 4.43Å
342	L	92	Very high	83.1	Confident	60 Å²	60	41.3 Å²	41.3	31%	0.314	22%	0.215	S	C	.	.	H	α-helix	trans	-59.9	-46.8	179.4	177.5	65.3	0	0	0	111.3	I48 M338 V339 I340 I344 V345 L346	I48-L342 HydrophobicContact CD1-CD1 3.53Å; I48-L342 HydrophobicContact CG1-CD1 3.65Å; I48-L342 HydrophobicContact CG2-CD1 4.45Å; M338-L342 PolarHBondContact O-N 3.15Å; V339-L342 WeakPolarHBondContact O-CB 3.33Å; V339-L342 PolarHBondContact O-N 3.41Å; I340-L342 VanDerWaalsContact C-N 3.3Å; I340-L342 PolarHBondContact O-N 3.19Å; L342-I344 VanDerWaalsContact C-N 3.31Å; L342-I344 PolarHBondContact O-N 3.46Å; L342-V345 PolarHBondContact O-N 2.98Å; L342-L346 HydrophobicContact CD1-CD1 4.29Å; L342-L346 HydrophobicContact CD1-CG 4.49Å; L342-L346 HydrophobicContact CG-CD1 4.25Å; L342-L346 VanDerWaalsContact O-CG 3.29Å; L342-L346 WeakPolarHBondContact O-CG 3.34Å; L342-L346 PolarHBondContact O-N 3.02Å; L342-L346 VanDerWaalsContact O-N 3.09Å
343	F	90.5	Very high	81.7	Confident	136 Å²	136	40.1 Å²	40.1	60%	0.596	21%	0.207	S	C	*	.	H	α-helix	trans	-61.6	-40.3	177.2	-75.4	-63.3	0	0	0	112.1	V339 I340 W341 Y347	V339-F343 HydrophobicContact CG1-CD2 3.85Å; V339-F343 HydrophobicContact CG1-CE2 3.46Å; V339-F343 VanDerWaalsContact CG1-CE2 3.46Å; V339-F343 WeakPolarHBondContact O-CD2 3.33Å; V339-F343 PolarHBondContact O-N 2.93Å; V339-F343 VanDerWaalsContact O-N 3.14Å; I340-F343 PolarHBondContact O-N 3.04Å; W341-F343 PolarHBondContact O-N 3.36Å; F343-Y347 VanDerWaalsContact O-CB 3.22Å; F343-Y347 WeakPolarHBondContact O-CB 3.33Å; F343-Y347 PolarHBondContact O-N 3.4Å
344	I	89.3	Confident	79.8	Confident	6 Å²	6	43.5 Å²	43.5	3%	0.031	23%	0.228	C	C	.	.	H	α-helix	trans	-71.2	-39.3	-178.9	-67.1	-71.7	0	0	0	112	Q183 L186 L187 I340 W341 L342 Y347 T348	Q183-I344 HydrophobicContact CG-CB 4.39Å; Q183-I344 HydrophobicContact CG-CG1 3.97Å; Q183-I344 HydrophobicContact CG-CG2 4.2Å; L186-I344 HydrophobicContact CB-CD1 4.27Å; L186-I344 HydrophobicContact CB-CG2 3.99Å; L186-I344 HydrophobicContact CD1-CG2 3.6Å; L186-I344 HydrophobicContact CG-CG2 4.47Å; L187-I344 HydrophobicContact CB-CD1 4.23Å; L187-I344 HydrophobicContact CD1-CD1 3.98Å; I340-I344 HydrophobicContact CG2-CG1 4.3Å; I340-I344 VanDerWaalsContact O-CG1 3.31Å; I340-I344 WeakPolarHBondContact O-CG1 3.22Å; I340-I344 PolarHBondContact O-N 3.14Å; W341-I344 PolarHBondContact O-N 3.41Å; L342-I344 VanDerWaalsContact C-N 3.31Å; L342-I344 PolarHBondContact O-N 3.46Å; I344-Y347 PolarHBondContact O-N 3.29Å; I344-T348 WeakPolarHBondContact O-CB 3.47Å; I344-T348 PolarHBondContact O-N 3.32Å; I344-T348 PolarHBondContact O-OG1 3.43Å
345	V	87.4	Confident	77.6	Confident	5 Å²	5	47.4 Å²	47.4	3%	0.03	26%	0.26	C	S	.	.	H	α-helix	trans	-62.2	-46	174.6	168.7	0	0	0	0	110.7	L47 W341 L342 Y347 T348 C349 F405	L47-V345 HydrophobicContact CD2-CG1 4.24Å; L47-V345 HydrophobicContact CD2-CG2 4.34Å; W341-V345 HydrophobicContact CD2-CG2 4.1Å; W341-V345 HydrophobicContact CG-CG2 4.41Å; W341-V345 HydrophobicContact CZ2-CG2 4.02Å; W341-V345 WeakPolarHBondContact O-CG2 3.32Å; W341-V345 PolarHBondContact O-N 3.25Å; L342-V345 PolarHBondContact O-N 2.98Å; V345-Y347 VanDerWaalsContact C-N 3.34Å; V345-Y347 PolarHBondContact O-N 3.44Å; V345-T348 PolarHBondContact O-N 2.86Å; V345-C349 PolarHBondContact O-N 3.47Å; V345-C349 PolarHBondContact O-SG 3.19Å; V345-F405 HydrophobicContact CG1-CZ 4.28Å
346	L	85.3	Confident	75.4	Confident	57 Å²	57	45.2 Å²	45.2	30%	0.298	26%	0.257	S	S	.	.	H	α-helix	trans	-63.1	-42.1	175.6	-68.6	174	0	0	0	111.5	I48 L342 T348 C349 L350	I48-L346 HydrophobicContact CD1-CD2 4.14Å; L342-L346 HydrophobicContact CD1-CD1 4.29Å; L342-L346 HydrophobicContact CD1-CG 4.49Å; L342-L346 HydrophobicContact CG-CD1 4.25Å; L342-L346 VanDerWaalsContact O-CG 3.29Å; L342-L346 WeakPolarHBondContact O-CG 3.34Å; L342-L346 PolarHBondContact O-N 3.02Å; L342-L346 VanDerWaalsContact O-N 3.09Å; L346-T348 PolarHBondContact O-N 3.4Å; L346-C349 PolarHBondContact O-N 3.06Å; L346-L350 WeakPolarHBondContact O-CG 3.33Å; L346-L350 PolarHBondContact O-N 3.4Å
347	Y	83.7	Confident	73	Confident	29 Å²	29	42.3 Å²	42.3	11%	0.114	24%	0.243	C	C	.	.	H	α-helix	trans	-60.9	-43	177.1	-179.1	-111.7	0	0	0	112.4	F190 F343 I344 V345 C349 L350 R351	F190-Y347 WeakPolarHBondContact CA-OH 3.14Å; F190-Y347 HydrophobicContact CB-CD1 4.31Å; F190-Y347 HydrophobicContact CB-CE1 3.82Å; F190-Y347 HydrophobicContact CB-CE2 4.33Å; F190-Y347 AromaticContact CD2-CD2 3.83Å; F190-Y347 HydrophobicContact CD2-CD2 3.83Å; F190-Y347 AromaticContact CD2-CE2 3.62Å; F190-Y347 HydrophobicContact CD2-CE2 3.62Å; F190-Y347 HydrophobicContact CD2-CG 4.39Å; F190-Y347 AromaticContact CD2-CZ 3.98Å; F190-Y347 HydrophobicContact CE2-CE2 4.5Å; F190-Y347 HydrophobicContact CG-CE2 4.47Å; F343-Y347 VanDerWaalsContact O-CB 3.22Å; F343-Y347 WeakPolarHBondContact O-CB 3.33Å; F343-Y347 PolarHBondContact O-N 3.4Å; I344-Y347 PolarHBondContact O-N 3.29Å; V345-Y347 VanDerWaalsContact C-N 3.34Å; V345-Y347 PolarHBondContact O-N 3.44Å; Y347-C349 VanDerWaalsContact C-N 3.26Å; Y347-C349 PolarHBondContact O-N 3.49Å; Y347-L350 PolarHBondContact O-N 3.24Å; Y347-L350 VanDerWaalsContact O-N 3.14Å; Y347-R351 HydrophobicContact CE1-CB 4.21Å; Y347-R351 HydrophobicContact CE1-CG 4.47Å; Y347-R351 HydrophobicContact CE2-CB 4.34Å; Y347-R351 WeakPolarHBondContact O-CB 3.47Å; Y347-R351 PolarHBondContact O-N 2.99Å; Y347-R351 WeakPolarHBondContact OH-CD 3.46Å; Y347-R351 PolarHBondContact OH-NH1 3.07Å
348	T	79.1	Confident	70.4	Confident	6 Å²	6	43.9 Å²	43.9	4%	0.037	26%	0.256	C	S	.	.	H	α-helix	trans	-58.2	-40.4	178.3	-58.1	0	0	0	0	111.6	L186 I344 V345 L346 T352	L186-T348 WeakPolarHBondContact CD1-OG1 3.37Å; I344-T348 WeakPolarHBondContact O-CB 3.47Å; I344-T348 PolarHBondContact O-N 3.32Å; I344-T348 PolarHBondContact O-OG1 3.43Å; V345-T348 PolarHBondContact O-N 2.86Å; L346-T348 PolarHBondContact O-N 3.4Å; T348-T352 WeakPolarHBondContact O-CB 3.09Å; T348-T352 PolarHBondContact O-N 3.27Å; T348-T352 PolarHBondContact O-OG1 3.29Å
349	C	76.1	Confident	67.9	Low	4 Å²	4	48.6 Å²	48.6	3%	0.027	28%	0.277	C	S	.	.	H	α-helix	trans	-68.6	-38.4	178.4	-68.1	0	0	0	0	112.6	R40 S44 V345 L346 Y347 S353	R40-C349 HydrophobicContact CB-CB 4.32Å; S44-C349 PolarHBondContact OG-SG 2.86Å; V345-C349 PolarHBondContact O-N 3.47Å; V345-C349 PolarHBondContact O-SG 3.19Å; L346-C349 PolarHBondContact O-N 3.06Å; Y347-C349 VanDerWaalsContact C-N 3.26Å; Y347-C349 PolarHBondContact O-N 3.49Å; C349-S353 PolarHBondContact O-OG 2.64Å
350	L	71.2	Confident	65.3	Low	100 Å²	100	52.4 Å²	52.4	52%	0.524	29%	0.288	S	S	.	.	H	α-helix	trans	-73.1	-47.1	177.8	-64.9	174.5	0	0	0	111.5	L346 Y347 S353	L346-L350 WeakPolarHBondContact O-CG 3.33Å; L346-L350 PolarHBondContact O-N 3.4Å; Y347-L350 PolarHBondContact O-N 3.24Å; Y347-L350 VanDerWaalsContact O-N 3.14Å; L350-S353 WeakPolarHBondContact O-CB 3.33Å; L350-S353 PolarHBondContact O-N 2.97Å; L350-S353 PolarHBondContact O-OG 3.1Å; L350-S353 VanDerWaalsContact O-OG 3.1Å
351	R	68.1	Low	62.5	Low	35 Å²	35	57.2 Å²	57.2	13%	0.132	31%	0.311	C	S	.	.	H	α-helix	trans	-67	-41	-172.8	-172.9	-179.8	-175.9	128.6	-2.3	113.2	D189 S193 Y347 S353 T354 A357	D189-R351 VanDerWaalsContact C-NH1 3.32Å; D189-R351 PolarHBondContact O-NH1 3.48Å; D189-R351 IonicContact OD1-CZ 3.67Å; D189-R351 IonicContact OD1-NE 2.66Å; D189-R351 IonicContact OD1-NH1 3.16Å; D189-R351 PolarHBondContact OD1-NH1 2.75Å; D189-R351 IonicContact OD1-NH2 3.85Å; D189-R351 PolarHBondContact OD1-NH2 3.41Å; D189-R351 WeakPolarHBondContact OD2-CD 3.22Å; D189-R351 IonicContact OD2-CZ 3.94Å; D189-R351 IonicContact OD2-NE 2.82Å; D189-R351 PolarHBondContact OD2-NE 3.37Å; D189-R351 IonicContact OD2-NH1 2.93Å; D189-R351 PolarHBondContact OD2-NH1 2.82Å; D189-R351 IonicContact OD2-NH2 3.7Å; D189-R351 PolarHBondContact OD2-NH2 3.01Å; S193-R351 PolarHBondContact OG-NH1 2.85Å; Y347-R351 HydrophobicContact CE1-CB 4.21Å; Y347-R351 HydrophobicContact CE1-CG 4.47Å; Y347-R351 HydrophobicContact CE2-CB 4.34Å; Y347-R351 WeakPolarHBondContact O-CB 3.47Å; Y347-R351 PolarHBondContact O-N 2.99Å; Y347-R351 WeakPolarHBondContact OH-CD 3.46Å; Y347-R351 PolarHBondContact OH-NH1 3.07Å; R351-S353 PolarHBondContact O-N 3.34Å; R351-T354 PolarHBondContact O-N 3.43Å; R351-T354 VanDerWaalsContact O-N 3.12Å; R351-A357 HydrophobicContact CG-CB 4.05Å
352	T	54	Low	59.7	Low	28 Å²	28	60.5 Å²	60.5	17%	0.172	34%	0.339	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.1	-10.6	179.9	-48.2	0	0	0	0	111.8	R40 T348 Y396	R40-T352 PolarHBondContact NH1-O 2.97Å; T348-T352 WeakPolarHBondContact O-CB 3.09Å; T348-T352 PolarHBondContact O-N 3.27Å; T348-T352 PolarHBondContact O-OG1 3.29Å; T352-Y396 VanDerWaalsContact CG2-CB 3.4Å; T352-Y396 HydrophobicContact CG2-CD1 4.12Å; T352-Y396 HydrophobicContact CG2-CD2 4.37Å; T352-Y396 HydrophobicContact CG2-CG 3.72Å
353	S	45.8	Very low	56.8	Low	40 Å²	40	63.8 Å²	63.8	28%	0.28	36%	0.357	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.6	-19.4	179.2	-45.9	0	0	0	0	113.8	V37 R40 C349 L350 R351	V37-S353 WeakPolarHBondContact CG2-OG 3.28Å; R40-S353 PolarHBondContact NH2-OG 3.43Å; C349-S353 PolarHBondContact O-OG 2.64Å; L350-S353 WeakPolarHBondContact O-CB 3.33Å; L350-S353 PolarHBondContact O-N 2.97Å; L350-S353 PolarHBondContact O-OG 3.1Å; L350-S353 VanDerWaalsContact O-OG 3.1Å; R351-S353 PolarHBondContact O-N 3.34Å
354	T	41.7	Very low	54	Low	79 Å²	79	67.5 Å²	67.5	49%	0.485	37%	0.373	S	S	.	.	S	Bend	trans	-90	119.4	-178.2	-41.9	0	0	0	0	108.3	R351 S356 A357	R351-T354 PolarHBondContact O-N 3.43Å; R351-T354 VanDerWaalsContact O-N 3.12Å; T354-S356 WeakPolarHBondContact CG2-OG 3.32Å; T354-S356 PolarHBondContact O-N 2.95Å; T354-A357 PolarHBondContact O-N 3.47Å
355	A	37.7	Very low	51.1	Low	88 Å²	88	72.6 Å²	72.6	73%	0.727	41%	0.409	S	S	*	.	H	α-helix	trans	-47.9	-24.6	-176.2	0	0	0	0	0	114.6
356	S	38.1	Very low	48.3	Very low	70 Å²	70	75.5 Å²	75.5	49%	0.49	44%	0.44	S	S	.	.	H	α-helix	trans	-77	-13.6	179.6	38.1	0	0	0	0	116.3	T354	T354-S356 WeakPolarHBondContact CG2-OG 3.32Å; T354-S356 PolarHBondContact O-N 2.95Å
357	A	39	Very low	45.4	Very low	9 Å²	9	80.9 Å²	80.9	7%	0.074	47%	0.469	C	S	.	.	H	α-helix	trans	-94.2	-30.8	179.2	0	0	0	0	0	113.7	R351 T354 E359 K360 M361	R351-A357 HydrophobicContact CG-CB 4.05Å; T354-A357 PolarHBondContact O-N 3.47Å; A357-E359 VanDerWaalsContact C-N 3.28Å; A357-K360 PolarHBondContact O-N 3.09Å; A357-M361 PolarHBondContact O-N 3.47Å; A357-M361 VanDerWaalsContact O-N 3.13Å
358	A	34.7	Very low	43	Very low	36 Å²	36	86.1 Å²	86.1	30%	0.298	50%	0.504	S	S	.	.	H	α-helix	trans	-66.6	-34.4	172.1	0	0	0	0	0	111	A362 T395	A358-A362 WeakPolarHBondContact O-CB 3.48Å; A358-A362 PolarHBondContact O-N 3.47Å; A358-T395 WeakPolarHBondContact CB-O 3.31Å
359	E	36.8	Very low	40.7	Very low	120 Å²	120	94 Å²	94	56%	0.561	55%	0.545	S	S	*	.	H	α-helix	trans	-63.3	-51.3	170.3	-128.9	175.2	174.7	0	0	110.6	A357 M361 A362 L363	A357-E359 VanDerWaalsContact C-N 3.28Å; E359-M361 VanDerWaalsContact C-N 3.28Å; E359-M361 PolarHBondContact O-N 3.26Å; E359-A362 PolarHBondContact O-N 3.49Å; E359-L363 HydrophobicContact CG-CD1 4.34Å; E359-L363 WeakPolarHBondContact O-CB 3.19Å; E359-L363 PolarHBondContact O-N 3.4Å
360	K	36.9	Very low	38.4	Very low	157 Å²	157	101.5 Å²	101.5	68%	0.683	58%	0.584	S	S	*	*	H	α-helix	trans	-66.6	-20.7	-178.5	-72.9	-173.1	177.2	-172.7	0	115.3	A357	A357-K360 PolarHBondContact O-N 3.09Å
361	M	32.6	Very low	36.5	Very low	131 Å²	131	104.2 Å²	104.2	65%	0.645	60%	0.599	S	S	*	*	H	α-helix	trans	-103	-11.4	175.5	-70.9	-154.4	-81.1	0	0	115.3	A357 E359	A357-M361 PolarHBondContact O-N 3.47Å; A357-M361 VanDerWaalsContact O-N 3.13Å; E359-M361 VanDerWaalsContact C-N 3.28Å; E359-M361 PolarHBondContact O-N 3.26Å
362	A	34.3	Very low	34.6	Very low	74 Å²	74	111.6 Å²	111.6	61%	0.612	63%	0.634	S	S	*	*	H	α-helix	trans	-114.5	-9.6	177.6	0	0	0	0	0	114.3	A358 E359 K364	A358-A362 WeakPolarHBondContact O-CB 3.48Å; A358-A362 PolarHBondContact O-N 3.47Å; E359-A362 PolarHBondContact O-N 3.49Å; A362-K364 VanDerWaalsContact C-N 3.28Å; A362-K364 PolarHBondContact O-N 3.21Å
363	L	31	Very low	33.4	Very low	129 Å²	129	113.5 Å²	113.5	68%	0.675	66%	0.66	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.2	70.1	-175.9	-160.2	77.2	0	0	0	112.3	E359	E359-L363 HydrophobicContact CG-CD1 4.34Å; E359-L363 WeakPolarHBondContact O-CB 3.19Å; E359-L363 PolarHBondContact O-N 3.4Å
364	K	31.2	Very low	32.6	Very low	214 Å²	214	117 Å²	117	93%	0.93	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-134.8	12.7	152	-130	-176.8	-173.8	-177.5	0	113.3	A362	A362-K364 VanDerWaalsContact C-N 3.28Å; A362-K364 PolarHBondContact O-N 3.21Å
365	S	28.6	Very low	31.8	Very low	113 Å²	113	121 Å²	121	79%	0.79	70%	0.7	S	S	*	*	S	Bend	trans	-152	105.4	178.3	179.2	0	0	0	0	113
366	G	28.9	Very low	31.4	Very low	67 Å²	67	120.2 Å²	120.2	69%	0.691	70%	0.701	S	S	*	*			trans	112.1	112	150	0	0	0	0	0	116.6	T368	G366-T368 PolarHBondContact O-N 3.3Å
367	N	25	Very low	30.8	Very low	169 Å²	169	125.6 Å²	125.6	90%	0.904	72%	0.718	S	S	*	*			trans	-51.6	124	168.3	-70.6	-19.7	0	0	0	112.7
368	T	32	Very low	30.2	Very low	139 Å²	139	133.1 Å²	133.1	85%	0.853	76%	0.757	S	S	*	*			trans	-144.3	110.5	151.8	40.5	0	0	0	0	111.4	G366	G366-T368 PolarHBondContact O-N 3.3Å
369	L	31	Very low	30	Very low	172 Å²	172	136.1 Å²	136.1	90%	0.901	78%	0.782	S	S	*	*			trans	-22.9	122.5	164.8	-60.5	162	0	0	0	116.2
370	I	28.7	Very low	29.5	Very low	162 Å²	162	135.5 Å²	135.5	83%	0.831	80%	0.797	S	S	*	*			trans	-75.7	115.8	158.2	-41	168.1	0	0	0	105.7
371	N	29.6	Very low	29	Very low	157 Å²	157	132.7 Å²	132.7	84%	0.84	80%	0.803	S	S	*	*			trans	-117.4	101.7	168.5	-131.8	12.4	0	0	0	107.6
372	E	28.1	Very low	28.8	Very low	189 Å²	189	132.2 Å²	132.2	88%	0.883	80%	0.804	S	S	*	*			trans	-66.9	127.2	164.2	-67.7	-173.7	132.6	0	0	108.6
373	G	29.3	Very low	28.5	Very low	69 Å²	69	131.4 Å²	131.4	71%	0.711	80%	0.802	S	S	*	*			trans	-144	125.4	174.1	0	0	0	0	0	109.8
374	P	29.1	Very low	28.6	Very low	113 Å²	113	130.2 Å²	130.2	73%	0.734	81%	0.811	S	S	*	*			trans	-85.2	168.1	-169.2	35.7	-35	0	0	0	112.3
375	N	25.3	Very low	28.7	Very low	162 Å²	162	129.3 Å²	129.3	87%	0.866	80%	0.802	S	S	*	*			trans	89.8	114	165.8	-54.7	-24.7	0	0	0	117.4
376	G	29.5	Very low	29.4	Very low	72 Å²	72	127.1 Å²	127.1	74%	0.742	78%	0.783	S	S	*	*			trans	-176.7	38.9	169.8	0	0	0	0	0	113.3
377	E	26	Very low	30.4	Very low	184 Å²	184	131.1 Å²	131.1	86%	0.86	78%	0.778	S	S	*	*			trans	-54	135.6	154.9	-73.2	174.5	128	0	0	107.6
378	N	26.6	Very low	31.9	Very low	167 Å²	167	126.8 Å²	126.8	89%	0.893	76%	0.755	S	S	*	*			trans	108.6	68.5	-179.4	-51.5	-32.9	0	0	0	115.7
