A0A077ZBZ1_TRITR Loading...

Multidrug resistance associated protein 4

AlphaFold DB , UniProt , Accession A0A077ZBZ1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 910 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M66.2Low79.5Confident117 Ų11761.6 Ų61.658%0.57632%0.318SS*.  0-54.70-167.3178.7-66.500111.2F3 C4 L5 R52 H53M1-F3 PolarHBondContact O-N 2.61Å; M1-C4 WeakPolarHBondContact O-CB 3.43Å; M1-C4 PolarHBondContact O-N 3.48Å; M1-C4 VanDerWaalsContact O-N 3.12Å; M1-L5 PolarHBondContact O-N 3.46Å; M1-L5 VanDerWaalsContact O-N 3.08Å; M1-R52 HydrophobicContact CE-CB 4Å; M1-R52 HydrophobicContact SD-CB 4.06Å; M1-H53 VanDerWaalsContact SD-CA 3.59Å; M1-H53 HydrophobicContact SD-CB 3.61Å
2W68.3Low80.3Confident60 Ų6056.6 Ų56.623%0.22729%0.292CS..Hα-helixtrans-52.8-46177.5-80.6119.1000114.9C4 L5 A6 H53 E118 F520W2-C4 VanDerWaalsContact C-N 3.26Å; W2-C4 PolarHBondContact O-N 3.29Å; W2-L5 HydrophobicContact CE3-CD2 3.72Å; W2-L5 HydrophobicContact CH2-CD2 4.41Å; W2-L5 HydrophobicContact CZ3-CD2 3.55Å; W2-L5 WeakPolarHBondContact O-CB 3.24Å; W2-L5 PolarHBondContact O-N 2.84Å; W2-A6 WeakPolarHBondContact O-CB 3.11Å; W2-A6 PolarHBondContact O-N 2.65Å; W2-H53 AromaticContact CE2-CE1 3.52Å; W2-H53 AromaticContact CE2-NE2 3.73Å; W2-H53 AromaticContact CH2-CD2 3.99Å; W2-H53 AromaticContact CH2-NE2 3.68Å; W2-H53 AromaticContact CZ2-CD2 3.7Å; W2-H53 AromaticContact CZ2-CE1 3.31Å; W2-H53 WeakPolarHBondContact CZ2-CE1 3.19Å; W2-H53 AromaticContact CZ2-NE2 3.04Å; W2-H53 WeakPolarHBondContact CZ2-NE2 3.47Å; W2-H53 AromaticContact NE1-CE1 3.57Å; W2-H53 AromaticContact NE1-ND1 4Å; W2-E118 HydrophobicContact CD2-CG 4.39Å; W2-E118 HydrophobicContact CG-CG 4.26Å; W2-E118 WeakPolarHBondContact CZ2-OE1 3.27Å; W2-E118 PolarHBondContact NE1-OE1 3.36Å; W2-E118 VanDerWaalsContact NE1-OE1 3.12Å; W2-F520 HydrophobicContact CH2-CE1 4.24Å; W2-F520 HydrophobicContact CH2-CE2 4.5Å; W2-F520 HydrophobicContact CH2-CZ 4Å
3F74.3Confident80.7Confident129 Ų12955.4 Ų55.457%0.56629%0.286SS*.Hα-helixtrans-53.1-43.5175.7-177.7-93.3000113.1M1 A7 V121M1-F3 PolarHBondContact O-N 2.61Å; F3-A7 WeakPolarHBondContact O-CB 3.11Å; F3-A7 PolarHBondContact O-N 3.2Å; F3-V121 HydrophobicContact CD2-CG1 4.06Å
4C82Confident81Confident50 Ų5053.6 Ų53.634%0.33828%0.28SS..Hα-helixtrans-73.1-32.2-179.7-161.40000111.8M1 W2 K8M1-C4 WeakPolarHBondContact O-CB 3.43Å; M1-C4 PolarHBondContact O-N 3.48Å; M1-C4 VanDerWaalsContact O-N 3.12Å; W2-C4 VanDerWaalsContact C-N 3.26Å; W2-C4 PolarHBondContact O-N 3.29Å; C4-K8 VanDerWaalsContact O-CG 3.22Å; C4-K8 WeakPolarHBondContact O-CG 3.37Å; C4-K8 PolarHBondContact O-N 3.4Å
5L81Confident81.5Confident8 Ų850.5 Ų50.54%0.04226%0.264CS..Hα-helixtrans-67.2-50.5172173.159.1000110.7M1 W2 A7 K8 S9 E46 K49 L50M1-L5 PolarHBondContact O-N 3.46Å; M1-L5 VanDerWaalsContact O-N 3.08Å; W2-L5 HydrophobicContact CE3-CD2 3.72Å; W2-L5 HydrophobicContact CH2-CD2 4.41Å; W2-L5 HydrophobicContact CZ3-CD2 3.55Å; W2-L5 WeakPolarHBondContact O-CB 3.24Å; W2-L5 PolarHBondContact O-N 2.84Å; L5-A7 PolarHBondContact O-N 3.14Å; L5-K8 PolarHBondContact O-N 3.36Å; L5-S9 PolarHBondContact O-N 3.27Å; L5-S9 PolarHBondContact O-OG 2.97Å; L5-E46 HydrophobicContact CD1-CG 3.76Å; L5-K49 HydrophobicContact CB-CB 4.39Å; L5-K49 HydrophobicContact CD1-CB 4.23Å; L5-L50 HydrophobicContact CD1-CD1 4.42Å; L5-L50 HydrophobicContact CD1-CD2 3.95Å; L5-L50 HydrophobicContact CD1-CG 3.67Å; L5-L50 HydrophobicContact CD2-CD2 3.5Å; L5-L50 VanDerWaalsContact CD2-CD2 3.5Å; L5-L50 HydrophobicContact CD2-CG 4.13Å; L5-L50 HydrophobicContact CG-CD2 4.37Å
6A77.9Confident81.9Confident27 Ų2747.3 Ų47.322%0.22325%0.247CC..Hα-helixtrans-56.6-48.2178.200000111.3W2 K8 S9 D10 R125W2-A6 WeakPolarHBondContact O-CB 3.11Å; W2-A6 PolarHBondContact O-N 2.65Å; A6-K8 VanDerWaalsContact C-N 3.26Å; A6-K8 PolarHBondContact O-N 2.87Å; A6-S9 PolarHBondContact O-N 3.15Å; A6-S9 VanDerWaalsContact O-N 3.12Å; A6-D10 WeakPolarHBondContact O-CB 3.04Å; A6-D10 PolarHBondContact O-N 3.38Å; A6-D10 VanDerWaalsContact O-OD2 3.11Å; A6-R125 VanDerWaalsContact CB-NH2 3.34Å
7A84.5Confident82.1Confident42 Ų4248.8 Ų48.835%0.34726%0.255SS..Hα-helixtrans-58.6-33.8176.200000113.9F3 L5 K11F3-A7 WeakPolarHBondContact O-CB 3.11Å; F3-A7 PolarHBondContact O-N 3.2Å; L5-A7 PolarHBondContact O-N 3.14Å; A7-K11 WeakPolarHBondContact O-CB 3.19Å; A7-K11 PolarHBondContact O-N 3.24Å; A7-K11 VanDerWaalsContact O-N 3.1Å
8K86.8Confident82.3Confident60 Ų6047.4 Ų47.426%0.26125%0.248SC..Hα-helixtrans-75.9-38.3176-68.1-67.1-177.8177.40112.1C4 L5 A6 R12 E45 E46C4-K8 VanDerWaalsContact O-CG 3.22Å; C4-K8 WeakPolarHBondContact O-CG 3.37Å; C4-K8 PolarHBondContact O-N 3.4Å; L5-K8 PolarHBondContact O-N 3.36Å; A6-K8 VanDerWaalsContact C-N 3.26Å; A6-K8 PolarHBondContact O-N 2.87Å; K8-R12 PolarHBondContact O-N 3.47Å; K8-R12 VanDerWaalsContact O-N 3.08Å; K8-E45 HydrophobicContact CD-CB 4.43Å; K8-E45 WeakPolarHBondContact CD-OE2 3.42Å; K8-E45 WeakPolarHBondContact CE-OE2 3.37Å; K8-E45 IonicContact NZ-OE2 3.85Å; K8-E45 PolarHBondContact NZ-OE2 3.34Å; K8-E46 HydrophobicContact CB-CB 4.48Å
9S83.7Confident82.6Confident14 Ų1445.1 Ų45.110%0.09824%0.236CC..Hα-helixtrans-63.9-43.6172.5-58.50000111.2L5 A6 R12 I13 E46L5-S9 PolarHBondContact O-N 3.27Å; L5-S9 PolarHBondContact O-OG 2.97Å; A6-S9 PolarHBondContact O-N 3.15Å; A6-S9 VanDerWaalsContact O-N 3.12Å; S9-R12 PolarHBondContact O-N 2.91Å; S9-I13 VanDerWaalsContact O-CG1 3.29Å; S9-I13 WeakPolarHBondContact O-CG1 3.22Å; S9-I13 PolarHBondContact O-N 3.47Å; S9-E46 VanDerWaalsContact OG-CD 3.32Å; S9-E46 PolarHBondContact OG-OE1 3.15Å
10D83.7Confident82.8Confident77 Ų7743.2 Ų43.241%0.41223%0.226SC..Hα-helixtrans-59.5-47176.6-62.9-23000110.3A6 R12 I13 S14 R125A6-D10 WeakPolarHBondContact O-CB 3.04Å; A6-D10 PolarHBondContact O-N 3.38Å; A6-D10 VanDerWaalsContact O-OD2 3.11Å; D10-R12 PolarHBondContact O-N 3.16Å; D10-I13 PolarHBondContact O-N 3.22Å; D10-S14 PolarHBondContact O-N 3.43Å; D10-R125 IonicContact OD2-CZ 3.55Å; D10-R125 IonicContact OD2-NH1 2.94Å; D10-R125 PolarHBondContact OD2-NH1 3.36Å; D10-R125 VanDerWaalsContact OD2-NH1 3.09Å; D10-R125 IonicContact OD2-NH2 3.87Å; D10-R125 PolarHBondContact OD2-NH2 3.25Å
11K86Confident82.8Confident94 Ų9445.3 Ų45.341%0.40924%0.237SC..Hα-helixtrans-57.5-46.2174-176.8-179.6178.8-175.40112.5A7 I13 S14 I15A7-K11 WeakPolarHBondContact O-CB 3.19Å; A7-K11 PolarHBondContact O-N 3.24Å; A7-K11 VanDerWaalsContact O-N 3.1Å; K11-I13 VanDerWaalsContact C-N 3.32Å; K11-I13 PolarHBondContact O-N 3.21Å; K11-S14 PolarHBondContact O-N 2.83Å; K11-I15 HydrophobicContact CG-CD1 3.99Å; K11-I15 VanDerWaalsContact O-CG1 3.31Å; K11-I15 WeakPolarHBondContact O-CG1 3.49Å; K11-I15 PolarHBondContact O-N 3.15Å; K11-I15 VanDerWaalsContact O-N 3.1Å
12R88.9Confident83.8Confident1 Ų139.9 Ų39.90%0.00421%0.211CC..Hα-helixtrans-62.8-40.8178.5-177-170.561.171.65.4111.3K8 S9 D10 M16 A42 E46 H485K8-R12 PolarHBondContact O-N 3.47Å; K8-R12 VanDerWaalsContact O-N 3.08Å; S9-R12 PolarHBondContact O-N 2.91Å; D10-R12 PolarHBondContact O-N 3.16Å; R12-M16 HydrophobicContact CG-SD 4.4Å; R12-M16 PolarHBondContact NH1-SD 3.08Å; R12-M16 WeakPolarHBondContact O-CB 3.31Å; R12-M16 WeakPolarHBondContact O-CG 3.31Å; R12-M16 PolarHBondContact O-N 3.07Å; R12-A42 HydrophobicContact CB-CB 4.17Å; R12-A42 HydrophobicContact CG-CB 4.23Å; R12-E46 WeakPolarHBondContact CD-OE2 3.46Å; R12-E46 IonicContact NE-OE2 3.3Å; R12-E46 PolarHBondContact NE-OE2 3.34Å; R12-H485 PolarHBondContact NH1-NE2 3.42Å
13I86.1Confident84.8Confident41 Ų4137.4 Ų37.421%0.2120%0.203CC..Hα-helixtrans-65.8-46-179.9-71.1168.4000110.8S9 D10 K11 M16 N17 V509S9-I13 VanDerWaalsContact O-CG1 3.29Å; S9-I13 WeakPolarHBondContact O-CG1 3.22Å; S9-I13 PolarHBondContact O-N 3.47Å; D10-I13 PolarHBondContact O-N 3.22Å; K11-I13 VanDerWaalsContact C-N 3.32Å; K11-I13 PolarHBondContact O-N 3.21Å; I13-M16 PolarHBondContact O-N 3.39Å; I13-N17 WeakPolarHBondContact O-CB 3.47Å; I13-N17 PolarHBondContact O-N 3.1Å; I13-V509 HydrophobicContact CB-CG1 4.32Å; I13-V509 HydrophobicContact CD1-CG1 4.33Å; I13-V509 HydrophobicContact CG1-CG1 4.04Å; I13-V509 HydrophobicContact CG2-CG1 3.46Å; I13-V509 VanDerWaalsContact CG2-CG1 3.46Å
14S85.1Confident85.5Confident30 Ų3036.7 Ų36.721%0.2120%0.197CC..Hα-helixtrans-57.2-50.5175.4156.40000111.4D10 K11 M16 N17 E18 E775D10-S14 PolarHBondContact O-N 3.43Å; K11-S14 PolarHBondContact O-N 2.83Å; S14-M16 VanDerWaalsContact C-N 3.34Å; S14-M16 PolarHBondContact O-N 3.34Å; S14-N17 WeakPolarHBondContact O-CB 3.2Å; S14-N17 PolarHBondContact O-N 2.61Å; S14-N17 VanDerWaalsContact O-N 3.11Å; S14-E18 PolarHBondContact O-N 3.2Å; S14-E775 PolarHBondContact OG-OE1 3.03Å
15I87.5Confident86Confident7 Ų734.9 Ų34.94%0.03618%0.184CC..Hα-helixtrans-57.9-45.2177-66.8167.2000111.5K11 N17 E18 I19 L38 V39 A42K11-I15 HydrophobicContact CG-CD1 3.99Å; K11-I15 VanDerWaalsContact O-CG1 3.31Å; K11-I15 WeakPolarHBondContact O-CG1 3.49Å; K11-I15 PolarHBondContact O-N 3.15Å; K11-I15 VanDerWaalsContact O-N 3.1Å; I15-N17 PolarHBondContact O-N 3.02Å; I15-E18 PolarHBondContact O-N 2.77Å; I15-I19 HydrophobicContact CG2-CD1 3.66Å; I15-I19 HydrophobicContact CG2-CG1 4.48Å; I15-I19 WeakPolarHBondContact O-CD1 3.4Å; I15-I19 VanDerWaalsContact O-CG1 3.27Å; I15-I19 WeakPolarHBondContact O-CG1 3.44Å; I15-I19 PolarHBondContact O-N 3.16Å; I15-L38 HydrophobicContact CG2-CD2 3.82Å; I15-L38 HydrophobicContact CG2-CG 4.13Å; I15-V39 HydrophobicContact CG2-CG2 3.96Å; I15-A42 HydrophobicContact CD1-CB 4.41Å
16M88.4Confident86.5Confident0 Ų034.6 Ų34.60%018%0.183CC..Hα-helixtrans-62.7-42.2177.3-79.7-175.95700111.9R12 I13 S14 I19 L20 V39 F489R12-M16 HydrophobicContact CG-SD 4.4Å; R12-M16 PolarHBondContact NH1-SD 3.08Å; R12-M16 WeakPolarHBondContact O-CB 3.31Å; R12-M16 WeakPolarHBondContact O-CG 3.31Å; R12-M16 PolarHBondContact O-N 3.07Å; I13-M16 PolarHBondContact O-N 3.39Å; S14-M16 VanDerWaalsContact C-N 3.34Å; S14-M16 PolarHBondContact O-N 3.34Å; M16-I19 PolarHBondContact O-N 3.36Å; M16-L20 WeakPolarHBondContact O-CB 3.39Å; M16-L20 WeakPolarHBondContact O-CG 3.41Å; M16-L20 PolarHBondContact O-N 3.46Å; M16-V39 HydrophobicContact CG-CG1 3.91Å; M16-V39 HydrophobicContact CG-CG2 3.95Å; M16-V39 HydrophobicContact SD-CG1 4.07Å; M16-F489 HydrophobicContact CE-CD2 3.85Å; M16-F489 HydrophobicContact CE-CE2 4.06Å; M16-F489 HydrophobicContact CG-CD2 4.48Å; M16-F489 HydrophobicContact CG-CE2 3.99Å; M16-F489 HydrophobicContact SD-CD2 4.35Å; M16-F489 HydrophobicContact SD-CE2 4.43Å
17N85.1Confident87.2Confident72 Ų7233.5 Ų33.539%0.38517%0.173SC..Hα-helixtrans-62.9-43.5179.1-167.829.8000111.3I13 S14 I15 L20 N21I13-N17 WeakPolarHBondContact O-CB 3.47Å; I13-N17 PolarHBondContact O-N 3.1Å; S14-N17 WeakPolarHBondContact O-CB 3.2Å; S14-N17 PolarHBondContact O-N 2.61Å; S14-N17 VanDerWaalsContact O-N 3.11Å; I15-N17 PolarHBondContact O-N 3.02Å; N17-L20 PolarHBondContact O-N 2.9Å; N17-N21 WeakPolarHBondContact O-CB 3.47Å; N17-N21 PolarHBondContact O-N 3.03Å; N17-N21 PolarHBondContact O-ND2 3.44Å; N17-N21 PolarHBondContact OD1-ND2 2.75Å
18E85.1Confident87.6Confident24 Ų2431.9 Ų31.911%0.11216%0.158CC..Hα-helixtrans-61.5-45.3176.8-167.6174.1-146.100111.9S14 I15 A22 F730 L731 G776S14-E18 PolarHBondContact O-N 3.2Å; I15-E18 PolarHBondContact O-N 2.77Å; E18-A22 VanDerWaalsContact O-CB 3.3Å; E18-A22 WeakPolarHBondContact O-CB 3.22Å; E18-A22 PolarHBondContact O-N 3.28Å; E18-F730 HydrophobicContact CG-CD1 4.02Å; E18-F730 VanDerWaalsContact OE1-CA 3.26Å; E18-F730 WeakPolarHBondContact OE1-CA 3.32Å; E18-L731 VanDerWaalsContact CD-N 3.33Å; E18-L731 PolarHBondContact OE1-N 3.48Å; E18-L731 WeakPolarHBondContact OE2-CB 3.32Å; E18-L731 PolarHBondContact OE2-N 3.41Å; E18-G776 PolarHBondContact OE1-N 3.23Å; E18-G776 VanDerWaalsContact OE1-N 3.11Å
19I89.3Confident87.9Confident4 Ų429.2 Ų29.22%0.02115%0.146CC..Hα-helixtrans-61.7-46.7176.8-70.2162.8000111.5I15 M16 A22 A23 I26 F35 V39 F489 I493I15-I19 HydrophobicContact CG2-CD1 3.66Å; I15-I19 HydrophobicContact CG2-CG1 4.48Å; I15-I19 WeakPolarHBondContact O-CD1 3.4Å; I15-I19 VanDerWaalsContact O-CG1 3.27Å; I15-I19 WeakPolarHBondContact O-CG1 3.44Å; I15-I19 PolarHBondContact O-N 3.16Å; M16-I19 PolarHBondContact O-N 3.36Å; I19-A22 CarbonylContact O-C 3.26Å; I19-A22 PolarHBondContact O-N 3.24Å; I19-A23 PolarHBondContact O-N 3.02Å; I19-I26 HydrophobicContact CB-CD1 4.1Å; I19-I26 HydrophobicContact CG1-CD1 4.27Å; I19-I26 HydrophobicContact CG2-CD1 3.69Å; I19-I26 WeakPolarHBondContact O-CD1 3.48Å; I19-F35 HydrophobicContact CD1-CB 3.84Å; I19-F35 HydrophobicContact CD1-CD1 3.74Å; I19-F35 HydrophobicContact CD1-CG 4.15Å; I19-F35 HydrophobicContact CG1-CB 4.1Å; I19-F35 HydrophobicContact CG1-CD1 3.55Å; I19-F35 HydrophobicContact CG1-CE1 4.25Å; I19-F35 HydrophobicContact CG1-CG 3.98Å; I19-F35 HydrophobicContact CG2-CB 4.48Å; I19-V39 HydrophobicContact CD1-CG2 3.46Å; I19-V39 VanDerWaalsContact CD1-CG2 3.46Å; I19-F489 HydrophobicContact CD1-CZ 4.31Å; I19-F489 HydrophobicContact CG2-CZ 4.17Å; I19-I493 HydrophobicContact CG2-CD1 4.47Å
20L87.1Confident88.4Confident7 Ų728.5 Ų28.54%0.03714%0.142CC..Hα-helixtrans-69.1-37.1-175.8-65.3172.9000111.2M16 N17 A22 A23 V492 F500 I505M16-L20 WeakPolarHBondContact O-CB 3.39Å; M16-L20 WeakPolarHBondContact O-CG 3.41Å; M16-L20 PolarHBondContact O-N 3.46Å; N17-L20 PolarHBondContact O-N 2.9Å; L20-A22 VanDerWaalsContact C-N 3.3Å; L20-A22 PolarHBondContact O-N 2.92Å; L20-A23 WeakPolarHBondContact O-CB 3.41Å; L20-A23 PolarHBondContact O-N 3.22Å; L20-V492 HydrophobicContact CD2-CG1 3.73Å; L20-F500 HydrophobicContact CD2-CD1 4.26Å; L20-F500 HydrophobicContact CD2-CE1 3.59Å; L20-I505 HydrophobicContact CB-CB 4.47Å; L20-I505 HydrophobicContact CB-CD1 3.83Å; L20-I505 HydrophobicContact CB-CG1 3.92Å; L20-I505 HydrophobicContact CB-CG2 3.73Å; L20-I505 HydrophobicContact CD1-CG2 3.63Å; L20-I505 HydrophobicContact CG-CG2 4.31Å
21N82.1Confident88.8Confident88 Ų8825.4 Ų25.447%0.47112%0.124SC..Hα-helixtrans-67.5-29.8173.4-74.2-52.5000112.6N17 I505N17-N21 WeakPolarHBondContact O-CB 3.47Å; N17-N21 PolarHBondContact O-N 3.03Å; N17-N21 PolarHBondContact O-ND2 3.44Å; N17-N21 PolarHBondContact OD1-ND2 2.75Å; N21-I505 WeakPolarHBondContact OD1-CD1 3.48Å
22A87.4Confident89.1Confident2 Ų221.3 Ų21.32%0.01711%0.106CC..THydrogen-bonded Turntrans-98.914.5-179.700000113.9E18 I19 L20 R24 V25 I26 I728 F730E18-A22 VanDerWaalsContact O-CB 3.3Å; E18-A22 WeakPolarHBondContact O-CB 3.22Å; E18-A22 PolarHBondContact O-N 3.28Å; I19-A22 CarbonylContact O-C 3.26Å; I19-A22 PolarHBondContact O-N 3.24Å; L20-A22 VanDerWaalsContact C-N 3.3Å; L20-A22 PolarHBondContact O-N 2.92Å; A22-R24 PolarHBondContact O-N 3.15Å; A22-R24 VanDerWaalsContact O-N 3.11Å; A22-V25 PolarHBondContact O-N 3.45Å; A22-I26 HydrophobicContact CB-CD1 4.27Å; A22-I26 HydrophobicContact CB-CG1 4.38Å; A22-I26 WeakPolarHBondContact O-CG1 3.43Å; A22-I26 PolarHBondContact O-N 3Å; A22-I728 HydrophobicContact CB-CD1 3.71Å; A22-I728 HydrophobicContact CB-CG2 4.04Å; A22-F730 HydrophobicContact CB-CE1 3.54Å; A22-F730 HydrophobicContact CB-CZ 3.79Å
23A89.4Confident89.2Confident8 Ų827.5 Ų27.57%0.06613%0.131CC..Hα-helixtrans-54.7-37.2-170.600000113.4I19 L20 K27 I497 F500I19-A23 PolarHBondContact O-N 3.02Å; L20-A23 WeakPolarHBondContact O-CB 3.41Å; L20-A23 PolarHBondContact O-N 3.22Å; A23-K27 WeakPolarHBondContact O-CB 3.49Å; A23-K27 VanDerWaalsContact O-CG 3.25Å; A23-K27 WeakPolarHBondContact O-CG 3.4Å; A23-K27 PolarHBondContact O-N 3.08Å; A23-I497 HydrophobicContact CB-CD1 4.43Å; A23-F500 HydrophobicContact CB-CD1 3.74Å; A23-F500 HydrophobicContact CB-CD2 4.15Å; A23-F500 HydrophobicContact CB-CE1 3.71Å; A23-F500 HydrophobicContact CB-CE2 4.13Å; A23-F500 HydrophobicContact CB-CG 3.95Å; A23-F500 HydrophobicContact CB-CZ 3.9Å
24R89.4Confident89.4Confident114 Ų11426.7 Ų26.743%0.4313%0.128SC..Hα-helixtrans-60.1-50.7176.9-170.2-179.7-63.81751.3111.8A22 K27 M28 I497 L694A22-R24 PolarHBondContact O-N 3.15Å; A22-R24 VanDerWaalsContact O-N 3.11Å; R24-K27 PolarHBondContact O-N 3.39Å; R24-M28 HydrophobicContact CG-CE 3.79Å; R24-M28 HydrophobicContact CG-SD 4.15Å; R24-M28 VanDerWaalsContact O-CG 3.29Å; R24-M28 WeakPolarHBondContact O-CG 3.47Å; R24-M28 PolarHBondContact O-N 3.26Å; R24-I497 HydrophobicContact CB-CD1 3.82Å; R24-I497 HydrophobicContact CG-CD1 4.42Å; R24-L694 HydrophobicContact CG-CD1 4.13Å
25V90.9Very high89.7Confident13 Ų1326 Ų268%0.07912%0.121CC..Hα-helixtrans-67.5-42.1-178.5176.20000110.7A22 K27 M28 Y29 P724 I728A22-V25 PolarHBondContact O-N 3.45Å; V25-K27 VanDerWaalsContact C-N 3.32Å; V25-K27 PolarHBondContact O-N 3.01Å; V25-M28 PolarHBondContact O-N 3.39Å; V25-Y29 HydrophobicContact CG1-CD2 3.52Å; V25-Y29 HydrophobicContact CG1-CE2 3.35Å; V25-Y29 VanDerWaalsContact O-CD2 3.28Å; V25-Y29 WeakPolarHBondContact O-CD2 3.26Å; V25-Y29 PolarHBondContact O-N 3.49Å; V25-P724 HydrophobicContact CG2-CB 4.31Å; V25-P724 HydrophobicContact CG2-CG 4.49Å; V25-I728 HydrophobicContact CG2-CD1 4.03Å
26I92.7Very high89.8Confident2 Ų227.6 Ų27.61%0.0113%0.129CC..Hα-helixtrans-58.2-45.2176.2-68.6175.4000111I19 A22 Y29 A30 W31 E32 F35 F730I19-I26 HydrophobicContact CB-CD1 4.1Å; I19-I26 HydrophobicContact CG1-CD1 4.27Å; I19-I26 HydrophobicContact CG2-CD1 3.69Å; I19-I26 WeakPolarHBondContact O-CD1 3.48Å; A22-I26 HydrophobicContact CB-CD1 4.27Å; A22-I26 HydrophobicContact CB-CG1 4.38Å; A22-I26 WeakPolarHBondContact O-CG1 3.43Å; A22-I26 PolarHBondContact O-N 3Å; I26-Y29 PolarHBondContact O-N 2.94Å; I26-A30 PolarHBondContact O-N 3.41Å; I26-A30 VanDerWaalsContact O-N 3.15Å; I26-W31 HydrophobicContact CG2-CB 4.06Å; I26-W31 PolarHBondContact O-N 3.04Å; I26-E32 HydrophobicContact CG2-CG 4.26Å; I26-F35 HydrophobicContact CD1-CD2 3.75Å; I26-F35 HydrophobicContact CD1-CE2 3.98Å; I26-F35 HydrophobicContact CD1-CG 4.14Å; I26-F35 HydrophobicContact CG1-CD2 3.92Å; I26-F35 HydrophobicContact CG1-CE2 3.85Å; I26-F35 HydrophobicContact CG2-CD2 3.91Å; I26-F35 HydrophobicContact CG2-CE2 4.49Å; I26-F730 HydrophobicContact CD1-CE1 3.82Å; I26-F730 HydrophobicContact CD1-CZ 4Å; I26-F730 HydrophobicContact CG1-CE1 3.99Å; I26-F730 HydrophobicContact CG1-CZ 3.63Å
27K92.9Very high89.9Confident4 Ų430 Ų302%0.01714%0.141CC..Hα-helixtrans-64.3-46.9177.3-73.6171.2-178.1-70.10111.5A23 R24 V25 Y29 A30 E32 I493 A495 E625 L694 R717A23-K27 WeakPolarHBondContact O-CB 3.49Å; A23-K27 VanDerWaalsContact O-CG 3.25Å; A23-K27 WeakPolarHBondContact O-CG 3.4Å; A23-K27 PolarHBondContact O-N 3.08Å; R24-K27 PolarHBondContact O-N 3.39Å; V25-K27 VanDerWaalsContact C-N 3.32Å; V25-K27 PolarHBondContact O-N 3.01Å; K27-Y29 VanDerWaalsContact C-N 3.26Å; K27-Y29 PolarHBondContact O-N 3.01Å; K27-A30 PolarHBondContact O-N 3.25Å; K27-E32 HydrophobicContact CG-CG 4.46Å; K27-I493 PolarHBondContact NZ-O 3.24Å; K27-A495 VanDerWaalsContact CE-O 3.28Å; K27-A495 WeakPolarHBondContact CE-O 3.34Å; K27-A495 PolarHBondContact NZ-O 2.78Å; K27-E625 WeakPolarHBondContact CD-OE1 2.84Å; K27-E625 VanDerWaalsContact CE-OE1 3.27Å; K27-E625 WeakPolarHBondContact CE-OE1 3.35Å; K27-E625 VanDerWaalsContact NZ-CD 3.32Å; K27-E625 IonicContact NZ-OE1 3.14Å; K27-E625 PolarHBondContact NZ-OE1 3.03Å; K27-E625 IonicContact NZ-OE2 3.87Å; K27-L694 HydrophobicContact CB-CD2 3.79Å; K27-L694 HydrophobicContact CD-CD2 4.42Å; K27-R717 VanDerWaalsContact O-CD 3.3Å; K27-R717 WeakPolarHBondContact O-CD 3.46Å
28M92.4Very high90.1Very high7 Ų729.9 Ų29.93%0.03414%0.14CC..Hα-helixtrans-59.9-35.6179.3-68.8166.4166.100112.8R24 V25 A30 I688 F692 L694 I722R24-M28 HydrophobicContact CG-CE 3.79Å; R24-M28 HydrophobicContact CG-SD 4.15Å; R24-M28 VanDerWaalsContact O-CG 3.29Å; R24-M28 WeakPolarHBondContact O-CG 3.47Å; R24-M28 PolarHBondContact O-N 3.26Å; V25-M28 PolarHBondContact O-N 3.39Å; M28-A30 VanDerWaalsContact C-N 3.35Å; M28-I688 HydrophobicContact CE-CG2 3.73Å; M28-F692 HydrophobicContact CB-CD1 4.1Å; M28-F692 HydrophobicContact CB-CE1 4.17Å; M28-F692 HydrophobicContact CG-CD1 4.16Å; M28-F692 HydrophobicContact CG-CG 4.19Å; M28-L694 HydrophobicContact CE-CD1 3.54Å; M28-L694 HydrophobicContact CG-CD1 4.07Å; M28-L694 HydrophobicContact CG-CD2 4.46Å; M28-I722 HydrophobicContact CB-CG2 4.02Å; M28-I722 HydrophobicContact CE-CD1 4.18Å; M28-I722 HydrophobicContact SD-CD1 3.68Å
29Y92.7Very high90.4Very high4 Ų428.9 Ų28.92%0.01614%0.135CC..THydrogen-bonded Turntrans-81.7-6.6174.9-72.2-55.3000114.8V25 I26 K27 W31 I722 P724V25-Y29 HydrophobicContact CG1-CD2 3.52Å; V25-Y29 HydrophobicContact CG1-CE2 3.35Å; V25-Y29 VanDerWaalsContact O-CD2 3.28Å; V25-Y29 WeakPolarHBondContact O-CD2 3.26Å; V25-Y29 PolarHBondContact O-N 3.49Å; I26-Y29 PolarHBondContact O-N 2.94Å; K27-Y29 VanDerWaalsContact C-N 3.26Å; K27-Y29 PolarHBondContact O-N 3.01Å; Y29-W31 VanDerWaalsContact C-N 3.32Å; Y29-W31 HydrophobicContact CD2-CD2 4.27Å; Y29-W31 AromaticContact CD2-CE3 3.99Å; Y29-W31 HydrophobicContact CD2-CE3 3.99Å; Y29-W31 HydrophobicContact CD2-CH2 4.28Å; Y29-W31 HydrophobicContact CD2-CZ2 4.48Å; Y29-W31 HydrophobicContact CD2-CZ3 4.01Å; Y29-W31 HydrophobicContact CE2-CZ3 4.48Å; Y29-W31 HydrophobicContact CG-CD2 4.13Å; Y29-W31 HydrophobicContact CG-CE3 4.32Å; Y29-W31 HydrophobicContact CG-CZ2 4.27Å; Y29-W31 VanDerWaalsContact O-CD1 3.24Å; Y29-I722 HydrophobicContact CD1-CG2 4.31Å; Y29-I722 HydrophobicContact CE1-CG2 3.89Å; Y29-I722 PolarHBondContact OH-O 2.77Å; Y29-I722 VanDerWaalsContact OH-O 3.06Å; Y29-P724 WeakPolarHBondContact OH-CD 3.16Å
30A93.4Very high90.5Very high0 Ų035 Ų350%016%0.158CC..THydrogen-bonded Turntrans58.438.8-170.400000113.5I26 K27 M28 E32 R717 K718 F741I26-A30 PolarHBondContact O-N 3.41Å; I26-A30 VanDerWaalsContact O-N 3.15Å; K27-A30 PolarHBondContact O-N 3.25Å; M28-A30 VanDerWaalsContact C-N 3.35Å; A30-E32 WeakPolarHBondContact CA-OE2 3.4Å; A30-R717 HydrophobicContact CB-CB 4.08Å; A30-K718 HydrophobicContact CB-CG 3.89Å; A30-F741 WeakPolarHBondContact O-CZ 3.49Å
31W92.6Very high90.7Very high12 Ų1238.7 Ų38.75%0.04518%0.178CC..  trans-94.110.7-176.2-72-3000114.1I26 Y29 Y33 P34 F35 F730 N737 P740 F741 R792I26-W31 HydrophobicContact CG2-CB 4.06Å; I26-W31 PolarHBondContact O-N 3.04Å; Y29-W31 VanDerWaalsContact C-N 3.32Å; Y29-W31 HydrophobicContact CD2-CD2 4.27Å; Y29-W31 AromaticContact CD2-CE3 3.99Å; Y29-W31 HydrophobicContact CD2-CE3 3.99Å; Y29-W31 HydrophobicContact CD2-CH2 4.28Å; Y29-W31 HydrophobicContact CD2-CZ2 4.48Å; Y29-W31 HydrophobicContact CD2-CZ3 4.01Å; Y29-W31 HydrophobicContact CE2-CZ3 4.48Å; Y29-W31 HydrophobicContact CG-CD2 4.13Å; Y29-W31 HydrophobicContact CG-CE3 4.32Å; Y29-W31 HydrophobicContact CG-CZ2 4.27Å; Y29-W31 VanDerWaalsContact O-CD1 3.24Å; W31-Y33 VanDerWaalsContact C-N 3.29Å; W31-Y33 PolarHBondContact O-N 3.4Å; W31-P34 VanDerWaalsContact O-CD 3.29Å; W31-P34 WeakPolarHBondContact O-CD 3.39Å; W31-F35 HydrophobicContact CB-CD2 3.89Å; W31-F35 HydrophobicContact CB-CE2 3.81Å; W31-F35 HydrophobicContact CD2-CE2 4.47Å; W31-F35 AromaticContact CE3-CE2 3.93Å; W31-F35 HydrophobicContact CE3-CE2 3.93Å; W31-F35 HydrophobicContact CE3-CZ 4.48Å; W31-F35 HydrophobicContact CG-CE2 4.5Å; W31-F35 WeakPolarHBondContact O-CD2 3.43Å; W31-F35 PolarHBondContact O-N 2.93Å; W31-F730 HydrophobicContact CE3-CE2 4.05Å; W31-F730 HydrophobicContact CZ3-CD2 4.34Å; W31-F730 AromaticContact CZ3-CE2 3.88Å; W31-F730 HydrophobicContact CZ3-CE2 3.88Å; W31-N737 WeakPolarHBondContact CH2-O 3.45Å; W31-P740 HydrophobicContact CD2-CG 3.68Å; W31-P740 VanDerWaalsContact CE2-CG 3.46Å; W31-P740 HydrophobicContact CE3-CG 3.99Å; W31-P740 HydrophobicContact CG-CG 4.26Å; W31-P740 HydrophobicContact CH2-CG 3.82Å; W31-P740 VanDerWaalsContact CZ2-CD 3.49Å; W31-P740 HydrophobicContact CZ2-CG 3.55Å; W31-P740 HydrophobicContact CZ3-CG 4.05Å; W31-F741 AromaticContact CD1-CE2 3.6Å; W31-R792 HydrophobicContact CH2-CG 4.45Å
32E92.2Very high91.1Very high7 Ų735 Ų353%0.03316%0.159CC..Hα-helixtrans-57.9-39.2-175.8-63.292.1143.400112.5I26 K27 A30 M36 I493 H714 R717I26-E32 HydrophobicContact CG2-CG 4.26Å; K27-E32 HydrophobicContact CG-CG 4.46Å; A30-E32 WeakPolarHBondContact CA-OE2 3.4Å; E32-M36 VanDerWaalsContact O-CB 3.28Å; E32-M36 WeakPolarHBondContact O-CB 3.37Å; E32-M36 PolarHBondContact O-N 2.95Å; E32-I493 HydrophobicContact CB-CD1 4.05Å; E32-I493 HydrophobicContact CB-CG1 4.06Å; E32-I493 HydrophobicContact CG-CG1 4.08Å; E32-I493 WeakPolarHBondContact O-CD1 3.5Å; E32-H714 IonicContact OE2-NE2 2.98Å; E32-H714 PolarHBondContact OE2-NE2 3.38Å; E32-R717 IonicContact OE1-NH1 3.59Å; E32-R717 PolarHBondContact OE1-NH1 3.24Å
33Y91.1Very high91.2Very high132 Ų13234.9 Ų34.952%0.51816%0.159SC..Hα-helixtrans-69.4-51-176.7179.2-90000113.8W31 F35 M36 M37W31-Y33 VanDerWaalsContact C-N 3.29Å; W31-Y33 PolarHBondContact O-N 3.4Å; Y33-F35 VanDerWaalsContact C-N 3.31Å; Y33-F35 PolarHBondContact O-N 3.41Å; Y33-M36 HydrophobicContact CD2-CE 3.65Å; Y33-M36 HydrophobicContact CE2-CE 3.99Å; Y33-M36 WeakPolarHBondContact O-CB 3.5Å; Y33-M36 PolarHBondContact O-N 3.46Å; Y33-M37 HydrophobicContact CD1-CG 4.36Å; Y33-M37 HydrophobicContact CE1-CG 3.9Å; Y33-M37 HydrophobicContact CE2-CG 4.37Å; Y33-M37 PolarHBondContact O-N 2.96Å
34P90.2Very high91.3Very high23 Ų2336.7 Ų36.715%0.14917%0.173CC..Hα-helixtrans-54.4-44.4174.4-28.834.2000113.2W31 M37 L38 P740 F741W31-P34 VanDerWaalsContact O-CD 3.29Å; W31-P34 WeakPolarHBondContact O-CD 3.39Å; P34-M37 PolarHBondContact O-N 3.35Å; P34-L38 WeakPolarHBondContact O-CB 3.38Å; P34-L38 PolarHBondContact O-N 3.09Å; P34-P740 HydrophobicContact CB-CB 4.1Å; P34-P740 HydrophobicContact CG-CB 4.24Å; P34-F741 VanDerWaalsContact CD-CZ 3.5Å; P34-F741 HydrophobicContact CG-CD1 3.6Å; P34-F741 HydrophobicContact CG-CD2 4.31Å; P34-F741 HydrophobicContact CG-CE1 3.26Å; P34-F741 HydrophobicContact CG-CE2 4.03Å; P34-F741 HydrophobicContact CG-CG 4.11Å; P34-F741 HydrophobicContact CG-CZ 3.49Å; P34-F741 VanDerWaalsContact CG-CZ 3.49Å
35F90.9Very high91.3Very high16 Ų1634.9 Ų34.97%0.0717%0.17CC..Hα-helixtrans-69.3-34.5178.8-76.2-65.5000112.9I19 I26 W31 Y33 M37 L38 V39 I493 F730I19-F35 HydrophobicContact CD1-CB 3.84Å; I19-F35 HydrophobicContact CD1-CD1 3.74Å; I19-F35 HydrophobicContact CD1-CG 4.15Å; I19-F35 HydrophobicContact CG1-CB 4.1Å; I19-F35 HydrophobicContact CG1-CD1 3.55Å; I19-F35 HydrophobicContact CG1-CE1 4.25Å; I19-F35 HydrophobicContact CG1-CG 3.98Å; I19-F35 HydrophobicContact CG2-CB 4.48Å; I26-F35 HydrophobicContact CD1-CD2 3.75Å; I26-F35 HydrophobicContact CD1-CE2 3.98Å; I26-F35 HydrophobicContact CD1-CG 4.14Å; I26-F35 HydrophobicContact CG1-CD2 3.92Å; I26-F35 HydrophobicContact CG1-CE2 3.85Å; I26-F35 HydrophobicContact CG2-CD2 3.91Å; I26-F35 HydrophobicContact CG2-CE2 4.49Å; W31-F35 HydrophobicContact CB-CD2 3.89Å; W31-F35 HydrophobicContact CB-CE2 3.81Å; W31-F35 HydrophobicContact CD2-CE2 4.47Å; W31-F35 AromaticContact CE3-CE2 3.93Å; W31-F35 HydrophobicContact CE3-CE2 3.93Å; W31-F35 HydrophobicContact CE3-CZ 4.48Å; W31-F35 HydrophobicContact CG-CE2 4.5Å; W31-F35 WeakPolarHBondContact O-CD2 3.43Å; W31-F35 PolarHBondContact O-N 2.93Å; Y33-F35 VanDerWaalsContact C-N 3.31Å; Y33-F35 PolarHBondContact O-N 3.41Å; F35-M37 VanDerWaalsContact C-N 3.35Å; F35-L38 HydrophobicContact CD1-CD2 4.16Å; F35-L38 HydrophobicContact CE1-CD2 4.46Å; F35-L38 PolarHBondContact O-N 3.38Å; F35-V39 WeakPolarHBondContact O-CG2 3.3Å; F35-V39 PolarHBondContact O-N 3.44Å; F35-V39 VanDerWaalsContact O-N 3.07Å; F35-I493 HydrophobicContact CB-CD1 4.43Å; F35-F730 HydrophobicContact CE1-CB 4.14Å; F35-F730 AromaticContact CE1-CD1 3.65Å; F35-F730 HydrophobicContact CE1-CD1 3.65Å; F35-F730 HydrophobicContact CE1-CD2 4.28Å; F35-F730 HydrophobicContact CE1-CE1 4.1Å; F35-F730 AromaticContact CE1-CG 3.75Å; F35-F730 HydrophobicContact CE1-CG 3.75Å; F35-F730 HydrophobicContact CE2-CD2 4.38Å; F35-F730 HydrophobicContact CE2-CE1 4.3Å; F35-F730 HydrophobicContact CE2-CE2 4.13Å; F35-F730 HydrophobicContact CE2-CZ 4.09Å; F35-F730 HydrophobicContact CZ-CB 4.18Å; F35-F730 AromaticContact CZ-CD1 3.57Å; F35-F730 HydrophobicContact CZ-CD1 3.57Å; F35-F730 AromaticContact CZ-CD2 3.51Å; F35-F730 HydrophobicContact CZ-CD2 3.51Å; F35-F730 AromaticContact CZ-CE1 3.73Å; F35-F730 HydrophobicContact CZ-CE1 3.73Å; F35-F730 AromaticContact CZ-CE2 3.68Å; F35-F730 HydrophobicContact CZ-CE2 3.68Å; F35-F730 AromaticContact CZ-CG 3.45Å; F35-F730 HydrophobicContact CZ-CG 3.45Å; F35-F730 VanDerWaalsContact CZ-CG 3.45Å; F35-F730 AromaticContact CZ-CZ 3.8Å; F35-F730 HydrophobicContact CZ-CZ 3.8Å
36M91Very high91.2Very high41 Ų4134.4 Ų34.420%0.20217%0.167CC..Hα-helixtrans-61.6-42.4170.8-177.1-176.365.100112.1E32 Y33 R40 F489 H490E32-M36 VanDerWaalsContact O-CB 3.28Å; E32-M36 WeakPolarHBondContact O-CB 3.37Å; E32-M36 PolarHBondContact O-N 2.95Å; Y33-M36 HydrophobicContact CD2-CE 3.65Å; Y33-M36 HydrophobicContact CE2-CE 3.99Å; Y33-M36 WeakPolarHBondContact O-CB 3.5Å; Y33-M36 PolarHBondContact O-N 3.46Å; M36-R40 WeakPolarHBondContact O-CB 3.46Å; M36-R40 PolarHBondContact O-N 2.94Å; M36-F489 HydrophobicContact CB-CE1 4.46Å; M36-F489 HydrophobicContact CG-CD1 4.39Å; M36-H490 HydrophobicContact SD-CB 4.21Å; M36-H490 PolarHBondContact SD-ND1 3.33Å
37M90.4Very high90.9Very high51 Ų5134.5 Ų34.525%0.25117%0.167SC..Hα-helixtrans-66.5-42.2176-71.8-59.8-62.100111.6Y33 P34 F35 V39 R40 D41Y33-M37 HydrophobicContact CD1-CG 4.36Å; Y33-M37 HydrophobicContact CE1-CG 3.9Å; Y33-M37 HydrophobicContact CE2-CG 4.37Å; Y33-M37 PolarHBondContact O-N 2.96Å; P34-M37 PolarHBondContact O-N 3.35Å; F35-M37 VanDerWaalsContact C-N 3.35Å; M37-V39 PolarHBondContact O-N 3.12Å; M37-R40 WeakPolarHBondContact O-CB 3.49Å; M37-R40 PolarHBondContact O-N 3.5Å; M37-R40 VanDerWaalsContact O-N 3.14Å; M37-D41 PolarHBondContact O-N 3.03Å
38L89.8Confident90.7Very high69 Ų6939.3 Ų39.336%0.36119%0.19SC..Hα-helixtrans-57.3-45.9176.8-175.165.1000112.4I15 P34 F35 D41 A42I15-L38 HydrophobicContact CG2-CD2 3.82Å; I15-L38 HydrophobicContact CG2-CG 4.13Å; P34-L38 WeakPolarHBondContact O-CB 3.38Å; P34-L38 PolarHBondContact O-N 3.09Å; F35-L38 HydrophobicContact CD1-CD2 4.16Å; F35-L38 HydrophobicContact CE1-CD2 4.46Å; F35-L38 PolarHBondContact O-N 3.38Å; L38-D41 PolarHBondContact O-N 3.47Å; L38-A42 WeakPolarHBondContact O-CB 2.94Å; L38-A42 PolarHBondContact O-N 3.22Å
39V90.8Very high90.4Very high2 Ų241.4 Ų41.41%0.01220%0.199CC..Hα-helixtrans-68.1-38.2177.2172.50000111.6I15 M16 I19 F35 M37 A42 R43 F489I15-V39 HydrophobicContact CG2-CG2 3.96Å; M16-V39 HydrophobicContact CG-CG1 3.91Å; M16-V39 HydrophobicContact CG-CG2 3.95Å; M16-V39 HydrophobicContact SD-CG1 4.07Å; I19-V39 HydrophobicContact CD1-CG2 3.46Å; I19-V39 VanDerWaalsContact CD1-CG2 3.46Å; F35-V39 WeakPolarHBondContact O-CG2 3.3Å; F35-V39 PolarHBondContact O-N 3.44Å; F35-V39 VanDerWaalsContact O-N 3.07Å; M37-V39 PolarHBondContact O-N 3.12Å; V39-A42 PolarHBondContact O-N 3.24Å; V39-R43 WeakPolarHBondContact O-CB 3.36Å; V39-R43 PolarHBondContact O-N 3.36Å; V39-F489 HydrophobicContact CB-CD1 4.25Å; V39-F489 HydrophobicContact CB-CE1 3.89Å; V39-F489 HydrophobicContact CB-CZ 4.08Å; V39-F489 HydrophobicContact CG1-CD1 4.13Å; V39-F489 HydrophobicContact CG1-CD2 4.27Å; V39-F489 HydrophobicContact CG1-CE1 4.16Å; V39-F489 HydrophobicContact CG1-CE2 4.28Å; V39-F489 HydrophobicContact CG1-CG 4.19Å; V39-F489 HydrophobicContact CG1-CZ 4.22Å; V39-F489 HydrophobicContact CG2-CE1 3.89Å; V39-F489 HydrophobicContact CG2-CE2 4.19Å; V39-F489 HydrophobicContact CG2-CZ 3.61Å
40R91.4Very high90Very high132 Ų13241.4 Ų41.450%0.49820%0.199SC..Hα-helixtrans-62.6-41.9176.2-179.6-178.7172.4175.5-3111.7M36 M37 R43 A44 F482M36-R40 WeakPolarHBondContact O-CB 3.46Å; M36-R40 PolarHBondContact O-N 2.94Å; M37-R40 WeakPolarHBondContact O-CB 3.49Å; M37-R40 PolarHBondContact O-N 3.5Å; M37-R40 VanDerWaalsContact O-N 3.14Å; R40-R43 PolarHBondContact O-N 3.46Å; R40-A44 PolarHBondContact O-N 3.44Å; R40-F482 HydrophobicContact CG-CZ 4.25Å
41D91.2Very high89.7Confident85 Ų8547.6 Ų47.646%0.45522%0.222SC..Hα-helixtrans-69-44.2178.7-70-15.6000111.2M37 L38 R43 A44 E45M37-D41 PolarHBondContact O-N 3.03Å; L38-D41 PolarHBondContact O-N 3.47Å; D41-R43 VanDerWaalsContact C-N 3.26Å; D41-R43 PolarHBondContact O-N 3.49Å; D41-A44 WeakPolarHBondContact O-CB 3.38Å; D41-A44 PolarHBondContact O-N 2.85Å; D41-E45 PolarHBondContact O-N 2.7Å
42A90.1Very high89.3Confident10 Ų1053.8 Ų53.88%0.08325%0.246CC..Hα-helixtrans-56.9-41.2172.300000111.8R12 I15 L38 V39 E45 E46R12-A42 HydrophobicContact CB-CB 4.17Å; R12-A42 HydrophobicContact CG-CB 4.23Å; I15-A42 HydrophobicContact CD1-CB 4.41Å; L38-A42 WeakPolarHBondContact O-CB 2.94Å; L38-A42 PolarHBondContact O-N 3.22Å; V39-A42 PolarHBondContact O-N 3.24Å; A42-E45 PolarHBondContact O-N 3.04Å; A42-E46 PolarHBondContact O-N 3.42Å; A42-E46 VanDerWaalsContact O-N 3.14Å
43R90.2Very high88.8Confident1 Ų154.1 Ų54.10%0.00425%0.247CC..Hα-helixtrans-68.4-33.4175.3-17360.6171.2174.3-1.5112.5V39 R40 D41 E46 M47 F482 S516V39-R43 WeakPolarHBondContact O-CB 3.36Å; V39-R43 PolarHBondContact O-N 3.36Å; R40-R43 PolarHBondContact O-N 3.46Å; D41-R43 VanDerWaalsContact C-N 3.26Å; D41-R43 PolarHBondContact O-N 3.49Å; R43-E46 VanDerWaalsContact CD-OE2 3.26Å; R43-E46 WeakPolarHBondContact CD-OE2 3.5Å; R43-E46 IonicContact CZ-OE2 3.13Å; R43-E46 IonicContact NE-OE2 3.23Å; R43-E46 IonicContact NH1-OE1 3.94Å; R43-E46 PolarHBondContact NH1-OE1 2.89Å; R43-E46 IonicContact NH1-OE2 3.33Å; R43-E46 PolarHBondContact NH1-OE2 3.47Å; R43-M47 VanDerWaalsContact O-CB 3.25Å; R43-M47 WeakPolarHBondContact O-CB 3.31Å; R43-M47 PolarHBondContact O-N 2.86Å; R43-F482 HydrophobicContact CB-CE2 4.27Å; R43-F482 HydrophobicContact CG-CD2 3.81Å; R43-F482 HydrophobicContact CG-CE2 3.84Å; R43-S516 PolarHBondContact NH1-OG 3.01Å; R43-S516 PolarHBondContact NH2-OG 3.34Å; R43-S516 VanDerWaalsContact NH2-OG 3.12Å
44A91.1Very high88.4Confident45 Ų4547.9 Ų47.937%0.37222%0.223SC..Hα-helixtrans-67.3-41.4176.400000111.9R40 D41 M47 Q48R40-A44 PolarHBondContact O-N 3.44Å; D41-A44 WeakPolarHBondContact O-CB 3.38Å; D41-A44 PolarHBondContact O-N 2.85Å; A44-M47 PolarHBondContact O-N 2.95Å; A44-Q48 PolarHBondContact O-N 2.87Å
45E90.4Very high88.3Confident77 Ų7750.4 Ų50.436%0.3624%0.235SC..Hα-helixtrans-61.5-45.8173.3-68.5-174.3-174.700111.9K8 D41 A42 M47 Q48 K49K8-E45 HydrophobicContact CD-CB 4.43Å; K8-E45 WeakPolarHBondContact CD-OE2 3.42Å; K8-E45 WeakPolarHBondContact CE-OE2 3.37Å; K8-E45 IonicContact NZ-OE2 3.85Å; K8-E45 PolarHBondContact NZ-OE2 3.34Å; D41-E45 PolarHBondContact O-N 2.7Å; A42-E45 PolarHBondContact O-N 3.04Å; E45-M47 VanDerWaalsContact C-N 3.34Å; E45-M47 PolarHBondContact O-N 3.43Å; E45-Q48 WeakPolarHBondContact O-CB 3.1Å; E45-Q48 PolarHBondContact O-N 2.89Å; E45-K49 PolarHBondContact O-N 3.1Å
46E87.9Confident87.9Confident3 Ų353 Ų531%0.01425%0.254CS..Hα-helixtrans-58.2-47.1174.6-175.2-173.9-176.800110.8L5 K8 S9 R12 A42 R43 Q48 K49 L50L5-E46 HydrophobicContact CD1-CG 3.76Å; K8-E46 HydrophobicContact CB-CB 4.48Å; S9-E46 VanDerWaalsContact OG-CD 3.32Å; S9-E46 PolarHBondContact OG-OE1 3.15Å; R12-E46 WeakPolarHBondContact CD-OE2 3.46Å; R12-E46 IonicContact NE-OE2 3.3Å; R12-E46 PolarHBondContact NE-OE2 3.34Å; A42-E46 PolarHBondContact O-N 3.42Å; A42-E46 VanDerWaalsContact O-N 3.14Å; R43-E46 VanDerWaalsContact CD-OE2 3.26Å; R43-E46 WeakPolarHBondContact CD-OE2 3.5Å; R43-E46 IonicContact CZ-OE2 3.13Å; R43-E46 IonicContact NE-OE2 3.23Å; R43-E46 IonicContact NH1-OE1 3.94Å; R43-E46 PolarHBondContact NH1-OE1 2.89Å; R43-E46 IonicContact NH1-OE2 3.33Å; R43-E46 PolarHBondContact NH1-OE2 3.47Å; E46-Q48 VanDerWaalsContact C-N 3.29Å; E46-Q48 PolarHBondContact O-N 3.3Å; E46-K49 PolarHBondContact O-N 3.01Å; E46-K49 VanDerWaalsContact O-N 3.1Å; E46-L50 HydrophobicContact CG-CD1 4.15Å; E46-L50 PolarHBondContact O-N 3.44Å
47M86.5Confident87.4Confident3 Ų351.7 Ų51.72%0.01525%0.248CC..Hα-helixtrans-62.2-34.5180-172.156.657.100112.3R43 A44 E45 K49 L50 R51 L478 F482R43-M47 VanDerWaalsContact O-CB 3.25Å; R43-M47 WeakPolarHBondContact O-CB 3.31Å; R43-M47 PolarHBondContact O-N 2.86Å; A44-M47 PolarHBondContact O-N 2.95Å; E45-M47 VanDerWaalsContact C-N 3.34Å; E45-M47 PolarHBondContact O-N 3.43Å; M47-K49 VanDerWaalsContact C-N 3.31Å; M47-K49 PolarHBondContact O-N 3.46Å; M47-L50 HydrophobicContact CE-CD1 4.19Å; M47-L50 PolarHBondContact O-N 3.22Å; M47-L50 HydrophobicContact SD-CB 4.34Å; M47-R51 HydrophobicContact CG-CG 4.47Å; M47-R51 WeakPolarHBondContact O-CB 3.42Å; M47-R51 VanDerWaalsContact O-CG 3.25Å; M47-R51 WeakPolarHBondContact O-CG 3.21Å; M47-R51 PolarHBondContact O-N 3.21Å; M47-R51 HydrophobicContact SD-CG 4.5Å; M47-L478 HydrophobicContact CE-CD2 4.4Å; M47-L478 HydrophobicContact SD-CB 3.83Å; M47-L478 HydrophobicContact SD-CD1 4.23Å; M47-L478 HydrophobicContact SD-CD2 3.95Å; M47-L478 HydrophobicContact SD-CG 4.23Å; M47-F482 HydrophobicContact CE-CB 4.11Å; M47-F482 HydrophobicContact CE-CD2 4.4Å
48Q87.8Confident87.1Confident106 Ų10649.3 Ų49.350%0.49524%0.236SC..Hα-helixtrans-62.3-39.4175.7-164.9-169.827.200111.7A44 E45 E46A44-Q48 PolarHBondContact O-N 2.87Å; E45-Q48 WeakPolarHBondContact O-CB 3.1Å; E45-Q48 PolarHBondContact O-N 2.89Å; E46-Q48 VanDerWaalsContact C-N 3.29Å; E46-Q48 PolarHBondContact O-N 3.3Å
49K86Confident86.9Confident50 Ų5049 Ų4922%0.21724%0.237CC..Hα-helixtrans-72.2-42.6175.1-59.9-61.3-177.7179.40111.4L5 E45 E46 M47 R51 R52 H53L5-K49 HydrophobicContact CB-CB 4.39Å; L5-K49 HydrophobicContact CD1-CB 4.23Å; E45-K49 PolarHBondContact O-N 3.1Å; E46-K49 PolarHBondContact O-N 3.01Å; E46-K49 VanDerWaalsContact O-N 3.1Å; M47-K49 VanDerWaalsContact C-N 3.31Å; M47-K49 PolarHBondContact O-N 3.46Å; K49-R51 VanDerWaalsContact C-N 3.32Å; K49-R51 PolarHBondContact O-N 3.14Å; K49-R52 PolarHBondContact O-N 3.35Å; K49-H53 PolarHBondContact O-N 3.37Å
50L84.5Confident86.6Confident4 Ų451.4 Ų51.42%0.02125%0.251CS..Hα-helixtrans-58.2-41175.1-78.7169000112.2L5 E46 M47 R52 H53 A54 L478 F520L5-L50 HydrophobicContact CD1-CD1 4.42Å; L5-L50 HydrophobicContact CD1-CD2 3.95Å; L5-L50 HydrophobicContact CD1-CG 3.67Å; L5-L50 HydrophobicContact CD2-CD2 3.5Å; L5-L50 VanDerWaalsContact CD2-CD2 3.5Å; L5-L50 HydrophobicContact CD2-CG 4.13Å; L5-L50 HydrophobicContact CG-CD2 4.37Å; E46-L50 HydrophobicContact CG-CD1 4.15Å; E46-L50 PolarHBondContact O-N 3.44Å; M47-L50 HydrophobicContact CE-CD1 4.19Å; M47-L50 PolarHBondContact O-N 3.22Å; M47-L50 HydrophobicContact SD-CB 4.34Å; L50-R52 PolarHBondContact O-N 3.09Å; L50-H53 PolarHBondContact O-N 2.98Å; L50-A54 WeakPolarHBondContact O-CB 3.43Å; L50-A54 PolarHBondContact O-N 2.63Å; L50-L478 HydrophobicContact CB-CD2 4.23Å; L50-F520 HydrophobicContact CD2-CE2 4.11Å; L50-F520 HydrophobicContact CD2-CZ 3.84Å
51R87.1Confident86Confident131 Ų13145.4 Ų45.449%0.49423%0.229SC..Hα-helixtrans-59.6-41.5177.4-77.3175-173.21686.5112.9M47 K49 A54 L55 F475 L478M47-R51 HydrophobicContact CG-CG 4.47Å; M47-R51 WeakPolarHBondContact O-CB 3.42Å; M47-R51 VanDerWaalsContact O-CG 3.25Å; M47-R51 WeakPolarHBondContact O-CG 3.21Å; M47-R51 PolarHBondContact O-N 3.21Å; M47-R51 HydrophobicContact SD-CG 4.5Å; K49-R51 VanDerWaalsContact C-N 3.32Å; K49-R51 PolarHBondContact O-N 3.14Å; R51-A54 PolarHBondContact O-N 3.2Å; R51-L55 WeakPolarHBondContact O-CB 3.33Å; R51-L55 PolarHBondContact O-N 3.28Å; R51-F475 HydrophobicContact CB-CE1 3.85Å; R51-F475 HydrophobicContact CB-CZ 4.35Å; R51-F475 HydrophobicContact CG-CD1 4.14Å; R51-F475 HydrophobicContact CG-CE1 3.63Å; R51-L478 HydrophobicContact CG-CD1 4.06Å
52R85.8Confident85.6Confident141 Ų14141.4 Ų41.453%0.53221%0.208SC..Hα-helixtrans-65-45.1176.8-68-175.4-178.6-176.40.4111.2M1 K49 L50 L55 C56M1-R52 HydrophobicContact CE-CB 4Å; M1-R52 HydrophobicContact SD-CB 4.06Å; K49-R52 PolarHBondContact O-N 3.35Å; L50-R52 PolarHBondContact O-N 3.09Å; R52-L55 WeakPolarHBondContact O-CB 3.45Å; R52-L55 PolarHBondContact O-N 3.37Å; R52-C56 PolarHBondContact O-N 3.5Å; R52-C56 PolarHBondContact O-SG 3.29Å
53H81.6Confident85.4Confident14 Ų1442.7 Ų42.77%0.06522%0.216CC..Hα-helixtrans-65.5-42.2177.9178.759.5000112M1 W2 K49 L50 L55 C56 Q57 F520M1-H53 VanDerWaalsContact SD-CA 3.59Å; M1-H53 HydrophobicContact SD-CB 3.61Å; W2-H53 AromaticContact CE2-CE1 3.52Å; W2-H53 AromaticContact CE2-NE2 3.73Å; W2-H53 AromaticContact CH2-CD2 3.99Å; W2-H53 AromaticContact CH2-NE2 3.68Å; W2-H53 AromaticContact CZ2-CD2 3.7Å; W2-H53 AromaticContact CZ2-CE1 3.31Å; W2-H53 WeakPolarHBondContact CZ2-CE1 3.19Å; W2-H53 AromaticContact CZ2-NE2 3.04Å; W2-H53 WeakPolarHBondContact CZ2-NE2 3.47Å; W2-H53 AromaticContact NE1-CE1 3.57Å; W2-H53 AromaticContact NE1-ND1 4Å; K49-H53 PolarHBondContact O-N 3.37Å; L50-H53 PolarHBondContact O-N 2.98Å; H53-L55 VanDerWaalsContact C-N 3.32Å; H53-L55 PolarHBondContact O-N 2.98Å; H53-C56 PolarHBondContact O-N 2.89Å; H53-Q57 VanDerWaalsContact NE2-CD 3.31Å; H53-Q57 PolarHBondContact NE2-NE2 2.98Å; H53-Q57 PolarHBondContact O-N 3.43Å; H53-F520 AromaticContact CD2-CE1 3.2Å; H53-F520 WeakPolarHBondContact CD2-CE1 3.28Å; H53-F520 AromaticContact CD2-CZ 3.54Å; H53-F520 AromaticContact NE2-CD1 4Å; H53-F520 AromaticContact NE2-CE1 3.17Å; H53-F520 WeakPolarHBondContact NE2-CE1 3.42Å; H53-F520 AromaticContact NE2-CZ 3.88Å
54A81.8Confident85Confident1 Ų142.9 Ų42.91%0.00822%0.217CC..Hα-helixtrans-58.6-39.7172.800000113.2L50 R51 Q57 A58 R474 L478L50-A54 WeakPolarHBondContact O-CB 3.43Å; L50-A54 PolarHBondContact O-N 2.63Å; R51-A54 PolarHBondContact O-N 3.2Å; A54-Q57 PolarHBondContact O-N 2.86Å; A54-A58 WeakPolarHBondContact O-CB 3.42Å; A54-A58 PolarHBondContact O-N 2.92Å; A54-R474 HydrophobicContact CB-CG 3.41Å; A54-R474 VanDerWaalsContact CB-CG 3.41Å; A54-L478 HydrophobicContact CB-CD1 3.59Å
55L87.4Confident84.2Confident76 Ų7642 Ų4240%0.39820%0.204SC..Hα-helixtrans-61.8-48.5175.5179.463.9000110.8R51 R52 H53 Q57 A58 V59 I471R51-L55 WeakPolarHBondContact O-CB 3.33Å; R51-L55 PolarHBondContact O-N 3.28Å; R52-L55 WeakPolarHBondContact O-CB 3.45Å; R52-L55 PolarHBondContact O-N 3.37Å; H53-L55 VanDerWaalsContact C-N 3.32Å; H53-L55 PolarHBondContact O-N 2.98Å; L55-Q57 VanDerWaalsContact C-N 3.34Å; L55-Q57 PolarHBondContact O-N 3.12Å; L55-A58 PolarHBondContact O-N 2.88Å; L55-V59 WeakPolarHBondContact O-CG2 3.46Å; L55-V59 PolarHBondContact O-N 2.9Å; L55-I471 HydrophobicContact CD1-CD1 3.89Å; L55-I471 HydrophobicContact CD1-CG1 4.02Å
56C83.6Confident83.8Confident71 Ų7138.3 Ų38.348%0.4819%0.187SC..Hα-helixtrans-57.6-46.9176.9-64.80000111.7R52 H53 V59 V60R52-C56 PolarHBondContact O-N 3.5Å; R52-C56 PolarHBondContact O-SG 3.29Å; H53-C56 PolarHBondContact O-N 2.89Å; C56-V59 PolarHBondContact O-N 2.85Å; C56-V60 WeakPolarHBondContact O-CG2 3.48Å; C56-V60 PolarHBondContact O-N 2.96Å; C56-V60 VanDerWaalsContact O-N 3.16Å
57Q79.8Confident83.7Confident14 Ų1440.4 Ų40.47%0.06520%0.2CC..Hα-helixtrans-67.1-36.9178-74.6-169-24.300113.2H53 A54 L55 V59 V60 I61 F520H53-Q57 VanDerWaalsContact NE2-CD 3.31Å; H53-Q57 PolarHBondContact NE2-NE2 2.98Å; H53-Q57 PolarHBondContact O-N 3.43Å; A54-Q57 PolarHBondContact O-N 2.86Å; L55-Q57 VanDerWaalsContact C-N 3.34Å; L55-Q57 PolarHBondContact O-N 3.12Å; Q57-V59 VanDerWaalsContact C-N 3.31Å; Q57-V59 PolarHBondContact O-N 3.25Å; Q57-V60 PolarHBondContact O-N 2.96Å; Q57-I61 WeakPolarHBondContact O-CB 3.48Å; Q57-I61 VanDerWaalsContact O-CG1 3.28Å; Q57-I61 WeakPolarHBondContact O-CG1 3.41Å; Q57-I61 PolarHBondContact O-N 2.84Å; Q57-F520 VanDerWaalsContact OE1-CE1 3.23Å
58A84.2Confident83.6Confident0 Ų040.9 Ų40.90%021%0.206CC..Hα-helixtrans-61.9-40.3176.300000111.5A54 L55 G62 A470 I471 R474A54-A58 WeakPolarHBondContact O-CB 3.42Å; A54-A58 PolarHBondContact O-N 2.92Å; L55-A58 PolarHBondContact O-N 2.88Å; A58-G62 PolarHBondContact O-N 3.42Å; A58-A470 HydrophobicContact CB-CB 4.17Å; A58-A470 WeakPolarHBondContact O-CB 3.48Å; A58-I471 HydrophobicContact CB-CB 4.46Å; A58-I471 HydrophobicContact CB-CG1 3.79Å; A58-R474 HydrophobicContact CB-CB 4.28Å
59V86.7Confident83.4Confident64 Ų6436.5 Ų36.539%0.38819%0.185SC..Hα-helixtrans-63.5-47.8175174.10000111.1L55 C56 Q57 I61 G62 S63 V467L55-V59 WeakPolarHBondContact O-CG2 3.46Å; L55-V59 PolarHBondContact O-N 2.9Å; C56-V59 PolarHBondContact O-N 2.85Å; Q57-V59 VanDerWaalsContact C-N 3.31Å; Q57-V59 PolarHBondContact O-N 3.25Å; V59-I61 PolarHBondContact O-N 3.25Å; V59-G62 PolarHBondContact O-N 3.06Å; V59-S63 WeakPolarHBondContact O-CB 3.42Å; V59-S63 PolarHBondContact O-N 3.45Å; V59-S63 PolarHBondContact O-OG 2.92Å; V59-V467 HydrophobicContact CG2-CG1 4.2Å
60V83.1Confident83.5Confident51 Ų5138.1 Ų38.131%0.30920%0.195SC..Hα-helixtrans-60.8-43.8178.3173.30000112C56 Q57 S63 Y64 P110C56-V60 WeakPolarHBondContact O-CG2 3.48Å; C56-V60 PolarHBondContact O-N 2.96Å; C56-V60 VanDerWaalsContact O-N 3.16Å; Q57-V60 PolarHBondContact O-N 2.96Å; V60-S63 PolarHBondContact O-OG 3.32Å; V60-S63 VanDerWaalsContact O-OG 3.05Å; V60-Y64 PolarHBondContact O-N 2.78Å; V60-P110 HydrophobicContact CG1-CB 4.43Å
61I80.4Confident83.6Confident7 Ų739.7 Ų39.74%0.03621%0.208CC..Hα-helixtrans-70.7-37.8178.9-67169.6000111Q57 V59 Y64 N523Q57-I61 WeakPolarHBondContact O-CB 3.48Å; Q57-I61 VanDerWaalsContact O-CG1 3.28Å; Q57-I61 WeakPolarHBondContact O-CG1 3.41Å; Q57-I61 PolarHBondContact O-N 2.84Å; V59-I61 PolarHBondContact O-N 3.25Å; I61-Y64 WeakPolarHBondContact O-CB 3.37Å; I61-N523 HydrophobicContact CD1-CB 4.07Å
62G82.8Confident83.6Confident1 Ų133.8 Ų33.81%0.0119%0.187CC..Hα-helixtrans-65.7-43.1176.900000112.4A58 V59 Y64 S466A58-G62 PolarHBondContact O-N 3.42Å; V59-G62 PolarHBondContact O-N 3.06Å; G62-Y64 VanDerWaalsContact C-N 3.34Å; G62-Y64 PolarHBondContact O-N 3.47Å; G62-S466 WeakPolarHBondContact O-CB 3.46Å; G62-S466 PolarHBondContact O-OG 2.93Å
63S84.4Confident83.6Confident37 Ų3728.5 Ų28.526%0.25917%0.169SC..Hα-helixtrans-70.8-28.2-179.865.80000113.2V59 V60 Y65 V66 T67V59-S63 WeakPolarHBondContact O-CB 3.42Å; V59-S63 PolarHBondContact O-N 3.45Å; V59-S63 PolarHBondContact O-OG 2.92Å; V60-S63 PolarHBondContact O-OG 3.32Å; V60-S63 VanDerWaalsContact O-OG 3.05Å; S63-Y65 PolarHBondContact O-N 3.32Å; S63-V66 PolarHBondContact O-N 3Å; S63-T67 PolarHBondContact O-N 3.05Å; S63-T67 PolarHBondContact O-OG1 3.02Å
64Y82.3Confident83.9Confident4 Ų429.9 Ų29.92%0.01619%0.187CC..Hα-helixtrans-50.8-33.5179.8174.2-97.2000114.6V60 I61 G62 V66 R102 L107 R527V60-Y64 PolarHBondContact O-N 2.78Å; I61-Y64 WeakPolarHBondContact O-CB 3.37Å; G62-Y64 VanDerWaalsContact C-N 3.34Å; G62-Y64 PolarHBondContact O-N 3.47Å; Y64-V66 PolarHBondContact O-N 2.68Å; Y64-R102 HydrophobicContact CD2-CG 4.45Å; Y64-R102 HydrophobicContact CE2-CG 4.11Å; Y64-R102 WeakPolarHBondContact O-CD 3.34Å; Y64-R102 PolarHBondContact O-NH1 3.46Å; Y64-R102 PolarHBondContact OH-NH1 3.42Å; Y64-R102 PolarHBondContact OH-NH2 3.35Å; Y64-L107 HydrophobicContact CD2-CB 4.3Å; Y64-L107 HydrophobicContact CE2-CB 4.05Å; Y64-R527 VanDerWaalsContact CD1-CZ 3.43Å; Y64-R527 PolarHBondContact OH-NH2 3.42Å
65Y73.9Confident84.1Confident26 Ų2631.7 Ų31.710%0.10220%0.202CC..Hα-helixtrans-71.6-19.8179.5-76.5-82.2000113.6S63 R69 Y406S63-Y65 PolarHBondContact O-N 3.32Å; Y65-R69 PolarHBondContact O-NH1 3.07Å; Y65-R69 VanDerWaalsContact O-NH1 3.15Å; Y65-Y406 AromaticContact CD1-CD2 3.88Å; Y65-Y406 HydrophobicContact CD1-CD2 3.88Å; Y65-Y406 AromaticContact CD1-CE2 3.97Å; Y65-Y406 HydrophobicContact CD1-CE2 3.97Å; Y65-Y406 WeakPolarHBondContact O-CE2 3.28Å
66V83.4Confident83.9Confident0 Ų028.7 Ų28.70%019%0.186CC..Hα-helixtrans-113.2-22.7-171.1-164.30000111.6S63 Y64 G68 R69 I70 I459 L462 L463S63-V66 PolarHBondContact O-N 3Å; Y64-V66 PolarHBondContact O-N 2.68Å; V66-G68 VanDerWaalsContact C-N 3.3Å; V66-G68 PolarHBondContact O-N 3.22Å; V66-G68 VanDerWaalsContact O-N 3.16Å; V66-R69 WeakPolarHBondContact O-CA 3.49Å; V66-R69 PolarHBondContact O-N 2.91Å; V66-I70 HydrophobicContact CB-CD1 4.18Å; V66-I70 HydrophobicContact CG1-CD1 3.67Å; V66-I70 HydrophobicContact CG1-CG1 3.87Å; V66-I70 PolarHBondContact O-N 2.71Å; V66-I459 HydrophobicContact CG1-CB 4.46Å; V66-I459 HydrophobicContact CG1-CG2 3.35Å; V66-L462 HydrophobicContact CG2-CB 4.34Å; V66-L462 HydrophobicContact CG2-CD2 4.12Å; V66-L462 HydrophobicContact CG2-CG 3.91Å; V66-L463 HydrophobicContact CB-CB 4.31Å; V66-L463 HydrophobicContact CB-CD1 4.15Å; V66-L463 HydrophobicContact CG1-CB 4.17Å; V66-L463 HydrophobicContact CG2-CB 3.96Å; V66-L463 HydrophobicContact CG2-CD1 4.15Å
67T85.6Confident83.8Confident48 Ų4827 Ų2729%0.29418%0.178SC..Hα-helixtrans-52.2-43.7-177.2-46.30000113.8S63 R69 I70 A71 S106S63-T67 PolarHBondContact O-N 3.05Å; S63-T67 PolarHBondContact O-OG1 3.02Å; T67-R69 VanDerWaalsContact C-N 3.31Å; T67-R69 PolarHBondContact O-N 2.96Å; T67-I70 PolarHBondContact O-N 3.13Å; T67-A71 WeakPolarHBondContact O-CB 3.39Å; T67-A71 PolarHBondContact O-N 3.49Å; T67-S106 WeakPolarHBondContact CB-OG 3.14Å; T67-S106 WeakPolarHBondContact CG2-OG 3.49Å
68G83.4Confident84.1Confident13 Ų1329 Ų2913%0.13420%0.196CC..Hα-helixtrans-65-34.6178.600000113.2V66 L72V66-G68 VanDerWaalsContact C-N 3.3Å; V66-G68 PolarHBondContact O-N 3.22Å; V66-G68 VanDerWaalsContact O-N 3.16Å; G68-L72 WeakPolarHBondContact O-CB 3.4Å; G68-L72 PolarHBondContact O-N 3.04Å
69R83.6Confident83.9Confident13 Ų1332.2 Ų32.25%0.04921%0.209CC..Hα-helixtrans-77.3-36.6177.8-64.1-162.2-175.686.4-2.2112.5Y65 V66 T67 A71 L72 L73 Y406 D410 W455 I459 L462Y65-R69 PolarHBondContact O-NH1 3.07Å; Y65-R69 VanDerWaalsContact O-NH1 3.15Å; V66-R69 WeakPolarHBondContact O-CA 3.49Å; V66-R69 PolarHBondContact O-N 2.91Å; T67-R69 VanDerWaalsContact C-N 3.31Å; T67-R69 PolarHBondContact O-N 2.96Å; R69-A71 VanDerWaalsContact C-N 3.3Å; R69-L72 PolarHBondContact O-N 3.36Å; R69-L73 VanDerWaalsContact O-CB 3.24Å; R69-L73 WeakPolarHBondContact O-CB 3.11Å; R69-L73 PolarHBondContact O-N 2.91Å; R69-Y406 VanDerWaalsContact CZ-CE2 3.45Å; R69-Y406 VanDerWaalsContact NH2-CD2 3.27Å; R69-Y406 VanDerWaalsContact NH2-CG 3.26Å; R69-Y406 PolarHBondContact NH2-O 2.81Å; R69-D410 IonicContact CZ-OD1 3.97Å; R69-D410 IonicContact NE-OD1 3.17Å; R69-D410 PolarHBondContact NE-OD1 3.32Å; R69-D410 VanDerWaalsContact NE-OD1 3.13Å; R69-D410 IonicContact NH2-OD1 3.34Å; R69-D410 PolarHBondContact NH2-OD1 3.4Å; R69-D410 IonicContact NH2-OD2 3.07Å; R69-D410 PolarHBondContact NH2-OD2 3.49Å; R69-W455 HydrophobicContact CB-CZ2 4.47Å; R69-I459 HydrophobicContact CB-CD1 3.85Å; R69-I459 HydrophobicContact CB-CG1 4.02Å; R69-I459 HydrophobicContact CB-CG2 4.43Å; R69-L462 VanDerWaalsContact NH1-CD2 3.32Å
70I87.3Confident83.5Confident84 Ų8432.1 Ų32.143%0.43121%0.208SC..Hα-helixtrans-62.2-42.6172.9-69.7160000110V66 T67 L73 G74 I459V66-I70 HydrophobicContact CB-CD1 4.18Å; V66-I70 HydrophobicContact CG1-CD1 3.67Å; V66-I70 HydrophobicContact CG1-CG1 3.87Å; V66-I70 PolarHBondContact O-N 2.71Å; T67-I70 PolarHBondContact O-N 3.13Å; I70-L73 PolarHBondContact O-N 3.39Å; I70-G74 PolarHBondContact O-N 3.04Å; I70-I459 HydrophobicContact CG1-CG2 3.84Å
71A87.9Confident83.4Confident37 Ų3736.7 Ų36.731%0.30623%0.23SC..Hα-helixtrans-63.6-45.2175.700000111.9T67 R69 G74 A75 F98T67-A71 WeakPolarHBondContact O-CB 3.39Å; T67-A71 PolarHBondContact O-N 3.49Å; R69-A71 VanDerWaalsContact C-N 3.3Å; A71-G74 PolarHBondContact O-N 3.45Å; A71-A75 PolarHBondContact O-N 3.32Å; A71-F98 HydrophobicContact CB-CD1 3.63Å; A71-F98 HydrophobicContact CB-CE1 3.93Å; A71-F98 HydrophobicContact CB-CG 4Å
72L86.8Confident83.6Confident8 Ų840.4 Ų40.44%0.04225%0.253CS..Hα-helixtrans-62.2-43.2175.5-178.162.4000112G68 R69 G74 A75 L76 A95 F98 L413 W455G68-L72 WeakPolarHBondContact O-CB 3.4Å; G68-L72 PolarHBondContact O-N 3.04Å; R69-L72 PolarHBondContact O-N 3.36Å; L72-G74 PolarHBondContact O-N 3.3Å; L72-A75 PolarHBondContact O-N 2.89Å; L72-L76 HydrophobicContact CD1-CD1 4.14Å; L72-L76 HydrophobicContact CD1-CG 4.11Å; L72-L76 HydrophobicContact CG-CD1 3.95Å; L72-L76 HydrophobicContact CG-CG 4.32Å; L72-L76 WeakPolarHBondContact O-CB 3.33Å; L72-L76 WeakPolarHBondContact O-CG 3.45Å; L72-L76 PolarHBondContact O-N 2.74Å; L72-A95 HydrophobicContact CD2-CB 3.85Å; L72-F98 HydrophobicContact CB-CD2 4.17Å; L72-F98 HydrophobicContact CD1-CD2 4.15Å; L72-F98 HydrophobicContact CD1-CE2 4.46Å; L72-L413 HydrophobicContact CD2-CD2 4.07Å; L72-W455 HydrophobicContact CB-CH2 4.22Å; L72-W455 HydrophobicContact CD2-CH2 3.85Å; L72-W455 HydrophobicContact CD2-CZ2 4.22Å; L72-W455 HydrophobicContact CG-CH2 3.97Å
73L86.7Confident83.2Confident29 Ų2947.9 Ų47.915%0.15229%0.293CS..Hα-helixtrans-59.4-46.1175.8178.869.7000111.5R69 I70 A75 L76 A77 L452 W455 T456 I459R69-L73 VanDerWaalsContact O-CB 3.24Å; R69-L73 WeakPolarHBondContact O-CB 3.11Å; R69-L73 PolarHBondContact O-N 2.91Å; I70-L73 PolarHBondContact O-N 3.39Å; L73-A75 VanDerWaalsContact C-N 3.34Å; L73-A75 PolarHBondContact O-N 3.47Å; L73-L76 PolarHBondContact O-N 3.15Å; L73-A77 WeakPolarHBondContact O-CB 3.27Å; L73-A77 PolarHBondContact O-N 3.16Å; L73-L452 HydrophobicContact CD1-CD1 3.6Å; L73-L452 HydrophobicContact CD1-CG 4.18Å; L73-W455 HydrophobicContact CB-CE3 4.44Å; L73-W455 HydrophobicContact CB-CH2 4.3Å; L73-W455 HydrophobicContact CB-CZ3 3.68Å; L73-W455 HydrophobicContact CD1-CE3 3.63Å; L73-W455 HydrophobicContact CD1-CZ3 3.61Å; L73-W455 HydrophobicContact CG-CZ3 4.26Å; L73-T456 WeakPolarHBondContact CD1-OG1 3.2Å; L73-T456 HydrophobicContact CD2-CG2 3.89Å; L73-I459 HydrophobicContact CB-CD1 4.27Å; L73-I459 HydrophobicContact CD2-CD1 4.32Å
74G87.2Confident82.6Confident43 Ų4352.3 Ų52.344%0.44331%0.308SS..Hα-helixtrans-60.9-42.1175.600000112.5I70 A71 L72 A78I70-G74 PolarHBondContact O-N 3.04Å; A71-G74 PolarHBondContact O-N 3.45Å; L72-G74 PolarHBondContact O-N 3.3Å; G74-A78 WeakPolarHBondContact O-CB 3.3Å; G74-A78 PolarHBondContact O-N 3.37Å
75A86.4Confident81.8Confident39 Ų3956 Ų5632%0.32234%0.339SS..Hα-helixtrans-66.5-44.6177.700000112.5A71 L72 L73 A78 Y79 F98A71-A75 PolarHBondContact O-N 3.32Å; L72-A75 PolarHBondContact O-N 2.89Å; L73-A75 VanDerWaalsContact C-N 3.34Å; L73-A75 PolarHBondContact O-N 3.47Å; A75-A78 PolarHBondContact O-N 3.48Å; A75-Y79 WeakPolarHBondContact O-CB 3.07Å; A75-Y79 PolarHBondContact O-N 3.39Å; A75-F98 HydrophobicContact CB-CE2 3.59Å; A75-F98 HydrophobicContact CB-CZ 3.8Å
76L82.7Confident81.6Confident14 Ų1456.7 Ų56.77%0.07335%0.346CS..Hα-helixtrans-66.9-41.8177.4-68.4176.2000111.5L72 L73 A78 Y79 V80 V86 V91 W455L72-L76 HydrophobicContact CD1-CD1 4.14Å; L72-L76 HydrophobicContact CD1-CG 4.11Å; L72-L76 HydrophobicContact CG-CD1 3.95Å; L72-L76 HydrophobicContact CG-CG 4.32Å; L72-L76 WeakPolarHBondContact O-CB 3.33Å; L72-L76 WeakPolarHBondContact O-CG 3.45Å; L72-L76 PolarHBondContact O-N 2.74Å; L73-L76 PolarHBondContact O-N 3.15Å; L76-A78 PolarHBondContact O-N 3.3Å; L76-Y79 PolarHBondContact O-N 3.35Å; L76-V80 VanDerWaalsContact O-CG2 3.28Å; L76-V80 WeakPolarHBondContact O-CG2 3.33Å; L76-V80 PolarHBondContact O-N 3.15Å; L76-V86 HydrophobicContact CD2-CG1 3.97Å; L76-V91 HydrophobicContact CD2-CG2 3.88Å; L76-W455 HydrophobicContact CD1-CZ3 4.27Å
77A81.8Confident80.9Confident36 Ų3659.7 Ų59.730%0.29836%0.364SS..Hα-helixtrans-60.3-45.4174.900000111.3L73 Y79 V80 L81L73-A77 WeakPolarHBondContact O-CB 3.27Å; L73-A77 PolarHBondContact O-N 3.16Å; A77-Y79 VanDerWaalsContact C-N 3.33Å; A77-Y79 PolarHBondContact O-N 3.5Å; A77-V80 PolarHBondContact O-N 2.73Å; A77-L81 VanDerWaalsContact O-CG 3.32Å; A77-L81 WeakPolarHBondContact O-CG 3.45Å; A77-L81 PolarHBondContact O-N 3.19Å; A77-L81 VanDerWaalsContact O-N 3.09Å
78A84.7Confident80Confident55 Ų5559 Ų5946%0.45536%0.361SS..Hα-helixtrans-62.6-39.4174.900000112.2G74 A75 L76 L81 T82G74-A78 WeakPolarHBondContact O-CB 3.3Å; G74-A78 PolarHBondContact O-N 3.37Å; A75-A78 PolarHBondContact O-N 3.48Å; L76-A78 PolarHBondContact O-N 3.3Å; A78-L81 PolarHBondContact O-N 3.08Å; A78-T82 PolarHBondContact O-N 2.83Å
79Y81.4Confident79.3Confident67 Ų6765.2 Ų65.226%0.26339%0.387SS..Hα-helixtrans-66.1-42.8178.4-162.4-93000112A75 L76 A77 L81 T82 K84 A85 V86 V90A75-Y79 WeakPolarHBondContact O-CB 3.07Å; A75-Y79 PolarHBondContact O-N 3.39Å; L76-Y79 PolarHBondContact O-N 3.35Å; A77-Y79 VanDerWaalsContact C-N 3.33Å; A77-Y79 PolarHBondContact O-N 3.5Å; Y79-L81 VanDerWaalsContact C-N 3.32Å; Y79-L81 PolarHBondContact O-N 2.81Å; Y79-T82 PolarHBondContact O-N 3.29Å; Y79-T82 VanDerWaalsContact O-N 3.1Å; Y79-T82 PolarHBondContact O-OG1 2.89Å; Y79-K84 HydrophobicContact CD1-CB 4.1Å; Y79-K84 HydrophobicContact CE1-CB 3.48Å; Y79-K84 VanDerWaalsContact CE1-CB 3.48Å; Y79-K84 HydrophobicContact CE2-CB 4.44Å; Y79-K84 HydrophobicContact CE2-CD 4.18Å; Y79-A85 WeakPolarHBondContact CE1-O 3.45Å; Y79-V86 HydrophobicContact CD1-CG2 3.87Å; Y79-V86 HydrophobicContact CE1-CG2 4.46Å; Y79-V90 HydrophobicContact CE2-CG1 4.49Å
80V77.1Confident79Confident63 Ų6367.2 Ų67.238%0.38240%0.4SS..Hα-helixtrans-62-38.3175.6171.60000111.5L76 A77 T82 N83 V86L76-V80 VanDerWaalsContact O-CG2 3.28Å; L76-V80 WeakPolarHBondContact O-CG2 3.33Å; L76-V80 PolarHBondContact O-N 3.15Å; A77-V80 PolarHBondContact O-N 2.73Å; V80-T82 PolarHBondContact O-N 3.47Å; V80-T82 VanDerWaalsContact O-N 3.17Å; V80-N83 PolarHBondContact O-N 3.15Å; V80-V86 HydrophobicContact CG2-CG2 3.67Å
81L82.1Confident78.4Confident147 Ų14763.7 Ų63.777%0.7738%0.383SS*.Hα-helixtrans-63-19.6176-71.4170.6000113.7A77 A78 Y79 N83A77-L81 VanDerWaalsContact O-CG 3.32Å; A77-L81 WeakPolarHBondContact O-CG 3.45Å; A77-L81 PolarHBondContact O-N 3.19Å; A77-L81 VanDerWaalsContact O-N 3.09Å; A78-L81 PolarHBondContact O-N 3.08Å; Y79-L81 VanDerWaalsContact C-N 3.32Å; Y79-L81 PolarHBondContact O-N 2.81Å; L81-N83 VanDerWaalsContact C-N 3.29Å
82T84.5Confident77.7Confident85 Ų8564.2 Ų64.252%0.52138%0.378SS..THydrogen-bonded Turntrans-86.77.3175.366.60000114.1A78 Y79 V80 K84A78-T82 PolarHBondContact O-N 2.83Å; Y79-T82 PolarHBondContact O-N 3.29Å; Y79-T82 VanDerWaalsContact O-N 3.1Å; Y79-T82 PolarHBondContact O-OG1 2.89Å; V80-T82 PolarHBondContact O-N 3.47Å; V80-T82 VanDerWaalsContact O-N 3.17Å; T82-K84 PolarHBondContact O-N 3.43Å; T82-K84 VanDerWaalsContact O-N 3.16Å
83N73.9Confident77.3Confident158 Ų15867.4 Ų67.485%0.84540%0.398SS*.THydrogen-bonded Turntrans55.525-176.1-74.3-24.2000114.4V80 L81V80-N83 PolarHBondContact O-N 3.15Å; L81-N83 VanDerWaalsContact C-N 3.29Å
84K71.1Confident77Confident130 Ų13066.7 Ų66.757%0.56540%0.397SS*.  trans-90.2139.6173.1-71.5-177.3178.7-179.10110.6Y79 T82 V86Y79-K84 HydrophobicContact CD1-CB 4.1Å; Y79-K84 HydrophobicContact CE1-CB 3.48Å; Y79-K84 VanDerWaalsContact CE1-CB 3.48Å; Y79-K84 HydrophobicContact CE2-CB 4.44Å; Y79-K84 HydrophobicContact CE2-CD 4.18Å; T82-K84 PolarHBondContact O-N 3.43Å; T82-K84 VanDerWaalsContact O-N 3.16Å; K84-V86 PolarHBondContact O-N 2.98Å
85A67Low76.5Confident81 Ų8165.6 Ų65.667%0.66938%0.384SS*.  trans-64.1120.7173.800000110Y79 T87Y79-A85 WeakPolarHBondContact CE1-O 3.45Å; A85-T87 PolarHBondContact O-N 3.44Å; A85-T87 VanDerWaalsContact O-N 3.08Å
86V68.1Low76.1Confident41 Ų4166 Ų6625%0.24839%0.388CS..  trans-67.5104.9173.9177.80000107.9L76 Y79 V80 K84 V91L76-V86 HydrophobicContact CD2-CG1 3.97Å; Y79-V86 HydrophobicContact CD1-CG2 3.87Å; Y79-V86 HydrophobicContact CE1-CG2 4.46Å; V80-V86 HydrophobicContact CG2-CG2 3.67Å; K84-V86 PolarHBondContact O-N 2.98Å; V86-V91 HydrophobicContact CG1-CG2 3.42Å; V86-V91 VanDerWaalsContact CG1-CG2 3.42Å
87T69.7Low76.2Confident63 Ų6371.6 Ų71.639%0.38742%0.415SS..  trans-85.8153.1174.963.40000110.4A85 E89 V90 V91A85-T87 PolarHBondContact O-N 3.44Å; A85-T87 VanDerWaalsContact O-N 3.08Å; T87-E89 PolarHBondContact O-N 3.5Å; T87-V90 PolarHBondContact O-N 2.92Å; T87-V90 VanDerWaalsContact O-N 3.15Å; T87-V90 WeakPolarHBondContact OG1-CG2 3.49Å; T87-V91 PolarHBondContact O-N 3.33Å
88S65.6Low76.4Confident32 Ų3273.2 Ų73.222%0.22442%0.415CS..Hα-helixtrans-52.3-40.2174.249.20000114.4V90 V91 F92 E417 K421S88-V90 VanDerWaalsContact C-N 3.31Å; S88-V90 PolarHBondContact O-N 3.29Å; S88-V91 PolarHBondContact O-N 3.16Å; S88-F92 WeakPolarHBondContact O-CD2 3.31Å; S88-F92 PolarHBondContact O-N 3.31Å; S88-E417 VanDerWaalsContact CA-CD 3.5Å; S88-E417 VanDerWaalsContact CA-OE2 3.3Å; S88-E417 WeakPolarHBondContact CA-OE2 3.5Å; S88-E417 WeakPolarHBondContact CB-OE1 3.41Å; S88-E417 WeakPolarHBondContact CB-OE2 3.21Å; S88-K421 WeakPolarHBondContact OG-CE 3.47Å; S88-K421 PolarHBondContact OG-NZ 3.04Å; S88-K421 VanDerWaalsContact OG-NZ 3.09Å
89E70.1Confident76Confident145 Ų14572 Ų7268%0.67840%0.402SS*.Hα-helixtrans-61.5-44.3-178.9-173.4-179.9176.300110.1T87 V91 V93T87-E89 PolarHBondContact O-N 3.5Å; E89-V91 PolarHBondContact O-N 3.25Å; E89-V93 HydrophobicContact CG-CG2 4.18Å; E89-V93 WeakPolarHBondContact O-CB 3.43Å; E89-V93 WeakPolarHBondContact O-CG2 3.49Å; E89-V93 PolarHBondContact O-N 3.5Å
90V76.4Confident75.8Confident54 Ų5472 Ų7233%0.32742%0.415SS..Hα-helixtrans-65.2-41.2178.8174.70000111.5Y79 T87 S88 G94Y79-V90 HydrophobicContact CE2-CG1 4.49Å; T87-V90 PolarHBondContact O-N 2.92Å; T87-V90 VanDerWaalsContact O-N 3.15Å; T87-V90 WeakPolarHBondContact OG1-CG2 3.49Å; S88-V90 VanDerWaalsContact C-N 3.31Å; S88-V90 PolarHBondContact O-N 3.29Å; V90-G94 WeakPolarHBondContact O-CA 3.27Å; V90-G94 PolarHBondContact O-N 3.19Å
91V75.8Confident76.2Confident11 Ų1170.9 Ų70.97%0.06741%0.412CS..Hα-helixtrans-64.6-51.4179.8178.10000110.9L76 V86 T87 S88 E89 G94 A95 L413L76-V91 HydrophobicContact CD2-CG2 3.88Å; V86-V91 HydrophobicContact CG1-CG2 3.42Å; V86-V91 VanDerWaalsContact CG1-CG2 3.42Å; T87-V91 PolarHBondContact O-N 3.33Å; S88-V91 PolarHBondContact O-N 3.16Å; E89-V91 PolarHBondContact O-N 3.25Å; V91-G94 PolarHBondContact O-N 2.97Å; V91-A95 VanDerWaalsContact O-CB 3.24Å; V91-A95 WeakPolarHBondContact O-CB 3.33Å; V91-A95 PolarHBondContact O-N 3.15Å; V91-L413 HydrophobicContact CG1-CD1 3.95Å; V91-L413 HydrophobicContact CG1-CD2 3.77Å; V91-L413 HydrophobicContact CG1-CG 3.95Å
92F71.5Confident76.3Confident47 Ų4764.5 Ų64.521%0.20638%0.378CS..Hα-helixtrans-74-39.6-176.6-79.5-65.2000113.3S88 G94 A95 A96 E417S88-F92 WeakPolarHBondContact O-CD2 3.31Å; S88-F92 PolarHBondContact O-N 3.31Å; F92-G94 VanDerWaalsContact C-N 3.33Å; F92-A95 PolarHBondContact O-N 2.97Å; F92-A96 VanDerWaalsContact O-CB 3.31Å; F92-A96 WeakPolarHBondContact O-CB 3.31Å; F92-A96 PolarHBondContact O-N 3.38Å; F92-E417 VanDerWaalsContact CD2-OE2 3.27Å; F92-E417 WeakPolarHBondContact CD2-OE2 3.4Å; F92-E417 VanDerWaalsContact CE2-CD 3.44Å; F92-E417 WeakPolarHBondContact CE2-OE1 3.47Å; F92-E417 WeakPolarHBondContact CE2-OE2 3.45Å
93V79.1Confident75.9Confident75 Ų7563.4 Ų63.446%0.45537%0.369SS..Hα-helixtrans-63.6-44.3173.3174.20000109.5E89 A96 M97E89-V93 HydrophobicContact CG-CG2 4.18Å; E89-V93 WeakPolarHBondContact O-CB 3.43Å; E89-V93 WeakPolarHBondContact O-CG2 3.49Å; E89-V93 PolarHBondContact O-N 3.5Å; V93-A96 PolarHBondContact O-N 3.43Å; V93-M97 HydrophobicContact CG1-CG 4.31Å; V93-M97 HydrophobicContact CG1-SD 3.92Å; V93-M97 WeakPolarHBondContact O-CB 3.02Å; V93-M97 VanDerWaalsContact O-CG 3.25Å; V93-M97 WeakPolarHBondContact O-CG 3.09Å; V93-M97 PolarHBondContact O-N 2.95Å
94G80.9Confident76.4Confident14 Ų1459.8 Ų59.814%0.14435%0.352CS..Hα-helixtrans-59-48.5174.300000112.4V90 V91 F92 A96 M97 F98V90-G94 WeakPolarHBondContact O-CA 3.27Å; V90-G94 PolarHBondContact O-N 3.19Å; V91-G94 PolarHBondContact O-N 2.97Å; F92-G94 VanDerWaalsContact C-N 3.33Å; G94-A96 VanDerWaalsContact C-N 3.35Å; G94-A96 PolarHBondContact O-N 3.18Å; G94-M97 PolarHBondContact O-N 2.92Å; G94-F98 WeakPolarHBondContact O-CB 3.02Å; G94-F98 WeakPolarHBondContact O-CD2 3.43Å; G94-F98 PolarHBondContact O-N 3.02Å
95A77.4Confident77.2Confident21 Ų2158.7 Ų58.717%0.17435%0.352CS..Hα-helixtrans-60.5-42.9177.600000112L72 V91 F92 N99L72-A95 HydrophobicContact CD2-CB 3.85Å; V91-A95 VanDerWaalsContact O-CB 3.24Å; V91-A95 WeakPolarHBondContact O-CB 3.33Å; V91-A95 PolarHBondContact O-N 3.15Å; F92-A95 PolarHBondContact O-N 2.97Å; A95-N99 WeakPolarHBondContact O-CB 3.28Å; A95-N99 PolarHBondContact O-N 3.45Å
96A77.3Confident77.8Confident48 Ų4855.7 Ų55.740%0.39733%0.326SS..Hα-helixtrans-63.9-46.8176.600000111.7F92 V93 G94 N99 A100F92-A96 VanDerWaalsContact O-CB 3.31Å; F92-A96 WeakPolarHBondContact O-CB 3.31Å; F92-A96 PolarHBondContact O-N 3.38Å; V93-A96 PolarHBondContact O-N 3.43Å; G94-A96 VanDerWaalsContact C-N 3.35Å; G94-A96 PolarHBondContact O-N 3.18Å; A96-N99 PolarHBondContact O-N 3.46Å; A96-A100 WeakPolarHBondContact O-CB 3.31Å; A96-A100 PolarHBondContact O-N 3.1Å
97M84.4Confident78.2Confident130 Ų13054 Ų5464%0.6432%0.316SS*.Hα-helixtrans-63.3-47.8178.2-71.2-178.380.300112V93 G94 N99 A100 A101V93-M97 HydrophobicContact CG1-CG 4.31Å; V93-M97 HydrophobicContact CG1-SD 3.92Å; V93-M97 WeakPolarHBondContact O-CB 3.02Å; V93-M97 VanDerWaalsContact O-CG 3.25Å; V93-M97 WeakPolarHBondContact O-CG 3.09Å; V93-M97 PolarHBondContact O-N 2.95Å; G94-M97 PolarHBondContact O-N 2.92Å; M97-N99 PolarHBondContact O-N 3.46Å; M97-A100 PolarHBondContact O-N 2.94Å; M97-A101 WeakPolarHBondContact O-CB 3.48Å; M97-A101 PolarHBondContact O-N 3.49Å
