A0A077ZBR6_TRITR Loading...

formate C-acetyltransferase

AlphaFold DB , UniProt , Accession A0A077ZBR6, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 763 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39.4Very low45.6Very low215 Ų215103 Ų103100%1.05958%0.58SS**  0-29.30-73.1-174.4-165.700113.5T5M1-T5 PolarHBondContact O-OG1 3.18Å
2G39.2Very low46.8Very low63 Ų63103.8 Ų103.865%0.64957%0.572SS**Hα-helixtrans-76.8-23.2178.900000116.7T5G2-T5 PolarHBondContact O-OG1 3.35Å
3T43.5Very low47.7Very low108 Ų108103.8 Ų103.866%0.66357%0.571SS**Hα-helixtrans-82.4-42.6179.443.80000113T5 N6 E7T3-T5 VanDerWaalsContact C-N 3.31Å; T3-T5 PolarHBondContact O-N 3.29Å; T3-N6 PolarHBondContact O-N 3.08Å; T3-E7 PolarHBondContact O-N 3.17Å
4A41.1Very low48.6Very low52 Ų5299.8 Ų99.843%0.4355%0.551SS.*Hα-helixtrans-62.8-32.2-179.300000114L8A4-L8 WeakPolarHBondContact O-CB 3.48Å; A4-L8 WeakPolarHBondContact O-CD1 3.48Å; A4-L8 PolarHBondContact O-N 3.3Å
5T43.1Very low49.7Very low84 Ų8495.5 Ų95.552%0.51553%0.525SS..Hα-helixtrans-70.1-34.5176.527.30000113.2M1 G2 T3 D9M1-T5 PolarHBondContact O-OG1 3.18Å; G2-T5 PolarHBondContact O-OG1 3.35Å; T3-T5 VanDerWaalsContact C-N 3.31Å; T3-T5 PolarHBondContact O-N 3.29Å; T5-D9 PolarHBondContact O-N 3.48Å; T5-D9 VanDerWaalsContact O-N 3.15Å
6N47.7Very low50.8Low114 Ų11498.8 Ų98.861%0.6153%0.533SS*.Hα-helixtrans-74.2-35.7-180-120.66.9000111.6T3 Q10T3-N6 PolarHBondContact O-N 3.08Å; N6-Q10 PolarHBondContact O-N 3.2Å; N6-Q10 VanDerWaalsContact O-N 3.08Å
7E49.1Very low52.7Low121 Ų12197.6 Ų97.657%0.56553%0.53SS*.Hα-helixtrans-66.2-42.3173.6-71.8172.4172.100111.4T3 D9 Q10 M11T3-E7 PolarHBondContact O-N 3.17Å; E7-D9 PolarHBondContact O-N 3.18Å; E7-Q10 PolarHBondContact O-N 3.15Å; E7-M11 WeakPolarHBondContact O-CG 3.4Å; E7-M11 PolarHBondContact O-N 3.35Å
8L44.3Very low54.9Low97 Ų9792.2 Ų92.251%0.50850%0.501SS..Hα-helixtrans-62.8-40.3175.9-87.6159.8000113.4A4 K12A4-L8 WeakPolarHBondContact O-CB 3.48Å; A4-L8 WeakPolarHBondContact O-CD1 3.48Å; A4-L8 PolarHBondContact O-N 3.3Å; L8-K12 WeakPolarHBondContact O-CG 3.5Å; L8-K12 PolarHBondContact O-N 3.01Å
9D48.8Very low57Low95 Ų9588.4 Ų88.451%0.50848%0.478SS..Hα-helixtrans-73.7-31.5178-82.5-16.3000112.5T5 E7 N13T5-D9 PolarHBondContact O-N 3.48Å; T5-D9 VanDerWaalsContact O-N 3.15Å; E7-D9 PolarHBondContact O-N 3.18Å; D9-N13 PolarHBondContact O-N 3.1Å
10Q52.3Low58.7Low133 Ų13390.2 Ų90.262%0.62148%0.483SS*.Hα-helixtrans-67.9-45.7170.8-80.3-175.2-14.900112N6 E7 K12 N13 T14N6-Q10 PolarHBondContact O-N 3.2Å; N6-Q10 VanDerWaalsContact O-N 3.08Å; E7-Q10 PolarHBondContact O-N 3.15Å; Q10-K12 VanDerWaalsContact C-N 3.28Å; Q10-K12 PolarHBondContact O-N 3.42Å; Q10-N13 PolarHBondContact O-N 3.11Å; Q10-T14 PolarHBondContact O-N 3.31Å; Q10-T14 VanDerWaalsContact O-N 3.11Å; Q10-T14 PolarHBondContact O-OG1 2.92Å; Q10-T14 VanDerWaalsContact O-OG1 3.1Å
11M53.5Low60.3Low51 Ų5189 Ų8925%0.25149%0.493SS..Hα-helixtrans-54.1-45.4175.2-75.6179.473.700111.3E7 N13 T14 E15 D201E7-M11 WeakPolarHBondContact O-CG 3.4Å; E7-M11 PolarHBondContact O-N 3.35Å; M11-N13 PolarHBondContact O-N 3.49Å; M11-T14 PolarHBondContact O-N 2.62Å; M11-E15 WeakPolarHBondContact O-CB 3.49Å; M11-E15 VanDerWaalsContact O-CG 3.27Å; M11-E15 WeakPolarHBondContact O-CG 3.37Å; M11-E15 PolarHBondContact O-N 2.72Å; M11-D201 HydrophobicContact CE-CB 4.46Å
12K59Low63Low112 Ų11279.4 Ų79.449%0.48745%0.445SS..Hα-helixtrans-61.2-26.8177.6-77.5176.7-177.7171.20114.6L8 Q10 K16L8-K12 WeakPolarHBondContact O-CG 3.5Å; L8-K12 PolarHBondContact O-N 3.01Å; Q10-K12 VanDerWaalsContact C-N 3.28Å; Q10-K12 PolarHBondContact O-N 3.42Å; K12-K16 WeakPolarHBondContact O-CD 3.21Å; K12-K16 VanDerWaalsContact O-CG 3.26Å; K12-K16 WeakPolarHBondContact O-CG 3.48Å; K12-K16 PolarHBondContact O-N 3.21Å
13N58.9Low65.8Low104 Ų10481.4 Ų81.456%0.55644%0.441SS*.Hα-helixtrans-83.7-37.9177-93.9-7.8000112.1D9 Q10 M11 K16 T17D9-N13 PolarHBondContact O-N 3.1Å; Q10-N13 PolarHBondContact O-N 3.11Å; M11-N13 PolarHBondContact O-N 3.49Å; N13-K16 PolarHBondContact O-N 2.88Å; N13-T17 PolarHBondContact O-N 2.66Å; N13-T17 PolarHBondContact O-OG1 3.35Å
14T59.8Low68.2Low48 Ų4877.7 Ų77.729%0.29442%0.424SS..Hα-helixtrans-68.3-40.2175.8-38.70000111.3Q10 M11 K16 T17 A18 R253Q10-T14 PolarHBondContact O-N 3.31Å; Q10-T14 VanDerWaalsContact O-N 3.11Å; Q10-T14 PolarHBondContact O-OG1 2.92Å; Q10-T14 VanDerWaalsContact O-OG1 3.1Å; M11-T14 PolarHBondContact O-N 2.62Å; T14-K16 VanDerWaalsContact C-N 3.3Å; T14-K16 PolarHBondContact O-N 3.33Å; T14-T17 WeakPolarHBondContact CA-OG1 3.26Å; T14-T17 PolarHBondContact O-N 3.17Å; T14-T17 PolarHBondContact O-OG1 2.96Å; T14-A18 PolarHBondContact O-N 2.75Å; T14-A18 VanDerWaalsContact O-N 3.07Å; T14-R253 HydrophobicContact CG2-CB 3.82Å; T14-R253 HydrophobicContact CG2-CG 4.42Å
15E65.5Low70.6Confident35 Ų3584.5 Ų84.516%0.16444%0.438CS..Hα-helixtrans-57.2-42.5171.5-74.8169.4-174.300111.8M11 T17 W19M11-E15 WeakPolarHBondContact O-CB 3.49Å; M11-E15 VanDerWaalsContact O-CG 3.27Å; M11-E15 WeakPolarHBondContact O-CG 3.37Å; M11-E15 PolarHBondContact O-N 2.72Å; E15-T17 VanDerWaalsContact C-N 3.26Å; E15-T17 PolarHBondContact O-N 3.47Å; E15-W19 HydrophobicContact CB-CD2 4.43Å; E15-W19 HydrophobicContact CB-CE3 4.03Å; E15-W19 HydrophobicContact CB-CH2 4.25Å; E15-W19 HydrophobicContact CB-CZ3 3.94Å; E15-W19 HydrophobicContact CG-CH2 3.94Å; E15-W19 HydrophobicContact CG-CZ2 4.27Å; E15-W19 HydrophobicContact CG-CZ3 4.12Å; E15-W19 VanDerWaalsContact O-CB 3.27Å; E15-W19 WeakPolarHBondContact O-CB 3.37Å; E15-W19 VanDerWaalsContact O-CG 3.31Å; E15-W19 PolarHBondContact O-N 3.08Å; E15-W19 VanDerWaalsContact O-N 3.11Å
16K67.9Low73.1Confident149 Ų14983.9 Ų83.965%0.64843%0.431SS*.Hα-helixtrans-63.3-30.4179.4-82.5174.6-175.8175.20113.7K12 N13 T14K12-K16 WeakPolarHBondContact O-CD 3.21Å; K12-K16 VanDerWaalsContact O-CG 3.26Å; K12-K16 WeakPolarHBondContact O-CG 3.48Å; K12-K16 PolarHBondContact O-N 3.21Å; N13-K16 PolarHBondContact O-N 2.88Å; T14-K16 VanDerWaalsContact C-N 3.3Å; T14-K16 PolarHBondContact O-N 3.33Å
17T82.4Confident75.4Confident79 Ų7978.4 Ų78.449%0.48540%0.402SS..Hα-helixtrans-84.3-48.6-178.820.90000111.1N13 T14 E15 W19 E20N13-T17 PolarHBondContact O-N 2.66Å; N13-T17 PolarHBondContact O-OG1 3.35Å; T14-T17 WeakPolarHBondContact CA-OG1 3.26Å; T14-T17 PolarHBondContact O-N 3.17Å; T14-T17 PolarHBondContact O-OG1 2.96Å; E15-T17 VanDerWaalsContact C-N 3.26Å; E15-T17 PolarHBondContact O-N 3.47Å; T17-W19 PolarHBondContact O-N 3.44Å; T17-E20 VanDerWaalsContact O-CB 3.31Å; T17-E20 WeakPolarHBondContact O-CB 3.16Å; T17-E20 PolarHBondContact O-N 3.07Å; T17-E20 VanDerWaalsContact O-N 3.17Å
18A92.3Very high77.5Confident0 Ų076.4 Ų76.40%039%0.392CS..Hα-helixtrans-59.1-36.717800000113T14 P254 E256 R296T14-A18 PolarHBondContact O-N 2.75Å; T14-A18 VanDerWaalsContact O-N 3.07Å; A18-P254 HydrophobicContact CB-CB 3.99Å; A18-P254 HydrophobicContact CB-CG 3.62Å; A18-E256 HydrophobicContact CB-CG 3.8Å; A18-R296 PolarHBondContact O-NH1 3.24Å
19W94.8Very high79.8Confident19 Ų1975.3 Ų75.37%0.07239%0.392CS..THydrogen-bonded Turntrans-93.111.2-177.7-58.4-18000114.4E15 T17 G21 F22 W27 K28 L197 Y198E15-W19 HydrophobicContact CB-CD2 4.43Å; E15-W19 HydrophobicContact CB-CE3 4.03Å; E15-W19 HydrophobicContact CB-CH2 4.25Å; E15-W19 HydrophobicContact CB-CZ3 3.94Å; E15-W19 HydrophobicContact CG-CH2 3.94Å; E15-W19 HydrophobicContact CG-CZ2 4.27Å; E15-W19 HydrophobicContact CG-CZ3 4.12Å; E15-W19 VanDerWaalsContact O-CB 3.27Å; E15-W19 WeakPolarHBondContact O-CB 3.37Å; E15-W19 VanDerWaalsContact O-CG 3.31Å; E15-W19 PolarHBondContact O-N 3.08Å; E15-W19 VanDerWaalsContact O-N 3.11Å; T17-W19 PolarHBondContact O-N 3.44Å; W19-G21 PolarHBondContact O-N 2.94Å; W19-F22 HydrophobicContact CB-CD2 4.34Å; W19-F22 PolarHBondContact O-N 3.1Å; W19-F22 VanDerWaalsContact O-N 3.13Å; W19-W27 HydrophobicContact CB-CH2 3.8Å; W19-W27 HydrophobicContact CB-CZ3 4.42Å; W19-W27 AromaticContact CD1-CH2 3.93Å; W19-W27 AromaticContact CD1-CZ3 3.86Å; W19-W27 AromaticContact CD2-CH2 3.74Å; W19-W27 HydrophobicContact CD2-CH2 3.74Å; W19-W27 AromaticContact CD2-CZ3 3.46Å; W19-W27 HydrophobicContact CD2-CZ3 3.46Å; W19-W27 VanDerWaalsContact CD2-CZ3 3.46Å; W19-W27 AromaticContact CE2-CZ3 3.54Å; W19-W27 HydrophobicContact CE3-CH2 4.19Å; W19-W27 AromaticContact CE3-CZ3 3.9Å; W19-W27 HydrophobicContact CE3-CZ3 3.9Å; W19-W27 AromaticContact CG-CH2 3.55Å; W19-W27 HydrophobicContact CG-CH2 3.55Å; W19-W27 AromaticContact CG-CZ3 3.69Å; W19-W27 HydrophobicContact CG-CZ3 3.69Å; W19-W27 HydrophobicContact CH2-CZ3 4.44Å; W19-W27 HydrophobicContact CZ2-CZ3 4.05Å; W19-W27 HydrophobicContact CZ3-CZ3 4.37Å; W19-W27 AromaticContact NE1-CZ3 3.77Å; W19-K28 HydrophobicContact CE3-CB 4.48Å; W19-K28 HydrophobicContact CE3-CG 4.05Å; W19-K28 HydrophobicContact CZ3-CB 4.08Å; W19-K28 HydrophobicContact CZ3-CG 4.13Å; W19-L197 PolarHBondContact NE1-O 3.23Å; W19-Y198 HydrophobicContact CH2-CD1 4.49Å; W19-Y198 HydrophobicContact CZ2-CD1 4.08Å; W19-Y198 HydrophobicContact CZ2-CE1 4.45Å
20E90.9Very high82Confident124 Ų12474.9 Ų74.958%0.57939%0.387SS*.THydrogen-bonded Turntrans-60.3125.9-179.6-173.2-179.9-158.700111.3T17T17-E20 VanDerWaalsContact O-CB 3.31Å; T17-E20 WeakPolarHBondContact O-CB 3.16Å; T17-E20 PolarHBondContact O-N 3.07Å; T17-E20 VanDerWaalsContact O-N 3.17Å
21G92.2Very high84.1Confident66 Ų6670.1 Ų70.168%0.6837%0.366SS*.THydrogen-bonded Turntrans88.8-7.6-179.800000114.9W19W19-G21 PolarHBondContact O-N 2.94Å
22F96.9Very high86.2Confident14 Ų1469.3 Ų69.36%0.06136%0.362CS..  trans-85.4134.5177.2-61.1-41.4000112.9W19 W27 K28 F36 N40 I292 Y293 R296W19-F22 HydrophobicContact CB-CD2 4.34Å; W19-F22 PolarHBondContact O-N 3.1Å; W19-F22 VanDerWaalsContact O-N 3.13Å; F22-W27 HydrophobicContact CB-CH2 4.05Å; F22-W27 HydrophobicContact CB-CZ2 3.7Å; F22-W27 HydrophobicContact CD2-CH2 4.31Å; F22-K28 PolarHBondContact O-NZ 3.11Å; F22-F36 HydrophobicContact CB-CE2 4.2Å; F22-F36 HydrophobicContact CD1-CE2 4.28Å; F22-F36 AromaticContact CD2-CE2 3.7Å; F22-F36 HydrophobicContact CD2-CE2 3.7Å; F22-F36 HydrophobicContact CD2-CZ 4.19Å; F22-F36 HydrophobicContact CE1-CZ 4.46Å; F22-F36 HydrophobicContact CE2-CE2 4.08Å; F22-F36 HydrophobicContact CE2-CZ 4.09Å; F22-F36 AromaticContact CG-CE2 3.83Å; F22-F36 HydrophobicContact CG-CE2 3.83Å; F22-F36 HydrophobicContact CG-CZ 4.44Å; F22-F36 HydrophobicContact CZ-CZ 4.23Å; F22-N40 WeakPolarHBondContact CA-OD1 3.43Å; F22-N40 WeakPolarHBondContact CB-OD1 3.47Å; F22-N40 HydrophobicContact CD1-CB 4.47Å; F22-I292 HydrophobicContact CD1-CG2 3.97Å; F22-I292 HydrophobicContact CE1-CG2 3.42Å; F22-I292 VanDerWaalsContact CE1-CG2 3.42Å; F22-I292 HydrophobicContact CZ-CG2 3.99Å; F22-Y293 HydrophobicContact CE2-CD1 4.25Å; F22-Y293 AromaticContact CE2-CE1 3.77Å; F22-Y293 HydrophobicContact CE2-CE1 3.77Å; F22-Y293 AromaticContact CZ-CD1 3.9Å; F22-Y293 HydrophobicContact CZ-CD1 3.9Å; F22-Y293 AromaticContact CZ-CE1 3.89Å; F22-Y293 HydrophobicContact CZ-CE1 3.89Å; F22-Y293 HydrophobicContact CZ-CG 4.26Å; F22-R296 HydrophobicContact CE1-CB 4.36Å; F22-R296 HydrophobicContact CE1-CG 4.44Å; F22-R296 VanDerWaalsContact CZ-NH1 3.3Å
23N96.7Very high88.1Confident105 Ų10564.1 Ų64.156%0.56134%0.34SS*.  trans-82.3170.8175.9-60.6-53.8000111.6W27 T39 N40N23-W27 PolarHBondContact O-NE1 3.16Å; N23-T39 WeakPolarHBondContact CB-O 3.28Å; N23-T39 PolarHBondContact O-OG1 3.48Å; N23-N40 PolarHBondContact N-OD1 3.05Å; N23-N40 PolarHBondContact O-ND2 3.48Å
24G94.2Very high89.9Confident29 Ų2963.5 Ų63.530%0.29933%0.33SS..  trans95.7158.7179.800000113.7K28G24-K28 WeakPolarHBondContact O-CE 3.45Å; G24-K28 PolarHBondContact O-NZ 3.03Å
25R92.5Very high91.8Very high196 Ų19662.7 Ų62.774%0.7432%0.324SS*.SBendtrans-124.2-42.2-175.8-170.2-175.8851071.4112.8K28 S29R25-K28 PolarHBondContact O-N 2.99Å; R25-S29 PolarHBondContact O-OG 3.11Å
26L95Very high93.3Very high70 Ų7061 Ų6137%0.36632%0.316SS..G310 helixtrans-67.8-49.5-170.9-61.8171.4000110.2K28 S29 E30 D35L26-K28 PolarHBondContact O-N 3.45Å; L26-S29 PolarHBondContact O-N 3.36Å; L26-S29 PolarHBondContact O-OG 2.99Å; L26-E30 WeakPolarHBondContact O-CG 3.46Å; L26-E30 PolarHBondContact O-N 3.45Å; L26-D35 HydrophobicContact CB-CB 4.5Å; L26-D35 WeakPolarHBondContact CB-OD2 3.41Å; L26-D35 PolarHBondContact N-OD2 3.42Å
27W96.6Very high94.8Very high0 Ų054.3 Ų54.30%029%0.287CS..G310 helixtrans-58.6-18.4178.472.3-99.3000114.8W19 F22 N23 E30 N32 D35 F36 L197 Y198W19-W27 HydrophobicContact CB-CH2 3.8Å; W19-W27 HydrophobicContact CB-CZ3 4.42Å; W19-W27 AromaticContact CD1-CH2 3.93Å; W19-W27 AromaticContact CD1-CZ3 3.86Å; W19-W27 AromaticContact CD2-CH2 3.74Å; W19-W27 HydrophobicContact CD2-CH2 3.74Å; W19-W27 AromaticContact CD2-CZ3 3.46Å; W19-W27 HydrophobicContact CD2-CZ3 3.46Å; W19-W27 VanDerWaalsContact CD2-CZ3 3.46Å; W19-W27 AromaticContact CE2-CZ3 3.54Å; W19-W27 HydrophobicContact CE3-CH2 4.19Å; W19-W27 AromaticContact CE3-CZ3 3.9Å; W19-W27 HydrophobicContact CE3-CZ3 3.9Å; W19-W27 AromaticContact CG-CH2 3.55Å; W19-W27 HydrophobicContact CG-CH2 3.55Å; W19-W27 AromaticContact CG-CZ3 3.69Å; W19-W27 HydrophobicContact CG-CZ3 3.69Å; W19-W27 HydrophobicContact CH2-CZ3 4.44Å; W19-W27 HydrophobicContact CZ2-CZ3 4.05Å; W19-W27 HydrophobicContact CZ3-CZ3 4.37Å; W19-W27 AromaticContact NE1-CZ3 3.77Å; F22-W27 HydrophobicContact CB-CH2 4.05Å; F22-W27 HydrophobicContact CB-CZ2 3.7Å; F22-W27 HydrophobicContact CD2-CH2 4.31Å; N23-W27 PolarHBondContact O-NE1 3.16Å; W27-E30 CarbonylContact C-O 3.42Å; W27-E30 WeakPolarHBondContact CA-O 3.25Å; W27-N32 HydrophobicContact CB-CB 4.33Å; W27-N32 WeakPolarHBondContact CB-O 3.35Å; W27-D35 HydrophobicContact CB-CB 4.24Å; W27-D35 VanDerWaalsContact CD1-OD2 3.23Å; W27-D35 PolarHBondContact N-OD2 3.44Å; W27-F36 HydrophobicContact CB-CB 3.93Å; W27-F36 HydrophobicContact CD2-CB 3.99Å; W27-F36 AromaticContact CD2-CD2 3.8Å; W27-F36 HydrophobicContact CD2-CD2 3.8Å; W27-F36 HydrophobicContact CD2-CG 4.36Å; W27-F36 AromaticContact CE2-CD2 3.63Å; W27-F36 HydrophobicContact CE3-CB 4.44Å; W27-F36 AromaticContact CE3-CD2 4Å; W27-F36 HydrophobicContact CE3-CD2 4Å; W27-F36 HydrophobicContact CG-CB 3.74Å; W27-F36 HydrophobicContact CG-CD2 4.38Å; W27-F36 AromaticContact CH2-CD2 3.88Å; W27-F36 HydrophobicContact CH2-CD2 3.88Å; W27-F36 HydrophobicContact CH2-CE2 4.05Å; W27-F36 AromaticContact CZ2-CD2 3.68Å; W27-F36 HydrophobicContact CZ2-CD2 3.68Å; W27-F36 HydrophobicContact CZ2-CE2 4.07Å; W27-F36 HydrophobicContact CZ3-CD2 4.03Å; W27-F36 HydrophobicContact CZ3-CE2 4.44Å; W27-L197 HydrophobicContact CE3-CD1 3.92Å; W27-L197 HydrophobicContact CE3-CD2 4.29Å; W27-L197 HydrophobicContact CE3-CG 4.31Å; W27-L197 HydrophobicContact CH2-CD1 4.41Å; W27-L197 HydrophobicContact CZ3-CD1 3.66Å; W27-L197 HydrophobicContact CZ3-CG 4.41Å; W27-Y198 WeakPolarHBondContact O-CE1 3.24Å; W27-Y198 PolarHBondContact O-OH 2.95Å
28K94Very high95.6Very high79 Ų7951.9 Ų51.934%0.34327%0.27SS..G310 helixtrans-83-17.1174.7-62.7179.8-179.7167.10113.2W19 F22 G24 R25 L26W19-K28 HydrophobicContact CE3-CB 4.48Å; W19-K28 HydrophobicContact CE3-CG 4.05Å; W19-K28 HydrophobicContact CZ3-CB 4.08Å; W19-K28 HydrophobicContact CZ3-CG 4.13Å; F22-K28 PolarHBondContact O-NZ 3.11Å; G24-K28 WeakPolarHBondContact O-CE 3.45Å; G24-K28 PolarHBondContact O-NZ 3.03Å; R25-K28 PolarHBondContact O-N 2.99Å; L26-K28 PolarHBondContact O-N 3.45Å
29S91.5Very high95.9Very high74 Ų7454.1 Ų54.152%0.51728%0.284SS..THydrogen-bonded Turntrans-110.3-15.4-178.353.10000114.2R25 L26R25-S29 PolarHBondContact O-OG 3.11Å; L26-S29 PolarHBondContact O-N 3.36Å; L26-S29 PolarHBondContact O-OG 2.99Å
30E94.1Very high96Very high86 Ų8654.2 Ų54.240%0.40229%0.286SS..SBendtrans-149.4162.3-179.755.3175.7-143.700110.5L26 W27 N32 Y198L26-E30 WeakPolarHBondContact O-CG 3.46Å; L26-E30 PolarHBondContact O-N 3.45Å; W27-E30 CarbonylContact C-O 3.42Å; W27-E30 WeakPolarHBondContact CA-O 3.25Å; E30-N32 HydrophobicContact CG-CB 4.18Å; E30-N32 PolarHBondContact O-N 3.48Å; E30-N32 VanDerWaalsContact O-N 3.09Å; E30-N32 PolarHBondContact OE1-ND2 3.19Å; E30-Y198 PolarHBondContact O-OH 2.9Å; E30-Y198 VanDerWaalsContact O-OH 3.09Å
31I97.2Very high96.4Very high33 Ų3348.7 Ų48.717%0.16926%0.26CS..  trans-71.2103.7173.5-59.6175.6000109.2R194 Y198 Y202 L203 E206I31-R194 HydrophobicContact CG2-CG 4.02Å; I31-R194 VanDerWaalsContact CG2-CZ 3.41Å; I31-Y198 HydrophobicContact CB-CE2 4.38Å; I31-Y198 HydrophobicContact CG2-CD2 4.43Å; I31-Y198 HydrophobicContact CG2-CE2 3.89Å; I31-Y202 HydrophobicContact CG1-CE1 3.91Å; I31-L203 HydrophobicContact CD1-CD2 3.64Å; I31-L203 HydrophobicContact CG1-CD2 4.23Å; I31-E206 HydrophobicContact CD1-CB 3.82Å; I31-E206 HydrophobicContact CD1-CG 3.78Å; I31-E206 HydrophobicContact CG1-CG 4.08Å
32N97.6Very high96.7Very high33 Ų3349 Ų4918%0.17625%0.248CC..  trans-151.776.4-176.3-162.4-25.9000111.3W27 E30 R34 D35 F36 Y198W27-N32 HydrophobicContact CB-CB 4.33Å; W27-N32 WeakPolarHBondContact CB-O 3.35Å; E30-N32 HydrophobicContact CG-CB 4.18Å; E30-N32 PolarHBondContact O-N 3.48Å; E30-N32 VanDerWaalsContact O-N 3.09Å; E30-N32 PolarHBondContact OE1-ND2 3.19Å; N32-R34 VanDerWaalsContact C-N 3.28Å; N32-R34 PolarHBondContact O-N 3.07Å; N32-D35 HydrophobicContact CB-CB 4.14Å; N32-D35 VanDerWaalsContact CG-CB 3.5Å; N32-D35 PolarHBondContact O-N 3.04Å; N32-D35 WeakPolarHBondContact OD1-CB 3.47Å; N32-D35 PolarHBondContact OD1-N 2.91Å; N32-F36 PolarHBondContact O-N 3.01Å; N32-Y198 PolarHBondContact N-OH 3.37Å
33V98.6Very high96.8Very high3 Ų350.1 Ų50.12%0.01826%0.257CS..Hα-helixtrans-63.1-34.8-179.6-1770000111.6F36 I37 D191 R193 R194 L197 Y198 F289V33-F36 WeakPolarHBondContact O-CB 3.49Å; V33-F36 PolarHBondContact O-N 3.35Å; V33-I37 HydrophobicContact CG1-CD1 3.99Å; V33-I37 HydrophobicContact CG1-CG1 4.34Å; V33-I37 WeakPolarHBondContact O-CG1 3.47Å; V33-I37 PolarHBondContact O-N 3.38Å; V33-D191 VanDerWaalsContact CG2-OD2 3.28Å; V33-D191 WeakPolarHBondContact CG2-OD2 3.4Å; V33-R193 HydrophobicContact CG1-CB 3.96Å; V33-R194 HydrophobicContact CG2-CG 3.72Å; V33-L197 HydrophobicContact CG2-CD2 4.13Å; V33-Y198 HydrophobicContact CG2-CE2 4.14Å; V33-F289 HydrophobicContact CG1-CD2 3.95Å; V33-F289 HydrophobicContact CG1-CE2 4.22Å
34R98Very high96.9Very high92 Ų9247.2 Ų47.235%0.34724%0.238SC..Hα-helixtrans-59.5-47.1175.1-172-126.5-179.1-156.8-5.5112.4N32 F36 I37 Q38 D418 D419N32-R34 VanDerWaalsContact C-N 3.28Å; N32-R34 PolarHBondContact O-N 3.07Å; R34-F36 VanDerWaalsContact C-N 3.32Å; R34-F36 PolarHBondContact O-N 3.34Å; R34-I37 PolarHBondContact O-N 3.07Å; R34-Q38 HydrophobicContact CG-CG 4.47Å; R34-Q38 WeakPolarHBondContact O-CB 3.44Å; R34-Q38 VanDerWaalsContact O-CG 3.32Å; R34-Q38 WeakPolarHBondContact O-CG 3.38Å; R34-Q38 PolarHBondContact O-N 3.2Å; R34-D418 IonicContact CZ-OD1 3.23Å; R34-D418 VanDerWaalsContact CZ-OD1 3.31Å; R34-D418 IonicContact CZ-OD2 2.77Å; R34-D418 IonicContact NE-OD1 3.73Å; R34-D418 PolarHBondContact NE-OD1 3.03Å; R34-D418 IonicContact NE-OD2 2.76Å; R34-D418 VanDerWaalsContact NH2-CG 3.32Å; R34-D418 IonicContact NH2-OD1 3.63Å; R34-D418 PolarHBondContact NH2-OD1 3.24Å; R34-D418 IonicContact NH2-OD2 3.19Å; R34-D418 PolarHBondContact NH2-OD2 2.98Å; R34-D419 HydrophobicContact CB-CB 3.96Å; R34-D419 HydrophobicContact CG-CB 3.65Å
35D98.2Very high97.1Very high31 Ų3153 Ų5317%0.16626%0.258CS..Hα-helixtrans-62.7-39.6175.8-177.570.7000111.5L26 W27 N32 T39L26-D35 HydrophobicContact CB-CB 4.5Å; L26-D35 WeakPolarHBondContact CB-OD2 3.41Å; L26-D35 PolarHBondContact N-OD2 3.42Å; W27-D35 HydrophobicContact CB-CB 4.24Å; W27-D35 VanDerWaalsContact CD1-OD2 3.23Å; W27-D35 PolarHBondContact N-OD2 3.44Å; N32-D35 HydrophobicContact CB-CB 4.14Å; N32-D35 VanDerWaalsContact CG-CB 3.5Å; N32-D35 PolarHBondContact O-N 3.04Å; N32-D35 WeakPolarHBondContact OD1-CB 3.47Å; N32-D35 PolarHBondContact OD1-N 2.91Å; D35-T39 WeakPolarHBondContact O-CB 3.36Å; D35-T39 WeakPolarHBondContact O-CG2 3.34Å; D35-T39 PolarHBondContact O-N 3.28Å; D35-T39 VanDerWaalsContact O-N 3.12Å; D35-T39 PolarHBondContact O-OG1 2.89Å
36F98.6Very high97.4Very high0 Ų045 Ų450%024%0.236CC..Hα-helixtrans-58.8-49.1172.8171.4-103.8000111.7F22 W27 N32 V33 R34 T39 N40 L197 F289 I292 Y293F22-F36 HydrophobicContact CB-CE2 4.2Å; F22-F36 HydrophobicContact CD1-CE2 4.28Å; F22-F36 AromaticContact CD2-CE2 3.7Å; F22-F36 HydrophobicContact CD2-CE2 3.7Å; F22-F36 HydrophobicContact CD2-CZ 4.19Å; F22-F36 HydrophobicContact CE1-CZ 4.46Å; F22-F36 HydrophobicContact CE2-CE2 4.08Å; F22-F36 HydrophobicContact CE2-CZ 4.09Å; F22-F36 AromaticContact CG-CE2 3.83Å; F22-F36 HydrophobicContact CG-CE2 3.83Å; F22-F36 HydrophobicContact CG-CZ 4.44Å; F22-F36 HydrophobicContact CZ-CZ 4.23Å; W27-F36 HydrophobicContact CB-CB 3.93Å; W27-F36 HydrophobicContact CD2-CB 3.99Å; W27-F36 AromaticContact CD2-CD2 3.8Å; W27-F36 HydrophobicContact CD2-CD2 3.8Å; W27-F36 HydrophobicContact CD2-CG 4.36Å; W27-F36 AromaticContact CE2-CD2 3.63Å; W27-F36 HydrophobicContact CE3-CB 4.44Å; W27-F36 AromaticContact CE3-CD2 4Å; W27-F36 HydrophobicContact CE3-CD2 4Å; W27-F36 HydrophobicContact CG-CB 3.74Å; W27-F36 HydrophobicContact CG-CD2 4.38Å; W27-F36 AromaticContact CH2-CD2 3.88Å; W27-F36 HydrophobicContact CH2-CD2 3.88Å; W27-F36 HydrophobicContact CH2-CE2 4.05Å; W27-F36 AromaticContact CZ2-CD2 3.68Å; W27-F36 HydrophobicContact CZ2-CD2 3.68Å; W27-F36 HydrophobicContact CZ2-CE2 4.07Å; W27-F36 HydrophobicContact CZ3-CD2 4.03Å; W27-F36 HydrophobicContact CZ3-CE2 4.44Å; N32-F36 PolarHBondContact O-N 3.01Å; V33-F36 WeakPolarHBondContact O-CB 3.49Å; V33-F36 PolarHBondContact O-N 3.35Å; R34-F36 VanDerWaalsContact C-N 3.32Å; R34-F36 PolarHBondContact O-N 3.34Å; F36-T39 PolarHBondContact O-N 2.64Å; F36-T39 PolarHBondContact O-OG1 3.3Å; F36-N40 HydrophobicContact CE2-CB 4.41Å; F36-N40 WeakPolarHBondContact O-CB 3.41Å; F36-N40 PolarHBondContact O-N 2.74Å; F36-N40 PolarHBondContact O-ND2 3.24Å; F36-L197 HydrophobicContact CB-CD1 4.47Å; F36-L197 HydrophobicContact CB-CD2 3.61Å; F36-L197 HydrophobicContact CD1-CD1 3.98Å; F36-L197 HydrophobicContact CD1-CD2 3.96Å; F36-L197 HydrophobicContact CD2-CD1 3.63Å; F36-L197 HydrophobicContact CD2-CD2 4.32Å; F36-L197 HydrophobicContact CE1-CD1 4.06Å; F36-L197 HydrophobicContact CE2-CD1 3.71Å; F36-L197 HydrophobicContact CG-CD1 3.75Å; F36-L197 HydrophobicContact CG-CD2 3.7Å; F36-L197 HydrophobicContact CG-CG 4.41Å; F36-L197 HydrophobicContact CZ-CD1 3.91Å; F36-F289 AromaticContact CD1-CD2 3.76Å; F36-F289 HydrophobicContact CD1-CD2 3.76Å; F36-F289 AromaticContact CD1-CE2 3.66Å; F36-F289 HydrophobicContact CD1-CE2 3.66Å; F36-F289 AromaticContact CE1-CD2 3.67Å; F36-F289 HydrophobicContact CE1-CD2 3.67Å; F36-F289 AromaticContact CE1-CE2 3.45Å; F36-F289 HydrophobicContact CE1-CE2 3.45Å; F36-F289 VanDerWaalsContact CE1-CE2 3.45Å; F36-F289 HydrophobicContact CE1-CZ 4.49Å; F36-I292 HydrophobicContact CD1-CD1 3.97Å; F36-I292 HydrophobicContact CE1-CB 4.27Å; F36-I292 HydrophobicContact CE1-CD1 3.55Å; F36-I292 HydrophobicContact CE1-CG2 4.01Å; F36-I292 HydrophobicContact CE2-CG2 4.34Å; F36-I292 HydrophobicContact CZ-CB 4.28Å; F36-I292 HydrophobicContact CZ-CD1 4.18Å; F36-I292 HydrophobicContact CZ-CG2 3.55Å; F36-Y293 AromaticContact CE1-CE2 3.88Å; F36-Y293 HydrophobicContact CE1-CE2 3.88Å; F36-Y293 AromaticContact CZ-CE2 3.73Å; F36-Y293 HydrophobicContact CZ-CE2 3.73Å
37I98.7Very high97.5Very high7 Ų743.9 Ų43.94%0.03624%0.237CC..Hα-helixtrans-57.9-59.5178.5-68.4165.5000109.5V33 R34 T39 N40 Y41 R193 T288 F289 I292 L355V33-I37 HydrophobicContact CG1-CD1 3.99Å; V33-I37 HydrophobicContact CG1-CG1 4.34Å; V33-I37 WeakPolarHBondContact O-CG1 3.47Å; V33-I37 PolarHBondContact O-N 3.38Å; R34-I37 PolarHBondContact O-N 3.07Å; I37-T39 PolarHBondContact O-N 2.75Å; I37-N40 PolarHBondContact O-N 3.3Å; I37-Y41 HydrophobicContact CG2-CD1 4.28Å; I37-Y41 HydrophobicContact CG2-CG 4.41Å; I37-Y41 VanDerWaalsContact O-CD1 3.23Å; I37-Y41 WeakPolarHBondContact O-CD1 3.27Å; I37-Y41 PolarHBondContact O-N 3.08Å; I37-R193 VanDerWaalsContact CD1-NH1 3.32Å; I37-T288 HydrophobicContact CG2-CG2 3.99Å; I37-F289 HydrophobicContact CD1-CB 4.12Å; I37-F289 HydrophobicContact CG1-CB 4.21Å; I37-F289 HydrophobicContact CG1-CD2 4.26Å; I37-I292 HydrophobicContact CB-CD1 4.41Å; I37-I292 HydrophobicContact CG1-CD1 4.21Å; I37-L355 HydrophobicContact CG2-CD2 4.19Å
38Q98.3Very high97.6Very high28 Ų2845.2 Ų45.213%0.13125%0.248CC..Hα-helixtrans-55.8-32-173.7-73.9-63.8-34.700113.7R34 R353 D418R34-Q38 HydrophobicContact CG-CG 4.47Å; R34-Q38 WeakPolarHBondContact O-CB 3.44Å; R34-Q38 VanDerWaalsContact O-CG 3.32Å; R34-Q38 WeakPolarHBondContact O-CG 3.38Å; R34-Q38 PolarHBondContact O-N 3.2Å; Q38-R353 PolarHBondContact O-NH2 3.07Å; Q38-R353 VanDerWaalsContact O-NH2 3.16Å; Q38-D418 PolarHBondContact NE2-OD2 2.65Å
39T98.3Very high97.8Very high48 Ų4848 Ų4829%0.29427%0.267SS..Hα-helixtrans-89-11.5-179.356.10000114.5N23 D35 F36 I37N23-T39 WeakPolarHBondContact CB-O 3.28Å; N23-T39 PolarHBondContact O-OG1 3.48Å; D35-T39 WeakPolarHBondContact O-CB 3.36Å; D35-T39 WeakPolarHBondContact O-CG2 3.34Å; D35-T39 PolarHBondContact O-N 3.28Å; D35-T39 VanDerWaalsContact O-N 3.12Å; D35-T39 PolarHBondContact O-OG1 2.89Å; F36-T39 PolarHBondContact O-N 2.64Å; F36-T39 PolarHBondContact O-OG1 3.3Å; I37-T39 PolarHBondContact O-N 2.75Å
40N98.7Very high98.1Very high20 Ų2046.1 Ų46.111%0.10725%0.249CC..Hα-helixtrans-130.7-20.7-170.8-67.4-76.1000116.4F22 N23 F36 I37 I292F22-N40 WeakPolarHBondContact CA-OD1 3.43Å; F22-N40 WeakPolarHBondContact CB-OD1 3.47Å; F22-N40 HydrophobicContact CD1-CB 4.47Å; N23-N40 PolarHBondContact N-OD1 3.05Å; N23-N40 PolarHBondContact O-ND2 3.48Å; F36-N40 HydrophobicContact CE2-CB 4.41Å; F36-N40 WeakPolarHBondContact O-CB 3.41Å; F36-N40 PolarHBondContact O-N 2.74Å; F36-N40 PolarHBondContact O-ND2 3.24Å; I37-N40 PolarHBondContact O-N 3.3Å; N40-I292 HydrophobicContact CB-CD1 4.15Å; N40-I292 HydrophobicContact CB-CG1 4.24Å; N40-I292 HydrophobicContact CB-CG2 3.66Å
41Y98.7Very high98.3Very high9 Ų943.5 Ų43.54%0.03524%0.237CC..  trans-68.7151.8-179.189.7-76.2000112I37 P43 T288 R353 T354 L355 T357I37-Y41 HydrophobicContact CG2-CD1 4.28Å; I37-Y41 HydrophobicContact CG2-CG 4.41Å; I37-Y41 VanDerWaalsContact O-CD1 3.23Å; I37-Y41 WeakPolarHBondContact O-CD1 3.27Å; I37-Y41 PolarHBondContact O-N 3.08Å; Y41-P43 HydrophobicContact CD2-CG 4.27Å; Y41-P43 HydrophobicContact CE2-CB 4.1Å; Y41-P43 HydrophobicContact CE2-CG 3.52Å; Y41-T288 HydrophobicContact CD2-CG2 3.86Å; Y41-T288 HydrophobicContact CG-CG2 4Å; Y41-R353 VanDerWaalsContact OH-CB 3.26Å; Y41-R353 WeakPolarHBondContact OH-CB 3.49Å; Y41-T354 WeakPolarHBondContact CE2-O 3.42Å; Y41-T354 PolarHBondContact OH-O 3.49Å; Y41-L355 HydrophobicContact CD1-CD2 4.33Å; Y41-L355 HydrophobicContact CD2-CD2 4.24Å; Y41-L355 HydrophobicContact CE1-CD2 3.94Å; Y41-L355 HydrophobicContact CE2-CD2 3.87Å; Y41-L355 HydrophobicContact CG-CD2 4.44Å; Y41-T357 HydrophobicContact CD2-CG2 4.05Å
42T98.7Very high98.4Very high71 Ų7142.7 Ų42.744%0.43624%0.236SC..  trans-110.7103.3177.8-57.90000108.8Y44T42-Y44 PolarHBondContact O-N 3.2Å
43P98.8Very high98.4Very high39 Ų3948 Ų4825%0.25326%0.26SS..  trans-52.9135.6173.7-19.826.4000110.9Y41 R353 T354 V356Y41-P43 HydrophobicContact CD2-CG 4.27Å; Y41-P43 HydrophobicContact CE2-CB 4.1Å; Y41-P43 HydrophobicContact CE2-CG 3.52Å; P43-R353 HydrophobicContact CG-CB 4.43Å; P43-T354 HydrophobicContact CB-CG2 3.94Å; P43-V356 WeakPolarHBondContact CA-O 3.31Å
44Y98.8Very high98.4Very high43 Ų4349 Ų4917%0.16927%0.266CS..  trans-119.2117.7178-176.4-109000110.3T42 G46 A47 F50 V356 K358 F361T42-Y44 PolarHBondContact O-N 3.2Å; Y44-G46 VanDerWaalsContact CZ-CA 3.49Å; Y44-A47 WeakPolarHBondContact CE1-O 3.32Å; Y44-A47 PolarHBondContact OH-O 3.14Å; Y44-F50 HydrophobicContact CD1-CE1 4.35Å; Y44-F50 AromaticContact CE1-CD1 3.96Å; Y44-F50 HydrophobicContact CE1-CD1 3.96Å; Y44-F50 AromaticContact CE1-CE1 3.56Å; Y44-F50 HydrophobicContact CE1-CE1 3.56Å; Y44-F50 AromaticContact CZ-CD1 3.78Å; Y44-F50 AromaticContact CZ-CE1 3.85Å; Y44-F50 WeakPolarHBondContact OH-CD1 3.47Å; Y44-V356 PolarHBondContact N-O 3.34Å; Y44-V356 WeakPolarHBondContact O-CG1 3.49Å; Y44-K358 HydrophobicContact CD1-CG 4.02Å; Y44-K358 HydrophobicContact CD2-CD 4.49Å; Y44-K358 HydrophobicContact CD2-CG 3.79Å; Y44-K358 HydrophobicContact CE1-CG 4.29Å; Y44-K358 HydrophobicContact CE2-CG 4.08Å; Y44-K358 HydrophobicContact CG-CG 3.76Å; Y44-F361 AromaticContact CD1-CD2 4Å; Y44-F361 HydrophobicContact CD1-CD2 4Å; Y44-F361 AromaticContact CD1-CE2 3.59Å; Y44-F361 HydrophobicContact CD1-CE2 3.59Å; Y44-F361 HydrophobicContact CD1-CZ 4.37Å; Y44-F361 HydrophobicContact CE1-CD2 4.19Å; Y44-F361 AromaticContact CE1-CE2 3.79Å; Y44-F361 HydrophobicContact CE1-CE2 3.79Å; Y44-F361 HydrophobicContact CE1-CZ 4.19Å
45E98.6Very high98.4Very high152 Ų15244.9 Ų44.971%0.7125%0.251SS*.  trans-109.49.1-177.8-60178.5-169.600112.6T354 P387E45-T354 HydrophobicContact CG-CG2 4.48Å; E45-P387 HydrophobicContact CB-CB 4.24Å; E45-P387 HydrophobicContact CB-CG 4.34Å; E45-P387 HydrophobicContact CG-CB 4.49Å; E45-P387 HydrophobicContact CG-CG 4.09Å
46G98.3Very high98.4Very high27 Ų2749.5 Ų49.528%0.27827%0.272SS..SBendtrans-83.9-173.3179.400000113.7Y44 F361Y44-G46 VanDerWaalsContact CZ-CA 3.49Å; G46-F361 WeakPolarHBondContact O-CZ 3.05Å
47A97.8Very high98.4Very high47 Ų4749.8 Ų49.839%0.38827%0.274SS..  trans-95.8-175.7178.500000112.1Y44 D49 F50Y44-A47 WeakPolarHBondContact CE1-O 3.32Å; Y44-A47 PolarHBondContact OH-O 3.14Å; A47-D49 PolarHBondContact O-N 3.02Å; A47-F50 WeakPolarHBondContact O-CD1 3.49Å
48A98.2Very high98.4Very high27 Ų2749.4 Ų49.422%0.22327%0.272CS..G310 helixtrans-79.96.5-178.600000114.7F50 L51 F361 Y393A48-F50 PolarHBondContact O-N 3.36Å; A48-F50 VanDerWaalsContact O-N 3.14Å; A48-L51 HydrophobicContact CB-CD1 3.8Å; A48-L51 WeakPolarHBondContact O-CB 3.41Å; A48-L51 WeakPolarHBondContact O-CG 3.5Å; A48-L51 PolarHBondContact O-N 3.05Å; A48-F361 HydrophobicContact CB-CD1 3.78Å; A48-F361 HydrophobicContact CB-CE1 3.97Å; A48-Y393 HydrophobicContact CB-CD1 4.21Å; A48-Y393 HydrophobicContact CB-CD2 3.43Å; A48-Y393 VanDerWaalsContact CB-CD2 3.43Å; A48-Y393 HydrophobicContact CB-CE1 4.42Å; A48-Y393 HydrophobicContact CB-CE2 3.74Å; A48-Y393 HydrophobicContact CB-CG 3.71Å
49D97.6Very high98.4Very high139 Ų13951.5 Ų51.574%0.74328%0.284SS*.G310 helixtrans-69.2-12.1-170.366.6-31.8000114.9A47A47-D49 PolarHBondContact O-N 3.02Å
50F98.4Very high98.5Very high34 Ų3452.6 Ų52.615%0.14929%0.286CS..G310 helixtrans-87.9-12.1177.876.1-85.1000113.8Y44 A47 A48 E305 K358 F361 R362Y44-F50 HydrophobicContact CD1-CE1 4.35Å; Y44-F50 AromaticContact CE1-CD1 3.96Å; Y44-F50 HydrophobicContact CE1-CD1 3.96Å; Y44-F50 AromaticContact CE1-CE1 3.56Å; Y44-F50 HydrophobicContact CE1-CE1 3.56Å; Y44-F50 AromaticContact CZ-CD1 3.78Å; Y44-F50 AromaticContact CZ-CE1 3.85Å; Y44-F50 WeakPolarHBondContact OH-CD1 3.47Å; A47-F50 WeakPolarHBondContact O-CD1 3.49Å; A48-F50 PolarHBondContact O-N 3.36Å; A48-F50 VanDerWaalsContact O-N 3.14Å; F50-E305 HydrophobicContact CD2-CG 4.14Å; F50-E305 WeakPolarHBondContact CD2-OE1 3.37Å; F50-E305 WeakPolarHBondContact CE2-OE1 3.46Å; F50-E305 VanDerWaalsContact O-CG 3.27Å; F50-E305 WeakPolarHBondContact O-CG 3.49Å; F50-K358 HydrophobicContact CD2-CD 3.91Å; F50-K358 HydrophobicContact CD2-CG 4.35Å; F50-K358 HydrophobicContact CE1-CB 4.37Å; F50-K358 HydrophobicContact CE1-CD 4.5Å; F50-K358 HydrophobicContact CE1-CG 4.01Å; F50-K358 HydrophobicContact CE2-CB 3.67Å; F50-K358 HydrophobicContact CE2-CD 3.76Å; F50-K358 HydrophobicContact CE2-CG 3.8Å; F50-K358 HydrophobicContact CG-CD 4.34Å; F50-K358 HydrophobicContact CZ-CB 3.52Å; F50-K358 HydrophobicContact CZ-CD 4.07Å; F50-K358 HydrophobicContact CZ-CG 3.6Å; F50-K358 WeakPolarHBondContact CZ-O 3.42Å; F50-F361 HydrophobicContact CE1-CB 4.08Å; F50-F361 HydrophobicContact CE1-CD2 4.31Å; F50-F361 HydrophobicContact CE1-CG 4.08Å; F50-F361 HydrophobicContact CZ-CB 3.82Å; F50-F361 HydrophobicContact CZ-CG 4.28Å; F50-R362 HydrophobicContact CE2-CG 4.41Å
51L98.7Very high98.5Very high30 Ų3051.7 Ų51.716%0.15728%0.281CS..  trans-62.3148.4-173.4-70.1169.4000111.9A48 F361 R362 H365 Y393A48-L51 HydrophobicContact CB-CD1 3.8Å; A48-L51 WeakPolarHBondContact O-CB 3.41Å; A48-L51 WeakPolarHBondContact O-CG 3.5Å; A48-L51 PolarHBondContact O-N 3.05Å; L51-F361 HydrophobicContact CD1-CB 4.32Å; L51-F361 HydrophobicContact CD2-CB 3.97Å; L51-F361 HydrophobicContact CG-CB 4.44Å; L51-R362 HydrophobicContact CD2-CG 4.13Å; L51-H365 HydrophobicContact CD1-CB 3.93Å; L51-H365 HydrophobicContact CD2-CB 3.96Å; L51-H365 HydrophobicContact CG-CB 4.48Å; L51-Y393 HydrophobicContact CD1-CE1 3.85Å; L51-Y393 HydrophobicContact CD1-CE2 4.16Å; L51-Y393 WeakPolarHBondContact CD1-OH 3.25Å
52A98.5Very high98.4Very high16 Ų1651.9 Ų51.913%0.13228%0.282CS..  trans-112.3139.4-177.300000111.5E305 E306 Q309 H365 N369A52-E305 HydrophobicContact CB-CG 4.29Å; A52-E306 HydrophobicContact CB-CB 4.21Å; A52-Q309 HydrophobicContact CB-CB 4.36Å; A52-H365 PolarHBondContact O-CD2 3.4Å; A52-H365 PolarHBondContact O-NE2 2.92Å; A52-N369 PolarHBondContact O-ND2 3.02Å
53E98.4Very high98.4Very high145 Ų14549.8 Ų49.868%0.67827%0.274SS*.PPolyproline II helixtrans-56.5157.6171.4-64.6-61.5143.500112.3
54P98.1Very high98.3Very high24 Ų2450.5 Ų50.516%0.15627%0.273CS..PPolyproline II helixtrans-66.2140.6-18027.1-31.9000111T58 N369P54-T58 HydrophobicContact CB-CG2 3.91Å; P54-N369 HydrophobicContact CB-CB 4.04Å; P54-N369 WeakPolarHBondContact CD-OD1 3.12Å; P54-N369 HydrophobicContact CG-CB 4.29Å
55T98.6Very high98.3Very high5 Ų548.4 Ų48.43%0.03127%0.265CS..PPolyproline II helixtrans-68163.117469.50000111.7A57 T58 N59 E306 E310T55-A57 VanDerWaalsContact C-N 3.25Å; T55-A57 PolarHBondContact O-N 3.48Å; T55-A57 PolarHBondContact OG1-N 2.96Å; T55-T58 WeakPolarHBondContact O-CB 3.39Å; T55-T58 PolarHBondContact O-N 3.26Å; T55-T58 PolarHBondContact OG1-N 3.16Å; T55-T58 PolarHBondContact OG1-OG1 3.25Å; T55-N59 PolarHBondContact O-N 3.2Å; T55-N59 PolarHBondContact O-ND2 3.38Å; T55-E306 HydrophobicContact CG2-CG 3.65Å; T55-E310 HydrophobicContact CG2-CB 3.85Å; T55-E310 HydrophobicContact CG2-CG 4.11Å; T55-E310 WeakPolarHBondContact CG2-OE1 3.42Å; T55-E310 PolarHBondContact OG1-OE1 3.26Å
56E98.4Very high98.1Very high129 Ų12944.8 Ų44.860%0.60325%0.248SC*.Hα-helixtrans-57.6-39.2171.5-176.861.1-160.800112N59 Q60E56-N59 PolarHBondContact O-N 3.43Å; E56-Q60 HydrophobicContact CG-CG 4.48Å; E56-Q60 VanDerWaalsContact O-CG 3.3Å; E56-Q60 WeakPolarHBondContact O-CG 3.33Å; E56-Q60 PolarHBondContact O-N 3.17Å; E56-Q60 PolarHBondContact OE1-NE2 2.99Å
57A98.5Very high98Very high5 Ų548.3 Ų48.34%0.04126%0.257CS..Hα-helixtrans-61.7-46.8175.700000111.5T55 N59 Q60 L61 E104T55-A57 VanDerWaalsContact C-N 3.25Å; T55-A57 PolarHBondContact O-N 3.48Å; T55-A57 PolarHBondContact OG1-N 2.96Å; A57-N59 VanDerWaalsContact C-N 3.32Å; A57-N59 PolarHBondContact O-N 2.93Å; A57-Q60 PolarHBondContact O-N 3.49Å; A57-L61 WeakPolarHBondContact O-CB 3.33Å; A57-L61 WeakPolarHBondContact O-CG 3.41Å; A57-L61 PolarHBondContact O-N 3.17Å; A57-E104 HydrophobicContact CB-CB 3.99Å
58T98.7Very high98Very high0 Ų047 Ų470%024%0.243CC..Hα-helixtrans-55.4-49174.2-58.60000110.5P54 T55 Q60 L61 W62 D313 H314 M317 M370P54-T58 HydrophobicContact CB-CG2 3.91Å; T55-T58 WeakPolarHBondContact O-CB 3.39Å; T55-T58 PolarHBondContact O-N 3.26Å; T55-T58 PolarHBondContact OG1-N 3.16Å; T55-T58 PolarHBondContact OG1-OG1 3.25Å; T58-Q60 PolarHBondContact O-N 2.98Å; T58-L61 PolarHBondContact O-N 3.3Å; T58-W62 WeakPolarHBondContact O-CB 3.18Å; T58-W62 PolarHBondContact O-N 3.35Å; T58-D313 HydrophobicContact CG2-CB 3.83Å; T58-H314 WeakPolarHBondContact CA-NE2 3.49Å; T58-H314 PolarHBondContact OG1-NE2 3.38Å; T58-M317 HydrophobicContact CG2-CE 4.34Å; T58-M370 HydrophobicContact CG2-CG 4Å; T58-M370 HydrophobicContact CG2-SD 4.21Å
59N98.6Very high97.9Very high71 Ų7146.2 Ų46.238%0.3824%0.235SC..Hα-helixtrans-63-42.6-178.5-72.7-37.6000112.4T55 E56 A57 G63T55-N59 PolarHBondContact O-N 3.2Å; T55-N59 PolarHBondContact O-ND2 3.38Å; E56-N59 PolarHBondContact O-N 3.43Å; A57-N59 VanDerWaalsContact C-N 3.32Å; A57-N59 PolarHBondContact O-N 2.93Å; N59-G63 PolarHBondContact O-N 3.5Å
60Q98.5Very high97.7Very high72 Ų7245 Ų4534%0.33622%0.223SC..Hα-helixtrans-66.5-47.3178.7-71.9177.33.400112.2E56 A57 T58 G63 K64 L101E56-Q60 HydrophobicContact CG-CG 4.48Å; E56-Q60 VanDerWaalsContact O-CG 3.3Å; E56-Q60 WeakPolarHBondContact O-CG 3.33Å; E56-Q60 PolarHBondContact O-N 3.17Å; E56-Q60 PolarHBondContact OE1-NE2 2.99Å; A57-Q60 PolarHBondContact O-N 3.49Å; T58-Q60 PolarHBondContact O-N 2.98Å; Q60-G63 PolarHBondContact O-N 3.43Å; Q60-K64 WeakPolarHBondContact O-CB 3.48Å; Q60-K64 PolarHBondContact O-N 2.97Å; Q60-L101 HydrophobicContact CB-CD1 4.28Å
61L98.8Very high97.6Very high0 Ų047.5 Ų47.50%024%0.236CC..Hα-helixtrans-66.7-42.5179.5-68.7168.8000111.6A57 T58 K64 L65 I97 L101 E104 E105 M317A57-L61 WeakPolarHBondContact O-CB 3.33Å; A57-L61 WeakPolarHBondContact O-CG 3.41Å; A57-L61 PolarHBondContact O-N 3.17Å; T58-L61 PolarHBondContact O-N 3.3Å; L61-K64 PolarHBondContact O-N 3.2Å; L61-L65 WeakPolarHBondContact O-CB 3.36Å; L61-L65 PolarHBondContact O-N 2.93Å; L61-I97 HydrophobicContact CB-CD1 4.27Å; L61-I97 HydrophobicContact CD2-CB 4.24Å; L61-I97 HydrophobicContact CD2-CD1 4.18Å; L61-I97 HydrophobicContact CD2-CG2 4.41Å; L61-L101 HydrophobicContact CD2-CB 3.79Å; L61-L101 HydrophobicContact CD2-CD1 4.3Å; L61-E104 HydrophobicContact CD1-CB 4.31Å; L61-E104 HydrophobicContact CG-CB 4.48Å; L61-E105 HydrophobicContact CD1-CB 4.48Å; L61-E105 HydrophobicContact CD1-CG 3.87Å; L61-E105 HydrophobicContact CD2-CG 3.73Å; L61-E105 HydrophobicContact CG-CG 4.48Å; L61-M317 HydrophobicContact CB-CE 3.93Å; L61-M317 HydrophobicContact CB-SD 3.64Å
62W98Very high97.4Very high14 Ų1446.6 Ų46.65%0.05323%0.23CC..Hα-helixtrans-64.7-45.7176.8-175.9-122.3000111.5T58 K64 L65 Q66 M317 R320 M370T58-W62 WeakPolarHBondContact O-CB 3.18Å; T58-W62 PolarHBondContact O-N 3.35Å; W62-K64 VanDerWaalsContact C-N 3.28Å; W62-K64 PolarHBondContact O-N 3.32Å; W62-L65 HydrophobicContact CE3-CB 4.38Å; W62-L65 HydrophobicContact CE3-CD2 3.87Å; W62-L65 HydrophobicContact CE3-CG 4.41Å; W62-L65 HydrophobicContact CZ3-CD2 3.62Å; W62-L65 HydrophobicContact CZ3-CG 4.24Å; W62-L65 CarbonylContact O-C 3.05Å; W62-L65 PolarHBondContact O-N 2.9Å; W62-L65 VanDerWaalsContact O-N 3.12Å; W62-Q66 HydrophobicContact CD2-CG 4.2Å; W62-Q66 HydrophobicContact CG-CG 4.48Å; W62-Q66 HydrophobicContact CZ2-CG 4.06Å; W62-Q66 VanDerWaalsContact NE1-CD 3.34Å; W62-Q66 WeakPolarHBondContact O-CG 3.31Å; W62-Q66 PolarHBondContact O-N 3.02Å; W62-M317 HydrophobicContact CB-CE 3.78Å; W62-M317 HydrophobicContact CE3-CE 4.38Å; W62-M317 HydrophobicContact CE3-CG 4.17Å; W62-R320 VanDerWaalsContact CH2-NH1 3.33Å; W62-M370 HydrophobicContact CB-CG 4.45Å; W62-M370 HydrophobicContact CD2-CB 3.92Å; W62-M370 HydrophobicContact CD2-CG 4.22Å; W62-M370 HydrophobicContact CD2-SD 4.44Å; W62-M370 HydrophobicContact CE3-CB 4.41Å; W62-M370 HydrophobicContact CE3-SD 4.27Å; W62-M370 HydrophobicContact CG-CB 4.13Å; W62-M370 HydrophobicContact CG-CG 4.12Å; W62-M370 HydrophobicContact CZ2-CB 4.34Å; W62-M370 WeakPolarHBondContact CZ2-O 3.48Å; W62-M370 PolarHBondContact NE1-O 3.2Å
63G97.3Very high97Very high26 Ų2649.4 Ų49.427%0.26824%0.238SC..Hα-helixtrans-56.9-43.7175.400000111.7N59 Q60 L65 Q66 E67N59-G63 PolarHBondContact O-N 3.5Å; Q60-G63 PolarHBondContact O-N 3.43Å; G63-L65 PolarHBondContact O-N 3.35Å; G63-Q66 PolarHBondContact O-N 3.36Å; G63-E67 PolarHBondContact O-N 3.09Å; G63-E67 VanDerWaalsContact O-N 3.08Å
64K98.1Very high96.7Very high54 Ų5449.2 Ų49.224%0.23524%0.237CC..Hα-helixtrans-63.9-42176-170.968-166.5165.80112.7Q60 L61 W62 Q66 E67 L68 I97 D98 L101Q60-K64 WeakPolarHBondContact O-CB 3.48Å; Q60-K64 PolarHBondContact O-N 2.97Å; L61-K64 PolarHBondContact O-N 3.2Å; W62-K64 VanDerWaalsContact C-N 3.28Å; W62-K64 PolarHBondContact O-N 3.32Å; K64-Q66 VanDerWaalsContact C-N 3.33Å; K64-Q66 PolarHBondContact O-N 3.05Å; K64-E67 IonicContact NZ-OE2 2.69Å; K64-E67 PolarHBondContact NZ-OE2 3.5Å; K64-E67 WeakPolarHBondContact O-CB 3.3Å; K64-E67 PolarHBondContact O-N 3.35Å; K64-L68 WeakPolarHBondContact O-CG 3.43Å; K64-L68 PolarHBondContact O-N 3.48Å; K64-I97 HydrophobicContact CB-CG2 4.31Å; K64-I97 HydrophobicContact CG-CG2 4.22Å; K64-D98 VanDerWaalsContact CE-OD2 3.24Å; K64-D98 WeakPolarHBondContact CE-OD2 3.45Å; K64-D98 HydrophobicContact CG-CB 4.02Å; K64-L101 HydrophobicContact CB-CD1 4.38Å
65L97.6Very high96.4Very high0 Ų052.3 Ų52.30%025%0.252CS..Hα-helixtrans-64.8-37.8175.8-179.956.1000111.8L61 W62 G63 E67 L68 Q69 L116 M317 M321L61-L65 WeakPolarHBondContact O-CB 3.36Å; L61-L65 PolarHBondContact O-N 2.93Å; W62-L65 HydrophobicContact CE3-CB 4.38Å; W62-L65 HydrophobicContact CE3-CD2 3.87Å; W62-L65 HydrophobicContact CE3-CG 4.41Å; W62-L65 HydrophobicContact CZ3-CD2 3.62Å; W62-L65 HydrophobicContact CZ3-CG 4.24Å; W62-L65 CarbonylContact O-C 3.05Å; W62-L65 PolarHBondContact O-N 2.9Å; W62-L65 VanDerWaalsContact O-N 3.12Å; G63-L65 PolarHBondContact O-N 3.35Å; L65-E67 VanDerWaalsContact C-N 3.34Å; L65-E67 PolarHBondContact O-N 2.89Å; L65-L68 PolarHBondContact O-N 3.42Å; L65-Q69 HydrophobicContact CD1-CG 4.3Å; L65-Q69 HydrophobicContact CG-CG 4.45Å; L65-Q69 WeakPolarHBondContact O-CG 3.4Å; L65-Q69 PolarHBondContact O-N 3.08Å; L65-L116 HydrophobicContact CD1-CD1 4.13Å; L65-L116 HydrophobicContact CD1-CD2 4.19Å; L65-L116 HydrophobicContact CD1-CG 4.24Å; L65-M317 HydrophobicContact CD2-CG 3.71Å; L65-M321 HydrophobicContact CD1-CE 4.46Å; L65-M321 HydrophobicContact CD1-CG 3.72Å; L65-M321 HydrophobicContact CD1-SD 4.25Å; L65-M321 HydrophobicContact CD2-CG 3.52Å; L65-M321 HydrophobicContact CD2-SD 3.95Å; L65-M321 HydrophobicContact CG-CG 4.3Å
66Q95.6Very high95.9Very high75 Ų7554.7 Ų54.735%0.3528%0.277SS..Hα-helixtrans-63.1-38.2175-72.7-177.8-64.400112.1W62 G63 K64 L68 Q69 K70 N731W62-Q66 HydrophobicContact CD2-CG 4.2Å; W62-Q66 HydrophobicContact CG-CG 4.48Å; W62-Q66 HydrophobicContact CZ2-CG 4.06Å; W62-Q66 VanDerWaalsContact NE1-CD 3.34Å; W62-Q66 WeakPolarHBondContact O-CG 3.31Å; W62-Q66 PolarHBondContact O-N 3.02Å; G63-Q66 PolarHBondContact O-N 3.36Å; K64-Q66 VanDerWaalsContact C-N 3.33Å; K64-Q66 PolarHBondContact O-N 3.05Å; Q66-L68 VanDerWaalsContact C-N 3.35Å; Q66-Q69 PolarHBondContact O-N 3.35Å; Q66-K70 WeakPolarHBondContact O-CB 3.34Å; Q66-K70 PolarHBondContact O-N 2.91Å; Q66-N731 PolarHBondContact NE2-ND2 3.44Å
67E96.5Very high95.5Very high101 Ų10149.9 Ų49.947%0.47226%0.262SS..Hα-helixtrans-59.6-44.9171.7-67.6178.517400111.7G63 K64 L65 K70 Q71G63-E67 PolarHBondContact O-N 3.09Å; G63-E67 VanDerWaalsContact O-N 3.08Å; K64-E67 IonicContact NZ-OE2 2.69Å; K64-E67 PolarHBondContact NZ-OE2 3.5Å; K64-E67 WeakPolarHBondContact O-CB 3.3Å; K64-E67 PolarHBondContact O-N 3.35Å; L65-E67 VanDerWaalsContact C-N 3.34Å; L65-E67 PolarHBondContact O-N 2.89Å; E67-K70 WeakPolarHBondContact O-CB 3.34Å; E67-K70 PolarHBondContact O-N 3.26Å; E67-Q71 WeakPolarHBondContact O-CG 3.29Å; E67-Q71 PolarHBondContact O-N 3.45Å; E67-Q71 PolarHBondContact O-NE2 3.25Å
68L97.5Very high95.2Very high20 Ų2049.6 Ų49.611%0.10526%0.26CS..Hα-helixtrans-67-39.5178.6-65.2170.3000111.9K64 L65 Q66 K70 Q71 E72 L79 P115 L116K64-L68 WeakPolarHBondContact O-CG 3.43Å; K64-L68 PolarHBondContact O-N 3.48Å; L65-L68 PolarHBondContact O-N 3.42Å; Q66-L68 VanDerWaalsContact C-N 3.35Å; L68-K70 VanDerWaalsContact C-N 3.31Å; L68-K70 PolarHBondContact O-N 2.7Å; L68-Q71 WeakPolarHBondContact O-CB 3.49Å; L68-Q71 PolarHBondContact O-N 3.34Å; L68-E72 PolarHBondContact O-N 2.56Å; L68-L79 HydrophobicContact CB-CD2 4.25Å; L68-L79 HydrophobicContact CD2-CD2 4.09Å; L68-P115 HydrophobicContact CD1-CB 3.87Å; L68-P115 HydrophobicContact CD1-CG 3.43Å; L68-P115 VanDerWaalsContact CD1-CG 3.43Å; L68-L116 HydrophobicContact CB-CD1 3.98Å
69Q95.1Very high95.1Very high10 Ų1051.3 Ų51.35%0.04727%0.269CS..Hα-helixtrans-66.1-33.9174.6-73.3-178.8-5.400111.9L65 Q66 E72 R73 L116 K742L65-Q69 HydrophobicContact CD1-CG 4.3Å; L65-Q69 HydrophobicContact CG-CG 4.45Å; L65-Q69 WeakPolarHBondContact O-CG 3.4Å; L65-Q69 PolarHBondContact O-N 3.08Å; Q66-Q69 PolarHBondContact O-N 3.35Å; Q69-E72 WeakPolarHBondContact O-CB 3.22Å; Q69-E72 PolarHBondContact O-N 3.14Å; Q69-R73 WeakPolarHBondContact O-CG 3.4Å; Q69-R73 PolarHBondContact O-N 3Å; Q69-R73 PolarHBondContact O-NH1 3.39Å; Q69-L116 HydrophobicContact CG-CD1 3.98Å; Q69-K742 VanDerWaalsContact OE1-NZ 3.09Å
70K94.1Very high95Very high113 Ų11349.5 Ų49.549%0.49126%0.26SS..Hα-helixtrans-64.4-45172.4-176.3179175.1179.90111Q66 E67 L68 E72 R73 E74Q66-K70 WeakPolarHBondContact O-CB 3.34Å; Q66-K70 PolarHBondContact O-N 2.91Å; E67-K70 WeakPolarHBondContact O-CB 3.34Å; E67-K70 PolarHBondContact O-N 3.26Å; L68-K70 VanDerWaalsContact C-N 3.31Å; L68-K70 PolarHBondContact O-N 2.7Å; K70-E72 VanDerWaalsContact C-N 3.32Å; K70-E72 PolarHBondContact O-N 3.09Å; K70-R73 PolarHBondContact O-N 3.06Å; K70-E74 WeakPolarHBondContact CE-OE1 3.4Å; K70-E74 WeakPolarHBondContact O-CG 3.22Å; K70-E74 PolarHBondContact O-N 2.92Å
71Q95.9Very high95Very high88 Ų8846.5 Ų46.541%0.41125%0.246SC..Hα-helixtrans-62-39.5174.2-68.3168.148.100111.9E67 L68 R73 E74 N75 L79E67-Q71 WeakPolarHBondContact O-CG 3.29Å; E67-Q71 PolarHBondContact O-N 3.45Å; E67-Q71 PolarHBondContact O-NE2 3.25Å; L68-Q71 WeakPolarHBondContact O-CB 3.49Å; L68-Q71 PolarHBondContact O-N 3.34Å; Q71-R73 VanDerWaalsContact C-N 3.33Å; Q71-R73 PolarHBondContact O-N 2.72Å; Q71-E74 PolarHBondContact O-N 2.63Å; Q71-N75 WeakPolarHBondContact O-CB 3.38Å; Q71-N75 PolarHBondContact O-N 2.83Å; Q71-L79 HydrophobicContact CB-CD1 3.64Å
72E94.6Very high94.9Very high11 Ų1147.3 Ų47.35%0.05125%0.249CC..Hα-helixtrans-56.6-47173.6-178.8174.3-120.900111L68 Q69 K70 N75 G76 G77 V78 L79 R118 K323L68-E72 PolarHBondContact O-N 2.56Å; Q69-E72 WeakPolarHBondContact O-CB 3.22Å; Q69-E72 PolarHBondContact O-N 3.14Å; K70-E72 VanDerWaalsContact C-N 3.32Å; K70-E72 PolarHBondContact O-N 3.09Å; E72-N75 CarbonylContact O-C 3.29Å; E72-N75 PolarHBondContact O-N 3.09Å; E72-G76 PolarHBondContact O-N 3.11Å; E72-G77 VanDerWaalsContact CG-C 3.41Å; E72-G77 WeakPolarHBondContact CG-O 3.35Å; E72-G77 VanDerWaalsContact O-CA 3.28Å; E72-G77 WeakPolarHBondContact O-CA 3.49Å; E72-G77 PolarHBondContact O-N 3.26Å; E72-V78 PolarHBondContact O-N 2.98Å; E72-L79 HydrophobicContact CB-CB 4.12Å; E72-L79 HydrophobicContact CG-CB 4.43Å; E72-R118 IonicContact OE1-NH2 3.06Å; E72-K323 VanDerWaalsContact OE1-CE 3.27Å; E72-K323 WeakPolarHBondContact OE1-CE 3.27Å; E72-K323 IonicContact OE1-NZ 3.7Å; E72-K323 PolarHBondContact OE1-NZ 3.17Å; E72-K323 VanDerWaalsContact OE2-CE 3.3Å; E72-K323 WeakPolarHBondContact OE2-CE 3.31Å; E72-K323 IonicContact OE2-NZ 2.77Å; E72-K323 PolarHBondContact OE2-NZ 3.07Å
73R90.7Very high94.8Very high75 Ų7547.1 Ų47.128%0.28325%0.251SS..Hα-helixtrans-63.5-46176.4-69.7-169.6-57.2-82.36.8112.3Q69 K70 Q71 N75 G76Q69-R73 WeakPolarHBondContact O-CG 3.4Å; Q69-R73 PolarHBondContact O-N 3Å; Q69-R73 PolarHBondContact O-NH1 3.39Å; K70-R73 PolarHBondContact O-N 3.06Å; Q71-R73 VanDerWaalsContact C-N 3.33Å; Q71-R73 PolarHBondContact O-N 2.72Å; R73-N75 PolarHBondContact O-N 3.48Å; R73-G76 PolarHBondContact O-N 3.03Å; R73-G76 VanDerWaalsContact O-N 3.08Å
74E91.8Very high94.7Very high140 Ų14050.5 Ų50.565%0.65426%0.263SS*.Hα-helixtrans-61.7-27.2177.1-71.4172.4179.100112.4K70 Q71 G76K70-E74 WeakPolarHBondContact CE-OE1 3.4Å; K70-E74 WeakPolarHBondContact O-CG 3.22Å; K70-E74 PolarHBondContact O-N 2.92Å; Q71-E74 PolarHBondContact O-N 2.63Å; E74-G76 VanDerWaalsContact C-N 3.34Å
75N91.7Very high94.6Very high89 Ų8950.2 Ų50.248%0.47627%0.265SS..THydrogen-bonded Turntrans-92.821.1175.8-158.134.8000114Q71 E72 R73 V78Q71-N75 WeakPolarHBondContact O-CB 3.38Å; Q71-N75 PolarHBondContact O-N 2.83Å; E72-N75 CarbonylContact O-C 3.29Å; E72-N75 PolarHBondContact O-N 3.09Å; R73-N75 PolarHBondContact O-N 3.48Å; N75-V78 WeakPolarHBondContact CB-O 3.49Å; N75-V78 PolarHBondContact ND2-O 2.84Å
76G87.7Confident94.6Very high55 Ų5551.5 Ų51.557%0.56727%0.273SS*.THydrogen-bonded Turntrans75.527.5175.800000114.4E72 R73 E74E72-G76 PolarHBondContact O-N 3.11Å; R73-G76 PolarHBondContact O-N 3.03Å; R73-G76 VanDerWaalsContact O-N 3.08Å; E74-G76 VanDerWaalsContact C-N 3.34Å
77G89.4Confident94.7Very high28 Ų2848.3 Ų48.329%0.28926%0.26SS..THydrogen-bonded Turntrans94.11.4173.300000115.2E72 R118E72-G77 VanDerWaalsContact CG-C 3.41Å; E72-G77 WeakPolarHBondContact CG-O 3.35Å; E72-G77 VanDerWaalsContact O-CA 3.28Å; E72-G77 WeakPolarHBondContact O-CA 3.49Å; E72-G77 PolarHBondContact O-N 3.26Å; G77-R118 PolarHBondContact O-NH2 3.27Å
78V93.7Very high94.8Very high0 Ų044.7 Ų44.70%025%0.247CC..  trans-132.9119.3177.3178.80000109.7E72 N75 M81 R118 Y136E72-V78 PolarHBondContact O-N 2.98Å; N75-V78 WeakPolarHBondContact CB-O 3.49Å; N75-V78 PolarHBondContact ND2-O 2.84Å; V78-M81 HydrophobicContact CG1-CG 3.6Å; V78-M81 HydrophobicContact CG1-SD 4.15Å; V78-R118 HydrophobicContact CG1-CG 4.4Å; V78-Y136 HydrophobicContact CB-CD1 3.81Å; V78-Y136 HydrophobicContact CB-CD2 4.46Å; V78-Y136 HydrophobicContact CB-CE1 3.78Å; V78-Y136 HydrophobicContact CB-CE2 4.46Å; V78-Y136 HydrophobicContact CB-CG 4.17Å; V78-Y136 HydrophobicContact CG1-CG 4.43Å; V78-Y136 HydrophobicContact CG2-CD1 3.81Å; V78-Y136 HydrophobicContact CG2-CD2 3.98Å; V78-Y136 HydrophobicContact CG2-CE1 3.33Å; V78-Y136 HydrophobicContact CG2-CE2 3.55Å; V78-Y136 HydrophobicContact CG2-CG 4.12Å
79L96.6Very high94.8Very high36 Ų3643.8 Ų43.819%0.18824%0.242CC..SBendtrans-74.5-52.8179.2-174.865.1000112.3L68 Q71 E72 L116L68-L79 HydrophobicContact CB-CD2 4.25Å; L68-L79 HydrophobicContact CD2-CD2 4.09Å; Q71-L79 HydrophobicContact CB-CD1 3.64Å; E72-L79 HydrophobicContact CB-CB 4.12Å; E72-L79 HydrophobicContact CG-CB 4.43Å; L79-L116 HydrophobicContact CB-CB 4.25Å; L79-L116 HydrophobicContact CD2-CB 4.03Å; L79-L116 HydrophobicContact CD2-CD1 4.32Å
80D97.1Very high94.9Very high33 Ų3346.3 Ų46.318%0.17626%0.256CS..EExtended strand (participates in β ladder)trans-152.5156.5-175.4-165.71000109.9K114 K117 R118 Y138D80-K114 IonicContact OD2-NZ 3.83Å; D80-K114 PolarHBondContact OD2-NZ 2.94Å; D80-K117 HydrophobicContact CB-CB 3.91Å; D80-K117 HydrophobicContact CB-CG 3.95Å; D80-K117 WeakPolarHBondContact O-CA 3.25Å; D80-R118 PolarHBondContact O-N 2.86Å; D80-Y138 WeakPolarHBondContact CA-OH 3.41Å; D80-Y138 PolarHBondContact OD1-OH 3.33Å
81M97.2Very high95Very high9 Ų942.7 Ų42.74%0.04425%0.247CC..EExtended strand (participates in β ladder)trans-135.4142177.8-63.3-169.17200112.1V78 R118 L133 Y136 Y138 A325V78-M81 HydrophobicContact CG1-CG 3.6Å; V78-M81 HydrophobicContact CG1-SD 4.15Å; M81-R118 HydrophobicContact CG-CB 4.41Å; M81-L133 HydrophobicContact CB-CD2 3.9Å; M81-L133 HydrophobicContact CE-CD2 3.77Å; M81-L133 HydrophobicContact CE-CG 4.3Å; M81-L133 HydrophobicContact SD-CD2 4.21Å; M81-Y136 HydrophobicContact SD-CD2 3.7Å; M81-Y136 HydrophobicContact SD-CG 4.09Å; M81-Y138 HydrophobicContact CB-CD1 4.16Å; M81-Y138 HydrophobicContact CB-CD2 3.95Å; M81-Y138 HydrophobicContact CB-CE1 4.05Å; M81-Y138 HydrophobicContact CB-CE2 3.86Å; M81-Y138 HydrophobicContact CB-CG 4.13Å; M81-Y138 HydrophobicContact CG-CD2 4.14Å; M81-Y138 HydrophobicContact CG-CE2 3.92Å; M81-Y138 PolarHBondContact N-OH 2.73Å; M81-Y138 HydrophobicContact SD-CD2 4.06Å; M81-Y138 HydrophobicContact SD-CE2 4.3Å; M81-A325 HydrophobicContact CE-CB 3.54Å
82E96.8Very high95.1Very high16 Ų1639.5 Ų39.58%0.07523%0.232CC..EExtended strand (participates in β ladder)trans-84.3137.8168.4-176.556.5-105.700111.1D84 V85 Y92 K117 R118 F120 L133E82-D84 WeakPolarHBondContact OE1-CA 3.39Å; E82-D84 PolarHBondContact OE1-N 2.89Å; E82-V85 HydrophobicContact CG-CB 3.88Å; E82-V85 WeakPolarHBondContact CG-O 3.32Å; E82-V85 PolarHBondContact OE1-N 3.34Å; E82-Y92 HydrophobicContact CG-CE1 4.2Å; E82-Y92 WeakPolarHBondContact CG-OH 3.4Å; E82-K117 WeakPolarHBondContact OE2-CE 3.39Å; E82-K117 IonicContact OE2-NZ 2.77Å; E82-K117 PolarHBondContact OE2-NZ 2.99Å; E82-R118 PolarHBondContact N-O 2.7Å; E82-F120 HydrophobicContact CB-CB 4.37Å; E82-F120 HydrophobicContact CG-CB 4.25Å; E82-F120 WeakPolarHBondContact O-CB 3.39Å; E82-L133 WeakPolarHBondContact O-CD2 3.35Å
83A96Very high95.1Very high11 Ų1141.2 Ų41.29%0.09125%0.252CS..EExtended strand (participates in β ladder)trans-128.6-17.1175.800000113.4L133 N141A83-L133 HydrophobicContact CB-CD1 3.95Å; A83-L133 HydrophobicContact CB-CD2 4.05Å; A83-N141 WeakPolarHBondContact O-CB 3.39Å
84D95.4Very high95.4Very high97 Ų9739.2 Ų39.252%0.51925%0.251SS..EExtended strand (participates in β ladder)trans-111.8-12.1-168.6-69.5-45.5000113.6E82 N141 Y144E82-D84 WeakPolarHBondContact OE1-CA 3.39Å; E82-D84 PolarHBondContact OE1-N 2.89Å; D84-N141 PolarHBondContact OD1-ND2 2.88Å; D84-Y144 WeakPolarHBondContact O-CE2 3.17Å; D84-Y144 PolarHBondContact O-OH 3.4Å
85V96.8Very high95.6Very high47 Ų4732.6 Ų32.629%0.28522%0.221SC..EExtended strand (participates in β ladder)trans-120.6116.9177.8-176.20000110.6E82 S87 A91 Y92 F120E82-V85 HydrophobicContact CG-CB 3.88Å; E82-V85 WeakPolarHBondContact CG-O 3.32Å; E82-V85 PolarHBondContact OE1-N 3.34Å; V85-S87 PolarHBondContact O-N 3.13Å; V85-A91 HydrophobicContact CG1-CB 4Å; V85-Y92 HydrophobicContact CB-CE1 3.99Å; V85-Y92 HydrophobicContact CG1-CD1 4.42Å; V85-Y92 HydrophobicContact CG1-CE1 3.94Å; V85-F120 WeakPolarHBondContact O-CB 3.35Å
86V97.6Very high96Very high27 Ų2730.5 Ų30.516%0.16421%0.207CC..EExtended strand (participates in β ladder)trans-69.5123.2169.4176.10000108.7A91 F120 P122 Y123 Y144 F148V86-A91 WeakPolarHBondContact O-CB 3.47Å; V86-F120 HydrophobicContact CG2-CD1 4.11Å; V86-F120 HydrophobicContact CG2-CE1 4.28Å; V86-P122 HydrophobicContact CG1-CG 4.04Å; V86-P122 HydrophobicContact CG2-CG 4.11Å; V86-Y123 HydrophobicContact CG1-CD2 4.4Å; V86-Y123 HydrophobicContact CG1-CE2 3.66Å; V86-Y144 HydrophobicContact CG2-CD1 3.61Å; V86-Y144 HydrophobicContact CG2-CD2 4.34Å; V86-Y144 HydrophobicContact CG2-CE1 3.47Å; V86-Y144 VanDerWaalsContact CG2-CE1 3.47Å; V86-Y144 HydrophobicContact CG2-CE2 4.22Å; V86-Y144 HydrophobicContact CG2-CG 4.09Å; V86-F148 HydrophobicContact CG1-CZ 4.29Å; V86-F148 HydrophobicContact CG2-CE2 3.94Å; V86-F148 HydrophobicContact CG2-CZ 4.33Å
87S97.5Very high96.5Very high9 Ų928.1 Ų28.16%0.06318%0.181CC..  trans-64.4138.9-176-156.40000112.7V85 F120 K274V85-S87 PolarHBondContact O-N 3.13Å; S87-F120 WeakPolarHBondContact CB-O 3.22Å; S87-F120 PolarHBondContact N-O 2.96Å; S87-K274 VanDerWaalsContact CB-O 3.28Å; S87-K274 WeakPolarHBondContact CB-O 3.47Å; S87-K274 PolarHBondContact OG-O 2.82Å
88A97.1Very high96.8Very high25 Ų2528.6 Ų28.621%0.20718%0.177CC..  trans-155.8166.316700000108.1N90 A91A88-N90 PolarHBondContact O-N 3.27Å; A88-N90 VanDerWaalsContact O-N 3.14Å; A88-A91 HydrophobicContact CB-CB 4Å; A88-A91 WeakPolarHBondContact O-CB 3.36Å; A88-A91 PolarHBondContact O-N 3.38Å; A88-A91 VanDerWaalsContact O-N 3.1Å
89A97.3Very high97Very high0 Ų033.8 Ų33.80%020%0.201CC..THydrogen-bonded Turntrans-53.4-39.6-179.400000112.6R239 M243 A271 K274 E275A89-R239 HydrophobicContact CB-CB 4.12Å; A89-M243 HydrophobicContact CB-SD 4.22Å; A89-M243 VanDerWaalsContact O-CB 3.32Å; A89-M243 WeakPolarHBondContact O-CB 3.29Å; A89-M243 WeakPolarHBondContact O-CG 3.4Å; A89-A271 HydrophobicContact CB-CB 3.93Å; A89-K274 WeakPolarHBondContact O-CD 3.48Å; A89-E275 HydrophobicContact CB-CG 4.13Å; A89-E275 VanDerWaalsContact CB-OE1 3.3Å; A89-E275 WeakPolarHBondContact CB-OE1 3.43Å; A89-E275 PolarHBondContact N-OE1 3.41Å
90N97.1Very high97Very high64 Ų6439.3 Ų39.334%0.34223%0.229SC..THydrogen-bonded Turntrans-105.417.5-178.966.9-15.7000114.1A88 E242A88-N90 PolarHBondContact O-N 3.27Å; A88-N90 VanDerWaalsContact O-N 3.14Å; N90-E242 HydrophobicContact CB-CB 4.19Å; N90-E242 PolarHBondContact ND2-OE2 3.46Å
91A97.4Very high97Very high37 Ų3739.3 Ų39.331%0.30623%0.229SC..SBendtrans-76.2-26.6-176.100000114.1V85 V86 A88V85-A91 HydrophobicContact CG1-CB 4Å; V86-A91 WeakPolarHBondContact O-CB 3.47Å; A88-A91 HydrophobicContact CB-CB 4Å; A88-A91 WeakPolarHBondContact O-CB 3.36Å; A88-A91 PolarHBondContact O-N 3.38Å; A88-A91 VanDerWaalsContact O-N 3.1Å
92Y96.8Very high97Very high21 Ų2142.3 Ų42.38%0.08224%0.242CC..SBendtrans-112.9156-179.4-54.7-91000110.2E82 V85 Q111 T112E82-Y92 HydrophobicContact CG-CE1 4.2Å; E82-Y92 WeakPolarHBondContact CG-OH 3.4Å; V85-Y92 HydrophobicContact CB-CE1 3.99Å; V85-Y92 HydrophobicContact CG1-CD1 4.42Å; V85-Y92 HydrophobicContact CG1-CE1 3.94Å; Y92-Q111 WeakPolarHBondContact CD2-O 3.32Å; Y92-T112 HydrophobicContact CE1-CG2 4.04Å; Y92-T112 HydrophobicContact CE2-CG2 4.16Å
93G94.7Very high97Very high47 Ų4748.5 Ų48.549%0.48528%0.275SS..  trans-71.2-172165.300000112.2G95G93-G95 PolarHBondContact O-N 2.62Å
94A97.1Very high97.1Very high32 Ų3252.2 Ų52.226%0.26429%0.291SS..  trans-67.8129.5171.200000111Y96 A246 Y247A94-Y96 HydrophobicContact CB-CE2 4.02Å; A94-A246 WeakPolarHBondContact CB-O 3.23Å; A94-Y247 VanDerWaalsContact CA-CZ 3.49Å; A94-Y247 HydrophobicContact CB-CD1 3.6Å; A94-Y247 HydrophobicContact CB-CD2 4.15Å; A94-Y247 HydrophobicContact CB-CE1 3.58Å; A94-Y247 HydrophobicContact CB-CE2 4.13Å; A94-Y247 HydrophobicContact CB-CG 3.9Å
95G97.5Very high97.3Very high1 Ų148 Ų481%0.0127%0.268CS..  trans-120147.7168.100000111.7G93 I110 Y247G93-G95 PolarHBondContact O-N 2.62Å; G95-I110 WeakPolarHBondContact O-CG1 3.41Å; G95-Y247 PolarHBondContact N-OH 3.14Å; G95-Y247 VanDerWaalsContact O-CE1 3.24Å; G95-Y247 WeakPolarHBondContact O-CE1 3.48Å; G95-Y247 PolarHBondContact O-OH 2.94Å
96Y98.4Very high97.3Very high46 Ų4646.1 Ų46.118%0.1826%0.257CS..  trans-126.1163.2-174.5-61.8-79.1000110.3A94 D98 E99 K102 E105 V108 P115 Y247A94-Y96 HydrophobicContact CB-CE2 4.02Å; Y96-D98 VanDerWaalsContact C-N 3.3Å; Y96-E99 WeakPolarHBondContact CD2-OE1 3.34Å; Y96-K102 HydrophobicContact CD1-CB 3.59Å; Y96-K102 HydrophobicContact CD2-CB 4.13Å; Y96-K102 HydrophobicContact CD2-CD 4.21Å; Y96-K102 HydrophobicContact CE1-CB 4.05Å; Y96-K102 HydrophobicContact CE2-CD 4.13Å; Y96-K102 HydrophobicContact CG-CB 3.63Å; Y96-E105 WeakPolarHBondContact CA-OE1 3.45Å; Y96-E105 VanDerWaalsContact CB-OE1 3.25Å; Y96-E105 WeakPolarHBondContact CB-OE1 3.24Å; Y96-V108 HydrophobicContact CD1-CG1 4.25Å; Y96-V108 HydrophobicContact CE1-CB 4.26Å; Y96-V108 HydrophobicContact CE1-CG1 3.91Å; Y96-P115 WeakPolarHBondContact O-CD 3.38Å; Y96-Y247 HydrophobicContact CE1-CD1 4.25Å; Y96-Y247 HydrophobicContact CE1-CE1 4.35Å
97I98.2Very high97.4Very high5 Ų544.8 Ų44.83%0.02625%0.249CC..SBendtrans-61.7-44.2175.1-67.8169.1000109.8L61 K64 E105 M317 M321L61-I97 HydrophobicContact CB-CD1 4.27Å; L61-I97 HydrophobicContact CD2-CB 4.24Å; L61-I97 HydrophobicContact CD2-CD1 4.18Å; L61-I97 HydrophobicContact CD2-CG2 4.41Å; K64-I97 HydrophobicContact CB-CG2 4.31Å; K64-I97 HydrophobicContact CG-CG2 4.22Å; I97-E105 PolarHBondContact N-OE1 3.17Å; I97-M317 HydrophobicContact CD1-CG 4.2Å; I97-M317 HydrophobicContact CD1-SD 3.48Å; I97-M317 WeakPolarHBondContact CD1-SD 3.11Å; I97-M321 HydrophobicContact CD1-SD 4Å; I97-M321 HydrophobicContact CG1-CE 3.79Å; I97-M321 HydrophobicContact CG1-SD 3.76Å
98D97.6Very high97.5Very high38 Ų3844.9 Ų44.920%0.20325%0.25CC..  trans-151.4133.4174.2-174-71.2000108.8K64 Y96 I100 L101 K102K64-D98 VanDerWaalsContact CE-OD2 3.24Å; K64-D98 WeakPolarHBondContact CE-OD2 3.45Å; K64-D98 HydrophobicContact CG-CB 4.02Å; Y96-D98 VanDerWaalsContact C-N 3.3Å; D98-I100 PolarHBondContact O-N 3.1Å; D98-I100 WeakPolarHBondContact OD1-CA 3.5Å; D98-I100 WeakPolarHBondContact OD1-CB 3.31Å; D98-I100 PolarHBondContact OD1-N 2.74Å; D98-L101 HydrophobicContact CB-CB 4.2Å; D98-L101 HydrophobicContact CB-CD1 4.33Å; D98-L101 HydrophobicContact CB-CG 4.29Å; D98-L101 CarbonylContact O-C 3.54Å; D98-L101 PolarHBondContact O-N 3.3Å; D98-L101 VanDerWaalsContact O-N 3.12Å; D98-L101 PolarHBondContact OD1-N 2.88Å; D98-K102 PolarHBondContact O-N 3.32Å
99E96.2Very high97.5Very high109 Ų10943.7 Ų43.751%0.50924%0.24SC..THydrogen-bonded Turntrans-64.6-25.6-177.5-90-66.8167.100113.6Y96 K102Y96-E99 WeakPolarHBondContact CD2-OE1 3.34Å; E99-K102 WeakPolarHBondContact OE2-CD 3.43Å; E99-K102 IonicContact OE2-NZ 3.91Å; E99-K102 PolarHBondContact OE2-NZ 2.85Å
100I97.3Very high97.6Very high152 Ų15244 Ų4478%0.77924%0.242SC*.THydrogen-bonded Turntrans-76-34.4176.1-56.8174.8000110.1D98D98-I100 PolarHBondContact O-N 3.1Å; D98-I100 WeakPolarHBondContact OD1-CA 3.5Å; D98-I100 WeakPolarHBondContact OD1-CB 3.31Å; D98-I100 PolarHBondContact OD1-N 2.74Å
101L97.1Very high97.6Very high33 Ų3341.5 Ų41.517%0.17323%0.228CC..THydrogen-bonded Turntrans-96.26.1-177.2-57.6178.1000113.9Q60 L61 K64 D98 D103 E104Q60-L101 HydrophobicContact CB-CD1 4.28Å; L61-L101 HydrophobicContact CD2-CB 3.79Å; L61-L101 HydrophobicContact CD2-CD1 4.3Å; K64-L101 HydrophobicContact CB-CD1 4.38Å; D98-L101 HydrophobicContact CB-CB 4.2Å; D98-L101 HydrophobicContact CB-CD1 4.33Å; D98-L101 HydrophobicContact CB-CG 4.29Å; D98-L101 CarbonylContact O-C 3.54Å; D98-L101 PolarHBondContact O-N 3.3Å; D98-L101 VanDerWaalsContact O-N 3.12Å; D98-L101 PolarHBondContact OD1-N 2.88Å; L101-D103 PolarHBondContact O-N 3.4Å; L101-D103 VanDerWaalsContact O-N 3.11Å; L101-E104 HydrophobicContact CD2-CG 4.47Å; L101-E104 WeakPolarHBondContact O-CA 3.5Å; L101-E104 VanDerWaalsContact O-CB 3.26Å; L101-E104 WeakPolarHBondContact O-CB 3.48Å; L101-E104 PolarHBondContact O-N 3.22Å
102K96.9Very high97.7Very high72 Ų7239.8 Ų39.831%0.31321%0.213SC..G310 helixtrans-58.7-30.2-173.871.5-179.4168.9-158.90114.6Y96 D98 E99 E104 E105Y96-K102 HydrophobicContact CD1-CB 3.59Å; Y96-K102 HydrophobicContact CD2-CB 4.13Å; Y96-K102 HydrophobicContact CD2-CD 4.21Å; Y96-K102 HydrophobicContact CE1-CB 4.05Å; Y96-K102 HydrophobicContact CE2-CD 4.13Å; Y96-K102 HydrophobicContact CG-CB 3.63Å; D98-K102 PolarHBondContact O-N 3.32Å; E99-K102 WeakPolarHBondContact OE2-CD 3.43Å; E99-K102 IonicContact OE2-NZ 3.91Å; E99-K102 PolarHBondContact OE2-NZ 2.85Å; K102-E104 PolarHBondContact O-N 2.96Å; K102-E105 WeakPolarHBondContact O-CB 3.36Å; K102-E105 PolarHBondContact O-N 3.46Å
103D97.2Very high97.7Very high146 Ų14642.2 Ų42.278%0.78123%0.228SC*.G310 helixtrans-75.8-16.3179.4-66.5-34.8000111.8L101L101-D103 PolarHBondContact O-N 3.4Å; L101-D103 VanDerWaalsContact O-N 3.11Å
104E98Very high97.8Very high89 Ų8944.8 Ų44.842%0.41623%0.225SC..G310 helixtrans-81.4-17172.6-55.1-59.2154.800112A57 L61 L101 K102 A106 H314A57-E104 HydrophobicContact CB-CB 3.99Å; L61-E104 HydrophobicContact CD1-CB 4.31Å; L61-E104 HydrophobicContact CG-CB 4.48Å; L101-E104 HydrophobicContact CD2-CG 4.47Å; L101-E104 WeakPolarHBondContact O-CA 3.5Å; L101-E104 VanDerWaalsContact O-CB 3.26Å; L101-E104 WeakPolarHBondContact O-CB 3.48Å; L101-E104 PolarHBondContact O-N 3.22Å; K102-E104 PolarHBondContact O-N 2.96Å; E104-A106 PolarHBondContact O-N 3.42Å; E104-H314 PolarHBondContact O-CE1 3.3Å
105E98.6Very high97.8Very high7 Ų744 Ų443%0.03322%0.218CC..  trans-72.795.8179.2-66.8-171.3-134.100111.6L61 Y96 I97 K102 I107 V108 K318L61-E105 HydrophobicContact CD1-CB 4.48Å; L61-E105 HydrophobicContact CD1-CG 3.87Å; L61-E105 HydrophobicContact CD2-CG 3.73Å; L61-E105 HydrophobicContact CG-CG 4.48Å; Y96-E105 WeakPolarHBondContact CA-OE1 3.45Å; Y96-E105 VanDerWaalsContact CB-OE1 3.25Å; Y96-E105 WeakPolarHBondContact CB-OE1 3.24Å; I97-E105 PolarHBondContact N-OE1 3.17Å; K102-E105 WeakPolarHBondContact O-CB 3.36Å; K102-E105 PolarHBondContact O-N 3.46Å; E105-I107 PolarHBondContact O-N 2.98Å; E105-V108 HydrophobicContact CB-CG1 3.75Å; E105-K318 WeakPolarHBondContact OE2-CE 3.17Å; E105-K318 IonicContact OE2-NZ 2.88Å; E105-K318 PolarHBondContact OE2-NZ 3.32Å
106A98.6Very high97.8Very high8 Ų844.3 Ų44.37%0.06622%0.219CC..SBendtrans-58.9-31.4171.500000113.5E104 K259 E310 L311 H314E104-A106 PolarHBondContact O-N 3.42Å; A106-K259 WeakPolarHBondContact O-CE 3.32Å; A106-E310 HydrophobicContact CB-CG 4.15Å; A106-L311 HydrophobicContact CB-CD2 4.02Å; A106-H314 VanDerWaalsContact CB-ND1 3.26Å; A106-H314 WeakPolarHBondContact CB-ND1 3.24Å; A106-H314 PolarHBondContact N-ND1 3.11Å
107I98.9Very high97.8Very high0 Ų043 Ų430%021%0.214CC..SBendtrans-127.3125.1173.2-57.3-62.5000108.7E105 V262 Q263 Y266 L311 H314 K318E105-I107 PolarHBondContact O-N 2.98Å; I107-V262 HydrophobicContact CD1-CB 3.76Å; I107-V262 HydrophobicContact CD1-CG1 3.41Å; I107-V262 VanDerWaalsContact CD1-CG1 3.41Å; I107-V262 HydrophobicContact CG1-CG1 3.75Å; I107-Q263 HydrophobicContact CD1-CB 4.04Å; I107-Y266 HydrophobicContact CG2-CD1 3.96Å; I107-Y266 HydrophobicContact CG2-CG 4.34Å; I107-L311 HydrophobicContact CD1-CD2 3.98Å; I107-L311 HydrophobicContact CG1-CD2 4.36Å; I107-H314 HydrophobicContact CB-CB 3.98Å; I107-H314 HydrophobicContact CG1-CB 4.12Å; I107-K318 WeakPolarHBondContact O-CE 3.36Å; I107-K318 PolarHBondContact O-NZ 2.99Å
108V98.8Very high97.8Very high11 Ų1143 Ų437%0.06721%0.214CC..  trans-113.3162.8-174.6-59.40000112.2Y96 E105 Y247 F249 Q263 Y266 F267Y96-V108 HydrophobicContact CD1-CG1 4.25Å; Y96-V108 HydrophobicContact CE1-CB 4.26Å; Y96-V108 HydrophobicContact CE1-CG1 3.91Å; E105-V108 HydrophobicContact CB-CG1 3.75Å; V108-Y247 HydrophobicContact CB-CD1 3.9Å; V108-Y247 HydrophobicContact CB-CE1 4.22Å; V108-Y247 HydrophobicContact CG2-CD1 3.59Å; V108-Y247 HydrophobicContact CG2-CE1 4.34Å; V108-Y247 HydrophobicContact CG2-CG 4.09Å; V108-F249 HydrophobicContact CG2-CD2 4.3Å; V108-F249 HydrophobicContact CG2-CE2 3.53Å; V108-F249 HydrophobicContact CG2-CZ 4.29Å; V108-Q263 PolarHBondContact O-NE2 2.99Å; V108-Y266 WeakPolarHBondContact O-CD1 3.4Å; V108-Y266 WeakPolarHBondContact O-CE1 3.48Å; V108-F267 HydrophobicContact CG2-CZ 4.24Å
109G98.5Very high97.8Very high0 Ų041.4 Ų41.40%021%0.206CC..  trans122.4131.3178.100000112.2Y247 Y266 K318G109-Y247 VanDerWaalsContact CA-CZ 3.47Å; G109-Y247 WeakPolarHBondContact CA-OH 3.36Å; G109-Y266 WeakPolarHBondContact O-CE1 3.46Å; G109-Y266 PolarHBondContact O-OH 3.5Å; G109-K318 VanDerWaalsContact O-CD 3.26Å; G109-K318 WeakPolarHBondContact O-CD 3.45Å; G109-K318 WeakPolarHBondContact O-CE 3.09Å
110I98.4Very high97.8Very high7 Ų736.6 Ų36.64%0.03618%0.184CC..  trans-143.8161.3172.865.1-175.8000109.9G95 T112 Y247 K274 K318 M321G95-I110 WeakPolarHBondContact O-CG1 3.41Å; I110-T112 VanDerWaalsContact C-N 3.34Å; I110-T112 WeakPolarHBondContact CG1-O 3.31Å; I110-T112 PolarHBondContact O-N 3.4Å; I110-Y247 PolarHBondContact N-OH 3.3Å; I110-Y247 VanDerWaalsContact N-OH 3.1Å; I110-K274 WeakPolarHBondContact O-CE 3.23Å; I110-K274 PolarHBondContact O-NZ 2.79Å; I110-K318 HydrophobicContact CG2-CD 4.24Å; I110-M321 HydrophobicContact CG2-CE 3.64Å
111Q98.3Very high97.8Very high11 Ų1130 Ų305%0.05115%0.149CC..SBendtrans-63.8-32.4-171.7-77.7173.5-80.500114.4Y92 I273 K274 V322 K323Y92-Q111 WeakPolarHBondContact CD2-O 3.32Å; Q111-I273 HydrophobicContact CG-CB 4.33Å; Q111-I273 HydrophobicContact CG-CD1 3.61Å; Q111-I273 HydrophobicContact CG-CG1 3.8Å; Q111-I273 PolarHBondContact NE2-O 3.36Å; Q111-K274 WeakPolarHBondContact O-CG 3.5Å; Q111-K274 PolarHBondContact O-NZ 2.97Å; Q111-V322 VanDerWaalsContact OE1-CA 3.31Å; Q111-K323 PolarHBondContact NE2-O 3.44Å; Q111-K323 VanDerWaalsContact NE2-O 3.08Å; Q111-K323 PolarHBondContact OE1-O 3.22Å; Q111-K323 VanDerWaalsContact OE1-O 3.13Å
112T98.2Very high97.8Very high1 Ų128.4 Ų28.41%0.00614%0.141CC..SBendtrans-123.4-148.4-179.961.80000110.1Y92 I110 K114 K117 A119Y92-T112 HydrophobicContact CE1-CG2 4.04Å; Y92-T112 HydrophobicContact CE2-CG2 4.16Å; I110-T112 VanDerWaalsContact C-N 3.34Å; I110-T112 WeakPolarHBondContact CG1-O 3.31Å; I110-T112 PolarHBondContact O-N 3.4Å; T112-K114 PolarHBondContact OG1-N 2.88Å; T112-K114 PolarHBondContact OG1-O 3.29Å; T112-K114 VanDerWaalsContact OG1-O 3.05Å; T112-K117 HydrophobicContact CG2-CG 4.36Å; T112-K117 WeakPolarHBondContact CG2-O 3.49Å; T112-K117 WeakPolarHBondContact OG1-CB 3.34Å; T112-K117 PolarHBondContact OG1-O 3.01Å; T112-A119 HydrophobicContact CG2-CB 3.79Å
113D96.4Very high97.9Very high71 Ų7129 Ų2938%0.3814%0.142SC..SBendtrans-89.1-10.6171.860.6-44000113.3K117D113-K117 WeakPolarHBondContact OD1-CD 3.22Å; D113-K117 IonicContact OD1-NZ 3.4Å; D113-K117 PolarHBondContact OD1-NZ 3.16Å; D113-K117 IonicContact OD2-NZ 3.99Å
114K97Very high97.8Very high101 Ų10122.1 Ų22.144%0.43911%0.106SC..SBendtrans-137.4150.2-177.3-66.7-178.1-166.4168.20112.6D80 T112 K117D80-K114 IonicContact OD2-NZ 3.83Å; D80-K114 PolarHBondContact OD2-NZ 2.94Å; T112-K114 PolarHBondContact OG1-N 2.88Å; T112-K114 PolarHBondContact OG1-O 3.29Å; T112-K114 VanDerWaalsContact OG1-O 3.05Å; K114-K117 HydrophobicContact CB-CB 4.04Å; K114-K117 HydrophobicContact CB-CD 4.31Å; K114-K117 PolarHBondContact O-N 3.39Å
115P97.6Very high97.8Very high17 Ų1718.1 Ų18.111%0.119%0.088CC..THydrogen-bonded Turntrans-62.4140176.928.7-37.4000110.6L68 Y96 K117 M321L68-P115 HydrophobicContact CD1-CB 3.87Å; L68-P115 HydrophobicContact CD1-CG 3.43Å; L68-P115 VanDerWaalsContact CD1-CG 3.43Å; Y96-P115 WeakPolarHBondContact O-CD 3.38Å; P115-K117 PolarHBondContact O-N 2.85Å; P115-M321 HydrophobicContact CB-CE 3.38Å
116L97.7Very high97.7Very high6 Ų618 Ų183%0.0319%0.088CC..THydrogen-bonded Turntrans60.62177.9-47.8179.5000116.3L65 L68 Q69 L79 R118 M321 K323L65-L116 HydrophobicContact CD1-CD1 4.13Å; L65-L116 HydrophobicContact CD1-CD2 4.19Å; L65-L116 HydrophobicContact CD1-CG 4.24Å; L68-L116 HydrophobicContact CB-CD1 3.98Å; Q69-L116 HydrophobicContact CG-CD1 3.98Å; L79-L116 HydrophobicContact CB-CB 4.25Å; L79-L116 HydrophobicContact CD2-CB 4.03Å; L79-L116 HydrophobicContact CD2-CD1 4.32Å; L116-R118 PolarHBondContact O-N 3.15Å; L116-M321 HydrophobicContact CD2-CB 4.11Å; L116-M321 HydrophobicContact CD2-CG 4.24Å; L116-K323 HydrophobicContact CD2-CG 4.19Å