379	A	30.3	Very low	33.3	Very low	99 Å²	99	123.1 Å²	123.1	82%	0.818	73%	0.73	S	S	*	*			trans	-140.2	21.2	162.3	0	0	0	0	0	113.9	A381	A379-A381 PolarHBondContact O-N 2.99Å
380	A	25.4	Very low	34.8	Very low	107 Å²	107	115 Å²	115	88%	0.884	69%	0.687	S	S	*	*	S	Bend	trans	-94.6	56.5	176.7	0	0	0	0	0	111.6
381	A	27	Very low	36.2	Very low	98 Å²	98	109.6 Å²	109.6	81%	0.81	66%	0.664	S	S	*	*	S	Bend	trans	-178.6	64.2	166.8	0	0	0	0	0	112.3	A379	A379-A381 PolarHBondContact O-N 2.99Å
382	D	27.9	Very low	37.7	Very low	121 Å²	121	111.4 Å²	111.4	65%	0.647	67%	0.668	S	S	*	*	S	Bend	trans	-155.8	138	154.8	-158.8	12.6	0	0	0	110.4	A384 R385	D382-A384 PolarHBondContact O-N 2.82Å; D382-R385 IonicContact OD2-CZ 3.07Å; D382-R385 VanDerWaalsContact OD2-CZ 3.3Å; D382-R385 IonicContact OD2-NE 2.59Å; D382-R385 IonicContact OD2-NH2 2.94Å; D382-R385 PolarHBondContact OD2-NH2 3.36Å
383	G	28.5	Very low	39.5	Very low	57 Å²	57	103.9 Å²	103.9	59%	0.588	64%	0.64	S	S	*	*			trans	-58.7	126.9	-164.9	0	0	0	0	0	114.8	R385	G383-R385 VanDerWaalsContact O-CG 3.28Å; G383-R385 WeakPolarHBondContact O-CG 3.17Å; G383-R385 PolarHBondContact O-N 2.91Å
384	A	32	Very low	41.4	Very low	104 Å²	104	102.3 Å²	102.3	86%	0.86	62%	0.617	S	S	*	*			trans	13.1	67.6	159.1	0	0	0	0	0	117.8	D382	D382-A384 PolarHBondContact O-N 2.82Å
385	R	35	Very low	43.2	Very low	194 Å²	194	98.9 Å²	98.9	73%	0.732	59%	0.594	S	S	*	*	P	Polyproline II helix	trans	-91.3	123.7	171.7	-57.4	-169.6	-171.8	179.6	3.1	110.1	D382 G383 W387	D382-R385 IonicContact OD2-CZ 3.07Å; D382-R385 VanDerWaalsContact OD2-CZ 3.3Å; D382-R385 IonicContact OD2-NE 2.59Å; D382-R385 IonicContact OD2-NH2 2.94Å; D382-R385 PolarHBondContact OD2-NH2 3.36Å; G383-R385 VanDerWaalsContact O-CG 3.28Å; G383-R385 WeakPolarHBondContact O-CG 3.17Å; G383-R385 PolarHBondContact O-N 2.91Å; R385-W387 PolarHBondContact O-N 3.49Å
386	V	43.3	Very low	45.4	Very low	67 Å²	67	92.1 Å²	92.1	41%	0.406	56%	0.556	S	S	.	*	P	Polyproline II helix	trans	-60.1	121.7	168.1	176.2	0	0	0	0	108
387	W	48.5	Very low	47.7	Very low	152 Å²	152	93.2 Å²	93.2	58%	0.576	55%	0.545	S	S	*	.	P	Polyproline II helix	trans	-74.2	129.1	179.4	55.2	69.2	0	0	0	111	R385	R385-W387 PolarHBondContact O-N 3.49Å
388	D	56.5	Low	50.4	Low	77 Å²	77	84.5 Å²	84.5	41%	0.412	51%	0.505	S	S	.	.			trans	-84.7	108.2	168.1	-177.7	16.4	0	0	0	108.9	S114 E390	S114-D388 PolarHBondContact OG-OD2 3.33Å; S114-D388 VanDerWaalsContact OG-OD2 3.08Å; D388-E390 VanDerWaalsContact C-N 3.34Å; D388-E390 PolarHBondContact OD1-N 3.25Å; D388-E390 VanDerWaalsContact OD1-N 3.15Å
389	N	62.6	Low	53.1	Low	62 Å²	62	77.3 Å²	77.3	33%	0.332	47%	0.467	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.2	11	-178.8	69.6	-32.6	0	0	0	113.7	S36	S36-N389 PolarHBondContact OG-ND2 3.47Å; S36-N389 PolarHBondContact OG-OD1 3.36Å
390	E	61	Low	55.7	Low	1 Å²	1	77 Å²	77	1%	0.005	45%	0.448	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.2	15.8	-176.4	-57.8	-166.3	135.9	0	0	113.8	S114 D388 E392 G393 T395 Y398	S114-E390 VanDerWaalsContact CB-O 3.27Å; S114-E390 WeakPolarHBondContact CB-O 3.38Å; S114-E390 PolarHBondContact N-O 2.74Å; S114-E390 PolarHBondContact OG-O 3.44Å; S114-E390 VanDerWaalsContact OG-O 3.07Å; D388-E390 VanDerWaalsContact C-N 3.34Å; D388-E390 PolarHBondContact OD1-N 3.25Å; D388-E390 VanDerWaalsContact OD1-N 3.15Å; E390-E392 PolarHBondContact O-N 2.98Å; E390-G393 CarbonylContact C-O 3.51Å; E390-G393 VanDerWaalsContact CA-O 3.3Å; E390-G393 WeakPolarHBondContact CA-O 3.48Å; E390-G393 PolarHBondContact O-N 2.88Å; E390-T395 HydrophobicContact CG-CG2 4Å; E390-T395 PolarHBondContact OE1-N 3.43Å; E390-T395 PolarHBondContact OE1-OG1 2.86Å; E390-Y398 PolarHBondContact OE2-OH 2.99Å
391	S	57.7	Low	58.5	Low	50 Å²	50	72.2 Å²	72.2	35%	0.35	41%	0.407	S	S	.	.	S	Bend	trans	-67.1	-32.8	-173	63.3	0	0	0	0	114.2	S114	S114-S391 WeakPolarHBondContact OG-CA 3.38Å
392	E	61.6	Low	61.5	Low	195 Å²	195	67.6 Å²	67.6	91%	0.911	37%	0.368	S	S	*	.	S	Bend	trans	-95.4	-22.6	178.2	-63.6	-171.4	167.4	0	0	113	E390	E390-E392 PolarHBondContact O-N 2.98Å
393	G	66	Low	64.4	Low	30 Å²	30	65 Å²	65	31%	0.309	35%	0.352	S	S	.	.	S	Bend	trans	-178.2	151.4	179	0	0	0	0	0	111.1	E390	E390-G393 CarbonylContact C-O 3.51Å; E390-G393 VanDerWaalsContact CA-O 3.3Å; E390-G393 WeakPolarHBondContact CA-O 3.48Å; E390-G393 PolarHBondContact O-N 2.88Å
394	V	69.9	Low	67.3	Low	36 Å²	36	63.2 Å²	63.2	22%	0.218	33%	0.329	C	S	.	.			trans	-68.4	134.6	176.9	-66	0	0	0	0	110.8	V111 R112 Y396 Y398	V111-V394 HydrophobicContact CG1-CG1 4.39Å; R112-V394 PolarHBondContact O-N 3.01Å; V394-Y396 WeakPolarHBondContact CG2-O 3.12Å; V394-Y396 PolarHBondContact O-N 3.19Å; V394-Y398 HydrophobicContact CB-CE1 4.05Å; V394-Y398 HydrophobicContact CG1-CE1 3.9Å; V394-Y398 HydrophobicContact CG1-CE2 3.96Å
395	T	67	Low	70.1	Confident	42 Å²	42	58.3 Å²	58.3	26%	0.258	29%	0.288	S	S	.	.	S	Bend	trans	-71.8	-19	-178.9	55.9	0	0	0	0	112.9	A358 E390	A358-T395 WeakPolarHBondContact CB-O 3.31Å; E390-T395 HydrophobicContact CG-CG2 4Å; E390-T395 PolarHBondContact OE1-N 3.43Å; E390-T395 PolarHBondContact OE1-OG1 2.86Å
396	Y	70.1	Confident	73	Confident	19 Å²	19	50.4 Å²	50.4	8%	0.075	26%	0.259	C	S	.	.	S	Bend	trans	-150.2	159.1	176.1	64.7	-78.3	0	0	0	110.2	R40 T352 V394 Y398 F401	R40-Y396 HydrophobicContact CG-CE1 4.29Å; R40-Y396 HydrophobicContact CG-CE2 4.39Å; T352-Y396 VanDerWaalsContact CG2-CB 3.4Å; T352-Y396 HydrophobicContact CG2-CD1 4.12Å; T352-Y396 HydrophobicContact CG2-CD2 4.37Å; T352-Y396 HydrophobicContact CG2-CG 3.72Å; V394-Y396 WeakPolarHBondContact CG2-O 3.12Å; V394-Y396 PolarHBondContact O-N 3.19Å; Y396-Y398 HydrophobicContact CD1-CE1 4.43Å; Y396-Y398 HydrophobicContact CD2-CD1 4.03Å; Y396-Y398 HydrophobicContact CE1-CD1 4.03Å; Y396-Y398 AromaticContact CE1-CE1 3.83Å; Y396-Y398 HydrophobicContact CE1-CE1 3.83Å; Y396-Y398 AromaticContact CE2-CD1 3.54Å; Y396-Y398 HydrophobicContact CE2-CD1 3.54Å; Y396-Y398 HydrophobicContact CE2-CE1 4.19Å; Y396-Y398 HydrophobicContact CE2-CG 4.5Å; Y396-Y398 HydrophobicContact CG-CD1 4.48Å; Y396-Y398 AromaticContact CZ-CD1 3.51Å; Y396-Y398 AromaticContact CZ-CE1 3.68Å; Y396-Y398 WeakPolarHBondContact O-CD1 3.23Å; Y396-Y398 PolarHBondContact O-N 3.47Å; Y396-Y398 VanDerWaalsContact O-N 3.14Å; Y396-F401 HydrophobicContact CD2-CB 3.73Å; Y396-F401 HydrophobicContact CD2-CG 4.27Å; Y396-F401 HydrophobicContact CE2-CB 3.56Å; Y396-F401 HydrophobicContact CE2-CD1 4.25Å; Y396-F401 HydrophobicContact CE2-CD2 4.22Å; Y396-F401 AromaticContact CE2-CG 3.75Å; Y396-F401 HydrophobicContact CE2-CG 3.75Å
397	N	78.9	Confident	75.3	Confident	96 Å²	96	47.4 Å²	47.4	51%	0.513	24%	0.24	S	C	.	.			trans	-73.1	108.2	173.7	-174.8	-25.2	0	0	0	110	S399 F400 F401	N397-S399 VanDerWaalsContact C-N 3.26Å; N397-S399 PolarHBondContact O-N 3.22Å; N397-S399 WeakPolarHBondContact OD1-CB 3.29Å; N397-S399 PolarHBondContact OD1-N 3.14Å; N397-F400 HydrophobicContact CB-CB 3.99Å; N397-F400 PolarHBondContact O-N 3.2Å; N397-F400 VanDerWaalsContact O-N 3.12Å; N397-F400 PolarHBondContact OD1-N 3.09Å; N397-F401 PolarHBondContact O-N 3.17Å; N397-F401 VanDerWaalsContact O-N 3.07Å
398	Y	81.6	Confident	77.4	Confident	1 Å²	1	40.2 Å²	40.2	0%	0.004	21%	0.213	C	C	.	.	H	α-helix	trans	-56.9	-37.7	-179.6	-64.9	-8.6	0	0	0	113.1	M108 V111 A119 Q122 N123 E390 V394 Y396 F401 H402	M108-Y398 HydrophobicContact SD-CD2 4.3Å; V111-Y398 HydrophobicContact CB-CD2 4.12Å; V111-Y398 HydrophobicContact CG1-CD2 3.84Å; V111-Y398 HydrophobicContact CG1-CE2 3.82Å; A119-Y398 HydrophobicContact CB-CE2 4.1Å; Q122-Y398 HydrophobicContact CB-CD2 4.34Å; Q122-Y398 HydrophobicContact CB-CE2 4.24Å; Q122-Y398 HydrophobicContact CG-CD2 4Å; Q122-Y398 HydrophobicContact CG-CE2 4Å; Q122-Y398 HydrophobicContact CG-CG 4.36Å; N123-Y398 PolarHBondContact ND2-OH 3.43Å; E390-Y398 PolarHBondContact OE2-OH 2.99Å; V394-Y398 HydrophobicContact CB-CE1 4.05Å; V394-Y398 HydrophobicContact CG1-CE1 3.9Å; V394-Y398 HydrophobicContact CG1-CE2 3.96Å; Y396-Y398 HydrophobicContact CD1-CE1 4.43Å; Y396-Y398 HydrophobicContact CD2-CD1 4.03Å; Y396-Y398 HydrophobicContact CE1-CD1 4.03Å; Y396-Y398 AromaticContact CE1-CE1 3.83Å; Y396-Y398 HydrophobicContact CE1-CE1 3.83Å; Y396-Y398 AromaticContact CE2-CD1 3.54Å; Y396-Y398 HydrophobicContact CE2-CD1 3.54Å; Y396-Y398 HydrophobicContact CE2-CE1 4.19Å; Y396-Y398 HydrophobicContact CE2-CG 4.5Å; Y396-Y398 HydrophobicContact CG-CD1 4.48Å; Y396-Y398 AromaticContact CZ-CD1 3.51Å; Y396-Y398 AromaticContact CZ-CE1 3.68Å; Y396-Y398 WeakPolarHBondContact O-CD1 3.23Å; Y396-Y398 PolarHBondContact O-N 3.47Å; Y396-Y398 VanDerWaalsContact O-N 3.14Å; Y398-F401 PolarHBondContact O-N 3.03Å; Y398-H402 PolarHBondContact O-CD2 2.97Å; Y398-H402 PolarHBondContact O-N 3.34Å
399	S	84.7	Confident	79.2	Confident	15 Å²	15	36.5 Å²	36.5	11%	0.105	19%	0.194	C	C	.	.	H	α-helix	trans	-65.5	-43	177.8	179.6	0	0	0	0	111.2	M105 L109 N397 F401 H402 F403	M105-S399 WeakPolarHBondContact CG-OG 3.44Å; M105-S399 PolarHBondContact O-OG 2.99Å; L109-S399 WeakPolarHBondContact CD2-OG 3.33Å; N397-S399 VanDerWaalsContact C-N 3.26Å; N397-S399 PolarHBondContact O-N 3.22Å; N397-S399 WeakPolarHBondContact OD1-CB 3.29Å; N397-S399 PolarHBondContact OD1-N 3.14Å; S399-F401 VanDerWaalsContact C-N 3.32Å; S399-F401 PolarHBondContact O-N 3.03Å; S399-H402 PolarHBondContact O-N 3.31Å; S399-F403 WeakPolarHBondContact O-CB 3.23Å; S399-F403 PolarHBondContact O-N 3.41Å
400	F	84	Confident	80.8	Confident	94 Å²	94	33.7 Å²	33.7	41%	0.412	18%	0.178	S	C	.	.	H	α-helix	trans	-66.7	-36.5	179.7	-174.7	-113	0	0	0	111.7	N397 F403 I404	N397-F400 HydrophobicContact CB-CB 3.99Å; N397-F400 PolarHBondContact O-N 3.2Å; N397-F400 VanDerWaalsContact O-N 3.12Å; N397-F400 PolarHBondContact OD1-N 3.09Å; F400-F403 HydrophobicContact CD2-CD1 4.2Å; F400-F403 HydrophobicContact CE2-CD1 4.23Å; F400-F403 WeakPolarHBondContact O-CB 3.38Å; F400-F403 PolarHBondContact O-N 3.28Å; F400-I404 HydrophobicContact CD1-CD1 3.96Å; F400-I404 HydrophobicContact CE1-CD1 3.63Å; F400-I404 HydrophobicContact CE1-CG1 4.24Å; F400-I404 HydrophobicContact CZ-CD1 4.13Å; F400-I404 HydrophobicContact CZ-CG1 4.3Å; F400-I404 WeakPolarHBondContact O-CG1 3.38Å; F400-I404 PolarHBondContact O-N 3.04Å
401	F	85.3	Confident	82.3	Confident	6 Å²	6	34.4 Å²	34.4	3%	0.026	18%	0.181	C	C	.	.	H	α-helix	trans	-59.3	-49.5	173.3	176.4	-97.2	0	0	0	112.2	R40 Y43 Y396 N397 Y398 S399 F403 I404 F405	R40-F401 HydrophobicContact CB-CE2 3.96Å; R40-F401 HydrophobicContact CB-CZ 3.77Å; R40-F401 HydrophobicContact CG-CD2 4.24Å; R40-F401 HydrophobicContact CG-CE1 4.22Å; R40-F401 HydrophobicContact CG-CE2 3.67Å; R40-F401 HydrophobicContact CG-CZ 3.67Å; Y43-F401 AromaticContact CD2-CE1 3.89Å; Y43-F401 HydrophobicContact CD2-CE1 3.89Å; Y43-F401 HydrophobicContact CG-CE1 4.24Å; Y396-F401 HydrophobicContact CD2-CB 3.73Å; Y396-F401 HydrophobicContact CD2-CG 4.27Å; Y396-F401 HydrophobicContact CE2-CB 3.56Å; Y396-F401 HydrophobicContact CE2-CD1 4.25Å; Y396-F401 HydrophobicContact CE2-CD2 4.22Å; Y396-F401 AromaticContact CE2-CG 3.75Å; Y396-F401 HydrophobicContact CE2-CG 3.75Å; N397-F401 PolarHBondContact O-N 3.17Å; N397-F401 VanDerWaalsContact O-N 3.07Å; Y398-F401 PolarHBondContact O-N 3.03Å; S399-F401 VanDerWaalsContact C-N 3.32Å; S399-F401 PolarHBondContact O-N 3.03Å; F401-F403 VanDerWaalsContact C-N 3.29Å; F401-F403 PolarHBondContact O-N 3.5Å; F401-I404 PolarHBondContact O-N 3.03Å; F401-F405 HydrophobicContact CD2-CD2 4.43Å; F401-F405 AromaticContact CD2-CE2 3.99Å; F401-F405 HydrophobicContact CD2-CE2 3.99Å; F401-F405 HydrophobicContact CE1-CD2 4.22Å; F401-F405 AromaticContact CE1-CE2 3.97Å; F401-F405 HydrophobicContact CE1-CE2 3.97Å; F401-F405 HydrophobicContact CE1-CZ 4.17Å; F401-F405 HydrophobicContact CE2-CD2 4.1Å; F401-F405 AromaticContact CE2-CE2 3.3Å; F401-F405 HydrophobicContact CE2-CE2 3.3Å; F401-F405 AromaticContact CE2-CZ 3.77Å; F401-F405 HydrophobicContact CE2-CZ 3.77Å; F401-F405 AromaticContact CZ-CD2 3.98Å; F401-F405 HydrophobicContact CZ-CD2 3.98Å; F401-F405 HydrophobicContact CZ-CE1 4.13Å; F401-F405 AromaticContact CZ-CE2 3.28Å; F401-F405 HydrophobicContact CZ-CE2 3.28Å; F401-F405 AromaticContact CZ-CZ 3.37Å; F401-F405 HydrophobicContact CZ-CZ 3.37Å; F401-F405 VanDerWaalsContact O-CD2 3.28Å; F401-F405 WeakPolarHBondContact O-CD2 3.41Å; F401-F405 PolarHBondContact O-N 3.46Å
402	H	89.5	Confident	84	Confident	0 Å²	0	32 Å²	32	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-66.1	-31.9	176.8	-71.7	-54.8	0	0	0	112.9	Y43 F101 M105 Q122 Y398 S399 F405 F406	Y43-H402 AromaticContact CD2-CE1 3.99Å; Y43-H402 AromaticContact CE1-CE1 3.9Å; Y43-H402 AromaticContact CE2-CE1 3.62Å; Y43-H402 AromaticContact CZ-CE1 3.56Å; F101-H402 AromaticContact CD1-ND1 3.98Å; M105-H402 HydrophobicContact CB-CB 3.88Å; Q122-H402 PolarHBondContact NE2-NE2 3.46Å; Q122-H402 PolarHBondContact OE1-NE2 3.09Å; Y398-H402 PolarHBondContact O-CD2 2.97Å; Y398-H402 PolarHBondContact O-N 3.34Å; S399-H402 PolarHBondContact O-N 3.31Å; H402-F405 PolarHBondContact O-N 2.92Å; H402-F406 WeakPolarHBondContact O-CB 3.02Å; H402-F406 PolarHBondContact O-N 3.23Å
403	F	89.8	Confident	85.4	Confident	67 Å²	67	22.8 Å²	22.8	29%	0.294	12%	0.121	S	C	.	.	H	α-helix	trans	-62.5	-42.9	173.2	179.2	-112.8	0	0	0	112.3	M105 S399 F400 F401 F405 F406 L407	M105-F403 HydrophobicContact CG-CB 4.23Å; M105-F403 HydrophobicContact SD-CB 3.79Å; M105-F403 HydrophobicContact SD-CD2 3.62Å; M105-F403 HydrophobicContact SD-CG 4.13Å; S399-F403 WeakPolarHBondContact O-CB 3.23Å; S399-F403 PolarHBondContact O-N 3.41Å; F400-F403 HydrophobicContact CD2-CD1 4.2Å; F400-F403 HydrophobicContact CE2-CD1 4.23Å; F400-F403 WeakPolarHBondContact O-CB 3.38Å; F400-F403 PolarHBondContact O-N 3.28Å; F401-F403 VanDerWaalsContact C-N 3.29Å; F401-F403 PolarHBondContact O-N 3.5Å; F403-F405 VanDerWaalsContact C-N 3.28Å; F403-F405 PolarHBondContact O-N 2.99Å; F403-F406 HydrophobicContact CD2-CD1 4.22Å; F403-F406 HydrophobicContact CE2-CD1 4.35Å; F403-F406 WeakPolarHBondContact O-CB 3.34Å; F403-F406 PolarHBondContact O-N 2.89Å; F403-L407 HydrophobicContact CD1-CD1 4.01Å; F403-L407 HydrophobicContact CE1-CD1 3.47Å; F403-L407 VanDerWaalsContact CE1-CD1 3.47Å; F403-L407 HydrophobicContact CE1-CG 4.3Å; F403-L407 HydrophobicContact CE2-CD1 4.18Å; F403-L407 HydrophobicContact CE2-CD2 4.35Å; F403-L407 HydrophobicContact CE2-CG 4.17Å; F403-L407 HydrophobicContact CZ-CD1 3.58Å; F403-L407 HydrophobicContact CZ-CD2 4.28Å; F403-L407 HydrophobicContact CZ-CG 4.06Å; F403-L407 WeakPolarHBondContact O-CG 3.49Å; F403-L407 PolarHBondContact O-N 2.53Å