98F85.8Confident78.9Confident70 Ų7056.6 Ų56.631%0.30732%0.319SS..Hα-helixtrans-66.9-36.1177.7-73.8-57.4000112.2A71 L72 A75 G94 A101 R102A71-F98 HydrophobicContact CB-CD1 3.63Å; A71-F98 HydrophobicContact CB-CE1 3.93Å; A71-F98 HydrophobicContact CB-CG 4Å; L72-F98 HydrophobicContact CB-CD2 4.17Å; L72-F98 HydrophobicContact CD1-CD2 4.15Å; L72-F98 HydrophobicContact CD1-CE2 4.46Å; A75-F98 HydrophobicContact CB-CE2 3.59Å; A75-F98 HydrophobicContact CB-CZ 3.8Å; G94-F98 WeakPolarHBondContact O-CB 3.02Å; G94-F98 WeakPolarHBondContact O-CD2 3.43Å; G94-F98 PolarHBondContact O-N 3.02Å; F98-A101 PolarHBondContact O-N 3.43Å; F98-R102 WeakPolarHBondContact O-CB 3.3Å; F98-R102 PolarHBondContact O-N 3.41Å
99N76.4Confident79.9Confident31 Ų3159.6 Ų59.617%0.16633%0.332CS..Hα-helixtrans-65.6-39.1174.6-174.846.8000112.2A95 A96 M97 R102 F587A95-N99 WeakPolarHBondContact O-CB 3.28Å; A95-N99 PolarHBondContact O-N 3.45Å; A96-N99 PolarHBondContact O-N 3.46Å; M97-N99 PolarHBondContact O-N 3.46Å; N99-R102 PolarHBondContact OD1-NE 3.16Å; N99-R102 VanDerWaalsContact OD1-NE 3.15Å; N99-R102 PolarHBondContact OD1-NH2 2.96Å; N99-F587 HydrophobicContact CB-CE2 3.96Å; N99-F587 HydrophobicContact CB-CZ 4.04Å; N99-F587 VanDerWaalsContact ND2-CE2 3.33Å; N99-F587 WeakPolarHBondContact ND2-CE2 3.32Å; N99-F587 WeakPolarHBondContact ND2-CZ 3.49Å
100A78.3Confident80.5Confident66 Ų6655 Ų5555%0.54532%0.315SS..Hα-helixtrans-64.5-47.4173.500000111.5A96 M97 R102A96-A100 WeakPolarHBondContact O-CB 3.31Å; A96-A100 PolarHBondContact O-N 3.1Å; M97-A100 PolarHBondContact O-N 2.94Å; A100-R102 VanDerWaalsContact C-N 3.34Å; A100-R102 PolarHBondContact O-N 3.31Å
101A85Confident80.6Confident39 Ų3954.4 Ų54.432%0.32231%0.308SS..Hα-helixtrans-65.4-34.217900000113.2M97 F98 L103 T104 L105M97-A101 WeakPolarHBondContact O-CB 3.48Å; M97-A101 PolarHBondContact O-N 3.49Å; F98-A101 PolarHBondContact O-N 3.43Å; A101-L103 VanDerWaalsContact C-N 3.28Å; A101-L103 PolarHBondContact O-N 3.26Å; A101-T104 PolarHBondContact O-N 3.26Å; A101-L105 HydrophobicContact CB-CD1 4.34Å; A101-L105 WeakPolarHBondContact O-CB 3.46Å; A101-L105 WeakPolarHBondContact O-CG 3.38Å; A101-L105 PolarHBondContact O-N 3.42Å
102R83.5Confident81.2Confident14 Ų1456.5 Ų56.55%0.05333%0.327CS..Hα-helixtrans-56.5-39.4-178.9177.1-176.269.5106.5-0.4112.7Y64 F98 N99 A100 S106Y64-R102 HydrophobicContact CD2-CG 4.45Å; Y64-R102 HydrophobicContact CE2-CG 4.11Å; Y64-R102 WeakPolarHBondContact O-CD 3.34Å; Y64-R102 PolarHBondContact O-NH1 3.46Å; Y64-R102 PolarHBondContact OH-NH1 3.42Å; Y64-R102 PolarHBondContact OH-NH2 3.35Å; F98-R102 WeakPolarHBondContact O-CB 3.3Å; F98-R102 PolarHBondContact O-N 3.41Å; N99-R102 PolarHBondContact OD1-NE 3.16Å; N99-R102 VanDerWaalsContact OD1-NE 3.15Å; N99-R102 PolarHBondContact OD1-NH2 2.96Å; A100-R102 VanDerWaalsContact C-N 3.34Å; A100-R102 PolarHBondContact O-N 3.31Å; R102-S106 WeakPolarHBondContact O-CA 3.22Å; R102-S106 WeakPolarHBondContact O-CB 3.48Å; R102-S106 PolarHBondContact O-N 3.15Å; R102-S106 PolarHBondContact O-OG 3.21Å
103L76.2Confident82Confident62 Ų6258 Ų5833%0.32534%0.339SS..Hα-helixtrans-66.3-42.8-178.8-176.2141.8000111.1A101 L107 Y108A101-L103 VanDerWaalsContact C-N 3.28Å; A101-L103 PolarHBondContact O-N 3.26Å; L103-L107 VanDerWaalsContact O-CB 3.27Å; L103-L107 WeakPolarHBondContact O-CB 3.48Å; L103-L107 PolarHBondContact O-N 3.25Å; L103-Y108 HydrophobicContact CD2-CD2 3.72Å; L103-Y108 HydrophobicContact CD2-CE1 4.42Å; L103-Y108 HydrophobicContact CD2-CE2 3.05Å; L103-Y108 VanDerWaalsContact CD2-CZ 3.46Å; L103-Y108 HydrophobicContact CG-CE2 4.19Å; L103-Y108 PolarHBondContact O-N 2.97Å
104T85.2Confident82.1Confident81 Ų8156.1 Ų56.150%0.49733%0.326SS..Iπ-helixtrans-68.1-48.6175.5-51.20000112.1A101 Y108 L109A101-T104 PolarHBondContact O-N 3.26Å; T104-Y108 PolarHBondContact O-N 3.42Å; T104-L109 PolarHBondContact O-N 2.95Å
105L86.3Confident82.2Confident108 Ų10859.8 Ų59.857%0.56534%0.342SS*.Iπ-helixtrans-80.2-39.5-171.8-66.9174.9000114A101 L109 P110A101-L105 HydrophobicContact CB-CD1 4.34Å; A101-L105 WeakPolarHBondContact O-CB 3.46Å; A101-L105 WeakPolarHBondContact O-CG 3.38Å; A101-L105 PolarHBondContact O-N 3.42Å; L105-L109 HydrophobicContact CD2-CD2 4.5Å; L105-P110 VanDerWaalsContact O-CD 3.29Å; L105-P110 WeakPolarHBondContact O-CD 3.39Å
106S81.4Confident82.8Confident17 Ų1766.1 Ų66.112%0.11936%0.362CS..Iπ-helixtrans-95.3-17.1-173.4-53.90000113.6T67 R102T67-S106 WeakPolarHBondContact CB-OG 3.14Å; T67-S106 WeakPolarHBondContact CG2-OG 3.49Å; R102-S106 WeakPolarHBondContact O-CA 3.22Å; R102-S106 WeakPolarHBondContact O-CB 3.48Å; R102-S106 PolarHBondContact O-N 3.15Å; R102-S106 PolarHBondContact O-OG 3.21Å
107L76Confident83.3Confident6 Ų668.6 Ų68.63%0.03137%0.368CS..Iπ-helixtrans-113.4-68.9177.5-164.468.6000110.5Y64 L103 L109 P110 F111 Y524 R527Y64-L107 HydrophobicContact CD2-CB 4.3Å; Y64-L107 HydrophobicContact CE2-CB 4.05Å; L103-L107 VanDerWaalsContact O-CB 3.27Å; L103-L107 WeakPolarHBondContact O-CB 3.48Å; L103-L107 PolarHBondContact O-N 3.25Å; L107-L109 PolarHBondContact O-N 2.66Å; L107-P110 WeakPolarHBondContact O-CD 3.47Å; L107-F111 HydrophobicContact CD1-CD2 4.03Å; L107-F111 HydrophobicContact CD1-CE2 3.92Å; L107-F111 HydrophobicContact CG-CD2 4.19Å; L107-F111 WeakPolarHBondContact O-CD2 3.19Å; L107-F111 PolarHBondContact O-N 3.36Å; L107-F111 VanDerWaalsContact O-N 3.15Å; L107-Y524 HydrophobicContact CD1-CE1 4.17Å; L107-R527 VanDerWaalsContact CD1-NH1 3.34Å
108Y83.4Confident83.1Confident117 Ų11764.9 Ų64.946%0.45935%0.349SS..Iπ-helixtrans-65.5-37.7-168.8-63.1-28.7000113.8L103 T104 F111 A112L103-Y108 HydrophobicContact CD2-CD2 3.72Å; L103-Y108 HydrophobicContact CD2-CE1 4.42Å; L103-Y108 HydrophobicContact CD2-CE2 3.05Å; L103-Y108 VanDerWaalsContact CD2-CZ 3.46Å; L103-Y108 HydrophobicContact CG-CE2 4.19Å; L103-Y108 PolarHBondContact O-N 2.97Å; T104-Y108 PolarHBondContact O-N 3.42Å; Y108-F111 PolarHBondContact O-N 3.48Å; Y108-A112 VanDerWaalsContact O-CB 3.3Å; Y108-A112 WeakPolarHBondContact O-CB 3Å; Y108-A112 PolarHBondContact O-N 3.36Å
109L86.8Confident83.3Confident96 Ų9666 Ų6650%0.50336%0.358SS..Hα-helixtrans-64.2-51.9178.6-18069.1000112.7T104 L105 L107 F111 A112 V113T104-L109 PolarHBondContact O-N 2.95Å; L105-L109 HydrophobicContact CD2-CD2 4.5Å; L107-L109 PolarHBondContact O-N 2.66Å; L109-F111 VanDerWaalsContact C-N 3.27Å; L109-F111 PolarHBondContact O-N 3.49Å; L109-A112 PolarHBondContact O-N 3.03Å; L109-A112 VanDerWaalsContact O-N 3.17Å; L109-V113 WeakPolarHBondContact O-CG2 3.02Å; L109-V113 PolarHBondContact O-N 3.07Å
110P83.4Confident83.9Confident47 Ų4766.1 Ų66.131%0.30536%0.362SS..Hα-helixtrans-55-40171.8-28.733.5000113.8V60 L105 L107 V113 Q114V60-P110 HydrophobicContact CG1-CB 4.43Å; L105-P110 VanDerWaalsContact O-CD 3.29Å; L105-P110 WeakPolarHBondContact O-CD 3.39Å; L107-P110 WeakPolarHBondContact O-CD 3.47Å; P110-V113 PolarHBondContact O-N 3.22Å; P110-Q114 WeakPolarHBondContact O-CB 3.47Å; P110-Q114 PolarHBondContact O-N 3.19Å
111F78.5Confident84.1Confident42 Ų4265.1 Ų65.118%0.18435%0.348CS..Hα-helixtrans-66.5-40.5176.3-87.7-71.2000112.9L107 Y108 L109 Q114 N115 Y524L107-F111 HydrophobicContact CD1-CD2 4.03Å; L107-F111 HydrophobicContact CD1-CE2 3.92Å; L107-F111 HydrophobicContact CG-CD2 4.19Å; L107-F111 WeakPolarHBondContact O-CD2 3.19Å; L107-F111 PolarHBondContact O-N 3.36Å; L107-F111 VanDerWaalsContact O-N 3.15Å; Y108-F111 PolarHBondContact O-N 3.48Å; L109-F111 VanDerWaalsContact C-N 3.27Å; L109-F111 PolarHBondContact O-N 3.49Å; F111-Q114 PolarHBondContact O-N 2.82Å; F111-N115 WeakPolarHBondContact O-CB 3.26Å; F111-N115 VanDerWaalsContact O-CG 3.22Å; F111-N115 PolarHBondContact O-N 3.23Å; F111-Y524 HydrophobicContact CE2-CE1 4.41Å; F111-Y524 AromaticContact CE2-CZ 3.83Å; F111-Y524 WeakPolarHBondContact CE2-OH 3.43Å; F111-Y524 HydrophobicContact CZ-CE2 4.25Å; F111-Y524 AromaticContact CZ-CZ 3.64Å; F111-Y524 WeakPolarHBondContact CZ-OH 3.2Å
112A87.8Confident84.2Confident56 Ų5666.7 Ų66.746%0.46335%0.354SS..Hα-helixtrans-63.9-43.4176.800000111.3Y108 L109 N115 Y116Y108-A112 VanDerWaalsContact O-CB 3.3Å; Y108-A112 WeakPolarHBondContact O-CB 3Å; Y108-A112 PolarHBondContact O-N 3.36Å; L109-A112 PolarHBondContact O-N 3.03Å; L109-A112 VanDerWaalsContact O-N 3.17Å; A112-N115 PolarHBondContact O-N 3.38Å; A112-Y116 WeakPolarHBondContact O-CB 3.45Å; A112-Y116 PolarHBondContact O-N 3.09Å
113V88Confident84.5Confident77 Ų7770.3 Ų70.347%0.46737%0.374SS..Hα-helixtrans-63.2-44.2174.6175.50000110.8L109 P110 Y116 L117L109-V113 WeakPolarHBondContact O-CG2 3.02Å; L109-V113 PolarHBondContact O-N 3.07Å; P110-V113 PolarHBondContact O-N 3.22Å; V113-Y116 PolarHBondContact O-N 3.05Å; V113-L117 HydrophobicContact CG1-CD1 4.17Å; V113-L117 VanDerWaalsContact O-CG 3.3Å; V113-L117 WeakPolarHBondContact O-CG 3.34Å; V113-L117 PolarHBondContact O-N 3.46Å
114Q81.9Confident85Confident37 Ų3772 Ų7217%0.17338%0.384CS..Hα-helixtrans-58.7-51.1176.2-176.7-175.3-38.700111.2P110 F111 Y116 L117 E118P110-Q114 WeakPolarHBondContact O-CB 3.47Å; P110-Q114 PolarHBondContact O-N 3.19Å; F111-Q114 PolarHBondContact O-N 2.82Å; Q114-Y116 VanDerWaalsContact C-N 3.32Å; Q114-Y116 PolarHBondContact O-N 2.81Å; Q114-L117 PolarHBondContact O-N 3.42Å; Q114-E118 VanDerWaalsContact CG-OE1 3.3Å; Q114-E118 WeakPolarHBondContact CG-OE1 3.49Å; Q114-E118 PolarHBondContact NE2-OE1 2.65Å; Q114-E118 WeakPolarHBondContact O-CG 3.46Å; Q114-E118 PolarHBondContact O-N 3.13Å
115N83.3Confident84.9Confident90 Ų9072.7 Ų72.748%0.48138%0.377SS..Hα-helixtrans-64.1-36.2-179.4-70.5-8.3000112F111 A112 E118 L119F111-N115 WeakPolarHBondContact O-CB 3.26Å; F111-N115 VanDerWaalsContact O-CG 3.22Å; F111-N115 PolarHBondContact O-N 3.23Å; A112-N115 PolarHBondContact O-N 3.38Å; N115-E118 PolarHBondContact O-N 3.37Å; N115-L119 WeakPolarHBondContact O-CB 3.35Å; N115-L119 PolarHBondContact O-N 3.09Å
116Y90.6Very high84.9Confident155 Ų15571.3 Ų71.361%0.60837%0.369SS*.Hα-helixtrans-64.5-42.8174.3176.5-99.1000112A112 V113 Q114 L119 S120A112-Y116 WeakPolarHBondContact O-CB 3.45Å; A112-Y116 PolarHBondContact O-N 3.09Å; V113-Y116 PolarHBondContact O-N 3.05Å; Q114-Y116 VanDerWaalsContact C-N 3.32Å; Q114-Y116 PolarHBondContact O-N 2.81Å; Y116-L119 PolarHBondContact O-N 2.91Å; Y116-S120 WeakPolarHBondContact O-CB 3.43Å; Y116-S120 PolarHBondContact O-N 3.37Å; Y116-S120 PolarHBondContact O-OG 3.35Å
117L86.6Confident85.3Confident99 Ų9975.8 Ų75.852%0.51839%0.389SS..Hα-helixtrans-65.1-41.4176.2-69.2173.5000111.6V113 Q114 S120 V121V113-L117 HydrophobicContact CG1-CD1 4.17Å; V113-L117 VanDerWaalsContact O-CG 3.3Å; V113-L117 WeakPolarHBondContact O-CG 3.34Å; V113-L117 PolarHBondContact O-N 3.46Å; Q114-L117 PolarHBondContact O-N 3.42Å; L117-S120 PolarHBondContact O-N 2.95Å; L117-V121 WeakPolarHBondContact O-CG2 3.44Å; L117-V121 PolarHBondContact O-N 3.09Å
118E80.8Confident85.6Confident52 Ų5279.7 Ų79.724%0.24341%0.412CS..Hα-helixtrans-65.3-42.7175.2-74175.1-156.900112.1W2 Q114 N115 V121 T122W2-E118 HydrophobicContact CD2-CG 4.39Å; W2-E118 HydrophobicContact CG-CG 4.26Å; W2-E118 WeakPolarHBondContact CZ2-OE1 3.27Å; W2-E118 PolarHBondContact NE1-OE1 3.36Å; W2-E118 VanDerWaalsContact NE1-OE1 3.12Å; Q114-E118 VanDerWaalsContact CG-OE1 3.3Å; Q114-E118 WeakPolarHBondContact CG-OE1 3.49Å; Q114-E118 PolarHBondContact NE2-OE1 2.65Å; Q114-E118 WeakPolarHBondContact O-CG 3.46Å; Q114-E118 PolarHBondContact O-N 3.13Å; N115-E118 PolarHBondContact O-N 3.37Å; E118-V121 PolarHBondContact O-N 3.46Å; E118-T122 WeakPolarHBondContact O-CB 3.36Å; E118-T122 PolarHBondContact O-N 2.99Å; E118-T122 PolarHBondContact O-OG1 2.66Å
119L89.7Confident85.2Confident93 Ų9377.7 Ų77.749%0.48742%0.416SS..Hα-helixtrans-62.3-44.9174.9178.863.2000111.2N115 Y116 V121 T122 L123N115-L119 WeakPolarHBondContact O-CB 3.35Å; N115-L119 PolarHBondContact O-N 3.09Å; Y116-L119 PolarHBondContact O-N 2.91Å; L119-V121 VanDerWaalsContact C-N 3.31Å; L119-V121 PolarHBondContact O-N 3.33Å; L119-T122 PolarHBondContact O-N 3.26Å; L119-T122 VanDerWaalsContact O-N 3.15Å; L119-L123 HydrophobicContact CD1-CD1 4.05Å; L119-L123 HydrophobicContact CD1-CD2 4.43Å; L119-L123 HydrophobicContact CD1-CG 3.92Å; L119-L123 HydrophobicContact CD2-CD1 4.41Å; L119-L123 HydrophobicContact CG-CD1 3.84Å; L119-L123 HydrophobicContact CG-CG 4.16Å; L119-L123 WeakPolarHBondContact O-CB 3.34Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 2.83Å
120S89.1Confident84.7Confident35 Ų3579.9 Ų79.925%0.24542%0.421CS..Hα-helixtrans-59.8-41.9179.5-59.80000111.7Y116 L117 N124Y116-S120 WeakPolarHBondContact O-CB 3.43Å; Y116-S120 PolarHBondContact O-N 3.37Å; Y116-S120 PolarHBondContact O-OG 3.35Å; L117-S120 PolarHBondContact O-N 2.95Å; S120-N124 WeakPolarHBondContact O-CB 3.48Å; S120-N124 VanDerWaalsContact O-CG 3.26Å; S120-N124 PolarHBondContact O-N 3.36Å; S120-N124 PolarHBondContact O-ND2 3.36Å
121V83.6Confident84.3Confident44 Ų4482.6 Ų82.627%0.26743%0.433SS..Hα-helixtrans-67.1-42.5175.4173.70000111.2F3 L117 E118 L119 N124 R125F3-V121 HydrophobicContact CD2-CG1 4.06Å; L117-V121 WeakPolarHBondContact O-CG2 3.44Å; L117-V121 PolarHBondContact O-N 3.09Å; E118-V121 PolarHBondContact O-N 3.46Å; L119-V121 VanDerWaalsContact C-N 3.31Å; L119-V121 PolarHBondContact O-N 3.33Å; V121-N124 PolarHBondContact O-N 3.29Å; V121-R125 WeakPolarHBondContact O-CG 3.18Å; V121-R125 PolarHBondContact O-N 2.86Å
122T86.6Confident83.7Confident72 Ų7287.3 Ų87.344%0.44246%0.456SS..Hα-helixtrans-64.4-43.7178.6-570000111.6E118 L119 R125 I126E118-T122 WeakPolarHBondContact O-CB 3.36Å; E118-T122 PolarHBondContact O-N 2.99Å; E118-T122 PolarHBondContact O-OG1 2.66Å; L119-T122 PolarHBondContact O-N 3.26Å; L119-T122 VanDerWaalsContact O-N 3.15Å; T122-R125 WeakPolarHBondContact O-CB 3.47Å; T122-R125 PolarHBondContact O-N 3.1Å; T122-I126 HydrophobicContact CG2-CD1 3.9Å; T122-I126 HydrophobicContact CG2-CG1 4.49Å; T122-I126 WeakPolarHBondContact O-CG1 3.36Å; T122-I126 PolarHBondContact O-N 2.89Å
123L90.1Very high82.3Confident90 Ų9087.8 Ų87.847%0.47146%0.455SS..Hα-helixtrans-62.7-43.4175.8-73.2175.1000111.6L119 R125 I126 Q127L119-L123 HydrophobicContact CD1-CD1 4.05Å; L119-L123 HydrophobicContact CD1-CD2 4.43Å; L119-L123 HydrophobicContact CD1-CG 3.92Å; L119-L123 HydrophobicContact CD2-CD1 4.41Å; L119-L123 HydrophobicContact CG-CD1 3.84Å; L119-L123 HydrophobicContact CG-CG 4.16Å; L119-L123 WeakPolarHBondContact O-CB 3.34Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 2.83Å; L123-R125 VanDerWaalsContact C-N 3.31Å; L123-R125 PolarHBondContact O-N 2.91Å; L123-I126 PolarHBondContact O-N 3.16Å; L123-Q127 VanDerWaalsContact O-CB 3.32Å; L123-Q127 WeakPolarHBondContact O-CB 3.4Å; L123-Q127 PolarHBondContact O-N 3.29Å
124N87Confident80.8Confident99 Ų9986.8 Ų86.853%0.52946%0.455SS..Hα-helixtrans-59.8-41.3174.4-75.8-17.5000111.8S120 V121 Q127 V128S120-N124 WeakPolarHBondContact O-CB 3.48Å; S120-N124 VanDerWaalsContact O-CG 3.26Å; S120-N124 PolarHBondContact O-N 3.36Å; S120-N124 PolarHBondContact O-ND2 3.36Å; V121-N124 PolarHBondContact O-N 3.29Å; N124-Q127 PolarHBondContact O-N 2.92Å; N124-V128 VanDerWaalsContact O-CG2 3.31Å; N124-V128 WeakPolarHBondContact O-CG2 3.42Å; N124-V128 PolarHBondContact O-N 3.4Å
125R81.8Confident79.2Confident94 Ų9492.9 Ų92.936%0.35549%0.485SS..Hα-helixtrans-63.3-46.2175.5-73.8176.9172.2-147.2-9.2111.7A6 D10 V121 T122 L123 V128 S129A6-R125 VanDerWaalsContact CB-NH2 3.34Å; D10-R125 IonicContact OD2-CZ 3.55Å; D10-R125 IonicContact OD2-NH1 2.94Å; D10-R125 PolarHBondContact OD2-NH1 3.36Å; D10-R125 VanDerWaalsContact OD2-NH1 3.09Å; D10-R125 IonicContact OD2-NH2 3.87Å; D10-R125 PolarHBondContact OD2-NH2 3.25Å; V121-R125 WeakPolarHBondContact O-CG 3.18Å; V121-R125 PolarHBondContact O-N 2.86Å; T122-R125 WeakPolarHBondContact O-CB 3.47Å; T122-R125 PolarHBondContact O-N 3.1Å; L123-R125 VanDerWaalsContact C-N 3.31Å; L123-R125 PolarHBondContact O-N 2.91Å; R125-V128 PolarHBondContact O-N 3.08Å; R125-S129 PolarHBondContact O-N 3.48Å; R125-S129 VanDerWaalsContact O-N 3.1Å
126I87.4Confident77.7Confident79 Ų7992.7 Ų92.741%0.40548%0.484SS..Hα-helixtrans-61.6-44177.7-71.5170.6000110.6T122 L123 S129 F130T122-I126 HydrophobicContact CG2-CD1 3.9Å; T122-I126 HydrophobicContact CG2-CG1 4.49Å; T122-I126 WeakPolarHBondContact O-CG1 3.36Å; T122-I126 PolarHBondContact O-N 2.89Å; L123-I126 PolarHBondContact O-N 3.16Å; I126-S129 WeakPolarHBondContact O-CB 3.44Å; I126-S129 PolarHBondContact O-N 3.14Å; I126-F130 HydrophobicContact CG2-CD2 3.45Å; I126-F130 VanDerWaalsContact CG2-CD2 3.45Å; I126-F130 HydrophobicContact CG2-CE2 3.37Å; I126-F130 VanDerWaalsContact O-CD2 3.28Å; I126-F130 WeakPolarHBondContact O-CD2 3.38Å; I126-F130 PolarHBondContact O-N 3.3Å
127Q88.2Confident75.5Confident112 Ų11291.9 Ų91.952%0.52349%0.49SS..Hα-helixtrans-62.4-43.5178.4-176.1179.1-4.300112.3L123 N124 S129 F130 N131L123-Q127 VanDerWaalsContact O-CB 3.32Å; L123-Q127 WeakPolarHBondContact O-CB 3.4Å; L123-Q127 PolarHBondContact O-N 3.29Å; N124-Q127 PolarHBondContact O-N 2.92Å; Q127-S129 VanDerWaalsContact C-N 3.29Å; Q127-S129 PolarHBondContact O-N 2.72Å; Q127-F130 PolarHBondContact O-N 2.81Å; Q127-N131 WeakPolarHBondContact O-CB 3.37Å; Q127-N131 VanDerWaalsContact O-CG 3.28Å; Q127-N131 PolarHBondContact O-N 3Å
128V82.1Confident73.3Confident87 Ų8796.1 Ų96.153%0.52750%0.504SS..Hα-helixtrans-60.2-41.9174.6171.10000110.8N124 R125 N131 H132N124-V128 VanDerWaalsContact O-CG2 3.31Å; N124-V128 WeakPolarHBondContact O-CG2 3.42Å; N124-V128 PolarHBondContact O-N 3.4Å; R125-V128 PolarHBondContact O-N 3.08Å; V128-N131 PolarHBondContact O-N 2.88Å; V128-H132 PolarHBondContact O-CD2 2.95Å; V128-H132 PolarHBondContact O-N 3.31Å
129S75.5Confident71.3Confident76 Ų7698.8 Ų98.853%0.53152%0.52SS..Hα-helixtrans-62.6-47.6176.5-162.90000112.2R125 I126 Q127 N131 H132 S133R125-S129 PolarHBondContact O-N 3.48Å; R125-S129 VanDerWaalsContact O-N 3.1Å; I126-S129 WeakPolarHBondContact O-CB 3.44Å; I126-S129 PolarHBondContact O-N 3.14Å; Q127-S129 VanDerWaalsContact C-N 3.29Å; Q127-S129 PolarHBondContact O-N 2.72Å; S129-N131 PolarHBondContact O-N 2.85Å; S129-H132 PolarHBondContact O-N 3.44Å; S129-S133 PolarHBondContact O-N 3.31Å; S129-S133 PolarHBondContact O-OG 3.35Å
130F77.3Confident68.9Low142 Ų142100.4 Ų100.462%0.62353%0.534SS*.Hα-helixtrans-62.7-38.9177.5-85.8-68.2000113I126 Q127 H132 S133 A134I126-F130 HydrophobicContact CG2-CD2 3.45Å; I126-F130 VanDerWaalsContact CG2-CD2 3.45Å; I126-F130 HydrophobicContact CG2-CE2 3.37Å; I126-F130 VanDerWaalsContact O-CD2 3.28Å; I126-F130 WeakPolarHBondContact O-CD2 3.38Å; I126-F130 PolarHBondContact O-N 3.3Å; Q127-F130 PolarHBondContact O-N 2.81Å; F130-H132 VanDerWaalsContact C-N 3.29Å; F130-H132 PolarHBondContact O-N 3.14Å; F130-S133 PolarHBondContact O-N 3.49Å; F130-A134 WeakPolarHBondContact O-CB 3.46Å; F130-A134 PolarHBondContact O-N 3.16Å
131N73.6Confident66.4Low104 Ų104103.3 Ų103.356%0.55655%0.546SS*.Hα-helixtrans-62.8-36177.5-74.9-10.5000112.1Q127 V128 S129Q127-N131 WeakPolarHBondContact O-CB 3.37Å; Q127-N131 VanDerWaalsContact O-CG 3.28Å; Q127-N131 PolarHBondContact O-N 3Å; V128-N131 PolarHBondContact O-N 2.88Å; S129-N131 PolarHBondContact O-N 2.85Å
132H66.4Low64Low141 Ų141110 Ų11065%0.65357%0.572SS**Hα-helixtrans-68-41.8174.3-89.9-72.9000112.5V128 S129 F130V128-H132 PolarHBondContact O-CD2 2.95Å; V128-H132 PolarHBondContact O-N 3.31Å; S129-H132 PolarHBondContact O-N 3.44Å; F130-H132 VanDerWaalsContact C-N 3.29Å; F130-H132 PolarHBondContact O-N 3.14Å
133S59.6Low61.7Low65 Ų65114 Ų11446%0.45558%0.583SS.*Hα-helixtrans-70.6-32.7179.1-58.80000113.7S129 F130 M135 I136S129-S133 PolarHBondContact O-N 3.31Å; S129-S133 PolarHBondContact O-OG 3.35Å; F130-S133 PolarHBondContact O-N 3.49Å; S133-M135 PolarHBondContact O-N 2.92Å; S133-I136 PolarHBondContact O-N 2.87Å; S133-I136 VanDerWaalsContact O-N 3.16Å
134A55.2Low59Low56 Ų56119 Ų11946%0.46360%0.596SS.*Hα-helixtrans-62.9-26-179.600000113.2F130 I136F130-A134 WeakPolarHBondContact O-CB 3.46Å; F130-A134 PolarHBondContact O-N 3.16Å; A134-I136 PolarHBondContact O-N 3.39Å
135M48.9Very low56.3Low165 Ų165121.9 Ų121.981%0.81361%0.611SS**THydrogen-bonded Turntrans-66.5-21.4177.4-110.7-173153.100113.6S133S133-M135 PolarHBondContact O-N 2.92Å
136I51.4Low54.1Low87 Ų87124.9 Ų124.945%0.44663%0.627SS.*THydrogen-bonded Turntrans-89.2-22.3-173.3-60173.8000111.9S133 A134S133-I136 PolarHBondContact O-N 2.87Å; S133-I136 VanDerWaalsContact O-N 3.16Å; A134-I136 PolarHBondContact O-N 3.39Å
137N44.2Very low51.6Low138 Ų138131.2 Ų131.274%0.73865%0.647SS**  trans-105.213-161.6-86.7-19.1000118.2
138F40Very low49.1Very low187 Ų187127.9 Ų127.982%0.8264%0.636SS**  trans-105.269.2179-90.4-83.5000113.8
139L40Very low47.2Very low108 Ų108124.9 Ų124.957%0.56562%0.618SS**  trans-129.289.4158.1-87164.5000109.4L141L139-L141 PolarHBondContact O-N 3.45Å
140T38.3Very low45.3Very low127 Ų127129.3 Ų129.378%0.77962%0.623SS**  trans-54.4119.1175.442.60000111.9K142T140-K142 PolarHBondContact O-N 3.04Å
141L36.3Very low43.3Very low96 Ų96129.2 Ų129.250%0.50362%0.623SS.*  trans-65111.6166-89.1152000109.8L139 F143L139-L141 PolarHBondContact O-N 3.45Å; L141-F143 HydrophobicContact CB-CD2 4.01Å; L141-F143 HydrophobicContact CB-CE2 3.82Å; L141-F143 HydrophobicContact CD1-CE2 3.87Å; L141-F143 HydrophobicContact CD1-CZ 3.93Å; L141-F143 HydrophobicContact CD2-CE1 4.34Å; L141-F143 HydrophobicContact CD2-CE2 4.16Å; L141-F143 HydrophobicContact CD2-CZ 4.06Å; L141-F143 HydrophobicContact CG-CE2 4.17Å; L141-F143 HydrophobicContact CG-CZ 4.4Å
142K35Very low42.1Very low185 Ų185124.3 Ų124.380%0.80460%0.597SS**  trans-86.798.2150.9-81.6-174.4179175.30107.2T140 R144T140-K142 PolarHBondContact O-N 3.04Å; K142-R144 PolarHBondContact O-N 3.27Å; K142-R144 VanDerWaalsContact O-N 3.15Å
143F36.7Very low40.5Very low157 Ų157120.3 Ų120.369%0.68958%0.583SS**  trans-63.6113.3165.8-76.4-84000108.6L141L141-F143 HydrophobicContact CB-CD2 4.01Å; L141-F143 HydrophobicContact CB-CE2 3.82Å; L141-F143 HydrophobicContact CD1-CE2 3.87Å; L141-F143 HydrophobicContact CD1-CZ 3.93Å; L141-F143 HydrophobicContact CD2-CE1 4.34Å; L141-F143 HydrophobicContact CD2-CE2 4.16Å; L141-F143 HydrophobicContact CD2-CZ 4.06Å; L141-F143 HydrophobicContact CG-CE2 4.17Å; L141-F143 HydrophobicContact CG-CZ 4.4Å
144R34Very low39.7Very low194 Ų194117.3 Ų117.373%0.73256%0.561SS**  trans-118.2134.2162.3-86.2-174166.8179.4-4107.7K142 F146K142-R144 PolarHBondContact O-N 3.27Å; K142-R144 VanDerWaalsContact O-N 3.15Å; R144-F146 VanDerWaalsContact C-N 3.29Å; R144-F146 PolarHBondContact O-N 2.79Å
145N30Very low38.8Very low159 Ų159118.5 Ų118.585%0.8556%0.556SS**SBendtrans-66.282.9177.6-67.6-14.3000110.7
146F36Very low38.3Very low157 Ų157112.1 Ų112.169%0.68952%0.524SS*.  trans-146.3121.2166.2-79.2-78.9000109.3R144 C148 N208R144-F146 VanDerWaalsContact C-N 3.29Å; R144-F146 PolarHBondContact O-N 2.79Å; F146-C148 PolarHBondContact O-N 3.11Å; F146-C148 VanDerWaalsContact O-N 3.16Å; F146-N208 PolarHBondContact O-ND2 3.02Å
147Y35.6Very low37.6Very low212 Ų212110.7 Ų110.783%0.83153%0.525SS*.  trans-80.282.1173.6-60.4-88.5000109.1
148C35.7Very low37.2Very low42 Ų42111.3 Ų111.328%0.28452%0.521SS..  trans-164.9122173.6-163.50000110.5F146 R150F146-C148 PolarHBondContact O-N 3.11Å; F146-C148 VanDerWaalsContact O-N 3.16Å; C148-R150 PolarHBondContact O-N 3.4Å
149C41.9Very low37.2Very low24 Ų24110.4 Ų110.416%0.16253%0.525CS..BIsolated β-bridgetrans-77.4105.1162.8-86.60000108S170 V206C149-S170 WeakPolarHBondContact O-CA 3.24Å; C149-S170 WeakPolarHBondContact O-CB 3.38Å; C149-V206 PolarHBondContact SG-O 3.49Å
150R35.3Very low37.2Very low169 Ų169111.7 Ų111.764%0.63854%0.537SS*.  trans-109.7126.8-179.9-102.2177.4-177.41731.4111.7C148C148-R150 PolarHBondContact O-N 3.4Å
151F36Very low37.1Very low141 Ų141114 Ų11462%0.61854%0.536SS*.  trans47.5112.5162.6-54.5-72.6000118T168F151-T168 HydrophobicContact CD1-CG2 4.43Å
152F47.2Very low37Very low1 Ų1114.6 Ų114.60%0.00454%0.54CS..  trans-109145.7168.3-52.9-76.3000111.1I154 V167 T168 F169 L194 E204 V205F152-I154 HydrophobicContact CB-CD1 4.46Å; F152-I154 HydrophobicContact CB-CG1 4.39Å; F152-V167 CarbonylContact C-O 3.57Å; F152-T168 WeakPolarHBondContact O-CA 3.42Å; F152-T168 WeakPolarHBondContact O-CB 3.48Å; F152-T168 VanDerWaalsContact O-CG2 3.24Å; F152-T168 WeakPolarHBondContact O-CG2 3.39Å; F152-T168 PolarHBondContact O-OG1 3.22Å; F152-F169 HydrophobicContact CD2-CD1 4.12Å; F152-F169 AromaticContact CD2-CE1 3.97Å; F152-F169 HydrophobicContact CD2-CE1 3.97Å; F152-F169 HydrophobicContact CD2-CE2 4.44Å; F152-F169 HydrophobicContact CD2-CG 4.42Å; F152-F169 HydrophobicContact CD2-CZ 4.14Å; F152-F169 VanDerWaalsContact CD2-O 3.22Å; F152-F169 WeakPolarHBondContact CD2-O 3.25Å; F152-F169 HydrophobicContact CE2-CD2 4.49Å; F152-F169 HydrophobicContact CE2-CE1 4.39Å; F152-F169 HydrophobicContact CE2-CE2 4.14Å; F152-F169 HydrophobicContact CE2-CZ 4.09Å; F152-L194 HydrophobicContact CE1-CD2 4.18Å; F152-L194 HydrophobicContact CE2-CD2 4.35Å; F152-L194 HydrophobicContact CZ-CD2 3.88Å; F152-E204 VanDerWaalsContact CD1-O 3.31Å; F152-E204 WeakPolarHBondContact CD1-O 3.34Å; F152-V205 HydrophobicContact CD1-CB 4.08Å; F152-V205 HydrophobicContact CD1-CG1 4.23Å; F152-V205 HydrophobicContact CD1-CG2 3.77Å; F152-V205 VanDerWaalsContact CE1-CA 3.48Å; F152-V205 HydrophobicContact CE1-CB 3.88Å; F152-V205 HydrophobicContact CE1-CG1 3.64Å; F152-V205 HydrophobicContact CE1-CG2 4.05Å
153T33.7Very low37.6Very low57 Ų57112 Ų11235%0.3553%0.53SS..  trans-140.692.3155-54.70000105.3F155 V167 K202 G203T153-F155 HydrophobicContact CG2-CD2 4.05Å; T153-F155 HydrophobicContact CG2-CE2 3.37Å; T153-F155 HydrophobicContact CG2-CZ 3.82Å; T153-V167 WeakPolarHBondContact CA-O 3.29Å; T153-K202 CarbonylContact O-C 3.53Å; T153-G203 WeakPolarHBondContact O-CA 3.3Å; T153-G203 PolarHBondContact O-N 2.72Å
154I42Very low37.9Very low2 Ų2110.2 Ų110.21%0.0153%0.527CS..  trans-83.5126.2-176.9-62.3159.5000108.2F152 F156 T193 H200 V205F152-I154 HydrophobicContact CB-CD1 4.46Å; F152-I154 HydrophobicContact CB-CG1 4.39Å; I154-F156 HydrophobicContact CB-CE2 4.36Å; I154-F156 HydrophobicContact CB-CZ 4.4Å; I154-F156 HydrophobicContact CG2-CD1 4.3Å; I154-F156 HydrophobicContact CG2-CD2 4.12Å; I154-F156 HydrophobicContact CG2-CE1 3.77Å; I154-F156 HydrophobicContact CG2-CE2 3.57Å; I154-F156 HydrophobicContact CG2-CG 4.46Å; I154-F156 HydrophobicContact CG2-CZ 3.37Å; I154-T193 HydrophobicContact CD1-CG2 3.64Å; I154-T193 HydrophobicContact CG1-CG2 4.09Å; I154-T193 HydrophobicContact CG2-CG2 4.22Å; I154-H200 HydrophobicContact CG2-CB 3.75Å; I154-V205 HydrophobicContact CG1-CG2 4.5Å
155F37.3Very low38.8Very low81 Ų81103.7 Ų103.736%0.35551%0.508SS..BIsolated β-bridgetrans-111.3114166.9-64.8-97.1000109.3T153 N201 K202T153-F155 HydrophobicContact CG2-CD2 4.05Å; T153-F155 HydrophobicContact CG2-CE2 3.37Å; T153-F155 HydrophobicContact CG2-CZ 3.82Å; F155-N201 PolarHBondContact O-N 2.84Å; F155-K202 HydrophobicContact CB-CB 3.99Å; F155-K202 HydrophobicContact CD2-CB 3.41Å; F155-K202 VanDerWaalsContact CD2-CB 3.41Å; F155-K202 HydrophobicContact CD2-CD 4.19Å; F155-K202 HydrophobicContact CD2-CG 4.4Å; F155-K202 HydrophobicContact CE2-CB 4.14Å; F155-K202 HydrophobicContact CE2-CD 4.48Å; F155-K202 HydrophobicContact CG-CB 3.99Å; F155-K202 HydrophobicContact CG-CD 4.41Å; F155-K202 PolarHBondContact N-O 2.98Å
156F38.3Very low40.1Very low31 Ų31100 Ų10014%0.13650%0.495CS..  trans-77.5134.1170.3-59.2-78.1000109.7I154 M189 V198I154-F156 HydrophobicContact CB-CE2 4.36Å; I154-F156 HydrophobicContact CB-CZ 4.4Å; I154-F156 HydrophobicContact CG2-CD1 4.3Å; I154-F156 HydrophobicContact CG2-CD2 4.12Å; I154-F156 HydrophobicContact CG2-CE1 3.77Å; I154-F156 HydrophobicContact CG2-CE2 3.57Å; I154-F156 HydrophobicContact CG2-CG 4.46Å; I154-F156 HydrophobicContact CG2-CZ 3.37Å; F156-M189 HydrophobicContact CD1-CE 3.53Å; F156-M189 HydrophobicContact CD1-CG 4.36Å; F156-M189 HydrophobicContact CD1-SD 3.65Å; F156-M189 HydrophobicContact CD2-CE 3.43Å; F156-M189 VanDerWaalsContact CD2-CE 3.43Å; F156-M189 HydrophobicContact CE1-CE 3.37Å; F156-M189 HydrophobicContact CE1-CG 3.61Å; F156-M189 HydrophobicContact CE1-SD 3.5Å; F156-M189 WeakPolarHBondContact CE1-SD 3.46Å; F156-M189 HydrophobicContact CE2-CE 3.26Å; F156-M189 HydrophobicContact CE2-SD 4.48Å; F156-M189 HydrophobicContact CG-CE 3.57Å; F156-M189 HydrophobicContact CG-SD 4.23Å; F156-M189 HydrophobicContact CZ-CE 3.23Å; F156-M189 HydrophobicContact CZ-CG 3.88Å; F156-M189 HydrophobicContact CZ-SD 3.95Å; F156-V198 HydrophobicContact CD1-CG1 4.05Å; F156-V198 HydrophobicContact CE1-CG1 3.77Å
157A37.2Very low41.3Very low57 Ų5793.7 Ų93.747%0.47147%0.469SS..  trans-105.7138.6175.500000112.6N201A157-N201 HydrophobicContact CB-CB 4.05Å; A157-N201 WeakPolarHBondContact CB-ND2 3.5Å
158K34.1Very low42.7Very low150 Ų15087.6 Ų87.665%0.65245%0.454SS*.  trans-54127.6-175.8-82.5171.1164.3176.10113.9
159D41.4Very low44.3Very low168 Ų16887.7 Ų87.790%0.89845%0.45SS*.SBendtrans-135.9-5.1131.2-96.1-29.2000114
160V39.9Very low45.5Very low135 Ų13589.7 Ų89.782%0.81846%0.464SS*.SBendtrans-141.7119.8171.1-168.90000108.7
161K35.3Very low47.2Very low176 Ų17683.3 Ų83.377%0.76544%0.444SS*.SBendtrans0.2113.1177.4-71.4177.4174179.20118.6
162D35.2Very low49Very low108 Ų10882.3 Ų82.358%0.57844%0.441SS*.  trans5760137.7-58.2-24.6000122.1
163H46.6Very low50.2Low130 Ų13086.9 Ų86.960%0.60247%0.471SS*.  trans-128.475.4155.4-62-51.2000111.8V165H163-V165 PolarHBondContact O-N 3.11Å
164I44Very low52Low121 Ų12187.2 Ų87.262%0.62149%0.486SS*.  trans-80.6101.9165.9-59.2172.2000106.8
165V52.2Low53.5Low56 Ų5692 Ų9234%0.33951%0.508SS..  trans-115.7105.3173.2-167.80000108.5H163 V167H163-V165 PolarHBondContact O-N 3.11Å; V165-V167 HydrophobicContact CB-CG2 4.18Å; V165-V167 HydrophobicContact CG1-CG2 3.42Å; V165-V167 VanDerWaalsContact CG1-CG2 3.42Å; V165-V167 PolarHBondContact O-N 3.48Å
166S56.5Low55.4Low81 Ų8192.8 Ų92.857%0.56652%0.515SS*.  trans-76105.2166.957.40000108.7
167V62.6Low57.3Low25 Ų2595.5 Ų95.515%0.15253%0.531CS..  trans-107.1128.6178.3-173.20000109.7F152 T153 V165 F169 I190F152-V167 CarbonylContact C-O 3.57Å; T153-V167 WeakPolarHBondContact CA-O 3.29Å; V165-V167 HydrophobicContact CB-CG2 4.18Å; V165-V167 HydrophobicContact CG1-CG2 3.42Å; V165-V167 VanDerWaalsContact CG1-CG2 3.42Å; V165-V167 PolarHBondContact O-N 3.48Å; V167-F169 HydrophobicContact CG1-CD1 3.8Å; V167-F169 HydrophobicContact CG1-CE1 4.05Å; V167-I190 HydrophobicContact CG1-CD1 4.27Å; V167-I190 HydrophobicContact CG2-CD1 4.05Å; V167-I190 HydrophobicContact CG2-CG1 4.36Å
168T64.2Low59.3Low85 Ų8595.4 Ų95.452%0.52153%0.53SS..  trans-132.6118.6176.2-54.20000110F151 F152F151-T168 HydrophobicContact CD1-CG2 4.43Å; F152-T168 WeakPolarHBondContact O-CA 3.42Å; F152-T168 WeakPolarHBondContact O-CB 3.48Å; F152-T168 VanDerWaalsContact O-CG2 3.24Å; F152-T168 WeakPolarHBondContact O-CG2 3.39Å; F152-T168 PolarHBondContact O-OG1 3.22Å
169F70.1Confident61.1Low43 Ų4391.3 Ų91.319%0.18952%0.515CS..  trans-151164171.166.3-81.9000110.2F152 V167 V171 L177 I190 L194F152-F169 HydrophobicContact CD2-CD1 4.12Å; F152-F169 AromaticContact CD2-CE1 3.97Å; F152-F169 HydrophobicContact CD2-CE1 3.97Å; F152-F169 HydrophobicContact CD2-CE2 4.44Å; F152-F169 HydrophobicContact CD2-CG 4.42Å; F152-F169 HydrophobicContact CD2-CZ 4.14Å; F152-F169 VanDerWaalsContact CD2-O 3.22Å; F152-F169 WeakPolarHBondContact CD2-O 3.25Å; F152-F169 HydrophobicContact CE2-CD2 4.49Å; F152-F169 HydrophobicContact CE2-CE1 4.39Å; F152-F169 HydrophobicContact CE2-CE2 4.14Å; F152-F169 HydrophobicContact CE2-CZ 4.09Å; V167-F169 HydrophobicContact CG1-CD1 3.8Å; V167-F169 HydrophobicContact CG1-CE1 4.05Å; F169-V171 HydrophobicContact CD2-CG2 3.68Å; F169-V171 HydrophobicContact CE2-CG2 3.82Å; F169-L177 HydrophobicContact CD2-CD2 3.58Å; F169-L177 HydrophobicContact CE2-CD2 3.6Å; F169-L177 HydrophobicContact CG-CD2 4.42Å; F169-L177 HydrophobicContact CZ-CD2 4.46Å; F169-I190 HydrophobicContact CE1-CG2 4.09Å; F169-I190 HydrophobicContact CZ-CG2 4.33Å; F169-L194 HydrophobicContact CZ-CD1 4.31Å; F169-L194 HydrophobicContact CZ-CD2 4.46Å
170S67.1Low62.5Low67 Ų6787.9 Ų87.947%0.46950%0.5SS..  trans-135.5144.3171.952.70000108.4C149C149-S170 WeakPolarHBondContact O-CA 3.24Å; C149-S170 WeakPolarHBondContact O-CB 3.38Å
171V71.5Confident63.5Low35 Ų3582.7 Ų82.721%0.21247%0.473CS..BIsolated β-bridgetrans-127.9127.9-179.1-171.30000108.4F169 Q175 L177F169-V171 HydrophobicContact CD2-CG2 3.68Å; F169-V171 HydrophobicContact CE2-CG2 3.82Å; V171-Q175 HydrophobicContact CG1-CB 4.04Å; V171-L177 HydrophobicContact CG2-CB 4.37Å; V171-L177 HydrophobicContact CG2-CD2 3.71Å
172E73.8Confident64.4Low120 Ų12079.1 Ų79.156%0.56147%0.468SS*.  trans-87.5152.1173.7-56.4-171.1153.200110.9G174 Q175E172-G174 PolarHBondContact O-N 3.28Å; E172-Q175 HydrophobicContact CB-CG 4.18Å; E172-Q175 WeakPolarHBondContact O-CB 3.4Å; E172-Q175 PolarHBondContact O-N 3.39Å
173P72.2Confident65.6Low97 Ų9779.3 Ų79.363%0.6347%0.469SS*.THydrogen-bonded Turntrans-55.7133177.3-24.134000112.2
174G70.8Confident66.1Low64 Ų6476.3 Ų76.366%0.6647%0.473SS*.THydrogen-bonded Turntrans86.42.7-179.600000115.3E172E172-G174 PolarHBondContact O-N 3.28Å
175Q74.1Confident67.2Low103 Ų10372.7 Ų72.748%0.48146%0.458SS..  trans-88.8137.8174.3-66.6-178.9-19.200112V171 E172V171-Q175 HydrophobicContact CG1-CB 4.04Å; E172-Q175 HydrophobicContact CB-CG 4.18Å; E172-Q175 WeakPolarHBondContact O-CB 3.4Å; E172-Q175 PolarHBondContact O-N 3.39Å
176L76.1Confident67.9Low96 Ų9671 Ų7150%0.50345%0.452SS..  trans-89.5115.9166.9177.465.4000109.3F310 Y315L176-F310 HydrophobicContact CD2-CE2 4.15Å; L176-F310 HydrophobicContact CD2-CZ 3.94Å; L176-Y315 HydrophobicContact CB-CD1 4.34Å; L176-Y315 HydrophobicContact CB-CG 4.27Å; L176-Y315 HydrophobicContact CD2-CG 4.47Å
177L78.5Confident68.7Low88 Ų8870.4 Ų70.446%0.46144%0.439SS..  trans-103.3123.1174.1-179.270.6000110.2F169 V171 I179F169-L177 HydrophobicContact CD2-CD2 3.58Å; F169-L177 HydrophobicContact CE2-CD2 3.6Å; F169-L177 HydrophobicContact CG-CD2 4.42Å; F169-L177 HydrophobicContact CZ-CD2 4.46Å; V171-L177 HydrophobicContact CG2-CB 4.37Å; V171-L177 HydrophobicContact CG2-CD2 3.71Å; L177-I179 HydrophobicContact CD2-CG1 4.41Å
178A78.9Confident69.4Low55 Ų5570.6 Ų70.646%0.45544%0.442SS..  trans-99.6125170.700000110.7V180A178-V180 HydrophobicContact CB-CG2 4.49Å
179I72.7Confident69.9Low64 Ų6469 Ų6933%0.32843%0.429SS..  trans-99.2109174.2-56.7177.1000108.7L177 K187 I190 L191L177-I179 HydrophobicContact CD2-CG1 4.41Å; I179-K187 HydrophobicContact CG2-CB 4.36Å; I179-K187 HydrophobicContact CG2-CG 4.04Å; I179-I190 HydrophobicContact CD1-CG2 4.1Å; I179-I190 HydrophobicContact CG2-CD1 4.37Å; I179-L191 HydrophobicContact CD1-CD2 4.25Å
180V69.6Low70.2Confident97 Ų9767.9 Ų67.959%0.58843%0.425SS*.  trans-110.6144.9-177.7-169.80000110.2A178A178-V180 HydrophobicContact CB-CG2 4.49Å
181G62.2Low70.9Confident25 Ų2565.4 Ų65.426%0.25841%0.406SS..  trans171.8162.4-179.600000112.3K187G181-K187 WeakPolarHBondContact O-CE 3.29Å; G181-K187 PolarHBondContact O-NZ 3.37Å
182P54.3Low71.4Confident101 Ų10167.4 Ų67.466%0.65641%0.413SS*.  trans-62.6161.718024.8-31.6000112G184 S185P182-G184 PolarHBondContact O-N 2.94Å; P182-S185 WeakPolarHBondContact O-CB 3.39Å; P182-S185 PolarHBondContact O-N 3.2Å; P182-S185 VanDerWaalsContact O-N 3.09Å; P182-S185 PolarHBondContact O-OG 2.88Å
183L59.2Low71.5Confident113 Ų11361.7 Ų61.759%0.59239%0.387SS*.THydrogen-bonded Turntrans-56.9133.1173.5-78.9130.9000110.1S185 D811L183-S185 VanDerWaalsContact C-N 3.33Å; L183-S185 PolarHBondContact O-N 2.74Å; L183-D811 HydrophobicContact CB-CB 4.4Å; L183-D811 HydrophobicContact CD1-CB 3.7Å
184G57.9Low71.7Confident67 Ų6758 Ų5869%0.69136%0.362SS*.THydrogen-bonded Turntrans79.93.9-176.100000115.7P182 G186P182-G184 PolarHBondContact O-N 2.94Å; G184-G186 PolarHBondContact O-N 3.37Å; G184-G186 VanDerWaalsContact O-N 3.12Å
185S66.2Low72.2Confident45 Ų4557.4 Ų57.432%0.31534%0.343SS..SBendtrans-68.1-4.3175.553.50000115.2P182 L183P182-S185 WeakPolarHBondContact O-CB 3.39Å; P182-S185 PolarHBondContact O-N 3.2Å; P182-S185 VanDerWaalsContact O-N 3.09Å; P182-S185 PolarHBondContact O-OG 2.88Å; L183-S185 VanDerWaalsContact C-N 3.33Å; L183-S185 PolarHBondContact O-N 2.74Å
186G66.6Low72.2Confident20 Ų2055.7 Ų55.721%0.20633%0.334CS..SBendtrans90.717179.300000115.3G184 S188 M189 I190G184-G186 PolarHBondContact O-N 3.37Å; G184-G186 VanDerWaalsContact O-N 3.12Å; G186-S188 PolarHBondContact O-N 3.3Å; G186-M189 CarbonylContact O-C 3.51Å; G186-M189 WeakPolarHBondContact O-CA 3.2Å; G186-M189 VanDerWaalsContact O-CB 3.31Å; G186-M189 WeakPolarHBondContact O-CB 3.46Å; G186-M189 PolarHBondContact O-N 3Å; G186-I190 PolarHBondContact O-N 3.45Å
187K74.8Confident72Confident68 Ų6857.4 Ų57.430%0.29634%0.339SS..Hα-helixtrans-51.7-54.6178.1-61179.5-68.9-165.50112.7I179 G181 M189 I190 L191I179-K187 HydrophobicContact CG2-CB 4.36Å; I179-K187 HydrophobicContact CG2-CG 4.04Å; G181-K187 WeakPolarHBondContact O-CE 3.29Å; G181-K187 PolarHBondContact O-NZ 3.37Å; K187-M189 VanDerWaalsContact C-N 3.26Å; K187-M189 PolarHBondContact O-N 3.18Å; K187-I190 WeakPolarHBondContact O-CB 3.48Å; K187-I190 PolarHBondContact O-N 2.98Å; K187-I190 VanDerWaalsContact O-N 3.14Å; K187-L191 PolarHBondContact O-N 2.85Å
188S76.2Confident71.5Confident29 Ų2954.8 Ų54.820%0.20333%0.327CS..Hα-helixtrans-63.5-32.3176-46.80000112.2G186 I190 L191 Q192 D295G186-S188 PolarHBondContact O-N 3.3Å; S188-I190 VanDerWaalsContact C-N 3.33Å; S188-I190 PolarHBondContact O-N 3.21Å; S188-L191 PolarHBondContact O-N 2.94Å; S188-Q192 WeakPolarHBondContact O-CG 3.48Å; S188-Q192 PolarHBondContact O-N 3.39Å; S188-D295 WeakPolarHBondContact CB-OD2 3.49Å; S188-D295 PolarHBondContact OG-OD1 2.96Å; S188-D295 PolarHBondContact OG-OD2 3.43Å
189M75.1Confident70.8Confident53 Ų5356.2 Ų56.226%0.26133%0.329SS..Hα-helixtrans-65.9-35.2175.6-170.1171.369.400111.9F156 G186 K187 Q192 T193 V198F156-M189 HydrophobicContact CD1-CE 3.53Å; F156-M189 HydrophobicContact CD1-CG 4.36Å; F156-M189 HydrophobicContact CD1-SD 3.65Å; F156-M189 HydrophobicContact CD2-CE 3.43Å; F156-M189 VanDerWaalsContact CD2-CE 3.43Å; F156-M189 HydrophobicContact CE1-CE 3.37Å; F156-M189 HydrophobicContact CE1-CG 3.61Å; F156-M189 HydrophobicContact CE1-SD 3.5Å; F156-M189 WeakPolarHBondContact CE1-SD 3.46Å; F156-M189 HydrophobicContact CE2-CE 3.26Å; F156-M189 HydrophobicContact CE2-SD 4.48Å; F156-M189 HydrophobicContact CG-CE 3.57Å; F156-M189 HydrophobicContact CG-SD 4.23Å; F156-M189 HydrophobicContact CZ-CE 3.23Å; F156-M189 HydrophobicContact CZ-CG 3.88Å; F156-M189 HydrophobicContact CZ-SD 3.95Å; G186-M189 CarbonylContact O-C 3.51Å; G186-M189 WeakPolarHBondContact O-CA 3.2Å; G186-M189 VanDerWaalsContact O-CB 3.31Å; G186-M189 WeakPolarHBondContact O-CB 3.46Å; G186-M189 PolarHBondContact O-N 3Å; K187-M189 VanDerWaalsContact C-N 3.26Å; K187-M189 PolarHBondContact O-N 3.18Å; M189-Q192 PolarHBondContact O-N 3.27Å; M189-T193 WeakPolarHBondContact O-CB 3.05Å; M189-T193 PolarHBondContact O-N 2.79Å; M189-T193 PolarHBondContact O-OG1 3.28Å; M189-V198 HydrophobicContact CG-CG1 4.33Å; M189-V198 HydrophobicContact CG-CG2 4.3Å
190I76.4Confident70.4Confident18 Ų1854.2 Ų54.29%0.09232%0.319CS..Hα-helixtrans-62.2-46.2172.4-64.3166.3000109.8V167 F169 I179 G186 K187 S188 T193 L194V167-I190 HydrophobicContact CG1-CD1 4.27Å; V167-I190 HydrophobicContact CG2-CD1 4.05Å; V167-I190 HydrophobicContact CG2-CG1 4.36Å; F169-I190 HydrophobicContact CE1-CG2 4.09Å; F169-I190 HydrophobicContact CZ-CG2 4.33Å; I179-I190 HydrophobicContact CD1-CG2 4.1Å; I179-I190 HydrophobicContact CG2-CD1 4.37Å; G186-I190 PolarHBondContact O-N 3.45Å; K187-I190 WeakPolarHBondContact O-CB 3.48Å; K187-I190 PolarHBondContact O-N 2.98Å; K187-I190 VanDerWaalsContact O-N 3.14Å; S188-I190 VanDerWaalsContact C-N 3.33Å; S188-I190 PolarHBondContact O-N 3.21Å; I190-T193 WeakPolarHBondContact O-CB 3.49Å; I190-T193 PolarHBondContact O-N 3.43Å; I190-T193 VanDerWaalsContact O-N 3.15Å; I190-L194 PolarHBondContact O-N 3.03Å
191L82.6Confident69.9Low16 Ų1655 Ų558%0.08432%0.32CS..Hα-helixtrans-62.7-44.4177.6-60.3-179.4000112I179 K187 S188 T193 L194 L195 L293 D295I179-L191 HydrophobicContact CD1-CD2 4.25Å; K187-L191 PolarHBondContact O-N 2.85Å; S188-L191 PolarHBondContact O-N 2.94Å; L191-T193 PolarHBondContact O-N 2.93Å; L191-L194 HydrophobicContact CD2-CD1 4.42Å; L191-L194 WeakPolarHBondContact O-CB 3.34Å; L191-L194 PolarHBondContact O-N 3.14Å; L191-L194 VanDerWaalsContact O-N 3.12Å; L191-L195 WeakPolarHBondContact O-CG 3.48Å; L191-L195 PolarHBondContact O-N 3.48Å; L191-L293 HydrophobicContact CD2-CB 4.44Å; L191-L293 HydrophobicContact CD2-CD2 4.18Å; L191-D295 HydrophobicContact CD1-CB 3.56Å
192Q80.6Confident69.7Low77 Ų7760.5 Ų60.536%0.3634%0.337SS..Hα-helixtrans-63.1-31174.6-70.4175.9-9.300112.5S188 M189 L195 K196 E197 V198S188-Q192 WeakPolarHBondContact O-CG 3.48Å; S188-Q192 PolarHBondContact O-N 3.39Å; M189-Q192 PolarHBondContact O-N 3.27Å; Q192-L195 CarbonylContact O-C 3.2Å; Q192-L195 PolarHBondContact O-N 3.02Å; Q192-K196 PolarHBondContact O-N 3.41Å; Q192-K196 VanDerWaalsContact O-N 3.1Å; Q192-E197 HydrophobicContact CB-CB 4.3Å; Q192-E197 PolarHBondContact O-N 2.89Å; Q192-V198 HydrophobicContact CB-CG2 3.7Å; Q192-V198 PolarHBondContact O-N 2.88Å
193T75.4Confident70.1Confident0 Ų057.7 Ų57.70%033%0.326CS..Hα-helixtrans-70.1-37.6173.7-52.70000111.4I154 M189 I190 L191 L195 K196 V205I154-T193 HydrophobicContact CD1-CG2 3.64Å; I154-T193 HydrophobicContact CG1-CG2 4.09Å; I154-T193 HydrophobicContact CG2-CG2 4.22Å; M189-T193 WeakPolarHBondContact O-CB 3.05Å; M189-T193 PolarHBondContact O-N 2.79Å; M189-T193 PolarHBondContact O-OG1 3.28Å; I190-T193 WeakPolarHBondContact O-CB 3.49Å; I190-T193 PolarHBondContact O-N 3.43Å; I190-T193 VanDerWaalsContact O-N 3.15Å; L191-T193 PolarHBondContact O-N 2.93Å; T193-L195 VanDerWaalsContact C-N 3.33Å; T193-K196 WeakPolarHBondContact O-CA 3.44Å; T193-K196 PolarHBondContact O-N 2.92Å; T193-V205 HydrophobicContact CG2-CG2 4.16Å
194L78.1Confident70.4Confident20 Ų2059 Ų5911%0.10533%0.329CS..Hα-helixtrans-65.4-35.9172.7-67.3174.2000112.2F152 F169 I190 L191 K196 V205 V207 L293F152-L194 HydrophobicContact CE1-CD2 4.18Å; F152-L194 HydrophobicContact CE2-CD2 4.35Å; F152-L194 HydrophobicContact CZ-CD2 3.88Å; F169-L194 HydrophobicContact CZ-CD1 4.31Å; F169-L194 HydrophobicContact CZ-CD2 4.46Å; I190-L194 PolarHBondContact O-N 3.03Å; L191-L194 HydrophobicContact CD2-CD1 4.42Å; L191-L194 WeakPolarHBondContact O-CB 3.34Å; L191-L194 PolarHBondContact O-N 3.14Å; L191-L194 VanDerWaalsContact O-N 3.12Å; L194-K196 PolarHBondContact O-N 3.32Å; L194-V205 HydrophobicContact CD2-CG1 4.27Å; L194-V207 HydrophobicContact CD2-CG2 4.09Å; L194-L293 HydrophobicContact CB-CD1 4.06Å; L194-L293 HydrophobicContact CD1-CD1 4.46Å; L194-L293 HydrophobicContact CD1-CD2 3.98Å
195L81.6Confident70.8Confident50 Ų5056.6 Ų56.626%0.26230%0.301SS..THydrogen-bonded Turntrans-72.5-9.1171.5-66.9171.3000113.3L191 Q192 T193 E197 I211 Y213 L293L191-L195 WeakPolarHBondContact O-CG 3.48Å; L191-L195 PolarHBondContact O-N 3.48Å; Q192-L195 CarbonylContact O-C 3.2Å; Q192-L195 PolarHBondContact O-N 3.02Å; T193-L195 VanDerWaalsContact C-N 3.33Å; L195-E197 HydrophobicContact CB-CG 4.17Å; L195-E197 PolarHBondContact O-N 3.24Å; L195-I211 HydrophobicContact CD2-CD1 4.44Å; L195-I211 HydrophobicContact CD2-CG2 3.93Å; L195-Y213 HydrophobicContact CD1-CD1 3.78Å; L195-Y213 HydrophobicContact CD1-CD2 3.81Å; L195-Y213 HydrophobicContact CD1-CE1 3.93Å; L195-Y213 HydrophobicContact CD1-CE2 3.96Å; L195-Y213 HydrophobicContact CD1-CG 3.71Å; L195-L293 HydrophobicContact CD2-CD1 3.94Å; L195-L293 HydrophobicContact CG-CD1 3.98Å
196K73Confident71Confident67 Ų6756.5 Ų56.529%0.29130%0.298SS..THydrogen-bonded Turntrans63.222.5-174.3-55179.9176178.80114.8Q192 T193 L194Q192-K196 PolarHBondContact O-N 3.41Å; Q192-K196 VanDerWaalsContact O-N 3.1Å; T193-K196 WeakPolarHBondContact O-CA 3.44Å; T193-K196 PolarHBondContact O-N 2.92Å; L194-K196 PolarHBondContact O-N 3.32Å
197E72.6Confident71.1Confident133 Ų13356.4 Ų56.462%0.62129%0.294SS*.  trans-76.5-29.2172.5-71.6-69155.900111.9Q192 L195Q192-E197 HydrophobicContact CB-CB 4.3Å; Q192-E197 PolarHBondContact O-N 2.89Å; L195-E197 HydrophobicContact CB-CG 4.17Å; L195-E197 PolarHBondContact O-N 3.24Å
198V67.8Low70.9Confident33 Ų3355.3 Ų55.320%0.229%0.291CS..SBendtrans-102.2120.9176.4177.30000110F156 M189 Q192 H200F156-V198 HydrophobicContact CD1-CG1 4.05Å; F156-V198 HydrophobicContact CE1-CG1 3.77Å; M189-V198 HydrophobicContact CG-CG1 4.33Å; M189-V198 HydrophobicContact CG-CG2 4.3Å; Q192-V198 HydrophobicContact CB-CG2 3.7Å; Q192-V198 PolarHBondContact O-N 2.88Å; V198-H200 PolarHBondContact O-N 3.02Å
199V64.2Low70.7Confident84 Ų8455.9 Ų55.951%0.50930%0.301SS..PPolyproline II helixtrans-72.1125.7174.7-175.10000109.1
200H63.6Low70.9Confident23 Ų2360.2 Ų60.211%0.10632%0.315CS..PPolyproline II helixtrans-103.8138.9171.855.6-81.4000109.5I154 V198 G203I154-H200 HydrophobicContact CG2-CB 3.75Å; V198-H200 PolarHBondContact O-N 3.02Å; H200-G203 PolarHBondContact NE2-O 2.74Å
201N60.1Low71.3Confident114 Ų11461.5 Ų61.561%0.6132%0.321SS*.SBendtrans-80.6-28.7-177.1-84.325.2000112.8F155 A157F155-N201 PolarHBondContact O-N 2.84Å; A157-N201 HydrophobicContact CB-CB 4.05Å; A157-N201 WeakPolarHBondContact CB-ND2 3.5Å
202K58.1Low71.5Confident140 Ų14060.7 Ų60.761%0.60932%0.317SS*.BIsolated β-bridgetrans-142.9148.3178.2-63.8179-179.9-178.60108.9T153 F155T153-K202 CarbonylContact O-C 3.53Å; F155-K202 HydrophobicContact CB-CB 3.99Å; F155-K202 HydrophobicContact CD2-CB 3.41Å; F155-K202 VanDerWaalsContact CD2-CB 3.41Å; F155-K202 HydrophobicContact CD2-CD 4.19Å; F155-K202 HydrophobicContact CD2-CG 4.4Å; F155-K202 HydrophobicContact CE2-CB 4.14Å; F155-K202 HydrophobicContact CE2-CD 4.48Å; F155-K202 HydrophobicContact CG-CB 3.99Å; F155-K202 HydrophobicContact CG-CD 4.41Å; F155-K202 PolarHBondContact N-O 2.98Å
203G62.9Low72Confident42 Ų4260.3 Ų60.343%0.43331%0.313SS..  trans119.5162.9-172.900000111.5T153 H200T153-G203 WeakPolarHBondContact O-CA 3.3Å; T153-G203 PolarHBondContact O-N 2.72Å; H200-G203 PolarHBondContact NE2-O 2.74Å
204E65.3Low72.6Confident141 Ų14160.4 Ų60.466%0.65931%0.313SS*.  trans-120136.4166.4-173.4176.4-179.500107.3F152 V206F152-E204 VanDerWaalsContact CD1-O 3.31Å; F152-E204 WeakPolarHBondContact CD1-O 3.34Å; E204-V206 HydrophobicContact CG-CG2 3.89Å
205V66.6Low73.1Confident15 Ų1561.1 Ų61.19%0.09132%0.319CS..  trans-116.5104174.9175.40000109.1F152 I154 T193 L194 V207F152-V205 HydrophobicContact CD1-CB 4.08Å; F152-V205 HydrophobicContact CD1-CG1 4.23Å; F152-V205 HydrophobicContact CD1-CG2 3.77Å; F152-V205 VanDerWaalsContact CE1-CA 3.48Å; F152-V205 HydrophobicContact CE1-CB 3.88Å; F152-V205 HydrophobicContact CE1-CG1 3.64Å; F152-V205 HydrophobicContact CE1-CG2 4.05Å; I154-V205 HydrophobicContact CG1-CG2 4.5Å; T193-V205 HydrophobicContact CG2-CG2 4.16Å; L194-V205 HydrophobicContact CD2-CG1 4.27Å; V205-V207 HydrophobicContact CG1-CG2 3.98Å
206V68.8Low73Confident44 Ų4463.5 Ų63.527%0.26733%0.329SS..  trans-102.8110.8176.6-173.40000109.2C149 E204C149-V206 PolarHBondContact SG-O 3.49Å; E204-V206 HydrophobicContact CG-CG2 3.89Å
207V70.3Confident73.3Confident18 Ų1868.5 Ų68.511%0.10935%0.353CS..  trans-123.7121.7173.2-175.80000107.5L194 V205 I211 I291L194-V207 HydrophobicContact CD2-CG2 4.09Å; V205-V207 HydrophobicContact CG1-CG2 3.98Å; V207-I211 HydrophobicContact CG1-CD1 3.71Å; V207-I211 HydrophobicContact CG1-CG1 4.16Å; V207-I291 HydrophobicContact CG1-CD1 3.43Å; V207-I291 VanDerWaalsContact CG1-CD1 3.43Å
208N69.8Low73.8Confident45 Ų4563.6 Ų63.624%0.24134%0.335CS..  trans-119.9114.9180-74.4-23.1000109.1F146F146-N208 PolarHBondContact O-ND2 3.02Å
209G73Confident74.7Confident40 Ų4068.5 Ų68.541%0.41235%0.35SS..SBendtrans136.7166.2-178.900000112D290G209-D290 WeakPolarHBondContact CA-OD2 3.5Å
210R79.3Confident75.8Confident145 Ų14564.6 Ų64.655%0.54733%0.326SS..  trans-73.1137.1168.1-66.2180-66.2165.96.9108.7D288 A289 D290 I291R210-D288 PolarHBondContact NH2-O 2.83Å; R210-A289 HydrophobicContact CB-CB 4.38Å; R210-A289 WeakPolarHBondContact O-CB 3.2Å; R210-D290 PolarHBondContact N-OD2 2.77Å; R210-D290 PolarHBondContact O-N 3.1Å; R210-I291 PolarHBondContact O-N 2.78Å
211I83.5Confident76.8Confident44 Ų4465.8 Ų65.823%0.22633%0.332CS..EExtended strand (participates in β ladder)trans-108.9131.1179.7-54.1172.7000108.8L195 V207 Q287 I291 L293L195-I211 HydrophobicContact CD2-CD1 4.44Å; L195-I211 HydrophobicContact CD2-CG2 3.93Å; V207-I211 HydrophobicContact CG1-CD1 3.71Å; V207-I211 HydrophobicContact CG1-CG1 4.16Å; I211-Q287 PolarHBondContact O-NE2 3.27Å; I211-I291 CarbonylContact C-O 3.58Å; I211-I291 WeakPolarHBondContact CA-O 3.02Å; I211-I291 HydrophobicContact CG1-CB 4.32Å; I211-I291 HydrophobicContact CG1-CD1 4.48Å; I211-L293 HydrophobicContact CG2-CD1 3.73Å; I211-L293 HydrophobicContact CG2-CG 3.81Å
212A87.5Confident77.8Confident0 Ų063.7 Ų63.70%032%0.324CS..EExtended strand (participates in β ladder)trans-103.5134.2161.700000108.3A284 Q287 A289 I291 Y292 L293A212-A284 HydrophobicContact CB-CB 4.15Å; A212-Q287 HydrophobicContact CB-CB 4.49Å; A212-A289 HydrophobicContact CB-CB 3.46Å; A212-A289 VanDerWaalsContact CB-CB 3.46Å; A212-A289 VanDerWaalsContact N-CB 3.25Å; A212-I291 PolarHBondContact N-O 3.09Å; A212-Y292 HydrophobicContact CB-CD1 3.74Å; A212-Y292 HydrophobicContact CB-CE1 3.81Å; A212-Y292 HydrophobicContact CB-CG 4.44Å; A212-Y292 WeakPolarHBondContact O-CA 3.31Å; A212-L293 PolarHBondContact O-N 3.41Å
213Y90Very high79.1Confident69 Ų6957.1 Ų57.127%0.27130%0.296SS..EExtended strand (participates in β ladder)trans-124129.1-177.4176-121.5000110.8L195 P215 L293 D295L195-Y213 HydrophobicContact CD1-CD1 3.78Å; L195-Y213 HydrophobicContact CD1-CD2 3.81Å; L195-Y213 HydrophobicContact CD1-CE1 3.93Å; L195-Y213 HydrophobicContact CD1-CE2 3.96Å; L195-Y213 HydrophobicContact CD1-CG 3.71Å; Y213-P215 HydrophobicContact CD1-CB 4.39Å; Y213-P215 HydrophobicContact CE1-CB 3.64Å; Y213-P215 HydrophobicContact CE1-CG 4.41Å; Y213-L293 WeakPolarHBondContact CA-O 3.47Å; Y213-L293 HydrophobicContact CD2-CB 3.84Å; Y213-L293 WeakPolarHBondContact CD2-O 3.37Å; Y213-D295 HydrophobicContact CE2-CB 4.08Å
214V89.7Confident80.3Confident2 Ų256.2 Ų56.21%0.01228%0.282CS..EExtended strand (participates in β ladder)trans-108.2109.4168.7-179.90000107.5N280 L281 A284 L293 L294 D295 P297V214-N280 HydrophobicContact CG1-CB 4.41Å; V214-L281 HydrophobicContact CG2-CD1 4.13Å; V214-A284 HydrophobicContact CG2-CB 3.34Å; V214-L293 PolarHBondContact N-O 3.43Å; V214-L294 HydrophobicContact CB-CD2 3.82Å; V214-L294 HydrophobicContact CG2-CD2 3.46Å; V214-L294 VanDerWaalsContact CG2-CD2 3.46Å; V214-D295 WeakPolarHBondContact O-CB 3.3Å; V214-D295 PolarHBondContact O-N 2.96Å; V214-P297 HydrophobicContact CG1-CB 4.16Å
215P86.9Confident81.5Confident34 Ų3449.6 Ų49.622%0.22125%0.251CS..  trans-72.5153.7178.329-34.1000112.1Y213 E217Y213-P215 HydrophobicContact CD1-CB 4.39Å; Y213-P215 HydrophobicContact CE1-CB 3.64Å; Y213-P215 HydrophobicContact CE1-CG 4.41Å; P215-E217 WeakPolarHBondContact CG-O 3.41Å; P215-E217 PolarHBondContact O-N 3.15Å
216Q81Confident82.7Confident101 Ų10152.5 Ų52.547%0.47226%0.261SS..SBendtrans-57.2-47.1173.9-174.3-179.510.200111.9D295 D296Q216-D295 WeakPolarHBondContact CA-O 3.38Å; Q216-D295 HydrophobicContact CB-CB 4.31Å; Q216-D295 PolarHBondContact N-O 2.99Å; Q216-D296 HydrophobicContact CG-CB 4.41Å
217E78.3Confident83.8Confident171 Ų17155.2 Ų55.280%0.79927%0.27SS*.SBendtrans-88.3112.1171.3-71.5-172.3-17900110.2P215 W219P215-E217 WeakPolarHBondContact CG-O 3.41Å; P215-E217 PolarHBondContact O-N 3.15Å; E217-W219 PolarHBondContact O-N 3.23Å
218A83.5Confident84.9Confident30 Ų3054.4 Ų54.425%0.24827%0.265CS..  trans-67.2108.5-17600000112.4K276 N280A218-K276 HydrophobicContact CB-CB 3.59Å; A218-N280 WeakPolarHBondContact CA-ND2 3.41Å
219W87.2Confident86Confident137 Ų13752.3 Ų52.352%0.51925%0.254SS..  trans-93.7122.4176.3-179.681.5000114.1E217 F221 F231 N280 R283E217-W219 PolarHBondContact O-N 3.23Å; W219-F221 HydrophobicContact CH2-CB 3.83Å; W219-F221 HydrophobicContact CH2-CD1 4.29Å; W219-F221 HydrophobicContact CH2-CG 4.5Å; W219-F221 HydrophobicContact CZ2-CB 3.92Å; W219-F221 HydrophobicContact CZ3-CD1 4.36Å; W219-F231 HydrophobicContact CH2-CE2 4.45Å; W219-F231 AromaticContact CZ3-CE2 3.84Å; W219-F231 HydrophobicContact CZ3-CE2 3.84Å; W219-F231 HydrophobicContact CZ3-CZ 4.25Å; W219-N280 PolarHBondContact N-ND2 2.88Å; W219-N280 PolarHBondContact O-ND2 2.77Å; W219-N280 PolarHBondContact O-OD1 2.83Å; W219-R283 PolarHBondContact O-NH1 2.86Å; W219-R283 PolarHBondContact O-NH2 2.92Å
220L87.2Confident87Confident1 Ų151.3 Ų51.31%0.00524%0.239CC..  trans-119.5144.2173.5-58.3179.1000109.8N228 I264 L271 K276 I279 N280L220-N228 WeakPolarHBondContact CA-OD1 3.03Å; L220-N228 HydrophobicContact CD2-CB 4.38Å; L220-I264 HydrophobicContact CD1-CD1 4.07Å; L220-I264 HydrophobicContact CD1-CG2 4.25Å; L220-L271 HydrophobicContact CD1-CD1 3.78Å; L220-K276 HydrophobicContact CD1-CB 4.24Å; L220-K276 HydrophobicContact CD1-CG 3.95Å; L220-I279 HydrophobicContact CD1-CD1 4.12Å; L220-I279 HydrophobicContact CD2-CB 4.02Å; L220-I279 HydrophobicContact CD2-CG2 3.47Å; L220-I279 VanDerWaalsContact CD2-CG2 3.47Å; L220-N280 WeakPolarHBondContact CD2-OD1 3.43Å
221F84.4Confident87.6Confident49 Ų4949.7 Ų49.722%0.21524%0.236CC..  trans-99.9156.5175.966.7-93000111.2W219 G223 Q227 N228 F231W219-F221 HydrophobicContact CH2-CB 3.83Å; W219-F221 HydrophobicContact CH2-CD1 4.29Å; W219-F221 HydrophobicContact CH2-CG 4.5Å; W219-F221 HydrophobicContact CZ2-CB 3.92Å; W219-F221 HydrophobicContact CZ3-CD1 4.36Å; F221-G223 PolarHBondContact O-N 2.98Å; F221-Q227 HydrophobicContact CE2-CB 4.22Å; F221-Q227 HydrophobicContact CZ-CB 4.09Å; F221-Q227 VanDerWaalsContact CZ-O 3.31Å; F221-Q227 WeakPolarHBondContact CZ-O 3.4Å; F221-N228 VanDerWaalsContact CD1-OD1 3.26Å; F221-N228 WeakPolarHBondContact CD1-OD1 3.16Å; F221-N228 HydrophobicContact CE1-CB 4.29Å; F221-N228 PolarHBondContact N-OD1 2.93Å; F221-N228 PolarHBondContact O-ND2 3.26Å; F221-N228 PolarHBondContact O-OD1 3.46Å; F221-F231 HydrophobicContact CD1-CD2 4.23Å; F221-F231 HydrophobicContact CD1-CE2 4.05Å; F221-F231 AromaticContact CE1-CD2 3.69Å; F221-F231 HydrophobicContact CE1-CD2 3.69Å; F221-F231 AromaticContact CE1-CE2 3.96Å; F221-F231 HydrophobicContact CE1-CE2 3.96Å
222P81.7Confident87.8Confident70 Ų7051.6 Ų51.646%0.45527%0.267SS..SBendtrans-59120.9176.5-21.631.6000111.8I264 D266P222-I264 WeakPolarHBondContact CA-O 3.5Å; P222-D266 HydrophobicContact CG-CB 4.45Å
223G83.6Confident87.9Confident2 Ų255.2 Ų55.22%0.02128%0.284CS..EExtended strand (participates in β ladder)trans158.5-173.4-174.800000111.9F221 I264F221-G223 PolarHBondContact O-N 2.98Å; G223-I264 PolarHBondContact N-O 2.94Å; G223-I264 VanDerWaalsContact N-O 3.14Å; G223-I264 WeakPolarHBondContact O-CB 3.43Å; G223-I264 PolarHBondContact O-N 3.3Å
224T88.8Confident87.8Confident22 Ų2259.3 Ų59.314%0.13531%0.311CS..EExtended strand (participates in β ladder)trans-74.9161.8176.264.90000111.9R226 Q227 N228 T262 V263T224-R226 PolarHBondContact O-N 3.21Å; T224-Q227 PolarHBondContact O-N 3.46Å; T224-Q227 VanDerWaalsContact OG1-CG 3.32Å; T224-Q227 WeakPolarHBondContact OG1-CG 3.37Å; T224-Q227 PolarHBondContact OG1-N 3.38Å; T224-N228 PolarHBondContact O-N 2.79Å; T224-N228 PolarHBondContact O-ND2 3.03Å; T224-T262 WeakPolarHBondContact CA-O 3.13Å; T224-V263 HydrophobicContact CG2-CG2 4.3Å
225I90.1Very high87.8Confident2 Ų263 Ų631%0.0133%0.328CS..Hα-helixtrans-57.8-43.1170.7-65169.4000109.9Q227 N228 V229 L249 L253 L256 D260 T262 I264 I279I225-Q227 PolarHBondContact O-N 3.41Å; I225-N228 WeakPolarHBondContact O-CB 3.48Å; I225-N228 PolarHBondContact O-N 2.96Å; I225-N228 VanDerWaalsContact O-N 3.11Å; I225-V229 HydrophobicContact CG2-CG2 4.36Å; I225-V229 WeakPolarHBondContact O-CG2 3.23Å; I225-V229 PolarHBondContact O-N 3.5Å; I225-L249 HydrophobicContact CG2-CD2 4.06Å; I225-L253 HydrophobicContact CD1-CD2 3.91Å; I225-L253 HydrophobicContact CG2-CD2 4.09Å; I225-L256 HydrophobicContact CD1-CD1 3.2Å; I225-D260 WeakPolarHBondContact CB-O 3.39Å; I225-D260 PolarHBondContact N-O 3.27Å; I225-T262 PolarHBondContact N-O 2.95Å; I225-I264 HydrophobicContact CB-CD1 4.25Å; I225-I264 HydrophobicContact CG1-CD1 3.45Å; I225-I264 VanDerWaalsContact CG1-CD1 3.45Å; I225-I264 HydrophobicContact CG1-CG1 3.81Å; I225-I279 HydrophobicContact CD1-CD1 4.49Å; I225-I279 HydrophobicContact CG1-CD1 4.22Å; I225-I279 HydrophobicContact CG2-CD1 4.19Å; I225-I279 HydrophobicContact CG2-CG1 4.12Å
226R92.2Very high87.9Confident77 Ų7765.2 Ų65.229%0.29134%0.339SS..Hα-helixtrans-54.4-51.9174.6-174.8-177-60.6177.53.9112.3T224 N228 V229 L230 Y240 D260T224-R226 PolarHBondContact O-N 3.21Å; R226-N228 VanDerWaalsContact C-N 3.26Å; R226-N228 PolarHBondContact O-N 3.43Å; R226-V229 PolarHBondContact O-N 3.25Å; R226-L230 HydrophobicContact CG-CD1 3.75Å; R226-L230 HydrophobicContact CG-CG 4.18Å; R226-L230 WeakPolarHBondContact O-CB 3.2Å; R226-L230 VanDerWaalsContact O-CG 3.3Å; R226-L230 WeakPolarHBondContact O-CG 3.49Å; R226-L230 PolarHBondContact O-N 3.48Å; R226-Y240 WeakPolarHBondContact CA-OH 3.36Å; R226-Y240 HydrophobicContact CG-CE2 4.22Å; R226-D260 HydrophobicContact CB-CB 4.48Å; R226-D260 IonicContact CZ-OD1 3.42Å; R226-D260 IonicContact CZ-OD2 3.14Å; R226-D260 VanDerWaalsContact CZ-OD2 3.28Å; R226-D260 PolarHBondContact N-O 2.9Å; R226-D260 IonicContact NE-OD2 3.53Å; R226-D260 PolarHBondContact NE-OD2 3.23Å; R226-D260 IonicContact NH2-OD1 2.96Å; R226-D260 PolarHBondContact NH2-OD1 3.22Å; R226-D260 IonicContact NH2-OD2 3.46Å; R226-D260 PolarHBondContact NH2-OD2 3.05Å
227Q92.3Very high88.2Confident101 Ų10164.7 Ų64.747%0.47234%0.342SS..Hα-helixtrans-59.3-40177.4-76.1170.1-20.800111.7F221 T224 I225 V229 F231F221-Q227 HydrophobicContact CE2-CB 4.22Å; F221-Q227 HydrophobicContact CZ-CB 4.09Å; F221-Q227 VanDerWaalsContact CZ-O 3.31Å; F221-Q227 WeakPolarHBondContact CZ-O 3.4Å; T224-Q227 PolarHBondContact O-N 3.46Å; T224-Q227 VanDerWaalsContact OG1-CG 3.32Å; T224-Q227 WeakPolarHBondContact OG1-CG 3.37Å; T224-Q227 PolarHBondContact OG1-N 3.38Å; I225-Q227 PolarHBondContact O-N 3.41Å; Q227-V229 VanDerWaalsContact C-N 3.34Å; Q227-V229 PolarHBondContact O-N 3.05Å; Q227-F231 PolarHBondContact O-N 2.81Å
228N92.7Very high88.6Confident0 Ų063.8 Ų63.80%034%0.338CS..Hα-helixtrans-63.3-37.3177.6-89.3-87.8000113.2L220 F221 T224 I225 R226 I264 I279 R283L220-N228 WeakPolarHBondContact CA-OD1 3.03Å; L220-N228 HydrophobicContact CD2-CB 4.38Å; F221-N228 VanDerWaalsContact CD1-OD1 3.26Å; F221-N228 WeakPolarHBondContact CD1-OD1 3.16Å; F221-N228 HydrophobicContact CE1-CB 4.29Å; F221-N228 PolarHBondContact N-OD1 2.93Å; F221-N228 PolarHBondContact O-ND2 3.26Å; F221-N228 PolarHBondContact O-OD1 3.46Å; T224-N228 PolarHBondContact O-N 2.79Å; T224-N228 PolarHBondContact O-ND2 3.03Å; I225-N228 WeakPolarHBondContact O-CB 3.48Å; I225-N228 PolarHBondContact O-N 2.96Å; I225-N228 VanDerWaalsContact O-N 3.11Å; R226-N228 VanDerWaalsContact C-N 3.26Å; R226-N228 PolarHBondContact O-N 3.43Å; N228-I264 HydrophobicContact CB-CD1 4.47Å; N228-I279 HydrophobicContact CB-CG2 4.05Å; N228-R283 PolarHBondContact O-NE 3.01Å; N228-R283 PolarHBondContact O-NH2 2.88Å; N228-R283 PolarHBondContact OD1-NH2 3.44Å; N228-R283 VanDerWaalsContact OD1-NH2 3.09Å
229V93Very high88.8Confident1 Ų165.7 Ų65.71%0.00634%0.338CS..Hα-helixtrans-76.1-45.8176.9173.80000111.3I225 R226 Q227 F231 Y240 I279 A282 Y286I225-V229 HydrophobicContact CG2-CG2 4.36Å; I225-V229 WeakPolarHBondContact O-CG2 3.23Å; I225-V229 PolarHBondContact O-N 3.5Å; R226-V229 PolarHBondContact O-N 3.25Å; Q227-V229 VanDerWaalsContact C-N 3.34Å; Q227-V229 PolarHBondContact O-N 3.05Å; V229-F231 VanDerWaalsContact C-N 3.32Å; V229-F231 PolarHBondContact O-N 3.44Å; V229-Y240 HydrophobicContact CB-CE2 3.86Å; V229-Y240 HydrophobicContact CG1-CD2 3.87Å; V229-Y240 HydrophobicContact CG1-CE2 3.65Å; V229-I279 HydrophobicContact CG2-CG2 4.08Å; V229-A282 HydrophobicContact CG1-CB 4.08Å; V229-A282 HydrophobicContact CG2-CB 3.92Å; V229-Y286 HydrophobicContact CG1-CG 4.36Å
230L93.5Very high88.9Confident20 Ų2059.7 Ų59.711%0.10532%0.316CS..Hα-helixtrans-66.3-32.6-179.6-65.9179.1000112.9R226 G232 Q233 M235 Y240 Y286R226-L230 HydrophobicContact CG-CD1 3.75Å; R226-L230 HydrophobicContact CG-CG 4.18Å; R226-L230 WeakPolarHBondContact O-CB 3.2Å; R226-L230 VanDerWaalsContact O-CG 3.3Å; R226-L230 WeakPolarHBondContact O-CG 3.49Å; R226-L230 PolarHBondContact O-N 3.48Å; L230-G232 VanDerWaalsContact C-N 3.26Å; L230-G232 PolarHBondContact O-N 3.45Å; L230-Q233 WeakPolarHBondContact O-CB 3.32Å; L230-Q233 PolarHBondContact O-N 3.01Å; L230-M235 HydrophobicContact CD1-CB 3.92Å; L230-M235 HydrophobicContact CD1-CG 4.32Å; L230-M235 HydrophobicContact CD2-CB 4.09Å; L230-M235 HydrophobicContact CD2-CG 4.13Å; L230-Y240 HydrophobicContact CD2-CD2 3.86Å; L230-Y240 HydrophobicContact CD2-CE2 4.32Å; L230-Y240 HydrophobicContact CG-CD2 4.48Å; L230-Y240 HydrophobicContact CG-CE2 4.46Å; L230-Y286 HydrophobicContact CD2-CD1 4.09Å; L230-Y286 HydrophobicContact CD2-CE1 3.36Å; L230-Y286 HydrophobicContact CD2-CE2 4.07Å; L230-Y286 WeakPolarHBondContact CD2-OH 3.48Å
231F92.2Very high89Confident110 Ų11067.4 Ų67.448%0.48235%0.345SS..THydrogen-bonded Turntrans50.542.1177-155.5-105.6000114.2W219 F221 Q227 V229 R283W219-F231 HydrophobicContact CH2-CE2 4.45Å; W219-F231 AromaticContact CZ3-CE2 3.84Å; W219-F231 HydrophobicContact CZ3-CE2 3.84Å; W219-F231 HydrophobicContact CZ3-CZ 4.25Å; F221-F231 HydrophobicContact CD1-CD2 4.23Å; F221-F231 HydrophobicContact CD1-CE2 4.05Å; F221-F231 AromaticContact CE1-CD2 3.69Å; F221-F231 HydrophobicContact CE1-CD2 3.69Å; F221-F231 AromaticContact CE1-CE2 3.96Å; F221-F231 HydrophobicContact CE1-CE2 3.96Å; Q227-F231 PolarHBondContact O-N 2.81Å; V229-F231 VanDerWaalsContact C-N 3.32Å; V229-F231 PolarHBondContact O-N 3.44Å; F231-R283 HydrophobicContact CB-CG 3.97Å; F231-R283 HydrophobicContact CD2-CG 4.46Å; F231-R283 HydrophobicContact CG-CG 4.3Å
232G88.1Confident89.1Confident84 Ų8468.7 Ų68.787%0.86635%0.354SS*.THydrogen-bonded Turntrans82.83.6179.700000115.5L230L230-G232 VanDerWaalsContact C-N 3.26Å; L230-G232 PolarHBondContact O-N 3.45Å
233Q89Confident89.5Confident77 Ų7765.4 Ų65.436%0.3633%0.332SS..SBendtrans-84.1154.6168.8-59.6-175-0.400111.2L230 Y286L230-Q233 WeakPolarHBondContact O-CB 3.32Å; L230-Q233 PolarHBondContact O-N 3.01Å; Q233-Y286 HydrophobicContact CB-CE1 4.07Å
234D89.3Confident89.8Confident155 Ų15565.7 Ų65.783%0.82933%0.333SS*.  trans-67.9145.1173.1-64.7-44.8000110.8D236 Y286D234-D236 PolarHBondContact O-N 2.98Å; D234-D236 VanDerWaalsContact O-N 3.13Å; D234-Y286 PolarHBondContact O-OH 3.35Å
235M88.8Confident89.7Confident78 Ų7870.8 Ų70.838%0.38436%0.356SS..  trans-78.298.7-175.6-172.9175.8-173.900112.1L230 Y240 Y286L230-M235 HydrophobicContact CD1-CB 3.92Å; L230-M235 HydrophobicContact CD1-CG 4.32Å; L230-M235 HydrophobicContact CD2-CB 4.09Å; L230-M235 HydrophobicContact CD2-CG 4.13Å; M235-Y240 HydrophobicContact CE-CD1 3.45Å; M235-Y240 VanDerWaalsContact CE-CD1 3.45Å; M235-Y240 HydrophobicContact CE-CE1 3.72Å; M235-Y240 HydrophobicContact CE-CG 3.89Å; M235-Y286 WeakPolarHBondContact CA-OH 3.27Å
236D88.9Confident89.5Confident82 Ų8272 Ų7244%0.43936%0.363SS..  trans-76.7116.1155.9-175.2-30.6000110.1D234 E238 R239 Y240 Y286D234-D236 PolarHBondContact O-N 2.98Å; D234-D236 VanDerWaalsContact O-N 3.13Å; D236-E238 PolarHBondContact OD1-N 2.86Å; D236-R239 HydrophobicContact CB-CB 3.96Å; D236-R239 PolarHBondContact OD1-N 3.14Å; D236-Y240 WeakPolarHBondContact O-CB 3.3Å; D236-Y240 PolarHBondContact O-N 3.33Å; D236-Y286 PolarHBondContact N-OH 2.95Å
237V88Confident89.3Confident89 Ų8968.3 Ų68.354%0.53935%0.349SS..Hα-helixtrans-65.5-41.4-174.11800000112.2R241V237-R241 WeakPolarHBondContact O-CB 3.37Å; V237-R241 PolarHBondContact O-N 3.01Å
238E87.2Confident89Confident153 Ų15364.5 Ų64.572%0.71534%0.335SS*.Hα-helixtrans-69.6-50.8-177.6-66.5-170.1164.300109.6D236 Y240 R241 D242D236-E238 PolarHBondContact OD1-N 2.86Å; E238-Y240 VanDerWaalsContact C-N 3.27Å; E238-Y240 PolarHBondContact O-N 3.49Å; E238-R241 WeakPolarHBondContact O-CB 3.4Å; E238-R241 PolarHBondContact O-N 2.92Å; E238-R241 VanDerWaalsContact O-N 3.16Å; E238-D242 PolarHBondContact O-N 3.46Å