117K97.9Very high97.6Very high18 Ų1824 Ų248%0.07811%0.109CC..EExtended strand (participates in β ladder)trans-72.5121.6173.9175.1-177.5175.1-165.80110D80 E82 T112 D113 K114 P115D80-K117 HydrophobicContact CB-CB 3.91Å; D80-K117 HydrophobicContact CB-CG 3.95Å; D80-K117 WeakPolarHBondContact O-CA 3.25Å; E82-K117 WeakPolarHBondContact OE2-CE 3.39Å; E82-K117 IonicContact OE2-NZ 2.77Å; E82-K117 PolarHBondContact OE2-NZ 2.99Å; T112-K117 HydrophobicContact CG2-CG 4.36Å; T112-K117 WeakPolarHBondContact CG2-O 3.49Å; T112-K117 WeakPolarHBondContact OG1-CB 3.34Å; T112-K117 PolarHBondContact OG1-O 3.01Å; D113-K117 WeakPolarHBondContact OD1-CD 3.22Å; D113-K117 IonicContact OD1-NZ 3.4Å; D113-K117 PolarHBondContact OD1-NZ 3.16Å; D113-K117 IonicContact OD2-NZ 3.99Å; K114-K117 HydrophobicContact CB-CB 4.04Å; K114-K117 HydrophobicContact CB-CD 4.31Å; K114-K117 PolarHBondContact O-N 3.39Å; P115-K117 PolarHBondContact O-N 2.85Å
118R97.7Very high97.4Very high6 Ų624.6 Ų24.62%0.02311%0.112CC..EExtended strand (participates in β ladder)trans-79.8126.2-175.4-56.8-172.9-178.6-134.13.6110.7E72 G77 V78 D80 M81 E82 L116 K323 F324 A325 D337E72-R118 IonicContact OE1-NH2 3.06Å; G77-R118 PolarHBondContact O-NH2 3.27Å; V78-R118 HydrophobicContact CG1-CG 4.4Å; D80-R118 PolarHBondContact O-N 2.86Å; M81-R118 HydrophobicContact CG-CB 4.41Å; E82-R118 PolarHBondContact N-O 2.7Å; L116-R118 PolarHBondContact O-N 3.15Å; R118-K323 HydrophobicContact CG-CB 3.96Å; R118-F324 WeakPolarHBondContact CD-O 3.47Å; R118-F324 PolarHBondContact NH1-O 3.06Å; R118-A325 HydrophobicContact CB-CB 4.27Å; R118-D337 IonicContact CZ-OD1 3.29Å; R118-D337 IonicContact CZ-OD2 3.04Å; R118-D337 IonicContact NH1-OD1 3.57Å; R118-D337 PolarHBondContact NH1-OD1 2.83Å; R118-D337 IonicContact NH1-OD2 3.96Å; R118-D337 VanDerWaalsContact NH2-CG 3.3Å; R118-D337 IonicContact NH2-OD1 2.75Å; R118-D337 PolarHBondContact NH2-OD1 3.24Å; R118-D337 IonicContact NH2-OD2 3.18Å; R118-D337 PolarHBondContact NH2-OD2 3.34Å
119A97.7Very high97.3Very high5 Ų524.6 Ų24.64%0.04111%0.113CC..EExtended strand (participates in β ladder)trans-74.4151.2-177.500000113.2T112 M121T112-A119 HydrophobicContact CG2-CB 3.79Å; A119-M121 HydrophobicContact CB-CE 3.96Å; A119-M121 HydrophobicContact CB-CG 4.46Å
120F97.7Very high97.2Very high7 Ų726 Ų263%0.03112%0.12CC..EExtended strand (participates in β ladder)trans-83.7114.7173.1-173.7-114.4000111E82 V85 V86 S87 P122 I126 A129 L133 Y144E82-F120 HydrophobicContact CB-CB 4.37Å; E82-F120 HydrophobicContact CG-CB 4.25Å; E82-F120 WeakPolarHBondContact O-CB 3.39Å; V85-F120 WeakPolarHBondContact O-CB 3.35Å; V86-F120 HydrophobicContact CG2-CD1 4.11Å; V86-F120 HydrophobicContact CG2-CE1 4.28Å; S87-F120 WeakPolarHBondContact CB-O 3.22Å; S87-F120 PolarHBondContact N-O 2.96Å; F120-P122 HydrophobicContact CD1-CG 4.01Å; F120-P122 HydrophobicContact CE1-CB 3.81Å; F120-P122 HydrophobicContact CE1-CG 3.63Å; F120-P122 HydrophobicContact CZ-CB 3.95Å; F120-P122 HydrophobicContact CZ-CG 4.28Å; F120-P122 WeakPolarHBondContact O-CD 3.18Å; F120-I126 HydrophobicContact CZ-CD1 3.8Å; F120-A129 HydrophobicContact CD2-CB 4Å; F120-A129 HydrophobicContact CE2-CB 3.46Å; F120-A129 VanDerWaalsContact CE2-CB 3.46Å; F120-A129 HydrophobicContact CZ-CB 4.11Å; F120-L133 HydrophobicContact CD2-CD1 3.8Å; F120-L133 HydrophobicContact CE2-CD1 3.72Å; F120-Y144 HydrophobicContact CD1-CD2 4.27Å; F120-Y144 AromaticContact CE1-CD2 3.81Å; F120-Y144 HydrophobicContact CE1-CD2 3.81Å; F120-Y144 AromaticContact CE1-CG 3.94Å; F120-Y144 HydrophobicContact CE1-CG 3.94Å
121M97.2Very high97.1Very high13 Ų1329.3 Ų29.36%0.06414%0.135CC..  trans-125.779.3-174.7-62.2-165.6-177.900112.3A119 I273 N277 F324A119-M121 HydrophobicContact CB-CE 3.96Å; A119-M121 HydrophobicContact CB-CG 4.46Å; M121-I273 VanDerWaalsContact CE-O 3.31Å; M121-I273 WeakPolarHBondContact CE-O 3.39Å; M121-N277 HydrophobicContact SD-CB 3.56Å; M121-N277 VanDerWaalsContact SD-CB 3.56Å; M121-F324 HydrophobicContact CE-CD1 4.16Å; M121-F324 HydrophobicContact CE-CE1 3.86Å; M121-F324 HydrophobicContact SD-CD1 4.25Å; M121-F324 HydrophobicContact SD-CE1 4.23Å
122P97.2Very high96.9Very high0 Ų028.9 Ų28.90%013%0.133CC..  trans-82.3-15.7-170.532.2-38000115.4V86 F120 G124 G125 I126 F148 T154V86-P122 HydrophobicContact CG1-CG 4.04Å; V86-P122 HydrophobicContact CG2-CG 4.11Å; F120-P122 HydrophobicContact CD1-CG 4.01Å; F120-P122 HydrophobicContact CE1-CB 3.81Å; F120-P122 HydrophobicContact CE1-CG 3.63Å; F120-P122 HydrophobicContact CZ-CB 3.95Å; F120-P122 HydrophobicContact CZ-CG 4.28Å; F120-P122 WeakPolarHBondContact O-CD 3.18Å; P122-G124 VanDerWaalsContact C-N 3.26Å; P122-G124 PolarHBondContact O-N 3.47Å; P122-G125 CarbonylContact O-C 3.19Å; P122-G125 VanDerWaalsContact O-C 3.29Å; P122-G125 WeakPolarHBondContact O-CA 3.35Å; P122-G125 PolarHBondContact O-N 2.97Å; P122-I126 HydrophobicContact CB-CD1 4.01Å; P122-I126 PolarHBondContact O-N 2.79Å; P122-F148 HydrophobicContact CB-CD1 4.16Å; P122-F148 HydrophobicContact CB-CD2 3.62Å; P122-F148 HydrophobicContact CB-CE1 4.27Å; P122-F148 HydrophobicContact CB-CE2 3.78Å; P122-F148 HydrophobicContact CB-CG 3.85Å; P122-F148 HydrophobicContact CB-CZ 4.1Å; P122-F148 HydrophobicContact CG-CD1 4.26Å; P122-F148 HydrophobicContact CG-CD2 3.62Å; P122-F148 HydrophobicContact CG-CE1 3.88Å; P122-F148 HydrophobicContact CG-CE2 3.19Å; P122-F148 HydrophobicContact CG-CG 4.16Å; P122-F148 HydrophobicContact CG-CZ 3.34Å; P122-T154 VanDerWaalsContact O-CG2 3.23Å; P122-T154 WeakPolarHBondContact O-CG2 3.31Å
123Y97.3Very high96.8Very high84 Ų8428.9 Ų28.933%0.32913%0.133SC..THydrogen-bonded Turntrans-60.2-34.6-177.7-69.7-83000113.2V86 G125 F148 H152 T154 H155 Y512V86-Y123 HydrophobicContact CG1-CD2 4.4Å; V86-Y123 HydrophobicContact CG1-CE2 3.66Å; Y123-G125 PolarHBondContact O-N 2.78Å; Y123-F148 AromaticContact CD1-CE1 3.76Å; Y123-F148 HydrophobicContact CD1-CE1 3.76Å; Y123-F148 HydrophobicContact CD2-CE1 4.36Å; Y123-F148 AromaticContact CE1-CE1 3.7Å; Y123-F148 HydrophobicContact CE1-CE1 3.7Å; Y123-F148 HydrophobicContact CE1-CZ 4.2Å; Y123-F148 HydrophobicContact CE2-CE1 4.32Å; Y123-F148 HydrophobicContact CE2-CZ 4.19Å; Y123-F148 HydrophobicContact CG-CE1 4.09Å; Y123-F148 AromaticContact CZ-CE1 3.99Å; Y123-H152 AromaticContact CD1-CE1 3.74Å; Y123-H152 AromaticContact CE1-CE1 3.98Å; Y123-H152 AromaticContact CE1-NE2 3.82Å; Y123-T154 WeakPolarHBondContact O-CB 3.46Å; Y123-H155 PolarHBondContact O-N 3.07Å; Y123-Y512 HydrophobicContact CG-CD2 4.32Å; Y123-Y512 HydrophobicContact CG-CE2 4.42Å
124G96.3Very high96.8Very high3 Ų331.4 Ų31.43%0.03114%0.143CC..THydrogen-bonded Turntrans-65.8-26.717200000113.4P122 N156P122-G124 VanDerWaalsContact C-N 3.26Å; P122-G124 PolarHBondContact O-N 3.47Å; G124-N156 VanDerWaalsContact O-CB 3.28Å; G124-N156 WeakPolarHBondContact O-CB 3.08Å; G124-N156 PolarHBondContact O-N 3.27Å
125G97Very high96.5Very high4 Ų434 Ų344%0.04115%0.15CC..  trans155.6118.1176.800000113.5P122 Y123 R127 M128 A129P122-G125 CarbonylContact O-C 3.19Å; P122-G125 VanDerWaalsContact O-C 3.29Å; P122-G125 WeakPolarHBondContact O-CA 3.35Å; P122-G125 PolarHBondContact O-N 2.97Å; Y123-G125 PolarHBondContact O-N 2.78Å; G125-R127 PolarHBondContact O-N 2.86Å; G125-M128 VanDerWaalsContact CA-CE 3.48Å; G125-M128 PolarHBondContact O-N 3.14Å; G125-A129 PolarHBondContact O-N 2.95Å
126I97.3Very high96.2Very high4 Ų436.1 Ų36.12%0.02116%0.156CC..Hα-helixtrans-60.4-44.3-175.9-175.458.3000112.4F120 P122 M128 A129 E130 F148 N149 T154F120-I126 HydrophobicContact CZ-CD1 3.8Å; P122-I126 HydrophobicContact CB-CD1 4.01Å; P122-I126 PolarHBondContact O-N 2.79Å; I126-M128 VanDerWaalsContact C-N 3.26Å; I126-M128 PolarHBondContact O-N 3.42Å; I126-A129 WeakPolarHBondContact O-CB 3.36Å; I126-A129 PolarHBondContact O-N 3.44Å; I126-E130 HydrophobicContact CD1-CG 3.94Å; I126-E130 HydrophobicContact CG1-CG 4.11Å; I126-E130 WeakPolarHBondContact O-CG 3.44Å; I126-E130 PolarHBondContact O-N 2.86Å; I126-F148 HydrophobicContact CB-CB 3.65Å; I126-F148 HydrophobicContact CD1-CB 4.14Å; I126-F148 HydrophobicContact CD1-CD2 4.41Å; I126-F148 HydrophobicContact CG1-CB 3.94Å; I126-F148 HydrophobicContact CG2-CB 4.17Å; I126-N149 WeakPolarHBondContact CG2-OD1 3.39Å; I126-T154 HydrophobicContact CB-CG2 4.44Å; I126-T154 HydrophobicContact CG2-CG2 4.5Å
127R95.8Very high96Very high136 Ų13639 Ų3951%0.51319%0.188SC..Hα-helixtrans-55.6-41.1-179.6-172.8-177.967-168.4-5.1112.7G125 E131G125-R127 PolarHBondContact O-N 2.86Å; R127-E131 VanDerWaalsContact O-CB 3.28Å; R127-E131 WeakPolarHBondContact O-CB 3.41Å; R127-E131 PolarHBondContact O-N 2.82Å
128M95.9Very high95.9Very high11 Ų1141.3 Ų41.35%0.05420%0.196CC..Hα-helixtrans-73.9-36.8-180-71.266.660.100111.5G125 I126 E130 E131 S132 N156 T182 I327G125-M128 VanDerWaalsContact CA-CE 3.48Å; G125-M128 PolarHBondContact O-N 3.14Å; I126-M128 VanDerWaalsContact C-N 3.26Å; I126-M128 PolarHBondContact O-N 3.42Å; M128-E130 VanDerWaalsContact C-N 3.33Å; M128-E131 PolarHBondContact O-N 3.18Å; M128-S132 WeakPolarHBondContact O-CB 3.43Å; M128-S132 PolarHBondContact O-N 3.04Å; M128-S132 PolarHBondContact O-OG 3.32Å; M128-N156 HydrophobicContact CE-CB 3.26Å; M128-N156 WeakPolarHBondContact CE-OD1 3.36Å; M128-T182 HydrophobicContact CG-CG2 4.37Å; M128-T182 HydrophobicContact SD-CG2 4.09Å; M128-I327 HydrophobicContact CB-CG2 3.79Å; M128-I327 HydrophobicContact CG-CD1 3.76Å; M128-I327 HydrophobicContact CG-CG2 4.08Å; M128-I327 VanDerWaalsContact O-CG2 3.31Å; M128-I327 WeakPolarHBondContact O-CG2 3.48Å
129A96.4Very high95.8Very high12 Ų1246.7 Ų46.710%0.09923%0.23CC..Hα-helixtrans-63.3-41175.400000111.4F120 G125 I126 L133F120-A129 HydrophobicContact CD2-CB 4Å; F120-A129 HydrophobicContact CE2-CB 3.46Å; F120-A129 VanDerWaalsContact CE2-CB 3.46Å; F120-A129 HydrophobicContact CZ-CB 4.11Å; G125-A129 PolarHBondContact O-N 2.95Å; I126-A129 WeakPolarHBondContact O-CB 3.36Å; I126-A129 PolarHBondContact O-N 3.44Å; A129-L133 WeakPolarHBondContact O-CG 3.22Å; A129-L133 PolarHBondContact O-N 3.43Å
130E96.4Very high95.7Very high30 Ų3047.3 Ų47.314%0.1423%0.234CC..Hα-helixtrans-67.7-47.4175.5-63.5178.9151.900112I126 M128 S132 L133 E134 P140 T145I126-E130 HydrophobicContact CD1-CG 3.94Å; I126-E130 HydrophobicContact CG1-CG 4.11Å; I126-E130 WeakPolarHBondContact O-CG 3.44Å; I126-E130 PolarHBondContact O-N 2.86Å; M128-E130 VanDerWaalsContact C-N 3.33Å; E130-S132 VanDerWaalsContact C-N 3.27Å; E130-S132 PolarHBondContact O-N 2.89Å; E130-L133 WeakPolarHBondContact O-CB 3.28Å; E130-L133 PolarHBondContact O-N 2.86Å; E130-E134 WeakPolarHBondContact O-CG 3.49Å; E130-E134 PolarHBondContact O-N 3.39Å; E130-P140 HydrophobicContact CB-CB 4.24Å; E130-P140 HydrophobicContact CB-CG 3.88Å; E130-P140 HydrophobicContact CG-CB 3.91Å; E130-P140 HydrophobicContact CG-CG 4.12Å; E130-T145 WeakPolarHBondContact OE1-CB 3.11Å; E130-T145 VanDerWaalsContact OE1-CG2 3.27Å; E130-T145 WeakPolarHBondContact OE1-CG2 3.45Å; E130-T145 PolarHBondContact OE1-OG1 2.93Å
131E96Very high95.7Very high75 Ų7548.8 Ų48.835%0.3524%0.242SC..Hα-helixtrans-58.3-40.7177.4-176.8-177.215800111.6R127 M128 R135 I327R127-E131 VanDerWaalsContact O-CB 3.28Å; R127-E131 WeakPolarHBondContact O-CB 3.41Å; R127-E131 PolarHBondContact O-N 2.82Å; M128-E131 PolarHBondContact O-N 3.18Å; E131-R135 VanDerWaalsContact O-CB 3.28Å; E131-R135 WeakPolarHBondContact O-CB 3.23Å; E131-R135 PolarHBondContact O-N 2.68Å; E131-I327 HydrophobicContact CB-CG2 4.07Å; E131-I327 HydrophobicContact CG-CG2 4.16Å
132S94.5Very high95.7Very high2 Ų252.8 Ų52.81%0.01427%0.269CS..Hα-helixtrans-61.4-42.4173.5-74.70000112.4M128 E130 Y136 R326 I327M128-S132 WeakPolarHBondContact O-CB 3.43Å; M128-S132 PolarHBondContact O-N 3.04Å; M128-S132 PolarHBondContact O-OG 3.32Å; E130-S132 VanDerWaalsContact C-N 3.27Å; E130-S132 PolarHBondContact O-N 2.89Å; S132-Y136 VanDerWaalsContact O-CD2 3.29Å; S132-Y136 WeakPolarHBondContact O-CD2 3.3Å; S132-R326 PolarHBondContact OG-O 2.7Å; S132-I327 WeakPolarHBondContact OG-CG2 3.43Å; S132-I327 PolarHBondContact OG-N 2.75Å
133L96.2Very high95.7Very high1 Ų158.4 Ų58.41%0.00529%0.293CS..Hα-helixtrans-64.8-51.4177.8-73170.6000111.8M81 E82 A83 F120 A129 E130 R135 Y136 G137 Y138M81-L133 HydrophobicContact CB-CD2 3.9Å; M81-L133 HydrophobicContact CE-CD2 3.77Å; M81-L133 HydrophobicContact CE-CG 4.3Å; M81-L133 HydrophobicContact SD-CD2 4.21Å; E82-L133 WeakPolarHBondContact O-CD2 3.35Å; A83-L133 HydrophobicContact CB-CD1 3.95Å; A83-L133 HydrophobicContact CB-CD2 4.05Å; F120-L133 HydrophobicContact CD2-CD1 3.8Å; F120-L133 HydrophobicContact CE2-CD1 3.72Å; A129-L133 WeakPolarHBondContact O-CG 3.22Å; A129-L133 PolarHBondContact O-N 3.43Å; E130-L133 WeakPolarHBondContact O-CB 3.28Å; E130-L133 PolarHBondContact O-N 2.86Å; L133-R135 PolarHBondContact O-N 3.03Å; L133-Y136 CarbonylContact O-C 3.54Å; L133-Y136 PolarHBondContact O-N 3.01Å; L133-Y136 VanDerWaalsContact O-N 3.11Å; L133-G137 PolarHBondContact O-N 3.3Å; L133-Y138 CarbonylContact C-O 3.12Å; L133-Y138 HydrophobicContact CD2-CG 4.23Å; L133-Y138 WeakPolarHBondContact O-CB 3.29Å; L133-Y138 PolarHBondContact O-N 3.23Å
134E95.7Very high95.7Very high124 Ų12455.9 Ų55.958%0.57928%0.283SS*.Hα-helixtrans-59.7-37.7-178.1-69.1177.716200111.5E130 Y136 G137 Y138 P140E130-E134 WeakPolarHBondContact O-CG 3.49Å; E130-E134 PolarHBondContact O-N 3.39Å; E134-Y136 PolarHBondContact O-N 3.18Å; E134-G137 PolarHBondContact O-N 3.49Å; E134-Y138 WeakPolarHBondContact CA-O 3.45Å; E134-P140 HydrophobicContact CG-CG 3.73Å
135R91.2Very high95.6Very high156 Ų15657.6 Ų57.659%0.58929%0.293SS*.Hα-helixtrans-57-34.8178.2176.961.4-173105.3-5.4113.2E131 L133 P328E131-R135 VanDerWaalsContact O-CB 3.28Å; E131-R135 WeakPolarHBondContact O-CB 3.23Å; E131-R135 PolarHBondContact O-N 2.68Å; L133-R135 PolarHBondContact O-N 3.03Å; R135-P328 HydrophobicContact CG-CG 4.4Å
136Y91.7Very high95.7Very high61 Ų6161.5 Ų61.524%0.23931%0.31CS..THydrogen-bonded Turntrans-10315.6-179.4-66-75.6000112.8V78 M81 S132 L133 E134 Y138V78-Y136 HydrophobicContact CB-CD1 3.81Å; V78-Y136 HydrophobicContact CB-CD2 4.46Å; V78-Y136 HydrophobicContact CB-CE1 3.78Å; V78-Y136 HydrophobicContact CB-CE2 4.46Å; V78-Y136 HydrophobicContact CB-CG 4.17Å; V78-Y136 HydrophobicContact CG1-CG 4.43Å; V78-Y136 HydrophobicContact CG2-CD1 3.81Å; V78-Y136 HydrophobicContact CG2-CD2 3.98Å; V78-Y136 HydrophobicContact CG2-CE1 3.33Å; V78-Y136 HydrophobicContact CG2-CE2 3.55Å; V78-Y136 HydrophobicContact CG2-CG 4.12Å; M81-Y136 HydrophobicContact SD-CD2 3.7Å; M81-Y136 HydrophobicContact SD-CG 4.09Å; S132-Y136 VanDerWaalsContact O-CD2 3.29Å; S132-Y136 WeakPolarHBondContact O-CD2 3.3Å; L133-Y136 CarbonylContact O-C 3.54Å; L133-Y136 PolarHBondContact O-N 3.01Å; L133-Y136 VanDerWaalsContact O-N 3.11Å; E134-Y136 PolarHBondContact O-N 3.18Å; Y136-Y138 WeakPolarHBondContact O-CD2 3.44Å; Y136-Y138 WeakPolarHBondContact O-CE2 3.3Å
137G93.6Very high95.7Very high68 Ų6863.7 Ų63.770%0.70132%0.321SS*.THydrogen-bonded Turntrans81.610.8173.400000115.3L133 E134L133-G137 PolarHBondContact O-N 3.3Å; E134-G137 PolarHBondContact O-N 3.49Å
138Y95.7Very high95.8Very high66 Ų6657.5 Ų57.526%0.25930%0.298SS..PPolyproline II helixtrans-86147174.1-65.9-100.2000110.2D80 M81 L133 E134 Y136D80-Y138 WeakPolarHBondContact CA-OH 3.41Å; D80-Y138 PolarHBondContact OD1-OH 3.33Å; M81-Y138 HydrophobicContact CB-CD1 4.16Å; M81-Y138 HydrophobicContact CB-CD2 3.95Å; M81-Y138 HydrophobicContact CB-CE1 4.05Å; M81-Y138 HydrophobicContact CB-CE2 3.86Å; M81-Y138 HydrophobicContact CB-CG 4.13Å; M81-Y138 HydrophobicContact CG-CD2 4.14Å; M81-Y138 HydrophobicContact CG-CE2 3.92Å; M81-Y138 PolarHBondContact N-OH 2.73Å; M81-Y138 HydrophobicContact SD-CD2 4.06Å; M81-Y138 HydrophobicContact SD-CE2 4.3Å; L133-Y138 CarbonylContact C-O 3.12Å; L133-Y138 HydrophobicContact CD2-CG 4.23Å; L133-Y138 WeakPolarHBondContact O-CB 3.29Å; L133-Y138 PolarHBondContact O-N 3.23Å; E134-Y138 WeakPolarHBondContact CA-O 3.45Å; Y136-Y138 WeakPolarHBondContact O-CD2 3.44Å; Y136-Y138 WeakPolarHBondContact O-CE2 3.3Å
139T96Very high95.7Very high119 Ų11960.9 Ų60.973%0.7332%0.317SS*.PPolyproline II helixtrans-94.7122.3176.7-57.90000109.5
140P95.8Very high95.7Very high18 Ų1866 Ų6612%0.11734%0.342CS..PPolyproline II helixtrans-55.7137.7172.6-29.137.4000112.8E130 E134 P142E130-P140 HydrophobicContact CB-CB 4.24Å; E130-P140 HydrophobicContact CB-CG 3.88Å; E130-P140 HydrophobicContact CG-CB 3.91Å; E130-P140 HydrophobicContact CG-CG 4.12Å; E134-P140 HydrophobicContact CG-CG 3.73Å; P140-P142 VanDerWaalsContact O-CD 3.27Å; P140-P142 WeakPolarHBondContact O-CD 3.3Å
141N96.6Very high95.7Very high38 Ų3872.3 Ų72.320%0.20337%0.366CS..  trans-76.1115.4175.4-172.9-36.3000110.1A83 D84 K143 Y144 T145A83-N141 WeakPolarHBondContact O-CB 3.39Å; D84-N141 PolarHBondContact OD1-ND2 2.88Å; N141-K143 PolarHBondContact O-N 2.84Å; N141-K143 VanDerWaalsContact OD1-CB 3.23Å; N141-K143 WeakPolarHBondContact OD1-CB 3.48Å; N141-K143 PolarHBondContact OD1-N 2.77Å; N141-Y144 HydrophobicContact CB-CD2 3.84Å; N141-Y144 HydrophobicContact CB-CE2 4.31Å; N141-Y144 PolarHBondContact O-N 2.71Å; N141-T145 PolarHBondContact O-N 2.96Å; N141-T145 PolarHBondContact O-OG1 3.01Å
142P96.7Very high95.8Very high97 Ų9772 Ų7263%0.6337%0.365SS*.Hα-helixtrans-59.6-25.2-174.4-24.334.5000114P140 Y144 T145 E146P140-P142 VanDerWaalsContact O-CD 3.27Å; P140-P142 WeakPolarHBondContact O-CD 3.3Å; P142-Y144 VanDerWaalsContact C-N 3.32Å; P142-Y144 PolarHBondContact O-N 2.7Å; P142-T145 WeakPolarHBondContact O-CB 3.38Å; P142-T145 PolarHBondContact O-N 3.32Å; P142-E146 PolarHBondContact O-N 3.08Å
143K97.7Very high95.9Very high118 Ų11875.5 Ų75.551%0.51338%0.379SS..Hα-helixtrans-62-40.9175.7-178.9-169.9170.5-167.20111.3N141 E146 I147N141-K143 PolarHBondContact O-N 2.84Å; N141-K143 VanDerWaalsContact OD1-CB 3.23Å; N141-K143 WeakPolarHBondContact OD1-CB 3.48Å; N141-K143 PolarHBondContact OD1-N 2.77Å; K143-E146 PolarHBondContact O-N 3.46Å; K143-I147 HydrophobicContact CG-CD1 4.01Å; K143-I147 VanDerWaalsContact O-CG1 3.28Å; K143-I147 WeakPolarHBondContact O-CG1 3.2Å; K143-I147 PolarHBondContact O-N 3.44Å
144Y97.2Very high96Very high31 Ų3175.6 Ų75.612%0.12238%0.38CS..Hα-helixtrans-78.5-30.6179.4-62.2-49000111.9D84 V86 F120 N141 P142 E146 I147 F148D84-Y144 WeakPolarHBondContact O-CE2 3.17Å; D84-Y144 PolarHBondContact O-OH 3.4Å; V86-Y144 HydrophobicContact CG2-CD1 3.61Å; V86-Y144 HydrophobicContact CG2-CD2 4.34Å; V86-Y144 HydrophobicContact CG2-CE1 3.47Å; V86-Y144 VanDerWaalsContact CG2-CE1 3.47Å; V86-Y144 HydrophobicContact CG2-CE2 4.22Å; V86-Y144 HydrophobicContact CG2-CG 4.09Å; F120-Y144 HydrophobicContact CD1-CD2 4.27Å; F120-Y144 AromaticContact CE1-CD2 3.81Å; F120-Y144 HydrophobicContact CE1-CD2 3.81Å; F120-Y144 AromaticContact CE1-CG 3.94Å; F120-Y144 HydrophobicContact CE1-CG 3.94Å; N141-Y144 HydrophobicContact CB-CD2 3.84Å; N141-Y144 HydrophobicContact CB-CE2 4.31Å; N141-Y144 PolarHBondContact O-N 2.71Å; P142-Y144 VanDerWaalsContact C-N 3.32Å; P142-Y144 PolarHBondContact O-N 2.7Å; Y144-E146 VanDerWaalsContact C-N 3.31Å; Y144-E146 PolarHBondContact O-N 3.33Å; Y144-I147 HydrophobicContact CD1-CD1 4.01Å; Y144-I147 HydrophobicContact CE1-CD1 4.35Å; Y144-I147 PolarHBondContact O-N 2.78Å; Y144-F148 HydrophobicContact CD1-CE2 4.29Å; Y144-F148 WeakPolarHBondContact O-CD2 3.41Å; Y144-F148 PolarHBondContact O-N 2.77Å
145T95.3Very high96.2Very high39 Ų3969.7 Ų69.724%0.23935%0.352CS..Hα-helixtrans-54.5-49.5166.6-460000110.7E130 N141 P142 N149E130-T145 WeakPolarHBondContact OE1-CB 3.11Å; E130-T145 VanDerWaalsContact OE1-CG2 3.27Å; E130-T145 WeakPolarHBondContact OE1-CG2 3.45Å; E130-T145 PolarHBondContact OE1-OG1 2.93Å; N141-T145 PolarHBondContact O-N 2.96Å; N141-T145 PolarHBondContact O-OG1 3.01Å; P142-T145 WeakPolarHBondContact O-CB 3.38Å; P142-T145 PolarHBondContact O-N 3.32Å; T145-N149 WeakPolarHBondContact CG2-ND2 3.3Å; T145-N149 WeakPolarHBondContact O-CB 3.16Å; T145-N149 PolarHBondContact O-N 3.1Å; T145-N149 VanDerWaalsContact O-N 3.09Å; T145-N149 PolarHBondContact O-ND2 3.46Å
146E97.6Very high96.5Very high86 Ų8662.5 Ų62.540%0.40233%0.326SS..Hα-helixtrans-61.8-49.7177-171.4-171.1170.100111.1P142 K143 Y144 F148 N149 D150 Y151P142-E146 PolarHBondContact O-N 3.08Å; K143-E146 PolarHBondContact O-N 3.46Å; Y144-E146 VanDerWaalsContact C-N 3.31Å; Y144-E146 PolarHBondContact O-N 3.33Å; E146-F148 PolarHBondContact O-N 3.48Å; E146-N149 PolarHBondContact O-N 2.64Å; E146-D150 VanDerWaalsContact O-CB 3.3Å; E146-D150 WeakPolarHBondContact O-CB 3.25Å; E146-D150 PolarHBondContact O-N 2.95Å; E146-Y151 HydrophobicContact CG-CE2 3.77Å; E146-Y151 WeakPolarHBondContact OE1-CE2 3.48Å; E146-Y151 PolarHBondContact OE1-OH 3.5Å
147I98.2Very high96.8Very high49 Ų4963.5 Ų63.525%0.25133%0.333SS..Iπ-helixtrans-59-49.3-177.7-70.1164.7000112.2K143 Y144 Y151 H152K143-I147 HydrophobicContact CG-CD1 4.01Å; K143-I147 VanDerWaalsContact O-CG1 3.28Å; K143-I147 WeakPolarHBondContact O-CG1 3.2Å; K143-I147 PolarHBondContact O-N 3.44Å; Y144-I147 HydrophobicContact CD1-CD1 4.01Å; Y144-I147 HydrophobicContact CE1-CD1 4.35Å; Y144-I147 PolarHBondContact O-N 2.78Å; I147-Y151 HydrophobicContact CB-CD2 4.49Å; I147-Y151 HydrophobicContact CG1-CD2 4.13Å; I147-Y151 CarbonylContact O-C 3.6Å; I147-Y151 WeakPolarHBondContact O-CA 3.48Å; I147-Y151 PolarHBondContact O-N 2.94Å; I147-Y151 VanDerWaalsContact O-N 3.08Å; I147-H152 PolarHBondContact O-N 2.74Å
148F97.7Very high97Very high7 Ų760.3 Ų60.33%0.03130%0.299CS..Iπ-helixtrans-90.3-1.7-172.3-68.4-78.6000114.5V86 P122 Y123 I126 Y144 E146 H152 T154V86-F148 HydrophobicContact CG1-CZ 4.29Å; V86-F148 HydrophobicContact CG2-CE2 3.94Å; V86-F148 HydrophobicContact CG2-CZ 4.33Å; P122-F148 HydrophobicContact CB-CD1 4.16Å; P122-F148 HydrophobicContact CB-CD2 3.62Å; P122-F148 HydrophobicContact CB-CE1 4.27Å; P122-F148 HydrophobicContact CB-CE2 3.78Å; P122-F148 HydrophobicContact CB-CG 3.85Å; P122-F148 HydrophobicContact CB-CZ 4.1Å; P122-F148 HydrophobicContact CG-CD1 4.26Å; P122-F148 HydrophobicContact CG-CD2 3.62Å; P122-F148 HydrophobicContact CG-CE1 3.88Å; P122-F148 HydrophobicContact CG-CE2 3.19Å; P122-F148 HydrophobicContact CG-CG 4.16Å; P122-F148 HydrophobicContact CG-CZ 3.34Å; Y123-F148 AromaticContact CD1-CE1 3.76Å; Y123-F148 HydrophobicContact CD1-CE1 3.76Å; Y123-F148 HydrophobicContact CD2-CE1 4.36Å; Y123-F148 AromaticContact CE1-CE1 3.7Å; Y123-F148 HydrophobicContact CE1-CE1 3.7Å; Y123-F148 HydrophobicContact CE1-CZ 4.2Å; Y123-F148 HydrophobicContact CE2-CE1 4.32Å; Y123-F148 HydrophobicContact CE2-CZ 4.19Å; Y123-F148 HydrophobicContact CG-CE1 4.09Å; Y123-F148 AromaticContact CZ-CE1 3.99Å; I126-F148 HydrophobicContact CB-CB 3.65Å; I126-F148 HydrophobicContact CD1-CB 4.14Å; I126-F148 HydrophobicContact CD1-CD2 4.41Å; I126-F148 HydrophobicContact CG1-CB 3.94Å; I126-F148 HydrophobicContact CG2-CB 4.17Å; Y144-F148 HydrophobicContact CD1-CE2 4.29Å; Y144-F148 WeakPolarHBondContact O-CD2 3.41Å; Y144-F148 PolarHBondContact O-N 2.77Å; E146-F148 PolarHBondContact O-N 3.48Å; F148-H152 CarbonylContact C-O 3.34Å; F148-H152 WeakPolarHBondContact CA-O 3.47Å; F148-H152 HydrophobicContact CD1-CB 4.18Å; F148-H152 HydrophobicContact CE1-CB 4.43Å; F148-H152 VanDerWaalsContact O-O 3.07Å; F148-T154 HydrophobicContact CB-CG2 3.93Å; F148-T154 HydrophobicContact CD1-CG2 4Å; F148-T154 HydrophobicContact CG-CG2 4.39Å
149N93.6Very high97.2Very high82 Ų8257.1 Ų57.144%0.43929%0.287SS..Iπ-helixtrans-99.4-44.5165.7-73.3-51.8000112I126 T145 E146I126-N149 WeakPolarHBondContact CG2-OD1 3.39Å; T145-N149 WeakPolarHBondContact CG2-ND2 3.3Å; T145-N149 WeakPolarHBondContact O-CB 3.16Å; T145-N149 PolarHBondContact O-N 3.1Å; T145-N149 VanDerWaalsContact O-N 3.09Å; T145-N149 PolarHBondContact O-ND2 3.46Å; E146-N149 PolarHBondContact O-N 2.64Å
150D95.8Very high97.3Very high119 Ų11952.8 Ų52.864%0.63626%0.258SS*.Iπ-helixtrans-101.7-32.6-166.5-59.1-23.2000113.4E146E146-D150 VanDerWaalsContact O-CB 3.3Å; E146-D150 WeakPolarHBondContact O-CB 3.25Å; E146-D150 PolarHBondContact O-N 2.95Å
151Y97.4Very high97.4Very high163 Ų16356.2 Ų56.264%0.63928%0.275SS*.Iπ-helixtrans-108.8-36.3-173-54-46.2000114E146 I147E146-Y151 HydrophobicContact CG-CE2 3.77Å; E146-Y151 WeakPolarHBondContact OE1-CE2 3.48Å; E146-Y151 PolarHBondContact OE1-OH 3.5Å; I147-Y151 HydrophobicContact CB-CD2 4.49Å; I147-Y151 HydrophobicContact CG1-CD2 4.13Å; I147-Y151 CarbonylContact O-C 3.6Å; I147-Y151 WeakPolarHBondContact O-CA 3.48Å; I147-Y151 PolarHBondContact O-N 2.94Å; I147-Y151 VanDerWaalsContact O-N 3.08Å
152H97.4Very high97.5Very high69 Ų6957.8 Ų57.832%0.31929%0.286SS..SBendtrans-127.8106-178-169-63.6000110.6Y123 I147 F148 T154Y123-H152 AromaticContact CD1-CE1 3.74Å; Y123-H152 AromaticContact CE1-CE1 3.98Å; Y123-H152 AromaticContact CE1-NE2 3.82Å; I147-H152 PolarHBondContact O-N 2.74Å; F148-H152 CarbonylContact C-O 3.34Å; F148-H152 WeakPolarHBondContact CA-O 3.47Å; F148-H152 HydrophobicContact CD1-CB 4.18Å; F148-H152 HydrophobicContact CE1-CB 4.43Å; F148-H152 VanDerWaalsContact O-O 3.07Å; H152-T154 PolarHBondContact O-N 3.34Å
153K97.9Very high97.6Very high74 Ų7453.8 Ų53.832%0.32226%0.258SS..  trans-63.3135.4174.9-163.8176.5-164.21800110.6Q157 A158 D161 Y511K153-Q157 HydrophobicContact CG-CB 4.3Å; K153-Q157 HydrophobicContact CG-CG 4.41Å; K153-A158 HydrophobicContact CD-CB 4.04Å; K153-A158 HydrophobicContact CG-CB 4.33Å; K153-D161 WeakPolarHBondContact CE-OD2 3.47Å; K153-D161 IonicContact NZ-OD2 3.43Å; K153-D161 PolarHBondContact NZ-OD2 3.48Å; K153-Y511 HydrophobicContact CB-CD1 4.16Å; K153-Y511 HydrophobicContact CB-CE1 3.8Å; K153-Y511 HydrophobicContact CD-CE1 4.21Å; K153-Y511 HydrophobicContact CG-CE1 4.32Å; K153-Y511 VanDerWaalsContact O-CD1 3.29Å; K153-Y511 WeakPolarHBondContact O-CD1 3.32Å
154T98.4Very high97.6Very high3 Ų350.9 Ų50.92%0.01825%0.251CS..  trans-92.4160.317959.40000111.7P122 Y123 I126 F148 H152 N156 Q157 A158P122-T154 VanDerWaalsContact O-CG2 3.23Å; P122-T154 WeakPolarHBondContact O-CG2 3.31Å; Y123-T154 WeakPolarHBondContact O-CB 3.46Å; I126-T154 HydrophobicContact CB-CG2 4.44Å; I126-T154 HydrophobicContact CG2-CG2 4.5Å; F148-T154 HydrophobicContact CB-CG2 3.93Å; F148-T154 HydrophobicContact CD1-CG2 4Å; F148-T154 HydrophobicContact CG-CG2 4.39Å; H152-T154 PolarHBondContact O-N 3.34Å; T154-N156 VanDerWaalsContact C-N 3.33Å; T154-N156 PolarHBondContact O-N 2.88Å; T154-Q157 PolarHBondContact O-N 3.43Å; T154-Q157 PolarHBondContact OG1-N 3.35Å; T154-A158 WeakPolarHBondContact O-CB 3.21Å; T154-A158 PolarHBondContact O-N 3.05Å
155H98.5Very high97.6Very high0 Ų054 Ų540%028%0.275CS..Hα-helixtrans-50.4-52.5173.6167.256.4000111.4Y123 Q157 A158 V159 P180 I504 H508Y123-H155 PolarHBondContact O-N 3.07Å; H155-Q157 PolarHBondContact O-N 2.91Å; H155-A158 PolarHBondContact O-N 3.47Å; H155-V159 WeakPolarHBondContact CE1-CG2 3.45Å; H155-V159 WeakPolarHBondContact O-CG2 3.49Å; H155-V159 PolarHBondContact O-N 3.14Å; H155-P180 PolarHBondContact NE2-O 3.28Å; H155-I504 PolarHBondContact CE1-O 3.22Å; H155-H508 AromaticContact CD2-CD2 3.79Å; H155-H508 AromaticContact CE1-CD2 3.8Å; H155-H508 WeakPolarHBondContact ND1-CA 3.4Å; H155-H508 PolarHBondContact ND1-N 3.3Å; H155-H508 AromaticContact NE2-CD2 3.62Å
156N98.2Very high97.7Very high5 Ų557.2 Ų57.23%0.02729%0.287CS..Hα-helixtrans-54.8-53.3178.5174.9-106.1000113.2G124 M128 T154 A158 V159 F160 D181G124-N156 VanDerWaalsContact O-CB 3.28Å; G124-N156 WeakPolarHBondContact O-CB 3.08Å; G124-N156 PolarHBondContact O-N 3.27Å; M128-N156 HydrophobicContact CE-CB 3.26Å; M128-N156 WeakPolarHBondContact CE-OD1 3.36Å; T154-N156 VanDerWaalsContact C-N 3.33Å; T154-N156 PolarHBondContact O-N 2.88Å; N156-A158 PolarHBondContact O-N 3.48Å; N156-V159 PolarHBondContact O-N 2.77Å; N156-F160 WeakPolarHBondContact ND2-CD2 3.45Å; N156-F160 WeakPolarHBondContact ND2-CE2 3.45Å; N156-F160 WeakPolarHBondContact O-CD2 3.46Å; N156-F160 PolarHBondContact O-N 3.33Å; N156-D181 PolarHBondContact ND2-O 2.76Å
157Q98.1Very high97.7Very high83 Ų8353.7 Ų53.739%0.38827%0.271SS..Hα-helixtrans-60.8-39.6-178.4-173.860.45500110.7K153 T154 H155 F160 D161K153-Q157 HydrophobicContact CG-CB 4.3Å; K153-Q157 HydrophobicContact CG-CG 4.41Å; T154-Q157 PolarHBondContact O-N 3.43Å; T154-Q157 PolarHBondContact OG1-N 3.35Å; H155-Q157 PolarHBondContact O-N 2.91Å; Q157-F160 PolarHBondContact O-N 3.18Å; Q157-D161 PolarHBondContact NE2-OD1 3.16Å; Q157-D161 WeakPolarHBondContact O-CB 3.45Å; Q157-D161 PolarHBondContact O-N 2.97Å
158A98.3Very high97.7Very high0 Ų056.1 Ų56.10%028%0.277CS..Hα-helixtrans-66-40.4179.100000113.8K153 T154 H155 N156 D161 M507 Y511K153-A158 HydrophobicContact CD-CB 4.04Å; K153-A158 HydrophobicContact CG-CB 4.33Å; T154-A158 WeakPolarHBondContact O-CB 3.21Å; T154-A158 PolarHBondContact O-N 3.05Å; H155-A158 PolarHBondContact O-N 3.47Å; N156-A158 PolarHBondContact O-N 3.48Å; A158-D161 PolarHBondContact O-N 3.23Å; A158-M507 HydrophobicContact CB-CB 4.08Å; A158-M507 HydrophobicContact CB-CG 3.96Å; A158-M507 HydrophobicContact CB-SD 3.69Å; A158-Y511 HydrophobicContact CB-CD2 3.36Å; A158-Y511 HydrophobicContact CB-CE2 3.18Å; A158-Y511 HydrophobicContact CB-CG 4.32Å
159V98.6Very high97.7Very high0 Ų057.4 Ų57.40%029%0.289CS..Hα-helixtrans-61.5-50.2174.1171.10000110.8H155 N156 D161 V162 Y163 D181 I504 M507H155-V159 WeakPolarHBondContact CE1-CG2 3.45Å; H155-V159 WeakPolarHBondContact O-CG2 3.49Å; H155-V159 PolarHBondContact O-N 3.14Å; N156-V159 PolarHBondContact O-N 2.77Å; V159-D161 VanDerWaalsContact C-N 3.27Å; V159-D161 PolarHBondContact O-N 3.07Å; V159-V162 VanDerWaalsContact O-CG2 3.25Å; V159-V162 WeakPolarHBondContact O-CG2 3.32Å; V159-V162 PolarHBondContact O-N 3.46Å; V159-V162 VanDerWaalsContact O-N 3.15Å; V159-Y163 HydrophobicContact CG1-CD1 3.8Å; V159-Y163 HydrophobicContact CG1-CD2 4.39Å; V159-Y163 HydrophobicContact CG1-CE1 3.25Å; V159-Y163 HydrophobicContact CG1-CE2 3.88Å; V159-Y163 HydrophobicContact CG1-CG 4.36Å; V159-Y163 WeakPolarHBondContact O-CD1 3.49Å; V159-Y163 PolarHBondContact O-N 2.86Å; V159-Y163 VanDerWaalsContact O-N 3.11Å; V159-D181 HydrophobicContact CG1-CB 3.85Å; V159-I504 HydrophobicContact CG1-CG1 3.96Å; V159-I504 HydrophobicContact CG2-CG1 4.34Å; V159-M507 HydrophobicContact CG2-CB 3.65Å; V159-M507 HydrophobicContact CG2-CG 4.04Å
160F98Very high98Very high28 Ų2853.6 Ų53.612%0.12327%0.269CS..Hα-helixtrans-66.5-29.7-177.5-83.5-92.5000112.3N156 Q157 V162 Y163 R168 D181N156-F160 WeakPolarHBondContact ND2-CD2 3.45Å; N156-F160 WeakPolarHBondContact ND2-CE2 3.45Å; N156-F160 WeakPolarHBondContact O-CD2 3.46Å; N156-F160 PolarHBondContact O-N 3.33Å; Q157-F160 PolarHBondContact O-N 3.18Å; F160-V162 PolarHBondContact O-N 3.16Å; F160-Y163 HydrophobicContact CD1-CD2 4.28Å; F160-Y163 HydrophobicContact CE1-CD2 4.34Å; F160-Y163 PolarHBondContact O-N 3.2Å; F160-R168 PolarHBondContact O-NH2 3.4Å; F160-D181 HydrophobicContact CE2-CB 4.1Å
161D98.2Very high98Very high89 Ų8950.9 Ų50.948%0.47625%0.25SC..Hα-helixtrans-65.8-23.3175.9-75.4-3.7000114K153 Q157 A158 V159K153-D161 WeakPolarHBondContact CE-OD2 3.47Å; K153-D161 IonicContact NZ-OD2 3.43Å; K153-D161 PolarHBondContact NZ-OD2 3.48Å; Q157-D161 PolarHBondContact NE2-OD1 3.16Å; Q157-D161 WeakPolarHBondContact O-CB 3.45Å; Q157-D161 PolarHBondContact O-N 2.97Å; A158-D161 PolarHBondContact O-N 3.23Å; V159-D161 VanDerWaalsContact C-N 3.27Å; V159-D161 PolarHBondContact O-N 3.07Å
162V98.5Very high98Very high71 Ų7153 Ų5343%0.4326%0.256SS..Hα-helixtrans-105.7-9.8178.9-61.80000113.9V159 F160 T164 A503 M507V159-V162 VanDerWaalsContact O-CG2 3.25Å; V159-V162 WeakPolarHBondContact O-CG2 3.32Å; V159-V162 PolarHBondContact O-N 3.46Å; V159-V162 VanDerWaalsContact O-N 3.15Å; F160-V162 PolarHBondContact O-N 3.16Å; V162-T164 PolarHBondContact O-N 3.26Å; V162-A503 HydrophobicContact CG2-CB 3.92Å; V162-M507 HydrophobicContact CB-CE 4.12Å; V162-M507 HydrophobicContact CG1-CE 3.36Å; V162-M507 HydrophobicContact CG2-CE 3.64Å
163Y98.3Very high98Very high13 Ų1350.3 Ų50.35%0.05125%0.246CC..  trans-63.3126.2175.2-87.79.9000112.3V159 F160 I167 R168 D181 T500 A503 I504V159-Y163 HydrophobicContact CG1-CD1 3.8Å; V159-Y163 HydrophobicContact CG1-CD2 4.39Å; V159-Y163 HydrophobicContact CG1-CE1 3.25Å; V159-Y163 HydrophobicContact CG1-CE2 3.88Å; V159-Y163 HydrophobicContact CG1-CG 4.36Å; V159-Y163 WeakPolarHBondContact O-CD1 3.49Å; V159-Y163 PolarHBondContact O-N 2.86Å; V159-Y163 VanDerWaalsContact O-N 3.11Å; F160-Y163 HydrophobicContact CD1-CD2 4.28Å; F160-Y163 HydrophobicContact CE1-CD2 4.34Å; F160-Y163 PolarHBondContact O-N 3.2Å; Y163-I167 HydrophobicContact CD1-CD1 4.32Å; Y163-I167 HydrophobicContact CD1-CG2 3.87Å; Y163-I167 HydrophobicContact CD2-CG2 3.66Å; Y163-I167 HydrophobicContact CE1-CG2 3.95Å; Y163-I167 HydrophobicContact CE2-CG2 3.78Å; Y163-I167 HydrophobicContact CG-CB 4.44Å; Y163-I167 HydrophobicContact CG-CG2 3.7Å; Y163-R168 HydrophobicContact CD2-CG 4.45Å; Y163-R168 PolarHBondContact O-NE 2.96Å; Y163-D181 PolarHBondContact OH-OD2 3.22Å; Y163-T500 HydrophobicContact CE1-CG2 3.86Å; Y163-T500 VanDerWaalsContact OH-CG2 3.3Å; Y163-T500 WeakPolarHBondContact OH-CG2 3.28Å; Y163-A503 HydrophobicContact CD1-CB 4.43Å; Y163-A503 HydrophobicContact CE1-CB 4.24Å; Y163-I504 HydrophobicContact CE1-CG1 4.35Å; Y163-I504 VanDerWaalsContact OH-CD1 3.24Å; Y163-I504 WeakPolarHBondContact OH-CD1 3.3Å; Y163-I504 WeakPolarHBondContact OH-CG1 3.4Å
164T98.2Very high98Very high57 Ų5750 Ų5035%0.3525%0.245SC..  trans-72.6161.5174.679.40000111.4V162 E166 I167 R168V162-T164 PolarHBondContact O-N 3.26Å; T164-E166 WeakPolarHBondContact CB-OE2 3.43Å; T164-E166 PolarHBondContact O-N 3.49Å; T164-E166 PolarHBondContact OG1-N 2.94Å; T164-E166 PolarHBondContact OG1-OE2 3.48Å; T164-I167 HydrophobicContact CG2-CD1 4.38Å; T164-I167 PolarHBondContact O-N 3.37Å; T164-I167 PolarHBondContact OG1-N 2.77Å; T164-R168 WeakPolarHBondContact O-CG 3.23Å; T164-R168 PolarHBondContact O-N 2.77Å; T164-R168 VanDerWaalsContact O-N 3.11Å
165P97.8Very high98Very high98 Ų9849.8 Ų49.864%0.63624%0.244SC*.Hα-helixtrans-54.1-36.6172.2-26.836.8000113.4R168 A169P165-R168 PolarHBondContact O-N 3.25Å; P165-A169 WeakPolarHBondContact O-CB 3.35Å; P165-A169 PolarHBondContact O-N 3.13Å
166E97.6Very high97.9Very high106 Ų10650 Ų5050%0.49524%0.244SC..Hα-helixtrans-67.4-45.9-179.9-56.173.6-158.400111.4T164 R168 A169 A170 M496T164-E166 WeakPolarHBondContact CB-OE2 3.43Å; T164-E166 PolarHBondContact O-N 3.49Å; T164-E166 PolarHBondContact OG1-N 2.94Å; T164-E166 PolarHBondContact OG1-OE2 3.48Å; E166-R168 VanDerWaalsContact C-N 3.27Å; E166-R168 PolarHBondContact O-N 3.47Å; E166-A169 WeakPolarHBondContact O-CB 3.3Å; E166-A169 PolarHBondContact O-N 3.19Å; E166-A169 VanDerWaalsContact O-N 3.13Å; E166-A170 WeakPolarHBondContact O-CB 3.32Å; E166-A170 PolarHBondContact O-N 2.76Å; E166-M496 HydrophobicContact CB-CE 3.84Å
167I98.2Very high97.7Very high12 Ų1249.9 Ų49.96%0.06224%0.244CC..Hα-helixtrans-58.2-44174.4-67.8175000110.1Y163 T164 A169 A170 R171 M496 T500Y163-I167 HydrophobicContact CD1-CD1 4.32Å; Y163-I167 HydrophobicContact CD1-CG2 3.87Å; Y163-I167 HydrophobicContact CD2-CG2 3.66Å; Y163-I167 HydrophobicContact CE1-CG2 3.95Å; Y163-I167 HydrophobicContact CE2-CG2 3.78Å; Y163-I167 HydrophobicContact CG-CB 4.44Å; Y163-I167 HydrophobicContact CG-CG2 3.7Å; T164-I167 HydrophobicContact CG2-CD1 4.38Å; T164-I167 PolarHBondContact O-N 3.37Å; T164-I167 PolarHBondContact OG1-N 2.77Å; I167-A169 VanDerWaalsContact C-N 3.32Å; I167-A169 PolarHBondContact O-N 3.38Å; I167-A170 PolarHBondContact O-N 3.02Å; I167-R171 WeakPolarHBondContact O-CB 3.35Å; I167-R171 PolarHBondContact O-N 3.35Å; I167-M496 HydrophobicContact CB-SD 4.48Å; I167-M496 HydrophobicContact CG1-SD 3.76Å; I167-T500 WeakPolarHBondContact CG1-OG1 3.36Å; I167-T500 HydrophobicContact CG2-CG2 3.71Å
168R97.9Very high97.6Very high100 Ų10046.1 Ų46.138%0.37723%0.228SC..Hα-helixtrans-65-36.1178.3-68.7167.7175.7-95.38.2112F160 Y163 T164 P165 E166 R172F160-R168 PolarHBondContact O-NH2 3.4Å; Y163-R168 HydrophobicContact CD2-CG 4.45Å; Y163-R168 PolarHBondContact O-NE 2.96Å; T164-R168 WeakPolarHBondContact O-CG 3.23Å; T164-R168 PolarHBondContact O-N 2.77Å; T164-R168 VanDerWaalsContact O-N 3.11Å; P165-R168 PolarHBondContact O-N 3.25Å; E166-R168 VanDerWaalsContact C-N 3.27Å; E166-R168 PolarHBondContact O-N 3.47Å; R168-R172 WeakPolarHBondContact O-CB 3.36Å; R168-R172 PolarHBondContact O-N 3.25Å
169A97.8Very high97.5Very high34 Ų3446.3 Ų46.328%0.28123%0.229SC..Hα-helixtrans-67.5-48.517500000111.2P165 E166 I167 R171 R172 A173 V464P165-A169 WeakPolarHBondContact O-CB 3.35Å; P165-A169 PolarHBondContact O-N 3.13Å; E166-A169 WeakPolarHBondContact O-CB 3.3Å; E166-A169 PolarHBondContact O-N 3.19Å; E166-A169 VanDerWaalsContact O-N 3.13Å; I167-A169 VanDerWaalsContact C-N 3.32Å; I167-A169 PolarHBondContact O-N 3.38Å; A169-R171 VanDerWaalsContact C-N 3.32Å; A169-R171 PolarHBondContact O-N 3.13Å; A169-R172 WeakPolarHBondContact O-CB 3.38Å; A169-R172 PolarHBondContact O-N 3.06Å; A169-R172 VanDerWaalsContact O-N 3.09Å; A169-A173 WeakPolarHBondContact O-CB 3.22Å; A169-A173 PolarHBondContact O-N 3.04Å; A169-V464 HydrophobicContact CB-CG1 4.48Å
170A98.3Very high97.5Very high1 Ų146.3 Ų46.31%0.00823%0.229CC..Hα-helixtrans-59.4-41.5177.300000112.2E166 I167 A173 K174 I175 I176 M496E166-A170 WeakPolarHBondContact O-CB 3.32Å; E166-A170 PolarHBondContact O-N 2.76Å; I167-A170 PolarHBondContact O-N 3.02Å; A170-A173 PolarHBondContact O-N 2.91Å; A170-K174 PolarHBondContact O-N 2.95Å; A170-K174 VanDerWaalsContact O-N 3.15Å; A170-I175 HydrophobicContact CB-CG2 3.7Å; A170-I175 PolarHBondContact O-N 3.38Å; A170-I176 HydrophobicContact CB-CD1 3.96Å; A170-I176 HydrophobicContact CB-CG1 3.61Å; A170-M496 HydrophobicContact CB-CG 4.09Å; A170-M496 HydrophobicContact CB-SD 4.33Å
171R97.4Very high97.4Very high63 Ų6345.1 Ų45.124%0.23822%0.223CC..Hα-helixtrans-62.3-43.1173.1-172.1-176-173.3-79.32.9112.8I167 A169 K174 I176 D181I167-R171 WeakPolarHBondContact O-CB 3.35Å; I167-R171 PolarHBondContact O-N 3.35Å; A169-R171 VanDerWaalsContact C-N 3.32Å; A169-R171 PolarHBondContact O-N 3.13Å; R171-K174 PolarHBondContact O-N 2.88Å; R171-I176 VanDerWaalsContact CA-O 3.25Å; R171-I176 WeakPolarHBondContact CA-O 3.27Å; R171-D181 IonicContact CZ-OD1 2.66Å; R171-D181 IonicContact CZ-OD2 2.82Å; R171-D181 IonicContact NE-OD1 3Å; R171-D181 IonicContact NE-OD2 2.77Å; R171-D181 PolarHBondContact NE-OD2 3.26Å; R171-D181 IonicContact NH2-OD1 2.71Å; R171-D181 PolarHBondContact NH2-OD1 3.2Å; R171-D181 VanDerWaalsContact NH2-OD1 3.09Å; R171-D181 IonicContact NH2-OD2 2.8Å
172R96.9Very high97.2Very high207 Ų20741.8 Ų41.878%0.78121%0.206SC*.Hα-helixtrans-67.6-40.3179.7-170.1-175.7-54.3-94.5-1.4111.9R168 A169 K174R168-R172 WeakPolarHBondContact O-CB 3.36Å; R168-R172 PolarHBondContact O-N 3.25Å; A169-R172 WeakPolarHBondContact O-CB 3.38Å; A169-R172 PolarHBondContact O-N 3.06Å; A169-R172 VanDerWaalsContact O-N 3.09Å; R172-K174 PolarHBondContact O-N 2.76Å
173A97.6Very high97.1Very high13 Ų1338.8 Ų38.811%0.10719%0.187CC..THydrogen-bonded Turntrans-75.2-5.6177.700000113.6A169 A170 I175 K446 Y450 V464A169-A173 WeakPolarHBondContact O-CB 3.22Å; A169-A173 PolarHBondContact O-N 3.04Å; A170-A173 PolarHBondContact O-N 2.91Å; A173-I175 VanDerWaalsContact C-N 3.27Å; A173-I175 PolarHBondContact O-N 3.05Å; A173-K446 WeakPolarHBondContact O-CD 3.41Å; A173-K446 VanDerWaalsContact O-CE 3.26Å; A173-K446 WeakPolarHBondContact O-CE 3.36Å; A173-Y450 WeakPolarHBondContact CB-OH 3.27Å; A173-V464 HydrophobicContact CB-CB 4.37Å; A173-V464 HydrophobicContact CB-CG1 3.85Å; A173-V464 HydrophobicContact CB-CG2 3.81Å
174K97.4Very high97Very high66 Ų6638.1 Ų38.129%0.28719%0.185SC..THydrogen-bonded Turntrans58.440.4179.2-48.7-70.5177.51750111.7A170 R171 R172 T177 N443 Y619 A622A170-K174 PolarHBondContact O-N 2.95Å; A170-K174 VanDerWaalsContact O-N 3.15Å; R171-K174 PolarHBondContact O-N 2.88Å; R172-K174 PolarHBondContact O-N 2.76Å; K174-T177 HydrophobicContact CB-CG2 4.13Å; K174-T177 HydrophobicContact CD-CG2 3.47Å; K174-T177 VanDerWaalsContact CD-CG2 3.47Å; K174-T177 WeakPolarHBondContact CD-OG1 3.46Å; K174-T177 HydrophobicContact CG-CG2 4.43Å; K174-T177 PolarHBondContact NZ-OG1 2.76Å; K174-T177 VanDerWaalsContact NZ-OG1 3.11Å; K174-N443 PolarHBondContact O-ND2 3.19Å; K174-N443 VanDerWaalsContact O-ND2 3.1Å; K174-Y619 HydrophobicContact CB-CD1 4.02Å; K174-Y619 HydrophobicContact CB-CE1 4.14Å; K174-Y619 WeakPolarHBondContact O-CD1 3.21Å; K174-Y619 WeakPolarHBondContact O-CE1 3.33Å; K174-A622 HydrophobicContact CB-CB 3.47Å; K174-A622 VanDerWaalsContact CB-CB 3.47Å; K174-A622 HydrophobicContact CG-CB 3.65Å
175I98.1Very high97Very high0 Ų035.5 Ų35.50%017%0.168CC..SBendtrans-90.7-31.9164.7-162.5161.8000111.3A170 A173 N443 K446 A447 Y450 W492 L493A170-I175 HydrophobicContact CB-CG2 3.7Å; A170-I175 PolarHBondContact O-N 3.38Å; A173-I175 VanDerWaalsContact C-N 3.27Å; A173-I175 PolarHBondContact O-N 3.05Å; I175-N443 PolarHBondContact O-N 2.71Å; I175-K446 HydrophobicContact CB-CD 4.05Å; I175-K446 HydrophobicContact CD1-CG 4.29Å; I175-K446 HydrophobicContact CG1-CD 4.46Å; I175-K446 HydrophobicContact CG1-CG 4.4Å; I175-A447 HydrophobicContact CD1-CB 4.31Å; I175-Y450 HydrophobicContact CD1-CD2 3.58Å; I175-Y450 HydrophobicContact CD1-CE2 3.52Å; I175-Y450 HydrophobicContact CD1-CG 4.15Å; I175-W492 HydrophobicContact CD1-CH2 4.08Å; I175-W492 HydrophobicContact CD1-CZ3 3.67Å; I175-W492 HydrophobicContact CG2-CH2 4.19Å; I175-L493 HydrophobicContact CD1-CD1 4.47Å; I175-L493 HydrophobicContact CG1-CD1 3.98Å
176I96.8Very high97Very high3 Ų330.9 Ų30.92%0.01514%0.139CC..BIsolated β-bridgetrans-136.898.2164.844.8153.4000109.8A170 R171 L179 A442 L493 M496 Y497 T500A170-I176 HydrophobicContact CB-CD1 3.96Å; A170-I176 HydrophobicContact CB-CG1 3.61Å; R171-I176 VanDerWaalsContact CA-O 3.25Å; R171-I176 WeakPolarHBondContact CA-O 3.27Å; I176-L179 HydrophobicContact CB-CD1 4.31Å; I176-A442 HydrophobicContact CG2-CB 3.82Å; I176-L493 HydrophobicContact CG2-CD1 3.81Å; I176-M496 HydrophobicContact CD1-CG 3.66Å; I176-M496 HydrophobicContact CD1-SD 4.38Å; I176-M496 HydrophobicContact CG1-CG 4.33Å; I176-Y497 HydrophobicContact CG2-CD2 4.14Å; I176-Y497 HydrophobicContact CG2-CG 4.12Å; I176-T500 HydrophobicContact CD1-CG2 4.35Å; I176-T500 WeakPolarHBondContact CD1-OG1 3.32Å
177T94.9Very high97Very high3 Ų326 Ų262%0.01812%0.116CC..  trans-134.1160.3-178.3-167.40000111.5K174 L179 Y619K174-T177 HydrophobicContact CB-CG2 4.13Å; K174-T177 HydrophobicContact CD-CG2 3.47Å; K174-T177 VanDerWaalsContact CD-CG2 3.47Å; K174-T177 WeakPolarHBondContact CD-OG1 3.46Å; K174-T177 HydrophobicContact CG-CG2 4.43Å; K174-T177 PolarHBondContact NZ-OG1 2.76Å; K174-T177 VanDerWaalsContact NZ-OG1 3.11Å; T177-L179 PolarHBondContact O-N 3.29Å; T177-Y619 HydrophobicContact CG2-CD1 3.92Å; T177-Y619 HydrophobicContact CG2-CE1 3.18Å; T177-Y619 PolarHBondContact N-OH 3.19Å; T177-Y619 PolarHBondContact O-OH 2.87Å
178G94.4Very high97Very high4 Ų425.4 Ų25.44%0.04111%0.113CC..SBendtrans70.427.5178.300000112.5Y183 A440G178-Y183 PolarHBondContact O-OH 2.82Å; G178-A440 WeakPolarHBondContact O-CB 3.47Å
179L97.2Very high97Very high4 Ų420.7 Ų20.72%0.02110%0.095CC..  trans-71.8162.4168-83.262.1000109.2I176 T177 D181 Y183 G439 Y497 T500 L501 I504I176-L179 HydrophobicContact CB-CD1 4.31Å; T177-L179 PolarHBondContact O-N 3.29Å; L179-D181 PolarHBondContact O-N 3.01Å; L179-Y183 WeakPolarHBondContact O-CE1 3.34Å; L179-G439 WeakPolarHBondContact CG-O 3.23Å; L179-Y497 HydrophobicContact CD1-CE2 4.18Å; L179-Y497 HydrophobicContact CD2-CD2 4.19Å; L179-Y497 HydrophobicContact CD2-CE2 4.07Å; L179-Y497 HydrophobicContact CG-CE2 4.17Å; L179-T500 HydrophobicContact CD2-CG2 3.49Å; L179-T500 VanDerWaalsContact CD2-CG2 3.49Å; L179-L501 HydrophobicContact CD2-CD2 3.65Å; L179-L501 HydrophobicContact CD2-CG 4.27Å; L179-L501 HydrophobicContact CG-CD2 3.92Å; L179-I504 HydrophobicContact CB-CD1 3.61Å; L179-I504 HydrophobicContact CD2-CD1 3.98Å; L179-I504 HydrophobicContact CG-CD1 4.33Å
180P97.4Very high97Very high0 Ų019.1 Ų19.10%08%0.082CC..THydrogen-bonded Turntrans-75.753.5-177.525.3-24.9000113.3H155 Y183 R185 F438 I504H155-P180 PolarHBondContact NE2-O 3.28Å; P180-Y183 HydrophobicContact CB-CD2 4.24Å; P180-Y183 HydrophobicContact CB-CE2 3.67Å; P180-R185 HydrophobicContact CB-CB 4.04Å; P180-R185 HydrophobicContact CG-CB 4.21Å; P180-F438 HydrophobicContact CB-CD1 4.34Å; P180-F438 HydrophobicContact CG-CB 4.49Å; P180-F438 HydrophobicContact CG-CD1 4.04Å; P180-F438 WeakPolarHBondContact CG-O 3.42Å; P180-I504 HydrophobicContact CB-CG2 4.45Å; P180-I504 HydrophobicContact CG-CG2 3.99Å; P180-I504 VanDerWaalsContact O-CG2 3.3Å; P180-I504 WeakPolarHBondContact O-CG2 3.43Å
181D97Very high97Very high3 Ų319.3 Ų19.32%0.0168%0.083CC..THydrogen-bonded Turntrans-94.5-15.217564.219.8000113N156 V159 F160 Y163 R171 L179 I504N156-D181 PolarHBondContact ND2-O 2.76Å; V159-D181 HydrophobicContact CG1-CB 3.85Å; F160-D181 HydrophobicContact CE2-CB 4.1Å; Y163-D181 PolarHBondContact OH-OD2 3.22Å; R171-D181 IonicContact CZ-OD1 2.66Å; R171-D181 IonicContact CZ-OD2 2.82Å; R171-D181 IonicContact NE-OD1 3Å; R171-D181 IonicContact NE-OD2 2.77Å; R171-D181 PolarHBondContact NE-OD2 3.26Å; R171-D181 IonicContact NH2-OD1 2.71Å; R171-D181 PolarHBondContact NH2-OD1 3.2Å; R171-D181 VanDerWaalsContact NH2-OD1 3.09Å; R171-D181 IonicContact NH2-OD2 2.8Å; L179-D181 PolarHBondContact O-N 3.01Å; D181-I504 HydrophobicContact CB-CD1 4.16Å; D181-I504 HydrophobicContact CB-CG1 4.41Å
182T94.2Very high97.1Very high19 Ų1916.4 Ų16.412%0.1177%0.072CC..SBendtrans-124.37179.858.60000114.9M128M128-T182 HydrophobicContact CG-CG2 4.37Å; M128-T182 HydrophobicContact SD-CG2 4.09Å
183Y95.9Very high97.2Very high8 Ų86.6 Ų6.63%0.0314%0.035CC..SBendtrans-154.1164.9-179.755.4-90.6000109.6G178 L179 P180 A279 Y330 F334 F438G178-Y183 PolarHBondContact O-OH 2.82Å; L179-Y183 WeakPolarHBondContact O-CE1 3.34Å; P180-Y183 HydrophobicContact CB-CD2 4.24Å; P180-Y183 HydrophobicContact CB-CE2 3.67Å; Y183-A279 HydrophobicContact CD2-CB 4.02Å; Y183-A279 HydrophobicContact CE2-CB 3.76Å; Y183-Y330 AromaticContact CD1-CD2 3.63Å; Y183-Y330 HydrophobicContact CD1-CD2 3.63Å; Y183-Y330 AromaticContact CD1-CE2 3.95Å; Y183-Y330 HydrophobicContact CD1-CE2 3.95Å; Y183-Y330 HydrophobicContact CD2-CD2 4.36Å; Y183-Y330 AromaticContact CD2-CE2 3.84Å; Y183-Y330 HydrophobicContact CD2-CE2 3.84Å; Y183-Y330 HydrophobicContact CE1-CD2 4.18Å; Y183-Y330 HydrophobicContact CE1-CE2 4.37Å; Y183-Y330 HydrophobicContact CE2-CE2 4.31Å; Y183-Y330 AromaticContact CG-CD2 3.75Å; Y183-Y330 HydrophobicContact CG-CD2 3.75Å; Y183-Y330 AromaticContact CG-CE2 3.68Å; Y183-Y330 HydrophobicContact CG-CE2 3.68Å; Y183-F334 AromaticContact CE1-CE2 3.99Å; Y183-F334 HydrophobicContact CE1-CE2 3.99Å; Y183-F334 HydrophobicContact CE2-CE2 4.39Å; Y183-F334 HydrophobicContact CE2-CZ 4.48Å; Y183-F334 AromaticContact CZ-CE2 3.78Å; Y183-F334 AromaticContact CZ-CZ 3.98Å; Y183-F438 HydrophobicContact CE2-CD1 4.42Å; Y183-F438 HydrophobicContact CE2-CE1 4.14Å
184G96.8Very high97.2Very high0 Ų06.4 Ų6.40%03%0.032CC..BIsolated β-bridgetrans-62.5139.5177.300000111.7G186 N277 G278 A279 H508G184-G186 VanDerWaalsContact C-N 3.31Å; G184-G186 PolarHBondContact O-N 3.17Å; G184-N277 PolarHBondContact N-OD1 3.29Å; G184-G278 CarbonylContact O-C 3.54Å; G184-G278 VanDerWaalsContact O-CA 3.27Å; G184-G278 WeakPolarHBondContact O-CA 3.44Å; G184-A279 PolarHBondContact O-N 3.28Å; G184-H508 WeakPolarHBondContact CA-NE2 3.5Å
185R98Very high97.3Very high1 Ų13.2 Ų3.20%0.0042%0.018CC..  trans-63.7-33.7-174.764.7-174.7175.8-165.2-2.3113.5P180 F438 H508 D509 E514P180-R185 HydrophobicContact CB-CB 4.04Å; P180-R185 HydrophobicContact CG-CB 4.21Å; R185-F438 HydrophobicContact CB-CB 4.39Å; R185-F438 WeakPolarHBondContact O-CB 3.4Å; R185-F438 WeakPolarHBondContact O-CD1 3.4Å; R185-H508 PolarHBondContact N-NE2 2.9Å; R185-D509 IonicContact CZ-OD1 3.09Å; R185-D509 VanDerWaalsContact CZ-OD1 3.23Å; R185-D509 IonicContact NH1-OD1 3.95Å; R185-D509 PolarHBondContact NH1-OD1 2.65Å; R185-D509 IonicContact NH2-OD1 3.62Å; R185-D509 PolarHBondContact NH2-OD1 3.47Å; R185-E514 VanDerWaalsContact CG-OE1 3.24Å; R185-E514 WeakPolarHBondContact CG-OE1 3.41Å; R185-E514 IonicContact CZ-OE1 3.06Å; R185-E514 IonicContact CZ-OE2 2.74Å; R185-E514 IonicContact NE-OE1 2.96Å; R185-E514 PolarHBondContact NE-OE1 2.98Å; R185-E514 IonicContact NE-OE2 3.96Å; R185-E514 IonicContact NH2-OE1 3.91Å; R185-E514 PolarHBondContact NH2-OE1 2.78Å; R185-E514 IonicContact NH2-OE2 2.78Å; R185-E514 PolarHBondContact NH2-OE2 3.45Å
186G97Very high97.3Very high2 Ų23.2 Ų3.22%0.0212%0.018CC..  trans59.4-144.6-172.300000110.8G184 I188 A280G184-G186 VanDerWaalsContact C-N 3.31Å; G184-G186 PolarHBondContact O-N 3.17Å; G186-I188 PolarHBondContact O-N 3.29Å; G186-A280 WeakPolarHBondContact CA-O 3.27Å
187R97.6Very high97.4Very high2 Ų23.1 Ų3.11%0.0082%0.017CC..  trans58.434.8-177.5-66.5-62-155.985.10.3113.6C423 S427 Q436 F438 D668R187-C423 WeakPolarHBondContact CA-SG 3.42Å; R187-S427 VanDerWaalsContact NH1-CB 3.32Å; R187-S427 PolarHBondContact NH1-OG 3.25Å; R187-S427 PolarHBondContact NH2-OG 3.38Å; R187-Q436 HydrophobicContact CB-CB 4.13Å; R187-Q436 WeakPolarHBondContact CB-O 3.48Å; R187-Q436 PolarHBondContact O-N 3.44Å; R187-Q436 VanDerWaalsContact O-N 3.16Å; R187-Q436 PolarHBondContact O-OE1 3.38Å; R187-Q436 VanDerWaalsContact O-OE1 3.1Å; R187-F438 HydrophobicContact CB-CB 3.98Å; R187-F438 HydrophobicContact CG-CB 3.47Å; R187-F438 VanDerWaalsContact CG-CB 3.47Å; R187-F438 HydrophobicContact CG-CD2 3.59Å; R187-F438 HydrophobicContact CG-CG 3.66Å; R187-D668 IonicContact CZ-OD1 2.85Å; R187-D668 IonicContact CZ-OD2 2.72Å; R187-D668 IonicContact NH1-OD1 3.51Å; R187-D668 PolarHBondContact NH1-OD1 3.47Å; R187-D668 IonicContact NH1-OD2 3.66Å; R187-D668 PolarHBondContact NH1-OD2 3.21Å; R187-D668 IonicContact NH2-OD1 2.68Å; R187-D668 IonicContact NH2-OD2 3.64Å; R187-D668 PolarHBondContact NH2-OD2 3.32Å
188I98.3Very high97.6Very high0 Ų03 Ų30%02%0.017CC..  trans-127.9138.8174.8-59171.3000106.7G186 M435 E514 E517 L518 M521G186-I188 PolarHBondContact O-N 3.29Å; I188-M435 HydrophobicContact CD1-CE 3.65Å; I188-M435 HydrophobicContact CG1-CB 4.21Å; I188-M435 HydrophobicContact CG1-CE 3.76Å; I188-E514 HydrophobicContact CD1-CB 3.84Å; I188-E514 HydrophobicContact CD1-CG 3.68Å; I188-E517 HydrophobicContact CG2-CB 3.71Å; I188-E517 HydrophobicContact CG2-CG 4.5Å; I188-L518 HydrophobicContact CD1-CD2 4.43Å; I188-L518 HydrophobicContact CG2-CD2 4.15Å; I188-M521 HydrophobicContact CG2-SD 3.8Å
189V97.6Very high97.8Very high1 Ų12.9 Ų2.91%0.0062%0.015CC..  trans-127.896.2174.1-174.50000107Y192 C423 T429V189-Y192 HydrophobicContact CG1-CE2 4.41Å; V189-C423 HydrophobicContact CG2-CB 3.78Å; V189-C423 VanDerWaalsContact CG2-SG 3.59Å; V189-T429 HydrophobicContact CB-CG2 4.42Å; V189-T429 HydrophobicContact CG2-CG2 4.13Å
190G98Very high97.8Very high1 Ų12.7 Ų2.71%0.011%0.014CC..  trans-58.1141.5168.800000109.8Y192G190-Y192 PolarHBondContact N-OH 2.93Å; G190-Y192 WeakPolarHBondContact O-CD2 3.44Å; G190-Y192 WeakPolarHBondContact O-CE2 3.01Å; G190-Y192 PolarHBondContact O-N 3.01Å
191D98.8Very high97.8Very high5 Ų55.1 Ų5.13%0.0273%0.027CC..  trans-79.575.8175.9-173.34.6000109.3V33 R193 R194 T431 L520V33-D191 VanDerWaalsContact CG2-OD2 3.28Å; V33-D191 WeakPolarHBondContact CG2-OD2 3.4Å; D191-R193 PolarHBondContact O-N 3.15Å; D191-R193 WeakPolarHBondContact OD1-CB 3.42Å; D191-R193 IonicContact OD1-CZ 3.72Å; D191-R193 IonicContact OD1-NE 2.76Å; D191-R193 PolarHBondContact OD1-NE 3.27Å; D191-R193 IonicContact OD1-NH2 3.23Å; D191-R193 PolarHBondContact OD1-NH2 3.12Å; D191-R193 IonicContact OD2-NH2 2.75Å; D191-R194 HydrophobicContact CB-CG 3.94Å; D191-R194 WeakPolarHBondContact O-CB 3.36Å; D191-R194 VanDerWaalsContact O-CG 3.31Å; D191-R194 WeakPolarHBondContact O-CG 3.28Å; D191-R194 PolarHBondContact O-N 3.43Å; D191-R194 WeakPolarHBondContact OD2-CG 3.31Å; D191-R194 IonicContact OD2-CZ 3.62Å; D191-R194 IonicContact OD2-NE 2.7Å; D191-R194 PolarHBondContact OD2-NE 2.93Å; D191-R194 IonicContact OD2-NH2 3.41Å; D191-T431 HydrophobicContact CB-CG2 4.02Å; D191-L520 WeakPolarHBondContact CB-O 3.37Å; D191-L520 PolarHBondContact N-O 3.14Å
192Y98.9Very high97.8Very high2 Ų26.2 Ų6.21%0.0083%0.031CC..THydrogen-bonded Turntrans-60.4-21.9-172.9-46.5-65.6000113.2V189 G190 R194 V195 T265 Y269 A272 S282 I283 L520V189-Y192 HydrophobicContact CG1-CE2 4.41Å; G190-Y192 PolarHBondContact N-OH 2.93Å; G190-Y192 WeakPolarHBondContact O-CD2 3.44Å; G190-Y192 WeakPolarHBondContact O-CE2 3.01Å; G190-Y192 PolarHBondContact O-N 3.01Å; Y192-R194 PolarHBondContact O-N 2.87Å; Y192-V195 WeakPolarHBondContact O-CB 3.42Å; Y192-V195 PolarHBondContact O-N 3.36Å; Y192-V195 VanDerWaalsContact O-N 3.13Å; Y192-T265 WeakPolarHBondContact CB-O 3.35Å; Y192-Y269 HydrophobicContact CD2-CD2 4.23Å; Y192-Y269 HydrophobicContact CE1-CD2 4.38Å; Y192-Y269 AromaticContact CE2-CD2 3.69Å; Y192-Y269 HydrophobicContact CE2-CD2 3.69Å; Y192-Y269 HydrophobicContact CE2-CG 4.49Å; Y192-Y269 AromaticContact CZ-CD2 3.77Å; Y192-A272 HydrophobicContact CE1-CB 4.05Å; Y192-S282 WeakPolarHBondContact CE2-O 3.47Å; Y192-S282 PolarHBondContact OH-O 3.24Å; Y192-I283 HydrophobicContact CD2-CG1 4.16Å; Y192-I283 VanDerWaalsContact CD2-O 3.26Å; Y192-I283 WeakPolarHBondContact CD2-O 3.42Å; Y192-I283 WeakPolarHBondContact CE2-O 3.38Å; Y192-L520 HydrophobicContact CD1-CD1 3.68Å; Y192-L520 HydrophobicContact CE1-CD1 4.3Å
193R98.9Very high98Very high2 Ų25.4 Ų5.41%0.0083%0.026CC..Hα-helixtrans-59.8-27.5173.1-54.4172.9-64.9178.516.4112.2V33 I37 D191 V195 A196 L197 R285 V286 F289 D419V33-R193 HydrophobicContact CG1-CB 3.96Å; I37-R193 VanDerWaalsContact CD1-NH1 3.32Å; D191-R193 PolarHBondContact O-N 3.15Å; D191-R193 WeakPolarHBondContact OD1-CB 3.42Å; D191-R193 IonicContact OD1-CZ 3.72Å; D191-R193 IonicContact OD1-NE 2.76Å; D191-R193 PolarHBondContact OD1-NE 3.27Å; D191-R193 IonicContact OD1-NH2 3.23Å; D191-R193 PolarHBondContact OD1-NH2 3.12Å; D191-R193 IonicContact OD2-NH2 2.75Å; R193-V195 PolarHBondContact O-N 2.96Å; R193-A196 PolarHBondContact O-N 3.47Å; R193-L197 PolarHBondContact O-N 3.23Å; R193-R285 WeakPolarHBondContact CD-O 3.42Å; R193-R285 PolarHBondContact NH1-O 2.97Å; R193-V286 HydrophobicContact CG-CG1 3.97Å; R193-F289 HydrophobicContact CB-CD1 3.74Å; R193-F289 HydrophobicContact CB-CD2 4.09Å; R193-F289 HydrophobicContact CB-CE1 3.67Å; R193-F289 HydrophobicContact CB-CE2 4.02Å; R193-F289 HydrophobicContact CB-CG 3.96Å; R193-F289 HydrophobicContact CB-CZ 3.82Å; R193-F289 HydrophobicContact CG-CB 4.25Å; R193-F289 HydrophobicContact CG-CD1 3.57Å; R193-F289 HydrophobicContact CG-CD2 4.39Å; R193-F289 HydrophobicContact CG-CE1 3.99Å; R193-F289 HydrophobicContact CG-CG 3.8Å; R193-F289 WeakPolarHBondContact O-CZ 3.24Å; R193-D419 IonicContact CZ-OD1 3.8Å; R193-D419 IonicContact CZ-OD2 2.84Å; R193-D419 IonicContact NH1-OD1 2.94Å; R193-D419 PolarHBondContact NH1-OD1 3.43Å; R193-D419 IonicContact NH1-OD2 3.04Å; R193-D419 IonicContact NH2-OD1 2.78Å; R193-D419 PolarHBondContact NH2-OD1 3.33Å; R193-D419 IonicContact NH2-OD2 3.9Å; R193-D419 PolarHBondContact NH2-OD2 3.04Å
194R98.8Very high98.2Very high8 Ų85.7 Ų5.73%0.033%0.028CC..Hα-helixtrans-58.8-35.8175.8-68.8178.9-174.9-157-1.3111.9I31 V33 D191 Y192 A196 L197 Y198 L203 G432 L520 M521 D522I31-R194 HydrophobicContact CG2-CG 4.02Å; I31-R194 VanDerWaalsContact CG2-CZ 3.41Å; V33-R194 HydrophobicContact CG2-CG 3.72Å; D191-R194 HydrophobicContact CB-CG 3.94Å; D191-R194 WeakPolarHBondContact O-CB 3.36Å; D191-R194 VanDerWaalsContact O-CG 3.31Å; D191-R194 WeakPolarHBondContact O-CG 3.28Å; D191-R194 PolarHBondContact O-N 3.43Å; D191-R194 WeakPolarHBondContact OD2-CG 3.31Å; D191-R194 IonicContact OD2-CZ 3.62Å; D191-R194 IonicContact OD2-NE 2.7Å; D191-R194 PolarHBondContact OD2-NE 2.93Å; D191-R194 IonicContact OD2-NH2 3.41Å; Y192-R194 PolarHBondContact O-N 2.87Å; R194-A196 VanDerWaalsContact C-N 3.35Å; R194-L197 PolarHBondContact O-N 2.9Å; R194-Y198 HydrophobicContact CB-CD2 4.17Å; R194-Y198 HydrophobicContact CG-CD2 4.4Å; R194-Y198 HydrophobicContact CG-CE2 4.49Å; R194-Y198 WeakPolarHBondContact O-CB 3.06Å; R194-Y198 WeakPolarHBondContact O-CD2 3.38Å; R194-Y198 PolarHBondContact O-N 3.25Å; R194-L203 HydrophobicContact CB-CD1 4.02Å; R194-L203 HydrophobicContact CB-CD2 4.02Å; R194-G432 PolarHBondContact NH2-O 3.06Å; R194-L520 WeakPolarHBondContact CD-O 3.22Å; R194-L520 PolarHBondContact NE-O 3.28Å; R194-M521 VanDerWaalsContact NH1-C 3.28Å; R194-D522 IonicContact CZ-OD1 3.73Å; R194-D522 IonicContact NH1-OD1 3.36Å; R194-D522 PolarHBondContact NH1-OD1 2.87Å; R194-D522 VanDerWaalsContact NH1-OD1 3.14Å; R194-D522 IonicContact NH2-OD1 2.84Å; R194-D522 PolarHBondContact NH2-OD1 3.01Å
195V98.9Very high98.2Very high0 Ų010.1 Ų10.10%05%0.049CC..Hα-helixtrans-62.8-46178.3-174.40000109.8Y192 R193 G199 I200 I251 W264 L520Y192-V195 WeakPolarHBondContact O-CB 3.42Å; Y192-V195 PolarHBondContact O-N 3.36Å; Y192-V195 VanDerWaalsContact O-N 3.13Å; R193-V195 PolarHBondContact O-N 2.96Å; V195-G199 VanDerWaalsContact O-CA 3.31Å; V195-G199 WeakPolarHBondContact O-CA 3.25Å; V195-G199 PolarHBondContact O-N 2.91Å; V195-I200 HydrophobicContact CG1-CD1 4.02Å; V195-I200 HydrophobicContact CG1-CG1 4.32Å; V195-I200 HydrophobicContact CG2-CD1 4.26Å; V195-I251 HydrophobicContact CG1-CD1 4.15Å; V195-W264 HydrophobicContact CG1-CB 4.07Å; V195-W264 HydrophobicContact CG1-CG 4.48Å; V195-W264 WeakPolarHBondContact CG1-O 3.41Å; V195-L520 HydrophobicContact CG2-CD1 4.04Å; V195-L520 HydrophobicContact CG2-CD2 3.71Å
196A98.8Very high98.2Very high0 Ų011.6 Ų11.60%06%0.055CC..Hα-helixtrans-66.4-46.4176.300000112.6R193 R194 A255 A261 W264 T265 F289R193-A196 PolarHBondContact O-N 3.47Å; R194-A196 VanDerWaalsContact C-N 3.35Å; A196-A255 HydrophobicContact CB-CB 4.24Å; A196-A255 WeakPolarHBondContact O-CB 3.47Å; A196-A255 PolarHBondContact O-N 3.3Å; A196-A261 HydrophobicContact CB-CB 4.38Å; A196-A261 WeakPolarHBondContact CB-O 3.44Å; A196-W264 HydrophobicContact CB-CB 3.85Å; A196-T265 WeakPolarHBondContact CB-OG1 3.2Å; A196-F289 HydrophobicContact CB-CE1 3.91Å; A196-F289 HydrophobicContact CB-CZ 3.87Å
197L98.6Very high98.2Very high0 Ų011.8 Ų11.80%06%0.056CC..Hα-helixtrans-71.1-38.1-173.4-174.956.7000113.2W19 W27 V33 F36 R193 R194 P254 F289W19-L197 PolarHBondContact NE1-O 3.23Å; W27-L197 HydrophobicContact CE3-CD1 3.92Å; W27-L197 HydrophobicContact CE3-CD2 4.29Å; W27-L197 HydrophobicContact CE3-CG 4.31Å; W27-L197 HydrophobicContact CH2-CD1 4.41Å; W27-L197 HydrophobicContact CZ3-CD1 3.66Å; W27-L197 HydrophobicContact CZ3-CG 4.41Å; V33-L197 HydrophobicContact CG2-CD2 4.13Å; F36-L197 HydrophobicContact CB-CD1 4.47Å; F36-L197 HydrophobicContact CB-CD2 3.61Å; F36-L197 HydrophobicContact CD1-CD1 3.98Å; F36-L197 HydrophobicContact CD1-CD2 3.96Å; F36-L197 HydrophobicContact CD2-CD1 3.63Å; F36-L197 HydrophobicContact CD2-CD2 4.32Å; F36-L197 HydrophobicContact CE1-CD1 4.06Å; F36-L197 HydrophobicContact CE2-CD1 3.71Å; F36-L197 HydrophobicContact CG-CD1 3.75Å; F36-L197 HydrophobicContact CG-CD2 3.7Å; F36-L197 HydrophobicContact CG-CG 4.41Å; F36-L197 HydrophobicContact CZ-CD1 3.91Å; R193-L197 PolarHBondContact O-N 3.23Å; R194-L197 PolarHBondContact O-N 2.9Å; L197-P254 VanDerWaalsContact O-CB 3.29Å; L197-P254 WeakPolarHBondContact O-CB 3.41Å; L197-F289 HydrophobicContact CB-CE2 4.18Å; L197-F289 HydrophobicContact CB-CZ 4.23Å
198Y98.2Very high98.2Very high2 Ų215 Ų151%0.0087%0.073CC..Hα-helixtrans-114-26.4-169.5-62.1-70.6000114.5W19 W27 E30 I31 N32 V33 R194 Y202 L203 P254W19-Y198 HydrophobicContact CH2-CD1 4.49Å; W19-Y198 HydrophobicContact CZ2-CD1 4.08Å; W19-Y198 HydrophobicContact CZ2-CE1 4.45Å; W27-Y198 WeakPolarHBondContact O-CE1 3.24Å; W27-Y198 PolarHBondContact O-OH 2.95Å; E30-Y198 PolarHBondContact O-OH 2.9Å; E30-Y198 VanDerWaalsContact O-OH 3.09Å; I31-Y198 HydrophobicContact CB-CE2 4.38Å; I31-Y198 HydrophobicContact CG2-CD2 4.43Å; I31-Y198 HydrophobicContact CG2-CE2 3.89Å; N32-Y198 PolarHBondContact N-OH 3.37Å; V33-Y198 HydrophobicContact CG2-CE2 4.14Å; R194-Y198 HydrophobicContact CB-CD2 4.17Å; R194-Y198 HydrophobicContact CG-CD2 4.4Å; R194-Y198 HydrophobicContact CG-CE2 4.49Å; R194-Y198 WeakPolarHBondContact O-CB 3.06Å; R194-Y198 WeakPolarHBondContact O-CD2 3.38Å; R194-Y198 PolarHBondContact O-N 3.25Å; Y198-Y202 AromaticContact CD1-CD1 3.83Å; Y198-Y202 HydrophobicContact CD1-CD1 3.83Å; Y198-Y202 AromaticContact CD1-CE1 3.79Å; Y198-Y202 HydrophobicContact CD1-CE1 3.79Å; Y198-Y202 HydrophobicContact CD1-CG 4.39Å; Y198-Y202 HydrophobicContact CE1-CE1 4.28Å; Y198-Y202 AromaticContact CG-CD1 3.99Å; Y198-Y202 HydrophobicContact CG-CD1 3.99Å; Y198-Y202 HydrophobicContact CG-CE1 4.28Å; Y198-Y202 WeakPolarHBondContact O-CB 3.25Å; Y198-L203 HydrophobicContact CD2-CD2 4.13Å; Y198-L203 HydrophobicContact CG-CD2 4.32Å; Y198-P254 WeakPolarHBondContact O-CD 3.14Å
199G98Very high98.2Very high0 Ų020.2 Ų20.20%010%0.095CC..  trans74.7158.9-167.300000112.9V195 D201 L203 R253V195-G199 VanDerWaalsContact O-CA 3.31Å; V195-G199 WeakPolarHBondContact O-CA 3.25Å; V195-G199 PolarHBondContact O-N 2.91Å; G199-D201 PolarHBondContact O-N 3.16Å; G199-L203 WeakPolarHBondContact O-CG 3.26Å; G199-L203 PolarHBondContact O-N 2.73Å; G199-R253 VanDerWaalsContact CA-C 3.44Å; G199-R253 WeakPolarHBondContact CA-O 3.32Å
200I98.5Very high98.1Very high0 Ų022.5 Ų22.50%011%0.108CC..Hα-helixtrans-66-37.2-173.8-68-63.8000112.6V195 Y202 L203 M204 L237 I240 K241 I251 S252V195-I200 HydrophobicContact CG1-CD1 4.02Å; V195-I200 HydrophobicContact CG1-CG1 4.32Å; V195-I200 HydrophobicContact CG2-CD1 4.26Å; I200-Y202 PolarHBondContact O-N 2.99Å; I200-L203 PolarHBondContact O-N 3.12Å; I200-M204 HydrophobicContact CG2-CG 3.96Å; I200-M204 HydrophobicContact CG2-SD 3.58Å; I200-M204 VanDerWaalsContact CG2-SD 3.58Å; I200-M204 WeakPolarHBondContact O-CB 3.23Å; I200-M204 VanDerWaalsContact O-CG 3.3Å; I200-M204 WeakPolarHBondContact O-CG 3.43Å; I200-M204 PolarHBondContact O-N 3.06Å; I200-L237 HydrophobicContact CD1-CD2 4.03Å; I200-L237 HydrophobicContact CG2-CB 4.17Å; I200-L237 WeakPolarHBondContact CG2-O 3.36Å; I200-I240 HydrophobicContact CD1-CB 4.15Å; I200-I240 HydrophobicContact CD1-CG2 4.19Å; I200-K241 HydrophobicContact CB-CB 4.45Å; I200-K241 HydrophobicContact CG1-CB 4.47Å; I200-K241 HydrophobicContact CG2-CB 4.06Å; I200-K241 HydrophobicContact CG2-CD 4.45Å; I200-I251 HydrophobicContact CD1-CD1 4.18Å; I200-I251 HydrophobicContact CG1-CD1 3.54Å; I200-I251 HydrophobicContact CG1-CG1 3.72Å; I200-I251 PolarHBondContact N-O 3.05Å; I200-S252 PolarHBondContact N-O 2.97Å
201D98Very high98Very high52 Ų5224.9 Ų24.928%0.27812%0.119SC..Hα-helixtrans-68.5-38.1-173.9-77.47.7000111.6M11 G199 M204 Q205 K241 S252M11-D201 HydrophobicContact CE-CB 4.46Å; G199-D201 PolarHBondContact O-N 3.16Å; D201-M204 PolarHBondContact O-N 3.47Å; D201-Q205 WeakPolarHBondContact O-CG 3.4Å; D201-Q205 PolarHBondContact O-N 3.33Å; D201-Q205 VanDerWaalsContact O-N 3.07Å; D201-K241 IonicContact OD1-NZ 2.66Å; D201-K241 PolarHBondContact OD1-NZ 3.1Å; D201-K241 IonicContact OD2-NZ 3.81Å; D201-S252 WeakPolarHBondContact CB-O 3.48Å; D201-S252 PolarHBondContact N-O 2.54Å; D201-S252 VanDerWaalsContact N-O 3.09Å
202Y97Very high97.7Very high25 Ų2528.2 Ų28.210%0.09815%0.147CC..Hα-helixtrans-61-49.3172.8-175.3-82000111I31 Y198 I200 M204 Q205 E206I31-Y202 HydrophobicContact CG1-CE1 3.91Å; Y198-Y202 AromaticContact CD1-CD1 3.83Å; Y198-Y202 HydrophobicContact CD1-CD1 3.83Å; Y198-Y202 AromaticContact CD1-CE1 3.79Å; Y198-Y202 HydrophobicContact CD1-CE1 3.79Å; Y198-Y202 HydrophobicContact CD1-CG 4.39Å; Y198-Y202 HydrophobicContact CE1-CE1 4.28Å; Y198-Y202 AromaticContact CG-CD1 3.99Å; Y198-Y202 HydrophobicContact CG-CD1 3.99Å; Y198-Y202 HydrophobicContact CG-CE1 4.28Å; Y198-Y202 WeakPolarHBondContact O-CB 3.25Å; I200-Y202 PolarHBondContact O-N 2.99Å; Y202-M204 VanDerWaalsContact C-N 3.31Å; Y202-M204 PolarHBondContact O-N 3.03Å; Y202-Q205 PolarHBondContact O-N 2.75Å; Y202-Q205 VanDerWaalsContact O-N 3.1Å; Y202-E206 HydrophobicContact CD1-CG 3.94Å; Y202-E206 HydrophobicContact CE1-CG 3.55Å; Y202-E206 PolarHBondContact O-N 2.87Å
203L98.4Very high97.4Very high3 Ų334 Ų342%0.01618%0.178CC..Hα-helixtrans-61.5-38.4180-61.5174.8000112.3I31 R194 Y198 G199 I200 E206 K207 L237 L520I31-L203 HydrophobicContact CD1-CD2 3.64Å; I31-L203 HydrophobicContact CG1-CD2 4.23Å; R194-L203 HydrophobicContact CB-CD1 4.02Å; R194-L203 HydrophobicContact CB-CD2 4.02Å; Y198-L203 HydrophobicContact CD2-CD2 4.13Å; Y198-L203 HydrophobicContact CG-CD2 4.32Å; G199-L203 WeakPolarHBondContact O-CG 3.26Å; G199-L203 PolarHBondContact O-N 2.73Å; I200-L203 PolarHBondContact O-N 3.12Å; L203-E206 PolarHBondContact O-N 3.39Å; L203-K207 PolarHBondContact O-N 3.48Å; L203-L237 HydrophobicContact CB-CD1 4.01Å; L203-L237 HydrophobicContact CB-CD2 4.34Å; L203-L237 HydrophobicContact CD1-CD2 4.44Å; L203-L520 HydrophobicContact CD1-CD2 3.84Å
204M98.5Very high97.1Very high13 Ų1334.6 Ų34.66%0.06418%0.182CC..Hα-helixtrans-63.9-39.7174.9-75.2179.370.100111.9I200 D201 Y202 K207 L208 Y234 L237 K238I200-M204 HydrophobicContact CG2-CG 3.96Å; I200-M204 HydrophobicContact CG2-SD 3.58Å; I200-M204 VanDerWaalsContact CG2-SD 3.58Å; I200-M204 WeakPolarHBondContact O-CB 3.23Å; I200-M204 VanDerWaalsContact O-CG 3.3Å; I200-M204 WeakPolarHBondContact O-CG 3.43Å; I200-M204 PolarHBondContact O-N 3.06Å; D201-M204 PolarHBondContact O-N 3.47Å; Y202-M204 VanDerWaalsContact C-N 3.31Å; Y202-M204 PolarHBondContact O-N 3.03Å; M204-K207 PolarHBondContact O-N 2.95Å; M204-L208 WeakPolarHBondContact O-CG 3.43Å; M204-L208 PolarHBondContact O-N 3.18Å; M204-L208 VanDerWaalsContact O-N 3.08Å; M204-Y234 HydrophobicContact CB-CD2 4.06Å; M204-Y234 HydrophobicContact CB-CE2 3.76Å; M204-Y234 HydrophobicContact CE-CD1 4.26Å; M204-Y234 HydrophobicContact CE-CD2 4.1Å; M204-Y234 HydrophobicContact CE-CE1 3.65Å; M204-Y234 HydrophobicContact CE-CE2 3.48Å; M204-Y234 VanDerWaalsContact CE-CE2 3.48Å; M204-Y234 HydrophobicContact CE-CG 4.46Å; M204-Y234 WeakPolarHBondContact CE-OH 3.37Å; M204-Y234 HydrophobicContact CG-CD2 4.32Å; M204-Y234 HydrophobicContact CG-CE2 4.24Å; M204-L237 HydrophobicContact CB-CD1 4.49Å; M204-L237 HydrophobicContact CG-CB 3.56Å; M204-L237 HydrophobicContact CG-CD1 3.8Å; M204-L237 HydrophobicContact CG-CG 4.33Å; M204-L237 HydrophobicContact SD-CB 4.23Å; M204-K238 HydrophobicContact CE-CB 4.02Å; M204-K238 HydrophobicContact SD-CB 4.41Å
205Q97.8Very high96.2Very high94 Ų9435.3 Ų35.344%0.43919%0.192SC..Hα-helixtrans-66.3-40.1175.5-68.3-62-17.700112D201 Y202 L208 K209D201-Q205 WeakPolarHBondContact O-CG 3.4Å; D201-Q205 PolarHBondContact O-N 3.33Å; D201-Q205 VanDerWaalsContact O-N 3.07Å; Y202-Q205 PolarHBondContact O-N 2.75Å; Y202-Q205 VanDerWaalsContact O-N 3.1Å; Q205-L208 PolarHBondContact O-N 2.75Å; Q205-K209 WeakPolarHBondContact O-CG 3.27Å; Q205-K209 PolarHBondContact O-N 2.77Å
206E97.5Very high95.2Very high31 Ų3144 Ų4415%0.14523%0.232CC..Hα-helixtrans-62.3-42.5174.7-65.2-51.8109.100111.6I31 Y202 L203 L208 K209 D210I31-E206 HydrophobicContact CD1-CB 3.82Å; I31-E206 HydrophobicContact CD1-CG 3.78Å; I31-E206 HydrophobicContact CG1-CG 4.08Å; Y202-E206 HydrophobicContact CD1-CG 3.94Å; Y202-E206 HydrophobicContact CE1-CG 3.55Å; Y202-E206 PolarHBondContact O-N 2.87Å; L203-E206 PolarHBondContact O-N 3.39Å; E206-L208 VanDerWaalsContact C-N 3.31Å; E206-L208 PolarHBondContact O-N 2.71Å; E206-K209 WeakPolarHBondContact O-CB 3.12Å; E206-K209 PolarHBondContact O-N 2.95Å; E206-K209 VanDerWaalsContact O-N 3.07Å; E206-K209 WeakPolarHBondContact OE1-CE 3.32Å; E206-K209 IonicContact OE1-NZ 2.64Å; E206-K209 PolarHBondContact OE1-NZ 3.36Å; E206-K209 IonicContact OE2-NZ 3.85Å; E206-D210 PolarHBondContact O-N 2.79Å
207K98Very high94.2Very high6 Ų647.9 Ų47.93%0.02627%0.273CS..Hα-helixtrans-64-33.4175-69.1-66.2173.71790113.4L203 M204 D210 H211 I230 Q233 L237 A519 M521 T523L203-K207 PolarHBondContact O-N 3.48Å; M204-K207 PolarHBondContact O-N 2.95Å; K207-D210 PolarHBondContact O-N 3.09Å; K207-H211 WeakPolarHBondContact O-CB 3.4Å; K207-H211 PolarHBondContact O-N 3.47Å; K207-I230 HydrophobicContact CB-CG2 4.22Å; K207-I230 HydrophobicContact CD-CG2 4.33Å; K207-I230 VanDerWaalsContact O-CG2 3.25Å; K207-I230 WeakPolarHBondContact O-CG2 3.29Å; K207-Q233 VanDerWaalsContact CE-OE1 3.24Å; K207-L237 HydrophobicContact CG-CD1 4.03Å; K207-A519 WeakPolarHBondContact CE-O 3.33Å; K207-M521 PolarHBondContact NZ-O 2.93Å; K207-T523 PolarHBondContact NZ-OG1 3.08Å; K207-T523 VanDerWaalsContact NZ-OG1 3.14Å
208L97.7Very high93.3Very high71 Ų7154.7 Ų54.737%0.37230%0.304SS..Hα-helixtrans-66.2-38171.8-71.7175.1000112.2M204 Q205 E206 H211 A212 Y234M204-L208 WeakPolarHBondContact O-CG 3.43Å; M204-L208 PolarHBondContact O-N 3.18Å; M204-L208 VanDerWaalsContact O-N 3.08Å; Q205-L208 PolarHBondContact O-N 2.75Å; E206-L208 VanDerWaalsContact C-N 3.31Å; E206-L208 PolarHBondContact O-N 2.71Å; L208-H211 PolarHBondContact O-N 3.27Å; L208-A212 WeakPolarHBondContact O-CB 3.49Å; L208-A212 PolarHBondContact O-N 3.18Å; L208-Y234 HydrophobicContact CD1-CD2 4.46Å; L208-Y234 HydrophobicContact CD1-CE2 3.67Å; L208-Y234 HydrophobicContact CD2-CD2 3.93Å; L208-Y234 HydrophobicContact CD2-CE2 3.79Å; L208-Y234 HydrophobicContact CG-CD2 3.83Å; L208-Y234 HydrophobicContact CG-CE2 3.54Å
209K96.6Very high92.8Very high108 Ų10860.3 Ų60.347%0.4733%0.329SS..Hα-helixtrans-64.5-45173.9-67.3172.8-173.8171.90111Q205 E206 H211 A212 N213Q205-K209 WeakPolarHBondContact O-CG 3.27Å; Q205-K209 PolarHBondContact O-N 2.77Å; E206-K209 WeakPolarHBondContact O-CB 3.12Å; E206-K209 PolarHBondContact O-N 2.95Å; E206-K209 VanDerWaalsContact O-N 3.07Å; E206-K209 WeakPolarHBondContact OE1-CE 3.32Å; E206-K209 IonicContact OE1-NZ 2.64Å; E206-K209 PolarHBondContact OE1-NZ 3.36Å; E206-K209 IonicContact OE2-NZ 3.85Å; K209-H211 VanDerWaalsContact C-N 3.34Å; K209-H211 PolarHBondContact O-N 2.62Å; K209-A212 WeakPolarHBondContact O-CB 3.41Å; K209-A212 PolarHBondContact O-N 3Å; K209-A212 VanDerWaalsContact O-N 3.11Å; K209-N213 PolarHBondContact O-N 3.01Å; K209-N213 PolarHBondContact O-ND2 3.37Å
