A0A077ZE72_TRITR Loading...

Amino acid permease

AlphaFold DB , UniProt , Accession A0A077ZE72, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 558 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.6	Very low	28.5	Very low	237 Å²	237	185.4 Å²	185.4	100%	1.167	87%	0.869	S	S	*	*				0	92.3	0	-73.2	175	176.6	0	0	109
2	S	29.8	Very low	28.3	Very low	121 Å²	121	189.7 Å²	189.7	85%	0.846	87%	0.871	S	S	*	*			trans	-85.6	114.4	-179.2	57.7	0	0	0	0	110.5
3	F	28.8	Very low	28.1	Very low	186 Å²	186	187.8 Å²	187.8	82%	0.816	87%	0.872	S	S	*	*			trans	-60.8	132.3	-177.5	-94.5	-99.6	0	0	0	113.2	W5	F3-W5 PolarHBondContact O-N 3.14Å; F3-W5 VanDerWaalsContact O-N 3.14Å
4	P	30.6	Very low	27.9	Very low	109 Å²	109	183.9 Å²	183.9	71%	0.708	87%	0.868	S	S	*	*			trans	-89.8	71.4	-173.9	35.6	-34.2	0	0	0	112.4
5	W	25.6	Very low	27.6	Very low	231 Å²	231	178.5 Å²	178.5	88%	0.875	86%	0.858	S	S	*	*			trans	-94.9	-8.1	168	-91.5	67.9	0	0	0	114	F3	F3-W5 PolarHBondContact O-N 3.14Å; F3-W5 VanDerWaalsContact O-N 3.14Å
6	K	28.1	Very low	27.4	Very low	202 Å²	202	184 Å²	184	88%	0.878	87%	0.868	S	S	*	*	S	Bend	trans	-87.8	-5.9	-176.9	-77.5	-170.1	176.6	-176.7	0	116.4
7	R	28.6	Very low	27.3	Very low	224 Å²	224	183.8 Å²	183.8	85%	0.845	86%	0.863	S	S	*	*	S	Bend	trans	-91.5	-13.2	-175.7	-78.6	-174.1	179.2	-179.8	0.4	115.5
8	A	28.7	Very low	27.3	Very low	96 Å²	96	181.3 Å²	181.3	79%	0.793	86%	0.856	S	S	*	*	S	Bend	trans	-81.2	-20.8	-175.9	0	0	0	0	0	114.7
9	F	27.4	Very low	27.4	Very low	209 Å²	209	182.1 Å²	182.1	92%	0.917	86%	0.859	S	S	*	*	S	Bend	trans	-89.7	-8.9	-175	-118.8	-88.9	0	0	0	115.2
10	K	27.6	Very low	27.2	Very low	189 Å²	189	183 Å²	183	82%	0.822	86%	0.86	S	S	*	*	S	Bend	trans	-102.5	9.8	-166.7	-136	179.3	-175.3	-177.4	0	116
11	R	25.6	Very low	27.3	Very low	235 Å²	235	180.4 Å²	180.4	89%	0.887	86%	0.859	S	S	*	*	S	Bend	trans	-114.1	14.8	-172.3	-97	-169.5	-178.3	-169.7	0.9	117.3
12	R	26.2	Very low	26.9	Very low	237 Å²	237	174.4 Å²	174.4	89%	0.894	84%	0.84	S	S	*	*	S	Bend	trans	-122.2	-3.2	-177.7	-109.6	-177.7	-167.9	178.1	3.5	120
13	N	26.2	Very low	26.9	Very low	165 Å²	165	174.2 Å²	174.2	88%	0.882	84%	0.839	S	S	*	*			trans	-133.9	51.4	-179.1	-91.9	5.2	0	0	0	114.2
14	T	24.8	Very low	26.6	Very low	134 Å²	134	170.5 Å²	170.5	82%	0.822	84%	0.836	S	S	*	*			trans	-125.1	82.5	167.2	52.4	0	0	0	0	109.9
15	S	24.1	Very low	26.6	Very low	103 Å²	103	173.3 Å²	173.3	72%	0.72	84%	0.843	S	S	*	*			trans	-171.4	66.4	157.5	-178.4	0	0	0	0	109.8
16	W	24	Very low	26.7	Very low	266 Å²	266	167.7 Å²	167.7	100%	1.008	84%	0.836	S	S	*	*			trans	-126.1	90.2	153.1	-80	92.8	0	0	0	105.1
17	K	26.2	Very low	26.4	Very low	180 Å²	180	166.4 Å²	166.4	78%	0.783	84%	0.838	S	S	*	*			trans	-89.5	123.1	170.2	-85.8	-172.1	172.1	-174.4	0	107.6
18	D	27.5	Very low	26.3	Very low	140 Å²	140	167.5 Å²	167.5	75%	0.749	84%	0.842	S	S	*	*			trans	51.9	83.7	130.6	-50	-39.7	0	0	0	118.1
19	E	28.7	Very low	26.1	Very low	195 Å²	195	172 Å²	172	91%	0.911	85%	0.847	S	S	*	*			trans	-124.5	103.8	141.2	-83.9	-174.8	168.1	0	0	108.9
20	K	23.4	Very low	26.1	Very low	201 Å²	201	166.5 Å²	166.5	87%	0.874	84%	0.84	S	S	*	*			trans	-86.5	126.6	165.2	-82.5	179.6	175.3	177.5	0	108.5
21	P	29.4	Very low	25.9	Very low	128 Å²	128	164.1 Å²	164.1	83%	0.831	84%	0.841	S	S	*	*			trans	-96	112.6	146.7	4.7	15.1	0	0	0	107.9
22	S	23.9	Very low	26.1	Very low	111 Å²	111	158.3 Å²	158.3	78%	0.776	83%	0.834	S	S	*	*			trans	-75.4	120.8	162.2	50.4	0	0	0	0	109.6
23	S	30	Very low	25.9	Very low	118 Å²	118	152.2 Å²	152.2	83%	0.825	83%	0.827	S	S	*	*			trans	-177.6	124.6	133.7	49.7	0	0	0	0	111.3
24	S	23	Very low	26.1	Very low	107 Å²	107	150.9 Å²	150.9	75%	0.748	83%	0.825	S	S	*	*			trans	-64	148.3	165.7	47	0	0	0	0	112.6
25	I	29.2	Very low	26	Very low	169 Å²	169	149 Å²	149	87%	0.867	82%	0.817	S	S	*	*			trans	-169.9	145	132.9	-90.5	147.9	0	0	0	108.1
26	P	27.6	Very low	25.9	Very low	113 Å²	113	148.5 Å²	148.5	73%	0.734	81%	0.814	S	S	*	*			trans	-105.1	168	-147.6	36.9	-26.9	0	0	0	115.7
27	L	22.4	Very low	26	Very low	175 Å²	175	143.9 Å²	143.9	92%	0.916	80%	0.804	S	S	*	*			trans	-25.4	127.5	167.2	-71.9	131.9	0	0	0	115.8
28	R	26.7	Very low	25.9	Very low	247 Å²	247	143 Å²	143	93%	0.932	80%	0.803	S	S	*	*			trans	-129	130.2	149.3	-113.6	-176.1	-178.4	-154.4	0.1	110.1
29	E	23.8	Very low	25.6	Very low	189 Å²	189	141.3 Å²	141.3	88%	0.883	80%	0.801	S	S	*	*			trans	-63.2	155.2	177.8	-61.6	159.6	143.8	0	0	112.4
30	A	29	Very low	25.6	Very low	94 Å²	94	141.4 Å²	141.4	78%	0.777	80%	0.802	S	S	*	*				145.3	108.9	127	0	0	0	0	0	110.5	P32	A30-P32 WeakPolarHBondContact O-CD 3.38Å
31	V	22.9	Very low	25.6	Very low	139 Å²	139	136.2 Å²	136.2	84%	0.842	80%	0.796	S	S	*	*			trans	-81	131.1	166.3	174	0	0	0	0	108.1
32	P	29.9	Very low	25.4	Very low	113 Å²	113	136.9 Å²	136.9	73%	0.734	80%	0.798	S	S	*	*			trans	-119.2	121	147.8	30	-16.7	0	0	0	109.9	A30	A30-P32 WeakPolarHBondContact O-CD 3.38Å
33	S	22.2	Very low	25.3	Very low	109 Å²	109	135.8 Å²	135.8	76%	0.762	80%	0.795	S	S	*	*			trans	-70.9	122.1	161.6	49.8	0	0	0	0	109.6
34	V	30	Very low	25.2	Very low	137 Å²	137	142 Å²	142	83%	0.83	80%	0.8	S	S	*	*			trans	-135.9	132.5	155.5	-178.9	0	0	0	0	108.9
35	S	22.9	Very low	25	Very low	95 Å²	95	142 Å²	142	66%	0.664	80%	0.801	S	S	*	*			trans	-72.2	158.1	-174.2	48.4	0	0	0	0	114.3
36	S	22.1	Very low	24.9	Very low	93 Å²	93	141.5 Å²	141.5	65%	0.65	80%	0.8	S	S	*	*			trans	34.9	126	139.1	63.1	0	0	0	0	120
37	E	25.6	Very low	24.7	Very low	168 Å²	168	143.5 Å²	143.5	79%	0.785	81%	0.805	S	S	*	*			trans	145.6	107.8	139.8	-82	167	-178.8	0	0	106.9
38	E	24.4	Very low	24.8	Very low	163 Å²	163	143.7 Å²	143.7	76%	0.762	80%	0.801	S	S	*	*				119.4	121.2	80.7	-96.9	-174.2	150.9	0	0	107.1
39	S	21.4	Very low	24.6	Very low	103 Å²	103	140.5 Å²	140.5	72%	0.72	80%	0.796	S	S	*	*			trans	46.9	101.8	131.1	-49.9	0	0	0	0	118.2
40	Q	28.5	Very low	24.7	Very low	197 Å²	197	137.4 Å²	137.4	92%	0.921	79%	0.79	S	S	*	*				-164.4	110.5	128	-106.7	166.6	25	0	0	111.1
41	A	21.6	Very low	24.4	Very low	92 Å²	92	139.6 Å²	139.6	76%	0.76	79%	0.788	S	S	*	*			trans	-62.1	142.5	155.5	0	0	0	0	0	109.1
42	V	26.2	Very low	24.5	Very low	143 Å²	143	137.6 Å²	137.6	87%	0.867	79%	0.786	S	S	*	*			trans	179.3	134.1	133.3	152.4	0	0	0	0	109.5
43	A	22.8	Very low	24.2	Very low	87 Å²	87	137.1 Å²	137.1	72%	0.719	78%	0.781	S	S	*	*			trans	-28	137.6	176.5	0	0	0	0	0	118
44	R	26.2	Very low	24.2	Very low	248 Å²	248	142 Å²	142	94%	0.936	79%	0.789	S	S	*	*			trans	-152.6	113.7	136.1	-105	165.6	-164.1	-177.5	4.8	109.9
45	S	20.5	Very low	23.9	Very low	108 Å²	108	139.5 Å²	139.5	76%	0.755	78%	0.782	S	S	*	*			trans	-52.5	129.9	162.3	52.2	0	0	0	0	110.5
46	N	26.6	Very low	24.2	Very low	159 Å²	159	141.1 Å²	141.1	85%	0.85	78%	0.783	S	S	*	*			trans	-148.5	129.7	146.7	-95.7	-20.7	0	0	0	109	E48	N46-E48 PolarHBondContact O-N 3.37Å
47	N	23.2	Very low	24.4	Very low	155 Å²	155	144.3 Å²	144.3	83%	0.829	79%	0.793	S	S	*	*			trans	-53	113.2	177.1	-67.2	-33.6	0	0	0	111.1
48	E	25.1	Very low	24.3	Very low	178 Å²	178	145.6 Å²	145.6	83%	0.832	80%	0.799	S	S	*	*			trans	-111.8	90.2	152.1	-78.2	-170.5	160	0	0	108.2	N46 V50	N46-E48 PolarHBondContact O-N 3.37Å; E48-V50 VanDerWaalsContact C-N 3.27Å; E48-V50 PolarHBondContact O-N 3.13Å
49	E	21.8	Very low	24.3	Very low	181 Å²	181	143.5 Å²	143.5	85%	0.846	80%	0.8	S	S	*	*			trans	-60	85.6	161.2	-73.5	178.3	129.6	0	0	109.6	L51	E49-L51 VanDerWaalsContact C-N 3.31Å; E49-L51 PolarHBondContact O-N 3.19Å
50	V	25.7	Very low	24.4	Very low	123 Å²	123	141.4 Å²	141.4	75%	0.745	80%	0.795	S	S	*	*			trans	-90.4	80.9	162.2	-175.3	0	0	0	0	108.5	E48 A52	E48-V50 VanDerWaalsContact C-N 3.27Å; E48-V50 PolarHBondContact O-N 3.13Å; V50-A52 VanDerWaalsContact C-N 3.3Å; V50-A52 PolarHBondContact O-N 3.44Å
51	L	22.6	Very low	24.1	Very low	141 Å²	141	139.9 Å²	139.9	74%	0.738	79%	0.792	S	S	*	*			trans	8.1	63.8	140.9	-133.3	94.7	0	0	0	117.1	E49 T53	E49-L51 VanDerWaalsContact C-N 3.31Å; E49-L51 PolarHBondContact O-N 3.19Å; L51-T53 HydrophobicContact CD2-CG2 3.64Å; L51-T53 HydrophobicContact CG-CG2 3.87Å; L51-T53 PolarHBondContact O-N 2.91Å
52	A	24.5	Very low	24.1	Very low	97 Å²	97	141.5 Å²	141.5	80%	0.802	79%	0.792	S	S	*	*			trans	-75.1	74.8	161.7	0	0	0	0	0	108.1	V50 K54	V50-A52 VanDerWaalsContact C-N 3.3Å; V50-A52 PolarHBondContact O-N 3.44Å; A52-K54 PolarHBondContact O-N 3.49Å
53	T	23.4	Very low	24	Very low	102 Å²	102	140.5 Å²	140.5	63%	0.626	79%	0.79	S	S	*	*			trans	-59.7	113.9	175.1	44.1	0	0	0	0	109	L51 A55	L51-T53 HydrophobicContact CD2-CG2 3.64Å; L51-T53 HydrophobicContact CG-CG2 3.87Å; L51-T53 PolarHBondContact O-N 2.91Å; T53-A55 PolarHBondContact O-N 3.47Å
54	K	22.9	Very low	23.9	Very low	213 Å²	213	142.7 Å²	142.7	93%	0.926	80%	0.795	S	S	*	*			trans	-55.5	85.2	162.6	-76.6	174.1	173.2	174	0	108.9	A52	A52-K54 PolarHBondContact O-N 3.49Å
55	A	24.9	Very low	23.8	Very low	84 Å²	84	137.6 Å²	137.6	69%	0.694	79%	0.791	S	S	*	*			trans	-94.9	134.5	165.7	0	0	0	0	0	108.4	T53	T53-A55 PolarHBondContact O-N 3.47Å
56	D	27.4	Very low	24	Very low	129 Å²	129	135.4 Å²	135.4	69%	0.69	79%	0.785	S	S	*	*	S	Bend	trans	82.2	59.2	-176.1	-73.7	-10.2	0	0	0	117
57	D	27.4	Very low	24.2	Very low	160 Å²	160	137.7 Å²	137.7	86%	0.856	79%	0.788	S	S	*	*			trans	-156	73	145.7	-101.3	-20.6	0	0	0	109.4	P59	D57-P59 VanDerWaalsContact O-CD 3.27Å; D57-P59 WeakPolarHBondContact O-CD 3.47Å
58	Q	22.6	Very low	24.6	Very low	194 Å²	194	136.5 Å²	136.5	91%	0.907	78%	0.781	S	S	*	*			trans	-85	110.5	161	-88.1	-171.3	-17.6	0	0	108	G60	Q58-G60 PolarHBondContact O-N 3.46Å
59	P	25.3	Very low	24.8	Very low	119 Å²	119	132.3 Å²	132.3	77%	0.773	79%	0.786	S	S	*	*			trans	-66.7	119.7	173.2	26.6	-30.7	0	0	0	108.4	D57 L61	D57-P59 VanDerWaalsContact O-CD 3.27Å; D57-P59 WeakPolarHBondContact O-CD 3.47Å; P59-L61 PolarHBondContact O-N 2.95Å
60	G	23	Very low	25.1	Very low	60 Å²	60	129.3 Å²	129.3	62%	0.619	78%	0.78	S	S	*	*			trans	-58.5	120.5	174.3	0	0	0	0	0	110	Q58 V62	Q58-G60 PolarHBondContact O-N 3.46Å; G60-V62 PolarHBondContact O-N 3.12Å; G60-V62 VanDerWaalsContact O-N 3.07Å
61	L	22.6	Very low	25.2	Very low	164 Å²	164	133 Å²	133	86%	0.859	79%	0.786	S	S	*	*			trans	-49.7	112.9	174	-133.8	82.4	0	0	0	109.6	P59	P59-L61 PolarHBondContact O-N 2.95Å
62	V	22.6	Very low	25.4	Very low	126 Å²	126	130.1 Å²	130.1	76%	0.764	78%	0.783	S	S	*	*			trans	-75.1	126.5	173.9	174.8	0	0	0	0	107.5	G60 T64	G60-V62 PolarHBondContact O-N 3.12Å; G60-V62 VanDerWaalsContact O-N 3.07Å; V62-T64 PolarHBondContact O-N 2.96Å
63	C	22.5	Very low	25.4	Very low	123 Å²	123	132.4 Å²	132.4	83%	0.831	78%	0.781	S	S	*	*			trans	-64.2	107.4	173.4	-67.3	0	0	0	0	109
64	T	21.5	Very low	25.5	Very low	133 Å²	133	134.1 Å²	134.1	82%	0.816	79%	0.787	S	S	*	*			trans	-80.4	119.5	165.8	39.5	0	0	0	0	108.5	V62 G66	V62-T64 PolarHBondContact O-N 2.96Å; T64-G66 PolarHBondContact O-N 3.29Å
65	V	24.4	Very low	25.8	Very low	141 Å²	141	131.8 Å²	131.8	86%	0.855	78%	0.783	S	S	*	*			trans	-73	105.7	169	178	0	0	0	0	106.8
66	G	23.4	Very low	25.9	Very low	61 Å²	61	132.2 Å²	132.2	63%	0.629	78%	0.781	S	S	*	*			trans	-61.1	133.6	173.1	0	0	0	0	0	110.2	T64 D68	T64-G66 PolarHBondContact O-N 3.29Å; G66-D68 PolarHBondContact O-N 3.26Å
67	K	31.5	Very low	26	Very low	208 Å²	208	131.1 Å²	131.1	90%	0.904	78%	0.784	S	S	*	*	S	Bend	trans	-73.5	-2.8	-176.6	-100.1	-175.6	174.9	-179.8	0	114.8
68	D	31.9	Very low	26.1	Very low	130 Å²	130	129.9 Å²	129.9	70%	0.695	78%	0.777	S	S	*	*	S	Bend	trans	-110.9	121.7	-178.6	-59	-29.7	0	0	0	108.5	G66 T70	G66-D68 PolarHBondContact O-N 3.26Å; D68-T70 PolarHBondContact O-N 2.86Å; D68-T70 PolarHBondContact O-OG1 2.67Å
69	G	29.1	Very low	26.4	Very low	90 Å²	90	125 Å²	125	93%	0.928	76%	0.762	S	S	*	*			trans	-63.5	24.9	-171.2	0	0	0	0	0	116.6	K71	G69-K71 PolarHBondContact O-N 2.84Å
70	T	27	Very low	26.7	Very low	118 Å²	118	125.7 Å²	125.7	72%	0.724	77%	0.767	S	S	*	*			trans	-83.4	101.3	172.6	15.8	0	0	0	0	109.5	D68 A72	D68-T70 PolarHBondContact O-N 2.86Å; D68-T70 PolarHBondContact O-OG1 2.67Å; T70-A72 VanDerWaalsContact C-N 3.27Å; T70-A72 PolarHBondContact O-N 2.94Å
71	K	28.4	Very low	27.5	Very low	199 Å²	199	126.3 Å²	126.3	87%	0.865	77%	0.773	S	S	*	*			trans	-59.5	90.9	162.5	-76.5	-178	177	177.7	0	108.5	G69 N73	G69-K71 PolarHBondContact O-N 2.84Å; K71-N73 PolarHBondContact O-N 3.29Å
72	A	26.4	Very low	28.3	Very low	82 Å²	82	127.6 Å²	127.6	68%	0.678	77%	0.767	S	S	*	*			trans	-63.1	107.7	166.4	0	0	0	0	0	107.2	T70 N74	T70-A72 VanDerWaalsContact C-N 3.27Å; T70-A72 PolarHBondContact O-N 2.94Å; A72-N74 PolarHBondContact O-N 3.37Å
73	N	25.5	Very low	29.7	Very low	144 Å²	144	124.9 Å²	124.9	77%	0.77	76%	0.757	S	S	*	*			trans	-73.3	42.1	-177.1	-126.4	9.9	0	0	0	111.7	K71 L75	K71-N73 PolarHBondContact O-N 3.29Å; N73-L75 PolarHBondContact O-N 2.95Å
74	N	26.4	Very low	31.4	Very low	139 Å²	139	123.6 Å²	123.6	74%	0.743	75%	0.746	S	S	*	*			trans	-78.1	77.8	168.6	-76.8	-15.8	0	0	0	107.6	A72 S76	A72-N74 PolarHBondContact O-N 3.37Å; N74-S76 PolarHBondContact O-N 3.07Å
75	L	27.2	Very low	33.6	Very low	163 Å²	163	125.4 Å²	125.4	85%	0.853	74%	0.742	S	S	*	*			trans	-66.5	55	157.1	-125.3	81.3	0	0	0	108.4	N73 S77	N73-L75 PolarHBondContact O-N 2.95Å; L75-S77 VanDerWaalsContact C-N 3.26Å; L75-S77 PolarHBondContact O-N 3.43Å
76	S	27.5	Very low	36	Very low	93 Å²	93	119.3 Å²	119.3	65%	0.65	70%	0.704	S	S	*	*			trans	-68.8	98.8	163.8	51.7	0	0	0	0	105.7	N74 N78	N74-S76 PolarHBondContact O-N 3.07Å; S76-N78 PolarHBondContact O-N 2.84Å
77	S	29.5	Very low	38.5	Very low	107 Å²	107	121.7 Å²	121.7	75%	0.748	70%	0.699	S	S	*	*			trans	-13.3	105.1	157.1	45.2	0	0	0	0	111.2	L75 P79	L75-S77 VanDerWaalsContact C-N 3.26Å; L75-S77 PolarHBondContact O-N 3.43Å; S77-P79 WeakPolarHBondContact O-CD 3.32Å
78	N	29.8	Very low	41	Very low	133 Å²	133	117.9 Å²	117.9	71%	0.711	68%	0.679	S	S	*	*			trans	-53.4	120.8	167	-97.2	-50.4	0	0	0	106.1	S76	S76-N78 PolarHBondContact O-N 2.84Å
79	P	29	Very low	43.6	Very low	91 Å²	91	113.1 Å²	113.1	59%	0.591	66%	0.656	S	S	*	*			trans	-56.6	129.8	-179.3	19.3	-29.7	0	0	0	108.4	S77 G81	S77-P79 WeakPolarHBondContact O-CD 3.32Å; P79-G81 PolarHBondContact O-N 3.09Å
80	P	32.3	Very low	46.5	Very low	135 Å²	135	108.9 Å²	108.9	88%	0.877	61%	0.612	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.5	110	-179.4	26.3	-31.5	0	0	0	107.1
81	G	39.7	Very low	49.7	Very low	72 Å²	72	105.5 Å²	105.5	74%	0.742	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	125.1	14.3	178.3	0	0	0	0	0	116.8	P79 A83	P79-G81 PolarHBondContact O-N 3.09Å; G81-A83 PolarHBondContact O-N 3.02Å
82	R	39.3	Very low	52.9	Low	192 Å²	192	98 Å²	98	73%	0.725	56%	0.561	S	S	*	*			trans	-67.6	78.4	161.6	-162	173.3	-172.9	154.5	0.1	108.9	V84	R82-V84 PolarHBondContact O-N 3.45Å
83	A	51.7	Low	56.1	Low	69 Å²	69	99.4 Å²	99.4	57%	0.57	56%	0.556	S	S	*	*			trans	-54.8	115.1	174.1	0	0	0	0	0	107.3	G81 K85	G81-A83 PolarHBondContact O-N 3.02Å; A83-K85 PolarHBondContact O-N 3.26Å
84	V	58.9	Low	59.4	Low	96 Å²	96	93.7 Å²	93.7	58%	0.582	53%	0.525	S	S	*	.			trans	-59.4	115.7	172.7	-177.1	0	0	0	0	106.2	R82 I427	R82-V84 PolarHBondContact O-N 3.45Å; V84-I427 HydrophobicContact CB-CD1 4.26Å; V84-I427 HydrophobicContact CG1-CB 4.31Å; V84-I427 HydrophobicContact CG1-CD1 3.75Å; V84-I427 HydrophobicContact CG1-CG2 4.27Å
85	K	67.2	Low	62.6	Low	170 Å²	170	87 Å²	87	74%	0.739	49%	0.49	S	S	*	.			trans	-105.2	148.4	178.8	-72	178.4	-176.2	177.3	0	108.7	A83	A83-K85 PolarHBondContact O-N 3.26Å
86	L	73.3	Confident	65.9	Low	13 Å²	13	80 Å²	80	7%	0.068	45%	0.454	C	S	.	.			trans	-60.1	137.9	169.5	-66.2	166.8	0	0	0	109.4	E327 R409 F412 I427	L86-E327 HydrophobicContact CB-CG 3.78Å; L86-E327 HydrophobicContact CD1-CG 4.41Å; L86-R409 HydrophobicContact CD1-CG 4.32Å; L86-F412 HydrophobicContact CD1-CD1 4.02Å; L86-F412 HydrophobicContact CD1-CE1 3.79Å; L86-F412 HydrophobicContact CG-CE1 4.17Å; L86-I427 HydrophobicContact CD2-CD1 4.42Å
87	Q	77.5	Confident	69.1	Low	111 Å²	111	75.9 Å²	75.9	52%	0.519	43%	0.425	S	S	.	.			trans	-78.5	137.3	-176.4	-170.4	178.8	15.7	0	0	111	S89 E327	Q87-S89 VanDerWaalsContact C-N 3.3Å; Q87-S89 PolarHBondContact O-N 3.32Å; Q87-E327 WeakPolarHBondContact O-CA 3.29Å
88	R	83.4	Confident	72.2	Confident	129 Å²	129	70.8 Å²	70.8	49%	0.487	39%	0.389	S	S	.	.			trans	-75.2	76.1	173.3	-72.1	-175.9	-177.2	167.9	5.5	112.2	E326 E327 Q329	R88-E326 VanDerWaalsContact CG-O 3.23Å; R88-E326 WeakPolarHBondContact CG-O 3.42Å; R88-E327 CarbonylContact C-O 3.19Å; R88-E327 VanDerWaalsContact CA-O 3.25Å; R88-E327 WeakPolarHBondContact CA-O 3.47Å; R88-Q329 HydrophobicContact CB-CG 4.24Å; R88-Q329 VanDerWaalsContact O-CG 3.29Å; R88-Q329 WeakPolarHBondContact O-CG 3.43Å; R88-Q329 PolarHBondContact O-NE2 3.42Å
89	S	86.3	Confident	75.2	Confident	30 Å²	30	64.4 Å²	64.4	21%	0.21	36%	0.355	C	S	.	.			trans	-99.2	-16.8	-179.3	55.8	0	0	0	0	114.6	Q87 E327	Q87-S89 VanDerWaalsContact C-N 3.3Å; Q87-S89 PolarHBondContact O-N 3.32Å; S89-E327 PolarHBondContact N-O 3.38Å; S89-E327 VanDerWaalsContact N-O 3.09Å
90	I	90.3	Very high	78.4	Confident	1 Å²	1	60.4 Å²	60.4	1%	0.005	33%	0.329	C	S	.	.	B	Isolated β-bridge	trans	-84.6	118.5	-173.6	-58.4	179.1	0	0	0	109.2	N94 I98 T257 I324 E327 L328 Q329	I90-N94 HydrophobicContact CG2-CB 3.73Å; I90-I98 HydrophobicContact CD1-CD1 4.06Å; I90-I98 HydrophobicContact CG2-CD1 4.09Å; I90-T257 HydrophobicContact CG1-CG2 4.31Å; I90-I324 HydrophobicContact CD1-CD1 3.7Å; I90-I324 HydrophobicContact CD1-CG1 4.28Å; I90-E327 WeakPolarHBondContact CB-O 3.37Å; I90-E327 HydrophobicContact CD1-CB 3.76Å; I90-E327 HydrophobicContact CG1-CB 4.1Å; I90-E327 PolarHBondContact N-O 3.46Å; I90-L328 HydrophobicContact CB-CD1 4.35Å; I90-L328 HydrophobicContact CG2-CD1 3.86Å; I90-Q329 WeakPolarHBondContact O-CB 2.93Å; I90-Q329 WeakPolarHBondContact O-CG 3.45Å; I90-Q329 PolarHBondContact O-N 3.05Å
91	T	94.7	Very high	81.3	Confident	47 Å²	47	54 Å²	54	29%	0.288	29%	0.288	S	S	.	.			trans	-81.7	177.3	176.3	78.3	0	0	0	0	111.7	L93 N94 G95	T91-L93 PolarHBondContact OG1-N 2.81Å; T91-N94 PolarHBondContact O-N 2.94Å; T91-N94 PolarHBondContact OG1-N 2.54Å; T91-N94 PolarHBondContact OG1-OD1 3.47Å; T91-G95 PolarHBondContact O-N 3.12Å
92	L	94.8	Very high	83.6	Confident	41 Å²	41	51.1 Å²	51.1	22%	0.215	26%	0.256	C	S	.	.	H	α-helix	trans	-58.1	-47	173	174.8	59.7	0	0	0	112.2	G95 C96 N334 L337 A338	L92-G95 WeakPolarHBondContact O-CA 3.49Å; L92-G95 PolarHBondContact O-N 3.01Å; L92-G95 VanDerWaalsContact O-N 3.09Å; L92-C96 PolarHBondContact O-N 3.45Å; L92-C96 PolarHBondContact O-SG 3.3Å; L92-C96 VanDerWaalsContact O-SG 3.38Å; L92-N334 HydrophobicContact CB-CB 4.31Å; L92-N334 HydrophobicContact CD1-CB 4.12Å; L92-N334 WeakPolarHBondContact CD1-O 3.15Å; L92-L337 HydrophobicContact CD1-CB 3.85Å; L92-L337 HydrophobicContact CD2-CD1 4.32Å; L92-A338 HydrophobicContact CD1-CB 3.99Å
93	L	94.6	Very high	86.1	Confident	111 Å²	111	42.2 Å²	42.2	58%	0.581	22%	0.223	S	C	*	.	H	α-helix	trans	-64.2	-43.4	-178.7	-70.8	176.7	0	0	0	111.2	T91 G95 C96 T97	T91-L93 PolarHBondContact OG1-N 2.81Å; L93-G95 VanDerWaalsContact C-N 3.26Å; L93-G95 PolarHBondContact O-N 3.33Å; L93-C96 WeakPolarHBondContact O-CB 3.33Å; L93-C96 PolarHBondContact O-N 3.03Å; L93-T97 VanDerWaalsContact O-CG2 3.27Å; L93-T97 WeakPolarHBondContact O-CG2 3.44Å; L93-T97 PolarHBondContact O-N 3.31Å; L93-T97 PolarHBondContact O-OG1 2.84Å
94	N	93.2	Very high	88	Confident	24 Å²	24	39 Å²	39	13%	0.128	20%	0.196	C	C	.	.	H	α-helix	trans	-61.3	-36.1	172.8	-65.7	88.8	0	0	0	111.9	I90 T91 T97 I98 D261	I90-N94 HydrophobicContact CG2-CB 3.73Å; T91-N94 PolarHBondContact O-N 2.94Å; T91-N94 PolarHBondContact OG1-N 2.54Å; T91-N94 PolarHBondContact OG1-OD1 3.47Å; N94-T97 VanDerWaalsContact CA-OG1 3.29Å; N94-T97 WeakPolarHBondContact CA-OG1 3.46Å; N94-T97 PolarHBondContact O-OG1 3.04Å; N94-I98 WeakPolarHBondContact O-CB 3.22Å; N94-I98 VanDerWaalsContact O-CD1 3.31Å; N94-I98 WeakPolarHBondContact O-CD1 3.41Å; N94-I98 WeakPolarHBondContact O-CG1 3.31Å; N94-I98 PolarHBondContact O-N 3.02Å; N94-D261 PolarHBondContact ND2-OD1 3.04Å; N94-D261 PolarHBondContact ND2-OD2 3.41Å
95	G	94.7	Very high	89.1	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-63.2	-45.4	174.2	0	0	0	0	0	112.1	T91 L92 L93 I98 I99	T91-G95 PolarHBondContact O-N 3.12Å; L92-G95 WeakPolarHBondContact O-CA 3.49Å; L92-G95 PolarHBondContact O-N 3.01Å; L92-G95 VanDerWaalsContact O-N 3.09Å; L93-G95 VanDerWaalsContact C-N 3.26Å; L93-G95 PolarHBondContact O-N 3.33Å; G95-I98 PolarHBondContact O-N 3.11Å; G95-I99 WeakPolarHBondContact O-CG1 3.41Å; G95-I99 PolarHBondContact O-N 3.21Å; G95-I99 VanDerWaalsContact O-N 3.13Å
96	C	96.1	Very high	89.7	Confident	15 Å²	15	27 Å²	27	10%	0.101	14%	0.138	C	C	.	.	H	α-helix	trans	-61.8	-46.6	175.1	-63.8	0	0	0	0	111.7	L92 L93 I98 I99 V100 S342	L92-C96 PolarHBondContact O-N 3.45Å; L92-C96 PolarHBondContact O-SG 3.3Å; L92-C96 VanDerWaalsContact O-SG 3.38Å; L93-C96 WeakPolarHBondContact O-CB 3.33Å; L93-C96 PolarHBondContact O-N 3.03Å; C96-I98 VanDerWaalsContact C-N 3.31Å; C96-I98 PolarHBondContact O-N 3.41Å; C96-I99 PolarHBondContact O-N 3.49Å; C96-V100 WeakPolarHBondContact O-CB 3.47Å; C96-V100 VanDerWaalsContact O-CG2 3.31Å; C96-V100 WeakPolarHBondContact O-CG2 3.38Å; C96-V100 PolarHBondContact O-N 2.83Å; C96-S342 WeakPolarHBondContact CA-OG 3.41Å; C96-S342 PolarHBondContact O-OG 3.17Å
97	T	95.3	Very high	90.1	Very high	6 Å²	6	26.6 Å²	26.6	4%	0.037	14%	0.137	C	C	.	.	H	α-helix	trans	-65.6	-34.1	-179.3	59.5	0	0	0	0	111.8	L93 N94 G101 D261 T264 Y265	L93-T97 VanDerWaalsContact O-CG2 3.27Å; L93-T97 WeakPolarHBondContact O-CG2 3.44Å; L93-T97 PolarHBondContact O-N 3.31Å; L93-T97 PolarHBondContact O-OG1 2.84Å; N94-T97 VanDerWaalsContact CA-OG1 3.29Å; N94-T97 WeakPolarHBondContact CA-OG1 3.46Å; N94-T97 PolarHBondContact O-OG1 3.04Å; T97-G101 VanDerWaalsContact O-CA 3.25Å; T97-G101 WeakPolarHBondContact O-CA 3.3Å; T97-G101 PolarHBondContact O-N 2.96Å; T97-D261 WeakPolarHBondContact CB-OD1 3.21Å; T97-D261 HydrophobicContact CG2-CB 4.34Å; T97-D261 PolarHBondContact OG1-OD1 3.23Å; T97-T264 PolarHBondContact O-OG1 3.14Å; T97-T264 VanDerWaalsContact O-OG1 3.06Å; T97-Y265 HydrophobicContact CG2-CE1 4.05Å
98	I	93.4	Very high	90.6	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-63.8	-50.2	172.8	-71.5	162.1	0	0	0	110.3	I90 N94 G95 C96 C102 T257 Q260 I324 L405	I90-I98 HydrophobicContact CD1-CD1 4.06Å; I90-I98 HydrophobicContact CG2-CD1 4.09Å; N94-I98 WeakPolarHBondContact O-CB 3.22Å; N94-I98 VanDerWaalsContact O-CD1 3.31Å; N94-I98 WeakPolarHBondContact O-CD1 3.41Å; N94-I98 WeakPolarHBondContact O-CG1 3.31Å; N94-I98 PolarHBondContact O-N 3.02Å; G95-I98 PolarHBondContact O-N 3.11Å; C96-I98 VanDerWaalsContact C-N 3.31Å; C96-I98 PolarHBondContact O-N 3.41Å; I98-C102 VanDerWaalsContact O-CB 3.28Å; I98-C102 WeakPolarHBondContact O-CB 3.45Å; I98-C102 PolarHBondContact O-N 3.03Å; I98-C102 PolarHBondContact O-SG 2.81Å; I98-T257 HydrophobicContact CD1-CG2 4.38Å; I98-Q260 HydrophobicContact CG1-CG 3.9Å; I98-I324 HydrophobicContact CD1-CD1 3.74Å; I98-I324 HydrophobicContact CG2-CD1 4.11Å; I98-L405 HydrophobicContact CD1-CD2 3.93Å; I98-L405 HydrophobicContact CG1-CD2 4.39Å
99	I	94.3	Very high	90.6	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-63.8	-56.3	-179.8	-61.6	172.5	0	0	0	110.4	G95 C96 G101 C102 I103 L321 A338 I339	G95-I99 WeakPolarHBondContact O-CG1 3.41Å; G95-I99 PolarHBondContact O-N 3.21Å; G95-I99 VanDerWaalsContact O-N 3.13Å; C96-I99 PolarHBondContact O-N 3.49Å; I99-G101 VanDerWaalsContact C-N 3.32Å; I99-G101 PolarHBondContact O-N 3.32Å; I99-C102 PolarHBondContact O-N 2.83Å; I99-I103 HydrophobicContact CG2-CD1 3.65Å; I99-I103 HydrophobicContact CG2-CG1 4.4Å; I99-I103 VanDerWaalsContact O-CG1 3.3Å; I99-I103 WeakPolarHBondContact O-CG1 3.44Å; I99-I103 PolarHBondContact O-N 2.96Å; I99-L321 HydrophobicContact CD1-CB 3.73Å; I99-L321 HydrophobicContact CD1-CD2 3.8Å; I99-L321 HydrophobicContact CD1-CG 4.41Å; I99-L321 HydrophobicContact CG1-CB 3.69Å; I99-L321 HydrophobicContact CG1-CD2 4.34Å; I99-A338 HydrophobicContact CD1-CB 4.11Å; I99-I339 HydrophobicContact CD1-CG1 3.92Å
100	V	95.4	Very high	90.2	Very high	7 Å²	7	15.3 Å²	15.3	4%	0.042	9%	0.089	C	C	.	.	H	α-helix	trans	-59.3	-44.8	-178.5	176.8	0	0	0	0	110.8	C96 C102 I103 I104 T264 I268 V346	C96-V100 WeakPolarHBondContact O-CB 3.47Å; C96-V100 VanDerWaalsContact O-CG2 3.31Å; C96-V100 WeakPolarHBondContact O-CG2 3.38Å; C96-V100 PolarHBondContact O-N 2.83Å; V100-C102 VanDerWaalsContact C-N 3.34Å; V100-C102 PolarHBondContact O-N 3.21Å; V100-I103 PolarHBondContact O-N 2.71Å; V100-I104 HydrophobicContact CG1-CD1 3.44Å; V100-I104 VanDerWaalsContact CG1-CD1 3.44Å; V100-I104 HydrophobicContact CG1-CG1 4.11Å; V100-I104 WeakPolarHBondContact O-CB 3.25Å; V100-I104 VanDerWaalsContact O-CG1 3.29Å; V100-I104 WeakPolarHBondContact O-CG1 3.29Å; V100-I104 PolarHBondContact O-N 3.21Å; V100-T264 HydrophobicContact CB-CG2 4.01Å; V100-T264 HydrophobicContact CG1-CG2 3.89Å; V100-I268 HydrophobicContact CG1-CD1 3.87Å; V100-I268 HydrophobicContact CG1-CG1 4.09Å; V100-V346 HydrophobicContact CB-CG2 4.33Å; V100-V346 HydrophobicContact CG1-CG2 3.96Å; V100-V346 HydrophobicContact CG2-CG2 4.14Å
101	G	92.5	Very high	89.9	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-70.2	-26.3	-179.4	0	0	0	0	0	114.2	T97 I99 T264 K267 S399	T97-G101 VanDerWaalsContact O-CA 3.25Å; T97-G101 WeakPolarHBondContact O-CA 3.3Å; T97-G101 PolarHBondContact O-N 2.96Å; I99-G101 VanDerWaalsContact C-N 3.32Å; I99-G101 PolarHBondContact O-N 3.32Å; G101-T264 VanDerWaalsContact CA-OG1 3.3Å; G101-T264 WeakPolarHBondContact CA-OG1 3.37Å; G101-K267 PolarHBondContact O-NZ 3.28Å; G101-S399 PolarHBondContact O-OG 3.36Å
102	C	89.8	Confident	89.7	Confident	11 Å²	11	13.4 Å²	13.4	7%	0.074	8%	0.078	C	C	.	.	H	α-helix	trans	-75.3	-45.2	171.9	-69.4	0	0	0	0	111.2	I98 I99 V100 Y320 S399 G402	I98-C102 VanDerWaalsContact O-CB 3.28Å; I98-C102 WeakPolarHBondContact O-CB 3.45Å; I98-C102 PolarHBondContact O-N 3.03Å; I98-C102 PolarHBondContact O-SG 2.81Å; I99-C102 PolarHBondContact O-N 2.83Å; V100-C102 VanDerWaalsContact C-N 3.34Å; V100-C102 PolarHBondContact O-N 3.21Å; C102-Y320 HydrophobicContact CB-CD1 3.66Å; C102-Y320 HydrophobicContact CB-CE1 4.05Å; C102-Y320 HydrophobicContact CB-CG 4.26Å; C102-Y320 WeakPolarHBondContact SG-CD1 3.08Å; C102-S399 PolarHBondContact O-OG 3.43Å; C102-G402 VanDerWaalsContact SG-CA 3.54Å
103	I	91	Very high	89.3	Confident	6 Å²	6	13.4 Å²	13.4	3%	0.031	8%	0.076	C	C	.	.	H	α-helix	trans	-64.6	-49	179.6	-60	168.3	0	0	0	110.6	I99 V100 G105 A314 N316 W318 V346 Y350	I99-I103 HydrophobicContact CG2-CD1 3.65Å; I99-I103 HydrophobicContact CG2-CG1 4.4Å; I99-I103 VanDerWaalsContact O-CG1 3.3Å; I99-I103 WeakPolarHBondContact O-CG1 3.44Å; I99-I103 PolarHBondContact O-N 2.96Å; V100-I103 PolarHBondContact O-N 2.71Å; I103-G105 PolarHBondContact O-N 3.22Å; I103-A314 WeakPolarHBondContact CG2-O 3.47Å; I103-N316 WeakPolarHBondContact CA-O 3.41Å; I103-W318 HydrophobicContact CD1-CB 4.2Å; I103-V346 HydrophobicContact CB-CG1 4.49Å; I103-V346 HydrophobicContact CB-CG2 4.43Å; I103-V346 HydrophobicContact CD1-CG2 4.33Å; I103-V346 HydrophobicContact CG2-CG1 3.7Å; I103-V346 HydrophobicContact CG2-CG2 4.48Å; I103-Y350 HydrophobicContact CG2-CE2 4.12Å; I103-Y350 PolarHBondContact O-OH 3.25Å
104	I	90.5	Very high	88.8	Confident	0 Å²	0	8.8 Å²	8.8	0%	0	6%	0.055	C	C	.	.	S	Bend	trans	-73.1	79.4	174.2	-52.6	176.9	0	0	0	109.5	V100 K267 I268 L271 V346 Y350 S395 S399	V100-I104 HydrophobicContact CG1-CD1 3.44Å; V100-I104 VanDerWaalsContact CG1-CD1 3.44Å; V100-I104 HydrophobicContact CG1-CG1 4.11Å; V100-I104 WeakPolarHBondContact O-CB 3.25Å; V100-I104 VanDerWaalsContact O-CG1 3.29Å; V100-I104 WeakPolarHBondContact O-CG1 3.29Å; V100-I104 PolarHBondContact O-N 3.21Å; I104-K267 HydrophobicContact CB-CD 4.24Å; I104-K267 HydrophobicContact CG2-CB 4Å; I104-K267 HydrophobicContact CG2-CD 4.06Å; I104-K267 HydrophobicContact CG2-CG 4.36Å; I104-K267 VanDerWaalsContact O-CD 3.31Å; I104-K267 WeakPolarHBondContact O-CD 3.44Å; I104-K267 PolarHBondContact O-NZ 3.5Å; I104-I268 HydrophobicContact CD1-CG1 4.2Å; I104-L271 HydrophobicContact CD1-CD1 3.92Å; I104-L271 HydrophobicContact CG1-CD1 4.4Å; I104-L271 HydrophobicContact CG2-CD1 3.69Å; I104-V346 HydrophobicContact CD1-CG2 4.39Å; I104-V346 HydrophobicContact CG1-CG2 4.25Å; I104-Y350 WeakPolarHBondContact CA-OH 3.48Å; I104-Y350 HydrophobicContact CG1-CE1 3.9Å; I104-S395 PolarHBondContact O-OG 2.91Å; I104-S399 PolarHBondContact O-OG 2.93Å; I104-S399 VanDerWaalsContact O-OG 3.11Å
105	G	83.5	Confident	88.7	Confident	4 Å²	4	7.7 Å²	7.7	4%	0.041	5%	0.049	C	C	.	.	S	Bend	trans	-109.3	-129.6	170.1	0	0	0	0	0	111.6	I103 F109 S395 S399	I103-G105 PolarHBondContact O-N 3.22Å; G105-F109 VanDerWaalsContact O-CD2 3.27Å; G105-F109 WeakPolarHBondContact O-CD2 3.37Å; G105-F109 WeakPolarHBondContact O-CE2 3.45Å; G105-S395 PolarHBondContact O-OG 3.19Å; G105-S399 WeakPolarHBondContact CA-OG 3.43Å; G105-S399 PolarHBondContact N-OG 3.29Å
106	S	78.2	Confident	88.6	Confident	11 Å²	11	8.2 Å²	8.2	8%	0.077	5%	0.051	C	C	.	.	S	Bend	trans	-79.9	-19.5	171.9	51.3	0	0	0	0	113.2	I108 F109 V110	S106-I108 PolarHBondContact O-N 3.25Å; S106-F109 PolarHBondContact O-N 3.38Å; S106-V110 PolarHBondContact O-N 3.11Å
107	G	81.8	Confident	88.3	Confident	4 Å²	4	12.1 Å²	12.1	4%	0.041	7%	0.068	C	C	.	.	H	α-helix	trans	-50.7	-54.1	-171.1	0	0	0	0	0	113.9	F109 V110 S111	G107-F109 PolarHBondContact O-N 3.04Å; G107-V110 PolarHBondContact O-N 2.95Å; G107-S111 WeakPolarHBondContact O-CB 3.11Å; G107-S111 PolarHBondContact O-N 2.79Å; G107-S111 PolarHBondContact O-OG 2.93Å
108	I	88.4	Confident	87.9	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-66.1	-22	-179	-170.3	55.8	0	0	0	114.2	S106 P112 W129 L271 Y350 T353 N354	S106-I108 PolarHBondContact O-N 3.25Å; I108-P112 WeakPolarHBondContact O-CD 3.37Å; I108-P112 WeakPolarHBondContact O-CG 3.19Å; I108-W129 HydrophobicContact CD1-CE3 4.43Å; I108-W129 HydrophobicContact CD1-CH2 3.56Å; I108-W129 HydrophobicContact CD1-CZ2 4.1Å; I108-W129 HydrophobicContact CD1-CZ3 3.76Å; I108-L271 HydrophobicContact CG2-CD2 4.3Å; I108-Y350 HydrophobicContact CB-CD1 3.94Å; I108-Y350 HydrophobicContact CB-CE1 3.48Å; I108-Y350 VanDerWaalsContact CB-CE1 3.48Å; I108-Y350 HydrophobicContact CB-CE2 4.31Å; I108-Y350 HydrophobicContact CD1-CD1 3.67Å; I108-Y350 HydrophobicContact CD1-CD2 4.14Å; I108-Y350 HydrophobicContact CD1-CE1 4.14Å; I108-Y350 HydrophobicContact CD1-CG 3.64Å; I108-Y350 HydrophobicContact CG1-CD1 3.58Å; I108-Y350 HydrophobicContact CG1-CE1 3.67Å; I108-Y350 HydrophobicContact CG1-CG 4.1Å; I108-Y350 HydrophobicContact CG2-CE1 3.82Å; I108-T353 HydrophobicContact CG1-CG2 4.12Å; I108-N354 WeakPolarHBondContact CD1-ND2 3.18Å
109	F	83.6	Confident	87.8	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-89.4	-20.1	-177.5	-54.5	-62	0	0	0	113.3	G105 S106 G107 L271 I274 T372 A373 F391 V392	G105-F109 VanDerWaalsContact O-CD2 3.27Å; G105-F109 WeakPolarHBondContact O-CD2 3.37Å; G105-F109 WeakPolarHBondContact O-CE2 3.45Å; S106-F109 PolarHBondContact O-N 3.38Å; G107-F109 PolarHBondContact O-N 3.04Å; F109-L271 HydrophobicContact CE1-CD2 3.6Å; F109-L271 HydrophobicContact CZ-CD2 3.9Å; F109-L271 HydrophobicContact CZ-CG 4.46Å; F109-I274 HydrophobicContact CE1-CD1 4.46Å; F109-T372 PolarHBondContact O-N 3.11Å; F109-A373 HydrophobicContact CB-CB 4.13Å; F109-A373 HydrophobicContact CD1-CB 3.74Å; F109-A373 HydrophobicContact CG-CB 4.32Å; F109-F391 HydrophobicContact CE1-CD1 4.39Å; F109-F391 AromaticContact CE1-CE1 3.72Å; F109-F391 HydrophobicContact CE1-CE1 3.72Å; F109-F391 HydrophobicContact CE2-CE1 4.39Å; F109-F391 HydrophobicContact CZ-CD1 4.19Å; F109-F391 AromaticContact CZ-CE1 3.38Å; F109-F391 HydrophobicContact CZ-CE1 3.38Å; F109-F391 HydrophobicContact CZ-CZ 4.03Å; F109-V392 HydrophobicContact CB-CG1 4.38Å; F109-V392 HydrophobicContact CB-CG2 4.27Å; F109-V392 HydrophobicContact CD1-CG2 4.02Å; F109-V392 HydrophobicContact CD2-CB 4.37Å; F109-V392 HydrophobicContact CD2-CG1 3.86Å; F109-V392 HydrophobicContact CD2-CG2 3.91Å; F109-V392 HydrophobicContact CE1-CG2 4.33Å; F109-V392 HydrophobicContact CE2-CG1 4.49Å; F109-V392 HydrophobicContact CE2-CG2 4.24Å; F109-V392 HydrophobicContact CG-CG1 4.26Å; F109-V392 HydrophobicContact CG-CG2 3.8Å; F109-V392 HydrophobicContact CZ-CG2 4.45Å
110	V	77.9	Confident	87.7	Confident	33 Å²	33	17 Å²	17	20%	0.2	10%	0.096	C	C	.	.	H	α-helix	trans	-114.3	-41.3	-175.4	-180	0	0	0	0	112.1	S106 G107	S106-V110 PolarHBondContact O-N 3.11Å; G107-V110 PolarHBondContact O-N 2.95Å
111	S	84.8	Confident	87.6	Confident	9 Å²	9	16.7 Å²	16.7	6%	0.063	10%	0.095	C	C	.	.	H	α-helix	trans	-64.3	-25.8	-175.2	-46.4	0	0	0	0	115.6	G107 K113 G114 V115 S310	G107-S111 WeakPolarHBondContact O-CB 3.11Å; G107-S111 PolarHBondContact O-N 2.79Å; G107-S111 PolarHBondContact O-OG 2.93Å; S111-K113 PolarHBondContact O-N 3.23Å; S111-G114 PolarHBondContact O-N 3.37Å; S111-G114 VanDerWaalsContact O-N 3.14Å; S111-V115 WeakPolarHBondContact O-CG2 3.48Å; S111-V115 PolarHBondContact O-N 3.12Å; S111-S310 WeakPolarHBondContact CB-O 3.42Å; S111-S310 PolarHBondContact OG-O 2.9Å
112	P	89.1	Confident	87.6	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-52.9	-39.7	178.4	-30.3	37	0	0	0	113.7	I108 V115 H116 W129 N354 F357 F366 T372	I108-P112 WeakPolarHBondContact O-CD 3.37Å; I108-P112 WeakPolarHBondContact O-CG 3.19Å; P112-V115 PolarHBondContact O-N 3.2Å; P112-H116 WeakPolarHBondContact O-CB 3.46Å; P112-H116 PolarHBondContact O-N 2.92Å; P112-W129 HydrophobicContact CG-CZ2 4.01Å; P112-N354 WeakPolarHBondContact CB-OD1 3.49Å; P112-N354 WeakPolarHBondContact CG-OD1 3.33Å; P112-F357 HydrophobicContact CB-CD2 4.39Å; P112-F357 HydrophobicContact CG-CD2 4.08Å; P112-F357 HydrophobicContact CG-CE2 3.99Å; P112-F366 HydrophobicContact CB-CE1 3.51Å; P112-F366 HydrophobicContact CB-CZ 3.93Å; P112-T372 HydrophobicContact CB-CG2 4.2Å
113	K	86.7	Confident	87.9	Confident	41 Å²	41	16.8 Å²	16.8	18%	0.178	10%	0.096	C	C	.	.	H	α-helix	trans	-57.6	-55.6	175.1	168.7	170	164.9	171.2	0	111.3	S111 V115 H116 E117 L367 T369 D370	S111-K113 PolarHBondContact O-N 3.23Å; K113-V115 VanDerWaalsContact C-N 3.31Å; K113-V115 PolarHBondContact O-N 2.96Å; K113-H116 PolarHBondContact O-N 3.05Å; K113-H116 VanDerWaalsContact O-N 3.15Å; K113-E117 VanDerWaalsContact O-CB 3.32Å; K113-E117 WeakPolarHBondContact O-CB 3.42Å; K113-E117 PolarHBondContact O-N 2.97Å; K113-L367 WeakPolarHBondContact CE-O 3.26Å; K113-L367 PolarHBondContact NZ-O 3.38Å; K113-T369 WeakPolarHBondContact CD-O 3.47Å; K113-D370 IonicContact NZ-OD1 2.73Å; K113-D370 PolarHBondContact NZ-OD1 3.43Å
114	G	84.7	Confident	88.1	Confident	13 Å²	13	17.7 Å²	17.7	13%	0.134	10%	0.101	C	C	.	.	H	α-helix	trans	-61.9	-38.3	-179	0	0	0	0	0	112.7	S111 Y118	S111-G114 PolarHBondContact O-N 3.37Å; S111-G114 VanDerWaalsContact O-N 3.14Å; G114-Y118 WeakPolarHBondContact O-CD2 3.4Å; G114-Y118 PolarHBondContact O-N 2.61Å
115	V	90.9	Very high	88.3	Confident	1 Å²	1	17.7 Å²	17.7	1%	0.006	10%	0.101	C	C	.	.	H	α-helix	trans	-63.6	-45.8	175.2	-179.1	0	0	0	0	110.7	S111 P112 K113 S119 S125 L128 W129	S111-V115 WeakPolarHBondContact O-CG2 3.48Å; S111-V115 PolarHBondContact O-N 3.12Å; P112-V115 PolarHBondContact O-N 3.2Å; K113-V115 VanDerWaalsContact C-N 3.31Å; K113-V115 PolarHBondContact O-N 2.96Å; V115-S119 WeakPolarHBondContact O-CB 3.33Å; V115-S119 PolarHBondContact O-N 2.95Å; V115-S119 PolarHBondContact O-OG 3.42Å; V115-S125 WeakPolarHBondContact CG1-OG 3.28Å; V115-L128 HydrophobicContact CG1-CB 4.35Å; V115-L128 HydrophobicContact CG1-CD1 4.5Å; V115-W129 HydrophobicContact CG2-CZ2 4.14Å
116	H	92.3	Very high	88.9	Confident	11 Å²	11	18.9 Å²	18.9	5%	0.051	11%	0.106	C	C	.	.	H	α-helix	trans	-66.1	-46.1	-179.8	-170.5	63.5	0	0	0	112.8	P112 K113 Y118 S119 G120 Y358 A363 F366	P112-H116 WeakPolarHBondContact O-CB 3.46Å; P112-H116 PolarHBondContact O-N 2.92Å; K113-H116 PolarHBondContact O-N 3.05Å; K113-H116 VanDerWaalsContact O-N 3.15Å; H116-Y118 VanDerWaalsContact C-N 3.33Å; H116-Y118 PolarHBondContact O-N 3.38Å; H116-S119 WeakPolarHBondContact CA-OG 3.05Å; H116-S119 PolarHBondContact O-N 3.36Å; H116-S119 PolarHBondContact O-OG 3.28Å; H116-G120 PolarHBondContact O-N 2.81Å; H116-Y358 VanDerWaalsContact CB-OH 3.3Å; H116-Y358 WeakPolarHBondContact CB-OH 3.43Å; H116-Y358 AromaticContact CE1-CE1 3.98Å; H116-Y358 VanDerWaalsContact CG-OH 3.32Å; H116-Y358 AromaticContact ND1-CE1 3.62Å; H116-Y358 AromaticContact ND1-CZ 3.64Å; H116-Y358 PolarHBondContact ND1-OH 3.48Å; H116-A363 PolarHBondContact NE2-O 2.9Å; H116-F366 HydrophobicContact CB-CD1 3.91Å; H116-F366 HydrophobicContact CB-CE1 4.41Å
117	E	89.7	Confident	89.7	Confident	97 Å²	97	22.6 Å²	22.6	45%	0.453	13%	0.125	S	C	.	.	H	α-helix	trans	-53.2	-50	-179.7	-176.1	175.2	-177.8	0	0	111.5	K113 L367	K113-E117 VanDerWaalsContact O-CB 3.32Å; K113-E117 WeakPolarHBondContact O-CB 3.42Å; K113-E117 PolarHBondContact O-N 2.97Å; E117-L367 HydrophobicContact CB-CD2 3.59Å; E117-L367 HydrophobicContact CG-CD2 4.02Å
118	Y	88.1	Confident	90.4	Very high	76 Å²	76	23.1 Å²	23.1	30%	0.298	13%	0.126	S	C	.	.	H	α-helix	trans	-83.6	-25.8	-179.9	-64	-62.4	0	0	0	113.3	G114 H116 G120 S298 D303 L306	G114-Y118 WeakPolarHBondContact O-CD2 3.4Å; G114-Y118 PolarHBondContact O-N 2.61Å; H116-Y118 VanDerWaalsContact C-N 3.33Å; H116-Y118 PolarHBondContact O-N 3.38Å; Y118-G120 VanDerWaalsContact C-N 3.33Å; Y118-S298 WeakPolarHBondContact O-CB 3.26Å; Y118-D303 WeakPolarHBondContact CB-O 3.23Å; Y118-D303 WeakPolarHBondContact O-CB 3.33Å; Y118-L306 HydrophobicContact CD1-CB 3.87Å; Y118-L306 HydrophobicContact CD1-CD1 3.95Å; Y118-L306 HydrophobicContact CD2-CB 3.7Å; Y118-L306 HydrophobicContact CE1-CB 4.08Å; Y118-L306 HydrophobicContact CE1-CD1 3.6Å; Y118-L306 HydrophobicContact CE1-CG 4.48Å; Y118-L306 HydrophobicContact CE2-CB 3.95Å; Y118-L306 HydrophobicContact CG-CB 3.7Å
119	S	91.4	Very high	90.7	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-75	-25.7	174.4	66.6	0	0	0	0	112.8	V115 H116 S121 S125 S298	V115-S119 WeakPolarHBondContact O-CB 3.33Å; V115-S119 PolarHBondContact O-N 2.95Å; V115-S119 PolarHBondContact O-OG 3.42Å; H116-S119 WeakPolarHBondContact CA-OG 3.05Å; H116-S119 PolarHBondContact O-N 3.36Å; H116-S119 PolarHBondContact O-OG 3.28Å; S119-S121 PolarHBondContact O-N 3.45Å; S119-S121 PolarHBondContact OG-O 3.03Å; S119-S125 WeakPolarHBondContact OG-CB 3.44Å; S119-S125 PolarHBondContact OG-N 3.42Å; S119-S298 PolarHBondContact O-N 3.24Å
120	G	91.2	Very high	91.4	Very high	32 Å²	32	26.5 Å²	26.5	33%	0.33	15%	0.147	S	C	.	.			trans	70.8	-17	-177.2	0	0	0	0	0	115.1	H116 Y118 G296	H116-G120 PolarHBondContact O-N 2.81Å; Y118-G120 VanDerWaalsContact C-N 3.33Å; G120-G296 CarbonylContact C-O 3.39Å; G120-G296 WeakPolarHBondContact CA-O 3.39Å; G120-G296 CarbonylContact O-C 3.55Å