239R86.3Confident88.7Confident69 Ų6964.6 Ų64.626%0.2634%0.335SS..Hα-helixtrans-62.2-35178.6-176172.1163153.9-17.7112.8D236 A243 Y286 Q287 D288D236-R239 HydrophobicContact CB-CB 3.96Å; D236-R239 PolarHBondContact OD1-N 3.14Å; R239-A243 WeakPolarHBondContact O-CB 3.42Å; R239-A243 PolarHBondContact O-N 3.32Å; R239-Y286 HydrophobicContact CB-CD2 4.45Å; R239-Y286 HydrophobicContact CB-CE2 4.02Å; R239-Y286 HydrophobicContact CG-CD2 3.85Å; R239-Y286 HydrophobicContact CG-CE2 3.8Å; R239-Y286 PolarHBondContact NE-O 3.35Å; R239-Y286 PolarHBondContact NH2-O 2.95Å; R239-Q287 PolarHBondContact NH2-O 3.03Å; R239-D288 IonicContact CZ-OD2 3.42Å; R239-D288 IonicContact NH1-OD2 3.23Å; R239-D288 PolarHBondContact NH1-OD2 2.94Å
240Y90.8Very high88.2Confident11 Ų1168.8 Ų68.84%0.04336%0.356CS..Hα-helixtrans-68.3-45.5177.1-179.1-103.1000110.5R226 V229 L230 M235 D236 E238 D242 A243 L244 D260 Y286R226-Y240 WeakPolarHBondContact CA-OH 3.36Å; R226-Y240 HydrophobicContact CG-CE2 4.22Å; V229-Y240 HydrophobicContact CB-CE2 3.86Å; V229-Y240 HydrophobicContact CG1-CD2 3.87Å; V229-Y240 HydrophobicContact CG1-CE2 3.65Å; L230-Y240 HydrophobicContact CD2-CD2 3.86Å; L230-Y240 HydrophobicContact CD2-CE2 4.32Å; L230-Y240 HydrophobicContact CG-CD2 4.48Å; L230-Y240 HydrophobicContact CG-CE2 4.46Å; M235-Y240 HydrophobicContact CE-CD1 3.45Å; M235-Y240 VanDerWaalsContact CE-CD1 3.45Å; M235-Y240 HydrophobicContact CE-CE1 3.72Å; M235-Y240 HydrophobicContact CE-CG 3.89Å; D236-Y240 WeakPolarHBondContact O-CB 3.3Å; D236-Y240 PolarHBondContact O-N 3.33Å; E238-Y240 VanDerWaalsContact C-N 3.27Å; E238-Y240 PolarHBondContact O-N 3.49Å; Y240-D242 VanDerWaalsContact C-N 3.31Å; Y240-D242 PolarHBondContact O-N 3.04Å; Y240-A243 PolarHBondContact O-N 2.72Å; Y240-L244 HydrophobicContact CD1-CD1 3.79Å; Y240-L244 HydrophobicContact CD1-CG 4.31Å; Y240-L244 HydrophobicContact CE1-CD1 3.38Å; Y240-L244 HydrophobicContact CE1-CG 4.11Å; Y240-L244 VanDerWaalsContact O-CG 3.3Å; Y240-L244 WeakPolarHBondContact O-CG 3.17Å; Y240-L244 PolarHBondContact O-N 3.44Å; Y240-D260 WeakPolarHBondContact OH-CB 3.13Å; Y240-D260 PolarHBondContact OH-OD2 3.26Å; Y240-Y286 HydrophobicContact CD2-CD2 4.38Å; Y240-Y286 HydrophobicContact CD2-CE2 4.3Å
241R88.8Confident87.6Confident164 Ų16476.9 Ų76.962%0.61939%0.385SS*.Hα-helixtrans-59.9-42.7175.2-177.7-178.9-76.3167.9-4.6111.3V237 E238 L244 H245V237-R241 WeakPolarHBondContact O-CB 3.37Å; V237-R241 PolarHBondContact O-N 3.01Å; E238-R241 WeakPolarHBondContact O-CB 3.4Å; E238-R241 PolarHBondContact O-N 2.92Å; E238-R241 VanDerWaalsContact O-N 3.16Å; R241-L244 PolarHBondContact O-N 3.13Å; R241-H245 WeakPolarHBondContact O-CB 3.37Å; R241-H245 PolarHBondContact O-N 2.92Å
242D86.8Confident87.1Confident76 Ų7672.3 Ų72.341%0.40637%0.366SS..Hα-helixtrans-63.8-45177-70.8-13.3000111.4E238 Y240 L244 H245 V246E238-D242 PolarHBondContact O-N 3.46Å; Y240-D242 VanDerWaalsContact C-N 3.31Å; Y240-D242 PolarHBondContact O-N 3.04Å; D242-L244 VanDerWaalsContact C-N 3.31Å; D242-L244 PolarHBondContact O-N 3.34Å; D242-H245 PolarHBondContact O-N 2.95Å; D242-H245 VanDerWaalsContact O-N 3.1Å; D242-V246 WeakPolarHBondContact O-CG2 3.46Å; D242-V246 PolarHBondContact O-N 2.84Å
243A89.9Confident86.9Confident0 Ų069 Ų690%033%0.328CS..Hα-helixtrans-60-40.1175.600000112.3R239 Y240 S247 V285 Y286R239-A243 WeakPolarHBondContact O-CB 3.42Å; R239-A243 PolarHBondContact O-N 3.32Å; Y240-A243 PolarHBondContact O-N 2.72Å; A243-S247 VanDerWaalsContact O-CB 3.27Å; A243-S247 WeakPolarHBondContact O-CB 3.46Å; A243-S247 PolarHBondContact O-N 3.03Å; A243-S247 VanDerWaalsContact O-N 3.09Å; A243-S247 PolarHBondContact O-OG 2.75Å; A243-V285 HydrophobicContact CB-CB 4.28Å; A243-V285 HydrophobicContact CB-CG1 4.01Å; A243-Y286 HydrophobicContact CB-CD2 4.21Å
244L89.9Confident86.5Confident8 Ų871.3 Ų71.34%0.04235%0.347CS..Hα-helixtrans-67.6-33.9174.7-68.6-177.5000113Y240 R241 D242 S247 A248 L249 M250 L253Y240-L244 HydrophobicContact CD1-CD1 3.79Å; Y240-L244 HydrophobicContact CD1-CG 4.31Å; Y240-L244 HydrophobicContact CE1-CD1 3.38Å; Y240-L244 HydrophobicContact CE1-CG 4.11Å; Y240-L244 VanDerWaalsContact O-CG 3.3Å; Y240-L244 WeakPolarHBondContact O-CG 3.17Å; Y240-L244 PolarHBondContact O-N 3.44Å; R241-L244 PolarHBondContact O-N 3.13Å; D242-L244 VanDerWaalsContact C-N 3.31Å; D242-L244 PolarHBondContact O-N 3.34Å; L244-S247 PolarHBondContact O-OG 3.35Å; L244-A248 PolarHBondContact O-N 3.42Å; L244-L249 HydrophobicContact CD2-CB 4.1Å; L244-L249 HydrophobicContact CD2-CD2 3.63Å; L244-L249 HydrophobicContact CD2-CG 4.35Å; L244-L249 PolarHBondContact O-N 2.98Å; L244-M250 HydrophobicContact CB-CG 4.14Å; L244-M250 HydrophobicContact CB-SD 4Å; L244-M250 HydrophobicContact CD1-SD 4.02Å; L244-L253 HydrophobicContact CD1-CD1 3.71Å; L244-L253 HydrophobicContact CD2-CD1 3.91Å; L244-L253 HydrophobicContact CG-CD1 4.41Å
245H87.1Confident85.7Confident129 Ų12972.1 Ų72.160%0.59734%0.339SS*.Hα-helixtrans-71.9-51.7177.9-170.671.7000111.3R241 D242 S247 A248R241-H245 WeakPolarHBondContact O-CB 3.37Å; R241-H245 PolarHBondContact O-N 2.92Å; D242-H245 PolarHBondContact O-N 2.95Å; D242-H245 VanDerWaalsContact O-N 3.1Å; H245-S247 VanDerWaalsContact C-N 3.29Å; H245-S247 PolarHBondContact O-N 2.84Å; H245-A248 WeakPolarHBondContact O-CA 3.4Å; H245-A248 PolarHBondContact O-N 3.32Å
246V85.9Confident85Confident27 Ų2770.1 Ų70.116%0.16433%0.329CS..Hα-helixtrans-60.5-38.9179.3172.80000111.5D242 A248 V285 F313D242-V246 WeakPolarHBondContact O-CG2 3.46Å; D242-V246 PolarHBondContact O-N 2.84Å; V246-A248 PolarHBondContact O-N 3.16Å; V246-V285 HydrophobicContact CG1-CG2 4.23Å; V246-F313 HydrophobicContact CG1-CD1 4.41Å; V246-F313 HydrophobicContact CG1-CE1 3.95Å; V246-F313 HydrophobicContact CG1-CE2 4.28Å; V246-F313 HydrophobicContact CG1-CZ 3.87Å
247S86.6Confident84Confident0 Ų072.2 Ų72.20%035%0.347CS..THydrogen-bonded Turntrans-79.2-1176.661.50000114A243 L244 H245 L249 R278 A282A243-S247 VanDerWaalsContact O-CB 3.27Å; A243-S247 WeakPolarHBondContact O-CB 3.46Å; A243-S247 PolarHBondContact O-N 3.03Å; A243-S247 VanDerWaalsContact O-N 3.09Å; A243-S247 PolarHBondContact O-OG 2.75Å; L244-S247 PolarHBondContact O-OG 3.35Å; H245-S247 VanDerWaalsContact C-N 3.29Å; H245-S247 PolarHBondContact O-N 2.84Å; S247-L249 PolarHBondContact O-N 3.14Å; S247-L249 VanDerWaalsContact O-N 3.16Å; S247-R278 WeakPolarHBondContact CB-O 3.48Å; S247-R278 WeakPolarHBondContact O-CD 3.38Å; S247-R278 VanDerWaalsContact O-CG 3.23Å; S247-R278 WeakPolarHBondContact O-CG 3.45Å; S247-A282 WeakPolarHBondContact OG-CB 3.45Å
248A86Confident83.4Confident21 Ų2171.2 Ų71.217%0.17434%0.336CS..THydrogen-bonded Turntrans54.825.1-174.700000114.8L244 H245 V246 V305 I309L244-A248 PolarHBondContact O-N 3.42Å; H245-A248 WeakPolarHBondContact O-CA 3.4Å; H245-A248 PolarHBondContact O-N 3.32Å; V246-A248 PolarHBondContact O-N 3.16Å; A248-V305 HydrophobicContact CB-CG1 3.73Å; A248-I309 HydrophobicContact CB-CD1 4.44Å; A248-I309 HydrophobicContact CB-CG1 4.07Å
249L86.9Confident83.2Confident2 Ų264.9 Ų64.91%0.0131%0.311CS..THydrogen-bonded Turntrans-78-19.7-175.1-16370.9000113I225 L244 S247 R251 D252 L253 R278 I279I225-L249 HydrophobicContact CG2-CD2 4.06Å; L244-L249 HydrophobicContact CD2-CB 4.1Å; L244-L249 HydrophobicContact CD2-CD2 3.63Å; L244-L249 HydrophobicContact CD2-CG 4.35Å; L244-L249 PolarHBondContact O-N 2.98Å; S247-L249 PolarHBondContact O-N 3.14Å; S247-L249 VanDerWaalsContact O-N 3.16Å; L249-R251 PolarHBondContact O-N 3.17Å; L249-R251 VanDerWaalsContact O-N 3.14Å; L249-D252 HydrophobicContact CD1-CB 4.23Å; L249-D252 WeakPolarHBondContact O-CB 3.48Å; L249-D252 PolarHBondContact O-N 2.97Å; L249-L253 HydrophobicContact CD2-CD2 4.39Å; L249-L253 HydrophobicContact CD2-CG 4.48Å; L249-L253 HydrophobicContact CG-CG 4.25Å; L249-L253 PolarHBondContact O-N 3.31Å; L249-L253 VanDerWaalsContact O-N 3.08Å; L249-R278 HydrophobicContact CD1-CB 3.72Å; L249-I279 HydrophobicContact CD1-CG1 3.78Å; L249-I279 HydrophobicContact CD2-CG1 3.7Å; L249-I279 HydrophobicContact CG-CG1 4.43Å
250M83.1Confident83.2Confident90 Ų9062.9 Ų62.944%0.44331%0.306SS..Hα-helixtrans-52.3-39.5-178.5-73.4-65.1-73.900113.5L244 D252 L253 V254L244-M250 HydrophobicContact CB-CG 4.14Å; L244-M250 HydrophobicContact CB-SD 4Å; L244-M250 HydrophobicContact CD1-SD 4.02Å; M250-D252 VanDerWaalsContact C-N 3.31Å; M250-D252 PolarHBondContact O-N 2.96Å; M250-L253 PolarHBondContact O-N 3.44Å; M250-V254 WeakPolarHBondContact O-CG2 3.47Å; M250-V254 PolarHBondContact O-N 2.88Å
251R80.3Confident82.9Confident189 Ų18966 Ų6671%0.71332%0.323SS*.Hα-helixtrans-67.5-31.9179-65.4-179-178.7175.70.9112.8L249L249-R251 PolarHBondContact O-N 3.17Å; L249-R251 VanDerWaalsContact O-N 3.14Å
252D82.2Confident82.5Confident14 Ų1459.2 Ų59.28%0.07530%0.3CS..Hα-helixtrans-73.9-43.3176.6-66.4-64.9000111.1L249 M250 V254 R255 L256 Q275 R278L249-D252 HydrophobicContact CD1-CB 4.23Å; L249-D252 WeakPolarHBondContact O-CB 3.48Å; L249-D252 PolarHBondContact O-N 2.97Å; M250-D252 VanDerWaalsContact C-N 3.31Å; M250-D252 PolarHBondContact O-N 2.96Å; D252-V254 VanDerWaalsContact C-N 3.31Å; D252-V254 PolarHBondContact O-N 3.13Å; D252-R255 WeakPolarHBondContact O-CB 3.43Å; D252-R255 PolarHBondContact O-N 2.84Å; D252-L256 PolarHBondContact O-N 3.05Å; D252-Q275 HydrophobicContact CB-CG 4.39Å; D252-Q275 WeakPolarHBondContact OD1-CG 3.12Å; D252-Q275 PolarHBondContact OD1-NE2 3.43Å; D252-R278 VanDerWaalsContact CG-NH2 3.25Å; D252-R278 IonicContact OD1-NH2 3.16Å; D252-R278 PolarHBondContact OD1-NH2 2.8Å; D252-R278 IonicContact OD2-CZ 3.36Å; D252-R278 IonicContact OD2-NE 3.47Å; D252-R278 PolarHBondContact OD2-NE 2.82Å; D252-R278 IonicContact OD2-NH2 2.74Å; D252-R278 PolarHBondContact OD2-NH2 3.37Å
253L83.4Confident82Confident16 Ų1657.9 Ų57.98%0.08429%0.294CS..Hα-helixtrans-59.1-42.2-178.5-66.1179.5000111.8I225 L244 L249 M250 R255 L256 G259 D260I225-L253 HydrophobicContact CD1-CD2 3.91Å; I225-L253 HydrophobicContact CG2-CD2 4.09Å; L244-L253 HydrophobicContact CD1-CD1 3.71Å; L244-L253 HydrophobicContact CD2-CD1 3.91Å; L244-L253 HydrophobicContact CG-CD1 4.41Å; L249-L253 HydrophobicContact CD2-CD2 4.39Å; L249-L253 HydrophobicContact CD2-CG 4.48Å; L249-L253 HydrophobicContact CG-CG 4.25Å; L249-L253 PolarHBondContact O-N 3.31Å; L249-L253 VanDerWaalsContact O-N 3.08Å; M250-L253 PolarHBondContact O-N 3.44Å; L253-R255 PolarHBondContact O-N 2.94Å; L253-R255 VanDerWaalsContact O-N 3.14Å; L253-L256 HydrophobicContact CD2-CD1 4.34Å; L253-L256 PolarHBondContact O-N 3.03Å; L253-L256 VanDerWaalsContact O-N 3.07Å; L253-G259 WeakPolarHBondContact O-CA 3.45Å; L253-D260 HydrophobicContact CD1-CB 4.13Å; L253-D260 HydrophobicContact CD2-CB 3.97Å
254V80.6Confident81.4Confident125 Ų12558 Ų5876%0.75830%0.295SS*.THydrogen-bonded Turntrans-59-27.5177.5174.20000112.8M250 D252M250-V254 WeakPolarHBondContact O-CG2 3.47Å; M250-V254 PolarHBondContact O-N 2.88Å; D252-V254 VanDerWaalsContact C-N 3.31Å; D252-V254 PolarHBondContact O-N 3.13Å
255R73.3Confident80.3Confident172 Ų17259.2 Ų59.265%0.64931%0.309SS*.THydrogen-bonded Turntrans-86-17.6-179.8-66.9176.1171.2-174.1-7113.4D252 L253D252-R255 WeakPolarHBondContact O-CB 3.43Å; D252-R255 PolarHBondContact O-N 2.84Å; L253-R255 PolarHBondContact O-N 2.94Å; L253-R255 VanDerWaalsContact O-N 3.14Å
256L73.1Confident79.2Confident35 Ų3557.5 Ų57.518%0.18330%0.304CS..SBendtrans-82.3139-179.5-66.1173.5000109.9I225 D252 L253 K258 G259 T262I225-L256 HydrophobicContact CD1-CD1 3.2Å; D252-L256 PolarHBondContact O-N 3.05Å; L253-L256 HydrophobicContact CD2-CD1 4.34Å; L253-L256 PolarHBondContact O-N 3.03Å; L253-L256 VanDerWaalsContact O-N 3.07Å; L256-K258 PolarHBondContact O-N 3Å; L256-G259 PolarHBondContact O-N 3.33Å; L256-T262 WeakPolarHBondContact CB-OG1 3.4Å; L256-T262 HydrophobicContact CD1-CG2 4.43Å; L256-T262 HydrophobicContact CD2-CG2 4.46Å
257P67.5Low78.1Confident126 Ų12662.3 Ų62.382%0.81832%0.323SS*.THydrogen-bonded Turntrans-60.4-21.9-172.623.1-33.6000113.9
258K75.5Confident77Confident69 Ų6962.3 Ų62.330%0.332%0.323SS..THydrogen-bonded Turntrans-124.519.8177.6-63.7-166.9169.2-155.70113.2L256 D260 L261 F363L256-K258 PolarHBondContact O-N 3Å; K258-D260 PolarHBondContact O-N 2.91Å; K258-L261 HydrophobicContact CB-CB 4.38Å; K258-L261 WeakPolarHBondContact O-CB 3.47Å; K258-L261 PolarHBondContact O-N 3.41Å; K258-F363 VanDerWaalsContact NZ-CG 3.33Å
259G83.1Confident75.9Confident19 Ų1964.8 Ų64.820%0.19634%0.336CS..G310 helixtrans55.8-129.2-177.300000112L253 L256 L261 T262L253-G259 WeakPolarHBondContact O-CA 3.45Å; L256-G259 PolarHBondContact O-N 3.33Å; G259-L261 VanDerWaalsContact C-N 3.32Å; G259-T262 WeakPolarHBondContact O-CB 3.48Å; G259-T262 PolarHBondContact O-N 3.46Å; G259-T262 PolarHBondContact O-OG1 3.41Å
260D85.5Confident75Confident28 Ų2869.7 Ų69.715%0.1537%0.366CS..G310 helixtrans-78.7-13.6-17970.8-27.5000114.3I225 R226 Y240 L253 K258 T262I225-D260 WeakPolarHBondContact CB-O 3.39Å; I225-D260 PolarHBondContact N-O 3.27Å; R226-D260 HydrophobicContact CB-CB 4.48Å; R226-D260 IonicContact CZ-OD1 3.42Å; R226-D260 IonicContact CZ-OD2 3.14Å; R226-D260 VanDerWaalsContact CZ-OD2 3.28Å; R226-D260 PolarHBondContact N-O 2.9Å; R226-D260 IonicContact NE-OD2 3.53Å; R226-D260 PolarHBondContact NE-OD2 3.23Å; R226-D260 IonicContact NH2-OD1 2.96Å; R226-D260 PolarHBondContact NH2-OD1 3.22Å; R226-D260 IonicContact NH2-OD2 3.46Å; R226-D260 PolarHBondContact NH2-OD2 3.05Å; Y240-D260 WeakPolarHBondContact OH-CB 3.13Å; Y240-D260 PolarHBondContact OH-OD2 3.26Å; L253-D260 HydrophobicContact CD1-CB 4.13Å; L253-D260 HydrophobicContact CD2-CB 3.97Å; K258-D260 PolarHBondContact O-N 2.91Å; D260-T262 PolarHBondContact O-N 3.35Å
261L85Confident74.4Confident77 Ų7766.1 Ų66.140%0.40335%0.349SS..G310 helixtrans-81.92.7172.3-62178.2000112.7K258 G259 V263K258-L261 HydrophobicContact CB-CB 4.38Å; K258-L261 WeakPolarHBondContact O-CB 3.47Å; K258-L261 PolarHBondContact O-N 3.41Å; G259-L261 VanDerWaalsContact C-N 3.32Å; L261-V263 PolarHBondContact O-N 3.31Å
262T80.8Confident74.1Confident21 Ų2158.4 Ų58.413%0.12932%0.324CS..PPolyproline II helixtrans-61.9123.4174.4-570000109.9T224 I225 L256 G259 D260T224-T262 WeakPolarHBondContact CA-O 3.13Å; I225-T262 PolarHBondContact N-O 2.95Å; L256-T262 WeakPolarHBondContact CB-OG1 3.4Å; L256-T262 HydrophobicContact CD1-CG2 4.43Å; L256-T262 HydrophobicContact CD2-CG2 4.46Å; G259-T262 WeakPolarHBondContact O-CB 3.48Å; G259-T262 PolarHBondContact O-N 3.46Å; G259-T262 PolarHBondContact O-OG1 3.41Å; D260-T262 PolarHBondContact O-N 3.35Å
263V76.1Confident73.6Confident48 Ų4859.9 Ų59.929%0.29134%0.342SS..EExtended strand (participates in β ladder)trans-77.8124.9-179.9-179.10000109.7T224 L261 F363 I365T224-V263 HydrophobicContact CG2-CG2 4.3Å; L261-V263 PolarHBondContact O-N 3.31Å; V263-F363 HydrophobicContact CG2-CB 4.4Å; V263-I365 HydrophobicContact CG1-CG1 3.82Å
264I77.6Confident73.4Confident2 Ų259.2 Ų59.21%0.0134%0.34CS..EExtended strand (participates in β ladder)trans-95.6126.3175.9-54.5167.9000107.8L220 P222 G223 I225 N228 L271 I279L220-I264 HydrophobicContact CD1-CD1 4.07Å; L220-I264 HydrophobicContact CD1-CG2 4.25Å; P222-I264 WeakPolarHBondContact CA-O 3.5Å; G223-I264 PolarHBondContact N-O 2.94Å; G223-I264 VanDerWaalsContact N-O 3.14Å; G223-I264 WeakPolarHBondContact O-CB 3.43Å; G223-I264 PolarHBondContact O-N 3.3Å; I225-I264 HydrophobicContact CB-CD1 4.25Å; I225-I264 HydrophobicContact CG1-CD1 3.45Å; I225-I264 VanDerWaalsContact CG1-CD1 3.45Å; I225-I264 HydrophobicContact CG1-CG1 3.81Å; N228-I264 HydrophobicContact CB-CD1 4.47Å; I264-L271 HydrophobicContact CD1-CD1 3.84Å; I264-L271 HydrophobicContact CG1-CD1 3.93Å; I264-L271 HydrophobicContact CG2-CD1 4.18Å; I264-I279 HydrophobicContact CD1-CD1 4.34Å
265G67.4Low73.6Confident33 Ų3355 Ų5534%0.3431%0.311SS..  trans-73.5-175.1173.600000113K267 G268G265-K267 PolarHBondContact O-N 2.91Å; G265-G268 PolarHBondContact O-N 2.92Å
266D62.4Low74.3Confident94 Ų9448.7 Ų48.750%0.50329%0.289SS..G310 helixtrans-56.4127.9178.6-160.83.1000111.4P222 G268P222-D266 HydrophobicContact CG-CB 4.45Å; D266-G268 PolarHBondContact O-N 3.01Å
267K63.8Low74.9Confident127 Ų12747.6 Ų47.655%0.55229%0.285SS*.G310 helixtrans55.810.7-172.9-53.2-178.7-179.9-1800116.2G265 T269 K276G265-K267 PolarHBondContact O-N 2.91Å; K267-T269 PolarHBondContact O-N 3.49Å; K267-K276 PolarHBondContact O-NZ 3.25Å
268G62.5Low76Confident0 Ų042.8 Ų42.80%025%0.25CS..G310 helixtrans56.642.5179.600000115.7G265 D266 T270 L271 K276G265-G268 PolarHBondContact O-N 2.92Å; D266-G268 PolarHBondContact O-N 3.01Å; G268-T270 PolarHBondContact O-N 3.11Å; G268-L271 PolarHBondContact O-N 3.44Å; G268-K276 WeakPolarHBondContact O-CE 3.4Å; G268-K276 PolarHBondContact O-NZ 2.81Å
269T63.7Low76.8Confident74 Ų7439.6 Ų39.645%0.45424%0.236SC..THydrogen-bonded Turntrans-52.5-22.7178.752.30000114.7K267 L271K267-T269 PolarHBondContact O-N 3.49Å; T269-L271 VanDerWaalsContact C-N 3.32Å
270T67.4Low77.2Confident104 Ų10438.9 Ų38.964%0.63823%0.228SC*.THydrogen-bonded Turntrans-75.6-16176.752.80000114.2G268G268-T270 PolarHBondContact O-N 3.11Å
271L71.9Confident77.4Confident16 Ų1637.7 Ų37.78%0.08422%0.222CC..SBendtrans-102.4147.2-177.6-62.8175.8000111.7L220 I264 G268 T269 Q275 K276 I279L220-L271 HydrophobicContact CD1-CD1 3.78Å; I264-L271 HydrophobicContact CD1-CD1 3.84Å; I264-L271 HydrophobicContact CG1-CD1 3.93Å; I264-L271 HydrophobicContact CG2-CD1 4.18Å; G268-L271 PolarHBondContact O-N 3.44Å; T269-L271 VanDerWaalsContact C-N 3.32Å; L271-Q275 HydrophobicContact CB-CB 4.29Å; L271-K276 HydrophobicContact CB-CG 4.01Å; L271-K276 WeakPolarHBondContact O-CE 3.32Å; L271-I279 HydrophobicContact CD1-CD1 3.47Å; L271-I279 VanDerWaalsContact CD1-CD1 3.47Å
272S73.6Confident77.8Confident27 Ų2734 Ų3419%0.18920%0.203CC..  trans-70.7156172.865.60000112.3G274 Q275 K276S272-G274 VanDerWaalsContact C-N 3.29Å; S272-G274 PolarHBondContact O-N 3.48Å; S272-Q275 WeakPolarHBondContact O-CB 3.4Å; S272-Q275 PolarHBondContact O-N 3.14Å; S272-Q275 VanDerWaalsContact OG-CD 3.24Å; S272-Q275 VanDerWaalsContact OG-CG 3.24Å; S272-Q275 WeakPolarHBondContact OG-CG 3.47Å; S272-Q275 PolarHBondContact OG-N 3.02Å; S272-Q275 PolarHBondContact OG-OE1 3.15Å; S272-K276 WeakPolarHBondContact O-CG 3.36Å; S272-K276 PolarHBondContact O-N 3.31Å
273G71.2Confident78.3Confident44 Ų4434.4 Ų34.445%0.45420%0.202SC..Hα-helixtrans-52.5-44.5178.100000113.2Q275 K276 A277G273-Q275 PolarHBondContact O-N 3.13Å; G273-K276 PolarHBondContact O-N 2.95Å; G273-A277 WeakPolarHBondContact O-CB 3.4Å; G273-A277 PolarHBondContact O-N 2.99Å
274G79.2Confident79Confident3 Ų332.3 Ų32.33%0.03119%0.189CC..Hα-helixtrans-64.2-36176.600000113.9S272 A277 R278 A300S272-G274 VanDerWaalsContact C-N 3.29Å; S272-G274 PolarHBondContact O-N 3.48Å; G274-A277 PolarHBondContact O-N 3.32Å; G274-R278 WeakPolarHBondContact O-CG 3.36Å; G274-R278 PolarHBondContact O-N 3.28Å; G274-R278 PolarHBondContact O-NH1 2.91Å; G274-A300 WeakPolarHBondContact CA-O 3.41Å; G274-A300 PolarHBondContact N-O 3.33Å
275Q85.7Confident79.6Confident35 Ų3533.6 Ų33.616%0.16420%0.197CC..Hα-helixtrans-67.8-42.5173.7-75.1167.5-30.100111.6D252 L271 S272 G273 A277 R278 I279D252-Q275 HydrophobicContact CB-CG 4.39Å; D252-Q275 WeakPolarHBondContact OD1-CG 3.12Å; D252-Q275 PolarHBondContact OD1-NE2 3.43Å; L271-Q275 HydrophobicContact CB-CB 4.29Å; S272-Q275 WeakPolarHBondContact O-CB 3.4Å; S272-Q275 PolarHBondContact O-N 3.14Å; S272-Q275 VanDerWaalsContact OG-CD 3.24Å; S272-Q275 VanDerWaalsContact OG-CG 3.24Å; S272-Q275 WeakPolarHBondContact OG-CG 3.47Å; S272-Q275 PolarHBondContact OG-N 3.02Å; S272-Q275 PolarHBondContact OG-OE1 3.15Å; G273-Q275 PolarHBondContact O-N 3.13Å; Q275-A277 VanDerWaalsContact C-N 3.32Å; Q275-A277 PolarHBondContact O-N 2.88Å; Q275-R278 PolarHBondContact O-N 3.1Å; Q275-I279 VanDerWaalsContact O-CG1 3.27Å; Q275-I279 WeakPolarHBondContact O-CG1 3.21Å; Q275-I279 PolarHBondContact O-N 2.6Å
276K86.9Confident80.8Confident40 Ų4032.1 Ų32.117%0.17418%0.181CC..Hα-helixtrans-60.1-44.7175.3-61.7-178.9-170.8-1640111.3A218 L220 K267 G268 L271 S272 G273 I279 N280A218-K276 HydrophobicContact CB-CB 3.59Å; L220-K276 HydrophobicContact CD1-CB 4.24Å; L220-K276 HydrophobicContact CD1-CG 3.95Å; K267-K276 PolarHBondContact O-NZ 3.25Å; G268-K276 WeakPolarHBondContact O-CE 3.4Å; G268-K276 PolarHBondContact O-NZ 2.81Å; L271-K276 HydrophobicContact CB-CG 4.01Å; L271-K276 WeakPolarHBondContact O-CE 3.32Å; S272-K276 WeakPolarHBondContact O-CG 3.36Å; S272-K276 PolarHBondContact O-N 3.31Å; G273-K276 PolarHBondContact O-N 2.95Å; K276-I279 PolarHBondContact O-N 2.89Å; K276-N280 PolarHBondContact O-N 3.07Å
277A86.3Confident82Confident12 Ų1230.9 Ų30.910%0.09917%0.172CC..Hα-helixtrans-59.3-47.5176.900000111.5G273 G274 Q275 I279 N280 L281 A300 V301G273-A277 WeakPolarHBondContact O-CB 3.4Å; G273-A277 PolarHBondContact O-N 2.99Å; G274-A277 PolarHBondContact O-N 3.32Å; Q275-A277 VanDerWaalsContact C-N 3.32Å; Q275-A277 PolarHBondContact O-N 2.88Å; A277-I279 PolarHBondContact O-N 3.43Å; A277-N280 PolarHBondContact O-N 2.86Å; A277-L281 WeakPolarHBondContact O-CB 3.24Å; A277-L281 PolarHBondContact O-N 3.44Å; A277-A300 HydrophobicContact CB-CB 4.4Å; A277-V301 HydrophobicContact CB-CG2 4.39Å
278R90Very high82.9Confident25 Ų2528.6 Ų28.69%0.09417%0.166CC..Hα-helixtrans-62.8-39.5177.1-73.5-171-69.1-86.39.6113.3S247 L249 D252 G274 Q275 L281 A282 V301 I309S247-R278 WeakPolarHBondContact CB-O 3.48Å; S247-R278 WeakPolarHBondContact O-CD 3.38Å; S247-R278 VanDerWaalsContact O-CG 3.23Å; S247-R278 WeakPolarHBondContact O-CG 3.45Å; L249-R278 HydrophobicContact CD1-CB 3.72Å; D252-R278 VanDerWaalsContact CG-NH2 3.25Å; D252-R278 IonicContact OD1-NH2 3.16Å; D252-R278 PolarHBondContact OD1-NH2 2.8Å; D252-R278 IonicContact OD2-CZ 3.36Å; D252-R278 IonicContact OD2-NE 3.47Å; D252-R278 PolarHBondContact OD2-NE 2.82Å; D252-R278 IonicContact OD2-NH2 2.74Å; D252-R278 PolarHBondContact OD2-NH2 3.37Å; G274-R278 WeakPolarHBondContact O-CG 3.36Å; G274-R278 PolarHBondContact O-N 3.28Å; G274-R278 PolarHBondContact O-NH1 2.91Å; Q275-R278 PolarHBondContact O-N 3.1Å; R278-L281 PolarHBondContact O-N 3.36Å; R278-A282 WeakPolarHBondContact O-CB 3.48Å; R278-A282 PolarHBondContact O-N 3.47Å; R278-V301 HydrophobicContact CG-CG2 4.39Å; R278-I309 HydrophobicContact CG-CD1 4.15Å
279I92.1Very high83.9Confident2 Ų228.9 Ų28.91%0.0117%0.169CC..Hα-helixtrans-64.8-41.8175.9-66.8163.4000110.9L220 I225 N228 V229 L249 I264 L271 Q275 K276 A277 A282 R283L220-I279 HydrophobicContact CD1-CD1 4.12Å; L220-I279 HydrophobicContact CD2-CB 4.02Å; L220-I279 HydrophobicContact CD2-CG2 3.47Å; L220-I279 VanDerWaalsContact CD2-CG2 3.47Å; I225-I279 HydrophobicContact CD1-CD1 4.49Å; I225-I279 HydrophobicContact CG1-CD1 4.22Å; I225-I279 HydrophobicContact CG2-CD1 4.19Å; I225-I279 HydrophobicContact CG2-CG1 4.12Å; N228-I279 HydrophobicContact CB-CG2 4.05Å; V229-I279 HydrophobicContact CG2-CG2 4.08Å; L249-I279 HydrophobicContact CD1-CG1 3.78Å; L249-I279 HydrophobicContact CD2-CG1 3.7Å; L249-I279 HydrophobicContact CG-CG1 4.43Å; I264-I279 HydrophobicContact CD1-CD1 4.34Å; L271-I279 HydrophobicContact CD1-CD1 3.47Å; L271-I279 VanDerWaalsContact CD1-CD1 3.47Å; Q275-I279 VanDerWaalsContact O-CG1 3.27Å; Q275-I279 WeakPolarHBondContact O-CG1 3.21Å; Q275-I279 PolarHBondContact O-N 2.6Å; K276-I279 PolarHBondContact O-N 2.89Å; A277-I279 PolarHBondContact O-N 3.43Å; I279-A282 WeakPolarHBondContact O-CB 3.33Å; I279-A282 PolarHBondContact O-N 2.98Å; I279-R283 PolarHBondContact O-N 3.41Å
280N91.2Very high84.6Confident4 Ų430.5 Ų30.52%0.02118%0.175CC..Hα-helixtrans-66.9-37.6175.5-89.65.1000112.9V214 A218 W219 L220 K276 A277 R283 A284V214-N280 HydrophobicContact CG1-CB 4.41Å; A218-N280 WeakPolarHBondContact CA-ND2 3.41Å; W219-N280 PolarHBondContact N-ND2 2.88Å; W219-N280 PolarHBondContact O-ND2 2.77Å; W219-N280 PolarHBondContact O-OD1 2.83Å; L220-N280 WeakPolarHBondContact CD2-OD1 3.43Å; K276-N280 PolarHBondContact O-N 3.07Å; A277-N280 PolarHBondContact O-N 2.86Å; N280-R283 WeakPolarHBondContact O-CB 3.4Å; N280-R283 PolarHBondContact O-N 2.81Å; N280-R283 PolarHBondContact OD1-NH1 3.22Å; N280-R283 VanDerWaalsContact OD1-NH1 3.14Å; N280-R283 PolarHBondContact OD1-NH2 2.97Å; N280-A284 PolarHBondContact O-N 2.77Å
281L91.1Very high85.3Confident4 Ų427.5 Ų27.52%0.02115%0.154CC..Hα-helixtrans-63.8-44.9173.3-17363.9000110.7V214 A277 R278 R283 A284 V285 L294 I309 F313V214-L281 HydrophobicContact CG2-CD1 4.13Å; A277-L281 WeakPolarHBondContact O-CB 3.24Å; A277-L281 PolarHBondContact O-N 3.44Å; R278-L281 PolarHBondContact O-N 3.36Å; L281-R283 VanDerWaalsContact C-N 3.29Å; L281-R283 PolarHBondContact O-N 3.46Å; L281-A284 PolarHBondContact O-N 2.91Å; L281-A284 VanDerWaalsContact O-N 3.13Å; L281-V285 WeakPolarHBondContact O-CG2 3.44Å; L281-V285 PolarHBondContact O-N 2.75Å; L281-L294 HydrophobicContact CD1-CD2 4.16Å; L281-I309 HydrophobicContact CD2-CD1 4.31Å; L281-I309 HydrophobicContact CD2-CG2 3.44Å; L281-I309 VanDerWaalsContact CD2-CG2 3.44Å; L281-F313 HydrophobicContact CD1-CZ 4.06Å; L281-F313 HydrophobicContact CD2-CE2 4.36Å; L281-F313 HydrophobicContact CD2-CZ 4.37Å; L281-F313 HydrophobicContact CG-CZ 4.44Å
282A92.3Very high85.9Confident0 Ų030.9 Ų30.90%017%0.167CC..Hα-helixtrans-57.7-41.7174.600000111.5V229 S247 R278 I279 V285 Y286V229-A282 HydrophobicContact CG1-CB 4.08Å; V229-A282 HydrophobicContact CG2-CB 3.92Å; S247-A282 WeakPolarHBondContact OG-CB 3.45Å; R278-A282 WeakPolarHBondContact O-CB 3.48Å; R278-A282 PolarHBondContact O-N 3.47Å; I279-A282 WeakPolarHBondContact O-CB 3.33Å; I279-A282 PolarHBondContact O-N 2.98Å; A282-V285 PolarHBondContact O-N 3.11Å; A282-Y286 WeakPolarHBondContact O-CB 3.26Å; A282-Y286 PolarHBondContact O-N 3.26Å
283R93Very high86.6Confident29 Ų2930.5 Ų30.511%0.10916%0.162CC..Hα-helixtrans-58-47.6173.7-177.8-168.6-63.3153.33.1111.8W219 N228 F231 I279 N280 L281 Y286 Q287W219-R283 PolarHBondContact O-NH1 2.86Å; W219-R283 PolarHBondContact O-NH2 2.92Å; N228-R283 PolarHBondContact O-NE 3.01Å; N228-R283 PolarHBondContact O-NH2 2.88Å; N228-R283 PolarHBondContact OD1-NH2 3.44Å; N228-R283 VanDerWaalsContact OD1-NH2 3.09Å; F231-R283 HydrophobicContact CB-CG 3.97Å; F231-R283 HydrophobicContact CD2-CG 4.46Å; F231-R283 HydrophobicContact CG-CG 4.3Å; I279-R283 PolarHBondContact O-N 3.41Å; N280-R283 WeakPolarHBondContact O-CB 3.4Å; N280-R283 PolarHBondContact O-N 2.81Å; N280-R283 PolarHBondContact OD1-NH1 3.22Å; N280-R283 VanDerWaalsContact OD1-NH1 3.14Å; N280-R283 PolarHBondContact OD1-NH2 2.97Å; L281-R283 VanDerWaalsContact C-N 3.29Å; L281-R283 PolarHBondContact O-N 3.46Å; R283-Y286 PolarHBondContact O-N 3.26Å; R283-Q287 PolarHBondContact O-N 3.45Å; R283-Q287 VanDerWaalsContact O-N 3.13Å
284A90.1Very high87.4Confident3 Ų331.2 Ų31.23%0.02516%0.156CC..Hα-helixtrans-64.2-47.9179.700000111.5A212 V214 N280 L281 Y286 Q287 Y292A212-A284 HydrophobicContact CB-CB 4.15Å; V214-A284 HydrophobicContact CG2-CB 3.34Å; N280-A284 PolarHBondContact O-N 2.77Å; L281-A284 PolarHBondContact O-N 2.91Å; L281-A284 VanDerWaalsContact O-N 3.13Å; A284-Y286 VanDerWaalsContact C-N 3.31Å; A284-Y286 PolarHBondContact O-N 3.48Å; A284-Q287 WeakPolarHBondContact O-CB 3.41Å; A284-Q287 PolarHBondContact O-N 3.08Å; A284-Q287 VanDerWaalsContact O-N 3.09Å; A284-Y292 VanDerWaalsContact O-CE1 3.3Å; A284-Y292 WeakPolarHBondContact O-CE1 3.45Å
285V90.3Very high87.7Confident29 Ų2931.8 Ų31.818%0.17616%0.158CC..Hα-helixtrans-59.8-42.8177.3174.90000110.9A243 V246 L281 A282 Q287 D288 F313A243-V285 HydrophobicContact CB-CB 4.28Å; A243-V285 HydrophobicContact CB-CG1 4.01Å; V246-V285 HydrophobicContact CG1-CG2 4.23Å; L281-V285 WeakPolarHBondContact O-CG2 3.44Å; L281-V285 PolarHBondContact O-N 2.75Å; A282-V285 PolarHBondContact O-N 3.11Å; V285-Q287 PolarHBondContact O-N 3.41Å; V285-D288 PolarHBondContact O-N 2.97Å; V285-F313 HydrophobicContact CG2-CE1 4.01Å; V285-F313 HydrophobicContact CG2-CZ 4.04Å
286Y91.9Very high87.3Confident3 Ų334 Ų341%0.01217%0.171CC..Hα-helixtrans-64.5-24.6177.9-167.9-100.7000113.1V229 L230 Q233 D234 M235 D236 R239 Y240 A243 A282 R283 A284 D288V229-Y286 HydrophobicContact CG1-CG 4.36Å; L230-Y286 HydrophobicContact CD2-CD1 4.09Å; L230-Y286 HydrophobicContact CD2-CE1 3.36Å; L230-Y286 HydrophobicContact CD2-CE2 4.07Å; L230-Y286 WeakPolarHBondContact CD2-OH 3.48Å; Q233-Y286 HydrophobicContact CB-CE1 4.07Å; D234-Y286 PolarHBondContact O-OH 3.35Å; M235-Y286 WeakPolarHBondContact CA-OH 3.27Å; D236-Y286 PolarHBondContact N-OH 2.95Å; R239-Y286 HydrophobicContact CB-CD2 4.45Å; R239-Y286 HydrophobicContact CB-CE2 4.02Å; R239-Y286 HydrophobicContact CG-CD2 3.85Å; R239-Y286 HydrophobicContact CG-CE2 3.8Å; R239-Y286 PolarHBondContact NE-O 3.35Å; R239-Y286 PolarHBondContact NH2-O 2.95Å; Y240-Y286 HydrophobicContact CD2-CD2 4.38Å; Y240-Y286 HydrophobicContact CD2-CE2 4.3Å; A243-Y286 HydrophobicContact CB-CD2 4.21Å; A282-Y286 WeakPolarHBondContact O-CB 3.26Å; A282-Y286 PolarHBondContact O-N 3.26Å; R283-Y286 PolarHBondContact O-N 3.26Å; A284-Y286 VanDerWaalsContact C-N 3.31Å; A284-Y286 PolarHBondContact O-N 3.48Å; Y286-D288 VanDerWaalsContact C-N 3.33Å; Y286-D288 PolarHBondContact O-N 3.48Å
287Q87.3Confident86.7Confident67 Ų6733.3 Ų33.331%0.31317%0.17SC..Hα-helixtrans-71.7-23.6-179.3-167.8-179.4-14.900113.5I211 A212 R239 R283 A284 V285I211-Q287 PolarHBondContact O-NE2 3.27Å; A212-Q287 HydrophobicContact CB-CB 4.49Å; R239-Q287 PolarHBondContact NH2-O 3.03Å; R283-Q287 PolarHBondContact O-N 3.45Å; R283-Q287 VanDerWaalsContact O-N 3.13Å; A284-Q287 WeakPolarHBondContact O-CB 3.41Å; A284-Q287 PolarHBondContact O-N 3.08Å; A284-Q287 VanDerWaalsContact O-N 3.09Å; V285-Q287 PolarHBondContact O-N 3.41Å
288D83.8Confident86.3Confident79 Ų7934.1 Ų34.142%0.42217%0.173SC..  trans48.966.2-177.8-170.631.4000112.8R210 R239 V285 Y286 Y292R210-D288 PolarHBondContact NH2-O 2.83Å; R239-D288 IonicContact CZ-OD2 3.42Å; R239-D288 IonicContact NH1-OD2 3.23Å; R239-D288 PolarHBondContact NH1-OD2 2.94Å; V285-D288 PolarHBondContact O-N 2.97Å; Y286-D288 VanDerWaalsContact C-N 3.33Å; Y286-D288 PolarHBondContact O-N 3.48Å; D288-Y292 VanDerWaalsContact CA-OH 3.27Å; D288-Y292 WeakPolarHBondContact CA-OH 3.4Å
289A82.9Confident85.4Confident7 Ų736 Ų366%0.05819%0.19CC..  trans-89.9160.9178.700000111.8R210 A212 I291 Y292R210-A289 HydrophobicContact CB-CB 4.38Å; R210-A289 WeakPolarHBondContact O-CB 3.2Å; A212-A289 HydrophobicContact CB-CB 3.46Å; A212-A289 VanDerWaalsContact CB-CB 3.46Å; A212-A289 VanDerWaalsContact N-CB 3.25Å; A289-I291 VanDerWaalsContact C-N 3.34Å; A289-Y292 HydrophobicContact CB-CE2 4.4Å; A289-Y292 PolarHBondContact N-OH 3.3Å; A289-Y292 WeakPolarHBondContact O-CE2 3.42Å
290D77.5Confident84.2Confident107 Ų10737.5 Ų37.557%0.57220%0.202SC*.SBendtrans-76.9-26.8174.9-52.4-58.5000111.4G209 R210G209-D290 WeakPolarHBondContact CA-OD2 3.5Å; R210-D290 PolarHBondContact N-OD2 2.77Å; R210-D290 PolarHBondContact O-N 3.1Å
291I82.1Confident83.2Confident41 Ų4137.8 Ų37.821%0.2121%0.205CC..EExtended strand (participates in β ladder)trans-131.3126.6-176.7-56.6172.6000109V207 R210 I211 A212 A289 L293V207-I291 HydrophobicContact CG1-CD1 3.43Å; V207-I291 VanDerWaalsContact CG1-CD1 3.43Å; R210-I291 PolarHBondContact O-N 2.78Å; I211-I291 CarbonylContact C-O 3.58Å; I211-I291 WeakPolarHBondContact CA-O 3.02Å; I211-I291 HydrophobicContact CG1-CB 4.32Å; I211-I291 HydrophobicContact CG1-CD1 4.48Å; A212-I291 PolarHBondContact N-O 3.09Å; A289-I291 VanDerWaalsContact C-N 3.34Å; I291-L293 HydrophobicContact CG2-CD2 3.99Å; I291-L293 HydrophobicContact CG2-CG 4.32Å
292Y86Confident82Confident88 Ų8839 Ų3935%0.34521%0.211SC..EExtended strand (participates in β ladder)trans-108.6117.8174.7-70.7-98000109.9A212 A284 D288 A289A212-Y292 HydrophobicContact CB-CD1 3.74Å; A212-Y292 HydrophobicContact CB-CE1 3.81Å; A212-Y292 HydrophobicContact CB-CG 4.44Å; A212-Y292 WeakPolarHBondContact O-CA 3.31Å; A284-Y292 VanDerWaalsContact O-CE1 3.3Å; A284-Y292 WeakPolarHBondContact O-CE1 3.45Å; D288-Y292 VanDerWaalsContact CA-OH 3.27Å; D288-Y292 WeakPolarHBondContact CA-OH 3.4Å; A289-Y292 HydrophobicContact CB-CE2 4.4Å; A289-Y292 PolarHBondContact N-OH 3.3Å; A289-Y292 WeakPolarHBondContact O-CE2 3.42Å
293L88.3Confident80.8Confident18 Ų1841.8 Ų41.89%0.09423%0.228CC..EExtended strand (participates in β ladder)trans-103.6109.8173.3-60.4-175.6000108.1L191 L194 L195 I211 A212 Y213 V214 I291L191-L293 HydrophobicContact CD2-CB 4.44Å; L191-L293 HydrophobicContact CD2-CD2 4.18Å; L194-L293 HydrophobicContact CB-CD1 4.06Å; L194-L293 HydrophobicContact CD1-CD1 4.46Å; L194-L293 HydrophobicContact CD1-CD2 3.98Å; L195-L293 HydrophobicContact CD2-CD1 3.94Å; L195-L293 HydrophobicContact CG-CD1 3.98Å; I211-L293 HydrophobicContact CG2-CD1 3.73Å; I211-L293 HydrophobicContact CG2-CG 3.81Å; A212-L293 PolarHBondContact O-N 3.41Å; Y213-L293 WeakPolarHBondContact CA-O 3.47Å; Y213-L293 HydrophobicContact CD2-CB 3.84Å; Y213-L293 WeakPolarHBondContact CD2-O 3.37Å; V214-L293 PolarHBondContact N-O 3.43Å; I291-L293 HydrophobicContact CG2-CD2 3.99Å; I291-L293 HydrophobicContact CG2-CG 4.32Å
294L87.8Confident79.8Confident60 Ų6042.7 Ų42.731%0.31424%0.242SC..EExtended strand (participates in β ladder)trans-112.9105.1-176.1-51.1178.3000109.6V214 L281 D296 P297V214-L294 HydrophobicContact CB-CD2 3.82Å; V214-L294 HydrophobicContact CG2-CD2 3.46Å; V214-L294 VanDerWaalsContact CG2-CD2 3.46Å; L281-L294 HydrophobicContact CD1-CD2 4.16Å; L294-D296 PolarHBondContact O-N 2.91Å; L294-P297 HydrophobicContact CB-CB 4.38Å; L294-P297 HydrophobicContact CB-CG 3.77Å; L294-P297 HydrophobicContact CD1-CG 4.33Å
295D84.7Confident79.1Confident14 Ų1443.3 Ų43.38%0.07525%0.245CC..SBendtrans-9092.9179.1-1637.8000109.6S188 L191 Y213 V214 Q216S188-D295 WeakPolarHBondContact CB-OD2 3.49Å; S188-D295 PolarHBondContact OG-OD1 2.96Å; S188-D295 PolarHBondContact OG-OD2 3.43Å; L191-D295 HydrophobicContact CD1-CB 3.56Å; Y213-D295 HydrophobicContact CE2-CB 4.08Å; V214-D295 WeakPolarHBondContact O-CB 3.3Å; V214-D295 PolarHBondContact O-N 2.96Å; Q216-D295 WeakPolarHBondContact CA-O 3.38Å; Q216-D295 HydrophobicContact CB-CB 4.31Å; Q216-D295 PolarHBondContact N-O 2.99Å
296D77.7Confident78.4Confident82 Ų8242 Ų4244%0.43924%0.237SC..SBendtrans50.252.8179.5-156.74000115.5Q216 L294 L298 S299Q216-D296 HydrophobicContact CG-CB 4.41Å; L294-D296 PolarHBondContact O-N 2.91Å; D296-L298 PolarHBondContact O-N 3.46Å; D296-L298 VanDerWaalsContact O-N 3.15Å; D296-S299 PolarHBondContact O-N 3.17Å; D296-S299 PolarHBondContact O-OG 3.11Å
297P75.4Confident77.5Confident26 Ų2645.1 Ų45.117%0.16925%0.251CS..THydrogen-bonded Turntrans-67.8-16.4-17131.9-40.8000114.4V214 L294V214-P297 HydrophobicContact CG1-CB 4.16Å; L294-P297 HydrophobicContact CB-CB 4.38Å; L294-P297 HydrophobicContact CB-CG 3.77Å; L294-P297 HydrophobicContact CD1-CG 4.33Å
298L77.1Confident77Confident28 Ų2844.6 Ų44.615%0.14726%0.255CS..THydrogen-bonded Turntrans-103.4-5.9-173.7-57.7-177.2000113.4D296 A300 V301 I309 Y318D296-L298 PolarHBondContact O-N 3.46Å; D296-L298 VanDerWaalsContact O-N 3.15Å; L298-A300 VanDerWaalsContact C-N 3.29Å; L298-A300 PolarHBondContact O-N 2.98Å; L298-V301 PolarHBondContact O-N 2.95Å; L298-I309 HydrophobicContact CD2-CB 4.21Å; L298-I309 HydrophobicContact CD2-CD1 4.32Å; L298-I309 HydrophobicContact CD2-CG2 3.88Å; L298-Y318 HydrophobicContact CD1-CD2 4.36Å; L298-Y318 HydrophobicContact CD1-CE2 3.71Å
299S71.5Confident76.8Confident64 Ų6441 Ų4145%0.44824%0.235SC..THydrogen-bonded Turntrans-54.6-38.6-175.252.60000114.8D296D296-S299 PolarHBondContact O-N 3.17Å; D296-S299 PolarHBondContact O-OG 3.11Å
300A66.5Low76.5Confident34 Ų3441.9 Ų41.928%0.28124%0.238SC..THydrogen-bonded Turntrans-93.92.9-177.700000113.8G274 A277 L298G274-A300 WeakPolarHBondContact CA-O 3.41Å; G274-A300 PolarHBondContact N-O 3.33Å; A277-A300 HydrophobicContact CB-CB 4.4Å; L298-A300 VanDerWaalsContact C-N 3.29Å; L298-A300 PolarHBondContact O-N 2.98Å
301V70.4Confident76.4Confident11 Ų1140.9 Ų40.97%0.06723%0.23CC..SBendtrans-105143.1-173.9-175.70000109.1A277 R278 L298 V305 I309A277-V301 HydrophobicContact CB-CG2 4.39Å; R278-V301 HydrophobicContact CG-CG2 4.39Å; L298-V301 PolarHBondContact O-N 2.95Å; V301-V305 HydrophobicContact CG1-CB 3.47Å; V301-V305 VanDerWaalsContact CG1-CB 3.47Å; V301-V305 HydrophobicContact CG1-CG1 3.4Å; V301-I309 HydrophobicContact CG1-CD1 4.29Å
302D66Low76.1Confident30 Ų3041.5 Ų41.516%0.1624%0.238CC..  trans-64.9154.9176.364.923.1000110.8A304 V305 G306 R679D302-A304 PolarHBondContact O-N 3.44Å; D302-V305 PolarHBondContact O-N 3.45Å; D302-V305 WeakPolarHBondContact OD1-CA 3.41Å; D302-V305 WeakPolarHBondContact OD1-CB 3.45Å; D302-V305 WeakPolarHBondContact OD1-CG2 3.29Å; D302-V305 PolarHBondContact OD1-N 3.41Å; D302-G306 PolarHBondContact O-N 3.08Å; D302-R679 IonicContact OD2-CZ 3.9Å; D302-R679 IonicContact OD2-NE 2.72Å; D302-R679 IonicContact OD2-NH2 3.58Å; D302-R679 PolarHBondContact OD2-NH2 2.94Å
303T67.1Low75.3Confident57 Ų5740.3 Ų40.335%0.3523%0.234SC..Hα-helixtrans-57.2-37-174-44.80000112.3G306 K307 Y318 E878T303-G306 PolarHBondContact O-N 3.36Å; T303-K307 WeakPolarHBondContact O-CB 3.4Å; T303-K307 PolarHBondContact O-N 3.3Å; T303-Y318 HydrophobicContact CG2-CE1 3.86Å; T303-E878 WeakPolarHBondContact CB-O 3.47Å; T303-E878 WeakPolarHBondContact CG2-O 3.35Å
304A70.5Confident74Confident48 Ų4842.6 Ų42.640%0.39726%0.262SS..Hα-helixtrans-68-45.5-179.800000112.5D302 S308D302-A304 PolarHBondContact O-N 3.44Å; A304-S308 PolarHBondContact O-N 2.99Å
305V76.9Confident72.6Confident16 Ų1646.3 Ų46.310%0.09727%0.273CS..Hα-helixtrans-71.2-36.9175.7177.30000110.2A248 V301 D302 K307 S308 I309A248-V305 HydrophobicContact CB-CG1 3.73Å; V301-V305 HydrophobicContact CG1-CB 3.47Å; V301-V305 VanDerWaalsContact CG1-CB 3.47Å; V301-V305 HydrophobicContact CG1-CG1 3.4Å; D302-V305 PolarHBondContact O-N 3.45Å; D302-V305 WeakPolarHBondContact OD1-CA 3.41Å; D302-V305 WeakPolarHBondContact OD1-CB 3.45Å; D302-V305 WeakPolarHBondContact OD1-CG2 3.29Å; D302-V305 PolarHBondContact OD1-N 3.41Å; V305-K307 VanDerWaalsContact C-N 3.34Å; V305-K307 PolarHBondContact O-N 2.89Å; V305-S308 PolarHBondContact O-N 3.12Å; V305-I309 HydrophobicContact CG1-CD1 3.73Å; V305-I309 HydrophobicContact CG1-CG1 4.15Å; V305-I309 WeakPolarHBondContact O-CB 3.44Å; V305-I309 VanDerWaalsContact O-CG1 3.26Å; V305-I309 WeakPolarHBondContact O-CG1 3.39Å; V305-I309 PolarHBondContact O-N 3.39Å
306G74.8Confident71.1Confident1 Ų147 Ų471%0.0128%0.284CS..Hα-helixtrans-58.3-44.7173.600000112.3D302 T303 I309 F310D302-G306 PolarHBondContact O-N 3.08Å; T303-G306 PolarHBondContact O-N 3.36Å; G306-I309 PolarHBondContact O-N 2.92Å; G306-F310 WeakPolarHBondContact O-CB 3.43Å; G306-F310 PolarHBondContact O-N 3.44Å
307K72.5Confident69.8Low70 Ų7045.8 Ų45.830%0.30428%0.279SS..Hα-helixtrans-59.9-49.9173.2-178.9167.6-178.7171.60111.8T303 V305 I309 F310 E311 Y318 E319T303-K307 WeakPolarHBondContact O-CB 3.4Å; T303-K307 PolarHBondContact O-N 3.3Å; V305-K307 VanDerWaalsContact C-N 3.34Å; V305-K307 PolarHBondContact O-N 2.89Å; K307-I309 PolarHBondContact O-N 2.97Å; K307-F310 PolarHBondContact O-N 3.5Å; K307-E311 WeakPolarHBondContact CE-OE1 3.3Å; K307-E311 HydrophobicContact CG-CG 4.37Å; K307-E311 WeakPolarHBondContact CG-OE1 3.32Å; K307-E311 IonicContact NZ-OE1 2.7Å; K307-E311 WeakPolarHBondContact O-CB 3.49Å; K307-E311 WeakPolarHBondContact O-CG 3.49Å; K307-E311 PolarHBondContact O-N 2.95Å; K307-Y318 HydrophobicContact CB-CD1 3.75Å; K307-Y318 HydrophobicContact CB-CE1 4.4Å; K307-Y318 HydrophobicContact CB-CG 4.04Å; K307-Y318 HydrophobicContact CG-CD1 4.27Å; K307-Y318 HydrophobicContact CG-CG 4.37Å; K307-E319 IonicContact NZ-OE1 3.71Å; K307-E319 PolarHBondContact NZ-OE1 3.26Å
308S77Confident68.8Low56 Ų5646.2 Ų46.239%0.39228%0.278SS..Hα-helixtrans-58.2-45.8178-1760000112.2A304 V305 S312A304-S308 PolarHBondContact O-N 2.99Å; V305-S308 PolarHBondContact O-N 3.12Å; S308-S312 WeakPolarHBondContact O-CB 3.45Å; S308-S312 PolarHBondContact O-N 3.35Å; S308-S312 PolarHBondContact O-OG 3.04Å
309I80.7Confident67.6Low2 Ų250.4 Ų50.41%0.0130%0.296CS..Hα-helixtrans-63-46.9179.2-71171.8000110.2A248 R278 L281 L298 V301 V305 G306 K307 S312 F313A248-I309 HydrophobicContact CB-CD1 4.44Å; A248-I309 HydrophobicContact CB-CG1 4.07Å; R278-I309 HydrophobicContact CG-CD1 4.15Å; L281-I309 HydrophobicContact CD2-CD1 4.31Å; L281-I309 HydrophobicContact CD2-CG2 3.44Å; L281-I309 VanDerWaalsContact CD2-CG2 3.44Å; L298-I309 HydrophobicContact CD2-CB 4.21Å; L298-I309 HydrophobicContact CD2-CD1 4.32Å; L298-I309 HydrophobicContact CD2-CG2 3.88Å; V301-I309 HydrophobicContact CG1-CD1 4.29Å; V305-I309 HydrophobicContact CG1-CD1 3.73Å; V305-I309 HydrophobicContact CG1-CG1 4.15Å; V305-I309 WeakPolarHBondContact O-CB 3.44Å; V305-I309 VanDerWaalsContact O-CG1 3.26Å; V305-I309 WeakPolarHBondContact O-CG1 3.39Å; V305-I309 PolarHBondContact O-N 3.39Å; G306-I309 PolarHBondContact O-N 2.92Å; K307-I309 PolarHBondContact O-N 2.97Å; I309-S312 PolarHBondContact O-N 3.22Å; I309-F313 HydrophobicContact CG2-CD2 4.32Å; I309-F313 HydrophobicContact CG2-CE2 3.69Å; I309-F313 WeakPolarHBondContact O-CD2 3.44Å; I309-F313 PolarHBondContact O-N 3.09Å
310F76.6Confident66.7Low26 Ų2653.1 Ų53.111%0.11430%0.302CS..Hα-helixtrans-63.7-44.7-178.9-170.9-95000112.1L176 G306 K307 S312 F313 G316 Y318 L321L176-F310 HydrophobicContact CD2-CE2 4.15Å; L176-F310 HydrophobicContact CD2-CZ 3.94Å; G306-F310 WeakPolarHBondContact O-CB 3.43Å; G306-F310 PolarHBondContact O-N 3.44Å; K307-F310 PolarHBondContact O-N 3.5Å; F310-S312 VanDerWaalsContact C-N 3.32Å; F310-S312 PolarHBondContact O-N 3.1Å; F310-F313 PolarHBondContact O-N 2.97Å; F310-F313 VanDerWaalsContact O-N 3.15Å; F310-G316 WeakPolarHBondContact CE1-O 3.43Å; F310-Y318 HydrophobicContact CB-CD2 3.76Å; F310-Y318 HydrophobicContact CB-CG 4.43Å; F310-Y318 HydrophobicContact CD1-CD2 4.36Å; F310-Y318 AromaticContact CG-CD2 3.96Å; F310-Y318 HydrophobicContact CG-CD2 3.96Å; F310-L321 HydrophobicContact CD2-CD2 4.14Å; F310-L321 HydrophobicContact CE1-CB 4.33Å; F310-L321 HydrophobicContact CE2-CB 4.29Å; F310-L321 HydrophobicContact CE2-CD1 3.76Å; F310-L321 HydrophobicContact CE2-CD2 3.9Å; F310-L321 HydrophobicContact CE2-CG 4.2Å; F310-L321 HydrophobicContact CZ-CB 3.97Å; F310-L321 HydrophobicContact CZ-CD1 3.88Å; F310-L321 HydrophobicContact CZ-CD2 4.42Å; F310-L321 HydrophobicContact CZ-CG 4.31Å
311E75.7Confident66.1Low87 Ų8754.2 Ų54.241%0.40730%0.303SS..Hα-helixtrans-65.2-34.3177.4-72175.2174.600112K307 F313 G314K307-E311 WeakPolarHBondContact CE-OE1 3.3Å; K307-E311 HydrophobicContact CG-CG 4.37Å; K307-E311 WeakPolarHBondContact CG-OE1 3.32Å; K307-E311 IonicContact NZ-OE1 2.7Å; K307-E311 WeakPolarHBondContact O-CB 3.49Å; K307-E311 WeakPolarHBondContact O-CG 3.49Å; K307-E311 PolarHBondContact O-N 2.95Å; E311-F313 PolarHBondContact O-N 3.38Å; E311-G314 PolarHBondContact O-N 2.99Å
312S74.6Confident65.2Low53 Ų5357.1 Ų57.137%0.37132%0.317SS..Hα-helixtrans-62-21.9173.8-66.60000113.8S308 I309 F310S308-S312 WeakPolarHBondContact O-CB 3.45Å; S308-S312 PolarHBondContact O-N 3.35Å; S308-S312 PolarHBondContact O-OG 3.04Å; I309-S312 PolarHBondContact O-N 3.22Å; F310-S312 VanDerWaalsContact C-N 3.32Å; F310-S312 PolarHBondContact O-N 3.1Å
313F70Confident64.2Low63 Ų6359 Ų5928%0.27634%0.337SS..THydrogen-bonded Turntrans-80.1-16.7173.5-71.2-73.1000113.6V246 L281 V285 I309 F310 E311 Y315V246-F313 HydrophobicContact CG1-CD1 4.41Å; V246-F313 HydrophobicContact CG1-CE1 3.95Å; V246-F313 HydrophobicContact CG1-CE2 4.28Å; V246-F313 HydrophobicContact CG1-CZ 3.87Å; L281-F313 HydrophobicContact CD1-CZ 4.06Å; L281-F313 HydrophobicContact CD2-CE2 4.36Å; L281-F313 HydrophobicContact CD2-CZ 4.37Å; L281-F313 HydrophobicContact CG-CZ 4.44Å; V285-F313 HydrophobicContact CG2-CE1 4.01Å; V285-F313 HydrophobicContact CG2-CZ 4.04Å; I309-F313 HydrophobicContact CG2-CD2 4.32Å; I309-F313 HydrophobicContact CG2-CE2 3.69Å; I309-F313 WeakPolarHBondContact O-CD2 3.44Å; I309-F313 PolarHBondContact O-N 3.09Å; F310-F313 PolarHBondContact O-N 2.97Å; F310-F313 VanDerWaalsContact O-N 3.15Å; E311-F313 PolarHBondContact O-N 3.38Å; F313-Y315 HydrophobicContact CB-CD2 3.86Å; F313-Y315 HydrophobicContact CB-CE2 4.24Å; F313-Y315 WeakPolarHBondContact O-CD2 3.38Å; F313-Y315 VanDerWaalsContact O-CE2 3.26Å; F313-Y315 WeakPolarHBondContact O-CE2 3.47Å; F313-Y315 PolarHBondContact O-N 3.15Å
314G59.8Low63.4Low66 Ų6658.8 Ų58.868%0.6834%0.336SS*.THydrogen-bonded Turntrans75.811.7171.600000117.1E311E311-G314 PolarHBondContact O-N 2.99Å
315Y59.1Low62.1Low139 Ų13958.7 Ų58.755%0.54534%0.339SS..SBendtrans-95.21.5-175.6-67.1-76.7000115.6L176 F313L176-Y315 HydrophobicContact CB-CD1 4.34Å; L176-Y315 HydrophobicContact CB-CG 4.27Å; L176-Y315 HydrophobicContact CD2-CG 4.47Å; F313-Y315 HydrophobicContact CB-CD2 3.86Å; F313-Y315 HydrophobicContact CB-CE2 4.24Å; F313-Y315 WeakPolarHBondContact O-CD2 3.38Å; F313-Y315 VanDerWaalsContact O-CE2 3.26Å; F313-Y315 WeakPolarHBondContact O-CE2 3.47Å; F313-Y315 PolarHBondContact O-N 3.15Å
316G54.2Low60.2Low29 Ų2964.2 Ų64.230%0.29937%0.368SS..SBendtrans151.9-177.9-179.300000112.2F310F310-G316 WeakPolarHBondContact CE1-O 3.43Å
317T50.2Low58Low55 Ų5572.6 Ų72.634%0.33741%0.407SS..  trans-87.7143.7173.5630000110.5E319 Q320 L321T317-E319 PolarHBondContact O-N 3.14Å; T317-E319 VanDerWaalsContact O-N 3.15Å; T317-Q320 WeakPolarHBondContact O-CB 3.46Å; T317-Q320 PolarHBondContact O-N 3.02Å; T317-Q320 VanDerWaalsContact OG1-CG 3.31Å; T317-Q320 WeakPolarHBondContact OG1-CG 3.27Å; T317-Q320 PolarHBondContact OG1-N 3.4Å; T317-L321 PolarHBondContact O-N 3.05Å
318Y52.8Low56.1Low35 Ų3575 Ų7514%0.13742%0.418CS..Hα-helixtrans-57.9-28.5175.1-174.4-115.2000112.1L298 T303 K307 F310 L321 I322L298-Y318 HydrophobicContact CD1-CD2 4.36Å; L298-Y318 HydrophobicContact CD1-CE2 3.71Å; T303-Y318 HydrophobicContact CG2-CE1 3.86Å; K307-Y318 HydrophobicContact CB-CD1 3.75Å; K307-Y318 HydrophobicContact CB-CE1 4.4Å; K307-Y318 HydrophobicContact CB-CG 4.04Å; K307-Y318 HydrophobicContact CG-CD1 4.27Å; K307-Y318 HydrophobicContact CG-CG 4.37Å; F310-Y318 HydrophobicContact CB-CD2 3.76Å; F310-Y318 HydrophobicContact CB-CG 4.43Å; F310-Y318 HydrophobicContact CD1-CD2 4.36Å; F310-Y318 AromaticContact CG-CD2 3.96Å; F310-Y318 HydrophobicContact CG-CD2 3.96Å; Y318-L321 HydrophobicContact CD2-CD2 4.32Å; Y318-L321 HydrophobicContact CE2-CD2 4.28Å; Y318-L321 WeakPolarHBondContact O-CB 3.4Å; Y318-L321 PolarHBondContact O-N 3.29Å; Y318-I322 HydrophobicContact CD1-CD1 3.48Å; Y318-I322 VanDerWaalsContact CD1-CD1 3.48Å; Y318-I322 HydrophobicContact CD1-CG1 4.23Å; Y318-I322 HydrophobicContact CE1-CD1 3.1Å; Y318-I322 HydrophobicContact CE1-CG1 3.95Å; Y318-I322 HydrophobicContact CE2-CD1 4.48Å; Y318-I322 HydrophobicContact CG-CD1 4.34Å; Y318-I322 WeakPolarHBondContact O-CG1 3.15Å; Y318-I322 PolarHBondContact O-N 3.24Å
319E53.1Low53.6Low116 Ų11678.4 Ų78.454%0.54244%0.436SS..Hα-helixtrans-64.1-37.2173.6-71.6157.1-155.600112.6K307 T317 A323K307-E319 IonicContact NZ-OE1 3.71Å; K307-E319 PolarHBondContact NZ-OE1 3.26Å; T317-E319 PolarHBondContact O-N 3.14Å; T317-E319 VanDerWaalsContact O-N 3.15Å; E319-A323 WeakPolarHBondContact O-CB 3.36Å; E319-A323 PolarHBondContact O-N 3.19Å
320Q53.3Low51Low122 Ų12286.5 Ų86.557%0.5747%0.474SS*.Hα-helixtrans-66.1-39.9173.1-73.6166.3-1600111.3T317 T324T317-Q320 WeakPolarHBondContact O-CB 3.46Å; T317-Q320 PolarHBondContact O-N 3.02Å; T317-Q320 VanDerWaalsContact OG1-CG 3.31Å; T317-Q320 WeakPolarHBondContact OG1-CG 3.27Å; T317-Q320 PolarHBondContact OG1-N 3.4Å; Q320-T324 WeakPolarHBondContact O-CG2 3.26Å; Q320-T324 PolarHBondContact O-N 3.22Å
321L53.4Low48.6Very low57 Ų5791.6 Ų91.630%0.29850%0.501SS..Hα-helixtrans-64.3-47.9175.6-16990.9000111.1F310 T317 Y318 A323 T324F310-L321 HydrophobicContact CD2-CD2 4.14Å; F310-L321 HydrophobicContact CE1-CB 4.33Å; F310-L321 HydrophobicContact CE2-CB 4.29Å; F310-L321 HydrophobicContact CE2-CD1 3.76Å; F310-L321 HydrophobicContact CE2-CD2 3.9Å; F310-L321 HydrophobicContact CE2-CG 4.2Å; F310-L321 HydrophobicContact CZ-CB 3.97Å; F310-L321 HydrophobicContact CZ-CD1 3.88Å; F310-L321 HydrophobicContact CZ-CD2 4.42Å; F310-L321 HydrophobicContact CZ-CG 4.31Å; T317-L321 PolarHBondContact O-N 3.05Å; Y318-L321 HydrophobicContact CD2-CD2 4.32Å; Y318-L321 HydrophobicContact CE2-CD2 4.28Å; Y318-L321 WeakPolarHBondContact O-CB 3.4Å; Y318-L321 PolarHBondContact O-N 3.29Å; L321-A323 PolarHBondContact O-N 3.48Å; L321-T324 PolarHBondContact O-N 3.5Å; L321-T324 PolarHBondContact O-OG1 3.02Å
322I51.9Low46.3Very low72 Ų7295.9 Ų95.937%0.36953%0.526SS..Hα-helixtrans-63.2-41.2177.7-70.6174.5000111.2Y318 T324 G325Y318-I322 HydrophobicContact CD1-CD1 3.48Å; Y318-I322 VanDerWaalsContact CD1-CD1 3.48Å; Y318-I322 HydrophobicContact CD1-CG1 4.23Å; Y318-I322 HydrophobicContact CE1-CD1 3.1Å; Y318-I322 HydrophobicContact CE1-CG1 3.95Å; Y318-I322 HydrophobicContact CE2-CD1 4.48Å; Y318-I322 HydrophobicContact CG-CD1 4.34Å; Y318-I322 WeakPolarHBondContact O-CG1 3.15Å; Y318-I322 PolarHBondContact O-N 3.24Å; I322-T324 PolarHBondContact O-N 2.85Å; I322-T324 VanDerWaalsContact O-N 3.14Å; I322-G325 WeakPolarHBondContact O-CA 3.23Å; I322-G325 PolarHBondContact O-N 3.1Å
323A44.8Very low44.1Very low68 Ų68101.1 Ų101.156%0.56254%0.544SS*.Hα-helixtrans-58.6-28.9179.200000112.5E319 L321 G325 F328E319-A323 WeakPolarHBondContact O-CB 3.36Å; E319-A323 PolarHBondContact O-N 3.19Å; L321-A323 PolarHBondContact O-N 3.48Å; A323-G325 VanDerWaalsContact C-N 3.28Å; A323-G325 PolarHBondContact O-N 3.23Å; A323-F328 WeakPolarHBondContact O-CE2 3.3Å
324T50Low42Very low54 Ų54107 Ų10733%0.33157%0.572SS.*THydrogen-bonded Turntrans-74.2-14.4173.664.40000114.6Q320 L321 I322 F328Q320-T324 WeakPolarHBondContact O-CG2 3.26Å; Q320-T324 PolarHBondContact O-N 3.22Å; L321-T324 PolarHBondContact O-N 3.5Å; L321-T324 PolarHBondContact O-OG1 3.02Å; I322-T324 PolarHBondContact O-N 2.85Å; I322-T324 VanDerWaalsContact O-N 3.14Å; T324-F328 HydrophobicContact CG2-CE2 4.41Å; T324-F328 WeakPolarHBondContact O-CD2 3.5Å
325G42.1Very low40.5Very low46 Ų46110.3 Ų110.347%0.47458%0.58SS.*THydrogen-bonded Turntrans-89.3-21.5-167.700000116.6I322 A323I322-G325 WeakPolarHBondContact O-CA 3.23Å; I322-G325 PolarHBondContact O-N 3.1Å; A323-G325 VanDerWaalsContact C-N 3.28Å; A323-G325 PolarHBondContact O-N 3.23Å
326D37.8Very low38.8Very low132 Ų132113 Ų11371%0.70660%0.598SS**SBendtrans-102.2-24.6-169-82.1-18.7000115.4
327Q27.8Very low37.5Very low177 Ų177118.5 Ų118.583%0.82762%0.619SS**  trans-157.984.9176.9-66.1-175.2-2.900112.9
328F32.7Very low36.2Very low119 Ų119120.9 Ų120.952%0.52264%0.638SS.*  trans-12684.5172.1-90.9-92.9000112.9A323 T324 I331A323-F328 WeakPolarHBondContact O-CE2 3.3Å; T324-F328 HydrophobicContact CG2-CE2 4.41Å; T324-F328 WeakPolarHBondContact O-CD2 3.5Å; F328-I331 HydrophobicContact CD1-CB 4.44Å; F328-I331 HydrophobicContact CD1-CD1 4.48Å; F328-I331 HydrophobicContact CE1-CB 4.14Å; F328-I331 HydrophobicContact CE1-CD1 3.66Å; F328-I331 HydrophobicContact CE1-CG1 4.46Å; F328-I331 HydrophobicContact CZ-CD1 4.4Å
329T25Very low34.9Very low128 Ų128129 Ų12979%0.78567%0.67SS**SBendtrans-110.6123.1148.144.30000105.5
330H25.9Very low33.5Very low173 Ų173132.4 Ų132.480%0.80169%0.686SS**  trans80.297.5-166.8-60.6-88.1000115.2
331I27.1Very low32.2Very low133 Ų133130 Ų13068%0.68269%0.693SS**  -171.783.5125.7-83.9145.3000105.1F328F328-I331 HydrophobicContact CD1-CB 4.44Å; F328-I331 HydrophobicContact CD1-CD1 4.48Å; F328-I331 HydrophobicContact CE1-CB 4.14Å; F328-I331 HydrophobicContact CE1-CD1 3.66Å; F328-I331 HydrophobicContact CE1-CG1 4.46Å; F328-I331 HydrophobicContact CZ-CD1 4.4Å
332L26.3Very low30.8Very low176 Ų176137.3 Ų137.392%0.92172%0.723SS**  trans-10581.9153.6-93.2168.3000104.5
333Q28.8Very low29.5Very low163 Ų163140.4 Ų140.476%0.76275%0.745SS**SBendtrans-166.1106.8163.6-110.51641.500108.7
334E26.1Very low28.5Very low186 Ų186145.8 Ų145.887%0.86976%0.758SS**  trans42.296.8144.6-63.2177.2169.800117.6
335T27.2Very low27.3Very low137 Ų137150 Ų15084%0.8478%0.778SS**  trans-146.6108.7137.339.30000109.9
336E23.9Very low26.5Very low195 Ų195154.1 Ų154.191%0.91179%0.793SS**  trans-60129.8162.4-64.4175.3147.800109.7
337L27.3Very low25.8Very low145 Ų145153.1 Ų153.176%0.75980%0.797SS**  trans-143.592.2159.8-104.7152.4000108.6Y339L337-Y339 HydrophobicContact CD2-CD2 3.91Å; L337-Y339 HydrophobicContact CD2-CE2 3.65Å
338S22.4Very low25.8Very low104 Ų104153.2 Ų153.273%0.72780%0.797SS**  trans-74.3120.2167.4157.30000109.3
339Y27.1Very low25.4Very low205 Ų205152.7 Ų152.780%0.80481%0.808SS**  trans-130.3115.5160.4-94.5-85.8000111L337L337-Y339 HydrophobicContact CD2-CD2 3.91Å; L337-Y339 HydrophobicContact CD2-CE2 3.65Å
340H23.2Very low25.5Very low189 Ų189155 Ų15588%0.87582%0.815SS**  trans-77.8125.6162.1-82-24.2000109.3
341G25.8Very low25.7Very low71 Ų71151.3 Ų151.373%0.73281%0.809SS**  trans-153.696.4172.200000111.4V343G341-V343 PolarHBondContact O-N 3.07Å
342K22.7Very low25.6Very low210 Ų210151.7 Ų151.791%0.91381%0.812SS**  trans-60.3127.4161-86.7176.3169.5178.50108.4Q344K342-Q344 PolarHBondContact O-N 2.61Å
343V25.7Very low25.6Very low138 Ų138150.3 Ų150.384%0.83681%0.806SS**  trans-66.9114.9168.4178.80000108G341G341-V343 PolarHBondContact O-N 3.07Å
344Q23.5Very low25.7Very low180 Ų180150.4 Ų150.484%0.84181%0.811SS**  trans-101.2107.3175.9-156.8170.56.400107K342 V346K342-Q344 PolarHBondContact O-N 2.61Å; Q344-V346 PolarHBondContact O-N 2.85Å
345L24.9Very low25.7Very low144 Ų144150.7 Ų150.775%0.75481%0.813SS**  trans-68.9118.2176.7-82.3153000109.7
346V25.4Very low25.7Very low131 Ų131152.6 Ų152.679%0.79481%0.812SS**  trans-97.9104.5166.7177.90000107.1Q344Q344-V346 PolarHBondContact O-N 2.85Å
347S23.8Very low25.9Very low112 Ų112149.9 Ų149.978%0.78380%0.804SS**  trans-85.3121.3168.555.70000109.6
348E27.5Very low25.8Very low178 Ų178152.7 Ų152.783%0.83281%0.813SS**  trans-131102.9158.1-102.4-179.5174.700110
349S24.5Very low26.1Very low108 Ų108153.7 Ų153.776%0.75581%0.806SS**  trans6.3118.8149.752.70000118.8
350L27.2Very low26.1Very low178 Ų178151.5 Ų151.593%0.93281%0.808SS**  trans-131.5120.1139.1-86.8167.9000109.7
351S28.3Very low26.3Very low94 Ų94150 Ų15066%0.65780%0.795SS**  trans-47.5139.1-178.448.20000117.8
352D26.3Very low26.2Very low142 Ų142152.9 Ų152.976%0.75979%0.794SS**  32.5105.9124.6-55.8-18.4000118.2
353N26.8Very low26.6Very low147 Ų147149.8 Ų149.879%0.78678%0.781SS**  167122.9115-81.4-38.7000107.8
354D29.8Very low26.6Very low164 Ų164149.8 Ų149.888%0.87777%0.772SS**  trans157.671.2144.4-74.1-13.8000108.2E356D354-E356 PolarHBondContact O-N 3.46Å
355E26.8Very low26.9Very low193 Ų193146.5 Ų146.590%0.90276%0.759SS**  trans-68.6112149.8-73.6-179159.900106.5
356E27.5Very low27.2Very low176 Ų176144.5 Ų144.582%0.82276%0.757SS**  trans171.5132.3142.2-94.9168.8-170.100110.6D354D354-E356 PolarHBondContact O-N 3.46Å
357N27.1Very low27.4Very low139 Ų139141.6 Ų141.674%0.74374%0.741SS**  trans9961.4169.3-48.8-44.9000117.9E359N357-E359 PolarHBondContact O-N 3.25Å; N357-E359 VanDerWaalsContact O-N 3.08Å
358E26.6Very low28.3Very low203 Ų203140.2 Ų140.295%0.94972%0.722SS**  trans-71.276.7144.3-80.3-170.5151.900109.8
359E26.8Very low28.8Very low125 Ų125138.4 Ų138.458%0.58471%0.714SS**  trans-88.2104.8156.6-80.4-171.515600108.2N357 Y361N357-E359 PolarHBondContact O-N 3.25Å; N357-E359 VanDerWaalsContact O-N 3.08Å; E359-Y361 HydrophobicContact CB-CD2 3.97Å; E359-Y361 HydrophobicContact CB-CE2 3.49Å; E359-Y361 VanDerWaalsContact CB-CE2 3.49Å; E359-Y361 VanDerWaalsContact O-CD2 3.23Å; E359-Y361 WeakPolarHBondContact O-CD2 3.39Å; E359-Y361 PolarHBondContact O-N 2.92Å; E359-Y361 WeakPolarHBondContact OE2-CE2 3.46Å; E359-Y361 VanDerWaalsContact OE2-CZ 3.23Å; E359-Y361 PolarHBondContact OE2-OH 3.5Å
360L27.2Very low29.8Very low159 Ų159141.7 Ų141.783%0.83271%0.714SS**  trans-6081.8171.2-168.182.8000109.8D362L360-D362 VanDerWaalsContact C-N 3.27Å; L360-D362 PolarHBondContact O-N 2.78Å
361Y28.3Very low30.8Very low157 Ų157138 Ų13862%0.61669%0.692SS**  trans-77.982.2169.9-73.3-78.1000109.5E359 F363E359-Y361 HydrophobicContact CB-CD2 3.97Å; E359-Y361 HydrophobicContact CB-CE2 3.49Å; E359-Y361 VanDerWaalsContact CB-CE2 3.49Å; E359-Y361 VanDerWaalsContact O-CD2 3.23Å; E359-Y361 WeakPolarHBondContact O-CD2 3.39Å; E359-Y361 PolarHBondContact O-N 2.92Å; E359-Y361 WeakPolarHBondContact OE2-CE2 3.46Å; E359-Y361 VanDerWaalsContact OE2-CZ 3.23Å; E359-Y361 PolarHBondContact OE2-OH 3.5Å; Y361-F363 VanDerWaalsContact C-N 3.29Å; Y361-F363 PolarHBondContact O-N 2.77Å
362D24.3Very low31.8Very low132 Ų132142.2 Ų142.271%0.70671%0.706SS**  trans-55.496.5158.7-106.2-17.2000107.8L360 E364L360-D362 VanDerWaalsContact C-N 3.27Å; L360-D362 PolarHBondContact O-N 2.78Å; D362-E364 VanDerWaalsContact C-N 3.26Å; D362-E364 PolarHBondContact O-N 3.09Å
363F30.6Very low33.5Very low146 Ų146137.4 Ų137.464%0.6469%0.69SS**  trans-83.389157-125.7-111.8000105.6K258 V263 Y361 I365K258-F363 VanDerWaalsContact NZ-CG 3.33Å; V263-F363 HydrophobicContact CG2-CB 4.4Å; Y361-F363 VanDerWaalsContact C-N 3.29Å; Y361-F363 PolarHBondContact O-N 2.77Å; F363-I365 PolarHBondContact O-N 2.92Å; F363-I365 VanDerWaalsContact O-N 3.14Å
364E25.8Very low35.7Very low138 Ų138131.2 Ų131.265%0.64566%0.658SS**  trans-48.3123161.7-71.4-177.3140.600107.3D362 S366 P367D362-E364 VanDerWaalsContact C-N 3.26Å; D362-E364 PolarHBondContact O-N 3.09Å; E364-S366 VanDerWaalsContact C-N 3.28Å; E364-S366 PolarHBondContact O-N 2.84Å; E364-P367 HydrophobicContact CB-CG 4.38Å
365I30.2Very low38.1Very low110 Ų110125.8 Ų125.856%0.56463%0.632SS**  trans-48.3107.7155.3-65.6163.3000103.5V263 F363 P367V263-I365 HydrophobicContact CG1-CG1 3.82Å; F363-I365 PolarHBondContact O-N 2.92Å; F363-I365 VanDerWaalsContact O-N 3.14Å; I365-P367 VanDerWaalsContact C-N 3.32Å; I365-P367 WeakPolarHBondContact O-CA 3.35Å; I365-P367 WeakPolarHBondContact O-CD 3.31Å
366S30Very low40.8Very low103 Ų103124.8 Ų124.872%0.7262%0.622SS**  trans-38.2100-169.254.70000108.1E364 E368E364-S366 VanDerWaalsContact C-N 3.28Å; E364-S366 PolarHBondContact O-N 2.84Å; S366-E368 PolarHBondContact O-N 2.83Å
367P30.4Very low43.6Very low70 Ų70122.5 Ų122.546%0.45561%0.609SS.*  trans-70.1113.9-171.923.2-23.8000100.5E364 I365 E369E364-P367 HydrophobicContact CB-CG 4.38Å; I365-P367 VanDerWaalsContact C-N 3.32Å; I365-P367 WeakPolarHBondContact O-CA 3.35Å; I365-P367 WeakPolarHBondContact O-CD 3.31Å; P367-E369 WeakPolarHBondContact O-CA 3.32Å; P367-E369 PolarHBondContact O-N 3.24Å
368E42.3Very low46.5Very low82 Ų82116.3 Ų116.338%0.38358%0.576SS.*  trans-31.5106.4-175.8-83-172.9170.800107.4S366 K370 N507 Y511S366-E368 PolarHBondContact O-N 2.83Å; E368-K370 VanDerWaalsContact C-N 3.26Å; E368-K370 PolarHBondContact O-N 2.97Å; E368-N507 PolarHBondContact OE1-ND2 3.38Å; E368-Y511 VanDerWaalsContact CD-OH 3.25Å; E368-Y511 PolarHBondContact OE1-OH 2.71Å; E368-Y511 PolarHBondContact OE2-OH 3.1Å; E368-Y511 VanDerWaalsContact OE2-OH 3.14Å
369E38.3Very low49.2Very low141 Ų141109.2 Ų109.266%0.65954%0.541SS*.  trans-55.3104.7-168.9-88.9-172.717300104.6P367 H371 R615P367-E369 WeakPolarHBondContact O-CA 3.32Å; P367-E369 PolarHBondContact O-N 3.24Å; E369-H371 PolarHBondContact O-N 3.27Å; E369-H371 IonicContact OE2-CE1 2.8Å; E369-H371 PolarHBondContact OE2-CE1 3.31Å; E369-H371 VanDerWaalsContact OE2-CE1 3.3Å; E369-R615 PolarHBondContact O-NH2 2.92Å
370K44.4Very low52Low176 Ų176108.3 Ų108.377%0.76554%0.54SS*.  trans-7486.1179.1-83.2-177-179.7172.30102E368 L372E368-K370 VanDerWaalsContact C-N 3.26Å; E368-K370 PolarHBondContact O-N 2.97Å; K370-L372 PolarHBondContact O-N 3.24Å
371H49.1Very low54.9Low102 Ų102102.8 Ų102.847%0.47251%0.513SS..  trans-51.4110.6168.1-69.6-47.2000105.6E369 G373E369-H371 PolarHBondContact O-N 3.27Å; E369-H371 IonicContact OE2-CE1 2.8Å; E369-H371 PolarHBondContact OE2-CE1 3.31Å; E369-H371 VanDerWaalsContact OE2-CE1 3.3Å; H371-G373 PolarHBondContact O-N 3.14Å
372L49.3Very low57.6Low181 Ų18195.3 Ų95.395%0.94848%0.484SS*.SBendtrans-67.299.7179.1-100.495000106.9K370K370-L372 PolarHBondContact O-N 3.24Å
373G62.2Low60.4Low41 Ų4190.7 Ų90.742%0.42346%0.459SS..SBendtrans100.1140.517800000113.5H371H371-G373 PolarHBondContact O-N 3.14Å
374V73.3Confident63.2Low18 Ų1893.1 Ų93.111%0.10946%0.463CS..  trans-83.9133.8178.7177.90000110.3T378 Y379 M610 V611V374-T378 HydrophobicContact CG1-CG2 3.69Å; V374-Y379 HydrophobicContact CB-CE2 3.99Å; V374-Y379 HydrophobicContact CG1-CD2 4.22Å; V374-Y379 HydrophobicContact CG1-CE2 3.71Å; V374-M610 HydrophobicContact CB-CB 4.38Å; V374-M610 HydrophobicContact CG1-CB 4.07Å; V374-M610 HydrophobicContact CG2-CB 3.9Å; V374-V611 HydrophobicContact CG2-CB 4.4Å; V374-V611 HydrophobicContact CG2-CG2 3.66Å
375S80.3Confident66.1Low49 Ų4988.1 Ų88.134%0.34344%0.44SS..  trans-62.5138.7176.1-170.90000112.3K377 T378 E614S375-K377 PolarHBondContact O-N 3.43Å; S375-T378 WeakPolarHBondContact O-CB 3.27Å; S375-T378 PolarHBondContact O-N 3.11Å; S375-T378 PolarHBondContact O-OG1 2.93Å; S375-E614 PolarHBondContact N-OE1 3.48Å
376Y82.4Confident68.7Low172 Ų17283.2 Ų83.268%0.67542%0.415SS*.Hα-helixtrans-56.9-26174.377.8-94.1000112.7T378 Y379 L380Y376-T378 PolarHBondContact O-N 2.87Å; Y376-Y379 PolarHBondContact O-N 2.89Å; Y376-L380 PolarHBondContact O-N 2.84Å
377K87.3Confident71.3Confident129 Ų12979.4 Ų79.456%0.56139%0.392SS*.Hα-helixtrans-62.2-32.3175.4-69.3177.7178.2173.70112S375 L380 T381S375-K377 PolarHBondContact O-N 3.43Å; K377-L380 PolarHBondContact O-N 2.86Å; K377-T381 WeakPolarHBondContact O-CB 3.36Å; K377-T381 PolarHBondContact O-N 2.7Å; K377-T381 PolarHBondContact O-OG1 3.05Å
378T86.7Confident73.8Confident9 Ų982.2 Ų82.26%0.05540%0.399CS..Hα-helixtrans-63.7-47.1178.3-59.20000110.4V374 S375 Y376 L380 T381 Y382 V613 E614 I617V374-T378 HydrophobicContact CG1-CG2 3.69Å; S375-T378 WeakPolarHBondContact O-CB 3.27Å; S375-T378 PolarHBondContact O-N 3.11Å; S375-T378 PolarHBondContact O-OG1 2.93Å; Y376-T378 PolarHBondContact O-N 2.87Å; T378-L380 PolarHBondContact O-N 3.04Å; T378-T381 PolarHBondContact O-N 3.06Å; T378-Y382 PolarHBondContact O-N 2.94Å; T378-V613 HydrophobicContact CG2-CB 4.46Å; T378-V613 HydrophobicContact CG2-CG1 4.25Å; T378-E614 HydrophobicContact CG2-CB 3.83Å; T378-E614 HydrophobicContact CG2-CG 4.34Å; T378-E614 PolarHBondContact OG1-OE1 2.99Å; T378-I617 HydrophobicContact CG2-CD1 4.06Å
379Y84.1Confident75.8Confident53 Ų5382.1 Ų82.121%0.20841%0.405CS..Hα-helixtrans-59.5-46.1175.1-66.5-91.9000112.5V374 Y376 T381 Y382 L383 W522 V606 M610V374-Y379 HydrophobicContact CB-CE2 3.99Å; V374-Y379 HydrophobicContact CG1-CD2 4.22Å; V374-Y379 HydrophobicContact CG1-CE2 3.71Å; Y376-Y379 PolarHBondContact O-N 2.89Å; Y379-T381 VanDerWaalsContact C-N 3.33Å; Y379-T381 PolarHBondContact O-N 2.84Å; Y379-Y382 PolarHBondContact O-N 2.99Å; Y379-L383 WeakPolarHBondContact O-CG 3.28Å; Y379-L383 PolarHBondContact O-N 2.78Å; Y379-W522 AromaticContact CD1-CH2 3.81Å; Y379-W522 HydrophobicContact CD1-CH2 3.81Å; Y379-W522 AromaticContact CD1-CZ3 3.96Å; Y379-W522 HydrophobicContact CD1-CZ3 3.96Å; Y379-W522 HydrophobicContact CE1-CH2 4.29Å; Y379-W522 HydrophobicContact CE1-CZ3 4.08Å; Y379-V606 HydrophobicContact CE1-CG1 4.22Å; Y379-M610 HydrophobicContact CD1-CG 4.09Å; Y379-M610 HydrophobicContact CD1-SD 3.85Å; Y379-M610 HydrophobicContact CE1-CB 4.35Å; Y379-M610 HydrophobicContact CE1-CG 3.49Å; Y379-M610 VanDerWaalsContact CE1-CG 3.49Å; Y379-M610 HydrophobicContact CE1-SD 3.91Å; Y379-M610 HydrophobicContact CG-SD 4.39Å
380L85.7Confident78.1Confident106 Ų10679.2 Ų79.256%0.55540%0.4SS*.Hα-helixtrans-63.9-39.9179.3-174.365.4000111.7Y376 K377 T378 L383 R384Y376-L380 PolarHBondContact O-N 2.84Å; K377-L380 PolarHBondContact O-N 2.86Å; T378-L380 PolarHBondContact O-N 3.04Å; L380-L383 PolarHBondContact O-N 2.7Å; L380-R384 WeakPolarHBondContact O-CB 3.37Å; L380-R384 PolarHBondContact O-N 2.64Å
381T86.9Confident80Confident44 Ų4473.6 Ų73.627%0.2738%0.38SS..Hα-helixtrans-64.2-45.6177.2-56.10000110.7K377 T378 Y379 L383 R384 E385 I617K377-T381 WeakPolarHBondContact O-CB 3.36Å; K377-T381 PolarHBondContact O-N 2.7Å; K377-T381 PolarHBondContact O-OG1 3.05Å; T378-T381 PolarHBondContact O-N 3.06Å; Y379-T381 VanDerWaalsContact C-N 3.33Å; Y379-T381 PolarHBondContact O-N 2.84Å; T381-L383 VanDerWaalsContact C-N 3.31Å; T381-L383 PolarHBondContact O-N 2.9Å; T381-R384 PolarHBondContact O-N 3.05Å; T381-R384 VanDerWaalsContact O-N 3.15Å; T381-E385 WeakPolarHBondContact O-CG 3.5Å; T381-E385 PolarHBondContact O-N 3.4Å; T381-E385 VanDerWaalsContact O-N 3.13Å; T381-I617 HydrophobicContact CG2-CD1 3.76Å; T381-I617 HydrophobicContact CG2-CG1 4.26Å; T381-I617 HydrophobicContact CG2-CG2 4.49Å