210D95.7Very high92.6Very high50 Ų5062.4 Ų62.427%0.26734%0.342SS..Hα-helixtrans-58.6-46.4176.1-71.6-15.3000111.4E206 K207 A212 N213 C214 I230 T523E206-D210 PolarHBondContact O-N 2.79Å; K207-D210 PolarHBondContact O-N 3.09Å; D210-A212 VanDerWaalsContact C-N 3.29Å; D210-A212 PolarHBondContact O-N 3.46Å; D210-N213 PolarHBondContact O-N 3.05Å; D210-N213 VanDerWaalsContact O-N 3.11Å; D210-C214 WeakPolarHBondContact O-CB 3.33Å; D210-C214 PolarHBondContact O-N 3.43Å; D210-I230 HydrophobicContact CB-CD1 4.37Å; D210-T523 HydrophobicContact CB-CG2 4.2Å; D210-T523 VanDerWaalsContact CG-OG1 3.3Å; D210-T523 WeakPolarHBondContact OD2-CB 3.45Å; D210-T523 PolarHBondContact OD2-OG1 3.42Å
211H95.8Very high92.4Very high51 Ų5168.9 Ų68.924%0.23637%0.372CS..Hα-helixtrans-61.5-36.1175.6-177.7-100.9000112.5K207 L208 K209 N213 R227 I230K207-H211 WeakPolarHBondContact O-CB 3.4Å; K207-H211 PolarHBondContact O-N 3.47Å; L208-H211 PolarHBondContact O-N 3.27Å; K209-H211 VanDerWaalsContact C-N 3.34Å; K209-H211 PolarHBondContact O-N 2.62Å; H211-N213 VanDerWaalsContact C-N 3.32Å; H211-R227 PolarHBondContact CD2-O 3.3Å; H211-R227 PolarHBondContact CE1-NH2 3.48Å; H211-R227 PolarHBondContact NE2-NH2 2.88Å; H211-R227 VanDerWaalsContact NE2-NH2 3.17Å; H211-R227 PolarHBondContact O-NH1 3.02Å; H211-I230 HydrophobicContact CB-CB 4.48Å; H211-I230 HydrophobicContact CB-CG2 3.78Å
212A94.1Very high92.2Very high75 Ų7571.5 Ų71.562%0.6238%0.383SS*.Hα-helixtrans-69.3-29.717600000112.8L208 K209 D210L208-A212 WeakPolarHBondContact O-CB 3.49Å; L208-A212 PolarHBondContact O-N 3.18Å; K209-A212 WeakPolarHBondContact O-CB 3.41Å; K209-A212 PolarHBondContact O-N 3Å; K209-A212 VanDerWaalsContact O-N 3.11Å; D210-A212 VanDerWaalsContact C-N 3.29Å; D210-A212 PolarHBondContact O-N 3.46Å
213N91.7Very high92Very high122 Ų12272.1 Ų72.165%0.65239%0.388SS*.Hα-helixtrans-90.5-13.8-178.6-68.8-34.9000114.1K209 D210 H211K209-N213 PolarHBondContact O-N 3.01Å; K209-N213 PolarHBondContact O-ND2 3.37Å; D210-N213 PolarHBondContact O-N 3.05Å; D210-N213 VanDerWaalsContact O-N 3.11Å; H211-N213 VanDerWaalsContact C-N 3.32Å
214C91.6Very high91.8Very high16 Ų1676 Ų7611%0.10841%0.408CS..THydrogen-bonded Turntrans-79.9122179.9-174.60000112.2D210 R227 I230D210-C214 WeakPolarHBondContact O-CB 3.33Å; D210-C214 PolarHBondContact O-N 3.43Å; C214-R227 HydrophobicContact CB-CG 3.82Å; C214-R227 PolarHBondContact O-NH1 2.97Å; C214-R227 VanDerWaalsContact SG-CG 3.59Å; C214-I230 HydrophobicContact CB-CD1 4.17Å
215G81.3Confident91.7Very high22 Ų2277.6 Ų77.623%0.22741%0.413CS..THydrogen-bonded Turntrans89.729.2176.500000116.1G217 Q218G215-G217 PolarHBondContact O-N 3.31Å; G215-G217 VanDerWaalsContact O-N 3.16Å; G215-Q218 CarbonylContact C-O 3.44Å
216H77.5Confident91.7Very high182 Ų18274.2 Ų74.284%0.84340%0.398SS*.SBendtrans-74.7104.8-178.8-172.3-74.6000112.7
217G78.2Confident91.6Very high83 Ų8375.8 Ų75.886%0.85640%0.402SS*.SBendtrans93.7-14.7171.500000115.2G215G215-G217 PolarHBondContact O-N 3.31Å; G215-G217 VanDerWaalsContact O-N 3.16Å
218Q78.7Confident91.6Very high142 Ų14281.6 Ų81.666%0.66443%0.429SS*.  trans-146.3138.1172-171.9172-20.100108.3G215 T220G215-Q218 CarbonylContact C-O 3.44Å; Q218-T220 HydrophobicContact CG-CG2 3.99Å
219F87.9Confident91.6Very high120 Ų12078.7 Ų78.753%0.52641%0.414SS..  trans-127.181.5-175.1-155.1-141.2000110.1D223 I224 R227F219-D223 HydrophobicContact CD2-CB 3.66Å; F219-D223 HydrophobicContact CE2-CB 3.91Å; F219-I224 HydrophobicContact CD1-CD1 4.16Å; F219-I224 HydrophobicContact CD1-CG1 3.75Å; F219-I224 HydrophobicContact CD2-CG1 4.12Å; F219-I224 HydrophobicContact CE1-CD1 4.16Å; F219-I224 HydrophobicContact CE1-CG1 3.41Å; F219-I224 VanDerWaalsContact CE1-CG1 3.41Å; F219-I224 HydrophobicContact CE2-CB 4.46Å; F219-I224 HydrophobicContact CE2-CG1 3.73Å; F219-I224 HydrophobicContact CG-CG1 4.1Å; F219-I224 HydrophobicContact CZ-CB 4.2Å; F219-I224 HydrophobicContact CZ-CG1 3.38Å; F219-R227 HydrophobicContact CE2-CG 4.43Å
220T93.5Very high91.7Very high45 Ų4573.6 Ų73.628%0.27639%0.392SS..  trans-79.5170.3178.6690000111.3Q218 E222 D223 I224Q218-T220 HydrophobicContact CG-CG2 3.99Å; T220-E222 PolarHBondContact O-N 3.4Å; T220-E222 PolarHBondContact OG1-N 2.87Å; T220-D223 WeakPolarHBondContact CB-OD2 3.26Å; T220-D223 PolarHBondContact N-OD2 3.33Å; T220-D223 PolarHBondContact O-N 3.4Å; T220-D223 PolarHBondContact OG1-N 2.61Å; T220-D223 PolarHBondContact OG1-OD2 3.1Å; T220-I224 WeakPolarHBondContact O-CG1 3.33Å; T220-I224 PolarHBondContact O-N 2.94Å
221E94.1Very high91.8Very high135 Ų13573.1 Ų73.163%0.63139%0.392SS*.Hα-helixtrans-57.1-35.3171.4-174.8179.5164.600111.8I224 R225E221-I224 PolarHBondContact O-N 3.12Å; E221-R225 WeakPolarHBondContact O-CB 3.33Å; E221-R225 PolarHBondContact O-N 3.28Å
222E93.6Very high92Very high108 Ų10873.1 Ų73.151%0.50539%0.394SS..Hα-helixtrans-67-41.8177.5-54.5-168.6146.700111.8T220 L226T220-E222 PolarHBondContact O-N 3.4Å; T220-E222 PolarHBondContact OG1-N 2.87Å; E222-L226 WeakPolarHBondContact O-CB 3.27Å; E222-L226 PolarHBondContact O-N 3.03Å
223D93.6Very high92.2Very high38 Ų3869.7 Ų69.720%0.20337%0.365CS..Hα-helixtrans-64.9-41.3175.8-60-66.6000111.5F219 T220 L226 R227F219-D223 HydrophobicContact CD2-CB 3.66Å; F219-D223 HydrophobicContact CE2-CB 3.91Å; T220-D223 WeakPolarHBondContact CB-OD2 3.26Å; T220-D223 PolarHBondContact N-OD2 3.33Å; T220-D223 PolarHBondContact O-N 3.4Å; T220-D223 PolarHBondContact OG1-N 2.61Å; T220-D223 PolarHBondContact OG1-OD2 3.1Å; D223-L226 PolarHBondContact O-N 3.11Å; D223-R227 VanDerWaalsContact O-CG 3.28Å; D223-R227 WeakPolarHBondContact O-CG 3.24Å; D223-R227 PolarHBondContact O-N 2.92Å
224I95Very high92.5Very high84 Ų8467.4 Ų67.443%0.43135%0.348SS..Hα-helixtrans-62.5-50.8178.1-68.3161.6000110F219 T220 E221 L226 R227 E228F219-I224 HydrophobicContact CD1-CD1 4.16Å; F219-I224 HydrophobicContact CD1-CG1 3.75Å; F219-I224 HydrophobicContact CD2-CG1 4.12Å; F219-I224 HydrophobicContact CE1-CD1 4.16Å; F219-I224 HydrophobicContact CE1-CG1 3.41Å; F219-I224 VanDerWaalsContact CE1-CG1 3.41Å; F219-I224 HydrophobicContact CE2-CB 4.46Å; F219-I224 HydrophobicContact CE2-CG1 3.73Å; F219-I224 HydrophobicContact CG-CG1 4.1Å; F219-I224 HydrophobicContact CZ-CB 4.2Å; F219-I224 HydrophobicContact CZ-CG1 3.38Å; T220-I224 WeakPolarHBondContact O-CG1 3.33Å; T220-I224 PolarHBondContact O-N 2.94Å; E221-I224 PolarHBondContact O-N 3.12Å; I224-L226 PolarHBondContact O-N 2.91Å; I224-R227 PolarHBondContact O-N 3.26Å; I224-E228 PolarHBondContact O-N 3.36Å; I224-E228 VanDerWaalsContact O-N 3.14Å
225R96.3Very high92.9Very high46 Ų4671.7 Ų71.717%0.17437%0.365CS..Hα-helixtrans-57.9-48.7177.6177.9176.360-137.2-5.7111.1E221 R227 E228 E229E221-R225 WeakPolarHBondContact O-CB 3.33Å; E221-R225 PolarHBondContact O-N 3.28Å; R225-R227 VanDerWaalsContact C-N 3.31Å; R225-R227 PolarHBondContact O-N 3.27Å; R225-E228 WeakPolarHBondContact O-CB 3.31Å; R225-E228 PolarHBondContact O-N 2.88Å; R225-E229 HydrophobicContact CG-CG 4.34Å; R225-E229 WeakPolarHBondContact O-CB 3.17Å; R225-E229 VanDerWaalsContact O-CG 3.31Å; R225-E229 WeakPolarHBondContact O-CG 3.49Å; R225-E229 PolarHBondContact O-N 3.03Å
226L96.3Very high93.7Very high23 Ų2370.7 Ų70.712%0.1235%0.354CS..Hα-helixtrans-62.8-36.7-178.2-176.757.2000112.3E222 D223 I224 E229 I230 T523E222-L226 WeakPolarHBondContact O-CB 3.27Å; E222-L226 PolarHBondContact O-N 3.03Å; D223-L226 PolarHBondContact O-N 3.11Å; I224-L226 PolarHBondContact O-N 2.91Å; L226-E229 WeakPolarHBondContact O-CB 3.48Å; L226-E229 PolarHBondContact O-N 2.85Å; L226-I230 HydrophobicContact CD1-CD1 4.39Å; L226-I230 HydrophobicContact CD1-CG1 4.34Å; L226-I230 HydrophobicContact CG-CD1 4.04Å; L226-I230 HydrophobicContact CG-CG1 4.49Å; L226-I230 WeakPolarHBondContact O-CD1 3.48Å; L226-I230 WeakPolarHBondContact O-CG1 3.26Å; L226-I230 PolarHBondContact O-N 2.66Å; L226-T523 HydrophobicContact CD1-CG2 4.04Å; L226-T523 HydrophobicContact CD2-CG2 4.25Å; L226-T523 HydrophobicContact CG-CG2 4.32Å
227R96.7Very high94.7Very high65 Ų6562 Ų6225%0.24531%0.314CS..Hα-helixtrans-67.5-37.8175.5-71.9172.671.479.811.3113.4H211 C214 F219 D223 I224 R225 S231H211-R227 PolarHBondContact CD2-O 3.3Å; H211-R227 PolarHBondContact CE1-NH2 3.48Å; H211-R227 PolarHBondContact NE2-NH2 2.88Å; H211-R227 VanDerWaalsContact NE2-NH2 3.17Å; H211-R227 PolarHBondContact O-NH1 3.02Å; C214-R227 HydrophobicContact CB-CG 3.82Å; C214-R227 PolarHBondContact O-NH1 2.97Å; C214-R227 VanDerWaalsContact SG-CG 3.59Å; F219-R227 HydrophobicContact CE2-CG 4.43Å; D223-R227 VanDerWaalsContact O-CG 3.28Å; D223-R227 WeakPolarHBondContact O-CG 3.24Å; D223-R227 PolarHBondContact O-N 2.92Å; I224-R227 PolarHBondContact O-N 3.26Å; R225-R227 VanDerWaalsContact C-N 3.31Å; R225-R227 PolarHBondContact O-N 3.27Å; R227-S231 WeakPolarHBondContact O-CB 3.44Å; R227-S231 PolarHBondContact O-N 3.29Å; R227-S231 PolarHBondContact O-OG 3.21Å
228E97.8Very high95.7Very high127 Ų12763.1 Ų63.159%0.59330%0.295SS*.Hα-helixtrans-62.8-48.7172.8-178.1172.3-139.900110.2I224 R225 I230 S231 D232I224-E228 PolarHBondContact O-N 3.36Å; I224-E228 VanDerWaalsContact O-N 3.14Å; R225-E228 WeakPolarHBondContact O-CB 3.31Å; R225-E228 PolarHBondContact O-N 2.88Å; E228-I230 PolarHBondContact O-N 3.12Å; E228-S231 WeakPolarHBondContact O-CA 3.48Å; E228-S231 VanDerWaalsContact O-CB 3.32Å; E228-S231 WeakPolarHBondContact O-CB 3.12Å; E228-S231 PolarHBondContact O-N 3.28Å; E228-D232 PolarHBondContact O-N 3.2Å
229E98.4Very high96.6Very high10 Ų1059.2 Ų59.25%0.04727%0.274CS..Hα-helixtrans-54.4-48.6175.3-73.4174.6169.500111.9R225 L226 S231 D232 Q233 Y513 R602R225-E229 HydrophobicContact CG-CG 4.34Å; R225-E229 WeakPolarHBondContact O-CB 3.17Å; R225-E229 VanDerWaalsContact O-CG 3.31Å; R225-E229 WeakPolarHBondContact O-CG 3.49Å; R225-E229 PolarHBondContact O-N 3.03Å; L226-E229 WeakPolarHBondContact O-CB 3.48Å; L226-E229 PolarHBondContact O-N 2.85Å; E229-S231 VanDerWaalsContact C-N 3.29Å; E229-S231 PolarHBondContact O-N 3.46Å; E229-D232 PolarHBondContact O-N 2.95Å; E229-Q233 VanDerWaalsContact O-CG 3.24Å; E229-Q233 WeakPolarHBondContact O-CG 3.3Å; E229-Q233 PolarHBondContact O-N 2.98Å; E229-Y513 HydrophobicContact CB-CE1 4.03Å; E229-Y513 HydrophobicContact CB-CE2 4.23Å; E229-Y513 WeakPolarHBondContact CB-OH 3.24Å; E229-Y513 HydrophobicContact CG-CD2 4.17Å; E229-Y513 HydrophobicContact CG-CE1 4.09Å; E229-Y513 HydrophobicContact CG-CE2 3.59Å; E229-R602 IonicContact OE1-CZ 3.24Å; E229-R602 IonicContact OE1-NH1 2.76Å; E229-R602 PolarHBondContact OE1-NH1 2.86Å; E229-R602 IonicContact OE1-NH2 3.15Å; E229-R602 PolarHBondContact OE1-NH2 3.12Å; E229-R602 VanDerWaalsContact OE1-NH2 3.15Å; E229-R602 IonicContact OE2-CZ 3.67Å; E229-R602 IonicContact OE2-NH1 2.65Å; E229-R602 IonicContact OE2-NH2 2.86Å; E229-R602 PolarHBondContact OE2-NH2 3Å
230I98.3Very high97.2Very high2 Ų253.5 Ų53.51%0.0125%0.249CC..Hα-helixtrans-62.8-36.6177.2-62.4158.7000111.5K207 D210 H211 C214 L226 E228 D232 Q233 Y234 T523K207-I230 HydrophobicContact CB-CG2 4.22Å; K207-I230 HydrophobicContact CD-CG2 4.33Å; K207-I230 VanDerWaalsContact O-CG2 3.25Å; K207-I230 WeakPolarHBondContact O-CG2 3.29Å; D210-I230 HydrophobicContact CB-CD1 4.37Å; H211-I230 HydrophobicContact CB-CB 4.48Å; H211-I230 HydrophobicContact CB-CG2 3.78Å; C214-I230 HydrophobicContact CB-CD1 4.17Å; L226-I230 HydrophobicContact CD1-CD1 4.39Å; L226-I230 HydrophobicContact CD1-CG1 4.34Å; L226-I230 HydrophobicContact CG-CD1 4.04Å; L226-I230 HydrophobicContact CG-CG1 4.49Å; L226-I230 WeakPolarHBondContact O-CD1 3.48Å; L226-I230 WeakPolarHBondContact O-CG1 3.26Å; L226-I230 PolarHBondContact O-N 2.66Å; E228-I230 PolarHBondContact O-N 3.12Å; I230-D232 VanDerWaalsContact C-N 3.31Å; I230-D232 PolarHBondContact O-N 3.19Å; I230-Q233 WeakPolarHBondContact O-CB 3.47Å; I230-Q233 PolarHBondContact O-N 3.13Å; I230-Y234 PolarHBondContact O-N 3.46Å; I230-T523 HydrophobicContact CD1-CG2 3.52Å; I230-T523 HydrophobicContact CG1-CG2 3.78Å
231S98.5Very high97.4Very high39 Ų3954.1 Ų54.127%0.27325%0.248SC..Hα-helixtrans-65.3-37.8177-62.60000111.5R227 E228 E229 K235R227-S231 WeakPolarHBondContact O-CB 3.44Å; R227-S231 PolarHBondContact O-N 3.29Å; R227-S231 PolarHBondContact O-OG 3.21Å; E228-S231 WeakPolarHBondContact O-CA 3.48Å; E228-S231 VanDerWaalsContact O-CB 3.32Å; E228-S231 WeakPolarHBondContact O-CB 3.12Å; E228-S231 PolarHBondContact O-N 3.28Å; E229-S231 VanDerWaalsContact C-N 3.29Å; E229-S231 PolarHBondContact O-N 3.46Å; S231-K235 WeakPolarHBondContact O-CG 3.11Å; S231-K235 PolarHBondContact O-N 3.42Å; S231-K235 VanDerWaalsContact O-N 3.16Å
232D98.6Very high97.6Very high51 Ų5151.5 Ų51.527%0.27324%0.236SC..Hα-helixtrans-73.4-36.7176.1-73.1-17.4000112.3E228 E229 I230 Y234 K235 A236 A515E228-D232 PolarHBondContact O-N 3.2Å; E229-D232 PolarHBondContact O-N 2.95Å; I230-D232 VanDerWaalsContact C-N 3.31Å; I230-D232 PolarHBondContact O-N 3.19Å; D232-Y234 PolarHBondContact O-N 2.86Å; D232-K235 PolarHBondContact O-N 2.86Å; D232-K235 IonicContact OD1-NZ 2.75Å; D232-K235 PolarHBondContact OD1-NZ 3.41Å; D232-A236 WeakPolarHBondContact O-CB 3.26Å; D232-A236 PolarHBondContact O-N 3.19Å; D232-A515 HydrophobicContact CB-CB 4.27Å
233Q98.8Very high97.8Very high3 Ų346.5 Ų46.51%0.01421%0.213CC..Hα-helixtrans-58.4-45.2169.9-70.5170.819.800111.7K207 E229 I230 K235 A236 L237 Y513 L518 A519K207-Q233 VanDerWaalsContact CE-OE1 3.24Å; E229-Q233 VanDerWaalsContact O-CG 3.24Å; E229-Q233 WeakPolarHBondContact O-CG 3.3Å; E229-Q233 PolarHBondContact O-N 2.98Å; I230-Q233 WeakPolarHBondContact O-CB 3.47Å; I230-Q233 PolarHBondContact O-N 3.13Å; Q233-K235 VanDerWaalsContact C-N 3.34Å; Q233-K235 PolarHBondContact O-N 2.69Å; Q233-A236 WeakPolarHBondContact O-CB 3.5Å; Q233-A236 PolarHBondContact O-N 2.69Å; Q233-A236 VanDerWaalsContact O-N 3.16Å; Q233-L237 WeakPolarHBondContact O-CG 3.12Å; Q233-L237 PolarHBondContact O-N 3Å; Q233-Y513 HydrophobicContact CG-CE1 4.28Å; Q233-Y513 PolarHBondContact NE2-OH 2.9Å; Q233-L518 HydrophobicContact CG-CB 4.4Å; Q233-A519 HydrophobicContact CB-CB 3.65Å; Q233-A519 HydrophobicContact CG-CB 4.04Å
234Y98.7Very high98.1Very high75 Ų7544.7 Ų44.729%0.29420%0.203SC..Hα-helixtrans-60-43.4176177.6-87.5000112.1M204 L208 I230 D232 A236 L237 K238M204-Y234 HydrophobicContact CB-CD2 4.06Å; M204-Y234 HydrophobicContact CB-CE2 3.76Å; M204-Y234 HydrophobicContact CE-CD1 4.26Å; M204-Y234 HydrophobicContact CE-CD2 4.1Å; M204-Y234 HydrophobicContact CE-CE1 3.65Å; M204-Y234 HydrophobicContact CE-CE2 3.48Å; M204-Y234 VanDerWaalsContact CE-CE2 3.48Å; M204-Y234 HydrophobicContact CE-CG 4.46Å; M204-Y234 WeakPolarHBondContact CE-OH 3.37Å; M204-Y234 HydrophobicContact CG-CD2 4.32Å; M204-Y234 HydrophobicContact CG-CE2 4.24Å; L208-Y234 HydrophobicContact CD1-CD2 4.46Å; L208-Y234 HydrophobicContact CD1-CE2 3.67Å; L208-Y234 HydrophobicContact CD2-CD2 3.93Å; L208-Y234 HydrophobicContact CD2-CE2 3.79Å; L208-Y234 HydrophobicContact CG-CD2 3.83Å; L208-Y234 HydrophobicContact CG-CE2 3.54Å; I230-Y234 PolarHBondContact O-N 3.46Å; D232-Y234 PolarHBondContact O-N 2.86Å; Y234-A236 VanDerWaalsContact C-N 3.33Å; Y234-L237 PolarHBondContact O-N 3.04Å; Y234-K238 PolarHBondContact O-N 2.73Å
235K98.7Very high98.2Very high106 Ų10643.6 Ų43.646%0.46121%0.207SC..Hα-helixtrans-65-38175.4-66.2168.4-157.1156.70111.4S231 D232 Q233 K238 R239S231-K235 WeakPolarHBondContact O-CG 3.11Å; S231-K235 PolarHBondContact O-N 3.42Å; S231-K235 VanDerWaalsContact O-N 3.16Å; D232-K235 PolarHBondContact O-N 2.86Å; D232-K235 IonicContact OD1-NZ 2.75Å; D232-K235 PolarHBondContact OD1-NZ 3.41Å; Q233-K235 VanDerWaalsContact C-N 3.34Å; Q233-K235 PolarHBondContact O-N 2.69Å; K235-K238 WeakPolarHBondContact O-CB 3.41Å; K235-K238 PolarHBondContact O-N 3.04Å; K235-R239 PolarHBondContact O-N 3.29Å; K235-R239 VanDerWaalsContact O-N 3.08Å
236A98.7Very high98.3Very high0 Ų043.8 Ų43.80%022%0.218CC..Hα-helixtrans-61.6-49.7177.300000110.9D232 Q233 Y234 K238 R239 I240 A515 A516D232-A236 WeakPolarHBondContact O-CB 3.26Å; D232-A236 PolarHBondContact O-N 3.19Å; Q233-A236 WeakPolarHBondContact O-CB 3.5Å; Q233-A236 PolarHBondContact O-N 2.69Å; Q233-A236 VanDerWaalsContact O-N 3.16Å; Y234-A236 VanDerWaalsContact C-N 3.33Å; A236-K238 PolarHBondContact O-N 3Å; A236-R239 CarbonylContact O-C 3.54Å; A236-R239 WeakPolarHBondContact O-CA 3.29Å; A236-R239 WeakPolarHBondContact O-CB 3.19Å; A236-R239 PolarHBondContact O-N 2.84Å; A236-I240 WeakPolarHBondContact O-CG1 3.45Å; A236-I240 PolarHBondContact O-N 3.28Å; A236-A515 HydrophobicContact CB-CB 3.87Å; A236-A516 HydrophobicContact CB-CB 4.4Å
237L98.9Very high98.4Very high0 Ų043.4 Ų43.40%022%0.215CC..Hα-helixtrans-52.3-42.4174.9-69.6172.4000112.4I200 L203 M204 K207 Q233 Y234 R239 I240 K241 A519 L520I200-L237 HydrophobicContact CD1-CD2 4.03Å; I200-L237 HydrophobicContact CG2-CB 4.17Å; I200-L237 WeakPolarHBondContact CG2-O 3.36Å; L203-L237 HydrophobicContact CB-CD1 4.01Å; L203-L237 HydrophobicContact CB-CD2 4.34Å; L203-L237 HydrophobicContact CD1-CD2 4.44Å; M204-L237 HydrophobicContact CB-CD1 4.49Å; M204-L237 HydrophobicContact CG-CB 3.56Å; M204-L237 HydrophobicContact CG-CD1 3.8Å; M204-L237 HydrophobicContact CG-CG 4.33Å; M204-L237 HydrophobicContact SD-CB 4.23Å; K207-L237 HydrophobicContact CG-CD1 4.03Å; Q233-L237 WeakPolarHBondContact O-CG 3.12Å; Q233-L237 PolarHBondContact O-N 3Å; Y234-L237 PolarHBondContact O-N 3.04Å; L237-R239 PolarHBondContact O-N 3.34Å; L237-I240 HydrophobicContact CD2-CD1 4.43Å; L237-I240 WeakPolarHBondContact O-CB 3.21Å; L237-I240 PolarHBondContact O-N 3.02Å; L237-K241 PolarHBondContact O-N 3.08Å; L237-A519 HydrophobicContact CD1-CB 4.37Å; L237-A519 HydrophobicContact CD2-CB 3.97Å; L237-A519 HydrophobicContact CG-CB 3.82Å; L237-L520 HydrophobicContact CD2-CD2 3.84Å
238K98.6Very high98.5Very high106 Ų10643.7 Ų43.746%0.46124%0.238SC..Hα-helixtrans-60.8-43.3174.7-173.8-178.9174.9-169.90112.3M204 Y234 K235 A236 I240 K241 E242M204-K238 HydrophobicContact CE-CB 4.02Å; M204-K238 HydrophobicContact SD-CB 4.41Å; Y234-K238 PolarHBondContact O-N 2.73Å; K235-K238 WeakPolarHBondContact O-CB 3.41Å; K235-K238 PolarHBondContact O-N 3.04Å; A236-K238 PolarHBondContact O-N 3Å; K238-I240 VanDerWaalsContact C-N 3.33Å; K238-I240 PolarHBondContact O-N 3.43Å; K238-K241 PolarHBondContact O-N 3.46Å; K238-E242 WeakPolarHBondContact CE-OE1 3.49Å; K238-E242 IonicContact NZ-OE1 4Å; K238-E242 WeakPolarHBondContact O-CG 3.36Å; K238-E242 PolarHBondContact O-N 3.12Å; K238-E242 VanDerWaalsContact O-N 3.07Å
239R98.5Very high98.5Very high60 Ų6039.7 Ų39.723%0.22622%0.219CC..Hα-helixtrans-63.8-35.4175.5-66.1-170.6-61.8-91.64.4112.4A89 K235 A236 L237 K241 E242 M243 E275A89-R239 HydrophobicContact CB-CB 4.12Å; K235-R239 PolarHBondContact O-N 3.29Å; K235-R239 VanDerWaalsContact O-N 3.08Å; A236-R239 CarbonylContact O-C 3.54Å; A236-R239 WeakPolarHBondContact O-CA 3.29Å; A236-R239 WeakPolarHBondContact O-CB 3.19Å; A236-R239 PolarHBondContact O-N 2.84Å; L237-R239 PolarHBondContact O-N 3.34Å; R239-K241 VanDerWaalsContact C-N 3.31Å; R239-K241 PolarHBondContact O-N 3.33Å; R239-E242 PolarHBondContact O-N 2.78Å; R239-M243 WeakPolarHBondContact O-CB 3.36Å; R239-M243 PolarHBondContact O-N 3.01Å; R239-E275 IonicContact CZ-OE1 3.34Å; R239-E275 IonicContact CZ-OE2 3.86Å; R239-E275 IonicContact NE-OE1 2.74Å; R239-E275 PolarHBondContact NE-OE1 3.42Å; R239-E275 IonicContact NE-OE2 4Å; R239-E275 IonicContact NH2-OE1 3.1Å; R239-E275 PolarHBondContact NH2-OE1 3.43Å; R239-E275 VanDerWaalsContact NH2-OE1 3.1Å; R239-E275 IonicContact NH2-OE2 2.88Å; R239-E275 PolarHBondContact NH2-OE2 3.36Å
240I98.8Very high98.5Very high0 Ų043.9 Ų43.90%024%0.242CC..Hα-helixtrans-60.3-44.2174.5-49.5-170.8000110.1I200 A236 L237 K238 M243 A244 I251 A271I200-I240 HydrophobicContact CD1-CB 4.15Å; I200-I240 HydrophobicContact CD1-CG2 4.19Å; A236-I240 WeakPolarHBondContact O-CG1 3.45Å; A236-I240 PolarHBondContact O-N 3.28Å; L237-I240 HydrophobicContact CD2-CD1 4.43Å; L237-I240 WeakPolarHBondContact O-CB 3.21Å; L237-I240 PolarHBondContact O-N 3.02Å; K238-I240 VanDerWaalsContact C-N 3.33Å; K238-I240 PolarHBondContact O-N 3.43Å; I240-M243 HydrophobicContact CG2-CE 4.12Å; I240-M243 WeakPolarHBondContact O-CB 3.48Å; I240-M243 PolarHBondContact O-N 2.87Å; I240-A244 PolarHBondContact O-N 3.23Å; I240-I251 HydrophobicContact CG2-CD1 3.8Å; I240-A271 HydrophobicContact CB-CB 4.37Å; I240-A271 HydrophobicContact CD1-CB 3.79Å; I240-A271 HydrophobicContact CG1-CB 3.59Å; I240-A271 HydrophobicContact CG2-CB 4.22Å
241K98.3Very high98.5Very high58 Ų5843.8 Ų43.825%0.25224%0.241SC..Hα-helixtrans-62.5-42.9176.4-174.5167.164.3178.60112.5I200 D201 L237 K238 R239 A244 A245 I251I200-K241 HydrophobicContact CB-CB 4.45Å; I200-K241 HydrophobicContact CG1-CB 4.47Å; I200-K241 HydrophobicContact CG2-CB 4.06Å; I200-K241 HydrophobicContact CG2-CD 4.45Å; D201-K241 IonicContact OD1-NZ 2.66Å; D201-K241 PolarHBondContact OD1-NZ 3.1Å; D201-K241 IonicContact OD2-NZ 3.81Å; L237-K241 PolarHBondContact O-N 3.08Å; K238-K241 PolarHBondContact O-N 3.46Å; R239-K241 VanDerWaalsContact C-N 3.31Å; R239-K241 PolarHBondContact O-N 3.33Å; K241-A244 PolarHBondContact O-N 3.48Å; K241-A245 WeakPolarHBondContact O-CB 3.13Å; K241-A245 PolarHBondContact O-N 2.56Å; K241-I251 HydrophobicContact CB-CG1 4.4Å; K241-I251 HydrophobicContact CG-CG1 4.42Å
242E98.5Very high98.5Very high80 Ų8043.1 Ų43.137%0.37424%0.236SC..Hα-helixtrans-64-40.5175.9-69168.9-176.700112.1N90 K238 R239 A245 A246N90-E242 HydrophobicContact CB-CB 4.19Å; N90-E242 PolarHBondContact ND2-OE2 3.46Å; K238-E242 WeakPolarHBondContact CE-OE1 3.49Å; K238-E242 IonicContact NZ-OE1 4Å; K238-E242 WeakPolarHBondContact O-CG 3.36Å; K238-E242 PolarHBondContact O-N 3.12Å; K238-E242 VanDerWaalsContact O-N 3.07Å; R239-E242 PolarHBondContact O-N 2.78Å; E242-A245 PolarHBondContact O-N 3.47Å; E242-A246 PolarHBondContact O-N 3.15Å
243M98.7Very high98.4Very high4 Ų443.2 Ų43.22%0.0223%0.233CC..Hα-helixtrans-60.8-50.4175.2178.1-173.569.400111.6A89 R239 I240 A245 A246 F267 L270 A271 K274A89-M243 HydrophobicContact CB-SD 4.22Å; A89-M243 VanDerWaalsContact O-CB 3.32Å; A89-M243 WeakPolarHBondContact O-CB 3.29Å; A89-M243 WeakPolarHBondContact O-CG 3.4Å; R239-M243 WeakPolarHBondContact O-CB 3.36Å; R239-M243 PolarHBondContact O-N 3.01Å; I240-M243 HydrophobicContact CG2-CE 4.12Å; I240-M243 WeakPolarHBondContact O-CB 3.48Å; I240-M243 PolarHBondContact O-N 2.87Å; M243-A245 VanDerWaalsContact C-N 3.29Å; M243-A245 PolarHBondContact O-N 3.21Å; M243-A246 WeakPolarHBondContact O-CB 3.49Å; M243-A246 PolarHBondContact O-N 2.76Å; M243-F267 HydrophobicContact CE-CB 4.18Å; M243-F267 HydrophobicContact CE-CD1 4.03Å; M243-F267 HydrophobicContact CE-CG 4.5Å; M243-F267 WeakPolarHBondContact CE-O 3.1Å; M243-L270 HydrophobicContact CE-CB 4.06Å; M243-L270 HydrophobicContact CE-CD2 4.03Å; M243-L270 HydrophobicContact CE-CG 4.16Å; M243-L270 HydrophobicContact SD-CB 4.39Å; M243-L270 HydrophobicContact SD-CD2 3.79Å; M243-L270 HydrophobicContact SD-CG 3.87Å; M243-A271 HydrophobicContact CE-CB 3.95Å; M243-A271 HydrophobicContact SD-CB 4.46Å; M243-K274 HydrophobicContact SD-CD 3.54Å; M243-K274 VanDerWaalsContact SD-CD 3.54Å
244A98.8Very high98.3Very high0 Ų043.3 Ų43.30%023%0.234CC..Hα-helixtrans-64.6-34.8-179.900000112.3I240 K241 A246 Y247 G248 F249 I251 F267I240-A244 PolarHBondContact O-N 3.23Å; K241-A244 PolarHBondContact O-N 3.48Å; A244-A246 PolarHBondContact O-N 3.24Å; A244-Y247 WeakPolarHBondContact O-CA 3.39Å; A244-Y247 WeakPolarHBondContact O-CB 3.35Å; A244-Y247 PolarHBondContact O-N 3.24Å; A244-G248 PolarHBondContact O-N 3.25Å; A244-F249 CarbonylContact C-O 3.6Å; A244-F249 HydrophobicContact CB-CB 4.36Å; A244-F249 PolarHBondContact O-N 3.24Å; A244-F249 VanDerWaalsContact O-N 3.11Å; A244-I251 HydrophobicContact CB-CB 4.42Å; A244-I251 HydrophobicContact CB-CD1 3.6Å; A244-I251 HydrophobicContact CB-CG1 3.77Å; A244-I251 HydrophobicContact CB-CG2 3.76Å; A244-F267 HydrophobicContact CB-CD1 4.33Å; A244-F267 HydrophobicContact CB-CD2 3.69Å; A244-F267 HydrophobicContact CB-CE1 4.43Å; A244-F267 HydrophobicContact CB-CE2 3.78Å; A244-F267 HydrophobicContact CB-CG 3.99Å; A244-F267 HydrophobicContact CB-CZ 4.17Å
245A98.5Very high98.3Very high61 Ų6139.8 Ų39.850%0.50422%0.22SC..Hα-helixtrans-62.3-31175.600000112.7K241 E242 M243 Y247 G248 F249K241-A245 WeakPolarHBondContact O-CB 3.13Å; K241-A245 PolarHBondContact O-N 2.56Å; E242-A245 PolarHBondContact O-N 3.47Å; M243-A245 VanDerWaalsContact C-N 3.29Å; M243-A245 PolarHBondContact O-N 3.21Å; A245-Y247 PolarHBondContact O-N 2.69Å; A245-G248 PolarHBondContact O-N 2.95Å; A245-F249 WeakPolarHBondContact CA-O 3.45Å; A245-F249 PolarHBondContact N-O 2.9Å
246A97.7Very high98.2Very high50 Ų5038.2 Ų38.241%0.41321%0.214SC..Hα-helixtrans-63.2-26.1174.100000112.7A94 E242 M243 A244A94-A246 WeakPolarHBondContact CB-O 3.23Å; E242-A246 PolarHBondContact O-N 3.15Å; M243-A246 WeakPolarHBondContact O-CB 3.49Å; M243-A246 PolarHBondContact O-N 2.76Å; A244-A246 PolarHBondContact O-N 3.24Å
247Y98.2Very high98.2Very high15 Ų1540.6 Ų40.66%0.05923%0.227CC..THydrogen-bonded Turntrans-90.94173.7-75.2-87.1000113.6A94 G95 Y96 V108 G109 I110 A244 A245 F249 F267A94-Y247 VanDerWaalsContact CA-CZ 3.49Å; A94-Y247 HydrophobicContact CB-CD1 3.6Å; A94-Y247 HydrophobicContact CB-CD2 4.15Å; A94-Y247 HydrophobicContact CB-CE1 3.58Å; A94-Y247 HydrophobicContact CB-CE2 4.13Å; A94-Y247 HydrophobicContact CB-CG 3.9Å; G95-Y247 PolarHBondContact N-OH 3.14Å; G95-Y247 VanDerWaalsContact O-CE1 3.24Å; G95-Y247 WeakPolarHBondContact O-CE1 3.48Å; G95-Y247 PolarHBondContact O-OH 2.94Å; Y96-Y247 HydrophobicContact CE1-CD1 4.25Å; Y96-Y247 HydrophobicContact CE1-CE1 4.35Å; V108-Y247 HydrophobicContact CB-CD1 3.9Å; V108-Y247 HydrophobicContact CB-CE1 4.22Å; V108-Y247 HydrophobicContact CG2-CD1 3.59Å; V108-Y247 HydrophobicContact CG2-CE1 4.34Å; V108-Y247 HydrophobicContact CG2-CG 4.09Å; G109-Y247 VanDerWaalsContact CA-CZ 3.47Å; G109-Y247 WeakPolarHBondContact CA-OH 3.36Å; I110-Y247 PolarHBondContact N-OH 3.3Å; I110-Y247 VanDerWaalsContact N-OH 3.1Å; A244-Y247 WeakPolarHBondContact O-CA 3.39Å; A244-Y247 WeakPolarHBondContact O-CB 3.35Å; A244-Y247 PolarHBondContact O-N 3.24Å; A245-Y247 PolarHBondContact O-N 2.69Å; Y247-F249 WeakPolarHBondContact O-CD2 3.13Å; Y247-F267 AromaticContact CD2-CE1 3.93Å; Y247-F267 HydrophobicContact CD2-CE1 3.93Å; Y247-F267 HydrophobicContact CD2-CZ 4.34Å; Y247-F267 HydrophobicContact CG-CE1 4.16Å; Y247-F267 HydrophobicContact CG-CZ 4.18Å
248G97.9Very high98.2Very high71 Ų7140.6 Ų40.673%0.73223%0.227SC*.THydrogen-bonded Turntrans82.915.2-17900000115.1A244 A245A244-G248 PolarHBondContact O-N 3.25Å; A245-G248 PolarHBondContact O-N 2.95Å
249F98.5Very high98.2Very high43 Ų4339.9 Ų39.919%0.18922%0.224CC..  trans-105.4131.9179.7-69.9-90.4000112V108 A244 A245 Y247 I251 Q263 W264 F267V108-F249 HydrophobicContact CG2-CD2 4.3Å; V108-F249 HydrophobicContact CG2-CE2 3.53Å; V108-F249 HydrophobicContact CG2-CZ 4.29Å; A244-F249 CarbonylContact C-O 3.6Å; A244-F249 HydrophobicContact CB-CB 4.36Å; A244-F249 PolarHBondContact O-N 3.24Å; A244-F249 VanDerWaalsContact O-N 3.11Å; A245-F249 WeakPolarHBondContact CA-O 3.45Å; A245-F249 PolarHBondContact N-O 2.9Å; Y247-F249 WeakPolarHBondContact O-CD2 3.13Å; F249-I251 HydrophobicContact CB-CG2 4.21Å; F249-Q263 HydrophobicContact CD1-CG 4.16Å; F249-Q263 HydrophobicContact CE1-CG 3.86Å; F249-Q263 HydrophobicContact CE2-CG 4.33Å; F249-Q263 HydrophobicContact CG-CG 4.48Å; F249-Q263 HydrophobicContact CZ-CG 3.94Å; F249-W264 HydrophobicContact CD1-CE3 4.38Å; F249-W264 AromaticContact CD1-CH2 3.59Å; F249-W264 HydrophobicContact CD1-CH2 3.59Å; F249-W264 AromaticContact CD1-CZ3 3.34Å; F249-W264 HydrophobicContact CD1-CZ3 3.34Å; F249-W264 HydrophobicContact CE1-CH2 4.3Å; F249-W264 AromaticContact CE1-CZ3 3.8Å; F249-W264 HydrophobicContact CE1-CZ3 3.8Å; F249-W264 HydrophobicContact CG-CZ3 4.3Å; F249-F267 HydrophobicContact CB-CE2 3.74Å; F249-F267 HydrophobicContact CB-CZ 4.37Å; F249-F267 HydrophobicContact CD1-CE2 4.42Å; F249-F267 AromaticContact CD2-CE2 3.72Å; F249-F267 HydrophobicContact CD2-CE2 3.72Å; F249-F267 AromaticContact CD2-CZ 3.72Å; F249-F267 HydrophobicContact CD2-CZ 3.72Å; F249-F267 HydrophobicContact CE2-CE2 4.44Å; F249-F267 HydrophobicContact CE2-CZ 4.31Å; F249-F267 AromaticContact CG-CE2 3.7Å; F249-F267 HydrophobicContact CG-CE2 3.7Å; F249-F267 HydrophobicContact CG-CZ 4.18Å
250D98.1Very high98.2Very high97 Ų9738.3 Ų38.352%0.51922%0.22SC..  trans-98.296.4168.5-1773.3000110.2S252D250-S252 VanDerWaalsContact C-N 3.33Å; D250-S252 VanDerWaalsContact CG-OG 3.28Å; D250-S252 WeakPolarHBondContact OD1-CB 2.81Å; D250-S252 PolarHBondContact OD1-N 3.16Å; D250-S252 PolarHBondContact OD1-OG 2.73Å; D250-S252 PolarHBondContact OD2-OG 2.71Å
251I98.4Very high98.2Very high0 Ų038.3 Ų38.30%022%0.22CC..THydrogen-bonded Turntrans-93.11517969167.6000113.2V195 I200 I240 K241 A244 F249 R253 W264 F267V195-I251 HydrophobicContact CG1-CD1 4.15Å; I200-I251 HydrophobicContact CD1-CD1 4.18Å; I200-I251 HydrophobicContact CG1-CD1 3.54Å; I200-I251 HydrophobicContact CG1-CG1 3.72Å; I200-I251 PolarHBondContact N-O 3.05Å; I240-I251 HydrophobicContact CG2-CD1 3.8Å; K241-I251 HydrophobicContact CB-CG1 4.4Å; K241-I251 HydrophobicContact CG-CG1 4.42Å; A244-I251 HydrophobicContact CB-CB 4.42Å; A244-I251 HydrophobicContact CB-CD1 3.6Å; A244-I251 HydrophobicContact CB-CG1 3.77Å; A244-I251 HydrophobicContact CB-CG2 3.76Å; F249-I251 HydrophobicContact CB-CG2 4.21Å; I251-R253 PolarHBondContact O-N 3.08Å; I251-W264 HydrophobicContact CB-CD2 4.45Å; I251-W264 HydrophobicContact CB-CG 4.4Å; I251-W264 HydrophobicContact CG2-CD2 3.7Å; I251-W264 HydrophobicContact CG2-CE3 4.19Å; I251-W264 HydrophobicContact CG2-CG 4.01Å; I251-W264 HydrophobicContact CG2-CZ2 4.02Å; I251-F267 HydrophobicContact CG2-CD2 4.01Å; I251-F267 HydrophobicContact CG2-CE2 4.46Å
252S98Very high98.2Very high25 Ų2535.6 Ų35.618%0.17521%0.207CC..THydrogen-bonded Turntrans-58.6-35.2172.260.10000111.4I200 D201 D250I200-S252 PolarHBondContact N-O 2.97Å; D201-S252 WeakPolarHBondContact CB-O 3.48Å; D201-S252 PolarHBondContact N-O 2.54Å; D201-S252 VanDerWaalsContact N-O 3.09Å; D250-S252 VanDerWaalsContact C-N 3.33Å; D250-S252 VanDerWaalsContact CG-OG 3.28Å; D250-S252 WeakPolarHBondContact OD1-CB 2.81Å; D250-S252 PolarHBondContact OD1-N 3.16Å; D250-S252 PolarHBondContact OD1-OG 2.73Å; D250-S252 PolarHBondContact OD2-OG 2.71Å
253R96.7Very high98.2Very high53 Ų5331.8 Ų31.820%0.219%0.19CC..SBendtrans-96.1159.7179.464159.7178.280.3-5.1113.3T14 G199 I251 E256 E260 W264T14-R253 HydrophobicContact CG2-CB 3.82Å; T14-R253 HydrophobicContact CG2-CG 4.42Å; G199-R253 VanDerWaalsContact CA-C 3.44Å; G199-R253 WeakPolarHBondContact CA-O 3.32Å; I251-R253 PolarHBondContact O-N 3.08Å; R253-E256 IonicContact CZ-OE1 3.54Å; R253-E256 IonicContact NE-OE1 3.45Å; R253-E256 PolarHBondContact NE-OE1 2.8Å; R253-E256 IonicContact NH1-OE1 3.74Å; R253-E260 IonicContact CZ-OE1 3.62Å; R253-E260 IonicContact CZ-OE2 3.47Å; R253-E260 IonicContact NH1-OE1 3.62Å; R253-E260 IonicContact NH1-OE2 2.7Å; R253-E260 PolarHBondContact NH1-OE2 3.06Å; R253-E260 IonicContact NH2-OE1 2.72Å; R253-E260 PolarHBondContact NH2-OE1 2.91Å; R253-E260 IonicContact NH2-OE2 3.34Å; R253-E260 PolarHBondContact NH2-OE2 3.45Å; R253-W264 PolarHBondContact O-NE1 2.89Å; R253-W264 VanDerWaalsContact O-NE1 3.08Å
254P98.1Very high98.2Very high6 Ų631.7 Ų31.74%0.03919%0.189CC..PPolyproline II helixtrans-59.9156.9168.626.4-36.4000112.2A18 L197 Y198A18-P254 HydrophobicContact CB-CB 3.99Å; A18-P254 HydrophobicContact CB-CG 3.62Å; L197-P254 VanDerWaalsContact O-CB 3.29Å; L197-P254 WeakPolarHBondContact O-CB 3.41Å; Y198-P254 WeakPolarHBondContact O-CD 3.14Å
255A98.1Very high98.2Very high0 Ų031.7 Ų31.70%019%0.189CC..PPolyproline II helixtrans-68.7132.6175.300000111.2A196 E260 A261 W264 Y293A196-A255 HydrophobicContact CB-CB 4.24Å; A196-A255 WeakPolarHBondContact O-CB 3.47Å; A196-A255 PolarHBondContact O-N 3.3Å; A255-E260 HydrophobicContact CB-CB 3.72Å; A255-A261 HydrophobicContact CB-CB 4.13Å; A255-W264 HydrophobicContact CB-CD2 4.47Å; A255-W264 HydrophobicContact CB-CG 4.24Å; A255-Y293 HydrophobicContact CB-CE1 4.45Å
256E97Very high98.3Very high73 Ų7329 Ų2934%0.34117%0.166SC..  trans-97.5-16.5-175.2-73.1175.3-172.400113.2A18 R253 E260 R296A18-E256 HydrophobicContact CB-CG 3.8Å; R253-E256 IonicContact CZ-OE1 3.54Å; R253-E256 IonicContact NE-OE1 3.45Å; R253-E256 PolarHBondContact NE-OE1 2.8Å; R253-E256 IonicContact NH1-OE1 3.74Å; E256-E260 WeakPolarHBondContact CB-OE2 3.38Å; E256-E260 PolarHBondContact N-OE2 3.18Å; E256-R296 PolarHBondContact O-NH2 2.75Å
257N97.3Very high98.3Very high50 Ų5026.6 Ų26.627%0.26715%0.146SC..SBendtrans-149.6175.2-176.362.862.6000111.5K259 E260 A261 D297N257-K259 WeakPolarHBondContact OD1-CB 3.44Å; N257-K259 PolarHBondContact OD1-N 3.17Å; N257-K259 VanDerWaalsContact OD1-N 3.13Å; N257-E260 PolarHBondContact O-N 2.75Å; N257-E260 WeakPolarHBondContact OD1-CG 3.4Å; N257-E260 PolarHBondContact OD1-N 2.77Å; N257-A261 WeakPolarHBondContact O-CB 3.49Å; N257-A261 PolarHBondContact O-N 3.41Å; N257-D297 WeakPolarHBondContact CA-OD2 3.26Å; N257-D297 VanDerWaalsContact CB-OD2 3.25Å; N257-D297 WeakPolarHBondContact CB-OD2 3.33Å
258A98.6Very high98.4Very high0 Ų025.9 Ų25.90%014%0.143CC..Hα-helixtrans-60.1-45.7-178.400000113.1E260 A261 V262 I294 D297 L303 L311A258-E260 VanDerWaalsContact C-N 3.3Å; A258-E260 PolarHBondContact O-N 2.98Å; A258-A261 PolarHBondContact O-N 2.79Å; A258-V262 WeakPolarHBondContact O-CG2 3.1Å; A258-V262 PolarHBondContact O-N 2.91Å; A258-I294 HydrophobicContact CB-CG1 3.87Å; A258-D297 HydrophobicContact CB-CB 4.35Å; A258-D297 WeakPolarHBondContact CB-OD2 3.26Å; A258-D297 PolarHBondContact N-OD2 3.4Å; A258-L303 HydrophobicContact CB-CD2 3.87Å; A258-L311 HydrophobicContact CB-CD1 4.13Å
259K98.6Very high98.4Very high92 Ų9222.5 Ų22.540%0.411%0.109SC..Hα-helixtrans-58.8-44.8178.1177.1171.6177.6162.10110.8A106 N257 Q263 L311A106-K259 WeakPolarHBondContact O-CE 3.32Å; N257-K259 WeakPolarHBondContact OD1-CB 3.44Å; N257-K259 PolarHBondContact OD1-N 3.17Å; N257-K259 VanDerWaalsContact OD1-N 3.13Å; K259-Q263 WeakPolarHBondContact O-CB 3.44Å; K259-Q263 PolarHBondContact O-N 3.26Å; K259-L311 HydrophobicContact CB-CD1 4.4Å; K259-L311 HydrophobicContact CB-CD2 3.94Å; K259-L311 HydrophobicContact CG-CD2 3.97Å
260E98.7Very high98.4Very high27 Ų2720.4 Ų20.413%0.12610%0.1CC..Hα-helixtrans-67.6-40.5176.4-64.9-172.6168.400112.5R253 A255 E256 N257 A258 V262 Q263 W264R253-E260 IonicContact CZ-OE1 3.62Å; R253-E260 IonicContact CZ-OE2 3.47Å; R253-E260 IonicContact NH1-OE1 3.62Å; R253-E260 IonicContact NH1-OE2 2.7Å; R253-E260 PolarHBondContact NH1-OE2 3.06Å; R253-E260 IonicContact NH2-OE1 2.72Å; R253-E260 PolarHBondContact NH2-OE1 2.91Å; R253-E260 IonicContact NH2-OE2 3.34Å; R253-E260 PolarHBondContact NH2-OE2 3.45Å; A255-E260 HydrophobicContact CB-CB 3.72Å; E256-E260 WeakPolarHBondContact CB-OE2 3.38Å; E256-E260 PolarHBondContact N-OE2 3.18Å; N257-E260 PolarHBondContact O-N 2.75Å; N257-E260 WeakPolarHBondContact OD1-CG 3.4Å; N257-E260 PolarHBondContact OD1-N 2.77Å; A258-E260 VanDerWaalsContact C-N 3.3Å; A258-E260 PolarHBondContact O-N 2.98Å; E260-V262 VanDerWaalsContact C-N 3.32Å; E260-V262 PolarHBondContact O-N 3.05Å; E260-Q263 PolarHBondContact O-N 3.19Å; E260-W264 HydrophobicContact CB-CD2 4.12Å; E260-W264 HydrophobicContact CB-CE3 3.72Å; E260-W264 HydrophobicContact CB-CH2 3.74Å; E260-W264 HydrophobicContact CB-CZ2 4.16Å; E260-W264 HydrophobicContact CB-CZ3 3.5Å; E260-W264 VanDerWaalsContact CD-CH2 3.49Å; E260-W264 HydrophobicContact CG-CE3 4.21Å; E260-W264 HydrophobicContact CG-CH2 3.38Å; E260-W264 HydrophobicContact CG-CZ2 4.1Å; E260-W264 HydrophobicContact CG-CZ3 3.46Å; E260-W264 VanDerWaalsContact CG-CZ3 3.46Å; E260-W264 VanDerWaalsContact O-CB 3.24Å; E260-W264 WeakPolarHBondContact O-CB 3.38Å; E260-W264 VanDerWaalsContact O-CD2 3.3Å; E260-W264 PolarHBondContact O-N 3.41Å
261A98.9Very high98.4Very high0 Ų015.8 Ų15.80%08%0.075CC..Hα-helixtrans-61.8-42.5179.700000111.7A196 A255 N257 A258 T265 L290 Y293A196-A261 HydrophobicContact CB-CB 4.38Å; A196-A261 WeakPolarHBondContact CB-O 3.44Å; A255-A261 HydrophobicContact CB-CB 4.13Å; N257-A261 WeakPolarHBondContact O-CB 3.49Å; N257-A261 PolarHBondContact O-N 3.41Å; A258-A261 PolarHBondContact O-N 2.79Å; A261-T265 VanDerWaalsContact O-CB 3.31Å; A261-T265 WeakPolarHBondContact O-CB 3.24Å; A261-T265 PolarHBondContact O-N 2.87Å; A261-T265 PolarHBondContact O-OG1 3.39Å; A261-L290 HydrophobicContact CB-CD2 4.28Å; A261-Y293 HydrophobicContact CB-CD1 3.7Å; A261-Y293 HydrophobicContact CB-CD2 3.62Å; A261-Y293 HydrophobicContact CB-CE1 4.1Å; A261-Y293 HydrophobicContact CB-CE2 4.05Å; A261-Y293 HydrophobicContact CB-CG 3.43Å; A261-Y293 VanDerWaalsContact CB-CG 3.43Å
262V99Very high98.5Very high0 Ų015.8 Ų15.80%08%0.075CC..Hα-helixtrans-64.7-49.5174.3179.40000110.4I107 A258 E260 W264 T265 Y266 L290 L311 L315I107-V262 HydrophobicContact CD1-CB 3.76Å; I107-V262 HydrophobicContact CD1-CG1 3.41Å; I107-V262 VanDerWaalsContact CD1-CG1 3.41Å; I107-V262 HydrophobicContact CG1-CG1 3.75Å; A258-V262 WeakPolarHBondContact O-CG2 3.1Å; A258-V262 PolarHBondContact O-N 2.91Å; E260-V262 VanDerWaalsContact C-N 3.32Å; E260-V262 PolarHBondContact O-N 3.05Å; V262-W264 PolarHBondContact O-N 3.35Å; V262-T265 PolarHBondContact O-N 2.95Å; V262-Y266 WeakPolarHBondContact O-CB 3.34Å; V262-Y266 PolarHBondContact O-N 3.05Å; V262-L290 HydrophobicContact CB-CD2 4.47Å; V262-L290 HydrophobicContact CG2-CD1 4.28Å; V262-L290 HydrophobicContact CG2-CD2 3.99Å; V262-L311 HydrophobicContact CG2-CB 4.38Å; V262-L315 HydrophobicContact CG1-CB 3.86Å; V262-L315 HydrophobicContact CG1-CD2 4.04Å; V262-L315 HydrophobicContact CG1-CG 4.35Å
263Q98.9Very high98.5Very high0 Ų014.6 Ų14.60%07%0.067CC..Hα-helixtrans-66.1-38.6-177-179.866.872.800113.3I107 V108 F249 K259 E260 Y266 F267I107-Q263 HydrophobicContact CD1-CB 4.04Å; V108-Q263 PolarHBondContact O-NE2 2.99Å; F249-Q263 HydrophobicContact CD1-CG 4.16Å; F249-Q263 HydrophobicContact CE1-CG 3.86Å; F249-Q263 HydrophobicContact CE2-CG 4.33Å; F249-Q263 HydrophobicContact CG-CG 4.48Å; F249-Q263 HydrophobicContact CZ-CG 3.94Å; K259-Q263 WeakPolarHBondContact O-CB 3.44Å; K259-Q263 PolarHBondContact O-N 3.26Å; E260-Q263 PolarHBondContact O-N 3.19Å; Q263-Y266 PolarHBondContact O-N 3.29Å; Q263-F267 HydrophobicContact CG-CD2 3.89Å; Q263-F267 HydrophobicContact CG-CE2 3.46Å; Q263-F267 VanDerWaalsContact CG-CE2 3.46Å; Q263-F267 HydrophobicContact CG-CZ 4.09Å; Q263-F267 VanDerWaalsContact NE2-CE2 3.31Å; Q263-F267 VanDerWaalsContact O-CD2 3.3Å; Q263-F267 WeakPolarHBondContact O-CD2 3.23Å; Q263-F267 WeakPolarHBondContact O-CG 3.46Å; Q263-F267 PolarHBondContact O-N 3.32Å
264W98.9Very high98.6Very high2 Ų212.1 Ų12.11%0.0086%0.057CC..Hα-helixtrans-70.9-42.6-179.1-85.1-135.8000109.7V195 A196 F249 I251 R253 A255 E260 V262 Y266 F267 G268V195-W264 HydrophobicContact CG1-CB 4.07Å; V195-W264 HydrophobicContact CG1-CG 4.48Å; V195-W264 WeakPolarHBondContact CG1-O 3.41Å; A196-W264 HydrophobicContact CB-CB 3.85Å; F249-W264 HydrophobicContact CD1-CE3 4.38Å; F249-W264 AromaticContact CD1-CH2 3.59Å; F249-W264 HydrophobicContact CD1-CH2 3.59Å; F249-W264 AromaticContact CD1-CZ3 3.34Å; F249-W264 HydrophobicContact CD1-CZ3 3.34Å; F249-W264 HydrophobicContact CE1-CH2 4.3Å; F249-W264 AromaticContact CE1-CZ3 3.8Å; F249-W264 HydrophobicContact CE1-CZ3 3.8Å; F249-W264 HydrophobicContact CG-CZ3 4.3Å; I251-W264 HydrophobicContact CB-CD2 4.45Å; I251-W264 HydrophobicContact CB-CG 4.4Å; I251-W264 HydrophobicContact CG2-CD2 3.7Å; I251-W264 HydrophobicContact CG2-CE3 4.19Å; I251-W264 HydrophobicContact CG2-CG 4.01Å; I251-W264 HydrophobicContact CG2-CZ2 4.02Å; R253-W264 PolarHBondContact O-NE1 2.89Å; R253-W264 VanDerWaalsContact O-NE1 3.08Å; A255-W264 HydrophobicContact CB-CD2 4.47Å; A255-W264 HydrophobicContact CB-CG 4.24Å; E260-W264 HydrophobicContact CB-CD2 4.12Å; E260-W264 HydrophobicContact CB-CE3 3.72Å; E260-W264 HydrophobicContact CB-CH2 3.74Å; E260-W264 HydrophobicContact CB-CZ2 4.16Å; E260-W264 HydrophobicContact CB-CZ3 3.5Å; E260-W264 VanDerWaalsContact CD-CH2 3.49Å; E260-W264 HydrophobicContact CG-CE3 4.21Å; E260-W264 HydrophobicContact CG-CH2 3.38Å; E260-W264 HydrophobicContact CG-CZ2 4.1Å; E260-W264 HydrophobicContact CG-CZ3 3.46Å; E260-W264 VanDerWaalsContact CG-CZ3 3.46Å; E260-W264 VanDerWaalsContact O-CB 3.24Å; E260-W264 WeakPolarHBondContact O-CB 3.38Å; E260-W264 VanDerWaalsContact O-CD2 3.3Å; E260-W264 PolarHBondContact O-N 3.41Å; V262-W264 PolarHBondContact O-N 3.35Å; W264-Y266 VanDerWaalsContact C-N 3.31Å; W264-Y266 PolarHBondContact O-N 3.3Å; W264-F267 PolarHBondContact O-N 3.47Å; W264-G268 PolarHBondContact O-N 3.3Å
265T99Very high98.5Very high1 Ų112.8 Ų12.81%0.0066%0.06CC..Hα-helixtrans-58.9-46.3173.1-57.40000110Y192 A196 A261 V262 F267 G268 Y269 V286Y192-T265 WeakPolarHBondContact CB-O 3.35Å; A196-T265 WeakPolarHBondContact CB-OG1 3.2Å; A261-T265 VanDerWaalsContact O-CB 3.31Å; A261-T265 WeakPolarHBondContact O-CB 3.24Å; A261-T265 PolarHBondContact O-N 2.87Å; A261-T265 PolarHBondContact O-OG1 3.39Å; V262-T265 PolarHBondContact O-N 2.95Å; T265-F267 PolarHBondContact O-N 2.63Å; T265-G268 PolarHBondContact O-N 3.06Å; T265-Y269 PolarHBondContact O-N 3.42Å; T265-V286 HydrophobicContact CG2-CB 4.42Å; T265-V286 HydrophobicContact CG2-CG1 3.88Å
266Y98.9Very high98.5Very high3 Ų313.1 Ų13.11%0.0126%0.061CC..Hα-helixtrans-63.8-38.5176.8-177.7-119.9000112.8I107 V108 G109 V262 Q263 W264 G268 Y269 L270 L315 K318 L319I107-Y266 HydrophobicContact CG2-CD1 3.96Å; I107-Y266 HydrophobicContact CG2-CG 4.34Å; V108-Y266 WeakPolarHBondContact O-CD1 3.4Å; V108-Y266 WeakPolarHBondContact O-CE1 3.48Å; G109-Y266 WeakPolarHBondContact O-CE1 3.46Å; G109-Y266 PolarHBondContact O-OH 3.5Å; V262-Y266 WeakPolarHBondContact O-CB 3.34Å; V262-Y266 PolarHBondContact O-N 3.05Å; Q263-Y266 PolarHBondContact O-N 3.29Å; W264-Y266 VanDerWaalsContact C-N 3.31Å; W264-Y266 PolarHBondContact O-N 3.3Å; Y266-G268 VanDerWaalsContact C-N 3.31Å; Y266-G268 PolarHBondContact O-N 3.26Å; Y266-Y269 HydrophobicContact CD2-CD1 4.18Å; Y266-Y269 HydrophobicContact CE2-CD1 4.04Å; Y266-Y269 CarbonylContact O-C 3.49Å; Y266-Y269 PolarHBondContact O-N 2.76Å; Y266-Y269 VanDerWaalsContact O-N 3.16Å; Y266-L270 HydrophobicContact CE1-CB 4.43Å; Y266-L270 HydrophobicContact CE1-CD2 4.45Å; Y266-L270 VanDerWaalsContact O-CB 3.3Å; Y266-L270 WeakPolarHBondContact O-CB 3.47Å; Y266-L270 PolarHBondContact O-N 3.13Å; Y266-L315 HydrophobicContact CD2-CD1 3.84Å; Y266-L315 HydrophobicContact CG-CD1 4.04Å; Y266-K318 HydrophobicContact CE1-CB 3.97Å; Y266-K318 HydrophobicContact CE1-CG 3.92Å; Y266-K318 HydrophobicContact CE2-CB 3.78Å; Y266-K318 VanDerWaalsContact CZ-CB 3.48Å; Y266-K318 WeakPolarHBondContact OH-CB 3.36Å; Y266-L319 HydrophobicContact CD2-CD2 4.4Å; Y266-L319 HydrophobicContact CE2-CD2 4.24Å
267F98.9Very high98.5Very high0 Ų010.5 Ų10.50%05%0.05CC..Hα-helixtrans-64-34.4175-77.1-44.6000113.1V108 M243 A244 Y247 F249 I251 Q263 W264 T265 L270 A271V108-F267 HydrophobicContact CG2-CZ 4.24Å; M243-F267 HydrophobicContact CE-CB 4.18Å; M243-F267 HydrophobicContact CE-CD1 4.03Å; M243-F267 HydrophobicContact CE-CG 4.5Å; M243-F267 WeakPolarHBondContact CE-O 3.1Å; A244-F267 HydrophobicContact CB-CD1 4.33Å; A244-F267 HydrophobicContact CB-CD2 3.69Å; A244-F267 HydrophobicContact CB-CE1 4.43Å; A244-F267 HydrophobicContact CB-CE2 3.78Å; A244-F267 HydrophobicContact CB-CG 3.99Å; A244-F267 HydrophobicContact CB-CZ 4.17Å; Y247-F267 AromaticContact CD2-CE1 3.93Å; Y247-F267 HydrophobicContact CD2-CE1 3.93Å; Y247-F267 HydrophobicContact CD2-CZ 4.34Å; Y247-F267 HydrophobicContact CG-CE1 4.16Å; Y247-F267 HydrophobicContact CG-CZ 4.18Å; F249-F267 HydrophobicContact CB-CE2 3.74Å; F249-F267 HydrophobicContact CB-CZ 4.37Å; F249-F267 HydrophobicContact CD1-CE2 4.42Å; F249-F267 AromaticContact CD2-CE2 3.72Å; F249-F267 HydrophobicContact CD2-CE2 3.72Å; F249-F267 AromaticContact CD2-CZ 3.72Å; F249-F267 HydrophobicContact CD2-CZ 3.72Å; F249-F267 HydrophobicContact CE2-CE2 4.44Å; F249-F267 HydrophobicContact CE2-CZ 4.31Å; F249-F267 AromaticContact CG-CE2 3.7Å; F249-F267 HydrophobicContact CG-CE2 3.7Å; F249-F267 HydrophobicContact CG-CZ 4.18Å; I251-F267 HydrophobicContact CG2-CD2 4.01Å; I251-F267 HydrophobicContact CG2-CE2 4.46Å; Q263-F267 HydrophobicContact CG-CD2 3.89Å; Q263-F267 HydrophobicContact CG-CE2 3.46Å; Q263-F267 VanDerWaalsContact CG-CE2 3.46Å; Q263-F267 HydrophobicContact CG-CZ 4.09Å; Q263-F267 VanDerWaalsContact NE2-CE2 3.31Å; Q263-F267 VanDerWaalsContact O-CD2 3.3Å; Q263-F267 WeakPolarHBondContact O-CD2 3.23Å; Q263-F267 WeakPolarHBondContact O-CG 3.46Å; Q263-F267 PolarHBondContact O-N 3.32Å; W264-F267 PolarHBondContact O-N 3.47Å; T265-F267 PolarHBondContact O-N 2.63Å; F267-L270 HydrophobicContact CD1-CD2 4.03Å; F267-L270 HydrophobicContact CE1-CD2 4.33Å; F267-L270 PolarHBondContact O-N 3.44Å; F267-A271 PolarHBondContact O-N 3.08Å; F267-A271 VanDerWaalsContact O-N 3.14Å
268G98.8Very high98.5Very high0 Ų08.2 Ų8.20%04%0.038CC..Hα-helixtrans-58-49.4170.100000111.7W264 T265 Y266 A271 A272W264-G268 PolarHBondContact O-N 3.3Å; T265-G268 PolarHBondContact O-N 3.06Å; Y266-G268 VanDerWaalsContact C-N 3.31Å; Y266-G268 PolarHBondContact O-N 3.26Å; G268-A271 PolarHBondContact O-N 2.96Å; G268-A272 PolarHBondContact O-N 3.34Å
269Y98.9Very high98.3Very high0 Ų08.3 Ų8.30%04%0.038CC..Hα-helixtrans-67.8-39178.5179.1-109.2000112.9Y192 T265 Y266 A271 A272 I273 M281 I283 L319 V322Y192-Y269 HydrophobicContact CD2-CD2 4.23Å; Y192-Y269 HydrophobicContact CE1-CD2 4.38Å; Y192-Y269 AromaticContact CE2-CD2 3.69Å; Y192-Y269 HydrophobicContact CE2-CD2 3.69Å; Y192-Y269 HydrophobicContact CE2-CG 4.49Å; Y192-Y269 AromaticContact CZ-CD2 3.77Å; T265-Y269 PolarHBondContact O-N 3.42Å; Y266-Y269 HydrophobicContact CD2-CD1 4.18Å; Y266-Y269 HydrophobicContact CE2-CD1 4.04Å; Y266-Y269 CarbonylContact O-C 3.49Å; Y266-Y269 PolarHBondContact O-N 2.76Å; Y266-Y269 VanDerWaalsContact O-N 3.16Å; Y269-A271 VanDerWaalsContact C-N 3.27Å; Y269-A271 PolarHBondContact O-N 3.49Å; Y269-A272 VanDerWaalsContact O-CB 3.31Å; Y269-A272 WeakPolarHBondContact O-CB 3.33Å; Y269-A272 PolarHBondContact O-N 3.15Å; Y269-I273 HydrophobicContact CD1-CD1 4.32Å; Y269-I273 HydrophobicContact CD2-CG2 4.47Å; Y269-I273 HydrophobicContact CE1-CD1 3.94Å; Y269-I273 HydrophobicContact CE1-CG2 3.94Å; Y269-I273 HydrophobicContact CE2-CG2 3.84Å; Y269-I273 PolarHBondContact O-N 2.78Å; Y269-I273 VanDerWaalsContact O-N 3.08Å; Y269-M281 VanDerWaalsContact CE2-O 3.31Å; Y269-M281 WeakPolarHBondContact CE2-O 3.28Å; Y269-M281 PolarHBondContact OH-O 3.03Å; Y269-I283 HydrophobicContact CD2-CB 4.19Å; Y269-I283 HydrophobicContact CD2-CG1 4.2Å; Y269-I283 HydrophobicContact CE2-CB 4.23Å; Y269-I283 HydrophobicContact CG-CD1 4.44Å; Y269-I283 HydrophobicContact CG-CG1 4.17Å; Y269-L319 HydrophobicContact CD1-CD2 3.71Å; Y269-L319 HydrophobicContact CE1-CD2 3.43Å; Y269-L319 VanDerWaalsContact CE1-CD2 3.43Å; Y269-V322 HydrophobicContact CE1-CG2 4.18Å
270L98.9Very high98.2Very high0 Ų04 Ų40%02%0.02CC..Hα-helixtrans-60.2-38.7178.8-17867.2000111.3M243 Y266 F267 A272 I273 K274M243-L270 HydrophobicContact CE-CB 4.06Å; M243-L270 HydrophobicContact CE-CD2 4.03Å; M243-L270 HydrophobicContact CE-CG 4.16Å; M243-L270 HydrophobicContact SD-CB 4.39Å; M243-L270 HydrophobicContact SD-CD2 3.79Å; M243-L270 HydrophobicContact SD-CG 3.87Å; Y266-L270 HydrophobicContact CE1-CB 4.43Å; Y266-L270 HydrophobicContact CE1-CD2 4.45Å; Y266-L270 VanDerWaalsContact O-CB 3.3Å; Y266-L270 WeakPolarHBondContact O-CB 3.47Å; Y266-L270 PolarHBondContact O-N 3.13Å; F267-L270 HydrophobicContact CD1-CD2 4.03Å; F267-L270 HydrophobicContact CE1-CD2 4.33Å; F267-L270 PolarHBondContact O-N 3.44Å; L270-A272 VanDerWaalsContact C-N 3.35Å; L270-I273 HydrophobicContact CD1-CD1 4.15Å; L270-I273 HydrophobicContact CD1-CG1 4.3Å; L270-I273 WeakPolarHBondContact O-CG1 3.31Å; L270-K274 HydrophobicContact CD1-CD 4.44Å; L270-K274 HydrophobicContact CD1-CG 4.44Å; L270-K274 HydrophobicContact CG-CD 4.11Å; L270-K274 HydrophobicContact CG-CG 4.49Å; L270-K274 WeakPolarHBondContact O-CB 3.3Å; L270-K274 VanDerWaalsContact O-CG 3.27Å; L270-K274 WeakPolarHBondContact O-CG 3.46Å; L270-K274 PolarHBondContact O-N 3.49Å
271A98.8Very high98.2Very high0 Ų02.7 Ų2.70%01%0.014CC..Hα-helixtrans-63.3-41.5174.800000111.8A89 I240 M243 F267 G268 Y269 K274 E275 A516A89-A271 HydrophobicContact CB-CB 3.93Å; I240-A271 HydrophobicContact CB-CB 4.37Å; I240-A271 HydrophobicContact CD1-CB 3.79Å; I240-A271 HydrophobicContact CG1-CB 3.59Å; I240-A271 HydrophobicContact CG2-CB 4.22Å; M243-A271 HydrophobicContact CE-CB 3.95Å; M243-A271 HydrophobicContact SD-CB 4.46Å; F267-A271 PolarHBondContact O-N 3.08Å; F267-A271 VanDerWaalsContact O-N 3.14Å; G268-A271 PolarHBondContact O-N 2.96Å; Y269-A271 VanDerWaalsContact C-N 3.27Å; Y269-A271 PolarHBondContact O-N 3.49Å; A271-K274 PolarHBondContact O-N 2.78Å; A271-E275 WeakPolarHBondContact O-CG 3.33Å; A271-E275 PolarHBondContact O-N 3.11Å; A271-E275 VanDerWaalsContact O-N 3.07Å; A271-A516 HydrophobicContact CB-CB 4.32Å
272A98.6Very high98.2Very high0 Ų02.7 Ų2.70%01%0.014CC..Hα-helixtrans-58.9-53.9176.200000111.3Y192 G268 Y269 L270 K274 E275 Q276 M281 E517Y192-A272 HydrophobicContact CE1-CB 4.05Å; G268-A272 PolarHBondContact O-N 3.34Å; Y269-A272 VanDerWaalsContact O-CB 3.31Å; Y269-A272 WeakPolarHBondContact O-CB 3.33Å; Y269-A272 PolarHBondContact O-N 3.15Å; L270-A272 VanDerWaalsContact C-N 3.35Å; A272-K274 PolarHBondContact O-N 3.45Å; A272-E275 PolarHBondContact O-N 3.33Å; A272-E275 VanDerWaalsContact O-N 3.12Å; A272-Q276 PolarHBondContact O-N 3.49Å; A272-M281 HydrophobicContact CB-CE 4Å; A272-E517 HydrophobicContact CB-CG 3.39Å
273I98.5Very high98.2Very high0 Ų02.8 Ų2.80%02%0.015CC..Hα-helixtrans-73.2-7.3-179.163.9170.4000114.3Q111 M121 Y269 L270 M281 V322 F324Q111-I273 HydrophobicContact CG-CB 4.33Å; Q111-I273 HydrophobicContact CG-CD1 3.61Å; Q111-I273 HydrophobicContact CG-CG1 3.8Å; Q111-I273 PolarHBondContact NE2-O 3.36Å; M121-I273 VanDerWaalsContact CE-O 3.31Å; M121-I273 WeakPolarHBondContact CE-O 3.39Å; Y269-I273 HydrophobicContact CD1-CD1 4.32Å; Y269-I273 HydrophobicContact CD2-CG2 4.47Å; Y269-I273 HydrophobicContact CE1-CD1 3.94Å; Y269-I273 HydrophobicContact CE1-CG2 3.94Å; Y269-I273 HydrophobicContact CE2-CG2 3.84Å; Y269-I273 PolarHBondContact O-N 2.78Å; Y269-I273 VanDerWaalsContact O-N 3.08Å; L270-I273 HydrophobicContact CD1-CD1 4.15Å; L270-I273 HydrophobicContact CD1-CG1 4.3Å; L270-I273 WeakPolarHBondContact O-CG1 3.31Å; I273-M281 HydrophobicContact CG2-CB 3.9Å; I273-M281 HydrophobicContact CG2-CE 4.19Å; I273-M281 HydrophobicContact CG2-CG 4.26Å; I273-V322 HydrophobicContact CB-CG1 4.26Å; I273-V322 HydrophobicContact CD1-CB 4.31Å; I273-V322 HydrophobicContact CD1-CG1 3.91Å; I273-V322 HydrophobicContact CD1-CG2 3.49Å; I273-V322 VanDerWaalsContact CD1-CG2 3.49Å; I273-V322 HydrophobicContact CG2-CG1 4.15Å; I273-F324 HydrophobicContact CB-CZ 4.04Å; I273-F324 HydrophobicContact CG2-CZ 4.21Å
274K98.5Very high98.2Very high1 Ų12.9 Ų2.90%0.0042%0.015CC..Hα-helixtrans-91.1-25.6169.3-81.1180-177.2-85.50112.8S87 A89 I110 Q111 M243 L270 A271 A272S87-K274 VanDerWaalsContact CB-O 3.28Å; S87-K274 WeakPolarHBondContact CB-O 3.47Å; S87-K274 PolarHBondContact OG-O 2.82Å; A89-K274 WeakPolarHBondContact O-CD 3.48Å; I110-K274 WeakPolarHBondContact O-CE 3.23Å; I110-K274 PolarHBondContact O-NZ 2.79Å; Q111-K274 WeakPolarHBondContact O-CG 3.5Å; Q111-K274 PolarHBondContact O-NZ 2.97Å; M243-K274 HydrophobicContact SD-CD 3.54Å; M243-K274 VanDerWaalsContact SD-CD 3.54Å; L270-K274 HydrophobicContact CD1-CD 4.44Å; L270-K274 HydrophobicContact CD1-CG 4.44Å; L270-K274 HydrophobicContact CG-CD 4.11Å; L270-K274 HydrophobicContact CG-CG 4.49Å; L270-K274 WeakPolarHBondContact O-CB 3.3Å; L270-K274 VanDerWaalsContact O-CG 3.27Å; L270-K274 WeakPolarHBondContact O-CG 3.46Å; L270-K274 PolarHBondContact O-N 3.49Å; A271-K274 PolarHBondContact O-N 2.78Å; A272-K274 PolarHBondContact O-N 3.45Å
275E97.1Very high98.2Very high19 Ų193 Ų39%0.0892%0.016CC..Hα-helixtrans-100.5-25.8-178.3-67.7-166.3177.500113.1A89 R239 A271 A272 Y512A89-E275 HydrophobicContact CB-CG 4.13Å; A89-E275 VanDerWaalsContact CB-OE1 3.3Å; A89-E275 WeakPolarHBondContact CB-OE1 3.43Å; A89-E275 PolarHBondContact N-OE1 3.41Å; R239-E275 IonicContact CZ-OE1 3.34Å; R239-E275 IonicContact CZ-OE2 3.86Å; R239-E275 IonicContact NE-OE1 2.74Å; R239-E275 PolarHBondContact NE-OE1 3.42Å; R239-E275 IonicContact NE-OE2 4Å; R239-E275 IonicContact NH2-OE1 3.1Å; R239-E275 PolarHBondContact NH2-OE1 3.43Å; R239-E275 VanDerWaalsContact NH2-OE1 3.1Å; R239-E275 IonicContact NH2-OE2 2.88Å; R239-E275 PolarHBondContact NH2-OE2 3.36Å; A271-E275 WeakPolarHBondContact O-CG 3.33Å; A271-E275 PolarHBondContact O-N 3.11Å; A271-E275 VanDerWaalsContact O-N 3.07Å; A272-E275 PolarHBondContact O-N 3.33Å; A272-E275 VanDerWaalsContact O-N 3.12Å; E275-Y512 PolarHBondContact O-OH 3.24Å
276Q97.8Very high98.2Very high8 Ų83.1 Ų3.14%0.0372%0.016CC..  trans-128.3142.8-172.7-59-58.7-34.100111.6A272 M281 F324 Y512 Y513 E514A272-Q276 PolarHBondContact O-N 3.49Å; Q276-M281 HydrophobicContact CB-CE 3.9Å; Q276-M281 HydrophobicContact CB-SD 4.32Å; Q276-F324 WeakPolarHBondContact O-CE1 3.4Å; Q276-F324 WeakPolarHBondContact O-CZ 3.32Å; Q276-Y512 VanDerWaalsContact OE1-CZ 3.23Å; Q276-Y513 PolarHBondContact NE2-O 3.28Å; Q276-E514 HydrophobicContact CG-CB 4.02Å; Q276-E514 HydrophobicContact CG-CG 3.81Å
277N97Very high98.2Very high18 Ų183 Ų310%0.0962%0.015CC..  trans-115.845.517161.8-9.3000111.1M121 G184 F324 R326 Y512M121-N277 HydrophobicContact SD-CB 3.56Å; M121-N277 VanDerWaalsContact SD-CB 3.56Å; G184-N277 PolarHBondContact N-OD1 3.29Å; N277-F324 HydrophobicContact CB-CD1 3.59Å; N277-F324 HydrophobicContact CB-CE1 3.99Å; N277-F324 HydrophobicContact CB-CG 4.13Å; N277-R326 PolarHBondContact O-NH1 3.13Å; N277-Y512 PolarHBondContact N-OH 3.11Å; N277-Y512 VanDerWaalsContact OD1-CE1 3.29Å; N277-Y512 WeakPolarHBondContact OD1-CE1 3.33Å; N277-Y512 PolarHBondContact OD1-OH 3.23Å
278G97.4Very high98.2Very high1 Ų13.1 Ų3.11%0.012%0.017CC..BIsolated β-bridgetrans-45149.5171.200000111.5G184 A280 M281 R326G184-G278 CarbonylContact O-C 3.54Å; G184-G278 VanDerWaalsContact O-CA 3.27Å; G184-G278 WeakPolarHBondContact O-CA 3.44Å; G278-A280 VanDerWaalsContact C-N 3.32Å; G278-M281 VanDerWaalsContact CA-SD 3.58Å; G278-M281 PolarHBondContact N-SD 3.1Å; G278-M281 VanDerWaalsContact N-SD 3.45Å; G278-R326 PolarHBondContact O-NH2 2.95Å
279A94.3Very high98.2Very high2 Ų23.1 Ų3.12%0.0172%0.017CC..SBendtrans-53.8-56.8171.800000109.2Y183 G184 Y330 W340 F438Y183-A279 HydrophobicContact CD2-CB 4.02Å; Y183-A279 HydrophobicContact CE2-CB 3.76Å; G184-A279 PolarHBondContact O-N 3.28Å; A279-Y330 WeakPolarHBondContact CA-OH 3.46Å; A279-W340 WeakPolarHBondContact O-CZ3 3.48Å; A279-F438 HydrophobicContact CB-CE1 4.08Å
280A97.4Very high98.2Very high2 Ų23.1 Ų3.12%0.0172%0.017CC..  trans-106.4129.8171.700000111.8G186 G278 V339 W340 C424G186-A280 WeakPolarHBondContact CA-O 3.27Å; G278-A280 VanDerWaalsContact C-N 3.32Å; A280-V339 WeakPolarHBondContact CA-O 3.39Å; A280-W340 HydrophobicContact CB-CB 3.68Å; A280-W340 HydrophobicContact CB-CD2 4.16Å; A280-W340 HydrophobicContact CB-CE3 4.07Å; A280-W340 HydrophobicContact CB-CG 4.05Å; A280-C424 HydrophobicContact CB-CB 3.41Å; A280-C424 VanDerWaalsContact CB-CB 3.41Å
281M98.3Very high98.2Very high0 Ų03.2 Ų3.20%02%0.017CC..  trans-120.777.5175.7-62-58.6-61.600109.1Y269 A272 I273 Q276 G278 F324 V339 W340 A341Y269-M281 VanDerWaalsContact CE2-O 3.31Å; Y269-M281 WeakPolarHBondContact CE2-O 3.28Å; Y269-M281 PolarHBondContact OH-O 3.03Å; A272-M281 HydrophobicContact CB-CE 4Å; I273-M281 HydrophobicContact CG2-CB 3.9Å; I273-M281 HydrophobicContact CG2-CE 4.19Å; I273-M281 HydrophobicContact CG2-CG 4.26Å; Q276-M281 HydrophobicContact CB-CE 3.9Å; Q276-M281 HydrophobicContact CB-SD 4.32Å; G278-M281 VanDerWaalsContact CA-SD 3.58Å; G278-M281 PolarHBondContact N-SD 3.1Å; G278-M281 VanDerWaalsContact N-SD 3.45Å; M281-F324 HydrophobicContact CB-CE2 4.48Å; M281-F324 HydrophobicContact CG-CE2 3.74Å; M281-F324 HydrophobicContact CG-CZ 3.75Å; M281-V339 HydrophobicContact CB-CG1 4.41Å; M281-V339 PolarHBondContact N-O 3.34Å; M281-W340 CarbonylContact C-O 3.52Å; M281-W340 VanDerWaalsContact C-O 3.32Å; M281-A341 WeakPolarHBondContact O-CA 3.47Å
282S98.7Very high98.2Very high0 Ų03.5 Ų3.50%02%0.018CC..  trans-81.1143.4-173.2-54.10000112.3Y192 W340 T342 C424Y192-S282 WeakPolarHBondContact CE2-O 3.47Å; Y192-S282 PolarHBondContact OH-O 3.24Å; S282-W340 WeakPolarHBondContact CA-O 3.49Å; S282-W340 PolarHBondContact N-O 3.36Å; S282-W340 PolarHBondContact OG-O 2.99Å; S282-T342 WeakPolarHBondContact OG-CB 3.31Å; S282-T342 PolarHBondContact OG-OG1 3.24Å; S282-C424 PolarHBondContact OG-N 2.99Å
283I98.6Very high98.2Very high2 Ų23.5 Ų3.51%0.012%0.018CC..  trans-83.1-23.3177.8-166.4173.2000112.2Y192 Y269 V286 L319 T342 L343Y192-I283 HydrophobicContact CD2-CG1 4.16Å; Y192-I283 VanDerWaalsContact CD2-O 3.26Å; Y192-I283 WeakPolarHBondContact CD2-O 3.42Å; Y192-I283 WeakPolarHBondContact CE2-O 3.38Å; Y269-I283 HydrophobicContact CD2-CB 4.19Å; Y269-I283 HydrophobicContact CD2-CG1 4.2Å; Y269-I283 HydrophobicContact CE2-CB 4.23Å; Y269-I283 HydrophobicContact CG-CD1 4.44Å; Y269-I283 HydrophobicContact CG-CG1 4.17Å; I283-V286 HydrophobicContact CD1-CG2 4.31Å; I283-V286 HydrophobicContact CG1-CG1 4.18Å; I283-L319 HydrophobicContact CD1-CD1 3.9Å; I283-L319 HydrophobicContact CD1-CD2 3.88Å; I283-L319 HydrophobicContact CG2-CD1 4.36Å; I283-T342 WeakPolarHBondContact CG2-O 3.48Å; I283-T342 PolarHBondContact N-O 3.31Å; I283-T342 VanDerWaalsContact N-O 3.16Å; I283-L343 HydrophobicContact CG2-CB 3.67Å; I283-L343 HydrophobicContact CG2-CD1 3.92Å; I283-L343 HydrophobicContact CG2-CG 3.8Å
284G98.5Very high98.2Very high1 Ų13.5 Ų3.51%0.012%0.018CC..BIsolated β-bridgetrans88.6-150.6175.100000113.9V286 T342 L343 S344G284-V286 PolarHBondContact O-N 3.04Å; G284-T342 PolarHBondContact N-O 3.5Å; G284-L343 WeakPolarHBondContact O-CA 3.49Å; G284-S344 PolarHBondContact O-N 3.03Å; G284-S344 VanDerWaalsContact O-N 3.09Å
285R98.7Very high98.2Very high6 Ų64.6 Ų4.62%0.0232%0.024CC..SBendtrans-101.478-172.9-169167.1-175.3173.31112R193 A346 D418 Y420 A421R193-R285 WeakPolarHBondContact CD-O 3.42Å; R193-R285 PolarHBondContact NH1-O 2.97Å; R285-A346 PolarHBondContact NH2-O 2.82Å; R285-D418 PolarHBondContact NH1-O 2.96Å; R285-D418 VanDerWaalsContact NH1-O 3.08Å; R285-Y420 WeakPolarHBondContact CD-O 3.44Å; R285-Y420 PolarHBondContact NH1-O 3.08Å; R285-A421 HydrophobicContact CB-CB 4.09Å
286V98.9Very high98.2Very high2 Ų24.9 Ų4.91%0.0122%0.024CC..  trans-100-19.5-173.7-58.90000114.5R193 T265 I283 G284 F289 L290 L343 F363R193-V286 HydrophobicContact CG-CG1 3.97Å; T265-V286 HydrophobicContact CG2-CB 4.42Å; T265-V286 HydrophobicContact CG2-CG1 3.88Å; I283-V286 HydrophobicContact CD1-CG2 4.31Å; I283-V286 HydrophobicContact CG1-CG1 4.18Å; G284-V286 PolarHBondContact O-N 3.04Å; V286-F289 PolarHBondContact O-N 3.16Å; V286-L290 HydrophobicContact CB-CD1 4.17Å; V286-L290 HydrophobicContact CB-CG 4.48Å; V286-L290 HydrophobicContact CG2-CD1 4.17Å; V286-L290 VanDerWaalsContact O-CG 3.29Å; V286-L290 WeakPolarHBondContact O-CG 3.31Å; V286-L290 PolarHBondContact O-N 3.08Å; V286-L343 HydrophobicContact CG2-CD1 3.82Å; V286-L343 HydrophobicContact CG2-CD2 4.46Å; V286-L343 HydrophobicContact CG2-CG 4.01Å; V286-F363 HydrophobicContact CG2-CZ 4.34Å
287S98.9Very high98.3Very high0 Ų04.8 Ų4.80%02%0.023CC..Hα-helixtrans-56.7-64.6-170.6172.40000113.9F289 L290 D291 N359 D360S287-F289 PolarHBondContact O-N 3.35Å; S287-L290 PolarHBondContact O-N 3.32Å; S287-L290 VanDerWaalsContact O-N 3.16Å; S287-D291 PolarHBondContact O-N 3.4Å; S287-N359 PolarHBondContact O-ND2 3.04Å; S287-D360 VanDerWaalsContact CB-OD1 3.24Å; S287-D360 WeakPolarHBondContact CB-OD1 3.45Å; S287-D360 WeakPolarHBondContact OG-CA 3.4Å; S287-D360 VanDerWaalsContact OG-CG 3.23Å; S287-D360 PolarHBondContact OG-N 3.35Å; S287-D360 PolarHBondContact OG-OD1 2.66Å
288T98.9Very high98.3Very high4 Ų45.8 Ų5.83%0.0253%0.028CC..Hα-helixtrans-57.8-34178.1-49.90000112.7I37 Y41 L355 T357I37-T288 HydrophobicContact CG2-CG2 3.99Å; Y41-T288 HydrophobicContact CD2-CG2 3.86Å; Y41-T288 HydrophobicContact CG-CG2 4Å; T288-L355 HydrophobicContact CG2-CD2 4.06Å; T288-L355 PolarHBondContact OG1-O 3.28Å; T288-T357 HydrophobicContact CG2-CG2 3.71Å
289F98.9Very high98.3Very high0 Ų011.3 Ų11.30%06%0.058CC..Hα-helixtrans-65.8-47.5176.8166.3-97.2000111.8V33 F36 I37 R193 A196 L197 V286 S287 D291 I292 Y293V33-F289 HydrophobicContact CG1-CD2 3.95Å; V33-F289 HydrophobicContact CG1-CE2 4.22Å; F36-F289 AromaticContact CD1-CD2 3.76Å; F36-F289 HydrophobicContact CD1-CD2 3.76Å; F36-F289 AromaticContact CD1-CE2 3.66Å; F36-F289 HydrophobicContact CD1-CE2 3.66Å; F36-F289 AromaticContact CE1-CD2 3.67Å; F36-F289 HydrophobicContact CE1-CD2 3.67Å; F36-F289 AromaticContact CE1-CE2 3.45Å; F36-F289 HydrophobicContact CE1-CE2 3.45Å; F36-F289 VanDerWaalsContact CE1-CE2 3.45Å; F36-F289 HydrophobicContact CE1-CZ 4.49Å; I37-F289 HydrophobicContact CD1-CB 4.12Å; I37-F289 HydrophobicContact CG1-CB 4.21Å; I37-F289 HydrophobicContact CG1-CD2 4.26Å; R193-F289 HydrophobicContact CB-CD1 3.74Å; R193-F289 HydrophobicContact CB-CD2 4.09Å; R193-F289 HydrophobicContact CB-CE1 3.67Å; R193-F289 HydrophobicContact CB-CE2 4.02Å; R193-F289 HydrophobicContact CB-CG 3.96Å; R193-F289 HydrophobicContact CB-CZ 3.82Å; R193-F289 HydrophobicContact CG-CB 4.25Å; R193-F289 HydrophobicContact CG-CD1 3.57Å; R193-F289 HydrophobicContact CG-CD2 4.39Å; R193-F289 HydrophobicContact CG-CE1 3.99Å; R193-F289 HydrophobicContact CG-CG 3.8Å; R193-F289 WeakPolarHBondContact O-CZ 3.24Å; A196-F289 HydrophobicContact CB-CE1 3.91Å; A196-F289 HydrophobicContact CB-CZ 3.87Å; L197-F289 HydrophobicContact CB-CE2 4.18Å; L197-F289 HydrophobicContact CB-CZ 4.23Å; V286-F289 PolarHBondContact O-N 3.16Å; S287-F289 PolarHBondContact O-N 3.35Å; F289-D291 VanDerWaalsContact C-N 3.27Å; F289-D291 PolarHBondContact O-N 3.36Å; F289-I292 WeakPolarHBondContact O-CB 3.45Å; F289-I292 PolarHBondContact O-N 2.77Å; F289-Y293 HydrophobicContact CE1-CE2 4.33Å; F289-Y293 HydrophobicContact CE2-CE2 4.03Å; F289-Y293 AromaticContact CZ-CE2 3.76Å; F289-Y293 HydrophobicContact CZ-CE2 3.76Å
290L98.9Very high98.4Very high0 Ų016.2 Ų16.20%08%0.079CC..Hα-helixtrans-67-31.5179.3-67.2173.7000111.5A261 V262 V286 S287 I292 Y293 I294 L315 F363A261-L290 HydrophobicContact CB-CD2 4.28Å; V262-L290 HydrophobicContact CB-CD2 4.47Å; V262-L290 HydrophobicContact CG2-CD1 4.28Å; V262-L290 HydrophobicContact CG2-CD2 3.99Å; V286-L290 HydrophobicContact CB-CD1 4.17Å; V286-L290 HydrophobicContact CB-CG 4.48Å; V286-L290 HydrophobicContact CG2-CD1 4.17Å; V286-L290 VanDerWaalsContact O-CG 3.29Å; V286-L290 WeakPolarHBondContact O-CG 3.31Å; V286-L290 PolarHBondContact O-N 3.08Å; S287-L290 PolarHBondContact O-N 3.32Å; S287-L290 VanDerWaalsContact O-N 3.16Å; L290-I292 PolarHBondContact O-N 3.42Å; L290-Y293 PolarHBondContact O-N 2.92Å; L290-I294 PolarHBondContact O-N 2.67Å; L290-I294 VanDerWaalsContact O-N 3.12Å; L290-L315 HydrophobicContact CD1-CD2 4Å; L290-F363 HydrophobicContact CD1-CZ 4.26Å
291D98.9Very high98.4Very high1 Ų119.3 Ų19.31%0.00511%0.11CC..Hα-helixtrans-58.7-32.9176.2-161.165.1000112.5S287 F289 Y293 I294 Q295 T357 N359 R362S287-D291 PolarHBondContact O-N 3.4Å; F289-D291 VanDerWaalsContact C-N 3.27Å; F289-D291 PolarHBondContact O-N 3.36Å; D291-Y293 VanDerWaalsContact C-N 3.26Å; D291-Y293 PolarHBondContact O-N 3.45Å; D291-I294 PolarHBondContact O-N 2.99Å; D291-Q295 WeakPolarHBondContact O-CB 3.47Å; D291-Q295 PolarHBondContact O-N 3.02Å; D291-T357 HydrophobicContact CB-CG2 4.07Å; D291-T357 WeakPolarHBondContact OD2-CB 3.32Å; D291-N359 HydrophobicContact CB-CB 3.64Å; D291-N359 WeakPolarHBondContact OD1-CB 3.37Å; D291-N359 PolarHBondContact OD1-N 3.49Å; D291-R362 IonicContact OD1-NH1 2.62Å; D291-R362 PolarHBondContact OD1-NH1 2.75Å
292I98.9Very high98.3Very high6 Ų625 Ų253%0.03114%0.14CC..Hα-helixtrans-57.5-42.4179-66.1161.3000111.2F22 F36 I37 N40 F289 L290 R296F22-I292 HydrophobicContact CD1-CG2 3.97Å; F22-I292 HydrophobicContact CE1-CG2 3.42Å; F22-I292 VanDerWaalsContact CE1-CG2 3.42Å; F22-I292 HydrophobicContact CZ-CG2 3.99Å; F36-I292 HydrophobicContact CD1-CD1 3.97Å; F36-I292 HydrophobicContact CE1-CB 4.27Å; F36-I292 HydrophobicContact CE1-CD1 3.55Å; F36-I292 HydrophobicContact CE1-CG2 4.01Å; F36-I292 HydrophobicContact CE2-CG2 4.34Å; F36-I292 HydrophobicContact CZ-CB 4.28Å; F36-I292 HydrophobicContact CZ-CD1 4.18Å; F36-I292 HydrophobicContact CZ-CG2 3.55Å; I37-I292 HydrophobicContact CB-CD1 4.41Å; I37-I292 HydrophobicContact CG1-CD1 4.21Å; N40-I292 HydrophobicContact CB-CD1 4.15Å; N40-I292 HydrophobicContact CB-CG1 4.24Å; N40-I292 HydrophobicContact CB-CG2 3.66Å; F289-I292 WeakPolarHBondContact O-CB 3.45Å; F289-I292 PolarHBondContact O-N 2.77Å; L290-I292 PolarHBondContact O-N 3.42Å; I292-R296 VanDerWaalsContact O-CB 3.3Å; I292-R296 WeakPolarHBondContact O-CB 3.49Å; I292-R296 PolarHBondContact O-N 3.35Å
293Y98.8Very high98.3Very high0 Ų026.3 Ų26.30%015%0.147CC..Hα-helixtrans-76.7-43.4178.6-69.3-98.5000111.5F22 F36 A255 A261 F289 L290 D291 R296 D297F22-Y293 HydrophobicContact CE2-CD1 4.25Å; F22-Y293 AromaticContact CE2-CE1 3.77Å; F22-Y293 HydrophobicContact CE2-CE1 3.77Å; F22-Y293 AromaticContact CZ-CD1 3.9Å; F22-Y293 HydrophobicContact CZ-CD1 3.9Å; F22-Y293 AromaticContact CZ-CE1 3.89Å; F22-Y293 HydrophobicContact CZ-CE1 3.89Å; F22-Y293 HydrophobicContact CZ-CG 4.26Å; F36-Y293 AromaticContact CE1-CE2 3.88Å; F36-Y293 HydrophobicContact CE1-CE2 3.88Å; F36-Y293 AromaticContact CZ-CE2 3.73Å; F36-Y293 HydrophobicContact CZ-CE2 3.73Å; A255-Y293 HydrophobicContact CB-CE1 4.45Å; A261-Y293 HydrophobicContact CB-CD1 3.7Å; A261-Y293 HydrophobicContact CB-CD2 3.62Å; A261-Y293 HydrophobicContact CB-CE1 4.1Å; A261-Y293 HydrophobicContact CB-CE2 4.05Å; A261-Y293 HydrophobicContact CB-CG 3.43Å; A261-Y293 VanDerWaalsContact CB-CG 3.43Å; F289-Y293 HydrophobicContact CE1-CE2 4.33Å; F289-Y293 HydrophobicContact CE2-CE2 4.03Å; F289-Y293 AromaticContact CZ-CE2 3.76Å; F289-Y293 HydrophobicContact CZ-CE2 3.76Å; L290-Y293 PolarHBondContact O-N 2.92Å; D291-Y293 VanDerWaalsContact C-N 3.26Å; D291-Y293 PolarHBondContact O-N 3.45Å; Y293-R296 PolarHBondContact O-N 3.49Å; Y293-D297 PolarHBondContact O-N 3.03Å
294I98.8Very high98.3Very high0 Ų029.8 Ų29.80%017%0.168CC..Hα-helixtrans-59.7-52178-71.1168.6000110.6A258 L290 D291 R296 D297 I298 L303 A308 I312 N359A258-I294 HydrophobicContact CB-CG1 3.87Å; L290-I294 PolarHBondContact O-N 2.67Å; L290-I294 VanDerWaalsContact O-N 3.12Å; D291-I294 PolarHBondContact O-N 2.99Å; I294-R296 VanDerWaalsContact C-N 3.31Å; I294-R296 PolarHBondContact O-N 2.82Å; I294-D297 PolarHBondContact O-N 3.01Å; I294-D297 VanDerWaalsContact O-N 3.15Å; I294-I298 HydrophobicContact CG2-CD1 3.7Å; I294-I298 HydrophobicContact CG2-CG1 4.36Å; I294-I298 WeakPolarHBondContact O-CG1 3.32Å; I294-I298 PolarHBondContact O-N 3.43Å; I294-L303 HydrophobicContact CG1-CD2 4.44Å; I294-L303 HydrophobicContact CG2-CD2 4.14Å; I294-A308 HydrophobicContact CG2-CB 3.62Å; I294-I312 HydrophobicContact CD1-CD1 3.93Å; I294-I312 HydrophobicContact CD1-CG1 4.31Å; I294-N359 WeakPolarHBondContact CD1-OD1 3.48Å
295Q98.4Very high98.3Very high24 Ų2431.5 Ų31.511%0.11218%0.176CC..Hα-helixtrans-63.2-37.8-178.8-170.258.468.400111.5D291 N299D291-Q295 WeakPolarHBondContact O-CB 3.47Å; D291-Q295 PolarHBondContact O-N 3.02Å; Q295-N299 PolarHBondContact NE2-OD1 3.1Å; Q295-N299 VanDerWaalsContact O-CB 3.3Å; Q295-N299 WeakPolarHBondContact O-CB 3.34Å; Q295-N299 PolarHBondContact O-N 3.26Å; Q295-N299 PolarHBondContact O-ND2 3.36Å; Q295-N299 PolarHBondContact O-OD1 3.47Å
296R98.1Very high98.3Very high26 Ų2636 Ų3610%0.09820%0.197CC..Hα-helixtrans-61.7-46173.6-174.2-167.767.3179.3-1.5111.5A18 F22 E256 I292 Y293 I294 N299 K300A18-R296 PolarHBondContact O-NH1 3.24Å; F22-R296 HydrophobicContact CE1-CB 4.36Å; F22-R296 HydrophobicContact CE1-CG 4.44Å; F22-R296 VanDerWaalsContact CZ-NH1 3.3Å; E256-R296 PolarHBondContact O-NH2 2.75Å; I292-R296 VanDerWaalsContact O-CB 3.3Å; I292-R296 WeakPolarHBondContact O-CB 3.49Å; I292-R296 PolarHBondContact O-N 3.35Å; Y293-R296 PolarHBondContact O-N 3.49Å; I294-R296 VanDerWaalsContact C-N 3.31Å; I294-R296 PolarHBondContact O-N 2.82Å; R296-N299 PolarHBondContact O-N 2.84Å; R296-K300 HydrophobicContact CG-CD 4.44Å; R296-K300 WeakPolarHBondContact O-CG 3.41Å; R296-K300 PolarHBondContact O-N 2.76Å
297D98.4Very high98.3Very high5 Ų539.9 Ų39.93%0.02721%0.214CC..Hα-helixtrans-74.1-33.4-175.8-70.36.9000112N257 A258 Y293 I294 K300 G301 I302 L303N257-D297 WeakPolarHBondContact CA-OD2 3.26Å; N257-D297 VanDerWaalsContact CB-OD2 3.25Å; N257-D297 WeakPolarHBondContact CB-OD2 3.33Å; A258-D297 HydrophobicContact CB-CB 4.35Å; A258-D297 WeakPolarHBondContact CB-OD2 3.26Å; A258-D297 PolarHBondContact N-OD2 3.4Å; Y293-D297 PolarHBondContact O-N 3.03Å; I294-D297 PolarHBondContact O-N 3.01Å; I294-D297 VanDerWaalsContact O-N 3.15Å; D297-K300 PolarHBondContact O-N 3.34Å; D297-G301 PolarHBondContact O-N 3.1Å; D297-I302 HydrophobicContact CB-CB 4.43Å; D297-I302 PolarHBondContact O-N 3.46Å; D297-L303 HydrophobicContact CB-CB 3.94Å; D297-L303 PolarHBondContact O-N 3.4Å
