A0A077ZBU0_TRITR Loading...

Sialin

Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.

AlphaFold DB , UniProt , Accession A0A077ZBU0, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 506 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.1	Very low	31.4	Very low	245 Å²	245	152.8 Å²	152.8	100%	1.207	84%	0.839	S	S	*	*				0	87.2	0	-72.7	176.1	-177.2	0	0	108.2	N3	M1-N3 PolarHBondContact O-N 3.44Å
2	V	33	Very low	31.3	Very low	147 Å²	147	148.1 Å²	148.1	89%	0.891	83%	0.825	S	S	*	*			trans	-91.9	103.5	177.7	178.1	0	0	0	0	106.2	S4	V2-S4 PolarHBondContact O-N 3.16Å; V2-S4 VanDerWaalsContact O-N 3.12Å
3	N	32.3	Very low	31.3	Very low	139 Å²	139	148.6 Å²	148.6	74%	0.743	82%	0.824	S	S	*	*			trans	-76.8	97.9	-175.3	-142.6	-5.1	0	0	0	108.5	M1 R5	M1-N3 PolarHBondContact O-N 3.44Å; N3-R5 PolarHBondContact O-N 3.12Å; N3-R5 VanDerWaalsContact O-N 3.16Å
4	S	32.4	Very low	31.4	Very low	106 Å²	106	153.3 Å²	153.3	74%	0.741	83%	0.831	S	S	*	*			trans	-66.1	98.9	166.6	49.7	0	0	0	0	108.9	V2	V2-S4 PolarHBondContact O-N 3.16Å; V2-S4 VanDerWaalsContact O-N 3.12Å
5	R	32.5	Very low	31.4	Very low	222 Å²	222	154.5 Å²	154.5	84%	0.838	83%	0.829	S	S	*	*			trans	-110.9	102.6	161.8	-85.8	-172.5	175.6	-179.4	-1.5	109	N3 C7	N3-R5 PolarHBondContact O-N 3.12Å; N3-R5 VanDerWaalsContact O-N 3.16Å; R5-C7 PolarHBondContact O-N 3.49Å
6	E	30.6	Very low	31.3	Very low	184 Å²	184	157.1 Å²	157.1	86%	0.86	83%	0.831	S	S	*	*			trans	-34.5	116.8	156.1	-66.6	160.4	143.9	0	0	110.7
7	C	28.9	Very low	31.6	Very low	137 Å²	137	161.5 Å²	161.5	93%	0.926	83%	0.833	S	S	*	*			trans	-102.2	81.2	155	-150.4	0	0	0	0	105.4	R5	R5-C7 PolarHBondContact O-N 3.49Å
8	S	27.5	Very low	31.8	Very low	91 Å²	91	158.6 Å²	158.6	64%	0.636	83%	0.826	S	S	*	*			trans	-63.7	129.6	171.2	48	0	0	0	0	110.3
9	E	29.4	Very low	32	Very low	166 Å²	166	159.8 Å²	159.8	78%	0.776	83%	0.83	S	S	*	*			trans	66.5	84.2	141.1	-60.4	-175.2	147.7	0	0	118.5
10	S	31.5	Very low	32.6	Very low	127 Å²	127	155.6 Å²	155.6	89%	0.888	82%	0.82	S	S	*	*			trans	-102.3	67.6	138.7	71.6	0	0	0	0	109.3	S12	S10-S12 PolarHBondContact O-N 3.31Å
11	T	31.8	Very low	33	Very low	117 Å²	117	153 Å²	153	72%	0.718	81%	0.81	S	S	*	*			trans	-97.5	66.6	-179.9	-25.1	0	0	0	0	110.3
12	S	30.2	Very low	33.4	Very low	96 Å²	96	153.6 Å²	153.6	67%	0.671	80%	0.799	S	S	*	*			trans	-177.6	96.5	172.8	155	0	0	0	0	106	S10	S10-S12 PolarHBondContact O-N 3.31Å
13	L	31.5	Very low	34.4	Very low	155 Å²	155	154.3 Å²	154.3	81%	0.812	79%	0.79	S	S	*	*				-155	101.1	70.6	-72.6	150.1	0	0	0	107.6	E15	L13-E15 PolarHBondContact O-N 2.96Å
14	K	32.5	Very low	36.2	Very low	214 Å²	214	154.5 Å²	154.5	93%	0.93	79%	0.785	S	S	*	*			trans	-72.3	76.4	155.9	-86.9	-178.3	178.9	173.2	0	106.5	K16	K14-K16 PolarHBondContact O-N 2.77Å
15	E	32	Very low	38.5	Very low	172 Å²	172	150.4 Å²	150.4	80%	0.804	76%	0.757	S	S	*	*			trans	-52.6	109.4	166.7	-153.9	172.7	-156.4	0	0	105.9	L13 R17	L13-E15 PolarHBondContact O-N 2.96Å; E15-R17 VanDerWaalsContact C-N 3.27Å; E15-R17 PolarHBondContact O-N 2.85Å
16	K	30.4	Very low	41.1	Very low	196 Å²	196	141.3 Å²	141.3	85%	0.852	72%	0.723	S	S	*	*			trans	-55.5	97.7	174.4	-77.1	176	174.6	175.7	0	105.8	K14 P18	K14-K16 PolarHBondContact O-N 2.77Å; K16-P18 WeakPolarHBondContact O-CD 3.33Å
17	R	34.9	Very low	43.8	Very low	231 Å²	231	133.5 Å²	133.5	87%	0.872	69%	0.686	S	S	*	*			trans	-50.9	115.9	170.4	-73.6	-174	-170.9	-173.4	2.2	105.3	E15 M19	E15-R17 VanDerWaalsContact C-N 3.27Å; E15-R17 PolarHBondContact O-N 2.85Å; R17-M19 PolarHBondContact O-N 3.35Å; R17-M19 VanDerWaalsContact O-N 3.08Å
18	P	35.4	Very low	46.7	Very low	109 Å²	109	130.7 Å²	130.7	71%	0.708	66%	0.656	S	S	*	*			trans	-54.9	127.2	-179.9	21.2	-29.6	0	0	0	105.7	K16 A20	K16-P18 WeakPolarHBondContact O-CD 3.33Å; P18-A20 VanDerWaalsContact C-N 3.31Å; P18-A20 PolarHBondContact O-N 2.9Å
19	M	35.7	Very low	49.7	Very low	183 Å²	183	129.5 Å²	129.5	90%	0.901	64%	0.638	S	S	*	*			trans	-47.2	105.8	173.9	-85.2	-174.9	-85.3	0	0	106	R17 T21	R17-M19 PolarHBondContact O-N 3.35Å; R17-M19 VanDerWaalsContact O-N 3.08Å; M19-T21 VanDerWaalsContact C-N 3.31Å; M19-T21 PolarHBondContact O-N 2.74Å
20	A	43.6	Very low	52.6	Low	75 Å²	75	121.8 Å²	121.8	62%	0.62	60%	0.602	S	S	*	*			trans	-55.6	105.2	-175.2	0	0	0	0	0	105.2	P18 W22	P18-A20 VanDerWaalsContact C-N 3.31Å; P18-A20 PolarHBondContact O-N 2.9Å; A20-W22 PolarHBondContact O-N 2.75Å
21	T	41.6	Very low	55.4	Low	102 Å²	102	116 Å²	116	63%	0.626	56%	0.562	S	S	*	*			trans	-46.9	126.1	171.8	50.9	0	0	0	0	104.6	M19 K23	M19-T21 VanDerWaalsContact C-N 3.31Å; M19-T21 PolarHBondContact O-N 2.74Å; T21-K23 PolarHBondContact O-N 3.08Å
22	W	43.8	Very low	58.2	Low	257 Å²	257	114.7 Å²	114.7	97%	0.973	55%	0.55	S	S	*	.			trans	-62.1	41.1	178.8	-95.6	50	0	0	0	112.2	A20 F24	A20-W22 PolarHBondContact O-N 2.75Å; W22-F24 PolarHBondContact O-N 2.99Å
23	K	54.3	Low	61.2	Low	161 Å²	161	110.6 Å²	110.6	70%	0.7	52%	0.52	S	S	*	.			trans	-58.5	110.9	165.3	-74.6	-174.2	179	178.1	0	105.7	T21 A25	T21-K23 PolarHBondContact O-N 3.08Å; K23-A25 PolarHBondContact O-N 3.33Å
24	F	69.2	Low	64.1	Low	144 Å²	144	103.2 Å²	103.2	63%	0.632	48%	0.482	S	S	*	.			trans	-50.5	106	179.6	-157.9	-99.5	0	0	0	108.7	W22 R26	W22-F24 PolarHBondContact O-N 2.99Å; F24-R26 PolarHBondContact O-N 3.24Å
25	A	81.6	Confident	66.9	Low	20 Å²	20	94.4 Å²	94.4	17%	0.165	44%	0.443	C	S	.	.			trans	-56.3	141.6	-174.8	0	0	0	0	0	109.6	K23 R27 Y28 Y29	K23-A25 PolarHBondContact O-N 3.33Å; A25-R27 HydrophobicContact CB-CG 4.12Å; A25-R27 PolarHBondContact O-N 3.39Å; A25-R27 VanDerWaalsContact O-N 3.13Å; A25-Y28 HydrophobicContact CB-CD2 3.68Å; A25-Y28 HydrophobicContact CB-CE2 3.93Å; A25-Y28 PolarHBondContact O-N 3.03Å; A25-Y29 PolarHBondContact O-N 2.83Å
26	R	87.2	Confident	69.8	Low	30 Å²	30	90.1 Å²	90.1	11%	0.113	42%	0.424	C	S	.	.	H	α-helix	trans	-59.1	-31.8	-173	-168	63.1	170.6	155.7	4.3	111.6	F24 Y28 Y29 L30 W173 T231 D239 I242 E246	F24-R26 PolarHBondContact O-N 3.24Å; R26-Y28 VanDerWaalsContact C-N 3.32Å; R26-Y28 PolarHBondContact O-N 3.35Å; R26-Y29 VanDerWaalsContact NH1-CD1 3.28Å; R26-Y29 WeakPolarHBondContact O-CB 3.49Å; R26-Y29 PolarHBondContact O-N 3.37Å; R26-L30 PolarHBondContact O-N 3.14Å; R26-W173 HydrophobicContact CB-CZ3 4.43Å; R26-W173 HydrophobicContact CG-CH2 4.22Å; R26-W173 HydrophobicContact CG-CZ3 3.93Å; R26-T231 PolarHBondContact NH2-O 2.83Å; R26-D239 WeakPolarHBondContact CG-OD2 3.4Å; R26-D239 IonicContact CZ-OD2 3.56Å; R26-D239 IonicContact NE-OD1 2.76Å; R26-D239 IonicContact NE-OD2 3.47Å; R26-D239 PolarHBondContact NE-OD2 3.5Å; R26-D239 IonicContact NH2-OD1 2.73Å; R26-D239 IonicContact NH2-OD2 3.54Å; R26-D239 PolarHBondContact NH2-OD2 3.49Å; R26-I242 HydrophobicContact CB-CG1 4.29Å; R26-E246 VanDerWaalsContact CB-OE2 3.26Å; R26-E246 WeakPolarHBondContact CB-OE2 3.48Å; R26-E246 PolarHBondContact N-OE1 3.43Å; R26-E246 VanDerWaalsContact N-OE1 3.14Å; R26-E246 PolarHBondContact N-OE2 3.06Å
27	R	86.8	Confident	72.8	Confident	21 Å²	21	80.8 Å²	80.8	8%	0.079	38%	0.384	C	S	.	.	H	α-helix	trans	-59	-36.9	173.1	69.6	-178.3	-175.9	-103.8	8.6	113.7	A25 L30 T31 E178 E246	A25-R27 HydrophobicContact CB-CG 4.12Å; A25-R27 PolarHBondContact O-N 3.39Å; A25-R27 VanDerWaalsContact O-N 3.13Å; R27-L30 WeakPolarHBondContact O-CB 3.45Å; R27-L30 PolarHBondContact O-N 3.49Å; R27-T31 PolarHBondContact O-N 3.43Å; R27-T31 PolarHBondContact O-OG1 3Å; R27-E178 IonicContact CZ-OE1 3.51Å; R27-E178 IonicContact CZ-OE2 2.88Å; R27-E178 IonicContact NE-OE1 3.9Å; R27-E178 IonicContact NE-OE2 3.8Å; R27-E178 PolarHBondContact NE-OE2 2.95Å; R27-E178 IonicContact NH2-OE1 2.94Å; R27-E178 PolarHBondContact NH2-OE1 3.29Å; R27-E178 IonicContact NH2-OE2 3.86Å; R27-E178 PolarHBondContact NH2-OE2 3.34Å; R27-E178 VanDerWaalsContact NH2-OE2 3.15Å; R27-E246 WeakPolarHBondContact CB-OE1 3.41Å; R27-E246 WeakPolarHBondContact CG-OE1 3.5Å; R27-E246 PolarHBondContact N-OE1 3.35Å
28	Y	89	Confident	75.4	Confident	77 Å²	77	69.8 Å²	69.8	30%	0.302	34%	0.342	S	S	.	.	H	α-helix	trans	-73.2	-33.5	177.7	-63.3	-55.7	0	0	0	111.8	A25 R26 L30 T31 L32 E178 L182	A25-Y28 HydrophobicContact CB-CD2 3.68Å; A25-Y28 HydrophobicContact CB-CE2 3.93Å; A25-Y28 PolarHBondContact O-N 3.03Å; R26-Y28 VanDerWaalsContact C-N 3.32Å; R26-Y28 PolarHBondContact O-N 3.35Å; Y28-L30 VanDerWaalsContact C-N 3.34Å; Y28-T31 WeakPolarHBondContact O-CB 3.22Å; Y28-T31 PolarHBondContact O-N 3.12Å; Y28-L32 WeakPolarHBondContact O-CB 3.35Å; Y28-L32 PolarHBondContact O-N 2.9Å; Y28-E178 PolarHBondContact OH-OE2 3.3Å; Y28-L182 HydrophobicContact CD1-CD2 4.02Å; Y28-L182 HydrophobicContact CE1-CD2 3.88Å
29	Y	90.2	Very high	78	Confident	67 Å²	67	65.2 Å²	65.2	26%	0.263	31%	0.312	S	S	.	.	H	α-helix	trans	-62	-44.6	169.6	175.4	-95.7	0	0	0	110.9	A25 R26 T31 L32 I33 T231	A25-Y29 PolarHBondContact O-N 2.83Å; R26-Y29 VanDerWaalsContact NH1-CD1 3.28Å; R26-Y29 WeakPolarHBondContact O-CB 3.49Å; R26-Y29 PolarHBondContact O-N 3.37Å; Y29-T31 VanDerWaalsContact C-N 3.34Å; Y29-T31 PolarHBondContact O-N 3.06Å; Y29-L32 PolarHBondContact O-N 3.13Å; Y29-I33 HydrophobicContact CE1-CG2 4.46Å; Y29-I33 WeakPolarHBondContact O-CG2 3.48Å; Y29-I33 PolarHBondContact O-N 3.16Å; Y29-T231 WeakPolarHBondContact OH-CB 3.46Å; Y29-T231 PolarHBondContact OH-OG1 3.48Å
30	L	90.3	Very high	80.7	Confident	4 Å²	4	57.8 Å²	57.8	2%	0.021	28%	0.276	C	S	.	.	H	α-helix	trans	-60	-42.6	174.4	-177.2	65.3	0	0	0	111.9	R26 R27 Y28 I33 A34 W170 W173 W228 V232	R26-L30 PolarHBondContact O-N 3.14Å; R27-L30 WeakPolarHBondContact O-CB 3.45Å; R27-L30 PolarHBondContact O-N 3.49Å; Y28-L30 VanDerWaalsContact C-N 3.34Å; L30-I33 HydrophobicContact CD1-CG2 4.45Å; L30-I33 WeakPolarHBondContact O-CG2 3.31Å; L30-A34 WeakPolarHBondContact O-CB 3.48Å; L30-A34 PolarHBondContact O-N 3.23Å; L30-W170 HydrophobicContact CD2-CH2 4.47Å; L30-W170 HydrophobicContact CD2-CZ3 4.17Å; L30-W173 HydrophobicContact CD2-CB 3.7Å; L30-W173 HydrophobicContact CD2-CD2 3.57Å; L30-W173 HydrophobicContact CD2-CE3 3.94Å; L30-W173 HydrophobicContact CD2-CG 3.47Å; L30-W173 VanDerWaalsContact CD2-CG 3.47Å; L30-W228 HydrophobicContact CD1-CH2 3.52Å; L30-W228 HydrophobicContact CD1-CZ2 4.42Å; L30-W228 HydrophobicContact CD1-CZ3 3.8Å; L30-V232 HydrophobicContact CD1-CB 4.29Å; L30-V232 HydrophobicContact CD1-CG1 3.5Å; L30-V232 VanDerWaalsContact CD1-CG1 3.5Å; L30-V232 HydrophobicContact CD1-CG2 3.75Å
31	T	90.3	Very high	82.9	Confident	6 Å²	6	54.2 Å²	54.2	4%	0.037	25%	0.247	C	C	.	.	H	α-helix	trans	-58.2	-47.9	174	-56.8	0	0	0	0	111.3	R27 Y28 Y29 A34 F35 W170 L182 I185 V186	R27-T31 PolarHBondContact O-N 3.43Å; R27-T31 PolarHBondContact O-OG1 3Å; Y28-T31 WeakPolarHBondContact O-CB 3.22Å; Y28-T31 PolarHBondContact O-N 3.12Å; Y29-T31 VanDerWaalsContact C-N 3.34Å; Y29-T31 PolarHBondContact O-N 3.06Å; T31-A34 PolarHBondContact O-N 2.99Å; T31-F35 VanDerWaalsContact O-CB 3.28Å; T31-F35 WeakPolarHBondContact O-CB 3.38Å; T31-F35 PolarHBondContact O-N 3.2Å; T31-W170 VanDerWaalsContact OG1-CH2 3.26Å; T31-W170 WeakPolarHBondContact OG1-CH2 3.41Å; T31-L182 HydrophobicContact CG2-CD2 4.44Å; T31-L182 WeakPolarHBondContact OG1-CD2 3.43Å; T31-I185 HydrophobicContact CG2-CB 3.85Å; T31-I185 HydrophobicContact CG2-CD1 4.41Å; T31-I185 HydrophobicContact CG2-CG2 3.49Å; T31-I185 VanDerWaalsContact CG2-CG2 3.49Å; T31-V186 HydrophobicContact CG2-CG2 3.88Å
32	L	92.3	Very high	85.1	Confident	88 Å²	88	50.2 Å²	50.2	46%	0.461	22%	0.22	S	C	.	.	H	α-helix	trans	-65.8	-46.9	-176.5	-176.7	66	0	0	0	111.9	Y28 Y29 A34 F35 M36	Y28-L32 WeakPolarHBondContact O-CB 3.35Å; Y28-L32 PolarHBondContact O-N 2.9Å; Y29-L32 PolarHBondContact O-N 3.13Å; L32-A34 VanDerWaalsContact C-N 3.35Å; L32-F35 WeakPolarHBondContact O-CB 3.26Å; L32-F35 PolarHBondContact O-N 2.89Å; L32-M36 HydrophobicContact CD1-CE 4.3Å; L32-M36 WeakPolarHBondContact O-CG 3.37Å; L32-M36 PolarHBondContact O-N 3.47Å
33	I	93.2	Very high	87.3	Confident	11 Å²	11	38.8 Å²	38.8	6%	0.056	18%	0.181	C	C	.	.	H	α-helix	trans	-67.8	-36.7	178.6	-166.4	176.3	0	0	0	111.3	Y29 L30 M36 G37 W224 L227 W228 T231 V232	Y29-I33 HydrophobicContact CE1-CG2 4.46Å; Y29-I33 WeakPolarHBondContact O-CG2 3.48Å; Y29-I33 PolarHBondContact O-N 3.16Å; L30-I33 HydrophobicContact CD1-CG2 4.45Å; L30-I33 WeakPolarHBondContact O-CG2 3.31Å; I33-M36 PolarHBondContact O-N 3.07Å; I33-G37 PolarHBondContact O-N 2.64Å; I33-W224 HydrophobicContact CG1-CZ2 4.48Å; I33-W224 WeakPolarHBondContact O-CZ2 3.37Å; I33-W224 PolarHBondContact O-NE1 2.99Å; I33-L227 HydrophobicContact CD1-CD2 4.01Å; I33-L227 HydrophobicContact CD1-CG 3.94Å; I33-W228 HydrophobicContact CD1-CB 4.48Å; I33-W228 HydrophobicContact CD1-CE3 4.25Å; I33-W228 HydrophobicContact CG1-CE3 4.16Å; I33-W228 HydrophobicContact CG2-CE3 3.84Å; I33-W228 HydrophobicContact CG2-CZ3 3.71Å; I33-T231 WeakPolarHBondContact CD1-OG1 3.21Å; I33-V232 HydrophobicContact CG2-CG2 4.11Å
34	A	91.3	Very high	89.1	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-65.3	-44.7	173.9	0	0	0	0	0	111.8	L30 T31 L32 M36 G37 F38 M166 V186 W228	L30-A34 WeakPolarHBondContact O-CB 3.48Å; L30-A34 PolarHBondContact O-N 3.23Å; T31-A34 PolarHBondContact O-N 2.99Å; L32-A34 VanDerWaalsContact C-N 3.35Å; A34-M36 VanDerWaalsContact C-N 3.31Å; A34-M36 PolarHBondContact O-N 2.9Å; A34-G37 WeakPolarHBondContact O-CA 3.41Å; A34-G37 PolarHBondContact O-N 3.14Å; A34-F38 WeakPolarHBondContact O-CD2 3.4Å; A34-F38 PolarHBondContact O-N 3.46Å; A34-M166 HydrophobicContact CB-CE 3.54Å; A34-M166 HydrophobicContact CB-SD 3.77Å; A34-V186 HydrophobicContact CB-CB 4.46Å; A34-V186 HydrophobicContact CB-CG1 3.78Å; A34-V186 HydrophobicContact CB-CG2 3.75Å; A34-W228 HydrophobicContact CB-CH2 4.41Å; A34-W228 HydrophobicContact CB-CZ3 4.02Å
35	F	91.6	Very high	90	Very high	29 Å²	29	25 Å²	25	13%	0.127	12%	0.12	C	C	.	.	H	α-helix	trans	-52.1	-49.8	173	170.3	-90.5	0	0	0	111	T31 L32 G37 F38 C39 I185 S188 G189 F192	T31-F35 VanDerWaalsContact O-CB 3.28Å; T31-F35 WeakPolarHBondContact O-CB 3.38Å; T31-F35 PolarHBondContact O-N 3.2Å; L32-F35 WeakPolarHBondContact O-CB 3.26Å; L32-F35 PolarHBondContact O-N 2.89Å; F35-G37 VanDerWaalsContact C-N 3.26Å; F35-G37 PolarHBondContact O-N 2.84Å; F35-F38 PolarHBondContact O-N 3.34Å; F35-F38 VanDerWaalsContact O-N 3.13Å; F35-C39 VanDerWaalsContact CE1-SG 3.54Å; F35-C39 PolarHBondContact O-N 2.99Å; F35-C39 PolarHBondContact O-SG 3.5Å; F35-I185 VanDerWaalsContact CD2-O 3.27Å; F35-I185 WeakPolarHBondContact CD2-O 3.27Å; F35-S188 WeakPolarHBondContact CE2-OG 3.44Å; F35-G189 VanDerWaalsContact CE2-N 3.32Å; F35-F192 AromaticContact CE1-CD1 3.97Å; F35-F192 HydrophobicContact CE1-CD1 3.97Å; F35-F192 HydrophobicContact CE1-CE1 4.36Å; F35-F192 HydrophobicContact CE1-CG 4.45Å; F35-F192 HydrophobicContact CE2-CB 4.31Å; F35-F192 HydrophobicContact CZ-CB 3.82Å; F35-F192 AromaticContact CZ-CD1 3.75Å; F35-F192 HydrophobicContact CZ-CD1 3.75Å; F35-F192 HydrophobicContact CZ-CD2 4.47Å; F35-F192 HydrophobicContact CZ-CE1 4.39Å; F35-F192 AromaticContact CZ-CG 3.77Å; F35-F192 HydrophobicContact CZ-CG 3.77Å
36	M	93.7	Very high	90.4	Very high	81 Å²	81	24.2 Å²	24.2	40%	0.399	11%	0.113	S	C	.	.	H	α-helix	trans	-61	-35.3	176.4	-67.3	-60.4	161.3	0	0	112.6	L32 I33 A34 C39 I40	L32-M36 HydrophobicContact CD1-CE 4.3Å; L32-M36 WeakPolarHBondContact O-CG 3.37Å; L32-M36 PolarHBondContact O-N 3.47Å; I33-M36 PolarHBondContact O-N 3.07Å; A34-M36 VanDerWaalsContact C-N 3.31Å; A34-M36 PolarHBondContact O-N 2.9Å; M36-C39 WeakPolarHBondContact O-CB 3.29Å; M36-C39 PolarHBondContact O-N 3.46Å; M36-I40 WeakPolarHBondContact O-CG1 3.45Å; M36-I40 PolarHBondContact O-N 2.8Å
37	G	92.2	Very high	90.6	Very high	0 Å²	0	23 Å²	23	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-62.2	-44.5	173.7	0	0	0	0	0	112.7	I33 A34 F35 C39 I40 L41	I33-G37 PolarHBondContact O-N 2.64Å; A34-G37 WeakPolarHBondContact O-CA 3.41Å; A34-G37 PolarHBondContact O-N 3.14Å; F35-G37 VanDerWaalsContact C-N 3.26Å; F35-G37 PolarHBondContact O-N 2.84Å; G37-C39 VanDerWaalsContact C-N 3.34Å; G37-I40 PolarHBondContact O-N 2.93Å; G37-L41 VanDerWaalsContact O-CB 3.27Å; G37-L41 WeakPolarHBondContact O-CB 3.48Å; G37-L41 PolarHBondContact O-N 2.8Å
38	F	89.5	Confident	90.8	Very high	1 Å²	1	22 Å²	22	0%	0.004	11%	0.106	C	C	.	.	H	α-helix	trans	-66.8	-34.6	174.9	-81.2	-86.8	0	0	0	112.4	A34 F35 L41 Y42 Y163 M166 V186 Y187	A34-F38 WeakPolarHBondContact O-CD2 3.4Å; A34-F38 PolarHBondContact O-N 3.46Å; F35-F38 PolarHBondContact O-N 3.34Å; F35-F38 VanDerWaalsContact O-N 3.13Å; F38-L41 PolarHBondContact O-N 3.45Å; F38-Y42 PolarHBondContact O-N 2.76Å; F38-Y42 VanDerWaalsContact O-N 3.08Å; F38-Y163 AromaticContact CD1-CE1 3.99Å; F38-Y163 HydrophobicContact CD1-CE1 3.99Å; F38-Y163 HydrophobicContact CD1-CE2 4.34Å; F38-Y163 AromaticContact CD1-CZ 3.79Å; F38-Y163 AromaticContact CE1-CD1 3.67Å; F38-Y163 HydrophobicContact CE1-CD1 3.67Å; F38-Y163 HydrophobicContact CE1-CD2 4.09Å; F38-Y163 AromaticContact CE1-CE1 3.41Å; F38-Y163 HydrophobicContact CE1-CE1 3.41Å; F38-Y163 VanDerWaalsContact CE1-CE1 3.41Å; F38-Y163 AromaticContact CE1-CE2 3.83Å; F38-Y163 HydrophobicContact CE1-CE2 3.83Å; F38-Y163 AromaticContact CE1-CG 4Å; F38-Y163 HydrophobicContact CE1-CG 4Å; F38-Y163 AromaticContact CE1-CZ 3.46Å; F38-Y163 VanDerWaalsContact CE1-CZ 3.46Å; F38-Y163 HydrophobicContact CZ-CD1 4.31Å; F38-Y163 HydrophobicContact CZ-CE1 4.41Å; F38-M166 HydrophobicContact CE2-CB 4.19Å; F38-M166 HydrophobicContact CE2-CG 4.12Å; F38-M166 HydrophobicContact CZ-CB 4.17Å; F38-V186 HydrophobicContact CD2-CG1 3.27Å; F38-V186 HydrophobicContact CE2-CG1 3.32Å; F38-V186 HydrophobicContact CG-CG1 4.29Å; F38-V186 HydrophobicContact CZ-CG1 4.38Å; F38-Y187 HydrophobicContact CD1-CD1 4.31Å; F38-Y187 AromaticContact CE1-CD1 3.86Å; F38-Y187 HydrophobicContact CE1-CD1 3.86Å; F38-Y187 AromaticContact CE1-CE1 3.9Å; F38-Y187 HydrophobicContact CE1-CE1 3.9Å; F38-Y187 HydrophobicContact CE2-CE1 4.42Å; F38-Y187 AromaticContact CZ-CD1 3.96Å; F38-Y187 HydrophobicContact CZ-CD1 3.96Å; F38-Y187 AromaticContact CZ-CE1 3.69Å; F38-Y187 HydrophobicContact CZ-CE1 3.69Å
39	C	91.3	Very high	90.8	Very high	12 Å²	12	18.7 Å²	18.7	8%	0.081	9%	0.093	C	C	.	.	H	α-helix	trans	-58.3	-51.8	171.6	-62.8	0	0	0	0	111.4	F35 M36 G37 L41 Y42 A43 G189 G193	F35-C39 VanDerWaalsContact CE1-SG 3.54Å; F35-C39 PolarHBondContact O-N 2.99Å; F35-C39 PolarHBondContact O-SG 3.5Å; M36-C39 WeakPolarHBondContact O-CB 3.29Å; M36-C39 PolarHBondContact O-N 3.46Å; G37-C39 VanDerWaalsContact C-N 3.34Å; C39-L41 VanDerWaalsContact C-N 3.34Å; C39-L41 PolarHBondContact O-N 3.25Å; C39-Y42 PolarHBondContact O-N 2.98Å; C39-A43 WeakPolarHBondContact O-CB 3.24Å; C39-A43 PolarHBondContact O-N 2.71Å; C39-G189 WeakPolarHBondContact CA-O 3.49Å; C39-G189 PolarHBondContact N-O 3.47Å; C39-G189 VanDerWaalsContact SG-CA 3.54Å; C39-G189 PolarHBondContact SG-O 3.08Å; C39-G193 WeakPolarHBondContact O-CA 3.48Å
40	I	92.5	Very high	90.8	Very high	27 Å²	27	15.5 Å²	15.5	14%	0.138	8%	0.081	C	C	.	.	H	α-helix	trans	-65.6	-39.2	-179.2	-65	163.3	0	0	0	111.1	M36 G37 Y42 A43 M44 F220 W224	M36-I40 WeakPolarHBondContact O-CG1 3.45Å; M36-I40 PolarHBondContact O-N 2.8Å; G37-I40 PolarHBondContact O-N 2.93Å; I40-Y42 VanDerWaalsContact C-N 3.34Å; I40-Y42 PolarHBondContact O-N 3.25Å; I40-A43 WeakPolarHBondContact O-CB 3.49Å; I40-A43 PolarHBondContact O-N 2.95Å; I40-M44 HydrophobicContact CG2-CE 3.99Å; I40-M44 HydrophobicContact CG2-CG 4.47Å; I40-M44 HydrophobicContact CG2-SD 4.43Å; I40-M44 WeakPolarHBondContact O-CG 2.9Å; I40-M44 PolarHBondContact O-N 2.94Å; I40-F220 HydrophobicContact CD1-CB 4.47Å; I40-W224 HydrophobicContact CD1-CB 3.57Å; I40-W224 HydrophobicContact CD1-CG 3.71Å
41	L	89.4	Confident	90.9	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-59.2	-44.4	178	-173.2	150.2	0	0	0	111.8	G37 F38 C39 R45 I119 Q151 T162 Y163	G37-L41 VanDerWaalsContact O-CB 3.27Å; G37-L41 WeakPolarHBondContact O-CB 3.48Å; G37-L41 PolarHBondContact O-N 2.8Å; F38-L41 PolarHBondContact O-N 3.45Å; C39-L41 VanDerWaalsContact C-N 3.34Å; C39-L41 PolarHBondContact O-N 3.25Å; L41-R45 PolarHBondContact O-N 2.85Å; L41-I119 HydrophobicContact CB-CD1 4.41Å; L41-I119 HydrophobicContact CD1-CD1 4.29Å; L41-I119 HydrophobicContact CD1-CG1 4.16Å; L41-Q151 HydrophobicContact CG-CG 4.34Å; L41-Q151 PolarHBondContact O-NE2 3.47Å; L41-Q151 VanDerWaalsContact O-NE2 3.15Å; L41-T162 HydrophobicContact CD1-CG2 3.63Å; L41-Y163 HydrophobicContact CD2-CE2 4.18Å
42	Y	87.5	Confident	90.9	Very high	19 Å²	19	15.4 Å²	15.4	8%	0.075	8%	0.08	C	C	.	.	H	α-helix	trans	-75.1	-35.3	176.4	-95.3	-121.7	0	0	0	112.3	F38 C39 I40 M44 R45 V46 Y163 S190 T194	F38-Y42 PolarHBondContact O-N 2.76Å; F38-Y42 VanDerWaalsContact O-N 3.08Å; C39-Y42 PolarHBondContact O-N 2.98Å; I40-Y42 VanDerWaalsContact C-N 3.34Å; I40-Y42 PolarHBondContact O-N 3.25Å; Y42-M44 PolarHBondContact O-N 2.78Å; Y42-R45 VanDerWaalsContact CZ-NH1 3.34Å; Y42-R45 WeakPolarHBondContact O-CA 3.44Å; Y42-R45 WeakPolarHBondContact O-CB 3.35Å; Y42-R45 PolarHBondContact O-N 3.14Å; Y42-R45 PolarHBondContact OH-NH1 3.4Å; Y42-V46 WeakPolarHBondContact O-CG1 3.31Å; Y42-V46 WeakPolarHBondContact O-CG2 3.35Å; Y42-V46 PolarHBondContact O-N 3.13Å; Y42-Y163 HydrophobicContact CE2-CE2 4.45Å; Y42-Y163 WeakPolarHBondContact CE2-OH 3.42Å; Y42-Y163 PolarHBondContact OH-OH 2.92Å; Y42-S190 WeakPolarHBondContact CB-O 3.46Å; Y42-S190 WeakPolarHBondContact CD1-O 2.87Å; Y42-S190 VanDerWaalsContact CD2-CB 3.46Å; Y42-T194 WeakPolarHBondContact CD1-OG1 3.28Å
43	A	90.7	Very high	90.7	Very high	17 Å²	17	11.5 Å²	11.5	14%	0.14	6%	0.059	C	C	.	.	H	α-helix	trans	-55.3	-53.6	173	0	0	0	0	0	111.3	C39 I40 R45 V46 N47 A197	C39-A43 WeakPolarHBondContact O-CB 3.24Å; C39-A43 PolarHBondContact O-N 2.71Å; I40-A43 WeakPolarHBondContact O-CB 3.49Å; I40-A43 PolarHBondContact O-N 2.95Å; A43-R45 PolarHBondContact O-N 3.01Å; A43-R45 VanDerWaalsContact O-N 3.08Å; A43-V46 PolarHBondContact O-N 3.44Å; A43-V46 VanDerWaalsContact O-N 3.16Å; A43-N47 WeakPolarHBondContact O-CB 3.43Å; A43-N47 PolarHBondContact O-N 3.11Å; A43-N47 PolarHBondContact O-ND2 2.68Å; A43-N47 PolarHBondContact O-OD1 3.33Å; A43-A197 VanDerWaalsContact CA-CB 3.46Å; A43-A197 HydrophobicContact CB-CB 3.49Å; A43-A197 VanDerWaalsContact CB-CB 3.49Å
44	M	90.4	Very high	90.5	Very high	5 Å²	5	11.6 Å²	11.6	3%	0.025	6%	0.059	C	C	.	.	H	α-helix	trans	-60.1	-23.9	176.6	-68.4	-174.4	-63.8	0	0	113.5	I40 Y42 I119 C122	I40-M44 HydrophobicContact CG2-CE 3.99Å; I40-M44 HydrophobicContact CG2-CG 4.47Å; I40-M44 HydrophobicContact CG2-SD 4.43Å; I40-M44 WeakPolarHBondContact O-CG 2.9Å; I40-M44 PolarHBondContact O-N 2.94Å; Y42-M44 PolarHBondContact O-N 2.78Å; M44-I119 HydrophobicContact CE-CG2 4.16Å; M44-C122 HydrophobicContact CE-CB 3.97Å; M44-C122 HydrophobicContact SD-CB 4.45Å
45	R	89.1	Confident	90.3	Very high	10 Å²	10	11.6 Å²	11.6	4%	0.038	6%	0.059	C	C	.	.	H	α-helix	trans	-76.4	-45.6	176.7	-174.6	179.9	-64	-178.6	0.7	112	L41 Y42 A43 F91	L41-R45 PolarHBondContact O-N 2.85Å; Y42-R45 VanDerWaalsContact CZ-NH1 3.34Å; Y42-R45 WeakPolarHBondContact O-CA 3.44Å; Y42-R45 WeakPolarHBondContact O-CB 3.35Å; Y42-R45 PolarHBondContact O-N 3.14Å; Y42-R45 PolarHBondContact OH-NH1 3.4Å; A43-R45 PolarHBondContact O-N 3.01Å; A43-R45 VanDerWaalsContact O-N 3.08Å; R45-F91 HydrophobicContact CG-CD1 4.29Å; R45-F91 HydrophobicContact CG-CE1 4.18Å
46	V	89.3	Confident	90	Very high	3 Å²	3	11.8 Å²	11.8	2%	0.018	6%	0.063	C	C	.	.	H	α-helix	trans	-89.1	-23.9	-170.8	-56.4	0	0	0	0	113.7	Y42 A43 L48 S49 T194 A197 I198 L295	Y42-V46 WeakPolarHBondContact O-CG1 3.31Å; Y42-V46 WeakPolarHBondContact O-CG2 3.35Å; Y42-V46 PolarHBondContact O-N 3.13Å; A43-V46 PolarHBondContact O-N 3.44Å; A43-V46 VanDerWaalsContact O-N 3.16Å; V46-L48 PolarHBondContact O-N 3.19Å; V46-S49 PolarHBondContact O-N 3.48Å; V46-S49 PolarHBondContact O-OG 2.88Å; V46-T194 HydrophobicContact CG1-CG2 4.17Å; V46-A197 HydrophobicContact CG2-CB 3.67Å; V46-I198 HydrophobicContact CB-CG1 4.49Å; V46-I198 HydrophobicContact CG2-CG1 4.12Å; V46-L295 HydrophobicContact CG1-CD1 3.74Å; V46-L295 HydrophobicContact CG1-CD2 4.05Å; V46-L295 HydrophobicContact CG1-CG 4.04Å
47	N	91.2	Very high	89.3	Confident	5 Å²	5	9.6 Å²	9.6	3%	0.027	5%	0.054	C	C	.	.	H	α-helix	trans	-53	-32.8	-176.5	-75.4	2.6	0	0	0	113.5	A43 S49 I50 A51 A197 S201 V213 F214 S217	A43-N47 WeakPolarHBondContact O-CB 3.43Å; A43-N47 PolarHBondContact O-N 3.11Å; A43-N47 PolarHBondContact O-ND2 2.68Å; A43-N47 PolarHBondContact O-OD1 3.33Å; N47-S49 PolarHBondContact O-N 3.19Å; N47-I50 PolarHBondContact O-N 2.99Å; N47-A51 WeakPolarHBondContact O-CB 3.47Å; N47-A51 PolarHBondContact O-N 3.29Å; N47-A197 WeakPolarHBondContact OD1-CB 3.33Å; N47-S201 PolarHBondContact OD1-OG 3.49Å; N47-V213 HydrophobicContact CB-CG1 3.69Å; N47-F214 HydrophobicContact CB-CE1 4.39Å; N47-S217 WeakPolarHBondContact ND2-CB 3.28Å; N47-S217 PolarHBondContact ND2-OG 3.03Å; N47-S217 VanDerWaalsContact ND2-OG 3.12Å
48	L	91.8	Very high	88.1	Confident	1 Å²	1	14.3 Å²	14.3	1%	0.005	8%	0.079	C	C	.	.	H	α-helix	trans	-65	-34.4	177.6	-176.3	63.1	0	0	0	113.2	V46 I50 A51 I52 M55 V87 L88 R144 F214	V46-L48 PolarHBondContact O-N 3.19Å; L48-I50 PolarHBondContact O-N 3.11Å; L48-A51 PolarHBondContact O-N 3.33Å; L48-I52 WeakPolarHBondContact O-CB 3.43Å; L48-I52 WeakPolarHBondContact O-CG2 3.39Å; L48-I52 PolarHBondContact O-N 3.24Å; L48-M55 HydrophobicContact CD1-SD 4.32Å; L48-V87 HydrophobicContact CD1-CG1 4.46Å; L48-V87 HydrophobicContact CD2-CG1 3.87Å; L48-L88 HydrophobicContact CD2-CD2 4.35Å; L48-L88 HydrophobicContact CG-CD2 4.07Å; L48-R144 HydrophobicContact CD2-CG 4.42Å; L48-F214 HydrophobicContact CB-CE1 4.29Å; L48-F214 HydrophobicContact CB-CZ 4.27Å; L48-F214 HydrophobicContact CD1-CE1 4.46Å; L48-F214 HydrophobicContact CD1-CZ 3.77Å
49	S	89.4	Confident	86.8	Confident	6 Å²	6	15.8 Å²	15.8	4%	0.042	9%	0.089	C	C	.	.	H	α-helix	trans	-67.8	-23.4	-179.9	64	0	0	0	0	113	V46 N47 I52 L295 T296	V46-S49 PolarHBondContact O-N 3.48Å; V46-S49 PolarHBondContact O-OG 2.88Å; N47-S49 PolarHBondContact O-N 3.19Å; S49-I52 WeakPolarHBondContact O-CG2 3.43Å; S49-L295 WeakPolarHBondContact CB-O 3.43Å; S49-L295 PolarHBondContact OG-O 3Å; S49-T296 WeakPolarHBondContact CB-O 3.39Å
50	I	90.5	Very high	84.9	Confident	1 Å²	1	18.5 Å²	18.5	1%	0.005	11%	0.107	C	C	.	.	H	α-helix	trans	-87.7	-49.5	170.3	-65.2	-67.4	0	0	0	110.9	N47 L48 I52 L53 Y54 I198 A202 P299	N47-I50 PolarHBondContact O-N 2.99Å; L48-I50 PolarHBondContact O-N 3.11Å; I50-I52 PolarHBondContact O-N 3.3Å; I50-L53 WeakPolarHBondContact O-CB 3.33Å; I50-L53 PolarHBondContact O-N 3.15Å; I50-L53 VanDerWaalsContact O-N 3.13Å; I50-Y54 HydrophobicContact CG2-CE2 4.04Å; I50-Y54 WeakPolarHBondContact O-CD2 3.44Å; I50-I198 HydrophobicContact CD1-CG2 3.74Å; I50-I198 HydrophobicContact CG1-CB 4.46Å; I50-I198 HydrophobicContact CG1-CG2 3.85Å; I50-A202 HydrophobicContact CG2-CB 3.94Å; I50-P299 HydrophobicContact CD1-CB 3.61Å; I50-P299 HydrophobicContact CD1-CG 3.54Å; I50-P299 HydrophobicContact CG1-CG 4.41Å
51	A	91.6	Very high	82.9	Confident	0 Å²	0	20.8 Å²	20.8	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-58.8	-34.7	-177.1	0	0	0	0	0	112.4	N47 L48 L53 Y54 M55 F214	N47-A51 WeakPolarHBondContact O-CB 3.47Å; N47-A51 PolarHBondContact O-N 3.29Å; L48-A51 PolarHBondContact O-N 3.33Å; A51-L53 PolarHBondContact O-N 3.23Å; A51-Y54 PolarHBondContact O-N 2.9Å; A51-M55 VanDerWaalsContact O-CG 3.27Å; A51-M55 WeakPolarHBondContact O-CG 3.38Å; A51-M55 PolarHBondContact O-N 3.41Å; A51-F214 HydrophobicContact CB-CE2 3.75Å; A51-F214 HydrophobicContact CB-CZ 3.67Å
52	I	90.3	Very high	80.9	Confident	7 Å²	7	29 Å²	29	4%	0.036	15%	0.153	C	C	.	.	H	α-helix	trans	-61.4	-29.5	-179.3	-159	64.1	0	0	0	112.9	L48 S49 I50 Y54 M55 T56 W79 V84 V87 L88	L48-I52 WeakPolarHBondContact O-CB 3.43Å; L48-I52 WeakPolarHBondContact O-CG2 3.39Å; L48-I52 PolarHBondContact O-N 3.24Å; S49-I52 WeakPolarHBondContact O-CG2 3.43Å; I50-I52 PolarHBondContact O-N 3.3Å; I52-Y54 VanDerWaalsContact C-N 3.35Å; I52-M55 HydrophobicContact CD1-CB 4.36Å; I52-M55 HydrophobicContact CD1-CE 4.2Å; I52-M55 HydrophobicContact CD1-SD 4.01Å; I52-M55 PolarHBondContact O-N 3.13Å; I52-T56 HydrophobicContact CD1-CG2 4.14Å; I52-T56 HydrophobicContact CG1-CG2 4.2Å; I52-T56 WeakPolarHBondContact O-CB 3.42Å; I52-T56 WeakPolarHBondContact O-CG2 3.35Å; I52-T56 PolarHBondContact O-N 2.82Å; I52-T56 PolarHBondContact O-OG1 3.29Å; I52-W79 HydrophobicContact CD1-CE3 4.38Å; I52-W79 HydrophobicContact CD1-CZ3 4.06Å; I52-V84 HydrophobicContact CD1-CG1 4.49Å; I52-V84 HydrophobicContact CG1-CG1 3.8Å; I52-V87 HydrophobicContact CD1-CG1 4.48Å; I52-L88 HydrophobicContact CG2-CD2 4.29Å
53	L	87.8	Confident	78.8	Confident	6 Å²	6	30.1 Å²	30.1	3%	0.031	16%	0.16	C	C	.	.	H	α-helix	trans	-64.6	-42.3	175.2	-64	176.6	0	0	0	111.1	I50 A51 M55 T57 P299 A300 L310 T313	I50-L53 WeakPolarHBondContact O-CB 3.33Å; I50-L53 PolarHBondContact O-N 3.15Å; I50-L53 VanDerWaalsContact O-N 3.13Å; A51-L53 PolarHBondContact O-N 3.23Å; L53-M55 VanDerWaalsContact C-N 3.35Å; L53-T57 WeakPolarHBondContact O-CB 3.46Å; L53-T57 PolarHBondContact O-N 3.42Å; L53-T57 PolarHBondContact O-OG1 2.94Å; L53-P299 HydrophobicContact CD1-CB 3.66Å; L53-A300 HydrophobicContact CD2-CB 3.93Å; L53-L310 HydrophobicContact CB-CD2 3.67Å; L53-L310 HydrophobicContact CD1-CD2 4.07Å; L53-L310 HydrophobicContact CG-CD2 4.43Å; L53-T313 HydrophobicContact CD1-CG2 4.24Å
54	Y	88.3	Confident	76.8	Confident	14 Å²	14	34.7 Å²	34.7	6%	0.055	20%	0.198	C	C	.	.	H	α-helix	trans	-75.2	-23.6	175.9	-63.8	-94.5	0	0	0	112.9	I50 A51 I52 T59 A202 A205 E206 L310	I50-Y54 HydrophobicContact CG2-CE2 4.04Å; I50-Y54 WeakPolarHBondContact O-CD2 3.44Å; A51-Y54 PolarHBondContact O-N 2.9Å; I52-Y54 VanDerWaalsContact C-N 3.35Å; Y54-T59 HydrophobicContact CD1-CG2 4.37Å; Y54-A202 PolarHBondContact OH-O 3.46Å; Y54-A205 HydrophobicContact CD1-CB 4.02Å; Y54-A205 HydrophobicContact CD2-CB 3.57Å; Y54-A205 HydrophobicContact CE1-CB 4.06Å; Y54-A205 HydrophobicContact CE2-CB 3.64Å; Y54-A205 HydrophobicContact CG-CB 3.77Å; Y54-E206 HydrophobicContact CE1-CB 4.29Å; Y54-E206 WeakPolarHBondContact CE1-OE2 3.47Å; Y54-E206 PolarHBondContact OH-OE2 3.25Å; Y54-L310 HydrophobicContact CD1-CD1 4.16Å; Y54-L310 HydrophobicContact CE1-CB 3.98Å; Y54-L310 HydrophobicContact CE1-CD1 4Å; Y54-L310 HydrophobicContact CE2-CB 4.33Å; Y54-L310 WeakPolarHBondContact OH-CB 3.38Å; Y54-L310 PolarHBondContact OH-O 2.89Å
55	M	88.3	Confident	74.8	Confident	0 Å²	0	43.1 Å²	43.1	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-76.7	-34.4	176.2	-68.7	168.6	67.3	0	0	112.4	L48 A51 I52 L53 G74 E75 C76 W79 A133 L140 W210	L48-M55 HydrophobicContact CD1-SD 4.32Å; A51-M55 VanDerWaalsContact O-CG 3.27Å; A51-M55 WeakPolarHBondContact O-CG 3.38Å; A51-M55 PolarHBondContact O-N 3.41Å; I52-M55 HydrophobicContact CD1-CB 4.36Å; I52-M55 HydrophobicContact CD1-CE 4.2Å; I52-M55 HydrophobicContact CD1-SD 4.01Å; I52-M55 PolarHBondContact O-N 3.13Å; L53-M55 VanDerWaalsContact C-N 3.35Å; M55-G74 CarbonylContact O-C 3.57Å; M55-G74 WeakPolarHBondContact O-CA 3.19Å; M55-E75 PolarHBondContact O-N 3.4Å; M55-C76 HydrophobicContact CB-CB 4.28Å; M55-C76 CarbonylContact O-C 3.43Å; M55-C76 WeakPolarHBondContact O-CA 3.26Å; M55-C76 WeakPolarHBondContact O-CB 3.11Å; M55-C76 PolarHBondContact O-N 2.82Å; M55-W79 HydrophobicContact CE-CH2 3.92Å; M55-W79 HydrophobicContact CE-CZ3 4.06Å; M55-A133 HydrophobicContact CE-CB 3.91Å; M55-L140 HydrophobicContact CE-CD2 4.22Å; M55-W210 HydrophobicContact CE-CH2 4.03Å; M55-W210 HydrophobicContact CE-CZ2 4.48Å; M55-W210 HydrophobicContact CE-CZ3 4.12Å; M55-W210 HydrophobicContact CG-CD2 3.52Å; M55-W210 HydrophobicContact CG-CE3 3.74Å; M55-W210 HydrophobicContact CG-CG 3.91Å; M55-W210 HydrophobicContact CG-CH2 4.33Å; M55-W210 HydrophobicContact CG-CZ2 4.17Å; M55-W210 HydrophobicContact CG-CZ3 4.15Å; M55-W210 HydrophobicContact SD-CD2 4.27Å; M55-W210 HydrophobicContact SD-CE3 3.85Å; M55-W210 HydrophobicContact SD-CH2 4.32Å; M55-W210 HydrophobicContact SD-CZ3 3.88Å
56	T	85.7	Confident	72.7	Confident	33 Å²	33	44.8 Å²	44.8	20%	0.202	26%	0.258	C	S	.	.	H	α-helix	trans	-106.5	-22.4	-170.6	56.6	0	0	0	0	113.6	I52 V84	I52-T56 HydrophobicContact CD1-CG2 4.14Å; I52-T56 HydrophobicContact CG1-CG2 4.2Å; I52-T56 WeakPolarHBondContact O-CB 3.42Å; I52-T56 WeakPolarHBondContact O-CG2 3.35Å; I52-T56 PolarHBondContact O-N 2.82Å; I52-T56 PolarHBondContact O-OG1 3.29Å; T56-V84 HydrophobicContact CG2-CG2 3.94Å
57	T	77.8	Confident	70.5	Confident	35 Å²	35	55 Å²	55	22%	0.215	30%	0.302	C	S	.	.	S	Bend	trans	-98.5	134.1	-179	-46	0	0	0	0	110.1	L53 T59	L53-T57 WeakPolarHBondContact O-CB 3.46Å; L53-T57 PolarHBondContact O-N 3.42Å; L53-T57 PolarHBondContact O-OG1 2.94Å; T57-T59 PolarHBondContact O-N 3Å
58	N	67.6	Low	68	Low	99 Å²	99	61.1 Å²	61.1	53%	0.529	34%	0.335	S	S	.	.			trans	-67.2	120.9	170.4	-67.3	-17.7	0	0	0	109	G73 G74	N58-G73 WeakPolarHBondContact OD1-CA 3.27Å; N58-G74 PolarHBondContact OD1-N 3.24Å
59	T	61.2	Low	65.8	Low	32 Å²	32	63.7 Å²	63.7	20%	0.196	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107	128.7	-179.8	49.1	0	0	0	0	110.2	Y54 T57 R72 L310	Y54-T59 HydrophobicContact CD1-CG2 4.37Å; T57-T59 PolarHBondContact O-N 3Å; T59-R72 PolarHBondContact N-O 3.24Å; T59-R72 PolarHBondContact O-N 3.46Å; T59-R72 PolarHBondContact OG1-O 3.41Å; T59-L310 HydrophobicContact CG2-CD1 3.31Å
60	S	52.3	Low	63.5	Low	68 Å²	68	65.6 Å²	65.6	48%	0.476	37%	0.367	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.2	109	165	29.9	0	0	0	0	108.6	Q62	S60-Q62 PolarHBondContact O-N 3.32Å
61	R	50.9	Low	61.1	Low	75 Å²	75	74.5 Å²	74.5	28%	0.283	40%	0.4	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.4	111.7	169	-163.8	177.6	-168.7	-147.9	4.4	108.4	D63 V69 A70 H207	R61-D63 WeakPolarHBondContact CD-OD1 3.41Å; R61-D63 IonicContact CZ-OD1 2.84Å; R61-D63 IonicContact CZ-OD2 2.85Å; R61-D63 IonicContact NE-OD1 3.77Å; R61-D63 PolarHBondContact NE-OD1 2.89Å; R61-D63 IonicContact NE-OD2 3.04Å; R61-D63 VanDerWaalsContact NH1-CG 3.34Å; R61-D63 IonicContact NH1-OD1 2.86Å; R61-D63 PolarHBondContact NH1-OD1 3.05Å; R61-D63 IonicContact NH1-OD2 2.8Å; R61-D63 PolarHBondContact NH1-OD2 3.26Å; R61-D63 VanDerWaalsContact NH1-OD2 3.08Å; R61-D63 IonicContact NH2-OD1 3.15Å; R61-D63 PolarHBondContact O-N 3Å; R61-D63 VanDerWaalsContact O-N 3.07Å; R61-V69 VanDerWaalsContact O-CA 3.31Å; R61-V69 WeakPolarHBondContact O-CA 3.17Å; R61-A70 WeakPolarHBondContact CB-O 3.25Å; R61-A70 PolarHBondContact N-O 2.98Å; R61-A70 PolarHBondContact O-N 3.23Å; R61-H207 PolarHBondContact NH2-O 3.46Å
62	Q	46	Very low	59.3	Low	174 Å²	174	79.9 Å²	79.9	81%	0.813	42%	0.421	S	S	*	.			trans	-74	88.3	155.9	-94.9	-179	-27.6	0	0	106.7	S60 A64 V69	S60-Q62 PolarHBondContact O-N 3.32Å; Q62-A64 PolarHBondContact O-N 3.46Å; Q62-V69 HydrophobicContact CG-CG2 4.1Å
63	D	44.7	Very low	57.6	Low	42 Å²	42	81.5 Å²	81.5	23%	0.225	44%	0.439	C	S	.	.			trans	-63.9	110.6	170.1	-99	-37.6	0	0	0	107.5	R61 L65 A66	R61-D63 WeakPolarHBondContact CD-OD1 3.41Å; R61-D63 IonicContact CZ-OD1 2.84Å; R61-D63 IonicContact CZ-OD2 2.85Å; R61-D63 IonicContact NE-OD1 3.77Å; R61-D63 PolarHBondContact NE-OD1 2.89Å; R61-D63 IonicContact NE-OD2 3.04Å; R61-D63 VanDerWaalsContact NH1-CG 3.34Å; R61-D63 IonicContact NH1-OD1 2.86Å; R61-D63 PolarHBondContact NH1-OD1 3.05Å; R61-D63 IonicContact NH1-OD2 2.8Å; R61-D63 PolarHBondContact NH1-OD2 3.26Å; R61-D63 VanDerWaalsContact NH1-OD2 3.08Å; R61-D63 IonicContact NH2-OD1 3.15Å; R61-D63 PolarHBondContact O-N 3Å; R61-D63 VanDerWaalsContact O-N 3.07Å; D63-L65 PolarHBondContact O-N 2.9Å; D63-A66 HydrophobicContact CB-CB 3.63Å; D63-A66 CarbonylContact O-C 2.79Å; D63-A66 PolarHBondContact O-N 2.95Å
64	A	48.1	Very low	56.5	Low	113 Å²	113	81.5 Å²	81.5	93%	0.934	44%	0.44	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.1	-16.9	178.7	0	0	0	0	0	112.9	Q62	Q62-A64 PolarHBondContact O-N 3.46Å
65	L	47.9	Very low	55.9	Low	181 Å²	181	84.6 Å²	84.6	95%	0.948	46%	0.455	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.4	-20.2	176.8	-132.2	82.8	0	0	0	114.4	D63	D63-L65 PolarHBondContact O-N 2.9Å
66	A	45.2	Very low	55.6	Low	46 Å²	46	84.8 Å²	84.8	38%	0.38	46%	0.457	S	S	.	.			trans	-110.6	117.1	179	0	0	0	0	0	108.2	D63 D68	D63-A66 HydrophobicContact CB-CB 3.63Å; D63-A66 CarbonylContact O-C 2.79Å; D63-A66 PolarHBondContact O-N 2.95Å; A66-D68 PolarHBondContact O-N 2.89Å
67	K	44.5	Very low	55.1	Low	217 Å²	217	86.5 Å²	86.5	94%	0.943	47%	0.47	S	S	*	.	S	Bend	trans	-57.8	-13.3	175.2	-82.5	-178.3	173.9	178.9	0	113.3
68	D	37.1	Very low	55.4	Low	133 Å²	133	90.8 Å²	90.8	71%	0.711	49%	0.492	S	S	*	.	S	Bend	trans	-100	127.4	176.8	-62.9	-40.5	0	0	0	111.4	A66 A70	A66-D68 PolarHBondContact O-N 2.89Å; D68-A70 PolarHBondContact O-N 2.86Å
69	V	45.4	Very low	56.4	Low	56 Å²	56	87.4 Å²	87.4	34%	0.339	47%	0.471	S	S	.	.			trans	-66	99.7	171.3	178.2	0	0	0	0	108	R61 Q62 W71	R61-V69 VanDerWaalsContact O-CA 3.31Å; R61-V69 WeakPolarHBondContact O-CA 3.17Å; Q62-V69 HydrophobicContact CG-CG2 4.1Å; V69-W71 HydrophobicContact CG1-CD2 4.36Å; V69-W71 HydrophobicContact CG1-CZ2 4.34Å; V69-W71 PolarHBondContact O-N 2.98Å; V69-W71 VanDerWaalsContact O-N 3.08Å
70	A	41.3	Very low	57.8	Low	46 Å²	46	90.4 Å²	90.4	38%	0.38	49%	0.486	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.2	102.9	172.3	0	0	0	0	0	108.4	R61 D68 R72	R61-A70 WeakPolarHBondContact CB-O 3.25Å; R61-A70 PolarHBondContact N-O 2.98Å; R61-A70 PolarHBondContact O-N 3.23Å; D68-A70 PolarHBondContact O-N 2.86Å; A70-R72 PolarHBondContact O-N 3.29Å; A70-R72 VanDerWaalsContact O-N 3.15Å
71	W	41.2	Very low	59.6	Low	187 Å²	187	88.9 Å²	88.9	71%	0.708	48%	0.476	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-69	107.1	172.4	-64.7	94.3	0	0	0	109	V69 G73	V69-W71 HydrophobicContact CG1-CD2 4.36Å; V69-W71 HydrophobicContact CG1-CZ2 4.34Å; V69-W71 PolarHBondContact O-N 2.98Å; V69-W71 VanDerWaalsContact O-N 3.08Å; W71-G73 PolarHBondContact O-N 3.28Å
72	R	52.7	Low	61.6	Low	114 Å²	114	88.3 Å²	88.3	43%	0.43	48%	0.48	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.4	99.8	162.9	-80.5	-170.9	176.9	168	0.5	107	T59 A70 G74 S208 H209	T59-R72 PolarHBondContact N-O 3.24Å; T59-R72 PolarHBondContact O-N 3.46Å; T59-R72 PolarHBondContact OG1-O 3.41Å; A70-R72 PolarHBondContact O-N 3.29Å; A70-R72 VanDerWaalsContact O-N 3.15Å; R72-G74 PolarHBondContact O-N 3.29Å; R72-S208 PolarHBondContact NH1-O 3.11Å; R72-H209 PolarHBondContact NH1-CD2 3.38Å
73	G	55.6	Low	63.8	Low	41 Å²	41	81.1 Å²	81.1	42%	0.423	45%	0.448	S	S	.	.			trans	-55	138.8	163.7	0	0	0	0	0	109.2	N58 W71 E75	N58-G73 WeakPolarHBondContact OD1-CA 3.27Å; W71-G73 PolarHBondContact O-N 3.28Å; G73-E75 PolarHBondContact O-N 2.8Å
74	G	65.5	Low	66.1	Low	5 Å²	5	80 Å²	80	5%	0.052	44%	0.443	C	S	.	.			trans	-57.6	117.2	174.5	0	0	0	0	0	108	M55 N58 R72 C76 S77	M55-G74 CarbonylContact O-C 3.57Å; M55-G74 WeakPolarHBondContact O-CA 3.19Å; N58-G74 PolarHBondContact OD1-N 3.24Å; R72-G74 PolarHBondContact O-N 3.29Å; G74-C76 PolarHBondContact O-N 2.92Å; G74-S77 VanDerWaalsContact O-CB 3.3Å; G74-S77 WeakPolarHBondContact O-CB 3.41Å; G74-S77 PolarHBondContact O-N 3.33Å; G74-S77 PolarHBondContact O-OG 3.45Å
75	E	75.4	Confident	68.2	Low	79 Å²	79	74.7 Å²	74.7	37%	0.369	40%	0.399	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.7	-17.6	-177	-69.7	-172.5	-149.8	0	0	113	M55 G73 R134 H209	M55-E75 PolarHBondContact O-N 3.4Å; G73-E75 PolarHBondContact O-N 2.8Å; E75-R134 IonicContact OE2-CZ 2.82Å; E75-R134 IonicContact OE2-NH1 3.62Å; E75-R134 PolarHBondContact OE2-NH1 2.58Å; E75-H209 IonicContact OE1-CE1 3.95Å; E75-H209 IonicContact OE1-NE2 3.36Å; E75-H209 PolarHBondContact OE1-NE2 2.85Å
76	C	80.6	Confident	70.4	Confident	5 Å²	5	67.1 Å²	67.1	3%	0.034	36%	0.362	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.9	28	-179.9	-52.9	0	0	0	0	111.9	M55 G74 D78 W79	M55-C76 HydrophobicContact CB-CB 4.28Å; M55-C76 CarbonylContact O-C 3.43Å; M55-C76 WeakPolarHBondContact O-CA 3.26Å; M55-C76 WeakPolarHBondContact O-CB 3.11Å; M55-C76 PolarHBondContact O-N 2.82Å; G74-C76 PolarHBondContact O-N 2.92Å; C76-D78 WeakPolarHBondContact CA-OD1 3.42Å; C76-D78 PolarHBondContact O-N 3.35Å; C76-W79 HydrophobicContact CB-CD2 3.71Å; C76-W79 HydrophobicContact CB-CE3 4.06Å; C76-W79 HydrophobicContact CB-CG 4.13Å; C76-W79 HydrophobicContact CB-CH2 4.19Å; C76-W79 HydrophobicContact CB-CZ2 3.86Å; C76-W79 HydrophobicContact CB-CZ3 4.28Å; C76-W79 WeakPolarHBondContact O-CB 3.13Å; C76-W79 PolarHBondContact O-N 3.31Å; C76-W79 VanDerWaalsContact SG-CZ2 3.58Å
77	S	77.1	Confident	72.7	Confident	68 Å²	68	64.9 Å²	64.9	48%	0.476	34%	0.344	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66	-16.5	179.9	64.6	0	0	0	0	113.7	G74 W79	G74-S77 VanDerWaalsContact O-CB 3.3Å; G74-S77 WeakPolarHBondContact O-CB 3.41Å; G74-S77 PolarHBondContact O-N 3.33Å; G74-S77 PolarHBondContact O-OG 3.45Å; S77-W79 VanDerWaalsContact C-N 3.26Å
78	D	84	Confident	75	Confident	126 Å²	126	54.9 Å²	54.9	67%	0.674	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.6	-11.5	176	63.8	-42.4	0	0	0	113.2	C76 N80	C76-D78 WeakPolarHBondContact CA-OD1 3.42Å; C76-D78 PolarHBondContact O-N 3.35Å; D78-N80 PolarHBondContact O-N 2.93Å