382Y86.2Confident81.6Confident0 Ų070.6 Ų70.60%037%0.367CS..Hα-helixtrans-57.8-41.7175.8-178.9-101.5000112.7T378 Y379 L477 S480 L484 L515 L518 W522 M610 V613T378-Y382 PolarHBondContact O-N 2.94Å; Y379-Y382 PolarHBondContact O-N 2.99Å; Y382-L477 HydrophobicContact CE1-CD2 3.78Å; Y382-S480 PolarHBondContact O-OG 2.97Å; Y382-L484 HydrophobicContact CD2-CD1 3.41Å; Y382-L484 VanDerWaalsContact CD2-CD1 3.41Å; Y382-L484 HydrophobicContact CE2-CD1 3.89Å; Y382-L484 HydrophobicContact CG-CD1 4.46Å; Y382-L515 HydrophobicContact CE2-CD1 4.09Å; Y382-L518 HydrophobicContact CD2-CD2 4.34Å; Y382-L518 HydrophobicContact CE1-CD2 4.39Å; Y382-L518 HydrophobicContact CE2-CD2 3.72Å; Y382-W522 HydrophobicContact CE1-CD2 4.49Å; Y382-M610 HydrophobicContact CD1-CE 4.2Å; Y382-M610 HydrophobicContact CD2-CE 4.49Å; Y382-M610 HydrophobicContact CE1-CE 4.44Å; Y382-M610 HydrophobicContact CG-CE 4.24Å; Y382-V613 HydrophobicContact CD2-CG1 3.92Å; Y382-V613 HydrophobicContact CD2-CG2 4.41Å; Y382-V613 HydrophobicContact CG-CG1 4.45Å
383L83.9Confident83.3Confident35 Ų3566.5 Ų66.518%0.18335%0.35CS..Hα-helixtrans-71.6-34.4176.4-68.5175.8000112.8Y379 L380 T381 E385 I386 L392 W522Y379-L383 WeakPolarHBondContact O-CG 3.28Å; Y379-L383 PolarHBondContact O-N 2.78Å; L380-L383 PolarHBondContact O-N 2.7Å; T381-L383 VanDerWaalsContact C-N 3.31Å; T381-L383 PolarHBondContact O-N 2.9Å; L383-E385 VanDerWaalsContact C-N 3.28Å; L383-E385 PolarHBondContact O-N 2.91Å; L383-I386 HydrophobicContact CD2-CD1 3.92Å; L383-I386 VanDerWaalsContact O-CB 3.26Å; L383-I386 WeakPolarHBondContact O-CB 3.37Å; L383-I386 WeakPolarHBondContact O-CG1 3.2Å; L383-I386 PolarHBondContact O-N 3.1Å; L383-L392 HydrophobicContact CB-CD1 4.4Å; L383-L392 HydrophobicContact CB-CD2 4.24Å; L383-L392 HydrophobicContact CD1-CD1 4.32Å; L383-L392 HydrophobicContact CD1-CD2 4.4Å; L383-L392 HydrophobicContact CD2-CD1 4.12Å; L383-W522 HydrophobicContact CD2-CZ2 4.25Å
384R87.8Confident84.4Confident196 Ų19668.1 Ų68.174%0.7435%0.354SS*.Hα-helixtrans-66.3-29.9177.4-168.7174.3-177.1168.50.7112.4L380 T381 I386 G387L380-R384 WeakPolarHBondContact O-CB 3.37Å; L380-R384 PolarHBondContact O-N 2.64Å; T381-R384 PolarHBondContact O-N 3.05Å; T381-R384 VanDerWaalsContact O-N 3.15Å; R384-I386 PolarHBondContact O-N 3.19Å; R384-G387 PolarHBondContact O-N 3.21Å; R384-G387 VanDerWaalsContact O-O 3.12Å
385E87.3Confident84.9Confident33 Ų3367.8 Ų67.815%0.15435%0.351CS..THydrogen-bonded Turntrans-68.8-15.2176.9-69.4-70.4170.100113.3T381 L383 G387 S480 R483 L484 R487T381-E385 WeakPolarHBondContact O-CG 3.5Å; T381-E385 PolarHBondContact O-N 3.4Å; T381-E385 VanDerWaalsContact O-N 3.13Å; L383-E385 VanDerWaalsContact C-N 3.28Å; L383-E385 PolarHBondContact O-N 2.91Å; E385-G387 PolarHBondContact O-N 3.26Å; E385-S480 WeakPolarHBondContact CB-OG 3.25Å; E385-R483 WeakPolarHBondContact O-CD 3.2Å; E385-R483 PolarHBondContact O-NH1 3.29Å; E385-L484 HydrophobicContact CB-CG 4.27Å; E385-L484 HydrophobicContact CG-CD1 4.49Å; E385-L484 HydrophobicContact CG-CD2 3.83Å; E385-L484 HydrophobicContact CG-CG 3.91Å; E385-R487 IonicContact OE1-NH1 2.77Å; E385-R487 PolarHBondContact OE1-NH1 3.47Å; E385-R487 VanDerWaalsContact OE1-NH1 3.13Å
386I84.8Confident84.9Confident7 Ų769 Ų694%0.03635%0.353CS..THydrogen-bonded Turntrans-58.6-39171.8-64.8174.1000110.7L383 R384 V391 R483L383-I386 HydrophobicContact CD2-CD1 3.92Å; L383-I386 VanDerWaalsContact O-CB 3.26Å; L383-I386 WeakPolarHBondContact O-CB 3.37Å; L383-I386 WeakPolarHBondContact O-CG1 3.2Å; L383-I386 PolarHBondContact O-N 3.1Å; R384-I386 PolarHBondContact O-N 3.19Å; I386-V391 HydrophobicContact CG2-CG1 3.99Å; I386-R483 PolarHBondContact O-NH1 3.03Å
387G83.8Confident84.9Confident23 Ų2363.2 Ų63.224%0.23734%0.338CS..SBendtrans148.6-146.9-179.200000112.4R384 E385R384-G387 PolarHBondContact O-N 3.21Å; R384-G387 VanDerWaalsContact O-O 3.12Å; E385-G387 PolarHBondContact O-N 3.26Å
388H84.7Confident84.7Confident129 Ų12958.2 Ų58.260%0.59732%0.317SS*.SBendtrans-62.1141-179.8-163.2-94.2000110.8C390 V391H388-C390 PolarHBondContact CE1-SG 2.94Å; H388-C390 PolarHBondContact ND1-N 3.06Å; H388-C390 PolarHBondContact ND1-SG 3.19Å; H388-C390 PolarHBondContact O-N 2.82Å; H388-V391 WeakPolarHBondContact O-CB 2.94Å; H388-V391 PolarHBondContact O-N 3Å
389P84Confident84.4Confident81 Ų8158.2 Ų58.253%0.52632%0.318SS..Hα-helixtrans-51-30.3178.6-29.635.3000114.6V391 L392 V393P389-V391 PolarHBondContact O-N 2.95Å; P389-L392 WeakPolarHBondContact O-CB 3.45Å; P389-L392 PolarHBondContact O-N 3.4Å; P389-V393 PolarHBondContact O-N 3.2Å
390C85.1Confident84.1Confident80 Ų8059.9 Ų59.954%0.54133%0.33SS..Hα-helixtrans-56.5-33.4174.1-62.80000113.4H388 V393 C394H388-C390 PolarHBondContact CE1-SG 2.94Å; H388-C390 PolarHBondContact ND1-N 3.06Å; H388-C390 PolarHBondContact ND1-SG 3.19Å; H388-C390 PolarHBondContact O-N 2.82Å; C390-V393 PolarHBondContact O-N 2.93Å; C390-C394 VanDerWaalsContact O-CB 3.24Å; C390-C394 WeakPolarHBondContact O-CB 3.35Å; C390-C394 PolarHBondContact O-N 2.99Å
391V85.2Confident83.9Confident57 Ų5760.7 Ų60.735%0.34533%0.334SS..Hα-helixtrans-66.7-41.2176.8-179.20000110.3I386 H388 P389 C394 L395I386-V391 HydrophobicContact CG2-CG1 3.99Å; H388-V391 WeakPolarHBondContact O-CB 2.94Å; H388-V391 PolarHBondContact O-N 3Å; P389-V391 PolarHBondContact O-N 2.95Å; V391-C394 PolarHBondContact O-N 2.83Å; V391-L395 HydrophobicContact CG1-CD1 4.25Å; V391-L395 WeakPolarHBondContact O-CB 3.39Å; V391-L395 VanDerWaalsContact O-CG 3.3Å; V391-L395 WeakPolarHBondContact O-CG 3.36Å; V391-L395 PolarHBondContact O-N 2.9Å
392L82Confident83.7Confident40 Ų4058.8 Ų58.821%0.20932%0.323CS..Hα-helixtrans-65.2-44.2176.5-177.165.2000111.2L383 P389 C394 L395 L396L383-L392 HydrophobicContact CB-CD1 4.4Å; L383-L392 HydrophobicContact CB-CD2 4.24Å; L383-L392 HydrophobicContact CD1-CD1 4.32Å; L383-L392 HydrophobicContact CD1-CD2 4.4Å; L383-L392 HydrophobicContact CD2-CD1 4.12Å; P389-L392 WeakPolarHBondContact O-CB 3.45Å; P389-L392 PolarHBondContact O-N 3.4Å; L392-C394 VanDerWaalsContact C-N 3.31Å; L392-C394 PolarHBondContact O-N 3.28Å; L392-L395 PolarHBondContact O-N 3.46Å; L392-L396 HydrophobicContact CG-CD1 4.23Å; L392-L396 WeakPolarHBondContact O-CB 3.43Å; L392-L396 VanDerWaalsContact O-CG 3.31Å; L392-L396 WeakPolarHBondContact O-CG 3.43Å; L392-L396 PolarHBondContact O-N 3.22Å
393V85.3Confident83.4Confident95 Ų9560.2 Ų60.258%0.57633%0.329SS*.Hα-helixtrans-60.6-42.5175.3176.40000110.8P389 C390 L396 S397P389-V393 PolarHBondContact O-N 3.2Å; C390-V393 PolarHBondContact O-N 2.93Å; V393-L396 PolarHBondContact O-N 2.93Å; V393-S397 WeakPolarHBondContact O-CB 3.32Å; V393-S397 PolarHBondContact O-N 3.28Å; V393-S397 PolarHBondContact O-OG 2.72Å
394C85.8Confident83.1Confident75 Ų7560.5 Ų60.551%0.50734%0.341SS..Hα-helixtrans-64.1-42.5176.3-177.30000112.4C390 V391 L392 L396 S397 M398C390-C394 VanDerWaalsContact O-CB 3.24Å; C390-C394 WeakPolarHBondContact O-CB 3.35Å; C390-C394 PolarHBondContact O-N 2.99Å; V391-C394 PolarHBondContact O-N 2.83Å; L392-C394 VanDerWaalsContact C-N 3.31Å; L392-C394 PolarHBondContact O-N 3.28Å; C394-L396 VanDerWaalsContact C-N 3.33Å; C394-L396 PolarHBondContact O-N 3.01Å; C394-S397 WeakPolarHBondContact CA-OG 3.13Å; C394-S397 PolarHBondContact O-N 3.43Å; C394-S397 PolarHBondContact O-OG 3.37Å; C394-M398 VanDerWaalsContact O-CB 3.26Å; C394-M398 WeakPolarHBondContact O-CB 3.23Å; C394-M398 PolarHBondContact O-N 3.07Å
395L82.7Confident82.9Confident10 Ų1054 Ų545%0.05232%0.318CS..Hα-helixtrans-62.4-41.3175.2-77171.9000111.9V391 L392 A399 I472 L473V391-L395 HydrophobicContact CG1-CD1 4.25Å; V391-L395 WeakPolarHBondContact O-CB 3.39Å; V391-L395 VanDerWaalsContact O-CG 3.3Å; V391-L395 WeakPolarHBondContact O-CG 3.36Å; V391-L395 PolarHBondContact O-N 2.9Å; L392-L395 PolarHBondContact O-N 3.46Å; L395-A399 WeakPolarHBondContact O-CB 3.47Å; L395-A399 PolarHBondContact O-N 3.04Å; L395-A399 VanDerWaalsContact O-N 3.07Å; L395-I472 HydrophobicContact CD2-CB 4.21Å; L395-I472 HydrophobicContact CD2-CG2 3.61Å; L395-L473 HydrophobicContact CD1-CD1 4.42Å; L395-L473 HydrophobicContact CD2-CB 4.26Å; L395-L473 HydrophobicContact CD2-CD1 4.5Å
396L80.6Confident82.6Confident74 Ų7453.4 Ų53.439%0.38732%0.315SS..Hα-helixtrans-70-39.7177.1-70.9172.8000112.1L392 V393 C394 A399 L400L392-L396 HydrophobicContact CG-CD1 4.23Å; L392-L396 WeakPolarHBondContact O-CB 3.43Å; L392-L396 VanDerWaalsContact O-CG 3.31Å; L392-L396 WeakPolarHBondContact O-CG 3.43Å; L392-L396 PolarHBondContact O-N 3.22Å; V393-L396 PolarHBondContact O-N 2.93Å; C394-L396 VanDerWaalsContact C-N 3.33Å; C394-L396 PolarHBondContact O-N 3.01Å; L396-A399 WeakPolarHBondContact O-CB 3.46Å; L396-A399 PolarHBondContact O-N 3.14Å; L396-L400 WeakPolarHBondContact O-CG 3.39Å; L396-L400 PolarHBondContact O-N 3.07Å
397S82.2Confident82.3Confident52 Ų5255.7 Ų55.736%0.36433%0.329SS..Hα-helixtrans-68.7-43.6177.468.50000111.4V393 C394 A399 L400 L401V393-S397 WeakPolarHBondContact O-CB 3.32Å; V393-S397 PolarHBondContact O-N 3.28Å; V393-S397 PolarHBondContact O-OG 2.72Å; C394-S397 WeakPolarHBondContact CA-OG 3.13Å; C394-S397 PolarHBondContact O-N 3.43Å; C394-S397 PolarHBondContact O-OG 3.37Å; S397-A399 PolarHBondContact O-N 3.03Å; S397-L400 PolarHBondContact O-N 3.2Å; S397-L400 VanDerWaalsContact O-N 3.13Å; S397-L401 WeakPolarHBondContact O-CG 3.34Å; S397-L401 PolarHBondContact O-N 3.21Å
398M84Confident82.2Confident23 Ų2358.6 Ų58.611%0.11334%0.335CS..Hα-helixtrans-60.3-37.1174.3-166.5-176.6-172.600111.5C394 L401 V402 V465 L468 Q469 I472C394-M398 VanDerWaalsContact O-CB 3.26Å; C394-M398 WeakPolarHBondContact O-CB 3.23Å; C394-M398 PolarHBondContact O-N 3.07Å; M398-L401 PolarHBondContact O-N 3.36Å; M398-V402 WeakPolarHBondContact O-CG2 3.37Å; M398-V402 PolarHBondContact O-N 2.8Å; M398-V465 HydrophobicContact CE-CG1 3.98Å; M398-V465 WeakPolarHBondContact CE-O 3.43Å; M398-L468 HydrophobicContact CE-CB 3.91Å; M398-L468 HydrophobicContact CE-CD2 3.88Å; M398-L468 HydrophobicContact CE-CG 3.79Å; M398-Q469 HydrophobicContact CB-CG 4.38Å; M398-Q469 VanDerWaalsContact CE-CA 3.5Å; M398-Q469 HydrophobicContact CE-CB 3.65Å; M398-Q469 HydrophobicContact CE-CG 4.4Å; M398-Q469 VanDerWaalsContact CE-N 3.29Å; M398-Q469 HydrophobicContact CG-CB 4.1Å; M398-Q469 HydrophobicContact CG-CG 3.9Å; M398-Q469 VanDerWaalsContact SD-CA 3.57Å; M398-Q469 HydrophobicContact SD-CB 3.69Å; M398-Q469 HydrophobicContact SD-CG 3.79Å; M398-I472 HydrophobicContact CE-CD1 4.32Å; M398-I472 HydrophobicContact SD-CD1 3.98Å
399A79.6Confident82.1Confident9 Ų952.5 Ų52.57%0.07431%0.307CS..Hα-helixtrans-63.4-43.3173.700000113.5L395 L396 S397 Q403 R530L395-A399 WeakPolarHBondContact O-CB 3.47Å; L395-A399 PolarHBondContact O-N 3.04Å; L395-A399 VanDerWaalsContact O-N 3.07Å; L396-A399 WeakPolarHBondContact O-CB 3.46Å; L396-A399 PolarHBondContact O-N 3.14Å; S397-A399 PolarHBondContact O-N 3.03Å; A399-Q403 WeakPolarHBondContact O-CB 3.47Å; A399-Q403 PolarHBondContact O-N 3.07Å; A399-Q403 VanDerWaalsContact O-N 3.12Å; A399-R530 HydrophobicContact CB-CG 4.17Å
400L78.1Confident81.7Confident89 Ų8949.7 Ų49.747%0.46629%0.287SS..Hα-helixtrans-65.1-40.9175.9-72.2172.1000111.3L396 S397 Q403 G404 K533L396-L400 WeakPolarHBondContact O-CG 3.39Å; L396-L400 PolarHBondContact O-N 3.07Å; S397-L400 PolarHBondContact O-N 3.2Å; S397-L400 VanDerWaalsContact O-N 3.13Å; L400-Q403 PolarHBondContact O-N 3.24Å; L400-G404 PolarHBondContact O-N 3.17Å; L400-K533 HydrophobicContact CD2-CD 3.68Å
401L82.8Confident81.4Confident122 Ų12250.6 Ų50.664%0.63928%0.28SS*.Hα-helixtrans-62.6-47.8177.7-72.1171.4000112S397 M398 Q403 G404 F405S397-L401 WeakPolarHBondContact O-CG 3.34Å; S397-L401 PolarHBondContact O-N 3.21Å; M398-L401 PolarHBondContact O-N 3.36Å; L401-Q403 VanDerWaalsContact C-N 3.3Å; L401-Q403 PolarHBondContact O-N 3.04Å; L401-G404 PolarHBondContact O-N 3.06Å; L401-F405 WeakPolarHBondContact O-CB 3.3Å; L401-F405 PolarHBondContact O-N 2.9Å
402V82.6Confident81.2Confident5 Ų548.5 Ų48.53%0.0327%0.265CS..Hα-helixtrans-60.2-42176.5171.20000111.1M398 Y406 L462 V465 Q469M398-V402 WeakPolarHBondContact O-CG2 3.37Å; M398-V402 PolarHBondContact O-N 2.8Å; V402-Y406 VanDerWaalsContact O-CB 3.31Å; V402-Y406 WeakPolarHBondContact O-CB 3.38Å; V402-Y406 PolarHBondContact O-N 3.38Å; V402-L462 HydrophobicContact CG1-CD1 4.07Å; V402-V465 HydrophobicContact CG2-CB 4.14Å; V402-V465 HydrophobicContact CG2-CG1 3.39Å; V402-Q469 HydrophobicContact CG2-CB 4.37Å
403Q79.2Confident80.9Confident29 Ų2947.6 Ų47.614%0.13626%0.261CS..Hα-helixtrans-68.1-42.2178.7-175.856.249.200112.2A399 L400 L401 F405 Y406 T407 R534A399-Q403 WeakPolarHBondContact O-CB 3.47Å; A399-Q403 PolarHBondContact O-N 3.07Å; A399-Q403 VanDerWaalsContact O-N 3.12Å; L400-Q403 PolarHBondContact O-N 3.24Å; L401-Q403 VanDerWaalsContact C-N 3.3Å; L401-Q403 PolarHBondContact O-N 3.04Å; Q403-F405 VanDerWaalsContact C-N 3.35Å; Q403-Y406 WeakPolarHBondContact O-CB 3.33Å; Q403-Y406 PolarHBondContact O-N 3.35Å; Q403-T407 PolarHBondContact NE2-OG1 3.42Å; Q403-T407 PolarHBondContact O-N 3.09Å; Q403-T407 PolarHBondContact O-OG1 3.47Å; Q403-T407 VanDerWaalsContact O-OG1 3.1Å; Q403-R534 VanDerWaalsContact NE2-NH2 3.1Å
404G77Confident80.3Confident42 Ų4243.1 Ų43.143%0.43323%0.234SC..Hα-helixtrans-61.3-45175.700000111.4L400 L401 Y406 T407 F408L400-G404 PolarHBondContact O-N 3.17Å; L401-G404 PolarHBondContact O-N 3.06Å; G404-Y406 PolarHBondContact O-N 2.83Å; G404-T407 PolarHBondContact O-N 3.2Å; G404-F408 WeakPolarHBondContact O-CB 3.38Å; G404-F408 PolarHBondContact O-N 2.92Å
405F83.6Confident79.5Confident58 Ų5840.6 Ų40.625%0.25422%0.215SC..Hα-helixtrans-66.5-37.9178-162.2-120000112.6L401 Q403 F408 C409 M458 T461 L462L401-F405 WeakPolarHBondContact O-CB 3.3Å; L401-F405 PolarHBondContact O-N 2.9Å; Q403-F405 VanDerWaalsContact C-N 3.35Å; F405-F408 PolarHBondContact O-N 2.75Å; F405-C409 PolarHBondContact O-N 2.99Å; F405-C409 PolarHBondContact O-SG 3.42Å; F405-M458 HydrophobicContact CE1-CB 4.47Å; F405-M458 WeakPolarHBondContact CE1-O 3.4Å; F405-M458 HydrophobicContact CZ-CB 3.99Å; F405-M458 HydrophobicContact CZ-CG 4.16Å; F405-T461 HydrophobicContact CE1-CG2 3.85Å; F405-T461 HydrophobicContact CZ-CG2 3.99Å; F405-L462 HydrophobicContact CB-CD1 4.34Å; F405-L462 HydrophobicContact CD1-CB 3.69Å; F405-L462 HydrophobicContact CD1-CD1 3.8Å; F405-L462 HydrophobicContact CD1-CG 4.28Å; F405-L462 HydrophobicContact CE1-CB 3.82Å
406Y81.1Confident78.8Confident22 Ų2241.3 Ų41.39%0.08622%0.218CC..Hα-helixtrans-58.4-50.2171.4178.7-75.1000111.6Y65 R69 V402 Q403 G404 F408 C409 D410 L462Y65-Y406 AromaticContact CD1-CD2 3.88Å; Y65-Y406 HydrophobicContact CD1-CD2 3.88Å; Y65-Y406 AromaticContact CD1-CE2 3.97Å; Y65-Y406 HydrophobicContact CD1-CE2 3.97Å; Y65-Y406 WeakPolarHBondContact O-CE2 3.28Å; R69-Y406 VanDerWaalsContact CZ-CE2 3.45Å; R69-Y406 VanDerWaalsContact NH2-CD2 3.27Å; R69-Y406 VanDerWaalsContact NH2-CG 3.26Å; R69-Y406 PolarHBondContact NH2-O 2.81Å; V402-Y406 VanDerWaalsContact O-CB 3.31Å; V402-Y406 WeakPolarHBondContact O-CB 3.38Å; V402-Y406 PolarHBondContact O-N 3.38Å; Q403-Y406 WeakPolarHBondContact O-CB 3.33Å; Q403-Y406 PolarHBondContact O-N 3.35Å; G404-Y406 PolarHBondContact O-N 2.83Å; Y406-F408 VanDerWaalsContact C-N 3.31Å; Y406-F408 PolarHBondContact O-N 3.45Å; Y406-C409 WeakPolarHBondContact O-CB 3.39Å; Y406-C409 PolarHBondContact O-N 3.18Å; Y406-D410 VanDerWaalsContact CE1-OD2 3.27Å; Y406-D410 WeakPolarHBondContact CE1-OD2 3.49Å; Y406-D410 PolarHBondContact O-N 3.47Å; Y406-L462 HydrophobicContact CD2-CD2 4.14Å
407T78.3Confident78.1Confident55 Ų5538.5 Ų38.534%0.33720%0.203SC..Hα-helixtrans-65.5-38-179.9-560000111.1Q403 G404 C409 D410 W411Q403-T407 PolarHBondContact NE2-OG1 3.42Å; Q403-T407 PolarHBondContact O-N 3.09Å; Q403-T407 PolarHBondContact O-OG1 3.47Å; Q403-T407 VanDerWaalsContact O-OG1 3.1Å; G404-T407 PolarHBondContact O-N 3.2Å; T407-C409 VanDerWaalsContact C-N 3.3Å; T407-C409 PolarHBondContact O-N 3.19Å; T407-D410 PolarHBondContact O-N 3.48Å; T407-D410 VanDerWaalsContact O-N 3.12Å; T407-W411 PolarHBondContact O-N 3.39Å
408F82.5Confident77.3Confident84 Ų8436.9 Ų36.937%0.36819%0.191SC..Hα-helixtrans-62.4-36.4176.3-175.1-110.7000112.2G404 F405 Y406 D410 W411 W412 M458G404-F408 WeakPolarHBondContact O-CB 3.38Å; G404-F408 PolarHBondContact O-N 2.92Å; F405-F408 PolarHBondContact O-N 2.75Å; Y406-F408 VanDerWaalsContact C-N 3.31Å; Y406-F408 PolarHBondContact O-N 3.45Å; F408-D410 VanDerWaalsContact C-N 3.31Å; F408-D410 PolarHBondContact O-N 3.07Å; F408-W411 AromaticContact CD2-CE3 3.91Å; F408-W411 HydrophobicContact CD2-CE3 3.91Å; F408-W411 HydrophobicContact CD2-CZ3 4.3Å; F408-W411 AromaticContact CE2-CE3 3.68Å; F408-W411 HydrophobicContact CE2-CE3 3.68Å; F408-W411 AromaticContact CE2-CZ3 3.63Å; F408-W411 HydrophobicContact CE2-CZ3 3.63Å; F408-W411 HydrophobicContact CZ-CZ3 4.38Å; F408-W411 PolarHBondContact O-N 3.26Å; F408-W412 HydrophobicContact CE1-CE3 4.12Å; F408-W412 AromaticContact CZ-CE3 3.77Å; F408-W412 HydrophobicContact CZ-CE3 3.77Å; F408-W412 HydrophobicContact CZ-CZ3 4.13Å; F408-W412 WeakPolarHBondContact O-CB 3.47Å; F408-W412 PolarHBondContact O-N 2.91Å; F408-M458 HydrophobicContact CD1-CE 3.28Å; F408-M458 HydrophobicContact CE1-CE 3.46Å; F408-M458 VanDerWaalsContact CE1-CE 3.46Å; F408-M458 HydrophobicContact CE1-SD 4.24Å; F408-M458 HydrophobicContact CG-CE 4.33Å
409C82.1Confident76.3Confident0 Ų036.9 Ų36.90%019%0.191CC..Hα-helixtrans-61.8-35.9172.9-65.60000113.2F405 Y406 T407 L413 W455 M458F405-C409 PolarHBondContact O-N 2.99Å; F405-C409 PolarHBondContact O-SG 3.42Å; Y406-C409 WeakPolarHBondContact O-CB 3.39Å; Y406-C409 PolarHBondContact O-N 3.18Å; T407-C409 VanDerWaalsContact C-N 3.3Å; T407-C409 PolarHBondContact O-N 3.19Å; C409-L413 PolarHBondContact O-N 3.1Å; C409-W455 PolarHBondContact O-NE1 3.03Å; C409-M458 HydrophobicContact CB-CE 4.35Å
410D75.7Confident75.5Confident22 Ų2241 Ų4112%0.11820%0.204CC..Hα-helixtrans-77.2-39.2179-63.3-19.1000111.2R69 Y406 T407 F408 L413 S414 L584 Y588R69-D410 IonicContact CZ-OD1 3.97Å; R69-D410 IonicContact NE-OD1 3.17Å; R69-D410 PolarHBondContact NE-OD1 3.32Å; R69-D410 VanDerWaalsContact NE-OD1 3.13Å; R69-D410 IonicContact NH2-OD1 3.34Å; R69-D410 PolarHBondContact NH2-OD1 3.4Å; R69-D410 IonicContact NH2-OD2 3.07Å; R69-D410 PolarHBondContact NH2-OD2 3.49Å; Y406-D410 VanDerWaalsContact CE1-OD2 3.27Å; Y406-D410 WeakPolarHBondContact CE1-OD2 3.49Å; Y406-D410 PolarHBondContact O-N 3.47Å; T407-D410 PolarHBondContact O-N 3.48Å; T407-D410 VanDerWaalsContact O-N 3.12Å; F408-D410 VanDerWaalsContact C-N 3.31Å; F408-D410 PolarHBondContact O-N 3.07Å; D410-L413 PolarHBondContact O-N 3.46Å; D410-S414 PolarHBondContact O-N 3.09Å; D410-S414 VanDerWaalsContact O-N 3.14Å; D410-L584 HydrophobicContact CB-CD1 3.77Å; D410-Y588 VanDerWaalsContact CB-OH 3.27Å; D410-Y588 WeakPolarHBondContact CB-OH 3.12Å; D410-Y588 PolarHBondContact OD2-OH 2.74Å
411W78.1Confident74.8Confident99 Ų9939.4 Ų39.438%0.37519%0.194SC..Hα-helixtrans-63.9-40.2174.7178.482.2000112.3T407 F408 L413 S414 N415 F443T407-W411 PolarHBondContact O-N 3.39Å; F408-W411 AromaticContact CD2-CE3 3.91Å; F408-W411 HydrophobicContact CD2-CE3 3.91Å; F408-W411 HydrophobicContact CD2-CZ3 4.3Å; F408-W411 AromaticContact CE2-CE3 3.68Å; F408-W411 HydrophobicContact CE2-CE3 3.68Å; F408-W411 AromaticContact CE2-CZ3 3.63Å; F408-W411 HydrophobicContact CE2-CZ3 3.63Å; F408-W411 HydrophobicContact CZ-CZ3 4.38Å; F408-W411 PolarHBondContact O-N 3.26Å; W411-L413 VanDerWaalsContact C-N 3.33Å; W411-L413 PolarHBondContact O-N 3.15Å; W411-S414 WeakPolarHBondContact O-CB 3.45Å; W411-S414 PolarHBondContact O-N 2.82Å; W411-N415 WeakPolarHBondContact CH2-ND2 3.3Å; W411-N415 WeakPolarHBondContact CZ2-ND2 3.29Å; W411-N415 PolarHBondContact O-N 3.03Å; W411-F443 HydrophobicContact CH2-CZ 4.06Å; W411-F443 AromaticContact CZ3-CZ 3.96Å; W411-F443 HydrophobicContact CZ3-CZ 3.96Å
412W82.4Confident73.8Confident13 Ų1336.2 Ų36.25%0.04918%0.177CC..Hα-helixtrans-56.9-47175.9-171.4-82.2000111.6F408 S414 N415 E416 F442 F443 H451 I454 M458F408-W412 HydrophobicContact CE1-CE3 4.12Å; F408-W412 AromaticContact CZ-CE3 3.77Å; F408-W412 HydrophobicContact CZ-CE3 3.77Å; F408-W412 HydrophobicContact CZ-CZ3 4.13Å; F408-W412 WeakPolarHBondContact O-CB 3.47Å; F408-W412 PolarHBondContact O-N 2.91Å; W412-S414 PolarHBondContact O-N 2.84Å; W412-N415 PolarHBondContact O-N 2.96Å; W412-E416 PolarHBondContact O-N 2.99Å; W412-E416 VanDerWaalsContact O-N 3.14Å; W412-F442 HydrophobicContact CH2-CE1 4.34Å; W412-F443 HydrophobicContact CD2-CE1 4.09Å; W412-F443 AromaticContact CE3-CE1 3.61Å; W412-F443 HydrophobicContact CE3-CE1 3.61Å; W412-F443 HydrophobicContact CE3-CZ 4.16Å; W412-F443 AromaticContact CH2-CD1 3.87Å; W412-F443 HydrophobicContact CH2-CD1 3.87Å; W412-F443 AromaticContact CH2-CE1 3.32Å; W412-F443 HydrophobicContact CH2-CE1 3.32Å; W412-F443 HydrophobicContact CH2-CZ 4.12Å; W412-F443 HydrophobicContact CZ2-CD1 4.09Å; W412-F443 AromaticContact CZ2-CE1 3.82Å; W412-F443 HydrophobicContact CZ2-CE1 3.82Å; W412-F443 HydrophobicContact CZ3-CD1 4.21Å; W412-F443 AromaticContact CZ3-CE1 3.21Å; W412-F443 HydrophobicContact CZ3-CE1 3.21Å; W412-F443 AromaticContact CZ3-CZ 3.68Å; W412-F443 HydrophobicContact CZ3-CZ 3.68Å; W412-H451 AromaticContact CZ2-ND1 3.86Å; W412-H451 AromaticContact NE1-ND1 3.82Å; W412-I454 HydrophobicContact CH2-CG2 4.3Å; W412-I454 HydrophobicContact CZ2-CD1 4.3Å; W412-I454 HydrophobicContact CZ2-CG2 3.86Å; W412-M458 HydrophobicContact CB-CE 4.31Å; W412-M458 HydrophobicContact CD2-SD 4.29Å; W412-M458 HydrophobicContact CG-SD 4.36Å
413L75.6Confident72.7Confident22 Ų2240.3 Ų40.312%0.11520%0.202CC..Hα-helixtrans-63-40.1178.6-17268.3000112.2L72 V91 C409 D410 W411 W455L72-L413 HydrophobicContact CD2-CD2 4.07Å; V91-L413 HydrophobicContact CG1-CD1 3.95Å; V91-L413 HydrophobicContact CG1-CD2 3.77Å; V91-L413 HydrophobicContact CG1-CG 3.95Å; C409-L413 PolarHBondContact O-N 3.1Å; D410-L413 PolarHBondContact O-N 3.46Å; W411-L413 VanDerWaalsContact C-N 3.33Å; W411-L413 PolarHBondContact O-N 3.15Å; L413-W455 HydrophobicContact CD2-CZ2 4.41Å
414S71.9Confident71.9Confident1 Ų144.1 Ų44.11%0.00723%0.227CC..Hα-helixtrans-63.4-46177.3178.50000112.6D410 W411 W412 E417 D418 G580 T581D410-S414 PolarHBondContact O-N 3.09Å; D410-S414 VanDerWaalsContact O-N 3.14Å; W411-S414 WeakPolarHBondContact O-CB 3.45Å; W411-S414 PolarHBondContact O-N 2.82Å; W412-S414 PolarHBondContact O-N 2.84Å; S414-E417 WeakPolarHBondContact O-CB 3.45Å; S414-E417 PolarHBondContact O-N 3.11Å; S414-D418 PolarHBondContact O-N 3.39Å; S414-G580 WeakPolarHBondContact OG-CA 3.42Å; S414-G580 PolarHBondContact OG-O 2.92Å; S414-G580 VanDerWaalsContact OG-O 3.12Å; S414-T581 PolarHBondContact OG-N 3.4Å; S414-T581 VanDerWaalsContact OG-N 3.08Å
415N70.5Confident70.9Confident22 Ų2247.6 Ų47.612%0.11823%0.233CC..Hα-helixtrans-70.1-38-177.2-82-1.6000113.1W411 W412 E417 D418 I419W411-N415 WeakPolarHBondContact CH2-ND2 3.3Å; W411-N415 WeakPolarHBondContact CZ2-ND2 3.29Å; W411-N415 PolarHBondContact O-N 3.03Å; W412-N415 PolarHBondContact O-N 2.96Å; N415-E417 PolarHBondContact O-N 3.34Å; N415-D418 PolarHBondContact O-N 3.05Å; N415-I419 VanDerWaalsContact O-CG1 3.28Å; N415-I419 WeakPolarHBondContact O-CG1 3.33Å; N415-I419 PolarHBondContact O-N 3.27Å
416E68Low69.7Low24 Ų2450.2 Ų50.211%0.11224%0.243CC..Hα-helixtrans-56.1-38.3176-171-171.8161.800110.6W412 R420 H451W412-E416 PolarHBondContact O-N 2.99Å; W412-E416 VanDerWaalsContact O-N 3.14Å; E416-R420 WeakPolarHBondContact O-CG 3.41Å; E416-R420 PolarHBondContact O-N 2.8Å; E416-R420 IonicContact OE1-CZ 2.75Å; E416-R420 IonicContact OE1-NE 3.86Å; E416-R420 PolarHBondContact OE1-NE 2.94Å; E416-R420 VanDerWaalsContact OE1-NE 3.14Å; E416-R420 IonicContact OE1-NH2 3.38Å; E416-R420 PolarHBondContact OE1-NH2 3.07Å; E416-H451 HydrophobicContact CG-CB 4.4Å; E416-H451 WeakPolarHBondContact OE1-CB 3.27Å; E416-H451 IonicContact OE1-CG 3.9Å
417E64.3Low68.5Low15 Ų1553.8 Ų53.87%0.0727%0.268CS..Hα-helixtrans-71-44.5178.7-165.3-174.2121.400113.3S88 F92 S414 N415 I419 R420 K421S88-E417 VanDerWaalsContact CA-CD 3.5Å; S88-E417 VanDerWaalsContact CA-OE2 3.3Å; S88-E417 WeakPolarHBondContact CA-OE2 3.5Å; S88-E417 WeakPolarHBondContact CB-OE1 3.41Å; S88-E417 WeakPolarHBondContact CB-OE2 3.21Å; F92-E417 VanDerWaalsContact CD2-OE2 3.27Å; F92-E417 WeakPolarHBondContact CD2-OE2 3.4Å; F92-E417 VanDerWaalsContact CE2-CD 3.44Å; F92-E417 WeakPolarHBondContact CE2-OE1 3.47Å; F92-E417 WeakPolarHBondContact CE2-OE2 3.45Å; S414-E417 WeakPolarHBondContact O-CB 3.45Å; S414-E417 PolarHBondContact O-N 3.11Å; N415-E417 PolarHBondContact O-N 3.34Å; E417-I419 PolarHBondContact O-N 2.97Å; E417-R420 PolarHBondContact O-N 3.43Å; E417-R420 VanDerWaalsContact O-N 3.11Å; E417-K421 PolarHBondContact O-N 3.46Å; E417-K421 IonicContact OE1-NZ 3.87Å; E417-K421 PolarHBondContact OE1-NZ 3.11Å
418D65.3Low67.4Low19 Ų1957.7 Ų57.710%0.10229%0.287CS..Hα-helixtrans-60.5-36.5177-73.3-34000110.8S414 N415 L422 S579 G580 T581S414-D418 PolarHBondContact O-N 3.39Å; N415-D418 PolarHBondContact O-N 3.05Å; D418-L422 WeakPolarHBondContact O-CB 3.4Å; D418-L422 WeakPolarHBondContact O-CD1 3.42Å; D418-L422 VanDerWaalsContact O-CG 3.24Å; D418-L422 WeakPolarHBondContact O-CG 2.95Å; D418-L422 PolarHBondContact O-N 3.47Å; D418-L422 VanDerWaalsContact O-N 3.08Å; D418-S579 PolarHBondContact OD1-N 3.3Å; D418-G580 WeakPolarHBondContact OD1-CA 3.47Å; D418-G580 PolarHBondContact OD1-N 2.99Å; D418-T581 PolarHBondContact OD2-N 3.07Å
419I64Low65.9Low23 Ų2358.1 Ų58.112%0.11829%0.293CS..Hα-helixtrans-64.8-48172.1-63.9167.1000111.2N415 E417 K421 L422 V423 L440 F443 T444N415-I419 VanDerWaalsContact O-CG1 3.28Å; N415-I419 WeakPolarHBondContact O-CG1 3.33Å; N415-I419 PolarHBondContact O-N 3.27Å; E417-I419 PolarHBondContact O-N 2.97Å; I419-K421 VanDerWaalsContact C-N 3.35Å; I419-K421 PolarHBondContact O-N 2.98Å; I419-L422 PolarHBondContact O-N 3.39Å; I419-V423 WeakPolarHBondContact O-CG2 3.48Å; I419-V423 PolarHBondContact O-N 3.3Å; I419-L440 HydrophobicContact CD1-CD2 3.53Å; I419-L440 HydrophobicContact CG1-CD2 3.71Å; I419-F443 HydrophobicContact CD1-CB 3.51Å; I419-F443 HydrophobicContact CD1-CG 4.19Å; I419-T444 HydrophobicContact CG2-CG2 4.15Å
420R63.4Low64.6Low94 Ų9463.1 Ų63.136%0.35532%0.319SS..Hα-helixtrans-60-43.9179.6-77175.3-174-118.810111.6E416 E417 V423 T424E416-R420 WeakPolarHBondContact O-CG 3.41Å; E416-R420 PolarHBondContact O-N 2.8Å; E416-R420 IonicContact OE1-CZ 2.75Å; E416-R420 IonicContact OE1-NE 3.86Å; E416-R420 PolarHBondContact OE1-NE 2.94Å; E416-R420 VanDerWaalsContact OE1-NE 3.14Å; E416-R420 IonicContact OE1-NH2 3.38Å; E416-R420 PolarHBondContact OE1-NH2 3.07Å; E417-R420 PolarHBondContact O-N 3.43Å; E417-R420 VanDerWaalsContact O-N 3.11Å; R420-V423 PolarHBondContact O-N 3.14Å; R420-T424 WeakPolarHBondContact O-CG2 3.38Å; R420-T424 PolarHBondContact O-N 3.15Å; R420-T424 PolarHBondContact O-OG1 3.05Å
421K62.7Low63.8Low57 Ų5767.1 Ų67.125%0.24834%0.344CS..Hα-helixtrans-62.9-44.9177.4-82175172.5158.20112S88 E417 I419 V423 T424 M425 S579S88-K421 WeakPolarHBondContact OG-CE 3.47Å; S88-K421 PolarHBondContact OG-NZ 3.04Å; S88-K421 VanDerWaalsContact OG-NZ 3.09Å; E417-K421 PolarHBondContact O-N 3.46Å; E417-K421 IonicContact OE1-NZ 3.87Å; E417-K421 PolarHBondContact OE1-NZ 3.11Å; I419-K421 VanDerWaalsContact C-N 3.35Å; I419-K421 PolarHBondContact O-N 2.98Å; K421-V423 VanDerWaalsContact C-N 3.31Å; K421-V423 PolarHBondContact O-N 2.81Å; K421-T424 WeakPolarHBondContact CA-OG1 3.13Å; K421-T424 PolarHBondContact O-N 3.39Å; K421-T424 PolarHBondContact O-OG1 3.03Å; K421-M425 VanDerWaalsContact O-CB 3.22Å; K421-M425 WeakPolarHBondContact O-CB 3.33Å; K421-M425 PolarHBondContact O-N 3.22Å; K421-S579 WeakPolarHBondContact CD-OG 3.42Å; K421-S579 WeakPolarHBondContact CE-OG 3.43Å; K421-S579 PolarHBondContact NZ-OG 3.24Å
422L60.7Low62.7Low54 Ų5467.7 Ų67.728%0.28335%0.353SS..Hα-helixtrans-58.3-41.9176.1-76.9165.7000112.2D418 I419 Y426D418-L422 WeakPolarHBondContact O-CB 3.4Å; D418-L422 WeakPolarHBondContact O-CD1 3.42Å; D418-L422 VanDerWaalsContact O-CG 3.24Å; D418-L422 WeakPolarHBondContact O-CG 2.95Å; D418-L422 PolarHBondContact O-N 3.47Å; D418-L422 VanDerWaalsContact O-N 3.08Å; I419-L422 PolarHBondContact O-N 3.39Å; L422-Y426 PolarHBondContact O-N 2.95Å
423V61.2Low61.2Low91 Ų9169 Ų6955%0.55237%0.368SS*.Hα-helixtrans-67.8-39.4177.6174.20000111.9I419 R420 K421I419-V423 WeakPolarHBondContact O-CG2 3.48Å; I419-V423 PolarHBondContact O-N 3.3Å; R420-V423 PolarHBondContact O-N 3.14Å; K421-V423 VanDerWaalsContact C-N 3.31Å; K421-V423 PolarHBondContact O-N 2.81Å
424T60.8Low60.2Low109 Ų10973.4 Ų73.467%0.66939%0.388SS*.Hα-helixtrans-75.8-31.3179.854.50000114.2R420 K421R420-T424 WeakPolarHBondContact O-CG2 3.38Å; R420-T424 PolarHBondContact O-N 3.15Å; R420-T424 PolarHBondContact O-OG1 3.05Å; K421-T424 WeakPolarHBondContact CA-OG1 3.13Å; K421-T424 PolarHBondContact O-N 3.39Å; K421-T424 PolarHBondContact O-OG1 3.03Å
425M56.8Low59.4Low115 Ų11579.5 Ų79.557%0.56742%0.416SS*.Hα-helixtrans-85.5-21.5-172.8-163.5177.8-88.200112.4K421K421-M425 VanDerWaalsContact O-CB 3.22Å; K421-M425 WeakPolarHBondContact O-CB 3.33Å; K421-M425 PolarHBondContact O-N 3.22Å
426Y58.6Low58.5Low114 Ų11483.6 Ų83.645%0.44743%0.429SS..  trans-130.567.6179.7-62.3-74.5000111.5L422 D428 N429L422-Y426 PolarHBondContact O-N 2.95Å; Y426-D428 PolarHBondContact O-N 3.4Å; Y426-N429 HydrophobicContact CD1-CB 4.26Å
427P55.8Low57.8Low97 Ų9787.9 Ų87.963%0.6345%0.448SS*.SBendtrans-62.2-30.5179.423.8-31.2000112.5
428D54.3Low57.2Low136 Ų13695.3 Ų95.373%0.72748%0.48SS*.SBendtrans-117.90.2-169.3-60-43.7000115.5Y426 I430Y426-D428 PolarHBondContact O-N 3.4Å; D428-I430 PolarHBondContact O-N 3.43Å
429N51.1Low56.6Low93 Ų93103.4 Ų103.450%0.49751%0.509SS..  trans-96.474178.6-80.9-16.7000111.8Y426 T431 A433Y426-N429 HydrophobicContact CD1-CB 4.26Å; N429-T431 VanDerWaalsContact C-N 3.3Å; N429-T431 PolarHBondContact O-N 2.98Å; N429-A433 WeakPolarHBondContact O-CB 3.3Å; N429-A433 PolarHBondContact O-N 2.83Å
430I56.2Low56.2Low105 Ų105104.8 Ų104.854%0.53852%0.516SS..Hα-helixtrans-57.8-33.8-170.5-63.9167.8000113.1D428 E434D428-I430 PolarHBondContact O-N 3.43Å; I430-E434 VanDerWaalsContact CG2-CD 3.42Å; I430-E434 HydrophobicContact CG2-CG 4.04Å; I430-E434 WeakPolarHBondContact CG2-OE1 3.3Å; I430-E434 WeakPolarHBondContact O-CB 3.34Å; I430-E434 WeakPolarHBondContact O-CG 3.35Å; I430-E434 PolarHBondContact O-N 3.01Å
431T57.3Low55.4Low106 Ų106104.2 Ų104.265%0.6553%0.527SS*.Hα-helixtrans-77-42.2-170.246.80000114.9N429 E435N429-T431 VanDerWaalsContact C-N 3.3Å; N429-T431 PolarHBondContact O-N 2.98Å; T431-E435 PolarHBondContact O-N 2.98Å
432I55.6Low55Low111 Ų111108.1 Ų108.157%0.56954%0.544SS*.Hα-helixtrans-77.7-35.8177.8-56.9176.9000110.1R436I432-R436 PolarHBondContact O-N 3.2Å; I432-R436 VanDerWaalsContact O-N 3.17Å
433A51.6Low54.6Low42 Ų42106.9 Ų106.935%0.34754%0.536SS..Hα-helixtrans-63.7-42.8174.500000111.1N429 K437N429-A433 WeakPolarHBondContact O-CB 3.3Å; N429-A433 PolarHBondContact O-N 2.83Å; A433-K437 WeakPolarHBondContact O-CB 3.49Å; A433-K437 PolarHBondContact O-N 3.35Å
434E54Low54.1Low114 Ų114104.8 Ų104.853%0.53352%0.524SS..Hα-helixtrans-68.1-38.9177.9-82.3179.6161.900113.8I430 K437 K438I430-E434 VanDerWaalsContact CG2-CD 3.42Å; I430-E434 HydrophobicContact CG2-CG 4.04Å; I430-E434 WeakPolarHBondContact CG2-OE1 3.3Å; I430-E434 WeakPolarHBondContact O-CB 3.34Å; I430-E434 WeakPolarHBondContact O-CG 3.35Å; I430-E434 PolarHBondContact O-N 3.01Å; E434-K437 PolarHBondContact O-N 3.35Å; E434-K438 WeakPolarHBondContact O-CB 3.5Å; E434-K438 PolarHBondContact O-N 2.96Å
435E54.4Low53.9Low128 Ų128102.7 Ų102.760%0.59852%0.524SS*.Hα-helixtrans-66.7-36.9176.5-105.2-172.2172.700112.6T431 R439T431-E435 PolarHBondContact O-N 2.98Å; E435-R439 PolarHBondContact O-N 3.43Å
436R53.4Low54.2Low108 Ų108100.8 Ų100.841%0.40851%0.513SS..Hα-helixtrans-77.8-34.2172.7-76.8-177.4173.7-168.6-3.6112.1I432 K438 R439 L440I432-R436 PolarHBondContact O-N 3.2Å; I432-R436 VanDerWaalsContact O-N 3.17Å; R436-K438 VanDerWaalsContact C-N 3.3Å; R436-K438 PolarHBondContact O-N 3.35Å; R436-R439 PolarHBondContact O-N 3.14Å; R436-R439 VanDerWaalsContact O-N 3.17Å; R436-L440 WeakPolarHBondContact O-CD1 3.44Å; R436-L440 PolarHBondContact O-N 3.12Å
437K51.9Low54.5Low115 Ų115101 Ų10150%0.552%0.521SS..Hα-helixtrans-59.3-38.5169.8-117.5175.4172.2179.40111.6A433 E434 L440 S441 T444A433-K437 WeakPolarHBondContact O-CB 3.49Å; A433-K437 PolarHBondContact O-N 3.35Å; E434-K437 PolarHBondContact O-N 3.35Å; K437-L440 CarbonylContact O-C 3.56Å; K437-L440 PolarHBondContact O-N 3.27Å; K437-S441 WeakPolarHBondContact O-CA 3.4Å; K437-S441 PolarHBondContact O-N 3.34Å; K437-T444 HydrophobicContact CG-CG2 3.79Å
438K52.9Low55Low170 Ų17099.2 Ų99.274%0.73951%0.512SS*.Hα-helixtrans-64.9-43.1173.4-97.5178.7174.3172.50112.2E434 R436 L440 S441E434-K438 WeakPolarHBondContact O-CB 3.5Å; E434-K438 PolarHBondContact O-N 2.96Å; R436-K438 VanDerWaalsContact C-N 3.3Å; R436-K438 PolarHBondContact O-N 3.35Å; K438-L440 VanDerWaalsContact C-N 3.32Å; K438-L440 PolarHBondContact O-N 2.78Å; K438-S441 WeakPolarHBondContact O-CB 3.14Å; K438-S441 PolarHBondContact O-N 2.88Å; K438-S441 PolarHBondContact O-OG 3.24Å
439R52.4Low55.9Low190 Ų19096.4 Ų96.472%0.71750%0.499SS*.Hα-helixtrans-67.5-29.3175.5-93.9-175-84.7-158.2-6.8113.6E435 R436E435-R439 PolarHBondContact O-N 3.43Å; R436-R439 PolarHBondContact O-N 3.14Å; R436-R439 VanDerWaalsContact O-N 3.17Å
440L54.6Low57.1Low52 Ų5295.8 Ų95.827%0.27249%0.493SS..THydrogen-bonded Turntrans-108.728.2175.1-76.1109.2000112.6I419 R436 K437 K438 F442 F443 T444I419-L440 HydrophobicContact CD1-CD2 3.53Å; I419-L440 HydrophobicContact CG1-CD2 3.71Å; R436-L440 WeakPolarHBondContact O-CD1 3.44Å; R436-L440 PolarHBondContact O-N 3.12Å; K437-L440 CarbonylContact O-C 3.56Å; K437-L440 PolarHBondContact O-N 3.27Å; K438-L440 VanDerWaalsContact C-N 3.32Å; K438-L440 PolarHBondContact O-N 2.78Å; L440-F442 PolarHBondContact O-N 2.85Å; L440-F442 VanDerWaalsContact O-N 3.09Å; L440-F443 HydrophobicContact CD2-CD2 4.34Å; L440-F443 PolarHBondContact O-N 3.24Å; L440-T444 HydrophobicContact CB-CG2 4.18Å; L440-T444 WeakPolarHBondContact O-CG2 3.09Å; L440-T444 PolarHBondContact O-N 2.75Å; L440-T444 VanDerWaalsContact O-N 3.07Å; L440-T444 PolarHBondContact O-OG1 3.25Å; L440-T444 VanDerWaalsContact O-OG1 3.1Å
441S46.8Very low58Low82 Ų8291.3 Ų91.357%0.57347%0.47SS*.THydrogen-bonded Turntrans-59.4-27.4-175.948.30000112.6K437 K438 F443K437-S441 WeakPolarHBondContact O-CA 3.4Å; K437-S441 PolarHBondContact O-N 3.34Å; K438-S441 WeakPolarHBondContact O-CB 3.14Å; K438-S441 PolarHBondContact O-N 2.88Å; K438-S441 PolarHBondContact O-OG 3.24Å; S441-F443 VanDerWaalsContact C-N 3.32Å; S441-F443 PolarHBondContact O-N 3.14Å
442F54.3Low59Low139 Ų13988.4 Ų88.461%0.6145%0.45SS*.THydrogen-bonded Turntrans-65.1-31.6172.7-171.3-99.6000113.7W412 L440 F446W412-F442 HydrophobicContact CH2-CE1 4.34Å; L440-F442 PolarHBondContact O-N 2.85Å; L440-F442 VanDerWaalsContact O-N 3.09Å; F442-F446 WeakPolarHBondContact O-CE2 3.24Å
443F51.8Low60.3Low27 Ų2789.8 Ų89.812%0.11845%0.452CS..THydrogen-bonded Turntrans-100.1-24-173.8-71.8-88.8000113.9W411 W412 I419 L440 S441 G445 H451W411-F443 HydrophobicContact CH2-CZ 4.06Å; W411-F443 AromaticContact CZ3-CZ 3.96Å; W411-F443 HydrophobicContact CZ3-CZ 3.96Å; W412-F443 HydrophobicContact CD2-CE1 4.09Å; W412-F443 AromaticContact CE3-CE1 3.61Å; W412-F443 HydrophobicContact CE3-CE1 3.61Å; W412-F443 HydrophobicContact CE3-CZ 4.16Å; W412-F443 AromaticContact CH2-CD1 3.87Å; W412-F443 HydrophobicContact CH2-CD1 3.87Å; W412-F443 AromaticContact CH2-CE1 3.32Å; W412-F443 HydrophobicContact CH2-CE1 3.32Å; W412-F443 HydrophobicContact CH2-CZ 4.12Å; W412-F443 HydrophobicContact CZ2-CD1 4.09Å; W412-F443 AromaticContact CZ2-CE1 3.82Å; W412-F443 HydrophobicContact CZ2-CE1 3.82Å; W412-F443 HydrophobicContact CZ3-CD1 4.21Å; W412-F443 AromaticContact CZ3-CE1 3.21Å; W412-F443 HydrophobicContact CZ3-CE1 3.21Å; W412-F443 AromaticContact CZ3-CZ 3.68Å; W412-F443 HydrophobicContact CZ3-CZ 3.68Å; I419-F443 HydrophobicContact CD1-CB 3.51Å; I419-F443 HydrophobicContact CD1-CG 4.19Å; L440-F443 HydrophobicContact CD2-CD2 4.34Å; L440-F443 PolarHBondContact O-N 3.24Å; S441-F443 VanDerWaalsContact C-N 3.32Å; S441-F443 PolarHBondContact O-N 3.14Å; F443-G445 VanDerWaalsContact C-N 3.33Å; F443-G445 PolarHBondContact O-N 3.43Å; F443-H451 PolarHBondContact O-CE1 3.36Å; F443-H451 PolarHBondContact O-NE2 3.4Å; F443-H451 VanDerWaalsContact O-NE2 3.15Å
444T52.1Low62Low48 Ų4890.1 Ų90.129%0.29445%0.448SS..THydrogen-bonded Turntrans-84.8-4.9-170.750.70000114.2I419 K437 L440I419-T444 HydrophobicContact CG2-CG2 4.15Å; K437-T444 HydrophobicContact CG-CG2 3.79Å; L440-T444 HydrophobicContact CB-CG2 4.18Å; L440-T444 WeakPolarHBondContact O-CG2 3.09Å; L440-T444 PolarHBondContact O-N 2.75Å; L440-T444 VanDerWaalsContact O-N 3.07Å; L440-T444 PolarHBondContact O-OG1 3.25Å; L440-T444 VanDerWaalsContact O-OG1 3.1Å
445G56Low63.5Low65 Ų6585 Ų8567%0.6742%0.423SS*.THydrogen-bonded Turntrans-89.7-7.317600000115.2F443F443-G445 VanDerWaalsContact C-N 3.33Å; F443-G445 PolarHBondContact O-N 3.43Å
446F63Low65.1Low74 Ų7481.1 Ų81.133%0.32541%0.409SS..SBendtrans-97.6133-175.2-65.3-65.7000112.2F442 E450 H451 I454F442-F446 WeakPolarHBondContact O-CE2 3.24Å; F446-E450 VanDerWaalsContact CA-OE2 3.24Å; F446-E450 WeakPolarHBondContact CA-OE2 3.31Å; F446-E450 HydrophobicContact CB-CB 4Å; F446-E450 HydrophobicContact CD1-CB 4.02Å; F446-E450 WeakPolarHBondContact CD1-OE2 3.41Å; F446-E450 HydrophobicContact CG-CB 4.43Å; F446-H451 WeakPolarHBondContact CB-NE2 3.46Å; F446-H451 PolarHBondContact O-CD2 2.99Å; F446-I454 HydrophobicContact CD1-CD1 4.26Å; F446-I454 HydrophobicContact CD2-CD1 4.36Å; F446-I454 HydrophobicContact CE1-CD1 4.19Å; F446-I454 HydrophobicContact CE2-CD1 4.28Å; F446-I454 HydrophobicContact CG-CD1 4.36Å; F446-I454 HydrophobicContact CZ-CD1 4.2Å
447D65.8Low66.9Low118 Ų11879.9 Ų79.963%0.63142%0.415SS*.  trans-66.5157.2170.6-91.4-16.8000111.1V449 E450 H451D447-V449 PolarHBondContact O-N 3.08Å; D447-E450 HydrophobicContact CB-CG 4.22Å; D447-E450 PolarHBondContact N-OE2 3.31Å; D447-E450 WeakPolarHBondContact O-CA 3.5Å; D447-E450 WeakPolarHBondContact O-CB 3.48Å; D447-E450 PolarHBondContact O-N 3.39Å; D447-H451 PolarHBondContact O-N 2.69Å
448S65.9Low68.7Low61 Ų6175.1 Ų75.143%0.42740%0.395SS..Hα-helixtrans-51.7-32.3176.959.50000113.6L452S448-L452 PolarHBondContact O-N 3.03Å
449V72.5Confident70.5Confident77 Ų7767.2 Ų67.247%0.46736%0.361SS..Hα-helixtrans-73.1-35176.1178.40000111.6D447 L452 K453D447-V449 PolarHBondContact O-N 3.08Å; V449-L452 PolarHBondContact O-N 2.91Å; V449-K453 HydrophobicContact CG1-CD 4.43Å; V449-K453 VanDerWaalsContact O-CG 3.32Å; V449-K453 WeakPolarHBondContact O-CG 3.22Å; V449-K453 PolarHBondContact O-N 3.26Å
450E77.5Confident72.3Confident79 Ų7961.8 Ų61.837%0.36935%0.349SS..Hα-helixtrans-72.5-41.1179.7-63.9-177.8145.600111.4F446 D447 L452 K453 I454F446-E450 VanDerWaalsContact CA-OE2 3.24Å; F446-E450 WeakPolarHBondContact CA-OE2 3.31Å; F446-E450 HydrophobicContact CB-CB 4Å; F446-E450 HydrophobicContact CD1-CB 4.02Å; F446-E450 WeakPolarHBondContact CD1-OE2 3.41Å; F446-E450 HydrophobicContact CG-CB 4.43Å; D447-E450 HydrophobicContact CB-CG 4.22Å; D447-E450 PolarHBondContact N-OE2 3.31Å; D447-E450 WeakPolarHBondContact O-CA 3.5Å; D447-E450 WeakPolarHBondContact O-CB 3.48Å; D447-E450 PolarHBondContact O-N 3.39Å; E450-L452 VanDerWaalsContact C-N 3.32Å; E450-L452 PolarHBondContact O-N 3.3Å; E450-K453 WeakPolarHBondContact O-CB 3.44Å; E450-K453 PolarHBondContact O-N 2.72Å; E450-I454 WeakPolarHBondContact O-CG1 3.41Å; E450-I454 PolarHBondContact O-N 3.3Å
451H73.8Confident74.1Confident11 Ų1162.1 Ų62.15%0.05135%0.353CS..Hα-helixtrans-56.7-45.7170.7-80.6-65000111.9W412 E416 F443 F446 D447 K453 I454 W455W412-H451 AromaticContact CZ2-ND1 3.86Å; W412-H451 AromaticContact NE1-ND1 3.82Å; E416-H451 HydrophobicContact CG-CB 4.4Å; E416-H451 WeakPolarHBondContact OE1-CB 3.27Å; E416-H451 IonicContact OE1-CG 3.9Å; F443-H451 PolarHBondContact O-CE1 3.36Å; F443-H451 PolarHBondContact O-NE2 3.4Å; F443-H451 VanDerWaalsContact O-NE2 3.15Å; F446-H451 WeakPolarHBondContact CB-NE2 3.46Å; F446-H451 PolarHBondContact O-CD2 2.99Å; D447-H451 PolarHBondContact O-N 2.69Å; H451-K453 VanDerWaalsContact C-N 3.34Å; H451-K453 PolarHBondContact O-N 3Å; H451-I454 PolarHBondContact O-N 3.49Å; H451-W455 WeakPolarHBondContact O-CB 3.2Å; H451-W455 PolarHBondContact O-N 2.7Å
452L78.3Confident76.1Confident45 Ų4558.2 Ų58.224%0.23633%0.326CS..Hα-helixtrans-63.3-38.3177.4-169.166.8000112.3L73 S448 V449 E450 W455 T456L73-L452 HydrophobicContact CD1-CD1 3.6Å; L73-L452 HydrophobicContact CD1-CG 4.18Å; S448-L452 PolarHBondContact O-N 3.03Å; V449-L452 PolarHBondContact O-N 2.91Å; E450-L452 VanDerWaalsContact C-N 3.32Å; E450-L452 PolarHBondContact O-N 3.3Å; L452-W455 HydrophobicContact CD1-CE3 4.16Å; L452-T456 WeakPolarHBondContact O-CB 3.3Å; L452-T456 PolarHBondContact O-N 2.72Å; L452-T456 PolarHBondContact O-OG1 3.29Å
453K84.6Confident77.9Confident140 Ų14054.1 Ų54.161%0.60931%0.31SS*.Hα-helixtrans-64.2-45.4175.1-76.1171.2-1801740111.7V449 E450 H451 T456 C457V449-K453 HydrophobicContact CG1-CD 4.43Å; V449-K453 VanDerWaalsContact O-CG 3.32Å; V449-K453 WeakPolarHBondContact O-CG 3.22Å; V449-K453 PolarHBondContact O-N 3.26Å; E450-K453 WeakPolarHBondContact O-CB 3.44Å; E450-K453 PolarHBondContact O-N 2.72Å; H451-K453 VanDerWaalsContact C-N 3.34Å; H451-K453 PolarHBondContact O-N 3Å; K453-T456 WeakPolarHBondContact O-CB 3.11Å; K453-T456 PolarHBondContact O-N 2.98Å; K453-C457 PolarHBondContact O-N 3.12Å
454I86Confident79.8Confident50 Ų5058.4 Ų58.426%0.25633%0.333SS..Hα-helixtrans-61.7-48.4177.4-66.9166.2000109.8W412 F446 E450 H451 T456 C457 M458W412-I454 HydrophobicContact CH2-CG2 4.3Å; W412-I454 HydrophobicContact CZ2-CD1 4.3Å; W412-I454 HydrophobicContact CZ2-CG2 3.86Å; F446-I454 HydrophobicContact CD1-CD1 4.26Å; F446-I454 HydrophobicContact CD2-CD1 4.36Å; F446-I454 HydrophobicContact CE1-CD1 4.19Å; F446-I454 HydrophobicContact CE2-CD1 4.28Å; F446-I454 HydrophobicContact CG-CD1 4.36Å; F446-I454 HydrophobicContact CZ-CD1 4.2Å; E450-I454 WeakPolarHBondContact O-CG1 3.41Å; E450-I454 PolarHBondContact O-N 3.3Å; H451-I454 PolarHBondContact O-N 3.49Å; I454-T456 VanDerWaalsContact C-N 3.3Å; I454-T456 PolarHBondContact O-N 2.96Å; I454-C457 WeakPolarHBondContact O-CB 3.29Å; I454-C457 PolarHBondContact O-N 3.23Å; I454-C457 VanDerWaalsContact O-N 3.12Å; I454-M458 HydrophobicContact CG2-SD 4.01Å; I454-M458 WeakPolarHBondContact O-CG 3.13Å; I454-M458 PolarHBondContact O-N 3.06Å
455W85.2Confident81.6Confident6 Ų658.5 Ų58.52%0.02333%0.334CS..Hα-helixtrans-62-37.7178.6-170.165.6000112.3R69 L72 L73 L76 C409 L413 H451 L452 M458 I459R69-W455 HydrophobicContact CB-CZ2 4.47Å; L72-W455 HydrophobicContact CB-CH2 4.22Å; L72-W455 HydrophobicContact CD2-CH2 3.85Å; L72-W455 HydrophobicContact CD2-CZ2 4.22Å; L72-W455 HydrophobicContact CG-CH2 3.97Å; L73-W455 HydrophobicContact CB-CE3 4.44Å; L73-W455 HydrophobicContact CB-CH2 4.3Å; L73-W455 HydrophobicContact CB-CZ3 3.68Å; L73-W455 HydrophobicContact CD1-CE3 3.63Å; L73-W455 HydrophobicContact CD1-CZ3 3.61Å; L73-W455 HydrophobicContact CG-CZ3 4.26Å; L76-W455 HydrophobicContact CD1-CZ3 4.27Å; C409-W455 PolarHBondContact O-NE1 3.03Å; L413-W455 HydrophobicContact CD2-CZ2 4.41Å; H451-W455 WeakPolarHBondContact O-CB 3.2Å; H451-W455 PolarHBondContact O-N 2.7Å; L452-W455 HydrophobicContact CD1-CE3 4.16Å; W455-M458 WeakPolarHBondContact O-CB 3.3Å; W455-M458 PolarHBondContact O-N 3.22Å; W455-I459 HydrophobicContact CD2-CD1 3.64Å; W455-I459 HydrophobicContact CD2-CG1 4.44Å; W455-I459 HydrophobicContact CE3-CD1 3.69Å; W455-I459 HydrophobicContact CG-CD1 4.36Å; W455-I459 HydrophobicContact CH2-CD1 3.78Å; W455-I459 HydrophobicContact CZ2-CD1 3.75Å; W455-I459 HydrophobicContact CZ3-CD1 3.77Å; W455-I459 VanDerWaalsContact O-CG1 3.29Å; W455-I459 WeakPolarHBondContact O-CG1 3.5Å; W455-I459 PolarHBondContact O-N 3.35Å
456T87.7Confident83.1Confident47 Ų4755.5 Ų55.529%0.28830%0.302SS..Hα-helixtrans-60.7-46.2172.6-58.30000111.8L73 L452 K453 I454 M458 I459 V460L73-T456 WeakPolarHBondContact CD1-OG1 3.2Å; L73-T456 HydrophobicContact CD2-CG2 3.89Å; L452-T456 WeakPolarHBondContact O-CB 3.3Å; L452-T456 PolarHBondContact O-N 2.72Å; L452-T456 PolarHBondContact O-OG1 3.29Å; K453-T456 WeakPolarHBondContact O-CB 3.11Å; K453-T456 PolarHBondContact O-N 2.98Å; I454-T456 VanDerWaalsContact C-N 3.3Å; I454-T456 PolarHBondContact O-N 2.96Å; T456-M458 VanDerWaalsContact C-N 3.29Å; T456-M458 PolarHBondContact O-N 3.09Å; T456-I459 PolarHBondContact O-N 3.3Å; T456-V460 WeakPolarHBondContact O-CG2 3.39Å; T456-V460 PolarHBondContact O-N 3.1Å
457C91.4Very high84.3Confident81 Ų8153.2 Ų53.255%0.54730%0.295SS..Hα-helixtrans-60.8-39.6176.9-173.50000111.8K453 I454 V460 T461K453-C457 PolarHBondContact O-N 3.12Å; I454-C457 WeakPolarHBondContact O-CB 3.29Å; I454-C457 PolarHBondContact O-N 3.23Å; I454-C457 VanDerWaalsContact O-N 3.12Å; C457-V460 PolarHBondContact O-N 3.48Å; C457-T461 WeakPolarHBondContact O-CB 3.29Å; C457-T461 PolarHBondContact O-N 2.92Å; C457-T461 PolarHBondContact O-OG1 3Å
458M90.3Very high85.5Confident16 Ų1652 Ų528%0.07929%0.287CS..Hα-helixtrans-64.5-45175.4-66.6171.159.700111.8F405 F408 C409 W412 I454 W455 T456 V460 T461 L462F405-M458 HydrophobicContact CE1-CB 4.47Å; F405-M458 WeakPolarHBondContact CE1-O 3.4Å; F405-M458 HydrophobicContact CZ-CB 3.99Å; F405-M458 HydrophobicContact CZ-CG 4.16Å; F408-M458 HydrophobicContact CD1-CE 3.28Å; F408-M458 HydrophobicContact CE1-CE 3.46Å; F408-M458 VanDerWaalsContact CE1-CE 3.46Å; F408-M458 HydrophobicContact CE1-SD 4.24Å; F408-M458 HydrophobicContact CG-CE 4.33Å; C409-M458 HydrophobicContact CB-CE 4.35Å; W412-M458 HydrophobicContact CB-CE 4.31Å; W412-M458 HydrophobicContact CD2-SD 4.29Å; W412-M458 HydrophobicContact CG-SD 4.36Å; I454-M458 HydrophobicContact CG2-SD 4.01Å; I454-M458 WeakPolarHBondContact O-CG 3.13Å; I454-M458 PolarHBondContact O-N 3.06Å; W455-M458 WeakPolarHBondContact O-CB 3.3Å; W455-M458 PolarHBondContact O-N 3.22Å; T456-M458 VanDerWaalsContact C-N 3.29Å; T456-M458 PolarHBondContact O-N 3.09Å; M458-V460 PolarHBondContact O-N 3.1Å; M458-T461 PolarHBondContact O-N 3.15Å; M458-L462 WeakPolarHBondContact O-CB 3.47Å; M458-L462 PolarHBondContact O-N 3.29Å
459I89.9Confident86.5Confident3 Ų349.3 Ų49.32%0.01527%0.268CS..Hα-helixtrans-60-45.1176.7-70.6169.3000111.3V66 R69 I70 L73 W455 T456 L462 L463V66-I459 HydrophobicContact CG1-CB 4.46Å; V66-I459 HydrophobicContact CG1-CG2 3.35Å; R69-I459 HydrophobicContact CB-CD1 3.85Å; R69-I459 HydrophobicContact CB-CG1 4.02Å; R69-I459 HydrophobicContact CB-CG2 4.43Å; I70-I459 HydrophobicContact CG1-CG2 3.84Å; L73-I459 HydrophobicContact CB-CD1 4.27Å; L73-I459 HydrophobicContact CD2-CD1 4.32Å; W455-I459 HydrophobicContact CD2-CD1 3.64Å; W455-I459 HydrophobicContact CD2-CG1 4.44Å; W455-I459 HydrophobicContact CE3-CD1 3.69Å; W455-I459 HydrophobicContact CG-CD1 4.36Å; W455-I459 HydrophobicContact CH2-CD1 3.78Å; W455-I459 HydrophobicContact CZ2-CD1 3.75Å; W455-I459 HydrophobicContact CZ3-CD1 3.77Å; W455-I459 VanDerWaalsContact O-CG1 3.29Å; W455-I459 WeakPolarHBondContact O-CG1 3.5Å; W455-I459 PolarHBondContact O-N 3.35Å; T456-I459 PolarHBondContact O-N 3.3Å; I459-L462 PolarHBondContact O-N 3.03Å; I459-L463 PolarHBondContact O-N 2.88Å
460V91.5Very high87.1Confident77 Ų7745.9 Ų45.947%0.46725%0.248SC..Hα-helixtrans-64.5-45.1178.9173.30000111.1T456 C457 M458 L462 L463 L464T456-V460 WeakPolarHBondContact O-CG2 3.39Å; T456-V460 PolarHBondContact O-N 3.1Å; C457-V460 PolarHBondContact O-N 3.48Å; M458-V460 PolarHBondContact O-N 3.1Å; V460-L462 VanDerWaalsContact C-N 3.29Å; V460-L462 PolarHBondContact O-N 3.48Å; V460-L463 WeakPolarHBondContact O-CB 3.46Å; V460-L463 PolarHBondContact O-N 3.08Å; V460-L464 PolarHBondContact O-N 3.23Å; V460-L464 VanDerWaalsContact O-N 3.14Å
461T91.5Very high87.7Confident58 Ų5844 Ų4436%0.35624%0.24SC..Hα-helixtrans-60.6-41.7176.2-57.90000110.9F405 C457 M458 L463 L464 V465F405-T461 HydrophobicContact CE1-CG2 3.85Å; F405-T461 HydrophobicContact CZ-CG2 3.99Å; C457-T461 WeakPolarHBondContact O-CB 3.29Å; C457-T461 PolarHBondContact O-N 2.92Å; C457-T461 PolarHBondContact O-OG1 3Å; M458-T461 PolarHBondContact O-N 3.15Å; T461-L463 VanDerWaalsContact C-N 3.31Å; T461-L463 PolarHBondContact O-N 3.45Å; T461-L464 PolarHBondContact O-N 2.87Å; T461-V465 HydrophobicContact CG2-CG2 4.38Å; T461-V465 WeakPolarHBondContact O-CG2 3.13Å; T461-V465 PolarHBondContact O-N 3.42Å
462L90.2Very high88.4Confident0 Ų046.7 Ų46.70%025%0.254CS..Hα-helixtrans-62.2-40.1178.5-179.162.9000111.2V66 R69 V402 F405 Y406 M458 I459 V460 S466V66-L462 HydrophobicContact CG2-CB 4.34Å; V66-L462 HydrophobicContact CG2-CD2 4.12Å; V66-L462 HydrophobicContact CG2-CG 3.91Å; R69-L462 VanDerWaalsContact NH1-CD2 3.32Å; V402-L462 HydrophobicContact CG1-CD1 4.07Å; F405-L462 HydrophobicContact CB-CD1 4.34Å; F405-L462 HydrophobicContact CD1-CB 3.69Å; F405-L462 HydrophobicContact CD1-CD1 3.8Å; F405-L462 HydrophobicContact CD1-CG 4.28Å; F405-L462 HydrophobicContact CE1-CB 3.82Å; Y406-L462 HydrophobicContact CD2-CD2 4.14Å; M458-L462 WeakPolarHBondContact O-CB 3.47Å; M458-L462 PolarHBondContact O-N 3.29Å; I459-L462 PolarHBondContact O-N 3.03Å; V460-L462 VanDerWaalsContact C-N 3.29Å; V460-L462 PolarHBondContact O-N 3.48Å; L462-S466 WeakPolarHBondContact O-CB 3.39Å; L462-S466 PolarHBondContact O-N 2.83Å; L462-S466 PolarHBondContact O-OG 2.98Å
463L91.1Very high88.6Confident53 Ų5344.9 Ų44.928%0.27724%0.244SC..Hα-helixtrans-62.2-46.8177.5179.664.8000111.8V66 I459 V460 T461 S466 V467V66-L463 HydrophobicContact CB-CB 4.31Å; V66-L463 HydrophobicContact CB-CD1 4.15Å; V66-L463 HydrophobicContact CG1-CB 4.17Å; V66-L463 HydrophobicContact CG2-CB 3.96Å; V66-L463 HydrophobicContact CG2-CD1 4.15Å; I459-L463 PolarHBondContact O-N 2.88Å; V460-L463 WeakPolarHBondContact O-CB 3.46Å; V460-L463 PolarHBondContact O-N 3.08Å; T461-L463 VanDerWaalsContact C-N 3.31Å; T461-L463 PolarHBondContact O-N 3.45Å; L463-S466 PolarHBondContact O-OG 2.89Å; L463-S466 VanDerWaalsContact O-OG 3.1Å; L463-V467 HydrophobicContact CD1-CG2 4Å; L463-V467 WeakPolarHBondContact O-CB 3.49Å; L463-V467 VanDerWaalsContact O-CG2 3.24Å; L463-V467 WeakPolarHBondContact O-CG2 3.44Å; L463-V467 PolarHBondContact O-N 2.84Å
464L91.7Very high88.6Confident117 Ų11738.2 Ų38.261%0.61322%0.215SC*.Hα-helixtrans-63.7-47.1-179.2-66.7176.3000111V460 T461 L468V460-L464 PolarHBondContact O-N 3.23Å; V460-L464 VanDerWaalsContact O-N 3.14Å; T461-L464 PolarHBondContact O-N 2.87Å; L464-L468 VanDerWaalsContact O-CB 3.23Å; L464-L468 WeakPolarHBondContact O-CB 3.42Å; L464-L468 PolarHBondContact O-N 3.12Å
465V89.6Confident88.6Confident50 Ų5039.3 Ų39.330%0.30322%0.219SC..Hα-helixtrans-68.9-39.6-179.6-173.60000111M398 V402 T461 L468 Q469M398-V465 HydrophobicContact CE-CG1 3.98Å; M398-V465 WeakPolarHBondContact CE-O 3.43Å; V402-V465 HydrophobicContact CG2-CB 4.14Å; V402-V465 HydrophobicContact CG2-CG1 3.39Å; T461-V465 HydrophobicContact CG2-CG2 4.38Å; T461-V465 WeakPolarHBondContact O-CG2 3.13Å; T461-V465 PolarHBondContact O-N 3.42Å; V465-L468 PolarHBondContact O-N 2.9Å; V465-Q469 VanDerWaalsContact O-CB 3.24Å; V465-Q469 WeakPolarHBondContact O-CB 3.45Å; V465-Q469 PolarHBondContact O-N 2.95Å
466S86.9Confident88.7Confident2 Ų239.7 Ų39.71%0.01422%0.222CC..Hα-helixtrans-67.9-39.7179.870.10000112.8G62 L462 L463 A470G62-S466 WeakPolarHBondContact O-CB 3.46Å; G62-S466 PolarHBondContact O-OG 2.93Å; L462-S466 WeakPolarHBondContact O-CB 3.39Å; L462-S466 PolarHBondContact O-N 2.83Å; L462-S466 PolarHBondContact O-OG 2.98Å; L463-S466 PolarHBondContact O-OG 2.89Å; L463-S466 VanDerWaalsContact O-OG 3.1Å; S466-A470 WeakPolarHBondContact O-CB 3.48Å; S466-A470 PolarHBondContact O-N 3.43Å
467V89.8Confident88.5Confident26 Ų2637.5 Ų37.516%0.15821%0.209CC..Hα-helixtrans-68.4-46.4175.1171.80000110.5V59 L463 Q469 A470 I471V59-V467 HydrophobicContact CG2-CG1 4.2Å; L463-V467 HydrophobicContact CD1-CG2 4Å; L463-V467 WeakPolarHBondContact O-CB 3.49Å; L463-V467 VanDerWaalsContact O-CG2 3.24Å; L463-V467 WeakPolarHBondContact O-CG2 3.44Å; L463-V467 PolarHBondContact O-N 2.84Å; V467-Q469 VanDerWaalsContact C-N 3.3Å; V467-Q469 PolarHBondContact O-N 3.09Å; V467-A470 PolarHBondContact O-N 2.79Å; V467-I471 HydrophobicContact CG1-CD1 3.84Å; V467-I471 HydrophobicContact CG1-CG1 4.45Å; V467-I471 VanDerWaalsContact O-CG1 3.29Å; V467-I471 WeakPolarHBondContact O-CG1 3.35Å; V467-I471 PolarHBondContact O-N 3.22Å
468L90.6Very high88.3Confident92 Ų9233.8 Ų33.848%0.48218%0.183SC..Hα-helixtrans-58.7-44.1176.5-177.564000111.1M398 L464 V465 A470 I471 I472M398-L468 HydrophobicContact CE-CB 3.91Å; M398-L468 HydrophobicContact CE-CD2 3.88Å; M398-L468 HydrophobicContact CE-CG 3.79Å; L464-L468 VanDerWaalsContact O-CB 3.23Å; L464-L468 WeakPolarHBondContact O-CB 3.42Å; L464-L468 PolarHBondContact O-N 3.12Å; V465-L468 PolarHBondContact O-N 2.9Å; L468-A470 PolarHBondContact O-N 3.41Å; L468-I471 PolarHBondContact O-N 2.94Å; L468-I472 HydrophobicContact CD1-CD1 4.09Å; L468-I472 HydrophobicContact CD1-CG1 4.33Å; L468-I472 HydrophobicContact CG-CD1 3.88Å; L468-I472 HydrophobicContact CG-CG1 4.48Å; L468-I472 VanDerWaalsContact O-CG1 3.3Å; L468-I472 WeakPolarHBondContact O-CG1 3.25Å; L468-I472 PolarHBondContact O-N 3.22Å
469Q87.2Confident88.2Confident6 Ų639.9 Ų39.93%0.02821%0.205CC..Hα-helixtrans-59.9-47.2176.7-170.4-156.1-6.700111.6M398 V402 V465 V467 I471 I472 L473M398-Q469 HydrophobicContact CB-CG 4.38Å; M398-Q469 VanDerWaalsContact CE-CA 3.5Å; M398-Q469 HydrophobicContact CE-CB 3.65Å; M398-Q469 HydrophobicContact CE-CG 4.4Å; M398-Q469 VanDerWaalsContact CE-N 3.29Å; M398-Q469 HydrophobicContact CG-CB 4.1Å; M398-Q469 HydrophobicContact CG-CG 3.9Å; M398-Q469 VanDerWaalsContact SD-CA 3.57Å; M398-Q469 HydrophobicContact SD-CB 3.69Å; M398-Q469 HydrophobicContact SD-CG 3.79Å; V402-Q469 HydrophobicContact CG2-CB 4.37Å; V465-Q469 VanDerWaalsContact O-CB 3.24Å; V465-Q469 WeakPolarHBondContact O-CB 3.45Å; V465-Q469 PolarHBondContact O-N 2.95Å; V467-Q469 VanDerWaalsContact C-N 3.3Å; V467-Q469 PolarHBondContact O-N 3.09Å; Q469-I471 VanDerWaalsContact C-N 3.27Å; Q469-I471 PolarHBondContact O-N 2.89Å; Q469-I472 PolarHBondContact O-N 2.99Å; Q469-L473 WeakPolarHBondContact O-CB 3.36Å; Q469-L473 PolarHBondContact O-N 3.29Å
470A84.7Confident88Confident4 Ų439.7 Ų39.73%0.03321%0.205CC..Hα-helixtrans-61.7-38.3179.700000111.6A58 S466 V467 L468 R474A58-A470 HydrophobicContact CB-CB 4.17Å; A58-A470 WeakPolarHBondContact O-CB 3.48Å; S466-A470 WeakPolarHBondContact O-CB 3.48Å; S466-A470 PolarHBondContact O-N 3.43Å; V467-A470 PolarHBondContact O-N 2.79Å; L468-A470 PolarHBondContact O-N 3.41Å; A470-R474 WeakPolarHBondContact O-CB 3.44Å; A470-R474 PolarHBondContact O-N 2.97Å
471I89.3Confident87.8Confident40 Ų4036.1 Ų36.121%0.20518%0.183CC..Hα-helixtrans-63.3-56.5175-69.7170.3000110L55 A58 V467 L468 Q469 L473 R474 F475L55-I471 HydrophobicContact CD1-CD1 3.89Å; L55-I471 HydrophobicContact CD1-CG1 4.02Å; A58-I471 HydrophobicContact CB-CB 4.46Å; A58-I471 HydrophobicContact CB-CG1 3.79Å; V467-I471 HydrophobicContact CG1-CD1 3.84Å; V467-I471 HydrophobicContact CG1-CG1 4.45Å; V467-I471 VanDerWaalsContact O-CG1 3.29Å; V467-I471 WeakPolarHBondContact O-CG1 3.35Å; V467-I471 PolarHBondContact O-N 3.22Å; L468-I471 PolarHBondContact O-N 2.94Å; Q469-I471 VanDerWaalsContact C-N 3.27Å; Q469-I471 PolarHBondContact O-N 2.89Å; I471-L473 VanDerWaalsContact C-N 3.32Å; I471-L473 PolarHBondContact O-N 3.5Å; I471-R474 PolarHBondContact O-N 3.28Å; I471-R474 VanDerWaalsContact O-N 3.08Å; I471-F475 HydrophobicContact CG2-CD2 3.69Å; I471-F475 HydrophobicContact CG2-CE2 3.79Å; I471-F475 VanDerWaalsContact O-CD2 3.31Å; I471-F475 WeakPolarHBondContact O-CD2 3.27Å; I471-F475 PolarHBondContact O-N 3.43Å
472I88.1Confident87.7Confident67 Ų6735.6 Ų35.634%0.34418%0.176SC..Hα-helixtrans-58.9-44.2-176.4-61.1168.4000110.9L395 M398 L468 Q469 R474 S476L395-I472 HydrophobicContact CD2-CB 4.21Å; L395-I472 HydrophobicContact CD2-CG2 3.61Å; M398-I472 HydrophobicContact CE-CD1 4.32Å; M398-I472 HydrophobicContact SD-CD1 3.98Å; L468-I472 HydrophobicContact CD1-CD1 4.09Å; L468-I472 HydrophobicContact CD1-CG1 4.33Å; L468-I472 HydrophobicContact CG-CD1 3.88Å; L468-I472 HydrophobicContact CG-CG1 4.48Å; L468-I472 VanDerWaalsContact O-CG1 3.3Å; L468-I472 WeakPolarHBondContact O-CG1 3.25Å; L468-I472 PolarHBondContact O-N 3.22Å; Q469-I472 PolarHBondContact O-N 2.99Å; I472-R474 VanDerWaalsContact C-N 3.35Å; I472-R474 PolarHBondContact O-N 2.94Å; I472-S476 VanDerWaalsContact O-CB 3.26Å; I472-S476 WeakPolarHBondContact O-CB 3.25Å; I472-S476 PolarHBondContact O-N 3.4Å; I472-S476 PolarHBondContact O-OG 3.02Å
473L83.6Confident87.7Confident7 Ų739.5 Ų39.54%0.03719%0.191CC..Hα-helixtrans-59-47.2176.4179.563.3000111.2L395 Q469 I471 S476 L477 M526L395-L473 HydrophobicContact CD1-CD1 4.42Å; L395-L473 HydrophobicContact CD2-CB 4.26Å; L395-L473 HydrophobicContact CD2-CD1 4.5Å; Q469-L473 WeakPolarHBondContact O-CB 3.36Å; Q469-L473 PolarHBondContact O-N 3.29Å; I471-L473 VanDerWaalsContact C-N 3.32Å; I471-L473 PolarHBondContact O-N 3.5Å; L473-S476 WeakPolarHBondContact O-CB 3.48Å; L473-S476 PolarHBondContact O-N 3.46Å; L473-L477 HydrophobicContact CD1-CD1 4.2Å; L473-L477 HydrophobicContact CD1-CG 4.44Å; L473-L477 HydrophobicContact CG-CD1 4.06Å; L473-L477 WeakPolarHBondContact O-CG 3.44Å; L473-L477 PolarHBondContact O-N 2.86Å; L473-M526 HydrophobicContact CD1-CE 4.2Å; L473-M526 HydrophobicContact CD2-CB 4.09Å; L473-M526 HydrophobicContact CD2-CG 4.46Å
474R83.4Confident87.7Confident0 Ų037.2 Ų37.20%018%0.179CC..Hα-helixtrans-65.1-44.6-176.3-174.856.7155.5-165.227.6112.8A54 A58 A470 I471 I472 S476 L477 L478 T519 F520 N523A54-R474 HydrophobicContact CB-CG 3.41Å; A54-R474 VanDerWaalsContact CB-CG 3.41Å; A58-R474 HydrophobicContact CB-CB 4.28Å; A470-R474 WeakPolarHBondContact O-CB 3.44Å; A470-R474 PolarHBondContact O-N 2.97Å; I471-R474 PolarHBondContact O-N 3.28Å; I471-R474 VanDerWaalsContact O-N 3.08Å; I472-R474 VanDerWaalsContact C-N 3.35Å; I472-R474 PolarHBondContact O-N 2.94Å; R474-S476 VanDerWaalsContact C-N 3.31Å; R474-S476 PolarHBondContact O-N 2.91Å; R474-L477 PolarHBondContact O-N 2.75Å; R474-L478 WeakPolarHBondContact O-CG 3.2Å; R474-L478 PolarHBondContact O-N 3.48Å; R474-L478 VanDerWaalsContact O-N 3.12Å; R474-T519 VanDerWaalsContact NH1-C 3.32Å; R474-T519 PolarHBondContact NH1-O 3.12Å; R474-F520 VanDerWaalsContact NH2-CG 3.27Å; R474-N523 WeakPolarHBondContact CD-ND2 3.5Å; R474-N523 PolarHBondContact NH1-ND2 3.3Å
475F87.6Confident87.6Confident74 Ų7431.8 Ų31.833%0.32515%0.15SC..Hα-helixtrans-66.6-34.4176.7-82.8-84.5000112.1R51 I471 L478 R479R51-F475 HydrophobicContact CB-CE1 3.85Å; R51-F475 HydrophobicContact CB-CZ 4.35Å; R51-F475 HydrophobicContact CG-CD1 4.14Å; R51-F475 HydrophobicContact CG-CE1 3.63Å; I471-F475 HydrophobicContact CG2-CD2 3.69Å; I471-F475 HydrophobicContact CG2-CE2 3.79Å; I471-F475 VanDerWaalsContact O-CD2 3.31Å; I471-F475 WeakPolarHBondContact O-CD2 3.27Å; I471-F475 PolarHBondContact O-N 3.43Å; F475-L478 PolarHBondContact O-N 3.12Å; F475-R479 PolarHBondContact O-N 3.07Å
476S86.6Confident87.6Confident14 Ų1431.2 Ų31.210%0.09815%0.148CC..Hα-helixtrans-63.8-43.5175.9-65.40000112.4I472 L473 R474 R479 S480I472-S476 VanDerWaalsContact O-CB 3.26Å; I472-S476 WeakPolarHBondContact O-CB 3.25Å; I472-S476 PolarHBondContact O-N 3.4Å; I472-S476 PolarHBondContact O-OG 3.02Å; L473-S476 WeakPolarHBondContact O-CB 3.48Å; L473-S476 PolarHBondContact O-N 3.46Å; R474-S476 VanDerWaalsContact C-N 3.31Å; R474-S476 PolarHBondContact O-N 2.91Å; S476-R479 WeakPolarHBondContact O-CB 3.32Å; S476-R479 PolarHBondContact O-N 2.86Å; S476-S480 PolarHBondContact O-N 3.44Å; S476-S480 VanDerWaalsContact O-N 3.11Å
477L84.4Confident87.8Confident0 Ų036.5 Ų36.50%017%0.168CC..Hα-helixtrans-67.1-41.8176.8-65.4164.7000112.3Y382 L473 R474 R479 S480 A481 W522Y382-L477 HydrophobicContact CE1-CD2 3.78Å; L473-L477 HydrophobicContact CD1-CD1 4.2Å; L473-L477 HydrophobicContact CD1-CG 4.44Å; L473-L477 HydrophobicContact CG-CD1 4.06Å; L473-L477 WeakPolarHBondContact O-CG 3.44Å; L473-L477 PolarHBondContact O-N 2.86Å; R474-L477 PolarHBondContact O-N 2.75Å; L477-R479 VanDerWaalsContact C-N 3.25Å; L477-R479 PolarHBondContact O-N 3.17Å; L477-S480 PolarHBondContact O-N 2.85Å; L477-A481 PolarHBondContact O-N 3.15Å; L477-W522 HydrophobicContact CD1-CB 4.21Å; L477-W522 HydrophobicContact CD1-CG 4.17Å; L477-W522 HydrophobicContact CD2-CG 3.96Å
478L85.9Confident87.8Confident3 Ų335.4 Ų35.42%0.01616%0.161CC..Hα-helixtrans-60.2-36.5173.9-76179000112.2M47 L50 R51 A54 R474 F475 A481 F482 T519M47-L478 HydrophobicContact CE-CD2 4.4Å; M47-L478 HydrophobicContact SD-CB 3.83Å; M47-L478 HydrophobicContact SD-CD1 4.23Å; M47-L478 HydrophobicContact SD-CD2 3.95Å; M47-L478 HydrophobicContact SD-CG 4.23Å; L50-L478 HydrophobicContact CB-CD2 4.23Å; R51-L478 HydrophobicContact CG-CD1 4.06Å; A54-L478 HydrophobicContact CB-CD1 3.59Å; R474-L478 WeakPolarHBondContact O-CG 3.2Å; R474-L478 PolarHBondContact O-N 3.48Å; R474-L478 VanDerWaalsContact O-N 3.12Å; F475-L478 PolarHBondContact O-N 3.12Å; L478-A481 PolarHBondContact O-N 3.42Å; L478-F482 PolarHBondContact O-N 2.83Å; L478-T519 HydrophobicContact CD2-CG2 4.23Å
479R87.6Confident87.8Confident144 Ų14431.2 Ų31.254%0.54314%0.139SC..Hα-helixtrans-66.1-42.2175.6-171.7178.7-172.3167.93.5112.1F475 S476 L477 F482 R483F475-R479 PolarHBondContact O-N 3.07Å; S476-R479 WeakPolarHBondContact O-CB 3.32Å; S476-R479 PolarHBondContact O-N 2.86Å; L477-R479 VanDerWaalsContact C-N 3.25Å; L477-R479 PolarHBondContact O-N 3.17Å; R479-F482 PolarHBondContact O-N 2.88Å; R479-R483 VanDerWaalsContact NH2-NH2 3.13Å; R479-R483 PolarHBondContact O-N 3.1Å; R479-R483 VanDerWaalsContact O-N 3.1Å
480S87.6Confident88Confident0 Ų034 Ų340%015%0.152CC..Hα-helixtrans-60.3-48174.3177.80000111.1Y382 E385 S476 L477 F482 R483 L484Y382-S480 PolarHBondContact O-OG 2.97Å; E385-S480 WeakPolarHBondContact CB-OG 3.25Å; S476-S480 PolarHBondContact O-N 3.44Å; S476-S480 VanDerWaalsContact O-N 3.11Å; L477-S480 PolarHBondContact O-N 2.85Å; S480-F482 VanDerWaalsContact C-N 3.33Å; S480-F482 PolarHBondContact O-N 3.32Å; S480-R483 PolarHBondContact O-N 2.82Å; S480-R483 VanDerWaalsContact O-N 3.16Å; S480-L484 PolarHBondContact O-N 3.18Å
481A87.1Confident88.3Confident1 Ų135 Ų351%0.00816%0.156CC..Hα-helixtrans-60.2-37.5177.200000113.5L477 L478 H485 L515 T519L477-A481 PolarHBondContact O-N 3.15Å; L478-A481 PolarHBondContact O-N 3.42Å; A481-H485 WeakPolarHBondContact O-CB 3.23Å; A481-H485 PolarHBondContact O-N 3.37Å; A481-L515 HydrophobicContact CB-CD1 4.24Å; A481-L515 HydrophobicContact CB-CD2 4.39Å; A481-L515 HydrophobicContact CB-CG 4.02Å; A481-L515 WeakPolarHBondContact O-CD2 3.49Å; A481-T519 HydrophobicContact CB-CG2 3.72Å
482F89.2Confident88.4Confident47 Ų4733.1 Ų33.121%0.20615%0.146CC..Hα-helixtrans-65.2-44.6174.9-176.1-91.7000112.3R40 R43 M47 L478 R479 S480 S486R40-F482 HydrophobicContact CG-CZ 4.25Å; R43-F482 HydrophobicContact CB-CE2 4.27Å; R43-F482 HydrophobicContact CG-CD2 3.81Å; R43-F482 HydrophobicContact CG-CE2 3.84Å; M47-F482 HydrophobicContact CE-CB 4.11Å; M47-F482 HydrophobicContact CE-CD2 4.4Å; L478-F482 PolarHBondContact O-N 2.83Å; R479-F482 PolarHBondContact O-N 2.88Å; S480-F482 VanDerWaalsContact C-N 3.33Å; S480-F482 PolarHBondContact O-N 3.32Å; F482-S486 WeakPolarHBondContact O-CB 3.26Å; F482-S486 PolarHBondContact O-N 3.25Å; F482-S486 PolarHBondContact O-OG 3.28Å
483R89.9Confident88.5Confident83 Ų8330.4 Ų30.431%0.31313%0.132SC..Hα-helixtrans-68.1-45.6-178.5-78.5176.8168.7167.1-5.9112.4E385 I386 R479 S480 H485 S486 R487E385-R483 WeakPolarHBondContact O-CD 3.2Å; E385-R483 PolarHBondContact O-NH1 3.29Å; I386-R483 PolarHBondContact O-NH1 3.03Å; R479-R483 VanDerWaalsContact NH2-NH2 3.13Å; R479-R483 PolarHBondContact O-N 3.1Å; R479-R483 VanDerWaalsContact O-N 3.1Å; S480-R483 PolarHBondContact O-N 2.82Å; S480-R483 VanDerWaalsContact O-N 3.16Å; R483-H485 PolarHBondContact O-N 3.1Å; R483-S486 PolarHBondContact O-N 3.5Å; R483-R487 VanDerWaalsContact O-CB 3.28Å; R483-R487 WeakPolarHBondContact O-CB 3.42Å; R483-R487 PolarHBondContact O-N 3.06Å