298I98.3Very high98.3Very high39 Ų3939.9 Ų39.920%0.221%0.214CC..Hα-helixtrans-61.1-47.6167.7-70.3172.9000110.4I294 K300 G301 L303 A308I294-I298 HydrophobicContact CG2-CD1 3.7Å; I294-I298 HydrophobicContact CG2-CG1 4.36Å; I294-I298 WeakPolarHBondContact O-CG1 3.32Å; I294-I298 PolarHBondContact O-N 3.43Å; I298-K300 PolarHBondContact O-N 2.95Å; I298-G301 PolarHBondContact O-N 3.16Å; I298-L303 WeakPolarHBondContact CA-O 3.29Å; I298-L303 HydrophobicContact CG1-CB 4.19Å; I298-L303 HydrophobicContact CG1-CD2 4.4Å; I298-L303 HydrophobicContact CG1-CG 4.5Å; I298-A308 HydrophobicContact CD1-CB 4.16Å
299N97.3Very high98.3Very high117 Ų11739.8 Ų39.863%0.62621%0.213SC*.Hα-helixtrans-63-29.1179.5-70.9-13.1000112.8Q295 R296 G301Q295-N299 PolarHBondContact NE2-OD1 3.1Å; Q295-N299 VanDerWaalsContact O-CB 3.3Å; Q295-N299 WeakPolarHBondContact O-CB 3.34Å; Q295-N299 PolarHBondContact O-N 3.26Å; Q295-N299 PolarHBondContact O-ND2 3.36Å; Q295-N299 PolarHBondContact O-OD1 3.47Å; R296-N299 PolarHBondContact O-N 2.84Å; N299-G301 VanDerWaalsContact C-N 3.29Å
300K96.6Very high98.3Very high106 Ų10640.6 Ų40.646%0.46122%0.217SC..THydrogen-bonded Turntrans-80.9-5.9173.8-71.2179.2178.9-176.90113.3R296 D297 I298 I302R296-K300 HydrophobicContact CG-CD 4.44Å; R296-K300 WeakPolarHBondContact O-CG 3.41Å; R296-K300 PolarHBondContact O-N 2.76Å; D297-K300 PolarHBondContact O-N 3.34Å; I298-K300 PolarHBondContact O-N 2.95Å; K300-I302 HydrophobicContact CB-CD1 3.66Å; K300-I302 HydrophobicContact CB-CG1 3.83Å; K300-I302 HydrophobicContact CD-CD1 3.86Å; K300-I302 HydrophobicContact CG-CD1 4.41Å; K300-I302 PolarHBondContact O-N 2.98Å
301G97.1Very high98.3Very high66 Ų6640.9 Ų40.968%0.6822%0.219SC*.THydrogen-bonded Turntrans69.419.6-175.100000113.9D297 I298 N299D297-G301 PolarHBondContact O-N 3.1Å; I298-G301 PolarHBondContact O-N 3.16Å; N299-G301 VanDerWaalsContact C-N 3.29Å
302I96.3Very high98.3Very high119 Ų11940.9 Ų40.961%0.6122%0.218SC*.SBendtrans-86.5-33179.7-61.4169.2000110.5D297 K300D297-I302 HydrophobicContact CB-CB 4.43Å; D297-I302 PolarHBondContact O-N 3.46Å; K300-I302 HydrophobicContact CB-CD1 3.66Å; K300-I302 HydrophobicContact CB-CG1 3.83Å; K300-I302 HydrophobicContact CD-CD1 3.86Å; K300-I302 HydrophobicContact CG-CD1 4.41Å; K300-I302 PolarHBondContact O-N 2.98Å
303L98.1Very high98.3Very high28 Ų2840.6 Ų40.615%0.14722%0.217CC..SBendtrans-121.1136.8-177.4-165.770000109.7A258 I294 D297 I298 K307 A308 L311A258-L303 HydrophobicContact CB-CD2 3.87Å; I294-L303 HydrophobicContact CG1-CD2 4.44Å; I294-L303 HydrophobicContact CG2-CD2 4.14Å; D297-L303 HydrophobicContact CB-CB 3.94Å; D297-L303 PolarHBondContact O-N 3.4Å; I298-L303 WeakPolarHBondContact CA-O 3.29Å; I298-L303 HydrophobicContact CG1-CB 4.19Å; I298-L303 HydrophobicContact CG1-CD2 4.4Å; I298-L303 HydrophobicContact CG1-CG 4.5Å; L303-K307 HydrophobicContact CD1-CB 3.68Å; L303-K307 HydrophobicContact CG-CB 4.4Å; L303-A308 HydrophobicContact CD2-CB 3.81Å; L303-A308 HydrophobicContact CG-CB 4.31Å; L303-L311 HydrophobicContact CD1-CD1 4.29Å; L303-L311 HydrophobicContact CD2-CD1 4.24Å
304T98.6Very high98.3Very high76 Ų7640.6 Ų40.647%0.46622%0.217SC..  trans-90.9163.516961.50000110E306 K307 A308T304-E306 VanDerWaalsContact C-N 3.33Å; T304-E306 PolarHBondContact O-N 2.88Å; T304-K307 PolarHBondContact O-N 3.29Å; T304-K307 WeakPolarHBondContact OG1-CB 3.47Å; T304-K307 WeakPolarHBondContact OG1-CG 3.2Å; T304-K307 PolarHBondContact OG1-N 2.87Å; T304-A308 PolarHBondContact O-N 3.16Å
305E98.7Very high98.3Very high37 Ų3740.7 Ų40.717%0.17322%0.217CC..Hα-helixtrans-61.3-41.3175-174.755.9-141.500112.1F50 A52 K307 A308 Q309 R362F50-E305 HydrophobicContact CD2-CG 4.14Å; F50-E305 WeakPolarHBondContact CD2-OE1 3.37Å; F50-E305 WeakPolarHBondContact CE2-OE1 3.46Å; F50-E305 VanDerWaalsContact O-CG 3.27Å; F50-E305 WeakPolarHBondContact O-CG 3.49Å; A52-E305 HydrophobicContact CB-CG 4.29Å; E305-K307 VanDerWaalsContact C-N 3.33Å; E305-K307 PolarHBondContact O-N 3.01Å; E305-A308 WeakPolarHBondContact O-CB 3.45Å; E305-A308 PolarHBondContact O-N 3.5Å; E305-A308 VanDerWaalsContact O-N 3.11Å; E305-Q309 PolarHBondContact O-N 3.03Å; E305-R362 IonicContact OE1-CZ 2.71Å; E305-R362 IonicContact OE1-NE 3.48Å; E305-R362 PolarHBondContact OE1-NE 2.79Å; E305-R362 IonicContact OE1-NH2 2.77Å; E305-R362 PolarHBondContact OE1-NH2 3.43Å; E305-R362 IonicContact OE2-CZ 2.73Å; E305-R362 IonicContact OE2-NE 2.66Å; E305-R362 IonicContact OE2-NH2 3.72Å; E305-R362 PolarHBondContact OE2-NH2 2.83Å
306E98.6Very high98.3Very high100 Ų10039.5 Ų39.547%0.46721%0.212SC..Hα-helixtrans-55.8-45.2173179.5-173.1-150.900112.1A52 T55 T304 Q309 E310A52-E306 HydrophobicContact CB-CB 4.21Å; T55-E306 HydrophobicContact CG2-CG 3.65Å; T304-E306 VanDerWaalsContact C-N 3.33Å; T304-E306 PolarHBondContact O-N 2.88Å; E306-Q309 PolarHBondContact O-N 3.33Å; E306-E310 PolarHBondContact O-N 3.33Å
307K98.7Very high98.4Very high84 Ų8438.3 Ų38.337%0.36521%0.207SC..Hα-helixtrans-75.1-24.2177.7-68.6-62.1-178.3-176.60113.3L303 T304 E305 E310 L311L303-K307 HydrophobicContact CD1-CB 3.68Å; L303-K307 HydrophobicContact CG-CB 4.4Å; T304-K307 PolarHBondContact O-N 3.29Å; T304-K307 WeakPolarHBondContact OG1-CB 3.47Å; T304-K307 WeakPolarHBondContact OG1-CG 3.2Å; T304-K307 PolarHBondContact OG1-N 2.87Å; E305-K307 VanDerWaalsContact C-N 3.33Å; E305-K307 PolarHBondContact O-N 3.01Å; K307-E310 WeakPolarHBondContact CD-OE2 3.4Å; K307-E310 IonicContact NZ-OE1 3.37Å; K307-E310 PolarHBondContact NZ-OE1 3.29Å; K307-E310 IonicContact NZ-OE2 2.83Å; K307-E310 PolarHBondContact NZ-OE2 2.95Å; K307-L311 WeakPolarHBondContact O-CG 3.4Å; K307-L311 PolarHBondContact O-N 2.79Å
308A98.9Very high98.4Very high0 Ų038 Ų380%021%0.206CC..Hα-helixtrans-67.7-44.8168.300000111.1I294 I298 L303 T304 E305 L311 I312I294-A308 HydrophobicContact CG2-CB 3.62Å; I298-A308 HydrophobicContact CD1-CB 4.16Å; L303-A308 HydrophobicContact CD2-CB 3.81Å; L303-A308 HydrophobicContact CG-CB 4.31Å; T304-A308 PolarHBondContact O-N 3.16Å; E305-A308 WeakPolarHBondContact O-CB 3.45Å; E305-A308 PolarHBondContact O-N 3.5Å; E305-A308 VanDerWaalsContact O-N 3.11Å; A308-L311 PolarHBondContact O-N 3.34Å; A308-I312 PolarHBondContact O-N 3.04Å
309Q98.9Very high98.4Very high1 Ų136.2 Ų36.21%0.00520%0.197CC..Hα-helixtrans-62.6-42.4175.7-171.162.846.500111.4A52 E305 E306 L311 I312 D313 R362 N369A52-Q309 HydrophobicContact CB-CB 4.36Å; E305-Q309 PolarHBondContact O-N 3.03Å; E306-Q309 PolarHBondContact O-N 3.33Å; Q309-L311 VanDerWaalsContact C-N 3.28Å; Q309-L311 PolarHBondContact O-N 3.12Å; Q309-I312 PolarHBondContact O-N 2.73Å; Q309-D313 PolarHBondContact NE2-OD1 3.09Å; Q309-D313 WeakPolarHBondContact O-CB 3.39Å; Q309-D313 PolarHBondContact O-N 3.31Å; Q309-R362 PolarHBondContact NE2-O 3.11Å; Q309-R362 VanDerWaalsContact OE1-CG 3.25Å; Q309-N369 WeakPolarHBondContact CG-ND2 3.35Å
310E98.9Very high98.4Very high18 Ų1831.3 Ų31.38%0.08417%0.169CC..Hα-helixtrans-54.8-40.6175.2-174.5-179-105.900112.7T55 A106 E306 K307 I312 H314T55-E310 HydrophobicContact CG2-CB 3.85Å; T55-E310 HydrophobicContact CG2-CG 4.11Å; T55-E310 WeakPolarHBondContact CG2-OE1 3.42Å; T55-E310 PolarHBondContact OG1-OE1 3.26Å; A106-E310 HydrophobicContact CB-CG 4.15Å; E306-E310 PolarHBondContact O-N 3.33Å; K307-E310 WeakPolarHBondContact CD-OE2 3.4Å; K307-E310 IonicContact NZ-OE1 3.37Å; K307-E310 PolarHBondContact NZ-OE1 3.29Å; K307-E310 IonicContact NZ-OE2 2.83Å; K307-E310 PolarHBondContact NZ-OE2 2.95Å; E310-I312 PolarHBondContact O-N 2.81Å; E310-H314 VanDerWaalsContact O-CB 3.32Å; E310-H314 WeakPolarHBondContact O-CB 3.43Å; E310-H314 PolarHBondContact O-CD2 3.11Å; E310-H314 VanDerWaalsContact O-CG 3.24Å; E310-H314 PolarHBondContact O-N 3.22Å
311L98.9Very high98.5Very high6 Ų626.7 Ų26.73%0.03115%0.15CC..Hα-helixtrans-63.9-41176.5-67.1173000112.1A106 I107 A258 K259 V262 L303 K307 A308 Q309 L315A106-L311 HydrophobicContact CB-CD2 4.02Å; I107-L311 HydrophobicContact CD1-CD2 3.98Å; I107-L311 HydrophobicContact CG1-CD2 4.36Å; A258-L311 HydrophobicContact CB-CD1 4.13Å; K259-L311 HydrophobicContact CB-CD1 4.4Å; K259-L311 HydrophobicContact CB-CD2 3.94Å; K259-L311 HydrophobicContact CG-CD2 3.97Å; V262-L311 HydrophobicContact CG2-CB 4.38Å; L303-L311 HydrophobicContact CD1-CD1 4.29Å; L303-L311 HydrophobicContact CD2-CD1 4.24Å; K307-L311 WeakPolarHBondContact O-CG 3.4Å; K307-L311 PolarHBondContact O-N 2.79Å; A308-L311 PolarHBondContact O-N 3.34Å; Q309-L311 VanDerWaalsContact C-N 3.28Å; Q309-L311 PolarHBondContact O-N 3.12Å; L311-L315 WeakPolarHBondContact O-CB 3.37Å; L311-L315 PolarHBondContact O-N 3.34Å
312I98.9Very high98.6Very high0 Ų023.9 Ų23.90%012%0.119CC..Hα-helixtrans-73.3-42.6179.8-59.2-53000110.9I294 A308 Q309 E310 H314 L315 V316 N359 R362 F363 T366I294-I312 HydrophobicContact CD1-CD1 3.93Å; I294-I312 HydrophobicContact CD1-CG1 4.31Å; A308-I312 PolarHBondContact O-N 3.04Å; Q309-I312 PolarHBondContact O-N 2.73Å; E310-I312 PolarHBondContact O-N 2.81Å; I312-H314 VanDerWaalsContact C-N 3.34Å; I312-H314 PolarHBondContact O-N 2.88Å; I312-L315 PolarHBondContact O-N 3.29Å; I312-V316 HydrophobicContact CG2-CG2 4.44Å; I312-V316 WeakPolarHBondContact O-CB 3.46Å; I312-V316 WeakPolarHBondContact O-CG2 3.35Å; I312-V316 PolarHBondContact O-N 2.9Å; I312-N359 WeakPolarHBondContact CD1-OD1 3.43Å; I312-N359 WeakPolarHBondContact CG1-OD1 3.12Å; I312-R362 HydrophobicContact CB-CB 4.41Å; I312-R362 HydrophobicContact CG1-CB 4.18Å; I312-R362 HydrophobicContact CG2-CB 4.26Å; I312-F363 HydrophobicContact CD1-CE2 3.95Å; I312-F363 HydrophobicContact CD1-CZ 4Å; I312-F363 HydrophobicContact CG2-CD1 3.78Å; I312-F363 HydrophobicContact CG2-CD2 4.14Å; I312-F363 HydrophobicContact CG2-CE1 3.85Å; I312-F363 HydrophobicContact CG2-CE2 4.19Å; I312-F363 HydrophobicContact CG2-CG 3.93Å; I312-F363 HydrophobicContact CG2-CZ 4.07Å; I312-T366 HydrophobicContact CG2-CG2 3.94Å
313D98.9Very high98.6Very high1 Ų119.2 Ų19.21%0.0059%0.094CC..Hα-helixtrans-57.6-48174.2-73-13.5000110.2T58 Q309 V316 M317 T366 N369 M370T58-D313 HydrophobicContact CG2-CB 3.83Å; Q309-D313 PolarHBondContact NE2-OD1 3.09Å; Q309-D313 WeakPolarHBondContact O-CB 3.39Å; Q309-D313 PolarHBondContact O-N 3.31Å; D313-V316 PolarHBondContact O-N 2.9Å; D313-M317 VanDerWaalsContact O-CB 3.24Å; D313-M317 WeakPolarHBondContact O-CB 3.16Å; D313-M317 PolarHBondContact O-N 2.85Å; D313-T366 WeakPolarHBondContact OD1-CG2 3.27Å; D313-N369 PolarHBondContact OD2-ND2 3Å; D313-N369 VanDerWaalsContact OD2-ND2 3.11Å; D313-M370 HydrophobicContact CB-CE 3.89Å; D313-M370 HydrophobicContact CB-SD 4.14Å; D313-M370 VanDerWaalsContact O-CE 3.31Å; D313-M370 WeakPolarHBondContact O-CE 3.02Å
314H98.9Very high98.5Very high0 Ų018.1 Ų18.10%09%0.089CC..Hα-helixtrans-70.2-35.1-179.1-70.1-170.9000112.7T58 E104 A106 I107 E310 I312 K318T58-H314 WeakPolarHBondContact CA-NE2 3.49Å; T58-H314 PolarHBondContact OG1-NE2 3.38Å; E104-H314 PolarHBondContact O-CE1 3.3Å; A106-H314 VanDerWaalsContact CB-ND1 3.26Å; A106-H314 WeakPolarHBondContact CB-ND1 3.24Å; A106-H314 PolarHBondContact N-ND1 3.11Å; I107-H314 HydrophobicContact CB-CB 3.98Å; I107-H314 HydrophobicContact CG1-CB 4.12Å; E310-H314 VanDerWaalsContact O-CB 3.32Å; E310-H314 WeakPolarHBondContact O-CB 3.43Å; E310-H314 PolarHBondContact O-CD2 3.11Å; E310-H314 VanDerWaalsContact O-CG 3.24Å; E310-H314 PolarHBondContact O-N 3.22Å; I312-H314 VanDerWaalsContact C-N 3.34Å; I312-H314 PolarHBondContact O-N 2.88Å; H314-K318 WeakPolarHBondContact O-CG 3.4Å; H314-K318 PolarHBondContact O-N 2.89Å; H314-K318 VanDerWaalsContact O-N 3.16Å
315L98.9Very high98.4Very high1 Ų115.5 Ų15.51%0.0058%0.075CC..Hα-helixtrans-59.7-53.8169.7171.363000110.5V262 Y266 L290 L311 I312 M317 K318 L319 F363V262-L315 HydrophobicContact CG1-CB 3.86Å; V262-L315 HydrophobicContact CG1-CD2 4.04Å; V262-L315 HydrophobicContact CG1-CG 4.35Å; Y266-L315 HydrophobicContact CD2-CD1 3.84Å; Y266-L315 HydrophobicContact CG-CD1 4.04Å; L290-L315 HydrophobicContact CD1-CD2 4Å; L311-L315 WeakPolarHBondContact O-CB 3.37Å; L311-L315 PolarHBondContact O-N 3.34Å; I312-L315 PolarHBondContact O-N 3.29Å; L315-M317 VanDerWaalsContact C-N 3.27Å; L315-M317 PolarHBondContact O-N 3.41Å; L315-K318 WeakPolarHBondContact O-CB 3.25Å; L315-K318 PolarHBondContact O-N 2.94Å; L315-L319 HydrophobicContact CG-CD1 4.47Å; L315-L319 WeakPolarHBondContact O-CG 3.47Å; L315-L319 PolarHBondContact O-N 2.66Å; L315-L319 VanDerWaalsContact O-N 3.08Å; L315-F363 HydrophobicContact CD2-CE1 4.08Å; L315-F363 HydrophobicContact CD2-CZ 3.84Å
316V98.9Very high98.2Very high0 Ų014.3 Ų14.30%07%0.068CC..Hα-helixtrans-60.8-38.5-179.3164.30000111.3I312 D313 K318 L319 R320 F363 T366 M370 P376I312-V316 HydrophobicContact CG2-CG2 4.44Å; I312-V316 WeakPolarHBondContact O-CB 3.46Å; I312-V316 WeakPolarHBondContact O-CG2 3.35Å; I312-V316 PolarHBondContact O-N 2.9Å; D313-V316 PolarHBondContact O-N 2.9Å; V316-K318 VanDerWaalsContact C-N 3.27Å; V316-K318 PolarHBondContact O-N 3.3Å; V316-L319 WeakPolarHBondContact O-CA 3.38Å; V316-L319 WeakPolarHBondContact O-CB 3.27Å; V316-L319 PolarHBondContact O-N 3.24Å; V316-R320 HydrophobicContact CG1-CG 4.41Å; V316-R320 WeakPolarHBondContact O-CG 3.44Å; V316-R320 PolarHBondContact O-N 3.18Å; V316-F363 HydrophobicContact CG2-CD1 3.74Å; V316-F363 HydrophobicContact CG2-CE1 3.79Å; V316-T366 HydrophobicContact CB-CG2 4.03Å; V316-T366 HydrophobicContact CG1-CG2 4.21Å; V316-T366 HydrophobicContact CG2-CG2 3.79Å; V316-M370 HydrophobicContact CB-CE 4.02Å; V316-M370 HydrophobicContact CG1-CE 3.75Å; V316-P376 HydrophobicContact CG1-CG 4.3Å; V316-P376 HydrophobicContact CG2-CG 4.21Å
317M98.7Very high97.9Very high0 Ų010 Ų100%05%0.048CC..Hα-helixtrans-57.6-41.2174.1-169.9-179.7-59.400111.4T58 L61 W62 L65 I97 D313 L315 R320 M321 M370T58-M317 HydrophobicContact CG2-CE 4.34Å; L61-M317 HydrophobicContact CB-CE 3.93Å; L61-M317 HydrophobicContact CB-SD 3.64Å; W62-M317 HydrophobicContact CB-CE 3.78Å; W62-M317 HydrophobicContact CE3-CE 4.38Å; W62-M317 HydrophobicContact CE3-CG 4.17Å; L65-M317 HydrophobicContact CD2-CG 3.71Å; I97-M317 HydrophobicContact CD1-CG 4.2Å; I97-M317 HydrophobicContact CD1-SD 3.48Å; I97-M317 WeakPolarHBondContact CD1-SD 3.11Å; D313-M317 VanDerWaalsContact O-CB 3.24Å; D313-M317 WeakPolarHBondContact O-CB 3.16Å; D313-M317 PolarHBondContact O-N 2.85Å; L315-M317 VanDerWaalsContact C-N 3.27Å; L315-M317 PolarHBondContact O-N 3.41Å; M317-R320 WeakPolarHBondContact O-CB 3.5Å; M317-R320 PolarHBondContact O-N 3.34Å; M317-M321 VanDerWaalsContact O-CG 3.27Å; M317-M321 WeakPolarHBondContact O-CG 3.26Å; M317-M321 PolarHBondContact O-N 2.82Å; M317-M370 HydrophobicContact CB-SD 4.16Å; M317-M370 HydrophobicContact CE-SD 3.65Å
318K98.8Very high97.4Very high0 Ų08.2 Ų8.20%05%0.045CC..Hα-helixtrans-67.3-35.7173.6-66.6-49.8-171-70.90113.3E105 I107 G109 I110 Y266 H314 L315 V316 R320 M321E105-K318 WeakPolarHBondContact OE2-CE 3.17Å; E105-K318 IonicContact OE2-NZ 2.88Å; E105-K318 PolarHBondContact OE2-NZ 3.32Å; I107-K318 WeakPolarHBondContact O-CE 3.36Å; I107-K318 PolarHBondContact O-NZ 2.99Å; G109-K318 VanDerWaalsContact O-CD 3.26Å; G109-K318 WeakPolarHBondContact O-CD 3.45Å; G109-K318 WeakPolarHBondContact O-CE 3.09Å; I110-K318 HydrophobicContact CG2-CD 4.24Å; Y266-K318 HydrophobicContact CE1-CB 3.97Å; Y266-K318 HydrophobicContact CE1-CG 3.92Å; Y266-K318 HydrophobicContact CE2-CB 3.78Å; Y266-K318 VanDerWaalsContact CZ-CB 3.48Å; Y266-K318 WeakPolarHBondContact OH-CB 3.36Å; H314-K318 WeakPolarHBondContact O-CG 3.4Å; H314-K318 PolarHBondContact O-N 2.89Å; H314-K318 VanDerWaalsContact O-N 3.16Å; L315-K318 WeakPolarHBondContact O-CB 3.25Å; L315-K318 PolarHBondContact O-N 2.94Å; V316-K318 VanDerWaalsContact C-N 3.27Å; V316-K318 PolarHBondContact O-N 3.3Å; K318-R320 VanDerWaalsContact C-N 3.31Å; K318-M321 HydrophobicContact CD-SD 3.91Å; K318-M321 PolarHBondContact O-N 3.27Å
319L98.7Very high97Very high1 Ų110.7 Ų10.71%0.0056%0.063CC..Hα-helixtrans-66.2-34.6174.3-55.4-178.8000111.9Y266 Y269 I283 L315 V316 M321 V322 A341 L343 P376Y266-L319 HydrophobicContact CD2-CD2 4.4Å; Y266-L319 HydrophobicContact CE2-CD2 4.24Å; Y269-L319 HydrophobicContact CD1-CD2 3.71Å; Y269-L319 HydrophobicContact CE1-CD2 3.43Å; Y269-L319 VanDerWaalsContact CE1-CD2 3.43Å; I283-L319 HydrophobicContact CD1-CD1 3.9Å; I283-L319 HydrophobicContact CD1-CD2 3.88Å; I283-L319 HydrophobicContact CG2-CD1 4.36Å; L315-L319 HydrophobicContact CG-CD1 4.47Å; L315-L319 WeakPolarHBondContact O-CG 3.47Å; L315-L319 PolarHBondContact O-N 2.66Å; L315-L319 VanDerWaalsContact O-N 3.08Å; V316-L319 WeakPolarHBondContact O-CA 3.38Å; V316-L319 WeakPolarHBondContact O-CB 3.27Å; V316-L319 PolarHBondContact O-N 3.24Å; L319-M321 PolarHBondContact O-N 2.92Å; L319-V322 WeakPolarHBondContact O-CG2 3.24Å; L319-V322 PolarHBondContact O-N 2.71Å; L319-A341 HydrophobicContact CB-CB 4.46Å; L319-L343 HydrophobicContact CD1-CD1 4.35Å; L319-P376 HydrophobicContact CB-CB 4.29Å; L319-P376 HydrophobicContact CD1-CB 3.88Å; L319-P376 HydrophobicContact CD1-CG 4.07Å
320R98Very high96.7Very high13 Ų1310.9 Ų10.95%0.0496%0.063CC..THydrogen-bonded Turntrans-68.3-10.4173.4-71.7176-177-159.94.1114.2W62 V316 M317 K318 T366 M370 G371 S373 E375W62-R320 VanDerWaalsContact CH2-NH1 3.33Å; V316-R320 HydrophobicContact CG1-CG 4.41Å; V316-R320 WeakPolarHBondContact O-CG 3.44Å; V316-R320 PolarHBondContact O-N 3.18Å; M317-R320 WeakPolarHBondContact O-CB 3.5Å; M317-R320 PolarHBondContact O-N 3.34Å; K318-R320 VanDerWaalsContact C-N 3.31Å; R320-T366 PolarHBondContact NH2-O 2.93Å; R320-T366 VanDerWaalsContact NH2-O 3.13Å; R320-M370 VanDerWaalsContact NH1-CB 3.34Å; R320-M370 PolarHBondContact NH1-O 3.44Å; R320-G371 PolarHBondContact NH1-O 3.13Å; R320-G371 PolarHBondContact NH2-O 2.85Å; R320-G371 VanDerWaalsContact NH2-O 3.1Å; R320-S373 VanDerWaalsContact NE-CB 3.32Å; R320-S373 PolarHBondContact NE-OG 3.06Å; R320-E375 WeakPolarHBondContact CG-O 3.19Å; R320-E375 PolarHBondContact NE-O 2.91Å
321M98.2Very high96.2Very high10 Ų1012.2 Ų12.25%0.0497%0.071CC..THydrogen-bonded Turntrans-101.9-4.3-178.3-68.6170.267.500113.9L65 I97 I110 P115 L116 M317 K318 L319 K323L65-M321 HydrophobicContact CD1-CE 4.46Å; L65-M321 HydrophobicContact CD1-CG 3.72Å; L65-M321 HydrophobicContact CD1-SD 4.25Å; L65-M321 HydrophobicContact CD2-CG 3.52Å; L65-M321 HydrophobicContact CD2-SD 3.95Å; L65-M321 HydrophobicContact CG-CG 4.3Å; I97-M321 HydrophobicContact CD1-SD 4Å; I97-M321 HydrophobicContact CG1-CE 3.79Å; I97-M321 HydrophobicContact CG1-SD 3.76Å; I110-M321 HydrophobicContact CG2-CE 3.64Å; P115-M321 HydrophobicContact CB-CE 3.38Å; L116-M321 HydrophobicContact CD2-CB 4.11Å; L116-M321 HydrophobicContact CD2-CG 4.24Å; M317-M321 VanDerWaalsContact O-CG 3.27Å; M317-M321 WeakPolarHBondContact O-CG 3.26Å; M317-M321 PolarHBondContact O-N 2.82Å; K318-M321 HydrophobicContact CD-SD 3.91Å; K318-M321 PolarHBondContact O-N 3.27Å; L319-M321 PolarHBondContact O-N 2.92Å; M321-K323 PolarHBondContact O-N 3.21Å
322V98.3Very high95.6Very high6 Ų617.1 Ų17.14%0.0369%0.094CC..  trans-67.8130.3-178.4-176.90000109.6Q111 Y269 I273 L319 F324 V339Q111-V322 VanDerWaalsContact OE1-CA 3.31Å; Y269-V322 HydrophobicContact CE1-CG2 4.18Å; I273-V322 HydrophobicContact CB-CG1 4.26Å; I273-V322 HydrophobicContact CD1-CB 4.31Å; I273-V322 HydrophobicContact CD1-CG1 3.91Å; I273-V322 HydrophobicContact CD1-CG2 3.49Å; I273-V322 VanDerWaalsContact CD1-CG2 3.49Å; I273-V322 HydrophobicContact CG2-CG1 4.15Å; L319-V322 WeakPolarHBondContact O-CG2 3.24Å; L319-V322 PolarHBondContact O-N 2.71Å; V322-F324 HydrophobicContact CG1-CE2 3.94Å; V322-F324 HydrophobicContact CG1-CZ 4.18Å; V322-V339 HydrophobicContact CB-CG1 3.91Å; V322-V339 HydrophobicContact CB-CG2 4.09Å; V322-V339 HydrophobicContact CG1-CB 4.46Å; V322-V339 HydrophobicContact CG1-CG1 3.52Å; V322-V339 HydrophobicContact CG1-CG2 4.05Å; V322-V339 VanDerWaalsContact O-CG2 3.27Å; V322-V339 WeakPolarHBondContact O-CG2 3.11Å
323K96.8Very high95Very high21 Ų2117.8 Ų17.89%0.09110%0.098CC..  trans-143.4148.5-178.7-62.7-68.2-173.1167.10111E72 Q111 L116 R118 M321 D337E72-K323 VanDerWaalsContact OE1-CE 3.27Å; E72-K323 WeakPolarHBondContact OE1-CE 3.27Å; E72-K323 IonicContact OE1-NZ 3.7Å; E72-K323 PolarHBondContact OE1-NZ 3.17Å; E72-K323 VanDerWaalsContact OE2-CE 3.3Å; E72-K323 WeakPolarHBondContact OE2-CE 3.31Å; E72-K323 IonicContact OE2-NZ 2.77Å; E72-K323 PolarHBondContact OE2-NZ 3.07Å; Q111-K323 PolarHBondContact NE2-O 3.44Å; Q111-K323 VanDerWaalsContact NE2-O 3.08Å; Q111-K323 PolarHBondContact OE1-O 3.22Å; Q111-K323 VanDerWaalsContact OE1-O 3.13Å; L116-K323 HydrophobicContact CD2-CG 4.19Å; R118-K323 HydrophobicContact CG-CB 3.96Å; M321-K323 PolarHBondContact O-N 3.21Å; K323-D337 WeakPolarHBondContact CD-OD2 3.31Å; K323-D337 IonicContact NZ-OD2 3.81Å; K323-D337 PolarHBondContact NZ-OD2 2.77Å
324F97.1Very high94.6Very high6 Ų617.9 Ų17.93%0.02610%0.098CC..  trans-131.5141.5175.5-67.6-67.2000111.3R118 M121 I273 Q276 N277 M281 V322 R326 V339R118-F324 WeakPolarHBondContact CD-O 3.47Å; R118-F324 PolarHBondContact NH1-O 3.06Å; M121-F324 HydrophobicContact CE-CD1 4.16Å; M121-F324 HydrophobicContact CE-CE1 3.86Å; M121-F324 HydrophobicContact SD-CD1 4.25Å; M121-F324 HydrophobicContact SD-CE1 4.23Å; I273-F324 HydrophobicContact CB-CZ 4.04Å; I273-F324 HydrophobicContact CG2-CZ 4.21Å; Q276-F324 WeakPolarHBondContact O-CE1 3.4Å; Q276-F324 WeakPolarHBondContact O-CZ 3.32Å; N277-F324 HydrophobicContact CB-CD1 3.59Å; N277-F324 HydrophobicContact CB-CE1 3.99Å; N277-F324 HydrophobicContact CB-CG 4.13Å; M281-F324 HydrophobicContact CB-CE2 4.48Å; M281-F324 HydrophobicContact CG-CE2 3.74Å; M281-F324 HydrophobicContact CG-CZ 3.75Å; V322-F324 HydrophobicContact CG1-CE2 3.94Å; V322-F324 HydrophobicContact CG1-CZ 4.18Å; F324-R326 PolarHBondContact O-N 3.18Å; F324-V339 HydrophobicContact CE2-CG1 4.34Å
325A95.3Very high94Very high21 Ų2118.2 Ų18.217%0.17410%0.1CC..  trans-66.2123.7169.100000109.4M81 R118M81-A325 HydrophobicContact CE-CB 3.54Å; R118-A325 HydrophobicContact CB-CB 4.27Å
326R94.3Very high93.4Very high11 Ų1118.7 Ų18.74%0.04211%0.106CC..  trans-128.7146.6-177.9-58.7-58.7-171.9-175.32110.5S132 N277 G278 F324 Y330 N331S132-R326 PolarHBondContact OG-O 2.7Å; N277-R326 PolarHBondContact O-NH1 3.13Å; G278-R326 PolarHBondContact O-NH2 2.95Å; F324-R326 PolarHBondContact O-N 3.18Å; R326-Y330 HydrophobicContact CB-CD1 3.69Å; R326-Y330 HydrophobicContact CB-CE1 4.38Å; R326-Y330 HydrophobicContact CB-CG 4.13Å; R326-Y330 VanDerWaalsContact CD-CE1 3.48Å; R326-Y330 HydrophobicContact CG-CD1 3.53Å; R326-Y330 HydrophobicContact CG-CE1 3.71Å; R326-Y330 HydrophobicContact CG-CG 4.22Å; R326-Y330 PolarHBondContact NH2-OH 2.88Å; R326-N331 VanDerWaalsContact CB-OD1 3.26Å; R326-N331 WeakPolarHBondContact CB-OD1 3.43Å
327I93Very high93.1Very high9 Ų920.6 Ų20.65%0.04612%0.116CC..  trans-81.9158.2174.359.1176.6000110.5M128 E131 S132 S329 Y330 N331M128-I327 HydrophobicContact CB-CG2 3.79Å; M128-I327 HydrophobicContact CG-CD1 3.76Å; M128-I327 HydrophobicContact CG-CG2 4.08Å; M128-I327 VanDerWaalsContact O-CG2 3.31Å; M128-I327 WeakPolarHBondContact O-CG2 3.48Å; E131-I327 HydrophobicContact CB-CG2 4.07Å; E131-I327 HydrophobicContact CG-CG2 4.16Å; S132-I327 WeakPolarHBondContact OG-CG2 3.43Å; S132-I327 PolarHBondContact OG-N 2.75Å; I327-S329 VanDerWaalsContact C-N 3.29Å; I327-S329 WeakPolarHBondContact CD1-OG 3.44Å; I327-S329 PolarHBondContact O-N 2.73Å; I327-Y330 WeakPolarHBondContact O-CB 3.43Å; I327-Y330 PolarHBondContact O-N 3.03Å; I327-N331 PolarHBondContact O-N 2.92Å
328P88.9Confident92.9Very high47 Ų4721 Ų2131%0.30512%0.118SC..Hα-helixtrans-53.2-42.5179.5-28.436.2000113.9R135 Y330 N331 E332R135-P328 HydrophobicContact CG-CG 4.4Å; P328-Y330 PolarHBondContact O-N 2.89Å; P328-N331 PolarHBondContact O-N 2.89Å; P328-N331 VanDerWaalsContact O-N 3.08Å; P328-E332 PolarHBondContact O-N 2.91Å
329S89.7Confident92.7Very high52 Ų5221.1 Ų21.136%0.36412%0.119SC..Hα-helixtrans-66.2-24.2179.364.80000113.6I327 L333I327-S329 VanDerWaalsContact C-N 3.29Å; I327-S329 WeakPolarHBondContact CD1-OG 3.44Å; I327-S329 PolarHBondContact O-N 2.73Å; S329-L333 WeakPolarHBondContact O-CD1 3.45Å; S329-L333 WeakPolarHBondContact O-CG 3.34Å
330Y92.8Very high92.7Very high5 Ų521.1 Ų21.12%0.0212%0.119CC..Hα-helixtrans-71.3-46.8171.2-179.4-80.1000109.9Y183 A279 R326 I327 P328 E332 L333 F334Y183-Y330 AromaticContact CD1-CD2 3.63Å; Y183-Y330 HydrophobicContact CD1-CD2 3.63Å; Y183-Y330 AromaticContact CD1-CE2 3.95Å; Y183-Y330 HydrophobicContact CD1-CE2 3.95Å; Y183-Y330 HydrophobicContact CD2-CD2 4.36Å; Y183-Y330 AromaticContact CD2-CE2 3.84Å; Y183-Y330 HydrophobicContact CD2-CE2 3.84Å; Y183-Y330 HydrophobicContact CE1-CD2 4.18Å; Y183-Y330 HydrophobicContact CE1-CE2 4.37Å; Y183-Y330 HydrophobicContact CE2-CE2 4.31Å; Y183-Y330 AromaticContact CG-CD2 3.75Å; Y183-Y330 HydrophobicContact CG-CD2 3.75Å; Y183-Y330 AromaticContact CG-CE2 3.68Å; Y183-Y330 HydrophobicContact CG-CE2 3.68Å; A279-Y330 WeakPolarHBondContact CA-OH 3.46Å; R326-Y330 HydrophobicContact CB-CD1 3.69Å; R326-Y330 HydrophobicContact CB-CE1 4.38Å; R326-Y330 HydrophobicContact CB-CG 4.13Å; R326-Y330 VanDerWaalsContact CD-CE1 3.48Å; R326-Y330 HydrophobicContact CG-CD1 3.53Å; R326-Y330 HydrophobicContact CG-CE1 3.71Å; R326-Y330 HydrophobicContact CG-CG 4.22Å; R326-Y330 PolarHBondContact NH2-OH 2.88Å; I327-Y330 WeakPolarHBondContact O-CB 3.43Å; I327-Y330 PolarHBondContact O-N 3.03Å; P328-Y330 PolarHBondContact O-N 2.89Å; Y330-E332 PolarHBondContact O-N 3.47Å; Y330-L333 PolarHBondContact O-N 2.79Å; Y330-F334 HydrophobicContact CD1-CB 4.04Å; Y330-F334 HydrophobicContact CD1-CD2 4.01Å; Y330-F334 HydrophobicContact CD1-CG 4.48Å; Y330-F334 AromaticContact CD2-CD2 3.62Å; Y330-F334 HydrophobicContact CD2-CD2 3.62Å; Y330-F334 AromaticContact CD2-CE2 3.97Å; Y330-F334 HydrophobicContact CD2-CE2 3.97Å; Y330-F334 HydrophobicContact CE1-CB 3.57Å; Y330-F334 AromaticContact CE1-CD2 3.82Å; Y330-F334 HydrophobicContact CE1-CD2 3.82Å; Y330-F334 AromaticContact CE1-CG 4Å; Y330-F334 HydrophobicContact CE1-CG 4Å; Y330-F334 AromaticContact CE2-CD2 3.42Å; Y330-F334 HydrophobicContact CE2-CD2 3.42Å; Y330-F334 VanDerWaalsContact CE2-CD2 3.42Å; Y330-F334 AromaticContact CE2-CE2 3.74Å; Y330-F334 HydrophobicContact CE2-CE2 3.74Å; Y330-F334 HydrophobicContact CE2-CG 4.2Å; Y330-F334 AromaticContact CG-CD2 3.9Å; Y330-F334 HydrophobicContact CG-CD2 3.9Å; Y330-F334 AromaticContact CZ-CD2 3.52Å; Y330-F334 AromaticContact CZ-CG 3.84Å; Y330-F334 PolarHBondContact O-N 2.71Å
331N88.9Confident92.7Very high46 Ų4620.5 Ų20.525%0.24612%0.117CC..Hα-helixtrans-63.8-26.7-178.8-65-11.2000112.9R326 I327 P328 F334 S335R326-N331 VanDerWaalsContact CB-OD1 3.26Å; R326-N331 WeakPolarHBondContact CB-OD1 3.43Å; I327-N331 PolarHBondContact O-N 2.92Å; P328-N331 PolarHBondContact O-N 2.89Å; P328-N331 VanDerWaalsContact O-N 3.08Å; N331-F334 CarbonylContact O-C 3.14Å; N331-S335 WeakPolarHBondContact O-CA 3.27Å
332E86.2Confident92.7Very high109 Ų10920 Ų2051%0.50912%0.115SC..Hα-helixtrans-69.4-36.3171.1-71175.9-177.800112.8P328 Y330 T614 V618P328-E332 PolarHBondContact O-N 2.91Å; Y330-E332 PolarHBondContact O-N 3.47Å; E332-T614 WeakPolarHBondContact O-CB 3.2Å; E332-T614 WeakPolarHBondContact O-CG2 3.08Å; E332-V618 HydrophobicContact CB-CG2 4.17Å; E332-V618 WeakPolarHBondContact O-CG2 3.39Å
333L86.6Confident92.8Very high15 Ų1519.8 Ų19.88%0.07911%0.113CC..Hα-helixtrans-83.9-26.9-179.9-72.6164.2000113S329 Y330 T614 S615 V618S329-L333 WeakPolarHBondContact O-CD1 3.45Å; S329-L333 WeakPolarHBondContact O-CG 3.34Å; Y330-L333 PolarHBondContact O-N 2.79Å; L333-T614 WeakPolarHBondContact O-CB 3.44Å; L333-T614 PolarHBondContact O-N 3.07Å; L333-T614 PolarHBondContact O-OG1 3.06Å; L333-S615 WeakPolarHBondContact CD2-OG 3.41Å; L333-V618 HydrophobicContact CD2-CB 3.99Å; L333-V618 HydrophobicContact CD2-CG1 3.94Å; L333-V618 HydrophobicContact CD2-CG2 3.91Å; L333-V618 HydrophobicContact CG-CG2 4.3Å
334F89.4Confident92.8Very high2 Ų218.8 Ų18.81%0.00911%0.109CC..SBendtrans-137.279.4-172.8-56.8-74.2000109.5Y183 Y330 N331 P338 W340 F438 I613Y183-F334 AromaticContact CE1-CE2 3.99Å; Y183-F334 HydrophobicContact CE1-CE2 3.99Å; Y183-F334 HydrophobicContact CE2-CE2 4.39Å; Y183-F334 HydrophobicContact CE2-CZ 4.48Å; Y183-F334 AromaticContact CZ-CE2 3.78Å; Y183-F334 AromaticContact CZ-CZ 3.98Å; Y330-F334 HydrophobicContact CD1-CB 4.04Å; Y330-F334 HydrophobicContact CD1-CD2 4.01Å; Y330-F334 HydrophobicContact CD1-CG 4.48Å; Y330-F334 AromaticContact CD2-CD2 3.62Å; Y330-F334 HydrophobicContact CD2-CD2 3.62Å; Y330-F334 AromaticContact CD2-CE2 3.97Å; Y330-F334 HydrophobicContact CD2-CE2 3.97Å; Y330-F334 HydrophobicContact CE1-CB 3.57Å; Y330-F334 AromaticContact CE1-CD2 3.82Å; Y330-F334 HydrophobicContact CE1-CD2 3.82Å; Y330-F334 AromaticContact CE1-CG 4Å; Y330-F334 HydrophobicContact CE1-CG 4Å; Y330-F334 AromaticContact CE2-CD2 3.42Å; Y330-F334 HydrophobicContact CE2-CD2 3.42Å; Y330-F334 VanDerWaalsContact CE2-CD2 3.42Å; Y330-F334 AromaticContact CE2-CE2 3.74Å; Y330-F334 HydrophobicContact CE2-CE2 3.74Å; Y330-F334 HydrophobicContact CE2-CG 4.2Å; Y330-F334 AromaticContact CG-CD2 3.9Å; Y330-F334 HydrophobicContact CG-CD2 3.9Å; Y330-F334 AromaticContact CZ-CD2 3.52Å; Y330-F334 AromaticContact CZ-CG 3.84Å; Y330-F334 PolarHBondContact O-N 2.71Å; N331-F334 CarbonylContact O-C 3.14Å; F334-P338 HydrophobicContact CB-CG 4.06Å; F334-P338 WeakPolarHBondContact O-CD 3.43Å; F334-W340 HydrophobicContact CB-CH2 3.93Å; F334-W340 AromaticContact CD1-CH2 3.47Å; F334-W340 HydrophobicContact CD1-CH2 3.47Å; F334-W340 VanDerWaalsContact CD1-CH2 3.47Å; F334-W340 HydrophobicContact CD1-CZ2 4.06Å; F334-W340 HydrophobicContact CD1-CZ3 4.47Å; F334-W340 HydrophobicContact CE1-CH2 4.32Å; F334-W340 AromaticContact CG-CH2 3.98Å; F334-W340 HydrophobicContact CG-CH2 3.98Å; F334-F438 HydrophobicContact CZ-CE1 4.43Å; F334-I613 HydrophobicContact CD1-CB 4.24Å; F334-I613 HydrophobicContact CD1-CG1 4.32Å; F334-I613 HydrophobicContact CD1-CG2 3.8Å; F334-I613 HydrophobicContact CE1-CG1 4.4Å
335S85.5Confident92.9Very high7 Ų718.5 Ų18.55%0.04911%0.107CC..  trans-78.1152.7-17257.60000114.1N331 P338 T614 Y739 V741 Q750N331-S335 WeakPolarHBondContact O-CA 3.27Å; S335-P338 WeakPolarHBondContact O-CD 3.41Å; S335-T614 WeakPolarHBondContact CB-OG1 3.4Å; S335-T614 PolarHBondContact N-OG1 3.34Å; S335-T614 WeakPolarHBondContact OG-CG2 3.19Å; S335-T614 PolarHBondContact OG-OG1 2.84Å; S335-Y739 WeakPolarHBondContact O-CE2 3.46Å; S335-Y739 PolarHBondContact O-OH 2.89Å; S335-Y739 PolarHBondContact OG-OH 2.56Å; S335-V741 WeakPolarHBondContact O-CG1 3.43Å; S335-Q750 VanDerWaalsContact CB-NE2 3.29Å; S335-Q750 VanDerWaalsContact CB-OE1 3.29Å
336G87.5Confident93.1Very high12 Ų1217.5 Ų17.512%0.12410%0.099CC..SBendtrans82.526.4174.600000114.7
337D91.4Very high93.3Very high40 Ų4017 Ų1721%0.21410%0.097CC..  trans50.648.6179.3-16138.6000114.9R118 K323R118-D337 IonicContact CZ-OD1 3.29Å; R118-D337 IonicContact CZ-OD2 3.04Å; R118-D337 IonicContact NH1-OD1 3.57Å; R118-D337 PolarHBondContact NH1-OD1 2.83Å; R118-D337 IonicContact NH1-OD2 3.96Å; R118-D337 VanDerWaalsContact NH2-CG 3.3Å; R118-D337 IonicContact NH2-OD1 2.75Å; R118-D337 PolarHBondContact NH2-OD1 3.24Å; R118-D337 IonicContact NH2-OD2 3.18Å; R118-D337 PolarHBondContact NH2-OD2 3.34Å; K323-D337 WeakPolarHBondContact CD-OD2 3.31Å; K323-D337 IonicContact NZ-OD2 3.81Å; K323-D337 PolarHBondContact NZ-OD2 2.77Å
338P94.7Very high93.6Very high7 Ų716.9 Ų16.95%0.04510%0.097CC..  trans-73.7148.8-171.731-36000113.3F334 S335 W340 Y739F334-P338 HydrophobicContact CB-CG 4.06Å; F334-P338 WeakPolarHBondContact O-CD 3.43Å; S335-P338 WeakPolarHBondContact O-CD 3.41Å; P338-W340 HydrophobicContact CB-CD2 4.06Å; P338-W340 HydrophobicContact CB-CE3 3.91Å; P338-W340 HydrophobicContact CB-CH2 3.62Å; P338-W340 HydrophobicContact CB-CZ2 3.72Å; P338-W340 HydrophobicContact CB-CZ3 3.7Å; P338-W340 HydrophobicContact CG-CE3 4.29Å; P338-W340 HydrophobicContact CG-CH2 3.23Å; P338-W340 HydrophobicContact CG-CZ2 3.68Å; P338-W340 HydrophobicContact CG-CZ3 3.57Å; P338-Y739 HydrophobicContact CB-CD2 3.78Å; P338-Y739 HydrophobicContact CB-CE2 3.6Å; P338-Y739 HydrophobicContact CG-CE2 4.02Å
339V96.2Very high94Very high4 Ų414.8 Ų14.82%0.0248%0.084CC..  trans-115.9-31.2174.3176.60000110.9A280 M281 V322 F324 A341 E375A280-V339 WeakPolarHBondContact CA-O 3.39Å; M281-V339 HydrophobicContact CB-CG1 4.41Å; M281-V339 PolarHBondContact N-O 3.34Å; V322-V339 HydrophobicContact CB-CG1 3.91Å; V322-V339 HydrophobicContact CB-CG2 4.09Å; V322-V339 HydrophobicContact CG1-CB 4.46Å; V322-V339 HydrophobicContact CG1-CG1 3.52Å; V322-V339 HydrophobicContact CG1-CG2 4.05Å; V322-V339 VanDerWaalsContact O-CG2 3.27Å; V322-V339 WeakPolarHBondContact O-CG2 3.11Å; F324-V339 HydrophobicContact CE2-CG1 4.34Å; V339-A341 HydrophobicContact CG1-CB 4.15Å; V339-E375 HydrophobicContact CB-CG 4.44Å; V339-E375 PolarHBondContact N-OE1 2.74Å
340W97.6Very high94.4Very high1 Ų117 Ų170%0.0049%0.089CC..  trans50.856.8-166.9-56.1-91.6000111.2A279 A280 M281 S282 F334 P338 T342 E375 C425 I613 Y739A279-W340 WeakPolarHBondContact O-CZ3 3.48Å; A280-W340 HydrophobicContact CB-CB 3.68Å; A280-W340 HydrophobicContact CB-CD2 4.16Å; A280-W340 HydrophobicContact CB-CE3 4.07Å; A280-W340 HydrophobicContact CB-CG 4.05Å; M281-W340 CarbonylContact C-O 3.52Å; M281-W340 VanDerWaalsContact C-O 3.32Å; S282-W340 WeakPolarHBondContact CA-O 3.49Å; S282-W340 PolarHBondContact N-O 3.36Å; S282-W340 PolarHBondContact OG-O 2.99Å; F334-W340 HydrophobicContact CB-CH2 3.93Å; F334-W340 AromaticContact CD1-CH2 3.47Å; F334-W340 HydrophobicContact CD1-CH2 3.47Å; F334-W340 VanDerWaalsContact CD1-CH2 3.47Å; F334-W340 HydrophobicContact CD1-CZ2 4.06Å; F334-W340 HydrophobicContact CD1-CZ3 4.47Å; F334-W340 HydrophobicContact CE1-CH2 4.32Å; F334-W340 AromaticContact CG-CH2 3.98Å; F334-W340 HydrophobicContact CG-CH2 3.98Å; P338-W340 HydrophobicContact CB-CD2 4.06Å; P338-W340 HydrophobicContact CB-CE3 3.91Å; P338-W340 HydrophobicContact CB-CH2 3.62Å; P338-W340 HydrophobicContact CB-CZ2 3.72Å; P338-W340 HydrophobicContact CB-CZ3 3.7Å; P338-W340 HydrophobicContact CG-CE3 4.29Å; P338-W340 HydrophobicContact CG-CH2 3.23Å; P338-W340 HydrophobicContact CG-CZ2 3.68Å; P338-W340 HydrophobicContact CG-CZ3 3.57Å; W340-T342 PolarHBondContact O-N 3.07Å; W340-T342 PolarHBondContact O-OG1 2.93Å; W340-E375 PolarHBondContact N-OE1 2.82Å; W340-C425 VanDerWaalsContact CD1-SG 3.55Å; W340-C425 PolarHBondContact NE1-SG 3.27Å; W340-I613 HydrophobicContact CZ2-CD1 3.89Å; W340-I613 HydrophobicContact CZ2-CG1 4.23Å; W340-I613 HydrophobicContact CZ2-CG2 4.03Å; W340-Y739 HydrophobicContact CZ2-CD1 4.42Å; W340-Y739 HydrophobicContact CZ2-CE1 4.46Å; W340-Y739 HydrophobicContact CZ2-CG 4.48Å; W340-Y739 VanDerWaalsContact NE1-CB 3.33Å; W340-Y739 AromaticContact NE1-CD1 3.72Å; W340-Y739 AromaticContact NE1-CG 3.43Å
341A98.3Very high94.7Very high0 Ų020.7 Ų20.70%011%0.109CC..  trans-72.452.2168.400000109.8M281 L319 V339 L343 E375 P376 N377M281-A341 WeakPolarHBondContact O-CA 3.47Å; L319-A341 HydrophobicContact CB-CB 4.46Å; V339-A341 HydrophobicContact CG1-CB 4.15Å; A341-L343 PolarHBondContact O-N 2.95Å; A341-E375 PolarHBondContact N-OE2 2.85Å; A341-P376 HydrophobicContact CB-CB 4.34Å; A341-P376 WeakPolarHBondContact O-CA 3.47Å; A341-P376 WeakPolarHBondContact O-CB 2.98Å; A341-N377 PolarHBondContact O-N 3.35Å
342T98.8Very high95.1Very high0 Ų020.4 Ų20.40%012%0.118CC..  trans-63.9125.9-168.4-50.10000110.3S282 I283 G284 W340 N377 T379 I422 C424S282-T342 WeakPolarHBondContact OG-CB 3.31Å; S282-T342 PolarHBondContact OG-OG1 3.24Å; I283-T342 WeakPolarHBondContact CG2-O 3.48Å; I283-T342 PolarHBondContact N-O 3.31Å; I283-T342 VanDerWaalsContact N-O 3.16Å; G284-T342 PolarHBondContact N-O 3.5Å; W340-T342 PolarHBondContact O-N 3.07Å; W340-T342 PolarHBondContact O-OG1 2.93Å; T342-N377 WeakPolarHBondContact CA-O 2.94Å; T342-N377 HydrophobicContact CG2-CB 4.4Å; T342-N377 WeakPolarHBondContact CG2-O 3.47Å; T342-N377 PolarHBondContact OG1-ND2 2.92Å; T342-T379 WeakPolarHBondContact CG2-OG1 3.41Å; T342-I422 HydrophobicContact CG2-CB 4.05Å; T342-I422 HydrophobicContact CG2-CG2 3.97Å; T342-I422 WeakPolarHBondContact CG2-O 3.33Å; T342-C424 PolarHBondContact OG1-O 3.05Å
343L98.8Very high95.7Very high0 Ų019.7 Ų19.70%011%0.11CC..EExtended strand (participates in β ladder)trans-122.4109.5-177.2-165161.1000108.1I283 G284 V286 L319 A341 I345 F363 P376 N377 L378 T379I283-L343 HydrophobicContact CG2-CB 3.67Å; I283-L343 HydrophobicContact CG2-CD1 3.92Å; I283-L343 HydrophobicContact CG2-CG 3.8Å; G284-L343 WeakPolarHBondContact O-CA 3.49Å; V286-L343 HydrophobicContact CG2-CD1 3.82Å; V286-L343 HydrophobicContact CG2-CD2 4.46Å; V286-L343 HydrophobicContact CG2-CG 4.01Å; L319-L343 HydrophobicContact CD1-CD1 4.35Å; A341-L343 PolarHBondContact O-N 2.95Å; L343-I345 HydrophobicContact CD2-CG2 3.26Å; L343-F363 HydrophobicContact CD1-CD1 3.64Å; L343-F363 HydrophobicContact CD1-CE1 3.25Å; L343-F363 HydrophobicContact CD1-CG 4.45Å; L343-F363 HydrophobicContact CD1-CZ 3.8Å; L343-F363 HydrophobicContact CD2-CD1 4.29Å; L343-F363 HydrophobicContact CD2-CE1 4.45Å; L343-F363 HydrophobicContact CD2-CG 4.35Å; L343-P376 HydrophobicContact CB-CB 4.25Å; L343-N377 PolarHBondContact N-O 2.85Å; L343-N377 VanDerWaalsContact N-O 3.16Å; L343-L378 HydrophobicContact CB-CD2 4.32Å; L343-L378 HydrophobicContact CD2-CD2 4.33Å; L343-T379 PolarHBondContact O-N 3.4Å
344S98.9Very high96.3Very high0 Ų019.2 Ų19.20%011%0.108CC..EExtended strand (participates in β ladder)trans-80.6127.9177.7-57.30000110.1G284 T379 I422G284-S344 PolarHBondContact O-N 3.03Å; G284-S344 VanDerWaalsContact O-N 3.09Å; S344-T379 WeakPolarHBondContact CA-O 3.43Å; S344-I422 PolarHBondContact OG-N 2.76Å
345I98.9Very high96.7Very high0 Ų019.3 Ų19.30%011%0.109CC..EExtended strand (participates in β ladder)trans-122.9161.6179.361.3177.2000111L343 D360 F363 L364 T379 V380 L381 F390L343-I345 HydrophobicContact CD2-CG2 3.26Å; I345-D360 WeakPolarHBondContact CA-OD1 3.44Å; I345-D360 HydrophobicContact CB-CB 4.34Å; I345-D360 VanDerWaalsContact CB-OD1 3.31Å; I345-D360 WeakPolarHBondContact CB-OD1 3.43Å; I345-F363 HydrophobicContact CG2-CB 4.38Å; I345-L364 HydrophobicContact CD1-CD1 4.21Å; I345-L364 HydrophobicContact CD1-CD2 3.68Å; I345-L364 HydrophobicContact CD1-CG 3.71Å; I345-T379 PolarHBondContact N-O 2.65Å; I345-V380 HydrophobicContact CD1-CG2 3.89Å; I345-V380 HydrophobicContact CG1-CG2 4.04Å; I345-L381 WeakPolarHBondContact O-CB 3.44Å; I345-L381 PolarHBondContact O-N 3.21Å; I345-F390 HydrophobicContact CD1-CZ 4.2Å; I345-F390 HydrophobicContact CG1-CZ 4.49Å
346A98.8Very high97.4Very high0 Ų019 Ų190%011%0.106CC..EExtended strand (participates in β ladder)trans62.9-134.4177.400000114.9R285 L355 V356 D360 L386 F390R285-A346 PolarHBondContact NH2-O 2.82Å; A346-L355 WeakPolarHBondContact O-CB 3.49Å; A346-V356 HydrophobicContact CB-CG2 3.55Å; A346-D360 PolarHBondContact N-OD1 3.39Å; A346-L386 HydrophobicContact CB-CD2 4.16Å; A346-F390 HydrophobicContact CB-CD1 4.1Å; A346-F390 HydrophobicContact CB-CE1 3.32Å; A346-F390 HydrophobicContact CB-CZ 3.6Å
347G98.8Very high97.9Very high0 Ų018.4 Ų18.40%010%0.1CC..  trans80.2-176.9-171.200000114.2T354 L355 L381 D409G347-T354 PolarHBondContact O-OG1 2.97Å; G347-L355 PolarHBondContact O-N 2.95Å; G347-L381 VanDerWaalsContact CA-O 3.25Å; G347-L381 WeakPolarHBondContact CA-O 3.43Å; G347-L381 PolarHBondContact N-O 3.17Å; G347-D409 WeakPolarHBondContact CA-OD2 3.28Å
348M98.8Very high98.3Very high8 Ų818.6 Ų18.64%0.03910%0.099CC..BIsolated β-bridgetrans-121.4154175.4-43.1-68.8-7100111.1R385 L386 D409 R413M348-R385 HydrophobicContact CE-CB 3.97Å; M348-R385 WeakPolarHBondContact CE-O 3.46Å; M348-R385 HydrophobicContact SD-CB 4.49Å; M348-L386 HydrophobicContact SD-CD2 3.8Å; M348-L386 HydrophobicContact SD-CG 4.43Å; M348-D409 PolarHBondContact N-OD2 3.02Å; M348-R413 VanDerWaalsContact CB-NH1 3.3Å; M348-R413 WeakPolarHBondContact O-CD 3.37Å
349G98.5Very high98.5Very high3 Ų318.3 Ų18.33%0.03110%0.097CC..  trans-77.8157.5171.100000112.3D351 G352 R353G349-D351 PolarHBondContact O-N 3.26Å; G349-G352 PolarHBondContact O-N 3.28Å; G349-R353 PolarHBondContact N-O 3.32Å
350M97.7Very high98.6Very high97 Ų9718.1 Ų18.148%0.47810%0.096SC..THydrogen-bonded Turntrans-63.3-16.8170-68.3-60.2-71.400112.6G352 R413 L417 D418M350-G352 VanDerWaalsContact C-N 3.34Å; M350-R413 HydrophobicContact SD-CG 3.62Å; M350-L417 HydrophobicContact CE-CD2 4.33Å; M350-D418 WeakPolarHBondContact CB-OD2 3.26Å; M350-D418 HydrophobicContact CG-CB 3.94Å; M350-D418 VanDerWaalsContact CG-OD2 3.26Å; M350-D418 WeakPolarHBondContact CG-OD2 3.37Å; M350-D418 PolarHBondContact N-OD2 3.24Å
351D97.8Very high98.7Very high83 Ų8318 Ų1844%0.44410%0.096SC..THydrogen-bonded Turntrans-86.8-1.217669.42.8000113.9G349 R353G349-D351 PolarHBondContact O-N 3.26Å; D351-R353 WeakPolarHBondContact OD1-CB 3.5Å; D351-R353 PolarHBondContact OD1-N 3.11Å; D351-R353 IonicContact OD1-NE 3.31Å; D351-R353 IonicContact OD2-CZ 2.82Å; D351-R353 IonicContact OD2-NE 3.73Å; D351-R353 PolarHBondContact OD2-NE 3.43Å; D351-R353 IonicContact OD2-NH2 3.29Å; D351-R353 PolarHBondContact OD2-NH2 3.21Å
352G97.7Very high98.7Very high41 Ų4118 Ų1842%0.42310%0.096SC..SBendtrans89.8-9.6178.300000115.4G349 M350G349-G352 PolarHBondContact O-N 3.28Å; M350-G352 VanDerWaalsContact C-N 3.34Å
353R98.6Very high98.7Very high94 Ų9418 Ų1836%0.35510%0.096SC..  trans-72.6150.5172.5-65-177-66.9156.90.1110Q38 Y41 P43 G349 D351Q38-R353 PolarHBondContact O-NH2 3.07Å; Q38-R353 VanDerWaalsContact O-NH2 3.16Å; Y41-R353 VanDerWaalsContact OH-CB 3.26Å; Y41-R353 WeakPolarHBondContact OH-CB 3.49Å; P43-R353 HydrophobicContact CG-CB 4.43Å; G349-R353 PolarHBondContact N-O 3.32Å; D351-R353 WeakPolarHBondContact OD1-CB 3.5Å; D351-R353 PolarHBondContact OD1-N 3.11Å; D351-R353 IonicContact OD1-NE 3.31Å; D351-R353 IonicContact OD2-CZ 2.82Å; D351-R353 IonicContact OD2-NE 3.73Å; D351-R353 PolarHBondContact OD2-NE 3.43Å; D351-R353 IonicContact OD2-NH2 3.29Å; D351-R353 PolarHBondContact OD2-NH2 3.21Å
354T98.9Very high98.7Very high5 Ų518 Ų183%0.03110%0.096CC..BIsolated β-bridgetrans-65.5148.6167.5-171.90000110.4Y41 P43 E45 G347 V356 P387Y41-T354 WeakPolarHBondContact CE2-O 3.42Å; Y41-T354 PolarHBondContact OH-O 3.49Å; P43-T354 HydrophobicContact CB-CG2 3.94Å; E45-T354 HydrophobicContact CG-CG2 4.48Å; G347-T354 PolarHBondContact O-OG1 2.97Å; T354-V356 VanDerWaalsContact C-N 3.35Å; T354-V356 HydrophobicContact CG2-CB 4.07Å; T354-V356 VanDerWaalsContact OG1-CB 3.3Å; T354-V356 WeakPolarHBondContact OG1-CB 3.5Å; T354-V356 VanDerWaalsContact OG1-CG2 3.26Å; T354-V356 WeakPolarHBondContact OG1-CG2 3.28Å; T354-V356 PolarHBondContact OG1-N 3.39Å; T354-P387 HydrophobicContact CG2-CG 3.8Å
355L98.9Very high98.7Very high4 Ų418.7 Ų18.72%0.02110%0.099CC..  trans-93.62.3165.8-78.8167.1000112.1I37 Y41 T288 A346 G347 T357 D418I37-L355 HydrophobicContact CG2-CD2 4.19Å; Y41-L355 HydrophobicContact CD1-CD2 4.33Å; Y41-L355 HydrophobicContact CD2-CD2 4.24Å; Y41-L355 HydrophobicContact CE1-CD2 3.94Å; Y41-L355 HydrophobicContact CE2-CD2 3.87Å; Y41-L355 HydrophobicContact CG-CD2 4.44Å; T288-L355 HydrophobicContact CG2-CD2 4.06Å; T288-L355 PolarHBondContact OG1-O 3.28Å; A346-L355 WeakPolarHBondContact O-CB 3.49Å; G347-L355 PolarHBondContact O-N 2.95Å; L355-T357 PolarHBondContact O-N 2.83Å; L355-D418 HydrophobicContact CD1-CB 4.12Å; L355-D418 VanDerWaalsContact CD1-O 3.32Å; L355-D418 WeakPolarHBondContact CD1-O 3.38Å
356V98.9Very high98.7Very high0 Ų018.7 Ų18.70%010%0.099CC..  trans-60.7132.6168.6175.20000109.9P43 Y44 A346 T354 D360 F361 L386 P387 F390P43-V356 WeakPolarHBondContact CA-O 3.31Å; Y44-V356 PolarHBondContact N-O 3.34Å; Y44-V356 WeakPolarHBondContact O-CG1 3.49Å; A346-V356 HydrophobicContact CB-CG2 3.55Å; T354-V356 VanDerWaalsContact C-N 3.35Å; T354-V356 HydrophobicContact CG2-CB 4.07Å; T354-V356 VanDerWaalsContact OG1-CB 3.3Å; T354-V356 WeakPolarHBondContact OG1-CB 3.5Å; T354-V356 VanDerWaalsContact OG1-CG2 3.26Å; T354-V356 WeakPolarHBondContact OG1-CG2 3.28Å; T354-V356 PolarHBondContact OG1-N 3.39Å; V356-D360 WeakPolarHBondContact CA-OD2 3.47Å; V356-F361 HydrophobicContact CG1-CD2 4.5Å; V356-F361 HydrophobicContact CG1-CE2 3.93Å; V356-L386 HydrophobicContact CG2-CD2 3.66Å; V356-P387 HydrophobicContact CB-CG 4.35Å; V356-F390 HydrophobicContact CG1-CB 3.99Å; V356-F390 HydrophobicContact CG1-CD2 3.9Å; V356-F390 HydrophobicContact CG1-CG 3.88Å; V356-F390 HydrophobicContact CG2-CB 4.39Å; V356-F390 HydrophobicContact CG2-CD1 3.83Å; V356-F390 HydrophobicContact CG2-CD2 4.45Å; V356-F390 HydrophobicContact CG2-CE1 4.26Å; V356-F390 HydrophobicContact CG2-CG 3.94Å
357T98.9Very high98.7Very high0 Ų019 Ų190%010%0.1CC..  trans-131.6171.2176.459.30000109.5Y41 T288 D291 L355 N359 D360Y41-T357 HydrophobicContact CD2-CG2 4.05Å; T288-T357 HydrophobicContact CG2-CG2 3.71Å; D291-T357 HydrophobicContact CB-CG2 4.07Å; D291-T357 WeakPolarHBondContact OD2-CB 3.32Å; L355-T357 PolarHBondContact O-N 2.83Å; T357-N359 PolarHBondContact O-N 3.12Å; T357-N359 PolarHBondContact OG1-N 2.94Å; T357-D360 PolarHBondContact N-OD2 3.29Å; T357-D360 PolarHBondContact O-N 3.36Å; T357-D360 PolarHBondContact OG1-OD2 3.28Å
358K98.9Very high98.6Very high44 Ų4422.4 Ų22.419%0.19112%0.116CC..Hα-helixtrans-57.1-33.4171.6-75.6-170166.3-164.40112.1Y44 F50 D360 F361 R362Y44-K358 HydrophobicContact CD1-CG 4.02Å; Y44-K358 HydrophobicContact CD2-CD 4.49Å; Y44-K358 HydrophobicContact CD2-CG 3.79Å; Y44-K358 HydrophobicContact CE1-CG 4.29Å; Y44-K358 HydrophobicContact CE2-CG 4.08Å; Y44-K358 HydrophobicContact CG-CG 3.76Å; F50-K358 HydrophobicContact CD2-CD 3.91Å; F50-K358 HydrophobicContact CD2-CG 4.35Å; F50-K358 HydrophobicContact CE1-CB 4.37Å; F50-K358 HydrophobicContact CE1-CD 4.5Å; F50-K358 HydrophobicContact CE1-CG 4.01Å; F50-K358 HydrophobicContact CE2-CB 3.67Å; F50-K358 HydrophobicContact CE2-CD 3.76Å; F50-K358 HydrophobicContact CE2-CG 3.8Å; F50-K358 HydrophobicContact CG-CD 4.34Å; F50-K358 HydrophobicContact CZ-CB 3.52Å; F50-K358 HydrophobicContact CZ-CD 4.07Å; F50-K358 HydrophobicContact CZ-CG 3.6Å; F50-K358 WeakPolarHBondContact CZ-O 3.42Å; K358-D360 VanDerWaalsContact C-N 3.27Å; K358-D360 PolarHBondContact O-N 3Å; K358-F361 WeakPolarHBondContact O-CB 3.29Å; K358-F361 PolarHBondContact O-N 2.73Å; K358-R362 WeakPolarHBondContact O-CG 3.24Å; K358-R362 PolarHBondContact O-N 2.77Å
359N98.9Very high98.6Very high0 Ų022.8 Ų22.80%012%0.118CC..Hα-helixtrans-66.4-28.6-178.9-140.236.8000113.6S287 D291 I294 I312 T357 F361 R362 F363S287-N359 PolarHBondContact O-ND2 3.04Å; D291-N359 HydrophobicContact CB-CB 3.64Å; D291-N359 WeakPolarHBondContact OD1-CB 3.37Å; D291-N359 PolarHBondContact OD1-N 3.49Å; I294-N359 WeakPolarHBondContact CD1-OD1 3.48Å; I312-N359 WeakPolarHBondContact CD1-OD1 3.43Å; I312-N359 WeakPolarHBondContact CG1-OD1 3.12Å; T357-N359 PolarHBondContact O-N 3.12Å; T357-N359 PolarHBondContact OG1-N 2.94Å; N359-F361 VanDerWaalsContact C-N 3.29Å; N359-F361 PolarHBondContact O-N 3.31Å; N359-R362 PolarHBondContact O-N 3.17Å; N359-R362 VanDerWaalsContact O-N 3.13Å; N359-R362 PolarHBondContact OD1-NH1 3.5Å; N359-F363 WeakPolarHBondContact ND2-CE2 3.32Å; N359-F363 VanDerWaalsContact O-CD2 3.25Å; N359-F363 WeakPolarHBondContact O-CD2 3.3Å; N359-F363 PolarHBondContact O-N 3.42Å
360D98.9Very high98.6Very high0 Ų022.7 Ų22.70%012%0.117CC..Hα-helixtrans-64-37.9175.3-59.9-68.1000111.1S287 I345 A346 V356 T357 K358 L364 F390S287-D360 VanDerWaalsContact CB-OD1 3.24Å; S287-D360 WeakPolarHBondContact CB-OD1 3.45Å; S287-D360 WeakPolarHBondContact OG-CA 3.4Å; S287-D360 VanDerWaalsContact OG-CG 3.23Å; S287-D360 PolarHBondContact OG-N 3.35Å; S287-D360 PolarHBondContact OG-OD1 2.66Å; I345-D360 WeakPolarHBondContact CA-OD1 3.44Å; I345-D360 HydrophobicContact CB-CB 4.34Å; I345-D360 VanDerWaalsContact CB-OD1 3.31Å; I345-D360 WeakPolarHBondContact CB-OD1 3.43Å; A346-D360 PolarHBondContact N-OD1 3.39Å; V356-D360 WeakPolarHBondContact CA-OD2 3.47Å; T357-D360 PolarHBondContact N-OD2 3.29Å; T357-D360 PolarHBondContact O-N 3.36Å; T357-D360 PolarHBondContact OG1-OD2 3.28Å; K358-D360 VanDerWaalsContact C-N 3.27Å; K358-D360 PolarHBondContact O-N 3Å; D360-L364 WeakPolarHBondContact O-CG 3.26Å; D360-L364 PolarHBondContact O-N 3.19Å; D360-F390 HydrophobicContact CB-CD2 4.38Å; D360-F390 HydrophobicContact CB-CE2 3.63Å; D360-F390 HydrophobicContact CB-CZ 4.16Å
361F98.9Very high98.5Very high0 Ų019 Ų190%010%0.103CC..Hα-helixtrans-66.2-44.9169.4-69.7-102.4000111.4Y44 G46 A48 F50 L51 V356 K358 N359 F363 L364 H365 G389 F390 Y393Y44-F361 AromaticContact CD1-CD2 4Å; Y44-F361 HydrophobicContact CD1-CD2 4Å; Y44-F361 AromaticContact CD1-CE2 3.59Å; Y44-F361 HydrophobicContact CD1-CE2 3.59Å; Y44-F361 HydrophobicContact CD1-CZ 4.37Å; Y44-F361 HydrophobicContact CE1-CD2 4.19Å; Y44-F361 AromaticContact CE1-CE2 3.79Å; Y44-F361 HydrophobicContact CE1-CE2 3.79Å; Y44-F361 HydrophobicContact CE1-CZ 4.19Å; G46-F361 WeakPolarHBondContact O-CZ 3.05Å; A48-F361 HydrophobicContact CB-CD1 3.78Å; A48-F361 HydrophobicContact CB-CE1 3.97Å; F50-F361 HydrophobicContact CE1-CB 4.08Å; F50-F361 HydrophobicContact CE1-CD2 4.31Å; F50-F361 HydrophobicContact CE1-CG 4.08Å; F50-F361 HydrophobicContact CZ-CB 3.82Å; F50-F361 HydrophobicContact CZ-CG 4.28Å; L51-F361 HydrophobicContact CD1-CB 4.32Å; L51-F361 HydrophobicContact CD2-CB 3.97Å; L51-F361 HydrophobicContact CG-CB 4.44Å; V356-F361 HydrophobicContact CG1-CD2 4.5Å; V356-F361 HydrophobicContact CG1-CE2 3.93Å; K358-F361 WeakPolarHBondContact O-CB 3.29Å; K358-F361 PolarHBondContact O-N 2.73Å; N359-F361 VanDerWaalsContact C-N 3.29Å; N359-F361 PolarHBondContact O-N 3.31Å; F361-F363 VanDerWaalsContact C-N 3.29Å; F361-F363 PolarHBondContact O-N 3.44Å; F361-L364 PolarHBondContact O-N 3.41Å; F361-L364 VanDerWaalsContact O-N 3.15Å; F361-H365 WeakPolarHBondContact O-CB 3.41Å; F361-H365 PolarHBondContact O-N 3.49Å; F361-G389 WeakPolarHBondContact CE1-O 3.41Å; F361-F390 HydrophobicContact CD1-CD2 4.48Å; F361-F390 AromaticContact CD2-CD2 3.79Å; F361-F390 HydrophobicContact CD2-CD2 3.79Å; F361-F390 HydrophobicContact CD2-CE2 4.47Å; F361-F390 HydrophobicContact CE1-CB 4.43Å; F361-F390 HydrophobicContact CE1-CD2 4.26Å; F361-F390 HydrophobicContact CE2-CB 3.85Å; F361-F390 AromaticContact CE2-CD2 3.53Å; F361-F390 HydrophobicContact CE2-CD2 3.53Å; F361-F390 HydrophobicContact CE2-CG 4.16Å; F361-F390 HydrophobicContact CG-CD2 4.27Å; F361-F390 VanDerWaalsContact CZ-CA 3.45Å; F361-F390 HydrophobicContact CZ-CB 3.59Å; F361-F390 AromaticContact CZ-CD2 3.8Å; F361-F390 HydrophobicContact CZ-CD2 3.8Å; F361-F390 HydrophobicContact CZ-CG 4.2Å; F361-Y393 HydrophobicContact CB-CD1 4.45Å; F361-Y393 HydrophobicContact CB-CE1 4.33Å; F361-Y393 AromaticContact CD1-CD1 3.34Å; F361-Y393 HydrophobicContact CD1-CD1 3.34Å; F361-Y393 AromaticContact CD1-CE1 3.93Å; F361-Y393 HydrophobicContact CD1-CE1 3.93Å; F361-Y393 AromaticContact CD1-CG 3.87Å; F361-Y393 HydrophobicContact CD1-CG 3.87Å; F361-Y393 AromaticContact CE1-CD1 3.92Å; F361-Y393 HydrophobicContact CE1-CD1 3.92Å; F361-Y393 HydrophobicContact CE1-CG 4.05Å; F361-Y393 HydrophobicContact CG-CD1 4.22Å
362R98.9Very high98.5Very high0 Ų016.7 Ų16.70%09%0.093CC..Hα-helixtrans-57.6-40178.6-63.2-170.7-165.895.45.3112.8F50 L51 D291 E305 Q309 I312 K358 N359 H365 T366F50-R362 HydrophobicContact CE2-CG 4.41Å; L51-R362 HydrophobicContact CD2-CG 4.13Å; D291-R362 IonicContact OD1-NH1 2.62Å; D291-R362 PolarHBondContact OD1-NH1 2.75Å; E305-R362 IonicContact OE1-CZ 2.71Å; E305-R362 IonicContact OE1-NE 3.48Å; E305-R362 PolarHBondContact OE1-NE 2.79Å; E305-R362 IonicContact OE1-NH2 2.77Å; E305-R362 PolarHBondContact OE1-NH2 3.43Å; E305-R362 IonicContact OE2-CZ 2.73Å; E305-R362 IonicContact OE2-NE 2.66Å; E305-R362 IonicContact OE2-NH2 3.72Å; E305-R362 PolarHBondContact OE2-NH2 2.83Å; Q309-R362 PolarHBondContact NE2-O 3.11Å; Q309-R362 VanDerWaalsContact OE1-CG 3.25Å; I312-R362 HydrophobicContact CB-CB 4.41Å; I312-R362 HydrophobicContact CG1-CB 4.18Å; I312-R362 HydrophobicContact CG2-CB 4.26Å; K358-R362 WeakPolarHBondContact O-CG 3.24Å; K358-R362 PolarHBondContact O-N 2.77Å; N359-R362 PolarHBondContact O-N 3.17Å; N359-R362 VanDerWaalsContact O-N 3.13Å; N359-R362 PolarHBondContact OD1-NH1 3.5Å; R362-H365 PolarHBondContact O-N 3.33Å; R362-T366 WeakPolarHBondContact O-CG2 3.47Å; R362-T366 PolarHBondContact O-N 3.49Å
363F98.9Very high98.5Very high0 Ų015 Ų150%08%0.075CC..Hα-helixtrans-65.3-44.3176.2-88.9-73.8000112V286 L290 I312 L315 V316 L343 I345 N359 F361 H365 T366 L378V286-F363 HydrophobicContact CG2-CZ 4.34Å; L290-F363 HydrophobicContact CD1-CZ 4.26Å; I312-F363 HydrophobicContact CD1-CE2 3.95Å; I312-F363 HydrophobicContact CD1-CZ 4Å; I312-F363 HydrophobicContact CG2-CD1 3.78Å; I312-F363 HydrophobicContact CG2-CD2 4.14Å; I312-F363 HydrophobicContact CG2-CE1 3.85Å; I312-F363 HydrophobicContact CG2-CE2 4.19Å; I312-F363 HydrophobicContact CG2-CG 3.93Å; I312-F363 HydrophobicContact CG2-CZ 4.07Å; L315-F363 HydrophobicContact CD2-CE1 4.08Å; L315-F363 HydrophobicContact CD2-CZ 3.84Å; V316-F363 HydrophobicContact CG2-CD1 3.74Å; V316-F363 HydrophobicContact CG2-CE1 3.79Å; L343-F363 HydrophobicContact CD1-CD1 3.64Å; L343-F363 HydrophobicContact CD1-CE1 3.25Å; L343-F363 HydrophobicContact CD1-CG 4.45Å; L343-F363 HydrophobicContact CD1-CZ 3.8Å; L343-F363 HydrophobicContact CD2-CD1 4.29Å; L343-F363 HydrophobicContact CD2-CE1 4.45Å; L343-F363 HydrophobicContact CD2-CG 4.35Å; I345-F363 HydrophobicContact CG2-CB 4.38Å; N359-F363 WeakPolarHBondContact ND2-CE2 3.32Å; N359-F363 VanDerWaalsContact O-CD2 3.25Å; N359-F363 WeakPolarHBondContact O-CD2 3.3Å; N359-F363 PolarHBondContact O-N 3.42Å; F361-F363 VanDerWaalsContact C-N 3.29Å; F361-F363 PolarHBondContact O-N 3.44Å; F363-H365 VanDerWaalsContact C-N 3.33Å; F363-T366 WeakPolarHBondContact O-CB 3.27Å; F363-T366 WeakPolarHBondContact O-CG2 3.17Å; F363-T366 PolarHBondContact O-N 3.25Å; F363-T366 PolarHBondContact O-OG1 2.9Å; F363-L378 HydrophobicContact CB-CD2 4.22Å
364L98.9Very high98.5Very high0 Ų011.3 Ų11.30%06%0.063CC..Hα-helixtrans-62.4-41.3173.7-73.1177.4000111.7I345 D360 F361 T366 L367 L378 F390 Y393 A394 I397 I404I345-L364 HydrophobicContact CD1-CD1 4.21Å; I345-L364 HydrophobicContact CD1-CD2 3.68Å; I345-L364 HydrophobicContact CD1-CG 3.71Å; D360-L364 WeakPolarHBondContact O-CG 3.26Å; D360-L364 PolarHBondContact O-N 3.19Å; F361-L364 PolarHBondContact O-N 3.41Å; F361-L364 VanDerWaalsContact O-N 3.15Å; L364-T366 PolarHBondContact O-N 2.86Å; L364-T366 VanDerWaalsContact O-N 3.12Å; L364-L367 WeakPolarHBondContact O-CB 3.3Å; L364-L367 PolarHBondContact O-N 3.29Å; L364-L378 HydrophobicContact CD2-CD1 4.45Å; L364-F390 HydrophobicContact CD1-CE2 3.68Å; L364-F390 HydrophobicContact CD1-CZ 3.92Å; L364-Y393 HydrophobicContact CB-CD1 4.31Å; L364-Y393 HydrophobicContact CB-CE1 3.78Å; L364-Y393 HydrophobicContact CD1-CD1 3.99Å; L364-Y393 HydrophobicContact CD1-CE1 4.32Å; L364-A394 HydrophobicContact CD1-CB 4.1Å; L364-I397 HydrophobicContact CB-CG1 4.29Å; L364-I397 HydrophobicContact CD2-CG2 4.3Å; L364-I404 HydrophobicContact CD2-CD1 4.07Å; L364-I404 HydrophobicContact CD2-CG2 3.84Å
365H98.8Very high98.4Very high13 Ų1311.7 Ų11.76%0.067%0.065CC..Hα-helixtrans-63.1-19.4-178.9-162.553.1000113.5L51 A52 F361 R362 F363 L367 E368 N369 Y393L51-H365 HydrophobicContact CD1-CB 3.93Å; L51-H365 HydrophobicContact CD2-CB 3.96Å; L51-H365 HydrophobicContact CG-CB 4.48Å; A52-H365 PolarHBondContact O-CD2 3.4Å; A52-H365 PolarHBondContact O-NE2 2.92Å; F361-H365 WeakPolarHBondContact O-CB 3.41Å; F361-H365 PolarHBondContact O-N 3.49Å; R362-H365 PolarHBondContact O-N 3.33Å; F363-H365 VanDerWaalsContact C-N 3.33Å; H365-L367 PolarHBondContact O-N 2.86Å; H365-L367 VanDerWaalsContact O-N 3.12Å; H365-E368 IonicContact CE1-OE2 3.59Å; H365-E368 PolarHBondContact CE1-OE2 3.22Å; H365-E368 IonicContact CG-OE2 2.73Å; H365-E368 IonicContact ND1-OE2 3.94Å; H365-E368 PolarHBondContact ND1-OE2 3.4Å; H365-E368 WeakPolarHBondContact O-CA 3.46Å; H365-E368 PolarHBondContact O-N 2.68Å; H365-N369 PolarHBondContact CD2-OD1 3.33Å; H365-N369 PolarHBondContact NE2-OD1 2.89Å; H365-N369 VanDerWaalsContact NE2-OD1 3.13Å; H365-N369 PolarHBondContact O-N 2.77Å; H365-Y393 WeakPolarHBondContact CA-OH 3.39Å; H365-Y393 WeakPolarHBondContact CB-OH 3.18Å; H365-Y393 PolarHBondContact ND1-OH 3.5Å; H365-Y393 VanDerWaalsContact ND1-OH 3.07Å
366T98.9Very high98.4Very high0 Ų011.7 Ų11.70%07%0.065CC..Hα-helixtrans-60.2-21.9171.570.60000113.5I312 D313 V316 R320 R362 F363 L364 E368 M370I312-T366 HydrophobicContact CG2-CG2 3.94Å; D313-T366 WeakPolarHBondContact OD1-CG2 3.27Å; V316-T366 HydrophobicContact CB-CG2 4.03Å; V316-T366 HydrophobicContact CG1-CG2 4.21Å; V316-T366 HydrophobicContact CG2-CG2 3.79Å; R320-T366 PolarHBondContact NH2-O 2.93Å; R320-T366 VanDerWaalsContact NH2-O 3.13Å; R362-T366 WeakPolarHBondContact O-CG2 3.47Å; R362-T366 PolarHBondContact O-N 3.49Å; F363-T366 WeakPolarHBondContact O-CB 3.27Å; F363-T366 WeakPolarHBondContact O-CG2 3.17Å; F363-T366 PolarHBondContact O-N 3.25Å; F363-T366 PolarHBondContact O-OG1 2.9Å; L364-T366 PolarHBondContact O-N 2.86Å; L364-T366 VanDerWaalsContact O-N 3.12Å; T366-E368 VanDerWaalsContact C-N 3.34Å; T366-M370 HydrophobicContact CG2-CE 4.09Å; T366-M370 WeakPolarHBondContact O-CB 3.45Å; T366-M370 PolarHBondContact O-N 3.48Å; T366-M370 VanDerWaalsContact O-N 3.09Å
367L98.7Very high98.4Very high6 Ų611.7 Ų11.73%0.0317%0.065CC..Hα-helixtrans-79.2-16.4173.8-63.4170000113L364 H365 G371 L378 I397 T401 I404L364-L367 WeakPolarHBondContact O-CB 3.3Å; L364-L367 PolarHBondContact O-N 3.29Å; H365-L367 PolarHBondContact O-N 2.86Å; H365-L367 VanDerWaalsContact O-N 3.12Å; L367-G371 CarbonylContact O-C 3.52Å; L367-G371 WeakPolarHBondContact O-CA 3.49Å; L367-L378 HydrophobicContact CD1-CD1 3.8Å; L367-L378 HydrophobicContact CG-CD1 4.11Å; L367-I397 HydrophobicContact CB-CG2 4.42Å; L367-I397 HydrophobicContact CD1-CG2 3.53Å; L367-T401 HydrophobicContact CB-CG2 4.09Å; L367-I404 HydrophobicContact CD1-CG2 3.57Å
368E98.1Very high98.4Very high73 Ų7311.8 Ų11.834%0.3417%0.065SC..Hα-helixtrans-91.1-55.1168.8-68.3177.6125.300109.5H365 T366 M370 G371 Y393 K396 I397H365-E368 IonicContact CE1-OE2 3.59Å; H365-E368 PolarHBondContact CE1-OE2 3.22Å; H365-E368 IonicContact CG-OE2 2.73Å; H365-E368 IonicContact ND1-OE2 3.94Å; H365-E368 PolarHBondContact ND1-OE2 3.4Å; H365-E368 WeakPolarHBondContact O-CA 3.46Å; H365-E368 PolarHBondContact O-N 2.68Å; T366-E368 VanDerWaalsContact C-N 3.34Å; E368-M370 PolarHBondContact O-N 2.97Å; E368-G371 PolarHBondContact O-N 3.23Å; E368-Y393 PolarHBondContact OE2-OH 2.76Å; E368-K396 IonicContact OE1-NZ 3.15Å; E368-K396 PolarHBondContact OE1-NZ 3.13Å; E368-I397 HydrophobicContact CG-CD1 3.75Å
369N98.2Very high98.4Very high15 Ų159.7 Ų9.78%0.086%0.056CC..Hα-helixtrans-58.7-42-177.1-81.19.3000114.3A52 P54 Q309 D313 H365A52-N369 PolarHBondContact O-ND2 3.02Å; P54-N369 HydrophobicContact CB-CB 4.04Å; P54-N369 WeakPolarHBondContact CD-OD1 3.12Å; P54-N369 HydrophobicContact CG-CB 4.29Å; Q309-N369 WeakPolarHBondContact CG-ND2 3.35Å; D313-N369 PolarHBondContact OD2-ND2 3Å; D313-N369 VanDerWaalsContact OD2-ND2 3.11Å; H365-N369 PolarHBondContact CD2-OD1 3.33Å; H365-N369 PolarHBondContact NE2-OD1 2.89Å; H365-N369 VanDerWaalsContact NE2-OD1 3.13Å; H365-N369 PolarHBondContact O-N 2.77Å
370M97.8Very high98.4Very high2 Ų29.7 Ų9.71%0.016%0.056CC..THydrogen-bonded Turntrans-115.812.9-178.8-62.1-179.9-71.400112T58 W62 D313 V316 M317 R320 T366 E368T58-M370 HydrophobicContact CG2-CG 4Å; T58-M370 HydrophobicContact CG2-SD 4.21Å; W62-M370 HydrophobicContact CB-CG 4.45Å; W62-M370 HydrophobicContact CD2-CB 3.92Å; W62-M370 HydrophobicContact CD2-CG 4.22Å; W62-M370 HydrophobicContact CD2-SD 4.44Å; W62-M370 HydrophobicContact CE3-CB 4.41Å; W62-M370 HydrophobicContact CE3-SD 4.27Å; W62-M370 HydrophobicContact CG-CB 4.13Å; W62-M370 HydrophobicContact CG-CG 4.12Å; W62-M370 HydrophobicContact CZ2-CB 4.34Å; W62-M370 WeakPolarHBondContact CZ2-O 3.48Å; W62-M370 PolarHBondContact NE1-O 3.2Å; D313-M370 HydrophobicContact CB-CE 3.89Å; D313-M370 HydrophobicContact CB-SD 4.14Å; D313-M370 VanDerWaalsContact O-CE 3.31Å; D313-M370 WeakPolarHBondContact O-CE 3.02Å; V316-M370 HydrophobicContact CB-CE 4.02Å; V316-M370 HydrophobicContact CG1-CE 3.75Å; M317-M370 HydrophobicContact CB-SD 4.16Å; M317-M370 HydrophobicContact CE-SD 3.65Å; R320-M370 VanDerWaalsContact NH1-CB 3.34Å; R320-M370 PolarHBondContact NH1-O 3.44Å; T366-M370 HydrophobicContact CG2-CE 4.09Å; T366-M370 WeakPolarHBondContact O-CB 3.45Å; T366-M370 PolarHBondContact O-N 3.48Å; T366-M370 VanDerWaalsContact O-N 3.09Å; E368-M370 PolarHBondContact O-N 2.97Å
371G96.8Very high98.4Very high18 Ų189.7 Ų9.719%0.1866%0.056CC..  trans67.6174-176.800000115.1R320 L367 E368R320-G371 PolarHBondContact NH1-O 3.13Å; R320-G371 PolarHBondContact NH2-O 2.85Å; R320-G371 VanDerWaalsContact NH2-O 3.1Å; L367-G371 CarbonylContact O-C 3.52Å; L367-G371 WeakPolarHBondContact O-CA 3.49Å; E368-G371 PolarHBondContact O-N 3.23Å
372P97.5Very high98.4Very high36 Ų369.7 Ų9.723%0.2346%0.056CC..  trans-58.4145.2-178.1-2433.6000112.4T401P372-T401 HydrophobicContact CG-CG2 4.11Å
373S97.5Very high98.4Very high5 Ų59.7 Ų9.74%0.0356%0.056CC..  trans-156.5145.4178.6-1580000111.2R320 E375R320-S373 VanDerWaalsContact NE-CB 3.32Å; R320-S373 PolarHBondContact NE-OG 3.06Å; S373-E375 VanDerWaalsContact C-N 3.29Å; S373-E375 PolarHBondContact O-N 3.44Å; S373-E375 PolarHBondContact OG-O 3.47Å
374P97.4Very high98.3Very high16 Ų1611.3 Ų11.310%0.1047%0.067CC..SBendtrans-70.8-26.2176.327.7-36.1000114T733 A740 K742P374-T733 HydrophobicContact CB-CG2 4.26Å; P374-A740 VanDerWaalsContact CB-C 3.4Å; P374-A740 HydrophobicContact CB-CB 3.79Å; P374-A740 WeakPolarHBondContact CB-O 3Å; P374-K742 HydrophobicContact CG-CG 4.17Å
375E98Very high98.3Very high14 Ų1417.4 Ų17.47%0.0659%0.09CC..  trans-122.5148.9-178-61.9-68.7-179.200110.6R320 V339 W340 A341 S373 N377R320-E375 WeakPolarHBondContact CG-O 3.19Å; R320-E375 PolarHBondContact NE-O 2.91Å; V339-E375 HydrophobicContact CB-CG 4.44Å; V339-E375 PolarHBondContact N-OE1 2.74Å; W340-E375 PolarHBondContact N-OE1 2.82Å; A341-E375 PolarHBondContact N-OE2 2.85Å; S373-E375 VanDerWaalsContact C-N 3.29Å; S373-E375 PolarHBondContact O-N 3.44Å; S373-E375 PolarHBondContact OG-O 3.47Å; E375-N377 PolarHBondContact OE2-N 3.49Å; E375-N377 VanDerWaalsContact OE2-N 3.17Å
376P98.5Very high98.3Very high4 Ų417.1 Ų17.13%0.0269%0.089CC..SBendcis-59.7148-1328.8-35000111V316 L319 A341 L343 L378V316-P376 HydrophobicContact CG1-CG 4.3Å; V316-P376 HydrophobicContact CG2-CG 4.21Å; L319-P376 HydrophobicContact CB-CB 4.29Å; L319-P376 HydrophobicContact CD1-CB 3.88Å; L319-P376 HydrophobicContact CD1-CG 4.07Å; A341-P376 HydrophobicContact CB-CB 4.34Å; A341-P376 WeakPolarHBondContact O-CA 3.47Å; A341-P376 WeakPolarHBondContact O-CB 2.98Å; L343-P376 HydrophobicContact CB-CB 4.25Å; P376-L378 HydrophobicContact CG-CD2 4.22Å; P376-L378 HydrophobicContact CG-CG 4.26Å; P376-L378 PolarHBondContact O-N 3.29Å
377N98.6Very high98.3Very high0 Ų017.9 Ų17.90%09%0.094CC..  trans-6884.4174.4-177.733.2000110.3A341 T342 L343 E375 T379 Q405 C424 R735 G738A341-N377 PolarHBondContact O-N 3.35Å; T342-N377 WeakPolarHBondContact CA-O 2.94Å; T342-N377 HydrophobicContact CG2-CB 4.4Å; T342-N377 WeakPolarHBondContact CG2-O 3.47Å; T342-N377 PolarHBondContact OG1-ND2 2.92Å; L343-N377 PolarHBondContact N-O 2.85Å; L343-N377 VanDerWaalsContact N-O 3.16Å; E375-N377 PolarHBondContact OE2-N 3.49Å; E375-N377 VanDerWaalsContact OE2-N 3.17Å; N377-T379 PolarHBondContact O-N 2.75Å; N377-T379 PolarHBondContact O-OG1 3.29Å; N377-Q405 PolarHBondContact ND2-NE2 3.28Å; N377-C424 PolarHBondContact ND2-O 3.21Å; N377-R735 VanDerWaalsContact OD1-CZ 3.26Å; N377-R735 PolarHBondContact OD1-NH1 2.91Å; N377-R735 PolarHBondContact OD1-NH2 2.79Å; N377-G738 PolarHBondContact ND2-O 3.24Å
378L98.7Very high98.3Very high1 Ų122.4 Ų22.41%0.00512%0.115CC..EExtended strand (participates in β ladder)trans-67.1120.8-176.9-72.4170.3000110.3L343 F363 L364 L367 P376 I404 Q405L343-L378 HydrophobicContact CB-CD2 4.32Å; L343-L378 HydrophobicContact CD2-CD2 4.33Å; F363-L378 HydrophobicContact CB-CD2 4.22Å; L364-L378 HydrophobicContact CD2-CD1 4.45Å; L367-L378 HydrophobicContact CD1-CD1 3.8Å; L367-L378 HydrophobicContact CG-CD1 4.11Å; P376-L378 HydrophobicContact CG-CD2 4.22Å; P376-L378 HydrophobicContact CG-CG 4.26Å; P376-L378 PolarHBondContact O-N 3.29Å; L378-I404 HydrophobicContact CB-CB 4.49Å; L378-I404 HydrophobicContact CB-CG2 3.88Å; L378-I404 HydrophobicContact CD1-CG2 4.29Å; L378-Q405 PolarHBondContact O-N 2.98Å; L378-Q405 VanDerWaalsContact O-N 3.1Å
379T98.9Very high98.3Very high0 Ų019.8 Ų19.80%011%0.108CC..EExtended strand (participates in β ladder)trans-123.9108.8-173.6-56.50000110.3T342 L343 S344 I345 N377 L381 Q405 E407 I422T342-T379 WeakPolarHBondContact CG2-OG1 3.41Å; L343-T379 PolarHBondContact O-N 3.4Å; S344-T379 WeakPolarHBondContact CA-O 3.43Å; I345-T379 PolarHBondContact N-O 2.65Å; N377-T379 PolarHBondContact O-N 2.75Å; N377-T379 PolarHBondContact O-OG1 3.29Å; T379-L381 PolarHBondContact O-N 3.3Å; T379-Q405 WeakPolarHBondContact CA-O 3.4Å; T379-Q405 HydrophobicContact CG2-CG 3.98Å; T379-Q405 WeakPolarHBondContact OG1-CG 3.4Å; T379-Q405 PolarHBondContact OG1-NE2 3.42Å; T379-E407 HydrophobicContact CG2-CB 4.33Å; T379-E407 HydrophobicContact CG2-CG 3.76Å; T379-E407 WeakPolarHBondContact CG2-OE1 3.04Å; T379-I422 HydrophobicContact CG2-CB 4.3Å; T379-I422 HydrophobicContact CG2-CG1 3.83Å
380V98.9Very high98.3Very high0 Ų019.1 Ų19.10%010%0.104CC..EExtended strand (participates in β ladder)trans-77.9115.4176.8177.50000109I345 Y382 L386 F390 A394 I404 Q405 Y406 E407I345-V380 HydrophobicContact CD1-CG2 3.89Å; I345-V380 HydrophobicContact CG1-CG2 4.04Å; V380-Y382 HydrophobicContact CG1-CD2 4.28Å; V380-Y382 PolarHBondContact O-N 2.77Å; V380-L386 HydrophobicContact CG1-CD1 4.47Å; V380-F390 HydrophobicContact CG1-CE1 3.92Å; V380-A394 HydrophobicContact CG2-CB 4.33Å; V380-I404 HydrophobicContact CG2-CD1 4.11Å; V380-Q405 PolarHBondContact N-O 3.33Å; V380-Y406 HydrophobicContact CB-CD1 3.62Å; V380-Y406 HydrophobicContact CB-CE1 4.01Å; V380-Y406 HydrophobicContact CB-CG 4.39Å; V380-Y406 HydrophobicContact CG1-CD1 3.78Å; V380-Y406 HydrophobicContact CG1-CE1 4.1Å; V380-Y406 HydrophobicContact CG2-CD1 4.18Å; V380-Y406 HydrophobicContact CG2-CE1 4.09Å; V380-Y406 WeakPolarHBondContact O-CA 3.3Å; V380-E407 PolarHBondContact O-N 3Å
381L98.9Very high98.4Very high0 Ų019.4 Ų19.40%011%0.105CC..EExtended strand (participates in β ladder)trans-75.594.1168.7-59.4-178000108I345 G347 T379 E407 D409 M412 Y420 I422I345-L381 WeakPolarHBondContact O-CB 3.44Å; I345-L381 PolarHBondContact O-N 3.21Å; G347-L381 VanDerWaalsContact CA-O 3.25Å; G347-L381 WeakPolarHBondContact CA-O 3.43Å; G347-L381 PolarHBondContact N-O 3.17Å; T379-L381 PolarHBondContact O-N 3.3Å; L381-E407 CarbonylContact C-O 3.52Å; L381-E407 WeakPolarHBondContact CA-O 3.47Å; L381-D409 HydrophobicContact CB-CB 4.09Å; L381-M412 HydrophobicContact CD2-CE 4.1Å; L381-Y420 HydrophobicContact CD1-CE1 4.27Å; L381-Y420 HydrophobicContact CD1-CE2 4.2Å; L381-Y420 HydrophobicContact CD2-CE2 3.88Å; L381-I422 HydrophobicContact CD2-CD1 4.25Å; L381-I422 HydrophobicContact CD2-CG1 3.96Å
382Y98.9Very high98.5Very high1 Ų121.3 Ų21.30%0.00411%0.111CC..EExtended strand (participates in β ladder)trans-84.3140.3-168.4-163.8-88.3000112.1V380 L386 K391 Y406 E407 D409 T693 L696 D697 F700V380-Y382 HydrophobicContact CG1-CD2 4.28Å; V380-Y382 PolarHBondContact O-N 2.77Å; Y382-L386 HydrophobicContact CD2-CD1 4.19Å; Y382-L386 HydrophobicContact CG-CD1 4.48Å; Y382-K391 HydrophobicContact CE2-CD 4.43Å; Y382-K391 HydrophobicContact CE2-CG 4.31Å; Y382-Y406 AromaticContact CD2-CD1 3.68Å; Y382-Y406 HydrophobicContact CD2-CD1 3.68Å; Y382-Y406 HydrophobicContact CD2-CE1 4.13Å; Y382-Y406 HydrophobicContact CE2-CD1 4.39Å; Y382-Y406 HydrophobicContact CE2-CE1 4.49Å; Y382-Y406 HydrophobicContact CG-CD1 4.37Å; Y382-E407 PolarHBondContact N-O 3.06Å; Y382-D409 VanDerWaalsContact O-CB 3.28Å; Y382-D409 WeakPolarHBondContact O-CB 3.44Å; Y382-D409 PolarHBondContact O-N 2.95Å; Y382-T693 PolarHBondContact OH-O 3.49Å; Y382-L696 HydrophobicContact CE1-CB 3.96Å; Y382-L696 HydrophobicContact CE2-CB 3.86Å; Y382-L696 HydrophobicContact CE2-CD1 3.98Å; Y382-L696 HydrophobicContact CE2-CG 4.48Å; Y382-L696 VanDerWaalsContact CZ-CB 3.5Å; Y382-L696 WeakPolarHBondContact OH-CB 3.19Å; Y382-D697 VanDerWaalsContact CE1-OD1 3.29Å; Y382-D697 WeakPolarHBondContact CE1-OD1 3.44Å; Y382-D697 VanDerWaalsContact CZ-OD1 3.28Å; Y382-D697 PolarHBondContact OH-OD1 3.45Å; Y382-F700 HydrophobicContact CD1-CB 4.02Å; Y382-F700 AromaticContact CD1-CD2 3.25Å; Y382-F700 HydrophobicContact CD1-CD2 3.25Å; Y382-F700 AromaticContact CD1-CE2 4Å; Y382-F700 HydrophobicContact CD1-CE2 4Å; Y382-F700 AromaticContact CD1-CG 3.95Å; Y382-F700 HydrophobicContact CD1-CG 3.95Å; Y382-F700 AromaticContact CE1-CD2 3.88Å; Y382-F700 HydrophobicContact CE1-CD2 3.88Å; Y382-F700 AromaticContact CG-CD2 3.67Å; Y382-F700 HydrophobicContact CG-CD2 3.67Å; Y382-F700 AromaticContact CG-CE2 3.93Å; Y382-F700 HydrophobicContact CG-CE2 3.93Å
383S98.7Very high98.5Very high0 Ų020.3 Ų20.30%010%0.103CC..  trans-149.4140.6168.6133.20000106.2R385 L386 D410S383-R385 PolarHBondContact O-N 2.89Å; S383-R385 WeakPolarHBondContact OG-CB 3.07Å; S383-R385 PolarHBondContact OG-N 3.36Å; S383-R385 VanDerWaalsContact OG-N 3.08Å; S383-L386 VanDerWaalsContact O-CB 3.31Å; S383-L386 WeakPolarHBondContact O-CB 3.45Å; S383-L386 WeakPolarHBondContact O-CG 3.37Å; S383-L386 PolarHBondContact O-N 3.11Å; S383-D410 VanDerWaalsContact CB-OD2 3.24Å; S383-D410 WeakPolarHBondContact CB-OD2 3.35Å; S383-D410 PolarHBondContact OG-OD2 2.79Å