404	I	88.6	Confident	86.4	Confident	20 Å²	20	21.3 Å²	21.3	10%	0.103	11%	0.106	C	C	.	.	H	α-helix	trans	-59.1	-42.2	174	-66.7	168.2	0	0	0	110.5	F179 L182 F400 F401 L407 A408	F179-I404 HydrophobicContact CE2-CG2 4.21Å; L182-I404 HydrophobicContact CD1-CG1 4.42Å; F400-I404 HydrophobicContact CD1-CD1 3.96Å; F400-I404 HydrophobicContact CE1-CD1 3.63Å; F400-I404 HydrophobicContact CE1-CG1 4.24Å; F400-I404 HydrophobicContact CZ-CD1 4.13Å; F400-I404 HydrophobicContact CZ-CG1 4.3Å; F400-I404 WeakPolarHBondContact O-CG1 3.38Å; F400-I404 PolarHBondContact O-N 3.04Å; F401-I404 PolarHBondContact O-N 3.03Å; I404-L407 PolarHBondContact O-N 3.21Å; I404-A408 VanDerWaalsContact O-CB 3.3Å; I404-A408 WeakPolarHBondContact O-CB 3.4Å; I404-A408 PolarHBondContact O-N 3.16Å
405	F	91.6	Very high	87.3	Confident	1 Å²	1	19.8 Å²	19.8	0%	0.004	10%	0.097	C	C	.	.	H	α-helix	trans	-71	-35.8	-179	-83.3	-120.6	0	0	0	112.9	S44 L47 F101 V345 F401 H402 F403 A408 S409	S44-F405 WeakPolarHBondContact OG-CZ 3.47Å; L47-F405 HydrophobicContact CB-CD1 4.23Å; L47-F405 HydrophobicContact CB-CE1 4.37Å; L47-F405 HydrophobicContact CD2-CD1 3.72Å; L47-F405 HydrophobicContact CD2-CE1 4.04Å; L47-F405 HydrophobicContact CD2-CG 4.33Å; F101-F405 HydrophobicContact CB-CB 4.38Å; F101-F405 HydrophobicContact CD1-CB 3.57Å; F101-F405 HydrophobicContact CD1-CD1 4.25Å; F101-F405 HydrophobicContact CD1-CG 4.3Å; F101-F405 HydrophobicContact CD2-CB 4.18Å; F101-F405 HydrophobicContact CE1-CB 3.77Å; F101-F405 AromaticContact CE1-CD1 3.55Å; F101-F405 HydrophobicContact CE1-CD1 3.55Å; F101-F405 HydrophobicContact CE1-CG 4.04Å; F101-F405 HydrophobicContact CE2-CB 4.37Å; F101-F405 HydrophobicContact CE2-CD1 4.4Å; F101-F405 HydrophobicContact CG-CB 3.79Å; F101-F405 HydrophobicContact CZ-CB 4.16Å; F101-F405 AromaticContact CZ-CD1 3.63Å; F101-F405 HydrophobicContact CZ-CD1 3.63Å; F101-F405 HydrophobicContact CZ-CG 4.39Å; V345-F405 HydrophobicContact CG1-CZ 4.28Å; F401-F405 HydrophobicContact CD2-CD2 4.43Å; F401-F405 AromaticContact CD2-CE2 3.99Å; F401-F405 HydrophobicContact CD2-CE2 3.99Å; F401-F405 HydrophobicContact CE1-CD2 4.22Å; F401-F405 AromaticContact CE1-CE2 3.97Å; F401-F405 HydrophobicContact CE1-CE2 3.97Å; F401-F405 HydrophobicContact CE1-CZ 4.17Å; F401-F405 HydrophobicContact CE2-CD2 4.1Å; F401-F405 AromaticContact CE2-CE2 3.3Å; F401-F405 HydrophobicContact CE2-CE2 3.3Å; F401-F405 AromaticContact CE2-CZ 3.77Å; F401-F405 HydrophobicContact CE2-CZ 3.77Å; F401-F405 AromaticContact CZ-CD2 3.98Å; F401-F405 HydrophobicContact CZ-CD2 3.98Å; F401-F405 HydrophobicContact CZ-CE1 4.13Å; F401-F405 AromaticContact CZ-CE2 3.28Å; F401-F405 HydrophobicContact CZ-CE2 3.28Å; F401-F405 AromaticContact CZ-CZ 3.37Å; F401-F405 HydrophobicContact CZ-CZ 3.37Å; F401-F405 VanDerWaalsContact O-CD2 3.28Å; F401-F405 WeakPolarHBondContact O-CD2 3.41Å; F401-F405 PolarHBondContact O-N 3.46Å; H402-F405 PolarHBondContact O-N 2.92Å; F403-F405 VanDerWaalsContact C-N 3.28Å; F403-F405 PolarHBondContact O-N 2.99Å; F405-A408 WeakPolarHBondContact O-CB 3.37Å; F405-A408 PolarHBondContact O-N 3.09Å; F405-S409 PolarHBondContact O-N 3.44Å
406	F	93.9	Very high	88.3	Confident	28 Å²	28	18 Å²	18	12%	0.123	9%	0.086	C	C	.	.	H	α-helix	trans	-57.8	-52.1	169	164.5	-107.9	0	0	0	110.8	A98 F101 F102 H402 F403 A408 S409 L410	A98-F406 HydrophobicContact CB-CD2 3.87Å; A98-F406 HydrophobicContact CB-CE2 3.88Å; A98-F406 WeakPolarHBondContact O-CD2 3.37Å; F101-F406 HydrophobicContact CB-CB 4.04Å; F102-F406 HydrophobicContact CB-CD2 3.85Å; F102-F406 HydrophobicContact CB-CE2 4.11Å; F102-F406 HydrophobicContact CB-CG 4.43Å; F102-F406 HydrophobicContact CD2-CD1 4.4Å; F102-F406 HydrophobicContact CD2-CD2 4.24Å; F102-F406 HydrophobicContact CD2-CE1 4.29Å; F102-F406 HydrophobicContact CD2-CE2 4.1Å; F102-F406 HydrophobicContact CD2-CG 4.37Å; F102-F406 HydrophobicContact CD2-CZ 4.12Å; F102-F406 HydrophobicContact CG-CD2 4.48Å; F102-F406 HydrophobicContact CG-CE2 4.39Å; H402-F406 WeakPolarHBondContact O-CB 3.02Å; H402-F406 PolarHBondContact O-N 3.23Å; F403-F406 HydrophobicContact CD2-CD1 4.22Å; F403-F406 HydrophobicContact CE2-CD1 4.35Å; F403-F406 WeakPolarHBondContact O-CB 3.34Å; F403-F406 PolarHBondContact O-N 2.89Å; F406-A408 VanDerWaalsContact C-N 3.32Å; F406-A408 PolarHBondContact O-N 3.29Å; F406-S409 PolarHBondContact O-N 3.34Å; F406-S409 PolarHBondContact O-OG 3.24Å; F406-L410 HydrophobicContact CE1-CD1 3.91Å; F406-L410 HydrophobicContact CE2-CD1 4.11Å; F406-L410 HydrophobicContact CE2-CG 4.44Å; F406-L410 HydrophobicContact CZ-CD1 3.66Å; F406-L410 HydrophobicContact CZ-CG 4.46Å; F406-L410 PolarHBondContact O-N 3.34Å
407	L	92.9	Very high	88.8	Confident	3 Å²	3	17 Å²	17	2%	0.016	8%	0.082	C	C	.	.	H	α-helix	trans	-62.3	-38.8	177	-68.1	178	0	0	0	112.4	I178 F179 L182 F403 I404 S409 L410 Y411	I178-L407 HydrophobicContact CB-CD1 4.27Å; I178-L407 HydrophobicContact CB-CD2 4.33Å; I178-L407 HydrophobicContact CG2-CD1 3.57Å; I178-L407 HydrophobicContact CG2-CD2 4.4Å; F179-L407 HydrophobicContact CB-CB 4.07Å; F179-L407 HydrophobicContact CD2-CB 3.84Å; F179-L407 HydrophobicContact CG-CB 4.42Å; L182-L407 HydrophobicContact CD1-CD1 3.55Å; F403-L407 HydrophobicContact CD1-CD1 4.01Å; F403-L407 HydrophobicContact CE1-CD1 3.47Å; F403-L407 VanDerWaalsContact CE1-CD1 3.47Å; F403-L407 HydrophobicContact CE1-CG 4.3Å; F403-L407 HydrophobicContact CE2-CD1 4.18Å; F403-L407 HydrophobicContact CE2-CD2 4.35Å; F403-L407 HydrophobicContact CE2-CG 4.17Å; F403-L407 HydrophobicContact CZ-CD1 3.58Å; F403-L407 HydrophobicContact CZ-CD2 4.28Å; F403-L407 HydrophobicContact CZ-CG 4.06Å; F403-L407 WeakPolarHBondContact O-CG 3.49Å; F403-L407 PolarHBondContact O-N 2.53Å; I404-L407 PolarHBondContact O-N 3.21Å; L407-S409 VanDerWaalsContact C-N 3.3Å; L407-S409 PolarHBondContact O-N 3.21Å; L407-L410 PolarHBondContact O-N 3.37Å; L407-Y411 PolarHBondContact O-N 3.42Å
408	A	93.2	Very high	88.7	Confident	1 Å²	1	12.7 Å²	12.7	1%	0.008	6%	0.059	C	C	.	.	H	α-helix	trans	-58	-43.5	175.5	0	0	0	0	0	111.1	L47 F179 W341 I404 F405 F406 L410 Y411 V412	L47-A408 HydrophobicContact CD2-CB 3.9Å; F179-A408 VanDerWaalsContact CD2-CA 3.46Å; F179-A408 HydrophobicContact CD2-CB 3.96Å; F179-A408 VanDerWaalsContact CD2-N 3.29Å; F179-A408 VanDerWaalsContact CE2-CA 3.44Å; F179-A408 HydrophobicContact CE2-CB 3.39Å; F179-A408 HydrophobicContact CZ-CB 3.8Å; W341-A408 PolarHBondContact NE1-O 2.86Å; I404-A408 VanDerWaalsContact O-CB 3.3Å; I404-A408 WeakPolarHBondContact O-CB 3.4Å; I404-A408 PolarHBondContact O-N 3.16Å; F405-A408 WeakPolarHBondContact O-CB 3.37Å; F405-A408 PolarHBondContact O-N 3.09Å; F406-A408 VanDerWaalsContact C-N 3.32Å; F406-A408 PolarHBondContact O-N 3.29Å; A408-L410 VanDerWaalsContact C-N 3.34Å; A408-L410 PolarHBondContact O-N 3.09Å; A408-Y411 WeakPolarHBondContact O-CB 3.36Å; A408-Y411 PolarHBondContact O-N 3.28Å; A408-V412 WeakPolarHBondContact O-CG2 3.34Å; A408-V412 PolarHBondContact O-N 2.7Å
409	S	94.5	Very high	88.5	Confident	0 Å²	0	13 Å²	13	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-65.4	-34.6	178	72.8	0	0	0	0	113.2	A98 F405 F406 L407 V412 M413	A98-S409 VanDerWaalsContact CA-OG 3.23Å; A98-S409 WeakPolarHBondContact CA-OG 3.43Å; A98-S409 VanDerWaalsContact CB-OG 3.31Å; A98-S409 WeakPolarHBondContact CB-OG 3.33Å; A98-S409 PolarHBondContact N-OG 3.32Å; F405-S409 PolarHBondContact O-N 3.44Å; F406-S409 PolarHBondContact O-N 3.34Å; F406-S409 PolarHBondContact O-OG 3.24Å; L407-S409 VanDerWaalsContact C-N 3.3Å; L407-S409 PolarHBondContact O-N 3.21Å; S409-V412 PolarHBondContact O-N 2.9Å; S409-M413 PolarHBondContact O-N 2.67Å; S409-M413 VanDerWaalsContact O-N 3.1Å
410	L	94.1	Very high	87.6	Confident	2 Å²	2	13.7 Å²	13.7	1%	0.01	6%	0.061	C	C	.	.	H	α-helix	trans	-69.4	-38.4	173.3	-64.6	179.2	0	0	0	111.8	A98 W168 I171 F406 L407 A408 M413 M414	A98-L410 HydrophobicContact CB-CD2 4.09Å; W168-L410 HydrophobicContact CH2-CD2 3.73Å; W168-L410 HydrophobicContact CZ2-CD2 3.48Å; W168-L410 VanDerWaalsContact CZ2-CD2 3.48Å; I171-L410 HydrophobicContact CG2-CD1 4.27Å; F406-L410 HydrophobicContact CE1-CD1 3.91Å; F406-L410 HydrophobicContact CE2-CD1 4.11Å; F406-L410 HydrophobicContact CE2-CG 4.44Å; F406-L410 HydrophobicContact CZ-CD1 3.66Å; F406-L410 HydrophobicContact CZ-CG 4.46Å; F406-L410 PolarHBondContact O-N 3.34Å; L407-L410 PolarHBondContact O-N 3.37Å; A408-L410 VanDerWaalsContact C-N 3.34Å; A408-L410 PolarHBondContact O-N 3.09Å; L410-M413 HydrophobicContact CD2-CE 4.25Å; L410-M413 WeakPolarHBondContact O-CB 3.31Å; L410-M413 PolarHBondContact O-N 2.93Å; L410-M414 WeakPolarHBondContact O-CG 3.05Å; L410-M414 PolarHBondContact O-N 3.39Å; L410-M414 VanDerWaalsContact O-N 3.09Å
411	Y	92.9	Very high	86.8	Confident	17 Å²	17	12.6 Å²	12.6	7%	0.067	5%	0.054	C	C	.	.	H	α-helix	trans	-63.2	-42.9	173.1	175.1	-92	0	0	0	112.4	A176 F179 I180 G337 M338 W341 L407 A408 M413 M414 S415	A176-Y411 HydrophobicContact CB-CD2 4.31Å; F179-Y411 HydrophobicContact CD1-CD1 4.01Å; F179-Y411 AromaticContact CD1-CD2 3.94Å; F179-Y411 HydrophobicContact CD1-CD2 3.94Å; F179-Y411 AromaticContact CD1-CG 3.53Å; F179-Y411 HydrophobicContact CD1-CG 3.53Å; F179-Y411 HydrophobicContact CE1-CD1 4.17Å; F179-Y411 HydrophobicContact CE1-CG 4.16Å; F179-Y411 HydrophobicContact CG-CG 4.33Å; I180-Y411 HydrophobicContact CD1-CD2 4.34Å; I180-Y411 HydrophobicContact CD1-CE2 4.08Å; I180-Y411 HydrophobicContact CG1-CD2 3.82Å; I180-Y411 HydrophobicContact CG1-CE2 3.6Å; G337-Y411 PolarHBondContact O-OH 3.16Å; M338-Y411 HydrophobicContact SD-CE1 4.43Å; W341-Y411 HydrophobicContact CB-CD1 4.2Å; W341-Y411 HydrophobicContact CB-CE1 3.73Å; W341-Y411 AromaticContact CD1-CD1 3.43Å; W341-Y411 VanDerWaalsContact CD1-CD1 3.43Å; W341-Y411 AromaticContact CD1-CE1 3.88Å; W341-Y411 HydrophobicContact CG-CD1 4.02Å; W341-Y411 HydrophobicContact CG-CE1 4.06Å; L407-Y411 PolarHBondContact O-N 3.42Å; A408-Y411 WeakPolarHBondContact O-CB 3.36Å; A408-Y411 PolarHBondContact O-N 3.28Å; Y411-M413 VanDerWaalsContact C-N 3.3Å; Y411-M413 PolarHBondContact O-N 3.39Å; Y411-M414 PolarHBondContact O-N 2.98Å; Y411-S415 WeakPolarHBondContact CE1-OG 3.49Å; Y411-S415 VanDerWaalsContact O-CB 3.31Å; Y411-S415 WeakPolarHBondContact O-CB 3.42Å; Y411-S415 PolarHBondContact O-N 3.32Å; Y411-S415 PolarHBondContact O-OG 3.36Å
412	V	93.2	Very high	85.8	Confident	0 Å²	0	13.4 Å²	13.4	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-57.2	-46	174.5	170.5	0	0	0	0	110.6	T51 M338 W341 A408 S409 M414 S415 L416	T51-V412 HydrophobicContact CG2-CG1 3.74Å; T51-V412 HydrophobicContact CG2-CG2 4.33Å; M338-V412 HydrophobicContact CE-CB 4.23Å; M338-V412 HydrophobicContact CE-CG1 3.9Å; M338-V412 HydrophobicContact CE-CG2 3.7Å; M338-V412 HydrophobicContact SD-CB 4.43Å; M338-V412 HydrophobicContact SD-CG1 4.42Å; M338-V412 HydrophobicContact SD-CG2 4.18Å; W341-V412 HydrophobicContact CD2-CG2 3.97Å; W341-V412 HydrophobicContact CE3-CG2 4.44Å; W341-V412 HydrophobicContact CH2-CG2 3.93Å; W341-V412 HydrophobicContact CZ2-CG2 3.34Å; W341-V412 HydrophobicContact CZ3-CG2 4.43Å; A408-V412 WeakPolarHBondContact O-CG2 3.34Å; A408-V412 PolarHBondContact O-N 2.7Å; S409-V412 PolarHBondContact O-N 2.9Å; V412-M414 PolarHBondContact O-N 3.48Å; V412-S415 PolarHBondContact O-N 3.11Å; V412-L416 HydrophobicContact CG1-CD1 3.63Å; V412-L416 HydrophobicContact CG1-CG 4.09Å; V412-L416 WeakPolarHBondContact O-CB 3.41Å; V412-L416 VanDerWaalsContact O-CG 3.31Å; V412-L416 WeakPolarHBondContact O-CG 3.32Å; V412-L416 PolarHBondContact O-N 3.29Å
413	M	91.5	Very high	84.3	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-56.7	-51.4	177.8	-173.2	-179.8	73.3	0	0	112.4	Y91 C94 W168 S409 L410 Y411 S415 T417	Y91-M413 HydrophobicContact CD1-CE 4.06Å; Y91-M413 HydrophobicContact CD1-CG 3.83Å; Y91-M413 HydrophobicContact CD1-SD 3.38Å; Y91-M413 WeakPolarHBondContact CD1-SD 3.48Å; Y91-M413 HydrophobicContact CE1-CE 3.84Å; Y91-M413 HydrophobicContact CE1-CG 4.02Å; Y91-M413 HydrophobicContact CE1-SD 3.76Å; Y91-M413 HydrophobicContact CG-CG 4.42Å; Y91-M413 HydrophobicContact CG-SD 4.32Å; C94-M413 HydrophobicContact CB-CB 3.58Å; C94-M413 HydrophobicContact CB-CG 3.79Å; C94-M413 HydrophobicContact CB-SD 4.04Å; W168-M413 VanDerWaalsContact CD1-SD 3.55Å; W168-M413 HydrophobicContact CG-SD 4.48Å; W168-M413 PolarHBondContact NE1-SD 2.8Å; S409-M413 PolarHBondContact O-N 2.67Å; S409-M413 VanDerWaalsContact O-N 3.1Å; L410-M413 HydrophobicContact CD2-CE 4.25Å; L410-M413 WeakPolarHBondContact O-CB 3.31Å; L410-M413 PolarHBondContact O-N 2.93Å; Y411-M413 VanDerWaalsContact C-N 3.3Å; Y411-M413 PolarHBondContact O-N 3.39Å; M413-S415 VanDerWaalsContact C-N 3.34Å; M413-S415 PolarHBondContact O-N 3.15Å; M413-T417 WeakPolarHBondContact O-CB 3.13Å; M413-T417 VanDerWaalsContact O-CG2 3.31Å; M413-T417 WeakPolarHBondContact O-CG2 3.32Å; M413-T417 PolarHBondContact O-N 3.34Å; M413-T417 PolarHBondContact O-OG1 2.9Å
414	M	87.8	Confident	82.7	Confident	0 Å²	0	18 Å²	18	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-67.6	-36	-178.1	-66.9	-45.1	-55.8	0	0	112.4	L169 G172 M173 A176 L410 Y411 V412 T417 N418 W419	L169-M414 HydrophobicContact CD1-CE 3.54Å; L169-M414 HydrophobicContact CD1-SD 4.14Å; G172-M414 VanDerWaalsContact C-CG 3.44Å; G172-M414 WeakPolarHBondContact O-CG 3.43Å; M173-M414 HydrophobicContact CG-CE 3.77Å; M173-M414 HydrophobicContact CG-SD 4.42Å; A176-M414 HydrophobicContact CB-CB 3.94Å; A176-M414 HydrophobicContact CB-CG 3.75Å; L410-M414 WeakPolarHBondContact O-CG 3.05Å; L410-M414 PolarHBondContact O-N 3.39Å; L410-M414 VanDerWaalsContact O-N 3.09Å; Y411-M414 PolarHBondContact O-N 2.98Å; V412-M414 PolarHBondContact O-N 3.48Å; M414-T417 PolarHBondContact O-OG1 3.31Å; M414-N418 PolarHBondContact O-N 3.26Å; M414-W419 HydrophobicContact CB-CD2 4.14Å; M414-W419 HydrophobicContact CB-CH2 4.45Å; M414-W419 HydrophobicContact CB-CZ2 4.04Å; M414-W419 HydrophobicContact CE-CB 4.29Å; M414-W419 HydrophobicContact CE-CD2 4.06Å; M414-W419 HydrophobicContact CE-CE3 3.86Å; M414-W419 HydrophobicContact CE-CG 4.28Å; M414-W419 PolarHBondContact O-N 2.94Å
415	S	88.2	Confident	80.7	Confident	4 Å²	4	20.6 Å²	20.6	3%	0.028	11%	0.109	C	C	.	.	H	α-helix	trans	-70.4	-45.3	178.6	-57.5	0	0	0	0	111.7	S334 Y411 V412 M413 T417 N418	S334-S415 WeakPolarHBondContact CB-O 3.29Å; S334-S415 PolarHBondContact OG-O 2.84Å; Y411-S415 WeakPolarHBondContact CE1-OG 3.49Å; Y411-S415 VanDerWaalsContact O-CB 3.31Å; Y411-S415 WeakPolarHBondContact O-CB 3.42Å; Y411-S415 PolarHBondContact O-N 3.32Å; Y411-S415 PolarHBondContact O-OG 3.36Å; V412-S415 PolarHBondContact O-N 3.11Å; M413-S415 VanDerWaalsContact C-N 3.34Å; M413-S415 PolarHBondContact O-N 3.15Å; S415-T417 PolarHBondContact O-N 3.33Å; S415-N418 PolarHBondContact O-N 3.35Å