484L90Very high88.9Confident5 Ų530.6 Ų30.63%0.02613%0.132CC..Hα-helixtrans-59.3-46.6176.6-79.6168.1000111.5Y382 E385 S480 R487 M488 L515 V613 I616 I617Y382-L484 HydrophobicContact CD2-CD1 3.41Å; Y382-L484 VanDerWaalsContact CD2-CD1 3.41Å; Y382-L484 HydrophobicContact CE2-CD1 3.89Å; Y382-L484 HydrophobicContact CG-CD1 4.46Å; E385-L484 HydrophobicContact CB-CG 4.27Å; E385-L484 HydrophobicContact CG-CD1 4.49Å; E385-L484 HydrophobicContact CG-CD2 3.83Å; E385-L484 HydrophobicContact CG-CG 3.91Å; S480-L484 PolarHBondContact O-N 3.18Å; L484-R487 PolarHBondContact O-N 2.99Å; L484-M488 VanDerWaalsContact O-CB 3.24Å; L484-M488 WeakPolarHBondContact O-CB 3.36Å; L484-M488 PolarHBondContact O-N 3.4Å; L484-L515 HydrophobicContact CB-CD2 4.11Å; L484-L515 HydrophobicContact CD1-CD1 4.32Å; L484-V613 HydrophobicContact CD1-CG1 4.38Å; L484-I616 HydrophobicContact CB-CG2 4.26Å; L484-I617 HydrophobicContact CD2-CG1 3.99Å
485H90.2Very high89.2Confident3 Ų330.7 Ų30.71%0.01413%0.133CC..Hα-helixtrans-60.4-48.3175.9178.1-93.2000112R12 A481 R483 R487 M488 F489 C512 L515R12-H485 PolarHBondContact NH1-NE2 3.42Å; A481-H485 WeakPolarHBondContact O-CB 3.23Å; A481-H485 PolarHBondContact O-N 3.37Å; R483-H485 PolarHBondContact O-N 3.1Å; H485-R487 VanDerWaalsContact C-N 3.34Å; H485-R487 PolarHBondContact O-N 3.33Å; H485-M488 WeakPolarHBondContact O-CE 3.37Å; H485-M488 PolarHBondContact O-N 3.34Å; H485-F489 WeakPolarHBondContact O-CB 3.43Å; H485-F489 PolarHBondContact O-N 3.16Å; H485-C512 VanDerWaalsContact CD2-SG 3.55Å; H485-L515 HydrophobicContact CB-CD2 4.14Å
486S89.8Confident89.2Confident37 Ų3729 Ų2926%0.25913%0.13SC..Hα-helixtrans-62.1-41.8179.8-570000112F482 R483 H490F482-S486 WeakPolarHBondContact O-CB 3.26Å; F482-S486 PolarHBondContact O-N 3.25Å; F482-S486 PolarHBondContact O-OG 3.28Å; R483-S486 PolarHBondContact O-N 3.5Å; S486-H490 WeakPolarHBondContact O-CB 3.47Å; S486-H490 PolarHBondContact O-N 3.06Å
487R90.4Very high89.1Confident114 Ų11428.7 Ų28.743%0.4313%0.127SC..Hα-helixtrans-66.1-47.3178.2-178.3179.5176.3167.43.4111.3E385 R483 L484 H485 H490 H491E385-R487 IonicContact OE1-NH1 2.77Å; E385-R487 PolarHBondContact OE1-NH1 3.47Å; E385-R487 VanDerWaalsContact OE1-NH1 3.13Å; R483-R487 VanDerWaalsContact O-CB 3.28Å; R483-R487 WeakPolarHBondContact O-CB 3.42Å; R483-R487 PolarHBondContact O-N 3.06Å; L484-R487 PolarHBondContact O-N 2.99Å; H485-R487 VanDerWaalsContact C-N 3.34Å; H485-R487 PolarHBondContact O-N 3.33Å; R487-H490 PolarHBondContact O-N 2.83Å; R487-H491 PolarHBondContact O-N 3.5Å; R487-H491 VanDerWaalsContact O-N 3.1Å; R487-H491 PolarHBondContact O-ND1 3.01Å
488M90.5Very high89Confident2 Ų229.7 Ų29.71%0.0113%0.134CC..Hα-helixtrans-60.1-48.9177.9172.5-84-41.400110.7L484 H485 H490 H491 V492 I508 C512 I616 Y619L484-M488 VanDerWaalsContact O-CB 3.24Å; L484-M488 WeakPolarHBondContact O-CB 3.36Å; L484-M488 PolarHBondContact O-N 3.4Å; H485-M488 WeakPolarHBondContact O-CE 3.37Å; H485-M488 PolarHBondContact O-N 3.34Å; M488-H490 VanDerWaalsContact C-N 3.32Å; M488-H490 PolarHBondContact O-N 2.95Å; M488-H491 PolarHBondContact O-N 3.25Å; M488-H491 VanDerWaalsContact O-N 3.08Å; M488-V492 HydrophobicContact CG-CG2 4.41Å; M488-V492 WeakPolarHBondContact O-CG2 3.42Å; M488-V492 PolarHBondContact O-N 3.26Å; M488-V492 HydrophobicContact SD-CG2 3.94Å; M488-I508 HydrophobicContact SD-CG2 4.05Å; M488-C512 WeakPolarHBondContact CE-SG 3.45Å; M488-I616 HydrophobicContact CB-CG2 3.77Å; M488-I616 HydrophobicContact CG-CG2 4Å; M488-Y619 HydrophobicContact CG-CD2 4.39Å
489F90.4Very high89Confident5 Ų530.7 Ų30.72%0.02214%0.138CC..Hα-helixtrans-61.7-40.3179.1-168.3-100.2000112.4M16 I19 M36 V39 H485 H491 V492 I493M16-F489 HydrophobicContact CE-CD2 3.85Å; M16-F489 HydrophobicContact CE-CE2 4.06Å; M16-F489 HydrophobicContact CG-CD2 4.48Å; M16-F489 HydrophobicContact CG-CE2 3.99Å; M16-F489 HydrophobicContact SD-CD2 4.35Å; M16-F489 HydrophobicContact SD-CE2 4.43Å; I19-F489 HydrophobicContact CD1-CZ 4.31Å; I19-F489 HydrophobicContact CG2-CZ 4.17Å; M36-F489 HydrophobicContact CB-CE1 4.46Å; M36-F489 HydrophobicContact CG-CD1 4.39Å; V39-F489 HydrophobicContact CB-CD1 4.25Å; V39-F489 HydrophobicContact CB-CE1 3.89Å; V39-F489 HydrophobicContact CB-CZ 4.08Å; V39-F489 HydrophobicContact CG1-CD1 4.13Å; V39-F489 HydrophobicContact CG1-CD2 4.27Å; V39-F489 HydrophobicContact CG1-CE1 4.16Å; V39-F489 HydrophobicContact CG1-CE2 4.28Å; V39-F489 HydrophobicContact CG1-CG 4.19Å; V39-F489 HydrophobicContact CG1-CZ 4.22Å; V39-F489 HydrophobicContact CG2-CE1 3.89Å; V39-F489 HydrophobicContact CG2-CE2 4.19Å; V39-F489 HydrophobicContact CG2-CZ 3.61Å; H485-F489 WeakPolarHBondContact O-CB 3.43Å; H485-F489 PolarHBondContact O-N 3.16Å; F489-H491 VanDerWaalsContact C-N 3.31Å; F489-H491 PolarHBondContact O-N 2.82Å; F489-V492 PolarHBondContact O-N 2.86Å; F489-I493 HydrophobicContact CE1-CD1 4.1Å; F489-I493 HydrophobicContact CZ-CD1 4.4Å; F489-I493 WeakPolarHBondContact O-CG2 3.49Å; F489-I493 PolarHBondContact O-N 2.82Å
490H90.8Very high88.7Confident65 Ų6525 Ų2530%0.30112%0.117SC..Hα-helixtrans-61.4-35.5174.9178.278.6000113.2M36 S486 R487 M488 I493 R494M36-H490 HydrophobicContact SD-CB 4.21Å; M36-H490 PolarHBondContact SD-ND1 3.33Å; S486-H490 WeakPolarHBondContact O-CB 3.47Å; S486-H490 PolarHBondContact O-N 3.06Å; R487-H490 PolarHBondContact O-N 2.83Å; M488-H490 VanDerWaalsContact C-N 3.32Å; M488-H490 PolarHBondContact O-N 2.95Å; H490-I493 WeakPolarHBondContact O-CG2 3.36Å; H490-R494 WeakPolarHBondContact O-CB 3.29Å; H490-R494 WeakPolarHBondContact O-CG 3.46Å; H490-R494 PolarHBondContact O-N 3.26Å
491H91.4Very high87.8Confident24 Ų2427.9 Ų27.911%0.11113%0.132CC..Hα-helixtrans-78.4-38.7176.7-71.169.6000111.6R487 M488 F489 R494 A495 Y619 G620 K624R487-H491 PolarHBondContact O-N 3.5Å; R487-H491 VanDerWaalsContact O-N 3.1Å; R487-H491 PolarHBondContact O-ND1 3.01Å; M488-H491 PolarHBondContact O-N 3.25Å; M488-H491 VanDerWaalsContact O-N 3.08Å; F489-H491 VanDerWaalsContact C-N 3.31Å; F489-H491 PolarHBondContact O-N 2.82Å; H491-R494 CarbonylContact O-C 3.57Å; H491-R494 PolarHBondContact O-N 2.87Å; H491-A495 PolarHBondContact O-N 2.92Å; H491-Y619 VanDerWaalsContact CB-O 3.27Å; H491-Y619 WeakPolarHBondContact CB-O 3.4Å; H491-G620 PolarHBondContact CD2-O 3.13Å; H491-G620 PolarHBondContact NE2-O 3.43Å; H491-K624 WeakPolarHBondContact CD2-CE 3.28Å; H491-K624 WeakPolarHBondContact NE2-CE 3.44Å; H491-K624 PolarHBondContact NE2-NZ 3.3Å
492V91.2Very high86.9Confident0 Ų035.2 Ų35.20%016%0.16CC..Hα-helixtrans-60.8-48.7176.2169.40000111.1L20 M488 F489 R494 A495 F499 F500 I508 L622L20-V492 HydrophobicContact CD2-CG1 3.73Å; M488-V492 HydrophobicContact CG-CG2 4.41Å; M488-V492 WeakPolarHBondContact O-CG2 3.42Å; M488-V492 PolarHBondContact O-N 3.26Å; M488-V492 HydrophobicContact SD-CG2 3.94Å; F489-V492 PolarHBondContact O-N 2.86Å; V492-R494 PolarHBondContact O-N 3Å; V492-A495 VanDerWaalsContact O-CB 3.3Å; V492-A495 WeakPolarHBondContact O-CB 3.46Å; V492-A495 PolarHBondContact O-N 3.14Å; V492-A495 VanDerWaalsContact O-N 3.07Å; V492-F499 HydrophobicContact CG1-CE1 4.08Å; V492-F499 HydrophobicContact CG2-CE1 4.44Å; V492-F500 HydrophobicContact CG1-CE1 4.1Å; V492-F500 HydrophobicContact CG1-CZ 4.29Å; V492-F500 WeakPolarHBondContact O-CZ 3.3Å; V492-I508 HydrophobicContact CG1-CD1 4.36Å; V492-L622 HydrophobicContact CG2-CD1 4.08Å
493I90.9Very high86Confident11 Ų1135.4 Ų35.46%0.05616%0.163CC..Hα-helixtrans-65.2-26.2179.5-157.6164.3000112.7I19 K27 E32 F35 F489 H490I19-I493 HydrophobicContact CG2-CD1 4.47Å; K27-I493 PolarHBondContact NZ-O 3.24Å; E32-I493 HydrophobicContact CB-CD1 4.05Å; E32-I493 HydrophobicContact CB-CG1 4.06Å; E32-I493 HydrophobicContact CG-CG1 4.08Å; E32-I493 WeakPolarHBondContact O-CD1 3.5Å; F35-I493 HydrophobicContact CB-CD1 4.43Å; F489-I493 HydrophobicContact CE1-CD1 4.1Å; F489-I493 HydrophobicContact CZ-CD1 4.4Å; F489-I493 WeakPolarHBondContact O-CG2 3.49Å; F489-I493 PolarHBondContact O-N 2.82Å; H490-I493 WeakPolarHBondContact O-CG2 3.36Å
494R91.5Very high84.9Confident11 Ų1134.3 Ų34.34%0.04217%0.167CC..Hα-helixtrans-89.5-5.4176.1-71-76.3-73.4135.91113.8H490 H491 V492 K624 E625 A626 E627 L628H490-R494 WeakPolarHBondContact O-CB 3.29Å; H490-R494 WeakPolarHBondContact O-CG 3.46Å; H490-R494 PolarHBondContact O-N 3.26Å; H491-R494 CarbonylContact O-C 3.57Å; H491-R494 PolarHBondContact O-N 2.87Å; V492-R494 PolarHBondContact O-N 3Å; R494-K624 HydrophobicContact CB-CB 4.44Å; R494-K624 HydrophobicContact CB-CG 4.28Å; R494-E625 PolarHBondContact NH2-O 3.19Å; R494-E625 PolarHBondContact O-N 2.8Å; R494-A626 PolarHBondContact NH1-O 3.32Å; R494-A626 VanDerWaalsContact NH1-O 3.1Å; R494-A626 PolarHBondContact NH2-O 3.49Å; R494-E627 IonicContact NH2-OE2 3.14Å; R494-L628 VanDerWaalsContact CZ-CD2 3.48Å; R494-L628 VanDerWaalsContact CZ-CG 3.4Å
495A90.7Very high84Confident1 Ų135.3 Ų35.31%0.00817%0.172CC..BIsolated β-bridgetrans-70.4153.9176.500000110.6K27 H491 V492 F499 L622 E625K27-A495 VanDerWaalsContact CE-O 3.28Å; K27-A495 WeakPolarHBondContact CE-O 3.34Å; K27-A495 PolarHBondContact NZ-O 2.78Å; H491-A495 PolarHBondContact O-N 2.92Å; V492-A495 VanDerWaalsContact O-CB 3.3Å; V492-A495 WeakPolarHBondContact O-CB 3.46Å; V492-A495 PolarHBondContact O-N 3.14Å; V492-A495 VanDerWaalsContact O-N 3.07Å; A495-F499 HydrophobicContact CB-CB 3.94Å; A495-F499 HydrophobicContact CB-CD1 3.98Å; A495-F499 HydrophobicContact CB-CG 3.98Å; A495-L622 HydrophobicContact CB-CD1 4.33Å; A495-E625 VanDerWaalsContact O-OE1 3.12Å
496S87.1Confident83Confident38 Ų3837.6 Ų37.627%0.26620%0.197SC..  trans-60153.3175.9176.80000111.7V498 F499 F500 E625 L694S496-V498 PolarHBondContact O-N 3.05Å; S496-V498 VanDerWaalsContact O-N 3.1Å; S496-F499 VanDerWaalsContact O-CB 3.27Å; S496-F499 WeakPolarHBondContact O-CB 3.34Å; S496-F499 PolarHBondContact O-N 3.47Å; S496-F500 WeakPolarHBondContact O-CD2 3.47Å; S496-E625 WeakPolarHBondContact CA-OE1 3.43Å; S496-L694 PolarHBondContact OG-O 3.28Å
497I85.4Confident82.2Confident8 Ų838.7 Ų38.74%0.04120%0.199CC..Hα-helixtrans-54.5-31.6177-165.959.6000113.2A23 R24 F499 F500 D501 L694 V695A23-I497 HydrophobicContact CB-CD1 4.43Å; R24-I497 HydrophobicContact CB-CD1 3.82Å; R24-I497 HydrophobicContact CG-CD1 4.42Å; I497-F499 PolarHBondContact O-N 2.75Å; I497-F499 VanDerWaalsContact O-N 3.16Å; I497-F500 HydrophobicContact CD1-CD2 4.3Å; I497-F500 PolarHBondContact O-N 3.01Å; I497-D501 PolarHBondContact O-N 3.03Å; I497-L694 HydrophobicContact CG2-CB 4.26Å; I497-V695 HydrophobicContact CG2-CG2 3.91Å
498V81.9Confident81.5Confident22 Ų2233.4 Ų33.413%0.13318%0.18CC..Hα-helixtrans-58.9-29.2177.3-177.70000112.2S496 R502 Y653 V695S496-V498 PolarHBondContact O-N 3.05Å; S496-V498 VanDerWaalsContact O-N 3.1Å; V498-R502 HydrophobicContact CG1-CG 4.46Å; V498-R502 VanDerWaalsContact O-CG 3.32Å; V498-R502 WeakPolarHBondContact O-CG 3.33Å; V498-R502 PolarHBondContact O-N 2.89Å; V498-Y653 HydrophobicContact CG2-CD1 3.96Å; V498-Y653 WeakPolarHBondContact CG2-O 3.28Å; V498-V695 HydrophobicContact CG2-CG2 3.99Å
499F84.6Confident80.7Confident24 Ų2434.3 Ų34.311%0.10519%0.185CC..Hα-helixtrans-64.3-42175.7171.4-97.8000111.8V492 A495 S496 I497 R502 N503 I508 Y619 L622V492-F499 HydrophobicContact CG1-CE1 4.08Å; V492-F499 HydrophobicContact CG2-CE1 4.44Å; A495-F499 HydrophobicContact CB-CB 3.94Å; A495-F499 HydrophobicContact CB-CD1 3.98Å; A495-F499 HydrophobicContact CB-CG 3.98Å; S496-F499 VanDerWaalsContact O-CB 3.27Å; S496-F499 WeakPolarHBondContact O-CB 3.34Å; S496-F499 PolarHBondContact O-N 3.47Å; I497-F499 PolarHBondContact O-N 2.75Å; I497-F499 VanDerWaalsContact O-N 3.16Å; F499-R502 PolarHBondContact O-N 3.42Å; F499-N503 VanDerWaalsContact CD2-ND2 3.27Å; F499-N503 WeakPolarHBondContact CD2-ND2 3.45Å; F499-N503 HydrophobicContact CE2-CB 4.22Å; F499-N503 VanDerWaalsContact CE2-ND2 3.33Å; F499-N503 WeakPolarHBondContact CE2-ND2 3.38Å; F499-N503 HydrophobicContact CZ-CB 4.19Å; F499-N503 WeakPolarHBondContact O-CB 3.46Å; F499-N503 PolarHBondContact O-N 3.29Å; F499-N503 PolarHBondContact O-ND2 3.48Å; F499-I508 HydrophobicContact CE1-CD1 3.87Å; F499-I508 HydrophobicContact CZ-CD1 3.97Å; F499-Y619 HydrophobicContact CE2-CD1 4.12Å; F499-Y619 AromaticContact CE2-CE1 3.94Å; F499-Y619 HydrophobicContact CE2-CE1 3.94Å; F499-Y619 AromaticContact CZ-CD1 3.98Å; F499-Y619 HydrophobicContact CZ-CD1 3.98Å; F499-Y619 AromaticContact CZ-CE1 3.85Å; F499-Y619 HydrophobicContact CZ-CE1 3.85Å; F499-L622 HydrophobicContact CD1-CD1 4.48Å; F499-L622 HydrophobicContact CD2-CD1 3.99Å; F499-L622 HydrophobicContact CD2-CD2 3.77Å; F499-L622 HydrophobicContact CE1-CD1 4.08Å; F499-L622 HydrophobicContact CE2-CD1 3.54Å; F499-L622 HydrophobicContact CE2-CD2 3.64Å; F499-L622 HydrophobicContact CE2-CG 4.25Å; F499-L622 HydrophobicContact CG-CD1 4.45Å; F499-L622 HydrophobicContact CZ-CD1 3.59Å
500F81.4Confident80.1Confident23 Ų2335.4 Ų35.410%0.10120%0.198CC..Hα-helixtrans-72.2-33.3-178.1-61.2-92.3000111.9L20 A23 V492 S496 I497 R502L20-F500 HydrophobicContact CD2-CD1 4.26Å; L20-F500 HydrophobicContact CD2-CE1 3.59Å; A23-F500 HydrophobicContact CB-CD1 3.74Å; A23-F500 HydrophobicContact CB-CD2 4.15Å; A23-F500 HydrophobicContact CB-CE1 3.71Å; A23-F500 HydrophobicContact CB-CE2 4.13Å; A23-F500 HydrophobicContact CB-CG 3.95Å; A23-F500 HydrophobicContact CB-CZ 3.9Å; V492-F500 HydrophobicContact CG1-CE1 4.1Å; V492-F500 HydrophobicContact CG1-CZ 4.29Å; V492-F500 WeakPolarHBondContact O-CZ 3.3Å; S496-F500 WeakPolarHBondContact O-CD2 3.47Å; I497-F500 HydrophobicContact CD1-CD2 4.3Å; I497-F500 PolarHBondContact O-N 3.01Å; F500-R502 VanDerWaalsContact C-N 3.3Å; F500-R502 PolarHBondContact O-N 3.49Å
501D69.4Low79.7Confident61 Ų6133.3 Ų33.333%0.32619%0.187SC..Hα-helixtrans-71.5-26.4176.2-64.9-30.5000112.3I497I497-D501 PolarHBondContact O-N 3.03Å
502R69.2Low79Confident156 Ų15632.2 Ų32.259%0.58918%0.182SC*.Hα-helixtrans-93.4-30.7-178-71.4179.6-179.7-161.2-4.4114.7V498 F499 F500 S654V498-R502 HydrophobicContact CG1-CG 4.46Å; V498-R502 VanDerWaalsContact O-CG 3.32Å; V498-R502 WeakPolarHBondContact O-CG 3.33Å; V498-R502 PolarHBondContact O-N 2.89Å; F499-R502 PolarHBondContact O-N 3.42Å; F500-R502 VanDerWaalsContact C-N 3.3Å; F500-R502 PolarHBondContact O-N 3.49Å; R502-S654 PolarHBondContact NH2-OG 3.34Å
503N70.4Confident78.3Confident50 Ų5035.5 Ų35.527%0.26720%0.199SC..SBendtrans-108.6117.8-172.9-67.9-94.4000110.3F499 I505F499-N503 VanDerWaalsContact CD2-ND2 3.27Å; F499-N503 WeakPolarHBondContact CD2-ND2 3.45Å; F499-N503 HydrophobicContact CE2-CB 4.22Å; F499-N503 VanDerWaalsContact CE2-ND2 3.33Å; F499-N503 WeakPolarHBondContact CE2-ND2 3.38Å; F499-N503 HydrophobicContact CZ-CB 4.19Å; F499-N503 WeakPolarHBondContact O-CB 3.46Å; F499-N503 PolarHBondContact O-N 3.29Å; F499-N503 PolarHBondContact O-ND2 3.48Å; N503-I505 PolarHBondContact O-N 3.31Å
504P66.7Low77.6Confident61 Ų6139.1 Ų39.140%0.39622%0.216SC..  trans-61.8127.3176.324.1-31.1000110.3G506 N507P504-G506 PolarHBondContact O-N 2.86Å; P504-G506 VanDerWaalsContact O-N 3.1Å; P504-N507 PolarHBondContact O-N 3.38Å
505I70.8Confident77.1Confident25 Ų2538.6 Ų38.613%0.12821%0.214CC..Hα-helixtrans-57.1-30.2-175.3-68165.5000112L20 N21 N503 N507 I508 V509L20-I505 HydrophobicContact CB-CB 4.47Å; L20-I505 HydrophobicContact CB-CD1 3.83Å; L20-I505 HydrophobicContact CB-CG1 3.92Å; L20-I505 HydrophobicContact CB-CG2 3.73Å; L20-I505 HydrophobicContact CD1-CG2 3.63Å; L20-I505 HydrophobicContact CG-CG2 4.31Å; N21-I505 WeakPolarHBondContact OD1-CD1 3.48Å; N503-I505 PolarHBondContact O-N 3.31Å; I505-N507 VanDerWaalsContact C-N 3.3Å; I505-N507 PolarHBondContact O-N 2.9Å; I505-I508 PolarHBondContact O-N 3.49Å; I505-V509 HydrophobicContact CG2-CG2 4.49Å; I505-V509 PolarHBondContact O-N 3.03Å
506G68.9Low76.2Confident52 Ų5239 Ų3954%0.53622%0.217SC..Hα-helixtrans-57.1-36179.300000114.3P504 V509 G510P504-G506 PolarHBondContact O-N 2.86Å; P504-G506 VanDerWaalsContact O-N 3.1Å; G506-V509 PolarHBondContact O-N 3.45Å; G506-G510 PolarHBondContact O-N 3.14Å
507N72.3Confident75.5Confident59 Ų5941.8 Ų41.832%0.31622%0.224SC..Hα-helixtrans-70.6-41.7-176.9-65.10.6000111.2E368 P504 I505 V509 G510 Y511E368-N507 PolarHBondContact OE1-ND2 3.38Å; P504-N507 PolarHBondContact O-N 3.38Å; I505-N507 VanDerWaalsContact C-N 3.3Å; I505-N507 PolarHBondContact O-N 2.9Å; N507-V509 VanDerWaalsContact C-N 3.29Å; N507-V509 PolarHBondContact O-N 2.98Å; N507-G510 PolarHBondContact O-N 3.5Å; N507-G510 VanDerWaalsContact O-N 3.16Å; N507-Y511 HydrophobicContact CB-CE2 4.23Å; N507-Y511 WeakPolarHBondContact O-CD2 3.4Å; N507-Y511 PolarHBondContact O-N 3.13Å
508I75.2Confident75Confident3 Ų341.4 Ų41.42%0.01522%0.222CC..Hα-helixtrans-59.4-43.5176.8-55.8177.7000110.4M488 V492 F499 I505 C512 Y619M488-I508 HydrophobicContact SD-CG2 4.05Å; V492-I508 HydrophobicContact CG1-CD1 4.36Å; F499-I508 HydrophobicContact CE1-CD1 3.87Å; F499-I508 HydrophobicContact CZ-CD1 3.97Å; I505-I508 PolarHBondContact O-N 3.49Å; I508-C512 PolarHBondContact O-N 3.25Å; I508-C512 PolarHBondContact O-SG 3.05Å; I508-Y619 HydrophobicContact CB-CE2 4.42Å; I508-Y619 HydrophobicContact CG1-CD2 4.43Å; I508-Y619 HydrophobicContact CG1-CE2 3.74Å
509V74.3Confident74.4Confident22 Ų2240.3 Ų40.313%0.13322%0.216CC..Hα-helixtrans-63.6-44.3177.1172.90000111I13 I505 G506 N507 C512 L513I13-V509 HydrophobicContact CB-CG1 4.32Å; I13-V509 HydrophobicContact CD1-CG1 4.33Å; I13-V509 HydrophobicContact CG1-CG1 4.04Å; I13-V509 HydrophobicContact CG2-CG1 3.46Å; I13-V509 VanDerWaalsContact CG2-CG1 3.46Å; I505-V509 HydrophobicContact CG2-CG2 4.49Å; I505-V509 PolarHBondContact O-N 3.03Å; G506-V509 PolarHBondContact O-N 3.45Å; N507-V509 VanDerWaalsContact C-N 3.29Å; N507-V509 PolarHBondContact O-N 2.98Å; V509-C512 WeakPolarHBondContact O-CB 3.26Å; V509-C512 PolarHBondContact O-N 3.19Å; V509-L513 PolarHBondContact O-N 3.39Å
510G77.9Confident73.6Confident27 Ų2740.3 Ų40.328%0.27822%0.216SC..Hα-helixtrans-59-46.5178.300000113.3G506 N507 C512 L513 H514G506-G510 PolarHBondContact O-N 3.14Å; N507-G510 PolarHBondContact O-N 3.5Å; N507-G510 VanDerWaalsContact O-N 3.16Å; G510-C512 VanDerWaalsContact C-N 3.3Å; G510-C512 PolarHBondContact O-N 3.08Å; G510-L513 WeakPolarHBondContact O-CB 3.47Å; G510-L513 PolarHBondContact O-N 3.14Å; G510-L513 VanDerWaalsContact O-N 3.1Å; G510-H514 PolarHBondContact O-N 3.06Å; G510-H514 VanDerWaalsContact O-N 3.15Å
511Y82Confident72.8Confident22 Ų2240 Ų409%0.08622%0.216CC..Hα-helixtrans-63-36.9179.1-55.9-43.2000112.6E368 N507 L513 H514 L515 R615 Y619E368-Y511 VanDerWaalsContact CD-OH 3.25Å; E368-Y511 PolarHBondContact OE1-OH 2.71Å; E368-Y511 PolarHBondContact OE2-OH 3.1Å; E368-Y511 VanDerWaalsContact OE2-OH 3.14Å; N507-Y511 HydrophobicContact CB-CE2 4.23Å; N507-Y511 WeakPolarHBondContact O-CD2 3.4Å; N507-Y511 PolarHBondContact O-N 3.13Å; Y511-L513 PolarHBondContact O-N 3.35Å; Y511-H514 PolarHBondContact O-N 3.07Å; Y511-L515 PolarHBondContact O-N 3.42Å; Y511-R615 HydrophobicContact CD1-CB 4.23Å; Y511-R615 HydrophobicContact CD1-CG 4.47Å; Y511-R615 HydrophobicContact CD2-CB 3.74Å; Y511-R615 HydrophobicContact CE1-CB 4.07Å; Y511-R615 HydrophobicContact CE1-CG 3.88Å; Y511-R615 HydrophobicContact CE2-CB 3.53Å; Y511-R615 HydrophobicContact CE2-CG 3.9Å; Y511-R615 HydrophobicContact CG-CB 4.08Å; Y511-Y619 HydrophobicContact CD2-CD2 4.41Å; Y511-Y619 AromaticContact CD2-CE2 3.67Å; Y511-Y619 HydrophobicContact CD2-CE2 3.67Å; Y511-Y619 AromaticContact CE2-CE2 3.69Å; Y511-Y619 HydrophobicContact CE2-CE2 3.69Å
512C77.1Confident72.6Confident1 Ų137.5 Ų37.51%0.00720%0.202CC..Hα-helixtrans-61.2-34.4176.3-660000112.6H485 M488 I508 V509 G510 S516H485-C512 VanDerWaalsContact CD2-SG 3.55Å; M488-C512 WeakPolarHBondContact CE-SG 3.45Å; I508-C512 PolarHBondContact O-N 3.25Å; I508-C512 PolarHBondContact O-SG 3.05Å; V509-C512 WeakPolarHBondContact O-CB 3.26Å; V509-C512 PolarHBondContact O-N 3.19Å; G510-C512 VanDerWaalsContact C-N 3.3Å; G510-C512 PolarHBondContact O-N 3.08Å; C512-S516 PolarHBondContact O-N 3.23Å; C512-S516 PolarHBondContact O-OG 3.44Å
513L76Confident72.1Confident68 Ų6830.2 Ų30.236%0.35618%0.175SC..Hα-helixtrans-67.8-48.4175.4-17267.7000110.2V509 G510 Y511 L515 S516 F517V509-L513 PolarHBondContact O-N 3.39Å; G510-L513 WeakPolarHBondContact O-CB 3.47Å; G510-L513 PolarHBondContact O-N 3.14Å; G510-L513 VanDerWaalsContact O-N 3.1Å; Y511-L513 PolarHBondContact O-N 3.35Å; L513-L515 VanDerWaalsContact C-N 3.33Å; L513-L515 PolarHBondContact O-N 2.94Å; L513-S516 WeakPolarHBondContact O-CB 3.19Å; L513-S516 PolarHBondContact O-N 3.04Å; L513-F517 HydrophobicContact CD1-CD2 4.38Å; L513-F517 HydrophobicContact CD1-CE2 3.82Å; L513-F517 HydrophobicContact CD2-CE2 4.19Å; L513-F517 HydrophobicContact CG-CD2 3.98Å; L513-F517 HydrophobicContact CG-CE2 3.68Å; L513-F517 VanDerWaalsContact O-CD2 3.31Å; L513-F517 WeakPolarHBondContact O-CD2 3.28Å; L513-F517 PolarHBondContact O-N 2.7Å; L513-F517 VanDerWaalsContact O-N 3.13Å
514H77.7Confident71.6Confident87 Ų8729 Ų2940%0.40317%0.167SC..Hα-helixtrans-60.2-38.6177.6-68.4-179.2000113.1G510 Y511 S516 F517 L518 S612G510-H514 PolarHBondContact O-N 3.06Å; G510-H514 VanDerWaalsContact O-N 3.15Å; Y511-H514 PolarHBondContact O-N 3.07Å; H514-S516 PolarHBondContact O-N 2.95Å; H514-F517 PolarHBondContact O-N 3.33Å; H514-F517 VanDerWaalsContact O-N 3.14Å; H514-L518 WeakPolarHBondContact O-CB 3.27Å; H514-L518 PolarHBondContact O-N 2.97Å; H514-S612 PolarHBondContact ND1-OG 3.03Å
515L79.4Confident71.2Confident0 Ų028.3 Ų28.30%016%0.157CC..Hα-helixtrans-58.8-36.1174.8-179.563.7000112.2Y382 A481 L484 H485 Y511 L513 L518 V613 I616Y382-L515 HydrophobicContact CE2-CD1 4.09Å; A481-L515 HydrophobicContact CB-CD1 4.24Å; A481-L515 HydrophobicContact CB-CD2 4.39Å; A481-L515 HydrophobicContact CB-CG 4.02Å; A481-L515 WeakPolarHBondContact O-CD2 3.49Å; L484-L515 HydrophobicContact CB-CD2 4.11Å; L484-L515 HydrophobicContact CD1-CD1 4.32Å; H485-L515 HydrophobicContact CB-CD2 4.14Å; Y511-L515 PolarHBondContact O-N 3.42Å; L513-L515 VanDerWaalsContact C-N 3.33Å; L513-L515 PolarHBondContact O-N 2.94Å; L515-L518 HydrophobicContact CD1-CD2 4.37Å; L515-V613 HydrophobicContact CD1-CG2 4.08Å; L515-I616 HydrophobicContact CB-CD1 3.66Å; L515-I616 HydrophobicContact CD1-CD1 4.46Å; L515-I616 HydrophobicContact CD2-CD1 3.8Å; L515-I616 HydrophobicContact CG-CD1 4.17Å
516S73.3Confident70.6Confident10 Ų1028.5 Ų28.57%0.0716%0.158CC..Hα-helixtrans-71.2-42.5177.2-540000110.5R43 C512 L513 H514 T519 F520R43-S516 PolarHBondContact NH1-OG 3.01Å; R43-S516 PolarHBondContact NH2-OG 3.34Å; R43-S516 VanDerWaalsContact NH2-OG 3.12Å; C512-S516 PolarHBondContact O-N 3.23Å; C512-S516 PolarHBondContact O-OG 3.44Å; L513-S516 WeakPolarHBondContact O-CB 3.19Å; L513-S516 PolarHBondContact O-N 3.04Å; H514-S516 PolarHBondContact O-N 2.95Å; S516-T519 PolarHBondContact O-N 3.3Å; S516-T519 PolarHBondContact O-OG1 3.38Å; S516-F520 VanDerWaalsContact O-CD2 3.27Å; S516-F520 WeakPolarHBondContact O-CD2 3.34Å; S516-F520 WeakPolarHBondContact O-CE2 3.47Å
517F72.6Confident70Confident96 Ų9626.8 Ų26.842%0.42114%0.135SC..Hα-helixtrans-64.6-39.3175.5-79.6-68.6000113.9L513 H514 T519 F520 S521L513-F517 HydrophobicContact CD1-CD2 4.38Å; L513-F517 HydrophobicContact CD1-CE2 3.82Å; L513-F517 HydrophobicContact CD2-CE2 4.19Å; L513-F517 HydrophobicContact CG-CD2 3.98Å; L513-F517 HydrophobicContact CG-CE2 3.68Å; L513-F517 VanDerWaalsContact O-CD2 3.31Å; L513-F517 WeakPolarHBondContact O-CD2 3.28Å; L513-F517 PolarHBondContact O-N 2.7Å; L513-F517 VanDerWaalsContact O-N 3.13Å; H514-F517 PolarHBondContact O-N 3.33Å; H514-F517 VanDerWaalsContact O-N 3.14Å; F517-T519 PolarHBondContact O-N 3.2Å; F517-T519 VanDerWaalsContact O-N 3.13Å; F517-F520 WeakPolarHBondContact O-CA 3.48Å; F517-F520 WeakPolarHBondContact O-CB 3.17Å; F517-F520 WeakPolarHBondContact O-CD2 3.45Å; F517-F520 PolarHBondContact O-N 2.71Å; F517-S521 PolarHBondContact O-N 2.88Å
518L74.4Confident69Low0 Ų024.2 Ų24.20%012%0.121CC..Hα-helixtrans-54.2-36.9178.317272.9000112.5Y382 H514 L515 F520 S521 W522 M609 M610 V613Y382-L518 HydrophobicContact CD2-CD2 4.34Å; Y382-L518 HydrophobicContact CE1-CD2 4.39Å; Y382-L518 HydrophobicContact CE2-CD2 3.72Å; H514-L518 WeakPolarHBondContact O-CB 3.27Å; H514-L518 PolarHBondContact O-N 2.97Å; L515-L518 HydrophobicContact CD1-CD2 4.37Å; L518-F520 PolarHBondContact O-N 3.04Å; L518-S521 PolarHBondContact O-N 2.88Å; L518-S521 VanDerWaalsContact O-N 3.15Å; L518-W522 HydrophobicContact CD1-CE3 4.39Å; L518-W522 WeakPolarHBondContact O-CB 3.39Å; L518-W522 PolarHBondContact O-N 3.28Å; L518-M609 HydrophobicContact CB-CB 4.41Å; L518-M609 HydrophobicContact CD1-CB 3.69Å; L518-M609 HydrophobicContact CD1-SD 4.48Å; L518-M610 HydrophobicContact CD1-CE 3.45Å; L518-M610 VanDerWaalsContact CD1-CE 3.45Å; L518-M610 HydrophobicContact CD2-CE 3.19Å; L518-M610 HydrophobicContact CG-CE 3.86Å; L518-V613 HydrophobicContact CD2-CG2 3.33Å
519T69.5Low67.9Low0 Ų025.3 Ų25.30%013%0.131CC..Hα-helixtrans-57.5-35.3178.767.80000110.9R474 L478 A481 S516 F517R474-T519 VanDerWaalsContact NH1-C 3.32Å; R474-T519 PolarHBondContact NH1-O 3.12Å; L478-T519 HydrophobicContact CD2-CG2 4.23Å; A481-T519 HydrophobicContact CB-CG2 3.72Å; S516-T519 PolarHBondContact O-N 3.3Å; S516-T519 PolarHBondContact O-OG1 3.38Å; F517-T519 PolarHBondContact O-N 3.2Å; F517-T519 VanDerWaalsContact O-N 3.13Å
520F68Low66.8Low24 Ų2425.7 Ų25.711%0.10513%0.13CC..Hα-helixtrans-63.7-53.9172.9-60.5-84.4000112.5W2 L50 H53 Q57 R474 S516 F517 L518 N523 Y524W2-F520 HydrophobicContact CH2-CE1 4.24Å; W2-F520 HydrophobicContact CH2-CE2 4.5Å; W2-F520 HydrophobicContact CH2-CZ 4Å; L50-F520 HydrophobicContact CD2-CE2 4.11Å; L50-F520 HydrophobicContact CD2-CZ 3.84Å; H53-F520 AromaticContact CD2-CE1 3.2Å; H53-F520 WeakPolarHBondContact CD2-CE1 3.28Å; H53-F520 AromaticContact CD2-CZ 3.54Å; H53-F520 AromaticContact NE2-CD1 4Å; H53-F520 AromaticContact NE2-CE1 3.17Å; H53-F520 WeakPolarHBondContact NE2-CE1 3.42Å; H53-F520 AromaticContact NE2-CZ 3.88Å; Q57-F520 VanDerWaalsContact OE1-CE1 3.23Å; R474-F520 VanDerWaalsContact NH2-CG 3.27Å; S516-F520 VanDerWaalsContact O-CD2 3.27Å; S516-F520 WeakPolarHBondContact O-CD2 3.34Å; S516-F520 WeakPolarHBondContact O-CE2 3.47Å; F517-F520 WeakPolarHBondContact O-CA 3.48Å; F517-F520 WeakPolarHBondContact O-CB 3.17Å; F517-F520 WeakPolarHBondContact O-CD2 3.45Å; F517-F520 PolarHBondContact O-N 2.71Å; L518-F520 PolarHBondContact O-N 3.04Å; F520-N523 PolarHBondContact O-N 3.22Å; F520-Y524 WeakPolarHBondContact O-CD2 3.3Å
521S64.6Low65.3Low15 Ų1525.2 Ų25.211%0.10512%0.124CC..Hα-helixtrans-70.6-33.5-174.9-53.40000113.5F517 L518 N523 Y524 Y525 M609F517-S521 PolarHBondContact O-N 2.88Å; L518-S521 PolarHBondContact O-N 2.88Å; L518-S521 VanDerWaalsContact O-N 3.15Å; S521-N523 PolarHBondContact O-N 3.03Å; S521-Y524 WeakPolarHBondContact O-CA 3.32Å; S521-Y524 VanDerWaalsContact O-CB 3.31Å; S521-Y524 WeakPolarHBondContact O-CB 3.37Å; S521-Y524 PolarHBondContact O-N 2.95Å; S521-Y525 PolarHBondContact O-N 2.89Å; S521-M609 WeakPolarHBondContact CB-SD 3.17Å; S521-M609 WeakPolarHBondContact OG-CE 3.3Å; S521-M609 PolarHBondContact OG-SD 2.95Å
522W63.5Low63.5Low9 Ų927.2 Ų27.23%0.03414%0.135CC..Hα-helixtrans-61.7-31.3-179.9-167.5-90.1000112.6Y379 Y382 L383 L477 L518 Y524 Y525 M526 V606 M610Y379-W522 AromaticContact CD1-CH2 3.81Å; Y379-W522 HydrophobicContact CD1-CH2 3.81Å; Y379-W522 AromaticContact CD1-CZ3 3.96Å; Y379-W522 HydrophobicContact CD1-CZ3 3.96Å; Y379-W522 HydrophobicContact CE1-CH2 4.29Å; Y379-W522 HydrophobicContact CE1-CZ3 4.08Å; Y382-W522 HydrophobicContact CE1-CD2 4.49Å; L383-W522 HydrophobicContact CD2-CZ2 4.25Å; L477-W522 HydrophobicContact CD1-CB 4.21Å; L477-W522 HydrophobicContact CD1-CG 4.17Å; L477-W522 HydrophobicContact CD2-CG 3.96Å; L518-W522 HydrophobicContact CD1-CE3 4.39Å; L518-W522 WeakPolarHBondContact O-CB 3.39Å; L518-W522 PolarHBondContact O-N 3.28Å; W522-Y524 VanDerWaalsContact C-N 3.27Å; W522-Y524 PolarHBondContact O-N 2.93Å; W522-Y525 HydrophobicContact CH2-CD1 4.19Å; W522-Y525 HydrophobicContact CH2-CE1 4.22Å; W522-Y525 HydrophobicContact CZ2-CD1 4.34Å; W522-Y525 HydrophobicContact CZ3-CD1 4.31Å; W522-Y525 PolarHBondContact O-N 2.98Å; W522-M526 VanDerWaalsContact CD1-CG 3.4Å; W522-M526 HydrophobicContact CG-CG 4.35Å; W522-M526 HydrophobicContact CZ2-SD 4.31Å; W522-M526 WeakPolarHBondContact O-CB 3.27Å; W522-M526 WeakPolarHBondContact O-CG 3.48Å; W522-M526 PolarHBondContact O-N 2.75Å; W522-V606 HydrophobicContact CE3-CG1 3.55Å; W522-V606 HydrophobicContact CE3-CG2 4.22Å; W522-V606 HydrophobicContact CH2-CG1 4.42Å; W522-V606 HydrophobicContact CZ3-CG1 3.32Å; W522-M610 HydrophobicContact CE3-CE 4.08Å; W522-M610 HydrophobicContact CZ3-CE 3.99Å; W522-M610 HydrophobicContact CZ3-SD 4.43Å
523N60.5Low62.2Low3 Ų334.2 Ų34.22%0.01617%0.166CC..Hα-helixtrans-62.8-35.8174-95.9-2.3000112.3I61 R474 F520 S521 R527I61-N523 HydrophobicContact CD1-CB 4.07Å; R474-N523 WeakPolarHBondContact CD-ND2 3.5Å; R474-N523 PolarHBondContact NH1-ND2 3.3Å; F520-N523 PolarHBondContact O-N 3.22Å; S521-N523 PolarHBondContact O-N 3.03Å; N523-R527 WeakPolarHBondContact O-CB 3.28Å; N523-R527 PolarHBondContact O-N 3.45Å
524Y59.7Low60.8Low26 Ų2635.2 Ų35.210%0.10217%0.165CC..Hα-helixtrans-69.8-46.1174.2-72.5-74.8000111.6L107 F111 F520 S521 W522 R527 S528 F598L107-Y524 HydrophobicContact CD1-CE1 4.17Å; F111-Y524 HydrophobicContact CE2-CE1 4.41Å; F111-Y524 AromaticContact CE2-CZ 3.83Å; F111-Y524 WeakPolarHBondContact CE2-OH 3.43Å; F111-Y524 HydrophobicContact CZ-CE2 4.25Å; F111-Y524 AromaticContact CZ-CZ 3.64Å; F111-Y524 WeakPolarHBondContact CZ-OH 3.2Å; F520-Y524 WeakPolarHBondContact O-CD2 3.3Å; S521-Y524 WeakPolarHBondContact O-CA 3.32Å; S521-Y524 VanDerWaalsContact O-CB 3.31Å; S521-Y524 WeakPolarHBondContact O-CB 3.37Å; S521-Y524 PolarHBondContact O-N 2.95Å; W522-Y524 VanDerWaalsContact C-N 3.27Å; W522-Y524 PolarHBondContact O-N 2.93Å; Y524-R527 WeakPolarHBondContact O-CB 3.18Å; Y524-R527 PolarHBondContact O-N 2.74Å; Y524-S528 WeakPolarHBondContact O-CB 3.18Å; Y524-S528 PolarHBondContact O-N 2.96Å; Y524-S528 PolarHBondContact O-OG 2.72Å; Y524-F598 HydrophobicContact CD1-CZ 4.06Å
525Y58.2Low59.2Low45 Ų4535.3 Ų35.318%0.17617%0.168CC..Hα-helixtrans-62.4-46177.1179.7-97.6000112.3S521 W522 R527 S528 A529 M599 V606S521-Y525 PolarHBondContact O-N 2.89Å; W522-Y525 HydrophobicContact CH2-CD1 4.19Å; W522-Y525 HydrophobicContact CH2-CE1 4.22Å; W522-Y525 HydrophobicContact CZ2-CD1 4.34Å; W522-Y525 HydrophobicContact CZ3-CD1 4.31Å; W522-Y525 PolarHBondContact O-N 2.98Å; Y525-R527 VanDerWaalsContact C-N 3.27Å; Y525-R527 PolarHBondContact O-N 2.84Å; Y525-S528 CarbonylContact O-C 3.59Å; Y525-S528 WeakPolarHBondContact O-CA 3.46Å; Y525-S528 WeakPolarHBondContact O-CB 3.33Å; Y525-S528 PolarHBondContact O-N 3.39Å; Y525-A529 HydrophobicContact CE1-CB 4.24Å; Y525-A529 WeakPolarHBondContact O-CB 3.27Å; Y525-A529 PolarHBondContact O-N 3.14Å; Y525-M599 HydrophobicContact CE2-CE 4.39Å; Y525-V606 HydrophobicContact CD1-CG1 4.46Å; Y525-V606 HydrophobicContact CD2-CB 4.16Å; Y525-V606 HydrophobicContact CD2-CG1 4.47Å; Y525-V606 HydrophobicContact CD2-CG2 4.25Å; Y525-V606 HydrophobicContact CG-CB 4.15Å; Y525-V606 HydrophobicContact CG-CG1 4.26Å; Y525-V606 HydrophobicContact CG-CG2 3.87Å
526M58.3Low57.6Low30 Ų3043.5 Ų43.515%0.14821%0.206CC..Hα-helixtrans-64.1-32.9175.1-74.2-70.8-81.100112L473 W522 S528 R530L473-M526 HydrophobicContact CD1-CE 4.2Å; L473-M526 HydrophobicContact CD2-CB 4.09Å; L473-M526 HydrophobicContact CD2-CG 4.46Å; W522-M526 VanDerWaalsContact CD1-CG 3.4Å; W522-M526 HydrophobicContact CG-CG 4.35Å; W522-M526 HydrophobicContact CZ2-SD 4.31Å; W522-M526 WeakPolarHBondContact O-CB 3.27Å; W522-M526 WeakPolarHBondContact O-CG 3.48Å; W522-M526 PolarHBondContact O-N 2.75Å; M526-S528 VanDerWaalsContact C-N 3.34Å; M526-R530 VanDerWaalsContact O-CB 3.3Å; M526-R530 WeakPolarHBondContact O-CB 3.47Å; M526-R530 WeakPolarHBondContact O-CG 3.39Å; M526-R530 PolarHBondContact O-N 3.02Å; M526-R530 VanDerWaalsContact O-N 3.11Å; M526-R530 PolarHBondContact O-NE 2.6Å
527R55.4Low56Low16 Ų1647 Ų476%0.0624%0.235CC..Hα-helixtrans-63.8-41.3171.5165.2176.5160.1165.1-8.4111.4Y64 L107 N523 Y524 Y525Y64-R527 VanDerWaalsContact CD1-CZ 3.43Å; Y64-R527 PolarHBondContact OH-NH2 3.42Å; L107-R527 VanDerWaalsContact CD1-NH1 3.34Å; N523-R527 WeakPolarHBondContact O-CB 3.28Å; N523-R527 PolarHBondContact O-N 3.45Å; Y524-R527 WeakPolarHBondContact O-CB 3.18Å; Y524-R527 PolarHBondContact O-N 2.74Å; Y525-R527 VanDerWaalsContact C-N 3.27Å; Y525-R527 PolarHBondContact O-N 2.84Å
528S51.9Low54.6Low4 Ų445.6 Ų45.63%0.02824%0.242CC..Hα-helixtrans-69.7-55.6177.1-63.50000110.5Y524 Y525 M526 R530 A531 L532 F598 M599Y524-S528 WeakPolarHBondContact O-CB 3.18Å; Y524-S528 PolarHBondContact O-N 2.96Å; Y524-S528 PolarHBondContact O-OG 2.72Å; Y525-S528 CarbonylContact O-C 3.59Å; Y525-S528 WeakPolarHBondContact O-CA 3.46Å; Y525-S528 WeakPolarHBondContact O-CB 3.33Å; Y525-S528 PolarHBondContact O-N 3.39Å; M526-S528 VanDerWaalsContact C-N 3.34Å; S528-R530 PolarHBondContact O-N 3.06Å; S528-R530 VanDerWaalsContact O-N 3.13Å; S528-A531 WeakPolarHBondContact O-CA 3.38Å; S528-A531 VanDerWaalsContact O-CB 3.25Å; S528-A531 WeakPolarHBondContact O-CB 3.32Å; S528-A531 PolarHBondContact O-N 2.94Å; S528-L532 PolarHBondContact O-N 3.21Å; S528-F598 VanDerWaalsContact OG-CD1 3.24Å; S528-F598 WeakPolarHBondContact OG-CD1 3.29Å; S528-F598 WeakPolarHBondContact OG-CE1 3.32Å; S528-M599 VanDerWaalsContact CB-CE 3.41Å; S528-M599 WeakPolarHBondContact CB-SD 3.35Å
529A51.4Low53.4Low27 Ų2748.4 Ų48.422%0.22326%0.258CS..Hα-helixtrans-58.1-29.9-178.800000113.1Y525 A531 L532 M599Y525-A529 HydrophobicContact CE1-CB 4.24Å; Y525-A529 WeakPolarHBondContact O-CB 3.27Å; Y525-A529 PolarHBondContact O-N 3.14Å; A529-A531 PolarHBondContact O-N 3.45Å; A529-L532 WeakPolarHBondContact O-CB 3.34Å; A529-L532 PolarHBondContact O-N 3.01Å; A529-M599 HydrophobicContact CB-CE 4.47Å; A529-M599 PolarHBondContact N-SD 3.15Å; A529-M599 VanDerWaalsContact N-SD 3.4Å
530R51.3Low52.1Low30 Ų3053.7 Ų53.711%0.11328%0.279CS..Hα-helixtrans-56.9-33.1169.4-86.4179.5-82.3175.8-5.4113.1A399 M526 S528A399-R530 HydrophobicContact CB-CG 4.17Å; M526-R530 VanDerWaalsContact O-CB 3.3Å; M526-R530 WeakPolarHBondContact O-CB 3.47Å; M526-R530 WeakPolarHBondContact O-CG 3.39Å; M526-R530 PolarHBondContact O-N 3.02Å; M526-R530 VanDerWaalsContact O-N 3.11Å; M526-R530 PolarHBondContact O-NE 2.6Å; S528-R530 PolarHBondContact O-N 3.06Å; S528-R530 VanDerWaalsContact O-N 3.13Å
531A46.4Very low51Low17 Ų1759.2 Ų59.214%0.1431%0.309CS..Hα-helixtrans-79.3-19.8174.900000113.2S528 A529 R534S528-A531 WeakPolarHBondContact O-CA 3.38Å; S528-A531 VanDerWaalsContact O-CB 3.25Å; S528-A531 WeakPolarHBondContact O-CB 3.32Å; S528-A531 PolarHBondContact O-N 2.94Å; A529-A531 PolarHBondContact O-N 3.45Å; A531-R534 WeakPolarHBondContact O-CB 3.36Å; A531-R534 VanDerWaalsContact O-CD 3.31Å; A531-R534 WeakPolarHBondContact O-CD 3.46Å; A531-R534 WeakPolarHBondContact O-CG 3.25Å; A531-R534 PolarHBondContact O-N 3.43Å
532L43.6Very low50.2Low64 Ų6465.1 Ų65.134%0.33534%0.339SS..Hα-helixtrans-75.2-23.5-177.9-160.979000113.4S528 A529 R534 L535 Y540 M599S528-L532 PolarHBondContact O-N 3.21Å; A529-L532 WeakPolarHBondContact O-CB 3.34Å; A529-L532 PolarHBondContact O-N 3.01Å; L532-R534 PolarHBondContact O-N 3.42Å; L532-L535 PolarHBondContact O-N 2.85Å; L532-Y540 HydrophobicContact CD1-CD2 4.41Å; L532-Y540 HydrophobicContact CD2-CD2 3.83Å; L532-Y540 HydrophobicContact CD2-CE2 3.65Å; L532-M599 HydrophobicContact CB-SD 4.1Å; L532-M599 HydrophobicContact CD1-SD 4.26Å
533K51.4Low49.4Very low148 Ų14867 Ų6764%0.64335%0.35SS*.THydrogen-bonded Turntrans-63.33.4170-76-168.2175.6-172.10114L400L400-K533 HydrophobicContact CD2-CD 3.68Å
534R45.5Very low48.8Very low88 Ų8874 Ų7433%0.33238%0.382SS..THydrogen-bonded Turntrans-80.1-12.4174.6-70.3177.5175.7174.9-3114.7Q403 A531 L532Q403-R534 VanDerWaalsContact NE2-NH2 3.1Å; A531-R534 WeakPolarHBondContact O-CB 3.36Å; A531-R534 VanDerWaalsContact O-CD 3.31Å; A531-R534 WeakPolarHBondContact O-CD 3.46Å; A531-R534 WeakPolarHBondContact O-CG 3.25Å; A531-R534 PolarHBondContact O-N 3.43Å; L532-R534 PolarHBondContact O-N 3.42Å
535L45.3Very low48Very low90 Ų9078.9 Ų78.947%0.47141%0.414SS..SBendtrans-145.5133.4-173.9-92.7142.8000112.1L532 V539 L592L532-L535 PolarHBondContact O-N 2.85Å; L535-V539 HydrophobicContact CD2-CG2 4.2Å; L535-L592 HydrophobicContact CD1-CD1 3.91Å; L535-L592 HydrophobicContact CD1-CD2 3.7Å; L535-L592 HydrophobicContact CD1-CG 4.45Å
536E44.5Very low47.1Very low172 Ų17279.6 Ų79.680%0.80443%0.426SS*.  trans-51.6152.2174-70.6179.4142.800112.7A538 V539E536-A538 PolarHBondContact O-N 3.38Å; E536-V539 PolarHBondContact O-N 2.77Å
537A39.9Very low46.7Very low82 Ų8285.5 Ų85.568%0.67846%0.463SS*.THydrogen-bonded Turntrans-49.8-10-175.300000116.7L541A537-L541 PolarHBondContact O-N 3.3Å
538A42.5Very low46.3Very low68 Ų6889.6 Ų89.656%0.56249%0.486SS*.Hα-helixtrans-70.5-32.4-177.700000114.4E536E536-A538 PolarHBondContact O-N 3.38Å
539V49Very low46.2Very low58 Ų5894 Ų9435%0.35251%0.514SS..Hα-helixtrans-79-30.1178.5177.10000111.7L535 E536 L542 L543L535-V539 HydrophobicContact CD2-CG2 4.2Å; E536-V539 PolarHBondContact O-N 2.77Å; V539-L542 PolarHBondContact O-N 3.34Å; V539-L543 HydrophobicContact CG1-CD1 3.63Å; V539-L543 HydrophobicContact CG1-CG 4.5Å; V539-L543 WeakPolarHBondContact O-CD1 3.32Å; V539-L543 WeakPolarHBondContact O-CG 3.25Å; V539-L543 PolarHBondContact O-N 3.32Å
540Y44.3Very low46.1Very low112 Ų11295.1 Ų95.144%0.43953%0.529SS..Hα-helixtrans-68.3-36.2178.4-156.7-96.1000112L532 L543L532-Y540 HydrophobicContact CD1-CD2 4.41Å; L532-Y540 HydrophobicContact CD2-CD2 3.83Å; L532-Y540 HydrophobicContact CD2-CE2 3.65Å; Y540-L543 PolarHBondContact O-N 3.1Å
541L44.2Very low46.1Very low139 Ų13997 Ų9773%0.72855%0.551SS**Hα-helixtrans-73.2-28.4177.9-131.6143000112.8A537A537-L541 PolarHBondContact O-N 3.3Å
542L47.3Very low46.3Very low140 Ų140102.2 Ų102.273%0.73357%0.568SS**Hα-helixtrans-79.9-22175.1-92.6154.3000113.8V539V539-L542 PolarHBondContact O-N 3.34Å
543L46.9Very low46.5Very low49 Ų49100.8 Ų100.826%0.25756%0.56SS.*Hα-helixtrans-92.9-21.2-174.8-84.2162.2000114.7V539 Y540 V545 L553V539-L543 HydrophobicContact CG1-CD1 3.63Å; V539-L543 HydrophobicContact CG1-CG 4.5Å; V539-L543 WeakPolarHBondContact O-CD1 3.32Å; V539-L543 WeakPolarHBondContact O-CG 3.25Å; V539-L543 PolarHBondContact O-N 3.32Å; Y540-L543 PolarHBondContact O-N 3.1Å; L543-V545 PolarHBondContact O-N 3.22Å; L543-V545 VanDerWaalsContact O-N 3.08Å; L543-L553 HydrophobicContact CD2-CD1 4.36Å
544Q47.1Very low46.5Very low150 Ų15096 Ų9670%0.70155%0.548SS*.THydrogen-bonded Turntrans-68.7-2.4178-75.9-161.6-34.300114.3
545V44.4Very low46.9Very low127 Ų127100.1 Ų100.177%0.7756%0.564SS**THydrogen-bonded Turntrans-92.13-177.1179.40000114L543L543-V545 PolarHBondContact O-N 3.22Å; L543-V545 VanDerWaalsContact O-N 3.08Å
546S39.1Very low47.4Very low60 Ų6098.9 Ų98.942%0.4256%0.559SS.*  trans-133.186.5-172.753.70000116.4L548S546-L548 PolarHBondContact O-N 3.37Å
547V49.2Very low47.9Very low154 Ų15492.8 Ų92.893%0.93353%0.532SS*.  trans-72.863.3157-175.20000109.2
548L47.8Very low48.6Very low102 Ų10291.8 Ų91.853%0.53452%0.524SS..  trans-131.8144.7178.5-81.4167.8000112.2S546 Y552S546-L548 PolarHBondContact O-N 3.37Å; L548-Y552 HydrophobicContact CD1-CD1 4.06Å; L548-Y552 HydrophobicContact CD1-CE1 4.3Å
549P49Very low49.2Very low96 Ų9697.3 Ų97.362%0.62353%0.53SS*.  trans-56.9142.2-173.7-19.629.7000112A551 Y552P549-A551 PolarHBondContact O-N 3.1Å; P549-Y552 PolarHBondContact O-N 3.07Å
550G48.7Very low49.6Very low52 Ų5299.3 Ų99.354%0.53654%0.538SS..Hα-helixtrans-51.6-17.2-172.700000117A554G550-A554 PolarHBondContact O-N 2.95Å
551A51.1Low50.1Low69 Ų6998.3 Ų98.357%0.5754%0.543SS*.Hα-helixtrans-66.1-34.7170.600000113.3P549 R555P549-A551 PolarHBondContact O-N 3.1Å; A551-R555 PolarHBondContact O-N 3.48Å
552Y51.9Low50.6Low127 Ų12797.4 Ų97.450%0.49854%0.539SS..Hα-helixtrans-72.9-40.9176.3-152.9-96.5000110.7L548 P549 A554 R555 V556L548-Y552 HydrophobicContact CD1-CD1 4.06Å; L548-Y552 HydrophobicContact CD1-CE1 4.3Å; P549-Y552 PolarHBondContact O-N 3.07Å; Y552-A554 VanDerWaalsContact C-N 3.34Å; Y552-A554 PolarHBondContact O-N 3.15Å; Y552-R555 PolarHBondContact O-N 3.16Å; Y552-R555 VanDerWaalsContact O-N 3.16Å; Y552-V556 HydrophobicContact CD1-CG2 3.88Å; Y552-V556 HydrophobicContact CE1-CG2 3.94Å; Y552-V556 WeakPolarHBondContact O-CG2 3.17Å; Y552-V556 PolarHBondContact O-N 2.96Å
553L48.2Very low51.1Low34 Ų3495 Ų9518%0.17853%0.531CS..Hα-helixtrans-60.1-42173.9-162.383.3000111.5L543 R555 V556 L557 Q597 L600L543-L553 HydrophobicContact CD2-CD1 4.36Å; L553-R555 PolarHBondContact O-N 2.82Å; L553-V556 PolarHBondContact O-N 2.89Å; L553-L557 HydrophobicContact CD2-CD1 4.07Å; L553-L557 HydrophobicContact CG-CD1 3.9Å; L553-L557 HydrophobicContact CG-CG 4.39Å; L553-L557 VanDerWaalsContact O-CB 3.27Å; L553-L557 WeakPolarHBondContact O-CB 3.31Å; L553-L557 WeakPolarHBondContact O-CD1 3.34Å; L553-L557 WeakPolarHBondContact O-CG 3.2Å; L553-L557 PolarHBondContact O-N 3.03Å; L553-Q597 HydrophobicContact CD2-CG 4.3Å; L553-L600 HydrophobicContact CD2-CD1 4.29Å
554A50.5Low51.6Low47 Ų4797.6 Ų97.639%0.38854%0.541SS..Hα-helixtrans-62.5-39.3174.800000112.6G550 Y552 A558G550-A554 PolarHBondContact O-N 2.95Å; Y552-A554 VanDerWaalsContact C-N 3.34Å; Y552-A554 PolarHBondContact O-N 3.15Å; A554-A558 VanDerWaalsContact O-CB 3.24Å; A554-A558 WeakPolarHBondContact O-CB 3.42Å; A554-A558 PolarHBondContact O-N 3.02Å
555R53.4Low52Low175 Ų17598.2 Ų98.266%0.6654%0.541SS*.Hα-helixtrans-68.6-38.4175-75.3178.9179160.50.5112.8A551 Y552 L553 R559A551-R555 PolarHBondContact O-N 3.48Å; Y552-R555 PolarHBondContact O-N 3.16Å; Y552-R555 VanDerWaalsContact O-N 3.16Å; L553-R555 PolarHBondContact O-N 2.82Å; R555-R559 WeakPolarHBondContact O-CG 3.04Å; R555-R559 PolarHBondContact O-N 3.37Å; R555-R559 VanDerWaalsContact O-N 3.1Å
556V57.1Low52.6Low63 Ų6396.5 Ų96.538%0.38253%0.533SS..Hα-helixtrans-69.9-44.1176.9172.70000110.8Y552 L553 R559 L560Y552-V556 HydrophobicContact CD1-CG2 3.88Å; Y552-V556 HydrophobicContact CE1-CG2 3.94Å; Y552-V556 WeakPolarHBondContact O-CG2 3.17Å; Y552-V556 PolarHBondContact O-N 2.96Å; L553-V556 PolarHBondContact O-N 2.89Å; V556-R559 PolarHBondContact O-N 3.25Å; V556-L560 HydrophobicContact CG1-CD1 4.28Å; V556-L560 PolarHBondContact O-N 2.72Å
557L53.9Low53.7Low44 Ų44100.2 Ų100.223%0.2354%0.539CS..Hα-helixtrans-63.5-40.5174.9-70.8167.8000111.7L553 R559 L560 V561 T593L553-L557 HydrophobicContact CD2-CD1 4.07Å; L553-L557 HydrophobicContact CG-CD1 3.9Å; L553-L557 HydrophobicContact CG-CG 4.39Å; L553-L557 VanDerWaalsContact O-CB 3.27Å; L553-L557 WeakPolarHBondContact O-CB 3.31Å; L553-L557 WeakPolarHBondContact O-CD1 3.34Å; L553-L557 WeakPolarHBondContact O-CG 3.2Å; L553-L557 PolarHBondContact O-N 3.03Å; L557-R559 VanDerWaalsContact C-N 3.3Å; L557-R559 PolarHBondContact O-N 3.37Å; L557-L560 HydrophobicContact CD2-CD1 4.34Å; L557-L560 WeakPolarHBondContact O-CB 3.33Å; L557-L560 PolarHBondContact O-N 2.77Å; L557-L560 VanDerWaalsContact O-N 3.15Å; L557-V561 WeakPolarHBondContact O-CG2 3.39Å; L557-V561 PolarHBondContact O-N 3.09Å; L557-T593 HydrophobicContact CD1-CG2 3.88Å
558A54.6Low54.3Low61 Ų6197.4 Ų97.450%0.50452%0.518SS..Hα-helixtrans-62.7-34.9173.700000112.6A554 V561A554-A558 VanDerWaalsContact O-CB 3.24Å; A554-A558 WeakPolarHBondContact O-CB 3.42Å; A554-A558 PolarHBondContact O-N 3.02Å; A558-V561 PolarHBondContact O-N 2.84Å
559R55.5Low54.6Low185 Ų185102 Ų10270%0.69853%0.528SS*.Hα-helixtrans-72.7-28.7173.8-74.8178.4180178.7-0.2113R555 V556 L557 V561 L562 P563R555-R559 WeakPolarHBondContact O-CG 3.04Å; R555-R559 PolarHBondContact O-N 3.37Å; R555-R559 VanDerWaalsContact O-N 3.1Å; V556-R559 PolarHBondContact O-N 3.25Å; L557-R559 VanDerWaalsContact C-N 3.3Å; L557-R559 PolarHBondContact O-N 3.37Å; R559-V561 VanDerWaalsContact C-N 3.29Å; R559-V561 PolarHBondContact O-N 3.22Å; R559-L562 PolarHBondContact O-N 3.01Å; R559-P563 WeakPolarHBondContact O-CD 3.44Å
560L57.4Low55.1Low100 Ų100100 Ų10052%0.52452%0.516SS..Hα-helixtrans-72.5-17.9172.9-76.8165000113.5V556 L557 P563 F564V556-L560 HydrophobicContact CG1-CD1 4.28Å; V556-L560 PolarHBondContact O-N 2.72Å; L557-L560 HydrophobicContact CD2-CD1 4.34Å; L557-L560 WeakPolarHBondContact O-CB 3.33Å; L557-L560 PolarHBondContact O-N 2.77Å; L557-L560 VanDerWaalsContact O-N 3.15Å; L560-P563 VanDerWaalsContact O-CD 3.28Å; L560-P563 WeakPolarHBondContact O-CD 3.22Å; L560-P563 VanDerWaalsContact O-CG 3.3Å; L560-P563 WeakPolarHBondContact O-CG 3.47Å; L560-F564 VanDerWaalsContact O-CD2 3.3Å; L560-F564 WeakPolarHBondContact O-CD2 3.37Å; L560-F564 WeakPolarHBondContact O-CE2 3.43Å
561V55.8Low55.6Low90 Ų9099 Ų9955%0.54550%0.498SS..Hα-helixtrans-78.7-25.4173.91770000112.1L557 A558 R559 F564L557-V561 WeakPolarHBondContact O-CG2 3.39Å; L557-V561 PolarHBondContact O-N 3.09Å; A558-V561 PolarHBondContact O-N 2.84Å; R559-V561 VanDerWaalsContact C-N 3.29Å; R559-V561 PolarHBondContact O-N 3.22Å; V561-F564 WeakPolarHBondContact O-CB 3.44Å; V561-F564 PolarHBondContact O-N 3.49Å
562L54.4Low55.9Low121 Ų12198.8 Ų98.863%0.63450%0.496SS*.G310 helixtrans-58.2-40.6179.5-72.6165.9000115R559 F564 K565R559-L562 PolarHBondContact O-N 3.01Å; L562-F564 PolarHBondContact O-N 3.02Å; L562-K565 PolarHBondContact O-N 3.17Å
563P57.1Low56.2Low88 Ų8899.2 Ų99.257%0.57151%0.506SS*.G310 helixtrans-70.1-6.1174.426.1-34.8000114.5R559 L560 K565 P566R559-P563 WeakPolarHBondContact O-CD 3.44Å; L560-P563 VanDerWaalsContact O-CD 3.28Å; L560-P563 WeakPolarHBondContact O-CD 3.22Å; L560-P563 VanDerWaalsContact O-CG 3.3Å; L560-P563 WeakPolarHBondContact O-CG 3.47Å; P563-K565 VanDerWaalsContact C-N 3.33Å; P563-P566 WeakPolarHBondContact O-CD 3.27Å
564F58.5Low56.6Low105 Ų105102.7 Ų102.746%0.46152%0.521SS..G310 helixtrans-81.1-5.4175-76.6-93.1000114L560 V561 L562 Y567 I568L560-F564 VanDerWaalsContact O-CD2 3.3Å; L560-F564 WeakPolarHBondContact O-CD2 3.37Å; L560-F564 WeakPolarHBondContact O-CE2 3.43Å; V561-F564 WeakPolarHBondContact O-CB 3.44Å; V561-F564 PolarHBondContact O-N 3.49Å; L562-F564 PolarHBondContact O-N 3.02Å; F564-Y567 AromaticContact CD1-CD1 3.81Å; F564-Y567 HydrophobicContact CD1-CD1 3.81Å; F564-Y567 HydrophobicContact CD1-CG 4.14Å; F564-Y567 HydrophobicContact CE1-CD1 4.25Å; F564-Y567 CarbonylContact O-C 3.21Å; F564-Y567 WeakPolarHBondContact O-CA 3.43Å; F564-Y567 WeakPolarHBondContact O-CB 3.37Å; F564-Y567 PolarHBondContact O-N 3.05Å; F564-I568 HydrophobicContact CB-CD1 4.47Å; F564-I568 WeakPolarHBondContact O-CG1 3.41Å; F564-I568 PolarHBondContact O-N 2.91Å
565K53.9Low56.8Low162 Ų162102.2 Ų102.270%0.70452%0.517SS*.Hα-helixtrans-50.7-47.7176.4-117.9-179.8179.3-179.30114.7L562 P563 Y567 R569L562-K565 PolarHBondContact O-N 3.17Å; P563-K565 VanDerWaalsContact C-N 3.33Å; K565-Y567 VanDerWaalsContact C-N 3.33Å; K565-R569 PolarHBondContact O-N 2.57Å
566P57.2Low56.9Low92 Ų9299 Ų9960%0.59752%0.517SS*.Hα-helixtrans-67.3-31.9173.924-33.5000113P563 R569 S570P563-P566 WeakPolarHBondContact O-CD 3.27Å; P566-R569 PolarHBondContact O-N 3Å; P566-S570 PolarHBondContact O-N 2.64Å
567Y62.1Low56.8Low138 Ų13899.6 Ų99.654%0.54152%0.521SS..Hα-helixtrans-68.8-40177.1-162.8-105.4000111.9F564 K565 R569 S570 I571F564-Y567 AromaticContact CD1-CD1 3.81Å; F564-Y567 HydrophobicContact CD1-CD1 3.81Å; F564-Y567 HydrophobicContact CD1-CG 4.14Å; F564-Y567 HydrophobicContact CE1-CD1 4.25Å; F564-Y567 CarbonylContact O-C 3.21Å; F564-Y567 WeakPolarHBondContact O-CA 3.43Å; F564-Y567 WeakPolarHBondContact O-CB 3.37Å; F564-Y567 PolarHBondContact O-N 3.05Å; K565-Y567 VanDerWaalsContact C-N 3.33Å; Y567-R569 VanDerWaalsContact C-N 3.27Å; Y567-R569 PolarHBondContact O-N 3.32Å; Y567-S570 WeakPolarHBondContact O-CB 3.31Å; Y567-S570 PolarHBondContact O-N 3.43Å; Y567-I571 HydrophobicContact CD1-CD1 3.49Å; Y567-I571 VanDerWaalsContact CD1-CD1 3.49Å; Y567-I571 HydrophobicContact CD1-CG1 4.25Å; Y567-I571 HydrophobicContact CE1-CD1 3.55Å; Y567-I571 HydrophobicContact CE1-CG1 4.23Å; Y567-I571 HydrophobicContact CG-CD1 4.46Å; Y567-I571 WeakPolarHBondContact O-CB 3.27Å; Y567-I571 VanDerWaalsContact O-CG1 3.29Å; Y567-I571 WeakPolarHBondContact O-CG1 3.49Å; Y567-I571 PolarHBondContact O-N 3.38Å
568I61.4Low57.3Low95 Ų95102 Ų10249%0.48753%0.531SS..Hα-helixtrans-61.5-36.3172.6-66165000110.8F564 I571 A572F564-I568 HydrophobicContact CB-CD1 4.47Å; F564-I568 WeakPolarHBondContact O-CG1 3.41Å; F564-I568 PolarHBondContact O-N 2.91Å; I568-I571 PolarHBondContact O-N 2.85Å; I568-A572 PolarHBondContact O-N 3.19Å
569R55.2Low57.9Low199 Ų199100.3 Ų100.375%0.75152%0.515SS*.Hα-helixtrans-70.3-36.3176.5-161.4176.8-176.7167.11.2112.7K565 P566 Y567 L573K565-R569 PolarHBondContact O-N 2.57Å; P566-R569 PolarHBondContact O-N 3Å; Y567-R569 VanDerWaalsContact C-N 3.27Å; Y567-R569 PolarHBondContact O-N 3.32Å; R569-L573 PolarHBondContact O-N 3.35Å
570S59Low58.3Low54 Ų5491.5 Ų91.538%0.37848%0.482SS..Hα-helixtrans-66-44.6171.6158.40000111.8P566 Y567 A572 L573 H574P566-S570 PolarHBondContact O-N 2.64Å; Y567-S570 WeakPolarHBondContact O-CB 3.31Å; Y567-S570 PolarHBondContact O-N 3.43Å; S570-A572 VanDerWaalsContact C-N 3.3Å; S570-A572 PolarHBondContact O-N 3.28Å; S570-L573 WeakPolarHBondContact O-CB 3.38Å; S570-L573 PolarHBondContact O-N 2.93Å; S570-L573 VanDerWaalsContact O-N 3.07Å; S570-H574 PolarHBondContact O-N 3.05Å; S570-H574 VanDerWaalsContact O-N 3.11Å
571I59.6Low58.9Low31 Ų3188.5 Ų88.516%0.15947%0.468CS..Hα-helixtrans-59.1-41175.2-72.6167.8000111.2Y567 I568 L573 H574 A575 V582 L586Y567-I571 HydrophobicContact CD1-CD1 3.49Å; Y567-I571 VanDerWaalsContact CD1-CD1 3.49Å; Y567-I571 HydrophobicContact CD1-CG1 4.25Å; Y567-I571 HydrophobicContact CE1-CD1 3.55Å; Y567-I571 HydrophobicContact CE1-CG1 4.23Å; Y567-I571 HydrophobicContact CG-CD1 4.46Å; Y567-I571 WeakPolarHBondContact O-CB 3.27Å; Y567-I571 VanDerWaalsContact O-CG1 3.29Å; Y567-I571 WeakPolarHBondContact O-CG1 3.49Å; Y567-I571 PolarHBondContact O-N 3.38Å; I568-I571 PolarHBondContact O-N 2.85Å; I571-L573 PolarHBondContact O-N 3.24Å; I571-H574 PolarHBondContact O-N 3.35Å; I571-A575 VanDerWaalsContact O-CB 3.27Å; I571-A575 WeakPolarHBondContact O-CB 3.4Å; I571-A575 PolarHBondContact O-N 3.39Å; I571-V582 HydrophobicContact CG2-CB 4.36Å; I571-V582 HydrophobicContact CG2-CG1 3.28Å; I571-V582 HydrophobicContact CG2-CG2 4.21Å; I571-L586 HydrophobicContact CD1-CD2 4.37Å; I571-L586 HydrophobicContact CG2-CD1 4.46Å
572A57.6Low59.5Low63 Ų6385.2 Ų85.252%0.52145%0.448SS..Hα-helixtrans-62.7-30.217700000113I568 S570I568-A572 PolarHBondContact O-N 3.19Å; S570-A572 VanDerWaalsContact C-N 3.3Å; S570-A572 PolarHBondContact O-N 3.28Å
573L57Low60.1Low136 Ų13680.4 Ų80.471%0.71243%0.428SS*.Hα-helixtrans-75-40.3174.7-112.2110.3000112.1R569 S570 I571R569-L573 PolarHBondContact O-N 3.35Å; S570-L573 WeakPolarHBondContact O-CB 3.38Å; S570-L573 PolarHBondContact O-N 2.93Å; S570-L573 VanDerWaalsContact O-N 3.07Å; I571-L573 PolarHBondContact O-N 3.24Å
574H57.2Low60.7Low108 Ų10877.2 Ų77.250%0.541%0.406SS..Hα-helixtrans-76.6-22.8177.1-78.4-56.2000113.9S570 I571 V576 T577 E578 V582S570-H574 PolarHBondContact O-N 3.05Å; S570-H574 VanDerWaalsContact O-N 3.11Å; I571-H574 PolarHBondContact O-N 3.35Å; H574-V576 PolarHBondContact O-N 3.44Å; H574-V576 VanDerWaalsContact O-N 3.11Å; H574-T577 PolarHBondContact O-N 3.1Å; H574-T577 PolarHBondContact O-OG1 3.32Å; H574-E578 PolarHBondContact O-N 2.86Å; H574-V582 HydrophobicContact CB-CG2 4.43Å
575A55.7Low61.2Low37 Ų3775.8 Ų75.831%0.30641%0.409SS..THydrogen-bonded Turntrans-61-19.7175.900000113.1I571 T577 S579 V582I571-A575 VanDerWaalsContact O-CB 3.27Å; I571-A575 WeakPolarHBondContact O-CB 3.4Å; I571-A575 PolarHBondContact O-N 3.39Å; A575-T577 VanDerWaalsContact C-N 3.32Å; A575-S579 WeakPolarHBondContact O-CB 3.26Å; A575-V582 HydrophobicContact CB-CG1 4.28Å
576V54.4Low61.9Low106 Ų10672.2 Ų72.264%0.64240%0.397SS*.THydrogen-bonded Turntrans-70.1-29.4176.5-1770000111.7H574H574-V576 PolarHBondContact O-N 3.44Å; H574-V576 VanDerWaalsContact O-N 3.11Å
577T56Low62.5Low77 Ų7770 Ų7047%0.47238%0.378SS..THydrogen-bonded Turntrans-112.2-27.8-175.652.10000114.5H574 A575H574-T577 PolarHBondContact O-N 3.1Å; H574-T577 PolarHBondContact O-OG1 3.32Å; A575-T577 VanDerWaalsContact C-N 3.32Å
578E63.5Low63Low93 Ų9365.9 Ų65.944%0.43536%0.362SS..  trans-138.357.7-174.1-57.7-174.8179.300110.8H574 G580 T581 V582H574-E578 PolarHBondContact O-N 2.86Å; E578-G580 PolarHBondContact O-N 2.97Å; E578-T581 WeakPolarHBondContact CB-OG1 3.4Å; E578-T581 PolarHBondContact O-OG1 2.9Å; E578-T581 VanDerWaalsContact O-OG1 3.11Å; E578-V582 WeakPolarHBondContact O-CB 3.3Å; E578-V582 WeakPolarHBondContact O-CG2 3.4Å; E578-V582 PolarHBondContact O-N 2.9Å
579S66.8Low63.3Low26 Ų2664.2 Ų64.218%0.18236%0.362CS..Hα-helixtrans-62.4-30-176.454.70000114D418 K421 A575 G583D418-S579 PolarHBondContact OD1-N 3.3Å; K421-S579 WeakPolarHBondContact CD-OG 3.42Å; K421-S579 WeakPolarHBondContact CE-OG 3.43Å; K421-S579 PolarHBondContact NZ-OG 3.24Å; A575-S579 WeakPolarHBondContact O-CB 3.26Å; S579-G583 PolarHBondContact O-N 3.21Å
580G65.7Low64Low0 Ų058.4 Ų58.40%035%0.352CS..Hα-helixtrans-67-53.9179.300000111.4S414 D418 E578 V582 G583 L584S414-G580 WeakPolarHBondContact OG-CA 3.42Å; S414-G580 PolarHBondContact OG-O 2.92Å; S414-G580 VanDerWaalsContact OG-O 3.12Å; D418-G580 WeakPolarHBondContact OD1-CA 3.47Å; D418-G580 PolarHBondContact OD1-N 2.99Å; E578-G580 PolarHBondContact O-N 2.97Å; G580-V582 VanDerWaalsContact C-N 3.32Å; G580-V582 PolarHBondContact O-N 3.2Å; G580-G583 PolarHBondContact O-N 3.12Å; G580-G583 VanDerWaalsContact O-N 3.17Å; G580-L584 PolarHBondContact O-N 2.91Å
581T68.3Low64.4Low37 Ų3756.8 Ų56.823%0.22734%0.34CS..Hα-helixtrans-64.1-36.4179.953.60000112.2S414 D418 E578 L584 S585S414-T581 PolarHBondContact OG-N 3.4Å; S414-T581 VanDerWaalsContact OG-N 3.08Å; D418-T581 PolarHBondContact OD2-N 3.07Å; E578-T581 WeakPolarHBondContact CB-OG1 3.4Å; E578-T581 PolarHBondContact O-OG1 2.9Å; E578-T581 VanDerWaalsContact O-OG1 3.11Å; T581-L584 PolarHBondContact O-N 3.37Å; T581-S585 WeakPolarHBondContact O-CB 3.45Å; T581-S585 PolarHBondContact O-N 3.1Å; T581-S585 PolarHBondContact O-OG 3.05Å
582V69Low64.8Low21 Ų2157.8 Ų57.813%0.12735%0.346CS..Hα-helixtrans-61.4-47.8172.1163.50000111.3I571 H574 A575 E578 G580 L584 S585 L586I571-V582 HydrophobicContact CG2-CB 4.36Å; I571-V582 HydrophobicContact CG2-CG1 3.28Å; I571-V582 HydrophobicContact CG2-CG2 4.21Å; H574-V582 HydrophobicContact CB-CG2 4.43Å; A575-V582 HydrophobicContact CB-CG1 4.28Å; E578-V582 WeakPolarHBondContact O-CB 3.3Å; E578-V582 WeakPolarHBondContact O-CG2 3.4Å; E578-V582 PolarHBondContact O-N 2.9Å; G580-V582 VanDerWaalsContact C-N 3.32Å; G580-V582 PolarHBondContact O-N 3.2Å; V582-L584 PolarHBondContact O-N 3.41Å; V582-S585 PolarHBondContact O-N 3.08Å; V582-L586 HydrophobicContact CG1-CD1 4.12Å; V582-L586 PolarHBondContact O-N 3.47Å
583G67.8Low65.4Low20 Ų2057.7 Ų57.721%0.20634%0.339CS..Hα-helixtrans-59.8-45.8177.700000112.1S579 G580 S585 L586 F587S579-G583 PolarHBondContact O-N 3.21Å; G580-G583 PolarHBondContact O-N 3.12Å; G580-G583 VanDerWaalsContact O-N 3.17Å; G583-S585 VanDerWaalsContact C-N 3.34Å; G583-S585 PolarHBondContact O-N 3.03Å; G583-L586 PolarHBondContact O-N 3.38Å; G583-F587 WeakPolarHBondContact O-CB 3.29Å; G583-F587 PolarHBondContact O-N 3.35Å
584L69.1Low65.9Low21 Ų2153.2 Ų53.211%0.1133%0.326CS..Hα-helixtrans-61.5-40.4176.1-175.762.1000112.3D410 G580 T581 V582 F587 Y588D410-L584 HydrophobicContact CB-CD1 3.77Å; G580-L584 PolarHBondContact O-N 2.91Å; T581-L584 PolarHBondContact O-N 3.37Å; V582-L584 PolarHBondContact O-N 3.41Å; L584-F587 PolarHBondContact O-N 3.39Å; L584-Y588 HydrophobicContact CD1-CD2 4.01Å; L584-Y588 HydrophobicContact CD1-CE2 3.46Å; L584-Y588 VanDerWaalsContact CD1-CE2 3.46Å; L584-Y588 HydrophobicContact CD2-CE2 4.11Å; L584-Y588 HydrophobicContact CG-CD2 3.94Å; L584-Y588 HydrophobicContact CG-CE2 3.62Å; L584-Y588 WeakPolarHBondContact O-CD2 3.47Å; L584-Y588 PolarHBondContact O-N 3.1Å
585S69.7Low66.3Low75 Ų7550.8 Ų50.852%0.52431%0.314SS..Hα-helixtrans-66.1-45178.9-60.50000112.2T581 V582 G583 F587 Y588 A589T581-S585 WeakPolarHBondContact O-CB 3.45Å; T581-S585 PolarHBondContact O-N 3.1Å; T581-S585 PolarHBondContact O-OG 3.05Å; V582-S585 PolarHBondContact O-N 3.08Å; G583-S585 VanDerWaalsContact C-N 3.34Å; G583-S585 PolarHBondContact O-N 3.03Å; S585-F587 VanDerWaalsContact C-N 3.34Å; S585-F587 PolarHBondContact O-N 3.23Å; S585-Y588 PolarHBondContact O-N 3.41Å; S585-A589 WeakPolarHBondContact O-CB 3.43Å; S585-A589 PolarHBondContact O-N 3.22Å
586L68.7Low66.8Low87 Ų8750.9 Ų50.946%0.45531%0.309SS..Hα-helixtrans-64.1-38.6175.1-73.1171000112I571 V582 G583 A589 S590I571-L586 HydrophobicContact CD1-CD2 4.37Å; I571-L586 HydrophobicContact CG2-CD1 4.46Å; V582-L586 HydrophobicContact CG1-CD1 4.12Å; V582-L586 PolarHBondContact O-N 3.47Å; G583-L586 PolarHBondContact O-N 3.38Å; L586-A589 PolarHBondContact O-N 3.35Å; L586-S590 WeakPolarHBondContact O-CB 3.22Å; L586-S590 PolarHBondContact O-N 2.88Å; L586-S590 PolarHBondContact O-OG 3.5Å
587F69.6Low67.5Low45 Ų4550 Ų5020%0.19730%0.298CS..Hα-helixtrans-61.5-44.8174.8173.9-99.5000112.1N99 G583 L584 S585 S590 S591N99-F587 HydrophobicContact CB-CE2 3.96Å; N99-F587 HydrophobicContact CB-CZ 4.04Å; N99-F587 VanDerWaalsContact ND2-CE2 3.33Å; N99-F587 WeakPolarHBondContact ND2-CE2 3.32Å; N99-F587 WeakPolarHBondContact ND2-CZ 3.49Å; G583-F587 WeakPolarHBondContact O-CB 3.29Å; G583-F587 PolarHBondContact O-N 3.35Å; L584-F587 PolarHBondContact O-N 3.39Å; S585-F587 VanDerWaalsContact C-N 3.34Å; S585-F587 PolarHBondContact O-N 3.23Å; F587-S590 PolarHBondContact O-OG 3.23Å; F587-S591 VanDerWaalsContact O-CB 3.29Å; F587-S591 WeakPolarHBondContact O-CB 3.47Å; F587-S591 PolarHBondContact O-N 2.88Å; F587-S591 VanDerWaalsContact O-N 3.08Å; F587-S591 PolarHBondContact O-OG 3.31Å
588Y71Confident68.1Low53 Ų5348.4 Ų48.421%0.20829%0.285CS..Hα-helixtrans-69.7-38.4176.3-74.9-46.9000112.8D410 L584 S585 S591 L592D410-Y588 VanDerWaalsContact CB-OH 3.27Å; D410-Y588 WeakPolarHBondContact CB-OH 3.12Å; D410-Y588 PolarHBondContact OD2-OH 2.74Å; L584-Y588 HydrophobicContact CD1-CD2 4.01Å; L584-Y588 HydrophobicContact CD1-CE2 3.46Å; L584-Y588 VanDerWaalsContact CD1-CE2 3.46Å; L584-Y588 HydrophobicContact CD2-CE2 4.11Å; L584-Y588 HydrophobicContact CG-CD2 3.94Å; L584-Y588 HydrophobicContact CG-CE2 3.62Å; L584-Y588 WeakPolarHBondContact O-CD2 3.47Å; L584-Y588 PolarHBondContact O-N 3.1Å; S585-Y588 PolarHBondContact O-N 3.41Å; Y588-S591 PolarHBondContact O-N 3.17Å; Y588-L592 WeakPolarHBondContact O-CB 3.39Å; Y588-L592 PolarHBondContact O-N 2.92Å
589A69.3Low68.1Low59 Ų5944.7 Ų44.749%0.48827%0.268SS..Hα-helixtrans-62.7-46.1177.100000112.3S585 L586 L592S585-A589 WeakPolarHBondContact O-CB 3.43Å; S585-A589 PolarHBondContact O-N 3.22Å; L586-A589 PolarHBondContact O-N 3.35Å; A589-L592 WeakPolarHBondContact O-CB 3.44Å; A589-L592 PolarHBondContact O-N 3.28Å
590S68.6Low68.2Low78 Ų7847 Ų4755%0.54528%0.278SS..Hα-helixtrans-66.7-39.7177.155.20000112.6L586 F587 L592L586-S590 WeakPolarHBondContact O-CB 3.22Å; L586-S590 PolarHBondContact O-N 2.88Å; L586-S590 PolarHBondContact O-OG 3.5Å; F587-S590 PolarHBondContact O-OG 3.23Å; S590-L592 VanDerWaalsContact C-N 3.3Å; S590-L592 PolarHBondContact O-N 2.98Å
591S68.9Low68.3Low19 Ų1955.5 Ų55.513%0.13331%0.31CS..Hα-helixtrans-66.4-32.6177.1-63.70000112.5F587 Y588 T593 G594 F595F587-S591 VanDerWaalsContact O-CB 3.29Å; F587-S591 WeakPolarHBondContact O-CB 3.47Å; F587-S591 PolarHBondContact O-N 2.88Å; F587-S591 VanDerWaalsContact O-N 3.08Å; F587-S591 PolarHBondContact O-OG 3.31Å; Y588-S591 PolarHBondContact O-N 3.17Å; S591-T593 VanDerWaalsContact C-N 3.33Å; S591-T593 PolarHBondContact O-N 3.32Å; S591-G594 PolarHBondContact O-N 3.33Å; S591-F595 WeakPolarHBondContact O-CD2 3.13Å; S591-F595 PolarHBondContact O-N 2.76Å
592L67.5Low68.4Low53 Ų5354.4 Ų54.428%0.27730%0.302SS..Hα-helixtrans-57.5-42.8-176.7-179.565.2000112.4L535 Y588 A589 S590 G594 F595 L596L535-L592 HydrophobicContact CD1-CD1 3.91Å; L535-L592 HydrophobicContact CD1-CD2 3.7Å; L535-L592 HydrophobicContact CD1-CG 4.45Å; Y588-L592 WeakPolarHBondContact O-CB 3.39Å; Y588-L592 PolarHBondContact O-N 2.92Å; A589-L592 WeakPolarHBondContact O-CB 3.44Å; A589-L592 PolarHBondContact O-N 3.28Å; S590-L592 VanDerWaalsContact C-N 3.3Å; S590-L592 PolarHBondContact O-N 2.98Å; L592-G594 PolarHBondContact O-N 3.13Å; L592-F595 PolarHBondContact O-N 3.44Å; L592-L596 HydrophobicContact CD1-CD1 4.16Å; L592-L596 HydrophobicContact CD1-CG 4.09Å; L592-L596 HydrophobicContact CD2-CD1 4.5Å; L592-L596 HydrophobicContact CG-CD1 3.93Å; L592-L596 HydrophobicContact CG-CG 4.29Å; L592-L596 WeakPolarHBondContact O-CB 3.24Å; L592-L596 WeakPolarHBondContact O-CG 3.28Å; L592-L596 PolarHBondContact O-N 3.05Å
593T69.6Low68.5Low60 Ų6054.9 Ų54.937%0.36831%0.306SS..Hα-helixtrans-61.5-44.3-177.8-39.20000111.7L557 S591 Q597L557-T593 HydrophobicContact CD1-CG2 3.88Å; S591-T593 VanDerWaalsContact C-N 3.33Å; S591-T593 PolarHBondContact O-N 3.32Å; T593-Q597 PolarHBondContact O-N 3.15Å
594G67.2Low68.7Low43 Ų4357.4 Ų57.444%0.44332%0.318SS..Hα-helixtrans-67.9-39176.200000112.8S591 L592 F598S591-G594 PolarHBondContact O-N 3.33Å; L592-G594 PolarHBondContact O-N 3.13Å; G594-F598 PolarHBondContact O-N 3.14Å; G594-F598 VanDerWaalsContact O-N 3.14Å
595F66.8Low68.8Low57 Ų5759.9 Ų59.925%0.2533%0.329CS..Hα-helixtrans-65.4-40.1176.3-79.4-60.8000112.9S591 L592 F598 M599S591-F595 WeakPolarHBondContact O-CD2 3.13Å; S591-F595 PolarHBondContact O-N 2.76Å; L592-F595 PolarHBondContact O-N 3.44Å; F595-F598 PolarHBondContact O-N 3.28Å; F595-M599 VanDerWaalsContact O-CB 3.32Å; F595-M599 WeakPolarHBondContact O-CB 2.66Å; F595-M599 VanDerWaalsContact O-CG 3.28Å; F595-M599 WeakPolarHBondContact O-CG 3.47Å; F595-M599 PolarHBondContact O-N 2.89Å
596L65.4Low69Low39 Ų3956.4 Ų56.420%0.20430%0.304CS..Hα-helixtrans-64.9-41.7178-76.9172.7000112.1L592 M599 L600L592-L596 HydrophobicContact CD1-CD1 4.16Å; L592-L596 HydrophobicContact CD1-CG 4.09Å; L592-L596 HydrophobicContact CD2-CD1 4.5Å; L592-L596 HydrophobicContact CG-CD1 3.93Å; L592-L596 HydrophobicContact CG-CG 4.29Å; L592-L596 WeakPolarHBondContact O-CB 3.24Å; L592-L596 WeakPolarHBondContact O-CG 3.28Å; L592-L596 PolarHBondContact O-N 3.05Å; L596-M599 WeakPolarHBondContact O-CB 2.84Å; L596-M599 PolarHBondContact O-N 3.29Å; L596-L600 WeakPolarHBondContact O-CG 3.25Å; L596-L600 PolarHBondContact O-N 2.93Å
597Q69.5Low69.4Low87 Ų8756 Ų5641%0.40730%0.3SS..Hα-helixtrans-62.2-46.2175.1-72.8-179.8-17.200111.8L553 T593 M599 L600 R601L553-Q597 HydrophobicContact CD2-CG 4.3Å; T593-Q597 PolarHBondContact O-N 3.15Å; Q597-M599 VanDerWaalsContact C-N 3.32Å; Q597-M599 PolarHBondContact O-N 3.37Å; Q597-L600 PolarHBondContact O-N 3.18Å; Q597-R601 PolarHBondContact O-N 3.47Å
598F67.3Low69.7Low44 Ų4458.9 Ų58.919%0.19332%0.318CS..Hα-helixtrans-60.9-42176.4-176-100.7000111.7Y524 S528 G594 F595 R601 Q602Y524-F598 HydrophobicContact CD1-CZ 4.06Å; S528-F598 VanDerWaalsContact OG-CD1 3.24Å; S528-F598 WeakPolarHBondContact OG-CD1 3.29Å; S528-F598 WeakPolarHBondContact OG-CE1 3.32Å; G594-F598 PolarHBondContact O-N 3.14Å; G594-F598 VanDerWaalsContact O-N 3.14Å; F595-F598 PolarHBondContact O-N 3.28Å; F598-R601 PolarHBondContact O-N 2.93Å; F598-Q602 HydrophobicContact CD1-CG 4.1Å; F598-Q602 HydrophobicContact CE1-CG 3.66Å; F598-Q602 HydrophobicContact CE2-CG 4.2Å; F598-Q602 HydrophobicContact CZ-CG 3.71Å; F598-Q602 WeakPolarHBondContact O-CG 3.43Å; F598-Q602 PolarHBondContact O-N 3.33Å
599M64.9Low70.1Confident15 Ų1558.9 Ų58.97%0.07432%0.32CS..Hα-helixtrans-56.3-50.4175.8-89.3-102.137.100113.7Y525 S528 A529 L532 F595 L596 Q597 Q602 S603Y525-M599 HydrophobicContact CE2-CE 4.39Å; S528-M599 VanDerWaalsContact CB-CE 3.41Å; S528-M599 WeakPolarHBondContact CB-SD 3.35Å; A529-M599 HydrophobicContact CB-CE 4.47Å; A529-M599 PolarHBondContact N-SD 3.15Å; A529-M599 VanDerWaalsContact N-SD 3.4Å; L532-M599 HydrophobicContact CB-SD 4.1Å; L532-M599 HydrophobicContact CD1-SD 4.26Å; F595-M599 VanDerWaalsContact O-CB 3.32Å; F595-M599 WeakPolarHBondContact O-CB 2.66Å; F595-M599 VanDerWaalsContact O-CG 3.28Å; F595-M599 WeakPolarHBondContact O-CG 3.47Å; F595-M599 PolarHBondContact O-N 2.89Å; L596-M599 WeakPolarHBondContact O-CB 2.84Å; L596-M599 PolarHBondContact O-N 3.29Å; Q597-M599 VanDerWaalsContact C-N 3.32Å; Q597-M599 PolarHBondContact O-N 3.37Å; M599-Q602 PolarHBondContact O-N 3.28Å; M599-S603 WeakPolarHBondContact O-CB 3.39Å; M599-S603 PolarHBondContact O-N 3.21Å