79	W	88.5	Confident	77.6	Confident	27 Å²	27	48.5 Å²	48.5	10%	0.102	27%	0.267	C	S	.	.			trans	-74.6	126.9	-178.7	-66.1	8.6	0	0	0	111.4	I52 M55 C76 S77 T83 V84 V87 A133 P137 L140	I52-W79 HydrophobicContact CD1-CE3 4.38Å; I52-W79 HydrophobicContact CD1-CZ3 4.06Å; M55-W79 HydrophobicContact CE-CH2 3.92Å; M55-W79 HydrophobicContact CE-CZ3 4.06Å; C76-W79 HydrophobicContact CB-CD2 3.71Å; C76-W79 HydrophobicContact CB-CE3 4.06Å; C76-W79 HydrophobicContact CB-CG 4.13Å; C76-W79 HydrophobicContact CB-CH2 4.19Å; C76-W79 HydrophobicContact CB-CZ2 3.86Å; C76-W79 HydrophobicContact CB-CZ3 4.28Å; C76-W79 WeakPolarHBondContact O-CB 3.13Å; C76-W79 PolarHBondContact O-N 3.31Å; C76-W79 VanDerWaalsContact SG-CZ2 3.58Å; S77-W79 VanDerWaalsContact C-N 3.26Å; W79-T83 HydrophobicContact CG-CG2 4.45Å; W79-V84 HydrophobicContact CB-CG2 4.11Å; W79-V87 HydrophobicContact CE3-CG2 4.44Å; W79-V87 HydrophobicContact CZ3-CG1 4.41Å; W79-V87 HydrophobicContact CZ3-CG2 3.98Å; W79-A133 HydrophobicContact CH2-CB 4.47Å; W79-P137 HydrophobicContact CD2-CB 4.06Å; W79-P137 HydrophobicContact CE3-CB 4.47Å; W79-P137 HydrophobicContact CH2-CB 4.32Å; W79-P137 HydrophobicContact CZ2-CB 3.88Å; W79-L140 HydrophobicContact CH2-CD2 3.7Å; W79-L140 HydrophobicContact CZ3-CD2 4.04Å
80	N	90.1	Very high	79.8	Confident	96 Å²	96	45.9 Å²	45.9	51%	0.513	25%	0.251	S	S	.	.			trans	-69.8	158.4	172.9	69.7	28	0	0	0	112.1	D78 V82 T83 V84	D78-N80 PolarHBondContact O-N 2.93Å; N80-V82 PolarHBondContact O-N 3.28Å; N80-V82 VanDerWaalsContact O-N 3.16Å; N80-V82 PolarHBondContact OD1-N 3.11Å; N80-T83 WeakPolarHBondContact O-CB 3.36Å; N80-T83 PolarHBondContact O-N 2.93Å; N80-T83 WeakPolarHBondContact OD1-CB 3.29Å; N80-T83 PolarHBondContact OD1-N 2.61Å; N80-T83 PolarHBondContact OD1-OG1 2.84Å; N80-V84 PolarHBondContact O-N 2.91Å
81	S	89.3	Confident	82.1	Confident	36 Å²	36	43.7 Å²	43.7	25%	0.252	23%	0.233	S	C	.	.	H	α-helix	trans	-57.5	-32.9	-177.2	-56.7	0	0	0	0	113.9	V84 G85 G441 V444	S81-V84 PolarHBondContact O-N 2.97Å; S81-G85 PolarHBondContact O-N 3.41Å; S81-G441 CarbonylContact C-O 3.47Å; S81-G441 WeakPolarHBondContact CB-O 3.06Å; S81-G441 VanDerWaalsContact O-CA 3.26Å; S81-G441 WeakPolarHBondContact O-CA 3.48Å; S81-V444 WeakPolarHBondContact CB-O 3.49Å; S81-V444 PolarHBondContact OG-O 3.03Å
82	V	92.5	Very high	84.4	Confident	63 Å²	63	35.1 Å²	35.1	38%	0.382	20%	0.2	S	C	.	.	H	α-helix	trans	-67.7	-40.1	176.9	178.8	0	0	0	0	111.2	N80 G85 A86 G441 A442	N80-V82 PolarHBondContact O-N 3.28Å; N80-V82 VanDerWaalsContact O-N 3.16Å; N80-V82 PolarHBondContact OD1-N 3.11Å; V82-G85 PolarHBondContact O-N 3Å; V82-A86 WeakPolarHBondContact O-CB 3.42Å; V82-A86 PolarHBondContact O-N 3.22Å; V82-G441 PolarHBondContact N-O 2.96Å; V82-A442 HydrophobicContact CG2-CB 4.44Å
83	T	93.3	Very high	86.1	Confident	23 Å²	23	34 Å²	34	14%	0.141	20%	0.197	C	C	.	.	H	α-helix	trans	-67.1	-41.9	177.2	-59.6	0	0	0	0	110.6	W79 N80 G85 A86 V87 P137	W79-T83 HydrophobicContact CG-CG2 4.45Å; N80-T83 WeakPolarHBondContact O-CB 3.36Å; N80-T83 PolarHBondContact O-N 2.93Å; N80-T83 WeakPolarHBondContact OD1-CB 3.29Å; N80-T83 PolarHBondContact OD1-N 2.61Å; N80-T83 PolarHBondContact OD1-OG1 2.84Å; T83-G85 VanDerWaalsContact C-N 3.34Å; T83-G85 PolarHBondContact O-N 3.43Å; T83-A86 WeakPolarHBondContact O-CB 3.39Å; T83-A86 PolarHBondContact O-N 3.46Å; T83-V87 WeakPolarHBondContact O-CB 3.45Å; T83-V87 WeakPolarHBondContact O-CG2 3.4Å; T83-V87 PolarHBondContact O-N 2.91Å; T83-P137 HydrophobicContact CG2-CB 3.37Å; T83-P137 HydrophobicContact CG2-CG 3.93Å
84	V	92	Very high	87.5	Confident	19 Å²	19	32 Å²	32	12%	0.115	18%	0.177	C	C	.	.	H	α-helix	trans	-58.8	-46.1	172.8	173.7	0	0	0	0	110.8	I52 T56 W79 N80 S81 A86 V87 L88	I52-V84 HydrophobicContact CD1-CG1 4.49Å; I52-V84 HydrophobicContact CG1-CG1 3.8Å; T56-V84 HydrophobicContact CG2-CG2 3.94Å; W79-V84 HydrophobicContact CB-CG2 4.11Å; N80-V84 PolarHBondContact O-N 2.91Å; S81-V84 PolarHBondContact O-N 2.97Å; V84-A86 PolarHBondContact O-N 3.15Å; V84-V87 PolarHBondContact O-N 2.89Å; V84-L88 HydrophobicContact CG1-CD1 4.1Å; V84-L88 WeakPolarHBondContact O-CG 3.43Å; V84-L88 PolarHBondContact O-N 3.48Å
85	G	92.4	Very high	88.4	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-60.7	-41.9	174.6	0	0	0	0	0	113.1	S81 V82 T83 L88 G89 Y297 P437	S81-G85 PolarHBondContact O-N 3.41Å; V82-G85 PolarHBondContact O-N 3Å; T83-G85 VanDerWaalsContact C-N 3.34Å; T83-G85 PolarHBondContact O-N 3.43Å; G85-L88 PolarHBondContact O-N 3Å; G85-G89 PolarHBondContact O-N 2.8Å; G85-Y297 WeakPolarHBondContact CA-OH 3.41Å; G85-Y297 PolarHBondContact N-OH 3.23Å; G85-P437 VanDerWaalsContact CA-O 3.32Å; G85-P437 WeakPolarHBondContact CA-O 3.47Å; G85-P437 VanDerWaalsContact O-CB 3.28Å; G85-P437 WeakPolarHBondContact O-CB 3.43Å
86	A	94.5	Very high	88.8	Confident	22 Å²	22	30 Å²	30	18%	0.182	17%	0.167	C	C	.	.	H	α-helix	trans	-63.5	-42.5	175.9	0	0	0	0	0	111.8	V82 T83 V84 G89 S90 I141 L438	V82-A86 WeakPolarHBondContact O-CB 3.42Å; V82-A86 PolarHBondContact O-N 3.22Å; T83-A86 WeakPolarHBondContact O-CB 3.39Å; T83-A86 PolarHBondContact O-N 3.46Å; V84-A86 PolarHBondContact O-N 3.15Å; A86-G89 PolarHBondContact O-N 3.34Å; A86-S90 WeakPolarHBondContact O-CA 3.44Å; A86-S90 WeakPolarHBondContact O-CB 3.28Å; A86-S90 PolarHBondContact O-N 3.19Å; A86-I141 HydrophobicContact CB-CD1 3.89Å; A86-L438 HydrophobicContact CB-CD2 3.77Å
87	V	94.3	Very high	88.7	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-61.8	-44.7	175.3	164.4	0	0	0	0	111.2	L48 I52 W79 T83 V84 S90 L140 I141	L48-V87 HydrophobicContact CD1-CG1 4.46Å; L48-V87 HydrophobicContact CD2-CG1 3.87Å; I52-V87 HydrophobicContact CD1-CG1 4.48Å; W79-V87 HydrophobicContact CE3-CG2 4.44Å; W79-V87 HydrophobicContact CZ3-CG1 4.41Å; W79-V87 HydrophobicContact CZ3-CG2 3.98Å; T83-V87 WeakPolarHBondContact O-CB 3.45Å; T83-V87 WeakPolarHBondContact O-CG2 3.4Å; T83-V87 PolarHBondContact O-N 2.91Å; V84-V87 PolarHBondContact O-N 2.89Å; V87-S90 PolarHBondContact O-OG 3.4Å; V87-L140 HydrophobicContact CG1-CD2 3.62Å; V87-L140 HydrophobicContact CG1-CG 4.14Å; V87-L140 HydrophobicContact CG2-CD2 4.35Å; V87-I141 HydrophobicContact CB-CG1 4.47Å; V87-I141 HydrophobicContact CG2-CD1 4.16Å; V87-I141 HydrophobicContact CG2-CG1 3.7Å
88	L	91.7	Very high	88.5	Confident	6 Å²	6	31.8 Å²	31.8	3%	0.031	17%	0.174	C	C	.	.	H	α-helix	trans	-65.5	-43.2	177.6	-72.6	167.9	0	0	0	112.3	L48 I52 V84 G85 T296 Y297 P437	L48-L88 HydrophobicContact CD2-CD2 4.35Å; L48-L88 HydrophobicContact CG-CD2 4.07Å; I52-L88 HydrophobicContact CG2-CD2 4.29Å; V84-L88 HydrophobicContact CG1-CD1 4.1Å; V84-L88 WeakPolarHBondContact O-CG 3.43Å; V84-L88 PolarHBondContact O-N 3.48Å; G85-L88 PolarHBondContact O-N 3Å; L88-T296 HydrophobicContact CB-CG2 4.47Å; L88-Y297 HydrophobicContact CD1-CD2 4.39Å; L88-Y297 HydrophobicContact CD1-CE1 4.18Å; L88-Y297 HydrophobicContact CD1-CE2 3.8Å; L88-P437 HydrophobicContact CB-CB 4.24Å
89	G	91.4	Very high	87.8	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-78	-23.8	-179.1	0	0	0	0	0	115.1	G85 A86 F91 F92 Y93	G85-G89 PolarHBondContact O-N 2.8Å; A86-G89 PolarHBondContact O-N 3.34Å; G89-F91 PolarHBondContact O-N 2.68Å; G89-F92 WeakPolarHBondContact O-CB 3.14Å; G89-F92 PolarHBondContact O-N 3.35Å; G89-Y93 WeakPolarHBondContact O-CD2 3.26Å
90	S	92.7	Very high	86.7	Confident	1 Å²	1	31.1 Å²	31.1	1%	0.007	17%	0.171	C	C	.	.	H	α-helix	trans	-52.9	-33.2	-173.7	59.2	0	0	0	0	114.7	A86 V87 F92 Y93 R144 V145	A86-S90 WeakPolarHBondContact O-CA 3.44Å; A86-S90 WeakPolarHBondContact O-CB 3.28Å; A86-S90 PolarHBondContact O-N 3.19Å; V87-S90 PolarHBondContact O-OG 3.4Å; S90-F92 VanDerWaalsContact C-N 3.26Å; S90-F92 PolarHBondContact O-N 3.03Å; S90-Y93 WeakPolarHBondContact O-CB 3.3Å; S90-Y93 PolarHBondContact O-N 3.14Å; S90-R144 WeakPolarHBondContact OG-CB 3.41Å; S90-V145 WeakPolarHBondContact O-CG2 3.33Å
91	F	90.3	Very high	85.3	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-57.4	-39	175.4	176.7	-87.5	0	0	0	112.8	R45 G89 Y93 G94 Y95 Q147 G148 Q151	R45-F91 HydrophobicContact CG-CD1 4.29Å; R45-F91 HydrophobicContact CG-CE1 4.18Å; G89-F91 PolarHBondContact O-N 2.68Å; F91-Y93 VanDerWaalsContact C-N 3.32Å; F91-Y93 PolarHBondContact O-N 3.43Å; F91-G94 PolarHBondContact O-N 2.95Å; F91-Y95 HydrophobicContact CE1-CD2 4.33Å; F91-Y95 HydrophobicContact CE1-CG 4.28Å; F91-Y95 HydrophobicContact CZ-CD2 4.5Å; F91-Y95 PolarHBondContact O-N 3.47Å; F91-Y95 VanDerWaalsContact O-N 3.11Å; F91-Q147 HydrophobicContact CD2-CB 4.24Å; F91-Q147 HydrophobicContact CE2-CB 4.39Å; F91-G148 VanDerWaalsContact CE2-CA 3.42Å; F91-G148 WeakPolarHBondContact O-CA 3.29Å; F91-Q151 HydrophobicContact CE2-CB 4.49Å; F91-Q151 HydrophobicContact CE2-CG 4.07Å; F91-Q151 HydrophobicContact CZ-CB 4.11Å; F91-Q151 VanDerWaalsContact CZ-CD 3.44Å; F91-Q151 HydrophobicContact CZ-CG 4.04Å
92	F	88.8	Confident	83.8	Confident	6 Å²	6	28.5 Å²	28.5	3%	0.026	16%	0.159	C	C	.	.	H	α-helix	trans	-72.3	-25.8	-175.9	-67.4	-78.4	0	0	0	113	G89 S90 Y95 L96 Y292 T430 G433 M434	G89-F92 WeakPolarHBondContact O-CB 3.14Å; G89-F92 PolarHBondContact O-N 3.35Å; S90-F92 VanDerWaalsContact C-N 3.26Å; S90-F92 PolarHBondContact O-N 3.03Å; F92-Y95 PolarHBondContact O-N 2.88Å; F92-L96 WeakPolarHBondContact O-CB 3.5Å; F92-L96 PolarHBondContact O-N 2.87Å; F92-Y292 AromaticContact CE1-CD1 3.81Å; F92-Y292 HydrophobicContact CE1-CD1 3.81Å; F92-Y292 HydrophobicContact CE1-CD2 4.37Å; F92-Y292 AromaticContact CE1-CE1 3.42Å; F92-Y292 HydrophobicContact CE1-CE1 3.42Å; F92-Y292 VanDerWaalsContact CE1-CE1 3.42Å; F92-Y292 HydrophobicContact CE1-CE2 4.03Å; F92-Y292 HydrophobicContact CE1-CG 4.28Å; F92-Y292 AromaticContact CE1-CZ 3.55Å; F92-Y292 HydrophobicContact CE2-CD1 4.44Å; F92-Y292 AromaticContact CZ-CD1 3.45Å; F92-Y292 HydrophobicContact CZ-CD1 3.45Å; F92-Y292 VanDerWaalsContact CZ-CD1 3.45Å; F92-Y292 HydrophobicContact CZ-CD2 4.46Å; F92-Y292 AromaticContact CZ-CE1 3.54Å; F92-Y292 HydrophobicContact CZ-CE1 3.54Å; F92-Y292 AromaticContact CZ-CG 3.96Å; F92-Y292 HydrophobicContact CZ-CG 3.96Å; F92-T430 HydrophobicContact CB-CG2 4.41Å; F92-T430 HydrophobicContact CD1-CG2 4.12Å; F92-G433 VanDerWaalsContact CD2-C 3.43Å; F92-G433 WeakPolarHBondContact CD2-O 3.4Å; F92-M434 HydrophobicContact CB-CG 3.55Å
93	Y	88.9	Confident	81.9	Confident	90 Å²	90	27.4 Å²	27.4	35%	0.353	16%	0.161	S	C	.	.	H	α-helix	trans	-60.3	-48.2	173.5	-69.4	-101.3	0	0	0	110.8	G89 S90 F91 V97 M434 L438	G89-Y93 WeakPolarHBondContact O-CD2 3.26Å; S90-Y93 WeakPolarHBondContact O-CB 3.3Å; S90-Y93 PolarHBondContact O-N 3.14Å; F91-Y93 VanDerWaalsContact C-N 3.32Å; F91-Y93 PolarHBondContact O-N 3.43Å; Y93-V97 WeakPolarHBondContact O-CG2 3.32Å; Y93-V97 PolarHBondContact O-N 2.88Å; Y93-M434 HydrophobicContact CD1-CE 3.51Å; Y93-M434 HydrophobicContact CD2-CE 4.46Å; Y93-M434 HydrophobicContact CD2-CG 4.04Å; Y93-M434 HydrophobicContact CE1-CE 3.53Å; Y93-M434 HydrophobicContact CE2-CB 4.07Å; Y93-M434 HydrophobicContact CE2-CG 4.11Å; Y93-M434 HydrophobicContact CG-CE 3.99Å; Y93-M434 HydrophobicContact CG-CG 4.35Å; Y93-L438 VanDerWaalsContact OH-CD1 3.27Å; Y93-L438 WeakPolarHBondContact OH-CD1 3.19Å
94	G	84.9	Confident	79.9	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-65.1	-43.8	175.8	0	0	0	0	0	112.1	F91 L96 T98 V145 L149	F91-G94 PolarHBondContact O-N 2.95Å; G94-L96 VanDerWaalsContact C-N 3.33Å; G94-L96 PolarHBondContact O-N 2.73Å; G94-T98 PolarHBondContact O-OG1 3.3Å; G94-V145 WeakPolarHBondContact CA-O 3.39Å; G94-L149 WeakPolarHBondContact O-CD2 3.45Å
95	Y	82.9	Confident	77.9	Confident	9 Å²	9	35 Å²	35	4%	0.035	19%	0.187	C	C	.	.	H	α-helix	trans	-62.7	-36.7	-179.6	-172.1	-109	0	0	0	113.2	F91 F92 T98 Q99 A152 T430	F91-Y95 HydrophobicContact CE1-CD2 4.33Å; F91-Y95 HydrophobicContact CE1-CG 4.28Å; F91-Y95 HydrophobicContact CZ-CD2 4.5Å; F91-Y95 PolarHBondContact O-N 3.47Å; F91-Y95 VanDerWaalsContact O-N 3.11Å; F92-Y95 PolarHBondContact O-N 2.88Å; Y95-T98 VanDerWaalsContact C-OG1 3.27Å; Y95-T98 PolarHBondContact O-OG1 3.22Å; Y95-Q99 HydrophobicContact CE1-CG 4.45Å; Y95-Q99 WeakPolarHBondContact O-CG 3.35Å; Y95-Q99 PolarHBondContact O-N 3.25Å; Y95-Q99 PolarHBondContact OH-NE2 2.88Å; Y95-Q99 VanDerWaalsContact OH-NE2 3.11Å; Y95-A152 HydrophobicContact CD2-CB 3.65Å; Y95-A152 HydrophobicContact CE2-CB 4.02Å; Y95-T430 HydrophobicContact CD1-CG2 3.72Å; Y95-T430 HydrophobicContact CE1-CG2 4.38Å
96	L	83.7	Confident	76	Confident	34 Å²	34	35.2 Å²	35.2	18%	0.178	19%	0.189	C	C	.	.	H	α-helix	trans	-65.3	-50	-179.7	179.9	70.8	0	0	0	112.4	F92 G94 T98 Q99 T427 T430 L431 M434	F92-L96 WeakPolarHBondContact O-CB 3.5Å; F92-L96 PolarHBondContact O-N 2.87Å; G94-L96 VanDerWaalsContact C-N 3.33Å; G94-L96 PolarHBondContact O-N 2.73Å; L96-T98 PolarHBondContact O-N 3.4Å; L96-Q99 WeakPolarHBondContact O-CB 3.49Å; L96-Q99 PolarHBondContact O-N 3.13Å; L96-T427 HydrophobicContact CD1-CG2 3.7Å; L96-T427 WeakPolarHBondContact CD1-O 3.42Å; L96-T430 HydrophobicContact CB-CG2 4.16Å; L96-T430 HydrophobicContact CD1-CG2 4.23Å; L96-L431 HydrophobicContact CD1-CD2 4.42Å; L96-L431 HydrophobicContact CD2-CD2 3.76Å; L96-M434 HydrophobicContact CB-SD 4.2Å; L96-M434 HydrophobicContact CD2-CE 4.15Å; L96-M434 HydrophobicContact CD2-SD 3.66Å; L96-M434 HydrophobicContact CG-SD 4.49Å
97	V	79.7	Confident	74.2	Confident	100 Å²	100	39.1 Å²	39.1	61%	0.606	21%	0.214	S	C	*	.	H	α-helix	trans	-51.9	-33.5	-177.2	169.8	0	0	0	0	111.5	Y93 P101 L149	Y93-V97 WeakPolarHBondContact O-CG2 3.32Å; Y93-V97 PolarHBondContact O-N 2.88Å; V97-P101 VanDerWaalsContact O-CD 3.32Å; V97-P101 WeakPolarHBondContact O-CD 3.39Å; V97-L149 HydrophobicContact CB-CD2 4.11Å; V97-L149 HydrophobicContact CG1-CD2 4.19Å
98	T	71.9	Confident	72.4	Confident	9 Å²	9	46.2 Å²	46.2	6%	0.055	24%	0.244	C	C	.	.	H	α-helix	trans	-89.3	-14.8	-175.3	40.1	0	0	0	0	115.1	G94 Y95 L96 L100 P101 S102 L149 A152 R153 P161	G94-T98 PolarHBondContact O-OG1 3.3Å; Y95-T98 VanDerWaalsContact C-OG1 3.27Å; Y95-T98 PolarHBondContact O-OG1 3.22Å; L96-T98 PolarHBondContact O-N 3.4Å; T98-L100 VanDerWaalsContact C-N 3.32Å; T98-L100 PolarHBondContact O-N 3.49Å; T98-P101 WeakPolarHBondContact O-CD 3.45Å; T98-S102 VanDerWaalsContact O-CB 3.25Å; T98-S102 WeakPolarHBondContact O-CB 3.16Å; T98-S102 PolarHBondContact O-N 3.43Å; T98-L149 HydrophobicContact CG2-CD2 3.83Å; T98-A152 WeakPolarHBondContact CB-O 3.4Å; T98-A152 HydrophobicContact CG2-CB 4.17Å; T98-A152 WeakPolarHBondContact CG2-O 3.34Å; T98-A152 WeakPolarHBondContact OG1-CB 3.21Å; T98-R153 WeakPolarHBondContact CG2-O 3.47Å; T98-P161 WeakPolarHBondContact O-CG 3.35Å
99	Q	70.6	Confident	70.9	Confident	14 Å²	14	48.4 Å²	48.4	7%	0.065	26%	0.258	C	S	.	.	H	α-helix	trans	-65.1	-30.3	-178.8	-77.5	-58.7	-27.8	0	0	114.1	Y95 L96 S102 N426	Y95-Q99 HydrophobicContact CE1-CG 4.45Å; Y95-Q99 WeakPolarHBondContact O-CG 3.35Å; Y95-Q99 PolarHBondContact O-N 3.25Å; Y95-Q99 PolarHBondContact OH-NE2 2.88Å; Y95-Q99 VanDerWaalsContact OH-NE2 3.11Å; L96-Q99 WeakPolarHBondContact O-CB 3.49Å; L96-Q99 PolarHBondContact O-N 3.13Å; Q99-S102 VanDerWaalsContact C-CB 3.4Å; Q99-S102 WeakPolarHBondContact O-CB 3.41Å; Q99-S102 PolarHBondContact O-OG 3.33Å; Q99-N426 PolarHBondContact NE2-ND2 3.21Å; Q99-N426 PolarHBondContact OE1-ND2 3.43Å
100	L	65.6	Low	69.5	Low	125 Å²	125	49.3 Å²	49.3	65%	0.654	27%	0.267	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.3	-50	-177.5	-67	168	0	0	0	113	T98 S102 T427	T98-L100 VanDerWaalsContact C-N 3.32Å; T98-L100 PolarHBondContact O-N 3.49Å; L100-S102 VanDerWaalsContact C-N 3.29Å; L100-S102 PolarHBondContact O-N 2.92Å; L100-T427 HydrophobicContact CD1-CG2 4.33Å; L100-T427 HydrophobicContact CD2-CG2 4.21Å; L100-T427 HydrophobicContact CG-CG2 4.11Å
101	P	60.3	Low	68.4	Low	65 Å²	65	49.5 Å²	49.5	42%	0.422	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68	-33.4	-179.3	-19.2	33.7	0	0	0	112.6	V97 T98 G103 W104 L105	V97-P101 VanDerWaalsContact O-CD 3.32Å; V97-P101 WeakPolarHBondContact O-CD 3.39Å; T98-P101 WeakPolarHBondContact O-CD 3.45Å; P101-G103 PolarHBondContact O-N 2.9Å; P101-W104 PolarHBondContact O-N 3.3Å; P101-L105 HydrophobicContact CB-CD1 3.73Å; P101-L105 WeakPolarHBondContact O-CD1 3.38Å; P101-L105 PolarHBondContact O-N 3.03Å
102	S	57.7	Low	68	Low	12 Å²	12	51.3 Å²	51.3	8%	0.084	28%	0.276	C	S	.	.	H	α-helix	trans	4.2	-83.1	157.1	172.4	0	0	0	0	119.9	T98 Q99 L100 A106 P161 P164	T98-S102 VanDerWaalsContact O-CB 3.25Å; T98-S102 WeakPolarHBondContact O-CB 3.16Å; T98-S102 PolarHBondContact O-N 3.43Å; Q99-S102 VanDerWaalsContact C-CB 3.4Å; Q99-S102 WeakPolarHBondContact O-CB 3.41Å; Q99-S102 PolarHBondContact O-OG 3.33Å; L100-S102 VanDerWaalsContact C-N 3.29Å; L100-S102 PolarHBondContact O-N 2.92Å; S102-A106 PolarHBondContact O-N 3.23Å; S102-P161 VanDerWaalsContact CA-CG 3.43Å; S102-P161 VanDerWaalsContact CB-CG 3.45Å; S102-P164 WeakPolarHBondContact OG-CG 3.45Å
103	G	51.9	Low	67.5	Low	41 Å²	41	57 Å²	57	42%	0.423	30%	0.297	S	S	.	.	H	α-helix	trans	-71.4	-36.4	-169.7	0	0	0	0	0	112.4	P101	P101-G103 PolarHBondContact O-N 2.9Å
104	W	52.1	Low	66.8	Low	173 Å²	173	52.8 Å²	52.8	66%	0.655	28%	0.281	S	S	*	.	H	α-helix	trans	-67.8	-44.8	-178	178.8	77.4	0	0	0	111.8	P101 K108	P101-W104 PolarHBondContact O-N 3.3Å; W104-K108 HydrophobicContact CH2-CD 4.46Å; W104-K108 VanDerWaalsContact CH2-NZ 3.31Å
105	L	50.1	Low	66.6	Low	29 Å²	29	52.8 Å²	52.8	15%	0.152	28%	0.281	C	S	.	.	H	α-helix	trans	-72.5	-31.4	-179.1	-75	91.1	0	0	0	111.9	P101 C107 K108 K158 P160	P101-L105 HydrophobicContact CB-CD1 3.73Å; P101-L105 WeakPolarHBondContact O-CD1 3.38Å; P101-L105 PolarHBondContact O-N 3.03Å; L105-C107 PolarHBondContact O-N 2.65Å; L105-C107 VanDerWaalsContact O-N 3.14Å; L105-K108 PolarHBondContact O-N 2.84Å; L105-K158 HydrophobicContact CD2-CB 4.41Å; L105-K158 WeakPolarHBondContact CD2-O 3.03Å; L105-P160 HydrophobicContact CB-CB 3.78Å; L105-P160 HydrophobicContact CB-CG 3.52Å
106	A	52.6	Low	66.8	Low	4 Å²	4	52.4 Å²	52.4	3%	0.033	28%	0.279	C	S	.	.	H	α-helix	trans	-57.7	-31.3	-175.3	0	0	0	0	0	112.4	S102 K108 P160 P164	S102-A106 PolarHBondContact O-N 3.23Å; A106-K108 VanDerWaalsContact C-N 3.3Å; A106-K108 PolarHBondContact O-N 3.25Å; A106-P160 HydrophobicContact CB-CB 4.26Å; A106-P160 HydrophobicContact CB-CG 4.29Å; A106-P164 HydrophobicContact CB-CB 4.27Å
107	C	56	Low	66.9	Low	104 Å²	104	55.4 Å²	55.4	70%	0.703	29%	0.291	S	S	*	.	H	α-helix	trans	-66.1	-26.1	174.5	-64.8	0	0	0	0	114	L105	L105-C107 PolarHBondContact O-N 2.65Å; L105-C107 VanDerWaalsContact O-N 3.14Å
108	K	56.7	Low	67.1	Low	148 Å²	148	50.7 Å²	50.7	64%	0.643	26%	0.262	S	S	*	.	H	α-helix	trans	-88.8	-38	-173.8	-73.3	-171.1	172.3	-176.1	0	114.3	W104 L105 A106	W104-K108 HydrophobicContact CH2-CD 4.46Å; W104-K108 VanDerWaalsContact CH2-NZ 3.31Å; L105-K108 PolarHBondContact O-N 2.84Å; A106-K108 VanDerWaalsContact C-N 3.3Å; A106-K108 PolarHBondContact O-N 3.25Å
109	V	60.1	Low	67.9	Low	53 Å²	53	50.3 Å²	50.3	32%	0.321	26%	0.26	S	S	.	.	H	α-helix	trans	-104.9	-20.6	-164.8	-177.6	0	0	0	0	114	L114 L159	V109-L114 HydrophobicContact CB-CD1 3.81Å; V109-L114 HydrophobicContact CG1-CD1 4.13Å; V109-L159 HydrophobicContact CB-CD2 4.15Å; V109-L159 HydrophobicContact CG1-CD2 3.62Å; V109-L159 HydrophobicContact CG2-CD2 3.76Å
110	G	62.8	Low	68.9	Low	19 Å²	19	50.1 Å²	50.1	20%	0.196	26%	0.262	C	S	.	.			trans	90.6	120.6	177.1	0	0	0	0	0	113.8	R112 L114	G110-R112 PolarHBondContact O-N 3.38Å; G110-L114 VanDerWaalsContact C-CD1 3.42Å; G110-L114 WeakPolarHBondContact O-CD1 3.38Å
111	G	69.2	Low	70.1	Confident	4 Å²	4	46.9 Å²	46.9	4%	0.041	25%	0.245	C	C	.	.	H	α-helix	trans	-56.9	-20.8	-166.5	0	0	0	0	0	116.8	L114 L115 L169	G111-L114 VanDerWaalsContact O-CB 3.25Å; G111-L114 WeakPolarHBondContact O-CB 3.32Å; G111-L115 WeakPolarHBondContact O-CB 3.47Å; G111-L115 PolarHBondContact O-N 3.05Å; G111-L115 VanDerWaalsContact O-N 3.11Å; G111-L169 VanDerWaalsContact C-CD1 3.47Å
112	R	80.8	Confident	71.6	Confident	39 Å²	39	43.8 Å²	43.8	15%	0.147	23%	0.225	C	C	.	.	H	α-helix	trans	-66.9	-61.1	-179.3	-176.6	-174.4	69.9	117.2	7.5	112.5	G110 L114 L115 G116 L169 W228 M229 V232 D234	G110-R112 PolarHBondContact O-N 3.38Å; R112-L114 PolarHBondContact O-N 3.25Å; R112-L115 PolarHBondContact O-N 2.83Å; R112-G116 PolarHBondContact O-N 3.44Å; R112-L169 HydrophobicContact CB-CD2 4.34Å; R112-W228 HydrophobicContact CG-CZ2 4.38Å; R112-W228 PolarHBondContact O-NE1 2.96Å; R112-M229 PolarHBondContact NH1-O 3.45Å; R112-V232 WeakPolarHBondContact CD-O 3.19Å; R112-V232 HydrophobicContact CG-CB 4.2Å; R112-V232 HydrophobicContact CG-CG1 3.97Å; R112-V232 PolarHBondContact NH1-O 3.22Å; R112-D234 WeakPolarHBondContact CB-OD1 3.48Å; R112-D234 IonicContact CZ-OD2 3.6Å; R112-D234 IonicContact NE-OD1 3.79Å; R112-D234 IonicContact NE-OD2 3.25Å; R112-D234 PolarHBondContact NE-OD2 2.96Å; R112-D234 VanDerWaalsContact NE-OD2 3.13Å; R112-D234 IonicContact NH2-OD2 3.13Å
113	R	79.2	Confident	73.3	Confident	126 Å²	126	43.2 Å²	43.2	48%	0.475	22%	0.221	S	C	.	.	H	α-helix	trans	-57.6	-37	-175	-64	-179.2	-179.6	-179.1	-4.9	110.6	F117 R153 M229	R113-F117 HydrophobicContact CB-CD2 4.38Å; R113-F117 HydrophobicContact CB-CE2 4.12Å; R113-F117 WeakPolarHBondContact O-CD2 3.35Å; R113-F117 PolarHBondContact O-N 2.75Å; R113-R153 PolarHBondContact O-NH2 2.94Å; R113-M229 HydrophobicContact CG-CE 4.27Å
114	L	74.3	Confident	75.3	Confident	1 Å²	1	43.4 Å²	43.4	1%	0.005	22%	0.218	C	C	.	.	H	α-helix	trans	-54.8	-61.8	176.4	-104	143	0	0	0	114.8	V109 G110 G111 R112 G118 R153 P160 S165	V109-L114 HydrophobicContact CB-CD1 3.81Å; V109-L114 HydrophobicContact CG1-CD1 4.13Å; G110-L114 VanDerWaalsContact C-CD1 3.42Å; G110-L114 WeakPolarHBondContact O-CD1 3.38Å; G111-L114 VanDerWaalsContact O-CB 3.25Å; G111-L114 WeakPolarHBondContact O-CB 3.32Å; R112-L114 PolarHBondContact O-N 3.25Å; L114-G118 PolarHBondContact O-N 3.02Å; L114-G118 VanDerWaalsContact O-N 3.14Å; L114-R153 VanDerWaalsContact C-NH2 3.31Å; L114-R153 PolarHBondContact O-NE 3.36Å; L114-R153 PolarHBondContact O-NH2 2.58Å; L114-P160 HydrophobicContact CD1-CG 3.69Å; L114-P160 HydrophobicContact CD2-CB 3.5Å; L114-P160 HydrophobicContact CD2-CG 3.16Å; L114-P160 WeakPolarHBondContact CD2-O 2.87Å; L114-P160 HydrophobicContact CG-CG 3.88Å; L114-S165 WeakPolarHBondContact CB-OG 3.11Å; L114-S165 WeakPolarHBondContact CD2-OG 2.93Å
115	L	81	Confident	77.2	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-63.9	-41.8	175.9	163.5	60.4	0	0	0	111	G111 R112 G118 I119 T162 M166 L169 W224 W228	G111-L115 WeakPolarHBondContact O-CB 3.47Å; G111-L115 PolarHBondContact O-N 3.05Å; G111-L115 VanDerWaalsContact O-N 3.11Å; R112-L115 PolarHBondContact O-N 2.83Å; L115-G118 PolarHBondContact O-N 3.4Å; L115-I119 HydrophobicContact CD1-CD1 3.48Å; L115-I119 VanDerWaalsContact CD1-CD1 3.48Å; L115-I119 HydrophobicContact CD1-CG1 4.25Å; L115-I119 PolarHBondContact O-N 3.06Å; L115-T162 HydrophobicContact CB-CG2 4.32Å; L115-T162 HydrophobicContact CD1-CG2 3.11Å; L115-T162 HydrophobicContact CG-CG2 4.25Å; L115-M166 HydrophobicContact CD2-SD 4.01Å; L115-L169 HydrophobicContact CD2-CD1 4.44Å; L115-W224 HydrophobicContact CD1-CH2 3.77Å; L115-W224 HydrophobicContact CD1-CZ3 4.25Å; L115-W224 HydrophobicContact CD2-CH2 4.11Å; L115-W224 HydrophobicContact CG-CH2 3.71Å; L115-W224 HydrophobicContact CG-CZ3 4.31Å; L115-W228 HydrophobicContact CB-CZ2 4.48Å; L115-W228 HydrophobicContact CD2-CD2 4.4Å; L115-W228 HydrophobicContact CD2-CE3 4.43Å; L115-W228 HydrophobicContact CD2-CH2 3.5Å; L115-W228 VanDerWaalsContact CD2-CH2 3.5Å; L115-W228 HydrophobicContact CD2-CZ2 3.45Å; L115-W228 VanDerWaalsContact CD2-CZ2 3.45Å; L115-W228 HydrophobicContact CD2-CZ3 3.98Å; L115-W228 HydrophobicContact CG-CZ2 4.13Å
116	G	86.5	Confident	79.3	Confident	0 Å²	0	35 Å²	35	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-56.3	-69.1	177.6	0	0	0	0	0	113.4	R112 G118 I119 G120 S225	R112-G116 PolarHBondContact O-N 3.44Å; G116-G118 PolarHBondContact O-N 3.3Å; G116-I119 PolarHBondContact O-N 3.21Å; G116-G120 PolarHBondContact O-N 3.39Å; G116-S225 WeakPolarHBondContact O-CB 3.49Å; G116-S225 PolarHBondContact O-OG 3.37Å
117	F	85.6	Confident	81.3	Confident	98 Å²	98	37.6 Å²	37.6	43%	0.43	20%	0.199	S	C	.	.	H	α-helix	trans	-66.8	-21	-178.1	-41	-73.6	0	0	0	113.4	R113 I121 M229	R113-F117 HydrophobicContact CB-CD2 4.38Å; R113-F117 HydrophobicContact CB-CE2 4.12Å; R113-F117 WeakPolarHBondContact O-CD2 3.35Å; R113-F117 PolarHBondContact O-N 2.75Å; F117-I121 HydrophobicContact CB-CD1 4.24Å; F117-I121 VanDerWaalsContact O-CB 3.31Å; F117-I121 WeakPolarHBondContact O-CB 3.43Å; F117-I121 WeakPolarHBondContact O-CD1 3.24Å; F117-I121 WeakPolarHBondContact O-CG1 3.26Å; F117-I121 PolarHBondContact O-N 2.86Å; F117-M229 HydrophobicContact CE1-CE 3.92Å; F117-M229 HydrophobicContact CE2-CE 3.96Å; F117-M229 HydrophobicContact CZ-CE 3.56Å
118	G	84.3	Confident	83.2	Confident	0 Å²	0	37.1 Å²	37.1	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-63	-51.4	175.5	0	0	0	0	0	111.3	L114 L115 G116 C122 S150	L114-G118 PolarHBondContact O-N 3.02Å; L114-G118 VanDerWaalsContact O-N 3.14Å; L115-G118 PolarHBondContact O-N 3.4Å; G116-G118 PolarHBondContact O-N 3.3Å; G118-C122 WeakPolarHBondContact O-CB 3.14Å; G118-C122 PolarHBondContact O-N 3.5Å; G118-S150 WeakPolarHBondContact CA-O 3.42Å
119	I	88.9	Confident	84.9	Confident	1 Å²	1	30.1 Å²	30.1	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-68.6	-39.6	175.8	-68	175.6	0	0	0	111.1	L41 M44 L115 G116 C122 G123 T162 W224	L41-I119 HydrophobicContact CB-CD1 4.41Å; L41-I119 HydrophobicContact CD1-CD1 4.29Å; L41-I119 HydrophobicContact CD1-CG1 4.16Å; M44-I119 HydrophobicContact CE-CG2 4.16Å; L115-I119 HydrophobicContact CD1-CD1 3.48Å; L115-I119 VanDerWaalsContact CD1-CD1 3.48Å; L115-I119 HydrophobicContact CD1-CG1 4.25Å; L115-I119 PolarHBondContact O-N 3.06Å; G116-I119 PolarHBondContact O-N 3.21Å; I119-C122 PolarHBondContact O-N 2.96Å; I119-G123 PolarHBondContact O-N 2.88Å; I119-T162 HydrophobicContact CD1-CG2 4.43Å; I119-T162 HydrophobicContact CG1-CG2 4.46Å; I119-W224 HydrophobicContact CB-CE3 4Å; I119-W224 HydrophobicContact CB-CZ3 3.94Å; I119-W224 HydrophobicContact CD1-CE3 3.87Å; I119-W224 HydrophobicContact CD1-CH2 3.79Å; I119-W224 HydrophobicContact CD1-CZ3 3.42Å; I119-W224 VanDerWaalsContact CD1-CZ3 3.42Å; I119-W224 HydrophobicContact CG1-CZ3 4.17Å; I119-W224 HydrophobicContact CG2-CE3 3.72Å; I119-W224 HydrophobicContact CG2-CZ3 4.17Å
120	G	91.4	Very high	86.4	Confident	11 Å²	11	29.7 Å²	29.7	11%	0.113	15%	0.153	C	C	.	.	H	α-helix	trans	-61.9	-45.4	178.5	0	0	0	0	0	113.6	G116 G123 A124	G116-G120 PolarHBondContact O-N 3.39Å; G120-G123 PolarHBondContact O-N 3.5Å; G120-A124 PolarHBondContact O-N 3.4Å
121	I	90.6	Very high	87.7	Confident	57 Å²	57	31.9 Å²	31.9	29%	0.292	17%	0.165	S	C	.	.	H	α-helix	trans	-67.8	-43.3	176.4	-65.2	164.6	0	0	0	110.1	F117 G123 A124 L125 I154	F117-I121 HydrophobicContact CB-CD1 4.24Å; F117-I121 VanDerWaalsContact O-CB 3.31Å; F117-I121 WeakPolarHBondContact O-CB 3.43Å; F117-I121 WeakPolarHBondContact O-CD1 3.24Å; F117-I121 WeakPolarHBondContact O-CG1 3.26Å; F117-I121 PolarHBondContact O-N 2.86Å; I121-G123 PolarHBondContact O-N 2.92Å; I121-A124 PolarHBondContact O-N 3.07Å; I121-L125 HydrophobicContact CG2-CD1 3.86Å; I121-L125 HydrophobicContact CG2-CG 4.18Å; I121-L125 WeakPolarHBondContact O-CB 3.16Å; I121-L125 VanDerWaalsContact O-CG 3.26Å; I121-L125 WeakPolarHBondContact O-CG 3.31Å; I121-L125 PolarHBondContact O-N 3.31Å; I121-I154 HydrophobicContact CD1-CD1 3.82Å; I121-I154 HydrophobicContact CG2-CD1 3.9Å
122	C	91.2	Very high	88.8	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-56.6	-41.4	174.8	-170.6	0	0	0	0	111.7	M44 G118 I119 L125 A126 S150 Q151	M44-C122 HydrophobicContact CE-CB 3.97Å; M44-C122 HydrophobicContact SD-CB 4.45Å; G118-C122 WeakPolarHBondContact O-CB 3.14Å; G118-C122 PolarHBondContact O-N 3.5Å; I119-C122 PolarHBondContact O-N 2.96Å; C122-L125 PolarHBondContact O-N 3.39Å; C122-A126 PolarHBondContact O-N 3.36Å; C122-S150 VanDerWaalsContact CA-OG 3.3Å; C122-S150 WeakPolarHBondContact CA-OG 3.44Å; C122-S150 VanDerWaalsContact CB-OG 3.24Å; C122-S150 WeakPolarHBondContact CB-OG 3.12Å; C122-S150 PolarHBondContact N-OG 2.84Å; C122-Q151 HydrophobicContact CB-CG 4.11Å; C122-Q151 PolarHBondContact SG-NE2 3.03Å; C122-Q151 VanDerWaalsContact SG-NE2 3.39Å
123	G	93.3	Very high	89.3	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-65.1	-44.6	176.3	0	0	0	0	0	112.8	I119 G120 I121 L125 A126 L127 G218	I119-G123 PolarHBondContact O-N 2.88Å; G120-G123 PolarHBondContact O-N 3.5Å; I121-G123 PolarHBondContact O-N 2.92Å; G123-L125 VanDerWaalsContact C-N 3.34Å; G123-L125 PolarHBondContact O-N 2.97Å; G123-A126 WeakPolarHBondContact O-CB 3.21Å; G123-A126 PolarHBondContact O-N 3.12Å; G123-A126 VanDerWaalsContact O-N 3.15Å; G123-L127 PolarHBondContact O-N 2.9Å; G123-G218 WeakPolarHBondContact O-CA 2.98Å
124	A	93.8	Very high	89.7	Confident	44 Å²	44	32.5 Å²	32.5	36%	0.364	17%	0.17	S	C	.	.	H	α-helix	trans	-61.4	-41.7	174.8	0	0	0	0	0	112.3	G120 I121 A126 L127 I222	G120-A124 PolarHBondContact O-N 3.4Å; I121-A124 PolarHBondContact O-N 3.07Å; A124-A126 VanDerWaalsContact C-N 3.3Å; A124-A126 PolarHBondContact O-N 3.25Å; A124-L127 WeakPolarHBondContact O-CB 3.01Å; A124-L127 PolarHBondContact O-N 3.41Å; A124-I222 HydrophobicContact CB-CD1 4.36Å
125	L	94	Very high	90.4	Very high	25 Å²	25	37 Å²	37	13%	0.131	20%	0.201	C	C	.	.	H	α-helix	trans	-66.6	-32.1	175.2	-66.1	170.7	0	0	0	112	I121 C122 G123 L127 L128 L143 V146 Q147	I121-L125 HydrophobicContact CG2-CD1 3.86Å; I121-L125 HydrophobicContact CG2-CG 4.18Å; I121-L125 WeakPolarHBondContact O-CB 3.16Å; I121-L125 VanDerWaalsContact O-CG 3.26Å; I121-L125 WeakPolarHBondContact O-CG 3.31Å; I121-L125 PolarHBondContact O-N 3.31Å; C122-L125 PolarHBondContact O-N 3.39Å; G123-L125 VanDerWaalsContact C-N 3.34Å; G123-L125 PolarHBondContact O-N 2.97Å; L125-L127 PolarHBondContact O-N 2.9Å; L125-L128 HydrophobicContact CD2-CD1 4.38Å; L125-L128 WeakPolarHBondContact O-CB 3.42Å; L125-L128 PolarHBondContact O-N 3.47Å; L125-L143 HydrophobicContact CB-CD1 3.98Å; L125-L143 HydrophobicContact CD2-CD1 3.76Å; L125-L143 HydrophobicContact CG-CD1 4.41Å; L125-V146 HydrophobicContact CD1-CB 4.29Å; L125-V146 HydrophobicContact CD1-CG1 3.67Å; L125-V146 HydrophobicContact CD2-CG1 4.34Å; L125-Q147 HydrophobicContact CB-CG 3.67Å; L125-Q147 HydrophobicContact CD1-CG 4.09Å
126	A	94	Very high	90.9	Very high	1 Å²	1	39 Å²	39	1%	0.008	22%	0.215	C	C	.	.	H	α-helix	trans	-62.9	-32.4	173.5	0	0	0	0	0	112.1	C122 G123 A124 L128 T129 Q147 F214	C122-A126 PolarHBondContact O-N 3.36Å; G123-A126 WeakPolarHBondContact O-CB 3.21Å; G123-A126 PolarHBondContact O-N 3.12Å; G123-A126 VanDerWaalsContact O-N 3.15Å; A124-A126 VanDerWaalsContact C-N 3.3Å; A124-A126 PolarHBondContact O-N 3.25Å; A126-L128 PolarHBondContact O-N 3.1Å; A126-T129 VanDerWaalsContact O-CB 3.26Å; A126-T129 WeakPolarHBondContact O-CB 3.36Å; A126-T129 PolarHBondContact O-N 3.46Å; A126-T129 VanDerWaalsContact O-N 3.13Å; A126-T129 PolarHBondContact O-OG1 3.4Å; A126-T129 VanDerWaalsContact O-OG1 3.09Å; A126-Q147 VanDerWaalsContact CA-NE2 3.29Å; A126-F214 WeakPolarHBondContact O-CB 3.46Å
127	L	94.7	Very high	91.1	Very high	59 Å²	59	40.1 Å²	40.1	31%	0.309	22%	0.223	S	C	.	.	H	α-helix	trans	-65	-24	173.1	-54.1	-175.2	0	0	0	112.8	G123 A124 L125 T129 Y215 I222	G123-L127 PolarHBondContact O-N 2.9Å; A124-L127 WeakPolarHBondContact O-CB 3.01Å; A124-L127 PolarHBondContact O-N 3.41Å; L125-L127 PolarHBondContact O-N 2.9Å; L127-T129 VanDerWaalsContact C-N 3.33Å; L127-Y215 HydrophobicContact CD2-CD1 4.09Å; L127-Y215 WeakPolarHBondContact O-CE1 3.41Å; L127-I222 HydrophobicContact CD1-CD1 3.69Å; L127-I222 HydrophobicContact CG-CD1 4.33Å
128	L	94.6	Very high	91.5	Very high	93 Å²	93	43.5 Å²	43.5	49%	0.487	23%	0.234	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	-4.1	177.6	-57.6	178.9	0	0	0	113.1	L125 A126 F130 S131 A132 L143	L125-L128 HydrophobicContact CD2-CD1 4.38Å; L125-L128 WeakPolarHBondContact O-CB 3.42Å; L125-L128 PolarHBondContact O-N 3.47Å; A126-L128 PolarHBondContact O-N 3.1Å; L128-F130 PolarHBondContact O-N 3.1Å; L128-S131 PolarHBondContact O-N 3.46Å; L128-A132 WeakPolarHBondContact O-CB 3.46Å; L128-A132 PolarHBondContact O-N 3.31Å; L128-L143 HydrophobicContact CB-CD1 4.11Å; L128-L143 HydrophobicContact CB-CD2 4.15Å; L128-L143 HydrophobicContact CD1-CD1 4.5Å
129	T	93	Very high	92	Very high	1 Å²	1	45.1 Å²	45.1	1%	0.006	25%	0.247	C	C	.	.	H	α-helix	trans	-61.1	-41.5	-174	-64.4	0	0	0	0	112.7	A126 L127 A132 A133 L140 L143 F214	A126-T129 VanDerWaalsContact O-CB 3.26Å; A126-T129 WeakPolarHBondContact O-CB 3.36Å; A126-T129 PolarHBondContact O-N 3.46Å; A126-T129 VanDerWaalsContact O-N 3.13Å; A126-T129 PolarHBondContact O-OG1 3.4Å; A126-T129 VanDerWaalsContact O-OG1 3.09Å; L127-T129 VanDerWaalsContact C-N 3.33Å; T129-A132 PolarHBondContact O-N 3.2Å; T129-A133 WeakPolarHBondContact O-CB 3.27Å; T129-A133 PolarHBondContact O-N 3.27Å; T129-L140 HydrophobicContact CG2-CD1 3.83Å; T129-L143 VanDerWaalsContact CA-CD2 3.49Å; T129-F214 HydrophobicContact CG2-CB 4.42Å; T129-F214 HydrophobicContact CG2-CD1 3.85Å; T129-F214 HydrophobicContact CG2-CD2 3.6Å; T129-F214 HydrophobicContact CG2-CE1 3.94Å; T129-F214 HydrophobicContact CG2-CE2 3.68Å; T129-F214 HydrophobicContact CG2-CG 3.69Å; T129-F214 HydrophobicContact CG2-CZ 3.85Å
130	F	91.3	Very high	92.3	Very high	45 Å²	45	45 Å²	45	20%	0.197	25%	0.247	C	C	.	.	H	α-helix	trans	-62.6	-50.5	177.2	177.8	-113.1	0	0	0	112.1	L128 A132 A133 R134 H209 W210 S211 Y215	L128-F130 PolarHBondContact O-N 3.1Å; F130-A132 VanDerWaalsContact C-N 3.31Å; F130-A132 PolarHBondContact O-N 2.88Å; F130-A133 PolarHBondContact O-N 2.95Å; F130-R134 HydrophobicContact CE2-CG 4.15Å; F130-R134 VanDerWaalsContact CZ-CD 3.43Å; F130-R134 HydrophobicContact CZ-CG 4.21Å; F130-R134 PolarHBondContact O-N 3.18Å; F130-R134 VanDerWaalsContact O-N 3.08Å; F130-H209 AromaticContact CE2-CE1 3.75Å; F130-W210 AromaticContact CD2-CH2 3.56Å; F130-W210 HydrophobicContact CD2-CH2 3.56Å; F130-W210 AromaticContact CD2-CZ2 3.68Å; F130-W210 HydrophobicContact CD2-CZ2 3.68Å; F130-W210 HydrophobicContact CD2-CZ3 4.28Å; F130-W210 HydrophobicContact CE2-CH2 4.28Å; F130-W210 AromaticContact CE2-CZ2 3.94Å; F130-W210 HydrophobicContact CE2-CZ2 3.94Å; F130-S211 VanDerWaalsContact CD2-CB 3.41Å; F130-Y215 HydrophobicContact CB-CE1 4.43Å; F130-Y215 WeakPolarHBondContact CB-OH 3.24Å; F130-Y215 VanDerWaalsContact CD1-OH 3.3Å; F130-Y215 WeakPolarHBondContact CD1-OH 3.4Å
131	S	91.1	Very high	92.4	Very high	65 Å²	65	46.3 Å²	46.3	46%	0.455	25%	0.251	S	S	.	.	H	α-helix	trans	-60.1	-42.9	179.5	-51.9	0	0	0	0	111.7	L128 R134 S135	L128-S131 PolarHBondContact O-N 3.46Å; S131-R134 PolarHBondContact O-N 2.72Å; S131-S135 PolarHBondContact O-N 3.14Å; S131-S135 VanDerWaalsContact O-N 3.14Å; S131-S135 PolarHBondContact O-OG 2.7Å; S131-S135 VanDerWaalsContact O-OG 3.08Å
132	A	92.3	Very high	92.6	Very high	13 Å²	13	46.2 Å²	46.2	11%	0.107	26%	0.258	C	S	.	.	H	α-helix	trans	-64.8	-43.2	178	0	0	0	0	0	112.3	L128 T129 F130 R134 S135 S136 A139 L140 L143	L128-A132 WeakPolarHBondContact O-CB 3.46Å; L128-A132 PolarHBondContact O-N 3.31Å; T129-A132 PolarHBondContact O-N 3.2Å; F130-A132 VanDerWaalsContact C-N 3.31Å; F130-A132 PolarHBondContact O-N 2.88Å; A132-R134 VanDerWaalsContact C-N 3.34Å; A132-R134 PolarHBondContact O-N 3.2Å; A132-S135 PolarHBondContact O-N 3.13Å; A132-S136 PolarHBondContact O-N 2.93Å; A132-A139 HydrophobicContact CB-CB 4.43Å; A132-L140 HydrophobicContact CB-CB 4.5Å; A132-L143 HydrophobicContact CB-CB 4.26Å; A132-L143 HydrophobicContact CB-CD2 3.72Å
133	A	90.6	Very high	92.8	Very high	4 Å²	4	47.1 Å²	47.1	3%	0.033	26%	0.263	C	S	.	.	H	α-helix	trans	-62.1	-39.7	178.3	0	0	0	0	0	112.5	M55 W79 T129 F130 L140 W210	M55-A133 HydrophobicContact CE-CB 3.91Å; W79-A133 HydrophobicContact CH2-CB 4.47Å; T129-A133 WeakPolarHBondContact O-CB 3.27Å; T129-A133 PolarHBondContact O-N 3.27Å; F130-A133 PolarHBondContact O-N 2.95Å; A133-L140 HydrophobicContact CB-CD2 4.18Å; A133-W210 HydrophobicContact CB-CH2 3.79Å
134	R	88.2	Confident	92.8	Very high	164 Å²	164	47.5 Å²	47.5	62%	0.619	26%	0.264	S	S	*	.	H	α-helix	trans	-70.6	-28.1	175.8	-75.4	-167.6	70.4	102.5	-3.8	113.9	E75 F130 S131 A132	E75-R134 IonicContact OE2-CZ 2.82Å; E75-R134 IonicContact OE2-NH1 3.62Å; E75-R134 PolarHBondContact OE2-NH1 2.58Å; F130-R134 HydrophobicContact CE2-CG 4.15Å; F130-R134 VanDerWaalsContact CZ-CD 3.43Å; F130-R134 HydrophobicContact CZ-CG 4.21Å; F130-R134 PolarHBondContact O-N 3.18Å; F130-R134 VanDerWaalsContact O-N 3.08Å; S131-R134 PolarHBondContact O-N 2.72Å; A132-R134 VanDerWaalsContact C-N 3.34Å; A132-R134 PolarHBondContact O-N 3.2Å
135	S	89	Confident	92.7	Very high	96 Å²	96	47.3 Å²	47.3	67%	0.671	26%	0.259	S	S	*	.	H	α-helix	trans	-73.2	-56.3	178.8	-63.6	0	0	0	0	111.8	S131 A132	S131-S135 PolarHBondContact O-N 3.14Å; S131-S135 VanDerWaalsContact O-N 3.14Å; S131-S135 PolarHBondContact O-OG 2.7Å; S131-S135 VanDerWaalsContact O-OG 3.08Å; A132-S135 PolarHBondContact O-N 3.13Å
136	S	90.4	Very high	92.5	Very high	42 Å²	42	48.9 Å²	48.9	29%	0.294	27%	0.269	S	S	.	.			trans	-169.4	156.3	174.3	63.7	0	0	0	0	110.9	A132 Y138 A139 L140	A132-S136 PolarHBondContact O-N 2.93Å; S136-Y138 PolarHBondContact O-N 2.87Å; S136-A139 PolarHBondContact O-N 3.29Å; S136-A139 VanDerWaalsContact O-N 3.14Å; S136-A139 WeakPolarHBondContact OG-CB 3.11Å; S136-A139 PolarHBondContact OG-N 3.27Å; S136-L140 PolarHBondContact O-N 2.56Å
137	P	91.5	Very high	92.3	Very high	24 Å²	24	49.1 Å²	49.1	16%	0.156	27%	0.27	C	S	.	.	H	α-helix	trans	-56.6	-34.4	170.7	20.5	-32	0	0	0	112.2	W79 T83 L140 I141	W79-P137 HydrophobicContact CD2-CB 4.06Å; W79-P137 HydrophobicContact CE3-CB 4.47Å; W79-P137 HydrophobicContact CH2-CB 4.32Å; W79-P137 HydrophobicContact CZ2-CB 3.88Å; T83-P137 HydrophobicContact CG2-CB 3.37Å; T83-P137 HydrophobicContact CG2-CG 3.93Å; P137-L140 PolarHBondContact O-N 3.26Å; P137-I141 WeakPolarHBondContact O-CG1 3.38Å; P137-I141 PolarHBondContact O-N 3.03Å
138	Y	93.9	Very high	92	Very high	168 Å²	168	46.3 Å²	46.3	66%	0.659	26%	0.255	S	S	*	.	H	α-helix	trans	-68.5	-36.3	178.5	-56.4	-69	0	0	0	113	S136 L140 I141 A142	S136-Y138 PolarHBondContact O-N 2.87Å; Y138-L140 VanDerWaalsContact C-N 3.32Å; Y138-I141 HydrophobicContact CD1-CD1 4.39Å; Y138-I141 PolarHBondContact O-N 3.36Å; Y138-A142 WeakPolarHBondContact O-CB 3.11Å; Y138-A142 PolarHBondContact O-N 3.48Å
139	A	94.6	Very high	91.4	Very high	34 Å²	34	43.5 Å²	43.5	28%	0.281	24%	0.24	S	C	.	.	H	α-helix	trans	-63.9	-40.4	172.8	0	0	0	0	0	111	A132 S136 A142 L143	A132-A139 HydrophobicContact CB-CB 4.43Å; S136-A139 PolarHBondContact O-N 3.29Å; S136-A139 VanDerWaalsContact O-N 3.14Å; S136-A139 WeakPolarHBondContact OG-CB 3.11Å; S136-A139 PolarHBondContact OG-N 3.27Å; A139-A142 PolarHBondContact O-N 3.18Å; A139-L143 WeakPolarHBondContact O-CB 3.2Å; A139-L143 PolarHBondContact O-N 3.27Å
140	L	94.3	Very high	90.6	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-65.4	-43.1	174.1	-179	59	0	0	0	112	M55 W79 V87 T129 A132 A133 S136 P137 Y138 A142 L143 R144	M55-L140 HydrophobicContact CE-CD2 4.22Å; W79-L140 HydrophobicContact CH2-CD2 3.7Å; W79-L140 HydrophobicContact CZ3-CD2 4.04Å; V87-L140 HydrophobicContact CG1-CD2 3.62Å; V87-L140 HydrophobicContact CG1-CG 4.14Å; V87-L140 HydrophobicContact CG2-CD2 4.35Å; T129-L140 HydrophobicContact CG2-CD1 3.83Å; A132-L140 HydrophobicContact CB-CB 4.5Å; A133-L140 HydrophobicContact CB-CD2 4.18Å; S136-L140 PolarHBondContact O-N 2.56Å; P137-L140 PolarHBondContact O-N 3.26Å; Y138-L140 VanDerWaalsContact C-N 3.32Å; L140-A142 VanDerWaalsContact C-N 3.34Å; L140-A142 PolarHBondContact O-N 3.24Å; L140-L143 HydrophobicContact CD1-CD2 4.4Å; L140-L143 PolarHBondContact O-N 3.03Å; L140-R144 HydrophobicContact CD1-CG 4.06Å; L140-R144 HydrophobicContact CG-CG 4.27Å; L140-R144 WeakPolarHBondContact O-CB 3.35Å; L140-R144 WeakPolarHBondContact O-CG 3.4Å; L140-R144 PolarHBondContact O-N 3.35Å
141	I	94.6	Very high	89.6	Confident	38 Å²	38	41.4 Å²	41.4	20%	0.195	23%	0.231	C	C	.	.	H	α-helix	trans	-56.6	-49.4	173.7	-72.6	166.4	0	0	0	110.2	A86 V87 P137 Y138 L143 R144 V145	A86-I141 HydrophobicContact CB-CD1 3.89Å; V87-I141 HydrophobicContact CB-CG1 4.47Å; V87-I141 HydrophobicContact CG2-CD1 4.16Å; V87-I141 HydrophobicContact CG2-CG1 3.7Å; P137-I141 WeakPolarHBondContact O-CG1 3.38Å; P137-I141 PolarHBondContact O-N 3.03Å; Y138-I141 HydrophobicContact CD1-CD1 4.39Å; Y138-I141 PolarHBondContact O-N 3.36Å; I141-L143 PolarHBondContact O-N 2.59Å; I141-R144 PolarHBondContact O-N 3.15Å; I141-V145 HydrophobicContact CG2-CG2 4.45Å; I141-V145 VanDerWaalsContact O-CG2 3.3Å; I141-V145 WeakPolarHBondContact O-CG2 3.5Å; I141-V145 PolarHBondContact O-N 2.91Å
142	A	94.5	Very high	88.1	Confident	54 Å²	54	38.3 Å²	38.3	45%	0.446	21%	0.21	S	C	.	.	H	α-helix	trans	-59.1	-46.3	177.9	0	0	0	0	0	111.4	Y138 A139 L140 R144 V145 V146	Y138-A142 WeakPolarHBondContact O-CB 3.11Å; Y138-A142 PolarHBondContact O-N 3.48Å; A139-A142 PolarHBondContact O-N 3.18Å; L140-A142 VanDerWaalsContact C-N 3.34Å; L140-A142 PolarHBondContact O-N 3.24Å; A142-R144 VanDerWaalsContact C-N 3.33Å; A142-R144 PolarHBondContact O-N 3.38Å; A142-V145 PolarHBondContact O-N 3.47Å; A142-V146 VanDerWaalsContact O-CG2 3.31Å; A142-V146 WeakPolarHBondContact O-CG2 3.3Å; A142-V146 PolarHBondContact O-N 3.48Å
143	L	94.5	Very high	86.3	Confident	20 Å²	20	38.3 Å²	38.3	11%	0.105	21%	0.207	C	C	.	.	H	α-helix	trans	-59.1	-43.5	176.6	-177.7	69.5	0	0	0	111.9	L125 L128 T129 A132 A139 L140 I141 V146 Q147	L125-L143 HydrophobicContact CB-CD1 3.98Å; L125-L143 HydrophobicContact CD2-CD1 3.76Å; L125-L143 HydrophobicContact CG-CD1 4.41Å; L128-L143 HydrophobicContact CB-CD1 4.11Å; L128-L143 HydrophobicContact CB-CD2 4.15Å; L128-L143 HydrophobicContact CD1-CD1 4.5Å; T129-L143 VanDerWaalsContact CA-CD2 3.49Å; A132-L143 HydrophobicContact CB-CB 4.26Å; A132-L143 HydrophobicContact CB-CD2 3.72Å; A139-L143 WeakPolarHBondContact O-CB 3.2Å; A139-L143 PolarHBondContact O-N 3.27Å; L140-L143 HydrophobicContact CD1-CD2 4.4Å; L140-L143 PolarHBondContact O-N 3.03Å; I141-L143 PolarHBondContact O-N 2.59Å; L143-V146 CarbonylContact O-C 3.48Å; L143-V146 PolarHBondContact O-N 2.91Å; L143-Q147 WeakPolarHBondContact O-CG 3.22Å; L143-Q147 PolarHBondContact O-N 3.4Å
