A0A077ZCM7_TRITR Loading...

Polyubiquitin

AlphaFold DB , UniProt , Accession A0A077ZCM7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 608 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M92.6Very high91Very high66 Ų6666.9 Ų66.933%0.32536%0.357SS..  0155.7067.6178.8179.200110I3 V17 P19 L56 I61 K63M1-I3 HydrophobicContact CE-CG2 4.29Å; M1-V17 HydrophobicContact CE-CG2 4.1Å; M1-V17 HydrophobicContact CG-CG2 4.01Å; M1-V17 WeakPolarHBondContact CG-O 3.47Å; M1-V17 PolarHBondContact N-O 3.45Å; M1-V17 PolarHBondContact O-N 2.94Å; M1-P19 HydrophobicContact CE-CB 4.39Å; M1-P19 HydrophobicContact CE-CG 4Å; M1-P19 HydrophobicContact SD-CG 4.06Å; M1-L56 HydrophobicContact CE-CD1 4.2Å; M1-I61 WeakPolarHBondContact CE-O 3.31Å; M1-K63 HydrophobicContact CB-CB 4.18Å; M1-K63 HydrophobicContact CB-CG 4.11Å; M1-K63 HydrophobicContact SD-CB 4.5Å; M1-K63 PolarHBondContact SD-N 3.34Å
2Q94.4Very high91.1Very high80 Ų8066.8 Ų66.837%0.37436%0.361SS..EExtended strand (participates in β ladder)trans-95.9136.6175.6-75.9177.74.800110.5T14 L15 E16 E64Q2-T14 HydrophobicContact CB-CG2 4.46Å; Q2-T14 HydrophobicContact CG-CG2 4.44Å; Q2-L15 WeakPolarHBondContact CA-O 3.45Å; Q2-E16 HydrophobicContact CG-CG 3.92Å; Q2-E16 PolarHBondContact NE2-OE1 2.99Å; Q2-E64 PolarHBondContact O-N 3.21Å
3I96.9Very high91.3Very high0 Ų061.9 Ų61.90%034%0.335CS..EExtended strand (participates in β ladder)trans-126.6160.3170.663.9167.7000109.9M1 L15 V17 V26 L56 I61 L67M1-I3 HydrophobicContact CE-CG2 4.29Å; I3-L15 HydrophobicContact CG1-CB 4.08Å; I3-L15 PolarHBondContact N-O 3.3Å; I3-L15 PolarHBondContact O-N 3.34Å; I3-V17 HydrophobicContact CB-CG2 4.35Å; I3-V17 HydrophobicContact CD1-CG1 4.03Å; I3-V17 HydrophobicContact CD1-CG2 3.84Å; I3-V17 HydrophobicContact CG1-CG1 4.19Å; I3-V17 HydrophobicContact CG1-CG2 3.74Å; I3-V17 HydrophobicContact CG2-CG2 3.77Å; I3-V26 HydrophobicContact CD1-CG1 4.41Å; I3-L56 HydrophobicContact CD1-CD1 4.49Å; I3-I61 HydrophobicContact CG2-CG2 4.13Å; I3-L67 HydrophobicContact CD1-CD1 4.08Å; I3-L67 HydrophobicContact CD1-CD2 4.41Å
4F97.2Very high91.6Very high57 Ų5761.2 Ų61.225%0.2533%0.334CS..EExtended strand (participates in β ladder)trans-111.9139.3177.2-56.8-72.2000110.6T12 I13 T14 E64 S65 T66 L67F4-T12 HydrophobicContact CB-CG2 4.04Å; F4-T12 HydrophobicContact CD1-CG2 4.1Å; F4-T12 HydrophobicContact CG-CG2 4.42Å; F4-I13 CarbonylContact C-O 3.58Å; F4-I13 WeakPolarHBondContact CA-O 3.31Å; F4-T14 HydrophobicContact CD1-CG2 4.27Å; F4-T14 HydrophobicContact CE1-CG2 4.03Å; F4-E64 HydrophobicContact CE2-CB 3.94Å; F4-E64 HydrophobicContact CE2-CG 4.14Å; F4-S65 PolarHBondContact N-O 2.82Å; F4-T66 HydrophobicContact CB-CG2 4.43Å; F4-T66 CarbonylContact O-C 3.6Å; F4-T66 WeakPolarHBondContact O-CA 3.44Å; F4-L67 PolarHBondContact O-N 3.43Å
5V96.5Very high91.8Very high0 Ų057.5 Ų57.50%031%0.313CS..EExtended strand (participates in β ladder)trans-119.5112.6174-177.60000108.1T12 I13 L15 I30 L43 L67 L69V5-T12 CarbonylContact O-C 3.51Å; V5-T12 WeakPolarHBondContact O-CA 3.41Å; V5-I13 HydrophobicContact CB-CB 4.26Å; V5-I13 HydrophobicContact CG1-CD1 4.5Å; V5-I13 PolarHBondContact N-O 3.35Å; V5-I13 PolarHBondContact O-N 2.82Å; V5-L15 HydrophobicContact CG2-CD1 3.7Å; V5-L15 HydrophobicContact CG2-CG 4.48Å; V5-I30 HydrophobicContact CG1-CD1 4.24Å; V5-I30 HydrophobicContact CG2-CD1 4.24Å; V5-L43 HydrophobicContact CG1-CD2 4.08Å; V5-L67 CarbonylContact C-O 3.54Å; V5-L67 WeakPolarHBondContact CA-O 3.08Å; V5-L67 HydrophobicContact CG2-CB 4.4Å; V5-L69 HydrophobicContact CG1-CB 3.55Å; V5-L69 HydrophobicContact CG1-CD2 4.34Å; V5-L69 HydrophobicContact CG1-CG 4.5Å
6K94.6Very high92.1Very high92 Ų9262.5 Ų62.540%0.433%0.334SS..EExtended strand (participates in β ladder)trans-99.3129.3179.5-114.3179.7178.5176.10110.9K11 T12 T66 L67 H68 L69K6-K11 WeakPolarHBondContact CA-O 3.15Å; K6-T12 VanDerWaalsContact CE-OG1 3.23Å; K6-T12 WeakPolarHBondContact CE-OG1 3.27Å; K6-T12 HydrophobicContact CG-CG2 4.32Å; K6-T12 VanDerWaalsContact CG-OG1 3.29Å; K6-T12 WeakPolarHBondContact CG-OG1 3.19Å; K6-T66 HydrophobicContact CB-CG2 4.09Å; K6-T66 HydrophobicContact CD-CG2 4.33Å; K6-L67 PolarHBondContact N-O 3.37Å; K6-H68 CarbonylContact O-C 3.5Å; K6-H68 WeakPolarHBondContact O-CA 3.44Å; K6-L69 PolarHBondContact O-N 3.44Å
7T89.4Confident92.3Very high21 Ų2159 Ų5913%0.12932%0.315CS..EExtended strand (participates in β ladder)trans-82.3162.2170.370.70000110.5T9 G10 K11 I13 L69T7-T9 PolarHBondContact O-N 2.66Å; T7-T9 VanDerWaalsContact O-N 3.16Å; T7-T9 PolarHBondContact OG1-N 2.75Å; T7-T9 PolarHBondContact OG1-OG1 2.89Å; T7-G10 PolarHBondContact O-N 3.01Å; T7-K11 HydrophobicContact CG2-CB 4.36Å; T7-K11 PolarHBondContact N-O 2.74Å; T7-K11 WeakPolarHBondContact OG1-CB 3.49Å; T7-K11 PolarHBondContact OG1-N 2.72Å; T7-K11 PolarHBondContact OG1-O 3.41Å; T7-I13 HydrophobicContact CG2-CD1 4.33Å; T7-L69 HydrophobicContact CG2-CD2 4.37Å
8L82.7Confident92.4Very high140 Ų14062.4 Ų62.473%0.73333%0.329SS*.THydrogen-bonded Turntrans-61.8-19.1173.4-65.9174.8000113.6G10 V70L8-G10 VanDerWaalsContact C-N 3.28Å; L8-V70 HydrophobicContact CD1-CG1 4.49Å; L8-V70 HydrophobicContact CD1-CG2 4.43Å
9T82.1Confident92.6Very high128 Ų12862.5 Ų62.579%0.78533%0.334SS*.THydrogen-bonded Turntrans-81.4-5.3176.169.30000113.3T7T7-T9 PolarHBondContact O-N 2.66Å; T7-T9 VanDerWaalsContact O-N 3.16Å; T7-T9 PolarHBondContact OG1-N 2.75Å; T7-T9 PolarHBondContact OG1-OG1 2.89Å
10G84.1Confident92.8Very high46 Ų4663.3 Ų63.347%0.47434%0.344SS..SBendtrans93.1-11.5-177.900000114.8T7 L8 T12T7-G10 PolarHBondContact O-N 3.01Å; L8-G10 VanDerWaalsContact C-N 3.28Å; G10-T12 PolarHBondContact O-N 3.16Å
11K90.8Very high92.9Very high106 Ų10661.3 Ų61.346%0.46133%0.333SS..  trans-59.5133.2172.8-172.2-179.3-179.6-175.20110.5K6 T7 E34K6-K11 WeakPolarHBondContact CA-O 3.15Å; T7-K11 HydrophobicContact CG2-CB 4.36Å; T7-K11 PolarHBondContact N-O 2.74Å; T7-K11 WeakPolarHBondContact OG1-CB 3.49Å; T7-K11 PolarHBondContact OG1-N 2.72Å; T7-K11 PolarHBondContact OG1-O 3.41Å; K11-E34 WeakPolarHBondContact CE-OE2 3.47Å; K11-E34 IonicContact NZ-OE1 2.81Å; K11-E34 PolarHBondContact NZ-OE1 3.45Å; K11-E34 IonicContact NZ-OE2 2.81Å; K11-E34 PolarHBondContact NZ-OE2 3.33Å
12T92.5Very high93.1Very high66 Ų6659.3 Ų59.341%0.40533%0.326SS..EExtended strand (participates in β ladder)trans-114.5128.5179.1-53.30000110.1F4 V5 K6 G10F4-T12 HydrophobicContact CB-CG2 4.04Å; F4-T12 HydrophobicContact CD1-CG2 4.1Å; F4-T12 HydrophobicContact CG-CG2 4.42Å; V5-T12 CarbonylContact O-C 3.51Å; V5-T12 WeakPolarHBondContact O-CA 3.41Å; K6-T12 VanDerWaalsContact CE-OG1 3.23Å; K6-T12 WeakPolarHBondContact CE-OG1 3.27Å; K6-T12 HydrophobicContact CG-CG2 4.32Å; K6-T12 VanDerWaalsContact CG-OG1 3.29Å; K6-T12 WeakPolarHBondContact CG-OG1 3.19Å; G10-T12 PolarHBondContact O-N 3.16Å
13I93Very high93.3Very high3 Ų355.5 Ų55.52%0.01531%0.308CS..EExtended strand (participates in β ladder)trans-112.8126.5-179.6-54152000107.9F4 V5 T7 L15 K33 E34 L69F4-I13 CarbonylContact C-O 3.58Å; F4-I13 WeakPolarHBondContact CA-O 3.31Å; V5-I13 HydrophobicContact CB-CB 4.26Å; V5-I13 HydrophobicContact CG1-CD1 4.5Å; V5-I13 PolarHBondContact N-O 3.35Å; V5-I13 PolarHBondContact O-N 2.82Å; T7-I13 HydrophobicContact CG2-CD1 4.33Å; I13-L15 HydrophobicContact CG2-CD2 4.35Å; I13-L15 HydrophobicContact CG2-CG 4.44Å; I13-K33 HydrophobicContact CG2-CD 3.97Å; I13-K33 HydrophobicContact CG2-CG 4.45Å; I13-E34 HydrophobicContact CD1-CG 3.65Å; I13-E34 HydrophobicContact CG1-CG 3.97Å; I13-E34 HydrophobicContact CG2-CG 4.16Å; I13-L69 HydrophobicContact CD1-CD2 4.45Å
14T95.9Very high93.2Very high52 Ų5260.5 Ų60.532%0.31933%0.332SS..EExtended strand (participates in β ladder)trans-95.4130.7176.9-51.80000110.1Q2 F4 K33Q2-T14 HydrophobicContact CB-CG2 4.46Å; Q2-T14 HydrophobicContact CG-CG2 4.44Å; F4-T14 HydrophobicContact CD1-CG2 4.27Å; F4-T14 HydrophobicContact CE1-CG2 4.03Å; T14-K33 PolarHBondContact O-NZ 3.25Å
15L95Very high93.1Very high6 Ų661.4 Ų61.43%0.03134%0.339CS..EExtended strand (participates in β ladder)trans-124143.1178.2-64.5170.9000111.5Q2 I3 V5 I13 V17 V26 K29 I30 K33Q2-L15 WeakPolarHBondContact CA-O 3.45Å; I3-L15 HydrophobicContact CG1-CB 4.08Å; I3-L15 PolarHBondContact N-O 3.3Å; I3-L15 PolarHBondContact O-N 3.34Å; V5-L15 HydrophobicContact CG2-CD1 3.7Å; V5-L15 HydrophobicContact CG2-CG 4.48Å; I13-L15 HydrophobicContact CG2-CD2 4.35Å; I13-L15 HydrophobicContact CG2-CG 4.44Å; L15-V17 HydrophobicContact CB-CG1 4.1Å; L15-V26 HydrophobicContact CD1-CG1 4.14Å; L15-K29 HydrophobicContact CD2-CB 4.23Å; L15-I30 HydrophobicContact CD1-CD1 4.15Å; L15-I30 HydrophobicContact CD1-CG1 3.54Å; L15-K33 HydrophobicContact CD2-CD 3.93Å
16E95.8Very high93.1Very high137 Ų13761.4 Ų61.464%0.6434%0.339SS*.EExtended strand (participates in β ladder)trans-95.2118.3167.1-68.1-163.8160.700110.3Q2 K29Q2-E16 HydrophobicContact CG-CG 3.92Å; Q2-E16 PolarHBondContact NE2-OE1 2.99Å; E16-K29 PolarHBondContact O-NZ 3.04Å
17V95.4Very high93.1Very high3 Ų357.4 Ų57.42%0.01832%0.322CS..  trans-137.7157.1-172.6-60.80000111.2M1 I3 L15 D21 V26 K29 L56M1-V17 HydrophobicContact CE-CG2 4.1Å; M1-V17 HydrophobicContact CG-CG2 4.01Å; M1-V17 WeakPolarHBondContact CG-O 3.47Å; M1-V17 PolarHBondContact N-O 3.45Å; M1-V17 PolarHBondContact O-N 2.94Å; I3-V17 HydrophobicContact CB-CG2 4.35Å; I3-V17 HydrophobicContact CD1-CG1 4.03Å; I3-V17 HydrophobicContact CD1-CG2 3.84Å; I3-V17 HydrophobicContact CG1-CG1 4.19Å; I3-V17 HydrophobicContact CG1-CG2 3.74Å; I3-V17 HydrophobicContact CG2-CG2 3.77Å; L15-V17 HydrophobicContact CB-CG1 4.1Å; V17-D21 VanDerWaalsContact CA-OD2 3.26Å; V17-D21 WeakPolarHBondContact CA-OD2 3.49Å; V17-D21 WeakPolarHBondContact CB-OD2 3.38Å; V17-V26 HydrophobicContact CG1-CG2 4.22Å; V17-K29 HydrophobicContact CG1-CD 4.22Å; V17-L56 HydrophobicContact CB-CD1 3.7Å; V17-L56 HydrophobicContact CG1-CD1 4.31Å; V17-L56 HydrophobicContact CG2-CD1 3.48Å; V17-L56 VanDerWaalsContact CG2-CD1 3.48Å
18E95.3Very high93.3Very high120 Ų12059.1 Ų59.156%0.56133%0.33SS*.  trans-102.9148.6168.4-63.7-169.2168.300110.4S20 D21E18-S20 PolarHBondContact O-N 3.43Å; E18-D21 PolarHBondContact N-OD2 2.98Å; E18-D21 VanDerWaalsContact O-CB 3.29Å; E18-D21 WeakPolarHBondContact O-CB 3.35Å; E18-D21 PolarHBondContact O-N 3.19Å
19P94.8Very high93.9Very high64 Ų6455.6 Ų55.642%0.41631%0.309SS..THydrogen-bonded Turntrans-55.7-25.2177.1-25.634.4000114.2M1 S57M1-P19 HydrophobicContact CE-CB 4.39Å; M1-P19 HydrophobicContact CE-CG 4Å; M1-P19 HydrophobicContact SD-CG 4.06Å; P19-S57 VanDerWaalsContact O-CB 3.31Å; P19-S57 WeakPolarHBondContact O-CB 3.4Å; P19-S57 PolarHBondContact O-N 2.81Å
20S96.2Very high94.5Very high78 Ų7849.5 Ų49.555%0.54527%0.271SS..THydrogen-bonded Turntrans-78.9-10.9174.9420000114.6E18 S22 T55E18-S20 PolarHBondContact O-N 3.43Å; S20-S22 PolarHBondContact O-N 3.17Å; S20-T55 WeakPolarHBondContact O-CG2 3.47Å
21D96.3Very high94.9Very high22 Ų2249.7 Ų49.712%0.11826%0.26CS..  trans-60.7131.3177.6-77.4-20.8000109.8V17 E18 V26 K29 T55 L56V17-D21 VanDerWaalsContact CA-OD2 3.26Å; V17-D21 WeakPolarHBondContact CA-OD2 3.49Å; V17-D21 WeakPolarHBondContact CB-OD2 3.38Å; E18-D21 PolarHBondContact N-OD2 2.98Å; E18-D21 VanDerWaalsContact O-CB 3.29Å; E18-D21 WeakPolarHBondContact O-CB 3.35Å; E18-D21 PolarHBondContact O-N 3.19Å; D21-V26 HydrophobicContact CB-CG2 4.22Å; D21-K29 IonicContact OD2-NZ 2.86Å; D21-K29 PolarHBondContact OD2-NZ 2.97Å; D21-T55 CarbonylContact O-C 3.58Å; D21-T55 VanDerWaalsContact O-CA 3.28Å; D21-T55 WeakPolarHBondContact O-CA 3.46Å; D21-L56 HydrophobicContact CB-CD1 4.25Å; D21-L56 PolarHBondContact O-N 2.79Å
22S97.2Very high94.7Very high25 Ų2551.2 Ų51.218%0.17527%0.273CS..BIsolated β-bridgetrans-67.3154.9169.566.50000110.8S20 E24 N25 V26 R54S20-S22 PolarHBondContact O-N 3.17Å; S22-E24 PolarHBondContact O-N 3.24Å; S22-N25 PolarHBondContact O-N 3.11Å; S22-N25 VanDerWaalsContact O-N 3.11Å; S22-N25 WeakPolarHBondContact OG-CB 3.39Å; S22-N25 PolarHBondContact OG-N 2.83Å; S22-N25 VanDerWaalsContact OG-N 3.12Å; S22-N25 PolarHBondContact OG-OD1 3.26Å; S22-V26 WeakPolarHBondContact O-CG2 3.43Å; S22-V26 PolarHBondContact O-N 3.33Å; S22-R54 CarbonylContact C-O 3.54Å; S22-R54 VanDerWaalsContact CA-O 3.28Å; S22-R54 WeakPolarHBondContact CA-O 3.42Å
23I96.9Very high94.5Very high0 Ų053.7 Ų53.70%028%0.278CS..Hα-helixtrans-61.1-34.5175.1-61-54.5000111V26 K27 L43 L50 E51 R54 L56 Y59I23-V26 PolarHBondContact O-N 2.82Å; I23-K27 WeakPolarHBondContact O-CG 3.4Å; I23-K27 PolarHBondContact O-N 2.88Å; I23-L43 HydrophobicContact CG2-CD1 4.26Å; I23-L50 HydrophobicContact CB-CB 4.48Å; I23-L50 HydrophobicContact CD1-CB 3.95Å; I23-L50 HydrophobicContact CD1-CD1 3.7Å; I23-L50 HydrophobicContact CD1-CG 4.33Å; I23-L50 HydrophobicContact CG1-CB 3.91Å; I23-L50 HydrophobicContact CG2-CB 3.75Å; I23-E51 WeakPolarHBondContact CB-O 3.46Å; I23-E51 WeakPolarHBondContact CG1-O 3.46Å; I23-R54 WeakPolarHBondContact CG1-O 3.35Å; I23-R54 PolarHBondContact N-O 2.79Å; I23-L56 HydrophobicContact CD1-CD2 3.82Å; I23-L56 HydrophobicContact CD1-CG 4.5Å; I23-Y59 HydrophobicContact CD1-CD2 4.31Å; I23-Y59 HydrophobicContact CD1-CE2 4.44Å; I23-Y59 HydrophobicContact CG1-CD2 4.45Å; I23-Y59 HydrophobicContact CG1-CE2 4.11Å
24E95.4Very high94.3Very high104 Ų10456.4 Ų56.449%0.48629%0.291SS..Hα-helixtrans-59.3-46.4171.5-171.4172.9-165.100112.5S22 V26 K27 N28 D52S22-E24 PolarHBondContact O-N 3.24Å; E24-V26 VanDerWaalsContact C-N 3.29Å; E24-V26 PolarHBondContact O-N 2.76Å; E24-K27 WeakPolarHBondContact O-CB 3.3Å; E24-K27 PolarHBondContact O-N 2.81Å; E24-K27 VanDerWaalsContact O-N 3.09Å; E24-N28 PolarHBondContact O-N 2.77Å; E24-D52 HydrophobicContact CB-CB 4.22Å; E24-D52 PolarHBondContact N-O 2.89Å; E24-D52 VanDerWaalsContact N-O 3.17Å
25N95.5Very high93.8Very high76 Ų7656.8 Ų56.841%0.40631%0.305SS..Hα-helixtrans-62.9-37.4176.8-73.8-6000111.9S22 K27 N28 K29S22-N25 PolarHBondContact O-N 3.11Å; S22-N25 VanDerWaalsContact O-N 3.11Å; S22-N25 WeakPolarHBondContact OG-CB 3.39Å; S22-N25 PolarHBondContact OG-N 2.83Å; S22-N25 VanDerWaalsContact OG-N 3.12Å; S22-N25 PolarHBondContact OG-OD1 3.26Å; N25-K27 VanDerWaalsContact C-N 3.31Å; N25-K27 PolarHBondContact O-N 2.82Å; N25-N28 PolarHBondContact O-N 2.95Å; N25-K29 WeakPolarHBondContact O-CG 3.5Å; N25-K29 PolarHBondContact O-N 2.92Å
26V96.4Very high93.3Very high0 Ų057.8 Ų57.80%031%0.31CS..Hα-helixtrans-63.1-40.2174.5177.70000110.8I3 L15 V17 D21 S22 I23 E24 K29 I30 L43 L56I3-V26 HydrophobicContact CD1-CG1 4.41Å; L15-V26 HydrophobicContact CD1-CG1 4.14Å; V17-V26 HydrophobicContact CG1-CG2 4.22Å; D21-V26 HydrophobicContact CB-CG2 4.22Å; S22-V26 WeakPolarHBondContact O-CG2 3.43Å; S22-V26 PolarHBondContact O-N 3.33Å; I23-V26 PolarHBondContact O-N 2.82Å; E24-V26 VanDerWaalsContact C-N 3.29Å; E24-V26 PolarHBondContact O-N 2.76Å; V26-K29 PolarHBondContact O-N 3.24Å; V26-I30 HydrophobicContact CG1-CD1 4.36Å; V26-I30 WeakPolarHBondContact O-CG1 3.38Å; V26-I30 PolarHBondContact O-N 3.47Å; V26-L43 HydrophobicContact CB-CD1 4.42Å; V26-L43 HydrophobicContact CG1-CD1 3.89Å; V26-L56 HydrophobicContact CG2-CD1 3.91Å; V26-L56 HydrophobicContact CG2-CD2 4.06Å; V26-L56 HydrophobicContact CG2-CG 4.03Å
27K95.2Very high92.8Very high9 Ų952 Ų524%0.03928%0.284CS..Hα-helixtrans-63.9-40.7175.1-70.3172.4163-168.30112.5I23 E24 N25 K29 I30 Q31 P38 Q41 L43 D52I23-K27 WeakPolarHBondContact O-CG 3.4Å; I23-K27 PolarHBondContact O-N 2.88Å; E24-K27 WeakPolarHBondContact O-CB 3.3Å; E24-K27 PolarHBondContact O-N 2.81Å; E24-K27 VanDerWaalsContact O-N 3.09Å; N25-K27 VanDerWaalsContact C-N 3.31Å; N25-K27 PolarHBondContact O-N 2.82Å; K27-K29 VanDerWaalsContact C-N 3.33Å; K27-K29 PolarHBondContact O-N 3.14Å; K27-I30 WeakPolarHBondContact O-CA 3.45Å; K27-I30 WeakPolarHBondContact O-CB 3.38Å; K27-I30 PolarHBondContact O-N 3.32Å; K27-I30 VanDerWaalsContact O-N 3.09Å; K27-Q31 PolarHBondContact O-N 3.29Å; K27-P38 HydrophobicContact CB-CB 3.86Å; K27-P38 HydrophobicContact CB-CG 4.42Å; K27-P38 HydrophobicContact CD-CB 4.26Å; K27-P38 PolarHBondContact NZ-O 3.41Å; K27-Q41 HydrophobicContact CD-CB 4.35Å; K27-Q41 WeakPolarHBondContact CE-O 3.44Å; K27-Q41 HydrophobicContact CG-CB 4.1Å; K27-Q41 PolarHBondContact NZ-O 2.88Å; K27-Q41 VanDerWaalsContact NZ-O 3.14Å; K27-Q41 PolarHBondContact O-NE2 3.17Å; K27-Q41 PolarHBondContact O-OE1 2.73Å; K27-L43 HydrophobicContact CG-CD1 3.98Å; K27-D52 WeakPolarHBondContact CD-OD1 3.43Å; K27-D52 WeakPolarHBondContact CE-OD1 3.39Å; K27-D52 VanDerWaalsContact NZ-CG 3.3Å; K27-D52 IonicContact NZ-OD1 3.05Å; K27-D52 PolarHBondContact NZ-OD1 3.06Å; K27-D52 IonicContact NZ-OD2 3.96Å; K27-D52 PolarHBondContact NZ-OD2 2.96Å; K27-D52 VanDerWaalsContact NZ-OD2 3.1Å
28N93.6Very high92.5Very high56 Ų5652.8 Ų52.830%0.29929%0.29SS..Hα-helixtrans-61.3-42.8174.6-64.7-20.2000111E24 N25 I30 Q31 D32 P38E24-N28 PolarHBondContact O-N 2.77Å; N25-N28 PolarHBondContact O-N 2.95Å; N28-I30 PolarHBondContact O-N 3.43Å; N28-Q31 WeakPolarHBondContact O-CA 3.47Å; N28-Q31 WeakPolarHBondContact O-CB 3.47Å; N28-Q31 PolarHBondContact O-N 3.01Å; N28-D32 PolarHBondContact O-N 2.78Å; N28-P38 WeakPolarHBondContact OD1-CG 3.37Å
29K95.7Very high92.1Very high67 Ų6749.7 Ų49.729%0.29128%0.277SS..Hα-helixtrans-61.7-31.2173.8-68-179.8177.4-1780113.1L15 E16 V17 D21 N25 V26 K27 K33L15-K29 HydrophobicContact CD2-CB 4.23Å; E16-K29 PolarHBondContact O-NZ 3.04Å; V17-K29 HydrophobicContact CG1-CD 4.22Å; D21-K29 IonicContact OD2-NZ 2.86Å; D21-K29 PolarHBondContact OD2-NZ 2.97Å; N25-K29 WeakPolarHBondContact O-CG 3.5Å; N25-K29 PolarHBondContact O-N 2.92Å; V26-K29 PolarHBondContact O-N 3.24Å; K27-K29 VanDerWaalsContact C-N 3.33Å; K27-K29 PolarHBondContact O-N 3.14Å; K29-K33 WeakPolarHBondContact O-CB 3.48Å; K29-K33 PolarHBondContact O-N 3.44Å
30I94.2Very high91.7Very high0 Ų048.5 Ų48.50%027%0.266CS..Hα-helixtrans-71.7-40.6172.4-66164.2000110.4V5 L15 V26 K27 N28 K33 E34 Q41 L43 L69V5-I30 HydrophobicContact CG1-CD1 4.24Å; V5-I30 HydrophobicContact CG2-CD1 4.24Å; L15-I30 HydrophobicContact CD1-CD1 4.15Å; L15-I30 HydrophobicContact CD1-CG1 3.54Å; V26-I30 HydrophobicContact CG1-CD1 4.36Å; V26-I30 WeakPolarHBondContact O-CG1 3.38Å; V26-I30 PolarHBondContact O-N 3.47Å; K27-I30 WeakPolarHBondContact O-CA 3.45Å; K27-I30 WeakPolarHBondContact O-CB 3.38Å; K27-I30 PolarHBondContact O-N 3.32Å; K27-I30 VanDerWaalsContact O-N 3.09Å; N28-I30 PolarHBondContact O-N 3.43Å; I30-K33 PolarHBondContact O-N 2.84Å; I30-E34 HydrophobicContact CG2-CB 4.45Å; I30-E34 WeakPolarHBondContact O-CB 3.46Å; I30-E34 PolarHBondContact O-N 3.49Å; I30-Q41 VanDerWaalsContact CD1-OE1 3.31Å; I30-Q41 HydrophobicContact CG2-CG 4.5Å; I30-L43 HydrophobicContact CD1-CD1 4.09Å; I30-L43 HydrophobicContact CD1-CD2 3.75Å; I30-L43 HydrophobicContact CD1-CG 4.41Å; I30-L69 HydrophobicContact CG2-CD2 4.22Å
31Q91.2Very high91.5Very high49 Ų4944.8 Ų44.823%0.22924%0.24CC..Hα-helixtrans-59.1-48174.8-176.7179.917.600110.9K27 N28 K33 G35 I36 E94K27-Q31 PolarHBondContact O-N 3.29Å; N28-Q31 WeakPolarHBondContact O-CA 3.47Å; N28-Q31 WeakPolarHBondContact O-CB 3.47Å; N28-Q31 PolarHBondContact O-N 3.01Å; Q31-K33 PolarHBondContact O-N 3.01Å; Q31-G35 WeakPolarHBondContact O-CA 3.27Å; Q31-G35 PolarHBondContact O-N 3.27Å; Q31-I36 VanDerWaalsContact CA-O 3.25Å; Q31-I36 WeakPolarHBondContact CA-O 3.38Å; Q31-I36 VanDerWaalsContact CB-O 3.23Å; Q31-I36 WeakPolarHBondContact CB-O 3.38Å; Q31-E94 PolarHBondContact NE2-OE1 3.41Å; Q31-E94 PolarHBondContact NE2-OE2 3.31Å
32D87.8Confident91.3Very high138 Ų13848.1 Ų48.174%0.73825%0.251SS*.Hα-helixtrans-60.7-32.6179.2-65.3-25.7000112.5N28N28-D32 PolarHBondContact O-N 2.78Å
33K88.9Confident91.2Very high119 Ų11947 Ų4752%0.51724%0.243SC..Hα-helixtrans-91.7-33.7-174.4-165.8161.7-172.7160.30114.1I13 T14 L15 K29 I30 Q31I13-K33 HydrophobicContact CG2-CD 3.97Å; I13-K33 HydrophobicContact CG2-CG 4.45Å; T14-K33 PolarHBondContact O-NZ 3.25Å; L15-K33 HydrophobicContact CD2-CD 3.93Å; K29-K33 WeakPolarHBondContact O-CB 3.48Å; K29-K33 PolarHBondContact O-N 3.44Å; I30-K33 PolarHBondContact O-N 2.84Å; Q31-K33 PolarHBondContact O-N 3.01Å
34E88.4Confident91.2Very high59 Ų5949.1 Ų49.128%0.27625%0.254SS..Hα-helixtrans-123.9-4.9-170.2-63.3-73.714500113.2K11 I13 I30 I36K11-E34 WeakPolarHBondContact CE-OE2 3.47Å; K11-E34 IonicContact NZ-OE1 2.81Å; K11-E34 PolarHBondContact NZ-OE1 3.45Å; K11-E34 IonicContact NZ-OE2 2.81Å; K11-E34 PolarHBondContact NZ-OE2 3.33Å; I13-E34 HydrophobicContact CD1-CG 3.65Å; I13-E34 HydrophobicContact CG1-CG 3.97Å; I13-E34 HydrophobicContact CG2-CG 4.16Å; I30-E34 HydrophobicContact CG2-CB 4.45Å; I30-E34 WeakPolarHBondContact O-CB 3.46Å; I30-E34 PolarHBondContact O-N 3.49Å; E34-I36 VanDerWaalsContact C-N 3.26Å; E34-I36 HydrophobicContact CB-CD1 3.93Å; E34-I36 HydrophobicContact CB-CG1 4.04Å; E34-I36 PolarHBondContact O-N 2.95Å
35G85.1Confident91.3Very high60 Ų6046.1 Ų46.162%0.61924%0.239SC*.  trans72.414.7-179.600000114.5Q31 P37Q31-G35 WeakPolarHBondContact O-CA 3.27Å; Q31-G35 PolarHBondContact O-N 3.27Å; G35-P37 WeakPolarHBondContact O-CD 3.4Å
36I85.3Confident91.2Very high28 Ų2846.7 Ų46.714%0.14425%0.254CS..  trans-93.9118.9-175.2-56.3171.1000109.3Q31 E34 Q40 Q41 L69 L71Q31-I36 VanDerWaalsContact CA-O 3.25Å; Q31-I36 WeakPolarHBondContact CA-O 3.38Å; Q31-I36 VanDerWaalsContact CB-O 3.23Å; Q31-I36 WeakPolarHBondContact CB-O 3.38Å; E34-I36 VanDerWaalsContact C-N 3.26Å; E34-I36 HydrophobicContact CB-CD1 3.93Å; E34-I36 HydrophobicContact CB-CG1 4.04Å; E34-I36 PolarHBondContact O-N 2.95Å; I36-Q40 HydrophobicContact CG2-CB 4.36Å; I36-Q41 HydrophobicContact CB-CG 4.38Å; I36-Q41 HydrophobicContact CG2-CG 3.67Å; I36-Q41 PolarHBondContact O-NE2 3.24Å; I36-L69 HydrophobicContact CD1-CD2 4.16Å; I36-L71 HydrophobicContact CD1-CD1 4.47Å; I36-L71 HydrophobicContact CD1-CD2 4.02Å; I36-L71 HydrophobicContact CG2-CD2 3.64Å
37P85.1Confident90.9Very high15 Ų1550.3 Ų50.310%0.09729%0.292CS..  trans-59.1140.2178.6-3140.2000114.4G35 D39 Q40 Q41 E94G35-P37 WeakPolarHBondContact O-CD 3.4Å; P37-D39 WeakPolarHBondContact CB-OD1 3.08Å; P37-D39 PolarHBondContact O-N 3.42Å; P37-Q40 HydrophobicContact CB-CG 4.33Å; P37-Q40 WeakPolarHBondContact O-CB 3.45Å; P37-Q40 PolarHBondContact O-N 2.91Å; P37-Q41 WeakPolarHBondContact O-CG 3.47Å; P37-Q41 PolarHBondContact O-N 2.84Å; P37-E94 WeakPolarHBondContact CB-OE1 3.43Å
38P89.3Confident90.9Very high20 Ų2056.7 Ų56.713%0.1332%0.32CS..THydrogen-bonded Turntrans-56.9-30.3-176.9-28.635.5000115.5K27 N28 Q41K27-P38 HydrophobicContact CB-CB 3.86Å; K27-P38 HydrophobicContact CB-CG 4.42Å; K27-P38 HydrophobicContact CD-CB 4.26Å; K27-P38 PolarHBondContact NZ-O 3.41Å; N28-P38 WeakPolarHBondContact OD1-CG 3.37Å; P38-Q41 PolarHBondContact O-N 3.28Å
39D85.2Confident90.9Very high55 Ų5557.9 Ų57.929%0.29432%0.323SS..THydrogen-bonded Turntrans-72.3-27.9177.764.3-19.2000113P37 Q41 G76P37-D39 WeakPolarHBondContact CB-OD1 3.08Å; P37-D39 PolarHBondContact O-N 3.42Å; D39-Q41 VanDerWaalsContact C-N 3.32Å; D39-G76 WeakPolarHBondContact OD2-CA 3.1Å; D39-G76 PolarHBondContact OD2-N 3.1Å
40Q87.1Confident90.9Very high39 Ų3954.9 Ų54.918%0.18231%0.31CS..THydrogen-bonded Turntrans-80.8-15.5171.6-63.8-175.86.500112.4I36 P37 L71 R72I36-Q40 HydrophobicContact CG2-CB 4.36Å; P37-Q40 HydrophobicContact CB-CG 4.33Å; P37-Q40 WeakPolarHBondContact O-CB 3.45Å; P37-Q40 PolarHBondContact O-N 2.91Å; Q40-L71 CarbonylContact O-C 3.47Å; Q40-L71 WeakPolarHBondContact O-CA 3.46Å; Q40-R72 PolarHBondContact O-N 3.16Å
41Q91.7Very high91Very high0 Ų059.7 Ų59.70%033%0.333CS..EExtended strand (participates in β ladder)trans-88.1130.4-178.7-62.4177.438.200112.2K27 I30 I36 P37 P38 D39 L69K27-Q41 HydrophobicContact CD-CB 4.35Å; K27-Q41 WeakPolarHBondContact CE-O 3.44Å; K27-Q41 HydrophobicContact CG-CB 4.1Å; K27-Q41 PolarHBondContact NZ-O 2.88Å; K27-Q41 VanDerWaalsContact NZ-O 3.14Å; K27-Q41 PolarHBondContact O-NE2 3.17Å; K27-Q41 PolarHBondContact O-OE1 2.73Å; I30-Q41 VanDerWaalsContact CD1-OE1 3.31Å; I30-Q41 HydrophobicContact CG2-CG 4.5Å; I36-Q41 HydrophobicContact CB-CG 4.38Å; I36-Q41 HydrophobicContact CG2-CG 3.67Å; I36-Q41 PolarHBondContact O-NE2 3.24Å; P37-Q41 WeakPolarHBondContact O-CG 3.47Å; P37-Q41 PolarHBondContact O-N 2.84Å; P38-Q41 PolarHBondContact O-N 3.28Å; D39-Q41 VanDerWaalsContact C-N 3.32Å; Q41-L69 HydrophobicContact CB-CD1 3.82Å; Q41-L69 HydrophobicContact CG-CD1 3.98Å
42R92.3Very high91Very high91 Ų9160.6 Ų60.634%0.34334%0.339SS..EExtended strand (participates in β ladder)trans-125.5108168.2-156.3180-161.1-174.91.5109Q49 V70R42-Q49 HydrophobicContact CG-CG 4.03Å; R42-V70 HydrophobicContact CB-CB 4.3Å; R42-V70 VanDerWaalsContact CB-O 3.32Å; R42-V70 WeakPolarHBondContact CB-O 3.42Å; R42-V70 PolarHBondContact N-O 2.93Å; R42-V70 PolarHBondContact O-N 2.72Å
43L95.6Very high91.2Very high1 Ų157.8 Ų57.81%0.00534%0.343CS..EExtended strand (participates in β ladder)trans-88.6134.5179.2-65.4174.7000110.5V5 I23 V26 K27 I30 L50 L67 L69V5-L43 HydrophobicContact CG1-CD2 4.08Å; I23-L43 HydrophobicContact CG2-CD1 4.26Å; V26-L43 HydrophobicContact CB-CD1 4.42Å; V26-L43 HydrophobicContact CG1-CD1 3.89Å; K27-L43 HydrophobicContact CG-CD1 3.98Å; I30-L43 HydrophobicContact CD1-CD1 4.09Å; I30-L43 HydrophobicContact CD1-CD2 3.75Å; I30-L43 HydrophobicContact CD1-CG 4.41Å; L43-L50 HydrophobicContact CB-CB 4.22Å; L43-L50 HydrophobicContact CB-CD1 3.88Å; L43-L50 HydrophobicContact CB-CG 4.24Å; L43-L50 PolarHBondContact O-N 2.89Å; L43-L67 HydrophobicContact CB-CD2 4.47Å; L43-L67 HydrophobicContact CD1-CD2 4.35Å; L43-L69 HydrophobicContact CD2-CB 4.27Å; L43-L69 HydrophobicContact CD2-CD1 3.89Å
44I96.4Very high91.6Very high45 Ų4557.4 Ų57.423%0.23134%0.338CS..EExtended strand (participates in β ladder)trans-126.9132.3179.7-57.2179.5000108.7K48 L67 H68 V70I44-K48 CarbonylContact C-O 3.59Å; I44-K48 VanDerWaalsContact CA-O 3.3Å; I44-K48 WeakPolarHBondContact CA-O 3.45Å; I44-K48 WeakPolarHBondContact CG2-O 3.36Å; I44-L67 CarbonylContact O-C 3.57Å; I44-L67 WeakPolarHBondContact O-CA 3.39Å; I44-H68 HydrophobicContact CB-CB 4.32Å; I44-H68 PolarHBondContact N-O 3.13Å; I44-H68 PolarHBondContact O-N 2.89Å; I44-V70 HydrophobicContact CD1-CG2 3.68Å; I44-V70 HydrophobicContact CG1-CG2 4.46Å
45F96.8Very high92Very high41 Ų4156.2 Ų56.218%0.1834%0.335CS..EExtended strand (participates in β ladder)trans-134.3133.4172.8-177.1-110.8000109.6G47 K48 L50 I61 L67F45-G47 PolarHBondContact O-N 3.3Å; F45-G47 VanDerWaalsContact O-N 3.13Å; F45-K48 PolarHBondContact N-O 2.81Å; F45-K48 PolarHBondContact O-N 2.87Å; F45-L50 HydrophobicContact CB-CD1 4.22Å; F45-L50 HydrophobicContact CB-CD2 3.93Å; F45-L50 HydrophobicContact CB-CG 4.35Å; F45-I61 HydrophobicContact CB-CD1 4.28Å; F45-I61 HydrophobicContact CD1-CD1 4.16Å; F45-I61 HydrophobicContact CD1-CG1 3.57Å; F45-I61 HydrophobicContact CD2-CG1 4.36Å; F45-I61 HydrophobicContact CE1-CG1 3.72Å; F45-I61 HydrophobicContact CE2-CG1 4.49Å; F45-I61 HydrophobicContact CG-CD1 4.15Å; F45-I61 HydrophobicContact CG-CG1 3.91Å; F45-I61 HydrophobicContact CZ-CG1 4.19Å; F45-L67 HydrophobicContact CB-CG 4.33Å; F45-L67 HydrophobicContact CD2-CD1 4.19Å; F45-L67 HydrophobicContact CD2-CG 4.32Å
46A93Very high92.5Very high88 Ų8853.3 Ų53.373%0.72731%0.305SS*.THydrogen-bonded Turntrans4841.6-178.700000113.9K48A46-K48 PolarHBondContact O-N 2.67Å
47G91.7Very high93Very high76 Ų7654.8 Ų54.878%0.78432%0.318SS*.THydrogen-bonded Turntrans74.9-0.9-179.300000115.6F45F45-G47 PolarHBondContact O-N 3.3Å; F45-G47 VanDerWaalsContact O-N 3.13Å
48K93.9Very high93.5Very high144 Ų14458.6 Ų58.663%0.62634%0.338SS*.EExtended strand (participates in β ladder)trans-103.7136.7177-66.3-177.11791780110.9I44 F45 A46I44-K48 CarbonylContact C-O 3.59Å; I44-K48 VanDerWaalsContact CA-O 3.3Å; I44-K48 WeakPolarHBondContact CA-O 3.45Å; I44-K48 WeakPolarHBondContact CG2-O 3.36Å; F45-K48 PolarHBondContact N-O 2.81Å; F45-K48 PolarHBondContact O-N 2.87Å; A46-K48 PolarHBondContact O-N 2.67Å
49Q94.7Very high93.8Very high81 Ų8159.3 Ų59.338%0.37934%0.338SS..EExtended strand (participates in β ladder)trans-70.8135.5168.3-179.1-175.2-16.500109.6R42R42-Q49 HydrophobicContact CG-CG 4.03Å
50L96.1Very high94.3Very high3 Ų363 Ų632%0.01636%0.358CS..PPolyproline II helixtrans-83.5133.3176-54.3-173.5000110.3I23 L43 F45 Y59 I61 L67I23-L50 HydrophobicContact CB-CB 4.48Å; I23-L50 HydrophobicContact CD1-CB 3.95Å; I23-L50 HydrophobicContact CD1-CD1 3.7Å; I23-L50 HydrophobicContact CD1-CG 4.33Å; I23-L50 HydrophobicContact CG1-CB 3.91Å; I23-L50 HydrophobicContact CG2-CB 3.75Å; L43-L50 HydrophobicContact CB-CB 4.22Å; L43-L50 HydrophobicContact CB-CD1 3.88Å; L43-L50 HydrophobicContact CB-CG 4.24Å; L43-L50 PolarHBondContact O-N 2.89Å; F45-L50 HydrophobicContact CB-CD1 4.22Å; F45-L50 HydrophobicContact CB-CD2 3.93Å; F45-L50 HydrophobicContact CB-CG 4.35Å; L50-Y59 HydrophobicContact CB-CE2 4.24Å; L50-Y59 HydrophobicContact CD2-CD1 3.64Å; L50-Y59 HydrophobicContact CD2-CD2 3.64Å; L50-Y59 HydrophobicContact CD2-CE1 3.81Å; L50-Y59 HydrophobicContact CD2-CE2 3.77Å; L50-Y59 HydrophobicContact CD2-CG 3.54Å; L50-I61 HydrophobicContact CD1-CD1 3.86Å; L50-I61 HydrophobicContact CD2-CD1 4.38Å; L50-L67 HydrophobicContact CD1-CD2 3.52Å; L50-L67 HydrophobicContact CD1-CG 4.22Å
51E94.7Very high94.7Very high102 Ų10261.5 Ų61.548%0.47735%0.351SS..PPolyproline II helixtrans-93.9132.9179.9-66.9171.2-178.200110.3I23 G53 R54 Y59I23-E51 WeakPolarHBondContact CB-O 3.46Å; I23-E51 WeakPolarHBondContact CG1-O 3.46Å; E51-G53 VanDerWaalsContact C-N 3.27Å; E51-G53 PolarHBondContact O-N 3.47Å; E51-G53 VanDerWaalsContact O-N 3.17Å; E51-R54 HydrophobicContact CB-CG 4.32Å; E51-R54 PolarHBondContact O-N 3.29Å; E51-R54 IonicContact OE1-NH2 3.1Å; E51-R54 IonicContact OE2-CZ 3.99Å; E51-R54 IonicContact OE2-NE 2.61Å; E51-R54 PolarHBondContact OE2-NE 2.6Å; E51-R54 IonicContact OE2-NH2 3.97Å; E51-R54 PolarHBondContact OE2-NH2 2.81Å; E51-Y59 WeakPolarHBondContact CB-OH 3.19Å; E51-Y59 PolarHBondContact N-OH 3.03Å
52D92.4Very high94.8Very high67 Ų6768.2 Ų68.236%0.35838%0.382SS..THydrogen-bonded Turntrans-56.6-36.2-169.6-68.6-16.8000113.9E24 K27 R54E24-D52 HydrophobicContact CB-CB 4.22Å; E24-D52 PolarHBondContact N-O 2.89Å; E24-D52 VanDerWaalsContact N-O 3.17Å; K27-D52 WeakPolarHBondContact CD-OD1 3.43Å; K27-D52 WeakPolarHBondContact CE-OD1 3.39Å; K27-D52 VanDerWaalsContact NZ-CG 3.3Å; K27-D52 IonicContact NZ-OD1 3.05Å; K27-D52 PolarHBondContact NZ-OD1 3.06Å; K27-D52 IonicContact NZ-OD2 3.96Å; K27-D52 PolarHBondContact NZ-OD2 2.96Å; K27-D52 VanDerWaalsContact NZ-OD2 3.1Å; D52-R54 PolarHBondContact O-N 2.91Å
53G92.3Very high94.9Very high79 Ų7970 Ų7081%0.81439%0.393SS*.THydrogen-bonded Turntrans-82.3-3.1-17900000116.1E51E51-G53 VanDerWaalsContact C-N 3.27Å; E51-G53 PolarHBondContact O-N 3.47Å; E51-G53 VanDerWaalsContact O-N 3.17Å
54R96.1Very high94.9Very high111 Ų11175.7 Ų75.742%0.41942%0.419SS..SBendtrans-95162.4175.3-65.4-163.4-161.1-152.8-0.4111.1S22 I23 E51 D52 D58 Y59S22-R54 CarbonylContact C-O 3.54Å; S22-R54 VanDerWaalsContact CA-O 3.28Å; S22-R54 WeakPolarHBondContact CA-O 3.42Å; I23-R54 WeakPolarHBondContact CG1-O 3.35Å; I23-R54 PolarHBondContact N-O 2.79Å; E51-R54 HydrophobicContact CB-CG 4.32Å; E51-R54 PolarHBondContact O-N 3.29Å; E51-R54 IonicContact OE1-NH2 3.1Å; E51-R54 IonicContact OE2-CZ 3.99Å; E51-R54 IonicContact OE2-NE 2.61Å; E51-R54 PolarHBondContact OE2-NE 2.6Å; E51-R54 IonicContact OE2-NH2 3.97Å; E51-R54 PolarHBondContact OE2-NH2 2.81Å; D52-R54 PolarHBondContact O-N 2.91Å; R54-D58 HydrophobicContact CB-CB 4.2Å; R54-Y59 HydrophobicContact CB-CD2 4.38Å; R54-Y59 HydrophobicContact CB-CE2 3.64Å; R54-Y59 HydrophobicContact CG-CE2 4.33Å
55T96.9Very high94.9Very high34 Ų3474.4 Ų74.421%0.20941%0.414CS..BIsolated β-bridgetrans-93.1163.8175.967.30000111.9S20 D21 S57 D58 Y59S20-T55 WeakPolarHBondContact O-CG2 3.47Å; D21-T55 CarbonylContact O-C 3.58Å; D21-T55 VanDerWaalsContact O-CA 3.28Å; D21-T55 WeakPolarHBondContact O-CA 3.46Å; T55-S57 PolarHBondContact O-N 2.95Å; T55-S57 PolarHBondContact OG1-N 2.72Å; T55-S57 PolarHBondContact OG1-OG 2.72Å; T55-D58 PolarHBondContact N-OD2 2.78Å; T55-D58 WeakPolarHBondContact O-CB 3.39Å; T55-D58 PolarHBondContact O-N 2.88Å; T55-D58 PolarHBondContact OG1-N 2.88Å; T55-D58 PolarHBondContact OG1-OD2 2.69Å; T55-Y59 WeakPolarHBondContact O-CD2 3.49Å
56L96.2Very high94.9Very high0 Ų075.1 Ų75.10%042%0.422CS..THydrogen-bonded Turntrans-57.6-36170.6-70.9176.7000112.2M1 I3 V17 D21 I23 V26 D58 Y59 N60 I61M1-L56 HydrophobicContact CE-CD1 4.2Å; I3-L56 HydrophobicContact CD1-CD1 4.49Å; V17-L56 HydrophobicContact CB-CD1 3.7Å; V17-L56 HydrophobicContact CG1-CD1 4.31Å; V17-L56 HydrophobicContact CG2-CD1 3.48Å; V17-L56 VanDerWaalsContact CG2-CD1 3.48Å; D21-L56 HydrophobicContact CB-CD1 4.25Å; D21-L56 PolarHBondContact O-N 2.79Å; I23-L56 HydrophobicContact CD1-CD2 3.82Å; I23-L56 HydrophobicContact CD1-CG 4.5Å; V26-L56 HydrophobicContact CG2-CD1 3.91Å; V26-L56 HydrophobicContact CG2-CD2 4.06Å; V26-L56 HydrophobicContact CG2-CG 4.03Å; L56-D58 VanDerWaalsContact C-N 3.35Å; L56-D58 PolarHBondContact O-N 2.74Å; L56-Y59 PolarHBondContact O-N 3.33Å; L56-N60 PolarHBondContact O-N 3.3Å; L56-I61 HydrophobicContact CB-CB 4.3Å; L56-I61 HydrophobicContact CD2-CB 4.24Å; L56-I61 HydrophobicContact CD2-CD1 3.53Å; L56-I61 HydrophobicContact CD2-CG1 4.47Å; L56-I61 HydrophobicContact CD2-CG2 4.15Å; L56-I61 PolarHBondContact O-N 3.3Å; L56-I61 VanDerWaalsContact O-N 3.13Å
57S95.1Very high95Very high59 Ų5970.9 Ų70.941%0.41339%0.387SS..G310 helixtrans-65.2-34.9178.773.80000113P19 T55 Y59 N60P19-S57 VanDerWaalsContact O-CB 3.31Å; P19-S57 WeakPolarHBondContact O-CB 3.4Å; P19-S57 PolarHBondContact O-N 2.81Å; T55-S57 PolarHBondContact O-N 2.95Å; T55-S57 PolarHBondContact OG1-N 2.72Å; T55-S57 PolarHBondContact OG1-OG 2.72Å; S57-Y59 PolarHBondContact O-N 3.14Å; S57-Y59 VanDerWaalsContact O-N 3.13Å; S57-N60 PolarHBondContact O-N 3.4Å
58D95.8Very high95.3Very high94 Ų9471.6 Ų71.650%0.50337%0.37SS..G310 helixtrans-62.3-23.1177.3-64.4-45.3000112.9R54 T55 L56R54-D58 HydrophobicContact CB-CB 4.2Å; T55-D58 PolarHBondContact N-OD2 2.78Å; T55-D58 WeakPolarHBondContact O-CB 3.39Å; T55-D58 PolarHBondContact O-N 2.88Å; T55-D58 PolarHBondContact OG1-N 2.88Å; T55-D58 PolarHBondContact OG1-OD2 2.69Å; L56-D58 VanDerWaalsContact C-N 3.35Å; L56-D58 PolarHBondContact O-N 2.74Å
59Y96Very high95.3Very high36 Ų3664.9 Ų64.914%0.14134%0.341CS..G310 helixtrans-1027.9177.2-68.4-75.4000113.6I23 L50 E51 R54 T55 L56 S57 I61I23-Y59 HydrophobicContact CD1-CD2 4.31Å; I23-Y59 HydrophobicContact CD1-CE2 4.44Å; I23-Y59 HydrophobicContact CG1-CD2 4.45Å; I23-Y59 HydrophobicContact CG1-CE2 4.11Å; L50-Y59 HydrophobicContact CB-CE2 4.24Å; L50-Y59 HydrophobicContact CD2-CD1 3.64Å; L50-Y59 HydrophobicContact CD2-CD2 3.64Å; L50-Y59 HydrophobicContact CD2-CE1 3.81Å; L50-Y59 HydrophobicContact CD2-CE2 3.77Å; L50-Y59 HydrophobicContact CD2-CG 3.54Å; E51-Y59 WeakPolarHBondContact CB-OH 3.19Å; E51-Y59 PolarHBondContact N-OH 3.03Å; R54-Y59 HydrophobicContact CB-CD2 4.38Å; R54-Y59 HydrophobicContact CB-CE2 3.64Å; R54-Y59 HydrophobicContact CG-CE2 4.33Å; T55-Y59 WeakPolarHBondContact O-CD2 3.49Å; L56-Y59 PolarHBondContact O-N 3.33Å; S57-Y59 PolarHBondContact O-N 3.14Å; S57-Y59 VanDerWaalsContact O-N 3.13Å; Y59-I61 PolarHBondContact O-N 3.17Å
60N95.5Very high95.1Very high133 Ų13363 Ų6371%0.71134%0.335SS*.THydrogen-bonded Turntrans52.736.3-174.5-71-37.8000113.2L56 S57 Q62L56-N60 PolarHBondContact O-N 3.3Å; S57-N60 PolarHBondContact O-N 3.4Å; N60-Q62 PolarHBondContact O-N 3.32Å
61I94.9Very high94.7Very high6 Ų667 Ų673%0.03136%0.356CS..PPolyproline II helixtrans-76.2118176.6-65169.1000108.2M1 I3 F45 L50 L56 Y59 L67M1-I61 WeakPolarHBondContact CE-O 3.31Å; I3-I61 HydrophobicContact CG2-CG2 4.13Å; F45-I61 HydrophobicContact CB-CD1 4.28Å; F45-I61 HydrophobicContact CD1-CD1 4.16Å; F45-I61 HydrophobicContact CD1-CG1 3.57Å; F45-I61 HydrophobicContact CD2-CG1 4.36Å; F45-I61 HydrophobicContact CE1-CG1 3.72Å; F45-I61 HydrophobicContact CE2-CG1 4.49Å; F45-I61 HydrophobicContact CG-CD1 4.15Å; F45-I61 HydrophobicContact CG-CG1 3.91Å; F45-I61 HydrophobicContact CZ-CG1 4.19Å; L50-I61 HydrophobicContact CD1-CD1 3.86Å; L50-I61 HydrophobicContact CD2-CD1 4.38Å; L56-I61 HydrophobicContact CB-CB 4.3Å; L56-I61 HydrophobicContact CD2-CB 4.24Å; L56-I61 HydrophobicContact CD2-CD1 3.53Å; L56-I61 HydrophobicContact CD2-CG1 4.47Å; L56-I61 HydrophobicContact CD2-CG2 4.15Å; L56-I61 PolarHBondContact O-N 3.3Å; L56-I61 VanDerWaalsContact O-N 3.13Å; Y59-I61 PolarHBondContact O-N 3.17Å; I61-L67 HydrophobicContact CD1-CD1 4.31Å; I61-L67 HydrophobicContact CD1-CD2 4.31Å; I61-L67 HydrophobicContact CD1-CG 4.45Å; I61-L67 HydrophobicContact CG2-CD1 3.99Å
62Q93.6Very high93.9Very high141 Ų14167 Ų6766%0.65935%0.351SS*.PPolyproline II helixtrans-103.3172.7-178.6-62.9-171.6-6.600111.9N60 E64 S65N60-Q62 PolarHBondContact O-N 3.32Å; Q62-E64 PolarHBondContact O-N 2.65Å; Q62-S65 PolarHBondContact N-OG 3.05Å; Q62-S65 WeakPolarHBondContact O-CB 3.2Å; Q62-S65 PolarHBondContact O-N 2.77Å; Q62-S65 VanDerWaalsContact O-N 3.09Å; Q62-S65 PolarHBondContact O-OG 3.25Å
63K95.4Very high92.7Very high130 Ų13071.6 Ų71.657%0.56538%0.375SS*.THydrogen-bonded Turntrans-51.3138.2170.7-164.4-158.6169.8-167.80110M1 S65M1-K63 HydrophobicContact CB-CB 4.18Å; M1-K63 HydrophobicContact CB-CG 4.11Å; M1-K63 HydrophobicContact SD-CB 4.5Å; M1-K63 PolarHBondContact SD-N 3.34Å; K63-S65 PolarHBondContact O-N 3.16Å
64E95.1Very high91.2Very high119 Ų11977.7 Ų77.756%0.55637%0.373SS*.THydrogen-bonded Turntrans678.2-179.4-57.2175.5-164.300115Q2 F4 Q62Q2-E64 PolarHBondContact O-N 3.21Å; F4-E64 HydrophobicContact CE2-CB 3.94Å; F4-E64 HydrophobicContact CE2-CG 4.14Å; Q62-E64 PolarHBondContact O-N 2.65Å
65S96.6Very high89.5Confident19 Ų1974.3 Ų74.313%0.13337%0.373CS..  trans-60.1141.4170.4-66.10000111.2F4 Q62 K63F4-S65 PolarHBondContact N-O 2.82Å; Q62-S65 PolarHBondContact N-OG 3.05Å; Q62-S65 WeakPolarHBondContact O-CB 3.2Å; Q62-S65 PolarHBondContact O-N 2.77Å; Q62-S65 VanDerWaalsContact O-N 3.09Å; Q62-S65 PolarHBondContact O-OG 3.25Å; K63-S65 PolarHBondContact O-N 3.16Å
66T96.2Very high88.3Confident55 Ų5573.2 Ų73.234%0.33737%0.368SS..EExtended strand (participates in β ladder)trans-105.6113.2175.9-57.80000110.7F4 K6F4-T66 HydrophobicContact CB-CG2 4.43Å; F4-T66 CarbonylContact O-C 3.6Å; F4-T66 WeakPolarHBondContact O-CA 3.44Å; K6-T66 HydrophobicContact CB-CG2 4.09Å; K6-T66 HydrophobicContact CD-CG2 4.33Å
67L96.8Very high87.9Confident0 Ų074.7 Ų74.70%038%0.376CS..EExtended strand (participates in β ladder)trans-87.9151.3168.7-72.468.2000109.2I3 F4 V5 K6 L43 I44 F45 L50 I61I3-L67 HydrophobicContact CD1-CD1 4.08Å; I3-L67 HydrophobicContact CD1-CD2 4.41Å; F4-L67 PolarHBondContact O-N 3.43Å; V5-L67 CarbonylContact C-O 3.54Å; V5-L67 WeakPolarHBondContact CA-O 3.08Å; V5-L67 HydrophobicContact CG2-CB 4.4Å; K6-L67 PolarHBondContact N-O 3.37Å; L43-L67 HydrophobicContact CB-CD2 4.47Å; L43-L67 HydrophobicContact CD1-CD2 4.35Å; I44-L67 CarbonylContact O-C 3.57Å; I44-L67 WeakPolarHBondContact O-CA 3.39Å; F45-L67 HydrophobicContact CB-CG 4.33Å; F45-L67 HydrophobicContact CD2-CD1 4.19Å; F45-L67 HydrophobicContact CD2-CG 4.32Å; L50-L67 HydrophobicContact CD1-CD2 3.52Å; L50-L67 HydrophobicContact CD1-CG 4.22Å; I61-L67 HydrophobicContact CD1-CD1 4.31Å; I61-L67 HydrophobicContact CD1-CD2 4.31Å; I61-L67 HydrophobicContact CD1-CG 4.45Å; I61-L67 HydrophobicContact CG2-CD1 3.99Å
68H96.8Very high87.7Confident91 Ų9173.8 Ų73.842%0.42137%0.365SS..EExtended strand (participates in β ladder)trans-105.3126.2173.1-64.972.6000109.2K6 I44K6-H68 CarbonylContact O-C 3.5Å; K6-H68 WeakPolarHBondContact O-CA 3.44Å; I44-H68 HydrophobicContact CB-CB 4.32Å; I44-H68 PolarHBondContact N-O 3.13Å; I44-H68 PolarHBondContact O-N 2.89Å
69L94.5Very high87.7Confident2 Ų269.3 Ų69.31%0.0134%0.341CS..EExtended strand (participates in β ladder)trans-95.7119.1175.2176.861.9000109.7V5 K6 T7 I13 I30 I36 Q41 L43 L71V5-L69 HydrophobicContact CG1-CB 3.55Å; V5-L69 HydrophobicContact CG1-CD2 4.34Å; V5-L69 HydrophobicContact CG1-CG 4.5Å; K6-L69 PolarHBondContact O-N 3.44Å; T7-L69 HydrophobicContact CG2-CD2 4.37Å; I13-L69 HydrophobicContact CD1-CD2 4.45Å; I30-L69 HydrophobicContact CG2-CD2 4.22Å; I36-L69 HydrophobicContact CD1-CD2 4.16Å; Q41-L69 HydrophobicContact CB-CD1 3.82Å; Q41-L69 HydrophobicContact CG-CD1 3.98Å; L43-L69 HydrophobicContact CD2-CB 4.27Å; L43-L69 HydrophobicContact CD2-CD1 3.89Å; L69-L71 HydrophobicContact CD1-CD2 4.14Å; L69-L71 HydrophobicContact CD2-CD2 3.96Å; L69-L71 HydrophobicContact CG-CD2 3.91Å
70V90.6Very high87.8Confident42 Ų4270.3 Ų70.326%0.25535%0.346SS..EExtended strand (participates in β ladder)trans-108.1124.2170.7-179.10000108.1L8 R42 I44L8-V70 HydrophobicContact CD1-CG1 4.49Å; L8-V70 HydrophobicContact CD1-CG2 4.43Å; R42-V70 HydrophobicContact CB-CB 4.3Å; R42-V70 VanDerWaalsContact CB-O 3.32Å; R42-V70 WeakPolarHBondContact CB-O 3.42Å; R42-V70 PolarHBondContact N-O 2.93Å; R42-V70 PolarHBondContact O-N 2.72Å; I44-V70 HydrophobicContact CD1-CG2 3.68Å; I44-V70 HydrophobicContact CG1-CG2 4.46Å
71L86.3Confident87.8Confident87 Ų8764 Ų6446%0.45531%0.312SS..EExtended strand (participates in β ladder)trans-88.4129.9179.7-59179000110.4I36 Q40 L69I36-L71 HydrophobicContact CD1-CD1 4.47Å; I36-L71 HydrophobicContact CD1-CD2 4.02Å; I36-L71 HydrophobicContact CG2-CD2 3.64Å; Q40-L71 CarbonylContact O-C 3.47Å; Q40-L71 WeakPolarHBondContact O-CA 3.46Å; L69-L71 HydrophobicContact CD1-CD2 4.14Å; L69-L71 HydrophobicContact CD2-CD2 3.96Å; L69-L71 HydrophobicContact CG-CD2 3.91Å
72R79.1Confident87.9Confident102 Ų10268 Ų6839%0.38533%0.33SS..  trans-84.7127.1170.7-71.5179.2153.4142.5-7.9109.1Q40 R74Q40-R72 PolarHBondContact O-N 3.16Å; R72-R74 VanDerWaalsContact C-N 3.3Å; R72-R74 PolarHBondContact O-N 2.63Å
73L67.3Low87.8Confident164 Ų16462.4 Ų62.486%0.85931%0.305SS*.SBendtrans-73.1-20.2-178.8-65.6170.2000113.8
74R61.3Low87.3Confident206 Ų20662.9 Ų62.978%0.77731%0.313SS*.SBendtrans-151.297.1-179.4-63.5-174.7-169.6-177.52.7108.5R72R72-R74 VanDerWaalsContact C-N 3.3Å; R72-R74 PolarHBondContact O-N 2.63Å
75G59.8Low86.8Confident41 Ų4163.3 Ų63.342%0.42332%0.324SS..  trans-130.9-23.4-176.300000114
76G71.8Confident86.3Confident10 Ų1064.8 Ų64.810%0.10334%0.343CS..SBendtrans-107.3-176.5-165.500000115.5D39 Q78 E92D39-G76 WeakPolarHBondContact OD2-CA 3.1Å; D39-G76 PolarHBondContact OD2-N 3.1Å; G76-Q78 PolarHBondContact O-N 2.76Å; G76-E92 WeakPolarHBondContact CA-OE2 3.41Å; G76-E92 PolarHBondContact N-OE2 2.84Å
77M87.9Confident86.2Confident31 Ų3167 Ų6715%0.15335%0.347CS..EExtended strand (participates in β ladder)trans-63.2117.6168.8167171.4154.900108.3I79 V93 P95 L132 I137 K139M77-I79 HydrophobicContact CE-CG2 3.95Å; M77-V93 WeakPolarHBondContact CB-O 3.41Å; M77-V93 HydrophobicContact CE-CG2 4.19Å; M77-V93 HydrophobicContact CG-CG2 4.09Å; M77-V93 WeakPolarHBondContact O-CG2 3.35Å; M77-V93 PolarHBondContact O-N 3.47Å; M77-P95 HydrophobicContact SD-CG 3.93Å; M77-L132 HydrophobicContact CE-CD1 4.37Å; M77-I137 HydrophobicContact CE-CG2 4.37Å; M77-I137 WeakPolarHBondContact CE-O 3.35Å; M77-K139 HydrophobicContact CG-CB 4.01Å
78Q91Very high86.1Confident41 Ų4170.1 Ų70.119%0.19237%0.367CS..EExtended strand (participates in β ladder)trans-96.5140.1175.6-70.5175.48.200109.8G76 T90 L91 E92 E140G76-Q78 PolarHBondContact O-N 2.76Å; Q78-T90 HydrophobicContact CB-CG2 4.21Å; Q78-T90 HydrophobicContact CG-CG2 4.23Å; Q78-L91 VanDerWaalsContact CA-O 3.27Å; Q78-L91 WeakPolarHBondContact CA-O 3.48Å; Q78-E92 VanDerWaalsContact CG-OE1 3.25Å; Q78-E92 WeakPolarHBondContact CG-OE1 3.42Å; Q78-E92 PolarHBondContact NE2-OE1 2.74Å; Q78-E140 PolarHBondContact O-N 3.07Å