384S98.3Very high98.6Very high33 Ų3320.1 Ų20.123%0.23110%0.102CC..THydrogen-bonded Turntrans-61.2-16.8176.354.10000112.9D697 D701S384-D697 WeakPolarHBondContact CA-OD1 3.4Å; S384-D697 WeakPolarHBondContact CB-OD1 3.16Å; S384-D701 WeakPolarHBondContact CB-OD1 3.06Å; S384-D701 PolarHBondContact OG-OD1 2.69Å
385R98.3Very high98.6Very high129 Ų12919.4 Ų19.449%0.48710%0.097SC..THydrogen-bonded Turntrans-85.32.5173.4-57.6179.2-68.91570.4115M348 S383 D410M348-R385 HydrophobicContact CE-CB 3.97Å; M348-R385 WeakPolarHBondContact CE-O 3.46Å; M348-R385 HydrophobicContact SD-CB 4.49Å; S383-R385 PolarHBondContact O-N 2.89Å; S383-R385 WeakPolarHBondContact OG-CB 3.07Å; S383-R385 PolarHBondContact OG-N 3.36Å; S383-R385 VanDerWaalsContact OG-N 3.08Å; R385-D410 IonicContact CZ-OD1 3.26Å; R385-D410 IonicContact NE-OD1 3.77Å; R385-D410 IonicContact NH2-OD1 2.9Å; R385-D410 PolarHBondContact NH2-OD1 2.57Å
386L98.9Very high98.7Very high6 Ų620.9 Ų20.93%0.03110%0.103CC..SBendtrans-61.5151.2171-72.2174.8000110A346 M348 V356 V380 Y382 S383 E388 F390 K391A346-L386 HydrophobicContact CB-CD2 4.16Å; M348-L386 HydrophobicContact SD-CD2 3.8Å; M348-L386 HydrophobicContact SD-CG 4.43Å; V356-L386 HydrophobicContact CG2-CD2 3.66Å; V380-L386 HydrophobicContact CG1-CD1 4.47Å; Y382-L386 HydrophobicContact CD2-CD1 4.19Å; Y382-L386 HydrophobicContact CG-CD1 4.48Å; S383-L386 VanDerWaalsContact O-CB 3.31Å; S383-L386 WeakPolarHBondContact O-CB 3.45Å; S383-L386 WeakPolarHBondContact O-CG 3.37Å; S383-L386 PolarHBondContact O-N 3.11Å; L386-E388 PolarHBondContact O-N 2.85Å; L386-F390 HydrophobicContact CD1-CD1 4.21Å; L386-F390 HydrophobicContact CD1-CE1 4.35Å; L386-K391 HydrophobicContact CB-CD 4.25Å; L386-K391 HydrophobicContact CB-CG 3.77Å
387P98.7Very high98.7Very high17 Ų1720.7 Ų20.711%0.1110%0.102CC..  trans-56.9136.1175-22.833.4000111.6E45 T354 V356 G389 F390 K391E45-P387 HydrophobicContact CB-CB 4.24Å; E45-P387 HydrophobicContact CB-CG 4.34Å; E45-P387 HydrophobicContact CG-CB 4.49Å; E45-P387 HydrophobicContact CG-CG 4.09Å; T354-P387 HydrophobicContact CG2-CG 3.8Å; V356-P387 HydrophobicContact CB-CG 4.35Å; P387-G389 VanDerWaalsContact C-N 3.3Å; P387-G389 PolarHBondContact O-N 3.25Å; P387-F390 PolarHBondContact O-N 2.69Å; P387-K391 PolarHBondContact O-N 2.85Å
388E98.4Very high98.7Very high101 Ų10120.7 Ų20.747%0.47210%0.102SC..Hα-helixtrans-55.4-45.7-175.7-156.262.9-141.600111.8L386 F390 K391 D392L386-E388 PolarHBondContact O-N 2.85Å; E388-F390 PolarHBondContact O-N 3.13Å; E388-F390 VanDerWaalsContact O-N 3.09Å; E388-K391 PolarHBondContact O-N 3.35Å; E388-K391 VanDerWaalsContact OE1-CE 3.29Å; E388-K391 WeakPolarHBondContact OE1-CE 3.47Å; E388-K391 IonicContact OE1-NZ 2.82Å; E388-K391 PolarHBondContact OE1-NZ 3.03Å; E388-K391 WeakPolarHBondContact OE2-CE 3.35Å; E388-K391 IonicContact OE2-NZ 3.41Å; E388-K391 PolarHBondContact OE2-NZ 3.18Å; E388-D392 WeakPolarHBondContact O-CB 3.26Å; E388-D392 PolarHBondContact O-N 2.82Å
389G98.3Very high98.6Very high18 Ų1821.6 Ų21.619%0.18611%0.106CC..Hα-helixtrans-58.8-27.4178.300000114.3F361 P387 Y393F361-G389 WeakPolarHBondContact CE1-O 3.41Å; P387-G389 VanDerWaalsContact C-N 3.3Å; P387-G389 PolarHBondContact O-N 3.25Å; G389-Y393 VanDerWaalsContact O-CB 3.31Å; G389-Y393 WeakPolarHBondContact O-CB 3.39Å; G389-Y393 PolarHBondContact O-N 3.06Å
390F98.9Very high98.6Very high0 Ų025.1 Ų25.10%013%0.125CC..Hα-helixtrans-83.3-40.1173.9-177.8-96.9000112.2I345 A346 V356 D360 F361 L364 V380 L386 P387 E388 D392 Y393 A394I345-F390 HydrophobicContact CD1-CZ 4.2Å; I345-F390 HydrophobicContact CG1-CZ 4.49Å; A346-F390 HydrophobicContact CB-CD1 4.1Å; A346-F390 HydrophobicContact CB-CE1 3.32Å; A346-F390 HydrophobicContact CB-CZ 3.6Å; V356-F390 HydrophobicContact CG1-CB 3.99Å; V356-F390 HydrophobicContact CG1-CD2 3.9Å; V356-F390 HydrophobicContact CG1-CG 3.88Å; V356-F390 HydrophobicContact CG2-CB 4.39Å; V356-F390 HydrophobicContact CG2-CD1 3.83Å; V356-F390 HydrophobicContact CG2-CD2 4.45Å; V356-F390 HydrophobicContact CG2-CE1 4.26Å; V356-F390 HydrophobicContact CG2-CG 3.94Å; D360-F390 HydrophobicContact CB-CD2 4.38Å; D360-F390 HydrophobicContact CB-CE2 3.63Å; D360-F390 HydrophobicContact CB-CZ 4.16Å; F361-F390 HydrophobicContact CD1-CD2 4.48Å; F361-F390 AromaticContact CD2-CD2 3.79Å; F361-F390 HydrophobicContact CD2-CD2 3.79Å; F361-F390 HydrophobicContact CD2-CE2 4.47Å; F361-F390 HydrophobicContact CE1-CB 4.43Å; F361-F390 HydrophobicContact CE1-CD2 4.26Å; F361-F390 HydrophobicContact CE2-CB 3.85Å; F361-F390 AromaticContact CE2-CD2 3.53Å; F361-F390 HydrophobicContact CE2-CD2 3.53Å; F361-F390 HydrophobicContact CE2-CG 4.16Å; F361-F390 HydrophobicContact CG-CD2 4.27Å; F361-F390 VanDerWaalsContact CZ-CA 3.45Å; F361-F390 HydrophobicContact CZ-CB 3.59Å; F361-F390 AromaticContact CZ-CD2 3.8Å; F361-F390 HydrophobicContact CZ-CD2 3.8Å; F361-F390 HydrophobicContact CZ-CG 4.2Å; L364-F390 HydrophobicContact CD1-CE2 3.68Å; L364-F390 HydrophobicContact CD1-CZ 3.92Å; V380-F390 HydrophobicContact CG1-CE1 3.92Å; L386-F390 HydrophobicContact CD1-CD1 4.21Å; L386-F390 HydrophobicContact CD1-CE1 4.35Å; P387-F390 PolarHBondContact O-N 2.69Å; E388-F390 PolarHBondContact O-N 3.13Å; E388-F390 VanDerWaalsContact O-N 3.09Å; F390-D392 VanDerWaalsContact C-N 3.34Å; F390-Y393 PolarHBondContact O-N 2.73Å; F390-A394 WeakPolarHBondContact O-CB 3.36Å; F390-A394 PolarHBondContact O-N 3.07Å
391K98.8Very high98.5Very high9 Ų925.6 Ų25.64%0.03913%0.128CC..Hα-helixtrans-57.9-49.9175-67-168.7-57.8172.90110.4Y382 L386 P387 E388 Y393 A394 A395 T693 D697Y382-K391 HydrophobicContact CE2-CD 4.43Å; Y382-K391 HydrophobicContact CE2-CG 4.31Å; L386-K391 HydrophobicContact CB-CD 4.25Å; L386-K391 HydrophobicContact CB-CG 3.77Å; P387-K391 PolarHBondContact O-N 2.85Å; E388-K391 PolarHBondContact O-N 3.35Å; E388-K391 VanDerWaalsContact OE1-CE 3.29Å; E388-K391 WeakPolarHBondContact OE1-CE 3.47Å; E388-K391 IonicContact OE1-NZ 2.82Å; E388-K391 PolarHBondContact OE1-NZ 3.03Å; E388-K391 WeakPolarHBondContact OE2-CE 3.35Å; E388-K391 IonicContact OE2-NZ 3.41Å; E388-K391 PolarHBondContact OE2-NZ 3.18Å; K391-Y393 PolarHBondContact O-N 3.25Å; K391-A394 PolarHBondContact O-N 2.69Å; K391-A395 WeakPolarHBondContact O-CB 3.28Å; K391-A395 PolarHBondContact O-N 3.23Å; K391-T693 HydrophobicContact CB-CG2 3.98Å; K391-T693 HydrophobicContact CD-CG2 4.15Å; K391-D697 IonicContact NZ-OD1 2.72Å; K391-D697 IonicContact NZ-OD2 2.67Å; K391-D697 PolarHBondContact NZ-OD2 3.23Å
392D98.6Very high98.5Very high57 Ų5725.8 Ų25.831%0.30513%0.129SC..Hα-helixtrans-61.3-44.8179.7-69.2-16.4000111.7E388 F390 A395 K396 V689 T693E388-D392 WeakPolarHBondContact O-CB 3.26Å; E388-D392 PolarHBondContact O-N 2.82Å; F390-D392 VanDerWaalsContact C-N 3.34Å; D392-A395 PolarHBondContact O-N 2.74Å; D392-K396 WeakPolarHBondContact O-CB 3.42Å; D392-K396 PolarHBondContact O-N 3.03Å; D392-V689 HydrophobicContact CB-CG1 3.75Å; D392-T693 PolarHBondContact OD1-OG1 3.35Å
393Y98.8Very high98.4Very high16 Ų1625.8 Ų25.86%0.06313%0.13CC..Hα-helixtrans-67.4-40.1178.9-173-116.4000112.4A48 L51 F361 L364 H365 E368 G389 F390 K391 K396 I397A48-Y393 HydrophobicContact CB-CD1 4.21Å; A48-Y393 HydrophobicContact CB-CD2 3.43Å; A48-Y393 VanDerWaalsContact CB-CD2 3.43Å; A48-Y393 HydrophobicContact CB-CE1 4.42Å; A48-Y393 HydrophobicContact CB-CE2 3.74Å; A48-Y393 HydrophobicContact CB-CG 3.71Å; L51-Y393 HydrophobicContact CD1-CE1 3.85Å; L51-Y393 HydrophobicContact CD1-CE2 4.16Å; L51-Y393 WeakPolarHBondContact CD1-OH 3.25Å; F361-Y393 HydrophobicContact CB-CD1 4.45Å; F361-Y393 HydrophobicContact CB-CE1 4.33Å; F361-Y393 AromaticContact CD1-CD1 3.34Å; F361-Y393 HydrophobicContact CD1-CD1 3.34Å; F361-Y393 AromaticContact CD1-CE1 3.93Å; F361-Y393 HydrophobicContact CD1-CE1 3.93Å; F361-Y393 AromaticContact CD1-CG 3.87Å; F361-Y393 HydrophobicContact CD1-CG 3.87Å; F361-Y393 AromaticContact CE1-CD1 3.92Å; F361-Y393 HydrophobicContact CE1-CD1 3.92Å; F361-Y393 HydrophobicContact CE1-CG 4.05Å; F361-Y393 HydrophobicContact CG-CD1 4.22Å; L364-Y393 HydrophobicContact CB-CD1 4.31Å; L364-Y393 HydrophobicContact CB-CE1 3.78Å; L364-Y393 HydrophobicContact CD1-CD1 3.99Å; L364-Y393 HydrophobicContact CD1-CE1 4.32Å; H365-Y393 WeakPolarHBondContact CA-OH 3.39Å; H365-Y393 WeakPolarHBondContact CB-OH 3.18Å; H365-Y393 PolarHBondContact ND1-OH 3.5Å; H365-Y393 VanDerWaalsContact ND1-OH 3.07Å; E368-Y393 PolarHBondContact OE2-OH 2.76Å; G389-Y393 VanDerWaalsContact O-CB 3.31Å; G389-Y393 WeakPolarHBondContact O-CB 3.39Å; G389-Y393 PolarHBondContact O-N 3.06Å; F390-Y393 PolarHBondContact O-N 2.73Å; K391-Y393 PolarHBondContact O-N 3.25Å; Y393-K396 PolarHBondContact O-N 3.05Å; Y393-I397 HydrophobicContact CD1-CG1 4.46Å; Y393-I397 HydrophobicContact CE1-CG1 4.16Å; Y393-I397 HydrophobicContact CE2-CD1 4.22Å; Y393-I397 HydrophobicContact CE2-CG1 4.24Å; Y393-I397 VanDerWaalsContact O-CG1 3.28Å; Y393-I397 WeakPolarHBondContact O-CG1 3.33Å; Y393-I397 PolarHBondContact O-N 3.36Å
394A98.8Very high98.4Very high1 Ų125.8 Ų25.81%0.00813%0.13CC..Hα-helixtrans-62.5-44173.600000111.4L364 V380 F390 K391 I397 S398 I404 Y406L364-A394 HydrophobicContact CD1-CB 4.1Å; V380-A394 HydrophobicContact CG2-CB 4.33Å; F390-A394 WeakPolarHBondContact O-CB 3.36Å; F390-A394 PolarHBondContact O-N 3.07Å; K391-A394 PolarHBondContact O-N 2.69Å; A394-I397 PolarHBondContact O-N 2.99Å; A394-S398 PolarHBondContact O-N 3Å; A394-S398 PolarHBondContact O-OG 3.15Å; A394-I404 HydrophobicContact CB-CD1 4.24Å; A394-I404 WeakPolarHBondContact O-CD1 3.47Å; A394-Y406 VanDerWaalsContact C-OH 3.22Å; A394-Y406 HydrophobicContact CB-CE1 4.09Å; A394-Y406 PolarHBondContact O-OH 3.08Å
395A98.6Very high98.4Very high0 Ų024.2 Ų24.20%012%0.119CC..Hα-helixtrans-59.6-45.8175.200000111.7K391 D392 I397 S398 I399 Y406 V689 L692K391-A395 WeakPolarHBondContact O-CB 3.28Å; K391-A395 PolarHBondContact O-N 3.23Å; D392-A395 PolarHBondContact O-N 2.74Å; A395-I397 PolarHBondContact O-N 3.16Å; A395-S398 WeakPolarHBondContact O-CB 3.43Å; A395-S398 PolarHBondContact O-N 3.16Å; A395-S398 VanDerWaalsContact O-N 3.16Å; A395-I399 WeakPolarHBondContact O-CD1 3.39Å; A395-I399 WeakPolarHBondContact O-CG1 3.23Å; A395-I399 PolarHBondContact O-N 3.38Å; A395-Y406 PolarHBondContact N-OH 3.09Å; A395-V689 HydrophobicContact CB-CG1 4.19Å; A395-L692 HydrophobicContact CB-CB 4.22Å; A395-L692 HydrophobicContact CB-CD2 3.93Å; A395-L692 HydrophobicContact CB-CG 4.1Å
396K98.4Very high98.4Very high46 Ų4618.1 Ų18.120%0.210%0.096CC..Hα-helixtrans-54.8-49.3173.2-177.5-174.3179.7-63.40111.7E368 D392 Y393 S398 I399 D400 E685 V689E368-K396 IonicContact OE1-NZ 3.15Å; E368-K396 PolarHBondContact OE1-NZ 3.13Å; D392-K396 WeakPolarHBondContact O-CB 3.42Å; D392-K396 PolarHBondContact O-N 3.03Å; Y393-K396 PolarHBondContact O-N 3.05Å; K396-S398 VanDerWaalsContact C-N 3.3Å; K396-S398 PolarHBondContact O-N 3.26Å; K396-I399 WeakPolarHBondContact O-CB 3.42Å; K396-I399 PolarHBondContact O-N 2.89Å; K396-I399 VanDerWaalsContact O-N 3.09Å; K396-D400 IonicContact NZ-OD2 3.37Å; K396-D400 PolarHBondContact NZ-OD2 3.02Å; K396-D400 PolarHBondContact O-N 3.31Å; K396-E685 WeakPolarHBondContact CE-OE1 3.04Å; K396-V689 HydrophobicContact CB-CG2 4.02Å
397I98.6Very high98.4Very high0 Ų017.8 Ų17.80%09%0.094CC..Hα-helixtrans-61.6-37.9178.8-67.3-68000111.8L364 L367 E368 Y393 A394 A395 D400 T401 I404L364-I397 HydrophobicContact CB-CG1 4.29Å; L364-I397 HydrophobicContact CD2-CG2 4.3Å; L367-I397 HydrophobicContact CB-CG2 4.42Å; L367-I397 HydrophobicContact CD1-CG2 3.53Å; E368-I397 HydrophobicContact CG-CD1 3.75Å; Y393-I397 HydrophobicContact CD1-CG1 4.46Å; Y393-I397 HydrophobicContact CE1-CG1 4.16Å; Y393-I397 HydrophobicContact CE2-CD1 4.22Å; Y393-I397 HydrophobicContact CE2-CG1 4.24Å; Y393-I397 VanDerWaalsContact O-CG1 3.28Å; Y393-I397 WeakPolarHBondContact O-CG1 3.33Å; Y393-I397 PolarHBondContact O-N 3.36Å; A394-I397 PolarHBondContact O-N 2.99Å; A395-I397 PolarHBondContact O-N 3.16Å; I397-D400 PolarHBondContact O-N 2.84Å; I397-T401 HydrophobicContact CG2-CG2 4.48Å; I397-T401 WeakPolarHBondContact O-CB 3.44Å; I397-T401 WeakPolarHBondContact O-CG2 3.4Å; I397-T401 PolarHBondContact O-N 3.32Å; I397-T401 PolarHBondContact O-OG1 3.39Å; I397-I404 HydrophobicContact CG2-CD1 4.31Å; I397-I404 HydrophobicContact CG2-CG2 4.02Å
398S98.5Very high98.4Very high0 Ų017 Ų170%09%0.089CC..Hα-helixtrans-62.1-43.7172.4-73.30000112.5A394 A395 K396 S402 I404 Y406A394-S398 PolarHBondContact O-N 3Å; A394-S398 PolarHBondContact O-OG 3.15Å; A395-S398 WeakPolarHBondContact O-CB 3.43Å; A395-S398 PolarHBondContact O-N 3.16Å; A395-S398 VanDerWaalsContact O-N 3.16Å; K396-S398 VanDerWaalsContact C-N 3.3Å; K396-S398 PolarHBondContact O-N 3.26Å; S398-S402 WeakPolarHBondContact O-CA 3.27Å; S398-S402 PolarHBondContact O-N 3.24Å; S398-S402 PolarHBondContact O-OG 3.46Å; S398-I404 WeakPolarHBondContact OG-CD1 3.35Å; S398-I404 WeakPolarHBondContact OG-CG1 3.45Å; S398-Y406 VanDerWaalsContact OG-CE2 3.32Å; S398-Y406 WeakPolarHBondContact OG-CE2 3.38Å; S398-Y406 PolarHBondContact OG-OH 3.3Å
399I98.1Very high98.4Very high19 Ų1912.2 Ų12.210%0.0977%0.066CC..Hα-helixtrans-61.6-45.5178.3-68.7156.9000110.8A395 K396 L681 R688 V689 L692 V711A395-I399 WeakPolarHBondContact O-CD1 3.39Å; A395-I399 WeakPolarHBondContact O-CG1 3.23Å; A395-I399 PolarHBondContact O-N 3.38Å; K396-I399 WeakPolarHBondContact O-CB 3.42Å; K396-I399 PolarHBondContact O-N 2.89Å; K396-I399 VanDerWaalsContact O-N 3.09Å; I399-L681 HydrophobicContact CD1-CD2 4.27Å; I399-L681 HydrophobicContact CG1-CD2 4.02Å; I399-R688 HydrophobicContact CD1-CB 3.73Å; I399-R688 HydrophobicContact CG1-CB 4.48Å; I399-V689 HydrophobicContact CD1-CB 4.46Å; I399-V689 HydrophobicContact CD1-CG2 3.79Å; I399-L692 HydrophobicContact CD1-CD2 4.28Å; I399-L692 HydrophobicContact CG1-CD2 4Å; I399-V711 HydrophobicContact CG1-CG1 4.38Å; I399-V711 HydrophobicContact CG1-CG2 4.2Å; I399-V711 HydrophobicContact CG2-CG1 4.32Å
400D97.3Very high98.4Very high75 Ų7513.2 Ų13.240%0.4017%0.068SC..Hα-helixtrans-76.7-34-174.7-68.2-20.2000113K396 I397K396-D400 IonicContact NZ-OD2 3.37Å; K396-D400 PolarHBondContact NZ-OD2 3.02Å; K396-D400 PolarHBondContact O-N 3.31Å; I397-D400 PolarHBondContact O-N 2.84Å
401T97.6Very high98.4Very high10 Ų1015 Ų156%0.0618%0.078CC..Hα-helixtrans-125.2-21.5-163.3770000114.8L367 P372 I397 S403L367-T401 HydrophobicContact CB-CG2 4.09Å; P372-T401 HydrophobicContact CG-CG2 4.11Å; I397-T401 HydrophobicContact CG2-CG2 4.48Å; I397-T401 WeakPolarHBondContact O-CB 3.44Å; I397-T401 WeakPolarHBondContact O-CG2 3.4Å; I397-T401 PolarHBondContact O-N 3.32Å; I397-T401 PolarHBondContact O-OG1 3.39Å; T401-S403 PolarHBondContact O-N 3.32Å; T401-S403 PolarHBondContact O-OG 3.29Å; T401-S403 WeakPolarHBondContact OG1-CB 3.34Å; T401-S403 PolarHBondContact OG1-N 3.48Å
402S98.1Very high98.4Very high3 Ų314.6 Ų14.62%0.0218%0.077CC..  trans47.331.3-172.4-60.40000113.6S398 V711 F712 R735S398-S402 WeakPolarHBondContact O-CA 3.27Å; S398-S402 PolarHBondContact O-N 3.24Å; S398-S402 PolarHBondContact O-OG 3.46Å; S402-V711 PolarHBondContact OG-N 2.86Å; S402-F712 WeakPolarHBondContact OG-CD1 3.36Å; S402-R735 VanDerWaalsContact O-CD 3.23Å; S402-R735 WeakPolarHBondContact O-CD 3.06Å; S402-R735 VanDerWaalsContact O-CG 3.26Å; S402-R735 WeakPolarHBondContact O-CG 3.45Å
403S98.1Very high98.3Very high2 Ų212.8 Ų12.81%0.0147%0.066CC..  trans-104.5-12.4-169.6-63.80000113.8T401 T733 R735T401-S403 PolarHBondContact O-N 3.32Å; T401-S403 PolarHBondContact O-OG 3.29Å; T401-S403 WeakPolarHBondContact OG1-CB 3.34Å; T401-S403 PolarHBondContact OG1-N 3.48Å; S403-T733 WeakPolarHBondContact OG-CB 3.45Å; S403-T733 WeakPolarHBondContact OG-CG2 3.37Å; S403-R735 PolarHBondContact O-NH1 3Å
404I97.9Very high98.2Very high0 Ų016.1 Ų16.10%09%0.089CC..  trans-107161-17770.1172.5000112.8L364 L367 L378 V380 A394 I397 S398 Y406 R735L364-I404 HydrophobicContact CD2-CD1 4.07Å; L364-I404 HydrophobicContact CD2-CG2 3.84Å; L367-I404 HydrophobicContact CD1-CG2 3.57Å; L378-I404 HydrophobicContact CB-CB 4.49Å; L378-I404 HydrophobicContact CB-CG2 3.88Å; L378-I404 HydrophobicContact CD1-CG2 4.29Å; V380-I404 HydrophobicContact CG2-CD1 4.11Å; A394-I404 HydrophobicContact CB-CD1 4.24Å; A394-I404 WeakPolarHBondContact O-CD1 3.47Å; I397-I404 HydrophobicContact CG2-CD1 4.31Å; I397-I404 HydrophobicContact CG2-CG2 4.02Å; S398-I404 WeakPolarHBondContact OG-CD1 3.35Å; S398-I404 WeakPolarHBondContact OG-CG1 3.45Å; I404-Y406 HydrophobicContact CD1-CE1 4.38Å; I404-Y406 HydrophobicContact CD1-CE2 4.24Å; I404-Y406 HydrophobicContact CG1-CE2 4.2Å; I404-R735 WeakPolarHBondContact O-CD 3.14Å; I404-R735 PolarHBondContact O-NE 3.05Å
405Q98.7Very high98Very high0 Ų019.6 Ų19.60%011%0.11CC..EExtended strand (participates in β ladder)trans-126.8162.3171.162.6177.120.300111.5N377 L378 T379 V380 E407 C425 H706 N708 R735 G738N377-Q405 PolarHBondContact ND2-NE2 3.28Å; L378-Q405 PolarHBondContact O-N 2.98Å; L378-Q405 VanDerWaalsContact O-N 3.1Å; T379-Q405 WeakPolarHBondContact CA-O 3.4Å; T379-Q405 HydrophobicContact CG2-CG 3.98Å; T379-Q405 WeakPolarHBondContact OG1-CG 3.4Å; T379-Q405 PolarHBondContact OG1-NE2 3.42Å; V380-Q405 PolarHBondContact N-O 3.33Å; Q405-E407 PolarHBondContact NE2-OE1 3.24Å; Q405-C425 PolarHBondContact NE2-O 3.5Å; Q405-H706 PolarHBondContact OE1-NE2 3.43Å; Q405-H706 VanDerWaalsContact OE1-NE2 3.11Å; Q405-N708 WeakPolarHBondContact CB-OD1 3.45Å; Q405-N708 PolarHBondContact OE1-OD1 3.25Å; Q405-R735 VanDerWaalsContact CG-NH2 3.34Å; Q405-G738 PolarHBondContact OE1-O 3.44Å
406Y98.9Very high97.9Very high0 Ų020.2 Ų20.20%011%0.113CC..EExtended strand (participates in β ladder)trans-123.1138.3-178.9-58.1-95.2000110.3V380 Y382 A394 A395 S398 I404 L696 F700 H706 L707 V709V380-Y406 HydrophobicContact CB-CD1 3.62Å; V380-Y406 HydrophobicContact CB-CE1 4.01Å; V380-Y406 HydrophobicContact CB-CG 4.39Å; V380-Y406 HydrophobicContact CG1-CD1 3.78Å; V380-Y406 HydrophobicContact CG1-CE1 4.1Å; V380-Y406 HydrophobicContact CG2-CD1 4.18Å; V380-Y406 HydrophobicContact CG2-CE1 4.09Å; V380-Y406 WeakPolarHBondContact O-CA 3.3Å; Y382-Y406 AromaticContact CD2-CD1 3.68Å; Y382-Y406 HydrophobicContact CD2-CD1 3.68Å; Y382-Y406 HydrophobicContact CD2-CE1 4.13Å; Y382-Y406 HydrophobicContact CE2-CD1 4.39Å; Y382-Y406 HydrophobicContact CE2-CE1 4.49Å; Y382-Y406 HydrophobicContact CG-CD1 4.37Å; A394-Y406 VanDerWaalsContact C-OH 3.22Å; A394-Y406 HydrophobicContact CB-CE1 4.09Å; A394-Y406 PolarHBondContact O-OH 3.08Å; A395-Y406 PolarHBondContact N-OH 3.09Å; S398-Y406 VanDerWaalsContact OG-CE2 3.32Å; S398-Y406 WeakPolarHBondContact OG-CE2 3.38Å; S398-Y406 PolarHBondContact OG-OH 3.3Å; I404-Y406 HydrophobicContact CD1-CE1 4.38Å; I404-Y406 HydrophobicContact CD1-CE2 4.24Å; I404-Y406 HydrophobicContact CG1-CE2 4.2Å; Y406-L696 HydrophobicContact CD1-CD1 4.21Å; Y406-L696 HydrophobicContact CD1-CD2 4.23Å; Y406-L696 HydrophobicContact CD2-CD2 3.85Å; Y406-L696 HydrophobicContact CE1-CD1 3.77Å; Y406-L696 HydrophobicContact CE1-CD2 4.5Å; Y406-L696 HydrophobicContact CE2-CD1 4.19Å; Y406-L696 HydrophobicContact CE2-CD2 4.15Å; Y406-L696 HydrophobicContact CG-CD2 3.88Å; Y406-F700 HydrophobicContact CG-CE2 4.4Å; Y406-H706 CarbonylContact O-C 3.32Å; Y406-H706 VanDerWaalsContact O-CA 3.28Å; Y406-H706 WeakPolarHBondContact O-CA 3.48Å; Y406-L707 PolarHBondContact N-O 3.18Å; Y406-L707 PolarHBondContact O-N 3.48Å; Y406-V709 HydrophobicContact CD2-CG2 3.82Å; Y406-V709 HydrophobicContact CE2-CB 4.29Å; Y406-V709 HydrophobicContact CE2-CG2 3.73Å
407E98.8Very high97.8Very high0 Ų021.1 Ų21.10%012%0.119CC..EExtended strand (participates in β ladder)trans-134.9141.9174.1-58.7-163.5-132.900111T379 V380 L381 Y382 Q405 D409 M412 I422 V426 H705 H706T379-E407 HydrophobicContact CG2-CB 4.33Å; T379-E407 HydrophobicContact CG2-CG 3.76Å; T379-E407 WeakPolarHBondContact CG2-OE1 3.04Å; V380-E407 PolarHBondContact O-N 3Å; L381-E407 CarbonylContact C-O 3.52Å; L381-E407 WeakPolarHBondContact CA-O 3.47Å; Y382-E407 PolarHBondContact N-O 3.06Å; Q405-E407 PolarHBondContact NE2-OE1 3.24Å; E407-D409 PolarHBondContact O-N 2.98Å; E407-D409 VanDerWaalsContact O-N 3.13Å; E407-M412 HydrophobicContact CB-CE 3.37Å; E407-I422 WeakPolarHBondContact OE1-CG1 3.21Å; E407-I422 WeakPolarHBondContact OE1-CG2 3.32Å; E407-I422 WeakPolarHBondContact OE2-CD1 3.28Å; E407-V426 WeakPolarHBondContact OE2-CA 3.37Å; E407-H705 CarbonylContact C-O 3.4Å; E407-H705 VanDerWaalsContact CA-O 3.32Å; E407-H705 WeakPolarHBondContact CA-O 3.38Å; E407-H705 IonicContact OE2-CE1 3.67Å; E407-H705 PolarHBondContact OE2-CE1 3.34Å; E407-H705 IonicContact OE2-ND1 3.41Å; E407-H705 IonicContact OE2-NE2 2.77Å; E407-H706 HydrophobicContact CG-CB 3.91Å
408N98.7Very high97.8Very high0 Ų021.2 Ų21.20%012%0.12CC..EExtended strand (participates in β ladder)trans-77.4101-167.3-169.5-17.6000112.9D410 V411 M412 F700 A704 H705N408-D410 PolarHBondContact O-N 3.47Å; N408-D410 WeakPolarHBondContact OD1-CB 3.47Å; N408-D410 PolarHBondContact OD1-N 3.22Å; N408-V411 HydrophobicContact CB-CG2 3.7Å; N408-V411 WeakPolarHBondContact O-CG2 3.36Å; N408-V411 PolarHBondContact O-N 3.32Å; N408-V411 PolarHBondContact OD1-N 3.13Å; N408-M412 WeakPolarHBondContact O-CB 3.37Å; N408-M412 VanDerWaalsContact O-CE 3.26Å; N408-M412 WeakPolarHBondContact O-CE 3.07Å; N408-M412 WeakPolarHBondContact O-CG 3.46Å; N408-M412 PolarHBondContact O-N 3.13Å; N408-M412 VanDerWaalsContact O-N 3.12Å; N408-F700 HydrophobicContact CB-CD1 3.5Å; N408-F700 VanDerWaalsContact CB-CD1 3.5Å; N408-F700 HydrophobicContact CB-CE1 3.96Å; N408-F700 HydrophobicContact CB-CG 4.27Å; N408-F700 PolarHBondContact ND2-O 3.43Å; N408-A704 WeakPolarHBondContact CB-O 3.43Å; N408-A704 PolarHBondContact ND2-O 3.34Å; N408-H705 WeakPolarHBondContact CB-O 3.34Å; N408-H705 PolarHBondContact N-O 3.46Å
409D98.8Very high97.8Very high0 Ų022 Ų220%012%0.124CC..Hα-helixtrans-65.7-27.4177-166.350.8000112.1G347 M348 L381 Y382 E407 V411 R413 Y420G347-D409 WeakPolarHBondContact CA-OD2 3.28Å; M348-D409 PolarHBondContact N-OD2 3.02Å; L381-D409 HydrophobicContact CB-CB 4.09Å; Y382-D409 VanDerWaalsContact O-CB 3.28Å; Y382-D409 WeakPolarHBondContact O-CB 3.44Å; Y382-D409 PolarHBondContact O-N 2.95Å; E407-D409 PolarHBondContact O-N 2.98Å; E407-D409 VanDerWaalsContact O-N 3.13Å; D409-V411 PolarHBondContact O-N 2.79Å; D409-R413 WeakPolarHBondContact O-CB 3.39Å; D409-R413 PolarHBondContact O-N 3.43Å; D409-R413 IonicContact OD2-CZ 3.69Å; D409-R413 IonicContact OD2-NH1 3.68Å; D409-R413 PolarHBondContact OD2-NH1 3.35Å; D409-Y420 WeakPolarHBondContact CA-OH 3.45Å; D409-Y420 WeakPolarHBondContact OD1-CE1 3.47Å; D409-Y420 VanDerWaalsContact OD1-CZ 3.31Å; D409-Y420 PolarHBondContact OD1-OH 3.32Å
410D98.4Very high97.8Very high40 Ų4021 Ų2121%0.21412%0.119CC..Hα-helixtrans-72.8-27.7-178.7-72.9-41.7000113.5S383 R385 N408 R413 P414S383-D410 VanDerWaalsContact CB-OD2 3.24Å; S383-D410 WeakPolarHBondContact CB-OD2 3.35Å; S383-D410 PolarHBondContact OG-OD2 2.79Å; R385-D410 IonicContact CZ-OD1 3.26Å; R385-D410 IonicContact NE-OD1 3.77Å; R385-D410 IonicContact NH2-OD1 2.9Å; R385-D410 PolarHBondContact NH2-OD1 2.57Å; N408-D410 PolarHBondContact O-N 3.47Å; N408-D410 WeakPolarHBondContact OD1-CB 3.47Å; N408-D410 PolarHBondContact OD1-N 3.22Å; D410-R413 IonicContact OD1-CZ 2.84Å; D410-R413 IonicContact OD1-NH1 3.43Å; D410-R413 PolarHBondContact OD1-NH1 3.12Å; D410-R413 IonicContact OD1-NH2 2.69Å; D410-R413 PolarHBondContact OD1-NH2 3.04Å; D410-P414 WeakPolarHBondContact O-CD 3.42Å; D410-P414 WeakPolarHBondContact O-CG 3.47Å
411V97.6Very high97.8Very high37 Ų3717.5 Ų17.522%0.22410%0.1CC..Hα-helixtrans-90.9-30.3172.5-55.80000113.1N408 D409 Y663N408-V411 HydrophobicContact CB-CG2 3.7Å; N408-V411 WeakPolarHBondContact O-CG2 3.36Å; N408-V411 PolarHBondContact O-N 3.32Å; N408-V411 PolarHBondContact OD1-N 3.13Å; D409-V411 PolarHBondContact O-N 2.79Å; V411-Y663 HydrophobicContact CB-CD1 4.31Å; V411-Y663 HydrophobicContact CG2-CD1 3.92Å; V411-Y663 HydrophobicContact CG2-CE1 4.44Å; V411-Y663 HydrophobicContact CG2-CG 4.46Å
412M98.4Very high97.9Very high0 Ų017 Ų170%010%0.097CC..Hα-helixtrans-82.2-44.2-178.4-74.2-169-71.500113L381 E407 N408 P414 V415 W416 Y420 I422 A428 Y663L381-M412 HydrophobicContact CD2-CE 4.1Å; E407-M412 HydrophobicContact CB-CE 3.37Å; N408-M412 WeakPolarHBondContact O-CB 3.37Å; N408-M412 VanDerWaalsContact O-CE 3.26Å; N408-M412 WeakPolarHBondContact O-CE 3.07Å; N408-M412 WeakPolarHBondContact O-CG 3.46Å; N408-M412 PolarHBondContact O-N 3.13Å; N408-M412 VanDerWaalsContact O-N 3.12Å; M412-P414 VanDerWaalsContact C-CD 3.45Å; M412-P414 VanDerWaalsContact C-N 3.34Å; M412-V415 WeakPolarHBondContact O-CA 3.26Å; M412-V415 WeakPolarHBondContact O-CB 3.39Å; M412-V415 PolarHBondContact O-N 3.31Å; M412-W416 PolarHBondContact O-N 2.89Å; M412-Y420 HydrophobicContact CB-CE1 4.42Å; M412-Y420 HydrophobicContact CB-CE2 3.9Å; M412-Y420 HydrophobicContact CE-CE2 3.83Å; M412-Y420 WeakPolarHBondContact CE-OH 3.42Å; M412-Y420 HydrophobicContact CG-CE2 4.47Å; M412-Y420 HydrophobicContact SD-CE2 3.72Å; M412-I422 HydrophobicContact CE-CD1 4.17Å; M412-I422 HydrophobicContact SD-CD1 3.84Å; M412-A428 HydrophobicContact SD-CB 3.91Å; M412-Y663 HydrophobicContact CG-CE1 3.85Å
413R97.9Very high97.8Very high19 Ų1916.9 Ų16.97%0.07210%0.096CC..Hα-helixtrans-57.3-36.3-176-174.5178.865.5-113.4-17.2114M348 M350 D409 D410 V415 L417 D418 Y420M348-R413 VanDerWaalsContact CB-NH1 3.3Å; M348-R413 WeakPolarHBondContact O-CD 3.37Å; M350-R413 HydrophobicContact SD-CG 3.62Å; D409-R413 WeakPolarHBondContact O-CB 3.39Å; D409-R413 PolarHBondContact O-N 3.43Å; D409-R413 IonicContact OD2-CZ 3.69Å; D409-R413 IonicContact OD2-NH1 3.68Å; D409-R413 PolarHBondContact OD2-NH1 3.35Å; D410-R413 IonicContact OD1-CZ 2.84Å; D410-R413 IonicContact OD1-NH1 3.43Å; D410-R413 PolarHBondContact OD1-NH1 3.12Å; D410-R413 IonicContact OD1-NH2 2.69Å; D410-R413 PolarHBondContact OD1-NH2 3.04Å; R413-V415 PolarHBondContact O-N 2.89Å; R413-L417 WeakPolarHBondContact CA-O 3.25Å; R413-L417 WeakPolarHBondContact CG-O 3.42Å; R413-L417 CarbonylContact O-C 3.51Å; R413-L417 WeakPolarHBondContact O-CA 3.41Å; R413-L417 PolarHBondContact O-N 3.36Å; R413-D418 HydrophobicContact CG-CB 4.39Å; R413-Y420 HydrophobicContact CB-CE1 4.4Å
414P96.3Very high97.8Very high87 Ų8717 Ų1757%0.56510%0.097SC*.Hα-helixtrans-62.5-27.3172.3-2536.1000114.6D410 M412D410-P414 WeakPolarHBondContact O-CD 3.42Å; D410-P414 WeakPolarHBondContact O-CG 3.47Å; M412-P414 VanDerWaalsContact C-CD 3.45Å; M412-P414 VanDerWaalsContact C-N 3.34Å
415V95.3Very high97.7Very high74 Ų7417 Ų1745%0.44810%0.097SC..Hα-helixtrans-88.8-47.3-179.6-176.90000110.9M412 R413 L667M412-V415 WeakPolarHBondContact O-CA 3.26Å; M412-V415 WeakPolarHBondContact O-CB 3.39Å; M412-V415 PolarHBondContact O-N 3.31Å; R413-V415 PolarHBondContact O-N 2.89Å; V415-L667 HydrophobicContact CG1-CD2 4.36Å
416W95.8Very high97.7Very high12 Ų1217 Ų175%0.04510%0.097CC..Hα-helixtrans-106.42.4-168-46.7105.8000114.3M412 Y420 A428 E434 Y663 L667M412-W416 PolarHBondContact O-N 2.89Å; W416-Y420 VanDerWaalsContact CB-CB 3.45Å; W416-Y420 HydrophobicContact CB-CD1 4.06Å; W416-Y420 HydrophobicContact CB-CD2 4.3Å; W416-Y420 HydrophobicContact CB-CG 3.69Å; W416-Y420 HydrophobicContact CG-CG 4.45Å; W416-A428 HydrophobicContact CD2-CB 4.05Å; W416-A428 HydrophobicContact CG-CB 3.96Å; W416-A428 HydrophobicContact CZ2-CB 4.32Å; W416-E434 WeakPolarHBondContact CZ3-OE2 3.3Å; W416-Y663 AromaticContact NE1-CZ 3.99Å; W416-Y663 PolarHBondContact NE1-OH 3.5Å; W416-L667 HydrophobicContact CZ2-CB 4.13Å; W416-L667 HydrophobicContact CZ2-CD2 4.33Å
417L96.3Very high97.7Very high66 Ų6617 Ų1735%0.34610%0.097SC..  trans64.5-160.1-170.7-51.9-178.2000112.3M350 R413 Y420M350-L417 HydrophobicContact CE-CD2 4.33Å; R413-L417 WeakPolarHBondContact CA-O 3.25Å; R413-L417 WeakPolarHBondContact CG-O 3.42Å; R413-L417 CarbonylContact O-C 3.51Å; R413-L417 WeakPolarHBondContact O-CA 3.41Å; R413-L417 PolarHBondContact O-N 3.36Å; L417-Y420 WeakPolarHBondContact O-CD1 3.3Å
418D98.2Very high97.6Very high2 Ų217 Ų171%0.01110%0.097CC..SBendtrans-102.76-17153.614.4000114.5R34 Q38 R285 M350 L355 R413R34-D418 IonicContact CZ-OD1 3.23Å; R34-D418 VanDerWaalsContact CZ-OD1 3.31Å; R34-D418 IonicContact CZ-OD2 2.77Å; R34-D418 IonicContact NE-OD1 3.73Å; R34-D418 PolarHBondContact NE-OD1 3.03Å; R34-D418 IonicContact NE-OD2 2.76Å; R34-D418 VanDerWaalsContact NH2-CG 3.32Å; R34-D418 IonicContact NH2-OD1 3.63Å; R34-D418 PolarHBondContact NH2-OD1 3.24Å; R34-D418 IonicContact NH2-OD2 3.19Å; R34-D418 PolarHBondContact NH2-OD2 2.98Å; Q38-D418 PolarHBondContact NE2-OD2 2.65Å; R285-D418 PolarHBondContact NH1-O 2.96Å; R285-D418 VanDerWaalsContact NH1-O 3.08Å; M350-D418 WeakPolarHBondContact CB-OD2 3.26Å; M350-D418 HydrophobicContact CG-CB 3.94Å; M350-D418 VanDerWaalsContact CG-OD2 3.26Å; M350-D418 WeakPolarHBondContact CG-OD2 3.37Å; M350-D418 PolarHBondContact N-OD2 3.24Å; L355-D418 HydrophobicContact CD1-CB 4.12Å; L355-D418 VanDerWaalsContact CD1-O 3.32Å; L355-D418 WeakPolarHBondContact CD1-O 3.38Å; R413-D418 HydrophobicContact CG-CB 4.39Å
419D98.3Very high97.5Very high15 Ų1517.1 Ų17.18%0.0810%0.098CC..SBendtrans-127.132.8176.7-167.339000112.2R34 R193 T431R34-D419 HydrophobicContact CB-CB 3.96Å; R34-D419 HydrophobicContact CG-CB 3.65Å; R193-D419 IonicContact CZ-OD1 3.8Å; R193-D419 IonicContact CZ-OD2 2.84Å; R193-D419 IonicContact NH1-OD1 2.94Å; R193-D419 PolarHBondContact NH1-OD1 3.43Å; R193-D419 IonicContact NH1-OD2 3.04Å; R193-D419 IonicContact NH2-OD1 2.78Å; R193-D419 PolarHBondContact NH2-OD1 3.33Å; R193-D419 IonicContact NH2-OD2 3.9Å; R193-D419 PolarHBondContact NH2-OD2 3.04Å; D419-T431 VanDerWaalsContact O-CB 3.23Å; D419-T431 WeakPolarHBondContact O-CB 3.32Å; D419-T431 PolarHBondContact O-N 2.91Å; D419-T431 PolarHBondContact O-OG1 3.44Å
420Y98.5Very high97.4Very high0 Ų019 Ų190%011%0.106CC..EExtended strand (participates in β ladder)trans-81.6157.4167.676.5-77.8000110.9R285 L381 D409 M412 R413 W416 L417 I422 A428 T429R285-Y420 WeakPolarHBondContact CD-O 3.44Å; R285-Y420 PolarHBondContact NH1-O 3.08Å; L381-Y420 HydrophobicContact CD1-CE1 4.27Å; L381-Y420 HydrophobicContact CD1-CE2 4.2Å; L381-Y420 HydrophobicContact CD2-CE2 3.88Å; D409-Y420 WeakPolarHBondContact CA-OH 3.45Å; D409-Y420 WeakPolarHBondContact OD1-CE1 3.47Å; D409-Y420 VanDerWaalsContact OD1-CZ 3.31Å; D409-Y420 PolarHBondContact OD1-OH 3.32Å; M412-Y420 HydrophobicContact CB-CE1 4.42Å; M412-Y420 HydrophobicContact CB-CE2 3.9Å; M412-Y420 HydrophobicContact CE-CE2 3.83Å; M412-Y420 WeakPolarHBondContact CE-OH 3.42Å; M412-Y420 HydrophobicContact CG-CE2 4.47Å; M412-Y420 HydrophobicContact SD-CE2 3.72Å; R413-Y420 HydrophobicContact CB-CE1 4.4Å; W416-Y420 VanDerWaalsContact CB-CB 3.45Å; W416-Y420 HydrophobicContact CB-CD1 4.06Å; W416-Y420 HydrophobicContact CB-CD2 4.3Å; W416-Y420 HydrophobicContact CB-CG 3.69Å; W416-Y420 HydrophobicContact CG-CG 4.45Å; L417-Y420 WeakPolarHBondContact O-CD1 3.3Å; Y420-I422 HydrophobicContact CD2-CD1 4.31Å; Y420-I422 HydrophobicContact CE2-CD1 3.98Å; Y420-A428 HydrophobicContact CD2-CB 3.84Å; Y420-A428 HydrophobicContact CE2-CB 4.27Å; Y420-T429 CarbonylContact C-O 3.4Å; Y420-T429 WeakPolarHBondContact CA-O 3.48Å; Y420-T429 VanDerWaalsContact CB-O 3.26Å; Y420-T429 WeakPolarHBondContact CB-O 3.32Å
421A98.2Very high97.2Very high0 Ų017.3 Ų17.30%010%0.098CC..EExtended strand (participates in β ladder)trans-126.7159172.100000110.1R285 A428 T429R285-A421 HydrophobicContact CB-CB 4.09Å; A421-A428 WeakPolarHBondContact O-CA 3.48Å; A421-T429 PolarHBondContact N-O 2.83Å; A421-T429 PolarHBondContact O-N 3.41Å
422I98.6Very high97.1Very high0 Ų015.6 Ų15.60%09%0.087CC..EExtended strand (participates in β ladder)trans-88.1126.1170.6-56.9-53.1000108.5T342 S344 T379 L381 E407 M412 Y420 A428T342-I422 HydrophobicContact CG2-CB 4.05Å; T342-I422 HydrophobicContact CG2-CG2 3.97Å; T342-I422 WeakPolarHBondContact CG2-O 3.33Å; S344-I422 PolarHBondContact OG-N 2.76Å; T379-I422 HydrophobicContact CG2-CB 4.3Å; T379-I422 HydrophobicContact CG2-CG1 3.83Å; L381-I422 HydrophobicContact CD2-CD1 4.25Å; L381-I422 HydrophobicContact CD2-CG1 3.96Å; E407-I422 WeakPolarHBondContact OE1-CG1 3.21Å; E407-I422 WeakPolarHBondContact OE1-CG2 3.32Å; E407-I422 WeakPolarHBondContact OE2-CD1 3.28Å; M412-I422 HydrophobicContact CE-CD1 4.17Å; M412-I422 HydrophobicContact SD-CD1 3.84Å; Y420-I422 HydrophobicContact CD2-CD1 4.31Å; Y420-I422 HydrophobicContact CE2-CD1 3.98Å; I422-A428 HydrophobicContact CD1-CB 4.06Å
423C97Very high97.1Very high0 Ų018.9 Ų18.90%010%0.102CC..EExtended strand (participates in β ladder)trans-99.7140.3169.2-162.80000110.4R187 V189 C425 S427 T429R187-C423 WeakPolarHBondContact CA-SG 3.42Å; V189-C423 HydrophobicContact CG2-CB 3.78Å; V189-C423 VanDerWaalsContact CG2-SG 3.59Å; C423-C425 PolarHBondContact O-N 2.75Å; C423-S427 PolarHBondContact N-O 2.84Å; C423-S427 WeakPolarHBondContact O-CB 3.4Å; C423-S427 PolarHBondContact O-N 3.47Å; C423-T429 HydrophobicContact CB-CG2 4.33Å
424C96.9Very high97Very high4 Ų419.1 Ų19.13%0.02710%0.104CC..THydrogen-bonded Turntrans59.8-103.5-176.7-171.70000111.5A280 S282 T342 N377A280-C424 HydrophobicContact CB-CB 3.41Å; A280-C424 VanDerWaalsContact CB-CB 3.41Å; S282-C424 PolarHBondContact OG-N 2.99Å; T342-C424 PolarHBondContact OG1-O 3.05Å; N377-C424 PolarHBondContact ND2-O 3.21Å
425C96.6Very high97Very high0 Ų015 Ų150%08%0.077CC..THydrogen-bonded Turntrans-110.2-53.8-171.6-70.20000113W340 Q405 C423 L611 I613 G738W340-C425 VanDerWaalsContact CD1-SG 3.55Å; W340-C425 PolarHBondContact NE1-SG 3.27Å; Q405-C425 PolarHBondContact NE2-O 3.5Å; C423-C425 PolarHBondContact O-N 2.75Å; C425-L611 HydrophobicContact CB-CD1 3.93Å; C425-L611 HydrophobicContact CB-CD2 4Å; C425-I613 WeakPolarHBondContact SG-CD1 3.11Å; C425-G738 VanDerWaalsContact CA-O 3.3Å; C425-G738 WeakPolarHBondContact CA-O 3.19Å; C425-G738 VanDerWaalsContact CB-O 3.3Å; C425-G738 WeakPolarHBondContact CB-O 3.41Å; C425-G738 PolarHBondContact SG-O 2.83Å
426V98.3Very high97.2Very high0 Ų011.7 Ų11.70%06%0.056CC..THydrogen-bonded Turntrans-146.113.7-164.9-70.70000112.1E407 L611 D668 G669 H705 H706E407-V426 WeakPolarHBondContact OE2-CA 3.37Å; V426-L611 HydrophobicContact CG2-CD1 4.38Å; V426-L611 HydrophobicContact CG2-CD2 4.17Å; V426-D668 CarbonylContact C-O 3.48Å; V426-G669 VanDerWaalsContact O-CA 3.3Å; V426-G669 WeakPolarHBondContact O-CA 3.44Å; V426-H705 PolarHBondContact O-CE1 3.48Å; V426-H706 HydrophobicContact CG1-CB 3.71Å; V426-H706 WeakPolarHBondContact CG1-CD2 3.28Å
427S98.3Very high97.3Very high0 Ų011.1 Ų11.10%05%0.054CC..EExtended strand (participates in β ladder)trans-105.493.5-166.8-49.50000109.8R187 C423 Q436 D668R187-S427 VanDerWaalsContact NH1-CB 3.32Å; R187-S427 PolarHBondContact NH1-OG 3.25Å; R187-S427 PolarHBondContact NH2-OG 3.38Å; C423-S427 PolarHBondContact N-O 2.84Å; C423-S427 WeakPolarHBondContact O-CB 3.4Å; C423-S427 PolarHBondContact O-N 3.47Å; S427-Q436 PolarHBondContact O-NE2 2.95Å; S427-D668 WeakPolarHBondContact CA-O 3.49Å; S427-D668 WeakPolarHBondContact CB-O 3.49Å; S427-D668 WeakPolarHBondContact CB-OD1 3.37Å; S427-D668 PolarHBondContact OG-O 3.19Å; S427-D668 PolarHBondContact OG-OD1 3.11Å
428A97.8Very high97.4Very high1 Ų18.2 Ų8.21%0.0084%0.039CC..EExtended strand (participates in β ladder)trans-62.3139.7177.300000111.7M412 W416 Y420 A421 I422 Q436M412-A428 HydrophobicContact SD-CB 3.91Å; W416-A428 HydrophobicContact CD2-CB 4.05Å; W416-A428 HydrophobicContact CG-CB 3.96Å; W416-A428 HydrophobicContact CZ2-CB 4.32Å; Y420-A428 HydrophobicContact CD2-CB 3.84Å; Y420-A428 HydrophobicContact CE2-CB 4.27Å; A421-A428 WeakPolarHBondContact O-CA 3.48Å; I422-A428 HydrophobicContact CD1-CB 4.06Å; A428-Q436 PolarHBondContact O-NE2 3.22Å
429T95.9Very high97.4Very high2 Ų28.1 Ų8.11%0.0124%0.039CC..EExtended strand (participates in β ladder)trans-142.6141.6171.9176.40000109.8V189 Y420 A421 C423 T431 E434V189-T429 HydrophobicContact CB-CG2 4.42Å; V189-T429 HydrophobicContact CG2-CG2 4.13Å; Y420-T429 CarbonylContact C-O 3.4Å; Y420-T429 WeakPolarHBondContact CA-O 3.48Å; Y420-T429 VanDerWaalsContact CB-O 3.26Å; Y420-T429 WeakPolarHBondContact CB-O 3.32Å; A421-T429 PolarHBondContact N-O 2.83Å; A421-T429 PolarHBondContact O-N 3.41Å; C423-T429 HydrophobicContact CB-CG2 4.33Å; T429-T431 PolarHBondContact O-N 3.3Å; T429-E434 VanDerWaalsContact OG1-C 3.31Å; T429-E434 WeakPolarHBondContact OG1-CB 3.27Å; T429-E434 PolarHBondContact OG1-O 3.09Å
430Q96.1Very high97.3Very high39 Ų397.6 Ų7.618%0.1824%0.036CC..EExtended strand (participates in β ladder)trans-69.8117.2169.7-163.5-178.528.500110.3G432 K433 E434Q430-G432 PolarHBondContact O-N 3.44Å; Q430-K433 HydrophobicContact CB-CB 4.22Å; Q430-K433 HydrophobicContact CG-CB 4.18Å; Q430-K433 HydrophobicContact CG-CD 4.08Å; Q430-K433 PolarHBondContact O-N 3.05Å; Q430-E434 HydrophobicContact CB-CG 3.87Å; Q430-E434 PolarHBondContact O-N 3.31Å; Q430-E434 VanDerWaalsContact O-N 3.15Å
431T95.5Very high97.3Very high6 Ų67.7 Ų7.74%0.0374%0.036CC..THydrogen-bonded Turntrans-56.8125.9-171.1-50.30000111.5D191 D419 T429 K433D191-T431 HydrophobicContact CB-CG2 4.02Å; D419-T431 VanDerWaalsContact O-CB 3.23Å; D419-T431 WeakPolarHBondContact O-CB 3.32Å; D419-T431 PolarHBondContact O-N 2.91Å; D419-T431 PolarHBondContact O-OG1 3.44Å; T429-T431 PolarHBondContact O-N 3.3Å; T431-K433 PolarHBondContact O-N 3.26Å
432G95.9Very high97.3Very high0 Ų07.7 Ų7.70%04%0.036CC..THydrogen-bonded Turntrans70.16.8178.900000115.6R194 Q430 M521 D522R194-G432 PolarHBondContact NH2-O 3.06Å; Q430-G432 PolarHBondContact O-N 3.44Å; G432-M521 CarbonylContact O-C 3.5Å; G432-M521 WeakPolarHBondContact O-CA 3.26Å; G432-M521 WeakPolarHBondContact O-CB 3.38Å; G432-D522 PolarHBondContact O-N 2.86Å
433K96.8Very high97.3Very high69 Ų697.7 Ų7.730%0.34%0.036SC..THydrogen-bonded Turntrans-125.7-24.4-176.2-66.3-177.2178.1-66.20113.4Q430 T431 D522 L525 K526Q430-K433 HydrophobicContact CB-CB 4.22Å; Q430-K433 HydrophobicContact CG-CB 4.18Å; Q430-K433 HydrophobicContact CG-CD 4.08Å; Q430-K433 PolarHBondContact O-N 3.05Å; T431-K433 PolarHBondContact O-N 3.26Å; K433-D522 IonicContact NZ-OD2 3.83Å; K433-D522 PolarHBondContact NZ-OD2 3.22Å; K433-L525 WeakPolarHBondContact O-CD2 3.45Å; K433-K526 PolarHBondContact O-N 3.4Å
434E96Very high97.4Very high24 Ų247.7 Ų7.711%0.1124%0.036CC..EExtended strand (participates in β ladder)trans-138151.4-176.5-47.2-173.1155.400111.5W416 T429 Q430 M521 K526W416-E434 WeakPolarHBondContact CZ3-OE2 3.3Å; T429-E434 VanDerWaalsContact OG1-C 3.31Å; T429-E434 WeakPolarHBondContact OG1-CB 3.27Å; T429-E434 PolarHBondContact OG1-O 3.09Å; Q430-E434 HydrophobicContact CB-CG 3.87Å; Q430-E434 PolarHBondContact O-N 3.31Å; Q430-E434 VanDerWaalsContact O-N 3.15Å; E434-M521 WeakPolarHBondContact O-CE 3.36Å; E434-K526 WeakPolarHBondContact CA-O 3.38Å; E434-K526 HydrophobicContact CB-CB 4.31Å; E434-K526 HydrophobicContact CG-CB 3.82Å; E434-K526 HydrophobicContact CG-CD 4.29Å; E434-K526 WeakPolarHBondContact OE1-CD 3.46Å
435M96.9Very high97.5Very high2 Ų27.5 Ų7.51%0.014%0.035CC..EExtended strand (participates in β ladder)trans-136.5159.4172.664.6172.4-72.500110.3I188 F437 L518 M521 L525 K526 R527 T528I188-M435 HydrophobicContact CD1-CE 3.65Å; I188-M435 HydrophobicContact CG1-CB 4.21Å; I188-M435 HydrophobicContact CG1-CE 3.76Å; M435-F437 HydrophobicContact CE-CD1 3.84Å; M435-F437 HydrophobicContact CE-CE1 3.69Å; M435-L518 HydrophobicContact SD-CD2 3.82Å; M435-M521 HydrophobicContact CB-CE 4.47Å; M435-L525 HydrophobicContact CG-CD1 4.48Å; M435-L525 HydrophobicContact SD-CD1 4.22Å; M435-K526 PolarHBondContact N-O 3.25Å; M435-K526 VanDerWaalsContact N-O 3.12Å; M435-R527 HydrophobicContact CG-CG 3.81Å; M435-R527 WeakPolarHBondContact O-CA 3.32Å; M435-R527 HydrophobicContact SD-CG 4.26Å; M435-T528 PolarHBondContact O-N 3.08Å; M435-T528 VanDerWaalsContact O-N 3.1Å
436Q98.5Very high97.6Very high3 Ų37.5 Ų7.51%0.0144%0.035CC..EExtended strand (participates in β ladder)trans-111.3134.1174.7-49.799.6-19.100111.3R187 S427 A428 F438 T528 A530R187-Q436 HydrophobicContact CB-CB 4.13Å; R187-Q436 WeakPolarHBondContact CB-O 3.48Å; R187-Q436 PolarHBondContact O-N 3.44Å; R187-Q436 VanDerWaalsContact O-N 3.16Å; R187-Q436 PolarHBondContact O-OE1 3.38Å; R187-Q436 VanDerWaalsContact O-OE1 3.1Å; S427-Q436 PolarHBondContact O-NE2 2.95Å; A428-Q436 PolarHBondContact O-NE2 3.22Å; Q436-F438 PolarHBondContact O-N 2.82Å; Q436-T528 WeakPolarHBondContact CB-OG1 3.48Å; Q436-T528 WeakPolarHBondContact CG-OG1 3Å; Q436-A530 HydrophobicContact CB-CB 4.07Å
437F98.7Very high97.6Very high0 Ų07.5 Ų7.50%04%0.035CC..EExtended strand (participates in β ladder)trans-77.7102.8164.8-79.2-27000109.1M435 G439 H505 R527 T528 F529 A530 Y601 R602M435-F437 HydrophobicContact CE-CD1 3.84Å; M435-F437 HydrophobicContact CE-CE1 3.69Å; F437-G439 PolarHBondContact O-N 3.22Å; F437-H505 VanDerWaalsContact C-CE1 3.5Å; F437-H505 HydrophobicContact CD1-CB 4.08Å; F437-H505 AromaticContact CD1-CG 3.88Å; F437-H505 AromaticContact CD1-ND1 3.78Å; F437-H505 HydrophobicContact CD2-CB 4.19Å; F437-H505 HydrophobicContact CE1-CB 4.28Å; F437-H505 HydrophobicContact CE2-CB 4.34Å; F437-H505 HydrophobicContact CG-CB 4.04Å; F437-H505 AromaticContact CG-CD2 3.98Å; F437-H505 AromaticContact CG-CG 3.67Å; F437-H505 AromaticContact CG-ND1 3.87Å; F437-H505 HydrophobicContact CZ-CB 4.37Å; F437-R527 HydrophobicContact CE2-CB 4.47Å; F437-T528 PolarHBondContact N-O 3.4Å; F437-F529 HydrophobicContact CB-CD2 4.2Å; F437-F529 HydrophobicContact CD2-CD2 4.1Å; F437-A530 WeakPolarHBondContact O-CB 3.44Å; F437-A530 PolarHBondContact O-N 3.08Å; F437-Y601 HydrophobicContact CD2-CD1 4.3Å; F437-Y601 AromaticContact CE2-CD1 3.49Å; F437-Y601 HydrophobicContact CE2-CD1 3.49Å; F437-Y601 VanDerWaalsContact CE2-CD1 3.49Å; F437-Y601 AromaticContact CE2-CE1 3.93Å; F437-Y601 HydrophobicContact CE2-CE1 3.93Å; F437-Y601 AromaticContact CZ-CD1 3.76Å; F437-Y601 HydrophobicContact CZ-CD1 3.76Å; F437-Y601 AromaticContact CZ-CE1 3.69Å; F437-Y601 HydrophobicContact CZ-CE1 3.69Å; F437-R602 HydrophobicContact CE2-CB 4.43Å
438F98.5Very high97.6Very high6 Ų67.5 Ų7.53%0.0264%0.035CC..EExtended strand (participates in β ladder)trans-65.4124-174-175.8-134.1000113.8P180 Y183 R185 R187 A279 F334 Q436 A440 H505P180-F438 HydrophobicContact CB-CD1 4.34Å; P180-F438 HydrophobicContact CG-CB 4.49Å; P180-F438 HydrophobicContact CG-CD1 4.04Å; P180-F438 WeakPolarHBondContact CG-O 3.42Å; Y183-F438 HydrophobicContact CE2-CD1 4.42Å; Y183-F438 HydrophobicContact CE2-CE1 4.14Å; R185-F438 HydrophobicContact CB-CB 4.39Å; R185-F438 WeakPolarHBondContact O-CB 3.4Å; R185-F438 WeakPolarHBondContact O-CD1 3.4Å; R187-F438 HydrophobicContact CB-CB 3.98Å; R187-F438 HydrophobicContact CG-CB 3.47Å; R187-F438 VanDerWaalsContact CG-CB 3.47Å; R187-F438 HydrophobicContact CG-CD2 3.59Å; R187-F438 HydrophobicContact CG-CG 3.66Å; A279-F438 HydrophobicContact CB-CE1 4.08Å; F334-F438 HydrophobicContact CZ-CE1 4.43Å; Q436-F438 PolarHBondContact O-N 2.82Å; F438-A440 HydrophobicContact CE1-CB 4.2Å; F438-A440 HydrophobicContact CZ-CB 3.93Å; F438-H505 PolarHBondContact N-CE1 3.36Å; F438-H505 PolarHBondContact O-CE1 2.99Å; F438-H505 PolarHBondContact O-NE2 3.04Å
439G98.2Very high97.7Very high0 Ų07.6 Ų7.60%04%0.036CC..  trans-100.4-11.4179.600000116.3L179 F437 R441 Y497 L501 A530L179-G439 WeakPolarHBondContact CG-O 3.23Å; F437-G439 PolarHBondContact O-N 3.22Å; G439-R441 PolarHBondContact O-N 3.23Å; G439-Y497 WeakPolarHBondContact O-CE2 3.23Å; G439-Y497 PolarHBondContact O-OH 3.43Å; G439-L501 VanDerWaalsContact CA-CD1 3.5Å; G439-A530 WeakPolarHBondContact CA-O 3.36Å; G439-A530 PolarHBondContact N-O 2.76Å
440A96.8Very high97.8Very high4 Ų47.5 Ų7.53%0.0334%0.035CC..  trans57.8-121.6-158.900000110.9G178 F438 Y497 G532G178-A440 WeakPolarHBondContact O-CB 3.47Å; F438-A440 HydrophobicContact CE1-CB 4.2Å; F438-A440 HydrophobicContact CZ-CB 3.93Å; A440-Y497 PolarHBondContact O-OH 2.73Å; A440-G532 WeakPolarHBondContact O-CA 3.47Å
441R98.3Very high97.9Very high1 Ų15.7 Ų5.70%0.0043%0.027CC..  trans-159.5152-177.874.5-66.8-78.2-178.82113.5G439 Y497 G532 A534 L611 T612 S615 Y619G439-R441 PolarHBondContact O-N 3.23Å; R441-Y497 WeakPolarHBondContact CA-OH 3.41Å; R441-Y497 PolarHBondContact N-OH 3.04Å; R441-Y497 VanDerWaalsContact N-OH 3.08Å; R441-G532 CarbonylContact C-O 3.45Å; R441-G532 VanDerWaalsContact CA-O 3.24Å; R441-G532 WeakPolarHBondContact CA-O 3.46Å; R441-G532 WeakPolarHBondContact CB-O 3.48Å; R441-A534 HydrophobicContact CG-CB 3.77Å; R441-L611 PolarHBondContact NE-O 2.88Å; R441-T612 PolarHBondContact NE-O 3.21Å; R441-T612 PolarHBondContact NH1-O 3.48Å; R441-T612 PolarHBondContact NH2-O 3.39Å; R441-S615 VanDerWaalsContact CD-CB 3.5Å; R441-S615 WeakPolarHBondContact CD-OG 3.46Å; R441-S615 PolarHBondContact NH1-OG 2.9Å; R441-Y619 HydrophobicContact CG-CE2 3.92Å; R441-Y619 PolarHBondContact O-OH 3.41Å
442A98.6Very high98.1Very high0 Ų05.5 Ų5.50%03%0.026CC..EExtended strand (participates in β ladder)trans-98152.5174.300000112.2I176 L444 L493 Y497 G532 A534 F591I176-A442 HydrophobicContact CG2-CB 3.82Å; A442-L444 HydrophobicContact CB-CD1 4.21Å; A442-L444 PolarHBondContact O-N 3.08Å; A442-L493 HydrophobicContact CB-CD1 4.25Å; A442-L493 HydrophobicContact CB-CD2 4.12Å; A442-L493 HydrophobicContact CB-CG 4.33Å; A442-Y497 HydrophobicContact CB-CD1 3.71Å; A442-Y497 HydrophobicContact CB-CE1 3.74Å; A442-Y497 HydrophobicContact CB-CG 4.4Å; A442-G532 PolarHBondContact N-O 2.84Å; A442-A534 WeakPolarHBondContact O-CB 3.33Å; A442-A534 PolarHBondContact O-N 3.19Å; A442-F591 HydrophobicContact CB-CZ 4.45Å
443N98.7Very high98.2Very high0 Ų05.8 Ų5.80%03%0.027CC..EExtended strand (participates in β ladder)trans-91.791.1-178.4-174.8-6.1000111K174 I175 A445 K446 A447 Y619 T623K174-N443 PolarHBondContact O-ND2 3.19Å; K174-N443 VanDerWaalsContact O-ND2 3.1Å; I175-N443 PolarHBondContact O-N 2.71Å; N443-A445 VanDerWaalsContact C-N 3.31Å; N443-A445 PolarHBondContact O-N 2.82Å; N443-A445 PolarHBondContact OD1-N 3.13Å; N443-K446 HydrophobicContact CB-CB 4.21Å; N443-K446 VanDerWaalsContact CG-CB 3.45Å; N443-K446 VanDerWaalsContact ND2-CB 3.3Å; N443-K446 WeakPolarHBondContact ND2-CB 3.41Å; N443-K446 PolarHBondContact O-N 3.26Å; N443-K446 PolarHBondContact OD1-N 2.89Å; N443-A447 PolarHBondContact O-N 3.46Å; N443-Y619 HydrophobicContact CB-CD1 3.65Å; N443-Y619 HydrophobicContact CB-CD2 4.09Å; N443-Y619 HydrophobicContact CB-CE1 3.7Å; N443-Y619 HydrophobicContact CB-CE2 4.14Å; N443-Y619 HydrophobicContact CB-CG 3.85Å; N443-Y619 WeakPolarHBondContact ND2-CD1 3.42Å; N443-T623 PolarHBondContact ND2-OG1 3.47Å
444L98.8Very high98.3Very high0 Ų02.5 Ų2.50%01%0.013CC..Hα-helixtrans-71.1-28.9-179.8-8867.2000111.9A442 K446 A447 L448 Y486 L490 L493 I533 A534 V539 V587 F591A442-L444 HydrophobicContact CB-CD1 4.21Å; A442-L444 PolarHBondContact O-N 3.08Å; L444-K446 PolarHBondContact O-N 3.35Å; L444-A447 WeakPolarHBondContact O-CB 3.42Å; L444-A447 PolarHBondContact O-N 3.44Å; L444-L448 PolarHBondContact O-N 3.09Å; L444-Y486 PolarHBondContact O-OH 3.45Å; L444-L490 HydrophobicContact CD2-CD2 4.28Å; L444-L490 HydrophobicContact CG-CD2 4.04Å; L444-L493 HydrophobicContact CD1-CD2 4.12Å; L444-I533 HydrophobicContact CB-CG2 4.43Å; L444-I533 HydrophobicContact CD1-CB 4.38Å; L444-I533 HydrophobicContact CD1-CG1 4.18Å; L444-I533 HydrophobicContact CD1-CG2 4.02Å; L444-I533 HydrophobicContact CD2-CD1 4.39Å; L444-I533 HydrophobicContact CD2-CG1 4.16Å; L444-I533 HydrophobicContact CD2-CG2 3.71Å; L444-I533 HydrophobicContact CG-CG2 4.25Å; L444-A534 PolarHBondContact N-O 2.87Å; L444-V539 HydrophobicContact CB-CG2 4.09Å; L444-V587 HydrophobicContact CD2-CG1 3.97Å; L444-F591 HydrophobicContact CD1-CD1 4.4Å; L444-F591 HydrophobicContact CD1-CE1 4.09Å; L444-F591 HydrophobicContact CD1-CE2 4.33Å; L444-F591 HydrophobicContact CD1-CZ 4.05Å; L444-F591 HydrophobicContact CD2-CB 4.36Å; L444-F591 HydrophobicContact CD2-CD1 4.41Å; L444-F591 HydrophobicContact CD2-CD2 4.44Å; L444-F591 HydrophobicContact CD2-CG 4.16Å
445A98.6Very high98.4Very high0 Ų01.4 Ų1.40%01%0.008CC..Hα-helixtrans-60.7-46.7174.400000111.7N443 A447 L448 L449 V539 T623 M626 L636N443-A445 VanDerWaalsContact C-N 3.31Å; N443-A445 PolarHBondContact O-N 2.82Å; N443-A445 PolarHBondContact OD1-N 3.13Å; A445-A447 VanDerWaalsContact C-N 3.32Å; A445-A447 PolarHBondContact O-N 3.06Å; A445-L448 WeakPolarHBondContact O-CB 3.36Å; A445-L448 PolarHBondContact O-N 3.11Å; A445-L449 PolarHBondContact O-N 3.36Å; A445-V539 HydrophobicContact CB-CG2 4.35Å; A445-T623 HydrophobicContact CB-CG2 4.35Å; A445-M626 HydrophobicContact CB-CE 3.69Å; A445-M626 HydrophobicContact CB-SD 4Å; A445-M626 WeakPolarHBondContact O-CE 3.25Å; A445-L636 HydrophobicContact CB-CD1 4.27Å; A445-L636 HydrophobicContact CB-CD2 3.93Å
446K98.6Very high98.4Very high0 Ų02.3 Ų2.30%01%0.014CC..Hα-helixtrans-66.4-34.1175-179.7171.5-77.5-720112.5A173 I175 N443 L444 L448 L449 Y450 D457 E458 A622 T623A173-K446 WeakPolarHBondContact O-CD 3.41Å; A173-K446 VanDerWaalsContact O-CE 3.26Å; A173-K446 WeakPolarHBondContact O-CE 3.36Å; I175-K446 HydrophobicContact CB-CD 4.05Å; I175-K446 HydrophobicContact CD1-CG 4.29Å; I175-K446 HydrophobicContact CG1-CD 4.46Å; I175-K446 HydrophobicContact CG1-CG 4.4Å; N443-K446 HydrophobicContact CB-CB 4.21Å; N443-K446 VanDerWaalsContact CG-CB 3.45Å; N443-K446 VanDerWaalsContact ND2-CB 3.3Å; N443-K446 WeakPolarHBondContact ND2-CB 3.41Å; N443-K446 PolarHBondContact O-N 3.26Å; N443-K446 PolarHBondContact OD1-N 2.89Å; L444-K446 PolarHBondContact O-N 3.35Å; K446-L448 VanDerWaalsContact C-N 3.26Å; K446-L448 PolarHBondContact O-N 2.85Å; K446-L449 PolarHBondContact O-N 2.92Å; K446-L449 VanDerWaalsContact O-N 3.12Å; K446-Y450 HydrophobicContact CD-CE1 3.87Å; K446-Y450 HydrophobicContact CG-CD1 3.89Å; K446-Y450 HydrophobicContact CG-CE1 3.45Å; K446-Y450 VanDerWaalsContact CG-CE1 3.45Å; K446-Y450 VanDerWaalsContact O-CD1 3.27Å; K446-Y450 WeakPolarHBondContact O-CD1 3.49Å; K446-Y450 PolarHBondContact O-N 3.24Å; K446-D457 IonicContact NZ-OD2 3.26Å; K446-D457 PolarHBondContact NZ-OD2 3.32Å; K446-E458 IonicContact NZ-OE1 2.71Å; K446-E458 PolarHBondContact NZ-OE1 3.37Å; K446-E458 IonicContact NZ-OE2 3.7Å; K446-E458 PolarHBondContact NZ-OE2 3.38Å; K446-A622 WeakPolarHBondContact CE-O 3.47Å; K446-A622 PolarHBondContact NZ-O 3.25Å; K446-T623 HydrophobicContact CB-CG2 4.4Å
447A98.7Very high98.4Very high0 Ų02.5 Ų2.50%02%0.015CC..Hα-helixtrans-60.3-36.4173.600000112.4I175 N443 L444 A445 Y450 A451 Y486 V489 L490 L493I175-A447 HydrophobicContact CD1-CB 4.31Å; N443-A447 PolarHBondContact O-N 3.46Å; L444-A447 WeakPolarHBondContact O-CB 3.42Å; L444-A447 PolarHBondContact O-N 3.44Å; A445-A447 VanDerWaalsContact C-N 3.32Å; A445-A447 PolarHBondContact O-N 3.06Å; A447-Y450 PolarHBondContact O-N 2.98Å; A447-A451 PolarHBondContact O-N 3.17Å; A447-Y486 HydrophobicContact CB-CE2 3.95Å; A447-V489 HydrophobicContact CB-CG1 3.95Å; A447-V489 WeakPolarHBondContact O-CG1 3.48Å; A447-L490 HydrophobicContact CB-CD2 4.48Å; A447-L493 HydrophobicContact CB-CD2 3.88Å
448L98.8Very high98.3Very high0 Ų03 Ų30%02%0.017CC..Hα-helixtrans-64.2-40.2173.6-176.661.8000111.8L444 A445 K446 Y450 A451 I452 V482 Y486 L543 M626 P627L444-L448 PolarHBondContact O-N 3.09Å; A445-L448 WeakPolarHBondContact O-CB 3.36Å; A445-L448 PolarHBondContact O-N 3.11Å; K446-L448 VanDerWaalsContact C-N 3.26Å; K446-L448 PolarHBondContact O-N 2.85Å; L448-Y450 VanDerWaalsContact C-N 3.32Å; L448-Y450 PolarHBondContact O-N 2.74Å; L448-A451 WeakPolarHBondContact O-CB 3.36Å; L448-A451 PolarHBondContact O-N 2.8Å; L448-I452 WeakPolarHBondContact O-CG1 3.46Å; L448-I452 PolarHBondContact O-N 3.34Å; L448-V482 HydrophobicContact CD1-CG1 3.8Å; L448-Y486 HydrophobicContact CB-CD2 4.06Å; L448-Y486 HydrophobicContact CB-CE2 3.81Å; L448-Y486 HydrophobicContact CD1-CD1 4.19Å; L448-Y486 HydrophobicContact CD1-CD2 3.87Å; L448-Y486 HydrophobicContact CD1-CE2 4.32Å; L448-Y486 HydrophobicContact CD1-CG 3.8Å; L448-Y486 VanDerWaalsContact N-CE2 3.35Å; L448-L543 HydrophobicContact CD1-CD2 4.22Å; L448-M626 HydrophobicContact CB-CE 4.41Å; L448-M626 HydrophobicContact CD2-CE 3.99Å; L448-P627 HydrophobicContact CD2-CG 4.48Å
449L98.8Very high98.2Very high3 Ų38.2 Ų8.22%0.0164%0.04CC..Hα-helixtrans-65.8-36.1174.4-59.1-174.6000112A445 K446 A451 I452 N453 E458 F564 T623 M626A445-L449 PolarHBondContact O-N 3.36Å; K446-L449 PolarHBondContact O-N 2.92Å; K446-L449 VanDerWaalsContact O-N 3.12Å; L449-A451 VanDerWaalsContact C-N 3.3Å; L449-A451 PolarHBondContact O-N 3.38Å; L449-I452 PolarHBondContact O-N 3.41Å; L449-N453 WeakPolarHBondContact O-CB 3.38Å; L449-N453 PolarHBondContact O-N 3.49Å; L449-E458 HydrophobicContact CD1-CG 3.87Å; L449-F564 HydrophobicContact CD2-CE2 4.01Å; L449-F564 HydrophobicContact CD2-CZ 4.19Å; L449-T623 HydrophobicContact CD1-CG2 3.72Å; L449-M626 HydrophobicContact CD1-SD 3.9Å; L449-M626 HydrophobicContact CD2-SD 3.73Å; L449-M626 HydrophobicContact CG-SD 3.69Å
450Y98.7Very high98.1Very high0 Ų011.6 Ų11.60%06%0.063CC..Hα-helixtrans-66-34.7174.9-79.428.6000111.3A173 I175 K446 A447 L448 I452 N453 G454 G455 D457 V464 W492A173-Y450 WeakPolarHBondContact CB-OH 3.27Å; I175-Y450 HydrophobicContact CD1-CD2 3.58Å; I175-Y450 HydrophobicContact CD1-CE2 3.52Å; I175-Y450 HydrophobicContact CD1-CG 4.15Å; K446-Y450 HydrophobicContact CD-CE1 3.87Å; K446-Y450 HydrophobicContact CG-CD1 3.89Å; K446-Y450 HydrophobicContact CG-CE1 3.45Å; K446-Y450 VanDerWaalsContact CG-CE1 3.45Å; K446-Y450 VanDerWaalsContact O-CD1 3.27Å; K446-Y450 WeakPolarHBondContact O-CD1 3.49Å; K446-Y450 PolarHBondContact O-N 3.24Å; A447-Y450 PolarHBondContact O-N 2.98Å; L448-Y450 VanDerWaalsContact C-N 3.32Å; L448-Y450 PolarHBondContact O-N 2.74Å; Y450-I452 VanDerWaalsContact C-N 3.31Å; Y450-I452 PolarHBondContact O-N 2.88Å; Y450-N453 CarbonylContact O-C 3.58Å; Y450-N453 PolarHBondContact O-N 3.46Å; Y450-G454 PolarHBondContact O-N 3.02Å; Y450-G455 PolarHBondContact O-N 3.49Å; Y450-D457 HydrophobicContact CE1-CB 3.92Å; Y450-D457 WeakPolarHBondContact CE1-OD2 3.35Å; Y450-D457 WeakPolarHBondContact OH-CB 3.49Å; Y450-D457 PolarHBondContact OH-OD2 2.83Å; Y450-V464 HydrophobicContact CE2-CB 3.82Å; Y450-V464 HydrophobicContact CE2-CG1 3.97Å; Y450-W492 HydrophobicContact CD2-CH2 4.38Å; Y450-W492 HydrophobicContact CD2-CZ3 4.13Å; Y450-W492 HydrophobicContact CE2-CH2 4.29Å; Y450-W492 HydrophobicContact CE2-CZ3 4.46Å
451A98.6Very high98.1Very high2 Ų215.6 Ų15.62%0.0178%0.08CC..Hα-helixtrans-63.6-38.1174.600000112A447 L448 L449 K485 Y486 V489A447-A451 PolarHBondContact O-N 3.17Å; L448-A451 WeakPolarHBondContact O-CB 3.36Å; L448-A451 PolarHBondContact O-N 2.8Å; L449-A451 VanDerWaalsContact C-N 3.3Å; L449-A451 PolarHBondContact O-N 3.38Å; A451-K485 HydrophobicContact CB-CB 4.03Å; A451-K485 WeakPolarHBondContact O-CD 3.31Å; A451-Y486 HydrophobicContact CB-CD2 4.25Å; A451-V489 HydrophobicContact CB-CB 4.39Å; A451-V489 HydrophobicContact CB-CG2 3.88Å
452I98.6Very high98Very high1 Ų117.7 Ų17.71%0.00510%0.098CC..Hα-helixtrans-71.6-43176.3-63.7168.4000110.9L448 L449 Y450 I471 L477 V561 F564 P627L448-I452 WeakPolarHBondContact O-CG1 3.46Å; L448-I452 PolarHBondContact O-N 3.34Å; L449-I452 PolarHBondContact O-N 3.41Å; Y450-I452 VanDerWaalsContact C-N 3.31Å; Y450-I452 PolarHBondContact O-N 2.88Å; I452-I471 HydrophobicContact CG1-CD1 4.17Å; I452-I471 PolarHBondContact O-N 3.4Å; I452-L477 HydrophobicContact CD1-CD1 4.1Å; I452-V561 HydrophobicContact CG2-CB 4.01Å; I452-V561 HydrophobicContact CG2-CG1 4.34Å; I452-V561 HydrophobicContact CG2-CG2 3.78Å; I452-F564 HydrophobicContact CD1-CE1 4.06Å; I452-F564 HydrophobicContact CD1-CZ 3.79Å; I452-P627 HydrophobicContact CD1-CG 4.07Å
453N98.5Very high98Very high6 Ų621.8 Ų21.83%0.03212%0.117CC..Hα-helixtrans-9611.7-172.8-73.1-35000115.1L449 Y450 G455 V456 V561L449-N453 WeakPolarHBondContact O-CB 3.38Å; L449-N453 PolarHBondContact O-N 3.49Å; Y450-N453 CarbonylContact O-C 3.58Å; Y450-N453 PolarHBondContact O-N 3.46Å; N453-G455 PolarHBondContact O-N 3.46Å; N453-V456 WeakPolarHBondContact O-CB 3.09Å; N453-V456 PolarHBondContact O-N 3.34Å; N453-V561 PolarHBondContact ND2-O 3.18Å; N453-V561 VanDerWaalsContact OD1-CB 3.26Å; N453-V561 WeakPolarHBondContact OD1-CB 3.09Å; N453-V561 WeakPolarHBondContact OD1-CG2 3.17Å; N453-V561 PolarHBondContact OD1-N 3.04Å
454G97.8Very high98Very high1 Ų122.8 Ų22.81%0.0112%0.123CC..THydrogen-bonded Turntrans68.933.4175.300000114.7Y450 V456 Q463 F468Y450-G454 PolarHBondContact O-N 3.02Å; G454-V456 VanDerWaalsContact C-N 3.27Å; G454-V456 PolarHBondContact O-N 3.5Å; G454-Q463 PolarHBondContact O-NE2 3.1Å; G454-F468 CarbonylContact C-O 3.54Å; G454-F468 WeakPolarHBondContact CA-O 3.45Å; G454-F468 PolarHBondContact O-N 3.31Å
455G98Very high97.9Very high0 Ų023.1 Ų23.10%013%0.126CC..THydrogen-bonded Turntrans80.50.4-17800000115.1Y450 N453 Q463 V464 G465Y450-G455 PolarHBondContact O-N 3.49Å; N453-G455 PolarHBondContact O-N 3.46Å; G455-Q463 PolarHBondContact O-NE2 3Å; G455-V464 PolarHBondContact O-N 3.13Å; G455-V464 VanDerWaalsContact O-N 3.13Å; G455-G465 PolarHBondContact O-N 3.09Å
456V98.3Very high97.9Very high22 Ų2225.5 Ų25.513%0.13314%0.142CC..BIsolated β-bridgetrans-78.1131.3171.9-177.70000110N453 G454 E458 I560N453-V456 WeakPolarHBondContact O-CB 3.09Å; N453-V456 PolarHBondContact O-N 3.34Å; G454-V456 VanDerWaalsContact C-N 3.27Å; G454-V456 PolarHBondContact O-N 3.5Å; V456-E458 PolarHBondContact O-N 2.84Å; V456-I560 HydrophobicContact CB-CD1 4.09Å; V456-I560 HydrophobicContact CG1-CD1 3.75Å; V456-I560 HydrophobicContact CG1-CG1 4.44Å; V456-I560 HydrophobicContact CG2-CD1 4.38Å
457D98.2Very high97.8Very high6 Ų632.3 Ų32.33%0.03218%0.178CC..  trans-71.4123.3174-176.5-103.9000111.2K446 Y450 K459 S460 K461 A462 V464K446-D457 IonicContact NZ-OD2 3.26Å; K446-D457 PolarHBondContact NZ-OD2 3.32Å; Y450-D457 HydrophobicContact CE1-CB 3.92Å; Y450-D457 WeakPolarHBondContact CE1-OD2 3.35Å; Y450-D457 WeakPolarHBondContact OH-CB 3.49Å; Y450-D457 PolarHBondContact OH-OD2 2.83Å; D457-K459 PolarHBondContact O-N 3.45Å; D457-K459 VanDerWaalsContact O-N 3.13Å; D457-K459 PolarHBondContact OD1-N 3.08Å; D457-S460 WeakPolarHBondContact CB-OG 3.17Å; D457-S460 WeakPolarHBondContact OD1-CB 3.37Å; D457-S460 PolarHBondContact OD1-N 3.25Å; D457-S460 PolarHBondContact OD1-OG 3.08Å; D457-K461 WeakPolarHBondContact O-CA 3.45Å; D457-K461 PolarHBondContact O-N 3.21Å; D457-A462 PolarHBondContact N-O 2.8Å; D457-V464 HydrophobicContact CB-CG2 3.95Å
458E97.5Very high97.7Very high12 Ų1234.3 Ų34.36%0.05619%0.187CC..THydrogen-bonded Turntrans-67.6-16.6-172.377.5-69.6172.600113.9K446 L449 V456 I560 T623 G624K446-E458 IonicContact NZ-OE1 2.71Å; K446-E458 PolarHBondContact NZ-OE1 3.37Å; K446-E458 IonicContact NZ-OE2 3.7Å; K446-E458 PolarHBondContact NZ-OE2 3.38Å; L449-E458 HydrophobicContact CD1-CG 3.87Å; V456-E458 PolarHBondContact O-N 2.84Å; E458-I560 HydrophobicContact CB-CG2 4.45Å; E458-T623 WeakPolarHBondContact OE1-CA 3.2Å; E458-G624 PolarHBondContact OE1-N 2.9Å
459K96Very high97.5Very high114 Ų11442.1 Ų42.150%0.49622%0.216SC..THydrogen-bonded Turntrans-99.4-49.8179.4-64.5-164.275.8178.10112.5D457 K621 A622D457-K459 PolarHBondContact O-N 3.45Å; D457-K459 VanDerWaalsContact O-N 3.13Å; D457-K459 PolarHBondContact OD1-N 3.08Å; K459-K621 PolarHBondContact NZ-O 3.22Å; K459-A622 WeakPolarHBondContact CD-O 3.32Å
460S95.9Very high97.4Very high71 Ų7144.2 Ų44.250%0.49723%0.23SC..THydrogen-bonded Turntrans-86.7-14-176.863.20000113.4D457 A462D457-S460 WeakPolarHBondContact CB-OG 3.17Å; D457-S460 WeakPolarHBondContact OD1-CB 3.37Å; D457-S460 PolarHBondContact OD1-N 3.25Å; D457-S460 PolarHBondContact OD1-OG 3.08Å; S460-A462 PolarHBondContact O-N 3.23Å; S460-A462 VanDerWaalsContact O-N 3.13Å
461K96.4Very high97.3Very high89 Ų8944.3 Ų44.339%0.38723%0.23SC..  trans60.215-175.7-50-175.8174.7-161.70113.6D457 D556 D558D457-K461 WeakPolarHBondContact O-CA 3.45Å; D457-K461 PolarHBondContact O-N 3.21Å; K461-D556 WeakPolarHBondContact CE-OD2 3.48Å; K461-D556 IonicContact NZ-OD2 3.85Å; K461-D556 PolarHBondContact NZ-OD2 2.82Å; K461-D558 VanDerWaalsContact CD-OD2 3.29Å; K461-D558 WeakPolarHBondContact CD-OD2 3.24Å; K461-D558 IonicContact NZ-OD2 3.46Å; K461-D558 PolarHBondContact NZ-OD2 3.45Å
462A97Very high97Very high45 Ų4549.6 Ų49.637%0.37226%0.255SS..  trans-87.2142.517800000110.3D457 S460 V464D457-A462 PolarHBondContact N-O 2.8Å; S460-A462 PolarHBondContact O-N 3.23Å; S460-A462 VanDerWaalsContact O-N 3.13Å; A462-V464 HydrophobicContact CB-CG2 4.27Å; A462-V464 PolarHBondContact O-N 2.76Å
463Q97.6Very high96.7Very high86 Ų8651.9 Ų51.940%0.40227%0.271SS..BIsolated β-bridgetrans-68.9110165.7-168.668.445.300108.6G454 G455 G465 P466G454-Q463 PolarHBondContact O-NE2 3.1Å; G455-Q463 PolarHBondContact O-NE2 3Å; Q463-G465 WeakPolarHBondContact CG-O 3.32Å; Q463-G465 PolarHBondContact NE2-O 3.34Å; Q463-P466 PolarHBondContact NE2-O 3.12Å
464V98.1Very high96.3Very high21 Ų2157 Ų5713%0.12730%0.298CS..  trans-111.6-48.6-178.5176.90000110.4A169 A173 Y450 G455 D457 A462A169-V464 HydrophobicContact CB-CG1 4.48Å; A173-V464 HydrophobicContact CB-CB 4.37Å; A173-V464 HydrophobicContact CB-CG1 3.85Å; A173-V464 HydrophobicContact CB-CG2 3.81Å; Y450-V464 HydrophobicContact CE2-CB 3.82Å; Y450-V464 HydrophobicContact CE2-CG1 3.97Å; G455-V464 PolarHBondContact O-N 3.13Å; G455-V464 VanDerWaalsContact O-N 3.13Å; D457-V464 HydrophobicContact CB-CG2 3.95Å; A462-V464 HydrophobicContact CB-CG2 4.27Å; A462-V464 PolarHBondContact O-N 2.76Å
465G97.4Very high96.2Very high7 Ų762.6 Ų62.67%0.07233%0.328CS..SBendtrans-75.1173.9168.500000111.9G455 Q463G455-G465 PolarHBondContact O-N 3.09Å; Q463-G465 WeakPolarHBondContact CG-O 3.32Å; Q463-G465 PolarHBondContact NE2-O 3.34Å
466P97.7Very high96.2Very high49 Ų4964.2 Ų64.232%0.31834%0.342SS..  trans-51.4152.7166.6-23.233.4000111.1Q463 F468 W492Q463-P466 PolarHBondContact NE2-O 3.12Å; P466-F468 HydrophobicContact CB-CD1 4.39Å; P466-F468 HydrophobicContact CB-CD2 4.07Å; P466-F468 HydrophobicContact CB-CE1 4.09Å; P466-F468 HydrophobicContact CB-CE2 3.77Å; P466-F468 HydrophobicContact CB-CG 4.39Å; P466-F468 HydrophobicContact CB-CZ 3.77Å; P466-F468 HydrophobicContact CG-CD2 4.41Å; P466-F468 HydrophobicContact CG-CE1 4.39Å; P466-F468 HydrophobicContact CG-CE2 3.66Å; P466-F468 HydrophobicContact CG-CZ 3.65Å; P466-F468 WeakPolarHBondContact O-CD2 3.46Å; P466-F468 PolarHBondContact O-N 3.33Å; P466-W492 VanDerWaalsContact CD-CD1 3.49Å; P466-W492 HydrophobicContact CG-CB 4.24Å; P466-W492 VanDerWaalsContact CG-CD1 3.45Å; P466-W492 HydrophobicContact CG-CD2 4.28Å; P466-W492 HydrophobicContact CG-CG 3.71Å
467D97Very high96.2Very high143 Ų14363.6 Ų63.677%0.76534%0.338SS*.  trans-72.169176-172.517.4000110.2
468F96.3Very high96.2Very high42 Ų4267.5 Ų67.518%0.18436%0.358CS..PPolyproline II helixtrans-73.2152.1175.3-65.7-61.8000109.4G454 P466 P470 E488 V489 W492G454-F468 CarbonylContact C-O 3.54Å; G454-F468 WeakPolarHBondContact CA-O 3.45Å; G454-F468 PolarHBondContact O-N 3.31Å; P466-F468 HydrophobicContact CB-CD1 4.39Å; P466-F468 HydrophobicContact CB-CD2 4.07Å; P466-F468 HydrophobicContact CB-CE1 4.09Å; P466-F468 HydrophobicContact CB-CE2 3.77Å; P466-F468 HydrophobicContact CB-CG 4.39Å; P466-F468 HydrophobicContact CB-CZ 3.77Å; P466-F468 HydrophobicContact CG-CD2 4.41Å; P466-F468 HydrophobicContact CG-CE1 4.39Å; P466-F468 HydrophobicContact CG-CE2 3.66Å; P466-F468 HydrophobicContact CG-CZ 3.65Å; P466-F468 WeakPolarHBondContact O-CD2 3.46Å; P466-F468 PolarHBondContact O-N 3.33Å; F468-P470 WeakPolarHBondContact O-CD 3.36Å; F468-E488 HydrophobicContact CE1-CB 4.17Å; F468-E488 HydrophobicContact CZ-CB 4.45Å; F468-V489 HydrophobicContact CD2-CG2 3.81Å; F468-V489 HydrophobicContact CE2-CB 4.48Å; F468-V489 HydrophobicContact CE2-CG2 3.73Å; F468-W492 HydrophobicContact CE2-CB 4.44Å; F468-W492 HydrophobicContact CZ-CB 4.17Å
469R95.1Very high96.2Very high165 Ų16568.4 Ų68.462%0.62336%0.362SS*.PPolyproline II helixtrans-68123.7173.2-171.2176.4-179.8-166.4-4.7109.2E472 K485R469-E472 IonicContact CZ-OE1 3.92Å; R469-E472 IonicContact CZ-OE2 2.77Å; R469-E472 IonicContact NE-OE1 2.66Å; R469-E472 PolarHBondContact NE-OE1 3.34Å; R469-E472 IonicContact NE-OE2 3.58Å; R469-E472 VanDerWaalsContact NH2-CD 3.33Å; R469-E472 IonicContact NH2-OE1 3.35Å; R469-E472 PolarHBondContact NH2-OE1 3.19Å; R469-E472 IonicContact NH2-OE2 3.68Å; R469-E472 PolarHBondContact NH2-OE2 2.89Å; R469-K485 PolarHBondContact O-NZ 2.86Å
470P96.6Very high96.3Very high47 Ų4768.6 Ų68.631%0.30537%0.369SS..PPolyproline II helixtrans-68.1168.917529.6-35.5000111.3F468 E472F468-P470 WeakPolarHBondContact O-CD 3.36Å; P470-E472 PolarHBondContact O-N 3.13Å
471I96.4Very high96.5Very high1 Ų168.8 Ų68.81%0.00536%0.362CS..PPolyproline II helixtrans-73123.8162.8-64.3177.5000107.1I452 L477 E481 V482 K485 R555I452-I471 HydrophobicContact CG1-CD1 4.17Å; I452-I471 PolarHBondContact O-N 3.4Å; I471-L477 HydrophobicContact CD1-CD2 3.94Å; I471-L477 HydrophobicContact CG2-CD2 4.01Å; I471-E481 HydrophobicContact CG1-CG 4.48Å; I471-V482 HydrophobicContact CD1-CG2 3.46Å; I471-V482 VanDerWaalsContact CD1-CG2 3.46Å; I471-K485 HydrophobicContact CD1-CD 4.26Å; I471-K485 HydrophobicContact CG1-CD 3.6Å; I471-R555 PolarHBondContact O-NH1 2.93Å; I471-R555 PolarHBondContact O-NH2 3.44Å
472E93.7Very high96.6Very high113 Ų11364.5 Ų64.553%0.52834%0.343SS..  trans-98.6-21.9-175.3-71.8170.2-168.200113.1R469 P470R469-E472 IonicContact CZ-OE1 3.92Å; R469-E472 IonicContact CZ-OE2 2.77Å; R469-E472 IonicContact NE-OE1 2.66Å; R469-E472 PolarHBondContact NE-OE1 3.34Å; R469-E472 IonicContact NE-OE2 3.58Å; R469-E472 VanDerWaalsContact NH2-CD 3.33Å; R469-E472 IonicContact NH2-OE1 3.35Å; R469-E472 PolarHBondContact NH2-OE1 3.19Å; R469-E472 IonicContact NH2-OE2 3.68Å; R469-E472 PolarHBondContact NH2-OE2 2.89Å; P470-E472 PolarHBondContact O-N 3.13Å
473S91.8Very high96.6Very high50 Ų5063.7 Ų63.735%0.3533%0.332SS..  trans-66.6145.4-179.1-1670000111.7D475 R555S473-D475 WeakPolarHBondContact OG-CB 3.36Å; S473-D475 PolarHBondContact OG-N 3.39Å; S473-D475 VanDerWaalsContact OG-N 3.13Å; S473-R555 PolarHBondContact O-NH2 3.06Å
474D89.5Confident96.6Very high113 Ų11362.3 Ų62.360%0.60434%0.335SS*.SBendtrans-98.9-2.1168-66.1-33.1000111.9R555D474-R555 IonicContact OD1-NE 3.48Å; D474-R555 PolarHBondContact OD1-NE 2.72Å
475D95.6Very high96.7Very high118 Ų11862.7 Ų62.763%0.63134%0.335SS*.SBendtrans-70.5177.4169.2-70.8-42.5000110.9S473 L477 P553S473-D475 WeakPolarHBondContact OG-CB 3.36Å; S473-D475 PolarHBondContact OG-N 3.39Å; S473-D475 VanDerWaalsContact OG-N 3.13Å; D475-L477 PolarHBondContact O-N 3.47Å; D475-P553 VanDerWaalsContact O-CD 3.28Å; D475-P553 WeakPolarHBondContact O-CD 3.08Å
476A97.3Very high96.7Very high35 Ų3562.3 Ų62.329%0.28933%0.332SS..SBendtrans-56.2137.2173.500000110.4D478 K550 V551 F552A476-D478 PolarHBondContact O-N 3.36Å; A476-K550 HydrophobicContact CB-CB 4.04Å; A476-K550 HydrophobicContact CB-CG 4.46Å; A476-V551 CarbonylContact C-O 3.59Å; A476-V551 VanDerWaalsContact CA-O 3.27Å; A476-V551 WeakPolarHBondContact CA-O 3.46Å; A476-F552 HydrophobicContact CB-CD1 4.23Å; A476-F552 HydrophobicContact CB-CE1 3.94Å; A476-F552 HydrophobicContact CB-CE2 4.49Å; A476-F552 HydrophobicContact CB-CZ 4.08Å
477L98.4Very high96.7Very high9 Ų962.9 Ų62.95%0.04733%0.332CS..PPolyproline II helixtrans-54.1128.4176.6-65.6-179.1000109.8I452 I471 D475 V482 I546 V551 P553 F564I452-L477 HydrophobicContact CD1-CD1 4.1Å; I471-L477 HydrophobicContact CD1-CD2 3.94Å; I471-L477 HydrophobicContact CG2-CD2 4.01Å; D475-L477 PolarHBondContact O-N 3.47Å; L477-V482 HydrophobicContact CB-CG2 4.06Å; L477-V482 HydrophobicContact CD1-CG2 4.41Å; L477-I546 HydrophobicContact CB-CG1 4.32Å; L477-I546 HydrophobicContact CB-CG2 3.99Å; L477-I546 HydrophobicContact CD1-CD1 3.9Å; L477-I546 HydrophobicContact CD1-CG1 4.07Å; L477-V551 HydrophobicContact CD1-CB 4.45Å; L477-V551 HydrophobicContact CD1-CG1 4.16Å; L477-V551 PolarHBondContact N-O 2.89Å; L477-P553 HydrophobicContact CD2-CB 4.33Å; L477-P553 HydrophobicContact CD2-CG 4.06Å; L477-F564 HydrophobicContact CD1-CD1 4.27Å; L477-F564 HydrophobicContact CD1-CE1 3.9Å
478D98.3Very high96.8Very high87 Ų8761 Ų6147%0.46532%0.319SS..PPolyproline II helixtrans-81.2128.9174.1180-97.4000110A476 D480 E481 V482A476-D478 PolarHBondContact O-N 3.36Å; D478-D480 PolarHBondContact O-N 3.05Å; D478-D480 PolarHBondContact OD1-N 2.89Å; D478-D480 VanDerWaalsContact OD1-N 3.11Å; D478-E481 HydrophobicContact CB-CB 4.04Å; D478-E481 PolarHBondContact O-N 2.79Å; D478-E481 PolarHBondContact OD1-N 2.92Å; D478-V482 VanDerWaalsContact O-CG2 3.29Å; D478-V482 WeakPolarHBondContact O-CG2 3.31Å; D478-V482 PolarHBondContact O-N 2.97Å
479F98.5Very high96.9Very high32 Ų3259 Ų5914%0.1431%0.31CS..Hα-helixtrans-61.8-44.2-176.2176.6-100.6000112.2V482 M483 L543 I546 K547 L583F479-V482 PolarHBondContact O-N 3.32Å; F479-M483 HydrophobicContact CD1-CG 4.12Å; F479-M483 HydrophobicContact CD2-CG 4.11Å; F479-M483 HydrophobicContact CE1-CG 3.72Å; F479-M483 HydrophobicContact CE2-CG 3.71Å; F479-M483 HydrophobicContact CE2-SD 3.93Å; F479-M483 HydrophobicContact CG-CG 4.31Å; F479-M483 HydrophobicContact CZ-CE 4.15Å; F479-M483 HydrophobicContact CZ-CG 3.49Å; F479-M483 VanDerWaalsContact CZ-CG 3.49Å; F479-M483 HydrophobicContact CZ-SD 3.76Å; F479-M483 VanDerWaalsContact O-CB 3.32Å; F479-M483 WeakPolarHBondContact O-CB 3.5Å; F479-M483 WeakPolarHBondContact O-CG 3.39Å; F479-M483 PolarHBondContact O-N 2.83Å; F479-L543 HydrophobicContact CE2-CB 4.28Å; F479-I546 HydrophobicContact CB-CG2 4.12Å; F479-I546 HydrophobicContact CD2-CG2 4.4Å; F479-K547 HydrophobicContact CB-CB 4.48Å; F479-K547 HydrophobicContact CD1-CD 4.22Å; F479-K547 HydrophobicContact CD1-CG 4.29Å; F479-K547 HydrophobicContact CD2-CB 3.55Å; F479-K547 HydrophobicContact CD2-CD 4.11Å; F479-K547 HydrophobicContact CD2-CG 3.98Å; F479-K547 HydrophobicContact CE1-CD 3.96Å; F479-K547 HydrophobicContact CE2-CB 3.92Å; F479-K547 HydrophobicContact CE2-CD 3.84Å; F479-K547 HydrophobicContact CE2-CG 4.23Å; F479-K547 HydrophobicContact CG-CB 4Å; F479-K547 HydrophobicContact CG-CD 4.29Å; F479-K547 HydrophobicContact CG-CG 4.01Å; F479-K547 HydrophobicContact CZ-CD 3.77Å; F479-L583 HydrophobicContact CE2-CD2 4.24Å; F479-L583 HydrophobicContact CZ-CD2 3.96Å