416	L	87.5	Confident	78.5	Confident	3 Å²	3	25.3 Å²	25.3	2%	0.016	14%	0.135	C	C	.	.	H	α-helix	trans	-70	-19.5	179.3	-70.9	-175.8	0	0	0	113.7	L58 V90 V330 M338 V412	L58-L416 HydrophobicContact CD1-CB 4Å; L58-L416 HydrophobicContact CD1-CD1 4.46Å; L58-L416 HydrophobicContact CD1-CD2 4.22Å; L58-L416 HydrophobicContact CD1-CG 4.46Å; V90-L416 HydrophobicContact CG1-CB 3.86Å; V90-L416 HydrophobicContact CG1-CD1 4.19Å; V330-L416 HydrophobicContact CG2-CD2 4.23Å; M338-L416 HydrophobicContact CG-CD2 4.25Å; V412-L416 HydrophobicContact CG1-CD1 3.63Å; V412-L416 HydrophobicContact CG1-CG 4.09Å; V412-L416 WeakPolarHBondContact O-CB 3.41Å; V412-L416 VanDerWaalsContact O-CG 3.31Å; V412-L416 WeakPolarHBondContact O-CG 3.32Å; V412-L416 PolarHBondContact O-N 3.29Å
417	T	81.7	Confident	76.4	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.137	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.5	11.2	177.8	58.4	0	0	0	0	113	Y87 V90 Y91 M413 M414 S415 W419 Y420	Y87-T417 HydrophobicContact CD1-CG2 4.04Å; Y87-T417 HydrophobicContact CG-CG2 4.23Å; V90-T417 HydrophobicContact CB-CG2 4.11Å; V90-T417 HydrophobicContact CG1-CG2 3.9Å; Y91-T417 HydrophobicContact CD2-CG2 4.02Å; Y91-T417 HydrophobicContact CE2-CG2 3.68Å; M413-T417 WeakPolarHBondContact O-CB 3.13Å; M413-T417 VanDerWaalsContact O-CG2 3.31Å; M413-T417 WeakPolarHBondContact O-CG2 3.32Å; M413-T417 PolarHBondContact O-N 3.34Å; M413-T417 PolarHBondContact O-OG1 2.9Å; M414-T417 PolarHBondContact O-OG1 3.31Å; S415-T417 PolarHBondContact O-N 3.33Å; T417-W419 PolarHBondContact O-N 3Å; T417-Y420 WeakPolarHBondContact O-CB 3.2Å; T417-Y420 PolarHBondContact O-N 3.48Å
418	N	76.9	Confident	74.2	Confident	5 Å²	5	33.8 Å²	33.8	3%	0.027	17%	0.173	C	C	.	.	T	Hydrogen-bonded Turn	trans	47.9	32.2	-178	-55.7	-36.2	0	0	0	114.5	Y87 G329 S331 S334 M414 S415 Y420 N431	Y87-N418 PolarHBondContact OH-ND2 3.16Å; G329-N418 PolarHBondContact O-ND2 3.48Å; S331-N418 PolarHBondContact N-OD1 3.3Å; S331-N418 VanDerWaalsContact N-OD1 3.15Å; S331-N418 PolarHBondContact OG-OD1 2.85Å; S334-N418 PolarHBondContact OG-OD1 2.84Å; M414-N418 PolarHBondContact O-N 3.26Å; S415-N418 PolarHBondContact O-N 3.35Å; N418-Y420 PolarHBondContact O-N 3.21Å; N418-N431 WeakPolarHBondContact CB-OD1 3.03Å
419	W	76	Confident	72.2	Confident	8 Å²	8	40.6 Å²	40.6	3%	0.03	20%	0.198	C	C	.	.	T	Hydrogen-bonded Turn	trans	58.4	26	-177.2	-60.4	71.5	0	0	0	114.9	M173 A176 I180 M414 T417 S436 V439	M173-W419 HydrophobicContact CB-CZ3 4.1Å; M173-W419 HydrophobicContact CG-CE3 3.99Å; M173-W419 HydrophobicContact CG-CZ3 3.91Å; A176-W419 HydrophobicContact CB-CH2 3.5Å; A176-W419 HydrophobicContact CB-CZ2 3.79Å; A176-W419 HydrophobicContact CB-CZ3 4.41Å; I180-W419 HydrophobicContact CD1-CH2 4.38Å; I180-W419 HydrophobicContact CD1-CZ2 4.08Å; M414-W419 HydrophobicContact CB-CD2 4.14Å; M414-W419 HydrophobicContact CB-CH2 4.45Å; M414-W419 HydrophobicContact CB-CZ2 4.04Å; M414-W419 HydrophobicContact CE-CB 4.29Å; M414-W419 HydrophobicContact CE-CD2 4.06Å; M414-W419 HydrophobicContact CE-CE3 3.86Å; M414-W419 HydrophobicContact CE-CG 4.28Å; M414-W419 PolarHBondContact O-N 2.94Å; T417-W419 PolarHBondContact O-N 3Å; W419-S436 VanDerWaalsContact CG-OG 3.26Å; W419-V439 HydrophobicContact CH2-CG1 3.78Å; W419-V439 HydrophobicContact CZ2-CG1 4.48Å; W419-V439 HydrophobicContact CZ3-CG1 4.17Å
420	Y	67.5	Low	70.2	Confident	29 Å²	29	42.3 Å²	42.3	11%	0.114	21%	0.207	C	C	.	.			trans	-62.8	137.8	-179.7	173.5	-109.5	0	0	0	112.9	Y87 L169 T417 N418 P422 E424 L430	Y87-Y420 AromaticContact CD2-CD1 3.84Å; Y87-Y420 HydrophobicContact CD2-CD1 3.84Å; Y87-Y420 HydrophobicContact CD2-CG 4.15Å; Y87-Y420 HydrophobicContact CE2-CD1 4.27Å; Y87-Y420 HydrophobicContact CE2-CG 4.12Å; L169-Y420 WeakPolarHBondContact CD1-O 3.45Å; T417-Y420 WeakPolarHBondContact O-CB 3.2Å; T417-Y420 PolarHBondContact O-N 3.48Å; N418-Y420 PolarHBondContact O-N 3.21Å; Y420-P422 HydrophobicContact CE1-CB 4.49Å; Y420-E424 PolarHBondContact OH-O 3.49Å; Y420-L430 HydrophobicContact CD2-CD2 3.9Å; Y420-L430 HydrophobicContact CE2-CD2 3.82Å; Y420-L430 HydrophobicContact CG-CD2 4.43Å
421	R	67.2	Low	68.3	Low	71 Å²	71	44.3 Å²	44.3	27%	0.268	22%	0.218	S	C	.	.			trans	-94.5	122	172.4	-84.1	-177.2	155.1	179.7	-7.4	110.7	L169 D423 N433	L169-R421 HydrophobicContact CD2-CG 3.92Å; R421-D423 PolarHBondContact O-N 3.39Å; R421-N433 WeakPolarHBondContact CD-ND2 3.36Å; R421-N433 PolarHBondContact NE-ND2 3.02Å
422	P	62.3	Low	66.6	Low	23 Å²	23	44.4 Å²	44.4	15%	0.149	22%	0.221	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.1	-12.8	-177.8	30.1	-33.2	0	0	0	114.2	I166 Y420	I166-P422 HydrophobicContact CG1-CG 4.13Å; Y420-P422 HydrophobicContact CE1-CB 4.49Å
423	D	59.2	Low	65.6	Low	89 Å²	89	45.5 Å²	45.5	48%	0.476	23%	0.227	S	C	.	.	T	Hydrogen-bonded Turn	trans	-87.4	-12.7	-175.6	-59	-27.5	0	0	0	113.5	I166 R421	I166-D423 WeakPolarHBondContact CD1-OD1 3.28Å; I166-D423 VanDerWaalsContact CG1-OD1 3.23Å; I166-D423 WeakPolarHBondContact CG1-OD1 3.38Å; R421-D423 PolarHBondContact O-N 3.39Å
424	E	56.5	Low	65.1	Low	75 Å²	75	48.2 Å²	48.2	35%	0.35	24%	0.241	S	C	.	.			trans	-92.9	106.5	-179.3	-68.1	177.5	-153.4	0	0	109	Y420 D426	Y420-E424 PolarHBondContact OH-O 3.49Å; E424-D426 PolarHBondContact O-N 3.39Å
425	A	45.2	Very low	64.7	Low	74 Å²	74	49.8 Å²	49.8	61%	0.612	25%	0.254	S	S	*	.			trans	-63.9	-1.5	-175.5	0	0	0	0	0	115
426	D	46.6	Very low	64.3	Low	100 Å²	100	49.7 Å²	49.7	54%	0.535	25%	0.253	S	S	.	.			trans	-100.5	97.3	178.6	-80.3	-33.7	0	0	0	111.4	E424 F428 R429	E424-D426 PolarHBondContact O-N 3.39Å; D426-F428 PolarHBondContact O-N 3Å; D426-R429 PolarHBondContact O-N 3.34Å
427	L	50.4	Low	64.2	Low	32 Å²	32	49.5 Å²	49.5	17%	0.168	25%	0.252	C	S	.	.	G	3₁₀ helix	trans	-59	-6.6	164.5	-85.5	104.4	0	0	0	113.2	R83 R429 L430	R83-L427 HydrophobicContact CB-CD2 3.41Å; R83-L427 VanDerWaalsContact CB-CD2 3.41Å; R83-L427 HydrophobicContact CG-CD2 4.35Å; L427-R429 VanDerWaalsContact C-N 3.32Å; L427-L430 HydrophobicContact CB-CD1 4.01Å; L427-L430 HydrophobicContact CB-CG 4.18Å; L427-L430 HydrophobicContact CD2-CD1 4Å; L427-L430 HydrophobicContact CD2-CD2 4.15Å; L427-L430 HydrophobicContact CD2-CG 4.47Å; L427-L430 HydrophobicContact CG-CD1 4.26Å; L427-L430 HydrophobicContact CG-CD2 4.11Å; L427-L430 HydrophobicContact CG-CG 4.31Å; L427-L430 WeakPolarHBondContact O-CD1 3.4Å; L427-L430 WeakPolarHBondContact O-CG 3.4Å
428	F	45.9	Very low	64.5	Low	177 Å²	177	55.3 Å²	55.3	78%	0.776	27%	0.274	S	S	*	.	G	3₁₀ helix	trans	-78.3	-17.1	171.5	-70	-77.3	0	0	0	113.1	D426	D426-F428 PolarHBondContact O-N 3Å
429	R	51.3	Low	64.9	Low	143 Å²	143	56.5 Å²	56.5	54%	0.54	28%	0.281	S	S	.	.	G	3₁₀ helix	trans	-109.1	29.6	176.4	-70.6	-171.4	168.1	-178.4	-2.8	113.1	D426 L427 N431 S432	D426-R429 PolarHBondContact O-N 3.34Å; L427-R429 VanDerWaalsContact C-N 3.32Å; R429-N431 PolarHBondContact O-N 2.91Å; R429-S432 PolarHBondContact O-N 3.45Å
430	L	52.5	Low	65.4	Low	36 Å²	36	56.6 Å²	56.6	19%	0.188	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55	-15.5	-175.1	-81.4	158.4	0	0	0	116.2	Y87 Y420 L427	Y87-L430 HydrophobicContact CE2-CD2 3.91Å; Y420-L430 HydrophobicContact CD2-CD2 3.9Å; Y420-L430 HydrophobicContact CE2-CD2 3.82Å; Y420-L430 HydrophobicContact CG-CD2 4.43Å; L427-L430 HydrophobicContact CB-CD1 4.01Å; L427-L430 HydrophobicContact CB-CG 4.18Å; L427-L430 HydrophobicContact CD2-CD1 4Å; L427-L430 HydrophobicContact CD2-CD2 4.15Å; L427-L430 HydrophobicContact CD2-CG 4.47Å; L427-L430 HydrophobicContact CG-CD1 4.26Å; L427-L430 HydrophobicContact CG-CD2 4.11Å; L427-L430 HydrophobicContact CG-CG 4.31Å; L427-L430 WeakPolarHBondContact O-CD1 3.4Å; L427-L430 WeakPolarHBondContact O-CG 3.4Å
431	N	54.7	Low	66.6	Low	44 Å²	44	55.2 Å²	55.2	24%	0.235	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	-117.2	-1.5	-168.7	-151.7	53.6	0	0	0	115.1	S296 E333 N418 R429	S296-N431 PolarHBondContact O-ND2 3.12Å; E333-N431 PolarHBondContact OE1-ND2 3.45Å; N418-N431 WeakPolarHBondContact CB-OD1 3.03Å; R429-N431 PolarHBondContact O-N 2.91Å
432	S	57.4	Low	67.7	Low	19 Å²	19	53.4 Å²	53.4	13%	0.133	28%	0.277	C	S	.	.			trans	-136.5	104.4	-158.8	57.5	0	0	0	0	115.5	N297 E298 P299 R429	N297-S432 CarbonylContact O-C 3.53Å; N297-S432 VanDerWaalsContact O-CA 3.22Å; N297-S432 WeakPolarHBondContact O-CA 3.19Å; N297-S432 WeakPolarHBondContact O-CB 3.31Å; E298-S432 VanDerWaalsContact O-CB 3.32Å; E298-S432 WeakPolarHBondContact O-CB 3.43Å; P299-S432 WeakPolarHBondContact CA-OG 3.39Å; R429-S432 PolarHBondContact O-N 3.45Å
433	N	71.9	Confident	68.9	Low	23 Å²	23	52.3 Å²	52.3	12%	0.123	27%	0.27	C	S	.	.			trans	-134.4	126.8	177.3	177.2	1.9	0	0	0	109.5	N297 R421 A435 S436 V437	N297-N433 PolarHBondContact O-N 3.5Å; R421-N433 WeakPolarHBondContact CD-ND2 3.36Å; R421-N433 PolarHBondContact NE-ND2 3.02Å; N433-A435 PolarHBondContact O-N 2.83Å; N433-A435 VanDerWaalsContact O-N 3.11Å; N433-A435 WeakPolarHBondContact OD1-CB 3.49Å; N433-A435 PolarHBondContact OD1-N 2.94Å; N433-S436 WeakPolarHBondContact O-CB 3.41Å; N433-S436 PolarHBondContact O-N 3.46Å; N433-V437 PolarHBondContact O-N 2.7Å
434	M	80.8	Confident	70.4	Confident	58 Å²	58	48.1 Å²	48.1	29%	0.286	25%	0.247	S	C	.	.	H	α-helix	trans	-53	-33.1	175.6	-67.4	-52.9	-69.4	0	0	113.2	L244 P299 S436 V437 W438	L244-M434 HydrophobicContact CD2-CE 3.73Å; P299-M434 WeakPolarHBondContact CD-SD 3.34Å; P299-M434 HydrophobicContact CG-CG 3.91Å; P299-M434 HydrophobicContact CG-SD 3.6Å; P299-M434 VanDerWaalsContact CG-SD 3.6Å; M434-S436 VanDerWaalsContact C-N 3.27Å; M434-S436 PolarHBondContact O-N 3.01Å; M434-V437 WeakPolarHBondContact O-CB 3.33Å; M434-V437 PolarHBondContact O-N 3.21Å; M434-V437 HydrophobicContact SD-CG2 4.49Å; M434-W438 PolarHBondContact O-N 2.78Å
435	A	79.3	Confident	72.1	Confident	33 Å²	33	48.9 Å²	48.9	27%	0.273	25%	0.247	S	C	.	.	H	α-helix	trans	-60	-39.8	177.4	0	0	0	0	0	111.7	N433 V439	N433-A435 PolarHBondContact O-N 2.83Å; N433-A435 VanDerWaalsContact O-N 3.11Å; N433-A435 WeakPolarHBondContact OD1-CB 3.49Å; N433-A435 PolarHBondContact OD1-N 2.94Å; A435-V439 WeakPolarHBondContact O-CB 3.34Å; A435-V439 WeakPolarHBondContact O-CG2 3.35Å; A435-V439 PolarHBondContact O-N 3.01Å
436	S	78.9	Confident	74.2	Confident	1 Å²	1	47.7 Å²	47.7	1%	0.007	23%	0.232	C	C	.	.	H	α-helix	trans	-67.4	-40.9	177.1	-169.2	0	0	0	0	111.5	N297 W419 N433 M434 V439 K440	N297-S436 PolarHBondContact ND2-OG 3.26Å; W419-S436 VanDerWaalsContact CG-OG 3.26Å; N433-S436 WeakPolarHBondContact O-CB 3.41Å; N433-S436 PolarHBondContact O-N 3.46Å; M434-S436 VanDerWaalsContact C-N 3.27Å; M434-S436 PolarHBondContact O-N 3.01Å; S436-V439 PolarHBondContact O-N 2.96Å; S436-K440 WeakPolarHBondContact O-CG 3.28Å; S436-K440 PolarHBondContact O-N 2.9Å; S436-K440 VanDerWaalsContact O-N 3.08Å
437	V	86.1	Confident	76.2	Confident	0 Å²	0	43 Å²	43	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-57	-53.6	175.1	-174.3	0	0	0	0	110.1	F248 A294 M295 N297 N433 M434 V439 K440 I441	F248-V437 HydrophobicContact CE2-CG1 4.22Å; A294-V437 HydrophobicContact CB-CG1 4.12Å; A294-V437 WeakPolarHBondContact O-CG2 3.48Å; M295-V437 HydrophobicContact CE-CG1 3.75Å; N297-V437 HydrophobicContact CB-CG2 4.15Å; N297-V437 WeakPolarHBondContact O-CG2 3.25Å; N433-V437 PolarHBondContact O-N 2.7Å; M434-V437 WeakPolarHBondContact O-CB 3.33Å; M434-V437 PolarHBondContact O-N 3.21Å; M434-V437 HydrophobicContact SD-CG2 4.49Å; V437-V439 PolarHBondContact O-N 2.97Å; V437-K440 PolarHBondContact O-N 3.15Å; V437-I441 HydrophobicContact CG1-CG1 4.36Å; V437-I441 WeakPolarHBondContact O-CG1 3.27Å; V437-I441 PolarHBondContact O-N 3.17Å
438	W	87.8	Confident	77.9	Confident	122 Å²	122	41.6 Å²	41.6	46%	0.462	20%	0.2	S	C	.	.	H	α-helix	trans	-63.1	-40.8	-179.5	-81	107.9	0	0	0	113.2	F248 M434 K440 I441 A442 W445	F248-W438 HydrophobicContact CE1-CH2 4.14Å; F248-W438 HydrophobicContact CE1-CZ3 4.25Å; F248-W438 AromaticContact CZ-CH2 3.95Å; F248-W438 HydrophobicContact CZ-CH2 3.95Å; F248-W438 HydrophobicContact CZ-CZ2 4.07Å; F248-W438 HydrophobicContact CZ-CZ3 4.22Å; M434-W438 PolarHBondContact O-N 2.78Å; W438-K440 VanDerWaalsContact C-N 3.31Å; W438-K440 PolarHBondContact O-N 3.32Å; W438-I441 PolarHBondContact O-N 2.9Å; W438-A442 WeakPolarHBondContact O-CB 3.3Å; W438-A442 PolarHBondContact O-N 3.28Å; W438-W445 HydrophobicContact CZ3-CH2 4.3Å
439	V	84.6	Confident	80	Confident	29 Å²	29	35.2 Å²	35.2	18%	0.176	18%	0.18	C	C	.	.	H	α-helix	trans	-58	-44.8	175.6	161.1	0	0	0	0	110.8	F177 I180 W419 A435 S436 V437 S443	F177-V439 HydrophobicContact CB-CG1 4.25Å; F177-V439 HydrophobicContact CD2-CG1 3.98Å; I180-V439 HydrophobicContact CD1-CG1 4.12Å; W419-V439 HydrophobicContact CH2-CG1 3.78Å; W419-V439 HydrophobicContact CZ2-CG1 4.48Å; W419-V439 HydrophobicContact CZ3-CG1 4.17Å; A435-V439 WeakPolarHBondContact O-CB 3.34Å; A435-V439 WeakPolarHBondContact O-CG2 3.35Å; A435-V439 PolarHBondContact O-N 3.01Å; S436-V439 PolarHBondContact O-N 2.96Å; V437-V439 PolarHBondContact O-N 2.97Å; V439-S443 VanDerWaalsContact O-CB 3.28Å; V439-S443 WeakPolarHBondContact O-CB 3.39Å; V439-S443 PolarHBondContact O-N 3.27Å; V439-S443 PolarHBondContact O-OG 3.39Å
440	K	87.9	Confident	81.6	Confident	11 Å²	11	30.8 Å²	30.8	5%	0.048	17%	0.167	C	C	.	.	H	α-helix	trans	-72.5	-40.4	-179.4	-69.6	174.3	-179.9	-176.7	0	112.7	S293 A294 N297 S436 V437 W438 S443 S444	S293-K440 WeakPolarHBondContact O-CD 3.14Å; S293-K440 PolarHBondContact O-NZ 3.22Å; S293-K440 WeakPolarHBondContact OG-CE 3.21Å; S293-K440 PolarHBondContact OG-NZ 3Å; A294-K440 HydrophobicContact CB-CB 3.76Å; A294-K440 HydrophobicContact CB-CD 4.31Å; N297-K440 PolarHBondContact ND2-NZ 3.04Å; S436-K440 WeakPolarHBondContact O-CG 3.28Å; S436-K440 PolarHBondContact O-N 2.9Å; S436-K440 VanDerWaalsContact O-N 3.08Å; V437-K440 PolarHBondContact O-N 3.15Å; W438-K440 VanDerWaalsContact C-N 3.31Å; W438-K440 PolarHBondContact O-N 3.32Å; K440-S443 WeakPolarHBondContact O-CB 3.4Å; K440-S443 PolarHBondContact O-N 3.13Å; K440-S444 PolarHBondContact O-N 3.47Å