79I95.6Very high85.9Confident0 Ų066.2 Ų66.20%035%0.349CS..EExtended strand (participates in β ladder)trans-123.6158.8166.163.3170.9000109.5M77 L91 V93 V102 L132 I137 L143M77-I79 HydrophobicContact CE-CG2 3.95Å; I79-L91 HydrophobicContact CG1-CB 4.05Å; I79-L91 PolarHBondContact N-O 3.31Å; I79-L91 PolarHBondContact O-N 3.34Å; I79-V93 HydrophobicContact CB-CG2 4.31Å; I79-V93 HydrophobicContact CD1-CG1 3.86Å; I79-V93 HydrophobicContact CD1-CG2 4.03Å; I79-V93 HydrophobicContact CG1-CG1 3.93Å; I79-V93 HydrophobicContact CG1-CG2 3.8Å; I79-V93 HydrophobicContact CG2-CG2 3.73Å; I79-V102 HydrophobicContact CD1-CG1 4.25Å; I79-L132 HydrophobicContact CD1-CD1 4.25Å; I79-I137 HydrophobicContact CG2-CG2 3.99Å; I79-L143 HydrophobicContact CD1-CD1 4.21Å; I79-L143 HydrophobicContact CD1-CD2 4.29Å
80F97.1Very high85.8Confident56 Ų5668.7 Ų68.725%0.24636%0.364CS..EExtended strand (participates in β ladder)trans-109.8135.9177.8-58-73.5000110.2T88 I89 T90 E140 S141 T142 L143F80-T88 HydrophobicContact CB-CG2 3.9Å; F80-T88 HydrophobicContact CD1-CG2 4.02Å; F80-T88 HydrophobicContact CG-CG2 4.31Å; F80-I89 CarbonylContact C-O 3.59Å; F80-I89 WeakPolarHBondContact CA-O 3.28Å; F80-T90 HydrophobicContact CD1-CG2 4.31Å; F80-T90 HydrophobicContact CE1-CG2 4.02Å; F80-E140 HydrophobicContact CE2-CB 3.92Å; F80-E140 HydrophobicContact CE2-CG 3.94Å; F80-S141 PolarHBondContact N-O 2.97Å; F80-T142 CarbonylContact O-C 3.52Å; F80-T142 VanDerWaalsContact O-CA 3.3Å; F80-T142 WeakPolarHBondContact O-CA 3.21Å; F80-L143 PolarHBondContact O-N 3.43Å
81V97Very high85.8Confident0 Ų066.8 Ų66.80%035%0.352CS..EExtended strand (participates in β ladder)trans-115.8111.7174.1-177.60000108.4T88 I89 L91 I106 L119 L143 L145V81-T88 WeakPolarHBondContact O-CA 3.35Å; V81-I89 HydrophobicContact CB-CB 4.34Å; V81-I89 PolarHBondContact N-O 3.03Å; V81-I89 PolarHBondContact O-N 3.48Å; V81-L91 HydrophobicContact CG2-CD1 3.56Å; V81-L91 HydrophobicContact CG2-CG 4.19Å; V81-I106 HydrophobicContact CG1-CD1 4.15Å; V81-I106 HydrophobicContact CG2-CD1 4.17Å; V81-L119 HydrophobicContact CG1-CD2 4.17Å; V81-L143 CarbonylContact C-O 3.5Å; V81-L143 WeakPolarHBondContact CA-O 3.41Å; V81-L143 HydrophobicContact CG2-CB 4.37Å; V81-L145 HydrophobicContact CG1-CB 3.54Å; V81-L145 HydrophobicContact CG1-CD2 4.47Å
82K96.2Very high85.9Confident90 Ų9064.1 Ų64.139%0.39134%0.337SS..EExtended strand (participates in β ladder)trans-91.9127.7176.5-102.1-177.8177.4175.60111.2K87 T88 T142 L143 H144 L145K82-K87 CarbonylContact C-O 3.56Å; K82-K87 WeakPolarHBondContact CA-O 3.18Å; K82-T88 WeakPolarHBondContact CE-OG1 3.15Å; K82-T88 HydrophobicContact CG-CG2 4.31Å; K82-T88 VanDerWaalsContact CG-OG1 3.28Å; K82-T88 WeakPolarHBondContact CG-OG1 3.47Å; K82-T142 HydrophobicContact CB-CG2 4.21Å; K82-T142 HydrophobicContact CD-CG2 4.21Å; K82-T142 HydrophobicContact CG-CG2 4.31Å; K82-L143 PolarHBondContact N-O 3.29Å; K82-H144 CarbonylContact O-C 3.56Å; K82-H144 WeakPolarHBondContact O-CA 3.46Å; K82-L145 PolarHBondContact O-N 3.43Å
83T91.5Very high86.5Confident24 Ų2459.5 Ų59.515%0.14732%0.321CS..EExtended strand (participates in β ladder)trans-81.7163.3171.4710000110.8T85 G86 K87 I89 L145T83-T85 PolarHBondContact O-N 3.24Å; T83-T85 PolarHBondContact OG1-N 3.24Å; T83-T85 PolarHBondContact OG1-OG1 3.14Å; T83-G86 PolarHBondContact O-N 3.13Å; T83-K87 HydrophobicContact CG2-CB 4.19Å; T83-K87 PolarHBondContact N-O 3.13Å; T83-K87 WeakPolarHBondContact OG1-CB 3.45Å; T83-K87 PolarHBondContact OG1-N 3.48Å; T83-K87 VanDerWaalsContact OG1-N 3.14Å; T83-K87 PolarHBondContact OG1-O 3.15Å; T83-I89 HydrophobicContact CG2-CD1 4.04Å; T83-L145 HydrophobicContact CG2-CD2 4.44Å
84L85.6Confident87.5Confident141 Ų14153.4 Ų53.474%0.73829%0.288SS*.THydrogen-bonded Turntrans-62-20.3171.7-68.7177.4000113.8G86 V146L84-G86 VanDerWaalsContact C-N 3.26Å; L84-V146 HydrophobicContact CD1-CG1 4.17Å; L84-V146 HydrophobicContact CD1-CG2 4.4Å; L84-V146 HydrophobicContact CD2-CG2 4.24Å; L84-V146 HydrophobicContact CG-CG2 4.36Å
85T84.5Confident89Confident128 Ų12846.9 Ų46.979%0.78527%0.272SS*.THydrogen-bonded Turntrans-82.4-3175.358.80000113T83T83-T85 PolarHBondContact O-N 3.24Å; T83-T85 PolarHBondContact OG1-N 3.24Å; T83-T85 PolarHBondContact OG1-OG1 3.14Å
86G85.7Confident90.5Very high50 Ų5048.3 Ų48.352%0.51528%0.276SS..SBendtrans88-3.9-17800000114.7T83 L84T83-G86 PolarHBondContact O-N 3.13Å; L84-G86 VanDerWaalsContact C-N 3.26Å
87K93.7Very high91.5Very high101 Ų10148.5 Ų48.544%0.43927%0.274SS..  trans-64.2136.2173.4-175.3179.9174.7-174.20109.3K82 T83 E110K82-K87 CarbonylContact C-O 3.56Å; K82-K87 WeakPolarHBondContact CA-O 3.18Å; T83-K87 HydrophobicContact CG2-CB 4.19Å; T83-K87 PolarHBondContact N-O 3.13Å; T83-K87 WeakPolarHBondContact OG1-CB 3.45Å; T83-K87 PolarHBondContact OG1-N 3.48Å; T83-K87 VanDerWaalsContact OG1-N 3.14Å; T83-K87 PolarHBondContact OG1-O 3.15Å; K87-E110 WeakPolarHBondContact CE-OE1 3.13Å; K87-E110 IonicContact NZ-OE1 2.68Å; K87-E110 PolarHBondContact NZ-OE1 2.69Å; K87-E110 IonicContact NZ-OE2 3.19Å; K87-E110 PolarHBondContact NZ-OE2 3.11Å
88T94Very high91.8Very high66 Ų6648.6 Ų48.641%0.40528%0.277SS..EExtended strand (participates in β ladder)trans-113.7124.8177.1-55.60000109.3F80 V81 K82F80-T88 HydrophobicContact CB-CG2 3.9Å; F80-T88 HydrophobicContact CD1-CG2 4.02Å; F80-T88 HydrophobicContact CG-CG2 4.31Å; V81-T88 WeakPolarHBondContact O-CA 3.35Å; K82-T88 WeakPolarHBondContact CE-OG1 3.15Å; K82-T88 HydrophobicContact CG-CG2 4.31Å; K82-T88 VanDerWaalsContact CG-OG1 3.28Å; K82-T88 WeakPolarHBondContact CG-OG1 3.47Å
89I92.7Very high91.9Very high8 Ų846.7 Ų46.74%0.04127%0.268CS..EExtended strand (participates in β ladder)trans-106.8128.4179.3-55.5149.6000107.6F80 V81 T83 L91 K109 E110F80-I89 CarbonylContact C-O 3.59Å; F80-I89 WeakPolarHBondContact CA-O 3.28Å; V81-I89 HydrophobicContact CB-CB 4.34Å; V81-I89 PolarHBondContact N-O 3.03Å; V81-I89 PolarHBondContact O-N 3.48Å; T83-I89 HydrophobicContact CG2-CD1 4.04Å; I89-L91 HydrophobicContact CG2-CD2 4Å; I89-L91 HydrophobicContact CG2-CG 4.47Å; I89-K109 HydrophobicContact CG2-CD 4.17Å; I89-E110 HydrophobicContact CD1-CG 3.58Å; I89-E110 HydrophobicContact CG1-CG 4.02Å
90T93.3Very high91.6Very high54 Ų5452.2 Ų52.233%0.33129%0.294SS..EExtended strand (participates in β ladder)trans-92.3127.1174.4-51.20000109.6Q78 F80 K109Q78-T90 HydrophobicContact CB-CG2 4.21Å; Q78-T90 HydrophobicContact CG-CG2 4.23Å; F80-T90 HydrophobicContact CD1-CG2 4.31Å; F80-T90 HydrophobicContact CE1-CG2 4.02Å; T90-K109 PolarHBondContact O-NZ 2.92Å
91L91.1Very high91.3Very high2 Ų253 Ų531%0.0130%0.3CS..EExtended strand (participates in β ladder)trans-116.1140.6175.9-59.4177.8000110.5Q78 I79 V81 I89 V93 V102 K105 I106 K109Q78-L91 VanDerWaalsContact CA-O 3.27Å; Q78-L91 WeakPolarHBondContact CA-O 3.48Å; I79-L91 HydrophobicContact CG1-CB 4.05Å; I79-L91 PolarHBondContact N-O 3.31Å; I79-L91 PolarHBondContact O-N 3.34Å; V81-L91 HydrophobicContact CG2-CD1 3.56Å; V81-L91 HydrophobicContact CG2-CG 4.19Å; I89-L91 HydrophobicContact CG2-CD2 4Å; I89-L91 HydrophobicContact CG2-CG 4.47Å; L91-V93 HydrophobicContact CB-CG1 4.05Å; L91-V102 HydrophobicContact CD1-CG1 3.89Å; L91-K105 HydrophobicContact CD2-CB 4.32Å; L91-I106 HydrophobicContact CD1-CD1 4.12Å; L91-I106 HydrophobicContact CD1-CG1 3.56Å; L91-I106 HydrophobicContact CD2-CG1 4.39Å; L91-K109 HydrophobicContact CD2-CD 3.93Å
92E88.5Confident91.2Very high31 Ų3153 Ų5315%0.14530%0.3CS..EExtended strand (participates in β ladder)trans-91.8121.4168.3-63-78.6157.100107.8G76 Q78 K105G76-E92 WeakPolarHBondContact CA-OE2 3.41Å; G76-E92 PolarHBondContact N-OE2 2.84Å; Q78-E92 VanDerWaalsContact CG-OE1 3.25Å; Q78-E92 WeakPolarHBondContact CG-OE1 3.42Å; Q78-E92 PolarHBondContact NE2-OE1 2.74Å; E92-K105 PolarHBondContact O-NZ 3.24Å
93V90.8Very high91.1Very high5 Ų549 Ų493%0.0328%0.283CS..EExtended strand (participates in β ladder)trans-138.4158.5-172.2-62.50000111.2M77 I79 L91 D97 V102 K105 L132M77-V93 WeakPolarHBondContact CB-O 3.41Å; M77-V93 HydrophobicContact CE-CG2 4.19Å; M77-V93 HydrophobicContact CG-CG2 4.09Å; M77-V93 WeakPolarHBondContact O-CG2 3.35Å; M77-V93 PolarHBondContact O-N 3.47Å; I79-V93 HydrophobicContact CB-CG2 4.31Å; I79-V93 HydrophobicContact CD1-CG1 3.86Å; I79-V93 HydrophobicContact CD1-CG2 4.03Å; I79-V93 HydrophobicContact CG1-CG1 3.93Å; I79-V93 HydrophobicContact CG1-CG2 3.8Å; I79-V93 HydrophobicContact CG2-CG2 3.73Å; L91-V93 HydrophobicContact CB-CG1 4.05Å; V93-D97 VanDerWaalsContact CA-OD2 3.28Å; V93-D97 WeakPolarHBondContact CA-OD2 3.44Å; V93-V102 HydrophobicContact CG1-CG2 4.25Å; V93-K105 HydrophobicContact CG1-CD 4.24Å; V93-L132 HydrophobicContact CB-CD1 3.61Å; V93-L132 HydrophobicContact CG1-CD1 4.14Å; V93-L132 HydrophobicContact CG2-CD1 3.47Å; V93-L132 VanDerWaalsContact CG2-CD1 3.47Å
94E89.5Confident90.9Very high37 Ų3749.7 Ų49.717%0.17329%0.291CS..  trans-104.6150.9168.4-65.8179.4173.300110.2Q31 P37 S96 D97Q31-E94 PolarHBondContact NE2-OE1 3.41Å; Q31-E94 PolarHBondContact NE2-OE2 3.31Å; P37-E94 WeakPolarHBondContact CB-OE1 3.43Å; E94-S96 WeakPolarHBondContact CB-OG 3.24Å; E94-S96 PolarHBondContact O-N 3.42Å; E94-S96 VanDerWaalsContact O-N 3.09Å; E94-S96 PolarHBondContact OE2-OG 3.09Å; E94-D97 PolarHBondContact N-OD2 3.4Å; E94-D97 VanDerWaalsContact O-CB 3.32Å; E94-D97 WeakPolarHBondContact O-CB 3.3Å; E94-D97 PolarHBondContact O-N 3.5Å
95P91.8Very high91.2Very high69 Ų6945.4 Ų45.445%0.44827%0.266SS..THydrogen-bonded Turntrans-56.3-26.4174.1-24.633.4000113.8M77 S133M77-P95 HydrophobicContact SD-CG 3.93Å; P95-S133 WeakPolarHBondContact O-CB 3.5Å; P95-S133 PolarHBondContact O-N 3.21Å; P95-S133 PolarHBondContact O-OG 3.01Å
96S91.9Very high91.6Very high71 Ų7139.3 Ų39.350%0.49723%0.229SC..THydrogen-bonded Turntrans-79-12.5175.3360000114.3E94 T98 T131E94-S96 WeakPolarHBondContact CB-OG 3.24Å; E94-S96 PolarHBondContact O-N 3.42Å; E94-S96 VanDerWaalsContact O-N 3.09Å; E94-S96 PolarHBondContact OE2-OG 3.09Å; S96-T98 PolarHBondContact O-N 2.85Å; S96-T131 WeakPolarHBondContact O-CG2 3.38Å
97D92.3Very high91.8Very high13 Ų1340.1 Ų40.17%0.0722%0.219CC..  trans-60.2130.3179-87.3-34000110.1V93 E94 N101 V102 K105 T131 L132V93-D97 VanDerWaalsContact CA-OD2 3.28Å; V93-D97 WeakPolarHBondContact CA-OD2 3.44Å; E94-D97 PolarHBondContact N-OD2 3.4Å; E94-D97 VanDerWaalsContact O-CB 3.32Å; E94-D97 WeakPolarHBondContact O-CB 3.3Å; E94-D97 PolarHBondContact O-N 3.5Å; D97-N101 HydrophobicContact CB-CB 4.27Å; D97-N101 PolarHBondContact OD1-ND2 2.87Å; D97-V102 HydrophobicContact CB-CG2 4.25Å; D97-K105 VanDerWaalsContact OD2-CE 3.28Å; D97-K105 WeakPolarHBondContact OD2-CE 3.41Å; D97-K105 IonicContact OD2-NZ 3.34Å; D97-K105 PolarHBondContact OD2-NZ 2.71Å; D97-T131 CarbonylContact O-C 3.58Å; D97-T131 WeakPolarHBondContact O-CA 3.19Å; D97-L132 HydrophobicContact CB-CD1 4.29Å; D97-L132 HydrophobicContact CB-CG 4.45Å; D97-L132 PolarHBondContact O-N 2.91Å
98T94.1Very high91.4Very high34 Ų3441.7 Ų41.721%0.20923%0.232CC..BIsolated β-bridgetrans-71158169.8630000110.4S96 E100 N101 V102 R130S96-T98 PolarHBondContact O-N 2.85Å; T98-E100 PolarHBondContact O-N 3.14Å; T98-N101 WeakPolarHBondContact O-CB 3.29Å; T98-N101 PolarHBondContact O-N 2.89Å; T98-N101 VanDerWaalsContact O-N 3.1Å; T98-N101 PolarHBondContact OG1-N 2.94Å; T98-N101 VanDerWaalsContact OG1-N 3.11Å; T98-N101 PolarHBondContact OG1-OD1 2.94Å; T98-N101 VanDerWaalsContact OG1-OD1 3.13Å; T98-V102 WeakPolarHBondContact O-CG2 3.45Å; T98-V102 PolarHBondContact O-N 2.71Å; T98-R130 CarbonylContact C-O 3.45Å; T98-R130 VanDerWaalsContact CA-O 3.32Å; T98-R130 WeakPolarHBondContact CA-O 3.43Å
99V93.3Very high91Very high1 Ų144.3 Ų44.31%0.00624%0.238CC..Hα-helixtrans-60-32.3173.81720000110.9V102 K103 L119 L126 E127 D128 R130 Y135V99-V102 PolarHBondContact O-N 3.03Å; V99-K103 WeakPolarHBondContact O-CG 3.44Å; V99-K103 PolarHBondContact O-N 3.2Å; V99-L119 HydrophobicContact CG1-CD1 4.28Å; V99-L126 HydrophobicContact CB-CB 4.43Å; V99-L126 HydrophobicContact CG1-CB 3.8Å; V99-L126 HydrophobicContact CG2-CB 3.72Å; V99-L126 HydrophobicContact CG2-CD1 4.15Å; V99-E127 WeakPolarHBondContact CB-O 2.83Å; V99-E127 WeakPolarHBondContact CG2-O 3.25Å; V99-D128 PolarHBondContact N-O 3.43Å; V99-R130 WeakPolarHBondContact CG2-O 3.32Å; V99-R130 PolarHBondContact N-O 3.32Å; V99-Y135 HydrophobicContact CG2-CD2 4.48Å; V99-Y135 HydrophobicContact CG2-CE2 4.16Å
100E89.9Confident90.9Very high115 Ų11547 Ų4754%0.53725%0.25SS..Hα-helixtrans-61.8-46.8171.1-169.5170.5-161.700112.7T98 V102 K103 A104 D128T98-E100 PolarHBondContact O-N 3.14Å; E100-V102 VanDerWaalsContact C-N 3.27Å; E100-V102 PolarHBondContact O-N 3.29Å; E100-K103 WeakPolarHBondContact O-CB 3.43Å; E100-K103 PolarHBondContact O-N 2.82Å; E100-K103 VanDerWaalsContact O-N 3.1Å; E100-A104 PolarHBondContact O-N 2.79Å; E100-D128 HydrophobicContact CB-CB 4.28Å; E100-D128 PolarHBondContact N-O 3.19Å; E100-D128 VanDerWaalsContact N-O 3.12Å
101N91.2Very high90.5Very high72 Ų7247.2 Ų47.239%0.38526%0.264SS..Hα-helixtrans-57.8-42.1173.9-67.8-0.9000111.3D97 T98 K103 A104 K105D97-N101 HydrophobicContact CB-CB 4.27Å; D97-N101 PolarHBondContact OD1-ND2 2.87Å; T98-N101 WeakPolarHBondContact O-CB 3.29Å; T98-N101 PolarHBondContact O-N 2.89Å; T98-N101 VanDerWaalsContact O-N 3.1Å; T98-N101 PolarHBondContact OG1-N 2.94Å; T98-N101 VanDerWaalsContact OG1-N 3.11Å; T98-N101 PolarHBondContact OG1-OD1 2.94Å; T98-N101 VanDerWaalsContact OG1-OD1 3.13Å; N101-K103 VanDerWaalsContact C-N 3.32Å; N101-K103 PolarHBondContact O-N 3.48Å; N101-A104 PolarHBondContact O-N 2.82Å; N101-K105 WeakPolarHBondContact O-CG 3.49Å; N101-K105 PolarHBondContact O-N 2.98Å
102V94.6Very high90.1Very high1 Ų148.4 Ų48.41%0.00627%0.27CS..Hα-helixtrans-63.6-39.9178.1177.60000111I79 L91 V93 D97 T98 V99 E100 K105 I106 L119 L132I79-V102 HydrophobicContact CD1-CG1 4.25Å; L91-V102 HydrophobicContact CD1-CG1 3.89Å; V93-V102 HydrophobicContact CG1-CG2 4.25Å; D97-V102 HydrophobicContact CB-CG2 4.25Å; T98-V102 WeakPolarHBondContact O-CG2 3.45Å; T98-V102 PolarHBondContact O-N 2.71Å; V99-V102 PolarHBondContact O-N 3.03Å; E100-V102 VanDerWaalsContact C-N 3.27Å; E100-V102 PolarHBondContact O-N 3.29Å; V102-K105 PolarHBondContact O-N 3.46Å; V102-I106 HydrophobicContact CG1-CD1 4.32Å; V102-I106 WeakPolarHBondContact O-CG1 3.35Å; V102-I106 PolarHBondContact O-N 3.25Å; V102-L119 HydrophobicContact CB-CD1 4.34Å; V102-L119 HydrophobicContact CG1-CD1 3.8Å; V102-L132 HydrophobicContact CG2-CD1 4.09Å; V102-L132 HydrophobicContact CG2-CD2 3.99Å; V102-L132 HydrophobicContact CG2-CG 4.13Å
103K93Very high89.8Confident7 Ų748.3 Ų48.33%0.0327%0.272CS..Hα-helixtrans-64.5-41.4175.4-72.3172.7166.2-170.60112.5V99 E100 N101 K105 I106 Q107 P114 Q117 L119 D128V99-K103 WeakPolarHBondContact O-CG 3.44Å; V99-K103 PolarHBondContact O-N 3.2Å; E100-K103 WeakPolarHBondContact O-CB 3.43Å; E100-K103 PolarHBondContact O-N 2.82Å; E100-K103 VanDerWaalsContact O-N 3.1Å; N101-K103 VanDerWaalsContact C-N 3.32Å; N101-K103 PolarHBondContact O-N 3.48Å; K103-K105 VanDerWaalsContact C-N 3.34Å; K103-K105 PolarHBondContact O-N 3.38Å; K103-I106 WeakPolarHBondContact O-CB 3.23Å; K103-I106 PolarHBondContact O-N 2.75Å; K103-I106 VanDerWaalsContact O-N 3.14Å; K103-Q107 PolarHBondContact O-N 3.16Å; K103-P114 HydrophobicContact CB-CB 3.86Å; K103-P114 HydrophobicContact CB-CG 4.35Å; K103-P114 HydrophobicContact CD-CB 4.17Å; K103-P114 WeakPolarHBondContact CD-O 3.36Å; K103-P114 PolarHBondContact NZ-O 2.73Å; K103-Q117 HydrophobicContact CD-CB 4.4Å; K103-Q117 WeakPolarHBondContact CE-O 3.18Å; K103-Q117 HydrophobicContact CG-CB 4.09Å; K103-Q117 PolarHBondContact NZ-O 2.83Å; K103-Q117 PolarHBondContact O-NE2 2.81Å; K103-Q117 PolarHBondContact O-OE1 3.34Å; K103-L119 HydrophobicContact CG-CD1 3.96Å; K103-L119 HydrophobicContact CG-CG 4.49Å; K103-D128 WeakPolarHBondContact CE-OD1 3.47Å; K103-D128 IonicContact NZ-OD1 2.6Å; K103-D128 PolarHBondContact NZ-OD1 2.74Å; K103-D128 IonicContact NZ-OD2 2.81Å; K103-D128 PolarHBondContact NZ-OD2 3.09Å
104A88.1Confident89.4Confident37 Ų3748.8 Ų48.831%0.30628%0.276SS..Hα-helixtrans-59-45.2173.500000111.1E100 N101 I106 Q107 D108E100-A104 PolarHBondContact O-N 2.79Å; N101-A104 PolarHBondContact O-N 2.82Å; A104-I106 VanDerWaalsContact C-N 3.25Å; A104-I106 PolarHBondContact O-N 3.31Å; A104-Q107 WeakPolarHBondContact O-CA 3.38Å; A104-Q107 VanDerWaalsContact O-CB 3.29Å; A104-Q107 WeakPolarHBondContact O-CB 3.35Å; A104-Q107 PolarHBondContact O-N 2.99Å; A104-D108 PolarHBondContact O-N 3.44Å
105K92.2Very high88.8Confident52 Ų5249 Ų4923%0.22628%0.278CS..Hα-helixtrans-61.3-31.2175.3-66.7173.4-167.7-121.70113.3L91 E92 V93 D97 N101 V102 K103 K109L91-K105 HydrophobicContact CD2-CB 4.32Å; E92-K105 PolarHBondContact O-NZ 3.24Å; V93-K105 HydrophobicContact CG1-CD 4.24Å; D97-K105 VanDerWaalsContact OD2-CE 3.28Å; D97-K105 WeakPolarHBondContact OD2-CE 3.41Å; D97-K105 IonicContact OD2-NZ 3.34Å; D97-K105 PolarHBondContact OD2-NZ 2.71Å; N101-K105 WeakPolarHBondContact O-CG 3.49Å; N101-K105 PolarHBondContact O-N 2.98Å; V102-K105 PolarHBondContact O-N 3.46Å; K103-K105 VanDerWaalsContact C-N 3.34Å; K103-K105 PolarHBondContact O-N 3.38Å; K105-K109 PolarHBondContact O-N 2.96Å
106I93.1Very high88.4Confident0 Ų047.8 Ų47.80%027%0.266CS..Hα-helixtrans-71.8-41.3173-66.9164.6000110.5V81 L91 V102 K103 A104 D108 K109 E110 Q117 L119 L145V81-I106 HydrophobicContact CG1-CD1 4.15Å; V81-I106 HydrophobicContact CG2-CD1 4.17Å; L91-I106 HydrophobicContact CD1-CD1 4.12Å; L91-I106 HydrophobicContact CD1-CG1 3.56Å; L91-I106 HydrophobicContact CD2-CG1 4.39Å; V102-I106 HydrophobicContact CG1-CD1 4.32Å; V102-I106 WeakPolarHBondContact O-CG1 3.35Å; V102-I106 PolarHBondContact O-N 3.25Å; K103-I106 WeakPolarHBondContact O-CB 3.23Å; K103-I106 PolarHBondContact O-N 2.75Å; K103-I106 VanDerWaalsContact O-N 3.14Å; A104-I106 VanDerWaalsContact C-N 3.25Å; A104-I106 PolarHBondContact O-N 3.31Å; I106-D108 VanDerWaalsContact C-N 3.33Å; I106-D108 PolarHBondContact O-N 2.68Å; I106-K109 PolarHBondContact O-N 2.86Å; I106-E110 WeakPolarHBondContact O-CB 3.31Å; I106-E110 PolarHBondContact O-N 3.45Å; I106-Q117 VanDerWaalsContact CD1-OE1 3.29Å; I106-L119 HydrophobicContact CD1-CD1 4.04Å; I106-L119 HydrophobicContact CD1-CD2 3.68Å; I106-L119 HydrophobicContact CD1-CG 4.37Å; I106-L145 HydrophobicContact CG2-CD2 4.11Å
107Q88.8Confident88.3Confident67 Ų6744.4 Ų44.431%0.31324%0.243SC..Hα-helixtrans-58.9-46.1174.8-176.9-176.212.600110.8K103 A104 K109 G111 I112 P114K103-Q107 PolarHBondContact O-N 3.16Å; A104-Q107 WeakPolarHBondContact O-CA 3.38Å; A104-Q107 VanDerWaalsContact O-CB 3.29Å; A104-Q107 WeakPolarHBondContact O-CB 3.35Å; A104-Q107 PolarHBondContact O-N 2.99Å; Q107-K109 VanDerWaalsContact C-N 3.25Å; Q107-K109 PolarHBondContact O-N 2.99Å; Q107-G111 WeakPolarHBondContact O-CA 3.25Å; Q107-G111 PolarHBondContact O-N 2.88Å; Q107-I112 VanDerWaalsContact CA-O 3.29Å; Q107-I112 WeakPolarHBondContact CA-O 3.28Å; Q107-I112 VanDerWaalsContact CB-O 3.24Å; Q107-I112 WeakPolarHBondContact CB-O 3.41Å; Q107-P114 VanDerWaalsContact OE1-CD 3.24Å
108D84.4Confident88.2Confident133 Ų13348.5 Ų48.571%0.71126%0.257SS*.Hα-helixtrans-60.5-35.1179-66.1-24000112.5A104 I106A104-D108 PolarHBondContact O-N 3.44Å; I106-D108 VanDerWaalsContact C-N 3.33Å; I106-D108 PolarHBondContact O-N 2.68Å
109K87.2Confident88.2Confident122 Ų12247 Ų4753%0.5325%0.247SC..Hα-helixtrans-86.9-35.8-178.8-75.5-157.2179.1-167.90114.8I89 T90 L91 K105 I106 Q107I89-K109 HydrophobicContact CG2-CD 4.17Å; T90-K109 PolarHBondContact O-NZ 2.92Å; L91-K109 HydrophobicContact CD2-CD 3.93Å; K105-K109 PolarHBondContact O-N 2.96Å; I106-K109 PolarHBondContact O-N 2.86Å; Q107-K109 VanDerWaalsContact C-N 3.25Å; Q107-K109 PolarHBondContact O-N 2.99Å
110E89.7Confident88.4Confident63 Ų6348.8 Ų48.829%0.29426%0.257SS..Hα-helixtrans-120.6-5.3-168.2-64-71.6143.400113.2K87 I89 I106 I112K87-E110 WeakPolarHBondContact CE-OE1 3.13Å; K87-E110 IonicContact NZ-OE1 2.68Å; K87-E110 PolarHBondContact NZ-OE1 2.69Å; K87-E110 IonicContact NZ-OE2 3.19Å; K87-E110 PolarHBondContact NZ-OE2 3.11Å; I89-E110 HydrophobicContact CD1-CG 3.58Å; I89-E110 HydrophobicContact CG1-CG 4.02Å; I106-E110 WeakPolarHBondContact O-CB 3.31Å; I106-E110 PolarHBondContact O-N 3.45Å; E110-I112 HydrophobicContact CB-CD1 3.87Å; E110-I112 HydrophobicContact CB-CG1 3.9Å; E110-I112 PolarHBondContact O-N 3.17Å
111G84.1Confident88.7Confident60 Ų6045.3 Ų45.362%0.61924%0.24SC*.  trans70.514.3-177.700000114.3Q107 P113Q107-G111 WeakPolarHBondContact O-CA 3.25Å; Q107-G111 PolarHBondContact O-N 2.88Å; G111-P113 WeakPolarHBondContact O-CD 2.88Å
112I83.8Confident88.8Confident26 Ų2646.4 Ų46.413%0.13326%0.259CS..  trans-90.6118.1-175.6-55.4174.6000109.4Q107 E110 Q116 Q117 L145 L147Q107-I112 VanDerWaalsContact CA-O 3.29Å; Q107-I112 WeakPolarHBondContact CA-O 3.28Å; Q107-I112 VanDerWaalsContact CB-O 3.24Å; Q107-I112 WeakPolarHBondContact CB-O 3.41Å; E110-I112 HydrophobicContact CB-CD1 3.87Å; E110-I112 HydrophobicContact CB-CG1 3.9Å; E110-I112 PolarHBondContact O-N 3.17Å; I112-Q116 HydrophobicContact CG2-CB 4.31Å; I112-Q117 HydrophobicContact CB-CG 4.46Å; I112-Q117 HydrophobicContact CG2-CG 3.75Å; I112-Q117 PolarHBondContact O-NE2 2.9Å; I112-L145 HydrophobicContact CD1-CD2 4.04Å; I112-L147 HydrophobicContact CD1-CD2 4.05Å; I112-L147 HydrophobicContact CG2-CD2 3.61Å
113P80.9Confident88.5Confident29 Ų2950 Ų5019%0.18830%0.296CS..  trans-60.9140.5-179.8-26.536.7000113.9G111 D115 Q116 Q117G111-P113 WeakPolarHBondContact O-CD 2.88Å; P113-D115 VanDerWaalsContact C-N 3.27Å; P113-D115 VanDerWaalsContact CB-OD1 3.27Å; P113-D115 WeakPolarHBondContact CB-OD1 3.03Å; P113-D115 PolarHBondContact O-N 3.46Å; P113-Q116 HydrophobicContact CB-CG 4.36Å; P113-Q116 WeakPolarHBondContact O-CB 3.36Å; P113-Q116 PolarHBondContact O-N 3Å; P113-Q116 VanDerWaalsContact O-N 3.08Å; P113-Q117 WeakPolarHBondContact O-CG 3.49Å; P113-Q117 PolarHBondContact O-N 2.79Å
114P84.2Confident88.5Confident16 Ų1655 Ų5510%0.10432%0.318CS..THydrogen-bonded Turntrans-53.5-33.3-177.1-31.437.1000116K103 Q107 Q117 E170K103-P114 HydrophobicContact CB-CB 3.86Å; K103-P114 HydrophobicContact CB-CG 4.35Å; K103-P114 HydrophobicContact CD-CB 4.17Å; K103-P114 WeakPolarHBondContact CD-O 3.36Å; K103-P114 PolarHBondContact NZ-O 2.73Å; Q107-P114 VanDerWaalsContact OE1-CD 3.24Å; P114-Q117 WeakPolarHBondContact O-CB 2.97Å; P114-Q117 PolarHBondContact O-N 3.23Å; P114-Q117 VanDerWaalsContact O-N 3.16Å; P114-E170 WeakPolarHBondContact CD-OE1 3.44Å
115D75.8Confident88.7Confident42 Ų4256.7 Ų56.723%0.22532%0.319CS..THydrogen-bonded Turntrans-70-31.5178.860.6-3000113.4P113 Q117 G152P113-D115 VanDerWaalsContact C-N 3.27Å; P113-D115 VanDerWaalsContact CB-OD1 3.27Å; P113-D115 WeakPolarHBondContact CB-OD1 3.03Å; P113-D115 PolarHBondContact O-N 3.46Å; D115-Q117 PolarHBondContact O-N 3.44Å; D115-G152 WeakPolarHBondContact OD2-CA 3.29Å
116Q83.2Confident88.7Confident43 Ų4354.3 Ų54.320%0.20131%0.309CS..THydrogen-bonded Turntrans-74.3-18.1171.5-61.8-169.7-2.900112.1I112 P113 L147 R148 E168I112-Q116 HydrophobicContact CG2-CB 4.31Å; P113-Q116 HydrophobicContact CB-CG 4.36Å; P113-Q116 WeakPolarHBondContact O-CB 3.36Å; P113-Q116 PolarHBondContact O-N 3Å; P113-Q116 VanDerWaalsContact O-N 3.08Å; Q116-L147 CarbonylContact O-C 3.49Å; Q116-L147 WeakPolarHBondContact O-CA 3.45Å; Q116-R148 PolarHBondContact O-N 3.2Å; Q116-E168 PolarHBondContact NE2-OE2 2.91Å
117Q89.6Confident88.5Confident0 Ų058.9 Ų58.90%033%0.331CS..EExtended strand (participates in β ladder)trans-85.3127.3-176.8-59.8178.236.100112K103 I106 I112 P113 P114 D115 L145 R148K103-Q117 HydrophobicContact CD-CB 4.4Å; K103-Q117 WeakPolarHBondContact CE-O 3.18Å; K103-Q117 HydrophobicContact CG-CB 4.09Å; K103-Q117 PolarHBondContact NZ-O 2.83Å; K103-Q117 PolarHBondContact O-NE2 2.81Å; K103-Q117 PolarHBondContact O-OE1 3.34Å; I106-Q117 VanDerWaalsContact CD1-OE1 3.29Å; I112-Q117 HydrophobicContact CB-CG 4.46Å; I112-Q117 HydrophobicContact CG2-CG 3.75Å; I112-Q117 PolarHBondContact O-NE2 2.9Å; P113-Q117 WeakPolarHBondContact O-CG 3.49Å; P113-Q117 PolarHBondContact O-N 2.79Å; P114-Q117 WeakPolarHBondContact O-CB 2.97Å; P114-Q117 PolarHBondContact O-N 3.23Å; P114-Q117 VanDerWaalsContact O-N 3.16Å; D115-Q117 PolarHBondContact O-N 3.44Å; Q117-L145 HydrophobicContact CB-CD1 3.74Å; Q117-L145 HydrophobicContact CG-CD1 3.91Å; Q117-R148 PolarHBondContact O-NH1 3.37Å
118R90.8Very high88.4Confident98 Ų9858.9 Ų58.937%0.3733%0.333SS..EExtended strand (participates in β ladder)trans-118.4109.2165.8-170.3178.8-167.9-168.81.9108.8I120 Q125 V146 R148R118-I120 HydrophobicContact CG-CG1 4.49Å; R118-Q125 HydrophobicContact CG-CG 3.95Å; R118-Q125 VanDerWaalsContact NE-CD 3.31Å; R118-V146 HydrophobicContact CB-CB 4.28Å; R118-V146 VanDerWaalsContact CB-O 3.26Å; R118-V146 WeakPolarHBondContact CB-O 3.33Å; R118-V146 PolarHBondContact N-O 3.18Å; R118-V146 PolarHBondContact O-N 3.03Å; R118-R148 HydrophobicContact CB-CG 4.44Å
119L94.9Very high88.4Confident2 Ų256 Ų561%0.0133%0.334CS..EExtended strand (participates in β ladder)trans-91.2132.9176.7-64.6178.2000110.6V81 V99 V102 K103 I106 L126 L143 H144 L145V81-L119 HydrophobicContact CG1-CD2 4.17Å; V99-L119 HydrophobicContact CG1-CD1 4.28Å; V102-L119 HydrophobicContact CB-CD1 4.34Å; V102-L119 HydrophobicContact CG1-CD1 3.8Å; K103-L119 HydrophobicContact CG-CD1 3.96Å; K103-L119 HydrophobicContact CG-CG 4.49Å; I106-L119 HydrophobicContact CD1-CD1 4.04Å; I106-L119 HydrophobicContact CD1-CD2 3.68Å; I106-L119 HydrophobicContact CD1-CG 4.37Å; L119-L126 HydrophobicContact CB-CB 4.36Å; L119-L126 HydrophobicContact CB-CD1 4.04Å; L119-L126 HydrophobicContact CB-CG 4.36Å; L119-L126 PolarHBondContact O-N 3.39Å; L119-L143 HydrophobicContact CB-CD2 4.43Å; L119-L143 HydrophobicContact CD1-CD2 4.33Å; L119-H144 WeakPolarHBondContact CA-O 3.48Å; L119-L145 HydrophobicContact CD2-CB 4.28Å; L119-L145 HydrophobicContact CD2-CD1 3.97Å
120I95.8Very high88.6Confident40 Ų4055.5 Ų55.521%0.20533%0.329CS..EExtended strand (participates in β ladder)trans-127.7129.9-179.1-56173.8000108.5R118 K124 L143 H144 V146R118-I120 HydrophobicContact CG-CG1 4.49Å; I120-K124 CarbonylContact C-O 3.59Å; I120-K124 WeakPolarHBondContact CA-O 3.39Å; I120-K124 WeakPolarHBondContact CG2-O 3.38Å; I120-L143 CarbonylContact O-C 3.57Å; I120-L143 WeakPolarHBondContact O-CA 3.4Å; I120-H144 HydrophobicContact CB-CB 4.36Å; I120-H144 PolarHBondContact N-O 2.97Å; I120-H144 PolarHBondContact O-N 3.2Å; I120-V146 HydrophobicContact CD1-CG2 3.81Å
121F97Very high88.9Confident42 Ų4253.9 Ų53.918%0.18432%0.323CS..EExtended strand (participates in β ladder)trans-129.6133.1173.5-177.7-115.4000109.5G123 K124 L126 I137 L143F121-G123 PolarHBondContact O-N 3.33Å; F121-G123 VanDerWaalsContact O-N 3.11Å; F121-K124 PolarHBondContact N-O 2.97Å; F121-K124 PolarHBondContact O-N 3.44Å; F121-K124 VanDerWaalsContact O-O 3.14Å; F121-L126 HydrophobicContact CB-CD1 4.28Å; F121-L126 HydrophobicContact CB-CD2 3.89Å; F121-L126 HydrophobicContact CB-CG 4.32Å; F121-I137 HydrophobicContact CB-CD1 4.22Å; F121-I137 HydrophobicContact CB-CG1 4.45Å; F121-I137 HydrophobicContact CD1-CD1 4.05Å; F121-I137 HydrophobicContact CD1-CG1 3.43Å; F121-I137 VanDerWaalsContact CD1-CG1 3.43Å; F121-I137 HydrophobicContact CD2-CG1 4.22Å; F121-I137 HydrophobicContact CE1-CB 4.47Å; F121-I137 HydrophobicContact CE1-CG1 3.55Å; F121-I137 HydrophobicContact CE2-CG1 4.34Å; F121-I137 HydrophobicContact CG-CD1 4.07Å; F121-I137 HydrophobicContact CG-CG1 3.77Å; F121-I137 HydrophobicContact CZ-CG1 4.02Å; F121-L143 HydrophobicContact CB-CG 4.26Å; F121-L143 HydrophobicContact CD2-CD1 3.96Å; F121-L143 HydrophobicContact CD2-CG 4.38Å
122A92.8Very high89.5Confident94 Ų9451 Ų5178%0.77729%0.294SS*.THydrogen-bonded Turntrans4840.2-178.800000114.1K124A122-K124 PolarHBondContact O-N 2.91Å
123G89Confident90Very high77 Ų7752.9 Ų52.979%0.79431%0.309SS*.THydrogen-bonded Turntrans76.6-4.3-178.700000115.5F121F121-G123 PolarHBondContact O-N 3.33Å; F121-G123 VanDerWaalsContact O-N 3.11Å
124K92.5Very high90.6Very high111 Ų11156 Ų5648%0.48333%0.325SS..EExtended strand (participates in β ladder)trans-101.3133.9177.7-167.5178.8176.1-174.50110.7I120 F121 A122 Y135I120-K124 CarbonylContact C-O 3.59Å; I120-K124 WeakPolarHBondContact CA-O 3.39Å; I120-K124 WeakPolarHBondContact CG2-O 3.38Å; F121-K124 PolarHBondContact N-O 2.97Å; F121-K124 PolarHBondContact O-N 3.44Å; F121-K124 VanDerWaalsContact O-O 3.14Å; A122-K124 PolarHBondContact O-N 2.91Å; K124-Y135 HydrophobicContact CD-CE1 4.12Å
125Q91.8Very high91.2Very high73 Ų7356.7 Ų56.734%0.34133%0.325SS..EExtended strand (participates in β ladder)trans-70.6134.3169.7-178-171.2-32.100109.6R118R118-Q125 HydrophobicContact CG-CG 3.95Å; R118-Q125 VanDerWaalsContact NE-CD 3.31Å
126L93.8Very high92.1Very high3 Ų360 Ų602%0.01634%0.343CS..PPolyproline II helixtrans-80.5146.2176-54.5-173.9000111.5V99 L119 F121 Y135 I137 L143V99-L126 HydrophobicContact CB-CB 4.43Å; V99-L126 HydrophobicContact CG1-CB 3.8Å; V99-L126 HydrophobicContact CG2-CB 3.72Å; V99-L126 HydrophobicContact CG2-CD1 4.15Å; L119-L126 HydrophobicContact CB-CB 4.36Å; L119-L126 HydrophobicContact CB-CD1 4.04Å; L119-L126 HydrophobicContact CB-CG 4.36Å; L119-L126 PolarHBondContact O-N 3.39Å; F121-L126 HydrophobicContact CB-CD1 4.28Å; F121-L126 HydrophobicContact CB-CD2 3.89Å; F121-L126 HydrophobicContact CB-CG 4.32Å; L126-Y135 HydrophobicContact CB-CE2 4.29Å; L126-Y135 HydrophobicContact CD2-CD1 3.59Å; L126-Y135 HydrophobicContact CD2-CD2 3.69Å; L126-Y135 HydrophobicContact CD2-CE1 3.74Å; L126-Y135 HydrophobicContact CD2-CE2 3.82Å; L126-Y135 HydrophobicContact CD2-CG 3.57Å; L126-I137 HydrophobicContact CD1-CD1 3.79Å; L126-I137 HydrophobicContact CD2-CD1 4.32Å; L126-L143 HydrophobicContact CD1-CD2 3.59Å; L126-L143 HydrophobicContact CD1-CG 4.24Å
127E88.8Confident92.7Very high96 Ų9658.2 Ų58.245%0.44934%0.335SS..  trans-104.3132.7-179.9-66.3166.1-170.200109.9V99 G129 R130 Y135V99-E127 WeakPolarHBondContact CB-O 2.83Å; V99-E127 WeakPolarHBondContact CG2-O 3.25Å; E127-G129 VanDerWaalsContact C-N 3.33Å; E127-G129 PolarHBondContact O-N 3.23Å; E127-R130 HydrophobicContact CB-CG 4.46Å; E127-R130 PolarHBondContact O-N 3.1Å; E127-R130 VanDerWaalsContact O-N 3.14Å; E127-R130 IonicContact OE2-CZ 2.85Å; E127-R130 IonicContact OE2-NE 3.1Å; E127-R130 PolarHBondContact OE2-NE 2.89Å; E127-R130 IonicContact OE2-NH2 2.7Å; E127-Y135 WeakPolarHBondContact CB-OH 3.45Å; E127-Y135 WeakPolarHBondContact CG-OH 3.45Å; E127-Y135 PolarHBondContact N-OH 3.09Å
128D85.8Confident92.9Very high67 Ų6763.9 Ų63.936%0.35836%0.361SS..THydrogen-bonded Turntrans-56-40.1-167.9-69.1-0.3000114.1V99 E100 K103 R130V99-D128 PolarHBondContact N-O 3.43Å; E100-D128 HydrophobicContact CB-CB 4.28Å; E100-D128 PolarHBondContact N-O 3.19Å; E100-D128 VanDerWaalsContact N-O 3.12Å; K103-D128 WeakPolarHBondContact CE-OD1 3.47Å; K103-D128 IonicContact NZ-OD1 2.6Å; K103-D128 PolarHBondContact NZ-OD1 2.74Å; K103-D128 IonicContact NZ-OD2 2.81Å; K103-D128 PolarHBondContact NZ-OD2 3.09Å; D128-R130 VanDerWaalsContact C-N 3.35Å; D128-R130 PolarHBondContact O-N 2.88Å
129G85.5Confident93Very high71 Ų7165.4 Ų65.473%0.73237%0.37SS*.THydrogen-bonded Turntrans-82.21.7-177.600000116.4E127E127-G129 VanDerWaalsContact C-N 3.33Å; E127-G129 PolarHBondContact O-N 3.23Å
130R91.7Very high92.9Very high112 Ų11271.1 Ų71.142%0.42340%0.397SS..SBendtrans-100.5153.2177.6-71.9-159.7-166.5-123-2.6111.4T98 V99 E127 D128 D134 Y135T98-R130 CarbonylContact C-O 3.45Å; T98-R130 VanDerWaalsContact CA-O 3.32Å; T98-R130 WeakPolarHBondContact CA-O 3.43Å; V99-R130 WeakPolarHBondContact CG2-O 3.32Å; V99-R130 PolarHBondContact N-O 3.32Å; E127-R130 HydrophobicContact CB-CG 4.46Å; E127-R130 PolarHBondContact O-N 3.1Å; E127-R130 VanDerWaalsContact O-N 3.14Å; E127-R130 IonicContact OE2-CZ 2.85Å; E127-R130 IonicContact OE2-NE 3.1Å; E127-R130 PolarHBondContact OE2-NE 2.89Å; E127-R130 IonicContact OE2-NH2 2.7Å; D128-R130 VanDerWaalsContact C-N 3.35Å; D128-R130 PolarHBondContact O-N 2.88Å; R130-D134 HydrophobicContact CB-CB 4.22Å; R130-Y135 HydrophobicContact CB-CD2 4.29Å; R130-Y135 HydrophobicContact CB-CE2 3.54Å; R130-Y135 HydrophobicContact CG-CE2 4.32Å
131T95.6Very high92.9Very high29 Ų2970.2 Ų70.218%0.17839%0.394CS..BIsolated β-bridgetrans-85.3167.5179.8670000112.7S96 D97 S133 D134 Y135S96-T131 WeakPolarHBondContact O-CG2 3.38Å; D97-T131 CarbonylContact O-C 3.58Å; D97-T131 WeakPolarHBondContact O-CA 3.19Å; T131-S133 VanDerWaalsContact C-N 3.28Å; T131-S133 PolarHBondContact O-N 3.36Å; T131-S133 PolarHBondContact OG1-N 2.84Å; T131-S133 PolarHBondContact OG1-OG 3.35Å; T131-D134 PolarHBondContact N-OD2 2.77Å; T131-D134 WeakPolarHBondContact O-CB 3.42Å; T131-D134 PolarHBondContact O-N 2.72Å; T131-D134 VanDerWaalsContact OG1-CG 3.22Å; T131-D134 PolarHBondContact OG1-N 2.93Å; T131-D134 VanDerWaalsContact OG1-N 3.13Å; T131-D134 PolarHBondContact OG1-OD2 3.39Å; T131-Y135 WeakPolarHBondContact O-CD2 3.26Å
132L95.5Very high92.9Very high0 Ų071 Ų710%040%0.402CS..THydrogen-bonded Turntrans-60.5-38.3169.8-68.8-175.4000112.2M77 I79 V93 D97 V102 Y135 N136 I137M77-L132 HydrophobicContact CE-CD1 4.37Å; I79-L132 HydrophobicContact CD1-CD1 4.25Å; V93-L132 HydrophobicContact CB-CD1 3.61Å; V93-L132 HydrophobicContact CG1-CD1 4.14Å; V93-L132 HydrophobicContact CG2-CD1 3.47Å; V93-L132 VanDerWaalsContact CG2-CD1 3.47Å; D97-L132 HydrophobicContact CB-CD1 4.29Å; D97-L132 HydrophobicContact CB-CG 4.45Å; D97-L132 PolarHBondContact O-N 2.91Å; V102-L132 HydrophobicContact CG2-CD1 4.09Å; V102-L132 HydrophobicContact CG2-CD2 3.99Å; V102-L132 HydrophobicContact CG2-CG 4.13Å; L132-Y135 PolarHBondContact O-N 2.86Å; L132-N136 PolarHBondContact O-N 3.13Å; L132-I137 HydrophobicContact CB-CB 4.25Å; L132-I137 HydrophobicContact CD2-CB 4.23Å; L132-I137 HydrophobicContact CD2-CD1 3.59Å; L132-I137 HydrophobicContact CD2-CG2 4.14Å; L132-I137 WeakPolarHBondContact O-CB 3.39Å; L132-I137 PolarHBondContact O-N 3.07Å
133S94.3Very high93.1Very high65 Ų6566.5 Ų66.546%0.45537%0.365SS..G310 helixtrans-64.8-35.4176.860.50000113.1P95 T131 Y135 N136P95-S133 WeakPolarHBondContact O-CB 3.5Å; P95-S133 PolarHBondContact O-N 3.21Å; P95-S133 PolarHBondContact O-OG 3.01Å; T131-S133 VanDerWaalsContact C-N 3.28Å; T131-S133 PolarHBondContact O-N 3.36Å; T131-S133 PolarHBondContact OG1-N 2.84Å; T131-S133 PolarHBondContact OG1-OG 3.35Å; S133-Y135 PolarHBondContact O-N 3.39Å; S133-N136 PolarHBondContact O-N 3.08Å
134D95Very high93.5Very high96 Ų9667.3 Ų67.351%0.51335%0.348SS..G310 helixtrans-59.6-30.3176-71.2-27.3000112.8R130 T131R130-D134 HydrophobicContact CB-CB 4.22Å; T131-D134 PolarHBondContact N-OD2 2.77Å; T131-D134 WeakPolarHBondContact O-CB 3.42Å; T131-D134 PolarHBondContact O-N 2.72Å; T131-D134 VanDerWaalsContact OG1-CG 3.22Å; T131-D134 PolarHBondContact OG1-N 2.93Å; T131-D134 VanDerWaalsContact OG1-N 3.13Å; T131-D134 PolarHBondContact OG1-OD2 3.39Å
135Y95.5Very high93.6Very high29 Ų2962.1 Ų62.111%0.11433%0.326CS..G310 helixtrans-95.74.2176.5-70.9-76.1000113.5V99 K124 L126 E127 R130 T131 L132 S133 I137V99-Y135 HydrophobicContact CG2-CD2 4.48Å; V99-Y135 HydrophobicContact CG2-CE2 4.16Å; K124-Y135 HydrophobicContact CD-CE1 4.12Å; L126-Y135 HydrophobicContact CB-CE2 4.29Å; L126-Y135 HydrophobicContact CD2-CD1 3.59Å; L126-Y135 HydrophobicContact CD2-CD2 3.69Å; L126-Y135 HydrophobicContact CD2-CE1 3.74Å; L126-Y135 HydrophobicContact CD2-CE2 3.82Å; L126-Y135 HydrophobicContact CD2-CG 3.57Å; E127-Y135 WeakPolarHBondContact CB-OH 3.45Å; E127-Y135 WeakPolarHBondContact CG-OH 3.45Å; E127-Y135 PolarHBondContact N-OH 3.09Å; R130-Y135 HydrophobicContact CB-CD2 4.29Å; R130-Y135 HydrophobicContact CB-CE2 3.54Å; R130-Y135 HydrophobicContact CG-CE2 4.32Å; T131-Y135 WeakPolarHBondContact O-CD2 3.26Å; L132-Y135 PolarHBondContact O-N 2.86Å; S133-Y135 PolarHBondContact O-N 3.39Å; Y135-I137 PolarHBondContact O-N 3.09Å
136N95.4Very high93.6Very high113 Ų11360.4 Ų60.460%0.60432%0.32SS*.THydrogen-bonded Turntrans52.136.8-174.1-160.523.2000112.3L132 S133 Q138L132-N136 PolarHBondContact O-N 3.13Å; S133-N136 PolarHBondContact O-N 3.08Å; N136-Q138 PolarHBondContact O-N 3.32Å; N136-Q138 PolarHBondContact OD1-NE2 2.95Å
137I95Very high93.2Very high5 Ų564.2 Ų64.23%0.02634%0.34CS..  trans-74.3118.6173.5-67.4166.1000106.7M77 I79 F121 L126 L132 Y135 L143M77-I137 HydrophobicContact CE-CG2 4.37Å; M77-I137 WeakPolarHBondContact CE-O 3.35Å; I79-I137 HydrophobicContact CG2-CG2 3.99Å; F121-I137 HydrophobicContact CB-CD1 4.22Å; F121-I137 HydrophobicContact CB-CG1 4.45Å; F121-I137 HydrophobicContact CD1-CD1 4.05Å; F121-I137 HydrophobicContact CD1-CG1 3.43Å; F121-I137 VanDerWaalsContact CD1-CG1 3.43Å; F121-I137 HydrophobicContact CD2-CG1 4.22Å; F121-I137 HydrophobicContact CE1-CB 4.47Å; F121-I137 HydrophobicContact CE1-CG1 3.55Å; F121-I137 HydrophobicContact CE2-CG1 4.34Å; F121-I137 HydrophobicContact CG-CD1 4.07Å; F121-I137 HydrophobicContact CG-CG1 3.77Å; F121-I137 HydrophobicContact CZ-CG1 4.02Å; L126-I137 HydrophobicContact CD1-CD1 3.79Å; L126-I137 HydrophobicContact CD2-CD1 4.32Å; L132-I137 HydrophobicContact CB-CB 4.25Å; L132-I137 HydrophobicContact CD2-CB 4.23Å; L132-I137 HydrophobicContact CD2-CD1 3.59Å; L132-I137 HydrophobicContact CD2-CG2 4.14Å; L132-I137 WeakPolarHBondContact O-CB 3.39Å; L132-I137 PolarHBondContact O-N 3.07Å; Y135-I137 PolarHBondContact O-N 3.09Å; I137-L143 HydrophobicContact CD1-CD1 4.22Å; I137-L143 HydrophobicContact CD1-CD2 4.41Å; I137-L143 HydrophobicContact CG2-CD1 3.98Å
138Q93.4Very high92.6Very high119 Ų11963.6 Ų63.656%0.55633%0.334SS*.  trans-105.5171.3-178.5-58.8-153.8-1000111.8N136 E140 S141N136-Q138 PolarHBondContact O-N 3.32Å; N136-Q138 PolarHBondContact OD1-NE2 2.95Å; Q138-E140 PolarHBondContact O-N 3.19Å; Q138-S141 PolarHBondContact N-OG 3.23Å; Q138-S141 WeakPolarHBondContact O-CB 3.2Å; Q138-S141 PolarHBondContact O-N 3.31Å; Q138-S141 PolarHBondContact O-OG 2.96Å
139K93.1Very high91.3Very high129 Ų12968.3 Ų68.356%0.56136%0.358SS*.THydrogen-bonded Turntrans-50138.6172.2-177.3174176.1178.80110.6M77 S141M77-K139 HydrophobicContact CG-CB 4.01Å; K139-S141 PolarHBondContact O-N 3.32Å
140E93.6Very high89.8Confident123 Ų12375.6 Ų75.658%0.57536%0.364SS*.THydrogen-bonded Turntrans65.910.1-177.1-66.1165.9-161.800115.4Q78 F80 Q138Q78-E140 PolarHBondContact O-N 3.07Å; F80-E140 HydrophobicContact CE2-CB 3.92Å; F80-E140 HydrophobicContact CE2-CG 3.94Å; Q138-E140 PolarHBondContact O-N 3.19Å
141S96.6Very high88.2Confident20 Ų2072.1 Ų72.114%0.1436%0.362CS..  trans-60.6145171.1-67.90000111.9F80 Q138 K139F80-S141 PolarHBondContact N-O 2.97Å; Q138-S141 PolarHBondContact N-OG 3.23Å; Q138-S141 WeakPolarHBondContact O-CB 3.2Å; Q138-S141 PolarHBondContact O-N 3.31Å; Q138-S141 PolarHBondContact O-OG 2.96Å; K139-S141 PolarHBondContact O-N 3.32Å
142T96.8Very high86.7Confident58 Ų5870.8 Ų70.836%0.35636%0.355SS..EExtended strand (participates in β ladder)trans-107.3114.5175.7-57.40000111.1F80 K82F80-T142 CarbonylContact O-C 3.52Å; F80-T142 VanDerWaalsContact O-CA 3.3Å; F80-T142 WeakPolarHBondContact O-CA 3.21Å; K82-T142 HydrophobicContact CB-CG2 4.21Å; K82-T142 HydrophobicContact CD-CG2 4.21Å; K82-T142 HydrophobicContact CG-CG2 4.31Å
143L97.3Very high86.1Confident0 Ų072.1 Ų72.10%036%0.361CS..EExtended strand (participates in β ladder)trans-90.2151.8167.9-77.364.8000109.3I79 F80 V81 K82 L119 I120 F121 L126 I137I79-L143 HydrophobicContact CD1-CD1 4.21Å; I79-L143 HydrophobicContact CD1-CD2 4.29Å; F80-L143 PolarHBondContact O-N 3.43Å; V81-L143 CarbonylContact C-O 3.5Å; V81-L143 WeakPolarHBondContact CA-O 3.41Å; V81-L143 HydrophobicContact CG2-CB 4.37Å; K82-L143 PolarHBondContact N-O 3.29Å; L119-L143 HydrophobicContact CB-CD2 4.43Å; L119-L143 HydrophobicContact CD1-CD2 4.33Å; I120-L143 CarbonylContact O-C 3.57Å; I120-L143 WeakPolarHBondContact O-CA 3.4Å; F121-L143 HydrophobicContact CB-CG 4.26Å; F121-L143 HydrophobicContact CD2-CD1 3.96Å; F121-L143 HydrophobicContact CD2-CG 4.38Å; L126-L143 HydrophobicContact CD1-CD2 3.59Å; L126-L143 HydrophobicContact CD1-CG 4.24Å; I137-L143 HydrophobicContact CD1-CD1 4.22Å; I137-L143 HydrophobicContact CD1-CD2 4.41Å; I137-L143 HydrophobicContact CG2-CD1 3.98Å
144H97.2Very high85.7Confident94 Ų9472 Ų7244%0.43535%0.353SS..EExtended strand (participates in β ladder)trans-106128.4171.8-67.172.8000109.7K82 L119 I120K82-H144 CarbonylContact O-C 3.56Å; K82-H144 WeakPolarHBondContact O-CA 3.46Å; L119-H144 WeakPolarHBondContact CA-O 3.48Å; I120-H144 HydrophobicContact CB-CB 4.36Å; I120-H144 PolarHBondContact N-O 2.97Å; I120-H144 PolarHBondContact O-N 3.2Å
145L94.8Very high85.5Confident3 Ų367.5 Ų67.52%0.01633%0.329CS..EExtended strand (participates in β ladder)trans-96.4117173.3175.863.5000109.8V81 K82 T83 I106 I112 Q117 L119 L147V81-L145 HydrophobicContact CG1-CB 3.54Å; V81-L145 HydrophobicContact CG1-CD2 4.47Å; K82-L145 PolarHBondContact O-N 3.43Å; T83-L145 HydrophobicContact CG2-CD2 4.44Å; I106-L145 HydrophobicContact CG2-CD2 4.11Å; I112-L145 HydrophobicContact CD1-CD2 4.04Å; Q117-L145 HydrophobicContact CB-CD1 3.74Å; Q117-L145 HydrophobicContact CG-CD1 3.91Å; L119-L145 HydrophobicContact CD2-CB 4.28Å; L119-L145 HydrophobicContact CD2-CD1 3.97Å; L145-L147 HydrophobicContact CD1-CD2 4.23Å; L145-L147 HydrophobicContact CD2-CD2 4.12Å; L145-L147 HydrophobicContact CG-CD2 4.06Å
146V90.8Very high85.2Confident37 Ų3768.5 Ų68.522%0.22433%0.334CS..EExtended strand (participates in β ladder)trans-109.8124.3170.9177.50000108.2L84 R118 I120L84-V146 HydrophobicContact CD1-CG1 4.17Å; L84-V146 HydrophobicContact CD1-CG2 4.4Å; L84-V146 HydrophobicContact CD2-CG2 4.24Å; L84-V146 HydrophobicContact CG-CG2 4.36Å; R118-V146 HydrophobicContact CB-CB 4.28Å; R118-V146 VanDerWaalsContact CB-O 3.26Å; R118-V146 WeakPolarHBondContact CB-O 3.33Å; R118-V146 PolarHBondContact N-O 3.18Å; R118-V146 PolarHBondContact O-N 3.03Å; I120-V146 HydrophobicContact CD1-CG2 3.81Å
147L85.6Confident85Confident82 Ų8263.1 Ų63.143%0.42931%0.306SS..EExtended strand (participates in β ladder)trans-81.5128177.8-58-178.1000110.2I112 Q116 L145I112-L147 HydrophobicContact CD1-CD2 4.05Å; I112-L147 HydrophobicContact CG2-CD2 3.61Å; Q116-L147 CarbonylContact O-C 3.49Å; Q116-L147 WeakPolarHBondContact O-CA 3.45Å; L145-L147 HydrophobicContact CD1-CD2 4.23Å; L145-L147 HydrophobicContact CD2-CD2 4.12Å; L145-L147 HydrophobicContact CG-CD2 4.06Å
148R75.9Confident84.6Confident84 Ų8467.2 Ų67.232%0.31732%0.323SS..  trans-82.6123.8168.4-64.1-170.6-178.397.6-0.6108.4Q116 Q117 R118 R150Q116-R148 PolarHBondContact O-N 3.2Å; Q117-R148 PolarHBondContact O-NH1 3.37Å; R118-R148 HydrophobicContact CB-CG 4.44Å; R148-R150 VanDerWaalsContact C-N 3.33Å; R148-R150 PolarHBondContact O-N 2.9Å
149L58.7Low84.1Confident165 Ų16562.9 Ų62.986%0.86431%0.305SS*.THydrogen-bonded Turntrans-74.1-12.5-172.6-73.2169.8000115.2
150R54.5Low83.3Confident225 Ų22561.5 Ų61.585%0.84930%0.303SS*.THydrogen-bonded Turntrans-15541.3-173.1-66.6-167.9-176.7169.81115.4R148R148-R150 VanDerWaalsContact C-N 3.33Å; R148-R150 PolarHBondContact O-N 2.9Å
151G57Low82.4Confident38 Ų3861.7 Ų61.739%0.39231%0.312SS..  trans-87.2-36.2-17300000115.8