144	R	93.2	Very high	83.9	Confident	8 Å²	8	39.5 Å²	39.5	3%	0.03	21%	0.213	C	C	.	.	H	α-helix	trans	-67.3	-38.8	179.2	-72.2	-71.5	-70.9	156.8	-13.2	112.3	L48 S90 L140 I141 A142 V146 Q147 G148	L48-R144 HydrophobicContact CD2-CG 4.42Å; S90-R144 WeakPolarHBondContact OG-CB 3.41Å; L140-R144 HydrophobicContact CD1-CG 4.06Å; L140-R144 HydrophobicContact CG-CG 4.27Å; L140-R144 WeakPolarHBondContact O-CB 3.35Å; L140-R144 WeakPolarHBondContact O-CG 3.4Å; L140-R144 PolarHBondContact O-N 3.35Å; I141-R144 PolarHBondContact O-N 3.15Å; A142-R144 VanDerWaalsContact C-N 3.33Å; A142-R144 PolarHBondContact O-N 3.38Å; R144-V146 VanDerWaalsContact C-N 3.32Å; R144-Q147 VanDerWaalsContact CD-OE1 3.26Å; R144-Q147 WeakPolarHBondContact O-CB 3.48Å; R144-Q147 PolarHBondContact O-N 2.91Å; R144-G148 PolarHBondContact O-N 2.98Å
145	V	91.8	Very high	81.6	Confident	40 Å²	40	36 Å²	36	24%	0.242	22%	0.218	C	C	.	.	H	α-helix	trans	-59.2	-46.4	170.4	173	0	0	0	0	109.6	S90 G94 I141 A142 Q147 G148 L149	S90-V145 WeakPolarHBondContact O-CG2 3.33Å; G94-V145 WeakPolarHBondContact CA-O 3.39Å; I141-V145 HydrophobicContact CG2-CG2 4.45Å; I141-V145 VanDerWaalsContact O-CG2 3.3Å; I141-V145 WeakPolarHBondContact O-CG2 3.5Å; I141-V145 PolarHBondContact O-N 2.91Å; A142-V145 PolarHBondContact O-N 3.47Å; V145-Q147 VanDerWaalsContact C-N 3.32Å; V145-Q147 PolarHBondContact O-N 2.85Å; V145-G148 PolarHBondContact O-N 3.32Å; V145-L149 HydrophobicContact CG1-CD1 4.13Å; V145-L149 HydrophobicContact CG1-CG 4.42Å; V145-L149 WeakPolarHBondContact O-CB 2.98Å; V145-L149 WeakPolarHBondContact O-CG 2.99Å; V145-L149 PolarHBondContact O-N 3Å
146	V	90.9	Very high	79.5	Confident	58 Å²	58	41.1 Å²	41.1	35%	0.352	23%	0.229	S	C	.	.	H	α-helix	trans	-66.3	-33.4	177.5	-176.1	0	0	0	0	111.7	L125 A142 L143 R144 L149 S150	L125-V146 HydrophobicContact CD1-CB 4.29Å; L125-V146 HydrophobicContact CD1-CG1 3.67Å; L125-V146 HydrophobicContact CD2-CG1 4.34Å; A142-V146 VanDerWaalsContact O-CG2 3.31Å; A142-V146 WeakPolarHBondContact O-CG2 3.3Å; A142-V146 PolarHBondContact O-N 3.48Å; L143-V146 CarbonylContact O-C 3.48Å; L143-V146 PolarHBondContact O-N 2.91Å; R144-V146 VanDerWaalsContact C-N 3.32Å; V146-L149 CarbonylContact O-C 3.11Å; V146-L149 WeakPolarHBondContact O-CB 3.28Å; V146-L149 PolarHBondContact O-N 3Å; V146-S150 WeakPolarHBondContact O-CB 3.38Å; V146-S150 PolarHBondContact O-N 3.38Å
147	Q	90.1	Very high	77.3	Confident	5 Å²	5	42.3 Å²	42.3	2%	0.023	23%	0.234	C	C	.	.	H	α-helix	trans	-63.9	-45.7	171.1	-77.4	-179.1	-20.2	0	0	112	F91 L125 A126 L143 R144 V145 L149 S150 Q151	F91-Q147 HydrophobicContact CD2-CB 4.24Å; F91-Q147 HydrophobicContact CE2-CB 4.39Å; L125-Q147 HydrophobicContact CB-CG 3.67Å; L125-Q147 HydrophobicContact CD1-CG 4.09Å; A126-Q147 VanDerWaalsContact CA-NE2 3.29Å; L143-Q147 WeakPolarHBondContact O-CG 3.22Å; L143-Q147 PolarHBondContact O-N 3.4Å; R144-Q147 VanDerWaalsContact CD-OE1 3.26Å; R144-Q147 WeakPolarHBondContact O-CB 3.48Å; R144-Q147 PolarHBondContact O-N 2.91Å; V145-Q147 VanDerWaalsContact C-N 3.32Å; V145-Q147 PolarHBondContact O-N 2.85Å; Q147-L149 VanDerWaalsContact C-N 3.33Å; Q147-L149 PolarHBondContact O-N 3.13Å; Q147-S150 WeakPolarHBondContact CA-OG 3.47Å; Q147-S150 WeakPolarHBondContact O-CA 3.27Å; Q147-S150 PolarHBondContact O-N 2.94Å; Q147-S150 PolarHBondContact O-OG 2.67Å; Q147-Q151 PolarHBondContact O-N 3Å
148	G	87.2	Confident	75.2	Confident	0 Å²	0	50 Å²	50	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-58.6	-47.1	173.6	0	0	0	0	0	111.7	F91 R144 V145 S150 Q151 A152	F91-G148 VanDerWaalsContact CE2-CA 3.42Å; F91-G148 WeakPolarHBondContact O-CA 3.29Å; R144-G148 PolarHBondContact O-N 2.98Å; V145-G148 PolarHBondContact O-N 3.32Å; G148-S150 PolarHBondContact O-N 3.42Å; G148-Q151 PolarHBondContact O-N 3.21Å; G148-A152 PolarHBondContact O-N 3.18Å; G148-A152 VanDerWaalsContact O-N 3.1Å
149	L	82.5	Confident	72.8	Confident	34 Å²	34	44.2 Å²	44.2	18%	0.178	25%	0.246	C	C	.	.	H	α-helix	trans	-61.5	-25.9	170.9	-71.7	172.4	0	0	0	111.9	G94 V97 T98 V145 V146 Q147 A152 R153 I154	G94-L149 WeakPolarHBondContact O-CD2 3.45Å; V97-L149 HydrophobicContact CB-CD2 4.11Å; V97-L149 HydrophobicContact CG1-CD2 4.19Å; T98-L149 HydrophobicContact CG2-CD2 3.83Å; V145-L149 HydrophobicContact CG1-CD1 4.13Å; V145-L149 HydrophobicContact CG1-CG 4.42Å; V145-L149 WeakPolarHBondContact O-CB 2.98Å; V145-L149 WeakPolarHBondContact O-CG 2.99Å; V145-L149 PolarHBondContact O-N 3Å; V146-L149 CarbonylContact O-C 3.11Å; V146-L149 WeakPolarHBondContact O-CB 3.28Å; V146-L149 PolarHBondContact O-N 3Å; Q147-L149 VanDerWaalsContact C-N 3.33Å; Q147-L149 PolarHBondContact O-N 3.13Å; L149-A152 CarbonylContact O-C 3.51Å; L149-R153 CarbonylContact O-C 3.55Å; L149-R153 WeakPolarHBondContact O-CA 3.24Å; L149-R153 PolarHBondContact O-N 2.76Å; L149-I154 PolarHBondContact O-N 3.3Å; L149-I154 VanDerWaalsContact O-N 3.16Å
150	S	77	Confident	70.6	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-82.9	-38.7	179.3	73.2	0	0	0	0	112.2	G118 C122 V146 Q147 G148 A152 R153	G118-S150 WeakPolarHBondContact CA-O 3.42Å; C122-S150 VanDerWaalsContact CA-OG 3.3Å; C122-S150 WeakPolarHBondContact CA-OG 3.44Å; C122-S150 VanDerWaalsContact CB-OG 3.24Å; C122-S150 WeakPolarHBondContact CB-OG 3.12Å; C122-S150 PolarHBondContact N-OG 2.84Å; V146-S150 WeakPolarHBondContact O-CB 3.38Å; V146-S150 PolarHBondContact O-N 3.38Å; Q147-S150 WeakPolarHBondContact CA-OG 3.47Å; Q147-S150 WeakPolarHBondContact O-CA 3.27Å; Q147-S150 PolarHBondContact O-N 2.94Å; Q147-S150 PolarHBondContact O-OG 2.67Å; G148-S150 PolarHBondContact O-N 3.42Å; S150-A152 PolarHBondContact O-N 2.9Å; S150-R153 PolarHBondContact O-N 2.95Å
151	Q	69.5	Low	68.6	Low	2 Å²	2	42.9 Å²	42.9	1%	0.009	23%	0.234	C	C	.	.	H	α-helix	trans	-66.3	-23.9	173.7	-69.8	-162.4	6.3	0	0	111.7	L41 F91 C122 Q147 G148 T162	L41-Q151 HydrophobicContact CG-CG 4.34Å; L41-Q151 PolarHBondContact O-NE2 3.47Å; L41-Q151 VanDerWaalsContact O-NE2 3.15Å; F91-Q151 HydrophobicContact CE2-CB 4.49Å; F91-Q151 HydrophobicContact CE2-CG 4.07Å; F91-Q151 HydrophobicContact CZ-CB 4.11Å; F91-Q151 VanDerWaalsContact CZ-CD 3.44Å; F91-Q151 HydrophobicContact CZ-CG 4.04Å; C122-Q151 HydrophobicContact CB-CG 4.11Å; C122-Q151 PolarHBondContact SG-NE2 3.03Å; C122-Q151 VanDerWaalsContact SG-NE2 3.39Å; Q147-Q151 PolarHBondContact O-N 3Å; G148-Q151 PolarHBondContact O-N 3.21Å; Q151-T162 WeakPolarHBondContact O-CB 3.33Å; Q151-T162 PolarHBondContact O-N 3.39Å; Q151-T162 PolarHBondContact O-OG1 2.89Å
152	A	58.8	Low	66.6	Low	1 Å²	1	41 Å²	41	1%	0.008	23%	0.225	C	C	.	.	H	α-helix	trans	-118	4.8	175	0	0	0	0	0	115.4	Y95 T98 G148 L149 S150 P160 P161	Y95-A152 HydrophobicContact CD2-CB 3.65Å; Y95-A152 HydrophobicContact CE2-CB 4.02Å; T98-A152 WeakPolarHBondContact CB-O 3.4Å; T98-A152 HydrophobicContact CG2-CB 4.17Å; T98-A152 WeakPolarHBondContact CG2-O 3.34Å; T98-A152 WeakPolarHBondContact OG1-CB 3.21Å; G148-A152 PolarHBondContact O-N 3.18Å; G148-A152 VanDerWaalsContact O-N 3.1Å; L149-A152 CarbonylContact O-C 3.51Å; S150-A152 PolarHBondContact O-N 2.9Å; A152-P160 CarbonylContact O-C 3.43Å; A152-P161 VanDerWaalsContact C-CA 3.43Å; A152-P161 VanDerWaalsContact CA-CB 3.49Å; A152-P161 HydrophobicContact CB-CB 3.79Å; A152-P161 HydrophobicContact CB-CG 4.37Å; A152-P161 WeakPolarHBondContact O-CA 3.3Å; A152-P161 WeakPolarHBondContact O-CB 3.42Å; A152-P161 WeakPolarHBondContact O-CD 2.71Å; A152-P161 WeakPolarHBondContact O-CG 3.49Å
153	R	54.5	Low	65.1	Low	12 Å²	12	40.5 Å²	40.5	5%	0.045	21%	0.212	C	C	.	.			trans	67.5	142.6	178.5	-75.6	-155.8	-172.4	-162.6	9.2	123.2	T98 R113 L114 L149 S150 L159 P160	T98-R153 WeakPolarHBondContact CG2-O 3.47Å; R113-R153 PolarHBondContact O-NH2 2.94Å; L114-R153 VanDerWaalsContact C-NH2 3.31Å; L114-R153 PolarHBondContact O-NE 3.36Å; L114-R153 PolarHBondContact O-NH2 2.58Å; L149-R153 CarbonylContact O-C 3.55Å; L149-R153 WeakPolarHBondContact O-CA 3.24Å; L149-R153 PolarHBondContact O-N 2.76Å; S150-R153 PolarHBondContact O-N 2.95Å; R153-L159 WeakPolarHBondContact CB-O 3.5Å; R153-P160 WeakPolarHBondContact CB-O 3.26Å; R153-P160 VanDerWaalsContact CD-O 3.24Å; R153-P160 WeakPolarHBondContact CD-O 3.16Å; R153-P160 WeakPolarHBondContact CG-O 3.22Å
154	I	40.3	Very low	63.5	Low	30 Å²	30	40.6 Å²	40.6	15%	0.154	21%	0.213	C	C	.	.			trans	-73.3	133.2	-160.9	-66	154.9	0	0	0	113.5	I121 L149 F156 T157	I121-I154 HydrophobicContact CD1-CD1 3.82Å; I121-I154 HydrophobicContact CG2-CD1 3.9Å; L149-I154 PolarHBondContact O-N 3.3Å; L149-I154 VanDerWaalsContact O-N 3.16Å; I154-F156 VanDerWaalsContact C-N 3.27Å; I154-F156 HydrophobicContact CG2-CB 3.81Å; I154-F156 PolarHBondContact O-N 3.12Å; I154-T157 CarbonylContact O-C 3.55Å; I154-T157 PolarHBondContact O-N 3.4Å
155	A	41.3	Very low	62.1	Low	89 Å²	89	40.2 Å²	40.2	74%	0.736	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	-57	-33.1	174.7	0	0	0	0	0	114.5	T157	A155-T157 VanDerWaalsContact C-N 3.3Å; A155-T157 PolarHBondContact O-N 3.45Å
156	F	43.1	Very low	61.2	Low	205 Å²	205	38.3 Å²	38.3	90%	0.899	20%	0.2	S	C	*	.	T	Hydrogen-bonded Turn	trans	-68.8	-21.7	-179	-83.2	-82.4	0	0	0	114.8	I154	I154-F156 VanDerWaalsContact C-N 3.27Å; I154-F156 HydrophobicContact CG2-CB 3.81Å; I154-F156 PolarHBondContact O-N 3.12Å
157	T	45.4	Very low	60	Low	66 Å²	66	40.7 Å²	40.7	41%	0.405	21%	0.207	S	C	.	.	T	Hydrogen-bonded Turn	trans	-123.6	105.6	168.8	53.8	0	0	0	0	105.5	I154 A155 L159	I154-T157 CarbonylContact O-C 3.55Å; I154-T157 PolarHBondContact O-N 3.4Å; A155-T157 VanDerWaalsContact C-N 3.3Å; A155-T157 PolarHBondContact O-N 3.45Å; T157-L159 WeakPolarHBondContact O-CA 3.06Å; T157-L159 VanDerWaalsContact O-CB 3.26Å; T157-L159 WeakPolarHBondContact O-CB 3.38Å; T157-L159 PolarHBondContact O-N 3.46Å
158	K	46.4	Very low	58.8	Low	186 Å²	186	41.5 Å²	41.5	81%	0.809	22%	0.215	S	C	*	.	T	Hydrogen-bonded Turn	trans	-51.7	73	-178.5	-68.2	179.9	177	176.5	0	112.6	L105	L105-K158 HydrophobicContact CD2-CB 4.41Å; L105-K158 WeakPolarHBondContact CD2-O 3.03Å
159	L	43.9	Very low	58.1	Low	47 Å²	47	41.6 Å²	41.6	25%	0.246	22%	0.216	C	C	.	.			trans	-141.8	139.3	-163.2	-67.1	177.9	0	0	0	109.7	V109 R153 T157	V109-L159 HydrophobicContact CB-CD2 4.15Å; V109-L159 HydrophobicContact CG1-CD2 3.62Å; V109-L159 HydrophobicContact CG2-CD2 3.76Å; R153-L159 WeakPolarHBondContact CB-O 3.5Å; T157-L159 WeakPolarHBondContact O-CA 3.06Å; T157-L159 VanDerWaalsContact O-CB 3.26Å; T157-L159 WeakPolarHBondContact O-CB 3.38Å; T157-L159 PolarHBondContact O-N 3.46Å
160	P	48.4	Very low	57.7	Low	2 Å²	2	40 Å²	40	1%	0.013	21%	0.208	C	C	.	.			trans	-86	174.6	-169	12	-11.5	0	0	0	120	L105 A106 L114 A152 R153	L105-P160 HydrophobicContact CB-CB 3.78Å; L105-P160 HydrophobicContact CB-CG 3.52Å; A106-P160 HydrophobicContact CB-CB 4.26Å; A106-P160 HydrophobicContact CB-CG 4.29Å; L114-P160 HydrophobicContact CD1-CG 3.69Å; L114-P160 HydrophobicContact CD2-CB 3.5Å; L114-P160 HydrophobicContact CD2-CG 3.16Å; L114-P160 WeakPolarHBondContact CD2-O 2.87Å; L114-P160 HydrophobicContact CG-CG 3.88Å; A152-P160 CarbonylContact O-C 3.43Å; R153-P160 WeakPolarHBondContact CB-O 3.26Å; R153-P160 VanDerWaalsContact CD-O 3.24Å; R153-P160 WeakPolarHBondContact CD-O 3.16Å; R153-P160 WeakPolarHBondContact CG-O 3.22Å
161	P	52.1	Low	57.2	Low	3 Å²	3	41.6 Å²	41.6	2%	0.019	22%	0.219	C	C	.	.			trans	-75.5	161.5	-178	-7.4	17.9	0	0	0	116.4	T98 S102 A152 P164 S165	T98-P161 WeakPolarHBondContact O-CG 3.35Å; S102-P161 VanDerWaalsContact CA-CG 3.43Å; S102-P161 VanDerWaalsContact CB-CG 3.45Å; A152-P161 VanDerWaalsContact C-CA 3.43Å; A152-P161 VanDerWaalsContact CA-CB 3.49Å; A152-P161 HydrophobicContact CB-CB 3.79Å; A152-P161 HydrophobicContact CB-CG 4.37Å; A152-P161 WeakPolarHBondContact O-CA 3.3Å; A152-P161 WeakPolarHBondContact O-CB 3.42Å; A152-P161 WeakPolarHBondContact O-CD 2.71Å; A152-P161 WeakPolarHBondContact O-CG 3.49Å; P161-P164 HydrophobicContact CB-CG 4.18Å; P161-P164 HydrophobicContact CG-CG 4.15Å; P161-S165 WeakPolarHBondContact O-CB 3.21Å; P161-S165 PolarHBondContact O-N 3.02Å; P161-S165 PolarHBondContact O-OG 2.9Å
162	T	53.7	Low	57.3	Low	0 Å²	0	44.6 Å²	44.6	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-70.7	-39.6	-174	-50.5	0	0	0	0	115	L41 L115 I119 Q151 S165 M166	L41-T162 HydrophobicContact CD1-CG2 3.63Å; L115-T162 HydrophobicContact CB-CG2 4.32Å; L115-T162 HydrophobicContact CD1-CG2 3.11Å; L115-T162 HydrophobicContact CG-CG2 4.25Å; I119-T162 HydrophobicContact CD1-CG2 4.43Å; I119-T162 HydrophobicContact CG1-CG2 4.46Å; Q151-T162 WeakPolarHBondContact O-CB 3.33Å; Q151-T162 PolarHBondContact O-N 3.39Å; Q151-T162 PolarHBondContact O-OG1 2.89Å; T162-S165 WeakPolarHBondContact O-CB 3.09Å; T162-S165 PolarHBondContact O-N 3.45Å; T162-M166 PolarHBondContact O-N 3Å
163	Y	62.6	Low	58.4	Low	43 Å²	43	44.7 Å²	44.7	17%	0.169	23%	0.232	C	C	.	.	H	α-helix	trans	-68.2	-51	-177.9	-84.7	-97.9	0	0	0	114.5	F38 L41 Y42 S165 M166 Y187	F38-Y163 AromaticContact CD1-CE1 3.99Å; F38-Y163 HydrophobicContact CD1-CE1 3.99Å; F38-Y163 HydrophobicContact CD1-CE2 4.34Å; F38-Y163 AromaticContact CD1-CZ 3.79Å; F38-Y163 AromaticContact CE1-CD1 3.67Å; F38-Y163 HydrophobicContact CE1-CD1 3.67Å; F38-Y163 HydrophobicContact CE1-CD2 4.09Å; F38-Y163 AromaticContact CE1-CE1 3.41Å; F38-Y163 HydrophobicContact CE1-CE1 3.41Å; F38-Y163 VanDerWaalsContact CE1-CE1 3.41Å; F38-Y163 AromaticContact CE1-CE2 3.83Å; F38-Y163 HydrophobicContact CE1-CE2 3.83Å; F38-Y163 AromaticContact CE1-CG 4Å; F38-Y163 HydrophobicContact CE1-CG 4Å; F38-Y163 AromaticContact CE1-CZ 3.46Å; F38-Y163 VanDerWaalsContact CE1-CZ 3.46Å; F38-Y163 HydrophobicContact CZ-CD1 4.31Å; F38-Y163 HydrophobicContact CZ-CE1 4.41Å; L41-Y163 HydrophobicContact CD2-CE2 4.18Å; Y42-Y163 HydrophobicContact CE2-CE2 4.45Å; Y42-Y163 WeakPolarHBondContact CE2-OH 3.42Å; Y42-Y163 PolarHBondContact OH-OH 2.92Å; Y163-S165 PolarHBondContact O-N 3.02Å; Y163-M166 PolarHBondContact O-N 2.84Å; Y163-Y187 HydrophobicContact CD1-CD1 4.01Å; Y163-Y187 AromaticContact CD1-CE1 3.58Å; Y163-Y187 HydrophobicContact CD1-CE1 3.58Å; Y163-Y187 AromaticContact CE1-CD1 3.87Å; Y163-Y187 HydrophobicContact CE1-CD1 3.87Å; Y163-Y187 AromaticContact CE1-CE1 3.94Å; Y163-Y187 HydrophobicContact CE1-CE1 3.94Å; Y163-Y187 PolarHBondContact O-OH 3.03Å
164	P	60.1	Low	59.4	Low	22 Å²	22	44.3 Å²	44.3	14%	0.143	23%	0.232	C	C	.	.	H	α-helix	trans	-63.2	-30.7	174.5	-13.7	24.1	0	0	0	112.2	S102 A106 P161 M166 Q167 A168	S102-P164 WeakPolarHBondContact OG-CG 3.45Å; A106-P164 HydrophobicContact CB-CB 4.27Å; P161-P164 HydrophobicContact CB-CG 4.18Å; P161-P164 HydrophobicContact CG-CG 4.15Å; P164-M166 PolarHBondContact O-N 3.31Å; P164-Q167 WeakPolarHBondContact O-CB 3.25Å; P164-Q167 PolarHBondContact O-N 3.07Å; P164-A168 PolarHBondContact O-N 2.59Å
165	S	65	Low	61.2	Low	0 Å²	0	43 Å²	43	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-59.3	-36.6	177.3	-65.3	0	0	0	0	112.3	L114 P161 T162 Y163 A168 L169	L114-S165 WeakPolarHBondContact CB-OG 3.11Å; L114-S165 WeakPolarHBondContact CD2-OG 2.93Å; P161-S165 WeakPolarHBondContact O-CB 3.21Å; P161-S165 PolarHBondContact O-N 3.02Å; P161-S165 PolarHBondContact O-OG 2.9Å; T162-S165 WeakPolarHBondContact O-CB 3.09Å; T162-S165 PolarHBondContact O-N 3.45Å; Y163-S165 PolarHBondContact O-N 3.02Å; S165-A168 PolarHBondContact O-N 3.25Å; S165-L169 PolarHBondContact O-N 3.21Å
166	M	73	Confident	62.4	Low	0 Å²	0	41 Å²	41	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-68.7	-38.1	175.1	-162.6	65.4	-156.4	0	0	112.1	A34 F38 L115 T162 Y163 P164 A168 L169 W170 V186	A34-M166 HydrophobicContact CB-CE 3.54Å; A34-M166 HydrophobicContact CB-SD 3.77Å; F38-M166 HydrophobicContact CE2-CB 4.19Å; F38-M166 HydrophobicContact CE2-CG 4.12Å; F38-M166 HydrophobicContact CZ-CB 4.17Å; L115-M166 HydrophobicContact CD2-SD 4.01Å; T162-M166 PolarHBondContact O-N 3Å; Y163-M166 PolarHBondContact O-N 2.84Å; P164-M166 PolarHBondContact O-N 3.31Å; M166-A168 VanDerWaalsContact C-N 3.33Å; M166-A168 PolarHBondContact O-N 3.35Å; M166-L169 PolarHBondContact O-N 3.36Å; M166-L169 HydrophobicContact SD-CD1 4.26Å; M166-W170 HydrophobicContact CE-CD2 3.97Å; M166-W170 HydrophobicContact CE-CG 4.42Å; M166-W170 HydrophobicContact CE-CH2 4.13Å; M166-W170 HydrophobicContact CE-CZ2 3.41Å; M166-W170 VanDerWaalsContact CE-CZ2 3.41Å; M166-W170 WeakPolarHBondContact O-CB 3.48Å; M166-W170 VanDerWaalsContact O-CD1 3.28Å; M166-W170 PolarHBondContact O-N 3.18Å; M166-V186 HydrophobicContact CE-CG1 4.38Å; M166-V186 HydrophobicContact CE-CG2 4.18Å; M166-V186 HydrophobicContact CG-CG1 3.99Å; M166-V186 HydrophobicContact SD-CG1 4.33Å
167	Q	65.6	Low	63.6	Low	107 Å²	107	40.1 Å²	40.1	50%	0.5	20%	0.197	S	C	.	.	H	α-helix	trans	-65.2	-39	174.4	-61.4	-170.8	-14.6	0	0	111.7	P164 W170 S171 Y187	P164-Q167 WeakPolarHBondContact O-CB 3.25Å; P164-Q167 PolarHBondContact O-N 3.07Å; Q167-W170 PolarHBondContact O-N 3.46Å; Q167-S171 PolarHBondContact O-N 3.27Å; Q167-Y187 VanDerWaalsContact CG-OH 3.28Å; Q167-Y187 WeakPolarHBondContact CG-OH 3.42Å
168	A	64.8	Low	65	Low	23 Å²	23	39.3 Å²	39.3	19%	0.19	19%	0.189	C	C	.	.	H	α-helix	trans	-62.9	-42.3	174	0	0	0	0	0	111.6	P164 S165 M166 S171	P164-A168 PolarHBondContact O-N 2.59Å; S165-A168 PolarHBondContact O-N 3.25Å; M166-A168 VanDerWaalsContact C-N 3.33Å; M166-A168 PolarHBondContact O-N 3.35Å; A168-S171 WeakPolarHBondContact O-CB 2.85Å; A168-S171 PolarHBondContact O-N 3.15Å; A168-S171 PolarHBondContact O-OG 3.46Å
169	L	72.8	Confident	66.1	Low	1 Å²	1	33 Å²	33	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-61.5	-45.9	172.1	-85.5	153.2	0	0	0	111.7	G111 R112 L115 S165 M166 S171 Q172 W173 W228	G111-L169 VanDerWaalsContact C-CD1 3.47Å; R112-L169 HydrophobicContact CB-CD2 4.34Å; L115-L169 HydrophobicContact CD2-CD1 4.44Å; S165-L169 PolarHBondContact O-N 3.21Å; M166-L169 PolarHBondContact O-N 3.36Å; M166-L169 HydrophobicContact SD-CD1 4.26Å; L169-S171 PolarHBondContact O-N 3.22Å; L169-Q172 PolarHBondContact O-N 3.25Å; L169-W173 WeakPolarHBondContact O-CB 3.32Å; L169-W173 PolarHBondContact O-N 3.45Å; L169-W228 HydrophobicContact CD1-CH2 4.05Å; L169-W228 HydrophobicContact CD1-CZ2 3.65Å
170	W	72.8	Confident	67.3	Low	2 Å²	2	34.6 Å²	34.6	1%	0.008	18%	0.18	C	C	.	.	H	α-helix	trans	-64.6	-26	178.3	-75.3	138.8	0	0	0	114.1	L30 T31 M166 Q167 Q172 W173 A174 R179 L182 V186	L30-W170 HydrophobicContact CD2-CH2 4.47Å; L30-W170 HydrophobicContact CD2-CZ3 4.17Å; T31-W170 VanDerWaalsContact OG1-CH2 3.26Å; T31-W170 WeakPolarHBondContact OG1-CH2 3.41Å; M166-W170 HydrophobicContact CE-CD2 3.97Å; M166-W170 HydrophobicContact CE-CG 4.42Å; M166-W170 HydrophobicContact CE-CH2 4.13Å; M166-W170 HydrophobicContact CE-CZ2 3.41Å; M166-W170 VanDerWaalsContact CE-CZ2 3.41Å; M166-W170 WeakPolarHBondContact O-CB 3.48Å; M166-W170 VanDerWaalsContact O-CD1 3.28Å; M166-W170 PolarHBondContact O-N 3.18Å; Q167-W170 PolarHBondContact O-N 3.46Å; W170-Q172 PolarHBondContact O-N 2.89Å; W170-W173 HydrophobicContact CE3-CB 4.1Å; W170-W173 HydrophobicContact CZ3-CB 4.27Å; W170-A174 HydrophobicContact CB-CB 4.12Å; W170-A174 HydrophobicContact CD2-CB 3.99Å; W170-A174 HydrophobicContact CE3-CB 3.37Å; W170-A174 HydrophobicContact CG-CB 4.34Å; W170-A174 HydrophobicContact CZ3-CB 4.09Å; W170-A174 WeakPolarHBondContact O-CB 3.38Å; W170-A174 PolarHBondContact O-N 3.49Å; W170-R179 HydrophobicContact CB-CG 4.32Å; W170-R179 PolarHBondContact O-NE 3.38Å; W170-R179 PolarHBondContact O-NH2 3.31Å; W170-L182 HydrophobicContact CE3-CD1 4.33Å; W170-L182 HydrophobicContact CH2-CB 3.75Å; W170-L182 HydrophobicContact CH2-CD1 4.02Å; W170-L182 HydrophobicContact CH2-CG 4.34Å; W170-L182 HydrophobicContact CZ2-CB 3.67Å; W170-L182 HydrophobicContact CZ3-CB 4.16Å; W170-L182 HydrophobicContact CZ3-CD1 3.76Å; W170-V186 HydrophobicContact CZ2-CG2 3.71Å
171	S	67.4	Low	68.6	Low	33 Å²	33	41 Å²	41	23%	0.231	21%	0.207	C	C	.	.	H	α-helix	trans	-60.5	-27.6	171.8	80.8	0	0	0	0	112.5	Q167 A168 L169 R179	Q167-S171 PolarHBondContact O-N 3.27Å; A168-S171 WeakPolarHBondContact O-CB 2.85Å; A168-S171 PolarHBondContact O-N 3.15Å; A168-S171 PolarHBondContact O-OG 3.46Å; L169-S171 PolarHBondContact O-N 3.22Å; S171-R179 PolarHBondContact O-NH2 3.4Å
172	Q	72.3	Confident	69.9	Low	65 Å²	65	40.8 Å²	40.8	30%	0.304	21%	0.206	S	C	.	.	H	α-helix	trans	-101.6	-37	-179.3	-56.1	-170.1	28.7	0	0	113.3	L169 W170 D234 P236 I250 R254	L169-Q172 PolarHBondContact O-N 3.25Å; W170-Q172 PolarHBondContact O-N 2.89Å; Q172-D234 PolarHBondContact OE1-O 3.23Å; Q172-P236 WeakPolarHBondContact O-CG 3.23Å; Q172-I250 VanDerWaalsContact O-CG2 3.27Å; Q172-I250 WeakPolarHBondContact O-CG2 3.48Å; Q172-R254 PolarHBondContact O-NH2 3Å
173	W	80.3	Confident	70.8	Confident	2 Å²	2	41.8 Å²	41.8	1%	0.008	21%	0.213	C	C	.	.	H	α-helix	trans	-98.5	-29.7	-170	-80.6	93.7	0	0	0	115.1	R26 L30 L169 W170 A233 D234 P236 D239 I242	R26-W173 HydrophobicContact CB-CZ3 4.43Å; R26-W173 HydrophobicContact CG-CH2 4.22Å; R26-W173 HydrophobicContact CG-CZ3 3.93Å; L30-W173 HydrophobicContact CD2-CB 3.7Å; L30-W173 HydrophobicContact CD2-CD2 3.57Å; L30-W173 HydrophobicContact CD2-CE3 3.94Å; L30-W173 HydrophobicContact CD2-CG 3.47Å; L30-W173 VanDerWaalsContact CD2-CG 3.47Å; L169-W173 WeakPolarHBondContact O-CB 3.32Å; L169-W173 PolarHBondContact O-N 3.45Å; W170-W173 HydrophobicContact CE3-CB 4.1Å; W170-W173 HydrophobicContact CZ3-CB 4.27Å; W173-A233 HydrophobicContact CZ2-CB 4.2Å; W173-A233 WeakPolarHBondContact CZ2-O 3.47Å; W173-A233 PolarHBondContact NE1-O 3.2Å; W173-A233 VanDerWaalsContact NE1-O 3.08Å; W173-D234 PolarHBondContact NE1-O 2.95Å; W173-P236 HydrophobicContact CD2-CB 4.25Å; W173-P236 HydrophobicContact CE3-CB 4.11Å; W173-P236 HydrophobicContact CH2-CB 4.26Å; W173-P236 HydrophobicContact CZ2-CB 4.41Å; W173-P236 HydrophobicContact CZ3-CB 4.12Å; W173-D239 HydrophobicContact CH2-CB 3.67Å; W173-D239 VanDerWaalsContact CH2-OD2 3.29Å; W173-D239 WeakPolarHBondContact CH2-OD2 3.44Å; W173-D239 HydrophobicContact CZ2-CB 4.19Å; W173-I242 HydrophobicContact CZ3-CD1 4.25Å
174	A	77.2	Confident	71.5	Confident	4 Å²	4	42.1 Å²	42.1	3%	0.033	23%	0.225	C	C	.	.	S	Bend	trans	-90.2	127.2	-178.5	0	0	0	0	0	110.8	W170 R179 L182	W170-A174 HydrophobicContact CB-CB 4.12Å; W170-A174 HydrophobicContact CD2-CB 3.99Å; W170-A174 HydrophobicContact CE3-CB 3.37Å; W170-A174 HydrophobicContact CG-CB 4.34Å; W170-A174 HydrophobicContact CZ3-CB 4.09Å; W170-A174 WeakPolarHBondContact O-CB 3.38Å; W170-A174 PolarHBondContact O-N 3.49Å; A174-R179 HydrophobicContact CB-CB 3.8Å; A174-R179 HydrophobicContact CB-CG 3.94Å; A174-R179 PolarHBondContact O-NH2 2.67Å; A174-L182 HydrophobicContact CB-CD1 3.92Å
175	P	76.6	Confident	72.7	Confident	4 Å²	4	44.2 Å²	44.2	3%	0.026	23%	0.234	C	C	.	.			trans	-56.6	140.7	161.2	-18.9	31.6	0	0	0	110	K177 E178 R179 L249 I250	P175-K177 VanDerWaalsContact C-N 3.31Å; P175-K177 PolarHBondContact O-N 3.35Å; P175-E178 PolarHBondContact O-N 2.64Å; P175-R179 PolarHBondContact O-N 3.3Å; P175-L249 HydrophobicContact CB-CD2 3.93Å; P175-L249 HydrophobicContact CG-CD2 3.44Å; P175-L249 VanDerWaalsContact CG-CD2 3.44Å; P175-I250 HydrophobicContact CG-CG1 4.25Å
176	E	66.7	Low	73.6	Confident	45 Å²	45	44.2 Å²	44.2	21%	0.21	23%	0.234	C	C	.	.	H	α-helix	trans	-52.5	-47.6	-173.9	-171.1	177.4	144.2	0	0	112.7	E178 R179	E176-E178 VanDerWaalsContact C-N 3.25Å; E176-E178 PolarHBondContact O-N 3.1Å; E176-R179 PolarHBondContact O-N 2.76Å
177	K	69.3	Low	74	Confident	188 Å²	188	46.7 Å²	46.7	82%	0.817	24%	0.244	S	C	*	.	H	α-helix	trans	-64.1	-25.4	-179.7	-62.6	-179.3	-178.2	174.5	0	114.1	P175	P175-K177 VanDerWaalsContact C-N 3.31Å; P175-K177 PolarHBondContact O-N 3.35Å
178	E	73.7	Confident	74.8	Confident	49 Å²	49	43.2 Å²	43.2	23%	0.229	23%	0.231	C	C	.	.	H	α-helix	trans	-102	-13	-178.7	-67.3	-173.8	-164.3	0	0	112.9	R27 Y28 P175 E176 A180 K181 L182	R27-E178 IonicContact CZ-OE1 3.51Å; R27-E178 IonicContact CZ-OE2 2.88Å; R27-E178 IonicContact NE-OE1 3.9Å; R27-E178 IonicContact NE-OE2 3.8Å; R27-E178 PolarHBondContact NE-OE2 2.95Å; R27-E178 IonicContact NH2-OE1 2.94Å; R27-E178 PolarHBondContact NH2-OE1 3.29Å; R27-E178 IonicContact NH2-OE2 3.86Å; R27-E178 PolarHBondContact NH2-OE2 3.34Å; R27-E178 VanDerWaalsContact NH2-OE2 3.15Å; Y28-E178 PolarHBondContact OH-OE2 3.3Å; P175-E178 PolarHBondContact O-N 2.64Å; E176-E178 VanDerWaalsContact C-N 3.25Å; E176-E178 PolarHBondContact O-N 3.1Å; E178-A180 VanDerWaalsContact C-N 3.33Å; E178-A180 PolarHBondContact O-N 3.41Å; E178-K181 WeakPolarHBondContact O-CB 3.33Å; E178-K181 PolarHBondContact O-N 2.94Å; E178-L182 HydrophobicContact CB-CD1 4.1Å; E178-L182 HydrophobicContact CB-CG 4.27Å; E178-L182 WeakPolarHBondContact O-CG 3.21Å; E178-L182 PolarHBondContact O-N 3.16Å
179	R	71	Confident	75.9	Confident	52 Å²	52	42.1 Å²	42.1	20%	0.196	22%	0.222	C	C	.	.	H	α-helix	trans	-54.9	-44.3	-172	-176.9	177.6	-70.7	155.2	2.8	113.5	W170 S171 A174 P175 E176 S183	W170-R179 HydrophobicContact CB-CG 4.32Å; W170-R179 PolarHBondContact O-NE 3.38Å; W170-R179 PolarHBondContact O-NH2 3.31Å; S171-R179 PolarHBondContact O-NH2 3.4Å; A174-R179 HydrophobicContact CB-CB 3.8Å; A174-R179 HydrophobicContact CB-CG 3.94Å; A174-R179 PolarHBondContact O-NH2 2.67Å; P175-R179 PolarHBondContact O-N 3.3Å; E176-R179 PolarHBondContact O-N 2.76Å; R179-S183 VanDerWaalsContact O-CB 3.3Å; R179-S183 WeakPolarHBondContact O-CB 3.32Å; R179-S183 PolarHBondContact O-N 3.16Å; R179-S183 PolarHBondContact O-OG 3.09Å
180	A	67.3	Low	76.5	Confident	81 Å²	81	42.4 Å²	42.4	67%	0.669	22%	0.224	S	C	*	.	H	α-helix	trans	-62.8	-45.3	178	0	0	0	0	0	111.3	E178 S183 A184	E178-A180 VanDerWaalsContact C-N 3.33Å; E178-A180 PolarHBondContact O-N 3.41Å; A180-S183 PolarHBondContact O-N 3.23Å; A180-A184 WeakPolarHBondContact O-CB 3.24Å; A180-A184 PolarHBondContact O-N 3.15Å
181	K	75.8	Confident	77.1	Confident	136 Å²	136	43.6 Å²	43.6	59%	0.591	23%	0.229	S	C	*	.	H	α-helix	trans	-61.6	-48.9	177.9	-178.4	-179.7	177.9	-179.7	0	111.6	E178 S183 A184 I185	E178-K181 WeakPolarHBondContact O-CB 3.33Å; E178-K181 PolarHBondContact O-N 2.94Å; K181-S183 VanDerWaalsContact C-N 3.34Å; K181-S183 PolarHBondContact O-N 2.8Å; K181-A184 PolarHBondContact O-N 2.88Å; K181-I185 HydrophobicContact CG-CD1 4.26Å; K181-I185 WeakPolarHBondContact O-CG1 3.39Å; K181-I185 PolarHBondContact O-N 3.44Å
182	L	80	Confident	78	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-65.4	-38.2	-179.9	-60.5	173.4	0	0	0	111.8	Y28 T31 W170 A174 E178 I185 V186	Y28-L182 HydrophobicContact CD1-CD2 4.02Å; Y28-L182 HydrophobicContact CE1-CD2 3.88Å; T31-L182 HydrophobicContact CG2-CD2 4.44Å; T31-L182 WeakPolarHBondContact OG1-CD2 3.43Å; W170-L182 HydrophobicContact CE3-CD1 4.33Å; W170-L182 HydrophobicContact CH2-CB 3.75Å; W170-L182 HydrophobicContact CH2-CD1 4.02Å; W170-L182 HydrophobicContact CH2-CG 4.34Å; W170-L182 HydrophobicContact CZ2-CB 3.67Å; W170-L182 HydrophobicContact CZ3-CB 4.16Å; W170-L182 HydrophobicContact CZ3-CD1 3.76Å; A174-L182 HydrophobicContact CB-CD1 3.92Å; E178-L182 HydrophobicContact CB-CD1 4.1Å; E178-L182 HydrophobicContact CB-CG 4.27Å; E178-L182 WeakPolarHBondContact O-CG 3.21Å; E178-L182 PolarHBondContact O-N 3.16Å; L182-I185 PolarHBondContact O-N 3.19Å; L182-V186 WeakPolarHBondContact O-CG2 3.19Å; L182-V186 PolarHBondContact O-N 3.23Å
183	S	73.8	Confident	78.9	Confident	20 Å²	20	43.9 Å²	43.9	14%	0.14	23%	0.226	C	C	.	.	H	α-helix	trans	-66.5	-43.2	175.8	-56.9	0	0	0	0	111.7	R179 A180 K181 I185 V186 Y187	R179-S183 VanDerWaalsContact O-CB 3.3Å; R179-S183 WeakPolarHBondContact O-CB 3.32Å; R179-S183 PolarHBondContact O-N 3.16Å; R179-S183 PolarHBondContact O-OG 3.09Å; A180-S183 PolarHBondContact O-N 3.23Å; K181-S183 VanDerWaalsContact C-N 3.34Å; K181-S183 PolarHBondContact O-N 2.8Å; S183-I185 VanDerWaalsContact C-N 3.34Å; S183-I185 PolarHBondContact O-N 3.24Å; S183-V186 PolarHBondContact O-N 3.11Å; S183-Y187 WeakPolarHBondContact O-CD2 3.38Å; S183-Y187 PolarHBondContact O-N 3.32Å
184	A	76.9	Confident	79.4	Confident	51 Å²	51	44 Å²	44	42%	0.421	23%	0.227	S	C	.	.	H	α-helix	trans	-59.5	-45	176	0	0	0	0	0	111.5	A180 K181 S188	A180-A184 WeakPolarHBondContact O-CB 3.24Å; A180-A184 PolarHBondContact O-N 3.15Å; K181-A184 PolarHBondContact O-N 2.88Å; A184-S188 WeakPolarHBondContact O-CB 3.23Å; A184-S188 PolarHBondContact O-N 3.49Å
185	I	83.8	Confident	80	Confident	66 Å²	66	45 Å²	45	34%	0.338	23%	0.233	S	C	.	.	H	α-helix	trans	-58.8	-53	174.9	-65	165.2	0	0	0	109.7	T31 F35 K181 L182 S183 Y187 S188	T31-I185 HydrophobicContact CG2-CB 3.85Å; T31-I185 HydrophobicContact CG2-CD1 4.41Å; T31-I185 HydrophobicContact CG2-CG2 3.49Å; T31-I185 VanDerWaalsContact CG2-CG2 3.49Å; F35-I185 VanDerWaalsContact CD2-O 3.27Å; F35-I185 WeakPolarHBondContact CD2-O 3.27Å; K181-I185 HydrophobicContact CG-CD1 4.26Å; K181-I185 WeakPolarHBondContact O-CG1 3.39Å; K181-I185 PolarHBondContact O-N 3.44Å; L182-I185 PolarHBondContact O-N 3.19Å; S183-I185 VanDerWaalsContact C-N 3.34Å; S183-I185 PolarHBondContact O-N 3.24Å; I185-Y187 PolarHBondContact O-N 3.13Å; I185-S188 WeakPolarHBondContact O-CB 3.27Å; I185-S188 PolarHBondContact O-N 3.44Å; I185-S188 VanDerWaalsContact O-N 3.15Å; I185-S188 PolarHBondContact O-OG 2.92Å
186	V	85.1	Confident	80.8	Confident	0 Å²	0	48.5 Å²	48.5	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-60.3	-45.4	-177.2	170.6	0	0	0	0	112.8	T31 A34 F38 M166 W170 L182 S183 S188 G189	T31-V186 HydrophobicContact CG2-CG2 3.88Å; A34-V186 HydrophobicContact CB-CB 4.46Å; A34-V186 HydrophobicContact CB-CG1 3.78Å; A34-V186 HydrophobicContact CB-CG2 3.75Å; F38-V186 HydrophobicContact CD2-CG1 3.27Å; F38-V186 HydrophobicContact CE2-CG1 3.32Å; F38-V186 HydrophobicContact CG-CG1 4.29Å; F38-V186 HydrophobicContact CZ-CG1 4.38Å; M166-V186 HydrophobicContact CE-CG1 4.38Å; M166-V186 HydrophobicContact CE-CG2 4.18Å; M166-V186 HydrophobicContact CG-CG1 3.99Å; M166-V186 HydrophobicContact SD-CG1 4.33Å; W170-V186 HydrophobicContact CZ2-CG2 3.71Å; L182-V186 WeakPolarHBondContact O-CG2 3.19Å; L182-V186 PolarHBondContact O-N 3.23Å; S183-V186 PolarHBondContact O-N 3.11Å; V186-S188 VanDerWaalsContact C-N 3.3Å; V186-S188 PolarHBondContact O-N 3.4Å; V186-G189 PolarHBondContact O-N 2.89Å; V186-G189 VanDerWaalsContact O-N 3.15Å
187	Y	81.2	Confident	82.1	Confident	52 Å²	52	46.7 Å²	46.7	20%	0.204	24%	0.243	C	C	.	.	H	α-helix	trans	-70.1	-26.4	178.8	-65.1	-49.1	0	0	0	112.7	F38 Y163 Q167 S183 I185 G189 S190	F38-Y187 HydrophobicContact CD1-CD1 4.31Å; F38-Y187 AromaticContact CE1-CD1 3.86Å; F38-Y187 HydrophobicContact CE1-CD1 3.86Å; F38-Y187 AromaticContact CE1-CE1 3.9Å; F38-Y187 HydrophobicContact CE1-CE1 3.9Å; F38-Y187 HydrophobicContact CE2-CE1 4.42Å; F38-Y187 AromaticContact CZ-CD1 3.96Å; F38-Y187 HydrophobicContact CZ-CD1 3.96Å; F38-Y187 AromaticContact CZ-CE1 3.69Å; F38-Y187 HydrophobicContact CZ-CE1 3.69Å; Y163-Y187 HydrophobicContact CD1-CD1 4.01Å; Y163-Y187 AromaticContact CD1-CE1 3.58Å; Y163-Y187 HydrophobicContact CD1-CE1 3.58Å; Y163-Y187 AromaticContact CE1-CD1 3.87Å; Y163-Y187 HydrophobicContact CE1-CD1 3.87Å; Y163-Y187 AromaticContact CE1-CE1 3.94Å; Y163-Y187 HydrophobicContact CE1-CE1 3.94Å; Y163-Y187 PolarHBondContact O-OH 3.03Å; Q167-Y187 VanDerWaalsContact CG-OH 3.28Å; Q167-Y187 WeakPolarHBondContact CG-OH 3.42Å; S183-Y187 WeakPolarHBondContact O-CD2 3.38Å; S183-Y187 PolarHBondContact O-N 3.32Å; I185-Y187 PolarHBondContact O-N 3.13Å; Y187-G189 PolarHBondContact O-N 3.38Å; Y187-G189 VanDerWaalsContact O-N 3.09Å; Y187-S190 PolarHBondContact O-N 2.81Å; Y187-S190 PolarHBondContact O-OG 3.03Å
188	S	82.8	Confident	83.2	Confident	33 Å²	33	37.8 Å²	37.8	23%	0.231	21%	0.205	C	C	.	.	H	α-helix	trans	-59.9	-21.6	172.3	75.1	0	0	0	0	113	F35 A184 I185 V186 S190 Y191 F192	F35-S188 WeakPolarHBondContact CE2-OG 3.44Å; A184-S188 WeakPolarHBondContact O-CB 3.23Å; A184-S188 PolarHBondContact O-N 3.49Å; I185-S188 WeakPolarHBondContact O-CB 3.27Å; I185-S188 PolarHBondContact O-N 3.44Å; I185-S188 VanDerWaalsContact O-N 3.15Å; I185-S188 PolarHBondContact O-OG 2.92Å; V186-S188 VanDerWaalsContact C-N 3.3Å; V186-S188 PolarHBondContact O-N 3.4Å; S188-S190 PolarHBondContact O-N 2.81Å; S188-Y191 PolarHBondContact O-N 3.48Å; S188-F192 PolarHBondContact O-N 3.37Å; S188-F192 VanDerWaalsContact O-N 3.13Å
189	G	86.7	Confident	84.1	Confident	0 Å²	0	36.4 Å²	36.4	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-58.1	-29.9	172.9	0	0	0	0	0	113.4	F35 C39 V186 Y187 Y191 F192 G193	F35-G189 VanDerWaalsContact CE2-N 3.32Å; C39-G189 WeakPolarHBondContact CA-O 3.49Å; C39-G189 PolarHBondContact N-O 3.47Å; C39-G189 VanDerWaalsContact SG-CA 3.54Å; C39-G189 PolarHBondContact SG-O 3.08Å; V186-G189 PolarHBondContact O-N 2.89Å; V186-G189 VanDerWaalsContact O-N 3.15Å; Y187-G189 PolarHBondContact O-N 3.38Å; Y187-G189 VanDerWaalsContact O-N 3.09Å; G189-Y191 PolarHBondContact O-N 3.08Å; G189-F192 PolarHBondContact O-N 3.25Å; G189-G193 PolarHBondContact O-N 3.45Å
190	S	86.3	Confident	85.1	Confident	7 Å²	7	36.9 Å²	36.9	5%	0.049	21%	0.209	C	C	.	.	H	α-helix	trans	-64.8	-42.1	177.1	59.9	0	0	0	0	112.4	Y42 Y187 S188 T194	Y42-S190 WeakPolarHBondContact CB-O 3.46Å; Y42-S190 WeakPolarHBondContact CD1-O 2.87Å; Y42-S190 VanDerWaalsContact CD2-CB 3.46Å; Y187-S190 PolarHBondContact O-N 2.81Å; Y187-S190 PolarHBondContact O-OG 3.03Å; S188-S190 PolarHBondContact O-N 2.81Å; S190-T194 PolarHBondContact O-N 3.28Å; S190-T194 VanDerWaalsContact O-N 3.12Å; S190-T194 PolarHBondContact O-OG1 3.05Å
191	Y	85.1	Confident	86.4	Confident	28 Å²	28	33.1 Å²	33.1	11%	0.11	18%	0.177	C	C	.	.	H	α-helix	trans	-69.1	-44.8	177.2	-61.4	-78.5	0	0	0	111.1	S188 G189 G193 T194 V195 M324 L328	S188-Y191 PolarHBondContact O-N 3.48Å; G189-Y191 PolarHBondContact O-N 3.08Å; Y191-G193 VanDerWaalsContact C-N 3.3Å; Y191-G193 PolarHBondContact O-N 2.72Å; Y191-T194 PolarHBondContact O-N 3.15Å; Y191-V195 WeakPolarHBondContact O-CG2 3.11Å; Y191-V195 PolarHBondContact O-N 3.34Å; Y191-M324 HydrophobicContact CD1-SD 4.45Å; Y191-M324 HydrophobicContact CE1-CE 3.99Å; Y191-M324 HydrophobicContact CE1-CG 4.48Å; Y191-M324 HydrophobicContact CE1-SD 3.92Å; Y191-L328 HydrophobicContact CD2-CD2 4.05Å; Y191-L328 HydrophobicContact CE2-CD2 3.33Å
192	F	87.4	Confident	87.1	Confident	100 Å²	100	26.7 Å²	26.7	44%	0.439	15%	0.149	S	C	.	.	H	α-helix	trans	-60.6	-41.9	177.4	-167.3	-101.2	0	0	0	111.7	F35 S188 G189 V195 I196	F35-F192 AromaticContact CE1-CD1 3.97Å; F35-F192 HydrophobicContact CE1-CD1 3.97Å; F35-F192 HydrophobicContact CE1-CE1 4.36Å; F35-F192 HydrophobicContact CE1-CG 4.45Å; F35-F192 HydrophobicContact CE2-CB 4.31Å; F35-F192 HydrophobicContact CZ-CB 3.82Å; F35-F192 AromaticContact CZ-CD1 3.75Å; F35-F192 HydrophobicContact CZ-CD1 3.75Å; F35-F192 HydrophobicContact CZ-CD2 4.47Å; F35-F192 HydrophobicContact CZ-CE1 4.39Å; F35-F192 AromaticContact CZ-CG 3.77Å; F35-F192 HydrophobicContact CZ-CG 3.77Å; S188-F192 PolarHBondContact O-N 3.37Å; S188-F192 VanDerWaalsContact O-N 3.13Å; G189-F192 PolarHBondContact O-N 3.25Å; F192-V195 PolarHBondContact O-N 3.48Å; F192-I196 HydrophobicContact CD1-CD1 3.68Å; F192-I196 HydrophobicContact CD1-CG1 4.48Å; F192-I196 HydrophobicContact CE1-CD1 3.12Å; F192-I196 HydrophobicContact CE1-CG1 4.25Å; F192-I196 HydrophobicContact CE2-CD1 4.25Å; F192-I196 HydrophobicContact CG-CD1 4.46Å; F192-I196 HydrophobicContact CZ-CD1 3.46Å; F192-I196 VanDerWaalsContact CZ-CD1 3.46Å; F192-I196 HydrophobicContact CZ-CG1 4.43Å; F192-I196 PolarHBondContact O-N 3.11Å
193	G	90.9	Very high	87.7	Confident	4 Å²	4	29.4 Å²	29.4	4%	0.041	16%	0.163	C	C	.	.	H	α-helix	trans	-55	-50.7	172.3	0	0	0	0	0	112.2	C39 G189 Y191 V195 I196 A197	C39-G193 WeakPolarHBondContact O-CA 3.48Å; G189-G193 PolarHBondContact O-N 3.45Å; Y191-G193 VanDerWaalsContact C-N 3.3Å; Y191-G193 PolarHBondContact O-N 2.72Å; G193-V195 PolarHBondContact O-N 2.96Å; G193-I196 PolarHBondContact O-N 3.4Å; G193-A197 WeakPolarHBondContact O-CB 3.37Å; G193-A197 PolarHBondContact O-N 3.27Å
194	T	89.2	Confident	88.5	Confident	3 Å²	3	30.1 Å²	30.1	2%	0.018	17%	0.165	C	C	.	.	H	α-helix	trans	-59.1	-47.7	176.9	-65.3	0	0	0	0	112.7	Y42 V46 S190 Y191 I196 A197 I198 L295 Y321	Y42-T194 WeakPolarHBondContact CD1-OG1 3.28Å; V46-T194 HydrophobicContact CG1-CG2 4.17Å; S190-T194 PolarHBondContact O-N 3.28Å; S190-T194 VanDerWaalsContact O-N 3.12Å; S190-T194 PolarHBondContact O-OG1 3.05Å; Y191-T194 PolarHBondContact O-N 3.15Å; T194-I196 VanDerWaalsContact C-N 3.29Å; T194-I196 PolarHBondContact O-N 3.32Å; T194-A197 PolarHBondContact O-N 3.43Å; T194-I198 HydrophobicContact CG2-CD1 3.58Å; T194-I198 HydrophobicContact CG2-CG1 4.25Å; T194-I198 VanDerWaalsContact O-CG1 3.27Å; T194-I198 WeakPolarHBondContact O-CG1 3.43Å; T194-I198 PolarHBondContact O-N 3.15Å; T194-I198 VanDerWaalsContact O-N 3.13Å; T194-L295 HydrophobicContact CG2-CD1 3.88Å; T194-Y321 HydrophobicContact CG2-CD1 4.49Å; T194-Y321 HydrophobicContact CG2-CD2 3.99Å; T194-Y321 HydrophobicContact CG2-CG 3.91Å
195	V	91.7	Very high	89	Confident	25 Å²	25	28 Å²	28	15%	0.152	15%	0.148	C	C	.	.	H	α-helix	trans	-63	-35.2	-177	171.9	0	0	0	0	112.3	Y191 F192 G193 P199 L322	Y191-V195 WeakPolarHBondContact O-CG2 3.11Å; Y191-V195 PolarHBondContact O-N 3.34Å; F192-V195 PolarHBondContact O-N 3.48Å; G193-V195 PolarHBondContact O-N 2.96Å; V195-P199 WeakPolarHBondContact O-CD 3.14Å; V195-P199 WeakPolarHBondContact O-CG 3.37Å; V195-L322 HydrophobicContact CG1-CB 4.04Å; V195-L322 HydrophobicContact CG1-CD1 4.24Å; V195-L322 HydrophobicContact CG2-CB 3.83Å
196	I	92.8	Very high	89.1	Confident	78 Å²	78	27.9 Å²	27.9	40%	0.4	15%	0.146	S	C	.	.	H	α-helix	trans	-81.5	-42.9	176.1	-68	-177.6	0	0	0	111.3	F192 G193 T194 I198 P199 V200	F192-I196 HydrophobicContact CD1-CD1 3.68Å; F192-I196 HydrophobicContact CD1-CG1 4.48Å; F192-I196 HydrophobicContact CE1-CD1 3.12Å; F192-I196 HydrophobicContact CE1-CG1 4.25Å; F192-I196 HydrophobicContact CE2-CD1 4.25Å; F192-I196 HydrophobicContact CG-CD1 4.46Å; F192-I196 HydrophobicContact CZ-CD1 3.46Å; F192-I196 VanDerWaalsContact CZ-CD1 3.46Å; F192-I196 HydrophobicContact CZ-CG1 4.43Å; F192-I196 PolarHBondContact O-N 3.11Å; G193-I196 PolarHBondContact O-N 3.4Å; T194-I196 VanDerWaalsContact C-N 3.29Å; T194-I196 PolarHBondContact O-N 3.32Å; I196-I198 PolarHBondContact O-N 2.95Å; I196-P199 VanDerWaalsContact O-CD 3.23Å; I196-P199 WeakPolarHBondContact O-CD 3.44Å; I196-P199 WeakPolarHBondContact O-CG 3.26Å; I196-V200 HydrophobicContact CG2-CG2 3.84Å; I196-V200 VanDerWaalsContact O-CB 3.27Å; I196-V200 WeakPolarHBondContact O-CB 3.5Å; I196-V200 WeakPolarHBondContact O-CG2 3.37Å; I196-V200 PolarHBondContact O-N 3.48Å; I196-V200 VanDerWaalsContact O-N 3.1Å
197	A	92.9	Very high	89.1	Confident	8 Å²	8	33.1 Å²	33.1	7%	0.066	17%	0.17	C	C	.	.	H	α-helix	trans	-66.6	-38.3	-170.8	0	0	0	0	0	113	A43 V46 N47 G193 T194 S201	A43-A197 VanDerWaalsContact CA-CB 3.46Å; A43-A197 HydrophobicContact CB-CB 3.49Å; A43-A197 VanDerWaalsContact CB-CB 3.49Å; V46-A197 HydrophobicContact CG2-CB 3.67Å; N47-A197 WeakPolarHBondContact OD1-CB 3.33Å; G193-A197 WeakPolarHBondContact O-CB 3.37Å; G193-A197 PolarHBondContact O-N 3.27Å; T194-A197 PolarHBondContact O-N 3.43Å; A197-S201 WeakPolarHBondContact O-CB 3.4Å; A197-S201 PolarHBondContact O-N 3.47Å; A197-S201 PolarHBondContact O-OG 3.36Å
198	I	92.2	Very high	89.3	Confident	1 Å²	1	33.5 Å²	33.5	1%	0.005	18%	0.18	C	C	.	.	H	α-helix	trans	-58.9	-58.7	178.5	-66.4	173.6	0	0	0	111.6	V46 I50 T194 I196 S201 A202 G314 Y321	V46-I198 HydrophobicContact CB-CG1 4.49Å; V46-I198 HydrophobicContact CG2-CG1 4.12Å; I50-I198 HydrophobicContact CD1-CG2 3.74Å; I50-I198 HydrophobicContact CG1-CB 4.46Å; I50-I198 HydrophobicContact CG1-CG2 3.85Å; T194-I198 HydrophobicContact CG2-CD1 3.58Å; T194-I198 HydrophobicContact CG2-CG1 4.25Å; T194-I198 VanDerWaalsContact O-CG1 3.27Å; T194-I198 WeakPolarHBondContact O-CG1 3.43Å; T194-I198 PolarHBondContact O-N 3.15Å; T194-I198 VanDerWaalsContact O-N 3.13Å; I196-I198 PolarHBondContact O-N 2.95Å; I198-S201 PolarHBondContact O-N 3.25Å; I198-A202 PolarHBondContact O-N 3.4Å; I198-G314 WeakPolarHBondContact CG2-O 3.48Å; I198-Y321 HydrophobicContact CD1-CD2 3.63Å; I198-Y321 HydrophobicContact CD1-CE2 3.74Å
199	P	92.8	Very high	89.5	Confident	19 Å²	19	33.4 Å²	33.4	12%	0.123	18%	0.176	C	C	.	.	H	α-helix	trans	-69	-37.6	-178.3	25.8	-33.6	0	0	0	112.2	V195 I196 S201 A202 L203 F315 A318	V195-P199 WeakPolarHBondContact O-CD 3.14Å; V195-P199 WeakPolarHBondContact O-CG 3.37Å; I196-P199 VanDerWaalsContact O-CD 3.23Å; I196-P199 WeakPolarHBondContact O-CD 3.44Å; I196-P199 WeakPolarHBondContact O-CG 3.26Å; P199-S201 VanDerWaalsContact C-N 3.31Å; P199-S201 PolarHBondContact O-N 2.77Å; P199-A202 PolarHBondContact O-N 2.81Å; P199-L203 WeakPolarHBondContact O-CG 3.46Å; P199-L203 PolarHBondContact O-N 3.46Å; P199-F315 HydrophobicContact CB-CD1 3.88Å; P199-F315 HydrophobicContact CB-CE1 4.01Å; P199-F315 HydrophobicContact CB-CG 4.25Å; P199-F315 HydrophobicContact CB-CZ 4.48Å; P199-A318 HydrophobicContact CG-CB 4.33Å