441	I	91.7	Very high	83	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-68.7	-44.1	176.3	-66.2	-60.3	0	0	0	111.8	F248 T291 A294 M295 V437 W438 S443 S444 W445	F248-I441 HydrophobicContact CB-CD1 4.08Å; F248-I441 HydrophobicContact CD1-CG1 4.48Å; F248-I441 HydrophobicContact CD1-CG2 3.93Å; F248-I441 HydrophobicContact CD2-CD1 4.41Å; F248-I441 HydrophobicContact CD2-CG1 4.22Å; F248-I441 HydrophobicContact CE1-CG2 4Å; F248-I441 HydrophobicContact CE2-CG1 4.36Å; F248-I441 HydrophobicContact CG-CD1 4.17Å; F248-I441 HydrophobicContact CG-CG1 4.25Å; F248-I441 HydrophobicContact CG-CG2 4.48Å; T291-I441 HydrophobicContact CG2-CD1 4.49Å; A294-I441 HydrophobicContact CB-CD1 3.76Å; A294-I441 HydrophobicContact CB-CG1 3.82Å; M295-I441 HydrophobicContact CE-CD1 4.22Å; M295-I441 HydrophobicContact CE-CG1 4.48Å; V437-I441 HydrophobicContact CG1-CG1 4.36Å; V437-I441 WeakPolarHBondContact O-CG1 3.27Å; V437-I441 PolarHBondContact O-N 3.17Å; W438-I441 PolarHBondContact O-N 2.9Å; I441-S443 VanDerWaalsContact C-N 3.25Å; I441-S443 PolarHBondContact O-N 3.08Å; I441-S444 PolarHBondContact O-N 3.27Å; I441-S444 VanDerWaalsContact O-N 3.1Å; I441-S444 PolarHBondContact O-OG 2.95Å; I441-W445 HydrophobicContact CG2-CD2 4.33Å; I441-W445 HydrophobicContact CG2-CH2 4.12Å; I441-W445 HydrophobicContact CG2-CZ2 3.51Å; I441-W445 PolarHBondContact O-N 3.1Å
442	A	90.8	Very high	84.4	Confident	33 Å²	33	28.5 Å²	28.5	27%	0.273	16%	0.158	S	C	.	.	H	α-helix	trans	-60.8	-40	174.7	0	0	0	0	0	110.9	W438 S444 W445 V446	W438-A442 WeakPolarHBondContact O-CB 3.3Å; W438-A442 PolarHBondContact O-N 3.28Å; A442-S444 VanDerWaalsContact C-N 3.31Å; A442-S444 PolarHBondContact O-N 2.79Å; A442-W445 PolarHBondContact O-N 2.81Å; A442-V446 WeakPolarHBondContact O-CG2 3.31Å; A442-V446 PolarHBondContact O-N 3.46Å
443	S	88.1	Confident	85.5	Confident	0 Å²	0	33 Å²	33	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-61.4	-37.4	174.5	-62	0	0	0	0	112.4	I180 L184 V439 K440 I441 W445 V446 C447	I180-S443 VanDerWaalsContact CG2-OG 3.31Å; I180-S443 WeakPolarHBondContact CG2-OG 3.41Å; L184-S443 WeakPolarHBondContact CD1-O 3.18Å; V439-S443 VanDerWaalsContact O-CB 3.28Å; V439-S443 WeakPolarHBondContact O-CB 3.39Å; V439-S443 PolarHBondContact O-N 3.27Å; V439-S443 PolarHBondContact O-OG 3.39Å; K440-S443 WeakPolarHBondContact O-CB 3.4Å; K440-S443 PolarHBondContact O-N 3.13Å; I441-S443 VanDerWaalsContact C-N 3.25Å; I441-S443 PolarHBondContact O-N 3.08Å; S443-W445 VanDerWaalsContact C-N 3.34Å; S443-W445 PolarHBondContact O-N 3.16Å; S443-V446 PolarHBondContact O-N 3.22Å; S443-C447 WeakPolarHBondContact O-CB 3.43Å; S443-C447 PolarHBondContact O-N 3.37Å
444	S	91.2	Very high	85.7	Confident	0 Å²	0	35 Å²	35	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-66	-37.4	177.1	75.8	0	0	0	0	112.2	N252 K440 I441 A442 C447 A448	N252-S444 PolarHBondContact ND2-OG 2.95Å; N252-S444 PolarHBondContact OD1-OG 3.41Å; N252-S444 VanDerWaalsContact OD1-OG 3.06Å; K440-S444 PolarHBondContact O-N 3.47Å; I441-S444 PolarHBondContact O-N 3.27Å; I441-S444 VanDerWaalsContact O-N 3.1Å; I441-S444 PolarHBondContact O-OG 2.95Å; A442-S444 VanDerWaalsContact C-N 3.31Å; A442-S444 PolarHBondContact O-N 2.79Å; S444-C447 WeakPolarHBondContact O-CB 3.31Å; S444-C447 PolarHBondContact O-N 3.16Å; S444-A448 PolarHBondContact O-N 3.03Å; S444-A448 VanDerWaalsContact O-N 3.09Å
445	W	92.2	Very high	85.2	Confident	91 Å²	91	32.4 Å²	32.4	35%	0.345	18%	0.177	S	C	.	.	H	α-helix	trans	-69.7	-40.8	174.7	-58.2	-15.8	0	0	0	112.5	I251 N252 L255 W438 I441 A442 S443 C447 A448 A449	I251-W445 HydrophobicContact CG2-CZ2 4.44Å; N252-W445 VanDerWaalsContact OD1-CD1 3.25Å; N252-W445 PolarHBondContact OD1-NE1 3.35Å; L255-W445 VanDerWaalsContact CD1-CD1 3.45Å; L255-W445 HydrophobicContact CD1-CG 4.26Å; W438-W445 HydrophobicContact CZ3-CH2 4.3Å; I441-W445 HydrophobicContact CG2-CD2 4.33Å; I441-W445 HydrophobicContact CG2-CH2 4.12Å; I441-W445 HydrophobicContact CG2-CZ2 3.51Å; I441-W445 PolarHBondContact O-N 3.1Å; A442-W445 PolarHBondContact O-N 2.81Å; S443-W445 VanDerWaalsContact C-N 3.34Å; S443-W445 PolarHBondContact O-N 3.16Å; W445-C447 VanDerWaalsContact C-N 3.26Å; W445-C447 PolarHBondContact O-N 3.44Å; W445-A448 PolarHBondContact O-N 3.26Å; W445-A449 WeakPolarHBondContact O-CB 3.33Å; W445-A449 PolarHBondContact O-N 3.37Å
446	V	89.4	Confident	84.8	Confident	50 Å²	50	33.4 Å²	33.4	30%	0.303	18%	0.179	S	C	.	.	H	α-helix	trans	-59.7	-40.5	172.6	171.5	0	0	0	0	110.2	V181 L184 A442 S443 A449 L450	V181-V446 HydrophobicContact CG1-CG1 4.28Å; V181-V446 HydrophobicContact CG2-CG1 4.48Å; L184-V446 HydrophobicContact CD1-CB 4.36Å; L184-V446 HydrophobicContact CD1-CG1 4.23Å; A442-V446 WeakPolarHBondContact O-CG2 3.31Å; A442-V446 PolarHBondContact O-N 3.46Å; S443-V446 PolarHBondContact O-N 3.22Å; V446-A449 PolarHBondContact O-N 2.92Å; V446-L450 HydrophobicContact CG1-CD1 3.84Å; V446-L450 HydrophobicContact CG1-CG 4.13Å; V446-L450 WeakPolarHBondContact O-CB 3.46Å; V446-L450 VanDerWaalsContact O-CG 3.23Å; V446-L450 WeakPolarHBondContact O-CG 3.25Å; V446-L450 PolarHBondContact O-N 3.28Å
447	C	86.9	Confident	84.2	Confident	0 Å²	0	36.9 Å²	36.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-61.7	-47.7	176.6	-165.2	0	0	0	0	112.5	L184 I283 I287 S443 S444 W445 A449 L450 L451	L184-C447 HydrophobicContact CB-CB 4.47Å; L184-C447 HydrophobicContact CD1-CB 3.93Å; L184-C447 HydrophobicContact CD2-CB 3.63Å; L184-C447 HydrophobicContact CG-CB 4.2Å; I283-C447 VanDerWaalsContact CG2-SG 3.55Å; I287-C447 HydrophobicContact CG1-CB 4.29Å; S443-C447 WeakPolarHBondContact O-CB 3.43Å; S443-C447 PolarHBondContact O-N 3.37Å; S444-C447 WeakPolarHBondContact O-CB 3.31Å; S444-C447 PolarHBondContact O-N 3.16Å; W445-C447 VanDerWaalsContact C-N 3.26Å; W445-C447 PolarHBondContact O-N 3.44Å; C447-A449 VanDerWaalsContact C-N 3.32Å; C447-A449 PolarHBondContact O-N 3.48Å; C447-L450 PolarHBondContact O-N 2.88Å; C447-L451 PolarHBondContact O-N 3.4Å
448	A	87.8	Confident	82.9	Confident	4 Å²	4	40.9 Å²	40.9	3%	0.033	22%	0.219	C	C	.	.	H	α-helix	trans	-61.6	-42.1	176.6	0	0	0	0	0	111.6	L255 V259 I287 S444 W445 A452	L255-A448 HydrophobicContact CB-CB 4.26Å; L255-A448 HydrophobicContact CD1-CB 4.39Å; V259-A448 HydrophobicContact CG2-CB 4.28Å; I287-A448 HydrophobicContact CD1-CB 4.02Å; S444-A448 PolarHBondContact O-N 3.03Å; S444-A448 VanDerWaalsContact O-N 3.09Å; W445-A448 PolarHBondContact O-N 3.26Å; A448-A452 WeakPolarHBondContact O-CB 3.21Å; A448-A452 PolarHBondContact O-N 2.83Å
449	A	88.5	Confident	81.5	Confident	43 Å²	43	38.3 Å²	38.3	36%	0.355	21%	0.212	S	C	.	.	H	α-helix	trans	-65.3	-43.6	176.9	0	0	0	0	0	112.1	W445 V446 C447 A452 M453	W445-A449 WeakPolarHBondContact O-CB 3.33Å; W445-A449 PolarHBondContact O-N 3.37Å; V446-A449 PolarHBondContact O-N 2.92Å; C447-A449 VanDerWaalsContact C-N 3.32Å; C447-A449 PolarHBondContact O-N 3.48Å; A449-A452 PolarHBondContact O-N 3.44Å; A449-M453 VanDerWaalsContact O-CB 3.27Å; A449-M453 WeakPolarHBondContact O-CB 3.48Å; A449-M453 VanDerWaalsContact O-CG 3.23Å; A449-M453 WeakPolarHBondContact O-CG 3.47Å; A449-M453 PolarHBondContact O-N 3.49Å
450	L	84.8	Confident	80.2	Confident	50 Å²	50	43.2 Å²	43.2	26%	0.262	24%	0.235	S	C	.	.	H	α-helix	trans	-60.4	-46.3	176.9	-76.9	172.2	0	0	0	111.2	L184 I185 V446 C447 M453 D454	L184-L450 HydrophobicContact CB-CD1 4.43Å; I185-L450 HydrophobicContact CD1-CD1 4.47Å; I185-L450 HydrophobicContact CG1-CD1 3.63Å; V446-L450 HydrophobicContact CG1-CD1 3.84Å; V446-L450 HydrophobicContact CG1-CG 4.13Å; V446-L450 WeakPolarHBondContact O-CB 3.46Å; V446-L450 VanDerWaalsContact O-CG 3.23Å; V446-L450 WeakPolarHBondContact O-CG 3.25Å; V446-L450 PolarHBondContact O-N 3.28Å; C447-L450 PolarHBondContact O-N 2.88Å; L450-M453 PolarHBondContact O-N 3.31Å; L450-D454 WeakPolarHBondContact O-CB 3.47Å; L450-D454 PolarHBondContact O-N 3.23Å
451	L	83.3	Confident	78.8	Confident	2 Å²	2	48 Å²	48	1%	0.01	27%	0.27	C	S	.	.	H	α-helix	trans	-64	-44.2	177.1	-179.8	57.1	0	0	0	111.4	V188 V259 I283 C447 M453 D454 I455	V188-L451 HydrophobicContact CG1-CD1 4.35Å; V259-L451 HydrophobicContact CG1-CB 4.23Å; V259-L451 HydrophobicContact CG1-CD2 3.3Å; V259-L451 HydrophobicContact CG1-CG 3.57Å; I283-L451 HydrophobicContact CB-CD2 3.74Å; I283-L451 HydrophobicContact CG1-CD2 4.03Å; I283-L451 HydrophobicContact CG2-CD2 3.75Å; C447-L451 PolarHBondContact O-N 3.4Å; L451-M453 PolarHBondContact O-N 2.86Å; L451-D454 PolarHBondContact O-N 2.9Å; L451-I455 HydrophobicContact CD1-CD1 3.81Å; L451-I455 HydrophobicContact CD1-CG1 4.25Å; L451-I455 HydrophobicContact CG-CD1 3.91Å; L451-I455 WeakPolarHBondContact O-CB 3.35Å; L451-I455 VanDerWaalsContact O-CD1 3.29Å; L451-I455 WeakPolarHBondContact O-CD1 3.2Å; L451-I455 WeakPolarHBondContact O-CG1 3.08Å; L451-I455 PolarHBondContact O-N 3.32Å; L451-I455 VanDerWaalsContact O-N 3.12Å
452	A	83.4	Confident	77.3	Confident	29 Å²	29	59.1 Å²	59.1	24%	0.24	31%	0.312	C	S	.	.	H	α-helix	trans	-64.3	-39.2	176.5	0	0	0	0	0	112.6	A448 A449 T456	A448-A452 WeakPolarHBondContact O-CB 3.21Å; A448-A452 PolarHBondContact O-N 2.83Å; A449-A452 PolarHBondContact O-N 3.44Å; A452-T456 WeakPolarHBondContact O-CB 2.9Å; A452-T456 VanDerWaalsContact O-CG2 3.27Å; A452-T456 WeakPolarHBondContact O-CG2 3.28Å; A452-T456 PolarHBondContact O-N 3.28Å; A452-T456 VanDerWaalsContact O-N 3.12Å; A452-T456 PolarHBondContact O-OG1 3Å
453	M	80.8	Confident	76	Confident	115 Å²	115	66.8 Å²	66.8	57%	0.567	34%	0.335	S	S	*	.	H	α-helix	trans	-67.1	-47.1	176.4	-76.8	-178.1	-179.3	0	0	111.2	A449 L450 L451 I455 T456 V457	A449-M453 VanDerWaalsContact O-CB 3.27Å; A449-M453 WeakPolarHBondContact O-CB 3.48Å; A449-M453 VanDerWaalsContact O-CG 3.23Å; A449-M453 WeakPolarHBondContact O-CG 3.47Å; A449-M453 PolarHBondContact O-N 3.49Å; L450-M453 PolarHBondContact O-N 3.31Å; L451-M453 PolarHBondContact O-N 2.86Å; M453-I455 PolarHBondContact O-N 2.98Å; M453-T456 WeakPolarHBondContact CA-OG1 3.21Å; M453-T456 CarbonylContact O-C 3.52Å; M453-T456 PolarHBondContact O-N 3.38Å; M453-T456 PolarHBondContact O-OG1 3.42Å; M453-T456 VanDerWaalsContact O-OG1 3.11Å; M453-V457 WeakPolarHBondContact O-CB 3Å; M453-V457 WeakPolarHBondContact O-CG2 3.43Å; M453-V457 PolarHBondContact O-N 3.42Å
454	D	75.3	Confident	75.1	Confident	64 Å²	64	72.3 Å²	72.3	34%	0.342	37%	0.369	S	S	.	.	H	α-helix	trans	-58.8	-42.1	180	-158.8	25.4	0	0	0	110.9	H192 L450 L451 T456	H192-D454 IonicContact CD2-OD2 3.97Å; H192-D454 IonicContact NE2-OD2 2.87Å; L450-D454 WeakPolarHBondContact O-CB 3.47Å; L450-D454 PolarHBondContact O-N 3.23Å; L451-D454 PolarHBondContact O-N 2.9Å; D454-T456 VanDerWaalsContact C-N 3.32Å; D454-T456 PolarHBondContact O-N 3.09Å
455	I	71.7	Confident	74.4	Confident	3 Å²	3	74.3 Å²	74.3	2%	0.015	39%	0.386	C	S	.	.	H	α-helix	trans	-63.8	-33.4	175.3	-68.9	168.1	0	0	0	113	V262 A263 V268 L451 M453	V262-I455 HydrophobicContact CG1-CG2 3.86Å; A263-I455 HydrophobicContact CB-CD1 4.19Å; V268-I455 HydrophobicContact CB-CG2 4.09Å; V268-I455 HydrophobicContact CG1-CG2 3.3Å; V268-I455 HydrophobicContact CG2-CG2 3.62Å; L451-I455 HydrophobicContact CD1-CD1 3.81Å; L451-I455 HydrophobicContact CD1-CG1 4.25Å; L451-I455 HydrophobicContact CG-CD1 3.91Å; L451-I455 WeakPolarHBondContact O-CB 3.35Å; L451-I455 VanDerWaalsContact O-CD1 3.29Å; L451-I455 WeakPolarHBondContact O-CD1 3.2Å; L451-I455 WeakPolarHBondContact O-CG1 3.08Å; L451-I455 PolarHBondContact O-N 3.32Å; L451-I455 VanDerWaalsContact O-N 3.12Å; M453-I455 PolarHBondContact O-N 2.98Å
456	T	70.9	Confident	74	Confident	54 Å²	54	75.6 Å²	75.6	33%	0.331	41%	0.406	S	S	.	.	H	α-helix	trans	-95.9	-27.1	-174.3	50.9	0	0	0	0	113.7	A452 M453 D454 E458 Q459	A452-T456 WeakPolarHBondContact O-CB 2.9Å; A452-T456 VanDerWaalsContact O-CG2 3.27Å; A452-T456 WeakPolarHBondContact O-CG2 3.28Å; A452-T456 PolarHBondContact O-N 3.28Å; A452-T456 VanDerWaalsContact O-N 3.12Å; A452-T456 PolarHBondContact O-OG1 3Å; M453-T456 WeakPolarHBondContact CA-OG1 3.21Å; M453-T456 CarbonylContact O-C 3.52Å; M453-T456 PolarHBondContact O-N 3.38Å; M453-T456 PolarHBondContact O-OG1 3.42Å; M453-T456 VanDerWaalsContact O-OG1 3.11Å; D454-T456 VanDerWaalsContact C-N 3.32Å; D454-T456 PolarHBondContact O-N 3.09Å; T456-E458 VanDerWaalsContact C-N 3.26Å; T456-E458 PolarHBondContact O-N 3.49Å; T456-Q459 VanDerWaalsContact O-CB 3.24Å; T456-Q459 WeakPolarHBondContact O-CB 3.5Å; T456-Q459 PolarHBondContact O-N 3.08Å
457	V	64.3	Low	73.8	Confident	74 Å²	74	76.1 Å²	76.1	45%	0.448	41%	0.406	S	S	.	.	H	α-helix	trans	-63.4	-34.4	-178.5	166	0	0	0	0	111.1	M453 Q459 M460	M453-V457 WeakPolarHBondContact O-CB 3Å; M453-V457 WeakPolarHBondContact O-CG2 3.43Å; M453-V457 PolarHBondContact O-N 3.42Å; V457-Q459 PolarHBondContact O-N 3.05Å; V457-M460 HydrophobicContact CB-CE 3.95Å; V457-M460 HydrophobicContact CG1-CE 3.98Å; V457-M460 HydrophobicContact CG2-CE 3.65Å; V457-M460 WeakPolarHBondContact O-CB 3.48Å; V457-M460 PolarHBondContact O-N 3.22Å
458	E	60.4	Low	73.7	Confident	85 Å²	85	80.8 Å²	80.8	40%	0.397	43%	0.431	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-15.3	175.2	-65.9	-167.5	172.2	0	0	113.6	Q272 T456 M460	Q272-E458 VanDerWaalsContact CB-OE2 3.29Å; Q272-E458 WeakPolarHBondContact CB-OE2 3.33Å; Q272-E458 WeakPolarHBondContact CG-OE2 3.39Å; Q272-E458 PolarHBondContact NE2-OE1 3.24Å; Q272-E458 PolarHBondContact NE2-OE2 3.37Å; T456-E458 VanDerWaalsContact C-N 3.26Å; T456-E458 PolarHBondContact O-N 3.49Å; E458-M460 VanDerWaalsContact C-N 3.26Å
459	Q	57.8	Low	73.5	Confident	67 Å²	67	83.8 Å²	83.8	31%	0.313	45%	0.451	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.2	-15.9	170.8	-54.9	-175.7	-39.6	0	0	112.3	S267 V268 Y271 T456 V457 S461	S267-Q459 PolarHBondContact O-NE2 3.16Å; V268-Q459 VanDerWaalsContact CG2-NE2 3.33Å; Y271-Q459 HydrophobicContact CD2-CB 4.22Å; Y271-Q459 HydrophobicContact CD2-CG 3.85Å; Y271-Q459 HydrophobicContact CE2-CB 4.39Å; Y271-Q459 HydrophobicContact CE2-CG 4.37Å; Y271-Q459 HydrophobicContact CG-CG 4.38Å; T456-Q459 VanDerWaalsContact O-CB 3.24Å; T456-Q459 WeakPolarHBondContact O-CB 3.5Å; T456-Q459 PolarHBondContact O-N 3.08Å; V457-Q459 PolarHBondContact O-N 3.05Å; Q459-S461 PolarHBondContact O-N 3.35Å
460	M	58.1	Low	73.5	Confident	132 Å²	132	87.5 Å²	87.5	65%	0.65	47%	0.468	S	S	*	.	S	Bend	trans	-77.1	121.2	177.4	-65.4	-167.9	-87.2	0	0	110.1	V457 E458 R462	V457-M460 HydrophobicContact CB-CE 3.95Å; V457-M460 HydrophobicContact CG1-CE 3.98Å; V457-M460 HydrophobicContact CG2-CE 3.65Å; V457-M460 WeakPolarHBondContact O-CB 3.48Å; V457-M460 PolarHBondContact O-N 3.22Å; E458-M460 VanDerWaalsContact C-N 3.26Å; M460-R462 PolarHBondContact O-N 3.1Å
461	S	57	Low	73.8	Confident	112 Å²	112	88 Å²	88	78%	0.783	47%	0.474	S	S	*	.	P	Polyproline II helix	trans	-58.5	137.2	171.7	56.3	0	0	0	0	110.2	Q459 Y463	Q459-S461 PolarHBondContact O-N 3.35Å; S461-Y463 PolarHBondContact O-N 3.21Å