152G65.4Low81.4Confident2 Ų263.3 Ų63.32%0.02133%0.333CS..SBendtrans-73.2154.8-161.100000116D115 Q154D115-G152 WeakPolarHBondContact OD2-CA 3.29Å; G152-Q154 PolarHBondContact O-N 3.1Å
153M82.2Confident80.8Confident27 Ų2765.6 Ų65.613%0.13334%0.338CS..EExtended strand (participates in β ladder)trans-66.7106.9170.4169.3172.3155.400107.4I155 V169 P171 L222 I227 K229M153-I155 HydrophobicContact CE-CG2 3.87Å; M153-V169 WeakPolarHBondContact CB-O 3.36Å; M153-V169 HydrophobicContact CE-CG2 4.2Å; M153-V169 HydrophobicContact CG-CG2 4.08Å; M153-V169 VanDerWaalsContact O-CG2 3.27Å; M153-V169 WeakPolarHBondContact O-CG2 3.25Å; M153-V169 PolarHBondContact O-N 3.09Å; M153-V169 VanDerWaalsContact O-O 3.05Å; M153-P171 HydrophobicContact SD-CG 3.94Å; M153-L222 HydrophobicContact CE-CD1 4.18Å; M153-I227 HydrophobicContact CE-CG2 4.08Å; M153-I227 WeakPolarHBondContact CE-O 3.5Å; M153-K229 HydrophobicContact CG-CB 4.2Å
154Q85.3Confident80.3Confident64 Ų6468.7 Ų68.730%0.29936%0.357SS..EExtended strand (participates in β ladder)trans-89.9136.8174.5-75.8179.54.200109.7G152 T166 L167 E168 E230G152-Q154 PolarHBondContact O-N 3.1Å; Q154-T166 HydrophobicContact CB-CG2 4.34Å; Q154-T166 HydrophobicContact CG-CG2 4.32Å; Q154-L167 CarbonylContact C-O 3.44Å; Q154-L167 VanDerWaalsContact CA-O 3.25Å; Q154-L167 WeakPolarHBondContact CA-O 3.21Å; Q154-E168 HydrophobicContact CG-CG 3.69Å; Q154-E168 PolarHBondContact NE2-OE1 3.32Å; Q154-E230 WeakPolarHBondContact O-CA 3.28Å; Q154-E230 PolarHBondContact O-N 3.2Å
155I90.6Very high79.7Confident0 Ų064.6 Ų64.60%034%0.338CS..EExtended strand (participates in β ladder)trans-123.3156.8168.663.3170.8000109.1M153 L167 V169 V178 L222 I227 S231 L233M153-I155 HydrophobicContact CE-CG2 3.87Å; I155-L167 HydrophobicContact CG1-CB 3.97Å; I155-L167 PolarHBondContact N-O 3.25Å; I155-L167 PolarHBondContact O-N 2.94Å; I155-V169 HydrophobicContact CB-CG2 4.3Å; I155-V169 HydrophobicContact CD1-CB 4.47Å; I155-V169 HydrophobicContact CD1-CG1 3.81Å; I155-V169 HydrophobicContact CD1-CG2 3.91Å; I155-V169 HydrophobicContact CG1-CG1 3.96Å; I155-V169 HydrophobicContact CG1-CG2 3.75Å; I155-V169 HydrophobicContact CG2-CG2 3.73Å; I155-V178 HydrophobicContact CD1-CG1 4.24Å; I155-L222 HydrophobicContact CD1-CD1 4.22Å; I155-L222 HydrophobicContact CD1-CD2 4.37Å; I155-I227 HydrophobicContact CG2-CG2 3.91Å; I155-S231 WeakPolarHBondContact CA-O 3.22Å; I155-L233 HydrophobicContact CB-CD1 4.18Å; I155-L233 HydrophobicContact CD1-CD1 3.82Å; I155-L233 HydrophobicContact CD1-CD2 4.38Å; I155-L233 HydrophobicContact CG1-CD1 4.46Å
156F90.5Very high79.4Confident51 Ų5167 Ų6722%0.22435%0.353CS..EExtended strand (participates in β ladder)trans-110.3136.2178.7-56.3-71.7000110.1T164 I165 T166 E230 S231 T232 L233F156-T164 HydrophobicContact CB-CG2 4.06Å; F156-T164 HydrophobicContact CD1-CG2 4.17Å; F156-T164 HydrophobicContact CG-CG2 4.45Å; F156-I165 CarbonylContact C-O 3.59Å; F156-I165 WeakPolarHBondContact CA-O 3.43Å; F156-T166 HydrophobicContact CD1-CG2 4.13Å; F156-T166 HydrophobicContact CE1-CG2 3.84Å; F156-E230 HydrophobicContact CE2-CB 3.89Å; F156-E230 HydrophobicContact CE2-CG 4.14Å; F156-S231 PolarHBondContact N-O 2.99Å; F156-T232 HydrophobicContact CB-CG2 4.35Å; F156-T232 CarbonylContact O-C 3.58Å; F156-T232 VanDerWaalsContact O-CA 3.27Å; F156-T232 WeakPolarHBondContact O-CA 3.28Å; F156-L233 PolarHBondContact O-N 3.2Å
157V91.2Very high79.2Confident0 Ų065.3 Ų65.30%034%0.343CS..EExtended strand (participates in β ladder)trans-115.7115173.6-177.70000108.1I165 L167 I182 L195 L233 L235V157-I165 HydrophobicContact CB-CB 4.28Å; V157-I165 HydrophobicContact CB-CD1 4.49Å; V157-I165 HydrophobicContact CG1-CD1 4.45Å; V157-I165 PolarHBondContact N-O 3.08Å; V157-I165 PolarHBondContact O-N 3.05Å; V157-L167 HydrophobicContact CG2-CD1 3.58Å; V157-L167 HydrophobicContact CG2-CG 4.22Å; V157-I182 HydrophobicContact CG1-CD1 4.15Å; V157-I182 HydrophobicContact CG2-CD1 4.15Å; V157-L195 HydrophobicContact CG1-CD2 4.03Å; V157-L233 WeakPolarHBondContact CA-O 3.42Å; V157-L233 HydrophobicContact CG2-CB 4.38Å; V157-L235 HydrophobicContact CG1-CB 3.57Å; V157-L235 HydrophobicContact CG1-CD2 4.49Å
158K86.6Confident79.2Confident91 Ų9164.2 Ų64.240%0.39634%0.335SS..EExtended strand (participates in β ladder)trans-98.7130177.6-78.5-169.7175.3-174.90111.4K163 T164 T232 L233 H234 L235K158-K163 WeakPolarHBondContact CA-O 3.39Å; K158-T164 VanDerWaalsContact CE-OG1 3.29Å; K158-T164 WeakPolarHBondContact CE-OG1 3.12Å; K158-T164 HydrophobicContact CG-CG2 4.1Å; K158-T232 HydrophobicContact CB-CG2 4.33Å; K158-T232 HydrophobicContact CD-CG2 4.02Å; K158-T232 HydrophobicContact CG-CG2 3.93Å; K158-L233 PolarHBondContact N-O 3.28Å; K158-H234 CarbonylContact O-C 3.6Å; K158-H234 WeakPolarHBondContact O-CA 3.44Å; K158-L235 PolarHBondContact O-N 2.93Å
159T82.8Confident79.7Confident28 Ų2860.3 Ų60.317%0.17232%0.321CS..EExtended strand (participates in β ladder)trans-83.9162.5171.967.90000110.8T161 G162 K163 I165 L235T159-T161 PolarHBondContact O-N 3.28Å; T159-T161 PolarHBondContact OG1-N 3.31Å; T159-T161 PolarHBondContact OG1-OG1 3.13Å; T159-G162 PolarHBondContact O-N 3.45Å; T159-G162 PolarHBondContact OG1-N 2.92Å; T159-K163 HydrophobicContact CG2-CB 4.25Å; T159-K163 PolarHBondContact N-O 2.91Å; T159-K163 WeakPolarHBondContact OG1-CB 3.32Å; T159-K163 PolarHBondContact OG1-N 3.49Å; T159-K163 VanDerWaalsContact OG1-N 3.11Å; T159-K163 PolarHBondContact OG1-O 3.05Å; T159-I165 HydrophobicContact CG2-CD1 4.23Å; T159-L235 HydrophobicContact CG2-CD2 4.38Å
160L75.7Confident81Confident100 Ų10055 Ų5552%0.52429%0.291SS..THydrogen-bonded Turntrans-60.7-23.9170.1-72.9171000113.2G162 I210 V236L160-G162 PolarHBondContact O-N 2.86Å; L160-I210 HydrophobicContact CD2-CD1 3.24Å; L160-I210 HydrophobicContact CG-CD1 4.41Å; L160-V236 HydrophobicContact CD1-CG1 4.34Å; L160-V236 HydrophobicContact CD1-CG2 4.45Å
161T74.6Confident82.5Confident126 Ų12647.5 Ų47.577%0.77327%0.272SS*.THydrogen-bonded Turntrans-77-5.5175.560.80000113.2T159T159-T161 PolarHBondContact O-N 3.28Å; T159-T161 PolarHBondContact OG1-N 3.31Å; T159-T161 PolarHBondContact OG1-OG1 3.13Å
162G75.8Confident83.9Confident55 Ų5549.1 Ų49.157%0.56728%0.277SS*.SBendtrans89.7-4.4-17900000114.6T159 L160T159-G162 PolarHBondContact O-N 3.45Å; T159-G162 PolarHBondContact OG1-N 2.92Å; L160-G162 PolarHBondContact O-N 2.86Å
163K84.6Confident85Confident105 Ų10549.8 Ų49.846%0.45728%0.28SS..  trans-64135.9174.3-172.5176.9177.1-175.80109.5K158 T159 E186K158-K163 WeakPolarHBondContact CA-O 3.39Å; T159-K163 HydrophobicContact CG2-CB 4.25Å; T159-K163 PolarHBondContact N-O 2.91Å; T159-K163 WeakPolarHBondContact OG1-CB 3.32Å; T159-K163 PolarHBondContact OG1-N 3.49Å; T159-K163 VanDerWaalsContact OG1-N 3.11Å; T159-K163 PolarHBondContact OG1-O 3.05Å; K163-E186 VanDerWaalsContact CE-OE1 3.3Å; K163-E186 WeakPolarHBondContact CE-OE1 3.38Å; K163-E186 WeakPolarHBondContact CE-OE2 3.3Å; K163-E186 IonicContact NZ-OE1 2.69Å; K163-E186 PolarHBondContact NZ-OE1 3.15Å; K163-E186 IonicContact NZ-OE2 3.15Å; K163-E186 PolarHBondContact NZ-OE2 3.49Å
164T86Confident85.6Confident66 Ų6650 Ų5041%0.40528%0.284SS..EExtended strand (participates in β ladder)trans-113.3119.9176.6-54.70000109.2F156 K158F156-T164 HydrophobicContact CB-CG2 4.06Å; F156-T164 HydrophobicContact CD1-CG2 4.17Å; F156-T164 HydrophobicContact CG-CG2 4.45Å; K158-T164 VanDerWaalsContact CE-OG1 3.29Å; K158-T164 WeakPolarHBondContact CE-OG1 3.12Å; K158-T164 HydrophobicContact CG-CG2 4.1Å
165I85.4Confident86.1Confident7 Ų747 Ų474%0.03627%0.269CS..EExtended strand (participates in β ladder)trans-101.1130.4177.3-54.1150.4000107.1F156 V157 T159 L167 K185 E186F156-I165 CarbonylContact C-O 3.59Å; F156-I165 WeakPolarHBondContact CA-O 3.43Å; V157-I165 HydrophobicContact CB-CB 4.28Å; V157-I165 HydrophobicContact CB-CD1 4.49Å; V157-I165 HydrophobicContact CG1-CD1 4.45Å; V157-I165 PolarHBondContact N-O 3.08Å; V157-I165 PolarHBondContact O-N 3.05Å; T159-I165 HydrophobicContact CG2-CD1 4.23Å; I165-L167 HydrophobicContact CG2-CD2 3.98Å; I165-L167 HydrophobicContact CG2-CG 4.38Å; I165-K185 HydrophobicContact CG2-CD 4.16Å; I165-E186 HydrophobicContact CD1-CG 3.63Å; I165-E186 HydrophobicContact CG1-CG 4Å
166T88.3Confident86.2Confident54 Ų5449.9 Ų49.933%0.33129%0.285SS..EExtended strand (participates in β ladder)trans-98.3126174.7-53.50000108.7Q154 F156 K185Q154-T166 HydrophobicContact CB-CG2 4.34Å; Q154-T166 HydrophobicContact CG-CG2 4.32Å; F156-T166 HydrophobicContact CD1-CG2 4.13Å; F156-T166 HydrophobicContact CE1-CG2 3.84Å; T166-K185 PolarHBondContact O-NZ 3.19Å
167L87.3Confident86.2Confident2 Ų250.8 Ų50.81%0.0129%0.292CS..EExtended strand (participates in β ladder)trans-116.3141.6177.6-60.8177.9000110.1Q154 I155 V157 I165 V169 V178 K181 I182 K185Q154-L167 CarbonylContact C-O 3.44Å; Q154-L167 VanDerWaalsContact CA-O 3.25Å; Q154-L167 WeakPolarHBondContact CA-O 3.21Å; I155-L167 HydrophobicContact CG1-CB 3.97Å; I155-L167 PolarHBondContact N-O 3.25Å; I155-L167 PolarHBondContact O-N 2.94Å; V157-L167 HydrophobicContact CG2-CD1 3.58Å; V157-L167 HydrophobicContact CG2-CG 4.22Å; I165-L167 HydrophobicContact CG2-CD2 3.98Å; I165-L167 HydrophobicContact CG2-CG 4.38Å; L167-V169 HydrophobicContact CB-CG1 4.1Å; L167-V178 HydrophobicContact CD1-CG1 3.9Å; L167-K181 HydrophobicContact CD2-CB 4.23Å; L167-I182 HydrophobicContact CD1-CD1 4.19Å; L167-I182 HydrophobicContact CD1-CG1 3.63Å; L167-I182 HydrophobicContact CD2-CG1 4.47Å; L167-K185 HydrophobicContact CD2-CD 3.97Å
168E84.7Confident86.3Confident59 Ų5950.8 Ų50.828%0.27629%0.292SS..EExtended strand (participates in β ladder)trans-97.2126.5166-73.4-170.917200109.1Q116 Q154 K181Q116-E168 PolarHBondContact NE2-OE2 2.91Å; Q154-E168 HydrophobicContact CG-CG 3.69Å; Q154-E168 PolarHBondContact NE2-OE1 3.32Å; E168-K181 WeakPolarHBondContact O-CD 3.42Å; E168-K181 PolarHBondContact O-NZ 2.94Å
169V87.3Confident86.7Confident1 Ų146.8 Ų46.81%0.00627%0.274CS..EExtended strand (participates in β ladder)trans-142.1160.2-169.7-63.50000110.6M153 I155 L167 D173 V178 K181 L222M153-V169 WeakPolarHBondContact CB-O 3.36Å; M153-V169 HydrophobicContact CE-CG2 4.2Å; M153-V169 HydrophobicContact CG-CG2 4.08Å; M153-V169 VanDerWaalsContact O-CG2 3.27Å; M153-V169 WeakPolarHBondContact O-CG2 3.25Å; M153-V169 PolarHBondContact O-N 3.09Å; M153-V169 VanDerWaalsContact O-O 3.05Å; I155-V169 HydrophobicContact CB-CG2 4.3Å; I155-V169 HydrophobicContact CD1-CB 4.47Å; I155-V169 HydrophobicContact CD1-CG1 3.81Å; I155-V169 HydrophobicContact CD1-CG2 3.91Å; I155-V169 HydrophobicContact CG1-CG1 3.96Å; I155-V169 HydrophobicContact CG1-CG2 3.75Å; I155-V169 HydrophobicContact CG2-CG2 3.73Å; L167-V169 HydrophobicContact CB-CG1 4.1Å; V169-D173 VanDerWaalsContact CA-OD2 3.31Å; V169-D173 WeakPolarHBondContact CA-OD2 3.4Å; V169-V178 HydrophobicContact CG1-CG2 4.3Å; V169-K181 HydrophobicContact CG1-CD 4.24Å; V169-L222 HydrophobicContact CB-CD1 3.58Å; V169-L222 HydrophobicContact CG1-CD1 4.14Å; V169-L222 HydrophobicContact CG2-CD1 3.39Å
170E84.5Confident87.1Confident54 Ų5448.3 Ų48.325%0.25228%0.284SS..  trans-106.2151.7168.9-64.8-172.2173.400110.5P114 S172 D173P114-E170 WeakPolarHBondContact CD-OE1 3.44Å; E170-S172 PolarHBondContact O-N 3.39Å; E170-S172 VanDerWaalsContact O-N 3.09Å; E170-D173 PolarHBondContact N-OD2 2.84Å; E170-D173 VanDerWaalsContact O-CB 3.31Å; E170-D173 WeakPolarHBondContact O-CB 3.26Å; E170-D173 PolarHBondContact O-N 2.75Å
171P86.6Confident87.7Confident67 Ų6746 Ų4644%0.43527%0.27SS..THydrogen-bonded Turntrans-56.9-26.1176.6-24.333.3000114M153 S223M153-P171 HydrophobicContact SD-CG 3.94Å; P171-S223 VanDerWaalsContact O-CB 3.3Å; P171-S223 WeakPolarHBondContact O-CB 3.36Å; P171-S223 PolarHBondContact O-N 3.32Å; P171-S223 PolarHBondContact O-OG 3.47Å
172S86.7Confident88.5Confident72 Ų7240 Ų4050%0.50323%0.233SC..THydrogen-bonded Turntrans-80.3-12.9176.145.60000113.8E170 T174 T221E170-S172 PolarHBondContact O-N 3.39Å; E170-S172 VanDerWaalsContact O-N 3.09Å; S172-T174 PolarHBondContact O-N 3.25Å; S172-T221 WeakPolarHBondContact O-CG2 3.48Å
173D89.1Confident89.2Confident16 Ų1639.9 Ų39.99%0.08622%0.217CC..  trans-59.7129.8179.2-88.1-33.3000110V169 E170 N177 V178 K181 T221 L222V169-D173 VanDerWaalsContact CA-OD2 3.31Å; V169-D173 WeakPolarHBondContact CA-OD2 3.4Å; E170-D173 PolarHBondContact N-OD2 2.84Å; E170-D173 VanDerWaalsContact O-CB 3.31Å; E170-D173 WeakPolarHBondContact O-CB 3.26Å; E170-D173 PolarHBondContact O-N 2.75Å; D173-N177 HydrophobicContact CB-CB 4.25Å; D173-N177 PolarHBondContact OD1-ND2 2.9Å; D173-N177 VanDerWaalsContact OD1-ND2 3.15Å; D173-V178 HydrophobicContact CB-CG2 4.37Å; D173-K181 WeakPolarHBondContact OD2-CE 3.47Å; D173-K181 IonicContact OD2-NZ 3.26Å; D173-K181 PolarHBondContact OD2-NZ 3.42Å; D173-T221 CarbonylContact O-C 3.53Å; D173-T221 VanDerWaalsContact O-CA 3.23Å; D173-T221 WeakPolarHBondContact O-CA 3.42Å; D173-L222 HydrophobicContact CB-CD1 4.29Å; D173-L222 PolarHBondContact O-N 3.43Å
174T94.4Very high89.1Confident33 Ų3340.7 Ų40.720%0.20223%0.227CC..BIsolated β-bridgetrans-72.7160.317262.60000111S172 D176 N177 V178 R220 T221S172-T174 PolarHBondContact O-N 3.25Å; T174-D176 PolarHBondContact O-N 2.85Å; T174-N177 WeakPolarHBondContact O-CB 3.21Å; T174-N177 PolarHBondContact O-N 3.04Å; T174-N177 VanDerWaalsContact O-N 3.1Å; T174-N177 VanDerWaalsContact OG1-CG 3.23Å; T174-N177 PolarHBondContact OG1-N 2.83Å; T174-N177 PolarHBondContact OG1-OD1 2.83Å; T174-N177 VanDerWaalsContact OG1-OD1 3.11Å; T174-V178 WeakPolarHBondContact O-CG2 3.3Å; T174-V178 PolarHBondContact O-N 2.77Å; T174-R220 CarbonylContact C-O 3.59Å; T174-R220 WeakPolarHBondContact CA-O 3.19Å; T174-T221 HydrophobicContact CG2-CG2 4.39Å
175I94.6Very high88.9Confident0 Ų043.5 Ų43.50%023%0.233CC..Hα-helixtrans-59.8-32.4173.6-58.7-51.7000111.3V178 K179 L195 L216 E217 R220 L222 Y225I175-V178 PolarHBondContact O-N 2.83Å; I175-K179 HydrophobicContact CG2-CD 4.49Å; I175-K179 WeakPolarHBondContact O-CG 3.49Å; I175-K179 PolarHBondContact O-N 2.88Å; I175-L195 HydrophobicContact CG2-CD1 4.18Å; I175-L216 HydrophobicContact CD1-CB 3.89Å; I175-L216 HydrophobicContact CD1-CD1 3.68Å; I175-L216 HydrophobicContact CD1-CG 4.31Å; I175-L216 HydrophobicContact CG1-CB 3.92Å; I175-L216 HydrophobicContact CG2-CB 4.05Å; I175-E217 WeakPolarHBondContact CB-O 3.2Å; I175-E217 VanDerWaalsContact CG1-O 3.25Å; I175-E217 WeakPolarHBondContact CG1-O 3.17Å; I175-R220 WeakPolarHBondContact CG1-O 3.42Å; I175-R220 PolarHBondContact N-O 2.94Å; I175-L222 HydrophobicContact CD1-CD2 4.12Å; I175-Y225 HydrophobicContact CD1-CD2 4.28Å; I175-Y225 HydrophobicContact CD1-CE2 4.26Å; I175-Y225 HydrophobicContact CG1-CE2 4.07Å
176D93.3Very high89Confident60 Ų6046.1 Ų46.132%0.32125%0.246SC..Hα-helixtrans-61-47.9172-58.2-79.1000111.7T174 V178 K179 T180 D218 G219T174-D176 PolarHBondContact O-N 2.85Å; D176-V178 VanDerWaalsContact C-N 3.28Å; D176-V178 PolarHBondContact O-N 3.27Å; D176-K179 WeakPolarHBondContact O-CB 3.47Å; D176-K179 PolarHBondContact O-N 2.83Å; D176-K179 VanDerWaalsContact O-N 3.08Å; D176-T180 PolarHBondContact O-N 2.9Å; D176-T180 PolarHBondContact O-OG1 3.08Å; D176-D218 WeakPolarHBondContact OD1-CB 3.12Å; D176-G219 PolarHBondContact OD2-N 3.47Å
177N91.4Very high88.8Confident70 Ų7046.5 Ų46.537%0.37426%0.26SS..Hα-helixtrans-57.7-43.6176.1-65.3-0.6000111.1D173 T174 K179 T180 K181D173-N177 HydrophobicContact CB-CB 4.25Å; D173-N177 PolarHBondContact OD1-ND2 2.9Å; D173-N177 VanDerWaalsContact OD1-ND2 3.15Å; T174-N177 WeakPolarHBondContact O-CB 3.21Å; T174-N177 PolarHBondContact O-N 3.04Å; T174-N177 VanDerWaalsContact O-N 3.1Å; T174-N177 VanDerWaalsContact OG1-CG 3.23Å; T174-N177 PolarHBondContact OG1-N 2.83Å; T174-N177 PolarHBondContact OG1-OD1 2.83Å; T174-N177 VanDerWaalsContact OG1-OD1 3.11Å; N177-K179 VanDerWaalsContact C-N 3.31Å; N177-K179 PolarHBondContact O-N 3.11Å; N177-T180 PolarHBondContact O-N 2.91Å; N177-K181 WeakPolarHBondContact O-CG 3.42Å; N177-K181 PolarHBondContact O-N 2.96Å
178V93.4Very high88.6Confident0 Ų047.7 Ų47.70%027%0.266CS..Hα-helixtrans-62.3-41.1178.2178.30000110.8I155 L167 V169 D173 T174 I175 D176 K181 I182 L195 L222I155-V178 HydrophobicContact CD1-CG1 4.24Å; L167-V178 HydrophobicContact CD1-CG1 3.9Å; V169-V178 HydrophobicContact CG1-CG2 4.3Å; D173-V178 HydrophobicContact CB-CG2 4.37Å; T174-V178 WeakPolarHBondContact O-CG2 3.3Å; T174-V178 PolarHBondContact O-N 2.77Å; I175-V178 PolarHBondContact O-N 2.83Å; D176-V178 VanDerWaalsContact C-N 3.28Å; D176-V178 PolarHBondContact O-N 3.27Å; V178-K181 PolarHBondContact O-N 3.37Å; V178-I182 HydrophobicContact CG1-CD1 4.29Å; V178-I182 WeakPolarHBondContact O-CG1 3.29Å; V178-I182 PolarHBondContact O-N 3.18Å; V178-L195 HydrophobicContact CB-CD1 4.37Å; V178-L195 HydrophobicContact CG1-CD1 3.8Å; V178-L222 HydrophobicContact CG2-CD1 4.14Å; V178-L222 HydrophobicContact CG2-CD2 3.94Å; V178-L222 HydrophobicContact CG2-CG 4.11Å
179K94.3Very high88.6Confident7 Ų745.8 Ų45.83%0.0326%0.259CS..Hα-helixtrans-65.3-41.2176.3-71.8171.1166.8-173.80112.4I175 D176 N177 K181 I182 Q183 P190 Q193 L195 D218I175-K179 HydrophobicContact CG2-CD 4.49Å; I175-K179 WeakPolarHBondContact O-CG 3.49Å; I175-K179 PolarHBondContact O-N 2.88Å; D176-K179 WeakPolarHBondContact O-CB 3.47Å; D176-K179 PolarHBondContact O-N 2.83Å; D176-K179 VanDerWaalsContact O-N 3.08Å; N177-K179 VanDerWaalsContact C-N 3.31Å; N177-K179 PolarHBondContact O-N 3.11Å; K179-K181 VanDerWaalsContact C-N 3.34Å; K179-K181 PolarHBondContact O-N 3.19Å; K179-I182 WeakPolarHBondContact O-CB 3.46Å; K179-I182 PolarHBondContact O-N 3.16Å; K179-I182 VanDerWaalsContact O-N 3.12Å; K179-Q183 PolarHBondContact O-N 2.98Å; K179-P190 HydrophobicContact CB-CB 3.86Å; K179-P190 HydrophobicContact CB-CG 4.41Å; K179-P190 HydrophobicContact CD-CB 4.24Å; K179-P190 PolarHBondContact NZ-O 3.08Å; K179-Q193 HydrophobicContact CD-CB 4.4Å; K179-Q193 VanDerWaalsContact CE-O 3.32Å; K179-Q193 WeakPolarHBondContact CE-O 3.49Å; K179-Q193 HydrophobicContact CG-CB 4.09Å; K179-Q193 PolarHBondContact NZ-O 3.38Å; K179-Q193 PolarHBondContact O-NE2 3.3Å; K179-Q193 PolarHBondContact O-OE1 2.88Å; K179-L195 HydrophobicContact CG-CD1 4.03Å; K179-D218 WeakPolarHBondContact CE-OD1 3.45Å; K179-D218 IonicContact NZ-OD1 3.46Å; K179-D218 PolarHBondContact NZ-OD1 3.3Å; K179-D218 IonicContact NZ-OD2 3.03Å; K179-D218 PolarHBondContact NZ-OD2 3.32Å
180T90.3Very high88.6Confident60 Ų6047.1 Ų47.137%0.36827%0.267SS..Hα-helixtrans-59.9-44.7173.1-55.70000110.8D176 N177 I182 Q183 D184D176-T180 PolarHBondContact O-N 2.9Å; D176-T180 PolarHBondContact O-OG1 3.08Å; N177-T180 PolarHBondContact O-N 2.91Å; T180-I182 PolarHBondContact O-N 3.4Å; T180-Q183 CarbonylContact O-C 3.59Å; T180-Q183 WeakPolarHBondContact O-CA 3.45Å; T180-Q183 WeakPolarHBondContact O-CB 3.04Å; T180-Q183 PolarHBondContact O-N 3.2Å; T180-D184 VanDerWaalsContact O-CG 3.25Å; T180-D184 PolarHBondContact O-N 3.15Å
181K90.2Very high88.6Confident53 Ų5347 Ų4723%0.2327%0.268CS..Hα-helixtrans-60.9-30.9174.8-67.2-178.8-164.9-150.80113.2L167 E168 V169 D173 N177 V178 K179 K185L167-K181 HydrophobicContact CD2-CB 4.23Å; E168-K181 WeakPolarHBondContact O-CD 3.42Å; E168-K181 PolarHBondContact O-NZ 2.94Å; V169-K181 HydrophobicContact CG1-CD 4.24Å; D173-K181 WeakPolarHBondContact OD2-CE 3.47Å; D173-K181 IonicContact OD2-NZ 3.26Å; D173-K181 PolarHBondContact OD2-NZ 3.42Å; N177-K181 WeakPolarHBondContact O-CG 3.42Å; N177-K181 PolarHBondContact O-N 2.96Å; V178-K181 PolarHBondContact O-N 3.37Å; K179-K181 VanDerWaalsContact C-N 3.34Å; K179-K181 PolarHBondContact O-N 3.19Å; K181-K185 PolarHBondContact O-N 3.32Å
182I91.1Very high88.5Confident0 Ų046 Ų460%026%0.258CS..Hα-helixtrans-72.4-42.8172.5-65.5163.6000110.4V157 L167 V178 K179 T180 D184 K185 E186 Q193 L195 L235V157-I182 HydrophobicContact CG1-CD1 4.15Å; V157-I182 HydrophobicContact CG2-CD1 4.15Å; L167-I182 HydrophobicContact CD1-CD1 4.19Å; L167-I182 HydrophobicContact CD1-CG1 3.63Å; L167-I182 HydrophobicContact CD2-CG1 4.47Å; V178-I182 HydrophobicContact CG1-CD1 4.29Å; V178-I182 WeakPolarHBondContact O-CG1 3.29Å; V178-I182 PolarHBondContact O-N 3.18Å; K179-I182 WeakPolarHBondContact O-CB 3.46Å; K179-I182 PolarHBondContact O-N 3.16Å; K179-I182 VanDerWaalsContact O-N 3.12Å; T180-I182 PolarHBondContact O-N 3.4Å; I182-D184 VanDerWaalsContact C-N 3.32Å; I182-D184 PolarHBondContact O-N 3.32Å; I182-K185 PolarHBondContact O-N 3.48Å; I182-E186 HydrophobicContact CG2-CB 4.5Å; I182-E186 WeakPolarHBondContact O-CB 3.46Å; I182-E186 PolarHBondContact O-N 2.74Å; I182-Q193 VanDerWaalsContact CD1-OE1 3.27Å; I182-L195 HydrophobicContact CD1-CD1 4.05Å; I182-L195 HydrophobicContact CD1-CD2 3.79Å; I182-L195 HydrophobicContact CD1-CG 4.39Å; I182-L235 HydrophobicContact CG2-CD2 4.11Å
183Q89.7Confident88.7Confident51 Ų5142.5 Ų42.524%0.23823%0.234CC..Hα-helixtrans-57.4-46.8175.1-177.4-179.217.400110.6K179 T180 K185 E186 G187 I188 P190K179-Q183 PolarHBondContact O-N 2.98Å; T180-Q183 CarbonylContact O-C 3.59Å; T180-Q183 WeakPolarHBondContact O-CA 3.45Å; T180-Q183 WeakPolarHBondContact O-CB 3.04Å; T180-Q183 PolarHBondContact O-N 3.2Å; Q183-K185 VanDerWaalsContact C-N 3.26Å; Q183-K185 PolarHBondContact O-N 3.47Å; Q183-E186 PolarHBondContact O-N 3.03Å; Q183-G187 WeakPolarHBondContact O-CA 3.4Å; Q183-G187 PolarHBondContact O-N 2.69Å; Q183-I188 VanDerWaalsContact CA-O 3.29Å; Q183-I188 WeakPolarHBondContact CA-O 3.21Å; Q183-I188 VanDerWaalsContact CB-O 3.23Å; Q183-I188 WeakPolarHBondContact CB-O 3.46Å; Q183-P190 HydrophobicContact CB-CG 4.47Å
184D82.1Confident88.6Confident123 Ų12346.3 Ų46.366%0.65825%0.247SC*.Hα-helixtrans-61.8-34.1-179.9-63.8-25.7000112.6T180 I182T180-D184 VanDerWaalsContact O-CG 3.25Å; T180-D184 PolarHBondContact O-N 3.15Å; I182-D184 VanDerWaalsContact C-N 3.32Å; I182-D184 PolarHBondContact O-N 3.32Å
185K82.3Confident88.5Confident125 Ų12544.8 Ų44.854%0.54324%0.237SC..Hα-helixtrans-86.6-34.2179.9-77.7-159.1178.4-167.50114.6I165 T166 L167 K181 I182 Q183I165-K185 HydrophobicContact CG2-CD 4.16Å; T166-K185 PolarHBondContact O-NZ 3.19Å; L167-K185 HydrophobicContact CD2-CD 3.97Å; K181-K185 PolarHBondContact O-N 3.32Å; I182-K185 PolarHBondContact O-N 3.48Å; Q183-K185 VanDerWaalsContact C-N 3.26Å; Q183-K185 PolarHBondContact O-N 3.47Å
186E88Confident88.2Confident62 Ų6245.6 Ų45.629%0.2924%0.242SC..Hα-helixtrans-122.6-5.9-166.6-63.3-72142.200113.4K163 I165 I182 Q183 I188K163-E186 VanDerWaalsContact CE-OE1 3.3Å; K163-E186 WeakPolarHBondContact CE-OE1 3.38Å; K163-E186 WeakPolarHBondContact CE-OE2 3.3Å; K163-E186 IonicContact NZ-OE1 2.69Å; K163-E186 PolarHBondContact NZ-OE1 3.15Å; K163-E186 IonicContact NZ-OE2 3.15Å; K163-E186 PolarHBondContact NZ-OE2 3.49Å; I165-E186 HydrophobicContact CD1-CG 3.63Å; I165-E186 HydrophobicContact CG1-CG 4Å; I182-E186 HydrophobicContact CG2-CB 4.5Å; I182-E186 WeakPolarHBondContact O-CB 3.46Å; I182-E186 PolarHBondContact O-N 2.74Å; Q183-E186 PolarHBondContact O-N 3.03Å; E186-I188 HydrophobicContact CB-CD1 3.74Å; E186-I188 HydrophobicContact CB-CG1 3.97Å; E186-I188 PolarHBondContact O-N 3.29Å
187G82.9Confident88Confident61 Ų6144 Ų4463%0.62923%0.232SC*.  trans71.413-17800000114.5Q183 P189Q183-G187 WeakPolarHBondContact O-CA 3.4Å; Q183-G187 PolarHBondContact O-N 2.69Å; G187-P189 WeakPolarHBondContact O-CD 3.41Å
188I84.2Confident86.8Confident27 Ų2742.6 Ų42.614%0.13823%0.23CC..  trans-90.3118.3-175.2-56.8164.8000109.4Q183 E186 Q192 Q193 L235 L237Q183-I188 VanDerWaalsContact CA-O 3.29Å; Q183-I188 WeakPolarHBondContact CA-O 3.21Å; Q183-I188 VanDerWaalsContact CB-O 3.23Å; Q183-I188 WeakPolarHBondContact CB-O 3.46Å; E186-I188 HydrophobicContact CB-CD1 3.74Å; E186-I188 HydrophobicContact CB-CG1 3.97Å; E186-I188 PolarHBondContact O-N 3.29Å; I188-Q192 HydrophobicContact CG2-CB 4.37Å; I188-Q193 HydrophobicContact CB-CG 4.41Å; I188-Q193 HydrophobicContact CG2-CG 3.68Å; I188-Q193 PolarHBondContact O-NE2 2.84Å; I188-L235 HydrophobicContact CD1-CD2 4.01Å; I188-L237 HydrophobicContact CD1-CD2 4.15Å; I188-L237 HydrophobicContact CG2-CD2 3.63Å
189P84.5Confident85.2Confident20 Ų2044.6 Ų44.613%0.1325%0.251CS..  trans-56.9138.2177.8-30.939.9000114.1G187 D191 Q192 Q193 E260G187-P189 WeakPolarHBondContact O-CD 3.41Å; P189-D191 VanDerWaalsContact C-N 3.26Å; P189-D191 WeakPolarHBondContact CB-OD1 3.41Å; P189-D191 PolarHBondContact O-N 3.27Å; P189-Q192 HydrophobicContact CB-CG 4.26Å; P189-Q192 WeakPolarHBondContact O-CB 3.45Å; P189-Q192 PolarHBondContact O-N 3.37Å; P189-Q193 WeakPolarHBondContact O-CG 3.08Å; P189-Q193 PolarHBondContact O-N 2.72Å; P189-E260 WeakPolarHBondContact CB-OE1 3.21Å
190P87.8Confident82.9Confident28 Ų2854.3 Ų54.318%0.18229%0.293CS..G310 helixtrans-56.2-32-177-30.137.4000115.3K179 Q183 Q192 Q193K179-P190 HydrophobicContact CB-CB 3.86Å; K179-P190 HydrophobicContact CB-CG 4.41Å; K179-P190 HydrophobicContact CD-CB 4.24Å; K179-P190 PolarHBondContact NZ-O 3.08Å; Q183-P190 HydrophobicContact CB-CG 4.47Å; P190-Q192 VanDerWaalsContact C-N 3.33Å; P190-Q193 WeakPolarHBondContact O-CB 3.36Å; P190-Q193 PolarHBondContact O-N 2.83Å
191D83.4Confident80.3Confident52 Ų5261.9 Ų61.928%0.27832%0.315SS..G310 helixtrans-71.1-26.6178.462.9-13.4000113.2P189 Q193 G242P189-D191 VanDerWaalsContact C-N 3.26Å; P189-D191 WeakPolarHBondContact CB-OD1 3.41Å; P189-D191 PolarHBondContact O-N 3.27Å; D191-Q193 VanDerWaalsContact C-N 3.31Å; D191-G242 WeakPolarHBondContact OD2-CA 3.42Å
192Q85.4Confident77.4Confident45 Ų4567.3 Ų67.321%0.2135%0.346CS..G310 helixtrans-80.6-14.4171.7-63.3-175.86.700112.5I188 P189 P190 L237 R238I188-Q192 HydrophobicContact CG2-CB 4.37Å; P189-Q192 HydrophobicContact CB-CG 4.26Å; P189-Q192 WeakPolarHBondContact O-CB 3.45Å; P189-Q192 PolarHBondContact O-N 3.37Å; P190-Q192 VanDerWaalsContact C-N 3.33Å; Q192-L237 CarbonylContact O-C 3.57Å; Q192-L237 WeakPolarHBondContact O-CA 3.28Å; Q192-R238 PolarHBondContact O-N 3.48Å
193Q89.7Confident74.7Confident0 Ų070.8 Ų70.80%037%0.374CS..EExtended strand (participates in β ladder)trans-88.3127.6-177.4-60.7177.837.800111.9K179 I182 I188 P189 P190 D191 L235K179-Q193 HydrophobicContact CD-CB 4.4Å; K179-Q193 VanDerWaalsContact CE-O 3.32Å; K179-Q193 WeakPolarHBondContact CE-O 3.49Å; K179-Q193 HydrophobicContact CG-CB 4.09Å; K179-Q193 PolarHBondContact NZ-O 3.38Å; K179-Q193 PolarHBondContact O-NE2 3.3Å; K179-Q193 PolarHBondContact O-OE1 2.88Å; I182-Q193 VanDerWaalsContact CD1-OE1 3.27Å; I188-Q193 HydrophobicContact CB-CG 4.41Å; I188-Q193 HydrophobicContact CG2-CG 3.68Å; I188-Q193 PolarHBondContact O-NE2 2.84Å; P189-Q193 WeakPolarHBondContact O-CG 3.08Å; P189-Q193 PolarHBondContact O-N 2.72Å; P190-Q193 WeakPolarHBondContact O-CB 3.36Å; P190-Q193 PolarHBondContact O-N 2.83Å; D191-Q193 VanDerWaalsContact C-N 3.31Å; Q193-L235 HydrophobicContact CB-CD1 3.71Å; Q193-L235 HydrophobicContact CG-CD1 3.92Å
194R88.2Confident72.2Confident95 Ų9576.3 Ų76.336%0.35840%0.402SS..EExtended strand (participates in β ladder)trans-120.3109.6168.5-144179.9-173.2-170.31.6108.8Q215 V236 R238R194-Q215 HydrophobicContact CG-CG 4.18Å; R194-V236 HydrophobicContact CB-CB 4.33Å; R194-V236 VanDerWaalsContact CB-O 3.24Å; R194-V236 WeakPolarHBondContact CB-O 3.42Å; R194-V236 PolarHBondContact N-O 3.24Å; R194-V236 PolarHBondContact O-N 3.38Å; R194-R238 HydrophobicContact CB-CG 4.5Å
195L91.3Very high70.3Confident1 Ų176 Ų761%0.00540%0.4CS..EExtended strand (participates in β ladder)trans-92.4132.6178.9-68.5173.7000110.5V157 I175 V178 K179 I182 L216 L233 L235V157-L195 HydrophobicContact CG1-CD2 4.03Å; I175-L195 HydrophobicContact CG2-CD1 4.18Å; V178-L195 HydrophobicContact CB-CD1 4.37Å; V178-L195 HydrophobicContact CG1-CD1 3.8Å; K179-L195 HydrophobicContact CG-CD1 4.03Å; I182-L195 HydrophobicContact CD1-CD1 4.05Å; I182-L195 HydrophobicContact CD1-CD2 3.79Å; I182-L195 HydrophobicContact CD1-CG 4.39Å; L195-L216 HydrophobicContact CB-CB 4.24Å; L195-L216 HydrophobicContact CB-CD1 3.96Å; L195-L216 HydrophobicContact CB-CG 4.32Å; L195-L216 PolarHBondContact O-N 3.3Å; L195-L233 HydrophobicContact CB-CD2 4.48Å; L195-L233 HydrophobicContact CD1-CD2 4.29Å; L195-L233 HydrophobicContact CD2-CD2 4.46Å; L195-L235 HydrophobicContact CD2-CB 4.29Å; L195-L235 HydrophobicContact CD2-CD1 4.07Å
196I89.6Confident68.9Low18 Ų1876.2 Ų76.29%0.09241%0.405CS..EExtended strand (participates in β ladder)trans-125.1131.4-179.6-61.2166.2000107.8I210 H234 V236I196-I210 HydrophobicContact CD1-CG2 3.54Å; I196-H234 HydrophobicContact CB-CB 4.49Å; I196-H234 PolarHBondContact N-O 2.92Å; I196-H234 PolarHBondContact O-N 3Å; I196-V236 HydrophobicContact CD1-CB 4.46Å; I196-V236 HydrophobicContact CD1-CG2 3.69Å
197F87.9Confident67.2Low27 Ų2779.8 Ų79.812%0.11842%0.422CS..EExtended strand (participates in β ladder)trans-123.7120.5172.8-175-122.3000109.4K214 L216 I227 L233F197-K214 PolarHBondContact N-O 3Å; F197-K214 PolarHBondContact O-N 3.39Å; F197-L216 HydrophobicContact CB-CD1 4.14Å; F197-L216 HydrophobicContact CB-CD2 3.71Å; F197-L216 HydrophobicContact CB-CG 4.13Å; F197-I227 HydrophobicContact CB-CD1 4.4Å; F197-I227 HydrophobicContact CD1-CD1 4.14Å; F197-I227 HydrophobicContact CD1-CG1 3.6Å; F197-I227 HydrophobicContact CD2-CG1 4.3Å; F197-I227 HydrophobicContact CE1-CG1 3.6Å; F197-I227 HydrophobicContact CE2-CG1 4.32Å; F197-I227 HydrophobicContact CG-CD1 4.16Å; F197-I227 HydrophobicContact CG-CG1 3.96Å; F197-I227 HydrophobicContact CZ-CG1 3.98Å; F197-L233 HydrophobicContact CD2-CG 4.43Å
198A67.5Low65.5Low39 Ų3981.6 Ų81.632%0.32242%0.417SS..  trans-106115.9168.300000106.8
199G59.8Low63.8Low43 Ų4384.8 Ų84.844%0.44343%0.427SS..  trans-54.7167.5170.800000111.9W201G199-W201 PolarHBondContact O-N 3.44Å
200K45.8Very low62.2Low210 Ų21085 Ų8591%0.91343%0.427SS*.SBendtrans-54.499.3-178.2-91.4-178.3174.4174.30112.1
201W36.3Very low60.3Low220 Ų22090.6 Ų90.683%0.83346%0.455SS*.  trans-142.3151.6162.3-90.691.7000111.8G199 R209G199-W201 PolarHBondContact O-N 3.44Å; W201-R209 PolarHBondContact O-NH2 3.32Å
202L29.1Very low58.8Low167 Ų16795.1 Ų95.187%0.87448%0.478SS*.  trans-47.2129.5-164-126.681.2000114M204L202-M204 PolarHBondContact O-N 3.23Å
203A34.6Very low57.8Low73 Ų7393.9 Ų93.960%0.60348%0.477SS*.  trans-82.3107179.700000111
204M35.8Very low57.3Low166 Ų166100.2 Ų100.282%0.81851%0.505SS*.SBendtrans-138.1120.6151.8-122.3169.976.400108L202L202-M204 PolarHBondContact O-N 3.23Å
205L42.9Very low57.2Low118 Ų11899.2 Ų99.262%0.61850%0.504SS*.  trans68.4108-169.4-85.691000117.9H207 L208 R209L205-H207 VanDerWaalsContact C-N 3.33Å; L205-H207 PolarHBondContact O-N 2.97Å; L205-L208 HydrophobicContact CB-CB 3.91Å; L205-L208 PolarHBondContact O-N 3.13Å; L205-R209 WeakPolarHBondContact O-CB 3.28Å; L205-R209 PolarHBondContact O-N 2.96Å; L205-R209 VanDerWaalsContact O-N 3.08Å
206I52.9Low57.2Low128 Ų12899.3 Ų99.366%0.65650%0.504SS*.Hα-helixtrans-56.6-41.6172.5-66.4167.9000111.9R209I206-R209 PolarHBondContact O-N 2.75Å
207H52.6Low57.3Low138 Ų138103.2 Ų103.264%0.63952%0.522SS*.Hα-helixtrans-70.3-37.6-179.3-84.383000113.1L205 R209L205-H207 VanDerWaalsContact C-N 3.33Å; L205-H207 PolarHBondContact O-N 2.97Å; H207-R209 VanDerWaalsContact C-N 3.34Å
208L47.2Very low57.3Low99 Ų99105.8 Ų105.852%0.51854%0.537SS..Hα-helixtrans-74-28.9178.5-159.370.4000111.7L205 I210 L211L205-L208 HydrophobicContact CB-CB 3.91Å; L205-L208 PolarHBondContact O-N 3.13Å; L208-I210 PolarHBondContact O-N 3.47Å; L208-L211 PolarHBondContact O-N 2.71Å
209R48.4Very low58.2Low93 Ų93106.5 Ų106.535%0.35155%0.548SS..Hα-helixtrans-65.8-33.4-179.8-152.2173.8-169.6-159.82.1113.5W201 L205 I206 H207 L211 L212 G213W201-R209 PolarHBondContact O-NH2 3.32Å; L205-R209 WeakPolarHBondContact O-CB 3.28Å; L205-R209 PolarHBondContact O-N 2.96Å; L205-R209 VanDerWaalsContact O-N 3.08Å; I206-R209 PolarHBondContact O-N 2.75Å; H207-R209 VanDerWaalsContact C-N 3.34Å; R209-L211 VanDerWaalsContact C-N 3.34Å; R209-L212 PolarHBondContact O-N 3.38Å; R209-G213 PolarHBondContact O-N 3.08Å
210I50.7Low59.8Low25 Ų25109.4 Ų109.413%0.12855%0.546CS..Hα-helixtrans-67.2-37.8177.1-65175.2000110.8L160 I196 L208 L212 H234 V236L160-I210 HydrophobicContact CD2-CD1 3.24Å; L160-I210 HydrophobicContact CG-CD1 4.41Å; I196-I210 HydrophobicContact CD1-CG2 3.54Å; L208-I210 PolarHBondContact O-N 3.47Å; I210-L212 VanDerWaalsContact C-N 3.29Å; I210-L212 PolarHBondContact O-N 3.41Å; I210-H234 HydrophobicContact CG1-CB 4.5Å; I210-V236 HydrophobicContact CG2-CG2 3.73Å
211L48Very low62Low146 Ų146100.8 Ų100.876%0.76451%0.511SS*.Hα-helixtrans-69.3-22.6-180-92.8140.5000113.9L208 R209L208-L211 PolarHBondContact O-N 2.71Å; R209-L211 VanDerWaalsContact C-N 3.34Å
212L51.8Low64.6Low147 Ų14790.3 Ų90.377%0.7747%0.471SS*.Hα-helixtrans-103.2-8-179-68.9169.3000113.9R209 I210R209-L212 PolarHBondContact O-N 3.38Å; I210-L212 VanDerWaalsContact C-N 3.29Å; I210-L212 PolarHBondContact O-N 3.41Å
213G63.9Low67.4Low18 Ų1885.3 Ų85.319%0.18645%0.45CS..SBendtrans-72.3151.4179.400000112.5R209 Q215R209-G213 PolarHBondContact O-N 3.08Å; G213-Q215 PolarHBondContact O-N 2.94Å
214K78.9Confident70.1Confident134 Ų13486.5 Ų86.558%0.58345%0.447SS*.EExtended strand (participates in β ladder)trans-73.2122176-154177.2-176.6-174.70107.9F197 L216 Y225F197-K214 PolarHBondContact N-O 3Å; F197-K214 PolarHBondContact O-N 3.39Å; K214-L216 PolarHBondContact O-N 3.31Å; K214-Y225 HydrophobicContact CD-CD1 4.42Å; K214-Y225 HydrophobicContact CD-CE1 4.27Å
215Q86.8Confident72.7Confident73 Ų7379.8 Ų79.834%0.34141%0.412SS..EExtended strand (participates in β ladder)trans-66.4132.7170.9-173.4-172.1-24.400108.5R194 G213R194-Q215 HydrophobicContact CG-CG 4.18Å; G213-Q215 PolarHBondContact O-N 2.94Å
216L91.7Very high74.9Confident3 Ų379.3 Ų79.32%0.01641%0.41CS..PPolyproline II helixtrans-79.9126.6176.2-55.6-174.1000109.3I175 L195 F197 K214 Y225 I227 L233I175-L216 HydrophobicContact CD1-CB 3.89Å; I175-L216 HydrophobicContact CD1-CD1 3.68Å; I175-L216 HydrophobicContact CD1-CG 4.31Å; I175-L216 HydrophobicContact CG1-CB 3.92Å; I175-L216 HydrophobicContact CG2-CB 4.05Å; L195-L216 HydrophobicContact CB-CB 4.24Å; L195-L216 HydrophobicContact CB-CD1 3.96Å; L195-L216 HydrophobicContact CB-CG 4.32Å; L195-L216 PolarHBondContact O-N 3.3Å; F197-L216 HydrophobicContact CB-CD1 4.14Å; F197-L216 HydrophobicContact CB-CD2 3.71Å; F197-L216 HydrophobicContact CB-CG 4.13Å; K214-L216 PolarHBondContact O-N 3.31Å; L216-Y225 HydrophobicContact CB-CE2 4.32Å; L216-Y225 HydrophobicContact CD2-CD1 3.61Å; L216-Y225 HydrophobicContact CD2-CD2 3.68Å; L216-Y225 HydrophobicContact CD2-CE1 3.81Å; L216-Y225 HydrophobicContact CD2-CE2 3.86Å; L216-Y225 HydrophobicContact CD2-CG 3.55Å; L216-I227 HydrophobicContact CD1-CD1 3.86Å; L216-I227 HydrophobicContact CD2-CD1 4.36Å; L216-L233 HydrophobicContact CD1-CD2 3.45Å; L216-L233 VanDerWaalsContact CD1-CD2 3.45Å; L216-L233 HydrophobicContact CD1-CG 4.22Å
217E90.1Very high76.7Confident100 Ų10073.5 Ų73.547%0.46738%0.38SS..PPolyproline II helixtrans-87137.9176.7-61169.3178.400110.8I175 R220 Y225I175-E217 WeakPolarHBondContact CB-O 3.2Å; I175-E217 VanDerWaalsContact CG1-O 3.25Å; I175-E217 WeakPolarHBondContact CG1-O 3.17Å; E217-R220 HydrophobicContact CB-CG 4.44Å; E217-R220 IonicContact OE2-CZ 3.3Å; E217-R220 VanDerWaalsContact OE2-CZ 3.32Å; E217-R220 IonicContact OE2-NE 3.98Å; E217-R220 PolarHBondContact OE2-NE 3.45Å; E217-R220 IonicContact OE2-NH2 2.84Å; E217-R220 PolarHBondContact OE2-NH2 2.94Å; E217-Y225 VanDerWaalsContact CB-OH 3.32Å; E217-Y225 WeakPolarHBondContact CB-OH 3.44Å; E217-Y225 PolarHBondContact N-OH 3.09Å
218D87.7Confident78.3Confident81 Ų8172.5 Ų72.543%0.43338%0.376SS..THydrogen-bonded Turntrans-59.8150.8171.3-64.1-13.6000110.3D176 K179 R220D176-D218 WeakPolarHBondContact OD1-CB 3.12Å; K179-D218 WeakPolarHBondContact CE-OD1 3.45Å; K179-D218 IonicContact NZ-OD1 3.46Å; K179-D218 PolarHBondContact NZ-OD1 3.3Å; K179-D218 IonicContact NZ-OD2 3.03Å; K179-D218 PolarHBondContact NZ-OD2 3.32Å; D218-R220 PolarHBondContact O-N 2.91Å
219G87.8Confident80.2Confident54 Ų5473.4 Ų73.456%0.55738%0.376SS*.THydrogen-bonded Turntrans79.8-19.9-17500000115.9D176D176-G219 PolarHBondContact OD2-N 3.47Å
220R92.3Very high82Confident105 Ų10575.6 Ų75.640%0.39639%0.39SS..  trans-83.2154.7173.1-64.7-149.2-158.4-146.6-2.3111.8T174 I175 E217 D218 D224 Y225T174-R220 CarbonylContact C-O 3.59Å; T174-R220 WeakPolarHBondContact CA-O 3.19Å; I175-R220 WeakPolarHBondContact CG1-O 3.42Å; I175-R220 PolarHBondContact N-O 2.94Å; E217-R220 HydrophobicContact CB-CG 4.44Å; E217-R220 IonicContact OE2-CZ 3.3Å; E217-R220 VanDerWaalsContact OE2-CZ 3.32Å; E217-R220 IonicContact OE2-NE 3.98Å; E217-R220 PolarHBondContact OE2-NE 3.45Å; E217-R220 IonicContact OE2-NH2 2.84Å; E217-R220 PolarHBondContact OE2-NH2 2.94Å; D218-R220 PolarHBondContact O-N 2.91Å; R220-D224 HydrophobicContact CB-CB 4.29Å; R220-Y225 HydrophobicContact CB-CD2 4.42Å; R220-Y225 HydrophobicContact CB-CE2 3.55Å; R220-Y225 WeakPolarHBondContact CD-OH 3.11Å; R220-Y225 HydrophobicContact CG-CE2 4.3Å
221T92.1Very high83.9Confident28 Ų2875.3 Ų75.317%0.17239%0.39CS..BIsolated β-bridgetrans-91.2164.1179.666.40000112.8S172 D173 T174 S223 D224 Y225S172-T221 WeakPolarHBondContact O-CG2 3.48Å; D173-T221 CarbonylContact O-C 3.53Å; D173-T221 VanDerWaalsContact O-CA 3.23Å; D173-T221 WeakPolarHBondContact O-CA 3.42Å; T174-T221 HydrophobicContact CG2-CG2 4.39Å; T221-S223 PolarHBondContact O-N 2.87Å; T221-S223 PolarHBondContact OG1-OG 3.4Å; T221-D224 PolarHBondContact N-OD2 2.68Å; T221-D224 WeakPolarHBondContact O-CB 3.47Å; T221-D224 PolarHBondContact O-N 3.1Å; T221-D224 PolarHBondContact OG1-N 3.23Å; T221-D224 VanDerWaalsContact OG1-N 3.15Å; T221-D224 PolarHBondContact OG1-OD2 3.47Å; T221-Y225 WeakPolarHBondContact O-CD2 3.39Å
222L91.3Very high85.9Confident0 Ų070.7 Ų70.70%037%0.368CS..THydrogen-bonded Turntrans-58.7-37.4171-69.9-177.2000112.2M153 I155 V169 D173 I175 V178 Y225 N226 I227M153-L222 HydrophobicContact CE-CD1 4.18Å; I155-L222 HydrophobicContact CD1-CD1 4.22Å; I155-L222 HydrophobicContact CD1-CD2 4.37Å; V169-L222 HydrophobicContact CB-CD1 3.58Å; V169-L222 HydrophobicContact CG1-CD1 4.14Å; V169-L222 HydrophobicContact CG2-CD1 3.39Å; D173-L222 HydrophobicContact CB-CD1 4.29Å; D173-L222 PolarHBondContact O-N 3.43Å; I175-L222 HydrophobicContact CD1-CD2 4.12Å; V178-L222 HydrophobicContact CG2-CD1 4.14Å; V178-L222 HydrophobicContact CG2-CD2 3.94Å; V178-L222 HydrophobicContact CG2-CG 4.11Å; L222-Y225 PolarHBondContact O-N 2.95Å; L222-N226 PolarHBondContact O-N 3.09Å; L222-I227 HydrophobicContact CB-CB 4.2Å; L222-I227 HydrophobicContact CD2-CB 4.19Å; L222-I227 HydrophobicContact CD2-CD1 3.57Å; L222-I227 HydrophobicContact CD2-CG1 4.47Å; L222-I227 HydrophobicContact CD2-CG2 4.1Å; L222-I227 WeakPolarHBondContact O-CB 3.49Å; L222-I227 PolarHBondContact O-N 3.31Å
223S88.8Confident87.8Confident63 Ų6363.7 Ų63.744%0.44133%0.331SS..G310 helixtrans-67.3-33.4177.243.30000113.1P171 T221 Y225 N226P171-S223 VanDerWaalsContact O-CB 3.3Å; P171-S223 WeakPolarHBondContact O-CB 3.36Å; P171-S223 PolarHBondContact O-N 3.32Å; P171-S223 PolarHBondContact O-OG 3.47Å; T221-S223 PolarHBondContact O-N 2.87Å; T221-S223 PolarHBondContact OG1-OG 3.4Å; S223-Y225 PolarHBondContact O-N 3.19Å; S223-Y225 VanDerWaalsContact O-N 3.17Å; S223-N226 PolarHBondContact O-N 2.95Å
224D90.3Very high89Confident98 Ų9864.7 Ų64.752%0.52433%0.331SS..G310 helixtrans-58.7-29173.4-67.3-37.3000113.1R220 T221R220-D224 HydrophobicContact CB-CB 4.29Å; T221-D224 PolarHBondContact N-OD2 2.68Å; T221-D224 WeakPolarHBondContact O-CB 3.47Å; T221-D224 PolarHBondContact O-N 3.1Å; T221-D224 PolarHBondContact OG1-N 3.23Å; T221-D224 VanDerWaalsContact OG1-N 3.15Å; T221-D224 PolarHBondContact OG1-OD2 3.47Å
225Y90.4Very high89.5Confident24 Ų2458.5 Ų58.59%0.09430%0.304CS..G310 helixtrans-98.24.7176.6-65.8-75.5000113.5I175 K214 L216 E217 R220 T221 L222 S223 I227I175-Y225 HydrophobicContact CD1-CD2 4.28Å; I175-Y225 HydrophobicContact CD1-CE2 4.26Å; I175-Y225 HydrophobicContact CG1-CE2 4.07Å; K214-Y225 HydrophobicContact CD-CD1 4.42Å; K214-Y225 HydrophobicContact CD-CE1 4.27Å; L216-Y225 HydrophobicContact CB-CE2 4.32Å; L216-Y225 HydrophobicContact CD2-CD1 3.61Å; L216-Y225 HydrophobicContact CD2-CD2 3.68Å; L216-Y225 HydrophobicContact CD2-CE1 3.81Å; L216-Y225 HydrophobicContact CD2-CE2 3.86Å; L216-Y225 HydrophobicContact CD2-CG 3.55Å; E217-Y225 VanDerWaalsContact CB-OH 3.32Å; E217-Y225 WeakPolarHBondContact CB-OH 3.44Å; E217-Y225 PolarHBondContact N-OH 3.09Å; R220-Y225 HydrophobicContact CB-CD2 4.42Å; R220-Y225 HydrophobicContact CB-CE2 3.55Å; R220-Y225 WeakPolarHBondContact CD-OH 3.11Å; R220-Y225 HydrophobicContact CG-CE2 4.3Å; T221-Y225 WeakPolarHBondContact O-CD2 3.39Å; L222-Y225 PolarHBondContact O-N 2.95Å; S223-Y225 PolarHBondContact O-N 3.19Å; S223-Y225 VanDerWaalsContact O-N 3.17Å; Y225-I227 PolarHBondContact O-N 3.09Å
226N90.1Very high89.4Confident108 Ų10856.5 Ų56.558%0.57830%0.297SS*.THydrogen-bonded Turntrans50.840.4-173.4-16824.4000112.1L222 S223 Q228L222-N226 PolarHBondContact O-N 3.09Å; S223-N226 PolarHBondContact O-N 2.95Å; N226-Q228 PolarHBondContact O-N 2.93Å; N226-Q228 PolarHBondContact OD1-NE2 3.25Å; N226-Q228 VanDerWaalsContact OD1-NE2 3.09Å
227I89.2Confident88.9Confident6 Ų660.8 Ų60.83%0.03132%0.32CS..  trans-75.3122.1172-65.8169.4000106.4M153 I155 F197 L216 L222 Y225 L233M153-I227 HydrophobicContact CE-CG2 4.08Å; M153-I227 WeakPolarHBondContact CE-O 3.5Å; I155-I227 HydrophobicContact CG2-CG2 3.91Å; F197-I227 HydrophobicContact CB-CD1 4.4Å; F197-I227 HydrophobicContact CD1-CD1 4.14Å; F197-I227 HydrophobicContact CD1-CG1 3.6Å; F197-I227 HydrophobicContact CD2-CG1 4.3Å; F197-I227 HydrophobicContact CE1-CG1 3.6Å; F197-I227 HydrophobicContact CE2-CG1 4.32Å; F197-I227 HydrophobicContact CG-CD1 4.16Å; F197-I227 HydrophobicContact CG-CG1 3.96Å; F197-I227 HydrophobicContact CZ-CG1 3.98Å; L216-I227 HydrophobicContact CD1-CD1 3.86Å; L216-I227 HydrophobicContact CD2-CD1 4.36Å; L222-I227 HydrophobicContact CB-CB 4.2Å; L222-I227 HydrophobicContact CD2-CB 4.19Å; L222-I227 HydrophobicContact CD2-CD1 3.57Å; L222-I227 HydrophobicContact CD2-CG1 4.47Å; L222-I227 HydrophobicContact CD2-CG2 4.1Å; L222-I227 WeakPolarHBondContact O-CB 3.49Å; L222-I227 PolarHBondContact O-N 3.31Å; Y225-I227 PolarHBondContact O-N 3.09Å; I227-L233 HydrophobicContact CD1-CD1 4.46Å; I227-L233 HydrophobicContact CD1-CD2 4.29Å; I227-L233 HydrophobicContact CD1-CG 4.45Å; I227-L233 HydrophobicContact CG2-CD1 4.13Å
228Q87.2Confident88.2Confident117 Ų11760.5 Ų60.555%0.54731%0.314SS..  trans-110.9172.4-177.7-60.5-167.8-5.900111.3N226 E230 S231N226-Q228 PolarHBondContact O-N 2.93Å; N226-Q228 PolarHBondContact OD1-NE2 3.25Å; N226-Q228 VanDerWaalsContact OD1-NE2 3.09Å; Q228-E230 PolarHBondContact O-N 2.89Å; Q228-S231 PolarHBondContact N-OG 2.94Å; Q228-S231 WeakPolarHBondContact O-CB 3.38Å; Q228-S231 PolarHBondContact O-N 3.47Å; Q228-S231 PolarHBondContact O-OG 2.89Å
229K86.1Confident87.1Confident119 Ų11964.6 Ų64.652%0.51734%0.336SS..THydrogen-bonded Turntrans-49.8135.9172.4-166.8171.3-179.6163.80111M153 S231M153-K229 HydrophobicContact CG-CB 4.2Å; K229-S231 PolarHBondContact O-N 3.41Å
230E86.8Confident85.9Confident138 Ų13871.8 Ų71.865%0.64535%0.346SS*.THydrogen-bonded Turntrans65.711.1-175.1-56.5-170.8172.400116.2Q154 F156 Q228Q154-E230 WeakPolarHBondContact O-CA 3.28Å; Q154-E230 PolarHBondContact O-N 3.2Å; F156-E230 HydrophobicContact CE2-CB 3.89Å; F156-E230 HydrophobicContact CE2-CG 4.14Å; Q228-E230 PolarHBondContact O-N 2.89Å