480D98.4Very high97.1Very high118 Ų11851.2 Ų51.263%0.63128%0.28SS*.Hα-helixtrans-70.5-38-176.5-66.9-29000110.9D478 A484D478-D480 PolarHBondContact O-N 3.05Å; D478-D480 PolarHBondContact OD1-N 2.89Å; D478-D480 VanDerWaalsContact OD1-N 3.11Å; D480-A484 WeakPolarHBondContact O-CB 3.11Å; D480-A484 PolarHBondContact O-N 3.11Å
481E98.5Very high97.2Very high74 Ų7451.2 Ų51.235%0.34628%0.277SS..Hα-helixtrans-63.1-47.6173.1-174.4178.1-168.100112I471 D478 M483 A484 K485I471-E481 HydrophobicContact CG1-CG 4.48Å; D478-E481 HydrophobicContact CB-CB 4.04Å; D478-E481 PolarHBondContact O-N 2.79Å; D478-E481 PolarHBondContact OD1-N 2.92Å; E481-M483 VanDerWaalsContact C-N 3.34Å; E481-M483 PolarHBondContact O-N 3.4Å; E481-A484 PolarHBondContact O-N 3.31Å; E481-K485 HydrophobicContact CG-CD 4.27Å; E481-K485 WeakPolarHBondContact O-CG 3.09Å; E481-K485 PolarHBondContact O-N 3.47Å; E481-K485 VanDerWaalsContact O-N 3.09Å; E481-K485 WeakPolarHBondContact OE1-CE 3.35Å; E481-K485 IonicContact OE1-NZ 3.45Å
482V98.6Very high97.3Very high0 Ų053 Ų530%028%0.283CS..Hα-helixtrans-61.4-44.8178.1171.10000110.5L448 I471 L477 D478 F479 K485 Y486 L543 I546L448-V482 HydrophobicContact CD1-CG1 3.8Å; I471-V482 HydrophobicContact CD1-CG2 3.46Å; I471-V482 VanDerWaalsContact CD1-CG2 3.46Å; L477-V482 HydrophobicContact CB-CG2 4.06Å; L477-V482 HydrophobicContact CD1-CG2 4.41Å; D478-V482 VanDerWaalsContact O-CG2 3.29Å; D478-V482 WeakPolarHBondContact O-CG2 3.31Å; D478-V482 PolarHBondContact O-N 2.97Å; F479-V482 PolarHBondContact O-N 3.32Å; V482-K485 PolarHBondContact O-N 3.02Å; V482-Y486 WeakPolarHBondContact O-CB 3.3Å; V482-Y486 PolarHBondContact O-N 2.81Å; V482-L543 HydrophobicContact CG1-CD2 4.23Å; V482-I546 HydrophobicContact CG1-CD1 4.01Å; V482-I546 HydrophobicContact CG2-CD1 4.26Å; V482-I546 HydrophobicContact CG2-CG2 4.42Å
483M98.2Very high97.5Very high27 Ų2747.7 Ų47.713%0.13326%0.258CS..Hα-helixtrans-61.3-44.9179.3-74.7-71.3-69.100112F479 E481 Y486 D487 L543 W586F479-M483 HydrophobicContact CD1-CG 4.12Å; F479-M483 HydrophobicContact CD2-CG 4.11Å; F479-M483 HydrophobicContact CE1-CG 3.72Å; F479-M483 HydrophobicContact CE2-CG 3.71Å; F479-M483 HydrophobicContact CE2-SD 3.93Å; F479-M483 HydrophobicContact CG-CG 4.31Å; F479-M483 HydrophobicContact CZ-CE 4.15Å; F479-M483 HydrophobicContact CZ-CG 3.49Å; F479-M483 VanDerWaalsContact CZ-CG 3.49Å; F479-M483 HydrophobicContact CZ-SD 3.76Å; F479-M483 VanDerWaalsContact O-CB 3.32Å; F479-M483 WeakPolarHBondContact O-CB 3.5Å; F479-M483 WeakPolarHBondContact O-CG 3.39Å; F479-M483 PolarHBondContact O-N 2.83Å; E481-M483 VanDerWaalsContact C-N 3.34Å; E481-M483 PolarHBondContact O-N 3.4Å; M483-Y486 PolarHBondContact O-N 3.12Å; M483-D487 WeakPolarHBondContact O-CB 3.35Å; M483-D487 PolarHBondContact O-N 3.07Å; M483-L543 HydrophobicContact SD-CD1 3.89Å; M483-L543 HydrophobicContact SD-CD2 3.68Å; M483-L543 HydrophobicContact SD-CG 4.35Å; M483-W586 HydrophobicContact CE-CD2 3.63Å; M483-W586 HydrophobicContact CE-CE3 3.72Å; M483-W586 HydrophobicContact CE-CG 4.48Å; M483-W586 HydrophobicContact CE-CH2 3.42Å; M483-W586 VanDerWaalsContact CE-CH2 3.42Å; M483-W586 HydrophobicContact CE-CZ2 3.3Å; M483-W586 HydrophobicContact CE-CZ3 3.63Å; M483-W586 HydrophobicContact SD-CE3 4.42Å; M483-W586 HydrophobicContact SD-CH2 4.03Å; M483-W586 HydrophobicContact SD-CZ2 4.47Å; M483-W586 HydrophobicContact SD-CZ3 4Å
484A98.2Very high97.8Very high58 Ų5845.3 Ų45.348%0.47924%0.242SC..Hα-helixtrans-61.9-45.1178.200000112D480 E481 D487 E488D480-A484 WeakPolarHBondContact O-CB 3.11Å; D480-A484 PolarHBondContact O-N 3.11Å; E481-A484 PolarHBondContact O-N 3.31Å; A484-D487 PolarHBondContact O-N 3.18Å; A484-E488 PolarHBondContact O-N 3.38Å
485K98.4Very high98.3Very high28 Ų2840.1 Ų40.112%0.12222%0.215CC..Hα-helixtrans-67.7-37.6176.8-68.6177-176.1-67.30112.2A451 R469 I471 E481 V482 D487 E488 V489A451-K485 HydrophobicContact CB-CB 4.03Å; A451-K485 WeakPolarHBondContact O-CD 3.31Å; R469-K485 PolarHBondContact O-NZ 2.86Å; I471-K485 HydrophobicContact CD1-CD 4.26Å; I471-K485 HydrophobicContact CG1-CD 3.6Å; E481-K485 HydrophobicContact CG-CD 4.27Å; E481-K485 WeakPolarHBondContact O-CG 3.09Å; E481-K485 PolarHBondContact O-N 3.47Å; E481-K485 VanDerWaalsContact O-N 3.09Å; E481-K485 WeakPolarHBondContact OE1-CE 3.35Å; E481-K485 IonicContact OE1-NZ 3.45Å; V482-K485 PolarHBondContact O-N 3.02Å; K485-D487 VanDerWaalsContact C-N 3.34Å; K485-E488 PolarHBondContact O-N 3.1Å; K485-V489 WeakPolarHBondContact O-CG2 3.21Å; K485-V489 PolarHBondContact O-N 3.08Å; K485-V489 VanDerWaalsContact O-N 3.08Å
486Y98.5Very high98.4Very high0 Ų035.7 Ų35.70%019%0.191CC..Hα-helixtrans-66.5-39.4178.9-173.4-133.3000111.3L444 A447 L448 A451 V482 M483 E488 V489 L490 V539 W586L444-Y486 PolarHBondContact O-OH 3.45Å; A447-Y486 HydrophobicContact CB-CE2 3.95Å; L448-Y486 HydrophobicContact CB-CD2 4.06Å; L448-Y486 HydrophobicContact CB-CE2 3.81Å; L448-Y486 HydrophobicContact CD1-CD1 4.19Å; L448-Y486 HydrophobicContact CD1-CD2 3.87Å; L448-Y486 HydrophobicContact CD1-CE2 4.32Å; L448-Y486 HydrophobicContact CD1-CG 3.8Å; L448-Y486 VanDerWaalsContact N-CE2 3.35Å; A451-Y486 HydrophobicContact CB-CD2 4.25Å; V482-Y486 WeakPolarHBondContact O-CB 3.3Å; V482-Y486 PolarHBondContact O-N 2.81Å; M483-Y486 PolarHBondContact O-N 3.12Å; Y486-E488 VanDerWaalsContact C-N 3.34Å; Y486-E488 PolarHBondContact O-N 2.78Å; Y486-V489 PolarHBondContact O-N 3.24Å; Y486-L490 HydrophobicContact CD1-CD1 4.04Å; Y486-L490 HydrophobicContact CD1-CG 4.4Å; Y486-L490 HydrophobicContact CD2-CD2 4.47Å; Y486-L490 HydrophobicContact CD2-CG 4.14Å; Y486-L490 HydrophobicContact CE1-CD1 3.73Å; Y486-L490 HydrophobicContact CE1-CD2 4.39Å; Y486-L490 HydrophobicContact CE1-CG 4.15Å; Y486-L490 HydrophobicContact CE2-CD1 4.37Å; Y486-L490 HydrophobicContact CE2-CD2 3.74Å; Y486-L490 HydrophobicContact CE2-CG 3.87Å; Y486-L490 HydrophobicContact CG-CD1 4.49Å; Y486-L490 HydrophobicContact CG-CG 4.39Å; Y486-L490 WeakPolarHBondContact O-CB 3.3Å; Y486-L490 VanDerWaalsContact O-CG 3.31Å; Y486-L490 WeakPolarHBondContact O-CG 3.33Å; Y486-L490 PolarHBondContact O-N 2.54Å; Y486-V539 HydrophobicContact CE1-CG1 3.66Å; Y486-V539 WeakPolarHBondContact OH-CG1 3.44Å; Y486-W586 HydrophobicContact CD1-CH2 4.2Å; Y486-W586 HydrophobicContact CD1-CZ3 4.06Å; Y486-W586 HydrophobicContact CE1-CZ3 4.2Å
487D98.2Very high98.5Very high60 Ų6034 Ų3432%0.32118%0.177SC..Hα-helixtrans-57.9-42.9173.6-170.175.9000112.8M483 A484 K485 L490 E491 K594M483-D487 WeakPolarHBondContact O-CB 3.35Å; M483-D487 PolarHBondContact O-N 3.07Å; A484-D487 PolarHBondContact O-N 3.18Å; K485-D487 VanDerWaalsContact C-N 3.34Å; D487-L490 PolarHBondContact O-N 3.4Å; D487-E491 PolarHBondContact O-N 3.46Å; D487-K594 WeakPolarHBondContact O-CE 3.39Å; D487-K594 PolarHBondContact O-NZ 3.45Å; D487-K594 WeakPolarHBondContact OD1-CE 3.41Å; D487-K594 IonicContact OD1-NZ 3.7Å; D487-K594 PolarHBondContact OD1-NZ 2.82Å; D487-K594 IonicContact OD2-NZ 2.67Å; D487-K594 PolarHBondContact OD2-NZ 3.46Å
488E98Very high98.5Very high104 Ų10433.6 Ų33.649%0.48618%0.175SC..Hα-helixtrans-63.4-43.5175.1-69.1-179.8177.700112.2F468 A484 K485 Y486 E491 W492F468-E488 HydrophobicContact CE1-CB 4.17Å; F468-E488 HydrophobicContact CZ-CB 4.45Å; A484-E488 PolarHBondContact O-N 3.38Å; K485-E488 PolarHBondContact O-N 3.1Å; Y486-E488 VanDerWaalsContact C-N 3.34Å; Y486-E488 PolarHBondContact O-N 2.78Å; E488-E491 WeakPolarHBondContact O-CB 3.2Å; E488-E491 PolarHBondContact O-N 2.77Å; E488-W492 PolarHBondContact O-N 2.89Å
489V98.7Very high98.5Very high1 Ų133.6 Ų33.61%0.00618%0.175CC..Hα-helixtrans-68.4-37.6177.6177.40000111.4A447 A451 F468 K485 Y486 E491 W492 L493A447-V489 HydrophobicContact CB-CG1 3.95Å; A447-V489 WeakPolarHBondContact O-CG1 3.48Å; A451-V489 HydrophobicContact CB-CB 4.39Å; A451-V489 HydrophobicContact CB-CG2 3.88Å; F468-V489 HydrophobicContact CD2-CG2 3.81Å; F468-V489 HydrophobicContact CE2-CB 4.48Å; F468-V489 HydrophobicContact CE2-CG2 3.73Å; K485-V489 WeakPolarHBondContact O-CG2 3.21Å; K485-V489 PolarHBondContact O-N 3.08Å; K485-V489 VanDerWaalsContact O-N 3.08Å; Y486-V489 PolarHBondContact O-N 3.24Å; V489-E491 VanDerWaalsContact C-N 3.3Å; V489-E491 PolarHBondContact O-N 3.06Å; V489-W492 HydrophobicContact CG1-CE3 4.14Å; V489-W492 HydrophobicContact CG1-CZ3 4.46Å; V489-W492 PolarHBondContact O-N 2.82Å; V489-L493 WeakPolarHBondContact O-CB 3.35Å; V489-L493 PolarHBondContact O-N 3.06Å
490L98.7Very high98.5Very high0 Ų032.2 Ų32.20%017%0.169CC..Hα-helixtrans-63.6-36.9175.6-73.7-176.8000111.7L444 A447 Y486 D487 L493 A494 T590 F591 K594L444-L490 HydrophobicContact CD2-CD2 4.28Å; L444-L490 HydrophobicContact CG-CD2 4.04Å; A447-L490 HydrophobicContact CB-CD2 4.48Å; Y486-L490 HydrophobicContact CD1-CD1 4.04Å; Y486-L490 HydrophobicContact CD1-CG 4.4Å; Y486-L490 HydrophobicContact CD2-CD2 4.47Å; Y486-L490 HydrophobicContact CD2-CG 4.14Å; Y486-L490 HydrophobicContact CE1-CD1 3.73Å; Y486-L490 HydrophobicContact CE1-CD2 4.39Å; Y486-L490 HydrophobicContact CE1-CG 4.15Å; Y486-L490 HydrophobicContact CE2-CD1 4.37Å; Y486-L490 HydrophobicContact CE2-CD2 3.74Å; Y486-L490 HydrophobicContact CE2-CG 3.87Å; Y486-L490 HydrophobicContact CG-CD1 4.49Å; Y486-L490 HydrophobicContact CG-CG 4.39Å; Y486-L490 WeakPolarHBondContact O-CB 3.3Å; Y486-L490 VanDerWaalsContact O-CG 3.31Å; Y486-L490 WeakPolarHBondContact O-CG 3.33Å; Y486-L490 PolarHBondContact O-N 2.54Å; D487-L490 PolarHBondContact O-N 3.4Å; L490-L493 PolarHBondContact O-N 3.3Å; L490-A494 WeakPolarHBondContact O-CB 3.45Å; L490-A494 PolarHBondContact O-N 2.91Å; L490-T590 HydrophobicContact CD1-CG2 4.25Å; L490-F591 HydrophobicContact CB-CD2 4.45Å; L490-F591 HydrophobicContact CD2-CD2 3.88Å; L490-F591 HydrophobicContact CD2-CE2 4.25Å; L490-K594 HydrophobicContact CB-CD 3.54Å
491E98.5Very high98.5Very high48 Ų4826.6 Ų26.622%0.22414%0.139CC..Hα-helixtrans-62.3-48.4175.7-177.261.6-141.400110.3D487 E488 V489 L493 A494 G495 K594 H597 Y598D487-E491 PolarHBondContact O-N 3.46Å; E488-E491 WeakPolarHBondContact O-CB 3.2Å; E488-E491 PolarHBondContact O-N 2.77Å; V489-E491 VanDerWaalsContact C-N 3.3Å; V489-E491 PolarHBondContact O-N 3.06Å; E491-L493 PolarHBondContact O-N 2.89Å; E491-A494 PolarHBondContact O-N 3.31Å; E491-G495 PolarHBondContact O-N 2.85Å; E491-G495 VanDerWaalsContact O-N 3.13Å; E491-K594 HydrophobicContact CB-CD 4.47Å; E491-K594 WeakPolarHBondContact OE2-CG 3.38Å; E491-K594 IonicContact OE2-NZ 3.43Å; E491-H597 IonicContact OE1-ND1 3.41Å; E491-H597 PolarHBondContact OE1-ND1 3.47Å; E491-H597 IonicContact OE2-CE1 3.4Å; E491-H597 PolarHBondContact OE2-CE1 2.97Å; E491-H597 IonicContact OE2-ND1 2.69Å; E491-H597 PolarHBondContact OE2-ND1 3.23Å; E491-Y598 PolarHBondContact O-OH 3.24Å; E491-Y598 VanDerWaalsContact O-OH 3.06Å; E491-Y598 VanDerWaalsContact OE1-CE2 3.26Å; E491-Y598 WeakPolarHBondContact OE1-CE2 3Å; E491-Y598 VanDerWaalsContact OE1-CZ 3.28Å; E491-Y598 PolarHBondContact OE1-OH 2.92Å
492W98.6Very high98.6Very high39 Ų3924.2 Ų24.215%0.14813%0.129CC..Hα-helixtrans-60.7-43.5174.6164.876.2000112.4I175 Y450 P466 F468 E488 V489 A494 G495 M496I175-W492 HydrophobicContact CD1-CH2 4.08Å; I175-W492 HydrophobicContact CD1-CZ3 3.67Å; I175-W492 HydrophobicContact CG2-CH2 4.19Å; Y450-W492 HydrophobicContact CD2-CH2 4.38Å; Y450-W492 HydrophobicContact CD2-CZ3 4.13Å; Y450-W492 HydrophobicContact CE2-CH2 4.29Å; Y450-W492 HydrophobicContact CE2-CZ3 4.46Å; P466-W492 VanDerWaalsContact CD-CD1 3.49Å; P466-W492 HydrophobicContact CG-CB 4.24Å; P466-W492 VanDerWaalsContact CG-CD1 3.45Å; P466-W492 HydrophobicContact CG-CD2 4.28Å; P466-W492 HydrophobicContact CG-CG 3.71Å; F468-W492 HydrophobicContact CE2-CB 4.44Å; F468-W492 HydrophobicContact CZ-CB 4.17Å; E488-W492 PolarHBondContact O-N 2.89Å; V489-W492 HydrophobicContact CG1-CE3 4.14Å; V489-W492 HydrophobicContact CG1-CZ3 4.46Å; V489-W492 PolarHBondContact O-N 2.82Å; W492-A494 PolarHBondContact O-N 2.92Å; W492-G495 PolarHBondContact O-N 2.84Å; W492-M496 HydrophobicContact CZ2-CE 4.15Å; W492-M496 HydrophobicContact CZ2-CG 4.36Å; W492-M496 WeakPolarHBondContact O-CB 3.44Å; W492-M496 PolarHBondContact O-N 3.13Å
493L98.8Very high98.6Very high0 Ų025.1 Ų25.10%014%0.136CC..Hα-helixtrans-62.9-43.3-179.8179.260.1000111.3I175 I176 A442 L444 A447 V489 L490 E491 G495 M496 Y497 F591I175-L493 HydrophobicContact CD1-CD1 4.47Å; I175-L493 HydrophobicContact CG1-CD1 3.98Å; I176-L493 HydrophobicContact CG2-CD1 3.81Å; A442-L493 HydrophobicContact CB-CD1 4.25Å; A442-L493 HydrophobicContact CB-CD2 4.12Å; A442-L493 HydrophobicContact CB-CG 4.33Å; L444-L493 HydrophobicContact CD1-CD2 4.12Å; A447-L493 HydrophobicContact CB-CD2 3.88Å; V489-L493 WeakPolarHBondContact O-CB 3.35Å; V489-L493 PolarHBondContact O-N 3.06Å; L490-L493 PolarHBondContact O-N 3.3Å; E491-L493 PolarHBondContact O-N 2.89Å; L493-G495 PolarHBondContact O-N 3.14Å; L493-M496 PolarHBondContact O-N 3.12Å; L493-Y497 WeakPolarHBondContact O-CB 3.18Å; L493-Y497 PolarHBondContact O-N 3.26Å; L493-F591 HydrophobicContact CD2-CE2 4.1Å; L493-F591 HydrophobicContact CD2-CZ 4.33Å; L493-F591 HydrophobicContact CG-CE2 4.2Å; L493-F591 HydrophobicContact CG-CZ 4.38Å
494A98.8Very high98.6Very high0 Ų023.9 Ų23.90%013%0.13CC..Hα-helixtrans-57.2-49.5175.400000110.7L490 E491 W492 M496 Y497 V498 F591 K594 L595 Y598L490-A494 WeakPolarHBondContact O-CB 3.45Å; L490-A494 PolarHBondContact O-N 2.91Å; E491-A494 PolarHBondContact O-N 3.31Å; W492-A494 PolarHBondContact O-N 2.92Å; A494-M496 PolarHBondContact O-N 3.18Å; A494-Y497 PolarHBondContact O-N 2.77Å; A494-V498 WeakPolarHBondContact O-CG2 3.28Å; A494-V498 PolarHBondContact O-N 3.4Å; A494-F591 HydrophobicContact CB-CE2 4.36Å; A494-K594 HydrophobicContact CB-CB 3.88Å; A494-L595 HydrophobicContact CB-CD2 3.97Å; A494-L595 HydrophobicContact CB-CG 4.33Å; A494-Y598 HydrophobicContact CB-CD2 4.19Å; A494-Y598 HydrophobicContact CB-CE2 3.87Å
495G98.5Very high98.6Very high5 Ų521.1 Ų21.15%0.05211%0.107CC..Hα-helixtrans-63-43.1177.200000113.8E491 W492 L493 Y497 N499E491-G495 PolarHBondContact O-N 2.85Å; E491-G495 VanDerWaalsContact O-N 3.13Å; W492-G495 PolarHBondContact O-N 2.84Å; L493-G495 PolarHBondContact O-N 3.14Å; G495-Y497 VanDerWaalsContact C-N 3.32Å; G495-Y497 PolarHBondContact O-N 2.8Å; G495-N499 VanDerWaalsContact O-CB 3.29Å; G495-N499 WeakPolarHBondContact O-CB 3.38Å; G495-N499 VanDerWaalsContact O-CG 3.29Å; G495-N499 PolarHBondContact O-N 2.96Å; G495-N499 PolarHBondContact O-ND2 2.9Å
496M98.6Very high98.6Very high24 Ų2423.9 Ų23.912%0.11812%0.118CC..Hα-helixtrans-61.5-42.6176.3-17756.564.800111.1E166 I167 A170 I176 W492 L493 A494 T500E166-M496 HydrophobicContact CB-CE 3.84Å; I167-M496 HydrophobicContact CB-SD 4.48Å; I167-M496 HydrophobicContact CG1-SD 3.76Å; A170-M496 HydrophobicContact CB-CG 4.09Å; A170-M496 HydrophobicContact CB-SD 4.33Å; I176-M496 HydrophobicContact CD1-CG 3.66Å; I176-M496 HydrophobicContact CD1-SD 4.38Å; I176-M496 HydrophobicContact CG1-CG 4.33Å; W492-M496 HydrophobicContact CZ2-CE 4.15Å; W492-M496 HydrophobicContact CZ2-CG 4.36Å; W492-M496 WeakPolarHBondContact O-CB 3.44Å; W492-M496 PolarHBondContact O-N 3.13Å; L493-M496 PolarHBondContact O-N 3.12Å; A494-M496 PolarHBondContact O-N 3.18Å; M496-T500 WeakPolarHBondContact O-CB 3.47Å; M496-T500 PolarHBondContact O-N 3.02Å; M496-T500 VanDerWaalsContact O-N 3.13Å; M496-T500 PolarHBondContact O-OG1 3.08Å
497Y98.8Very high98.6Very high0 Ų024.8 Ų24.80%012%0.122CC..Hα-helixtrans-68.6-51.7-178.7-166.9-171.7000111.5I176 L179 G439 A440 R441 A442 L493 A494 G495 N499 T500 L501 T531 G532 F591I176-Y497 HydrophobicContact CG2-CD2 4.14Å; I176-Y497 HydrophobicContact CG2-CG 4.12Å; L179-Y497 HydrophobicContact CD1-CE2 4.18Å; L179-Y497 HydrophobicContact CD2-CD2 4.19Å; L179-Y497 HydrophobicContact CD2-CE2 4.07Å; L179-Y497 HydrophobicContact CG-CE2 4.17Å; G439-Y497 WeakPolarHBondContact O-CE2 3.23Å; G439-Y497 PolarHBondContact O-OH 3.43Å; A440-Y497 PolarHBondContact O-OH 2.73Å; R441-Y497 WeakPolarHBondContact CA-OH 3.41Å; R441-Y497 PolarHBondContact N-OH 3.04Å; R441-Y497 VanDerWaalsContact N-OH 3.08Å; A442-Y497 HydrophobicContact CB-CD1 3.71Å; A442-Y497 HydrophobicContact CB-CE1 3.74Å; A442-Y497 HydrophobicContact CB-CG 4.4Å; L493-Y497 WeakPolarHBondContact O-CB 3.18Å; L493-Y497 PolarHBondContact O-N 3.26Å; A494-Y497 PolarHBondContact O-N 2.77Å; G495-Y497 VanDerWaalsContact C-N 3.32Å; G495-Y497 PolarHBondContact O-N 2.8Å; Y497-N499 PolarHBondContact O-N 3.33Å; Y497-T500 PolarHBondContact O-N 3.28Å; Y497-L501 HydrophobicContact CD2-CD1 3.8Å; Y497-L501 HydrophobicContact CD2-CG 3.87Å; Y497-L501 HydrophobicContact CE2-CD1 3.51Å; Y497-L501 HydrophobicContact CE2-CD2 4.12Å; Y497-L501 HydrophobicContact CE2-CG 3.8Å; Y497-L501 WeakPolarHBondContact O-CG 3.34Å; Y497-L501 PolarHBondContact O-N 3.25Å; Y497-T531 HydrophobicContact CD1-CG2 4.09Å; Y497-T531 HydrophobicContact CE1-CG2 3.92Å; Y497-G532 PolarHBondContact OH-N 3.07Å; Y497-F591 HydrophobicContact CD1-CZ 4.38Å
498V98.8Very high98.7Very high1 Ų122 Ų221%0.00611%0.107CC..Hα-helixtrans-61.3-45.1-179.3172.90000111.5A494 T500 L501 N502 F529 L595 Y598 H599 T600A494-V498 WeakPolarHBondContact O-CG2 3.28Å; A494-V498 PolarHBondContact O-N 3.4Å; V498-T500 VanDerWaalsContact C-N 3.32Å; V498-T500 PolarHBondContact O-N 2.63Å; V498-L501 PolarHBondContact O-N 2.94Å; V498-N502 WeakPolarHBondContact O-CB 3.18Å; V498-N502 VanDerWaalsContact O-CG 3.26Å; V498-N502 PolarHBondContact O-N 3.09Å; V498-N502 PolarHBondContact O-ND2 3.05Å; V498-F529 HydrophobicContact CB-CE1 4.34Å; V498-F529 HydrophobicContact CG1-CE1 4.06Å; V498-F529 HydrophobicContact CG1-CZ 4.29Å; V498-F529 HydrophobicContact CG2-CE1 4.27Å; V498-L595 HydrophobicContact CG2-CD2 3.8Å; V498-Y598 HydrophobicContact CB-CG 4.48Å; V498-H599 WeakPolarHBondContact CG1-O 3.37Å; V498-T600 HydrophobicContact CG1-CG2 4.15Å
499N98.4Very high98.7Very high87 Ų8717.7 Ų17.747%0.4659%0.087SC..Hα-helixtrans-65.4-35.9178.7-72.7-45.8000112.7G495 Y497 N502 A503G495-N499 VanDerWaalsContact O-CB 3.29Å; G495-N499 WeakPolarHBondContact O-CB 3.38Å; G495-N499 VanDerWaalsContact O-CG 3.29Å; G495-N499 PolarHBondContact O-N 2.96Å; G495-N499 PolarHBondContact O-ND2 2.9Å; Y497-N499 PolarHBondContact O-N 3.33Å; N499-N502 PolarHBondContact O-N 2.79Å; N499-A503 PolarHBondContact O-N 3.42Å
500T98.8Very high98.7Very high2 Ų223.3 Ų23.31%0.01211%0.112CC..Hα-helixtrans-64.2-44.9174.5-57.90000111Y163 I167 I176 L179 M496 Y497 V498 A503 I504Y163-T500 HydrophobicContact CE1-CG2 3.86Å; Y163-T500 VanDerWaalsContact OH-CG2 3.3Å; Y163-T500 WeakPolarHBondContact OH-CG2 3.28Å; I167-T500 WeakPolarHBondContact CG1-OG1 3.36Å; I167-T500 HydrophobicContact CG2-CG2 3.71Å; I176-T500 HydrophobicContact CD1-CG2 4.35Å; I176-T500 WeakPolarHBondContact CD1-OG1 3.32Å; L179-T500 HydrophobicContact CD2-CG2 3.49Å; L179-T500 VanDerWaalsContact CD2-CG2 3.49Å; M496-T500 WeakPolarHBondContact O-CB 3.47Å; M496-T500 PolarHBondContact O-N 3.02Å; M496-T500 VanDerWaalsContact O-N 3.13Å; M496-T500 PolarHBondContact O-OG1 3.08Å; Y497-T500 PolarHBondContact O-N 3.28Å; V498-T500 VanDerWaalsContact C-N 3.32Å; V498-T500 PolarHBondContact O-N 2.63Å; T500-A503 PolarHBondContact O-N 2.87Å; T500-I504 HydrophobicContact CG2-CD1 4.41Å; T500-I504 WeakPolarHBondContact O-CG1 3.01Å; T500-I504 PolarHBondContact O-N 3.15Å; T500-I504 VanDerWaalsContact O-N 3.13Å
501L98.8Very high98.6Very high0 Ų025.8 Ų25.80%012%0.121CC..Hα-helixtrans-68.5-35.2178.4-69.2-176.7000112.8L179 G439 Y497 V498 A503 I504 H505 F529 T531L179-L501 HydrophobicContact CD2-CD2 3.65Å; L179-L501 HydrophobicContact CD2-CG 4.27Å; L179-L501 HydrophobicContact CG-CD2 3.92Å; G439-L501 VanDerWaalsContact CA-CD1 3.5Å; Y497-L501 HydrophobicContact CD2-CD1 3.8Å; Y497-L501 HydrophobicContact CD2-CG 3.87Å; Y497-L501 HydrophobicContact CE2-CD1 3.51Å; Y497-L501 HydrophobicContact CE2-CD2 4.12Å; Y497-L501 HydrophobicContact CE2-CG 3.8Å; Y497-L501 WeakPolarHBondContact O-CG 3.34Å; Y497-L501 PolarHBondContact O-N 3.25Å; V498-L501 PolarHBondContact O-N 2.94Å; L501-A503 VanDerWaalsContact C-N 3.28Å; L501-A503 PolarHBondContact O-N 3.18Å; L501-I504 HydrophobicContact CD2-CD1 4.09Å; L501-I504 PolarHBondContact O-N 3.34Å; L501-I504 VanDerWaalsContact O-N 3.1Å; L501-H505 PolarHBondContact O-CD2 3.22Å; L501-H505 PolarHBondContact O-N 3.32Å; L501-F529 HydrophobicContact CB-CE1 3.5Å; L501-F529 VanDerWaalsContact CB-CE1 3.5Å; L501-F529 HydrophobicContact CB-CE2 4.15Å; L501-F529 HydrophobicContact CB-CZ 3.21Å; L501-F529 HydrophobicContact CD1-CD1 4.24Å; L501-F529 HydrophobicContact CD1-CE1 3.62Å; L501-F529 HydrophobicContact CD1-CZ 4.2Å; L501-F529 HydrophobicContact CG-CE1 4.2Å; L501-F529 HydrophobicContact CG-CZ 4.35Å; L501-T531 HydrophobicContact CD1-CG2 4.02Å
502N98.8Very high98.6Very high24 Ų2423.9 Ų23.913%0.12811%0.112CC..Hα-helixtrans-56.2-44.9173-76.9-20.5000111.3V498 N499 Y506 F529 H599 T600 Y601V498-N502 WeakPolarHBondContact O-CB 3.18Å; V498-N502 VanDerWaalsContact O-CG 3.26Å; V498-N502 PolarHBondContact O-N 3.09Å; V498-N502 PolarHBondContact O-ND2 3.05Å; N499-N502 PolarHBondContact O-N 2.79Å; N502-Y506 VanDerWaalsContact O-CB 3.27Å; N502-Y506 WeakPolarHBondContact O-CB 3.47Å; N502-Y506 PolarHBondContact O-N 3.24Å; N502-Y506 VanDerWaalsContact O-N 3.13Å; N502-F529 WeakPolarHBondContact OD1-CE2 3.06Å; N502-F529 VanDerWaalsContact OD1-CZ 3.32Å; N502-F529 WeakPolarHBondContact OD1-CZ 3.31Å; N502-H599 PolarHBondContact ND2-O 3.06Å; N502-T600 WeakPolarHBondContact OD1-CA 3.4Å; N502-Y601 WeakPolarHBondContact OD1-CB 3.5Å; N502-Y601 PolarHBondContact OD1-N 3.49Å
503A98.7Very high98.6Very high20 Ų2023.5 Ų23.517%0.16511%0.111CC..Hα-helixtrans-63.4-43.7175.200000111.9V162 Y163 N499 T500 L501 M507V162-A503 HydrophobicContact CG2-CB 3.92Å; Y163-A503 HydrophobicContact CD1-CB 4.43Å; Y163-A503 HydrophobicContact CE1-CB 4.24Å; N499-A503 PolarHBondContact O-N 3.42Å; T500-A503 PolarHBondContact O-N 2.87Å; L501-A503 VanDerWaalsContact C-N 3.28Å; L501-A503 PolarHBondContact O-N 3.18Å; A503-M507 VanDerWaalsContact O-CG 3.23Å; A503-M507 WeakPolarHBondContact O-CG 3.32Å; A503-M507 PolarHBondContact O-N 3.12Å
504I98.9Very high98.6Very high0 Ų023.6 Ų23.60%011%0.111CC..Hα-helixtrans-61.7-53.7179.3-67.2176.9000111.4H155 V159 Y163 L179 P180 D181 T500 L501 Y506 M507 H508H155-I504 PolarHBondContact CE1-O 3.22Å; V159-I504 HydrophobicContact CG1-CG1 3.96Å; V159-I504 HydrophobicContact CG2-CG1 4.34Å; Y163-I504 HydrophobicContact CE1-CG1 4.35Å; Y163-I504 VanDerWaalsContact OH-CD1 3.24Å; Y163-I504 WeakPolarHBondContact OH-CD1 3.3Å; Y163-I504 WeakPolarHBondContact OH-CG1 3.4Å; L179-I504 HydrophobicContact CB-CD1 3.61Å; L179-I504 HydrophobicContact CD2-CD1 3.98Å; L179-I504 HydrophobicContact CG-CD1 4.33Å; P180-I504 HydrophobicContact CB-CG2 4.45Å; P180-I504 HydrophobicContact CG-CG2 3.99Å; P180-I504 VanDerWaalsContact O-CG2 3.3Å; P180-I504 WeakPolarHBondContact O-CG2 3.43Å; D181-I504 HydrophobicContact CB-CD1 4.16Å; D181-I504 HydrophobicContact CB-CG1 4.41Å; T500-I504 HydrophobicContact CG2-CD1 4.41Å; T500-I504 WeakPolarHBondContact O-CG1 3.01Å; T500-I504 PolarHBondContact O-N 3.15Å; T500-I504 VanDerWaalsContact O-N 3.13Å; L501-I504 HydrophobicContact CD2-CD1 4.09Å; L501-I504 PolarHBondContact O-N 3.34Å; L501-I504 VanDerWaalsContact O-N 3.1Å; I504-Y506 PolarHBondContact O-N 3.42Å; I504-M507 PolarHBondContact O-N 3.37Å; I504-H508 WeakPolarHBondContact O-CB 3.31Å; I504-H508 PolarHBondContact O-N 2.92Å
505H98.9Very high98.6Very high0 Ų023.9 Ų23.90%011%0.114CC..Hα-helixtrans-70.8-33.3-172.8-62.2-54.4000112.8F437 F438 L501 M507 H508 D509 F529 Y601F437-H505 VanDerWaalsContact C-CE1 3.5Å; F437-H505 HydrophobicContact CD1-CB 4.08Å; F437-H505 AromaticContact CD1-CG 3.88Å; F437-H505 AromaticContact CD1-ND1 3.78Å; F437-H505 HydrophobicContact CD2-CB 4.19Å; F437-H505 HydrophobicContact CE1-CB 4.28Å; F437-H505 HydrophobicContact CE2-CB 4.34Å; F437-H505 HydrophobicContact CG-CB 4.04Å; F437-H505 AromaticContact CG-CD2 3.98Å; F437-H505 AromaticContact CG-CG 3.67Å; F437-H505 AromaticContact CG-ND1 3.87Å; F437-H505 HydrophobicContact CZ-CB 4.37Å; F438-H505 PolarHBondContact N-CE1 3.36Å; F438-H505 PolarHBondContact O-CE1 2.99Å; F438-H505 PolarHBondContact O-NE2 3.04Å; L501-H505 PolarHBondContact O-CD2 3.22Å; L501-H505 PolarHBondContact O-N 3.32Å; H505-M507 VanDerWaalsContact C-N 3.34Å; H505-H508 PolarHBondContact O-N 3.13Å; H505-D509 PolarHBondContact O-N 3.1Å; H505-F529 AromaticContact CD2-CE2 3.74Å; H505-Y601 HydrophobicContact CB-CD1 3.63Å; H505-Y601 HydrophobicContact CB-CE1 4.14Å
506Y98.7Very high98.6Very high87 Ų8723.6 Ų23.634%0.34111%0.111SC..Hα-helixtrans-58.7-47170.1-178.9-81.1000111.3N502 I504 K510 Y601N502-Y506 VanDerWaalsContact O-CB 3.27Å; N502-Y506 WeakPolarHBondContact O-CB 3.47Å; N502-Y506 PolarHBondContact O-N 3.24Å; N502-Y506 VanDerWaalsContact O-N 3.13Å; I504-Y506 PolarHBondContact O-N 3.42Å; Y506-K510 HydrophobicContact CE1-CD 4.05Å; Y506-K510 WeakPolarHBondContact O-CB 3.27Å; Y506-K510 PolarHBondContact O-N 2.8Å; Y506-Y601 HydrophobicContact CD2-CD2 4.09Å; Y506-Y601 AromaticContact CD2-CE2 3.53Å; Y506-Y601 HydrophobicContact CD2-CE2 3.53Å; Y506-Y601 HydrophobicContact CE2-CE2 4.46Å; Y506-Y601 HydrophobicContact CG-CE2 4.19Å
507M98.7Very high98.6Very high19 Ų1922.5 Ų22.59%0.09411%0.106CC..Hα-helixtrans-72.4-32.9-179.1-64-55.9175.500112.4A158 V159 V162 A503 I504 H505 K510 Y511A158-M507 HydrophobicContact CB-CB 4.08Å; A158-M507 HydrophobicContact CB-CG 3.96Å; A158-M507 HydrophobicContact CB-SD 3.69Å; V159-M507 HydrophobicContact CG2-CB 3.65Å; V159-M507 HydrophobicContact CG2-CG 4.04Å; V162-M507 HydrophobicContact CB-CE 4.12Å; V162-M507 HydrophobicContact CG1-CE 3.36Å; V162-M507 HydrophobicContact CG2-CE 3.64Å; A503-M507 VanDerWaalsContact O-CG 3.23Å; A503-M507 WeakPolarHBondContact O-CG 3.32Å; A503-M507 PolarHBondContact O-N 3.12Å; I504-M507 PolarHBondContact O-N 3.37Å; H505-M507 VanDerWaalsContact C-N 3.34Å; M507-K510 PolarHBondContact O-N 2.92Å; M507-Y511 HydrophobicContact CB-CD2 4.35Å; M507-Y511 VanDerWaalsContact O-CD2 3.3Å; M507-Y511 WeakPolarHBondContact O-CD2 3.48Å; M507-Y511 PolarHBondContact O-N 3.3Å; M507-Y511 HydrophobicContact SD-CD2 4.3Å; M507-Y511 HydrophobicContact SD-CE2 3.73Å
508H98.8Very high98.6Very high0 Ų022.5 Ų22.50%011%0.106CC..Hα-helixtrans-67.3-45.9177.4-156-62.2000111.4H155 G184 R185 I504 H505 K510 Y511 Y512 Y513 E514H155-H508 AromaticContact CD2-CD2 3.79Å; H155-H508 AromaticContact CE1-CD2 3.8Å; H155-H508 WeakPolarHBondContact ND1-CA 3.4Å; H155-H508 PolarHBondContact ND1-N 3.3Å; H155-H508 AromaticContact NE2-CD2 3.62Å; G184-H508 WeakPolarHBondContact CA-NE2 3.5Å; R185-H508 PolarHBondContact N-NE2 2.9Å; I504-H508 WeakPolarHBondContact O-CB 3.31Å; I504-H508 PolarHBondContact O-N 2.92Å; H505-H508 PolarHBondContact O-N 3.13Å; H508-K510 PolarHBondContact O-N 2.85Å; H508-Y511 PolarHBondContact O-N 3.05Å; H508-Y512 AromaticContact CE1-CD1 3.67Å; H508-Y512 AromaticContact CE1-CG 3.99Å; H508-Y512 PolarHBondContact CE1-O 2.73Å; H508-Y512 PolarHBondContact ND1-O 3.43Å; H508-Y512 AromaticContact NE2-CD1 3.7Å; H508-Y512 CarbonylContact O-C 3.48Å; H508-Y512 WeakPolarHBondContact O-CA 3.46Å; H508-Y512 PolarHBondContact O-N 3.14Å; H508-Y513 PolarHBondContact O-N 2.68Å; H508-E514 IonicContact CE1-OE1 3.7Å; H508-E514 PolarHBondContact CE1-OE1 3.38Å; H508-E514 IonicContact ND1-OE1 3.69Å; H508-E514 PolarHBondContact ND1-OE1 3.04Å; H508-E514 IonicContact NE2-OE1 3.45Å
509D98.6Very high98.6Very high14 Ų1422.6 Ų22.68%0.07511%0.107CC..Hα-helixtrans-58.1-35.8173.4-83.55.7000111.5R185 H505 Y601 R602R185-D509 IonicContact CZ-OD1 3.09Å; R185-D509 VanDerWaalsContact CZ-OD1 3.23Å; R185-D509 IonicContact NH1-OD1 3.95Å; R185-D509 PolarHBondContact NH1-OD1 2.65Å; R185-D509 IonicContact NH2-OD1 3.62Å; R185-D509 PolarHBondContact NH2-OD1 3.47Å; H505-D509 PolarHBondContact O-N 3.1Å; D509-Y601 VanDerWaalsContact OD2-CE1 3.25Å; D509-Y601 WeakPolarHBondContact OD2-CE1 3.42Å; D509-Y601 PolarHBondContact OD2-OH 3.06Å; D509-R602 WeakPolarHBondContact OD2-CD 3.34Å; D509-R602 IonicContact OD2-CZ 3.14Å; D509-R602 IonicContact OD2-NE 2.7Å; D509-R602 IonicContact OD2-NH1 3.04Å; D509-R602 PolarHBondContact OD2-NH1 3.46Å
510K98.1Very high98.6Very high120 Ų12018.4 Ų18.452%0.5228%0.084SC..Hα-helixtrans-79-36.4-175.5-174.1168.2-178.7168.20114.4Y506 M507 H508Y506-K510 HydrophobicContact CE1-CD 4.05Å; Y506-K510 WeakPolarHBondContact O-CB 3.27Å; Y506-K510 PolarHBondContact O-N 2.8Å; M507-K510 PolarHBondContact O-N 2.92Å; H508-K510 PolarHBondContact O-N 2.85Å
511Y98.2Very high98.6Very high51 Ų5118.3 Ų18.320%0.28%0.084CC..Hα-helixtrans-118.4-12.8-170-62.4-72.4000114.4K153 A158 M507 H508K153-Y511 HydrophobicContact CB-CD1 4.16Å; K153-Y511 HydrophobicContact CB-CE1 3.8Å; K153-Y511 HydrophobicContact CD-CE1 4.21Å; K153-Y511 HydrophobicContact CG-CE1 4.32Å; K153-Y511 VanDerWaalsContact O-CD1 3.29Å; K153-Y511 WeakPolarHBondContact O-CD1 3.32Å; A158-Y511 HydrophobicContact CB-CD2 3.36Å; A158-Y511 HydrophobicContact CB-CE2 3.18Å; A158-Y511 HydrophobicContact CB-CG 4.32Å; M507-Y511 HydrophobicContact CB-CD2 4.35Å; M507-Y511 VanDerWaalsContact O-CD2 3.3Å; M507-Y511 WeakPolarHBondContact O-CD2 3.48Å; M507-Y511 PolarHBondContact O-N 3.3Å; M507-Y511 HydrophobicContact SD-CD2 4.3Å; M507-Y511 HydrophobicContact SD-CE2 3.73Å; H508-Y511 PolarHBondContact O-N 3.05Å
512Y97.8Very high98.5Very high9 Ų920.5 Ų20.54%0.03510%0.096CC..SBendtrans-150.750.3-177.1-161.6-156.8000112.4Y123 E275 Q276 N277 H508Y123-Y512 HydrophobicContact CG-CD2 4.32Å; Y123-Y512 HydrophobicContact CG-CE2 4.42Å; E275-Y512 PolarHBondContact O-OH 3.24Å; Q276-Y512 VanDerWaalsContact OE1-CZ 3.23Å; N277-Y512 PolarHBondContact N-OH 3.11Å; N277-Y512 VanDerWaalsContact OD1-CE1 3.29Å; N277-Y512 WeakPolarHBondContact OD1-CE1 3.33Å; N277-Y512 PolarHBondContact OD1-OH 3.23Å; H508-Y512 AromaticContact CE1-CD1 3.67Å; H508-Y512 AromaticContact CE1-CG 3.99Å; H508-Y512 PolarHBondContact CE1-O 2.73Å; H508-Y512 PolarHBondContact ND1-O 3.43Å; H508-Y512 AromaticContact NE2-CD1 3.7Å; H508-Y512 CarbonylContact O-C 3.48Å; H508-Y512 WeakPolarHBondContact O-CA 3.46Å; H508-Y512 PolarHBondContact O-N 3.14Å
513Y98.5Very high98.4Very high31 Ų3120.2 Ų20.212%0.1229%0.094CC..  trans-65.2132.9178.9-175.7-103.8000112.7E229 Q233 Q276 H508 A515 L518E229-Y513 HydrophobicContact CB-CE1 4.03Å; E229-Y513 HydrophobicContact CB-CE2 4.23Å; E229-Y513 WeakPolarHBondContact CB-OH 3.24Å; E229-Y513 HydrophobicContact CG-CD2 4.17Å; E229-Y513 HydrophobicContact CG-CE1 4.09Å; E229-Y513 HydrophobicContact CG-CE2 3.59Å; Q233-Y513 HydrophobicContact CG-CE1 4.28Å; Q233-Y513 PolarHBondContact NE2-OH 2.9Å; Q276-Y513 PolarHBondContact NE2-O 3.28Å; H508-Y513 PolarHBondContact O-N 2.68Å; Y513-A515 HydrophobicContact CD1-CB 4.03Å; Y513-A515 HydrophobicContact CE1-CB 4.31Å; Y513-A515 PolarHBondContact O-N 3.48Å; Y513-L518 HydrophobicContact CD1-CD1 4.42Å; Y513-L518 HydrophobicContact CD2-CD1 3.9Å; Y513-L518 HydrophobicContact CE1-CB 4.41Å; Y513-L518 HydrophobicContact CE1-CD1 3.85Å; Y513-L518 HydrophobicContact CE2-CD1 3.26Å; Y513-L518 HydrophobicContact CG-CD1 4.43Å; Y513-L518 WeakPolarHBondContact OH-CD1 3.21Å
514E98.5Very high98.1Very high1 Ų125.7 Ų25.71%0.00512%0.121CC..  trans-82.258.8-173.4-56.190.2158.800113R185 I188 Q276 H508 A516 E517 L518R185-E514 VanDerWaalsContact CG-OE1 3.24Å; R185-E514 WeakPolarHBondContact CG-OE1 3.41Å; R185-E514 IonicContact CZ-OE1 3.06Å; R185-E514 IonicContact CZ-OE2 2.74Å; R185-E514 IonicContact NE-OE1 2.96Å; R185-E514 PolarHBondContact NE-OE1 2.98Å; R185-E514 IonicContact NE-OE2 3.96Å; R185-E514 IonicContact NH2-OE1 3.91Å; R185-E514 PolarHBondContact NH2-OE1 2.78Å; R185-E514 IonicContact NH2-OE2 2.78Å; R185-E514 PolarHBondContact NH2-OE2 3.45Å; I188-E514 HydrophobicContact CD1-CB 3.84Å; I188-E514 HydrophobicContact CD1-CG 3.68Å; Q276-E514 HydrophobicContact CG-CB 4.02Å; Q276-E514 HydrophobicContact CG-CG 3.81Å; H508-E514 IonicContact CE1-OE1 3.7Å; H508-E514 PolarHBondContact CE1-OE1 3.38Å; H508-E514 IonicContact ND1-OE1 3.69Å; H508-E514 PolarHBondContact ND1-OE1 3.04Å; H508-E514 IonicContact NE2-OE1 3.45Å; E514-A516 VanDerWaalsContact C-N 3.31Å; E514-A516 PolarHBondContact O-N 3.19Å; E514-E517 HydrophobicContact CB-CB 4.45Å; E514-E517 PolarHBondContact O-N 2.91Å; E514-E517 VanDerWaalsContact O-N 3.16Å; E514-L518 HydrophobicContact CB-CD1 4.14Å; E514-L518 HydrophobicContact CB-CG 4.36Å; E514-L518 WeakPolarHBondContact O-CB 3.31Å; E514-L518 WeakPolarHBondContact O-CG 3.21Å; E514-L518 PolarHBondContact O-N 2.83Å
515A98.6Very high97.9Very high6 Ų626.5 Ų26.55%0.0513%0.125CC..Hα-helixtrans-54.8-39.7-170.400000114.2D232 A236 Y513 A519D232-A515 HydrophobicContact CB-CB 4.27Å; A236-A515 HydrophobicContact CB-CB 3.87Å; Y513-A515 HydrophobicContact CD1-CB 4.03Å; Y513-A515 HydrophobicContact CE1-CB 4.31Å; Y513-A515 PolarHBondContact O-N 3.48Å; A515-A519 WeakPolarHBondContact O-CB 3.13Å; A515-A519 PolarHBondContact O-N 3.5Å
516A98.4Very high97.7Very high0 Ų030.7 Ų30.70%014%0.143CC..Hα-helixtrans-65.6-41-18000000113.2A236 A271 E514A236-A516 HydrophobicContact CB-CB 4.4Å; A271-A516 HydrophobicContact CB-CB 4.32Å; E514-A516 VanDerWaalsContact C-N 3.31Å; E514-A516 PolarHBondContact O-N 3.19Å
517E98.4Very high97.7Very high0 Ų027.9 Ų27.90%013%0.132CC..Hα-helixtrans-73.5-49.5178-66.6171.395.800110.5I188 A272 E514 A519 L520 M521I188-E517 HydrophobicContact CG2-CB 3.71Å; I188-E517 HydrophobicContact CG2-CG 4.5Å; A272-E517 HydrophobicContact CB-CG 3.39Å; E514-E517 HydrophobicContact CB-CB 4.45Å; E514-E517 PolarHBondContact O-N 2.91Å; E514-E517 VanDerWaalsContact O-N 3.16Å; E517-A519 PolarHBondContact O-N 3.29Å; E517-L520 WeakPolarHBondContact O-CB 3.41Å; E517-L520 PolarHBondContact O-N 3.42Å; E517-M521 WeakPolarHBondContact O-CG 3.5Å
518L98.6Very high97.7Very high0 Ų027.3 Ų27.30%013%0.13CC..Hα-helixtrans-68.4-22.8-176.4-63.4168.9000112.6I188 Q233 M435 Y513 E514 L520 M521 L525I188-L518 HydrophobicContact CD1-CD2 4.43Å; I188-L518 HydrophobicContact CG2-CD2 4.15Å; Q233-L518 HydrophobicContact CG-CB 4.4Å; M435-L518 HydrophobicContact SD-CD2 3.82Å; Y513-L518 HydrophobicContact CD1-CD1 4.42Å; Y513-L518 HydrophobicContact CD2-CD1 3.9Å; Y513-L518 HydrophobicContact CE1-CB 4.41Å; Y513-L518 HydrophobicContact CE1-CD1 3.85Å; Y513-L518 HydrophobicContact CE2-CD1 3.26Å; Y513-L518 HydrophobicContact CG-CD1 4.43Å; Y513-L518 WeakPolarHBondContact OH-CD1 3.21Å; E514-L518 HydrophobicContact CB-CD1 4.14Å; E514-L518 HydrophobicContact CB-CG 4.36Å; E514-L518 WeakPolarHBondContact O-CB 3.31Å; E514-L518 WeakPolarHBondContact O-CG 3.21Å; E514-L518 PolarHBondContact O-N 2.83Å; L518-L520 PolarHBondContact O-N 2.84Å; L518-M521 HydrophobicContact CD2-SD 3.8Å; L518-M521 PolarHBondContact O-N 2.84Å; L518-L525 HydrophobicContact CD2-CD1 3.57Å
519A98.6Very high97.6Very high3 Ų327.3 Ų27.33%0.02513%0.13CC..THydrogen-bonded Turntrans-65-24.7170.800000113.2K207 Q233 L237 A515 E517 M521K207-A519 WeakPolarHBondContact CE-O 3.33Å; Q233-A519 HydrophobicContact CB-CB 3.65Å; Q233-A519 HydrophobicContact CG-CB 4.04Å; L237-A519 HydrophobicContact CD1-CB 4.37Å; L237-A519 HydrophobicContact CD2-CB 3.97Å; L237-A519 HydrophobicContact CG-CB 3.82Å; A515-A519 WeakPolarHBondContact O-CB 3.13Å; A515-A519 PolarHBondContact O-N 3.5Å; E517-A519 PolarHBondContact O-N 3.29Å; A519-M521 VanDerWaalsContact C-N 3.3Å
520L98.7Very high97.6Very high0 Ų026.7 Ų26.70%013%0.127CC..THydrogen-bonded Turntrans-97.322178.8-57.6174.3000111.4D191 Y192 R194 V195 L203 L237 E517 L518D191-L520 WeakPolarHBondContact CB-O 3.37Å; D191-L520 PolarHBondContact N-O 3.14Å; Y192-L520 HydrophobicContact CD1-CD1 3.68Å; Y192-L520 HydrophobicContact CE1-CD1 4.3Å; R194-L520 WeakPolarHBondContact CD-O 3.22Å; R194-L520 PolarHBondContact NE-O 3.28Å; V195-L520 HydrophobicContact CG2-CD1 4.04Å; V195-L520 HydrophobicContact CG2-CD2 3.71Å; L203-L520 HydrophobicContact CD1-CD2 3.84Å; L237-L520 HydrophobicContact CD2-CD2 3.84Å; E517-L520 WeakPolarHBondContact O-CB 3.41Å; E517-L520 PolarHBondContact O-N 3.42Å; L518-L520 PolarHBondContact O-N 2.84Å
521M98.4Very high97.7Very high0 Ų021 Ų210%010%0.102CC..SBendtrans-128.9165.5175.8-47.8-178.974.600110.4I188 R194 K207 G432 E434 M435 E517 L518 A519 L525I188-M521 HydrophobicContact CG2-SD 3.8Å; R194-M521 VanDerWaalsContact NH1-C 3.28Å; K207-M521 PolarHBondContact NZ-O 2.93Å; G432-M521 CarbonylContact O-C 3.5Å; G432-M521 WeakPolarHBondContact O-CA 3.26Å; G432-M521 WeakPolarHBondContact O-CB 3.38Å; E434-M521 WeakPolarHBondContact O-CE 3.36Å; M435-M521 HydrophobicContact CB-CE 4.47Å; E517-M521 WeakPolarHBondContact O-CG 3.5Å; L518-M521 HydrophobicContact CD2-SD 3.8Å; L518-M521 PolarHBondContact O-N 2.84Å; A519-M521 VanDerWaalsContact C-N 3.3Å; M521-L525 HydrophobicContact CB-CD1 4.41Å; M521-L525 HydrophobicContact CB-CD2 3.73Å; M521-L525 HydrophobicContact CE-CD2 4.06Å; M521-L525 HydrophobicContact SD-CD1 4.29Å
522D97.6Very high97.7Very high46 Ų4618.6 Ų18.625%0.2469%0.092CC..  trans-61.2146.9174-68.62.4000109.9R194 G432 K433 N524 L525R194-D522 IonicContact CZ-OD1 3.73Å; R194-D522 IonicContact NH1-OD1 3.36Å; R194-D522 PolarHBondContact NH1-OD1 2.87Å; R194-D522 VanDerWaalsContact NH1-OD1 3.14Å; R194-D522 IonicContact NH2-OD1 2.84Å; R194-D522 PolarHBondContact NH2-OD1 3.01Å; G432-D522 PolarHBondContact O-N 2.86Å; K433-D522 IonicContact NZ-OD2 3.83Å; K433-D522 PolarHBondContact NZ-OD2 3.22Å; D522-N524 PolarHBondContact O-N 2.82Å; D522-L525 WeakPolarHBondContact O-CD2 3.46Å; D522-L525 VanDerWaalsContact O-CG 3.23Å; D522-L525 WeakPolarHBondContact O-CG 3.36Å
523T95.8Very high97.7Very high17 Ų1718.1 Ų18.110%0.1049%0.091CC..SBendtrans-68.6-36.3-174-72.40000112.8K207 D210 L226 I230K207-T523 PolarHBondContact NZ-OG1 3.08Å; K207-T523 VanDerWaalsContact NZ-OG1 3.14Å; D210-T523 HydrophobicContact CB-CG2 4.2Å; D210-T523 VanDerWaalsContact CG-OG1 3.3Å; D210-T523 WeakPolarHBondContact OD2-CB 3.45Å; D210-T523 PolarHBondContact OD2-OG1 3.42Å; L226-T523 HydrophobicContact CD1-CG2 4.04Å; L226-T523 HydrophobicContact CD2-CG2 4.25Å; L226-T523 HydrophobicContact CG-CG2 4.32Å; I230-T523 HydrophobicContact CD1-CG2 3.52Å; I230-T523 HydrophobicContact CG1-CG2 3.78Å
524N93.2Very high97.7Very high135 Ų13516.7 Ų16.772%0.7229%0.085SC*.SBendtrans-9795.7174.4-65.7-51000109.7D522D522-N524 PolarHBondContact O-N 2.82Å
525L93.8Very high97.7Very high18 Ų1816.6 Ų16.69%0.0949%0.085CC..  trans-91.9136.4-178-62.4173.2000112.4K433 M435 L518 M521 D522 R527K433-L525 WeakPolarHBondContact O-CD2 3.45Å; M435-L525 HydrophobicContact CG-CD1 4.48Å; M435-L525 HydrophobicContact SD-CD1 4.22Å; L518-L525 HydrophobicContact CD2-CD1 3.57Å; M521-L525 HydrophobicContact CB-CD1 4.41Å; M521-L525 HydrophobicContact CB-CD2 3.73Å; M521-L525 HydrophobicContact CE-CD2 4.06Å; M521-L525 HydrophobicContact SD-CD1 4.29Å; D522-L525 WeakPolarHBondContact O-CD2 3.46Å; D522-L525 VanDerWaalsContact O-CG 3.23Å; D522-L525 WeakPolarHBondContact O-CG 3.36Å; L525-R527 PolarHBondContact O-NH1 2.76Å
526K96.1Very high97.7Very high87 Ų8716.4 Ų16.438%0.3788%0.083SC..EExtended strand (participates in β ladder)trans-69.9141.6157.9-168.8-171.4178.7-1720108.4K433 E434 M435 E605K433-K526 PolarHBondContact O-N 3.4Å; E434-K526 WeakPolarHBondContact CA-O 3.38Å; E434-K526 HydrophobicContact CB-CB 4.31Å; E434-K526 HydrophobicContact CG-CB 3.82Å; E434-K526 HydrophobicContact CG-CD 4.29Å; E434-K526 WeakPolarHBondContact OE1-CD 3.46Å; M435-K526 PolarHBondContact N-O 3.25Å; M435-K526 VanDerWaalsContact N-O 3.12Å; K526-E605 WeakPolarHBondContact CE-OE2 3.45Å; K526-E605 IonicContact NZ-OE2 2.76Å; K526-E605 PolarHBondContact NZ-OE2 3.36Å
527R98.1Very high97.7Very high29 Ų2916.4 Ų16.411%0.1098%0.083CC..EExtended strand (participates in β ladder)trans-125.1129.5176.9-67.8173176.775.9-1.6108.6M435 F437 L525 S604 E605M435-R527 HydrophobicContact CG-CG 3.81Å; M435-R527 WeakPolarHBondContact O-CA 3.32Å; M435-R527 HydrophobicContact SD-CG 4.26Å; F437-R527 HydrophobicContact CE2-CB 4.47Å; L525-R527 PolarHBondContact O-NH1 2.76Å; R527-S604 CarbonylContact O-C 3.14Å; R527-S604 WeakPolarHBondContact O-CA 3.08Å; R527-S604 VanDerWaalsContact O-CB 3.29Å; R527-S604 WeakPolarHBondContact O-CB 3.42Å; R527-E605 PolarHBondContact O-N 2.87Å
528T98Very high97.7Very high6 Ų616.6 Ų16.64%0.0378%0.083CC..EExtended strand (participates in β ladder)trans-99.4153.8164.560.70000109.9M435 Q436 F437 E605 T607M435-T528 PolarHBondContact O-N 3.08Å; M435-T528 VanDerWaalsContact O-N 3.1Å; Q436-T528 WeakPolarHBondContact CB-OG1 3.48Å; Q436-T528 WeakPolarHBondContact CG-OG1 3Å; F437-T528 PolarHBondContact N-O 3.4Å; T528-E605 CarbonylContact C-O 3.52Å; T528-E605 WeakPolarHBondContact CA-O 3.46Å; T528-E605 WeakPolarHBondContact CB-O 3.31Å; T528-E605 HydrophobicContact CG2-CB 4.43Å; T528-T607 HydrophobicContact CG2-CG2 3.92Å
529F98.5Very high97.7Very high0 Ų016.6 Ų16.60%08%0.083CC..EExtended strand (participates in β ladder)trans-108.585.5179.3-158.7-93.6000107.8F437 V498 L501 N502 H505 T531 T600 S604 E605 T607F437-F529 HydrophobicContact CB-CD2 4.2Å; F437-F529 HydrophobicContact CD2-CD2 4.1Å; V498-F529 HydrophobicContact CB-CE1 4.34Å; V498-F529 HydrophobicContact CG1-CE1 4.06Å; V498-F529 HydrophobicContact CG1-CZ 4.29Å; V498-F529 HydrophobicContact CG2-CE1 4.27Å; L501-F529 HydrophobicContact CB-CE1 3.5Å; L501-F529 VanDerWaalsContact CB-CE1 3.5Å; L501-F529 HydrophobicContact CB-CE2 4.15Å; L501-F529 HydrophobicContact CB-CZ 3.21Å; L501-F529 HydrophobicContact CD1-CD1 4.24Å; L501-F529 HydrophobicContact CD1-CE1 3.62Å; L501-F529 HydrophobicContact CD1-CZ 4.2Å; L501-F529 HydrophobicContact CG-CE1 4.2Å; L501-F529 HydrophobicContact CG-CZ 4.35Å; N502-F529 WeakPolarHBondContact OD1-CE2 3.06Å; N502-F529 VanDerWaalsContact OD1-CZ 3.32Å; N502-F529 WeakPolarHBondContact OD1-CZ 3.31Å; H505-F529 AromaticContact CD2-CE2 3.74Å; F529-T531 HydrophobicContact CD1-CG2 4.21Å; F529-T531 PolarHBondContact O-N 2.77Å; F529-T531 VanDerWaalsContact O-N 3.12Å; F529-T600 HydrophobicContact CB-CG2 3.89Å; F529-T600 HydrophobicContact CD1-CG2 3.83Å; F529-T600 HydrophobicContact CD2-CG2 4.06Å; F529-T600 HydrophobicContact CE1-CG2 4.25Å; F529-T600 HydrophobicContact CE2-CG2 4.45Å; F529-T600 HydrophobicContact CG-CG2 3.68Å; F529-T600 HydrophobicContact CZ-CG2 4.5Å; F529-S604 WeakPolarHBondContact CB-OG 3.49Å; F529-S604 WeakPolarHBondContact CD2-OG 3.48Å; F529-E605 PolarHBondContact N-O 2.82Å; F529-T607 PolarHBondContact O-N 3.5Å; F529-T607 VanDerWaalsContact O-O 3.06Å
530A98.5Very high97.7Very high1 Ų116.4 Ų16.41%0.0088%0.082CC..EExtended strand (participates in β ladder)trans-76.899.7-167.900000110.9Q436 F437 G439 T607 D668Q436-A530 HydrophobicContact CB-CB 4.07Å; F437-A530 WeakPolarHBondContact O-CB 3.44Å; F437-A530 PolarHBondContact O-N 3.08Å; G439-A530 WeakPolarHBondContact CA-O 3.36Å; G439-A530 PolarHBondContact N-O 2.76Å; A530-T607 WeakPolarHBondContact CA-OG1 3.38Å; A530-D668 HydrophobicContact CB-CB 4.31Å; A530-D668 VanDerWaalsContact CB-CG 3.48Å; A530-D668 VanDerWaalsContact CB-OD1 3.23Å; A530-D668 WeakPolarHBondContact CB-OD1 3.2Å
531T98.7Very high97.7Very high1 Ų116.4 Ų16.41%0.0068%0.082CC..EExtended strand (participates in β ladder)trans-89.3174.5167.764.50000110.7Y497 L501 F529 L595 T607 T608 S609Y497-T531 HydrophobicContact CD1-CG2 4.09Å; Y497-T531 HydrophobicContact CE1-CG2 3.92Å; L501-T531 HydrophobicContact CD1-CG2 4.02Å; F529-T531 HydrophobicContact CD1-CG2 4.21Å; F529-T531 PolarHBondContact O-N 2.77Å; F529-T531 VanDerWaalsContact O-N 3.12Å; T531-L595 HydrophobicContact CG2-CD1 4.32Å; T531-L595 HydrophobicContact CG2-CD2 3.92Å; T531-L595 WeakPolarHBondContact OG1-CD1 3.22Å; T531-T607 PolarHBondContact N-O 2.72Å; T531-T607 PolarHBondContact OG1-O 2.83Å; T531-T608 CarbonylContact O-C 3.57Å; T531-T608 WeakPolarHBondContact O-CA 3.42Å; T531-T608 WeakPolarHBondContact OG1-CB 3.49Å; T531-T608 PolarHBondContact OG1-OG1 3.34Å; T531-S609 PolarHBondContact O-N 3.27Å; T531-S609 PolarHBondContact O-OG 3.15Å
532G98.3Very high97.7Very high0 Ų016.4 Ų16.40%08%0.082CC..EExtended strand (participates in β ladder)trans-154.7157.4-176.700000111.9A440 R441 A442 Y497 S609A440-G532 WeakPolarHBondContact O-CA 3.47Å; R441-G532 CarbonylContact C-O 3.45Å; R441-G532 VanDerWaalsContact CA-O 3.24Å; R441-G532 WeakPolarHBondContact CA-O 3.46Å; R441-G532 WeakPolarHBondContact CB-O 3.48Å; A442-G532 PolarHBondContact N-O 2.84Å; Y497-G532 PolarHBondContact OH-N 3.07Å; G532-S609 CarbonylContact C-O 3.48Å; G532-S609 VanDerWaalsContact CA-O 3.31Å; G532-S609 WeakPolarHBondContact CA-O 3.18Å
533I98.6Very high97.8Very high0 Ų014.2 Ų14.20%07%0.071CC..EExtended strand (participates in β ladder)trans-118132.1-175.1-64.9167.1000109.8L444 F536 L588 F591 T608 S609 I610L444-I533 HydrophobicContact CB-CG2 4.43Å; L444-I533 HydrophobicContact CD1-CB 4.38Å; L444-I533 HydrophobicContact CD1-CG1 4.18Å; L444-I533 HydrophobicContact CD1-CG2 4.02Å; L444-I533 HydrophobicContact CD2-CD1 4.39Å; L444-I533 HydrophobicContact CD2-CG1 4.16Å; L444-I533 HydrophobicContact CD2-CG2 3.71Å; L444-I533 HydrophobicContact CG-CG2 4.25Å; I533-F536 HydrophobicContact CG2-CB 4.04Å; I533-F536 HydrophobicContact CG2-CD2 4.08Å; I533-L588 HydrophobicContact CD1-CD1 4.16Å; I533-F591 HydrophobicContact CD1-CB 4.44Å; I533-F591 HydrophobicContact CD1-CD1 3.82Å; I533-F591 HydrophobicContact CG1-CD1 3.65Å; I533-F591 HydrophobicContact CG1-CE1 3.99Å; I533-T608 HydrophobicContact CD1-CG2 4.46Å; I533-S609 PolarHBondContact N-O 3.32Å; I533-I610 HydrophobicContact CD1-CG1 4.45Å
534A98.4Very high97.9Very high0 Ų013.4 Ų13.40%07%0.066CC..EExtended strand (participates in β ladder)trans-120.3150.1167.300000111.8R441 A442 L444 T612 Y619R441-A534 HydrophobicContact CG-CB 3.77Å; A442-A534 WeakPolarHBondContact O-CB 3.33Å; A442-A534 PolarHBondContact O-N 3.19Å; L444-A534 PolarHBondContact N-O 2.87Å; A534-T612 HydrophobicContact CB-CG2 3.86Å; A534-Y619 HydrophobicContact CB-CD2 3.58Å; A534-Y619 HydrophobicContact CB-CE2 3.9Å
535G97.9Very high98.2Very high0 Ų07 Ų70%03%0.031CC..SBendtrans7721.7-178.800000113.9H538 V539G535-H538 PolarHBondContact O-N 3.14Å; G535-V539 WeakPolarHBondContact O-CG2 3.45Å; G535-V539 PolarHBondContact O-N 3.49Å
536F98.7Very high98.4Very high1 Ų16.6 Ų6.60%0.0043%0.029CC..Hα-helixtrans-54.5-59.2-172.7-178.2-103.9000112.7I533 H538 V539 V540 Y573 A584 V587 L588 I610 L661I533-F536 HydrophobicContact CG2-CB 4.04Å; I533-F536 HydrophobicContact CG2-CD2 4.08Å; F536-H538 VanDerWaalsContact C-N 3.32Å; F536-H538 PolarHBondContact O-N 3.29Å; F536-V539 WeakPolarHBondContact O-CB 3.41Å; F536-V539 PolarHBondContact O-N 2.64Å; F536-V539 VanDerWaalsContact O-N 3.13Å; F536-V540 HydrophobicContact CE1-CG2 4.29Å; F536-V540 HydrophobicContact CZ-CG2 4.39Å; F536-V540 WeakPolarHBondContact O-CG2 3.32Å; F536-V540 PolarHBondContact O-N 2.96Å; F536-Y573 HydrophobicContact CE1-CE1 4.46Å; F536-A584 HydrophobicContact CE1-CB 3.83Å; F536-A584 HydrophobicContact CZ-CB 3.75Å; F536-A584 VanDerWaalsContact CZ-O 3.23Å; F536-A584 WeakPolarHBondContact CZ-O 3.5Å; F536-V587 HydrophobicContact CD2-CG1 3.89Å; F536-V587 HydrophobicContact CE2-CB 3.98Å; F536-V587 HydrophobicContact CE2-CG1 3.81Å; F536-L588 HydrophobicContact CE2-CB 4.16Å; F536-I610 HydrophobicContact CB-CG2 3.68Å; F536-I610 HydrophobicContact CD1-CD1 4.23Å; F536-I610 HydrophobicContact CD1-CG2 4.11Å; F536-I610 HydrophobicContact CD2-CD1 4.01Å; F536-I610 HydrophobicContact CD2-CG1 4.48Å; F536-I610 HydrophobicContact CD2-CG2 4.25Å; F536-I610 HydrophobicContact CE1-CD1 4Å; F536-I610 HydrophobicContact CE2-CD1 3.76Å; F536-I610 HydrophobicContact CG-CD1 4.23Å; F536-I610 HydrophobicContact CG-CG2 3.76Å; F536-I610 HydrophobicContact CZ-CD1 3.75Å; F536-L661 HydrophobicContact CE1-CD1 4.06Å; F536-L661 HydrophobicContact CE1-CD2 3.96Å; F536-L661 HydrophobicContact CZ-CD1 4.4Å; F536-L661 HydrophobicContact CZ-CD2 3.67Å
537S98.5Very high98.5Very high0 Ų06.9 Ų6.90%03%0.03CC..Hα-helixtrans-63.7-35-179.1500000113.2V539 V540 D541 A637 N641 S643S537-V539 VanDerWaalsContact C-N 3.33Å; S537-V539 PolarHBondContact O-N 2.87Å; S537-V540 WeakPolarHBondContact O-CB 3.4Å; S537-V540 PolarHBondContact O-N 3.16Å; S537-D541 WeakPolarHBondContact O-CB 3.37Å; S537-D541 VanDerWaalsContact O-CG 3.31Å; S537-D541 PolarHBondContact O-N 3.42Å; S537-A637 VanDerWaalsContact OG-CB 3.22Å; S537-A637 WeakPolarHBondContact OG-CB 3.49Å; S537-N641 WeakPolarHBondContact CB-O 3.5Å; S537-N641 PolarHBondContact OG-O 2.96Å; S537-S643 PolarHBondContact OG-N 2.92Å
538H98.6Very high98.6Very high4 Ų49.5 Ų9.52%0.0194%0.041CC..Hα-helixtrans-65.4-34.4175-70-64.6000113G535 F536 S542 D628 R630 L636 A637 S643G535-H538 PolarHBondContact O-N 3.14Å; F536-H538 VanDerWaalsContact C-N 3.32Å; F536-H538 PolarHBondContact O-N 3.29Å; H538-S542 WeakPolarHBondContact O-CB 3.4Å; H538-S542 PolarHBondContact O-N 3.5Å; H538-S542 PolarHBondContact O-OG 2.86Å; H538-D628 IonicContact CE1-OD2 2.83Å; H538-D628 IonicContact CG-OD2 2.79Å; H538-D628 IonicContact ND1-OD2 3.63Å; H538-D628 PolarHBondContact ND1-OD2 2.83Å; H538-R630 VanDerWaalsContact CE1-CD 3.41Å; H538-R630 WeakPolarHBondContact CE1-CD 3.37Å; H538-L636 HydrophobicContact CB-CD2 4.36Å; H538-L636 WeakPolarHBondContact NE2-CA 3.35Å; H538-A637 PolarHBondContact CD2-N 2.96Å; H538-A637 PolarHBondContact NE2-N 2.84Å; H538-A637 VanDerWaalsContact NE2-N 3.19Å; H538-S643 VanDerWaalsContact CE1-CB 3.49Å; H538-S643 WeakPolarHBondContact CE1-CB 3.42Å
539V98.8Very high98.6Very high0 Ų09.9 Ų9.90%05%0.045CC..Hα-helixtrans-66.3-47.3171.3171.40000109.9L444 A445 Y486 G535 F536 S537 D541 S542 L543 V587L444-V539 HydrophobicContact CB-CG2 4.09Å; A445-V539 HydrophobicContact CB-CG2 4.35Å; Y486-V539 HydrophobicContact CE1-CG1 3.66Å; Y486-V539 WeakPolarHBondContact OH-CG1 3.44Å; G535-V539 WeakPolarHBondContact O-CG2 3.45Å; G535-V539 PolarHBondContact O-N 3.49Å; F536-V539 WeakPolarHBondContact O-CB 3.41Å; F536-V539 PolarHBondContact O-N 2.64Å; F536-V539 VanDerWaalsContact O-N 3.13Å; S537-V539 VanDerWaalsContact C-N 3.33Å; S537-V539 PolarHBondContact O-N 2.87Å; V539-D541 PolarHBondContact O-N 3.33Å; V539-S542 PolarHBondContact O-N 3.16Å; V539-L543 HydrophobicContact CG1-CD1 3.95Å; V539-L543 HydrophobicContact CG1-CG 4.35Å; V539-L543 WeakPolarHBondContact O-CB 3.43Å; V539-L543 VanDerWaalsContact O-CG 3.29Å; V539-L543 WeakPolarHBondContact O-CG 3.26Å; V539-L543 PolarHBondContact O-N 3.47Å; V539-V587 HydrophobicContact CG1-CG1 4.35Å; V539-V587 HydrophobicContact CG1-CG2 3.78Å
540V98.8Very high98.6Very high0 Ų015.6 Ų15.60%07%0.069CC..Hα-helixtrans-57.2-51.8179.3175.60000111.2F536 S537 S542 L543 A544 Y573 A580 L583 A584 V587F536-V540 HydrophobicContact CE1-CG2 4.29Å; F536-V540 HydrophobicContact CZ-CG2 4.39Å; F536-V540 WeakPolarHBondContact O-CG2 3.32Å; F536-V540 PolarHBondContact O-N 2.96Å; S537-V540 WeakPolarHBondContact O-CB 3.4Å; S537-V540 PolarHBondContact O-N 3.16Å; V540-S542 VanDerWaalsContact C-N 3.3Å; V540-S542 PolarHBondContact O-N 3.14Å; V540-L543 PolarHBondContact O-N 2.83Å; V540-A544 WeakPolarHBondContact O-CB 3.5Å; V540-A544 PolarHBondContact O-N 3.39Å; V540-Y573 HydrophobicContact CG1-CG 4.38Å; V540-A580 HydrophobicContact CG1-CB 4.36Å; V540-A580 WeakPolarHBondContact CG1-O 3.24Å; V540-L583 HydrophobicContact CG1-CB 4.1Å; V540-A584 HydrophobicContact CG1-CB 4.11Å; V540-A584 VanDerWaalsContact CG2-CA 3.43Å; V540-A584 HydrophobicContact CG2-CB 3.71Å; V540-V587 HydrophobicContact CG2-CG2 4.29Å
541D98.8Very high98.6Very high0 Ų015.5 Ų15.50%07%0.069CC..Hα-helixtrans-67-33.3-179.3-69.4-13.7000111.6S537 V539 A544 A545 F570 K572 Y573 D628 S643S537-D541 WeakPolarHBondContact O-CB 3.37Å; S537-D541 VanDerWaalsContact O-CG 3.31Å; S537-D541 PolarHBondContact O-N 3.42Å; V539-D541 PolarHBondContact O-N 3.33Å; D541-A544 PolarHBondContact O-N 3Å; D541-A545 WeakPolarHBondContact O-CB 3.31Å; D541-A545 PolarHBondContact O-N 2.98Å; D541-F570 HydrophobicContact CB-CE2 4.33Å; D541-F570 WeakPolarHBondContact O-CE2 3.49Å; D541-K572 VanDerWaalsContact OD1-CA 3.32Å; D541-K572 WeakPolarHBondContact OD1-CA 3.37Å; D541-Y573 WeakPolarHBondContact OD1-CB 3.19Å; D541-Y573 PolarHBondContact OD1-N 3.47Å; D541-D628 HydrophobicContact CB-CB 3.69Å; D541-S643 WeakPolarHBondContact OD2-CB 3.18Å; D541-S643 PolarHBondContact OD2-OG 2.9Å
542S98.8Very high98.6Very high0 Ų018.2 Ų18.20%08%0.081CC..Hα-helixtrans-67-44.5175.6-70.50000111.3H538 V539 V540 A544 A545 I546 P627 D628H538-S542 WeakPolarHBondContact O-CB 3.4Å; H538-S542 PolarHBondContact O-N 3.5Å; H538-S542 PolarHBondContact O-OG 2.86Å; V539-S542 PolarHBondContact O-N 3.16Å; V540-S542 VanDerWaalsContact C-N 3.3Å; V540-S542 PolarHBondContact O-N 3.14Å; S542-A544 VanDerWaalsContact C-N 3.32Å; S542-A545 PolarHBondContact O-N 3.35Å; S542-I546 WeakPolarHBondContact O-CD1 3.47Å; S542-I546 VanDerWaalsContact O-CG1 3.23Å; S542-I546 WeakPolarHBondContact O-CG1 3.41Å; S542-I546 PolarHBondContact O-N 2.95Å; S542-P627 WeakPolarHBondContact OG-CD 3.44Å; S542-D628 PolarHBondContact OG-N 3.41Å
543L98.9Very high98.6Very high0 Ų018.8 Ų18.80%08%0.084CC..Hα-helixtrans-64.7-38.7174.9-68.6177000111.1L448 F479 V482 M483 V539 V540 I546 K547 L583 W586 V587L448-L543 HydrophobicContact CD1-CD2 4.22Å; F479-L543 HydrophobicContact CE2-CB 4.28Å; V482-L543 HydrophobicContact CG1-CD2 4.23Å; M483-L543 HydrophobicContact SD-CD1 3.89Å; M483-L543 HydrophobicContact SD-CD2 3.68Å; M483-L543 HydrophobicContact SD-CG 4.35Å; V539-L543 HydrophobicContact CG1-CD1 3.95Å; V539-L543 HydrophobicContact CG1-CG 4.35Å; V539-L543 WeakPolarHBondContact O-CB 3.43Å; V539-L543 VanDerWaalsContact O-CG 3.29Å; V539-L543 WeakPolarHBondContact O-CG 3.26Å; V539-L543 PolarHBondContact O-N 3.47Å; V540-L543 PolarHBondContact O-N 2.83Å; L543-I546 PolarHBondContact O-N 3.43Å; L543-K547 VanDerWaalsContact O-CB 3.31Å; L543-K547 WeakPolarHBondContact O-CB 3.23Å; L543-K547 PolarHBondContact O-N 3.45Å; L543-L583 HydrophobicContact CB-CD1 4.07Å; L543-W586 HydrophobicContact CD1-CE3 4.39Å; L543-W586 HydrophobicContact CD1-CZ3 4.19Å; L543-V587 HydrophobicContact CD1-CG2 4.05Å
544A98.7Very high98.6Very high0 Ų022.4 Ų22.40%010%0.103CC..Hα-helixtrans-65.2-42.6174.900000112.1V540 D541 S542 I546 K547 Y548 F570 P571 L583V540-A544 WeakPolarHBondContact O-CB 3.5Å; V540-A544 PolarHBondContact O-N 3.39Å; D541-A544 PolarHBondContact O-N 3Å; S542-A544 VanDerWaalsContact C-N 3.32Å; A544-I546 PolarHBondContact O-N 3.36Å; A544-K547 PolarHBondContact O-N 2.85Å; A544-Y548 HydrophobicContact CB-CD2 4.32Å; A544-Y548 WeakPolarHBondContact O-CB 3.14Å; A544-Y548 VanDerWaalsContact O-CD2 3.3Å; A544-Y548 WeakPolarHBondContact O-CD2 3.28Å; A544-Y548 PolarHBondContact O-N 3.46Å; A544-F570 HydrophobicContact CB-CD2 4.26Å; A544-P571 HydrophobicContact CB-CG 4.36Å; A544-P571 VanDerWaalsContact CB-O 3.29Å; A544-P571 WeakPolarHBondContact CB-O 3.34Å; A544-L583 HydrophobicContact CB-CD1 3.9Å
545A98.8Very high98.5Very high0 Ų025.4 Ų25.40%011%0.114CC..Hα-helixtrans-59.4-46.4175.400000111.5D541 S542 K547 A549 V551 F570 P627D541-A545 WeakPolarHBondContact O-CB 3.31Å; D541-A545 PolarHBondContact O-N 2.98Å; S542-A545 PolarHBondContact O-N 3.35Å; A545-K547 VanDerWaalsContact C-N 3.31Å; A545-K547 PolarHBondContact O-N 3.16Å; A545-A549 CarbonylContact O-C 3.42Å; A545-A549 WeakPolarHBondContact O-CA 3.44Å; A545-A549 WeakPolarHBondContact O-CB 3.45Å; A545-A549 PolarHBondContact O-N 3.29Å; A545-V551 HydrophobicContact CB-CG2 3.86Å; A545-F570 HydrophobicContact CB-CD1 3.85Å; A545-F570 HydrophobicContact CB-CD2 3.78Å; A545-F570 HydrophobicContact CB-CE1 3.85Å; A545-F570 HydrophobicContact CB-CE2 3.78Å; A545-F570 HydrophobicContact CB-CG 3.82Å; A545-F570 HydrophobicContact CB-CZ 3.82Å; A545-P627 WeakPolarHBondContact CB-O 3.34Å
546I98.7Very high98.4Very high9 Ų927.3 Ų27.35%0.04613%0.125CC..Hα-helixtrans-64-37.5178.2-65.8164.4000111.2L477 F479 V482 S542 L543 A544 V551 P627L477-I546 HydrophobicContact CB-CG1 4.32Å; L477-I546 HydrophobicContact CB-CG2 3.99Å; L477-I546 HydrophobicContact CD1-CD1 3.9Å; L477-I546 HydrophobicContact CD1-CG1 4.07Å; F479-I546 HydrophobicContact CB-CG2 4.12Å; F479-I546 HydrophobicContact CD2-CG2 4.4Å; V482-I546 HydrophobicContact CG1-CD1 4.01Å; V482-I546 HydrophobicContact CG2-CD1 4.26Å; V482-I546 HydrophobicContact CG2-CG2 4.42Å; S542-I546 WeakPolarHBondContact O-CD1 3.47Å; S542-I546 VanDerWaalsContact O-CG1 3.23Å; S542-I546 WeakPolarHBondContact O-CG1 3.41Å; S542-I546 PolarHBondContact O-N 2.95Å; L543-I546 PolarHBondContact O-N 3.43Å; A544-I546 PolarHBondContact O-N 3.36Å; I546-V551 HydrophobicContact CG1-CB 4.14Å; I546-V551 HydrophobicContact CG1-CG2 3.96Å; I546-P627 HydrophobicContact CD1-CB 3.88Å; I546-P627 HydrophobicContact CD1-CG 4.06Å; I546-P627 HydrophobicContact CG1-CB 4.04Å
547K98.6Very high98.2Very high93 Ų9336.1 Ų36.140%0.40417%0.166SC..Hα-helixtrans-77.6-38.8-176.9-167.2171.1-175.9177.70114.2F479 L543 A544 A545F479-K547 HydrophobicContact CB-CB 4.48Å; F479-K547 HydrophobicContact CD1-CD 4.22Å; F479-K547 HydrophobicContact CD1-CG 4.29Å; F479-K547 HydrophobicContact CD2-CB 3.55Å; F479-K547 HydrophobicContact CD2-CD 4.11Å; F479-K547 HydrophobicContact CD2-CG 3.98Å; F479-K547 HydrophobicContact CE1-CD 3.96Å; F479-K547 HydrophobicContact CE2-CB 3.92Å; F479-K547 HydrophobicContact CE2-CD 3.84Å; F479-K547 HydrophobicContact CE2-CG 4.23Å; F479-K547 HydrophobicContact CG-CB 4Å; F479-K547 HydrophobicContact CG-CD 4.29Å; F479-K547 HydrophobicContact CG-CG 4.01Å; F479-K547 HydrophobicContact CZ-CD 3.77Å; L543-K547 VanDerWaalsContact O-CB 3.31Å; L543-K547 WeakPolarHBondContact O-CB 3.23Å; L543-K547 PolarHBondContact O-N 3.45Å; A544-K547 PolarHBondContact O-N 2.85Å; A545-K547 VanDerWaalsContact C-N 3.31Å; A545-K547 PolarHBondContact O-N 3.16Å
548Y98.6Very high98Very high84 Ų8441.1 Ų41.133%0.32919%0.192SC..Hα-helixtrans-113.5-15.9-167.3-61.7-68.7000114.1A544 P571 R579A544-Y548 HydrophobicContact CB-CD2 4.32Å; A544-Y548 WeakPolarHBondContact O-CB 3.14Å; A544-Y548 VanDerWaalsContact O-CD2 3.3Å; A544-Y548 WeakPolarHBondContact O-CD2 3.28Å; A544-Y548 PolarHBondContact O-N 3.46Å; Y548-P571 HydrophobicContact CD2-CG 3.6Å; Y548-P571 HydrophobicContact CE2-CG 3.99Å; Y548-P571 HydrophobicContact CG-CG 4.21Å; Y548-R579 HydrophobicContact CE1-CG 4.42Å; Y548-R579 HydrophobicContact CE2-CB 3.79Å
549A98.5Very high97.8Very high15 Ų1542.5 Ų42.512%0.12421%0.208CC..SBendtrans-116.5-166.5169.400000109.9A545 I566 F570A545-A549 CarbonylContact O-C 3.42Å; A545-A549 WeakPolarHBondContact O-CA 3.44Å; A545-A549 WeakPolarHBondContact O-CB 3.45Å; A545-A549 PolarHBondContact O-N 3.29Å; A549-I566 HydrophobicContact CB-CG2 4.03Å; A549-F570 HydrophobicContact CB-CB 4.22Å; A549-F570 HydrophobicContact CB-CD1 4.29Å
550K98.5Very high97.7Very high119 Ų11943.5 Ų43.552%0.51721%0.213SC..EExtended strand (participates in β ladder)trans-116.3112.1171.2-65.2179-178.1177.10109.5A476 F552 I566 D567A476-K550 HydrophobicContact CB-CB 4.04Å; A476-K550 HydrophobicContact CB-CG 4.46Å; K550-F552 HydrophobicContact CB-CD2 4.49Å; K550-F552 HydrophobicContact CB-CE2 3.69Å; K550-F552 HydrophobicContact CB-CZ 4.12Å; K550-F552 HydrophobicContact CD-CZ 4.34Å; K550-I566 CarbonylContact O-C 3.58Å; K550-I566 WeakPolarHBondContact O-CA 3.35Å; K550-D567 HydrophobicContact CB-CB 4.26Å; K550-D567 PolarHBondContact N-O 3.33Å; K550-D567 PolarHBondContact O-N 3.04Å
551V98.7Very high97.7Very high0 Ų043.7 Ų43.70%021%0.214CC..EExtended strand (participates in β ladder)trans-104114.8179-174.80000109.5A476 L477 A545 I546 F564 K565 I566 P627A476-V551 CarbonylContact C-O 3.59Å; A476-V551 VanDerWaalsContact CA-O 3.27Å; A476-V551 WeakPolarHBondContact CA-O 3.46Å; L477-V551 HydrophobicContact CD1-CB 4.45Å; L477-V551 HydrophobicContact CD1-CG1 4.16Å; L477-V551 PolarHBondContact N-O 2.89Å; A545-V551 HydrophobicContact CB-CG2 3.86Å; I546-V551 HydrophobicContact CG1-CB 4.14Å; I546-V551 HydrophobicContact CG1-CG2 3.96Å; V551-F564 HydrophobicContact CG1-CB 3.86Å; V551-F564 HydrophobicContact CG1-CD1 3.72Å; V551-F564 HydrophobicContact CG1-CG 4.07Å; V551-K565 CarbonylContact C-O 3.48Å; V551-K565 WeakPolarHBondContact CA-O 3.32Å; V551-I566 HydrophobicContact CG2-CG1 4.35Å; V551-I566 HydrophobicContact CG2-CG2 4.47Å; V551-P627 HydrophobicContact CG1-CB 4.1Å
552F98.4Very high97.6Very high58 Ų5846.1 Ų46.125%0.25423%0.229SC..EExtended strand (participates in β ladder)trans-99.1125.5178.6-60.8-92.7000110.2A476 K550 F564 K565 D567A476-F552 HydrophobicContact CB-CD1 4.23Å; A476-F552 HydrophobicContact CB-CE1 3.94Å; A476-F552 HydrophobicContact CB-CE2 4.49Å; A476-F552 HydrophobicContact CB-CZ 4.08Å; K550-F552 HydrophobicContact CB-CD2 4.49Å; K550-F552 HydrophobicContact CB-CE2 3.69Å; K550-F552 HydrophobicContact CB-CZ 4.12Å; K550-F552 HydrophobicContact CD-CZ 4.34Å; F552-F564 WeakPolarHBondContact O-CA 3.43Å; F552-K565 HydrophobicContact CB-CB 4.37Å; F552-K565 PolarHBondContact N-O 3.34Å; F552-K565 PolarHBondContact O-N 2.87Å; F552-D567 HydrophobicContact CE2-CB 4.17Å
553P98.2Very high97.6Very high11 Ų1148.5 Ų48.57%0.07124%0.241CC..EExtended strand (participates in β ladder)trans-69.4139.4175.929.3-32.4000110.9D475 L477 V561 F564D475-P553 VanDerWaalsContact O-CD 3.28Å; D475-P553 WeakPolarHBondContact O-CD 3.08Å; L477-P553 HydrophobicContact CD2-CB 4.33Å; L477-P553 HydrophobicContact CD2-CG 4.06Å; P553-V561 HydrophobicContact CB-CB 4.35Å; P553-V561 HydrophobicContact CB-CG1 3.61Å; P553-V561 HydrophobicContact CB-CG2 3.72Å; P553-F564 HydrophobicContact CB-CE1 4.37Å
554I97.8Very high97.6Very high77 Ų7749.1 Ų49.140%0.39524%0.244SC..EExtended strand (participates in β ladder)trans-112.8116.8172.1-57174.8000107.7V561 T562 D563 K565I554-V561 WeakPolarHBondContact O-CA 3.5Å; I554-T562 PolarHBondContact O-N 2.97Å; I554-D563 HydrophobicContact CB-CB 4.04Å; I554-D563 WeakPolarHBondContact CB-O 3.47Å; I554-D563 HydrophobicContact CD1-CB 4.19Å; I554-D563 HydrophobicContact CG2-CB 4.48Å; I554-D563 PolarHBondContact N-O 3.26Å; I554-D563 PolarHBondContact O-N 3.49Å; I554-K565 HydrophobicContact CD1-CB 4.31Å
555R97.2Very high97.5Very high63 Ų6355.3 Ų55.324%0.23827%0.271CS..EExtended strand (participates in β ladder)trans-95.9149.1-177.3-61.7173.2-167.2-78.3-5.7112I471 S473 D474 G559 I560 V561I471-R555 PolarHBondContact O-NH1 2.93Å; I471-R555 PolarHBondContact O-NH2 3.44Å; S473-R555 PolarHBondContact O-NH2 3.06Å; D474-R555 IonicContact OD1-NE 3.48Å; D474-R555 PolarHBondContact OD1-NE 2.72Å; R555-G559 WeakPolarHBondContact CD-O 3.35Å; R555-G559 PolarHBondContact NH1-O 2.9Å; R555-I560 CarbonylContact C-O 3.56Å; R555-I560 WeakPolarHBondContact CA-O 3.47Å; R555-V561 HydrophobicContact CG-CG2 3.95Å
556D96Very high97.5Very high40 Ų4057.7 Ų57.721%0.21428%0.284CS..  trans-83.2-174.5166.677.9-5000111.9K461 D558 G559 I560 T562K461-D556 WeakPolarHBondContact CE-OD2 3.48Å; K461-D556 IonicContact NZ-OD2 3.85Å; K461-D556 PolarHBondContact NZ-OD2 2.82Å; D556-D558 PolarHBondContact O-N 3.16Å; D556-D558 WeakPolarHBondContact OD1-CA 2.9Å; D556-D558 PolarHBondContact OD1-N 3.47Å; D556-G559 PolarHBondContact O-N 2.89Å; D556-G559 VanDerWaalsContact O-N 3.09Å; D556-G559 PolarHBondContact OD1-N 2.94Å; D556-I560 PolarHBondContact N-O 3.19Å; D556-I560 PolarHBondContact OD1-N 3.14Å; D556-T562 HydrophobicContact CB-CG2 4.12Å
557E95.2Very high97.5Very high186 Ų18661.6 Ų61.687%0.86930%0.304SS*.THydrogen-bonded Turntrans-64.9-18.4179.461-158.4-162.600114.9G559E557-G559 VanDerWaalsContact C-N 3.35Å
558D93.2Very high97.4Very high104 Ų10459.2 Ų59.256%0.55631%0.307SS*.THydrogen-bonded Turntrans-92.41.8175.5-65.3-49.7000112.1K461 D556 I560K461-D558 VanDerWaalsContact CD-OD2 3.29Å; K461-D558 WeakPolarHBondContact CD-OD2 3.24Å; K461-D558 IonicContact NZ-OD2 3.46Å; K461-D558 PolarHBondContact NZ-OD2 3.45Å; D556-D558 PolarHBondContact O-N 3.16Å; D556-D558 WeakPolarHBondContact OD1-CA 2.9Å; D556-D558 PolarHBondContact OD1-N 3.47Å; D558-I560 VanDerWaalsContact C-N 3.28Å; D558-I560 HydrophobicContact CB-CG1 4.19Å
559G94.4Very high97.3Very high33 Ų3363.8 Ų63.834%0.3433%0.331SS..SBendtrans80.46.5-178.500000114.3R555 D556 E557R555-G559 WeakPolarHBondContact CD-O 3.35Å; R555-G559 PolarHBondContact NH1-O 2.9Å; D556-G559 PolarHBondContact O-N 2.89Å; D556-G559 VanDerWaalsContact O-N 3.09Å; D556-G559 PolarHBondContact OD1-N 2.94Å; E557-G559 VanDerWaalsContact C-N 3.35Å
560I97.2Very high97.3Very high22 Ų2264.6 Ų64.611%0.11333%0.332CS..  trans-82.3132.3-179.7-57-57.1000109.2V456 E458 R555 D556 D558 T562V456-I560 HydrophobicContact CB-CD1 4.09Å; V456-I560 HydrophobicContact CG1-CD1 3.75Å; V456-I560 HydrophobicContact CG1-CG1 4.44Å; V456-I560 HydrophobicContact CG2-CD1 4.38Å; E458-I560 HydrophobicContact CB-CG2 4.45Å; R555-I560 CarbonylContact C-O 3.56Å; R555-I560 WeakPolarHBondContact CA-O 3.47Å; D556-I560 PolarHBondContact N-O 3.19Å; D556-I560 PolarHBondContact OD1-N 3.14Å; D558-I560 VanDerWaalsContact C-N 3.28Å; D558-I560 HydrophobicContact CB-CG1 4.19Å; I560-T562 HydrophobicContact CG2-CG2 4.33Å; I560-T562 PolarHBondContact O-N 3.44Å
561V98Very high97.3Very high3 Ų359.2 Ų59.22%0.01831%0.309CS..EExtended strand (participates in β ladder)trans-72.4116.7174.9-174.40000109I452 N453 P553 I554 R555 F564I452-V561 HydrophobicContact CG2-CB 4.01Å; I452-V561 HydrophobicContact CG2-CG1 4.34Å; I452-V561 HydrophobicContact CG2-CG2 3.78Å; N453-V561 PolarHBondContact ND2-O 3.18Å; N453-V561 VanDerWaalsContact OD1-CB 3.26Å; N453-V561 WeakPolarHBondContact OD1-CB 3.09Å; N453-V561 WeakPolarHBondContact OD1-CG2 3.17Å; N453-V561 PolarHBondContact OD1-N 3.04Å; P553-V561 HydrophobicContact CB-CB 4.35Å; P553-V561 HydrophobicContact CB-CG1 3.61Å; P553-V561 HydrophobicContact CB-CG2 3.72Å; I554-V561 WeakPolarHBondContact O-CA 3.5Å; R555-V561 HydrophobicContact CG-CG2 3.95Å; V561-F564 HydrophobicContact CG1-CD1 4.2Å; V561-F564 HydrophobicContact CG1-CE1 3.48Å; V561-F564 VanDerWaalsContact CG1-CE1 3.48Å; V561-F564 HydrophobicContact CG1-CE2 4.29Å; V561-F564 HydrophobicContact CG1-CZ 3.54Å
562T97.4Very high97.3Very high51 Ų5162.1 Ų62.131%0.31332%0.321SS..EExtended strand (participates in β ladder)trans-118.2-15.7-17755.60000113.7I554 D556 I560I554-T562 PolarHBondContact O-N 2.97Å; D556-T562 HydrophobicContact CB-CG2 4.12Å; I560-T562 HydrophobicContact CG2-CG2 4.33Å; I560-T562 PolarHBondContact O-N 3.44Å
563D98.1Very high97.3Very high50 Ų5059.3 Ų59.327%0.26731%0.309SS..EExtended strand (participates in β ladder)trans-148.6171.3176.6-154.4-16.7000110.5I554 T625 K631I554-D563 HydrophobicContact CB-CB 4.04Å; I554-D563 WeakPolarHBondContact CB-O 3.47Å; I554-D563 HydrophobicContact CD1-CB 4.19Å; I554-D563 HydrophobicContact CG2-CB 4.48Å; I554-D563 PolarHBondContact N-O 3.26Å; I554-D563 PolarHBondContact O-N 3.49Å; D563-T625 WeakPolarHBondContact OD1-CG2 3.3Å; D563-K631 IonicContact OD1-NZ 3.19Å; D563-K631 PolarHBondContact OD1-NZ 3.35Å; D563-K631 IonicContact OD2-NZ 3.82Å
564F98.3Very high97.3Very high13 Ų1358.8 Ų58.86%0.05731%0.306CS..EExtended strand (participates in β ladder)trans-138.3141.3-178.5-61.3-81.7000110.9L449 I452 L477 V551 F552 P553 V561 T625 P627L449-F564 HydrophobicContact CD2-CE2 4.01Å; L449-F564 HydrophobicContact CD2-CZ 4.19Å; I452-F564 HydrophobicContact CD1-CE1 4.06Å; I452-F564 HydrophobicContact CD1-CZ 3.79Å; L477-F564 HydrophobicContact CD1-CD1 4.27Å; L477-F564 HydrophobicContact CD1-CE1 3.9Å; V551-F564 HydrophobicContact CG1-CB 3.86Å; V551-F564 HydrophobicContact CG1-CD1 3.72Å; V551-F564 HydrophobicContact CG1-CG 4.07Å; F552-F564 WeakPolarHBondContact O-CA 3.43Å; P553-F564 HydrophobicContact CB-CE1 4.37Å; V561-F564 HydrophobicContact CG1-CD1 4.2Å; V561-F564 HydrophobicContact CG1-CE1 3.48Å; V561-F564 VanDerWaalsContact CG1-CE1 3.48Å; V561-F564 HydrophobicContact CG1-CE2 4.29Å; V561-F564 HydrophobicContact CG1-CZ 3.54Å; F564-T625 HydrophobicContact CD2-CG2 4.25Å; F564-T625 VanDerWaalsContact CE2-O 3.24Å; F564-T625 WeakPolarHBondContact CE2-O 3.4Å; F564-P627 HydrophobicContact CD1-CG 4.5Å; F564-P627 HydrophobicContact CD2-CG 4.37Å; F564-P627 HydrophobicContact CE1-CG 4.19Å; F564-P627 HydrophobicContact CE2-CG 4.06Å; F564-P627 HydrophobicContact CZ-CG 3.96Å
565K98.2Very high97.3Very high130 Ų13056.1 Ų56.157%0.56529%0.293SS*.EExtended strand (participates in β ladder)trans-106.1124.7166.9179.4-171.7172.3-1680109.3V551 F552 I554V551-K565 CarbonylContact C-O 3.48Å; V551-K565 WeakPolarHBondContact CA-O 3.32Å; F552-K565 HydrophobicContact CB-CB 4.37Å; F552-K565 PolarHBondContact N-O 3.34Å; F552-K565 PolarHBondContact O-N 2.87Å; I554-K565 HydrophobicContact CD1-CB 4.31Å
566I98.3Very high97.3Very high51 Ų5156.8 Ų56.826%0.26230%0.301SS..EExtended strand (participates in β ladder)trans-103.1129.1178.2-49.8171.3000108.9A549 K550 V551 F570 P627A549-I566 HydrophobicContact CB-CG2 4.03Å; K550-I566 CarbonylContact O-C 3.58Å; K550-I566 WeakPolarHBondContact O-CA 3.35Å; V551-I566 HydrophobicContact CG2-CG1 4.35Å; V551-I566 HydrophobicContact CG2-CG2 4.47Å; I566-F570 HydrophobicContact CD1-CE1 4.25Å; I566-F570 HydrophobicContact CG2-CD1 4.33Å; I566-F570 HydrophobicContact CG2-CE1 4.22Å; I566-P627 WeakPolarHBondContact CD1-O 3.23Å
567D98.2Very high97.4Very high90 Ų9056.9 Ų56.948%0.48130%0.301SS..EExtended strand (participates in β ladder)trans-120.5110.1172.7-179.529.8000109.6K550 F552K550-D567 HydrophobicContact CB-CB 4.26Å; K550-D567 PolarHBondContact N-O 3.33Å; K550-D567 PolarHBondContact O-N 3.04Å; F552-D567 HydrophobicContact CE2-CB 4.17Å