121	S	93.2	Very high	92.2	Very high	2 Å²	2	29.4 Å²	29.4	1%	0.014	16%	0.157	C	C	.	.	S	Bend	trans	-138.6	158	-178.8	76.7	0	0	0	0	113.8	S119 L124 S125 P293 E295 T297	S119-S121 PolarHBondContact O-N 3.45Å; S119-S121 PolarHBondContact OG-O 3.03Å; S121-L124 WeakPolarHBondContact OG-CB 3.37Å; S121-L124 PolarHBondContact OG-N 3.44Å; S121-S125 VanDerWaalsContact O-CB 3.29Å; S121-S125 WeakPolarHBondContact O-CB 3.5Å; S121-S125 PolarHBondContact O-N 3.45Å; S121-S125 VanDerWaalsContact O-N 3.12Å; S121-P293 VanDerWaalsContact CB-O 3.31Å; S121-P293 WeakPolarHBondContact CB-O 3.47Å; S121-E295 WeakPolarHBondContact CB-O 3.23Å; S121-T297 WeakPolarHBondContact CB-OG1 3.49Å; S121-T297 PolarHBondContact OG-OG1 3.01Å
122	V	94	Very high	92.6	Very high	6 Å²	6	29 Å²	29	4%	0.036	15%	0.154	C	C	.	.	H	α-helix	trans	-68	-43.6	178.6	177	0	0	0	0	110.9	S125 L126 S289 F290 P293 Y358 A363	V122-S125 WeakPolarHBondContact O-CB 3.17Å; V122-S125 PolarHBondContact O-N 2.83Å; V122-L126 HydrophobicContact CG1-CD1 4.29Å; V122-L126 WeakPolarHBondContact O-CG 3.43Å; V122-L126 PolarHBondContact O-N 3.21Å; V122-S289 WeakPolarHBondContact CG2-O 3.16Å; V122-F290 HydrophobicContact CG1-CD1 4.08Å; V122-F290 HydrophobicContact CG1-CE1 3.76Å; V122-P293 HydrophobicContact CB-CB 4.47Å; V122-P293 PolarHBondContact N-O 2.89Å; V122-Y358 HydrophobicContact CB-CE1 4.49Å; V122-Y358 HydrophobicContact CG1-CD1 4.07Å; V122-Y358 HydrophobicContact CG1-CD2 3.68Å; V122-Y358 HydrophobicContact CG1-CE1 4.35Å; V122-Y358 HydrophobicContact CG1-CE2 3.98Å; V122-Y358 HydrophobicContact CG1-CG 3.71Å; V122-Y358 HydrophobicContact CG2-CD1 3.81Å; V122-Y358 HydrophobicContact CG2-CE1 3.82Å; V122-Y358 HydrophobicContact CG2-CG 4.32Å; V122-A363 HydrophobicContact CG2-CB 3.85Å
123	G	94.2	Very high	92.9	Very high	7 Å²	7	29 Å²	29	7%	0.072	16%	0.155	C	C	.	.	H	α-helix	trans	-63	-48	-178.5	0	0	0	0	0	112	L126 I127 P293	G123-L126 PolarHBondContact O-N 2.6Å; G123-I127 VanDerWaalsContact O-CG1 3.3Å; G123-I127 WeakPolarHBondContact O-CG1 3.43Å; G123-I127 PolarHBondContact O-N 3.28Å; G123-I127 VanDerWaalsContact O-N 3.08Å; G123-P293 PolarHBondContact N-O 3.04Å
124	L	95.1	Very high	93.4	Very high	24 Å²	24	32.7 Å²	32.7	13%	0.126	17%	0.171	C	C	.	.	H	α-helix	trans	-66.5	-41.5	176	-177.6	60.4	0	0	0	111	S121 L126 I127 L128 T297 I304	S121-L124 WeakPolarHBondContact OG-CB 3.37Å; S121-L124 PolarHBondContact OG-N 3.44Å; L124-L126 VanDerWaalsContact C-N 3.33Å; L124-L126 PolarHBondContact O-N 3.35Å; L124-I127 PolarHBondContact O-N 2.82Å; L124-L128 HydrophobicContact CD1-CD1 4.44Å; L124-L128 HydrophobicContact CD1-CD2 4.28Å; L124-L128 HydrophobicContact CD1-CG 4.07Å; L124-L128 HydrophobicContact CG-CD1 4.08Å; L124-L128 HydrophobicContact CG-CG 4.17Å; L124-L128 VanDerWaalsContact O-CG 3.27Å; L124-L128 WeakPolarHBondContact O-CG 3.43Å; L124-L128 PolarHBondContact O-N 3.25Å; L124-T297 HydrophobicContact CB-CG2 3.99Å; L124-T297 HydrophobicContact CD2-CG2 3.67Å; L124-T297 HydrophobicContact CG-CG2 4.38Å; L124-I304 HydrophobicContact CD2-CG1 4.39Å
125	S	95.1	Very high	93.8	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-52.3	-49.5	175.1	-176	0	0	0	0	112	V115 S119 S121 V122 L128 W129 Y358	V115-S125 WeakPolarHBondContact CG1-OG 3.28Å; S119-S125 WeakPolarHBondContact OG-CB 3.44Å; S119-S125 PolarHBondContact OG-N 3.42Å; S121-S125 VanDerWaalsContact O-CB 3.29Å; S121-S125 WeakPolarHBondContact O-CB 3.5Å; S121-S125 PolarHBondContact O-N 3.45Å; S121-S125 VanDerWaalsContact O-N 3.12Å; V122-S125 WeakPolarHBondContact O-CB 3.17Å; V122-S125 PolarHBondContact O-N 2.83Å; S125-L128 PolarHBondContact O-N 2.75Å; S125-W129 PolarHBondContact O-N 3.46Å; S125-Y358 WeakPolarHBondContact CB-OH 3.4Å; S125-Y358 PolarHBondContact OG-OH 2.88Å
126	L	96.2	Very high	94	Very high	29 Å²	29	32.7 Å²	32.7	15%	0.152	17%	0.167	C	C	.	.	H	α-helix	trans	-65.4	-40.3	178.9	-68.1	178.5	0	0	0	112.8	V122 G123 L124 L128 W129 V130 F290 N354 I355 Y358	V122-L126 HydrophobicContact CG1-CD1 4.29Å; V122-L126 WeakPolarHBondContact O-CG 3.43Å; V122-L126 PolarHBondContact O-N 3.21Å; G123-L126 PolarHBondContact O-N 2.6Å; L124-L126 VanDerWaalsContact C-N 3.33Å; L124-L126 PolarHBondContact O-N 3.35Å; L126-L128 VanDerWaalsContact C-N 3.3Å; L126-L128 PolarHBondContact O-N 3.08Å; L126-W129 PolarHBondContact O-N 3.03Å; L126-V130 WeakPolarHBondContact O-CG2 3.16Å; L126-V130 PolarHBondContact O-N 3.23Å; L126-V130 VanDerWaalsContact O-N 3.1Å; L126-F290 HydrophobicContact CD1-CE1 4.1Å; L126-N354 HydrophobicContact CD2-CB 3.78Å; L126-I355 HydrophobicContact CD1-CG1 3.89Å; L126-I355 HydrophobicContact CD2-CG1 3.78Å; L126-Y358 HydrophobicContact CD2-CD2 4.24Å; L126-Y358 HydrophobicContact CD2-CE2 4.28Å; L126-Y358 HydrophobicContact CG-CE2 4.46Å
127	I	96.4	Very high	94.1	Very high	90 Å²	90	33.8 Å²	33.8	46%	0.462	18%	0.179	S	C	.	.	H	α-helix	trans	-59.8	-43.4	174.1	-69.9	168.2	0	0	0	110.4	G123 L124 W129 V130 F131 F294	G123-I127 VanDerWaalsContact O-CG1 3.3Å; G123-I127 WeakPolarHBondContact O-CG1 3.43Å; G123-I127 PolarHBondContact O-N 3.28Å; G123-I127 VanDerWaalsContact O-N 3.08Å; L124-I127 PolarHBondContact O-N 2.82Å; I127-W129 VanDerWaalsContact C-N 3.34Å; I127-W129 PolarHBondContact O-N 2.72Å; I127-V130 PolarHBondContact O-N 3.05Å; I127-F131 VanDerWaalsContact O-CB 3.29Å; I127-F131 WeakPolarHBondContact O-CB 3.29Å; I127-F131 PolarHBondContact O-N 2.73Å; I127-F294 HydrophobicContact CD1-CE1 3.8Å; I127-F294 HydrophobicContact CD1-CZ 4.05Å
128	L	94.7	Very high	94.4	Very high	14 Å²	14	29.8 Å²	29.8	7%	0.073	16%	0.16	C	C	.	.	H	α-helix	trans	-66.8	-34.1	179.1	-65.9	179.3	0	0	0	112.3	V115 L124 S125 L126 G132 I304 A307 L308	V115-L128 HydrophobicContact CG1-CB 4.35Å; V115-L128 HydrophobicContact CG1-CD1 4.5Å; L124-L128 HydrophobicContact CD1-CD1 4.44Å; L124-L128 HydrophobicContact CD1-CD2 4.28Å; L124-L128 HydrophobicContact CD1-CG 4.07Å; L124-L128 HydrophobicContact CG-CD1 4.08Å; L124-L128 HydrophobicContact CG-CG 4.17Å; L124-L128 VanDerWaalsContact O-CG 3.27Å; L124-L128 WeakPolarHBondContact O-CG 3.43Å; L124-L128 PolarHBondContact O-N 3.25Å; S125-L128 PolarHBondContact O-N 2.75Å; L126-L128 VanDerWaalsContact C-N 3.3Å; L126-L128 PolarHBondContact O-N 3.08Å; L128-G132 PolarHBondContact O-N 2.91Å; L128-I304 HydrophobicContact CD2-CG2 4.38Å; L128-A307 HydrophobicContact CD1-CB 3.41Å; L128-A307 VanDerWaalsContact CD1-CB 3.41Å; L128-L308 HydrophobicContact CD2-CD2 3.66Å; L128-L308 HydrophobicContact CD2-CG 3.96Å
129	W	96.1	Very high	94.7	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-63.6	-44.2	172.1	-83.9	106.6	0	0	0	112.5	I108 P112 V115 S125 L126 I127 G133 A314 Y315 Y350 N354	I108-W129 HydrophobicContact CD1-CE3 4.43Å; I108-W129 HydrophobicContact CD1-CH2 3.56Å; I108-W129 HydrophobicContact CD1-CZ2 4.1Å; I108-W129 HydrophobicContact CD1-CZ3 3.76Å; P112-W129 HydrophobicContact CG-CZ2 4.01Å; V115-W129 HydrophobicContact CG2-CZ2 4.14Å; S125-W129 PolarHBondContact O-N 3.46Å; L126-W129 PolarHBondContact O-N 3.03Å; I127-W129 VanDerWaalsContact C-N 3.34Å; I127-W129 PolarHBondContact O-N 2.72Å; W129-G133 PolarHBondContact O-N 3.31Å; W129-G133 VanDerWaalsContact O-N 3.17Å; W129-A314 HydrophobicContact CH2-CB 3.59Å; W129-A314 HydrophobicContact CZ3-CB 3.69Å; W129-Y315 AromaticContact CE3-CE2 3.68Å; W129-Y315 HydrophobicContact CE3-CE2 3.68Å; W129-Y315 HydrophobicContact CZ3-CE2 4.01Å; W129-Y315 WeakPolarHBondContact O-CE2 3.49Å; W129-Y315 PolarHBondContact O-OH 2.63Å; W129-Y350 HydrophobicContact CE3-CD2 4.06Å; W129-Y350 HydrophobicContact CE3-CG 4.45Å; W129-Y350 AromaticContact CZ3-CD2 3.54Å; W129-Y350 HydrophobicContact CZ3-CD2 3.54Å; W129-Y350 HydrophobicContact CZ3-CE2 4.17Å; W129-Y350 HydrophobicContact CZ3-CG 4.13Å; W129-N354 VanDerWaalsContact CD2-ND2 3.29Å; W129-N354 PolarHBondContact NE1-ND2 3.3Å; W129-N354 PolarHBondContact NE1-OD1 2.78Å
130	V	97.1	Very high	94.8	Very high	71 Å²	71	26.2 Å²	26.2	43%	0.43	15%	0.146	S	C	.	.	H	α-helix	trans	-66.5	-46.3	176.5	175	0	0	0	0	110.6	L126 I127 G132 G133 F134 T351	L126-V130 WeakPolarHBondContact O-CG2 3.16Å; L126-V130 PolarHBondContact O-N 3.23Å; L126-V130 VanDerWaalsContact O-N 3.1Å; I127-V130 PolarHBondContact O-N 3.05Å; V130-G132 VanDerWaalsContact C-N 3.35Å; V130-G132 PolarHBondContact O-N 2.79Å; V130-G133 PolarHBondContact O-N 2.96Å; V130-F134 PolarHBondContact O-N 3.36Å; V130-T351 HydrophobicContact CG2-CG2 3.65Å
131	F	95.1	Very high	95	Very high	94 Å²	94	29 Å²	29	41%	0.412	15%	0.148	S	C	.	.	H	α-helix	trans	-61.1	-43.2	177.9	177.1	-92.6	0	0	0	111.6	I127 G133 F134 F135 L308	I127-F131 VanDerWaalsContact O-CB 3.29Å; I127-F131 WeakPolarHBondContact O-CB 3.29Å; I127-F131 PolarHBondContact O-N 2.73Å; F131-G133 VanDerWaalsContact C-N 3.31Å; F131-G133 PolarHBondContact O-N 3.02Å; F131-F134 PolarHBondContact O-N 2.65Å; F131-F135 HydrophobicContact CE1-CB 4.44Å; F131-F135 WeakPolarHBondContact O-CB 3.14Å; F131-F135 PolarHBondContact O-N 3.27Å; F131-L308 HydrophobicContact CD1-CD2 3.4Å; F131-L308 VanDerWaalsContact CD1-CD2 3.4Å; F131-L308 HydrophobicContact CE1-CD1 4.32Å; F131-L308 HydrophobicContact CE1-CD2 3.7Å
132	G	93.9	Very high	95	Very high	1 Å²	1	28.9 Å²	28.9	1%	0.01	15%	0.147	C	C	.	.	H	α-helix	trans	-59.5	-41.7	176.4	0	0	0	0	0	112.4	L128 V130 F135 A136	L128-G132 PolarHBondContact O-N 2.91Å; V130-G132 VanDerWaalsContact C-N 3.35Å; V130-G132 PolarHBondContact O-N 2.79Å; G132-F135 PolarHBondContact O-N 3.07Å; G132-A136 WeakPolarHBondContact O-CB 3.33Å; G132-A136 PolarHBondContact O-N 3.12Å
133	G	95.7	Very high	95.1	Very high	1 Å²	1	28.6 Å²	28.6	1%	0.01	15%	0.145	C	C	.	.	H	α-helix	trans	-65.7	-43.3	174.9	0	0	0	0	0	113	W129 V130 F131 A136 A137 Y315 T347	W129-G133 PolarHBondContact O-N 3.31Å; W129-G133 VanDerWaalsContact O-N 3.17Å; V130-G133 PolarHBondContact O-N 2.96Å; F131-G133 VanDerWaalsContact C-N 3.31Å; F131-G133 PolarHBondContact O-N 3.02Å; G133-A136 PolarHBondContact O-N 3.29Å; G133-A137 WeakPolarHBondContact O-CB 3.41Å; G133-A137 PolarHBondContact O-N 3.5Å; G133-Y315 VanDerWaalsContact CA-CZ 3.49Å; G133-T347 VanDerWaalsContact CA-OG1 3.29Å; G133-T347 WeakPolarHBondContact CA-OG1 3.46Å
134	F	95.6	Very high	95.1	Very high	118 Å²	118	28.4 Å²	28.4	52%	0.518	14%	0.142	S	C	.	.	H	α-helix	trans	-63	-43.2	174.3	-178.5	-103.7	0	0	0	112.1	V130 F131 A137 L138	V130-F134 PolarHBondContact O-N 3.36Å; F131-F134 PolarHBondContact O-N 2.65Å; F134-A137 WeakPolarHBondContact O-CB 3.49Å; F134-A137 PolarHBondContact O-N 3.37Å; F134-L138 HydrophobicContact CD1-CD1 4.03Å; F134-L138 HydrophobicContact CD1-CG 4.3Å; F134-L138 HydrophobicContact CE1-CD1 3.55Å; F134-L138 HydrophobicContact CE1-CD2 4.34Å; F134-L138 HydrophobicContact CE1-CG 3.94Å; F134-L138 HydrophobicContact CZ-CD1 4.12Å; F134-L138 HydrophobicContact CZ-CD2 4.07Å; F134-L138 HydrophobicContact CZ-CG 4.12Å; F134-L138 WeakPolarHBondContact O-CG 2.88Å; F134-L138 PolarHBondContact O-N 2.97Å
135	F	94.8	Very high	95	Very high	10 Å²	10	27.3 Å²	27.3	4%	0.044	14%	0.137	C	C	.	.	H	α-helix	trans	-63.2	-43.8	177.3	-172.9	-103.9	0	0	0	111.8	F131 G132 A137 L138 G139 L312 W467 F501 L508	F131-F135 HydrophobicContact CE1-CB 4.44Å; F131-F135 WeakPolarHBondContact O-CB 3.14Å; F131-F135 PolarHBondContact O-N 3.27Å; G132-F135 PolarHBondContact O-N 3.07Å; F135-A137 VanDerWaalsContact C-N 3.33Å; F135-A137 PolarHBondContact O-N 2.68Å; F135-L138 PolarHBondContact O-N 3.12Å; F135-G139 PolarHBondContact O-N 3.44Å; F135-G139 VanDerWaalsContact O-N 3.09Å; F135-L312 HydrophobicContact CB-CD2 4.4Å; F135-L312 HydrophobicContact CD1-CD1 4.1Å; F135-L312 HydrophobicContact CD1-CD2 3.81Å; F135-L312 HydrophobicContact CE1-CD1 4.37Å; F135-W467 HydrophobicContact CD1-CH2 4.2Å; F135-W467 AromaticContact CE1-CH2 3.69Å; F135-W467 HydrophobicContact CE1-CH2 3.69Å; F135-W467 AromaticContact CE1-CZ3 3.7Å; F135-W467 HydrophobicContact CE1-CZ3 3.7Å; F135-F501 HydrophobicContact CD1-CD2 4.33Å; F135-F501 AromaticContact CD1-CE2 3.87Å; F135-F501 HydrophobicContact CD1-CE2 3.87Å; F135-F501 AromaticContact CD2-CD2 3.93Å; F135-F501 HydrophobicContact CD2-CD2 3.93Å; F135-F501 HydrophobicContact CD2-CE2 4.3Å; F135-F501 AromaticContact CE1-CD2 3.96Å; F135-F501 HydrophobicContact CE1-CD2 3.96Å; F135-F501 AromaticContact CE1-CE2 3.45Å; F135-F501 HydrophobicContact CE1-CE2 3.45Å; F135-F501 VanDerWaalsContact CE1-CE2 3.45Å; F135-F501 HydrophobicContact CE1-CZ 4.35Å; F135-F501 AromaticContact CE2-CD2 3.48Å; F135-F501 HydrophobicContact CE2-CD2 3.48Å; F135-F501 VanDerWaalsContact CE2-CD2 3.48Å; F135-F501 AromaticContact CE2-CE2 3.9Å; F135-F501 HydrophobicContact CE2-CE2 3.9Å; F135-F501 HydrophobicContact CE2-CG 4.42Å; F135-F501 HydrophobicContact CG-CD2 4.33Å; F135-F501 HydrophobicContact CG-CE2 4.28Å; F135-F501 AromaticContact CZ-CD2 3.5Å; F135-F501 HydrophobicContact CZ-CD2 3.5Å; F135-F501 AromaticContact CZ-CE2 3.46Å; F135-F501 HydrophobicContact CZ-CE2 3.46Å; F135-F501 VanDerWaalsContact CZ-CE2 3.46Å; F135-F501 HydrophobicContact CZ-CG 4.47Å; F135-F501 HydrophobicContact CZ-CZ 4.41Å; F135-F501 WeakPolarHBondContact O-CE2 3.4Å; F135-L508 HydrophobicContact CE1-CD1 3.67Å; F135-L508 HydrophobicContact CZ-CD1 4.07Å
136	A	93.3	Very high	95	Very high	3 Å²	3	27.4 Å²	27.4	3%	0.025	14%	0.137	C	C	.	.	H	α-helix	trans	-60.9	-41.6	172.8	0	0	0	0	0	111.8	G132 G133 L138 G139 A140 Y315 W318	G132-A136 WeakPolarHBondContact O-CB 3.33Å; G132-A136 PolarHBondContact O-N 3.12Å; G133-A136 PolarHBondContact O-N 3.29Å; A136-L138 PolarHBondContact O-N 2.84Å; A136-G139 PolarHBondContact O-N 3.35Å; A136-A140 WeakPolarHBondContact O-CB 3.26Å; A136-A140 PolarHBondContact O-N 2.87Å; A136-Y315 HydrophobicContact CB-CD1 4.47Å; A136-Y315 HydrophobicContact CB-CG 4.4Å; A136-W318 HydrophobicContact CB-CG 4.34Å
137	A	95.3	Very high	94.8	Very high	35 Å²	35	26 Å²	26	29%	0.289	13%	0.13	S	C	.	.	H	α-helix	trans	-63.7	-38.6	176.4	0	0	0	0	0	112.6	G133 F134 F135 A140 Y141 C343	G133-A137 WeakPolarHBondContact O-CB 3.41Å; G133-A137 PolarHBondContact O-N 3.5Å; F134-A137 WeakPolarHBondContact O-CB 3.49Å; F134-A137 PolarHBondContact O-N 3.37Å; F135-A137 VanDerWaalsContact C-N 3.33Å; F135-A137 PolarHBondContact O-N 2.68Å; A137-A140 PolarHBondContact O-N 2.85Å; A137-Y141 WeakPolarHBondContact O-CB 3.49Å; A137-Y141 PolarHBondContact O-N 3.49Å; A137-C343 HydrophobicContact CB-CB 3.99Å
138	L	95.4	Very high	94.7	Very high	13 Å²	13	22 Å²	22	7%	0.068	11%	0.11	C	C	.	.	H	α-helix	trans	-61.8	-45.6	173.2	-73	-179.7	0	0	0	111.7	F134 F135 A136 A140 Y141 C142 F497 I500 F501	F134-L138 HydrophobicContact CD1-CD1 4.03Å; F134-L138 HydrophobicContact CD1-CG 4.3Å; F134-L138 HydrophobicContact CE1-CD1 3.55Å; F134-L138 HydrophobicContact CE1-CD2 4.34Å; F134-L138 HydrophobicContact CE1-CG 3.94Å; F134-L138 HydrophobicContact CZ-CD1 4.12Å; F134-L138 HydrophobicContact CZ-CD2 4.07Å; F134-L138 HydrophobicContact CZ-CG 4.12Å; F134-L138 WeakPolarHBondContact O-CG 2.88Å; F134-L138 PolarHBondContact O-N 2.97Å; F135-L138 PolarHBondContact O-N 3.12Å; A136-L138 PolarHBondContact O-N 2.84Å; L138-A140 VanDerWaalsContact C-N 3.35Å; L138-Y141 PolarHBondContact O-N 3.25Å; L138-C142 PolarHBondContact O-N 3.42Å; L138-C142 VanDerWaalsContact O-N 3.07Å; L138-C142 PolarHBondContact O-SG 3.47Å; L138-F497 HydrophobicContact CD2-CB 4.13Å; L138-F497 HydrophobicContact CD2-CD1 3.58Å; L138-F497 HydrophobicContact CD2-CE1 4.35Å; L138-F497 HydrophobicContact CD2-CG 4.17Å; L138-I500 HydrophobicContact CD1-CG2 4.31Å; L138-F501 HydrophobicContact CB-CB 4.38Å; L138-F501 HydrophobicContact CB-CD2 4.17Å
139	G	94.1	Very high	94.6	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-59.1	-47.6	174.8	0	0	0	0	0	111.8	F135 A136 Y141 C142 Y143 W318 F501	F135-G139 PolarHBondContact O-N 3.44Å; F135-G139 VanDerWaalsContact O-N 3.09Å; A136-G139 PolarHBondContact O-N 3.35Å; G139-Y141 VanDerWaalsContact C-N 3.3Å; G139-Y141 PolarHBondContact O-N 2.9Å; G139-C142 WeakPolarHBondContact O-CB 3.24Å; G139-C142 PolarHBondContact O-N 3.43Å; G139-Y143 VanDerWaalsContact O-CD2 3.28Å; G139-Y143 WeakPolarHBondContact O-CD2 2.88Å; G139-Y143 PolarHBondContact O-N 3.21Å; G139-W318 WeakPolarHBondContact O-CZ3 3.29Å; G139-F501 VanDerWaalsContact CA-CE1 3.45Å; G139-F501 VanDerWaalsContact CA-CE2 3.44Å
140	A	94.2	Very high	94.4	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-64.4	-35.7	179.7	0	0	0	0	0	112.1	A136 A137 L138 Y143 S144 W318 I339	A136-A140 WeakPolarHBondContact O-CB 3.26Å; A136-A140 PolarHBondContact O-N 2.87Å; A137-A140 PolarHBondContact O-N 2.85Å; L138-A140 VanDerWaalsContact C-N 3.35Å; A140-Y143 CarbonylContact O-C 3.6Å; A140-Y143 WeakPolarHBondContact O-CB 3.49Å; A140-Y143 PolarHBondContact O-N 3.11Å; A140-S144 PolarHBondContact O-N 2.78Å; A140-W318 VanDerWaalsContact CA-CE3 3.43Å; A140-W318 HydrophobicContact CB-CB 4.31Å; A140-W318 HydrophobicContact CB-CD2 4.32Å; A140-W318 HydrophobicContact CB-CE3 3.61Å; A140-W318 HydrophobicContact CB-CZ3 4.31Å; A140-I339 HydrophobicContact CB-CG2 3.28Å
141	Y	94.8	Very high	94	Very high	91 Å²	91	25 Å²	25	36%	0.357	12%	0.116	S	C	.	.	H	α-helix	trans	-63.1	-44.7	173.6	-175.5	-133.1	0	0	0	111.9	A137 L138 G139 Y143 S144 I491 V493 F497	A137-Y141 WeakPolarHBondContact O-CB 3.49Å; A137-Y141 PolarHBondContact O-N 3.49Å; L138-Y141 PolarHBondContact O-N 3.25Å; G139-Y141 VanDerWaalsContact C-N 3.3Å; G139-Y141 PolarHBondContact O-N 2.9Å; Y141-Y143 VanDerWaalsContact C-N 3.26Å; Y141-Y143 PolarHBondContact O-N 3.23Å; Y141-S144 WeakPolarHBondContact O-CB 3.15Å; Y141-S144 PolarHBondContact O-N 3.42Å; Y141-S144 VanDerWaalsContact O-N 3.14Å; Y141-S144 PolarHBondContact O-OG 3.11Å; Y141-I491 HydrophobicContact CE2-CG2 4.16Å; Y141-V493 HydrophobicContact CD1-CB 4.36Å; Y141-V493 HydrophobicContact CD1-CG1 3.64Å; Y141-V493 HydrophobicContact CD1-CG2 3.95Å; Y141-V493 HydrophobicContact CD2-CG2 4.04Å; Y141-V493 HydrophobicContact CE1-CB 3.94Å; Y141-V493 HydrophobicContact CE1-CG1 3.43Å; Y141-V493 VanDerWaalsContact CE1-CG1 3.43Å; Y141-V493 HydrophobicContact CE1-CG2 3.76Å; Y141-V493 HydrophobicContact CE2-CG2 3.84Å; Y141-V493 HydrophobicContact CG-CG2 4.08Å; Y141-V493 WeakPolarHBondContact O-CG2 3.16Å; Y141-F497 HydrophobicContact CD1-CD2 4.5Å; Y141-F497 HydrophobicContact CE1-CD2 4.04Å
142	C	95.1	Very high	93.6	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-58.2	-41.7	173.3	-59.6	0	0	0	0	111.6	L138 G139 S144 E145 L146 L477 P498	L138-C142 PolarHBondContact O-N 3.42Å; L138-C142 VanDerWaalsContact O-N 3.07Å; L138-C142 PolarHBondContact O-SG 3.47Å; G139-C142 WeakPolarHBondContact O-CB 3.24Å; G139-C142 PolarHBondContact O-N 3.43Å; C142-S144 VanDerWaalsContact C-N 3.3Å; C142-S144 PolarHBondContact O-N 3.49Å; C142-E145 PolarHBondContact O-N 3.31Å; C142-L146 PolarHBondContact O-N 3.15Å; C142-L477 HydrophobicContact CB-CD1 4.12Å; C142-P498 VanDerWaalsContact SG-CA 3.54Å
143	Y	94.4	Very high	93.2	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-70.2	-23.4	179.1	-90.4	-123	0	0	0	114.2	G139 A140 Y141 L146 G147 D156 Y159 W318 N319 N322 A473	G139-Y143 VanDerWaalsContact O-CD2 3.28Å; G139-Y143 WeakPolarHBondContact O-CD2 2.88Å; G139-Y143 PolarHBondContact O-N 3.21Å; A140-Y143 CarbonylContact O-C 3.6Å; A140-Y143 WeakPolarHBondContact O-CB 3.49Å; A140-Y143 PolarHBondContact O-N 3.11Å; Y141-Y143 VanDerWaalsContact C-N 3.26Å; Y141-Y143 PolarHBondContact O-N 3.23Å; Y143-L146 HydrophobicContact CD2-CD1 4.5Å; Y143-L146 PolarHBondContact O-N 3.38Å; Y143-G147 PolarHBondContact O-N 3.01Å; Y143-D156 WeakPolarHBondContact CE1-OD1 3.37Å; Y143-D156 PolarHBondContact OH-OD1 3.35Å; Y143-Y159 AromaticContact CD1-CE2 3.81Å; Y143-Y159 HydrophobicContact CD1-CE2 3.81Å; Y143-Y159 HydrophobicContact CE1-CD2 4.34Å; Y143-Y159 AromaticContact CE1-CE2 3.94Å; Y143-Y159 HydrophobicContact CE1-CE2 3.94Å; Y143-Y159 HydrophobicContact CG-CE2 4.44Å; Y143-W318 HydrophobicContact CD1-CH2 4.45Å; Y143-W318 AromaticContact CD1-CZ3 3.9Å; Y143-W318 HydrophobicContact CD1-CZ3 3.9Å; Y143-W318 AromaticContact CD2-CH2 3.73Å; Y143-W318 HydrophobicContact CD2-CH2 3.73Å; Y143-W318 AromaticContact CD2-CZ3 3.55Å; Y143-W318 HydrophobicContact CD2-CZ3 3.55Å; Y143-W318 HydrophobicContact CE1-CH2 4.31Å; Y143-W318 HydrophobicContact CE1-CZ3 4.18Å; Y143-W318 AromaticContact CE2-CH2 3.57Å; Y143-W318 HydrophobicContact CE2-CH2 3.57Å; Y143-W318 AromaticContact CE2-CZ3 3.87Å; Y143-W318 HydrophobicContact CE2-CZ3 3.87Å; Y143-W318 HydrophobicContact CG-CH2 4.16Å; Y143-W318 AromaticContact CG-CZ3 3.56Å; Y143-W318 HydrophobicContact CG-CZ3 3.56Å; Y143-W318 AromaticContact CZ-CH2 3.87Å; Y143-N319 HydrophobicContact CD1-CB 3.59Å; Y143-N319 HydrophobicContact CE1-CB 3.55Å; Y143-N319 HydrophobicContact CG-CB 4.47Å; Y143-N322 HydrophobicContact CD1-CB 4.41Å; Y143-N322 PolarHBondContact O-ND2 2.95Å; Y143-A473 HydrophobicContact CE2-CB 4.04Å; Y143-A473 WeakPolarHBondContact OH-CB 3.35Å
144	S	94	Very high	92.7	Very high	2 Å²	2	24.7 Å²	24.7	1%	0.014	11%	0.114	C	C	.	.	H	α-helix	trans	-66	-40.5	174.5	78.1	0	0	0	0	111.6	A140 Y141 C142 T148	A140-S144 PolarHBondContact O-N 2.78Å; Y141-S144 WeakPolarHBondContact O-CB 3.15Å; Y141-S144 PolarHBondContact O-N 3.42Å; Y141-S144 VanDerWaalsContact O-N 3.14Å; Y141-S144 PolarHBondContact O-OG 3.11Å; C142-S144 VanDerWaalsContact C-N 3.3Å; C142-S144 PolarHBondContact O-N 3.49Å; S144-T148 WeakPolarHBondContact O-CB 3.17Å; S144-T148 WeakPolarHBondContact O-CG2 3.18Å; S144-T148 PolarHBondContact O-N 3.21Å; S144-T148 PolarHBondContact O-OG1 3.5Å
145	E	94.5	Very high	92.4	Very high	2 Å²	2	19 Å²	19	1%	0.009	9%	0.089	C	C	.	.	H	α-helix	trans	-67.1	-46.3	173.2	172.3	171	170.3	0	0	111	C142 G147 T148 L149 L477 R481 R489 I491 V493	C142-E145 PolarHBondContact O-N 3.31Å; E145-G147 PolarHBondContact O-N 3.32Å; E145-T148 PolarHBondContact O-N 2.92Å; E145-T148 PolarHBondContact O-OG1 3.42Å; E145-T148 VanDerWaalsContact O-OG1 3.11Å; E145-L149 VanDerWaalsContact O-CB 3.29Å; E145-L149 WeakPolarHBondContact O-CB 3.49Å; E145-L149 PolarHBondContact O-N 2.84Å; E145-L477 HydrophobicContact CB-CD1 4.39Å; E145-R481 IonicContact OE1-CZ 3.29Å; E145-R481 IonicContact OE1-NE 3.71Å; E145-R481 PolarHBondContact OE1-NE 3.29Å; E145-R481 IonicContact OE1-NH2 2.74Å; E145-R481 PolarHBondContact OE1-NH2 3.06Å; E145-R481 IonicContact OE2-CZ 3.25Å; E145-R481 IonicContact OE2-NE 2.71Å; E145-R481 IonicContact OE2-NH2 3.64Å; E145-R481 PolarHBondContact OE2-NH2 2.76Å; E145-R489 WeakPolarHBondContact OE1-CD 3.49Å; E145-R489 IonicContact OE1-CZ 3.09Å; E145-R489 IonicContact OE1-NH1 3.75Å; E145-R489 PolarHBondContact OE1-NH1 3.03Å; E145-I491 WeakPolarHBondContact CG-O 3.37Å; E145-V493 HydrophobicContact CB-CG2 3.89Å; E145-V493 VanDerWaalsContact OE2-CB 3.3Å; E145-V493 WeakPolarHBondContact OE2-CB 3.42Å; E145-V493 PolarHBondContact OE2-N 3.22Å
146	L	94.4	Very high	92.2	Very high	2 Å²	2	18.6 Å²	18.6	1%	0.01	9%	0.087	C	C	.	.	H	α-helix	trans	-60.8	-44.4	179.2	-72	171.8	0	0	0	112.1	C142 Y143 L149 I150 Y159 A473 L477 L480	C142-L146 PolarHBondContact O-N 3.15Å; Y143-L146 HydrophobicContact CD2-CD1 4.5Å; Y143-L146 PolarHBondContact O-N 3.38Å; L146-L149 PolarHBondContact O-N 2.81Å; L146-I150 PolarHBondContact O-N 3.18Å; L146-Y159 HydrophobicContact CB-CD1 4Å; L146-Y159 HydrophobicContact CB-CD2 3.85Å; L146-Y159 HydrophobicContact CB-CE1 3.92Å; L146-Y159 HydrophobicContact CB-CE2 3.75Å; L146-Y159 HydrophobicContact CB-CG 3.97Å; L146-Y159 HydrophobicContact CD1-CD2 3.82Å; L146-Y159 HydrophobicContact CD1-CE2 4.3Å; L146-Y159 HydrophobicContact CD1-CG 4.2Å; L146-Y159 HydrophobicContact CG-CD2 4.39Å; L146-Y159 HydrophobicContact CG-CG 4.47Å; L146-Y159 WeakPolarHBondContact O-CE1 3.36Å; L146-A473 WeakPolarHBondContact CD1-O 3.49Å; L146-L477 HydrophobicContact CD1-CB 4.34Å; L146-L477 HydrophobicContact CD2-CB 4.01Å; L146-L477 HydrophobicContact CG-CB 4.23Å; L146-L477 HydrophobicContact CG-CD1 4.4Å; L146-L480 HydrophobicContact CD2-CD1 3.87Å
147	G	92.7	Very high	92.1	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-76.7	-24.5	-178.8	0	0	0	0	0	114.6	Y143 E145 Y159	Y143-G147 PolarHBondContact O-N 3.01Å; E145-G147 PolarHBondContact O-N 3.32Å; G147-Y159 WeakPolarHBondContact CA-OH 3.36Å; G147-Y159 PolarHBondContact N-OH 2.94Å
148	T	92.6	Very high	91.9	Very high	6 Å²	6	17.1 Å²	17.1	4%	0.037	7%	0.074	C	C	.	.	H	α-helix	trans	-78.6	-27.8	171	53.7	0	0	0	0	112.3	S144 E145 L335 P336	S144-T148 WeakPolarHBondContact O-CB 3.17Å; S144-T148 WeakPolarHBondContact O-CG2 3.18Å; S144-T148 PolarHBondContact O-N 3.21Å; S144-T148 PolarHBondContact O-OG1 3.5Å; E145-T148 PolarHBondContact O-N 2.92Å; E145-T148 PolarHBondContact O-OG1 3.42Å; E145-T148 VanDerWaalsContact O-OG1 3.11Å; T148-L335 HydrophobicContact CG2-CD2 4.42Å; T148-P336 HydrophobicContact CG2-CG 3.86Å
149	L	92.5	Very high	91.8	Very high	32 Å²	32	16.5 Å²	16.5	17%	0.168	7%	0.071	C	C	.	.	H	α-helix	trans	-77.8	-57.5	173.2	-178.5	64.5	0	0	0	111.7	E145 L146 L480 A487 R489	E145-L149 VanDerWaalsContact O-CB 3.29Å; E145-L149 WeakPolarHBondContact O-CB 3.49Å; E145-L149 PolarHBondContact O-N 2.84Å; L146-L149 PolarHBondContact O-N 2.81Å; L149-L480 HydrophobicContact CD2-CB 4.34Å; L149-L480 HydrophobicContact CD2-CD1 4.39Å; L149-A487 HydrophobicContact CD1-CB 3.7Å; L149-R489 HydrophobicContact CD1-CG 4.47Å
150	I	92	Very high	91.8	Very high	15 Å²	15	16.6 Å²	16.6	8%	0.077	7%	0.072	C	C	.	.			trans	-100.4	90.8	-178.4	-57.9	169.7	0	0	0	108.5	L146 K152 A158 Y159 T162 L480	L146-I150 PolarHBondContact O-N 3.18Å; I150-K152 HydrophobicContact CG2-CB 4.16Å; I150-K152 HydrophobicContact CG2-CG 4.43Å; I150-K152 PolarHBondContact O-N 3.49Å; I150-K152 VanDerWaalsContact O-N 3.07Å; I150-A158 HydrophobicContact CG2-CB 4.21Å; I150-Y159 HydrophobicContact CB-CD1 3.89Å; I150-Y159 HydrophobicContact CB-CE1 3.98Å; I150-Y159 HydrophobicContact CD1-CD1 3.91Å; I150-Y159 HydrophobicContact CG1-CD1 4.45Å; I150-Y159 HydrophobicContact CG2-CD1 4.19Å; I150-Y159 HydrophobicContact CG2-CE1 4.39Å; I150-T162 HydrophobicContact CD1-CG2 3.79Å; I150-T162 HydrophobicContact CG1-CG2 4.45Å; I150-L480 HydrophobicContact CD1-CD1 3.59Å
151	R	88.9	Confident	91.7	Very high	100 Å²	100	17.5 Å²	17.5	38%	0.377	8%	0.077	S	C	.	.			trans	-84.6	37.1	-179	-62	174	-72.7	166.7	0.1	112.7	E326	R151-E326 WeakPolarHBondContact O-CG 3.49Å
152	K	87.3	Confident	91.5	Very high	87 Å²	87	15.9 Å²	15.9	38%	0.378	8%	0.077	S	C	.	.			trans	-98.5	143.5	174.7	-73	-174.7	173.6	-173.9	0	109.5	I150 A158 V325 E326 E417	I150-K152 HydrophobicContact CG2-CB 4.16Å; I150-K152 HydrophobicContact CG2-CG 4.43Å; I150-K152 PolarHBondContact O-N 3.49Å; I150-K152 VanDerWaalsContact O-N 3.07Å; K152-A158 HydrophobicContact CB-CB 4.18Å; K152-V325 VanDerWaalsContact O-CG1 3.32Å; K152-V325 WeakPolarHBondContact O-CG1 3.42Å; K152-E326 WeakPolarHBondContact CA-OE1 3.2Å; K152-E417 IonicContact NZ-OE1 2.95Å; K152-E417 PolarHBondContact NZ-OE1 3.27Å
153	S	85.1	Confident	91.4	Very high	2 Å²	2	17 Å²	17	1%	0.014	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.5	154.8	170.7	-70.5	0	0	0	0	110.8	F323 E326 A413	S153-F323 WeakPolarHBondContact CA-O 3.47Å; S153-F323 WeakPolarHBondContact CB-O 3.4Å; S153-E326 PolarHBondContact N-OE1 2.81Å; S153-E326 WeakPolarHBondContact OG-CB 3.46Å; S153-E326 WeakPolarHBondContact OG-CG 3.42Å; S153-A413 WeakPolarHBondContact O-CB 3.29Å
154	G	85.1	Confident	91.3	Very high	0 Å²	0	19.8 Å²	19.8	0%	0	10%	0.099	C	C	.	.	T	Hydrogen-bonded Turn	trans	107.9	-3.9	179.2	0	0	0	0	0	116.1	D156 Y157 F323	G154-D156 PolarHBondContact O-N 3.38Å; G154-Y157 WeakPolarHBondContact O-CB 3.32Å; G154-Y157 PolarHBondContact O-N 2.95Å; G154-F323 PolarHBondContact N-O 3.47Å; G154-F323 WeakPolarHBondContact O-CD1 3.31Å; G154-F323 WeakPolarHBondContact O-CE1 3.47Å
155	G	89.9	Confident	91.1	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	11%	0.108	C	C	.	.	T	Hydrogen-bonded Turn	trans	56	-124.8	169.3	0	0	0	0	0	113	Y157 A158 Y159 N322	G155-Y157 PolarHBondContact O-N 3.26Å; G155-Y157 VanDerWaalsContact O-N 3.11Å; G155-A158 WeakPolarHBondContact O-CB 3.32Å; G155-A158 PolarHBondContact O-N 3.41Å; G155-Y159 WeakPolarHBondContact O-CD2 3.33Å; G155-Y159 PolarHBondContact O-N 2.9Å; G155-Y159 VanDerWaalsContact O-N 3.16Å; G155-N322 PolarHBondContact N-O 3.32Å
156	D	90	Very high	90.7	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-45.3	-45.2	178.6	-51	-8.2	0	0	0	112.5	Y143 G154 A158 Y159 I160 R172 N319 F323 A473	Y143-D156 WeakPolarHBondContact CE1-OD1 3.37Å; Y143-D156 PolarHBondContact OH-OD1 3.35Å; G154-D156 PolarHBondContact O-N 3.38Å; D156-A158 VanDerWaalsContact C-N 3.32Å; D156-A158 PolarHBondContact O-N 3.38Å; D156-Y159 PolarHBondContact O-N 3.08Å; D156-I160 HydrophobicContact CB-CD1 4.33Å; D156-I160 WeakPolarHBondContact O-CB 3.28Å; D156-I160 WeakPolarHBondContact O-CG1 3.2Å; D156-I160 PolarHBondContact O-N 3.12Å; D156-R172 HydrophobicContact CB-CG 4.34Å; D156-R172 VanDerWaalsContact CB-NE 3.32Å; D156-R172 IonicContact OD2-CZ 2.74Å; D156-R172 VanDerWaalsContact OD2-CZ 3.29Å; D156-R172 IonicContact OD2-NE 3.27Å; D156-R172 PolarHBondContact OD2-NE 2.86Å; D156-R172 VanDerWaalsContact OD2-NE 3.09Å; D156-R172 IonicContact OD2-NH2 3.4Å; D156-R172 PolarHBondContact OD2-NH2 3.22Å; D156-N319 PolarHBondContact OD1-ND2 3.43Å; D156-F323 HydrophobicContact CB-CZ 4.49Å; D156-A473 HydrophobicContact CB-CB 4.32Å
157	Y	90.6	Very high	90.5	Very high	3 Å²	3	27.3 Å²	27.3	1%	0.012	14%	0.143	C	C	.	.	H	α-helix	trans	-60	-43.7	-178.4	164.7	-98.7	0	0	0	111.3	G154 G155 T161 G169 L173 L410 A413 E417 H419	G154-Y157 WeakPolarHBondContact O-CB 3.32Å; G154-Y157 PolarHBondContact O-N 2.95Å; G155-Y157 PolarHBondContact O-N 3.26Å; G155-Y157 VanDerWaalsContact O-N 3.11Å; Y157-T161 WeakPolarHBondContact CE2-OG1 3.35Å; Y157-T161 WeakPolarHBondContact O-CB 3.23Å; Y157-T161 PolarHBondContact O-N 2.86Å; Y157-T161 PolarHBondContact O-OG1 3.4Å; Y157-G169 WeakPolarHBondContact CD2-O 3.49Å; Y157-G169 WeakPolarHBondContact CE2-O 3.33Å; Y157-L173 HydrophobicContact CD2-CB 3.82Å; Y157-L173 HydrophobicContact CD2-CD1 4.41Å; Y157-L173 HydrophobicContact CD2-CG 4.49Å; Y157-L173 HydrophobicContact CE2-CB 3.96Å; Y157-L173 HydrophobicContact CE2-CD2 4.04Å; Y157-L173 HydrophobicContact CE2-CG 4.46Å; Y157-L410 HydrophobicContact CD1-CD1 4.12Å; Y157-L410 HydrophobicContact CG-CD1 3.81Å; Y157-A413 HydrophobicContact CD1-CB 4.37Å; Y157-A413 HydrophobicContact CE1-CB 4.36Å; Y157-E417 HydrophobicContact CE1-CG 4.2Å; Y157-E417 WeakPolarHBondContact OH-CB 3.44Å; Y157-E417 WeakPolarHBondContact OH-CG 3.36Å; Y157-H419 AromaticContact CE2-ND1 3.56Å; Y157-H419 AromaticContact CZ-ND1 3.57Å; Y157-H419 PolarHBondContact OH-CE1 2.95Å; Y157-H419 PolarHBondContact OH-ND1 2.74Å
158	A	91.2	Very high	90.3	Very high	5 Å²	5	29.4 Å²	29.4	4%	0.041	15%	0.154	C	C	.	.	H	α-helix	trans	-66.7	-39.6	179	0	0	0	0	0	111.3	I150 K152 G155 D156 T162	I150-A158 HydrophobicContact CG2-CB 4.21Å; K152-A158 HydrophobicContact CB-CB 4.18Å; G155-A158 WeakPolarHBondContact O-CB 3.32Å; G155-A158 PolarHBondContact O-N 3.41Å; D156-A158 VanDerWaalsContact C-N 3.32Å; D156-A158 PolarHBondContact O-N 3.38Å; A158-T162 WeakPolarHBondContact O-CB 3.35Å; A158-T162 PolarHBondContact O-N 2.91Å; A158-T162 VanDerWaalsContact O-N 3.07Å; A158-T162 PolarHBondContact O-OG1 3.37Å
159	Y	94.3	Very high	90	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-68.1	-48.9	179.6	-50.4	-30.6	0	0	0	111.8	Y143 L146 G147 I150 G155 D156 T162 A163 N322	Y143-Y159 AromaticContact CD1-CE2 3.81Å; Y143-Y159 HydrophobicContact CD1-CE2 3.81Å; Y143-Y159 HydrophobicContact CE1-CD2 4.34Å; Y143-Y159 AromaticContact CE1-CE2 3.94Å; Y143-Y159 HydrophobicContact CE1-CE2 3.94Å; Y143-Y159 HydrophobicContact CG-CE2 4.44Å; L146-Y159 HydrophobicContact CB-CD1 4Å; L146-Y159 HydrophobicContact CB-CD2 3.85Å; L146-Y159 HydrophobicContact CB-CE1 3.92Å; L146-Y159 HydrophobicContact CB-CE2 3.75Å; L146-Y159 HydrophobicContact CB-CG 3.97Å; L146-Y159 HydrophobicContact CD1-CD2 3.82Å; L146-Y159 HydrophobicContact CD1-CE2 4.3Å; L146-Y159 HydrophobicContact CD1-CG 4.2Å; L146-Y159 HydrophobicContact CG-CD2 4.39Å; L146-Y159 HydrophobicContact CG-CG 4.47Å; L146-Y159 WeakPolarHBondContact O-CE1 3.36Å; G147-Y159 WeakPolarHBondContact CA-OH 3.36Å; G147-Y159 PolarHBondContact N-OH 2.94Å; I150-Y159 HydrophobicContact CB-CD1 3.89Å; I150-Y159 HydrophobicContact CB-CE1 3.98Å; I150-Y159 HydrophobicContact CD1-CD1 3.91Å; I150-Y159 HydrophobicContact CG1-CD1 4.45Å; I150-Y159 HydrophobicContact CG2-CD1 4.19Å; I150-Y159 HydrophobicContact CG2-CE1 4.39Å; G155-Y159 WeakPolarHBondContact O-CD2 3.33Å; G155-Y159 PolarHBondContact O-N 2.9Å; G155-Y159 VanDerWaalsContact O-N 3.16Å; D156-Y159 PolarHBondContact O-N 3.08Å; Y159-T162 PolarHBondContact O-N 3.2Å; Y159-A163 WeakPolarHBondContact O-CB 3.31Å; Y159-A163 PolarHBondContact O-N 3.32Å; Y159-N322 WeakPolarHBondContact OH-CB 3.5Å; Y159-N322 PolarHBondContact OH-ND2 3.14Å
160	I	93.7	Very high	89.7	Confident	2 Å²	2	27.8 Å²	27.8	1%	0.01	15%	0.145	C	C	.	.	H	α-helix	trans	-64	-44.9	179.7	-67.5	168.8	0	0	0	110.3	D156 T162 A163 F164 I168 R172 F472 A473	D156-I160 HydrophobicContact CB-CD1 4.33Å; D156-I160 WeakPolarHBondContact O-CB 3.28Å; D156-I160 WeakPolarHBondContact O-CG1 3.2Å; D156-I160 PolarHBondContact O-N 3.12Å; I160-T162 VanDerWaalsContact C-N 3.28Å; I160-T162 PolarHBondContact O-N 2.93Å; I160-A163 PolarHBondContact O-N 3Å; I160-F164 HydrophobicContact CG2-CD2 4.25Å; I160-F164 WeakPolarHBondContact O-CB 3.47Å; I160-F164 PolarHBondContact O-N 2.93Å; I160-I168 HydrophobicContact CG2-CB 3.93Å; I160-I168 HydrophobicContact CG2-CG2 3.51Å; I160-R172 HydrophobicContact CD1-CB 4.1Å; I160-R172 HydrophobicContact CD1-CG 3.93Å; I160-F472 HydrophobicContact CD1-CB 3.94Å; I160-F472 HydrophobicContact CG1-CB 4.16Å; I160-A473 HydrophobicContact CD1-CB 4.29Å; I160-A473 HydrophobicContact CG1-CB 4.27Å
161	T	91.7	Very high	89.4	Confident	18 Å²	18	28.2 Å²	28.2	11%	0.11	15%	0.148	C	C	.	.	H	α-helix	trans	-61.2	-39	177.7	-57.8	0	0	0	0	111.5	Y157 G165 G169	Y157-T161 WeakPolarHBondContact CE2-OG1 3.35Å; Y157-T161 WeakPolarHBondContact O-CB 3.23Å; Y157-T161 PolarHBondContact O-N 2.86Å; Y157-T161 PolarHBondContact O-OG1 3.4Å; T161-G165 CarbonylContact O-C 3.13Å; T161-G165 WeakPolarHBondContact O-CA 3.28Å; T161-G165 PolarHBondContact O-N 3.19Å; T161-G169 VanDerWaalsContact OG1-CA 3.28Å; T161-G169 WeakPolarHBondContact OG1-CA 3.07Å
162	T	91.2	Very high	89.2	Confident	57 Å²	57	23.9 Å²	23.9	35%	0.35	13%	0.131	S	C	.	.	H	α-helix	trans	-72.2	-37.2	179.9	-54.9	0	0	0	0	112.2	I150 A158 Y159 I160 L480 M484	I150-T162 HydrophobicContact CD1-CG2 3.79Å; I150-T162 HydrophobicContact CG1-CG2 4.45Å; A158-T162 WeakPolarHBondContact O-CB 3.35Å; A158-T162 PolarHBondContact O-N 2.91Å; A158-T162 VanDerWaalsContact O-N 3.07Å; A158-T162 PolarHBondContact O-OG1 3.37Å; Y159-T162 PolarHBondContact O-N 3.2Å; I160-T162 VanDerWaalsContact C-N 3.28Å; I160-T162 PolarHBondContact O-N 2.93Å; T162-L480 HydrophobicContact CG2-CD2 4.12Å; T162-M484 HydrophobicContact CG2-CE 4.23Å
163	A	92.7	Very high	89	Confident	25 Å²	25	19.7 Å²	19.7	21%	0.207	11%	0.113	C	C	.	.	H	α-helix	trans	-86.9	-41.5	-175.8	0	0	0	0	0	114	Y159 I160 S476 L479 L480	Y159-A163 WeakPolarHBondContact O-CB 3.31Å; Y159-A163 PolarHBondContact O-N 3.32Å; I160-A163 PolarHBondContact O-N 3Å; A163-S476 VanDerWaalsContact CB-CB 3.44Å; A163-L479 HydrophobicContact CB-CB 4.4Å; A163-L480 HydrophobicContact CB-CD1 4.34Å; A163-L480 HydrophobicContact CB-CD2 4.28Å; A163-L480 HydrophobicContact CB-CG 4.03Å
164	F	92.8	Very high	88.6	Confident	58 Å²	58	21 Å²	21	25%	0.254	12%	0.117	S	C	.	.	H	α-helix	trans	-107.6	-11.2	-174.5	-66.9	-85	0	0	0	113.7	I160 I168 F472 M475 S476 L479	I160-F164 HydrophobicContact CG2-CD2 4.25Å; I160-F164 WeakPolarHBondContact O-CB 3.47Å; I160-F164 PolarHBondContact O-N 2.93Å; F164-I168 HydrophobicContact CB-CB 3.91Å; F164-I168 HydrophobicContact CB-CD1 3.72Å; F164-I168 HydrophobicContact CB-CG1 3.98Å; F164-I168 HydrophobicContact CB-CG2 4.44Å; F164-I168 HydrophobicContact CD1-CD1 3.85Å; F164-I168 HydrophobicContact CG-CD1 3.97Å; F164-F472 HydrophobicContact CD2-CD1 4.46Å; F164-F472 HydrophobicContact CE1-CD1 4.25Å; F164-F472 HydrophobicContact CE1-CE1 4.43Å; F164-F472 HydrophobicContact CE2-CD1 4.05Å; F164-F472 WeakPolarHBondContact CE2-O 3.35Å; F164-F472 AromaticContact CZ-CD1 3.94Å; F164-F472 HydrophobicContact CZ-CD1 3.94Å; F164-M475 HydrophobicContact CE1-CE 4.35Å; F164-M475 HydrophobicContact CE2-CB 4.34Å; F164-M475 HydrophobicContact CZ-CB 3.91Å; F164-M475 HydrophobicContact CZ-CE 3.99Å; F164-S476 VanDerWaalsContact CE2-OG 3.29Å; F164-S476 WeakPolarHBondContact CE2-OG 3.21Å; F164-L479 HydrophobicContact CD1-CD1 3.85Å; F164-L479 HydrophobicContact CD2-CD1 4.38Å; F164-L479 HydrophobicContact CE1-CD1 3.32Å; F164-L479 HydrophobicContact CE2-CD1 3.9Å; F164-L479 HydrophobicContact CG-CD1 4.35Å; F164-L479 HydrophobicContact CZ-CD1 3.34Å; F164-L479 HydrophobicContact CZ-CG 4.39Å
165	G	88.9	Confident	88	Confident	20 Å²	20	21.7 Å²	21.7	21%	0.206	12%	0.121	C	C	.	.			trans	92.4	-178.9	-178.5	0	0	0	0	0	114.1	T161 F167 G169	T161-G165 CarbonylContact O-C 3.13Å; T161-G165 WeakPolarHBondContact O-CA 3.28Å; T161-G165 PolarHBondContact O-N 3.19Å; G165-F167 VanDerWaalsContact C-N 3.34Å; G165-F167 PolarHBondContact O-N 3.3Å; G165-G169 PolarHBondContact O-N 3.36Å
166	P	87.7	Confident	86.9	Confident	66 Å²	66	23.4 Å²	23.4	43%	0.429	13%	0.129	S	C	.	.	H	α-helix	trans	-67.3	-30.2	-166.5	23.9	-33.9	0	0	0	114.3	F170 H419	P166-F170 WeakPolarHBondContact O-CB 3.12Å; P166-F170 PolarHBondContact O-N 2.82Å; P166-H419 WeakPolarHBondContact CB-NE2 3.43Å; P166-H419 PolarHBondContact O-CE1 3.25Å
167	F	89.2	Confident	85.6	Confident	77 Å²	77	23.5 Å²	23.5	34%	0.338	13%	0.13	S	C	.	.	H	α-helix	trans	-64.5	-55.4	-178.4	176.3	-115.9	0	0	0	112.1	G165 G169 F170 I171 I531 Y534	G165-F167 VanDerWaalsContact C-N 3.34Å; G165-F167 PolarHBondContact O-N 3.3Å; F167-G169 VanDerWaalsContact C-N 3.28Å; F167-G169 PolarHBondContact O-N 2.94Å; F167-F170 WeakPolarHBondContact O-CB 3.38Å; F167-F170 PolarHBondContact O-N 3.24Å; F167-F170 VanDerWaalsContact O-N 3.11Å; F167-I171 HydrophobicContact CD1-CD1 4.28Å; F167-I171 HydrophobicContact CE1-CD1 3.77Å; F167-I171 HydrophobicContact CE2-CD1 4.32Å; F167-I171 HydrophobicContact CZ-CD1 3.81Å; F167-I171 HydrophobicContact CZ-CG1 4.48Å; F167-I171 WeakPolarHBondContact O-CG1 3.3Å; F167-I171 PolarHBondContact O-N 3.27Å; F167-I531 HydrophobicContact CE2-CG1 4.44Å; F167-I531 HydrophobicContact CZ-CG1 4.07Å; F167-Y534 HydrophobicContact CB-CE1 4.15Å; F167-Y534 AromaticContact CD2-CD1 3.46Å; F167-Y534 HydrophobicContact CD2-CD1 3.46Å; F167-Y534 VanDerWaalsContact CD2-CD1 3.46Å; F167-Y534 HydrophobicContact CD2-CD2 4.28Å; F167-Y534 AromaticContact CD2-CE1 3.67Å; F167-Y534 HydrophobicContact CD2-CE1 3.67Å; F167-Y534 HydrophobicContact CD2-CE2 4.45Å; F167-Y534 AromaticContact CD2-CG 3.77Å; F167-Y534 HydrophobicContact CD2-CG 3.77Å; F167-Y534 HydrophobicContact CE2-CD1 4.01Å; F167-Y534 HydrophobicContact CE2-CG 4.24Å; F167-Y534 HydrophobicContact CG-CE1 4.36Å