231S90.8Very high84.2Confident20 Ų2068.5 Ų68.514%0.1435%0.345CS..  trans-61.5144.7172.6-66.80000111.5I155 F156 Q228 K229I155-S231 WeakPolarHBondContact CA-O 3.22Å; F156-S231 PolarHBondContact N-O 2.99Å; Q228-S231 PolarHBondContact N-OG 2.94Å; Q228-S231 WeakPolarHBondContact O-CB 3.38Å; Q228-S231 PolarHBondContact O-N 3.47Å; Q228-S231 PolarHBondContact O-OG 2.89Å; K229-S231 PolarHBondContact O-N 3.41Å
232T89.5Confident83.2Confident48 Ų4867.5 Ų67.529%0.29434%0.339SS..EExtended strand (participates in β ladder)trans-108.9116.1176.7-55.90000110.9F156 K158F156-T232 HydrophobicContact CB-CG2 4.35Å; F156-T232 CarbonylContact O-C 3.58Å; F156-T232 VanDerWaalsContact O-CA 3.27Å; F156-T232 WeakPolarHBondContact O-CA 3.28Å; K158-T232 HydrophobicContact CB-CG2 4.33Å; K158-T232 HydrophobicContact CD-CG2 4.02Å; K158-T232 HydrophobicContact CG-CG2 3.93Å
233L91.3Very high83Confident0 Ų068.8 Ų68.80%035%0.346CS..EExtended strand (participates in β ladder)trans-91.5155.5168.6-6672.6000109.4I155 F156 V157 K158 L195 F197 L216 I227I155-L233 HydrophobicContact CB-CD1 4.18Å; I155-L233 HydrophobicContact CD1-CD1 3.82Å; I155-L233 HydrophobicContact CD1-CD2 4.38Å; I155-L233 HydrophobicContact CG1-CD1 4.46Å; F156-L233 PolarHBondContact O-N 3.2Å; V157-L233 WeakPolarHBondContact CA-O 3.42Å; V157-L233 HydrophobicContact CG2-CB 4.38Å; K158-L233 PolarHBondContact N-O 3.28Å; L195-L233 HydrophobicContact CB-CD2 4.48Å; L195-L233 HydrophobicContact CD1-CD2 4.29Å; L195-L233 HydrophobicContact CD2-CD2 4.46Å; F197-L233 HydrophobicContact CD2-CG 4.43Å; L216-L233 HydrophobicContact CD1-CD2 3.45Å; L216-L233 VanDerWaalsContact CD1-CD2 3.45Å; L216-L233 HydrophobicContact CD1-CG 4.22Å; I227-L233 HydrophobicContact CD1-CD1 4.46Å; I227-L233 HydrophobicContact CD1-CD2 4.29Å; I227-L233 HydrophobicContact CD1-CG 4.45Å; I227-L233 HydrophobicContact CG2-CD1 4.13Å
234H89.3Confident83.1Confident39 Ų3967.3 Ų67.318%0.18133%0.332CS..EExtended strand (participates in β ladder)trans-113.3128.4175.2-66.937.2000109K158 I196 I210K158-H234 CarbonylContact O-C 3.6Å; K158-H234 WeakPolarHBondContact O-CA 3.44Å; I196-H234 HydrophobicContact CB-CB 4.49Å; I196-H234 PolarHBondContact N-O 2.92Å; I196-H234 PolarHBondContact O-N 3Å; I210-H234 HydrophobicContact CG1-CB 4.5Å
235L89.2Confident83.3Confident4 Ų462.7 Ų62.72%0.02131%0.307CS..EExtended strand (participates in β ladder)trans-96.3120.5176.7176.863.1000109.7V157 K158 T159 I182 I188 Q193 L195 L237V157-L235 HydrophobicContact CG1-CB 3.57Å; V157-L235 HydrophobicContact CG1-CD2 4.49Å; K158-L235 PolarHBondContact O-N 2.93Å; T159-L235 HydrophobicContact CG2-CD2 4.38Å; I182-L235 HydrophobicContact CG2-CD2 4.11Å; I188-L235 HydrophobicContact CD1-CD2 4.01Å; Q193-L235 HydrophobicContact CB-CD1 3.71Å; Q193-L235 HydrophobicContact CG-CD1 3.92Å; L195-L235 HydrophobicContact CD2-CB 4.29Å; L195-L235 HydrophobicContact CD2-CD1 4.07Å; L235-L237 HydrophobicContact CD1-CD2 4.33Å; L235-L237 HydrophobicContact CD2-CD2 4.1Å; L235-L237 HydrophobicContact CG-CD2 4.1Å
236V84.9Confident83.6Confident31 Ų3164.1 Ų64.119%0.18831%0.314CS..EExtended strand (participates in β ladder)trans-112.8123.81711800000108.1L160 R194 I196 I210L160-V236 HydrophobicContact CD1-CG1 4.34Å; L160-V236 HydrophobicContact CD1-CG2 4.45Å; R194-V236 HydrophobicContact CB-CB 4.33Å; R194-V236 VanDerWaalsContact CB-O 3.24Å; R194-V236 WeakPolarHBondContact CB-O 3.42Å; R194-V236 PolarHBondContact N-O 3.24Å; R194-V236 PolarHBondContact O-N 3.38Å; I196-V236 HydrophobicContact CD1-CB 4.46Å; I196-V236 HydrophobicContact CD1-CG2 3.69Å; I210-V236 HydrophobicContact CG2-CG2 3.73Å
237L82.2Confident84Confident94 Ų9459 Ų5949%0.49229%0.286SS..EExtended strand (participates in β ladder)trans-81.2130178.4-58.5-179.8000110.1I188 Q192 L235I188-L237 HydrophobicContact CD1-CD2 4.15Å; I188-L237 HydrophobicContact CG2-CD2 3.63Å; Q192-L237 CarbonylContact O-C 3.57Å; Q192-L237 WeakPolarHBondContact O-CA 3.28Å; L235-L237 HydrophobicContact CD1-CD2 4.33Å; L235-L237 HydrophobicContact CD2-CD2 4.1Å; L235-L237 HydrophobicContact CG-CD2 4.1Å
238R74.6Confident84.2Confident94 Ų9462.8 Ų62.836%0.35530%0.303SS..  trans-80.9129.5170.3-72.6-178.8150.6131.4-9.8109.1Q192 R194 R240Q192-R238 PolarHBondContact O-N 3.48Å; R194-R238 HydrophobicContact CB-CG 4.5Å; R238-R240 VanDerWaalsContact C-N 3.27Å; R238-R240 PolarHBondContact O-N 3.43Å
239L64.2Low84.3Confident167 Ų16758.3 Ų58.387%0.87428%0.284SS*.THydrogen-bonded Turntrans-70.4-21.4177-68.5168.8000113.4
240R62.7Low84.1Confident205 Ų20559.2 Ų59.277%0.77429%0.293SS*.THydrogen-bonded Turntrans-153.158.5-174.4-65.7-170.6-166.5-179.44.4113R238 E258R238-R240 VanDerWaalsContact C-N 3.27Å; R238-R240 PolarHBondContact O-N 3.43Å; R240-E258 WeakPolarHBondContact CA-OE1 3.32Å
241G58.2Low83.9Confident36 Ų3658.8 Ų58.837%0.37130%0.3SS..  trans-89.5-26.3-176.800000114.6
242G70.8Confident83.6Confident6 Ų660.4 Ų60.46%0.06232%0.32CS..SBendtrans-104.6-174.1-159.800000115.9D191 Q244 E258D191-G242 WeakPolarHBondContact OD2-CA 3.42Å; G242-Q244 PolarHBondContact O-N 3.24Å; G242-E258 WeakPolarHBondContact CA-OE2 3.24Å; G242-E258 PolarHBondContact N-OE2 3.15Å; G242-E258 VanDerWaalsContact N-OE2 3.1Å
243M87.2Confident83.7Confident28 Ų2863 Ų6314%0.13833%0.327CS..EExtended strand (participates in β ladder)trans-65.8117.7167.7169.6178.6159.700108.1I245 V259 P261 I303 K305M243-I245 HydrophobicContact CE-CG2 3.99Å; M243-V259 WeakPolarHBondContact CB-O 3.37Å; M243-V259 HydrophobicContact CE-CG2 4.3Å; M243-V259 HydrophobicContact CG-CG2 4.17Å; M243-V259 WeakPolarHBondContact O-CG2 3.47Å; M243-V259 PolarHBondContact O-N 2.84Å; M243-P261 HydrophobicContact SD-CG 3.81Å; M243-I303 HydrophobicContact CE-CG2 4.25Å; M243-I303 WeakPolarHBondContact CE-O 3.5Å; M243-K305 HydrophobicContact CG-CB 4.08Å
244Q90.6Very high83.7Confident32 Ų3266 Ų6615%0.1535%0.345CS..EExtended strand (participates in β ladder)trans-96.9142.9174.9-71.2173.712.700110.1G242 T256 L257 E258 E306G242-Q244 PolarHBondContact O-N 3.24Å; Q244-T256 HydrophobicContact CB-CG2 4.19Å; Q244-T256 HydrophobicContact CG-CG2 4.22Å; Q244-L257 CarbonylContact C-O 3.5Å; Q244-L257 VanDerWaalsContact CA-O 3.26Å; Q244-L257 WeakPolarHBondContact CA-O 3.28Å; Q244-E258 VanDerWaalsContact CD-OE1 3.29Å; Q244-E258 WeakPolarHBondContact CG-OE1 3.44Å; Q244-E258 PolarHBondContact NE2-OE1 3.48Å; Q244-E306 PolarHBondContact O-N 3.38Å
245I95.1Very high83.8Confident0 Ų064.4 Ų64.40%034%0.338CS..EExtended strand (participates in β ladder)trans-125.2158.7166.463172000109.7M243 L257 V259 V268 L298 I303 L309M243-I245 HydrophobicContact CE-CG2 3.99Å; I245-L257 HydrophobicContact CG1-CB 4.01Å; I245-L257 PolarHBondContact N-O 2.81Å; I245-L257 PolarHBondContact O-N 2.85Å; I245-V259 HydrophobicContact CB-CG2 4.32Å; I245-V259 HydrophobicContact CD1-CG1 3.9Å; I245-V259 HydrophobicContact CD1-CG2 4.03Å; I245-V259 HydrophobicContact CG1-CG1 4Å; I245-V259 HydrophobicContact CG1-CG2 3.82Å; I245-V259 HydrophobicContact CG2-CG2 3.74Å; I245-V268 HydrophobicContact CD1-CG1 4.26Å; I245-L298 HydrophobicContact CD1-CD1 4.29Å; I245-L298 HydrophobicContact CD1-CD2 4.36Å; I245-I303 HydrophobicContact CG2-CG2 3.91Å; I245-L309 HydrophobicContact CB-CD1 4.48Å; I245-L309 HydrophobicContact CD1-CD1 4.15Å; I245-L309 HydrophobicContact CD1-CD2 4.27Å
246F96.7Very high84Confident54 Ų5466.7 Ų66.724%0.23735%0.353CS..EExtended strand (participates in β ladder)trans-109137.9176.6-57.1-70.9000110.1T254 I255 T256 E306 S307 T308 L309F246-T254 HydrophobicContact CB-CG2 3.96Å; F246-T254 HydrophobicContact CD1-CG2 4.03Å; F246-T254 HydrophobicContact CG-CG2 4.33Å; F246-I255 CarbonylContact C-O 3.58Å; F246-I255 WeakPolarHBondContact CA-O 3.44Å; F246-T256 HydrophobicContact CD1-CG2 4.26Å; F246-T256 HydrophobicContact CE1-CG2 4Å; F246-T256 WeakPolarHBondContact CE1-OG1 3.27Å; F246-E306 HydrophobicContact CD2-CB 4.49Å; F246-E306 WeakPolarHBondContact CD2-O 3.49Å; F246-E306 HydrophobicContact CE2-CB 3.83Å; F246-E306 HydrophobicContact CE2-CG 3.9Å; F246-E306 HydrophobicContact CZ-CG 4.4Å; F246-S307 PolarHBondContact N-O 3.15Å; F246-T308 HydrophobicContact CB-CG2 4.43Å; F246-T308 CarbonylContact O-C 3.6Å; F246-T308 WeakPolarHBondContact O-CA 3.19Å; F246-L309 PolarHBondContact O-N 2.9Å
247V96.9Very high84.3Confident0 Ų065.3 Ų65.30%034%0.344CS..EExtended strand (participates in β ladder)trans-118.1113.8173.5-178.40000107.8I255 L257 I272 L285 L309 L311V247-I255 HydrophobicContact CB-CB 4.34Å; V247-I255 PolarHBondContact N-O 2.81Å; V247-I255 PolarHBondContact O-N 2.9Å; V247-L257 HydrophobicContact CG2-CD1 3.6Å; V247-L257 HydrophobicContact CG2-CG 4.25Å; V247-I272 HydrophobicContact CG1-CD1 4.2Å; V247-I272 HydrophobicContact CG2-CD1 4.2Å; V247-L285 HydrophobicContact CG1-CD2 4.09Å; V247-L309 CarbonylContact C-O 3.51Å; V247-L309 WeakPolarHBondContact CA-O 3.33Å; V247-L309 HydrophobicContact CG2-CB 4.38Å; V247-L311 HydrophobicContact CG1-CB 3.53Å; V247-L311 HydrophobicContact CG1-CD2 4.34Å; V247-L311 HydrophobicContact CG1-CG 4.5Å
248K95Very high84.6Confident87 Ų8762.3 Ų62.338%0.37833%0.328SS..EExtended strand (participates in β ladder)trans-96.5127.6176.8-76.8-171.1179.9-1790110.9K253 T254 T308 L309 H310 L311K248-K253 WeakPolarHBondContact CA-O 3.37Å; K248-T254 WeakPolarHBondContact CE-OG1 3.34Å; K248-T254 HydrophobicContact CG-CG2 4.14Å; K248-T254 WeakPolarHBondContact CG-OG1 3.44Å; K248-T308 HydrophobicContact CB-CG2 4.28Å; K248-T308 HydrophobicContact CD-CG2 3.84Å; K248-T308 HydrophobicContact CG-CG2 3.81Å; K248-L309 PolarHBondContact N-O 3.36Å; K248-H310 CarbonylContact O-C 3.57Å; K248-H310 WeakPolarHBondContact O-CA 3.33Å; K248-L311 PolarHBondContact O-N 3.3Å
249T89.5Confident85.4Confident23 Ų2358 Ų5814%0.14131%0.312CS..EExtended strand (participates in β ladder)trans-79.2163.6170.268.30000110.5T251 G252 K253 I255 L311T249-T251 PolarHBondContact O-N 3.34Å; T249-T251 PolarHBondContact OG1-N 2.93Å; T249-T251 PolarHBondContact OG1-OG1 2.9Å; T249-G252 PolarHBondContact O-N 3.14Å; T249-K253 HydrophobicContact CG2-CB 4.3Å; T249-K253 PolarHBondContact N-O 2.61Å; T249-K253 WeakPolarHBondContact OG1-CB 3.42Å; T249-K253 PolarHBondContact OG1-N 2.85Å; T249-K253 VanDerWaalsContact OG1-N 3.17Å; T249-K253 PolarHBondContact OG1-O 2.74Å; T249-I255 HydrophobicContact CG2-CD1 4.13Å; T249-L311 HydrophobicContact CG2-CD2 4.44Å
250L81.4Confident86.5Confident138 Ų13851.8 Ų51.872%0.72328%0.278SS*.THydrogen-bonded Turntrans-62.6-21172-65.8176.2000113.5G252 V312L250-G252 PolarHBondContact O-N 3.06Å; L250-V312 HydrophobicContact CD1-CG1 4.32Å; L250-V312 HydrophobicContact CD1-CG2 4.43Å; L250-V312 HydrophobicContact CD2-CG2 4.41Å
251T82.6Confident87.9Confident129 Ų12945.2 Ų45.279%0.79126%0.262SS*.THydrogen-bonded Turntrans-78.5-5.9174.559.90000113T249T249-T251 PolarHBondContact O-N 3.34Å; T249-T251 PolarHBondContact OG1-N 2.93Å; T249-T251 PolarHBondContact OG1-OG1 2.9Å
252G83.7Confident89.5Confident53 Ų5346.9 Ų46.955%0.54627%0.268SS..SBendtrans89.6-4-177.700000114.5T249 L250 T254T249-G252 PolarHBondContact O-N 3.14Å; L250-G252 PolarHBondContact O-N 3.06Å; G252-T254 PolarHBondContact O-N 2.92Å
253K90.7Very high90.5Very high102 Ų10247.4 Ų47.444%0.44327%0.269SS..  trans-64132.9173.7-174.1-179.7175.4-1730109.3K248 T249 E276K248-K253 WeakPolarHBondContact CA-O 3.37Å; T249-K253 HydrophobicContact CG2-CB 4.3Å; T249-K253 PolarHBondContact N-O 2.61Å; T249-K253 WeakPolarHBondContact OG1-CB 3.42Å; T249-K253 PolarHBondContact OG1-N 2.85Å; T249-K253 VanDerWaalsContact OG1-N 3.17Å; T249-K253 PolarHBondContact OG1-O 2.74Å; K253-E276 WeakPolarHBondContact CE-OE1 3.11Å; K253-E276 IonicContact NZ-OE1 2.99Å; K253-E276 PolarHBondContact NZ-OE1 2.81Å; K253-E276 IonicContact NZ-OE2 2.73Å; K253-E276 PolarHBondContact NZ-OE2 2.92Å
254T92.4Very high90.9Very high63 Ų6347.8 Ų47.839%0.38727%0.273SS..EExtended strand (participates in β ladder)trans-108.9125.8176.3-54.90000109.4F246 K248 G252F246-T254 HydrophobicContact CB-CG2 3.96Å; F246-T254 HydrophobicContact CD1-CG2 4.03Å; F246-T254 HydrophobicContact CG-CG2 4.33Å; K248-T254 WeakPolarHBondContact CE-OG1 3.34Å; K248-T254 HydrophobicContact CG-CG2 4.14Å; K248-T254 WeakPolarHBondContact CG-OG1 3.44Å; G252-T254 PolarHBondContact O-N 2.92Å
255I92.1Very high91.2Very high7 Ų746.3 Ų46.34%0.03627%0.266CS..EExtended strand (participates in β ladder)trans-108.2130177.4-55.1150.3000107.4F246 V247 T249 L257 K275 E276F246-I255 CarbonylContact C-O 3.58Å; F246-I255 WeakPolarHBondContact CA-O 3.44Å; V247-I255 HydrophobicContact CB-CB 4.34Å; V247-I255 PolarHBondContact N-O 2.81Å; V247-I255 PolarHBondContact O-N 2.9Å; T249-I255 HydrophobicContact CG2-CD1 4.13Å; I255-L257 HydrophobicContact CG2-CD2 4.1Å; I255-L257 HydrophobicContact CG2-CG 4.49Å; I255-K275 HydrophobicContact CG2-CD 4.22Å; I255-E276 HydrophobicContact CD1-CG 3.62Å; I255-E276 HydrophobicContact CG1-CG 4.03Å; I255-E276 HydrophobicContact CG2-CG 4.43Å
256T92.8Very high91.2Very high52 Ų5251.6 Ų51.632%0.31929%0.291SS..EExtended strand (participates in β ladder)trans-96.1129174.3-54.30000109.6Q244 F246 K275Q244-T256 HydrophobicContact CB-CG2 4.19Å; Q244-T256 HydrophobicContact CG-CG2 4.22Å; F246-T256 HydrophobicContact CD1-CG2 4.26Å; F246-T256 HydrophobicContact CE1-CG2 4Å; F246-T256 WeakPolarHBondContact CE1-OG1 3.27Å; T256-K275 PolarHBondContact O-NZ 3.32Å
257L91.3Very high91Very high1 Ų152.5 Ų52.51%0.00530%0.299CS..EExtended strand (participates in β ladder)trans-117.4139.1176.5-60.2176.5000110.4Q244 I245 V247 I255 V259 V268 K271 I272 K275Q244-L257 CarbonylContact C-O 3.5Å; Q244-L257 VanDerWaalsContact CA-O 3.26Å; Q244-L257 WeakPolarHBondContact CA-O 3.28Å; I245-L257 HydrophobicContact CG1-CB 4.01Å; I245-L257 PolarHBondContact N-O 2.81Å; I245-L257 PolarHBondContact O-N 2.85Å; V247-L257 HydrophobicContact CG2-CD1 3.6Å; V247-L257 HydrophobicContact CG2-CG 4.25Å; I255-L257 HydrophobicContact CG2-CD2 4.1Å; I255-L257 HydrophobicContact CG2-CG 4.49Å; L257-V259 HydrophobicContact CB-CG1 4.07Å; L257-V268 HydrophobicContact CD1-CG1 3.91Å; L257-K271 HydrophobicContact CD2-CB 4.31Å; L257-I272 HydrophobicContact CD1-CD1 4.09Å; L257-I272 HydrophobicContact CD1-CG1 3.55Å; L257-I272 HydrophobicContact CD2-CG1 4.38Å; L257-K275 HydrophobicContact CD2-CD 3.91Å
258E88.5Confident90.9Very high32 Ų3252.5 Ų52.515%0.1530%0.299CS..EExtended strand (participates in β ladder)trans-90123.3167.8-64.5-76.4160.500108R240 G242 Q244 K271R240-E258 WeakPolarHBondContact CA-OE1 3.32Å; G242-E258 WeakPolarHBondContact CA-OE2 3.24Å; G242-E258 PolarHBondContact N-OE2 3.15Å; G242-E258 VanDerWaalsContact N-OE2 3.1Å; Q244-E258 VanDerWaalsContact CD-OE1 3.29Å; Q244-E258 WeakPolarHBondContact CG-OE1 3.44Å; Q244-E258 PolarHBondContact NE2-OE1 3.48Å; E258-K271 PolarHBondContact O-NZ 3.24Å
259V90.7Very high90.9Very high4 Ų449.1 Ų49.12%0.02428%0.284CS..EExtended strand (participates in β ladder)trans-140.7158.7-171.8-63.30000111.5M243 I245 L257 D263 V268 K271 L298M243-V259 WeakPolarHBondContact CB-O 3.37Å; M243-V259 HydrophobicContact CE-CG2 4.3Å; M243-V259 HydrophobicContact CG-CG2 4.17Å; M243-V259 WeakPolarHBondContact O-CG2 3.47Å; M243-V259 PolarHBondContact O-N 2.84Å; I245-V259 HydrophobicContact CB-CG2 4.32Å; I245-V259 HydrophobicContact CD1-CG1 3.9Å; I245-V259 HydrophobicContact CD1-CG2 4.03Å; I245-V259 HydrophobicContact CG1-CG1 4Å; I245-V259 HydrophobicContact CG1-CG2 3.82Å; I245-V259 HydrophobicContact CG2-CG2 3.74Å; L257-V259 HydrophobicContact CB-CG1 4.07Å; V259-D263 VanDerWaalsContact CA-OD2 3.26Å; V259-D263 WeakPolarHBondContact CA-OD2 3.49Å; V259-D263 WeakPolarHBondContact CB-OD2 3.44Å; V259-V268 HydrophobicContact CG1-CG2 4.28Å; V259-K271 HydrophobicContact CG1-CD 4.31Å; V259-L298 HydrophobicContact CB-CD1 3.59Å; V259-L298 HydrophobicContact CG1-CD1 4.11Å; V259-L298 HydrophobicContact CG2-CD1 3.49Å; V259-L298 VanDerWaalsContact CG2-CD1 3.49Å
260E88.5Confident91Very high36 Ų3650.5 Ų50.517%0.16829%0.292CS..  trans-105.6150.1167.2-65.7-175.1167.200110P189 S262 D263P189-E260 WeakPolarHBondContact CB-OE1 3.21Å; E260-S262 WeakPolarHBondContact CB-OG 3.29Å; E260-S262 PolarHBondContact O-N 3.25Å; E260-S262 VanDerWaalsContact O-N 3.1Å; E260-S262 PolarHBondContact OE2-OG 2.83Å; E260-D263 PolarHBondContact N-OD2 3.39Å; E260-D263 VanDerWaalsContact O-CB 3.27Å; E260-D263 WeakPolarHBondContact O-CB 3.37Å; E260-D263 PolarHBondContact O-N 3.28Å
261P91.4Very high91.5Very high66 Ų6646.5 Ų46.543%0.42927%0.269SS..THydrogen-bonded Turntrans-56-27.7175.3-24.332.7000114M243 D263 L298 S299M243-P261 HydrophobicContact SD-CG 3.81Å; P261-D263 VanDerWaalsContact C-N 3.34Å; P261-L298 PolarHBondContact O-N 2.87Å; P261-S299 WeakPolarHBondContact O-CB 3.36Å; P261-S299 PolarHBondContact O-N 3.11Å
262S90.6Very high92.1Very high72 Ų7240.4 Ų40.450%0.50323%0.232SC..THydrogen-bonded Turntrans-76.4-13.9175.637.50000114.2E260 T264 T297E260-S262 WeakPolarHBondContact CB-OG 3.29Å; E260-S262 PolarHBondContact O-N 3.25Å; E260-S262 VanDerWaalsContact O-N 3.1Å; E260-S262 PolarHBondContact OE2-OG 2.83Å; S262-T264 PolarHBondContact O-N 3.3Å; S262-T297 WeakPolarHBondContact O-CG2 3.47Å
263D91.9Very high92.4Very high17 Ų1740.2 Ų40.29%0.09122%0.217CC..  trans-59.9130.3179.3-80.7-24.8000110.1V259 E260 P261 N267 V268 K271 T297 L298V259-D263 VanDerWaalsContact CA-OD2 3.26Å; V259-D263 WeakPolarHBondContact CA-OD2 3.49Å; V259-D263 WeakPolarHBondContact CB-OD2 3.44Å; E260-D263 PolarHBondContact N-OD2 3.39Å; E260-D263 VanDerWaalsContact O-CB 3.27Å; E260-D263 WeakPolarHBondContact O-CB 3.37Å; E260-D263 PolarHBondContact O-N 3.28Å; P261-D263 VanDerWaalsContact C-N 3.34Å; D263-N267 HydrophobicContact CB-CB 4.45Å; D263-V268 HydrophobicContact CB-CG2 4.25Å; D263-K271 IonicContact OD1-NZ 3.49Å; D263-K271 IonicContact OD2-NZ 2.69Å; D263-K271 PolarHBondContact OD2-NZ 3.44Å; D263-T297 CarbonylContact O-C 3.59Å; D263-T297 WeakPolarHBondContact O-CA 3.42Å; D263-L298 HydrophobicContact CB-CD1 4.24Å; D263-L298 HydrophobicContact CB-CG 4.49Å; D263-L298 PolarHBondContact O-N 3.46Å
264T95.8Very high92.1Very high36 Ų3641.3 Ų41.322%0.22123%0.227CC..BIsolated β-bridgetrans-70.7156.7170.262.30000110.6S262 E266 N267 V268 R296S262-T264 PolarHBondContact O-N 3.3Å; T264-E266 PolarHBondContact O-N 3.45Å; T264-N267 WeakPolarHBondContact O-CB 3.32Å; T264-N267 PolarHBondContact O-N 2.81Å; T264-N267 VanDerWaalsContact O-N 3.1Å; T264-N267 PolarHBondContact OG1-N 3.24Å; T264-N267 PolarHBondContact OG1-OD1 2.84Å; T264-V268 WeakPolarHBondContact O-CG2 3.43Å; T264-V268 PolarHBondContact O-N 2.89Å; T264-R296 CarbonylContact C-O 3.56Å; T264-R296 WeakPolarHBondContact CA-O 3.3Å
265I97Very high91.9Very high0 Ų044 Ų440%023%0.234CC..Hα-helixtrans-61.6-32.5174.9-60.7-56.3000111V268 K269 L285 L292 E293 D294 R296 L298 Y301I265-V268 PolarHBondContact O-N 2.88Å; I265-K269 WeakPolarHBondContact O-CG 3.24Å; I265-K269 PolarHBondContact O-N 2.91Å; I265-L285 HydrophobicContact CG2-CD1 4.24Å; I265-L292 HydrophobicContact CB-CB 4.5Å; I265-L292 HydrophobicContact CD1-CB 3.9Å; I265-L292 HydrophobicContact CD1-CD1 3.64Å; I265-L292 HydrophobicContact CD1-CG 4.29Å; I265-L292 HydrophobicContact CG1-CB 3.89Å; I265-L292 HydrophobicContact CG2-CB 3.81Å; I265-E293 WeakPolarHBondContact CB-O 3.37Å; I265-E293 VanDerWaalsContact CG1-O 3.29Å; I265-E293 WeakPolarHBondContact CG1-O 3.23Å; I265-D294 PolarHBondContact N-O 3.1Å; I265-R296 WeakPolarHBondContact CG1-O 3.5Å; I265-R296 PolarHBondContact N-O 3.25Å; I265-L298 HydrophobicContact CD1-CD2 3.9Å; I265-Y301 HydrophobicContact CD1-CD2 4.42Å; I265-Y301 HydrophobicContact CG1-CE2 4.21Å
266E94.9Very high91.7Very high111 Ų11146.7 Ų46.752%0.51925%0.246SC..Hα-helixtrans-59.3-48.6170.3-169.2170.2-167.300112.1T264 V268 K269 T270 D294T264-E266 PolarHBondContact O-N 3.45Å; E266-V268 VanDerWaalsContact C-N 3.27Å; E266-V268 PolarHBondContact O-N 3.38Å; E266-K269 WeakPolarHBondContact O-CB 3.39Å; E266-K269 PolarHBondContact O-N 3.11Å; E266-T270 PolarHBondContact O-N 2.82Å; E266-T270 PolarHBondContact O-OG1 3.02Å; E266-D294 HydrophobicContact CB-CB 4.26Å; E266-D294 PolarHBondContact N-O 2.87Å; E266-D294 VanDerWaalsContact N-O 3.08Å
267N92.3Very high91.4Very high74 Ų7447 Ų4740%0.39626%0.26SS..Hα-helixtrans-58.7-40.4176-67.2-3000111.8D263 T264 K269 T270 K271D263-N267 HydrophobicContact CB-CB 4.45Å; T264-N267 WeakPolarHBondContact O-CB 3.32Å; T264-N267 PolarHBondContact O-N 2.81Å; T264-N267 VanDerWaalsContact O-N 3.1Å; T264-N267 PolarHBondContact OG1-N 3.24Å; T264-N267 PolarHBondContact OG1-OD1 2.84Å; N267-K269 VanDerWaalsContact C-N 3.31Å; N267-K269 PolarHBondContact O-N 2.7Å; N267-T270 PolarHBondContact O-N 3.02Å; N267-K271 WeakPolarHBondContact O-CG 3.43Å; N267-K271 PolarHBondContact O-N 2.6Å
268V95.5Very high91Very high0 Ų048.2 Ų48.20%027%0.266CS..Hα-helixtrans-63.3-39.3177177.20000110.9I245 L257 V259 D263 T264 I265 E266 K271 I272 L285 L298I245-V268 HydrophobicContact CD1-CG1 4.26Å; L257-V268 HydrophobicContact CD1-CG1 3.91Å; V259-V268 HydrophobicContact CG1-CG2 4.28Å; D263-V268 HydrophobicContact CB-CG2 4.25Å; T264-V268 WeakPolarHBondContact O-CG2 3.43Å; T264-V268 PolarHBondContact O-N 2.89Å; I265-V268 PolarHBondContact O-N 2.88Å; E266-V268 VanDerWaalsContact C-N 3.27Å; E266-V268 PolarHBondContact O-N 3.38Å; V268-K271 PolarHBondContact O-N 2.81Å; V268-I272 HydrophobicContact CG1-CD1 4.36Å; V268-I272 WeakPolarHBondContact O-CG1 3.19Å; V268-I272 PolarHBondContact O-N 2.79Å; V268-I272 VanDerWaalsContact O-N 3.07Å; V268-L285 HydrophobicContact CB-CD1 4.4Å; V268-L285 HydrophobicContact CG1-CD1 3.82Å; V268-L298 HydrophobicContact CG2-CD1 4.07Å; V268-L298 HydrophobicContact CG2-CD2 4.01Å; V268-L298 HydrophobicContact CG2-CG 4.1Å
269K95Very high90.9Very high15 Ų1547.4 Ų47.47%0.06526%0.263CS..Hα-helixtrans-65.9-41175.8-71.2172.2164.6-168.90112.3I265 E266 N267 K271 I272 Q273 P280 Q283 L285 D294I265-K269 WeakPolarHBondContact O-CG 3.24Å; I265-K269 PolarHBondContact O-N 2.91Å; E266-K269 WeakPolarHBondContact O-CB 3.39Å; E266-K269 PolarHBondContact O-N 3.11Å; N267-K269 VanDerWaalsContact C-N 3.31Å; N267-K269 PolarHBondContact O-N 2.7Å; K269-K271 VanDerWaalsContact C-N 3.32Å; K269-K271 PolarHBondContact O-N 2.8Å; K269-I272 WeakPolarHBondContact O-CB 3.45Å; K269-I272 PolarHBondContact O-N 3.4Å; K269-I272 VanDerWaalsContact O-N 3.1Å; K269-Q273 PolarHBondContact O-N 3.17Å; K269-P280 HydrophobicContact CB-CB 3.8Å; K269-P280 HydrophobicContact CB-CG 4.31Å; K269-P280 HydrophobicContact CD-CB 4.22Å; K269-P280 PolarHBondContact NZ-O 2.9Å; K269-Q283 HydrophobicContact CD-CB 4.33Å; K269-Q283 WeakPolarHBondContact CE-O 3.45Å; K269-Q283 HydrophobicContact CG-CB 4.07Å; K269-Q283 PolarHBondContact NZ-O 2.9Å; K269-Q283 VanDerWaalsContact NZ-O 3.17Å; K269-Q283 PolarHBondContact O-NE2 3.31Å; K269-Q283 PolarHBondContact O-OE1 3.35Å; K269-L285 HydrophobicContact CG-CD1 4.01Å; K269-D294 WeakPolarHBondContact CE-OD1 3.4Å; K269-D294 VanDerWaalsContact NZ-CG 3.32Å; K269-D294 IonicContact NZ-OD1 3.49Å; K269-D294 PolarHBondContact NZ-OD1 2.93Å; K269-D294 IonicContact NZ-OD2 3.23Å; K269-D294 PolarHBondContact NZ-OD2 3.23Å; K269-D294 VanDerWaalsContact NZ-OD2 3.17Å
270T91.7Very high90.8Very high53 Ų5348.3 Ų48.333%0.32527%0.269SS..Hα-helixtrans-59.3-44.2172.7-53.50000110.8E266 N267 I272 Q273 D274E266-T270 PolarHBondContact O-N 2.82Å; E266-T270 PolarHBondContact O-OG1 3.02Å; N267-T270 PolarHBondContact O-N 3.02Å; T270-I272 PolarHBondContact O-N 3.19Å; T270-Q273 WeakPolarHBondContact O-CA 3.42Å; T270-Q273 VanDerWaalsContact O-CB 3.31Å; T270-Q273 WeakPolarHBondContact O-CB 3.3Å; T270-Q273 PolarHBondContact O-N 3.34Å; T270-D274 VanDerWaalsContact O-CG 3.31Å; T270-D274 PolarHBondContact O-N 2.94Å
271K92.9Very high90.5Very high54 Ų5449.1 Ų49.124%0.23528%0.275CS..Hα-helixtrans-60.3-30.9174.8-70.6176.6177.5-173.30113.3L257 E258 V259 D263 N267 V268 K269 K275L257-K271 HydrophobicContact CD2-CB 4.31Å; E258-K271 PolarHBondContact O-NZ 3.24Å; V259-K271 HydrophobicContact CG1-CD 4.31Å; D263-K271 IonicContact OD1-NZ 3.49Å; D263-K271 IonicContact OD2-NZ 2.69Å; D263-K271 PolarHBondContact OD2-NZ 3.44Å; N267-K271 WeakPolarHBondContact O-CG 3.43Å; N267-K271 PolarHBondContact O-N 2.6Å; V268-K271 PolarHBondContact O-N 2.81Å; K269-K271 VanDerWaalsContact C-N 3.32Å; K269-K271 PolarHBondContact O-N 2.8Å; K271-K275 PolarHBondContact O-N 3.31Å
272I93.5Very high90.3Very high0 Ų047.7 Ų47.70%026%0.262CS..Hα-helixtrans-73.4-41.4172.9-66.2163.8000110.6V247 L257 V268 K269 T270 D274 K275 E276 Q283 L285 L311V247-I272 HydrophobicContact CG1-CD1 4.2Å; V247-I272 HydrophobicContact CG2-CD1 4.2Å; L257-I272 HydrophobicContact CD1-CD1 4.09Å; L257-I272 HydrophobicContact CD1-CG1 3.55Å; L257-I272 HydrophobicContact CD2-CG1 4.38Å; V268-I272 HydrophobicContact CG1-CD1 4.36Å; V268-I272 WeakPolarHBondContact O-CG1 3.19Å; V268-I272 PolarHBondContact O-N 2.79Å; V268-I272 VanDerWaalsContact O-N 3.07Å; K269-I272 WeakPolarHBondContact O-CB 3.45Å; K269-I272 PolarHBondContact O-N 3.4Å; K269-I272 VanDerWaalsContact O-N 3.1Å; T270-I272 PolarHBondContact O-N 3.19Å; I272-D274 VanDerWaalsContact C-N 3.32Å; I272-D274 PolarHBondContact O-N 3.02Å; I272-K275 PolarHBondContact O-N 2.9Å; I272-E276 WeakPolarHBondContact O-CB 3.3Å; I272-E276 PolarHBondContact O-N 3.48Å; I272-Q283 VanDerWaalsContact CD1-OE1 3.29Å; I272-L285 HydrophobicContact CD1-CD1 4.07Å; I272-L285 HydrophobicContact CD1-CD2 3.75Å; I272-L285 HydrophobicContact CD1-CG 4.39Å; I272-L311 HydrophobicContact CG2-CD2 4.12Å
273Q90.5Very high90.3Very high50 Ų5044.4 Ų44.423%0.23424%0.239CC..Hα-helixtrans-57.8-46.6174.9-177-179.821.800110.7K269 T270 K275 E276 G277 I278 P280 E336K269-Q273 PolarHBondContact O-N 3.17Å; T270-Q273 WeakPolarHBondContact O-CA 3.42Å; T270-Q273 VanDerWaalsContact O-CB 3.31Å; T270-Q273 WeakPolarHBondContact O-CB 3.3Å; T270-Q273 PolarHBondContact O-N 3.34Å; Q273-K275 VanDerWaalsContact C-N 3.26Å; Q273-K275 PolarHBondContact O-N 2.73Å; Q273-E276 PolarHBondContact O-N 3.45Å; Q273-G277 WeakPolarHBondContact O-CA 3.41Å; Q273-G277 PolarHBondContact O-N 3.26Å; Q273-I278 VanDerWaalsContact CA-O 3.23Å; Q273-I278 WeakPolarHBondContact CA-O 3.27Å; Q273-I278 WeakPolarHBondContact CB-O 3.49Å; Q273-P280 HydrophobicContact CB-CG 4.48Å; Q273-P280 VanDerWaalsContact CD-CD 3.48Å; Q273-P280 VanDerWaalsContact OE1-CD 3.23Å; Q273-E336 PolarHBondContact NE2-OE1 3.43Å; Q273-E336 VanDerWaalsContact NE2-OE1 3.14Å
274D85.2Confident90.4Very high124 Ų12448 Ų4866%0.66325%0.251SS*.Hα-helixtrans-62.1-34179.9-64.3-25.7000112.6T270 I272T270-D274 VanDerWaalsContact O-CG 3.31Å; T270-D274 PolarHBondContact O-N 2.94Å; I272-D274 VanDerWaalsContact C-N 3.32Å; I272-D274 PolarHBondContact O-N 3.02Å
275K87.1Confident90.4Very high121 Ų12146.3 Ų46.353%0.52624%0.241SC..Hα-helixtrans-86.4-35.9-179.2-77.7-157.2178.9-165.50114.6I255 T256 L257 K271 I272 Q273I255-K275 HydrophobicContact CG2-CD 4.22Å; T256-K275 PolarHBondContact O-NZ 3.32Å; L257-K275 HydrophobicContact CD2-CD 3.91Å; K271-K275 PolarHBondContact O-N 3.31Å; I272-K275 PolarHBondContact O-N 2.9Å; Q273-K275 VanDerWaalsContact C-N 3.26Å; Q273-K275 PolarHBondContact O-N 2.73Å
276E89.2Confident90.4Very high63 Ų6348.6 Ų48.629%0.29425%0.253SS..Hα-helixtrans-121.9-4-167.1-63.5-74.1142.700112.9K253 I255 I272 Q273 I278K253-E276 WeakPolarHBondContact CE-OE1 3.11Å; K253-E276 IonicContact NZ-OE1 2.99Å; K253-E276 PolarHBondContact NZ-OE1 2.81Å; K253-E276 IonicContact NZ-OE2 2.73Å; K253-E276 PolarHBondContact NZ-OE2 2.92Å; I255-E276 HydrophobicContact CD1-CG 3.62Å; I255-E276 HydrophobicContact CG1-CG 4.03Å; I255-E276 HydrophobicContact CG2-CG 4.43Å; I272-E276 WeakPolarHBondContact O-CB 3.3Å; I272-E276 PolarHBondContact O-N 3.48Å; Q273-E276 PolarHBondContact O-N 3.45Å; E276-I278 HydrophobicContact CB-CD1 3.89Å; E276-I278 HydrophobicContact CB-CG1 3.91Å; E276-I278 PolarHBondContact O-N 2.8Å
277G84.8Confident90.5Very high59 Ų5945.2 Ų45.261%0.60824%0.236SC*.  trans70.915.6-178.800000114.3Q273 P279Q273-G277 WeakPolarHBondContact O-CA 3.41Å; Q273-G277 PolarHBondContact O-N 3.26Å; G277-P279 WeakPolarHBondContact O-CD 3.44Å
278I84.7Confident90.5Very high26 Ų2645.8 Ų45.813%0.13325%0.252CS..  trans-93.7117.4-174.6-54.1176.2000109.5Q273 E276 Q282 Q283 L311 L313Q273-I278 VanDerWaalsContact CA-O 3.23Å; Q273-I278 WeakPolarHBondContact CA-O 3.27Å; Q273-I278 WeakPolarHBondContact CB-O 3.49Å; E276-I278 HydrophobicContact CB-CD1 3.89Å; E276-I278 HydrophobicContact CB-CG1 3.91Å; E276-I278 PolarHBondContact O-N 2.8Å; I278-Q282 HydrophobicContact CG2-CB 4.37Å; I278-Q283 HydrophobicContact CB-CG 4.42Å; I278-Q283 HydrophobicContact CG2-CG 3.73Å; I278-Q283 PolarHBondContact O-NE2 2.7Å; I278-L311 HydrophobicContact CD1-CD2 4.19Å; I278-L313 HydrophobicContact CD1-CD1 4.39Å; I278-L313 HydrophobicContact CD1-CD2 4.02Å; I278-L313 HydrophobicContact CG2-CD2 3.61Å
279P84.6Confident90.3Very high15 Ų1549.4 Ų49.410%0.09729%0.289CS..  trans-59.1139.8179-29.939.4000114.2G277 D281 Q282 Q283G277-P279 WeakPolarHBondContact O-CD 3.44Å; P279-D281 VanDerWaalsContact C-N 3.26Å; P279-D281 WeakPolarHBondContact CB-OD1 3.39Å; P279-D281 PolarHBondContact O-N 2.77Å; P279-Q282 HydrophobicContact CB-CG 4.35Å; P279-Q282 WeakPolarHBondContact O-CB 3.42Å; P279-Q282 PolarHBondContact O-N 2.87Å; P279-Q283 WeakPolarHBondContact O-CG 3.16Å; P279-Q283 PolarHBondContact O-N 3.33Å
280P88.7Confident90.3Very high23 Ų2355.6 Ų55.615%0.14932%0.316CS..G310 helixtrans-56.1-31.5-176.9-30.937.6000115.7K269 Q273 Q282 Q283 E336K269-P280 HydrophobicContact CB-CB 3.8Å; K269-P280 HydrophobicContact CB-CG 4.31Å; K269-P280 HydrophobicContact CD-CB 4.22Å; K269-P280 PolarHBondContact NZ-O 2.9Å; Q273-P280 HydrophobicContact CB-CG 4.48Å; Q273-P280 VanDerWaalsContact CD-CD 3.48Å; Q273-P280 VanDerWaalsContact OE1-CD 3.23Å; P280-Q282 VanDerWaalsContact C-N 3.31Å; P280-Q283 WeakPolarHBondContact O-CB 3.38Å; P280-Q283 PolarHBondContact O-N 2.84Å; P280-Q283 VanDerWaalsContact O-N 3.16Å; P280-E336 WeakPolarHBondContact CD-OE1 3.43Å
281D84.1Confident90.4Very high53 Ų5357.2 Ų57.228%0.28332%0.319SS..G310 helixtrans-71.3-25178.164-17.7000113.2P279 Q283 G318P279-D281 VanDerWaalsContact C-N 3.26Å; P279-D281 WeakPolarHBondContact CB-OD1 3.39Å; P279-D281 PolarHBondContact O-N 2.77Å; D281-Q283 VanDerWaalsContact C-N 3.34Å; D281-G318 WeakPolarHBondContact OD2-CA 3.07Å
282Q86.1Confident90.6Very high36 Ų3654.8 Ų54.817%0.16831%0.309CS..G310 helixtrans-83-13.9171.3-62.3-176.97.600112.4I278 P279 P280 L313 R314 E334I278-Q282 HydrophobicContact CG2-CB 4.37Å; P279-Q282 HydrophobicContact CB-CG 4.35Å; P279-Q282 WeakPolarHBondContact O-CB 3.42Å; P279-Q282 PolarHBondContact O-N 2.87Å; P280-Q282 VanDerWaalsContact C-N 3.31Å; Q282-L313 CarbonylContact O-C 3.48Å; Q282-L313 WeakPolarHBondContact O-CA 3.48Å; Q282-R314 PolarHBondContact O-N 2.98Å; Q282-E334 VanDerWaalsContact NE2-CB 3.34Å
283Q91.4Very high90.7Very high2 Ų259.8 Ų59.81%0.00933%0.333CS..EExtended strand (participates in β ladder)trans-89.8129.2-177.1-61.817835.400112.1K269 I272 I278 P279 P280 D281 L311K269-Q283 HydrophobicContact CD-CB 4.33Å; K269-Q283 WeakPolarHBondContact CE-O 3.45Å; K269-Q283 HydrophobicContact CG-CB 4.07Å; K269-Q283 PolarHBondContact NZ-O 2.9Å; K269-Q283 VanDerWaalsContact NZ-O 3.17Å; K269-Q283 PolarHBondContact O-NE2 3.31Å; K269-Q283 PolarHBondContact O-OE1 3.35Å; I272-Q283 VanDerWaalsContact CD1-OE1 3.29Å; I278-Q283 HydrophobicContact CB-CG 4.42Å; I278-Q283 HydrophobicContact CG2-CG 3.73Å; I278-Q283 PolarHBondContact O-NE2 2.7Å; P279-Q283 WeakPolarHBondContact O-CG 3.16Å; P279-Q283 PolarHBondContact O-N 3.33Å; P280-Q283 WeakPolarHBondContact O-CB 3.38Å; P280-Q283 PolarHBondContact O-N 2.84Å; P280-Q283 VanDerWaalsContact O-N 3.16Å; D281-Q283 VanDerWaalsContact C-N 3.34Å; Q283-L311 HydrophobicContact CB-CD1 3.78Å; Q283-L311 HydrophobicContact CG-CD1 3.99Å
284R92.8Very high90.7Very high93 Ų9360.8 Ų60.835%0.35134%0.339SS..EExtended strand (participates in β ladder)trans-122.1109.7168.1-159.4-178.7-157.8-176.81.6109.2Q291 V312R284-Q291 HydrophobicContact CG-CG 4.07Å; R284-V312 HydrophobicContact CB-CB 4.3Å; R284-V312 VanDerWaalsContact CB-O 3.27Å; R284-V312 WeakPolarHBondContact CB-O 3.1Å; R284-V312 PolarHBondContact N-O 3.29Å; R284-V312 PolarHBondContact O-N 3.29Å
285L96Very high91.1Very high1 Ų158.2 Ų58.21%0.00534%0.343CS..EExtended strand (participates in β ladder)trans-91.2135178.4-65.4175.6000110.7V247 I265 V268 K269 I272 L292 L309 L311V247-L285 HydrophobicContact CG1-CD2 4.09Å; I265-L285 HydrophobicContact CG2-CD1 4.24Å; V268-L285 HydrophobicContact CB-CD1 4.4Å; V268-L285 HydrophobicContact CG1-CD1 3.82Å; K269-L285 HydrophobicContact CG-CD1 4.01Å; I272-L285 HydrophobicContact CD1-CD1 4.07Å; I272-L285 HydrophobicContact CD1-CD2 3.75Å; I272-L285 HydrophobicContact CD1-CG 4.39Å; L285-L292 HydrophobicContact CB-CB 4.24Å; L285-L292 HydrophobicContact CB-CD1 3.93Å; L285-L292 HydrophobicContact CB-CG 4.28Å; L285-L292 PolarHBondContact O-N 2.99Å; L285-L309 HydrophobicContact CB-CD2 4.48Å; L285-L309 HydrophobicContact CD1-CD2 4.35Å; L285-L311 HydrophobicContact CD2-CB 4.24Å; L285-L311 HydrophobicContact CD2-CD1 3.92Å
286I96.5Very high91.5Very high47 Ų4757.9 Ų57.924%0.24134%0.338CS..EExtended strand (participates in β ladder)trans-127.5131.6-179.6-56.7174.1000108.6K290 L309 H310 V312I286-K290 CarbonylContact C-O 3.58Å; I286-K290 VanDerWaalsContact CA-O 3.31Å; I286-K290 WeakPolarHBondContact CA-O 3.42Å; I286-K290 WeakPolarHBondContact CG2-O 3.42Å; I286-L309 CarbonylContact O-C 3.57Å; I286-L309 WeakPolarHBondContact O-CA 3.26Å; I286-H310 HydrophobicContact CB-CB 4.34Å; I286-H310 PolarHBondContact N-O 3.22Å; I286-H310 PolarHBondContact O-N 2.9Å; I286-V312 HydrophobicContact CD1-CG2 3.73Å
287F97.1Very high91.8Very high40 Ų4056.2 Ų56.218%0.17533%0.332CS..EExtended strand (participates in β ladder)trans-135.3134.8173.3-177.1-112.4000109.8G289 K290 L292 I303 L309F287-G289 PolarHBondContact O-N 3.4Å; F287-G289 VanDerWaalsContact O-N 3.1Å; F287-K290 PolarHBondContact N-O 2.86Å; F287-K290 PolarHBondContact O-N 2.74Å; F287-L292 HydrophobicContact CB-CD1 4.13Å; F287-L292 HydrophobicContact CB-CD2 3.9Å; F287-L292 HydrophobicContact CB-CG 4.29Å; F287-I303 HydrophobicContact CB-CD1 4.32Å; F287-I303 HydrophobicContact CD1-CD1 4.13Å; F287-I303 HydrophobicContact CD1-CG1 3.53Å; F287-I303 HydrophobicContact CD2-CG1 4.35Å; F287-I303 HydrophobicContact CE1-CG1 3.64Å; F287-I303 HydrophobicContact CE2-CG1 4.46Å; F287-I303 HydrophobicContact CG-CD1 4.16Å; F287-I303 HydrophobicContact CG-CG1 3.9Å; F287-I303 HydrophobicContact CZ-CG1 4.12Å; F287-L309 HydrophobicContact CB-CG 4.26Å; F287-L309 HydrophobicContact CD2-CD1 4.04Å; F287-L309 HydrophobicContact CD2-CG 4.29Å
288A93.4Very high92.3Very high87 Ų8753.4 Ų53.472%0.71930%0.303SS*.THydrogen-bonded Turntrans47.540.8-178.700000113.8K290A288-K290 PolarHBondContact O-N 2.75Å
289G91Very high92.7Very high76 Ų7655.2 Ų55.278%0.78432%0.318SS*.THydrogen-bonded Turntrans74.6-1.7-17900000115.6F287F287-G289 PolarHBondContact O-N 3.4Å; F287-G289 VanDerWaalsContact O-N 3.1Å
290K94.2Very high93.2Very high144 Ų14459.1 Ų59.163%0.62634%0.338SS*.EExtended strand (participates in β ladder)trans-102.4137.7177.4-66.3-177.2180178.30110.9I286 F287 A288I286-K290 CarbonylContact C-O 3.58Å; I286-K290 VanDerWaalsContact CA-O 3.31Å; I286-K290 WeakPolarHBondContact CA-O 3.42Å; I286-K290 WeakPolarHBondContact CG2-O 3.42Å; F287-K290 PolarHBondContact N-O 2.86Å; F287-K290 PolarHBondContact O-N 2.74Å; A288-K290 PolarHBondContact O-N 2.75Å
291Q94.9Very high93.6Very high87 Ų8759.9 Ų59.941%0.40734%0.339SS..EExtended strand (participates in β ladder)trans-71.4136.1167.5-179.5-177.5-20.100109.5R284R284-Q291 HydrophobicContact CG-CG 4.07Å
292L96.4Very high94.1Very high4 Ų462.8 Ų62.82%0.02135%0.354CS..PPolyproline II helixtrans-84.8136.1177.3-55.2-173.7000110.7I265 L285 F287 Y301 I303 L309I265-L292 HydrophobicContact CB-CB 4.5Å; I265-L292 HydrophobicContact CD1-CB 3.9Å; I265-L292 HydrophobicContact CD1-CD1 3.64Å; I265-L292 HydrophobicContact CD1-CG 4.29Å; I265-L292 HydrophobicContact CG1-CB 3.89Å; I265-L292 HydrophobicContact CG2-CB 3.81Å; L285-L292 HydrophobicContact CB-CB 4.24Å; L285-L292 HydrophobicContact CB-CD1 3.93Å; L285-L292 HydrophobicContact CB-CG 4.28Å; L285-L292 PolarHBondContact O-N 2.99Å; F287-L292 HydrophobicContact CB-CD1 4.13Å; F287-L292 HydrophobicContact CB-CD2 3.9Å; F287-L292 HydrophobicContact CB-CG 4.29Å; L292-Y301 HydrophobicContact CB-CE2 4.27Å; L292-Y301 HydrophobicContact CD2-CD1 3.61Å; L292-Y301 HydrophobicContact CD2-CD2 3.67Å; L292-Y301 HydrophobicContact CD2-CE1 3.74Å; L292-Y301 HydrophobicContact CD2-CE2 3.76Å; L292-Y301 HydrophobicContact CD2-CG 3.57Å; L292-I303 HydrophobicContact CD1-CD1 3.87Å; L292-I303 HydrophobicContact CD2-CD1 4.44Å; L292-L309 HydrophobicContact CD1-CD2 3.53Å; L292-L309 HydrophobicContact CD1-CG 4.19Å
293E95.2Very high94.5Very high105 Ų10561.4 Ų61.449%0.49135%0.348SS..PPolyproline II helixtrans-95.6133.3-179.9-67.9171.1-174.900110.7I265 G295 R296 Y301I265-E293 WeakPolarHBondContact CB-O 3.37Å; I265-E293 VanDerWaalsContact CG1-O 3.29Å; I265-E293 WeakPolarHBondContact CG1-O 3.23Å; E293-G295 VanDerWaalsContact C-N 3.32Å; E293-G295 PolarHBondContact O-N 2.92Å; E293-R296 HydrophobicContact CB-CG 4.27Å; E293-R296 PolarHBondContact O-N 2.79Å; E293-R296 VanDerWaalsContact O-N 3.1Å; E293-R296 IonicContact OE2-CZ 2.61Å; E293-R296 IonicContact OE2-NE 2.6Å; E293-R296 PolarHBondContact OE2-NE 2.88Å; E293-R296 IonicContact OE2-NH2 2.74Å; E293-R296 PolarHBondContact OE2-NH2 2.81Å; E293-Y301 WeakPolarHBondContact CB-OH 3.39Å; E293-Y301 PolarHBondContact N-OH 3.37Å
294D92.4Very high94.5Very high70 Ų7067 Ų6737%0.37437%0.374SS..THydrogen-bonded Turntrans-56-39.5-169.2-69-14.5000114I265 E266 K269 R296I265-D294 PolarHBondContact N-O 3.1Å; E266-D294 HydrophobicContact CB-CB 4.26Å; E266-D294 PolarHBondContact N-O 2.87Å; E266-D294 VanDerWaalsContact N-O 3.08Å; K269-D294 WeakPolarHBondContact CE-OD1 3.4Å; K269-D294 VanDerWaalsContact NZ-CG 3.32Å; K269-D294 IonicContact NZ-OD1 3.49Å; K269-D294 PolarHBondContact NZ-OD1 2.93Å; K269-D294 IonicContact NZ-OD2 3.23Å; K269-D294 PolarHBondContact NZ-OD2 3.23Å; K269-D294 VanDerWaalsContact NZ-OD2 3.17Å; D294-R296 VanDerWaalsContact C-N 3.34Å; D294-R296 PolarHBondContact O-N 2.89Å
295G92.2Very high94.5Very high71 Ų7168.8 Ų68.873%0.73238%0.384SS*.THydrogen-bonded Turntrans-82.2-0.6-17800000116.1E293E293-G295 VanDerWaalsContact C-N 3.32Å; E293-G295 PolarHBondContact O-N 2.92Å
296R95.8Very high94.3Very high113 Ų11374.8 Ų74.843%0.42641%0.412SS..SBendtrans-95.6159176.1-67.6-165-166.6-140.8-0.5111.2T264 I265 E293 D294 D300 Y301T264-R296 CarbonylContact C-O 3.56Å; T264-R296 WeakPolarHBondContact CA-O 3.3Å; I265-R296 WeakPolarHBondContact CG1-O 3.5Å; I265-R296 PolarHBondContact N-O 3.25Å; E293-R296 HydrophobicContact CB-CG 4.27Å; E293-R296 PolarHBondContact O-N 2.79Å; E293-R296 VanDerWaalsContact O-N 3.1Å; E293-R296 IonicContact OE2-CZ 2.61Å; E293-R296 IonicContact OE2-NE 2.6Å; E293-R296 PolarHBondContact OE2-NE 2.88Å; E293-R296 IonicContact OE2-NH2 2.74Å; E293-R296 PolarHBondContact OE2-NH2 2.81Å; D294-R296 VanDerWaalsContact C-N 3.34Å; D294-R296 PolarHBondContact O-N 2.89Å; R296-D300 HydrophobicContact CB-CB 4.25Å; R296-Y301 HydrophobicContact CB-CD2 4.33Å; R296-Y301 HydrophobicContact CB-CE2 3.65Å; R296-Y301 HydrophobicContact CG-CE2 4.29Å
297T95.6Very high94.3Very high28 Ų2873.5 Ų73.517%0.17241%0.407CS..BIsolated β-bridgetrans-89.8164.7176.667.80000112.4S262 D263 S299 D300S262-T297 WeakPolarHBondContact O-CG2 3.47Å; D263-T297 CarbonylContact O-C 3.59Å; D263-T297 WeakPolarHBondContact O-CA 3.42Å; T297-S299 PolarHBondContact O-N 3.5Å; T297-S299 PolarHBondContact OG1-N 2.85Å; T297-S299 PolarHBondContact OG1-OG 3.24Å; T297-D300 PolarHBondContact N-OD2 2.97Å; T297-D300 PolarHBondContact O-N 2.73Å; T297-D300 PolarHBondContact OG1-N 2.86Å; T297-D300 PolarHBondContact OG1-OD2 2.61Å
298L94.9Very high94.3Very high0 Ų073.9 Ų73.90%041%0.413CS..THydrogen-bonded Turntrans-58.2-37.9169.5-70.1-179.1000111.9I245 V259 P261 D263 I265 V268 D300 Y301 N302 I303I245-L298 HydrophobicContact CD1-CD1 4.29Å; I245-L298 HydrophobicContact CD1-CD2 4.36Å; V259-L298 HydrophobicContact CB-CD1 3.59Å; V259-L298 HydrophobicContact CG1-CD1 4.11Å; V259-L298 HydrophobicContact CG2-CD1 3.49Å; V259-L298 VanDerWaalsContact CG2-CD1 3.49Å; P261-L298 PolarHBondContact O-N 2.87Å; D263-L298 HydrophobicContact CB-CD1 4.24Å; D263-L298 HydrophobicContact CB-CG 4.49Å; D263-L298 PolarHBondContact O-N 3.46Å; I265-L298 HydrophobicContact CD1-CD2 3.9Å; V268-L298 HydrophobicContact CG2-CD1 4.07Å; V268-L298 HydrophobicContact CG2-CD2 4.01Å; V268-L298 HydrophobicContact CG2-CG 4.1Å; L298-D300 VanDerWaalsContact C-N 3.35Å; L298-D300 PolarHBondContact O-N 3.1Å; L298-Y301 PolarHBondContact O-N 2.88Å; L298-N302 PolarHBondContact O-N 3.47Å; L298-I303 HydrophobicContact CB-CB 4.25Å; L298-I303 HydrophobicContact CD2-CB 4.22Å; L298-I303 HydrophobicContact CD2-CD1 3.54Å; L298-I303 HydrophobicContact CD2-CG1 4.47Å; L298-I303 HydrophobicContact CD2-CG2 4.12Å; L298-I303 WeakPolarHBondContact O-CB 3.27Å; L298-I303 PolarHBondContact O-N 2.75Å
299S94.1Very high94.5Very high65 Ų6569.8 Ų69.846%0.45538%0.379SS..G310 helixtrans-64.5-35.2178.2750000113.2P261 T297 Y301 N302P261-S299 WeakPolarHBondContact O-CB 3.36Å; P261-S299 PolarHBondContact O-N 3.11Å; T297-S299 PolarHBondContact O-N 3.5Å; T297-S299 PolarHBondContact OG1-N 2.85Å; T297-S299 PolarHBondContact OG1-OG 3.24Å; S299-Y301 PolarHBondContact O-N 3.29Å; S299-N302 WeakPolarHBondContact O-CA 3.39Å; S299-N302 PolarHBondContact O-N 3.37Å
300D95.1Very high94.7Very high97 Ų9770.7 Ų70.752%0.51936%0.363SS..G310 helixtrans-61.9-27.7177.6-66.1-42.7000112.6R296 T297 L298R296-D300 HydrophobicContact CB-CB 4.25Å; T297-D300 PolarHBondContact N-OD2 2.97Å; T297-D300 PolarHBondContact O-N 2.73Å; T297-D300 PolarHBondContact OG1-N 2.86Å; T297-D300 PolarHBondContact OG1-OD2 2.61Å; L298-D300 VanDerWaalsContact C-N 3.35Å; L298-D300 PolarHBondContact O-N 3.1Å
301Y95.6Very high94.8Very high39 Ų3964 Ų6415%0.15333%0.334CS..G310 helixtrans-96.84.4175.7-70.8-76000113.5I265 L292 E293 R296 L298 S299 I303I265-Y301 HydrophobicContact CD1-CD2 4.42Å; I265-Y301 HydrophobicContact CG1-CE2 4.21Å; L292-Y301 HydrophobicContact CB-CE2 4.27Å; L292-Y301 HydrophobicContact CD2-CD1 3.61Å; L292-Y301 HydrophobicContact CD2-CD2 3.67Å; L292-Y301 HydrophobicContact CD2-CE1 3.74Å; L292-Y301 HydrophobicContact CD2-CE2 3.76Å; L292-Y301 HydrophobicContact CD2-CG 3.57Å; E293-Y301 WeakPolarHBondContact CB-OH 3.39Å; E293-Y301 PolarHBondContact N-OH 3.37Å; R296-Y301 HydrophobicContact CB-CD2 4.33Å; R296-Y301 HydrophobicContact CB-CE2 3.65Å; R296-Y301 HydrophobicContact CG-CE2 4.29Å; L298-Y301 PolarHBondContact O-N 2.88Å; S299-Y301 PolarHBondContact O-N 3.29Å; Y301-I303 PolarHBondContact O-N 3.14Å
302N95.1Very high94.5Very high114 Ų11461.7 Ų61.761%0.6133%0.326SS*.THydrogen-bonded Turntrans53.439-175.3-161.927.7000112.2L298 S299 Q304L298-N302 PolarHBondContact O-N 3.47Å; S299-N302 WeakPolarHBondContact O-CA 3.39Å; S299-N302 PolarHBondContact O-N 3.37Å; N302-Q304 PolarHBondContact O-N 3.47Å