200	V	93.4	Very high	89.6	Confident	63 Å²	63	33.9 Å²	33.9	38%	0.382	18%	0.178	S	C	.	.	H	α-helix	trans	-62.7	-40.9	176.2	170.9	0	0	0	0	110.9	I196 A202 L203 I204	I196-V200 HydrophobicContact CG2-CG2 3.84Å; I196-V200 VanDerWaalsContact O-CB 3.27Å; I196-V200 WeakPolarHBondContact O-CB 3.5Å; I196-V200 WeakPolarHBondContact O-CG2 3.37Å; I196-V200 PolarHBondContact O-N 3.48Å; I196-V200 VanDerWaalsContact O-N 3.1Å; V200-A202 VanDerWaalsContact C-N 3.35Å; V200-L203 PolarHBondContact O-N 3.35Å; V200-I204 HydrophobicContact CG1-CD1 3.66Å; V200-I204 HydrophobicContact CG1-CG1 4.34Å; V200-I204 WeakPolarHBondContact O-CB 3.45Å; V200-I204 VanDerWaalsContact O-CG1 3.26Å; V200-I204 WeakPolarHBondContact O-CG1 3.43Å; V200-I204 PolarHBondContact O-N 3.06Å
201	S	93.2	Very high	89.9	Confident	2 Å²	2	34 Å²	34	1%	0.014	18%	0.178	C	C	.	.	H	α-helix	trans	-63.2	-41.6	175.3	-64.4	0	0	0	0	111.9	N47 A197 I198 P199 I204 A205 V213	N47-S201 PolarHBondContact OD1-OG 3.49Å; A197-S201 WeakPolarHBondContact O-CB 3.4Å; A197-S201 PolarHBondContact O-N 3.47Å; A197-S201 PolarHBondContact O-OG 3.36Å; I198-S201 PolarHBondContact O-N 3.25Å; P199-S201 VanDerWaalsContact C-N 3.31Å; P199-S201 PolarHBondContact O-N 2.77Å; S201-I204 PolarHBondContact O-N 2.87Å; S201-A205 WeakPolarHBondContact O-CB 3.32Å; S201-A205 PolarHBondContact O-N 2.69Å; S201-V213 WeakPolarHBondContact O-CG2 3.43Å; S201-V213 VanDerWaalsContact OG-CG1 3.23Å; S201-V213 WeakPolarHBondContact OG-CG1 3.33Å
202	A	91.2	Very high	90.3	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-64	-45.1	176.8	0	0	0	0	0	111.3	I50 Y54 I198 P199 V200 I204 A205 E206	I50-A202 HydrophobicContact CG2-CB 3.94Å; Y54-A202 PolarHBondContact OH-O 3.46Å; I198-A202 PolarHBondContact O-N 3.4Å; P199-A202 PolarHBondContact O-N 2.81Å; V200-A202 VanDerWaalsContact C-N 3.35Å; A202-I204 PolarHBondContact O-N 2.85Å; A202-A205 PolarHBondContact O-N 2.86Å; A202-E206 VanDerWaalsContact O-CB 3.24Å; A202-E206 WeakPolarHBondContact O-CB 2.81Å; A202-E206 PolarHBondContact O-N 3.39Å
203	L	91.4	Very high	90.6	Very high	57 Å²	57	30.2 Å²	30.2	30%	0.298	17%	0.166	S	C	.	.	H	α-helix	trans	-60.2	-45.9	176.4	-74.4	176.7	0	0	0	112.7	P199 V200 H207 Q311 F315	P199-L203 WeakPolarHBondContact O-CG 3.46Å; P199-L203 PolarHBondContact O-N 3.46Å; V200-L203 PolarHBondContact O-N 3.35Å; L203-H207 WeakPolarHBondContact O-CB 3.3Å; L203-H207 PolarHBondContact O-N 3.24Å; L203-H207 PolarHBondContact O-ND1 3.18Å; L203-Q311 HydrophobicContact CD2-CG 4.39Å; L203-F315 HydrophobicContact CD1-CE2 4.48Å; L203-F315 HydrophobicContact CD1-CZ 3.84Å; L203-F315 HydrophobicContact CD2-CE2 3.75Å; L203-F315 HydrophobicContact CD2-CZ 3.83Å; L203-F315 HydrophobicContact CG-CE2 3.98Å; L203-F315 HydrophobicContact CG-CZ 3.85Å
204	I	91.5	Very high	90.8	Very high	35 Å²	35	30.3 Å²	30.3	18%	0.179	17%	0.166	C	C	.	.	H	α-helix	trans	-66	-44.6	179.2	-68.4	169	0	0	0	110.6	V200 S201 A202 E206 S208 V212 V213 V216	V200-I204 HydrophobicContact CG1-CD1 3.66Å; V200-I204 HydrophobicContact CG1-CG1 4.34Å; V200-I204 WeakPolarHBondContact O-CB 3.45Å; V200-I204 VanDerWaalsContact O-CG1 3.26Å; V200-I204 WeakPolarHBondContact O-CG1 3.43Å; V200-I204 PolarHBondContact O-N 3.06Å; S201-I204 PolarHBondContact O-N 2.87Å; A202-I204 PolarHBondContact O-N 2.85Å; I204-E206 VanDerWaalsContact C-N 3.34Å; I204-E206 PolarHBondContact O-N 3.44Å; I204-S208 WeakPolarHBondContact O-CA 3.4Å; I204-S208 VanDerWaalsContact O-CB 3.32Å; I204-S208 WeakPolarHBondContact O-CB 3.43Å; I204-S208 PolarHBondContact O-N 3.39Å; I204-V212 HydrophobicContact CG2-CB 3.75Å; I204-V212 HydrophobicContact CG2-CG1 3.69Å; I204-V213 HydrophobicContact CB-CG2 4.01Å; I204-V213 HydrophobicContact CG2-CG2 3.75Å; I204-V216 HydrophobicContact CD1-CB 4.45Å; I204-V216 HydrophobicContact CD1-CG1 4.29Å; I204-V216 HydrophobicContact CD1-CG2 4.4Å
205	A	87.8	Confident	91.1	Very high	7 Å²	7	34.3 Å²	34.3	6%	0.058	18%	0.181	C	C	.	.	H	α-helix	trans	-64.4	-39.5	-179.4	0	0	0	0	0	112.1	Y54 S201 A202 W210 V213	Y54-A205 HydrophobicContact CD1-CB 4.02Å; Y54-A205 HydrophobicContact CD2-CB 3.57Å; Y54-A205 HydrophobicContact CE1-CB 4.06Å; Y54-A205 HydrophobicContact CE2-CB 3.64Å; Y54-A205 HydrophobicContact CG-CB 3.77Å; S201-A205 WeakPolarHBondContact O-CB 3.32Å; S201-A205 PolarHBondContact O-N 2.69Å; A202-A205 PolarHBondContact O-N 2.86Å; A205-W210 HydrophobicContact CB-CB 4.46Å; A205-V213 HydrophobicContact CB-CG2 4.08Å
206	E	85.3	Confident	91.3	Very high	64 Å²	64	35.5 Å²	35.5	30%	0.299	19%	0.188	S	C	.	.	H	α-helix	trans	-67.7	-50.4	177.5	-173.6	65.9	-143.7	0	0	112.3	Y54 A202 I204 Q311	Y54-E206 HydrophobicContact CE1-CB 4.29Å; Y54-E206 WeakPolarHBondContact CE1-OE2 3.47Å; Y54-E206 PolarHBondContact OH-OE2 3.25Å; A202-E206 VanDerWaalsContact O-CB 3.24Å; A202-E206 WeakPolarHBondContact O-CB 2.81Å; A202-E206 PolarHBondContact O-N 3.39Å; I204-E206 VanDerWaalsContact C-N 3.34Å; I204-E206 PolarHBondContact O-N 3.44Å; E206-Q311 HydrophobicContact CG-CB 4.26Å; E206-Q311 HydrophobicContact CG-CG 4.45Å
207	H	85.9	Confident	91.3	Very high	110 Å²	110	32.2 Å²	32.2	51%	0.509	17%	0.172	S	C	.	.	H	α-helix	trans	-82	-24.7	-172.8	-67.9	80	0	0	0	113.4	R61 L203	R61-H207 PolarHBondContact NH2-O 3.46Å; L203-H207 WeakPolarHBondContact O-CB 3.3Å; L203-H207 PolarHBondContact O-N 3.24Å; L203-H207 PolarHBondContact O-ND1 3.18Å
208	S	84.9	Confident	91.4	Very high	59 Å²	59	31.8 Å²	31.8	41%	0.413	17%	0.169	S	C	.	.	S	Bend	trans	-120.4	-110.6	-174.6	-59.8	0	0	0	0	111.5	R72 I204	R72-S208 PolarHBondContact NH1-O 3.11Å; I204-S208 WeakPolarHBondContact O-CA 3.4Å; I204-S208 VanDerWaalsContact O-CB 3.32Å; I204-S208 WeakPolarHBondContact O-CB 3.43Å; I204-S208 PolarHBondContact O-N 3.39Å
209	H	87.4	Confident	91.6	Very high	31 Å²	31	36.2 Å²	36.2	14%	0.144	19%	0.192	C	C	.	.			trans	-144.2	143.5	177.6	-175.6	-94.4	0	0	0	106.8	R72 E75 F130 S211 V212	R72-H209 PolarHBondContact NH1-CD2 3.38Å; E75-H209 IonicContact OE1-CE1 3.95Å; E75-H209 IonicContact OE1-NE2 3.36Å; E75-H209 PolarHBondContact OE1-NE2 2.85Å; F130-H209 AromaticContact CE2-CE1 3.75Å; H209-S211 VanDerWaalsContact ND1-CB 3.35Å; H209-S211 WeakPolarHBondContact ND1-CB 3.19Å; H209-S211 PolarHBondContact ND1-N 3.04Å; H209-S211 VanDerWaalsContact ND1-N 3.19Å; H209-S211 PolarHBondContact ND1-OG 3.13Å; H209-S211 PolarHBondContact O-N 2.97Å; H209-V212 HydrophobicContact CB-CG2 4.25Å; H209-V212 VanDerWaalsContact O-CB 3.31Å; H209-V212 WeakPolarHBondContact O-CB 3.33Å; H209-V212 WeakPolarHBondContact O-CG2 3.31Å; H209-V212 PolarHBondContact O-N 2.9Å
210	W	89.3	Confident	91.7	Very high	11 Å²	11	41.3 Å²	41.3	4%	0.042	21%	0.213	C	C	.	.	H	α-helix	trans	-56.1	-29.7	-176	63.5	-99	0	0	0	112.6	M55 F130 A133 A205 V212 V213 F214	M55-W210 HydrophobicContact CE-CH2 4.03Å; M55-W210 HydrophobicContact CE-CZ2 4.48Å; M55-W210 HydrophobicContact CE-CZ3 4.12Å; M55-W210 HydrophobicContact CG-CD2 3.52Å; M55-W210 HydrophobicContact CG-CE3 3.74Å; M55-W210 HydrophobicContact CG-CG 3.91Å; M55-W210 HydrophobicContact CG-CH2 4.33Å; M55-W210 HydrophobicContact CG-CZ2 4.17Å; M55-W210 HydrophobicContact CG-CZ3 4.15Å; M55-W210 HydrophobicContact SD-CD2 4.27Å; M55-W210 HydrophobicContact SD-CE3 3.85Å; M55-W210 HydrophobicContact SD-CH2 4.32Å; M55-W210 HydrophobicContact SD-CZ3 3.88Å; F130-W210 AromaticContact CD2-CH2 3.56Å; F130-W210 HydrophobicContact CD2-CH2 3.56Å; F130-W210 AromaticContact CD2-CZ2 3.68Å; F130-W210 HydrophobicContact CD2-CZ2 3.68Å; F130-W210 HydrophobicContact CD2-CZ3 4.28Å; F130-W210 HydrophobicContact CE2-CH2 4.28Å; F130-W210 AromaticContact CE2-CZ2 3.94Å; F130-W210 HydrophobicContact CE2-CZ2 3.94Å; A133-W210 HydrophobicContact CB-CH2 3.79Å; A205-W210 HydrophobicContact CB-CB 4.46Å; W210-V212 VanDerWaalsContact C-N 3.26Å; W210-V212 PolarHBondContact O-N 3.46Å; W210-V213 VanDerWaalsContact O-CB 3.29Å; W210-V213 WeakPolarHBondContact O-CB 3.5Å; W210-V213 WeakPolarHBondContact O-CG2 3.44Å; W210-V213 PolarHBondContact O-N 3.26Å; W210-F214 HydrophobicContact CE3-CD2 4.02Å; W210-F214 AromaticContact CE3-CE2 3.71Å; W210-F214 HydrophobicContact CE3-CE2 3.71Å; W210-F214 HydrophobicContact CZ3-CD2 4Å; W210-F214 AromaticContact CZ3-CE2 3.78Å; W210-F214 HydrophobicContact CZ3-CE2 3.78Å
211	S	92	Very high	91.7	Very high	8 Å²	8	38.3 Å²	38.3	6%	0.056	20%	0.195	C	C	.	.	H	α-helix	trans	-63.6	-29.8	177.5	67.7	0	0	0	0	113.6	F130 H209 V213 F214 Y215	F130-S211 VanDerWaalsContact CD2-CB 3.41Å; H209-S211 VanDerWaalsContact ND1-CB 3.35Å; H209-S211 WeakPolarHBondContact ND1-CB 3.19Å; H209-S211 PolarHBondContact ND1-N 3.04Å; H209-S211 VanDerWaalsContact ND1-N 3.19Å; H209-S211 PolarHBondContact ND1-OG 3.13Å; H209-S211 PolarHBondContact O-N 2.97Å; S211-V213 PolarHBondContact O-N 3.25Å; S211-F214 PolarHBondContact O-N 2.72Å; S211-Y215 PolarHBondContact O-N 3.05Å
212	V	93.5	Very high	91.9	Very high	47 Å²	47	40.4 Å²	40.4	29%	0.285	21%	0.205	S	C	.	.	H	α-helix	trans	-62.5	-30.1	179.6	-178.5	0	0	0	0	110.7	I204 H209 W210 F214 Y215 V216	I204-V212 HydrophobicContact CG2-CB 3.75Å; I204-V212 HydrophobicContact CG2-CG1 3.69Å; H209-V212 HydrophobicContact CB-CG2 4.25Å; H209-V212 VanDerWaalsContact O-CB 3.31Å; H209-V212 WeakPolarHBondContact O-CB 3.33Å; H209-V212 WeakPolarHBondContact O-CG2 3.31Å; H209-V212 PolarHBondContact O-N 2.9Å; W210-V212 VanDerWaalsContact C-N 3.26Å; W210-V212 PolarHBondContact O-N 3.46Å; V212-F214 VanDerWaalsContact C-N 3.25Å; V212-F214 PolarHBondContact O-N 3.09Å; V212-Y215 PolarHBondContact O-N 3.27Å; V212-V216 HydrophobicContact CG1-CG2 3.89Å; V212-V216 WeakPolarHBondContact O-CB 3.48Å; V212-V216 VanDerWaalsContact O-CG2 3.27Å; V212-V216 WeakPolarHBondContact O-CG2 3.3Å; V212-V216 PolarHBondContact O-N 3.27Å
213	V	93.9	Very high	92.1	Very high	2 Å²	2	44.8 Å²	44.8	1%	0.012	23%	0.228	C	C	.	.	H	α-helix	trans	-56.6	-42.2	174.9	-177.4	0	0	0	0	111.1	N47 S201 I204 A205 W210 S211 S217	N47-V213 HydrophobicContact CB-CG1 3.69Å; S201-V213 WeakPolarHBondContact O-CG2 3.43Å; S201-V213 VanDerWaalsContact OG-CG1 3.23Å; S201-V213 WeakPolarHBondContact OG-CG1 3.33Å; I204-V213 HydrophobicContact CB-CG2 4.01Å; I204-V213 HydrophobicContact CG2-CG2 3.75Å; A205-V213 HydrophobicContact CB-CG2 4.08Å; W210-V213 VanDerWaalsContact O-CB 3.29Å; W210-V213 WeakPolarHBondContact O-CB 3.5Å; W210-V213 WeakPolarHBondContact O-CG2 3.44Å; W210-V213 PolarHBondContact O-N 3.26Å; S211-V213 PolarHBondContact O-N 3.25Å; V213-S217 WeakPolarHBondContact O-CB 3.48Å; V213-S217 PolarHBondContact O-N 3.13Å; V213-S217 VanDerWaalsContact O-N 3.11Å; V213-S217 PolarHBondContact O-OG 3.09Å
214	F	95.1	Very high	92.3	Very high	7 Å²	7	42.8 Å²	42.8	3%	0.031	22%	0.217	C	C	.	.	H	α-helix	trans	-77.3	-35.9	-179.9	-60.6	-67.7	0	0	0	112.4	N47 L48 A51 A126 T129 W210 S211 V212 S217 G218	N47-F214 HydrophobicContact CB-CE1 4.39Å; L48-F214 HydrophobicContact CB-CE1 4.29Å; L48-F214 HydrophobicContact CB-CZ 4.27Å; L48-F214 HydrophobicContact CD1-CE1 4.46Å; L48-F214 HydrophobicContact CD1-CZ 3.77Å; A51-F214 HydrophobicContact CB-CE2 3.75Å; A51-F214 HydrophobicContact CB-CZ 3.67Å; A126-F214 WeakPolarHBondContact O-CB 3.46Å; T129-F214 HydrophobicContact CG2-CB 4.42Å; T129-F214 HydrophobicContact CG2-CD1 3.85Å; T129-F214 HydrophobicContact CG2-CD2 3.6Å; T129-F214 HydrophobicContact CG2-CE1 3.94Å; T129-F214 HydrophobicContact CG2-CE2 3.68Å; T129-F214 HydrophobicContact CG2-CG 3.69Å; T129-F214 HydrophobicContact CG2-CZ 3.85Å; W210-F214 HydrophobicContact CE3-CD2 4.02Å; W210-F214 AromaticContact CE3-CE2 3.71Å; W210-F214 HydrophobicContact CE3-CE2 3.71Å; W210-F214 HydrophobicContact CZ3-CD2 4Å; W210-F214 AromaticContact CZ3-CE2 3.78Å; W210-F214 HydrophobicContact CZ3-CE2 3.78Å; S211-F214 PolarHBondContact O-N 2.72Å; V212-F214 VanDerWaalsContact C-N 3.25Å; V212-F214 PolarHBondContact O-N 3.09Å; F214-S217 PolarHBondContact O-OG 2.95Å; F214-G218 WeakPolarHBondContact O-CA 3.46Å; F214-G218 PolarHBondContact O-N 2.88Å
215	Y	95.5	Very high	92.4	Very high	87 Å²	87	41.6 Å²	41.6	34%	0.341	21%	0.211	S	C	.	.	H	α-helix	trans	-64.2	-45.7	174	-61.6	-35.6	0	0	0	112.2	L127 F130 S211 V212 L219	L127-Y215 HydrophobicContact CD2-CD1 4.09Å; L127-Y215 WeakPolarHBondContact O-CE1 3.41Å; F130-Y215 HydrophobicContact CB-CE1 4.43Å; F130-Y215 WeakPolarHBondContact CB-OH 3.24Å; F130-Y215 VanDerWaalsContact CD1-OH 3.3Å; F130-Y215 WeakPolarHBondContact CD1-OH 3.4Å; S211-Y215 PolarHBondContact O-N 3.05Å; V212-Y215 PolarHBondContact O-N 3.27Å; Y215-L219 WeakPolarHBondContact O-CB 3.37Å; Y215-L219 PolarHBondContact O-N 3.5Å
216	V	94.9	Very high	92.8	Very high	49 Å²	49	46 Å²	46	30%	0.297	23%	0.233	S	C	.	.	H	α-helix	trans	-63	-54.9	178.4	171	0	0	0	0	110.3	I204 V212 G218 L219 F220	I204-V216 HydrophobicContact CD1-CB 4.45Å; I204-V216 HydrophobicContact CD1-CG1 4.29Å; I204-V216 HydrophobicContact CD1-CG2 4.4Å; V212-V216 HydrophobicContact CG1-CG2 3.89Å; V212-V216 WeakPolarHBondContact O-CB 3.48Å; V212-V216 VanDerWaalsContact O-CG2 3.27Å; V212-V216 WeakPolarHBondContact O-CG2 3.3Å; V212-V216 PolarHBondContact O-N 3.27Å; V216-G218 VanDerWaalsContact C-N 3.33Å; V216-G218 PolarHBondContact O-N 3.06Å; V216-L219 PolarHBondContact O-N 3.41Å; V216-F220 HydrophobicContact CG1-CD2 3.72Å; V216-F220 HydrophobicContact CG1-CE2 3.66Å; V216-F220 WeakPolarHBondContact O-CD2 3.35Å; V216-F220 PolarHBondContact O-N 3.43Å
217	S	93.7	Very high	93.2	Very high	9 Å²	9	46.9 Å²	46.9	6%	0.063	24%	0.24	C	C	.	.	H	α-helix	trans	-64.5	-36.9	-178.8	53.2	0	0	0	0	113.1	N47 V213 F214 G221	N47-S217 WeakPolarHBondContact ND2-CB 3.28Å; N47-S217 PolarHBondContact ND2-OG 3.03Å; N47-S217 VanDerWaalsContact ND2-OG 3.12Å; V213-S217 WeakPolarHBondContact O-CB 3.48Å; V213-S217 PolarHBondContact O-N 3.13Å; V213-S217 VanDerWaalsContact O-N 3.11Å; V213-S217 PolarHBondContact O-OG 3.09Å; F214-S217 PolarHBondContact O-OG 2.95Å; S217-G221 PolarHBondContact O-N 2.82Å
218	G	95	Very high	93.6	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-64.2	-45.8	174.7	0	0	0	0	0	112.9	G123 F214 V216 G221 I222	G123-G218 WeakPolarHBondContact O-CA 2.98Å; F214-G218 WeakPolarHBondContact O-CA 3.46Å; F214-G218 PolarHBondContact O-N 2.88Å; V216-G218 VanDerWaalsContact C-N 3.33Å; V216-G218 PolarHBondContact O-N 3.06Å; G218-G221 PolarHBondContact O-N 3.43Å; G218-I222 WeakPolarHBondContact O-CG1 3.31Å; G218-I222 PolarHBondContact O-N 3.22Å
219	L	96.1	Very high	93.8	Very high	94 Å²	94	40.8 Å²	40.8	49%	0.492	21%	0.205	S	C	.	.	H	α-helix	trans	-63.1	-44.1	177.4	-176.7	62.4	0	0	0	111.5	Y215 V216 G221 I222 L223	Y215-L219 WeakPolarHBondContact O-CB 3.37Å; Y215-L219 PolarHBondContact O-N 3.5Å; V216-L219 PolarHBondContact O-N 3.41Å; L219-G221 VanDerWaalsContact C-N 3.3Å; L219-G221 PolarHBondContact O-N 3.23Å; L219-I222 PolarHBondContact O-N 2.8Å; L219-L223 HydrophobicContact CD1-CD1 4.31Å; L219-L223 HydrophobicContact CD1-CG 4.21Å; L219-L223 HydrophobicContact CG-CD1 3.98Å; L219-L223 HydrophobicContact CG-CG 4.31Å; L219-L223 WeakPolarHBondContact O-CB 3.32Å; L219-L223 VanDerWaalsContact O-CG 3.32Å; L219-L223 WeakPolarHBondContact O-CG 3.48Å; L219-L223 PolarHBondContact O-N 3.11Å
220	F	95.4	Very high	94	Very high	126 Å²	126	46.4 Å²	46.4	55%	0.553	24%	0.236	S	C	*	.	H	α-helix	trans	-59.2	-40.4	173.6	-84.8	-68.6	0	0	0	112.1	I40 V216 W224	I40-F220 HydrophobicContact CD1-CB 4.47Å; V216-F220 HydrophobicContact CG1-CD2 3.72Å; V216-F220 HydrophobicContact CG1-CE2 3.66Å; V216-F220 WeakPolarHBondContact O-CD2 3.35Å; V216-F220 PolarHBondContact O-N 3.43Å; F220-W224 WeakPolarHBondContact O-CB 3.09Å; F220-W224 PolarHBondContact O-N 2.68Å
221	G	93.9	Very high	94	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-61	-42.9	174.4	0	0	0	0	0	113.5	S217 G218 L219 S225	S217-G221 PolarHBondContact O-N 2.82Å; G218-G221 PolarHBondContact O-N 3.43Å; L219-G221 VanDerWaalsContact C-N 3.3Å; L219-G221 PolarHBondContact O-N 3.23Å; G221-S225 WeakPolarHBondContact O-CB 3.18Å; G221-S225 PolarHBondContact O-N 3.46Å
222	I	95.5	Very high	93.8	Very high	46 Å²	46	47.2 Å²	47.2	24%	0.236	24%	0.241	C	C	.	.	H	α-helix	trans	-67.5	-50.3	177.7	-65.4	165.3	0	0	0	110.8	A124 L127 G218 L219 W224 S225 L226	A124-I222 HydrophobicContact CB-CD1 4.36Å; L127-I222 HydrophobicContact CD1-CD1 3.69Å; L127-I222 HydrophobicContact CG-CD1 4.33Å; G218-I222 WeakPolarHBondContact O-CG1 3.31Å; G218-I222 PolarHBondContact O-N 3.22Å; L219-I222 PolarHBondContact O-N 2.8Å; I222-W224 VanDerWaalsContact C-N 3.31Å; I222-W224 PolarHBondContact O-N 2.99Å; I222-S225 WeakPolarHBondContact O-CB 3.27Å; I222-S225 PolarHBondContact O-N 3.39Å; I222-S225 VanDerWaalsContact O-N 3.12Å; I222-L226 HydrophobicContact CG2-CD1 4.23Å; I222-L226 WeakPolarHBondContact O-CG 3.23Å; I222-L226 PolarHBondContact O-N 3.22Å
223	L	96.9	Very high	93.4	Very high	92 Å²	92	45.6 Å²	45.6	48%	0.482	23%	0.233	S	C	.	.	H	α-helix	trans	-60	-42.7	179.6	-69.8	176	0	0	0	111.5	L219 L226 L227	L219-L223 HydrophobicContact CD1-CD1 4.31Å; L219-L223 HydrophobicContact CD1-CG 4.21Å; L219-L223 HydrophobicContact CG-CD1 3.98Å; L219-L223 HydrophobicContact CG-CG 4.31Å; L219-L223 WeakPolarHBondContact O-CB 3.32Å; L219-L223 VanDerWaalsContact O-CG 3.32Å; L219-L223 WeakPolarHBondContact O-CG 3.48Å; L219-L223 PolarHBondContact O-N 3.11Å; L223-L226 PolarHBondContact O-N 3.31Å; L223-L227 WeakPolarHBondContact O-CB 3.4Å; L223-L227 PolarHBondContact O-N 3.39Å
224	W	95.9	Very high	92.6	Very high	15 Å²	15	46.9 Å²	46.9	6%	0.057	24%	0.24	C	C	.	.	H	α-helix	trans	-63.2	-42.2	174.9	-179.1	94	0	0	0	111.9	I33 I40 L115 I119 F220 I222 L226 L227 W228	I33-W224 HydrophobicContact CG1-CZ2 4.48Å; I33-W224 WeakPolarHBondContact O-CZ2 3.37Å; I33-W224 PolarHBondContact O-NE1 2.99Å; I40-W224 HydrophobicContact CD1-CB 3.57Å; I40-W224 HydrophobicContact CD1-CG 3.71Å; L115-W224 HydrophobicContact CD1-CH2 3.77Å; L115-W224 HydrophobicContact CD1-CZ3 4.25Å; L115-W224 HydrophobicContact CD2-CH2 4.11Å; L115-W224 HydrophobicContact CG-CH2 3.71Å; L115-W224 HydrophobicContact CG-CZ3 4.31Å; I119-W224 HydrophobicContact CB-CE3 4Å; I119-W224 HydrophobicContact CB-CZ3 3.94Å; I119-W224 HydrophobicContact CD1-CE3 3.87Å; I119-W224 HydrophobicContact CD1-CH2 3.79Å; I119-W224 HydrophobicContact CD1-CZ3 3.42Å; I119-W224 VanDerWaalsContact CD1-CZ3 3.42Å; I119-W224 HydrophobicContact CG1-CZ3 4.17Å; I119-W224 HydrophobicContact CG2-CE3 3.72Å; I119-W224 HydrophobicContact CG2-CZ3 4.17Å; F220-W224 WeakPolarHBondContact O-CB 3.09Å; F220-W224 PolarHBondContact O-N 2.68Å; I222-W224 VanDerWaalsContact C-N 3.31Å; I222-W224 PolarHBondContact O-N 2.99Å; W224-L226 PolarHBondContact O-N 2.97Å; W224-L227 PolarHBondContact O-N 3.26Å; W224-W228 HydrophobicContact CD2-CB 4.47Å; W224-W228 HydrophobicContact CE3-CB 4.23Å; W224-W228 HydrophobicContact CH2-CB 3.93Å; W224-W228 AromaticContact CH2-CD2 3.6Å; W224-W228 HydrophobicContact CH2-CD2 3.6Å; W224-W228 AromaticContact CH2-CE3 3.58Å; W224-W228 HydrophobicContact CH2-CE3 3.58Å; W224-W228 AromaticContact CH2-CG 3.73Å; W224-W228 HydrophobicContact CH2-CG 3.73Å; W224-W228 HydrophobicContact CH2-CZ3 4.34Å; W224-W228 HydrophobicContact CZ2-CB 4.22Å; W224-W228 AromaticContact CZ2-CD2 3.94Å; W224-W228 HydrophobicContact CZ2-CD2 3.94Å; W224-W228 AromaticContact CZ2-CE3 3.43Å; W224-W228 HydrophobicContact CZ2-CE3 3.43Å; W224-W228 VanDerWaalsContact CZ2-CE3 3.43Å; W224-W228 HydrophobicContact CZ2-CG 4.26Å; W224-W228 HydrophobicContact CZ2-CZ3 4.13Å; W224-W228 HydrophobicContact CZ3-CB 3.93Å; W224-W228 HydrophobicContact CZ3-CD2 4.36Å; W224-W228 HydrophobicContact CZ3-CG 4.02Å; W224-W228 VanDerWaalsContact O-CB 3.26Å; W224-W228 WeakPolarHBondContact O-CB 3.32Å; W224-W228 PolarHBondContact O-N 3.33Å
225	S	93.3	Very high	91.9	Very high	9 Å²	9	47.2 Å²	47.2	6%	0.063	24%	0.243	C	C	.	.	H	α-helix	trans	-61.5	-44.3	176.9	173.3	0	0	0	0	111.7	G116 G221 I222 W228 M229	G116-S225 WeakPolarHBondContact O-CB 3.49Å; G116-S225 PolarHBondContact O-OG 3.37Å; G221-S225 WeakPolarHBondContact O-CB 3.18Å; G221-S225 PolarHBondContact O-N 3.46Å; I222-S225 WeakPolarHBondContact O-CB 3.27Å; I222-S225 PolarHBondContact O-N 3.39Å; I222-S225 VanDerWaalsContact O-N 3.12Å; S225-W228 PolarHBondContact O-N 2.9Å; S225-M229 WeakPolarHBondContact O-CB 2.97Å; S225-M229 WeakPolarHBondContact O-CG 3.45Å; S225-M229 PolarHBondContact O-N 2.97Å
226	L	94.9	Very high	91.1	Very high	100 Å²	100	43.2 Å²	43.2	52%	0.524	23%	0.227	S	C	.	.	H	α-helix	trans	-60.5	-49.1	174.9	-68.5	174.3	0	0	0	110.9	I222 L223 W224 W228 M229 L230	I222-L226 HydrophobicContact CG2-CD1 4.23Å; I222-L226 WeakPolarHBondContact O-CG 3.23Å; I222-L226 PolarHBondContact O-N 3.22Å; L223-L226 PolarHBondContact O-N 3.31Å; W224-L226 PolarHBondContact O-N 2.97Å; L226-W228 PolarHBondContact O-N 3.4Å; L226-M229 PolarHBondContact O-N 3.49Å; L226-L230 WeakPolarHBondContact O-CB 3.33Å; L226-L230 VanDerWaalsContact O-CG 3.24Å; L226-L230 WeakPolarHBondContact O-CG 3.39Å; L226-L230 PolarHBondContact O-N 3.39Å
227	L	95.1	Very high	90.4	Very high	83 Å²	83	44.5 Å²	44.5	44%	0.435	24%	0.239	S	C	.	.	H	α-helix	trans	-57.2	-50.5	177.1	-177.2	66	0	0	0	111.1	I33 L223 W224 M229 L230 T231	I33-L227 HydrophobicContact CD1-CD2 4.01Å; I33-L227 HydrophobicContact CD1-CG 3.94Å; L223-L227 WeakPolarHBondContact O-CB 3.4Å; L223-L227 PolarHBondContact O-N 3.39Å; W224-L227 PolarHBondContact O-N 3.26Å; L227-M229 VanDerWaalsContact C-N 3.33Å; L227-M229 PolarHBondContact O-N 2.92Å; L227-L230 PolarHBondContact O-N 3.01Å; L227-L230 VanDerWaalsContact O-N 3.14Å; L227-T231 HydrophobicContact CD1-CG2 3.66Å; L227-T231 HydrophobicContact CG-CG2 4.26Å; L227-T231 WeakPolarHBondContact O-CB 3.46Å; L227-T231 WeakPolarHBondContact O-CG2 3.41Å; L227-T231 PolarHBondContact O-N 2.97Å; L227-T231 PolarHBondContact O-OG1 3.42Å
228	W	92.8	Very high	89.8	Confident	0 Å²	0	51.4 Å²	51.4	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-56	-45.6	178.5	175.1	-90.8	0	0	0	112.2	L30 I33 A34 R112 L115 L169 W224 S225 L226 L230 T231 V232	L30-W228 HydrophobicContact CD1-CH2 3.52Å; L30-W228 HydrophobicContact CD1-CZ2 4.42Å; L30-W228 HydrophobicContact CD1-CZ3 3.8Å; I33-W228 HydrophobicContact CD1-CB 4.48Å; I33-W228 HydrophobicContact CD1-CE3 4.25Å; I33-W228 HydrophobicContact CG1-CE3 4.16Å; I33-W228 HydrophobicContact CG2-CE3 3.84Å; I33-W228 HydrophobicContact CG2-CZ3 3.71Å; A34-W228 HydrophobicContact CB-CH2 4.41Å; A34-W228 HydrophobicContact CB-CZ3 4.02Å; R112-W228 HydrophobicContact CG-CZ2 4.38Å; R112-W228 PolarHBondContact O-NE1 2.96Å; L115-W228 HydrophobicContact CB-CZ2 4.48Å; L115-W228 HydrophobicContact CD2-CD2 4.4Å; L115-W228 HydrophobicContact CD2-CE3 4.43Å; L115-W228 HydrophobicContact CD2-CH2 3.5Å; L115-W228 VanDerWaalsContact CD2-CH2 3.5Å; L115-W228 HydrophobicContact CD2-CZ2 3.45Å; L115-W228 VanDerWaalsContact CD2-CZ2 3.45Å; L115-W228 HydrophobicContact CD2-CZ3 3.98Å; L115-W228 HydrophobicContact CG-CZ2 4.13Å; L169-W228 HydrophobicContact CD1-CH2 4.05Å; L169-W228 HydrophobicContact CD1-CZ2 3.65Å; W224-W228 HydrophobicContact CD2-CB 4.47Å; W224-W228 HydrophobicContact CE3-CB 4.23Å; W224-W228 HydrophobicContact CH2-CB 3.93Å; W224-W228 AromaticContact CH2-CD2 3.6Å; W224-W228 HydrophobicContact CH2-CD2 3.6Å; W224-W228 AromaticContact CH2-CE3 3.58Å; W224-W228 HydrophobicContact CH2-CE3 3.58Å; W224-W228 AromaticContact CH2-CG 3.73Å; W224-W228 HydrophobicContact CH2-CG 3.73Å; W224-W228 HydrophobicContact CH2-CZ3 4.34Å; W224-W228 HydrophobicContact CZ2-CB 4.22Å; W224-W228 AromaticContact CZ2-CD2 3.94Å; W224-W228 HydrophobicContact CZ2-CD2 3.94Å; W224-W228 AromaticContact CZ2-CE3 3.43Å; W224-W228 HydrophobicContact CZ2-CE3 3.43Å; W224-W228 VanDerWaalsContact CZ2-CE3 3.43Å; W224-W228 HydrophobicContact CZ2-CG 4.26Å; W224-W228 HydrophobicContact CZ2-CZ3 4.13Å; W224-W228 HydrophobicContact CZ3-CB 3.93Å; W224-W228 HydrophobicContact CZ3-CD2 4.36Å; W224-W228 HydrophobicContact CZ3-CG 4.02Å; W224-W228 VanDerWaalsContact O-CB 3.26Å; W224-W228 WeakPolarHBondContact O-CB 3.32Å; W224-W228 PolarHBondContact O-N 3.33Å; S225-W228 PolarHBondContact O-N 2.9Å; L226-W228 PolarHBondContact O-N 3.4Å; W228-L230 VanDerWaalsContact C-N 3.31Å; W228-L230 PolarHBondContact O-N 3.39Å; W228-T231 PolarHBondContact O-N 3.48Å; W228-V232 HydrophobicContact CD2-CB 4.21Å; W228-V232 HydrophobicContact CD2-CG2 3.81Å; W228-V232 HydrophobicContact CE3-CB 4.48Å; W228-V232 HydrophobicContact CE3-CG2 3.63Å; W228-V232 HydrophobicContact CG-CG2 4.45Å; W228-V232 HydrophobicContact CH2-CG1 4.06Å; W228-V232 HydrophobicContact CH2-CG2 4.13Å; W228-V232 HydrophobicContact CZ2-CB 4.25Å; W228-V232 HydrophobicContact CZ2-CG1 3.8Å; W228-V232 HydrophobicContact CZ2-CG2 4.27Å; W228-V232 HydrophobicContact CZ3-CG2 3.83Å; W228-V232 WeakPolarHBondContact O-CB 3.46Å; W228-V232 PolarHBondContact O-N 3.08Å
229	M	90.4	Very high	89.3	Confident	41 Å²	41	52.2 Å²	52.2	20%	0.202	27%	0.272	C	S	.	.	H	α-helix	trans	-69.1	-28.4	-179.6	-70.5	-63.3	-70.1	0	0	113.1	R112 R113 F117 S225 L226 L227	R112-M229 PolarHBondContact NH1-O 3.45Å; R113-M229 HydrophobicContact CG-CE 4.27Å; F117-M229 HydrophobicContact CE1-CE 3.92Å; F117-M229 HydrophobicContact CE2-CE 3.96Å; F117-M229 HydrophobicContact CZ-CE 3.56Å; S225-M229 WeakPolarHBondContact O-CB 2.97Å; S225-M229 WeakPolarHBondContact O-CG 3.45Å; S225-M229 PolarHBondContact O-N 2.97Å; L226-M229 PolarHBondContact O-N 3.49Å; L227-M229 VanDerWaalsContact C-N 3.33Å; L227-M229 PolarHBondContact O-N 2.92Å
230	L	91.3	Very high	88.6	Confident	149 Å²	149	57.7 Å²	57.7	78%	0.78	29%	0.292	S	S	*	.	H	α-helix	trans	-84.1	-33.8	176.6	-67.1	173.3	0	0	0	112.7	L226 L227 W228	L226-L230 WeakPolarHBondContact O-CB 3.33Å; L226-L230 VanDerWaalsContact O-CG 3.24Å; L226-L230 WeakPolarHBondContact O-CG 3.39Å; L226-L230 PolarHBondContact O-N 3.39Å; L227-L230 PolarHBondContact O-N 3.01Å; L227-L230 VanDerWaalsContact O-N 3.14Å; W228-L230 VanDerWaalsContact C-N 3.31Å; W228-L230 PolarHBondContact O-N 3.39Å
231	T	89.1	Confident	88.2	Confident	27 Å²	27	58.8 Å²	58.8	17%	0.166	30%	0.296	C	S	.	.	H	α-helix	trans	-102	-26.7	-169.7	63.1	0	0	0	0	115	R26 Y29 I33 L227 W228	R26-T231 PolarHBondContact NH2-O 2.83Å; Y29-T231 WeakPolarHBondContact OH-CB 3.46Å; Y29-T231 PolarHBondContact OH-OG1 3.48Å; I33-T231 WeakPolarHBondContact CD1-OG1 3.21Å; L227-T231 HydrophobicContact CD1-CG2 3.66Å; L227-T231 HydrophobicContact CG-CG2 4.26Å; L227-T231 WeakPolarHBondContact O-CB 3.46Å; L227-T231 WeakPolarHBondContact O-CG2 3.41Å; L227-T231 PolarHBondContact O-N 2.97Å; L227-T231 PolarHBondContact O-OG1 3.42Å; W228-T231 PolarHBondContact O-N 3.48Å
232	V	88.9	Confident	87.8	Confident	8 Å²	8	59.7 Å²	59.7	5%	0.048	30%	0.301	C	S	.	.			trans	-96.1	145.6	-176.5	179.2	0	0	0	0	110	L30 I33 R112 W228	L30-V232 HydrophobicContact CD1-CB 4.29Å; L30-V232 HydrophobicContact CD1-CG1 3.5Å; L30-V232 VanDerWaalsContact CD1-CG1 3.5Å; L30-V232 HydrophobicContact CD1-CG2 3.75Å; I33-V232 HydrophobicContact CG2-CG2 4.11Å; R112-V232 WeakPolarHBondContact CD-O 3.19Å; R112-V232 HydrophobicContact CG-CB 4.2Å; R112-V232 HydrophobicContact CG-CG1 3.97Å; R112-V232 PolarHBondContact NH1-O 3.22Å; W228-V232 HydrophobicContact CD2-CB 4.21Å; W228-V232 HydrophobicContact CD2-CG2 3.81Å; W228-V232 HydrophobicContact CE3-CB 4.48Å; W228-V232 HydrophobicContact CE3-CG2 3.63Å; W228-V232 HydrophobicContact CG-CG2 4.45Å; W228-V232 HydrophobicContact CH2-CG1 4.06Å; W228-V232 HydrophobicContact CH2-CG2 4.13Å; W228-V232 HydrophobicContact CZ2-CB 4.25Å; W228-V232 HydrophobicContact CZ2-CG1 3.8Å; W228-V232 HydrophobicContact CZ2-CG2 4.27Å; W228-V232 HydrophobicContact CZ3-CG2 3.83Å; W228-V232 WeakPolarHBondContact O-CB 3.46Å; W228-V232 PolarHBondContact O-N 3.08Å
233	A	84.6	Confident	87.4	Confident	13 Å²	13	60.3 Å²	60.3	11%	0.107	31%	0.307	C	S	.	.			trans	-110.6	151.2	171.1	0	0	0	0	0	111.2	W173 S235 K238 D239	W173-A233 HydrophobicContact CZ2-CB 4.2Å; W173-A233 WeakPolarHBondContact CZ2-O 3.47Å; W173-A233 PolarHBondContact NE1-O 3.2Å; W173-A233 VanDerWaalsContact NE1-O 3.08Å; A233-S235 VanDerWaalsContact C-N 3.29Å; A233-S235 PolarHBondContact O-N 3.16Å; A233-K238 HydrophobicContact CB-CB 4.27Å; A233-D239 HydrophobicContact CB-CB 3.92Å
234	D	77.6	Confident	86.7	Confident	30 Å²	30	62.9 Å²	62.9	16%	0.16	32%	0.316	C	S	.	.	S	Bend	trans	-62.5	-36.9	-179	-75.9	-69.9	0	0	0	112.3	R112 Q172 W173	R112-D234 WeakPolarHBondContact CB-OD1 3.48Å; R112-D234 IonicContact CZ-OD2 3.6Å; R112-D234 IonicContact NE-OD1 3.79Å; R112-D234 IonicContact NE-OD2 3.25Å; R112-D234 PolarHBondContact NE-OD2 2.96Å; R112-D234 VanDerWaalsContact NE-OD2 3.13Å; R112-D234 IonicContact NH2-OD2 3.13Å; Q172-D234 PolarHBondContact OE1-O 3.23Å; W173-D234 PolarHBondContact NE1-O 2.95Å
235	S	78.6	Confident	86.2	Confident	14 Å²	14	69.3 Å²	69.3	10%	0.098	35%	0.347	C	S	.	.	S	Bend	trans	-130.7	149.5	176.8	66.7	0	0	0	0	110.3	A233 S237 K238 D239	A233-S235 VanDerWaalsContact C-N 3.29Å; A233-S235 PolarHBondContact O-N 3.16Å; S235-S237 PolarHBondContact O-N 3.4Å; S235-S237 PolarHBondContact OG-OG 2.99Å; S235-K238 PolarHBondContact O-N 3.44Å; S235-K238 WeakPolarHBondContact OG-CG 3.29Å; S235-D239 PolarHBondContact O-N 3.34Å
236	P	79.8	Confident	85.7	Confident	2 Å²	2	69.4 Å²	69.4	1%	0.013	35%	0.347	C	S	.	.	G	3₁₀ helix	trans	-58.5	-32.4	177.2	21.9	-33	0	0	0	112.2	Q172 W173 K238 D239 I242 L247 I250	Q172-P236 WeakPolarHBondContact O-CG 3.23Å; W173-P236 HydrophobicContact CD2-CB 4.25Å; W173-P236 HydrophobicContact CE3-CB 4.11Å; W173-P236 HydrophobicContact CH2-CB 4.26Å; W173-P236 HydrophobicContact CZ2-CB 4.41Å; W173-P236 HydrophobicContact CZ3-CB 4.12Å; P236-K238 PolarHBondContact O-N 2.85Å; P236-D239 PolarHBondContact O-N 2.85Å; P236-D239 VanDerWaalsContact O-N 3.14Å; P236-I242 HydrophobicContact CB-CD1 3.49Å; P236-I242 VanDerWaalsContact CB-CD1 3.49Å; P236-I242 WeakPolarHBondContact O-CG2 3.42Å; P236-L247 HydrophobicContact CB-CD1 4.03Å; P236-L247 HydrophobicContact CG-CD1 4.42Å; P236-I250 HydrophobicContact CB-CD1 4.23Å; P236-I250 HydrophobicContact CG-CG2 4.2Å
237	S	79.3	Confident	85.2	Confident	76 Å²	76	65.2 Å²	65.2	53%	0.531	33%	0.325	S	S	.	.	G	3₁₀ helix	trans	-64.2	-20.6	175.9	53.9	0	0	0	0	115	S235	S235-S237 PolarHBondContact O-N 3.4Å; S235-S237 PolarHBondContact OG-OG 2.99Å
238	K	82.4	Confident	84.6	Confident	154 Å²	154	63.8 Å²	63.8	67%	0.67	33%	0.325	S	S	*	.	G	3₁₀ helix	trans	-97	-6.9	177.6	-70.9	-179.7	-179	-176.3	0	112.3	A233 S235 P236 K240	A233-K238 HydrophobicContact CB-CB 4.27Å; S235-K238 PolarHBondContact O-N 3.44Å; S235-K238 WeakPolarHBondContact OG-CG 3.29Å; P236-K238 PolarHBondContact O-N 2.85Å; K238-K240 PolarHBondContact O-N 3.37Å
239	D	83.5	Confident	84	Confident	18 Å²	18	66.8 Å²	66.8	10%	0.096	34%	0.341	C	S	.	.			trans	-78.4	122.8	178.6	-165	-26.7	0	0	0	110.1	R26 W173 A233 S235 P236 K241 I242	R26-D239 WeakPolarHBondContact CG-OD2 3.4Å; R26-D239 IonicContact CZ-OD2 3.56Å; R26-D239 IonicContact NE-OD1 2.76Å; R26-D239 IonicContact NE-OD2 3.47Å; R26-D239 PolarHBondContact NE-OD2 3.5Å; R26-D239 IonicContact NH2-OD1 2.73Å; R26-D239 IonicContact NH2-OD2 3.54Å; R26-D239 PolarHBondContact NH2-OD2 3.49Å; W173-D239 HydrophobicContact CH2-CB 3.67Å; W173-D239 VanDerWaalsContact CH2-OD2 3.29Å; W173-D239 WeakPolarHBondContact CH2-OD2 3.44Å; W173-D239 HydrophobicContact CZ2-CB 4.19Å; A233-D239 HydrophobicContact CB-CB 3.92Å; S235-D239 PolarHBondContact O-N 3.34Å; P236-D239 PolarHBondContact O-N 2.85Å; P236-D239 VanDerWaalsContact O-N 3.14Å; D239-K241 PolarHBondContact O-N 3.05Å; D239-K241 PolarHBondContact OD1-N 3.49Å; D239-I242 HydrophobicContact CB-CB 4.26Å; D239-I242 HydrophobicContact CB-CG2 4.47Å; D239-I242 WeakPolarHBondContact O-CG2 3.5Å
240	K	81.8	Confident	83.6	Confident	209 Å²	209	65 Å²	65	91%	0.909	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.5	-19.8	178.2	-62.6	-176.9	178.4	-176.4	0	113.1	K238	K238-K240 PolarHBondContact O-N 3.37Å
241	K	86.1	Confident	83	Confident	148 Å²	148	64.9 Å²	64.9	64%	0.643	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104	-0.6	-173.3	-65.7	-177.8	179.1	-177.2	0	113.8	D239	D239-K241 PolarHBondContact O-N 3.05Å; D239-K241 PolarHBondContact OD1-N 3.49Å
242	I	87.1	Confident	82.3	Confident	20 Å²	20	71.5 Å²	71.5	10%	0.103	35%	0.35	C	S	.	.			trans	-74.3	140.7	178.9	-159.3	169.2	0	0	0	110.6	R26 W173 P236 D239 E246 L247 I250	R26-I242 HydrophobicContact CB-CG1 4.29Å; W173-I242 HydrophobicContact CZ3-CD1 4.25Å; P236-I242 HydrophobicContact CB-CD1 3.49Å; P236-I242 VanDerWaalsContact CB-CD1 3.49Å; P236-I242 WeakPolarHBondContact O-CG2 3.42Å; D239-I242 HydrophobicContact CB-CB 4.26Å; D239-I242 HydrophobicContact CB-CG2 4.47Å; D239-I242 WeakPolarHBondContact O-CG2 3.5Å; I242-E246 HydrophobicContact CD1-CG 4.23Å; I242-E246 HydrophobicContact CG1-CB 4.15Å; I242-E246 HydrophobicContact CG1-CG 4.15Å; I242-L247 HydrophobicContact CD1-CB 4.32Å; I242-L247 HydrophobicContact CD1-CD1 4.33Å; I242-I250 HydrophobicContact CD1-CD1 4.17Å
243	T	86.1	Confident	81.1	Confident	59 Å²	59	73.5 Å²	73.5	36%	0.362	36%	0.361	S	S	.	.			trans	-78.8	149.4	173.1	59.3	0	0	0	0	110.2	E245 E246 L247	T243-E245 VanDerWaalsContact C-N 3.27Å; T243-E245 PolarHBondContact O-N 2.82Å; T243-E246 PolarHBondContact O-N 3.37Å; T243-E246 VanDerWaalsContact OG1-CB 3.22Å; T243-E246 WeakPolarHBondContact OG1-CB 3.33Å; T243-E246 PolarHBondContact OG1-N 2.83Å; T243-L247 PolarHBondContact O-N 2.95Å
244	Q	83.1	Confident	80	Confident	145 Å²	145	77.9 Å²	77.9	68%	0.678	37%	0.374	S	S	*	.	H	α-helix	trans	-63.7	-35	178.7	-67.2	-60	-22.5	0	0	112	L247 A248	Q244-L247 PolarHBondContact O-N 2.82Å; Q244-A248 WeakPolarHBondContact O-CB 3.47Å; Q244-A248 PolarHBondContact O-N 3.14Å
245	E	83.9	Confident	78.6	Confident	151 Å²	151	78.4 Å²	78.4	71%	0.706	38%	0.38	S	S	*	.	H	α-helix	trans	-59.4	-45.9	173.4	-64.3	173.9	-168	0	0	112	T243 A248 L249	T243-E245 VanDerWaalsContact C-N 3.27Å; T243-E245 PolarHBondContact O-N 2.82Å; E245-A248 PolarHBondContact O-N 3.34Å; E245-L249 WeakPolarHBondContact O-CB 3.36Å; E245-L249 PolarHBondContact O-N 3.34Å
246	E	83.5	Confident	77	Confident	10 Å²	10	82.6 Å²	82.6	5%	0.047	42%	0.415	C	S	.	.	H	α-helix	trans	-67.6	-39.9	177.5	-176.9	175.2	-167.1	0	0	111.9	R26 R27 I242 T243 A248 L249 I250	R26-E246 VanDerWaalsContact CB-OE2 3.26Å; R26-E246 WeakPolarHBondContact CB-OE2 3.48Å; R26-E246 PolarHBondContact N-OE1 3.43Å; R26-E246 VanDerWaalsContact N-OE1 3.14Å; R26-E246 PolarHBondContact N-OE2 3.06Å; R27-E246 WeakPolarHBondContact CB-OE1 3.41Å; R27-E246 WeakPolarHBondContact CG-OE1 3.5Å; R27-E246 PolarHBondContact N-OE1 3.35Å; I242-E246 HydrophobicContact CD1-CG 4.23Å; I242-E246 HydrophobicContact CG1-CB 4.15Å; I242-E246 HydrophobicContact CG1-CG 4.15Å; T243-E246 PolarHBondContact O-N 3.37Å; T243-E246 VanDerWaalsContact OG1-CB 3.22Å; T243-E246 WeakPolarHBondContact OG1-CB 3.33Å; T243-E246 PolarHBondContact OG1-N 2.83Å; E246-A248 VanDerWaalsContact C-N 3.34Å; E246-A248 PolarHBondContact O-N 3.46Å; E246-L249 PolarHBondContact O-N 2.9Å; E246-I250 HydrophobicContact CG-CD1 4.02Å; E246-I250 WeakPolarHBondContact O-CG1 3.3Å; E246-I250 PolarHBondContact O-N 3.19Å
247	L	83.5	Confident	75.1	Confident	12 Å²	12	87.3 Å²	87.3	6%	0.063	44%	0.437	C	S	.	.	H	α-helix	trans	-63.3	-40.9	176.5	-175.4	65.6	0	0	0	111.6	P236 I242 T243 Q244 I250 R251	P236-L247 HydrophobicContact CB-CD1 4.03Å; P236-L247 HydrophobicContact CG-CD1 4.42Å; I242-L247 HydrophobicContact CD1-CB 4.32Å; I242-L247 HydrophobicContact CD1-CD1 4.33Å; T243-L247 PolarHBondContact O-N 2.95Å; Q244-L247 PolarHBondContact O-N 2.82Å; L247-I250 PolarHBondContact O-N 3.47Å; L247-R251 WeakPolarHBondContact O-CB 3.5Å; L247-R251 VanDerWaalsContact O-CG 3.31Å; L247-R251 WeakPolarHBondContact O-CG 3.11Å; L247-R251 PolarHBondContact O-N 3.32Å
248	A	82.8	Confident	73.4	Confident	54 Å²	54	89.4 Å²	89.4	45%	0.446	43%	0.434	S	S	.	.	H	α-helix	trans	-62.4	-47	174.9	0	0	0	0	0	111.1	Q244 E245 E246 I250 R251 E252	Q244-A248 WeakPolarHBondContact O-CB 3.47Å; Q244-A248 PolarHBondContact O-N 3.14Å; E245-A248 PolarHBondContact O-N 3.34Å; E246-A248 VanDerWaalsContact C-N 3.34Å; E246-A248 PolarHBondContact O-N 3.46Å; A248-I250 VanDerWaalsContact C-N 3.33Å; A248-I250 PolarHBondContact O-N 2.99Å; A248-R251 PolarHBondContact O-N 3.19Å; A248-R251 VanDerWaalsContact O-N 3.12Å; A248-E252 WeakPolarHBondContact O-CB 3.31Å; A248-E252 PolarHBondContact O-N 3.41Å
249	L	81.7	Confident	71.2	Confident	62 Å²	62	89.6 Å²	89.6	33%	0.325	44%	0.442	S	S	.	.	H	α-helix	trans	-59.1	-40.8	177.5	-177.3	147.7	0	0	0	112.6	P175 E245 E246 N253	P175-L249 HydrophobicContact CB-CD2 3.93Å; P175-L249 HydrophobicContact CG-CD2 3.44Å; P175-L249 VanDerWaalsContact CG-CD2 3.44Å; E245-L249 WeakPolarHBondContact O-CB 3.36Å; E245-L249 PolarHBondContact O-N 3.34Å; E246-L249 PolarHBondContact O-N 2.9Å; L249-N253 PolarHBondContact O-N 2.61Å; L249-N253 PolarHBondContact O-ND2 3.24Å
250	I	80.5	Confident	68.9	Low	4 Å²	4	97.9 Å²	97.9	2%	0.021	47%	0.472	C	S	.	.	H	α-helix	trans	-70.3	-35.3	177.8	-67.1	166.6	0	0	0	111.5	Q172 P175 P236 I242 E246 L247 A248	Q172-I250 VanDerWaalsContact O-CG2 3.27Å; Q172-I250 WeakPolarHBondContact O-CG2 3.48Å; P175-I250 HydrophobicContact CG-CG1 4.25Å; P236-I250 HydrophobicContact CB-CD1 4.23Å; P236-I250 HydrophobicContact CG-CG2 4.2Å; I242-I250 HydrophobicContact CD1-CD1 4.17Å; E246-I250 HydrophobicContact CG-CD1 4.02Å; E246-I250 WeakPolarHBondContact O-CG1 3.3Å; E246-I250 PolarHBondContact O-N 3.19Å; L247-I250 PolarHBondContact O-N 3.47Å; A248-I250 VanDerWaalsContact C-N 3.33Å; A248-I250 PolarHBondContact O-N 2.99Å
251	R	78.9	Confident	67	Low	146 Å²	146	95.4 Å²	95.4	55%	0.551	46%	0.457	S	S	*	.	H	α-helix	trans	-72.4	-44.3	179.5	-76.7	177.8	179.3	-176.8	0.6	112.4	L247 A248 N253 R254	L247-R251 WeakPolarHBondContact O-CB 3.5Å; L247-R251 VanDerWaalsContact O-CG 3.31Å; L247-R251 WeakPolarHBondContact O-CG 3.11Å; L247-R251 PolarHBondContact O-N 3.32Å; A248-R251 PolarHBondContact O-N 3.19Å; A248-R251 VanDerWaalsContact O-N 3.12Å; R251-N253 VanDerWaalsContact C-N 3.31Å; R251-N253 PolarHBondContact O-N 2.98Å; R251-R254 WeakPolarHBondContact O-CB 3.44Å; R251-R254 PolarHBondContact O-N 3.11Å; R251-R254 VanDerWaalsContact O-N 3.13Å
252	E	74.4	Confident	64.6	Low	167 Å²	167	97.2 Å²	97.2	78%	0.78	47%	0.465	S	S	*	.	H	α-helix	trans	-63.4	-38.6	-180	-170.7	-175.7	179.2	0	0	111.6	A248 R254	A248-E252 WeakPolarHBondContact O-CB 3.31Å; A248-E252 PolarHBondContact O-N 3.41Å; E252-R254 PolarHBondContact O-N 3.47Å
253	N	64.5	Low	62.5	Low	50 Å²	50	102.7 Å²	102.7	27%	0.267	50%	0.499	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.2	13.5	177.1	-67.6	-72.8	0	0	0	113.5	L249 R251	L249-N253 PolarHBondContact O-N 2.61Å; L249-N253 PolarHBondContact O-ND2 3.24Å; R251-N253 VanDerWaalsContact C-N 3.31Å; R251-N253 PolarHBondContact O-N 2.98Å
254	R	61.3	Low	60.8	Low	104 Å²	104	103.3 Å²	103.3	39%	0.392	50%	0.503	S	S	.	.	S	Bend	trans	-99.1	115.8	174.5	-166.6	-179.6	-68.8	178.6	-3.1	108.1	Q172 R251 E252 A256	Q172-R254 PolarHBondContact O-NH2 3Å; R251-R254 WeakPolarHBondContact O-CB 3.44Å; R251-R254 PolarHBondContact O-N 3.11Å; R251-R254 VanDerWaalsContact O-N 3.13Å; E252-R254 PolarHBondContact O-N 3.47Å; R254-A256 PolarHBondContact O-N 2.68Å; R254-A256 VanDerWaalsContact O-N 3.16Å
255	P	48.7	Very low	59.8	Low	42 Å²	42	100.1 Å²	100.1	27%	0.273	50%	0.497	S	S	.	.			trans	-55.6	126.1	175.5	-22.6	30.9	0	0	0	110	E257 Y258	P255-E257 PolarHBondContact O-N 3.44Å; P255-Y258 PolarHBondContact O-N 3.29Å
256	A	44	Very low	59	Low	101 Å²	101	94.5 Å²	94.5	84%	0.835	47%	0.473	S	S	*	.	G	3₁₀ helix	trans	-55.5	-15.7	175.1	0	0	0	0	0	112.8	R254 Y258	R254-A256 PolarHBondContact O-N 2.68Å; R254-A256 VanDerWaalsContact O-N 3.16Å; A256-Y258 PolarHBondContact O-N 3.42Å
257	E	39.9	Very low	58.6	Low	102 Å²	102	95.3 Å²	95.3	48%	0.477	48%	0.479	S	S	.	.	G	3₁₀ helix	trans	-85.7	8.3	-179.5	-75.5	-163.7	131.7	0	0	116.4	P255 N259 R260 R261	P255-E257 PolarHBondContact O-N 3.44Å; E257-N259 PolarHBondContact O-N 3.18Å; E257-N259 VanDerWaalsContact O-N 3.11Å; E257-R260 HydrophobicContact CB-CB 4.19Å; E257-R260 HydrophobicContact CG-CB 4.13Å; E257-R260 PolarHBondContact O-N 2.97Å; E257-R261 PolarHBondContact O-N 3.08Å
258	Y	44	Very low	58.2	Low	120 Å²	120	101.4 Å²	101.4	47%	0.471	50%	0.501	S	S	.	.	G	3₁₀ helix	trans	-55.7	-30.8	169.8	-166.4	-93.8	0	0	0	111.9	P255 A256	P255-Y258 PolarHBondContact O-N 3.29Å; A256-Y258 PolarHBondContact O-N 3.42Å
259	N	35.6	Very low	58	Low	157 Å²	157	107.2 Å²	107.2	84%	0.84	52%	0.516	S	S	*	.	G	3₁₀ helix	trans	-80.7	-14.3	174.9	-70.6	-18.1	0	0	0	114.3	E257	E257-N259 PolarHBondContact O-N 3.18Å; E257-N259 VanDerWaalsContact O-N 3.11Å
260	R	34.8	Very low	57.7	Low	193 Å²	193	110.8 Å²	110.8	73%	0.728	53%	0.526	S	S	*	.	G	3₁₀ helix	trans	-99.3	11.5	-179.9	-96.2	-170.4	-168.8	-174.8	3.3	114.1	E257 K262	E257-R260 HydrophobicContact CB-CB 4.19Å; E257-R260 HydrophobicContact CG-CB 4.13Å; E257-R260 PolarHBondContact O-N 2.97Å; R260-K262 PolarHBondContact O-N 3.18Å
261	R	42.8	Very low	57.6	Low	157 Å²	157	110.6 Å²	110.6	59%	0.592	53%	0.525	S	S	*	.			trans	-66.4	72.1	165.5	-69.7	-176.3	-172.5	-179.9	1.9	109.7	E257 T263	E257-R261 PolarHBondContact O-N 3.08Å; R261-T263 PolarHBondContact O-N 3.07Å
262	K	35.8	Very low	57.9	Low	186 Å²	186	107.4 Å²	107.4	81%	0.809	52%	0.518	S	S	*	.			trans	-50.7	128.6	158.8	-79.9	-173.2	175.5	-177.2	0	106	R260 T264	R260-K262 PolarHBondContact O-N 3.18Å; K262-T264 PolarHBondContact O-N 3Å
263	T	43.1	Very low	58.5	Low	135 Å²	135	106.3 Å²	106.3	83%	0.828	52%	0.517	S	S	*	.			trans	-63.8	75.4	-179.9	48.1	0	0	0	0	109.5	R261 S265	R261-T263 PolarHBondContact O-N 3.07Å; T263-S265 PolarHBondContact O-N 2.73Å