600L67.5Low70.7Confident75 Ų7556 Ų5639%0.39330%0.297SS..Hα-helixtrans-61.2-46.9-178.3-73.6169.2000110.8L553 L596 Q597 Q602 S603 T604L553-L600 HydrophobicContact CD2-CD1 4.29Å; L596-L600 WeakPolarHBondContact O-CG 3.25Å; L596-L600 PolarHBondContact O-N 2.93Å; Q597-L600 PolarHBondContact O-N 3.18Å; L600-Q602 PolarHBondContact O-N 2.78Å; L600-S603 WeakPolarHBondContact O-CB 3.18Å; L600-S603 PolarHBondContact O-N 2.95Å; L600-S603 VanDerWaalsContact O-N 3.14Å; L600-T604 PolarHBondContact O-N 2.8Å; L600-T604 PolarHBondContact O-OG1 2.94Å
601R69.4Low71.3Confident178 Ų17855.2 Ų55.267%0.67229%0.288SS*.Hα-helixtrans-58.2-48.2176.2-178.1179.7-78.1-172.7-5.6111.7Q597 F598 S603 T604 E605Q597-R601 PolarHBondContact O-N 3.47Å; F598-R601 PolarHBondContact O-N 2.93Å; R601-S603 VanDerWaalsContact C-N 3.27Å; R601-S603 PolarHBondContact O-N 3.28Å; R601-T604 PolarHBondContact O-N 3.14Å; R601-E605 WeakPolarHBondContact O-CG 3.48Å; R601-E605 PolarHBondContact O-N 2.77Å
602Q70Confident71.9Confident14 Ų1454.6 Ų54.67%0.06528%0.284CS..Hα-helixtrans-66.4-28.6178.7-65.8-42.1126.800113.2F598 M599 L600 E605 V606F598-Q602 HydrophobicContact CD1-CG 4.1Å; F598-Q602 HydrophobicContact CE1-CG 3.66Å; F598-Q602 HydrophobicContact CE2-CG 4.2Å; F598-Q602 HydrophobicContact CZ-CG 3.71Å; F598-Q602 WeakPolarHBondContact O-CG 3.43Å; F598-Q602 PolarHBondContact O-N 3.33Å; M599-Q602 PolarHBondContact O-N 3.28Å; L600-Q602 PolarHBondContact O-N 2.78Å; Q602-E605 PolarHBondContact NE2-OE2 2.75Å; Q602-V606 PolarHBondContact O-N 2.8Å; Q602-V606 VanDerWaalsContact O-N 3.1Å
603S70.5Confident72.8Confident30 Ų3052.1 Ų52.121%0.2127%0.271CS..Hα-helixtrans-67.2-48.5175.1-165.60000111.1M599 L600 R601 E605 V606 E607M599-S603 WeakPolarHBondContact O-CB 3.39Å; M599-S603 PolarHBondContact O-N 3.21Å; L600-S603 WeakPolarHBondContact O-CB 3.18Å; L600-S603 PolarHBondContact O-N 2.95Å; L600-S603 VanDerWaalsContact O-N 3.14Å; R601-S603 VanDerWaalsContact C-N 3.27Å; R601-S603 PolarHBondContact O-N 3.28Å; S603-E605 VanDerWaalsContact C-N 3.32Å; S603-E605 PolarHBondContact O-N 3.42Å; S603-V606 PolarHBondContact O-N 2.74Å; S603-E607 WeakPolarHBondContact O-CB 3.49Å; S603-E607 PolarHBondContact O-N 3.5Å
604T71.9Confident73.6Confident74 Ų7450.5 Ų50.545%0.45426%0.259SS..Hα-helixtrans-61.5-41176.9-500000111.4L600 R601 V606 E607 N608L600-T604 PolarHBondContact O-N 2.8Å; L600-T604 PolarHBondContact O-OG1 2.94Å; R601-T604 PolarHBondContact O-N 3.14Å; T604-V606 PolarHBondContact O-N 2.63Å; T604-E607 PolarHBondContact O-N 3.23Å; T604-N608 WeakPolarHBondContact O-CB 3.46Å; T604-N608 PolarHBondContact O-N 3.26Å; T604-N608 PolarHBondContact O-ND2 3.3Å
605E71.2Confident74.4Confident73 Ų7349.9 Ų49.934%0.34124%0.243SC..Hα-helixtrans-62.2-42.7176.1-75.8179.1-17600112.6R601 Q602 S603 M609R601-E605 WeakPolarHBondContact O-CG 3.48Å; R601-E605 PolarHBondContact O-N 2.77Å; Q602-E605 PolarHBondContact NE2-OE2 2.75Å; S603-E605 VanDerWaalsContact C-N 3.32Å; S603-E605 PolarHBondContact O-N 3.42Å; E605-M609 WeakPolarHBondContact O-CG 3.31Å; E605-M609 PolarHBondContact O-N 3.42Å; E605-M609 VanDerWaalsContact O-N 3.11Å
606V75.4Confident75.4Confident1 Ų147.3 Ų47.31%0.00623%0.232CC..Hα-helixtrans-68.8-40.4177.2159.50000111.9Y379 W522 Y525 Q602 S603 T604 M609 M610Y379-V606 HydrophobicContact CE1-CG1 4.22Å; W522-V606 HydrophobicContact CE3-CG1 3.55Å; W522-V606 HydrophobicContact CE3-CG2 4.22Å; W522-V606 HydrophobicContact CH2-CG1 4.42Å; W522-V606 HydrophobicContact CZ3-CG1 3.32Å; Y525-V606 HydrophobicContact CD1-CG1 4.46Å; Y525-V606 HydrophobicContact CD2-CB 4.16Å; Y525-V606 HydrophobicContact CD2-CG1 4.47Å; Y525-V606 HydrophobicContact CD2-CG2 4.25Å; Y525-V606 HydrophobicContact CG-CB 4.15Å; Y525-V606 HydrophobicContact CG-CG1 4.26Å; Y525-V606 HydrophobicContact CG-CG2 3.87Å; Q602-V606 PolarHBondContact O-N 2.8Å; Q602-V606 VanDerWaalsContact O-N 3.1Å; S603-V606 PolarHBondContact O-N 2.74Å; T604-V606 PolarHBondContact O-N 2.63Å; V606-M609 PolarHBondContact O-N 2.93Å; V606-M610 HydrophobicContact CG1-CG 4.08Å; V606-M610 WeakPolarHBondContact O-CB 3.49Å; V606-M610 WeakPolarHBondContact O-CG 3.18Å; V606-M610 PolarHBondContact O-N 2.82Å
607E77.1Confident76.5Confident78 Ų7846.2 Ų46.236%0.36423%0.226SC..Hα-helixtrans-59.7-46.7175.7-174.3173.5-170.600111.2S603 T604 M609 M610 V611S603-E607 WeakPolarHBondContact O-CB 3.49Å; S603-E607 PolarHBondContact O-N 3.5Å; T604-E607 PolarHBondContact O-N 3.23Å; E607-M609 VanDerWaalsContact C-N 3.31Å; E607-M609 PolarHBondContact O-N 3.43Å; E607-M610 WeakPolarHBondContact O-CB 3.16Å; E607-M610 PolarHBondContact O-N 3.16Å; E607-M610 VanDerWaalsContact O-N 3.12Å; E607-V611 PolarHBondContact O-N 3.37Å
608N75.7Confident77.4Confident107 Ų10745.3 Ų45.357%0.57222%0.222SC*.Hα-helixtrans-58.8-41175.8-71.5-15.5000112.4T604T604-N608 WeakPolarHBondContact O-CB 3.46Å; T604-N608 PolarHBondContact O-N 3.26Å; T604-N608 PolarHBondContact O-ND2 3.3Å
609M77.7Confident78.4Confident52 Ų5244.1 Ų44.126%0.25622%0.217SC..Hα-helixtrans-74.3-27.7177.7-68.5-177.5-178.100113.1L518 S521 E605 V606 E607 V611 S612L518-M609 HydrophobicContact CB-CB 4.41Å; L518-M609 HydrophobicContact CD1-CB 3.69Å; L518-M609 HydrophobicContact CD1-SD 4.48Å; S521-M609 WeakPolarHBondContact CB-SD 3.17Å; S521-M609 WeakPolarHBondContact OG-CE 3.3Å; S521-M609 PolarHBondContact OG-SD 2.95Å; E605-M609 WeakPolarHBondContact O-CG 3.31Å; E605-M609 PolarHBondContact O-N 3.42Å; E605-M609 VanDerWaalsContact O-N 3.11Å; V606-M609 PolarHBondContact O-N 2.93Å; E607-M609 VanDerWaalsContact C-N 3.31Å; E607-M609 PolarHBondContact O-N 3.43Å; M609-V611 VanDerWaalsContact C-N 3.28Å; M609-V611 PolarHBondContact O-N 3.5Å; M609-S612 PolarHBondContact O-N 2.77Å
610M82.2Confident79.5Confident0 Ų043.6 Ų43.60%022%0.215CC..Hα-helixtrans-68.5-25.7178.7-81.5-77.8123.100113V374 Y379 Y382 L518 W522 V606 E607 S612 V613 E614V374-M610 HydrophobicContact CB-CB 4.38Å; V374-M610 HydrophobicContact CG1-CB 4.07Å; V374-M610 HydrophobicContact CG2-CB 3.9Å; Y379-M610 HydrophobicContact CD1-CG 4.09Å; Y379-M610 HydrophobicContact CD1-SD 3.85Å; Y379-M610 HydrophobicContact CE1-CB 4.35Å; Y379-M610 HydrophobicContact CE1-CG 3.49Å; Y379-M610 VanDerWaalsContact CE1-CG 3.49Å; Y379-M610 HydrophobicContact CE1-SD 3.91Å; Y379-M610 HydrophobicContact CG-SD 4.39Å; Y382-M610 HydrophobicContact CD1-CE 4.2Å; Y382-M610 HydrophobicContact CD2-CE 4.49Å; Y382-M610 HydrophobicContact CE1-CE 4.44Å; Y382-M610 HydrophobicContact CG-CE 4.24Å; L518-M610 HydrophobicContact CD1-CE 3.45Å; L518-M610 VanDerWaalsContact CD1-CE 3.45Å; L518-M610 HydrophobicContact CD2-CE 3.19Å; L518-M610 HydrophobicContact CG-CE 3.86Å; W522-M610 HydrophobicContact CE3-CE 4.08Å; W522-M610 HydrophobicContact CZ3-CE 3.99Å; W522-M610 HydrophobicContact CZ3-SD 4.43Å; V606-M610 HydrophobicContact CG1-CG 4.08Å; V606-M610 WeakPolarHBondContact O-CB 3.49Å; V606-M610 WeakPolarHBondContact O-CG 3.18Å; V606-M610 PolarHBondContact O-N 2.82Å; E607-M610 WeakPolarHBondContact O-CB 3.16Å; E607-M610 PolarHBondContact O-N 3.16Å; E607-M610 VanDerWaalsContact O-N 3.12Å; M610-S612 PolarHBondContact O-N 3.45Å; M610-V613 HydrophobicContact CE-CB 4.35Å; M610-V613 HydrophobicContact CE-CG2 3.79Å; M610-V613 WeakPolarHBondContact O-CA 3.4Å; M610-V613 WeakPolarHBondContact O-CB 3.46Å; M610-V613 PolarHBondContact O-N 2.83Å; M610-V613 HydrophobicContact SD-CB 4.31Å; M610-V613 HydrophobicContact SD-CG2 4.36Å; M610-E614 PolarHBondContact O-N 3.32Å
611V80.9Confident80.4Confident60 Ų6047.1 Ų47.136%0.36423%0.227SC..Hα-helixtrans-54.3-40.8171.9178.70000110.8V374 E607 M609 V613 E614 R615V374-V611 HydrophobicContact CG2-CB 4.4Å; V374-V611 HydrophobicContact CG2-CG2 3.66Å; E607-V611 PolarHBondContact O-N 3.37Å; M609-V611 VanDerWaalsContact C-N 3.28Å; M609-V611 PolarHBondContact O-N 3.5Å; V611-V613 VanDerWaalsContact C-N 3.34Å; V611-V613 PolarHBondContact O-N 3.02Å; V611-E614 WeakPolarHBondContact O-CB 3.48Å; V611-E614 PolarHBondContact O-N 3.2Å; V611-R615 WeakPolarHBondContact O-CG 3.48Å; V611-R615 PolarHBondContact O-N 3.31Å; V611-R615 VanDerWaalsContact O-N 3.17Å
612S83Confident81.3Confident7 Ų740.1 Ų40.15%0.04920%0.203CC..Hα-helixtrans-70.7-29.4177-57.60000113.2H514 M609 M610 I616H514-S612 PolarHBondContact ND1-OG 3.03Å; M609-S612 PolarHBondContact O-N 2.77Å; M610-S612 PolarHBondContact O-N 3.45Å; S612-I616 VanDerWaalsContact O-CG1 3.26Å; S612-I616 WeakPolarHBondContact O-CG1 3.45Å; S612-I616 PolarHBondContact O-N 2.85Å; S612-I616 VanDerWaalsContact O-N 3.08Å
613V86.4Confident82.1Confident0 Ų044.5 Ų44.50%023%0.232CC..Hα-helixtrans-70.5-39.2173.9178.50000110.9T378 Y382 L484 L515 L518 M610 V611 R615 I616 I617T378-V613 HydrophobicContact CG2-CB 4.46Å; T378-V613 HydrophobicContact CG2-CG1 4.25Å; Y382-V613 HydrophobicContact CD2-CG1 3.92Å; Y382-V613 HydrophobicContact CD2-CG2 4.41Å; Y382-V613 HydrophobicContact CG-CG1 4.45Å; L484-V613 HydrophobicContact CD1-CG1 4.38Å; L515-V613 HydrophobicContact CD1-CG2 4.08Å; L518-V613 HydrophobicContact CD2-CG2 3.33Å; M610-V613 HydrophobicContact CE-CB 4.35Å; M610-V613 HydrophobicContact CE-CG2 3.79Å; M610-V613 WeakPolarHBondContact O-CA 3.4Å; M610-V613 WeakPolarHBondContact O-CB 3.46Å; M610-V613 PolarHBondContact O-N 2.83Å; M610-V613 HydrophobicContact SD-CB 4.31Å; M610-V613 HydrophobicContact SD-CG2 4.36Å; V611-V613 VanDerWaalsContact C-N 3.34Å; V611-V613 PolarHBondContact O-N 3.02Å; V613-R615 VanDerWaalsContact C-N 3.34Å; V613-I616 PolarHBondContact O-N 3.16Å; V613-I617 HydrophobicContact CG1-CD1 3.79Å; V613-I617 HydrophobicContact CG1-CG1 4.35Å; V613-I617 VanDerWaalsContact O-CG1 3.31Å; V613-I617 WeakPolarHBondContact O-CG1 3.43Å; V613-I617 PolarHBondContact O-N 3.38Å
614E85.7Confident82.9Confident26 Ų2647.6 Ų47.612%0.12124%0.242CC..Hα-helixtrans-57-49.4174.7-167.7153.7-12700110.7S375 T378 M610 V611 I616 I617 E618S375-E614 PolarHBondContact N-OE1 3.48Å; T378-E614 HydrophobicContact CG2-CB 3.83Å; T378-E614 HydrophobicContact CG2-CG 4.34Å; T378-E614 PolarHBondContact OG1-OE1 2.99Å; M610-E614 PolarHBondContact O-N 3.32Å; V611-E614 WeakPolarHBondContact O-CB 3.48Å; V611-E614 PolarHBondContact O-N 3.2Å; E614-I616 PolarHBondContact O-N 3.1Å; E614-I617 CarbonylContact O-C 3.55Å; E614-I617 WeakPolarHBondContact O-CA 3.43Å; E614-I617 WeakPolarHBondContact O-CB 3.46Å; E614-I617 PolarHBondContact O-N 3.45Å; E614-E618 WeakPolarHBondContact O-CG 3.44Å; E614-E618 PolarHBondContact O-N 3.44Å
615R84.5Confident83.8Confident31 Ų3145.1 Ų45.112%0.11723%0.225CC..Hα-helixtrans-58.5-42.2174.3-64.5-64.9-168.9-147-0.9113.2E369 Y511 V611 V613 I617 E618 Y619E369-R615 PolarHBondContact O-NH2 2.92Å; Y511-R615 HydrophobicContact CD1-CB 4.23Å; Y511-R615 HydrophobicContact CD1-CG 4.47Å; Y511-R615 HydrophobicContact CD2-CB 3.74Å; Y511-R615 HydrophobicContact CE1-CB 4.07Å; Y511-R615 HydrophobicContact CE1-CG 3.88Å; Y511-R615 HydrophobicContact CE2-CB 3.53Å; Y511-R615 HydrophobicContact CE2-CG 3.9Å; Y511-R615 HydrophobicContact CG-CB 4.08Å; V611-R615 WeakPolarHBondContact O-CG 3.48Å; V611-R615 PolarHBondContact O-N 3.31Å; V611-R615 VanDerWaalsContact O-N 3.17Å; V613-R615 VanDerWaalsContact C-N 3.34Å; R615-I617 VanDerWaalsContact C-N 3.3Å; R615-I617 PolarHBondContact O-N 2.99Å; R615-E618 VanDerWaalsContact CD-OE2 3.29Å; R615-E618 WeakPolarHBondContact CD-OE2 3.33Å; R615-E618 IonicContact CZ-OE2 2.7Å; R615-E618 IonicContact NH1-OE1 2.9Å; R615-E618 IonicContact NH1-OE2 3.28Å; R615-E618 PolarHBondContact NH1-OE2 3.41Å; R615-E618 WeakPolarHBondContact O-CB 3.5Å; R615-E618 PolarHBondContact O-N 3.48Å; R615-Y619 WeakPolarHBondContact O-CD2 3.46Å; R615-Y619 PolarHBondContact O-N 2.88Å
616I87.3Confident84.6Confident2 Ų243.1 Ų43.11%0.0122%0.222CC..Hα-helixtrans-63.6-37.5175.3-71.4171.2000111.6L484 M488 L515 S612 V613 E614 Y619 G620L484-I616 HydrophobicContact CB-CG2 4.26Å; M488-I616 HydrophobicContact CB-CG2 3.77Å; M488-I616 HydrophobicContact CG-CG2 4Å; L515-I616 HydrophobicContact CB-CD1 3.66Å; L515-I616 HydrophobicContact CD1-CD1 4.46Å; L515-I616 HydrophobicContact CD2-CD1 3.8Å; L515-I616 HydrophobicContact CG-CD1 4.17Å; S612-I616 VanDerWaalsContact O-CG1 3.26Å; S612-I616 WeakPolarHBondContact O-CG1 3.45Å; S612-I616 PolarHBondContact O-N 2.85Å; S612-I616 VanDerWaalsContact O-N 3.08Å; V613-I616 PolarHBondContact O-N 3.16Å; E614-I616 PolarHBondContact O-N 3.1Å; I616-Y619 PolarHBondContact O-N 2.75Å; I616-G620 PolarHBondContact O-N 2.91Å
617I89.2Confident85.4Confident17 Ų1749.6 Ų49.69%0.08725%0.252CS..Hα-helixtrans-70.6-37.8176.9-70.6167.2000110.9T378 T381 L484 V613 E614 R615 G620 K621T378-I617 HydrophobicContact CG2-CD1 4.06Å; T381-I617 HydrophobicContact CG2-CD1 3.76Å; T381-I617 HydrophobicContact CG2-CG1 4.26Å; T381-I617 HydrophobicContact CG2-CG2 4.49Å; L484-I617 HydrophobicContact CD2-CG1 3.99Å; V613-I617 HydrophobicContact CG1-CD1 3.79Å; V613-I617 HydrophobicContact CG1-CG1 4.35Å; V613-I617 VanDerWaalsContact O-CG1 3.31Å; V613-I617 WeakPolarHBondContact O-CG1 3.43Å; V613-I617 PolarHBondContact O-N 3.38Å; E614-I617 CarbonylContact O-C 3.55Å; E614-I617 WeakPolarHBondContact O-CA 3.43Å; E614-I617 WeakPolarHBondContact O-CB 3.46Å; E614-I617 PolarHBondContact O-N 3.45Å; R615-I617 VanDerWaalsContact C-N 3.3Å; R615-I617 PolarHBondContact O-N 2.99Å; I617-G620 CarbonylContact O-C 3.51Å; I617-G620 WeakPolarHBondContact O-CA 3.22Å; I617-G620 PolarHBondContact O-N 2.62Å; I617-K621 WeakPolarHBondContact O-CG 3.42Å; I617-K621 PolarHBondContact O-N 2.87Å
618E87.5Confident85.9Confident68 Ų6847.8 Ų47.832%0.31824%0.244SC..Hα-helixtrans-58.8-48.4171.6-72.8170.4-174.900110.6E614 R615 G620 K621 L622E614-E618 WeakPolarHBondContact O-CG 3.44Å; E614-E618 PolarHBondContact O-N 3.44Å; R615-E618 VanDerWaalsContact CD-OE2 3.29Å; R615-E618 WeakPolarHBondContact CD-OE2 3.33Å; R615-E618 IonicContact CZ-OE2 2.7Å; R615-E618 IonicContact NH1-OE1 2.9Å; R615-E618 IonicContact NH1-OE2 3.28Å; R615-E618 PolarHBondContact NH1-OE2 3.41Å; R615-E618 WeakPolarHBondContact O-CB 3.5Å; R615-E618 PolarHBondContact O-N 3.48Å; E618-G620 VanDerWaalsContact C-N 3.26Å; E618-G620 PolarHBondContact O-N 2.9Å; E618-K621 WeakPolarHBondContact O-CA 3.4Å; E618-K621 WeakPolarHBondContact O-CB 3.21Å; E618-K621 PolarHBondContact O-N 3.15Å; E618-L622 PolarHBondContact O-N 3.39Å
619Y88.2Confident86.6Confident19 Ų1947 Ų478%0.07524%0.244CC..Hα-helixtrans-62.9-32.5174.3-66-30.5000113.2M488 H491 F499 I508 Y511 R615 I616 K621 L622M488-Y619 HydrophobicContact CG-CD2 4.39Å; H491-Y619 VanDerWaalsContact CB-O 3.27Å; H491-Y619 WeakPolarHBondContact CB-O 3.4Å; F499-Y619 HydrophobicContact CE2-CD1 4.12Å; F499-Y619 AromaticContact CE2-CE1 3.94Å; F499-Y619 HydrophobicContact CE2-CE1 3.94Å; F499-Y619 AromaticContact CZ-CD1 3.98Å; F499-Y619 HydrophobicContact CZ-CD1 3.98Å; F499-Y619 AromaticContact CZ-CE1 3.85Å; F499-Y619 HydrophobicContact CZ-CE1 3.85Å; I508-Y619 HydrophobicContact CB-CE2 4.42Å; I508-Y619 HydrophobicContact CG1-CD2 4.43Å; I508-Y619 HydrophobicContact CG1-CE2 3.74Å; Y511-Y619 HydrophobicContact CD2-CD2 4.41Å; Y511-Y619 AromaticContact CD2-CE2 3.67Å; Y511-Y619 HydrophobicContact CD2-CE2 3.67Å; Y511-Y619 AromaticContact CE2-CE2 3.69Å; Y511-Y619 HydrophobicContact CE2-CE2 3.69Å; R615-Y619 WeakPolarHBondContact O-CD2 3.46Å; R615-Y619 PolarHBondContact O-N 2.88Å; I616-Y619 PolarHBondContact O-N 2.75Å; Y619-K621 PolarHBondContact O-N 3.46Å; Y619-K621 VanDerWaalsContact O-N 3.15Å; Y619-L622 HydrophobicContact CD1-CD1 3.95Å; Y619-L622 HydrophobicContact CD1-CD2 4.5Å; Y619-L622 HydrophobicContact CD1-CG 4.37Å; Y619-L622 HydrophobicContact CG-CD1 4.42Å; Y619-L622 WeakPolarHBondContact O-CD1 3.31Å; Y619-L622 WeakPolarHBondContact O-CG 3.29Å; Y619-L622 PolarHBondContact O-N 3.19Å
620G87.7Confident87Confident4 Ų445.8 Ų45.84%0.04124%0.24CC..THydrogen-bonded Turntrans-69.3-0.1171.600000115.2H491 I616 I617 E618H491-G620 PolarHBondContact CD2-O 3.13Å; H491-G620 PolarHBondContact NE2-O 3.43Å; I616-G620 PolarHBondContact O-N 2.91Å; I617-G620 CarbonylContact O-C 3.51Å; I617-G620 WeakPolarHBondContact O-CA 3.22Å; I617-G620 PolarHBondContact O-N 2.62Å; E618-G620 VanDerWaalsContact C-N 3.26Å; E618-G620 PolarHBondContact O-N 2.9Å
621K87.9Confident87.1Confident149 Ų14950.4 Ų50.465%0.64828%0.279SS*.THydrogen-bonded Turntrans-122.87.8176.3-65171.8-174.6170.70113I617 E618 Y619I617-K621 WeakPolarHBondContact O-CG 3.42Å; I617-K621 PolarHBondContact O-N 2.87Å; E618-K621 WeakPolarHBondContact O-CA 3.4Å; E618-K621 WeakPolarHBondContact O-CB 3.21Å; E618-K621 PolarHBondContact O-N 3.15Å; Y619-K621 PolarHBondContact O-N 3.46Å; Y619-K621 VanDerWaalsContact O-N 3.15Å
622L87.7Confident87.3Confident30 Ų3054.5 Ų54.516%0.15730%0.298CS..PPolyproline II helixtrans-54.5142.6178.5-74.4165.9000111.2V492 A495 F499 E618 Y619 K624V492-L622 HydrophobicContact CG2-CD1 4.08Å; A495-L622 HydrophobicContact CB-CD1 4.33Å; F499-L622 HydrophobicContact CD1-CD1 4.48Å; F499-L622 HydrophobicContact CD2-CD1 3.99Å; F499-L622 HydrophobicContact CD2-CD2 3.77Å; F499-L622 HydrophobicContact CE1-CD1 4.08Å; F499-L622 HydrophobicContact CE2-CD1 3.54Å; F499-L622 HydrophobicContact CE2-CD2 3.64Å; F499-L622 HydrophobicContact CE2-CG 4.25Å; F499-L622 HydrophobicContact CG-CD1 4.45Å; F499-L622 HydrophobicContact CZ-CD1 3.59Å; E618-L622 PolarHBondContact O-N 3.39Å; Y619-L622 HydrophobicContact CD1-CD1 3.95Å; Y619-L622 HydrophobicContact CD1-CD2 4.5Å; Y619-L622 HydrophobicContact CD1-CG 4.37Å; Y619-L622 HydrophobicContact CG-CD1 4.42Å; Y619-L622 WeakPolarHBondContact O-CD1 3.31Å; Y619-L622 WeakPolarHBondContact O-CG 3.29Å; Y619-L622 PolarHBondContact O-N 3.19Å; L622-K624 PolarHBondContact O-N 2.92Å
623P86.5Confident87.3Confident106 Ų10657.9 Ų57.969%0.68832%0.32SS*.PPolyproline II helixtrans-60.5127.7171.827-33000108.5
624K87.5Confident87.1Confident96 Ų9659.7 Ų59.742%0.41733%0.332SS..BIsolated β-bridgetrans-82151.7176.7-59.8179.5-175.4179.60109.1H491 R494 L622H491-K624 WeakPolarHBondContact CD2-CE 3.28Å; H491-K624 WeakPolarHBondContact NE2-CE 3.44Å; H491-K624 PolarHBondContact NE2-NZ 3.3Å; R494-K624 HydrophobicContact CB-CB 4.44Å; R494-K624 HydrophobicContact CB-CG 4.28Å; L622-K624 PolarHBondContact O-N 2.92Å
625E90.3Very high87.1Confident21 Ų2164.6 Ų64.610%0.09836%0.359CS..PPolyproline II helixtrans-57.7169.5161.9-69.4178.7-170.900110.8K27 R494 A495 S496 L713 R717K27-E625 WeakPolarHBondContact CD-OE1 2.84Å; K27-E625 VanDerWaalsContact CE-OE1 3.27Å; K27-E625 WeakPolarHBondContact CE-OE1 3.35Å; K27-E625 VanDerWaalsContact NZ-CD 3.32Å; K27-E625 IonicContact NZ-OE1 3.14Å; K27-E625 PolarHBondContact NZ-OE1 3.03Å; K27-E625 IonicContact NZ-OE2 3.87Å; R494-E625 PolarHBondContact NH2-O 3.19Å; R494-E625 PolarHBondContact O-N 2.8Å; A495-E625 VanDerWaalsContact O-OE1 3.12Å; S496-E625 WeakPolarHBondContact CA-OE1 3.43Å; E625-L713 HydrophobicContact CB-CD1 3.73Å; E625-R717 IonicContact OE2-CZ 2.72Å; E625-R717 IonicContact OE2-NH1 2.75Å; E625-R717 PolarHBondContact OE2-NH1 3.05Å; E625-R717 VanDerWaalsContact OE2-NH1 3.14Å; E625-R717 IonicContact OE2-NH2 3.03Å; E625-R717 PolarHBondContact OE2-NH2 2.89Å
626A89.3Confident87Confident32 Ų3272 Ų7226%0.26440%0.395SS..SBendtrans-46.6157.9171.300000112.8R494 E696 L713R494-A626 PolarHBondContact NH1-O 3.32Å; R494-A626 VanDerWaalsContact NH1-O 3.1Å; R494-A626 PolarHBondContact NH2-O 3.49Å; A626-E696 WeakPolarHBondContact CB-OE1 3.09Å; A626-L713 HydrophobicContact CB-CD1 3.99Å; A626-L713 HydrophobicContact CB-CD2 4.24Å; A626-L713 HydrophobicContact CB-CG 4.05Å; A626-L713 WeakPolarHBondContact O-CD1 3.41Å
627E90.8Very high86.9Confident137 Ų13776.1 Ų76.164%0.6442%0.424SS*.PPolyproline II helixtrans-58.5144.3-177.1-69.7-61.4164.300111.9R494 T629 G712 L713R494-E627 IonicContact NH2-OE2 3.14Å; E627-T629 VanDerWaalsContact C-N 3.31Å; E627-G712 WeakPolarHBondContact O-CA 3.38Å; E627-L713 PolarHBondContact O-N 3.41Å
628L88.8Confident87Confident39 Ų3976.2 Ų76.220%0.20442%0.423CS..SBendtrans-71.2-30.9-176.9-66.4178.6000112.3R494 G712 L713 H714R494-L628 VanDerWaalsContact CZ-CD2 3.48Å; R494-L628 VanDerWaalsContact CZ-CG 3.4Å; L628-G712 CarbonylContact O-C 3.58Å; L628-G712 VanDerWaalsContact O-C 3.26Å; L628-G712 WeakPolarHBondContact O-CA 3.18Å; L628-L713 HydrophobicContact CD2-CB 4.44Å; L628-L713 PolarHBondContact O-N 2.95Å; L628-H714 WeakPolarHBondContact CD2-NE2 3.43Å; L628-H714 WeakPolarHBondContact O-CB 3.47Å; L628-H714 PolarHBondContact O-N 2.95Å
629T88.9Confident87.2Confident92 Ų9273.5 Ų73.556%0.56441%0.411SS*.SBendtrans-126.8141.3-17751.90000109.1E627 E715E627-T629 VanDerWaalsContact C-N 3.31Å; T629-E715 WeakPolarHBondContact CA-OE1 3.4Å
630S87.5Confident87.2Confident25 Ų2575.6 Ų75.618%0.17543%0.429CS..  trans-87164.9174.364.40000111.1N632 P633 T710 E715S630-N632 VanDerWaalsContact C-N 3.31Å; S630-N632 PolarHBondContact OG-O 3.33Å; S630-P633 WeakPolarHBondContact OG-CA 3.22Å; S630-T710 WeakPolarHBondContact CB-O 3.41Å; S630-E715 WeakPolarHBondContact CB-OE2 3.42Å; S630-E715 PolarHBondContact N-OE1 3.37Å; S630-E715 PolarHBondContact N-OE2 3.03Å; S630-E715 PolarHBondContact OG-OE1 2.74Å; S630-E715 PolarHBondContact OG-OE2 3.46Å
631A83.8Confident87.3Confident98 Ų9881.1 Ų81.181%0.8145%0.453SS*.SBendtrans-70.4-31.2172.100000112
632N84.8Confident87.5Confident146 Ų14674 Ų7478%0.78142%0.423SS*.SBendtrans-127.780.7-177.9-66.4-18.1000109S630S630-N632 VanDerWaalsContact C-N 3.31Å; S630-N632 PolarHBondContact OG-O 3.33Å
633P83.6Confident87.9Confident78 Ų7875 Ų7551%0.50643%0.426SS..PPolyproline II helixtrans-64.9146.8178.227.4-34.2000110.4S630S630-P633 WeakPolarHBondContact OG-CA 3.22Å
634P82.1Confident88.4Confident38 Ų3870.2 Ų70.225%0.24740%0.395CS..PPolyproline II helixtrans-69162.2172.731-34.1000110.2W638 L711P634-W638 HydrophobicContact CB-CB 3.85Å; P634-W638 HydrophobicContact CB-CD2 3.99Å; P634-W638 HydrophobicContact CB-CE3 4.27Å; P634-W638 HydrophobicContact CB-CG 3.82Å; P634-W638 HydrophobicContact CG-CB 4.31Å; P634-W638 HydrophobicContact CG-CD2 3.85Å; P634-W638 HydrophobicContact CG-CE3 3.61Å; P634-W638 HydrophobicContact CG-CG 4.18Å; P634-W638 HydrophobicContact CG-CZ3 4.23Å; P634-L711 VanDerWaalsContact CD-CD2 3.5Å; P634-L711 HydrophobicContact CG-CD2 3.79Å
635D85.8Confident88.8Confident129 Ų12966.4 Ų66.469%0.6938%0.38SS*.PPolyproline II helixtrans-55.1151.7177.4-63.8-32.4000111.8S637 W638D635-S637 PolarHBondContact O-N 3.35Å; D635-W638 VanDerWaalsContact O-CB 3.26Å; D635-W638 WeakPolarHBondContact O-CB 3.46Å; D635-W638 PolarHBondContact O-N 3.41Å
636E83.1Confident89.1Confident185 Ų18565.6 Ų65.686%0.86438%0.376SS*.THydrogen-bonded Turntrans-58.1-27.4-177.5-68.4-171.2166.200113.6W638 K719E636-W638 VanDerWaalsContact C-N 3.28Å; E636-W638 PolarHBondContact O-N 3.36Å; E636-K719 PolarHBondContact O-NZ 2.92Å
637S85.2Confident89.4Confident90 Ų9069 Ų6963%0.62939%0.385SS*.THydrogen-bonded Turntrans-76.4-9.4176.856.10000114.2D635 P639 S640D635-S637 PolarHBondContact O-N 3.35Å; S637-P639 CarbonylContact O-C 3.47Å; S637-S640 PolarHBondContact O-N 2.95Å
638W90.8Very high89.6Confident19 Ų1967.3 Ų67.37%0.07238%0.38CS..  trans-74.7139.1175.6-179.191.5000110.8P634 D635 E636 I703 V706 L711 L716 K719P634-W638 HydrophobicContact CB-CB 3.85Å; P634-W638 HydrophobicContact CB-CD2 3.99Å; P634-W638 HydrophobicContact CB-CE3 4.27Å; P634-W638 HydrophobicContact CB-CG 3.82Å; P634-W638 HydrophobicContact CG-CB 4.31Å; P634-W638 HydrophobicContact CG-CD2 3.85Å; P634-W638 HydrophobicContact CG-CE3 3.61Å; P634-W638 HydrophobicContact CG-CG 4.18Å; P634-W638 HydrophobicContact CG-CZ3 4.23Å; D635-W638 VanDerWaalsContact O-CB 3.26Å; D635-W638 WeakPolarHBondContact O-CB 3.46Å; D635-W638 PolarHBondContact O-N 3.41Å; E636-W638 VanDerWaalsContact C-N 3.28Å; E636-W638 PolarHBondContact O-N 3.36Å; W638-I703 HydrophobicContact CH2-CB 4.29Å; W638-I703 HydrophobicContact CH2-CG2 4.2Å; W638-I703 HydrophobicContact CZ2-CB 3.67Å; W638-I703 HydrophobicContact CZ2-CG2 3.65Å; W638-I703 PolarHBondContact NE1-O 3.25Å; W638-I703 VanDerWaalsContact NE1-O 3.09Å; W638-V706 HydrophobicContact CZ2-CB 4.14Å; W638-V706 HydrophobicContact CZ2-CG1 4.49Å; W638-L711 HydrophobicContact CH2-CD1 3.15Å; W638-L711 HydrophobicContact CZ2-CD1 3.55Å; W638-L711 HydrophobicContact CZ3-CD1 3.81Å; W638-L716 HydrophobicContact CH2-CD1 4.24Å; W638-K719 HydrophobicContact CE3-CG 4.23Å; W638-K719 HydrophobicContact CZ3-CB 4.23Å; W638-K719 HydrophobicContact CZ3-CG 4.16Å; W638-K719 VanDerWaalsContact O-CD 3.3Å; W638-K719 WeakPolarHBondContact O-CD 3.49Å; W638-K719 WeakPolarHBondContact O-CE 3.18Å; W638-K719 PolarHBondContact O-NZ 2.96Å
639P91.5Very high89.9Confident10 Ų1065.4 Ų65.47%0.06537%0.37CS..SBendcis-75.6139.2-1131.4-33.5000111.7S637 I703 D704 K719 R799 I800S637-P639 CarbonylContact O-C 3.47Å; P639-I703 HydrophobicContact CB-CG2 3.85Å; P639-I703 HydrophobicContact CG-CG2 4.36Å; P639-D704 WeakPolarHBondContact CA-OD2 3.15Å; P639-D704 WeakPolarHBondContact CB-OD2 3.13Å; P639-K719 HydrophobicContact CG-CB 4.43Å; P639-R799 HydrophobicContact CG-CB 4.43Å; P639-R799 WeakPolarHBondContact O-CG 3.35Å; P639-I800 HydrophobicContact CG-CD1 4.26Å
640S88.8Confident90.2Very high63 Ų6361.6 Ų61.644%0.44135%0.347SS..SBendtrans-87.7-38.9-17850.40000112.5S637 D704S637-S640 PolarHBondContact O-N 2.95Å; S640-D704 PolarHBondContact N-OD2 3.18Å; S640-D704 PolarHBondContact OG-OD2 3.4Å
641H89.8Confident90.4Very high121 Ų12160.4 Ų60.456%0.5634%0.339SS*.SBendtrans-107.7-35.3-175.4-59.968000111.6P670 D704H641-P670 HydrophobicContact CB-CB 3.99Å; H641-P670 HydrophobicContact CB-CG 3.74Å; H641-P670 WeakPolarHBondContact O-CB 3.44Å; H641-D704 PolarHBondContact N-OD2 3.2Å
642G91.3Very high90.6Very high0 Ų059.7 Ų59.70%032%0.315CS..  trans82.531.8-178.300000113.1D704 S830G642-D704 PolarHBondContact N-OD1 3.08Å; G642-D704 PolarHBondContact N-OD2 3.27Å; G642-S830 VanDerWaalsContact O-CB 3.27Å; G642-S830 WeakPolarHBondContact O-CB 3.14Å; G642-S830 PolarHBondContact O-OG 2.82Å
643E95.8Very high90.3Very high51 Ų5156.1 Ų56.124%0.23829%0.291CS..  trans-74.6133.8170-173.9178.7-129.700109.9V645 T667 L668 P670 I703 D704E643-V645 HydrophobicContact CG-CG2 4.08Å; E643-T667 HydrophobicContact CG-CG2 4.34Å; E643-L668 WeakPolarHBondContact CA-O 3.44Å; E643-P670 HydrophobicContact CB-CG 4.02Å; E643-I703 CarbonylContact O-C 3.46Å; E643-I703 VanDerWaalsContact O-CA 3.24Å; E643-I703 WeakPolarHBondContact O-CA 3.49Å; E643-D704 PolarHBondContact N-OD1 3.44Å; E643-D704 PolarHBondContact O-N 2.96Å
644V96.5Very high90Very high4 Ų453.8 Ų53.82%0.02428%0.277CS..EExtended strand (participates in β ladder)trans-125.3123.1175-171.70000110F646 T667 L668 L691 I701 Y702 I703 I800V644-F646 HydrophobicContact CG1-CD2 4.07Å; V644-F646 HydrophobicContact CG1-CE2 3.75Å; V644-T667 CarbonylContact O-C 3.59Å; V644-T667 WeakPolarHBondContact O-CA 3.31Å; V644-L668 HydrophobicContact CB-CB 4.05Å; V644-L668 HydrophobicContact CB-CD2 4.35Å; V644-L668 HydrophobicContact CG2-CD2 4.04Å; V644-L668 PolarHBondContact N-O 3.23Å; V644-L668 PolarHBondContact O-N 3.08Å; V644-L691 HydrophobicContact CG1-CD1 3.87Å; V644-I701 HydrophobicContact CG1-CG2 4.27Å; V644-Y702 CarbonylContact C-O 3.53Å; V644-Y702 WeakPolarHBondContact CA-O 3.27Å; V644-I703 HydrophobicContact CG1-CG1 4.24Å; V644-I703 HydrophobicContact CG2-CG1 4.21Å; V644-I800 HydrophobicContact CG2-CD1 3.7Å; V644-I800 HydrophobicContact CG2-CG1 4.32Å; V644-I800 HydrophobicContact CG2-CG2 4.39Å
645V97.1Very high89.8Confident17 Ų1755.5 Ų55.510%0.10329%0.294CS..EExtended strand (participates in β ladder)trans-120.5116.7-177.8-171.40000110.4E643 K647 T667 I701 Y702E643-V645 HydrophobicContact CG-CG2 4.08Å; V645-K647 HydrophobicContact CG1-CD 4.48Å; V645-K647 HydrophobicContact CG1-CG 3.9Å; V645-T667 HydrophobicContact CG2-CG2 3.99Å; V645-I701 CarbonylContact O-C 3.5Å; V645-I701 WeakPolarHBondContact O-CA 3.44Å; V645-Y702 PolarHBondContact N-O 3.43Å; V645-Y702 PolarHBondContact O-N 3.31Å
646F96.7Very high89.3Confident4 Ų457 Ų572%0.01830%0.302CS..EExtended strand (participates in β ladder)trans-91.8124.7169.4-79.7-118000109V644 V649 S665 F666 V687 A690 L691 I701V644-F646 HydrophobicContact CG1-CD2 4.07Å; V644-F646 HydrophobicContact CG1-CE2 3.75Å; F646-V649 HydrophobicContact CB-CG2 4.09Å; F646-V649 HydrophobicContact CD1-CB 3.9Å; F646-V649 HydrophobicContact CD1-CG1 4.12Å; F646-V649 HydrophobicContact CD1-CG2 3.64Å; F646-V649 HydrophobicContact CE1-CG1 4.35Å; F646-V649 HydrophobicContact CE1-CG2 4.46Å; F646-V649 HydrophobicContact CG-CG2 4.19Å; F646-S665 VanDerWaalsContact O-CA 3.25Å; F646-S665 WeakPolarHBondContact O-CA 3.46Å; F646-F666 HydrophobicContact CB-CD1 3.88Å; F646-F666 HydrophobicContact CB-CE1 3.89Å; F646-F666 HydrophobicContact CB-CG 4.36Å; F646-F666 HydrophobicContact CB-CZ 4.38Å; F646-F666 AromaticContact CD1-CE1 3.73Å; F646-F666 HydrophobicContact CD1-CE1 3.73Å; F646-F666 HydrophobicContact CD1-CZ 4.11Å; F646-F666 HydrophobicContact CD2-CD1 4.39Å; F646-F666 HydrophobicContact CD2-CD2 4.46Å; F646-F666 AromaticContact CD2-CE1 3.71Å; F646-F666 HydrophobicContact CD2-CE1 3.71Å; F646-F666 AromaticContact CD2-CE2 3.79Å; F646-F666 HydrophobicContact CD2-CE2 3.79Å; F646-F666 AromaticContact CD2-CZ 3.36Å; F646-F666 HydrophobicContact CD2-CZ 3.36Å; F646-F666 HydrophobicContact CE1-CE1 4.18Å; F646-F666 HydrophobicContact CE1-CZ 4.25Å; F646-F666 HydrophobicContact CE2-CE1 4.15Å; F646-F666 HydrophobicContact CE2-CE2 4.11Å; F646-F666 AromaticContact CE2-CZ 3.53Å; F646-F666 HydrophobicContact CE2-CZ 3.53Å; F646-F666 HydrophobicContact CG-CD1 4.03Å; F646-F666 AromaticContact CG-CE1 3.49Å; F646-F666 HydrophobicContact CG-CE1 3.49Å; F646-F666 VanDerWaalsContact CG-CE1 3.49Å; F646-F666 HydrophobicContact CG-CE2 4.38Å; F646-F666 AromaticContact CG-CZ 3.7Å; F646-F666 HydrophobicContact CG-CZ 3.7Å; F646-F666 HydrophobicContact CZ-CE1 4.38Å; F646-F666 AromaticContact CZ-CZ 3.99Å; F646-F666 HydrophobicContact CZ-CZ 3.99Å; F646-F666 PolarHBondContact N-O 3.08Å; F646-F666 PolarHBondContact O-N 3.32Å; F646-F666 VanDerWaalsContact O-N 3.15Å; F646-V687 HydrophobicContact CE1-CG1 4.09Å; F646-V687 HydrophobicContact CZ-CG1 4.03Å; F646-A690 HydrophobicContact CE1-CB 4.45Å; F646-L691 HydrophobicContact CE2-CD1 4.17Å; F646-L691 HydrophobicContact CZ-CB 4.15Å; F646-L691 HydrophobicContact CZ-CD1 4.26Å; F646-I701 HydrophobicContact CD1-CD1 4.2Å; F646-I701 HydrophobicContact CD1-CG1 4.08Å; F646-I701 HydrophobicContact CD2-CG2 4.29Å; F646-I701 HydrophobicContact CE1-CD1 3.69Å; F646-I701 HydrophobicContact CE1-CG1 4.07Å; F646-I701 HydrophobicContact CE2-CG2 4.08Å; F646-I701 HydrophobicContact CG-CG1 4.33Å; F646-I701 HydrophobicContact CZ-CD1 3.89Å; F646-I701 HydrophobicContact CZ-CG1 4.32Å; F646-I701 HydrophobicContact CZ-CG2 4.41Å
647K95.3Very high88.9Confident103 Ų10349.4 Ų49.445%0.44827%0.27SS..EExtended strand (participates in β ladder)trans-123.6108.9175.8-62.1-169.6-175.9171.60110.6V645 V649 Q700 Y702V645-K647 HydrophobicContact CG1-CD 4.48Å; V645-K647 HydrophobicContact CG1-CG 3.9Å; K647-V649 VanDerWaalsContact C-N 3.29Å; K647-V649 PolarHBondContact O-N 3.35Å; K647-Q700 PolarHBondContact N-O 3.1Å; K647-Q700 PolarHBondContact O-N 3.39Å; K647-Y702 HydrophobicContact CD-CD2 4.23Å; K647-Y702 HydrophobicContact CD-CE2 3.86Å; K647-Y702 HydrophobicContact CG-CD2 4.47Å; K647-Y702 HydrophobicContact CG-CE2 4.41Å
648N94.8Very high88.7Confident101 Ų10149.8 Ų49.854%0.5427%0.27SS..EExtended strand (participates in β ladder)trans49.646.6177.1-60.5-30.5000112.9S650 S665N648-S650 PolarHBondContact O-N 2.89Å; N648-S665 WeakPolarHBondContact CA-OG 3.19Å; N648-S665 PolarHBondContact N-OG 3.42Å; N648-S665 PolarHBondContact OD1-OG 2.98Å; N648-S665 VanDerWaalsContact OD1-OG 3.1Å
649V95.1Very high88.5Confident0 Ų052.7 Ų52.70%028%0.281CS..EExtended strand (participates in β ladder)trans-77.9125.1-174.71750000110.6F646 K647 N663 V664 A690 P697 E698 I701F646-V649 HydrophobicContact CB-CG2 4.09Å; F646-V649 HydrophobicContact CD1-CB 3.9Å; F646-V649 HydrophobicContact CD1-CG1 4.12Å; F646-V649 HydrophobicContact CD1-CG2 3.64Å; F646-V649 HydrophobicContact CE1-CG1 4.35Å; F646-V649 HydrophobicContact CE1-CG2 4.46Å; F646-V649 HydrophobicContact CG-CG2 4.19Å; K647-V649 VanDerWaalsContact C-N 3.29Å; K647-V649 PolarHBondContact O-N 3.35Å; V649-N663 PolarHBondContact O-N 2.92Å; V649-V664 PolarHBondContact N-O 2.92Å; V649-V664 PolarHBondContact O-N 2.86Å; V649-A690 HydrophobicContact CG1-CB 4.31Å; V649-P697 HydrophobicContact CG1-CB 3.86Å; V649-E698 CarbonylContact C-O 3.5Å; V649-E698 VanDerWaalsContact CA-O 3.27Å; V649-E698 WeakPolarHBondContact CA-O 3.21Å; V649-I701 HydrophobicContact CG1-CD1 4.48Å; V649-I701 HydrophobicContact CG2-CD1 4.32Å; V649-I701 HydrophobicContact CG2-CG1 3.66Å
650S94Very high88.3Confident11 Ų1154.8 Ų54.88%0.07729%0.291CS..EExtended strand (participates in β ladder)trans-124.3143.7173.8-62.20000109.9N648 L661 N663 E698N648-S650 PolarHBondContact O-N 2.89Å; S650-L661 WeakPolarHBondContact CA-O 3.34Å; S650-L661 WeakPolarHBondContact CB-O 3.41Å; S650-N663 PolarHBondContact OG-N 3.3Å; S650-N663 PolarHBondContact OG-OD1 2.96Å; S650-E698 PolarHBondContact N-O 3.47Å; S650-E698 PolarHBondContact O-N 3.47Å
651L91.7Very high88.5Confident1 Ų151.8 Ų51.81%0.00527%0.271CS..EExtended strand (participates in β ladder)trans-138.4134.5-175.2-167.380.4000111.1Y659 I660 L661 T689 A690 V695 P697L651-Y659 WeakPolarHBondContact O-CA 3.4Å; L651-I660 PolarHBondContact O-N 3.05Å; L651-L661 HydrophobicContact CB-CB 3.98Å; L651-L661 HydrophobicContact CB-CD1 4.05Å; L651-L661 HydrophobicContact CB-CG 4.16Å; L651-L661 HydrophobicContact CD2-CD1 4.45Å; L651-L661 PolarHBondContact N-O 2.84Å; L651-L661 PolarHBondContact O-N 3.39Å; L651-T689 HydrophobicContact CD2-CG2 4.16Å; L651-A690 HydrophobicContact CD1-CB 4.33Å; L651-V695 HydrophobicContact CD1-CB 4.08Å; L651-V695 HydrophobicContact CD1-CG1 3.97Å; L651-P697 HydrophobicContact CD1-CB 4.09Å
652R88.1Confident88.6Confident82 Ų8251.6 Ų51.631%0.30927%0.265SS..  trans-136.1142.6170.558.2-179.9167.2168.4-8.4109.2S654 A655 Y659 V695 E698R652-S654 WeakPolarHBondContact CD-O 3.37Å; R652-A655 PolarHBondContact NH1-O 2.82Å; R652-Y659 HydrophobicContact CB-CD1 4.13Å; R652-Y659 HydrophobicContact CB-CE1 4.32Å; R652-Y659 HydrophobicContact CG-CD1 4.33Å; R652-Y659 HydrophobicContact CG-CE1 4.02Å; R652-V695 WeakPolarHBondContact O-CG1 3.36Å; R652-E698 IonicContact CZ-OE1 3.13Å; R652-E698 IonicContact NE-OE1 3.32Å; R652-E698 PolarHBondContact NE-OE1 3.02Å; R652-E698 IonicContact NH2-OE1 2.7Å; R652-E698 PolarHBondContact NH2-OE1 2.86Å
653Y79.4Confident88.7Confident72 Ų7257 Ų5728%0.28229%0.293SS..SBendtrans-80.3-22.6-179.2-76.1-78.3000113V498 S657 I660 T689 V695V498-Y653 HydrophobicContact CG2-CD1 3.96Å; V498-Y653 WeakPolarHBondContact CG2-O 3.28Å; Y653-S657 PolarHBondContact N-OG 3.26Å; Y653-I660 HydrophobicContact CD2-CD1 3.27Å; Y653-I660 HydrophobicContact CE2-CD1 3.37Å; Y653-T689 HydrophobicContact CE1-CG2 4.08Å; Y653-V695 HydrophobicContact CD1-CG2 3.72Å; Y653-V695 HydrophobicContact CE1-CG2 3.88Å
654S78.1Confident88.6Confident29 Ų2954.6 Ų54.620%0.20328%0.283CS..SBendtrans-145.7161171.252.80000111.6R502 R652 D656 S657R502-S654 PolarHBondContact NH2-OG 3.34Å; R652-S654 WeakPolarHBondContact CD-O 3.37Å; S654-D656 PolarHBondContact O-N 3.11Å; S654-S657 PolarHBondContact N-OG 3.37Å; S654-S657 PolarHBondContact O-N 3.25Å; S654-S657 PolarHBondContact O-OG 3.12Å; S654-S657 WeakPolarHBondContact OG-CB 3.18Å; S654-S657 PolarHBondContact OG-N 2.95Å; S654-S657 PolarHBondContact OG-OG 2.85Å
655A76.7Confident88.5Confident73 Ų7356.6 Ų56.660%0.60330%0.297SS*.THydrogen-bonded Turntrans-53.2-38.2177.500000112.2R652R652-A655 PolarHBondContact NH1-O 2.82Å
656D76.5Confident88.4Confident160 Ų16056.2 Ų56.286%0.85629%0.294SS*.THydrogen-bonded Turntrans-87.3-6.1-178.1-45-47.8000113.9S654S654-D656 PolarHBondContact O-N 3.11Å
657S74.1Confident88.4Confident27 Ų2758.1 Ų58.119%0.18931%0.306CS..SBendtrans-89.1147-179.9660000111.4Y653 S654Y653-S657 PolarHBondContact N-OG 3.26Å; S654-S657 PolarHBondContact N-OG 3.37Å; S654-S657 PolarHBondContact O-N 3.25Å; S654-S657 PolarHBondContact O-OG 3.12Å; S654-S657 WeakPolarHBondContact OG-CB 3.18Å; S654-S657 PolarHBondContact OG-N 2.95Å; S654-S657 PolarHBondContact OG-OG 2.85Å
658P81.4Confident88.4Confident97 Ų9753.4 Ų53.463%0.6329%0.285SS*.PPolyproline II helixtrans-62.3154.5174.327.7-35.1000111.6I660P658-I660 PolarHBondContact O-N 3.04Å
659Y86.3Confident88.4Confident80 Ų8053.8 Ų53.831%0.31428%0.282SS..PPolyproline II helixtrans-65.8122172-71.5-78.3000110.8L651 R652 R662 E698L651-Y659 WeakPolarHBondContact O-CA 3.4Å; R652-Y659 HydrophobicContact CB-CD1 4.13Å; R652-Y659 HydrophobicContact CB-CE1 4.32Å; R652-Y659 HydrophobicContact CG-CD1 4.33Å; R652-Y659 HydrophobicContact CG-CE1 4.02Å; Y659-R662 PolarHBondContact O-NE 3.17Å; Y659-E698 PolarHBondContact OH-OE1 3.36Å; Y659-E698 VanDerWaalsContact OH-OE1 3.09Å; Y659-E698 PolarHBondContact OH-OE2 3.14Å
660I87.6Confident88.3Confident54 Ų5456.8 Ų56.828%0.27730%0.301SS..SBendtrans-88.9-31.6176.6-64.4169.2000110.8L651 Y653 P658 S686 G853L651-I660 PolarHBondContact O-N 3.05Å; Y653-I660 HydrophobicContact CD2-CD1 3.27Å; Y653-I660 HydrophobicContact CE2-CD1 3.37Å; P658-I660 PolarHBondContact O-N 3.04Å; I660-S686 WeakPolarHBondContact CG2-OG 3.26Å; I660-G853 WeakPolarHBondContact O-CA 3.24Å
661L92.1Very high88.1Confident1 Ų157.8 Ų57.81%0.00531%0.314CS..EExtended strand (participates in β ladder)trans-114.2136.4165.9-62.1178.9000108.4S650 L651 V664 V687 G853S650-L661 WeakPolarHBondContact CA-O 3.34Å; S650-L661 WeakPolarHBondContact CB-O 3.41Å; L651-L661 HydrophobicContact CB-CB 3.98Å; L651-L661 HydrophobicContact CB-CD1 4.05Å; L651-L661 HydrophobicContact CB-CG 4.16Å; L651-L661 HydrophobicContact CD2-CD1 4.45Å; L651-L661 PolarHBondContact N-O 2.84Å; L651-L661 PolarHBondContact O-N 3.39Å; L661-V664 HydrophobicContact CB-CG2 4.19Å; L661-V664 HydrophobicContact CD2-CG2 4.27Å; L661-V687 HydrophobicContact CD1-CG2 4.11Å; L661-V687 HydrophobicContact CD2-CG2 4.23Å; L661-G853 WeakPolarHBondContact CA-O 3.15Å
662R92.2Very high88.2Confident117 Ų11758.4 Ų58.444%0.44232%0.317SS..EExtended strand (participates in β ladder)trans-130.4107.2-175.6-61.6177.3-173.2-178.71.7109.5Y659 V664 G853 Q854Y659-R662 PolarHBondContact O-NE 3.17Å; R662-V664 VanDerWaalsContact C-N 3.29Å; R662-V664 PolarHBondContact O-N 3.03Å; R662-G853 PolarHBondContact N-O 3.03Å; R662-Q854 HydrophobicContact CB-CG 4.01Å
663N92.5Very high88.4Confident112 Ų11256.7 Ų56.760%0.59931%0.311SS*.EExtended strand (participates in β ladder)trans51.241.7174.7-62.7-28.5000114.5V649 S650 S665V649-N663 PolarHBondContact O-N 2.92Å; S650-N663 PolarHBondContact OG-N 3.3Å; S650-N663 PolarHBondContact OG-OD1 2.96Å; N663-S665 PolarHBondContact O-N 3.24Å
664V93.6Very high89.1Confident2 Ų253.2 Ų53.21%0.01230%0.298CS..EExtended strand (participates in β ladder)trans-73.2123.7-179.8177.90000110.1V649 L661 R662 F666 G853 L855V649-V664 PolarHBondContact N-O 2.92Å; V649-V664 PolarHBondContact O-N 2.86Å; L661-V664 HydrophobicContact CB-CG2 4.19Å; L661-V664 HydrophobicContact CD2-CG2 4.27Å; R662-V664 VanDerWaalsContact C-N 3.29Å; R662-V664 PolarHBondContact O-N 3.03Å; V664-F666 HydrophobicContact CG1-CD1 3.84Å; V664-F666 HydrophobicContact CG1-CE1 3.98Å; V664-G853 WeakPolarHBondContact CG2-O 3.49Å; V664-L855 HydrophobicContact CG1-CB 4.49Å
665S95.5Very high89.8Confident46 Ų4651.9 Ų51.932%0.32229%0.288SS..EExtended strand (participates in β ladder)trans-133.2123179.5-63.50000111.2F646 N648 N663F646-S665 VanDerWaalsContact O-CA 3.25Å; F646-S665 WeakPolarHBondContact O-CA 3.46Å; N648-S665 WeakPolarHBondContact CA-OG 3.19Å; N648-S665 PolarHBondContact N-OG 3.42Å; N648-S665 PolarHBondContact OD1-OG 2.98Å; N648-S665 VanDerWaalsContact OD1-OG 3.1Å; N663-S665 PolarHBondContact O-N 3.24Å
666F95.4Very high90.6Very high9 Ų948.4 Ų48.44%0.03926%0.26CS..EExtended strand (participates in β ladder)trans-159.7168.9175.267.4-91.1000111.3F646 V664 L674 V687 I848 L855 Y858F646-F666 HydrophobicContact CB-CD1 3.88Å; F646-F666 HydrophobicContact CB-CE1 3.89Å; F646-F666 HydrophobicContact CB-CG 4.36Å; F646-F666 HydrophobicContact CB-CZ 4.38Å; F646-F666 AromaticContact CD1-CE1 3.73Å; F646-F666 HydrophobicContact CD1-CE1 3.73Å; F646-F666 HydrophobicContact CD1-CZ 4.11Å; F646-F666 HydrophobicContact CD2-CD1 4.39Å; F646-F666 HydrophobicContact CD2-CD2 4.46Å; F646-F666 AromaticContact CD2-CE1 3.71Å; F646-F666 HydrophobicContact CD2-CE1 3.71Å; F646-F666 AromaticContact CD2-CE2 3.79Å; F646-F666 HydrophobicContact CD2-CE2 3.79Å; F646-F666 AromaticContact CD2-CZ 3.36Å; F646-F666 HydrophobicContact CD2-CZ 3.36Å; F646-F666 HydrophobicContact CE1-CE1 4.18Å; F646-F666 HydrophobicContact CE1-CZ 4.25Å; F646-F666 HydrophobicContact CE2-CE1 4.15Å; F646-F666 HydrophobicContact CE2-CE2 4.11Å; F646-F666 AromaticContact CE2-CZ 3.53Å; F646-F666 HydrophobicContact CE2-CZ 3.53Å; F646-F666 HydrophobicContact CG-CD1 4.03Å; F646-F666 AromaticContact CG-CE1 3.49Å; F646-F666 HydrophobicContact CG-CE1 3.49Å; F646-F666 VanDerWaalsContact CG-CE1 3.49Å; F646-F666 HydrophobicContact CG-CE2 4.38Å; F646-F666 AromaticContact CG-CZ 3.7Å; F646-F666 HydrophobicContact CG-CZ 3.7Å; F646-F666 HydrophobicContact CZ-CE1 4.38Å; F646-F666 AromaticContact CZ-CZ 3.99Å; F646-F666 HydrophobicContact CZ-CZ 3.99Å; F646-F666 PolarHBondContact N-O 3.08Å; F646-F666 PolarHBondContact O-N 3.32Å; F646-F666 VanDerWaalsContact O-N 3.15Å; V664-F666 HydrophobicContact CG1-CD1 3.84Å; V664-F666 HydrophobicContact CG1-CE1 3.98Å; F666-L674 HydrophobicContact CD2-CD2 3.8Å; F666-L674 HydrophobicContact CE2-CD2 3.86Å; F666-V687 HydrophobicContact CE1-CG1 4.3Å; F666-V687 HydrophobicContact CZ-CG1 4.11Å; F666-I848 HydrophobicContact CB-CD1 3.76Å; F666-I848 HydrophobicContact CD1-CD1 3.86Å; F666-I848 HydrophobicContact CD2-CD1 3.54Å; F666-I848 HydrophobicContact CE1-CD1 4.33Å; F666-I848 HydrophobicContact CE2-CD1 4.05Å; F666-I848 HydrophobicContact CG-CD1 3.44Å; F666-I848 VanDerWaalsContact CG-CD1 3.44Å; F666-I848 HydrophobicContact CZ-CD1 4.41Å; F666-L855 HydrophobicContact CB-CD1 3.99Å; F666-L855 HydrophobicContact CD1-CD1 4.34Å; F666-Y858 HydrophobicContact CB-CE1 4.39Å
667T96.1Very high91.2Very high43 Ų4341 Ų4126%0.26422%0.22SC..EExtended strand (participates in β ladder)trans-134.6114.3-179-58.90000111.4E643 V644 V645 R846 Y858E643-T667 HydrophobicContact CG-CG2 4.34Å; V644-T667 CarbonylContact O-C 3.59Å; V644-T667 WeakPolarHBondContact O-CA 3.31Å; V645-T667 HydrophobicContact CG2-CG2 3.99Å; T667-R846 PolarHBondContact O-NH2 2.96Å; T667-Y858 PolarHBondContact O-OH 3.48Å
668L95.7Very high91.7Very high4 Ų440.3 Ų40.32%0.02122%0.218CC..EExtended strand (participates in β ladder)trans-81.7113.5166.3177.365.3000108.9E643 V644 E672 L674E643-L668 WeakPolarHBondContact CA-O 3.44Å; V644-L668 HydrophobicContact CB-CB 4.05Å; V644-L668 HydrophobicContact CB-CD2 4.35Å; V644-L668 HydrophobicContact CG2-CD2 4.04Å; V644-L668 PolarHBondContact N-O 3.23Å; V644-L668 PolarHBondContact O-N 3.08Å; L668-E672 HydrophobicContact CD1-CB 4.07Å; L668-E672 HydrophobicContact CD1-CG 4.39Å; L668-L674 HydrophobicContact CB-CD2 4.1Å; L668-L674 HydrophobicContact CD1-CB 3.49Å; L668-L674 VanDerWaalsContact CD1-CB 3.49Å; L668-L674 HydrophobicContact CD1-CD2 3.99Å; L668-L674 HydrophobicContact CD1-CG 4.42Å
669K94.3Very high91.4Very high110 Ų11040.4 Ų40.448%0.47821%0.205SC..  trans-76.5157.2179.5-65.1174.7-178.1179.30110.9G671 E672 S830K669-G671 PolarHBondContact O-N 3.04Å; K669-E672 HydrophobicContact CB-CB 4.03Å; K669-E672 WeakPolarHBondContact CB-OE2 3.41Å; K669-E672 PolarHBondContact N-OE2 2.92Å; K669-E672 WeakPolarHBondContact O-CB 3.34Å; K669-E672 PolarHBondContact O-N 3.05Å; K669-E672 VanDerWaalsContact O-N 3.14Å; K669-S830 PolarHBondContact O-OG 3.34Å
670P93.6Very high90.7Very high62 Ų6239.5 Ų39.540%0.40321%0.208SC..THydrogen-bonded Turntrans-53.5127173.9-2937.6000113.1H641 E643 E672 S830H641-P670 HydrophobicContact CB-CB 3.99Å; H641-P670 HydrophobicContact CB-CG 3.74Å; H641-P670 WeakPolarHBondContact O-CB 3.44Å; E643-P670 HydrophobicContact CB-CG 4.02Å; P670-E672 PolarHBondContact O-N 3.15Å; P670-S830 WeakPolarHBondContact CA-OG 3.38Å
671G90.2Very high89.7Confident33 Ų3340.1 Ų40.134%0.3423%0.228SC..THydrogen-bonded Turntrans70.89.817800000114.8K669 S830K669-G671 PolarHBondContact O-N 3.04Å; G671-S830 PolarHBondContact N-OG 3.12Å
672E92.9Very high89.2Confident13 Ų1340.4 Ų40.46%0.06123%0.231CC..  trans-85143.7-179.4-174.5-178.5-157.700112.1L668 K669 P670 S830 V831 D845 R846L668-E672 HydrophobicContact CD1-CB 4.07Å; L668-E672 HydrophobicContact CD1-CG 4.39Å; K669-E672 HydrophobicContact CB-CB 4.03Å; K669-E672 WeakPolarHBondContact CB-OE2 3.41Å; K669-E672 PolarHBondContact N-OE2 2.92Å; K669-E672 WeakPolarHBondContact O-CB 3.34Å; K669-E672 PolarHBondContact O-N 3.05Å; K669-E672 VanDerWaalsContact O-N 3.14Å; P670-E672 PolarHBondContact O-N 3.15Å; E672-S830 CarbonylContact O-C 3.54Å; E672-S830 WeakPolarHBondContact O-CA 3.31Å; E672-V831 PolarHBondContact O-N 3.06Å; E672-D845 WeakPolarHBondContact CA-OD2 3.24Å; E672-D845 HydrophobicContact CG-CB 3.68Å; E672-R846 IonicContact OE1-CZ 3.51Å; E672-R846 IonicContact OE1-NE 2.72Å; E672-R846 PolarHBondContact OE1-NE 3.34Å; E672-R846 IonicContact OE1-NH2 2.89Å; E672-R846 PolarHBondContact OE1-NH2 3.45Å; E672-R846 IonicContact OE2-CZ 2.79Å; E672-R846 IonicContact OE2-NE 2.81Å; E672-R846 IonicContact OE2-NH2 3.16Å; E672-R846 PolarHBondContact OE2-NH2 3.41Å
673K92.5Very high88.7Confident46 Ų4635 Ų3520%0.221%0.212CC..EExtended strand (participates in β ladder)trans-97.1111.8167.4-59.2-175.4-177-176.40110.6V831 C844 D845 R846K673-V831 CarbonylContact C-O 3.58Å; K673-V831 WeakPolarHBondContact CA-O 3.35Å; K673-V831 HydrophobicContact CG-CB 4.29Å; K673-V831 HydrophobicContact CG-CG2 4.44Å; K673-C844 CarbonylContact O-C 3.6Å; K673-C844 WeakPolarHBondContact O-CB 3.35Å; K673-D845 PolarHBondContact N-OD2 3.21Å; K673-D845 WeakPolarHBondContact O-CA 3.38Å; K673-D845 WeakPolarHBondContact O-CB 3.3Å; K673-D845 PolarHBondContact O-N 3.36Å; K673-R846 PolarHBondContact O-N 3.34Å
674L94.6Very high88.4Confident0 Ų030.3 Ų30.30%019%0.186CC..EExtended strand (participates in β ladder)trans-111.6121.5-179.1-176.760.7000110.4F666 L668 V831 L832 T833 R846 I848 Y858F666-L674 HydrophobicContact CD2-CD2 3.8Å; F666-L674 HydrophobicContact CE2-CD2 3.86Å; L668-L674 HydrophobicContact CB-CD2 4.1Å; L668-L674 HydrophobicContact CD1-CB 3.49Å; L668-L674 VanDerWaalsContact CD1-CB 3.49Å; L668-L674 HydrophobicContact CD1-CD2 3.99Å; L668-L674 HydrophobicContact CD1-CG 4.42Å; L674-V831 PolarHBondContact N-O 3.08Å; L674-L832 HydrophobicContact CB-CD1 4.32Å; L674-L832 HydrophobicContact CD2-CD1 4.08Å; L674-L832 HydrophobicContact CG-CD1 4.13Å; L674-L832 WeakPolarHBondContact O-CA 3.47Å; L674-T833 PolarHBondContact O-N 3.49Å; L674-R846 WeakPolarHBondContact CA-O 3.26Å; L674-R846 HydrophobicContact CD1-CB 3.87Å; L674-I848 HydrophobicContact CD1-CD1 4Å; L674-I848 HydrophobicContact CD1-CG1 4.01Å; L674-I848 HydrophobicContact CD2-CD1 3.76Å; L674-I848 HydrophobicContact CG-CD1 4.09Å; L674-Y858 HydrophobicContact CD1-CD2 4.46Å; L674-Y858 HydrophobicContact CD1-CE2 3.81Å
675G93.1Very high88Confident0 Ų032.4 Ų32.40%020%0.201CC..EExtended strand (participates in β ladder)trans-90.2142.8173.400000112.3T833 R846 V847 I848G675-T833 CarbonylContact C-O 3.54Å; G675-T833 WeakPolarHBondContact CA-O 3.28Å; G675-R846 PolarHBondContact N-O 2.88Å; G675-V847 CarbonylContact O-C 3.6Å; G675-V847 VanDerWaalsContact O-CA 3.32Å; G675-V847 WeakPolarHBondContact O-CA 3.3Å; G675-I848 PolarHBondContact O-N 2.87Å
676L92.5Very high87.7Confident1 Ų130.7 Ų30.71%0.00519%0.189CC..EExtended strand (participates in β ladder)trans-122.3114173.8-170.3101.3000109.1K684 V687 T833 I834 I848 L850L676-K684 HydrophobicContact CD2-CB 3.8Å; L676-K684 HydrophobicContact CD2-CG 4.05Å; L676-V687 HydrophobicContact CD1-CG2 4.39Å; L676-V687 HydrophobicContact CD2-CB 4.45Å; L676-V687 HydrophobicContact CD2-CG2 4.28Å; L676-T833 PolarHBondContact N-O 3.32Å; L676-I834 HydrophobicContact CB-CG1 4.2Å; L676-I834 HydrophobicContact CD2-CD1 3.59Å; L676-I834 HydrophobicContact CD2-CG1 3.82Å; L676-I834 HydrophobicContact CD2-CG2 4.48Å; L676-I848 HydrophobicContact CD1-CB 3.99Å; L676-I848 HydrophobicContact CD1-CD1 4.45Å; L676-I848 HydrophobicContact CD1-CG2 3.73Å; L676-L850 HydrophobicContact CD1-CD1 3.87Å; L676-L850 HydrophobicContact CD1-CG 4.13Å; L676-L850 HydrophobicContact CD2-CD1 3.91Å; L676-L850 HydrophobicContact CG-CD1 4.09Å; L676-L850 HydrophobicContact CG-CG 4.49Å
677V90Very high87.6Confident3 Ų330.2 Ų30.22%0.01819%0.187CC..EExtended strand (participates in β ladder)trans-122.5163.5-180-60.90000111.2L838 I841 V847 I848 V849 L850 F872 L875V677-L838 HydrophobicContact CG1-CD2 3.96Å; V677-I841 HydrophobicContact CG1-CD1 3.34Å; V677-I841 HydrophobicContact CG1-CG1 4.49Å; V677-I841 HydrophobicContact CG1-CG2 4.19Å; V677-V847 HydrophobicContact CG1-CG1 4.26Å; V677-V847 HydrophobicContact CG2-CG1 3.67Å; V677-I848 WeakPolarHBondContact CG2-O 3.45Å; V677-I848 PolarHBondContact N-O 3.29Å; V677-V849 HydrophobicContact CG2-CB 4.34Å; V677-V849 HydrophobicContact CG2-CG1 4.49Å; V677-V849 HydrophobicContact CG2-CG2 3.76Å; V677-V849 WeakPolarHBondContact O-CA 3.27Å; V677-L850 PolarHBondContact O-N 3.46Å; V677-F872 HydrophobicContact CG2-CD2 3.87Å; V677-F872 HydrophobicContact CG2-CE2 4.09Å; V677-L875 HydrophobicContact CG2-CD1 4.45Å
678G83.9Confident87.4Confident14 Ų1428.2 Ų28.214%0.14418%0.175CC..EExtended strand (participates in β ladder)trans158.3164.617900000110K684 L850G678-K684 PolarHBondContact O-NZ 3.28Å; G678-L850 WeakPolarHBondContact CA-O 3.4Å
679R74.7Confident87.3Confident98 Ų9828.4 Ų28.437%0.3718%0.176SC..SBendtrans-61.9163.3178.7-60.7-17374.7176.26.8111.5D302 G681 A682 K684 L875D302-R679 IonicContact OD2-CZ 3.9Å; D302-R679 IonicContact OD2-NE 2.72Å; D302-R679 IonicContact OD2-NH2 3.58Å; D302-R679 PolarHBondContact OD2-NH2 2.94Å; R679-G681 PolarHBondContact O-N 2.83Å; R679-A682 WeakPolarHBondContact O-CB 3.33Å; R679-A682 PolarHBondContact O-N 3.06Å; R679-A682 VanDerWaalsContact O-N 3.11Å; R679-K684 PolarHBondContact O-NZ 3.21Å; R679-K684 VanDerWaalsContact O-NZ 3.08Å; R679-L875 HydrophobicContact CG-CD2 4.31Å
680T70.9Confident87.3Confident61 Ų6123.2 Ų23.237%0.37415%0.153SC..THydrogen-bonded Turntrans-58.9130.4172.7-57.30000109.7
681G68.2Low87.3Confident68 Ų6820.3 Ų20.370%0.70113%0.134SC*.THydrogen-bonded Turntrans83.80.1-175.400000116R679 G683R679-G681 PolarHBondContact O-N 2.83Å; G681-G683 PolarHBondContact O-N 3.44Å
682A80.8Confident87.6Confident6 Ų618.8 Ų18.85%0.0512%0.118CC..SBendtrans-68-4.8179.600000115.3R679 L850 G853R679-A682 WeakPolarHBondContact O-CB 3.33Å; R679-A682 PolarHBondContact O-N 3.06Å; R679-A682 VanDerWaalsContact O-N 3.11Å; A682-L850 HydrophobicContact CB-CB 4.23Å; A682-L850 WeakPolarHBondContact CB-O 3.43Å; A682-G853 PolarHBondContact O-N 3.12Å
683G81.5Confident87.7Confident5 Ų518.8 Ų18.85%0.05212%0.118CC..SBendtrans100.313.2-178.200000115.2G681 S686 V687G681-G683 PolarHBondContact O-N 3.44Å; G683-S686 VanDerWaalsContact O-CB 3.25Å; G683-S686 WeakPolarHBondContact O-CB 3.33Å; G683-S686 PolarHBondContact O-N 3.36Å; G683-S686 VanDerWaalsContact O-N 3.12Å; G683-V687 PolarHBondContact O-N 3.34Å
684K85.9Confident87.6Confident12 Ų1216.8 Ų16.85%0.05211%0.109CC..Hα-helixtrans-53-61.2-178.2-61.5-169.2-62-89.30113.4L676 G678 R679 S686 V687 I834L676-K684 HydrophobicContact CD2-CB 3.8Å; L676-K684 HydrophobicContact CD2-CG 4.05Å; G678-K684 PolarHBondContact O-NZ 3.28Å; R679-K684 PolarHBondContact O-NZ 3.21Å; R679-K684 VanDerWaalsContact O-NZ 3.08Å; K684-S686 PolarHBondContact O-N 3.06Å; K684-V687 WeakPolarHBondContact O-CB 3.35Å; K684-V687 PolarHBondContact O-N 3.49Å; K684-I834 HydrophobicContact CB-CD1 4.31Å; K684-I834 HydrophobicContact CB-CG2 3.88Å; K684-I834 HydrophobicContact CD-CG2 4.03Å; K684-I834 VanDerWaalsContact O-CD1 3.27Å; K684-I834 WeakPolarHBondContact O-CD1 3.32Å
685S85.4Confident87.4Confident46 Ų4617.4 Ų17.432%0.32211%0.113SC..Hα-helixtrans-63.8-25.3178.4-43.20000112.5V687 I688 T689S685-V687 PolarHBondContact O-N 3.11Å; S685-I688 WeakPolarHBondContact O-CB 3.47Å; S685-I688 PolarHBondContact O-N 3.37Å; S685-I688 VanDerWaalsContact O-N 3.14Å; S685-T689 PolarHBondContact O-N 2.86Å; S685-T689 PolarHBondContact O-OG1 3.21Å
686S89.5Confident87.3Confident10 Ų1021.7 Ų21.77%0.0713%0.133CC..Hα-helixtrans-64.5-27.9174.4-57.20000112.5I660 G683 K684 I688 T689 A690I660-S686 WeakPolarHBondContact CG2-OG 3.26Å; G683-S686 VanDerWaalsContact O-CB 3.25Å; G683-S686 WeakPolarHBondContact O-CB 3.33Å; G683-S686 PolarHBondContact O-N 3.36Å; G683-S686 VanDerWaalsContact O-N 3.12Å; K684-S686 PolarHBondContact O-N 3.06Å; S686-I688 VanDerWaalsContact C-N 3.35Å; S686-T689 WeakPolarHBondContact O-CB 3.47Å; S686-T689 PolarHBondContact O-N 3.42Å; S686-A690 PolarHBondContact O-N 3.3Å
687V92.9Very high87.3Confident0 Ų022.9 Ų22.90%014%0.141CC..Hα-helixtrans-64.8-41.2172.8178.70000110.6F646 L661 F666 L676 G683 K684 S685 A690 L691 L850F646-V687 HydrophobicContact CE1-CG1 4.09Å; F646-V687 HydrophobicContact CZ-CG1 4.03Å; L661-V687 HydrophobicContact CD1-CG2 4.11Å; L661-V687 HydrophobicContact CD2-CG2 4.23Å; F666-V687 HydrophobicContact CE1-CG1 4.3Å; F666-V687 HydrophobicContact CZ-CG1 4.11Å; L676-V687 HydrophobicContact CD1-CG2 4.39Å; L676-V687 HydrophobicContact CD2-CB 4.45Å; L676-V687 HydrophobicContact CD2-CG2 4.28Å; G683-V687 PolarHBondContact O-N 3.34Å; K684-V687 WeakPolarHBondContact O-CB 3.35Å; K684-V687 PolarHBondContact O-N 3.49Å; S685-V687 PolarHBondContact O-N 3.11Å; V687-A690 PolarHBondContact O-N 3.13Å; V687-L691 WeakPolarHBondContact O-CB 3.45Å; V687-L691 PolarHBondContact O-N 3.28Å; V687-L850 HydrophobicContact CG2-CD1 3.83Å
688I93.2Very high87.5Confident1 Ų126.6 Ų26.61%0.00516%0.158CC..Hα-helixtrans-64.4-45.2174.1-60.2-178000110.1M28 S685 S686 A690 L691 F692 I722 V802 D804 I834M28-I688 HydrophobicContact CE-CG2 3.73Å; S685-I688 WeakPolarHBondContact O-CB 3.47Å; S685-I688 PolarHBondContact O-N 3.37Å; S685-I688 VanDerWaalsContact O-N 3.14Å; S686-I688 VanDerWaalsContact C-N 3.35Å; I688-A690 VanDerWaalsContact C-N 3.25Å; I688-A690 PolarHBondContact O-N 2.84Å; I688-L691 PolarHBondContact O-N 3.21Å; I688-L691 VanDerWaalsContact O-N 3.14Å; I688-F692 HydrophobicContact CG2-CD2 3.6Å; I688-F692 HydrophobicContact CG2-CE2 3.87Å; I688-F692 WeakPolarHBondContact O-CD2 3.43Å; I688-F692 PolarHBondContact O-N 2.79Å; I688-I722 HydrophobicContact CG2-CD1 3.84Å; I688-V802 HydrophobicContact CD1-CG1 3.74Å; I688-V802 HydrophobicContact CG1-CG1 3.92Å; I688-D804 HydrophobicContact CD1-CB 3.59Å; I688-D804 VanDerWaalsContact CD1-CG 3.47Å; I688-I834 HydrophobicContact CD1-CD1 3.41Å; I688-I834 VanDerWaalsContact CD1-CD1 3.41Å; I688-I834 HydrophobicContact CD1-CG1 4.07Å; I688-I834 HydrophobicContact CG1-CD1 3.53Å; I688-I834 HydrophobicContact CG1-CG1 4.43Å
689T92.3Very high87.9Confident8 Ų828.1 Ų28.15%0.04917%0.174CC..Hα-helixtrans-54.7-42.5176.2-59.30000111.8L651 Y653 S685 S686 R693 L694 V695L651-T689 HydrophobicContact CD2-CG2 4.16Å; Y653-T689 HydrophobicContact CE1-CG2 4.08Å; S685-T689 PolarHBondContact O-N 2.86Å; S685-T689 PolarHBondContact O-OG1 3.21Å; S686-T689 WeakPolarHBondContact O-CB 3.47Å; S686-T689 PolarHBondContact O-N 3.42Å; T689-R693 PolarHBondContact O-N 3.36Å; T689-L694 HydrophobicContact CG2-CB 3.9Å; T689-L694 PolarHBondContact O-N 3.02Å; T689-V695 HydrophobicContact CG2-CB 3.91Å; T689-V695 HydrophobicContact CG2-CG2 3.79Å
690A94.1Very high88.8Confident0 Ų027.6 Ų27.60%018%0.175CC..Hα-helixtrans-68.9-44.417600000112.1F646 V649 L651 S686 V687 I688 F692 R693 P697 I701F646-A690 HydrophobicContact CE1-CB 4.45Å; V649-A690 HydrophobicContact CG1-CB 4.31Å; L651-A690 HydrophobicContact CD1-CB 4.33Å; S686-A690 PolarHBondContact O-N 3.3Å; V687-A690 PolarHBondContact O-N 3.13Å; I688-A690 VanDerWaalsContact C-N 3.25Å; I688-A690 PolarHBondContact O-N 2.84Å; A690-F692 PolarHBondContact O-N 3.44Å; A690-R693 PolarHBondContact O-N 3.19Å; A690-R693 VanDerWaalsContact O-N 3.12Å; A690-P697 HydrophobicContact CB-CB 4.21Å; A690-P697 HydrophobicContact CB-CG 4.46Å; A690-I701 HydrophobicContact CB-CD1 4.18Å
691L95.3Very high90Very high2 Ų224.8 Ų24.81%0.0116%0.158CC..Hα-helixtrans-60.7-43.8-179.9-177.859.3000112.7V644 F646 V687 I688 R693 I701 I720 V802 L832V644-L691 HydrophobicContact CG1-CD1 3.87Å; F646-L691 HydrophobicContact CE2-CD1 4.17Å; F646-L691 HydrophobicContact CZ-CB 4.15Å; F646-L691 HydrophobicContact CZ-CD1 4.26Å; V687-L691 WeakPolarHBondContact O-CB 3.45Å; V687-L691 PolarHBondContact O-N 3.28Å; I688-L691 PolarHBondContact O-N 3.21Å; I688-L691 VanDerWaalsContact O-N 3.14Å; L691-R693 PolarHBondContact O-N 3.32Å; L691-I701 HydrophobicContact CD1-CG2 4.39Å; L691-I720 HydrophobicContact CD1-CD1 4.36Å; L691-I720 HydrophobicContact CG-CD1 4.24Å; L691-V802 HydrophobicContact CD2-CG2 3.75Å; L691-L832 HydrophobicContact CD2-CD2 4.24Å
692F95Very high91.4Very high0 Ų023.7 Ų23.70%013%0.133CC..THydrogen-bonded Turntrans-82.80.7178.5-79.3-90.4000113.6M28 I688 A690 L694 R717 I720 I722 V802M28-F692 HydrophobicContact CB-CD1 4.1Å; M28-F692 HydrophobicContact CB-CE1 4.17Å; M28-F692 HydrophobicContact CG-CD1 4.16Å; M28-F692 HydrophobicContact CG-CG 4.19Å; I688-F692 HydrophobicContact CG2-CD2 3.6Å; I688-F692 HydrophobicContact CG2-CE2 3.87Å; I688-F692 WeakPolarHBondContact O-CD2 3.43Å; I688-F692 PolarHBondContact O-N 2.79Å; A690-F692 PolarHBondContact O-N 3.44Å; F692-L694 HydrophobicContact CB-CD1 4.5Å; F692-L694 HydrophobicContact CB-CD2 4.32Å; F692-L694 HydrophobicContact CB-CG 3.93Å; F692-L694 PolarHBondContact O-N 2.81Å; F692-R717 HydrophobicContact CD1-CG 4.16Å; F692-R717 PolarHBondContact O-NE 2.92Å; F692-I720 HydrophobicContact CE1-CB 3.99Å; F692-I720 HydrophobicContact CE1-CG2 3.98Å; F692-I720 HydrophobicContact CE2-CG2 4.08Å; F692-I720 HydrophobicContact CZ-CB 3.97Å; F692-I720 HydrophobicContact CZ-CG2 3.43Å; F692-I720 VanDerWaalsContact CZ-CG2 3.43Å; F692-I722 HydrophobicContact CD2-CD1 4.5Å; F692-I722 HydrophobicContact CE2-CB 4.35Å; F692-I722 HydrophobicContact CE2-CD1 3.75Å; F692-I722 HydrophobicContact CZ-CB 3.81Å; F692-I722 HydrophobicContact CZ-CD1 4.03Å; F692-I722 HydrophobicContact CZ-CG1 4.5Å; F692-I722 HydrophobicContact CZ-CG2 4.16Å; F692-V802 HydrophobicContact CE2-CB 4.39Å; F692-V802 HydrophobicContact CE2-CG2 4.13Å
693R94.7Very high92.1Very high14 Ų1423.5 Ų23.55%0.05313%0.131CC..THydrogen-bonded Turntrans46.150-172.8-65.9178.359.7-150.6-6.6111.5T689 A690 L691 E696 T708 L711 L713 L716 R717T689-R693 PolarHBondContact O-N 3.36Å; A690-R693 PolarHBondContact O-N 3.19Å; A690-R693 VanDerWaalsContact O-N 3.12Å; L691-R693 PolarHBondContact O-N 3.32Å; R693-E696 IonicContact CZ-OE1 2.6Å; R693-E696 IonicContact CZ-OE2 3.91Å; R693-E696 IonicContact NE-OE1 3.13Å; R693-E696 PolarHBondContact NE-OE1 3.05Å; R693-E696 IonicContact NE-OE2 2.89Å; R693-E696 PolarHBondContact NE-OE2 3.4Å; R693-E696 VanDerWaalsContact NH2-CD 3.35Å; R693-E696 IonicContact NH2-OE1 2.67Å; R693-E696 PolarHBondContact NH2-OE1 3.45Å; R693-E696 IonicContact NH2-OE2 3.71Å; R693-E696 PolarHBondContact NH2-OE2 2.95Å; R693-T708 PolarHBondContact NH1-O 2.82Å; R693-L711 PolarHBondContact NH1-O 3.47Å; R693-L713 HydrophobicContact CB-CD2 3.87Å; R693-L716 HydrophobicContact CB-CD2 4.42Å; R693-L716 HydrophobicContact CG-CD2 4.04Å; R693-R717 PolarHBondContact O-NH2 3.05Å
694L92Very high92.6Very high3 Ų324.2 Ų24.22%0.01613%0.134CC..SBendtrans-77.6-31172.1-62.7-178.8000111R24 K27 M28 S496 I497 T689 F692R24-L694 HydrophobicContact CG-CD1 4.13Å; K27-L694 HydrophobicContact CB-CD2 3.79Å; K27-L694 HydrophobicContact CD-CD2 4.42Å; M28-L694 HydrophobicContact CE-CD1 3.54Å; M28-L694 HydrophobicContact CG-CD1 4.07Å; M28-L694 HydrophobicContact CG-CD2 4.46Å; S496-L694 PolarHBondContact OG-O 3.28Å; I497-L694 HydrophobicContact CG2-CB 4.26Å; T689-L694 HydrophobicContact CG2-CB 3.9Å; T689-L694 PolarHBondContact O-N 3.02Å; F692-L694 HydrophobicContact CB-CD1 4.5Å; F692-L694 HydrophobicContact CB-CD2 4.32Å; F692-L694 HydrophobicContact CB-CG 3.93Å; F692-L694 PolarHBondContact O-N 2.81Å
695V90.7Very high92.8Very high14 Ų1430 Ų309%0.08517%0.165CC..SBendtrans-129.1134.4165.61780000105.6I497 V498 L651 R652 Y653 T689 P697I497-V695 HydrophobicContact CG2-CG2 3.91Å; V498-V695 HydrophobicContact CG2-CG2 3.99Å; L651-V695 HydrophobicContact CD1-CB 4.08Å; L651-V695 HydrophobicContact CD1-CG1 3.97Å; R652-V695 WeakPolarHBondContact O-CG1 3.36Å; Y653-V695 HydrophobicContact CD1-CG2 3.72Å; Y653-V695 HydrophobicContact CE1-CG2 3.88Å; T689-V695 HydrophobicContact CG2-CB 3.91Å; T689-V695 HydrophobicContact CG2-CG2 3.79Å; V695-P697 VanDerWaalsContact O-CD 3.28Å; V695-P697 WeakPolarHBondContact O-CD 3.43Å
696E90.8Very high93.1Very high90 Ų9029.8 Ų29.842%0.42116%0.162SC..PPolyproline II helixtrans-67.9120.1-177.6-68.4-63.8168.800110.2A626 R693A626-E696 WeakPolarHBondContact CB-OE1 3.09Å; R693-E696 IonicContact CZ-OE1 2.6Å; R693-E696 IonicContact CZ-OE2 3.91Å; R693-E696 IonicContact NE-OE1 3.13Å; R693-E696 PolarHBondContact NE-OE1 3.05Å; R693-E696 IonicContact NE-OE2 2.89Å; R693-E696 PolarHBondContact NE-OE2 3.4Å; R693-E696 VanDerWaalsContact NH2-CD 3.35Å; R693-E696 IonicContact NH2-OE1 2.67Å; R693-E696 PolarHBondContact NH2-OE1 3.45Å; R693-E696 IonicContact NH2-OE2 3.71Å; R693-E696 PolarHBondContact NH2-OE2 2.95Å
697P92.7Very high93.3Very high26 Ų2630.7 Ų30.717%0.16917%0.166CC..PPolyproline II helixtrans-76.8150.1175.430.3-31.2000111.5V649 L651 A690 V695 I701V649-P697 HydrophobicContact CG1-CB 3.86Å; L651-P697 HydrophobicContact CD1-CB 4.09Å; A690-P697 HydrophobicContact CB-CB 4.21Å; A690-P697 HydrophobicContact CB-CG 4.46Å; V695-P697 VanDerWaalsContact O-CD 3.28Å; V695-P697 WeakPolarHBondContact O-CD 3.43Å; P697-I701 HydrophobicContact CG-CD1 4Å
698E92.8Very high93.3Very high80 Ų8030.8 Ų30.837%0.37417%0.167SC..EExtended strand (participates in β ladder)trans-82.8145.7160-64.3-178.7-166.900108.7V649 S650 R652 Y659V649-E698 CarbonylContact C-O 3.5Å; V649-E698 VanDerWaalsContact CA-O 3.27Å; V649-E698 WeakPolarHBondContact CA-O 3.21Å; S650-E698 PolarHBondContact N-O 3.47Å; S650-E698 PolarHBondContact O-N 3.47Å; R652-E698 IonicContact CZ-OE1 3.13Å; R652-E698 IonicContact NE-OE1 3.32Å; R652-E698 PolarHBondContact NE-OE1 3.02Å; R652-E698 IonicContact NH2-OE1 2.7Å; R652-E698 PolarHBondContact NH2-OE1 2.86Å; Y659-E698 PolarHBondContact OH-OE1 3.36Å; Y659-E698 VanDerWaalsContact OH-OE1 3.09Å; Y659-E698 PolarHBondContact OH-OE2 3.14Å
699G92.3Very high93.2Very high46 Ų4633.9 Ų33.947%0.47419%0.189SC..EExtended strand (participates in β ladder)trans96.6-162-169.200000112.4
700Q94.8Very high93.1Very high87 Ų8738 Ų3841%0.40721%0.214SC..EExtended strand (participates in β ladder)trans-135.5133.7-175.1-63.2175.7-1800111.4K647 Y702K647-Q700 PolarHBondContact N-O 3.1Å; K647-Q700 PolarHBondContact O-N 3.39Å; Q700-Y702 HydrophobicContact CB-CD2 4.29Å; Q700-Y702 HydrophobicContact CB-CE2 3.53Å; Q700-Y702 VanDerWaalsContact CD-OH 3.29Å; Q700-Y702 HydrophobicContact CG-CE2 4.45Å; Q700-Y702 PolarHBondContact OE1-OH 2.89Å
701I96.1Very high93Very high2 Ų238.5 Ų38.51%0.0122%0.217CC..EExtended strand (participates in β ladder)trans-117.4124.4172.4-58.7169.8000107.7V644 V645 F646 V649 A690 L691 P697 N707 T708V644-I701 HydrophobicContact CG1-CG2 4.27Å; V645-I701 CarbonylContact O-C 3.5Å; V645-I701 WeakPolarHBondContact O-CA 3.44Å; F646-I701 HydrophobicContact CD1-CD1 4.2Å; F646-I701 HydrophobicContact CD1-CG1 4.08Å; F646-I701 HydrophobicContact CD2-CG2 4.29Å; F646-I701 HydrophobicContact CE1-CD1 3.69Å; F646-I701 HydrophobicContact CE1-CG1 4.07Å; F646-I701 HydrophobicContact CE2-CG2 4.08Å; F646-I701 HydrophobicContact CG-CG1 4.33Å; F646-I701 HydrophobicContact CZ-CD1 3.89Å; F646-I701 HydrophobicContact CZ-CG1 4.32Å; F646-I701 HydrophobicContact CZ-CG2 4.41Å; V649-I701 HydrophobicContact CG1-CD1 4.48Å; V649-I701 HydrophobicContact CG2-CD1 4.32Å; V649-I701 HydrophobicContact CG2-CG1 3.66Å; A690-I701 HydrophobicContact CB-CD1 4.18Å; L691-I701 HydrophobicContact CD1-CG2 4.39Å; P697-I701 HydrophobicContact CG-CD1 4Å; I701-N707 PolarHBondContact O-OD1 3.35Å; I701-T708 HydrophobicContact CB-CG2 4.37Å; I701-T708 WeakPolarHBondContact CB-OG1 3.17Å; I701-T708 HydrophobicContact CG2-CG2 4.03Å; I701-T708 WeakPolarHBondContact O-CB 3.3Å; I701-T708 WeakPolarHBondContact O-CG2 3.35Å; I701-T708 PolarHBondContact O-N 2.81Å; I701-T708 PolarHBondContact O-OG1 3.27Å