462	R	59.8	Low	74.1	Confident	233 Å²	233	89.2 Å²	89.2	88%	0.879	48%	0.478	S	S	*	.	P	Polyproline II helix	trans	-51.7	127.7	172.1	-113.7	-177.8	-90	-172.2	-6.1	109.4	M460 T464	M460-R462 PolarHBondContact O-N 3.1Å; R462-T464 PolarHBondContact O-N 3.09Å
463	Y	65.1	Low	74.6	Confident	194 Å²	194	89.8 Å²	89.8	76%	0.761	48%	0.479	S	S	*	.			trans	-61.6	109.8	174.1	176.8	-96.1	0	0	0	108.9	S461 P466	S461-Y463 PolarHBondContact O-N 3.21Å; Y463-P466 WeakPolarHBondContact OH-CD 3.27Å
464	T	68.5	Low	75.2	Confident	116 Å²	116	87.1 Å²	87.1	71%	0.712	48%	0.476	S	S	*	.			trans	-90.7	128.5	168.9	48.8	0	0	0	0	107.6	R462	R462-T464 PolarHBondContact O-N 3.09Å
465	A	77	Confident	75.9	Confident	43 Å²	43	86.8 Å²	86.8	36%	0.355	47%	0.473	S	S	.	.			trans	-56.3	135.9	174.7	0	0	0	0	0	109	I467	A465-I467 PolarHBondContact O-N 3.47Å; A465-I467 VanDerWaalsContact O-N 3.11Å
466	P	83.3	Confident	76.9	Confident	118 Å²	118	86.7 Å²	86.7	77%	0.766	47%	0.473	S	S	*	.	S	Bend	trans	-61.8	-24.3	-174.4	23.5	-34.2	0	0	0	112.8	Y463	Y463-P466 WeakPolarHBondContact OH-CD 3.27Å
467	I	85.3	Confident	78.1	Confident	61 Å²	61	87.4 Å²	87.4	31%	0.313	48%	0.477	S	S	.	.	S	Bend	trans	-125.3	128	174.2	-61.2	170.4	0	0	0	107.4	A465 V471 Y472 F524	A465-I467 PolarHBondContact O-N 3.47Å; A465-I467 VanDerWaalsContact O-N 3.11Å; I467-V471 HydrophobicContact CG2-CB 4.49Å; I467-Y472 HydrophobicContact CB-CE1 4.07Å; I467-Y472 HydrophobicContact CG2-CD1 4.03Å; I467-Y472 HydrophobicContact CG2-CE1 3.79Å; I467-F524 HydrophobicContact CD1-CE1 3.81Å; I467-F524 HydrophobicContact CD1-CZ 3.45Å; I467-F524 VanDerWaalsContact CD1-CZ 3.45Å; I467-F524 HydrophobicContact CG2-CE1 4.34Å
468	N	83.9	Confident	79.6	Confident	97 Å²	97	87.6 Å²	87.6	52%	0.519	48%	0.479	S	S	.	.			trans	-64.1	128	179.1	-175.1	-29.5	0	0	0	109.9	V470 V471	N468-V470 PolarHBondContact O-N 2.84Å; N468-V470 WeakPolarHBondContact OD1-CB 3.37Å; N468-V470 WeakPolarHBondContact OD1-CG2 3.25Å; N468-V470 PolarHBondContact OD1-N 3.33Å; N468-V471 HydrophobicContact CB-CG2 4.26Å; N468-V471 WeakPolarHBondContact O-CB 3.36Å; N468-V471 PolarHBondContact O-N 3.39Å
469	P	84.4	Confident	81.2	Confident	68 Å²	68	85 Å²	85	44%	0.442	47%	0.467	S	S	.	.	G	3₁₀ helix	trans	-53.2	-26.5	179.1	-28.3	35	0	0	0	115.2	V471 Y472	P469-V471 PolarHBondContact O-N 3.19Å; P469-Y472 HydrophobicContact CB-CD2 4.1Å; P469-Y472 HydrophobicContact CB-CE2 3.86Å; P469-Y472 HydrophobicContact CG-CE2 4.17Å; P469-Y472 WeakPolarHBondContact O-CB 3.46Å; P469-Y472 PolarHBondContact O-N 2.87Å
470	V	88	Confident	83	Confident	120 Å²	120	83.4 Å²	83.4	73%	0.727	46%	0.461	S	S	*	.	G	3₁₀ helix	trans	-60.4	-26.9	175.5	177.9	0	0	0	0	112	N468 P473	N468-V470 PolarHBondContact O-N 2.84Å; N468-V470 WeakPolarHBondContact OD1-CB 3.37Å; N468-V470 WeakPolarHBondContact OD1-CG2 3.25Å; N468-V470 PolarHBondContact OD1-N 3.33Å; V470-P473 WeakPolarHBondContact O-CD 3.46Å
471	V	90.8	Very high	84.9	Confident	62 Å²	62	82.6 Å²	82.6	38%	0.376	46%	0.459	S	S	.	.	G	3₁₀ helix	trans	-89	-13.7	-177.7	-166.2	0	0	0	0	112	I467 N468 P469 P473 A474 L475	I467-V471 HydrophobicContact CG2-CB 4.49Å; N468-V471 HydrophobicContact CB-CG2 4.26Å; N468-V471 WeakPolarHBondContact O-CB 3.36Å; N468-V471 PolarHBondContact O-N 3.39Å; P469-V471 PolarHBondContact O-N 3.19Å; V471-P473 VanDerWaalsContact C-CD 3.47Å; V471-A474 PolarHBondContact O-N 2.96Å; V471-L475 HydrophobicContact CG1-CD1 3.89Å; V471-L475 WeakPolarHBondContact O-CB 3.48Å; V471-L475 PolarHBondContact O-N 3.01Å
472	Y	90.3	Very high	86.7	Confident	26 Å²	26	80.1 Å²	80.1	10%	0.102	44%	0.436	C	S	.	.	H	α-helix	trans	-53.8	-45.1	-177.7	-64.6	-11.4	0	0	0	114	I467 P469 L475 S476 F524 L527	I467-Y472 HydrophobicContact CB-CE1 4.07Å; I467-Y472 HydrophobicContact CG2-CD1 4.03Å; I467-Y472 HydrophobicContact CG2-CE1 3.79Å; P469-Y472 HydrophobicContact CB-CD2 4.1Å; P469-Y472 HydrophobicContact CB-CE2 3.86Å; P469-Y472 HydrophobicContact CG-CE2 4.17Å; P469-Y472 WeakPolarHBondContact O-CB 3.46Å; P469-Y472 PolarHBondContact O-N 2.87Å; Y472-L475 PolarHBondContact O-N 3.24Å; Y472-S476 VanDerWaalsContact O-CB 3.22Å; Y472-S476 WeakPolarHBondContact O-CB 3.44Å; Y472-S476 PolarHBondContact O-N 3.38Å; Y472-F524 AromaticContact CD1-CD1 3.86Å; Y472-F524 HydrophobicContact CD1-CD1 3.86Å; Y472-F524 AromaticContact CD1-CE1 3.99Å; Y472-F524 HydrophobicContact CD1-CE1 3.99Å; Y472-F524 HydrophobicContact CE1-CD1 4.38Å; Y472-F524 HydrophobicContact CE1-CE1 4.15Å; Y472-F524 HydrophobicContact CG-CD1 4.38Å; Y472-L527 HydrophobicContact CD2-CB 4.11Å; Y472-L527 HydrophobicContact CE2-CB 4.2Å
473	P	92.9	Very high	88.4	Confident	41 Å²	41	69 Å²	69	27%	0.266	39%	0.394	S	S	.	.	H	α-helix	trans	-63.7	-45.3	179.5	-19.3	32	0	0	0	112.1	V470 V471 S476 V477 W528	V470-P473 WeakPolarHBondContact O-CD 3.46Å; V471-P473 VanDerWaalsContact C-CD 3.47Å; P473-S476 PolarHBondContact O-N 2.8Å; P473-V477 WeakPolarHBondContact O-CG2 3.3Å; P473-V477 PolarHBondContact O-N 3.1Å; P473-W528 HydrophobicContact CB-CD2 3.89Å; P473-W528 HydrophobicContact CB-CE3 4.2Å; P473-W528 HydrophobicContact CB-CG 4.41Å; P473-W528 HydrophobicContact CB-CH2 4.23Å; P473-W528 HydrophobicContact CB-CZ2 3.91Å; P473-W528 HydrophobicContact CB-CZ3 4.37Å; P473-W528 HydrophobicContact CG-CD2 4.1Å; P473-W528 HydrophobicContact CG-CG 4.14Å; P473-W528 HydrophobicContact CG-CZ2 4.4Å
474	A	93.5	Very high	89.8	Confident	59 Å²	59	64.8 Å²	64.8	49%	0.488	38%	0.384	S	S	.	.	H	α-helix	trans	-65.6	-42.6	-179	0	0	0	0	0	111.7	V471 T478	V471-A474 PolarHBondContact O-N 2.96Å; A474-T478 VanDerWaalsContact O-CB 3.29Å; A474-T478 WeakPolarHBondContact O-CB 3.33Å; A474-T478 PolarHBondContact O-N 3.16Å; A474-T478 PolarHBondContact O-OG1 3.09Å
475	L	90.9	Very high	91.1	Very high	57 Å²	57	64.9 Å²	64.9	30%	0.298	38%	0.375	S	S	.	.	H	α-helix	trans	-66.8	-43.6	177.8	-134.8	102.5	0	0	0	111.1	V471 Y472 T478 L479 F524	V471-L475 HydrophobicContact CG1-CD1 3.89Å; V471-L475 WeakPolarHBondContact O-CB 3.48Å; V471-L475 PolarHBondContact O-N 3.01Å; Y472-L475 PolarHBondContact O-N 3.24Å; L475-T478 PolarHBondContact O-N 2.97Å; L475-L479 HydrophobicContact CD2-CD1 3.7Å; L475-L479 HydrophobicContact CG-CD1 4.14Å; L475-L479 VanDerWaalsContact O-CB 3.29Å; L475-L479 WeakPolarHBondContact O-CB 3.19Å; L475-L479 WeakPolarHBondContact O-CG 3.44Å; L475-L479 PolarHBondContact O-N 3.39Å; L475-F524 HydrophobicContact CB-CG 4.42Å; L475-F524 HydrophobicContact CD2-CD1 4.18Å; L475-F524 HydrophobicContact CD2-CD2 3.58Å; L475-F524 HydrophobicContact CD2-CE1 3.9Å; L475-F524 HydrophobicContact CD2-CE2 3.26Å; L475-F524 HydrophobicContact CD2-CG 4.04Å; L475-F524 HydrophobicContact CD2-CZ 3.45Å; L475-F524 VanDerWaalsContact CD2-CZ 3.45Å
476	S	93.5	Very high	91.9	Very high	1 Å²	1	65.5 Å²	65.5	1%	0.007	37%	0.37	C	S	.	.	H	α-helix	trans	-58.3	-52.8	177.5	-177.5	0	0	0	0	111.4	Y472 P473 T478 L480 G521 L525	Y472-S476 VanDerWaalsContact O-CB 3.22Å; Y472-S476 WeakPolarHBondContact O-CB 3.44Å; Y472-S476 PolarHBondContact O-N 3.38Å; P473-S476 PolarHBondContact O-N 2.8Å; S476-T478 PolarHBondContact O-N 3.29Å; S476-L480 VanDerWaalsContact O-CB 3.27Å; S476-L480 WeakPolarHBondContact O-CB 3.43Å; S476-L480 VanDerWaalsContact O-CG 3.25Å; S476-L480 WeakPolarHBondContact O-CG 3.33Å; S476-L480 PolarHBondContact O-N 3.16Å; S476-G521 PolarHBondContact OG-O 3.08Å; S476-L525 VanDerWaalsContact OG-CA 3.31Å; S476-L525 WeakPolarHBondContact OG-CA 3.32Å; S476-L525 WeakPolarHBondContact OG-CB 3.33Å; S476-L525 PolarHBondContact OG-N 3.37Å
477	V	95.2	Very high	92.4	Very high	70 Å²	70	61.7 Å²	61.7	42%	0.424	34%	0.344	S	S	.	.	H	α-helix	trans	-62.2	-45.9	-179.6	172.5	0	0	0	0	111	P473 L480 L481 W528	P473-V477 WeakPolarHBondContact O-CG2 3.3Å; P473-V477 PolarHBondContact O-N 3.1Å; V477-L480 PolarHBondContact O-N 3.11Å; V477-L481 HydrophobicContact CG1-CD1 3.81Å; V477-L481 HydrophobicContact CG1-CG 4.31Å; V477-L481 WeakPolarHBondContact O-CB 3.45Å; V477-L481 VanDerWaalsContact O-CG 3.25Å; V477-L481 WeakPolarHBondContact O-CG 3.24Å; V477-L481 PolarHBondContact O-N 3.14Å; V477-W528 HydrophobicContact CG2-CZ3 4.32Å
478	T	95	Very high	92.9	Very high	78 Å²	78	61.3 Å²	61.3	48%	0.479	35%	0.35	S	S	.	.	H	α-helix	trans	-63.9	-47.9	-177.7	-55.2	0	0	0	0	111.6	A474 L475 S476 L481 I482	A474-T478 VanDerWaalsContact O-CB 3.29Å; A474-T478 WeakPolarHBondContact O-CB 3.33Å; A474-T478 PolarHBondContact O-N 3.16Å; A474-T478 PolarHBondContact O-OG1 3.09Å; L475-T478 PolarHBondContact O-N 2.97Å; S476-T478 PolarHBondContact O-N 3.29Å; T478-L481 PolarHBondContact O-N 3.31Å; T478-I482 HydrophobicContact CG2-CD1 4.01Å; T478-I482 VanDerWaalsContact O-CG1 3.31Å; T478-I482 WeakPolarHBondContact O-CG1 3.23Å; T478-I482 PolarHBondContact O-N 3.16Å; T478-I482 VanDerWaalsContact O-N 3.09Å
479	L	95	Very high	93.3	Very high	30 Å²	30	62.9 Å²	62.9	16%	0.157	35%	0.349	C	S	.	.	H	α-helix	trans	-67.8	-39.2	-179	-67.6	174.5	0	0	0	112	L475 I482 G483 F517 V520 F524	L475-L479 HydrophobicContact CD2-CD1 3.7Å; L475-L479 HydrophobicContact CG-CD1 4.14Å; L475-L479 VanDerWaalsContact O-CB 3.29Å; L475-L479 WeakPolarHBondContact O-CB 3.19Å; L475-L479 WeakPolarHBondContact O-CG 3.44Å; L475-L479 PolarHBondContact O-N 3.39Å; L479-I482 PolarHBondContact O-N 3.03Å; L479-G483 PolarHBondContact O-N 3.4Å; L479-F517 HydrophobicContact CD2-CD1 3.55Å; L479-F517 HydrophobicContact CD2-CE1 3.68Å; L479-V520 HydrophobicContact CD1-CB 4.33Å; L479-V520 HydrophobicContact CD1-CG1 3.71Å; L479-F524 HydrophobicContact CD1-CD2 3.93Å; L479-F524 HydrophobicContact CD1-CE2 4.24Å
480	L	96.2	Very high	93.8	Very high	34 Å²	34	62 Å²	62	18%	0.178	34%	0.338	C	S	.	.	H	α-helix	trans	-67	-40	175.6	-73.2	174	0	0	0	112	S476 V477 G483 L484 L525	S476-L480 VanDerWaalsContact O-CB 3.27Å; S476-L480 WeakPolarHBondContact O-CB 3.43Å; S476-L480 VanDerWaalsContact O-CG 3.25Å; S476-L480 WeakPolarHBondContact O-CG 3.33Å; S476-L480 PolarHBondContact O-N 3.16Å; V477-L480 PolarHBondContact O-N 3.11Å; L480-G483 PolarHBondContact O-N 3.1Å; L480-L484 VanDerWaalsContact O-CB 3.26Å; L480-L484 WeakPolarHBondContact O-CB 3.36Å; L480-L484 WeakPolarHBondContact O-CG 3.39Å; L480-L484 PolarHBondContact O-N 3Å; L480-L525 HydrophobicContact CD1-CB 4.28Å; L480-L525 HydrophobicContact CD1-CD2 4.07Å
481	L	96.6	Very high	94	Very high	114 Å²	114	62.3 Å²	62.3	60%	0.597	33%	0.33	S	S	*	.	H	α-helix	trans	-62.1	-44.9	175.9	-75.9	174	0	0	0	111.8	V477 T478 F485	V477-L481 HydrophobicContact CG1-CD1 3.81Å; V477-L481 HydrophobicContact CG1-CG 4.31Å; V477-L481 WeakPolarHBondContact O-CB 3.45Å; V477-L481 VanDerWaalsContact O-CG 3.25Å; V477-L481 WeakPolarHBondContact O-CG 3.24Å; V477-L481 PolarHBondContact O-N 3.14Å; T478-L481 PolarHBondContact O-N 3.31Å; L481-F485 WeakPolarHBondContact O-CB 3.46Å; L481-F485 PolarHBondContact O-N 3.44Å
482	I	95.3	Very high	94.2	Very high	61 Å²	61	63.7 Å²	63.7	31%	0.313	34%	0.338	S	S	.	.	H	α-helix	trans	-63.6	-46.4	175.8	-64.9	166.9	0	0	0	110.4	T478 L479 L484 F485 F486 F517	T478-I482 HydrophobicContact CG2-CD1 4.01Å; T478-I482 VanDerWaalsContact O-CG1 3.31Å; T478-I482 WeakPolarHBondContact O-CG1 3.23Å; T478-I482 PolarHBondContact O-N 3.16Å; T478-I482 VanDerWaalsContact O-N 3.09Å; L479-I482 PolarHBondContact O-N 3.03Å; I482-L484 PolarHBondContact O-N 2.81Å; I482-F485 WeakPolarHBondContact O-CB 3.42Å; I482-F485 PolarHBondContact O-N 3.26Å; I482-F486 HydrophobicContact CG2-CD2 3.77Å; I482-F486 HydrophobicContact CG2-CE2 3.7Å; I482-F486 VanDerWaalsContact O-CD2 3.27Å; I482-F486 WeakPolarHBondContact O-CD2 3.37Å; I482-F486 PolarHBondContact O-N 2.83Å; I482-F486 VanDerWaalsContact O-N 3.08Å; I482-F517 HydrophobicContact CB-CD1 4.01Å; I482-F517 HydrophobicContact CB-CE1 4.39Å; I482-F517 HydrophobicContact CB-CG 4.41Å; I482-F517 HydrophobicContact CD1-CD1 4.49Å; I482-F517 HydrophobicContact CD1-CE1 4.18Å; I482-F517 HydrophobicContact CG2-CB 4.48Å; I482-F517 HydrophobicContact CG2-CD1 3.69Å; I482-F517 HydrophobicContact CG2-CD2 4.11Å; I482-F517 HydrophobicContact CG2-CE1 3.86Å; I482-F517 HydrophobicContact CG2-CE2 4.27Å; I482-F517 HydrophobicContact CG2-CG 3.83Å; I482-F517 HydrophobicContact CG2-CZ 4.15Å
483	G	95.4	Very high	94.2	Very high	0 Å²	0	64 Å²	64	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-61.3	-43.4	178.8	0	0	0	0	0	113	L479 L480 F486 T487	L479-G483 PolarHBondContact O-N 3.4Å; L480-G483 PolarHBondContact O-N 3.1Å; G483-F486 PolarHBondContact O-N 3.4Å; G483-T487 WeakPolarHBondContact O-CB 3.47Å; G483-T487 PolarHBondContact O-N 3.18Å; G483-T487 PolarHBondContact O-OG1 3.24Å
484	L	94.9	Very high	94.1	Very high	105 Å²	105	64.3 Å²	64.3	55%	0.55	34%	0.337	S	S	.	.	H	α-helix	trans	-66.9	-37.3	176.4	-72.9	173.4	0	0	0	112	L480 I482 T487 A488	L480-L484 VanDerWaalsContact O-CB 3.26Å; L480-L484 WeakPolarHBondContact O-CB 3.36Å; L480-L484 WeakPolarHBondContact O-CG 3.39Å; L480-L484 PolarHBondContact O-N 3Å; I482-L484 PolarHBondContact O-N 2.81Å; L484-T487 PolarHBondContact O-N 2.96Å; L484-A488 WeakPolarHBondContact O-CB 3.48Å; L484-A488 PolarHBondContact O-N 3.47Å
485	F	95.9	Very high	94.1	Very high	117 Å²	117	67.6 Å²	67.6	51%	0.513	35%	0.351	S	S	.	.	H	α-helix	trans	-60	-49.6	173.7	172.4	-95.9	0	0	0	111.7	L481 I482 T487 A488 W489	L481-F485 WeakPolarHBondContact O-CB 3.46Å; L481-F485 PolarHBondContact O-N 3.44Å; I482-F485 WeakPolarHBondContact O-CB 3.42Å; I482-F485 PolarHBondContact O-N 3.26Å; F485-T487 VanDerWaalsContact C-N 3.34Å; F485-T487 PolarHBondContact O-N 3.48Å; F485-A488 PolarHBondContact O-N 3.42Å; F485-W489 AromaticContact CE1-CE3 3.83Å; F485-W489 HydrophobicContact CE1-CE3 3.83Å; F485-W489 HydrophobicContact CE1-CZ3 4.28Å; F485-W489 HydrophobicContact CE2-CE3 4.39Å; F485-W489 AromaticContact CZ-CE3 3.55Å; F485-W489 HydrophobicContact CZ-CE3 3.55Å; F485-W489 AromaticContact CZ-CZ3 3.79Å; F485-W489 HydrophobicContact CZ-CZ3 3.79Å; F485-W489 PolarHBondContact O-N 3.47Å
486	F	94.1	Very high	94.1	Very high	57 Å²	57	69.8 Å²	69.8	25%	0.25	37%	0.367	C	S	.	.	H	α-helix	trans	-67.5	-34.5	177.9	-78.2	-68.6	0	0	0	112.7	I482 G483 W489 F490 L510 V513 A514	I482-F486 HydrophobicContact CG2-CD2 3.77Å; I482-F486 HydrophobicContact CG2-CE2 3.7Å; I482-F486 VanDerWaalsContact O-CD2 3.27Å; I482-F486 WeakPolarHBondContact O-CD2 3.37Å; I482-F486 PolarHBondContact O-N 2.83Å; I482-F486 VanDerWaalsContact O-N 3.08Å; G483-F486 PolarHBondContact O-N 3.4Å; F486-W489 PolarHBondContact O-N 3.08Å; F486-F490 WeakPolarHBondContact O-CB 3.36Å; F486-F490 PolarHBondContact O-N 3.49Å; F486-L510 HydrophobicContact CD1-CD1 3.6Å; F486-L510 HydrophobicContact CE1-CD1 4.21Å; F486-V513 HydrophobicContact CD1-CG1 4.23Å; F486-V513 HydrophobicContact CD2-CG1 3.74Å; F486-V513 HydrophobicContact CE1-CG1 4.29Å; F486-V513 HydrophobicContact CE2-CG1 3.82Å; F486-V513 HydrophobicContact CG-CG1 3.96Å; F486-V513 HydrophobicContact CZ-CG1 4.1Å; F486-A514 HydrophobicContact CB-CB 3.85Å