303I94Very high94.1Very high7 Ų765.6 Ų65.64%0.03635%0.346CS..  trans-75.7121.8174.8-66.6168.1000107.4M243 I245 F287 L292 L298 Y301 L309M243-I303 HydrophobicContact CE-CG2 4.25Å; M243-I303 WeakPolarHBondContact CE-O 3.5Å; I245-I303 HydrophobicContact CG2-CG2 3.91Å; F287-I303 HydrophobicContact CB-CD1 4.32Å; F287-I303 HydrophobicContact CD1-CD1 4.13Å; F287-I303 HydrophobicContact CD1-CG1 3.53Å; F287-I303 HydrophobicContact CD2-CG1 4.35Å; F287-I303 HydrophobicContact CE1-CG1 3.64Å; F287-I303 HydrophobicContact CE2-CG1 4.46Å; F287-I303 HydrophobicContact CG-CD1 4.16Å; F287-I303 HydrophobicContact CG-CG1 3.9Å; F287-I303 HydrophobicContact CZ-CG1 4.12Å; L292-I303 HydrophobicContact CD1-CD1 3.87Å; L292-I303 HydrophobicContact CD2-CD1 4.44Å; L298-I303 HydrophobicContact CB-CB 4.25Å; L298-I303 HydrophobicContact CD2-CB 4.22Å; L298-I303 HydrophobicContact CD2-CD1 3.54Å; L298-I303 HydrophobicContact CD2-CG1 4.47Å; L298-I303 HydrophobicContact CD2-CG2 4.12Å; L298-I303 WeakPolarHBondContact O-CB 3.27Å; L298-I303 PolarHBondContact O-N 2.75Å; Y301-I303 PolarHBondContact O-N 3.14Å; I303-L309 HydrophobicContact CD1-CD1 4.3Å; I303-L309 HydrophobicContact CD1-CD2 4.34Å; I303-L309 HydrophobicContact CG2-CD1 4.04Å
304Q92.3Very high93.3Very high118 Ų11866.1 Ų66.155%0.55134%0.343SS*.  trans-106.9169.9-176.9-62-170-10.300111.7N302 E306 S307N302-Q304 PolarHBondContact O-N 3.47Å; Q304-E306 PolarHBondContact O-N 2.91Å; Q304-S307 PolarHBondContact N-OG 3.1Å; Q304-S307 WeakPolarHBondContact O-CB 3.5Å; Q304-S307 PolarHBondContact O-N 2.92Å; Q304-S307 PolarHBondContact O-OG 2.89Å
305K92.2Very high92Very high131 Ų13170.4 Ų70.457%0.5737%0.366SS*.THydrogen-bonded Turntrans-51.1137.5172.2-172.6172.5179.4173.40110.3M243 S307M243-K305 HydrophobicContact CG-CB 4.08Å; K305-S307 PolarHBondContact O-N 2.94Å
306E93Very high90.6Very high127 Ų12777 Ų7759%0.59337%0.368SS*.THydrogen-bonded Turntrans65.310.8-176.4-65.2173.2-170.600115.6Q244 F246 Q304Q244-E306 PolarHBondContact O-N 3.38Å; F246-E306 HydrophobicContact CD2-CB 4.49Å; F246-E306 WeakPolarHBondContact CD2-O 3.49Å; F246-E306 HydrophobicContact CE2-CB 3.83Å; F246-E306 HydrophobicContact CE2-CG 3.9Å; F246-E306 HydrophobicContact CZ-CG 4.4Å; Q304-E306 PolarHBondContact O-N 2.91Å
307S96.2Very high88.9Confident20 Ų2073.6 Ų73.614%0.1437%0.368CS..  trans-60.3143.1171.6-68.30000111.6F246 Q304 K305F246-S307 PolarHBondContact N-O 3.15Å; Q304-S307 PolarHBondContact N-OG 3.1Å; Q304-S307 WeakPolarHBondContact O-CB 3.5Å; Q304-S307 PolarHBondContact O-N 2.92Å; Q304-S307 PolarHBondContact O-OG 2.89Å; K305-S307 PolarHBondContact O-N 2.94Å
308T96.5Very high87.8Confident49 Ų4972.5 Ų72.530%0.30136%0.363SS..EExtended strand (participates in β ladder)trans-106.8114.7176.3-57.80000111.2F246 K248F246-T308 HydrophobicContact CB-CG2 4.43Å; F246-T308 CarbonylContact O-C 3.6Å; F246-T308 WeakPolarHBondContact O-CA 3.19Å; K248-T308 HydrophobicContact CB-CG2 4.28Å; K248-T308 HydrophobicContact CD-CG2 3.84Å; K248-T308 HydrophobicContact CG-CG2 3.81Å
309L97.1Very high87.5Confident0 Ų073.9 Ų73.90%037%0.369CS..EExtended strand (participates in β ladder)trans-90.9153.1169.3-73.466000109.3I245 F246 V247 K248 L285 I286 F287 L292 I303I245-L309 HydrophobicContact CB-CD1 4.48Å; I245-L309 HydrophobicContact CD1-CD1 4.15Å; I245-L309 HydrophobicContact CD1-CD2 4.27Å; F246-L309 PolarHBondContact O-N 2.9Å; V247-L309 CarbonylContact C-O 3.51Å; V247-L309 WeakPolarHBondContact CA-O 3.33Å; V247-L309 HydrophobicContact CG2-CB 4.38Å; K248-L309 PolarHBondContact N-O 3.36Å; L285-L309 HydrophobicContact CB-CD2 4.48Å; L285-L309 HydrophobicContact CD1-CD2 4.35Å; I286-L309 CarbonylContact O-C 3.57Å; I286-L309 WeakPolarHBondContact O-CA 3.26Å; F287-L309 HydrophobicContact CB-CG 4.26Å; F287-L309 HydrophobicContact CD2-CD1 4.04Å; F287-L309 HydrophobicContact CD2-CG 4.29Å; L292-L309 HydrophobicContact CD1-CD2 3.53Å; L292-L309 HydrophobicContact CD1-CG 4.19Å; I303-L309 HydrophobicContact CD1-CD1 4.3Å; I303-L309 HydrophobicContact CD1-CD2 4.34Å; I303-L309 HydrophobicContact CG2-CD1 4.04Å
310H96.6Very high87.3Confident95 Ų9572.4 Ų72.444%0.4436%0.355SS..EExtended strand (participates in β ladder)trans-107.5128.3172.9-65.373.1000109.4K248 I286K248-H310 CarbonylContact O-C 3.57Å; K248-H310 WeakPolarHBondContact O-CA 3.33Å; I286-H310 HydrophobicContact CB-CB 4.34Å; I286-H310 PolarHBondContact N-O 3.22Å; I286-H310 PolarHBondContact O-N 2.9Å
311L94.8Very high87.4Confident3 Ų367.8 Ų67.82%0.01633%0.331CS..EExtended strand (participates in β ladder)trans-97.7119.5175.1176.562.2000109.9V247 K248 T249 I272 I278 Q283 L285 L313V247-L311 HydrophobicContact CG1-CB 3.53Å; V247-L311 HydrophobicContact CG1-CD2 4.34Å; V247-L311 HydrophobicContact CG1-CG 4.5Å; K248-L311 PolarHBondContact O-N 3.3Å; T249-L311 HydrophobicContact CG2-CD2 4.44Å; I272-L311 HydrophobicContact CG2-CD2 4.12Å; I278-L311 HydrophobicContact CD1-CD2 4.19Å; Q283-L311 HydrophobicContact CB-CD1 3.78Å; Q283-L311 HydrophobicContact CG-CD1 3.99Å; L285-L311 HydrophobicContact CD2-CB 4.24Å; L285-L311 HydrophobicContact CD2-CD1 3.92Å; L311-L313 HydrophobicContact CD1-CD2 4.14Å; L311-L313 HydrophobicContact CD2-CD2 4.01Å; L311-L313 HydrophobicContact CG-CD2 3.96Å
312V90.4Very high87.4Confident40 Ų4068.6 Ų68.624%0.24234%0.335CS..EExtended strand (participates in β ladder)trans-110.2124.3170.9179.80000108.3L250 R284 I286L250-V312 HydrophobicContact CD1-CG1 4.32Å; L250-V312 HydrophobicContact CD1-CG2 4.43Å; L250-V312 HydrophobicContact CD2-CG2 4.41Å; R284-V312 HydrophobicContact CB-CB 4.3Å; R284-V312 VanDerWaalsContact CB-O 3.27Å; R284-V312 WeakPolarHBondContact CB-O 3.1Å; R284-V312 PolarHBondContact N-O 3.29Å; R284-V312 PolarHBondContact O-N 3.29Å; I286-V312 HydrophobicContact CD1-CG2 3.73Å
313L86.5Confident87.6Confident86 Ų8663.1 Ų63.145%0.4531%0.306SS..EExtended strand (participates in β ladder)trans-85.5130179.4-59.4-178.7000110.8I278 Q282 L311I278-L313 HydrophobicContact CD1-CD1 4.39Å; I278-L313 HydrophobicContact CD1-CD2 4.02Å; I278-L313 HydrophobicContact CG2-CD2 3.61Å; Q282-L313 CarbonylContact O-C 3.48Å; Q282-L313 WeakPolarHBondContact O-CA 3.48Å; L311-L313 HydrophobicContact CD1-CD2 4.14Å; L311-L313 HydrophobicContact CD2-CD2 4.01Å; L311-L313 HydrophobicContact CG-CD2 3.96Å
314R78.3Confident87.7Confident115 Ų11567 Ų6743%0.43432%0.322SS..  trans-86.1122.5170.3-71.6178.2144.5174.7-5.4108.8Q282 R316Q282-R314 PolarHBondContact O-N 2.98Å; R314-R316 VanDerWaalsContact C-N 3.3Å; R314-R316 PolarHBondContact O-N 2.99Å
315L66.6Low87.7Confident160 Ų16062.6 Ų62.684%0.83830%0.304SS*.THydrogen-bonded Turntrans-72.9-15.5-177.7-67170.8000114.6
316R62.5Low87.4Confident210 Ų21062.8 Ų62.879%0.79231%0.31SS*.THydrogen-bonded Turntrans-152.136.2-172.3-64.1-169.5-175.3-176.11.8114.3R314R314-R316 VanDerWaalsContact C-N 3.3Å; R314-R316 PolarHBondContact O-N 2.99Å
317G59.6Low87.1Confident41 Ų4162.8 Ų62.842%0.42332%0.319SS..  trans-80-21.6-174.500000115
318G73.5Confident86.6Confident5 Ų563.8 Ų63.85%0.05233%0.333CS..SBendtrans-101-176.1-160.100000116.8D281 Q320D281-G318 WeakPolarHBondContact OD2-CA 3.07Å; G318-Q320 PolarHBondContact O-N 2.75Å
319M88.3Confident86.5Confident29 Ų2966.3 Ų66.314%0.14334%0.339CS..EExtended strand (participates in β ladder)trans-69.2113.6167.5168.7169.5160.100108.3I321 V335 P337 L374 I379 K381M319-I321 HydrophobicContact CE-CG2 4.07Å; M319-V335 WeakPolarHBondContact CB-O 3.27Å; M319-V335 HydrophobicContact CE-CG2 4.22Å; M319-V335 HydrophobicContact CG-CG2 4.05Å; M319-V335 WeakPolarHBondContact O-CG2 3.45Å; M319-V335 PolarHBondContact O-N 2.97Å; M319-P337 HydrophobicContact SD-CG 3.83Å; M319-L374 HydrophobicContact CE-CD1 4.35Å; M319-I379 WeakPolarHBondContact CE-O 3.31Å; M319-K381 HydrophobicContact CG-CB 4.1Å
320Q90.4Very high86.4Confident35 Ų3569.7 Ų69.716%0.16436%0.36CS..EExtended strand (participates in β ladder)trans-97.4142174.8-69.6175.49.700110G318 T332 L333 E334 E382G318-Q320 PolarHBondContact O-N 2.75Å; Q320-T332 HydrophobicContact CB-CG2 4.25Å; Q320-T332 HydrophobicContact CG-CG2 4.26Å; Q320-L333 CarbonylContact C-O 3.6Å; Q320-L333 VanDerWaalsContact CA-O 3.26Å; Q320-L333 WeakPolarHBondContact CA-O 3.42Å; Q320-E334 VanDerWaalsContact CG-CD 3.49Å; Q320-E334 VanDerWaalsContact CG-OE1 3.29Å; Q320-E334 WeakPolarHBondContact CG-OE1 3.21Å; Q320-E334 WeakPolarHBondContact CG-OE2 3.37Å; Q320-E334 PolarHBondContact NE2-OE1 2.97Å; Q320-E382 PolarHBondContact O-N 2.96Å
321I95.5Very high86.3Confident0 Ų065.5 Ų65.50%034%0.341CS..EExtended strand (participates in β ladder)trans-123.8160.2164.963.5171.7000109.5M319 L333 V335 V344 L374 I379 L385M319-I321 HydrophobicContact CE-CG2 4.07Å; I321-L333 HydrophobicContact CG1-CB 4.05Å; I321-L333 PolarHBondContact N-O 3.45Å; I321-L333 PolarHBondContact O-N 3.09Å; I321-V335 HydrophobicContact CB-CG2 4.32Å; I321-V335 HydrophobicContact CD1-CG1 3.9Å; I321-V335 HydrophobicContact CD1-CG2 4.07Å; I321-V335 HydrophobicContact CG1-CG1 3.92Å; I321-V335 HydrophobicContact CG1-CG2 3.82Å; I321-V335 HydrophobicContact CG2-CG2 3.75Å; I321-V344 HydrophobicContact CD1-CG1 4.22Å; I321-L374 HydrophobicContact CD1-CD1 4.19Å; I321-L374 HydrophobicContact CD1-CD2 4.28Å; I321-I379 HydrophobicContact CG2-CG2 3.99Å; I321-L385 HydrophobicContact CD1-CD1 4.3Å; I321-L385 HydrophobicContact CD1-CD2 4.28Å
322F97.3Very high86.2Confident55 Ų5567.9 Ų67.924%0.24136%0.355CS..EExtended strand (participates in β ladder)trans-111.1135.2178.1-57.7-74.2000110T330 I331 T332 E382 S383 T384 L385F322-T330 HydrophobicContact CB-CG2 3.86Å; F322-T330 HydrophobicContact CD1-CG2 3.97Å; F322-T330 HydrophobicContact CG-CG2 4.28Å; F322-I331 CarbonylContact C-O 3.47Å; F322-I331 WeakPolarHBondContact CA-O 3.47Å; F322-T332 HydrophobicContact CD1-CG2 4.3Å; F322-T332 HydrophobicContact CE1-CG2 4.01Å; F322-E382 WeakPolarHBondContact CD2-O 3.4Å; F322-E382 HydrophobicContact CE2-CB 3.89Å; F322-E382 HydrophobicContact CE2-CG 3.94Å; F322-S383 PolarHBondContact N-O 2.91Å; F322-T384 HydrophobicContact CB-CG2 4.46Å; F322-T384 CarbonylContact O-C 3.59Å; F322-T384 VanDerWaalsContact O-CA 3.3Å; F322-T384 WeakPolarHBondContact O-CA 3.45Å; F322-L385 PolarHBondContact O-N 2.94Å
323V97.4Very high86.2Confident0 Ų066 Ų660%034%0.344CS..EExtended strand (participates in β ladder)trans-115.4111.5174.4-178.80000108.3I331 L333 I348 L361 L385 L387V323-I331 HydrophobicContact CB-CB 4.34Å; V323-I331 PolarHBondContact N-O 2.97Å; V323-I331 PolarHBondContact O-N 3.46Å; V323-L333 HydrophobicContact CG2-CD1 3.53Å; V323-L333 HydrophobicContact CG2-CG 4.17Å; V323-I348 HydrophobicContact CG1-CD1 4.09Å; V323-I348 HydrophobicContact CG2-CD1 4.13Å; V323-L361 HydrophobicContact CG1-CD2 4.05Å; V323-L385 CarbonylContact C-O 3.5Å; V323-L385 WeakPolarHBondContact CA-O 3.24Å; V323-L385 HydrophobicContact CG2-CB 4.33Å; V323-L387 HydrophobicContact CG1-CB 3.53Å; V323-L387 HydrophobicContact CG1-CD2 4.43Å
324K96.8Very high86.3Confident88 Ų8863.4 Ų63.438%0.38333%0.33SS..EExtended strand (participates in β ladder)trans-96.7123.6-179.3-155.8174.1-172.7178.60110.1T384 L385 H386 L387K324-T384 HydrophobicContact CB-CG2 4.03Å; K324-L385 PolarHBondContact N-O 2.9Å; K324-H386 CarbonylContact O-C 3.59Å; K324-H386 WeakPolarHBondContact O-CA 3.44Å; K324-L387 PolarHBondContact O-N 3.5Å
325T92.4Very high86.9Confident25 Ų2558.1 Ų58.115%0.15331%0.31CS..EExtended strand (participates in β ladder)trans-80.3162.4175.265.10000110.9T327 G328 K329 I331 L387T325-T327 PolarHBondContact O-N 2.71Å; T325-T327 PolarHBondContact OG1-OG1 3.32Å; T325-G328 PolarHBondContact O-N 3.05Å; T325-K329 HydrophobicContact CG2-CB 4.45Å; T325-K329 PolarHBondContact N-O 3.43Å; T325-K329 WeakPolarHBondContact OG1-CB 3.32Å; T325-K329 PolarHBondContact OG1-N 3.41Å; T325-K329 VanDerWaalsContact OG1-N 3.13Å; T325-K329 PolarHBondContact OG1-O 3.01Å; T325-I331 HydrophobicContact CG2-CD1 3.94Å; T325-L387 HydrophobicContact CG2-CD2 4.34Å
326L86.3Confident87.9Confident136 Ų13652.4 Ų52.471%0.71228%0.279SS*.THydrogen-bonded Turntrans-62.3-21.8174.1-68.6178.3000113.9G328 V388L326-G328 PolarHBondContact O-N 3.23Å; L326-V388 HydrophobicContact CD1-CG1 4.18Å; L326-V388 HydrophobicContact CD1-CG2 4.38Å; L326-V388 HydrophobicContact CD2-CG2 4.25Å; L326-V388 HydrophobicContact CG-CG2 4.38Å
327T86.4Confident89.4Confident127 Ų12745.6 Ų45.678%0.77926%0.262SS*.THydrogen-bonded Turntrans-80.2-4.4175.262.20000112.7T325T325-T327 PolarHBondContact O-N 2.71Å; T325-T327 PolarHBondContact OG1-OG1 3.32Å
328G86.2Confident90.9Very high41 Ų4147.1 Ų47.142%0.42327%0.267SS..SBendtrans90.3-6.3-177.800000114.6T325 L326 T330T325-G328 PolarHBondContact O-N 3.05Å; L326-G328 PolarHBondContact O-N 3.23Å; G328-T330 PolarHBondContact O-N 3.27Å
329K94.3Very high91.8Very high101 Ų10147.6 Ų47.644%0.43927%0.268SS..  trans-64.3132.1173.1-178.2-178.3176.4-174.20109.9T325 E352T325-K329 HydrophobicContact CG2-CB 4.45Å; T325-K329 PolarHBondContact N-O 3.43Å; T325-K329 WeakPolarHBondContact OG1-CB 3.32Å; T325-K329 PolarHBondContact OG1-N 3.41Å; T325-K329 VanDerWaalsContact OG1-N 3.13Å; T325-K329 PolarHBondContact OG1-O 3.01Å; K329-E352 WeakPolarHBondContact CE-OE1 3.44Å; K329-E352 IonicContact NZ-OE1 3.81Å; K329-E352 PolarHBondContact NZ-OE1 2.9Å; K329-E352 IonicContact NZ-OE2 3.85Å; K329-E352 PolarHBondContact NZ-OE2 3.1Å
330T94.8Very high92.1Very high71 Ų7147.9 Ų47.944%0.43627%0.271SS..EExtended strand (participates in β ladder)trans-105.9127.9174.8-570000109.9F322 G328F322-T330 HydrophobicContact CB-CG2 3.86Å; F322-T330 HydrophobicContact CD1-CG2 3.97Å; F322-T330 HydrophobicContact CG-CG2 4.28Å; G328-T330 PolarHBondContact O-N 3.27Å
331I93.4Very high92.4Very high7 Ų746.2 Ų46.24%0.03626%0.263CS..EExtended strand (participates in β ladder)trans-106.6128.3176.3-55.8149.6000107.5F322 V323 T325 L333 K351 E352F322-I331 CarbonylContact C-O 3.47Å; F322-I331 WeakPolarHBondContact CA-O 3.47Å; V323-I331 HydrophobicContact CB-CB 4.34Å; V323-I331 PolarHBondContact N-O 2.97Å; V323-I331 PolarHBondContact O-N 3.46Å; T325-I331 HydrophobicContact CG2-CD1 3.94Å; I331-L333 HydrophobicContact CG2-CD2 3.92Å; I331-L333 HydrophobicContact CG2-CG 4.43Å; I331-K351 HydrophobicContact CG2-CD 4.19Å; I331-E352 HydrophobicContact CD1-CG 3.6Å; I331-E352 HydrophobicContact CG1-CG 3.97Å; I331-E352 HydrophobicContact CG2-CG 4.48Å
332T93.2Very high92.3Very high53 Ų5351.4 Ų51.433%0.32529%0.288SS..EExtended strand (participates in β ladder)trans-92.4128.1173.7-54.10000109.6Q320 F322 K351Q320-T332 HydrophobicContact CB-CG2 4.25Å; Q320-T332 HydrophobicContact CG-CG2 4.26Å; F322-T332 HydrophobicContact CD1-CG2 4.3Å; F322-T332 HydrophobicContact CE1-CG2 4.01Å; T332-K351 PolarHBondContact O-NZ 3.21Å
333L91.1Very high92Very high1 Ų152.2 Ų52.21%0.00529%0.294CS..EExtended strand (participates in β ladder)trans-117139.2176.4-58.6178.2000110.3Q320 I321 V323 I331 V335 V344 K347 I348 K351Q320-L333 CarbonylContact C-O 3.6Å; Q320-L333 VanDerWaalsContact CA-O 3.26Å; Q320-L333 WeakPolarHBondContact CA-O 3.42Å; I321-L333 HydrophobicContact CG1-CB 4.05Å; I321-L333 PolarHBondContact N-O 3.45Å; I321-L333 PolarHBondContact O-N 3.09Å; V323-L333 HydrophobicContact CG2-CD1 3.53Å; V323-L333 HydrophobicContact CG2-CG 4.17Å; I331-L333 HydrophobicContact CG2-CD2 3.92Å; I331-L333 HydrophobicContact CG2-CG 4.43Å; L333-V335 HydrophobicContact CB-CG1 4Å; L333-V344 HydrophobicContact CD1-CG1 3.83Å; L333-K347 HydrophobicContact CD2-CB 4.31Å; L333-I348 HydrophobicContact CD1-CD1 4.09Å; L333-I348 HydrophobicContact CD1-CG1 3.55Å; L333-I348 HydrophobicContact CD2-CG1 4.3Å; L333-I348 HydrophobicContact CG-CG1 4.48Å; L333-K351 HydrophobicContact CD2-CD 3.98Å
334E88Confident92Very high32 Ų3252.2 Ų52.215%0.1529%0.294CS..EExtended strand (participates in β ladder)trans-91.6122.1167.9-62.7-74.6167.300107.9Q282 Q320 K347Q282-E334 VanDerWaalsContact NE2-CB 3.34Å; Q320-E334 VanDerWaalsContact CG-CD 3.49Å; Q320-E334 VanDerWaalsContact CG-OE1 3.29Å; Q320-E334 WeakPolarHBondContact CG-OE1 3.21Å; Q320-E334 WeakPolarHBondContact CG-OE2 3.37Å; Q320-E334 PolarHBondContact NE2-OE1 2.97Å; E334-K347 PolarHBondContact O-NZ 2.89Å
335V90.6Very high91.8Very high4 Ų448.4 Ų48.42%0.02428%0.278CS..EExtended strand (participates in β ladder)trans-139.5159.5-171.1-61.90000111.1M319 I321 L333 D339 V344 K347 L374M319-V335 WeakPolarHBondContact CB-O 3.27Å; M319-V335 HydrophobicContact CE-CG2 4.22Å; M319-V335 HydrophobicContact CG-CG2 4.05Å; M319-V335 WeakPolarHBondContact O-CG2 3.45Å; M319-V335 PolarHBondContact O-N 2.97Å; I321-V335 HydrophobicContact CB-CG2 4.32Å; I321-V335 HydrophobicContact CD1-CG1 3.9Å; I321-V335 HydrophobicContact CD1-CG2 4.07Å; I321-V335 HydrophobicContact CG1-CG1 3.92Å; I321-V335 HydrophobicContact CG1-CG2 3.82Å; I321-V335 HydrophobicContact CG2-CG2 3.75Å; L333-V335 HydrophobicContact CB-CG1 4Å; V335-D339 VanDerWaalsContact CA-OD2 3.27Å; V335-D339 WeakPolarHBondContact CA-OD2 3.41Å; V335-D339 WeakPolarHBondContact CB-OD2 3.43Å; V335-V344 HydrophobicContact CG1-CG2 4.29Å; V335-K347 HydrophobicContact CG1-CD 4.16Å; V335-L374 HydrophobicContact CB-CD1 3.59Å; V335-L374 HydrophobicContact CG1-CD1 4.13Å; V335-L374 HydrophobicContact CG2-CD1 3.44Å; V335-L374 VanDerWaalsContact CG2-CD1 3.44Å
336E88.6Confident91.7Very high39 Ų3949.8 Ų49.818%0.18229%0.287CS..  trans-106151168.8-66.5178.1177.900110Q273 P280 S338 D339Q273-E336 PolarHBondContact NE2-OE1 3.43Å; Q273-E336 VanDerWaalsContact NE2-OE1 3.14Å; P280-E336 WeakPolarHBondContact CD-OE1 3.43Å; E336-S338 PolarHBondContact O-N 2.9Å; E336-S338 VanDerWaalsContact O-N 3.1Å; E336-D339 PolarHBondContact N-OD2 3.18Å; E336-D339 VanDerWaalsContact O-CB 3.3Å; E336-D339 WeakPolarHBondContact O-CB 3.35Å; E336-D339 PolarHBondContact O-N 3.47Å
337P92.2Very high92Very high67 Ų6745.8 Ų45.844%0.43526%0.263SS..THydrogen-bonded Turntrans-55.8-28.6175.1-24.733000113.8M319 S375M319-P337 HydrophobicContact SD-CG 3.83Å; P337-S375 WeakPolarHBondContact O-CB 3.25Å; P337-S375 PolarHBondContact O-N 2.92Å; P337-S375 PolarHBondContact O-OG 3.3Å
338S91.5Very high92.4Very high74 Ų7439.7 Ų39.752%0.51723%0.226SC..THydrogen-bonded Turntrans-77.7-1217638.50000114.2E336 T340 T373E336-S338 PolarHBondContact O-N 2.9Å; E336-S338 VanDerWaalsContact O-N 3.1Å; S338-T340 PolarHBondContact O-N 3.42Å; S338-T373 WeakPolarHBondContact O-CG2 3.2Å
339D92.2Very high92.6Very high14 Ų1440.6 Ų40.68%0.07522%0.219CC..  trans-60130.1179.4-87.2-34.3000110.3V335 E336 N343 V344 K347 T373 L374V335-D339 VanDerWaalsContact CA-OD2 3.27Å; V335-D339 WeakPolarHBondContact CA-OD2 3.41Å; V335-D339 WeakPolarHBondContact CB-OD2 3.43Å; E336-D339 PolarHBondContact N-OD2 3.18Å; E336-D339 VanDerWaalsContact O-CB 3.3Å; E336-D339 WeakPolarHBondContact O-CB 3.35Å; E336-D339 PolarHBondContact O-N 3.47Å; D339-N343 HydrophobicContact CB-CB 4.27Å; D339-N343 PolarHBondContact OD1-ND2 3.24Å; D339-V344 HydrophobicContact CB-CG2 4.28Å; D339-K347 VanDerWaalsContact OD2-CE 3.23Å; D339-K347 WeakPolarHBondContact OD2-CE 3.45Å; D339-K347 IonicContact OD2-NZ 3.49Å; D339-K347 PolarHBondContact OD2-NZ 3.17Å; D339-T373 CarbonylContact O-C 3.58Å; D339-T373 WeakPolarHBondContact O-CA 3.41Å; D339-L374 HydrophobicContact CB-CD1 4.27Å; D339-L374 HydrophobicContact CB-CG 4.49Å; D339-L374 PolarHBondContact O-N 2.83Å
340T95.6Very high92.2Very high35 Ų3541.7 Ų41.722%0.21523%0.23CC..BIsolated β-bridgetrans-70.7158.3170.464.80000110.5S338 E342 N343 V344 R372S338-T340 PolarHBondContact O-N 3.42Å; T340-E342 PolarHBondContact O-N 2.86Å; T340-N343 WeakPolarHBondContact O-CB 3.23Å; T340-N343 PolarHBondContact O-N 2.65Å; T340-N343 VanDerWaalsContact O-N 3.09Å; T340-N343 PolarHBondContact OG1-N 3.35Å; T340-N343 VanDerWaalsContact OG1-N 3.09Å; T340-N343 PolarHBondContact OG1-OD1 2.67Å; T340-N343 VanDerWaalsContact OG1-OD1 3.09Å; T340-V344 WeakPolarHBondContact O-CG2 3.47Å; T340-V344 PolarHBondContact O-N 3.4Å; T340-R372 CarbonylContact C-O 3.55Å; T340-R372 VanDerWaalsContact CA-O 3.24Å; T340-R372 WeakPolarHBondContact CA-O 3.42Å
341I96.4Very high91.9Very high0 Ų044 Ų440%023%0.234CC..Hα-helixtrans-62.4-30.9174.5-60.6-56.4000111.2V344 K345 L361 L368 E369 D370 R372 L374 Y377I341-V344 PolarHBondContact O-N 2.93Å; I341-K345 WeakPolarHBondContact O-CG 3.19Å; I341-K345 PolarHBondContact O-N 3.4Å; I341-L361 HydrophobicContact CG2-CD1 4.18Å; I341-L368 HydrophobicContact CD1-CB 3.95Å; I341-L368 HydrophobicContact CD1-CD1 3.58Å; I341-L368 HydrophobicContact CD1-CG 4.31Å; I341-L368 HydrophobicContact CG1-CB 3.89Å; I341-L368 HydrophobicContact CG1-CD1 4.46Å; I341-L368 HydrophobicContact CG2-CB 3.89Å; I341-E369 WeakPolarHBondContact CB-O 2.88Å; I341-E369 VanDerWaalsContact CG1-O 3.28Å; I341-E369 WeakPolarHBondContact CG1-O 3.5Å; I341-D370 PolarHBondContact N-O 2.93Å; I341-R372 WeakPolarHBondContact CG1-O 3.33Å; I341-R372 PolarHBondContact N-O 3.04Å; I341-L374 HydrophobicContact CD1-CD2 3.96Å; I341-Y377 HydrophobicContact CD1-CD2 4.39Å; I341-Y377 HydrophobicContact CD1-CE2 4.48Å; I341-Y377 HydrophobicContact CG1-CD2 4.49Å; I341-Y377 HydrophobicContact CG1-CE2 4.13Å
342E93.2Very high91.7Very high109 Ų10946.9 Ų46.951%0.50925%0.247SC..Hα-helixtrans-62.5-43.9170.2-170170.7-162.700112.8T340 V344 K345 T346 D370T340-E342 PolarHBondContact O-N 2.86Å; E342-V344 VanDerWaalsContact C-N 3.31Å; E342-V344 PolarHBondContact O-N 2.73Å; E342-K345 WeakPolarHBondContact O-CB 3.4Å; E342-K345 PolarHBondContact O-N 2.72Å; E342-T346 PolarHBondContact O-N 3.01Å; E342-T346 PolarHBondContact O-OG1 2.81Å; E342-D370 HydrophobicContact CB-CB 4.27Å; E342-D370 PolarHBondContact N-O 3.09Å; E342-D370 VanDerWaalsContact N-O 3.15Å
343N92.1Very high91.4Very high72 Ų7247.2 Ų47.239%0.38526%0.261SS..Hα-helixtrans-59.2-44.1173.2-67.5-1.1000111D339 T340 K345 T346 K347D339-N343 HydrophobicContact CB-CB 4.27Å; D339-N343 PolarHBondContact OD1-ND2 3.24Å; T340-N343 WeakPolarHBondContact O-CB 3.23Å; T340-N343 PolarHBondContact O-N 2.65Å; T340-N343 VanDerWaalsContact O-N 3.09Å; T340-N343 PolarHBondContact OG1-N 3.35Å; T340-N343 VanDerWaalsContact OG1-N 3.09Å; T340-N343 PolarHBondContact OG1-OD1 2.67Å; T340-N343 VanDerWaalsContact OG1-OD1 3.09Å; N343-K345 VanDerWaalsContact C-N 3.32Å; N343-K345 PolarHBondContact O-N 3.28Å; N343-T346 WeakPolarHBondContact O-CB 3.41Å; N343-T346 PolarHBondContact O-N 3.46Å; N343-K347 WeakPolarHBondContact O-CG 3.31Å; N343-K347 PolarHBondContact O-N 3.45Å
344V95.5Very high91.1Very high0 Ų048.5 Ų48.50%027%0.268CS..Hα-helixtrans-62-41.3178.1177.60000111I321 L333 V335 D339 T340 I341 E342 K347 I348 L361 L374I321-V344 HydrophobicContact CD1-CG1 4.22Å; L333-V344 HydrophobicContact CD1-CG1 3.83Å; V335-V344 HydrophobicContact CG1-CG2 4.29Å; D339-V344 HydrophobicContact CB-CG2 4.28Å; T340-V344 WeakPolarHBondContact O-CG2 3.47Å; T340-V344 PolarHBondContact O-N 3.4Å; I341-V344 PolarHBondContact O-N 2.93Å; E342-V344 VanDerWaalsContact C-N 3.31Å; E342-V344 PolarHBondContact O-N 2.73Å; V344-K347 PolarHBondContact O-N 3.35Å; V344-I348 HydrophobicContact CG1-CD1 4.31Å; V344-I348 WeakPolarHBondContact O-CG1 3.29Å; V344-I348 PolarHBondContact O-N 3.21Å; V344-L361 HydrophobicContact CB-CD1 4.32Å; V344-L361 HydrophobicContact CG1-CD1 3.76Å; V344-L374 HydrophobicContact CG2-CD1 4.09Å; V344-L374 HydrophobicContact CG2-CD2 4.01Å; V344-L374 HydrophobicContact CG2-CG 4.11Å
345K94.2Very high90.8Very high8 Ų848 Ų484%0.03527%0.268CS..Hα-helixtrans-63.7-41175.8-73.9172.1163.2-169.10112.5I341 E342 N343 K347 I348 Q349 P356 Q359 L361 D370I341-K345 WeakPolarHBondContact O-CG 3.19Å; I341-K345 PolarHBondContact O-N 3.4Å; E342-K345 WeakPolarHBondContact O-CB 3.4Å; E342-K345 PolarHBondContact O-N 2.72Å; N343-K345 VanDerWaalsContact C-N 3.32Å; N343-K345 PolarHBondContact O-N 3.28Å; K345-K347 VanDerWaalsContact C-N 3.35Å; K345-I348 WeakPolarHBondContact O-CB 3.37Å; K345-I348 PolarHBondContact O-N 2.75Å; K345-I348 VanDerWaalsContact O-N 3.14Å; K345-Q349 PolarHBondContact O-N 3.36Å; K345-P356 HydrophobicContact CB-CB 3.85Å; K345-P356 HydrophobicContact CB-CG 4.36Å; K345-P356 HydrophobicContact CD-CB 4.2Å; K345-P356 PolarHBondContact NZ-O 3.44Å; K345-Q359 HydrophobicContact CD-CB 4.38Å; K345-Q359 WeakPolarHBondContact CE-O 3.43Å; K345-Q359 HydrophobicContact CG-CB 4.06Å; K345-Q359 PolarHBondContact NZ-O 2.84Å; K345-Q359 PolarHBondContact O-NE2 3.35Å; K345-Q359 PolarHBondContact O-OE1 3.26Å; K345-L361 HydrophobicContact CG-CD1 3.95Å; K345-L361 HydrophobicContact CG-CG 4.47Å; K345-D370 WeakPolarHBondContact CE-OD1 3.31Å; K345-D370 VanDerWaalsContact NZ-CG 3.26Å; K345-D370 IonicContact NZ-OD1 2.89Å; K345-D370 PolarHBondContact NZ-OD1 2.94Å; K345-D370 IonicContact NZ-OD2 2.9Å; K345-D370 PolarHBondContact NZ-OD2 3.32Å
346T90.6Very high90.7Very high55 Ų5548.5 Ų48.534%0.33727%0.271SS..Hα-helixtrans-60.4-45.7174.5-52.70000110.5E342 N343 I348 Q349 D350E342-T346 PolarHBondContact O-N 3.01Å; E342-T346 PolarHBondContact O-OG1 2.81Å; N343-T346 WeakPolarHBondContact O-CB 3.41Å; N343-T346 PolarHBondContact O-N 3.46Å; T346-I348 PolarHBondContact O-N 3.36Å; T346-Q349 WeakPolarHBondContact O-CA 3.49Å; T346-Q349 VanDerWaalsContact O-CB 3.28Å; T346-Q349 WeakPolarHBondContact O-CB 3.23Å; T346-Q349 PolarHBondContact O-N 3.45Å; T346-D350 VanDerWaalsContact O-CG 3.31Å; T346-D350 PolarHBondContact O-N 3.31Å
347K92.5Very high90.3Very high51 Ų5148.5 Ų48.522%0.22227%0.272CS..Hα-helixtrans-60.4-30.9174.7-67.9169.2-172.1-101.40113.3L333 E334 V335 D339 N343 V344 K345 K351L333-K347 HydrophobicContact CD2-CB 4.31Å; E334-K347 PolarHBondContact O-NZ 2.89Å; V335-K347 HydrophobicContact CG1-CD 4.16Å; D339-K347 VanDerWaalsContact OD2-CE 3.23Å; D339-K347 WeakPolarHBondContact OD2-CE 3.45Å; D339-K347 IonicContact OD2-NZ 3.49Å; D339-K347 PolarHBondContact OD2-NZ 3.17Å; N343-K347 WeakPolarHBondContact O-CG 3.31Å; N343-K347 PolarHBondContact O-N 3.45Å; V344-K347 PolarHBondContact O-N 3.35Å; K345-K347 VanDerWaalsContact C-N 3.35Å; K347-K351 PolarHBondContact O-N 2.98Å
348I93.9Very high89.9Confident0 Ų047.2 Ų47.20%026%0.26CS..Hα-helixtrans-72.5-42173-66.5163.4000110.5V323 L333 V344 K345 T346 D350 K351 E352 Q359 L361 L387V323-I348 HydrophobicContact CG1-CD1 4.09Å; V323-I348 HydrophobicContact CG2-CD1 4.13Å; L333-I348 HydrophobicContact CD1-CD1 4.09Å; L333-I348 HydrophobicContact CD1-CG1 3.55Å; L333-I348 HydrophobicContact CD2-CG1 4.3Å; L333-I348 HydrophobicContact CG-CG1 4.48Å; V344-I348 HydrophobicContact CG1-CD1 4.31Å; V344-I348 WeakPolarHBondContact O-CG1 3.29Å; V344-I348 PolarHBondContact O-N 3.21Å; K345-I348 WeakPolarHBondContact O-CB 3.37Å; K345-I348 PolarHBondContact O-N 2.75Å; K345-I348 VanDerWaalsContact O-N 3.14Å; T346-I348 PolarHBondContact O-N 3.36Å; I348-D350 VanDerWaalsContact C-N 3.31Å; I348-D350 PolarHBondContact O-N 3.31Å; I348-K351 PolarHBondContact O-N 3.47Å; I348-E352 WeakPolarHBondContact O-CB 3.43Å; I348-E352 PolarHBondContact O-N 2.73Å; I348-Q359 VanDerWaalsContact CD1-OE1 3.28Å; I348-L361 HydrophobicContact CD1-CD1 4.02Å; I348-L361 HydrophobicContact CD1-CD2 3.71Å; I348-L361 HydrophobicContact CD1-CG 4.37Å; I348-L387 HydrophobicContact CG2-CD2 4.07Å
349Q90.1Very high89.9Confident60 Ų6043.7 Ų43.728%0.2824%0.236SC..Hα-helixtrans-57.9-46.3175.2-177.3-176.314.200110.7K345 T346 K351 E352 G353 I354 P356K345-Q349 PolarHBondContact O-N 3.36Å; T346-Q349 WeakPolarHBondContact O-CA 3.49Å; T346-Q349 VanDerWaalsContact O-CB 3.28Å; T346-Q349 WeakPolarHBondContact O-CB 3.23Å; T346-Q349 PolarHBondContact O-N 3.45Å; Q349-K351 VanDerWaalsContact C-N 3.25Å; Q349-K351 PolarHBondContact O-N 3Å; Q349-E352 PolarHBondContact O-N 3.02Å; Q349-G353 WeakPolarHBondContact O-CA 2.87Å; Q349-G353 PolarHBondContact O-N 3.07Å; Q349-I354 VanDerWaalsContact CA-O 3.27Å; Q349-I354 WeakPolarHBondContact CA-O 3.19Å; Q349-I354 WeakPolarHBondContact CB-O 3.12Å; Q349-P356 VanDerWaalsContact OE1-CD 3.25Å
350D85.8Confident89.9Confident123 Ų12347.8 Ų47.866%0.65825%0.25SC*.Hα-helixtrans-60.6-35.5179.5-63.8-25.3000112.5T346 I348T346-D350 VanDerWaalsContact O-CG 3.31Å; T346-D350 PolarHBondContact O-N 3.31Å; I348-D350 VanDerWaalsContact C-N 3.31Å; I348-D350 PolarHBondContact O-N 3.31Å
351K89Confident89.9Confident121 Ų12146.2 Ų46.253%0.52624%0.24SC..Hα-helixtrans-86-35-178.6-75.4-158.9178-166.50114.7I331 T332 L333 K347 I348 Q349I331-K351 HydrophobicContact CG2-CD 4.19Å; T332-K351 PolarHBondContact O-NZ 3.21Å; L333-K351 HydrophobicContact CD2-CD 3.98Å; K347-K351 PolarHBondContact O-N 2.98Å; I348-K351 PolarHBondContact O-N 3.47Å; Q349-K351 VanDerWaalsContact C-N 3.25Å; Q349-K351 PolarHBondContact O-N 3Å
352E90.6Very high89.9Confident66 Ų6648.4 Ų48.431%0.30825%0.251SS..Hα-helixtrans-121.9-4.9-168-63.9-71.7144.400113.4K329 I331 I348 Q349 I354K329-E352 WeakPolarHBondContact CE-OE1 3.44Å; K329-E352 IonicContact NZ-OE1 3.81Å; K329-E352 PolarHBondContact NZ-OE1 2.9Å; K329-E352 IonicContact NZ-OE2 3.85Å; K329-E352 PolarHBondContact NZ-OE2 3.1Å; I331-E352 HydrophobicContact CD1-CG 3.6Å; I331-E352 HydrophobicContact CG1-CG 3.97Å; I331-E352 HydrophobicContact CG2-CG 4.48Å; I348-E352 WeakPolarHBondContact O-CB 3.43Å; I348-E352 PolarHBondContact O-N 2.73Å; Q349-E352 PolarHBondContact O-N 3.02Å; E352-I354 HydrophobicContact CB-CD1 3.91Å; E352-I354 HydrophobicContact CB-CG1 3.94Å; E352-I354 PolarHBondContact O-N 2.71Å
353G85.4Confident90.1Very high60 Ų6045.2 Ų45.262%0.61924%0.236SC*.  trans71.114.7-178.400000114.4Q349 P355Q349-G353 WeakPolarHBondContact O-CA 2.87Å; Q349-G353 PolarHBondContact O-N 3.07Å; G353-P355 WeakPolarHBondContact O-CD 3.45Å
354I85.1Confident90.2Very high28 Ų2846.3 Ų46.314%0.14426%0.255CS..  trans-92.2117.1-175.2-54.9174.8000109.4Q349 E352 Q358 Q359 L387 L389Q349-I354 VanDerWaalsContact CA-O 3.27Å; Q349-I354 WeakPolarHBondContact CA-O 3.19Å; Q349-I354 WeakPolarHBondContact CB-O 3.12Å; E352-I354 HydrophobicContact CB-CD1 3.91Å; E352-I354 HydrophobicContact CB-CG1 3.94Å; E352-I354 PolarHBondContact O-N 2.71Å; I354-Q358 HydrophobicContact CG2-CB 4.33Å; I354-Q359 HydrophobicContact CB-CG 4.48Å; I354-Q359 HydrophobicContact CG2-CG 3.77Å; I354-Q359 PolarHBondContact O-NE2 2.67Å; I354-L387 HydrophobicContact CD1-CD2 4.12Å; I354-L389 HydrophobicContact CD1-CD2 4.05Å; I354-L389 HydrophobicContact CG2-CD2 3.65Å
355P82.8Confident90Very high23 Ų2350 Ų5015%0.14929%0.293CS..  trans-60.8142.2-179.7-26.937.3000113.9G353 D357 Q358 Q359G353-P355 WeakPolarHBondContact O-CD 3.45Å; P355-D357 VanDerWaalsContact C-N 3.28Å; P355-D357 VanDerWaalsContact CB-OD1 3.26Å; P355-D357 WeakPolarHBondContact CB-OD1 3.29Å; P355-D357 PolarHBondContact O-N 2.84Å; P355-Q358 HydrophobicContact CB-CG 4.47Å; P355-Q358 WeakPolarHBondContact O-CB 3.45Å; P355-Q358 PolarHBondContact O-N 3.36Å; P355-Q358 VanDerWaalsContact O-N 3.08Å; P355-Q359 WeakPolarHBondContact O-CG 3.38Å
356P86.8Confident90Very high13 Ų1354.7 Ų54.78%0.08431%0.313CS..G310 helixtrans-55.2-33-175.8-30.937.6000115.8K345 Q349 Q358 Q359K345-P356 HydrophobicContact CB-CB 3.85Å; K345-P356 HydrophobicContact CB-CG 4.36Å; K345-P356 HydrophobicContact CD-CB 4.2Å; K345-P356 PolarHBondContact NZ-O 3.44Å; Q349-P356 VanDerWaalsContact OE1-CD 3.25Å; P356-Q358 VanDerWaalsContact C-N 3.33Å; P356-Q358 PolarHBondContact O-N 3.19Å; P356-Q359 WeakPolarHBondContact O-CB 3.32Å; P356-Q359 PolarHBondContact O-N 3.03Å; P356-Q359 VanDerWaalsContact O-N 3.15Å
357D80.4Confident90.2Very high39 Ų3956 Ų5621%0.20932%0.315CS..G310 helixtrans-70.1-27.1179.362.7-11.3000113.5P355 Q359 G394P355-D357 VanDerWaalsContact C-N 3.28Å; P355-D357 VanDerWaalsContact CB-OD1 3.26Å; P355-D357 WeakPolarHBondContact CB-OD1 3.29Å; P355-D357 PolarHBondContact O-N 2.84Å; D357-Q359 VanDerWaalsContact C-N 3.31Å; D357-G394 WeakPolarHBondContact OD2-CA 3.42Å
358Q84.9Confident90.4Very high41 Ų4153.7 Ų53.719%0.19231%0.306CS..G310 helixtrans-80-14.9172.2-61.7-173.60.500112.4I354 P355 P356 L389 R390 E410I354-Q358 HydrophobicContact CG2-CB 4.33Å; P355-Q358 HydrophobicContact CB-CG 4.47Å; P355-Q358 WeakPolarHBondContact O-CB 3.45Å; P355-Q358 PolarHBondContact O-N 3.36Å; P355-Q358 VanDerWaalsContact O-N 3.08Å; P356-Q358 VanDerWaalsContact C-N 3.33Å; P356-Q358 PolarHBondContact O-N 3.19Å; Q358-L389 CarbonylContact O-C 3.59Å; Q358-L389 WeakPolarHBondContact O-CA 3.41Å; Q358-R390 PolarHBondContact O-N 2.88Å; Q358-E410 PolarHBondContact NE2-OE1 3.26Å
359Q90.6Very high90.3Very high0 Ų058.1 Ų58.10%033%0.326CS..EExtended strand (participates in β ladder)trans-88.3124.6-176.3-59.8178.934.600111.8K345 I348 I354 P355 P356 D357 L387K345-Q359 HydrophobicContact CD-CB 4.38Å; K345-Q359 WeakPolarHBondContact CE-O 3.43Å; K345-Q359 HydrophobicContact CG-CB 4.06Å; K345-Q359 PolarHBondContact NZ-O 2.84Å; K345-Q359 PolarHBondContact O-NE2 3.35Å; K345-Q359 PolarHBondContact O-OE1 3.26Å; I348-Q359 VanDerWaalsContact CD1-OE1 3.28Å; I354-Q359 HydrophobicContact CB-CG 4.48Å; I354-Q359 HydrophobicContact CG2-CG 3.77Å; I354-Q359 PolarHBondContact O-NE2 2.67Å; P355-Q359 WeakPolarHBondContact O-CG 3.38Å; P356-Q359 WeakPolarHBondContact O-CB 3.32Å; P356-Q359 PolarHBondContact O-N 3.03Å; P356-Q359 VanDerWaalsContact O-N 3.15Å; D357-Q359 VanDerWaalsContact C-N 3.31Å; Q359-L387 HydrophobicContact CB-CD1 3.71Å; Q359-L387 HydrophobicContact CG-CD1 3.93Å
360R92.1Very high90.3Very high100 Ų10058.4 Ų58.438%0.37733%0.33SS..EExtended strand (participates in β ladder)trans-111.6110.2164.1-119.4-179.5178.3167.87.1109Q367 V388 R390R360-Q367 HydrophobicContact CG-CG 4.17Å; R360-Q367 VanDerWaalsContact NE-CD 3.33Å; R360-Q367 VanDerWaalsContact NH2-OE1 3.15Å; R360-V388 WeakPolarHBondContact CA-O 3.26Å; R360-V388 HydrophobicContact CB-CB 4.12Å; R360-V388 WeakPolarHBondContact CB-O 3.37Å; R360-V388 PolarHBondContact N-O 3.08Å; R360-V388 PolarHBondContact O-N 2.9Å; R360-R390 HydrophobicContact CG-CG 4.48Å
361L95.9Very high90.5Very high2 Ų256 Ų561%0.0133%0.333CS..EExtended strand (participates in β ladder)trans-91.7132.9174-65.1177.9000110.4V323 I341 V344 K345 I348 L368 L385 H386 L387V323-L361 HydrophobicContact CG1-CD2 4.05Å; I341-L361 HydrophobicContact CG2-CD1 4.18Å; V344-L361 HydrophobicContact CB-CD1 4.32Å; V344-L361 HydrophobicContact CG1-CD1 3.76Å; K345-L361 HydrophobicContact CG-CD1 3.95Å; K345-L361 HydrophobicContact CG-CG 4.47Å; I348-L361 HydrophobicContact CD1-CD1 4.02Å; I348-L361 HydrophobicContact CD1-CD2 3.71Å; I348-L361 HydrophobicContact CD1-CG 4.37Å; L361-L368 HydrophobicContact CB-CB 4.38Å; L361-L368 HydrophobicContact CB-CD1 4.04Å; L361-L368 HydrophobicContact CB-CG 4.4Å; L361-L368 PolarHBondContact O-N 3.38Å; L361-L385 HydrophobicContact CB-CD2 4.43Å; L361-L385 HydrophobicContact CD1-CD2 4.34Å; L361-H386 WeakPolarHBondContact CA-O 3.3Å; L361-L387 HydrophobicContact CD2-CB 4.23Å; L361-L387 HydrophobicContact CD2-CD1 3.97Å
362I96.8Very high90.8Very high46 Ų4655 Ų5524%0.23633%0.326CS..EExtended strand (participates in β ladder)trans-128130.8-179.1-56.5173.2000108.4K366 L385 H386 V388I362-K366 CarbonylContact C-O 3.57Å; I362-K366 VanDerWaalsContact CA-O 3.32Å; I362-K366 WeakPolarHBondContact CA-O 3.38Å; I362-L385 CarbonylContact O-C 3.58Å; I362-L385 WeakPolarHBondContact O-CA 3.12Å; I362-H386 HydrophobicContact CB-CB 4.33Å; I362-H386 PolarHBondContact N-O 3.03Å; I362-H386 PolarHBondContact O-N 2.85Å; I362-V388 HydrophobicContact CD1-CG2 3.74Å
363F97.6Very high91.1Very high42 Ų4253.1 Ų53.118%0.18432%0.32CS..EExtended strand (participates in β ladder)trans-131134.7172.8-177.1-115.1000109.5G365 K366 L368 I379 L385F363-G365 PolarHBondContact O-N 3.15Å; F363-G365 VanDerWaalsContact O-N 3.11Å; F363-K366 PolarHBondContact N-O 2.93Å; F363-K366 PolarHBondContact O-N 3.26Å; F363-L368 HydrophobicContact CB-CD1 4.1Å; F363-L368 HydrophobicContact CB-CD2 3.89Å; F363-L368 HydrophobicContact CB-CG 4.29Å; F363-I379 HydrophobicContact CB-CD1 4.25Å; F363-I379 HydrophobicContact CB-CG1 4.47Å; F363-I379 HydrophobicContact CD1-CD1 4.09Å; F363-I379 HydrophobicContact CD1-CG1 3.45Å; F363-I379 VanDerWaalsContact CD1-CG1 3.45Å; F363-I379 HydrophobicContact CD2-CG1 4.24Å; F363-I379 HydrophobicContact CE1-CB 4.49Å; F363-I379 HydrophobicContact CE1-CG1 3.57Å; F363-I379 HydrophobicContact CE2-CG1 4.36Å; F363-I379 HydrophobicContact CG-CD1 4.11Å; F363-I379 HydrophobicContact CG-CG1 3.8Å; F363-I379 HydrophobicContact CZ-CG1 4.04Å; F363-L385 HydrophobicContact CB-CG 4.23Å; F363-L385 HydrophobicContact CD2-CD1 3.85Å; F363-L385 HydrophobicContact CD2-CG 4.35Å; F363-L385 HydrophobicContact CE2-CD1 4.49Å; F363-L385 HydrophobicContact CG-CD1 4.41Å
364A94.1Very high91.6Very high95 Ų9550.2 Ų50.279%0.78529%0.29SS*.THydrogen-bonded Turntrans4840-178.500000114K366A364-K366 PolarHBondContact O-N 3.17Å
365G91.4Very high92.1Very high77 Ų7752 Ų5279%0.79431%0.305SS*.THydrogen-bonded Turntrans75.9-3.2-178.600000115.5F363F363-G365 PolarHBondContact O-N 3.15Å; F363-G365 VanDerWaalsContact O-N 3.11Å
366K94.4Very high92.7Very high106 Ų10655.4 Ų55.446%0.46132%0.322SS..EExtended strand (participates in β ladder)trans-102.1132.8178.5-170.1176.9177.9-176.90111I362 F363 A364 Y377I362-K366 CarbonylContact C-O 3.57Å; I362-K366 VanDerWaalsContact CA-O 3.32Å; I362-K366 WeakPolarHBondContact CA-O 3.38Å; F363-K366 PolarHBondContact N-O 2.93Å; F363-K366 PolarHBondContact O-N 3.26Å; A364-K366 PolarHBondContact O-N 3.17Å; K366-Y377 HydrophobicContact CD-CE1 4.12Å
367Q94.1Very high93.2Very high82 Ų8256.1 Ų56.138%0.38332%0.323SS..EExtended strand (participates in β ladder)trans-69.6133.6169.5-171.8-168.6-42.700109.7R360R360-Q367 HydrophobicContact CG-CG 4.17Å; R360-Q367 VanDerWaalsContact NE-CD 3.33Å; R360-Q367 VanDerWaalsContact NH2-OE1 3.15Å
368L96Very high93.9Very high4 Ų459.5 Ų59.52%0.02134%0.341CS..PPolyproline II helixtrans-83.1146.4179-53.6-175.8000111.3I341 L361 F363 Y377 I379 L385I341-L368 HydrophobicContact CD1-CB 3.95Å; I341-L368 HydrophobicContact CD1-CD1 3.58Å; I341-L368 HydrophobicContact CD1-CG 4.31Å; I341-L368 HydrophobicContact CG1-CB 3.89Å; I341-L368 HydrophobicContact CG1-CD1 4.46Å; I341-L368 HydrophobicContact CG2-CB 3.89Å; L361-L368 HydrophobicContact CB-CB 4.38Å; L361-L368 HydrophobicContact CB-CD1 4.04Å; L361-L368 HydrophobicContact CB-CG 4.4Å; L361-L368 PolarHBondContact O-N 3.38Å; F363-L368 HydrophobicContact CB-CD1 4.1Å; F363-L368 HydrophobicContact CB-CD2 3.89Å; F363-L368 HydrophobicContact CB-CG 4.29Å; L368-Y377 HydrophobicContact CB-CE2 4.19Å; L368-Y377 HydrophobicContact CD2-CD1 3.68Å; L368-Y377 HydrophobicContact CD2-CD2 3.74Å; L368-Y377 HydrophobicContact CD2-CE1 3.77Å; L368-Y377 HydrophobicContact CD2-CE2 3.79Å; L368-Y377 HydrophobicContact CD2-CG 3.66Å; L368-I379 HydrophobicContact CD1-CD1 3.84Å; L368-I379 HydrophobicContact CD2-CD1 4.47Å; L368-L385 HydrophobicContact CD1-CD2 3.57Å; L368-L385 HydrophobicContact CD1-CG 4.13Å
369E93.3Very high94.5Very high93 Ų9357.9 Ų57.944%0.43533%0.333SS..PPolyproline II helixtrans-102.7133.8-179.2-67.5161.7-151.300110.2I341 G371 R372 Y377I341-E369 WeakPolarHBondContact CB-O 2.88Å; I341-E369 VanDerWaalsContact CG1-O 3.28Å; I341-E369 WeakPolarHBondContact CG1-O 3.5Å; E369-G371 VanDerWaalsContact C-N 3.33Å; E369-G371 PolarHBondContact O-N 3.28Å; E369-R372 HydrophobicContact CB-CG 4.31Å; E369-R372 PolarHBondContact O-N 3.1Å; E369-R372 VanDerWaalsContact O-N 3.15Å; E369-R372 IonicContact OE1-NH2 3.17Å; E369-R372 IonicContact OE2-CZ 2.89Å; E369-R372 IonicContact OE2-NE 2.68Å; E369-R372 PolarHBondContact OE2-NE 3.27Å; E369-R372 IonicContact OE2-NH2 2.7Å; E369-R372 PolarHBondContact OE2-NH2 2.9Å; E369-Y377 WeakPolarHBondContact CB-OH 3.25Å; E369-Y377 WeakPolarHBondContact CG-OH 3.42Å; E369-Y377 PolarHBondContact N-OH 3.3Å
370D89.4Confident94.6Very high66 Ų6663.6 Ų63.635%0.35336%0.36SS..THydrogen-bonded Turntrans-57.3-39.5-169.1-69.2-8000113.8I341 E342 K345 R372I341-D370 PolarHBondContact N-O 2.93Å; E342-D370 HydrophobicContact CB-CB 4.27Å; E342-D370 PolarHBondContact N-O 3.09Å; E342-D370 VanDerWaalsContact N-O 3.15Å; K345-D370 WeakPolarHBondContact CE-OD1 3.31Å; K345-D370 VanDerWaalsContact NZ-CG 3.26Å; K345-D370 IonicContact NZ-OD1 2.89Å; K345-D370 PolarHBondContact NZ-OD1 2.94Å; K345-D370 IonicContact NZ-OD2 2.9Å; K345-D370 PolarHBondContact NZ-OD2 3.32Å; D370-R372 PolarHBondContact O-N 3.04Å
371G89.7Confident94.7Very high71 Ų7164.6 Ų64.673%0.73237%0.367SS*.THydrogen-bonded Turntrans-82.81.7-177.900000116.3E369E369-G371 VanDerWaalsContact C-N 3.33Å; E369-G371 PolarHBondContact O-N 3.28Å
372R95.3Very high94.6Very high100 Ų10070.6 Ų70.638%0.37740%0.395SS..SBendtrans-98.7158.6175.6-67.4-161.6-163.8-141.2-4.1111.2T340 I341 E369 D370 D376 Y377T340-R372 CarbonylContact C-O 3.55Å; T340-R372 VanDerWaalsContact CA-O 3.24Å; T340-R372 WeakPolarHBondContact CA-O 3.42Å; I341-R372 WeakPolarHBondContact CG1-O 3.33Å; I341-R372 PolarHBondContact N-O 3.04Å; E369-R372 HydrophobicContact CB-CG 4.31Å; E369-R372 PolarHBondContact O-N 3.1Å; E369-R372 VanDerWaalsContact O-N 3.15Å; E369-R372 IonicContact OE1-NH2 3.17Å; E369-R372 IonicContact OE2-CZ 2.89Å; E369-R372 IonicContact OE2-NE 2.68Å; E369-R372 PolarHBondContact OE2-NE 3.27Å; E369-R372 IonicContact OE2-NH2 2.7Å; E369-R372 PolarHBondContact OE2-NH2 2.9Å; D370-R372 PolarHBondContact O-N 3.04Å; R372-D376 HydrophobicContact CB-CB 4.22Å; R372-Y377 HydrophobicContact CB-CD2 4.31Å; R372-Y377 HydrophobicContact CB-CE2 3.6Å; R372-Y377 HydrophobicContact CG-CE2 4.31Å
373T96.5Very high94.6Very high27 Ų2769.4 Ų69.417%0.16639%0.391CS..BIsolated β-bridgetrans-91.8168.1178.470.60000113S338 D339 S375 D376 Y377S338-T373 WeakPolarHBondContact O-CG2 3.2Å; D339-T373 CarbonylContact O-C 3.58Å; D339-T373 WeakPolarHBondContact O-CA 3.41Å; T373-S375 VanDerWaalsContact C-N 3.27Å; T373-S375 PolarHBondContact O-N 2.9Å; T373-S375 PolarHBondContact OG1-N 3.48Å; T373-S375 PolarHBondContact OG1-OG 3.05Å; T373-D376 PolarHBondContact N-OD2 2.68Å; T373-D376 PolarHBondContact O-N 3.05Å; T373-D376 VanDerWaalsContact OG1-CG 3.27Å; T373-D376 PolarHBondContact OG1-N 3.1Å; T373-D376 PolarHBondContact OG1-OD2 3.25Å; T373-Y377 WeakPolarHBondContact O-CD2 3.47Å
374L96.3Very high94.6Very high0 Ų070.3 Ų70.30%040%0.4CS..THydrogen-bonded Turntrans-59.2-39.2169.6-69.1-178.4000112.1M319 I321 V335 D339 I341 V344 D376 Y377 N378 I379M319-L374 HydrophobicContact CE-CD1 4.35Å; I321-L374 HydrophobicContact CD1-CD1 4.19Å; I321-L374 HydrophobicContact CD1-CD2 4.28Å; V335-L374 HydrophobicContact CB-CD1 3.59Å; V335-L374 HydrophobicContact CG1-CD1 4.13Å; V335-L374 HydrophobicContact CG2-CD1 3.44Å; V335-L374 VanDerWaalsContact CG2-CD1 3.44Å; D339-L374 HydrophobicContact CB-CD1 4.27Å; D339-L374 HydrophobicContact CB-CG 4.49Å; D339-L374 PolarHBondContact O-N 2.83Å; I341-L374 HydrophobicContact CD1-CD2 3.96Å; V344-L374 HydrophobicContact CG2-CD1 4.09Å; V344-L374 HydrophobicContact CG2-CD2 4.01Å; V344-L374 HydrophobicContact CG2-CG 4.11Å; L374-D376 VanDerWaalsContact C-N 3.35Å; L374-D376 PolarHBondContact O-N 3.33Å; L374-Y377 PolarHBondContact O-N 2.96Å; L374-N378 PolarHBondContact O-N 2.9Å; L374-I379 HydrophobicContact CB-CB 4.25Å; L374-I379 HydrophobicContact CD2-CB 4.15Å; L374-I379 HydrophobicContact CD2-CD1 3.59Å; L374-I379 HydrophobicContact CD2-CG1 4.47Å; L374-I379 HydrophobicContact CD2-CG2 4.06Å; L374-I379 WeakPolarHBondContact O-CB 2.9Å; L374-I379 PolarHBondContact O-N 3.45Å
375S95.4Very high94.7Very high64 Ų6465.8 Ų65.845%0.44836%0.363SS..G310 helixtrans-64.8-35.4177.364.70000112.9P337 T373 Y377 N378P337-S375 WeakPolarHBondContact O-CB 3.25Å; P337-S375 PolarHBondContact O-N 2.92Å; P337-S375 PolarHBondContact O-OG 3.3Å; T373-S375 VanDerWaalsContact C-N 3.27Å; T373-S375 PolarHBondContact O-N 2.9Å; T373-S375 PolarHBondContact OG1-N 3.48Å; T373-S375 PolarHBondContact OG1-OG 3.05Å; S375-Y377 PolarHBondContact O-N 3.08Å; S375-N378 WeakPolarHBondContact O-CA 3.41Å; S375-N378 PolarHBondContact O-N 3.32Å