168	I	88.2	Confident	84.2	Confident	44 Å²	44	24.1 Å²	24.1	23%	0.226	13%	0.133	C	C	.	.	H	α-helix	trans	-67.2	-35.2	180	-49.9	-162.2	0	0	0	110.5	I160 F164 F170 I171 R172 F472	I160-I168 HydrophobicContact CG2-CB 3.93Å; I160-I168 HydrophobicContact CG2-CG2 3.51Å; F164-I168 HydrophobicContact CB-CB 3.91Å; F164-I168 HydrophobicContact CB-CD1 3.72Å; F164-I168 HydrophobicContact CB-CG1 3.98Å; F164-I168 HydrophobicContact CB-CG2 4.44Å; F164-I168 HydrophobicContact CD1-CD1 3.85Å; F164-I168 HydrophobicContact CG-CD1 3.97Å; I168-F170 VanDerWaalsContact C-N 3.33Å; I168-F170 PolarHBondContact O-N 3.2Å; I168-I171 PolarHBondContact O-N 3.41Å; I168-R172 PolarHBondContact O-N 2.93Å; I168-F472 HydrophobicContact CD1-CE1 4.3Å; I168-F472 HydrophobicContact CG2-CD1 4.17Å; I168-F472 HydrophobicContact CG2-CE1 4.43Å
169	G	86.4	Confident	82.4	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-55.9	-46.4	169.9	0	0	0	0	0	112.5	Y157 T161 G165 F167 R172 L173	Y157-G169 WeakPolarHBondContact CD2-O 3.49Å; Y157-G169 WeakPolarHBondContact CE2-O 3.33Å; T161-G169 VanDerWaalsContact OG1-CA 3.28Å; T161-G169 WeakPolarHBondContact OG1-CA 3.07Å; G165-G169 PolarHBondContact O-N 3.36Å; F167-G169 VanDerWaalsContact C-N 3.28Å; F167-G169 PolarHBondContact O-N 2.94Å; G169-R172 WeakPolarHBondContact O-CB 3.47Å; G169-R172 PolarHBondContact O-N 3.11Å; G169-L173 PolarHBondContact O-N 3.06Å
170	F	86.6	Confident	80.3	Confident	4 Å²	4	24.9 Å²	24.9	2%	0.018	14%	0.136	C	C	.	.	H	α-helix	trans	-63.4	-42.1	175.9	178.8	-102.2	0	0	0	112.4	P166 F167 I168 R172 L173 W174 H419 S530 V533 Y534 I538	P166-F170 WeakPolarHBondContact O-CB 3.12Å; P166-F170 PolarHBondContact O-N 2.82Å; F167-F170 WeakPolarHBondContact O-CB 3.38Å; F167-F170 PolarHBondContact O-N 3.24Å; F167-F170 VanDerWaalsContact O-N 3.11Å; I168-F170 VanDerWaalsContact C-N 3.33Å; I168-F170 PolarHBondContact O-N 3.2Å; F170-R172 VanDerWaalsContact C-N 3.28Å; F170-R172 PolarHBondContact O-N 3.18Å; F170-L173 CarbonylContact O-C 3.46Å; F170-L173 WeakPolarHBondContact O-CB 3.38Å; F170-L173 PolarHBondContact O-N 2.98Å; F170-L173 VanDerWaalsContact O-N 3.08Å; F170-W174 HydrophobicContact CD1-CB 4.46Å; F170-W174 HydrophobicContact CE1-CB 4.21Å; F170-W174 HydrophobicContact CE1-CD2 4.16Å; F170-W174 AromaticContact CE1-CE3 3.82Å; F170-W174 HydrophobicContact CE1-CE3 3.82Å; F170-W174 HydrophobicContact CE1-CG 4.39Å; F170-W174 HydrophobicContact CE2-CE3 4.06Å; F170-W174 HydrophobicContact CZ-CB 4.46Å; F170-W174 HydrophobicContact CZ-CD2 4.08Å; F170-W174 AromaticContact CZ-CE3 3.29Å; F170-W174 HydrophobicContact CZ-CE3 3.29Å; F170-W174 AromaticContact CZ-CZ3 3.84Å; F170-W174 HydrophobicContact CZ-CZ3 3.84Å; F170-W174 VanDerWaalsContact O-CB 3.26Å; F170-W174 WeakPolarHBondContact O-CB 3.33Å; F170-W174 PolarHBondContact O-N 3.09Å; F170-H419 HydrophobicContact CD2-CB 3.97Å; F170-H419 WeakPolarHBondContact CE2-O 3.22Å; F170-S530 WeakPolarHBondContact CE1-O 3.43Å; F170-V533 HydrophobicContact CZ-CG1 4.26Å; F170-Y534 HydrophobicContact CB-CD2 3.58Å; F170-Y534 HydrophobicContact CB-CE2 3.82Å; F170-Y534 AromaticContact CD1-CD2 3.48Å; F170-Y534 HydrophobicContact CD1-CD2 3.48Å; F170-Y534 VanDerWaalsContact CD1-CD2 3.48Å; F170-Y534 HydrophobicContact CD1-CG 4.01Å; F170-Y534 HydrophobicContact CD2-CD2 4.33Å; F170-Y534 HydrophobicContact CE1-CD2 4.2Å; F170-Y534 HydrophobicContact CE1-CG 4.5Å; F170-Y534 AromaticContact CG-CD2 3.52Å; F170-Y534 HydrophobicContact CG-CD2 3.52Å; F170-Y534 HydrophobicContact CG-CE2 4.22Å; F170-Y534 HydrophobicContact CG-CG 4.47Å; F170-I538 HydrophobicContact CD1-CD1 4.34Å; F170-I538 HydrophobicContact CD2-CD1 3.2Å; F170-I538 HydrophobicContact CE1-CD1 4.33Å; F170-I538 HydrophobicContact CE2-CD1 3.21Å; F170-I538 HydrophobicContact CG-CD1 3.79Å; F170-I538 HydrophobicContact CZ-CD1 3.78Å
171	I	85.8	Confident	78.2	Confident	25 Å²	25	26.4 Å²	26.4	13%	0.128	15%	0.149	C	C	.	.	H	α-helix	trans	-55.1	-47.6	175.2	-60.8	179	0	0	0	109.9	F167 I168 L173 W174 I175 M527 S530	F167-I171 HydrophobicContact CD1-CD1 4.28Å; F167-I171 HydrophobicContact CE1-CD1 3.77Å; F167-I171 HydrophobicContact CE2-CD1 4.32Å; F167-I171 HydrophobicContact CZ-CD1 3.81Å; F167-I171 HydrophobicContact CZ-CG1 4.48Å; F167-I171 WeakPolarHBondContact O-CG1 3.3Å; F167-I171 PolarHBondContact O-N 3.27Å; I168-I171 PolarHBondContact O-N 3.41Å; I171-L173 VanDerWaalsContact C-N 3.31Å; I171-L173 PolarHBondContact O-N 3.16Å; I171-W174 WeakPolarHBondContact O-CB 3.4Å; I171-W174 PolarHBondContact O-N 2.98Å; I171-I175 HydrophobicContact CG2-CD1 3.84Å; I171-I175 HydrophobicContact CG2-CG1 4.38Å; I171-I175 WeakPolarHBondContact O-CD1 3.29Å; I171-I175 WeakPolarHBondContact O-CG1 3.32Å; I171-I175 PolarHBondContact O-N 3.18Å; I171-M527 HydrophobicContact CG2-CG 3.69Å; I171-M527 HydrophobicContact CG2-SD 4.26Å; I171-S530 WeakPolarHBondContact CG1-OG 3.48Å
172	R	84.8	Confident	76.3	Confident	8 Å²	8	28.3 Å²	28.3	3%	0.03	16%	0.158	C	C	.	.	H	α-helix	trans	-57.8	-41.6	176.4	173	65	-175.9	77.3	-10.1	112.7	D156 I160 I168 G169 F170 E176	D156-R172 HydrophobicContact CB-CG 4.34Å; D156-R172 VanDerWaalsContact CB-NE 3.32Å; D156-R172 IonicContact OD2-CZ 2.74Å; D156-R172 VanDerWaalsContact OD2-CZ 3.29Å; D156-R172 IonicContact OD2-NE 3.27Å; D156-R172 PolarHBondContact OD2-NE 2.86Å; D156-R172 VanDerWaalsContact OD2-NE 3.09Å; D156-R172 IonicContact OD2-NH2 3.4Å; D156-R172 PolarHBondContact OD2-NH2 3.22Å; I160-R172 HydrophobicContact CD1-CB 4.1Å; I160-R172 HydrophobicContact CD1-CG 3.93Å; I168-R172 PolarHBondContact O-N 2.93Å; G169-R172 WeakPolarHBondContact O-CB 3.47Å; G169-R172 PolarHBondContact O-N 3.11Å; F170-R172 VanDerWaalsContact C-N 3.28Å; F170-R172 PolarHBondContact O-N 3.18Å; R172-E176 IonicContact CZ-OE1 3.94Å; R172-E176 VanDerWaalsContact NH1-CD 3.25Å; R172-E176 IonicContact NH1-OE1 2.66Å; R172-E176 PolarHBondContact NH1-OE1 2.79Å; R172-E176 IonicContact NH2-OE1 3.7Å; R172-E176 PolarHBondContact NH2-OE1 2.87Å
173	L	82.2	Confident	74.3	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-71.1	-37.5	178.5	-172	66.3	0	0	0	111.8	Y157 G169 F170 I171 E176 A177 L410 F411 H419 M420	Y157-L173 HydrophobicContact CD2-CB 3.82Å; Y157-L173 HydrophobicContact CD2-CD1 4.41Å; Y157-L173 HydrophobicContact CD2-CG 4.49Å; Y157-L173 HydrophobicContact CE2-CB 3.96Å; Y157-L173 HydrophobicContact CE2-CD2 4.04Å; Y157-L173 HydrophobicContact CE2-CG 4.46Å; G169-L173 PolarHBondContact O-N 3.06Å; F170-L173 CarbonylContact O-C 3.46Å; F170-L173 WeakPolarHBondContact O-CB 3.38Å; F170-L173 PolarHBondContact O-N 2.98Å; F170-L173 VanDerWaalsContact O-N 3.08Å; I171-L173 VanDerWaalsContact C-N 3.31Å; I171-L173 PolarHBondContact O-N 3.16Å; L173-E176 PolarHBondContact O-N 2.97Å; L173-A177 WeakPolarHBondContact O-CB 3.33Å; L173-A177 PolarHBondContact O-N 3.49Å; L173-A177 VanDerWaalsContact O-N 3.12Å; L173-L410 HydrophobicContact CD1-CD1 3.7Å; L173-L410 HydrophobicContact CD1-CD2 4Å; L173-L410 HydrophobicContact CD1-CG 3.61Å; L173-F411 HydrophobicContact CD1-CD1 4.2Å; L173-F411 HydrophobicContact CD1-CE1 4.4Å; L173-H419 HydrophobicContact CD2-CB 3.78Å; L173-M420 HydrophobicContact CD2-CE 3.79Å; L173-M420 HydrophobicContact CD2-CG 3.44Å; L173-M420 VanDerWaalsContact CD2-CG 3.44Å; L173-M420 HydrophobicContact CD2-SD 4.35Å; L173-M420 HydrophobicContact CG-CE 3.67Å; L173-M420 HydrophobicContact CG-CG 4.27Å
174	W	78.5	Confident	72.1	Confident	28 Å²	28	27.2 Å²	27.2	11%	0.106	16%	0.156	C	C	.	.	H	α-helix	trans	-67.6	-43.3	179.9	-175.1	-92.8	0	0	0	112.6	F170 I171 E176 A177 I178 T529 S530 V533	F170-W174 HydrophobicContact CD1-CB 4.46Å; F170-W174 HydrophobicContact CE1-CB 4.21Å; F170-W174 HydrophobicContact CE1-CD2 4.16Å; F170-W174 AromaticContact CE1-CE3 3.82Å; F170-W174 HydrophobicContact CE1-CE3 3.82Å; F170-W174 HydrophobicContact CE1-CG 4.39Å; F170-W174 HydrophobicContact CE2-CE3 4.06Å; F170-W174 HydrophobicContact CZ-CB 4.46Å; F170-W174 HydrophobicContact CZ-CD2 4.08Å; F170-W174 AromaticContact CZ-CE3 3.29Å; F170-W174 HydrophobicContact CZ-CE3 3.29Å; F170-W174 AromaticContact CZ-CZ3 3.84Å; F170-W174 HydrophobicContact CZ-CZ3 3.84Å; F170-W174 VanDerWaalsContact O-CB 3.26Å; F170-W174 WeakPolarHBondContact O-CB 3.33Å; F170-W174 PolarHBondContact O-N 3.09Å; I171-W174 WeakPolarHBondContact O-CB 3.4Å; I171-W174 PolarHBondContact O-N 2.98Å; W174-E176 VanDerWaalsContact C-N 3.26Å; W174-E176 PolarHBondContact O-N 3.28Å; W174-A177 WeakPolarHBondContact O-CB 3.39Å; W174-A177 PolarHBondContact O-N 2.93Å; W174-A177 VanDerWaalsContact O-N 3.08Å; W174-I178 HydrophobicContact CD2-CD1 3.66Å; W174-I178 HydrophobicContact CE3-CD1 3.68Å; W174-I178 HydrophobicContact CH2-CD1 3.03Å; W174-I178 HydrophobicContact CZ2-CD1 3.05Å; W174-I178 HydrophobicContact CZ2-CG1 4.37Å; W174-I178 HydrophobicContact CZ2-CG2 4.49Å; W174-I178 HydrophobicContact CZ3-CD1 3.37Å; W174-I178 PolarHBondContact O-N 3.34Å; W174-T529 PolarHBondContact NE1-OG1 3.28Å; W174-S530 VanDerWaalsContact CD1-CA 3.48Å; W174-S530 VanDerWaalsContact NE1-N 3.19Å; W174-V533 HydrophobicContact CE3-CG1 4.32Å; W174-V533 HydrophobicContact CH2-CB 3.52Å; W174-V533 HydrophobicContact CH2-CG1 3.41Å; W174-V533 VanDerWaalsContact CH2-CG1 3.41Å; W174-V533 HydrophobicContact CH2-CG2 3.4Å; W174-V533 HydrophobicContact CZ2-CB 3.9Å; W174-V533 HydrophobicContact CZ2-CG1 4.3Å; W174-V533 HydrophobicContact CZ2-CG2 3.55Å; W174-V533 HydrophobicContact CZ3-CB 3.87Å; W174-V533 HydrophobicContact CZ3-CG1 3.42Å; W174-V533 VanDerWaalsContact CZ3-CG1 3.42Å; W174-V533 HydrophobicContact CZ3-CG2 4.26Å
175	I	70.7	Confident	70.1	Confident	16 Å²	16	27 Å²	27	8%	0.082	16%	0.155	C	C	.	.	H	α-helix	trans	-51.5	-49.9	173.5	-73	159.3	0	0	0	110.1	I171 A177 I178 L179 V465 M527	I171-I175 HydrophobicContact CG2-CD1 3.84Å; I171-I175 HydrophobicContact CG2-CG1 4.38Å; I171-I175 WeakPolarHBondContact O-CD1 3.29Å; I171-I175 WeakPolarHBondContact O-CG1 3.32Å; I171-I175 PolarHBondContact O-N 3.18Å; I175-A177 VanDerWaalsContact C-N 3.26Å; I175-A177 PolarHBondContact O-N 3.45Å; I175-I178 PolarHBondContact O-N 3.45Å; I175-L179 HydrophobicContact CG2-CD1 4.41Å; I175-L179 VanDerWaalsContact O-CB 3.32Å; I175-L179 WeakPolarHBondContact O-CB 3.44Å; I175-L179 PolarHBondContact O-N 3.27Å; I175-V465 HydrophobicContact CB-CG1 3.98Å; I175-V465 HydrophobicContact CD1-CG1 3.36Å; I175-V465 HydrophobicContact CG1-CG1 3.48Å; I175-V465 VanDerWaalsContact CG1-CG1 3.48Å; I175-V465 HydrophobicContact CG2-CB 4.1Å; I175-V465 HydrophobicContact CG2-CG1 3.27Å; I175-M527 HydrophobicContact CD1-CB 4.38Å; I175-M527 HydrophobicContact CD1-CG 3.69Å; I175-M527 HydrophobicContact CD1-SD 3.81Å; I175-M527 HydrophobicContact CG1-CB 4.02Å; I175-M527 HydrophobicContact CG1-CG 3.78Å; I175-M527 HydrophobicContact CG1-SD 4.48Å
176	E	66.9	Low	68.2	Low	36 Å²	36	30 Å²	30	17%	0.168	17%	0.17	C	C	.	.	H	α-helix	trans	-67.7	-31.5	-179.7	-66.5	-83.7	-147.4	0	0	113.1	R172 L173 W174 R204 L410	R172-E176 IonicContact CZ-OE1 3.94Å; R172-E176 VanDerWaalsContact NH1-CD 3.25Å; R172-E176 IonicContact NH1-OE1 2.66Å; R172-E176 PolarHBondContact NH1-OE1 2.79Å; R172-E176 IonicContact NH2-OE1 3.7Å; R172-E176 PolarHBondContact NH2-OE1 2.87Å; L173-E176 PolarHBondContact O-N 2.97Å; W174-E176 VanDerWaalsContact C-N 3.26Å; W174-E176 PolarHBondContact O-N 3.28Å; E176-R204 HydrophobicContact CB-CB 4.3Å; E176-R204 WeakPolarHBondContact O-CA 3.29Å; E176-R204 PolarHBondContact O-N 2.71Å; E176-R204 IonicContact OE1-CZ 3.43Å; E176-R204 IonicContact OE1-NH1 2.91Å; E176-R204 PolarHBondContact OE1-NH1 3.39Å; E176-R204 WeakPolarHBondContact OE2-CD 3.06Å; E176-L410 HydrophobicContact CB-CD2 4.08Å; E176-L410 HydrophobicContact CG-CD2 3.85Å
177	A	64.4	Low	66.4	Low	1 Å²	1	33.9 Å²	33.9	1%	0.008	18%	0.176	C	C	.	.	H	α-helix	trans	-67.7	-51.3	178.6	0	0	0	0	0	110.9	L173 W174 I175 N202 F203 M420	L173-A177 WeakPolarHBondContact O-CB 3.33Å; L173-A177 PolarHBondContact O-N 3.49Å; L173-A177 VanDerWaalsContact O-N 3.12Å; W174-A177 WeakPolarHBondContact O-CB 3.39Å; W174-A177 PolarHBondContact O-N 2.93Å; W174-A177 VanDerWaalsContact O-N 3.08Å; I175-A177 VanDerWaalsContact C-N 3.26Å; I175-A177 PolarHBondContact O-N 3.45Å; A177-N202 CarbonylContact C-O 3.57Å; A177-N202 WeakPolarHBondContact CA-O 3.3Å; A177-N202 WeakPolarHBondContact CB-O 3.48Å; A177-N202 CarbonylContact O-C 3.55Å; A177-N202 WeakPolarHBondContact O-CB 3.47Å; A177-F203 PolarHBondContact O-N 3.33Å; A177-M420 HydrophobicContact CB-CE 3.96Å
178	I	60.7	Low	64.3	Low	16 Å²	16	35.9 Å²	35.9	8%	0.082	18%	0.184	C	C	.	.	H	α-helix	trans	-117.8	-13.6	-154.8	-81.2	164.6	0	0	0	115.4	W174 I175 H180 A181 L182 N202 I526	W174-I178 HydrophobicContact CD2-CD1 3.66Å; W174-I178 HydrophobicContact CE3-CD1 3.68Å; W174-I178 HydrophobicContact CH2-CD1 3.03Å; W174-I178 HydrophobicContact CZ2-CD1 3.05Å; W174-I178 HydrophobicContact CZ2-CG1 4.37Å; W174-I178 HydrophobicContact CZ2-CG2 4.49Å; W174-I178 HydrophobicContact CZ3-CD1 3.37Å; W174-I178 PolarHBondContact O-N 3.34Å; I175-I178 PolarHBondContact O-N 3.45Å; I178-H180 PolarHBondContact O-N 3.07Å; I178-A181 PolarHBondContact O-N 2.82Å; I178-L182 HydrophobicContact CG2-CD1 3.83Å; I178-L182 HydrophobicContact CG2-CG 4.23Å; I178-N202 HydrophobicContact CG1-CB 4.02Å; I178-I526 HydrophobicContact CG2-CG2 4.24Å
179	L	53.3	Low	62.3	Low	8 Å²	8	38.3 Å²	38.3	4%	0.042	20%	0.203	C	C	.	.	H	α-helix	trans	-49.8	-28.1	-165	-155	85.5	0	0	0	115.1	I175 I462 V465 I526	I175-L179 HydrophobicContact CG2-CD1 4.41Å; I175-L179 VanDerWaalsContact O-CB 3.32Å; I175-L179 WeakPolarHBondContact O-CB 3.44Å; I175-L179 PolarHBondContact O-N 3.27Å; L179-I462 HydrophobicContact CD2-CB 3.96Å; L179-I462 HydrophobicContact CD2-CG1 3.68Å; L179-I462 HydrophobicContact CD2-CG2 4.45Å; L179-V465 HydrophobicContact CD1-CB 4.29Å; L179-V465 HydrophobicContact CD1-CG1 4.3Å; L179-V465 HydrophobicContact CD1-CG2 3.88Å; L179-V465 HydrophobicContact CD2-CG2 4.39Å; L179-I526 HydrophobicContact CB-CG2 4.49Å; L179-I526 HydrophobicContact CD1-CB 4.04Å; L179-I526 HydrophobicContact CD1-CG2 3.84Å; L179-I526 HydrophobicContact CG-CG2 4.29Å; L179-I526 WeakPolarHBondContact O-CD1 3.3Å
180	H	49.1	Very low	60.7	Low	14 Å²	14	45.1 Å²	45.1	7%	0.065	24%	0.244	C	C	.	.	H	α-helix	trans	-89.6	-34.4	-178.6	-81.9	-152.6	0	0	0	116.4	I178 L182 Y183 G184 C206 F448 L458 I462	I178-H180 PolarHBondContact O-N 3.07Å; H180-L182 PolarHBondContact O-N 3.06Å; H180-Y183 PolarHBondContact O-N 2.79Å; H180-Y183 VanDerWaalsContact O-N 3.1Å; H180-G184 PolarHBondContact O-N 3.39Å; H180-C206 PolarHBondContact CD2-SG 3.25Å; H180-C206 WeakPolarHBondContact CE1-CB 3.19Å; H180-C206 VanDerWaalsContact CE1-SG 3.51Å; H180-C206 PolarHBondContact ND1-SG 3.16Å; H180-C206 PolarHBondContact NE2-SG 3.43Å; H180-F448 HydrophobicContact CB-CD1 3.66Å; H180-F448 HydrophobicContact CB-CE1 3.32Å; H180-F448 HydrophobicContact CB-CZ 4.3Å; H180-L458 VanDerWaalsContact CD2-CD1 3.4Å; H180-L458 WeakPolarHBondContact CD2-CD1 3.38Å; H180-L458 VanDerWaalsContact CE1-CD1 3.49Å; H180-L458 WeakPolarHBondContact CE1-CD1 3.11Å; H180-L458 WeakPolarHBondContact CE1-CD2 3.39Å; H180-L458 WeakPolarHBondContact CE1-CG 3.18Å; H180-L458 VanDerWaalsContact ND1-CD2 3.28Å; H180-L458 WeakPolarHBondContact ND1-CD2 3.37Å; H180-L458 VanDerWaalsContact NE2-CD1 3.33Å; H180-L458 WeakPolarHBondContact NE2-CD1 3.42Å; H180-L458 WeakPolarHBondContact NE2-CG 3.45Å; H180-I462 WeakPolarHBondContact NE2-CD1 3.22Å; H180-I462 VanDerWaalsContact NE2-CG1 3.26Å; H180-I462 WeakPolarHBondContact NE2-CG1 3.16Å
181	A	51.1	Low	58.8	Low	34 Å²	34	47.4 Å²	47.4	28%	0.281	26%	0.264	S	S	.	.	H	α-helix	trans	-64.6	-37.4	-171.5	0	0	0	0	0	110.3	I178 F448	I178-A181 PolarHBondContact O-N 2.82Å; A181-F448 HydrophobicContact CB-CE1 4.07Å; A181-F448 HydrophobicContact CB-CZ 4.13Å
182	L	51.2	Low	56.8	Low	58 Å²	58	52.6 Å²	52.6	30%	0.304	29%	0.291	S	S	.	.	H	α-helix	trans	-76.4	-30.7	175.5	-70.7	173.3	0	0	0	112.8	I178 H180 H185 V186 I526 T529	I178-L182 HydrophobicContact CG2-CD1 3.83Å; I178-L182 HydrophobicContact CG2-CG 4.23Å; H180-L182 PolarHBondContact O-N 3.06Å; L182-H185 PolarHBondContact O-N 2.74Å; L182-V186 WeakPolarHBondContact O-CB 3.46Å; L182-V186 VanDerWaalsContact O-CG2 3.24Å; L182-V186 WeakPolarHBondContact O-CG2 3.1Å; L182-V186 PolarHBondContact O-N 3.47Å; L182-I526 HydrophobicContact CB-CD1 3.97Å; L182-I526 HydrophobicContact CB-CG1 3.73Å; L182-I526 HydrophobicContact CB-CG2 4.14Å; L182-I526 HydrophobicContact CD1-CG1 4.39Å; L182-I526 HydrophobicContact CD1-CG2 3.95Å; L182-T529 HydrophobicContact CD1-CG2 3.65Å
183	Y	48.4	Very low	54.6	Low	17 Å²	17	60.4 Å²	60.4	7%	0.067	33%	0.333	C	S	.	.	H	α-helix	trans	-63.8	-47.3	-179.5	-166.5	-94.7	0	0	0	111.9	H180 H185 V186 R187 Q457 L458 C461 D519 I522 I526	H180-Y183 PolarHBondContact O-N 2.79Å; H180-Y183 VanDerWaalsContact O-N 3.1Å; Y183-H185 PolarHBondContact O-N 2.95Å; Y183-V186 PolarHBondContact O-N 2.8Å; Y183-R187 PolarHBondContact O-N 3.06Å; Y183-Q457 HydrophobicContact CE1-CB 4.47Å; Y183-L458 HydrophobicContact CD1-CD1 3.85Å; Y183-L458 HydrophobicContact CG-CD1 4.12Å; Y183-C461 HydrophobicContact CD2-CB 4.3Å; Y183-C461 HydrophobicContact CE2-CB 4.14Å; Y183-C461 WeakPolarHBondContact CE2-SG 3.4Å; Y183-D519 PolarHBondContact OH-OD1 3.41Å; Y183-I522 HydrophobicContact CD2-CB 4.24Å; Y183-I522 HydrophobicContact CD2-CG2 3.38Å; Y183-I522 HydrophobicContact CE2-CB 4.03Å; Y183-I522 HydrophobicContact CE2-CD1 3.98Å; Y183-I522 HydrophobicContact CE2-CG2 3.64Å; Y183-I522 HydrophobicContact CG-CG2 4.47Å; Y183-I526 HydrophobicContact CD2-CD1 4.24Å
184	G	47.3	Very low	52.7	Low	42 Å²	42	67.2 Å²	67.2	43%	0.433	37%	0.365	S	S	.	.	H	α-helix	trans	-59.7	-34	174.8	0	0	0	0	0	112.8	H180 K188	H180-G184 PolarHBondContact O-N 3.39Å; G184-K188 PolarHBondContact O-N 2.62Å
185	H	49.9	Very low	51.1	Low	53 Å²	53	68 Å²	68	25%	0.245	37%	0.373	C	S	.	.	H	α-helix	trans	-76.7	-41.5	-179.6	-133.1	63.4	0	0	0	113.7	L182 Y183 R187 K188 A191	L182-H185 PolarHBondContact O-N 2.74Å; Y183-H185 PolarHBondContact O-N 2.95Å; H185-R187 PolarHBondContact O-N 2.98Å; H185-K188 CarbonylContact O-C 3.59Å; H185-K188 PolarHBondContact O-N 3.12Å; H185-K188 VanDerWaalsContact O-N 3.11Å; H185-A191 PolarHBondContact CE1-O 2.78Å
186	V	50.2	Low	49.8	Very low	84 Å²	84	73 Å²	73	51%	0.509	41%	0.407	S	S	.	.	H	α-helix	trans	-59.8	-31.9	179.6	168.4	0	0	0	0	111.1	L182 Y183 I522	L182-V186 WeakPolarHBondContact O-CB 3.46Å; L182-V186 VanDerWaalsContact O-CG2 3.24Å; L182-V186 WeakPolarHBondContact O-CG2 3.1Å; L182-V186 PolarHBondContact O-N 3.47Å; Y183-V186 PolarHBondContact O-N 2.8Å; V186-I522 HydrophobicContact CB-CG2 4.34Å; V186-I522 HydrophobicContact CG1-CD1 4.09Å; V186-I522 HydrophobicContact CG1-CG1 4.01Å; V186-I522 HydrophobicContact CG1-CG2 4.13Å; V186-I522 HydrophobicContact CG2-CG2 4.45Å
187	R	48.9	Very low	48.5	Very low	147 Å²	147	78.2 Å²	78.2	56%	0.555	44%	0.435	S	S	*	.	H	α-helix	trans	-89.7	-19.6	176.6	-126.8	176.9	-167.5	-155.4	9.9	114.6	Y183 H185	Y183-R187 PolarHBondContact O-N 3.06Å; H185-R187 PolarHBondContact O-N 2.98Å
188	K	46.2	Very low	47.4	Very low	118 Å²	118	79.9 Å²	79.9	51%	0.513	45%	0.452	S	S	.	.			trans	-135.3	86.1	179.1	-67	-173.4	-178.1	-175.4	0	111.2	G184 H185 T190	G184-K188 PolarHBondContact O-N 2.62Å; H185-K188 CarbonylContact O-C 3.59Å; H185-K188 PolarHBondContact O-N 3.12Å; H185-K188 VanDerWaalsContact O-N 3.11Å; K188-T190 PolarHBondContact O-N 3.14Å; K188-T190 VanDerWaalsContact O-N 3.15Å
189	P	46.4	Very low	46.6	Very low	95 Å²	95	86.1 Å²	86.1	62%	0.617	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.1	0.8	-175.1	26.3	-33.5	0	0	0	115.9	A191	P189-A191 VanDerWaalsContact C-N 3.31Å; P189-A191 PolarHBondContact O-N 2.88Å
190	T	51.6	Low	45.8	Very low	143 Å²	143	91 Å²	91	88%	0.877	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.4	2.1	-174.9	42.7	0	0	0	0	115.6	K188	K188-T190 PolarHBondContact O-N 3.14Å; K188-T190 VanDerWaalsContact O-N 3.15Å
191	A	46.1	Very low	45.4	Very low	52 Å²	52	95.4 Å²	95.4	43%	0.43	52%	0.524	S	S	.	.			trans	-106.4	35.8	-176	0	0	0	0	0	114.6	H185 P189 L193 Q194	H185-A191 PolarHBondContact CE1-O 2.78Å; P189-A191 VanDerWaalsContact C-N 3.31Å; P189-A191 PolarHBondContact O-N 2.88Å; A191-L193 PolarHBondContact O-N 2.94Å; A191-L193 VanDerWaalsContact O-N 3.11Å; A191-Q194 PolarHBondContact O-N 3.3Å
192	L	44.8	Very low	44.9	Very low	135 Å²	135	94.7 Å²	94.7	71%	0.707	52%	0.516	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-5.5	-169.2	-140.5	144.5	0	0	0	115.5	T195	L192-T195 VanDerWaalsContact C-OG1 3.29Å; L192-T195 PolarHBondContact O-OG1 3.18Å
193	L	38.9	Very low	44.5	Very low	171 Å²	171	92.2 Å²	92.2	90%	0.895	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.1	-17.3	-178.9	-161.3	64.6	0	0	0	113.6	A191 T195	A191-L193 PolarHBondContact O-N 2.94Å; A191-L193 VanDerWaalsContact O-N 3.11Å; L193-T195 VanDerWaalsContact C-N 3.31Å; L193-T195 PolarHBondContact O-N 3.24Å
194	Q	42.6	Very low	45	Very low	144 Å²	144	91.8 Å²	91.8	67%	0.673	50%	0.501	S	S	*	.	S	Bend	trans	-83.4	-7.6	179.2	-161.1	65.9	14.3	0	0	113	A191 C196	A191-Q194 PolarHBondContact O-N 3.3Å; Q194-C196 PolarHBondContact O-N 3.38Å
195	T	45.2	Very low	45.4	Very low	44 Å²	44	89.8 Å²	89.8	27%	0.27	48%	0.48	S	S	.	.	H	α-helix	trans	-66.3	-38.8	-169.8	3.2	0	0	0	0	113.9	L192 L193 I197 G198	L192-T195 VanDerWaalsContact C-OG1 3.29Å; L192-T195 PolarHBondContact O-OG1 3.18Å; L193-T195 VanDerWaalsContact C-N 3.31Å; L193-T195 PolarHBondContact O-N 3.24Å; T195-I197 VanDerWaalsContact C-N 3.29Å; T195-I197 PolarHBondContact O-N 3.47Å; T195-G198 PolarHBondContact O-N 3.28Å
196	C	41.8	Very low	46.1	Very low	120 Å²	120	87.9 Å²	87.9	81%	0.811	47%	0.472	S	S	*	.	H	α-helix	trans	-69.5	-22.4	-169.7	-70.5	0	0	0	0	114.5	Q194	Q194-C196 PolarHBondContact O-N 3.38Å
197	I	40.2	Very low	47.4	Very low	146 Å²	146	85.7 Å²	85.7	75%	0.749	46%	0.461	S	S	*	.	H	α-helix	trans	-93.5	-25	178	-63.4	169.9	0	0	0	111	T195	T195-I197 VanDerWaalsContact C-N 3.29Å; T195-I197 PolarHBondContact O-N 3.47Å
198	G	41.5	Very low	48.9	Very low	36 Å²	36	78.7 Å²	78.7	37%	0.371	43%	0.434	S	S	.	.	H	α-helix	trans	-76.4	-24.2	-176.9	0	0	0	0	0	115	T195 M200 N202	T195-G198 PolarHBondContact O-N 3.28Å; G198-M200 VanDerWaalsContact C-N 3.29Å; G198-M200 PolarHBondContact O-N 3.28Å; G198-N202 PolarHBondContact O-ND2 3.1Å
199	E	43.6	Very low	50.4	Low	148 Å²	148	73.2 Å²	73.2	69%	0.692	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.1	-17.8	-171	-72.7	-176.6	-176.3	0	0	114.9
200	M	37.5	Very low	51.8	Low	110 Å²	110	69.6 Å²	69.6	54%	0.542	39%	0.386	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.9	-11.5	-170.5	-159.1	160.1	84.8	0	0	115.2	G198	G198-M200 VanDerWaalsContact C-N 3.29Å; G198-M200 PolarHBondContact O-N 3.28Å
201	F	40	Very low	53.3	Low	107 Å²	107	63.5 Å²	63.5	47%	0.469	35%	0.349	S	S	.	.			trans	-142	103.9	-178	-72.1	-102.4	0	0	0	107.8	L444	F201-L444 VanDerWaalsContact C-CD2 3.49Å; F201-L444 HydrophobicContact CB-CD1 4.26Å; F201-L444 HydrophobicContact CB-CD2 3.88Å; F201-L444 WeakPolarHBondContact O-CD2 3.33Å
202	N	39.7	Very low	55.3	Low	19 Å²	19	61 Å²	61	10%	0.102	33%	0.328	C	S	.	.			trans	-155.2	126.9	164.7	-72.3	-57.3	0	0	0	107.6	A177 I178 G198 L444 F448	A177-N202 CarbonylContact C-O 3.57Å; A177-N202 WeakPolarHBondContact CA-O 3.3Å; A177-N202 WeakPolarHBondContact CB-O 3.48Å; A177-N202 CarbonylContact O-C 3.55Å; A177-N202 WeakPolarHBondContact O-CB 3.47Å; I178-N202 HydrophobicContact CG1-CB 4.02Å; G198-N202 PolarHBondContact O-ND2 3.1Å; N202-L444 VanDerWaalsContact CA-CD1 3.48Å; N202-F448 HydrophobicContact CB-CE2 4.25Å; N202-F448 HydrophobicContact CB-CZ 4.23Å; N202-F448 WeakPolarHBondContact OD1-CE2 3.21Å; N202-F448 WeakPolarHBondContact OD1-CZ 3.33Å
203	F	43.9	Very low	57.1	Low	5 Å²	5	55.5 Å²	55.5	2%	0.022	30%	0.299	C	S	.	.			trans	-161.3	100.7	-156.7	-75.7	-63.5	0	0	0	109.7	A177 P205 F411 M420 L424 A440 L444	A177-F203 PolarHBondContact O-N 3.33Å; F203-P205 VanDerWaalsContact C-N 3.31Å; F203-P205 VanDerWaalsContact O-CD 3.25Å; F203-P205 WeakPolarHBondContact O-CD 3.48Å; F203-F411 VanDerWaalsContact C-CE2 3.43Å; F203-F411 VanDerWaalsContact CA-CZ 3.4Å; F203-F411 HydrophobicContact CB-CD1 4.03Å; F203-F411 HydrophobicContact CB-CD2 3.7Å; F203-F411 HydrophobicContact CB-CE1 3.76Å; F203-F411 HydrophobicContact CB-CE2 3.4Å; F203-F411 VanDerWaalsContact CB-CE2 3.4Å; F203-F411 HydrophobicContact CB-CG 4.02Å; F203-F411 HydrophobicContact CB-CZ 3.45Å; F203-F411 VanDerWaalsContact CB-CZ 3.45Å; F203-F411 HydrophobicContact CD1-CB 4.29Å; F203-F411 AromaticContact CD1-CD1 3.15Å; F203-F411 HydrophobicContact CD1-CD1 3.15Å; F203-F411 HydrophobicContact CD1-CD2 4.14Å; F203-F411 AromaticContact CD1-CE1 3.46Å; F203-F411 HydrophobicContact CD1-CE1 3.46Å; F203-F411 VanDerWaalsContact CD1-CE1 3.46Å; F203-F411 HydrophobicContact CD1-CE2 4.39Å; F203-F411 AromaticContact CD1-CG 3.56Å; F203-F411 HydrophobicContact CD1-CG 3.56Å; F203-F411 HydrophobicContact CD1-CZ 4.08Å; F203-F411 HydrophobicContact CE1-CB 4.47Å; F203-F411 AromaticContact CE1-CD1 3.81Å; F203-F411 HydrophobicContact CE1-CD1 3.81Å; F203-F411 HydrophobicContact CE1-CE1 4.45Å; F203-F411 HydrophobicContact CE1-CG 4.17Å; F203-F411 AromaticContact CG-CD1 3.96Å; F203-F411 HydrophobicContact CG-CD1 3.96Å; F203-F411 HydrophobicContact CG-CD2 4.16Å; F203-F411 HydrophobicContact CG-CE1 4.09Å; F203-F411 HydrophobicContact CG-CE2 4.29Å; F203-F411 HydrophobicContact CG-CG 4.02Å; F203-F411 HydrophobicContact CG-CZ 4.26Å; F203-M420 HydrophobicContact CD1-CE 3.87Å; F203-M420 HydrophobicContact CD1-SD 4.29Å; F203-M420 HydrophobicContact CE1-CB 4.17Å; F203-M420 HydrophobicContact CE1-CE 3.32Å; F203-M420 HydrophobicContact CE1-CG 3.61Å; F203-M420 HydrophobicContact CE1-SD 3.18Å; F203-M420 WeakPolarHBondContact CE1-SD 3.16Å; F203-M420 HydrophobicContact CZ-CB 4.33Å; F203-M420 HydrophobicContact CZ-CE 4.14Å; F203-M420 HydrophobicContact CZ-CG 4.16Å; F203-M420 HydrophobicContact CZ-SD 3.51Å; F203-M420 VanDerWaalsContact CZ-SD 3.51Å; F203-L424 HydrophobicContact CD2-CD1 4.31Å; F203-L424 HydrophobicContact CE1-CD1 3.72Å; F203-L424 HydrophobicContact CE2-CD1 3.63Å; F203-L424 HydrophobicContact CZ-CD1 3.29Å; F203-A440 HydrophobicContact CD2-CB 4.17Å; F203-L444 HydrophobicContact CB-CD1 3.55Å; F203-L444 HydrophobicContact CD2-CD1 3.51Å; F203-L444 HydrophobicContact CG-CD1 3.97Å
204	R	59.3	Low	59.2	Low	9 Å²	9	48.4 Å²	48.4	3%	0.034	26%	0.263	C	S	.	.	S	Bend	trans	26.8	54.4	179.2	-163.7	150.7	69	-175.3	5	116	E176 F323 T406 A407 L410 F411	E176-R204 HydrophobicContact CB-CB 4.3Å; E176-R204 WeakPolarHBondContact O-CA 3.29Å; E176-R204 PolarHBondContact O-N 2.71Å; E176-R204 IonicContact OE1-CZ 3.43Å; E176-R204 IonicContact OE1-NH1 2.91Å; E176-R204 PolarHBondContact OE1-NH1 3.39Å; E176-R204 WeakPolarHBondContact OE2-CD 3.06Å; R204-F323 VanDerWaalsContact NH2-CD1 3.34Å; R204-T406 VanDerWaalsContact NH2-C 3.27Å; R204-T406 PolarHBondContact NH2-O 3.15Å; R204-A407 HydrophobicContact CB-CB 3.9Å; R204-A407 HydrophobicContact CG-CB 4.04Å; R204-A407 VanDerWaalsContact NE-CA 3.33Å; R204-A407 VanDerWaalsContact NH2-CA 3.3Å; R204-L410 VanDerWaalsContact CZ-CD2 3.41Å; R204-F411 HydrophobicContact CB-CE1 4.33Å; R204-F411 HydrophobicContact CB-CE2 4.01Å; R204-F411 HydrophobicContact CB-CZ 3.35Å
205	P	54.5	Low	61.5	Low	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.238	C	C	.	.			trans	-91.8	-17.5	-179.5	29.8	-17.9	0	0	0	111.9	F203 A208 T209 L444 S445 F448	F203-P205 VanDerWaalsContact C-N 3.31Å; F203-P205 VanDerWaalsContact O-CD 3.25Å; F203-P205 WeakPolarHBondContact O-CD 3.48Å; P205-A208 PolarHBondContact O-N 3.02Å; P205-T209 WeakPolarHBondContact O-CB 3.48Å; P205-T209 PolarHBondContact O-N 3.32Å; P205-T209 PolarHBondContact O-OG1 3.37Å; P205-L444 HydrophobicContact CB-CB 3.97Å; P205-L444 HydrophobicContact CG-CB 4.24Å; P205-S445 WeakPolarHBondContact CA-OG 3.5Å; P205-S445 VanDerWaalsContact CB-CA 3.49Å; P205-S445 VanDerWaalsContact CB-N 3.32Å; P205-F448 HydrophobicContact CB-CD2 3.38Å; P205-F448 HydrophobicContact CB-CE2 3.89Å; P205-F448 HydrophobicContact CB-CG 4.17Å; P205-F448 HydrophobicContact CG-CD2 2.97Å; P205-F448 HydrophobicContact CG-CE2 2.96Å; P205-F448 HydrophobicContact CG-CG 3.87Å; P205-F448 HydrophobicContact CG-CZ 3.82Å
206	C	65.7	Low	63.6	Low	12 Å²	12	41.1 Å²	41.1	8%	0.081	23%	0.226	C	C	.	.	H	α-helix	trans	-65.6	-53.6	-167.7	-54.4	0	0	0	0	112.9	H180 A208 T209 I210	H180-C206 PolarHBondContact CD2-SG 3.25Å; H180-C206 WeakPolarHBondContact CE1-CB 3.19Å; H180-C206 VanDerWaalsContact CE1-SG 3.51Å; H180-C206 PolarHBondContact ND1-SG 3.16Å; H180-C206 PolarHBondContact NE2-SG 3.43Å; C206-A208 VanDerWaalsContact C-N 3.29Å; C206-A208 PolarHBondContact O-N 2.89Å; C206-T209 WeakPolarHBondContact O-CB 3.18Å; C206-T209 PolarHBondContact O-N 3.06Å; C206-I210 VanDerWaalsContact O-CG1 3.27Å; C206-I210 WeakPolarHBondContact O-CG1 3.42Å; C206-I210 PolarHBondContact O-N 3.44Å
207	S	76.5	Confident	65.6	Low	38 Å²	38	40.4 Å²	40.4	27%	0.266	21%	0.209	S	C	.	.	H	α-helix	trans	-61.8	-40.8	179.5	-53	0	0	0	0	111.1	I210 T211	S207-I210 PolarHBondContact O-N 3.47Å; S207-T211 WeakPolarHBondContact O-CB 3.02Å; S207-T211 WeakPolarHBondContact O-CG2 3.33Å; S207-T211 PolarHBondContact O-N 2.95Å; S207-T211 PolarHBondContact O-OG1 2.82Å
208	A	80.1	Confident	67.8	Low	0 Å²	0	34.4 Å²	34.4	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-63.5	-45.3	176.4	0	0	0	0	0	111.2	P205 C206 T211 A212 L242 V403 I404	P205-A208 PolarHBondContact O-N 3.02Å; C206-A208 VanDerWaalsContact C-N 3.29Å; C206-A208 PolarHBondContact O-N 2.89Å; A208-T211 WeakPolarHBondContact CA-OG1 3.17Å; A208-T211 PolarHBondContact O-N 3.19Å; A208-T211 PolarHBondContact O-OG1 3.02Å; A208-A212 VanDerWaalsContact O-CB 3.22Å; A208-A212 WeakPolarHBondContact O-CB 3.46Å; A208-A212 PolarHBondContact O-N 3.37Å; A208-L242 HydrophobicContact CB-CD2 4.04Å; A208-V403 HydrophobicContact CB-CB 4.43Å; A208-V403 HydrophobicContact CB-CG1 3.86Å; A208-I404 HydrophobicContact CB-CG1 4.39Å
209	T	78.5	Confident	70.1	Confident	4 Å²	4	33.8 Å²	33.8	3%	0.025	17%	0.168	C	C	.	.	H	α-helix	trans	-58.8	-50.6	176.2	-60.5	0	0	0	0	111.4	P205 C206 T211 A212 L213 S445 F448 L449	P205-T209 WeakPolarHBondContact O-CB 3.48Å; P205-T209 PolarHBondContact O-N 3.32Å; P205-T209 PolarHBondContact O-OG1 3.37Å; C206-T209 WeakPolarHBondContact O-CB 3.18Å; C206-T209 PolarHBondContact O-N 3.06Å; T209-T211 PolarHBondContact O-N 2.84Å; T209-A212 PolarHBondContact O-N 2.83Å; T209-L213 HydrophobicContact CG2-CD1 4.21Å; T209-L213 WeakPolarHBondContact O-CG 3.47Å; T209-L213 PolarHBondContact O-N 2.82Å; T209-S445 WeakPolarHBondContact OG1-CA 3.31Å; T209-S445 PolarHBondContact OG1-O 3.24Å; T209-S445 VanDerWaalsContact OG1-O 3.08Å; T209-F448 HydrophobicContact CG2-CB 4.17Å; T209-L449 HydrophobicContact CG2-CD2 3.48Å; T209-L449 VanDerWaalsContact CG2-CD2 3.48Å; T209-L449 HydrophobicContact CG2-CG 3.86Å
210	I	76.3	Confident	72.3	Confident	19 Å²	19	27.1 Å²	27.1	10%	0.097	14%	0.137	C	C	.	.	H	α-helix	trans	-61.1	-47	179.3	-67.2	168.2	0	0	0	109.8	C206 S207 A212 L213 T214 I455 I462	C206-I210 VanDerWaalsContact O-CG1 3.27Å; C206-I210 WeakPolarHBondContact O-CG1 3.42Å; C206-I210 PolarHBondContact O-N 3.44Å; S207-I210 PolarHBondContact O-N 3.47Å; I210-A212 VanDerWaalsContact C-N 3.33Å; I210-A212 PolarHBondContact O-N 2.81Å; I210-L213 PolarHBondContact O-N 2.87Å; I210-T214 WeakPolarHBondContact O-CB 3.38Å; I210-T214 PolarHBondContact O-N 3.35Å; I210-T214 PolarHBondContact O-OG1 2.84Å; I210-I455 HydrophobicContact CG1-CG2 4.23Å; I210-I455 HydrophobicContact CG2-CG2 4.15Å; I210-I462 HydrophobicContact CD1-CD1 4.34Å
211	T	82.5	Confident	74.5	Confident	15 Å²	15	24 Å²	24	9%	0.092	12%	0.124	C	C	.	.	H	α-helix	trans	-64.2	-36.4	177.3	52.6	0	0	0	0	112.7	S207 A208 T209 T214 F215 T396 C400	S207-T211 WeakPolarHBondContact O-CB 3.02Å; S207-T211 WeakPolarHBondContact O-CG2 3.33Å; S207-T211 PolarHBondContact O-N 2.95Å; S207-T211 PolarHBondContact O-OG1 2.82Å; A208-T211 WeakPolarHBondContact CA-OG1 3.17Å; A208-T211 PolarHBondContact O-N 3.19Å; A208-T211 PolarHBondContact O-OG1 3.02Å; T209-T211 PolarHBondContact O-N 2.84Å; T211-T214 PolarHBondContact O-N 3.34Å; T211-F215 WeakPolarHBondContact O-CB 3.22Å; T211-F215 PolarHBondContact O-N 3.12Å; T211-T396 WeakPolarHBondContact O-CB 3.25Å; T211-C400 WeakPolarHBondContact OG1-CA 3.43Å; T211-C400 VanDerWaalsContact OG1-CB 3.29Å; T211-C400 WeakPolarHBondContact OG1-CB 3.45Å
212	A	88.2	Confident	76.6	Confident	0 Å²	0	21.4 Å²	21.4	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-72.1	-38.2	178.2	0	0	0	0	0	112.4	A208 T209 I210 F215 A216 A238 L242	A208-A212 VanDerWaalsContact O-CB 3.22Å; A208-A212 WeakPolarHBondContact O-CB 3.46Å; A208-A212 PolarHBondContact O-N 3.37Å; T209-A212 PolarHBondContact O-N 2.83Å; I210-A212 VanDerWaalsContact C-N 3.33Å; I210-A212 PolarHBondContact O-N 2.81Å; A212-F215 WeakPolarHBondContact O-CB 3.21Å; A212-F215 PolarHBondContact O-N 3.34Å; A212-A216 PolarHBondContact O-N 3.32Å; A212-A238 HydrophobicContact CB-CB 3.99Å; A212-A238 WeakPolarHBondContact O-CB 3.15Å; A212-L242 HydrophobicContact CB-CD1 4.08Å; A212-L242 HydrophobicContact CB-CD2 4Å; A212-L242 HydrophobicContact CB-CG 3.75Å
213	L	83.2	Confident	78.9	Confident	19 Å²	19	26.4 Å²	26.4	10%	0.099	14%	0.143	C	C	.	.	H	α-helix	trans	-64	-42.8	171.2	-77.7	172	0	0	0	111.3	T209 I210 F215 A216 K217 A238 L449 I455	T209-L213 HydrophobicContact CG2-CD1 4.21Å; T209-L213 WeakPolarHBondContact O-CG 3.47Å; T209-L213 PolarHBondContact O-N 2.82Å; I210-L213 PolarHBondContact O-N 2.87Å; L213-F215 VanDerWaalsContact C-N 3.31Å; L213-F215 PolarHBondContact O-N 3.05Å; L213-A216 PolarHBondContact O-N 3.16Å; L213-A216 VanDerWaalsContact O-N 3.17Å; L213-K217 PolarHBondContact O-N 3.18Å; L213-A238 HydrophobicContact CD2-CB 4.09Å; L213-A238 HydrophobicContact CG-CB 4.47Å; L213-L449 HydrophobicContact CD1-CD2 3.72Å; L213-L449 HydrophobicContact CD2-CD2 3.4Å; L213-L449 VanDerWaalsContact CD2-CD2 3.4Å; L213-L449 HydrophobicContact CG-CD2 3.28Å; L213-I455 HydrophobicContact CB-CD1 4.29Å; L213-I455 HydrophobicContact CD1-CD1 3.8Å; L213-I455 HydrophobicContact CD1-CG1 4.28Å
214	T	82.4	Confident	80.8	Confident	21 Å²	21	30 Å²	30	13%	0.129	16%	0.159	C	C	.	.	H	α-helix	trans	-63.7	-41.4	177.6	-47.3	0	0	0	0	110.5	I210 T211 A216 K217 Y218 T396	I210-T214 WeakPolarHBondContact O-CB 3.38Å; I210-T214 PolarHBondContact O-N 3.35Å; I210-T214 PolarHBondContact O-OG1 2.84Å; T211-T214 PolarHBondContact O-N 3.34Å; T214-A216 PolarHBondContact O-N 3.31Å; T214-K217 PolarHBondContact O-N 2.86Å; T214-Y218 HydrophobicContact CG2-CD2 3.62Å; T214-Y218 HydrophobicContact CG2-CE2 3.55Å; T214-Y218 VanDerWaalsContact O-CD2 3.28Å; T214-Y218 WeakPolarHBondContact O-CD2 3.47Å; T214-Y218 PolarHBondContact O-N 2.95Å; T214-T396 HydrophobicContact CG2-CG2 3.87Å
215	F	90	Very high	81.6	Confident	36 Å²	36	31.3 Å²	31.3	16%	0.158	18%	0.176	C	C	.	.	H	α-helix	trans	-53.6	-53.2	170	158.9	-105.3	0	0	0	111.4	T211 A212 L213 K217 Y218 A219 L237 C241 A393 T396 V397	T211-F215 WeakPolarHBondContact O-CB 3.22Å; T211-F215 PolarHBondContact O-N 3.12Å; A212-F215 WeakPolarHBondContact O-CB 3.21Å; A212-F215 PolarHBondContact O-N 3.34Å; L213-F215 VanDerWaalsContact C-N 3.31Å; L213-F215 PolarHBondContact O-N 3.05Å; F215-K217 PolarHBondContact O-N 2.71Å; F215-Y218 PolarHBondContact O-N 2.9Å; F215-A219 HydrophobicContact CD2-CB 4.3Å; F215-A219 HydrophobicContact CE2-CB 3.93Å; F215-A219 HydrophobicContact CZ-CB 4.16Å; F215-A219 WeakPolarHBondContact O-CB 3.17Å; F215-A219 PolarHBondContact O-N 3.42Å; F215-L237 HydrophobicContact CE1-CD1 4.16Å; F215-L237 HydrophobicContact CE1-CD2 4.4Å; F215-L237 HydrophobicContact CE1-CG 3.88Å; F215-C241 HydrophobicContact CD1-CB 3.65Å; F215-C241 HydrophobicContact CE1-CB 3.62Å; F215-A393 HydrophobicContact CD2-CB 3.86Å; F215-A393 HydrophobicContact CE2-CB 4.28Å; F215-T396 WeakPolarHBondContact CA-OG1 3.48Å; F215-T396 VanDerWaalsContact CB-OG1 3.23Å; F215-T396 WeakPolarHBondContact CB-OG1 3.21Å; F215-T396 PolarHBondContact N-OG1 3.2Å; F215-V397 HydrophobicContact CB-CG2 4.29Å; F215-V397 HydrophobicContact CD2-CG2 3.27Å; F215-V397 HydrophobicContact CE2-CG2 3.64Å; F215-V397 HydrophobicContact CG-CG2 3.77Å; F215-V397 HydrophobicContact CZ-CG2 4.4Å
216	A	89.3	Confident	82.4	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-60.6	-46.1	-176.5	0	0	0	0	0	111.7	A212 L213 T214 Y218 A219 L220 E234 L237 A238	A212-A216 PolarHBondContact O-N 3.32Å; L213-A216 PolarHBondContact O-N 3.16Å; L213-A216 VanDerWaalsContact O-N 3.17Å; T214-A216 PolarHBondContact O-N 3.31Å; A216-Y218 PolarHBondContact O-N 2.84Å; A216-A219 PolarHBondContact O-N 3.4Å; A216-L220 WeakPolarHBondContact O-CB 3.4Å; A216-L220 WeakPolarHBondContact O-CD1 3.41Å; A216-L220 WeakPolarHBondContact O-CG 3.17Å; A216-L220 PolarHBondContact O-N 3.5Å; A216-L220 VanDerWaalsContact O-N 3.1Å; A216-E234 HydrophobicContact CB-CB 4.45Å; A216-E234 WeakPolarHBondContact CB-O 3.34Å; A216-L237 HydrophobicContact CB-CB 3.98Å; A216-L237 HydrophobicContact CB-CD2 4.18Å; A216-L237 HydrophobicContact CB-CG 4.14Å; A216-A238 HydrophobicContact CB-CB 4.07Å
217	K	84	Confident	82.9	Confident	104 Å²	104	43 Å²	43	45%	0.452	24%	0.243	S	C	.	.	H	α-helix	trans	-57	-52	177.6	-174.6	172.6	-178	178.3	0	111.4	L213 T214 F215 L220 V221	L213-K217 PolarHBondContact O-N 3.18Å; T214-K217 PolarHBondContact O-N 2.86Å; F215-K217 PolarHBondContact O-N 2.71Å; K217-L220 PolarHBondContact O-N 3.2Å; K217-V221 WeakPolarHBondContact O-CG2 3.41Å; K217-V221 PolarHBondContact O-N 3.32Å
218	Y	86.3	Confident	82.6	Confident	20 Å²	20	49.2 Å²	49.2	8%	0.078	27%	0.273	C	S	.	.	H	α-helix	trans	-72.7	-29.2	-179.4	-77.3	-73.6	0	0	0	113.9	T214 F215 A216 L220 P222 A371 M374 P389 V392	T214-Y218 HydrophobicContact CG2-CD2 3.62Å; T214-Y218 HydrophobicContact CG2-CE2 3.55Å; T214-Y218 VanDerWaalsContact O-CD2 3.28Å; T214-Y218 WeakPolarHBondContact O-CD2 3.47Å; T214-Y218 PolarHBondContact O-N 2.95Å; F215-Y218 PolarHBondContact O-N 2.9Å; A216-Y218 PolarHBondContact O-N 2.84Å; Y218-L220 VanDerWaalsContact C-N 3.27Å; Y218-L220 PolarHBondContact O-N 2.78Å; Y218-P222 WeakPolarHBondContact O-CD 3.18Å; Y218-A371 HydrophobicContact CE1-CB 4.2Å; Y218-A371 WeakPolarHBondContact OH-CB 3.28Å; Y218-M374 HydrophobicContact CE1-CG 4.09Å; Y218-M374 HydrophobicContact CE1-SD 4.47Å; Y218-P389 HydrophobicContact CD1-CB 4.28Å; Y218-V392 HydrophobicContact CD1-CB 4.23Å; Y218-V392 HydrophobicContact CD1-CG1 4.05Å; Y218-V392 HydrophobicContact CD2-CB 4.41Å; Y218-V392 HydrophobicContact CD2-CG1 3.52Å; Y218-V392 HydrophobicContact CE1-CG1 4.16Å; Y218-V392 HydrophobicContact CE2-CG1 3.63Å; Y218-V392 HydrophobicContact CG-CB 4.15Å; Y218-V392 HydrophobicContact CG-CG1 3.74Å
219	A	90.6	Very high	82.3	Confident	23 Å²	23	52 Å²	52	19%	0.19	28%	0.284	C	S	.	.	H	α-helix	trans	-68.8	-28.1	175.8	0	0	0	0	0	112.4	F215 A216 L237 A393	F215-A219 HydrophobicContact CD2-CB 4.3Å; F215-A219 HydrophobicContact CE2-CB 3.93Å; F215-A219 HydrophobicContact CZ-CB 4.16Å; F215-A219 WeakPolarHBondContact O-CB 3.17Å; F215-A219 PolarHBondContact O-N 3.42Å; A216-A219 PolarHBondContact O-N 3.4Å; A219-L237 HydrophobicContact CB-CD2 4.05Å; A219-A393 HydrophobicContact CB-CB 4.15Å