487	T	94	Very high	93.6	Very high	38 Å²	38	70.5 Å²	70.5	23%	0.233	37%	0.374	C	S	.	.	H	α-helix	trans	-63.4	-45.9	173.8	-57.4	0	0	0	0	111	G483 L484 F485 F490 F491	G483-T487 WeakPolarHBondContact O-CB 3.47Å; G483-T487 PolarHBondContact O-N 3.18Å; G483-T487 PolarHBondContact O-OG1 3.24Å; L484-T487 PolarHBondContact O-N 2.96Å; F485-T487 VanDerWaalsContact C-N 3.34Å; F485-T487 PolarHBondContact O-N 3.48Å; T487-F490 WeakPolarHBondContact O-CB 3.35Å; T487-F490 PolarHBondContact O-N 3.34Å; T487-F491 HydrophobicContact CG2-CD2 3.9Å; T487-F491 HydrophobicContact CG2-CE2 3.55Å; T487-F491 WeakPolarHBondContact O-CD2 3.35Å; T487-F491 PolarHBondContact O-N 3.31Å; T487-F491 VanDerWaalsContact O-N 3.09Å
488	A	95.2	Very high	93.1	Very high	52 Å²	52	72.6 Å²	72.6	43%	0.43	38%	0.383	S	S	.	.	H	α-helix	trans	-63.7	-42.7	175.7	0	0	0	0	0	111.7	L484 F485 F490 F491 V492	L484-A488 WeakPolarHBondContact O-CB 3.48Å; L484-A488 PolarHBondContact O-N 3.47Å; F485-A488 PolarHBondContact O-N 3.42Å; A488-F490 VanDerWaalsContact C-N 3.28Å; A488-F490 PolarHBondContact O-N 3.46Å; A488-F491 PolarHBondContact O-N 2.79Å; A488-V492 VanDerWaalsContact O-CG2 3.3Å; A488-V492 WeakPolarHBondContact O-CG2 3.46Å; A488-V492 PolarHBondContact O-N 3.39Å
489	W	93.3	Very high	92.6	Very high	130 Å²	130	77.9 Å²	77.9	49%	0.492	40%	0.4	S	S	.	.	H	α-helix	trans	-57.8	-43.4	174.2	-168.4	-55.1	0	0	0	111	F485 F486 V492 Y493 L510	F485-W489 AromaticContact CE1-CE3 3.83Å; F485-W489 HydrophobicContact CE1-CE3 3.83Å; F485-W489 HydrophobicContact CE1-CZ3 4.28Å; F485-W489 HydrophobicContact CE2-CE3 4.39Å; F485-W489 AromaticContact CZ-CE3 3.55Å; F485-W489 HydrophobicContact CZ-CE3 3.55Å; F485-W489 AromaticContact CZ-CZ3 3.79Å; F485-W489 HydrophobicContact CZ-CZ3 3.79Å; F485-W489 PolarHBondContact O-N 3.47Å; F486-W489 PolarHBondContact O-N 3.08Å; W489-V492 PolarHBondContact O-N 3.46Å; W489-Y493 WeakPolarHBondContact O-CB 3.46Å; W489-Y493 PolarHBondContact O-N 3.33Å; W489-L510 HydrophobicContact CB-CD2 4.33Å; W489-L510 VanDerWaalsContact CD1-CD2 3.44Å; W489-L510 HydrophobicContact CG-CD1 4.3Å; W489-L510 HydrophobicContact CG-CD2 4.13Å
490	F	93	Very high	92	Very high	49 Å²	49	86 Å²	86	22%	0.215	43%	0.434	C	S	.	.	H	α-helix	trans	-60.7	-48.7	179	177	-95.7	0	0	0	111.7	F486 T487 A488 V492 Y493 E494 E507 L510 A511	F486-F490 WeakPolarHBondContact O-CB 3.36Å; F486-F490 PolarHBondContact O-N 3.49Å; T487-F490 WeakPolarHBondContact O-CB 3.35Å; T487-F490 PolarHBondContact O-N 3.34Å; A488-F490 VanDerWaalsContact C-N 3.28Å; A488-F490 PolarHBondContact O-N 3.46Å; F490-V492 PolarHBondContact O-N 2.78Å; F490-Y493 PolarHBondContact O-N 3.22Å; F490-E494 HydrophobicContact CD1-CG 4.43Å; F490-E494 HydrophobicContact CE1-CG 3.97Å; F490-E494 HydrophobicContact CE2-CG 4.34Å; F490-E494 HydrophobicContact CZ-CG 3.91Å; F490-E494 PolarHBondContact O-N 3.15Å; F490-E507 HydrophobicContact CE2-CB 4.27Å; F490-L510 HydrophobicContact CB-CD2 3.7Å; F490-L510 HydrophobicContact CB-CG 4.11Å; F490-L510 HydrophobicContact CD2-CB 4.38Å; F490-L510 HydrophobicContact CD2-CD2 4.12Å; F490-L510 HydrophobicContact CD2-CG 4.47Å; F490-L510 HydrophobicContact CG-CD2 4.42Å; F490-A511 HydrophobicContact CD2-CB 4.16Å; F490-A511 HydrophobicContact CE2-CB 3.96Å; F490-A511 HydrophobicContact CZ-CB 4.48Å
491	F	94	Very high	91.5	Very high	128 Å²	128	88.6 Å²	88.6	56%	0.561	45%	0.451	S	S	*	.	H	α-helix	trans	-63	-39.6	176.5	-73.8	-61.9	0	0	0	113	T487 A488 Y493 E494 V495	T487-F491 HydrophobicContact CG2-CD2 3.9Å; T487-F491 HydrophobicContact CG2-CE2 3.55Å; T487-F491 WeakPolarHBondContact O-CD2 3.35Å; T487-F491 PolarHBondContact O-N 3.31Å; T487-F491 VanDerWaalsContact O-N 3.09Å; A488-F491 PolarHBondContact O-N 2.79Å; F491-Y493 VanDerWaalsContact C-N 3.35Å; F491-Y493 PolarHBondContact O-N 2.92Å; F491-E494 PolarHBondContact O-N 3.47Å; F491-V495 VanDerWaalsContact O-CG2 3.29Å; F491-V495 WeakPolarHBondContact O-CG2 3.43Å; F491-V495 PolarHBondContact O-N 2.88Å
492	V	93.1	Very high	90.9	Very high	90 Å²	90	87.8 Å²	87.8	55%	0.545	44%	0.44	S	S	.	.	H	α-helix	trans	-64.7	-39.9	175.8	172	0	0	0	0	111.3	A488 W489 F490 V495 T496	A488-V492 VanDerWaalsContact O-CG2 3.3Å; A488-V492 WeakPolarHBondContact O-CG2 3.46Å; A488-V492 PolarHBondContact O-N 3.39Å; W489-V492 PolarHBondContact O-N 3.46Å; F490-V492 PolarHBondContact O-N 2.78Å; V492-V495 PolarHBondContact O-N 3.32Å; V492-T496 VanDerWaalsContact O-CB 3.29Å; V492-T496 WeakPolarHBondContact O-CB 3.44Å; V492-T496 PolarHBondContact O-N 3.33Å; V492-T496 PolarHBondContact O-OG1 2.88Å
493	Y	91	Very high	90.6	Very high	32 Å²	32	90 Å²	90	13%	0.125	45%	0.453	C	S	.	.	H	α-helix	trans	-65	-41	176.8	-175.4	-100.4	0	0	0	111.8	W489 F490 F491 G497 T501 N503 K506 E507	W489-Y493 WeakPolarHBondContact O-CB 3.46Å; W489-Y493 PolarHBondContact O-N 3.33Å; F490-Y493 PolarHBondContact O-N 3.22Å; F491-Y493 VanDerWaalsContact C-N 3.35Å; F491-Y493 PolarHBondContact O-N 2.92Å; Y493-G497 WeakPolarHBondContact O-CA 3.35Å; Y493-G497 PolarHBondContact O-N 3.31Å; Y493-T501 PolarHBondContact OH-O 2.89Å; Y493-N503 PolarHBondContact OH-N 3.48Å; Y493-K506 HydrophobicContact CE2-CD 4.05Å; Y493-E507 HydrophobicContact CD1-CG 3.97Å; Y493-E507 HydrophobicContact CE1-CG 3.59Å
494	E	90.9	Very high	90.4	Very high	49 Å²	49	95.9 Å²	95.9	23%	0.229	48%	0.484	C	S	.	.	H	α-helix	trans	-64.3	-41.9	175.4	-78	-65	142.5	0	0	112.8	F490 F491 R502 E507	F490-E494 HydrophobicContact CD1-CG 4.43Å; F490-E494 HydrophobicContact CE1-CG 3.97Å; F490-E494 HydrophobicContact CE2-CG 4.34Å; F490-E494 HydrophobicContact CZ-CG 3.91Å; F490-E494 PolarHBondContact O-N 3.15Å; F491-E494 PolarHBondContact O-N 3.47Å; E494-R502 IonicContact OE1-CZ 3.51Å; E494-R502 IonicContact OE1-NH2 2.8Å; E494-R502 PolarHBondContact OE1-NH2 3.35Å; E494-R502 IonicContact OE2-CZ 3.03Å; E494-R502 IonicContact OE2-NH1 2.74Å; E494-R502 PolarHBondContact OE2-NH1 2.86Å; E494-R502 IonicContact OE2-NH2 2.78Å; E494-R502 PolarHBondContact OE2-NH2 2.04Å; E494-E507 VanDerWaalsContact OE1-CD 3.28Å
495	V	92.6	Very high	90.1	Very high	127 Å²	127	97 Å²	97	77%	0.77	49%	0.49	S	S	*	.	H	α-helix	trans	-77.5	-34.1	-177.3	175.1	0	0	0	0	112.4	F491 V492	F491-V495 VanDerWaalsContact O-CG2 3.29Å; F491-V495 WeakPolarHBondContact O-CG2 3.43Å; F491-V495 PolarHBondContact O-N 2.88Å; V492-V495 PolarHBondContact O-N 3.32Å
496	T	91.3	Very high	89.9	Confident	103 Å²	103	96.2 Å²	96.2	63%	0.632	49%	0.486	S	S	*	.	H	α-helix	trans	-89.5	-19	-178.1	-41.7	0	0	0	0	112.5	V492 N498	V492-T496 VanDerWaalsContact O-CB 3.29Å; V492-T496 WeakPolarHBondContact O-CB 3.44Å; V492-T496 PolarHBondContact O-N 3.33Å; V492-T496 PolarHBondContact O-OG1 2.88Å; T496-N498 PolarHBondContact O-N 2.9Å
497	G	82.8	Confident	89.8	Confident	16 Å²	16	94.5 Å²	94.5	17%	0.165	48%	0.478	C	S	.	.			trans	-76.9	111.7	-175.1	0	0	0	0	0	113.1	Y493	Y493-G497 WeakPolarHBondContact O-CA 3.35Å; Y493-G497 PolarHBondContact O-N 3.31Å
498	N	85.2	Confident	89.8	Confident	114 Å²	114	98.5 Å²	98.5	61%	0.61	50%	0.496	S	S	*	.			trans	-68.5	156.5	168.6	-74.1	-12.7	0	0	0	111	T496 F500 T501 R502	T496-N498 PolarHBondContact O-N 2.9Å; N498-F500 PolarHBondContact O-N 2.76Å; N498-T501 PolarHBondContact N-OG1 3.49Å; N498-T501 PolarHBondContact O-N 2.72Å; N498-T501 PolarHBondContact O-OG1 2.89Å; N498-T501 VanDerWaalsContact O-OG1 3.07Å; N498-R502 PolarHBondContact O-N 3.3Å
499	K	84.5	Confident	89.7	Confident	190 Å²	190	100.7 Å²	100.7	83%	0.826	50%	0.499	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51	-26.6	179.6	-172.5	177.1	178.3	-178.3	0	114.1
500	F	83.2	Confident	89.7	Confident	200 Å²	200	95.3 Å²	95.3	88%	0.877	48%	0.48	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.1	-14.3	-178.6	-56	-76	0	0	0	114.7	N498	N498-F500 PolarHBondContact O-N 2.76Å
501	T	85	Confident	89.7	Confident	88 Å²	88	94.7 Å²	94.7	54%	0.54	48%	0.484	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.4	-3	-175.1	53.5	0	0	0	0	113.8	Y493 N498	Y493-T501 PolarHBondContact OH-O 2.89Å; N498-T501 PolarHBondContact N-OG1 3.49Å; N498-T501 PolarHBondContact O-N 2.72Å; N498-T501 PolarHBondContact O-OG1 2.89Å; N498-T501 VanDerWaalsContact O-OG1 3.07Å
502	R	85.3	Confident	89.8	Confident	97 Å²	97	94.7 Å²	94.7	37%	0.366	49%	0.489	S	S	.	.			trans	-81.7	132.2	-176.4	-76.1	-179.8	63.4	150.7	2.1	111.7	E494 N498 E507	E494-R502 IonicContact OE1-CZ 3.51Å; E494-R502 IonicContact OE1-NH2 2.8Å; E494-R502 PolarHBondContact OE1-NH2 3.35Å; E494-R502 IonicContact OE2-CZ 3.03Å; E494-R502 IonicContact OE2-NH1 2.74Å; E494-R502 PolarHBondContact OE2-NH1 2.86Å; E494-R502 IonicContact OE2-NH2 2.78Å; E494-R502 PolarHBondContact OE2-NH2 2.04Å; N498-R502 PolarHBondContact O-N 3.3Å; R502-E507 WeakPolarHBondContact CB-OE1 3.42Å; R502-E507 IonicContact CZ-OE1 3.39Å; R502-E507 IonicContact CZ-OE2 3.9Å; R502-E507 IonicContact NE-OE1 2.82Å; R502-E507 PolarHBondContact NE-OE1 2.66Å; R502-E507 IonicContact NE-OE2 3.96Å; R502-E507 VanDerWaalsContact NH2-CD 3.32Å; R502-E507 IonicContact NH2-OE1 3.19Å; R502-E507 PolarHBondContact NH2-OE1 2.97Å; R502-E507 IonicContact NH2-OE2 2.98Å; R502-E507 PolarHBondContact NH2-OE2 3.42Å
503	N	88.5	Confident	89.8	Confident	108 Å²	108	92.2 Å²	92.2	58%	0.578	48%	0.475	S	S	*	.			trans	-120.9	110.6	177.2	-98.2	-41.8	0	0	0	109.8	Y493 L505 K506 E507	Y493-N503 PolarHBondContact OH-N 3.48Å; N503-L505 PolarHBondContact O-N 2.7Å; N503-K506 HydrophobicContact CB-CB 4.1Å; N503-K506 WeakPolarHBondContact O-CB 3.14Å; N503-K506 PolarHBondContact O-N 3.16Å; N503-E507 PolarHBondContact O-N 3.05Å; N503-E507 VanDerWaalsContact O-N 3.08Å
504	L	90.4	Very high	90	Very high	124 Å²	124	91 Å²	91	65%	0.649	47%	0.471	S	S	*	.	H	α-helix	trans	-54.9	-38.9	-177.4	-170.8	73	0	0	0	112.5	K506 E507 M508	L504-K506 VanDerWaalsContact C-N 3.32Å; L504-K506 PolarHBondContact O-N 3.49Å; L504-E507 PolarHBondContact O-N 3.5Å; L504-M508 WeakPolarHBondContact O-CB 3.47Å; L504-M508 WeakPolarHBondContact O-CG 3.37Å; L504-M508 PolarHBondContact O-N 3.28Å
505	L	90	Very high	90.3	Very high	129 Å²	129	92.8 Å²	92.8	68%	0.675	49%	0.489	S	S	*	.	H	α-helix	trans	-61.2	-40.9	177.4	-176.1	67.9	0	0	0	111.9	N503 I509	N503-L505 PolarHBondContact O-N 2.7Å; L505-I509 HydrophobicContact CD1-CD1 4.22Å; L505-I509 HydrophobicContact CG-CD1 3.96Å; L505-I509 WeakPolarHBondContact O-CB 3.43Å; L505-I509 VanDerWaalsContact O-CG1 3.23Å; L505-I509 WeakPolarHBondContact O-CG1 3.03Å; L505-I509 PolarHBondContact O-N 3.19Å
506	K	91.2	Very high	90.4	Very high	99 Å²	99	89.2 Å²	89.2	43%	0.43	47%	0.473	S	S	.	.	H	α-helix	trans	-68.7	-41.2	178.4	-175	179.6	177.4	-178.1	0	110.9	Y493 N503 L504 I509 L510	Y493-K506 HydrophobicContact CE2-CD 4.05Å; N503-K506 HydrophobicContact CB-CB 4.1Å; N503-K506 WeakPolarHBondContact O-CB 3.14Å; N503-K506 PolarHBondContact O-N 3.16Å; L504-K506 VanDerWaalsContact C-N 3.32Å; L504-K506 PolarHBondContact O-N 3.49Å; K506-I509 PolarHBondContact O-N 2.88Å; K506-L510 VanDerWaalsContact O-CB 3.27Å; K506-L510 WeakPolarHBondContact O-CB 3.47Å; K506-L510 PolarHBondContact O-N 3.42Å
507	E	92.5	Very high	90.7	Very high	21 Å²	21	87.5 Å²	87.5	10%	0.098	46%	0.456	C	S	.	.	H	α-helix	trans	-60.3	-48.4	175.7	-67.5	173	-162.6	0	0	110.9	F490 Y493 E494 R502 N503 L504 L510 A511	F490-E507 HydrophobicContact CE2-CB 4.27Å; Y493-E507 HydrophobicContact CD1-CG 3.97Å; Y493-E507 HydrophobicContact CE1-CG 3.59Å; E494-E507 VanDerWaalsContact OE1-CD 3.28Å; R502-E507 WeakPolarHBondContact CB-OE1 3.42Å; R502-E507 IonicContact CZ-OE1 3.39Å; R502-E507 IonicContact CZ-OE2 3.9Å; R502-E507 IonicContact NE-OE1 2.82Å; R502-E507 PolarHBondContact NE-OE1 2.66Å; R502-E507 IonicContact NE-OE2 3.96Å; R502-E507 VanDerWaalsContact NH2-CD 3.32Å; R502-E507 IonicContact NH2-OE1 3.19Å; R502-E507 PolarHBondContact NH2-OE1 2.97Å; R502-E507 IonicContact NH2-OE2 2.98Å; R502-E507 PolarHBondContact NH2-OE2 3.42Å; N503-E507 PolarHBondContact O-N 3.05Å; N503-E507 VanDerWaalsContact O-N 3.08Å; L504-E507 PolarHBondContact O-N 3.5Å; E507-L510 PolarHBondContact O-N 2.02Å; E507-A511 VanDerWaalsContact O-CB 3.26Å; E507-A511 WeakPolarHBondContact O-CB 3.39Å; E507-A511 PolarHBondContact O-N 2.72Å
508	M	93.3	Very high	91.3	Very high	123 Å²	123	88.8 Å²	88.8	61%	0.606	46%	0.461	S	S	*	.	H	α-helix	trans	-61.9	-45.6	177.9	-75.6	-172.3	67.8	0	0	112.6	L504 L512	L504-M508 WeakPolarHBondContact O-CB 3.47Å; L504-M508 WeakPolarHBondContact O-CG 3.37Å; L504-M508 PolarHBondContact O-N 3.28Å; M508-L512 WeakPolarHBondContact O-CB 2.97Å; M508-L512 PolarHBondContact O-N 3.1Å
509	I	93.5	Very high	91.7	Very high	97 Å²	97	85.4 Å²	85.4	50%	0.497	45%	0.453	S	S	.	.	H	α-helix	trans	-62.5	-45.8	178.9	-70.4	167.7	0	0	0	110.2	L505 K506 L512 V513	L505-I509 HydrophobicContact CD1-CD1 4.22Å; L505-I509 HydrophobicContact CG-CD1 3.96Å; L505-I509 WeakPolarHBondContact O-CB 3.43Å; L505-I509 VanDerWaalsContact O-CG1 3.23Å; L505-I509 WeakPolarHBondContact O-CG1 3.03Å; L505-I509 PolarHBondContact O-N 3.19Å; K506-I509 PolarHBondContact O-N 2.88Å; I509-L512 PolarHBondContact O-N 3.23Å; I509-V513 HydrophobicContact CG2-CG2 4.45Å; I509-V513 VanDerWaalsContact O-CG2 3.28Å; I509-V513 WeakPolarHBondContact O-CG2 3.39Å; I509-V513 PolarHBondContact O-N 3.44Å
510	L	92.3	Very high	92.1	Very high	18 Å²	18	79.8 Å²	79.8	9%	0.094	44%	0.435	C	S	.	.	H	α-helix	trans	-66.2	-43.6	-177.8	-166	72.9	0	0	0	111.8	F486 W489 F490 K506 E507 V513 A514	F486-L510 HydrophobicContact CD1-CD1 3.6Å; F486-L510 HydrophobicContact CE1-CD1 4.21Å; W489-L510 HydrophobicContact CB-CD2 4.33Å; W489-L510 VanDerWaalsContact CD1-CD2 3.44Å; W489-L510 HydrophobicContact CG-CD1 4.3Å; W489-L510 HydrophobicContact CG-CD2 4.13Å; F490-L510 HydrophobicContact CB-CD2 3.7Å; F490-L510 HydrophobicContact CB-CG 4.11Å; F490-L510 HydrophobicContact CD2-CB 4.38Å; F490-L510 HydrophobicContact CD2-CD2 4.12Å; F490-L510 HydrophobicContact CD2-CG 4.47Å; F490-L510 HydrophobicContact CG-CD2 4.42Å; K506-L510 VanDerWaalsContact O-CB 3.27Å; K506-L510 WeakPolarHBondContact O-CB 3.47Å; K506-L510 PolarHBondContact O-N 3.42Å; E507-L510 PolarHBondContact O-N 2.02Å; L510-V513 PolarHBondContact O-N 2.98Å; L510-A514 WeakPolarHBondContact O-CB 2.86Å; L510-A514 PolarHBondContact O-N 3.22Å