376D96.3Very high95Very high95 Ų9566.5 Ų66.551%0.50835%0.345SS..G310 helixtrans-60.4-30.2177.7-68.9-24.4000112.6R372 T373 L374R372-D376 HydrophobicContact CB-CB 4.22Å; T373-D376 PolarHBondContact N-OD2 2.68Å; T373-D376 PolarHBondContact O-N 3.05Å; T373-D376 VanDerWaalsContact OG1-CG 3.27Å; T373-D376 PolarHBondContact OG1-N 3.1Å; T373-D376 PolarHBondContact OG1-OD2 3.25Å; L374-D376 VanDerWaalsContact C-N 3.35Å; L374-D376 PolarHBondContact O-N 3.33Å
377Y96.7Very high95.1Very high29 Ų2961.6 Ų61.611%0.11432%0.324CS..G310 helixtrans-953.9175.5-69.6-73.8000113.4I341 K366 L368 E369 R372 T373 L374 S375 I379I341-Y377 HydrophobicContact CD1-CD2 4.39Å; I341-Y377 HydrophobicContact CD1-CE2 4.48Å; I341-Y377 HydrophobicContact CG1-CD2 4.49Å; I341-Y377 HydrophobicContact CG1-CE2 4.13Å; K366-Y377 HydrophobicContact CD-CE1 4.12Å; L368-Y377 HydrophobicContact CB-CE2 4.19Å; L368-Y377 HydrophobicContact CD2-CD1 3.68Å; L368-Y377 HydrophobicContact CD2-CD2 3.74Å; L368-Y377 HydrophobicContact CD2-CE1 3.77Å; L368-Y377 HydrophobicContact CD2-CE2 3.79Å; L368-Y377 HydrophobicContact CD2-CG 3.66Å; E369-Y377 WeakPolarHBondContact CB-OH 3.25Å; E369-Y377 WeakPolarHBondContact CG-OH 3.42Å; E369-Y377 PolarHBondContact N-OH 3.3Å; R372-Y377 HydrophobicContact CB-CD2 4.31Å; R372-Y377 HydrophobicContact CB-CE2 3.6Å; R372-Y377 HydrophobicContact CG-CE2 4.31Å; T373-Y377 WeakPolarHBondContact O-CD2 3.47Å; L374-Y377 PolarHBondContact O-N 2.96Å; S375-Y377 PolarHBondContact O-N 3.08Å; Y377-I379 PolarHBondContact O-N 2.94Å
378N95.9Very high95Very high110 Ų11059.6 Ų59.659%0.58832%0.318SS*.THydrogen-bonded Turntrans51.438.8-173.5-166.729.5000112.2L374 S375 Q380L374-N378 PolarHBondContact O-N 2.9Å; S375-N378 WeakPolarHBondContact O-CA 3.41Å; S375-N378 PolarHBondContact O-N 3.32Å; N378-Q380 PolarHBondContact O-N 2.9Å; N378-Q380 PolarHBondContact OD1-NE2 3.16Å
379I96.2Very high94.5Very high6 Ų663.3 Ų63.33%0.03134%0.337CS..  trans-75.5119.5172.8-66.3164.3000106.7M319 I321 F363 L368 L374 Y377 L385M319-I379 WeakPolarHBondContact CE-O 3.31Å; I321-I379 HydrophobicContact CG2-CG2 3.99Å; F363-I379 HydrophobicContact CB-CD1 4.25Å; F363-I379 HydrophobicContact CB-CG1 4.47Å; F363-I379 HydrophobicContact CD1-CD1 4.09Å; F363-I379 HydrophobicContact CD1-CG1 3.45Å; F363-I379 VanDerWaalsContact CD1-CG1 3.45Å; F363-I379 HydrophobicContact CD2-CG1 4.24Å; F363-I379 HydrophobicContact CE1-CB 4.49Å; F363-I379 HydrophobicContact CE1-CG1 3.57Å; F363-I379 HydrophobicContact CE2-CG1 4.36Å; F363-I379 HydrophobicContact CG-CD1 4.11Å; F363-I379 HydrophobicContact CG-CG1 3.8Å; F363-I379 HydrophobicContact CZ-CG1 4.04Å; L368-I379 HydrophobicContact CD1-CD1 3.84Å; L368-I379 HydrophobicContact CD2-CD1 4.47Å; L374-I379 HydrophobicContact CB-CB 4.25Å; L374-I379 HydrophobicContact CD2-CB 4.15Å; L374-I379 HydrophobicContact CD2-CD1 3.59Å; L374-I379 HydrophobicContact CD2-CG1 4.47Å; L374-I379 HydrophobicContact CD2-CG2 4.06Å; L374-I379 WeakPolarHBondContact O-CB 2.9Å; L374-I379 PolarHBondContact O-N 3.45Å; Y377-I379 PolarHBondContact O-N 2.94Å; I379-L385 HydrophobicContact CD1-CD1 4.17Å; I379-L385 HydrophobicContact CD1-CD2 4.4Å; I379-L385 HydrophobicContact CG1-CD1 4.49Å; I379-L385 HydrophobicContact CG2-CD1 3.91Å
380Q93.7Very high93.8Very high120 Ų12062.8 Ų62.856%0.56133%0.331SS*.  trans-105171.5-177.3-60.8-166.9-8.500111.5N378 E382 S383N378-Q380 PolarHBondContact O-N 2.9Å; N378-Q380 PolarHBondContact OD1-NE2 3.16Å; Q380-E382 PolarHBondContact O-N 3.49Å; Q380-S383 PolarHBondContact N-OG 2.86Å; Q380-S383 WeakPolarHBondContact O-CB 3.36Å; Q380-S383 PolarHBondContact O-N 3.12Å; Q380-S383 PolarHBondContact O-OG 2.88Å
381K93Very high92.5Very high121 Ų12167.2 Ų67.253%0.52635%0.354SS..THydrogen-bonded Turntrans-49.5138.2170.9-179170.3177.5170.80110.7M319 S383M319-K381 HydrophobicContact CG-CB 4.1Å; K381-S383 PolarHBondContact O-N 3.19Å
382E93.6Very high91Very high128 Ų12874.3 Ų74.360%0.59836%0.358SS*.THydrogen-bonded Turntrans669.2-177.4-65.6167.7-164.800115.6Q320 F322 Q380Q320-E382 PolarHBondContact O-N 2.96Å; F322-E382 WeakPolarHBondContact CD2-O 3.4Å; F322-E382 HydrophobicContact CE2-CB 3.89Å; F322-E382 HydrophobicContact CE2-CG 3.94Å; Q380-E382 PolarHBondContact O-N 3.49Å
383S97.2Very high89.3Confident21 Ų2171.6 Ų71.615%0.14736%0.362CS..  trans-61.2145.3171.6-67.30000111.8F322 Q380 K381F322-S383 PolarHBondContact N-O 2.91Å; Q380-S383 PolarHBondContact N-OG 2.86Å; Q380-S383 WeakPolarHBondContact O-CB 3.36Å; Q380-S383 PolarHBondContact O-N 3.12Å; Q380-S383 PolarHBondContact O-OG 2.88Å; K381-S383 PolarHBondContact O-N 3.19Å
384T97.3Very high87.9Confident61 Ų6170.3 Ų70.337%0.37435%0.354SS..EExtended strand (participates in β ladder)trans-107.5115.5176-57.70000111.1F322 K324F322-T384 HydrophobicContact CB-CG2 4.46Å; F322-T384 CarbonylContact O-C 3.59Å; F322-T384 VanDerWaalsContact O-CA 3.3Å; F322-T384 WeakPolarHBondContact O-CA 3.45Å; K324-T384 HydrophobicContact CB-CG2 4.03Å
385L97.7Very high87.4Confident0 Ų071.6 Ų71.60%036%0.36CS..EExtended strand (participates in β ladder)trans-90.7152.8168-79.263000109.2I321 F322 V323 K324 L361 I362 F363 L368 I379I321-L385 HydrophobicContact CD1-CD1 4.3Å; I321-L385 HydrophobicContact CD1-CD2 4.28Å; F322-L385 PolarHBondContact O-N 2.94Å; V323-L385 CarbonylContact C-O 3.5Å; V323-L385 WeakPolarHBondContact CA-O 3.24Å; V323-L385 HydrophobicContact CG2-CB 4.33Å; K324-L385 PolarHBondContact N-O 2.9Å; L361-L385 HydrophobicContact CB-CD2 4.43Å; L361-L385 HydrophobicContact CD1-CD2 4.34Å; I362-L385 CarbonylContact O-C 3.58Å; I362-L385 WeakPolarHBondContact O-CA 3.12Å; F363-L385 HydrophobicContact CB-CG 4.23Å; F363-L385 HydrophobicContact CD2-CD1 3.85Å; F363-L385 HydrophobicContact CD2-CG 4.35Å; F363-L385 HydrophobicContact CE2-CD1 4.49Å; F363-L385 HydrophobicContact CG-CD1 4.41Å; L368-L385 HydrophobicContact CD1-CD2 3.57Å; L368-L385 HydrophobicContact CD1-CG 4.13Å; I379-L385 HydrophobicContact CD1-CD1 4.17Å; I379-L385 HydrophobicContact CD1-CD2 4.4Å; I379-L385 HydrophobicContact CG1-CD1 4.49Å; I379-L385 HydrophobicContact CG2-CD1 3.91Å
386H97.6Very high87Confident92 Ų9270.8 Ų70.843%0.42635%0.349SS..EExtended strand (participates in β ladder)trans-106.3128.9172.5-67.773.5000109.7K324 L361 I362K324-H386 CarbonylContact O-C 3.59Å; K324-H386 WeakPolarHBondContact O-CA 3.44Å; L361-H386 WeakPolarHBondContact CA-O 3.3Å; I362-H386 HydrophobicContact CB-CB 4.33Å; I362-H386 PolarHBondContact N-O 3.03Å; I362-H386 PolarHBondContact O-N 2.85Å
387L95.3Very high86.9Confident3 Ų366.2 Ų66.22%0.01633%0.325CS..EExtended strand (participates in β ladder)trans-97.4117.4173.3176.262.2000109.9V323 K324 T325 I348 I354 Q359 L361 L389V323-L387 HydrophobicContact CG1-CB 3.53Å; V323-L387 HydrophobicContact CG1-CD2 4.43Å; K324-L387 PolarHBondContact O-N 3.5Å; T325-L387 HydrophobicContact CG2-CD2 4.34Å; I348-L387 HydrophobicContact CG2-CD2 4.07Å; I354-L387 HydrophobicContact CD1-CD2 4.12Å; Q359-L387 HydrophobicContact CB-CD1 3.71Å; Q359-L387 HydrophobicContact CG-CD1 3.93Å; L361-L387 HydrophobicContact CD2-CB 4.23Å; L361-L387 HydrophobicContact CD2-CD1 3.97Å; L387-L389 HydrophobicContact CD1-CD2 4.18Å; L387-L389 HydrophobicContact CD2-CD2 4.08Å; L387-L389 HydrophobicContact CG-CD2 4.02Å
388V91.8Very high86.9Confident41 Ų4167.2 Ų67.225%0.24833%0.33CS..EExtended strand (participates in β ladder)trans-109.7123.8171177.90000108.2L326 R360 I362L326-V388 HydrophobicContact CD1-CG1 4.18Å; L326-V388 HydrophobicContact CD1-CG2 4.38Å; L326-V388 HydrophobicContact CD2-CG2 4.25Å; L326-V388 HydrophobicContact CG-CG2 4.38Å; R360-V388 WeakPolarHBondContact CA-O 3.26Å; R360-V388 HydrophobicContact CB-CB 4.12Å; R360-V388 WeakPolarHBondContact CB-O 3.37Å; R360-V388 PolarHBondContact N-O 3.08Å; R360-V388 PolarHBondContact O-N 2.9Å; I362-V388 HydrophobicContact CD1-CG2 3.74Å
389L87.2Confident87Confident82 Ų8262 Ų6243%0.42930%0.302SS..EExtended strand (participates in β ladder)trans-82.5129.3178.3-58.3-178.4000110.5I354 Q358 L387I354-L389 HydrophobicContact CD1-CD2 4.05Å; I354-L389 HydrophobicContact CG2-CD2 3.65Å; Q358-L389 CarbonylContact O-C 3.59Å; Q358-L389 WeakPolarHBondContact O-CA 3.41Å; L387-L389 HydrophobicContact CD1-CD2 4.18Å; L387-L389 HydrophobicContact CD2-CD2 4.08Å; L387-L389 HydrophobicContact CG-CD2 4.02Å
390R78Confident86.9Confident81 Ų8166 Ų6631%0.30632%0.319SS..  trans-84.7114.7168.3-66.1-177.8-179.5150.4-1.8108.4Q358 R360 R392Q358-R390 PolarHBondContact O-N 2.88Å; R360-R390 HydrophobicContact CG-CG 4.48Å; R390-R392 VanDerWaalsContact C-N 3.27Å; R390-R392 PolarHBondContact O-N 2.85Å
391L62.3Low86.8Confident160 Ų16061.5 Ų61.584%0.83830%0.3SS*.THydrogen-bonded Turntrans-70.7-12.4-174.8-69.2170.1000115.1
392R57.6Low86.4Confident219 Ų21962.4 Ų62.483%0.82631%0.31SS*.THydrogen-bonded Turntrans-148.820.1-173.6-64-170.8-173.8169.52.6115.3R390R390-R392 VanDerWaalsContact C-N 3.27Å; R390-R392 PolarHBondContact O-N 2.85Å
393G59.1Low85.9Confident43 Ų4362.4 Ų62.444%0.44332%0.319SS..  trans-81.9-27.7-170.200000115.2
394G67.9Low85.3Confident1 Ų164 Ų641%0.0134%0.338CS..SBendtrans-74.5165.2-166.800000115.6D357 Q396 K457D357-G394 WeakPolarHBondContact OD2-CA 3.42Å; G394-Q396 PolarHBondContact O-N 2.87Å; G394-Q396 VanDerWaalsContact O-N 3.17Å; G394-K457 WeakPolarHBondContact O-CE 3.1Å; G394-K457 PolarHBondContact O-NZ 2.72Å
395M85.6Confident85Confident27 Ų2765.9 Ų65.913%0.13334%0.341CS..EExtended strand (participates in β ladder)trans-75.599.8169.1171.8172.516400107.8I397 V411 P413 L450 I455 K457M395-I397 HydrophobicContact CE-CG2 4.15Å; M395-V411 WeakPolarHBondContact CB-O 3.44Å; M395-V411 HydrophobicContact CE-CG2 4.25Å; M395-V411 HydrophobicContact CG-CG2 4.07Å; M395-V411 VanDerWaalsContact O-CG2 3.31Å; M395-V411 WeakPolarHBondContact O-CG2 3.44Å; M395-V411 PolarHBondContact O-N 3.18Å; M395-V411 VanDerWaalsContact O-O 3.05Å; M395-P413 HydrophobicContact SD-CB 4.47Å; M395-P413 HydrophobicContact SD-CG 3.74Å; M395-L450 HydrophobicContact CE-CD1 4.25Å; M395-I455 HydrophobicContact CE-CG2 4.4Å; M395-I455 WeakPolarHBondContact CE-O 3.35Å; M395-K457 HydrophobicContact CG-CB 4.23Å
396Q87.7Confident84.7Confident46 Ų4668.9 Ų68.922%0.21536%0.36CS..EExtended strand (participates in β ladder)trans-86.7141.5172.2-70.7179.89.900109.9G394 T408 L409 E410 E458G394-Q396 PolarHBondContact O-N 2.87Å; G394-Q396 VanDerWaalsContact O-N 3.17Å; Q396-T408 HydrophobicContact CB-CG2 4.27Å; Q396-T408 HydrophobicContact CG-CG2 4.28Å; Q396-L409 CarbonylContact C-O 3.55Å; Q396-L409 VanDerWaalsContact CA-O 3.25Å; Q396-L409 WeakPolarHBondContact CA-O 3.41Å; Q396-E410 HydrophobicContact CG-CG 4.37Å; Q396-E410 VanDerWaalsContact CG-OE1 3.31Å; Q396-E410 WeakPolarHBondContact CG-OE1 3.47Å; Q396-E410 WeakPolarHBondContact CG-OE2 3.27Å; Q396-E410 PolarHBondContact NE2-OE1 2.99Å; Q396-E458 WeakPolarHBondContact O-CA 3.46Å; Q396-E458 PolarHBondContact O-N 3.47Å
397I94.6Very high84.3Confident0 Ų064.8 Ų64.80%034%0.341CS..EExtended strand (participates in β ladder)trans-124.7159.9164.363.9171.7000109.1M395 L409 V411 V420 L450 I455 S459 L461M395-I397 HydrophobicContact CE-CG2 4.15Å; I397-L409 HydrophobicContact CG1-CB 4.02Å; I397-L409 PolarHBondContact N-O 2.93Å; I397-L409 PolarHBondContact O-N 2.79Å; I397-V411 HydrophobicContact CB-CG2 4.31Å; I397-V411 HydrophobicContact CD1-CG1 3.89Å; I397-V411 HydrophobicContact CD1-CG2 3.98Å; I397-V411 HydrophobicContact CG1-CG1 3.97Å; I397-V411 HydrophobicContact CG1-CG2 3.78Å; I397-V411 HydrophobicContact CG2-CG2 3.74Å; I397-V420 HydrophobicContact CD1-CG1 4.22Å; I397-L450 HydrophobicContact CD1-CD1 4.2Å; I397-L450 HydrophobicContact CD1-CD2 4.32Å; I397-I455 HydrophobicContact CG2-CG2 3.89Å; I397-S459 WeakPolarHBondContact CA-O 3.34Å; I397-L461 HydrophobicContact CB-CD1 4.43Å; I397-L461 HydrophobicContact CD1-CD1 4.04Å; I397-L461 HydrophobicContact CD1-CD2 4.28Å
398F96Very high84.2Confident50 Ų5067.1 Ų67.122%0.21936%0.356CS..EExtended strand (participates in β ladder)trans-111.7138.4177.9-56.2-71.7000109.9T406 I407 T408 E458 S459 T460 L461F398-T406 HydrophobicContact CB-CG2 3.89Å; F398-T406 HydrophobicContact CD1-CG2 4.08Å; F398-T406 HydrophobicContact CG-CG2 4.31Å; F398-I407 CarbonylContact C-O 3.59Å; F398-I407 WeakPolarHBondContact CA-O 3.46Å; F398-T408 HydrophobicContact CD1-CG2 4.11Å; F398-T408 HydrophobicContact CE1-CG2 3.83Å; F398-E458 WeakPolarHBondContact CD2-O 3.38Å; F398-E458 HydrophobicContact CE2-CB 3.86Å; F398-E458 HydrophobicContact CE2-CG 3.97Å; F398-E458 HydrophobicContact CZ-CG 4.45Å; F398-S459 PolarHBondContact N-O 3.05Å; F398-T460 HydrophobicContact CB-CG2 4.38Å; F398-T460 CarbonylContact O-C 3.58Å; F398-T460 VanDerWaalsContact O-CA 3.3Å; F398-T460 WeakPolarHBondContact O-CA 3.42Å; F398-L461 PolarHBondContact O-N 2.91Å
399V97.1Very high84.1Confident0 Ų065.2 Ų65.20%034%0.344CS..EExtended strand (participates in β ladder)trans-118112.1174.1-178.30000108.1I407 L409 I424 L437 L461 L463V399-I407 HydrophobicContact CB-CB 4.31Å; V399-I407 PolarHBondContact N-O 2.83Å; V399-I407 PolarHBondContact O-N 3.22Å; V399-L409 HydrophobicContact CG2-CD1 3.59Å; V399-L409 HydrophobicContact CG2-CG 4.24Å; V399-I424 HydrophobicContact CG1-CD1 4.15Å; V399-I424 HydrophobicContact CG2-CD1 4.18Å; V399-L437 HydrophobicContact CG1-CD2 3.92Å; V399-L461 CarbonylContact C-O 3.57Å; V399-L461 WeakPolarHBondContact CA-O 3.37Å; V399-L461 HydrophobicContact CG2-CB 4.37Å; V399-L463 HydrophobicContact CG1-CB 3.51Å; V399-L463 HydrophobicContact CG1-CD2 4.37Å
400K95.7Very high84Confident89 Ų8963.2 Ų63.239%0.38733%0.332SS..EExtended strand (participates in β ladder)trans-93.8126.7176.6-82.4-173178.5-179.50110.9K405 T406 T460 L461 H462 L463K400-K405 WeakPolarHBondContact CA-O 3.32Å; K400-T406 WeakPolarHBondContact CE-OG1 3.44Å; K400-T406 HydrophobicContact CG-CG2 4.13Å; K400-T406 WeakPolarHBondContact CG-OG1 3.45Å; K400-T460 HydrophobicContact CB-CG2 4.28Å; K400-T460 HydrophobicContact CD-CG2 3.95Å; K400-T460 HydrophobicContact CG-CG2 3.93Å; K400-L461 PolarHBondContact N-O 2.92Å; K400-H462 CarbonylContact O-C 3.47Å; K400-H462 WeakPolarHBondContact O-CA 3.44Å; K400-L463 PolarHBondContact O-N 3.07Å
401T91.2Very high84.6Confident26 Ų2659.5 Ų59.516%0.1632%0.319CS..EExtended strand (participates in β ladder)trans-80.4163.5170.768.30000110.6T403 G404 K405 I407 L463T401-T403 PolarHBondContact O-N 3.46Å; T401-T403 PolarHBondContact OG1-N 2.99Å; T401-T403 PolarHBondContact OG1-OG1 3.04Å; T401-G404 PolarHBondContact O-N 3.05Å; T401-K405 HydrophobicContact CG2-CB 4.34Å; T401-K405 PolarHBondContact N-O 2.83Å; T401-K405 WeakPolarHBondContact OG1-CB 3.26Å; T401-K405 PolarHBondContact OG1-N 3.3Å; T401-K405 PolarHBondContact OG1-O 3.32Å; T401-I407 HydrophobicContact CG2-CD1 4.06Å; T401-L463 HydrophobicContact CG2-CD2 4.37Å
402L83.5Confident85.7Confident141 Ų14154.8 Ų54.874%0.73829%0.292SS*.THydrogen-bonded Turntrans-61.7-20.6170.9-66.8175.9000113.5G404 V464L402-G404 PolarHBondContact O-N 2.83Å; L402-V464 HydrophobicContact CD1-CG1 4.22Å; L402-V464 HydrophobicContact CD1-CG2 4.29Å; L402-V464 HydrophobicContact CD2-CG2 4.36Å; L402-V464 HydrophobicContact CG-CG2 4.36Å
403T84.2Confident87.3Confident128 Ų12847.6 Ų47.679%0.78527%0.274SS*.THydrogen-bonded Turntrans-79.4-3.7174.960.70000113T401 K405T401-T403 PolarHBondContact O-N 3.46Å; T401-T403 PolarHBondContact OG1-N 2.99Å; T401-T403 PolarHBondContact OG1-OG1 3.04Å; T403-K405 VanDerWaalsContact C-N 3.33Å
404G83.4Confident88.8Confident53 Ų5349 Ų4955%0.54628%0.277SS..SBendtrans86.6-3.7-177.400000114.4T401 L402 T406T401-G404 PolarHBondContact O-N 3.05Å; L402-G404 PolarHBondContact O-N 2.83Å; G404-T406 PolarHBondContact O-N 3.33Å
405K90.6Very high90Very high101 Ų10149.7 Ų49.744%0.43928%0.281SS..  trans-64.8132.5173.9-174.8179.3174.9-174.60109.2K400 T401 T403 E428K400-K405 WeakPolarHBondContact CA-O 3.32Å; T401-K405 HydrophobicContact CG2-CB 4.34Å; T401-K405 PolarHBondContact N-O 2.83Å; T401-K405 WeakPolarHBondContact OG1-CB 3.26Å; T401-K405 PolarHBondContact OG1-N 3.3Å; T401-K405 PolarHBondContact OG1-O 3.32Å; T403-K405 VanDerWaalsContact C-N 3.33Å; K405-E428 WeakPolarHBondContact CE-OE1 3.49Å; K405-E428 IonicContact NZ-OE1 2.68Å; K405-E428 PolarHBondContact NZ-OE1 3.43Å; K405-E428 IonicContact NZ-OE2 3.47Å; K405-E428 PolarHBondContact NZ-OE2 3.35Å
406T91.7Very high90.5Very high63 Ų6350.2 Ų50.239%0.38729%0.285SS..EExtended strand (participates in β ladder)trans-107.9123.7175.4-54.60000109.1F398 K400 G404F398-T406 HydrophobicContact CB-CG2 3.89Å; F398-T406 HydrophobicContact CD1-CG2 4.08Å; F398-T406 HydrophobicContact CG-CG2 4.31Å; K400-T406 WeakPolarHBondContact CE-OG1 3.44Å; K400-T406 HydrophobicContact CG-CG2 4.13Å; K400-T406 WeakPolarHBondContact CG-OG1 3.45Å; G404-T406 PolarHBondContact O-N 3.33Å
407I90.9Very high91Very high6 Ų648 Ų483%0.03128%0.275CS..EExtended strand (participates in β ladder)trans-104.8125.3177.5-54.9151.5000107.3F398 V399 T401 L409 K427 E428F398-I407 CarbonylContact C-O 3.59Å; F398-I407 WeakPolarHBondContact CA-O 3.46Å; V399-I407 HydrophobicContact CB-CB 4.31Å; V399-I407 PolarHBondContact N-O 2.83Å; V399-I407 PolarHBondContact O-N 3.22Å; T401-I407 HydrophobicContact CG2-CD1 4.06Å; I407-L409 HydrophobicContact CG2-CD2 4.04Å; I407-L409 HydrophobicContact CG2-CG 4.42Å; I407-K427 HydrophobicContact CG2-CD 4.23Å; I407-E428 HydrophobicContact CD1-CG 3.66Å; I407-E428 HydrophobicContact CG1-CG 4.04Å; I407-E428 HydrophobicContact CG2-CG 4.43Å
408T91.5Very high91.1Very high53 Ų5353.2 Ų53.233%0.32530%0.299SS..EExtended strand (participates in β ladder)trans-91.4127.1174.7-51.40000109.6Q396 F398 K427Q396-T408 HydrophobicContact CB-CG2 4.27Å; Q396-T408 HydrophobicContact CG-CG2 4.28Å; F398-T408 HydrophobicContact CD1-CG2 4.11Å; F398-T408 HydrophobicContact CE1-CG2 3.83Å; T408-K427 PolarHBondContact O-NZ 3.15Å
409L89.8Confident91Very high1 Ų154.2 Ų54.21%0.00531%0.307CS..EExtended strand (participates in β ladder)trans-117.2139.6176.4-60.6177.7000110.4Q396 I397 V399 I407 V411 V420 K423 I424 K427Q396-L409 CarbonylContact C-O 3.55Å; Q396-L409 VanDerWaalsContact CA-O 3.25Å; Q396-L409 WeakPolarHBondContact CA-O 3.41Å; I397-L409 HydrophobicContact CG1-CB 4.02Å; I397-L409 PolarHBondContact N-O 2.93Å; I397-L409 PolarHBondContact O-N 2.79Å; V399-L409 HydrophobicContact CG2-CD1 3.59Å; V399-L409 HydrophobicContact CG2-CG 4.24Å; I407-L409 HydrophobicContact CG2-CD2 4.04Å; I407-L409 HydrophobicContact CG2-CG 4.42Å; L409-V411 HydrophobicContact CB-CG1 4.05Å; L409-V420 HydrophobicContact CD1-CG1 3.73Å; L409-K423 HydrophobicContact CD2-CB 4.24Å; L409-I424 HydrophobicContact CD1-CD1 4.12Å; L409-I424 HydrophobicContact CD1-CG1 3.59Å; L409-I424 HydrophobicContact CD2-CG1 4.42Å; L409-K427 HydrophobicContact CD2-CD 3.91Å
410E85.9Confident90.9Very high40 Ų4054.2 Ų54.219%0.18731%0.307CS..EExtended strand (participates in β ladder)trans-94.2123.3168-64.1-77.9-175.300107.6Q358 Q396 K423Q358-E410 PolarHBondContact NE2-OE1 3.26Å; Q396-E410 HydrophobicContact CG-CG 4.37Å; Q396-E410 VanDerWaalsContact CG-OE1 3.31Å; Q396-E410 WeakPolarHBondContact CG-OE1 3.47Å; Q396-E410 WeakPolarHBondContact CG-OE2 3.27Å; Q396-E410 PolarHBondContact NE2-OE1 2.99Å; E410-K423 PolarHBondContact O-NZ 3.28Å
411V89.3Confident90.9Very high3 Ų350.6 Ų50.62%0.01829%0.291CS..EExtended strand (participates in β ladder)trans-140.7161.3-170.8-63.30000110.9M395 I397 L409 D415 V420 K423 L450M395-V411 WeakPolarHBondContact CB-O 3.44Å; M395-V411 HydrophobicContact CE-CG2 4.25Å; M395-V411 HydrophobicContact CG-CG2 4.07Å; M395-V411 VanDerWaalsContact O-CG2 3.31Å; M395-V411 WeakPolarHBondContact O-CG2 3.44Å; M395-V411 PolarHBondContact O-N 3.18Å; M395-V411 VanDerWaalsContact O-O 3.05Å; I397-V411 HydrophobicContact CB-CG2 4.31Å; I397-V411 HydrophobicContact CD1-CG1 3.89Å; I397-V411 HydrophobicContact CD1-CG2 3.98Å; I397-V411 HydrophobicContact CG1-CG1 3.97Å; I397-V411 HydrophobicContact CG1-CG2 3.78Å; I397-V411 HydrophobicContact CG2-CG2 3.74Å; L409-V411 HydrophobicContact CB-CG1 4.05Å; V411-D415 WeakPolarHBondContact CA-OD2 3.41Å; V411-V420 HydrophobicContact CG1-CG2 4.18Å; V411-K423 HydrophobicContact CG1-CD 4.12Å; V411-L450 HydrophobicContact CB-CD1 3.57Å; V411-L450 HydrophobicContact CG1-CD1 4.13Å; V411-L450 HydrophobicContact CG2-CD1 3.38Å
412E87.1Confident90.9Very high60 Ų6052 Ų5228%0.2830%0.299SS..  trans-107151.6169.1-64.8-173.517700110.8S414 D415E412-S414 PolarHBondContact O-N 2.93Å; E412-S414 VanDerWaalsContact O-N 3.09Å; E412-D415 PolarHBondContact N-OD2 3.41Å; E412-D415 VanDerWaalsContact O-CB 3.32Å; E412-D415 WeakPolarHBondContact O-CB 3.44Å; E412-D415 PolarHBondContact O-N 3.17Å
413P90.9Very high91.4Very high68 Ų6847.7 Ų47.744%0.44228%0.275SS..THydrogen-bonded Turntrans-56.7-27.1176.3-23.231.5000113.9M395 S451M395-P413 HydrophobicContact SD-CB 4.47Å; M395-P413 HydrophobicContact SD-CG 3.74Å; P413-S451 WeakPolarHBondContact O-CB 3.32Å; P413-S451 PolarHBondContact O-N 3.12Å; P413-S451 PolarHBondContact O-OG 3.41Å; P413-S451 VanDerWaalsContact O-OG 3.1Å
414S91.1Very high91.8Very high72 Ų7241.6 Ų41.650%0.50324%0.237SC..THydrogen-bonded Turntrans-79.6-14.1176.741.90000113.8E412 T416 T449E412-S414 PolarHBondContact O-N 2.93Å; E412-S414 VanDerWaalsContact O-N 3.09Å; S414-T416 PolarHBondContact O-N 2.8Å; S414-T449 WeakPolarHBondContact O-CG2 3.42Å
415D92Very high92.2Very high17 Ų1741.3 Ų41.39%0.09122%0.222CC..  trans-59.1131179.2-86.5-33.4000110.1V411 E412 N419 V420 K423 T449 L450V411-D415 WeakPolarHBondContact CA-OD2 3.41Å; E412-D415 PolarHBondContact N-OD2 3.41Å; E412-D415 VanDerWaalsContact O-CB 3.32Å; E412-D415 WeakPolarHBondContact O-CB 3.44Å; E412-D415 PolarHBondContact O-N 3.17Å; D415-N419 HydrophobicContact CB-CB 4.3Å; D415-N419 PolarHBondContact OD1-ND2 3.16Å; D415-V420 HydrophobicContact CB-CG2 4.33Å; D415-K423 VanDerWaalsContact OD2-CE 3.25Å; D415-K423 WeakPolarHBondContact OD2-CE 3.43Å; D415-K423 IonicContact OD2-NZ 3.32Å; D415-K423 PolarHBondContact OD2-NZ 2.9Å; D415-T449 CarbonylContact O-C 3.59Å; D415-T449 WeakPolarHBondContact O-CA 3.21Å; D415-L450 HydrophobicContact CB-CD1 4.34Å; D415-L450 PolarHBondContact O-N 3.38Å
416T97Very high91.9Very high37 Ų3742.4 Ų42.423%0.22723%0.233CC..BIsolated β-bridgetrans-71.7157.8171.164.10000110.5S414 E418 N419 V420 R448S414-T416 PolarHBondContact O-N 2.8Å; T416-E418 PolarHBondContact O-N 3.01Å; T416-N419 WeakPolarHBondContact O-CB 3.42Å; T416-N419 PolarHBondContact O-N 3.31Å; T416-N419 VanDerWaalsContact O-N 3.08Å; T416-N419 PolarHBondContact OG1-N 2.9Å; T416-N419 VanDerWaalsContact OG1-N 3.13Å; T416-N419 PolarHBondContact OG1-OD1 2.89Å; T416-N419 VanDerWaalsContact OG1-OD1 3.09Å; T416-V420 WeakPolarHBondContact O-CG2 3.38Å; T416-V420 PolarHBondContact O-N 2.75Å; T416-R448 CarbonylContact C-O 3.59Å; T416-R448 WeakPolarHBondContact CA-O 3.17Å
417I97.7Very high91.6Very high0 Ų045.3 Ų45.30%024%0.24CC..Hα-helixtrans-61.6-32.2174.4-59.1-54.4000110.9V420 K421 L437 L444 E445 D446 R448 L450 Y453I417-V420 PolarHBondContact O-N 3.02Å; I417-K421 WeakPolarHBondContact O-CG 3.27Å; I417-K421 PolarHBondContact O-N 2.72Å; I417-L437 HydrophobicContact CG2-CD1 4.14Å; I417-L444 HydrophobicContact CD1-CB 4.03Å; I417-L444 HydrophobicContact CD1-CD1 3.65Å; I417-L444 HydrophobicContact CD1-CG 4.39Å; I417-L444 HydrophobicContact CG1-CB 3.93Å; I417-L444 HydrophobicContact CG1-CD1 4.48Å; I417-L444 HydrophobicContact CG2-CB 3.86Å; I417-E445 WeakPolarHBondContact CB-O 3.24Å; I417-E445 VanDerWaalsContact CG1-O 3.28Å; I417-E445 WeakPolarHBondContact CG1-O 3.29Å; I417-D446 PolarHBondContact N-O 2.75Å; I417-R448 WeakPolarHBondContact CG1-O 3.39Å; I417-R448 PolarHBondContact N-O 2.62Å; I417-L450 HydrophobicContact CD1-CD2 3.9Å; I417-Y453 HydrophobicContact CD1-CD2 4.32Å; I417-Y453 HydrophobicContact CD1-CE2 4.46Å; I417-Y453 HydrophobicContact CG1-CD2 4.47Å; I417-Y453 HydrophobicContact CG1-CE2 4.14Å
418E96.2Very high91.6Very high110 Ų11048.1 Ų48.151%0.51425%0.253SS..Hα-helixtrans-59.6-47.6170.1-168.4168-169.100112.1T416 V420 K421 T422 D446T416-E418 PolarHBondContact O-N 3.01Å; E418-V420 VanDerWaalsContact C-N 3.29Å; E418-V420 PolarHBondContact O-N 2.78Å; E418-K421 WeakPolarHBondContact O-CB 3.4Å; E418-K421 PolarHBondContact O-N 2.83Å; E418-T422 PolarHBondContact O-N 3.24Å; E418-T422 PolarHBondContact O-OG1 2.73Å; E418-D446 HydrophobicContact CB-CB 4.28Å; E418-D446 PolarHBondContact N-O 3.32Å; E418-D446 VanDerWaalsContact N-O 3.09Å
419N93.4Very high91.3Very high71 Ų7148.5 Ų48.538%0.3827%0.267SS..Hα-helixtrans-57.5-42.7174.9-66.2-2000111.6D415 T416 K421 T422 K423D415-N419 HydrophobicContact CB-CB 4.3Å; D415-N419 PolarHBondContact OD1-ND2 3.16Å; T416-N419 WeakPolarHBondContact O-CB 3.42Å; T416-N419 PolarHBondContact O-N 3.31Å; T416-N419 VanDerWaalsContact O-N 3.08Å; T416-N419 PolarHBondContact OG1-N 2.9Å; T416-N419 VanDerWaalsContact OG1-N 3.13Å; T416-N419 PolarHBondContact OG1-OD1 2.89Å; T416-N419 VanDerWaalsContact OG1-OD1 3.09Å; N419-K421 VanDerWaalsContact C-N 3.31Å; N419-K421 PolarHBondContact O-N 3.11Å; N419-T422 PolarHBondContact O-N 3.22Å; N419-K423 WeakPolarHBondContact O-CG 3.49Å; N419-K423 PolarHBondContact O-N 3.41Å
420V95.7Very high91.2Very high0 Ų049.7 Ų49.70%027%0.273CS..Hα-helixtrans-63.1-39.6177.9179.60000111I397 L409 V411 D415 T416 I417 E418 K423 I424 L437 L450I397-V420 HydrophobicContact CD1-CG1 4.22Å; L409-V420 HydrophobicContact CD1-CG1 3.73Å; V411-V420 HydrophobicContact CG1-CG2 4.18Å; D415-V420 HydrophobicContact CB-CG2 4.33Å; T416-V420 WeakPolarHBondContact O-CG2 3.38Å; T416-V420 PolarHBondContact O-N 2.75Å; I417-V420 PolarHBondContact O-N 3.02Å; E418-V420 VanDerWaalsContact C-N 3.29Å; E418-V420 PolarHBondContact O-N 2.78Å; V420-K423 PolarHBondContact O-N 3.15Å; V420-I424 HydrophobicContact CG1-CD1 4.31Å; V420-I424 WeakPolarHBondContact O-CG1 3.17Å; V420-I424 PolarHBondContact O-N 3.17Å; V420-L437 HydrophobicContact CB-CD1 4.31Å; V420-L437 HydrophobicContact CG1-CD1 3.84Å; V420-L450 HydrophobicContact CG2-CD1 4.13Å; V420-L450 HydrophobicContact CG2-CD2 4.04Å; V420-L450 HydrophobicContact CG2-CG 4.18Å
421K95.5Very high91.2Very high12 Ų1248.6 Ų48.65%0.05227%0.27CS..Hα-helixtrans-65.1-40.5175.5-71.3171.4163.1-166.70112.3I417 E418 N419 K423 I424 Q425 P432 Q435 L437 D446I417-K421 WeakPolarHBondContact O-CG 3.27Å; I417-K421 PolarHBondContact O-N 2.72Å; E418-K421 WeakPolarHBondContact O-CB 3.4Å; E418-K421 PolarHBondContact O-N 2.83Å; N419-K421 VanDerWaalsContact C-N 3.31Å; N419-K421 PolarHBondContact O-N 3.11Å; K421-K423 VanDerWaalsContact C-N 3.35Å; K421-I424 WeakPolarHBondContact O-CB 3.23Å; K421-I424 PolarHBondContact O-N 3.16Å; K421-I424 VanDerWaalsContact O-N 3.14Å; K421-Q425 PolarHBondContact O-N 2.77Å; K421-P432 HydrophobicContact CB-CB 3.78Å; K421-P432 HydrophobicContact CB-CG 4.32Å; K421-P432 HydrophobicContact CD-CB 4.23Å; K421-P432 WeakPolarHBondContact CD-O 3.13Å; K421-P432 PolarHBondContact NZ-O 2.85Å; K421-Q435 HydrophobicContact CD-CB 4.33Å; K421-Q435 WeakPolarHBondContact CE-O 3.46Å; K421-Q435 HydrophobicContact CG-CB 4.05Å; K421-Q435 PolarHBondContact NZ-O 2.92Å; K421-Q435 VanDerWaalsContact NZ-O 3.13Å; K421-Q435 PolarHBondContact O-NE2 2.81Å; K421-Q435 PolarHBondContact O-OE1 3.08Å; K421-L437 HydrophobicContact CG-CD1 4Å; K421-D446 WeakPolarHBondContact CE-OD1 3.19Å; K421-D446 VanDerWaalsContact NZ-CG 3.31Å; K421-D446 IonicContact NZ-OD1 3.87Å; K421-D446 PolarHBondContact NZ-OD1 3.02Å; K421-D446 IonicContact NZ-OD2 3.16Å; K421-D446 PolarHBondContact NZ-OD2 2.89Å; K421-D446 VanDerWaalsContact NZ-OD2 3.15Å
422T92.4Very high91.2Very high55 Ų5549.5 Ų49.534%0.33728%0.276SS..Hα-helixtrans-60.4-44.7172.7-53.40000110.9E418 N419 I424 Q425 D426E418-T422 PolarHBondContact O-N 3.24Å; E418-T422 PolarHBondContact O-OG1 2.73Å; N419-T422 PolarHBondContact O-N 3.22Å; T422-I424 PolarHBondContact O-N 3.35Å; T422-Q425 CarbonylContact O-C 3.54Å; T422-Q425 WeakPolarHBondContact O-CA 3.4Å; T422-Q425 VanDerWaalsContact O-CB 3.3Å; T422-Q425 WeakPolarHBondContact O-CB 3.33Å; T422-Q425 PolarHBondContact O-N 2.92Å; T422-D426 VanDerWaalsContact O-CG 3.3Å; T422-D426 PolarHBondContact O-N 2.7Å
423K92.3Very high91.2Very high51 Ų5149 Ų4922%0.22228%0.275CS..Hα-helixtrans-60-31.4174.8-68.9170.3-173.2-104.10113L409 E410 V411 D415 N419 V420 K421 K427L409-K423 HydrophobicContact CD2-CB 4.24Å; E410-K423 PolarHBondContact O-NZ 3.28Å; V411-K423 HydrophobicContact CG1-CD 4.12Å; D415-K423 VanDerWaalsContact OD2-CE 3.25Å; D415-K423 WeakPolarHBondContact OD2-CE 3.43Å; D415-K423 IonicContact OD2-NZ 3.32Å; D415-K423 PolarHBondContact OD2-NZ 2.9Å; N419-K423 WeakPolarHBondContact O-CG 3.49Å; N419-K423 PolarHBondContact O-N 3.41Å; V420-K423 PolarHBondContact O-N 3.15Å; K421-K423 VanDerWaalsContact C-N 3.35Å; K423-K427 PolarHBondContact O-N 3.46Å
424I93.6Very high91.1Very high0 Ų047.9 Ų47.90%026%0.264CS..Hα-helixtrans-72.6-41.9172.7-65.4163.2000110.6V399 L409 V420 K421 T422 D426 K427 E428 Q435 L437 L463V399-I424 HydrophobicContact CG1-CD1 4.15Å; V399-I424 HydrophobicContact CG2-CD1 4.18Å; L409-I424 HydrophobicContact CD1-CD1 4.12Å; L409-I424 HydrophobicContact CD1-CG1 3.59Å; L409-I424 HydrophobicContact CD2-CG1 4.42Å; V420-I424 HydrophobicContact CG1-CD1 4.31Å; V420-I424 WeakPolarHBondContact O-CG1 3.17Å; V420-I424 PolarHBondContact O-N 3.17Å; K421-I424 WeakPolarHBondContact O-CB 3.23Å; K421-I424 PolarHBondContact O-N 3.16Å; K421-I424 VanDerWaalsContact O-N 3.14Å; T422-I424 PolarHBondContact O-N 3.35Å; I424-D426 VanDerWaalsContact C-N 3.31Å; I424-D426 PolarHBondContact O-N 2.91Å; I424-K427 PolarHBondContact O-N 3.1Å; I424-E428 HydrophobicContact CG2-CB 4.44Å; I424-E428 WeakPolarHBondContact O-CB 3.36Å; I424-E428 PolarHBondContact O-N 2.85Å; I424-Q435 VanDerWaalsContact CD1-OE1 3.28Å; I424-L437 HydrophobicContact CD1-CD1 4.06Å; I424-L437 HydrophobicContact CD1-CD2 3.78Å; I424-L437 HydrophobicContact CD1-CG 4.37Å; I424-L463 HydrophobicContact CG2-CD2 4.08Å
425Q91.2Very high91.2Very high48 Ų4844.5 Ų44.522%0.22424%0.24CC..Hα-helixtrans-57.7-46.3174.6-176.2-17921.700110.7K421 T422 K427 E428 G429 I430 P432 E488K421-Q425 PolarHBondContact O-N 2.77Å; T422-Q425 CarbonylContact O-C 3.54Å; T422-Q425 WeakPolarHBondContact O-CA 3.4Å; T422-Q425 VanDerWaalsContact O-CB 3.3Å; T422-Q425 WeakPolarHBondContact O-CB 3.33Å; T422-Q425 PolarHBondContact O-N 2.92Å; Q425-K427 VanDerWaalsContact C-N 3.27Å; Q425-K427 PolarHBondContact O-N 2.96Å; Q425-E428 PolarHBondContact O-N 2.73Å; Q425-G429 WeakPolarHBondContact O-CA 3.4Å; Q425-G429 PolarHBondContact O-N 3.32Å; Q425-I430 VanDerWaalsContact CA-O 3.3Å; Q425-I430 WeakPolarHBondContact CA-O 3.08Å; Q425-I430 VanDerWaalsContact CB-O 3.24Å; Q425-I430 WeakPolarHBondContact CB-O 3.33Å; Q425-P432 HydrophobicContact CB-CG 4.49Å; Q425-P432 VanDerWaalsContact OE1-CD 3.28Å; Q425-E488 PolarHBondContact NE2-OE2 3.39Å
426D84.4Confident91.3Very high124 Ų12447.8 Ų47.866%0.66325%0.251SS*.Hα-helixtrans-61.6-36.2179.5-64.3-26.8000112.4T422 I424T422-D426 VanDerWaalsContact O-CG 3.3Å; T422-D426 PolarHBondContact O-N 2.7Å; I424-D426 VanDerWaalsContact C-N 3.31Å; I424-D426 PolarHBondContact O-N 2.91Å
427K86.3Confident91.2Very high124 Ų12446 Ų4654%0.53924%0.24SC..Hα-helixtrans-85.3-34.4-179.1-76.3-158.8178.1-163.50114.6I407 T408 L409 K423 I424 Q425I407-K427 HydrophobicContact CG2-CD 4.23Å; T408-K427 PolarHBondContact O-NZ 3.15Å; L409-K427 HydrophobicContact CD2-CD 3.91Å; K423-K427 PolarHBondContact O-N 3.46Å; I424-K427 PolarHBondContact O-N 3.1Å; Q425-K427 VanDerWaalsContact C-N 3.27Å; Q425-K427 PolarHBondContact O-N 2.96Å
428E90.3Very high91.2Very high65 Ų6548.3 Ų48.330%0.30425%0.252SS..Hα-helixtrans-123.3-5.7-166.6-63.1-71.614300113.5K405 I407 I424 Q425 I430K405-E428 WeakPolarHBondContact CE-OE1 3.49Å; K405-E428 IonicContact NZ-OE1 2.68Å; K405-E428 PolarHBondContact NZ-OE1 3.43Å; K405-E428 IonicContact NZ-OE2 3.47Å; K405-E428 PolarHBondContact NZ-OE2 3.35Å; I407-E428 HydrophobicContact CD1-CG 3.66Å; I407-E428 HydrophobicContact CG1-CG 4.04Å; I407-E428 HydrophobicContact CG2-CG 4.43Å; I424-E428 HydrophobicContact CG2-CB 4.44Å; I424-E428 WeakPolarHBondContact O-CB 3.36Å; I424-E428 PolarHBondContact O-N 2.85Å; Q425-E428 PolarHBondContact O-N 2.73Å; E428-I430 VanDerWaalsContact C-N 3.26Å; E428-I430 HydrophobicContact CB-CD1 3.97Å; E428-I430 HydrophobicContact CB-CG1 3.98Å; E428-I430 PolarHBondContact O-N 2.9Å
429G85.2Confident91.3Very high60 Ų6044.9 Ų44.962%0.61924%0.236SC*.  trans72.113.8-179.200000114.5Q425 P431Q425-G429 WeakPolarHBondContact O-CA 3.4Å; Q425-G429 PolarHBondContact O-N 3.32Å; G429-P431 WeakPolarHBondContact O-CD 3.45Å
430I86.9Confident91.4Very high27 Ų2745.8 Ų45.814%0.13825%0.253CS..  trans-92.8117.7-174.8-54.6175.9000109.5Q425 E428 Q434 Q435 L463 L465Q425-I430 VanDerWaalsContact CA-O 3.3Å; Q425-I430 WeakPolarHBondContact CA-O 3.08Å; Q425-I430 VanDerWaalsContact CB-O 3.24Å; Q425-I430 WeakPolarHBondContact CB-O 3.33Å; E428-I430 VanDerWaalsContact C-N 3.26Å; E428-I430 HydrophobicContact CB-CD1 3.97Å; E428-I430 HydrophobicContact CB-CG1 3.98Å; E428-I430 PolarHBondContact O-N 2.9Å; I430-Q434 HydrophobicContact CG2-CB 4.4Å; I430-Q435 HydrophobicContact CB-CG 4.45Å; I430-Q435 HydrophobicContact CG2-CG 3.75Å; I430-Q435 PolarHBondContact O-NE2 2.91Å; I430-L463 HydrophobicContact CD1-CD2 4.24Å; I430-L465 HydrophobicContact CD1-CD1 4.39Å; I430-L465 HydrophobicContact CD1-CD2 3.98Å; I430-L465 HydrophobicContact CG2-CD2 3.65Å
431P86.6Confident91.2Very high17 Ų1749.4 Ų49.411%0.1129%0.29CS..  trans-59.4139.8180-28.838.4000113.7G429 D433 Q434 Q435G429-P431 WeakPolarHBondContact O-CD 3.45Å; P431-D433 VanDerWaalsContact C-N 3.27Å; P431-D433 WeakPolarHBondContact CB-OD1 3.48Å; P431-D433 PolarHBondContact O-N 3.1Å; P431-Q434 HydrophobicContact CB-CG 4.39Å; P431-Q434 WeakPolarHBondContact O-CB 3.43Å; P431-Q434 PolarHBondContact O-N 2.88Å; P431-Q435 WeakPolarHBondContact O-CG 3.27Å; P431-Q435 PolarHBondContact O-N 2.82Å
432P90.3Very high91.2Very high22 Ų2255.6 Ų55.614%0.14332%0.317CS..G310 helixtrans-55.6-32.7-176.1-31.137.8000115.7K421 Q425 Q434 Q435K421-P432 HydrophobicContact CB-CB 3.78Å; K421-P432 HydrophobicContact CB-CG 4.32Å; K421-P432 HydrophobicContact CD-CB 4.23Å; K421-P432 WeakPolarHBondContact CD-O 3.13Å; K421-P432 PolarHBondContact NZ-O 2.85Å; Q425-P432 HydrophobicContact CB-CG 4.49Å; Q425-P432 VanDerWaalsContact OE1-CD 3.28Å; P432-Q434 VanDerWaalsContact C-N 3.3Å; P432-Q434 PolarHBondContact O-N 3.39Å; P432-Q435 WeakPolarHBondContact O-CB 3.33Å; P432-Q435 PolarHBondContact O-N 3.31Å; P432-Q435 VanDerWaalsContact O-N 3.14Å
433D86.8Confident91.3Very high50 Ų5057.9 Ų57.927%0.26732%0.324SS..G310 helixtrans-70.8-24.9178.663.1-13.1000113.3P431 Q435 G470P431-D433 VanDerWaalsContact C-N 3.27Å; P431-D433 WeakPolarHBondContact CB-OD1 3.48Å; P431-D433 PolarHBondContact O-N 3.1Å; D433-Q435 VanDerWaalsContact C-N 3.32Å; D433-G470 WeakPolarHBondContact OD2-CA 3.5Å; D433-G470 PolarHBondContact OD2-N 3Å
434Q88.3Confident91.6Very high43 Ų4355.6 Ų55.620%0.20131%0.314CS..G310 helixtrans-82.6-11.9171.9-63.2-178.39.900112.3I430 P431 P432 L465 R466I430-Q434 HydrophobicContact CG2-CB 4.4Å; P431-Q434 HydrophobicContact CB-CG 4.39Å; P431-Q434 WeakPolarHBondContact O-CB 3.43Å; P431-Q434 PolarHBondContact O-N 2.88Å; P432-Q434 VanDerWaalsContact C-N 3.3Å; P432-Q434 PolarHBondContact O-N 3.39Å; Q434-L465 CarbonylContact O-C 3.6Å; Q434-L465 WeakPolarHBondContact O-CA 3.33Å; Q434-R466 PolarHBondContact O-N 3.49Å
435Q92.8Very high91.7Very high1 Ų160.6 Ų60.61%0.00534%0.337CS..EExtended strand (participates in β ladder)trans-91.1128.7-177.9-59.6177.536.100111.8K421 I424 I430 P431 P432 D433 L463K421-Q435 HydrophobicContact CD-CB 4.33Å; K421-Q435 WeakPolarHBondContact CE-O 3.46Å; K421-Q435 HydrophobicContact CG-CB 4.05Å; K421-Q435 PolarHBondContact NZ-O 2.92Å; K421-Q435 VanDerWaalsContact NZ-O 3.13Å; K421-Q435 PolarHBondContact O-NE2 2.81Å; K421-Q435 PolarHBondContact O-OE1 3.08Å; I424-Q435 VanDerWaalsContact CD1-OE1 3.28Å; I430-Q435 HydrophobicContact CB-CG 4.45Å; I430-Q435 HydrophobicContact CG2-CG 3.75Å; I430-Q435 PolarHBondContact O-NE2 2.91Å; P431-Q435 WeakPolarHBondContact O-CG 3.27Å; P431-Q435 PolarHBondContact O-N 2.82Å; P432-Q435 WeakPolarHBondContact O-CB 3.33Å; P432-Q435 PolarHBondContact O-N 3.31Å; P432-Q435 VanDerWaalsContact O-N 3.14Å; D433-Q435 VanDerWaalsContact C-N 3.32Å; Q435-L463 HydrophobicContact CB-CD1 3.71Å; Q435-L463 HydrophobicContact CG-CD1 3.96Å
436R93.7Very high91.8Very high86 Ų8661.5 Ų61.533%0.32534%0.344SS..EExtended strand (participates in β ladder)trans-114.2118.4159.4-74.2-175.3179.9-1800109.6L463 V464 R466R436-L463 WeakPolarHBondContact O-CA 3.44Å; R436-V464 HydrophobicContact CB-CB 4.31Å; R436-V464 WeakPolarHBondContact CB-O 3.5Å; R436-V464 PolarHBondContact N-O 3.32Å; R436-V464 PolarHBondContact O-N 3.43Å; R436-R466 HydrophobicContact CG-CG 3.82Å
437L96.6Very high92.3Very high1 Ų159 Ų591%0.00535%0.348CS..EExtended strand (participates in β ladder)trans-94.6136.9172.2-68.3172.8000110.3V399 I417 V420 K421 I424 L444 L461 H462 L463V399-L437 HydrophobicContact CG1-CD2 3.92Å; I417-L437 HydrophobicContact CG2-CD1 4.14Å; V420-L437 HydrophobicContact CB-CD1 4.31Å; V420-L437 HydrophobicContact CG1-CD1 3.84Å; K421-L437 HydrophobicContact CG-CD1 4Å; I424-L437 HydrophobicContact CD1-CD1 4.06Å; I424-L437 HydrophobicContact CD1-CD2 3.78Å; I424-L437 HydrophobicContact CD1-CG 4.37Å; L437-L444 HydrophobicContact CB-CB 4.27Å; L437-L444 HydrophobicContact CB-CD1 3.94Å; L437-L444 HydrophobicContact CB-CG 4.29Å; L437-L444 PolarHBondContact O-N 3.02Å; L437-L461 HydrophobicContact CB-CD2 4.4Å; L437-L461 HydrophobicContact CD1-CD2 4.31Å; L437-L461 HydrophobicContact CD2-CB 4.49Å; L437-L461 HydrophobicContact CD2-CD2 4.4Å; L437-H462 CarbonylContact C-O 3.5Å; L437-H462 WeakPolarHBondContact CA-O 3.33Å; L437-L463 HydrophobicContact CD2-CB 4.25Å; L437-L463 HydrophobicContact CD2-CD1 4.09Å
438I97.3Very high92.8Very high48 Ų4858.2 Ų58.225%0.24634%0.341CS..EExtended strand (participates in β ladder)trans-129.4131.3-179-58.4162.7000108.3K442 L461 H462 V464I438-K442 CarbonylContact C-O 3.58Å; I438-K442 VanDerWaalsContact CA-O 3.27Å; I438-K442 WeakPolarHBondContact CA-O 3.4Å; I438-K442 WeakPolarHBondContact CG2-O 3.26Å; I438-L461 CarbonylContact O-C 3.6Å; I438-L461 WeakPolarHBondContact O-CA 3.49Å; I438-H462 HydrophobicContact CB-CB 4.32Å; I438-H462 PolarHBondContact N-O 3.48Å; I438-H462 PolarHBondContact O-N 3.14Å; I438-V464 HydrophobicContact CD1-CB 4.48Å; I438-V464 HydrophobicContact CD1-CG2 3.68Å
439F97.7Very high93.1Very high38 Ų3856.4 Ų56.417%0.16734%0.335CS..EExtended strand (participates in β ladder)trans-136.8135.7174.1-176.1-111.8000109.8G441 K442 L444 I455 L461F439-G441 PolarHBondContact O-N 2.68Å; F439-G441 VanDerWaalsContact O-N 3.11Å; F439-K442 PolarHBondContact N-O 2.93Å; F439-K442 PolarHBondContact O-N 3.17Å; F439-L444 HydrophobicContact CB-CD1 4.11Å; F439-L444 HydrophobicContact CB-CD2 3.91Å; F439-L444 HydrophobicContact CB-CG 4.3Å; F439-I455 HydrophobicContact CB-CD1 4.23Å; F439-I455 HydrophobicContact CB-CG1 4.46Å; F439-I455 HydrophobicContact CD1-CD1 4.07Å; F439-I455 HydrophobicContact CD1-CG1 3.44Å; F439-I455 VanDerWaalsContact CD1-CG1 3.44Å; F439-I455 HydrophobicContact CD2-CG1 4.24Å; F439-I455 HydrophobicContact CE1-CB 4.47Å; F439-I455 HydrophobicContact CE1-CG1 3.56Å; F439-I455 HydrophobicContact CE2-CG1 4.37Å; F439-I455 HydrophobicContact CG-CD1 4.09Å; F439-I455 HydrophobicContact CG-CG1 3.79Å; F439-I455 HydrophobicContact CZ-CG1 4.04Å; F439-L461 HydrophobicContact CB-CG 4.28Å; F439-L461 HydrophobicContact CD2-CD1 4.11Å; F439-L461 HydrophobicContact CD2-CG 4.29Å
440A94.5Very high93.6Very high90 Ų9053.6 Ų53.674%0.74431%0.305SS*.THydrogen-bonded Turntrans48.240.4-178.800000113.9K442A440-K442 PolarHBondContact O-N 3.3Å
441G91.8Very high94Very high76 Ų7655.3 Ų55.378%0.78432%0.32SS*.THydrogen-bonded Turntrans74.5-0.8-178.900000115.5F439F439-G441 PolarHBondContact O-N 2.68Å; F439-G441 VanDerWaalsContact O-N 3.11Å
442K95.4Very high94.5Very high141 Ų14159 Ų5961%0.61334%0.339SS*.EExtended strand (participates in β ladder)trans-101.5135.3177.1-64.9-176.6180178.90110.7I438 F439 A440I438-K442 CarbonylContact C-O 3.58Å; I438-K442 VanDerWaalsContact CA-O 3.27Å; I438-K442 WeakPolarHBondContact CA-O 3.4Å; I438-K442 WeakPolarHBondContact CG2-O 3.26Å; F439-K442 PolarHBondContact N-O 2.93Å; F439-K442 PolarHBondContact O-N 3.17Å; A440-K442 PolarHBondContact O-N 3.3Å
443Q95.7Very high94.9Very high103 Ų10359.7 Ų59.748%0.48134%0.339SS..EExtended strand (participates in β ladder)trans-71.1132.6166.2-174.2-177.4-37.100108.7
444L97.4Very high95.3Very high4 Ų462.5 Ų62.52%0.02135%0.353CS..PPolyproline II helixtrans-83.2140.4-179.5-55.1-173000110.8I417 L437 F439 Y453 I455 L461I417-L444 HydrophobicContact CD1-CB 4.03Å; I417-L444 HydrophobicContact CD1-CD1 3.65Å; I417-L444 HydrophobicContact CD1-CG 4.39Å; I417-L444 HydrophobicContact CG1-CB 3.93Å; I417-L444 HydrophobicContact CG1-CD1 4.48Å; I417-L444 HydrophobicContact CG2-CB 3.86Å; L437-L444 HydrophobicContact CB-CB 4.27Å; L437-L444 HydrophobicContact CB-CD1 3.94Å; L437-L444 HydrophobicContact CB-CG 4.29Å; L437-L444 PolarHBondContact O-N 3.02Å; F439-L444 HydrophobicContact CB-CD1 4.11Å; F439-L444 HydrophobicContact CB-CD2 3.91Å; F439-L444 HydrophobicContact CB-CG 4.3Å; L444-Y453 HydrophobicContact CB-CE2 4.24Å; L444-Y453 HydrophobicContact CD2-CD1 3.65Å; L444-Y453 HydrophobicContact CD2-CD2 3.69Å; L444-Y453 HydrophobicContact CD2-CE1 3.79Å; L444-Y453 HydrophobicContact CD2-CE2 3.8Å; L444-Y453 HydrophobicContact CD2-CG 3.61Å; L444-I455 HydrophobicContact CD1-CD1 3.82Å; L444-L461 HydrophobicContact CD1-CD2 3.6Å; L444-L461 HydrophobicContact CD1-CG 4.27Å
445E96.4Very high95.7Very high104 Ų10460.7 Ų60.749%0.48635%0.345SS..PPolyproline II helixtrans-97.5133.5-179.9-65.9170.4-174.800110.8I417 G447 R448 Y453I417-E445 WeakPolarHBondContact CB-O 3.24Å; I417-E445 VanDerWaalsContact CG1-O 3.28Å; I417-E445 WeakPolarHBondContact CG1-O 3.29Å; E445-G447 VanDerWaalsContact C-N 3.33Å; E445-G447 PolarHBondContact O-N 3.2Å; E445-R448 HydrophobicContact CB-CG 4.28Å; E445-R448 PolarHBondContact O-N 3.34Å; E445-R448 VanDerWaalsContact O-N 3.13Å; E445-R448 IonicContact OE1-NH2 2.78Å; E445-R448 IonicContact OE2-CZ 2.9Å; E445-R448 IonicContact OE2-NE 2.9Å; E445-R448 PolarHBondContact OE2-NE 3.14Å; E445-R448 IonicContact OE2-NH2 2.6Å; E445-R448 PolarHBondContact OE2-NH2 2.74Å; E445-R448 VanDerWaalsContact OE2-NH2 3.16Å; E445-Y453 WeakPolarHBondContact CB-OH 3.4Å; E445-Y453 PolarHBondContact N-OH 2.97Å
446D93.8Very high95.7Very high67 Ų6766.1 Ų66.136%0.35837%0.371SS..THydrogen-bonded Turntrans-56.4-39.9-169.5-68.6-4.6000114.1I417 E418 K421 R448I417-D446 PolarHBondContact N-O 2.75Å; E418-D446 HydrophobicContact CB-CB 4.28Å; E418-D446 PolarHBondContact N-O 3.32Å; E418-D446 VanDerWaalsContact N-O 3.09Å; K421-D446 WeakPolarHBondContact CE-OD1 3.19Å; K421-D446 VanDerWaalsContact NZ-CG 3.31Å; K421-D446 IonicContact NZ-OD1 3.87Å; K421-D446 PolarHBondContact NZ-OD1 3.02Å; K421-D446 IonicContact NZ-OD2 3.16Å; K421-D446 PolarHBondContact NZ-OD2 2.89Å; K421-D446 VanDerWaalsContact NZ-OD2 3.15Å; D446-R448 VanDerWaalsContact C-N 3.34Å; D446-R448 PolarHBondContact O-N 2.85Å
447G93.5Very high95.5Very high72 Ų7266.8 Ų66.874%0.74238%0.376SS*.THydrogen-bonded Turntrans-82.2-0-17800000116.2E445E445-G447 VanDerWaalsContact C-N 3.33Å; E445-G447 PolarHBondContact O-N 3.2Å