568G97.3Very high97.5Very high44 Ų4450.8 Ų50.845%0.45428%0.282SS..SBendtrans111.6161.8-175.600000114
569E96.9Very high97.8Very high179 Ų17951.3 Ų51.384%0.83628%0.277SS*.  trans-87.6151.6173-65.7-66.3145.300110.4
570F98.1Very high98Very high32 Ų3249.7 Ų49.714%0.1426%0.26CS..  trans-142.6152.7178.461.9-85.4000110.8D541 A544 A545 A549 I566 K572 D628D541-F570 HydrophobicContact CB-CE2 4.33Å; D541-F570 WeakPolarHBondContact O-CE2 3.49Å; A544-F570 HydrophobicContact CB-CD2 4.26Å; A545-F570 HydrophobicContact CB-CD1 3.85Å; A545-F570 HydrophobicContact CB-CD2 3.78Å; A545-F570 HydrophobicContact CB-CE1 3.85Å; A545-F570 HydrophobicContact CB-CE2 3.78Å; A545-F570 HydrophobicContact CB-CG 3.82Å; A545-F570 HydrophobicContact CB-CZ 3.82Å; A549-F570 HydrophobicContact CB-CB 4.22Å; A549-F570 HydrophobicContact CB-CD1 4.29Å; I566-F570 HydrophobicContact CD1-CE1 4.25Å; I566-F570 HydrophobicContact CG2-CD1 4.33Å; I566-F570 HydrophobicContact CG2-CE1 4.22Å; F570-K572 HydrophobicContact CD2-CG 4.26Å; F570-K572 HydrophobicContact CE2-CD 4.5Å; F570-K572 HydrophobicContact CE2-CG 3.84Å; F570-D628 HydrophobicContact CZ-CB 4.48Å
571P97.9Very high98.1Very high7 Ų748.8 Ų48.85%0.04526%0.256CS..  trans-68141.2176.128.7-32.8000110.5A544 Y548 D577 R579 A580A544-P571 HydrophobicContact CB-CG 4.36Å; A544-P571 VanDerWaalsContact CB-O 3.29Å; A544-P571 WeakPolarHBondContact CB-O 3.34Å; Y548-P571 HydrophobicContact CD2-CG 3.6Å; Y548-P571 HydrophobicContact CE2-CG 3.99Å; Y548-P571 HydrophobicContact CG-CG 4.21Å; P571-D577 HydrophobicContact CB-CB 4.37Å; P571-R579 HydrophobicContact CB-CB 4.21Å; P571-R579 HydrophobicContact CG-CB 3.68Å; P571-A580 HydrophobicContact CB-CB 4.24Å
572K98.2Very high98.1Very high60 Ų6053.9 Ų53.926%0.26128%0.283SS..  trans-114.5142174-64-172.8175.8-168.70110.7D541 F570 N575 A646D541-K572 VanDerWaalsContact OD1-CA 3.32Å; D541-K572 WeakPolarHBondContact OD1-CA 3.37Å; F570-K572 HydrophobicContact CD2-CG 4.26Å; F570-K572 HydrophobicContact CE2-CD 4.5Å; F570-K572 HydrophobicContact CE2-CG 3.84Å; K572-N575 PolarHBondContact O-ND2 2.55Å; K572-A646 HydrophobicContact CB-CB 3.87Å; K572-A646 HydrophobicContact CD-CB 3.89Å
573Y98.4Very high98.2Very high0 Ų052 Ų520%027%0.271CS..SBendtrans-56.1140.7173.9178.2-115.8000111.2F536 V540 D541 D581 A584 A640 P642 L658 L661F536-Y573 HydrophobicContact CE1-CE1 4.46Å; V540-Y573 HydrophobicContact CG1-CG 4.38Å; D541-Y573 WeakPolarHBondContact OD1-CB 3.19Å; D541-Y573 PolarHBondContact OD1-N 3.47Å; Y573-D581 WeakPolarHBondContact CD2-OD1 3.41Å; Y573-A584 HydrophobicContact CD2-CB 3.92Å; Y573-A584 HydrophobicContact CE2-CB 3.85Å; Y573-A640 WeakPolarHBondContact CE1-O 3.43Å; Y573-P642 HydrophobicContact CD1-CB 4.49Å; Y573-P642 HydrophobicContact CD1-CG 4.34Å; Y573-P642 HydrophobicContact CE1-CG 4.41Å; Y573-P642 WeakPolarHBondContact O-CB 3.48Å; Y573-L658 HydrophobicContact CE1-CD1 4.05Å; Y573-L658 VanDerWaalsContact OH-CD1 3.31Å; Y573-L658 WeakPolarHBondContact OH-CD1 3.31Å; Y573-L658 WeakPolarHBondContact OH-CG 3.36Å; Y573-L661 VanDerWaalsContact OH-CD1 3.23Å; Y573-L661 WeakPolarHBondContact OH-CD1 3.47Å
574G97.9Very high98.2Very high0 Ų049.6 Ų49.60%026%0.258CS..SBendtrans95.320.8-177.300000115.3S654 S657G574-S654 VanDerWaalsContact O-CA 3.31Å; G574-S654 WeakPolarHBondContact O-CA 3.48Å; G574-S657 WeakPolarHBondContact CA-OG 3.44Å; G574-S657 PolarHBondContact N-OG 3.16Å
575N98.1Very high98.2Very high21 Ų2150.4 Ų50.411%0.11226%0.264CS..SBendtrans-130.713.6-176.9-70.8-72.3000114.1K572 D577 A646 Q648 N649 S657K572-N575 PolarHBondContact O-ND2 2.55Å; N575-D577 VanDerWaalsContact C-N 3.3Å; N575-D577 PolarHBondContact O-N 3.37Å; N575-A646 PolarHBondContact ND2-O 3.49Å; N575-A646 PolarHBondContact OD1-O 2.97Å; N575-Q648 PolarHBondContact OD1-N 2.92Å; N575-N649 PolarHBondContact O-ND2 3.2Å; N575-N649 PolarHBondContact OD1-N 2.94Å; N575-S657 PolarHBondContact N-OG 2.91Å; N575-S657 VanDerWaalsContact N-OG 3.12Å
576D97.9Very high98.2Very high76 Ų7647.7 Ų47.741%0.40625%0.25SS..SBendtrans54.644.4-172.9-157.812.7000111.9A653 N656 S657D576-A653 HydrophobicContact CB-CB 4.31Å; D576-A653 PolarHBondContact N-O 2.69Å; D576-N656 HydrophobicContact CB-CB 4.08Å; D576-N656 PolarHBondContact OD2-ND2 3.49Å; D576-N656 VanDerWaalsContact OD2-ND2 3.08Å; D576-S657 WeakPolarHBondContact CA-OG 2.7Å; D576-S657 PolarHBondContact N-OG 3.19Å
577D98.3Very high98.2Very high42 Ų4245.3 Ų45.323%0.22524%0.238CC..  trans-115.1105.6178.3-167.6-38.1000110P571 N575 R579 A580 D581P571-D577 HydrophobicContact CB-CB 4.37Å; N575-D577 VanDerWaalsContact C-N 3.3Å; N575-D577 PolarHBondContact O-N 3.37Å; D577-R579 PolarHBondContact O-N 3.13Å; D577-R579 VanDerWaalsContact OD1-CB 3.22Å; D577-R579 WeakPolarHBondContact OD1-CB 3.38Å; D577-R579 WeakPolarHBondContact OD1-CG 3.28Å; D577-R579 IonicContact OD1-CZ 3.86Å; D577-R579 PolarHBondContact OD1-N 3.49Å; D577-R579 IonicContact OD1-NE 3.49Å; D577-R579 PolarHBondContact OD1-NE 2.91Å; D577-R579 IonicContact OD1-NH2 3.91Å; D577-R579 IonicContact OD2-CZ 3.34Å; D577-R579 IonicContact OD2-NE 2.98Å; D577-R579 PolarHBondContact OD2-NE 3.18Å; D577-R579 IonicContact OD2-NH2 2.66Å; D577-R579 PolarHBondContact OD2-NH2 3.48Å; D577-A580 PolarHBondContact O-N 2.71Å; D577-D581 PolarHBondContact N-OD2 3.43Å; D577-D581 PolarHBondContact O-N 2.79Å
578A98.2Very high98.2Very high58 Ų5841 Ų4148%0.47922%0.215SC..Hα-helixtrans-51.3-28.3-178.200000113.4A580 D581 D582A578-A580 VanDerWaalsContact C-N 3.3Å; A578-A580 PolarHBondContact O-N 2.84Å; A578-D581 PolarHBondContact O-N 3.3Å; A578-D582 WeakPolarHBondContact O-CB 3.19Å; A578-D582 PolarHBondContact O-N 3.26Å
579R98.5Very high98.3Very high115 Ų11542 Ų4243%0.43421%0.207SC..Hα-helixtrans-62.9-35.2179.3-63.1177.7-67.1164.8-3.1113.1Y548 P571 D577Y548-R579 HydrophobicContact CE1-CG 4.42Å; Y548-R579 HydrophobicContact CE2-CB 3.79Å; P571-R579 HydrophobicContact CB-CB 4.21Å; P571-R579 HydrophobicContact CG-CB 3.68Å; D577-R579 PolarHBondContact O-N 3.13Å; D577-R579 VanDerWaalsContact OD1-CB 3.22Å; D577-R579 WeakPolarHBondContact OD1-CB 3.38Å; D577-R579 WeakPolarHBondContact OD1-CG 3.28Å; D577-R579 IonicContact OD1-CZ 3.86Å; D577-R579 PolarHBondContact OD1-N 3.49Å; D577-R579 IonicContact OD1-NE 3.49Å; D577-R579 PolarHBondContact OD1-NE 2.91Å; D577-R579 IonicContact OD1-NH2 3.91Å; D577-R579 IonicContact OD2-CZ 3.34Å; D577-R579 IonicContact OD2-NE 2.98Å; D577-R579 PolarHBondContact OD2-NE 3.18Å; D577-R579 IonicContact OD2-NH2 2.66Å; D577-R579 PolarHBondContact OD2-NH2 3.48Å
580A98.6Very high98.4Very high0 Ų033.9 Ų33.90%017%0.17CC..Hα-helixtrans-91.6-4017500000111V540 P571 D577 A578 D582 L583 A584V540-A580 HydrophobicContact CG1-CB 4.36Å; V540-A580 WeakPolarHBondContact CG1-O 3.24Å; P571-A580 HydrophobicContact CB-CB 4.24Å; D577-A580 PolarHBondContact O-N 2.71Å; A578-A580 VanDerWaalsContact C-N 3.3Å; A578-A580 PolarHBondContact O-N 2.84Å; A580-D582 VanDerWaalsContact C-N 3.33Å; A580-D582 PolarHBondContact O-N 2.82Å; A580-L583 WeakPolarHBondContact O-CB 3.38Å; A580-L583 PolarHBondContact O-N 2.92Å; A580-L583 VanDerWaalsContact O-N 3.07Å; A580-A584 PolarHBondContact O-N 2.77Å
581D98.6Very high98.4Very high2 Ų232.4 Ų32.41%0.01116%0.163CC..Hα-helixtrans-65.7-35.4-176.7-61-13000112Y573 D577 A578 L583 A584 V585 S657 K660Y573-D581 WeakPolarHBondContact CD2-OD1 3.41Å; D577-D581 PolarHBondContact N-OD2 3.43Å; D577-D581 PolarHBondContact O-N 2.79Å; A578-D581 PolarHBondContact O-N 3.3Å; D581-L583 VanDerWaalsContact C-N 3.3Å; D581-L583 PolarHBondContact O-N 2.78Å; D581-A584 VanDerWaalsContact O-CB 3.26Å; D581-A584 WeakPolarHBondContact O-CB 3.23Å; D581-A584 PolarHBondContact O-N 2.66Å; D581-A584 VanDerWaalsContact O-N 3.12Å; D581-V585 WeakPolarHBondContact O-CG2 3.44Å; D581-V585 PolarHBondContact O-N 3.35Å; D581-S657 VanDerWaalsContact CG-OG 3.23Å; D581-S657 WeakPolarHBondContact OD1-CB 3.45Å; D581-S657 PolarHBondContact OD1-OG 2.62Å; D581-S657 WeakPolarHBondContact OD2-CA 3.29Å; D581-S657 WeakPolarHBondContact OD2-CB 3.26Å; D581-S657 PolarHBondContact OD2-OG 3.3Å; D581-K660 HydrophobicContact CB-CB 4.38Å; D581-K660 HydrophobicContact CB-CG 4.05Å
582D98.7Very high98.4Very high111 Ų11132.4 Ų32.459%0.59416%0.162SC*.Hα-helixtrans-65.3-33.3174.1-71.6-17.7000112A578 A580 V585 W586A578-D582 WeakPolarHBondContact O-CB 3.19Å; A578-D582 PolarHBondContact O-N 3.26Å; A580-D582 VanDerWaalsContact C-N 3.33Å; A580-D582 PolarHBondContact O-N 2.82Å; D582-V585 PolarHBondContact O-N 3.42Å; D582-W586 PolarHBondContact O-N 3.33Å
583L98.7Very high98.4Very high10 Ų1034 Ų345%0.05217%0.171CC..Hα-helixtrans-68.8-36.6172.9-68.1171.4000110.8F479 V540 L543 A544 A580 D581 W586 V587F479-L583 HydrophobicContact CE2-CD2 4.24Å; F479-L583 HydrophobicContact CZ-CD2 3.96Å; V540-L583 HydrophobicContact CG1-CB 4.1Å; L543-L583 HydrophobicContact CB-CD1 4.07Å; A544-L583 HydrophobicContact CB-CD1 3.9Å; A580-L583 WeakPolarHBondContact O-CB 3.38Å; A580-L583 PolarHBondContact O-N 2.92Å; A580-L583 VanDerWaalsContact O-N 3.07Å; D581-L583 VanDerWaalsContact C-N 3.3Å; D581-L583 PolarHBondContact O-N 2.78Å; L583-W586 PolarHBondContact O-N 3.38Å; L583-V587 WeakPolarHBondContact O-CG2 3.19Å; L583-V587 PolarHBondContact O-N 3.2Å
584A98.7Very high98.4Very high1 Ų134.5 Ų34.51%0.00817%0.173CC..Hα-helixtrans-59.9-47.1173.400000111.6F536 V540 Y573 A580 D581 W586 V587 L588 L661F536-A584 HydrophobicContact CE1-CB 3.83Å; F536-A584 HydrophobicContact CZ-CB 3.75Å; F536-A584 VanDerWaalsContact CZ-O 3.23Å; F536-A584 WeakPolarHBondContact CZ-O 3.5Å; V540-A584 HydrophobicContact CG1-CB 4.11Å; V540-A584 VanDerWaalsContact CG2-CA 3.43Å; V540-A584 HydrophobicContact CG2-CB 3.71Å; Y573-A584 HydrophobicContact CD2-CB 3.92Å; Y573-A584 HydrophobicContact CE2-CB 3.85Å; A580-A584 PolarHBondContact O-N 2.77Å; D581-A584 VanDerWaalsContact O-CB 3.26Å; D581-A584 WeakPolarHBondContact O-CB 3.23Å; D581-A584 PolarHBondContact O-N 2.66Å; D581-A584 VanDerWaalsContact O-N 3.12Å; A584-W586 VanDerWaalsContact C-N 3.32Å; A584-W586 PolarHBondContact O-N 2.94Å; A584-V587 PolarHBondContact O-N 3.12Å; A584-L588 PolarHBondContact O-N 3.15Å; A584-L588 VanDerWaalsContact O-N 3.16Å; A584-L661 HydrophobicContact CB-CD2 3.88Å
585V98.7Very high98.5Very high29 Ų2934.5 Ų34.518%0.17617%0.173CC..Hα-helixtrans-60.2-42.8174.8177.30000111.1D581 D582 L588 K589 K660 P662D581-V585 WeakPolarHBondContact O-CG2 3.44Å; D581-V585 PolarHBondContact O-N 3.35Å; D582-V585 PolarHBondContact O-N 3.42Å; V585-L588 PolarHBondContact O-N 2.99Å; V585-K589 HydrophobicContact CG1-CD 4Å; V585-K589 HydrophobicContact CG1-CG 4.33Å; V585-K589 WeakPolarHBondContact O-CG 3.24Å; V585-K589 PolarHBondContact O-N 3.38Å; V585-K660 HydrophobicContact CG2-CB 4.39Å; V585-K660 VanDerWaalsContact CG2-O 3.29Å; V585-K660 WeakPolarHBondContact CG2-O 3.18Å; V585-P662 HydrophobicContact CG1-CG 4.33Å
586W98.3Very high98.4Very high74 Ų7439.1 Ų39.128%0.2819%0.194SC..Hα-helixtrans-61.1-46.7177.5179.986.4000112.4M483 Y486 L543 D582 L583 A584 L588 K589 T590M483-W586 HydrophobicContact CE-CD2 3.63Å; M483-W586 HydrophobicContact CE-CE3 3.72Å; M483-W586 HydrophobicContact CE-CG 4.48Å; M483-W586 HydrophobicContact CE-CH2 3.42Å; M483-W586 VanDerWaalsContact CE-CH2 3.42Å; M483-W586 HydrophobicContact CE-CZ2 3.3Å; M483-W586 HydrophobicContact CE-CZ3 3.63Å; M483-W586 HydrophobicContact SD-CE3 4.42Å; M483-W586 HydrophobicContact SD-CH2 4.03Å; M483-W586 HydrophobicContact SD-CZ2 4.47Å; M483-W586 HydrophobicContact SD-CZ3 4Å; Y486-W586 HydrophobicContact CD1-CH2 4.2Å; Y486-W586 HydrophobicContact CD1-CZ3 4.06Å; Y486-W586 HydrophobicContact CE1-CZ3 4.2Å; L543-W586 HydrophobicContact CD1-CE3 4.39Å; L543-W586 HydrophobicContact CD1-CZ3 4.19Å; D582-W586 PolarHBondContact O-N 3.33Å; L583-W586 PolarHBondContact O-N 3.38Å; A584-W586 VanDerWaalsContact C-N 3.32Å; A584-W586 PolarHBondContact O-N 2.94Å; W586-L588 VanDerWaalsContact C-N 3.34Å; W586-L588 PolarHBondContact O-N 3.25Å; W586-K589 PolarHBondContact O-N 3.37Å; W586-T590 HydrophobicContact CH2-CG2 4.09Å; W586-T590 HydrophobicContact CZ2-CG2 3.82Å; W586-T590 PolarHBondContact NE1-OG1 3.38Å; W586-T590 WeakPolarHBondContact O-CB 3.47Å; W586-T590 PolarHBondContact O-N 3.4Å; W586-T590 PolarHBondContact O-OG1 3.44Å
587V98.7Very high98.5Very high0 Ų041.3 Ų41.30%020%0.202CC..Hα-helixtrans-59.1-46.3-179.6171.40000110.7L444 F536 V539 V540 L543 L583 A584 F591L444-V587 HydrophobicContact CD2-CG1 3.97Å; F536-V587 HydrophobicContact CD2-CG1 3.89Å; F536-V587 HydrophobicContact CE2-CB 3.98Å; F536-V587 HydrophobicContact CE2-CG1 3.81Å; V539-V587 HydrophobicContact CG1-CG1 4.35Å; V539-V587 HydrophobicContact CG1-CG2 3.78Å; V540-V587 HydrophobicContact CG2-CG2 4.29Å; L543-V587 HydrophobicContact CD1-CG2 4.05Å; L583-V587 WeakPolarHBondContact O-CG2 3.19Å; L583-V587 PolarHBondContact O-N 3.2Å; A584-V587 PolarHBondContact O-N 3.12Å; V587-F591 WeakPolarHBondContact O-CB 3.43Å; V587-F591 PolarHBondContact O-N 3Å; V587-F591 VanDerWaalsContact O-N 3.16Å
588L98.6Very high98.5Very high0 Ų042.2 Ų42.20%020%0.202CC..Hα-helixtrans-62.4-53.9179.717359.1000111.6I533 F536 A584 V585 W586 T590 F591 M592 T608 I610 P662 A666I533-L588 HydrophobicContact CD1-CD1 4.16Å; F536-L588 HydrophobicContact CE2-CB 4.16Å; A584-L588 PolarHBondContact O-N 3.15Å; A584-L588 VanDerWaalsContact O-N 3.16Å; V585-L588 PolarHBondContact O-N 2.99Å; W586-L588 VanDerWaalsContact C-N 3.34Å; W586-L588 PolarHBondContact O-N 3.25Å; L588-T590 PolarHBondContact O-N 2.96Å; L588-F591 PolarHBondContact O-N 3Å; L588-M592 PolarHBondContact O-N 3Å; L588-M592 VanDerWaalsContact O-N 3.08Å; L588-T608 HydrophobicContact CD1-CG2 3.8Å; L588-I610 HydrophobicContact CD1-CD1 4.26Å; L588-I610 HydrophobicContact CD1-CG1 4.29Å; L588-I610 HydrophobicContact CD2-CD1 4.29Å; L588-P662 HydrophobicContact CD2-CG 4.29Å; L588-A666 HydrophobicContact CD1-CB 3.95Å; L588-A666 HydrophobicContact CD2-CB 4.04Å
589K98.4Very high98.5Very high65 Ų6545.5 Ų45.528%0.28321%0.208SC..Hα-helixtrans-60.6-47.5-177.1-70.5-171.4177.9-169.90111.8V585 W586 F591 M592 E593 Y665V585-K589 HydrophobicContact CG1-CD 4Å; V585-K589 HydrophobicContact CG1-CG 4.33Å; V585-K589 WeakPolarHBondContact O-CG 3.24Å; V585-K589 PolarHBondContact O-N 3.38Å; W586-K589 PolarHBondContact O-N 3.37Å; K589-F591 VanDerWaalsContact C-N 3.34Å; K589-F591 PolarHBondContact O-N 2.72Å; K589-M592 PolarHBondContact O-N 2.94Å; K589-E593 WeakPolarHBondContact O-CG 3.31Å; K589-E593 PolarHBondContact O-N 2.99Å; K589-Y665 HydrophobicContact CB-CD1 4.21Å; K589-Y665 HydrophobicContact CB-CE1 4.32Å; K589-Y665 HydrophobicContact CD-CD2 4.38Å; K589-Y665 HydrophobicContact CD-CE1 4.14Å; K589-Y665 HydrophobicContact CD-CE2 4.07Å; K589-Y665 VanDerWaalsContact CE-CE2 3.4Å; K589-Y665 HydrophobicContact CG-CD1 3.77Å; K589-Y665 HydrophobicContact CG-CD2 4Å; K589-Y665 HydrophobicContact CG-CE1 3.87Å; K589-Y665 HydrophobicContact CG-CE2 4.15Å; K589-Y665 HydrophobicContact CG-CG 3.82Å
590T98.4Very high98.5Very high9 Ų940.4 Ų40.46%0.05519%0.189CC..Hα-helixtrans-61.2-43.2-177.6-570000111.4L490 W586 L588 K594L490-T590 HydrophobicContact CD1-CG2 4.25Å; W586-T590 HydrophobicContact CH2-CG2 4.09Å; W586-T590 HydrophobicContact CZ2-CG2 3.82Å; W586-T590 PolarHBondContact NE1-OG1 3.38Å; W586-T590 WeakPolarHBondContact O-CB 3.47Å; W586-T590 PolarHBondContact O-N 3.4Å; W586-T590 PolarHBondContact O-OG1 3.44Å; L588-T590 PolarHBondContact O-N 2.96Å; T590-K594 HydrophobicContact CG2-CD 4.15Å; T590-K594 VanDerWaalsContact CG2-CE 3.43Å; T590-K594 WeakPolarHBondContact O-CD 3.43Å; T590-K594 WeakPolarHBondContact O-CG 3.29Å; T590-K594 PolarHBondContact O-N 3.34Å
591F98.6Very high98.5Very high0 Ų041.6 Ų41.60%019%0.194CC..Hα-helixtrans-69.6-39.1179.2-166.3-117.6000112.1A442 L444 L490 L493 A494 Y497 I533 V587 L588 K589 K594 L595A442-F591 HydrophobicContact CB-CZ 4.45Å; L444-F591 HydrophobicContact CD1-CD1 4.4Å; L444-F591 HydrophobicContact CD1-CE1 4.09Å; L444-F591 HydrophobicContact CD1-CE2 4.33Å; L444-F591 HydrophobicContact CD1-CZ 4.05Å; L444-F591 HydrophobicContact CD2-CB 4.36Å; L444-F591 HydrophobicContact CD2-CD1 4.41Å; L444-F591 HydrophobicContact CD2-CD2 4.44Å; L444-F591 HydrophobicContact CD2-CG 4.16Å; L490-F591 HydrophobicContact CB-CD2 4.45Å; L490-F591 HydrophobicContact CD2-CD2 3.88Å; L490-F591 HydrophobicContact CD2-CE2 4.25Å; L493-F591 HydrophobicContact CD2-CE2 4.1Å; L493-F591 HydrophobicContact CD2-CZ 4.33Å; L493-F591 HydrophobicContact CG-CE2 4.2Å; L493-F591 HydrophobicContact CG-CZ 4.38Å; A494-F591 HydrophobicContact CB-CE2 4.36Å; Y497-F591 HydrophobicContact CD1-CZ 4.38Å; I533-F591 HydrophobicContact CD1-CB 4.44Å; I533-F591 HydrophobicContact CD1-CD1 3.82Å; I533-F591 HydrophobicContact CG1-CD1 3.65Å; I533-F591 HydrophobicContact CG1-CE1 3.99Å; V587-F591 WeakPolarHBondContact O-CB 3.43Å; V587-F591 PolarHBondContact O-N 3Å; V587-F591 VanDerWaalsContact O-N 3.16Å; L588-F591 PolarHBondContact O-N 3Å; K589-F591 VanDerWaalsContact C-N 3.34Å; K589-F591 PolarHBondContact O-N 2.72Å; F591-K594 PolarHBondContact O-N 2.9Å; F591-L595 HydrophobicContact CD1-CD1 3.83Å; F591-L595 HydrophobicContact CD1-CG 4.41Å; F591-L595 HydrophobicContact CE1-CD1 3.81Å; F591-L595 HydrophobicContact CE1-CD2 4.38Å; F591-L595 HydrophobicContact CE1-CG 4.25Å; F591-L595 HydrophobicContact CZ-CD2 4.31Å; F591-L595 HydrophobicContact CZ-CG 4.49Å; F591-L595 VanDerWaalsContact O-CG 3.28Å; F591-L595 WeakPolarHBondContact O-CG 3.5Å; F591-L595 PolarHBondContact O-N 2.98Å; F591-L595 VanDerWaalsContact O-N 3.08Å
592M98.4Very high98.4Very high7 Ų743.4 Ų43.43%0.03420%0.201CC..Hα-helixtrans-61.6-47.8175.5-171.762.2-128.100111.9L588 K589 K594 L595 E596 P606 T608L588-M592 PolarHBondContact O-N 3Å; L588-M592 VanDerWaalsContact O-N 3.08Å; K589-M592 PolarHBondContact O-N 2.94Å; M592-K594 VanDerWaalsContact C-N 3.28Å; M592-K594 PolarHBondContact O-N 3.24Å; M592-L595 HydrophobicContact CE-CB 4.49Å; M592-L595 WeakPolarHBondContact O-CB 3.2Å; M592-L595 PolarHBondContact O-N 3.47Å; M592-L595 VanDerWaalsContact O-N 3.09Å; M592-L595 HydrophobicContact SD-CD1 4.48Å; M592-E596 HydrophobicContact CE-CG 3.73Å; M592-E596 PolarHBondContact O-N 2.85Å; M592-P606 HydrophobicContact CE-CB 3.95Å; M592-P606 HydrophobicContact CE-CG 4.2Å; M592-P606 VanDerWaalsContact CE-O 3.27Å; M592-P606 WeakPolarHBondContact CE-O 3.5Å; M592-T608 HydrophobicContact CB-CG2 4.25Å; M592-T608 HydrophobicContact CG-CG2 4.41Å; M592-T608 HydrophobicContact SD-CG2 3.64Å
593E98.3Very high98.3Very high95 Ų9543.6 Ų43.644%0.44420%0.201SC..Hα-helixtrans-56.7-41.7177-73.4172.3-178.600111.8K589 L595 E596 H597K589-E593 WeakPolarHBondContact O-CG 3.31Å; K589-E593 PolarHBondContact O-N 2.99Å; E593-L595 PolarHBondContact O-N 2.89Å; E593-E596 WeakPolarHBondContact O-CB 3.49Å; E593-E596 PolarHBondContact O-N 3.47Å; E593-H597 PolarHBondContact O-CD2 2.82Å
594K98.6Very high98.3Very high10 Ų1043.3 Ų43.34%0.04320%0.2CC..Hα-helixtrans-66.8-36.4177.6-68.2172.1-179.4-68.10112.8D487 L490 E491 A494 T590 F591 M592 E596 H597 Y598D487-K594 WeakPolarHBondContact O-CE 3.39Å; D487-K594 PolarHBondContact O-NZ 3.45Å; D487-K594 WeakPolarHBondContact OD1-CE 3.41Å; D487-K594 IonicContact OD1-NZ 3.7Å; D487-K594 PolarHBondContact OD1-NZ 2.82Å; D487-K594 IonicContact OD2-NZ 2.67Å; D487-K594 PolarHBondContact OD2-NZ 3.46Å; L490-K594 HydrophobicContact CB-CD 3.54Å; E491-K594 HydrophobicContact CB-CD 4.47Å; E491-K594 WeakPolarHBondContact OE2-CG 3.38Å; E491-K594 IonicContact OE2-NZ 3.43Å; A494-K594 HydrophobicContact CB-CB 3.88Å; T590-K594 HydrophobicContact CG2-CD 4.15Å; T590-K594 VanDerWaalsContact CG2-CE 3.43Å; T590-K594 WeakPolarHBondContact O-CD 3.43Å; T590-K594 WeakPolarHBondContact O-CG 3.29Å; T590-K594 PolarHBondContact O-N 3.34Å; F591-K594 PolarHBondContact O-N 2.9Å; M592-K594 VanDerWaalsContact C-N 3.28Å; M592-K594 PolarHBondContact O-N 3.24Å; K594-E596 VanDerWaalsContact C-N 3.26Å; K594-E596 PolarHBondContact O-N 3.06Å; K594-H597 WeakPolarHBondContact O-CB 3.29Å; K594-H597 PolarHBondContact O-N 2.97Å; K594-Y598 VanDerWaalsContact O-CD2 3.25Å; K594-Y598 WeakPolarHBondContact O-CD2 3.41Å; K594-Y598 WeakPolarHBondContact O-CE2 3.29Å
595L98.6Very high98.2Very high0 Ų047.1 Ų47.10%022%0.218CC..Hα-helixtrans-63.4-35175.4-70.4164.6000111.8A494 V498 T531 F591 M592 E593 H597 Y598A494-L595 HydrophobicContact CB-CD2 3.97Å; A494-L595 HydrophobicContact CB-CG 4.33Å; V498-L595 HydrophobicContact CG2-CD2 3.8Å; T531-L595 HydrophobicContact CG2-CD1 4.32Å; T531-L595 HydrophobicContact CG2-CD2 3.92Å; T531-L595 WeakPolarHBondContact OG1-CD1 3.22Å; F591-L595 HydrophobicContact CD1-CD1 3.83Å; F591-L595 HydrophobicContact CD1-CG 4.41Å; F591-L595 HydrophobicContact CE1-CD1 3.81Å; F591-L595 HydrophobicContact CE1-CD2 4.38Å; F591-L595 HydrophobicContact CE1-CG 4.25Å; F591-L595 HydrophobicContact CZ-CD2 4.31Å; F591-L595 HydrophobicContact CZ-CG 4.49Å; F591-L595 VanDerWaalsContact O-CG 3.28Å; F591-L595 WeakPolarHBondContact O-CG 3.5Å; F591-L595 PolarHBondContact O-N 2.98Å; F591-L595 VanDerWaalsContact O-N 3.08Å; M592-L595 HydrophobicContact CE-CB 4.49Å; M592-L595 WeakPolarHBondContact O-CB 3.2Å; M592-L595 PolarHBondContact O-N 3.47Å; M592-L595 VanDerWaalsContact O-N 3.09Å; M592-L595 HydrophobicContact SD-CD1 4.48Å; E593-L595 PolarHBondContact O-N 2.89Å; L595-H597 PolarHBondContact O-N 2.9Å; L595-Y598 PolarHBondContact O-N 3.39Å
596E97.9Very high98.2Very high117 Ų11747.1 Ų47.155%0.54722%0.219SC..Hα-helixtrans-67-17.6177.4-66.1175.1176.300113.7M592 E593 K594 Y598 P606M592-E596 HydrophobicContact CE-CG 3.73Å; M592-E596 PolarHBondContact O-N 2.85Å; E593-E596 WeakPolarHBondContact O-CB 3.49Å; E593-E596 PolarHBondContact O-N 3.47Å; K594-E596 VanDerWaalsContact C-N 3.26Å; K594-E596 PolarHBondContact O-N 3.06Å; E596-Y598 PolarHBondContact O-N 3.47Å; E596-P606 HydrophobicContact CG-CG 3.89Å
597H98.2Very high98.2Very high123 Ų12343.8 Ų43.857%0.56921%0.206SC*.THydrogen-bonded Turntrans-68.3-21175.9-61.9166.6000113.4E491 E593 K594 L595E491-H597 IonicContact OE1-ND1 3.41Å; E491-H597 PolarHBondContact OE1-ND1 3.47Å; E491-H597 IonicContact OE2-CE1 3.4Å; E491-H597 PolarHBondContact OE2-CE1 2.97Å; E491-H597 IonicContact OE2-ND1 2.69Å; E491-H597 PolarHBondContact OE2-ND1 3.23Å; E593-H597 PolarHBondContact O-CD2 2.82Å; K594-H597 WeakPolarHBondContact O-CB 3.29Å; K594-H597 PolarHBondContact O-N 2.97Å; L595-H597 PolarHBondContact O-N 2.9Å
598Y98.5Very high98.2Very high61 Ų6143.8 Ų43.824%0.23921%0.206CC..SBendtrans-105.3141-170.1-64.1-87000112.6E491 A494 V498 K594 L595 E596E491-Y598 PolarHBondContact O-OH 3.24Å; E491-Y598 VanDerWaalsContact O-OH 3.06Å; E491-Y598 VanDerWaalsContact OE1-CE2 3.26Å; E491-Y598 WeakPolarHBondContact OE1-CE2 3Å; E491-Y598 VanDerWaalsContact OE1-CZ 3.28Å; E491-Y598 PolarHBondContact OE1-OH 2.92Å; A494-Y598 HydrophobicContact CB-CD2 4.19Å; A494-Y598 HydrophobicContact CB-CE2 3.87Å; V498-Y598 HydrophobicContact CB-CG 4.48Å; K594-Y598 VanDerWaalsContact O-CD2 3.25Å; K594-Y598 WeakPolarHBondContact O-CD2 3.41Å; K594-Y598 WeakPolarHBondContact O-CE2 3.29Å; L595-Y598 PolarHBondContact O-N 3.39Å; E596-Y598 PolarHBondContact O-N 3.47Å
599H98.2Very high98.2Very high127 Ų12743.9 Ų43.959%0.58821%0.207SC*.  trans-67.9135.8173.2173.572.5000111.4V498 N502 N603V498-H599 WeakPolarHBondContact CG1-O 3.37Å; N502-H599 PolarHBondContact ND2-O 3.06Å; H599-N603 PolarHBondContact CE1-OD1 3.48Å
600T98.7Very high98.2Very high8 Ų840.8 Ų40.85%0.04919%0.193CC..  trans-111.5143179.6540000111.3V498 N502 F529 R602 N603 S604 P606V498-T600 HydrophobicContact CG1-CG2 4.15Å; N502-T600 WeakPolarHBondContact OD1-CA 3.4Å; F529-T600 HydrophobicContact CB-CG2 3.89Å; F529-T600 HydrophobicContact CD1-CG2 3.83Å; F529-T600 HydrophobicContact CD2-CG2 4.06Å; F529-T600 HydrophobicContact CE1-CG2 4.25Å; F529-T600 HydrophobicContact CE2-CG2 4.45Å; F529-T600 HydrophobicContact CG-CG2 3.68Å; F529-T600 HydrophobicContact CZ-CG2 4.5Å; T600-R602 PolarHBondContact O-N 3.22Å; T600-N603 WeakPolarHBondContact O-CA 3.14Å; T600-N603 PolarHBondContact O-N 3.49Å; T600-S604 WeakPolarHBondContact CB-O 3.33Å; T600-S604 WeakPolarHBondContact CB-OG 3.43Å; T600-S604 PolarHBondContact OG1-N 3.4Å; T600-S604 PolarHBondContact OG1-O 3.38Å; T600-S604 PolarHBondContact OG1-OG 3.31Å; T600-P606 HydrophobicContact CG2-CB 4.44Å
601Y98.5Very high98.2Very high24 Ų2440.5 Ų40.59%0.09419%0.191CC..G310 helixtrans-57135.4-179170-112.2000112.1F437 N502 H505 Y506 D509 N603 S604F437-Y601 HydrophobicContact CD2-CD1 4.3Å; F437-Y601 AromaticContact CE2-CD1 3.49Å; F437-Y601 HydrophobicContact CE2-CD1 3.49Å; F437-Y601 VanDerWaalsContact CE2-CD1 3.49Å; F437-Y601 AromaticContact CE2-CE1 3.93Å; F437-Y601 HydrophobicContact CE2-CE1 3.93Å; F437-Y601 AromaticContact CZ-CD1 3.76Å; F437-Y601 HydrophobicContact CZ-CD1 3.76Å; F437-Y601 AromaticContact CZ-CE1 3.69Å; F437-Y601 HydrophobicContact CZ-CE1 3.69Å; N502-Y601 WeakPolarHBondContact OD1-CB 3.5Å; N502-Y601 PolarHBondContact OD1-N 3.49Å; H505-Y601 HydrophobicContact CB-CD1 3.63Å; H505-Y601 HydrophobicContact CB-CE1 4.14Å; Y506-Y601 HydrophobicContact CD2-CD2 4.09Å; Y506-Y601 AromaticContact CD2-CE2 3.53Å; Y506-Y601 HydrophobicContact CD2-CE2 3.53Å; Y506-Y601 HydrophobicContact CE2-CE2 4.46Å; Y506-Y601 HydrophobicContact CG-CE2 4.19Å; D509-Y601 VanDerWaalsContact OD2-CE1 3.25Å; D509-Y601 WeakPolarHBondContact OD2-CE1 3.42Å; D509-Y601 PolarHBondContact OD2-OH 3.06Å; Y601-N603 PolarHBondContact O-N 3.35Å; Y601-S604 PolarHBondContact O-N 2.93Å; Y601-S604 PolarHBondContact O-OG 2.7Å
602R97Very high98Very high41 Ų4140.5 Ų40.516%0.15519%0.191CC..G310 helixtrans55.228.9-172.2-63.8179.895.4156.84.9114E229 F437 D509 T600 S604E229-R602 IonicContact OE1-CZ 3.24Å; E229-R602 IonicContact OE1-NH1 2.76Å; E229-R602 PolarHBondContact OE1-NH1 2.86Å; E229-R602 IonicContact OE1-NH2 3.15Å; E229-R602 PolarHBondContact OE1-NH2 3.12Å; E229-R602 VanDerWaalsContact OE1-NH2 3.15Å; E229-R602 IonicContact OE2-CZ 3.67Å; E229-R602 IonicContact OE2-NH1 2.65Å; E229-R602 IonicContact OE2-NH2 2.86Å; E229-R602 PolarHBondContact OE2-NH2 3Å; F437-R602 HydrophobicContact CE2-CB 4.43Å; D509-R602 WeakPolarHBondContact OD2-CD 3.34Å; D509-R602 IonicContact OD2-CZ 3.14Å; D509-R602 IonicContact OD2-NE 2.7Å; D509-R602 IonicContact OD2-NH1 3.04Å; D509-R602 PolarHBondContact OD2-NH1 3.46Å; T600-R602 PolarHBondContact O-N 3.22Å; R602-S604 PolarHBondContact O-N 3.21Å
603N96.6Very high97.7Very high114 Ų11440.3 Ų40.361%0.6119%0.191SC*.G310 helixtrans53.935.6178.9-53.7-57.8000112.5H599 T600 Y601H599-N603 PolarHBondContact CE1-OD1 3.48Å; T600-N603 WeakPolarHBondContact O-CA 3.14Å; T600-N603 PolarHBondContact O-N 3.49Å; Y601-N603 PolarHBondContact O-N 3.35Å
604S97.9Very high97.3Very high4 Ų436 Ų363%0.02817%0.171CC..PPolyproline II helixtrans-69.4142.9179.749.40000111.9R527 F529 T600 Y601 R602 P606R527-S604 CarbonylContact O-C 3.14Å; R527-S604 WeakPolarHBondContact O-CA 3.08Å; R527-S604 VanDerWaalsContact O-CB 3.29Å; R527-S604 WeakPolarHBondContact O-CB 3.42Å; F529-S604 WeakPolarHBondContact CB-OG 3.49Å; F529-S604 WeakPolarHBondContact CD2-OG 3.48Å; T600-S604 WeakPolarHBondContact CB-O 3.33Å; T600-S604 WeakPolarHBondContact CB-OG 3.43Å; T600-S604 PolarHBondContact OG1-N 3.4Å; T600-S604 PolarHBondContact OG1-O 3.38Å; T600-S604 PolarHBondContact OG1-OG 3.31Å; Y601-S604 PolarHBondContact O-N 2.93Å; Y601-S604 PolarHBondContact O-OG 2.7Å; R602-S604 PolarHBondContact O-N 3.21Å; S604-P606 WeakPolarHBondContact O-CD 3.33Å
605E97.6Very high97.1Very high81 Ų8135.6 Ų35.638%0.37917%0.169SC..EExtended strand (participates in β ladder)trans-69.7119.4179.8-179.2177.7-170.400110.8K526 R527 T528 F529 T607K526-E605 WeakPolarHBondContact CE-OE2 3.45Å; K526-E605 IonicContact NZ-OE2 2.76Å; K526-E605 PolarHBondContact NZ-OE2 3.36Å; R527-E605 PolarHBondContact O-N 2.87Å; T528-E605 CarbonylContact C-O 3.52Å; T528-E605 WeakPolarHBondContact CA-O 3.46Å; T528-E605 WeakPolarHBondContact CB-O 3.31Å; T528-E605 HydrophobicContact CG2-CB 4.43Å; F529-E605 PolarHBondContact N-O 2.82Å; E605-T607 PolarHBondContact O-N 2.84Å
606P98.3Very high96.9Very high30 Ų3035.6 Ų35.620%0.19517%0.169CC..EExtended strand (participates in β ladder)trans-62134.4177.128.4-34.4000110.3M592 E596 T600 S604M592-P606 HydrophobicContact CE-CB 3.95Å; M592-P606 HydrophobicContact CE-CG 4.2Å; M592-P606 VanDerWaalsContact CE-O 3.27Å; M592-P606 WeakPolarHBondContact CE-O 3.5Å; E596-P606 HydrophobicContact CG-CG 3.89Å; T600-P606 HydrophobicContact CG2-CB 4.44Å; S604-P606 WeakPolarHBondContact O-CD 3.33Å
607T98.4Very high96.6Very high4 Ų430.4 Ų30.43%0.02515%0.145CC..EExtended strand (participates in β ladder)trans-135.8162.2171.1590000108.9T528 F529 A530 T531 E605 L667T528-T607 HydrophobicContact CG2-CG2 3.92Å; F529-T607 PolarHBondContact O-N 3.5Å; F529-T607 VanDerWaalsContact O-O 3.06Å; A530-T607 WeakPolarHBondContact CA-OG1 3.38Å; T531-T607 PolarHBondContact N-O 2.72Å; T531-T607 PolarHBondContact OG1-O 2.83Å; E605-T607 PolarHBondContact O-N 2.84Å; T607-L667 HydrophobicContact CG2-CB 4.01Å
608T98.6Very high96.4Very high0 Ų025.4 Ų25.40%012%0.124CC..EExtended strand (participates in β ladder)trans-133.8160173.2-163.30000111.3T531 I533 L588 M592 Y665 A666 D668T531-T608 CarbonylContact O-C 3.57Å; T531-T608 WeakPolarHBondContact O-CA 3.42Å; T531-T608 WeakPolarHBondContact OG1-CB 3.49Å; T531-T608 PolarHBondContact OG1-OG1 3.34Å; I533-T608 HydrophobicContact CD1-CG2 4.46Å; L588-T608 HydrophobicContact CD1-CG2 3.8Å; M592-T608 HydrophobicContact CB-CG2 4.25Å; M592-T608 HydrophobicContact CG-CG2 4.41Å; M592-T608 HydrophobicContact SD-CG2 3.64Å; T608-Y665 WeakPolarHBondContact CG2-O 3.27Å; T608-A666 CarbonylContact O-C 3.57Å; T608-A666 WeakPolarHBondContact O-CA 3.26Å; T608-D668 VanDerWaalsContact O-CB 3.27Å; T608-D668 WeakPolarHBondContact O-CB 3.41Å; T608-D668 PolarHBondContact O-N 3.24Å
609S98.6Very high96.4Very high1 Ų122.5 Ų22.51%0.00711%0.112CC..EExtended strand (participates in β ladder)trans-130.6154.6172.8510000111.2T531 G532 I533 D668 G669T531-S609 PolarHBondContact O-N 3.27Å; T531-S609 PolarHBondContact O-OG 3.15Å; G532-S609 CarbonylContact C-O 3.48Å; G532-S609 VanDerWaalsContact CA-O 3.31Å; G532-S609 WeakPolarHBondContact CA-O 3.18Å; I533-S609 PolarHBondContact N-O 3.32Å; S609-D668 WeakPolarHBondContact CB-OD2 3.33Å; S609-D668 PolarHBondContact OG-OD2 2.77Å; S609-D668 VanDerWaalsContact OG-OD2 3.07Å; S609-G669 CarbonylContact C-O 3.59Å; S609-G669 WeakPolarHBondContact CA-O 3.3Å; S609-G669 WeakPolarHBondContact CB-O 3.47Å
610I98.6Very high96.3Very high0 Ų016.5 Ų16.50%08%0.084CC..EExtended strand (participates in β ladder)trans-101.779.3165.1-46.6176.4000107.3I533 F536 L588 G639 A640 L661 G669 I670 S671I533-I610 HydrophobicContact CD1-CG1 4.45Å; F536-I610 HydrophobicContact CB-CG2 3.68Å; F536-I610 HydrophobicContact CD1-CD1 4.23Å; F536-I610 HydrophobicContact CD1-CG2 4.11Å; F536-I610 HydrophobicContact CD2-CD1 4.01Å; F536-I610 HydrophobicContact CD2-CG1 4.48Å; F536-I610 HydrophobicContact CD2-CG2 4.25Å; F536-I610 HydrophobicContact CE1-CD1 4Å; F536-I610 HydrophobicContact CE2-CD1 3.76Å; F536-I610 HydrophobicContact CG-CD1 4.23Å; F536-I610 HydrophobicContact CG-CG2 3.76Å; F536-I610 HydrophobicContact CZ-CD1 3.75Å; L588-I610 HydrophobicContact CD1-CD1 4.26Å; L588-I610 HydrophobicContact CD1-CG1 4.29Å; L588-I610 HydrophobicContact CD2-CD1 4.29Å; I610-G639 WeakPolarHBondContact CG2-O 3.49Å; I610-G639 WeakPolarHBondContact O-CA 3.42Å; I610-A640 HydrophobicContact CB-CB 3.96Å; I610-A640 HydrophobicContact CD1-CB 4.38Å; I610-A640 HydrophobicContact CG2-CB 3.62Å; I610-L661 HydrophobicContact CD1-CD1 3.93Å; I610-G669 PolarHBondContact N-O 3.35Å; I610-I670 HydrophobicContact CD1-CG1 4.45Å; I610-I670 HydrophobicContact CD1-CG2 4.37Å; I610-S671 PolarHBondContact O-N 3.28Å; I610-S671 VanDerWaalsContact O-N 3.08Å
611L97.7Very high96.2Very high3 Ų320 Ų202%0.01610%0.099CC..  trans-142.8126.5-170.8178.868.2000112.2C425 V426 R441 I613 S737C425-L611 HydrophobicContact CB-CD1 3.93Å; C425-L611 HydrophobicContact CB-CD2 4Å; V426-L611 HydrophobicContact CG2-CD1 4.38Å; V426-L611 HydrophobicContact CG2-CD2 4.17Å; R441-L611 PolarHBondContact NE-O 2.88Å; L611-I613 HydrophobicContact CD1-CD1 4.09Å; L611-I613 HydrophobicContact CG-CD1 4.45Å; L611-S737 WeakPolarHBondContact CD1-O 3.19Å
612T95.7Very high96.1Very high0 Ų019.6 Ų19.60%010%0.101CC..  trans-116.5-23.5-17561.10000115.3R441 A534 T614 S615 N616 P638 G639 S737R441-T612 PolarHBondContact NE-O 3.21Å; R441-T612 PolarHBondContact NH1-O 3.48Å; R441-T612 PolarHBondContact NH2-O 3.39Å; A534-T612 HydrophobicContact CB-CG2 3.86Å; T612-T614 PolarHBondContact O-N 3.32Å; T612-T614 VanDerWaalsContact O-N 3.11Å; T612-S615 WeakPolarHBondContact O-CB 3.47Å; T612-S615 PolarHBondContact O-N 2.72Å; T612-S615 PolarHBondContact O-OG 3.03Å; T612-N616 HydrophobicContact CG2-CB 4.28Å; T612-P638 VanDerWaalsContact OG1-CA 3.24Å; T612-P638 WeakPolarHBondContact OG1-CA 3.4Å; T612-G639 PolarHBondContact OG1-N 3.36Å; T612-S737 PolarHBondContact OG1-OG 3.13Å
613I91.1Very high96.2Very high4 Ų417.6 Ų17.62%0.0219%0.093CC..THydrogen-bonded Turntrans48.1-121.4-164.1-51.3-63000107.8F334 W340 C425 L611 N616 S737 Y739F334-I613 HydrophobicContact CD1-CB 4.24Å; F334-I613 HydrophobicContact CD1-CG1 4.32Å; F334-I613 HydrophobicContact CD1-CG2 3.8Å; F334-I613 HydrophobicContact CE1-CG1 4.4Å; W340-I613 HydrophobicContact CZ2-CD1 3.89Å; W340-I613 HydrophobicContact CZ2-CG1 4.23Å; W340-I613 HydrophobicContact CZ2-CG2 4.03Å; C425-I613 WeakPolarHBondContact SG-CD1 3.11Å; L611-I613 HydrophobicContact CD1-CD1 4.09Å; L611-I613 HydrophobicContact CG-CD1 4.45Å; I613-N616 PolarHBondContact O-OD1 3.47Å; I613-N616 VanDerWaalsContact O-OD1 3.06Å; I613-S737 WeakPolarHBondContact CA-OG 3.41Å; I613-S737 WeakPolarHBondContact CD1-O 3.38Å; I613-S737 PolarHBondContact N-OG 3.38Å; I613-S737 VanDerWaalsContact N-OG 3.14Å; I613-S737 PolarHBondContact O-OG 2.92Å; I613-Y739 HydrophobicContact CB-CE1 4.31Å; I613-Y739 HydrophobicContact CD1-CD1 3.76Å; I613-Y739 HydrophobicContact CD1-CE1 3.85Å; I613-Y739 HydrophobicContact CG2-CD1 4.39Å; I613-Y739 HydrophobicContact CG2-CE1 3.44Å; I613-Y739 VanDerWaalsContact CG2-CE1 3.44Å
614T90.9Very high96.3Very high5 Ų512.4 Ų12.43%0.0317%0.067CC..THydrogen-bonded Turntrans-1012.9178.2-30.40000112.3E332 L333 S335 T612 N616 V617 V618 Q750E332-T614 WeakPolarHBondContact O-CB 3.2Å; E332-T614 WeakPolarHBondContact O-CG2 3.08Å; L333-T614 WeakPolarHBondContact O-CB 3.44Å; L333-T614 PolarHBondContact O-N 3.07Å; L333-T614 PolarHBondContact O-OG1 3.06Å; S335-T614 WeakPolarHBondContact CB-OG1 3.4Å; S335-T614 PolarHBondContact N-OG1 3.34Å; S335-T614 WeakPolarHBondContact OG-CG2 3.19Å; S335-T614 PolarHBondContact OG-OG1 2.84Å; T612-T614 PolarHBondContact O-N 3.32Å; T612-T614 VanDerWaalsContact O-N 3.11Å; T614-N616 WeakPolarHBondContact CA-OD1 3.5Å; T614-N616 PolarHBondContact O-N 3.03Å; T614-N616 VanDerWaalsContact O-N 3.14Å; T614-V617 HydrophobicContact CG2-CB 4.32Å; T614-V617 HydrophobicContact CG2-CG2 4.14Å; T614-V617 PolarHBondContact O-N 2.79Å; T614-V618 PolarHBondContact O-N 2.99Å; T614-Q750 HydrophobicContact CG2-CG 4.27Å
615S92.9Very high96.3Very high0 Ų012.7 Ų12.70%07%0.068CC..Hα-helixtrans-65.4-14.5173.6-61.50000112.5L333 R441 T612 V617 V618 Y619L333-S615 WeakPolarHBondContact CD2-OG 3.41Å; R441-S615 VanDerWaalsContact CD-CB 3.5Å; R441-S615 WeakPolarHBondContact CD-OG 3.46Å; R441-S615 PolarHBondContact NH1-OG 2.9Å; T612-S615 WeakPolarHBondContact O-CB 3.47Å; T612-S615 PolarHBondContact O-N 2.72Å; T612-S615 PolarHBondContact O-OG 3.03Å; S615-V617 VanDerWaalsContact C-N 3.27Å; S615-V617 PolarHBondContact O-N 2.88Å; S615-V618 PolarHBondContact O-N 2.68Å; S615-Y619 WeakPolarHBondContact O-CB 3.46Å; S615-Y619 VanDerWaalsContact O-CD2 3.31Å; S615-Y619 WeakPolarHBondContact O-CD2 3.4Å; S615-Y619 PolarHBondContact O-N 3.47Å
616N94.2Very high96.3Very high0 Ų08.8 Ų8.80%05%0.05CC..Hα-helixtrans-60-40170.276.2-61.6000111T612 I613 T614 G620 L636 Y644 D753T612-N616 HydrophobicContact CG2-CB 4.28Å; I613-N616 PolarHBondContact O-OD1 3.47Å; I613-N616 VanDerWaalsContact O-OD1 3.06Å; T614-N616 WeakPolarHBondContact CA-OD1 3.5Å; T614-N616 PolarHBondContact O-N 3.03Å; T614-N616 VanDerWaalsContact O-N 3.14Å; N616-G620 WeakPolarHBondContact O-CA 3.46Å; N616-G620 PolarHBondContact O-N 3Å; N616-L636 HydrophobicContact CB-CB 4.33Å; N616-L636 WeakPolarHBondContact CB-O 3.44Å; N616-L636 PolarHBondContact ND2-O 2.96Å; N616-L636 PolarHBondContact O-N 3.32Å; N616-Y644 PolarHBondContact ND2-OH 2.97Å; N616-D753 PolarHBondContact ND2-OD2 3.47Å
617V93.3Very high96.3Very high8 Ų87.4 Ų7.45%0.0484%0.041CC..Hα-helixtrans-73.2-49.4173.9-178.60000111.1T614 S615 Y619 G620 K621 P635 D753T614-V617 HydrophobicContact CG2-CB 4.32Å; T614-V617 HydrophobicContact CG2-CG2 4.14Å; T614-V617 PolarHBondContact O-N 2.79Å; S615-V617 VanDerWaalsContact C-N 3.27Å; S615-V617 PolarHBondContact O-N 2.88Å; V617-Y619 PolarHBondContact O-N 2.94Å; V617-G620 PolarHBondContact O-N 2.9Å; V617-K621 WeakPolarHBondContact O-CG 3.13Å; V617-K621 PolarHBondContact O-N 2.91Å; V617-P635 HydrophobicContact CG2-CB 4.36Å; V617-D753 HydrophobicContact CG2-CB 4.18Å
618V94.1Very high96.3Very high19 Ų197.8 Ų7.812%0.1154%0.043CC..Hα-helixtrans-63-43.9-176.8177.40000112.1E332 L333 T614 S615 A622E332-V618 HydrophobicContact CB-CG2 4.17Å; E332-V618 WeakPolarHBondContact O-CG2 3.39Å; L333-V618 HydrophobicContact CD2-CB 3.99Å; L333-V618 HydrophobicContact CD2-CG1 3.94Å; L333-V618 HydrophobicContact CD2-CG2 3.91Å; L333-V618 HydrophobicContact CG-CG2 4.3Å; T614-V618 PolarHBondContact O-N 2.99Å; S615-V618 PolarHBondContact O-N 2.68Å; V618-A622 PolarHBondContact O-N 2.96Å
619Y97.3Very high96.3Very high0 Ų09.2 Ų9.20%06%0.057CC..Hα-helixtrans-71-39.4174.1-74.4-46.7000112.1K174 T177 R441 N443 A534 S615 V617 K621 A622 T623K174-Y619 HydrophobicContact CB-CD1 4.02Å; K174-Y619 HydrophobicContact CB-CE1 4.14Å; K174-Y619 WeakPolarHBondContact O-CD1 3.21Å; K174-Y619 WeakPolarHBondContact O-CE1 3.33Å; T177-Y619 HydrophobicContact CG2-CD1 3.92Å; T177-Y619 HydrophobicContact CG2-CE1 3.18Å; T177-Y619 PolarHBondContact N-OH 3.19Å; T177-Y619 PolarHBondContact O-OH 2.87Å; R441-Y619 HydrophobicContact CG-CE2 3.92Å; R441-Y619 PolarHBondContact O-OH 3.41Å; N443-Y619 HydrophobicContact CB-CD1 3.65Å; N443-Y619 HydrophobicContact CB-CD2 4.09Å; N443-Y619 HydrophobicContact CB-CE1 3.7Å; N443-Y619 HydrophobicContact CB-CE2 4.14Å; N443-Y619 HydrophobicContact CB-CG 3.85Å; N443-Y619 WeakPolarHBondContact ND2-CD1 3.42Å; A534-Y619 HydrophobicContact CB-CD2 3.58Å; A534-Y619 HydrophobicContact CB-CE2 3.9Å; S615-Y619 WeakPolarHBondContact O-CB 3.46Å; S615-Y619 VanDerWaalsContact O-CD2 3.31Å; S615-Y619 WeakPolarHBondContact O-CD2 3.4Å; S615-Y619 PolarHBondContact O-N 3.47Å; V617-Y619 PolarHBondContact O-N 2.94Å; Y619-K621 VanDerWaalsContact C-N 3.31Å; Y619-K621 PolarHBondContact O-N 3.39Å; Y619-A622 CarbonylContact O-C 3.56Å; Y619-A622 WeakPolarHBondContact O-CA 3.12Å; Y619-A622 PolarHBondContact O-N 2.92Å; Y619-T623 WeakPolarHBondContact O-CB 3.48Å; Y619-T623 PolarHBondContact O-N 3.09Å; Y619-T623 PolarHBondContact O-OG1 3.12Å
620G96.8Very high96.2Very high0 Ų09.8 Ų9.80%06%0.059CC..Hα-helixtrans-53.3-47.2175.700000112.8N616 V617 A622 T623 G633 E634N616-G620 WeakPolarHBondContact O-CA 3.46Å; N616-G620 PolarHBondContact O-N 3Å; V617-G620 PolarHBondContact O-N 2.9Å; G620-A622 PolarHBondContact O-N 3.33Å; G620-T623 PolarHBondContact O-N 2.99Å; G620-T623 VanDerWaalsContact O-O 3.1Å; G620-G633 CarbonylContact O-C 3.59Å; G620-G633 VanDerWaalsContact O-CA 3.31Å; G620-G633 WeakPolarHBondContact O-CA 3.31Å; G620-E634 CarbonylContact C-O 3.48Å; G620-E634 WeakPolarHBondContact CA-O 3.27Å
621K95.7Very high96.2Very high81 Ų8114.1 Ų14.135%0.3528%0.078SC..Hα-helixtrans-56.2-36.5172.5-74.8179.3-179-175.30113.6K459 V617 Y619 E749K459-K621 PolarHBondContact NZ-O 3.22Å; V617-K621 WeakPolarHBondContact O-CG 3.13Å; V617-K621 PolarHBondContact O-N 2.91Å; Y619-K621 VanDerWaalsContact C-N 3.31Å; Y619-K621 PolarHBondContact O-N 3.39Å; K621-E749 VanDerWaalsContact CE-CD 3.42Å; K621-E749 WeakPolarHBondContact CE-OE1 3.5Å; K621-E749 IonicContact NZ-OE1 3.27Å; K621-E749 PolarHBondContact NZ-OE1 3.35Å; K621-E749 IonicContact NZ-OE2 2.92Å; K621-E749 PolarHBondContact NZ-OE2 3.09Å
622A97.1Very high96.2Very high16 Ų1616.8 Ų16.813%0.13210%0.101CC..Hα-helixtrans-88.3-11.5-176.200000113.6K174 K446 K459 V618 Y619 G620K174-A622 HydrophobicContact CB-CB 3.47Å; K174-A622 VanDerWaalsContact CB-CB 3.47Å; K174-A622 HydrophobicContact CG-CB 3.65Å; K446-A622 WeakPolarHBondContact CE-O 3.47Å; K446-A622 PolarHBondContact NZ-O 3.25Å; K459-A622 WeakPolarHBondContact CD-O 3.32Å; V618-A622 PolarHBondContact O-N 2.96Å; Y619-A622 CarbonylContact O-C 3.56Å; Y619-A622 WeakPolarHBondContact O-CA 3.12Å; Y619-A622 PolarHBondContact O-N 2.92Å; G620-A622 PolarHBondContact O-N 3.33Å
623T98.5Very high96.2Very high0 Ų018.3 Ų18.30%012%0.116CC..SBendtrans-102.5133.2-178.6-55.50000110.7N443 A445 K446 L449 E458 Y619 G620 M626 R630 G633N443-T623 PolarHBondContact ND2-OG1 3.47Å; A445-T623 HydrophobicContact CB-CG2 4.35Å; K446-T623 HydrophobicContact CB-CG2 4.4Å; L449-T623 HydrophobicContact CD1-CG2 3.72Å; E458-T623 WeakPolarHBondContact OE1-CA 3.2Å; Y619-T623 WeakPolarHBondContact O-CB 3.48Å; Y619-T623 PolarHBondContact O-N 3.09Å; Y619-T623 PolarHBondContact O-OG1 3.12Å; G620-T623 PolarHBondContact O-N 2.99Å; G620-T623 VanDerWaalsContact O-O 3.1Å; T623-M626 HydrophobicContact CG2-CG 4.41Å; T623-M626 HydrophobicContact CG2-SD 3.9Å; T623-R630 PolarHBondContact O-NH2 3.42Å; T623-G633 PolarHBondContact O-N 3.02Å; T623-G633 VanDerWaalsContact O-N 3.16Å
624G98.3Very high96.4Very high5 Ų522.5 Ų22.55%0.05214%0.136CC..  trans-67.6-175.7174.100000113.8E458 R630E458-G624 PolarHBondContact OE1-N 2.9Å; G624-R630 PolarHBondContact O-NH2 3.04Å
625T98.6Very high96.6Very high9 Ų924 Ų246%0.05515%0.145CC..  trans-60.1139.7177.5-59.70000109.6D563 F564 R630 K631 A632D563-T625 WeakPolarHBondContact OD1-CG2 3.3Å; F564-T625 HydrophobicContact CD2-CG2 4.25Å; F564-T625 VanDerWaalsContact CE2-O 3.24Å; F564-T625 WeakPolarHBondContact CE2-O 3.4Å; T625-R630 CarbonylContact C-O 3.51Å; T625-R630 VanDerWaalsContact CA-O 3.28Å; T625-R630 WeakPolarHBondContact CA-O 3.41Å; T625-R630 WeakPolarHBondContact CG2-O 3.46Å; T625-K631 HydrophobicContact CG2-CD 4Å; T625-A632 PolarHBondContact OG1-N 3.34Å; T625-A632 VanDerWaalsContact OG1-N 3.15Å
626M98.4Very high96.8Very high0 Ų024 Ų240%015%0.145CC..  trans-105.9156.8-177.5-68.9-71.3-66.900111.5A445 L448 L449 T623 D628 G629 R630A445-M626 HydrophobicContact CB-CE 3.69Å; A445-M626 HydrophobicContact CB-SD 4Å; A445-M626 WeakPolarHBondContact O-CE 3.25Å; L448-M626 HydrophobicContact CB-CE 4.41Å; L448-M626 HydrophobicContact CD2-CE 3.99Å; L449-M626 HydrophobicContact CD1-SD 3.9Å; L449-M626 HydrophobicContact CD2-SD 3.73Å; L449-M626 HydrophobicContact CG-SD 3.69Å; T623-M626 HydrophobicContact CG2-CG 4.41Å; T623-M626 HydrophobicContact CG2-SD 3.9Å; M626-D628 WeakPolarHBondContact CB-OD1 3.22Å; M626-D628 PolarHBondContact O-N 3.41Å; M626-D628 VanDerWaalsContact O-N 3.16Å; M626-G629 PolarHBondContact O-N 3.4Å; M626-R630 HydrophobicContact CB-CB 4.26Å; M626-R630 PolarHBondContact N-O 3.15Å
627P98.5Very high96.9Very high0 Ų024 Ų240%015%0.146CC..THydrogen-bonded Turntrans-58.9-19.9176.9-2734.4000115.8L448 I452 S542 A545 I546 V551 F564 I566 G629L448-P627 HydrophobicContact CD2-CG 4.48Å; I452-P627 HydrophobicContact CD1-CG 4.07Å; S542-P627 WeakPolarHBondContact OG-CD 3.44Å; A545-P627 WeakPolarHBondContact CB-O 3.34Å; I546-P627 HydrophobicContact CD1-CB 3.88Å; I546-P627 HydrophobicContact CD1-CG 4.06Å; I546-P627 HydrophobicContact CG1-CB 4.04Å; V551-P627 HydrophobicContact CG1-CB 4.1Å; F564-P627 HydrophobicContact CD1-CG 4.5Å; F564-P627 HydrophobicContact CD2-CG 4.37Å; F564-P627 HydrophobicContact CE1-CG 4.19Å; F564-P627 HydrophobicContact CE2-CG 4.06Å; F564-P627 HydrophobicContact CZ-CG 3.96Å; I566-P627 WeakPolarHBondContact CD1-O 3.23Å; P627-G629 PolarHBondContact O-N 3.04Å
628D98.3Very high97Very high12 Ų1223.8 Ų23.86%0.06414%0.144CC..THydrogen-bonded Turntrans-76.2-6.1173.671.1-15.9000114.1H538 D541 S542 F570 M626 R630H538-D628 IonicContact CE1-OD2 2.83Å; H538-D628 IonicContact CG-OD2 2.79Å; H538-D628 IonicContact ND1-OD2 3.63Å; H538-D628 PolarHBondContact ND1-OD2 2.83Å; D541-D628 HydrophobicContact CB-CB 3.69Å; S542-D628 PolarHBondContact OG-N 3.41Å; F570-D628 HydrophobicContact CZ-CB 4.48Å; M626-D628 WeakPolarHBondContact CB-OD1 3.22Å; M626-D628 PolarHBondContact O-N 3.41Å; M626-D628 VanDerWaalsContact O-N 3.16Å; D628-R630 WeakPolarHBondContact OD1-CB 3.38Å; D628-R630 PolarHBondContact OD1-N 3.39Å
629G97.5Very high97.1Very high30 Ų3022.9 Ų22.931%0.30914%0.139SC..SBendtrans96.9-5.6-179.500000114.8M626 P627 K631M626-G629 PolarHBondContact O-N 3.4Å; P627-G629 PolarHBondContact O-N 3.04Å; G629-K631 PolarHBondContact O-N 2.99Å
630R97.8Very high97.1Very high14 Ų1422.9 Ų22.95%0.05314%0.139CC..PPolyproline II helixtrans-59.2128.2174-173.5-154.676.985.7-6.8110H538 T623 G624 T625 M626 D628 E634H538-R630 VanDerWaalsContact CE1-CD 3.41Å; H538-R630 WeakPolarHBondContact CE1-CD 3.37Å; T623-R630 PolarHBondContact O-NH2 3.42Å; G624-R630 PolarHBondContact O-NH2 3.04Å; T625-R630 CarbonylContact C-O 3.51Å; T625-R630 VanDerWaalsContact CA-O 3.28Å; T625-R630 WeakPolarHBondContact CA-O 3.41Å; T625-R630 WeakPolarHBondContact CG2-O 3.46Å; M626-R630 HydrophobicContact CB-CB 4.26Å; M626-R630 PolarHBondContact N-O 3.15Å; D628-R630 WeakPolarHBondContact OD1-CB 3.38Å; D628-R630 PolarHBondContact OD1-N 3.39Å; R630-E634 HydrophobicContact CG-CB 4.3Å; R630-E634 VanDerWaalsContact NH1-C 3.34Å; R630-E634 PolarHBondContact NH1-O 2.91Å
631K97.7Very high97.1Very high91 Ų9123.3 Ų23.340%0.39614%0.141SC..PPolyproline II helixtrans-84152.9-173.9-62.7-53.7-170.1-179.20112.8D563 T625 G629 G633 E634D563-K631 IonicContact OD1-NZ 3.19Å; D563-K631 PolarHBondContact OD1-NZ 3.35Å; D563-K631 IonicContact OD2-NZ 3.82Å; T625-K631 HydrophobicContact CG2-CD 4Å; G629-K631 PolarHBondContact O-N 2.99Å; K631-G633 PolarHBondContact O-N 3.34Å; K631-E634 HydrophobicContact CB-CG 4.22Å; K631-E634 PolarHBondContact N-OE2 3.45Å; K631-E634 WeakPolarHBondContact O-CB 3.24Å; K631-E634 PolarHBondContact O-N 3.4Å
632A97.7Very high97.2Very high59 Ų5919.7 Ų19.749%0.48813%0.126SC..THydrogen-bonded Turntrans-52.1128.8179.300000111.8T625 E634T625-A632 PolarHBondContact OG1-N 3.34Å; T625-A632 VanDerWaalsContact OG1-N 3.15Å; A632-E634 VanDerWaalsContact C-N 3.32Å; A632-E634 PolarHBondContact O-N 3.46Å
633G95.7Very high97.2Very high31 Ų3119.1 Ų19.132%0.3212%0.121SC..THydrogen-bonded Turntrans86.1-13.4177.300000116.2G620 T623 K631G620-G633 CarbonylContact O-C 3.59Å; G620-G633 VanDerWaalsContact O-CA 3.31Å; G620-G633 WeakPolarHBondContact O-CA 3.31Å; T623-G633 PolarHBondContact O-N 3.02Å; T623-G633 VanDerWaalsContact O-N 3.16Å; K631-G633 PolarHBondContact O-N 3.34Å
634E95.7Very high97Very high93 Ų9321.7 Ų21.744%0.43513%0.131SC..PPolyproline II helixtrans-62.6155173.1-67.3178.6160.500110.6G620 R630 K631 A632G620-E634 CarbonylContact C-O 3.48Å; G620-E634 WeakPolarHBondContact CA-O 3.27Å; R630-E634 HydrophobicContact CG-CB 4.3Å; R630-E634 VanDerWaalsContact NH1-C 3.34Å; R630-E634 PolarHBondContact NH1-O 2.91Å; K631-E634 HydrophobicContact CB-CG 4.22Å; K631-E634 PolarHBondContact N-OE2 3.45Å; K631-E634 WeakPolarHBondContact O-CB 3.24Å; K631-E634 PolarHBondContact O-N 3.4Å; A632-E634 VanDerWaalsContact C-N 3.32Å; A632-E634 PolarHBondContact O-N 3.46Å
635P95.2Very high96.7Very high36 Ų3623.6 Ų23.623%0.23415%0.151CC..PPolyproline II helixtrans-58.1147.9172.4-25.836.1000112.5V617 Y644 D753V617-P635 HydrophobicContact CG2-CB 4.36Å; P635-Y644 HydrophobicContact CB-CE2 4.26Å; P635-D753 HydrophobicContact CG-CB 4.48Å
636L96.8Very high96.5Very high0 Ų023.2 Ų23.20%015%0.148CC..PPolyproline II helixtrans-78.9160.4159.8-60.1172.4000109.2A445 H538 N616 Y644A445-L636 HydrophobicContact CB-CD1 4.27Å; A445-L636 HydrophobicContact CB-CD2 3.93Å; H538-L636 HydrophobicContact CB-CD2 4.36Å; H538-L636 WeakPolarHBondContact NE2-CA 3.35Å; N616-L636 HydrophobicContact CB-CB 4.33Å; N616-L636 WeakPolarHBondContact CB-O 3.44Å; N616-L636 PolarHBondContact ND2-O 2.96Å; N616-L636 PolarHBondContact O-N 3.32Å; L636-Y644 WeakPolarHBondContact O-CE2 3.32Å; L636-Y644 PolarHBondContact O-OH 2.91Å; L636-Y644 VanDerWaalsContact O-OH 3.11Å
637A95.6Very high96.4Very high1 Ų124.3 Ų24.31%0.00815%0.153CC..PPolyproline II helixtrans-64.1145.817400000112.3S537 H538 N641 P642 Y644S537-A637 VanDerWaalsContact OG-CB 3.22Å; S537-A637 WeakPolarHBondContact OG-CB 3.49Å; H538-A637 PolarHBondContact CD2-N 2.96Å; H538-A637 PolarHBondContact NE2-N 2.84Å; H538-A637 VanDerWaalsContact NE2-N 3.19Å; A637-N641 HydrophobicContact CB-CB 4.39Å; A637-P642 WeakPolarHBondContact CB-O 3.44Å; A637-Y644 HydrophobicContact CB-CE2 4.34Å
638P95Very high96.1Very high3 Ų331 Ų312%0.01919%0.185CC..SBendtrans-75.1134.517730.9-34.8000111.7T612 A640 N641T612-P638 VanDerWaalsContact OG1-CA 3.24Å; T612-P638 WeakPolarHBondContact OG1-CA 3.4Å; P638-A640 PolarHBondContact O-N 3.23Å; P638-N641 HydrophobicContact CG-CB 4.08Å; P638-N641 WeakPolarHBondContact O-CB 3.26Å; P638-N641 VanDerWaalsContact O-CG 3.31Å; P638-N641 PolarHBondContact O-N 3.25Å; P638-N641 PolarHBondContact O-OD1 3.39Å; P638-N641 VanDerWaalsContact O-OD1 3.06Å
639G96.3Very high96Very high0 Ų034.9 Ų34.90%021%0.205CC..THydrogen-bonded Turntrans52.6-131.4177.800000113I610 T612 N641I610-G639 WeakPolarHBondContact CG2-O 3.49Å; I610-G639 WeakPolarHBondContact O-CA 3.42Å; T612-G639 PolarHBondContact OG1-N 3.36Å; G639-N641 VanDerWaalsContact C-N 3.33Å
640A98Very high95.9Very high0 Ų033.6 Ų33.60%019%0.193CC..THydrogen-bonded Turntrans-92.616.4175.500000112.9Y573 I610 P638 L658 L661 I670 S671Y573-A640 WeakPolarHBondContact CE1-O 3.43Å; I610-A640 HydrophobicContact CB-CB 3.96Å; I610-A640 HydrophobicContact CD1-CB 4.38Å; I610-A640 HydrophobicContact CG2-CB 3.62Å; P638-A640 PolarHBondContact O-N 3.23Å; A640-L658 HydrophobicContact CB-CD2 4.44Å; A640-L661 HydrophobicContact CB-CD1 4.13Å; A640-I670 HydrophobicContact CB-CG2 3.51Å; A640-S671 WeakPolarHBondContact CA-O 3.42Å; A640-S671 VanDerWaalsContact CB-O 3.3Å; A640-S671 WeakPolarHBondContact CB-O 3.32Å; A640-S671 PolarHBondContact N-O 3.49Å
641N97.8Very high95.9Very high9 Ų933.3 Ų33.35%0.04819%0.192CC..PPolyproline II helixtrans-62.3147.8176.1-78.452.6000111.5S537 A637 P638 G639 T673S537-N641 WeakPolarHBondContact CB-O 3.5Å; S537-N641 PolarHBondContact OG-O 2.96Å; A637-N641 HydrophobicContact CB-CB 4.39Å; P638-N641 HydrophobicContact CG-CB 4.08Å; P638-N641 WeakPolarHBondContact O-CB 3.26Å; P638-N641 VanDerWaalsContact O-CG 3.31Å; P638-N641 PolarHBondContact O-N 3.25Å; P638-N641 PolarHBondContact O-OD1 3.39Å; P638-N641 VanDerWaalsContact O-OD1 3.06Å; G639-N641 VanDerWaalsContact C-N 3.33Å; N641-T673 PolarHBondContact ND2-O 2.95Å; N641-T673 PolarHBondContact OD1-N 3.34Å
642P97.9Very high95.9Very high5 Ų532.8 Ų32.83%0.03219%0.193CC..PPolyproline II helixtrans-50.8153161.2-3041000112.8Y573 A637 A646 E647 L658Y573-P642 HydrophobicContact CD1-CB 4.49Å; Y573-P642 HydrophobicContact CD1-CG 4.34Å; Y573-P642 HydrophobicContact CE1-CG 4.41Å; Y573-P642 WeakPolarHBondContact O-CB 3.48Å; A637-P642 WeakPolarHBondContact CB-O 3.44Å; P642-A646 HydrophobicContact CB-CB 4.12Å; P642-E647 HydrophobicContact CB-CG 3.54Å; P642-E647 HydrophobicContact CG-CG 3.61Å; P642-L658 HydrophobicContact CG-CD1 4.34Å
643S96.5Very high95.9Very high4 Ų430.6 Ų30.63%0.02818%0.175CC..PPolyproline II helixtrans-65155.1176.770.10000110.9S537 H538 D541 G645 A646S537-S643 PolarHBondContact OG-N 2.92Å; H538-S643 VanDerWaalsContact CE1-CB 3.49Å; H538-S643 WeakPolarHBondContact CE1-CB 3.42Å; D541-S643 WeakPolarHBondContact OD2-CB 3.18Å; D541-S643 PolarHBondContact OD2-OG 2.9Å; S643-G645 PolarHBondContact O-N 2.85Å; S643-G645 VanDerWaalsContact O-N 3.16Å; S643-A646 WeakPolarHBondContact O-CB 3.48Å; S643-A646 PolarHBondContact O-N 3.35Å; S643-A646 WeakPolarHBondContact OG-CB 3.48Å
644Y93.4Very high96Very high54 Ų5429.1 Ų29.121%0.21216%0.16CC..THydrogen-bonded Turntrans-56.8123.5-176.2-62.8-100.6000111.1N616 P635 L636 A637 A646 D753 S756 R757N616-Y644 PolarHBondContact ND2-OH 2.97Å; P635-Y644 HydrophobicContact CB-CE2 4.26Å; L636-Y644 WeakPolarHBondContact O-CE2 3.32Å; L636-Y644 PolarHBondContact O-OH 2.91Å; L636-Y644 VanDerWaalsContact O-OH 3.11Å; A637-Y644 HydrophobicContact CB-CE2 4.34Å; Y644-A646 VanDerWaalsContact C-N 3.26Å; Y644-A646 PolarHBondContact O-N 2.95Å; Y644-D753 WeakPolarHBondContact CE1-OD1 3.43Å; Y644-D753 VanDerWaalsContact CZ-OD1 3.27Å; Y644-D753 PolarHBondContact OH-OD1 2.78Å; Y644-S756 WeakPolarHBondContact CD1-OG 3.46Å; Y644-S756 WeakPolarHBondContact CE1-OG 3.36Å; Y644-R757 HydrophobicContact CD1-CG 4.37Å; Y644-R757 HydrophobicContact CE1-CG 3.7Å
645G91.7Very high96.1Very high45 Ų4524.9 Ų24.946%0.46414%0.14SC..THydrogen-bonded Turntrans74.28.4-177.400000115.3S643S643-G645 PolarHBondContact O-N 2.85Å; S643-G645 VanDerWaalsContact O-N 3.16Å
646A95.7Very high96.2Very high1 Ų125 Ų251%0.00814%0.139CC..THydrogen-bonded Turntrans-70-41.3173.200000112.5K572 N575 P642 S643 Y644 Q648K572-A646 HydrophobicContact CB-CB 3.87Å; K572-A646 HydrophobicContact CD-CB 3.89Å; N575-A646 PolarHBondContact ND2-O 3.49Å; N575-A646 PolarHBondContact OD1-O 2.97Å; P642-A646 HydrophobicContact CB-CB 4.12Å; S643-A646 WeakPolarHBondContact O-CB 3.48Å; S643-A646 PolarHBondContact O-N 3.35Å; S643-A646 WeakPolarHBondContact OG-CB 3.48Å; Y644-A646 VanDerWaalsContact C-N 3.26Å; Y644-A646 PolarHBondContact O-N 2.95Å; A646-Q648 PolarHBondContact O-N 3.22Å
647E95.5Very high96.3Very high22 Ų2225 Ų2510%0.10314%0.139CC..  trans-70.7109.1-175.4-66.3161.5102.200110.9P642 S654 Q674 T758 H760P642-E647 HydrophobicContact CB-CG 3.54Å; P642-E647 HydrophobicContact CG-CG 3.61Å; E647-S654 WeakPolarHBondContact OE1-CB 3.49Å; E647-S654 PolarHBondContact OE1-OG 2.9Å; E647-Q674 PolarHBondContact OE1-NE2 3.42Å; E647-Q674 PolarHBondContact OE1-OE1 2.91Å; E647-T758 HydrophobicContact CB-CG2 3.94Å; E647-T758 WeakPolarHBondContact OE2-CB 3.27Å; E647-T758 PolarHBondContact OE2-OG1 3.39Å; E647-H760 IonicContact OE1-CE1 2.95Å; E647-H760 PolarHBondContact OE1-CE1 3.15Å; E647-H760 IonicContact OE1-NE2 3.05Å; E647-H760 PolarHBondContact OE1-NE2 3.39Å; E647-H760 VanDerWaalsContact OE1-NE2 3.15Å
648Q93Very high96.4Very high141 Ų14125.2 Ų25.266%0.65914%0.14SC*.  trans-121.3-12.5-179.4-63.2-170.51.300113.4N575 A646N575-Q648 PolarHBondContact OD1-N 2.92Å; A646-Q648 PolarHBondContact O-N 3.22Å
649N95.6Very high96.6Very high93 Ų9325.8 Ų25.850%0.49714%0.143SC..SBendtrans-101.20.3-172.1-70.2-22.7000115.1N575 A653N575-N649 PolarHBondContact O-ND2 3.2Å; N575-N649 PolarHBondContact OD1-N 2.94Å; N649-A653 HydrophobicContact CB-CB 3.46Å; N649-A653 VanDerWaalsContact CB-CB 3.46Å
650G95.9Very high96.7Very high4 Ų430.1 Ų30.14%0.04116%0.162CC..  trans105.5174.4179.800000113.2A653 S654G650-A653 PolarHBondContact O-N 2.83Å; G650-S654 PolarHBondContact O-N 2.96Å
651L97Very high96.7Very high8 Ų830.3 Ų30.34%0.04216%0.163CC..Hα-helixtrans-60.5-47.5-177.6174.962.1000111.4A653 S654 L655 Q674 I676 V695 H760 K762 M763L651-A653 VanDerWaalsContact C-N 3.33Å; L651-A653 PolarHBondContact O-N 3.13Å; L651-S654 WeakPolarHBondContact O-CB 3.3Å; L651-S654 PolarHBondContact O-N 3.37Å; L651-L655 HydrophobicContact CD1-CD1 3.93Å; L651-L655 HydrophobicContact CD1-CD2 4.37Å; L651-L655 HydrophobicContact CD1-CG 3.9Å; L651-L655 HydrophobicContact CD2-CD1 4.4Å; L651-L655 HydrophobicContact CG-CD1 3.83Å; L651-L655 HydrophobicContact CG-CG 4.2Å; L651-L655 WeakPolarHBondContact O-CB 3.38Å; L651-L655 VanDerWaalsContact O-CG 3.32Å; L651-L655 WeakPolarHBondContact O-CG 3.34Å; L651-L655 PolarHBondContact O-N 2.85Å; L651-Q674 HydrophobicContact CD1-CB 3.82Å; L651-Q674 HydrophobicContact CD1-CG 3.91Å; L651-I676 HydrophobicContact CD2-CD1 3.68Å; L651-V695 HydrophobicContact CD2-CG1 4.23Å; L651-H760 HydrophobicContact CB-CB 4.13Å; L651-H760 PolarHBondContact N-ND1 2.93Å; L651-K762 PolarHBondContact N-O 3.48Å; L651-M763 PolarHBondContact N-OXT 2.83Å
652L97.3Very high96.6Very high79 Ų7930.7 Ų30.741%0.41417%0.166SC..Hα-helixtrans-62.8-39.1-176.8-66.1-180000111.9L655 N656 V695 M763L652-L655 PolarHBondContact O-N 3.41Å; L652-N656 VanDerWaalsContact O-CB 3.31Å; L652-N656 WeakPolarHBondContact O-CB 3.41Å; L652-N656 PolarHBondContact O-N 2.87Å; L652-N656 PolarHBondContact O-OD1 2.85Å; L652-V695 HydrophobicContact CD2-CG2 4.08Å; L652-M763 WeakPolarHBondContact CB-OXT 3.33Å; L652-M763 HydrophobicContact CD1-CB 4.35Å; L652-M763 HydrophobicContact CG-CB 4.37Å; L652-M763 WeakPolarHBondContact CG-OXT 3.46Å; L652-M763 PolarHBondContact N-OXT 3.07Å
653A97.7Very high96.6Very high14 Ų1431 Ų3112%0.11617%0.167CC..Hα-helixtrans-65.9-40.2176.200000111.8D576 N649 G650 L651 N656 S657D576-A653 HydrophobicContact CB-CB 4.31Å; D576-A653 PolarHBondContact N-O 2.69Å; N649-A653 HydrophobicContact CB-CB 3.46Å; N649-A653 VanDerWaalsContact CB-CB 3.46Å; G650-A653 PolarHBondContact O-N 2.83Å; L651-A653 VanDerWaalsContact C-N 3.33Å; L651-A653 PolarHBondContact O-N 3.13Å; A653-N656 PolarHBondContact O-N 2.95Å; A653-S657 PolarHBondContact O-N 3Å; A653-S657 VanDerWaalsContact O-N 3.15Å
654S98Very high96.5Very high0 Ų036.7 Ų36.70%019%0.193CC..Hα-helixtrans-62.6-48.8174.2-179.80000111.7G574 E647 G650 L651 N656 S657 L658 Q674G574-S654 VanDerWaalsContact O-CA 3.31Å; G574-S654 WeakPolarHBondContact O-CA 3.48Å; E647-S654 WeakPolarHBondContact OE1-CB 3.49Å; E647-S654 PolarHBondContact OE1-OG 2.9Å; G650-S654 PolarHBondContact O-N 2.96Å; L651-S654 WeakPolarHBondContact O-CB 3.3Å; L651-S654 PolarHBondContact O-N 3.37Å; S654-N656 PolarHBondContact O-N 3.16Å; S654-S657 PolarHBondContact O-N 2.74Å; S654-L658 VanDerWaalsContact O-CD1 3.24Å; S654-L658 WeakPolarHBondContact O-CD1 3.49Å; S654-L658 PolarHBondContact O-N 2.5Å; S654-Q674 PolarHBondContact OG-NE2 3.31Å
655L98.4Very high96.7Very high3 Ų337.5 Ų37.52%0.01620%0.196CC..Hα-helixtrans-59.3-45.6176.2-69.2-179.6000111.6L651 L652 S657 L658 T659 N672 Q674 V695 Y699 L707L651-L655 HydrophobicContact CD1-CD1 3.93Å; L651-L655 HydrophobicContact CD1-CD2 4.37Å; L651-L655 HydrophobicContact CD1-CG 3.9Å; L651-L655 HydrophobicContact CD2-CD1 4.4Å; L651-L655 HydrophobicContact CG-CD1 3.83Å; L651-L655 HydrophobicContact CG-CG 4.2Å; L651-L655 WeakPolarHBondContact O-CB 3.38Å; L651-L655 VanDerWaalsContact O-CG 3.32Å; L651-L655 WeakPolarHBondContact O-CG 3.34Å; L651-L655 PolarHBondContact O-N 2.85Å; L652-L655 PolarHBondContact O-N 3.41Å; L655-S657 VanDerWaalsContact C-N 3.31Å; L655-S657 PolarHBondContact O-N 3.25Å; L655-L658 WeakPolarHBondContact O-CA 3.39Å; L655-L658 WeakPolarHBondContact O-CB 3.46Å; L655-L658 PolarHBondContact O-N 2.67Å; L655-T659 WeakPolarHBondContact O-CG2 3.42Å; L655-T659 PolarHBondContact O-N 3.36Å; L655-N672 WeakPolarHBondContact CD2-ND2 3.17Å; L655-Q674 HydrophobicContact CD2-CG 3.9Å; L655-V695 HydrophobicContact CD1-CG1 3.47Å; L655-V695 VanDerWaalsContact CD1-CG1 3.47Å; L655-Y699 HydrophobicContact CB-CD2 3.68Å; L655-Y699 HydrophobicContact CB-CE2 3.99Å; L655-Y699 HydrophobicContact CB-CG 4.49Å; L655-Y699 HydrophobicContact CD2-CD2 3.86Å; L655-Y699 HydrophobicContact CD2-CE1 4.43Å; L655-Y699 HydrophobicContact CD2-CE2 3.76Å; L655-Y699 HydrophobicContact CD2-CG 4.22Å; L655-Y699 HydrophobicContact CG-CD2 4.21Å; L655-Y699 HydrophobicContact CG-CE2 4.45Å; L655-Y699 WeakPolarHBondContact O-CE2 3.29Å; L655-L707 HydrophobicContact CD2-CD1 3.81Å; L655-L707 HydrophobicContact CD2-CD2 4.44Å
656N98.3Very high97Very high40 Ų4035.3 Ų35.321%0.21417%0.174CC..Hα-helixtrans-60.4-35.3178.3-76.4-10.2000113.4D576 L652 A653 S654 L658 T659 K660 Q702D576-N656 HydrophobicContact CB-CB 4.08Å; D576-N656 PolarHBondContact OD2-ND2 3.49Å; D576-N656 VanDerWaalsContact OD2-ND2 3.08Å; L652-N656 VanDerWaalsContact O-CB 3.31Å; L652-N656 WeakPolarHBondContact O-CB 3.41Å; L652-N656 PolarHBondContact O-N 2.87Å; L652-N656 PolarHBondContact O-OD1 2.85Å; A653-N656 PolarHBondContact O-N 2.95Å; S654-N656 PolarHBondContact O-N 3.16Å; N656-L658 VanDerWaalsContact C-N 3.28Å; N656-L658 PolarHBondContact O-N 3.45Å; N656-T659 PolarHBondContact O-N 3.47Å; N656-T659 PolarHBondContact O-OG1 3.46Å; N656-K660 WeakPolarHBondContact O-CE 3.41Å; N656-Q702 PolarHBondContact OD1-NE2 3.17Å
657S98.5Very high97.1Very high0 Ų036.9 Ų36.90%018%0.182CC..Hα-helixtrans-64-35.9172.8-78.50000112.1G574 N575 D576 D581 A653 S654 L655 K660G574-S657 WeakPolarHBondContact CA-OG 3.44Å; G574-S657 PolarHBondContact N-OG 3.16Å; N575-S657 PolarHBondContact N-OG 2.91Å; N575-S657 VanDerWaalsContact N-OG 3.12Å; D576-S657 WeakPolarHBondContact CA-OG 2.7Å; D576-S657 PolarHBondContact N-OG 3.19Å; D581-S657 VanDerWaalsContact CG-OG 3.23Å; D581-S657 WeakPolarHBondContact OD1-CB 3.45Å; D581-S657 PolarHBondContact OD1-OG 2.62Å; D581-S657 WeakPolarHBondContact OD2-CA 3.29Å; D581-S657 WeakPolarHBondContact OD2-CB 3.26Å; D581-S657 PolarHBondContact OD2-OG 3.3Å; A653-S657 PolarHBondContact O-N 3Å; A653-S657 VanDerWaalsContact O-N 3.15Å; S654-S657 PolarHBondContact O-N 2.74Å; L655-S657 VanDerWaalsContact C-N 3.31Å; L655-S657 PolarHBondContact O-N 3.25Å; S657-K660 WeakPolarHBondContact O-CB 3.2Å; S657-K660 WeakPolarHBondContact O-CG 3.31Å; S657-K660 PolarHBondContact O-N 2.7Å
658L97.8Very high97.2Very high4 Ų436 Ų362%0.02118%0.178CC..Hα-helixtrans-75.9-26.9178.4-8779.7000113.4Y573 A640 P642 S654 L655 N656 K660 L661 N672 Y699Y573-L658 HydrophobicContact CE1-CD1 4.05Å; Y573-L658 VanDerWaalsContact OH-CD1 3.31Å; Y573-L658 WeakPolarHBondContact OH-CD1 3.31Å; Y573-L658 WeakPolarHBondContact OH-CG 3.36Å; A640-L658 HydrophobicContact CB-CD2 4.44Å; P642-L658 HydrophobicContact CG-CD1 4.34Å; S654-L658 VanDerWaalsContact O-CD1 3.24Å; S654-L658 WeakPolarHBondContact O-CD1 3.49Å; S654-L658 PolarHBondContact O-N 2.5Å; L655-L658 WeakPolarHBondContact O-CA 3.39Å; L655-L658 WeakPolarHBondContact O-CB 3.46Å; L655-L658 PolarHBondContact O-N 2.67Å; N656-L658 VanDerWaalsContact C-N 3.28Å; N656-L658 PolarHBondContact O-N 3.45Å; L658-K660 PolarHBondContact O-N 3.1Å; L658-K660 VanDerWaalsContact O-N 3.15Å; L658-L661 PolarHBondContact O-N 2.89Å; L658-L661 VanDerWaalsContact O-N 3.14Å; L658-N672 HydrophobicContact CD2-CB 3.34Å; L658-N672 WeakPolarHBondContact CD2-ND2 3.33Å; L658-N672 WeakPolarHBondContact CD2-OD1 3.48Å; L658-Y699 HydrophobicContact CB-CE2 4.06Å
659T98Very high97.5Very high16 Ų1629.3 Ų29.310%0.09815%0.147CC..THydrogen-bonded Turntrans-64.3-15.9173.869.60000112.3L655 N656 L661 Y699 Q702 A704L655-T659 WeakPolarHBondContact O-CG2 3.42Å; L655-T659 PolarHBondContact O-N 3.36Å; N656-T659 PolarHBondContact O-N 3.47Å; N656-T659 PolarHBondContact O-OG1 3.46Å; T659-L661 VanDerWaalsContact C-N 3.32Å; T659-Y699 HydrophobicContact CG2-CD2 3.66Å; T659-Y699 HydrophobicContact CG2-CE2 3.94Å; T659-Q702 HydrophobicContact CG2-CB 3.61Å; T659-Q702 HydrophobicContact CG2-CG 4.45Å; T659-A704 HydrophobicContact CG2-CB 4.04Å
660K98.2Very high97.6Very high91 Ų9125.1 Ų25.140%0.39612%0.124SC..THydrogen-bonded Turntrans-74.9-20.1176-49.4-50.7177.9-162.90113.4D581 V585 N656 S657 L658 P662D581-K660 HydrophobicContact CB-CB 4.38Å; D581-K660 HydrophobicContact CB-CG 4.05Å; V585-K660 HydrophobicContact CG2-CB 4.39Å; V585-K660 VanDerWaalsContact CG2-O 3.29Å; V585-K660 WeakPolarHBondContact CG2-O 3.18Å; N656-K660 WeakPolarHBondContact O-CE 3.41Å; S657-K660 WeakPolarHBondContact O-CB 3.2Å; S657-K660 WeakPolarHBondContact O-CG 3.31Å; S657-K660 PolarHBondContact O-N 2.7Å; L658-K660 PolarHBondContact O-N 3.1Å; L658-K660 VanDerWaalsContact O-N 3.15Å; K660-P662 VanDerWaalsContact O-CD 3.31Å; K660-P662 WeakPolarHBondContact O-CD 3.37Å
661L98.4Very high97.8Very high4 Ų425 Ų252%0.02112%0.122CC..SBendtrans-76.4118-176.6-64.8178.9000110.7F536 Y573 A584 I610 A640 L658 T659 Y663 I670F536-L661 HydrophobicContact CE1-CD1 4.06Å; F536-L661 HydrophobicContact CE1-CD2 3.96Å; F536-L661 HydrophobicContact CZ-CD1 4.4Å; F536-L661 HydrophobicContact CZ-CD2 3.67Å; Y573-L661 VanDerWaalsContact OH-CD1 3.23Å; Y573-L661 WeakPolarHBondContact OH-CD1 3.47Å; A584-L661 HydrophobicContact CB-CD2 3.88Å; I610-L661 HydrophobicContact CD1-CD1 3.93Å; A640-L661 HydrophobicContact CB-CD1 4.13Å; L658-L661 PolarHBondContact O-N 2.89Å; L658-L661 VanDerWaalsContact O-N 3.14Å; T659-L661 VanDerWaalsContact C-N 3.32Å; L661-Y663 PolarHBondContact O-N 3.4Å; L661-I670 HydrophobicContact CB-CD1 3.87Å; L661-I670 HydrophobicContact CD1-CG2 3.88Å
662P96.1Very high97.8Very high17 Ų1724.6 Ų24.611%0.1112%0.12CC..  trans-76.5112-17629.8-35.2000111.6V585 L588 K660 E664 Y665V585-P662 HydrophobicContact CG1-CG 4.33Å; L588-P662 HydrophobicContact CD2-CG 4.29Å; K660-P662 VanDerWaalsContact O-CD 3.31Å; K660-P662 WeakPolarHBondContact O-CD 3.37Å; P662-E664 WeakPolarHBondContact CA-OE2 3.44Å; P662-E664 VanDerWaalsContact CB-CD 3.41Å; P662-E664 HydrophobicContact CB-CG 4.43Å; P662-E664 VanDerWaalsContact CB-OE1 3.27Å; P662-E664 WeakPolarHBondContact CB-OE1 3.47Å; P662-E664 VanDerWaalsContact CB-OE2 3.32Å; P662-E664 WeakPolarHBondContact CB-OE2 3.26Å; P662-E664 PolarHBondContact O-N 3.19Å; P662-Y665 HydrophobicContact CB-CD2 3.84Å; P662-Y665 HydrophobicContact CB-CE2 4.44Å; P662-Y665 HydrophobicContact CG-CD2 3.65Å; P662-Y665 HydrophobicContact CG-CE2 4.36Å; P662-Y665 HydrophobicContact CG-CG 4.41Å; P662-Y665 PolarHBondContact O-N 3.11Å; P662-Y665 VanDerWaalsContact O-N 3.12Å
663Y97.1Very high97.8Very high10 Ų1021.1 Ų21.14%0.03910%0.102CC..G310 helixtrans-57.7-29.7179.2173.8-122.4000112.9V411 M412 W416 L661 Y665 A666 L667 H705V411-Y663 HydrophobicContact CB-CD1 4.31Å; V411-Y663 HydrophobicContact CG2-CD1 3.92Å; V411-Y663 HydrophobicContact CG2-CE1 4.44Å; V411-Y663 HydrophobicContact CG2-CG 4.46Å; M412-Y663 HydrophobicContact CG-CE1 3.85Å; W416-Y663 AromaticContact NE1-CZ 3.99Å; W416-Y663 PolarHBondContact NE1-OH 3.5Å; L661-Y663 PolarHBondContact O-N 3.4Å; Y663-Y665 PolarHBondContact O-N 3.26Å; Y663-Y665 VanDerWaalsContact O-N 3.13Å; Y663-A666 WeakPolarHBondContact CD2-O 3.21Å; Y663-A666 WeakPolarHBondContact CE2-O 3.46Å; Y663-A666 CarbonylContact O-C 3.59Å; Y663-A666 WeakPolarHBondContact O-CA 3.44Å; Y663-A666 PolarHBondContact O-N 2.9Å; Y663-L667 HydrophobicContact CD1-CD2 4.31Å; Y663-L667 HydrophobicContact CE1-CD2 3.87Å; Y663-L667 HydrophobicContact CE2-CD2 4.42Å; Y663-L667 PolarHBondContact O-N 2.95Å; Y663-L667 PolarHBondContact OH-O 2.89Å; Y663-H705 HydrophobicContact CD2-CB 4.19Å; Y663-H705 AromaticContact CD2-CD2 3.18Å; Y663-H705 WeakPolarHBondContact CD2-CD2 3.42Å; Y663-H705 AromaticContact CD2-CG 3.77Å; Y663-H705 AromaticContact CD2-NE2 3.84Å; Y663-H705 AromaticContact CE2-CD2 3.07Å; Y663-H705 WeakPolarHBondContact CE2-CD2 3Å; Y663-H705 AromaticContact CE2-CG 3.97Å; Y663-H705 AromaticContact CE2-NE2 3.23Å; Y663-H705 WeakPolarHBondContact CE2-NE2 3.22Å; Y663-H705 AromaticContact CG-CD2 3.77Å; Y663-H705 AromaticContact CZ-CD2 3.58Å; Y663-H705 AromaticContact CZ-NE2 3.6Å
664E95.6Very high97.8Very high125 Ų12520.9 Ų20.958%0.58410%0.099SC*.G310 helixtrans-62.9-19.517969.5-85-164.700114P662P662-E664 WeakPolarHBondContact CA-OE2 3.44Å; P662-E664 VanDerWaalsContact CB-CD 3.41Å; P662-E664 HydrophobicContact CB-CG 4.43Å; P662-E664 VanDerWaalsContact CB-OE1 3.27Å; P662-E664 WeakPolarHBondContact CB-OE1 3.47Å; P662-E664 VanDerWaalsContact CB-OE2 3.32Å; P662-E664 WeakPolarHBondContact CB-OE2 3.26Å; P662-E664 PolarHBondContact O-N 3.19Å
665Y97.4Very high97.7Very high70 Ų7021.2 Ų21.228%0.27510%0.101SC..G310 helixtrans-96.1-1.1172-68.1-93.4000113K589 T608 P662 Y663K589-Y665 HydrophobicContact CB-CD1 4.21Å; K589-Y665 HydrophobicContact CB-CE1 4.32Å; K589-Y665 HydrophobicContact CD-CD2 4.38Å; K589-Y665 HydrophobicContact CD-CE1 4.14Å; K589-Y665 HydrophobicContact CD-CE2 4.07Å; K589-Y665 VanDerWaalsContact CE-CE2 3.4Å; K589-Y665 HydrophobicContact CG-CD1 3.77Å; K589-Y665 HydrophobicContact CG-CD2 4Å; K589-Y665 HydrophobicContact CG-CE1 3.87Å; K589-Y665 HydrophobicContact CG-CE2 4.15Å; K589-Y665 HydrophobicContact CG-CG 3.82Å; T608-Y665 WeakPolarHBondContact CG2-O 3.27Å; P662-Y665 HydrophobicContact CB-CD2 3.84Å; P662-Y665 HydrophobicContact CB-CE2 4.44Å; P662-Y665 HydrophobicContact CG-CD2 3.65Å; P662-Y665 HydrophobicContact CG-CE2 4.36Å; P662-Y665 HydrophobicContact CG-CG 4.41Å; P662-Y665 PolarHBondContact O-N 3.11Å; P662-Y665 VanDerWaalsContact O-N 3.12Å; Y663-Y665 PolarHBondContact O-N 3.26Å; Y663-Y665 VanDerWaalsContact O-N 3.13Å
666A98Very high97.6Very high0 Ų021.3 Ų21.30%010%0.102CC..  trans-137.448.9-176.600000110.8L588 T608 Y663 D668 G669 I670L588-A666 HydrophobicContact CD1-CB 3.95Å; L588-A666 HydrophobicContact CD2-CB 4.04Å; T608-A666 CarbonylContact O-C 3.57Å; T608-A666 WeakPolarHBondContact O-CA 3.26Å; Y663-A666 WeakPolarHBondContact CD2-O 3.21Å; Y663-A666 WeakPolarHBondContact CE2-O 3.46Å; Y663-A666 CarbonylContact O-C 3.59Å; Y663-A666 WeakPolarHBondContact O-CA 3.44Å; Y663-A666 PolarHBondContact O-N 2.9Å; A666-D668 PolarHBondContact O-N 3.22Å; A666-G669 WeakPolarHBondContact O-CA 3.36Å; A666-G669 PolarHBondContact O-N 3.49Å; A666-I670 HydrophobicContact CB-CD1 3.9Å; A666-I670 HydrophobicContact CB-CG1 3.57Å
667L97.6Very high97.5Very high34 Ų3421.3 Ų21.318%0.17810%0.102CC..THydrogen-bonded Turntrans-60.8-13.6-175.6-70.4179.6000114.5V415 W416 T607 Y663 G669V415-L667 HydrophobicContact CG1-CD2 4.36Å; W416-L667 HydrophobicContact CZ2-CB 4.13Å; W416-L667 HydrophobicContact CZ2-CD2 4.33Å; T607-L667 HydrophobicContact CG2-CB 4.01Å; Y663-L667 HydrophobicContact CD1-CD2 4.31Å; Y663-L667 HydrophobicContact CE1-CD2 3.87Å; Y663-L667 HydrophobicContact CE2-CD2 4.42Å; Y663-L667 PolarHBondContact O-N 2.95Å; Y663-L667 PolarHBondContact OH-O 2.89Å; L667-G669 VanDerWaalsContact C-N 3.33Å