220	L	89.2	Confident	82.1	Confident	9 Å²	9	58.3 Å²	58.3	5%	0.047	32%	0.317	C	S	.	.	H	α-helix	trans	-86.1	-23.5	-179.5	-67.7	168.2	0	0	0	113.3	A216 K217 Y218 I223 F224 Y229 T233 E234 L237	A216-L220 WeakPolarHBondContact O-CB 3.4Å; A216-L220 WeakPolarHBondContact O-CD1 3.41Å; A216-L220 WeakPolarHBondContact O-CG 3.17Å; A216-L220 PolarHBondContact O-N 3.5Å; A216-L220 VanDerWaalsContact O-N 3.1Å; K217-L220 PolarHBondContact O-N 3.2Å; Y218-L220 VanDerWaalsContact C-N 3.27Å; Y218-L220 PolarHBondContact O-N 2.78Å; L220-I223 PolarHBondContact O-N 3.36Å; L220-F224 HydrophobicContact CB-CD2 4.22Å; L220-F224 HydrophobicContact CD2-CD2 4.02Å; L220-F224 HydrophobicContact CD2-CE2 3.75Å; L220-F224 PolarHBondContact O-N 2.88Å; L220-Y229 HydrophobicContact CB-CE1 4.16Å; L220-Y229 HydrophobicContact CD1-CE1 4.49Å; L220-Y229 HydrophobicContact CD1-CE2 3.83Å; L220-T233 HydrophobicContact CD1-CG2 3.91Å; L220-T233 HydrophobicContact CD2-CG2 4.06Å; L220-E234 HydrophobicContact CD1-CG 3.87Å; L220-L237 HydrophobicContact CD1-CD2 4.27Å; L220-L237 HydrophobicContact CD2-CD2 4.01Å; L220-L237 HydrophobicContact CG-CD2 3.88Å
221	V	85.3	Confident	81.9	Confident	44 Å²	44	63.3 Å²	63.3	27%	0.267	35%	0.348	S	S	.	.	H	α-helix	trans	-52.9	-46	179.6	166.3	0	0	0	0	113.2	K217 I223 G225 M374 P389	K217-V221 WeakPolarHBondContact O-CG2 3.41Å; K217-V221 PolarHBondContact O-N 3.32Å; V221-I223 VanDerWaalsContact C-N 3.26Å; V221-I223 PolarHBondContact O-N 3.03Å; V221-G225 WeakPolarHBondContact O-CA 3.3Å; V221-G225 PolarHBondContact O-N 3.41Å; V221-M374 HydrophobicContact CG1-CE 3.98Å; V221-P389 HydrophobicContact CB-CB 4.17Å; V221-P389 HydrophobicContact CG1-CB 4.11Å; V221-P389 HydrophobicContact CG1-CG 4.3Å
222	P	84.2	Confident	81.6	Confident	53 Å²	53	65.8 Å²	65.8	34%	0.344	36%	0.364	S	S	.	.	H	α-helix	trans	-67	-25	177.9	-23.1	34.8	0	0	0	114.6	Y218 P389 I390	Y218-P222 WeakPolarHBondContact O-CD 3.18Å; P222-P389 HydrophobicContact CG-CB 4.14Å; P222-P389 HydrophobicContact CG-CG 3.64Å; P222-I390 HydrophobicContact CG-CD1 4.46Å; P222-I390 HydrophobicContact CG-CG1 3.91Å
223	I	86.1	Confident	81.5	Confident	123 Å²	123	67.9 Å²	67.9	63%	0.631	38%	0.378	S	S	*	.	H	α-helix	trans	-86.5	-45.8	-173.4	-58.5	174.3	0	0	0	110	L220 V221	L220-I223 PolarHBondContact O-N 3.36Å; V221-I223 VanDerWaalsContact C-N 3.26Å; V221-I223 PolarHBondContact O-N 3.03Å
224	F	84.9	Confident	81.5	Confident	80 Å²	80	69.9 Å²	69.9	35%	0.351	39%	0.386	S	S	.	.	H	α-helix	trans	-103.5	-13	-175.5	-65.9	-77.7	0	0	0	113	L220 D226 C227 Y229	L220-F224 HydrophobicContact CB-CD2 4.22Å; L220-F224 HydrophobicContact CD2-CD2 4.02Å; L220-F224 HydrophobicContact CD2-CE2 3.75Å; L220-F224 PolarHBondContact O-N 2.88Å; F224-D226 PolarHBondContact O-N 3.35Å; F224-C227 HydrophobicContact CB-CB 4.49Å; F224-C227 WeakPolarHBondContact O-CB 3.43Å; F224-C227 PolarHBondContact O-N 3.09Å; F224-C227 PolarHBondContact O-SG 3.14Å; F224-Y229 HydrophobicContact CB-CD1 3.73Å; F224-Y229 HydrophobicContact CB-CE1 4.3Å; F224-Y229 HydrophobicContact CD1-CD1 4.38Å; F224-Y229 AromaticContact CD2-CD1 3.84Å; F224-Y229 HydrophobicContact CD2-CD1 3.84Å; F224-Y229 HydrophobicContact CD2-CE1 4.42Å; F224-Y229 HydrophobicContact CD2-CG 4.27Å; F224-Y229 AromaticContact CG-CD1 3.71Å; F224-Y229 HydrophobicContact CG-CD1 3.71Å; F224-Y229 HydrophobicContact CG-CG 4.29Å
225	G	75.5	Confident	81.5	Confident	37 Å²	37	70.4 Å²	70.4	38%	0.381	39%	0.39	S	S	.	.	T	Hydrogen-bonded Turn	trans	59.4	-131.8	-171.2	0	0	0	0	0	110.4	V221 C227	V221-G225 WeakPolarHBondContact O-CA 3.3Å; V221-G225 PolarHBondContact O-N 3.41Å; G225-C227 VanDerWaalsContact C-N 3.3Å
226	D	70.8	Confident	81.4	Confident	171 Å²	171	74 Å²	74	91%	0.914	41%	0.41	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.7	6.8	172.6	-58.1	-45.3	0	0	0	112.8	F224	F224-D226 PolarHBondContact O-N 3.35Å
227	C	77.6	Confident	81.5	Confident	86 Å²	86	76.6 Å²	76.6	58%	0.581	42%	0.424	S	S	*	.			trans	-68.4	137.3	177.6	-58.8	0	0	0	0	110.8	F224 G225 Y229	F224-C227 HydrophobicContact CB-CB 4.49Å; F224-C227 WeakPolarHBondContact O-CB 3.43Å; F224-C227 PolarHBondContact O-N 3.09Å; F224-C227 PolarHBondContact O-SG 3.14Å; G225-C227 VanDerWaalsContact C-N 3.3Å; C227-Y229 PolarHBondContact O-N 3.45Å
228	N	69.8	Low	81.7	Confident	169 Å²	169	71.6 Å²	71.6	90%	0.904	40%	0.402	S	S	*	.			trans	-68.3	121.2	169.5	-68.8	-40.5	0	0	0	109.8
229	Y	73.4	Confident	81.8	Confident	58 Å²	58	72 Å²	72	23%	0.227	41%	0.408	C	S	.	.			trans	-104.8	160.2	168	49.5	-95.1	0	0	0	110.6	L220 F224 C227 T231 T233 E234	L220-Y229 HydrophobicContact CB-CE1 4.16Å; L220-Y229 HydrophobicContact CD1-CE1 4.49Å; L220-Y229 HydrophobicContact CD1-CE2 3.83Å; F224-Y229 HydrophobicContact CB-CD1 3.73Å; F224-Y229 HydrophobicContact CB-CE1 4.3Å; F224-Y229 HydrophobicContact CD1-CD1 4.38Å; F224-Y229 AromaticContact CD2-CD1 3.84Å; F224-Y229 HydrophobicContact CD2-CD1 3.84Å; F224-Y229 HydrophobicContact CD2-CE1 4.42Å; F224-Y229 HydrophobicContact CD2-CG 4.27Å; F224-Y229 AromaticContact CG-CD1 3.71Å; F224-Y229 HydrophobicContact CG-CD1 3.71Å; F224-Y229 HydrophobicContact CG-CG 4.29Å; C227-Y229 PolarHBondContact O-N 3.45Å; Y229-T231 PolarHBondContact O-N 3.33Å; Y229-T233 HydrophobicContact CD2-CG2 4.27Å; Y229-E234 HydrophobicContact CE2-CG 3.8Å; Y229-E234 VanDerWaalsContact OH-CD 3.29Å; Y229-E234 VanDerWaalsContact OH-CG 3.25Å; Y229-E234 WeakPolarHBondContact OH-CG 3.44Å; Y229-E234 PolarHBondContact OH-OE1 3.47Å
230	I	74.8	Confident	81.9	Confident	138 Å²	138	74.5 Å²	74.5	71%	0.708	42%	0.423	S	S	*	.			trans	-70	127.5	-172.4	-65.5	164.7	0	0	0	110.4	T233	I230-T233 WeakPolarHBondContact O-CB 3.35Å; I230-T233 PolarHBondContact O-N 2.84Å; I230-T233 PolarHBondContact O-OG1 2.93Å
231	T	71	Confident	82.2	Confident	124 Å²	124	74.7 Å²	74.7	76%	0.761	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.5	124.4	160.7	-47.5	0	0	0	0	107.8	Y229	Y229-T231 PolarHBondContact O-N 3.33Å
232	P	78	Confident	82.4	Confident	66 Å²	66	72.6 Å²	72.6	43%	0.429	41%	0.412	S	S	.	.	T	Hydrogen-bonded Turn	cis	-114.4	41.6	30.2	40.7	-33.5	0	0	0	116	E234 P235 L236	P232-E234 PolarHBondContact O-N 3.35Å; P232-P235 HydrophobicContact CB-CB 4.47Å; P232-P235 HydrophobicContact CB-CG 4.35Å; P232-P235 WeakPolarHBondContact O-CD 3.06Å; P232-L236 HydrophobicContact CB-CG 4.5Å; P232-L236 HydrophobicContact CG-CD1 3.95Å; P232-L236 HydrophobicContact CG-CG 4.16Å; P232-L236 WeakPolarHBondContact O-CB 3.22Å; P232-L236 VanDerWaalsContact O-CG 3.28Å; P232-L236 WeakPolarHBondContact O-CG 3.45Å; P232-L236 PolarHBondContact O-N 2.74Å
233	T	84.6	Confident	82.9	Confident	45 Å²	45	76.2 Å²	76.2	28%	0.276	42%	0.422	S	S	.	.	H	α-helix	trans	-55.9	-48.1	-177.1	-55.1	0	0	0	0	113.7	L220 Y229 I230 L236 L237	L220-T233 HydrophobicContact CD1-CG2 3.91Å; L220-T233 HydrophobicContact CD2-CG2 4.06Å; Y229-T233 HydrophobicContact CD2-CG2 4.27Å; I230-T233 WeakPolarHBondContact O-CB 3.35Å; I230-T233 PolarHBondContact O-N 2.84Å; I230-T233 PolarHBondContact O-OG1 2.93Å; T233-L236 PolarHBondContact O-N 3.19Å; T233-L237 PolarHBondContact O-N 3.42Å
234	E	83.7	Confident	83.3	Confident	60 Å²	60	74 Å²	74	28%	0.28	42%	0.415	S	S	.	.	H	α-helix	trans	-58	-56.4	176.5	-92.5	173.8	178.1	0	0	112.4	A216 L220 Y229 P232 L236 L237 A238	A216-E234 HydrophobicContact CB-CB 4.45Å; A216-E234 WeakPolarHBondContact CB-O 3.34Å; L220-E234 HydrophobicContact CD1-CG 3.87Å; Y229-E234 HydrophobicContact CE2-CG 3.8Å; Y229-E234 VanDerWaalsContact OH-CD 3.29Å; Y229-E234 VanDerWaalsContact OH-CG 3.25Å; Y229-E234 WeakPolarHBondContact OH-CG 3.44Å; Y229-E234 PolarHBondContact OH-OE1 3.47Å; P232-E234 PolarHBondContact O-N 3.35Å; E234-L236 VanDerWaalsContact C-N 3.3Å; E234-L236 PolarHBondContact O-N 2.62Å; E234-L237 PolarHBondContact O-N 3.47Å; E234-A238 WeakPolarHBondContact O-CB 3.06Å; E234-A238 PolarHBondContact O-N 2.88Å
235	P	83.1	Confident	83.7	Confident	32 Å²	32	70.5 Å²	70.5	21%	0.208	40%	0.4	C	S	.	.	H	α-helix	trans	-55.9	-38.9	175.5	-28.6	33	0	0	0	114.5	P232 A238 C239	P232-P235 HydrophobicContact CB-CB 4.47Å; P232-P235 HydrophobicContact CB-CG 4.35Å; P232-P235 WeakPolarHBondContact O-CD 3.06Å; P235-A238 PolarHBondContact O-N 3.22Å; P235-C239 WeakPolarHBondContact O-CB 3.35Å; P235-C239 PolarHBondContact O-N 3.33Å; P235-C239 PolarHBondContact O-SG 3.37Å
236	L	87.5	Confident	84.5	Confident	112 Å²	112	69.1 Å²	69.1	59%	0.586	38%	0.384	S	S	*	.	H	α-helix	trans	-65.9	-43	179.5	-73.1	174.5	0	0	0	111.9	P232 T233 E234 C239 C240	P232-L236 HydrophobicContact CB-CG 4.5Å; P232-L236 HydrophobicContact CG-CD1 3.95Å; P232-L236 HydrophobicContact CG-CG 4.16Å; P232-L236 WeakPolarHBondContact O-CB 3.22Å; P232-L236 VanDerWaalsContact O-CG 3.28Å; P232-L236 WeakPolarHBondContact O-CG 3.45Å; P232-L236 PolarHBondContact O-N 2.74Å; T233-L236 PolarHBondContact O-N 3.19Å; E234-L236 VanDerWaalsContact C-N 3.3Å; E234-L236 PolarHBondContact O-N 2.62Å; L236-C239 WeakPolarHBondContact O-CB 3.48Å; L236-C239 PolarHBondContact O-N 3.28Å; L236-C240 PolarHBondContact O-N 3Å
237	L	90.4	Very high	85.6	Confident	54 Å²	54	67.1 Å²	67.1	28%	0.283	37%	0.367	S	S	.	.	H	α-helix	trans	-67.8	-38.8	176.8	-177	59	0	0	0	111.7	F215 A216 A219 L220 T233 E234 C240 C241	F215-L237 HydrophobicContact CE1-CD1 4.16Å; F215-L237 HydrophobicContact CE1-CD2 4.4Å; F215-L237 HydrophobicContact CE1-CG 3.88Å; A216-L237 HydrophobicContact CB-CB 3.98Å; A216-L237 HydrophobicContact CB-CD2 4.18Å; A216-L237 HydrophobicContact CB-CG 4.14Å; A219-L237 HydrophobicContact CB-CD2 4.05Å; L220-L237 HydrophobicContact CD1-CD2 4.27Å; L220-L237 HydrophobicContact CD2-CD2 4.01Å; L220-L237 HydrophobicContact CG-CD2 3.88Å; T233-L237 PolarHBondContact O-N 3.42Å; E234-L237 PolarHBondContact O-N 3.47Å; L237-C240 WeakPolarHBondContact O-CB 3.41Å; L237-C240 PolarHBondContact O-N 3.17Å; L237-C241 PolarHBondContact O-N 3.19Å
238	A	88.8	Confident	86.3	Confident	0 Å²	0	64.5 Å²	64.5	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-61.8	-45	173.3	0	0	0	0	0	111.8	A212 L213 A216 E234 P235 C240 C241 L242 L449	A212-A238 HydrophobicContact CB-CB 3.99Å; A212-A238 WeakPolarHBondContact O-CB 3.15Å; L213-A238 HydrophobicContact CD2-CB 4.09Å; L213-A238 HydrophobicContact CG-CB 4.47Å; A216-A238 HydrophobicContact CB-CB 4.07Å; E234-A238 WeakPolarHBondContact O-CB 3.06Å; E234-A238 PolarHBondContact O-N 2.88Å; P235-A238 PolarHBondContact O-N 3.22Å; A238-C240 VanDerWaalsContact C-N 3.32Å; A238-C240 PolarHBondContact O-N 3.06Å; A238-C241 WeakPolarHBondContact O-CB 2.94Å; A238-C241 PolarHBondContact O-N 3.2Å; A238-L242 WeakPolarHBondContact O-CG 3.39Å; A238-L242 PolarHBondContact O-N 2.9Å; A238-L449 HydrophobicContact CB-CD1 3.69Å; A238-L449 HydrophobicContact CB-CD2 3.9Å
239	C	89.4	Confident	87.3	Confident	29 Å²	29	56.5 Å²	56.5	20%	0.196	30%	0.304	C	S	.	.	H	α-helix	trans	-56.1	-47	172.3	-84.2	0	0	0	0	111	P235 L236 C241 L242 F243 L449	P235-C239 WeakPolarHBondContact O-CB 3.35Å; P235-C239 PolarHBondContact O-N 3.33Å; P235-C239 PolarHBondContact O-SG 3.37Å; L236-C239 WeakPolarHBondContact O-CB 3.48Å; L236-C239 PolarHBondContact O-N 3.28Å; C239-C241 VanDerWaalsContact C-N 3.34Å; C239-C241 PolarHBondContact O-N 2.91Å; C239-L242 PolarHBondContact O-N 3.22Å; C239-F243 VanDerWaalsContact O-CD2 3.27Å; C239-F243 WeakPolarHBondContact O-CD2 2.83Å; C239-F243 PolarHBondContact O-N 2.9Å; C239-L449 HydrophobicContact CB-CD1 4.2Å; C239-L449 WeakPolarHBondContact SG-CD1 3.32Å
240	C	93	Very high	88.1	Confident	74 Å²	74	54.3 Å²	54.3	50%	0.5	30%	0.298	S	S	.	.	H	α-helix	trans	-59.5	-44.6	179.7	-158.5	0	0	0	0	111.7	L236 L237 A238 L242 F243 V244	L236-C240 PolarHBondContact O-N 3Å; L237-C240 WeakPolarHBondContact O-CB 3.41Å; L237-C240 PolarHBondContact O-N 3.17Å; A238-C240 VanDerWaalsContact C-N 3.32Å; A238-C240 PolarHBondContact O-N 3.06Å; C240-L242 PolarHBondContact O-N 2.83Å; C240-F243 PolarHBondContact O-N 3.34Å; C240-V244 WeakPolarHBondContact O-CG2 3.33Å; C240-V244 PolarHBondContact O-N 2.84Å
241	C	93.7	Very high	88.8	Confident	14 Å²	14	55 Å²	55	10%	0.095	29%	0.291	C	S	.	.	H	α-helix	trans	-58.4	-48.4	174.3	-177.6	0	0	0	0	112.1	F215 L237 A238 C239 F243 V244 L245	F215-C241 HydrophobicContact CD1-CB 3.65Å; F215-C241 HydrophobicContact CE1-CB 3.62Å; L237-C241 PolarHBondContact O-N 3.19Å; A238-C241 WeakPolarHBondContact O-CB 2.94Å; A238-C241 PolarHBondContact O-N 3.2Å; C239-C241 VanDerWaalsContact C-N 3.34Å; C239-C241 PolarHBondContact O-N 2.91Å; C241-F243 PolarHBondContact O-N 2.87Å; C241-V244 PolarHBondContact O-N 2.9Å; C241-L245 WeakPolarHBondContact O-CB 3.37Å; C241-L245 WeakPolarHBondContact O-CG 3.23Å; C241-L245 PolarHBondContact O-N 3.37Å
242	L	91.1	Very high	89.6	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-60.5	-43.6	177.5	-71.9	168.5	0	0	0	112.1	A208 A212 A238 C239 C240 L245 T246 I404 L449	A208-L242 HydrophobicContact CB-CD2 4.04Å; A212-L242 HydrophobicContact CB-CD1 4.08Å; A212-L242 HydrophobicContact CB-CD2 4Å; A212-L242 HydrophobicContact CB-CG 3.75Å; A238-L242 WeakPolarHBondContact O-CG 3.39Å; A238-L242 PolarHBondContact O-N 2.9Å; C239-L242 PolarHBondContact O-N 3.22Å; C240-L242 PolarHBondContact O-N 2.83Å; L242-L245 PolarHBondContact O-N 2.87Å; L242-T246 WeakPolarHBondContact O-CB 3.42Å; L242-T246 PolarHBondContact O-N 2.79Å; L242-T246 PolarHBondContact O-OG1 3.22Å; L242-I404 HydrophobicContact CD2-CD1 4.26Å; L242-L449 HydrophobicContact CD1-CD1 3.63Å; L242-L449 HydrophobicContact CD1-CG 4.38Å
243	F	93.2	Very high	89.9	Confident	128 Å²	128	48.1 Å²	48.1	56%	0.561	25%	0.249	S	C	*	.	H	α-helix	trans	-60	-48.2	177.1	-93	-74.5	0	0	0	111.8	C239 C240 C241 T246 F247	C239-F243 VanDerWaalsContact O-CD2 3.27Å; C239-F243 WeakPolarHBondContact O-CD2 2.83Å; C239-F243 PolarHBondContact O-N 2.9Å; C240-F243 PolarHBondContact O-N 3.34Å; C241-F243 PolarHBondContact O-N 2.87Å; F243-T246 PolarHBondContact O-N 3.25Å; F243-F247 VanDerWaalsContact O-CB 3.32Å; F243-F247 WeakPolarHBondContact O-CB 3.49Å; F243-F247 PolarHBondContact O-N 3.47Å
244	V	94.5	Very high	90.1	Very high	78 Å²	78	52.2 Å²	52.2	47%	0.473	26%	0.263	S	S	.	.	H	α-helix	trans	-62.2	-48.5	179.3	171.8	0	0	0	0	111	C240 C241 T246 F247 I248	C240-V244 WeakPolarHBondContact O-CG2 3.33Å; C240-V244 PolarHBondContact O-N 2.84Å; C241-V244 PolarHBondContact O-N 2.9Å; V244-T246 PolarHBondContact O-N 2.85Å; V244-F247 PolarHBondContact O-N 2.96Å; V244-I248 HydrophobicContact CG1-CD1 3.74Å; V244-I248 WeakPolarHBondContact O-CD1 3.32Å; V244-I248 VanDerWaalsContact O-CG1 3.25Å; V244-I248 WeakPolarHBondContact O-CG1 3.48Å; V244-I248 PolarHBondContact O-N 3.17Å
245	L	93.9	Very high	90.4	Very high	6 Å²	6	54.3 Å²	54.3	3%	0.031	27%	0.274	C	S	.	.	H	α-helix	trans	-64.9	-39.4	179.3	-68.7	179.3	0	0	0	112.2	C241 L242 I248 N249 V397 C400 N401 I404	C241-L245 WeakPolarHBondContact O-CB 3.37Å; C241-L245 WeakPolarHBondContact O-CG 3.23Å; C241-L245 PolarHBondContact O-N 3.37Å; L242-L245 PolarHBondContact O-N 2.87Å; L245-I248 PolarHBondContact O-N 3.49Å; L245-N249 WeakPolarHBondContact O-CB 3.4Å; L245-N249 PolarHBondContact O-N 3.49Å; L245-N249 PolarHBondContact O-ND2 3.24Å; L245-V397 HydrophobicContact CD1-CG1 4.22Å; L245-V397 HydrophobicContact CD2-CG1 4.17Å; L245-C400 HydrophobicContact CD1-CB 3.77Å; L245-N401 HydrophobicContact CD1-CB 4.26Å; L245-N401 HydrophobicContact CD2-CB 4.01Å; L245-I404 HydrophobicContact CB-CD1 3.65Å; L245-I404 HydrophobicContact CD1-CD1 4.27Å
246	T	91.7	Very high	90.7	Very high	8 Å²	8	52.8 Å²	52.8	5%	0.049	26%	0.264	C	S	.	.	H	α-helix	trans	-62.9	-46.6	175.8	-59.7	0	0	0	0	110.3	L242 F243 V244 I248 N249 C250 I438 L439 G442	L242-T246 WeakPolarHBondContact O-CB 3.42Å; L242-T246 PolarHBondContact O-N 2.79Å; L242-T246 PolarHBondContact O-OG1 3.22Å; F243-T246 PolarHBondContact O-N 3.25Å; V244-T246 PolarHBondContact O-N 2.85Å; T246-I248 PolarHBondContact O-N 3.23Å; T246-N249 PolarHBondContact O-N 3.42Å; T246-C250 WeakPolarHBondContact O-CB 3.02Å; T246-C250 PolarHBondContact O-N 3.11Å; T246-C250 PolarHBondContact O-SG 3.02Å; T246-I438 HydrophobicContact CG2-CG2 3.87Å; T246-L439 HydrophobicContact CG2-CD2 4.14Å; T246-G442 WeakPolarHBondContact OG1-CA 3.47Å
247	F	93.7	Very high	90.9	Very high	128 Å²	128	48 Å²	48	56%	0.561	24%	0.24	S	C	*	.	H	α-helix	trans	-58.8	-47.1	177.2	176.9	-100.5	0	0	0	112	F243 V244 N249 C250 W251	F243-F247 VanDerWaalsContact O-CB 3.32Å; F243-F247 WeakPolarHBondContact O-CB 3.49Å; F243-F247 PolarHBondContact O-N 3.47Å; V244-F247 PolarHBondContact O-N 2.96Å; F247-N249 VanDerWaalsContact C-N 3.34Å; F247-N249 PolarHBondContact O-N 3.32Å; F247-C250 WeakPolarHBondContact O-CB 3.45Å; F247-C250 PolarHBondContact O-N 2.77Å; F247-W251 HydrophobicContact CD1-CE3 4.48Å; F247-W251 AromaticContact CE1-CE3 3.61Å; F247-W251 HydrophobicContact CE1-CE3 3.61Å; F247-W251 HydrophobicContact CE1-CZ3 4.04Å; F247-W251 HydrophobicContact CZ-CE3 4.09Å; F247-W251 WeakPolarHBondContact O-CB 3.32Å; F247-W251 PolarHBondContact O-N 3.26Å
248	I	92.8	Very high	91	Very high	32 Å²	32	51.7 Å²	51.7	16%	0.164	25%	0.253	C	S	.	.	H	α-helix	trans	-60.3	-44.2	177.5	-70.3	167	0	0	0	111.1	V244 L245 T246 C250 W251 S252 M255 A256 I259	V244-I248 HydrophobicContact CG1-CD1 3.74Å; V244-I248 WeakPolarHBondContact O-CD1 3.32Å; V244-I248 VanDerWaalsContact O-CG1 3.25Å; V244-I248 WeakPolarHBondContact O-CG1 3.48Å; V244-I248 PolarHBondContact O-N 3.17Å; L245-I248 PolarHBondContact O-N 3.49Å; T246-I248 PolarHBondContact O-N 3.23Å; I248-C250 VanDerWaalsContact C-N 3.33Å; I248-C250 PolarHBondContact O-N 3.4Å; I248-W251 PolarHBondContact O-N 3.35Å; I248-S252 PolarHBondContact O-N 3.01Å; I248-M255 HydrophobicContact CG2-CB 4.28Å; I248-A256 HydrophobicContact CG2-CB 4.38Å; I248-I259 HydrophobicContact CD1-CD1 3.79Å; I248-I259 HydrophobicContact CG2-CD1 3.61Å
249	N	91.4	Very high	91.2	Very high	0 Å²	0	54.2 Å²	54.2	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-65.9	-35.9	177.9	-86.1	-90.8	0	0	0	112.1	L245 T246 F247 A256 N401 I404 L405 I438	L245-N249 WeakPolarHBondContact O-CB 3.4Å; L245-N249 PolarHBondContact O-N 3.49Å; L245-N249 PolarHBondContact O-ND2 3.24Å; T246-N249 PolarHBondContact O-N 3.42Å; F247-N249 VanDerWaalsContact C-N 3.34Å; F247-N249 PolarHBondContact O-N 3.32Å; N249-A256 WeakPolarHBondContact OD1-CB 3.42Å; N249-N401 PolarHBondContact ND2-OD1 3.39Å; N249-I404 HydrophobicContact CB-CG2 4.18Å; N249-L405 WeakPolarHBondContact OD1-CD1 3.35Å; N249-I438 HydrophobicContact CB-CD1 4.29Å; N249-I438 HydrophobicContact CB-CG2 3.73Å; N249-I438 WeakPolarHBondContact O-CD1 3.46Å
250	C	90.5	Very high	91.4	Very high	13 Å²	13	52.9 Å²	52.9	9%	0.088	26%	0.257	C	S	.	.	H	α-helix	trans	-64.8	-42.9	173.1	-73	0	0	0	0	111.7	T246 F247 I248 T433 T435 I438	T246-C250 WeakPolarHBondContact O-CB 3.02Å; T246-C250 PolarHBondContact O-N 3.11Å; T246-C250 PolarHBondContact O-SG 3.02Å; F247-C250 WeakPolarHBondContact O-CB 3.45Å; F247-C250 PolarHBondContact O-N 2.77Å; I248-C250 VanDerWaalsContact C-N 3.33Å; I248-C250 PolarHBondContact O-N 3.4Å; C250-T433 PolarHBondContact O-OG1 3.36Å; C250-T435 HydrophobicContact CB-CG2 3.97Å; C250-I438 WeakPolarHBondContact SG-CG2 3.19Å
251	W	89.2	Confident	91.5	Very high	151 Å²	151	50.5 Å²	50.5	57%	0.572	24%	0.24	S	C	*	.	H	α-helix	trans	-71.6	-48.9	-177.1	-175	5.4	0	0	0	112.4	F247 I248 F431	F247-W251 HydrophobicContact CD1-CE3 4.48Å; F247-W251 AromaticContact CE1-CE3 3.61Å; F247-W251 HydrophobicContact CE1-CE3 3.61Å; F247-W251 HydrophobicContact CE1-CZ3 4.04Å; F247-W251 HydrophobicContact CZ-CE3 4.09Å; F247-W251 WeakPolarHBondContact O-CB 3.32Å; F247-W251 PolarHBondContact O-N 3.26Å; I248-W251 PolarHBondContact O-N 3.35Å; W251-F431 AromaticContact CD1-CD1 3.87Å; W251-F431 AromaticContact CD1-CE1 3.55Å; W251-F431 AromaticContact NE1-CE1 3.97Å; W251-F431 WeakPolarHBondContact O-CB 3.39Å; W251-F431 WeakPolarHBondContact O-CD1 3.27Å; W251-F431 WeakPolarHBondContact O-CG 3.25Å
252	S	87.5	Confident	91.5	Very high	30 Å²	30	54.1 Å²	54.1	21%	0.21	26%	0.261	C	S	.	.			trans	-157.8	124	-177.9	-173.7	0	0	0	0	113.2	I248 K254 M255 A256	I248-S252 PolarHBondContact O-N 3.01Å; S252-K254 PolarHBondContact O-N 3.33Å; S252-K254 PolarHBondContact OG-N 2.87Å; S252-M255 PolarHBondContact O-N 3.44Å; S252-M255 PolarHBondContact OG-N 3.47Å; S252-A256 PolarHBondContact O-N 2.84Å
253	V	84.4	Confident	91.7	Very high	16 Å²	16	55.4 Å²	55.4	10%	0.097	27%	0.268	C	S	.	.	H	α-helix	trans	-57.5	-39.7	169.1	-177.6	0	0	0	0	110.9	M255 A256 T257 L405 R409 T433	V253-M255 VanDerWaalsContact C-N 3.34Å; V253-M255 PolarHBondContact O-N 2.98Å; V253-A256 PolarHBondContact O-N 3.28Å; V253-T257 HydrophobicContact CG1-CG2 4.24Å; V253-T257 WeakPolarHBondContact O-CG2 3.39Å; V253-T257 PolarHBondContact O-N 2.94Å; V253-T257 PolarHBondContact O-OG1 3.45Å; V253-L405 HydrophobicContact CG1-CD1 4.32Å; V253-R409 VanDerWaalsContact CG2-NH2 3.33Å; V253-T433 HydrophobicContact CG2-CG2 3.52Å
254	K	88.6	Confident	91.8	Very high	132 Å²	132	49.3 Å²	49.3	57%	0.574	24%	0.241	S	C	*	.	H	α-helix	trans	-64.6	-38.2	-179	-66.2	-177.9	-179.3	177	0	112.3	S252 T257 K258	S252-K254 PolarHBondContact O-N 3.33Å; S252-K254 PolarHBondContact OG-N 2.87Å; K254-T257 WeakPolarHBondContact CA-OG1 3.39Å; K254-T257 PolarHBondContact O-OG1 2.91Å; K254-K258 VanDerWaalsContact O-CB 3.3Å; K254-K258 WeakPolarHBondContact O-CB 3.4Å; K254-K258 PolarHBondContact O-N 3.32Å
255	M	89.1	Confident	91.9	Very high	104 Å²	104	51.7 Å²	51.7	51%	0.512	24%	0.242	S	C	.	.	H	α-helix	trans	-70	-43	175.2	-68	-59.3	-175.1	0	0	111	I248 S252 V253 T257 K258 I259	I248-M255 HydrophobicContact CG2-CB 4.28Å; S252-M255 PolarHBondContact O-N 3.44Å; S252-M255 PolarHBondContact OG-N 3.47Å; V253-M255 VanDerWaalsContact C-N 3.34Å; V253-M255 PolarHBondContact O-N 2.98Å; M255-T257 VanDerWaalsContact C-N 3.32Å; M255-T257 PolarHBondContact O-N 2.96Å; M255-K258 PolarHBondContact O-N 3.33Å; M255-I259 WeakPolarHBondContact O-CG1 3.28Å; M255-I259 PolarHBondContact O-N 3.22Å
256	A	90.4	Very high	91.8	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-58.3	-42.8	174.9	0	0	0	0	0	112.1	I248 N249 S252 V253 Q260 N401 L405	I248-A256 HydrophobicContact CG2-CB 4.38Å; N249-A256 WeakPolarHBondContact OD1-CB 3.42Å; S252-A256 PolarHBondContact O-N 2.84Å; V253-A256 PolarHBondContact O-N 3.28Å; A256-Q260 WeakPolarHBondContact O-CB 3.21Å; A256-Q260 PolarHBondContact O-N 3.11Å; A256-N401 PolarHBondContact O-ND2 3.39Å; A256-L405 HydrophobicContact CB-CD1 4.39Å
257	T	91	Very high	91.9	Very high	11 Å²	11	53.6 Å²	53.6	7%	0.067	26%	0.26	C	S	.	.	H	α-helix	trans	-70.4	-36.3	175.6	56	0	0	0	0	112.6	I90 I98 V253 K254 M255 Q260 D261 L405	I90-T257 HydrophobicContact CG1-CG2 4.31Å; I98-T257 HydrophobicContact CD1-CG2 4.38Å; V253-T257 HydrophobicContact CG1-CG2 4.24Å; V253-T257 WeakPolarHBondContact O-CG2 3.39Å; V253-T257 PolarHBondContact O-N 2.94Å; V253-T257 PolarHBondContact O-OG1 3.45Å; K254-T257 WeakPolarHBondContact CA-OG1 3.39Å; K254-T257 PolarHBondContact O-OG1 2.91Å; M255-T257 VanDerWaalsContact C-N 3.32Å; M255-T257 PolarHBondContact O-N 2.96Å; T257-Q260 VanDerWaalsContact O-CB 3.27Å; T257-Q260 WeakPolarHBondContact O-CB 3.36Å; T257-Q260 PolarHBondContact O-N 3.02Å; T257-D261 PolarHBondContact O-N 3.16Å; T257-L405 HydrophobicContact CG2-CD2 4.42Å
258	K	93.4	Very high	92	Very high	131 Å²	131	49.2 Å²	49.2	57%	0.57	24%	0.242	S	C	*	.	H	α-helix	trans	-65.2	-41.9	176.4	-174.4	179.7	-179.9	-177.3	0	111.8	K254 M255 Q260 D261 V262	K254-K258 VanDerWaalsContact O-CB 3.3Å; K254-K258 WeakPolarHBondContact O-CB 3.4Å; K254-K258 PolarHBondContact O-N 3.32Å; M255-K258 PolarHBondContact O-N 3.33Å; K258-Q260 VanDerWaalsContact C-N 3.3Å; K258-D261 PolarHBondContact O-N 3.03Å; K258-V262 WeakPolarHBondContact O-CG2 3.42Å; K258-V262 PolarHBondContact O-N 3.36Å
259	I	92.4	Very high	92	Very high	54 Å²	54	49.5 Å²	49.5	28%	0.277	25%	0.253	S	S	.	.	H	α-helix	trans	-62.6	-41.9	173.7	-72.3	159.6	0	0	0	110.1	I248 M255 D261 V262 L263	I248-I259 HydrophobicContact CD1-CD1 3.79Å; I248-I259 HydrophobicContact CG2-CD1 3.61Å; M255-I259 WeakPolarHBondContact O-CG1 3.28Å; M255-I259 PolarHBondContact O-N 3.22Å; I259-D261 VanDerWaalsContact C-N 3.34Å; I259-D261 PolarHBondContact O-N 2.78Å; I259-V262 PolarHBondContact O-N 2.66Å; I259-L263 HydrophobicContact CG2-CD1 3.6Å; I259-L263 HydrophobicContact CG2-CG 4.24Å; I259-L263 WeakPolarHBondContact O-CB 3.47Å; I259-L263 VanDerWaalsContact O-CG 3.29Å; I259-L263 WeakPolarHBondContact O-CG 2.95Å; I259-L263 PolarHBondContact O-N 3.47Å
260	Q	93.2	Very high	92.1	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-56	-48.4	173.3	-169.8	66.4	25.9	0	0	111.8	I98 A256 T257 K258 T264 G398 N401	I98-Q260 HydrophobicContact CG1-CG 3.9Å; A256-Q260 WeakPolarHBondContact O-CB 3.21Å; A256-Q260 PolarHBondContact O-N 3.11Å; T257-Q260 VanDerWaalsContact O-CB 3.27Å; T257-Q260 WeakPolarHBondContact O-CB 3.36Å; T257-Q260 PolarHBondContact O-N 3.02Å; K258-Q260 VanDerWaalsContact C-N 3.3Å; Q260-T264 VanDerWaalsContact O-CB 3.27Å; Q260-T264 WeakPolarHBondContact O-CB 3.27Å; Q260-T264 PolarHBondContact O-N 3.46Å; Q260-T264 PolarHBondContact O-OG1 3.3Å; Q260-G398 PolarHBondContact NE2-O 2.75Å; Q260-G398 VanDerWaalsContact NE2-O 3.14Å; Q260-G398 PolarHBondContact OE1-O 3.24Å; Q260-N401 PolarHBondContact OE1-ND2 3.01Å
261	D	94.7	Very high	92.3	Very high	24 Å²	24	50 Å²	50	13%	0.128	26%	0.258	C	S	.	.	H	α-helix	trans	-59.8	-52.2	-179.2	-61.5	-21.5	0	0	0	110.8	N94 T97 T257 K258 I259 L263 T264 Y265	N94-D261 PolarHBondContact ND2-OD1 3.04Å; N94-D261 PolarHBondContact ND2-OD2 3.41Å; T97-D261 WeakPolarHBondContact CB-OD1 3.21Å; T97-D261 HydrophobicContact CG2-CB 4.34Å; T97-D261 PolarHBondContact OG1-OD1 3.23Å; T257-D261 PolarHBondContact O-N 3.16Å; K258-D261 PolarHBondContact O-N 3.03Å; I259-D261 VanDerWaalsContact C-N 3.34Å; I259-D261 PolarHBondContact O-N 2.78Å; D261-L263 PolarHBondContact O-N 3.2Å; D261-T264 PolarHBondContact O-N 2.88Å; D261-Y265 HydrophobicContact CB-CE2 4.06Å; D261-Y265 WeakPolarHBondContact O-CD2 3.13Å; D261-Y265 PolarHBondContact O-N 3.34Å
262	V	95.4	Very high	92.7	Very high	90 Å²	90	46.6 Å²	46.6	55%	0.545	25%	0.25	S	C	.	.	H	α-helix	trans	-60.1	-48.6	-178.7	172.8	0	0	0	0	111.3	K258 I259 T264 Y265 A266	K258-V262 WeakPolarHBondContact O-CG2 3.42Å; K258-V262 PolarHBondContact O-N 3.36Å; I259-V262 PolarHBondContact O-N 2.66Å; V262-T264 VanDerWaalsContact C-N 3.29Å; V262-T264 PolarHBondContact O-N 2.94Å; V262-Y265 PolarHBondContact O-N 3.19Å; V262-A266 PolarHBondContact O-N 3.05Å
263	L	94.7	Very high	93	Very high	28 Å²	28	49.3 Å²	49.3	15%	0.147	26%	0.262	C	S	.	.	H	α-helix	trans	-63.4	-38.7	178.5	-68.8	173.4	0	0	0	110.8	I259 D261 A266 K267 C394 V397 G398	I259-L263 HydrophobicContact CG2-CD1 3.6Å; I259-L263 HydrophobicContact CG2-CG 4.24Å; I259-L263 WeakPolarHBondContact O-CB 3.47Å; I259-L263 VanDerWaalsContact O-CG 3.29Å; I259-L263 WeakPolarHBondContact O-CG 2.95Å; I259-L263 PolarHBondContact O-N 3.47Å; D261-L263 PolarHBondContact O-N 3.2Å; L263-A266 PolarHBondContact O-N 3.26Å; L263-K267 WeakPolarHBondContact O-CB 3.3Å; L263-K267 WeakPolarHBondContact O-CG 3.47Å; L263-K267 PolarHBondContact O-N 3.38Å; L263-C394 HydrophobicContact CD2-CB 4.5Å; L263-V397 HydrophobicContact CD1-CB 4.37Å; L263-V397 HydrophobicContact CD1-CG1 3.93Å; L263-G398 VanDerWaalsContact CD1-CA 3.47Å
264	T	95.4	Very high	93.4	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-66.7	-41.9	178.7	-54.6	0	0	0	0	112.3	T97 V100 G101 Q260 D261 V262 A266 K267 I268	T97-T264 PolarHBondContact O-OG1 3.14Å; T97-T264 VanDerWaalsContact O-OG1 3.06Å; V100-T264 HydrophobicContact CB-CG2 4.01Å; V100-T264 HydrophobicContact CG1-CG2 3.89Å; G101-T264 VanDerWaalsContact CA-OG1 3.3Å; G101-T264 WeakPolarHBondContact CA-OG1 3.37Å; Q260-T264 VanDerWaalsContact O-CB 3.27Å; Q260-T264 WeakPolarHBondContact O-CB 3.27Å; Q260-T264 PolarHBondContact O-N 3.46Å; Q260-T264 PolarHBondContact O-OG1 3.3Å; D261-T264 PolarHBondContact O-N 2.88Å; V262-T264 VanDerWaalsContact C-N 3.29Å; V262-T264 PolarHBondContact O-N 2.94Å; T264-A266 VanDerWaalsContact C-N 3.35Å; T264-K267 WeakPolarHBondContact O-CB 3.33Å; T264-K267 PolarHBondContact O-N 3.01Å; T264-I268 HydrophobicContact CG2-CD1 4.02Å; T264-I268 HydrophobicContact CG2-CG1 4.49Å; T264-I268 WeakPolarHBondContact O-CG1 3.34Å; T264-I268 PolarHBondContact O-N 2.95Å
265	Y	95.5	Very high	93.8	Very high	127 Å²	127	42.9 Å²	42.9	50%	0.498	23%	0.234	S	C	.	.	H	α-helix	trans	-63.8	-41.2	174.7	-63.6	-44.4	0	0	0	112	T97 D261 V262 K267 I268 G269	T97-Y265 HydrophobicContact CG2-CE1 4.05Å; D261-Y265 HydrophobicContact CB-CE2 4.06Å; D261-Y265 WeakPolarHBondContact O-CD2 3.13Å; D261-Y265 PolarHBondContact O-N 3.34Å; V262-Y265 PolarHBondContact O-N 3.19Å; Y265-K267 PolarHBondContact O-N 2.84Å; Y265-I268 PolarHBondContact O-N 3.17Å; Y265-G269 PolarHBondContact O-N 2.72Å
266	A	93.8	Very high	94.1	Very high	53 Å²	53	43 Å²	43	44%	0.438	24%	0.235	S	C	.	.	H	α-helix	trans	-59.7	-45.4	174.5	0	0	0	0	0	111.6	V262 L263 T264 G269 A270 F391	V262-A266 PolarHBondContact O-N 3.05Å; L263-A266 PolarHBondContact O-N 3.26Å; T264-A266 VanDerWaalsContact C-N 3.35Å; A266-G269 PolarHBondContact O-N 3.08Å; A266-A270 PolarHBondContact O-N 3.24Å; A266-F391 WeakPolarHBondContact O-CE2 3.36Å
267	K	92.6	Very high	94.3	Very high	1 Å²	1	44 Å²	44	0%	0.004	24%	0.242	C	C	.	.	H	α-helix	trans	-56.5	-50.9	175.2	-69.5	171.4	-158.4	-145.6	0	112.9	G101 I104 L263 T264 Y265 G269 A270 L271 F391 S395 S399	G101-K267 PolarHBondContact O-NZ 3.28Å; I104-K267 HydrophobicContact CB-CD 4.24Å; I104-K267 HydrophobicContact CG2-CB 4Å; I104-K267 HydrophobicContact CG2-CD 4.06Å; I104-K267 HydrophobicContact CG2-CG 4.36Å; I104-K267 VanDerWaalsContact O-CD 3.31Å; I104-K267 WeakPolarHBondContact O-CD 3.44Å; I104-K267 PolarHBondContact O-NZ 3.5Å; L263-K267 WeakPolarHBondContact O-CB 3.3Å; L263-K267 WeakPolarHBondContact O-CG 3.47Å; L263-K267 PolarHBondContact O-N 3.38Å; T264-K267 WeakPolarHBondContact O-CB 3.33Å; T264-K267 PolarHBondContact O-N 3.01Å; Y265-K267 PolarHBondContact O-N 2.84Å; K267-G269 VanDerWaalsContact C-N 3.34Å; K267-A270 PolarHBondContact O-N 3.47Å; K267-L271 WeakPolarHBondContact O-CG 3.37Å; K267-L271 PolarHBondContact O-N 3.35Å; K267-F391 WeakPolarHBondContact O-CZ 3.49Å; K267-S395 WeakPolarHBondContact CE-O 3.39Å; K267-S395 PolarHBondContact NZ-O 3.02Å; K267-S399 PolarHBondContact NZ-OG 3.34Å; K267-S399 VanDerWaalsContact NZ-OG 3.16Å
268	I	95.3	Very high	94.4	Very high	36 Å²	36	43.5 Å²	43.5	19%	0.185	24%	0.239	C	C	.	.	H	α-helix	trans	-62.4	-45.8	179.2	-67.5	168.2	0	0	0	109.7	V100 I104 T264 Y265 A270 L271 I272 I349	V100-I268 HydrophobicContact CG1-CD1 3.87Å; V100-I268 HydrophobicContact CG1-CG1 4.09Å; I104-I268 HydrophobicContact CD1-CG1 4.2Å; T264-I268 HydrophobicContact CG2-CD1 4.02Å; T264-I268 HydrophobicContact CG2-CG1 4.49Å; T264-I268 WeakPolarHBondContact O-CG1 3.34Å; T264-I268 PolarHBondContact O-N 2.95Å; Y265-I268 PolarHBondContact O-N 3.17Å; I268-A270 PolarHBondContact O-N 3.29Å; I268-L271 PolarHBondContact O-N 2.71Å; I268-I272 HydrophobicContact CG2-CD1 3.66Å; I268-I272 HydrophobicContact CG2-CG1 4.29Å; I268-I272 VanDerWaalsContact O-CG1 3.28Å; I268-I272 WeakPolarHBondContact O-CG1 3.33Å; I268-I272 PolarHBondContact O-N 3.49Å; I268-I349 HydrophobicContact CG1-CD1 4.48Å; I268-I349 HydrophobicContact CG2-CD1 4.07Å
269	G	94.2	Very high	94.5	Very high	38 Å²	38	40.5 Å²	40.5	39%	0.392	23%	0.228	S	C	.	.	H	α-helix	trans	-56.8	-45.3	179.5	0	0	0	0	0	113	Y265 A266 K267 I272 L273	Y265-G269 PolarHBondContact O-N 2.72Å; A266-G269 PolarHBondContact O-N 3.08Å; K267-G269 VanDerWaalsContact C-N 3.34Å; G269-I272 PolarHBondContact O-N 2.6Å; G269-L273 PolarHBondContact O-N 2.79Å
270	A	92.6	Very high	94.6	Very high	24 Å²	24	41.5 Å²	41.5	20%	0.198	24%	0.237	C	C	.	.	H	α-helix	trans	-79.2	-27.4	-179.7	0	0	0	0	0	114	A266 K267 I268 I272 L273 I274 F391	A266-A270 PolarHBondContact O-N 3.24Å; K267-A270 PolarHBondContact O-N 3.47Å; I268-A270 PolarHBondContact O-N 3.29Å; A270-I272 VanDerWaalsContact C-N 3.35Å; A270-L273 WeakPolarHBondContact O-CB 3.15Å; A270-L273 PolarHBondContact O-N 3.41Å; A270-I274 WeakPolarHBondContact O-CG1 3.24Å; A270-I274 PolarHBondContact O-N 3.07Å; A270-F391 HydrophobicContact CB-CD1 3.91Å; A270-F391 HydrophobicContact CB-CD2 3.33Å; A270-F391 HydrophobicContact CB-CE1 3.65Å; A270-F391 HydrophobicContact CB-CE2 3.06Å; A270-F391 HydrophobicContact CB-CG 3.76Å; A270-F391 HydrophobicContact CB-CZ 3.24Å
271	L	95.7	Very high	94.4	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-64.9	-40.2	166.7	-72	176	0	0	0	111.5	I104 I108 F109 K267 I268 L273 I274 V275 I349 Y350 T353	I104-L271 HydrophobicContact CD1-CD1 3.92Å; I104-L271 HydrophobicContact CG1-CD1 4.4Å; I104-L271 HydrophobicContact CG2-CD1 3.69Å; I108-L271 HydrophobicContact CG2-CD2 4.3Å; F109-L271 HydrophobicContact CE1-CD2 3.6Å; F109-L271 HydrophobicContact CZ-CD2 3.9Å; F109-L271 HydrophobicContact CZ-CG 4.46Å; K267-L271 WeakPolarHBondContact O-CG 3.37Å; K267-L271 PolarHBondContact O-N 3.35Å; I268-L271 PolarHBondContact O-N 2.71Å; L271-L273 VanDerWaalsContact C-N 3.29Å; L271-L273 PolarHBondContact O-N 2.89Å; L271-I274 HydrophobicContact CD2-CD1 4.31Å; L271-I274 PolarHBondContact O-N 2.78Å; L271-V275 WeakPolarHBondContact O-CB 3.48Å; L271-V275 VanDerWaalsContact O-CG2 3.26Å; L271-V275 WeakPolarHBondContact O-CG2 3.33Å; L271-V275 PolarHBondContact O-N 3Å; L271-I349 HydrophobicContact CB-CG2 3.65Å; L271-I349 HydrophobicContact CD1-CG2 3.53Å; L271-I349 HydrophobicContact CG-CG2 4.17Å; L271-Y350 HydrophobicContact CD1-CE1 4.48Å; L271-T353 HydrophobicContact CD2-CG2 3.98Å
272	I	96.1	Very high	94.2	Very high	79 Å²	79	46.7 Å²	46.7	41%	0.405	26%	0.263	S	S	.	.	H	α-helix	trans	-59.8	-42.7	172.4	-70.1	168.5	0	0	0	110.3	I268 G269 A270 I274 V275 L276	I268-I272 HydrophobicContact CG2-CD1 3.66Å; I268-I272 HydrophobicContact CG2-CG1 4.29Å; I268-I272 VanDerWaalsContact O-CG1 3.28Å; I268-I272 WeakPolarHBondContact O-CG1 3.33Å; I268-I272 PolarHBondContact O-N 3.49Å; G269-I272 PolarHBondContact O-N 2.6Å; A270-I272 VanDerWaalsContact C-N 3.35Å; I272-I274 PolarHBondContact O-N 3.29Å; I272-V275 PolarHBondContact O-N 3.19Å; I272-L276 HydrophobicContact CG2-CD1 3.86Å; I272-L276 HydrophobicContact CG2-CG 4.13Å; I272-L276 WeakPolarHBondContact O-CB 3.47Å; I272-L276 VanDerWaalsContact O-CG 3.3Å; I272-L276 WeakPolarHBondContact O-CG 3.49Å; I272-L276 PolarHBondContact O-N 3.17Å
273	L	93.9	Very high	94	Very high	88 Å²	88	46.7 Å²	46.7	46%	0.461	27%	0.273	S	S	.	.	H	α-helix	trans	-60.9	-43.4	176.3	-179.3	147.5	0	0	0	112.1	G269 A270 L271 T277 Y381	G269-L273 PolarHBondContact O-N 2.79Å; A270-L273 WeakPolarHBondContact O-CB 3.15Å; A270-L273 PolarHBondContact O-N 3.41Å; L271-L273 VanDerWaalsContact C-N 3.29Å; L271-L273 PolarHBondContact O-N 2.89Å; L273-T277 VanDerWaalsContact O-CB 3.29Å; L273-T277 WeakPolarHBondContact O-CB 3.44Å; L273-T277 PolarHBondContact O-N 3.25Å; L273-T277 PolarHBondContact O-OG1 3.48Å; L273-Y381 HydrophobicContact CD2-CE1 4.26Å; L273-Y381 HydrophobicContact CD2-CE2 4.07Å; L273-Y381 WeakPolarHBondContact CD2-OH 3.37Å
274	I	94.1	Very high	93.8	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-60.3	-47.8	173.3	-69.7	167.7	0	0	0	110.3	F109 A270 L271 I272 T277 G278 T353 A356 F357 F376 M388	F109-I274 HydrophobicContact CE1-CD1 4.46Å; A270-I274 WeakPolarHBondContact O-CG1 3.24Å; A270-I274 PolarHBondContact O-N 3.07Å; L271-I274 HydrophobicContact CD2-CD1 4.31Å; L271-I274 PolarHBondContact O-N 2.78Å; I272-I274 PolarHBondContact O-N 3.29Å; I274-T277 PolarHBondContact O-N 3.26Å; I274-G278 PolarHBondContact O-N 3.43Å; I274-T353 HydrophobicContact CG2-CG2 4.12Å; I274-A356 HydrophobicContact CG2-CB 4.17Å; I274-F357 HydrophobicContact CG2-CD1 4.32Å; I274-F357 HydrophobicContact CG2-CE1 3.88Å; I274-F376 HydrophobicContact CB-CE1 4.36Å; I274-F376 HydrophobicContact CG1-CE1 4.26Å; I274-F376 HydrophobicContact CG2-CD1 4.31Å; I274-F376 HydrophobicContact CG2-CE1 3.91Å; I274-F376 HydrophobicContact CG2-CZ 4.02Å; I274-M388 HydrophobicContact CD1-CE 3.72Å; I274-M388 HydrophobicContact CD1-SD 3.96Å; I274-M388 HydrophobicContact CG1-CE 3.82Å
275	V	96.4	Very high	93.3	Very high	13 Å²	13	59.9 Å²	59.9	8%	0.079	33%	0.332	C	S	.	.	H	α-helix	trans	-58.4	-52.3	179	168.5	0	0	0	0	111.2	L271 I272 T277 G278 L279 L352	L271-V275 WeakPolarHBondContact O-CB 3.48Å; L271-V275 VanDerWaalsContact O-CG2 3.26Å; L271-V275 WeakPolarHBondContact O-CG2 3.33Å; L271-V275 PolarHBondContact O-N 3Å; I272-V275 PolarHBondContact O-N 3.19Å; V275-T277 VanDerWaalsContact C-N 3.28Å; V275-T277 PolarHBondContact O-N 3.43Å; V275-G278 PolarHBondContact O-N 3.41Å; V275-L279 HydrophobicContact CG1-CD1 3.76Å; V275-L279 HydrophobicContact CG1-CG 4.26Å; V275-L279 WeakPolarHBondContact O-CB 3.49Å; V275-L279 VanDerWaalsContact O-CG 3.26Å; V275-L279 WeakPolarHBondContact O-CG 3.36Å; V275-L279 PolarHBondContact O-N 3.5Å; V275-L352 HydrophobicContact CB-CB 4.45Å; V275-L352 HydrophobicContact CG1-CB 3.81Å; V275-L352 HydrophobicContact CG1-CD1 4.17Å; V275-L352 HydrophobicContact CG2-CB 3.7Å
276	L	96.2	Very high	92.7	Very high	105 Å²	105	59.4 Å²	59.4	55%	0.55	35%	0.345	S	S	.	.	H	α-helix	trans	-60.7	-39.4	179	-69.1	177.3	0	0	0	111.8	I272 T280	I272-L276 HydrophobicContact CG2-CD1 3.86Å; I272-L276 HydrophobicContact CG2-CG 4.13Å; I272-L276 WeakPolarHBondContact O-CB 3.47Å; I272-L276 VanDerWaalsContact O-CG 3.3Å; I272-L276 WeakPolarHBondContact O-CG 3.49Å; I272-L276 PolarHBondContact O-N 3.17Å; L276-T280 WeakPolarHBondContact O-CB 2.99Å; L276-T280 VanDerWaalsContact O-CG2 3.28Å; L276-T280 WeakPolarHBondContact O-CG2 3.28Å; L276-T280 PolarHBondContact O-N 3.23Å; L276-T280 PolarHBondContact O-OG1 3.45Å
277	T	93.9	Very high	92.3	Very high	22 Å²	22	57.5 Å²	57.5	14%	0.135	33%	0.329	C	S	.	.	H	α-helix	trans	-65.4	-47.7	177.3	-57.2	0	0	0	0	111.1	L273 I274 V275 L279 T280 M281 F376 V380 Y381	L273-T277 VanDerWaalsContact O-CB 3.29Å; L273-T277 WeakPolarHBondContact O-CB 3.44Å; L273-T277 PolarHBondContact O-N 3.25Å; L273-T277 PolarHBondContact O-OG1 3.48Å; I274-T277 PolarHBondContact O-N 3.26Å; V275-T277 VanDerWaalsContact C-N 3.28Å; V275-T277 PolarHBondContact O-N 3.43Å; T277-L279 PolarHBondContact O-N 3.13Å; T277-T280 WeakPolarHBondContact CA-OG1 3.36Å; T277-T280 PolarHBondContact O-N 2.86Å; T277-T280 PolarHBondContact O-OG1 3.1Å; T277-M281 VanDerWaalsContact O-CG 3.31Å; T277-M281 WeakPolarHBondContact O-CG 3.44Å; T277-M281 PolarHBondContact O-N 3.42Å; T277-F376 HydrophobicContact CG2-CE1 4.32Å; T277-F376 HydrophobicContact CG2-CZ 4Å; T277-V380 HydrophobicContact CG2-CB 4.31Å; T277-V380 HydrophobicContact CG2-CG1 3.38Å; T277-Y381 VanDerWaalsContact CB-OH 3.25Å; T277-Y381 WeakPolarHBondContact CB-OH 3.47Å; T277-Y381 HydrophobicContact CG2-CE1 3.78Å; T277-Y381 WeakPolarHBondContact CG2-OH 3.41Å; T277-Y381 PolarHBondContact OG1-OH 3Å