448R97.2Very high95.3Very high108 Ų10872.8 Ų72.841%0.40840%0.404SS..SBendtrans-96.1160.2176.3-67.9-155.4-159-156.7-1.3111.4T416 I417 E445 D446 D452 Y453T416-R448 CarbonylContact C-O 3.59Å; T416-R448 WeakPolarHBondContact CA-O 3.17Å; I417-R448 WeakPolarHBondContact CG1-O 3.39Å; I417-R448 PolarHBondContact N-O 2.62Å; E445-R448 HydrophobicContact CB-CG 4.28Å; E445-R448 PolarHBondContact O-N 3.34Å; E445-R448 VanDerWaalsContact O-N 3.13Å; E445-R448 IonicContact OE1-NH2 2.78Å; E445-R448 IonicContact OE2-CZ 2.9Å; E445-R448 IonicContact OE2-NE 2.9Å; E445-R448 PolarHBondContact OE2-NE 3.14Å; E445-R448 IonicContact OE2-NH2 2.6Å; E445-R448 PolarHBondContact OE2-NH2 2.74Å; E445-R448 VanDerWaalsContact OE2-NH2 3.16Å; D446-R448 VanDerWaalsContact C-N 3.34Å; D446-R448 PolarHBondContact O-N 2.85Å; R448-D452 WeakPolarHBondContact CA-OD2 3.07Å; R448-D452 HydrophobicContact CB-CB 4.19Å; R448-D452 WeakPolarHBondContact CB-OD2 3.29Å; R448-Y453 HydrophobicContact CB-CD2 4.34Å; R448-Y453 HydrophobicContact CB-CE2 3.57Å; R448-Y453 WeakPolarHBondContact CD-OH 3.21Å; R448-Y453 HydrophobicContact CG-CE2 4.27Å
449T97Very high95.3Very high27 Ų2771.5 Ų71.517%0.16640%0.399CS..BIsolated β-bridgetrans-92169.8178.267.20000112.8S414 D415 S451 D452 Y453S414-T449 WeakPolarHBondContact O-CG2 3.42Å; D415-T449 CarbonylContact O-C 3.59Å; D415-T449 WeakPolarHBondContact O-CA 3.21Å; T449-S451 VanDerWaalsContact C-N 3.29Å; T449-S451 PolarHBondContact O-N 3.25Å; T449-S451 PolarHBondContact OG1-N 2.99Å; T449-S451 PolarHBondContact OG1-OG 3.22Å; T449-D452 PolarHBondContact N-OD2 3.45Å; T449-D452 PolarHBondContact O-N 2.71Å; T449-D452 VanDerWaalsContact OG1-CG 3.24Å; T449-D452 PolarHBondContact OG1-N 2.96Å; T449-D452 VanDerWaalsContact OG1-N 3.09Å; T449-D452 PolarHBondContact OG1-OD2 3.06Å; T449-Y453 WeakPolarHBondContact O-CD2 3.39Å
450L96.2Very high95.2Very high0 Ų072.1 Ų72.10%041%0.406CS..THydrogen-bonded Turntrans-60.8-38.6168.1-68.1-176.9000112.2M395 I397 V411 D415 I417 V420 Y453 N454 I455M395-L450 HydrophobicContact CE-CD1 4.25Å; I397-L450 HydrophobicContact CD1-CD1 4.2Å; I397-L450 HydrophobicContact CD1-CD2 4.32Å; V411-L450 HydrophobicContact CB-CD1 3.57Å; V411-L450 HydrophobicContact CG1-CD1 4.13Å; V411-L450 HydrophobicContact CG2-CD1 3.38Å; D415-L450 HydrophobicContact CB-CD1 4.34Å; D415-L450 PolarHBondContact O-N 3.38Å; I417-L450 HydrophobicContact CD1-CD2 3.9Å; V420-L450 HydrophobicContact CG2-CD1 4.13Å; V420-L450 HydrophobicContact CG2-CD2 4.04Å; V420-L450 HydrophobicContact CG2-CG 4.18Å; L450-Y453 PolarHBondContact O-N 3.28Å; L450-N454 PolarHBondContact O-N 3.31Å; L450-I455 HydrophobicContact CB-CB 4.19Å; L450-I455 HydrophobicContact CD2-CB 4.15Å; L450-I455 HydrophobicContact CD2-CD1 3.57Å; L450-I455 HydrophobicContact CD2-CG1 4.45Å; L450-I455 HydrophobicContact CD2-CG2 4.07Å; L450-I455 WeakPolarHBondContact O-CB 3.42Å; L450-I455 PolarHBondContact O-N 2.92Å
451S95.6Very high95.4Very high64 Ų6467.8 Ų67.845%0.44837%0.371SS..G310 helixtrans-65.4-35.2177.657.60000113.2P413 T449 Y453 N454P413-S451 WeakPolarHBondContact O-CB 3.32Å; P413-S451 PolarHBondContact O-N 3.12Å; P413-S451 PolarHBondContact O-OG 3.41Å; P413-S451 VanDerWaalsContact O-OG 3.1Å; T449-S451 VanDerWaalsContact C-N 3.29Å; T449-S451 PolarHBondContact O-N 3.25Å; T449-S451 PolarHBondContact OG1-N 2.99Å; T449-S451 PolarHBondContact OG1-OG 3.22Å; S451-Y453 PolarHBondContact O-N 3.35Å; S451-N454 PolarHBondContact O-N 3.33Å
452D97Very high95.6Very high94 Ų9468.7 Ų68.750%0.50335%0.354SS..G310 helixtrans-58.8-32.3176.1-71.5-28.6000112.8R448 T449R448-D452 WeakPolarHBondContact CA-OD2 3.07Å; R448-D452 HydrophobicContact CB-CB 4.19Å; R448-D452 WeakPolarHBondContact CB-OD2 3.29Å; T449-D452 PolarHBondContact N-OD2 3.45Å; T449-D452 PolarHBondContact O-N 2.71Å; T449-D452 VanDerWaalsContact OG1-CG 3.24Å; T449-D452 PolarHBondContact OG1-N 2.96Å; T449-D452 VanDerWaalsContact OG1-N 3.09Å; T449-D452 PolarHBondContact OG1-OD2 3.06Å
453Y97.2Very high95.7Very high37 Ų3762.1 Ų62.115%0.14533%0.325CS..G310 helixtrans-94.73.9176.7-68.7-73.3000113.5I417 L444 E445 R448 T449 L450 S451 I455I417-Y453 HydrophobicContact CD1-CD2 4.32Å; I417-Y453 HydrophobicContact CD1-CE2 4.46Å; I417-Y453 HydrophobicContact CG1-CD2 4.47Å; I417-Y453 HydrophobicContact CG1-CE2 4.14Å; L444-Y453 HydrophobicContact CB-CE2 4.24Å; L444-Y453 HydrophobicContact CD2-CD1 3.65Å; L444-Y453 HydrophobicContact CD2-CD2 3.69Å; L444-Y453 HydrophobicContact CD2-CE1 3.79Å; L444-Y453 HydrophobicContact CD2-CE2 3.8Å; L444-Y453 HydrophobicContact CD2-CG 3.61Å; E445-Y453 WeakPolarHBondContact CB-OH 3.4Å; E445-Y453 PolarHBondContact N-OH 2.97Å; R448-Y453 HydrophobicContact CB-CD2 4.34Å; R448-Y453 HydrophobicContact CB-CE2 3.57Å; R448-Y453 WeakPolarHBondContact CD-OH 3.21Å; R448-Y453 HydrophobicContact CG-CE2 4.27Å; T449-Y453 WeakPolarHBondContact O-CD2 3.39Å; L450-Y453 PolarHBondContact O-N 3.28Å; S451-Y453 PolarHBondContact O-N 3.35Å; Y453-I455 PolarHBondContact O-N 2.98Å
454N96.2Very high95.5Very high108 Ų10859.1 Ų59.158%0.57831%0.314SS*.THydrogen-bonded Turntrans51.840.4-173.2-168.631.5000112L450 S451 Q456L450-N454 PolarHBondContact O-N 3.31Å; S451-N454 PolarHBondContact O-N 3.33Å; N454-Q456 PolarHBondContact O-N 3.1Å; N454-Q456 PolarHBondContact OD1-NE2 3.5Å
455I96Very high95.1Very high6 Ų663.3 Ų63.33%0.03134%0.336CS..  trans-76.2121.6171.8-66166.7000106.7M395 I397 F439 L444 L450 Y453 L461M395-I455 HydrophobicContact CE-CG2 4.4Å; M395-I455 WeakPolarHBondContact CE-O 3.35Å; I397-I455 HydrophobicContact CG2-CG2 3.89Å; F439-I455 HydrophobicContact CB-CD1 4.23Å; F439-I455 HydrophobicContact CB-CG1 4.46Å; F439-I455 HydrophobicContact CD1-CD1 4.07Å; F439-I455 HydrophobicContact CD1-CG1 3.44Å; F439-I455 VanDerWaalsContact CD1-CG1 3.44Å; F439-I455 HydrophobicContact CD2-CG1 4.24Å; F439-I455 HydrophobicContact CE1-CB 4.47Å; F439-I455 HydrophobicContact CE1-CG1 3.56Å; F439-I455 HydrophobicContact CE2-CG1 4.37Å; F439-I455 HydrophobicContact CG-CD1 4.09Å; F439-I455 HydrophobicContact CG-CG1 3.79Å; F439-I455 HydrophobicContact CZ-CG1 4.04Å; L444-I455 HydrophobicContact CD1-CD1 3.82Å; L450-I455 HydrophobicContact CB-CB 4.19Å; L450-I455 HydrophobicContact CD2-CB 4.15Å; L450-I455 HydrophobicContact CD2-CD1 3.57Å; L450-I455 HydrophobicContact CD2-CG1 4.45Å; L450-I455 HydrophobicContact CD2-CG2 4.07Å; L450-I455 WeakPolarHBondContact O-CB 3.42Å; L450-I455 PolarHBondContact O-N 2.92Å; Y453-I455 PolarHBondContact O-N 2.98Å; I455-L461 HydrophobicContact CD1-CD1 4.29Å; I455-L461 HydrophobicContact CD1-CD2 4.25Å; I455-L461 HydrophobicContact CD1-CG 4.42Å; I455-L461 HydrophobicContact CG2-CD1 3.97Å
456Q93.2Very high94.4Very high115 Ų11562.9 Ų62.954%0.53733%0.33SS..  trans-110.5172.7-176.3-60.7-171.9-3.700111.2N454 E458 S459N454-Q456 PolarHBondContact O-N 3.1Å; N454-Q456 PolarHBondContact OD1-NE2 3.5Å; Q456-E458 PolarHBondContact O-N 3.33Å; Q456-S459 PolarHBondContact N-OG 3.39Å; Q456-S459 WeakPolarHBondContact O-CB 3.36Å; Q456-S459 PolarHBondContact O-N 3.27Å; Q456-S459 PolarHBondContact O-OG 3.31Å
457K90.5Very high93.3Very high100 Ų10067.5 Ų67.544%0.43535%0.354SS..THydrogen-bonded Turntrans-50136.7171.7-177.8164.4179.31530110.7G394 M395 S459G394-K457 WeakPolarHBondContact O-CE 3.1Å; G394-K457 PolarHBondContact O-NZ 2.72Å; M395-K457 HydrophobicContact CG-CB 4.23Å; K457-S459 PolarHBondContact O-N 3.47Å
458E91.9Very high92Very high127 Ų12773.2 Ų73.259%0.59335%0.353SS*.THydrogen-bonded Turntrans6510.3-176.4-64.6174.8-171.900115.7Q396 F398 Q456Q396-E458 WeakPolarHBondContact O-CA 3.46Å; Q396-E458 PolarHBondContact O-N 3.47Å; F398-E458 WeakPolarHBondContact CD2-O 3.38Å; F398-E458 HydrophobicContact CE2-CB 3.86Å; F398-E458 HydrophobicContact CE2-CG 3.97Å; F398-E458 HydrophobicContact CZ-CG 4.45Å; Q456-E458 PolarHBondContact O-N 3.33Å
459S96.6Very high90.3Very high20 Ų2070 Ų7014%0.1435%0.353CS..  trans-60.6143.9172.4-68.10000111.7I397 F398 Q456 K457I397-S459 WeakPolarHBondContact CA-O 3.34Å; F398-S459 PolarHBondContact N-O 3.05Å; Q456-S459 PolarHBondContact N-OG 3.39Å; Q456-S459 WeakPolarHBondContact O-CB 3.36Å; Q456-S459 PolarHBondContact O-N 3.27Å; Q456-S459 PolarHBondContact O-OG 3.31Å; K457-S459 PolarHBondContact O-N 3.47Å
460T96.8Very high89.3Confident51 Ų5169.1 Ų69.131%0.31335%0.35SS..EExtended strand (participates in β ladder)trans-108.4117.2176.3-58.20000111.1F398 K400F398-T460 HydrophobicContact CB-CG2 4.38Å; F398-T460 CarbonylContact O-C 3.58Å; F398-T460 VanDerWaalsContact O-CA 3.3Å; F398-T460 WeakPolarHBondContact O-CA 3.42Å; K400-T460 HydrophobicContact CB-CG2 4.28Å; K400-T460 HydrophobicContact CD-CG2 3.95Å; K400-T460 HydrophobicContact CG-CG2 3.93Å
461L97.6Very high89Confident0 Ų070.4 Ų70.40%036%0.356CS..EExtended strand (participates in β ladder)trans-93.4154.1170.1-71.766.4000109.3I397 F398 V399 K400 L437 I438 F439 L444 I455I397-L461 HydrophobicContact CB-CD1 4.43Å; I397-L461 HydrophobicContact CD1-CD1 4.04Å; I397-L461 HydrophobicContact CD1-CD2 4.28Å; F398-L461 PolarHBondContact O-N 2.91Å; V399-L461 CarbonylContact C-O 3.57Å; V399-L461 WeakPolarHBondContact CA-O 3.37Å; V399-L461 HydrophobicContact CG2-CB 4.37Å; K400-L461 PolarHBondContact N-O 2.92Å; L437-L461 HydrophobicContact CB-CD2 4.4Å; L437-L461 HydrophobicContact CD1-CD2 4.31Å; L437-L461 HydrophobicContact CD2-CB 4.49Å; L437-L461 HydrophobicContact CD2-CD2 4.4Å; I438-L461 CarbonylContact O-C 3.6Å; I438-L461 WeakPolarHBondContact O-CA 3.49Å; F439-L461 HydrophobicContact CB-CG 4.28Å; F439-L461 HydrophobicContact CD2-CD1 4.11Å; F439-L461 HydrophobicContact CD2-CG 4.29Å; L444-L461 HydrophobicContact CD1-CD2 3.6Å; L444-L461 HydrophobicContact CD1-CG 4.27Å; I455-L461 HydrophobicContact CD1-CD1 4.29Å; I455-L461 HydrophobicContact CD1-CD2 4.25Å; I455-L461 HydrophobicContact CD1-CG 4.42Å; I455-L461 HydrophobicContact CG2-CD1 3.97Å
462H97.4Very high88.8Confident95 Ų9569.2 Ų69.244%0.4434%0.344SS..EExtended strand (participates in β ladder)trans-107.3129.5172.7-65.573.3000109.6K400 L437 I438K400-H462 CarbonylContact O-C 3.47Å; K400-H462 WeakPolarHBondContact O-CA 3.44Å; L437-H462 CarbonylContact C-O 3.5Å; L437-H462 WeakPolarHBondContact CA-O 3.33Å; I438-H462 HydrophobicContact CB-CB 4.32Å; I438-H462 PolarHBondContact N-O 3.48Å; I438-H462 PolarHBondContact O-N 3.14Å
463L95.8Very high88.7Confident2 Ų264.8 Ų64.81%0.0132%0.32CS..EExtended strand (participates in β ladder)trans-99.2121.7174.7176.562.5000110V399 K400 T401 I424 I430 Q435 R436 L437 L465V399-L463 HydrophobicContact CG1-CB 3.51Å; V399-L463 HydrophobicContact CG1-CD2 4.37Å; K400-L463 PolarHBondContact O-N 3.07Å; T401-L463 HydrophobicContact CG2-CD2 4.37Å; I424-L463 HydrophobicContact CG2-CD2 4.08Å; I430-L463 HydrophobicContact CD1-CD2 4.24Å; Q435-L463 HydrophobicContact CB-CD1 3.71Å; Q435-L463 HydrophobicContact CG-CD1 3.96Å; R436-L463 WeakPolarHBondContact O-CA 3.44Å; L437-L463 HydrophobicContact CD2-CB 4.25Å; L437-L463 HydrophobicContact CD2-CD1 4.09Å; L463-L465 HydrophobicContact CD1-CD2 4.19Å; L463-L465 HydrophobicContact CD2-CD2 4.05Å; L463-L465 HydrophobicContact CG-CD2 4Å
464V92.3Very high88.7Confident40 Ų4065.6 Ų65.624%0.24232%0.324CS..EExtended strand (participates in β ladder)trans-113.5127.2170.6178.80000108.4L402 R436 I438L402-V464 HydrophobicContact CD1-CG1 4.22Å; L402-V464 HydrophobicContact CD1-CG2 4.29Å; L402-V464 HydrophobicContact CD2-CG2 4.36Å; L402-V464 HydrophobicContact CG-CG2 4.36Å; R436-V464 HydrophobicContact CB-CB 4.31Å; R436-V464 WeakPolarHBondContact CB-O 3.5Å; R436-V464 PolarHBondContact N-O 3.32Å; R436-V464 PolarHBondContact O-N 3.43Å; I438-V464 HydrophobicContact CD1-CB 4.48Å; I438-V464 HydrophobicContact CD1-CG2 3.68Å
465L88.5Confident88.8Confident93 Ų9360.4 Ų60.449%0.48730%0.296SS..EExtended strand (participates in β ladder)trans-85.5131.1178.7-57.1-177.5000110.4I430 Q434 L463I430-L465 HydrophobicContact CD1-CD1 4.39Å; I430-L465 HydrophobicContact CD1-CD2 3.98Å; I430-L465 HydrophobicContact CG2-CD2 3.65Å; Q434-L465 CarbonylContact O-C 3.6Å; Q434-L465 WeakPolarHBondContact O-CA 3.33Å; L463-L465 HydrophobicContact CD1-CD2 4.19Å; L463-L465 HydrophobicContact CD2-CD2 4.05Å; L463-L465 HydrophobicContact CG-CD2 4Å
466R82.9Confident88.8Confident95 Ų9564.2 Ų64.236%0.35831%0.313SS..  trans-86.8132170.4-55.7176.391.9137.9-9.1108Q434 R436 R468Q434-R466 PolarHBondContact O-N 3.49Å; R436-R466 HydrophobicContact CG-CG 3.82Å; R466-R468 VanDerWaalsContact C-N 3.26Å; R466-R468 PolarHBondContact O-N 2.88Å
467L69.6Low88.6Confident163 Ų16360 Ų6085%0.85330%0.295SS*.SBendtrans-72.4-21.3176.8-67.1170.6000113.1
468R66.6Low88.2Confident193 Ų19362 Ų6273%0.72831%0.309SS*.SBendtrans-150110.4-179.4-61.8-173.2-164.7173.34108.6R466R466-R468 VanDerWaalsContact C-N 3.26Å; R466-R468 PolarHBondContact O-N 2.88Å
469G61.5Low87.7Confident40 Ų4062 Ų6241%0.41232%0.318SS..  trans-138.6-22.9-176.500000113.8
470G75.8Confident87.1Confident9 Ų963.6 Ų63.69%0.09334%0.338CS..SBendtrans-111.3-168.4-162.100000116.7D433 Q472 E486D433-G470 WeakPolarHBondContact OD2-CA 3.5Å; D433-G470 PolarHBondContact OD2-N 3Å; G470-Q472 PolarHBondContact O-N 2.85Å; G470-E486 PolarHBondContact N-OE2 3.1Å; G470-E486 VanDerWaalsContact N-OE2 3.13Å
471M89.7Confident86.9Confident27 Ų2766 Ų6613%0.13334%0.344CS..EExtended strand (participates in β ladder)trans-63.6120.8162.9174.1-175.3175.300108.1I473 V487 P489 I531 K533M471-I473 HydrophobicContact CE-CG2 4.11Å; M471-V487 WeakPolarHBondContact CB-O 3.45Å; M471-V487 HydrophobicContact CE-CG2 4.48Å; M471-V487 HydrophobicContact CG-CG2 4.09Å; M471-V487 WeakPolarHBondContact O-CG2 3.38Å; M471-V487 PolarHBondContact O-N 3.26Å; M471-V487 VanDerWaalsContact O-O 3.06Å; M471-V487 HydrophobicContact SD-CG2 4.35Å; M471-P489 HydrophobicContact SD-CG 3.83Å; M471-I531 HydrophobicContact CE-CG2 4.39Å; M471-I531 WeakPolarHBondContact CE-O 3.44Å; M471-K533 HydrophobicContact CG-CB 4.07Å; M471-K533 HydrophobicContact CG-CG 4.46Å
472Q91.4Very high86.8Confident39 Ų3969.2 Ų69.218%0.18236%0.363CS..EExtended strand (participates in β ladder)trans-104.5141.8174.8-67.6179.124.800109.2G470 T484 L485 E486 E534G470-Q472 PolarHBondContact O-N 2.85Å; Q472-T484 HydrophobicContact CB-CG2 4.14Å; Q472-T484 HydrophobicContact CG-CG2 4.3Å; Q472-T484 VanDerWaalsContact OE1-CG2 3.26Å; Q472-L485 CarbonylContact C-O 3.57Å; Q472-L485 VanDerWaalsContact CA-O 3.25Å; Q472-L485 WeakPolarHBondContact CA-O 3.44Å; Q472-E486 WeakPolarHBondContact CG-OE1 3.29Å; Q472-E486 PolarHBondContact NE2-OE1 3.23Å; Q472-E534 WeakPolarHBondContact O-CA 3.41Å; Q472-E534 PolarHBondContact O-N 3.33Å
473I95.8Very high86.6Confident0 Ų065 Ų650%034%0.344CS..EExtended strand (participates in β ladder)trans-123.5157.8167.362.6173.3000109.2M471 L485 V487 V496 L526 I531 L537M471-I473 HydrophobicContact CE-CG2 4.11Å; I473-L485 HydrophobicContact CG1-CB 4.03Å; I473-L485 PolarHBondContact N-O 2.82Å; I473-L485 PolarHBondContact O-N 3.11Å; I473-V487 HydrophobicContact CB-CG2 4.33Å; I473-V487 HydrophobicContact CD1-CG1 3.85Å; I473-V487 HydrophobicContact CD1-CG2 4.06Å; I473-V487 HydrophobicContact CG1-CG1 3.94Å; I473-V487 HydrophobicContact CG1-CG2 3.83Å; I473-V487 HydrophobicContact CG2-CG2 3.76Å; I473-V496 HydrophobicContact CD1-CG1 4.29Å; I473-L526 HydrophobicContact CD1-CD1 4.2Å; I473-L526 HydrophobicContact CD1-CD2 4.25Å; I473-I531 HydrophobicContact CG2-CG2 3.88Å; I473-L537 HydrophobicContact CB-CD1 4.37Å; I473-L537 HydrophobicContact CD1-CD1 3.99Å; I473-L537 HydrophobicContact CD1-CD2 4.34Å
474F97.1Very high86.4Confident54 Ų5467.3 Ų67.324%0.23736%0.358CS..EExtended strand (participates in β ladder)trans-108.2136.7177.6-58.2-69.9000109.9T482 I483 T484 E534 S535 T536 L537F474-T482 HydrophobicContact CB-CG2 3.89Å; F474-T482 HydrophobicContact CD1-CG2 3.93Å; F474-T482 HydrophobicContact CG-CG2 4.23Å; F474-I483 CarbonylContact C-O 3.6Å; F474-I483 WeakPolarHBondContact CA-O 3.37Å; F474-T484 HydrophobicContact CD1-CG2 4.2Å; F474-T484 HydrophobicContact CE1-CG2 3.9Å; F474-E534 WeakPolarHBondContact CD2-O 3.31Å; F474-E534 HydrophobicContact CE2-CB 3.87Å; F474-E534 HydrophobicContact CE2-CG 3.94Å; F474-E534 HydrophobicContact CZ-CG 4.46Å; F474-S535 PolarHBondContact N-O 3.04Å; F474-T536 HydrophobicContact CB-CG2 4.45Å; F474-T536 CarbonylContact O-C 3.52Å; F474-T536 VanDerWaalsContact O-CA 3.3Å; F474-T536 WeakPolarHBondContact O-CA 3.06Å; F474-L537 PolarHBondContact O-N 3.43Å
475V97.1Very high86.4Confident0 Ų065.4 Ų65.40%035%0.347CS..EExtended strand (participates in β ladder)trans-116.8114.5173.1-177.20000107.9I483 L485 I500 L513 L537 L539V475-I483 HydrophobicContact CB-CB 4.34Å; V475-I483 PolarHBondContact N-O 2.88Å; V475-I483 PolarHBondContact O-N 3.25Å; V475-L485 HydrophobicContact CG2-CD1 3.58Å; V475-L485 HydrophobicContact CG2-CG 4.22Å; V475-I500 HydrophobicContact CG1-CD1 4.13Å; V475-I500 HydrophobicContact CG2-CD1 4.14Å; V475-L513 HydrophobicContact CG1-CD2 4.09Å; V475-L537 CarbonylContact C-O 3.42Å; V475-L537 WeakPolarHBondContact CA-O 3.5Å; V475-L537 HydrophobicContact CG2-CB 4.37Å; V475-L539 HydrophobicContact CG1-CB 3.55Å; V475-L539 HydrophobicContact CG1-CD2 4.43Å
476K96.3Very high86.4Confident86 Ų8662.2 Ų62.237%0.37433%0.33SS..EExtended strand (participates in β ladder)trans-93.9127.3175.9-79.3-172.2178.9-178.40110.8K481 T482 T536 L537 H538 L539K476-K481 WeakPolarHBondContact CA-O 3.46Å; K476-T482 WeakPolarHBondContact CE-OG1 3.49Å; K476-T482 HydrophobicContact CG-CG2 4.3Å; K476-T482 WeakPolarHBondContact CG-OG1 3.38Å; K476-T536 HydrophobicContact CB-CG2 4.32Å; K476-T536 HydrophobicContact CD-CG2 3.91Å; K476-T536 HydrophobicContact CG-CG2 3.87Å; K476-L537 PolarHBondContact N-O 3.18Å; K476-H538 WeakPolarHBondContact O-CA 3.42Å; K476-L539 PolarHBondContact O-N 3.33Å
477T89.7Confident86.8Confident26 Ų2657.9 Ų57.916%0.1631%0.314CS..EExtended strand (participates in β ladder)trans-79.2164.3170.168.40000110.6T479 G480 K481 I483 L539T477-T479 PolarHBondContact O-N 3.28Å; T477-T479 PolarHBondContact OG1-N 2.76Å; T477-T479 PolarHBondContact OG1-OG1 2.88Å; T477-G480 PolarHBondContact O-N 3.2Å; T477-K481 HydrophobicContact CG2-CB 4.35Å; T477-K481 PolarHBondContact N-O 2.88Å; T477-K481 WeakPolarHBondContact OG1-CB 3.43Å; T477-K481 PolarHBondContact OG1-N 2.91Å; T477-K481 PolarHBondContact OG1-O 3.1Å; T477-I483 HydrophobicContact CG2-CD1 3.9Å; T477-L539 HydrophobicContact CG2-CD2 4.48Å
478L82Confident87.8Confident141 Ų14152 Ų5274%0.73828%0.282SS*.THydrogen-bonded Turntrans-60.9-22.1172.2-68.8175.9000113.8G480 V540L478-G480 PolarHBondContact O-N 3.29Å; L478-V540 HydrophobicContact CD1-CG1 4.21Å; L478-V540 HydrophobicContact CD1-CG2 4.46Å; L478-V540 HydrophobicContact CD2-CG2 4.16Å; L478-V540 HydrophobicContact CG-CG2 4.37Å
479T81.4Confident89Confident128 Ų12846.2 Ų46.279%0.78527%0.269SS*.THydrogen-bonded Turntrans-79.9-3.7175.358.30000113.1T477 K481T477-T479 PolarHBondContact O-N 3.28Å; T477-T479 PolarHBondContact OG1-N 2.76Å; T477-T479 PolarHBondContact OG1-OG1 2.88Å; T479-K481 VanDerWaalsContact C-N 3.34Å
480G84.1Confident90.5Very high53 Ų5347.8 Ų47.855%0.54627%0.274SS..SBendtrans86.7-2.3-176.900000114.5T477 L478 T482T477-G480 PolarHBondContact O-N 3.2Å; L478-G480 PolarHBondContact O-N 3.29Å; G480-T482 PolarHBondContact O-N 2.78Å
481K92.6Very high91.2Very high103 Ų10348 Ų4845%0.44827%0.273SS..  trans-65.1132.9174.1-174.5-178.3172.9-170.40109.2K476 T477 T479 E504K476-K481 WeakPolarHBondContact CA-O 3.46Å; T477-K481 HydrophobicContact CG2-CB 4.35Å; T477-K481 PolarHBondContact N-O 2.88Å; T477-K481 WeakPolarHBondContact OG1-CB 3.43Å; T477-K481 PolarHBondContact OG1-N 2.91Å; T477-K481 PolarHBondContact OG1-O 3.1Å; T479-K481 VanDerWaalsContact C-N 3.34Å; K481-E504 WeakPolarHBondContact CE-OE1 3.39Å; K481-E504 IonicContact NZ-OE1 3.94Å; K481-E504 PolarHBondContact NZ-OE1 3.13Å; K481-E504 IonicContact NZ-OE2 2.72Å; K481-E504 PolarHBondContact NZ-OE2 2.8Å
482T94.6Very high91.5Very high66 Ų6648.5 Ų48.541%0.40528%0.278SS..EExtended strand (participates in β ladder)trans-105.7126.3176-56.10000109.4F474 K476 G480F474-T482 HydrophobicContact CB-CG2 3.89Å; F474-T482 HydrophobicContact CD1-CG2 3.93Å; F474-T482 HydrophobicContact CG-CG2 4.23Å; K476-T482 WeakPolarHBondContact CE-OG1 3.49Å; K476-T482 HydrophobicContact CG-CG2 4.3Å; K476-T482 WeakPolarHBondContact CG-OG1 3.38Å; G480-T482 PolarHBondContact O-N 2.78Å
483I93Very high91.8Very high6 Ų646.7 Ų46.73%0.03127%0.269CS..EExtended strand (participates in β ladder)trans-108.1128.1177.2-54.2149.3000107.3F474 V475 T477 L485 K503 E504F474-I483 CarbonylContact C-O 3.6Å; F474-I483 WeakPolarHBondContact CA-O 3.37Å; V475-I483 HydrophobicContact CB-CB 4.34Å; V475-I483 PolarHBondContact N-O 2.88Å; V475-I483 PolarHBondContact O-N 3.25Å; T477-I483 HydrophobicContact CG2-CD1 3.9Å; I483-L485 HydrophobicContact CG2-CD2 4.17Å; I483-K503 HydrophobicContact CG2-CB 4.49Å; I483-K503 HydrophobicContact CG2-CD 4.12Å; I483-E504 HydrophobicContact CD1-CG 3.58Å; I483-E504 HydrophobicContact CG1-CG 3.96Å; I483-E504 HydrophobicContact CG2-CG 4.43Å
484T93.5Very high91.7Very high51 Ų5152.3 Ų52.331%0.31330%0.295SS..EExtended strand (participates in β ladder)trans-93.9128.4174.8-51.30000109.5Q472 F474 K503Q472-T484 HydrophobicContact CB-CG2 4.14Å; Q472-T484 HydrophobicContact CG-CG2 4.3Å; Q472-T484 VanDerWaalsContact OE1-CG2 3.26Å; F474-T484 HydrophobicContact CD1-CG2 4.2Å; F474-T484 HydrophobicContact CE1-CG2 3.9Å; T484-K503 PolarHBondContact O-NZ 2.6Å
485L91.4Very high91.5Very high1 Ų153.3 Ų53.31%0.00530%0.303CS..EExtended strand (participates in β ladder)trans-116.3137.8175.8-61.9177.2000110.5Q472 I473 V475 I483 V487 V496 K499 I500 K503Q472-L485 CarbonylContact C-O 3.57Å; Q472-L485 VanDerWaalsContact CA-O 3.25Å; Q472-L485 WeakPolarHBondContact CA-O 3.44Å; I473-L485 HydrophobicContact CG1-CB 4.03Å; I473-L485 PolarHBondContact N-O 2.82Å; I473-L485 PolarHBondContact O-N 3.11Å; V475-L485 HydrophobicContact CG2-CD1 3.58Å; V475-L485 HydrophobicContact CG2-CG 4.22Å; I483-L485 HydrophobicContact CG2-CD2 4.17Å; L485-V487 HydrophobicContact CB-CG1 4.06Å; L485-V496 HydrophobicContact CD1-CG1 3.93Å; L485-K499 HydrophobicContact CD2-CB 4.18Å; L485-I500 HydrophobicContact CD1-CD1 4.12Å; L485-I500 HydrophobicContact CD1-CG1 3.57Å; L485-I500 HydrophobicContact CD2-CG1 4.37Å; L485-K503 HydrophobicContact CD2-CD 3.94Å; L485-K503 HydrophobicContact CD2-CG 4.46Å
486E88.7Confident91.4Very high26 Ų2653.3 Ų53.312%0.12130%0.303CS..EExtended strand (participates in β ladder)trans-87.8125166.9-58.6-75.5153.800108G470 Q472 K499G470-E486 PolarHBondContact N-OE2 3.1Å; G470-E486 VanDerWaalsContact N-OE2 3.13Å; Q472-E486 WeakPolarHBondContact CG-OE1 3.29Å; Q472-E486 PolarHBondContact NE2-OE1 3.23Å; E486-K499 PolarHBondContact O-NZ 3.19Å
487V91.3Very high91.3Very high3 Ų349.7 Ų49.72%0.01829%0.287CS..EExtended strand (participates in β ladder)trans-140.7159.2-172.3-64.10000111.5M471 I473 L485 D491 V496 K499 L526M471-V487 WeakPolarHBondContact CB-O 3.45Å; M471-V487 HydrophobicContact CE-CG2 4.48Å; M471-V487 HydrophobicContact CG-CG2 4.09Å; M471-V487 WeakPolarHBondContact O-CG2 3.38Å; M471-V487 PolarHBondContact O-N 3.26Å; M471-V487 VanDerWaalsContact O-O 3.06Å; M471-V487 HydrophobicContact SD-CG2 4.35Å; I473-V487 HydrophobicContact CB-CG2 4.33Å; I473-V487 HydrophobicContact CD1-CG1 3.85Å; I473-V487 HydrophobicContact CD1-CG2 4.06Å; I473-V487 HydrophobicContact CG1-CG1 3.94Å; I473-V487 HydrophobicContact CG1-CG2 3.83Å; I473-V487 HydrophobicContact CG2-CG2 3.76Å; L485-V487 HydrophobicContact CB-CG1 4.06Å; V487-D491 VanDerWaalsContact CA-OD2 3.26Å; V487-D491 WeakPolarHBondContact CA-OD2 3.28Å; V487-D491 WeakPolarHBondContact CB-OD2 3.32Å; V487-V496 HydrophobicContact CG1-CG2 4.36Å; V487-K499 HydrophobicContact CG1-CD 4.35Å; V487-L526 HydrophobicContact CB-CD1 3.56Å; V487-L526 HydrophobicContact CG1-CD1 4.07Å; V487-L526 HydrophobicContact CG2-CD1 3.49Å; V487-L526 VanDerWaalsContact CG2-CD1 3.49Å
488E89.7Confident91.4Very high40 Ų4050.2 Ų50.219%0.18729%0.294CS..  trans-107.1150.1167.4-65.1-175.5150.200109.9Q425 S490 D491Q425-E488 PolarHBondContact NE2-OE2 3.39Å; E488-S490 PolarHBondContact O-N 2.95Å; E488-S490 VanDerWaalsContact O-N 3.08Å; E488-D491 PolarHBondContact N-OD2 3.21Å; E488-D491 VanDerWaalsContact O-CB 3.29Å; E488-D491 WeakPolarHBondContact O-CB 3.49Å; E488-D491 PolarHBondContact O-N 2.82Å
489P92.6Very high91.8Very high71 Ų7146 Ų4646%0.46127%0.27SS..THydrogen-bonded Turntrans-56.1-27.1176.5-24.633.1000114M471 S527M471-P489 HydrophobicContact SD-CG 3.83Å; P489-S527 WeakPolarHBondContact O-CB 3.42Å; P489-S527 PolarHBondContact O-N 3.29Å
490S92Very high92.4Very high74 Ų7439.9 Ų39.952%0.51723%0.233SC..THydrogen-bonded Turntrans-79.4-11.617642.80000114.2E488 T492 T525E488-S490 PolarHBondContact O-N 2.95Å; E488-S490 VanDerWaalsContact O-N 3.08Å; S490-T492 PolarHBondContact O-N 2.82Å; S490-T525 WeakPolarHBondContact O-CG2 3.5Å
491D91.7Very high92.6Very high14 Ų1439.9 Ų39.98%0.07522%0.219CC..  trans-59.3130.3178.5-82.8-24.1000110.1V487 E488 N495 V496 K499 T525 L526V487-D491 VanDerWaalsContact CA-OD2 3.26Å; V487-D491 WeakPolarHBondContact CA-OD2 3.28Å; V487-D491 WeakPolarHBondContact CB-OD2 3.32Å; E488-D491 PolarHBondContact N-OD2 3.21Å; E488-D491 VanDerWaalsContact O-CB 3.29Å; E488-D491 WeakPolarHBondContact O-CB 3.49Å; E488-D491 PolarHBondContact O-N 2.82Å; D491-N495 HydrophobicContact CB-CB 4.48Å; D491-V496 HydrophobicContact CB-CG2 4.26Å; D491-K499 IonicContact OD1-NZ 2.76Å; D491-K499 IonicContact OD2-NZ 2.63Å; D491-K499 PolarHBondContact OD2-NZ 3.23Å; D491-T525 CarbonylContact O-C 3.58Å; D491-T525 WeakPolarHBondContact O-CA 3.21Å; D491-L526 HydrophobicContact CB-CD1 4.27Å; D491-L526 HydrophobicContact CB-CG 4.48Å; D491-L526 PolarHBondContact O-N 3.01Å
492T95.3Very high92.2Very high37 Ų3741.2 Ų41.223%0.22723%0.231CC..BIsolated β-bridgetrans-72.1157.2170.863.10000110.7S490 E494 N495 V496 R524S490-T492 PolarHBondContact O-N 2.82Å; T492-E494 PolarHBondContact O-N 3.14Å; T492-N495 WeakPolarHBondContact O-CB 3.3Å; T492-N495 PolarHBondContact O-N 3.11Å; T492-N495 VanDerWaalsContact O-N 3.08Å; T492-N495 PolarHBondContact OG1-N 2.99Å; T492-N495 VanDerWaalsContact OG1-N 3.16Å; T492-N495 PolarHBondContact OG1-OD1 3.37Å; T492-V496 WeakPolarHBondContact O-CG2 3.43Å; T492-V496 PolarHBondContact O-N 3.13Å; T492-R524 CarbonylContact C-O 3.47Å; T492-R524 VanDerWaalsContact CA-O 3.24Å; T492-R524 WeakPolarHBondContact CA-O 3.49Å
493I97.1Very high91.9Very high0 Ų043.8 Ų43.80%024%0.236CC..Hα-helixtrans-62.4-32.2175-61.6-56.7000111.3V496 K497 L513 L520 E521 D522 R524 L526 Y529I493-V496 PolarHBondContact O-N 2.9Å; I493-K497 WeakPolarHBondContact O-CG 3.41Å; I493-K497 PolarHBondContact O-N 3.32Å; I493-L513 HydrophobicContact CG2-CD1 4.27Å; I493-L520 HydrophobicContact CD1-CB 3.9Å; I493-L520 HydrophobicContact CD1-CD1 3.63Å; I493-L520 HydrophobicContact CD1-CG 4.29Å; I493-L520 HydrophobicContact CG1-CB 3.9Å; I493-L520 HydrophobicContact CG2-CB 3.86Å; I493-E521 VanDerWaalsContact CB-O 3.28Å; I493-E521 WeakPolarHBondContact CB-O 3.43Å; I493-E521 VanDerWaalsContact CG1-O 3.28Å; I493-E521 WeakPolarHBondContact CG1-O 3.38Å; I493-D522 PolarHBondContact N-O 3.43Å; I493-R524 WeakPolarHBondContact CG1-O 3.49Å; I493-R524 PolarHBondContact N-O 3.24Å; I493-L526 HydrophobicContact CD1-CD2 4.02Å; I493-Y529 HydrophobicContact CD1-CD2 4.46Å; I493-Y529 HydrophobicContact CG1-CE2 4.23Å
494E94.4Very high91.7Very high119 Ų11946.7 Ų46.756%0.55625%0.249SC*.Hα-helixtrans-58.8-47.1169.9-170.5172.7-16600112.1T492 V496 K497 A498 D522T492-E494 PolarHBondContact O-N 3.14Å; E494-V496 VanDerWaalsContact C-N 3.32Å; E494-V496 PolarHBondContact O-N 3.04Å; E494-K497 WeakPolarHBondContact O-CB 3.28Å; E494-K497 PolarHBondContact O-N 3.25Å; E494-K497 VanDerWaalsContact O-N 3.15Å; E494-A498 PolarHBondContact O-N 3.46Å; E494-D522 HydrophobicContact CB-CB 4.22Å; E494-D522 PolarHBondContact N-O 3.35Å
495N92.2Very high91.2Very high75 Ų7547 Ų4740%0.40126%0.263SS..Hα-helixtrans-61.5-41.1175.7-67.2-3.7000111.6D491 T492 K497 A498 K499D491-N495 HydrophobicContact CB-CB 4.48Å; T492-N495 WeakPolarHBondContact O-CB 3.3Å; T492-N495 PolarHBondContact O-N 3.11Å; T492-N495 VanDerWaalsContact O-N 3.08Å; T492-N495 PolarHBondContact OG1-N 2.99Å; T492-N495 VanDerWaalsContact OG1-N 3.16Å; T492-N495 PolarHBondContact OG1-OD1 3.37Å; N495-K497 VanDerWaalsContact C-N 3.29Å; N495-K497 PolarHBondContact O-N 3.47Å; N495-A498 PolarHBondContact O-N 3Å; N495-K499 WeakPolarHBondContact O-CG 3.44Å; N495-K499 PolarHBondContact O-N 2.83Å
496V95.6Very high90.9Very high0 Ų048.2 Ų48.20%027%0.27CS..Hα-helixtrans-62.3-39.5176.8176.40000110.8I473 L485 V487 D491 T492 I493 E494 K499 I500 L513 L526I473-V496 HydrophobicContact CD1-CG1 4.29Å; L485-V496 HydrophobicContact CD1-CG1 3.93Å; V487-V496 HydrophobicContact CG1-CG2 4.36Å; D491-V496 HydrophobicContact CB-CG2 4.26Å; T492-V496 WeakPolarHBondContact O-CG2 3.43Å; T492-V496 PolarHBondContact O-N 3.13Å; I493-V496 PolarHBondContact O-N 2.9Å; E494-V496 VanDerWaalsContact C-N 3.32Å; E494-V496 PolarHBondContact O-N 3.04Å; V496-K499 WeakPolarHBondContact O-CB 3.32Å; V496-K499 PolarHBondContact O-N 3.1Å; V496-I500 HydrophobicContact CG1-CD1 4.36Å; V496-I500 WeakPolarHBondContact O-CG1 3.5Å; V496-I500 PolarHBondContact O-N 3.21Å; V496-I500 VanDerWaalsContact O-N 3.09Å; V496-L513 HydrophobicContact CB-CD1 4.44Å; V496-L513 HydrophobicContact CG1-CD1 3.84Å; V496-L526 HydrophobicContact CG2-CD1 4.17Å; V496-L526 HydrophobicContact CG2-CD2 3.97Å; V496-L526 HydrophobicContact CG2-CG 4.13Å
497K94.4Very high90.6Very high9 Ų948.1 Ų48.14%0.03927%0.271CS..Hα-helixtrans-66.3-42175.6-72.2172.4165.7-171.20112.6I493 E494 N495 K499 I500 Q501 P508 Q511 L513 D522I493-K497 WeakPolarHBondContact O-CG 3.41Å; I493-K497 PolarHBondContact O-N 3.32Å; E494-K497 WeakPolarHBondContact O-CB 3.28Å; E494-K497 PolarHBondContact O-N 3.25Å; E494-K497 VanDerWaalsContact O-N 3.15Å; N495-K497 VanDerWaalsContact C-N 3.29Å; N495-K497 PolarHBondContact O-N 3.47Å; K497-K499 VanDerWaalsContact C-N 3.29Å; K497-K499 PolarHBondContact O-N 2.9Å; K497-I500 WeakPolarHBondContact O-CB 3.19Å; K497-I500 PolarHBondContact O-N 3.27Å; K497-I500 VanDerWaalsContact O-N 3.1Å; K497-Q501 PolarHBondContact O-N 2.72Å; K497-P508 HydrophobicContact CB-CB 3.84Å; K497-P508 HydrophobicContact CB-CG 4.35Å; K497-P508 HydrophobicContact CD-CB 4.23Å; K497-P508 WeakPolarHBondContact CD-O 3.32Å; K497-P508 PolarHBondContact NZ-O 3.09Å; K497-Q511 HydrophobicContact CD-CB 4.32Å; K497-Q511 WeakPolarHBondContact CE-O 3.16Å; K497-Q511 HydrophobicContact CG-CB 4.06Å; K497-Q511 PolarHBondContact NZ-O 3.3Å; K497-Q511 PolarHBondContact O-NE2 3.01Å; K497-Q511 PolarHBondContact O-OE1 3.19Å; K497-L513 HydrophobicContact CG-CD1 3.9Å; K497-L513 HydrophobicContact CG-CG 4.48Å; K497-D522 WeakPolarHBondContact CD-OD1 3.43Å; K497-D522 WeakPolarHBondContact CE-OD1 3.35Å; K497-D522 IonicContact NZ-OD1 2.74Å; K497-D522 PolarHBondContact NZ-OD1 2.98Å; K497-D522 IonicContact NZ-OD2 2.62Å; K497-D522 PolarHBondContact NZ-OD2 3.22Å
498A90.8Very high90.5Very high37 Ų3749.1 Ų49.131%0.30628%0.278SS..Hα-helixtrans-57.9-44.1172.700000110.9E494 N495 I500 Q501 D502E494-A498 PolarHBondContact O-N 3.46Å; N495-A498 PolarHBondContact O-N 3Å; A498-I500 VanDerWaalsContact C-N 3.25Å; A498-I500 PolarHBondContact O-N 3.23Å; A498-Q501 WeakPolarHBondContact O-CA 3.28Å; A498-Q501 VanDerWaalsContact O-CB 3.29Å; A498-Q501 WeakPolarHBondContact O-CB 3.38Å; A498-Q501 PolarHBondContact O-N 3.26Å; A498-D502 PolarHBondContact O-N 2.78Å
499K92.2Very high90.2Very high52 Ų5251 Ų5123%0.22629%0.289CS..Hα-helixtrans-60.8-31.5175.1-70.4177.4176.1-172.10113.6L485 E486 V487 D491 N495 V496 K497 K503L485-K499 HydrophobicContact CD2-CB 4.18Å; E486-K499 PolarHBondContact O-NZ 3.19Å; V487-K499 HydrophobicContact CG1-CD 4.35Å; D491-K499 IonicContact OD1-NZ 2.76Å; D491-K499 IonicContact OD2-NZ 2.63Å; D491-K499 PolarHBondContact OD2-NZ 3.23Å; N495-K499 WeakPolarHBondContact O-CG 3.44Å; N495-K499 PolarHBondContact O-N 2.83Å; V496-K499 WeakPolarHBondContact O-CB 3.32Å; V496-K499 PolarHBondContact O-N 3.1Å; K497-K499 VanDerWaalsContact C-N 3.29Å; K497-K499 PolarHBondContact O-N 2.9Å; K499-K503 PolarHBondContact O-N 2.87Å
500I92.7Very high89.9Confident0 Ų049 Ų490%027%0.274CS..Hα-helixtrans-73.2-40.4173.1-66.2164.4000110.7V475 L485 V496 K497 A498 D502 K503 E504 I506 Q511 L513 L539V475-I500 HydrophobicContact CG1-CD1 4.13Å; V475-I500 HydrophobicContact CG2-CD1 4.14Å; L485-I500 HydrophobicContact CD1-CD1 4.12Å; L485-I500 HydrophobicContact CD1-CG1 3.57Å; L485-I500 HydrophobicContact CD2-CG1 4.37Å; V496-I500 HydrophobicContact CG1-CD1 4.36Å; V496-I500 WeakPolarHBondContact O-CG1 3.5Å; V496-I500 PolarHBondContact O-N 3.21Å; V496-I500 VanDerWaalsContact O-N 3.09Å; K497-I500 WeakPolarHBondContact O-CB 3.19Å; K497-I500 PolarHBondContact O-N 3.27Å; K497-I500 VanDerWaalsContact O-N 3.1Å; A498-I500 VanDerWaalsContact C-N 3.25Å; A498-I500 PolarHBondContact O-N 3.23Å; I500-D502 VanDerWaalsContact C-N 3.3Å; I500-D502 PolarHBondContact O-N 2.91Å; I500-K503 PolarHBondContact O-N 2.8Å; I500-E504 WeakPolarHBondContact O-CB 3.4Å; I500-E504 PolarHBondContact O-N 3.49Å; I500-I506 HydrophobicContact CG2-CD1 4.44Å; I500-Q511 VanDerWaalsContact CD1-OE1 3.3Å; I500-L513 HydrophobicContact CD1-CD1 3.99Å; I500-L513 HydrophobicContact CD1-CD2 3.66Å; I500-L513 HydrophobicContact CD1-CG 4.33Å; I500-L539 HydrophobicContact CG2-CD2 4Å
501Q89.2Confident89.9Confident54 Ų5445.5 Ų45.525%0.25225%0.249SC..Hα-helixtrans-58.5-45.3174.5-177.4-178.828.700110.5K497 A498 K503 G505 I506 P508 E564K497-Q501 PolarHBondContact O-N 2.72Å; A498-Q501 WeakPolarHBondContact O-CA 3.28Å; A498-Q501 VanDerWaalsContact O-CB 3.29Å; A498-Q501 WeakPolarHBondContact O-CB 3.38Å; A498-Q501 PolarHBondContact O-N 3.26Å; Q501-K503 VanDerWaalsContact C-N 3.27Å; Q501-K503 PolarHBondContact O-N 2.76Å; Q501-G505 WeakPolarHBondContact O-CA 3.1Å; Q501-G505 PolarHBondContact O-N 3.22Å; Q501-I506 VanDerWaalsContact CA-O 3.29Å; Q501-I506 WeakPolarHBondContact CA-O 3.39Å; Q501-I506 WeakPolarHBondContact CB-O 3.25Å; Q501-P508 HydrophobicContact CB-CG 4.46Å; Q501-P508 VanDerWaalsContact CD-CD 3.5Å; Q501-E564 PolarHBondContact NE2-OE1 2.81Å; Q501-E564 VanDerWaalsContact NE2-OE1 3.16Å
502D84.2Confident90Very high131 Ų13149.8 Ų49.870%0.70126%0.264SS*.Hα-helixtrans-62-35.3178.9-66.9-25.9000112.7A498 I500A498-D502 PolarHBondContact O-N 2.78Å; I500-D502 VanDerWaalsContact C-N 3.3Å; I500-D502 PolarHBondContact O-N 2.91Å
503K87.3Confident90Very high120 Ų12048 Ų4852%0.52225%0.253SS..Hα-helixtrans-86.3-35.5-178.5-75.4-155.4178.8-164.70114.7I483 T484 L485 K499 I500 Q501I483-K503 HydrophobicContact CG2-CB 4.49Å; I483-K503 HydrophobicContact CG2-CD 4.12Å; T484-K503 PolarHBondContact O-NZ 2.6Å; L485-K503 HydrophobicContact CD2-CD 3.94Å; L485-K503 HydrophobicContact CD2-CG 4.46Å; K499-K503 PolarHBondContact O-N 2.87Å; I500-K503 PolarHBondContact O-N 2.8Å; Q501-K503 VanDerWaalsContact C-N 3.27Å; Q501-K503 PolarHBondContact O-N 2.76Å
504E89.2Confident90Very high66 Ų6650.1 Ų50.131%0.30826%0.264SS..Hα-helixtrans-122.7-4.9-168.9-63.5-70.1142.600113.3K481 I483 I500 I506K481-E504 WeakPolarHBondContact CE-OE1 3.39Å; K481-E504 IonicContact NZ-OE1 3.94Å; K481-E504 PolarHBondContact NZ-OE1 3.13Å; K481-E504 IonicContact NZ-OE2 2.72Å; K481-E504 PolarHBondContact NZ-OE2 2.8Å; I483-E504 HydrophobicContact CD1-CG 3.58Å; I483-E504 HydrophobicContact CG1-CG 3.96Å; I483-E504 HydrophobicContact CG2-CG 4.43Å; I500-E504 WeakPolarHBondContact O-CB 3.4Å; I500-E504 PolarHBondContact O-N 3.49Å; E504-I506 VanDerWaalsContact C-N 3.27Å; E504-I506 HydrophobicContact CB-CD1 3.74Å; E504-I506 HydrophobicContact CB-CG1 4Å; E504-I506 PolarHBondContact O-N 2.88Å
505G83.1Confident90.1Very high59 Ų5946.4 Ų46.461%0.60825%0.246SC*.  trans72.715.2179.800000114.5Q501 P507Q501-G505 WeakPolarHBondContact O-CA 3.1Å; Q501-G505 PolarHBondContact O-N 3.22Å; G505-P507 WeakPolarHBondContact O-CD 3.27Å
506I85.1Confident90.2Very high26 Ų2647.1 Ų47.113%0.13326%0.263CS..  trans-90.8118.5-175.2-56.6164.1000109.1I500 Q501 E504 Q510 Q511 L539 L541I500-I506 HydrophobicContact CG2-CD1 4.44Å; Q501-I506 VanDerWaalsContact CA-O 3.29Å; Q501-I506 WeakPolarHBondContact CA-O 3.39Å; Q501-I506 WeakPolarHBondContact CB-O 3.25Å; E504-I506 VanDerWaalsContact C-N 3.27Å; E504-I506 HydrophobicContact CB-CD1 3.74Å; E504-I506 HydrophobicContact CB-CG1 4Å; E504-I506 PolarHBondContact O-N 2.88Å; I506-Q510 HydrophobicContact CG2-CB 4.42Å; I506-Q511 HydrophobicContact CB-CG 4.33Å; I506-Q511 HydrophobicContact CG2-CG 3.64Å; I506-Q511 PolarHBondContact O-NE2 2.92Å; I506-L539 HydrophobicContact CD1-CD2 3.89Å; I506-L541 HydrophobicContact CD1-CD2 4.2Å; I506-L541 HydrophobicContact CG2-CD2 3.49Å; I506-L541 VanDerWaalsContact CG2-CD2 3.49Å
507P83.4Confident89.9Confident24 Ų2450.9 Ų50.916%0.15630%0.301CS..  trans-58.6138.3178.6-27.937.8000113.8G505 D509 Q510 Q511G505-P507 WeakPolarHBondContact O-CD 3.27Å; P507-D509 VanDerWaalsContact C-N 3.27Å; P507-D509 WeakPolarHBondContact CB-OD1 3.46Å; P507-D509 PolarHBondContact O-N 3.47Å; P507-Q510 HydrophobicContact CB-CG 4.35Å; P507-Q510 WeakPolarHBondContact O-CB 3.25Å; P507-Q510 PolarHBondContact O-N 2.92Å; P507-Q511 WeakPolarHBondContact O-CG 3.39Å; P507-Q511 PolarHBondContact O-N 3.35Å
508P87.8Confident89.9Confident24 Ų2457.1 Ų57.116%0.15633%0.328CS..THydrogen-bonded Turntrans-55.9-32.1-176.8-30.938000115.7K497 Q501 Q510 Q511 E564K497-P508 HydrophobicContact CB-CB 3.84Å; K497-P508 HydrophobicContact CB-CG 4.35Å; K497-P508 HydrophobicContact CD-CB 4.23Å; K497-P508 WeakPolarHBondContact CD-O 3.32Å; K497-P508 PolarHBondContact NZ-O 3.09Å; Q501-P508 HydrophobicContact CB-CG 4.46Å; Q501-P508 VanDerWaalsContact CD-CD 3.5Å; P508-Q510 VanDerWaalsContact C-N 3.3Å; P508-Q510 PolarHBondContact O-N 2.92Å; P508-Q511 PolarHBondContact O-N 2.93Å; P508-E564 WeakPolarHBondContact CD-OE1 3.23Å
509D83.5Confident90.1Very high79 Ų7959.1 Ų59.142%0.42233%0.331SS..THydrogen-bonded Turntrans-68.5-29.4177.966.6-34.5000112.5P507 Q511P507-D509 VanDerWaalsContact C-N 3.27Å; P507-D509 WeakPolarHBondContact CB-OD1 3.46Å; P507-D509 PolarHBondContact O-N 3.47Å; D509-Q511 VanDerWaalsContact C-N 3.34Å
510Q86.2Confident90.3Very high30 Ų3056.8 Ų56.814%0.1432%0.321CS..THydrogen-bonded Turntrans-81.1-14.8173.4-62.4-177.4800113I506 P507 P508 L541 R542 E562I506-Q510 HydrophobicContact CG2-CB 4.42Å; P507-Q510 HydrophobicContact CB-CG 4.35Å; P507-Q510 WeakPolarHBondContact O-CB 3.25Å; P507-Q510 PolarHBondContact O-N 2.92Å; P508-Q510 VanDerWaalsContact C-N 3.3Å; P508-Q510 PolarHBondContact O-N 2.92Å; Q510-L541 CarbonylContact O-C 3.55Å; Q510-L541 WeakPolarHBondContact O-CA 3.34Å; Q510-R542 PolarHBondContact O-N 3.39Å; Q510-E562 PolarHBondContact NE2-OE2 2.91Å
511Q91.8Very high90.4Very high0 Ų061.9 Ų61.90%035%0.345CS..EExtended strand (participates in β ladder)trans-85.7126.5-178.6-62.3179.234.500111.8K497 I500 I506 P507 P508 D509 L539K497-Q511 HydrophobicContact CD-CB 4.32Å; K497-Q511 WeakPolarHBondContact CE-O 3.16Å; K497-Q511 HydrophobicContact CG-CB 4.06Å; K497-Q511 PolarHBondContact NZ-O 3.3Å; K497-Q511 PolarHBondContact O-NE2 3.01Å; K497-Q511 PolarHBondContact O-OE1 3.19Å; I500-Q511 VanDerWaalsContact CD1-OE1 3.3Å; I506-Q511 HydrophobicContact CB-CG 4.33Å; I506-Q511 HydrophobicContact CG2-CG 3.64Å; I506-Q511 PolarHBondContact O-NE2 2.92Å; P507-Q511 WeakPolarHBondContact O-CG 3.39Å; P507-Q511 PolarHBondContact O-N 3.35Å; P508-Q511 PolarHBondContact O-N 2.93Å; D509-Q511 VanDerWaalsContact C-N 3.34Å; Q511-L539 HydrophobicContact CB-CD1 3.76Å; Q511-L539 HydrophobicContact CG-CD1 3.95Å
512R93.6Very high90.5Very high103 Ų10362.6 Ų62.639%0.38935%0.35SS..EExtended strand (participates in β ladder)trans-117.1108.6166.7-165.2-176.1-161.3-172.82.7109.3Q519 V540 R542R512-Q519 HydrophobicContact CG-CG 3.99Å; R512-V540 WeakPolarHBondContact CA-O 3.12Å; R512-V540 HydrophobicContact CB-CB 4.33Å; R512-V540 WeakPolarHBondContact CB-O 3.4Å; R512-V540 PolarHBondContact N-O 3.01Å; R512-V540 PolarHBondContact O-N 3.47Å; R512-R542 HydrophobicContact CB-CG 4.26Å
513L96.4Very high90.8Very high1 Ų159.9 Ų59.91%0.00535%0.354CS..EExtended strand (participates in β ladder)trans-91.8136.9177.5-64.9175.9000111.1V475 I493 V496 K497 I500 L520 L537 H538 L539V475-L513 HydrophobicContact CG1-CD2 4.09Å; I493-L513 HydrophobicContact CG2-CD1 4.27Å; V496-L513 HydrophobicContact CB-CD1 4.44Å; V496-L513 HydrophobicContact CG1-CD1 3.84Å; K497-L513 HydrophobicContact CG-CD1 3.9Å; K497-L513 HydrophobicContact CG-CG 4.48Å; I500-L513 HydrophobicContact CD1-CD1 3.99Å; I500-L513 HydrophobicContact CD1-CD2 3.66Å; I500-L513 HydrophobicContact CD1-CG 4.33Å; L513-L520 HydrophobicContact CB-CB 4.28Å; L513-L520 HydrophobicContact CB-CD1 4Å; L513-L520 HydrophobicContact CB-CG 4.33Å; L513-L520 PolarHBondContact O-N 2.9Å; L513-L537 HydrophobicContact CD1-CD2 4.42Å; L513-H538 WeakPolarHBondContact CA-O 3.43Å; L513-L539 HydrophobicContact CD2-CB 4.17Å; L513-L539 HydrophobicContact CD2-CD1 3.9Å
514I96.2Very high91.2Very high44 Ų4459.7 Ų59.723%0.22635%0.35CS..EExtended strand (participates in β ladder)trans-130.5132.7-178.4-58.5168.4000109.1K518 L537 H538 V540I514-K518 CarbonylContact C-O 3.46Å; I514-K518 VanDerWaalsContact CA-O 3.28Å; I514-K518 WeakPolarHBondContact CA-O 3.49Å; I514-L537 CarbonylContact O-C 3.47Å; I514-L537 WeakPolarHBondContact O-CA 3.42Å; I514-H538 HydrophobicContact CB-CB 4.33Å; I514-H538 PolarHBondContact N-O 2.95Å; I514-H538 PolarHBondContact O-N 2.98Å; I514-V540 HydrophobicContact CD1-CG2 3.86Å
515F97.2Very high91.6Very high41 Ų4157.9 Ų57.918%0.1834%0.343CS..EExtended strand (participates in β ladder)trans-137.7136.3173.2-176.9-112.9000109.9G517 K518 L520 I531 T536 L537F515-G517 PolarHBondContact O-N 3Å; F515-G517 VanDerWaalsContact O-N 3.1Å; F515-K518 PolarHBondContact N-O 2.92Å; F515-K518 PolarHBondContact O-N 3.38Å; F515-L520 HydrophobicContact CB-CD1 4.15Å; F515-L520 HydrophobicContact CB-CD2 3.96Å; F515-L520 HydrophobicContact CB-CG 4.35Å; F515-I531 HydrophobicContact CB-CD1 4.33Å; F515-I531 HydrophobicContact CD1-CD1 4.1Å; F515-I531 HydrophobicContact CD1-CG1 3.49Å; F515-I531 VanDerWaalsContact CD1-CG1 3.49Å; F515-I531 HydrophobicContact CD2-CG1 4.36Å; F515-I531 HydrophobicContact CE1-CG1 3.59Å; F515-I531 HydrophobicContact CE2-CG1 4.45Å; F515-I531 HydrophobicContact CG-CD1 4.16Å; F515-I531 HydrophobicContact CG-CG1 3.9Å; F515-I531 HydrophobicContact CZ-CG1 4.09Å; F515-T536 WeakPolarHBondContact CD2-O 3.47Å; F515-L537 HydrophobicContact CB-CG 4.3Å; F515-L537 HydrophobicContact CD2-CD1 4.24Å; F515-L537 HydrophobicContact CD2-CG 4.36Å
516A93.9Very high92.2Very high90 Ų9055.1 Ų55.174%0.74431%0.314SS*.THydrogen-bonded Turntrans47.241.3-179.400000113.9K518A516-K518 PolarHBondContact O-N 2.69Å
517G90.6Very high92.7Very high78 Ų7857 Ų5780%0.80433%0.33SS*.THydrogen-bonded Turntrans75.6-2-179.200000115.8F515F515-G517 PolarHBondContact O-N 3Å; F515-G517 VanDerWaalsContact O-N 3.1Å
518K94Very high93.3Very high141 Ų14160.2 Ų60.261%0.61335%0.346SS*.EExtended strand (participates in β ladder)trans-104.2138.2178.1-67-175.7179.9179.40111.3I514 F515 A516I514-K518 CarbonylContact C-O 3.46Å; I514-K518 VanDerWaalsContact CA-O 3.28Å; I514-K518 WeakPolarHBondContact CA-O 3.49Å; F515-K518 PolarHBondContact N-O 2.92Å; F515-K518 PolarHBondContact O-N 3.38Å; A516-K518 PolarHBondContact O-N 2.69Å
519Q94.3Very high93.7Very high78 Ų7861 Ų6136%0.36435%0.346SS..EExtended strand (participates in β ladder)trans-71.3137166.5-176.5-171.4-37.500109.3R512 R542R512-Q519 HydrophobicContact CG-CG 3.99Å; Q519-R542 VanDerWaalsContact NE2-NH2 3.19Å