668D98.5Very high97.3Very high3 Ų323.1 Ų23.12%0.01611%0.113CC..THydrogen-bonded Turntrans-84.5-7.1170.4-164.662.4000113.6R187 V426 S427 A530 T608 S609 A666R187-D668 IonicContact CZ-OD1 2.85Å; R187-D668 IonicContact CZ-OD2 2.72Å; R187-D668 IonicContact NH1-OD1 3.51Å; R187-D668 PolarHBondContact NH1-OD1 3.47Å; R187-D668 IonicContact NH1-OD2 3.66Å; R187-D668 PolarHBondContact NH1-OD2 3.21Å; R187-D668 IonicContact NH2-OD1 2.68Å; R187-D668 IonicContact NH2-OD2 3.64Å; R187-D668 PolarHBondContact NH2-OD2 3.32Å; V426-D668 CarbonylContact C-O 3.48Å; S427-D668 WeakPolarHBondContact CA-O 3.49Å; S427-D668 WeakPolarHBondContact CB-O 3.49Å; S427-D668 WeakPolarHBondContact CB-OD1 3.37Å; S427-D668 PolarHBondContact OG-O 3.19Å; S427-D668 PolarHBondContact OG-OD1 3.11Å; A530-D668 HydrophobicContact CB-CB 4.31Å; A530-D668 VanDerWaalsContact CB-CG 3.48Å; A530-D668 VanDerWaalsContact CB-OD1 3.23Å; A530-D668 WeakPolarHBondContact CB-OD1 3.2Å; T608-D668 VanDerWaalsContact O-CB 3.27Å; T608-D668 WeakPolarHBondContact O-CB 3.41Å; T608-D668 PolarHBondContact O-N 3.24Å; S609-D668 WeakPolarHBondContact CB-OD2 3.33Å; S609-D668 PolarHBondContact OG-OD2 2.77Å; S609-D668 VanDerWaalsContact OG-OD2 3.07Å; A666-D668 PolarHBondContact O-N 3.22Å
669G98.2Very high97.1Very high0 Ų028.7 Ų28.70%014%0.143CC..EExtended strand (participates in β ladder)trans117155.116600000115.6V426 S609 I610 A666 L667V426-G669 VanDerWaalsContact O-CA 3.3Å; V426-G669 WeakPolarHBondContact O-CA 3.44Å; S609-G669 CarbonylContact C-O 3.59Å; S609-G669 WeakPolarHBondContact CA-O 3.3Å; S609-G669 WeakPolarHBondContact CB-O 3.47Å; I610-G669 PolarHBondContact N-O 3.35Å; A666-G669 WeakPolarHBondContact O-CA 3.36Å; A666-G669 PolarHBondContact O-N 3.49Å; L667-G669 VanDerWaalsContact C-N 3.33Å
670I98.7Very high97Very high6 Ų628.8 Ų28.83%0.03115%0.145CC..EExtended strand (participates in β ladder)trans-118.9107.6177.2-58.3168.7000108.3I610 A640 L661 A666 H705 H706I610-I670 HydrophobicContact CD1-CG1 4.45Å; I610-I670 HydrophobicContact CD1-CG2 4.37Å; A640-I670 HydrophobicContact CB-CG2 3.51Å; L661-I670 HydrophobicContact CB-CD1 3.87Å; L661-I670 HydrophobicContact CD1-CG2 3.88Å; A666-I670 HydrophobicContact CB-CD1 3.9Å; A666-I670 HydrophobicContact CB-CG1 3.57Å; I670-H705 HydrophobicContact CB-CB 4.03Å; I670-H705 HydrophobicContact CD1-CB 4.5Å; I670-H705 PolarHBondContact N-ND1 2.89Å; I670-H706 WeakPolarHBondContact O-CB 3.41Å
671S98.5Very high96.8Very high0 Ų024.5 Ų24.50%013%0.127CC..  trans-88.9129.9-176.6-172.20000111.9I610 A640 G738I610-S671 PolarHBondContact O-N 3.28Å; I610-S671 VanDerWaalsContact O-N 3.08Å; A640-S671 WeakPolarHBondContact CA-O 3.42Å; A640-S671 VanDerWaalsContact CB-O 3.3Å; A640-S671 WeakPolarHBondContact CB-O 3.32Å; A640-S671 PolarHBondContact N-O 3.49Å; S671-G738 PolarHBondContact OG-N 2.66Å
672N98.1Very high96.7Very high0 Ų024.4 Ų24.40%013%0.127CC..  trans-129.4133.4175.9-178.622.9000109.6L655 L658 Q674 Y699 H706 L707 N708L655-N672 WeakPolarHBondContact CD2-ND2 3.17Å; L658-N672 HydrophobicContact CD2-CB 3.34Å; L658-N672 WeakPolarHBondContact CD2-ND2 3.33Å; L658-N672 WeakPolarHBondContact CD2-OD1 3.48Å; N672-Q674 PolarHBondContact OD1-NE2 2.97Å; N672-Y699 PolarHBondContact ND2-OH 3.43Å; N672-H706 WeakPolarHBondContact CB-O 3.31Å; N672-H706 PolarHBondContact N-ND1 3.18Å; N672-H706 VanDerWaalsContact N-ND1 3.14Å; N672-H706 PolarHBondContact O-CE1 3.01Å; N672-H706 PolarHBondContact O-ND1 2.94Å; N672-L707 HydrophobicContact CB-CD1 4.43Å; N672-L707 VanDerWaalsContact ND2-CD1 3.27Å; N672-L707 WeakPolarHBondContact ND2-CD1 3.24Å; N672-N708 PolarHBondContact O-N 3.08Å
673T97.4Very high96.6Very high6 Ų631 Ų314%0.03716%0.156CC..EExtended strand (participates in β ladder)trans-124.4110.3177.7-54.30000111.4N641 N708 R735N641-T673 PolarHBondContact ND2-O 2.95Å; N641-T673 PolarHBondContact OD1-N 3.34Å; T673-N708 HydrophobicContact CG2-CB 3.93Å; T673-N708 PolarHBondContact OG1-ND2 2.84Å; T673-N708 VanDerWaalsContact OG1-ND2 3.15Å; T673-R735 WeakPolarHBondContact CG2-O 3.42Å
674Q96.8Very high96.5Very high9 Ų934.7 Ų34.74%0.04218%0.177CC..EExtended strand (participates in β ladder)trans-112.8136.2-177.9-64.4-64.7-29.600110.4E647 L651 S654 L655 N672 L707 N708 N710 H760E647-Q674 PolarHBondContact OE1-NE2 3.42Å; E647-Q674 PolarHBondContact OE1-OE1 2.91Å; L651-Q674 HydrophobicContact CD1-CB 3.82Å; L651-Q674 HydrophobicContact CD1-CG 3.91Å; S654-Q674 PolarHBondContact OG-NE2 3.31Å; L655-Q674 HydrophobicContact CD2-CG 3.9Å; N672-Q674 PolarHBondContact OD1-NE2 2.97Å; Q674-L707 HydrophobicContact CB-CD1 3.96Å; Q674-L707 HydrophobicContact CG-CD1 3.63Å; Q674-N708 PolarHBondContact N-O 2.73Å; Q674-N710 PolarHBondContact O-N 2.74Å; Q674-H760 PolarHBondContact OE1-CD2 3.43Å; Q674-H760 PolarHBondContact OE1-NE2 3.21Å
675S96.7Very high96.5Very high7 Ų733.3 Ų33.35%0.04917%0.17CC..EExtended strand (participates in β ladder)trans-119.5129175.4-56.30000109.2N710 H760S675-N710 WeakPolarHBondContact CA-O 3.28Å; S675-N710 WeakPolarHBondContact OG-CB 3.3Å; S675-N710 PolarHBondContact OG-ND2 3.44Å; S675-H760 PolarHBondContact O-CD2 2.93Å; S675-H760 PolarHBondContact O-N 3.39Å
676I96.5Very high96.4Very high6 Ų636 Ų363%0.03119%0.19CC..EExtended strand (participates in β ladder)trans-126.7139.9179.3-173.2159.7000110.4L651 A680 L681 N710 V711 F712 H760 M763L651-I676 HydrophobicContact CD2-CD1 3.68Å; I676-A680 HydrophobicContact CD1-CB 4.17Å; I676-A680 HydrophobicContact CG1-CB 3.9Å; I676-L681 HydrophobicContact CD1-CB 4.2Å; I676-L681 HydrophobicContact CD1-CD1 4.31Å; I676-L681 HydrophobicContact CG1-CB 4.45Å; I676-N710 PolarHBondContact N-O 3.32Å; I676-V711 HydrophobicContact CG2-CG2 4.25Å; I676-V711 WeakPolarHBondContact O-CA 3.47Å; I676-F712 PolarHBondContact O-N 2.81Å; I676-H760 HydrophobicContact CB-CB 4.4Å; I676-H760 HydrophobicContact CG1-CB 4.24Å; I676-M763 HydrophobicContact CD1-CG 4.41Å
677N94.9Very high96.4Very high40 Ų4039.1 Ų39.121%0.21420%0.204CC..  trans-68.5137.6172.4-69.9-22.5000109.6D679 A680 L681 G713 H760N677-D679 PolarHBondContact O-N 2.89Å; N677-D679 VanDerWaalsContact O-N 3.16Å; N677-A680 HydrophobicContact CB-CB 4.2Å; N677-A680 WeakPolarHBondContact O-CA 3.5Å; N677-A680 WeakPolarHBondContact O-CB 3.41Å; N677-A680 PolarHBondContact O-N 3.23Å; N677-L681 PolarHBondContact O-N 3.46Å; N677-G713 WeakPolarHBondContact OD1-CA 3.17Å; N677-H760 PolarHBondContact N-O 2.89Å
678P94.9Very high96.4Very high37 Ų3740 Ų4024%0.2421%0.205CC..Hα-helixtrans-52.9-40.8-179.2-27.533.2000113.9A680 L681 G682 R688 V711P678-A680 VanDerWaalsContact C-N 3.26Å; P678-A680 PolarHBondContact O-N 2.89Å; P678-L681 PolarHBondContact O-N 3.48Å; P678-L681 VanDerWaalsContact O-N 3.14Å; P678-G682 PolarHBondContact O-N 3.37Å; P678-G682 VanDerWaalsContact O-N 3.11Å; P678-G682 VanDerWaalsContact O-O 3.08Å; P678-R688 PolarHBondContact O-NE 2.81Å; P678-V711 HydrophobicContact CB-CG1 4.38Å; P678-V711 HydrophobicContact CG-CG1 4.17Å
679D93.9Very high96.4Very high122 Ų12240.6 Ų40.665%0.65221%0.209SC*.Hα-helixtrans-71.1-20179.6-64.3-18.1000113.7N677 L681 R688N677-D679 PolarHBondContact O-N 2.89Å; N677-D679 VanDerWaalsContact O-N 3.16Å; D679-L681 VanDerWaalsContact C-N 3.34Å; D679-R688 IonicContact OD1-NH2 3.29Å; D679-R688 PolarHBondContact OD1-NH2 3.19Å
680A94.8Very high96.4Very high17 Ų1746.3 Ų46.314%0.1424%0.236CC..Hα-helixtrans-80.3-22173.500000111.9I676 N677 P678 A761I676-A680 HydrophobicContact CD1-CB 4.17Å; I676-A680 HydrophobicContact CG1-CB 3.9Å; N677-A680 HydrophobicContact CB-CB 4.2Å; N677-A680 WeakPolarHBondContact O-CA 3.5Å; N677-A680 WeakPolarHBondContact O-CB 3.41Å; N677-A680 PolarHBondContact O-N 3.23Å; P678-A680 VanDerWaalsContact C-N 3.26Å; P678-A680 PolarHBondContact O-N 2.89Å; A680-A761 VanDerWaalsContact CB-C 3.43Å
681L95.2Very high96.4Very high1 Ų147.4 Ų47.41%0.00524%0.241CC..Hα-helixtrans-87.9-34.2177.8-173.264.4000112I399 I676 N677 P678 D679 R688 N691 L692 V711I399-L681 HydrophobicContact CD1-CD2 4.27Å; I399-L681 HydrophobicContact CG1-CD2 4.02Å; I676-L681 HydrophobicContact CD1-CB 4.2Å; I676-L681 HydrophobicContact CD1-CD1 4.31Å; I676-L681 HydrophobicContact CG1-CB 4.45Å; N677-L681 PolarHBondContact O-N 3.46Å; P678-L681 PolarHBondContact O-N 3.48Å; P678-L681 VanDerWaalsContact O-N 3.14Å; D679-L681 VanDerWaalsContact C-N 3.34Å; L681-R688 HydrophobicContact CB-CG 4.22Å; L681-R688 HydrophobicContact CD2-CB 3.98Å; L681-R688 HydrophobicContact CD2-CG 4.32Å; L681-R688 HydrophobicContact CG-CB 4.1Å; L681-R688 HydrophobicContact CG-CG 4.19Å; L681-N691 HydrophobicContact CD1-CB 4Å; L681-N691 VanDerWaalsContact O-CB 3.3Å; L681-N691 WeakPolarHBondContact O-CB 3.32Å; L681-N691 PolarHBondContact O-ND2 2.92Å; L681-L692 HydrophobicContact CD1-CB 4.1Å; L681-L692 HydrophobicContact CD2-CB 4.07Å; L681-V711 HydrophobicContact CD2-CG1 4.19Å; L681-V711 HydrophobicContact CD2-CG2 4.41Å
682G95.6Very high96.4Very high3 Ų347.6 Ų47.63%0.03124%0.242CC..  trans173.5163.1176.500000112.9P678 R688P678-G682 PolarHBondContact O-N 3.37Å; P678-G682 VanDerWaalsContact O-N 3.11Å; P678-G682 VanDerWaalsContact O-O 3.08Å; G682-R688 PolarHBondContact O-NE 2.53Å; G682-R688 PolarHBondContact O-NH2 3.43Å
683H93.7Very high96.4Very high154 Ų15447.7 Ų47.771%0.71324%0.243SC*.SBendtrans-85.3-23-176.8-61.8-49.6000113.7E687H683-E687 WeakPolarHBondContact CB-OE2 3.5Å; H683-E687 IonicContact CD2-OE2 3.23Å; H683-E687 PolarHBondContact CD2-OE2 2.88Å; H683-E687 IonicContact CG-OE2 2.97Å; H683-E687 PolarHBondContact N-OE2 3.25Å
684D95.8Very high96.4Very high88 Ų8851.4 Ų51.447%0.47126%0.263SS..SBendtrans-135.3177.5173.558.649.8000111.5D686 E687 R688D684-D686 PolarHBondContact OD1-N 3.43Å; D684-E687 WeakPolarHBondContact OD1-CB 3.33Å; D684-E687 PolarHBondContact OD1-N 2.99Å; D684-R688 WeakPolarHBondContact O-CB 3.22Å; D684-R688 WeakPolarHBondContact O-CD 3.49Å; D684-R688 WeakPolarHBondContact O-CG 3.42Å; D684-R688 PolarHBondContact O-N 3.2Å; D684-R688 VanDerWaalsContact O-N 3.11Å
685E95.2Very high96.5Very high96 Ų9651.4 Ų51.445%0.44926%0.263SS..Hα-helixtrans-64.5-46.3-176.6-173.8174123.200112.1K396 E687 R688 V689K396-E685 WeakPolarHBondContact CE-OE1 3.04Å; E685-E687 PolarHBondContact O-N 3.3Å; E685-R688 PolarHBondContact O-N 3.48Å; E685-R688 VanDerWaalsContact O-N 3.17Å; E685-V689 WeakPolarHBondContact O-CG2 3.29Å; E685-V689 PolarHBondContact O-N 3.15Å
686D96.5Very high96.6Very high128 Ų12851.1 Ų51.168%0.68426%0.261SS*.Hα-helixtrans-60.9-46.3-178.7-66.7-20.2000110.7D684 R688 V689 E690D684-D686 PolarHBondContact OD1-N 3.43Å; D686-R688 VanDerWaalsContact C-N 3.33Å; D686-R688 PolarHBondContact O-N 2.79Å; D686-V689 PolarHBondContact O-N 3.23Å; D686-E690 WeakPolarHBondContact O-CB 3.08Å; D686-E690 PolarHBondContact O-N 2.81Å
687E97.2Very high96.7Very high64 Ų6452 Ų5230%0.29927%0.266SS..Hα-helixtrans-63.3-38.7176.7-175.5178.5-161.300111.8H683 D684 E685 N691H683-E687 WeakPolarHBondContact CB-OE2 3.5Å; H683-E687 IonicContact CD2-OE2 3.23Å; H683-E687 PolarHBondContact CD2-OE2 2.88Å; H683-E687 IonicContact CG-OE2 2.97Å; H683-E687 PolarHBondContact N-OE2 3.25Å; D684-E687 WeakPolarHBondContact OD1-CB 3.33Å; D684-E687 PolarHBondContact OD1-N 2.99Å; E685-E687 PolarHBondContact O-N 3.3Å; E687-N691 WeakPolarHBondContact CG-ND2 3.29Å; E687-N691 VanDerWaalsContact O-CB 3.28Å; E687-N691 WeakPolarHBondContact O-CB 3.12Å; E687-N691 VanDerWaalsContact O-CG 3.29Å; E687-N691 PolarHBondContact O-N 2.91Å; E687-N691 PolarHBondContact O-ND2 3.42Å
688R98Very high96.8Very high52 Ų5251.7 Ų51.720%0.19627%0.272CS..Hα-helixtrans-66.3-42.1177.8-73165.2-174.71603.1111.9I399 P678 D679 L681 G682 D684 E685 D686 L692I399-R688 HydrophobicContact CD1-CB 3.73Å; I399-R688 HydrophobicContact CG1-CB 4.48Å; P678-R688 PolarHBondContact O-NE 2.81Å; D679-R688 IonicContact OD1-NH2 3.29Å; D679-R688 PolarHBondContact OD1-NH2 3.19Å; L681-R688 HydrophobicContact CB-CG 4.22Å; L681-R688 HydrophobicContact CD2-CB 3.98Å; L681-R688 HydrophobicContact CD2-CG 4.32Å; L681-R688 HydrophobicContact CG-CB 4.1Å; L681-R688 HydrophobicContact CG-CG 4.19Å; G682-R688 PolarHBondContact O-NE 2.53Å; G682-R688 PolarHBondContact O-NH2 3.43Å; D684-R688 WeakPolarHBondContact O-CB 3.22Å; D684-R688 WeakPolarHBondContact O-CD 3.49Å; D684-R688 WeakPolarHBondContact O-CG 3.42Å; D684-R688 PolarHBondContact O-N 3.2Å; D684-R688 VanDerWaalsContact O-N 3.11Å; E685-R688 PolarHBondContact O-N 3.48Å; E685-R688 VanDerWaalsContact O-N 3.17Å; D686-R688 VanDerWaalsContact C-N 3.33Å; D686-R688 PolarHBondContact O-N 2.79Å; R688-L692 VanDerWaalsContact O-CB 3.3Å; R688-L692 WeakPolarHBondContact O-CB 3.48Å; R688-L692 PolarHBondContact O-N 3.36Å
689V98.3Very high97Very high16 Ų1650.2 Ų50.210%0.09726%0.262CS..Hα-helixtrans-62-52.5176.3171.20000109.6D392 A395 K396 I399 E685 D686 N691 L692 T693D392-V689 HydrophobicContact CB-CG1 3.75Å; A395-V689 HydrophobicContact CB-CG1 4.19Å; K396-V689 HydrophobicContact CB-CG2 4.02Å; I399-V689 HydrophobicContact CD1-CB 4.46Å; I399-V689 HydrophobicContact CD1-CG2 3.79Å; E685-V689 WeakPolarHBondContact O-CG2 3.29Å; E685-V689 PolarHBondContact O-N 3.15Å; D686-V689 PolarHBondContact O-N 3.23Å; V689-N691 PolarHBondContact O-N 3.42Å; V689-L692 PolarHBondContact O-N 2.93Å; V689-T693 PolarHBondContact O-N 3.03Å; V689-T693 PolarHBondContact O-OG1 2.98Å
690E98Very high97.2Very high121 Ų12144.5 Ų44.557%0.56523%0.231SC*.Hα-helixtrans-56.7-48.9179.7-178.8178.6-176.600111.4D686 L692 T693 N694D686-E690 WeakPolarHBondContact O-CB 3.08Å; D686-E690 PolarHBondContact O-N 2.81Å; E690-L692 PolarHBondContact O-N 3.23Å; E690-T693 PolarHBondContact O-N 3.37Å; E690-N694 WeakPolarHBondContact O-CB 3.43Å; E690-N694 VanDerWaalsContact O-CG 3.23Å; E690-N694 PolarHBondContact O-N 2.95Å; E690-N694 PolarHBondContact O-ND2 3.12Å; E690-N694 VanDerWaalsContact O-ND2 3.15Å
691N98.2Very high97.4Very high28 Ų2848.4 Ų48.415%0.1525%0.249CC..Hα-helixtrans-66.6-38.8-179.2-74.3-25.4000112.4L681 E687 V689 N694 V695 M763L681-N691 HydrophobicContact CD1-CB 4Å; L681-N691 VanDerWaalsContact O-CB 3.3Å; L681-N691 WeakPolarHBondContact O-CB 3.32Å; L681-N691 PolarHBondContact O-ND2 2.92Å; E687-N691 WeakPolarHBondContact CG-ND2 3.29Å; E687-N691 VanDerWaalsContact O-CB 3.28Å; E687-N691 WeakPolarHBondContact O-CB 3.12Å; E687-N691 VanDerWaalsContact O-CG 3.29Å; E687-N691 PolarHBondContact O-N 2.91Å; E687-N691 PolarHBondContact O-ND2 3.42Å; V689-N691 PolarHBondContact O-N 3.42Å; N691-N694 PolarHBondContact O-N 3.32Å; N691-V695 WeakPolarHBondContact O-CB 3.32Å; N691-V695 VanDerWaalsContact O-CG2 3.24Å; N691-V695 WeakPolarHBondContact O-CG2 3.47Å; N691-V695 PolarHBondContact O-N 2.86Å; N691-M763 HydrophobicContact CB-CE 4.38Å; N691-M763 HydrophobicContact CB-SD 4.3Å
692L98.4Very high97.5Very high5 Ų552.7 Ų52.73%0.02627%0.269CS..Hα-helixtrans-66.6-43.4176.3-178.556.3000111.4A395 I399 L681 R688 V689 E690 N694 V695 L696 V709A395-L692 HydrophobicContact CB-CB 4.22Å; A395-L692 HydrophobicContact CB-CD2 3.93Å; A395-L692 HydrophobicContact CB-CG 4.1Å; I399-L692 HydrophobicContact CD1-CD2 4.28Å; I399-L692 HydrophobicContact CG1-CD2 4Å; L681-L692 HydrophobicContact CD1-CB 4.1Å; L681-L692 HydrophobicContact CD2-CB 4.07Å; R688-L692 VanDerWaalsContact O-CB 3.3Å; R688-L692 WeakPolarHBondContact O-CB 3.48Å; R688-L692 PolarHBondContact O-N 3.36Å; V689-L692 PolarHBondContact O-N 2.93Å; E690-L692 PolarHBondContact O-N 3.23Å; L692-N694 VanDerWaalsContact C-N 3.32Å; L692-N694 PolarHBondContact O-N 3.11Å; L692-V695 PolarHBondContact O-N 3.07Å; L692-L696 HydrophobicContact CD1-CD1 4.34Å; L692-L696 HydrophobicContact CD1-CG 4.26Å; L692-L696 HydrophobicContact CG-CD1 4.07Å; L692-L696 HydrophobicContact CG-CG 4.47Å; L692-L696 VanDerWaalsContact O-CG 3.24Å; L692-L696 WeakPolarHBondContact O-CG 3.49Å; L692-L696 PolarHBondContact O-N 3.48Å; L692-V709 HydrophobicContact CD1-CG1 3.93Å; L692-V709 HydrophobicContact CD1-CG2 4.44Å; L692-V709 HydrophobicContact CD2-CG1 4.08Å
693T98.4Very high97.5Very high1 Ų153.6 Ų53.61%0.00628%0.279CS..Hα-helixtrans-58-45.8173.9-63.30000110.8Y382 K391 D392 V689 E690 V695 L696 D697Y382-T693 PolarHBondContact OH-O 3.49Å; K391-T693 HydrophobicContact CB-CG2 3.98Å; K391-T693 HydrophobicContact CD-CG2 4.15Å; D392-T693 PolarHBondContact OD1-OG1 3.35Å; V689-T693 PolarHBondContact O-N 3.03Å; V689-T693 PolarHBondContact O-OG1 2.98Å; E690-T693 PolarHBondContact O-N 3.37Å; T693-V695 PolarHBondContact O-N 2.77Å; T693-L696 PolarHBondContact O-N 3.27Å; T693-D697 WeakPolarHBondContact O-CB 3.37Å; T693-D697 PolarHBondContact O-N 3.43Å
694N98.1Very high97.7Very high85 Ų8546.3 Ų46.346%0.45525%0.246SC..Hα-helixtrans-62.4-39176.9-73.7-33000112.9E690 N691 L692 G698E690-N694 WeakPolarHBondContact O-CB 3.43Å; E690-N694 VanDerWaalsContact O-CG 3.23Å; E690-N694 PolarHBondContact O-N 2.95Å; E690-N694 PolarHBondContact O-ND2 3.12Å; E690-N694 VanDerWaalsContact O-ND2 3.15Å; N691-N694 PolarHBondContact O-N 3.32Å; L692-N694 VanDerWaalsContact C-N 3.32Å; L692-N694 PolarHBondContact O-N 3.11Å; N694-G698 PolarHBondContact O-N 3.17Å
695V98.3Very high97.9Very high9 Ų942.3 Ų42.36%0.05522%0.224CC..Hα-helixtrans-63.5-45.3174.5166.50000110.8L651 L652 L655 N691 L692 T693 G698 Y699 M763L651-V695 HydrophobicContact CD2-CG1 4.23Å; L652-V695 HydrophobicContact CD2-CG2 4.08Å; L655-V695 HydrophobicContact CD1-CG1 3.47Å; L655-V695 VanDerWaalsContact CD1-CG1 3.47Å; N691-V695 WeakPolarHBondContact O-CB 3.32Å; N691-V695 VanDerWaalsContact O-CG2 3.24Å; N691-V695 WeakPolarHBondContact O-CG2 3.47Å; N691-V695 PolarHBondContact O-N 2.86Å; L692-V695 PolarHBondContact O-N 3.07Å; T693-V695 PolarHBondContact O-N 2.77Å; V695-G698 PolarHBondContact O-N 3.47Å; V695-Y699 VanDerWaalsContact O-CB 3.29Å; V695-Y699 WeakPolarHBondContact O-CB 3.15Å; V695-Y699 PolarHBondContact O-N 3.34Å; V695-M763 HydrophobicContact CG2-SD 4.32Å
696L98.6Very high98Very high0 Ų037.8 Ų37.80%020%0.203CC..Hα-helixtrans-63.5-47.3178.5-67.4166000111.1Y382 Y406 L692 T693 Y699 F700 L707 V709Y382-L696 HydrophobicContact CE1-CB 3.96Å; Y382-L696 HydrophobicContact CE2-CB 3.86Å; Y382-L696 HydrophobicContact CE2-CD1 3.98Å; Y382-L696 HydrophobicContact CE2-CG 4.48Å; Y382-L696 VanDerWaalsContact CZ-CB 3.5Å; Y382-L696 WeakPolarHBondContact OH-CB 3.19Å; Y406-L696 HydrophobicContact CD1-CD1 4.21Å; Y406-L696 HydrophobicContact CD1-CD2 4.23Å; Y406-L696 HydrophobicContact CD2-CD2 3.85Å; Y406-L696 HydrophobicContact CE1-CD1 3.77Å; Y406-L696 HydrophobicContact CE1-CD2 4.5Å; Y406-L696 HydrophobicContact CE2-CD1 4.19Å; Y406-L696 HydrophobicContact CE2-CD2 4.15Å; Y406-L696 HydrophobicContact CG-CD2 3.88Å; L692-L696 HydrophobicContact CD1-CD1 4.34Å; L692-L696 HydrophobicContact CD1-CG 4.26Å; L692-L696 HydrophobicContact CG-CD1 4.07Å; L692-L696 HydrophobicContact CG-CG 4.47Å; L692-L696 VanDerWaalsContact O-CG 3.24Å; L692-L696 WeakPolarHBondContact O-CG 3.49Å; L692-L696 PolarHBondContact O-N 3.48Å; T693-L696 PolarHBondContact O-N 3.27Å; L696-Y699 PolarHBondContact O-N 3.15Å; L696-F700 HydrophobicContact CB-CD2 4.3Å; L696-F700 HydrophobicContact CB-CE2 4.45Å; L696-F700 HydrophobicContact CD2-CD2 4.4Å; L696-F700 HydrophobicContact CD2-CE2 3.74Å; L696-F700 WeakPolarHBondContact O-CB 3.37Å; L696-F700 WeakPolarHBondContact O-CD2 3.46Å; L696-F700 PolarHBondContact O-N 3.47Å; L696-L707 HydrophobicContact CD2-CD2 3.81Å; L696-V709 HydrophobicContact CD2-CG2 4.39Å
697D98.6Very high98.1Very high25 Ų2531.9 Ų31.913%0.13417%0.171CC..Hα-helixtrans-56-53175.6-78.3-10.4000110.6Y382 S384 K391 T693 Y699 F700 D701Y382-D697 VanDerWaalsContact CE1-OD1 3.29Å; Y382-D697 WeakPolarHBondContact CE1-OD1 3.44Å; Y382-D697 VanDerWaalsContact CZ-OD1 3.28Å; Y382-D697 PolarHBondContact OH-OD1 3.45Å; S384-D697 WeakPolarHBondContact CA-OD1 3.4Å; S384-D697 WeakPolarHBondContact CB-OD1 3.16Å; K391-D697 IonicContact NZ-OD1 2.72Å; K391-D697 IonicContact NZ-OD2 2.67Å; K391-D697 PolarHBondContact NZ-OD2 3.23Å; T693-D697 WeakPolarHBondContact O-CB 3.37Å; T693-D697 PolarHBondContact O-N 3.43Å; D697-Y699 VanDerWaalsContact C-N 3.34Å; D697-Y699 PolarHBondContact O-N 2.87Å; D697-F700 PolarHBondContact O-N 2.75Å; D697-D701 WeakPolarHBondContact O-CB 3.46Å; D697-D701 VanDerWaalsContact O-CG 3.25Å; D697-D701 PolarHBondContact O-N 3.43Å
698G98.1Very high98.2Very high33 Ų3328.8 Ų28.834%0.3416%0.157SC..Hα-helixtrans-63.3-34.7-179.400000114.4N694 V695 Q702N694-G698 PolarHBondContact O-N 3.17Å; V695-G698 PolarHBondContact O-N 3.47Å; G698-Q702 WeakPolarHBondContact O-CG 3.32Å; G698-Q702 PolarHBondContact O-NE2 3.11Å
699Y98.5Very high98.2Very high6 Ų626.6 Ų26.62%0.02415%0.149CC..Hα-helixtrans-73.1-46.7178.6-177.9-122000112L655 L658 T659 N672 V695 L696 D697 Q702 A704 H706 L707L655-Y699 HydrophobicContact CB-CD2 3.68Å; L655-Y699 HydrophobicContact CB-CE2 3.99Å; L655-Y699 HydrophobicContact CB-CG 4.49Å; L655-Y699 HydrophobicContact CD2-CD2 3.86Å; L655-Y699 HydrophobicContact CD2-CE1 4.43Å; L655-Y699 HydrophobicContact CD2-CE2 3.76Å; L655-Y699 HydrophobicContact CD2-CG 4.22Å; L655-Y699 HydrophobicContact CG-CD2 4.21Å; L655-Y699 HydrophobicContact CG-CE2 4.45Å; L655-Y699 WeakPolarHBondContact O-CE2 3.29Å; L658-Y699 HydrophobicContact CB-CE2 4.06Å; T659-Y699 HydrophobicContact CG2-CD2 3.66Å; T659-Y699 HydrophobicContact CG2-CE2 3.94Å; N672-Y699 PolarHBondContact ND2-OH 3.43Å; V695-Y699 VanDerWaalsContact O-CB 3.29Å; V695-Y699 WeakPolarHBondContact O-CB 3.15Å; V695-Y699 PolarHBondContact O-N 3.34Å; L696-Y699 PolarHBondContact O-N 3.15Å; D697-Y699 VanDerWaalsContact C-N 3.34Å; D697-Y699 PolarHBondContact O-N 2.87Å; Y699-Q702 PolarHBondContact O-N 3.39Å; Y699-A704 HydrophobicContact CD1-CB 3.88Å; Y699-A704 HydrophobicContact CD2-CB 3.66Å; Y699-A704 HydrophobicContact CE1-CB 3.49Å; Y699-A704 VanDerWaalsContact CE1-CB 3.49Å; Y699-A704 HydrophobicContact CE2-CB 3.26Å; Y699-A704 HydrophobicContact CG-CB 3.98Å; Y699-H706 PolarHBondContact OH-O 2.9Å; Y699-L707 HydrophobicContact CD1-CB 4.24Å; Y699-L707 HydrophobicContact CD1-CD2 4.3Å; Y699-L707 HydrophobicContact CE1-CB 3.93Å; Y699-L707 HydrophobicContact CE1-CD1 4.43Å
700F98.6Very high98.2Very high3 Ų326 Ų261%0.01315%0.145CC..Hα-helixtrans-80.5-31.4-174.9-68.6-53.8000113.4Y382 Y406 N408 L696 D697 Q702 G703 A704 L707Y382-F700 HydrophobicContact CD1-CB 4.02Å; Y382-F700 AromaticContact CD1-CD2 3.25Å; Y382-F700 HydrophobicContact CD1-CD2 3.25Å; Y382-F700 AromaticContact CD1-CE2 4Å; Y382-F700 HydrophobicContact CD1-CE2 4Å; Y382-F700 AromaticContact CD1-CG 3.95Å; Y382-F700 HydrophobicContact CD1-CG 3.95Å; Y382-F700 AromaticContact CE1-CD2 3.88Å; Y382-F700 HydrophobicContact CE1-CD2 3.88Å; Y382-F700 AromaticContact CG-CD2 3.67Å; Y382-F700 HydrophobicContact CG-CD2 3.67Å; Y382-F700 AromaticContact CG-CE2 3.93Å; Y382-F700 HydrophobicContact CG-CE2 3.93Å; Y406-F700 HydrophobicContact CG-CE2 4.4Å; N408-F700 HydrophobicContact CB-CD1 3.5Å; N408-F700 VanDerWaalsContact CB-CD1 3.5Å; N408-F700 HydrophobicContact CB-CE1 3.96Å; N408-F700 HydrophobicContact CB-CG 4.27Å; N408-F700 PolarHBondContact ND2-O 3.43Å; L696-F700 HydrophobicContact CB-CD2 4.3Å; L696-F700 HydrophobicContact CB-CE2 4.45Å; L696-F700 HydrophobicContact CD2-CD2 4.4Å; L696-F700 HydrophobicContact CD2-CE2 3.74Å; L696-F700 WeakPolarHBondContact O-CB 3.37Å; L696-F700 WeakPolarHBondContact O-CD2 3.46Å; L696-F700 PolarHBondContact O-N 3.47Å; D697-F700 PolarHBondContact O-N 2.75Å; F700-Q702 PolarHBondContact O-N 2.77Å; F700-G703 PolarHBondContact O-N 2.92Å; F700-A704 WeakPolarHBondContact CD1-O 3.35Å; F700-L707 HydrophobicContact CZ-CB 3.94Å
701D98.3Very high98.1Very high98 Ų9820.6 Ų20.652%0.52412%0.121SC..THydrogen-bonded Turntrans-63.1-23.2172.7-78-9.6000112.4S384 D697 G703S384-D701 WeakPolarHBondContact CB-OD1 3.06Å; S384-D701 PolarHBondContact OG-OD1 2.69Å; D697-D701 WeakPolarHBondContact O-CB 3.46Å; D697-D701 VanDerWaalsContact O-CG 3.25Å; D697-D701 PolarHBondContact O-N 3.43Å; D701-G703 VanDerWaalsContact C-N 3.29Å
702Q97.5Very high98Very high91 Ų9119.6 Ų19.643%0.42512%0.115SC..THydrogen-bonded Turntrans-84.31.5174.2-69.9-176.479.200113.8N656 T659 G698 Y699 F700N656-Q702 PolarHBondContact OD1-NE2 3.17Å; T659-Q702 HydrophobicContact CG2-CB 3.61Å; T659-Q702 HydrophobicContact CG2-CG 4.45Å; G698-Q702 WeakPolarHBondContact O-CG 3.32Å; G698-Q702 PolarHBondContact O-NE2 3.11Å; Y699-Q702 PolarHBondContact O-N 3.39Å; F700-Q702 PolarHBondContact O-N 2.77Å
703G96.3Very high97.7Very high23 Ų2320 Ų2024%0.23712%0.121CC..THydrogen-bonded Turntrans89.112173.300000115.7F700 D701F700-G703 PolarHBondContact O-N 2.92Å; D701-G703 VanDerWaalsContact C-N 3.29Å
704A97.9Very high97.5Very high1 Ų123.6 Ų23.61%0.00814%0.137CC..  trans-66.2152.7174.200000112.1N408 T659 Y699 F700N408-A704 WeakPolarHBondContact CB-O 3.43Å; N408-A704 PolarHBondContact ND2-O 3.34Å; T659-A704 HydrophobicContact CG2-CB 4.04Å; Y699-A704 HydrophobicContact CD1-CB 3.88Å; Y699-A704 HydrophobicContact CD2-CB 3.66Å; Y699-A704 HydrophobicContact CE1-CB 3.49Å; Y699-A704 VanDerWaalsContact CE1-CB 3.49Å; Y699-A704 HydrophobicContact CE2-CB 3.26Å; Y699-A704 HydrophobicContact CG-CB 3.98Å; F700-A704 WeakPolarHBondContact CD1-O 3.35Å
705H98.4Very high97.4Very high4 Ų426 Ų262%0.01915%0.145CC..  trans-85.6-57.4-170.1-179.2-99.1000114.6E407 N408 V426 Y663 I670E407-H705 CarbonylContact C-O 3.4Å; E407-H705 VanDerWaalsContact CA-O 3.32Å; E407-H705 WeakPolarHBondContact CA-O 3.38Å; E407-H705 IonicContact OE2-CE1 3.67Å; E407-H705 PolarHBondContact OE2-CE1 3.34Å; E407-H705 IonicContact OE2-ND1 3.41Å; E407-H705 IonicContact OE2-NE2 2.77Å; N408-H705 WeakPolarHBondContact CB-O 3.34Å; N408-H705 PolarHBondContact N-O 3.46Å; V426-H705 PolarHBondContact O-CE1 3.48Å; Y663-H705 HydrophobicContact CD2-CB 4.19Å; Y663-H705 AromaticContact CD2-CD2 3.18Å; Y663-H705 WeakPolarHBondContact CD2-CD2 3.42Å; Y663-H705 AromaticContact CD2-CG 3.77Å; Y663-H705 AromaticContact CD2-NE2 3.84Å; Y663-H705 AromaticContact CE2-CD2 3.07Å; Y663-H705 WeakPolarHBondContact CE2-CD2 3Å; Y663-H705 AromaticContact CE2-CG 3.97Å; Y663-H705 AromaticContact CE2-NE2 3.23Å; Y663-H705 WeakPolarHBondContact CE2-NE2 3.22Å; Y663-H705 AromaticContact CG-CD2 3.77Å; Y663-H705 AromaticContact CZ-CD2 3.58Å; Y663-H705 AromaticContact CZ-NE2 3.6Å; I670-H705 HydrophobicContact CB-CB 4.03Å; I670-H705 HydrophobicContact CD1-CB 4.5Å; I670-H705 PolarHBondContact N-ND1 2.89Å
706H98.7Very high97.2Very high0 Ų029.8 Ų29.80%016%0.161CC..EExtended strand (participates in β ladder)trans-142.2149-169.3151.6-69.9000111.3Q405 Y406 E407 V426 I670 N672 Y699 N708Q405-H706 PolarHBondContact OE1-NE2 3.43Å; Q405-H706 VanDerWaalsContact OE1-NE2 3.11Å; Y406-H706 CarbonylContact O-C 3.32Å; Y406-H706 VanDerWaalsContact O-CA 3.28Å; Y406-H706 WeakPolarHBondContact O-CA 3.48Å; E407-H706 HydrophobicContact CG-CB 3.91Å; V426-H706 HydrophobicContact CG1-CB 3.71Å; V426-H706 WeakPolarHBondContact CG1-CD2 3.28Å; I670-H706 WeakPolarHBondContact O-CB 3.41Å; N672-H706 WeakPolarHBondContact CB-O 3.31Å; N672-H706 PolarHBondContact N-ND1 3.18Å; N672-H706 VanDerWaalsContact N-ND1 3.14Å; N672-H706 PolarHBondContact O-CE1 3.01Å; N672-H706 PolarHBondContact O-ND1 2.94Å; Y699-H706 PolarHBondContact OH-O 2.9Å; H706-N708 PolarHBondContact CE1-N 3.47Å; H706-N708 VanDerWaalsContact CE1-N 3.34Å; H706-N708 PolarHBondContact CE1-ND2 3.48Å; H706-N708 VanDerWaalsContact CE1-ND2 3.27Å; H706-N708 PolarHBondContact NE2-ND2 2.67Å
707L98.7Very high97.2Very high4 Ų429.8 Ų29.82%0.02116%0.161CC..EExtended strand (participates in β ladder)trans-138.7123.6171.3-171.962.3000111.8Y406 L655 N672 Q674 L696 Y699 F700 V709Y406-L707 PolarHBondContact N-O 3.18Å; Y406-L707 PolarHBondContact O-N 3.48Å; L655-L707 HydrophobicContact CD2-CD1 3.81Å; L655-L707 HydrophobicContact CD2-CD2 4.44Å; N672-L707 HydrophobicContact CB-CD1 4.43Å; N672-L707 VanDerWaalsContact ND2-CD1 3.27Å; N672-L707 WeakPolarHBondContact ND2-CD1 3.24Å; Q674-L707 HydrophobicContact CB-CD1 3.96Å; Q674-L707 HydrophobicContact CG-CD1 3.63Å; L696-L707 HydrophobicContact CD2-CD2 3.81Å; Y699-L707 HydrophobicContact CD1-CB 4.24Å; Y699-L707 HydrophobicContact CD1-CD2 4.3Å; Y699-L707 HydrophobicContact CE1-CB 3.93Å; Y699-L707 HydrophobicContact CE1-CD1 4.43Å; F700-L707 HydrophobicContact CZ-CB 3.94Å; L707-V709 HydrophobicContact CD2-CG2 3.78Å; L707-V709 HydrophobicContact CG-CG2 3.82Å
708N98.4Very high97.1Very high0 Ų032 Ų320%017%0.172CC..EExtended strand (participates in β ladder)trans-86134.2156.5-78.2-51.1000109.3Q405 N672 T673 Q674 H706 R735 G738Q405-N708 WeakPolarHBondContact CB-OD1 3.45Å; Q405-N708 PolarHBondContact OE1-OD1 3.25Å; N672-N708 PolarHBondContact O-N 3.08Å; T673-N708 HydrophobicContact CG2-CB 3.93Å; T673-N708 PolarHBondContact OG1-ND2 2.84Å; T673-N708 VanDerWaalsContact OG1-ND2 3.15Å; Q674-N708 PolarHBondContact N-O 2.73Å; H706-N708 PolarHBondContact CE1-N 3.47Å; H706-N708 VanDerWaalsContact CE1-N 3.34Å; H706-N708 PolarHBondContact CE1-ND2 3.48Å; H706-N708 VanDerWaalsContact CE1-ND2 3.27Å; H706-N708 PolarHBondContact NE2-ND2 2.67Å; N708-R735 HydrophobicContact CB-CB 3.52Å; N708-R735 HydrophobicContact CB-CG 3.98Å; N708-R735 PolarHBondContact OD1-NE 2.72Å; N708-R735 PolarHBondContact OD1-NH2 3.16Å; N708-G738 VanDerWaalsContact ND2-CA 3.28Å; N708-G738 WeakPolarHBondContact ND2-CA 3.19Å; N708-G738 PolarHBondContact ND2-N 2.98Å
709V97.9Very high97.1Very high6 Ų632.8 Ų32.84%0.03617%0.168CC..EExtended strand (participates in β ladder)trans-115.8119.6-179.8-178.60000109.3Y406 L692 L696 L707 V711Y406-V709 HydrophobicContact CD2-CG2 3.82Å; Y406-V709 HydrophobicContact CE2-CB 4.29Å; Y406-V709 HydrophobicContact CE2-CG2 3.73Å; L692-V709 HydrophobicContact CD1-CG1 3.93Å; L692-V709 HydrophobicContact CD1-CG2 4.44Å; L692-V709 HydrophobicContact CD2-CG1 4.08Å; L696-V709 HydrophobicContact CD2-CG2 4.39Å; L707-V709 HydrophobicContact CD2-CG2 3.78Å; L707-V709 HydrophobicContact CG-CG2 3.82Å; V709-V711 HydrophobicContact CG1-CG2 3.84Å
710N98Very high97Very high2 Ų232.5 Ų32.51%0.01117%0.167CC..EExtended strand (participates in β ladder)trans-113.7128.3169.5-75.5-39.8000109.4Q674 S675 I676 F712 R735Q674-N710 PolarHBondContact O-N 2.74Å; S675-N710 WeakPolarHBondContact CA-O 3.28Å; S675-N710 WeakPolarHBondContact OG-CB 3.3Å; S675-N710 PolarHBondContact OG-ND2 3.44Å; I676-N710 PolarHBondContact N-O 3.32Å; N710-F712 HydrophobicContact CB-CD1 4.24Å; N710-F712 HydrophobicContact CB-CE1 3.48Å; N710-F712 VanDerWaalsContact CB-CE1 3.48Å; N710-F712 HydrophobicContact CB-CE2 4.34Å; N710-F712 HydrophobicContact CB-CZ 3.54Å; N710-F712 VanDerWaalsContact CG-CZ 3.5Å; N710-F712 WeakPolarHBondContact OD1-CE1 3.45Å; N710-R735 PolarHBondContact ND2-O 3.28Å; N710-R735 WeakPolarHBondContact OD1-CB 3.24Å; N710-R735 PolarHBondContact OD1-N 3.02Å
711V97.1Very high96.9Very high9 Ų933.5 Ų33.56%0.05517%0.172CC..EExtended strand (participates in β ladder)trans-122.581.4-179.6-169.90000109.4I399 S402 I676 P678 L681 V709I399-V711 HydrophobicContact CG1-CG1 4.38Å; I399-V711 HydrophobicContact CG1-CG2 4.2Å; I399-V711 HydrophobicContact CG2-CG1 4.32Å; S402-V711 PolarHBondContact OG-N 2.86Å; I676-V711 HydrophobicContact CG2-CG2 4.25Å; I676-V711 WeakPolarHBondContact O-CA 3.47Å; P678-V711 HydrophobicContact CB-CG1 4.38Å; P678-V711 HydrophobicContact CG-CG1 4.17Å; L681-V711 HydrophobicContact CD2-CG1 4.19Å; L681-V711 HydrophobicContact CD2-CG2 4.41Å; V709-V711 HydrophobicContact CG1-CG2 3.84Å
712F95.1Very high96.8Very high6 Ų633.4 Ų33.43%0.02617%0.168CC..  trans-162.5156.217746.9-101.3000111S402 I676 N710 K716 L717 F732 I734 F759S402-F712 WeakPolarHBondContact OG-CD1 3.36Å; I676-F712 PolarHBondContact O-N 2.81Å; N710-F712 HydrophobicContact CB-CD1 4.24Å; N710-F712 HydrophobicContact CB-CE1 3.48Å; N710-F712 VanDerWaalsContact CB-CE1 3.48Å; N710-F712 HydrophobicContact CB-CE2 4.34Å; N710-F712 HydrophobicContact CB-CZ 3.54Å; N710-F712 VanDerWaalsContact CG-CZ 3.5Å; N710-F712 WeakPolarHBondContact OD1-CE1 3.45Å; F712-K716 HydrophobicContact CB-CD 4.3Å; F712-L717 HydrophobicContact CD2-CD2 4.01Å; F712-L717 HydrophobicContact CD2-CG 4.2Å; F712-L717 HydrophobicContact CE2-CD1 3.99Å; F712-L717 HydrophobicContact CE2-CD2 3.67Å; F712-L717 HydrophobicContact CE2-CG 3.94Å; F712-L717 HydrophobicContact CZ-CD2 4.31Å; F712-F732 HydrophobicContact CD1-CE2 4.26Å; F712-F732 HydrophobicContact CD1-CZ 4Å; F712-F732 HydrophobicContact CD2-CZ 4.44Å; F712-F732 HydrophobicContact CE1-CZ 4.25Å; F712-F732 HydrophobicContact CG-CZ 4.1Å; F712-I734 HydrophobicContact CE1-CB 4.25Å; F712-I734 HydrophobicContact CE1-CG2 3.63Å; F712-I734 HydrophobicContact CE2-CG2 4.26Å; F712-I734 HydrophobicContact CZ-CB 3.95Å; F712-I734 HydrophobicContact CZ-CG2 3.41Å; F712-I734 VanDerWaalsContact CZ-CG2 3.41Å; F712-F759 AromaticContact CD2-CE1 3.99Å; F712-F759 HydrophobicContact CD2-CE1 3.99Å; F712-F759 AromaticContact CE2-CE1 3.76Å; F712-F759 HydrophobicContact CE2-CE1 3.76Å; F712-F759 HydrophobicContact CE2-CZ 4.44Å
713G92.6Very high96.7Very high15 Ų1532.7 Ų32.716%0.15517%0.165CC..  trans-80153.7173.700000113.1N677 E715 K716N677-G713 WeakPolarHBondContact OD1-CA 3.17Å; G713-E715 PolarHBondContact O-N 3.27Å; G713-K716 WeakPolarHBondContact O-CB 3.31Å; G713-K716 PolarHBondContact O-N 3.28Å; G713-K716 VanDerWaalsContact O-N 3.15Å
714K94.4Very high96.6Very high76 Ų7634.5 Ų34.533%0.3317%0.172SC..Hα-helixtrans-57.7-32.8176.4-176.9173.1-179.2156.50112.3K716 L717 I718 I755 F759K714-K716 VanDerWaalsContact C-N 3.27Å; K714-K716 PolarHBondContact O-N 3.37Å; K714-L717 WeakPolarHBondContact O-CB 3.48Å; K714-L717 PolarHBondContact O-N 3.09Å; K714-L717 VanDerWaalsContact O-N 3.14Å; K714-I718 HydrophobicContact CG-CD1 4.17Å; K714-I718 PolarHBondContact O-N 3.07Å; K714-I718 VanDerWaalsContact O-N 3.11Å; K714-I755 HydrophobicContact CD-CG2 4.49Å; K714-I755 VanDerWaalsContact CE-CG2 3.41Å; K714-I755 WeakPolarHBondContact CE-O 3.37Å; K714-I755 HydrophobicContact CG-CG2 4.35Å; K714-I755 PolarHBondContact NZ-O 3.13Å; K714-F759 HydrophobicContact CB-CD1 4.37Å; K714-F759 HydrophobicContact CB-CD2 4.17Å; K714-F759 HydrophobicContact CB-CE2 4.37Å; K714-F759 HydrophobicContact CB-CG 4.2Å; K714-F759 HydrophobicContact CD-CD2 4.37Å; K714-F759 HydrophobicContact CG-CD2 4.41Å; K714-F759 HydrophobicContact CG-CE2 4.34Å
715E95.2Very high96.4Very high136 Ų13641.1 Ų41.164%0.63620%0.203SC*.Hα-helixtrans-60.6-36.2179.5-63.370.7-15500111.8G713 L717 I718 D719G713-E715 PolarHBondContact O-N 3.27Å; E715-L717 VanDerWaalsContact C-N 3.33Å; E715-L717 PolarHBondContact O-N 2.95Å; E715-I718 PolarHBondContact O-N 3.45Å; E715-D719 PolarHBondContact O-N 3.35Å
716K95.3Very high96.2Very high88 Ų8844.1 Ų44.138%0.38322%0.216SC..Hα-helixtrans-64.6-38.7177-171.2172.6-176.4175.90111.5F712 G713 K714 A720 Y729 F732F712-K716 HydrophobicContact CB-CD 4.3Å; G713-K716 WeakPolarHBondContact O-CB 3.31Å; G713-K716 PolarHBondContact O-N 3.28Å; G713-K716 VanDerWaalsContact O-N 3.15Å; K714-K716 VanDerWaalsContact C-N 3.27Å; K714-K716 PolarHBondContact O-N 3.37Å; K716-A720 WeakPolarHBondContact O-CB 3.15Å; K716-A720 PolarHBondContact O-N 3.05Å; K716-Y729 HydrophobicContact CG-CE1 4.21Å; K716-F732 HydrophobicContact CD-CE2 3.89Å; K716-F732 HydrophobicContact CD-CZ 3.94Å; K716-F732 VanDerWaalsContact CE-CE2 3.49Å; K716-F732 HydrophobicContact CG-CZ 4.2Å
717L97Very high95.8Very high0 Ų052.8 Ų52.80%026%0.257CS..Hα-helixtrans-67.2-40.8175-59.8-165.9000111.8F712 K714 E715 A720 M721 F732 I734 F743 V754 I755 F759F712-L717 HydrophobicContact CD2-CD2 4.01Å; F712-L717 HydrophobicContact CD2-CG 4.2Å; F712-L717 HydrophobicContact CE2-CD1 3.99Å; F712-L717 HydrophobicContact CE2-CD2 3.67Å; F712-L717 HydrophobicContact CE2-CG 3.94Å; F712-L717 HydrophobicContact CZ-CD2 4.31Å; K714-L717 WeakPolarHBondContact O-CB 3.48Å; K714-L717 PolarHBondContact O-N 3.09Å; K714-L717 VanDerWaalsContact O-N 3.14Å; E715-L717 VanDerWaalsContact C-N 3.33Å; E715-L717 PolarHBondContact O-N 2.95Å; L717-A720 PolarHBondContact O-N 2.95Å; L717-M721 WeakPolarHBondContact O-CB 3.49Å; L717-M721 PolarHBondContact O-N 3.39Å; L717-F732 HydrophobicContact CD2-CE1 3.52Å; L717-F732 HydrophobicContact CD2-CZ 3.93Å; L717-I734 HydrophobicContact CD2-CG2 4.21Å; L717-F743 HydrophobicContact CB-CE1 4.33Å; L717-F743 HydrophobicContact CB-CE2 4.38Å; L717-F743 HydrophobicContact CB-CZ 3.95Å; L717-F743 HydrophobicContact CD1-CE2 4.31Å; L717-F743 HydrophobicContact CD2-CD2 4.19Å; L717-F743 HydrophobicContact CD2-CE2 4.2Å; L717-F743 HydrophobicContact CD2-CG 4.37Å; L717-F743 HydrophobicContact CD2-CZ 4.4Å; L717-F743 WeakPolarHBondContact O-CE1 3.42Å; L717-V754 HydrophobicContact CD1-CG1 3.71Å; L717-I755 HydrophobicContact CB-CD1 4.2Å; L717-I755 HydrophobicContact CB-CG1 3.78Å; L717-I755 HydrophobicContact CD1-CG1 3.96Å; L717-F759 HydrophobicContact CD1-CE1 4.11Å; L717-F759 HydrophobicContact CD1-CZ 3.55Å; L717-F759 HydrophobicContact CG-CZ 4.47Å
718I97Very high95.5Very high72 Ų7258.4 Ų58.437%0.36928%0.283SS..Hα-helixtrans-62.7-45.8177.5-65.6168.3000109.9K714 E715 M721 E722 I755K714-I718 HydrophobicContact CG-CD1 4.17Å; K714-I718 PolarHBondContact O-N 3.07Å; K714-I718 VanDerWaalsContact O-N 3.11Å; E715-I718 PolarHBondContact O-N 3.45Å; I718-M721 PolarHBondContact O-N 2.66Å; I718-E722 WeakPolarHBondContact O-CG 3.37Å; I718-E722 PolarHBondContact O-N 2.51Å; I718-I755 HydrophobicContact CG1-CD1 4.41Å; I718-I755 HydrophobicContact CG1-CG2 4.48Å
719D97.5Very high95.3Very high48 Ų4858.9 Ų58.926%0.25729%0.285SS..Hα-helixtrans-64.8-40.9177.6-173.471.4000112E715 M721 E722 H723 K726 Y729E715-D719 PolarHBondContact O-N 3.35Å; D719-M721 VanDerWaalsContact C-N 3.3Å; D719-M721 PolarHBondContact O-N 2.95Å; D719-E722 PolarHBondContact O-N 3.06Å; D719-H723 WeakPolarHBondContact O-CA 3.46Å; D719-H723 WeakPolarHBondContact O-CB 3.42Å; D719-H723 PolarHBondContact O-N 2.9Å; D719-H723 IonicContact OD1-CD2 3.64Å; D719-H723 PolarHBondContact OD1-CD2 3.29Å; D719-K726 IonicContact OD1-NZ 2.69Å; D719-K726 PolarHBondContact OD1-NZ 3.5Å; D719-K726 IonicContact OD2-NZ 3.72Å; D719-K726 PolarHBondContact OD2-NZ 3.11Å; D719-Y729 WeakPolarHBondContact OD2-CE2 3.2Å; D719-Y729 VanDerWaalsContact OD2-CZ 3.23Å; D719-Y729 PolarHBondContact OD2-OH 3.34Å
720A96.6Very high95Very high0 Ų059.5 Ų59.50%029%0.29CS..Hα-helixtrans-65.6-31.8174.900000113.4K716 L717 P724 Y729 F732 F743K716-A720 WeakPolarHBondContact O-CB 3.15Å; K716-A720 PolarHBondContact O-N 3.05Å; L717-A720 PolarHBondContact O-N 2.95Å; A720-P724 WeakPolarHBondContact O-CA 3.2Å; A720-Y729 VanDerWaalsContact CA-CE2 3.46Å; A720-Y729 HydrophobicContact CB-CD1 3.78Å; A720-Y729 HydrophobicContact CB-CD2 3.77Å; A720-Y729 HydrophobicContact CB-CE1 3.92Å; A720-Y729 HydrophobicContact CB-CE2 3.87Å; A720-Y729 HydrophobicContact CB-CG 3.73Å; A720-F732 HydrophobicContact CB-CD1 4.47Å; A720-F743 HydrophobicContact CB-CD1 3.63Å; A720-F743 HydrophobicContact CB-CE1 3.9Å
721M96.3Very high94.8Very high24 Ų2460.3 Ų60.312%0.11830%0.295CS..Hα-helixtrans-73-34177.6-179.5177.167.100112L717 I718 D719 F743 R748 Q751 E752 I755L717-M721 WeakPolarHBondContact O-CB 3.49Å; L717-M721 PolarHBondContact O-N 3.39Å; I718-M721 PolarHBondContact O-N 2.66Å; D719-M721 VanDerWaalsContact C-N 3.3Å; D719-M721 PolarHBondContact O-N 2.95Å; M721-F743 HydrophobicContact CB-CE1 3.9Å; M721-F743 HydrophobicContact CB-CZ 4.24Å; M721-R748 PolarHBondContact SD-NE 3.34Å; M721-R748 VanDerWaalsContact SD-NE 3.44Å; M721-Q751 HydrophobicContact CG-CB 4.48Å; M721-Q751 HydrophobicContact SD-CB 4.14Å; M721-E752 HydrophobicContact SD-CG 4.38Å; M721-I755 HydrophobicContact CB-CD1 4.39Å; M721-I755 HydrophobicContact CE-CD1 3.69Å; M721-I755 HydrophobicContact SD-CD1 3.54Å; M721-I755 VanDerWaalsContact SD-CD1 3.54Å
722E96.8Very high94.8Very high96 Ų9660.8 Ų60.845%0.44930%0.296SS..Hα-helixtrans-89.1-27.1178.8-63.4-56.2133.800113.3I718 D719 P724 R748I718-E722 WeakPolarHBondContact O-CG 3.37Å; I718-E722 PolarHBondContact O-N 2.51Å; D719-E722 PolarHBondContact O-N 3.06Å; E722-P724 VanDerWaalsContact C-CD 3.4Å; E722-R748 IonicContact OE1-CZ 3.7Å; E722-R748 VanDerWaalsContact OE1-CZ 3.26Å; E722-R748 IonicContact OE1-NH1 3.25Å; E722-R748 PolarHBondContact OE1-NH1 2.9Å; E722-R748 IonicContact OE1-NH2 3.51Å; E722-R748 PolarHBondContact OE1-NH2 3.27Å
723H96Very high94.9Very high76 Ų7660.5 Ų60.535%0.35230%0.295SS..  trans-127.755.5-176.9-61.1-65.4000113.2D719 E725 K726 Y729D719-H723 WeakPolarHBondContact O-CA 3.46Å; D719-H723 WeakPolarHBondContact O-CB 3.42Å; D719-H723 PolarHBondContact O-N 2.9Å; D719-H723 IonicContact OD1-CD2 3.64Å; D719-H723 PolarHBondContact OD1-CD2 3.29Å; H723-E725 VanDerWaalsContact CA-OE2 3.26Å; H723-E725 WeakPolarHBondContact CA-OE2 3.46Å; H723-E725 IonicContact CG-OE1 3.64Å; H723-E725 IonicContact ND1-OE1 3.47Å; H723-E725 PolarHBondContact ND1-OE1 2.85Å; H723-E725 PolarHBondContact O-N 2.92Å; H723-K726 HydrophobicContact CB-CD 4.04Å; H723-K726 HydrophobicContact CB-CG 4.07Å; H723-K726 PolarHBondContact O-N 3.18Å; H723-Y729 WeakPolarHBondContact O-CD2 3.5Å
724P94Very high95.1Very high61 Ų6159.8 Ų59.840%0.39629%0.287SS..THydrogen-bonded Turntrans-64.1-14.4-177.129.4-37.1000113.7A720 E722 K726 I744A720-P724 WeakPolarHBondContact O-CA 3.2Å; E722-P724 VanDerWaalsContact C-CD 3.4Å; P724-K726 VanDerWaalsContact C-N 3.3Å; P724-K726 PolarHBondContact O-N 3.26Å; P724-I744 HydrophobicContact CB-CB 4.37Å; P724-I744 HydrophobicContact CB-CG2 3.88Å
725E93.2Very high95.2Very high140 Ų14056.1 Ų56.165%0.65427%0.272SS*.THydrogen-bonded Turntrans-73.3-16177.474-74.5175.900114.5H723 E727H723-E725 VanDerWaalsContact CA-OE2 3.26Å; H723-E725 WeakPolarHBondContact CA-OE2 3.46Å; H723-E725 IonicContact CG-OE1 3.64Å; H723-E725 IonicContact ND1-OE1 3.47Å; H723-E725 PolarHBondContact ND1-OE1 2.85Å; H723-E725 PolarHBondContact O-N 2.92Å; E725-E727 PolarHBondContact O-N 3.15Å
726K94.4Very high95.2Very high68 Ų6849.9 Ų49.930%0.29624%0.243SC..SBendtrans-65.6135179.6-66.1-177.5-171.4169.60110.4D719 H723 P724 E728 Y729D719-K726 IonicContact OD1-NZ 2.69Å; D719-K726 PolarHBondContact OD1-NZ 3.5Å; D719-K726 IonicContact OD2-NZ 3.72Å; D719-K726 PolarHBondContact OD2-NZ 3.11Å; H723-K726 HydrophobicContact CB-CD 4.04Å; H723-K726 HydrophobicContact CB-CG 4.07Å; H723-K726 PolarHBondContact O-N 3.18Å; P724-K726 VanDerWaalsContact C-N 3.3Å; P724-K726 PolarHBondContact O-N 3.26Å; K726-E728 VanDerWaalsContact C-N 3.26Å; K726-E728 HydrophobicContact CB-CG 4.1Å; K726-E728 PolarHBondContact O-N 2.99Å; K726-Y729 HydrophobicContact CB-CD2 3.78Å; K726-Y729 HydrophobicContact CB-CE2 4.18Å; K726-Y729 HydrophobicContact CD-CD2 4.22Å; K726-Y729 HydrophobicContact CD-CE2 3.77Å; K726-Y729 HydrophobicContact CG-CD2 4.43Å; K726-Y729 HydrophobicContact CG-CE2 4.45Å; K726-Y729 PolarHBondContact O-N 3.26Å
727E90Very high95Very high181 Ų18145.8 Ų45.885%0.84623%0.225SC*.G310 helixtrans-60-35.6-176.2-172.9169.2-167.600112.8E725 Y729 A730E725-E727 PolarHBondContact O-N 3.15Å; E727-Y729 PolarHBondContact O-N 3.14Å; E727-Y729 VanDerWaalsContact O-N 3.15Å; E727-A730 VanDerWaalsContact O-CB 3.31Å; E727-A730 WeakPolarHBondContact O-CB 3.28Å; E727-A730 PolarHBondContact O-N 2.92Å; E727-A730 VanDerWaalsContact O-N 3.12Å
728E92.2Very high94.4Very high123 Ų12345.8 Ų45.858%0.57523%0.225SC*.G310 helixtrans-59.9-23.9175.966.7-178144.100113.7K726K726-E728 VanDerWaalsContact C-N 3.26Å; K726-E728 HydrophobicContact CB-CG 4.1Å; K726-E728 PolarHBondContact O-N 2.99Å
729Y94.7Very high94.2Very high9 Ų942.3 Ų42.34%0.03521%0.207CC..G310 helixtrans-94.5-8.9180-59.2-39.5000114.1K716 D719 A720 H723 K726 E727 N731 F732K716-Y729 HydrophobicContact CG-CE1 4.21Å; D719-Y729 WeakPolarHBondContact OD2-CE2 3.2Å; D719-Y729 VanDerWaalsContact OD2-CZ 3.23Å; D719-Y729 PolarHBondContact OD2-OH 3.34Å; A720-Y729 VanDerWaalsContact CA-CE2 3.46Å; A720-Y729 HydrophobicContact CB-CD1 3.78Å; A720-Y729 HydrophobicContact CB-CD2 3.77Å; A720-Y729 HydrophobicContact CB-CE1 3.92Å; A720-Y729 HydrophobicContact CB-CE2 3.87Å; A720-Y729 HydrophobicContact CB-CG 3.73Å; H723-Y729 WeakPolarHBondContact O-CD2 3.5Å; K726-Y729 HydrophobicContact CB-CD2 3.78Å; K726-Y729 HydrophobicContact CB-CE2 4.18Å; K726-Y729 HydrophobicContact CD-CD2 4.22Å; K726-Y729 HydrophobicContact CD-CE2 3.77Å; K726-Y729 HydrophobicContact CG-CD2 4.43Å; K726-Y729 HydrophobicContact CG-CE2 4.45Å; K726-Y729 PolarHBondContact O-N 3.26Å; E727-Y729 PolarHBondContact O-N 3.14Å; E727-Y729 VanDerWaalsContact O-N 3.15Å; Y729-N731 PolarHBondContact O-N 3.48Å; Y729-N731 VanDerWaalsContact O-N 3.12Å; Y729-F732 HydrophobicContact CD1-CB 3.97Å; Y729-F732 HydrophobicContact CD1-CD1 4.28Å; Y729-F732 HydrophobicContact CD1-CG 4.19Å; Y729-F732 PolarHBondContact O-N 3.35Å
730A92Very high94.2Very high19 Ų1940.1 Ų40.116%0.15720%0.196CC..THydrogen-bonded Turntrans-58.6-29.6179.800000113.3E727 K742E727-A730 VanDerWaalsContact O-CB 3.31Å; E727-A730 WeakPolarHBondContact O-CB 3.28Å; E727-A730 PolarHBondContact O-N 2.92Å; E727-A730 VanDerWaalsContact O-N 3.12Å; A730-K742 WeakPolarHBondContact O-CD 3.13Å; A730-K742 PolarHBondContact O-NZ 3.47Å
731N93.4Very high94.1Very high19 Ų1940.1 Ų40.110%0.10220%0.196CC..THydrogen-bonded Turntrans-123.78.7177.5-76.8-19.8000112.6Q66 Y729 T733 K742Q66-N731 PolarHBondContact NE2-ND2 3.44Å; Y729-N731 PolarHBondContact O-N 3.48Å; Y729-N731 VanDerWaalsContact O-N 3.12Å; N731-T733 PolarHBondContact O-N 3.15Å; N731-T733 PolarHBondContact O-OG1 2.71Å; N731-K742 VanDerWaalsContact OD1-CE 3.32Å; N731-K742 WeakPolarHBondContact OD1-CE 3.12Å; N731-K742 PolarHBondContact OD1-NZ 3.49Å
732F96.3Very high94.1Very high19 Ų1939.6 Ų39.68%0.08319%0.193CC..  trans-63.7112.5179.8177-116.5000109.9F712 K716 L717 A720 Y729 I734 K742 F743F712-F732 HydrophobicContact CD1-CE2 4.26Å; F712-F732 HydrophobicContact CD1-CZ 4Å; F712-F732 HydrophobicContact CD2-CZ 4.44Å; F712-F732 HydrophobicContact CE1-CZ 4.25Å; F712-F732 HydrophobicContact CG-CZ 4.1Å; K716-F732 HydrophobicContact CD-CE2 3.89Å; K716-F732 HydrophobicContact CD-CZ 3.94Å; K716-F732 VanDerWaalsContact CE-CE2 3.49Å; K716-F732 HydrophobicContact CG-CZ 4.2Å; L717-F732 HydrophobicContact CD2-CE1 3.52Å; L717-F732 HydrophobicContact CD2-CZ 3.93Å; A720-F732 HydrophobicContact CB-CD1 4.47Å; Y729-F732 HydrophobicContact CD1-CB 3.97Å; Y729-F732 HydrophobicContact CD1-CD1 4.28Å; Y729-F732 HydrophobicContact CD1-CG 4.19Å; Y729-F732 PolarHBondContact O-N 3.35Å; F732-I734 HydrophobicContact CD1-CG2 4.47Å; F732-I734 HydrophobicContact CE1-CG2 3.78Å; F732-I734 HydrophobicContact CZ-CG2 3.83Å; F732-K742 WeakPolarHBondContact O-CA 3.44Å; F732-F743 HydrophobicContact CD1-CB 3.9Å; F732-F743 HydrophobicContact CE1-CB 4.22Å; F732-F743 PolarHBondContact O-N 3.04Å
733T97.6Very high94.1Very high0 Ų035 Ų350%017%0.172CC..EExtended strand (participates in β ladder)trans-109.9140.3-167.5-63.90000109.5P374 S403 N731 A740 V741P374-T733 HydrophobicContact CB-CG2 4.26Å; S403-T733 WeakPolarHBondContact OG-CB 3.45Å; S403-T733 WeakPolarHBondContact OG-CG2 3.37Å; N731-T733 PolarHBondContact O-N 3.15Å; N731-T733 PolarHBondContact O-OG1 2.71Å; T733-A740 HydrophobicContact CG2-CB 3.65Å; T733-V741 WeakPolarHBondContact CA-O 3.15Å
734I97.5Very high93.9Very high0 Ų032.7 Ų32.70%016%0.162CC..EExtended strand (participates in β ladder)trans-133.2146.7178.761.7157.4000110.3F712 L717 F732 V736 A740 V741 F743 L746 V754F712-I734 HydrophobicContact CE1-CB 4.25Å; F712-I734 HydrophobicContact CE1-CG2 3.63Å; F712-I734 HydrophobicContact CE2-CG2 4.26Å; F712-I734 HydrophobicContact CZ-CB 3.95Å; F712-I734 HydrophobicContact CZ-CG2 3.41Å; F712-I734 VanDerWaalsContact CZ-CG2 3.41Å; L717-I734 HydrophobicContact CD2-CG2 4.21Å; F732-I734 HydrophobicContact CD1-CG2 4.47Å; F732-I734 HydrophobicContact CE1-CG2 3.78Å; F732-I734 HydrophobicContact CZ-CG2 3.83Å; I734-V736 HydrophobicContact CD1-CG1 3.59Å; I734-V736 HydrophobicContact CG1-CG1 3.95Å; I734-A740 CarbonylContact O-C 3.55Å; I734-A740 WeakPolarHBondContact O-CA 3.46Å; I734-V741 HydrophobicContact CD1-CG2 4.24Å; I734-V741 HydrophobicContact CG1-CG2 3.75Å; I734-V741 PolarHBondContact N-O 2.59Å; I734-V741 PolarHBondContact O-N 3.16Å; I734-F743 HydrophobicContact CD1-CB 4.49Å; I734-F743 HydrophobicContact CD1-CD2 3.62Å; I734-F743 HydrophobicContact CD1-CE2 4.39Å; I734-F743 HydrophobicContact CG1-CB 4.37Å; I734-F743 HydrophobicContact CG1-CD2 4.38Å; I734-F743 HydrophobicContact CG2-CB 4.41Å; I734-L746 HydrophobicContact CD1-CD1 4.23Å; I734-V754 HydrophobicContact CD1-CB 4.39Å; I734-V754 HydrophobicContact CD1-CG1 3.63Å; I734-V754 HydrophobicContact CD1-CG2 4.05Å
735R97.2Very high93.8Very high0 Ų032.6 Ų32.60%016%0.158CC..EExtended strand (participates in β ladder)trans-82.4134.7168.7-49.9-57.6-63.5176.45.4110.2N377 S402 S403 I404 Q405 T673 N708 N710 Y739 A740N377-R735 VanDerWaalsContact OD1-CZ 3.26Å; N377-R735 PolarHBondContact OD1-NH1 2.91Å; N377-R735 PolarHBondContact OD1-NH2 2.79Å; S402-R735 VanDerWaalsContact O-CD 3.23Å; S402-R735 WeakPolarHBondContact O-CD 3.06Å; S402-R735 VanDerWaalsContact O-CG 3.26Å; S402-R735 WeakPolarHBondContact O-CG 3.45Å; S403-R735 PolarHBondContact O-NH1 3Å; I404-R735 WeakPolarHBondContact O-CD 3.14Å; I404-R735 PolarHBondContact O-NE 3.05Å; Q405-R735 VanDerWaalsContact CG-NH2 3.34Å; T673-R735 WeakPolarHBondContact CG2-O 3.42Å; N708-R735 HydrophobicContact CB-CB 3.52Å; N708-R735 HydrophobicContact CB-CG 3.98Å; N708-R735 PolarHBondContact OD1-NE 2.72Å; N708-R735 PolarHBondContact OD1-NH2 3.16Å; N710-R735 PolarHBondContact ND2-O 3.28Å; N710-R735 WeakPolarHBondContact OD1-CB 3.24Å; N710-R735 PolarHBondContact OD1-N 3.02Å; R735-Y739 VanDerWaalsContact NH2-CA 3.34Å; R735-A740 VanDerWaalsContact NH1-CB 3.3Å
736V93.6Very high93.8Very high5 Ų526.5 Ų26.53%0.0313%0.129CC..  trans-124-41.1-173.9-69.10000115.4I734 Y739 V741 V754 R757I734-V736 HydrophobicContact CD1-CG1 3.59Å; I734-V736 HydrophobicContact CG1-CG1 3.95Å; V736-Y739 HydrophobicContact CG2-CD1 3.98Å; V736-Y739 HydrophobicContact CG2-CD2 4.45Å; V736-Y739 HydrophobicContact CG2-CE1 3.52Å; V736-Y739 HydrophobicContact CG2-CE2 4.07Å; V736-Y739 HydrophobicContact CG2-CG 4.41Å; V736-Y739 PolarHBondContact N-O 3.41Å; V736-V741 HydrophobicContact CG1-CG2 3.68Å; V736-V741 HydrophobicContact CG2-CG1 4.06Å; V736-V741 HydrophobicContact CG2-CG2 4.14Å; V736-V754 HydrophobicContact CG1-CG2 4.03Å; V736-R757 PolarHBondContact O-NH1 2.79Å
737S90.7Very high93.6Very high1 Ų126.7 Ų26.71%0.00714%0.137CC..SBendtrans-16853.4-178.1-165.80000111.6L611 T612 I613L611-S737 WeakPolarHBondContact CD1-O 3.19Å; T612-S737 PolarHBondContact OG1-OG 3.13Å; I613-S737 WeakPolarHBondContact CA-OG 3.41Å; I613-S737 WeakPolarHBondContact CD1-O 3.38Å; I613-S737 PolarHBondContact N-OG 3.38Å; I613-S737 VanDerWaalsContact N-OG 3.14Å; I613-S737 PolarHBondContact O-OG 2.92Å
738G86.4Confident93.6Very high0 Ų023.4 Ų23.40%012%0.116CC..SBendtrans88.911.3-175.100000113.9N377 Q405 C425 S671 N708N377-G738 PolarHBondContact ND2-O 3.24Å; Q405-G738 PolarHBondContact OE1-O 3.44Å; C425-G738 VanDerWaalsContact CA-O 3.3Å; C425-G738 WeakPolarHBondContact CA-O 3.19Å; C425-G738 VanDerWaalsContact CB-O 3.3Å; C425-G738 WeakPolarHBondContact CB-O 3.41Å; C425-G738 PolarHBondContact SG-O 2.83Å; S671-G738 PolarHBondContact OG-N 2.66Å; N708-G738 VanDerWaalsContact ND2-CA 3.28Å; N708-G738 WeakPolarHBondContact ND2-CA 3.19Å; N708-G738 PolarHBondContact ND2-N 2.98Å
739Y92.8Very high93.5Very high0 Ų021.8 Ų21.80%011%0.109CC..SBendtrans-154.8167.9173.574-69.5000109S335 P338 W340 I613 R735 V736 V741S335-Y739 WeakPolarHBondContact O-CE2 3.46Å; S335-Y739 PolarHBondContact O-OH 2.89Å; S335-Y739 PolarHBondContact OG-OH 2.56Å; P338-Y739 HydrophobicContact CB-CD2 3.78Å; P338-Y739 HydrophobicContact CB-CE2 3.6Å; P338-Y739 HydrophobicContact CG-CE2 4.02Å; W340-Y739 HydrophobicContact CZ2-CD1 4.42Å; W340-Y739 HydrophobicContact CZ2-CE1 4.46Å; W340-Y739 HydrophobicContact CZ2-CG 4.48Å; W340-Y739 VanDerWaalsContact NE1-CB 3.33Å; W340-Y739 AromaticContact NE1-CD1 3.72Å; W340-Y739 AromaticContact NE1-CG 3.43Å; I613-Y739 HydrophobicContact CB-CE1 4.31Å; I613-Y739 HydrophobicContact CD1-CD1 3.76Å; I613-Y739 HydrophobicContact CD1-CE1 3.85Å; I613-Y739 HydrophobicContact CG2-CD1 4.39Å; I613-Y739 HydrophobicContact CG2-CE1 3.44Å; I613-Y739 VanDerWaalsContact CG2-CE1 3.44Å; R735-Y739 VanDerWaalsContact NH2-CA 3.34Å; V736-Y739 HydrophobicContact CG2-CD1 3.98Å; V736-Y739 HydrophobicContact CG2-CD2 4.45Å; V736-Y739 HydrophobicContact CG2-CE1 3.52Å; V736-Y739 HydrophobicContact CG2-CE2 4.07Å; V736-Y739 HydrophobicContact CG2-CG 4.41Å; V736-Y739 PolarHBondContact N-O 3.41Å; Y739-V741 HydrophobicContact CD2-CG1 3.91Å; Y739-V741 HydrophobicContact CE2-CG1 3.25Å
740A96.3Very high93.2Very high2 Ų222.1 Ų22.12%0.01711%0.111CC..EExtended strand (participates in β ladder)trans-103.9156.7177.200000111.8P374 T733 I734 R735P374-A740 VanDerWaalsContact CB-C 3.4Å; P374-A740 HydrophobicContact CB-CB 3.79Å; P374-A740 WeakPolarHBondContact CB-O 3Å; T733-A740 HydrophobicContact CG2-CB 3.65Å; I734-A740 CarbonylContact O-C 3.55Å; I734-A740 WeakPolarHBondContact O-CA 3.46Å; R735-A740 VanDerWaalsContact NH1-CB 3.3Å
741V95.7Very high93.3Very high0 Ų022 Ų220%011%0.107CC..EExtended strand (participates in β ladder)trans-140.9154.1171.9-63.80000109.4S335 T733 I734 V736 Y739 F743 L746S335-V741 WeakPolarHBondContact O-CG1 3.43Å; T733-V741 WeakPolarHBondContact CA-O 3.15Å; I734-V741 HydrophobicContact CD1-CG2 4.24Å; I734-V741 HydrophobicContact CG1-CG2 3.75Å; I734-V741 PolarHBondContact N-O 2.59Å; I734-V741 PolarHBondContact O-N 3.16Å; V736-V741 HydrophobicContact CG1-CG2 3.68Å; V736-V741 HydrophobicContact CG2-CG1 4.06Å; V736-V741 HydrophobicContact CG2-CG2 4.14Å; Y739-V741 HydrophobicContact CD2-CG1 3.91Å; Y739-V741 HydrophobicContact CE2-CG1 3.25Å; V741-F743 PolarHBondContact O-N 3.26Å; V741-L746 HydrophobicContact CB-CD2 4.38Å; V741-L746 HydrophobicContact CG1-CD2 4.45Å; V741-L746 HydrophobicContact CG2-CD1 3.92Å; V741-L746 HydrophobicContact CG2-CD2 3.96Å; V741-L746 HydrophobicContact CG2-CG 3.95Å
742K95.4Very high93.3Very high12 Ų1225.8 Ų25.85%0.05212%0.124CC..EExtended strand (participates in β ladder)trans-70129.4160.7-63.9-179.8178.8-167.20107.9Q69 P374 A730 N731 F732 I744 D745Q69-K742 VanDerWaalsContact OE1-NZ 3.09Å; P374-K742 HydrophobicContact CG-CG 4.17Å; A730-K742 WeakPolarHBondContact O-CD 3.13Å; A730-K742 PolarHBondContact O-NZ 3.47Å; N731-K742 VanDerWaalsContact OD1-CE 3.32Å; N731-K742 WeakPolarHBondContact OD1-CE 3.12Å; N731-K742 PolarHBondContact OD1-NZ 3.49Å; F732-K742 WeakPolarHBondContact O-CA 3.44Å; K742-I744 HydrophobicContact CB-CG1 4.46Å; K742-I744 PolarHBondContact O-N 3.47Å; K742-D745 HydrophobicContact CB-CB 4.19Å; K742-D745 WeakPolarHBondContact CB-OD2 3.23Å; K742-D745 WeakPolarHBondContact CD-OD2 3.31Å; K742-D745 PolarHBondContact O-N 3.32Å
743F96.1Very high93Very high0 Ų025.3 Ų25.30%012%0.122CC..G310 helixtrans-61.4-34.6-175.3-178.8-109.5000112.5L717 A720 M721 F732 I734 V741 D745 L746 Q751 V754 I755L717-F743 HydrophobicContact CB-CE1 4.33Å; L717-F743 HydrophobicContact CB-CE2 4.38Å; L717-F743 HydrophobicContact CB-CZ 3.95Å; L717-F743 HydrophobicContact CD1-CE2 4.31Å; L717-F743 HydrophobicContact CD2-CD2 4.19Å; L717-F743 HydrophobicContact CD2-CE2 4.2Å; L717-F743 HydrophobicContact CD2-CG 4.37Å; L717-F743 HydrophobicContact CD2-CZ 4.4Å; L717-F743 WeakPolarHBondContact O-CE1 3.42Å; A720-F743 HydrophobicContact CB-CD1 3.63Å; A720-F743 HydrophobicContact CB-CE1 3.9Å; M721-F743 HydrophobicContact CB-CE1 3.9Å; M721-F743 HydrophobicContact CB-CZ 4.24Å; F732-F743 HydrophobicContact CD1-CB 3.9Å; F732-F743 HydrophobicContact CE1-CB 4.22Å; F732-F743 PolarHBondContact O-N 3.04Å; I734-F743 HydrophobicContact CD1-CB 4.49Å; I734-F743 HydrophobicContact CD1-CD2 3.62Å; I734-F743 HydrophobicContact CD1-CE2 4.39Å; I734-F743 HydrophobicContact CG1-CB 4.37Å; I734-F743 HydrophobicContact CG1-CD2 4.38Å; I734-F743 HydrophobicContact CG2-CB 4.41Å; V741-F743 PolarHBondContact O-N 3.26Å; F743-D745 VanDerWaalsContact C-N 3.25Å; F743-D745 PolarHBondContact O-N 3.37Å; F743-L746 HydrophobicContact CD2-CD1 4.23Å; F743-L746 WeakPolarHBondContact O-CB 3.34Å; F743-L746 PolarHBondContact O-N 2.82Å; F743-Q751 HydrophobicContact CD2-CG 4.32Å; F743-Q751 HydrophobicContact CE1-CG 4.15Å; F743-Q751 HydrophobicContact CE2-CB 3.89Å; F743-Q751 HydrophobicContact CE2-CG 3.77Å; F743-Q751 HydrophobicContact CZ-CB 3.68Å; F743-Q751 HydrophobicContact CZ-CG 3.67Å; F743-Q751 PolarHBondContact O-NE2 3Å; F743-V754 HydrophobicContact CE2-CB 4.44Å; F743-V754 HydrophobicContact CE2-CG1 4.41Å; F743-I755 HydrophobicContact CZ-CD1 4.11Å; F743-I755 HydrophobicContact CZ-CG1 4.35Å
744I93.4Very high92.8Very high28 Ų2825.6 Ų25.614%0.14412%0.124CC..G310 helixtrans-73.2-15178.764.5167.3000113.8P724 K742 L746P724-I744 HydrophobicContact CB-CB 4.37Å; P724-I744 HydrophobicContact CB-CG2 3.88Å; K742-I744 HydrophobicContact CB-CG1 4.46Å; K742-I744 PolarHBondContact O-N 3.47Å; I744-L746 VanDerWaalsContact C-N 3.29Å
745D91.8Very high92.7Very high59 Ų5926.4 Ų26.432%0.31613%0.128SC..G310 helixtrans-85.8-6.7177.2-67.2-10.7000111.8K742 F743K742-D745 HydrophobicContact CB-CB 4.19Å; K742-D745 WeakPolarHBondContact CB-OD2 3.23Å; K742-D745 WeakPolarHBondContact CD-OD2 3.31Å; K742-D745 PolarHBondContact O-N 3.32Å; F743-D745 VanDerWaalsContact C-N 3.25Å; F743-D745 PolarHBondContact O-N 3.37Å
746L91.7Very high92.5Very high11 Ų1129.1 Ų29.16%0.05815%0.147CC..SBendtrans-80149172.3-64.8-178.8000111.1I734 V741 F743 I744 Q750 Q751 V754I734-L746 HydrophobicContact CD1-CD1 4.23Å; V741-L746 HydrophobicContact CB-CD2 4.38Å; V741-L746 HydrophobicContact CG1-CD2 4.45Å; V741-L746 HydrophobicContact CG2-CD1 3.92Å; V741-L746 HydrophobicContact CG2-CD2 3.96Å; V741-L746 HydrophobicContact CG2-CG 3.95Å; F743-L746 HydrophobicContact CD2-CD1 4.23Å; F743-L746 WeakPolarHBondContact O-CB 3.34Å; F743-L746 PolarHBondContact O-N 2.82Å; I744-L746 VanDerWaalsContact C-N 3.29Å; L746-Q750 HydrophobicContact CB-CB 3.96Å; L746-Q750 HydrophobicContact CD1-CB 4.5Å; L746-Q750 HydrophobicContact CD2-CB 4.22Å; L746-Q750 HydrophobicContact CG-CB 4.47Å; L746-Q751 HydrophobicContact CB-CG 3.73Å; L746-V754 HydrophobicContact CD1-CG2 4.06Å
747T89.9Confident92.5Very high73 Ų7330 Ų3045%0.44815%0.15SC..  trans-68.7158.7169.270.60000110.6E749 Q750 Q751T747-E749 PolarHBondContact O-N 3.02Å; T747-E749 VanDerWaalsContact O-N 3.16Å; T747-Q750 CarbonylContact O-C 3.5Å; T747-Q750 WeakPolarHBondContact O-CA 3.3Å; T747-Q750 WeakPolarHBondContact O-CB 3.45Å; T747-Q750 PolarHBondContact O-N 2.91Å; T747-Q750 VanDerWaalsContact OG1-CD 3.3Å; T747-Q750 WeakPolarHBondContact OG1-CG 3.29Å; T747-Q750 PolarHBondContact OG1-N 3.39Å; T747-Q750 PolarHBondContact OG1-OE1 2.78Å; T747-Q751 WeakPolarHBondContact O-CG 3.33Å; T747-Q751 PolarHBondContact O-N 3.37Å
748R91.6Very high92.6Very high111 Ų11131.4 Ų31.442%0.41916%0.159SC..Hα-helixtrans-50.8-42.5177.3-175.765.6175.8-148.14.6112.9M721 E722 Q751 E752M721-R748 PolarHBondContact SD-NE 3.34Å; M721-R748 VanDerWaalsContact SD-NE 3.44Å; E722-R748 IonicContact OE1-CZ 3.7Å; E722-R748 VanDerWaalsContact OE1-CZ 3.26Å; E722-R748 IonicContact OE1-NH1 3.25Å; E722-R748 PolarHBondContact OE1-NH1 2.9Å; E722-R748 IonicContact OE1-NH2 3.51Å; E722-R748 PolarHBondContact OE1-NH2 3.27Å; R748-Q751 WeakPolarHBondContact O-CB 3.43Å; R748-Q751 PolarHBondContact O-N 3.16Å; R748-E752 IonicContact NE-OE1 2.82Å; R748-E752 PolarHBondContact NE-OE1 3.2Å; R748-E752 WeakPolarHBondContact O-CB 3.43Å; R748-E752 VanDerWaalsContact O-CG 3.31Å; R748-E752 WeakPolarHBondContact O-CG 3.35Å; R748-E752 PolarHBondContact O-N 3.43Å
749E88.4Confident93Very high89 Ų8932.8 Ų32.842%0.41617%0.165SC..Hα-helixtrans-65.3-40.5177.3177.6178.3-138.200112.8K621 T747 Q751 E752 D753K621-E749 VanDerWaalsContact CE-CD 3.42Å; K621-E749 WeakPolarHBondContact CE-OE1 3.5Å; K621-E749 IonicContact NZ-OE1 3.27Å; K621-E749 PolarHBondContact NZ-OE1 3.35Å; K621-E749 IonicContact NZ-OE2 2.92Å; K621-E749 PolarHBondContact NZ-OE2 3.09Å; T747-E749 PolarHBondContact O-N 3.02Å; T747-E749 VanDerWaalsContact O-N 3.16Å; E749-Q751 VanDerWaalsContact C-N 3.33Å; E749-E752 PolarHBondContact O-N 3.33Å; E749-D753 PolarHBondContact O-N 3.14Å
750Q89.9Confident93.2Very high17 Ų1733.2 Ų33.28%0.07917%0.166CC..Hα-helixtrans-69.4-34176-69.5162.4-600111.4S335 T614 L746 T747 D753 V754S335-Q750 VanDerWaalsContact CB-NE2 3.29Å; S335-Q750 VanDerWaalsContact CB-OE1 3.29Å; T614-Q750 HydrophobicContact CG2-CG 4.27Å; L746-Q750 HydrophobicContact CB-CB 3.96Å; L746-Q750 HydrophobicContact CD1-CB 4.5Å; L746-Q750 HydrophobicContact CD2-CB 4.22Å; L746-Q750 HydrophobicContact CG-CB 4.47Å; T747-Q750 CarbonylContact O-C 3.5Å; T747-Q750 WeakPolarHBondContact O-CA 3.3Å; T747-Q750 WeakPolarHBondContact O-CB 3.45Å; T747-Q750 PolarHBondContact O-N 2.91Å; T747-Q750 VanDerWaalsContact OG1-CD 3.3Å; T747-Q750 WeakPolarHBondContact OG1-CG 3.29Å; T747-Q750 PolarHBondContact OG1-N 3.39Å; T747-Q750 PolarHBondContact OG1-OE1 2.78Å; Q750-D753 WeakPolarHBondContact O-CB 3.22Å; Q750-D753 PolarHBondContact O-N 3.25Å; Q750-V754 WeakPolarHBondContact O-CG2 3.1Å; Q750-V754 PolarHBondContact O-N 2.97Å; Q750-V754 VanDerWaalsContact O-N 3.11Å
751Q94Very high93Very high15 Ų1536.8 Ų36.87%0.0720%0.196CC..Hα-helixtrans-65-43.9172.1-68.2173.7-26.200111M721 F743 L746 T747 R748 E749 D753 V754 I755M721-Q751 HydrophobicContact CG-CB 4.48Å; M721-Q751 HydrophobicContact SD-CB 4.14Å; F743-Q751 HydrophobicContact CD2-CG 4.32Å; F743-Q751 HydrophobicContact CE1-CG 4.15Å; F743-Q751 HydrophobicContact CE2-CB 3.89Å; F743-Q751 HydrophobicContact CE2-CG 3.77Å; F743-Q751 HydrophobicContact CZ-CB 3.68Å; F743-Q751 HydrophobicContact CZ-CG 3.67Å; F743-Q751 PolarHBondContact O-NE2 3Å; L746-Q751 HydrophobicContact CB-CG 3.73Å; T747-Q751 WeakPolarHBondContact O-CG 3.33Å; T747-Q751 PolarHBondContact O-N 3.37Å; R748-Q751 WeakPolarHBondContact O-CB 3.43Å; R748-Q751 PolarHBondContact O-N 3.16Å; E749-Q751 VanDerWaalsContact C-N 3.33Å; Q751-D753 VanDerWaalsContact C-N 3.34Å; Q751-D753 PolarHBondContact O-N 2.9Å; Q751-V754 PolarHBondContact O-N 2.66Å; Q751-I755 WeakPolarHBondContact O-CB 3.36Å; Q751-I755 VanDerWaalsContact O-CG1 3.26Å; Q751-I755 WeakPolarHBondContact O-CG1 3.37Å; Q751-I755 PolarHBondContact O-N 2.8Å
752E93Very high92.9Very high100 Ų10042.2 Ų42.247%0.46722%0.22SC..Hα-helixtrans-62.2-39.3175.8-74.8169.7179.900111.9M721 R748 E749 I755 S756M721-E752 HydrophobicContact SD-CG 4.38Å; R748-E752 IonicContact NE-OE1 2.82Å; R748-E752 PolarHBondContact NE-OE1 3.2Å; R748-E752 WeakPolarHBondContact O-CB 3.43Å; R748-E752 VanDerWaalsContact O-CG 3.31Å; R748-E752 WeakPolarHBondContact O-CG 3.35Å; R748-E752 PolarHBondContact O-N 3.43Å; E749-E752 PolarHBondContact O-N 3.33Å; E752-I755 PolarHBondContact O-N 2.92Å; E752-S756 WeakPolarHBondContact O-CB 3.44Å; E752-S756 PolarHBondContact O-N 3.46Å; E752-S756 PolarHBondContact O-OG 3.11Å
753D90.8Very high92.6Very high8 Ų845.4 Ų45.44%0.04324%0.236CC..Hα-helixtrans-54.4-55.2169.5171.947.1000110.8N616 V617 P635 Y644 E749 Q750 Q751 I755 S756 R757N616-D753 PolarHBondContact ND2-OD2 3.47Å; V617-D753 HydrophobicContact CG2-CB 4.18Å; P635-D753 HydrophobicContact CG-CB 4.48Å; Y644-D753 WeakPolarHBondContact CE1-OD1 3.43Å; Y644-D753 VanDerWaalsContact CZ-OD1 3.27Å; Y644-D753 PolarHBondContact OH-OD1 2.78Å; E749-D753 PolarHBondContact O-N 3.14Å; Q750-D753 WeakPolarHBondContact O-CB 3.22Å; Q750-D753 PolarHBondContact O-N 3.25Å; Q751-D753 VanDerWaalsContact C-N 3.34Å; Q751-D753 PolarHBondContact O-N 2.9Å; D753-I755 VanDerWaalsContact C-N 3.34Å; D753-I755 PolarHBondContact O-N 3.01Å; D753-S756 PolarHBondContact O-N 3.45Å; D753-S756 VanDerWaalsContact O-N 3.1Å; D753-S756 PolarHBondContact O-OG 2.91Å; D753-R757 PolarHBondContact O-N 3.41Å; D753-R757 IonicContact OD2-CZ 3.32Å; D753-R757 IonicContact OD2-NE 2.74Å; D753-R757 IonicContact OD2-NH2 2.86Å; D753-R757 PolarHBondContact OD2-NH2 3.23Å
754V93.5Very high92.4Very high6 Ų647.7 Ų47.74%0.03625%0.248CC..Hα-helixtrans-59.1-43.9-179.3174.70000111.9L717 I734 V736 F743 L746 Q750 Q751 S756 R757L717-V754 HydrophobicContact CD1-CG1 3.71Å; I734-V754 HydrophobicContact CD1-CB 4.39Å; I734-V754 HydrophobicContact CD1-CG1 3.63Å; I734-V754 HydrophobicContact CD1-CG2 4.05Å; V736-V754 HydrophobicContact CG1-CG2 4.03Å; F743-V754 HydrophobicContact CE2-CB 4.44Å; F743-V754 HydrophobicContact CE2-CG1 4.41Å; L746-V754 HydrophobicContact CD1-CG2 4.06Å; Q750-V754 WeakPolarHBondContact O-CG2 3.1Å; Q750-V754 PolarHBondContact O-N 2.97Å; Q750-V754 VanDerWaalsContact O-N 3.11Å; Q751-V754 PolarHBondContact O-N 2.66Å; V754-S756 PolarHBondContact O-N 3.48Å; V754-R757 WeakPolarHBondContact O-CB 3.28Å; V754-R757 PolarHBondContact O-N 3.19Å
755I94.7Very high92.4Very high18 Ų1848.7 Ų48.79%0.09225%0.253CS..Hα-helixtrans-65.6-26.3179.7-71.6171.5000112.1K714 L717 I718 M721 F743 Q751 E752 D753 R757K714-I755 HydrophobicContact CD-CG2 4.49Å; K714-I755 VanDerWaalsContact CE-CG2 3.41Å; K714-I755 WeakPolarHBondContact CE-O 3.37Å; K714-I755 HydrophobicContact CG-CG2 4.35Å; K714-I755 PolarHBondContact NZ-O 3.13Å; L717-I755 HydrophobicContact CB-CD1 4.2Å; L717-I755 HydrophobicContact CB-CG1 3.78Å; L717-I755 HydrophobicContact CD1-CG1 3.96Å; I718-I755 HydrophobicContact CG1-CD1 4.41Å; I718-I755 HydrophobicContact CG1-CG2 4.48Å; M721-I755 HydrophobicContact CB-CD1 4.39Å; M721-I755 HydrophobicContact CE-CD1 3.69Å; M721-I755 HydrophobicContact SD-CD1 3.54Å; M721-I755 VanDerWaalsContact SD-CD1 3.54Å; F743-I755 HydrophobicContact CZ-CD1 4.11Å; F743-I755 HydrophobicContact CZ-CG1 4.35Å; Q751-I755 WeakPolarHBondContact O-CB 3.36Å; Q751-I755 VanDerWaalsContact O-CG1 3.26Å; Q751-I755 WeakPolarHBondContact O-CG1 3.37Å; Q751-I755 PolarHBondContact O-N 2.8Å; E752-I755 PolarHBondContact O-N 2.92Å; D753-I755 VanDerWaalsContact C-N 3.34Å; D753-I755 PolarHBondContact O-N 3.01Å; I755-R757 VanDerWaalsContact C-N 3.33Å
756S92.4Very high92.4Very high57 Ų5748.2 Ų48.240%0.39925%0.25SC..Hα-helixtrans-79.4-14.1178.576.60000114Y644 E752 D753 V754Y644-S756 WeakPolarHBondContact CD1-OG 3.46Å; Y644-S756 WeakPolarHBondContact CE1-OG 3.36Å; E752-S756 WeakPolarHBondContact O-CB 3.44Å; E752-S756 PolarHBondContact O-N 3.46Å; E752-S756 PolarHBondContact O-OG 3.11Å; D753-S756 PolarHBondContact O-N 3.45Å; D753-S756 VanDerWaalsContact O-N 3.1Å; D753-S756 PolarHBondContact O-OG 2.91Å; V754-S756 PolarHBondContact O-N 3.48Å
757R93.4Very high92.5Very high24 Ų2450.4 Ų50.49%0.09126%0.261CS..SBendtrans-67.3167.7178-61.4175.2-170.5-168.5-0.4111.9Y644 V736 D753 V754 I755 F759Y644-R757 HydrophobicContact CD1-CG 4.37Å; Y644-R757 HydrophobicContact CE1-CG 3.7Å; V736-R757 PolarHBondContact O-NH1 2.79Å; D753-R757 PolarHBondContact O-N 3.41Å; D753-R757 IonicContact OD2-CZ 3.32Å; D753-R757 IonicContact OD2-NE 2.74Å; D753-R757 IonicContact OD2-NH2 2.86Å; D753-R757 PolarHBondContact OD2-NH2 3.23Å; V754-R757 WeakPolarHBondContact O-CB 3.28Å; V754-R757 PolarHBondContact O-N 3.19Å; I755-R757 VanDerWaalsContact C-N 3.33Å; R757-F759 WeakPolarHBondContact O-CD2 3.47Å; R757-F759 WeakPolarHBondContact O-CE2 3.36Å
758T94.1Very high92.6Very high30 Ų3048.9 Ų48.918%0.18425%0.249CC..  trans-68.1132.9176.3-52.10000111.2E647E647-T758 HydrophobicContact CB-CG2 3.94Å; E647-T758 WeakPolarHBondContact OE2-CB 3.27Å; E647-T758 PolarHBondContact OE2-OG1 3.39Å
759F94.4Very high92.7Very high29 Ų2944.8 Ų44.813%0.12724%0.238CC..  trans-119.6106.2167.9-69.3-97.1000107.4F712 K714 L717 R757 A761F712-F759 AromaticContact CD2-CE1 3.99Å; F712-F759 HydrophobicContact CD2-CE1 3.99Å; F712-F759 AromaticContact CE2-CE1 3.76Å; F712-F759 HydrophobicContact CE2-CE1 3.76Å; F712-F759 HydrophobicContact CE2-CZ 4.44Å; K714-F759 HydrophobicContact CB-CD1 4.37Å; K714-F759 HydrophobicContact CB-CD2 4.17Å; K714-F759 HydrophobicContact CB-CE2 4.37Å; K714-F759 HydrophobicContact CB-CG 4.2Å; K714-F759 HydrophobicContact CD-CD2 4.37Å; K714-F759 HydrophobicContact CG-CD2 4.41Å; K714-F759 HydrophobicContact CG-CE2 4.34Å; L717-F759 HydrophobicContact CD1-CE1 4.11Å; L717-F759 HydrophobicContact CD1-CZ 3.55Å; L717-F759 HydrophobicContact CG-CZ 4.47Å; R757-F759 WeakPolarHBondContact O-CD2 3.47Å; R757-F759 WeakPolarHBondContact O-CE2 3.36Å; F759-A761 PolarHBondContact O-N 2.8Å
760H95.7Very high93Very high8 Ų841.6 Ų41.64%0.03723%0.225CC..BIsolated β-bridgetrans-67.3121.7-175-70-72.2000110.5E647 L651 Q674 S675 I676 N677E647-H760 IonicContact OE1-CE1 2.95Å; E647-H760 PolarHBondContact OE1-CE1 3.15Å; E647-H760 IonicContact OE1-NE2 3.05Å; E647-H760 PolarHBondContact OE1-NE2 3.39Å; E647-H760 VanDerWaalsContact OE1-NE2 3.15Å; L651-H760 HydrophobicContact CB-CB 4.13Å; L651-H760 PolarHBondContact N-ND1 2.93Å; Q674-H760 PolarHBondContact OE1-CD2 3.43Å; Q674-H760 PolarHBondContact OE1-NE2 3.21Å; S675-H760 PolarHBondContact O-CD2 2.93Å; S675-H760 PolarHBondContact O-N 3.39Å; I676-H760 HydrophobicContact CB-CB 4.4Å; I676-H760 HydrophobicContact CG1-CB 4.24Å; N677-H760 PolarHBondContact N-O 2.89Å
761A93.1Very high93.2Very high78 Ų7843.5 Ų43.565%0.64524%0.237SC*.SBendtrans-94.4-0.8175.100000112.9A680 F759A680-A761 VanDerWaalsContact CB-C 3.43Å; F759-A761 PolarHBondContact O-N 2.8Å
762K93.2Very high93.2Very high114 Ų11445.9 Ų45.950%0.49625%0.25SS..  trans-153.6151.7176.261.6179.8-177.7177.10109.2L651L651-K762 PolarHBondContact N-O 3.48Å
763M89.6Confident93.2Very high79 Ų7941 Ų4139%0.38923%0.231SC..  trans-63.80167.4-73.6-167.4-84.100111.5L651 L652 I676 N691 V695L651-M763 PolarHBondContact N-OXT 2.83Å; L652-M763 WeakPolarHBondContact CB-OXT 3.33Å; L652-M763 HydrophobicContact CD1-CB 4.35Å; L652-M763 HydrophobicContact CG-CB 4.37Å; L652-M763 WeakPolarHBondContact CG-OXT 3.46Å; L652-M763 PolarHBondContact N-OXT 3.07Å; I676-M763 HydrophobicContact CD1-CG 4.41Å; N691-M763 HydrophobicContact CB-CE 4.38Å; N691-M763 HydrophobicContact CB-SD 4.3Å; V695-M763 HydrophobicContact CG2-SD 4.32Å

Retrieved 763 of 763 residues in 205.9 ms (Link to these results)