264	T	50.8	Low	59.5	Low	71 Å²	71	104.3 Å²	104.3	44%	0.436	51%	0.507	S	S	.	.	P	Polyproline II helix	trans	-57.8	125.5	162.6	41.6	0	0	0	0	107.1	K262 K416	K262-T264 PolarHBondContact O-N 3Å; T264-K416 PolarHBondContact O-NZ 3.12Å; T264-K416 PolarHBondContact OG1-NZ 3.45Å; T264-K416 VanDerWaalsContact OG1-NZ 3.13Å
265	S	60.9	Low	60.9	Low	79 Å²	79	104.1 Å²	104.1	55%	0.552	51%	0.513	S	S	*	.	P	Polyproline II helix	trans	-59.3	140.3	178	82.3	0	0	0	0	108.4	T263 P267	T263-S265 PolarHBondContact O-N 2.73Å; S265-P267 WeakPolarHBondContact O-CD 3.31Å
266	V	67.9	Low	62.8	Low	32 Å²	32	102.4 Å²	102.4	19%	0.194	50%	0.501	C	S	.	.	P	Polyproline II helix	trans	-77.5	123.5	177.5	175.6	0	0	0	0	107.2	W268 I271 V420	V266-W268 HydrophobicContact CG1-CD2 4.09Å; V266-W268 HydrophobicContact CG1-CG 4.33Å; V266-W268 HydrophobicContact CG1-CZ2 4.33Å; V266-W268 PolarHBondContact O-N 3.34Å; V266-I271 HydrophobicContact CG1-CD1 3.78Å; V266-V420 HydrophobicContact CG1-CG1 4.28Å; V266-V420 HydrophobicContact CG1-CG2 4.28Å
267	P	74.2	Confident	64.9	Low	28 Å²	28	97.7 Å²	97.7	18%	0.182	46%	0.462	C	S	.	.			trans	-77.7	68.3	-177.6	32.4	-35.5	0	0	0	110.9	S265 K269 R270 I271 Y417 W481	S265-P267 WeakPolarHBondContact O-CD 3.31Å; P267-K269 VanDerWaalsContact C-N 3.33Å; P267-K269 PolarHBondContact O-N 3.15Å; P267-R270 HydrophobicContact CB-CB 4.36Å; P267-R270 HydrophobicContact CB-CG 4.47Å; P267-R270 PolarHBondContact O-N 2.82Å; P267-I271 HydrophobicContact CG-CD1 4.41Å; P267-I271 PolarHBondContact O-N 3.49Å; P267-I271 VanDerWaalsContact O-N 3.09Å; P267-Y417 HydrophobicContact CG-CE1 4.38Å; P267-W481 HydrophobicContact CG-CB 4.41Å
268	W	76.6	Confident	67.4	Low	139 Å²	139	98.2 Å²	98.2	53%	0.527	46%	0.46	S	S	.	.	H	α-helix	trans	-51.2	-47.5	-173.4	-72	103.3	0	0	0	113.3	V266 R270 I271 L272 V420 I424	V266-W268 HydrophobicContact CG1-CD2 4.09Å; V266-W268 HydrophobicContact CG1-CG 4.33Å; V266-W268 HydrophobicContact CG1-CZ2 4.33Å; V266-W268 PolarHBondContact O-N 3.34Å; W268-R270 VanDerWaalsContact C-N 3.32Å; W268-R270 PolarHBondContact O-N 3.44Å; W268-I271 PolarHBondContact O-N 3.29Å; W268-L272 WeakPolarHBondContact O-CB 3.41Å; W268-L272 VanDerWaalsContact O-CG 3.3Å; W268-L272 WeakPolarHBondContact O-CG 3.36Å; W268-L272 PolarHBondContact O-N 3.14Å; W268-V420 HydrophobicContact CE3-CG1 4.47Å; W268-V420 HydrophobicContact CH2-CG1 4.01Å; W268-V420 HydrophobicContact CZ3-CG1 3.83Å; W268-I424 HydrophobicContact CZ3-CD1 4.24Å
269	K	76.7	Confident	69.7	Low	176 Å²	176	92.6 Å²	92.6	77%	0.765	44%	0.439	S	S	*	.	H	α-helix	trans	-57.5	-45	179.4	-69.5	-174.1	178.3	-178.2	0	111.5	P267 L272 L273	P267-K269 VanDerWaalsContact C-N 3.33Å; P267-K269 PolarHBondContact O-N 3.15Å; K269-L272 PolarHBondContact O-N 2.89Å; K269-L273 WeakPolarHBondContact O-CB 3.3Å; K269-L273 WeakPolarHBondContact O-CD1 3.17Å; K269-L273 WeakPolarHBondContact O-CG 3.35Å; K269-L273 PolarHBondContact O-N 3.4Å
270	R	76.6	Confident	72.4	Confident	137 Å²	137	85.1 Å²	85.1	52%	0.517	40%	0.399	S	S	.	.	H	α-helix	trans	-70.4	-35.4	-178.4	-60.1	-174.9	176.7	179.8	-0.7	112.3	P267 W268 S274 W481	P267-R270 HydrophobicContact CB-CB 4.36Å; P267-R270 HydrophobicContact CB-CG 4.47Å; P267-R270 PolarHBondContact O-N 2.82Å; W268-R270 VanDerWaalsContact C-N 3.32Å; W268-R270 PolarHBondContact O-N 3.44Å; R270-S274 WeakPolarHBondContact O-CB 2.95Å; R270-S274 PolarHBondContact O-N 3.1Å; R270-W481 HydrophobicContact CB-CB 3.58Å; R270-W481 HydrophobicContact CB-CG 4.2Å; R270-W481 HydrophobicContact CG-CB 4.4Å
271	I	78.4	Confident	75.1	Confident	0 Å²	0	76 Å²	76	0%	0	37%	0.365	C	S	.	.	H	α-helix	trans	-66.9	-47	175.4	-65.9	170	0	0	0	110.3	V266 P267 W268 L273 S274 V277 Y417 V420 V421 I424 W481	V266-I271 HydrophobicContact CG1-CD1 3.78Å; P267-I271 HydrophobicContact CG-CD1 4.41Å; P267-I271 PolarHBondContact O-N 3.49Å; P267-I271 VanDerWaalsContact O-N 3.09Å; W268-I271 PolarHBondContact O-N 3.29Å; I271-L273 VanDerWaalsContact C-N 3.28Å; I271-L273 PolarHBondContact O-N 2.86Å; I271-S274 VanDerWaalsContact O-CB 3.31Å; I271-S274 WeakPolarHBondContact O-CB 3.32Å; I271-S274 PolarHBondContact O-N 3.12Å; I271-S274 VanDerWaalsContact O-N 3.14Å; I271-V277 HydrophobicContact CG2-CG1 4.38Å; I271-Y417 HydrophobicContact CD1-CD1 4.31Å; I271-V420 HydrophobicContact CD1-CG1 4.2Å; I271-V421 HydrophobicContact CG2-CG2 4.33Å; I271-I424 HydrophobicContact CG2-CD1 3.97Å; I271-W481 HydrophobicContact CD1-CE3 4.49Å; I271-W481 HydrophobicContact CG1-CD2 3.99Å; I271-W481 HydrophobicContact CG1-CE3 3.97Å; I271-W481 HydrophobicContact CG1-CZ3 4.3Å
272	L	84.1	Confident	77.6	Confident	80 Å²	80	70.7 Å²	70.7	42%	0.419	35%	0.349	S	S	.	.	H	α-helix	trans	-70.2	-22.6	-179	-67.7	174.5	0	0	0	113.3	W268 K269 W278 I424	W268-L272 WeakPolarHBondContact O-CB 3.41Å; W268-L272 VanDerWaalsContact O-CG 3.3Å; W268-L272 WeakPolarHBondContact O-CG 3.36Å; W268-L272 PolarHBondContact O-N 3.14Å; K269-L272 PolarHBondContact O-N 2.89Å; L272-W278 PolarHBondContact O-NE1 2.78Å; L272-I424 HydrophobicContact CD2-CD1 4.06Å
273	L	87.1	Confident	80.5	Confident	143 Å²	143	61.8 Å²	61.8	75%	0.749	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.5	-3.5	173.4	-68.4	168.8	0	0	0	113.1	K269 I271 I275	K269-L273 WeakPolarHBondContact O-CB 3.3Å; K269-L273 WeakPolarHBondContact O-CD1 3.17Å; K269-L273 WeakPolarHBondContact O-CG 3.35Å; K269-L273 PolarHBondContact O-N 3.4Å; I271-L273 VanDerWaalsContact C-N 3.28Å; I271-L273 PolarHBondContact O-N 2.86Å; L273-I275 PolarHBondContact O-N 2.8Å
274	S	85.5	Confident	82.9	Confident	8 Å²	8	55.4 Å²	55.4	6%	0.056	27%	0.271	C	S	.	.			trans	-80.3	114	-175.5	-173.7	0	0	0	0	111.5	R270 I271 V277 W278 W481	R270-S274 WeakPolarHBondContact O-CB 2.95Å; R270-S274 PolarHBondContact O-N 3.1Å; I271-S274 VanDerWaalsContact O-CB 3.31Å; I271-S274 WeakPolarHBondContact O-CB 3.32Å; I271-S274 PolarHBondContact O-N 3.12Å; I271-S274 VanDerWaalsContact O-N 3.14Å; S274-V277 WeakPolarHBondContact O-CB 3.4Å; S274-V277 PolarHBondContact O-N 2.98Å; S274-V277 VanDerWaalsContact O-N 3.16Å; S274-W278 PolarHBondContact O-N 3.17Å; S274-W481 PolarHBondContact OG-NE1 2.93Å
275	I	90.8	Very high	85	Confident	101 Å²	101	54 Å²	54	52%	0.518	26%	0.259	S	S	.	.	H	α-helix	trans	-57.8	-43.8	178.6	-62.4	173.9	0	0	0	112.5	L273 V277 W278 A279 F473	L273-I275 PolarHBondContact O-N 2.8Å; I275-V277 VanDerWaalsContact C-N 3.27Å; I275-V277 PolarHBondContact O-N 3.08Å; I275-W278 PolarHBondContact O-N 2.98Å; I275-W278 VanDerWaalsContact O-N 3.15Å; I275-A279 PolarHBondContact O-N 3.09Å; I275-F473 HydrophobicContact CG2-CB 3.72Å; I275-F473 HydrophobicContact CG2-CD1 3.51Å; I275-F473 HydrophobicContact CG2-CE1 4.35Å; I275-F473 HydrophobicContact CG2-CG 3.78Å
276	P	89.5	Confident	86.7	Confident	5 Å²	5	50.3 Å²	50.3	3%	0.032	23%	0.233	C	C	.	.	H	α-helix	trans	-63	-30.7	176.9	-28.1	39.2	0	0	0	114.2	A279 I280 Q475	P276-A279 WeakPolarHBondContact O-CB 3.21Å; P276-A279 PolarHBondContact O-N 3.43Å; P276-I280 WeakPolarHBondContact O-CG1 3.36Å; P276-I280 PolarHBondContact O-N 3.12Å; P276-Q475 HydrophobicContact CB-CB 4.05Å; P276-Q475 HydrophobicContact CB-CG 4.44Å; P276-Q475 HydrophobicContact CG-CB 3.88Å; P276-Q475 HydrophobicContact CG-CG 3.82Å
277	V	87.4	Confident	88.1	Confident	3 Å²	3	48.8 Å²	48.8	2%	0.018	22%	0.224	C	C	.	.	H	α-helix	trans	-64.8	-47.8	173.6	172.3	0	0	0	0	109.5	I271 S274 I275 A279 I280 V281 V402 V421 W481	I271-V277 HydrophobicContact CG2-CG1 4.38Å; S274-V277 WeakPolarHBondContact O-CB 3.4Å; S274-V277 PolarHBondContact O-N 2.98Å; S274-V277 VanDerWaalsContact O-N 3.16Å; I275-V277 VanDerWaalsContact C-N 3.27Å; I275-V277 PolarHBondContact O-N 3.08Å; V277-A279 VanDerWaalsContact C-N 3.31Å; V277-A279 PolarHBondContact O-N 3.16Å; V277-I280 PolarHBondContact O-N 2.98Å; V277-V281 HydrophobicContact CG1-CG2 4.36Å; V277-V281 VanDerWaalsContact O-CG2 3.3Å; V277-V281 WeakPolarHBondContact O-CG2 3.33Å; V277-V281 PolarHBondContact O-N 3.02Å; V277-V402 HydrophobicContact CG2-CG1 4.39Å; V277-V421 HydrophobicContact CG1-CG1 4.18Å; V277-V421 HydrophobicContact CG1-CG2 4.3Å; V277-V421 HydrophobicContact CG2-CG2 4.09Å; V277-W481 HydrophobicContact CG2-CZ2 3.93Å
278	W	92.1	Very high	89	Confident	112 Å²	112	47.5 Å²	47.5	42%	0.424	22%	0.216	S	C	.	.	H	α-helix	trans	-63.4	-34.1	176.4	-78.3	105.9	0	0	0	113.4	L272 S274 I275 I280 V281 V282 I428	L272-W278 PolarHBondContact O-NE1 2.78Å; S274-W278 PolarHBondContact O-N 3.17Å; I275-W278 PolarHBondContact O-N 2.98Å; I275-W278 VanDerWaalsContact O-N 3.15Å; W278-I280 VanDerWaalsContact C-N 3.34Å; W278-I280 PolarHBondContact O-N 2.97Å; W278-V281 HydrophobicContact CE3-CB 4.2Å; W278-V281 HydrophobicContact CE3-CG1 4Å; W278-V281 HydrophobicContact CZ3-CG1 4.04Å; W278-V281 PolarHBondContact O-N 3.39Å; W278-V282 WeakPolarHBondContact O-CB 3.42Å; W278-V282 VanDerWaalsContact O-CG2 3.28Å; W278-V282 WeakPolarHBondContact O-CG2 3.3Å; W278-V282 PolarHBondContact O-N 3.31Å; W278-I428 HydrophobicContact CH2-CD1 3.93Å; W278-I428 HydrophobicContact CZ3-CD1 3.8Å
279	A	94	Very high	89.9	Confident	3 Å²	3	41.7 Å²	41.7	3%	0.025	19%	0.194	C	C	.	.	H	α-helix	trans	-57.6	-47.8	172.5	0	0	0	0	0	111.3	I275 P276 V277 V282 A283 Y470 F473 A474	I275-A279 PolarHBondContact O-N 3.09Å; P276-A279 WeakPolarHBondContact O-CB 3.21Å; P276-A279 PolarHBondContact O-N 3.43Å; V277-A279 VanDerWaalsContact C-N 3.31Å; V277-A279 PolarHBondContact O-N 3.16Å; A279-V282 PolarHBondContact O-N 3.16Å; A279-A283 PolarHBondContact O-N 3.24Å; A279-Y470 HydrophobicContact CB-CD2 4.39Å; A279-Y470 WeakPolarHBondContact O-CD2 3.45Å; A279-F473 HydrophobicContact CB-CB 3.85Å; A279-A474 HydrophobicContact CB-CB 4.31Å
280	I	91	Very high	90.8	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-62.9	-44.7	176.6	-64.8	165.7	0	0	0	111.1	P276 V277 W278 V282 A283 H284 N398 Q399 V402 Y470	P276-I280 WeakPolarHBondContact O-CG1 3.36Å; P276-I280 PolarHBondContact O-N 3.12Å; V277-I280 PolarHBondContact O-N 2.98Å; W278-I280 VanDerWaalsContact C-N 3.34Å; W278-I280 PolarHBondContact O-N 2.97Å; I280-V282 VanDerWaalsContact C-N 3.34Å; I280-V282 PolarHBondContact O-N 3.17Å; I280-A283 PolarHBondContact O-N 3.44Å; I280-H284 WeakPolarHBondContact O-CB 3.41Å; I280-H284 PolarHBondContact O-N 3.31Å; I280-N398 HydrophobicContact CD1-CB 4.3Å; I280-N398 HydrophobicContact CG1-CB 4.43Å; I280-Q399 HydrophobicContact CD1-CB 4.37Å; I280-Q399 HydrophobicContact CG2-CB 4.35Å; I280-V402 HydrophobicContact CD1-CB 4.36Å; I280-V402 HydrophobicContact CD1-CG2 3.88Å; I280-Y470 HydrophobicContact CG1-CE2 4.06Å
281	V	92.1	Very high	91.5	Very high	2 Å²	2	27.4 Å²	27.4	1%	0.012	14%	0.136	C	C	.	.	H	α-helix	trans	-58.5	-46.3	177.9	172.5	0	0	0	0	111.1	V277 W278 H284 F285 I424 I428	V277-V281 HydrophobicContact CG1-CG2 4.36Å; V277-V281 VanDerWaalsContact O-CG2 3.3Å; V277-V281 WeakPolarHBondContact O-CG2 3.33Å; V277-V281 PolarHBondContact O-N 3.02Å; W278-V281 HydrophobicContact CE3-CB 4.2Å; W278-V281 HydrophobicContact CE3-CG1 4Å; W278-V281 HydrophobicContact CZ3-CG1 4.04Å; W278-V281 PolarHBondContact O-N 3.39Å; V281-H284 PolarHBondContact O-N 3.32Å; V281-F285 WeakPolarHBondContact O-CB 3.47Å; V281-F285 PolarHBondContact O-N 3.19Å; V281-I424 HydrophobicContact CG2-CG2 4.37Å; V281-I428 HydrophobicContact CG1-CB 3.96Å; V281-I428 HydrophobicContact CG1-CD1 3.6Å; V281-I428 HydrophobicContact CG1-CG1 4.38Å; V281-I428 HydrophobicContact CG1-CG2 3.78Å
282	V	95.4	Very high	92.2	Very high	44 Å²	44	27.7 Å²	27.7	27%	0.267	14%	0.137	S	C	.	.	H	α-helix	trans	-65.6	-42.7	-180	165.9	0	0	0	0	111.6	W278 A279 I280 H284 F285 A286 L469	W278-V282 WeakPolarHBondContact O-CB 3.42Å; W278-V282 VanDerWaalsContact O-CG2 3.28Å; W278-V282 WeakPolarHBondContact O-CG2 3.3Å; W278-V282 PolarHBondContact O-N 3.31Å; A279-V282 PolarHBondContact O-N 3.16Å; I280-V282 VanDerWaalsContact C-N 3.34Å; I280-V282 PolarHBondContact O-N 3.17Å; V282-H284 VanDerWaalsContact C-N 3.34Å; V282-H284 PolarHBondContact O-N 2.94Å; V282-F285 PolarHBondContact O-N 3.31Å; V282-A286 WeakPolarHBondContact O-CB 3.46Å; V282-A286 PolarHBondContact O-N 3.46Å; V282-L469 HydrophobicContact CG1-CB 4Å; V282-L469 HydrophobicContact CG1-CD1 3.74Å
283	A	95.4	Very high	92.6	Very high	0 Å²	0	24 Å²	24	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-62.7	-41.9	175.4	0	0	0	0	0	112.1	A279 I280 A286 E287 T354 L358 F395 Y470	A279-A283 PolarHBondContact O-N 3.24Å; I280-A283 PolarHBondContact O-N 3.44Å; A283-A286 PolarHBondContact O-N 3.25Å; A283-E287 WeakPolarHBondContact O-CB 3.41Å; A283-E287 PolarHBondContact O-N 3.23Å; A283-T354 HydrophobicContact CB-CG2 3.82Å; A283-L358 HydrophobicContact CB-CD1 4.21Å; A283-F395 HydrophobicContact CB-CB 4.38Å; A283-Y470 HydrophobicContact CB-CD2 3.44Å; A283-Y470 VanDerWaalsContact CB-CD2 3.44Å; A283-Y470 HydrophobicContact CB-CE2 4.07Å; A283-Y470 HydrophobicContact CB-CG 4Å
284	H	93.6	Very high	92.8	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.005	9%	0.085	C	C	.	.	H	α-helix	trans	-66.2	-38.6	176.8	-168.7	-171.5	0	0	0	111.7	I280 V281 V282 N288 F395 S425 A429	I280-H284 WeakPolarHBondContact O-CB 3.41Å; I280-H284 PolarHBondContact O-N 3.31Å; V281-H284 PolarHBondContact O-N 3.32Å; V282-H284 VanDerWaalsContact C-N 3.34Å; V282-H284 PolarHBondContact O-N 2.94Å; H284-N288 PolarHBondContact CD2-ND2 3.05Å; H284-N288 PolarHBondContact NE2-ND2 3.05Å; H284-N288 WeakPolarHBondContact O-CB 3.3Å; H284-N288 PolarHBondContact O-N 3.4Å; H284-F395 HydrophobicContact CB-CD2 4.07Å; H284-F395 HydrophobicContact CB-CE2 3.79Å; H284-F395 HydrophobicContact CB-CZ 4.13Å; H284-F395 AromaticContact CD2-CE2 3.46Å; H284-F395 VanDerWaalsContact CD2-CE2 3.46Å; H284-F395 WeakPolarHBondContact CD2-CE2 3.41Å; H284-F395 AromaticContact CD2-CZ 3.46Å; H284-F395 VanDerWaalsContact CD2-CZ 3.46Å; H284-F395 WeakPolarHBondContact CD2-CZ 3.15Å; H284-F395 AromaticContact CG-CE2 3.55Å; H284-F395 AromaticContact CG-CZ 3.92Å; H284-S425 WeakPolarHBondContact CB-OG 3.3Å; H284-S425 PolarHBondContact ND1-OG 2.69Å; H284-A429 HydrophobicContact CB-CB 4.11Å
285	F	96	Very high	93	Very high	41 Å²	41	17.6 Å²	17.6	18%	0.18	8%	0.084	C	C	.	.	H	α-helix	trans	-62.3	-46.7	173.8	-175.7	-87.7	0	0	0	111.9	V281 V282 N288 W289 I428 L431 P432 M462	V281-F285 WeakPolarHBondContact O-CB 3.47Å; V281-F285 PolarHBondContact O-N 3.19Å; V282-F285 PolarHBondContact O-N 3.31Å; F285-N288 PolarHBondContact O-N 3.08Å; F285-W289 HydrophobicContact CE1-CE3 4.28Å; F285-W289 HydrophobicContact CZ-CE3 4.45Å; F285-W289 WeakPolarHBondContact O-CB 3.46Å; F285-W289 PolarHBondContact O-N 3.39Å; F285-I428 HydrophobicContact CD2-CG2 3.82Å; F285-I428 WeakPolarHBondContact CD2-O 3.42Å; F285-I428 HydrophobicContact CE2-CG2 4.48Å; F285-L431 HydrophobicContact CE2-CB 4.1Å; F285-P432 HydrophobicContact CD1-CG 4.3Å; F285-P432 HydrophobicContact CD2-CG 3.69Å; F285-P432 HydrophobicContact CE1-CG 4.12Å; F285-P432 HydrophobicContact CE2-CG 3.53Å; F285-P432 HydrophobicContact CG-CG 4.1Å; F285-P432 HydrophobicContact CZ-CG 3.76Å; F285-M462 HydrophobicContact CD1-CE 3.56Å; F285-M462 HydrophobicContact CE1-CE 3.33Å
286	A	97.1	Very high	92.9	Very high	1 Å²	1	13.3 Å²	13.3	1%	0.008	6%	0.062	C	C	.	.	H	α-helix	trans	-63.3	-42.2	179	0	0	0	0	0	112.1	V282 A283 W289 G290 L358 M462 F463	V282-A286 WeakPolarHBondContact O-CB 3.46Å; V282-A286 PolarHBondContact O-N 3.46Å; A283-A286 PolarHBondContact O-N 3.25Å; A286-W289 WeakPolarHBondContact O-CB 3.29Å; A286-W289 PolarHBondContact O-N 3Å; A286-G290 PolarHBondContact O-N 2.78Å; A286-L358 HydrophobicContact CB-CD2 4.45Å; A286-M462 WeakPolarHBondContact CB-O 3.31Å; A286-F463 WeakPolarHBondContact O-CD1 3.38Å; A286-F463 VanDerWaalsContact O-CE1 3.23Å; A286-F463 WeakPolarHBondContact O-CE1 3.35Å
287	E	96	Very high	92.9	Very high	1 Å²	1	13.9 Å²	13.9	1%	0.005	6%	0.064	C	C	.	.	H	α-helix	trans	-64.3	-49.7	176.5	-164.3	-79.3	163.3	0	0	111.2	A283 W289 G290 F291 M324 L358 A391 W392 F395	A283-E287 WeakPolarHBondContact O-CB 3.41Å; A283-E287 PolarHBondContact O-N 3.23Å; E287-W289 VanDerWaalsContact C-N 3.26Å; E287-W289 PolarHBondContact O-N 3.27Å; E287-G290 PolarHBondContact O-N 3.38Å; E287-F291 WeakPolarHBondContact O-CB 3.39Å; E287-F291 PolarHBondContact O-N 3.43Å; E287-M324 WeakPolarHBondContact OE1-CE 3.43Å; E287-L358 HydrophobicContact CB-CD2 4.16Å; E287-A391 HydrophobicContact CG-CB 4.47Å; E287-W392 WeakPolarHBondContact OE2-CZ3 3.27Å; E287-F395 HydrophobicContact CB-CE1 3.91Å; E287-F395 HydrophobicContact CB-CZ 4.46Å; E287-F395 HydrophobicContact CG-CE1 4.06Å
288	N	93.8	Very high	93.1	Very high	1 Å²	1	13.8 Å²	13.8	1%	0.005	6%	0.063	C	C	.	.	H	α-helix	trans	-65.8	-28.1	178.4	-89.4	-43.6	0	0	0	113.1	H284 F285 Y292 A429	H284-N288 PolarHBondContact CD2-ND2 3.05Å; H284-N288 PolarHBondContact NE2-ND2 3.05Å; H284-N288 WeakPolarHBondContact O-CB 3.3Å; H284-N288 PolarHBondContact O-N 3.4Å; F285-N288 PolarHBondContact O-N 3.08Å; N288-Y292 HydrophobicContact CB-CD2 4Å; N288-Y292 HydrophobicContact CB-CE2 3.77Å; N288-Y292 WeakPolarHBondContact O-CB 3.41Å; N288-Y292 WeakPolarHBondContact O-CD2 3.4Å; N288-Y292 PolarHBondContact O-N 3.48Å; N288-A429 HydrophobicContact CB-CB 4.22Å; N288-A429 WeakPolarHBondContact CB-O 3.37Å; N288-A429 WeakPolarHBondContact ND2-CB 3.32Å; N288-A429 PolarHBondContact ND2-O 2.82Å
289	W	96.2	Very high	93.1	Very high	16 Å²	16	8.5 Å²	8.5	6%	0.061	4%	0.043	C	C	.	.	H	α-helix	trans	-57.7	-55.7	171.5	178.5	-79.7	0	0	0	110.9	F285 A286 E287 T293 P432 I435 L439 I458 T459 M462	F285-W289 HydrophobicContact CE1-CE3 4.28Å; F285-W289 HydrophobicContact CZ-CE3 4.45Å; F285-W289 WeakPolarHBondContact O-CB 3.46Å; F285-W289 PolarHBondContact O-N 3.39Å; A286-W289 WeakPolarHBondContact O-CB 3.29Å; A286-W289 PolarHBondContact O-N 3Å; E287-W289 VanDerWaalsContact C-N 3.26Å; E287-W289 PolarHBondContact O-N 3.27Å; W289-T293 VanDerWaalsContact O-CB 3.26Å; W289-T293 WeakPolarHBondContact O-CB 3.32Å; W289-T293 PolarHBondContact O-N 2.92Å; W289-T293 PolarHBondContact O-OG1 3.14Å; W289-P432 VanDerWaalsContact CA-CB 3.48Å; W289-P432 HydrophobicContact CB-CB 3.94Å; W289-P432 HydrophobicContact CB-CG 4.19Å; W289-P432 HydrophobicContact CD2-CB 4.34Å; W289-P432 HydrophobicContact CE3-CB 3.76Å; W289-P432 HydrophobicContact CE3-CG 4.25Å; W289-P432 HydrophobicContact CG-CB 4.48Å; W289-I435 HydrophobicContact CH2-CG2 4.12Å; W289-I435 HydrophobicContact CZ3-CB 4.28Å; W289-I435 HydrophobicContact CZ3-CG2 3.95Å; W289-L439 HydrophobicContact CH2-CD2 3.74Å; W289-L439 HydrophobicContact CZ2-CD2 3.85Å; W289-I458 HydrophobicContact CZ2-CG2 3.66Å; W289-T459 PolarHBondContact NE1-OG1 2.99Å; W289-M462 HydrophobicContact CD2-CG 3.91Å; W289-M462 HydrophobicContact CG-CB 4.08Å; W289-M462 HydrophobicContact CG-CG 3.9Å
290	G	94.2	Very high	92.9	Very high	3 Å²	3	9 Å²	9	3%	0.031	5%	0.047	C	C	.	.	H	α-helix	trans	-64.3	-44.6	178.2	0	0	0	0	0	112.5	A286 E287 T293 M294	A286-G290 PolarHBondContact O-N 2.78Å; E287-G290 PolarHBondContact O-N 3.38Å; G290-T293 PolarHBondContact O-N 3.31Å; G290-M294 WeakPolarHBondContact O-CB 2.99Å; G290-M294 VanDerWaalsContact O-CG 3.24Å; G290-M294 WeakPolarHBondContact O-CG 3.29Å; G290-M294 PolarHBondContact O-N 3.06Å
291	F	92.6	Very high	92.9	Very high	11 Å²	11	9.2 Å²	9.2	5%	0.048	5%	0.048	C	C	.	.	H	α-helix	trans	-58	-52.7	179.7	178.5	-105.9	0	0	0	111.9	E287 M294 L295 Y321 M324	E287-F291 WeakPolarHBondContact O-CB 3.39Å; E287-F291 PolarHBondContact O-N 3.43Å; F291-M294 PolarHBondContact O-N 2.86Å; F291-L295 HydrophobicContact CE1-CD2 3.89Å; F291-L295 HydrophobicContact CZ-CD1 4.37Å; F291-L295 HydrophobicContact CZ-CD2 4.06Å; F291-L295 WeakPolarHBondContact O-CB 3.08Å; F291-L295 PolarHBondContact O-N 3.27Å; F291-Y321 HydrophobicContact CD2-CE1 4.46Å; F291-Y321 HydrophobicContact CE2-CD1 4.03Å; F291-Y321 HydrophobicContact CE2-CE1 4.15Å; F291-M324 HydrophobicContact CD2-CE 3.94Å; F291-M324 HydrophobicContact CD2-SD 3.75Å; F291-M324 HydrophobicContact CE2-CE 4.27Å; F291-M324 HydrophobicContact CE2-SD 3.78Å
292	Y	91.8	Very high	92.8	Very high	6 Å²	6	9.1 Å²	9.1	2%	0.024	5%	0.047	C	C	.	.	H	α-helix	trans	-68.9	-40.8	-178.8	-66.7	-41.7	0	0	0	112.8	F92 N288 M294 L295 T296 A429 P432	F92-Y292 AromaticContact CE1-CD1 3.81Å; F92-Y292 HydrophobicContact CE1-CD1 3.81Å; F92-Y292 HydrophobicContact CE1-CD2 4.37Å; F92-Y292 AromaticContact CE1-CE1 3.42Å; F92-Y292 HydrophobicContact CE1-CE1 3.42Å; F92-Y292 VanDerWaalsContact CE1-CE1 3.42Å; F92-Y292 HydrophobicContact CE1-CE2 4.03Å; F92-Y292 HydrophobicContact CE1-CG 4.28Å; F92-Y292 AromaticContact CE1-CZ 3.55Å; F92-Y292 HydrophobicContact CE2-CD1 4.44Å; F92-Y292 AromaticContact CZ-CD1 3.45Å; F92-Y292 HydrophobicContact CZ-CD1 3.45Å; F92-Y292 VanDerWaalsContact CZ-CD1 3.45Å; F92-Y292 HydrophobicContact CZ-CD2 4.46Å; F92-Y292 AromaticContact CZ-CE1 3.54Å; F92-Y292 HydrophobicContact CZ-CE1 3.54Å; F92-Y292 AromaticContact CZ-CG 3.96Å; F92-Y292 HydrophobicContact CZ-CG 3.96Å; N288-Y292 HydrophobicContact CB-CD2 4Å; N288-Y292 HydrophobicContact CB-CE2 3.77Å; N288-Y292 WeakPolarHBondContact O-CB 3.41Å; N288-Y292 WeakPolarHBondContact O-CD2 3.4Å; N288-Y292 PolarHBondContact O-N 3.48Å; Y292-M294 VanDerWaalsContact C-N 3.32Å; Y292-M294 PolarHBondContact O-N 3.32Å; Y292-L295 HydrophobicContact CD1-CD2 4.4Å; Y292-L295 PolarHBondContact O-N 3.39Å; Y292-T296 PolarHBondContact O-N 3.49Å; Y292-T296 PolarHBondContact O-OG1 3.28Å; Y292-A429 WeakPolarHBondContact CE2-O 3.48Å; Y292-P432 HydrophobicContact CD2-CB 4.36Å
293	T	93.1	Very high	92.5	Very high	3 Å²	3	8.4 Å²	8.4	2%	0.018	4%	0.042	C	C	.	.	H	α-helix	trans	-54.3	-52.6	176	-55.9	0	0	0	0	109.9	W289 G290 T296 Y297 S436 V440 I455	W289-T293 VanDerWaalsContact O-CB 3.26Å; W289-T293 WeakPolarHBondContact O-CB 3.32Å; W289-T293 PolarHBondContact O-N 2.92Å; W289-T293 PolarHBondContact O-OG1 3.14Å; G290-T293 PolarHBondContact O-N 3.31Å; T293-T296 PolarHBondContact O-N 2.94Å; T293-T296 PolarHBondContact O-OG1 3.37Å; T293-Y297 WeakPolarHBondContact O-CB 3.18Å; T293-Y297 PolarHBondContact O-N 3.26Å; T293-Y297 VanDerWaalsContact O-N 3.1Å; T293-S436 WeakPolarHBondContact CB-OG 3.45Å; T293-S436 WeakPolarHBondContact CG2-OG 3.36Å; T293-S436 WeakPolarHBondContact OG1-CB 3.32Å; T293-S436 PolarHBondContact OG1-OG 2.88Å; T293-V440 HydrophobicContact CG2-CG2 4.27Å; T293-I455 HydrophobicContact CG2-CG2 3.96Å
294	M	91.7	Very high	92.1	Very high	10 Å²	10	9.7 Å²	9.7	5%	0.049	5%	0.049	C	C	.	.	H	α-helix	trans	-64.4	-46.1	178	-62.4	-65.6	168.6	0	0	110.5	G290 F291 Y292 T296 Y297 L298 Y321 V365 V385 F456	G290-M294 WeakPolarHBondContact O-CB 2.99Å; G290-M294 VanDerWaalsContact O-CG 3.24Å; G290-M294 WeakPolarHBondContact O-CG 3.29Å; G290-M294 PolarHBondContact O-N 3.06Å; F291-M294 PolarHBondContact O-N 2.86Å; Y292-M294 VanDerWaalsContact C-N 3.32Å; Y292-M294 PolarHBondContact O-N 3.32Å; M294-T296 VanDerWaalsContact C-N 3.25Å; M294-T296 PolarHBondContact O-N 2.96Å; M294-Y297 PolarHBondContact O-N 2.92Å; M294-L298 HydrophobicContact CB-CB 4.36Å; M294-L298 WeakPolarHBondContact O-CA 3.45Å; M294-L298 WeakPolarHBondContact O-CB 3.28Å; M294-L298 PolarHBondContact O-N 3.08Å; M294-L298 HydrophobicContact SD-CD1 4.42Å; M294-Y321 PolarHBondContact O-OH 3.06Å; M294-V365 HydrophobicContact CE-CG2 4.11Å; M294-V385 HydrophobicContact CB-CG2 4.21Å; M294-V385 HydrophobicContact CG-CG2 3.97Å; M294-F456 HydrophobicContact CE-CD1 3.94Å; M294-F456 HydrophobicContact CE-CE1 3.65Å; M294-F456 HydrophobicContact SD-CE1 4.38Å
295	L	88.3	Confident	91.8	Very high	6 Å²	6	10.6 Å²	10.6	3%	0.031	5%	0.054	C	C	.	.	H	α-helix	trans	-56.2	-38.9	-177.6	-167.5	69.3	0	0	0	113.5	V46 S49 T194 F291 Y292 Y321	V46-L295 HydrophobicContact CG1-CD1 3.74Å; V46-L295 HydrophobicContact CG1-CD2 4.05Å; V46-L295 HydrophobicContact CG1-CG 4.04Å; S49-L295 WeakPolarHBondContact CB-O 3.43Å; S49-L295 PolarHBondContact OG-O 3Å; T194-L295 HydrophobicContact CG2-CD1 3.88Å; F291-L295 HydrophobicContact CE1-CD2 3.89Å; F291-L295 HydrophobicContact CZ-CD1 4.37Å; F291-L295 HydrophobicContact CZ-CD2 4.06Å; F291-L295 WeakPolarHBondContact O-CB 3.08Å; F291-L295 PolarHBondContact O-N 3.27Å; Y292-L295 HydrophobicContact CD1-CD2 4.4Å; Y292-L295 PolarHBondContact O-N 3.39Å; L295-Y321 WeakPolarHBondContact CA-OH 3.16Å; L295-Y321 HydrophobicContact CD1-CD1 4.36Å; L295-Y321 HydrophobicContact CD1-CE1 3.86Å; L295-Y321 HydrophobicContact CD1-CE2 4.32Å; L295-Y321 PolarHBondContact N-OH 3.4Å
296	T	88.8	Confident	91.4	Very high	10 Å²	10	9 Å²	9	6%	0.061	5%	0.048	C	C	.	.	H	α-helix	trans	-83.9	-32.2	-178	50.1	0	0	0	0	113.7	S49 L88 Y292 T293 M294 P437	S49-T296 WeakPolarHBondContact CB-O 3.39Å; L88-T296 HydrophobicContact CB-CG2 4.47Å; Y292-T296 PolarHBondContact O-N 3.49Å; Y292-T296 PolarHBondContact O-OG1 3.28Å; T293-T296 PolarHBondContact O-N 2.94Å; T293-T296 PolarHBondContact O-OG1 3.37Å; M294-T296 VanDerWaalsContact C-N 3.25Å; M294-T296 PolarHBondContact O-N 2.96Å; T296-P437 HydrophobicContact CG2-CG 4.09Å
297	Y	91	Very high	90.8	Very high	18 Å²	18	16.3 Å²	16.3	7%	0.071	8%	0.082	C	C	.	.	H	α-helix	trans	-127.4	-7	-162.8	-91.4	-72.7	0	0	0	114.2	G85 L88 T293 M294 A300 Y301 P437 V440 W452	G85-Y297 WeakPolarHBondContact CA-OH 3.41Å; G85-Y297 PolarHBondContact N-OH 3.23Å; L88-Y297 HydrophobicContact CD1-CD2 4.39Å; L88-Y297 HydrophobicContact CD1-CE1 4.18Å; L88-Y297 HydrophobicContact CD1-CE2 3.8Å; T293-Y297 WeakPolarHBondContact O-CB 3.18Å; T293-Y297 PolarHBondContact O-N 3.26Å; T293-Y297 VanDerWaalsContact O-N 3.1Å; M294-Y297 PolarHBondContact O-N 2.92Å; Y297-A300 HydrophobicContact CD1-CB 4.06Å; Y297-A300 WeakPolarHBondContact O-CB 3.33Å; Y297-A300 PolarHBondContact O-N 2.85Å; Y297-A300 VanDerWaalsContact O-N 3.13Å; Y297-Y301 PolarHBondContact O-N 2.87Å; Y297-P437 HydrophobicContact CE2-CB 3.9Å; Y297-P437 PolarHBondContact OH-O 3.43Å; Y297-V440 HydrophobicContact CD1-CB 4.44Å; Y297-V440 HydrophobicContact CD1-CG1 3.53Å; Y297-V440 HydrophobicContact CD2-CB 3.83Å; Y297-V440 HydrophobicContact CD2-CG1 3.79Å; Y297-V440 HydrophobicContact CD2-CG2 4.06Å; Y297-V440 HydrophobicContact CE1-CB 4.3Å; Y297-V440 HydrophobicContact CE1-CG1 3.55Å; Y297-V440 HydrophobicContact CE2-CB 3.72Å; Y297-V440 HydrophobicContact CE2-CG1 3.86Å; Y297-V440 HydrophobicContact CE2-CG2 4.38Å; Y297-V440 HydrophobicContact CG-CB 4.21Å; Y297-V440 HydrophobicContact CG-CG1 3.64Å; Y297-V440 HydrophobicContact CG-CG2 4.46Å; Y297-W452 HydrophobicContact CD1-CH2 4Å; Y297-W452 HydrophobicContact CG-CH2 4.27Å; Y297-W452 WeakPolarHBondContact O-CH2 3.45Å
298	L	91.5	Very high	90.3	Very high	1 Å²	1	18.4 Å²	18.4	1%	0.005	9%	0.091	C	C	.	.	H	α-helix	trans	-58.3	-45	176.2	177.3	65	0	0	0	112.5	M294 A300 Y301 M302 P320 Y321 V381	M294-L298 HydrophobicContact CB-CB 4.36Å; M294-L298 WeakPolarHBondContact O-CA 3.45Å; M294-L298 WeakPolarHBondContact O-CB 3.28Å; M294-L298 PolarHBondContact O-N 3.08Å; M294-L298 HydrophobicContact SD-CD1 4.42Å; L298-A300 VanDerWaalsContact C-N 3.28Å; L298-A300 PolarHBondContact O-N 3.3Å; L298-Y301 HydrophobicContact CD1-CD1 4.35Å; L298-Y301 PolarHBondContact O-N 3.4Å; L298-M302 HydrophobicContact CD1-CE 3.59Å; L298-M302 HydrophobicContact CD1-CG 4.06Å; L298-M302 HydrophobicContact CG-CE 4.42Å; L298-M302 HydrophobicContact CG-CG 4.29Å; L298-M302 WeakPolarHBondContact O-CB 3.41Å; L298-M302 WeakPolarHBondContact O-CG 3.24Å; L298-M302 PolarHBondContact O-N 3.21Å; L298-P320 HydrophobicContact CD2-CB 4.45Å; L298-P320 HydrophobicContact CD2-CG 3.95Å; L298-Y321 HydrophobicContact CD2-CE2 4.04Å; L298-V381 HydrophobicContact CD1-CG1 3.75Å; L298-V381 HydrophobicContact CD2-CG1 4.22Å
299	P	91.2	Very high	90	Very high	1 Å²	1	23.7 Å²	23.7	1%	0.006	12%	0.115	C	C	.	.	H	α-helix	trans	-59.7	-40.5	175.1	-25	36.6	0	0	0	112.3	I50 L53 M302 N303 T313	I50-P299 HydrophobicContact CD1-CB 3.61Å; I50-P299 HydrophobicContact CD1-CG 3.54Å; I50-P299 HydrophobicContact CG1-CG 4.41Å; L53-P299 HydrophobicContact CD1-CB 3.66Å; P299-M302 PolarHBondContact O-N 3.08Å; P299-N303 WeakPolarHBondContact O-CB 3.26Å; P299-N303 PolarHBondContact O-N 3.46Å; P299-T313 HydrophobicContact CB-CG2 3.8Å; P299-T313 WeakPolarHBondContact O-CG2 2.96Å
300	A	89.8	Confident	89.3	Confident	12 Å²	12	23.9 Å²	23.9	10%	0.099	12%	0.118	C	C	.	.	H	α-helix	trans	-62.9	-46.8	176.7	0	0	0	0	0	111.6	L53 Y297 L298 M302 N303 D304 W452	L53-A300 HydrophobicContact CD2-CB 3.93Å; Y297-A300 HydrophobicContact CD1-CB 4.06Å; Y297-A300 WeakPolarHBondContact O-CB 3.33Å; Y297-A300 PolarHBondContact O-N 2.85Å; Y297-A300 VanDerWaalsContact O-N 3.13Å; L298-A300 VanDerWaalsContact C-N 3.28Å; L298-A300 PolarHBondContact O-N 3.3Å; A300-M302 VanDerWaalsContact C-N 3.33Å; A300-M302 PolarHBondContact O-N 3.14Å; A300-N303 PolarHBondContact O-N 3.41Å; A300-D304 WeakPolarHBondContact O-CB 3.47Å; A300-D304 VanDerWaalsContact O-CG 3.25Å; A300-D304 PolarHBondContact O-N 2.92Å; A300-W452 HydrophobicContact CB-CZ2 4.32Å
301	Y	91.5	Very high	88.7	Confident	5 Å²	5	27 Å²	27	2%	0.02	13%	0.131	C	C	.	.	H	α-helix	trans	-57.3	-45	175.3	172.8	-110.4	0	0	0	112.9	Y297 L298 N303 V305 L306 T368 W452 F456	Y297-Y301 PolarHBondContact O-N 2.87Å; L298-Y301 HydrophobicContact CD1-CD1 4.35Å; L298-Y301 PolarHBondContact O-N 3.4Å; Y301-N303 VanDerWaalsContact C-N 3.32Å; Y301-N303 PolarHBondContact O-N 2.9Å; Y301-V305 HydrophobicContact CD2-CB 3.86Å; Y301-V305 HydrophobicContact CD2-CG1 4.48Å; Y301-V305 HydrophobicContact CD2-CG2 3.77Å; Y301-V305 HydrophobicContact CE2-CB 3.67Å; Y301-V305 HydrophobicContact CE2-CG1 3.79Å; Y301-V305 HydrophobicContact CE2-CG2 3.87Å; Y301-V305 WeakPolarHBondContact O-CB 3.46Å; Y301-V305 PolarHBondContact O-N 2.93Å; Y301-L306 HydrophobicContact CD1-CD1 4.34Å; Y301-L306 HydrophobicContact CD1-CG 4.46Å; Y301-L306 HydrophobicContact CE1-CD1 3.73Å; Y301-L306 HydrophobicContact CE1-CD2 4.31Å; Y301-L306 HydrophobicContact CE1-CG 3.9Å; Y301-L306 PolarHBondContact O-N 3.05Å; Y301-T368 HydrophobicContact CE1-CG2 4.17Å; Y301-T368 WeakPolarHBondContact OH-CG2 3.5Å; Y301-W452 HydrophobicContact CD2-CB 4.24Å; Y301-W452 AromaticContact CD2-CD2 3.63Å; Y301-W452 HydrophobicContact CD2-CD2 3.63Å; Y301-W452 AromaticContact CD2-CE3 3.85Å; Y301-W452 HydrophobicContact CD2-CE3 3.85Å; Y301-W452 AromaticContact CD2-CG 3.82Å; Y301-W452 HydrophobicContact CD2-CG 3.82Å; Y301-W452 HydrophobicContact CD2-CZ3 4.41Å; Y301-W452 HydrophobicContact CE2-CB 4.3Å; Y301-W452 HydrophobicContact CE2-CG 4.32Å; Y301-W452 HydrophobicContact CG-CD2 4.38Å; Y301-W452 HydrophobicContact CG-CE3 4.29Å; Y301-W452 HydrophobicContact CG-CZ3 4.43Å; Y301-F456 HydrophobicContact CD1-CZ 4.04Å; Y301-F456 AromaticContact CD2-CE2 3.96Å; Y301-F456 HydrophobicContact CD2-CE2 3.96Å; Y301-F456 AromaticContact CD2-CZ 3.77Å; Y301-F456 HydrophobicContact CD2-CZ 3.77Å; Y301-F456 HydrophobicContact CE1-CE2 4.33Å; Y301-F456 AromaticContact CE1-CZ 3.87Å; Y301-F456 HydrophobicContact CE1-CZ 3.87Å; Y301-F456 AromaticContact CE2-CE2 3.44Å; Y301-F456 HydrophobicContact CE2-CE2 3.44Å; Y301-F456 VanDerWaalsContact CE2-CE2 3.44Å; Y301-F456 AromaticContact CE2-CZ 3.6Å; Y301-F456 HydrophobicContact CE2-CZ 3.6Å; Y301-F456 AromaticContact CG-CZ 3.98Å; Y301-F456 HydrophobicContact CG-CZ 3.98Å; Y301-F456 AromaticContact CZ-CE2 3.65Å; Y301-F456 AromaticContact CZ-CZ 3.66Å
302	M	90.5	Very high	88.5	Confident	0 Å²	0	31.2 Å²	31.2	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-62.9	-38.3	179.7	-70.4	-81.7	163.1	0	0	111.9	L298 P299 A300 L306 H307 F308 T313 V316 T378	L298-M302 HydrophobicContact CD1-CE 3.59Å; L298-M302 HydrophobicContact CD1-CG 4.06Å; L298-M302 HydrophobicContact CG-CE 4.42Å; L298-M302 HydrophobicContact CG-CG 4.29Å; L298-M302 WeakPolarHBondContact O-CB 3.41Å; L298-M302 WeakPolarHBondContact O-CG 3.24Å; L298-M302 PolarHBondContact O-N 3.21Å; P299-M302 PolarHBondContact O-N 3.08Å; A300-M302 VanDerWaalsContact C-N 3.33Å; A300-M302 PolarHBondContact O-N 3.14Å; M302-L306 HydrophobicContact CE-CD1 3.95Å; M302-L306 CarbonylContact O-C 3.4Å; M302-L306 WeakPolarHBondContact O-CB 3.18Å; M302-L306 PolarHBondContact O-N 3.32Å; M302-L306 HydrophobicContact SD-CD1 3.57Å; M302-L306 VanDerWaalsContact SD-CD1 3.57Å; M302-H307 PolarHBondContact O-N 2.95Å; M302-F308 HydrophobicContact CB-CD2 4.02Å; M302-F308 PolarHBondContact O-N 3.36Å; M302-F308 HydrophobicContact SD-CD2 3.77Å; M302-F308 HydrophobicContact SD-CE2 3.67Å; M302-T313 HydrophobicContact CB-CG2 3.92Å; M302-V316 HydrophobicContact SD-CG1 4.07Å; M302-T378 HydrophobicContact CE-CG2 4.33Å
303	N	88.8	Confident	88.3	Confident	29 Å²	29	31 Å²	31	16%	0.155	15%	0.149	C	C	.	.	H	α-helix	trans	-78.2	-49.5	177.6	-178.6	-117.3	0	0	0	112.4	P299 A300 Y301 H307 F308	P299-N303 WeakPolarHBondContact O-CB 3.26Å; P299-N303 PolarHBondContact O-N 3.46Å; A300-N303 PolarHBondContact O-N 3.41Å; Y301-N303 VanDerWaalsContact C-N 3.32Å; Y301-N303 PolarHBondContact O-N 2.9Å; N303-H307 WeakPolarHBondContact O-CA 3.27Å; N303-H307 PolarHBondContact O-N 3.48Å; N303-F308 PolarHBondContact ND2-O 3.2Å
304	D	86.2	Confident	88	Confident	28 Å²	28	30.8 Å²	30.8	15%	0.15	15%	0.148	C	C	.	.	H	α-helix	trans	-71.4	-44.7	-172.7	-70.8	-23.3	0	0	0	112.4	A300 H307 K447	A300-D304 WeakPolarHBondContact O-CB 3.47Å; A300-D304 VanDerWaalsContact O-CG 3.25Å; A300-D304 PolarHBondContact O-N 2.92Å; D304-H307 PolarHBondContact O-CE1 2.88Å; D304-K447 HydrophobicContact CB-CB 4.02Å; D304-K447 WeakPolarHBondContact OD1-CD 3.35Å; D304-K447 WeakPolarHBondContact OD1-CE 3.25Å; D304-K447 IonicContact OD1-NZ 3.24Å; D304-K447 PolarHBondContact OD1-NZ 2.97Å; D304-K447 IonicContact OD2-NZ 3.44Å
305	V	86.8	Confident	88	Confident	19 Å²	19	35.2 Å²	35.2	12%	0.115	17%	0.167	C	C	.	.	T	Hydrogen-bonded Turn	trans	-103.9	-41.5	-172.7	-177.4	0	0	0	0	112.6	Y301 H307 I449 W452	Y301-V305 HydrophobicContact CD2-CB 3.86Å; Y301-V305 HydrophobicContact CD2-CG1 4.48Å; Y301-V305 HydrophobicContact CD2-CG2 3.77Å; Y301-V305 HydrophobicContact CE2-CB 3.67Å; Y301-V305 HydrophobicContact CE2-CG1 3.79Å; Y301-V305 HydrophobicContact CE2-CG2 3.87Å; Y301-V305 WeakPolarHBondContact O-CB 3.46Å; Y301-V305 PolarHBondContact O-N 2.93Å; V305-H307 VanDerWaalsContact C-N 3.29Å; V305-I449 HydrophobicContact CG1-CB 4.1Å; V305-I449 HydrophobicContact CG1-CD1 4.08Å; V305-I449 HydrophobicContact CG1-CG1 3.93Å; V305-W452 HydrophobicContact CG2-CB 4.4Å; V305-W452 HydrophobicContact CG2-CG 3.84Å
306	L	87.6	Confident	88.2	Confident	7 Å²	7	36.2 Å²	36.2	4%	0.037	17%	0.173	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.6	-2	-178.2	-56.2	-171.1	0	0	0	113	Y301 M302 F308 S374 A377	Y301-L306 HydrophobicContact CD1-CD1 4.34Å; Y301-L306 HydrophobicContact CD1-CG 4.46Å; Y301-L306 HydrophobicContact CE1-CD1 3.73Å; Y301-L306 HydrophobicContact CE1-CD2 4.31Å; Y301-L306 HydrophobicContact CE1-CG 3.9Å; Y301-L306 PolarHBondContact O-N 3.05Å; M302-L306 HydrophobicContact CE-CD1 3.95Å; M302-L306 CarbonylContact O-C 3.4Å; M302-L306 WeakPolarHBondContact O-CB 3.18Å; M302-L306 PolarHBondContact O-N 3.32Å; M302-L306 HydrophobicContact SD-CD1 3.57Å; M302-L306 VanDerWaalsContact SD-CD1 3.57Å; L306-F308 HydrophobicContact CB-CD2 3.74Å; L306-F308 HydrophobicContact CB-CE2 3.84Å; L306-F308 HydrophobicContact CD1-CD2 4.49Å; L306-F308 HydrophobicContact CD1-CE2 4.01Å; L306-F308 PolarHBondContact O-N 2.89Å; L306-S374 PolarHBondContact O-OG 2.7Å; L306-A377 HydrophobicContact CD1-CB 3.73Å; L306-A377 HydrophobicContact CD2-CB 3.79Å; L306-A377 HydrophobicContact CG-CB 4.43Å
307	H	85.3	Confident	88.3	Confident	156 Å²	156	35.8 Å²	35.8	72%	0.722	17%	0.17	S	C	*	.			trans	55.6	30.7	176	-53.1	-53.6	0	0	0	113.7	M302 N303 D304 V305	M302-H307 PolarHBondContact O-N 2.95Å; N303-H307 WeakPolarHBondContact O-CA 3.27Å; N303-H307 PolarHBondContact O-N 3.48Å; D304-H307 PolarHBondContact O-CE1 2.88Å; V305-H307 VanDerWaalsContact C-N 3.29Å
308	F	85.9	Confident	88.4	Confident	45 Å²	45	35.2 Å²	35.2	20%	0.197	17%	0.17	C	C	.	.			trans	-70.3	136.6	170.4	-74.1	-65.7	0	0	0	110.2	M302 N303 L306 T313 V316	M302-F308 HydrophobicContact CB-CD2 4.02Å; M302-F308 PolarHBondContact O-N 3.36Å; M302-F308 HydrophobicContact SD-CD2 3.77Å; M302-F308 HydrophobicContact SD-CE2 3.67Å; N303-F308 PolarHBondContact ND2-O 3.2Å; L306-F308 HydrophobicContact CB-CD2 3.74Å; L306-F308 HydrophobicContact CB-CE2 3.84Å; L306-F308 HydrophobicContact CD1-CD2 4.49Å; L306-F308 HydrophobicContact CD1-CE2 4.01Å; L306-F308 PolarHBondContact O-N 2.89Å; F308-T313 VanDerWaalsContact CB-OG1 3.31Å; F308-T313 WeakPolarHBondContact CB-OG1 3.49Å; F308-T313 PolarHBondContact O-OG1 2.86Å; F308-V316 HydrophobicContact CE2-CG1 4.34Å; F308-V316 HydrophobicContact CZ-CG1 4.46Å
309	E	86.7	Confident	88.5	Confident	111 Å²	111	38.9 Å²	38.9	52%	0.519	19%	0.188	S	C	.	.			trans	-54.8	150.2	167.3	-68.2	158.8	-151.2	0	0	110.7	Q311 K312 T313	E309-Q311 VanDerWaalsContact C-N 3.33Å; E309-Q311 PolarHBondContact O-N 3.44Å; E309-K312 HydrophobicContact CB-CB 4.4Å; E309-K312 HydrophobicContact CB-CD 4.33Å; E309-K312 HydrophobicContact CB-CG 4.44Å; E309-K312 PolarHBondContact O-N 3.48Å; E309-K312 IonicContact OE1-NZ 2.88Å; E309-K312 PolarHBondContact OE1-NZ 3.34Å; E309-K312 WeakPolarHBondContact OE2-CD 3.12Å; E309-K312 WeakPolarHBondContact OE2-CE 3.45Å; E309-K312 IonicContact OE2-NZ 2.82Å; E309-K312 PolarHBondContact OE2-NZ 3.43Å; E309-T313 WeakPolarHBondContact O-CB 3.38Å; E309-T313 PolarHBondContact O-N 3.14Å; E309-T313 PolarHBondContact O-OG1 3.36Å
310	L	81.7	Confident	88.6	Confident	21 Å²	21	38.9 Å²	38.9	11%	0.11	19%	0.188	C	C	.	.	H	α-helix	trans	-58.8	-41.5	-175.1	-72.2	168.5	0	0	0	113	L53 Y54 T59 T313 G314	L53-L310 HydrophobicContact CB-CD2 3.67Å; L53-L310 HydrophobicContact CD1-CD2 4.07Å; L53-L310 HydrophobicContact CG-CD2 4.43Å; Y54-L310 HydrophobicContact CD1-CD1 4.16Å; Y54-L310 HydrophobicContact CE1-CB 3.98Å; Y54-L310 HydrophobicContact CE1-CD1 4Å; Y54-L310 HydrophobicContact CE2-CB 4.33Å; Y54-L310 WeakPolarHBondContact OH-CB 3.38Å; Y54-L310 PolarHBondContact OH-O 2.89Å; T59-L310 HydrophobicContact CG2-CD1 3.31Å; L310-T313 WeakPolarHBondContact O-CB 3.13Å; L310-T313 PolarHBondContact O-N 3.38Å; L310-G314 PolarHBondContact O-N 2.88Å
311	Q	81.6	Confident	88.7	Confident	67 Å²	67	38.4 Å²	38.4	31%	0.313	18%	0.184	S	C	.	.	H	α-helix	trans	-62.3	-50.9	175.4	-169.8	-172.7	24.2	0	0	111.5	L203 E206 E309 T313 G314 F315	L203-Q311 HydrophobicContact CD2-CG 4.39Å; E206-Q311 HydrophobicContact CG-CB 4.26Å; E206-Q311 HydrophobicContact CG-CG 4.45Å; E309-Q311 VanDerWaalsContact C-N 3.33Å; E309-Q311 PolarHBondContact O-N 3.44Å; Q311-T313 VanDerWaalsContact C-N 3.28Å; Q311-T313 PolarHBondContact O-N 2.98Å; Q311-G314 PolarHBondContact O-N 2.99Å; Q311-F315 HydrophobicContact CG-CE2 4.34Å; Q311-F315 WeakPolarHBondContact O-CD2 3.32Å
312	K	88.2	Confident	88.8	Confident	101 Å²	101	42.1 Å²	42.1	44%	0.439	20%	0.204	S	C	.	.	H	α-helix	trans	-62.4	-37.1	179.8	-70.9	176.3	-177.6	147.9	0	111.7	E309 G314 F315 V316	E309-K312 HydrophobicContact CB-CB 4.4Å; E309-K312 HydrophobicContact CB-CD 4.33Å; E309-K312 HydrophobicContact CB-CG 4.44Å; E309-K312 PolarHBondContact O-N 3.48Å; E309-K312 IonicContact OE1-NZ 2.88Å; E309-K312 PolarHBondContact OE1-NZ 3.34Å; E309-K312 WeakPolarHBondContact OE2-CD 3.12Å; E309-K312 WeakPolarHBondContact OE2-CE 3.45Å; E309-K312 IonicContact OE2-NZ 2.82Å; E309-K312 PolarHBondContact OE2-NZ 3.43Å; K312-G314 VanDerWaalsContact C-N 3.25Å; K312-G314 PolarHBondContact O-N 3.31Å; K312-F315 PolarHBondContact O-N 3.28Å; K312-F315 VanDerWaalsContact O-N 3.14Å; K312-V316 WeakPolarHBondContact O-CB 3.18Å; K312-V316 WeakPolarHBondContact O-CG2 3.46Å; K312-V316 PolarHBondContact O-N 2.93Å
313	T	87.9	Confident	88.9	Confident	0 Å²	0	44 Å²	44	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-54.7	-41.7	176.2	-66.2	0	0	0	0	111.3	L53 P299 M302 F308 E309 L310 Q311 S317	L53-T313 HydrophobicContact CD1-CG2 4.24Å; P299-T313 HydrophobicContact CB-CG2 3.8Å; P299-T313 WeakPolarHBondContact O-CG2 2.96Å; M302-T313 HydrophobicContact CB-CG2 3.92Å; F308-T313 VanDerWaalsContact CB-OG1 3.31Å; F308-T313 WeakPolarHBondContact CB-OG1 3.49Å; F308-T313 PolarHBondContact O-OG1 2.86Å; E309-T313 WeakPolarHBondContact O-CB 3.38Å; E309-T313 PolarHBondContact O-N 3.14Å; E309-T313 PolarHBondContact O-OG1 3.36Å; L310-T313 WeakPolarHBondContact O-CB 3.13Å; L310-T313 PolarHBondContact O-N 3.38Å; Q311-T313 VanDerWaalsContact C-N 3.28Å; Q311-T313 PolarHBondContact O-N 2.98Å; T313-S317 WeakPolarHBondContact O-CB 3.5Å; T313-S317 PolarHBondContact O-N 3.41Å; T313-S317 PolarHBondContact O-OG 2.91Å
314	G	87.6	Confident	89.1	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-63.3	-43.7	177.2	0	0	0	0	0	113.6	I198 L310 Q311 K312 A318	I198-G314 WeakPolarHBondContact CG2-O 3.48Å; L310-G314 PolarHBondContact O-N 2.88Å; Q311-G314 PolarHBondContact O-N 2.99Å; K312-G314 VanDerWaalsContact C-N 3.25Å; K312-G314 PolarHBondContact O-N 3.31Å; G314-A318 PolarHBondContact O-N 3.38Å
315	F	90.9	Very high	89.3	Confident	102 Å²	102	42.1 Å²	42.1	45%	0.447	21%	0.209	S	C	.	.	H	α-helix	trans	-68.6	-46.9	177.8	-74.8	-85.2	0	0	0	112.2	P199 L203 Q311 K312 S317 A318	P199-F315 HydrophobicContact CB-CD1 3.88Å; P199-F315 HydrophobicContact CB-CE1 4.01Å; P199-F315 HydrophobicContact CB-CG 4.25Å; P199-F315 HydrophobicContact CB-CZ 4.48Å; L203-F315 HydrophobicContact CD1-CE2 4.48Å; L203-F315 HydrophobicContact CD1-CZ 3.84Å; L203-F315 HydrophobicContact CD2-CE2 3.75Å; L203-F315 HydrophobicContact CD2-CZ 3.83Å; L203-F315 HydrophobicContact CG-CE2 3.98Å; L203-F315 HydrophobicContact CG-CZ 3.85Å; Q311-F315 HydrophobicContact CG-CE2 4.34Å; Q311-F315 WeakPolarHBondContact O-CD2 3.32Å; K312-F315 PolarHBondContact O-N 3.28Å; K312-F315 VanDerWaalsContact O-N 3.14Å; F315-S317 VanDerWaalsContact C-N 3.35Å; F315-S317 PolarHBondContact O-N 3.3Å; F315-A318 WeakPolarHBondContact O-CB 3.18Å; F315-A318 PolarHBondContact O-N 3Å