702Y96.3Very high92.9Very high46 Ų4638.5 Ų38.518%0.1822%0.217CC..EExtended strand (participates in β ladder)trans-110.1141.5177.7-62-97.5000110.5V644 V645 K647 Q700 V706 N707V644-Y702 CarbonylContact C-O 3.53Å; V644-Y702 WeakPolarHBondContact CA-O 3.27Å; V645-Y702 PolarHBondContact N-O 3.43Å; V645-Y702 PolarHBondContact O-N 3.31Å; K647-Y702 HydrophobicContact CD-CD2 4.23Å; K647-Y702 HydrophobicContact CD-CE2 3.86Å; K647-Y702 HydrophobicContact CG-CD2 4.47Å; K647-Y702 HydrophobicContact CG-CE2 4.41Å; Q700-Y702 HydrophobicContact CB-CD2 4.29Å; Q700-Y702 HydrophobicContact CB-CE2 3.53Å; Q700-Y702 VanDerWaalsContact CD-OH 3.29Å; Q700-Y702 HydrophobicContact CG-CE2 4.45Å; Q700-Y702 PolarHBondContact OE1-OH 2.89Å; Y702-V706 CarbonylContact C-O 3.53Å; Y702-V706 VanDerWaalsContact CA-O 3.29Å; Y702-V706 WeakPolarHBondContact CA-O 3.35Å; Y702-N707 HydrophobicContact CD1-CB 4.1Å; Y702-N707 HydrophobicContact CE1-CB 3.88Å
703I95.2Very high92.8Very high1 Ų138.5 Ų38.51%0.00522%0.217CC..EExtended strand (participates in β ladder)trans-124.8119.7168.7-63.4177.4000108.3W638 P639 E643 V644 N705 V706 T708 L716 I720 I800W638-I703 HydrophobicContact CH2-CB 4.29Å; W638-I703 HydrophobicContact CH2-CG2 4.2Å; W638-I703 HydrophobicContact CZ2-CB 3.67Å; W638-I703 HydrophobicContact CZ2-CG2 3.65Å; W638-I703 PolarHBondContact NE1-O 3.25Å; W638-I703 VanDerWaalsContact NE1-O 3.09Å; P639-I703 HydrophobicContact CB-CG2 3.85Å; P639-I703 HydrophobicContact CG-CG2 4.36Å; E643-I703 CarbonylContact O-C 3.46Å; E643-I703 VanDerWaalsContact O-CA 3.24Å; E643-I703 WeakPolarHBondContact O-CA 3.49Å; V644-I703 HydrophobicContact CG1-CG1 4.24Å; V644-I703 HydrophobicContact CG2-CG1 4.21Å; I703-N705 VanDerWaalsContact C-N 3.29Å; I703-N705 PolarHBondContact O-N 3.49Å; I703-V706 PolarHBondContact N-O 3.39Å; I703-V706 WeakPolarHBondContact O-CB 3.43Å; I703-V706 PolarHBondContact O-N 3.44Å; I703-T708 HydrophobicContact CB-CG2 4.41Å; I703-T708 HydrophobicContact CD1-CG2 3.77Å; I703-T708 HydrophobicContact CG1-CG2 3.76Å; I703-L716 HydrophobicContact CD1-CD1 3.61Å; I703-I720 HydrophobicContact CD1-CD1 3.91Å; I703-I800 HydrophobicContact CD1-CD1 4.23Å; I703-I800 HydrophobicContact CG2-CD1 3.69Å
704D93Very high92.7Very high21 Ų2139.2 Ų39.211%0.11222%0.221CC..THydrogen-bonded Turntrans44.851.1-171.4-73-1.8000112.5P639 S640 H641 G642 E643 V706P639-D704 WeakPolarHBondContact CA-OD2 3.15Å; P639-D704 WeakPolarHBondContact CB-OD2 3.13Å; S640-D704 PolarHBondContact N-OD2 3.18Å; S640-D704 PolarHBondContact OG-OD2 3.4Å; H641-D704 PolarHBondContact N-OD2 3.2Å; G642-D704 PolarHBondContact N-OD1 3.08Å; G642-D704 PolarHBondContact N-OD2 3.27Å; E643-D704 PolarHBondContact N-OD1 3.44Å; E643-D704 PolarHBondContact O-N 2.96Å; D704-V706 PolarHBondContact O-N 3.42Å; D704-V706 VanDerWaalsContact O-N 3.1Å
705N90.2Very high92.7Very high132 Ų13240.9 Ų40.971%0.70623%0.228SC*.THydrogen-bonded Turntrans64.12-176.5-60.6-57000117I703I703-N705 VanDerWaalsContact C-N 3.29Å; I703-N705 PolarHBondContact O-N 3.49Å
706V92.6Very high92.8Very high43 Ų4340.2 Ų40.226%0.26122%0.224SC..EExtended strand (participates in β ladder)trans-92.3126.8174.2-177.10000109.6W638 Y702 I703 D704 T708 L711W638-V706 HydrophobicContact CZ2-CB 4.14Å; W638-V706 HydrophobicContact CZ2-CG1 4.49Å; Y702-V706 CarbonylContact C-O 3.53Å; Y702-V706 VanDerWaalsContact CA-O 3.29Å; Y702-V706 WeakPolarHBondContact CA-O 3.35Å; I703-V706 PolarHBondContact N-O 3.39Å; I703-V706 WeakPolarHBondContact O-CB 3.43Å; I703-V706 PolarHBondContact O-N 3.44Å; D704-V706 PolarHBondContact O-N 3.42Å; D704-V706 VanDerWaalsContact O-N 3.1Å; V706-T708 PolarHBondContact O-N 3.03Å; V706-L711 HydrophobicContact CG1-CD1 4.05Å; V706-L711 HydrophobicContact CG1-CD2 3.94Å; V706-L711 HydrophobicContact CG1-CG 4.08Å
707N93.3Very high93Very high28 Ų2835.9 Ų35.915%0.1520%0.204CC..EExtended strand (participates in β ladder)trans-68.9123.3176.2-171.4-15.9000110I701 Y702 S709 T710I701-N707 PolarHBondContact O-OD1 3.35Å; Y702-N707 HydrophobicContact CD1-CB 4.1Å; Y702-N707 HydrophobicContact CE1-CB 3.88Å; N707-S709 VanDerWaalsContact CG-OG 3.3Å; N707-S709 PolarHBondContact ND2-OG 3.4Å; N707-S709 PolarHBondContact O-N 3.45Å; N707-S709 PolarHBondContact OD1-N 2.95Å; N707-S709 PolarHBondContact OD1-OG 3.04Å; N707-S709 VanDerWaalsContact OD1-OG 3.06Å; N707-T710 PolarHBondContact O-N 3.28Å; N707-T710 PolarHBondContact O-OG1 3.16Å
708T92.7Very high93Very high3 Ų338.6 Ų38.62%0.01821%0.213CC..G310 helixtrans-63.8-23.1-179.657.40000113.1R693 I701 I703 V706 T710 L711 L716R693-T708 PolarHBondContact NH1-O 2.82Å; I701-T708 HydrophobicContact CB-CG2 4.37Å; I701-T708 WeakPolarHBondContact CB-OG1 3.17Å; I701-T708 HydrophobicContact CG2-CG2 4.03Å; I701-T708 WeakPolarHBondContact O-CB 3.3Å; I701-T708 WeakPolarHBondContact O-CG2 3.35Å; I701-T708 PolarHBondContact O-N 2.81Å; I701-T708 PolarHBondContact O-OG1 3.27Å; I703-T708 HydrophobicContact CB-CG2 4.41Å; I703-T708 HydrophobicContact CD1-CG2 3.77Å; I703-T708 HydrophobicContact CG1-CG2 3.76Å; V706-T708 PolarHBondContact O-N 3.03Å; T708-T710 VanDerWaalsContact C-N 3.31Å; T708-T710 PolarHBondContact O-N 3.02Å; T708-L711 PolarHBondContact O-N 3.21Å; T708-L716 HydrophobicContact CG2-CD1 3.88Å; T708-L716 HydrophobicContact CG2-CD2 4.48Å
709S90.9Very high93Very high66 Ų6637.9 Ų37.946%0.46221%0.209SC..G310 helixtrans-70.3-24.1179.670.40000113.9N707N707-S709 VanDerWaalsContact CG-OG 3.3Å; N707-S709 PolarHBondContact ND2-OG 3.4Å; N707-S709 PolarHBondContact O-N 3.45Å; N707-S709 PolarHBondContact OD1-N 2.95Å; N707-S709 PolarHBondContact OD1-OG 3.04Å; N707-S709 VanDerWaalsContact OD1-OG 3.06Å
710T90.6Very high93.1Very high95 Ų9535.8 Ų35.858%0.58319%0.187SC*.G310 helixtrans-85.7-12.9178.457.30000113.1S630 N707 T708S630-T710 WeakPolarHBondContact CB-O 3.41Å; N707-T710 PolarHBondContact O-N 3.28Å; N707-T710 PolarHBondContact O-OG1 3.16Å; T708-T710 VanDerWaalsContact C-N 3.31Å; T708-T710 PolarHBondContact O-N 3.02Å
711L91.4Very high93.1Very high10 Ų1031.7 Ų31.75%0.05217%0.167CC..SBendtrans-84.7151.9-178.5-63177.8000112.1P634 W638 R693 V706 T708P634-L711 VanDerWaalsContact CD-CD2 3.5Å; P634-L711 HydrophobicContact CG-CD2 3.79Å; W638-L711 HydrophobicContact CH2-CD1 3.15Å; W638-L711 HydrophobicContact CZ2-CD1 3.55Å; W638-L711 HydrophobicContact CZ3-CD1 3.81Å; R693-L711 PolarHBondContact NH1-O 3.47Å; V706-L711 HydrophobicContact CG1-CD1 4.05Å; V706-L711 HydrophobicContact CG1-CD2 3.94Å; V706-L711 HydrophobicContact CG1-CG 4.08Å; T708-L711 PolarHBondContact O-N 3.21Å
712G92.8Very high93Very high1 Ų131.6 Ų31.61%0.0117%0.167CC..  trans-68.6145.3166.900000110.5E627 L628 H714 E715 L716E627-G712 WeakPolarHBondContact O-CA 3.38Å; L628-G712 CarbonylContact O-C 3.58Å; L628-G712 VanDerWaalsContact O-C 3.26Å; L628-G712 WeakPolarHBondContact O-CA 3.18Å; G712-H714 VanDerWaalsContact C-N 3.3Å; G712-H714 PolarHBondContact O-N 3.49Å; G712-E715 PolarHBondContact N-OE2 3.18Å; G712-E715 WeakPolarHBondContact O-CB 3.25Å; G712-E715 PolarHBondContact O-N 3.2Å; G712-E715 VanDerWaalsContact O-N 3.13Å; G712-L716 PolarHBondContact O-N 2.85Å
713L93.4Very high92.8Very high0 Ų029.5 Ų29.50%016%0.159CC..Hα-helixtrans-61.3-36.6-177.2-64.8175.8000112.9E625 A626 E627 L628 R693 R717E625-L713 HydrophobicContact CB-CD1 3.73Å; A626-L713 HydrophobicContact CB-CD1 3.99Å; A626-L713 HydrophobicContact CB-CD2 4.24Å; A626-L713 HydrophobicContact CB-CG 4.05Å; A626-L713 WeakPolarHBondContact O-CD1 3.41Å; E627-L713 PolarHBondContact O-N 3.41Å; L628-L713 HydrophobicContact CD2-CB 4.44Å; L628-L713 PolarHBondContact O-N 2.95Å; R693-L713 HydrophobicContact CB-CD2 3.87Å; L713-R717 WeakPolarHBondContact O-CB 3.45Å; L713-R717 VanDerWaalsContact O-CD 3.3Å; L713-R717 WeakPolarHBondContact O-CD 3.34Å; L713-R717 WeakPolarHBondContact O-CG 3.28Å; L713-R717 PolarHBondContact O-N 2.95Å
714H92.4Very high92.5Very high30 Ų3029.8 Ų29.814%0.13916%0.161CC..Hα-helixtrans-71-35.4176.3-77.9-175.6000112E32 L628 G712 L716 K718E32-H714 IonicContact OE2-NE2 2.98Å; E32-H714 PolarHBondContact OE2-NE2 3.38Å; L628-H714 WeakPolarHBondContact CD2-NE2 3.43Å; L628-H714 WeakPolarHBondContact O-CB 3.47Å; L628-H714 PolarHBondContact O-N 2.95Å; G712-H714 VanDerWaalsContact C-N 3.3Å; G712-H714 PolarHBondContact O-N 3.49Å; H714-L716 VanDerWaalsContact C-N 3.32Å; H714-L716 PolarHBondContact O-N 2.95Å; H714-K718 WeakPolarHBondContact O-CB 3.32Å; H714-K718 WeakPolarHBondContact O-CG 3.49Å; H714-K718 PolarHBondContact O-N 2.7Å
715E91.5Very high91.9Very high37 Ų3732.3 Ų32.317%0.17317%0.172CC..Hα-helixtrans-62.6-42176.3-66.7158.2-163.800110.8T629 S630 G712 K719T629-E715 WeakPolarHBondContact CA-OE1 3.4Å; S630-E715 WeakPolarHBondContact CB-OE2 3.42Å; S630-E715 PolarHBondContact N-OE1 3.37Å; S630-E715 PolarHBondContact N-OE2 3.03Å; S630-E715 PolarHBondContact OG-OE1 2.74Å; S630-E715 PolarHBondContact OG-OE2 3.46Å; G712-E715 PolarHBondContact N-OE2 3.18Å; G712-E715 WeakPolarHBondContact O-CB 3.25Å; G712-E715 PolarHBondContact O-N 3.2Å; G712-E715 VanDerWaalsContact O-N 3.13Å; E715-K719 VanDerWaalsContact O-CG 3.3Å; E715-K719 WeakPolarHBondContact O-CG 3.43Å
716L94Very high91.2Very high0 Ų030.8 Ų30.80%016%0.164CC..Hα-helixtrans-69.5-58.8176177.663.4000112W638 R693 I703 T708 G712 H714 K718 K719 I720W638-L716 HydrophobicContact CH2-CD1 4.24Å; R693-L716 HydrophobicContact CB-CD2 4.42Å; R693-L716 HydrophobicContact CG-CD2 4.04Å; I703-L716 HydrophobicContact CD1-CD1 3.61Å; T708-L716 HydrophobicContact CG2-CD1 3.88Å; T708-L716 HydrophobicContact CG2-CD2 4.48Å; G712-L716 PolarHBondContact O-N 2.85Å; H714-L716 VanDerWaalsContact C-N 3.32Å; H714-L716 PolarHBondContact O-N 2.95Å; L716-K718 VanDerWaalsContact C-N 3.29Å; L716-K718 PolarHBondContact O-N 3.48Å; L716-K719 PolarHBondContact O-N 3.02Å; L716-I720 HydrophobicContact CD1-CD1 3.9Å; L716-I720 HydrophobicContact CG-CD1 4.34Å
717R95.2Very high90.9Very high0 Ų029.2 Ų29.20%015%0.154CC..Hα-helixtrans-65.8-31.5-170.9-65.4164.4174.6176.97.9111.7K27 A30 E32 E625 F692 R693 L713 K719 I720 R796K27-R717 VanDerWaalsContact O-CD 3.3Å; K27-R717 WeakPolarHBondContact O-CD 3.46Å; A30-R717 HydrophobicContact CB-CB 4.08Å; E32-R717 IonicContact OE1-NH1 3.59Å; E32-R717 PolarHBondContact OE1-NH1 3.24Å; E625-R717 IonicContact OE2-CZ 2.72Å; E625-R717 IonicContact OE2-NH1 2.75Å; E625-R717 PolarHBondContact OE2-NH1 3.05Å; E625-R717 VanDerWaalsContact OE2-NH1 3.14Å; E625-R717 IonicContact OE2-NH2 3.03Å; E625-R717 PolarHBondContact OE2-NH2 2.89Å; F692-R717 HydrophobicContact CD1-CG 4.16Å; F692-R717 PolarHBondContact O-NE 2.92Å; R693-R717 PolarHBondContact O-NH2 3.05Å; L713-R717 WeakPolarHBondContact O-CB 3.45Å; L713-R717 VanDerWaalsContact O-CD 3.3Å; L713-R717 WeakPolarHBondContact O-CD 3.34Å; L713-R717 WeakPolarHBondContact O-CG 3.28Å; L713-R717 PolarHBondContact O-N 2.95Å; R717-K719 VanDerWaalsContact C-N 3.25Å; R717-K719 PolarHBondContact O-N 3.41Å; R717-I720 PolarHBondContact O-N 3.04Å; R717-R796 PolarHBondContact O-NH2 3.42Å
718K92Very high90.5Very high82 Ų8229.7 Ų29.736%0.35716%0.157SC..Hα-helixtrans-65.7-24174.3-76.3-173.8173.2-154.80113.6A30 H714 L716 R796 N798A30-K718 HydrophobicContact CB-CG 3.89Å; H714-K718 WeakPolarHBondContact O-CB 3.32Å; H714-K718 WeakPolarHBondContact O-CG 3.49Å; H714-K718 PolarHBondContact O-N 2.7Å; L716-K718 VanDerWaalsContact C-N 3.29Å; L716-K718 PolarHBondContact O-N 3.48Å; K718-R796 PolarHBondContact O-NH2 3.17Å; K718-N798 PolarHBondContact O-ND2 3.12Å; K718-N798 VanDerWaalsContact O-ND2 3.15Å; K718-N798 PolarHBondContact O-OD1 3.4Å
719K92.9Very high90.4Very high66 Ų6629.6 Ų29.629%0.28716%0.156SC..THydrogen-bonded Turntrans-97.40.3-177.1-64.4-63.9-171.6164.30114.9E636 W638 P639 E715 L716 R717 N798E636-K719 PolarHBondContact O-NZ 2.92Å; W638-K719 HydrophobicContact CE3-CG 4.23Å; W638-K719 HydrophobicContact CZ3-CB 4.23Å; W638-K719 HydrophobicContact CZ3-CG 4.16Å; W638-K719 VanDerWaalsContact O-CD 3.3Å; W638-K719 WeakPolarHBondContact O-CD 3.49Å; W638-K719 WeakPolarHBondContact O-CE 3.18Å; W638-K719 PolarHBondContact O-NZ 2.96Å; P639-K719 HydrophobicContact CG-CB 4.43Å; E715-K719 VanDerWaalsContact O-CG 3.3Å; E715-K719 WeakPolarHBondContact O-CG 3.43Å; L716-K719 PolarHBondContact O-N 3.02Å; R717-K719 VanDerWaalsContact C-N 3.25Å; R717-K719 PolarHBondContact O-N 3.41Å; K719-N798 VanDerWaalsContact C-CG 3.41Å; K719-N798 WeakPolarHBondContact CA-OD1 3.4Å; K719-N798 WeakPolarHBondContact O-CB 3.48Å; K719-N798 VanDerWaalsContact O-CG 3.27Å; K719-N798 PolarHBondContact O-OD1 3.36Å
720I94.3Very high90.3Very high1 Ų126.8 Ų26.81%0.00514%0.135CC..EExtended strand (participates in β ladder)trans-117125.7174.9-53.3174.4000108.9L691 F692 I703 L716 R717 R796 I800 V802L691-I720 HydrophobicContact CD1-CD1 4.36Å; L691-I720 HydrophobicContact CG-CD1 4.24Å; F692-I720 HydrophobicContact CE1-CB 3.99Å; F692-I720 HydrophobicContact CE1-CG2 3.98Å; F692-I720 HydrophobicContact CE2-CG2 4.08Å; F692-I720 HydrophobicContact CZ-CB 3.97Å; F692-I720 HydrophobicContact CZ-CG2 3.43Å; F692-I720 VanDerWaalsContact CZ-CG2 3.43Å; I703-I720 HydrophobicContact CD1-CD1 3.91Å; L716-I720 HydrophobicContact CD1-CD1 3.9Å; L716-I720 HydrophobicContact CG-CD1 4.34Å; R717-I720 PolarHBondContact O-N 3.04Å; I720-R796 VanDerWaalsContact O-CZ 3.32Å; I720-R796 PolarHBondContact O-NH1 2.96Å; I720-R796 PolarHBondContact O-NH2 3.23Å; I720-R796 VanDerWaalsContact O-NH2 3.09Å; I720-I800 HydrophobicContact CG2-CB 4.43Å; I720-I800 HydrophobicContact CG2-CG2 4.05Å; I720-V802 HydrophobicContact CG2-CG2 3.87Å
721S94.6Very high90.1Very high1 Ų125.3 Ų25.31%0.00712%0.124CC..EExtended strand (participates in β ladder)trans-90.5141.3172.4-73.50000110.4A793 N798 I800 L801 V802S721-A793 PolarHBondContact OG-O 3.24Å; S721-N798 PolarHBondContact N-ND2 3Å; S721-N798 PolarHBondContact OG-ND2 3.25Å; S721-N798 VanDerWaalsContact OG-ND2 3.1Å; S721-I800 PolarHBondContact N-O 2.89Å; S721-L801 CarbonylContact O-C 3.57Å; S721-L801 WeakPolarHBondContact O-CA 3.38Å; S721-V802 PolarHBondContact O-N 3.32Å
722I93.9Very high89.8Confident1 Ų125.8 Ų25.81%0.00513%0.131CC..EExtended strand (participates in β ladder)trans-133.2143.1177.7-175.2157.3000111.4M28 Y29 I688 F692 V802M28-I722 HydrophobicContact CB-CG2 4.02Å; M28-I722 HydrophobicContact CE-CD1 4.18Å; M28-I722 HydrophobicContact SD-CD1 3.68Å; Y29-I722 HydrophobicContact CD1-CG2 4.31Å; Y29-I722 HydrophobicContact CE1-CG2 3.89Å; Y29-I722 PolarHBondContact OH-O 2.77Å; Y29-I722 VanDerWaalsContact OH-O 3.06Å; I688-I722 HydrophobicContact CG2-CD1 3.84Å; F692-I722 HydrophobicContact CD2-CD1 4.5Å; F692-I722 HydrophobicContact CE2-CB 4.35Å; F692-I722 HydrophobicContact CE2-CD1 3.75Å; F692-I722 HydrophobicContact CZ-CB 3.81Å; F692-I722 HydrophobicContact CZ-CD1 4.03Å; F692-I722 HydrophobicContact CZ-CG1 4.5Å; F692-I722 HydrophobicContact CZ-CG2 4.16Å; I722-V802 CarbonylContact C-O 3.44Å; I722-V802 VanDerWaalsContact CA-O 3.3Å; I722-V802 WeakPolarHBondContact CA-O 3.27Å; I722-V802 HydrophobicContact CB-CB 4.48Å; I722-V802 HydrophobicContact CD1-CG1 4.32Å; I722-V802 HydrophobicContact CG1-CB 4.33Å
723I92.3Very high89.7Confident2 Ų227.5 Ų27.51%0.0114%0.142CC..EExtended strand (participates in β ladder)trans-113.2105.5164.7-53.1-171.3000107C789 L790 A793 L801 V802 L803 D804 A806I723-C789 HydrophobicContact CG2-CB 4.31Å; I723-L790 HydrophobicContact CD1-CB 4.26Å; I723-L790 HydrophobicContact CD1-CD1 3.4Å; I723-L790 VanDerWaalsContact CD1-CD1 3.4Å; I723-L790 HydrophobicContact CD1-CG 4.43Å; I723-A793 HydrophobicContact CG1-CB 4.36Å; I723-L801 HydrophobicContact CG1-CD1 4.28Å; I723-V802 PolarHBondContact N-O 3.27Å; I723-L803 HydrophobicContact CB-CD2 3.86Å; I723-L803 HydrophobicContact CD1-CD2 3.48Å; I723-L803 VanDerWaalsContact CD1-CD2 3.48Å; I723-L803 HydrophobicContact CG1-CD2 3.73Å; I723-D804 PolarHBondContact O-N 3.25Å; I723-A806 HydrophobicContact CB-CB 4.34Å; I723-A806 HydrophobicContact CG2-CB 3.76Å
724P88.1Confident89.7Confident7 Ų727.5 Ų27.55%0.04514%0.142CC..  trans-74.5163.7-175.331.6-35.7000112.2V25 Y29 Q786 D804V25-P724 HydrophobicContact CG2-CB 4.31Å; V25-P724 HydrophobicContact CG2-CG 4.49Å; Y29-P724 WeakPolarHBondContact OH-CD 3.16Å; P724-Q786 PolarHBondContact O-NE2 3.15Å; P724-D804 CarbonylContact C-O 3.59Å
725Q80.5Confident89.8Confident73 Ų7331.2 Ų31.234%0.34115%0.154SC..SBendtrans-60.9-46.3173.2-177.2175.721.200111.8P727 D804 E805Q725-P727 WeakPolarHBondContact O-CD 3.24Å; Q725-D804 WeakPolarHBondContact CA-O 3.4Å; Q725-D804 PolarHBondContact N-O 3.36Å; Q725-E805 HydrophobicContact CG-CB 4.25Å; Q725-E805 PolarHBondContact NE2-OE2 2.96Å
726D76.6Confident89.7Confident100 Ų10034.9 Ų34.954%0.53517%0.171SC..SBendtrans-102.7104.9177-65.2-38.5000110.2I728D726-I728 PolarHBondContact O-N 3.13Å
727P85.4Confident89.7Confident10 Ų1035 Ų357%0.06517%0.172CC..  trans-75.698.2-179.931.5-37.1000111Q725 R785 Q786 C789Q725-P727 WeakPolarHBondContact O-CD 3.24Å; P727-R785 HydrophobicContact CB-CB 3.84Å; P727-R785 HydrophobicContact CG-CB 3.72Å; P727-Q786 VanDerWaalsContact CB-OE1 3.28Å; P727-C789 VanDerWaalsContact CB-SG 3.57Å
728I85.9Confident89.6Confident39 Ų3935.3 Ų35.320%0.217%0.174CC..  trans-88.1127.4-179.8-56.8173.7000110.8A22 V25 D726 F730 R792A22-I728 HydrophobicContact CB-CD1 3.71Å; A22-I728 HydrophobicContact CB-CG2 4.04Å; V25-I728 HydrophobicContact CG2-CD1 4.03Å; D726-I728 PolarHBondContact O-N 3.13Å; I728-F730 HydrophobicContact CG2-CE1 4.27Å; I728-F730 HydrophobicContact CG2-CZ 4.2Å; I728-R792 PolarHBondContact O-NH1 3.42Å; I728-R792 PolarHBondContact O-NH2 3.38Å
729L89.6Confident89.7Confident0 Ų032 Ų320%016%0.16CC..  trans-107.9144.1163.5-54.5-178.5000109T773 G776 F780 R785 I788L729-T773 HydrophobicContact CD1-CG2 4.49Å; L729-G776 CarbonylContact O-C 3.58Å; L729-G776 VanDerWaalsContact O-CA 3.23Å; L729-G776 WeakPolarHBondContact O-CA 3.39Å; L729-G776 PolarHBondContact O-N 3.02Å; L729-F780 HydrophobicContact CD1-CD2 3.74Å; L729-F780 HydrophobicContact CD1-CE2 4.29Å; L729-F780 HydrophobicContact CD1-CG 4.31Å; L729-R785 HydrophobicContact CD1-CG 3.96Å; L729-R785 HydrophobicContact CG-CG 4.27Å; L729-I788 HydrophobicContact CD1-CD1 3.79Å; L729-I788 HydrophobicContact CD2-CB 4.32Å; L729-I788 HydrophobicContact CD2-CG2 3.62Å
730F89Confident89.5Confident7 Ų730.5 Ų30.53%0.03116%0.157CC..  trans-99.1154.4-177.3-59.8-84.9000111.1E18 A22 I26 W31 F35 I728 G732 N737 T773E18-F730 HydrophobicContact CG-CD1 4.02Å; E18-F730 VanDerWaalsContact OE1-CA 3.26Å; E18-F730 WeakPolarHBondContact OE1-CA 3.32Å; A22-F730 HydrophobicContact CB-CE1 3.54Å; A22-F730 HydrophobicContact CB-CZ 3.79Å; I26-F730 HydrophobicContact CD1-CE1 3.82Å; I26-F730 HydrophobicContact CD1-CZ 4Å; I26-F730 HydrophobicContact CG1-CE1 3.99Å; I26-F730 HydrophobicContact CG1-CZ 3.63Å; W31-F730 HydrophobicContact CE3-CE2 4.05Å; W31-F730 HydrophobicContact CZ3-CD2 4.34Å; W31-F730 AromaticContact CZ3-CE2 3.88Å; W31-F730 HydrophobicContact CZ3-CE2 3.88Å; F35-F730 HydrophobicContact CE1-CB 4.14Å; F35-F730 AromaticContact CE1-CD1 3.65Å; F35-F730 HydrophobicContact CE1-CD1 3.65Å; F35-F730 HydrophobicContact CE1-CD2 4.28Å; F35-F730 HydrophobicContact CE1-CE1 4.1Å; F35-F730 AromaticContact CE1-CG 3.75Å; F35-F730 HydrophobicContact CE1-CG 3.75Å; F35-F730 HydrophobicContact CE2-CD2 4.38Å; F35-F730 HydrophobicContact CE2-CE1 4.3Å; F35-F730 HydrophobicContact CE2-CE2 4.13Å; F35-F730 HydrophobicContact CE2-CZ 4.09Å; F35-F730 HydrophobicContact CZ-CB 4.18Å; F35-F730 AromaticContact CZ-CD1 3.57Å; F35-F730 HydrophobicContact CZ-CD1 3.57Å; F35-F730 AromaticContact CZ-CD2 3.51Å; F35-F730 HydrophobicContact CZ-CD2 3.51Å; F35-F730 AromaticContact CZ-CE1 3.73Å; F35-F730 HydrophobicContact CZ-CE1 3.73Å; F35-F730 AromaticContact CZ-CE2 3.68Å; F35-F730 HydrophobicContact CZ-CE2 3.68Å; F35-F730 AromaticContact CZ-CG 3.45Å; F35-F730 HydrophobicContact CZ-CG 3.45Å; F35-F730 VanDerWaalsContact CZ-CG 3.45Å; F35-F730 AromaticContact CZ-CZ 3.8Å; F35-F730 HydrophobicContact CZ-CZ 3.8Å; I728-F730 HydrophobicContact CG2-CE1 4.27Å; I728-F730 HydrophobicContact CG2-CZ 4.2Å; F730-G732 PolarHBondContact O-N 2.96Å; F730-N737 PolarHBondContact N-OD1 2.81Å; F730-N737 PolarHBondContact O-ND2 3.41Å; F730-N737 PolarHBondContact O-OD1 3.42Å; F730-T773 WeakPolarHBondContact O-CB 3.11Å; F730-T773 PolarHBondContact O-OG1 2.91Å
731L85.6Confident89.2Confident65 Ų6533.8 Ų33.834%0.3417%0.171SC..SBendtrans-60.2120.5171.9-171.8109.6000111E18 E775E18-L731 VanDerWaalsContact CD-N 3.33Å; E18-L731 PolarHBondContact OE1-N 3.48Å; E18-L731 WeakPolarHBondContact OE2-CB 3.32Å; E18-L731 PolarHBondContact OE2-N 3.41Å; L731-E775 HydrophobicContact CD1-CG 3.96Å
732G85.8Confident88.9Confident20 Ų2036.2 Ų36.221%0.20620%0.196CC..EExtended strand (participates in β ladder)trans164.2-153-176.800000112.6F730 C772 T773F730-G732 PolarHBondContact O-N 2.96Å; G732-C772 CarbonylContact O-C 3.57Å; G732-C772 VanDerWaalsContact O-CA 3.3Å; G732-C772 WeakPolarHBondContact O-CA 3.16Å; G732-T773 PolarHBondContact N-OG1 3.05Å; G732-T773 VanDerWaalsContact N-OG1 3.1Å; G732-T773 PolarHBondContact O-N 3.35Å; G732-T773 PolarHBondContact O-OG1 3.36Å
733T91.4Very high88.7Confident37 Ų3742.1 Ų42.123%0.22722%0.224CC..EExtended strand (participates in β ladder)trans-91.4156.3168.256.80000110.5R735 Q736 N737 A771T733-R735 PolarHBondContact O-N 3.35Å; T733-Q736 PolarHBondContact O-N 3.37Å; T733-Q736 WeakPolarHBondContact OG1-CB 3.44Å; T733-Q736 VanDerWaalsContact OG1-CG 3.23Å; T733-Q736 WeakPolarHBondContact OG1-CG 3.23Å; T733-Q736 PolarHBondContact OG1-N 3.31Å; T733-Q736 PolarHBondContact OG1-OE1 3.49Å; T733-Q736 VanDerWaalsContact OG1-OE1 3.09Å; T733-N737 PolarHBondContact O-N 3.15Å; T733-N737 VanDerWaalsContact O-N 3.09Å; T733-N737 PolarHBondContact O-ND2 2.9Å; T733-A771 CarbonylContact C-O 3.38Å; T733-A771 WeakPolarHBondContact CA-O 3.24Å
734L92.2Very high88.7Confident0 Ų043.9 Ų43.90%023%0.232CC..Hα-helixtrans-59.2-37172.6-174.362.7000111.4N737 L738 V762 L769 A771 T773 F780 I788L734-N737 WeakPolarHBondContact O-CB 3.38Å; L734-N737 PolarHBondContact O-N 2.96Å; L734-N737 VanDerWaalsContact O-N 3.14Å; L734-L738 HydrophobicContact CG-CD1 4.08Å; L734-L738 WeakPolarHBondContact O-CG 3.39Å; L734-L738 PolarHBondContact O-N 3.44Å; L734-V762 HydrophobicContact CD2-CB 4.3Å; L734-V762 HydrophobicContact CD2-CG1 3.58Å; L734-V762 HydrophobicContact CD2-CG2 3.67Å; L734-L769 PolarHBondContact N-O 3.24Å; L734-A771 PolarHBondContact N-O 3.49Å; L734-T773 HydrophobicContact CD1-CG2 4.44Å; L734-F780 HydrophobicContact CD1-CZ 4.41Å; L734-I788 HydrophobicContact CD1-CD1 3.95Å; L734-I788 HydrophobicContact CD1-CG1 4.44Å; L734-I788 HydrophobicContact CD1-CG2 4.43Å
735R94.3Very high89.1Confident108 Ų10846.4 Ų46.441%0.40825%0.25SC..Hα-helixtrans-54.9-52.7172.2-170177-175.2-114.3-5.7112.4T733 N737 L738 D739 D746 I749 L769T733-R735 PolarHBondContact O-N 3.35Å; R735-N737 PolarHBondContact O-N 2.86Å; R735-L738 PolarHBondContact O-N 3.44Å; R735-L738 VanDerWaalsContact O-N 3.15Å; R735-D739 PolarHBondContact O-N 3.15Å; R735-D746 IonicContact CZ-OD1 2.77Å; R735-D746 IonicContact NE-OD1 3.25Å; R735-D746 PolarHBondContact NE-OD1 3.36Å; R735-D746 IonicContact NH2-OD1 3.39Å; R735-D746 PolarHBondContact NH2-OD1 2.78Å; R735-I749 HydrophobicContact CG-CD1 4.12Å; R735-L769 HydrophobicContact CB-CB 4.23Å; R735-L769 PolarHBondContact N-O 2.98Å
736Q91.2Very high89.7Confident113 Ų11346.2 Ų46.253%0.52825%0.251SS..Hα-helixtrans-62.4-28.4177.9-76.2167-30.800112.8T733 D739 P740T733-Q736 PolarHBondContact O-N 3.37Å; T733-Q736 WeakPolarHBondContact OG1-CB 3.44Å; T733-Q736 VanDerWaalsContact OG1-CG 3.23Å; T733-Q736 WeakPolarHBondContact OG1-CG 3.23Å; T733-Q736 PolarHBondContact OG1-N 3.31Å; T733-Q736 PolarHBondContact OG1-OE1 3.49Å; T733-Q736 VanDerWaalsContact OG1-OE1 3.09Å; Q736-D739 CarbonylContact O-C 3.58Å; Q736-P740 WeakPolarHBondContact O-CA 3.21Å; Q736-P740 VanDerWaalsContact O-CG 3.3Å; Q736-P740 WeakPolarHBondContact O-CG 3.24Å
737N92.7Very high90.6Very high4 Ų445 Ų452%0.02125%0.254CS..Hα-helixtrans-77-29.9176.5-89.3-82.9000113.5W31 F730 T733 L734 R735 T773 R792W31-N737 WeakPolarHBondContact CH2-O 3.45Å; F730-N737 PolarHBondContact N-OD1 2.81Å; F730-N737 PolarHBondContact O-ND2 3.41Å; F730-N737 PolarHBondContact O-OD1 3.42Å; T733-N737 PolarHBondContact O-N 3.15Å; T733-N737 VanDerWaalsContact O-N 3.09Å; T733-N737 PolarHBondContact O-ND2 2.9Å; L734-N737 WeakPolarHBondContact O-CB 3.38Å; L734-N737 PolarHBondContact O-N 2.96Å; L734-N737 VanDerWaalsContact O-N 3.14Å; R735-N737 PolarHBondContact O-N 2.86Å; N737-T773 PolarHBondContact ND2-OG1 3.42Å; N737-T773 VanDerWaalsContact ND2-OG1 3.07Å; N737-R792 VanDerWaalsContact O-CZ 3.26Å; N737-R792 PolarHBondContact O-NE 2.89Å; N737-R792 PolarHBondContact O-NH2 3.35Å; N737-R792 PolarHBondContact OD1-NH2 2.98Å
738L93.6Very high91Very high6 Ų648.2 Ų48.23%0.03127%0.269CS..Hα-helixtrans-81.5-40176.9-73.2166.1000111.2L734 R735 I749 L753 L769 I788 A791 R792 L795L734-L738 HydrophobicContact CG-CD1 4.08Å; L734-L738 WeakPolarHBondContact O-CG 3.39Å; L734-L738 PolarHBondContact O-N 3.44Å; R735-L738 PolarHBondContact O-N 3.44Å; R735-L738 VanDerWaalsContact O-N 3.15Å; L738-I749 HydrophobicContact CB-CG2 4.39Å; L738-I749 HydrophobicContact CD1-CG2 3.54Å; L738-L753 HydrophobicContact CD1-CD1 4.07Å; L738-L753 HydrophobicContact CD1-CD2 4.09Å; L738-L753 HydrophobicContact CD1-CG 4.23Å; L738-L769 HydrophobicContact CD1-CD2 4.42Å; L738-I788 HydrophobicContact CD2-CG2 3.86Å; L738-A791 HydrophobicContact CD2-CB 3.87Å; L738-R792 HydrophobicContact CD2-CG 4.26Å; L738-L795 HydrophobicContact CB-CD1 4.21Å
739D93.6Very high91.5Very high13 Ų1346.4 Ų46.47%0.0726%0.26CS..  trans-140.991.3-179.6175.816.1000111.1R735 Q736 F741 G742 E743 H744 I749R735-D739 PolarHBondContact O-N 3.15Å; Q736-D739 CarbonylContact O-C 3.58Å; D739-F741 VanDerWaalsContact C-N 3.28Å; D739-F741 PolarHBondContact O-N 2.86Å; D739-F741 PolarHBondContact OD1-N 3.07Å; D739-G742 VanDerWaalsContact CG-N 3.34Å; D739-G742 PolarHBondContact OD1-N 3.11Å; D739-G742 WeakPolarHBondContact OD2-CA 3.34Å; D739-G742 PolarHBondContact OD2-N 3.03Å; D739-E743 PolarHBondContact OD1-N 2.71Å; D739-E743 PolarHBondContact OD2-N 3.18Å; D739-H744 IonicContact OD2-CD2 3.87Å; D739-H744 PolarHBondContact OD2-N 3.34Å; D739-I749 HydrophobicContact CB-CD1 4.36Å
740P89.4Confident91.8Very high34 Ų3449.7 Ų49.722%0.22127%0.272CS..SBendtrans-70.8-19.6178.7-20.232.2000114.6W31 P34 Q736W31-P740 HydrophobicContact CD2-CG 3.68Å; W31-P740 VanDerWaalsContact CE2-CG 3.46Å; W31-P740 HydrophobicContact CE3-CG 3.99Å; W31-P740 HydrophobicContact CG-CG 4.26Å; W31-P740 HydrophobicContact CH2-CG 3.82Å; W31-P740 VanDerWaalsContact CZ2-CD 3.49Å; W31-P740 HydrophobicContact CZ2-CG 3.55Å; W31-P740 HydrophobicContact CZ3-CG 4.05Å; P34-P740 HydrophobicContact CB-CB 4.1Å; P34-P740 HydrophobicContact CG-CB 4.24Å; Q736-P740 WeakPolarHBondContact O-CA 3.21Å; Q736-P740 VanDerWaalsContact O-CG 3.3Å; Q736-P740 WeakPolarHBondContact O-CG 3.24Å
741F87.8Confident92.1Very high70 Ų7053.6 Ų53.631%0.30729%0.293SS..SBendtrans-92.2-17-178.1-70.1-78.1000112.7A30 W31 P34 D739 E743A30-F741 WeakPolarHBondContact O-CZ 3.49Å; W31-F741 AromaticContact CD1-CE2 3.6Å; P34-F741 VanDerWaalsContact CD-CZ 3.5Å; P34-F741 HydrophobicContact CG-CD1 3.6Å; P34-F741 HydrophobicContact CG-CD2 4.31Å; P34-F741 HydrophobicContact CG-CE1 3.26Å; P34-F741 HydrophobicContact CG-CE2 4.03Å; P34-F741 HydrophobicContact CG-CG 4.11Å; P34-F741 HydrophobicContact CG-CZ 3.49Å; P34-F741 VanDerWaalsContact CG-CZ 3.49Å; D739-F741 VanDerWaalsContact C-N 3.28Å; D739-F741 PolarHBondContact O-N 2.86Å; D739-F741 PolarHBondContact OD1-N 3.07Å; F741-E743 VanDerWaalsContact C-N 3.31Å; F741-E743 HydrophobicContact CB-CG 3.7Å
742G89Confident92.5Very high51 Ų5150.7 Ų50.753%0.52628%0.278SS..  trans69.331.8-174.400000112.2D739D739-G742 VanDerWaalsContact CG-N 3.34Å; D739-G742 PolarHBondContact OD1-N 3.11Å; D739-G742 WeakPolarHBondContact OD2-CA 3.34Å; D739-G742 PolarHBondContact OD2-N 3.03Å
743E88.6Confident92.9Very high126 Ų12649.7 Ų49.759%0.58927%0.269SS*.  trans-76.8-22.3178.8-71.6174.5177.800112.3D739 F741D739-E743 PolarHBondContact OD1-N 2.71Å; D739-E743 PolarHBondContact OD2-N 3.18Å; F741-E743 VanDerWaalsContact C-N 3.31Å; F741-E743 HydrophobicContact CB-CG 3.7Å
744H93Very high93Very high38 Ų3852.6 Ų52.618%0.17628%0.279CS..SBendtrans-110145.7-174-63.8-66.7000113.2D739 E748 I749 L795D739-H744 IonicContact OD2-CD2 3.87Å; D739-H744 PolarHBondContact OD2-N 3.34Å; H744-E748 WeakPolarHBondContact CA-OE2 3.38Å; H744-E748 HydrophobicContact CB-CB 4.44Å; H744-E748 IonicContact CG-OE2 3.22Å; H744-E748 IonicContact ND1-OE2 2.74Å; H744-E748 PolarHBondContact ND1-OE2 2.91Å; H744-I749 HydrophobicContact CB-CG1 4.19Å; H744-L795 PolarHBondContact CE1-O 3.4Å; H744-L795 PolarHBondContact NE2-O 3.46Å
745S95.3Very high92.9Very high60 Ų6055.4 Ų55.442%0.4229%0.292SS..  trans-77.2153.8172.571.40000111.3A747 E748 I749S745-A747 PolarHBondContact O-N 2.89Å; S745-A747 VanDerWaalsContact O-N 3.12Å; S745-E748 PolarHBondContact N-OE2 3.04Å; S745-E748 WeakPolarHBondContact O-CB 3.18Å; S745-E748 PolarHBondContact O-N 3.4Å; S745-E748 WeakPolarHBondContact OG-CG 3.24Å; S745-E748 PolarHBondContact OG-N 3.38Å; S745-I749 PolarHBondContact O-N 2.94Å; S745-I749 VanDerWaalsContact O-N 3.1Å
746D94.3Very high92.8Very high70 Ų7050.2 Ų50.237%0.37427%0.273SS..Hα-helixtrans-58.7-29.6178.7-71.16.7000112.1R735 I749 W750 L769R735-D746 IonicContact CZ-OD1 2.77Å; R735-D746 IonicContact NE-OD1 3.25Å; R735-D746 PolarHBondContact NE-OD1 3.36Å; R735-D746 IonicContact NH2-OD1 3.39Å; R735-D746 PolarHBondContact NH2-OD1 2.78Å; D746-I749 PolarHBondContact O-N 3.41Å; D746-W750 PolarHBondContact O-N 3.25Å; D746-L769 HydrophobicContact CB-CD1 4.16Å
747A94.7Very high92.7Very high73 Ų7351.8 Ų51.860%0.60327%0.274SS*.Hα-helixtrans-65.3-40.2174.700000112.4S745 W750 N751S745-A747 PolarHBondContact O-N 2.89Å; S745-A747 VanDerWaalsContact O-N 3.12Å; A747-W750 PolarHBondContact O-N 2.97Å; A747-N751 WeakPolarHBondContact O-CB 3.36Å; A747-N751 PolarHBondContact O-N 3.25Å
748E95Very high92.6Very high79 Ų7952 Ų5237%0.36928%0.275SS..Hα-helixtrans-67.4-39.4175.2-68.3173.7144.500111.4H744 S745 N751 A752 L795H744-E748 WeakPolarHBondContact CA-OE2 3.38Å; H744-E748 HydrophobicContact CB-CB 4.44Å; H744-E748 IonicContact CG-OE2 3.22Å; H744-E748 IonicContact ND1-OE2 2.74Å; H744-E748 PolarHBondContact ND1-OE2 2.91Å; S745-E748 PolarHBondContact N-OE2 3.04Å; S745-E748 WeakPolarHBondContact O-CB 3.18Å; S745-E748 PolarHBondContact O-N 3.4Å; S745-E748 WeakPolarHBondContact OG-CG 3.24Å; S745-E748 PolarHBondContact OG-N 3.38Å; E748-N751 PolarHBondContact O-N 3.05Å; E748-A752 PolarHBondContact O-N 3.44Å; E748-L795 HydrophobicContact CB-CD2 4.48Å
749I95.6Very high92.4Very high1 Ų155.3 Ų55.31%0.00529%0.289CS..Hα-helixtrans-63.5-45.8176.3-61.9175.6000110.7R735 L738 D739 H744 S745 D746 N751 A752 L753 L769 L795R735-I749 HydrophobicContact CG-CD1 4.12Å; L738-I749 HydrophobicContact CB-CG2 4.39Å; L738-I749 HydrophobicContact CD1-CG2 3.54Å; D739-I749 HydrophobicContact CB-CD1 4.36Å; H744-I749 HydrophobicContact CB-CG1 4.19Å; S745-I749 PolarHBondContact O-N 2.94Å; S745-I749 VanDerWaalsContact O-N 3.1Å; D746-I749 PolarHBondContact O-N 3.41Å; I749-N751 VanDerWaalsContact C-N 3.32Å; I749-N751 PolarHBondContact O-N 3.14Å; I749-A752 PolarHBondContact O-N 3.33Å; I749-L753 HydrophobicContact CG2-CD1 4.22Å; I749-L753 WeakPolarHBondContact O-CG 3.47Å; I749-L753 PolarHBondContact O-N 3.06Å; I749-L769 HydrophobicContact CB-CD1 4.38Å; I749-L769 HydrophobicContact CG2-CD1 4.09Å; I749-L769 HydrophobicContact CG2-CD2 3.72Å; I749-L795 HydrophobicContact CG1-CD1 4.4Å; I749-L795 HydrophobicContact CG1-CD2 4.42Å
750W96Very high92.2Very high69 Ų6962.7 Ų62.726%0.26132%0.323SS..Hα-helixtrans-64-37.1176.5-81.6117.1000112.8D746 A747 L753 E754 K759 V762 A763 L769D746-W750 PolarHBondContact O-N 3.25Å; A747-W750 PolarHBondContact O-N 2.97Å; W750-L753 HydrophobicContact CE3-CD1 4.08Å; W750-L753 HydrophobicContact CZ3-CD1 4.3Å; W750-L753 PolarHBondContact O-N 3.34Å; W750-E754 WeakPolarHBondContact O-CB 3.31Å; W750-E754 PolarHBondContact O-N 2.82Å; W750-K759 HydrophobicContact CE3-CG 3.95Å; W750-K759 HydrophobicContact CZ3-CG 4.05Å; W750-V762 HydrophobicContact CH2-CB 4.2Å; W750-V762 HydrophobicContact CH2-CG1 3.72Å; W750-V762 HydrophobicContact CZ3-CB 4.08Å; W750-V762 HydrophobicContact CZ3-CG1 3.98Å; W750-A763 HydrophobicContact CH2-CB 4.19Å; W750-A763 HydrophobicContact CZ3-CB 4.42Å; W750-L769 HydrophobicContact CD2-CG 4.49Å; W750-L769 HydrophobicContact CZ2-CD1 4.48Å; W750-L769 HydrophobicContact CZ2-CD2 4.34Å; W750-L769 HydrophobicContact CZ2-CG 3.83Å
751N94.7Very high92.1Very high88 Ų8863.3 Ų63.347%0.47133%0.327SS..Hα-helixtrans-64.4-44.1174.6-171.634.5000111.3A747 E748 I749 L753 E754 Q755A747-N751 WeakPolarHBondContact O-CB 3.36Å; A747-N751 PolarHBondContact O-N 3.25Å; E748-N751 PolarHBondContact O-N 3.05Å; I749-N751 VanDerWaalsContact C-N 3.32Å; I749-N751 PolarHBondContact O-N 3.14Å; N751-L753 VanDerWaalsContact C-N 3.32Å; N751-L753 PolarHBondContact O-N 2.89Å; N751-E754 WeakPolarHBondContact O-CB 3.42Å; N751-E754 PolarHBondContact O-N 2.92Å; N751-E754 VanDerWaalsContact O-N 3.16Å; N751-Q755 WeakPolarHBondContact O-CG 3.3Å; N751-Q755 PolarHBondContact O-N 3.08Å
752A94Very high92.2Very high4 Ų460.1 Ų60.13%0.03331%0.313CS..Hα-helixtrans-62.1-39.2174.800000112.2E748 I749 E754 Q755 V756 L794 L795E748-A752 PolarHBondContact O-N 3.44Å; I749-A752 PolarHBondContact O-N 3.33Å; A752-E754 VanDerWaalsContact C-N 3.31Å; A752-E754 PolarHBondContact O-N 3.43Å; A752-Q755 PolarHBondContact O-N 2.88Å; A752-V756 PolarHBondContact O-N 3.26Å; A752-L794 HydrophobicContact CB-CB 4.46Å; A752-L795 HydrophobicContact CB-CD2 3.72Å; A752-L795 HydrophobicContact CB-CG 3.82Å
753L94.4Very high92.3Very high0 Ų060.7 Ų60.70%031%0.312CS..Hα-helixtrans-67.8-29.2175.1-72.4174000113.3L738 I749 W750 N751 V756 R757 L758 K759 V762 L769 A791L738-L753 HydrophobicContact CD1-CD1 4.07Å; L738-L753 HydrophobicContact CD1-CD2 4.09Å; L738-L753 HydrophobicContact CD1-CG 4.23Å; I749-L753 HydrophobicContact CG2-CD1 4.22Å; I749-L753 WeakPolarHBondContact O-CG 3.47Å; I749-L753 PolarHBondContact O-N 3.06Å; W750-L753 HydrophobicContact CE3-CD1 4.08Å; W750-L753 HydrophobicContact CZ3-CD1 4.3Å; W750-L753 PolarHBondContact O-N 3.34Å; N751-L753 VanDerWaalsContact C-N 3.32Å; N751-L753 PolarHBondContact O-N 2.89Å; L753-V756 WeakPolarHBondContact O-CG2 3.46Å; L753-R757 PolarHBondContact O-N 3.42Å; L753-L758 HydrophobicContact CD2-CB 4.14Å; L753-L758 HydrophobicContact CD2-CD1 4.45Å; L753-L758 PolarHBondContact O-N 2.88Å; L753-K759 PolarHBondContact O-N 3.46Å; L753-K759 VanDerWaalsContact O-N 3.14Å; L753-V762 HydrophobicContact CD1-CB 4.39Å; L753-V762 HydrophobicContact CD1-CG1 4.18Å; L753-V762 HydrophobicContact CD1-CG2 4.22Å; L753-V762 HydrophobicContact CD2-CG2 4.37Å; L753-L769 HydrophobicContact CD1-CD2 3.59Å; L753-A791 HydrophobicContact CD2-CB 4.26Å
754E94.2Very high92.3Very high97 Ų9759.2 Ų59.245%0.45332%0.316SS..Hα-helixtrans-69.2-46174.2-169.3154.7-148.600111.4W750 N751 A752 V756 R757 K759W750-E754 WeakPolarHBondContact O-CB 3.31Å; W750-E754 PolarHBondContact O-N 2.82Å; N751-E754 WeakPolarHBondContact O-CB 3.42Å; N751-E754 PolarHBondContact O-N 2.92Å; N751-E754 VanDerWaalsContact O-N 3.16Å; A752-E754 VanDerWaalsContact C-N 3.31Å; A752-E754 PolarHBondContact O-N 3.43Å; E754-V756 VanDerWaalsContact C-N 3.26Å; E754-V756 PolarHBondContact O-N 3.34Å; E754-R757 PolarHBondContact O-N 3.47Å; E754-K759 HydrophobicContact CB-CB 4.42Å; E754-K759 HydrophobicContact CB-CD 3.88Å; E754-K759 HydrophobicContact CG-CD 3.9Å; E754-K759 IonicContact OE1-NZ 2.96Å; E754-K759 PolarHBondContact OE1-NZ 3.01Å; E754-K759 IonicContact OE2-NZ 2.91Å; E754-K759 PolarHBondContact OE2-NZ 3.05Å
755Q90.8Very high92Very high59 Ų5959.9 Ų59.928%0.27632%0.321SS..Hα-helixtrans-59.1-36.5178-70.5177.9-32.500112.5N751 A752 R757 L794 E825N751-Q755 WeakPolarHBondContact O-CG 3.3Å; N751-Q755 PolarHBondContact O-N 3.08Å; A752-Q755 PolarHBondContact O-N 2.88Å; Q755-R757 VanDerWaalsContact C-N 3.31Å; Q755-L794 HydrophobicContact CB-CD1 3.91Å; Q755-E825 HydrophobicContact CB-CG 4.45Å; Q755-E825 PolarHBondContact NE2-OE2 3.1Å
756V91.4Very high91.2Very high0 Ų062.7 Ų62.70%034%0.34CS..THydrogen-bonded Turntrans-88.69.1175.8-54.10000114A752 L753 E754 L758 L787 L790 A791 L794 T821A752-V756 PolarHBondContact O-N 3.26Å; L753-V756 WeakPolarHBondContact O-CG2 3.46Å; E754-V756 VanDerWaalsContact C-N 3.26Å; E754-V756 PolarHBondContact O-N 3.34Å; V756-L758 HydrophobicContact CG2-CB 3.94Å; V756-L758 HydrophobicContact CG2-CD1 4.09Å; V756-L758 HydrophobicContact CG2-CG 4.02Å; V756-L758 PolarHBondContact O-N 3.14Å; V756-L787 HydrophobicContact CB-CD2 4.35Å; V756-L790 HydrophobicContact CB-CD2 4.49Å; V756-L790 HydrophobicContact CG1-CB 4.03Å; V756-L790 HydrophobicContact CG1-CD2 3.84Å; V756-L790 HydrophobicContact CG1-CG 3.77Å; V756-A791 HydrophobicContact CG1-CB 4.27Å; V756-A791 HydrophobicContact CG2-CB 4.13Å; V756-L794 HydrophobicContact CG1-CD1 3.55Å; V756-T821 HydrophobicContact CG1-CG2 4.35Å
757R89.8Confident90.7Very high146 Ų14664.6 Ų64.655%0.55135%0.351SS*.THydrogen-bonded Turntrans54.729.9-177.4-53.9-167.6-173.11505.1115.1L753 E754 Q755 L817 E820L753-R757 PolarHBondContact O-N 3.42Å; E754-R757 PolarHBondContact O-N 3.47Å; Q755-R757 VanDerWaalsContact C-N 3.31Å; R757-L817 HydrophobicContact CB-CD1 4.31Å; R757-L817 HydrophobicContact CB-CD2 4.22Å; R757-L817 VanDerWaalsContact CD-CD1 3.45Å; R757-L817 HydrophobicContact CG-CD1 3.86Å; R757-E820 IonicContact CZ-OE2 2.75Å; R757-E820 IonicContact NH1-OE2 3.98Å; R757-E820 PolarHBondContact NH1-OE2 3.16Å; R757-E820 IonicContact NH2-OE1 3.36Å; R757-E820 PolarHBondContact NH2-OE1 3.4Å; R757-E820 IonicContact NH2-OE2 3.97Å; R757-E820 PolarHBondContact NH2-OE2 3.21Å
758L89.9Confident90.5Very high7 Ų761.7 Ų61.74%0.03733%0.328CS..  trans-98.1-6.3173.9-79.2-177.8000114.2L753 V756 E760 T761 V762 Q784 L787 I788L753-L758 HydrophobicContact CD2-CB 4.14Å; L753-L758 HydrophobicContact CD2-CD1 4.45Å; L753-L758 PolarHBondContact O-N 2.88Å; V756-L758 HydrophobicContact CG2-CB 3.94Å; V756-L758 HydrophobicContact CG2-CD1 4.09Å; V756-L758 HydrophobicContact CG2-CG 4.02Å; V756-L758 PolarHBondContact O-N 3.14Å; L758-E760 PolarHBondContact O-N 3.31Å; L758-T761 PolarHBondContact O-N 3.17Å; L758-V762 HydrophobicContact CB-CG2 4.44Å; L758-V762 WeakPolarHBondContact O-CG2 3.47Å; L758-V762 PolarHBondContact O-N 3.1Å; L758-Q784 HydrophobicContact CD2-CG 4.23Å; L758-L787 HydrophobicContact CD1-CB 3.44Å; L758-L787 VanDerWaalsContact CD1-CB 3.44Å; L758-L787 HydrophobicContact CD2-CB 4.3Å; L758-L787 HydrophobicContact CD2-CD1 3.88Å; L758-L787 HydrophobicContact CG-CB 3.77Å; L758-L787 HydrophobicContact CG-CD1 4Å; L758-I788 HydrophobicContact CD1-CG1 3.68Å
759K90Very high90.3Very high76 Ų7658.5 Ų58.533%0.3331%0.313SS..Hα-helixtrans-52.6-48-176.1-178.9171.4179.8179.80113.3W750 L753 E754 V762 A763W750-K759 HydrophobicContact CE3-CG 3.95Å; W750-K759 HydrophobicContact CZ3-CG 4.05Å; L753-K759 PolarHBondContact O-N 3.46Å; L753-K759 VanDerWaalsContact O-N 3.14Å; E754-K759 HydrophobicContact CB-CB 4.42Å; E754-K759 HydrophobicContact CB-CD 3.88Å; E754-K759 HydrophobicContact CG-CD 3.9Å; E754-K759 IonicContact OE1-NZ 2.96Å; E754-K759 PolarHBondContact OE1-NZ 3.01Å; E754-K759 IonicContact OE2-NZ 2.91Å; E754-K759 PolarHBondContact OE2-NZ 3.05Å; K759-V762 PolarHBondContact O-N 3.44Å; K759-A763 WeakPolarHBondContact O-CB 3.43Å; K759-A763 PolarHBondContact O-N 3.49Å
760E89.1Confident90Very high169 Ų16960.1 Ų60.179%0.7933%0.33SS*.Hα-helixtrans-65.5-44.3-179.3-63.7-178.417900112L758 V762 A763 S764L758-E760 PolarHBondContact O-N 3.31Å; E760-V762 PolarHBondContact O-N 3.1Å; E760-A763 PolarHBondContact O-N 2.99Å; E760-S764 WeakPolarHBondContact O-CB 3.41Å; E760-S764 PolarHBondContact O-N 2.87Å
761T87.2Confident89.7Confident47 Ų4757.2 Ų57.229%0.28832%0.32SS..Hα-helixtrans-58.7-48.5176.7-54.80000110.8L758 S764L758-T761 PolarHBondContact O-N 3.17Å; T761-S764 PolarHBondContact O-N 3.46Å; T761-S764 PolarHBondContact O-OG 2.9Å
762V89.6Confident89.3Confident2 Ų257 Ų571%0.01233%0.325CS..Hα-helixtrans-68.8-39.1180177.50000111.3L734 W750 L753 L758 K759 E760 S764 L765 G768 L769L734-V762 HydrophobicContact CD2-CB 4.3Å; L734-V762 HydrophobicContact CD2-CG1 3.58Å; L734-V762 HydrophobicContact CD2-CG2 3.67Å; W750-V762 HydrophobicContact CH2-CB 4.2Å; W750-V762 HydrophobicContact CH2-CG1 3.72Å; W750-V762 HydrophobicContact CZ3-CB 4.08Å; W750-V762 HydrophobicContact CZ3-CG1 3.98Å; L753-V762 HydrophobicContact CD1-CB 4.39Å; L753-V762 HydrophobicContact CD1-CG1 4.18Å; L753-V762 HydrophobicContact CD1-CG2 4.22Å; L753-V762 HydrophobicContact CD2-CG2 4.37Å; L758-V762 HydrophobicContact CB-CG2 4.44Å; L758-V762 WeakPolarHBondContact O-CG2 3.47Å; L758-V762 PolarHBondContact O-N 3.1Å; K759-V762 PolarHBondContact O-N 3.44Å; E760-V762 PolarHBondContact O-N 3.1Å; V762-S764 PolarHBondContact O-N 3.21Å; V762-L765 WeakPolarHBondContact O-CB 3.35Å; V762-L765 PolarHBondContact O-N 3.38Å; V762-L765 VanDerWaalsContact O-N 3.14Å; V762-G768 WeakPolarHBondContact O-CA 3.32Å; V762-L769 HydrophobicContact CG1-CD2 4.29Å
763A90Very high89Confident63 Ų6357 Ų5752%0.52133%0.325SS..Hα-helixtrans-64.6-28.4175.900000112.8W750 K759 E760 L765W750-A763 HydrophobicContact CH2-CB 4.19Å; W750-A763 HydrophobicContact CZ3-CB 4.42Å; K759-A763 WeakPolarHBondContact O-CB 3.43Å; K759-A763 PolarHBondContact O-N 3.49Å; E760-A763 PolarHBondContact O-N 2.99Å; A763-L765 VanDerWaalsContact C-N 3.28Å; A763-L765 PolarHBondContact O-N 3.09Å
764S88.5Confident88.4Confident95 Ų9562.2 Ų62.266%0.66435%0.349SS*.THydrogen-bonded Turntrans-74.8-15175.580.30000114E760 T761 V762E760-S764 WeakPolarHBondContact O-CB 3.41Å; E760-S764 PolarHBondContact O-N 2.87Å; T761-S764 PolarHBondContact O-N 3.46Å; T761-S764 PolarHBondContact O-OG 2.9Å; V762-S764 PolarHBondContact O-N 3.21Å
765L87.1Confident87.4Confident53 Ų5362.6 Ų62.628%0.27735%0.351SS..SBendtrans-72.8144.3175.4-59.7174.9000110V762 A763 N767 G768 A771 F780V762-L765 WeakPolarHBondContact O-CB 3.35Å; V762-L765 PolarHBondContact O-N 3.38Å; V762-L765 VanDerWaalsContact O-N 3.14Å; A763-L765 VanDerWaalsContact C-N 3.28Å; A763-L765 PolarHBondContact O-N 3.09Å; L765-N767 PolarHBondContact O-N 3.41Å; L765-G768 PolarHBondContact O-N 2.98Å; L765-G768 VanDerWaalsContact O-N 3.08Å; L765-A771 HydrophobicContact CB-CB 3.96Å; L765-A771 HydrophobicContact CD1-CB 3.79Å; L765-A771 HydrophobicContact CG-CB 4.49Å; L765-F780 HydrophobicContact CD1-CE1 4.06Å; L765-F780 HydrophobicContact CD1-CZ 3.96Å
766S78.9Confident86.6Confident119 Ų11961.2 Ų61.283%0.83235%0.352SS*.THydrogen-bonded Turntrans-54.8-22.4-170.959.10000115.5
767N85Confident86Confident110 Ų11061.2 Ų61.259%0.58835%0.352SS*.THydrogen-bonded Turntrans-130.214.5179.9-71.1-15000114L765 L769 G770L765-N767 PolarHBondContact O-N 3.41Å; N767-L769 PolarHBondContact O-N 3.49Å; N767-G770 WeakPolarHBondContact O-CA 3.43Å; N767-G770 PolarHBondContact O-N 3.42Å
768G89.6Confident85.4Confident12 Ų1262 Ų6212%0.12436%0.362CS..G310 helixtrans53.8-124.1-177.100000113.1V762 L765 G770 A771V762-G768 WeakPolarHBondContact O-CA 3.32Å; L765-G768 PolarHBondContact O-N 2.98Å; L765-G768 VanDerWaalsContact O-N 3.08Å; G768-G770 PolarHBondContact O-N 2.86Å; G768-A771 WeakPolarHBondContact O-CB 3.41Å; G768-A771 PolarHBondContact O-N 3.48Å
769L90.6Very high85Confident12 Ų1264.6 Ų64.66%0.06338%0.376CS..G310 helixtrans-62.2-23.4176-64.2-179.6000114.1L734 R735 L738 D746 I749 W750 L753 V762 N767 A771L734-L769 PolarHBondContact N-O 3.24Å; R735-L769 HydrophobicContact CB-CB 4.23Å; R735-L769 PolarHBondContact N-O 2.98Å; L738-L769 HydrophobicContact CD1-CD2 4.42Å; D746-L769 HydrophobicContact CB-CD1 4.16Å; I749-L769 HydrophobicContact CB-CD1 4.38Å; I749-L769 HydrophobicContact CG2-CD1 4.09Å; I749-L769 HydrophobicContact CG2-CD2 3.72Å; W750-L769 HydrophobicContact CD2-CG 4.49Å; W750-L769 HydrophobicContact CZ2-CD1 4.48Å; W750-L769 HydrophobicContact CZ2-CD2 4.34Å; W750-L769 HydrophobicContact CZ2-CG 3.83Å; L753-L769 HydrophobicContact CD1-CD2 3.59Å; V762-L769 HydrophobicContact CG1-CD2 4.29Å; N767-L769 PolarHBondContact O-N 3.49Å; L769-A771 VanDerWaalsContact C-N 3.25Å; L769-A771 PolarHBondContact O-N 3.44Å
770G90.2Very high84.7Confident34 Ų3461.7 Ų61.735%0.35136%0.363SS..G310 helixtrans-82.52.5175.400000113.8N767 G768N767-G770 WeakPolarHBondContact O-CA 3.43Å; N767-G770 PolarHBondContact O-N 3.42Å; G768-G770 PolarHBondContact O-N 2.86Å
771A88.9Confident84.3Confident8 Ų856.6 Ų56.67%0.06635%0.346CS..PPolyproline II helixtrans-60.7136.617600000111T733 L734 L765 G768 L769T733-A771 CarbonylContact C-O 3.38Å; T733-A771 WeakPolarHBondContact CA-O 3.24Å; L734-A771 PolarHBondContact N-O 3.49Å; L765-A771 HydrophobicContact CB-CB 3.96Å; L765-A771 HydrophobicContact CD1-CB 3.79Å; L765-A771 HydrophobicContact CG-CB 4.49Å; G768-A771 WeakPolarHBondContact O-CB 3.41Å; G768-A771 PolarHBondContact O-N 3.48Å; L769-A771 VanDerWaalsContact C-N 3.25Å; L769-A771 PolarHBondContact O-N 3.44Å
772C87Confident83.9Confident85 Ų8557 Ų5757%0.57435%0.348SS*.EExtended strand (participates in β ladder)trans-75.2131.7179.2-64.90000110.9G732 N779G732-C772 CarbonylContact O-C 3.57Å; G732-C772 VanDerWaalsContact O-CA 3.3Å; G732-C772 WeakPolarHBondContact O-CA 3.16Å; C772-N779 PolarHBondContact O-ND2 3.47Å
773T86.4Confident83.5Confident3 Ų357.2 Ų57.22%0.01835%0.351CS..EExtended strand (participates in β ladder)trans-89.4131167.447.80000108.9L729 F730 G732 L734 N737 F780L729-T773 HydrophobicContact CD1-CG2 4.49Å; F730-T773 WeakPolarHBondContact O-CB 3.11Å; F730-T773 PolarHBondContact O-OG1 2.91Å; G732-T773 PolarHBondContact N-OG1 3.05Å; G732-T773 VanDerWaalsContact N-OG1 3.1Å; G732-T773 PolarHBondContact O-N 3.35Å; G732-T773 PolarHBondContact O-OG1 3.36Å; L734-T773 HydrophobicContact CD1-CG2 4.44Å; N737-T773 PolarHBondContact ND2-OG1 3.42Å; N737-T773 VanDerWaalsContact ND2-OG1 3.07Å; T773-F780 HydrophobicContact CG2-CE2 3.94Å
774H82.8Confident83.4Confident109 Ų10956.8 Ų56.851%0.50534%0.338SS..PPolyproline II helixtrans-80.5169.1172.6-66.2164.8000110.9G776 G777 N779H774-G776 PolarHBondContact O-N 3.16Å; H774-G777 PolarHBondContact O-N 2.87Å; H774-N779 PolarHBondContact N-OD1 2.92Å
775E72.6Confident83.4Confident106 Ų10655.1 Ų55.150%0.49532%0.318SS..G310 helixtrans-49.8124.5179.7-64.1-173.5163.300110.9S14 L731 G777 Q778S14-E775 PolarHBondContact OG-OE1 3.03Å; L731-E775 HydrophobicContact CD1-CG 3.96Å; E775-G777 PolarHBondContact O-N 3.07Å; E775-G777 VanDerWaalsContact O-N 3.1Å; E775-Q778 WeakPolarHBondContact O-CG 3.13Å
776G74Confident83.5Confident29 Ų2952.9 Ų52.930%0.29931%0.306SS..G310 helixtrans66.84.5-178.200000116.1E18 L729 H774 R785E18-G776 PolarHBondContact OE1-N 3.23Å; E18-G776 VanDerWaalsContact OE1-N 3.11Å; L729-G776 CarbonylContact O-C 3.58Å; L729-G776 VanDerWaalsContact O-CA 3.23Å; L729-G776 WeakPolarHBondContact O-CA 3.39Å; L729-G776 PolarHBondContact O-N 3.02Å; H774-G776 PolarHBondContact O-N 3.16Å; G776-R785 PolarHBondContact O-NH1 3.03Å
777G78.2Confident84.1Confident0 Ų047.6 Ų47.60%027%0.268CS..G310 helixtrans77.527.7-17900000115.1H774 E775 N779 F780H774-G777 PolarHBondContact O-N 2.87Å; E775-G777 PolarHBondContact O-N 3.07Å; E775-G777 VanDerWaalsContact O-N 3.1Å; G777-N779 PolarHBondContact O-N 2.94Å; G777-F780 PolarHBondContact O-N 3.34Å
778Q77.2Confident84.5Confident164 Ų16442.4 Ų42.477%0.76624%0.24SC*.THydrogen-bonded Turntrans-56.1-18.7-178.5-71.9178.45.600114.9E775 F780E775-Q778 WeakPolarHBondContact O-CG 3.13Å; Q778-F780 PolarHBondContact O-N 3.29Å
779N82.9Confident84.6Confident61 Ų6141.9 Ų41.933%0.32623%0.234SC..THydrogen-bonded Turntrans-78.2-2.7174.860.8-38.2000114.4C772 H774 G777C772-N779 PolarHBondContact O-ND2 3.47Å; H774-N779 PolarHBondContact N-OD1 2.92Å; G777-N779 PolarHBondContact O-N 2.94Å
780F82.5Confident84.7Confident14 Ų1441.3 Ų41.36%0.06123%0.232CC..SBendtrans-121.1142.9177-65.2-83.7000110.7L729 L734 L765 T773 G777 Q778 Q784 R785 I788L729-F780 HydrophobicContact CD1-CD2 3.74Å; L729-F780 HydrophobicContact CD1-CE2 4.29Å; L729-F780 HydrophobicContact CD1-CG 4.31Å; L734-F780 HydrophobicContact CD1-CZ 4.41Å; L765-F780 HydrophobicContact CD1-CE1 4.06Å; L765-F780 HydrophobicContact CD1-CZ 3.96Å; T773-F780 HydrophobicContact CG2-CE2 3.94Å; G777-F780 PolarHBondContact O-N 3.34Å; Q778-F780 PolarHBondContact O-N 3.29Å; F780-Q784 HydrophobicContact CB-CB 4.12Å; F780-Q784 HydrophobicContact CD1-CB 4.32Å; F780-R785 HydrophobicContact CB-CG 3.77Å; F780-I788 HydrophobicContact CD1-CD1 4.07Å; F780-I788 HydrophobicContact CD2-CD1 4.5Å; F780-I788 HydrophobicContact CE1-CD1 4.25Å; F780-I788 HydrophobicContact CG-CD1 4.19Å
781S80.8Confident84.9Confident63 Ų6339.7 Ų39.744%0.44122%0.215SC..  trans-63.4159.3173.277.20000111G783 Q784 R785S781-G783 VanDerWaalsContact C-N 3.26Å; S781-G783 PolarHBondContact O-N 3.35Å; S781-Q784 PolarHBondContact O-N 2.87Å; S781-Q784 VanDerWaalsContact O-N 3.14Å; S781-Q784 VanDerWaalsContact OG-CG 3.29Å; S781-Q784 WeakPolarHBondContact OG-CG 3.33Å; S781-Q784 PolarHBondContact OG-N 2.88Å; S781-Q784 VanDerWaalsContact OG-N 3.15Å; S781-R785 WeakPolarHBondContact O-CG 3.31Å; S781-R785 PolarHBondContact O-N 3.35Å
782V79Confident85.2Confident54 Ų5439.5 Ų39.533%0.32721%0.213SC..Hα-helixtrans-53.7-45.7175.9-178.80000110.9Q784 R785 Q786 N809V782-Q784 PolarHBondContact O-N 3.24Å; V782-R785 VanDerWaalsContact CG2-NH2 3.28Å; V782-R785 PolarHBondContact O-N 3.02Å; V782-Q786 PolarHBondContact O-N 3.45Å; V782-N809 HydrophobicContact CG1-CB 4.03Å; V782-N809 WeakPolarHBondContact CG1-O 3.24Å
783G80.6Confident85.5Confident7 Ų735.5 Ų35.57%0.07219%0.186CC..Hα-helixtrans-62-41.6176.800000113.5S781 Q786 L787S781-G783 VanDerWaalsContact C-N 3.26Å; S781-G783 PolarHBondContact O-N 3.35Å; G783-Q786 WeakPolarHBondContact O-CB 3.29Å; G783-Q786 PolarHBondContact O-N 3.06Å; G783-L787 WeakPolarHBondContact O-CG 3.36Å; G783-L787 PolarHBondContact O-N 2.92Å
784Q87.9Confident85.8Confident55 Ų5536.1 Ų36.126%0.25719%0.189SC..Hα-helixtrans-64.8-41.1175.4-73.5168.5-13.300112L758 F780 S781 V782 Q786 L787 I788L758-Q784 HydrophobicContact CD2-CG 4.23Å; F780-Q784 HydrophobicContact CB-CB 4.12Å; F780-Q784 HydrophobicContact CD1-CB 4.32Å; S781-Q784 PolarHBondContact O-N 2.87Å; S781-Q784 VanDerWaalsContact O-N 3.14Å; S781-Q784 VanDerWaalsContact OG-CG 3.29Å; S781-Q784 WeakPolarHBondContact OG-CG 3.33Å; S781-Q784 PolarHBondContact OG-N 2.88Å; S781-Q784 VanDerWaalsContact OG-N 3.15Å; V782-Q784 PolarHBondContact O-N 3.24Å; Q784-Q786 VanDerWaalsContact C-N 3.25Å; Q784-Q786 PolarHBondContact O-N 3.01Å; Q784-L787 PolarHBondContact O-N 2.86Å; Q784-I788 VanDerWaalsContact O-CG1 3.3Å; Q784-I788 WeakPolarHBondContact O-CG1 3.24Å; Q784-I788 PolarHBondContact O-N 2.78Å
785R89.6Confident86.3Confident60 Ų6031.5 Ų31.523%0.22617%0.167CC..Hα-helixtrans-60.1-38.7174.5-69.4-174.7-78.2166.2-0.9111.2P727 L729 G776 F780 S781 V782 I788 C789P727-R785 HydrophobicContact CB-CB 3.84Å; P727-R785 HydrophobicContact CG-CB 3.72Å; L729-R785 HydrophobicContact CD1-CG 3.96Å; L729-R785 HydrophobicContact CG-CG 4.27Å; G776-R785 PolarHBondContact O-NH1 3.03Å; F780-R785 HydrophobicContact CB-CG 3.77Å; S781-R785 WeakPolarHBondContact O-CG 3.31Å; S781-R785 PolarHBondContact O-N 3.35Å; V782-R785 VanDerWaalsContact CG2-NH2 3.28Å; V782-R785 PolarHBondContact O-N 3.02Å; R785-I788 PolarHBondContact O-N 2.88Å; R785-C789 PolarHBondContact O-N 2.81Å
786Q89.1Confident87.1Confident5 Ų528.9 Ų28.92%0.02315%0.153CC..Hα-helixtrans-64.8-44.7176-155.965.66.200112.7P724 P727 V782 G783 Q784 I788 C789 L790 A806 V810 I818P724-Q786 PolarHBondContact O-NE2 3.15Å; P727-Q786 VanDerWaalsContact CB-OE1 3.28Å; V782-Q786 PolarHBondContact O-N 3.45Å; G783-Q786 WeakPolarHBondContact O-CB 3.29Å; G783-Q786 PolarHBondContact O-N 3.06Å; Q784-Q786 VanDerWaalsContact C-N 3.25Å; Q784-Q786 PolarHBondContact O-N 3.01Å; Q786-I788 VanDerWaalsContact C-N 3.3Å; Q786-I788 PolarHBondContact O-N 3.5Å; Q786-C789 WeakPolarHBondContact O-CB 3.06Å; Q786-C789 PolarHBondContact O-N 3.4Å; Q786-C789 VanDerWaalsContact O-N 3.14Å; Q786-L790 PolarHBondContact O-N 3.44Å; Q786-A806 VanDerWaalsContact CG-O 3.29Å; Q786-A806 WeakPolarHBondContact CG-O 3.25Å; Q786-A806 VanDerWaalsContact NE2-CB 3.3Å; Q786-A806 PolarHBondContact NE2-O 3.4Å; Q786-V810 HydrophobicContact CB-CG2 4.34Å; Q786-V810 HydrophobicContact CG-CG2 4.34Å; Q786-I818 HydrophobicContact CB-CD1 4.13Å; Q786-I818 HydrophobicContact CG-CD1 3.75Å
787L91.3Very high87.8Confident9 Ų935.3 Ų35.35%0.04717%0.173CC..Hα-helixtrans-64.2-33.9175.2-69.2171.9000112.1V756 L758 G783 Q784 L790 A791 T814 L817 I818V756-L787 HydrophobicContact CB-CD2 4.35Å; L758-L787 HydrophobicContact CD1-CB 3.44Å; L758-L787 VanDerWaalsContact CD1-CB 3.44Å; L758-L787 HydrophobicContact CD2-CB 4.3Å; L758-L787 HydrophobicContact CD2-CD1 3.88Å; L758-L787 HydrophobicContact CG-CB 3.77Å; L758-L787 HydrophobicContact CG-CD1 4Å; G783-L787 WeakPolarHBondContact O-CG 3.36Å; G783-L787 PolarHBondContact O-N 2.92Å; Q784-L787 PolarHBondContact O-N 2.86Å; L787-L790 HydrophobicContact CD2-CD2 4.32Å; L787-L790 WeakPolarHBondContact O-CB 3.4Å; L787-L790 PolarHBondContact O-N 3.33Å; L787-A791 PolarHBondContact O-N 2.88Å; L787-T814 HydrophobicContact CD1-CG2 4.27Å; L787-T814 HydrophobicContact CG-CG2 4.42Å; L787-L817 HydrophobicContact CD1-CD2 4Å; L787-L817 HydrophobicContact CD2-CD2 4.07Å; L787-L817 HydrophobicContact CD2-CG 4.31Å; L787-I818 HydrophobicContact CD2-CG1 3.75Å
788I93Very high88.5Confident1 Ų136 Ų361%0.00518%0.177CC..Hα-helixtrans-64.7-41.4171.7-67.8163.8000110.7L729 L734 L738 L758 F780 Q784 R785 Q786 L790 A791 R792L729-I788 HydrophobicContact CD1-CD1 3.79Å; L729-I788 HydrophobicContact CD2-CB 4.32Å; L729-I788 HydrophobicContact CD2-CG2 3.62Å; L734-I788 HydrophobicContact CD1-CD1 3.95Å; L734-I788 HydrophobicContact CD1-CG1 4.44Å; L734-I788 HydrophobicContact CD1-CG2 4.43Å; L738-I788 HydrophobicContact CD2-CG2 3.86Å; L758-I788 HydrophobicContact CD1-CG1 3.68Å; F780-I788 HydrophobicContact CD1-CD1 4.07Å; F780-I788 HydrophobicContact CD2-CD1 4.5Å; F780-I788 HydrophobicContact CE1-CD1 4.25Å; F780-I788 HydrophobicContact CG-CD1 4.19Å; Q784-I788 VanDerWaalsContact O-CG1 3.3Å; Q784-I788 WeakPolarHBondContact O-CG1 3.24Å; Q784-I788 PolarHBondContact O-N 2.78Å; R785-I788 PolarHBondContact O-N 2.88Å; Q786-I788 VanDerWaalsContact C-N 3.3Å; Q786-I788 PolarHBondContact O-N 3.5Å; I788-L790 VanDerWaalsContact C-N 3.32Å; I788-L790 PolarHBondContact O-N 2.78Å; I788-A791 WeakPolarHBondContact O-CB 3.4Å; I788-A791 PolarHBondContact O-N 2.83Å; I788-R792 WeakPolarHBondContact O-CG 3.45Å; I788-R792 PolarHBondContact O-N 3.45Å
789C92.6Very high89.3Confident0 Ų033.6 Ų33.60%016%0.16CC..Hα-helixtrans-63.5-36.8172.9-71.90000112.6I723 P727 R785 Q786 R792 A793I723-C789 HydrophobicContact CG2-CB 4.31Å; P727-C789 VanDerWaalsContact CB-SG 3.57Å; R785-C789 PolarHBondContact O-N 2.81Å; Q786-C789 WeakPolarHBondContact O-CB 3.06Å; Q786-C789 PolarHBondContact O-N 3.4Å; Q786-C789 VanDerWaalsContact O-N 3.14Å; C789-R792 WeakPolarHBondContact O-CB 3.49Å; C789-R792 PolarHBondContact O-N 3.43Å; C789-A793 PolarHBondContact O-N 3.42Å; C789-A793 VanDerWaalsContact O-N 3.09Å
790L92.5Very high89.9Confident1 Ų130.7 Ų30.71%0.00515%0.145CC..Hα-helixtrans-63.9-41.1173.3-173.362.9000111.4I723 V756 Q786 L787 I788 R792 A793 L794 T821 I822 F826I723-L790 HydrophobicContact CD1-CB 4.26Å; I723-L790 HydrophobicContact CD1-CD1 3.4Å; I723-L790 VanDerWaalsContact CD1-CD1 3.4Å; I723-L790 HydrophobicContact CD1-CG 4.43Å; V756-L790 HydrophobicContact CB-CD2 4.49Å; V756-L790 HydrophobicContact CG1-CB 4.03Å; V756-L790 HydrophobicContact CG1-CD2 3.84Å; V756-L790 HydrophobicContact CG1-CG 3.77Å; Q786-L790 PolarHBondContact O-N 3.44Å; L787-L790 HydrophobicContact CD2-CD2 4.32Å; L787-L790 WeakPolarHBondContact O-CB 3.4Å; L787-L790 PolarHBondContact O-N 3.33Å; I788-L790 VanDerWaalsContact C-N 3.32Å; I788-L790 PolarHBondContact O-N 2.78Å; L790-R792 VanDerWaalsContact C-N 3.34Å; L790-R792 PolarHBondContact O-N 3.31Å; L790-A793 WeakPolarHBondContact O-CB 3.42Å; L790-A793 PolarHBondContact O-N 3.13Å; L790-A793 VanDerWaalsContact O-N 3.11Å; L790-L794 WeakPolarHBondContact O-CG 3.45Å; L790-L794 PolarHBondContact O-N 3.33Å; L790-T821 HydrophobicContact CD2-CG2 3.68Å; L790-T821 HydrophobicContact CG-CG2 4.37Å; L790-I822 HydrophobicContact CD1-CG1 4.15Å; L790-F826 HydrophobicContact CD1-CE2 3.76Å; L790-F826 HydrophobicContact CD1-CZ 4.32Å
791A94.5Very high90.5Very high0 Ų030.1 Ų30.10%014%0.142CC..Hα-helixtrans-61.4-39.5173.100000112.2L738 L753 V756 L787 I788 A793 L794 L795L738-A791 HydrophobicContact CD2-CB 3.87Å; L753-A791 HydrophobicContact CD2-CB 4.26Å; V756-A791 HydrophobicContact CG1-CB 4.27Å; V756-A791 HydrophobicContact CG2-CB 4.13Å; L787-A791 PolarHBondContact O-N 2.88Å; I788-A791 WeakPolarHBondContact O-CB 3.4Å; I788-A791 PolarHBondContact O-N 2.83Å; A791-A793 VanDerWaalsContact C-N 3.29Å; A791-A793 PolarHBondContact O-N 3.5Å; A791-L794 PolarHBondContact O-N 3.02Å; A791-L795 WeakPolarHBondContact O-CG 3.5Å; A791-L795 PolarHBondContact O-N 2.9Å
792R94.3Very high91.1Very high4 Ų427.1 Ų27.12%0.01512%0.122CC..Hα-helixtrans-59.3-39.5172.3-66.9170.5176.1167.1-11.6112W31 I728 N737 L738 I788 C789 L790 R796W31-R792 HydrophobicContact CH2-CG 4.45Å; I728-R792 PolarHBondContact O-NH1 3.42Å; I728-R792 PolarHBondContact O-NH2 3.38Å; N737-R792 VanDerWaalsContact O-CZ 3.26Å; N737-R792 PolarHBondContact O-NE 2.89Å; N737-R792 PolarHBondContact O-NH2 3.35Å; N737-R792 PolarHBondContact OD1-NH2 2.98Å; L738-R792 HydrophobicContact CD2-CG 4.26Å; I788-R792 WeakPolarHBondContact O-CG 3.45Å; I788-R792 PolarHBondContact O-N 3.45Å; C789-R792 WeakPolarHBondContact O-CB 3.49Å; C789-R792 PolarHBondContact O-N 3.43Å; L790-R792 VanDerWaalsContact C-N 3.34Å; L790-R792 PolarHBondContact O-N 3.31Å; R792-R796 WeakPolarHBondContact O-CG 3.4Å
793A93.2Very high91.7Very high1 Ų124.9 Ų24.91%0.00811%0.108CC..Hα-helixtrans-68.9-38.6178.600000112.2S721 I723 C789 L790 A791 L801 F826S721-A793 PolarHBondContact OG-O 3.24Å; I723-A793 HydrophobicContact CG1-CB 4.36Å; C789-A793 PolarHBondContact O-N 3.42Å; C789-A793 VanDerWaalsContact O-N 3.09Å; L790-A793 WeakPolarHBondContact O-CB 3.42Å; L790-A793 PolarHBondContact O-N 3.13Å; L790-A793 VanDerWaalsContact O-N 3.11Å; A791-A793 VanDerWaalsContact C-N 3.29Å; A791-A793 PolarHBondContact O-N 3.5Å; A793-L801 HydrophobicContact CB-CD1 4.03Å; A793-F826 HydrophobicContact CB-CE1 4.41Å; A793-F826 HydrophobicContact CB-CZ 3.96Å
794L93.2Very high92.1Very high16 Ų1625.2 Ų25.28%0.08411%0.108CC..Hα-helixtrans-65.2-43.7177-72.5169.9000112.4A752 Q755 V756 L790 A791 R796 K797 E825 F826A752-L794 HydrophobicContact CB-CB 4.46Å; Q755-L794 HydrophobicContact CB-CD1 3.91Å; V756-L794 HydrophobicContact CG1-CD1 3.55Å; L790-L794 WeakPolarHBondContact O-CG 3.45Å; L790-L794 PolarHBondContact O-N 3.33Å; A791-L794 PolarHBondContact O-N 3.02Å; L794-R796 PolarHBondContact O-N 3.48Å; L794-K797 VanDerWaalsContact O-CG 3.29Å; L794-K797 WeakPolarHBondContact O-CG 3.46Å; L794-K797 PolarHBondContact O-N 3.15Å; L794-E825 HydrophobicContact CD2-CB 3.54Å; L794-E825 HydrophobicContact CD2-CG 4.02Å; L794-F826 HydrophobicContact CD2-CD2 4.24Å; L794-F826 HydrophobicContact CD2-CE1 4.26Å; L794-F826 HydrophobicContact CD2-CE2 3.43Å; L794-F826 VanDerWaalsContact CD2-CE2 3.43Å; L794-F826 HydrophobicContact CD2-CZ 3.45Å; L794-F826 VanDerWaalsContact CD2-CZ 3.45Å; L794-F826 HydrophobicContact CG-CE2 3.94Å; L794-F826 HydrophobicContact CG-CZ 3.79Å
795L93.5Very high91.7Very high11 Ų1123.9 Ų23.96%0.05810%0.102CC..Hα-helixtrans-57.5-37179.7-75.1171.9000112.5L738 H744 E748 I749 A752 A791 K797L738-L795 HydrophobicContact CB-CD1 4.21Å; H744-L795 PolarHBondContact CE1-O 3.4Å; H744-L795 PolarHBondContact NE2-O 3.46Å; E748-L795 HydrophobicContact CB-CD2 4.48Å; I749-L795 HydrophobicContact CG1-CD1 4.4Å; I749-L795 HydrophobicContact CG1-CD2 4.42Å; A752-L795 HydrophobicContact CB-CD2 3.72Å; A752-L795 HydrophobicContact CB-CG 3.82Å; A791-L795 WeakPolarHBondContact O-CG 3.5Å; A791-L795 PolarHBondContact O-N 2.9Å; L795-K797 PolarHBondContact O-N 3.22Å
796R90.1Very high90.9Very high51 Ų5121.5 Ų21.519%0.19210%0.095CC..Hα-helixtrans-75.7-19.7-177.4-65175.771.4-164.9-1.8114.4R717 K718 I720 R792 L794 N798R717-R796 PolarHBondContact O-NH2 3.42Å; K718-R796 PolarHBondContact O-NH2 3.17Å; I720-R796 VanDerWaalsContact O-CZ 3.32Å; I720-R796 PolarHBondContact O-NH1 2.96Å; I720-R796 PolarHBondContact O-NH2 3.23Å; I720-R796 VanDerWaalsContact O-NH2 3.09Å; R792-R796 WeakPolarHBondContact O-CG 3.4Å; L794-R796 PolarHBondContact O-N 3.48Å; R796-N798 PolarHBondContact O-N 2.72Å
797K87.8Confident90.1Very high165 Ų16521.7 Ų21.772%0.71710%0.096SC*.THydrogen-bonded Turntrans47.936.7177.4-58.2-178.8-171.9174.40114.9L794 L795L794-K797 VanDerWaalsContact O-CG 3.29Å; L794-K797 WeakPolarHBondContact O-CG 3.46Å; L794-K797 PolarHBondContact O-N 3.15Å; L795-K797 PolarHBondContact O-N 3.22Å
798N92.4Very high88.8Confident15 Ų1522.7 Ų22.78%0.0811%0.106CC..  trans-76152.4-179.7-73.4-34.7000112.4K718 K719 S721 R796 I800 C829K718-N798 PolarHBondContact O-ND2 3.12Å; K718-N798 VanDerWaalsContact O-ND2 3.15Å; K718-N798 PolarHBondContact O-OD1 3.4Å; K719-N798 VanDerWaalsContact C-CG 3.41Å; K719-N798 WeakPolarHBondContact CA-OD1 3.4Å; K719-N798 WeakPolarHBondContact O-CB 3.48Å; K719-N798 VanDerWaalsContact O-CG 3.27Å; K719-N798 PolarHBondContact O-OD1 3.36Å; S721-N798 PolarHBondContact N-ND2 3Å; S721-N798 PolarHBondContact OG-ND2 3.25Å; S721-N798 VanDerWaalsContact OG-ND2 3.1Å; R796-N798 PolarHBondContact O-N 2.72Å; N798-I800 VanDerWaalsContact C-N 3.31Å; N798-I800 PolarHBondContact O-N 2.91Å; N798-C829 PolarHBondContact O-SG 3.5Å
799R93.6Very high87.5Confident112 Ų11227.4 Ų27.442%0.42313%0.131SC..SBendtrans-76.5-15.1176.5-65.8-63.5-173.5-176-2.7114.2P639 C829 S830P639-R799 HydrophobicContact CG-CB 4.43Å; P639-R799 WeakPolarHBondContact O-CG 3.35Å; R799-C829 CarbonylContact O-C 3.58Å; R799-C829 VanDerWaalsContact O-CA 3.32Å; R799-C829 WeakPolarHBondContact O-CA 3.36Å; R799-C829 WeakPolarHBondContact O-CB 3.34Å; R799-S830 PolarHBondContact O-N 3.32Å
800I95.4Very high86.5Confident1 Ų127.6 Ų27.61%0.00513%0.132CC..EExtended strand (participates in β ladder)trans-121.4124.1-178.2-55.9167.3000108.6P639 V644 I703 I720 S721 N798 S830P639-I800 HydrophobicContact CG-CD1 4.26Å; V644-I800 HydrophobicContact CG2-CD1 3.7Å; V644-I800 HydrophobicContact CG2-CG1 4.32Å; V644-I800 HydrophobicContact CG2-CG2 4.39Å; I703-I800 HydrophobicContact CD1-CD1 4.23Å; I703-I800 HydrophobicContact CG2-CD1 3.69Å; I720-I800 HydrophobicContact CG2-CB 4.43Å; I720-I800 HydrophobicContact CG2-CG2 4.05Å; S721-I800 PolarHBondContact N-O 2.89Å; N798-I800 VanDerWaalsContact C-N 3.31Å; N798-I800 PolarHBondContact O-N 2.91Å; I800-S830 WeakPolarHBondContact CA-O 3.21Å
801L95.1Very high85.5Confident1 Ų130 Ų301%0.00515%0.145CC..EExtended strand (participates in β ladder)trans-118.5129.5175.8179.866.5000110.1S721 I723 A793 L803 F826 S830 V831 L832S721-L801 CarbonylContact O-C 3.57Å; S721-L801 WeakPolarHBondContact O-CA 3.38Å; I723-L801 HydrophobicContact CG1-CD1 4.28Å; A793-L801 HydrophobicContact CB-CD1 4.03Å; L801-L803 HydrophobicContact CD1-CD2 4.32Å; L801-L803 HydrophobicContact CD2-CD2 3.93Å; L801-L803 HydrophobicContact CD2-CG 4.42Å; L801-L803 HydrophobicContact CG-CD2 3.98Å; L801-L803 HydrophobicContact CG-CG 4.39Å; L801-F826 HydrophobicContact CB-CD1 4.42Å; L801-F826 HydrophobicContact CD1-CE1 4.22Å; L801-F826 HydrophobicContact CD2-CB 4.21Å; L801-F826 HydrophobicContact CD2-CD1 3.69Å; L801-F826 HydrophobicContact CD2-CD2 4.09Å; L801-F826 HydrophobicContact CD2-CE1 3.96Å; L801-F826 HydrophobicContact CD2-CE2 4.33Å; L801-F826 HydrophobicContact CD2-CG 3.73Å; L801-F826 HydrophobicContact CD2-CZ 4.25Å; L801-F826 HydrophobicContact CG-CD1 4.47Å; L801-S830 PolarHBondContact N-O 3.1Å; L801-V831 HydrophobicContact CB-CG2 4.38Å; L801-V831 HydrophobicContact CD2-CG1 4.34Å; L801-V831 HydrophobicContact CD2-CG2 4.45Å; L801-V831 CarbonylContact O-C 3.57Å; L801-V831 WeakPolarHBondContact O-CA 3.3Å; L801-L832 PolarHBondContact O-N 3.25Å
802V94.8Very high84.6Confident0 Ų036.4 Ų36.40%018%0.179CC..EExtended strand (participates in β ladder)trans-112.7126.7175.2-176.70000109.2I688 L691 F692 I720 S721 I722 I723 L832I688-V802 HydrophobicContact CD1-CG1 3.74Å; I688-V802 HydrophobicContact CG1-CG1 3.92Å; L691-V802 HydrophobicContact CD2-CG2 3.75Å; F692-V802 HydrophobicContact CE2-CB 4.39Å; F692-V802 HydrophobicContact CE2-CG2 4.13Å; I720-V802 HydrophobicContact CG2-CG2 3.87Å; S721-V802 PolarHBondContact O-N 3.32Å; I722-V802 CarbonylContact C-O 3.44Å; I722-V802 VanDerWaalsContact CA-O 3.3Å; I722-V802 WeakPolarHBondContact CA-O 3.27Å; I722-V802 HydrophobicContact CB-CB 4.48Å; I722-V802 HydrophobicContact CD1-CG1 4.32Å; I722-V802 HydrophobicContact CG1-CB 4.33Å; I723-V802 PolarHBondContact N-O 3.27Å; V802-L832 CarbonylContact C-O 3.19Å; V802-L832 WeakPolarHBondContact CA-O 3.47Å