278	G	94	Very high	91.9	Very high	0 Å²	0	62 Å²	62	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-65.7	-39.6	178.7	0	0	0	0	0	113	I274 V275 M281 L282 A359	I274-G278 PolarHBondContact O-N 3.43Å; V275-G278 PolarHBondContact O-N 3.41Å; G278-M281 PolarHBondContact O-N 3.38Å; G278-L282 WeakPolarHBondContact O-CB 3.17Å; G278-L282 PolarHBondContact O-N 2.77Å; G278-A359 WeakPolarHBondContact O-CB 3.46Å
279	L	94.2	Very high	91.4	Very high	68 Å²	68	60.7 Å²	60.7	36%	0.356	35%	0.35	S	S	.	.	H	α-helix	trans	-67.9	-38.3	177.4	-68.2	179	0	0	0	112.6	V275 T277 L282 A283 I355	V275-L279 HydrophobicContact CG1-CD1 3.76Å; V275-L279 HydrophobicContact CG1-CG 4.26Å; V275-L279 WeakPolarHBondContact O-CB 3.49Å; V275-L279 VanDerWaalsContact O-CG 3.26Å; V275-L279 WeakPolarHBondContact O-CG 3.36Å; V275-L279 PolarHBondContact O-N 3.5Å; T277-L279 PolarHBondContact O-N 3.13Å; L279-L282 PolarHBondContact O-N 2.91Å; L279-A283 WeakPolarHBondContact O-CB 3.34Å; L279-A283 PolarHBondContact O-N 3.38Å; L279-I355 HydrophobicContact CD2-CG2 4.31Å
280	T	94.1	Very high	91.2	Very high	75 Å²	75	61.7 Å²	61.7	46%	0.46	34%	0.343	S	S	.	.	H	α-helix	trans	-66.9	-40.2	174.1	49.4	0	0	0	0	111.4	L276 T277 L282 A283 V284	L276-T280 WeakPolarHBondContact O-CB 2.99Å; L276-T280 VanDerWaalsContact O-CG2 3.28Å; L276-T280 WeakPolarHBondContact O-CG2 3.28Å; L276-T280 PolarHBondContact O-N 3.23Å; L276-T280 PolarHBondContact O-OG1 3.45Å; T277-T280 WeakPolarHBondContact CA-OG1 3.36Å; T277-T280 PolarHBondContact O-N 2.86Å; T277-T280 PolarHBondContact O-OG1 3.1Å; T280-L282 PolarHBondContact O-N 3.25Å; T280-A283 PolarHBondContact O-N 3.1Å; T280-V284 VanDerWaalsContact O-CG2 3.31Å; T280-V284 WeakPolarHBondContact O-CG2 3.4Å; T280-V284 PolarHBondContact O-N 3.09Å
281	M	90.1	Very high	90.9	Very high	80 Å²	80	66.6 Å²	66.6	39%	0.394	36%	0.362	S	S	.	.	H	α-helix	trans	-61.1	-43	173.4	-70.9	-63.3	106	0	0	112.2	T277 G278 A283 V284 R285 V360	T277-M281 VanDerWaalsContact O-CG 3.31Å; T277-M281 WeakPolarHBondContact O-CG 3.44Å; T277-M281 PolarHBondContact O-N 3.42Å; G278-M281 PolarHBondContact O-N 3.38Å; M281-A283 VanDerWaalsContact C-N 3.31Å; M281-A283 PolarHBondContact O-N 2.84Å; M281-V284 PolarHBondContact O-N 3.13Å; M281-R285 PolarHBondContact O-N 3.47Å; M281-R285 VanDerWaalsContact O-O 3.13Å; M281-V360 HydrophobicContact CB-CG2 4.12Å; M281-V360 HydrophobicContact CG-CG2 4.12Å
282	L	90.5	Very high	90.5	Very high	54 Å²	54	71.7 Å²	71.7	28%	0.283	39%	0.389	S	S	.	.	H	α-helix	trans	-63.3	-35.7	176.8	-173.1	60.4	0	0	0	112.7	G278 L279 T280 F290 A359	G278-L282 WeakPolarHBondContact O-CB 3.17Å; G278-L282 PolarHBondContact O-N 2.77Å; L279-L282 PolarHBondContact O-N 2.91Å; T280-L282 PolarHBondContact O-N 3.25Å; L282-F290 HydrophobicContact CD1-CD2 3.62Å; L282-F290 HydrophobicContact CD1-CE2 3.89Å; L282-F290 HydrophobicContact CD2-CD2 4.32Å; L282-F290 HydrophobicContact CD2-CE2 4.03Å; L282-A359 HydrophobicContact CB-CB 3.99Å; L282-A359 HydrophobicContact CD1-CB 4.4Å
283	A	90.2	Very high	90.2	Very high	90 Å²	90	69.8 Å²	69.8	74%	0.744	38%	0.382	S	S	*	.	H	α-helix	trans	-72.4	-31.7	177.4	0	0	0	0	0	112.9	L279 T280 M281	L279-A283 WeakPolarHBondContact O-CB 3.34Å; L279-A283 PolarHBondContact O-N 3.38Å; T280-A283 PolarHBondContact O-N 3.1Å; M281-A283 VanDerWaalsContact C-N 3.31Å; M281-A283 PolarHBondContact O-N 2.84Å
284	V	90.6	Very high	90.2	Very high	109 Å²	109	71.1 Å²	71.1	66%	0.661	39%	0.385	S	S	*	.	H	α-helix	trans	-84.3	-37.7	-179.9	177.6	0	0	0	0	111.6	T280 M281	T280-V284 VanDerWaalsContact O-CG2 3.31Å; T280-V284 WeakPolarHBondContact O-CG2 3.4Å; T280-V284 PolarHBondContact O-N 3.09Å; M281-V284 PolarHBondContact O-N 3.13Å
285	R	84.9	Confident	90	Very high	195 Å²	195	77.6 Å²	77.6	74%	0.736	42%	0.415	S	S	*	.	S	Bend	trans	-136.8	124.7	180	-67.9	-175.1	179.9	171.7	-0.5	110.3	M281 S287	M281-R285 PolarHBondContact O-N 3.47Å; M281-R285 VanDerWaalsContact O-O 3.13Å; R285-S287 PolarHBondContact O-N 3.2Å
286	P	82.9	Confident	89.5	Confident	118 Å²	118	79.8 Å²	79.8	77%	0.766	44%	0.44	S	S	*	.			trans	-55.1	129.2	167.9	-23.3	33.6	0	0	0	109.9
287	S	85.6	Confident	89.4	Confident	13 Å²	13	77.1 Å²	77.1	9%	0.091	43%	0.428	C	S	.	.			trans	-89.5	133.1	178.1	70.7	0	0	0	0	110.4	R285 S289 F290 A359	R285-S287 PolarHBondContact O-N 3.2Å; S287-S289 PolarHBondContact O-N 3.45Å; S287-S289 VanDerWaalsContact O-N 3.09Å; S287-F290 PolarHBondContact O-N 3.37Å; S287-F290 WeakPolarHBondContact OG-CD2 3.45Å; S287-F290 WeakPolarHBondContact OG-CE2 3.39Å; S287-A359 VanDerWaalsContact CB-O 3.31Å; S287-A359 WeakPolarHBondContact CB-O 3.38Å
288	V	84.3	Confident	89.1	Confident	94 Å²	94	77 Å²	77	57%	0.57	43%	0.428	S	S	*	.	G	3₁₀ helix	trans	-54.2	-32.5	177.9	-175.1	0	0	0	0	112.3	F290 E291	V288-F290 PolarHBondContact O-N 3.07Å; V288-F290 VanDerWaalsContact O-N 3.08Å; V288-E291 PolarHBondContact O-N 3Å; V288-E291 VanDerWaalsContact O-N 3.16Å
289	S	86.1	Confident	88.8	Confident	9 Å²	9	83 Å²	83	6%	0.063	47%	0.465	C	S	.	.	G	3₁₀ helix	trans	-59	-20	177.1	-56.6	0	0	0	0	114.6	V122 S287 Y358 I361 P362 A363	V122-S289 WeakPolarHBondContact CG2-O 3.16Å; S287-S289 PolarHBondContact O-N 3.45Å; S287-S289 VanDerWaalsContact O-N 3.09Å; S289-Y358 VanDerWaalsContact CB-O 3.25Å; S289-Y358 WeakPolarHBondContact CB-O 3.45Å; S289-Y358 PolarHBondContact OG-O 2.92Å; S289-Y358 VanDerWaalsContact OG-O 3.05Å; S289-I361 PolarHBondContact OG-O 3.25Å; S289-I361 VanDerWaalsContact OG-O 3.1Å; S289-P362 WeakPolarHBondContact OG-CA 3.49Å; S289-A363 PolarHBondContact OG-N 3.42Å
290	F	89.4	Confident	88.5	Confident	59 Å²	59	82.8 Å²	82.8	26%	0.259	46%	0.464	S	S	.	.	G	3₁₀ helix	trans	-107.1	3	180	-64.8	-54.4	0	0	0	114	V122 L126 L282 S287 V288 I355 A359	V122-F290 HydrophobicContact CG1-CD1 4.08Å; V122-F290 HydrophobicContact CG1-CE1 3.76Å; L126-F290 HydrophobicContact CD1-CE1 4.1Å; L282-F290 HydrophobicContact CD1-CD2 3.62Å; L282-F290 HydrophobicContact CD1-CE2 3.89Å; L282-F290 HydrophobicContact CD2-CD2 4.32Å; L282-F290 HydrophobicContact CD2-CE2 4.03Å; S287-F290 PolarHBondContact O-N 3.37Å; S287-F290 WeakPolarHBondContact OG-CD2 3.45Å; S287-F290 WeakPolarHBondContact OG-CE2 3.39Å; V288-F290 PolarHBondContact O-N 3.07Å; V288-F290 VanDerWaalsContact O-N 3.08Å; F290-I355 HydrophobicContact CE2-CG2 4.47Å; F290-I355 HydrophobicContact CZ-CG2 4.02Å; F290-A359 HydrophobicContact CE2-CB 4.34Å
291	E	86.1	Confident	87.8	Confident	128 Å²	128	83.4 Å²	83.4	60%	0.598	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.9	-50.7	177	-70.4	179.1	-178.5	0	0	111.1	V288	V288-E291 PolarHBondContact O-N 3Å; V288-E291 VanDerWaalsContact O-N 3.16Å
292	N	87.9	Confident	87.4	Confident	106 Å²	106	86.5 Å²	86.5	57%	0.567	48%	0.477	S	S	*	.	S	Bend	trans	-126.4	75.1	173.5	-64.8	-40.1	0	0	0	110.6	F294 E295	N292-F294 PolarHBondContact O-N 3.37Å; N292-E295 HydrophobicContact CB-CB 3.87Å; N292-E295 WeakPolarHBondContact CB-OE2 3.47Å; N292-E295 PolarHBondContact ND2-OE2 2.92Å; N292-E295 VanDerWaalsContact ND2-OE2 3.15Å; N292-E295 WeakPolarHBondContact O-CB 3.42Å; N292-E295 PolarHBondContact O-N 2.71Å; N292-E295 VanDerWaalsContact O-N 3.1Å
293	P	89.8	Confident	87.1	Confident	39 Å²	39	86.4 Å²	86.4	25%	0.253	48%	0.477	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.2	-22.7	-168.3	24	-32.9	0	0	0	113.5	S121 V122 G123	S121-P293 VanDerWaalsContact CB-O 3.31Å; S121-P293 WeakPolarHBondContact CB-O 3.47Å; V122-P293 HydrophobicContact CB-CB 4.47Å; V122-P293 PolarHBondContact N-O 2.89Å; G123-P293 PolarHBondContact N-O 3.04Å
294	F	93.3	Very high	86.9	Confident	117 Å²	117	84.6 Å²	84.6	51%	0.513	45%	0.454	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.5	5.4	-179.1	-66.6	-80.2	0	0	0	114.1	I127 N292 T297	I127-F294 HydrophobicContact CD1-CE1 3.8Å; I127-F294 HydrophobicContact CD1-CZ 4.05Å; N292-F294 PolarHBondContact O-N 3.37Å; F294-T297 WeakPolarHBondContact CA-OG1 3.34Å; F294-T297 WeakPolarHBondContact O-CB 3.49Å; F294-T297 PolarHBondContact O-N 3.07Å; F294-T297 PolarHBondContact O-OG1 3.43Å
295	E	88.9	Confident	86.3	Confident	136 Å²	136	79.4 Å²	79.4	64%	0.636	42%	0.423	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.8	136.8	174.4	-170.4	170.8	178	0	0	110.5	S121 N292 T297	S121-E295 WeakPolarHBondContact CB-O 3.23Å; N292-E295 HydrophobicContact CB-CB 3.87Å; N292-E295 WeakPolarHBondContact CB-OE2 3.47Å; N292-E295 PolarHBondContact ND2-OE2 2.92Å; N292-E295 VanDerWaalsContact ND2-OE2 3.15Å; N292-E295 WeakPolarHBondContact O-CB 3.42Å; N292-E295 PolarHBondContact O-N 2.71Å; N292-E295 VanDerWaalsContact O-N 3.1Å; E295-T297 VanDerWaalsContact C-N 3.26Å; E295-T297 PolarHBondContact O-N 2.64Å
296	G	86.7	Confident	86.1	Confident	59 Å²	59	71.8 Å²	71.8	61%	0.608	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	73.1	9.4	-178.4	0	0	0	0	0	115.6	G120 S298	G120-G296 CarbonylContact C-O 3.39Å; G120-G296 WeakPolarHBondContact CA-O 3.39Å; G120-G296 CarbonylContact O-C 3.55Å; G296-S298 PolarHBondContact O-N 3.43Å
297	T	93.2	Very high	86.3	Confident	48 Å²	48	66.2 Å²	66.2	29%	0.294	36%	0.36	S	S	.	.			trans	-53.3	122.3	-179.1	-62.6	0	0	0	0	111.4	S121 L124 F294 E295	S121-T297 WeakPolarHBondContact CB-OG1 3.49Å; S121-T297 PolarHBondContact OG-OG1 3.01Å; L124-T297 HydrophobicContact CB-CG2 3.99Å; L124-T297 HydrophobicContact CD2-CG2 3.67Å; L124-T297 HydrophobicContact CG-CG2 4.38Å; F294-T297 WeakPolarHBondContact CA-OG1 3.34Å; F294-T297 WeakPolarHBondContact O-CB 3.49Å; F294-T297 PolarHBondContact O-N 3.07Å; F294-T297 PolarHBondContact O-OG1 3.43Å; E295-T297 VanDerWaalsContact C-N 3.26Å; E295-T297 PolarHBondContact O-N 2.64Å
298	S	89.5	Confident	86.3	Confident	21 Å²	21	66.3 Å²	66.3	15%	0.147	36%	0.359	C	S	.	.			trans	-68.5	137.2	174.2	-174.6	0	0	0	0	110.7	Y118 S119 G296 D300 D303	Y118-S298 WeakPolarHBondContact O-CB 3.26Å; S119-S298 PolarHBondContact O-N 3.24Å; G296-S298 PolarHBondContact O-N 3.43Å; S298-D300 PolarHBondContact OG-N 3.03Å; S298-D303 WeakPolarHBondContact OG-CB 3.49Å; S298-D303 PolarHBondContact OG-OD2 3.25Å
299	T	87.7	Confident	86	Confident	126 Å²	126	62.5 Å²	62.5	77%	0.773	34%	0.335	S	S	*	.			trans	-110.6	-5.1	177.4	54.8	0	0	0	0	112.4	P301	T299-P301 WeakPolarHBondContact O-CD 3.42Å
300	D	86.6	Confident	85.8	Confident	63 Å²	63	63.4 Å²	63.4	34%	0.337	34%	0.341	S	S	.	.			trans	-74.4	122.9	177.6	-169.3	-24.4	0	0	0	109.5	S298 R302 D303 I304	S298-D300 PolarHBondContact OG-N 3.03Å; D300-R302 PolarHBondContact O-N 3.11Å; D300-R302 VanDerWaalsContact O-N 3.09Å; D300-R302 WeakPolarHBondContact OD1-CB 3.19Å; D300-R302 WeakPolarHBondContact OD1-CG 3.26Å; D300-R302 PolarHBondContact OD1-N 3.36Å; D300-D303 HydrophobicContact CB-CB 4.43Å; D300-D303 PolarHBondContact O-N 3.24Å; D300-D303 VanDerWaalsContact O-N 3.12Å; D300-I304 WeakPolarHBondContact O-CG1 3.31Å; D300-I304 PolarHBondContact O-N 3.22Å; D300-I304 VanDerWaalsContact O-N 3.14Å
301	P	80.4	Confident	85.6	Confident	87 Å²	87	60.8 Å²	60.8	57%	0.565	33%	0.331	S	S	*	.	H	α-helix	trans	-53.3	-28.3	173.7	-27.2	35.6	0	0	0	114.2	T299 S305	T299-P301 WeakPolarHBondContact O-CD 3.42Å; P301-S305 WeakPolarHBondContact O-CB 2.88Å; P301-S305 PolarHBondContact O-N 3.49Å
302	R	81.6	Confident	85.7	Confident	145 Å²	145	55 Å²	55	55%	0.547	30%	0.304	S	S	.	.	H	α-helix	trans	-65.5	-49.1	176.9	-64.7	174.8	-179.3	-175.2	1.9	111	D300 S305 L306	D300-R302 PolarHBondContact O-N 3.11Å; D300-R302 VanDerWaalsContact O-N 3.09Å; D300-R302 WeakPolarHBondContact OD1-CB 3.19Å; D300-R302 WeakPolarHBondContact OD1-CG 3.26Å; D300-R302 PolarHBondContact OD1-N 3.36Å; R302-S305 WeakPolarHBondContact O-CB 3.27Å; R302-S305 PolarHBondContact O-N 3.01Å; R302-S305 PolarHBondContact O-OG 3.09Å; R302-L306 WeakPolarHBondContact O-CG 3.37Å; R302-L306 PolarHBondContact O-N 3.35Å
303	D	84.5	Confident	85.4	Confident	53 Å²	53	52.5 Å²	52.5	28%	0.283	29%	0.288	S	S	.	.	H	α-helix	trans	-64.2	-46.2	179.5	-66	-14.4	0	0	0	110.8	Y118 S298 D300 S305 L306 A307	Y118-D303 WeakPolarHBondContact CB-O 3.23Å; Y118-D303 WeakPolarHBondContact O-CB 3.33Å; S298-D303 WeakPolarHBondContact OG-CB 3.49Å; S298-D303 PolarHBondContact OG-OD2 3.25Å; D300-D303 HydrophobicContact CB-CB 4.43Å; D300-D303 PolarHBondContact O-N 3.24Å; D300-D303 VanDerWaalsContact O-N 3.12Å; D303-S305 PolarHBondContact O-N 3.32Å; D303-L306 PolarHBondContact O-N 3.33Å; D303-A307 WeakPolarHBondContact O-CB 3.07Å; D303-A307 PolarHBondContact O-N 3.05Å
304	I	84.3	Confident	85.3	Confident	51 Å²	51	50.7 Å²	50.7	26%	0.262	28%	0.277	S	S	.	.	H	α-helix	trans	-56.4	-39.2	176.3	-62.7	170.9	0	0	0	110.6	L124 L128 D300 L308	L124-I304 HydrophobicContact CD2-CG1 4.39Å; L128-I304 HydrophobicContact CD2-CG2 4.38Å; D300-I304 WeakPolarHBondContact O-CG1 3.31Å; D300-I304 PolarHBondContact O-N 3.22Å; D300-I304 VanDerWaalsContact O-N 3.14Å; I304-L308 HydrophobicContact CG2-CD1 4.29Å; I304-L308 WeakPolarHBondContact O-CB 3.06Å; I304-L308 VanDerWaalsContact O-CG 3.32Å; I304-L308 WeakPolarHBondContact O-CG 3.38Å; I304-L308 PolarHBondContact O-N 3.05Å
305	S	78.9	Confident	85.2	Confident	1 Å²	1	45.4 Å²	45.4	1%	0.007	25%	0.253	C	S	.	.	H	α-helix	trans	-66.9	-41.9	177.1	81.2	0	0	0	0	113	P301 R302 D303 A307 L308 Y309 V511	P301-S305 WeakPolarHBondContact O-CB 2.88Å; P301-S305 PolarHBondContact O-N 3.49Å; R302-S305 WeakPolarHBondContact O-CB 3.27Å; R302-S305 PolarHBondContact O-N 3.01Å; R302-S305 PolarHBondContact O-OG 3.09Å; D303-S305 PolarHBondContact O-N 3.32Å; S305-A307 VanDerWaalsContact C-N 3.34Å; S305-L308 WeakPolarHBondContact O-CB 3.43Å; S305-L308 PolarHBondContact O-N 3.37Å; S305-Y309 WeakPolarHBondContact O-CB 3.41Å; S305-Y309 WeakPolarHBondContact O-CD2 3.37Å; S305-Y309 PolarHBondContact O-N 3.18Å; S305-V511 VanDerWaalsContact CB-CG1 3.49Å; S305-V511 WeakPolarHBondContact OG-CG1 3.39Å
306	L	80.8	Confident	85.1	Confident	35 Å²	35	40.9 Å²	40.9	18%	0.183	23%	0.233	C	C	.	.	H	α-helix	trans	-68.5	-35.9	178.5	-67.9	174.4	0	0	0	111.3	Y118 R302 D303 Y309 S310	Y118-L306 HydrophobicContact CD1-CB 3.87Å; Y118-L306 HydrophobicContact CD1-CD1 3.95Å; Y118-L306 HydrophobicContact CD2-CB 3.7Å; Y118-L306 HydrophobicContact CE1-CB 4.08Å; Y118-L306 HydrophobicContact CE1-CD1 3.6Å; Y118-L306 HydrophobicContact CE1-CG 4.48Å; Y118-L306 HydrophobicContact CE2-CB 3.95Å; Y118-L306 HydrophobicContact CG-CB 3.7Å; R302-L306 WeakPolarHBondContact O-CG 3.37Å; R302-L306 PolarHBondContact O-N 3.35Å; D303-L306 PolarHBondContact O-N 3.33Å; L306-Y309 WeakPolarHBondContact O-CB 3.03Å; L306-Y309 PolarHBondContact O-N 2.9Å; L306-S310 PolarHBondContact O-N 3.41Å; L306-S310 PolarHBondContact O-OG 3.23Å
307	A	86.3	Confident	85.1	Confident	0 Å²	0	38 Å²	38	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-62.4	-47.6	171	0	0	0	0	0	111.4	L128 D303 S305 Y309 S310 G311	L128-A307 HydrophobicContact CD1-CB 3.41Å; L128-A307 VanDerWaalsContact CD1-CB 3.41Å; D303-A307 WeakPolarHBondContact O-CB 3.07Å; D303-A307 PolarHBondContact O-N 3.05Å; S305-A307 VanDerWaalsContact C-N 3.34Å; A307-Y309 VanDerWaalsContact C-N 3.3Å; A307-Y309 PolarHBondContact O-N 3.38Å; A307-S310 PolarHBondContact O-N 3.09Å; A307-G311 PolarHBondContact O-N 2.61Å
308	L	85.2	Confident	85	Confident	16 Å²	16	36.2 Å²	36.2	8%	0.084	19%	0.192	C	C	.	.	H	α-helix	trans	-59.8	-40.5	174.8	-78.2	172.6	0	0	0	111.9	L128 F131 I304 S305 G311 L312 F507	L128-L308 HydrophobicContact CD2-CD2 3.66Å; L128-L308 HydrophobicContact CD2-CG 3.96Å; F131-L308 HydrophobicContact CD1-CD2 3.4Å; F131-L308 VanDerWaalsContact CD1-CD2 3.4Å; F131-L308 HydrophobicContact CE1-CD1 4.32Å; F131-L308 HydrophobicContact CE1-CD2 3.7Å; I304-L308 HydrophobicContact CG2-CD1 4.29Å; I304-L308 WeakPolarHBondContact O-CB 3.06Å; I304-L308 VanDerWaalsContact O-CG 3.32Å; I304-L308 WeakPolarHBondContact O-CG 3.38Å; I304-L308 PolarHBondContact O-N 3.05Å; S305-L308 WeakPolarHBondContact O-CB 3.43Å; S305-L308 PolarHBondContact O-N 3.37Å; L308-G311 PolarHBondContact O-N 2.88Å; L308-L312 WeakPolarHBondContact O-CB 3.34Å; L308-L312 WeakPolarHBondContact O-CG 2.96Å; L308-L312 PolarHBondContact O-N 3.14Å; L308-F507 HydrophobicContact CD1-CE1 4.41Å
309	Y	78.4	Confident	85.1	Confident	14 Å²	14	35.6 Å²	35.6	6%	0.055	19%	0.187	C	C	.	.	H	α-helix	trans	-61	-46.4	176	-104.5	-87.7	0	0	0	112.3	S305 L306 A307 F313 Q463 W467 L508 P512	S305-Y309 WeakPolarHBondContact O-CB 3.41Å; S305-Y309 WeakPolarHBondContact O-CD2 3.37Å; S305-Y309 PolarHBondContact O-N 3.18Å; L306-Y309 WeakPolarHBondContact O-CB 3.03Å; L306-Y309 PolarHBondContact O-N 2.9Å; A307-Y309 VanDerWaalsContact C-N 3.3Å; A307-Y309 PolarHBondContact O-N 3.38Å; Y309-F313 WeakPolarHBondContact O-CB 3.5Å; Y309-F313 PolarHBondContact O-N 3.17Å; Y309-Q463 HydrophobicContact CD1-CB 4.23Å; Y309-Q463 HydrophobicContact CE1-CB 3.74Å; Y309-W467 AromaticContact CE1-CD1 3.94Å; Y309-W467 AromaticContact CZ-CD1 3.94Å; Y309-L508 HydrophobicContact CD2-CD2 3.87Å; Y309-L508 HydrophobicContact CE2-CB 4.05Å; Y309-L508 HydrophobicContact CE2-CD2 3.63Å; Y309-L508 HydrophobicContact CE2-CG 4.45Å; Y309-L508 WeakPolarHBondContact CE2-O 3.26Å; Y309-L508 PolarHBondContact OH-O 3.28Å; Y309-P512 HydrophobicContact CD2-CG 4.2Å; Y309-P512 HydrophobicContact CE1-CG 4.39Å; Y309-P512 HydrophobicContact CE2-CG 3.35Å; Y309-P512 VanDerWaalsContact CZ-CG 3.48Å; Y309-P512 WeakPolarHBondContact OH-CG 3.33Å
310	S	81.5	Confident	85.3	Confident	28 Å²	28	30.7 Å²	30.7	20%	0.196	16%	0.155	C	C	.	.	H	α-helix	trans	-61.8	-45.6	176.7	-59.6	0	0	0	0	111.1	S111 L306 A307	S111-S310 WeakPolarHBondContact CB-O 3.42Å; S111-S310 PolarHBondContact OG-O 2.9Å; L306-S310 PolarHBondContact O-N 3.41Å; L306-S310 PolarHBondContact O-OG 3.23Å; A307-S310 PolarHBondContact O-N 3.09Å
311	G	86.4	Confident	85.6	Confident	4 Å²	4	27.7 Å²	27.7	4%	0.041	14%	0.139	C	C	.	.	H	α-helix	trans	-67.1	-45.8	178.1	0	0	0	0	0	112.9	A307 L308 F313 A314 Y315	A307-G311 PolarHBondContact O-N 2.61Å; L308-G311 PolarHBondContact O-N 2.88Å; G311-F313 VanDerWaalsContact C-N 3.27Å; G311-F313 PolarHBondContact O-N 3.26Å; G311-A314 WeakPolarHBondContact O-CB 3.2Å; G311-A314 PolarHBondContact O-N 3.05Å; G311-A314 VanDerWaalsContact O-N 3.08Å; G311-Y315 WeakPolarHBondContact O-CD2 3.26Å; G311-Y315 PolarHBondContact O-N 3.07Å
312	L	87.7	Confident	86.2	Confident	7 Å²	7	23.6 Å²	23.6	4%	0.037	11%	0.112	C	C	.	.	H	α-helix	trans	-69	-24.4	-179.6	-73.2	172.2	0	0	0	113.1	F135 L308 A314 Y315 N316 W467 L508	F135-L312 HydrophobicContact CB-CD2 4.4Å; F135-L312 HydrophobicContact CD1-CD1 4.1Å; F135-L312 HydrophobicContact CD1-CD2 3.81Å; F135-L312 HydrophobicContact CE1-CD1 4.37Å; L308-L312 WeakPolarHBondContact O-CB 3.34Å; L308-L312 WeakPolarHBondContact O-CG 2.96Å; L308-L312 PolarHBondContact O-N 3.14Å; L312-A314 VanDerWaalsContact C-N 3.28Å; L312-A314 PolarHBondContact O-N 2.83Å; L312-Y315 PolarHBondContact O-N 3.31Å; L312-Y315 VanDerWaalsContact O-N 3.17Å; L312-N316 PolarHBondContact O-N 3.43Å; L312-W467 HydrophobicContact CB-CZ2 4.07Å; L312-W467 HydrophobicContact CD1-CH2 4.44Å; L312-W467 HydrophobicContact CD1-CZ2 3.97Å; L312-W467 HydrophobicContact CG-CZ2 4.47Å; L312-L508 HydrophobicContact CD1-CD1 3.5Å; L312-L508 VanDerWaalsContact CD1-CD1 3.5Å; L312-L508 HydrophobicContact CD1-CD2 3.97Å; L312-L508 HydrophobicContact CD1-CG 4.39Å
313	F	82.5	Confident	86.7	Confident	53 Å²	53	16.8 Å²	16.8	23%	0.232	9%	0.086	C	C	.	.	H	α-helix	trans	-58.2	-42.9	168.5	170.8	-104.9	0	0	0	111.2	Y309 G311 Y315 N316 I459	Y309-F313 WeakPolarHBondContact O-CB 3.5Å; Y309-F313 PolarHBondContact O-N 3.17Å; G311-F313 VanDerWaalsContact C-N 3.27Å; G311-F313 PolarHBondContact O-N 3.26Å; F313-Y315 PolarHBondContact O-N 2.93Å; F313-N316 WeakPolarHBondContact O-CB 3.25Å; F313-N316 PolarHBondContact O-N 2.88Å; F313-I459 HydrophobicContact CD2-CG2 4Å; F313-I459 HydrophobicContact CE2-CG2 4.23Å; F313-I459 HydrophobicContact CZ-CD1 4.41Å
314	A	87.6	Confident	87	Confident	1 Å²	1	14.2 Å²	14.2	1%	0.008	7%	0.072	C	C	.	.	H	α-helix	trans	-65.6	-25.8	176.8	0	0	0	0	0	113.2	I103 W129 G311 L312 Y350	I103-A314 WeakPolarHBondContact CG2-O 3.47Å; W129-A314 HydrophobicContact CH2-CB 3.59Å; W129-A314 HydrophobicContact CZ3-CB 3.69Å; G311-A314 WeakPolarHBondContact O-CB 3.2Å; G311-A314 PolarHBondContact O-N 3.05Å; G311-A314 VanDerWaalsContact O-N 3.08Å; L312-A314 VanDerWaalsContact C-N 3.28Å; L312-A314 PolarHBondContact O-N 2.83Å; A314-Y350 HydrophobicContact CB-CE2 4Å; A314-Y350 WeakPolarHBondContact O-CE2 3.38Å; A314-Y350 PolarHBondContact O-OH 2.87Å
315	Y	90.8	Very high	87.4	Confident	5 Å²	5	11.9 Å²	11.9	2%	0.02	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.1	-3.1	176.9	-73.9	-75.2	0	0	0	114.2	W129 G133 A136 G311 L312 F313 G317 V346 Y350	W129-Y315 AromaticContact CE3-CE2 3.68Å; W129-Y315 HydrophobicContact CE3-CE2 3.68Å; W129-Y315 HydrophobicContact CZ3-CE2 4.01Å; W129-Y315 WeakPolarHBondContact O-CE2 3.49Å; W129-Y315 PolarHBondContact O-OH 2.63Å; G133-Y315 VanDerWaalsContact CA-CZ 3.49Å; A136-Y315 HydrophobicContact CB-CD1 4.47Å; A136-Y315 HydrophobicContact CB-CG 4.4Å; G311-Y315 WeakPolarHBondContact O-CD2 3.26Å; G311-Y315 PolarHBondContact O-N 3.07Å; L312-Y315 PolarHBondContact O-N 3.31Å; L312-Y315 VanDerWaalsContact O-N 3.17Å; F313-Y315 PolarHBondContact O-N 2.93Å; Y315-G317 PolarHBondContact O-N 3.33Å; Y315-V346 HydrophobicContact CD1-CG1 4.11Å; Y315-V346 HydrophobicContact CE1-CG1 3.95Å; Y315-Y350 HydrophobicContact CD1-CD2 4.08Å; Y315-Y350 HydrophobicContact CD1-CE2 4.22Å; Y315-Y350 AromaticContact CE1-CD2 3.58Å; Y315-Y350 HydrophobicContact CE1-CD2 3.58Å; Y315-Y350 HydrophobicContact CE1-CE2 4.18Å; Y315-Y350 HydrophobicContact CE1-CG 4.43Å; Y315-Y350 HydrophobicContact CE2-CD2 4.16Å; Y315-Y350 AromaticContact CZ-CD2 3.64Å
316	N	85.5	Confident	87.9	Confident	41 Å²	41	13.3 Å²	13.3	22%	0.219	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.8	132.7	180	-166.3	-39.2	0	0	0	110.6	I103 L312 F313 Q463 N466	I103-N316 WeakPolarHBondContact CA-O 3.41Å; L312-N316 PolarHBondContact O-N 3.43Å; F313-N316 WeakPolarHBondContact O-CB 3.25Å; F313-N316 PolarHBondContact O-N 2.88Å; N316-Q463 PolarHBondContact ND2-OE1 3.41Å; N316-N466 PolarHBondContact ND2-ND2 3.12Å
317	G	88.2	Confident	88.4	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.059	C	C	.	.	T	Hydrogen-bonded Turn	trans	128.1	-13	-174.7	0	0	0	0	0	114.3	Y315 N319 Y320	Y315-G317 PolarHBondContact O-N 3.33Å; G317-N319 PolarHBondContact O-N 3.45Å; G317-N319 VanDerWaalsContact O-N 3.12Å; G317-Y320 VanDerWaalsContact O-CB 3.29Å; G317-Y320 WeakPolarHBondContact O-CB 3.35Å; G317-Y320 PolarHBondContact O-N 3.21Å
318	W	91.7	Very high	88.7	Confident	10 Å²	10	11.7 Å²	11.7	4%	0.038	6%	0.059	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.5	-25.4	-176.2	57.9	-100.7	0	0	0	114.5	I103 A136 G139 A140 Y143 V470 F501	I103-W318 HydrophobicContact CD1-CB 4.2Å; A136-W318 HydrophobicContact CB-CG 4.34Å; G139-W318 WeakPolarHBondContact O-CZ3 3.29Å; A140-W318 VanDerWaalsContact CA-CE3 3.43Å; A140-W318 HydrophobicContact CB-CB 4.31Å; A140-W318 HydrophobicContact CB-CD2 4.32Å; A140-W318 HydrophobicContact CB-CE3 3.61Å; A140-W318 HydrophobicContact CB-CZ3 4.31Å; Y143-W318 HydrophobicContact CD1-CH2 4.45Å; Y143-W318 AromaticContact CD1-CZ3 3.9Å; Y143-W318 HydrophobicContact CD1-CZ3 3.9Å; Y143-W318 AromaticContact CD2-CH2 3.73Å; Y143-W318 HydrophobicContact CD2-CH2 3.73Å; Y143-W318 AromaticContact CD2-CZ3 3.55Å; Y143-W318 HydrophobicContact CD2-CZ3 3.55Å; Y143-W318 HydrophobicContact CE1-CH2 4.31Å; Y143-W318 HydrophobicContact CE1-CZ3 4.18Å; Y143-W318 AromaticContact CE2-CH2 3.57Å; Y143-W318 HydrophobicContact CE2-CH2 3.57Å; Y143-W318 AromaticContact CE2-CZ3 3.87Å; Y143-W318 HydrophobicContact CE2-CZ3 3.87Å; Y143-W318 HydrophobicContact CG-CH2 4.16Å; Y143-W318 AromaticContact CG-CZ3 3.56Å; Y143-W318 HydrophobicContact CG-CZ3 3.56Å; Y143-W318 AromaticContact CZ-CH2 3.87Å; W318-V470 HydrophobicContact CH2-CG1 4.15Å; W318-V470 HydrophobicContact CZ2-CG1 4.04Å; W318-V470 HydrophobicContact CZ2-CG2 4.35Å; W318-F501 HydrophobicContact CH2-CE1 4.41Å; W318-F501 HydrophobicContact CH2-CZ 4.12Å; W318-F501 AromaticContact CZ2-CZ 3.96Å; W318-F501 HydrophobicContact CZ2-CZ 3.96Å
319	N	90.9	Very high	89.1	Confident	7 Å²	7	14.5 Å²	14.5	4%	0.037	7%	0.071	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.5	4.9	177.6	59.3	-21.8	0	0	0	114.3	Y143 D156 G317 L321 N322 F323	Y143-N319 HydrophobicContact CD1-CB 3.59Å; Y143-N319 HydrophobicContact CE1-CB 3.55Å; Y143-N319 HydrophobicContact CG-CB 4.47Å; D156-N319 PolarHBondContact OD1-ND2 3.43Å; G317-N319 PolarHBondContact O-N 3.45Å; G317-N319 VanDerWaalsContact O-N 3.12Å; N319-L321 PolarHBondContact O-N 3.49Å; N319-N322 VanDerWaalsContact O-CB 3.26Å; N319-N322 WeakPolarHBondContact O-CB 3.4Å; N319-N322 PolarHBondContact O-N 2.64Å; N319-N322 VanDerWaalsContact O-N 3.11Å; N319-N322 PolarHBondContact O-OD1 2.85Å; N319-F323 WeakPolarHBondContact O-CD2 3.36Å
320	Y	90.7	Very high	89.8	Confident	24 Å²	24	18.9 Å²	18.9	9%	0.094	10%	0.096	C	C	.	.	H	α-helix	trans	-67.1	-35.2	-168.4	-88.7	-143.7	0	0	0	113.5	C102 G317 N322 F323 V403 T406	C102-Y320 HydrophobicContact CB-CD1 3.66Å; C102-Y320 HydrophobicContact CB-CE1 4.05Å; C102-Y320 HydrophobicContact CB-CG 4.26Å; C102-Y320 WeakPolarHBondContact SG-CD1 3.08Å; G317-Y320 VanDerWaalsContact O-CB 3.29Å; G317-Y320 WeakPolarHBondContact O-CB 3.35Å; G317-Y320 PolarHBondContact O-N 3.21Å; Y320-N322 PolarHBondContact O-N 3.42Å; Y320-F323 WeakPolarHBondContact O-CB 3.38Å; Y320-F323 PolarHBondContact O-N 3.33Å; Y320-V403 HydrophobicContact CE1-CG2 3.86Å; Y320-T406 HydrophobicContact CD1-CG2 3.98Å; Y320-T406 HydrophobicContact CG-CG2 4.24Å; Y320-T406 WeakPolarHBondContact O-CG2 3.09Å
321	L	93.8	Very high	90.3	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-63.4	-26.5	177	-167.4	60.4	0	0	0	112.4	I99 N319 F323 I324 V325 L328 L335 A338	I99-L321 HydrophobicContact CD1-CB 3.73Å; I99-L321 HydrophobicContact CD1-CD2 3.8Å; I99-L321 HydrophobicContact CD1-CG 4.41Å; I99-L321 HydrophobicContact CG1-CB 3.69Å; I99-L321 HydrophobicContact CG1-CD2 4.34Å; N319-L321 PolarHBondContact O-N 3.49Å; L321-F323 PolarHBondContact O-N 2.83Å; L321-I324 HydrophobicContact CD1-CD1 4.04Å; L321-I324 HydrophobicContact CD1-CG1 4Å; L321-I324 CarbonylContact O-C 3.57Å; L321-I324 WeakPolarHBondContact O-CG1 3.35Å; L321-I324 PolarHBondContact O-N 2.83Å; L321-V325 PolarHBondContact O-N 2.87Å; L321-L328 HydrophobicContact CD1-CD1 4.32Å; L321-L328 HydrophobicContact CD2-CD1 4.47Å; L321-L328 HydrophobicContact CD2-CD2 4.07Å; L321-L328 HydrophobicContact CG-CD2 4.26Å; L321-L335 HydrophobicContact CB-CD1 4.1Å; L321-L335 HydrophobicContact CD2-CD1 3.89Å; L321-L335 HydrophobicContact CG-CD1 3.88Å; L321-A338 HydrophobicContact CD2-CB 3.45Å; L321-A338 VanDerWaalsContact CD2-CB 3.45Å
322	N	93.6	Very high	90.6	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-66	-24.9	175.6	-64.2	90.1	0	0	0	113	Y143 G155 Y159 N319 Y320 I324	Y143-N322 HydrophobicContact CD1-CB 4.41Å; Y143-N322 PolarHBondContact O-ND2 2.95Å; G155-N322 PolarHBondContact N-O 3.32Å; Y159-N322 WeakPolarHBondContact OH-CB 3.5Å; Y159-N322 PolarHBondContact OH-ND2 3.14Å; N319-N322 VanDerWaalsContact O-CB 3.26Å; N319-N322 WeakPolarHBondContact O-CB 3.4Å; N319-N322 PolarHBondContact O-N 2.64Å; N319-N322 VanDerWaalsContact O-N 3.11Å; N319-N322 PolarHBondContact O-OD1 2.85Å; Y320-N322 PolarHBondContact O-N 3.42Å; N322-I324 VanDerWaalsContact C-N 3.28Å; N322-I324 PolarHBondContact O-N 3.4Å
323	F	91.1	Very high	90.8	Very high	2 Å²	2	29.3 Å²	29.3	1%	0.009	13%	0.132	C	C	.	.	H	α-helix	trans	-73.7	-22.1	177.7	-70.3	-91.8	0	0	0	113	S153 G154 D156 R204 N319 Y320 L321 T406 L410	S153-F323 WeakPolarHBondContact CA-O 3.47Å; S153-F323 WeakPolarHBondContact CB-O 3.4Å; G154-F323 PolarHBondContact N-O 3.47Å; G154-F323 WeakPolarHBondContact O-CD1 3.31Å; G154-F323 WeakPolarHBondContact O-CE1 3.47Å; D156-F323 HydrophobicContact CB-CZ 4.49Å; R204-F323 VanDerWaalsContact NH2-CD1 3.34Å; N319-F323 WeakPolarHBondContact O-CD2 3.36Å; Y320-F323 WeakPolarHBondContact O-CB 3.38Å; Y320-F323 PolarHBondContact O-N 3.33Å; L321-F323 PolarHBondContact O-N 2.83Å; F323-T406 HydrophobicContact CB-CG2 4.43Å; F323-L410 HydrophobicContact CD1-CB 4.07Å; F323-L410 HydrophobicContact CD1-CD1 4.4Å; F323-L410 HydrophobicContact CE1-CB 4.44Å; F323-L410 HydrophobicContact CE1-CD1 4.2Å; F323-L410 HydrophobicContact CE1-CD2 4.44Å
324	I	91.4	Very high	91.5	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	13%	0.125	C	C	.	.	T	Hydrogen-bonded Turn	trans	-120.8	25	-175.7	61.2	-179.6	0	0	0	111.8	I90 I98 L321 N322 E326 E327 L328 L405 T406 R409	I90-I324 HydrophobicContact CD1-CD1 3.7Å; I90-I324 HydrophobicContact CD1-CG1 4.28Å; I98-I324 HydrophobicContact CD1-CD1 3.74Å; I98-I324 HydrophobicContact CG2-CD1 4.11Å; L321-I324 HydrophobicContact CD1-CD1 4.04Å; L321-I324 HydrophobicContact CD1-CG1 4Å; L321-I324 CarbonylContact O-C 3.57Å; L321-I324 WeakPolarHBondContact O-CG1 3.35Å; L321-I324 PolarHBondContact O-N 2.83Å; N322-I324 VanDerWaalsContact C-N 3.28Å; N322-I324 PolarHBondContact O-N 3.4Å; I324-E326 PolarHBondContact O-N 3.21Å; I324-E326 VanDerWaalsContact O-N 3.17Å; I324-E327 PolarHBondContact O-N 3.21Å; I324-L328 PolarHBondContact O-N 3.47Å; I324-L405 HydrophobicContact CD1-CD2 3.96Å; I324-T406 HydrophobicContact CD1-CG2 4.36Å; I324-T406 HydrophobicContact CG2-CG2 4.16Å; I324-R409 HydrophobicContact CG2-CB 3.99Å; I324-R409 HydrophobicContact CG2-CG 3.88Å
325	V	92.5	Very high	91.8	Very high	1 Å²	1	27.5 Å²	27.5	1%	0.006	12%	0.124	C	C	.	.	G	3₁₀ helix	trans	-60.8	-26.2	-176.7	70.5	0	0	0	0	113.3	K152 L321 E327 L328 P331 L335	K152-V325 VanDerWaalsContact O-CG1 3.32Å; K152-V325 WeakPolarHBondContact O-CG1 3.42Å; L321-V325 PolarHBondContact O-N 2.87Å; V325-E327 VanDerWaalsContact C-N 3.26Å; V325-E327 PolarHBondContact O-N 2.84Å; V325-L328 PolarHBondContact O-N 2.83Å; V325-P331 HydrophobicContact CG2-CB 3.8Å; V325-L335 HydrophobicContact CG2-CD2 4.06Å
326	E	90.1	Very high	92	Very high	31 Å²	31	28.2 Å²	28.2	15%	0.145	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-66.1	-27.8	175.3	-71.8	-179.4	-164.6	0	0	112.7	R88 R151 K152 S153 I324 R416	R88-E326 VanDerWaalsContact CG-O 3.23Å; R88-E326 WeakPolarHBondContact CG-O 3.42Å; R151-E326 WeakPolarHBondContact O-CG 3.49Å; K152-E326 WeakPolarHBondContact CA-OE1 3.2Å; S153-E326 PolarHBondContact N-OE1 2.81Å; S153-E326 WeakPolarHBondContact OG-CB 3.46Å; S153-E326 WeakPolarHBondContact OG-CG 3.42Å; I324-E326 PolarHBondContact O-N 3.21Å; I324-E326 VanDerWaalsContact O-N 3.17Å; E326-R416 IonicContact OE1-NH1 3.24Å; E326-R416 PolarHBondContact OE1-NH1 3.46Å; E326-R416 IonicContact OE2-NH1 2.79Å; E326-R416 PolarHBondContact OE2-NH1 2.82Å
327	E	90.4	Very high	92.5	Very high	2 Å²	2	29.5 Å²	29.5	1%	0.009	14%	0.136	C	C	.	.	G	3₁₀ helix	trans	-90.3	-9.4	179.8	-68.5	173.9	-140.4	0	0	112.5	L86 Q87 R88 S89 I90 I324 V325 R409	L86-E327 HydrophobicContact CB-CG 3.78Å; L86-E327 HydrophobicContact CD1-CG 4.41Å; Q87-E327 WeakPolarHBondContact O-CA 3.29Å; R88-E327 CarbonylContact C-O 3.19Å; R88-E327 VanDerWaalsContact CA-O 3.25Å; R88-E327 WeakPolarHBondContact CA-O 3.47Å; S89-E327 PolarHBondContact N-O 3.38Å; S89-E327 VanDerWaalsContact N-O 3.09Å; I90-E327 WeakPolarHBondContact CB-O 3.37Å; I90-E327 HydrophobicContact CD1-CB 3.76Å; I90-E327 HydrophobicContact CG1-CB 4.1Å; I90-E327 PolarHBondContact N-O 3.46Å; I324-E327 PolarHBondContact O-N 3.21Å; V325-E327 VanDerWaalsContact C-N 3.26Å; V325-E327 PolarHBondContact O-N 2.84Å; E327-R409 IonicContact OE1-CZ 2.98Å; E327-R409 IonicContact OE1-NE 3.98Å; E327-R409 PolarHBondContact OE1-NE 3.38Å; E327-R409 IonicContact OE1-NH2 3.2Å; E327-R409 PolarHBondContact OE1-NH2 2.65Å; E327-R409 IonicContact OE2-CZ 2.95Å; E327-R409 IonicContact OE2-NE 2.71Å; E327-R409 IonicContact OE2-NH2 2.86Å; E327-R409 PolarHBondContact OE2-NH2 3.39Å
328	L	93.7	Very high	92.9	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	14%	0.136	C	C	.	.	B	Isolated β-bridge	trans	-79	129.5	178.9	-172.8	66.2	0	0	0	111.2	I90 L321 I324 V325 P331 N334 L335	I90-L328 HydrophobicContact CB-CD1 4.35Å; I90-L328 HydrophobicContact CG2-CD1 3.86Å; L321-L328 HydrophobicContact CD1-CD1 4.32Å; L321-L328 HydrophobicContact CD2-CD1 4.47Å; L321-L328 HydrophobicContact CD2-CD2 4.07Å; L321-L328 HydrophobicContact CG-CD2 4.26Å; I324-L328 PolarHBondContact O-N 3.47Å; V325-L328 PolarHBondContact O-N 2.83Å; L328-P331 HydrophobicContact CD2-CB 4.2Å; L328-P331 WeakPolarHBondContact O-CD 3.38Å; L328-N334 HydrophobicContact CD1-CB 4.31Å; L328-N334 HydrophobicContact CD2-CB 4.26Å; L328-N334 HydrophobicContact CG-CB 4.28Å; L328-L335 HydrophobicContact CD2-CB 3.67Å; L328-L335 HydrophobicContact CD2-CD1 4.43Å
329	Q	93.1	Very high	93.1	Very high	75 Å²	75	29.3 Å²	29.3	35%	0.35	14%	0.136	S	C	.	.	S	Bend	trans	-69	138.3	171	-67.4	177.4	2.2	0	0	110.1	R88 I90 N334	R88-Q329 HydrophobicContact CB-CG 4.24Å; R88-Q329 VanDerWaalsContact O-CG 3.29Å; R88-Q329 WeakPolarHBondContact O-CG 3.43Å; R88-Q329 PolarHBondContact O-NE2 3.42Å; I90-Q329 WeakPolarHBondContact O-CB 2.93Å; I90-Q329 WeakPolarHBondContact O-CG 3.45Å; I90-Q329 PolarHBondContact O-N 3.05Å; Q329-N334 WeakPolarHBondContact O-CB 3.43Å; Q329-N334 PolarHBondContact O-ND2 2.88Å
330	N	92.6	Very high	93.2	Very high	106 Å²	106	31.5 Å²	31.5	57%	0.567	16%	0.155	S	C	*	.	S	Bend	trans	43.3	57	178.3	-64.9	-21.6	0	0	0	113.7	K332 R333 N334	N330-K332 PolarHBondContact O-N 3.49Å; N330-R333 PolarHBondContact O-N 3.21Å; N330-N334 PolarHBondContact O-N 2.98Å
331	P	92.1	Very high	93.5	Very high	5 Å²	5	34.1 Å²	34.1	3%	0.032	17%	0.169	C	C	.	.	H	α-helix	trans	-60.4	-27.2	-170.4	24.8	-34	0	0	0	112.6	V325 L328 R333 L335 P336	V325-P331 HydrophobicContact CG2-CB 3.8Å; L328-P331 HydrophobicContact CD2-CB 4.2Å; L328-P331 WeakPolarHBondContact O-CD 3.38Å; P331-R333 PolarHBondContact O-N 3.46Å; P331-L335 WeakPolarHBondContact O-CB 3.32Å; P331-L335 PolarHBondContact O-N 3.44Å; P331-L335 VanDerWaalsContact O-N 3.17Å; P331-P336 WeakPolarHBondContact O-CD 3.41Å
332	K	91.7	Very high	93.7	Very high	79 Å²	79	34.1 Å²	34.1	34%	0.343	17%	0.169	S	C	.	.	H	α-helix	trans	-54.1	-37.8	173.5	-71.5	-173.5	169.1	-177	0	113.1	N330 V490	N330-K332 PolarHBondContact O-N 3.49Å; K332-V490 HydrophobicContact CB-CG1 4.4Å; K332-V490 HydrophobicContact CB-CG2 3.98Å; K332-V490 HydrophobicContact CD-CG2 3.68Å; K332-V490 HydrophobicContact CG-CG2 3.73Å
333	R	93.7	Very high	93.8	Very high	174 Å²	174	34.4 Å²	34.4	66%	0.657	17%	0.171	S	C	*	.	H	α-helix	trans	-101.6	-45.4	-179.3	176.5	-178.1	173.8	-166	-1.1	111.8	N330 P331 P336 L337	N330-R333 PolarHBondContact O-N 3.21Å; P331-R333 PolarHBondContact O-N 3.46Å; R333-P336 WeakPolarHBondContact O-CD 3.22Å; R333-L337 HydrophobicContact CG-CD1 3.73Å; R333-L337 VanDerWaalsContact O-CG 3.28Å; R333-L337 WeakPolarHBondContact O-CG 3.27Å; R333-L337 PolarHBondContact O-N 3.26Å
334	N	96	Very high	94	Very high	15 Å²	15	38.5 Å²	38.5	8%	0.08	20%	0.197	C	C	.	.	H	α-helix	trans	-79.1	-32.6	-168	-70.9	-7.9	0	0	0	113	L92 L328 Q329 N330 A338	L92-N334 HydrophobicContact CB-CB 4.31Å; L92-N334 HydrophobicContact CD1-CB 4.12Å; L92-N334 WeakPolarHBondContact CD1-O 3.15Å; L328-N334 HydrophobicContact CD1-CB 4.31Å; L328-N334 HydrophobicContact CD2-CB 4.26Å; L328-N334 HydrophobicContact CG-CB 4.28Å; Q329-N334 WeakPolarHBondContact O-CB 3.43Å; Q329-N334 PolarHBondContact O-ND2 2.88Å; N330-N334 PolarHBondContact O-N 2.98Å; N334-A338 WeakPolarHBondContact O-CB 3.43Å; N334-A338 PolarHBondContact O-N 3.27Å
335	L	94.7	Very high	94.3	Very high	0 Å²	0	41 Å²	41	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-63.7	-50.3	178.8	173.7	69.2	0	0	0	111.4	T148 L321 V325 L328 P331 L337 A338 I339	T148-L335 HydrophobicContact CG2-CD2 4.42Å; L321-L335 HydrophobicContact CB-CD1 4.1Å; L321-L335 HydrophobicContact CD2-CD1 3.89Å; L321-L335 HydrophobicContact CG-CD1 3.88Å; V325-L335 HydrophobicContact CG2-CD2 4.06Å; L328-L335 HydrophobicContact CD2-CB 3.67Å; L328-L335 HydrophobicContact CD2-CD1 4.43Å; P331-L335 WeakPolarHBondContact O-CB 3.32Å; P331-L335 PolarHBondContact O-N 3.44Å; P331-L335 VanDerWaalsContact O-N 3.17Å; L335-L337 PolarHBondContact O-N 2.93Å; L335-A338 PolarHBondContact O-N 3.46Å; L335-I339 HydrophobicContact CD1-CD1 3.8Å; L335-I339 HydrophobicContact CD1-CG1 4.35Å; L335-I339 HydrophobicContact CG-CD1 4.01Å; L335-I339 WeakPolarHBondContact O-CB 3.48Å; L335-I339 WeakPolarHBondContact O-CG1 3.45Å; L335-I339 PolarHBondContact O-N 2.97Å
336	P	95.1	Very high	94.5	Very high	20 Å²	20	41 Å²	41	13%	0.13	21%	0.212	C	C	.	.	H	α-helix	trans	-63.9	-41.6	178.8	-22.7	34.7	0	0	0	113.5	T148 P331 R333 I339 A340 I491	T148-P336 HydrophobicContact CG2-CG 3.86Å; P331-P336 WeakPolarHBondContact O-CD 3.41Å; R333-P336 WeakPolarHBondContact O-CD 3.22Å; P336-I339 PolarHBondContact O-N 2.91Å; P336-A340 WeakPolarHBondContact O-CB 3.49Å; P336-A340 PolarHBondContact O-N 3.29Å; P336-I491 HydrophobicContact CB-CD1 3.22Å; P336-I491 HydrophobicContact CG-CD1 3.16Å; P336-I491 HydrophobicContact CG-CG1 4.21Å
337	L	96	Very high	94.8	Very high	68 Å²	68	40.7 Å²	40.7	36%	0.356	21%	0.212	S	C	.	.	H	α-helix	trans	-64.2	-45.4	178	-71.3	175.7	0	0	0	111.4	L92 R333 L335 I339 A340 I341	L92-L337 HydrophobicContact CD1-CB 3.85Å; L92-L337 HydrophobicContact CD2-CD1 4.32Å; R333-L337 HydrophobicContact CG-CD1 3.73Å; R333-L337 VanDerWaalsContact O-CG 3.28Å; R333-L337 WeakPolarHBondContact O-CG 3.27Å; R333-L337 PolarHBondContact O-N 3.26Å; L335-L337 PolarHBondContact O-N 2.93Å; L337-I339 VanDerWaalsContact C-N 3.32Å; L337-I339 PolarHBondContact O-N 2.91Å; L337-A340 PolarHBondContact O-N 3.27Å; L337-I341 WeakPolarHBondContact O-CB 3.38Å; L337-I341 WeakPolarHBondContact O-CD1 3.48Å; L337-I341 VanDerWaalsContact O-CG1 3.22Å; L337-I341 WeakPolarHBondContact O-CG1 3.35Å; L337-I341 PolarHBondContact O-N 2.95Å
338	A	96.6	Very high	95.1	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-59.6	-45	177.7	0	0	0	0	0	111.4	L92 I99 L321 N334 L335 S342	L92-A338 HydrophobicContact CD1-CB 3.99Å; I99-A338 HydrophobicContact CD1-CB 4.11Å; L321-A338 HydrophobicContact CD2-CB 3.45Å; L321-A338 VanDerWaalsContact CD2-CB 3.45Å; N334-A338 WeakPolarHBondContact O-CB 3.43Å; N334-A338 PolarHBondContact O-N 3.27Å; L335-A338 PolarHBondContact O-N 3.46Å; A338-S342 WeakPolarHBondContact O-CB 3.39Å; A338-S342 PolarHBondContact O-N 2.93Å; A338-S342 PolarHBondContact O-OG 3.3Å
339	I	94.4	Very high	95.3	Very high	6 Å²	6	45.1 Å²	45.1	3%	0.031	24%	0.239	C	C	.	.	H	α-helix	trans	-59.4	-52.1	176.3	-77	170	0	0	0	111.3	I99 A140 L335 P336 L337 S342 C343	I99-I339 HydrophobicContact CD1-CG1 3.92Å; A140-I339 HydrophobicContact CB-CG2 3.28Å; L335-I339 HydrophobicContact CD1-CD1 3.8Å; L335-I339 HydrophobicContact CD1-CG1 4.35Å; L335-I339 HydrophobicContact CG-CD1 4.01Å; L335-I339 WeakPolarHBondContact O-CB 3.48Å; L335-I339 WeakPolarHBondContact O-CG1 3.45Å; L335-I339 PolarHBondContact O-N 2.97Å; P336-I339 PolarHBondContact O-N 2.91Å; L337-I339 VanDerWaalsContact C-N 3.32Å; L337-I339 PolarHBondContact O-N 2.91Å; I339-S342 PolarHBondContact O-N 2.96Å; I339-C343 WeakPolarHBondContact O-CB 3.13Å; I339-C343 PolarHBondContact O-N 2.96Å; I339-C343 PolarHBondContact O-SG 3.48Å