316	V	92.4	Very high	89.5	Confident	28 Å²	28	45.6 Å²	45.6	17%	0.17	23%	0.226	C	C	.	.	H	α-helix	trans	-66.4	-39.4	-178.1	176.3	0	0	0	0	110.9	M302 F308 K312 A318 I319 P320 T378	M302-V316 HydrophobicContact SD-CG1 4.07Å; F308-V316 HydrophobicContact CE2-CG1 4.34Å; F308-V316 HydrophobicContact CZ-CG1 4.46Å; K312-V316 WeakPolarHBondContact O-CB 3.18Å; K312-V316 WeakPolarHBondContact O-CG2 3.46Å; K312-V316 PolarHBondContact O-N 2.93Å; V316-A318 PolarHBondContact O-N 3.29Å; V316-I319 WeakPolarHBondContact O-CB 3.49Å; V316-I319 PolarHBondContact O-N 2.83Å; V316-P320 VanDerWaalsContact O-CD 3.32Å; V316-P320 WeakPolarHBondContact O-CD 3.35Å; V316-T378 HydrophobicContact CG1-CG2 3.41Å; V316-T378 VanDerWaalsContact CG1-CG2 3.41Å
317	S	91	Very high	89.7	Confident	0 Å²	0	47 Å²	47	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-68	-17	179.3	-59.7	0	0	0	0	113.5	T313 F315 Y321	T313-S317 WeakPolarHBondContact O-CB 3.5Å; T313-S317 PolarHBondContact O-N 3.41Å; T313-S317 PolarHBondContact O-OG 2.91Å; F315-S317 VanDerWaalsContact C-N 3.35Å; F315-S317 PolarHBondContact O-N 3.3Å; S317-Y321 WeakPolarHBondContact O-CD2 3.2Å; S317-Y321 WeakPolarHBondContact O-CE2 3.44Å
318	A	92.5	Very high	90	Very high	7 Å²	7	41 Å²	41	6%	0.058	21%	0.207	C	C	.	.	H	α-helix	trans	-77.2	-27.5	175.1	0	0	0	0	0	112.9	P199 G314 F315 V316 Y321 L322	P199-A318 HydrophobicContact CG-CB 4.33Å; G314-A318 PolarHBondContact O-N 3.38Å; F315-A318 WeakPolarHBondContact O-CB 3.18Å; F315-A318 PolarHBondContact O-N 3Å; V316-A318 PolarHBondContact O-N 3.29Å; A318-Y321 PolarHBondContact O-N 3.47Å; A318-L322 PolarHBondContact O-N 3.1Å
319	I	93.6	Very high	90	Very high	78 Å²	78	44.2 Å²	44.2	40%	0.4	22%	0.222	S	C	.	.	H	α-helix	trans	-61.7	-44.5	-172.9	-56.3	172.3	0	0	0	112.5	V316 Y321 L322 T323	V316-I319 WeakPolarHBondContact O-CB 3.49Å; V316-I319 PolarHBondContact O-N 2.83Å; I319-Y321 VanDerWaalsContact C-N 3.34Å; I319-Y321 PolarHBondContact O-N 3.3Å; I319-L322 PolarHBondContact O-N 3.25Å; I319-T323 WeakPolarHBondContact O-CB 3.33Å; I319-T323 PolarHBondContact O-N 2.88Å; I319-T323 PolarHBondContact O-OG1 3.47Å
320	P	93.8	Very high	90.1	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-60.1	-40.4	177.8	-25.3	35.2	0	0	0	113.2	L298 V316 T323 M324 V381 V385	L298-P320 HydrophobicContact CD2-CB 4.45Å; L298-P320 HydrophobicContact CD2-CG 3.95Å; V316-P320 VanDerWaalsContact O-CD 3.32Å; V316-P320 WeakPolarHBondContact O-CD 3.35Å; P320-T323 WeakPolarHBondContact O-CB 3.23Å; P320-T323 PolarHBondContact O-N 2.85Å; P320-M324 PolarHBondContact O-N 2.95Å; P320-V381 HydrophobicContact CB-CG1 4.32Å; P320-V381 HydrophobicContact CG-CG1 4Å; P320-V385 HydrophobicContact CB-CB 3.76Å; P320-V385 HydrophobicContact CB-CG1 3.94Å; P320-V385 HydrophobicContact CB-CG2 4.09Å
321	Y	92.5	Very high	90.5	Very high	2 Å²	2	41.1 Å²	41.1	1%	0.008	21%	0.212	C	C	.	.	H	α-helix	trans	-74	-32.4	178.7	-53.9	-66.2	0	0	0	112.7	T194 I198 F291 M294 L295 L298 S317 A318 I319 T323 M324 G325 V385	T194-Y321 HydrophobicContact CG2-CD1 4.49Å; T194-Y321 HydrophobicContact CG2-CD2 3.99Å; T194-Y321 HydrophobicContact CG2-CG 3.91Å; I198-Y321 HydrophobicContact CD1-CD2 3.63Å; I198-Y321 HydrophobicContact CD1-CE2 3.74Å; F291-Y321 HydrophobicContact CD2-CE1 4.46Å; F291-Y321 HydrophobicContact CE2-CD1 4.03Å; F291-Y321 HydrophobicContact CE2-CE1 4.15Å; M294-Y321 PolarHBondContact O-OH 3.06Å; L295-Y321 WeakPolarHBondContact CA-OH 3.16Å; L295-Y321 HydrophobicContact CD1-CD1 4.36Å; L295-Y321 HydrophobicContact CD1-CE1 3.86Å; L295-Y321 HydrophobicContact CD1-CE2 4.32Å; L295-Y321 PolarHBondContact N-OH 3.4Å; L298-Y321 HydrophobicContact CD2-CE2 4.04Å; S317-Y321 WeakPolarHBondContact O-CD2 3.2Å; S317-Y321 WeakPolarHBondContact O-CE2 3.44Å; A318-Y321 PolarHBondContact O-N 3.47Å; I319-Y321 VanDerWaalsContact C-N 3.34Å; I319-Y321 PolarHBondContact O-N 3.3Å; Y321-T323 VanDerWaalsContact C-N 3.35Å; Y321-M324 PolarHBondContact O-N 3.05Å; Y321-G325 PolarHBondContact O-N 3.38Å; Y321-V385 HydrophobicContact CD1-CG1 3.98Å; Y321-V385 HydrophobicContact CE1-CG1 4.01Å
322	L	92.7	Very high	90.6	Very high	83 Å²	83	40 Å²	40	44%	0.435	22%	0.218	S	C	.	.	H	α-helix	trans	-63.2	-45.7	170.5	175.7	59	0	0	0	110.3	V195 A318 I319 M324 G325 I326	V195-L322 HydrophobicContact CG1-CB 4.04Å; V195-L322 HydrophobicContact CG1-CD1 4.24Å; V195-L322 HydrophobicContact CG2-CB 3.83Å; A318-L322 PolarHBondContact O-N 3.1Å; I319-L322 PolarHBondContact O-N 3.25Å; L322-M324 VanDerWaalsContact C-N 3.31Å; L322-M324 PolarHBondContact O-N 3.11Å; L322-G325 PolarHBondContact O-N 2.92Å; L322-I326 HydrophobicContact CD1-CD1 4.1Å; L322-I326 HydrophobicContact CD1-CG1 4.37Å; L322-I326 HydrophobicContact CG-CD1 4.07Å; L322-I326 WeakPolarHBondContact O-CG1 3.28Å; L322-I326 PolarHBondContact O-N 2.94Å
323	T	93.9	Very high	90.6	Very high	40 Å²	40	40.8 Å²	40.8	25%	0.245	23%	0.226	C	C	.	.	H	α-helix	trans	-59.8	-43.2	176.2	-53.5	0	0	0	0	110.8	I319 P320 Y321 I326 L327	I319-T323 WeakPolarHBondContact O-CB 3.33Å; I319-T323 PolarHBondContact O-N 2.88Å; I319-T323 PolarHBondContact O-OG1 3.47Å; P320-T323 WeakPolarHBondContact O-CB 3.23Å; P320-T323 PolarHBondContact O-N 2.85Å; Y321-T323 VanDerWaalsContact C-N 3.35Å; T323-I326 PolarHBondContact O-N 3.38Å; T323-L327 HydrophobicContact CG2-CD1 4Å; T323-L327 HydrophobicContact CG2-CG 4.42Å; T323-L327 WeakPolarHBondContact O-CB 3.4Å; T323-L327 WeakPolarHBondContact O-CG 3.14Å; T323-L327 PolarHBondContact O-N 3.48Å
324	M	93.1	Very high	90.7	Very high	1 Å²	1	43.7 Å²	43.7	1%	0.005	24%	0.241	C	C	.	.	H	α-helix	trans	-60.3	-45.6	175	-172.5	-170.2	-177.5	0	0	112	Y191 E287 F291 P320 Y321 L322 I326 L327 L328 V385 W392	Y191-M324 HydrophobicContact CD1-SD 4.45Å; Y191-M324 HydrophobicContact CE1-CE 3.99Å; Y191-M324 HydrophobicContact CE1-CG 4.48Å; Y191-M324 HydrophobicContact CE1-SD 3.92Å; E287-M324 WeakPolarHBondContact OE1-CE 3.43Å; F291-M324 HydrophobicContact CD2-CE 3.94Å; F291-M324 HydrophobicContact CD2-SD 3.75Å; F291-M324 HydrophobicContact CE2-CE 4.27Å; F291-M324 HydrophobicContact CE2-SD 3.78Å; P320-M324 PolarHBondContact O-N 2.95Å; Y321-M324 PolarHBondContact O-N 3.05Å; L322-M324 VanDerWaalsContact C-N 3.31Å; L322-M324 PolarHBondContact O-N 3.11Å; M324-I326 PolarHBondContact O-N 3.4Å; M324-L327 PolarHBondContact O-N 3.06Å; M324-L328 VanDerWaalsContact O-CB 3.32Å; M324-L328 WeakPolarHBondContact O-CB 3.03Å; M324-L328 PolarHBondContact O-N 3.44Å; M324-V385 HydrophobicContact CB-CG1 4.33Å; M324-V385 WeakPolarHBondContact CG-O 3.4Å; M324-V385 HydrophobicContact SD-CG1 4.37Å; M324-W392 HydrophobicContact CE-CE3 4.46Å
325	G	89.3	Confident	90.8	Very high	17 Å²	17	44.3 Å²	44.3	18%	0.175	25%	0.246	C	C	.	.	H	α-helix	trans	-60.8	-42.8	176.6	0	0	0	0	0	112.6	Y321 L322 Q329	Y321-G325 PolarHBondContact O-N 3.38Å; L322-G325 PolarHBondContact O-N 2.92Å; G325-Q329 WeakPolarHBondContact O-CG 3.38Å; G325-Q329 PolarHBondContact O-N 2.89Å
326	I	91.3	Very high	90.6	Very high	92 Å²	92	45.5 Å²	45.5	47%	0.472	25%	0.253	S	S	.	.	H	α-helix	trans	-64.7	-49	176.3	-66.9	166.7	0	0	0	110.6	L322 T323 M324 L328 Q329 V330	L322-I326 HydrophobicContact CD1-CD1 4.1Å; L322-I326 HydrophobicContact CD1-CG1 4.37Å; L322-I326 HydrophobicContact CG-CD1 4.07Å; L322-I326 WeakPolarHBondContact O-CG1 3.28Å; L322-I326 PolarHBondContact O-N 2.94Å; T323-I326 PolarHBondContact O-N 3.38Å; M324-I326 PolarHBondContact O-N 3.4Å; I326-L328 VanDerWaalsContact C-N 3.29Å; I326-L328 PolarHBondContact O-N 3.23Å; I326-Q329 PolarHBondContact O-N 2.84Å; I326-V330 HydrophobicContact CG2-CG2 4.27Å; I326-V330 WeakPolarHBondContact O-CG2 3.4Å; I326-V330 PolarHBondContact O-N 3.39Å
327	L	92.6	Very high	90.5	Very high	36 Å²	36	47.5 Å²	47.5	19%	0.188	27%	0.267	C	S	.	.	H	α-helix	trans	-66.6	-30	-178	-73.8	178.9	0	0	0	112.8	T323 M324 Q329 V330 S331 G386 F387 I390	T323-L327 HydrophobicContact CG2-CD1 4Å; T323-L327 HydrophobicContact CG2-CG 4.42Å; T323-L327 WeakPolarHBondContact O-CB 3.4Å; T323-L327 WeakPolarHBondContact O-CG 3.14Å; T323-L327 PolarHBondContact O-N 3.48Å; M324-L327 PolarHBondContact O-N 3.06Å; L327-Q329 VanDerWaalsContact C-N 3.31Å; L327-Q329 PolarHBondContact O-N 3.13Å; L327-V330 PolarHBondContact O-N 2.9Å; L327-S331 WeakPolarHBondContact O-CB 3.37Å; L327-S331 PolarHBondContact O-N 2.96Å; L327-G386 WeakPolarHBondContact CB-O 3.34Å; L327-G386 WeakPolarHBondContact CD1-O 3.22Å; L327-F387 HydrophobicContact CD1-CD2 4.03Å; L327-F387 HydrophobicContact CD1-CE2 4.36Å; L327-I390 HydrophobicContact CB-CG1 4.32Å
328	L	90.3	Very high	90.4	Very high	30 Å²	30	48.6 Å²	48.6	16%	0.157	27%	0.273	C	S	.	.	H	α-helix	trans	-63	-35.4	170.3	179	65.1	0	0	0	112.4	Y191 M324 I326 S331 G389 W392	Y191-L328 HydrophobicContact CD2-CD2 4.05Å; Y191-L328 HydrophobicContact CE2-CD2 3.33Å; M324-L328 VanDerWaalsContact O-CB 3.32Å; M324-L328 WeakPolarHBondContact O-CB 3.03Å; M324-L328 PolarHBondContact O-N 3.44Å; I326-L328 VanDerWaalsContact C-N 3.29Å; I326-L328 PolarHBondContact O-N 3.23Å; L328-S331 PolarHBondContact O-OG 3.36Å; L328-G389 VanDerWaalsContact CD1-O 3.31Å; L328-G389 WeakPolarHBondContact CD1-O 3.48Å; L328-W392 HydrophobicContact CD1-CB 4.38Å; L328-W392 HydrophobicContact CD1-CG 4.47Å
329	Q	86	Confident	90.2	Very high	113 Å²	113	51.4 Å²	51.4	53%	0.528	29%	0.285	S	S	.	.	H	α-helix	trans	-76	-40.6	175.5	-62	-56.9	123.5	0	0	111.4	G325 I326 L327 S331	G325-Q329 WeakPolarHBondContact O-CG 3.38Å; G325-Q329 PolarHBondContact O-N 2.89Å; I326-Q329 PolarHBondContact O-N 2.84Å; L327-Q329 VanDerWaalsContact C-N 3.31Å; L327-Q329 PolarHBondContact O-N 3.13Å; Q329-S331 VanDerWaalsContact C-N 3.32Å; Q329-S331 PolarHBondContact O-N 2.67Å
330	V	89.4	Confident	89.9	Confident	66 Å²	66	55.7 Å²	55.7	40%	0.4	30%	0.301	S	S	.	.	H	α-helix	trans	-66.9	-33	178.5	173.1	0	0	0	0	111.6	I326 L327 G332 I333 L334	I326-V330 HydrophobicContact CG2-CG2 4.27Å; I326-V330 WeakPolarHBondContact O-CG2 3.4Å; I326-V330 PolarHBondContact O-N 3.39Å; L327-V330 PolarHBondContact O-N 2.9Å; V330-G332 VanDerWaalsContact C-N 3.25Å; V330-G332 PolarHBondContact O-N 2.98Å; V330-I333 PolarHBondContact O-N 2.89Å; V330-I333 VanDerWaalsContact O-N 3.08Å; V330-L334 WeakPolarHBondContact O-CB 3.34Å; V330-L334 PolarHBondContact O-N 3.5Å
331	S	89.5	Confident	89.8	Confident	1 Å²	1	63.5 Å²	63.5	1%	0.007	34%	0.335	C	S	.	.	H	α-helix	trans	-58.2	-35.6	-177.8	68.4	0	0	0	0	112.9	L327 L328 Q329 L334 A335 S393	L327-S331 WeakPolarHBondContact O-CB 3.37Å; L327-S331 PolarHBondContact O-N 2.96Å; L328-S331 PolarHBondContact O-OG 3.36Å; Q329-S331 VanDerWaalsContact C-N 3.32Å; Q329-S331 PolarHBondContact O-N 2.67Å; S331-L334 PolarHBondContact O-N 2.91Å; S331-A335 VanDerWaalsContact O-CB 3.28Å; S331-A335 WeakPolarHBondContact O-CB 3.28Å; S331-A335 PolarHBondContact O-N 3Å; S331-S393 WeakPolarHBondContact OG-CB 3.36Å; S331-S393 PolarHBondContact OG-OG 2.61Å
332	G	84.5	Confident	89.7	Confident	44 Å²	44	69.2 Å²	69.2	45%	0.454	36%	0.36	S	S	.	.	H	α-helix	trans	-64.8	-42.4	176.7	0	0	0	0	0	112.5	V330 H336	V330-G332 VanDerWaalsContact C-N 3.25Å; V330-G332 PolarHBondContact O-N 2.98Å; G332-H336 PolarHBondContact O-N 2.88Å
333	I	88.2	Confident	89.5	Confident	116 Å²	116	73.1 Å²	73.1	60%	0.595	38%	0.376	S	S	*	.	H	α-helix	trans	-68.6	-44.5	175.8	-59.1	171.6	0	0	0	109.7	V330 A335 H336 C337	V330-I333 PolarHBondContact O-N 2.89Å; V330-I333 VanDerWaalsContact O-N 3.08Å; I333-A335 VanDerWaalsContact C-N 3.35Å; I333-A335 PolarHBondContact O-N 2.89Å; I333-H336 WeakPolarHBondContact O-CB 3.33Å; I333-H336 PolarHBondContact O-N 3.29Å; I333-H336 VanDerWaalsContact O-N 3.16Å; I333-C337 PolarHBondContact O-N 3.32Å; I333-C337 PolarHBondContact O-SG 2.96Å; I333-C337 VanDerWaalsContact O-SG 3.39Å
334	L	90	Very high	89.2	Confident	62 Å²	62	73.6 Å²	73.6	33%	0.325	38%	0.377	S	S	.	.	H	α-helix	trans	-58	-46.9	178	-179	62.2	0	0	0	111.3	V330 S331 H336 C337 I338 M353 I390	V330-L334 WeakPolarHBondContact O-CB 3.34Å; V330-L334 PolarHBondContact O-N 3.5Å; S331-L334 PolarHBondContact O-N 2.91Å; L334-H336 VanDerWaalsContact C-N 3.31Å; L334-H336 PolarHBondContact O-N 2.97Å; L334-C337 PolarHBondContact O-N 3.35Å; L334-I338 HydrophobicContact CD1-CD1 3.94Å; L334-I338 HydrophobicContact CD1-CG1 4.24Å; L334-I338 HydrophobicContact CG-CD1 3.84Å; L334-I338 VanDerWaalsContact O-CG1 3.3Å; L334-I338 WeakPolarHBondContact O-CG1 3.4Å; L334-I338 PolarHBondContact O-N 3.49Å; L334-M353 HydrophobicContact CD2-CE 4.11Å; L334-M353 HydrophobicContact CD2-SD 4.32Å; L334-M353 HydrophobicContact CG-CE 4.41Å; L334-I390 HydrophobicContact CD2-CD1 4.44Å
335	A	89.1	Confident	88.9	Confident	13 Å²	13	83.2 Å²	83.2	11%	0.107	41%	0.413	C	S	.	.	H	α-helix	trans	-59.6	-41.7	177	0	0	0	0	0	111.7	S331 I333 Q339 L349 M353	S331-A335 VanDerWaalsContact O-CB 3.28Å; S331-A335 WeakPolarHBondContact O-CB 3.28Å; S331-A335 PolarHBondContact O-N 3Å; I333-A335 VanDerWaalsContact C-N 3.35Å; I333-A335 PolarHBondContact O-N 2.89Å; A335-Q339 VanDerWaalsContact O-CB 3.3Å; A335-Q339 WeakPolarHBondContact O-CB 3.26Å; A335-Q339 PolarHBondContact O-N 3.18Å; A335-L349 HydrophobicContact CB-CD2 4.36Å; A335-M353 HydrophobicContact CB-SD 4.46Å
336	H	86.9	Confident	88.8	Confident	126 Å²	126	85.4 Å²	85.4	58%	0.583	42%	0.42	S	S	*	.	H	α-helix	trans	-64.6	-45.4	176	-176	74	0	0	0	112.4	G332 I333 L334 Q339 K340	G332-H336 PolarHBondContact O-N 2.88Å; I333-H336 WeakPolarHBondContact O-CB 3.33Å; I333-H336 PolarHBondContact O-N 3.29Å; I333-H336 VanDerWaalsContact O-N 3.16Å; L334-H336 VanDerWaalsContact C-N 3.31Å; L334-H336 PolarHBondContact O-N 2.97Å; H336-Q339 PolarHBondContact O-N 3.46Å; H336-K340 WeakPolarHBondContact O-CB 3.49Å; H336-K340 PolarHBondContact O-N 2.87Å
337	C	90.2	Very high	88.6	Confident	70 Å²	70	82.6 Å²	82.6	47%	0.473	41%	0.408	S	S	.	.	H	α-helix	trans	-62.5	-44.3	178.3	-71.1	0	0	0	0	112.2	I333 L334 K340 K341	I333-C337 PolarHBondContact O-N 3.32Å; I333-C337 PolarHBondContact O-SG 2.96Å; I333-C337 VanDerWaalsContact O-SG 3.39Å; L334-C337 PolarHBondContact O-N 3.35Å; C337-K340 PolarHBondContact O-N 3.38Å; C337-K341 VanDerWaalsContact O-CB 3.31Å; C337-K341 WeakPolarHBondContact O-CB 3.47Å; C337-K341 PolarHBondContact O-N 3.46Å
338	I	89.9	Confident	88.6	Confident	24 Å²	24	85 Å²	85	12%	0.123	42%	0.419	C	S	.	.	H	α-helix	trans	-62.3	-45.6	176.2	-67.4	169.3	0	0	0	110.1	L334 K340 K341 F342 L344 L349 L352 M353	L334-I338 HydrophobicContact CD1-CD1 3.94Å; L334-I338 HydrophobicContact CD1-CG1 4.24Å; L334-I338 HydrophobicContact CG-CD1 3.84Å; L334-I338 VanDerWaalsContact O-CG1 3.3Å; L334-I338 WeakPolarHBondContact O-CG1 3.4Å; L334-I338 PolarHBondContact O-N 3.49Å; I338-K340 PolarHBondContact O-N 3.03Å; I338-K341 PolarHBondContact O-N 3.41Å; I338-F342 HydrophobicContact CG2-CD2 4.11Å; I338-F342 PolarHBondContact O-N 2.86Å; I338-L344 HydrophobicContact CG2-CD1 3.78Å; I338-L349 HydrophobicContact CB-CD1 3.99Å; I338-L349 HydrophobicContact CG2-CD1 3.64Å; I338-L352 HydrophobicContact CD1-CD2 4.22Å; I338-L352 HydrophobicContact CG2-CD2 4.36Å; I338-M353 HydrophobicContact CD1-CE 3.52Å
339	Q	87	Confident	88.6	Confident	65 Å²	65	83.8 Å²	83.8	30%	0.304	41%	0.413	S	S	.	.	H	α-helix	trans	-62.1	-42.2	179	-170.2	62.4	39.3	0	0	112	A335 H336 Q343 L344 L349	A335-Q339 VanDerWaalsContact O-CB 3.3Å; A335-Q339 WeakPolarHBondContact O-CB 3.26Å; A335-Q339 PolarHBondContact O-N 3.18Å; H336-Q339 PolarHBondContact O-N 3.46Å; Q339-Q343 VanDerWaalsContact O-CA 3.24Å; Q339-Q343 WeakPolarHBondContact O-CA 3.42Å; Q339-Q343 PolarHBondContact O-N 2.97Å; Q339-L344 PolarHBondContact NE2-O 3.45Å; Q339-L344 PolarHBondContact OE1-O 3.4Å; Q339-L349 HydrophobicContact CB-CD2 4.27Å
340	K	88.7	Confident	88.9	Confident	169 Å²	169	80 Å²	80	74%	0.735	39%	0.394	S	S	*	.	H	α-helix	trans	-68.2	-40.7	179.1	-174.1	178.4	178.4	-178.5	0	112.3	H336 C337 I338	H336-K340 WeakPolarHBondContact O-CB 3.49Å; H336-K340 PolarHBondContact O-N 2.87Å; C337-K340 PolarHBondContact O-N 3.38Å; I338-K340 PolarHBondContact O-N 3.03Å
341	K	91.3	Very high	89.1	Confident	164 Å²	164	79.2 Å²	79.2	71%	0.713	39%	0.385	S	S	*	.	H	α-helix	trans	-78.2	-43.6	-175.4	-175.3	173.7	179.1	178	0	113.1	C337 I338	C337-K341 VanDerWaalsContact O-CB 3.31Å; C337-K341 WeakPolarHBondContact O-CB 3.47Å; C337-K341 PolarHBondContact O-N 3.46Å; I338-K341 PolarHBondContact O-N 3.41Å
342	F	89.5	Confident	89.3	Confident	121 Å²	121	83.1 Å²	83.1	53%	0.531	41%	0.406	S	S	.	.	H	α-helix	trans	-108.2	-8.4	-171.2	-63.7	-74.5	0	0	0	113.9	I338 L344	I338-F342 HydrophobicContact CG2-CD2 4.11Å; I338-F342 PolarHBondContact O-N 2.86Å; F342-L344 HydrophobicContact CB-CD1 4.26Å; F342-L344 HydrophobicContact CB-CD2 3.87Å; F342-L344 HydrophobicContact CB-CG 3.69Å; F342-L344 PolarHBondContact O-N 3.28Å
343	Q	88.5	Confident	89.7	Confident	166 Å²	166	81.6 Å²	81.6	78%	0.776	39%	0.387	S	S	*	.			trans	48.4	37.3	179.7	-61.6	-172.7	-35.1	0	0	113.6	Q339	Q339-Q343 VanDerWaalsContact O-CA 3.24Å; Q339-Q343 WeakPolarHBondContact O-CA 3.42Å; Q339-Q343 PolarHBondContact O-N 2.97Å
344	L	87.4	Confident	90	Very high	50 Å²	50	76 Å²	76	26%	0.262	36%	0.358	S	S	.	.			trans	-63.3	152.8	-175.5	-60	177.5	0	0	0	111.3	I338 Q339 F342 L346 I348	I338-L344 HydrophobicContact CG2-CD1 3.78Å; Q339-L344 PolarHBondContact NE2-O 3.45Å; Q339-L344 PolarHBondContact OE1-O 3.4Å; F342-L344 HydrophobicContact CB-CD1 4.26Å; F342-L344 HydrophobicContact CB-CD2 3.87Å; F342-L344 HydrophobicContact CB-CG 3.69Å; F342-L344 PolarHBondContact O-N 3.28Å; L344-L346 PolarHBondContact O-N 2.93Å; L344-I348 HydrophobicContact CB-CB 4.47Å; L344-I348 HydrophobicContact CD1-CG2 4.24Å
345	R	87.8	Confident	90.3	Very high	202 Å²	202	73.1 Å²	73.1	76%	0.762	34%	0.343	S	S	*	.			trans	-59.4	139.7	165.1	-64.3	-178.2	-179.7	-180	0.4	108.7	V347 I348 L349	R345-V347 PolarHBondContact O-N 3.48Å; R345-V347 VanDerWaalsContact O-N 3.14Å; R345-I348 HydrophobicContact CB-CD1 4.01Å; R345-I348 HydrophobicContact CB-CG1 4.15Å; R345-I348 HydrophobicContact CG-CD1 4.37Å; R345-I348 WeakPolarHBondContact O-CA 3.47Å; R345-I348 WeakPolarHBondContact O-CB 3.46Å; R345-I348 PolarHBondContact O-N 2.9Å; R345-L349 PolarHBondContact O-N 3.38Å; R345-L349 VanDerWaalsContact O-N 3.14Å
346	L	86.8	Confident	90.6	Very high	64 Å²	64	73.6 Å²	73.6	34%	0.335	35%	0.35	S	S	.	.	H	α-helix	trans	-53.6	-40.7	-176.2	-173.3	59.9	0	0	0	112.6	L344 I348 L349 R350 D401 A476	L344-L346 PolarHBondContact O-N 2.93Å; L346-I348 VanDerWaalsContact C-N 3.3Å; L346-I348 PolarHBondContact O-N 3.15Å; L346-L349 HydrophobicContact CD1-CD2 4.48Å; L346-L349 WeakPolarHBondContact O-CB 3.34Å; L346-L349 PolarHBondContact O-N 3.22Å; L346-R350 WeakPolarHBondContact O-CG 3.17Å; L346-R350 PolarHBondContact O-N 3.37Å; L346-D401 HydrophobicContact CD2-CB 4.28Å; L346-A476 HydrophobicContact CB-CB 4.45Å; L346-A476 HydrophobicContact CD2-CB 4.32Å; L346-A476 HydrophobicContact CG-CB 4.12Å
347	V	88	Confident	91.1	Very high	33 Å²	33	67.7 Å²	67.7	20%	0.2	32%	0.323	C	S	.	.	H	α-helix	trans	-56.3	-43.7	175.6	-169.9	0	0	0	0	112	R345 R350 K351 A474 A476	R345-V347 PolarHBondContact O-N 3.48Å; R345-V347 VanDerWaalsContact O-N 3.14Å; V347-R350 PolarHBondContact O-N 3.48Å; V347-K351 HydrophobicContact CG1-CD 4.19Å; V347-K351 HydrophobicContact CG1-CG 4.45Å; V347-K351 WeakPolarHBondContact O-CB 3.44Å; V347-K351 WeakPolarHBondContact O-CG 3.34Å; V347-K351 PolarHBondContact O-N 2.76Å; V347-A474 WeakPolarHBondContact CG1-O 3.27Å; V347-A476 HydrophobicContact CB-CB 4.27Å; V347-A476 HydrophobicContact CG2-CB 3.74Å
348	I	92	Very high	91.4	Very high	85 Å²	85	64.4 Å²	64.4	44%	0.436	30%	0.3	S	S	.	.	H	α-helix	trans	-67.1	-42.1	-178.9	-59.8	173.9	0	0	0	109.3	L344 R345 L346 R350 K351 L352	L344-I348 HydrophobicContact CB-CB 4.47Å; L344-I348 HydrophobicContact CD1-CG2 4.24Å; R345-I348 HydrophobicContact CB-CD1 4.01Å; R345-I348 HydrophobicContact CB-CG1 4.15Å; R345-I348 HydrophobicContact CG-CD1 4.37Å; R345-I348 WeakPolarHBondContact O-CA 3.47Å; R345-I348 WeakPolarHBondContact O-CB 3.46Å; R345-I348 PolarHBondContact O-N 2.9Å; L346-I348 VanDerWaalsContact C-N 3.3Å; L346-I348 PolarHBondContact O-N 3.15Å; I348-R350 PolarHBondContact O-N 2.89Å; I348-K351 PolarHBondContact O-N 3.05Å; I348-L352 WeakPolarHBondContact O-CB 3.32Å; I348-L352 PolarHBondContact O-N 3.19Å
349	L	90.6	Very high	91.8	Very high	5 Å²	5	66.7 Å²	66.7	3%	0.026	31%	0.312	C	S	.	.	H	α-helix	trans	-59.7	-45.9	174	-179.5	66.3	0	0	0	111.5	A335 I338 Q339 R345 L346 L352 M353	A335-L349 HydrophobicContact CB-CD2 4.36Å; I338-L349 HydrophobicContact CB-CD1 3.99Å; I338-L349 HydrophobicContact CG2-CD1 3.64Å; Q339-L349 HydrophobicContact CB-CD2 4.27Å; R345-L349 PolarHBondContact O-N 3.38Å; R345-L349 VanDerWaalsContact O-N 3.14Å; L346-L349 HydrophobicContact CD1-CD2 4.48Å; L346-L349 WeakPolarHBondContact O-CB 3.34Å; L346-L349 PolarHBondContact O-N 3.22Å; L349-L352 PolarHBondContact O-N 2.9Å; L349-M353 HydrophobicContact CD1-CG 4.28Å; L349-M353 VanDerWaalsContact O-CG 3.29Å; L349-M353 WeakPolarHBondContact O-CG 3.45Å; L349-M353 PolarHBondContact O-N 2.91Å
350	R	90.9	Very high	92.3	Very high	35 Å²	35	65.4 Å²	65.4	13%	0.132	31%	0.309	C	S	.	.	H	α-helix	trans	-63.6	-43	177.8	-62.8	-49	-176	-158.8	-2.2	112.1	L346 V347 I348 M353 T354 T397 N398 D401 A476	L346-R350 WeakPolarHBondContact O-CG 3.17Å; L346-R350 PolarHBondContact O-N 3.37Å; V347-R350 PolarHBondContact O-N 3.48Å; I348-R350 PolarHBondContact O-N 2.89Å; R350-M353 PolarHBondContact O-N 3.44Å; R350-T354 WeakPolarHBondContact O-CB 3.33Å; R350-T354 PolarHBondContact O-N 2.93Å; R350-T354 PolarHBondContact O-OG1 3Å; R350-T354 VanDerWaalsContact O-OG1 3.11Å; R350-T397 VanDerWaalsContact CZ-CB 3.44Å; R350-T397 PolarHBondContact NE-OG1 2.63Å; R350-T397 PolarHBondContact NH1-OG1 3.02Å; R350-N398 HydrophobicContact CB-CB 4.44Å; R350-N398 HydrophobicContact CG-CB 4.18Å; R350-D401 IonicContact CZ-OD2 3.95Å; R350-D401 VanDerWaalsContact CZ-OD2 3.24Å; R350-D401 IonicContact NE-OD2 3.08Å; R350-D401 PolarHBondContact NE-OD2 3.28Å; R350-D401 IonicContact NH2-OD1 3.73Å; R350-D401 PolarHBondContact NH2-OD1 3.2Å; R350-D401 IonicContact NH2-OD2 2.82Å; R350-D401 PolarHBondContact NH2-OD2 3.09Å; R350-A476 HydrophobicContact CG-CB 4.32Å
351	K	94.1	Very high	92.7	Very high	48 Å²	48	57.5 Å²	57.5	21%	0.209	28%	0.275	C	S	.	.	H	α-helix	trans	-61.9	-43.4	175.4	-73.9	-179.1	178.5	-168	0	111.4	V347 I348 S355 Y470 M471 A474	V347-K351 HydrophobicContact CG1-CD 4.19Å; V347-K351 HydrophobicContact CG1-CG 4.45Å; V347-K351 WeakPolarHBondContact O-CB 3.44Å; V347-K351 WeakPolarHBondContact O-CG 3.34Å; V347-K351 PolarHBondContact O-N 2.76Å; I348-K351 PolarHBondContact O-N 3.05Å; K351-S355 WeakPolarHBondContact O-CA 3.46Å; K351-S355 WeakPolarHBondContact O-CB 3.45Å; K351-S355 PolarHBondContact O-N 3.46Å; K351-Y470 HydrophobicContact CG-CE1 4.44Å; K351-M471 WeakPolarHBondContact CD-O 3.19Å; K351-M471 WeakPolarHBondContact CE-O 3.42Å; K351-M471 PolarHBondContact NZ-O 2.94Å; K351-A474 WeakPolarHBondContact CE-O 3.32Å; K351-A474 HydrophobicContact CG-CB 4.34Å; K351-A474 PolarHBondContact NZ-O 2.68Å
352	L	94	Very high	93	Very high	84 Å²	84	50 Å²	50	44%	0.44	24%	0.244	S	C	.	.	H	α-helix	trans	-61.9	-46	177.6	-178.2	64.6	0	0	0	111.9	I338 I348 L349 G356	I338-L352 HydrophobicContact CD1-CD2 4.22Å; I338-L352 HydrophobicContact CG2-CD2 4.36Å; I348-L352 WeakPolarHBondContact O-CB 3.32Å; I348-L352 PolarHBondContact O-N 3.19Å; L349-L352 PolarHBondContact O-N 2.9Å; L352-G356 WeakPolarHBondContact O-CA 3.47Å; L352-G356 PolarHBondContact O-N 2.83Å; L352-G356 VanDerWaalsContact O-N 3.07Å
353	M	93.3	Very high	93.4	Very high	11 Å²	11	46.5 Å²	46.5	5%	0.054	24%	0.237	C	C	.	.	H	α-helix	trans	-69.3	-49.6	-179.9	-64	-72	92.7	0	0	112.1	L334 A335 I338 L349 R350 G357 I390	L334-M353 HydrophobicContact CD2-CE 4.11Å; L334-M353 HydrophobicContact CD2-SD 4.32Å; L334-M353 HydrophobicContact CG-CE 4.41Å; A335-M353 HydrophobicContact CB-SD 4.46Å; I338-M353 HydrophobicContact CD1-CE 3.52Å; L349-M353 HydrophobicContact CD1-CG 4.28Å; L349-M353 VanDerWaalsContact O-CG 3.29Å; L349-M353 WeakPolarHBondContact O-CG 3.45Å; L349-M353 PolarHBondContact O-N 2.91Å; R350-M353 PolarHBondContact O-N 3.44Å; M353-G357 PolarHBondContact O-N 3.28Å; M353-G357 VanDerWaalsContact O-N 3.08Å; M353-I390 HydrophobicContact CB-CG2 4.39Å; M353-I390 HydrophobicContact CE-CG2 4.48Å; M353-I390 HydrophobicContact SD-CG2 3.98Å
354	T	94.6	Very high	93.8	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-72.6	-61.2	-177.4	-54	0	0	0	0	112.2	A283 R350 G357 L358 G394 F395 Y470	A283-T354 HydrophobicContact CB-CG2 3.82Å; R350-T354 WeakPolarHBondContact O-CB 3.33Å; R350-T354 PolarHBondContact O-N 2.93Å; R350-T354 PolarHBondContact O-OG1 3Å; R350-T354 VanDerWaalsContact O-OG1 3.11Å; T354-G357 PolarHBondContact O-N 3.2Å; T354-L358 HydrophobicContact CG2-CD1 4.1Å; T354-L358 WeakPolarHBondContact O-CG 3.47Å; T354-L358 PolarHBondContact O-N 3.02Å; T354-G394 VanDerWaalsContact OG1-CA 3.29Å; T354-G394 WeakPolarHBondContact OG1-CA 3.49Å; T354-F395 HydrophobicContact CG2-CB 3.98Å; T354-F395 HydrophobicContact CG2-CD1 4.17Å; T354-F395 PolarHBondContact OG1-N 2.92Å; T354-Y470 HydrophobicContact CG2-CD1 3.73Å; T354-Y470 HydrophobicContact CG2-CD2 4.07Å; T354-Y470 HydrophobicContact CG2-CE1 3.7Å; T354-Y470 HydrophobicContact CG2-CE2 4.04Å; T354-Y470 HydrophobicContact CG2-CG 3.9Å; T354-Y470 WeakPolarHBondContact OG1-CE1 2.93Å; T354-Y470 PolarHBondContact OG1-OH 2.88Å
355	S	95.9	Very high	94.2	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-69.6	-36.5	-176	-59.2	0	0	0	0	111.1	K351 L358 L359 A467 Y470 M471	K351-S355 WeakPolarHBondContact O-CA 3.46Å; K351-S355 WeakPolarHBondContact O-CB 3.45Å; K351-S355 PolarHBondContact O-N 3.46Å; S355-L358 PolarHBondContact O-N 3.14Å; S355-L359 WeakPolarHBondContact O-CB 3.38Å; S355-L359 VanDerWaalsContact O-CG 3.24Å; S355-L359 WeakPolarHBondContact O-CG 3.46Å; S355-L359 PolarHBondContact O-N 3.45Å; S355-A467 WeakPolarHBondContact CB-O 3.24Å; S355-A467 PolarHBondContact OG-O 2.89Å; S355-Y470 WeakPolarHBondContact OG-CD1 3.41Å; S355-M471 PolarHBondContact OG-N 3.35Å
356	G	95.7	Very high	94.6	Very high	24 Å²	24	33.4 Å²	33.4	25%	0.247	18%	0.184	C	C	.	.	H	α-helix	trans	-61.5	-46	172.7	0	0	0	0	0	111.9	L352 L358 L359 V360	L352-G356 WeakPolarHBondContact O-CA 3.47Å; L352-G356 PolarHBondContact O-N 2.83Å; L352-G356 VanDerWaalsContact O-N 3.07Å; G356-L358 PolarHBondContact O-N 3.22Å; G356-L359 PolarHBondContact O-N 2.81Å; G356-V360 WeakPolarHBondContact O-CG2 3.21Å; G356-V360 PolarHBondContact O-N 3.27Å
357	G	96.6	Very high	95	Very high	2 Å²	2	33.5 Å²	33.5	2%	0.021	19%	0.185	C	C	.	.	H	α-helix	trans	-61.9	-39.7	175.5	0	0	0	0	0	113.6	M353 T354 Q361	M353-G357 PolarHBondContact O-N 3.28Å; M353-G357 VanDerWaalsContact O-N 3.08Å; T354-G357 PolarHBondContact O-N 3.2Å; G357-Q361 WeakPolarHBondContact O-CB 3.2Å; G357-Q361 WeakPolarHBondContact O-CG 2.98Å; G357-Q361 PolarHBondContact O-N 3.19Å; G357-Q361 PolarHBondContact O-NE2 3.22Å; G357-Q361 VanDerWaalsContact O-NE2 3.1Å
358	L	97.5	Very high	95.2	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-70.7	-36.8	176.1	-73	170.7	0	0	0	112.9	A283 A286 E287 T354 S355 G356 Q361 A362 A391 F463 A467	A283-L358 HydrophobicContact CB-CD1 4.21Å; A286-L358 HydrophobicContact CB-CD2 4.45Å; E287-L358 HydrophobicContact CB-CD2 4.16Å; T354-L358 HydrophobicContact CG2-CD1 4.1Å; T354-L358 WeakPolarHBondContact O-CG 3.47Å; T354-L358 PolarHBondContact O-N 3.02Å; S355-L358 PolarHBondContact O-N 3.14Å; G356-L358 PolarHBondContact O-N 3.22Å; L358-Q361 WeakPolarHBondContact O-CB 3.45Å; L358-Q361 PolarHBondContact O-N 3.49Å; L358-A362 PolarHBondContact O-N 2.9Å; L358-A391 HydrophobicContact CD2-CB 4.39Å; L358-A391 HydrophobicContact CG-CB 4.11Å; L358-F463 HydrophobicContact CD2-CD1 3.75Å; L358-F463 HydrophobicContact CD2-CE1 4.24Å; L358-A467 HydrophobicContact CB-CB 3.72Å; L358-A467 HydrophobicContact CD1-CB 4.43Å
359	L	97.7	Very high	95.1	Very high	72 Å²	72	28.4 Å²	28.4	38%	0.377	16%	0.158	S	C	.	.	H	α-helix	trans	-69.4	-38.8	176.3	-73	172.5	0	0	0	112	S355 G356 Q361 A362 A363 A467	S355-L359 WeakPolarHBondContact O-CB 3.38Å; S355-L359 VanDerWaalsContact O-CG 3.24Å; S355-L359 WeakPolarHBondContact O-CG 3.46Å; S355-L359 PolarHBondContact O-N 3.45Å; G356-L359 PolarHBondContact O-N 2.81Å; L359-Q361 VanDerWaalsContact C-N 3.34Å; L359-A362 PolarHBondContact O-N 3.07Å; L359-A363 WeakPolarHBondContact O-CB 3.49Å; L359-A363 PolarHBondContact O-N 3.14Å; L359-A467 HydrophobicContact CD2-CB 3.85Å; L359-A467 HydrophobicContact CG-CB 3.76Å
360	V	97.6	Very high	95	Very high	38 Å²	38	32.2 Å²	32.2	23%	0.23	19%	0.185	C	C	.	.	H	α-helix	trans	-63.2	-43.8	172.6	175.1	0	0	0	0	110	G356 A362 A363 F364 V383 F387	G356-V360 WeakPolarHBondContact O-CG2 3.21Å; G356-V360 PolarHBondContact O-N 3.27Å; V360-A362 PolarHBondContact O-N 3.46Å; V360-A363 PolarHBondContact O-N 3.22Å; V360-F364 HydrophobicContact CG1-CD2 3.68Å; V360-F364 HydrophobicContact CG1-CE2 3.89Å; V360-F364 WeakPolarHBondContact O-CD2 3.06Å; V360-F364 PolarHBondContact O-N 2.91Å; V360-V383 HydrophobicContact CG1-CG1 4.29Å; V360-F387 HydrophobicContact CB-CB 4.24Å; V360-F387 HydrophobicContact CB-CD1 3.73Å; V360-F387 HydrophobicContact CB-CE1 4.23Å; V360-F387 HydrophobicContact CB-CG 3.98Å; V360-F387 HydrophobicContact CG1-CB 3.97Å; V360-F387 HydrophobicContact CG1-CD1 3.59Å; V360-F387 HydrophobicContact CG1-CD2 3.74Å; V360-F387 HydrophobicContact CG1-CE1 3.94Å; V360-F387 HydrophobicContact CG1-CE2 4.07Å; V360-F387 HydrophobicContact CG1-CG 3.48Å; V360-F387 VanDerWaalsContact CG1-CG 3.48Å; V360-F387 HydrophobicContact CG1-CZ 4.16Å; V360-F387 HydrophobicContact CG2-CD1 3.96Å; V360-F387 HydrophobicContact CG2-CE1 4.03Å
361	Q	97.9	Very high	94.9	Very high	4 Å²	4	31.3 Å²	31.3	2%	0.019	18%	0.183	C	C	.	.	H	α-helix	trans	-53.7	-50.5	171.4	-89.6	172.4	106.1	0	0	112.5	G357 L358 L359 A363 F364 V365 G384 F387 F463	G357-Q361 WeakPolarHBondContact O-CB 3.2Å; G357-Q361 WeakPolarHBondContact O-CG 2.98Å; G357-Q361 PolarHBondContact O-N 3.19Å; G357-Q361 PolarHBondContact O-NE2 3.22Å; G357-Q361 VanDerWaalsContact O-NE2 3.1Å; L358-Q361 WeakPolarHBondContact O-CB 3.45Å; L358-Q361 PolarHBondContact O-N 3.49Å; L359-Q361 VanDerWaalsContact C-N 3.34Å; Q361-A363 PolarHBondContact O-N 3.15Å; Q361-F364 PolarHBondContact O-N 3.19Å; Q361-V365 WeakPolarHBondContact O-CB 3.06Å; Q361-V365 WeakPolarHBondContact O-CG2 3.14Å; Q361-V365 PolarHBondContact O-N 3.18Å; Q361-G384 WeakPolarHBondContact CG-O 3.38Å; Q361-F387 HydrophobicContact CG-CB 4.41Å; Q361-F463 HydrophobicContact CB-CD1 4.38Å; Q361-F463 HydrophobicContact CB-CD2 3.79Å; Q361-F463 HydrophobicContact CB-CE1 4.33Å; Q361-F463 HydrophobicContact CB-CE2 3.72Å; Q361-F463 HydrophobicContact CB-CG 4.1Å; Q361-F463 HydrophobicContact CB-CZ 3.96Å; Q361-F463 HydrophobicContact CG-CE2 4.31Å; Q361-F463 HydrophobicContact CG-CZ 4.15Å
362	A	97.5	Very high	94.4	Very high	7 Å²	7	33.9 Å²	33.9	6%	0.058	21%	0.207	C	C	.	.	H	α-helix	trans	-58.7	-48	177.6	0	0	0	0	0	111.9	L358 L359 V360 F364 L366 T460 F463	L358-A362 PolarHBondContact O-N 2.9Å; L359-A362 PolarHBondContact O-N 3.07Å; V360-A362 PolarHBondContact O-N 3.46Å; A362-F364 PolarHBondContact O-N 2.99Å; A362-L366 VanDerWaalsContact O-CB 3.3Å; A362-L366 WeakPolarHBondContact O-CB 3.13Å; A362-L366 PolarHBondContact O-N 2.88Å; A362-T460 HydrophobicContact CB-CG2 4.1Å; A362-F463 HydrophobicContact CB-CB 3.77Å
363	A	97.5	Very high	94.2	Very high	47 Å²	47	33.9 Å²	33.9	39%	0.388	21%	0.208	S	C	.	.	H	α-helix	trans	-61.3	-46.4	-178.7	0	0	0	0	0	112	L359 V360 Q361 L366 L367	L359-A363 WeakPolarHBondContact O-CB 3.49Å; L359-A363 PolarHBondContact O-N 3.14Å; V360-A363 PolarHBondContact O-N 3.22Å; Q361-A363 PolarHBondContact O-N 3.15Å; A363-L366 WeakPolarHBondContact O-CB 3.36Å; A363-L366 PolarHBondContact O-N 3.07Å; A363-L367 VanDerWaalsContact O-CG 3.32Å; A363-L367 WeakPolarHBondContact O-CG 3.42Å; A363-L367 PolarHBondContact O-N 3.46Å
364	F	97.3	Very high	93.9	Very high	58 Å²	58	35 Å²	35	25%	0.254	22%	0.217	S	C	.	.	H	α-helix	trans	-76.7	-31.2	-177.2	-81.9	-91	0	0	0	113.5	V360 Q361 A362 L366 L367 T368 Y380 V383	V360-F364 HydrophobicContact CG1-CD2 3.68Å; V360-F364 HydrophobicContact CG1-CE2 3.89Å; V360-F364 WeakPolarHBondContact O-CD2 3.06Å; V360-F364 PolarHBondContact O-N 2.91Å; Q361-F364 PolarHBondContact O-N 3.19Å; A362-F364 PolarHBondContact O-N 2.99Å; F364-L366 VanDerWaalsContact C-N 3.31Å; F364-L367 HydrophobicContact CD1-CD1 4.14Å; F364-L367 HydrophobicContact CE1-CD1 4.29Å; F364-L367 HydrophobicContact CG-CD1 4.46Å; F364-L367 PolarHBondContact O-N 3.21Å; F364-T368 PolarHBondContact O-N 2.94Å; F364-T368 PolarHBondContact O-OG1 3.4Å; F364-Y380 AromaticContact CD1-CD1 3.83Å; F364-Y380 HydrophobicContact CD1-CD1 3.83Å; F364-Y380 HydrophobicContact CD1-CG 4.32Å; F364-Y380 HydrophobicContact CE1-CD1 4.04Å; F364-V383 HydrophobicContact CD1-CB 3.73Å; F364-V383 HydrophobicContact CD1-CG1 3.8Å; F364-V383 HydrophobicContact CD1-CG2 4.39Å; F364-V383 HydrophobicContact CD2-CB 4.45Å; F364-V383 HydrophobicContact CD2-CG1 3.7Å; F364-V383 HydrophobicContact CE1-CB 3.89Å; F364-V383 HydrophobicContact CE1-CG1 3.73Å; F364-V383 HydrophobicContact CE1-CG2 4.15Å; F364-V383 HydrophobicContact CE2-CG1 3.64Å; F364-V383 HydrophobicContact CG-CB 4.01Å; F364-V383 HydrophobicContact CG-CG1 3.76Å; F364-V383 HydrophobicContact CZ-CB 4.33Å; F364-V383 HydrophobicContact CZ-CG1 3.66Å
365	V	95.3	Very high	93.7	Very high	4 Å²	4	41.4 Å²	41.4	2%	0.024	25%	0.25	C	S	.	.	H	α-helix	trans	-64.8	-38.8	168.2	171.3	0	0	0	0	110.7	M294 Q361 T368 F456 T459 F463	M294-V365 HydrophobicContact CE-CG2 4.11Å; Q361-V365 WeakPolarHBondContact O-CB 3.06Å; Q361-V365 WeakPolarHBondContact O-CG2 3.14Å; Q361-V365 PolarHBondContact O-N 3.18Å; V365-T368 VanDerWaalsContact O-CB 3.29Å; V365-T368 WeakPolarHBondContact O-CB 3.23Å; V365-T368 PolarHBondContact O-N 3.46Å; V365-F456 HydrophobicContact CG1-CB 3.91Å; V365-F456 HydrophobicContact CG1-CD1 3.8Å; V365-F456 HydrophobicContact CG1-CG 4.21Å; V365-T459 HydrophobicContact CG1-CG2 4.31Å; V365-F463 HydrophobicContact CG2-CE2 3.97Å
366	L	95.3	Very high	93.6	Very high	80 Å²	80	45 Å²	45	42%	0.419	27%	0.269	S	S	.	.	H	α-helix	trans	-66.4	-39.1	174.3	-173	62.5	0	0	0	112.5	A362 A363 F364 T368 V369 Y457 T460	A362-L366 VanDerWaalsContact O-CB 3.3Å; A362-L366 WeakPolarHBondContact O-CB 3.13Å; A362-L366 PolarHBondContact O-N 2.88Å; A363-L366 WeakPolarHBondContact O-CB 3.36Å; A363-L366 PolarHBondContact O-N 3.07Å; F364-L366 VanDerWaalsContact C-N 3.31Å; L366-T368 PolarHBondContact O-N 3.32Å; L366-V369 WeakPolarHBondContact O-CB 3.37Å; L366-V369 PolarHBondContact O-N 3.08Å; L366-V369 VanDerWaalsContact O-N 3.12Å; L366-Y457 HydrophobicContact CD1-CD1 3.89Å; L366-Y457 HydrophobicContact CD1-CE1 3.64Å; L366-T460 HydrophobicContact CB-CG2 4.09Å
367	L	95.8	Very high	93.5	Very high	67 Å²	67	43.8 Å²	43.8	35%	0.351	26%	0.257	S	S	.	.	H	α-helix	trans	-64.5	-26	173.5	-71	173.2	0	0	0	112.8	A363 F364 V369 S370 Y380	A363-L367 VanDerWaalsContact O-CG 3.32Å; A363-L367 WeakPolarHBondContact O-CG 3.42Å; A363-L367 PolarHBondContact O-N 3.46Å; F364-L367 HydrophobicContact CD1-CD1 4.14Å; F364-L367 HydrophobicContact CE1-CD1 4.29Å; F364-L367 HydrophobicContact CG-CD1 4.46Å; F364-L367 PolarHBondContact O-N 3.21Å; L367-V369 PolarHBondContact O-N 3.07Å; L367-S370 PolarHBondContact O-N 3.1Å; L367-S370 PolarHBondContact O-OG 3.38Å; L367-Y380 HydrophobicContact CB-CD1 4.48Å; L367-Y380 HydrophobicContact CB-CD2 3.74Å; L367-Y380 HydrophobicContact CB-CE2 3.9Å; L367-Y380 HydrophobicContact CB-CG 4.05Å; L367-Y380 WeakPolarHBondContact O-CD2 3.42Å; L367-Y380 WeakPolarHBondContact O-CE2 2.89Å
368	T	92.8	Very high	93.3	Very high	2 Å²	2	44.3 Å²	44.3	1%	0.012	26%	0.259	C	S	.	.	H	α-helix	trans	-65.6	-29.6	174.8	-54.6	0	0	0	0	111.4	Y301 F364 V365 L366 A377 Y380 V381 F456	Y301-T368 HydrophobicContact CE1-CG2 4.17Å; Y301-T368 WeakPolarHBondContact OH-CG2 3.5Å; F364-T368 PolarHBondContact O-N 2.94Å; F364-T368 PolarHBondContact O-OG1 3.4Å; V365-T368 VanDerWaalsContact O-CB 3.29Å; V365-T368 WeakPolarHBondContact O-CB 3.23Å; V365-T368 PolarHBondContact O-N 3.46Å; L366-T368 PolarHBondContact O-N 3.32Å; T368-A377 HydrophobicContact CG2-CB 4.29Å; T368-Y380 WeakPolarHBondContact OG1-CB 3.46Å; T368-V381 HydrophobicContact CG2-CG2 3.86Å; T368-F456 HydrophobicContact CG2-CE2 4.15Å; T368-F456 HydrophobicContact CG2-CZ 4.16Å
369	V	90.1	Very high	93.2	Very high	8 Å²	8	46.4 Å²	46.4	5%	0.048	28%	0.277	C	S	.	.	H	α-helix	trans	-70.9	-31.4	177.6	167.5	0	0	0	0	112.8	L366 L367 R453 F456 Y457	L366-V369 WeakPolarHBondContact O-CB 3.37Å; L366-V369 PolarHBondContact O-N 3.08Å; L366-V369 VanDerWaalsContact O-N 3.12Å; L367-V369 PolarHBondContact O-N 3.07Å; V369-R453 HydrophobicContact CB-CG 4.38Å; V369-R453 HydrophobicContact CG1-CB 4.16Å; V369-R453 HydrophobicContact CG1-CG 3.63Å; V369-R453 HydrophobicContact CG2-CG 4.39Å; V369-R453 PolarHBondContact O-NE 2.86Å; V369-R453 PolarHBondContact O-NH2 2.88Å; V369-F456 HydrophobicContact CG2-CB 3.32Å; V369-F456 HydrophobicContact CG2-CD2 3.81Å; V369-F456 HydrophobicContact CG2-CG 3.97Å; V369-Y457 HydrophobicContact CG1-CE1 4Å; V369-Y457 HydrophobicContact CG1-CE2 4.35Å; V369-Y457 WeakPolarHBondContact CG1-OH 3.23Å
370	S	87.1	Confident	93.2	Very high	86 Å²	86	45.7 Å²	45.7	60%	0.601	27%	0.27	S	S	*	.	H	α-helix	trans	-88	-8.9	-172.9	63.3	0	0	0	0	114.3	L367	L367-S370 PolarHBondContact O-N 3.1Å; L367-S370 PolarHBondContact O-OG 3.38Å
371	T	88.9	Confident	93	Very high	16 Å²	16	44 Å²	44	10%	0.098	26%	0.259	C	S	.	.			trans	-109.5	139	-178.3	-173.4	0	0	0	0	112	N373 L376 A377 Y380	T371-N373 PolarHBondContact OG1-N 3.32Å; T371-L376 HydrophobicContact CG2-CB 4.41Å; T371-A377 HydrophobicContact CG2-CB 3.82Å; T371-Y380 HydrophobicContact CG2-CD2 3.84Å; T371-Y380 HydrophobicContact CG2-CE2 3.78Å
372	S	83.6	Confident	92.9	Very high	101 Å²	101	44.5 Å²	44.5	71%	0.706	26%	0.263	S	S	*	.			trans	-99.5	-4.8	168.6	-51.9	0	0	0	0	112.2
373	N	89.7	Confident	92.8	Very high	85 Å²	85	46.4 Å²	46.4	46%	0.455	27%	0.274	S	S	.	.			trans	-84.5	117.9	-178.6	-179	-43.2	0	0	0	109.9	T371 L375 L376 A377	T371-N373 PolarHBondContact OG1-N 3.32Å; N373-L375 VanDerWaalsContact C-N 3.29Å; N373-L375 PolarHBondContact O-N 3.4Å; N373-L375 WeakPolarHBondContact OD1-CB 3.48Å; N373-L375 PolarHBondContact OD1-N 2.8Å; N373-L376 HydrophobicContact CB-CB 4.16Å; N373-L376 HydrophobicContact CB-CD1 4.09Å; N373-L376 HydrophobicContact CB-CG 4.23Å; N373-L376 PolarHBondContact O-N 3.19Å; N373-L376 PolarHBondContact OD1-N 3.39Å; N373-A377 WeakPolarHBondContact O-CB 3.4Å; N373-A377 PolarHBondContact O-N 3.38Å
374	S	88.7	Confident	92.7	Very high	35 Å²	35	44.2 Å²	44.2	25%	0.245	26%	0.256	C	S	.	.	H	α-helix	trans	-56.7	-37.4	-178.1	-52	0	0	0	0	114	L306 T378	L306-S374 PolarHBondContact O-OG 2.7Å; S374-T378 VanDerWaalsContact O-CB 3.3Å; S374-T378 WeakPolarHBondContact O-CB 3.38Å; S374-T378 PolarHBondContact O-N 3.47Å; S374-T378 PolarHBondContact O-OG1 3.02Å
375	L	89.8	Confident	92.6	Very high	133 Å²	133	42 Å²	42	70%	0.696	25%	0.247	S	C	*	.	H	α-helix	trans	-69.1	-45	178.6	-177.4	65.2	0	0	0	111.2	N373 T378 A379	N373-L375 VanDerWaalsContact C-N 3.29Å; N373-L375 PolarHBondContact O-N 3.4Å; N373-L375 WeakPolarHBondContact OD1-CB 3.48Å; N373-L375 PolarHBondContact OD1-N 2.8Å; L375-T378 PolarHBondContact O-N 2.91Å; L375-A379 WeakPolarHBondContact O-CB 3.35Å; L375-A379 PolarHBondContact O-N 3.05Å
376	L	93.7	Very high	92.6	Very high	75 Å²	75	41.8 Å²	41.8	39%	0.393	25%	0.246	S	C	.	.	H	α-helix	trans	-66.4	-43.7	177.5	-70.2	178.1	0	0	0	111.6	T371 N373 T378 A379 Y380	T371-L376 HydrophobicContact CG2-CB 4.41Å; N373-L376 HydrophobicContact CB-CB 4.16Å; N373-L376 HydrophobicContact CB-CD1 4.09Å; N373-L376 HydrophobicContact CB-CG 4.23Å; N373-L376 PolarHBondContact O-N 3.19Å; N373-L376 PolarHBondContact OD1-N 3.39Å; L376-T378 VanDerWaalsContact C-N 3.3Å; L376-T378 PolarHBondContact O-N 3.49Å; L376-A379 PolarHBondContact O-N 3.27Å; L376-Y380 HydrophobicContact CB-CE2 4.23Å; L376-Y380 VanDerWaalsContact O-CD2 3.32Å; L376-Y380 WeakPolarHBondContact O-CD2 3.45Å; L376-Y380 PolarHBondContact O-N 2.83Å
377	A	93.3	Very high	92.6	Very high	0 Å²	0	41 Å²	41	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-57.2	-46	175.1	0	0	0	0	0	111	L306 T368 T371 N373 A379 Y380 V381	L306-A377 HydrophobicContact CD1-CB 3.73Å; L306-A377 HydrophobicContact CD2-CB 3.79Å; L306-A377 HydrophobicContact CG-CB 4.43Å; T368-A377 HydrophobicContact CG2-CB 4.29Å; T371-A377 HydrophobicContact CG2-CB 3.82Å; N373-A377 WeakPolarHBondContact O-CB 3.4Å; N373-A377 PolarHBondContact O-N 3.38Å; A377-A379 PolarHBondContact O-N 2.85Å; A377-Y380 PolarHBondContact O-N 3.2Å; A377-V381 WeakPolarHBondContact O-CG2 3.36Å; A377-V381 PolarHBondContact O-N 3.43Å
378	T	92.8	Very high	92.5	Very high	12 Å²	12	37.8 Å²	37.8	7%	0.074	22%	0.222	C	C	.	.	H	α-helix	trans	-61.2	-45.4	176.1	-58.6	0	0	0	0	111.8	M302 V316 S374 L375 L376 Y380 V381 C382	M302-T378 HydrophobicContact CE-CG2 4.33Å; V316-T378 HydrophobicContact CG1-CG2 3.41Å; V316-T378 VanDerWaalsContact CG1-CG2 3.41Å; S374-T378 VanDerWaalsContact O-CB 3.3Å; S374-T378 WeakPolarHBondContact O-CB 3.38Å; S374-T378 PolarHBondContact O-N 3.47Å; S374-T378 PolarHBondContact O-OG1 3.02Å; L375-T378 PolarHBondContact O-N 2.91Å; L376-T378 VanDerWaalsContact C-N 3.3Å; L376-T378 PolarHBondContact O-N 3.49Å; T378-Y380 VanDerWaalsContact C-N 3.33Å; T378-Y380 PolarHBondContact O-N 2.64Å; T378-V381 PolarHBondContact O-N 2.89Å; T378-C382 WeakPolarHBondContact O-CB 3.45Å; T378-C382 PolarHBondContact O-N 3.04Å; T378-C382 PolarHBondContact O-SG 2.89Å