803L91.9Very high83.8Confident7 Ų742.7 Ų42.74%0.03721%0.212CC..EExtended strand (participates in β ladder)trans-111.3115.8177-54.4177000108.4I723 L801 A806 I822 V831 L832 T833 I834I723-L803 HydrophobicContact CB-CD2 3.86Å; I723-L803 HydrophobicContact CD1-CD2 3.48Å; I723-L803 VanDerWaalsContact CD1-CD2 3.48Å; I723-L803 HydrophobicContact CG1-CD2 3.73Å; L801-L803 HydrophobicContact CD1-CD2 4.32Å; L801-L803 HydrophobicContact CD2-CD2 3.93Å; L801-L803 HydrophobicContact CD2-CG 4.42Å; L801-L803 HydrophobicContact CG-CD2 3.98Å; L801-L803 HydrophobicContact CG-CG 4.39Å; L803-A806 HydrophobicContact CB-CB 4.5Å; L803-I822 HydrophobicContact CD1-CD1 3.78Å; L803-I822 HydrophobicContact CD2-CD1 4.25Å; L803-V831 HydrophobicContact CD1-CG1 3.87Å; L803-V831 HydrophobicContact CG-CG1 4.18Å; L803-L832 PolarHBondContact N-O 2.85Å; L803-T833 HydrophobicContact CB-CG2 4.2Å; L803-T833 HydrophobicContact CD1-CG2 4.19Å; L803-I834 PolarHBondContact O-N 2.95Å
804D88Confident83.2Confident14 Ų1443.9 Ų43.98%0.07522%0.22CC..EExtended strand (participates in β ladder)trans-105.591.5180-168.320.6000109.8I688 I723 P724 Q725 A806I688-D804 HydrophobicContact CD1-CB 3.59Å; I688-D804 VanDerWaalsContact CD1-CG 3.47Å; I723-D804 PolarHBondContact O-N 3.25Å; P724-D804 CarbonylContact C-O 3.59Å; Q725-D804 WeakPolarHBondContact CA-O 3.4Å; Q725-D804 PolarHBondContact N-O 3.36Å; D804-A806 PolarHBondContact O-N 3.28Å
805E80.7Confident82.6Confident28 Ų2843.8 Ų43.813%0.13122%0.22CC..SBendtrans48.934.6179.5-62.7-172.1-176.300114.1Q725 T807 A808 I834Q725-E805 HydrophobicContact CG-CB 4.25Å; Q725-E805 PolarHBondContact NE2-OE2 2.96Å; E805-T807 PolarHBondContact O-N 3.43Å; E805-A808 HydrophobicContact CB-CB 4.44Å; E805-A808 WeakPolarHBondContact O-CB 3.33Å; E805-A808 PolarHBondContact O-N 3.38Å; E805-A808 VanDerWaalsContact O-N 3.1Å; E805-I834 WeakPolarHBondContact CA-O 3.3Å; E805-I834 HydrophobicContact CG-CG2 4.18Å; E805-I834 PolarHBondContact N-O 3.15Å
806A72.4Confident82.1Confident10 Ų1046.9 Ų46.98%0.08324%0.242CC..THydrogen-bonded Turntrans-59-11.1-166.300000115.8I723 Q786 L803 D804I723-A806 HydrophobicContact CB-CB 4.34Å; I723-A806 HydrophobicContact CG2-CB 3.76Å; Q786-A806 VanDerWaalsContact CG-O 3.29Å; Q786-A806 WeakPolarHBondContact CG-O 3.25Å; Q786-A806 VanDerWaalsContact NE2-CB 3.3Å; Q786-A806 PolarHBondContact NE2-O 3.4Å; L803-A806 HydrophobicContact CB-CB 4.5Å; D804-A806 PolarHBondContact O-N 3.28Å
807T71.6Confident81.9Confident9 Ų945.7 Ų45.76%0.05524%0.239CC..THydrogen-bonded Turntrans-124.27.3-174.566.80000113.1E805 N809 V810 D815 I818 R837E805-T807 PolarHBondContact O-N 3.43Å; T807-N809 VanDerWaalsContact C-N 3.31Å; T807-N809 PolarHBondContact O-N 3.17Å; T807-V810 PolarHBondContact O-N 3.06Å; T807-D815 WeakPolarHBondContact CB-OD1 3.34Å; T807-D815 WeakPolarHBondContact CG2-OD1 3.41Å; T807-D815 PolarHBondContact OG1-OD1 3.32Å; T807-I818 HydrophobicContact CG2-CG2 4.17Å; T807-R837 PolarHBondContact O-NH1 3.27Å; T807-R837 PolarHBondContact O-NH2 3.04Å
808A64.3Low81.8Confident30 Ų3037.9 Ų37.925%0.24821%0.205CC..THydrogen-bonded Turntrans-60.2-39.6-177.300000112.9E805 R837E805-A808 HydrophobicContact CB-CB 4.44Å; E805-A808 WeakPolarHBondContact O-CB 3.33Å; E805-A808 PolarHBondContact O-N 3.38Å; E805-A808 VanDerWaalsContact O-N 3.1Å; A808-R837 PolarHBondContact O-NH2 2.64Å
809N65.5Low81.4Confident99 Ų9938.5 Ų38.553%0.52921%0.208SC..THydrogen-bonded Turntrans-109.824.2-172.5-62.3-25.7000113.3V782 T807V782-N809 HydrophobicContact CG1-CB 4.03Å; V782-N809 WeakPolarHBondContact CG1-O 3.24Å; T807-N809 VanDerWaalsContact C-N 3.31Å; T807-N809 PolarHBondContact O-N 3.17Å
810V71.8Confident81Confident5 Ų537.3 Ų37.33%0.0321%0.207CC..SBendtrans-119.1143-173.8-176.90000110Q786 T807 T814 I818Q786-V810 HydrophobicContact CB-CG2 4.34Å; Q786-V810 HydrophobicContact CG-CG2 4.34Å; T807-V810 PolarHBondContact O-N 3.06Å; V810-T814 HydrophobicContact CG1-CG2 3.37Å; V810-I818 HydrophobicContact CG1-CD1 4.16Å
811D72Confident80.7Confident52 Ų5237.6 Ų37.628%0.27821%0.209SC..  trans-65.2159.7176.968.773.4000112.3L183 N813 T814 D815L183-D811 HydrophobicContact CB-CB 4.4Å; L183-D811 HydrophobicContact CD1-CB 3.7Å; D811-N813 VanDerWaalsContact C-N 3.28Å; D811-N813 PolarHBondContact O-N 3.15Å; D811-N813 WeakPolarHBondContact OD1-CA 3.28Å; D811-N813 WeakPolarHBondContact OD1-CB 3.5Å; D811-N813 PolarHBondContact OD1-N 3.16Å; D811-T814 VanDerWaalsContact CG-OG1 3.28Å; D811-T814 PolarHBondContact O-N 3.4Å; D811-T814 WeakPolarHBondContact OD1-CB 3.29Å; D811-T814 PolarHBondContact OD1-N 3.43Å; D811-T814 PolarHBondContact OD1-OG1 2.88Å; D811-T814 VanDerWaalsContact OD1-OG1 3.08Å; D811-T814 PolarHBondContact OD2-OG1 2.89Å; D811-D815 VanDerWaalsContact O-CB 3.31Å; D811-D815 WeakPolarHBondContact O-CB 3.33Å; D811-D815 PolarHBondContact O-N 3.41Å
812L74.3Confident80.3Confident133 Ų13338 Ų3870%0.69621%0.211SC*.Hα-helixtrans-59.6-34.4-175.2-71.7167.7000113.6S816L812-S816 WeakPolarHBondContact O-CB 3.44Å; L812-S816 PolarHBondContact O-N 2.69Å; L812-S816 PolarHBondContact O-OG 2.93Å
813N77.1Confident79.9Confident136 Ų13644.1 Ų44.173%0.72723%0.234SC*.Hα-helixtrans-72.2-45.3-179.1-66.4-28.9000110.5D811 S816 L817D811-N813 VanDerWaalsContact C-N 3.28Å; D811-N813 PolarHBondContact O-N 3.15Å; D811-N813 WeakPolarHBondContact OD1-CA 3.28Å; D811-N813 WeakPolarHBondContact OD1-CB 3.5Å; D811-N813 PolarHBondContact OD1-N 3.16Å; N813-S816 WeakPolarHBondContact O-CB 3.34Å; N813-S816 PolarHBondContact O-N 3Å; N813-L817 PolarHBondContact O-N 3.32Å
814T80.6Confident79.7Confident26 Ų2648.2 Ų48.216%0.1626%0.259CS..Hα-helixtrans-70.4-36.2178.4-54.20000111.1L787 V810 D811 L817 I818L787-T814 HydrophobicContact CD1-CG2 4.27Å; L787-T814 HydrophobicContact CG-CG2 4.42Å; V810-T814 HydrophobicContact CG1-CG2 3.37Å; D811-T814 VanDerWaalsContact CG-OG1 3.28Å; D811-T814 PolarHBondContact O-N 3.4Å; D811-T814 WeakPolarHBondContact OD1-CB 3.29Å; D811-T814 PolarHBondContact OD1-N 3.43Å; D811-T814 PolarHBondContact OD1-OG1 2.88Å; D811-T814 VanDerWaalsContact OD1-OG1 3.08Å; D811-T814 PolarHBondContact OD2-OG1 2.89Å; T814-L817 WeakPolarHBondContact O-CB 3.43Å; T814-L817 PolarHBondContact O-N 3.13Å; T814-I818 HydrophobicContact CG2-CD1 4.15Å; T814-I818 VanDerWaalsContact O-CG1 3.27Å; T814-I818 WeakPolarHBondContact O-CG1 3.12Å; T814-I818 PolarHBondContact O-N 3.31Å
815D82.2Confident79.7Confident15 Ų1551.1 Ų51.18%0.0827%0.272CS..Hα-helixtrans-59.8-48171-17520.3000110.8T807 D811 L817 I818 Q819 R837T807-D815 WeakPolarHBondContact CB-OD1 3.34Å; T807-D815 WeakPolarHBondContact CG2-OD1 3.41Å; T807-D815 PolarHBondContact OG1-OD1 3.32Å; D811-D815 VanDerWaalsContact O-CB 3.31Å; D811-D815 WeakPolarHBondContact O-CB 3.33Å; D811-D815 PolarHBondContact O-N 3.41Å; D815-L817 VanDerWaalsContact C-N 3.29Å; D815-L817 PolarHBondContact O-N 2.89Å; D815-I818 PolarHBondContact O-N 3.39Å; D815-I818 VanDerWaalsContact O-N 3.15Å; D815-Q819 WeakPolarHBondContact O-CB 3.42Å; D815-Q819 WeakPolarHBondContact O-CG 3.26Å; D815-Q819 PolarHBondContact O-N 2.82Å; D815-R837 IonicContact OD2-NH1 3.04Å; D815-R837 PolarHBondContact OD2-NH1 3.38Å
816S82.8Confident80Confident76 Ų7650.1 Ų50.153%0.53127%0.267SS..Hα-helixtrans-57.9-41.9175.7-60.60000112.1L812 N813 Q819 E820L812-S816 WeakPolarHBondContact O-CB 3.44Å; L812-S816 PolarHBondContact O-N 2.69Å; L812-S816 PolarHBondContact O-OG 2.93Å; N813-S816 WeakPolarHBondContact O-CB 3.34Å; N813-S816 PolarHBondContact O-N 3Å; S816-Q819 PolarHBondContact O-N 2.89Å; S816-E820 VanDerWaalsContact O-CB 3.31Å; S816-E820 WeakPolarHBondContact O-CB 3.31Å; S816-E820 PolarHBondContact O-N 2.87Å
817L85.4Confident80.7Confident25 Ų2556.7 Ų56.713%0.13129%0.294CS..Hα-helixtrans-64-44.1176176.162.2000112.4R757 L787 N813 T814 D815 E820 T821R757-L817 HydrophobicContact CB-CD1 4.31Å; R757-L817 HydrophobicContact CB-CD2 4.22Å; R757-L817 VanDerWaalsContact CD-CD1 3.45Å; R757-L817 HydrophobicContact CG-CD1 3.86Å; L787-L817 HydrophobicContact CD1-CD2 4Å; L787-L817 HydrophobicContact CD2-CD2 4.07Å; L787-L817 HydrophobicContact CD2-CG 4.31Å; N813-L817 PolarHBondContact O-N 3.32Å; T814-L817 WeakPolarHBondContact O-CB 3.43Å; T814-L817 PolarHBondContact O-N 3.13Å; D815-L817 VanDerWaalsContact C-N 3.29Å; D815-L817 PolarHBondContact O-N 2.89Å; L817-E820 PolarHBondContact O-N 2.97Å; L817-T821 WeakPolarHBondContact O-CB 3.47Å; L817-T821 PolarHBondContact O-N 3.39Å; L817-T821 PolarHBondContact O-OG1 3.48Å
818I85.6Confident81.4Confident2 Ų262.7 Ų62.71%0.0132%0.321CS..Hα-helixtrans-61.8-47.6177.2-70.8164.6000109.7Q786 L787 T807 V810 T814 D815 T821 I822Q786-I818 HydrophobicContact CB-CD1 4.13Å; Q786-I818 HydrophobicContact CG-CD1 3.75Å; L787-I818 HydrophobicContact CD2-CG1 3.75Å; T807-I818 HydrophobicContact CG2-CG2 4.17Å; V810-I818 HydrophobicContact CG1-CD1 4.16Å; T814-I818 HydrophobicContact CG2-CD1 4.15Å; T814-I818 VanDerWaalsContact O-CG1 3.27Å; T814-I818 WeakPolarHBondContact O-CG1 3.12Å; T814-I818 PolarHBondContact O-N 3.31Å; D815-I818 PolarHBondContact O-N 3.39Å; D815-I818 VanDerWaalsContact O-N 3.15Å; I818-T821 PolarHBondContact O-N 2.98Å; I818-I822 HydrophobicContact CG2-CD1 3.6Å; I818-I822 HydrophobicContact CG2-CG1 4.41Å; I818-I822 VanDerWaalsContact O-CG1 3.25Å; I818-I822 WeakPolarHBondContact O-CG1 3.27Å; I818-I822 PolarHBondContact O-N 3.02Å
819Q83.9Confident82.7Confident28 Ų2862 Ų6213%0.13131%0.314CS..Hα-helixtrans-62.6-42.8178.5-69.6-64.6-18.200112.3D815 S816 I822 R823D815-Q819 WeakPolarHBondContact O-CB 3.42Å; D815-Q819 WeakPolarHBondContact O-CG 3.26Å; D815-Q819 PolarHBondContact O-N 2.82Å; S816-Q819 PolarHBondContact O-N 2.89Å; Q819-I822 PolarHBondContact O-N 3.39Å; Q819-R823 WeakPolarHBondContact O-CB 3.27Å; Q819-R823 VanDerWaalsContact O-CG 3.24Å; Q819-R823 WeakPolarHBondContact O-CG 3.48Å; Q819-R823 PolarHBondContact O-N 2.7Å
820E86.5Confident84.1Confident86 Ų8657.3 Ų57.340%0.40229%0.289SS..Hα-helixtrans-58.5-49.4174.5-172.3-174.7178.700110.8R757 S816 L817 I822 R823 V824R757-E820 IonicContact CZ-OE2 2.75Å; R757-E820 IonicContact NH1-OE2 3.98Å; R757-E820 PolarHBondContact NH1-OE2 3.16Å; R757-E820 IonicContact NH2-OE1 3.36Å; R757-E820 PolarHBondContact NH2-OE1 3.4Å; R757-E820 IonicContact NH2-OE2 3.97Å; R757-E820 PolarHBondContact NH2-OE2 3.21Å; S816-E820 VanDerWaalsContact O-CB 3.31Å; S816-E820 WeakPolarHBondContact O-CB 3.31Å; S816-E820 PolarHBondContact O-N 2.87Å; L817-E820 PolarHBondContact O-N 2.97Å; E820-I822 PolarHBondContact O-N 3.45Å; E820-R823 PolarHBondContact O-N 3.02Å; E820-V824 WeakPolarHBondContact O-CG2 3.47Å; E820-V824 PolarHBondContact O-N 3.24Å
821T88Confident85.2Confident8 Ų857.1 Ų57.15%0.04929%0.288CS..Hα-helixtrans-62.6-42-180-510000111.5V756 L790 L817 I818 R823 V824 E825V756-T821 HydrophobicContact CG1-CG2 4.35Å; L790-T821 HydrophobicContact CD2-CG2 3.68Å; L790-T821 HydrophobicContact CG-CG2 4.37Å; L817-T821 WeakPolarHBondContact O-CB 3.47Å; L817-T821 PolarHBondContact O-N 3.39Å; L817-T821 PolarHBondContact O-OG1 3.48Å; I818-T821 PolarHBondContact O-N 2.98Å; T821-R823 VanDerWaalsContact C-N 3.33Å; T821-R823 PolarHBondContact O-N 3.41Å; T821-V824 PolarHBondContact O-N 3.27Å; T821-E825 HydrophobicContact CG2-CG 4.02Å; T821-E825 WeakPolarHBondContact O-CB 3.4Å; T821-E825 PolarHBondContact O-N 3.29Å
822I87.2Confident86.2Confident8 Ų854.9 Ų54.94%0.04128%0.276CS..Hα-helixtrans-61.4-42.7175.9-69.5163.7000111L790 L803 I818 Q819 E820 F826L790-I822 HydrophobicContact CD1-CG1 4.15Å; L803-I822 HydrophobicContact CD1-CD1 3.78Å; L803-I822 HydrophobicContact CD2-CD1 4.25Å; I818-I822 HydrophobicContact CG2-CD1 3.6Å; I818-I822 HydrophobicContact CG2-CG1 4.41Å; I818-I822 VanDerWaalsContact O-CG1 3.25Å; I818-I822 WeakPolarHBondContact O-CG1 3.27Å; I818-I822 PolarHBondContact O-N 3.02Å; Q819-I822 PolarHBondContact O-N 3.39Å; E820-I822 PolarHBondContact O-N 3.45Å; I822-F826 WeakPolarHBondContact O-CB 3.35Å; I822-F826 PolarHBondContact O-N 3.23Å
823R85.3Confident87.1Confident130 Ų13049.1 Ų49.149%0.49125%0.247SC..Hα-helixtrans-66.3-37.9179.8-73.9171178.6172.24.1112.8Q819 E820 T821 D843Q819-R823 WeakPolarHBondContact O-CB 3.27Å; Q819-R823 VanDerWaalsContact O-CG 3.24Å; Q819-R823 WeakPolarHBondContact O-CG 3.48Å; Q819-R823 PolarHBondContact O-N 2.7Å; E820-R823 PolarHBondContact O-N 3.02Å; T821-R823 VanDerWaalsContact C-N 3.33Å; T821-R823 PolarHBondContact O-N 3.41Å; R823-D843 IonicContact CZ-OD2 3.86Å; R823-D843 IonicContact NE-OD2 3.46Å; R823-D843 PolarHBondContact NE-OD2 3.13Å; R823-D843 VanDerWaalsContact NE-OD2 3.16Å; R823-D843 IonicContact NH2-OD2 3.02Å; R823-D843 PolarHBondContact NH2-OD2 3.01Å
824V87.9Confident87.7Confident92 Ų9242.7 Ų42.756%0.55821%0.212SC*.Hα-helixtrans-80.3-55.5-177.61750000111.2E820 T821E820-V824 WeakPolarHBondContact O-CG2 3.47Å; E820-V824 PolarHBondContact O-N 3.24Å; T821-V824 PolarHBondContact O-N 3.27Å
825E88.3Confident87.5Confident75 Ų7541.9 Ų41.935%0.3521%0.208SC..Hα-helixtrans-82.9-29.8-167.9-62.4-63.7154.200113.3Q755 L794 T821Q755-E825 HydrophobicContact CB-CG 4.45Å; Q755-E825 PolarHBondContact NE2-OE2 3.1Å; L794-E825 HydrophobicContact CD2-CB 3.54Å; L794-E825 HydrophobicContact CD2-CG 4.02Å; T821-E825 HydrophobicContact CG2-CG 4.02Å; T821-E825 WeakPolarHBondContact O-CB 3.4Å; T821-E825 PolarHBondContact O-N 3.29Å
826F88.2Confident87.1Confident8 Ų845.3 Ų45.34%0.03522%0.223CC..THydrogen-bonded Turntrans-104.423.3-176.9-62.4-90.3000113.4L790 A793 L794 L801 I822 H828 C829L790-F826 HydrophobicContact CD1-CE2 3.76Å; L790-F826 HydrophobicContact CD1-CZ 4.32Å; A793-F826 HydrophobicContact CB-CE1 4.41Å; A793-F826 HydrophobicContact CB-CZ 3.96Å; L794-F826 HydrophobicContact CD2-CD2 4.24Å; L794-F826 HydrophobicContact CD2-CE1 4.26Å; L794-F826 HydrophobicContact CD2-CE2 3.43Å; L794-F826 VanDerWaalsContact CD2-CE2 3.43Å; L794-F826 HydrophobicContact CD2-CZ 3.45Å; L794-F826 VanDerWaalsContact CD2-CZ 3.45Å; L794-F826 HydrophobicContact CG-CE2 3.94Å; L794-F826 HydrophobicContact CG-CZ 3.79Å; L801-F826 HydrophobicContact CB-CD1 4.42Å; L801-F826 HydrophobicContact CD1-CE1 4.22Å; L801-F826 HydrophobicContact CD2-CB 4.21Å; L801-F826 HydrophobicContact CD2-CD1 3.69Å; L801-F826 HydrophobicContact CD2-CD2 4.09Å; L801-F826 HydrophobicContact CD2-CE1 3.96Å; L801-F826 HydrophobicContact CD2-CE2 4.33Å; L801-F826 HydrophobicContact CD2-CG 3.73Å; L801-F826 HydrophobicContact CD2-CZ 4.25Å; L801-F826 HydrophobicContact CG-CD1 4.47Å; I822-F826 WeakPolarHBondContact O-CB 3.35Å; I822-F826 PolarHBondContact O-N 3.23Å; F826-H828 PolarHBondContact O-N 2.92Å; F826-H828 VanDerWaalsContact O-N 3.15Å; F826-C829 HydrophobicContact CB-CB 4.32Å; F826-C829 HydrophobicContact CD1-CB 4.42Å; F826-C829 PolarHBondContact O-N 3.39Å; F826-C829 VanDerWaalsContact O-N 3.13Å
827K85.5Confident86.7Confident148 Ų14845.8 Ų45.864%0.64321%0.214SC*.THydrogen-bonded Turntrans-56.1-32-179.3-175.4179.4178.3-177.30113.9
828H86.6Confident86.5Confident134 Ų13445.6 Ų45.662%0.6221%0.213SC*.THydrogen-bonded Turntrans-99.28.4-176.5-60.6-64.1000113.8F826F826-H828 PolarHBondContact O-N 2.92Å; F826-H828 VanDerWaalsContact O-N 3.15Å
829C92.2Very high86.3Confident16 Ų1649.9 Ų49.911%0.10824%0.235CC..SBendtrans-106.6145.6-178.4-58.50000109.8N798 R799 F826N798-C829 PolarHBondContact O-SG 3.5Å; R799-C829 CarbonylContact O-C 3.58Å; R799-C829 VanDerWaalsContact O-CA 3.32Å; R799-C829 WeakPolarHBondContact O-CA 3.36Å; R799-C829 WeakPolarHBondContact O-CB 3.34Å; F826-C829 HydrophobicContact CB-CB 4.32Å; F826-C829 HydrophobicContact CD1-CB 4.42Å; F826-C829 PolarHBondContact O-N 3.39Å; F826-C829 VanDerWaalsContact O-N 3.13Å
830S94.7Very high86.1Confident0 Ų049 Ų490%023%0.232CC..EExtended strand (participates in β ladder)trans-73.9124.7166.7-49.10000108.5G642 K669 P670 G671 E672 R799 I800 L801G642-S830 VanDerWaalsContact O-CB 3.27Å; G642-S830 WeakPolarHBondContact O-CB 3.14Å; G642-S830 PolarHBondContact O-OG 2.82Å; K669-S830 PolarHBondContact O-OG 3.34Å; P670-S830 WeakPolarHBondContact CA-OG 3.38Å; G671-S830 PolarHBondContact N-OG 3.12Å; E672-S830 CarbonylContact O-C 3.54Å; E672-S830 WeakPolarHBondContact O-CA 3.31Å; R799-S830 PolarHBondContact O-N 3.32Å; I800-S830 WeakPolarHBondContact CA-O 3.21Å; L801-S830 PolarHBondContact N-O 3.1Å
831V94.2Very high86.1Confident2 Ų245 Ų451%0.01221%0.213CC..EExtended strand (participates in β ladder)trans-115.6121.2-174.3-172.90000109.9E672 K673 L674 L801 L803E672-V831 PolarHBondContact O-N 3.06Å; K673-V831 CarbonylContact C-O 3.58Å; K673-V831 WeakPolarHBondContact CA-O 3.35Å; K673-V831 HydrophobicContact CG-CB 4.29Å; K673-V831 HydrophobicContact CG-CG2 4.44Å; L674-V831 PolarHBondContact N-O 3.08Å; L801-V831 HydrophobicContact CB-CG2 4.38Å; L801-V831 HydrophobicContact CD2-CG1 4.34Å; L801-V831 HydrophobicContact CD2-CG2 4.45Å; L801-V831 CarbonylContact O-C 3.57Å; L801-V831 WeakPolarHBondContact O-CA 3.3Å; L803-V831 HydrophobicContact CD1-CG1 3.87Å; L803-V831 HydrophobicContact CG-CG1 4.18Å
832L94.6Very high86.1Confident5 Ų544.6 Ų44.63%0.02621%0.211CC..EExtended strand (participates in β ladder)trans-102.5115.6169.717864.9000109.2L674 L691 L801 V802 L803L674-L832 HydrophobicContact CB-CD1 4.32Å; L674-L832 HydrophobicContact CD2-CD1 4.08Å; L674-L832 HydrophobicContact CG-CD1 4.13Å; L674-L832 WeakPolarHBondContact O-CA 3.47Å; L691-L832 HydrophobicContact CD2-CD2 4.24Å; L801-L832 PolarHBondContact O-N 3.25Å; V802-L832 CarbonylContact C-O 3.19Å; V802-L832 WeakPolarHBondContact CA-O 3.47Å; L803-L832 PolarHBondContact N-O 2.85Å
833T92.9Very high86Confident12 Ų1245.5 Ų45.57%0.07422%0.216CC..EExtended strand (participates in β ladder)trans-112.5114.6-176-52.50000110.9L674 G675 L676 L803 A835 I841L674-T833 PolarHBondContact O-N 3.49Å; G675-T833 CarbonylContact C-O 3.54Å; G675-T833 WeakPolarHBondContact CA-O 3.28Å; L676-T833 PolarHBondContact N-O 3.32Å; L803-T833 HydrophobicContact CB-CG2 4.2Å; L803-T833 HydrophobicContact CD1-CG2 4.19Å; T833-A835 HydrophobicContact CG2-CB 4.41Å; T833-I841 HydrophobicContact CG2-CG1 4.24Å
834I89.4Confident86.2Confident1 Ų139.4 Ų39.41%0.00519%0.193CC..EExtended strand (participates in β ladder)trans-91.8122.9164.2-52.6-161.4000107.5L676 K684 I688 L803 E805L676-I834 HydrophobicContact CB-CG1 4.2Å; L676-I834 HydrophobicContact CD2-CD1 3.59Å; L676-I834 HydrophobicContact CD2-CG1 3.82Å; L676-I834 HydrophobicContact CD2-CG2 4.48Å; K684-I834 HydrophobicContact CB-CD1 4.31Å; K684-I834 HydrophobicContact CB-CG2 3.88Å; K684-I834 HydrophobicContact CD-CG2 4.03Å; K684-I834 VanDerWaalsContact O-CD1 3.27Å; K684-I834 WeakPolarHBondContact O-CD1 3.32Å; I688-I834 HydrophobicContact CD1-CD1 3.41Å; I688-I834 VanDerWaalsContact CD1-CD1 3.41Å; I688-I834 HydrophobicContact CD1-CG1 4.07Å; I688-I834 HydrophobicContact CG1-CD1 3.53Å; I688-I834 HydrophobicContact CG1-CG1 4.43Å; L803-I834 PolarHBondContact O-N 2.95Å; E805-I834 WeakPolarHBondContact CA-O 3.3Å; E805-I834 HydrophobicContact CG-CG2 4.18Å; E805-I834 PolarHBondContact N-O 3.15Å
835A76.8Confident86.4Confident8 Ų837 Ų377%0.06618%0.177CC..  trans-139.8148.2175.800000112.4T833 T840 I841T833-A835 HydrophobicContact CG2-CB 4.41Å; A835-T840 WeakPolarHBondContact CB-OG1 3.46Å; A835-I841 HydrophobicContact CB-CD1 3.43Å; A835-I841 VanDerWaalsContact CB-CD1 3.43Å; A835-I841 HydrophobicContact CB-CG1 3.8Å
836H72.3Confident86.6Confident87 Ų8735.2 Ų35.240%0.40317%0.167SC..SBendtrans-87.8-33166.2-168.1-91.3000111.6L838H836-L838 PolarHBondContact O-N 3.4Å
837R74.4Confident86.9Confident87 Ų8734.9 Ų34.933%0.32817%0.165SC..SBendtrans-82.3112.6176.3-64.6-174.9-176.3171.94.3109.5T807 A808 D815 N839 T840T807-R837 PolarHBondContact O-NH1 3.27Å; T807-R837 PolarHBondContact O-NH2 3.04Å; A808-R837 PolarHBondContact O-NH2 2.64Å; D815-R837 IonicContact OD2-NH1 3.04Å; D815-R837 PolarHBondContact OD2-NH1 3.38Å; R837-N839 PolarHBondContact O-N 3.42Å; R837-T840 HydrophobicContact CB-CG2 4.37Å; R837-T840 PolarHBondContact O-N 3Å; R837-T840 PolarHBondContact O-OG1 3.45Å
838L82.4Confident87.3Confident21 Ų2127.8 Ų27.811%0.1114%0.135CC..G310 helixtrans-60.7-30.4-178-65.4177.6000113V677 H836 T840 I841 M842 F872 L875 V876 T879 L887V677-L838 HydrophobicContact CG1-CD2 3.96Å; H836-L838 PolarHBondContact O-N 3.4Å; L838-T840 PolarHBondContact O-N 3.35Å; L838-T840 VanDerWaalsContact O-N 3.16Å; L838-I841 PolarHBondContact O-N 2.9Å; L838-M842 VanDerWaalsContact O-CG 3.28Å; L838-M842 WeakPolarHBondContact O-CG 3.35Å; L838-M842 PolarHBondContact O-N 3.44Å; L838-F872 HydrophobicContact CD2-CE2 4.31Å; L838-L875 HydrophobicContact CD1-CB 4.4Å; L838-L875 WeakPolarHBondContact CD1-O 3.4Å; L838-V876 HydrophobicContact CD1-CB 4.35Å; L838-V876 HydrophobicContact CD1-CG2 3.75Å; L838-T879 HydrophobicContact CD1-CG2 3.75Å; L838-L887 HydrophobicContact CB-CD1 4.11Å
839N81.3Confident87.6Confident92 Ų9221.4 Ų21.449%0.49211%0.105SC..G310 helixtrans-53.6-36.4178.6-167.417.8000113.4R837 I841 L887 I890R837-N839 PolarHBondContact O-N 3.42Å; N839-I841 PolarHBondContact O-N 2.96Å; N839-L887 HydrophobicContact CB-CD2 3.94Å; N839-I890 WeakPolarHBondContact OD1-CD1 3.22Å
840T79.6Confident87.4Confident10 Ų1020.7 Ų20.76%0.06110%0.1CC..G310 helixtrans-76.4-9.1-178.764.10000113.7A835 R837 L838A835-T840 WeakPolarHBondContact CB-OG1 3.46Å; R837-T840 HydrophobicContact CB-CG2 4.37Å; R837-T840 PolarHBondContact O-N 3Å; R837-T840 PolarHBondContact O-OG1 3.45Å; L838-T840 PolarHBondContact O-N 3.35Å; L838-T840 VanDerWaalsContact O-N 3.16Å
841I86.5Confident87.1Confident0 Ų023.7 Ų23.70%011%0.114CC..THydrogen-bonded Turntrans-111.3-15.5-178.3-69.4175.6000111.4V677 T833 A835 L838 N839 D843 C844 V847V677-I841 HydrophobicContact CG1-CD1 3.34Å; V677-I841 HydrophobicContact CG1-CG1 4.49Å; V677-I841 HydrophobicContact CG1-CG2 4.19Å; T833-I841 HydrophobicContact CG2-CG1 4.24Å; A835-I841 HydrophobicContact CB-CD1 3.43Å; A835-I841 VanDerWaalsContact CB-CD1 3.43Å; A835-I841 HydrophobicContact CB-CG1 3.8Å; L838-I841 PolarHBondContact O-N 2.9Å; N839-I841 PolarHBondContact O-N 2.96Å; I841-D843 PolarHBondContact O-N 3.08Å; I841-D843 VanDerWaalsContact O-N 3.15Å; I841-C844 HydrophobicContact CG2-CB 4.37Å; I841-C844 WeakPolarHBondContact O-CB 3.42Å; I841-C844 PolarHBondContact O-N 3.4Å; I841-V847 HydrophobicContact CG2-CB 4.34Å; I841-V847 HydrophobicContact CG2-CG1 3.99Å; I841-V847 HydrophobicContact CG2-CG2 3.42Å; I841-V847 VanDerWaalsContact CG2-CG2 3.42Å
842M87.4Confident86.6Confident0 Ų029.4 Ų29.40%014%0.141CC..THydrogen-bonded Turntrans-61.5-25.6-179.2-62.6-44.7-7200113.7L838 P861 L865 F872 L887 I890 A891L838-M842 VanDerWaalsContact O-CG 3.28Å; L838-M842 WeakPolarHBondContact O-CG 3.35Å; L838-M842 PolarHBondContact O-N 3.44Å; M842-P861 HydrophobicContact CE-CB 4.45Å; M842-L865 HydrophobicContact CE-CD1 3.48Å; M842-L865 VanDerWaalsContact CE-CD1 3.48Å; M842-F872 HydrophobicContact CE-CE1 4.36Å; M842-F872 HydrophobicContact CE-CZ 4.37Å; M842-F872 HydrophobicContact SD-CE1 4.41Å; M842-F872 HydrophobicContact SD-CZ 3.85Å; M842-L887 HydrophobicContact CE-CB 3.94Å; M842-L887 WeakPolarHBondContact CE-O 3.48Å; M842-L887 HydrophobicContact CG-CB 4.12Å; M842-L887 HydrophobicContact CG-CD2 3.5Å; M842-L887 HydrophobicContact CG-CG 4.37Å; M842-L887 HydrophobicContact SD-CB 4.23Å; M842-L887 HydrophobicContact SD-CD2 4.31Å; M842-I890 HydrophobicContact CB-CB 4.15Å; M842-I890 HydrophobicContact CB-CG2 3.64Å; M842-A891 HydrophobicContact CE-CB 3.52Å
843D85.8Confident86Confident27 Ų2729.2 Ų29.214%0.14414%0.14CC..THydrogen-bonded Turntrans-94.18.4177.271.2-23.7000113.7R823 I841 R898R823-D843 IonicContact CZ-OD2 3.86Å; R823-D843 IonicContact NE-OD2 3.46Å; R823-D843 PolarHBondContact NE-OD2 3.13Å; R823-D843 VanDerWaalsContact NE-OD2 3.16Å; R823-D843 IonicContact NH2-OD2 3.02Å; R823-D843 PolarHBondContact NH2-OD2 3.01Å; I841-D843 PolarHBondContact O-N 3.08Å; I841-D843 VanDerWaalsContact O-N 3.15Å; D843-R898 PolarHBondContact O-NH2 3Å
844C88.6Confident85.9Confident2 Ų233.6 Ų33.61%0.01416%0.159CC..SBendtrans-74.8149.9173.8-70.60000112.1K673 I841 V847 R898K673-C844 CarbonylContact O-C 3.6Å; K673-C844 WeakPolarHBondContact O-CB 3.35Å; I841-C844 HydrophobicContact CG2-CB 4.37Å; I841-C844 WeakPolarHBondContact O-CB 3.42Å; I841-C844 PolarHBondContact O-N 3.4Å; C844-V847 HydrophobicContact CB-CG2 4.44Å; C844-R898 VanDerWaalsContact O-CZ 3.28Å; C844-R898 PolarHBondContact O-NH1 3.31Å; C844-R898 PolarHBondContact O-NH2 3.37Å
845D91.9Very high86Confident41 Ų4135.9 Ų35.922%0.21917%0.172CC..SBendtrans-63.1-47.2177.8-64.3-43.3000110.7E672 K673 E860 R898E672-D845 WeakPolarHBondContact CA-OD2 3.24Å; E672-D845 HydrophobicContact CG-CB 3.68Å; K673-D845 PolarHBondContact N-OD2 3.21Å; K673-D845 WeakPolarHBondContact O-CA 3.38Å; K673-D845 WeakPolarHBondContact O-CB 3.3Å; K673-D845 PolarHBondContact O-N 3.36Å; D845-E860 WeakPolarHBondContact O-CG 3.34Å; D845-R898 VanDerWaalsContact CA-CZ 3.49Å; D845-R898 VanDerWaalsContact CA-NH1 3.33Å; D845-R898 PolarHBondContact O-NH1 3.03Å; D845-R898 WeakPolarHBondContact OD1-CD 3.16Å; D845-R898 IonicContact OD1-CZ 2.95Å; D845-R898 IonicContact OD1-NE 3.32Å; D845-R898 PolarHBondContact OD1-NE 3.39Å; D845-R898 IonicContact OD1-NH1 2.75Å; D845-R898 IonicContact OD1-NH2 3.7Å
846R94.1Very high86.7Confident39 Ų3939 Ų3915%0.14719%0.19CC..EExtended strand (participates in β ladder)trans-137.8161172.5-71.7-174.4-69.5174.45.6111.1T667 E672 K673 L674 G675 Y858 D859 E860T667-R846 PolarHBondContact O-NH2 2.96Å; E672-R846 IonicContact OE1-CZ 3.51Å; E672-R846 IonicContact OE1-NE 2.72Å; E672-R846 PolarHBondContact OE1-NE 3.34Å; E672-R846 IonicContact OE1-NH2 2.89Å; E672-R846 PolarHBondContact OE1-NH2 3.45Å; E672-R846 IonicContact OE2-CZ 2.79Å; E672-R846 IonicContact OE2-NE 2.81Å; E672-R846 IonicContact OE2-NH2 3.16Å; E672-R846 PolarHBondContact OE2-NH2 3.41Å; K673-R846 PolarHBondContact O-N 3.34Å; L674-R846 WeakPolarHBondContact CA-O 3.26Å; L674-R846 HydrophobicContact CD1-CB 3.87Å; G675-R846 PolarHBondContact N-O 2.88Å; R846-Y858 HydrophobicContact CB-CE2 4.08Å; R846-Y858 VanDerWaalsContact NH1-CZ 3.29Å; R846-Y858 PolarHBondContact NH1-OH 3.5Å; R846-Y858 PolarHBondContact NH2-OH 2.92Å; R846-D859 CarbonylContact C-O 3.55Å; R846-D859 WeakPolarHBondContact CA-O 3.36Å; R846-E860 HydrophobicContact CG-CG 4.42Å
847V93.9Very high87.6Confident0 Ų036.1 Ų36.10%018%0.176CC..EExtended strand (participates in β ladder)trans-129138.1177.3-178.20000109.5G675 V677 I841 C844 Y858 D859 P861 L864 F872G675-V847 CarbonylContact O-C 3.6Å; G675-V847 VanDerWaalsContact O-CA 3.32Å; G675-V847 WeakPolarHBondContact O-CA 3.3Å; V677-V847 HydrophobicContact CG1-CG1 4.26Å; V677-V847 HydrophobicContact CG2-CG1 3.67Å; I841-V847 HydrophobicContact CG2-CB 4.34Å; I841-V847 HydrophobicContact CG2-CG1 3.99Å; I841-V847 HydrophobicContact CG2-CG2 3.42Å; I841-V847 VanDerWaalsContact CG2-CG2 3.42Å; C844-V847 HydrophobicContact CB-CG2 4.44Å; V847-Y858 WeakPolarHBondContact O-CA 3.22Å; V847-D859 PolarHBondContact N-O 2.83Å; V847-D859 PolarHBondContact O-N 3.23Å; V847-P861 HydrophobicContact CG2-CB 4.26Å; V847-P861 HydrophobicContact CG2-CG 3.71Å; V847-L864 HydrophobicContact CB-CD1 4.32Å; V847-F872 HydrophobicContact CG1-CD2 4.18Å; V847-F872 HydrophobicContact CG1-CE2 3.91Å
848I93.2Very high88.5Confident0 Ų035 Ų350%017%0.173CC..EExtended strand (participates in β ladder)trans-105.8129.7171.3-69.1169000108.4F666 L674 G675 L676 V677 L850 L855 E857 Y858F666-I848 HydrophobicContact CB-CD1 3.76Å; F666-I848 HydrophobicContact CD1-CD1 3.86Å; F666-I848 HydrophobicContact CD2-CD1 3.54Å; F666-I848 HydrophobicContact CE1-CD1 4.33Å; F666-I848 HydrophobicContact CE2-CD1 4.05Å; F666-I848 HydrophobicContact CG-CD1 3.44Å; F666-I848 VanDerWaalsContact CG-CD1 3.44Å; F666-I848 HydrophobicContact CZ-CD1 4.41Å; L674-I848 HydrophobicContact CD1-CD1 4Å; L674-I848 HydrophobicContact CD1-CG1 4.01Å; L674-I848 HydrophobicContact CD2-CD1 3.76Å; L674-I848 HydrophobicContact CG-CD1 4.09Å; G675-I848 PolarHBondContact O-N 2.87Å; L676-I848 HydrophobicContact CD1-CB 3.99Å; L676-I848 HydrophobicContact CD1-CD1 4.45Å; L676-I848 HydrophobicContact CD1-CG2 3.73Å; V677-I848 WeakPolarHBondContact CG2-O 3.45Å; V677-I848 PolarHBondContact N-O 3.29Å; I848-L850 HydrophobicContact CG2-CD2 4.35Å; I848-L850 HydrophobicContact CG2-CG 4.3Å; I848-L855 HydrophobicContact CD1-CD1 4.25Å; I848-L855 HydrophobicContact CG1-CD1 4.17Å; I848-L855 HydrophobicContact CG2-CD1 3.64Å; I848-L855 HydrophobicContact CG2-CG 3.9Å; I848-E857 WeakPolarHBondContact CA-O 2.98Å; I848-Y858 HydrophobicContact CD1-CD2 4.28Å; I848-Y858 HydrophobicContact CD1-CE2 4.3Å; I848-Y858 HydrophobicContact CG1-CD2 3.49Å; I848-Y858 VanDerWaalsContact CG1-CD2 3.49Å; I848-Y858 HydrophobicContact CG1-CE2 3.94Å; I848-Y858 HydrophobicContact CG1-CG 4.22Å
849V92.5Very high89Confident0 Ų036.1 Ų36.10%018%0.179CC..EExtended strand (participates in β ladder)trans-104.1118.2170.9-1730000109.3V677 V856 E857 M871 F872 L875V677-V849 HydrophobicContact CG2-CB 4.34Å; V677-V849 HydrophobicContact CG2-CG1 4.49Å; V677-V849 HydrophobicContact CG2-CG2 3.76Å; V677-V849 WeakPolarHBondContact O-CA 3.27Å; V849-V856 PolarHBondContact O-N 3.46Å; V849-E857 HydrophobicContact CB-CB 3.97Å; V849-E857 HydrophobicContact CB-CG 4.35Å; V849-E857 HydrophobicContact CG2-CB 3.88Å; V849-E857 HydrophobicContact CG2-CG 4.41Å; V849-E857 WeakPolarHBondContact CG2-OE2 3.37Å; V849-E857 PolarHBondContact N-O 2.77Å; V849-M871 HydrophobicContact CG1-CB 4.28Å; V849-M871 HydrophobicContact CG1-CG 4.12Å; V849-M871 HydrophobicContact CG1-SD 3.92Å; V849-F872 HydrophobicContact CG2-CB 3.85Å; V849-F872 HydrophobicContact CG2-CD2 4.16Å; V849-F872 HydrophobicContact CG2-CG 4.42Å; V849-L875 HydrophobicContact CG1-CD1 4.35Å
850L89.8Confident89.5Confident1 Ų134 Ų341%0.00517%0.166CC..EExtended strand (participates in β ladder)trans-96.4134172.5-70.7178.2000111.2L676 V677 G678 A682 V687 I848 Q854 L855L676-L850 HydrophobicContact CD1-CD1 3.87Å; L676-L850 HydrophobicContact CD1-CG 4.13Å; L676-L850 HydrophobicContact CD2-CD1 3.91Å; L676-L850 HydrophobicContact CG-CD1 4.09Å; L676-L850 HydrophobicContact CG-CG 4.49Å; V677-L850 PolarHBondContact O-N 3.46Å; G678-L850 WeakPolarHBondContact CA-O 3.4Å; A682-L850 HydrophobicContact CB-CB 4.23Å; A682-L850 WeakPolarHBondContact CB-O 3.43Å; V687-L850 HydrophobicContact CG2-CD1 3.83Å; I848-L850 HydrophobicContact CG2-CD2 4.35Å; I848-L850 HydrophobicContact CG2-CG 4.3Å; L850-Q854 WeakPolarHBondContact CA-O 3.49Å; L850-Q854 WeakPolarHBondContact CD2-O 3.47Å; L850-L855 HydrophobicContact CD2-CB 4.26Å
851H87.3Confident90.1Very high62 Ų6233.7 Ų33.729%0.28716%0.164SC..EExtended strand (participates in β ladder)trans-137126.8172-164.878.7000109.6G853 Q854 V856 M871H851-G853 PolarHBondContact O-N 3.43Å; H851-Q854 PolarHBondContact N-O 3.42Å; H851-Q854 PolarHBondContact O-N 3.4Å; H851-V856 HydrophobicContact CB-CG2 3.47Å; H851-V856 VanDerWaalsContact CB-CG2 3.47Å; H851-M871 HydrophobicContact CB-CE 3.99Å; H851-M871 HydrophobicContact CB-SD 3.81Å; H851-M871 PolarHBondContact ND1-SD 3.12Å
852E83.6Confident90.3Very high123 Ų12333.8 Ų33.858%0.57517%0.165SC*.THydrogen-bonded Turntrans48.137.3178.6-60.6-168.4161.900114.6Q854E852-Q854 VanDerWaalsContact C-N 3.31Å; E852-Q854 PolarHBondContact O-N 3.49Å
853G82.3Confident90.5Very high1 Ų136.3 Ų36.31%0.0118%0.178CC..THydrogen-bonded Turntrans81.82.217900000115.8I660 L661 R662 V664 A682 H851I660-G853 WeakPolarHBondContact O-CA 3.24Å; L661-G853 WeakPolarHBondContact CA-O 3.15Å; R662-G853 PolarHBondContact N-O 3.03Å; V664-G853 WeakPolarHBondContact CG2-O 3.49Å; A682-G853 PolarHBondContact O-N 3.12Å; H851-G853 PolarHBondContact O-N 3.43Å
854Q90.8Very high90.7Very high103 Ų10335 Ų3548%0.48117%0.171SC..EExtended strand (participates in β ladder)trans-110.6150176.3-66.1-177.1-7.200111R662 L850 H851 E852R662-Q854 HydrophobicContact CB-CG 4.01Å; L850-Q854 WeakPolarHBondContact CA-O 3.49Å; L850-Q854 WeakPolarHBondContact CD2-O 3.47Å; H851-Q854 PolarHBondContact N-O 3.42Å; H851-Q854 PolarHBondContact O-N 3.4Å; E852-Q854 VanDerWaalsContact C-N 3.31Å; E852-Q854 PolarHBondContact O-N 3.49Å
855L91.7Very high90.7Very high50 Ų5035.9 Ų35.926%0.26218%0.175SC..EExtended strand (participates in β ladder)trans-82.9116.4170.6-178.7154.3000108.6V664 F666 I848 L850V664-L855 HydrophobicContact CG1-CB 4.49Å; F666-L855 HydrophobicContact CB-CD1 3.99Å; F666-L855 HydrophobicContact CD1-CD1 4.34Å; I848-L855 HydrophobicContact CD1-CD1 4.25Å; I848-L855 HydrophobicContact CG1-CD1 4.17Å; I848-L855 HydrophobicContact CG2-CD1 3.64Å; I848-L855 HydrophobicContact CG2-CG 3.9Å; L850-L855 HydrophobicContact CD2-CB 4.26Å
856V91.1Very high90.5Very high73 Ų7341.8 Ų41.844%0.44220%0.195SC..EExtended strand (participates in β ladder)trans-98.4-41.6-177.1-1760000111.2V849 H851V849-V856 PolarHBondContact O-N 3.46Å; H851-V856 HydrophobicContact CB-CG2 3.47Å; H851-V856 VanDerWaalsContact CB-CG2 3.47Å
857E91.8Very high90.2Very high26 Ų2646.6 Ų46.612%0.12121%0.213CC..EExtended strand (participates in β ladder)trans-135.6146-176.9-51.6-174134.500111I848 V849 L864 S870 M871 F872I848-E857 WeakPolarHBondContact CA-O 2.98Å; V849-E857 HydrophobicContact CB-CB 3.97Å; V849-E857 HydrophobicContact CB-CG 4.35Å; V849-E857 HydrophobicContact CG2-CB 3.88Å; V849-E857 HydrophobicContact CG2-CG 4.41Å; V849-E857 WeakPolarHBondContact CG2-OE2 3.37Å; V849-E857 PolarHBondContact N-O 2.77Å; E857-L864 HydrophobicContact CB-CD2 4.06Å; E857-S870 WeakPolarHBondContact OE1-CA 2.74Å; E857-S870 WeakPolarHBondContact OE1-CB 3.42Å; E857-S870 PolarHBondContact OE1-OG 3.47Å; E857-S870 PolarHBondContact OE2-OG 3.14Å; E857-M871 PolarHBondContact OE1-N 2.9Å; E857-M871 PolarHBondContact OE2-N 3.42Å; E857-F872 WeakPolarHBondContact OE2-CB 3.5Å; E857-F872 PolarHBondContact OE2-N 3.41Å
858Y92.8Very high89.2Confident64 Ų6452.8 Ų52.825%0.25126%0.256SS..EExtended strand (participates in β ladder)trans-156.397.3-180175-139.7000111F666 T667 L674 R846 V847 I848F666-Y858 HydrophobicContact CB-CE1 4.39Å; T667-Y858 PolarHBondContact O-OH 3.48Å; L674-Y858 HydrophobicContact CD1-CD2 4.46Å; L674-Y858 HydrophobicContact CD1-CE2 3.81Å; R846-Y858 HydrophobicContact CB-CE2 4.08Å; R846-Y858 VanDerWaalsContact NH1-CZ 3.29Å; R846-Y858 PolarHBondContact NH1-OH 3.5Å; R846-Y858 PolarHBondContact NH2-OH 2.92Å; V847-Y858 WeakPolarHBondContact O-CA 3.22Å; I848-Y858 HydrophobicContact CD1-CD2 4.28Å; I848-Y858 HydrophobicContact CD1-CE2 4.3Å; I848-Y858 HydrophobicContact CG1-CD2 3.49Å; I848-Y858 VanDerWaalsContact CG1-CD2 3.49Å; I848-Y858 HydrophobicContact CG1-CE2 3.94Å; I848-Y858 HydrophobicContact CG1-CG 4.22Å
859D92.2Very high88.7Confident45 Ų4558.1 Ų58.124%0.24129%0.293CS..EExtended strand (participates in β ladder)trans-164.5-177.2179.3-144.9-27000112R846 V847 L864R846-D859 CarbonylContact C-O 3.55Å; R846-D859 WeakPolarHBondContact CA-O 3.36Å; V847-D859 PolarHBondContact N-O 2.83Å; V847-D859 PolarHBondContact O-N 3.23Å; D859-L864 HydrophobicContact CB-CD2 3.71Å; D859-L864 HydrophobicContact CB-CG 3.94Å
860E92.2Very high88.4Confident46 Ų4658.2 Ų58.222%0.21529%0.294CS..  trans-64.4139.7171.5-55.7-169.9-174.600111.1D845 R846 A862 I863 L864 M895D845-E860 WeakPolarHBondContact O-CG 3.34Å; R846-E860 HydrophobicContact CG-CG 4.42Å; E860-A862 VanDerWaalsContact C-N 3.29Å; E860-A862 PolarHBondContact O-N 3.3Å; E860-A862 VanDerWaalsContact O-N 3.15Å; E860-I863 HydrophobicContact CB-CD1 4.07Å; E860-I863 HydrophobicContact CB-CG1 4.14Å; E860-I863 HydrophobicContact CG-CD1 4.21Å; E860-I863 PolarHBondContact O-N 3.43Å; E860-L864 PolarHBondContact O-N 3.49Å; E860-L864 VanDerWaalsContact O-N 3.15Å; E860-M895 HydrophobicContact CB-CE 4.06Å; E860-M895 WeakPolarHBondContact OE2-CE 3.21Å
861P92.1Very high88.2Confident4 Ų460.2 Ų60.23%0.02630%0.304CS..Hα-helixtrans-53-41.8-176.1-14.212.7000114.1M842 V847 I863 L864 L865 F872 A891M842-P861 HydrophobicContact CE-CB 4.45Å; V847-P861 HydrophobicContact CG2-CB 4.26Å; V847-P861 HydrophobicContact CG2-CG 3.71Å; P861-I863 VanDerWaalsContact C-N 3.32Å; P861-I863 PolarHBondContact O-N 3.03Å; P861-L864 PolarHBondContact O-N 3.04Å; P861-L865 WeakPolarHBondContact O-CB 3.33Å; P861-L865 VanDerWaalsContact O-CG 3.31Å; P861-L865 WeakPolarHBondContact O-CG 3.42Å; P861-L865 PolarHBondContact O-N 2.94Å; P861-F872 HydrophobicContact CB-CE1 4.08Å; P861-F872 HydrophobicContact CB-CZ 4.35Å; P861-A891 HydrophobicContact CB-CB 3.94Å
862A90.9Very high88.2Confident3 Ų357.2 Ų57.23%0.02529%0.29CS..Hα-helixtrans-70.6-24.6-179.900000113.5E860 R866 A891 E892 M895E860-A862 VanDerWaalsContact C-N 3.29Å; E860-A862 PolarHBondContact O-N 3.3Å; E860-A862 VanDerWaalsContact O-N 3.15Å; A862-R866 WeakPolarHBondContact O-CD 3.35Å; A862-R866 VanDerWaalsContact O-CG 3.3Å; A862-R866 WeakPolarHBondContact O-CG 3.34Å; A862-R866 PolarHBondContact O-N 3.18Å; A862-A891 HydrophobicContact CB-CB 4.14Å; A862-E892 HydrophobicContact CB-CG 4.33Å; A862-M895 HydrophobicContact CB-CB 4.32Å; A862-M895 HydrophobicContact CB-CE 3.57Å; A862-M895 HydrophobicContact CB-SD 4.09Å
863I91.1Very high88.4Confident52 Ų5252 Ų5227%0.26727%0.268SS..Hα-helixtrans-74.9-44.5173.7-60.7177.4000109.7E860 P861 L865 R866 R867 M895E860-I863 HydrophobicContact CB-CD1 4.07Å; E860-I863 HydrophobicContact CB-CG1 4.14Å; E860-I863 HydrophobicContact CG-CD1 4.21Å; E860-I863 PolarHBondContact O-N 3.43Å; P861-I863 VanDerWaalsContact C-N 3.32Å; P861-I863 PolarHBondContact O-N 3.03Å; I863-L865 VanDerWaalsContact C-N 3.33Å; I863-L865 PolarHBondContact O-N 3.34Å; I863-R866 PolarHBondContact O-N 2.92Å; I863-R867 PolarHBondContact O-N 3.5Å; I863-M895 HydrophobicContact CD1-CE 4.12Å; I863-M895 HydrophobicContact CG1-CE 3.51Å
864L90.6Very high88.5Confident1 Ų157.3 Ų57.31%0.00529%0.292CS..Hα-helixtrans-60.6-43176.9-63.4179.8000111.2V847 E857 D859 E860 P861 R866 R867 S870 F872V847-L864 HydrophobicContact CB-CD1 4.32Å; E857-L864 HydrophobicContact CB-CD2 4.06Å; D859-L864 HydrophobicContact CB-CD2 3.71Å; D859-L864 HydrophobicContact CB-CG 3.94Å; E860-L864 PolarHBondContact O-N 3.49Å; E860-L864 VanDerWaalsContact O-N 3.15Å; P861-L864 PolarHBondContact O-N 3.04Å; L864-R866 VanDerWaalsContact C-N 3.27Å; L864-R866 PolarHBondContact O-N 2.67Å; L864-R867 WeakPolarHBondContact O-CB 3.24Å; L864-R867 PolarHBondContact O-N 3.42Å; L864-R867 VanDerWaalsContact O-N 3.1Å; L864-S870 WeakPolarHBondContact O-CB 3.42Å; L864-S870 PolarHBondContact O-OG 3.42Å; L864-F872 HydrophobicContact CB-CB 4.04Å; L864-F872 HydrophobicContact CB-CD1 3.7Å; L864-F872 HydrophobicContact CB-CG 4.19Å; L864-F872 HydrophobicContact CD1-CB 4.14Å; L864-F872 HydrophobicContact CD1-CD1 4.22Å; L864-F872 HydrophobicContact CD1-CG 4.15Å
865L89.8Confident88.2Confident19 Ų1953.6 Ų53.610%0.09928%0.276CS..Hα-helixtrans-66.2-23.4179.2-75.1168.3000115M842 P861 I863 R867 F872 A873 V876 R888 A891M842-L865 HydrophobicContact CE-CD1 3.48Å; M842-L865 VanDerWaalsContact CE-CD1 3.48Å; P861-L865 WeakPolarHBondContact O-CB 3.33Å; P861-L865 VanDerWaalsContact O-CG 3.31Å; P861-L865 WeakPolarHBondContact O-CG 3.42Å; P861-L865 PolarHBondContact O-N 2.94Å; I863-L865 VanDerWaalsContact C-N 3.33Å; I863-L865 PolarHBondContact O-N 3.34Å; L865-R867 VanDerWaalsContact C-N 3.34Å; L865-F872 HydrophobicContact CD1-CE1 4.14Å; L865-F872 HydrophobicContact CD2-CD1 4.07Å; L865-F872 HydrophobicContact CD2-CE1 4.13Å; L865-F872 HydrophobicContact CG-CD1 3.95Å; L865-F872 HydrophobicContact CG-CE1 3.83Å; L865-A873 HydrophobicContact CD2-CB 4.34Å; L865-V876 HydrophobicContact CD2-CB 3.85Å; L865-V876 HydrophobicContact CD2-CG1 3.99Å; L865-V876 HydrophobicContact CD2-CG2 3.73Å; L865-R888 HydrophobicContact CD1-CG 3.98Å; L865-R888 HydrophobicContact CD2-CG 4.4Å; L865-A891 HydrophobicContact CD1-CB 4.03Å
866R87.8Confident87.9Confident166 Ų16651.3 Ų51.363%0.62626%0.264SS*.Hα-helixtrans-79.2-20.3175.6-73.9172-175.4-170.20.5112.7A862 I863 L864 S868 E892A862-R866 WeakPolarHBondContact O-CD 3.35Å; A862-R866 VanDerWaalsContact O-CG 3.3Å; A862-R866 WeakPolarHBondContact O-CG 3.34Å; A862-R866 PolarHBondContact O-N 3.18Å; I863-R866 PolarHBondContact O-N 2.92Å; L864-R866 VanDerWaalsContact C-N 3.27Å; L864-R866 PolarHBondContact O-N 2.67Å; R866-S868 PolarHBondContact O-N 3.14Å; R866-E892 IonicContact NE-OE1 3.09Å; R866-E892 IonicContact NH2-OE1 3.42Å; R866-E892 PolarHBondContact NH2-OE1 3.32Å
867R87.4Confident87.5Confident140 Ų14051 Ų5153%0.52827%0.265SS..  trans-82.5111.9177.6-73.8176.8154.3170.2-3.1108.8I863 L864 L865 S869 S870I863-R867 PolarHBondContact O-N 3.5Å; L864-R867 WeakPolarHBondContact O-CB 3.24Å; L864-R867 PolarHBondContact O-N 3.42Å; L864-R867 VanDerWaalsContact O-N 3.1Å; L865-R867 VanDerWaalsContact C-N 3.34Å; R867-S869 PolarHBondContact O-N 3.4Å; R867-S870 WeakPolarHBondContact O-CB 3.42Å; R867-S870 PolarHBondContact O-N 3.42Å; R867-S870 VanDerWaalsContact O-N 3.07Å
868S72.9Confident86.9Confident129 Ų12952.5 Ų52.590%0.90227%0.272SS*.THydrogen-bonded Turntrans-62.4-25.5179.255.20000113.7R866 S870R866-S868 PolarHBondContact O-N 3.14Å; S868-S870 VanDerWaalsContact C-N 3.3Å
869S82.6Confident86Confident112 Ų11251.3 Ų51.378%0.78327%0.272SS*.THydrogen-bonded Turntrans-88.99.3177.467.30000113.7R867R867-S869 PolarHBondContact O-N 3.4Å
870S84.7Confident85.3Confident3 Ų350.8 Ų50.82%0.02128%0.277CS..  trans-82.2131.2-172.6174.60000112.1E857 L864 R867 S868 F872 A873 E874E857-S870 WeakPolarHBondContact OE1-CA 2.74Å; E857-S870 WeakPolarHBondContact OE1-CB 3.42Å; E857-S870 PolarHBondContact OE1-OG 3.47Å; E857-S870 PolarHBondContact OE2-OG 3.14Å; L864-S870 WeakPolarHBondContact O-CB 3.42Å; L864-S870 PolarHBondContact O-OG 3.42Å; R867-S870 WeakPolarHBondContact O-CB 3.42Å; R867-S870 PolarHBondContact O-N 3.42Å; R867-S870 VanDerWaalsContact O-N 3.07Å; S868-S870 VanDerWaalsContact C-N 3.3Å; S870-F872 PolarHBondContact O-N 3.42Å; S870-F872 WeakPolarHBondContact OG-CB 3.47Å; S870-F872 PolarHBondContact OG-N 2.89Å; S870-A873 WeakPolarHBondContact O-CB 3.36Å; S870-A873 PolarHBondContact O-N 3.12Å; S870-A873 VanDerWaalsContact O-N 3.09Å; S870-A873 PolarHBondContact OG-N 3.14Å; S870-E874 PolarHBondContact O-N 3.24Å
871M85.5Confident84.6Confident42 Ų4253.6 Ų53.621%0.20730%0.301CS..Hα-helixtrans-65.3-32.4174.3-173.2178.7-68.800110.9V849 H851 E857 A873 E874 L875V849-M871 HydrophobicContact CG1-CB 4.28Å; V849-M871 HydrophobicContact CG1-CG 4.12Å; V849-M871 HydrophobicContact CG1-SD 3.92Å; H851-M871 HydrophobicContact CB-CE 3.99Å; H851-M871 HydrophobicContact CB-SD 3.81Å; H851-M871 PolarHBondContact ND1-SD 3.12Å; E857-M871 PolarHBondContact OE1-N 2.9Å; E857-M871 PolarHBondContact OE2-N 3.42Å; M871-A873 VanDerWaalsContact C-N 3.35Å; M871-E874 WeakPolarHBondContact O-CB 3.44Å; M871-E874 PolarHBondContact O-N 2.96Å; M871-L875 WeakPolarHBondContact O-CG 3.11Å; M871-L875 PolarHBondContact O-N 3.09Å
872F88.6Confident84Confident0 Ų061.2 Ų61.20%034%0.336CS..Hα-helixtrans-60.6-43.1169.9-171.5-113.6000112.5V677 L838 M842 V847 V849 E857 P861 L864 L865 S870 E874 L875 V876V677-F872 HydrophobicContact CG2-CD2 3.87Å; V677-F872 HydrophobicContact CG2-CE2 4.09Å; L838-F872 HydrophobicContact CD2-CE2 4.31Å; M842-F872 HydrophobicContact CE-CE1 4.36Å; M842-F872 HydrophobicContact CE-CZ 4.37Å; M842-F872 HydrophobicContact SD-CE1 4.41Å; M842-F872 HydrophobicContact SD-CZ 3.85Å; V847-F872 HydrophobicContact CG1-CD2 4.18Å; V847-F872 HydrophobicContact CG1-CE2 3.91Å; V849-F872 HydrophobicContact CG2-CB 3.85Å; V849-F872 HydrophobicContact CG2-CD2 4.16Å; V849-F872 HydrophobicContact CG2-CG 4.42Å; E857-F872 WeakPolarHBondContact OE2-CB 3.5Å; E857-F872 PolarHBondContact OE2-N 3.41Å; P861-F872 HydrophobicContact CB-CE1 4.08Å; P861-F872 HydrophobicContact CB-CZ 4.35Å; L864-F872 HydrophobicContact CB-CB 4.04Å; L864-F872 HydrophobicContact CB-CD1 3.7Å; L864-F872 HydrophobicContact CB-CG 4.19Å; L864-F872 HydrophobicContact CD1-CB 4.14Å; L864-F872 HydrophobicContact CD1-CD1 4.22Å; L864-F872 HydrophobicContact CD1-CG 4.15Å; L865-F872 HydrophobicContact CD1-CE1 4.14Å; L865-F872 HydrophobicContact CD2-CD1 4.07Å; L865-F872 HydrophobicContact CD2-CE1 4.13Å; L865-F872 HydrophobicContact CG-CD1 3.95Å; L865-F872 HydrophobicContact CG-CE1 3.83Å; S870-F872 PolarHBondContact O-N 3.42Å; S870-F872 WeakPolarHBondContact OG-CB 3.47Å; S870-F872 PolarHBondContact OG-N 2.89Å; F872-E874 VanDerWaalsContact C-N 3.31Å; F872-E874 PolarHBondContact O-N 3.08Å; F872-L875 PolarHBondContact O-N 2.7Å; F872-V876 HydrophobicContact CD1-CG2 4.46Å; F872-V876 HydrophobicContact CE1-CG2 4.15Å; F872-V876 HydrophobicContact CZ-CG2 4.21Å; F872-V876 WeakPolarHBondContact O-CG2 3.41Å; F872-V876 PolarHBondContact O-N 2.98Å
873A86.8Confident83.3Confident14 Ų1464.8 Ų64.812%0.11636%0.355CS..Hα-helixtrans-65.6-36.6177.700000111.8L865 S870 M871 V876 S877L865-A873 HydrophobicContact CD2-CB 4.34Å; S870-A873 WeakPolarHBondContact O-CB 3.36Å; S870-A873 PolarHBondContact O-N 3.12Å; S870-A873 VanDerWaalsContact O-N 3.09Å; S870-A873 PolarHBondContact OG-N 3.14Å; M871-A873 VanDerWaalsContact C-N 3.35Å; A873-V876 PolarHBondContact O-N 2.95Å; A873-S877 WeakPolarHBondContact O-CB 3.4Å; A873-S877 PolarHBondContact O-N 3.5Å
874E85.4Confident82.9Confident111 Ų11162.6 Ų62.652%0.51935%0.345SS..Hα-helixtrans-61.7-51.3172.2-171.2178.4-171.600111S870 M871 F872 V876 S877 E878S870-E874 PolarHBondContact O-N 3.24Å; M871-E874 WeakPolarHBondContact O-CB 3.44Å; M871-E874 PolarHBondContact O-N 2.96Å; F872-E874 VanDerWaalsContact C-N 3.31Å; F872-E874 PolarHBondContact O-N 3.08Å; E874-V876 VanDerWaalsContact C-N 3.26Å; E874-V876 PolarHBondContact O-N 3.25Å; E874-S877 WeakPolarHBondContact CA-OG 3.46Å; E874-S877 WeakPolarHBondContact O-CA 3.41Å; E874-S877 WeakPolarHBondContact O-CB 3.04Å; E874-S877 PolarHBondContact O-N 2.92Å; E874-S877 PolarHBondContact O-OG 2.77Å; E874-E878 WeakPolarHBondContact O-CG 2.83Å; E874-E878 PolarHBondContact O-N 3.49Å
875L83.6Confident82.7Confident26 Ų2666.2 Ų66.214%0.13636%0.362CS..Hα-helixtrans-56.9-38.2176.1-71.5171.5000112.6V677 R679 L838 V849 M871 F872V677-L875 HydrophobicContact CG2-CD1 4.45Å; R679-L875 HydrophobicContact CG-CD2 4.31Å; L838-L875 HydrophobicContact CD1-CB 4.4Å; L838-L875 WeakPolarHBondContact CD1-O 3.4Å; V849-L875 HydrophobicContact CG1-CD1 4.35Å; M871-L875 WeakPolarHBondContact O-CG 3.11Å; M871-L875 PolarHBondContact O-N 3.09Å; F872-L875 PolarHBondContact O-N 2.7Å
876V85.9Confident82.5Confident1 Ų168.8 Ų68.81%0.00638%0.378CS..Hα-helixtrans-69-40.6175.1172.30000110.9L838 L865 F872 A873 E874 E878 T879 A884 L887L838-V876 HydrophobicContact CD1-CB 4.35Å; L838-V876 HydrophobicContact CD1-CG2 3.75Å; L865-V876 HydrophobicContact CD2-CB 3.85Å; L865-V876 HydrophobicContact CD2-CG1 3.99Å; L865-V876 HydrophobicContact CD2-CG2 3.73Å; F872-V876 HydrophobicContact CD1-CG2 4.46Å; F872-V876 HydrophobicContact CE1-CG2 4.15Å; F872-V876 HydrophobicContact CZ-CG2 4.21Å; F872-V876 WeakPolarHBondContact O-CG2 3.41Å; F872-V876 PolarHBondContact O-N 2.98Å; A873-V876 PolarHBondContact O-N 2.95Å; E874-V876 VanDerWaalsContact C-N 3.26Å; E874-V876 PolarHBondContact O-N 3.25Å; V876-E878 VanDerWaalsContact C-N 3.26Å; V876-E878 PolarHBondContact O-N 2.75Å; V876-T879 WeakPolarHBondContact O-CB 3.49Å; V876-T879 PolarHBondContact O-N 3.4Å; V876-T879 VanDerWaalsContact O-N 3.09Å; V876-T879 PolarHBondContact O-OG1 3.01Å; V876-A884 HydrophobicContact CG1-CB 3.8Å; V876-L887 HydrophobicContact CG1-CB 4.26Å; V876-L887 HydrophobicContact CG1-CD1 4.09Å
877S83.1Confident82.5Confident68 Ų6861.5 Ų61.548%0.47635%0.351SS..Hα-helixtrans-64.8-30.3177.874.60000113.3A873 E874 T879 G880A873-S877 WeakPolarHBondContact O-CB 3.4Å; A873-S877 PolarHBondContact O-N 3.5Å; E874-S877 WeakPolarHBondContact CA-OG 3.46Å; E874-S877 WeakPolarHBondContact O-CA 3.41Å; E874-S877 WeakPolarHBondContact O-CB 3.04Å; E874-S877 PolarHBondContact O-N 2.92Å; E874-S877 PolarHBondContact O-OG 2.77Å; S877-T879 PolarHBondContact O-N 3.17Å; S877-G880 PolarHBondContact O-N 3.38Å
878E78.3Confident82.6Confident57 Ų5759.8 Ų59.827%0.26635%0.345SS..THydrogen-bonded Turntrans-65.1-15.5174.2-70.4-179.3164.600113.1T303 E874 V876 G880T303-E878 WeakPolarHBondContact CB-O 3.47Å; T303-E878 WeakPolarHBondContact CG2-O 3.35Å; E874-E878 WeakPolarHBondContact O-CG 2.83Å; E874-E878 PolarHBondContact O-N 3.49Å; V876-E878 VanDerWaalsContact C-N 3.26Å; V876-E878 PolarHBondContact O-N 2.75Å; E878-G880 VanDerWaalsContact C-N 3.26Å; E878-G880 PolarHBondContact O-N 3.29Å
879T74.5Confident83.4Confident39 Ų3960.4 Ų60.424%0.23933%0.328CS..THydrogen-bonded Turntrans-79.9-3.9176.4680000114.3L838 V876 S877 N883 L887L838-T879 HydrophobicContact CD1-CG2 3.75Å; V876-T879 WeakPolarHBondContact O-CB 3.49Å; V876-T879 PolarHBondContact O-N 3.4Å; V876-T879 VanDerWaalsContact O-N 3.09Å; V876-T879 PolarHBondContact O-OG1 3.01Å; S877-T879 PolarHBondContact O-N 3.17Å; T879-N883 PolarHBondContact O-ND2 3.02Å; T879-L887 HydrophobicContact CG2-CD1 4.41Å
880G76.9Confident83.6Confident34 Ų3457.5 Ų57.535%0.35130%0.303SS..  trans98.7152.3-174.200000112.3S877 E878 E882 N883 A884S877-G880 PolarHBondContact O-N 3.38Å; E878-G880 VanDerWaalsContact C-N 3.26Å; E878-G880 PolarHBondContact O-N 3.29Å; G880-E882 PolarHBondContact O-N 3.26Å; G880-N883 PolarHBondContact O-N 2.98Å; G880-A884 WeakPolarHBondContact O-CB 3.32Å; G880-A884 PolarHBondContact O-N 3.05Å
881S78.6Confident83.8Confident104 Ų10457.5 Ų57.573%0.72730%0.303SS*.Hα-helixtrans-62.3-42.2-172.550.40000113.5E885S881-E885 PolarHBondContact O-N 3.47Å; S881-E885 VanDerWaalsContact O-N 3.16Å
882E78.2Confident84Confident164 Ų16459.8 Ų59.877%0.76631%0.313SS*.Hα-helixtrans-67.6-48.2179.6-64.1-172.4164.100111.7G880 A884 E885 V886G880-E882 PolarHBondContact O-N 3.26Å; E882-A884 VanDerWaalsContact C-N 3.34Å; E882-A884 PolarHBondContact O-N 2.82Å; E882-E885 PolarHBondContact O-N 3.15Å; E882-V886 WeakPolarHBondContact O-CG2 3.49Å; E882-V886 PolarHBondContact O-N 3.17Å
883N76.9Confident84Confident78 Ų7865.2 Ų65.242%0.41734%0.342SS..Hα-helixtrans-63-40.5176.5-76-29.7000111.8T879 G880 E885 V886 L887T879-N883 PolarHBondContact O-ND2 3.02Å; G880-N883 PolarHBondContact O-N 2.98Å; N883-E885 VanDerWaalsContact C-N 3.28Å; N883-E885 PolarHBondContact O-N 3.42Å; N883-V886 PolarHBondContact O-N 2.88Å; N883-L887 WeakPolarHBondContact O-CB 3.45Å; N883-L887 WeakPolarHBondContact O-CG 3.16Å; N883-L887 PolarHBondContact O-N 3.11Å
884A82.7Confident84Confident6 Ų665.2 Ų65.25%0.0534%0.342CS..Hα-helixtrans-58.7-40.7176.200000112V876 G880 E882 L887 R888V876-A884 HydrophobicContact CG1-CB 3.8Å; G880-A884 WeakPolarHBondContact O-CB 3.32Å; G880-A884 PolarHBondContact O-N 3.05Å; E882-A884 VanDerWaalsContact C-N 3.34Å; E882-A884 PolarHBondContact O-N 2.82Å; A884-L887 PolarHBondContact O-N 3.33Å; A884-R888 WeakPolarHBondContact O-CB 3.36Å; A884-R888 VanDerWaalsContact O-CG 3.28Å; A884-R888 WeakPolarHBondContact O-CG 3.27Å; A884-R888 PolarHBondContact O-N 3.26Å
885E85.9Confident84Confident77 Ų7760.3 Ų60.336%0.3632%0.319SS..Hα-helixtrans-67.7-40.9176.6-179.459-162.400112S881 E882 N883 R888 R889S881-E885 PolarHBondContact O-N 3.47Å; S881-E885 VanDerWaalsContact O-N 3.16Å; E882-E885 PolarHBondContact O-N 3.15Å; N883-E885 VanDerWaalsContact C-N 3.28Å; N883-E885 PolarHBondContact O-N 3.42Å; E885-R888 PolarHBondContact O-N 3Å; E885-R889 WeakPolarHBondContact O-CG 3.29Å; E885-R889 PolarHBondContact O-N 2.93Å; E885-R889 VanDerWaalsContact O-N 3.08Å; E885-R889 IonicContact OE1-CZ 3.6Å; E885-R889 IonicContact OE1-NE 3.1Å; E885-R889 PolarHBondContact OE1-NE 3.04Å; E885-R889 VanDerWaalsContact OE1-NE 3.1Å; E885-R889 IonicContact OE1-NH2 3.2Å; E885-R889 PolarHBondContact OE1-NH2 3.01Å
886V86.9Confident84.2Confident74 Ų7461.9 Ų61.945%0.44834%0.336SS..Hα-helixtrans-61.2-47.6174174.40000110.9E882 N883 R888 R889 I890E882-V886 WeakPolarHBondContact O-CG2 3.49Å; E882-V886 PolarHBondContact O-N 3.17Å; N883-V886 PolarHBondContact O-N 2.88Å; V886-R888 VanDerWaalsContact C-N 3.34Å; V886-R888 PolarHBondContact O-N 3.34Å; V886-R889 PolarHBondContact O-N 3.44Å; V886-I890 HydrophobicContact CG1-CD1 4.03Å; V886-I890 WeakPolarHBondContact O-CG1 3.43Å; V886-I890 PolarHBondContact O-N 3.31Å
887L87.5Confident84Confident12 Ų1265 Ų656%0.06336%0.357CS..Hα-helixtrans-62-41.3178.8-67.7171.5000111.4L838 N839 M842 V876 T879 N883 A884 R889 I890 A891L838-L887 HydrophobicContact CB-CD1 4.11Å; N839-L887 HydrophobicContact CB-CD2 3.94Å; M842-L887 HydrophobicContact CE-CB 3.94Å; M842-L887 WeakPolarHBondContact CE-O 3.48Å; M842-L887 HydrophobicContact CG-CB 4.12Å; M842-L887 HydrophobicContact CG-CD2 3.5Å; M842-L887 HydrophobicContact CG-CG 4.37Å; M842-L887 HydrophobicContact SD-CB 4.23Å; M842-L887 HydrophobicContact SD-CD2 4.31Å; V876-L887 HydrophobicContact CG1-CB 4.26Å; V876-L887 HydrophobicContact CG1-CD1 4.09Å; T879-L887 HydrophobicContact CG2-CD1 4.41Å; N883-L887 WeakPolarHBondContact O-CB 3.45Å; N883-L887 WeakPolarHBondContact O-CG 3.16Å; N883-L887 PolarHBondContact O-N 3.11Å; A884-L887 PolarHBondContact O-N 3.33Å; L887-R889 PolarHBondContact O-N 3.27Å; L887-I890 PolarHBondContact O-N 2.8Å; L887-A891 PolarHBondContact O-N 3.2Å
888R89Confident83.9Confident105 Ų10563.8 Ų63.840%0.39634%0.342SS..Hα-helixtrans-57.3-47.7173.8-79.2172.5-176.7174.52.8111.8L865 A884 E885 V886 I890 A891 E892L865-R888 HydrophobicContact CD1-CG 3.98Å; L865-R888 HydrophobicContact CD2-CG 4.4Å; A884-R888 WeakPolarHBondContact O-CB 3.36Å; A884-R888 VanDerWaalsContact O-CG 3.28Å; A884-R888 WeakPolarHBondContact O-CG 3.27Å; A884-R888 PolarHBondContact O-N 3.26Å; E885-R888 PolarHBondContact O-N 3Å; V886-R888 VanDerWaalsContact C-N 3.34Å; V886-R888 PolarHBondContact O-N 3.34Å; R888-I890 VanDerWaalsContact C-N 3.32Å; R888-I890 PolarHBondContact O-N 3.3Å; R888-A891 PolarHBondContact O-N 3.11Å; R888-E892 WeakPolarHBondContact O-CG 3.28Å; R888-E892 PolarHBondContact O-N 3.46Å
889R89.3Confident84Confident141 Ų14168.2 Ų68.253%0.53236%0.357SS..Hα-helixtrans-60.8-40.7177.5-69.6175.1-170.2-178.93.6112.3E885 V886 L887 E892 N893E885-R889 WeakPolarHBondContact O-CG 3.29Å; E885-R889 PolarHBondContact O-N 2.93Å; E885-R889 VanDerWaalsContact O-N 3.08Å; E885-R889 IonicContact OE1-CZ 3.6Å; E885-R889 IonicContact OE1-NE 3.1Å; E885-R889 PolarHBondContact OE1-NE 3.04Å; E885-R889 VanDerWaalsContact OE1-NE 3.1Å; E885-R889 IonicContact OE1-NH2 3.2Å; E885-R889 PolarHBondContact OE1-NH2 3.01Å; V886-R889 PolarHBondContact O-N 3.44Å; L887-R889 PolarHBondContact O-N 3.27Å; R889-E892 PolarHBondContact O-N 3.11Å; R889-N893 VanDerWaalsContact O-CB 3.3Å; R889-N893 WeakPolarHBondContact O-CB 3.4Å; R889-N893 PolarHBondContact O-N 3.41Å; R889-N893 PolarHBondContact O-ND2 2.89Å
890I87.7Confident84Confident52 Ų5269.2 Ų69.227%0.26737%0.366SS..Hα-helixtrans-61.8-46.3177.3-65168.1000110.5N839 M842 V886 L887 R888 N893 A894N839-I890 WeakPolarHBondContact OD1-CD1 3.22Å; M842-I890 HydrophobicContact CB-CB 4.15Å; M842-I890 HydrophobicContact CB-CG2 3.64Å; V886-I890 HydrophobicContact CG1-CD1 4.03Å; V886-I890 WeakPolarHBondContact O-CG1 3.43Å; V886-I890 PolarHBondContact O-N 3.31Å; L887-I890 PolarHBondContact O-N 2.8Å; R888-I890 VanDerWaalsContact C-N 3.32Å; R888-I890 PolarHBondContact O-N 3.3Å; I890-N893 PolarHBondContact O-N 3.07Å; I890-A894 WeakPolarHBondContact O-CB 3.24Å; I890-A894 PolarHBondContact O-N 3.19Å
891A88.5Confident83.5Confident2 Ų270.6 Ų70.62%0.01737%0.37CS..Hα-helixtrans-63.7-41.2177.600000113.2M842 P861 A862 L865 L887 R888 A894 M895M842-A891 HydrophobicContact CE-CB 3.52Å; P861-A891 HydrophobicContact CB-CB 3.94Å; A862-A891 HydrophobicContact CB-CB 4.14Å; L865-A891 HydrophobicContact CD1-CB 4.03Å; L887-A891 PolarHBondContact O-N 3.2Å; R888-A891 PolarHBondContact O-N 3.11Å; A891-A894 PolarHBondContact O-N 3.48Å; A891-M895 PolarHBondContact O-N 3.48Å
892E89.2Confident82.8Confident91 Ų9171.9 Ų71.943%0.42536%0.362SS..Hα-helixtrans-67.5-41.6178.2-70.4-166.9141.300112.1A862 R866 R888 R889 M895 A896A862-E892 HydrophobicContact CB-CG 4.33Å; R866-E892 IonicContact NE-OE1 3.09Å; R866-E892 IonicContact NH2-OE1 3.42Å; R866-E892 PolarHBondContact NH2-OE1 3.32Å; R888-E892 WeakPolarHBondContact O-CG 3.28Å; R888-E892 PolarHBondContact O-N 3.46Å; R889-E892 PolarHBondContact O-N 3.11Å; E892-M895 PolarHBondContact O-N 2.81Å; E892-A896 WeakPolarHBondContact O-CB 3.47Å; E892-A896 PolarHBondContact O-N 3.07Å
893N89.6Confident81.5Confident114 Ų11467 Ų6761%0.6135%0.346SS*.Hα-helixtrans-62.7-42.2174.8-72.2-20.5000111.6R889 I890 A896 S897R889-N893 VanDerWaalsContact O-CB 3.3Å; R889-N893 WeakPolarHBondContact O-CB 3.4Å; R889-N893 PolarHBondContact O-N 3.41Å; R889-N893 PolarHBondContact O-ND2 2.89Å; I890-N893 PolarHBondContact O-N 3.07Å; N893-A896 PolarHBondContact O-N 2.99Å; N893-S897 WeakPolarHBondContact O-CB 3.14Å; N893-S897 PolarHBondContact O-N 3.37Å; N893-S897 PolarHBondContact O-OG 3.25Å
894A85.6Confident80.3Confident13 Ų1372.1 Ų72.111%0.10736%0.36CS..Hα-helixtrans-61.5-47.3175.700000111.3I890 A891 A896 S897 R898I890-A894 WeakPolarHBondContact O-CB 3.24Å; I890-A894 PolarHBondContact O-N 3.19Å; A891-A894 PolarHBondContact O-N 3.48Å; A894-A896 PolarHBondContact O-N 3.11Å; A894-S897 PolarHBondContact O-N 3.23Å; A894-S897 PolarHBondContact O-OG 2.89Å; A894-R898 WeakPolarHBondContact O-CG 3.37Å; A894-R898 PolarHBondContact O-N 3.05Å
895M86.5Confident78.8Confident9 Ų976.4 Ų76.44%0.04439%0.385CS..Hα-helixtrans-60.8-44.7176.3-178.5-171.7-8600112.2E860 A862 I863 A891 E892 S897 R898 R899E860-M895 HydrophobicContact CB-CE 4.06Å; E860-M895 WeakPolarHBondContact OE2-CE 3.21Å; A862-M895 HydrophobicContact CB-CB 4.32Å; A862-M895 HydrophobicContact CB-CE 3.57Å; A862-M895 HydrophobicContact CB-SD 4.09Å; I863-M895 HydrophobicContact CD1-CE 4.12Å; I863-M895 HydrophobicContact CG1-CE 3.51Å; A891-M895 PolarHBondContact O-N 3.48Å; E892-M895 PolarHBondContact O-N 2.81Å; M895-S897 PolarHBondContact O-N 3.46Å; M895-R898 PolarHBondContact O-N 3.23Å; M895-R899 WeakPolarHBondContact O-CG 3.43Å; M895-R899 PolarHBondContact O-N 3.31Å; M895-R899 VanDerWaalsContact O-N 3.08Å
896A86.4Confident77Confident59 Ų5978.3 Ų78.349%0.48840%0.398SS..Hα-helixtrans-62.1-43.6178.900000111.8E892 N893 A894 R898 R899 S900E892-A896 WeakPolarHBondContact O-CB 3.47Å; E892-A896 PolarHBondContact O-N 3.07Å; N893-A896 PolarHBondContact O-N 2.99Å; A894-A896 PolarHBondContact O-N 3.11Å; A896-R898 VanDerWaalsContact C-N 3.33Å; A896-R898 PolarHBondContact O-N 3Å; A896-R899 PolarHBondContact O-N 3.08Å; A896-S900 PolarHBondContact O-N 3.06Å
897S82.7Confident75.3Confident65 Ų6581.3 Ų81.346%0.45541%0.411SS..Hα-helixtrans-59.4-42.1177.874.90000112N893 A894 M895 S900 S901N893-S897 WeakPolarHBondContact O-CB 3.14Å; N893-S897 PolarHBondContact O-N 3.37Å; N893-S897 PolarHBondContact O-OG 3.25Å; A894-S897 PolarHBondContact O-N 3.23Å; A894-S897 PolarHBondContact O-OG 2.89Å; M895-S897 PolarHBondContact O-N 3.46Å; S897-S900 PolarHBondContact O-N 3.1Å; S897-S900 PolarHBondContact O-OG 2.94Å; S897-S901 PolarHBondContact O-N 3.37Å; S897-S901 VanDerWaalsContact O-N 3.07Å; S897-S901 PolarHBondContact O-OG 2.85Å
898R80.2Confident73.4Confident43 Ų4387.8 Ų87.816%0.16245%0.446CS..Hα-helixtrans-69.7-36.7178.5-67.2177.4-161.8138.78.1113.6D843 C844 D845 A894 M895 A896 S900 S901 K902D843-R898 PolarHBondContact O-NH2 3Å; C844-R898 VanDerWaalsContact O-CZ 3.28Å; C844-R898 PolarHBondContact O-NH1 3.31Å; C844-R898 PolarHBondContact O-NH2 3.37Å; D845-R898 VanDerWaalsContact CA-CZ 3.49Å; D845-R898 VanDerWaalsContact CA-NH1 3.33Å; D845-R898 PolarHBondContact O-NH1 3.03Å; D845-R898 WeakPolarHBondContact OD1-CD 3.16Å; D845-R898 IonicContact OD1-CZ 2.95Å; D845-R898 IonicContact OD1-NE 3.32Å; D845-R898 PolarHBondContact OD1-NE 3.39Å; D845-R898 IonicContact OD1-NH1 2.75Å; D845-R898 IonicContact OD1-NH2 3.7Å; A894-R898 WeakPolarHBondContact O-CG 3.37Å; A894-R898 PolarHBondContact O-N 3.05Å; M895-R898 PolarHBondContact O-N 3.23Å; A896-R898 VanDerWaalsContact C-N 3.33Å; A896-R898 PolarHBondContact O-N 3Å; R898-S900 VanDerWaalsContact C-N 3.34Å; R898-S901 WeakPolarHBondContact CA-OG 3.14Å; R898-S901 PolarHBondContact O-N 2.82Å; R898-S901 PolarHBondContact O-OG 3.36Å; R898-K902 WeakPolarHBondContact O-CG 3.46Å; R898-K902 PolarHBondContact O-N 2.75Å
899R81Confident71.2Confident150 Ų15085.9 Ų85.957%0.56646%0.459SS*.Hα-helixtrans-66.8-39.4175.6-72.6-178.2-178.7-169.7-0.2111M895 A896 S901 K902 S903M895-R899 WeakPolarHBondContact O-CG 3.43Å; M895-R899 PolarHBondContact O-N 3.31Å; M895-R899 VanDerWaalsContact O-N 3.08Å; A896-R899 PolarHBondContact O-N 3.08Å; R899-S901 VanDerWaalsContact C-N 3.35Å; R899-S901 PolarHBondContact O-N 3.41Å; R899-K902 PolarHBondContact O-N 2.99Å; R899-S903 PolarHBondContact O-N 3.28Å
900S74Confident68.6Low61 Ų6188.4 Ų88.443%0.42750%0.496SS..Hα-helixtrans-66.5-33.3175.278.20000113.4A896 S897 R898 S903 R904A896-S900 PolarHBondContact O-N 3.06Å; S897-S900 PolarHBondContact O-N 3.1Å; S897-S900 PolarHBondContact O-OG 2.94Å; R898-S900 VanDerWaalsContact C-N 3.34Å; S900-S903 PolarHBondContact O-OG 3.09Å; S900-S903 VanDerWaalsContact O-OG 3.13Å; S900-R904 WeakPolarHBondContact O-CG 3.36Å; S900-R904 PolarHBondContact O-N 3.42Å
901S68.1Low67.7Low63 Ų6390.2 Ų90.244%0.44151%0.507SS..Hα-helixtrans-73.5-36.2175.160.20000112.3S897 R898 R899 T905S897-S901 PolarHBondContact O-N 3.37Å; S897-S901 VanDerWaalsContact O-N 3.07Å; S897-S901 PolarHBondContact O-OG 2.85Å; R898-S901 WeakPolarHBondContact CA-OG 3.14Å; R898-S901 PolarHBondContact O-N 2.82Å; R898-S901 PolarHBondContact O-OG 3.36Å; R899-S901 VanDerWaalsContact C-N 3.35Å; R899-S901 PolarHBondContact O-N 3.41Å; S901-T905 PolarHBondContact O-N 2.86Å; S901-T905 PolarHBondContact O-OG1 2.83Å
902K62.3Low66.6Low131 Ų13194.8 Ų94.857%0.5753%0.533SS*.Hα-helixtrans-67.2-41.5175.7-77.9180179.4175.20112.3R898 R899 R904 T905 D906R898-K902 WeakPolarHBondContact O-CG 3.46Å; R898-K902 PolarHBondContact O-N 2.75Å; R899-K902 PolarHBondContact O-N 2.99Å; K902-R904 VanDerWaalsContact C-N 3.31Å; K902-R904 PolarHBondContact O-N 3.17Å; K902-T905 WeakPolarHBondContact CA-OG1 3.48Å; K902-T905 PolarHBondContact O-N 3.49Å; K902-T905 PolarHBondContact O-OG1 3.28Å; K902-D906 PolarHBondContact O-N 3.29Å; K902-D906 VanDerWaalsContact O-N 3.11Å
903S52.5Low65.3Low60 Ų6095.1 Ų95.142%0.4254%0.539SS..Hα-helixtrans-65-35.7177.969.10000112.4R899 S900 T905 D906 D907R899-S903 PolarHBondContact O-N 3.28Å; S900-S903 PolarHBondContact O-OG 3.09Å; S900-S903 VanDerWaalsContact O-OG 3.13Å; S903-T905 VanDerWaalsContact C-N 3.34Å; S903-T905 PolarHBondContact O-N 3.29Å; S903-D906 PolarHBondContact O-N 3.39Å; S903-D907 PolarHBondContact O-N 3.23Å; S903-D907 VanDerWaalsContact O-N 3.11Å
904R50.2Low63.9Low187 Ų18793.9 Ų93.971%0.70654%0.535SS*.Hα-helixtrans-70.3-25.9176-77.3-178.3176.6175.70.6114.2S900 K902 N908S900-R904 WeakPolarHBondContact O-CG 3.36Å; S900-R904 PolarHBondContact O-N 3.42Å; K902-R904 VanDerWaalsContact C-N 3.31Å; K902-R904 PolarHBondContact O-N 3.17Å; R904-N908 PolarHBondContact O-ND2 3.17Å
905T52.5Low62.5Low95 Ų9599 Ų9958%0.58356%0.562SS**Hα-helixtrans-80-32.8174.244.30000111.9S901 K902 S903S901-T905 PolarHBondContact O-N 2.86Å; S901-T905 PolarHBondContact O-OG1 2.83Å; K902-T905 WeakPolarHBondContact CA-OG1 3.48Å; K902-T905 PolarHBondContact O-N 3.49Å; K902-T905 PolarHBondContact O-OG1 3.28Å; S903-T905 VanDerWaalsContact C-N 3.34Å; S903-T905 PolarHBondContact O-N 3.29Å
906D47.5Very low60.9Low118 Ų118105 Ų10563%0.63160%0.596SS**Hα-helixtrans-75.5-34.1179.3-65.4-16.7000112K902 S903 N908 G909K902-D906 PolarHBondContact O-N 3.29Å; K902-D906 VanDerWaalsContact O-N 3.11Å; S903-D906 PolarHBondContact O-N 3.39Å; D906-N908 VanDerWaalsContact C-N 3.31Å; D906-N908 PolarHBondContact O-N 2.89Å; D906-G909 PolarHBondContact O-N 3.24Å
907D50.5Low59.1Low137 Ų137108.3 Ų108.373%0.73360%0.604SS**THydrogen-bonded Turntrans-73.9-15.4177.2-80.3-21.9000114.5S903S903-D907 PolarHBondContact O-N 3.23Å; S903-D907 VanDerWaalsContact O-N 3.11Å
908N48.5Very low57.3Low148 Ų148111.6 Ų111.679%0.79162%0.616SS**THydrogen-bonded Turntrans-100.75.9176.9-75.3-48.1000113.3R904 D906R904-N908 PolarHBondContact O-ND2 3.17Å; D906-N908 VanDerWaalsContact C-N 3.31Å; D906-N908 PolarHBondContact O-N 2.89Å
909G43Very low55.4Low65 Ų65117.3 Ų117.367%0.6765%0.653SS**  trans-110.16.9-176.400000115.7D906D906-G909 PolarHBondContact O-N 3.24Å
910C34.6Very low53.1Low193 Ų193114.4 Ų114.4100%1.30466%0.661SS**  trans-109.60173.3-89.40000111.8

Retrieved 910 of 910 residues in 456.5 ms (Link to these results)