340	A	94.7	Very high	95.5	Very high	53 Å²	53	41.6 Å²	41.6	44%	0.438	22%	0.222	S	C	.	.	H	α-helix	trans	-63.9	-46.2	-175.7	0	0	0	0	0	112.1	P336 L337 T344	P336-A340 WeakPolarHBondContact O-CB 3.49Å; P336-A340 PolarHBondContact O-N 3.29Å; L337-A340 PolarHBondContact O-N 3.27Å; A340-T344 WeakPolarHBondContact O-CB 3.44Å; A340-T344 PolarHBondContact O-N 3.25Å; A340-T344 VanDerWaalsContact O-N 3.17Å; A340-T344 PolarHBondContact O-OG1 3.5Å
341	I	96.9	Very high	95.7	Very high	79 Å²	79	37.6 Å²	37.6	41%	0.405	20%	0.201	S	C	.	.	H	α-helix	trans	-61.9	-49	177.9	-66.8	166.5	0	0	0	109.7	L337 T344 V345	L337-I341 WeakPolarHBondContact O-CB 3.38Å; L337-I341 WeakPolarHBondContact O-CD1 3.48Å; L337-I341 VanDerWaalsContact O-CG1 3.22Å; L337-I341 WeakPolarHBondContact O-CG1 3.35Å; L337-I341 PolarHBondContact O-N 2.95Å; I341-T344 PolarHBondContact O-N 3.03Å; I341-V345 HydrophobicContact CG2-CG2 4.18Å; I341-V345 WeakPolarHBondContact O-CB 3.29Å; I341-V345 VanDerWaalsContact O-CG2 3.25Å; I341-V345 WeakPolarHBondContact O-CG2 3.4Å; I341-V345 PolarHBondContact O-N 3.44Å
342	S	96.7	Very high	95.9	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-65.8	-45.2	-174.4	-55.9	0	0	0	0	112.5	C96 A338 I339 T344 V345 V346	C96-S342 WeakPolarHBondContact CA-OG 3.41Å; C96-S342 PolarHBondContact O-OG 3.17Å; A338-S342 WeakPolarHBondContact O-CB 3.39Å; A338-S342 PolarHBondContact O-N 2.93Å; A338-S342 PolarHBondContact O-OG 3.3Å; I339-S342 PolarHBondContact O-N 2.96Å; S342-T344 VanDerWaalsContact C-N 3.32Å; S342-T344 PolarHBondContact O-N 3.26Å; S342-V345 PolarHBondContact O-N 2.86Å; S342-V346 WeakPolarHBondContact O-CB 3.36Å; S342-V346 VanDerWaalsContact O-CG2 3.28Å; S342-V346 WeakPolarHBondContact O-CG2 3.4Å; S342-V346 PolarHBondContact O-N 3.43Å
343	C	95.8	Very high	96.2	Very high	6 Å²	6	36.4 Å²	36.4	4%	0.041	20%	0.198	C	C	.	.	H	α-helix	trans	-63.3	-40.4	178.4	-63.3	0	0	0	0	111.3	A137 I339 T347	A137-C343 HydrophobicContact CB-CB 3.99Å; I339-C343 WeakPolarHBondContact O-CB 3.13Å; I339-C343 PolarHBondContact O-N 2.96Å; I339-C343 PolarHBondContact O-SG 3.48Å; C343-T347 VanDerWaalsContact O-CB 3.32Å; C343-T347 WeakPolarHBondContact O-CB 3.42Å; C343-T347 PolarHBondContact O-N 3.34Å; C343-T347 PolarHBondContact O-OG1 2.99Å
344	T	96.5	Very high	96.3	Very high	89 Å²	89	28.1 Å²	28.1	55%	0.546	17%	0.167	S	C	.	.	H	α-helix	trans	-65.4	-50.9	178.3	-54.3	0	0	0	0	111.2	A340 I341 S342 V346 T347 V348	A340-T344 WeakPolarHBondContact O-CB 3.44Å; A340-T344 PolarHBondContact O-N 3.25Å; A340-T344 VanDerWaalsContact O-N 3.17Å; A340-T344 PolarHBondContact O-OG1 3.5Å; I341-T344 PolarHBondContact O-N 3.03Å; S342-T344 VanDerWaalsContact C-N 3.32Å; S342-T344 PolarHBondContact O-N 3.26Å; T344-V346 PolarHBondContact O-N 2.92Å; T344-T347 PolarHBondContact O-N 3.02Å; T344-V348 WeakPolarHBondContact O-CG2 3.33Å; T344-V348 PolarHBondContact O-N 3.36Å
345	V	96.2	Very high	96.2	Very high	53 Å²	53	29.3 Å²	29.3	32%	0.321	17%	0.173	S	C	.	.	H	α-helix	trans	-58.6	-47.9	-179.8	168	0	0	0	0	110.9	I341 S342 V348 I349	I341-V345 HydrophobicContact CG2-CG2 4.18Å; I341-V345 WeakPolarHBondContact O-CB 3.29Å; I341-V345 VanDerWaalsContact O-CG2 3.25Å; I341-V345 WeakPolarHBondContact O-CG2 3.4Å; I341-V345 PolarHBondContact O-N 3.44Å; S342-V345 PolarHBondContact O-N 2.86Å; V345-V348 PolarHBondContact O-N 2.98Å; V345-I349 HydrophobicContact CG1-CD1 3.61Å; V345-I349 HydrophobicContact CG1-CG1 4.41Å; V345-I349 WeakPolarHBondContact O-CB 3.46Å; V345-I349 VanDerWaalsContact O-CG1 3.26Å; V345-I349 WeakPolarHBondContact O-CG1 3.49Å; V345-I349 PolarHBondContact O-N 2.97Å
346	V	96.7	Very high	96.3	Very high	1 Å²	1	29.3 Å²	29.3	1%	0.006	17%	0.173	C	C	.	.	H	α-helix	trans	-65.8	-43.5	-179.4	175.1	0	0	0	0	111.5	V100 I103 I104 Y315 S342 T344 V348 I349 Y350	V100-V346 HydrophobicContact CB-CG2 4.33Å; V100-V346 HydrophobicContact CG1-CG2 3.96Å; V100-V346 HydrophobicContact CG2-CG2 4.14Å; I103-V346 HydrophobicContact CB-CG1 4.49Å; I103-V346 HydrophobicContact CB-CG2 4.43Å; I103-V346 HydrophobicContact CD1-CG2 4.33Å; I103-V346 HydrophobicContact CG2-CG1 3.7Å; I103-V346 HydrophobicContact CG2-CG2 4.48Å; I104-V346 HydrophobicContact CD1-CG2 4.39Å; I104-V346 HydrophobicContact CG1-CG2 4.25Å; Y315-V346 HydrophobicContact CD1-CG1 4.11Å; Y315-V346 HydrophobicContact CE1-CG1 3.95Å; S342-V346 WeakPolarHBondContact O-CB 3.36Å; S342-V346 VanDerWaalsContact O-CG2 3.28Å; S342-V346 WeakPolarHBondContact O-CG2 3.4Å; S342-V346 PolarHBondContact O-N 3.43Å; T344-V346 PolarHBondContact O-N 2.92Å; V346-V348 VanDerWaalsContact C-N 3.33Å; V346-V348 PolarHBondContact O-N 3.24Å; V346-I349 PolarHBondContact O-N 3.28Å; V346-Y350 HydrophobicContact CG1-CD1 3.96Å; V346-Y350 HydrophobicContact CG1-CD2 3.66Å; V346-Y350 HydrophobicContact CG1-CE1 3.85Å; V346-Y350 HydrophobicContact CG1-CE2 3.53Å; V346-Y350 HydrophobicContact CG1-CG 3.9Å; V346-Y350 VanDerWaalsContact O-CB 3.26Å; V346-Y350 WeakPolarHBondContact O-CB 3.46Å; V346-Y350 VanDerWaalsContact O-CG 3.32Å; V346-Y350 PolarHBondContact O-N 3.26Å
347	T	96.6	Very high	96.2	Very high	23 Å²	23	28.3 Å²	28.3	14%	0.141	17%	0.167	C	C	.	.	H	α-helix	trans	-60.1	-44.8	179.5	-56.6	0	0	0	0	111.5	G133 C343 T344 T351	G133-T347 VanDerWaalsContact CA-OG1 3.29Å; G133-T347 WeakPolarHBondContact CA-OG1 3.46Å; C343-T347 VanDerWaalsContact O-CB 3.32Å; C343-T347 WeakPolarHBondContact O-CB 3.42Å; C343-T347 PolarHBondContact O-N 3.34Å; C343-T347 PolarHBondContact O-OG1 2.99Å; T344-T347 PolarHBondContact O-N 3.02Å; T347-T351 WeakPolarHBondContact O-CB 3.44Å; T347-T351 PolarHBondContact O-N 3.31Å; T347-T351 PolarHBondContact O-OG1 3.48Å
348	V	97.6	Very high	96.1	Very high	79 Å²	79	25.1 Å²	25.1	48%	0.479	15%	0.15	S	C	.	.	H	α-helix	trans	-64.1	-50.6	177.2	172.7	0	0	0	0	110.5	T344 V345 V346 Y350 T351 L352	T344-V348 WeakPolarHBondContact O-CG2 3.33Å; T344-V348 PolarHBondContact O-N 3.36Å; V345-V348 PolarHBondContact O-N 2.98Å; V346-V348 VanDerWaalsContact C-N 3.33Å; V346-V348 PolarHBondContact O-N 3.24Å; V348-Y350 VanDerWaalsContact C-N 3.34Å; V348-Y350 PolarHBondContact O-N 3.18Å; V348-T351 PolarHBondContact O-N 3.17Å; V348-L352 HydrophobicContact CG1-CD1 3.73Å; V348-L352 HydrophobicContact CG1-CG 4.34Å; V348-L352 WeakPolarHBondContact O-CB 3.33Å; V348-L352 VanDerWaalsContact O-CG 3.26Å; V348-L352 WeakPolarHBondContact O-CG 3.29Å; V348-L352 PolarHBondContact O-N 3.41Å
349	I	97	Very high	95.9	Very high	17 Å²	17	25.7 Å²	25.7	9%	0.087	15%	0.154	C	C	.	.	H	α-helix	trans	-60.7	-44.5	-179.2	-70.7	174.5	0	0	0	110.9	I268 L271 V345 V346 L352 T353	I268-I349 HydrophobicContact CG1-CD1 4.48Å; I268-I349 HydrophobicContact CG2-CD1 4.07Å; L271-I349 HydrophobicContact CB-CG2 3.65Å; L271-I349 HydrophobicContact CD1-CG2 3.53Å; L271-I349 HydrophobicContact CG-CG2 4.17Å; V345-I349 HydrophobicContact CG1-CD1 3.61Å; V345-I349 HydrophobicContact CG1-CG1 4.41Å; V345-I349 WeakPolarHBondContact O-CB 3.46Å; V345-I349 VanDerWaalsContact O-CG1 3.26Å; V345-I349 WeakPolarHBondContact O-CG1 3.49Å; V345-I349 PolarHBondContact O-N 2.97Å; V346-I349 PolarHBondContact O-N 3.28Å; I349-L352 PolarHBondContact O-N 3.37Å; I349-T353 VanDerWaalsContact O-CB 3.23Å; I349-T353 WeakPolarHBondContact O-CB 3.28Å; I349-T353 PolarHBondContact O-N 2.82Å; I349-T353 PolarHBondContact O-OG1 2.86Å
350	Y	97.4	Very high	95.7	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-65.8	-44.5	-179	-78	6.8	0	0	0	112.1	I103 I104 I108 W129 L271 A314 Y315 V346 V348 T353 N354	I103-Y350 HydrophobicContact CG2-CE2 4.12Å; I103-Y350 PolarHBondContact O-OH 3.25Å; I104-Y350 WeakPolarHBondContact CA-OH 3.48Å; I104-Y350 HydrophobicContact CG1-CE1 3.9Å; I108-Y350 HydrophobicContact CB-CD1 3.94Å; I108-Y350 HydrophobicContact CB-CE1 3.48Å; I108-Y350 VanDerWaalsContact CB-CE1 3.48Å; I108-Y350 HydrophobicContact CB-CE2 4.31Å; I108-Y350 HydrophobicContact CD1-CD1 3.67Å; I108-Y350 HydrophobicContact CD1-CD2 4.14Å; I108-Y350 HydrophobicContact CD1-CE1 4.14Å; I108-Y350 HydrophobicContact CD1-CG 3.64Å; I108-Y350 HydrophobicContact CG1-CD1 3.58Å; I108-Y350 HydrophobicContact CG1-CE1 3.67Å; I108-Y350 HydrophobicContact CG1-CG 4.1Å; I108-Y350 HydrophobicContact CG2-CE1 3.82Å; W129-Y350 HydrophobicContact CE3-CD2 4.06Å; W129-Y350 HydrophobicContact CE3-CG 4.45Å; W129-Y350 AromaticContact CZ3-CD2 3.54Å; W129-Y350 HydrophobicContact CZ3-CD2 3.54Å; W129-Y350 HydrophobicContact CZ3-CE2 4.17Å; W129-Y350 HydrophobicContact CZ3-CG 4.13Å; L271-Y350 HydrophobicContact CD1-CE1 4.48Å; A314-Y350 HydrophobicContact CB-CE2 4Å; A314-Y350 WeakPolarHBondContact O-CE2 3.38Å; A314-Y350 PolarHBondContact O-OH 2.87Å; Y315-Y350 HydrophobicContact CD1-CD2 4.08Å; Y315-Y350 HydrophobicContact CD1-CE2 4.22Å; Y315-Y350 AromaticContact CE1-CD2 3.58Å; Y315-Y350 HydrophobicContact CE1-CD2 3.58Å; Y315-Y350 HydrophobicContact CE1-CE2 4.18Å; Y315-Y350 HydrophobicContact CE1-CG 4.43Å; Y315-Y350 HydrophobicContact CE2-CD2 4.16Å; Y315-Y350 AromaticContact CZ-CD2 3.64Å; V346-Y350 HydrophobicContact CG1-CD1 3.96Å; V346-Y350 HydrophobicContact CG1-CD2 3.66Å; V346-Y350 HydrophobicContact CG1-CE1 3.85Å; V346-Y350 HydrophobicContact CG1-CE2 3.53Å; V346-Y350 HydrophobicContact CG1-CG 3.9Å; V346-Y350 VanDerWaalsContact O-CB 3.26Å; V346-Y350 WeakPolarHBondContact O-CB 3.46Å; V346-Y350 VanDerWaalsContact O-CG 3.32Å; V346-Y350 PolarHBondContact O-N 3.26Å; V348-Y350 VanDerWaalsContact C-N 3.34Å; V348-Y350 PolarHBondContact O-N 3.18Å; Y350-T353 PolarHBondContact O-N 3.19Å; Y350-N354 PolarHBondContact O-N 3.05Å; Y350-N354 PolarHBondContact O-ND2 2.93Å
351	T	96.8	Very high	95.5	Very high	22 Å²	22	24.3 Å²	24.3	14%	0.135	14%	0.141	C	C	.	.	H	α-helix	trans	-60.9	-48.6	177	-54.2	0	0	0	0	110.4	V130 T347 V348 T353 N354 I355	V130-T351 HydrophobicContact CG2-CG2 3.65Å; T347-T351 WeakPolarHBondContact O-CB 3.44Å; T347-T351 PolarHBondContact O-N 3.31Å; T347-T351 PolarHBondContact O-OG1 3.48Å; V348-T351 PolarHBondContact O-N 3.17Å; T351-T353 VanDerWaalsContact C-N 3.33Å; T351-T353 PolarHBondContact O-N 3.19Å; T351-N354 PolarHBondContact O-N 3.12Å; T351-I355 HydrophobicContact CG2-CD1 4.24Å; T351-I355 WeakPolarHBondContact O-CG1 3.31Å; T351-I355 PolarHBondContact O-N 3.4Å
352	L	97.6	Very high	95.1	Very high	60 Å²	60	21.8 Å²	21.8	31%	0.314	13%	0.13	S	C	.	.	H	α-helix	trans	-64.7	-35.9	178	-67.9	177.1	0	0	0	112.7	V275 V348 I349 I355 A356	V275-L352 HydrophobicContact CB-CB 4.45Å; V275-L352 HydrophobicContact CG1-CB 3.81Å; V275-L352 HydrophobicContact CG1-CD1 4.17Å; V275-L352 HydrophobicContact CG2-CB 3.7Å; V348-L352 HydrophobicContact CG1-CD1 3.73Å; V348-L352 HydrophobicContact CG1-CG 4.34Å; V348-L352 WeakPolarHBondContact O-CB 3.33Å; V348-L352 VanDerWaalsContact O-CG 3.26Å; V348-L352 WeakPolarHBondContact O-CG 3.29Å; V348-L352 PolarHBondContact O-N 3.41Å; I349-L352 PolarHBondContact O-N 3.37Å; L352-I355 HydrophobicContact CD2-CD1 4.36Å; L352-I355 PolarHBondContact O-N 2.77Å; L352-A356 WeakPolarHBondContact O-CB 3.46Å; L352-A356 PolarHBondContact O-N 3.12Å
353	T	96.4	Very high	94.7	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-65.8	-41.2	177.3	-59.4	0	0	0	0	110.6	I108 L271 I274 I349 Y350 T351 A356 F357	I108-T353 HydrophobicContact CG1-CG2 4.12Å; L271-T353 HydrophobicContact CD2-CG2 3.98Å; I274-T353 HydrophobicContact CG2-CG2 4.12Å; I349-T353 VanDerWaalsContact O-CB 3.23Å; I349-T353 WeakPolarHBondContact O-CB 3.28Å; I349-T353 PolarHBondContact O-N 2.82Å; I349-T353 PolarHBondContact O-OG1 2.86Å; Y350-T353 PolarHBondContact O-N 3.19Å; T351-T353 VanDerWaalsContact C-N 3.33Å; T351-T353 PolarHBondContact O-N 3.19Å; T353-A356 WeakPolarHBondContact O-CB 3.16Å; T353-A356 PolarHBondContact O-N 3.05Å; T353-F357 HydrophobicContact CG2-CD2 4.17Å; T353-F357 HydrophobicContact CG2-CE1 4.25Å; T353-F357 HydrophobicContact CG2-CE2 3.6Å; T353-F357 HydrophobicContact CG2-CZ 3.64Å; T353-F357 WeakPolarHBondContact O-CG 3.43Å; T353-F357 PolarHBondContact O-N 3.14Å
354	N	95.6	Very high	94.1	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-67.6	-39	175.4	-77.6	-83.3	0	0	0	112.1	I108 P112 L126 W129 Y350 T351 A356 F357 Y358	I108-N354 WeakPolarHBondContact CD1-ND2 3.18Å; P112-N354 WeakPolarHBondContact CB-OD1 3.49Å; P112-N354 WeakPolarHBondContact CG-OD1 3.33Å; L126-N354 HydrophobicContact CD2-CB 3.78Å; W129-N354 VanDerWaalsContact CD2-ND2 3.29Å; W129-N354 PolarHBondContact NE1-ND2 3.3Å; W129-N354 PolarHBondContact NE1-OD1 2.78Å; Y350-N354 PolarHBondContact O-N 3.05Å; Y350-N354 PolarHBondContact O-ND2 2.93Å; T351-N354 PolarHBondContact O-N 3.12Å; N354-A356 VanDerWaalsContact C-N 3.29Å; N354-A356 PolarHBondContact O-N 3.06Å; N354-F357 PolarHBondContact O-N 2.88Å; N354-Y358 WeakPolarHBondContact O-CD2 3.39Å; N354-Y358 PolarHBondContact O-N 3.41Å
355	I	95.5	Very high	93.5	Very high	39 Å²	39	27.6 Å²	27.6	20%	0.2	15%	0.15	C	C	.	.	H	α-helix	trans	-57.9	-45.2	171.1	-68.1	167.1	0	0	0	110.3	L126 L279 F290 T351 L352 F357 Y358 A359	L126-I355 HydrophobicContact CD1-CG1 3.89Å; L126-I355 HydrophobicContact CD2-CG1 3.78Å; L279-I355 HydrophobicContact CD2-CG2 4.31Å; F290-I355 HydrophobicContact CE2-CG2 4.47Å; F290-I355 HydrophobicContact CZ-CG2 4.02Å; T351-I355 HydrophobicContact CG2-CD1 4.24Å; T351-I355 WeakPolarHBondContact O-CG1 3.31Å; T351-I355 PolarHBondContact O-N 3.4Å; L352-I355 HydrophobicContact CD2-CD1 4.36Å; L352-I355 PolarHBondContact O-N 2.77Å; I355-F357 PolarHBondContact O-N 2.85Å; I355-Y358 PolarHBondContact O-N 3.09Å; I355-A359 WeakPolarHBondContact O-CB 3.42Å; I355-A359 PolarHBondContact O-N 3.29Å
356	A	95.3	Very high	92.7	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-62.2	-40.3	176.9	0	0	0	0	0	112.6	I274 L352 T353 N354 A359 F376	I274-A356 HydrophobicContact CG2-CB 4.17Å; L352-A356 WeakPolarHBondContact O-CB 3.46Å; L352-A356 PolarHBondContact O-N 3.12Å; T353-A356 WeakPolarHBondContact O-CB 3.16Å; T353-A356 PolarHBondContact O-N 3.05Å; N354-A356 VanDerWaalsContact C-N 3.29Å; N354-A356 PolarHBondContact O-N 3.06Å; A356-A359 PolarHBondContact O-N 3.47Å; A356-F376 WeakPolarHBondContact O-CE2 3.38Å
357	F	94	Very high	91.8	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-61.9	-47.5	174.3	-68.4	-31.6	0	0	0	111.9	P112 I274 T353 N354 I355 A359 V360 I361 F366 T372 A373 F376	P112-F357 HydrophobicContact CB-CD2 4.39Å; P112-F357 HydrophobicContact CG-CD2 4.08Å; P112-F357 HydrophobicContact CG-CE2 3.99Å; I274-F357 HydrophobicContact CG2-CD1 4.32Å; I274-F357 HydrophobicContact CG2-CE1 3.88Å; T353-F357 HydrophobicContact CG2-CD2 4.17Å; T353-F357 HydrophobicContact CG2-CE1 4.25Å; T353-F357 HydrophobicContact CG2-CE2 3.6Å; T353-F357 HydrophobicContact CG2-CZ 3.64Å; T353-F357 WeakPolarHBondContact O-CG 3.43Å; T353-F357 PolarHBondContact O-N 3.14Å; N354-F357 PolarHBondContact O-N 2.88Å; I355-F357 PolarHBondContact O-N 2.85Å; F357-A359 VanDerWaalsContact C-N 3.3Å; F357-A359 PolarHBondContact O-N 3.44Å; F357-V360 PolarHBondContact O-N 3.4Å; F357-I361 WeakPolarHBondContact O-CB 3.32Å; F357-I361 PolarHBondContact O-N 2.8Å; F357-F366 HydrophobicContact CB-CE2 3.96Å; F357-F366 HydrophobicContact CB-CZ 3.88Å; F357-T372 HydrophobicContact CB-CG2 4.05Å; F357-T372 HydrophobicContact CD1-CG2 4.17Å; F357-T372 HydrophobicContact CD2-CG2 3.64Å; F357-T372 HydrophobicContact CE2-CG2 4.05Å; F357-T372 HydrophobicContact CG-CG2 3.71Å; F357-T372 HydrophobicContact CZ-CG2 4.49Å; F357-A373 HydrophobicContact CE1-CB 4.48Å; F357-A373 HydrophobicContact CZ-CB 4.21Å; F357-F376 HydrophobicContact CD1-CB 3.86Å; F357-F376 AromaticContact CD1-CD2 3.75Å; F357-F376 HydrophobicContact CD1-CD2 3.75Å; F357-F376 HydrophobicContact CD1-CE2 4.48Å; F357-F376 AromaticContact CD1-CG 3.84Å; F357-F376 HydrophobicContact CD1-CG 3.84Å; F357-F376 HydrophobicContact CE1-CB 3.97Å; F357-F376 HydrophobicContact CE1-CD2 4.39Å; F357-F376 HydrophobicContact CE1-CG 4.05Å
358	Y	94	Very high	91.1	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-68.1	-26.8	178.4	-71.8	-60.1	0	0	0	113.8	H116 V122 S125 L126 S289 N354 I355 V360 F366	H116-Y358 VanDerWaalsContact CB-OH 3.3Å; H116-Y358 WeakPolarHBondContact CB-OH 3.43Å; H116-Y358 AromaticContact CE1-CE1 3.98Å; H116-Y358 VanDerWaalsContact CG-OH 3.32Å; H116-Y358 AromaticContact ND1-CE1 3.62Å; H116-Y358 AromaticContact ND1-CZ 3.64Å; H116-Y358 PolarHBondContact ND1-OH 3.48Å; V122-Y358 HydrophobicContact CB-CE1 4.49Å; V122-Y358 HydrophobicContact CG1-CD1 4.07Å; V122-Y358 HydrophobicContact CG1-CD2 3.68Å; V122-Y358 HydrophobicContact CG1-CE1 4.35Å; V122-Y358 HydrophobicContact CG1-CE2 3.98Å; V122-Y358 HydrophobicContact CG1-CG 3.71Å; V122-Y358 HydrophobicContact CG2-CD1 3.81Å; V122-Y358 HydrophobicContact CG2-CE1 3.82Å; V122-Y358 HydrophobicContact CG2-CG 4.32Å; S125-Y358 WeakPolarHBondContact CB-OH 3.4Å; S125-Y358 PolarHBondContact OG-OH 2.88Å; L126-Y358 HydrophobicContact CD2-CD2 4.24Å; L126-Y358 HydrophobicContact CD2-CE2 4.28Å; L126-Y358 HydrophobicContact CG-CE2 4.46Å; S289-Y358 VanDerWaalsContact CB-O 3.25Å; S289-Y358 WeakPolarHBondContact CB-O 3.45Å; S289-Y358 PolarHBondContact OG-O 2.92Å; S289-Y358 VanDerWaalsContact OG-O 3.05Å; N354-Y358 WeakPolarHBondContact O-CD2 3.39Å; N354-Y358 PolarHBondContact O-N 3.41Å; I355-Y358 PolarHBondContact O-N 3.09Å; Y358-V360 PolarHBondContact O-N 3.42Å; Y358-F366 HydrophobicContact CD1-CD2 4.14Å; Y358-F366 AromaticContact CD1-CE2 3.88Å; Y358-F366 HydrophobicContact CD1-CE2 3.88Å; Y358-F366 HydrophobicContact CD1-CZ 4.36Å; Y358-F366 HydrophobicContact CE1-CD1 4.43Å; Y358-F366 AromaticContact CE1-CD2 3.96Å; Y358-F366 HydrophobicContact CE1-CD2 3.96Å; Y358-F366 HydrophobicContact CE1-CE1 4.3Å; Y358-F366 AromaticContact CE1-CE2 3.84Å; Y358-F366 HydrophobicContact CE1-CE2 3.84Å; Y358-F366 HydrophobicContact CE1-CG 4.26Å; Y358-F366 HydrophobicContact CE1-CZ 4.01Å
359	A	92.5	Very high	89.9	Confident	12 Å²	12	31.7 Å²	31.7	10%	0.099	17%	0.166	C	C	.	.	H	α-helix	trans	-63.4	-26	174.7	0	0	0	0	0	113.1	G278 L282 S287 F290 I355 A356 F357	G278-A359 WeakPolarHBondContact O-CB 3.46Å; L282-A359 HydrophobicContact CB-CB 3.99Å; L282-A359 HydrophobicContact CD1-CB 4.4Å; S287-A359 VanDerWaalsContact CB-O 3.31Å; S287-A359 WeakPolarHBondContact CB-O 3.38Å; F290-A359 HydrophobicContact CE2-CB 4.34Å; I355-A359 WeakPolarHBondContact O-CB 3.42Å; I355-A359 PolarHBondContact O-N 3.29Å; A356-A359 PolarHBondContact O-N 3.47Å; F357-A359 VanDerWaalsContact C-N 3.3Å; F357-A359 PolarHBondContact O-N 3.44Å
360	V	90.6	Very high	88.5	Confident	27 Å²	27	35.6 Å²	35.6	16%	0.164	19%	0.188	C	C	.	.	H	α-helix	trans	-112	-35.6	-175	171.1	0	0	0	0	112.4	M281 F357 Y358 F376 K379 V380	M281-V360 HydrophobicContact CB-CG2 4.12Å; M281-V360 HydrophobicContact CG-CG2 4.12Å; F357-V360 PolarHBondContact O-N 3.4Å; Y358-V360 PolarHBondContact O-N 3.42Å; V360-F376 HydrophobicContact CB-CD2 3.74Å; V360-F376 HydrophobicContact CB-CE2 3.75Å; V360-F376 HydrophobicContact CG1-CD2 3.95Å; V360-F376 HydrophobicContact CG1-CE2 4.23Å; V360-F376 HydrophobicContact CG2-CD2 3.97Å; V360-F376 HydrophobicContact CG2-CE2 3.42Å; V360-F376 VanDerWaalsContact CG2-CE2 3.42Å; V360-F376 HydrophobicContact CG2-CZ 4.25Å; V360-K379 HydrophobicContact CG1-CB 3.86Å; V360-K379 HydrophobicContact CG1-CD 4.23Å; V360-V380 HydrophobicContact CB-CG2 4.26Å; V360-V380 HydrophobicContact CG1-CG2 3.41Å; V360-V380 VanDerWaalsContact CG1-CG2 3.41Å; V360-V380 HydrophobicContact CG2-CG2 3.83Å
361	I	90.7	Very high	87.4	Confident	3 Å²	3	36.3 Å²	36.3	2%	0.015	19%	0.194	C	C	.	.	S	Bend	trans	-103.8	116.6	-176.1	-52.9	175.8	0	0	0	108.4	S289 F357 S365 F366 T372 T375 F376	S289-I361 PolarHBondContact OG-O 3.25Å; S289-I361 VanDerWaalsContact OG-O 3.1Å; F357-I361 WeakPolarHBondContact O-CB 3.32Å; F357-I361 PolarHBondContact O-N 2.8Å; I361-S365 VanDerWaalsContact CG2-OG 3.24Å; I361-S365 WeakPolarHBondContact CG2-OG 3.32Å; I361-F366 HydrophobicContact CB-CD2 3.91Å; I361-F366 HydrophobicContact CB-CE2 4.01Å; I361-F366 HydrophobicContact CD1-CE2 4.25Å; I361-F366 HydrophobicContact CG2-CD2 3.58Å; I361-F366 HydrophobicContact CG2-CE2 4.16Å; I361-T372 HydrophobicContact CD1-CG2 3.95Å; I361-T375 HydrophobicContact CD1-CG2 3.94Å; I361-T375 HydrophobicContact CG1-CG2 4.23Å; I361-T375 HydrophobicContact CG2-CG2 4.48Å; I361-F376 HydrophobicContact CD1-CB 4.07Å
362	P	88.6	Confident	86.9	Confident	27 Å²	27	35.4 Å²	35.4	18%	0.175	19%	0.188	C	C	.	.			trans	-57.3	138	170.9	-24.1	33.7	0	0	0	111.6	S289 Y364 S365 F366	S289-P362 WeakPolarHBondContact OG-CA 3.49Å; P362-Y364 VanDerWaalsContact C-N 3.29Å; P362-Y364 HydrophobicContact CB-CD1 3.75Å; P362-Y364 HydrophobicContact CB-CE1 3.3Å; P362-Y364 HydrophobicContact CB-CE2 4.46Å; P362-Y364 HydrophobicContact CG-CE1 4.14Å; P362-Y364 PolarHBondContact O-N 3.49Å; P362-S365 WeakPolarHBondContact CD-OG 3.18Å; P362-S365 PolarHBondContact O-N 3.18Å; P362-S365 PolarHBondContact O-OG 2.97Å; P362-F366 PolarHBondContact O-N 3.41Å
363	A	86.5	Confident	86.4	Confident	23 Å²	23	32.6 Å²	32.6	19%	0.19	17%	0.174	C	C	.	.	G	3₁₀ helix	trans	-49.7	-42.9	-177.8	0	0	0	0	0	114	H116 V122 S289 S365 F366	H116-A363 PolarHBondContact NE2-O 2.9Å; V122-A363 HydrophobicContact CG2-CB 3.85Å; S289-A363 PolarHBondContact OG-N 3.42Å; A363-S365 VanDerWaalsContact C-N 3.28Å; A363-S365 PolarHBondContact O-N 3.21Å; A363-F366 WeakPolarHBondContact O-CB 3.45Å; A363-F366 PolarHBondContact O-N 2.95Å; A363-F366 VanDerWaalsContact O-N 3.12Å
364	Y	83.3	Confident	85.8	Confident	177 Å²	177	33.8 Å²	33.8	69%	0.694	18%	0.18	S	C	*	.	G	3₁₀ helix	trans	-63.4	-31.7	178.7	65.1	-96.2	0	0	0	113.4	P362 F366	P362-Y364 VanDerWaalsContact C-N 3.29Å; P362-Y364 HydrophobicContact CB-CD1 3.75Å; P362-Y364 HydrophobicContact CB-CE1 3.3Å; P362-Y364 HydrophobicContact CB-CE2 4.46Å; P362-Y364 HydrophobicContact CG-CE1 4.14Å; P362-Y364 PolarHBondContact O-N 3.49Å; Y364-F366 VanDerWaalsContact C-N 3.28Å; Y364-F366 PolarHBondContact O-N 3.32Å
365	S	84.8	Confident	85.5	Confident	17 Å²	17	35 Å²	35	12%	0.119	19%	0.187	C	C	.	.	G	3₁₀ helix	trans	-82.7	-5.5	179.1	66.5	0	0	0	0	113.6	I361 P362 A363 L367	I361-S365 VanDerWaalsContact CG2-OG 3.24Å; I361-S365 WeakPolarHBondContact CG2-OG 3.32Å; P362-S365 WeakPolarHBondContact CD-OG 3.18Å; P362-S365 PolarHBondContact O-N 3.18Å; P362-S365 PolarHBondContact O-OG 2.97Å; A363-S365 VanDerWaalsContact C-N 3.28Å; A363-S365 PolarHBondContact O-N 3.21Å; S365-L367 VanDerWaalsContact C-N 3.3Å
366	F	79.4	Confident	85.3	Confident	3 Å²	3	33.2 Å²	33.2	1%	0.013	18%	0.178	C	C	.	.	G	3₁₀ helix	trans	-71.5	-27.6	-178.8	-133.8	-98.7	0	0	0	112.1	P112 H116 F357 Y358 I361 P362 A363 Y364 T372	P112-F366 HydrophobicContact CB-CE1 3.51Å; P112-F366 HydrophobicContact CB-CZ 3.93Å; H116-F366 HydrophobicContact CB-CD1 3.91Å; H116-F366 HydrophobicContact CB-CE1 4.41Å; F357-F366 HydrophobicContact CB-CE2 3.96Å; F357-F366 HydrophobicContact CB-CZ 3.88Å; Y358-F366 HydrophobicContact CD1-CD2 4.14Å; Y358-F366 AromaticContact CD1-CE2 3.88Å; Y358-F366 HydrophobicContact CD1-CE2 3.88Å; Y358-F366 HydrophobicContact CD1-CZ 4.36Å; Y358-F366 HydrophobicContact CE1-CD1 4.43Å; Y358-F366 AromaticContact CE1-CD2 3.96Å; Y358-F366 HydrophobicContact CE1-CD2 3.96Å; Y358-F366 HydrophobicContact CE1-CE1 4.3Å; Y358-F366 AromaticContact CE1-CE2 3.84Å; Y358-F366 HydrophobicContact CE1-CE2 3.84Å; Y358-F366 HydrophobicContact CE1-CG 4.26Å; Y358-F366 HydrophobicContact CE1-CZ 4.01Å; I361-F366 HydrophobicContact CB-CD2 3.91Å; I361-F366 HydrophobicContact CB-CE2 4.01Å; I361-F366 HydrophobicContact CD1-CE2 4.25Å; I361-F366 HydrophobicContact CG2-CD2 3.58Å; I361-F366 HydrophobicContact CG2-CE2 4.16Å; P362-F366 PolarHBondContact O-N 3.41Å; A363-F366 WeakPolarHBondContact O-CB 3.45Å; A363-F366 PolarHBondContact O-N 2.95Å; A363-F366 VanDerWaalsContact O-N 3.12Å; Y364-F366 VanDerWaalsContact C-N 3.28Å; Y364-F366 PolarHBondContact O-N 3.32Å; F366-T372 HydrophobicContact CE1-CG2 3.8Å; F366-T372 HydrophobicContact CE2-CG2 3.81Å; F366-T372 HydrophobicContact CZ-CG2 3.33Å
367	L	78.9	Confident	85	Confident	73 Å²	73	33.2 Å²	33.2	38%	0.382	18%	0.178	S	C	.	.	S	Bend	trans	-77.7	-26.8	-178.9	-55.6	-177.3	0	0	0	112.6	K113 E117 S365 T369	K113-L367 WeakPolarHBondContact CE-O 3.26Å; K113-L367 PolarHBondContact NZ-O 3.38Å; E117-L367 HydrophobicContact CB-CD2 3.59Å; E117-L367 HydrophobicContact CG-CD2 4.02Å; S365-L367 VanDerWaalsContact C-N 3.3Å; L367-T369 VanDerWaalsContact C-N 3.29Å; L367-T369 PolarHBondContact O-N 3.42Å
368	D	80	Confident	84.8	Confident	133 Å²	133	38.1 Å²	38.1	71%	0.711	20%	0.204	S	C	*	.	S	Bend	trans	-76.9	-14.3	-177.2	-60.5	-35.3	0	0	0	113.3
369	T	72.9	Confident	84.6	Confident	32 Å²	32	43.2 Å²	43.2	20%	0.196	23%	0.226	C	C	.	.			trans	-117.2	121.9	-174.6	-45.6	0	0	0	0	113.2	K113 L367 A371 T375	K113-T369 WeakPolarHBondContact CD-O 3.47Å; L367-T369 VanDerWaalsContact C-N 3.29Å; L367-T369 PolarHBondContact O-N 3.42Å; T369-A371 VanDerWaalsContact C-N 3.29Å; T369-A371 WeakPolarHBondContact CG2-O 3.16Å; T369-A371 PolarHBondContact O-N 3.43Å; T369-T375 WeakPolarHBondContact CB-OG1 3.16Å; T369-T375 WeakPolarHBondContact CG2-OG1 3.45Å; T369-T375 PolarHBondContact OG1-OG1 3.04Å
370	D	66.9	Low	84.5	Confident	99 Å²	99	44.7 Å²	44.7	53%	0.529	23%	0.234	S	C	.	.	S	Bend	trans	-71.9	-19.7	172.7	-66.4	-21.7	0	0	0	114.5	K113	K113-D370 IonicContact NZ-OD1 2.73Å; K113-D370 PolarHBondContact NZ-OD1 3.43Å
371	A	75.9	Confident	84.5	Confident	16 Å²	16	45.9 Å²	45.9	13%	0.132	24%	0.236	C	C	.	.			trans	-124.3	81.1	-177.3	0	0	0	0	0	111.4	Y218 T369 A373 M374 T375	Y218-A371 HydrophobicContact CE1-CB 4.2Å; Y218-A371 WeakPolarHBondContact OH-CB 3.28Å; T369-A371 VanDerWaalsContact C-N 3.29Å; T369-A371 WeakPolarHBondContact CG2-O 3.16Å; T369-A371 PolarHBondContact O-N 3.43Å; A371-A373 PolarHBondContact O-N 3.43Å; A371-A373 VanDerWaalsContact O-N 3.12Å; A371-M374 HydrophobicContact CB-CB 3.99Å; A371-M374 HydrophobicContact CB-CG 3.69Å; A371-M374 WeakPolarHBondContact O-CB 3.36Å; A371-M374 PolarHBondContact O-N 2.88Å; A371-T375 PolarHBondContact O-N 3.49Å
372	T	85.6	Confident	84.2	Confident	2 Å²	2	48 Å²	48	1%	0.012	26%	0.259	C	S	.	.	H	α-helix	trans	-51	-40.7	-177	-48.7	0	0	0	0	112.9	F109 P112 F357 I361 F366 M374 T375 F376	F109-T372 PolarHBondContact O-N 3.11Å; P112-T372 HydrophobicContact CB-CG2 4.2Å; F357-T372 HydrophobicContact CB-CG2 4.05Å; F357-T372 HydrophobicContact CD1-CG2 4.17Å; F357-T372 HydrophobicContact CD2-CG2 3.64Å; F357-T372 HydrophobicContact CE2-CG2 4.05Å; F357-T372 HydrophobicContact CG-CG2 3.71Å; F357-T372 HydrophobicContact CZ-CG2 4.49Å; I361-T372 HydrophobicContact CD1-CG2 3.95Å; F366-T372 HydrophobicContact CE1-CG2 3.8Å; F366-T372 HydrophobicContact CE2-CG2 3.81Å; F366-T372 HydrophobicContact CZ-CG2 3.33Å; T372-M374 VanDerWaalsContact C-N 3.33Å; T372-M374 PolarHBondContact O-N 2.9Å; T372-T375 PolarHBondContact O-N 3.38Å; T372-F376 WeakPolarHBondContact O-CB 3.45Å; T372-F376 PolarHBondContact O-N 3.38Å
373	A	86.4	Confident	84.1	Confident	2 Å²	2	52 Å²	52	2%	0.017	29%	0.287	C	S	.	.	H	α-helix	trans	-63.2	-36.8	179	0	0	0	0	0	113.2	F109 F357 A371 F376 A377 M388 V392	F109-A373 HydrophobicContact CB-CB 4.13Å; F109-A373 HydrophobicContact CD1-CB 3.74Å; F109-A373 HydrophobicContact CG-CB 4.32Å; F357-A373 HydrophobicContact CE1-CB 4.48Å; F357-A373 HydrophobicContact CZ-CB 4.21Å; A371-A373 PolarHBondContact O-N 3.43Å; A371-A373 VanDerWaalsContact O-N 3.12Å; A373-F376 PolarHBondContact O-N 2.97Å; A373-A377 WeakPolarHBondContact O-CB 3.33Å; A373-A377 PolarHBondContact O-N 3.27Å; A373-M388 HydrophobicContact CB-CG 4.03Å; A373-M388 HydrophobicContact CB-SD 4.1Å; A373-M388 WeakPolarHBondContact O-CG 3.2Å; A373-V392 HydrophobicContact CB-CG2 4.4Å
374	M	85.4	Confident	84.2	Confident	25 Å²	25	57.5 Å²	57.5	12%	0.123	31%	0.307	C	S	.	.	H	α-helix	trans	-67.8	-45.5	178.7	-65.1	-60.9	-58.9	0	0	111.1	Y218 V221 A371 T372 F376 A377 N378 M388 P389	Y218-M374 HydrophobicContact CE1-CG 4.09Å; Y218-M374 HydrophobicContact CE1-SD 4.47Å; V221-M374 HydrophobicContact CG1-CE 3.98Å; A371-M374 HydrophobicContact CB-CB 3.99Å; A371-M374 HydrophobicContact CB-CG 3.69Å; A371-M374 WeakPolarHBondContact O-CB 3.36Å; A371-M374 PolarHBondContact O-N 2.88Å; T372-M374 VanDerWaalsContact C-N 3.33Å; T372-M374 PolarHBondContact O-N 2.9Å; M374-F376 VanDerWaalsContact C-N 3.32Å; M374-F376 PolarHBondContact O-N 3.06Å; M374-A377 PolarHBondContact O-N 3.4Å; M374-N378 WeakPolarHBondContact O-CB 3.46Å; M374-N378 PolarHBondContact O-N 2.99Å; M374-N378 PolarHBondContact O-ND2 2.95Å; M374-M388 HydrophobicContact SD-CB 4.22Å; M374-M388 HydrophobicContact SD-CG 4.21Å; M374-P389 HydrophobicContact CE-CB 3.91Å; M374-P389 HydrophobicContact CE-CG 3.73Å; M374-P389 HydrophobicContact SD-CB 3.62Å; M374-P389 WeakPolarHBondContact SD-CD 3.46Å; M374-P389 HydrophobicContact SD-CG 3.92Å
375	T	88.2	Confident	84.4	Confident	26 Å²	26	49.2 Å²	49.2	16%	0.16	28%	0.276	C	S	.	.	H	α-helix	trans	-62.9	-40.2	176.1	-66.3	0	0	0	0	111.7	I361 T369 A371 T372 K379	I361-T375 HydrophobicContact CD1-CG2 3.94Å; I361-T375 HydrophobicContact CG1-CG2 4.23Å; I361-T375 HydrophobicContact CG2-CG2 4.48Å; T369-T375 WeakPolarHBondContact CB-OG1 3.16Å; T369-T375 WeakPolarHBondContact CG2-OG1 3.45Å; T369-T375 PolarHBondContact OG1-OG1 3.04Å; A371-T375 PolarHBondContact O-N 3.49Å; T372-T375 PolarHBondContact O-N 3.38Å; T375-K379 HydrophobicContact CG2-CD 4.38Å; T375-K379 WeakPolarHBondContact O-CB 3.37Å; T375-K379 WeakPolarHBondContact O-CG 3.49Å; T375-K379 PolarHBondContact O-N 3.31Å; T375-K379 VanDerWaalsContact O-N 3.09Å
376	F	90.7	Very high	84.5	Confident	0 Å²	0	55.3 Å²	55.3	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-58.7	-49.8	173.2	179.1	-89.7	0	0	0	111.2	I274 T277 A356 F357 V360 I361 T372 A373 M374 N378 K379 V380 Y381	I274-F376 HydrophobicContact CB-CE1 4.36Å; I274-F376 HydrophobicContact CG1-CE1 4.26Å; I274-F376 HydrophobicContact CG2-CD1 4.31Å; I274-F376 HydrophobicContact CG2-CE1 3.91Å; I274-F376 HydrophobicContact CG2-CZ 4.02Å; T277-F376 HydrophobicContact CG2-CE1 4.32Å; T277-F376 HydrophobicContact CG2-CZ 4Å; A356-F376 WeakPolarHBondContact O-CE2 3.38Å; F357-F376 HydrophobicContact CD1-CB 3.86Å; F357-F376 AromaticContact CD1-CD2 3.75Å; F357-F376 HydrophobicContact CD1-CD2 3.75Å; F357-F376 HydrophobicContact CD1-CE2 4.48Å; F357-F376 AromaticContact CD1-CG 3.84Å; F357-F376 HydrophobicContact CD1-CG 3.84Å; F357-F376 HydrophobicContact CE1-CB 3.97Å; F357-F376 HydrophobicContact CE1-CD2 4.39Å; F357-F376 HydrophobicContact CE1-CG 4.05Å; V360-F376 HydrophobicContact CB-CD2 3.74Å; V360-F376 HydrophobicContact CB-CE2 3.75Å; V360-F376 HydrophobicContact CG1-CD2 3.95Å; V360-F376 HydrophobicContact CG1-CE2 4.23Å; V360-F376 HydrophobicContact CG2-CD2 3.97Å; V360-F376 HydrophobicContact CG2-CE2 3.42Å; V360-F376 VanDerWaalsContact CG2-CE2 3.42Å; V360-F376 HydrophobicContact CG2-CZ 4.25Å; I361-F376 HydrophobicContact CD1-CB 4.07Å; T372-F376 WeakPolarHBondContact O-CB 3.45Å; T372-F376 PolarHBondContact O-N 3.38Å; A373-F376 PolarHBondContact O-N 2.97Å; M374-F376 VanDerWaalsContact C-N 3.32Å; M374-F376 PolarHBondContact O-N 3.06Å; F376-N378 PolarHBondContact O-N 2.98Å; F376-K379 PolarHBondContact O-N 2.86Å; F376-V380 HydrophobicContact CE2-CG2 4.48Å; F376-V380 HydrophobicContact CZ-CG2 4.41Å; F376-V380 WeakPolarHBondContact O-CG2 3.33Å; F376-V380 PolarHBondContact O-N 3.29Å; F376-V380 VanDerWaalsContact O-N 3.16Å; F376-Y381 HydrophobicContact CD1-CE2 4.42Å; F376-Y381 HydrophobicContact CE1-CE2 4.1Å
377	A	90.1	Very high	84.9	Confident	0 Å²	0	59 Å²	59	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-63.4	-43.3	-178.8	0	0	0	0	0	112.7	A373 M374 K379 V380 Y381 A385 M388	A373-A377 WeakPolarHBondContact O-CB 3.33Å; A373-A377 PolarHBondContact O-N 3.27Å; M374-A377 PolarHBondContact O-N 3.4Å; A377-K379 VanDerWaalsContact C-N 3.31Å; A377-K379 PolarHBondContact O-N 2.99Å; A377-V380 PolarHBondContact O-N 3.44Å; A377-Y381 HydrophobicContact CB-CD2 3.95Å; A377-Y381 WeakPolarHBondContact O-CA 3.38Å; A377-Y381 WeakPolarHBondContact O-CB 3.44Å; A377-Y381 PolarHBondContact O-N 3.42Å; A377-A385 HydrophobicContact CB-CB 4.21Å; A377-M388 HydrophobicContact CB-CB 3.45Å; A377-M388 VanDerWaalsContact CB-CB 3.45Å; A377-M388 HydrophobicContact CB-CE 3.93Å; A377-M388 HydrophobicContact CB-CG 3.78Å
378	N	89.4	Confident	85.4	Confident	103 Å²	103	56 Å²	56	55%	0.551	30%	0.299	S	S	*	.	H	α-helix	trans	-62.9	-36.6	177.5	-76	-30.2	0	0	0	112.2	M374 F376 A385	M374-N378 WeakPolarHBondContact O-CB 3.46Å; M374-N378 PolarHBondContact O-N 2.99Å; M374-N378 PolarHBondContact O-ND2 2.95Å; F376-N378 PolarHBondContact O-N 2.98Å; N378-A385 WeakPolarHBondContact OD1-CB 3.36Å
379	K	89.3	Confident	85.8	Confident	107 Å²	107	49.8 Å²	49.8	47%	0.465	27%	0.266	S	S	.	.	H	α-helix	trans	-72.6	-30.1	178.4	-77.7	-174.3	174.8	-178.6	0	113.9	V360 T375 F376 A377	V360-K379 HydrophobicContact CG1-CB 3.86Å; V360-K379 HydrophobicContact CG1-CD 4.23Å; T375-K379 HydrophobicContact CG2-CD 4.38Å; T375-K379 WeakPolarHBondContact O-CB 3.37Å; T375-K379 WeakPolarHBondContact O-CG 3.49Å; T375-K379 PolarHBondContact O-N 3.31Å; T375-K379 VanDerWaalsContact O-N 3.09Å; F376-K379 PolarHBondContact O-N 2.86Å; A377-K379 VanDerWaalsContact C-N 3.31Å; A377-K379 PolarHBondContact O-N 2.99Å
380	V	90.4	Very high	86.6	Confident	44 Å²	44	51.5 Å²	51.5	27%	0.267	27%	0.273	S	S	.	.	H	α-helix	trans	-112.8	-42.6	-170	-172.4	0	0	0	0	113.8	T277 V360 F376 A377	T277-V380 HydrophobicContact CG2-CB 4.31Å; T277-V380 HydrophobicContact CG2-CG1 3.38Å; V360-V380 HydrophobicContact CB-CG2 4.26Å; V360-V380 HydrophobicContact CG1-CG2 3.41Å; V360-V380 VanDerWaalsContact CG1-CG2 3.41Å; V360-V380 HydrophobicContact CG2-CG2 3.83Å; F376-V380 HydrophobicContact CE2-CG2 4.48Å; F376-V380 HydrophobicContact CZ-CG2 4.41Å; F376-V380 WeakPolarHBondContact O-CG2 3.33Å; F376-V380 PolarHBondContact O-N 3.29Å; F376-V380 VanDerWaalsContact O-N 3.16Å; A377-V380 PolarHBondContact O-N 3.44Å
381	Y	90.3	Very high	87.7	Confident	51 Å²	51	47.9 Å²	47.9	20%	0.2	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-90.6	-10	-172.3	-61.8	-42.5	0	0	0	113.7	L273 T277 F376 A377 S383 F384 M388	L273-Y381 HydrophobicContact CD2-CE1 4.26Å; L273-Y381 HydrophobicContact CD2-CE2 4.07Å; L273-Y381 WeakPolarHBondContact CD2-OH 3.37Å; T277-Y381 VanDerWaalsContact CB-OH 3.25Å; T277-Y381 WeakPolarHBondContact CB-OH 3.47Å; T277-Y381 HydrophobicContact CG2-CE1 3.78Å; T277-Y381 WeakPolarHBondContact CG2-OH 3.41Å; T277-Y381 PolarHBondContact OG1-OH 3Å; F376-Y381 HydrophobicContact CD1-CE2 4.42Å; F376-Y381 HydrophobicContact CE1-CE2 4.1Å; A377-Y381 HydrophobicContact CB-CD2 3.95Å; A377-Y381 WeakPolarHBondContact O-CA 3.38Å; A377-Y381 WeakPolarHBondContact O-CB 3.44Å; A377-Y381 PolarHBondContact O-N 3.42Å; Y381-S383 PolarHBondContact O-N 3.26Å; Y381-F384 PolarHBondContact O-N 3.49Å; Y381-M388 HydrophobicContact CD2-CE 4.41Å; Y381-M388 HydrophobicContact CE2-CE 3.91Å
382	G	86.2	Confident	88.3	Confident	48 Å²	48	47.1 Å²	47.1	50%	0.495	25%	0.247	S	C	.	.	G	3₁₀ helix	trans	50.9	-115.3	177.4	0	0	0	0	0	111.4	F384 A385	G382-F384 PolarHBondContact O-N 3.02Å; G382-F384 VanDerWaalsContact O-N 3.07Å; G382-A385 WeakPolarHBondContact O-CB 3.43Å; G382-A385 PolarHBondContact O-N 3.34Å
383	S	86.5	Confident	88.5	Confident	111 Å²	111	47.2 Å²	47.2	78%	0.776	25%	0.248	S	C	*	.	G	3₁₀ helix	trans	-59.2	-18.3	178.6	-52	0	0	0	0	115	Y381 W386	Y381-S383 PolarHBondContact O-N 3.26Å; S383-W386 PolarHBondContact O-NE1 3.17Å
384	F	87.5	Confident	88.8	Confident	138 Å²	138	49.8 Å²	49.8	61%	0.605	27%	0.265	S	S	*	.	G	3₁₀ helix	trans	-95.9	4.9	176.8	-63.8	-73.4	0	0	0	113.4	Y381 G382 W386 I387	Y381-F384 PolarHBondContact O-N 3.49Å; G382-F384 PolarHBondContact O-N 3.02Å; G382-F384 VanDerWaalsContact O-N 3.07Å; F384-W386 PolarHBondContact O-N 2.9Å; F384-I387 HydrophobicContact CB-CD1 4.11Å; F384-I387 HydrophobicContact CD1-CD1 4.02Å; F384-I387 WeakPolarHBondContact O-CB 3.33Å; F384-I387 WeakPolarHBondContact O-CG1 3.28Å; F384-I387 PolarHBondContact O-N 3.46Å; F384-I387 VanDerWaalsContact O-N 3.11Å
385	A	87.7	Confident	89	Confident	4 Å²	4	48.6 Å²	48.6	3%	0.033	26%	0.259	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.4	-26.7	-177.4	0	0	0	0	0	113.9	A377 N378 G382 I387 M388 P389	A377-A385 HydrophobicContact CB-CB 4.21Å; N378-A385 WeakPolarHBondContact OD1-CB 3.36Å; G382-A385 WeakPolarHBondContact O-CB 3.43Å; G382-A385 PolarHBondContact O-N 3.34Å; A385-I387 PolarHBondContact O-N 2.91Å; A385-I387 VanDerWaalsContact O-N 3.13Å; A385-M388 WeakPolarHBondContact O-CB 3.46Å; A385-M388 PolarHBondContact O-N 3.45Å; A385-M388 VanDerWaalsContact O-N 3.13Å; A385-P389 WeakPolarHBondContact O-CD 3.42Å
386	W	86.5	Confident	89.1	Confident	144 Å²	144	47.4 Å²	47.4	55%	0.545	25%	0.251	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-15	175.8	68.4	-93.5	0	0	0	114	S383 F384 P389 I390	S383-W386 PolarHBondContact O-NE1 3.17Å; F384-W386 PolarHBondContact O-N 2.9Å; W386-P389 VanDerWaalsContact O-CD 3.24Å; W386-P389 WeakPolarHBondContact O-CD 3.28Å; W386-P389 VanDerWaalsContact O-CG 3.23Å; W386-P389 WeakPolarHBondContact O-CG 3.43Å; W386-I390 HydrophobicContact CE3-CD1 3.54Å; W386-I390 HydrophobicContact CZ3-CD1 3.46Å; W386-I390 VanDerWaalsContact CZ3-CD1 3.46Å
387	I	88.4	Confident	89.2	Confident	82 Å²	82	48.5 Å²	48.5	42%	0.421	26%	0.258	S	S	.	.	H	α-helix	trans	-70.6	-34.5	175.2	-63.2	176.6	0	0	0	111	F384 A385 I390 F391	F384-I387 HydrophobicContact CB-CD1 4.11Å; F384-I387 HydrophobicContact CD1-CD1 4.02Å; F384-I387 WeakPolarHBondContact O-CB 3.33Å; F384-I387 WeakPolarHBondContact O-CG1 3.28Å; F384-I387 PolarHBondContact O-N 3.46Å; F384-I387 VanDerWaalsContact O-N 3.11Å; A385-I387 PolarHBondContact O-N 2.91Å; A385-I387 VanDerWaalsContact O-N 3.13Å; I387-I390 PolarHBondContact O-N 3.42Å; I387-F391 WeakPolarHBondContact O-CB 3.36Å; I387-F391 PolarHBondContact O-N 3.43Å
388	M	89	Confident	89.3	Confident	10 Å²	10	48.5 Å²	48.5	5%	0.049	26%	0.258	C	S	.	.	H	α-helix	trans	-58.9	-49.2	-177.3	-168.5	60.1	65.7	0	0	114.7	I274 A373 M374 A377 Y381 A385 I390 F391 V392	I274-M388 HydrophobicContact CD1-CE 3.72Å; I274-M388 HydrophobicContact CD1-SD 3.96Å; I274-M388 HydrophobicContact CG1-CE 3.82Å; A373-M388 HydrophobicContact CB-CG 4.03Å; A373-M388 HydrophobicContact CB-SD 4.1Å; A373-M388 WeakPolarHBondContact O-CG 3.2Å; M374-M388 HydrophobicContact SD-CB 4.22Å; M374-M388 HydrophobicContact SD-CG 4.21Å; A377-M388 HydrophobicContact CB-CB 3.45Å; A377-M388 VanDerWaalsContact CB-CB 3.45Å; A377-M388 HydrophobicContact CB-CE 3.93Å; A377-M388 HydrophobicContact CB-CG 3.78Å; Y381-M388 HydrophobicContact CD2-CE 4.41Å; Y381-M388 HydrophobicContact CE2-CE 3.91Å; A385-M388 WeakPolarHBondContact O-CB 3.46Å; A385-M388 PolarHBondContact O-N 3.45Å; A385-M388 VanDerWaalsContact O-N 3.13Å; M388-I390 VanDerWaalsContact C-N 3.33Å; M388-I390 PolarHBondContact O-N 2.96Å; M388-F391 WeakPolarHBondContact O-CB 3.37Å; M388-F391 PolarHBondContact O-N 2.96Å; M388-F391 VanDerWaalsContact O-N 3.17Å; M388-F391 HydrophobicContact SD-CD1 3.97Å; M388-V392 WeakPolarHBondContact O-CG2 3.46Å; M388-V392 PolarHBondContact O-N 3.27Å