379	A	95.4	Very high	92.4	Very high	45 Å²	45	37.7 Å²	37.7	37%	0.372	22%	0.222	S	C	.	.	H	α-helix	trans	-60.9	-42.6	177.4	0	0	0	0	0	111.6	L375 L376 A377 C382 V383	L375-A379 WeakPolarHBondContact O-CB 3.35Å; L375-A379 PolarHBondContact O-N 3.05Å; L376-A379 PolarHBondContact O-N 3.27Å; A377-A379 PolarHBondContact O-N 2.85Å; A379-C382 WeakPolarHBondContact O-CB 3.39Å; A379-C382 PolarHBondContact O-N 3.46Å; A379-V383 WeakPolarHBondContact O-CG2 3.48Å; A379-V383 PolarHBondContact O-N 3.08Å
380	Y	96.4	Very high	92.6	Very high	56 Å²	56	37.9 Å²	37.9	22%	0.22	22%	0.222	C	C	.	.	H	α-helix	trans	-64.8	-44	177.3	-61.3	-26.4	0	0	0	112.3	F364 L367 T368 T371 L376 A377 T378 C382 V383 G384	F364-Y380 AromaticContact CD1-CD1 3.83Å; F364-Y380 HydrophobicContact CD1-CD1 3.83Å; F364-Y380 HydrophobicContact CD1-CG 4.32Å; F364-Y380 HydrophobicContact CE1-CD1 4.04Å; L367-Y380 HydrophobicContact CB-CD1 4.48Å; L367-Y380 HydrophobicContact CB-CD2 3.74Å; L367-Y380 HydrophobicContact CB-CE2 3.9Å; L367-Y380 HydrophobicContact CB-CG 4.05Å; L367-Y380 WeakPolarHBondContact O-CD2 3.42Å; L367-Y380 WeakPolarHBondContact O-CE2 2.89Å; T368-Y380 WeakPolarHBondContact OG1-CB 3.46Å; T371-Y380 HydrophobicContact CG2-CD2 3.84Å; T371-Y380 HydrophobicContact CG2-CE2 3.78Å; L376-Y380 HydrophobicContact CB-CE2 4.23Å; L376-Y380 VanDerWaalsContact O-CD2 3.32Å; L376-Y380 WeakPolarHBondContact O-CD2 3.45Å; L376-Y380 PolarHBondContact O-N 2.83Å; A377-Y380 PolarHBondContact O-N 3.2Å; T378-Y380 VanDerWaalsContact C-N 3.33Å; T378-Y380 PolarHBondContact O-N 2.64Å; Y380-C382 VanDerWaalsContact C-N 3.31Å; Y380-C382 PolarHBondContact O-N 3.35Å; Y380-V383 PolarHBondContact O-N 2.8Å; Y380-G384 PolarHBondContact O-N 3.04Å
381	V	94.5	Very high	92.9	Very high	2 Å²	2	33.8 Å²	33.8	1%	0.012	19%	0.194	C	C	.	.	H	α-helix	trans	-61.7	-40.2	174.3	173.2	0	0	0	0	111.4	L298 P320 T368 A377 T378 V383 G384 V385	L298-V381 HydrophobicContact CD1-CG1 3.75Å; L298-V381 HydrophobicContact CD2-CG1 4.22Å; P320-V381 HydrophobicContact CB-CG1 4.32Å; P320-V381 HydrophobicContact CG-CG1 4Å; T368-V381 HydrophobicContact CG2-CG2 3.86Å; A377-V381 WeakPolarHBondContact O-CG2 3.36Å; A377-V381 PolarHBondContact O-N 3.43Å; T378-V381 PolarHBondContact O-N 2.89Å; V381-V383 PolarHBondContact O-N 3.04Å; V381-G384 PolarHBondContact O-N 2.94Å; V381-V385 HydrophobicContact CG1-CG2 3.98Å; V381-V385 WeakPolarHBondContact O-CB 3.45Å; V381-V385 WeakPolarHBondContact O-CG2 3.4Å; V381-V385 PolarHBondContact O-N 3.34Å
382	C	95.3	Very high	92.9	Very high	15 Å²	15	35.7 Å²	35.7	10%	0.101	20%	0.199	C	C	.	.	H	α-helix	trans	-59.9	-46.1	176.6	-70	0	0	0	0	111.8	T378 A379 Y380 G386	T378-C382 WeakPolarHBondContact O-CB 3.45Å; T378-C382 PolarHBondContact O-N 3.04Å; T378-C382 PolarHBondContact O-SG 2.89Å; A379-C382 WeakPolarHBondContact O-CB 3.39Å; A379-C382 PolarHBondContact O-N 3.46Å; Y380-C382 VanDerWaalsContact C-N 3.31Å; Y380-C382 PolarHBondContact O-N 3.35Å; C382-G386 WeakPolarHBondContact O-CA 3.26Å; C382-G386 PolarHBondContact O-N 3.43Å
383	V	96.2	Very high	93.1	Very high	48 Å²	48	31.8 Å²	31.8	29%	0.291	17%	0.172	S	C	.	.	H	α-helix	trans	-67.3	-44.8	177.2	177.8	0	0	0	0	110.7	V360 F364 A379 Y380 V381 G386 F387	V360-V383 HydrophobicContact CG1-CG1 4.29Å; F364-V383 HydrophobicContact CD1-CB 3.73Å; F364-V383 HydrophobicContact CD1-CG1 3.8Å; F364-V383 HydrophobicContact CD1-CG2 4.39Å; F364-V383 HydrophobicContact CD2-CB 4.45Å; F364-V383 HydrophobicContact CD2-CG1 3.7Å; F364-V383 HydrophobicContact CE1-CB 3.89Å; F364-V383 HydrophobicContact CE1-CG1 3.73Å; F364-V383 HydrophobicContact CE1-CG2 4.15Å; F364-V383 HydrophobicContact CE2-CG1 3.64Å; F364-V383 HydrophobicContact CG-CB 4.01Å; F364-V383 HydrophobicContact CG-CG1 3.76Å; F364-V383 HydrophobicContact CZ-CB 4.33Å; F364-V383 HydrophobicContact CZ-CG1 3.66Å; A379-V383 WeakPolarHBondContact O-CG2 3.48Å; A379-V383 PolarHBondContact O-N 3.08Å; Y380-V383 PolarHBondContact O-N 2.8Å; V381-V383 PolarHBondContact O-N 3.04Å; V383-G386 PolarHBondContact O-N 3.29Å; V383-F387 HydrophobicContact CG1-CD2 3.87Å; V383-F387 HydrophobicContact CG1-CE2 3.92Å; V383-F387 VanDerWaalsContact O-CD2 3.32Å; V383-F387 WeakPolarHBondContact O-CD2 3.34Å; V383-F387 PolarHBondContact O-N 3.27Å
384	G	95.7	Very high	93	Very high	1 Å²	1	27.8 Å²	27.8	1%	0.01	15%	0.151	C	C	.	.	H	α-helix	trans	-55.7	-67.2	177.6	0	0	0	0	0	111.5	Q361 Y380 V381 G386 F387	Q361-G384 WeakPolarHBondContact CG-O 3.38Å; Y380-G384 PolarHBondContact O-N 3.04Å; V381-G384 PolarHBondContact O-N 2.94Å; G384-G386 PolarHBondContact O-N 3.36Å; G384-F387 PolarHBondContact O-N 3.1Å
385	V	94.4	Very high	92.9	Very high	10 Å²	10	26.2 Å²	26.2	6%	0.061	14%	0.14	C	C	.	.	H	α-helix	trans	-57.9	-36.9	179.6	177.5	0	0	0	0	111.4	M294 P320 Y321 M324 V381 F387 G388	M294-V385 HydrophobicContact CB-CG2 4.21Å; M294-V385 HydrophobicContact CG-CG2 3.97Å; P320-V385 HydrophobicContact CB-CB 3.76Å; P320-V385 HydrophobicContact CB-CG1 3.94Å; P320-V385 HydrophobicContact CB-CG2 4.09Å; Y321-V385 HydrophobicContact CD1-CG1 3.98Å; Y321-V385 HydrophobicContact CE1-CG1 4.01Å; M324-V385 HydrophobicContact CB-CG1 4.33Å; M324-V385 WeakPolarHBondContact CG-O 3.4Å; M324-V385 HydrophobicContact SD-CG1 4.37Å; V381-V385 HydrophobicContact CG1-CG2 3.98Å; V381-V385 WeakPolarHBondContact O-CB 3.45Å; V381-V385 WeakPolarHBondContact O-CG2 3.4Å; V381-V385 PolarHBondContact O-N 3.34Å; V385-F387 PolarHBondContact O-N 3.18Å; V385-G388 WeakPolarHBondContact O-CA 3.28Å; V385-G388 PolarHBondContact O-N 3.5Å; V385-G388 VanDerWaalsContact O-N 3.07Å
386	G	94.7	Very high	92.6	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-55.9	-50	177	0	0	0	0	0	113.5	L327 C382 V383 G384 G388 G389	L327-G386 WeakPolarHBondContact CB-O 3.34Å; L327-G386 WeakPolarHBondContact CD1-O 3.22Å; C382-G386 WeakPolarHBondContact O-CA 3.26Å; C382-G386 PolarHBondContact O-N 3.43Å; V383-G386 PolarHBondContact O-N 3.29Å; G384-G386 PolarHBondContact O-N 3.36Å; G386-G388 PolarHBondContact O-N 2.96Å; G386-G388 VanDerWaalsContact O-N 3.15Å; G386-G389 PolarHBondContact O-N 2.77Å
387	F	95.8	Very high	92	Very high	63 Å²	63	19.1 Å²	19.1	28%	0.276	11%	0.106	S	C	.	.	H	α-helix	trans	-66.6	-13.3	179.1	-89.8	-106.7	0	0	0	113.4	L327 V360 Q361 V383 G384 V385 G389 I390 A391	L327-F387 HydrophobicContact CD1-CD2 4.03Å; L327-F387 HydrophobicContact CD1-CE2 4.36Å; V360-F387 HydrophobicContact CB-CB 4.24Å; V360-F387 HydrophobicContact CB-CD1 3.73Å; V360-F387 HydrophobicContact CB-CE1 4.23Å; V360-F387 HydrophobicContact CB-CG 3.98Å; V360-F387 HydrophobicContact CG1-CB 3.97Å; V360-F387 HydrophobicContact CG1-CD1 3.59Å; V360-F387 HydrophobicContact CG1-CD2 3.74Å; V360-F387 HydrophobicContact CG1-CE1 3.94Å; V360-F387 HydrophobicContact CG1-CE2 4.07Å; V360-F387 HydrophobicContact CG1-CG 3.48Å; V360-F387 VanDerWaalsContact CG1-CG 3.48Å; V360-F387 HydrophobicContact CG1-CZ 4.16Å; V360-F387 HydrophobicContact CG2-CD1 3.96Å; V360-F387 HydrophobicContact CG2-CE1 4.03Å; Q361-F387 HydrophobicContact CG-CB 4.41Å; V383-F387 HydrophobicContact CG1-CD2 3.87Å; V383-F387 HydrophobicContact CG1-CE2 3.92Å; V383-F387 VanDerWaalsContact O-CD2 3.32Å; V383-F387 WeakPolarHBondContact O-CD2 3.34Å; V383-F387 PolarHBondContact O-N 3.27Å; G384-F387 PolarHBondContact O-N 3.1Å; V385-F387 PolarHBondContact O-N 3.18Å; F387-G389 PolarHBondContact O-N 3.18Å; F387-I390 HydrophobicContact CD1-CD1 3.8Å; F387-I390 HydrophobicContact CE1-CD1 3.84Å; F387-I390 HydrophobicContact CG-CD1 4.38Å; F387-I390 HydrophobicContact CZ-CD1 4.45Å; F387-I390 PolarHBondContact O-N 2.83Å; F387-I390 VanDerWaalsContact O-N 3.1Å; F387-A391 PolarHBondContact O-N 3.49Å
388	G	93.3	Very high	91.5	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-52.5	-36.4	164.5	0	0	0	0	0	112.8	V385 G386 I390 A391 W392	V385-G388 WeakPolarHBondContact O-CA 3.28Å; V385-G388 PolarHBondContact O-N 3.5Å; V385-G388 VanDerWaalsContact O-N 3.07Å; G386-G388 PolarHBondContact O-N 2.96Å; G386-G388 VanDerWaalsContact O-N 3.15Å; G388-I390 PolarHBondContact O-N 3.41Å; G388-A391 PolarHBondContact O-N 3Å; G388-W392 VanDerWaalsContact O-CB 3.28Å; G388-W392 WeakPolarHBondContact O-CB 3.47Å; G388-W392 PolarHBondContact O-N 3.19Å
389	G	91.2	Very high	90.6	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-62.7	-38.3	176.1	0	0	0	0	0	113.4	L328 G386 F387 S393	L328-G389 VanDerWaalsContact CD1-O 3.31Å; L328-G389 WeakPolarHBondContact CD1-O 3.48Å; G386-G389 PolarHBondContact O-N 2.77Å; F387-G389 PolarHBondContact O-N 3.18Å; G389-S393 WeakPolarHBondContact O-CB 3.47Å; G389-S393 PolarHBondContact O-N 2.89Å; G389-S393 VanDerWaalsContact O-N 3.11Å
390	I	93.7	Very high	89.5	Confident	12 Å²	12	20.6 Å²	20.6	6%	0.062	11%	0.107	C	C	.	.	H	α-helix	trans	-71.1	-44.7	176.5	-60.5	175.1	0	0	0	110.2	L327 L334 M353 F387 G388 W392 S393 G394	L327-I390 HydrophobicContact CB-CG1 4.32Å; L334-I390 HydrophobicContact CD2-CD1 4.44Å; M353-I390 HydrophobicContact CB-CG2 4.39Å; M353-I390 HydrophobicContact CE-CG2 4.48Å; M353-I390 HydrophobicContact SD-CG2 3.98Å; F387-I390 HydrophobicContact CD1-CD1 3.8Å; F387-I390 HydrophobicContact CE1-CD1 3.84Å; F387-I390 HydrophobicContact CG-CD1 4.38Å; F387-I390 HydrophobicContact CZ-CD1 4.45Å; F387-I390 PolarHBondContact O-N 2.83Å; F387-I390 VanDerWaalsContact O-N 3.1Å; G388-I390 PolarHBondContact O-N 3.41Å; I390-W392 VanDerWaalsContact C-N 3.35Å; I390-W392 PolarHBondContact O-N 3.47Å; I390-S393 PolarHBondContact O-N 3.2Å; I390-G394 PolarHBondContact O-N 3.29Å
391	A	93.9	Very high	88.5	Confident	0 Å²	0	19.4 Å²	19.4	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-59.6	-46.9	177.7	0	0	0	0	0	111.4	E287 L358 F387 G388 S393 G394 F395	E287-A391 HydrophobicContact CG-CB 4.47Å; L358-A391 HydrophobicContact CD2-CB 4.39Å; L358-A391 HydrophobicContact CG-CB 4.11Å; F387-A391 PolarHBondContact O-N 3.49Å; G388-A391 PolarHBondContact O-N 3Å; A391-S393 PolarHBondContact O-N 3.34Å; A391-G394 PolarHBondContact O-N 3.43Å; A391-G394 VanDerWaalsContact O-N 3.08Å; A391-F395 WeakPolarHBondContact O-CD1 3.33Å; A391-F395 PolarHBondContact O-N 3.28Å
392	W	89.5	Confident	87.4	Confident	56 Å²	56	19.3 Å²	19.3	21%	0.212	10%	0.103	C	C	.	.	H	α-helix	trans	-54.3	-52	175.3	-170.9	-68.4	0	0	0	111.7	E287 M324 L328 G388 I390 G394 F395 S396	E287-W392 WeakPolarHBondContact OE2-CZ3 3.27Å; M324-W392 HydrophobicContact CE-CE3 4.46Å; L328-W392 HydrophobicContact CD1-CB 4.38Å; L328-W392 HydrophobicContact CD1-CG 4.47Å; G388-W392 VanDerWaalsContact O-CB 3.28Å; G388-W392 WeakPolarHBondContact O-CB 3.47Å; G388-W392 PolarHBondContact O-N 3.19Å; I390-W392 VanDerWaalsContact C-N 3.35Å; I390-W392 PolarHBondContact O-N 3.47Å; W392-G394 PolarHBondContact O-N 3.04Å; W392-F395 HydrophobicContact CB-CE1 4.3Å; W392-F395 HydrophobicContact CB-CZ 4.32Å; W392-F395 HydrophobicContact CD2-CZ 4.03Å; W392-F395 HydrophobicContact CE3-CZ 4.15Å; W392-F395 HydrophobicContact CG-CZ 4.14Å; W392-S396 WeakPolarHBondContact O-CB 3.47Å; W392-S396 PolarHBondContact O-N 2.87Å; W392-S396 PolarHBondContact O-OG 3.06Å
393	S	86.8	Confident	85.9	Confident	19 Å²	19	18.7 Å²	18.7	13%	0.133	10%	0.099	C	C	.	.	H	α-helix	trans	-58.4	-33.9	177.7	-177.4	0	0	0	0	112.8	S331 G389 I390 A391 S396 T397	S331-S393 WeakPolarHBondContact OG-CB 3.36Å; S331-S393 PolarHBondContact OG-OG 2.61Å; G389-S393 WeakPolarHBondContact O-CB 3.47Å; G389-S393 PolarHBondContact O-N 2.89Å; G389-S393 VanDerWaalsContact O-N 3.11Å; I390-S393 PolarHBondContact O-N 3.2Å; A391-S393 PolarHBondContact O-N 3.34Å; S393-S396 PolarHBondContact O-OG 3.23Å; S393-T397 WeakPolarHBondContact O-CB 3.38Å; S393-T397 WeakPolarHBondContact O-CG2 3.46Å; S393-T397 PolarHBondContact O-N 3.13Å; S393-T397 PolarHBondContact O-OG1 2.86Å
394	G	87.6	Confident	83.9	Confident	1 Å²	1	18.2 Å²	18.2	1%	0.01	10%	0.095	C	C	.	.	H	α-helix	trans	-67.8	-57.2	179.9	0	0	0	0	0	113.1	T354 I390 A391 W392 T397 N398	T354-G394 VanDerWaalsContact OG1-CA 3.29Å; T354-G394 WeakPolarHBondContact OG1-CA 3.49Å; I390-G394 PolarHBondContact O-N 3.29Å; A391-G394 PolarHBondContact O-N 3.43Å; A391-G394 VanDerWaalsContact O-N 3.08Å; W392-G394 PolarHBondContact O-N 3.04Å; G394-T397 PolarHBondContact O-OG1 3.4Å; G394-N398 PolarHBondContact O-N 2.86Å
395	F	87.2	Confident	81.4	Confident	2 Å²	2	22.7 Å²	22.7	1%	0.009	12%	0.115	C	C	.	.	H	α-helix	trans	-75.9	-32.4	-176.9	69.2	-105.4	0	0	0	112.3	A283 H284 E287 T354 A391 W392 T397 N398 Q399 Y470	A283-F395 HydrophobicContact CB-CB 4.38Å; H284-F395 HydrophobicContact CB-CD2 4.07Å; H284-F395 HydrophobicContact CB-CE2 3.79Å; H284-F395 HydrophobicContact CB-CZ 4.13Å; H284-F395 AromaticContact CD2-CE2 3.46Å; H284-F395 VanDerWaalsContact CD2-CE2 3.46Å; H284-F395 WeakPolarHBondContact CD2-CE2 3.41Å; H284-F395 AromaticContact CD2-CZ 3.46Å; H284-F395 VanDerWaalsContact CD2-CZ 3.46Å; H284-F395 WeakPolarHBondContact CD2-CZ 3.15Å; H284-F395 AromaticContact CG-CE2 3.55Å; H284-F395 AromaticContact CG-CZ 3.92Å; E287-F395 HydrophobicContact CB-CE1 3.91Å; E287-F395 HydrophobicContact CB-CZ 4.46Å; E287-F395 HydrophobicContact CG-CE1 4.06Å; T354-F395 HydrophobicContact CG2-CB 3.98Å; T354-F395 HydrophobicContact CG2-CD1 4.17Å; T354-F395 PolarHBondContact OG1-N 2.92Å; A391-F395 WeakPolarHBondContact O-CD1 3.33Å; A391-F395 PolarHBondContact O-N 3.28Å; W392-F395 HydrophobicContact CB-CE1 4.3Å; W392-F395 HydrophobicContact CB-CZ 4.32Å; W392-F395 HydrophobicContact CD2-CZ 4.03Å; W392-F395 HydrophobicContact CE3-CZ 4.15Å; W392-F395 HydrophobicContact CG-CZ 4.14Å; F395-T397 PolarHBondContact O-N 2.72Å; F395-N398 PolarHBondContact O-N 3.26Å; F395-N398 VanDerWaalsContact O-N 3.15Å; F395-Q399 PolarHBondContact O-N 2.93Å; F395-Q399 VanDerWaalsContact O-N 3.14Å; F395-Y470 HydrophobicContact CB-CE2 4.09Å
396	S	82.6	Confident	78.6	Confident	24 Å²	24	24.8 Å²	24.8	17%	0.168	13%	0.134	C	C	.	.	H	α-helix	trans	-68.9	-20.2	179.5	65.7	0	0	0	0	113.1	W392 S393 Q399	W392-S396 WeakPolarHBondContact O-CB 3.47Å; W392-S396 PolarHBondContact O-N 2.87Å; W392-S396 PolarHBondContact O-OG 3.06Å; S393-S396 PolarHBondContact O-OG 3.23Å; S396-Q399 VanDerWaalsContact CA-NE2 3.31Å; S396-Q399 VanDerWaalsContact O-CG 3.24Å; S396-Q399 WeakPolarHBondContact O-CG 3.44Å; S396-Q399 PolarHBondContact O-NE2 2.96Å
397	T	81.4	Confident	75.9	Confident	35 Å²	35	26.1 Å²	26.1	22%	0.215	14%	0.143	C	C	.	.	H	α-helix	trans	-91.1	-32.3	170.3	50.7	0	0	0	0	111.4	R350 S393 G394 F395 Q399 L400 D401	R350-T397 VanDerWaalsContact CZ-CB 3.44Å; R350-T397 PolarHBondContact NE-OG1 2.63Å; R350-T397 PolarHBondContact NH1-OG1 3.02Å; S393-T397 WeakPolarHBondContact O-CB 3.38Å; S393-T397 WeakPolarHBondContact O-CG2 3.46Å; S393-T397 PolarHBondContact O-N 3.13Å; S393-T397 PolarHBondContact O-OG1 2.86Å; G394-T397 PolarHBondContact O-OG1 3.4Å; F395-T397 PolarHBondContact O-N 2.72Å; T397-Q399 VanDerWaalsContact C-N 3.29Å; T397-Q399 PolarHBondContact O-N 3.01Å; T397-L400 WeakPolarHBondContact O-CB 3.28Å; T397-L400 PolarHBondContact O-N 3.2Å; T397-D401 PolarHBondContact O-N 3.48Å
398	N	83.9	Confident	73	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-61	-34.8	176.6	-167.4	24.2	0	0	0	113.3	I280 R350 G394 F395 L400 D401 V402 Y470 Q475	I280-N398 HydrophobicContact CD1-CB 4.3Å; I280-N398 HydrophobicContact CG1-CB 4.43Å; R350-N398 HydrophobicContact CB-CB 4.44Å; R350-N398 HydrophobicContact CG-CB 4.18Å; G394-N398 PolarHBondContact O-N 2.86Å; F395-N398 PolarHBondContact O-N 3.26Å; F395-N398 VanDerWaalsContact O-N 3.15Å; N398-L400 PolarHBondContact O-N 3.36Å; N398-D401 PolarHBondContact O-N 3.28Å; N398-D401 VanDerWaalsContact O-N 3.11Å; N398-V402 WeakPolarHBondContact O-CG2 3.16Å; N398-V402 PolarHBondContact O-N 3.33Å; N398-Y470 WeakPolarHBondContact CB-OH 3.42Å; N398-Y470 PolarHBondContact ND2-OH 3.06Å; N398-Q475 PolarHBondContact ND2-O 3.26Å; N398-Q475 PolarHBondContact OD1-O 2.9Å
399	Q	74	Confident	70.3	Confident	12 Å²	12	39.1 Å²	39.1	6%	0.056	21%	0.214	C	C	.	.	H	α-helix	trans	-60.9	-29	174.3	71.7	-167.4	-30.1	0	0	113.5	I280 F395 S396 T397 A403 V421 M422	I280-Q399 HydrophobicContact CD1-CB 4.37Å; I280-Q399 HydrophobicContact CG2-CB 4.35Å; F395-Q399 PolarHBondContact O-N 2.93Å; F395-Q399 VanDerWaalsContact O-N 3.14Å; S396-Q399 VanDerWaalsContact CA-NE2 3.31Å; S396-Q399 VanDerWaalsContact O-CG 3.24Å; S396-Q399 WeakPolarHBondContact O-CG 3.44Å; S396-Q399 PolarHBondContact O-NE2 2.96Å; T397-Q399 VanDerWaalsContact C-N 3.29Å; T397-Q399 PolarHBondContact O-N 3.01Å; Q399-A403 VanDerWaalsContact O-CB 3.29Å; Q399-A403 WeakPolarHBondContact O-CB 3.09Å; Q399-A403 PolarHBondContact O-N 3.35Å; Q399-V421 HydrophobicContact CB-CG1 4.21Å; Q399-M422 VanDerWaalsContact OE1-CB 3.3Å; Q399-M422 PolarHBondContact OE1-SD 3.29Å
400	L	71.7	Confident	67.7	Low	77 Å²	77	48.3 Å²	48.3	40%	0.403	25%	0.254	S	S	.	.	H	α-helix	trans	-73.2	-46.9	173.7	-58.4	171.9	0	0	0	108.9	T397 N398 V402 A403 D404 P415 A418	T397-L400 WeakPolarHBondContact O-CB 3.28Å; T397-L400 PolarHBondContact O-N 3.2Å; N398-L400 PolarHBondContact O-N 3.36Å; L400-V402 VanDerWaalsContact C-N 3.34Å; L400-V402 PolarHBondContact O-N 2.95Å; L400-A403 PolarHBondContact O-N 3.33Å; L400-A403 VanDerWaalsContact O-N 3.15Å; L400-D404 WeakPolarHBondContact O-CB 3.32Å; L400-D404 PolarHBondContact O-N 2.98Å; L400-P415 HydrophobicContact CD2-CG 4.22Å; L400-A418 HydrophobicContact CD2-CB 3.91Å
401	D	75.1	Confident	64.8	Low	31 Å²	31	53 Å²	53	17%	0.166	27%	0.274	C	S	.	.	H	α-helix	trans	-59.6	-41.9	-178.3	-58.6	-31.1	0	0	0	112.7	L346 R350 T397 N398 A403 A476	L346-D401 HydrophobicContact CD2-CB 4.28Å; R350-D401 IonicContact CZ-OD2 3.95Å; R350-D401 VanDerWaalsContact CZ-OD2 3.24Å; R350-D401 IonicContact NE-OD2 3.08Å; R350-D401 PolarHBondContact NE-OD2 3.28Å; R350-D401 IonicContact NH2-OD1 3.73Å; R350-D401 PolarHBondContact NH2-OD1 3.2Å; R350-D401 IonicContact NH2-OD2 2.82Å; R350-D401 PolarHBondContact NH2-OD2 3.09Å; T397-D401 PolarHBondContact O-N 3.48Å; N398-D401 PolarHBondContact O-N 3.28Å; N398-D401 VanDerWaalsContact O-N 3.11Å; D401-A403 VanDerWaalsContact C-N 3.33Å; D401-A403 PolarHBondContact O-N 3.47Å; D401-A476 HydrophobicContact CB-CB 4.08Å
402	V	70.9	Confident	62.1	Low	0 Å²	0	58 Å²	58	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-68.1	-32.1	179.1	171.3	0	0	0	0	112.3	V277 I280 N398 L400 Q475 Q479 W481	V277-V402 HydrophobicContact CG2-CG1 4.39Å; I280-V402 HydrophobicContact CD1-CB 4.36Å; I280-V402 HydrophobicContact CD1-CG2 3.88Å; N398-V402 WeakPolarHBondContact O-CG2 3.16Å; N398-V402 PolarHBondContact O-N 3.33Å; L400-V402 VanDerWaalsContact C-N 3.34Å; L400-V402 PolarHBondContact O-N 2.95Å; V402-Q475 WeakPolarHBondContact CG2-O 3.35Å; V402-Q479 HydrophobicContact CG1-CG 3.64Å; V402-W481 HydrophobicContact CG1-CH2 4.43Å; V402-W481 HydrophobicContact CG1-CZ2 3.95Å
403	A	64.5	Low	59.9	Low	1 Å²	1	59.8 Å²	59.8	1%	0.008	31%	0.314	C	S	.	.	H	α-helix	trans	-99.3	-21.2	-173.2	0	0	0	0	0	115.2	Q399 L400 D401 P415 A418 W481	Q399-A403 VanDerWaalsContact O-CB 3.29Å; Q399-A403 WeakPolarHBondContact O-CB 3.09Å; Q399-A403 PolarHBondContact O-N 3.35Å; L400-A403 PolarHBondContact O-N 3.33Å; L400-A403 VanDerWaalsContact O-N 3.15Å; D401-A403 VanDerWaalsContact C-N 3.33Å; D401-A403 PolarHBondContact O-N 3.47Å; A403-P415 HydrophobicContact CB-CB 4.09Å; A403-A418 VanDerWaalsContact CB-CA 3.4Å; A403-A418 HydrophobicContact CB-CB 3.54Å; A403-W481 HydrophobicContact CB-CH2 4.31Å
404	D	53.3	Low	57.8	Low	38 Å²	38	63.3 Å²	63.3	20%	0.203	33%	0.331	C	S	.	.			trans	-106.7	5.5	-163.8	-151.2	20.3	0	0	0	117.3	L400 A406 S407 P415	L400-D404 WeakPolarHBondContact O-CB 3.32Å; L400-D404 PolarHBondContact O-N 2.98Å; D404-A406 PolarHBondContact O-N 2.87Å; D404-S407 PolarHBondContact O-N 2.85Å; D404-P415 HydrophobicContact CB-CB 3.65Å; D404-P415 HydrophobicContact CB-CG 3.6Å; D404-P415 VanDerWaalsContact CG-CD 3.42Å; D404-P415 VanDerWaalsContact CG-CG 3.4Å; D404-P415 VanDerWaalsContact OD1-CB 3.22Å; D404-P415 WeakPolarHBondContact OD1-CB 3.49Å; D404-P415 VanDerWaalsContact OD1-CD 3.3Å; D404-P415 WeakPolarHBondContact OD1-CD 3.43Å; D404-P415 WeakPolarHBondContact OD1-CG 3.43Å; D404-P415 WeakPolarHBondContact OD2-CD 3.42Å
405	Q	43.9	Very low	55.9	Low	95 Å²	95	63.9 Å²	63.9	44%	0.444	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.5	17.8	171.2	-66.2	-165.9	22.3	0	0	113.7	S407 K478	Q405-S407 VanDerWaalsContact C-N 3.28Å; Q405-K478 HydrophobicContact CB-CB 3.59Å; Q405-K478 HydrophobicContact CB-CD 3.68Å; Q405-K478 HydrophobicContact CB-CG 3.66Å; Q405-K478 HydrophobicContact CG-CB 4.18Å; Q405-K478 WeakPolarHBondContact O-CD 3.46Å; Q405-K478 WeakPolarHBondContact O-CE 3.36Å; Q405-K478 PolarHBondContact O-NZ 3.22Å
406	A	36.6	Very low	54.4	Low	54 Å²	54	67.8 Å²	67.8	45%	0.446	35%	0.351	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.1	-13.3	159.9	0	0	0	0	0	112.5	D404 S408	D404-A406 PolarHBondContact O-N 2.87Å; A406-S408 PolarHBondContact O-N 3.06Å
407	S	38	Very low	53.4	Low	28 Å²	28	68.1 Å²	68.1	20%	0.196	35%	0.349	C	S	.	.	S	Bend	trans	-81.6	91.8	171.2	-101.5	0	0	0	0	111.2	D404 Q405 K409 F411 F413	D404-S407 PolarHBondContact O-N 2.85Å; Q405-S407 VanDerWaalsContact C-N 3.28Å; S407-K409 VanDerWaalsContact C-N 3.32Å; S407-K409 PolarHBondContact O-N 3.02Å; S407-F411 WeakPolarHBondContact CB-O 3.5Å; S407-F411 PolarHBondContact OG-O 3.3Å; S407-F413 WeakPolarHBondContact OG-CD2 3.19Å; S407-F413 PolarHBondContact OG-N 3.28Å
408	S	34.7	Very low	52.6	Low	114 Å²	114	66.7 Å²	66.7	80%	0.797	34%	0.341	S	S	*	.			trans	-55.6	97.2	157.9	-82.3	0	0	0	0	109.4	A406 K410	A406-S408 PolarHBondContact O-N 3.06Å; S408-K410 PolarHBondContact O-N 3.48Å
409	K	35.5	Very low	51.5	Low	223 Å²	223	69.6 Å²	69.6	97%	0.97	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	31	-4.1	158.9	-99.3	179.8	179	177.6	0	123	S407	S407-K409 VanDerWaalsContact C-N 3.32Å; S407-K409 PolarHBondContact O-N 3.02Å
410	K	36.2	Very low	51.4	Low	192 Å²	192	70.2 Å²	70.2	84%	0.835	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-128.3	-11.1	-174.5	-153.8	169.8	-177.7	179.4	0	115.6	S408	S408-K410 PolarHBondContact O-N 3.48Å
411	F	34.3	Very low	51.4	Low	111 Å²	111	66.6 Å²	66.6	49%	0.487	35%	0.347	S	S	.	.			trans	-139.7	130.2	172.7	-105.9	-93.9	0	0	0	110.3	S407 F413	S407-F411 WeakPolarHBondContact CB-O 3.5Å; S407-F411 PolarHBondContact OG-O 3.3Å; F411-F413 HydrophobicContact CB-CD2 4.16Å; F411-F413 HydrophobicContact CB-CE1 4.19Å; F411-F413 HydrophobicContact CB-CE2 3.49Å; F411-F413 VanDerWaalsContact CB-CE2 3.49Å; F411-F413 HydrophobicContact CB-CZ 3.52Å; F411-F413 HydrophobicContact CD1-CE1 4.36Å; F411-F413 HydrophobicContact CD1-CZ 4.35Å; F411-F413 HydrophobicContact CG-CZ 4.13Å; F411-F413 PolarHBondContact O-N 2.84Å
412	T	37.2	Very low	51.5	Low	106 Å²	106	67.9 Å²	67.9	65%	0.65	35%	0.352	S	S	*	.			trans	-89.2	81	-177	-56.2	0	0	0	0	108.6
413	F	42.7	Very low	51.5	Low	92 Å²	92	69.1 Å²	69.1	40%	0.404	37%	0.365	S	S	.	.			trans	-71.7	152.9	177.5	-61.9	-71.3	0	0	0	110.2	S407 F411 P415	S407-F413 WeakPolarHBondContact OG-CD2 3.19Å; S407-F413 PolarHBondContact OG-N 3.28Å; F411-F413 HydrophobicContact CB-CD2 4.16Å; F411-F413 HydrophobicContact CB-CE1 4.19Å; F411-F413 HydrophobicContact CB-CE2 3.49Å; F411-F413 VanDerWaalsContact CB-CE2 3.49Å; F411-F413 HydrophobicContact CB-CZ 3.52Å; F411-F413 HydrophobicContact CD1-CE1 4.36Å; F411-F413 HydrophobicContact CD1-CZ 4.35Å; F411-F413 HydrophobicContact CG-CZ 4.13Å; F411-F413 PolarHBondContact O-N 2.84Å; F413-P415 WeakPolarHBondContact O-CD 3.43Å
414	I	43.4	Very low	52.3	Low	94 Å²	94	70.1 Å²	70.1	48%	0.482	37%	0.37	S	S	.	.			trans	-73.9	118	164.2	-66.7	174.7	0	0	0	106.5	K416	I414-K416 PolarHBondContact O-N 3.29Å
415	P	46.6	Very low	53.8	Low	12 Å²	12	68.3 Å²	68.3	8%	0.078	36%	0.361	C	S	.	.			trans	-62	105.9	177.5	20	-30.7	0	0	0	109.8	L400 A403 D404 F413 Y417 A418 S419	L400-P415 HydrophobicContact CD2-CG 4.22Å; A403-P415 HydrophobicContact CB-CB 4.09Å; D404-P415 HydrophobicContact CB-CB 3.65Å; D404-P415 HydrophobicContact CB-CG 3.6Å; D404-P415 VanDerWaalsContact CG-CD 3.42Å; D404-P415 VanDerWaalsContact CG-CG 3.4Å; D404-P415 VanDerWaalsContact OD1-CB 3.22Å; D404-P415 WeakPolarHBondContact OD1-CB 3.49Å; D404-P415 VanDerWaalsContact OD1-CD 3.3Å; D404-P415 WeakPolarHBondContact OD1-CD 3.43Å; D404-P415 WeakPolarHBondContact OD1-CG 3.43Å; D404-P415 WeakPolarHBondContact OD2-CD 3.42Å; F413-P415 WeakPolarHBondContact O-CD 3.43Å; P415-Y417 PolarHBondContact O-N 2.88Å; P415-A418 HydrophobicContact CB-CB 3.79Å; P415-A418 HydrophobicContact CG-CB 3.41Å; P415-A418 VanDerWaalsContact CG-CB 3.41Å; P415-A418 PolarHBondContact O-N 3.43Å; P415-S419 PolarHBondContact O-N 2.93Å
416	K	55	Low	55.7	Low	85 Å²	85	65.2 Å²	65.2	37%	0.37	35%	0.347	S	S	.	.	H	α-helix	trans	-48.2	-35	174.6	-177.6	179.9	170.9	-172.3	0	111.5	T264 I414 S419	T264-K416 PolarHBondContact O-NZ 3.12Å; T264-K416 PolarHBondContact OG1-NZ 3.45Å; T264-K416 VanDerWaalsContact OG1-NZ 3.13Å; I414-K416 PolarHBondContact O-N 3.29Å; K416-S419 PolarHBondContact O-OG 3.29Å
417	Y	62.4	Low	57.9	Low	30 Å²	30	63.6 Å²	63.6	12%	0.118	33%	0.331	C	S	.	.	H	α-helix	trans	-78.7	-26.8	179.2	-53.5	-55.6	0	0	0	114.3	P267 I271 P415 S419 V420 V421 W481 T482	P267-Y417 HydrophobicContact CG-CE1 4.38Å; I271-Y417 HydrophobicContact CD1-CD1 4.31Å; P415-Y417 PolarHBondContact O-N 2.88Å; Y417-S419 VanDerWaalsContact C-N 3.3Å; Y417-S419 PolarHBondContact O-N 2.83Å; Y417-V420 WeakPolarHBondContact O-CB 3.46Å; Y417-V420 PolarHBondContact O-N 3.44Å; Y417-V420 VanDerWaalsContact O-N 3.12Å; Y417-V421 WeakPolarHBondContact O-CG2 3.48Å; Y417-V421 PolarHBondContact O-N 3.35Å; Y417-W481 VanDerWaalsContact CB-CZ3 3.44Å; Y417-W481 HydrophobicContact CD1-CZ3 4.42Å; Y417-W481 HydrophobicContact CD2-CE3 4.36Å; Y417-W481 AromaticContact CD2-CZ3 3.9Å; Y417-W481 HydrophobicContact CD2-CZ3 3.9Å; Y417-W481 HydrophobicContact CG-CE3 4.29Å; Y417-W481 AromaticContact CG-CZ3 3.68Å; Y417-W481 HydrophobicContact CG-CZ3 3.68Å; Y417-T482 HydrophobicContact CD2-CG2 4.38Å
418	A	64.5	Low	60.4	Low	5 Å²	5	64.2 Å²	64.2	4%	0.041	33%	0.332	C	S	.	.	H	α-helix	trans	-67.3	-38.1	177.7	0	0	0	0	0	110.3	L400 A403 P415 V420 V421 M422	L400-A418 HydrophobicContact CD2-CB 3.91Å; A403-A418 VanDerWaalsContact CB-CA 3.4Å; A403-A418 HydrophobicContact CB-CB 3.54Å; P415-A418 HydrophobicContact CB-CB 3.79Å; P415-A418 HydrophobicContact CG-CB 3.41Å; P415-A418 VanDerWaalsContact CG-CB 3.41Å; P415-A418 PolarHBondContact O-N 3.43Å; A418-V420 VanDerWaalsContact C-N 3.26Å; A418-V420 PolarHBondContact O-N 2.98Å; A418-V421 PolarHBondContact O-N 3.35Å; A418-M422 VanDerWaalsContact O-CB 3.28Å; A418-M422 WeakPolarHBondContact O-CB 3.32Å; A418-M422 PolarHBondContact O-N 3.35Å
419	S	61.7	Low	63.1	Low	61 Å²	61	58.8 Å²	58.8	43%	0.427	29%	0.294	S	S	.	.	H	α-helix	trans	-63.4	-32.6	173.5	46.8	0	0	0	0	112.6	P415 K416 Y417 G423	P415-S419 PolarHBondContact O-N 2.93Å; K416-S419 PolarHBondContact O-OG 3.29Å; Y417-S419 VanDerWaalsContact C-N 3.3Å; Y417-S419 PolarHBondContact O-N 2.83Å; S419-G423 PolarHBondContact O-N 3.38Å
420	V	70.3	Confident	65.6	Low	26 Å²	26	48.2 Å²	48.2	16%	0.158	25%	0.248	C	C	.	.	H	α-helix	trans	-70.3	-47.5	175.1	176	0	0	0	0	110.5	V266 W268 I271 Y417 A418 M422 G423 I424	V266-V420 HydrophobicContact CG1-CG1 4.28Å; V266-V420 HydrophobicContact CG1-CG2 4.28Å; W268-V420 HydrophobicContact CE3-CG1 4.47Å; W268-V420 HydrophobicContact CH2-CG1 4.01Å; W268-V420 HydrophobicContact CZ3-CG1 3.83Å; I271-V420 HydrophobicContact CD1-CG1 4.2Å; Y417-V420 WeakPolarHBondContact O-CB 3.46Å; Y417-V420 PolarHBondContact O-N 3.44Å; Y417-V420 VanDerWaalsContact O-N 3.12Å; A418-V420 VanDerWaalsContact C-N 3.26Å; A418-V420 PolarHBondContact O-N 2.98Å; V420-M422 VanDerWaalsContact C-N 3.34Å; V420-M422 PolarHBondContact O-N 2.98Å; V420-G423 PolarHBondContact O-N 2.81Å; V420-G423 VanDerWaalsContact O-N 3.13Å; V420-I424 HydrophobicContact CG1-CD1 4.07Å; V420-I424 WeakPolarHBondContact O-CG1 3.34Å; V420-I424 PolarHBondContact O-N 2.89Å
421	V	73.6	Confident	68.3	Low	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-59.9	-44.7	176.5	171.5	0	0	0	0	110.9	I271 V277 Q399 Y417 A418 G423 I424 S425 W481	I271-V421 HydrophobicContact CG2-CG2 4.33Å; V277-V421 HydrophobicContact CG1-CG1 4.18Å; V277-V421 HydrophobicContact CG1-CG2 4.3Å; V277-V421 HydrophobicContact CG2-CG2 4.09Å; Q399-V421 HydrophobicContact CB-CG1 4.21Å; Y417-V421 WeakPolarHBondContact O-CG2 3.48Å; Y417-V421 PolarHBondContact O-N 3.35Å; A418-V421 PolarHBondContact O-N 3.35Å; V421-G423 VanDerWaalsContact C-N 3.34Å; V421-G423 PolarHBondContact O-N 3Å; V421-I424 PolarHBondContact O-N 2.89Å; V421-S425 WeakPolarHBondContact O-CB 3.35Å; V421-S425 PolarHBondContact O-N 3.3Å; V421-W481 HydrophobicContact CG2-CH2 4.36Å
422	M	75.3	Confident	71.1	Confident	58 Å²	58	36.5 Å²	36.5	29%	0.286	20%	0.2	S	C	.	.	H	α-helix	trans	-59.9	-43.2	173.8	179.4	56.5	108.5	0	0	111.5	Q399 A418 V420 S425 N426	Q399-M422 VanDerWaalsContact OE1-CB 3.3Å; Q399-M422 PolarHBondContact OE1-SD 3.29Å; A418-M422 VanDerWaalsContact O-CB 3.28Å; A418-M422 WeakPolarHBondContact O-CB 3.32Å; A418-M422 PolarHBondContact O-N 3.35Å; V420-M422 VanDerWaalsContact C-N 3.34Å; V420-M422 PolarHBondContact O-N 2.98Å; M422-S425 PolarHBondContact O-N 3.32Å; M422-N426 WeakPolarHBondContact O-CB 3.18Å; M422-N426 PolarHBondContact O-N 2.83Å; M422-N426 HydrophobicContact SD-CB 4.48Å
423	G	72.3	Confident	73.6	Confident	26 Å²	26	31.5 Å²	31.5	27%	0.268	17%	0.169	S	C	.	.	H	α-helix	trans	-60.9	-46.6	177.7	0	0	0	0	0	112.9	S419 V420 V421 T427	S419-G423 PolarHBondContact O-N 3.38Å; V420-G423 PolarHBondContact O-N 2.81Å; V420-G423 VanDerWaalsContact O-N 3.13Å; V421-G423 VanDerWaalsContact C-N 3.34Å; V421-G423 PolarHBondContact O-N 3Å; G423-T427 WeakPolarHBondContact O-CB 3.44Å; G423-T427 PolarHBondContact O-N 3.17Å; G423-T427 PolarHBondContact O-OG1 2.97Å
424	I	80.8	Confident	75.9	Confident	23 Å²	23	28.3 Å²	28.3	12%	0.118	16%	0.155	C	C	.	.	H	α-helix	trans	-61.7	-50.8	175.4	-65	166.2	0	0	0	110	W268 I271 L272 V281 V420 V421 N426 T427 I428	W268-I424 HydrophobicContact CZ3-CD1 4.24Å; I271-I424 HydrophobicContact CG2-CD1 3.97Å; L272-I424 HydrophobicContact CD2-CD1 4.06Å; V281-I424 HydrophobicContact CG2-CG2 4.37Å; V420-I424 HydrophobicContact CG1-CD1 4.07Å; V420-I424 WeakPolarHBondContact O-CG1 3.34Å; V420-I424 PolarHBondContact O-N 2.89Å; V421-I424 PolarHBondContact O-N 2.89Å; I424-N426 PolarHBondContact O-N 2.9Å; I424-T427 PolarHBondContact O-N 2.9Å; I424-I428 HydrophobicContact CG2-CD1 4.01Å; I424-I428 PolarHBondContact O-N 3.43Å; I424-I428 VanDerWaalsContact O-N 3.08Å
425	S	85.3	Confident	78.3	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-60.1	-47.7	-178	-175.3	0	0	0	0	111.6	H284 V421 M422 T427 I428 A429	H284-S425 WeakPolarHBondContact CB-OG 3.3Å; H284-S425 PolarHBondContact ND1-OG 2.69Å; V421-S425 WeakPolarHBondContact O-CB 3.35Å; V421-S425 PolarHBondContact O-N 3.3Å; M422-S425 PolarHBondContact O-N 3.32Å; S425-T427 PolarHBondContact O-N 3.39Å; S425-I428 PolarHBondContact O-N 3.07Å; S425-A429 WeakPolarHBondContact O-CB 3.5Å; S425-A429 PolarHBondContact O-N 3.46Å
426	N	82.5	Confident	80.5	Confident	30 Å²	30	27.3 Å²	27.3	16%	0.16	15%	0.15	C	C	.	.	H	α-helix	trans	-66.7	-34.2	179	-168.3	54.1	0	0	0	112.8	Q99 M422 I424 T430	Q99-N426 PolarHBondContact NE2-ND2 3.21Å; Q99-N426 PolarHBondContact OE1-ND2 3.43Å; M422-N426 WeakPolarHBondContact O-CB 3.18Å; M422-N426 PolarHBondContact O-N 2.83Å; M422-N426 HydrophobicContact SD-CB 4.48Å; I424-N426 PolarHBondContact O-N 2.9Å; N426-T430 WeakPolarHBondContact O-CB 3.22Å; N426-T430 PolarHBondContact O-N 2.94Å; N426-T430 PolarHBondContact O-OG1 3.34Å
427	T	84	Confident	82.4	Confident	19 Å²	19	23.2 Å²	23.2	12%	0.117	13%	0.132	C	C	.	.	H	α-helix	trans	-63.4	-50.9	175	-58.3	0	0	0	0	110.5	L96 L100 G423 I424 S425 T430	L96-T427 HydrophobicContact CD1-CG2 3.7Å; L96-T427 WeakPolarHBondContact CD1-O 3.42Å; L100-T427 HydrophobicContact CD1-CG2 4.33Å; L100-T427 HydrophobicContact CD2-CG2 4.21Å; L100-T427 HydrophobicContact CG-CG2 4.11Å; G423-T427 WeakPolarHBondContact O-CB 3.44Å; G423-T427 PolarHBondContact O-N 3.17Å; G423-T427 PolarHBondContact O-OG1 2.97Å; I424-T427 PolarHBondContact O-N 2.9Å; S425-T427 PolarHBondContact O-N 3.39Å; T427-T430 WeakPolarHBondContact O-CB 3.44Å; T427-T430 PolarHBondContact O-N 3.07Å
428	I	90.1	Very high	83.9	Confident	42 Å²	42	24.2 Å²	24.2	22%	0.215	14%	0.139	C	C	.	.	H	α-helix	trans	-66.4	-42.6	179.1	-67.7	168.1	0	0	0	110.5	W278 V281 F285 I424 S425 T430 L431	W278-I428 HydrophobicContact CH2-CD1 3.93Å; W278-I428 HydrophobicContact CZ3-CD1 3.8Å; V281-I428 HydrophobicContact CG1-CB 3.96Å; V281-I428 HydrophobicContact CG1-CD1 3.6Å; V281-I428 HydrophobicContact CG1-CG1 4.38Å; V281-I428 HydrophobicContact CG1-CG2 3.78Å; F285-I428 HydrophobicContact CD2-CG2 3.82Å; F285-I428 WeakPolarHBondContact CD2-O 3.42Å; F285-I428 HydrophobicContact CE2-CG2 4.48Å; I424-I428 HydrophobicContact CG2-CD1 4.01Å; I424-I428 PolarHBondContact O-N 3.43Å; I424-I428 VanDerWaalsContact O-N 3.08Å; S425-I428 PolarHBondContact O-N 3.07Å; I428-T430 PolarHBondContact O-N 3.44Å; I428-L431 VanDerWaalsContact O-CB 3.28Å; I428-L431 WeakPolarHBondContact O-CB 3.31Å; I428-L431 WeakPolarHBondContact O-CG 3.36Å; I428-L431 PolarHBondContact O-N 2.98Å; I428-L431 VanDerWaalsContact O-N 3.09Å
429	A	90.9	Very high	85.3	Confident	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-74.1	-3.9	-179	0	0	0	0	0	113.9	H284 N288 Y292 S425 P432	H284-A429 HydrophobicContact CB-CB 4.11Å; N288-A429 HydrophobicContact CB-CB 4.22Å; N288-A429 WeakPolarHBondContact CB-O 3.37Å; N288-A429 WeakPolarHBondContact ND2-CB 3.32Å; N288-A429 PolarHBondContact ND2-O 2.82Å; Y292-A429 WeakPolarHBondContact CE2-O 3.48Å; S425-A429 WeakPolarHBondContact O-CB 3.5Å; S425-A429 PolarHBondContact O-N 3.46Å; A429-P432 WeakPolarHBondContact O-CD 3.24Å
430	T	89	Confident	86.9	Confident	0 Å²	0	23.7 Å²	23.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-81.4	-25.7	168.1	-63.6	0	0	0	0	112	F92 Y95 L96 N426 T427 I428 P432 G433	F92-T430 HydrophobicContact CB-CG2 4.41Å; F92-T430 HydrophobicContact CD1-CG2 4.12Å; Y95-T430 HydrophobicContact CD1-CG2 3.72Å; Y95-T430 HydrophobicContact CE1-CG2 4.38Å; L96-T430 HydrophobicContact CB-CG2 4.16Å; L96-T430 HydrophobicContact CD1-CG2 4.23Å; N426-T430 WeakPolarHBondContact O-CB 3.22Å; N426-T430 PolarHBondContact O-N 2.94Å; N426-T430 PolarHBondContact O-OG1 3.34Å; T427-T430 WeakPolarHBondContact O-CB 3.44Å; T427-T430 PolarHBondContact O-N 3.07Å; I428-T430 PolarHBondContact O-N 3.44Å; T430-P432 VanDerWaalsContact C-CD 3.41Å; T430-G433 PolarHBondContact O-N 3.38Å
431	L	92.2	Very high	87.9	Confident	58 Å²	58	22.5 Å²	22.5	30%	0.304	12%	0.124	S	C	.	.	H	α-helix	trans	-56.4	-38.3	-178.2	-64.3	172.3	0	0	0	114.4	L96 F285 I428 G433 M434 I435	L96-L431 HydrophobicContact CD1-CD2 4.42Å; L96-L431 HydrophobicContact CD2-CD2 3.76Å; F285-L431 HydrophobicContact CE2-CB 4.1Å; I428-L431 VanDerWaalsContact O-CB 3.28Å; I428-L431 WeakPolarHBondContact O-CB 3.31Å; I428-L431 WeakPolarHBondContact O-CG 3.36Å; I428-L431 PolarHBondContact O-N 2.98Å; I428-L431 VanDerWaalsContact O-N 3.09Å; L431-G433 PolarHBondContact O-N 3.13Å; L431-M434 HydrophobicContact CD2-SD 4.19Å; L431-M434 WeakPolarHBondContact O-CB 3.36Å; L431-M434 PolarHBondContact O-N 3.02Å; L431-I435 HydrophobicContact CB-CD1 4.27Å; L431-I435 WeakPolarHBondContact O-CG1 3.15Å; L431-I435 PolarHBondContact O-N 3.29Å
432	P	93.3	Very high	88.9	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-58.1	-30.6	175.3	-23.9	33.6	0	0	0	113.7	F285 W289 Y292 A429 T430 M434 I435 S436	F285-P432 HydrophobicContact CD1-CG 4.3Å; F285-P432 HydrophobicContact CD2-CG 3.69Å; F285-P432 HydrophobicContact CE1-CG 4.12Å; F285-P432 HydrophobicContact CE2-CG 3.53Å; F285-P432 HydrophobicContact CG-CG 4.1Å; F285-P432 HydrophobicContact CZ-CG 3.76Å; W289-P432 VanDerWaalsContact CA-CB 3.48Å; W289-P432 HydrophobicContact CB-CB 3.94Å; W289-P432 HydrophobicContact CB-CG 4.19Å; W289-P432 HydrophobicContact CD2-CB 4.34Å; W289-P432 HydrophobicContact CE3-CB 3.76Å; W289-P432 HydrophobicContact CE3-CG 4.25Å; W289-P432 HydrophobicContact CG-CB 4.48Å; Y292-P432 HydrophobicContact CD2-CB 4.36Å; A429-P432 WeakPolarHBondContact O-CD 3.24Å; T430-P432 VanDerWaalsContact C-CD 3.41Å; P432-M434 PolarHBondContact O-N 3.37Å; P432-I435 PolarHBondContact O-N 3.38Å; P432-S436 WeakPolarHBondContact O-CB 3.3Å; P432-S436 PolarHBondContact O-N 2.97Å
433	G	89.9	Confident	89.9	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-65.7	-21	175	0	0	0	0	0	113.4	F92 T430 L431 P437	F92-G433 VanDerWaalsContact CD2-C 3.43Å; F92-G433 WeakPolarHBondContact CD2-O 3.4Å; T430-G433 PolarHBondContact O-N 3.38Å; L431-G433 PolarHBondContact O-N 3.13Å; G433-P437 VanDerWaalsContact O-CD 3.26Å; G433-P437 WeakPolarHBondContact O-CD 3.42Å; G433-P437 WeakPolarHBondContact O-CG 3.34Å
434	M	90	Very high	90.9	Very high	25 Å²	25	23 Å²	23	12%	0.123	13%	0.128	C	C	.	.	H	α-helix	trans	-90.9	-44.8	174	-60.3	161.3	56.8	0	0	111.5	F92 Y93 L96 L431 P432	F92-M434 HydrophobicContact CB-CG 3.55Å; Y93-M434 HydrophobicContact CD1-CE 3.51Å; Y93-M434 HydrophobicContact CD2-CE 4.46Å; Y93-M434 HydrophobicContact CD2-CG 4.04Å; Y93-M434 HydrophobicContact CE1-CE 3.53Å; Y93-M434 HydrophobicContact CE2-CB 4.07Å; Y93-M434 HydrophobicContact CE2-CG 4.11Å; Y93-M434 HydrophobicContact CG-CE 3.99Å; Y93-M434 HydrophobicContact CG-CG 4.35Å; L96-M434 HydrophobicContact CB-SD 4.2Å; L96-M434 HydrophobicContact CD2-CE 4.15Å; L96-M434 HydrophobicContact CD2-SD 3.66Å; L96-M434 HydrophobicContact CG-SD 4.49Å; L431-M434 HydrophobicContact CD2-SD 4.19Å; L431-M434 WeakPolarHBondContact O-CB 3.36Å; L431-M434 PolarHBondContact O-N 3.02Å; P432-M434 PolarHBondContact O-N 3.37Å
435	I	94	Very high	91.3	Very high	83 Å²	83	27.9 Å²	27.9	43%	0.426	15%	0.148	S	C	.	.	H	α-helix	trans	-77.3	-46.9	-172	-60.8	168.2	0	0	0	111.3	W289 L431 P432 L438 L439	W289-I435 HydrophobicContact CH2-CG2 4.12Å; W289-I435 HydrophobicContact CZ3-CB 4.28Å; W289-I435 HydrophobicContact CZ3-CG2 3.95Å; L431-I435 HydrophobicContact CB-CD1 4.27Å; L431-I435 WeakPolarHBondContact O-CG1 3.15Å; L431-I435 PolarHBondContact O-N 3.29Å; P432-I435 PolarHBondContact O-N 3.38Å; I435-L438 PolarHBondContact O-N 2.82Å; I435-L439 WeakPolarHBondContact O-CB 3.46Å; I435-L439 PolarHBondContact O-N 3.28Å
436	S	94.3	Very high	91.3	Very high	2 Å²	2	35 Å²	35	1%	0.014	18%	0.181	C	C	.	.	H	α-helix	trans	-60.8	-47.3	-173.3	170.5	0	0	0	0	112.2	T293 P432 L438 L439 V440	T293-S436 WeakPolarHBondContact CB-OG 3.45Å; T293-S436 WeakPolarHBondContact CG2-OG 3.36Å; T293-S436 WeakPolarHBondContact OG1-CB 3.32Å; T293-S436 PolarHBondContact OG1-OG 2.88Å; P432-S436 WeakPolarHBondContact O-CB 3.3Å; P432-S436 PolarHBondContact O-N 2.97Å; S436-L438 VanDerWaalsContact C-N 3.31Å; S436-L438 PolarHBondContact O-N 3.44Å; S436-L439 WeakPolarHBondContact O-CB 3.25Å; S436-L439 PolarHBondContact O-N 3.32Å; S436-L439 VanDerWaalsContact O-N 3.09Å; S436-V440 WeakPolarHBondContact O-CG2 3.31Å; S436-V440 PolarHBondContact O-N 3.33Å
437	P	93.4	Very high	91.5	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-62	-36.9	-179.3	-28.9	38.9	0	0	0	114.3	G85 L88 T296 Y297 G433 G441	G85-P437 VanDerWaalsContact CA-O 3.32Å; G85-P437 WeakPolarHBondContact CA-O 3.47Å; G85-P437 VanDerWaalsContact O-CB 3.28Å; G85-P437 WeakPolarHBondContact O-CB 3.43Å; L88-P437 HydrophobicContact CB-CB 4.24Å; T296-P437 HydrophobicContact CG2-CG 4.09Å; Y297-P437 HydrophobicContact CE2-CB 3.9Å; Y297-P437 PolarHBondContact OH-O 3.43Å; G433-P437 VanDerWaalsContact O-CD 3.26Å; G433-P437 WeakPolarHBondContact O-CD 3.42Å; G433-P437 WeakPolarHBondContact O-CG 3.34Å; P437-G441 PolarHBondContact O-N 3.46Å
438	L	93.9	Very high	91.7	Very high	51 Å²	51	39 Å²	39	27%	0.267	20%	0.2	S	C	.	.	H	α-helix	trans	-66.9	-41.2	174.1	-72.4	176	0	0	0	112	A86 Y93 I435 S436 G441 A442	A86-L438 HydrophobicContact CB-CD2 3.77Å; Y93-L438 VanDerWaalsContact OH-CD1 3.27Å; Y93-L438 WeakPolarHBondContact OH-CD1 3.19Å; I435-L438 PolarHBondContact O-N 2.82Å; S436-L438 VanDerWaalsContact C-N 3.31Å; S436-L438 PolarHBondContact O-N 3.44Å; L438-G441 PolarHBondContact O-N 2.89Å; L438-A442 WeakPolarHBondContact O-CB 3.41Å; L438-A442 PolarHBondContact O-N 3.01Å
439	L	95.1	Very high	91.7	Very high	54 Å²	54	40.1 Å²	40.1	28%	0.283	21%	0.206	S	C	.	.	H	α-helix	trans	-64.7	-44.4	178.3	-176.6	64.6	0	0	0	111.4	W289 I435 S436 A442 I443 I458	W289-L439 HydrophobicContact CH2-CD2 3.74Å; W289-L439 HydrophobicContact CZ2-CD2 3.85Å; I435-L439 WeakPolarHBondContact O-CB 3.46Å; I435-L439 PolarHBondContact O-N 3.28Å; S436-L439 WeakPolarHBondContact O-CB 3.25Å; S436-L439 PolarHBondContact O-N 3.32Å; S436-L439 VanDerWaalsContact O-N 3.09Å; L439-A442 PolarHBondContact O-N 2.94Å; L439-I443 HydrophobicContact CD1-CD1 3.7Å; L439-I443 HydrophobicContact CD1-CG1 4.38Å; L439-I443 HydrophobicContact CG-CD1 3.88Å; L439-I443 WeakPolarHBondContact O-CB 3.48Å; L439-I443 WeakPolarHBondContact O-CG1 3.41Å; L439-I443 PolarHBondContact O-N 2.94Å; L439-I458 HydrophobicContact CD2-CD1 4.04Å; L439-I458 HydrophobicContact CD2-CG2 4.36Å