520L96.6Very high94.2Very high4 Ų462.5 Ų62.52%0.02135%0.354CS..PPolyproline II helixtrans-85.7140178.4-54.6-175000111.2I493 L513 F515 Y529 I531 L537I493-L520 HydrophobicContact CD1-CB 3.9Å; I493-L520 HydrophobicContact CD1-CD1 3.63Å; I493-L520 HydrophobicContact CD1-CG 4.29Å; I493-L520 HydrophobicContact CG1-CB 3.9Å; I493-L520 HydrophobicContact CG2-CB 3.86Å; L513-L520 HydrophobicContact CB-CB 4.28Å; L513-L520 HydrophobicContact CB-CD1 4Å; L513-L520 HydrophobicContact CB-CG 4.33Å; L513-L520 PolarHBondContact O-N 2.9Å; F515-L520 HydrophobicContact CB-CD1 4.15Å; F515-L520 HydrophobicContact CB-CD2 3.96Å; F515-L520 HydrophobicContact CB-CG 4.35Å; L520-Y529 HydrophobicContact CB-CE2 4.26Å; L520-Y529 HydrophobicContact CD2-CD1 3.66Å; L520-Y529 HydrophobicContact CD2-CD2 3.68Å; L520-Y529 HydrophobicContact CD2-CE1 3.76Å; L520-Y529 HydrophobicContact CD2-CE2 3.74Å; L520-Y529 HydrophobicContact CD2-CG 3.62Å; L520-I531 HydrophobicContact CD1-CD1 3.93Å; L520-L537 HydrophobicContact CD1-CD2 3.49Å; L520-L537 VanDerWaalsContact CD1-CD2 3.49Å; L520-L537 HydrophobicContact CD1-CG 4.21Å
521E94.9Very high94.7Very high107 Ų10761.2 Ų61.250%0.535%0.348SS..PPolyproline II helixtrans-99.1134.2-179.3-67170.3-178.400110.8I493 G523 R524 Y529I493-E521 VanDerWaalsContact CB-O 3.28Å; I493-E521 WeakPolarHBondContact CB-O 3.43Å; I493-E521 VanDerWaalsContact CG1-O 3.28Å; I493-E521 WeakPolarHBondContact CG1-O 3.38Å; E521-G523 VanDerWaalsContact C-N 3.29Å; E521-G523 PolarHBondContact O-N 2.69Å; E521-R524 HydrophobicContact CB-CG 4.34Å; E521-R524 PolarHBondContact O-N 3.04Å; E521-R524 VanDerWaalsContact O-N 3.1Å; E521-R524 IonicContact OE2-CZ 3.92Å; E521-R524 IonicContact OE2-NE 3.92Å; E521-R524 PolarHBondContact OE2-NE 2.71Å; E521-R524 VanDerWaalsContact OE2-NE 3.1Å; E521-R524 IonicContact OE2-NH2 2.74Å; E521-Y529 WeakPolarHBondContact CB-OH 3.49Å; E521-Y529 PolarHBondContact N-OH 2.7Å
522D91.1Very high94.8Very high68 Ų6866.5 Ų66.536%0.36437%0.373SS..THydrogen-bonded Turntrans-56.1-37.9-171.4-68.9-20000113.8I493 E494 K497 R524I493-D522 PolarHBondContact N-O 3.43Å; E494-D522 HydrophobicContact CB-CB 4.22Å; E494-D522 PolarHBondContact N-O 3.35Å; K497-D522 WeakPolarHBondContact CD-OD1 3.43Å; K497-D522 WeakPolarHBondContact CE-OD1 3.35Å; K497-D522 IonicContact NZ-OD1 2.74Å; K497-D522 PolarHBondContact NZ-OD1 2.98Å; K497-D522 IonicContact NZ-OD2 2.62Å; K497-D522 PolarHBondContact NZ-OD2 3.22Å; D522-R524 VanDerWaalsContact C-N 3.33Å; D522-R524 PolarHBondContact O-N 2.76Å
523G91.3Very high94.8Very high75 Ų7567.7 Ų67.777%0.77338%0.381SS*.THydrogen-bonded Turntrans-82.63.8-178.500000116.2E521E521-G523 VanDerWaalsContact C-N 3.29Å; E521-G523 PolarHBondContact O-N 2.69Å
524R95.5Very high94.7Very high116 Ų11673.7 Ų73.744%0.43841%0.409SS..SBendtrans-103.2159.1176.2-68.9-157.9-172.7-126.4-1.2111.5T492 I493 E521 D522 D528 Y529T492-R524 CarbonylContact C-O 3.47Å; T492-R524 VanDerWaalsContact CA-O 3.24Å; T492-R524 WeakPolarHBondContact CA-O 3.49Å; I493-R524 WeakPolarHBondContact CG1-O 3.49Å; I493-R524 PolarHBondContact N-O 3.24Å; E521-R524 HydrophobicContact CB-CG 4.34Å; E521-R524 PolarHBondContact O-N 3.04Å; E521-R524 VanDerWaalsContact O-N 3.1Å; E521-R524 IonicContact OE2-CZ 3.92Å; E521-R524 IonicContact OE2-NE 3.92Å; E521-R524 PolarHBondContact OE2-NE 2.71Å; E521-R524 VanDerWaalsContact OE2-NE 3.1Å; E521-R524 IonicContact OE2-NH2 2.74Å; D522-R524 VanDerWaalsContact C-N 3.33Å; D522-R524 PolarHBondContact O-N 2.76Å; R524-D528 HydrophobicContact CB-CB 4.3Å; R524-Y529 HydrophobicContact CB-CD2 4.28Å; R524-Y529 HydrophobicContact CB-CE2 3.6Å; R524-Y529 HydrophobicContact CG-CE2 4.3Å
525T96.2Very high94.8Very high28 Ų2872.5 Ų72.517%0.17240%0.404CS..BIsolated β-bridgetrans-92.6166.4178.167.80000112.5S490 D491 S527 D528S490-T525 WeakPolarHBondContact O-CG2 3.5Å; D491-T525 CarbonylContact O-C 3.58Å; D491-T525 WeakPolarHBondContact O-CA 3.21Å; T525-S527 VanDerWaalsContact C-N 3.26Å; T525-S527 PolarHBondContact O-N 2.88Å; T525-S527 PolarHBondContact OG1-N 2.8Å; T525-S527 PolarHBondContact OG1-OG 3.42Å; T525-D528 PolarHBondContact N-OD2 3.22Å; T525-D528 PolarHBondContact O-N 3.45Å; T525-D528 PolarHBondContact OG1-N 2.88Å; T525-D528 PolarHBondContact OG1-OD2 3.25Å
526L96Very high94.7Very high0 Ų073 Ų730%041%0.411CS..THydrogen-bonded Turntrans-58.9-39.1169.5-68.7-177.8000112.1I473 V487 D491 I493 V496 D528 Y529 N530 I531I473-L526 HydrophobicContact CD1-CD1 4.2Å; I473-L526 HydrophobicContact CD1-CD2 4.25Å; V487-L526 HydrophobicContact CB-CD1 3.56Å; V487-L526 HydrophobicContact CG1-CD1 4.07Å; V487-L526 HydrophobicContact CG2-CD1 3.49Å; V487-L526 VanDerWaalsContact CG2-CD1 3.49Å; D491-L526 HydrophobicContact CB-CD1 4.27Å; D491-L526 HydrophobicContact CB-CG 4.48Å; D491-L526 PolarHBondContact O-N 3.01Å; I493-L526 HydrophobicContact CD1-CD2 4.02Å; V496-L526 HydrophobicContact CG2-CD1 4.17Å; V496-L526 HydrophobicContact CG2-CD2 3.97Å; V496-L526 HydrophobicContact CG2-CG 4.13Å; L526-D528 PolarHBondContact O-N 2.82Å; L526-Y529 PolarHBondContact O-N 3.23Å; L526-N530 PolarHBondContact O-N 3.25Å; L526-I531 HydrophobicContact CB-CB 4.23Å; L526-I531 HydrophobicContact CD2-CB 4.19Å; L526-I531 HydrophobicContact CD2-CD1 3.57Å; L526-I531 HydrophobicContact CD2-CG1 4.46Å; L526-I531 HydrophobicContact CD2-CG2 4.12Å; L526-I531 WeakPolarHBondContact O-CB 3.49Å; L526-I531 PolarHBondContact O-N 2.87Å
527S95.5Very high94.9Very high66 Ų6668.7 Ų68.746%0.46238%0.375SS..G310 helixtrans-64-36.2178.378.40000113P489 T525 Y529 N530P489-S527 WeakPolarHBondContact O-CB 3.42Å; P489-S527 PolarHBondContact O-N 3.29Å; T525-S527 VanDerWaalsContact C-N 3.26Å; T525-S527 PolarHBondContact O-N 2.88Å; T525-S527 PolarHBondContact OG1-N 2.8Å; T525-S527 PolarHBondContact OG1-OG 3.42Å; S527-Y529 PolarHBondContact O-N 3.44Å; S527-N530 WeakPolarHBondContact O-CA 3.42Å; S527-N530 PolarHBondContact O-N 3.36Å
528D95.9Very high95.2Very high92 Ų9269.6 Ų69.649%0.49236%0.358SS..G310 helixtrans-61.6-30.5178.4-67.3-45.4000112.5R524 T525 L526R524-D528 HydrophobicContact CB-CB 4.3Å; T525-D528 PolarHBondContact N-OD2 3.22Å; T525-D528 PolarHBondContact O-N 3.45Å; T525-D528 PolarHBondContact OG1-N 2.88Å; T525-D528 PolarHBondContact OG1-OD2 3.25Å; L526-D528 PolarHBondContact O-N 2.82Å
529Y96.2Very high95.3Very high40 Ų4063.1 Ų63.116%0.15733%0.33CS..G310 helixtrans-93.73.9175.4-71.7-74.1000113.5I493 L520 E521 R524 L526 S527 I531I493-Y529 HydrophobicContact CD1-CD2 4.46Å; I493-Y529 HydrophobicContact CG1-CE2 4.23Å; L520-Y529 HydrophobicContact CB-CE2 4.26Å; L520-Y529 HydrophobicContact CD2-CD1 3.66Å; L520-Y529 HydrophobicContact CD2-CD2 3.68Å; L520-Y529 HydrophobicContact CD2-CE1 3.76Å; L520-Y529 HydrophobicContact CD2-CE2 3.74Å; L520-Y529 HydrophobicContact CD2-CG 3.62Å; E521-Y529 WeakPolarHBondContact CB-OH 3.49Å; E521-Y529 PolarHBondContact N-OH 2.7Å; R524-Y529 HydrophobicContact CB-CD2 4.28Å; R524-Y529 HydrophobicContact CB-CE2 3.6Å; R524-Y529 HydrophobicContact CG-CE2 4.3Å; L526-Y529 PolarHBondContact O-N 3.23Å; S527-Y529 PolarHBondContact O-N 3.44Å; Y529-I531 PolarHBondContact O-N 2.78Å
530N95.6Very high95.1Very high110 Ų11061.3 Ų61.359%0.58832%0.324SS*.THydrogen-bonded Turntrans54.138.2-175.2-163.125.5000112.3L526 S527 Q532L526-N530 PolarHBondContact O-N 3.25Å; S527-N530 WeakPolarHBondContact O-CA 3.42Å; S527-N530 PolarHBondContact O-N 3.36Å; N530-Q532 PolarHBondContact O-N 3.39Å; N530-Q532 PolarHBondContact OD1-NE2 3.03Å
531I95.1Very high94.6Very high3 Ų365.2 Ų65.22%0.01535%0.345CS..PPolyproline II helixtrans-75.2120.6174.7-66.4168.4000107.1M471 I473 F515 L520 L526 Y529 L537M471-I531 HydrophobicContact CE-CG2 4.39Å; M471-I531 WeakPolarHBondContact CE-O 3.44Å; I473-I531 HydrophobicContact CG2-CG2 3.88Å; F515-I531 HydrophobicContact CB-CD1 4.33Å; F515-I531 HydrophobicContact CD1-CD1 4.1Å; F515-I531 HydrophobicContact CD1-CG1 3.49Å; F515-I531 VanDerWaalsContact CD1-CG1 3.49Å; F515-I531 HydrophobicContact CD2-CG1 4.36Å; F515-I531 HydrophobicContact CE1-CG1 3.59Å; F515-I531 HydrophobicContact CE2-CG1 4.45Å; F515-I531 HydrophobicContact CG-CD1 4.16Å; F515-I531 HydrophobicContact CG-CG1 3.9Å; F515-I531 HydrophobicContact CZ-CG1 4.09Å; L520-I531 HydrophobicContact CD1-CD1 3.93Å; L526-I531 HydrophobicContact CB-CB 4.23Å; L526-I531 HydrophobicContact CD2-CB 4.19Å; L526-I531 HydrophobicContact CD2-CD1 3.57Å; L526-I531 HydrophobicContact CD2-CG1 4.46Å; L526-I531 HydrophobicContact CD2-CG2 4.12Å; L526-I531 WeakPolarHBondContact O-CB 3.49Å; L526-I531 PolarHBondContact O-N 2.87Å; Y529-I531 PolarHBondContact O-N 2.78Å; I531-L537 HydrophobicContact CD1-CD1 4.31Å; I531-L537 HydrophobicContact CD1-CD2 4.32Å; I531-L537 HydrophobicContact CD1-CG 4.48Å; I531-L537 HydrophobicContact CG2-CD1 4.06Å
532Q94.7Very high93.9Very high111 Ų11165.1 Ų65.152%0.51934%0.34SS..PPolyproline II helixtrans-103.3168.9-176.2-64.2-63.5-28.300111.3N530 E534 S535N530-Q532 PolarHBondContact O-N 3.39Å; N530-Q532 PolarHBondContact OD1-NE2 3.03Å; Q532-E534 PolarHBondContact O-N 3.16Å; Q532-S535 PolarHBondContact N-OG 3.32Å; Q532-S535 WeakPolarHBondContact O-CB 2.86Å; Q532-S535 PolarHBondContact O-N 3.03Å; Q532-S535 PolarHBondContact O-OG 3.41Å
533K93.5Very high92.4Very high128 Ų12870.3 Ų70.356%0.55737%0.367SS*.THydrogen-bonded Turntrans-51.8137.7170.9-173172.3178.7176.40110.2M471 S535M471-K533 HydrophobicContact CG-CB 4.07Å; M471-K533 HydrophobicContact CG-CG 4.46Å; K533-S535 PolarHBondContact O-N 3.18Å
534E94.5Very high90.7Very high128 Ų12877.2 Ų77.260%0.59837%0.37SS*.THydrogen-bonded Turntrans65.211.3-176.5-65.4170.3-169.700115.6Q472 F474 Q532Q472-E534 WeakPolarHBondContact O-CA 3.41Å; Q472-E534 PolarHBondContact O-N 3.33Å; F474-E534 WeakPolarHBondContact CD2-O 3.31Å; F474-E534 HydrophobicContact CE2-CB 3.87Å; F474-E534 HydrophobicContact CE2-CG 3.94Å; F474-E534 HydrophobicContact CZ-CG 4.46Å; Q532-E534 PolarHBondContact O-N 3.16Å
535S97.2Very high88.9Confident19 Ų1974.7 Ų74.713%0.13338%0.379CS..  trans-61.4146172.1-67.80000111.8F474 Q532 K533F474-S535 PolarHBondContact N-O 3.04Å; Q532-S535 PolarHBondContact N-OG 3.32Å; Q532-S535 WeakPolarHBondContact O-CB 2.86Å; Q532-S535 PolarHBondContact O-N 3.03Å; Q532-S535 PolarHBondContact O-OG 3.41Å; K533-S535 PolarHBondContact O-N 3.18Å
536T97.1Very high87.3Confident51 Ų5173.9 Ų73.931%0.31338%0.377SS..EExtended strand (participates in β ladder)trans-108.8116177.1-580000111.3F474 K476 F515F474-T536 HydrophobicContact CB-CG2 4.45Å; F474-T536 CarbonylContact O-C 3.52Å; F474-T536 VanDerWaalsContact O-CA 3.3Å; F474-T536 WeakPolarHBondContact O-CA 3.06Å; K476-T536 HydrophobicContact CB-CG2 4.32Å; K476-T536 HydrophobicContact CD-CG2 3.91Å; K476-T536 HydrophobicContact CG-CG2 3.87Å; F515-T536 WeakPolarHBondContact CD2-O 3.47Å
537L97.5Very high86.2Confident0 Ų078.9 Ų78.90%040%0.401CS..EExtended strand (participates in β ladder)trans-92.3153.4169-71.269000109.4I473 F474 V475 K476 L513 I514 F515 L520 I531I473-L537 HydrophobicContact CB-CD1 4.37Å; I473-L537 HydrophobicContact CD1-CD1 3.99Å; I473-L537 HydrophobicContact CD1-CD2 4.34Å; F474-L537 PolarHBondContact O-N 3.43Å; V475-L537 CarbonylContact C-O 3.42Å; V475-L537 WeakPolarHBondContact CA-O 3.5Å; V475-L537 HydrophobicContact CG2-CB 4.37Å; K476-L537 PolarHBondContact N-O 3.18Å; L513-L537 HydrophobicContact CD1-CD2 4.42Å; I514-L537 CarbonylContact O-C 3.47Å; I514-L537 WeakPolarHBondContact O-CA 3.42Å; F515-L537 HydrophobicContact CB-CG 4.3Å; F515-L537 HydrophobicContact CD2-CD1 4.24Å; F515-L537 HydrophobicContact CD2-CG 4.36Å; L520-L537 HydrophobicContact CD1-CD2 3.49Å; L520-L537 VanDerWaalsContact CD1-CD2 3.49Å; L520-L537 HydrophobicContact CD1-CG 4.21Å; I531-L537 HydrophobicContact CD1-CD1 4.31Å; I531-L537 HydrophobicContact CD1-CD2 4.32Å; I531-L537 HydrophobicContact CD1-CG 4.48Å; I531-L537 HydrophobicContact CG2-CD1 4.06Å
538H96.9Very high85.3Confident97 Ų9779.8 Ų79.845%0.44940%0.398SS..EExtended strand (participates in β ladder)trans-107.5129.1172.6-66.773.6000109.7K476 L513 I514K476-H538 WeakPolarHBondContact O-CA 3.42Å; L513-H538 WeakPolarHBondContact CA-O 3.43Å; I514-H538 HydrophobicContact CB-CB 4.33Å; I514-H538 PolarHBondContact N-O 2.95Å; I514-H538 PolarHBondContact O-N 2.98Å
539L95Very high84.5Confident4 Ų476.4 Ų76.42%0.02138%0.38CS..EExtended strand (participates in β ladder)trans-99120174.2175.962.7000110V475 K476 T477 I500 I506 Q511 L513 L541V475-L539 HydrophobicContact CG1-CB 3.55Å; V475-L539 HydrophobicContact CG1-CD2 4.43Å; K476-L539 PolarHBondContact O-N 3.33Å; T477-L539 HydrophobicContact CG2-CD2 4.48Å; I500-L539 HydrophobicContact CG2-CD2 4Å; I506-L539 HydrophobicContact CD1-CD2 3.89Å; Q511-L539 HydrophobicContact CB-CD1 3.76Å; Q511-L539 HydrophobicContact CG-CD1 3.95Å; L513-L539 HydrophobicContact CD2-CB 4.17Å; L513-L539 HydrophobicContact CD2-CD1 3.9Å; L539-L541 HydrophobicContact CD1-CD2 4.49Å; L539-L541 HydrophobicContact CD2-CD2 4.45Å; L539-L541 HydrophobicContact CG-CD2 4.38Å
540V91.2Very high83.9Confident40 Ų4079.9 Ų79.924%0.24240%0.396CS..EExtended strand (participates in β ladder)trans-113.6128.7170.9178.20000108.2L478 R512 I514L478-V540 HydrophobicContact CD1-CG1 4.21Å; L478-V540 HydrophobicContact CD1-CG2 4.46Å; L478-V540 HydrophobicContact CD2-CG2 4.16Å; L478-V540 HydrophobicContact CG-CG2 4.37Å; R512-V540 WeakPolarHBondContact CA-O 3.12Å; R512-V540 HydrophobicContact CB-CB 4.33Å; R512-V540 WeakPolarHBondContact CB-O 3.4Å; R512-V540 PolarHBondContact N-O 3.01Å; R512-V540 PolarHBondContact O-N 3.47Å; I514-V540 HydrophobicContact CD1-CG2 3.86Å
541L86.3Confident83.2Confident86 Ų8675.6 Ų75.645%0.4537%0.374SS..EExtended strand (participates in β ladder)trans-80.7133.6176.6-60.2-178.6000110.3I506 Q510 L539I506-L541 HydrophobicContact CD1-CD2 4.2Å; I506-L541 HydrophobicContact CG2-CD2 3.49Å; I506-L541 VanDerWaalsContact CG2-CD2 3.49Å; Q510-L541 CarbonylContact O-C 3.55Å; Q510-L541 WeakPolarHBondContact O-CA 3.34Å; L539-L541 HydrophobicContact CD1-CD2 4.49Å; L539-L541 HydrophobicContact CD2-CD2 4.45Å; L539-L541 HydrophobicContact CG-CD2 4.38Å
542R79.1Confident82.4Confident105 Ų10583 Ų8340%0.39641%0.406SS..  trans-82.2123.8169.8-69.9176.1164.1166.8-3.1108.6Q510 R512 Q519 R544Q510-R542 PolarHBondContact O-N 3.39Å; R512-R542 HydrophobicContact CB-CG 4.26Å; Q519-R542 VanDerWaalsContact NE2-NH2 3.19Å; R542-R544 PolarHBondContact O-N 3.3Å; R542-R544 VanDerWaalsContact O-N 3.11Å
543L60.3Low81.6Confident177 Ų17779.5 Ų79.593%0.92739%0.392SS*.  trans-79.424.4-178.4-67.6171.8000114.4
544R55.3Low80.7Confident221 Ų22182.5 Ų82.583%0.83441%0.413SS*.SBendtrans-104.1115.3175.9-73.6-170.2-178.3178.10.9108.6R542 G546R542-R544 PolarHBondContact O-N 3.3Å; R542-R544 VanDerWaalsContact O-N 3.11Å; R544-G546 PolarHBondContact O-N 3.31Å
545G57.5Low79.8Confident62 Ų6282.5 Ų82.564%0.63942%0.422SS*.PPolyproline II helixtrans-52.9131.2-172.800000112
546G62.4Low78.7Confident12 Ų1284 Ų8412%0.12444%0.441CS..PPolyproline II helixtrans-63.3170.6174.100000110.7R544 Q548 E562R544-G546 PolarHBondContact O-N 3.31Å; G546-Q548 PolarHBondContact O-N 2.98Å; G546-Q548 VanDerWaalsContact O-N 3.13Å; G546-E562 PolarHBondContact N-OE1 2.88Å
547M73Confident77.9Confident104 Ų10486.5 Ų86.551%0.51245%0.447SS..PPolyproline II helixtrans-56.9123.2173.9176.7178.4-178.300109E562 V563 P565M547-E562 CarbonylContact O-C 3.6Å; M547-E562 WeakPolarHBondContact O-CA 3.34Å; M547-V563 WeakPolarHBondContact CB-O 3.34Å; M547-V563 HydrophobicContact CG-CG2 4.04Å; M547-V563 PolarHBondContact O-N 2.85Å; M547-V563 VanDerWaalsContact O-O 3.09Å; M547-V563 HydrophobicContact SD-CG2 4.48Å; M547-P565 HydrophobicContact SD-CG 4.49Å
548Q76.5Confident77.1Confident85 Ų8589.6 Ų89.640%0.39747%0.466SS..EExtended strand (participates in β ladder)trans-111.9137.2-177.9-79.617222.400110.3G546 T560 L561 E562G546-Q548 PolarHBondContact O-N 2.98Å; G546-Q548 VanDerWaalsContact O-N 3.13Å; Q548-T560 HydrophobicContact CB-CG2 4.02Å; Q548-T560 HydrophobicContact CG-CG2 3.89Å; Q548-L561 CarbonylContact C-O 3.57Å; Q548-L561 VanDerWaalsContact CA-O 3.23Å; Q548-L561 WeakPolarHBondContact CA-O 3.32Å; Q548-E562 HydrophobicContact CG-CG 3.82Å; Q548-E562 PolarHBondContact NE2-OE1 2.71Å
549I80.5Confident76.3Confident21 Ų2185.3 Ų85.311%0.10845%0.447CS..EExtended strand (participates in β ladder)trans-112146.4165.162.1171.1000109.6L561 V563 V572 M602I549-L561 HydrophobicContact CD1-CD1 4.16Å; I549-L561 HydrophobicContact CG1-CB 3.86Å; I549-L561 HydrophobicContact CG1-CD1 4.25Å; I549-L561 PolarHBondContact N-O 2.82Å; I549-L561 PolarHBondContact O-N 3.14Å; I549-V563 HydrophobicContact CB-CG2 4.37Å; I549-V563 HydrophobicContact CD1-CG1 3.66Å; I549-V563 HydrophobicContact CD1-CG2 4.47Å; I549-V563 HydrophobicContact CG1-CG1 3.72Å; I549-V563 HydrophobicContact CG1-CG2 4.1Å; I549-V563 HydrophobicContact CG2-CG2 3.63Å; I549-V572 HydrophobicContact CD1-CG1 3.72Å; I549-V572 HydrophobicContact CD1-CG2 4.06Å; I549-M602 HydrophobicContact CD1-SD 4.37Å
550F81.9Confident75.7Confident114 Ų11487.5 Ų87.550%0.546%0.46SS..EExtended strand (participates in β ladder)trans-108.5117.2178.9-60.1-85.5000109.3T558 I559 T560F550-T558 HydrophobicContact CB-CG2 3.9Å; F550-T558 HydrophobicContact CD1-CG2 3.98Å; F550-T558 HydrophobicContact CG-CG2 4.39Å; F550-I559 CarbonylContact C-O 3.58Å; F550-I559 WeakPolarHBondContact CA-O 3.29Å; F550-T560 HydrophobicContact CD1-CG2 4.04Å; F550-T560 WeakPolarHBondContact CD1-OG1 3.4Å; F550-T560 HydrophobicContact CE1-CG2 3.63Å; F550-T560 WeakPolarHBondContact CE1-OG1 3.34Å; F550-T560 HydrophobicContact CZ-CG2 4.24Å
551V81.7Confident75.2Confident19 Ų1985.7 Ų85.712%0.11545%0.449CS..EExtended strand (participates in β ladder)trans-101.1111.7176.4-178.80000108.4I559 L561 I576 L589V551-I559 HydrophobicContact CB-CB 4.41Å; V551-I559 PolarHBondContact N-O 2.91Å; V551-I559 PolarHBondContact O-N 3.25Å; V551-L561 HydrophobicContact CB-CD1 4.49Å; V551-L561 HydrophobicContact CG2-CD1 3.52Å; V551-L561 HydrophobicContact CG2-CG 4.36Å; V551-I576 HydrophobicContact CG1-CD1 4.14Å; V551-I576 HydrophobicContact CG2-CD1 4.15Å; V551-L589 HydrophobicContact CG1-CD2 4.12Å
552K77.6Confident74.7Confident158 Ų15884.5 Ų84.569%0.68744%0.441SS*.EExtended strand (participates in β ladder)trans-85.8125.8170.8-90.7-177.8175.4-179.90110.3K557 T558K552-K557 WeakPolarHBondContact CA-O 3.39Å; K552-T558 WeakPolarHBondContact CE-OG1 3.23Å; K552-T558 HydrophobicContact CG-CG2 4.33Å; K552-T558 WeakPolarHBondContact CG-OG1 3.41Å
553T78.1Confident74.7Confident39 Ų3980 Ų8024%0.23943%0.426CS..  trans-77162.417070.10000110.7T555 G556 K557 I559T553-T555 PolarHBondContact O-N 3.09Å; T553-T555 VanDerWaalsContact O-N 3.17Å; T553-T555 PolarHBondContact OG1-N 3.49Å; T553-T555 PolarHBondContact OG1-OG1 3.07Å; T553-G556 PolarHBondContact O-N 3.09Å; T553-K557 HydrophobicContact CG2-CB 4.46Å; T553-K557 PolarHBondContact N-O 3.38Å; T553-K557 WeakPolarHBondContact OG1-CB 3.46Å; T553-K557 PolarHBondContact OG1-N 2.78Å; T553-K557 PolarHBondContact OG1-O 2.85Å; T553-I559 HydrophobicContact CG2-CD1 3.49Å; T553-I559 VanDerWaalsContact CG2-CD1 3.49Å; T553-I559 HydrophobicContact CG2-CG1 4.29Å
554L75Confident75.3Confident190 Ų19074.1 Ų74.1100%0.99539%0.394SS*.THydrogen-bonded Turntrans-62.2-20174.6-66.1174.9000113.4G556L554-G556 PolarHBondContact O-N 2.99Å
555T76Confident76.1Confident128 Ų12869.5 Ų69.579%0.78539%0.392SS*.THydrogen-bonded Turntrans-79.9-4.2175.1690000113.2T553T553-T555 PolarHBondContact O-N 3.09Å; T553-T555 VanDerWaalsContact O-N 3.17Å; T553-T555 PolarHBondContact OG1-N 3.49Å; T553-T555 PolarHBondContact OG1-OG1 3.07Å
556G73.4Confident76.9Confident51 Ų5170.7 Ų70.753%0.52639%0.391SS..SBendtrans89.8-10.1-176.700000114.6T553 L554 T558T553-G556 PolarHBondContact O-N 3.09Å; L554-G556 PolarHBondContact O-N 2.99Å; G556-T558 PolarHBondContact O-N 3.23Å
557K80.5Confident77.6Confident103 Ų10371.3 Ų71.345%0.44839%0.391SS..  trans-63.1130.4174-177-178.8174.3-170.40110.5K552 T553 E580K552-K557 WeakPolarHBondContact CA-O 3.39Å; T553-K557 HydrophobicContact CG2-CB 4.46Å; T553-K557 PolarHBondContact N-O 3.38Å; T553-K557 WeakPolarHBondContact OG1-CB 3.46Å; T553-K557 PolarHBondContact OG1-N 2.78Å; T553-K557 PolarHBondContact OG1-O 2.85Å; K557-E580 WeakPolarHBondContact CE-OE1 3.29Å; K557-E580 IonicContact NZ-OE1 2.72Å; K557-E580 PolarHBondContact NZ-OE1 2.83Å; K557-E580 IonicContact NZ-OE2 2.66Å; K557-E580 PolarHBondContact NZ-OE2 2.8Å
558T81Confident78Confident65 Ų6569.6 Ų69.640%0.39939%0.386SS..EExtended strand (participates in β ladder)trans-98.1127.2173.9-53.90000109.5F550 K552 G556F550-T558 HydrophobicContact CB-CG2 3.9Å; F550-T558 HydrophobicContact CD1-CG2 3.98Å; F550-T558 HydrophobicContact CG-CG2 4.39Å; K552-T558 WeakPolarHBondContact CE-OG1 3.23Å; K552-T558 HydrophobicContact CG-CG2 4.33Å; K552-T558 WeakPolarHBondContact CG-OG1 3.41Å; G556-T558 PolarHBondContact O-N 3.23Å
559I80Confident78.2Confident8 Ų866.5 Ų66.54%0.04137%0.372CS..EExtended strand (participates in β ladder)trans-108.7120.6176.4-56152.4000107.2F550 V551 T553 L561 K579 E580F550-I559 CarbonylContact C-O 3.58Å; F550-I559 WeakPolarHBondContact CA-O 3.29Å; V551-I559 HydrophobicContact CB-CB 4.41Å; V551-I559 PolarHBondContact N-O 2.91Å; V551-I559 PolarHBondContact O-N 3.25Å; T553-I559 HydrophobicContact CG2-CD1 3.49Å; T553-I559 VanDerWaalsContact CG2-CD1 3.49Å; T553-I559 HydrophobicContact CG2-CG1 4.29Å; I559-L561 HydrophobicContact CG2-CD2 3.96Å; I559-L561 HydrophobicContact CG2-CG 4.32Å; I559-K579 HydrophobicContact CG2-CB 4.47Å; I559-K579 HydrophobicContact CG2-CD 4.05Å; I559-E580 HydrophobicContact CD1-CG 3.52Å; I559-E580 HydrophobicContact CG1-CG 4Å
560T82.7Confident78.3Confident49 Ų4970.2 Ų70.230%0.30139%0.389SS..EExtended strand (participates in β ladder)trans-86.6127.2173.3-49.60000108.9Q548 F550 K579Q548-T560 HydrophobicContact CB-CG2 4.02Å; Q548-T560 HydrophobicContact CG-CG2 3.89Å; F550-T560 HydrophobicContact CD1-CG2 4.04Å; F550-T560 WeakPolarHBondContact CD1-OG1 3.4Å; F550-T560 HydrophobicContact CE1-CG2 3.63Å; F550-T560 WeakPolarHBondContact CE1-OG1 3.34Å; F550-T560 HydrophobicContact CZ-CG2 4.24Å; T560-K579 PolarHBondContact O-NZ 2.9Å
561L80.8Confident78.4Confident2 Ų267.9 Ų67.91%0.0138%0.382CS..EExtended strand (participates in β ladder)trans-119133.6174.9-56.6168.1000108.7Q548 I549 V551 I559 V563 V572 K575 I576 K579Q548-L561 CarbonylContact C-O 3.57Å; Q548-L561 VanDerWaalsContact CA-O 3.23Å; Q548-L561 WeakPolarHBondContact CA-O 3.32Å; I549-L561 HydrophobicContact CD1-CD1 4.16Å; I549-L561 HydrophobicContact CG1-CB 3.86Å; I549-L561 HydrophobicContact CG1-CD1 4.25Å; I549-L561 PolarHBondContact N-O 2.82Å; I549-L561 PolarHBondContact O-N 3.14Å; V551-L561 HydrophobicContact CB-CD1 4.49Å; V551-L561 HydrophobicContact CG2-CD1 3.52Å; V551-L561 HydrophobicContact CG2-CG 4.36Å; I559-L561 HydrophobicContact CG2-CD2 3.96Å; I559-L561 HydrophobicContact CG2-CG 4.32Å; L561-V563 HydrophobicContact CB-CG1 4.45Å; L561-V572 HydrophobicContact CD1-CG1 3.95Å; L561-K575 HydrophobicContact CD2-CB 4.15Å; L561-I576 HydrophobicContact CD1-CD1 4.03Å; L561-I576 HydrophobicContact CD1-CG1 3.46Å; L561-I576 VanDerWaalsContact CD1-CG1 3.46Å; L561-I576 HydrophobicContact CD2-CG1 4.22Å; L561-I576 HydrophobicContact CG-CG1 4.41Å; L561-K579 HydrophobicContact CD2-CD 4.04Å
562E76.3Confident78.5Confident61 Ų6167.2 Ų67.229%0.28538%0.378SS..EExtended strand (participates in β ladder)trans-82.9132.1166.3-59.6-146.1141.500109.2Q510 G546 M547 Q548 K575Q510-E562 PolarHBondContact NE2-OE2 2.91Å; G546-E562 PolarHBondContact N-OE1 2.88Å; M547-E562 CarbonylContact O-C 3.6Å; M547-E562 WeakPolarHBondContact O-CA 3.34Å; Q548-E562 HydrophobicContact CG-CG 3.82Å; Q548-E562 PolarHBondContact NE2-OE1 2.71Å; E562-K575 WeakPolarHBondContact O-CD 3.42Å; E562-K575 PolarHBondContact O-NZ 3.21Å
563V78.7Confident78.9Confident12 Ų1261.4 Ų61.47%0.07335%0.353CS..  trans-135.6158-176.1-66.60000110.8M547 I549 L561 D567 V572 K575M547-V563 WeakPolarHBondContact CB-O 3.34Å; M547-V563 HydrophobicContact CG-CG2 4.04Å; M547-V563 PolarHBondContact O-N 2.85Å; M547-V563 VanDerWaalsContact O-O 3.09Å; M547-V563 HydrophobicContact SD-CG2 4.48Å; I549-V563 HydrophobicContact CB-CG2 4.37Å; I549-V563 HydrophobicContact CD1-CG1 3.66Å; I549-V563 HydrophobicContact CD1-CG2 4.47Å; I549-V563 HydrophobicContact CG1-CG1 3.72Å; I549-V563 HydrophobicContact CG1-CG2 4.1Å; I549-V563 HydrophobicContact CG2-CG2 3.63Å; L561-V563 HydrophobicContact CB-CG1 4.45Å; V563-D567 VanDerWaalsContact CA-OD2 3.28Å; V563-D567 WeakPolarHBondContact CA-OD2 3.26Å; V563-V572 HydrophobicContact CG1-CG2 4.15Å; V563-K575 HydrophobicContact CG1-CD 4.48Å
564E71.7Confident79.2Confident53 Ų5362.3 Ų62.325%0.24836%0.358CS..  trans-107.8157.2170.2-70.6-172.5-15300111.2Q501 P508 S566 D567Q501-E564 PolarHBondContact NE2-OE1 2.81Å; Q501-E564 VanDerWaalsContact NE2-OE1 3.16Å; P508-E564 WeakPolarHBondContact CD-OE1 3.23Å; E564-S566 PolarHBondContact O-N 2.93Å; E564-D567 PolarHBondContact N-OD2 2.79Å; E564-D567 WeakPolarHBondContact O-CB 3.41Å; E564-D567 PolarHBondContact O-N 2.93Å
565P72.8Confident79.8Confident123 Ų12356.1 Ų56.180%0.79932%0.323SS*.THydrogen-bonded Turntrans-57.2-21.9176.4-24.734.3000114.3M547M547-P565 HydrophobicContact SD-CG 4.49Å
566S74.1Confident80.2Confident88 Ų8850.3 Ų50.362%0.61529%0.288SS*.THydrogen-bonded Turntrans-87.1-12.3178.453.50000114E564 T568E564-S566 PolarHBondContact O-N 2.93Å; S566-T568 PolarHBondContact O-N 3.49Å
567D76.4Confident80.7Confident24 Ų2451.2 Ų51.213%0.12828%0.278CS..  trans-62.5134.5-175.6-89.6-33.5000111.7V563 E564 N571 K575 A599V563-D567 VanDerWaalsContact CA-OD2 3.28Å; V563-D567 WeakPolarHBondContact CA-OD2 3.26Å; E564-D567 PolarHBondContact N-OD2 2.79Å; E564-D567 WeakPolarHBondContact O-CB 3.41Å; E564-D567 PolarHBondContact O-N 2.93Å; D567-N571 HydrophobicContact CB-CB 4.11Å; D567-N571 WeakPolarHBondContact OD1-CB 3.48Å; D567-N571 PolarHBondContact OD1-ND2 2.78Å; D567-K575 IonicContact OD1-NZ 2.82Å; D567-K575 IonicContact OD2-NZ 3.41Å; D567-K575 PolarHBondContact OD2-NZ 3.09Å; D567-A599 WeakPolarHBondContact O-CB 3.49Å
568T82.6Confident80.8Confident68 Ų6852.2 Ų52.242%0.41729%0.288SS..  trans-86.7170.4173.181.70000112S566 E570 N571 V572S566-T568 PolarHBondContact O-N 3.49Å; T568-E570 PolarHBondContact O-N 3.36Å; T568-E570 PolarHBondContact OG1-N 3.05Å; T568-N571 WeakPolarHBondContact O-CB 3.39Å; T568-N571 PolarHBondContact O-N 3.33Å; T568-N571 VanDerWaalsContact O-N 3.14Å; T568-N571 PolarHBondContact OG1-N 2.91Å; T568-N571 PolarHBondContact OG1-OD1 2.7Å; T568-V572 WeakPolarHBondContact O-CG2 3.32Å; T568-V572 PolarHBondContact O-N 3.17Å
569I81.3Confident80.9Confident20 Ų2054.9 Ų54.910%0.10329%0.294CS..Hα-helixtrans-62.6-34.3177.2-69.6-64.5000110.3N571 V572 K573 L589 T598 A599I569-N571 VanDerWaalsContact C-N 3.35Å; I569-V572 PolarHBondContact O-N 2.78Å; I569-K573 HydrophobicContact CG2-CD 4.47Å; I569-K573 HydrophobicContact CG2-CG 4.46Å; I569-K573 WeakPolarHBondContact O-CG 3.47Å; I569-K573 PolarHBondContact O-N 3.1Å; I569-L589 HydrophobicContact CG2-CD1 4.25Å; I569-T598 VanDerWaalsContact CG1-C 3.45Å; I569-A599 HydrophobicContact CD1-CB 3.98Å; I569-A599 HydrophobicContact CG1-CB 3.97Å
570E82.6Confident81.1Confident99 Ų9957.6 Ų57.646%0.46331%0.307SS..Hα-helixtrans-69.5-36.4178.2-149.762.8-16400111T568 V572 K573 T574T568-E570 PolarHBondContact O-N 3.36Å; T568-E570 PolarHBondContact OG1-N 3.05Å; E570-V572 PolarHBondContact O-N 3.29Å; E570-K573 PolarHBondContact O-N 3.11Å; E570-K573 IonicContact OE2-NZ 3.94Å; E570-T574 PolarHBondContact O-N 3.12Å; E570-T574 PolarHBondContact O-OG1 2.89Å
571N83.1Confident81Confident65 Ų6558.1 Ų58.135%0.34832%0.322SS..Hα-helixtrans-59.2-48.2170.9-58.931.5000110.3D567 T568 I569 K573 T574 K575D567-N571 HydrophobicContact CB-CB 4.11Å; D567-N571 WeakPolarHBondContact OD1-CB 3.48Å; D567-N571 PolarHBondContact OD1-ND2 2.78Å; T568-N571 WeakPolarHBondContact O-CB 3.39Å; T568-N571 PolarHBondContact O-N 3.33Å; T568-N571 VanDerWaalsContact O-N 3.14Å; T568-N571 PolarHBondContact OG1-N 2.91Å; T568-N571 PolarHBondContact OG1-OD1 2.7Å; I569-N571 VanDerWaalsContact C-N 3.35Å; N571-K573 VanDerWaalsContact C-N 3.33Å; N571-K573 PolarHBondContact O-N 2.84Å; N571-T574 PolarHBondContact O-N 2.9Å; N571-K575 WeakPolarHBondContact O-CG 3.2Å; N571-K575 PolarHBondContact O-N 3.37Å
572V84.2Confident80.8Confident6 Ų661.1 Ų61.14%0.03634%0.337CS..Hα-helixtrans-61-42.6179174.70000111.3I549 L561 V563 T568 I569 E570 K575 I576 L589I549-V572 HydrophobicContact CD1-CG1 3.72Å; I549-V572 HydrophobicContact CD1-CG2 4.06Å; L561-V572 HydrophobicContact CD1-CG1 3.95Å; V563-V572 HydrophobicContact CG1-CG2 4.15Å; T568-V572 WeakPolarHBondContact O-CG2 3.32Å; T568-V572 PolarHBondContact O-N 3.17Å; I569-V572 PolarHBondContact O-N 2.78Å; E570-V572 PolarHBondContact O-N 3.29Å; V572-K575 PolarHBondContact O-N 3.06Å; V572-I576 HydrophobicContact CG1-CD1 4.2Å; V572-I576 WeakPolarHBondContact O-CG1 3.44Å; V572-I576 PolarHBondContact O-N 3.44Å; V572-L589 HydrophobicContact CB-CD1 4.42Å; V572-L589 HydrophobicContact CG1-CD1 3.87Å
573K86Confident80.8Confident36 Ų3660 Ų6016%0.15734%0.336CS..Hα-helixtrans-63.3-41.9176.8-74.6178.8168.2-165.20112.7I569 E570 N571 K575 I576 Q577 P584 Q587 L589I569-K573 HydrophobicContact CG2-CD 4.47Å; I569-K573 HydrophobicContact CG2-CG 4.46Å; I569-K573 WeakPolarHBondContact O-CG 3.47Å; I569-K573 PolarHBondContact O-N 3.1Å; E570-K573 PolarHBondContact O-N 3.11Å; E570-K573 IonicContact OE2-NZ 3.94Å; N571-K573 VanDerWaalsContact C-N 3.33Å; N571-K573 PolarHBondContact O-N 2.84Å; K573-K575 VanDerWaalsContact C-N 3.31Å; K573-K575 PolarHBondContact O-N 3.49Å; K573-I576 WeakPolarHBondContact O-CB 3.03Å; K573-I576 PolarHBondContact O-N 2.72Å; K573-I576 VanDerWaalsContact O-N 3.14Å; K573-Q577 PolarHBondContact O-N 2.98Å; K573-P584 HydrophobicContact CB-CB 4Å; K573-P584 HydrophobicContact CB-CG 4.47Å; K573-P584 HydrophobicContact CD-CB 4.11Å; K573-P584 PolarHBondContact NZ-O 2.76Å; K573-Q587 HydrophobicContact CG-CB 4.31Å; K573-Q587 PolarHBondContact O-NE2 3.24Å; K573-Q587 PolarHBondContact O-OE1 3.49Å; K573-L589 HydrophobicContact CG-CD1 3.78Å; K573-L589 HydrophobicContact CG-CG 4.46Å
574T85.1Confident80.7Confident57 Ų5760.5 Ų60.535%0.3534%0.339SS..Hα-helixtrans-60.5-44.8176.1-50.40000109.9E570 N571 I576 Q577 D578E570-T574 PolarHBondContact O-N 3.12Å; E570-T574 PolarHBondContact O-OG1 2.89Å; N571-T574 PolarHBondContact O-N 2.9Å; T574-I576 VanDerWaalsContact C-N 3.27Å; T574-I576 PolarHBondContact O-N 3.35Å; T574-Q577 WeakPolarHBondContact O-CA 3.48Å; T574-Q577 VanDerWaalsContact O-CB 3.31Å; T574-Q577 WeakPolarHBondContact O-CB 3.3Å; T574-Q577 PolarHBondContact O-N 2.86Å; T574-D578 PolarHBondContact O-N 3.07Å
575K86.7Confident81.1Confident60 Ų6064.4 Ų64.426%0.26136%0.361SS..Hα-helixtrans-60.2-32.8174.8-69.5177.9173.6-170.20113.7L561 E562 V563 D567 N571 V572 K573 K579L561-K575 HydrophobicContact CD2-CB 4.15Å; E562-K575 WeakPolarHBondContact O-CD 3.42Å; E562-K575 PolarHBondContact O-NZ 3.21Å; V563-K575 HydrophobicContact CG1-CD 4.48Å; D567-K575 IonicContact OD1-NZ 2.82Å; D567-K575 IonicContact OD2-NZ 3.41Å; D567-K575 PolarHBondContact OD2-NZ 3.09Å; N571-K575 WeakPolarHBondContact O-CG 3.2Å; N571-K575 PolarHBondContact O-N 3.37Å; V572-K575 PolarHBondContact O-N 3.06Å; K573-K575 VanDerWaalsContact C-N 3.31Å; K573-K575 PolarHBondContact O-N 3.49Å; K575-K579 PolarHBondContact O-N 2.91Å
576I83.8Confident81.3Confident7 Ų765 Ų654%0.03635%0.353CS..Hα-helixtrans-71.5-41.1173.1-66.2163.6000111V551 L561 V572 K573 T574 D578 K579 E580 Q587 L589V551-I576 HydrophobicContact CG1-CD1 4.14Å; V551-I576 HydrophobicContact CG2-CD1 4.15Å; L561-I576 HydrophobicContact CD1-CD1 4.03Å; L561-I576 HydrophobicContact CD1-CG1 3.46Å; L561-I576 VanDerWaalsContact CD1-CG1 3.46Å; L561-I576 HydrophobicContact CD2-CG1 4.22Å; L561-I576 HydrophobicContact CG-CG1 4.41Å; V572-I576 HydrophobicContact CG1-CD1 4.2Å; V572-I576 WeakPolarHBondContact O-CG1 3.44Å; V572-I576 PolarHBondContact O-N 3.44Å; K573-I576 WeakPolarHBondContact O-CB 3.03Å; K573-I576 PolarHBondContact O-N 2.72Å; K573-I576 VanDerWaalsContact O-N 3.14Å; T574-I576 VanDerWaalsContact C-N 3.27Å; T574-I576 PolarHBondContact O-N 3.35Å; I576-D578 VanDerWaalsContact C-N 3.28Å; I576-D578 PolarHBondContact O-N 3.17Å; I576-K579 PolarHBondContact O-N 3.24Å; I576-E580 PolarHBondContact O-N 3.13Å; I576-Q587 HydrophobicContact CG2-CG 4.49Å; I576-L589 HydrophobicContact CD1-CD1 4.21Å; I576-L589 HydrophobicContact CD1-CD2 3.6Å; I576-L589 HydrophobicContact CD1-CG 4.39Å
577Q85.1Confident81.6Confident69 Ų6961.6 Ų61.632%0.32233%0.328SS..Hα-helixtrans-58.3-44.8175.8-178.2-178.715.300110.3K573 T574 K579 G581 I582K573-Q577 PolarHBondContact O-N 2.98Å; T574-Q577 WeakPolarHBondContact O-CA 3.48Å; T574-Q577 VanDerWaalsContact O-CB 3.31Å; T574-Q577 WeakPolarHBondContact O-CB 3.3Å; T574-Q577 PolarHBondContact O-N 2.86Å; Q577-K579 VanDerWaalsContact C-N 3.31Å; Q577-K579 PolarHBondContact O-N 2.94Å; Q577-G581 WeakPolarHBondContact O-CA 3.46Å; Q577-G581 PolarHBondContact O-N 3.49Å; Q577-I582 VanDerWaalsContact CA-O 3.27Å; Q577-I582 WeakPolarHBondContact CA-O 3.38Å; Q577-I582 WeakPolarHBondContact CB-O 3.13Å; Q577-I582 WeakPolarHBondContact CG-O 3.28Å
578D81.6Confident81.7Confident124 Ų12468.8 Ų68.866%0.66335%0.353SS*.Hα-helixtrans-64-35.5-179.6-64.4-26.6000112.6T574 I576T574-D578 PolarHBondContact O-N 3.07Å; I576-D578 VanDerWaalsContact C-N 3.28Å; I576-D578 PolarHBondContact O-N 3.17Å
579K82.5Confident81.5Confident121 Ų12166.6 Ų66.653%0.52634%0.339SS..Hα-helixtrans-82.4-35.5179.6-82.6-161.1177.9-173.70114.8I559 T560 L561 K575 I576 Q577I559-K579 HydrophobicContact CG2-CB 4.47Å; I559-K579 HydrophobicContact CG2-CD 4.05Å; T560-K579 PolarHBondContact O-NZ 2.9Å; L561-K579 HydrophobicContact CD2-CD 4.04Å; K575-K579 PolarHBondContact O-N 2.91Å; I576-K579 PolarHBondContact O-N 3.24Å; Q577-K579 VanDerWaalsContact C-N 3.31Å; Q577-K579 PolarHBondContact O-N 2.94Å
580E84.5Confident81.1Confident66 Ų6670.9 Ų70.931%0.30836%0.361SS..Hα-helixtrans-121-5.6-168.7-62.5-69.1138.600113.6K557 I559 I576 I582K557-E580 WeakPolarHBondContact CE-OE1 3.29Å; K557-E580 IonicContact NZ-OE1 2.72Å; K557-E580 PolarHBondContact NZ-OE1 2.83Å; K557-E580 IonicContact NZ-OE2 2.66Å; K557-E580 PolarHBondContact NZ-OE2 2.8Å; I559-E580 HydrophobicContact CD1-CG 3.52Å; I559-E580 HydrophobicContact CG1-CG 4Å; I576-E580 PolarHBondContact O-N 3.13Å; E580-I582 VanDerWaalsContact C-N 3.29Å; E580-I582 HydrophobicContact CB-CD1 4.23Å; E580-I582 HydrophobicContact CB-CG1 4.19Å; E580-I582 PolarHBondContact O-N 2.83Å
581G80.4Confident80.5Confident59 Ų5968.2 Ų68.261%0.60835%0.348SS*.  trans73.713.2-179.900000114.8Q577 P583Q577-G581 WeakPolarHBondContact O-CA 3.46Å; Q577-G581 PolarHBondContact O-N 3.49Å; G581-P583 WeakPolarHBondContact O-CD 3.28Å
582I78.3Confident79.7Confident65 Ų6569.4 Ų69.433%0.33337%0.366SS..  trans-92.4118.8-177.3-54.5174.2000109.8Q577 E580 Q586 Q587Q577-I582 VanDerWaalsContact CA-O 3.27Å; Q577-I582 WeakPolarHBondContact CA-O 3.38Å; Q577-I582 WeakPolarHBondContact CB-O 3.13Å; Q577-I582 WeakPolarHBondContact CG-O 3.28Å; E580-I582 VanDerWaalsContact C-N 3.29Å; E580-I582 HydrophobicContact CB-CD1 4.23Å; E580-I582 HydrophobicContact CB-CG1 4.19Å; E580-I582 PolarHBondContact O-N 2.83Å; I582-Q586 HydrophobicContact CG2-CB 4.04Å; I582-Q587 HydrophobicContact CB-CG 4.34Å; I582-Q587 HydrophobicContact CG2-CG 3.8Å; I582-Q587 PolarHBondContact O-NE2 2.88Å
583P75.4Confident78.4Confident39 Ų3972.6 Ų72.625%0.25340%0.401SS..  trans-59.8144.4178.5-27.537.5000114.4G581 D585 Q586 Q587G581-P583 WeakPolarHBondContact O-CD 3.28Å; P583-D585 VanDerWaalsContact C-N 3.27Å; P583-D585 WeakPolarHBondContact CB-OD1 3.4Å; P583-D585 PolarHBondContact O-N 2.82Å; P583-D585 VanDerWaalsContact O-N 3.16Å; P583-Q586 HydrophobicContact CB-CG 4.37Å; P583-Q586 WeakPolarHBondContact O-CA 3.33Å; P583-Q586 WeakPolarHBondContact O-CB 3.35Å; P583-Q586 PolarHBondContact O-N 3.13Å; P583-Q587 WeakPolarHBondContact O-CG 3.48Å; P583-Q587 PolarHBondContact O-N 3.25Å
584P76Confident76.8Confident21 Ų2178.4 Ų78.414%0.13643%0.426CS..THydrogen-bonded Turntrans-57.5-29.4-175.1-29.936.5000116K573 Q586 Q587K573-P584 HydrophobicContact CB-CB 4Å; K573-P584 HydrophobicContact CB-CG 4.47Å; K573-P584 HydrophobicContact CD-CB 4.11Å; K573-P584 PolarHBondContact NZ-O 2.76Å; P584-Q586 VanDerWaalsContact C-N 3.33Å; P584-Q587 PolarHBondContact O-N 3.29Å
585D80Confident75.3Confident135 Ų13584 Ų8472%0.72244%0.44SS*.THydrogen-bonded Turntrans-72.1-26.8175.862.7-42.8000112.5P583 Q587P583-D585 VanDerWaalsContact C-N 3.27Å; P583-D585 WeakPolarHBondContact CB-OD1 3.4Å; P583-D585 PolarHBondContact O-N 2.82Å; P583-D585 VanDerWaalsContact O-N 3.16Å; D585-Q587 VanDerWaalsContact C-N 3.34Å
586Q77.6Confident73.7Confident136 Ų13683.5 Ų83.564%0.63644%0.439SS*.THydrogen-bonded Turntrans-86.3-7173.7-59.1-174.60.300112.9I582 P583 P584I582-Q586 HydrophobicContact CG2-CB 4.04Å; P583-Q586 HydrophobicContact CB-CG 4.37Å; P583-Q586 WeakPolarHBondContact O-CA 3.33Å; P583-Q586 WeakPolarHBondContact O-CB 3.35Å; P583-Q586 PolarHBondContact O-N 3.13Å; P584-Q586 VanDerWaalsContact C-N 3.33Å
587Q80.8Confident72.2Confident17 Ų1791.9 Ų91.98%0.07948%0.478CS..  trans-92.1130179.6-63.7178.530.700112.5K573 I576 I582 P583 P584 D585K573-Q587 HydrophobicContact CG-CB 4.31Å; K573-Q587 PolarHBondContact O-NE2 3.24Å; K573-Q587 PolarHBondContact O-OE1 3.49Å; I576-Q587 HydrophobicContact CG2-CG 4.49Å; I582-Q587 HydrophobicContact CB-CG 4.34Å; I582-Q587 HydrophobicContact CG2-CG 3.8Å; I582-Q587 PolarHBondContact O-NE2 2.88Å; P583-Q587 WeakPolarHBondContact O-CG 3.48Å; P583-Q587 PolarHBondContact O-N 3.25Å; P584-Q587 PolarHBondContact O-N 3.29Å; D585-Q587 VanDerWaalsContact C-N 3.34Å
588R78.1Confident70.2Confident175 Ų17592.8 Ų92.866%0.6649%0.489SS*.  trans-117.5105.8166.8-103.7-177.5176.7-175.5-0.4110.3
589L79Confident68.2Low21 Ų2188 Ų8811%0.1147%0.466CS..  trans-86.5128.3172.9-63.8174.1000110.3V551 I569 V572 K573 I576V551-L589 HydrophobicContact CG1-CD2 4.12Å; I569-L589 HydrophobicContact CG2-CD1 4.25Å; V572-L589 HydrophobicContact CB-CD1 4.42Å; V572-L589 HydrophobicContact CG1-CD1 3.87Å; K573-L589 HydrophobicContact CG-CD1 3.78Å; K573-L589 HydrophobicContact CG-CG 4.46Å; I576-L589 HydrophobicContact CD1-CD1 4.21Å; I576-L589 HydrophobicContact CD1-CD2 3.6Å; I576-L589 HydrophobicContact CD1-CG 4.39Å
590I71.6Confident66Low110 Ų11087.1 Ų87.156%0.56448%0.481SS*.EExtended strand (participates in β ladder)trans-126.4129.4-179.8-56175.5000107.6
591F71.8Confident63.7Low44 Ų4486.1 Ų86.119%0.19348%0.482CS..EExtended strand (participates in β ladder)trans-125.1128.4175.2-178.1-112.7000109.3G593 K594 Q596 S601 M602 A603 I604F591-G593 PolarHBondContact O-N 3.49Å; F591-G593 VanDerWaalsContact O-N 3.16Å; F591-K594 PolarHBondContact N-O 2.97Å; F591-K594 PolarHBondContact O-N 3.33Å; F591-K594 VanDerWaalsContact O-N 3.1Å; F591-K594 VanDerWaalsContact O-O 3.13Å; F591-Q596 HydrophobicContact CB-CG 3.85Å; F591-S601 WeakPolarHBondContact CD1-O 3.31Å; F591-S601 WeakPolarHBondContact CE1-O 3.48Å; F591-M602 HydrophobicContact CB-CE 4.21Å; F591-M602 HydrophobicContact CB-CG 4.21Å; F591-M602 HydrophobicContact CD2-CG 4.19Å; F591-M602 HydrophobicContact CG-CG 4.02Å; F591-A603 WeakPolarHBondContact CZ-O 3.42Å; F591-I604 HydrophobicContact CD2-CD1 4.17Å; F591-I604 HydrophobicContact CD2-CG1 4.22Å; F591-I604 HydrophobicContact CE2-CD1 3.71Å; F591-I604 HydrophobicContact CE2-CG1 3.33Å; F591-I604 HydrophobicContact CZ-CG1 4Å
592A65.2Low61.7Low89 Ų8985.1 Ų85.174%0.73646%0.462SS*.THydrogen-bonded Turntrans49.739-179.500000114.8K594A592-K594 VanDerWaalsContact C-N 3.27Å; A592-K594 PolarHBondContact O-N 3.27Å
593G56.9Low59.3Low74 Ų7485.8 Ų85.876%0.76348%0.477SS*.THydrogen-bonded Turntrans75.14.3177.500000115.7F591F591-G593 PolarHBondContact O-N 3.49Å; F591-G593 VanDerWaalsContact O-N 3.16Å
594K51.8Low57.2Low158 Ų15888.8 Ų88.869%0.68749%0.49SS*.EExtended strand (participates in β ladder)trans-118142.3173.2-71.3-174.9179.6179.30111.7F591 A592 Q596F591-K594 PolarHBondContact N-O 2.97Å; F591-K594 PolarHBondContact O-N 3.33Å; F591-K594 VanDerWaalsContact O-N 3.1Å; F591-K594 VanDerWaalsContact O-O 3.13Å; A592-K594 VanDerWaalsContact C-N 3.27Å; A592-K594 PolarHBondContact O-N 3.27Å; K594-Q596 PolarHBondContact O-N 3.13Å
595R55Low54.8Low173 Ų17393.1 Ų93.165%0.65352%0.516SS*.EExtended strand (participates in β ladder)trans-71119.6174.4-161177.6-176.2-166.3-2.4108
596Q53.4Low52.3Low50 Ų5097.4 Ų97.423%0.23452%0.523CS..  trans-89.1140.6-175.6-72.3-68.5-18.300111.6F591 K594 S601F591-Q596 HydrophobicContact CB-CG 3.85Å; K594-Q596 PolarHBondContact O-N 3.13Å; Q596-S601 PolarHBondContact OE1-OG 3.46Å; Q596-S601 VanDerWaalsContact OE1-OG 3.05Å
597Q51.2Low50Low184 Ų184101.2 Ų101.286%0.8653%0.533SS*.SBendtrans-107.3-11.5174-71.6-176.6-11.300112.8
598T42.1Very low47.7Very low88 Ų88115.2 Ų115.254%0.5459%0.585SS.*  trans-143148.7-178.846.10000111.1I569I569-T598 VanDerWaalsContact CG1-C 3.45Å
599A40.3Very low46.2Very low22 Ų22112.2 Ų112.218%0.18258%0.582CS.*G310 helixtrans-80.7-26.3-170.400000114.4D567 I569 S601 M602D567-A599 WeakPolarHBondContact O-CB 3.49Å; I569-A599 HydrophobicContact CD1-CB 3.98Å; I569-A599 HydrophobicContact CG1-CB 3.97Å; A599-S601 PolarHBondContact O-N 2.81Å; A599-M602 PolarHBondContact O-N 2.91Å; A599-M602 VanDerWaalsContact O-N 3.11Å
600A37.6Very low44.5Very low103 Ų103117 Ų11785%0.85161%0.606SS**G310 helixtrans-58.2-15.2-179.100000113.9
601S36Very low43Very low45 Ų45117.4 Ų117.432%0.31561%0.609SS.*G310 helixtrans-85.7-5.4-179.6-38.50000114.7F591 Q596 A599 A603F591-S601 WeakPolarHBondContact CD1-O 3.31Å; F591-S601 WeakPolarHBondContact CE1-O 3.48Å; Q596-S601 PolarHBondContact OE1-OG 3.46Å; Q596-S601 VanDerWaalsContact OE1-OG 3.05Å; A599-S601 PolarHBondContact O-N 2.81Å; S601-A603 PolarHBondContact O-N 3.05Å
602M36.6Very low41.3Very low38 Ų38121.7 Ų121.719%0.18763%0.633CS.*  trans-86.673.4176.7-89.8-174.7156.900111.1I549 F591 A599I549-M602 HydrophobicContact CD1-SD 4.37Å; F591-M602 HydrophobicContact CB-CE 4.21Å; F591-M602 HydrophobicContact CB-CG 4.21Å; F591-M602 HydrophobicContact CD2-CG 4.19Å; F591-M602 HydrophobicContact CG-CG 4.02Å; A599-M602 PolarHBondContact O-N 2.91Å; A599-M602 VanDerWaalsContact O-N 3.11Å
603A28.2Very low39.8Very low79 Ų79123.8 Ų123.865%0.65363%0.627SS**  trans-93.7100.3162.300000109.1F591 S601F591-A603 WeakPolarHBondContact CZ-O 3.42Å; S601-A603 PolarHBondContact O-N 3.05Å
604I32.1Very low38.6Very low102 Ų102127.1 Ų127.152%0.52362%0.618SS.*  trans-105.7105.1163.6-64.5176.4000107.8F591F591-I604 HydrophobicContact CD2-CD1 4.17Å; F591-I604 HydrophobicContact CD2-CG1 4.22Å; F591-I604 HydrophobicContact CE2-CD1 3.71Å; F591-I604 HydrophobicContact CE2-CG1 3.33Å; F591-I604 HydrophobicContact CZ-CG1 4Å
605V25.7Very low37.7Very low113 Ų113124.9 Ų124.969%0.68561%0.613SS**  trans-83.4120.4155.8173.80000107.3Y607V605-Y607 HydrophobicContact CG1-CD2 4.32Å
606Y27.3Very low36.3Very low224 Ų224121.2 Ų121.288%0.87861%0.61SS**  trans-148.7125.5138.1-95.9-77.4000108.7
607Y28.5Very low34.9Very low216 Ų216127.1 Ų127.185%0.84764%0.641SS**  trans-68.6139.8-177.8-92.2-98.9000113.3V605V605-Y607 HydrophobicContact CG1-CD2 4.32Å
608R33.5Very low33.4Very low311 Ų311121.9 Ų121.9100%1.17462%0.621SS**  -143.80112.4-129.8-174.9-165-169.64.4110.9

Retrieved 608 of 608 residues in 399.2 ms (Link to these results)