389	P	88.6	Confident	89.3	Confident	1 Å²	1	43.8 Å²	43.8	1%	0.006	23%	0.233	C	C	.	.	H	α-helix	trans	-63.2	-38.4	177.7	24.5	-34.6	0	0	0	112.1	Y218 V221 P222 M374 A385 W386 F391 V392 A393	Y218-P389 HydrophobicContact CD1-CB 4.28Å; V221-P389 HydrophobicContact CB-CB 4.17Å; V221-P389 HydrophobicContact CG1-CB 4.11Å; V221-P389 HydrophobicContact CG1-CG 4.3Å; P222-P389 HydrophobicContact CG-CB 4.14Å; P222-P389 HydrophobicContact CG-CG 3.64Å; M374-P389 HydrophobicContact CE-CB 3.91Å; M374-P389 HydrophobicContact CE-CG 3.73Å; M374-P389 HydrophobicContact SD-CB 3.62Å; M374-P389 WeakPolarHBondContact SD-CD 3.46Å; M374-P389 HydrophobicContact SD-CG 3.92Å; A385-P389 WeakPolarHBondContact O-CD 3.42Å; W386-P389 VanDerWaalsContact O-CD 3.24Å; W386-P389 WeakPolarHBondContact O-CD 3.28Å; W386-P389 VanDerWaalsContact O-CG 3.23Å; W386-P389 WeakPolarHBondContact O-CG 3.43Å; P389-F391 VanDerWaalsContact C-N 3.29Å; P389-F391 PolarHBondContact O-N 2.71Å; P389-V392 PolarHBondContact O-N 2.9Å; P389-A393 VanDerWaalsContact O-CB 3.29Å; P389-A393 WeakPolarHBondContact O-CB 3.25Å; P389-A393 PolarHBondContact O-N 2.94Å
390	I	90.1	Very high	89.4	Confident	69 Å²	69	38.7 Å²	38.7	35%	0.354	21%	0.211	S	C	.	.	H	α-helix	trans	-62.1	-42.1	174.7	-63	177.6	0	0	0	110.3	P222 W386 I387 M388 A393 C394	P222-I390 HydrophobicContact CG-CD1 4.46Å; P222-I390 HydrophobicContact CG-CG1 3.91Å; W386-I390 HydrophobicContact CE3-CD1 3.54Å; W386-I390 HydrophobicContact CZ3-CD1 3.46Å; W386-I390 VanDerWaalsContact CZ3-CD1 3.46Å; I387-I390 PolarHBondContact O-N 3.42Å; M388-I390 VanDerWaalsContact C-N 3.33Å; M388-I390 PolarHBondContact O-N 2.96Å; I390-A393 WeakPolarHBondContact O-CB 3.44Å; I390-A393 PolarHBondContact O-N 3.42Å; I390-C394 WeakPolarHBondContact O-CB 3.36Å; I390-C394 PolarHBondContact O-N 3.41Å; I390-C394 PolarHBondContact O-SG 3.4Å; I390-C394 VanDerWaalsContact O-SG 3.38Å
391	F	89.4	Confident	89.5	Confident	23 Å²	23	36.6 Å²	36.6	10%	0.101	20%	0.199	C	C	.	.	H	α-helix	trans	-62.1	-47.5	176.4	170	-108.4	0	0	0	112.3	F109 A266 K267 A270 I387 M388 P389 A393 C394 S395	F109-F391 HydrophobicContact CE1-CD1 4.39Å; F109-F391 AromaticContact CE1-CE1 3.72Å; F109-F391 HydrophobicContact CE1-CE1 3.72Å; F109-F391 HydrophobicContact CE2-CE1 4.39Å; F109-F391 HydrophobicContact CZ-CD1 4.19Å; F109-F391 AromaticContact CZ-CE1 3.38Å; F109-F391 HydrophobicContact CZ-CE1 3.38Å; F109-F391 HydrophobicContact CZ-CZ 4.03Å; A266-F391 WeakPolarHBondContact O-CE2 3.36Å; K267-F391 WeakPolarHBondContact O-CZ 3.49Å; A270-F391 HydrophobicContact CB-CD1 3.91Å; A270-F391 HydrophobicContact CB-CD2 3.33Å; A270-F391 HydrophobicContact CB-CE1 3.65Å; A270-F391 HydrophobicContact CB-CE2 3.06Å; A270-F391 HydrophobicContact CB-CG 3.76Å; A270-F391 HydrophobicContact CB-CZ 3.24Å; I387-F391 WeakPolarHBondContact O-CB 3.36Å; I387-F391 PolarHBondContact O-N 3.43Å; M388-F391 WeakPolarHBondContact O-CB 3.37Å; M388-F391 PolarHBondContact O-N 2.96Å; M388-F391 VanDerWaalsContact O-N 3.17Å; M388-F391 HydrophobicContact SD-CD1 3.97Å; P389-F391 VanDerWaalsContact C-N 3.29Å; P389-F391 PolarHBondContact O-N 2.71Å; F391-A393 VanDerWaalsContact C-N 3.31Å; F391-A393 PolarHBondContact O-N 3.26Å; F391-C394 PolarHBondContact O-N 2.99Å; F391-S395 PolarHBondContact O-N 2.89Å
392	V	88.5	Confident	89.5	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-61.8	-41.1	175.9	176.9	0	0	0	0	110.6	F109 Y218 A373 M388 P389 S395 T396	F109-V392 HydrophobicContact CB-CG1 4.38Å; F109-V392 HydrophobicContact CB-CG2 4.27Å; F109-V392 HydrophobicContact CD1-CG2 4.02Å; F109-V392 HydrophobicContact CD2-CB 4.37Å; F109-V392 HydrophobicContact CD2-CG1 3.86Å; F109-V392 HydrophobicContact CD2-CG2 3.91Å; F109-V392 HydrophobicContact CE1-CG2 4.33Å; F109-V392 HydrophobicContact CE2-CG1 4.49Å; F109-V392 HydrophobicContact CE2-CG2 4.24Å; F109-V392 HydrophobicContact CG-CG1 4.26Å; F109-V392 HydrophobicContact CG-CG2 3.8Å; F109-V392 HydrophobicContact CZ-CG2 4.45Å; Y218-V392 HydrophobicContact CD1-CB 4.23Å; Y218-V392 HydrophobicContact CD1-CG1 4.05Å; Y218-V392 HydrophobicContact CD2-CB 4.41Å; Y218-V392 HydrophobicContact CD2-CG1 3.52Å; Y218-V392 HydrophobicContact CE1-CG1 4.16Å; Y218-V392 HydrophobicContact CE2-CG1 3.63Å; Y218-V392 HydrophobicContact CG-CB 4.15Å; Y218-V392 HydrophobicContact CG-CG1 3.74Å; A373-V392 HydrophobicContact CB-CG2 4.4Å; M388-V392 WeakPolarHBondContact O-CG2 3.46Å; M388-V392 PolarHBondContact O-N 3.27Å; P389-V392 PolarHBondContact O-N 2.9Å; V392-S395 VanDerWaalsContact O-CB 3.27Å; V392-S395 WeakPolarHBondContact O-CB 3.5Å; V392-S395 PolarHBondContact O-N 3.48Å; V392-T396 WeakPolarHBondContact O-CG2 3.46Å; V392-T396 PolarHBondContact O-N 3.4Å; V392-T396 PolarHBondContact O-OG1 3.11Å
393	A	90.4	Very high	89.5	Confident	4 Å²	4	32.1 Å²	32.1	3%	0.033	17%	0.167	C	C	.	.	H	α-helix	trans	-59.5	-52.9	175.1	0	0	0	0	0	111.2	F215 A219 P389 I390 F391 S395 T396 V397	F215-A393 HydrophobicContact CD2-CB 3.86Å; F215-A393 HydrophobicContact CE2-CB 4.28Å; A219-A393 HydrophobicContact CB-CB 4.15Å; P389-A393 VanDerWaalsContact O-CB 3.29Å; P389-A393 WeakPolarHBondContact O-CB 3.25Å; P389-A393 PolarHBondContact O-N 2.94Å; I390-A393 WeakPolarHBondContact O-CB 3.44Å; I390-A393 PolarHBondContact O-N 3.42Å; F391-A393 VanDerWaalsContact C-N 3.31Å; F391-A393 PolarHBondContact O-N 3.26Å; A393-S395 PolarHBondContact O-N 3.26Å; A393-T396 PolarHBondContact O-N 2.96Å; A393-T396 PolarHBondContact O-OG1 3.16Å; A393-V397 WeakPolarHBondContact O-CG2 3.5Å; A393-V397 PolarHBondContact O-N 3.07Å; A393-V397 VanDerWaalsContact O-N 3.08Å
394	C	91.4	Very high	89.6	Confident	56 Å²	56	26.9 Å²	26.9	38%	0.378	13%	0.13	S	C	.	.	H	α-helix	trans	-56.7	-36.8	174.1	-74	0	0	0	0	112.4	L263 I390 F391 V397 G398	L263-C394 HydrophobicContact CD2-CB 4.5Å; I390-C394 WeakPolarHBondContact O-CB 3.36Å; I390-C394 PolarHBondContact O-N 3.41Å; I390-C394 PolarHBondContact O-SG 3.4Å; I390-C394 VanDerWaalsContact O-SG 3.38Å; F391-C394 PolarHBondContact O-N 2.99Å; C394-V397 PolarHBondContact O-N 3.01Å; C394-G398 PolarHBondContact O-N 2.85Å
395	S	91	Very high	89.7	Confident	0 Å²	0	20.3 Å²	20.3	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-58.6	-52.1	174	-174.5	0	0	0	0	110.7	I104 G105 K267 F391 V392 A393 V397 G398 S399	I104-S395 PolarHBondContact O-OG 2.91Å; G105-S395 PolarHBondContact O-OG 3.19Å; K267-S395 WeakPolarHBondContact CE-O 3.39Å; K267-S395 PolarHBondContact NZ-O 3.02Å; F391-S395 PolarHBondContact O-N 2.89Å; V392-S395 VanDerWaalsContact O-CB 3.27Å; V392-S395 WeakPolarHBondContact O-CB 3.5Å; V392-S395 PolarHBondContact O-N 3.48Å; A393-S395 PolarHBondContact O-N 3.26Å; S395-V397 VanDerWaalsContact C-N 3.31Å; S395-V397 PolarHBondContact O-N 2.79Å; S395-G398 PolarHBondContact O-N 3.14Å; S395-S399 PolarHBondContact O-N 2.9Å; S395-S399 VanDerWaalsContact O-N 3.16Å
396	T	89	Confident	89.7	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-64.8	-31.6	-178	55.4	0	0	0	0	113.9	T211 T214 F215 V392 A393 G398 S399 C400	T211-T396 WeakPolarHBondContact O-CB 3.25Å; T214-T396 HydrophobicContact CG2-CG2 3.87Å; F215-T396 WeakPolarHBondContact CA-OG1 3.48Å; F215-T396 VanDerWaalsContact CB-OG1 3.23Å; F215-T396 WeakPolarHBondContact CB-OG1 3.21Å; F215-T396 PolarHBondContact N-OG1 3.2Å; V392-T396 WeakPolarHBondContact O-CG2 3.46Å; V392-T396 PolarHBondContact O-N 3.4Å; V392-T396 PolarHBondContact O-OG1 3.11Å; A393-T396 PolarHBondContact O-N 2.96Å; A393-T396 PolarHBondContact O-OG1 3.16Å; T396-G398 VanDerWaalsContact C-N 3.35Å; T396-G398 PolarHBondContact O-N 2.93Å; T396-S399 PolarHBondContact O-N 3.4Å; T396-C400 WeakPolarHBondContact O-CB 3.47Å; T396-C400 PolarHBondContact O-N 3.41Å
397	V	92.9	Very high	89.6	Confident	24 Å²	24	13.2 Å²	13.2	15%	0.145	7%	0.074	C	C	.	.	H	α-helix	trans	-60	-44.7	171.1	176.6	0	0	0	0	111.2	F215 L245 L263 A393 C394 S395 S399 C400 N401	F215-V397 HydrophobicContact CB-CG2 4.29Å; F215-V397 HydrophobicContact CD2-CG2 3.27Å; F215-V397 HydrophobicContact CE2-CG2 3.64Å; F215-V397 HydrophobicContact CG-CG2 3.77Å; F215-V397 HydrophobicContact CZ-CG2 4.4Å; L245-V397 HydrophobicContact CD1-CG1 4.22Å; L245-V397 HydrophobicContact CD2-CG1 4.17Å; L263-V397 HydrophobicContact CD1-CB 4.37Å; L263-V397 HydrophobicContact CD1-CG1 3.93Å; A393-V397 WeakPolarHBondContact O-CG2 3.5Å; A393-V397 PolarHBondContact O-N 3.07Å; A393-V397 VanDerWaalsContact O-N 3.08Å; C394-V397 PolarHBondContact O-N 3.01Å; S395-V397 VanDerWaalsContact C-N 3.31Å; S395-V397 PolarHBondContact O-N 2.79Å; V397-S399 VanDerWaalsContact C-N 3.3Å; V397-S399 PolarHBondContact O-N 3.16Å; V397-C400 WeakPolarHBondContact O-CB 3.3Å; V397-C400 PolarHBondContact O-N 2.65Å; V397-N401 PolarHBondContact O-N 3.08Å
398	G	91.8	Very high	89.5	Confident	0 Å²	0	9.3 Å²	9.3	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-65.9	-33.2	178.9	0	0	0	0	0	112.8	Q260 L263 C394 S395 T396 G402	Q260-G398 PolarHBondContact NE2-O 2.75Å; Q260-G398 VanDerWaalsContact NE2-O 3.14Å; Q260-G398 PolarHBondContact OE1-O 3.24Å; L263-G398 VanDerWaalsContact CD1-CA 3.47Å; C394-G398 PolarHBondContact O-N 2.85Å; S395-G398 PolarHBondContact O-N 3.14Å; T396-G398 VanDerWaalsContact C-N 3.35Å; T396-G398 PolarHBondContact O-N 2.93Å; G398-G402 PolarHBondContact O-N 3.44Å
399	S	91.3	Very high	89.5	Confident	4 Å²	4	8.9 Å²	8.9	3%	0.028	5%	0.051	C	C	.	.	H	α-helix	trans	-72.6	-41	174.4	-59.5	0	0	0	0	111.1	G101 C102 I104 G105 K267 S395 T396 V397 N401 G402 V403	G101-S399 PolarHBondContact O-OG 3.36Å; C102-S399 PolarHBondContact O-OG 3.43Å; I104-S399 PolarHBondContact O-OG 2.93Å; I104-S399 VanDerWaalsContact O-OG 3.11Å; G105-S399 WeakPolarHBondContact CA-OG 3.43Å; G105-S399 PolarHBondContact N-OG 3.29Å; K267-S399 PolarHBondContact NZ-OG 3.34Å; K267-S399 VanDerWaalsContact NZ-OG 3.16Å; S395-S399 PolarHBondContact O-N 2.9Å; S395-S399 VanDerWaalsContact O-N 3.16Å; T396-S399 PolarHBondContact O-N 3.4Å; V397-S399 VanDerWaalsContact C-N 3.3Å; V397-S399 PolarHBondContact O-N 3.16Å; S399-N401 VanDerWaalsContact C-N 3.33Å; S399-N401 PolarHBondContact O-N 2.97Å; S399-G402 PolarHBondContact O-N 3.21Å; S399-V403 WeakPolarHBondContact O-CG2 3.27Å; S399-V403 PolarHBondContact O-N 2.93Å
400	C	89.8	Confident	89.4	Confident	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-58.5	-44.3	175.9	-169.6	0	0	0	0	111.9	T211 L245 T396 V397 G402 V403 I404	T211-C400 WeakPolarHBondContact OG1-CA 3.43Å; T211-C400 VanDerWaalsContact OG1-CB 3.29Å; T211-C400 WeakPolarHBondContact OG1-CB 3.45Å; L245-C400 HydrophobicContact CD1-CB 3.77Å; T396-C400 WeakPolarHBondContact O-CB 3.47Å; T396-C400 PolarHBondContact O-N 3.41Å; V397-C400 WeakPolarHBondContact O-CB 3.3Å; V397-C400 PolarHBondContact O-N 2.65Å; C400-G402 PolarHBondContact O-N 3.49Å; C400-V403 PolarHBondContact O-N 3.35Å; C400-I404 WeakPolarHBondContact O-CG1 3.09Å; C400-I404 PolarHBondContact O-N 3.13Å
401	N	92.9	Very high	89	Confident	0 Å²	0	5.5 Å²	5.5	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-60.1	-46.5	176.4	-179.5	55.8	0	0	0	111.9	L245 N249 A256 Q260 V397 S399 V403 I404 L405	L245-N401 HydrophobicContact CD1-CB 4.26Å; L245-N401 HydrophobicContact CD2-CB 4.01Å; N249-N401 PolarHBondContact ND2-OD1 3.39Å; A256-N401 PolarHBondContact O-ND2 3.39Å; Q260-N401 PolarHBondContact OE1-ND2 3.01Å; V397-N401 PolarHBondContact O-N 3.08Å; S399-N401 VanDerWaalsContact C-N 3.33Å; S399-N401 PolarHBondContact O-N 2.97Å; N401-V403 VanDerWaalsContact C-N 3.33Å; N401-V403 PolarHBondContact O-N 2.84Å; N401-I404 PolarHBondContact O-N 3.41Å; N401-L405 WeakPolarHBondContact O-CB 2.96Å; N401-L405 PolarHBondContact O-N 2.98Å
402	G	90	Very high	88.8	Confident	0 Å²	0	4.7 Å²	4.7	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-63.6	-35.2	176.3	0	0	0	0	0	113.7	C102 G398 S399 C400 T406	C102-G402 VanDerWaalsContact SG-CA 3.54Å; G398-G402 PolarHBondContact O-N 3.44Å; S399-G402 PolarHBondContact O-N 3.21Å; C400-G402 PolarHBondContact O-N 3.49Å; G402-T406 WeakPolarHBondContact O-CG2 3.4Å; G402-T406 PolarHBondContact O-N 2.9Å; G402-T406 PolarHBondContact O-OG1 2.55Å
403	V	87.6	Confident	88.6	Confident	5 Å²	5	5 Å²	5	3%	0.03	3%	0.033	C	C	.	.	H	α-helix	trans	-64.2	-49.6	171.9	174.6	0	0	0	0	110.8	A208 Y320 S399 C400 N401 L405 T406 A407	A208-V403 HydrophobicContact CB-CB 4.43Å; A208-V403 HydrophobicContact CB-CG1 3.86Å; Y320-V403 HydrophobicContact CE1-CG2 3.86Å; S399-V403 WeakPolarHBondContact O-CG2 3.27Å; S399-V403 PolarHBondContact O-N 2.93Å; C400-V403 PolarHBondContact O-N 3.35Å; N401-V403 VanDerWaalsContact C-N 3.33Å; N401-V403 PolarHBondContact O-N 2.84Å; V403-L405 VanDerWaalsContact C-N 3.3Å; V403-L405 PolarHBondContact O-N 3.38Å; V403-T406 PolarHBondContact O-N 2.78Å; V403-T406 PolarHBondContact O-OG1 2.84Å; V403-T406 VanDerWaalsContact O-OG1 3.13Å; V403-A407 WeakPolarHBondContact O-CB 3.18Å; V403-A407 PolarHBondContact O-N 3.25Å
404	I	88.5	Confident	88.2	Confident	0 Å²	0	4.9 Å²	4.9	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-59.7	-43.9	179.7	-68.1	165.7	0	0	0	110.7	A208 L242 L245 N249 C400 N401 T406 S408 I438	A208-I404 HydrophobicContact CB-CG1 4.39Å; L242-I404 HydrophobicContact CD2-CD1 4.26Å; L245-I404 HydrophobicContact CB-CD1 3.65Å; L245-I404 HydrophobicContact CD1-CD1 4.27Å; N249-I404 HydrophobicContact CB-CG2 4.18Å; C400-I404 WeakPolarHBondContact O-CG1 3.09Å; C400-I404 PolarHBondContact O-N 3.13Å; N401-I404 PolarHBondContact O-N 3.41Å; I404-T406 PolarHBondContact O-N 3.45Å; I404-S408 WeakPolarHBondContact O-CB 3.34Å; I404-S408 PolarHBondContact O-N 3.39Å; I404-S408 VanDerWaalsContact O-N 3.13Å; I404-S408 PolarHBondContact O-OG 3.09Å; I404-I438 HydrophobicContact CG2-CG2 4.22Å
405	L	88.7	Confident	87.6	Confident	0 Å²	0	2.3 Å²	2.3	0%	0	2%	0.015	C	C	.	.	H	α-helix	trans	-57.2	-50.6	177	-171.3	78.2	0	0	0	110.5	I98 N249 V253 A256 T257 I324 N401 V403 S408 R409	I98-L405 HydrophobicContact CD1-CD2 3.93Å; I98-L405 HydrophobicContact CG1-CD2 4.39Å; N249-L405 WeakPolarHBondContact OD1-CD1 3.35Å; V253-L405 HydrophobicContact CG1-CD1 4.32Å; A256-L405 HydrophobicContact CB-CD1 4.39Å; T257-L405 HydrophobicContact CG2-CD2 4.42Å; I324-L405 HydrophobicContact CD1-CD2 3.96Å; N401-L405 WeakPolarHBondContact O-CB 2.96Å; N401-L405 PolarHBondContact O-N 2.98Å; V403-L405 VanDerWaalsContact C-N 3.3Å; V403-L405 PolarHBondContact O-N 3.38Å; L405-S408 PolarHBondContact O-OG 2.9Å; L405-R409 WeakPolarHBondContact O-CD 3.32Å; L405-R409 PolarHBondContact O-NH1 3.2Å; L405-R409 VanDerWaalsContact O-NH1 3.1Å
406	T	88	Confident	87.1	Confident	0 Å²	0	8.6 Å²	8.6	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-78.4	-36.1	-175.7	55.6	0	0	0	0	113.7	R204 Y320 F323 I324 G402 V403 I404 R409 L410	R204-T406 VanDerWaalsContact NH2-C 3.27Å; R204-T406 PolarHBondContact NH2-O 3.15Å; Y320-T406 HydrophobicContact CD1-CG2 3.98Å; Y320-T406 HydrophobicContact CG-CG2 4.24Å; Y320-T406 WeakPolarHBondContact O-CG2 3.09Å; F323-T406 HydrophobicContact CB-CG2 4.43Å; I324-T406 HydrophobicContact CD1-CG2 4.36Å; I324-T406 HydrophobicContact CG2-CG2 4.16Å; G402-T406 WeakPolarHBondContact O-CG2 3.4Å; G402-T406 PolarHBondContact O-N 2.9Å; G402-T406 PolarHBondContact O-OG1 2.55Å; V403-T406 PolarHBondContact O-N 2.78Å; V403-T406 PolarHBondContact O-OG1 2.84Å; V403-T406 VanDerWaalsContact O-OG1 3.13Å; I404-T406 PolarHBondContact O-N 3.45Å; T406-R409 PolarHBondContact O-N 3.48Å; T406-L410 PolarHBondContact O-N 2.7Å
407	A	84.6	Confident	86.6	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-59.1	-49.7	175.8	0	0	0	0	0	112.5	R204 V403 R409 L410 F411 T441	R204-A407 HydrophobicContact CB-CB 3.9Å; R204-A407 HydrophobicContact CG-CB 4.04Å; R204-A407 VanDerWaalsContact NE-CA 3.33Å; R204-A407 VanDerWaalsContact NH2-CA 3.3Å; V403-A407 WeakPolarHBondContact O-CB 3.18Å; V403-A407 PolarHBondContact O-N 3.25Å; A407-R409 PolarHBondContact O-N 3.26Å; A407-L410 WeakPolarHBondContact O-CB 3.38Å; A407-L410 PolarHBondContact O-N 2.87Å; A407-F411 HydrophobicContact CB-CE2 4.03Å; A407-F411 WeakPolarHBondContact O-CD2 3.3Å; A407-F411 VanDerWaalsContact O-CE2 3.28Å; A407-F411 WeakPolarHBondContact O-CE2 3.25Å; A407-F411 PolarHBondContact O-N 3.32Å; A407-F411 VanDerWaalsContact O-N 3.16Å; A407-T441 HydrophobicContact CB-CG2 3.68Å
408	S	86.7	Confident	85.8	Confident	0 Å²	0	12 Å²	12	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-55.8	-37.3	177.7	53.1	0	0	0	0	112.8	I404 L405 F411 F412 A437 I438	I404-S408 WeakPolarHBondContact O-CB 3.34Å; I404-S408 PolarHBondContact O-N 3.39Å; I404-S408 VanDerWaalsContact O-N 3.13Å; I404-S408 PolarHBondContact O-OG 3.09Å; L405-S408 PolarHBondContact O-OG 2.9Å; S408-F411 PolarHBondContact O-N 3.25Å; S408-F412 WeakPolarHBondContact O-CB 3.29Å; S408-F412 PolarHBondContact O-N 2.91Å; S408-A437 WeakPolarHBondContact O-CB 3.25Å; S408-I438 VanDerWaalsContact CB-CG1 3.46Å
409	R	87.9	Confident	85.1	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-75.6	-29.1	178.7	-80	77.6	172.5	173.1	-12.9	113.4	L86 V253 I324 E327 L405 T406 A407 F411 A413	L86-R409 HydrophobicContact CD1-CG 4.32Å; V253-R409 VanDerWaalsContact CG2-NH2 3.33Å; I324-R409 HydrophobicContact CG2-CB 3.99Å; I324-R409 HydrophobicContact CG2-CG 3.88Å; E327-R409 IonicContact OE1-CZ 2.98Å; E327-R409 IonicContact OE1-NE 3.98Å; E327-R409 PolarHBondContact OE1-NE 3.38Å; E327-R409 IonicContact OE1-NH2 3.2Å; E327-R409 PolarHBondContact OE1-NH2 2.65Å; E327-R409 IonicContact OE2-CZ 2.95Å; E327-R409 IonicContact OE2-NE 2.71Å; E327-R409 IonicContact OE2-NH2 2.86Å; E327-R409 PolarHBondContact OE2-NH2 3.39Å; L405-R409 WeakPolarHBondContact O-CD 3.32Å; L405-R409 PolarHBondContact O-NH1 3.2Å; L405-R409 VanDerWaalsContact O-NH1 3.1Å; T406-R409 PolarHBondContact O-N 3.48Å; A407-R409 PolarHBondContact O-N 3.26Å; R409-F411 VanDerWaalsContact C-N 3.35Å; R409-A413 VanDerWaalsContact O-CB 3.28Å; R409-A413 WeakPolarHBondContact O-CB 3.27Å; R409-A413 PolarHBondContact O-N 2.98Å
410	L	86.2	Confident	84.2	Confident	0 Å²	0	13.6 Å²	13.6	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-61.1	-45.8	168.7	172.6	64.6	0	0	0	110.7	Y157 L173 E176 R204 F323 T406 A407 A413 G414	Y157-L410 HydrophobicContact CD1-CD1 4.12Å; Y157-L410 HydrophobicContact CG-CD1 3.81Å; L173-L410 HydrophobicContact CD1-CD1 3.7Å; L173-L410 HydrophobicContact CD1-CD2 4Å; L173-L410 HydrophobicContact CD1-CG 3.61Å; E176-L410 HydrophobicContact CB-CD2 4.08Å; E176-L410 HydrophobicContact CG-CD2 3.85Å; R204-L410 VanDerWaalsContact CZ-CD2 3.41Å; F323-L410 HydrophobicContact CD1-CB 4.07Å; F323-L410 HydrophobicContact CD1-CD1 4.4Å; F323-L410 HydrophobicContact CE1-CB 4.44Å; F323-L410 HydrophobicContact CE1-CD1 4.2Å; F323-L410 HydrophobicContact CE1-CD2 4.44Å; T406-L410 PolarHBondContact O-N 2.7Å; A407-L410 WeakPolarHBondContact O-CB 3.38Å; A407-L410 PolarHBondContact O-N 2.87Å; L410-A413 PolarHBondContact O-N 3.47Å; L410-G414 PolarHBondContact O-N 3.44Å
411	F	82.8	Confident	83.3	Confident	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-70.6	-39.7	-179.8	-54.6	-42.9	0	0	0	113.3	L173 F203 R204 A407 S408 R409 A413 G414 A415 L424 A437 T441	L173-F411 HydrophobicContact CD1-CD1 4.2Å; L173-F411 HydrophobicContact CD1-CE1 4.4Å; F203-F411 VanDerWaalsContact C-CE2 3.43Å; F203-F411 VanDerWaalsContact CA-CZ 3.4Å; F203-F411 HydrophobicContact CB-CD1 4.03Å; F203-F411 HydrophobicContact CB-CD2 3.7Å; F203-F411 HydrophobicContact CB-CE1 3.76Å; F203-F411 HydrophobicContact CB-CE2 3.4Å; F203-F411 VanDerWaalsContact CB-CE2 3.4Å; F203-F411 HydrophobicContact CB-CG 4.02Å; F203-F411 HydrophobicContact CB-CZ 3.45Å; F203-F411 VanDerWaalsContact CB-CZ 3.45Å; F203-F411 HydrophobicContact CD1-CB 4.29Å; F203-F411 AromaticContact CD1-CD1 3.15Å; F203-F411 HydrophobicContact CD1-CD1 3.15Å; F203-F411 HydrophobicContact CD1-CD2 4.14Å; F203-F411 AromaticContact CD1-CE1 3.46Å; F203-F411 HydrophobicContact CD1-CE1 3.46Å; F203-F411 VanDerWaalsContact CD1-CE1 3.46Å; F203-F411 HydrophobicContact CD1-CE2 4.39Å; F203-F411 AromaticContact CD1-CG 3.56Å; F203-F411 HydrophobicContact CD1-CG 3.56Å; F203-F411 HydrophobicContact CD1-CZ 4.08Å; F203-F411 HydrophobicContact CE1-CB 4.47Å; F203-F411 AromaticContact CE1-CD1 3.81Å; F203-F411 HydrophobicContact CE1-CD1 3.81Å; F203-F411 HydrophobicContact CE1-CE1 4.45Å; F203-F411 HydrophobicContact CE1-CG 4.17Å; F203-F411 AromaticContact CG-CD1 3.96Å; F203-F411 HydrophobicContact CG-CD1 3.96Å; F203-F411 HydrophobicContact CG-CD2 4.16Å; F203-F411 HydrophobicContact CG-CE1 4.09Å; F203-F411 HydrophobicContact CG-CE2 4.29Å; F203-F411 HydrophobicContact CG-CG 4.02Å; F203-F411 HydrophobicContact CG-CZ 4.26Å; R204-F411 HydrophobicContact CB-CE1 4.33Å; R204-F411 HydrophobicContact CB-CE2 4.01Å; R204-F411 HydrophobicContact CB-CZ 3.35Å; A407-F411 HydrophobicContact CB-CE2 4.03Å; A407-F411 WeakPolarHBondContact O-CD2 3.3Å; A407-F411 VanDerWaalsContact O-CE2 3.28Å; A407-F411 WeakPolarHBondContact O-CE2 3.25Å; A407-F411 PolarHBondContact O-N 3.32Å; A407-F411 VanDerWaalsContact O-N 3.16Å; S408-F411 PolarHBondContact O-N 3.25Å; R409-F411 VanDerWaalsContact C-N 3.35Å; F411-A413 VanDerWaalsContact C-N 3.28Å; F411-A413 PolarHBondContact O-N 2.93Å; F411-G414 PolarHBondContact O-N 3.39Å; F411-A415 VanDerWaalsContact O-CB 3.26Å; F411-A415 WeakPolarHBondContact O-CB 3.43Å; F411-A415 PolarHBondContact O-N 2.62Å; F411-L424 HydrophobicContact CB-CD1 4.22Å; F411-A437 HydrophobicContact CB-CB 4.3Å; F411-T441 WeakPolarHBondContact CD2-OG1 3.11Å; F411-T441 WeakPolarHBondContact CE2-OG1 3.47Å
412	F	84.2	Confident	82.3	Confident	6 Å²	6	18.8 Å²	18.8	3%	0.026	9%	0.092	C	C	.	.	H	α-helix	trans	-55.2	-46.4	171	177.2	-99.9	0	0	0	111.2	L86 S408 A415 R416 L424 T425 I427 P434 A437	L86-F412 HydrophobicContact CD1-CD1 4.02Å; L86-F412 HydrophobicContact CD1-CE1 3.79Å; L86-F412 HydrophobicContact CG-CE1 4.17Å; S408-F412 WeakPolarHBondContact O-CB 3.29Å; S408-F412 PolarHBondContact O-N 2.91Å; F412-A415 PolarHBondContact O-N 3.38Å; F412-R416 HydrophobicContact CE1-CG 4.37Å; F412-R416 HydrophobicContact CZ-CG 4.34Å; F412-R416 WeakPolarHBondContact O-CG 3.37Å; F412-R416 PolarHBondContact O-N 2.93Å; F412-L424 WeakPolarHBondContact CD2-O 3.27Å; F412-T425 VanDerWaalsContact CE2-O 3.31Å; F412-T425 WeakPolarHBondContact CE2-O 3.36Å; F412-I427 HydrophobicContact CE2-CD1 3.92Å; F412-I427 HydrophobicContact CE2-CG1 3.65Å; F412-I427 HydrophobicContact CZ-CD1 3.78Å; F412-I427 HydrophobicContact CZ-CG1 4.06Å; F412-P434 HydrophobicContact CB-CB 4.32Å; F412-P434 HydrophobicContact CD2-CB 3.88Å; F412-P434 HydrophobicContact CG-CB 4.25Å; F412-A437 HydrophobicContact CB-CB 4.5Å
413	A	84.6	Confident	81.4	Confident	7 Å²	7	23 Å²	23	6%	0.058	11%	0.112	C	C	.	.	H	α-helix	trans	-66.4	-42.5	176.4	0	0	0	0	0	112.9	S153 Y157 R409 L410 F411 A415 R416 E417	S153-A413 WeakPolarHBondContact O-CB 3.29Å; Y157-A413 HydrophobicContact CD1-CB 4.37Å; Y157-A413 HydrophobicContact CE1-CB 4.36Å; R409-A413 VanDerWaalsContact O-CB 3.28Å; R409-A413 WeakPolarHBondContact O-CB 3.27Å; R409-A413 PolarHBondContact O-N 2.98Å; L410-A413 PolarHBondContact O-N 3.47Å; F411-A413 VanDerWaalsContact C-N 3.28Å; F411-A413 PolarHBondContact O-N 2.93Å; A413-A415 VanDerWaalsContact C-N 3.32Å; A413-A415 PolarHBondContact O-N 2.93Å; A413-R416 PolarHBondContact O-N 2.81Å; A413-E417 PolarHBondContact O-N 3.47Å
414	G	81.5	Confident	80.8	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-59.1	-42.6	175	0	0	0	0	0	112.7	L410 F411 E417 G418 H419 M420	L410-G414 PolarHBondContact O-N 3.44Å; F411-G414 PolarHBondContact O-N 3.39Å; G414-E417 PolarHBondContact O-N 3.43Å; G414-G418 PolarHBondContact O-N 3.02Å; G414-H419 WeakPolarHBondContact O-CB 3.49Å; G414-H419 PolarHBondContact O-N 2.88Å; G414-M420 PolarHBondContact O-N 3.17Å
415	A	79.2	Confident	80.3	Confident	3 Å²	3	25.3 Å²	25.3	3%	0.025	13%	0.126	C	C	.	.	H	α-helix	trans	-70.2	-35.1	178.4	0	0	0	0	0	112.2	F411 F412 A413 E417 G418 M420 P421 L424 T425	F411-A415 VanDerWaalsContact O-CB 3.26Å; F411-A415 WeakPolarHBondContact O-CB 3.43Å; F411-A415 PolarHBondContact O-N 2.62Å; F412-A415 PolarHBondContact O-N 3.38Å; A413-A415 VanDerWaalsContact C-N 3.32Å; A413-A415 PolarHBondContact O-N 2.93Å; A415-E417 VanDerWaalsContact C-N 3.3Å; A415-E417 PolarHBondContact O-N 3.17Å; A415-G418 WeakPolarHBondContact O-CA 3.33Å; A415-G418 PolarHBondContact O-N 3.45Å; A415-M420 HydrophobicContact CB-CB 3.96Å; A415-P421 WeakPolarHBondContact CB-O 3.28Å; A415-L424 HydrophobicContact CB-CB 3.73Å; A415-T425 HydrophobicContact CB-CG2 3.4Å; A415-T425 VanDerWaalsContact CB-CG2 3.4Å; A415-T425 WeakPolarHBondContact O-CG2 3.41Å
416	R	80.5	Confident	79.8	Confident	131 Å²	131	28.9 Å²	28.9	49%	0.494	15%	0.145	S	C	.	.	H	α-helix	trans	-62.7	-36.3	175.5	-79.8	178	66.1	-170	2	112.8	E326 F412 A413 G418 T425	E326-R416 IonicContact OE1-NH1 3.24Å; E326-R416 PolarHBondContact OE1-NH1 3.46Å; E326-R416 IonicContact OE2-NH1 2.79Å; E326-R416 PolarHBondContact OE2-NH1 2.82Å; F412-R416 HydrophobicContact CE1-CG 4.37Å; F412-R416 HydrophobicContact CZ-CG 4.34Å; F412-R416 WeakPolarHBondContact O-CG 3.37Å; F412-R416 PolarHBondContact O-N 2.93Å; A413-R416 PolarHBondContact O-N 2.81Å; R416-G418 PolarHBondContact O-N 3.25Å; R416-T425 HydrophobicContact CB-CG2 4.41Å; R416-T425 HydrophobicContact CG-CG2 3.88Å; R416-T425 VanDerWaalsContact N-CG2 3.3Å
417	E	79.6	Confident	79.4	Confident	84 Å²	84	30.4 Å²	30.4	39%	0.393	15%	0.153	S	C	.	.	T	Hydrogen-bonded Turn	trans	-82.6	3.4	174.7	-60.6	-68.1	158.3	0	0	112	K152 Y157 A413 G414 A415 H419	K152-E417 IonicContact NZ-OE1 2.95Å; K152-E417 PolarHBondContact NZ-OE1 3.27Å; Y157-E417 HydrophobicContact CE1-CG 4.2Å; Y157-E417 WeakPolarHBondContact OH-CB 3.44Å; Y157-E417 WeakPolarHBondContact OH-CG 3.36Å; A413-E417 PolarHBondContact O-N 3.47Å; G414-E417 PolarHBondContact O-N 3.43Å; A415-E417 VanDerWaalsContact C-N 3.3Å; A415-E417 PolarHBondContact O-N 3.17Å; E417-H419 VanDerWaalsContact C-N 3.27Å; E417-H419 PolarHBondContact O-N 3.28Å
418	G	74.6	Confident	79	Confident	12 Å²	12	31.6 Å²	31.6	12%	0.124	16%	0.161	C	C	.	.	T	Hydrogen-bonded Turn	trans	72.8	18.3	176.8	0	0	0	0	0	114.4	G414 A415 R416 R541	G414-G418 PolarHBondContact O-N 3.02Å; A415-G418 WeakPolarHBondContact O-CA 3.33Å; A415-G418 PolarHBondContact O-N 3.45Å; R416-G418 PolarHBondContact O-N 3.25Å; G418-R541 PolarHBondContact O-NH2 3.42Å
419	H	78	Confident	78.2	Confident	12 Å²	12	38.9 Å²	38.9	6%	0.056	20%	0.198	C	C	.	.	S	Bend	trans	-87.7	-9.1	175.2	-71.5	166.1	0	0	0	112.9	Y157 P166 F170 L173 G414 E417 I538	Y157-H419 AromaticContact CE2-ND1 3.56Å; Y157-H419 AromaticContact CZ-ND1 3.57Å; Y157-H419 PolarHBondContact OH-CE1 2.95Å; Y157-H419 PolarHBondContact OH-ND1 2.74Å; P166-H419 WeakPolarHBondContact CB-NE2 3.43Å; P166-H419 PolarHBondContact O-CE1 3.25Å; F170-H419 HydrophobicContact CD2-CB 3.97Å; F170-H419 WeakPolarHBondContact CE2-O 3.22Å; L173-H419 HydrophobicContact CD2-CB 3.78Å; G414-H419 WeakPolarHBondContact O-CB 3.49Å; G414-H419 PolarHBondContact O-N 2.88Å; E417-H419 VanDerWaalsContact C-N 3.27Å; E417-H419 PolarHBondContact O-N 3.28Å; H419-I538 HydrophobicContact CB-CD1 4.34Å
420	M	72.7	Confident	77.6	Confident	26 Å²	26	45.4 Å²	45.4	13%	0.128	23%	0.233	C	C	.	.	S	Bend	trans	-138.8	166.9	178.6	-72.1	-62	-166.5	0	0	111.1	L173 A177 F203 G414 A415 Q422 L424	L173-M420 HydrophobicContact CD2-CE 3.79Å; L173-M420 HydrophobicContact CD2-CG 3.44Å; L173-M420 VanDerWaalsContact CD2-CG 3.44Å; L173-M420 HydrophobicContact CD2-SD 4.35Å; L173-M420 HydrophobicContact CG-CE 3.67Å; L173-M420 HydrophobicContact CG-CG 4.27Å; A177-M420 HydrophobicContact CB-CE 3.96Å; F203-M420 HydrophobicContact CD1-CE 3.87Å; F203-M420 HydrophobicContact CD1-SD 4.29Å; F203-M420 HydrophobicContact CE1-CB 4.17Å; F203-M420 HydrophobicContact CE1-CE 3.32Å; F203-M420 HydrophobicContact CE1-CG 3.61Å; F203-M420 HydrophobicContact CE1-SD 3.18Å; F203-M420 WeakPolarHBondContact CE1-SD 3.16Å; F203-M420 HydrophobicContact CZ-CB 4.33Å; F203-M420 HydrophobicContact CZ-CE 4.14Å; F203-M420 HydrophobicContact CZ-CG 4.16Å; F203-M420 HydrophobicContact CZ-SD 3.51Å; F203-M420 VanDerWaalsContact CZ-SD 3.51Å; G414-M420 PolarHBondContact O-N 3.17Å; A415-M420 HydrophobicContact CB-CB 3.96Å; M420-Q422 PolarHBondContact O-N 3.35Å; M420-L424 HydrophobicContact CB-CD1 4.38Å
421	P	71.1	Confident	77	Confident	47 Å²	47	50.2 Å²	50.2	31%	0.305	25%	0.254	S	S	.	.			trans	-54.9	133.3	179.2	-25.9	35.6	0	0	0	112.1	A415 M423 L424	A415-P421 WeakPolarHBondContact CB-O 3.28Å; P421-M423 PolarHBondContact O-N 2.68Å; P421-M423 VanDerWaalsContact O-N 3.11Å; P421-L424 WeakPolarHBondContact O-CB 3.14Å; P421-L424 PolarHBondContact O-N 3.01Å
422	Q	71.4	Confident	76.7	Confident	62 Å²	62	53.9 Å²	53.9	29%	0.29	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-62.2	-21.6	-175.5	-72.3	-177.1	-12.6	0	0	113.8	M420 L424 T425 S549	M420-Q422 PolarHBondContact O-N 3.35Å; Q422-L424 PolarHBondContact O-N 3.17Å; Q422-L424 VanDerWaalsContact O-N 3.11Å; Q422-T425 PolarHBondContact O-N 2.96Å; Q422-T425 PolarHBondContact O-OG1 2.92Å; Q422-S549 PolarHBondContact NE2-OG 3.48Å; Q422-S549 PolarHBondContact OE1-OG 3.41Å
423	M	71.5	Confident	76.6	Confident	88 Å²	88	53.6 Å²	53.6	43%	0.433	27%	0.272	S	S	.	.	G	3₁₀ helix	trans	-57.2	-28	174.2	-65	176.5	177.2	0	0	112.2	P421 T425 L426 P436	P421-M423 PolarHBondContact O-N 2.68Å; P421-M423 VanDerWaalsContact O-N 3.11Å; M423-T425 PolarHBondContact O-N 2.74Å; M423-L426 HydrophobicContact CB-CD1 4.45Å; M423-L426 WeakPolarHBondContact O-CB 3.31Å; M423-L426 VanDerWaalsContact O-CG 3.32Å; M423-L426 WeakPolarHBondContact O-CG 3.38Å; M423-L426 PolarHBondContact O-N 2.93Å; M423-P436 WeakPolarHBondContact O-CB 3.47Å
424	L	74.9	Confident	76.6	Confident	9 Å²	9	53.2 Å²	53.2	5%	0.047	27%	0.269	C	S	.	.	G	3₁₀ helix	trans	-77.5	-8	178.4	-52.8	-179.2	0	0	0	113.3	F203 F411 F412 A415 M420 P421 Q422 L426 P436 A437 A440	F203-L424 HydrophobicContact CD2-CD1 4.31Å; F203-L424 HydrophobicContact CE1-CD1 3.72Å; F203-L424 HydrophobicContact CE2-CD1 3.63Å; F203-L424 HydrophobicContact CZ-CD1 3.29Å; F411-L424 HydrophobicContact CB-CD1 4.22Å; F412-L424 WeakPolarHBondContact CD2-O 3.27Å; A415-L424 HydrophobicContact CB-CB 3.73Å; M420-L424 HydrophobicContact CB-CD1 4.38Å; P421-L424 WeakPolarHBondContact O-CB 3.14Å; P421-L424 PolarHBondContact O-N 3.01Å; Q422-L424 PolarHBondContact O-N 3.17Å; Q422-L424 VanDerWaalsContact O-N 3.11Å; L424-L426 VanDerWaalsContact C-N 3.32Å; L424-P436 HydrophobicContact CD2-CB 4.23Å; L424-A437 HydrophobicContact CB-CB 4.44Å; L424-A440 HydrophobicContact CD2-CB 3.97Å
425	T	77.1	Confident	76.8	Confident	44 Å²	44	54.7 Å²	54.7	27%	0.27	28%	0.278	S	S	.	.	G	3₁₀ helix	trans	-85.2	-6.7	169.3	69	0	0	0	0	112.9	F412 A415 R416 Q422 M423	F412-T425 VanDerWaalsContact CE2-O 3.31Å; F412-T425 WeakPolarHBondContact CE2-O 3.36Å; A415-T425 HydrophobicContact CB-CG2 3.4Å; A415-T425 VanDerWaalsContact CB-CG2 3.4Å; A415-T425 WeakPolarHBondContact O-CG2 3.41Å; R416-T425 HydrophobicContact CB-CG2 4.41Å; R416-T425 HydrophobicContact CG-CG2 3.88Å; R416-T425 VanDerWaalsContact N-CG2 3.3Å; Q422-T425 PolarHBondContact O-N 2.96Å; Q422-T425 PolarHBondContact O-OG1 2.92Å; M423-T425 PolarHBondContact O-N 2.74Å
426	L	78.7	Confident	77.1	Confident	76 Å²	76	56.5 Å²	56.5	40%	0.398	29%	0.29	S	S	.	.			trans	-73.2	135.9	-179.6	-60.1	171.5	0	0	0	109.8	M423 L424 P436	M423-L426 HydrophobicContact CB-CD1 4.45Å; M423-L426 WeakPolarHBondContact O-CB 3.31Å; M423-L426 VanDerWaalsContact O-CG 3.32Å; M423-L426 WeakPolarHBondContact O-CG 3.38Å; M423-L426 PolarHBondContact O-N 2.93Å; L424-L426 VanDerWaalsContact C-N 3.32Å; L426-P436 HydrophobicContact CB-CG 4.13Å; L426-P436 WeakPolarHBondContact O-CD 3.29Å
427	I	79.2	Confident	77.2	Confident	32 Å²	32	50.2 Å²	50.2	16%	0.164	27%	0.266	C	S	.	.			trans	-110.3	135.8	174.4	-60.2	174.1	0	0	0	106.6	V84 L86 F412 I429 L432 T433	V84-I427 HydrophobicContact CB-CD1 4.26Å; V84-I427 HydrophobicContact CG1-CB 4.31Å; V84-I427 HydrophobicContact CG1-CD1 3.75Å; V84-I427 HydrophobicContact CG1-CG2 4.27Å; L86-I427 HydrophobicContact CD2-CD1 4.42Å; F412-I427 HydrophobicContact CE2-CD1 3.92Å; F412-I427 HydrophobicContact CE2-CG1 3.65Å; F412-I427 HydrophobicContact CZ-CD1 3.78Å; F412-I427 HydrophobicContact CZ-CG1 4.06Å; I427-I429 PolarHBondContact O-N 3.42Å; I427-L432 VanDerWaalsContact CG2-C 3.43Å; I427-T433 WeakPolarHBondContact CA-O 3.48Å
428	S	77.8	Confident	77.5	Confident	24 Å²	24	46.2 Å²	46.2	17%	0.168	25%	0.247	C	C	.	.			trans	-60.8	133	172.4	168.2	0	0	0	0	110.2	D430 F431 L432 T433 T435	S428-D430 PolarHBondContact OG-N 3.1Å; S428-F431 WeakPolarHBondContact OG-CD2 3.4Å; S428-F431 PolarHBondContact OG-N 2.79Å; S428-L432 WeakPolarHBondContact O-CA 3.32Å; S428-L432 PolarHBondContact O-N 2.65Å; S428-T433 PolarHBondContact N-O 3.48Å; S428-T435 VanDerWaalsContact CB-OG1 3.22Å; S428-T435 WeakPolarHBondContact CB-OG1 3.29Å
429	I	68.8	Low	78.1	Confident	154 Å²	154	49.4 Å²	49.4	79%	0.79	26%	0.261	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.1	-41.2	-178.4	-58.4	172.7	0	0	0	110	I427	I427-I429 PolarHBondContact O-N 3.42Å
430	D	75	Confident	78.2	Confident	137 Å²	137	49.2 Å²	49.2	73%	0.733	26%	0.261	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.9	-38.3	-174.1	-56.2	-44.4	0	0	0	112.5	S428	S428-D430 PolarHBondContact OG-N 3.1Å
431	F	74.3	Confident	78.5	Confident	101 Å²	101	48 Å²	48	44%	0.443	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.3	-10.6	-172.4	-55.1	-58.5	0	0	0	113.9	W251 S428 T433	W251-F431 AromaticContact CD1-CD1 3.87Å; W251-F431 AromaticContact CD1-CE1 3.55Å; W251-F431 AromaticContact NE1-CE1 3.97Å; W251-F431 WeakPolarHBondContact O-CB 3.39Å; W251-F431 WeakPolarHBondContact O-CD1 3.27Å; W251-F431 WeakPolarHBondContact O-CG 3.25Å; S428-F431 WeakPolarHBondContact OG-CD2 3.4Å; S428-F431 PolarHBondContact OG-N 2.79Å; F431-T433 HydrophobicContact CB-CG2 4.12Å; F431-T433 WeakPolarHBondContact O-CG2 3.22Å; F431-T433 PolarHBondContact O-N 3.34Å; F431-T433 VanDerWaalsContact O-N 3.09Å
432	L	75.5	Confident	79	Confident	76 Å²	76	45.9 Å²	45.9	40%	0.398	24%	0.242	S	C	.	.			trans	54.4	24.5	-175.6	-57	174.8	0	0	0	113.7	I427 S428	I427-L432 VanDerWaalsContact CG2-C 3.43Å; S428-L432 WeakPolarHBondContact O-CA 3.32Å; S428-L432 PolarHBondContact O-N 2.65Å
433	T	83.7	Confident	79.5	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	25%	0.251	C	S	.	.	S	Bend	trans	-100.8	147.3	179.6	58.7	0	0	0	0	110.2	C250 V253 I427 S428 F431 T435	C250-T433 PolarHBondContact O-OG1 3.36Å; V253-T433 HydrophobicContact CG2-CG2 3.52Å; I427-T433 WeakPolarHBondContact CA-O 3.48Å; S428-T433 PolarHBondContact N-O 3.48Å; F431-T433 HydrophobicContact CB-CG2 4.12Å; F431-T433 WeakPolarHBondContact O-CG2 3.22Å; F431-T433 PolarHBondContact O-N 3.34Å; F431-T433 VanDerWaalsContact O-N 3.09Å; T433-T435 PolarHBondContact O-N 3.45Å; T433-T435 PolarHBondContact O-OG1 3.06Å; T433-T435 PolarHBondContact OG1-OG1 3.48Å; T433-T435 VanDerWaalsContact OG1-OG1 3.07Å
434	P	84	Confident	79.6	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	23%	0.231	C	C	.	.			trans	-76.2	65.1	173.4	32.5	-35.5	0	0	0	110.6	F412 A437 I438	F412-P434 HydrophobicContact CB-CB 4.32Å; F412-P434 HydrophobicContact CD2-CB 3.88Å; F412-P434 HydrophobicContact CG-CB 4.25Å; P434-A437 HydrophobicContact CB-CB 4.24Å; P434-A437 WeakPolarHBondContact O-CB 3.36Å; P434-A437 PolarHBondContact O-N 2.82Å; P434-I438 HydrophobicContact CG-CD1 4.14Å; P434-I438 HydrophobicContact CG-CG1 4.32Å; P434-I438 WeakPolarHBondContact O-CG1 3.33Å; P434-I438 PolarHBondContact O-N 2.91Å
435	T	86.1	Confident	79.7	Confident	30 Å²	30	42.8 Å²	42.8	18%	0.184	23%	0.229	C	C	.	.	H	α-helix	trans	-53.8	-44.9	-169.8	-45.6	0	0	0	0	113.4	C250 S428 T433 A437 I438 L439	C250-T435 HydrophobicContact CB-CG2 3.97Å; S428-T435 VanDerWaalsContact CB-OG1 3.22Å; S428-T435 WeakPolarHBondContact CB-OG1 3.29Å; T433-T435 PolarHBondContact O-N 3.45Å; T433-T435 PolarHBondContact O-OG1 3.06Å; T433-T435 PolarHBondContact OG1-OG1 3.48Å; T433-T435 VanDerWaalsContact OG1-OG1 3.07Å; T435-A437 VanDerWaalsContact C-N 3.32Å; T435-A437 PolarHBondContact O-N 3.28Å; T435-I438 PolarHBondContact O-N 2.73Å; T435-L439 HydrophobicContact CG2-CD1 4.01Å; T435-L439 HydrophobicContact CG2-CG 4.21Å; T435-L439 WeakPolarHBondContact O-CB 3.28Å; T435-L439 WeakPolarHBondContact O-CG 3.16Å; T435-L439 PolarHBondContact O-N 3.44Å
436	P	84	Confident	79.7	Confident	41 Å²	41	41.5 Å²	41.5	27%	0.266	22%	0.221	S	C	.	.	H	α-helix	trans	-64.9	-34.9	178.8	-25.8	39.4	0	0	0	113.2	M423 L424 L426 A440	M423-P436 WeakPolarHBondContact O-CB 3.47Å; L424-P436 HydrophobicContact CD2-CB 4.23Å; L426-P436 HydrophobicContact CB-CG 4.13Å; L426-P436 WeakPolarHBondContact O-CD 3.29Å; P436-A440 WeakPolarHBondContact O-CB 3.23Å; P436-A440 PolarHBondContact O-N 3.07Å
437	A	83.3	Confident	79.2	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-68.8	-36.8	174.9	0	0	0	0	0	112.2	S408 F411 F412 L424 P434 T435 T441	S408-A437 WeakPolarHBondContact O-CB 3.25Å; F411-A437 HydrophobicContact CB-CB 4.3Å; F412-A437 HydrophobicContact CB-CB 4.5Å; L424-A437 HydrophobicContact CB-CB 4.44Å; P434-A437 HydrophobicContact CB-CB 4.24Å; P434-A437 WeakPolarHBondContact O-CB 3.36Å; P434-A437 PolarHBondContact O-N 2.82Å; T435-A437 VanDerWaalsContact C-N 3.32Å; T435-A437 PolarHBondContact O-N 3.28Å; A437-T441 WeakPolarHBondContact O-CB 3.4Å; A437-T441 PolarHBondContact O-N 3.25Å; A437-T441 PolarHBondContact O-OG1 3.44Å
438	I	86.7	Confident	78.8	Confident	0 Å²	0	41 Å²	41	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-68	-49.7	175.6	-62.4	163.6	0	0	0	110.3	T246 N249 C250 I404 S408 P434 T435 A440 T441 G442	T246-I438 HydrophobicContact CG2-CG2 3.87Å; N249-I438 HydrophobicContact CB-CD1 4.29Å; N249-I438 HydrophobicContact CB-CG2 3.73Å; N249-I438 WeakPolarHBondContact O-CD1 3.46Å; C250-I438 WeakPolarHBondContact SG-CG2 3.19Å; I404-I438 HydrophobicContact CG2-CG2 4.22Å; S408-I438 VanDerWaalsContact CB-CG1 3.46Å; P434-I438 HydrophobicContact CG-CD1 4.14Å; P434-I438 HydrophobicContact CG-CG1 4.32Å; P434-I438 WeakPolarHBondContact O-CG1 3.33Å; P434-I438 PolarHBondContact O-N 2.91Å; T435-I438 PolarHBondContact O-N 2.73Å; I438-A440 VanDerWaalsContact C-N 3.33Å; I438-A440 PolarHBondContact O-N 2.97Å; I438-T441 WeakPolarHBondContact O-CB 3.5Å; I438-T441 PolarHBondContact O-N 3.18Å; I438-T441 VanDerWaalsContact O-N 3.15Å; I438-G442 PolarHBondContact O-N 3.3Å
439	L	87.1	Confident	78.4	Confident	78 Å²	78	40.3 Å²	40.3	41%	0.408	21%	0.213	S	C	.	.	H	α-helix	trans	-59.8	-43.4	177	-70.9	176.7	0	0	0	111.6	T246 T435 T441 G442 I443	T246-L439 HydrophobicContact CG2-CD2 4.14Å; T435-L439 HydrophobicContact CG2-CD1 4.01Å; T435-L439 HydrophobicContact CG2-CG 4.21Å; T435-L439 WeakPolarHBondContact O-CB 3.28Å; T435-L439 WeakPolarHBondContact O-CG 3.16Å; T435-L439 PolarHBondContact O-N 3.44Å; L439-T441 PolarHBondContact O-N 2.7Å; L439-G442 PolarHBondContact O-N 3.37Å; L439-I443 HydrophobicContact CB-CD1 4.45Å; L439-I443 WeakPolarHBondContact O-CB 3.27Å; L439-I443 VanDerWaalsContact O-CG1 3.24Å; L439-I443 WeakPolarHBondContact O-CG1 3.29Å; L439-I443 PolarHBondContact O-N 3.36Å