440	V	94.7	Very high	91.7	Very high	1 Å²	1	43.4 Å²	43.4	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-61.6	-47.3	174.4	178.9	0	0	0	0	110.3	T293 Y297 S436 A442 I443 V444 W452 I455	T293-V440 HydrophobicContact CG2-CG2 4.27Å; Y297-V440 HydrophobicContact CD1-CB 4.44Å; Y297-V440 HydrophobicContact CD1-CG1 3.53Å; Y297-V440 HydrophobicContact CD2-CB 3.83Å; Y297-V440 HydrophobicContact CD2-CG1 3.79Å; Y297-V440 HydrophobicContact CD2-CG2 4.06Å; Y297-V440 HydrophobicContact CE1-CB 4.3Å; Y297-V440 HydrophobicContact CE1-CG1 3.55Å; Y297-V440 HydrophobicContact CE2-CB 3.72Å; Y297-V440 HydrophobicContact CE2-CG1 3.86Å; Y297-V440 HydrophobicContact CE2-CG2 4.38Å; Y297-V440 HydrophobicContact CG-CB 4.21Å; Y297-V440 HydrophobicContact CG-CG1 3.64Å; Y297-V440 HydrophobicContact CG-CG2 4.46Å; S436-V440 WeakPolarHBondContact O-CG2 3.31Å; S436-V440 PolarHBondContact O-N 3.33Å; V440-A442 VanDerWaalsContact C-N 3.25Å; V440-A442 PolarHBondContact O-N 2.88Å; V440-I443 PolarHBondContact O-N 3.08Å; V440-V444 HydrophobicContact CG1-CB 4.31Å; V440-V444 HydrophobicContact CG1-CG2 3.92Å; V440-V444 WeakPolarHBondContact O-CB 3.42Å; V440-V444 PolarHBondContact O-N 3.15Å; V440-W452 HydrophobicContact CG1-CH2 4.3Å; V440-W452 HydrophobicContact CG1-CZ3 4.46Å; V440-I455 HydrophobicContact CB-CD1 4.41Å; V440-I455 HydrophobicContact CG2-CD1 3.95Å; V440-I455 HydrophobicContact CG2-CG1 4.21Å; V440-I455 HydrophobicContact CG2-CG2 3.91Å
441	G	92.5	Very high	91.9	Very high	1 Å²	1	44.8 Å²	44.8	1%	0.01	24%	0.235	C	C	.	.	H	α-helix	trans	-62.3	-27.9	176.8	0	0	0	0	0	114.6	S81 V82 P437 L438	S81-G441 CarbonylContact C-O 3.47Å; S81-G441 WeakPolarHBondContact CB-O 3.06Å; S81-G441 VanDerWaalsContact O-CA 3.26Å; S81-G441 WeakPolarHBondContact O-CA 3.48Å; V82-G441 PolarHBondContact N-O 2.96Å; P437-G441 PolarHBondContact O-N 3.46Å; L438-G441 PolarHBondContact O-N 2.89Å
442	A	94.5	Very high	91.9	Very high	47 Å²	47	42.3 Å²	42.3	39%	0.388	22%	0.222	S	C	.	.	H	α-helix	trans	-80.9	-29.8	177.1	0	0	0	0	0	113.4	V82 L438 L439 V440 K445	V82-A442 HydrophobicContact CG2-CB 4.44Å; L438-A442 WeakPolarHBondContact O-CB 3.41Å; L438-A442 PolarHBondContact O-N 3.01Å; L439-A442 PolarHBondContact O-N 2.94Å; V440-A442 VanDerWaalsContact C-N 3.25Å; V440-A442 PolarHBondContact O-N 2.88Å; A442-K445 WeakPolarHBondContact O-CE 3.38Å
443	I	94.8	Very high	91.9	Very high	39 Å²	39	46.5 Å²	46.5	20%	0.2	24%	0.238	C	C	.	.	H	α-helix	trans	-92.9	-44.8	-177.7	-68.4	171.8	0	0	0	111.5	L439 V440 K445 E451 I454 I455 I458	L439-I443 HydrophobicContact CD1-CD1 3.7Å; L439-I443 HydrophobicContact CD1-CG1 4.38Å; L439-I443 HydrophobicContact CG-CD1 3.88Å; L439-I443 WeakPolarHBondContact O-CB 3.48Å; L439-I443 WeakPolarHBondContact O-CG1 3.41Å; L439-I443 PolarHBondContact O-N 2.94Å; V440-I443 PolarHBondContact O-N 3.08Å; I443-K445 PolarHBondContact O-N 3.31Å; I443-E451 HydrophobicContact CG2-CB 4.21Å; I443-E451 VanDerWaalsContact O-CG 3.29Å; I443-E451 WeakPolarHBondContact O-CG 3.14Å; I443-E451 VanDerWaalsContact O-OE1 3.11Å; I443-I454 HydrophobicContact CD1-CG2 4.02Å; I443-I454 HydrophobicContact CG2-CB 4.14Å; I443-I454 HydrophobicContact CG2-CD1 4.21Å; I443-I454 HydrophobicContact CG2-CG2 4.29Å; I443-I455 HydrophobicContact CB-CD1 3.95Å; I443-I455 HydrophobicContact CD1-CD1 3.63Å; I443-I455 HydrophobicContact CG1-CD1 4.35Å; I443-I455 HydrophobicContact CG2-CD1 4Å; I443-I455 HydrophobicContact CG2-CG1 4.37Å; I443-I458 HydrophobicContact CD1-CD1 4.08Å
444	V	93.1	Very high	92.2	Very high	8 Å²	8	50.4 Å²	50.4	5%	0.048	26%	0.258	C	S	.	.			trans	-91.5	83.1	-175.9	-173.9	0	0	0	0	108.9	S81 V440 E451 W452 I455	S81-V444 WeakPolarHBondContact CB-O 3.49Å; S81-V444 PolarHBondContact OG-O 3.03Å; V440-V444 HydrophobicContact CG1-CB 4.31Å; V440-V444 HydrophobicContact CG1-CG2 3.92Å; V440-V444 WeakPolarHBondContact O-CB 3.42Å; V440-V444 PolarHBondContact O-N 3.15Å; V444-E451 HydrophobicContact CB-CB 4.45Å; V444-E451 HydrophobicContact CG2-CB 4.1Å; V444-W452 HydrophobicContact CG1-CZ2 4.28Å; V444-W452 HydrophobicContact CG2-CD2 4.18Å; V444-W452 HydrophobicContact CG2-CG 4.42Å; V444-I455 HydrophobicContact CG2-CG1 3.94Å
445	K	89.9	Confident	92.5	Very high	125 Å²	125	49.5 Å²	49.5	54%	0.543	25%	0.253	S	S	.	.	S	Bend	trans	-95.6	-47.6	178.7	-64.7	-177.6	-175.5	177.2	0	110.8	A442 I443 K447 E451	A442-K445 WeakPolarHBondContact O-CE 3.38Å; I443-K445 PolarHBondContact O-N 3.31Å; K445-K447 VanDerWaalsContact C-N 3.35Å; K445-E451 PolarHBondContact N-OE1 3.29Å
446	E	85.2	Confident	92.5	Very high	149 Å²	149	45.8 Å²	45.8	70%	0.696	23%	0.234	S	C	*	.	S	Bend	trans	-94.1	4.7	-176	-57.2	-56.1	146.6	0	0	112.7	T448 E451	E446-T448 HydrophobicContact CB-CG2 3.81Å; E446-T448 PolarHBondContact O-N 2.94Å; E446-E451 PolarHBondContact N-OE1 3.09Å; E446-E451 PolarHBondContact N-OE2 2.91Å
447	K	86.8	Confident	92.6	Very high	83 Å²	83	51.9 Å²	51.9	36%	0.361	26%	0.258	S	S	.	.			trans	60.3	27.2	177.6	-60.2	172.9	159	-144.9	0	113.4	D304 K445 E451	D304-K447 HydrophobicContact CB-CB 4.02Å; D304-K447 WeakPolarHBondContact OD1-CD 3.35Å; D304-K447 WeakPolarHBondContact OD1-CE 3.25Å; D304-K447 IonicContact OD1-NZ 3.24Å; D304-K447 PolarHBondContact OD1-NZ 2.97Å; D304-K447 IonicContact OD2-NZ 3.44Å; K445-K447 VanDerWaalsContact C-N 3.35Å; K447-E451 PolarHBondContact N-OE2 2.86Å
448	T	88.9	Confident	92.8	Very high	51 Å²	51	54.6 Å²	54.6	31%	0.313	27%	0.272	S	S	.	.			trans	-85.4	154.3	-174.1	63	0	0	0	0	112.6	E446 S450 E451 W452	E446-T448 HydrophobicContact CB-CG2 3.81Å; E446-T448 PolarHBondContact O-N 2.94Å; T448-S450 PolarHBondContact O-N 3.49Å; T448-S450 PolarHBondContact OG1-OG 2.92Å; T448-S450 VanDerWaalsContact OG1-OG 3.07Å; T448-E451 PolarHBondContact N-OE2 3.4Å; T448-E451 PolarHBondContact O-N 3.23Å; T448-E451 VanDerWaalsContact OG1-CD 3.27Å; T448-E451 VanDerWaalsContact OG1-CG 3.23Å; T448-E451 WeakPolarHBondContact OG1-CG 3.08Å; T448-E451 PolarHBondContact OG1-N 2.89Å; T448-E451 PolarHBondContact OG1-OE2 3.33Å; T448-W452 VanDerWaalsContact O-CD1 3.28Å; T448-W452 PolarHBondContact O-N 2.9Å
449	I	88.9	Confident	92.9	Very high	65 Å²	65	52.2 Å²	52.2	33%	0.333	26%	0.259	S	S	.	.	H	α-helix	trans	-58.4	-36.3	175.3	-166	165.6	0	0	0	112.3	V305 E451 W452 R453	V305-I449 HydrophobicContact CG1-CB 4.1Å; V305-I449 HydrophobicContact CG1-CD1 4.08Å; V305-I449 HydrophobicContact CG1-CG1 3.93Å; I449-E451 PolarHBondContact O-N 3.47Å; I449-W452 PolarHBondContact O-N 3.39Å; I449-R453 VanDerWaalsContact O-CG 3.25Å; I449-R453 WeakPolarHBondContact O-CG 3.26Å; I449-R453 PolarHBondContact O-N 3.16Å
450	S	90.9	Very high	93	Very high	70 Å²	70	50.6 Å²	50.6	49%	0.49	25%	0.251	S	S	.	.	H	α-helix	trans	-63.2	-40	179.1	39.9	0	0	0	0	113	T448 R453 I454	T448-S450 PolarHBondContact O-N 3.49Å; T448-S450 PolarHBondContact OG1-OG 2.92Å; T448-S450 VanDerWaalsContact OG1-OG 3.07Å; S450-R453 PolarHBondContact O-N 3.46Å; S450-I454 PolarHBondContact O-N 2.97Å
451	E	93.5	Very high	93.2	Very high	28 Å²	28	52.4 Å²	52.4	13%	0.131	27%	0.27	C	S	.	.	H	α-helix	trans	-66.7	-43.9	176	-67.7	165.2	137.7	0	0	110.6	I443 V444 K445 E446 K447 T448 I449 R453 I454 I455	I443-E451 HydrophobicContact CG2-CB 4.21Å; I443-E451 VanDerWaalsContact O-CG 3.29Å; I443-E451 WeakPolarHBondContact O-CG 3.14Å; I443-E451 VanDerWaalsContact O-OE1 3.11Å; V444-E451 HydrophobicContact CB-CB 4.45Å; V444-E451 HydrophobicContact CG2-CB 4.1Å; K445-E451 PolarHBondContact N-OE1 3.29Å; E446-E451 PolarHBondContact N-OE1 3.09Å; E446-E451 PolarHBondContact N-OE2 2.91Å; K447-E451 PolarHBondContact N-OE2 2.86Å; T448-E451 PolarHBondContact N-OE2 3.4Å; T448-E451 PolarHBondContact O-N 3.23Å; T448-E451 VanDerWaalsContact OG1-CD 3.27Å; T448-E451 VanDerWaalsContact OG1-CG 3.23Å; T448-E451 WeakPolarHBondContact OG1-CG 3.08Å; T448-E451 PolarHBondContact OG1-N 2.89Å; T448-E451 PolarHBondContact OG1-OE2 3.33Å; I449-E451 PolarHBondContact O-N 3.47Å; E451-R453 VanDerWaalsContact C-N 3.3Å; E451-R453 PolarHBondContact O-N 2.78Å; E451-I454 WeakPolarHBondContact O-CB 3.37Å; E451-I454 PolarHBondContact O-N 2.85Å; E451-I454 VanDerWaalsContact O-N 3.11Å; E451-I455 PolarHBondContact O-N 2.64Å
452	W	92.4	Very high	93.4	Very high	6 Å²	6	54.7 Å²	54.7	2%	0.023	28%	0.281	C	S	.	.	H	α-helix	trans	-63	-34.3	176.2	-80.6	103.5	0	0	0	113.3	Y297 A300 Y301 V305 V440 V444 T448 I449 I454 I455 F456	Y297-W452 HydrophobicContact CD1-CH2 4Å; Y297-W452 HydrophobicContact CG-CH2 4.27Å; Y297-W452 WeakPolarHBondContact O-CH2 3.45Å; A300-W452 HydrophobicContact CB-CZ2 4.32Å; Y301-W452 HydrophobicContact CD2-CB 4.24Å; Y301-W452 AromaticContact CD2-CD2 3.63Å; Y301-W452 HydrophobicContact CD2-CD2 3.63Å; Y301-W452 AromaticContact CD2-CE3 3.85Å; Y301-W452 HydrophobicContact CD2-CE3 3.85Å; Y301-W452 AromaticContact CD2-CG 3.82Å; Y301-W452 HydrophobicContact CD2-CG 3.82Å; Y301-W452 HydrophobicContact CD2-CZ3 4.41Å; Y301-W452 HydrophobicContact CE2-CB 4.3Å; Y301-W452 HydrophobicContact CE2-CG 4.32Å; Y301-W452 HydrophobicContact CG-CD2 4.38Å; Y301-W452 HydrophobicContact CG-CE3 4.29Å; Y301-W452 HydrophobicContact CG-CZ3 4.43Å; V305-W452 HydrophobicContact CG2-CB 4.4Å; V305-W452 HydrophobicContact CG2-CG 3.84Å; V440-W452 HydrophobicContact CG1-CH2 4.3Å; V440-W452 HydrophobicContact CG1-CZ3 4.46Å; V444-W452 HydrophobicContact CG1-CZ2 4.28Å; V444-W452 HydrophobicContact CG2-CD2 4.18Å; V444-W452 HydrophobicContact CG2-CG 4.42Å; T448-W452 VanDerWaalsContact O-CD1 3.28Å; T448-W452 PolarHBondContact O-N 2.9Å; I449-W452 PolarHBondContact O-N 3.39Å; W452-I454 VanDerWaalsContact C-N 3.25Å; W452-I454 PolarHBondContact O-N 3.22Å; W452-I455 HydrophobicContact CE3-CB 4.47Å; W452-I455 WeakPolarHBondContact O-CB 3.3Å; W452-I455 PolarHBondContact O-N 3.25Å; W452-I455 VanDerWaalsContact O-N 3.12Å; W452-F456 HydrophobicContact CB-CE2 4.21Å; W452-F456 HydrophobicContact CE3-CZ 4.31Å; W452-F456 WeakPolarHBondContact O-CD2 3.48Å; W452-F456 PolarHBondContact O-N 3.01Å
453	R	94.3	Very high	93.5	Very high	88 Å²	88	52.7 Å²	52.7	33%	0.332	26%	0.264	S	S	.	.	H	α-helix	trans	-58.4	-38.9	173.6	-74.1	-179.2	170.2	162.5	-0.5	111.9	V369 I449 S450 E451 I455 F456 Y457	V369-R453 HydrophobicContact CB-CG 4.38Å; V369-R453 HydrophobicContact CG1-CB 4.16Å; V369-R453 HydrophobicContact CG1-CG 3.63Å; V369-R453 HydrophobicContact CG2-CG 4.39Å; V369-R453 PolarHBondContact O-NE 2.86Å; V369-R453 PolarHBondContact O-NH2 2.88Å; I449-R453 VanDerWaalsContact O-CG 3.25Å; I449-R453 WeakPolarHBondContact O-CG 3.26Å; I449-R453 PolarHBondContact O-N 3.16Å; S450-R453 PolarHBondContact O-N 3.46Å; E451-R453 VanDerWaalsContact C-N 3.3Å; E451-R453 PolarHBondContact O-N 2.78Å; R453-I455 VanDerWaalsContact C-N 3.34Å; R453-I455 PolarHBondContact O-N 3.43Å; R453-F456 PolarHBondContact O-N 2.92Å; R453-Y457 HydrophobicContact CB-CD2 4.49Å; R453-Y457 HydrophobicContact CB-CE2 4.16Å; R453-Y457 WeakPolarHBondContact O-CD2 3.46Å; R453-Y457 VanDerWaalsContact O-CG 3.32Å; R453-Y457 PolarHBondContact O-N 3.49Å
454	I	95.6	Very high	93.7	Very high	83 Å²	83	52.2 Å²	52.2	43%	0.426	27%	0.266	S	S	.	.	H	α-helix	trans	-61.1	-45.2	175.7	-59.3	168.9	0	0	0	110.1	I443 S450 E451 W452 F456 Y457 I458	I443-I454 HydrophobicContact CD1-CG2 4.02Å; I443-I454 HydrophobicContact CG2-CB 4.14Å; I443-I454 HydrophobicContact CG2-CD1 4.21Å; I443-I454 HydrophobicContact CG2-CG2 4.29Å; S450-I454 PolarHBondContact O-N 2.97Å; E451-I454 WeakPolarHBondContact O-CB 3.37Å; E451-I454 PolarHBondContact O-N 2.85Å; E451-I454 VanDerWaalsContact O-N 3.11Å; W452-I454 VanDerWaalsContact C-N 3.25Å; W452-I454 PolarHBondContact O-N 3.22Å; I454-F456 PolarHBondContact O-N 3.4Å; I454-Y457 PolarHBondContact O-N 3.2Å; I454-I458 HydrophobicContact CG2-CD1 3.98Å; I454-I458 VanDerWaalsContact O-CG1 3.31Å; I454-I458 WeakPolarHBondContact O-CG1 3.33Å; I454-I458 PolarHBondContact O-N 3.44Å
455	I	95.1	Very high	93.8	Very high	5 Å²	5	54 Å²	54	3%	0.026	28%	0.281	C	S	.	.	H	α-helix	trans	-60.8	-43.5	177.7	-58.3	-52.7	0	0	0	111.8	T293 V440 I443 V444 E451 W452 R453 I458 T459	T293-I455 HydrophobicContact CG2-CG2 3.96Å; V440-I455 HydrophobicContact CB-CD1 4.41Å; V440-I455 HydrophobicContact CG2-CD1 3.95Å; V440-I455 HydrophobicContact CG2-CG1 4.21Å; V440-I455 HydrophobicContact CG2-CG2 3.91Å; I443-I455 HydrophobicContact CB-CD1 3.95Å; I443-I455 HydrophobicContact CD1-CD1 3.63Å; I443-I455 HydrophobicContact CG1-CD1 4.35Å; I443-I455 HydrophobicContact CG2-CD1 4Å; I443-I455 HydrophobicContact CG2-CG1 4.37Å; V444-I455 HydrophobicContact CG2-CG1 3.94Å; E451-I455 PolarHBondContact O-N 2.64Å; W452-I455 HydrophobicContact CE3-CB 4.47Å; W452-I455 WeakPolarHBondContact O-CB 3.3Å; W452-I455 PolarHBondContact O-N 3.25Å; W452-I455 VanDerWaalsContact O-N 3.12Å; R453-I455 VanDerWaalsContact C-N 3.34Å; R453-I455 PolarHBondContact O-N 3.43Å; I455-I458 PolarHBondContact O-N 3.28Å; I455-T459 WeakPolarHBondContact O-CB 3.46Å; I455-T459 PolarHBondContact O-N 3.18Å; I455-T459 PolarHBondContact O-OG1 3.41Å
456	F	95.1	Very high	94.2	Very high	5 Å²	5	48.1 Å²	48.1	2%	0.022	26%	0.256	C	S	.	.	H	α-helix	trans	-69.2	-35.3	177.6	-66.2	-46.7	0	0	0	112.7	M294 Y301 V365 T368 V369 W452 R453 I454 T459 T460	M294-F456 HydrophobicContact CE-CD1 3.94Å; M294-F456 HydrophobicContact CE-CE1 3.65Å; M294-F456 HydrophobicContact SD-CE1 4.38Å; Y301-F456 HydrophobicContact CD1-CZ 4.04Å; Y301-F456 AromaticContact CD2-CE2 3.96Å; Y301-F456 HydrophobicContact CD2-CE2 3.96Å; Y301-F456 AromaticContact CD2-CZ 3.77Å; Y301-F456 HydrophobicContact CD2-CZ 3.77Å; Y301-F456 HydrophobicContact CE1-CE2 4.33Å; Y301-F456 AromaticContact CE1-CZ 3.87Å; Y301-F456 HydrophobicContact CE1-CZ 3.87Å; Y301-F456 AromaticContact CE2-CE2 3.44Å; Y301-F456 HydrophobicContact CE2-CE2 3.44Å; Y301-F456 VanDerWaalsContact CE2-CE2 3.44Å; Y301-F456 AromaticContact CE2-CZ 3.6Å; Y301-F456 HydrophobicContact CE2-CZ 3.6Å; Y301-F456 AromaticContact CG-CZ 3.98Å; Y301-F456 HydrophobicContact CG-CZ 3.98Å; Y301-F456 AromaticContact CZ-CE2 3.65Å; Y301-F456 AromaticContact CZ-CZ 3.66Å; V365-F456 HydrophobicContact CG1-CB 3.91Å; V365-F456 HydrophobicContact CG1-CD1 3.8Å; V365-F456 HydrophobicContact CG1-CG 4.21Å; T368-F456 HydrophobicContact CG2-CE2 4.15Å; T368-F456 HydrophobicContact CG2-CZ 4.16Å; V369-F456 HydrophobicContact CG2-CB 3.32Å; V369-F456 HydrophobicContact CG2-CD2 3.81Å; V369-F456 HydrophobicContact CG2-CG 3.97Å; W452-F456 HydrophobicContact CB-CE2 4.21Å; W452-F456 HydrophobicContact CE3-CZ 4.31Å; W452-F456 WeakPolarHBondContact O-CD2 3.48Å; W452-F456 PolarHBondContact O-N 3.01Å; R453-F456 PolarHBondContact O-N 2.92Å; I454-F456 PolarHBondContact O-N 3.4Å; F456-T459 PolarHBondContact O-N 2.86Å; F456-T460 VanDerWaalsContact O-CB 3.28Å; F456-T460 WeakPolarHBondContact O-CB 3.45Å; F456-T460 PolarHBondContact O-N 3.27Å; F456-T460 PolarHBondContact O-OG1 2.88Å
457	Y	97.2	Very high	94.7	Very high	131 Å²	131	41.1 Å²	41.1	51%	0.514	22%	0.224	S	C	.	.	H	α-helix	trans	-64.1	-44.1	172.6	-71.6	-46.1	0	0	0	112	L366 V369 R453 I454 T459 T460 G461	L366-Y457 HydrophobicContact CD1-CD1 3.89Å; L366-Y457 HydrophobicContact CD1-CE1 3.64Å; V369-Y457 HydrophobicContact CG1-CE1 4Å; V369-Y457 HydrophobicContact CG1-CE2 4.35Å; V369-Y457 WeakPolarHBondContact CG1-OH 3.23Å; R453-Y457 HydrophobicContact CB-CD2 4.49Å; R453-Y457 HydrophobicContact CB-CE2 4.16Å; R453-Y457 WeakPolarHBondContact O-CD2 3.46Å; R453-Y457 VanDerWaalsContact O-CG 3.32Å; R453-Y457 PolarHBondContact O-N 3.49Å; I454-Y457 PolarHBondContact O-N 3.2Å; Y457-T459 PolarHBondContact O-N 2.69Å; Y457-T460 PolarHBondContact O-N 2.88Å; Y457-G461 PolarHBondContact O-N 3.06Å
458	I	96.7	Very high	95.2	Very high	57 Å²	57	42 Å²	42	29%	0.292	23%	0.232	S	C	.	.	H	α-helix	trans	-60.2	-48.4	175.1	-66.4	170.3	0	0	0	109.9	W289 L439 I443 I454 I455 T460 G461 M462	W289-I458 HydrophobicContact CZ2-CG2 3.66Å; L439-I458 HydrophobicContact CD2-CD1 4.04Å; L439-I458 HydrophobicContact CD2-CG2 4.36Å; I443-I458 HydrophobicContact CD1-CD1 4.08Å; I454-I458 HydrophobicContact CG2-CD1 3.98Å; I454-I458 VanDerWaalsContact O-CG1 3.31Å; I454-I458 WeakPolarHBondContact O-CG1 3.33Å; I454-I458 PolarHBondContact O-N 3.44Å; I455-I458 PolarHBondContact O-N 3.28Å; I458-T460 VanDerWaalsContact C-N 3.35Å; I458-T460 PolarHBondContact O-N 3.29Å; I458-G461 PolarHBondContact O-N 3.33Å; I458-M462 HydrophobicContact CG2-CG 4.46Å; I458-M462 WeakPolarHBondContact O-CG 3.38Å; I458-M462 PolarHBondContact O-N 3.2Å
459	T	96.7	Very high	95.6	Very high	1 Å²	1	43 Å²	43	1%	0.006	24%	0.235	C	C	.	.	H	α-helix	trans	-61.8	-41.3	179.6	-57.5	0	0	0	0	112.1	W289 V365 I455 F456 Y457 M462 F463	W289-T459 PolarHBondContact NE1-OG1 2.99Å; V365-T459 HydrophobicContact CG1-CG2 4.31Å; I455-T459 WeakPolarHBondContact O-CB 3.46Å; I455-T459 PolarHBondContact O-N 3.18Å; I455-T459 PolarHBondContact O-OG1 3.41Å; F456-T459 PolarHBondContact O-N 2.86Å; Y457-T459 PolarHBondContact O-N 2.69Å; T459-M462 PolarHBondContact O-N 3.37Å; T459-F463 HydrophobicContact CG2-CD2 4.02Å; T459-F463 HydrophobicContact CG2-CE2 3.64Å; T459-F463 HydrophobicContact CG2-CZ 4.2Å; T459-F463 WeakPolarHBondContact O-CD2 3.42Å; T459-F463 WeakPolarHBondContact O-CG 3.32Å; T459-F463 PolarHBondContact O-N 3.47Å
460	T	97	Very high	95.8	Very high	19 Å²	19	40 Å²	40	12%	0.117	22%	0.219	C	C	.	.	H	α-helix	trans	-61.3	-45.8	174.1	-60.1	0	0	0	0	111	A362 L366 F456 Y457 I458 M462 F463 A464	A362-T460 HydrophobicContact CB-CG2 4.1Å; L366-T460 HydrophobicContact CB-CG2 4.09Å; F456-T460 VanDerWaalsContact O-CB 3.28Å; F456-T460 WeakPolarHBondContact O-CB 3.45Å; F456-T460 PolarHBondContact O-N 3.27Å; F456-T460 PolarHBondContact O-OG1 2.88Å; Y457-T460 PolarHBondContact O-N 2.88Å; I458-T460 VanDerWaalsContact C-N 3.35Å; I458-T460 PolarHBondContact O-N 3.29Å; T460-M462 VanDerWaalsContact C-N 3.34Å; T460-M462 PolarHBondContact O-N 2.87Å; T460-F463 PolarHBondContact O-N 3.48Å; T460-A464 WeakPolarHBondContact O-CB 3.32Å; T460-A464 PolarHBondContact O-N 3.31Å
461	G	97.2	Very high	96	Very high	39 Å²	39	40.7 Å²	40.7	40%	0.402	22%	0.216	S	C	.	.	H	α-helix	trans	-60.3	-42.2	176.1	0	0	0	0	0	112.5	Y457 I458 A464 A465	Y457-G461 PolarHBondContact O-N 3.06Å; I458-G461 PolarHBondContact O-N 3.33Å; G461-A464 PolarHBondContact O-N 3.48Å; G461-A465 VanDerWaalsContact O-CB 3.25Å; G461-A465 WeakPolarHBondContact O-CB 3.37Å; G461-A465 PolarHBondContact O-N 3.03Å
462	M	97	Very high	96	Very high	49 Å²	49	43.2 Å²	43.2	24%	0.241	24%	0.237	C	C	.	.	H	α-helix	trans	-61.6	-45.9	175.9	-71.3	-54.6	-52.5	0	0	112.2	F285 A286 W289 I458 T459 T460 G466	F285-M462 HydrophobicContact CD1-CE 3.56Å; F285-M462 HydrophobicContact CE1-CE 3.33Å; A286-M462 WeakPolarHBondContact CB-O 3.31Å; W289-M462 HydrophobicContact CD2-CG 3.91Å; W289-M462 HydrophobicContact CG-CB 4.08Å; W289-M462 HydrophobicContact CG-CG 3.9Å; I458-M462 HydrophobicContact CG2-CG 4.46Å; I458-M462 WeakPolarHBondContact O-CG 3.38Å; I458-M462 PolarHBondContact O-N 3.2Å; T459-M462 PolarHBondContact O-N 3.37Å; T460-M462 VanDerWaalsContact C-N 3.34Å; T460-M462 PolarHBondContact O-N 2.87Å; M462-G466 PolarHBondContact O-N 3.23Å
463	F	97.9	Very high	96	Very high	5 Å²	5	47.8 Å²	47.8	2%	0.022	26%	0.257	C	S	.	.	H	α-helix	trans	-64.7	-45.2	176.3	-71.7	-38.6	0	0	0	112.7	A286 L358 Q361 A362 V365 T459 T460 G466 A467	A286-F463 WeakPolarHBondContact O-CD1 3.38Å; A286-F463 VanDerWaalsContact O-CE1 3.23Å; A286-F463 WeakPolarHBondContact O-CE1 3.35Å; L358-F463 HydrophobicContact CD2-CD1 3.75Å; L358-F463 HydrophobicContact CD2-CE1 4.24Å; Q361-F463 HydrophobicContact CB-CD1 4.38Å; Q361-F463 HydrophobicContact CB-CD2 3.79Å; Q361-F463 HydrophobicContact CB-CE1 4.33Å; Q361-F463 HydrophobicContact CB-CE2 3.72Å; Q361-F463 HydrophobicContact CB-CG 4.1Å; Q361-F463 HydrophobicContact CB-CZ 3.96Å; Q361-F463 HydrophobicContact CG-CE2 4.31Å; Q361-F463 HydrophobicContact CG-CZ 4.15Å; A362-F463 HydrophobicContact CB-CB 3.77Å; V365-F463 HydrophobicContact CG2-CE2 3.97Å; T459-F463 HydrophobicContact CG2-CD2 4.02Å; T459-F463 HydrophobicContact CG2-CE2 3.64Å; T459-F463 HydrophobicContact CG2-CZ 4.2Å; T459-F463 WeakPolarHBondContact O-CD2 3.42Å; T459-F463 WeakPolarHBondContact O-CG 3.32Å; T459-F463 PolarHBondContact O-N 3.47Å; T460-F463 PolarHBondContact O-N 3.48Å; F463-G466 PolarHBondContact O-N 2.89Å; F463-A467 VanDerWaalsContact O-CB 3.3Å; F463-A467 WeakPolarHBondContact O-CB 3.43Å; F463-A467 PolarHBondContact O-N 3.43Å
464	A	97.4	Very high	95.7	Very high	29 Å²	29	43.7 Å²	43.7	24%	0.24	24%	0.242	C	C	.	.	H	α-helix	trans	-63.1	-47.3	178.7	0	0	0	0	0	111.4	T460 G461 G466 A467 L468	T460-A464 WeakPolarHBondContact O-CB 3.32Å; T460-A464 PolarHBondContact O-N 3.31Å; G461-A464 PolarHBondContact O-N 3.48Å; A464-G466 PolarHBondContact O-N 2.87Å; A464-A467 PolarHBondContact O-N 3.47Å; A464-L468 WeakPolarHBondContact O-CB 3.47Å; A464-L468 VanDerWaalsContact O-CG 3.25Å; A464-L468 WeakPolarHBondContact O-CG 3.39Å; A464-L468 PolarHBondContact O-N 3.19Å
465	A	97	Very high	95.1	Very high	46 Å²	46	43.7 Å²	43.7	38%	0.38	24%	0.241	S	C	.	.	H	α-helix	trans	-60.3	-45.5	176.2	0	0	0	0	0	111.5	G461 A467 L468 L469	G461-A465 VanDerWaalsContact O-CB 3.25Å; G461-A465 WeakPolarHBondContact O-CB 3.37Å; G461-A465 PolarHBondContact O-N 3.03Å; A465-A467 VanDerWaalsContact C-N 3.35Å; A465-A467 PolarHBondContact O-N 3.31Å; A465-L468 PolarHBondContact O-N 2.96Å; A465-L469 WeakPolarHBondContact O-CB 3.29Å; A465-L469 VanDerWaalsContact O-CG 3.28Å; A465-L469 WeakPolarHBondContact O-CG 3.38Å; A465-L469 PolarHBondContact O-N 2.73Å
466	G	96.9	Very high	94.1	Very high	2 Å²	2	43.7 Å²	43.7	2%	0.021	24%	0.241	C	C	.	.	H	α-helix	trans	-59.4	-44.2	175.6	0	0	0	0	0	112.9	M462 F463 A464 Y470	M462-G466 PolarHBondContact O-N 3.23Å; F463-G466 PolarHBondContact O-N 2.89Å; A464-G466 PolarHBondContact O-N 2.87Å; G466-Y470 VanDerWaalsContact O-CB 3.23Å; G466-Y470 WeakPolarHBondContact O-CB 3.18Å; G466-Y470 PolarHBondContact O-N 2.94Å
467	A	97.1	Very high	93.1	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.008	26%	0.261	C	S	.	.	H	α-helix	trans	-64.9	-46.3	178.8	0	0	0	0	0	112.4	S355 L358 L359 F463 A464 A465 M471	S355-A467 WeakPolarHBondContact CB-O 3.24Å; S355-A467 PolarHBondContact OG-O 2.89Å; L358-A467 HydrophobicContact CB-CB 3.72Å; L358-A467 HydrophobicContact CD1-CB 4.43Å; L359-A467 HydrophobicContact CD2-CB 3.85Å; L359-A467 HydrophobicContact CG-CB 3.76Å; F463-A467 VanDerWaalsContact O-CB 3.3Å; F463-A467 WeakPolarHBondContact O-CB 3.43Å; F463-A467 PolarHBondContact O-N 3.43Å; A464-A467 PolarHBondContact O-N 3.47Å; A465-A467 VanDerWaalsContact C-N 3.35Å; A465-A467 PolarHBondContact O-N 3.31Å; A467-M471 WeakPolarHBondContact O-CB 3.21Å; A467-M471 PolarHBondContact O-N 3.45Å
468	L	96.8	Very high	91.5	Very high	103 Å²	103	44.4 Å²	44.4	54%	0.539	25%	0.253	S	S	.	.	H	α-helix	trans	-67.3	-47.5	-178.5	-70.1	173.5	0	0	0	111.4	A464 A465 Y470 M471 S472	A464-L468 WeakPolarHBondContact O-CB 3.47Å; A464-L468 VanDerWaalsContact O-CG 3.25Å; A464-L468 WeakPolarHBondContact O-CG 3.39Å; A464-L468 PolarHBondContact O-N 3.19Å; A465-L468 PolarHBondContact O-N 2.96Å; L468-Y470 VanDerWaalsContact C-N 3.33Å; L468-Y470 PolarHBondContact O-N 2.77Å; L468-M471 PolarHBondContact O-N 3.23Å; L468-S472 WeakPolarHBondContact O-CB 3.45Å; L468-S472 PolarHBondContact O-N 3.35Å; L468-S472 PolarHBondContact O-OG 2.88Å; L468-S472 VanDerWaalsContact O-OG 3.07Å
469	L	95.9	Very high	90.2	Very high	72 Å²	72	42.7 Å²	42.7	38%	0.377	24%	0.244	S	C	.	.	H	α-helix	trans	-62.7	-41.5	177.9	-69.9	172.1	0	0	0	111.3	V282 A465 S472 F473	V282-L469 HydrophobicContact CG1-CB 4Å; V282-L469 HydrophobicContact CG1-CD1 3.74Å; A465-L469 WeakPolarHBondContact O-CB 3.29Å; A465-L469 VanDerWaalsContact O-CG 3.28Å; A465-L469 WeakPolarHBondContact O-CG 3.38Å; A465-L469 PolarHBondContact O-N 2.73Å; L469-S472 PolarHBondContact O-N 3.12Å; L469-F473 HydrophobicContact CD2-CD2 4.16Å; L469-F473 HydrophobicContact CD2-CE2 3.85Å; L469-F473 WeakPolarHBondContact O-CB 3.28Å; L469-F473 WeakPolarHBondContact O-CD2 3.3Å; L469-F473 PolarHBondContact O-N 3.26Å
470	Y	94.9	Very high	88.4	Confident	0 Å²	0	47 Å²	47	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-65.6	-42.6	174	-168.4	-89.9	0	0	0	112	A279 I280 A283 K351 T354 S355 F395 N398 G466 L468 S472 A474	A279-Y470 HydrophobicContact CB-CD2 4.39Å; A279-Y470 WeakPolarHBondContact O-CD2 3.45Å; I280-Y470 HydrophobicContact CG1-CE2 4.06Å; A283-Y470 HydrophobicContact CB-CD2 3.44Å; A283-Y470 VanDerWaalsContact CB-CD2 3.44Å; A283-Y470 HydrophobicContact CB-CE2 4.07Å; A283-Y470 HydrophobicContact CB-CG 4Å; K351-Y470 HydrophobicContact CG-CE1 4.44Å; T354-Y470 HydrophobicContact CG2-CD1 3.73Å; T354-Y470 HydrophobicContact CG2-CD2 4.07Å; T354-Y470 HydrophobicContact CG2-CE1 3.7Å; T354-Y470 HydrophobicContact CG2-CE2 4.04Å; T354-Y470 HydrophobicContact CG2-CG 3.9Å; T354-Y470 WeakPolarHBondContact OG1-CE1 2.93Å; T354-Y470 PolarHBondContact OG1-OH 2.88Å; S355-Y470 WeakPolarHBondContact OG-CD1 3.41Å; F395-Y470 HydrophobicContact CB-CE2 4.09Å; N398-Y470 WeakPolarHBondContact CB-OH 3.42Å; N398-Y470 PolarHBondContact ND2-OH 3.06Å; G466-Y470 VanDerWaalsContact O-CB 3.23Å; G466-Y470 WeakPolarHBondContact O-CB 3.18Å; G466-Y470 PolarHBondContact O-N 2.94Å; L468-Y470 VanDerWaalsContact C-N 3.33Å; L468-Y470 PolarHBondContact O-N 2.77Å; Y470-S472 VanDerWaalsContact C-N 3.27Å; Y470-S472 PolarHBondContact O-N 2.99Å; Y470-A474 HydrophobicContact CD1-CB 3.72Å; Y470-A474 HydrophobicContact CD2-CB 3.94Å; Y470-A474 HydrophobicContact CE1-CB 3.63Å; Y470-A474 HydrophobicContact CE2-CB 3.87Å; Y470-A474 HydrophobicContact CG-CB 3.9Å; Y470-A474 WeakPolarHBondContact O-CA 3.32Å; Y470-A474 WeakPolarHBondContact O-CB 3.43Å; Y470-A474 PolarHBondContact O-N 2.83Å
471	M	94.6	Very high	86.8	Confident	85 Å²	85	46.4 Å²	46.4	42%	0.419	27%	0.269	S	S	.	.	H	α-helix	trans	-62.5	-36.5	178.7	-173.8	173	-83.5	0	0	111.5	K351 S355 A467 L468	K351-M471 WeakPolarHBondContact CD-O 3.19Å; K351-M471 WeakPolarHBondContact CE-O 3.42Å; K351-M471 PolarHBondContact NZ-O 2.94Å; S355-M471 PolarHBondContact OG-N 3.35Å; A467-M471 WeakPolarHBondContact O-CB 3.21Å; A467-M471 PolarHBondContact O-N 3.45Å; L468-M471 PolarHBondContact O-N 3.23Å
472	S	93.4	Very high	85	Confident	82 Å²	82	44.6 Å²	44.6	57%	0.573	25%	0.25	S	S	*	.	H	α-helix	trans	-75	-49.6	178.1	-61.9	0	0	0	0	112.3	L468 L469 Y470	L468-S472 WeakPolarHBondContact O-CB 3.45Å; L468-S472 PolarHBondContact O-N 3.35Å; L468-S472 PolarHBondContact O-OG 2.88Å; L468-S472 VanDerWaalsContact O-OG 3.07Å; L469-S472 PolarHBondContact O-N 3.12Å; Y470-S472 VanDerWaalsContact C-N 3.27Å; Y470-S472 PolarHBondContact O-N 2.99Å
473	F	92.1	Very high	82.9	Confident	101 Å²	101	48.2 Å²	48.2	44%	0.443	27%	0.265	S	S	.	.	H	α-helix	trans	-105.6	-13.8	-163.8	-65.6	-61.9	0	0	0	115.4	I275 A279 L469 Q475	I275-F473 HydrophobicContact CG2-CB 3.72Å; I275-F473 HydrophobicContact CG2-CD1 3.51Å; I275-F473 HydrophobicContact CG2-CE1 4.35Å; I275-F473 HydrophobicContact CG2-CG 3.78Å; A279-F473 HydrophobicContact CB-CB 3.85Å; L469-F473 HydrophobicContact CD2-CD2 4.16Å; L469-F473 HydrophobicContact CD2-CE2 3.85Å; L469-F473 WeakPolarHBondContact O-CB 3.28Å; L469-F473 WeakPolarHBondContact O-CD2 3.3Å; L469-F473 PolarHBondContact O-N 3.26Å; F473-Q475 PolarHBondContact O-N 3.42Å
474	A	87.1	Confident	80.6	Confident	2 Å²	2	51.2 Å²	51.2	2%	0.017	29%	0.285	C	S	.	.			trans	-65.7	134.3	-179.5	0	0	0	0	0	111.3	A279 V347 K351 Y470	A279-A474 HydrophobicContact CB-CB 4.31Å; V347-A474 WeakPolarHBondContact CG1-O 3.27Å; K351-A474 WeakPolarHBondContact CE-O 3.32Å; K351-A474 HydrophobicContact CG-CB 4.34Å; K351-A474 PolarHBondContact NZ-O 2.68Å; Y470-A474 HydrophobicContact CD1-CB 3.72Å; Y470-A474 HydrophobicContact CD2-CB 3.94Å; Y470-A474 HydrophobicContact CE1-CB 3.63Å; Y470-A474 HydrophobicContact CE2-CB 3.87Å; Y470-A474 HydrophobicContact CG-CB 3.9Å; Y470-A474 WeakPolarHBondContact O-CA 3.32Å; Y470-A474 WeakPolarHBondContact O-CB 3.43Å; Y470-A474 PolarHBondContact O-N 2.83Å
475	Q	84.7	Confident	78.2	Confident	84 Å²	84	55.1 Å²	55.1	39%	0.393	30%	0.298	S	S	.	.			trans	-125.4	154.6	169.4	-62.6	-178.1	-4.7	0	0	108.1	P276 N398 V402 F473	P276-Q475 HydrophobicContact CB-CB 4.05Å; P276-Q475 HydrophobicContact CB-CG 4.44Å; P276-Q475 HydrophobicContact CG-CB 3.88Å; P276-Q475 HydrophobicContact CG-CG 3.82Å; N398-Q475 PolarHBondContact ND2-O 3.26Å; N398-Q475 PolarHBondContact OD1-O 2.9Å; V402-Q475 WeakPolarHBondContact CG2-O 3.35Å; F473-Q475 PolarHBondContact O-N 3.42Å
476	A	74.2	Confident	75.8	Confident	4 Å²	4	56.2 Å²	56.2	3%	0.033	31%	0.307	C	S	.	.			trans	-128.1	31.3	174.1	0	0	0	0	0	110	L346 V347 R350 D401	L346-A476 HydrophobicContact CB-CB 4.45Å; L346-A476 HydrophobicContact CD2-CB 4.32Å; L346-A476 HydrophobicContact CG-CB 4.12Å; V347-A476 HydrophobicContact CB-CB 4.27Å; V347-A476 HydrophobicContact CG2-CB 3.74Å; R350-A476 HydrophobicContact CG-CB 4.32Å; D401-A476 HydrophobicContact CB-CB 4.08Å
477	T	72.9	Confident	73.1	Confident	71 Å²	71	61.1 Å²	61.1	44%	0.436	33%	0.329	S	S	.	.	S	Bend	trans	-112.7	151.8	177.4	48.7	0	0	0	0	109.9	Q479	T477-Q479 PolarHBondContact O-N 3.44Å; T477-Q479 PolarHBondContact O-NE2 3.32Å
478	K	63.5	Low	70.4	Confident	81 Å²	81	65.3 Å²	65.3	35%	0.352	35%	0.352	S	S	.	.			trans	-48.4	126.6	176.3	-167.1	169.6	-174.7	168.7	0	111	Q405 T482	Q405-K478 HydrophobicContact CB-CB 3.59Å; Q405-K478 HydrophobicContact CB-CD 3.68Å; Q405-K478 HydrophobicContact CB-CG 3.66Å; Q405-K478 HydrophobicContact CG-CB 4.18Å; Q405-K478 WeakPolarHBondContact O-CD 3.46Å; Q405-K478 WeakPolarHBondContact O-CE 3.36Å; Q405-K478 PolarHBondContact O-NZ 3.22Å; K478-T482 WeakPolarHBondContact CE-OG1 3.31Å; K478-T482 WeakPolarHBondContact CG-OG1 3.39Å
479	Q	69.1	Low	67.7	Low	21 Å²	21	65.8 Å²	65.8	10%	0.098	35%	0.351	C	S	.	.			trans	-88.2	148.8	173.9	-60.5	-62.7	-61.4	0	0	110.6	V402 T477 W481 T482	V402-Q479 HydrophobicContact CG1-CG 3.64Å; T477-Q479 PolarHBondContact O-N 3.44Å; T477-Q479 PolarHBondContact O-NE2 3.32Å; Q479-W481 HydrophobicContact CB-CD2 4.15Å; Q479-W481 HydrophobicContact CB-CG 4.26Å; Q479-W481 HydrophobicContact CB-CZ2 3.99Å; Q479-W481 VanDerWaalsContact CB-NE1 3.28Å; Q479-W481 HydrophobicContact CG-CZ2 4.17Å; Q479-W481 PolarHBondContact O-N 3.43Å; Q479-T482 PolarHBondContact O-N 3.18Å; Q479-T482 PolarHBondContact O-OG1 3.42Å
480	S	59.3	Low	65.4	Low	90 Å²	90	65.7 Å²	65.7	63%	0.629	35%	0.354	S	S	*	.	G	3₁₀ helix	trans	-54.1	-31.1	-175.4	53.8	0	0	0	0	113.9	T482 K483	S480-T482 PolarHBondContact O-N 2.9Å; S480-K483 PolarHBondContact O-N 3.36Å
481	W	64.6	Low	62.8	Low	7 Å²	7	70.4 Å²	70.4	3%	0.027	38%	0.378	C	S	.	.	G	3₁₀ helix	trans	-74.9	-2.9	-179.4	54	-104.2	0	0	0	115.1	P267 R270 I271 S274 V277 V402 A403 Y417 V421 Q479	P267-W481 HydrophobicContact CG-CB 4.41Å; R270-W481 HydrophobicContact CB-CB 3.58Å; R270-W481 HydrophobicContact CB-CG 4.2Å; R270-W481 HydrophobicContact CG-CB 4.4Å; I271-W481 HydrophobicContact CD1-CE3 4.49Å; I271-W481 HydrophobicContact CG1-CD2 3.99Å; I271-W481 HydrophobicContact CG1-CE3 3.97Å; I271-W481 HydrophobicContact CG1-CZ3 4.3Å; S274-W481 PolarHBondContact OG-NE1 2.93Å; V277-W481 HydrophobicContact CG2-CZ2 3.93Å; V402-W481 HydrophobicContact CG1-CH2 4.43Å; V402-W481 HydrophobicContact CG1-CZ2 3.95Å; A403-W481 HydrophobicContact CB-CH2 4.31Å; Y417-W481 VanDerWaalsContact CB-CZ3 3.44Å; Y417-W481 HydrophobicContact CD1-CZ3 4.42Å; Y417-W481 HydrophobicContact CD2-CE3 4.36Å; Y417-W481 AromaticContact CD2-CZ3 3.9Å; Y417-W481 HydrophobicContact CD2-CZ3 3.9Å; Y417-W481 HydrophobicContact CG-CE3 4.29Å; Y417-W481 AromaticContact CG-CZ3 3.68Å; Y417-W481 HydrophobicContact CG-CZ3 3.68Å; V421-W481 HydrophobicContact CG2-CH2 4.36Å; Q479-W481 HydrophobicContact CB-CD2 4.15Å; Q479-W481 HydrophobicContact CB-CG 4.26Å; Q479-W481 HydrophobicContact CB-CZ2 3.99Å; Q479-W481 VanDerWaalsContact CB-NE1 3.28Å; Q479-W481 HydrophobicContact CG-CZ2 4.17Å; Q479-W481 PolarHBondContact O-N 3.43Å
482	T	57.6	Low	60.5	Low	2 Å²	2	72.4 Å²	72.4	1%	0.012	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-89.3	-7	175.5	60.4	0	0	0	0	113.7	Y417 K478 Q479 S480	Y417-T482 HydrophobicContact CD2-CG2 4.38Å; K478-T482 WeakPolarHBondContact CE-OG1 3.31Å; K478-T482 WeakPolarHBondContact CG-OG1 3.39Å; Q479-T482 PolarHBondContact O-N 3.18Å; Q479-T482 PolarHBondContact O-OG1 3.42Å; S480-T482 PolarHBondContact O-N 2.9Å
483	K	53.1	Low	58.5	Low	124 Å²	124	75.2 Å²	75.2	54%	0.539	39%	0.39	S	S	.	.	S	Bend	trans	-69.2	127.6	175.1	-68.4	-170.3	177.7	-170.4	0	109.7	S480 E485	S480-K483 PolarHBondContact O-N 3.36Å; K483-E485 PolarHBondContact O-N 3.5Å
484	P	49.8	Very low	56.4	Low	69 Å²	69	76.4 Å²	76.4	45%	0.448	40%	0.398	S	S	.	.			trans	-61.7	133.4	171	-15.4	28.1	0	0	0	109.6	A486 E487	P484-A486 HydrophobicContact CB-CB 4.41Å; P484-A486 PolarHBondContact O-N 2.82Å; P484-E487 PolarHBondContact O-N 3.4Å; P484-E487 VanDerWaalsContact O-N 3.1Å
485	E	48.1	Very low	54.7	Low	111 Å²	111	81 Å²	81	52%	0.519	42%	0.422	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.7	-15.3	173.3	-73.7	169.8	161.5	0	0	113.2	K483 E487 D488 H489	K483-E485 PolarHBondContact O-N 3.5Å; E485-E487 PolarHBondContact O-N 2.96Å; E485-D488 PolarHBondContact O-N 3.03Å; E485-D488 VanDerWaalsContact O-N 3.1Å; E485-H489 PolarHBondContact O-N 3.24Å
486	A	45.3	Very low	53.3	Low	69 Å²	69	80 Å²	80	57%	0.57	43%	0.427	S	S	*	.	H	α-helix	trans	-60.7	-27	174.6	0	0	0	0	0	113.7	P484 T490	P484-A486 HydrophobicContact CB-CB 4.41Å; P484-A486 PolarHBondContact O-N 2.82Å; A486-T490 PolarHBondContact O-N 3.04Å; A486-T490 PolarHBondContact O-OG1 3.28Å
487	E	41	Very low	52.4	Low	104 Å²	104	82.4 Å²	82.4	49%	0.486	44%	0.444	S	S	.	.	H	α-helix	trans	-75	-30.7	174.2	-79.2	179.8	178.5	0	0	112.4	P484 E485 T490 L491	P484-E487 PolarHBondContact O-N 3.4Å; P484-E487 VanDerWaalsContact O-N 3.1Å; E485-E487 PolarHBondContact O-N 2.96Å; E487-T490 WeakPolarHBondContact CA-OG1 3.39Å; E487-T490 PolarHBondContact O-OG1 3.27Å; E487-L491 PolarHBondContact O-N 2.91Å
488	D	40.1	Very low	51.4	Low	89 Å²	89	82 Å²	82	48%	0.476	44%	0.444	S	S	.	.	H	α-helix	trans	-72.6	-37.2	178.6	-75.8	-19.4	0	0	0	110.8	E485 L491 E492	E485-D488 PolarHBondContact O-N 3.03Å; E485-D488 VanDerWaalsContact O-N 3.1Å; D488-L491 PolarHBondContact O-N 2.88Å; D488-E492 PolarHBondContact O-N 3.26Å
489	H	39.5	Very low	50.8	Low	114 Å²	114	84.3 Å²	84.3	53%	0.528	46%	0.456	S	S	.	.	H	α-helix	trans	-68.3	-34.9	175.1	-76.7	-51.8	0	0	0	113.4	E485 L491 E492 E493	E485-H489 PolarHBondContact O-N 3.24Å; H489-L491 VanDerWaalsContact C-N 3.29Å; H489-L491 PolarHBondContact O-N 3.18Å; H489-E492 IonicContact ND1-OE2 3.62Å; H489-E492 PolarHBondContact O-N 2.8Å; H489-E493 WeakPolarHBondContact O-CB 3.37Å; H489-E493 WeakPolarHBondContact O-CG 3.33Å; H489-E493 PolarHBondContact O-N 3.24Å
490	T	48.6	Very low	50.1	Low	70 Å²	70	87.9 Å²	87.9	43%	0.429	48%	0.479	S	S	.	.	H	α-helix	trans	-67.3	-30.5	172.5	37.9	0	0	0	0	112.8	A486 E487 Q494	A486-T490 PolarHBondContact O-N 3.04Å; A486-T490 PolarHBondContact O-OG1 3.28Å; E487-T490 WeakPolarHBondContact CA-OG1 3.39Å; E487-T490 PolarHBondContact O-OG1 3.27Å; T490-Q494 VanDerWaalsContact O-CB 3.27Å; T490-Q494 WeakPolarHBondContact O-CB 3.16Å; T490-Q494 WeakPolarHBondContact O-CG 3.07Å; T490-Q494 PolarHBondContact O-N 3.39Å
491	L	40.7	Very low	49.7	Very low	98 Å²	98	89.8 Å²	89.8	51%	0.513	48%	0.482	S	S	.	.	H	α-helix	trans	-74.7	-40.7	175.5	-101.9	144.6	0	0	0	111.8	E487 D488 H489 Q494 L495	E487-L491 PolarHBondContact O-N 2.91Å; D488-L491 PolarHBondContact O-N 2.88Å; H489-L491 VanDerWaalsContact C-N 3.29Å; H489-L491 PolarHBondContact O-N 3.18Å; L491-Q494 PolarHBondContact O-N 2.97Å; L491-L495 WeakPolarHBondContact O-CB 3.49Å; L491-L495 WeakPolarHBondContact O-CD1 3.48Å; L491-L495 WeakPolarHBondContact O-CG 3.18Å; L491-L495 PolarHBondContact O-N 3.12Å
492	E	46.8	Very low	48.9	Very low	127 Å²	127	93.5 Å²	93.5	59%	0.593	51%	0.509	S	S	*	.	H	α-helix	trans	-65.2	-41.4	172.9	-79.1	-177.8	157.9	0	0	112.1	D488 H489 L495 A496	D488-E492 PolarHBondContact O-N 3.26Å; H489-E492 IonicContact ND1-OE2 3.62Å; H489-E492 PolarHBondContact O-N 2.8Å; E492-L495 PolarHBondContact O-N 3.39Å; E492-A496 VanDerWaalsContact O-CB 3.29Å; E492-A496 WeakPolarHBondContact O-CB 3.47Å; E492-A496 PolarHBondContact O-N 3.32Å
493	E	50.2	Low	48.2	Very low	141 Å²	141	100 Å²	100	66%	0.659	54%	0.543	S	S	*	.	H	α-helix	trans	-65.5	-39.1	174.6	-79.6	-179.5	165	0	0	112	H489 A496 S497	H489-E493 WeakPolarHBondContact O-CB 3.37Å; H489-E493 WeakPolarHBondContact O-CG 3.33Å; H489-E493 PolarHBondContact O-N 3.24Å; E493-A496 PolarHBondContact O-N 3.42Å; E493-S497 WeakPolarHBondContact O-CB 3.36Å; E493-S497 PolarHBondContact O-N 3.48Å; E493-S497 PolarHBondContact O-OG 3.07Å
494	Q	49	Very low	47.6	Very low	127 Å²	127	99.7 Å²	99.7	59%	0.593	55%	0.552	S	S	*	*	H	α-helix	trans	-68.2	-37	175.4	-78.9	178.6	-7.6	0	0	112.9	T490 L491 S497 S498	T490-Q494 VanDerWaalsContact O-CB 3.27Å; T490-Q494 WeakPolarHBondContact O-CB 3.16Å; T490-Q494 WeakPolarHBondContact O-CG 3.07Å; T490-Q494 PolarHBondContact O-N 3.39Å; L491-Q494 PolarHBondContact O-N 2.97Å; Q494-S497 PolarHBondContact O-OG 3.43Å; Q494-S498 WeakPolarHBondContact O-CB 3.25Å; Q494-S498 PolarHBondContact O-N 3.42Å; Q494-S498 PolarHBondContact O-OG 3.2Å
495	L	51.3	Low	47.4	Very low	99 Å²	99	102.1 Å²	102.1	52%	0.518	57%	0.568	S	S	.	*	H	α-helix	trans	-68.5	-41.8	174.1	-79.3	160.9	0	0	0	110.9	L491 E492 S498 H499	L491-L495 WeakPolarHBondContact O-CB 3.49Å; L491-L495 WeakPolarHBondContact O-CD1 3.48Å; L491-L495 WeakPolarHBondContact O-CG 3.18Å; L491-L495 PolarHBondContact O-N 3.12Å; E492-L495 PolarHBondContact O-N 3.39Å; L495-S498 PolarHBondContact O-N 3.21Å; L495-S498 PolarHBondContact O-OG 3.23Å; L495-H499 PolarHBondContact O-CD2 3.37Å; L495-H499 VanDerWaalsContact O-CD2 3.3Å; L495-H499 PolarHBondContact O-N 2.9Å
496	A	54.3	Low	47.1	Very low	61 Å²	61	109.3 Å²	109.3	50%	0.504	60%	0.601	S	S	.	*	H	α-helix	trans	-64.7	-38.2	175.9	0	0	0	0	0	112.6	E492 E493 H499 T500	E492-A496 VanDerWaalsContact O-CB 3.29Å; E492-A496 WeakPolarHBondContact O-CB 3.47Å; E492-A496 PolarHBondContact O-N 3.32Å; E493-A496 PolarHBondContact O-N 3.42Å; A496-H499 PolarHBondContact O-N 3.31Å; A496-T500 PolarHBondContact O-N 3.47Å; A496-T500 PolarHBondContact O-OG1 3.02Å
497	S	54.9	Low	47.2	Very low	56 Å²	56	111.3 Å²	111.3	39%	0.392	60%	0.603	S	S	.	*	H	α-helix	trans	-70	-37.8	175.3	69.3	0	0	0	0	112	E493 Q494 H499 T500 D501	E493-S497 WeakPolarHBondContact O-CB 3.36Å; E493-S497 PolarHBondContact O-N 3.48Å; E493-S497 PolarHBondContact O-OG 3.07Å; Q494-S497 PolarHBondContact O-OG 3.43Å; S497-H499 VanDerWaalsContact C-N 3.25Å; S497-H499 PolarHBondContact O-N 3.2Å; S497-T500 WeakPolarHBondContact CA-OG1 3.23Å; S497-T500 PolarHBondContact O-N 2.9Å; S497-T500 VanDerWaalsContact O-N 3.11Å; S497-T500 PolarHBondContact O-OG1 3.11Å; S497-D501 PolarHBondContact O-N 3.45Å
498	S	53	Low	47.5	Very low	62 Å²	62	111.7 Å²	111.7	43%	0.434	61%	0.609	S	S	.	*	H	α-helix	trans	-64.6	-29.1	177.6	74	0	0	0	0	113.5	Q494 L495	Q494-S498 WeakPolarHBondContact O-CB 3.25Å; Q494-S498 PolarHBondContact O-N 3.42Å; Q494-S498 PolarHBondContact O-OG 3.2Å; L495-S498 PolarHBondContact O-N 3.21Å; L495-S498 PolarHBondContact O-OG 3.23Å
499	H	51.6	Low	47.9	Very low	130 Å²	130	112.9 Å²	112.9	60%	0.602	62%	0.616	S	S	*	*	H	α-helix	trans	-79.1	-21.3	175.1	-81.9	-62.7	0	0	0	113.7	L495 A496 S497 S502	L495-H499 PolarHBondContact O-CD2 3.37Å; L495-H499 VanDerWaalsContact O-CD2 3.3Å; L495-H499 PolarHBondContact O-N 2.9Å; A496-H499 PolarHBondContact O-N 3.31Å; S497-H499 VanDerWaalsContact C-N 3.25Å; S497-H499 PolarHBondContact O-N 3.2Å; H499-S502 PolarHBondContact O-OG 3.26Å; H499-S502 VanDerWaalsContact O-OG 3.13Å
500	T	52.5	Low	48.4	Very low	96 Å²	96	112.9 Å²	112.9	59%	0.589	62%	0.621	S	S	*	*	H	α-helix	trans	-83.2	-31.7	176.6	24.9	0	0	0	0	112.2	A496 S497 S502 L503	A496-T500 PolarHBondContact O-N 3.47Å; A496-T500 PolarHBondContact O-OG1 3.02Å; S497-T500 WeakPolarHBondContact CA-OG1 3.23Å; S497-T500 PolarHBondContact O-N 2.9Å; S497-T500 VanDerWaalsContact O-N 3.11Å; S497-T500 PolarHBondContact O-OG1 3.11Å; T500-S502 VanDerWaalsContact C-N 3.25Å; T500-S502 PolarHBondContact O-N 2.88Å; T500-L503 PolarHBondContact O-N 3.07Å
501	D	50.8	Low	48.4	Very low	129 Å²	129	115.6 Å²	115.6	69%	0.69	63%	0.633	S	S	*	*	H	α-helix	trans	-71.2	-16.6	176.9	-73.2	-21.6	0	0	0	113.9	S497 L503	S497-D501 PolarHBondContact O-N 3.45Å; D501-L503 VanDerWaalsContact C-N 3.32Å; D501-L503 PolarHBondContact O-N 3.27Å
502	S	49	Very low	48.9	Very low	85 Å²	85	116.7 Å²	116.7	59%	0.594	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84	1.4	175.7	58.2	0	0	0	0	115	H499 T500	H499-S502 PolarHBondContact O-OG 3.26Å; H499-S502 VanDerWaalsContact O-OG 3.13Å; T500-S502 VanDerWaalsContact C-N 3.25Å; T500-S502 PolarHBondContact O-N 2.88Å
503	L	43.5	Very low	49	Very low	140 Å²	140	116 Å²	116	73%	0.733	65%	0.645	S	S	*	*	T	Hydrogen-bonded Turn	trans	-118.5	21.9	-174.6	-77.4	171.1	0	0	0	115	T500 D501 P505	T500-L503 PolarHBondContact O-N 3.07Å; D501-L503 VanDerWaalsContact C-N 3.32Å; D501-L503 PolarHBondContact O-N 3.27Å; L503-P505 VanDerWaalsContact O-CD 3.31Å; L503-P505 WeakPolarHBondContact O-CD 3.29Å
504	T	39.2	Very low	49	Very low	117 Å²	117	114.1 Å²	114.1	72%	0.718	64%	0.644	S	S	*	*			trans	-97.5	102.3	162.6	26.3	0	0	0	0	110.1
505	P	45.9	Very low	49	Very low	120 Å²	120	113 Å²	113	78%	0.779	65%	0.648	S	S	*	*			trans	-70	128.7	167.2	-0.8	19	0	0	0	108.1	L503	L503-P505 VanDerWaalsContact O-CD 3.31Å; L503-P505 WeakPolarHBondContact O-CD 3.29Å
506	Q	41.7	Very low	48.7	Very low	261 Å²	261	114.3 Å²	114.3	100%	1.22	66%	0.659	S	S	*	*			trans	-59.7	0	154.1	-69.3	-176.5	-14.4	0	0	109.4

Retrieved 506 of 506 residues in 403.9 ms (Link to these results)

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