511	A	93.7	Very high	92.7	Very high	36 Å²	36	70.2 Å²	70.2	30%	0.298	39%	0.393	S	S	.	.	H	α-helix	trans	-63.6	-40.7	175.9	0	0	0	0	0	112	F490 E507 A514 S515	F490-A511 HydrophobicContact CD2-CB 4.16Å; F490-A511 HydrophobicContact CE2-CB 3.96Å; F490-A511 HydrophobicContact CZ-CB 4.48Å; E507-A511 VanDerWaalsContact O-CB 3.26Å; E507-A511 WeakPolarHBondContact O-CB 3.39Å; E507-A511 PolarHBondContact O-N 2.72Å; A511-A514 PolarHBondContact O-N 2.93Å; A511-S515 VanDerWaalsContact O-CB 3.28Å; A511-S515 WeakPolarHBondContact O-CB 3.21Å; A511-S515 PolarHBondContact O-N 3.09Å
512	L	94.7	Very high	93.1	Very high	127 Å²	127	68.2 Å²	68.2	67%	0.665	38%	0.382	S	S	*	.	H	α-helix	trans	-66.3	-44.3	178.4	-175	140.1	0	0	0	111.8	M508 I509 S515 A516	M508-L512 WeakPolarHBondContact O-CB 2.97Å; M508-L512 PolarHBondContact O-N 3.1Å; I509-L512 PolarHBondContact O-N 3.23Å; L512-S515 PolarHBondContact O-N 3.02Å; L512-A516 WeakPolarHBondContact O-CB 2.97Å; L512-A516 PolarHBondContact O-N 3.18Å
513	V	94.9	Very high	93.5	Very high	39 Å²	39	67.8 Å²	67.8	24%	0.236	39%	0.387	C	S	.	.	H	α-helix	trans	-62.7	-48.2	175.4	173.5	0	0	0	0	110.3	F486 I509 L510 S515 A516 F517	F486-V513 HydrophobicContact CD1-CG1 4.23Å; F486-V513 HydrophobicContact CD2-CG1 3.74Å; F486-V513 HydrophobicContact CE1-CG1 4.29Å; F486-V513 HydrophobicContact CE2-CG1 3.82Å; F486-V513 HydrophobicContact CG-CG1 3.96Å; F486-V513 HydrophobicContact CZ-CG1 4.1Å; I509-V513 HydrophobicContact CG2-CG2 4.45Å; I509-V513 VanDerWaalsContact O-CG2 3.28Å; I509-V513 WeakPolarHBondContact O-CG2 3.39Å; I509-V513 PolarHBondContact O-N 3.44Å; L510-V513 PolarHBondContact O-N 2.98Å; V513-S515 PolarHBondContact O-N 3.19Å; V513-A516 PolarHBondContact O-N 3.28Å; V513-F517 HydrophobicContact CG1-CD2 3.86Å; V513-F517 HydrophobicContact CG1-CE2 3.97Å; V513-F517 WeakPolarHBondContact O-CD2 2.95Å; V513-F517 PolarHBondContact O-N 3.07Å; V513-F517 VanDerWaalsContact O-N 3.15Å
514	A	95	Very high	93.7	Very high	6 Å²	6	63.4 Å²	63.4	5%	0.05	36%	0.363	C	S	.	.	H	α-helix	trans	-56.9	-49.9	176.9	0	0	0	0	0	111.9	F486 L510 A511 A516 F517 V518	F486-A514 HydrophobicContact CB-CB 3.85Å; L510-A514 WeakPolarHBondContact O-CB 2.86Å; L510-A514 PolarHBondContact O-N 3.22Å; A511-A514 PolarHBondContact O-N 2.93Å; A514-A516 VanDerWaalsContact C-N 3.34Å; A514-A516 PolarHBondContact O-N 3.43Å; A514-F517 PolarHBondContact O-N 2.9Å; A514-V518 WeakPolarHBondContact O-CB 3.42Å; A514-V518 VanDerWaalsContact O-CG2 3.29Å; A514-V518 WeakPolarHBondContact O-CG2 2.98Å; A514-V518 PolarHBondContact O-N 3.2Å
515	S	96.4	Very high	93.8	Very high	86 Å²	86	60.7 Å²	60.7	60%	0.601	35%	0.348	S	S	*	.	H	α-helix	trans	-61.8	-39	-179.6	-174.6	0	0	0	0	112.7	A511 L512 V513 G519	A511-S515 VanDerWaalsContact O-CB 3.28Å; A511-S515 WeakPolarHBondContact O-CB 3.21Å; A511-S515 PolarHBondContact O-N 3.09Å; L512-S515 PolarHBondContact O-N 3.02Å; V513-S515 PolarHBondContact O-N 3.19Å; S515-G519 PolarHBondContact O-N 3.14Å
516	A	95.3	Very high	93.9	Very high	52 Å²	52	58.1 Å²	58.1	43%	0.43	34%	0.335	S	S	.	.	H	α-helix	trans	-65.9	-49.3	179.3	0	0	0	0	0	111.5	L512 V513 A514 G519 V520	L512-A516 WeakPolarHBondContact O-CB 2.97Å; L512-A516 PolarHBondContact O-N 3.18Å; V513-A516 PolarHBondContact O-N 3.28Å; A514-A516 VanDerWaalsContact C-N 3.34Å; A514-A516 PolarHBondContact O-N 3.43Å; A516-G519 PolarHBondContact O-N 2.8Å; A516-V520 WeakPolarHBondContact O-CG2 3.24Å; A516-V520 PolarHBondContact O-N 2.83Å
517	F	96.2	Very high	93.9	Very high	67 Å²	67	54.7 Å²	54.7	29%	0.294	32%	0.321	S	S	.	.	H	α-helix	trans	-67.5	-41.4	-179.4	-83.4	-83.4	0	0	0	112.5	L479 I482 V513 A514 G521	L479-F517 HydrophobicContact CD2-CD1 3.55Å; L479-F517 HydrophobicContact CD2-CE1 3.68Å; I482-F517 HydrophobicContact CB-CD1 4.01Å; I482-F517 HydrophobicContact CB-CE1 4.39Å; I482-F517 HydrophobicContact CB-CG 4.41Å; I482-F517 HydrophobicContact CD1-CD1 4.49Å; I482-F517 HydrophobicContact CD1-CE1 4.18Å; I482-F517 HydrophobicContact CG2-CB 4.48Å; I482-F517 HydrophobicContact CG2-CD1 3.69Å; I482-F517 HydrophobicContact CG2-CD2 4.11Å; I482-F517 HydrophobicContact CG2-CE1 3.86Å; I482-F517 HydrophobicContact CG2-CE2 4.27Å; I482-F517 HydrophobicContact CG2-CG 3.83Å; I482-F517 HydrophobicContact CG2-CZ 4.15Å; V513-F517 HydrophobicContact CG1-CD2 3.86Å; V513-F517 HydrophobicContact CG1-CE2 3.97Å; V513-F517 WeakPolarHBondContact O-CD2 2.95Å; V513-F517 PolarHBondContact O-N 3.07Å; V513-F517 VanDerWaalsContact O-N 3.15Å; A514-F517 PolarHBondContact O-N 2.9Å; F517-G521 PolarHBondContact O-N 3.35Å
518	V	95.5	Very high	93.8	Very high	43 Å²	43	60 Å²	60	26%	0.261	34%	0.34	S	S	.	.	H	α-helix	trans	-64.6	-46.1	175.4	174.4	0	0	0	0	110.6	A514 G521 S522	A514-V518 WeakPolarHBondContact O-CB 3.42Å; A514-V518 VanDerWaalsContact O-CG2 3.29Å; A514-V518 WeakPolarHBondContact O-CG2 2.98Å; A514-V518 PolarHBondContact O-N 3.2Å; V518-G521 PolarHBondContact O-N 3.21Å; V518-S522 WeakPolarHBondContact O-CB 3.42Å; V518-S522 PolarHBondContact O-N 3.17Å; V518-S522 PolarHBondContact O-OG 3.21Å
519	G	94.6	Very high	93.8	Very high	43 Å²	43	59 Å²	59	44%	0.443	34%	0.341	S	S	.	.	H	α-helix	trans	-60.2	-50.4	-179.8	0	0	0	0	0	113.2	S515 A516 S522 L523	S515-G519 PolarHBondContact O-N 3.14Å; A516-G519 PolarHBondContact O-N 2.8Å; G519-S522 PolarHBondContact O-N 3.45Å; G519-L523 PolarHBondContact O-N 2.73Å; G519-L523 VanDerWaalsContact O-N 3.11Å
520	V	92.8	Very high	93.4	Very high	72 Å²	72	56.4 Å²	56.4	44%	0.436	34%	0.338	S	S	.	.	H	α-helix	trans	-67.3	-41	178.2	-177.9	0	0	0	0	110.9	L479 A516 S522 L523 F524	L479-V520 HydrophobicContact CD1-CB 4.33Å; L479-V520 HydrophobicContact CD1-CG1 3.71Å; A516-V520 WeakPolarHBondContact O-CG2 3.24Å; A516-V520 PolarHBondContact O-N 2.83Å; V520-S522 VanDerWaalsContact C-N 3.35Å; V520-S522 PolarHBondContact O-N 2.69Å; V520-L523 WeakPolarHBondContact O-CB 3.32Å; V520-L523 PolarHBondContact O-N 3.13Å; V520-F524 HydrophobicContact CG1-CD2 3.9Å; V520-F524 HydrophobicContact CG1-CE2 3.63Å; V520-F524 VanDerWaalsContact O-CD2 3.26Å; V520-F524 WeakPolarHBondContact O-CD2 3.18Å; V520-F524 PolarHBondContact O-N 3.39Å; V520-F524 VanDerWaalsContact O-N 3.12Å
521	G	95	Very high	93.3	Very high	0 Å²	0	60 Å²	60	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-60.9	-40	176.5	0	0	0	0	0	113.4	S476 F517 V518 F524 L525	S476-G521 PolarHBondContact OG-O 3.08Å; F517-G521 PolarHBondContact O-N 3.35Å; V518-G521 PolarHBondContact O-N 3.21Å; G521-F524 PolarHBondContact O-N 3.46Å; G521-L525 PolarHBondContact O-N 3.17Å
522	S	93.9	Very high	92.9	Very high	46 Å²	46	66 Å²	66	32%	0.322	37%	0.373	S	S	.	.	H	α-helix	trans	-67.1	-36.4	174.7	-66.9	0	0	0	0	112.6	V518 G519 V520 L525 L526	V518-S522 WeakPolarHBondContact O-CB 3.42Å; V518-S522 PolarHBondContact O-N 3.17Å; V518-S522 PolarHBondContact O-OG 3.21Å; G519-S522 PolarHBondContact O-N 3.45Å; V520-S522 VanDerWaalsContact C-N 3.35Å; V520-S522 PolarHBondContact O-N 2.69Å; S522-L525 WeakPolarHBondContact O-CB 3.31Å; S522-L525 PolarHBondContact O-N 2.84Å; S522-L526 WeakPolarHBondContact O-CG 3.31Å; S522-L526 PolarHBondContact O-N 2.98Å
523	L	92.7	Very high	92	Very high	87 Å²	87	67.8 Å²	67.8	46%	0.455	39%	0.388	S	S	.	.	H	α-helix	trans	-62.2	-45.7	173.8	-178.9	145.6	0	0	0	111.3	G519 V520 L525 L526 L527	G519-L523 PolarHBondContact O-N 2.73Å; G519-L523 VanDerWaalsContact O-N 3.11Å; V520-L523 WeakPolarHBondContact O-CB 3.32Å; V520-L523 PolarHBondContact O-N 3.13Å; L523-L525 VanDerWaalsContact C-N 3.27Å; L523-L525 PolarHBondContact O-N 3.38Å; L523-L526 PolarHBondContact O-N 3.42Å; L523-L527 HydrophobicContact CD2-CD1 3.64Å; L523-L527 HydrophobicContact CD2-CG 4.4Å; L523-L527 WeakPolarHBondContact O-CG 3.42Å; L523-L527 PolarHBondContact O-N 3.1Å
524	F	92.7	Very high	91.9	Very high	17 Å²	17	69.3 Å²	69.3	8%	0.075	40%	0.396	C	S	.	.	H	α-helix	trans	-66.4	-29.2	174.5	-76.9	-73.4	0	0	0	113.1	I467 Y472 L475 L479 V520 G521 L527 W528	I467-F524 HydrophobicContact CD1-CE1 3.81Å; I467-F524 HydrophobicContact CD1-CZ 3.45Å; I467-F524 VanDerWaalsContact CD1-CZ 3.45Å; I467-F524 HydrophobicContact CG2-CE1 4.34Å; Y472-F524 AromaticContact CD1-CD1 3.86Å; Y472-F524 HydrophobicContact CD1-CD1 3.86Å; Y472-F524 AromaticContact CD1-CE1 3.99Å; Y472-F524 HydrophobicContact CD1-CE1 3.99Å; Y472-F524 HydrophobicContact CE1-CD1 4.38Å; Y472-F524 HydrophobicContact CE1-CE1 4.15Å; Y472-F524 HydrophobicContact CG-CD1 4.38Å; L475-F524 HydrophobicContact CB-CG 4.42Å; L475-F524 HydrophobicContact CD2-CD1 4.18Å; L475-F524 HydrophobicContact CD2-CD2 3.58Å; L475-F524 HydrophobicContact CD2-CE1 3.9Å; L475-F524 HydrophobicContact CD2-CE2 3.26Å; L475-F524 HydrophobicContact CD2-CG 4.04Å; L475-F524 HydrophobicContact CD2-CZ 3.45Å; L475-F524 VanDerWaalsContact CD2-CZ 3.45Å; L479-F524 HydrophobicContact CD1-CD2 3.93Å; L479-F524 HydrophobicContact CD1-CE2 4.24Å; V520-F524 HydrophobicContact CG1-CD2 3.9Å; V520-F524 HydrophobicContact CG1-CE2 3.63Å; V520-F524 VanDerWaalsContact O-CD2 3.26Å; V520-F524 WeakPolarHBondContact O-CD2 3.18Å; V520-F524 PolarHBondContact O-N 3.39Å; V520-F524 VanDerWaalsContact O-N 3.12Å; G521-F524 PolarHBondContact O-N 3.46Å; F524-L527 HydrophobicContact CD1-CD1 4.26Å; F524-L527 HydrophobicContact CE1-CD1 4.47Å; F524-W528 VanDerWaalsContact O-CB 3.29Å; F524-W528 WeakPolarHBondContact O-CB 3.42Å; F524-W528 PolarHBondContact O-N 3.01Å
525	L	93.3	Very high	91.7	Very high	66 Å²	66	72.6 Å²	72.6	35%	0.346	41%	0.414	S	S	.	.	H	α-helix	trans	-66.3	-45.7	173.5	-173.5	65.3	0	0	0	111.1	S476 L480 G521 S522 L523 W528 V529	S476-L525 VanDerWaalsContact OG-CA 3.31Å; S476-L525 WeakPolarHBondContact OG-CA 3.32Å; S476-L525 WeakPolarHBondContact OG-CB 3.33Å; S476-L525 PolarHBondContact OG-N 3.37Å; L480-L525 HydrophobicContact CD1-CB 4.28Å; L480-L525 HydrophobicContact CD1-CD2 4.07Å; G521-L525 PolarHBondContact O-N 3.17Å; S522-L525 WeakPolarHBondContact O-CB 3.31Å; S522-L525 PolarHBondContact O-N 2.84Å; L523-L525 VanDerWaalsContact C-N 3.27Å; L523-L525 PolarHBondContact O-N 3.38Å; L525-W528 HydrophobicContact CD1-CE3 3.88Å; L525-W528 HydrophobicContact CD1-CZ3 4.27Å; L525-W528 PolarHBondContact O-N 3.22Å; L525-V529 VanDerWaalsContact O-CG2 3.32Å; L525-V529 WeakPolarHBondContact O-CG2 3.23Å; L525-V529 PolarHBondContact O-N 2.95Å
526	L	92.5	Very high	91.4	Very high	76 Å²	76	71.8 Å²	71.8	40%	0.398	40%	0.404	S	S	.	.	H	α-helix	trans	-62	-44	176.5	-71.4	173.5	0	0	0	111.7	S522 L523 W528 V529 G530 I531 V533	S522-L526 WeakPolarHBondContact O-CG 3.31Å; S522-L526 PolarHBondContact O-N 2.98Å; L523-L526 PolarHBondContact O-N 3.42Å; L526-W528 VanDerWaalsContact C-N 3.29Å; L526-W528 PolarHBondContact O-N 3.45Å; L526-V529 PolarHBondContact O-N 3.22Å; L526-G530 PolarHBondContact O-N 3.39Å; L526-I531 CarbonylContact C-O 3.41Å; L526-I531 HydrophobicContact CD2-CD1 4.23Å; L526-I531 PolarHBondContact O-N 3.44Å; L526-V533 HydrophobicContact CD1-CG2 4.33Å
527	L	90.2	Very high	91.2	Very high	27 Å²	27	73 Å²	73	14%	0.141	40%	0.402	C	S	.	.	H	α-helix	trans	-60.4	-38.6	173.7	-72.5	174.3	0	0	0	112.1	Y472 L523 F524 G530 Y532	Y472-L527 HydrophobicContact CD2-CB 4.11Å; Y472-L527 HydrophobicContact CE2-CB 4.2Å; L523-L527 HydrophobicContact CD2-CD1 3.64Å; L523-L527 HydrophobicContact CD2-CG 4.4Å; L523-L527 WeakPolarHBondContact O-CG 3.42Å; L523-L527 PolarHBondContact O-N 3.1Å; F524-L527 HydrophobicContact CD1-CD1 4.26Å; F524-L527 HydrophobicContact CE1-CD1 4.47Å; L527-G530 PolarHBondContact O-N 2.84Å; L527-Y532 HydrophobicContact CD2-CD1 3.78Å; L527-Y532 HydrophobicContact CD2-CE1 4.4Å; L527-Y532 HydrophobicContact CD2-CG 4.46Å
528	W	91.5	Very high	90.9	Very high	131 Å²	131	73.4 Å²	73.4	50%	0.496	41%	0.409	S	S	.	.	H	α-helix	trans	-69.2	-37.1	176.9	179.2	23.8	0	0	0	112.4	P473 V477 F524 L525 L526 G530	P473-W528 HydrophobicContact CB-CD2 3.89Å; P473-W528 HydrophobicContact CB-CE3 4.2Å; P473-W528 HydrophobicContact CB-CG 4.41Å; P473-W528 HydrophobicContact CB-CH2 4.23Å; P473-W528 HydrophobicContact CB-CZ2 3.91Å; P473-W528 HydrophobicContact CB-CZ3 4.37Å; P473-W528 HydrophobicContact CG-CD2 4.1Å; P473-W528 HydrophobicContact CG-CG 4.14Å; P473-W528 HydrophobicContact CG-CZ2 4.4Å; V477-W528 HydrophobicContact CG2-CZ3 4.32Å; F524-W528 VanDerWaalsContact O-CB 3.29Å; F524-W528 WeakPolarHBondContact O-CB 3.42Å; F524-W528 PolarHBondContact O-N 3.01Å; L525-W528 HydrophobicContact CD1-CE3 3.88Å; L525-W528 HydrophobicContact CD1-CZ3 4.27Å; L525-W528 PolarHBondContact O-N 3.22Å; L526-W528 VanDerWaalsContact C-N 3.29Å; L526-W528 PolarHBondContact O-N 3.45Å; W528-G530 PolarHBondContact O-N 2.65Å
529	V	92	Very high	90.6	Very high	104 Å²	104	75.4 Å²	75.4	63%	0.63	42%	0.419	S	S	*	.	H	α-helix	trans	-67.7	-11.6	174.3	175.6	0	0	0	0	112.2	L525 L526 I531	L525-V529 VanDerWaalsContact O-CG2 3.32Å; L525-V529 WeakPolarHBondContact O-CG2 3.23Å; L525-V529 PolarHBondContact O-N 2.95Å; L526-V529 PolarHBondContact O-N 3.22Å; V529-I531 HydrophobicContact CG1-CD1 4.44Å; V529-I531 HydrophobicContact CG1-CG1 4.44Å
530	G	86.4	Confident	90.3	Very high	41 Å²	41	77.7 Å²	77.7	42%	0.423	42%	0.417	S	S	.	.	T	Hydrogen-bonded Turn	trans	92.5	11.4	180	0	0	0	0	0	113.7	L526 L527 W528 Y532	L526-G530 PolarHBondContact O-N 3.39Å; L527-G530 PolarHBondContact O-N 2.84Å; W528-G530 PolarHBondContact O-N 2.65Å; G530-Y532 WeakPolarHBondContact O-CD2 3.23Å; G530-Y532 PolarHBondContact O-N 3.2Å
531	I	89	Confident	90.1	Very high	94 Å²	94	78.2 Å²	78.2	48%	0.482	42%	0.415	S	S	.	.			trans	-89.4	94.7	170.6	-55.9	176.5	0	0	0	107.1	L526 V529 V533	L526-I531 CarbonylContact C-O 3.41Å; L526-I531 HydrophobicContact CD2-CD1 4.23Å; L526-I531 PolarHBondContact O-N 3.44Å; V529-I531 HydrophobicContact CG1-CD1 4.44Å; V529-I531 HydrophobicContact CG1-CG1 4.44Å; I531-V533 HydrophobicContact CG2-CG2 4.24Å; I531-V533 PolarHBondContact O-N 2.91Å
532	Y	85.1	Confident	89.7	Confident	163 Å²	163	84.7 Å²	84.7	64%	0.639	45%	0.45	S	S	*	.			trans	-80.7	96.2	175.3	-64	-87.1	0	0	0	109.5	L527 G530	L527-Y532 HydrophobicContact CD2-CD1 3.78Å; L527-Y532 HydrophobicContact CD2-CE1 4.4Å; L527-Y532 HydrophobicContact CD2-CG 4.46Å; G530-Y532 WeakPolarHBondContact O-CD2 3.23Å; G530-Y532 PolarHBondContact O-N 3.2Å
533	V	77.2	Confident	89.3	Confident	164 Å²	164	88.2 Å²	88.2	99%	0.994	46%	0.462	S	S	*	.			trans	-71.6	0	177.4	-176.4	0	0	0	0	111.6	L526 I531	L526-V533 HydrophobicContact CD1-CG2 4.33Å; I531-V533 HydrophobicContact CG2-CG2 4.24Å; I531-V533 PolarHBondContact O-N 2.91Å

Retrieved 533 of 533 residues in 103.9 ms (Link to these results)

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