440	A	78.3	Confident	78.1	Confident	8 Å²	8	37.1 Å²	37.1	7%	0.066	21%	0.21	C	C	.	.	H	α-helix	trans	-57	-51.2	173.6	0	0	0	0	0	110.4	F203 L424 P436 I438 G442 L444	F203-A440 HydrophobicContact CD2-CB 4.17Å; L424-A440 HydrophobicContact CD2-CB 3.97Å; P436-A440 WeakPolarHBondContact O-CB 3.23Å; P436-A440 PolarHBondContact O-N 3.07Å; I438-A440 VanDerWaalsContact C-N 3.33Å; I438-A440 PolarHBondContact O-N 2.97Å; A440-G442 VanDerWaalsContact C-N 3.31Å; A440-G442 PolarHBondContact O-N 3.08Å; A440-L444 HydrophobicContact CB-CD1 4.46Å; A440-L444 WeakPolarHBondContact O-CB 3.19Å; A440-L444 WeakPolarHBondContact O-CD1 3.21Å; A440-L444 WeakPolarHBondContact O-CG 3.27Å; A440-L444 PolarHBondContact O-N 3.19Å
441	T	81	Confident	77.4	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-55.5	-45.6	177.8	-53.2	0	0	0	0	111.9	A407 F411 A437 I438 L439 S445	A407-T441 HydrophobicContact CB-CG2 3.68Å; F411-T441 WeakPolarHBondContact CD2-OG1 3.11Å; F411-T441 WeakPolarHBondContact CE2-OG1 3.47Å; A437-T441 WeakPolarHBondContact O-CB 3.4Å; A437-T441 PolarHBondContact O-N 3.25Å; A437-T441 PolarHBondContact O-OG1 3.44Å; I438-T441 WeakPolarHBondContact O-CB 3.5Å; I438-T441 PolarHBondContact O-N 3.18Å; I438-T441 VanDerWaalsContact O-N 3.15Å; L439-T441 PolarHBondContact O-N 2.7Å; T441-S445 WeakPolarHBondContact O-CB 3.07Å; T441-S445 PolarHBondContact O-N 3Å; T441-S445 PolarHBondContact O-OG 3.32Å
442	G	81.1	Confident	76.5	Confident	3 Å²	3	33 Å²	33	3%	0.031	19%	0.194	C	C	.	.	H	α-helix	trans	-68.9	-53.1	-178.3	0	0	0	0	0	113.8	T246 I438 L439 A440 L444 S445 C446	T246-G442 WeakPolarHBondContact OG1-CA 3.47Å; I438-G442 PolarHBondContact O-N 3.3Å; L439-G442 PolarHBondContact O-N 3.37Å; A440-G442 VanDerWaalsContact C-N 3.31Å; A440-G442 PolarHBondContact O-N 3.08Å; G442-L444 PolarHBondContact O-N 3.41Å; G442-S445 WeakPolarHBondContact O-CB 3.47Å; G442-S445 PolarHBondContact O-N 2.85Å; G442-S445 VanDerWaalsContact O-N 3.17Å; G442-C446 PolarHBondContact O-N 3.2Å; G442-C446 PolarHBondContact O-SG 2.91Å
443	I	80.8	Confident	75.6	Confident	93 Å²	93	37.2 Å²	37.2	48%	0.477	21%	0.212	S	C	.	.	H	α-helix	trans	-55.4	-41.2	177.5	-69.2	167.2	0	0	0	110	L439 C446 L447	L439-I443 HydrophobicContact CB-CD1 4.45Å; L439-I443 WeakPolarHBondContact O-CB 3.27Å; L439-I443 VanDerWaalsContact O-CG1 3.24Å; L439-I443 WeakPolarHBondContact O-CG1 3.29Å; L439-I443 PolarHBondContact O-N 3.36Å; I443-C446 WeakPolarHBondContact O-CB 3.43Å; I443-C446 PolarHBondContact O-N 3.15Å; I443-L447 HydrophobicContact CG2-CD1 4.22Å; I443-L447 WeakPolarHBondContact O-CG 3.38Å; I443-L447 PolarHBondContact O-N 2.64Å
444	L	73.3	Confident	74.1	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-69.5	-45.9	-179.4	-67.5	168.9	0	0	0	111.6	F201 N202 F203 P205 A440 G442 C446 L447 F448	F201-L444 VanDerWaalsContact C-CD2 3.49Å; F201-L444 HydrophobicContact CB-CD1 4.26Å; F201-L444 HydrophobicContact CB-CD2 3.88Å; F201-L444 WeakPolarHBondContact O-CD2 3.33Å; N202-L444 VanDerWaalsContact CA-CD1 3.48Å; F203-L444 HydrophobicContact CB-CD1 3.55Å; F203-L444 HydrophobicContact CD2-CD1 3.51Å; F203-L444 HydrophobicContact CG-CD1 3.97Å; P205-L444 HydrophobicContact CB-CB 3.97Å; P205-L444 HydrophobicContact CG-CB 4.24Å; A440-L444 HydrophobicContact CB-CD1 4.46Å; A440-L444 WeakPolarHBondContact O-CB 3.19Å; A440-L444 WeakPolarHBondContact O-CD1 3.21Å; A440-L444 WeakPolarHBondContact O-CG 3.27Å; A440-L444 PolarHBondContact O-N 3.19Å; G442-L444 PolarHBondContact O-N 3.41Å; L444-C446 PolarHBondContact O-N 2.74Å; L444-C446 VanDerWaalsContact O-N 3.14Å; L444-L447 HydrophobicContact CD2-CD1 4.11Å; L444-L447 PolarHBondContact O-N 2.93Å; L444-F448 WeakPolarHBondContact O-CD2 3.15Å; L444-F448 PolarHBondContact O-N 3.36Å
445	S	77	Confident	72.6	Confident	0 Å²	0	43 Å²	43	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-51.7	-40	173.2	-55.4	0	0	0	0	111.6	P205 T209 T441 G442 F448 L449	P205-S445 WeakPolarHBondContact CA-OG 3.5Å; P205-S445 VanDerWaalsContact CB-CA 3.49Å; P205-S445 VanDerWaalsContact CB-N 3.32Å; T209-S445 WeakPolarHBondContact OG1-CA 3.31Å; T209-S445 PolarHBondContact OG1-O 3.24Å; T209-S445 VanDerWaalsContact OG1-O 3.08Å; T441-S445 WeakPolarHBondContact O-CB 3.07Å; T441-S445 PolarHBondContact O-N 3Å; T441-S445 PolarHBondContact O-OG 3.32Å; G442-S445 WeakPolarHBondContact O-CB 3.47Å; G442-S445 PolarHBondContact O-N 2.85Å; G442-S445 VanDerWaalsContact O-N 3.17Å; S445-F448 PolarHBondContact O-N 2.65Å; S445-L449 WeakPolarHBondContact O-CG 3.12Å; S445-L449 PolarHBondContact O-N 3.18Å
446	C	78.4	Confident	71.1	Confident	17 Å²	17	47.9 Å²	47.9	12%	0.115	26%	0.259	C	S	.	.	H	α-helix	trans	-67.7	-42.8	173.6	-63.5	0	0	0	0	113.8	G442 I443 L444 F448 L449 A450	G442-C446 PolarHBondContact O-N 3.2Å; G442-C446 PolarHBondContact O-SG 2.91Å; I443-C446 WeakPolarHBondContact O-CB 3.43Å; I443-C446 PolarHBondContact O-N 3.15Å; L444-C446 PolarHBondContact O-N 2.74Å; L444-C446 VanDerWaalsContact O-N 3.14Å; C446-F448 VanDerWaalsContact C-N 3.26Å; C446-F448 PolarHBondContact O-N 3.06Å; C446-L449 WeakPolarHBondContact O-CB 3.3Å; C446-L449 PolarHBondContact O-N 2.89Å; C446-A450 PolarHBondContact O-N 3.41Å
447	L	68.4	Low	69.7	Low	93 Å²	93	48.3 Å²	48.3	49%	0.487	26%	0.257	S	S	.	.	H	α-helix	trans	-62.5	-34.5	176	-72	175.8	0	0	0	112.1	I443 L444 L449 A450 L451	I443-L447 HydrophobicContact CG2-CD1 4.22Å; I443-L447 WeakPolarHBondContact O-CG 3.38Å; I443-L447 PolarHBondContact O-N 2.64Å; L444-L447 HydrophobicContact CD2-CD1 4.11Å; L444-L447 PolarHBondContact O-N 2.93Å; L447-L449 VanDerWaalsContact C-N 3.35Å; L447-A450 WeakPolarHBondContact O-CB 3.27Å; L447-A450 PolarHBondContact O-N 3.47Å; L447-L451 PolarHBondContact O-N 2.91Å
448	F	69.6	Low	68.2	Low	5 Å²	5	48.7 Å²	48.7	2%	0.022	26%	0.259	C	S	.	.	H	α-helix	trans	-67.9	-32.6	175.6	-83.5	-76.7	0	0	0	113.2	H180 A181 N202 P205 T209 L444 S445 C446 A450 L451 S452	H180-F448 HydrophobicContact CB-CD1 3.66Å; H180-F448 HydrophobicContact CB-CE1 3.32Å; H180-F448 HydrophobicContact CB-CZ 4.3Å; A181-F448 HydrophobicContact CB-CE1 4.07Å; A181-F448 HydrophobicContact CB-CZ 4.13Å; N202-F448 HydrophobicContact CB-CE2 4.25Å; N202-F448 HydrophobicContact CB-CZ 4.23Å; N202-F448 WeakPolarHBondContact OD1-CE2 3.21Å; N202-F448 WeakPolarHBondContact OD1-CZ 3.33Å; P205-F448 HydrophobicContact CB-CD2 3.38Å; P205-F448 HydrophobicContact CB-CE2 3.89Å; P205-F448 HydrophobicContact CB-CG 4.17Å; P205-F448 HydrophobicContact CG-CD2 2.97Å; P205-F448 HydrophobicContact CG-CE2 2.96Å; P205-F448 HydrophobicContact CG-CG 3.87Å; P205-F448 HydrophobicContact CG-CZ 3.82Å; T209-F448 HydrophobicContact CG2-CB 4.17Å; L444-F448 WeakPolarHBondContact O-CD2 3.15Å; L444-F448 PolarHBondContact O-N 3.36Å; S445-F448 PolarHBondContact O-N 2.65Å; C446-F448 VanDerWaalsContact C-N 3.26Å; C446-F448 PolarHBondContact O-N 3.06Å; F448-A450 PolarHBondContact O-N 2.96Å; F448-L451 PolarHBondContact O-N 3.44Å; F448-S452 WeakPolarHBondContact O-CB 3.11Å; F448-S452 PolarHBondContact O-N 3.45Å
449	L	69.8	Low	66.9	Low	9 Å²	9	50 Å²	50	5%	0.047	27%	0.266	C	S	.	.	H	α-helix	trans	-59.4	-35.2	171.1	-67.8	171.8	0	0	0	112.1	T209 L213 A238 C239 L242 S445 C446 L447	T209-L449 HydrophobicContact CG2-CD2 3.48Å; T209-L449 VanDerWaalsContact CG2-CD2 3.48Å; T209-L449 HydrophobicContact CG2-CG 3.86Å; L213-L449 HydrophobicContact CD1-CD2 3.72Å; L213-L449 HydrophobicContact CD2-CD2 3.4Å; L213-L449 VanDerWaalsContact CD2-CD2 3.4Å; L213-L449 HydrophobicContact CG-CD2 3.28Å; A238-L449 HydrophobicContact CB-CD1 3.69Å; A238-L449 HydrophobicContact CB-CD2 3.9Å; C239-L449 HydrophobicContact CB-CD1 4.2Å; C239-L449 WeakPolarHBondContact SG-CD1 3.32Å; L242-L449 HydrophobicContact CD1-CD1 3.63Å; L242-L449 HydrophobicContact CD1-CG 4.38Å; S445-L449 WeakPolarHBondContact O-CG 3.12Å; S445-L449 PolarHBondContact O-N 3.18Å; C446-L449 WeakPolarHBondContact O-CB 3.3Å; C446-L449 PolarHBondContact O-N 2.89Å; L447-L449 VanDerWaalsContact C-N 3.35Å
450	A	63.8	Low	65.7	Low	88 Å²	88	49.1 Å²	49.1	73%	0.727	26%	0.262	S	S	*	.	H	α-helix	trans	-75	-23.3	179.9	0	0	0	0	0	113.6	C446 L447 F448	C446-A450 PolarHBondContact O-N 3.41Å; L447-A450 WeakPolarHBondContact O-CB 3.27Å; L447-A450 PolarHBondContact O-N 3.47Å; F448-A450 PolarHBondContact O-N 2.96Å
451	L	58.7	Low	65.1	Low	115 Å²	115	48.9 Å²	48.9	60%	0.602	26%	0.259	S	S	*	.	H	α-helix	trans	-99.6	-25.5	-174.6	-73.7	157.6	0	0	0	113.6	L447 F448	L447-L451 PolarHBondContact O-N 2.91Å; F448-L451 PolarHBondContact O-N 3.44Å
452	S	55.6	Low	64.5	Low	35 Å²	35	50.5 Å²	50.5	25%	0.245	27%	0.268	C	S	.	.			trans	-90.6	124	-171.8	-174.6	0	0	0	0	112.2	F448	F448-S452 WeakPolarHBondContact O-CB 3.11Å; F448-S452 PolarHBondContact O-N 3.45Å
453	Q	56.1	Low	64.2	Low	165 Å²	165	50.6 Å²	50.6	77%	0.771	27%	0.267	S	S	*	.			trans	-110.5	-17.7	171.5	-76.7	-177	-35.2	0	0	114.1
454	D	52.8	Low	63.9	Low	70 Å²	70	46.4 Å²	46.4	37%	0.374	25%	0.246	S	C	.	.			trans	-134.2	115.6	-176.1	-166.2	-17.2	0	0	0	111	Y456 Q457	D454-Y456 PolarHBondContact OD1-N 3.05Å; D454-Q457 VanDerWaalsContact OD2-CD 3.3Å; D454-Q457 PolarHBondContact OD2-NE2 2.74Å
455	I	54	Low	64.1	Low	52 Å²	52	46.4 Å²	46.4	27%	0.267	25%	0.246	S	C	.	.	S	Bend	trans	-87.9	-28.9	-172.8	-59.7	173.2	0	0	0	112	I210 L213 L458 I459	I210-I455 HydrophobicContact CG1-CG2 4.23Å; I210-I455 HydrophobicContact CG2-CG2 4.15Å; L213-I455 HydrophobicContact CB-CD1 4.29Å; L213-I455 HydrophobicContact CD1-CD1 3.8Å; L213-I455 HydrophobicContact CD1-CG1 4.28Å; I455-L458 VanDerWaalsContact O-CB 3.31Å; I455-L458 WeakPolarHBondContact O-CB 3.32Å; I455-I459 HydrophobicContact CG2-CD1 4.48Å; I455-I459 WeakPolarHBondContact O-CG1 3.39Å; I455-I459 PolarHBondContact O-N 2.84Å
456	Y	52.9	Low	64.3	Low	133 Å²	133	47.7 Å²	47.7	52%	0.522	25%	0.253	S	S	.	.	H	α-helix	trans	-84.5	-45.1	-164.5	-75.9	-79	0	0	0	113.7	D454 L458 I459	D454-Y456 PolarHBondContact OD1-N 3.05Å; Y456-L458 PolarHBondContact O-N 3.14Å; Y456-I459 HydrophobicContact CD1-CD1 4.39Å; Y456-I459 PolarHBondContact O-N 2.97Å; Y456-I459 VanDerWaalsContact O-N 3.17Å
457	Q	55.7	Low	64.7	Low	49 Å²	49	47.4 Å²	47.4	23%	0.229	25%	0.249	C	C	.	.	H	α-helix	trans	-62	-27.7	174.9	-67.6	163.8	19	0	0	112.1	Y183 D454 N460 C461	Y183-Q457 HydrophobicContact CE1-CB 4.47Å; D454-Q457 VanDerWaalsContact OD2-CD 3.3Å; D454-Q457 PolarHBondContact OD2-NE2 2.74Å; Q457-N460 PolarHBondContact O-N 3.28Å; Q457-C461 PolarHBondContact O-N 2.85Å
458	L	52.4	Low	65.6	Low	9 Å²	9	44.6 Å²	44.6	5%	0.047	24%	0.235	C	C	.	.	H	α-helix	trans	-66.5	-37.9	179.3	-163	54.5	0	0	0	112	H180 Y183 I455 Y456 N460 C461 I462	H180-L458 VanDerWaalsContact CD2-CD1 3.4Å; H180-L458 WeakPolarHBondContact CD2-CD1 3.38Å; H180-L458 VanDerWaalsContact CE1-CD1 3.49Å; H180-L458 WeakPolarHBondContact CE1-CD1 3.11Å; H180-L458 WeakPolarHBondContact CE1-CD2 3.39Å; H180-L458 WeakPolarHBondContact CE1-CG 3.18Å; H180-L458 VanDerWaalsContact ND1-CD2 3.28Å; H180-L458 WeakPolarHBondContact ND1-CD2 3.37Å; H180-L458 VanDerWaalsContact NE2-CD1 3.33Å; H180-L458 WeakPolarHBondContact NE2-CD1 3.42Å; H180-L458 WeakPolarHBondContact NE2-CG 3.45Å; Y183-L458 HydrophobicContact CD1-CD1 3.85Å; Y183-L458 HydrophobicContact CG-CD1 4.12Å; I455-L458 VanDerWaalsContact O-CB 3.31Å; I455-L458 WeakPolarHBondContact O-CB 3.32Å; Y456-L458 PolarHBondContact O-N 3.14Å; L458-N460 VanDerWaalsContact C-N 3.35Å; L458-N460 PolarHBondContact O-N 3.15Å; L458-C461 PolarHBondContact O-N 3.21Å; L458-I462 HydrophobicContact CG-CD1 4.33Å; L458-I462 WeakPolarHBondContact O-CD1 3.41Å; L458-I462 WeakPolarHBondContact O-CG1 3.4Å; L458-I462 PolarHBondContact O-N 2.93Å; L458-I462 VanDerWaalsContact O-N 3.1Å
459	I	57.6	Low	66.4	Low	28 Å²	28	44.7 Å²	44.7	14%	0.144	24%	0.236	C	C	.	.	H	α-helix	trans	-60.2	-45.3	176.9	-66.7	165.7	0	0	0	110.3	F313 I455 Y456 C461 I462 Q463	F313-I459 HydrophobicContact CD2-CG2 4Å; F313-I459 HydrophobicContact CE2-CG2 4.23Å; F313-I459 HydrophobicContact CZ-CD1 4.41Å; I455-I459 HydrophobicContact CG2-CD1 4.48Å; I455-I459 WeakPolarHBondContact O-CG1 3.39Å; I455-I459 PolarHBondContact O-N 2.84Å; Y456-I459 HydrophobicContact CD1-CD1 4.39Å; Y456-I459 PolarHBondContact O-N 2.97Å; Y456-I459 VanDerWaalsContact O-N 3.17Å; I459-C461 PolarHBondContact O-N 3.2Å; I459-I462 PolarHBondContact O-N 2.89Å; I459-Q463 HydrophobicContact CG2-CG 4.02Å; I459-Q463 WeakPolarHBondContact O-CB 3.34Å; I459-Q463 WeakPolarHBondContact O-CG 3.35Å; I459-Q463 PolarHBondContact O-N 2.8Å
460	N	63.7	Low	67.4	Low	59 Å²	59	44.3 Å²	44.3	32%	0.316	23%	0.234	S	C	.	.	H	α-helix	trans	-62.7	-44.3	-178.4	-72.3	-17.9	0	0	0	112.2	Q457 L458 Q463 I464	Q457-N460 PolarHBondContact O-N 3.28Å; L458-N460 VanDerWaalsContact C-N 3.35Å; L458-N460 PolarHBondContact O-N 3.15Å; N460-Q463 PolarHBondContact O-N 2.81Å; N460-I464 PolarHBondContact O-N 2.85Å
461	C	64.8	Low	68.8	Low	2 Å²	2	40.5 Å²	40.5	1%	0.014	20%	0.203	C	C	.	.	H	α-helix	trans	-64.3	-43.7	178.9	-65.3	0	0	0	0	112.5	Y183 Q457 L458 I459 Q463 V465 D519	Y183-C461 HydrophobicContact CD2-CB 4.3Å; Y183-C461 HydrophobicContact CE2-CB 4.14Å; Y183-C461 WeakPolarHBondContact CE2-SG 3.4Å; Q457-C461 PolarHBondContact O-N 2.85Å; L458-C461 PolarHBondContact O-N 3.21Å; I459-C461 PolarHBondContact O-N 3.2Å; C461-Q463 VanDerWaalsContact C-N 3.34Å; C461-Q463 PolarHBondContact O-N 3.02Å; C461-V465 WeakPolarHBondContact O-CG2 3.29Å; C461-D519 VanDerWaalsContact SG-CB 3.59Å; C461-D519 PolarHBondContact SG-O 3.49Å; C461-D519 VanDerWaalsContact SG-O 3.34Å
462	I	69.2	Low	70.5	Confident	35 Å²	35	38.5 Å²	38.5	18%	0.179	19%	0.189	C	C	.	.	H	α-helix	trans	-61.8	-44.4	176.5	-61.3	160.4	0	0	0	111.2	L179 H180 I210 L458 I459 I464 V465 N466	L179-I462 HydrophobicContact CD2-CB 3.96Å; L179-I462 HydrophobicContact CD2-CG1 3.68Å; L179-I462 HydrophobicContact CD2-CG2 4.45Å; H180-I462 WeakPolarHBondContact NE2-CD1 3.22Å; H180-I462 VanDerWaalsContact NE2-CG1 3.26Å; H180-I462 WeakPolarHBondContact NE2-CG1 3.16Å; I210-I462 HydrophobicContact CD1-CD1 4.34Å; L458-I462 HydrophobicContact CG-CD1 4.33Å; L458-I462 WeakPolarHBondContact O-CD1 3.41Å; L458-I462 WeakPolarHBondContact O-CG1 3.4Å; L458-I462 PolarHBondContact O-N 2.93Å; L458-I462 VanDerWaalsContact O-N 3.1Å; I459-I462 PolarHBondContact O-N 2.89Å; I462-I464 PolarHBondContact O-N 2.85Å; I462-V465 PolarHBondContact O-N 3.01Å; I462-N466 WeakPolarHBondContact O-CB 3.41Å; I462-N466 PolarHBondContact O-N 3.33Å
463	Q	73.3	Confident	72.3	Confident	5 Å²	5	36.9 Å²	36.9	2%	0.023	18%	0.178	C	C	.	.	H	α-helix	trans	-68.4	-36.4	-168.8	-69.9	-79.7	60.4	0	0	112.1	Y309 N316 I459 N460 C461 V465 N466 W467	Y309-Q463 HydrophobicContact CD1-CB 4.23Å; Y309-Q463 HydrophobicContact CE1-CB 3.74Å; N316-Q463 PolarHBondContact ND2-OE1 3.41Å; I459-Q463 HydrophobicContact CG2-CG 4.02Å; I459-Q463 WeakPolarHBondContact O-CB 3.34Å; I459-Q463 WeakPolarHBondContact O-CG 3.35Å; I459-Q463 PolarHBondContact O-N 2.8Å; N460-Q463 PolarHBondContact O-N 2.81Å; C461-Q463 VanDerWaalsContact C-N 3.34Å; C461-Q463 PolarHBondContact O-N 3.02Å; Q463-V465 VanDerWaalsContact C-N 3.32Å; Q463-V465 PolarHBondContact O-N 3.34Å; Q463-N466 PolarHBondContact O-N 3.4Å; Q463-N466 PolarHBondContact OE1-ND2 2.97Å; Q463-W467 WeakPolarHBondContact O-CB 3.42Å; Q463-W467 PolarHBondContact O-N 3.32Å
464	I	76.1	Confident	74.1	Confident	5 Å²	5	29 Å²	29	3%	0.026	14%	0.141	C	C	.	.	H	α-helix	trans	-59.5	-46.9	174.2	-65.2	165.4	0	0	0	110.5	N460 I462 N466 W467 L468 V509 P512 T520	N460-I464 PolarHBondContact O-N 2.85Å; I462-I464 PolarHBondContact O-N 2.85Å; I464-N466 VanDerWaalsContact C-N 3.34Å; I464-W467 PolarHBondContact O-N 3.43Å; I464-L468 HydrophobicContact CG2-CD1 4.44Å; I464-L468 PolarHBondContact O-N 3.33Å; I464-V509 HydrophobicContact CG2-CG1 4.48Å; I464-P512 HydrophobicContact CD1-CB 3.67Å; I464-P512 HydrophobicContact CG1-CB 3.92Å; I464-P512 HydrophobicContact CG1-CG 4.27Å; I464-T520 HydrophobicContact CD1-CG2 4.09Å; I464-T520 WeakPolarHBondContact CD1-OG1 3.5Å; I464-T520 HydrophobicContact CG2-CG2 4.47Å
465	V	76.5	Confident	76.1	Confident	0 Å²	0	29 Å²	29	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-71.1	-34.4	-177.6	-167.9	0	0	0	0	111.3	I175 L179 C461 I462 Q463 L468 A469 M527	I175-V465 HydrophobicContact CB-CG1 3.98Å; I175-V465 HydrophobicContact CD1-CG1 3.36Å; I175-V465 HydrophobicContact CG1-CG1 3.48Å; I175-V465 VanDerWaalsContact CG1-CG1 3.48Å; I175-V465 HydrophobicContact CG2-CB 4.1Å; I175-V465 HydrophobicContact CG2-CG1 3.27Å; L179-V465 HydrophobicContact CD1-CB 4.29Å; L179-V465 HydrophobicContact CD1-CG1 4.3Å; L179-V465 HydrophobicContact CD1-CG2 3.88Å; L179-V465 HydrophobicContact CD2-CG2 4.39Å; C461-V465 WeakPolarHBondContact O-CG2 3.29Å; I462-V465 PolarHBondContact O-N 3.01Å; Q463-V465 VanDerWaalsContact C-N 3.32Å; Q463-V465 PolarHBondContact O-N 3.34Å; V465-L468 PolarHBondContact O-N 2.71Å; V465-A469 WeakPolarHBondContact O-CB 3.26Å; V465-A469 PolarHBondContact O-N 3.43Å; V465-M527 HydrophobicContact CG1-CB 4.26Å; V465-M527 HydrophobicContact CG1-CG 4.49Å; V465-M527 HydrophobicContact CG1-SD 4.15Å
466	N	81.2	Confident	78	Confident	28 Å²	28	26.5 Å²	26.5	15%	0.15	13%	0.127	C	C	.	.	H	α-helix	trans	-64.7	-43.6	172.1	-171.5	35.3	0	0	0	111.8	N316 I462 Q463 I464 A469 V470	N316-N466 PolarHBondContact ND2-ND2 3.12Å; I462-N466 WeakPolarHBondContact O-CB 3.41Å; I462-N466 PolarHBondContact O-N 3.33Å; Q463-N466 PolarHBondContact O-N 3.4Å; Q463-N466 PolarHBondContact OE1-ND2 2.97Å; I464-N466 VanDerWaalsContact C-N 3.34Å; N466-A469 WeakPolarHBondContact O-CB 3.46Å; N466-A469 PolarHBondContact O-N 3.34Å; N466-V470 WeakPolarHBondContact O-CG2 3.3Å; N466-V470 PolarHBondContact O-N 3.23Å
467	W	86.4	Confident	80	Confident	10 Å²	10	20.2 Å²	20.2	4%	0.038	10%	0.102	C	C	.	.	H	α-helix	trans	-67.5	-35.5	176.4	-75.3	121.2	0	0	0	112.9	F135 Y309 L312 Q463 I464 V470 A471 F501 L508 V509	F135-W467 HydrophobicContact CD1-CH2 4.2Å; F135-W467 AromaticContact CE1-CH2 3.69Å; F135-W467 HydrophobicContact CE1-CH2 3.69Å; F135-W467 AromaticContact CE1-CZ3 3.7Å; F135-W467 HydrophobicContact CE1-CZ3 3.7Å; Y309-W467 AromaticContact CE1-CD1 3.94Å; Y309-W467 AromaticContact CZ-CD1 3.94Å; L312-W467 HydrophobicContact CB-CZ2 4.07Å; L312-W467 HydrophobicContact CD1-CH2 4.44Å; L312-W467 HydrophobicContact CD1-CZ2 3.97Å; L312-W467 HydrophobicContact CG-CZ2 4.47Å; Q463-W467 WeakPolarHBondContact O-CB 3.42Å; Q463-W467 PolarHBondContact O-N 3.32Å; I464-W467 PolarHBondContact O-N 3.43Å; W467-V470 HydrophobicContact CE3-CB 4.2Å; W467-V470 HydrophobicContact CE3-CG1 4.16Å; W467-V470 HydrophobicContact CZ3-CG1 4.15Å; W467-V470 PolarHBondContact O-N 3.1Å; W467-A471 WeakPolarHBondContact O-CB 3.31Å; W467-A471 PolarHBondContact O-N 3.39Å; W467-F501 HydrophobicContact CZ3-CE2 4.43Å; W467-F501 HydrophobicContact CZ3-CZ 4.12Å; W467-L508 HydrophobicContact CD2-CD1 3.92Å; W467-L508 HydrophobicContact CE3-CD1 4.18Å; W467-L508 HydrophobicContact CG-CB 4.25Å; W467-L508 HydrophobicContact CG-CD1 4.47Å; W467-L508 HydrophobicContact CH2-CD1 4.18Å; W467-L508 HydrophobicContact CZ2-CD1 3.89Å; W467-L508 HydrophobicContact CZ3-CD1 4.3Å; W467-V509 HydrophobicContact CB-CG2 3.82Å
468	L	87	Confident	81.9	Confident	35 Å²	35	20.4 Å²	20.4	18%	0.183	10%	0.102	C	C	.	.	H	α-helix	trans	-58.7	-48.3	168.6	-82.3	171.5	0	0	0	111.1	I464 V465 V470 A471 F472 V509 L524 M527	I464-L468 HydrophobicContact CG2-CD1 4.44Å; I464-L468 PolarHBondContact O-N 3.33Å; V465-L468 PolarHBondContact O-N 2.71Å; L468-V470 PolarHBondContact O-N 3.34Å; L468-A471 WeakPolarHBondContact O-CB 3.2Å; L468-A471 PolarHBondContact O-N 3Å; L468-F472 WeakPolarHBondContact O-CD2 3.47Å; L468-F472 PolarHBondContact O-N 3.48Å; L468-V509 HydrophobicContact CB-CG2 4.49Å; L468-V509 HydrophobicContact CD1-CG1 4.45Å; L468-V509 HydrophobicContact CD2-CB 4.44Å; L468-V509 HydrophobicContact CD2-CG1 3.72Å; L468-V509 HydrophobicContact CD2-CG2 3.96Å; L468-V509 HydrophobicContact CG-CG1 3.9Å; L468-V509 HydrophobicContact CG-CG2 3.76Å; L468-L524 HydrophobicContact CD1-CD2 3.69Å; L468-M527 HydrophobicContact CD1-CE 4.25Å; L468-M527 HydrophobicContact CD1-SD 4.38Å
469	A	86.7	Confident	83.8	Confident	6 Å²	6	22.6 Å²	22.6	5%	0.05	11%	0.114	C	C	.	.	H	α-helix	trans	-58.3	-45.8	176.1	0	0	0	0	0	112.7	V465 N466 A471 F472 A473	V465-A469 WeakPolarHBondContact O-CB 3.26Å; V465-A469 PolarHBondContact O-N 3.43Å; N466-A469 WeakPolarHBondContact O-CB 3.46Å; N466-A469 PolarHBondContact O-N 3.34Å; A469-A471 VanDerWaalsContact C-N 3.31Å; A469-A471 PolarHBondContact O-N 3.17Å; A469-F472 PolarHBondContact O-N 3.05Å; A469-A473 WeakPolarHBondContact O-CB 3.36Å; A469-A473 PolarHBondContact O-N 3.3Å
470	V	90.9	Very high	85.5	Confident	2 Å²	2	21.4 Å²	21.4	1%	0.012	11%	0.108	C	C	.	.	H	α-helix	trans	-63.5	-36.3	176.1	171.7	0	0	0	0	111.5	W318 N466 W467 L468 A473 T474 F501	W318-V470 HydrophobicContact CH2-CG1 4.15Å; W318-V470 HydrophobicContact CZ2-CG1 4.04Å; W318-V470 HydrophobicContact CZ2-CG2 4.35Å; N466-V470 WeakPolarHBondContact O-CG2 3.3Å; N466-V470 PolarHBondContact O-N 3.23Å; W467-V470 HydrophobicContact CE3-CB 4.2Å; W467-V470 HydrophobicContact CE3-CG1 4.16Å; W467-V470 HydrophobicContact CZ3-CG1 4.15Å; W467-V470 PolarHBondContact O-N 3.1Å; L468-V470 PolarHBondContact O-N 3.34Å; V470-A473 PolarHBondContact O-N 3.35Å; V470-T474 WeakPolarHBondContact O-CB 3.35Å; V470-T474 PolarHBondContact O-N 3.08Å; V470-T474 PolarHBondContact O-OG1 2.74Å; V470-F501 HydrophobicContact CG1-CE1 3.49Å; V470-F501 VanDerWaalsContact CG1-CE1 3.49Å; V470-F501 HydrophobicContact CG1-CZ 3.63Å
471	A	93.5	Very high	86.8	Confident	8 Å²	8	20.5 Å²	20.5	7%	0.066	10%	0.1	C	C	.	.	H	α-helix	trans	-62.8	-47.2	174	0	0	0	0	0	111.2	W467 L468 A469 A473 T474 M475 L502 C505	W467-A471 WeakPolarHBondContact O-CB 3.31Å; W467-A471 PolarHBondContact O-N 3.39Å; L468-A471 WeakPolarHBondContact O-CB 3.2Å; L468-A471 PolarHBondContact O-N 3Å; A469-A471 VanDerWaalsContact C-N 3.31Å; A469-A471 PolarHBondContact O-N 3.17Å; A471-A473 PolarHBondContact O-N 2.98Å; A471-T474 PolarHBondContact O-N 3.01Å; A471-M475 WeakPolarHBondContact O-CB 3.15Å; A471-M475 VanDerWaalsContact O-CG 3.3Å; A471-M475 WeakPolarHBondContact O-CG 3.33Å; A471-M475 PolarHBondContact O-N 2.95Å; A471-L502 HydrophobicContact CB-CD1 3.83Å; A471-L502 WeakPolarHBondContact O-CD1 3.48Å; A471-C505 HydrophobicContact CB-CB 3.96Å
472	F	93.5	Very high	88	Confident	73 Å²	73	30.2 Å²	30.2	32%	0.32	14%	0.136	S	C	.	.	H	α-helix	trans	-64.1	-39.4	175.4	-85.8	-83.7	0	0	0	112.4	I160 F164 I168 L468 A469 M475 S476	I160-F472 HydrophobicContact CD1-CB 3.94Å; I160-F472 HydrophobicContact CG1-CB 4.16Å; F164-F472 HydrophobicContact CD2-CD1 4.46Å; F164-F472 HydrophobicContact CE1-CD1 4.25Å; F164-F472 HydrophobicContact CE1-CE1 4.43Å; F164-F472 HydrophobicContact CE2-CD1 4.05Å; F164-F472 WeakPolarHBondContact CE2-O 3.35Å; F164-F472 AromaticContact CZ-CD1 3.94Å; F164-F472 HydrophobicContact CZ-CD1 3.94Å; I168-F472 HydrophobicContact CD1-CE1 4.3Å; I168-F472 HydrophobicContact CG2-CD1 4.17Å; I168-F472 HydrophobicContact CG2-CE1 4.43Å; L468-F472 WeakPolarHBondContact O-CD2 3.47Å; L468-F472 PolarHBondContact O-N 3.48Å; A469-F472 PolarHBondContact O-N 3.05Å; F472-M475 PolarHBondContact O-N 3.34Å; F472-S476 PolarHBondContact O-N 2.64Å; F472-S476 PolarHBondContact O-OG 3.32Å
473	A	93.5	Very high	89.1	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-61.9	-43.8	174.2	0	0	0	0	0	111.4	Y143 L146 D156 I160 A469 V470 A471 S476	Y143-A473 HydrophobicContact CE2-CB 4.04Å; Y143-A473 WeakPolarHBondContact OH-CB 3.35Å; L146-A473 WeakPolarHBondContact CD1-O 3.49Å; D156-A473 HydrophobicContact CB-CB 4.32Å; I160-A473 HydrophobicContact CD1-CB 4.29Å; I160-A473 HydrophobicContact CG1-CB 4.27Å; A469-A473 WeakPolarHBondContact O-CB 3.36Å; A469-A473 PolarHBondContact O-N 3.3Å; V470-A473 PolarHBondContact O-N 3.35Å; A471-A473 PolarHBondContact O-N 2.98Å; A473-S476 WeakPolarHBondContact O-CB 3.3Å; A473-S476 PolarHBondContact O-N 3.34Å; A473-S476 VanDerWaalsContact O-N 3.16Å
474	T	94.9	Very high	89.8	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-64.4	-42.4	174.4	-54	0	0	0	0	112	V470 A471 S476 L477 P498 F501 L502	V470-T474 WeakPolarHBondContact O-CB 3.35Å; V470-T474 PolarHBondContact O-N 3.08Å; V470-T474 PolarHBondContact O-OG1 2.74Å; A471-T474 PolarHBondContact O-N 3.01Å; T474-S476 PolarHBondContact O-N 2.87Å; T474-L477 WeakPolarHBondContact O-CB 3.4Å; T474-L477 PolarHBondContact O-N 3.02Å; T474-P498 HydrophobicContact CG2-CB 4.02Å; T474-F501 HydrophobicContact CG2-CD1 4.02Å; T474-F501 WeakPolarHBondContact OG1-CD1 3.41Å; T474-F501 WeakPolarHBondContact OG1-CE1 3.26Å; T474-L502 HydrophobicContact CG2-CB 4.15Å
475	M	95	Very high	90.3	Very high	69 Å²	69	40.1 Å²	40.1	34%	0.34	20%	0.2	S	C	.	.	H	α-helix	trans	-60.1	-30.8	173.6	-74.6	173.9	55.6	0	0	112.4	F164 A471 F472 L477 F478 L479 L502	F164-M475 HydrophobicContact CE1-CE 4.35Å; F164-M475 HydrophobicContact CE2-CB 4.34Å; F164-M475 HydrophobicContact CZ-CB 3.91Å; F164-M475 HydrophobicContact CZ-CE 3.99Å; A471-M475 WeakPolarHBondContact O-CB 3.15Å; A471-M475 VanDerWaalsContact O-CG 3.3Å; A471-M475 WeakPolarHBondContact O-CG 3.33Å; A471-M475 PolarHBondContact O-N 2.95Å; F472-M475 PolarHBondContact O-N 3.34Å; M475-L477 PolarHBondContact O-N 3.46Å; M475-F478 PolarHBondContact O-N 3.39Å; M475-F478 VanDerWaalsContact O-N 3.12Å; M475-L479 PolarHBondContact O-N 3.41Å; M475-L479 VanDerWaalsContact O-N 3.12Å; M475-L502 HydrophobicContact CG-CD1 3.75Å; M475-L502 HydrophobicContact CG-CD2 3.67Å; M475-L502 HydrophobicContact CG-CG 4.39Å; M475-L502 HydrophobicContact SD-CD1 4.37Å
476	S	94.1	Very high	90.6	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-61.2	-32.3	177	-57.1	0	0	0	0	111	A163 F164 F472 A473 T474 F478 L479 L480	A163-S476 VanDerWaalsContact CB-CB 3.44Å; F164-S476 VanDerWaalsContact CE2-OG 3.29Å; F164-S476 WeakPolarHBondContact CE2-OG 3.21Å; F472-S476 PolarHBondContact O-N 2.64Å; F472-S476 PolarHBondContact O-OG 3.32Å; A473-S476 WeakPolarHBondContact O-CB 3.3Å; A473-S476 PolarHBondContact O-N 3.34Å; A473-S476 VanDerWaalsContact O-N 3.16Å; T474-S476 PolarHBondContact O-N 2.87Å; S476-F478 PolarHBondContact O-N 3.45Å; S476-L479 PolarHBondContact O-N 3.35Å; S476-L480 VanDerWaalsContact O-CB 3.26Å; S476-L480 WeakPolarHBondContact O-CB 3.49Å; S476-L480 WeakPolarHBondContact O-CD1 3.37Å; S476-L480 WeakPolarHBondContact O-CG 3.29Å; S476-L480 PolarHBondContact O-N 2.82Å
477	L	94	Very high	90.8	Very high	1 Å²	1	48.1 Å²	48.1	1%	0.005	25%	0.247	C	C	.	.	H	α-helix	trans	-59.7	-47.7	174.2	-169.5	157	0	0	0	111.1	C142 E145 L146 T474 M475 L480 R481 L495 P498	C142-L477 HydrophobicContact CB-CD1 4.12Å; E145-L477 HydrophobicContact CB-CD1 4.39Å; L146-L477 HydrophobicContact CD1-CB 4.34Å; L146-L477 HydrophobicContact CD2-CB 4.01Å; L146-L477 HydrophobicContact CG-CB 4.23Å; L146-L477 HydrophobicContact CG-CD1 4.4Å; T474-L477 WeakPolarHBondContact O-CB 3.4Å; T474-L477 PolarHBondContact O-N 3.02Å; M475-L477 PolarHBondContact O-N 3.46Å; L477-L480 PolarHBondContact O-N 2.89Å; L477-R481 HydrophobicContact CD2-CG 3.95Å; L477-R481 WeakPolarHBondContact O-CB 3.41Å; L477-R481 WeakPolarHBondContact O-CG 3.37Å; L477-R481 PolarHBondContact O-N 3.43Å; L477-L495 HydrophobicContact CD2-CD2 3.67Å; L477-P498 HydrophobicContact CD1-CG 4.05Å; L477-P498 HydrophobicContact CD2-CG 4.11Å
478	F	95	Very high	90.7	Very high	53 Å²	53	55.1 Å²	55.1	23%	0.232	28%	0.28	C	S	.	.	H	α-helix	trans	-64.1	-40.7	178.3	-68.1	-88	0	0	0	112.6	M475 S476 R481 R482 L495 P498 A499 L502	M475-F478 PolarHBondContact O-N 3.39Å; M475-F478 VanDerWaalsContact O-N 3.12Å; S476-F478 PolarHBondContact O-N 3.45Å; F478-R481 WeakPolarHBondContact O-CB 3.45Å; F478-R482 PolarHBondContact O-N 3.42Å; F478-L495 HydrophobicContact CD1-CD2 4.02Å; F478-L495 HydrophobicContact CE1-CB 4.2Å; F478-L495 HydrophobicContact CE1-CD2 3.95Å; F478-L495 HydrophobicContact CE1-CG 4.48Å; F478-P498 HydrophobicContact CE2-CB 3.63Å; F478-P498 HydrophobicContact CZ-CB 3.71Å; F478-A499 HydrophobicContact CZ-CB 4.04Å; F478-L502 HydrophobicContact CE2-CD2 4.37Å
479	L	93.7	Very high	90.8	Very high	56 Å²	56	55.4 Å²	55.4	29%	0.293	28%	0.279	S	S	.	.	H	α-helix	trans	-67.4	-45.7	177	-67.2	-176.8	0	0	0	111.3	A163 F164 M475 S476 R481 R482 S483	A163-L479 HydrophobicContact CB-CB 4.4Å; F164-L479 HydrophobicContact CD1-CD1 3.85Å; F164-L479 HydrophobicContact CD2-CD1 4.38Å; F164-L479 HydrophobicContact CE1-CD1 3.32Å; F164-L479 HydrophobicContact CE2-CD1 3.9Å; F164-L479 HydrophobicContact CG-CD1 4.35Å; F164-L479 HydrophobicContact CZ-CD1 3.34Å; F164-L479 HydrophobicContact CZ-CG 4.39Å; M475-L479 PolarHBondContact O-N 3.41Å; M475-L479 VanDerWaalsContact O-N 3.12Å; S476-L479 PolarHBondContact O-N 3.35Å; L479-R481 VanDerWaalsContact C-N 3.29Å; L479-R481 PolarHBondContact O-N 3.17Å; L479-R482 CarbonylContact O-C 3.31Å; L479-R482 WeakPolarHBondContact O-CA 2.89Å; L479-R482 PolarHBondContact O-N 3.32Å; L479-S483 PolarHBondContact O-N 3.04Å; L479-S483 PolarHBondContact O-OG 3.12Å
480	L	93.1	Very high	90.8	Very high	2 Å²	2	58.5 Å²	58.5	1%	0.01	30%	0.297	C	S	.	.	H	α-helix	trans	-67.7	-28	179	-66.6	169.1	0	0	0	112.3	L146 L149 I150 T162 A163 S476 L477 R482 M484 R489	L146-L480 HydrophobicContact CD2-CD1 3.87Å; L149-L480 HydrophobicContact CD2-CB 4.34Å; L149-L480 HydrophobicContact CD2-CD1 4.39Å; I150-L480 HydrophobicContact CD1-CD1 3.59Å; T162-L480 HydrophobicContact CG2-CD2 4.12Å; A163-L480 HydrophobicContact CB-CD1 4.34Å; A163-L480 HydrophobicContact CB-CD2 4.28Å; A163-L480 HydrophobicContact CB-CG 4.03Å; S476-L480 VanDerWaalsContact O-CB 3.26Å; S476-L480 WeakPolarHBondContact O-CB 3.49Å; S476-L480 WeakPolarHBondContact O-CD1 3.37Å; S476-L480 WeakPolarHBondContact O-CG 3.29Å; S476-L480 PolarHBondContact O-N 2.82Å; L477-L480 PolarHBondContact O-N 2.89Å; L480-R482 VanDerWaalsContact C-N 3.26Å; L480-R482 PolarHBondContact O-N 3.39Å; L480-M484 HydrophobicContact CD2-CE 4.26Å; L480-M484 HydrophobicContact CD2-SD 4.19Å; L480-M484 CarbonylContact O-C 3.56Å; L480-M484 WeakPolarHBondContact O-CA 3.47Å; L480-M484 PolarHBondContact O-N 3.3Å; L480-R489 PolarHBondContact O-NH2 3.32Å
481	R	91.1	Very high	90.6	Very high	40 Å²	40	60.1 Å²	60.1	15%	0.151	31%	0.305	C	S	.	.	H	α-helix	trans	-56.4	-39.8	166.4	-71.4	-101.5	169.7	148.4	-8.4	112.3	E145 L477 F478 L479 R489 V493 L495	E145-R481 IonicContact OE1-CZ 3.29Å; E145-R481 IonicContact OE1-NE 3.71Å; E145-R481 PolarHBondContact OE1-NE 3.29Å; E145-R481 IonicContact OE1-NH2 2.74Å; E145-R481 PolarHBondContact OE1-NH2 3.06Å; E145-R481 IonicContact OE2-CZ 3.25Å; E145-R481 IonicContact OE2-NE 2.71Å; E145-R481 IonicContact OE2-NH2 3.64Å; E145-R481 PolarHBondContact OE2-NH2 2.76Å; L477-R481 HydrophobicContact CD2-CG 3.95Å; L477-R481 WeakPolarHBondContact O-CB 3.41Å; L477-R481 WeakPolarHBondContact O-CG 3.37Å; L477-R481 PolarHBondContact O-N 3.43Å; F478-R481 WeakPolarHBondContact O-CB 3.45Å; L479-R481 VanDerWaalsContact C-N 3.29Å; L479-R481 PolarHBondContact O-N 3.17Å; R481-R489 VanDerWaalsContact CA-NH2 3.33Å; R481-R489 VanDerWaalsContact CD-NH1 3.29Å; R481-R489 VanDerWaalsContact CG-NH1 3.31Å; R481-V493 VanDerWaalsContact CZ-O 3.24Å; R481-V493 PolarHBondContact NH1-O 2.91Å; R481-V493 VanDerWaalsContact NH1-O 3.14Å; R481-V493 VanDerWaalsContact NH2-N 3.16Å; R481-V493 PolarHBondContact NH2-O 3.38Å; R481-L495 HydrophobicContact CG-CD2 4.02Å
482	R	90.3	Very high	90.4	Very high	207 Å²	207	67 Å²	67	78%	0.781	33%	0.334	S	S	*	.	H	α-helix	trans	-85.1	-41.8	-178.6	-66.9	-180	177.8	169.8	-0.1	112.6	F478 L479 L480	F478-R482 PolarHBondContact O-N 3.42Å; L479-R482 CarbonylContact O-C 3.31Å; L479-R482 WeakPolarHBondContact O-CA 2.89Å; L479-R482 PolarHBondContact O-N 3.32Å; L480-R482 VanDerWaalsContact C-N 3.26Å; L480-R482 PolarHBondContact O-N 3.39Å
483	S	90.6	Very high	90.3	Very high	88 Å²	88	63.5 Å²	63.5	62%	0.615	32%	0.318	S	S	*	.	H	α-helix	trans	-79.1	-30.1	-176	-58.3	0	0	0	0	113.5	L479 P485	L479-S483 PolarHBondContact O-N 3.04Å; L479-S483 PolarHBondContact O-OG 3.12Å; S483-P485 VanDerWaalsContact C-CD 3.46Å
484	M	89.8	Confident	90.3	Very high	79 Å²	79	67.8 Å²	67.8	39%	0.389	34%	0.341	S	S	.	.			trans	-127.5	66	-179.8	-60.5	-177.1	-175.8	0	0	111.1	T162 L480 N486 A487 R489	T162-M484 HydrophobicContact CG2-CE 4.23Å; L480-M484 HydrophobicContact CD2-CE 4.26Å; L480-M484 HydrophobicContact CD2-SD 4.19Å; L480-M484 CarbonylContact O-C 3.56Å; L480-M484 WeakPolarHBondContact O-CA 3.47Å; L480-M484 PolarHBondContact O-N 3.3Å; M484-N486 VanDerWaalsContact C-N 3.35Å; M484-N486 PolarHBondContact O-N 2.94Å; M484-A487 HydrophobicContact CB-CB 4.06Å; M484-R489 PolarHBondContact O-NH2 3Å
485	P	84.7	Confident	90.2	Very high	86 Å²	86	70.8 Å²	70.8	56%	0.558	36%	0.357	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.4	-33.6	-177.3	27.5	-33.9	0	0	0	112.5	S483	S483-P485 VanDerWaalsContact C-CD 3.46Å
486	N	84	Confident	90.2	Very high	162 Å²	162	72.2 Å²	72.2	87%	0.866	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.6	-0.3	-176	-60.7	-20	0	0	0	113.8	M484 Q488	M484-N486 VanDerWaalsContact C-N 3.35Å; M484-N486 PolarHBondContact O-N 2.94Å; N486-Q488 PolarHBondContact O-N 3.47Å
487	A	85	Confident	90.3	Very high	34 Å²	34	75.8 Å²	75.8	28%	0.281	38%	0.38	S	S	.	.	S	Bend	trans	-68.8	132.6	179	0	0	0	0	0	110.5	L149 M484 R489	L149-A487 HydrophobicContact CD1-CB 3.7Å; M484-A487 HydrophobicContact CB-CB 4.06Å; A487-R489 PolarHBondContact O-N 3.31Å; A487-R489 VanDerWaalsContact O-N 3.12Å
488	Q	84.6	Confident	90.3	Very high	157 Å²	157	75.7 Å²	75.7	73%	0.734	38%	0.38	S	S	*	.			trans	-63.8	114.1	177	-170.5	-173.1	20.2	0	0	110	N486	N486-Q488 PolarHBondContact O-N 3.47Å
489	R	87.9	Confident	90.4	Very high	41 Å²	41	74.9 Å²	74.9	16%	0.155	38%	0.383	C	S	.	.			trans	-108.4	115.3	176.7	-66.1	174.6	-158.6	-141.4	-4.3	109	E145 L149 L480 R481 M484 A487 I491	E145-R489 WeakPolarHBondContact OE1-CD 3.49Å; E145-R489 IonicContact OE1-CZ 3.09Å; E145-R489 IonicContact OE1-NH1 3.75Å; E145-R489 PolarHBondContact OE1-NH1 3.03Å; L149-R489 HydrophobicContact CD1-CG 4.47Å; L480-R489 PolarHBondContact O-NH2 3.32Å; R481-R489 VanDerWaalsContact CA-NH2 3.33Å; R481-R489 VanDerWaalsContact CD-NH1 3.29Å; R481-R489 VanDerWaalsContact CG-NH1 3.31Å; M484-R489 PolarHBondContact O-NH2 3Å; A487-R489 PolarHBondContact O-N 3.31Å; A487-R489 VanDerWaalsContact O-N 3.12Å; R489-I491 VanDerWaalsContact C-N 3.26Å
490	V	87	Confident	90.4	Very high	70 Å²	70	76.4 Å²	76.4	42%	0.424	39%	0.391	S	S	.	.	S	Bend	trans	-65.9	-37.9	174.7	-177	0	0	0	0	110.1	K332	K332-V490 HydrophobicContact CB-CG1 4.4Å; K332-V490 HydrophobicContact CB-CG2 3.98Å; K332-V490 HydrophobicContact CD-CG2 3.68Å; K332-V490 HydrophobicContact CG-CG2 3.73Å
491	I	88.2	Confident	90.6	Very high	36 Å²	36	76.3 Å²	76.3	19%	0.185	39%	0.39	C	S	.	.			trans	-121.5	128.9	174.5	-61	-169.2	0	0	0	108.8	Y141 E145 P336 R489 V493	Y141-I491 HydrophobicContact CE2-CG2 4.16Å; E145-I491 WeakPolarHBondContact CG-O 3.37Å; P336-I491 HydrophobicContact CB-CD1 3.22Å; P336-I491 HydrophobicContact CG-CD1 3.16Å; P336-I491 HydrophobicContact CG-CG1 4.21Å; R489-I491 VanDerWaalsContact C-N 3.26Å; I491-V493 HydrophobicContact CG2-CG2 4.13Å
492	K	89.5	Confident	90.8	Very high	153 Å²	153	76 Å²	76	67%	0.665	39%	0.392	S	S	*	.			trans	-120.4	95.8	174.8	-169.4	179.4	-178.9	-179.6	0	108.2
493	V	91.2	Very high	91	Very high	0 Å²	0	71.9 Å²	71.9	0%	0	38%	0.383	C	S	.	.			trans	-63.6	138.3	178.9	172	0	0	0	0	110.2	Y141 E145 R481 I491 L495 F497 P498	Y141-V493 HydrophobicContact CD1-CB 4.36Å; Y141-V493 HydrophobicContact CD1-CG1 3.64Å; Y141-V493 HydrophobicContact CD1-CG2 3.95Å; Y141-V493 HydrophobicContact CD2-CG2 4.04Å; Y141-V493 HydrophobicContact CE1-CB 3.94Å; Y141-V493 HydrophobicContact CE1-CG1 3.43Å; Y141-V493 VanDerWaalsContact CE1-CG1 3.43Å; Y141-V493 HydrophobicContact CE1-CG2 3.76Å; Y141-V493 HydrophobicContact CE2-CG2 3.84Å; Y141-V493 HydrophobicContact CG-CG2 4.08Å; Y141-V493 WeakPolarHBondContact O-CG2 3.16Å; E145-V493 HydrophobicContact CB-CG2 3.89Å; E145-V493 VanDerWaalsContact OE2-CB 3.3Å; E145-V493 WeakPolarHBondContact OE2-CB 3.42Å; E145-V493 PolarHBondContact OE2-N 3.22Å; R481-V493 VanDerWaalsContact CZ-O 3.24Å; R481-V493 PolarHBondContact NH1-O 2.91Å; R481-V493 VanDerWaalsContact NH1-O 3.14Å; R481-V493 VanDerWaalsContact NH2-N 3.16Å; R481-V493 PolarHBondContact NH2-O 3.38Å; I491-V493 HydrophobicContact CG2-CG2 4.13Å; V493-L495 PolarHBondContact O-N 3.37Å; V493-F497 HydrophobicContact CG1-CB 4.31Å; V493-P498 HydrophobicContact CG1-CG 3.69Å
494	N	93.3	Very high	91	Very high	89 Å²	89	68.4 Å²	68.4	48%	0.476	36%	0.362	S	S	.	.			trans	-65.7	130	172.2	-170.7	-5.5	0	0	0	109.7	I496 F497 P498	N494-I496 PolarHBondContact O-N 3.47Å; N494-F497 HydrophobicContact CB-CD2 3.94Å; N494-F497 HydrophobicContact CB-CE2 4.09Å; N494-F497 PolarHBondContact O-N 3.12Å; N494-P498 WeakPolarHBondContact O-CD 3.28Å
495	L	92.4	Very high	91.1	Very high	64 Å²	64	64.7 Å²	64.7	34%	0.335	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-16.2	-173.5	-70.4	-179.3	0	0	0	114.3	L477 F478 R481 V493 F497 P498 A499	L477-L495 HydrophobicContact CD2-CD2 3.67Å; F478-L495 HydrophobicContact CD1-CD2 4.02Å; F478-L495 HydrophobicContact CE1-CB 4.2Å; F478-L495 HydrophobicContact CE1-CD2 3.95Å; F478-L495 HydrophobicContact CE1-CG 4.48Å; R481-L495 HydrophobicContact CG-CD2 4.02Å; V493-L495 PolarHBondContact O-N 3.37Å; L495-F497 VanDerWaalsContact C-N 3.33Å; L495-P498 WeakPolarHBondContact O-CD 3.12Å; L495-A499 WeakPolarHBondContact O-CB 3.43Å; L495-A499 PolarHBondContact O-N 3.44Å; L495-A499 VanDerWaalsContact O-N 3.11Å
496	I	95.4	Very high	91.3	Very high	98 Å²	98	63.8 Å²	63.8	50%	0.503	34%	0.337	S	S	.	.	H	α-helix	trans	-59.6	-44.3	171.9	-60.2	175.8	0	0	0	110.6	N494 A499 I500	N494-I496 PolarHBondContact O-N 3.47Å; I496-A499 WeakPolarHBondContact O-CB 3.23Å; I496-A499 PolarHBondContact O-N 3.28Å; I496-I500 HydrophobicContact CG2-CD1 3.77Å; I496-I500 HydrophobicContact CG2-CG1 4.41Å; I496-I500 WeakPolarHBondContact O-CG1 3.38Å; I496-I500 PolarHBondContact O-N 3.3Å
497	F	94.5	Very high	91.5	Very high	75 Å²	75	60.3 Å²	60.3	33%	0.329	31%	0.314	S	S	.	.	H	α-helix	trans	-67.4	-47.7	-177.1	-61.2	-68.3	0	0	0	113.3	L138 Y141 V493 N494 L495 A499 I500 F501	L138-F497 HydrophobicContact CD2-CB 4.13Å; L138-F497 HydrophobicContact CD2-CD1 3.58Å; L138-F497 HydrophobicContact CD2-CE1 4.35Å; L138-F497 HydrophobicContact CD2-CG 4.17Å; Y141-F497 HydrophobicContact CD1-CD2 4.5Å; Y141-F497 HydrophobicContact CE1-CD2 4.04Å; V493-F497 HydrophobicContact CG1-CB 4.31Å; N494-F497 HydrophobicContact CB-CD2 3.94Å; N494-F497 HydrophobicContact CB-CE2 4.09Å; N494-F497 PolarHBondContact O-N 3.12Å; L495-F497 VanDerWaalsContact C-N 3.33Å; F497-A499 PolarHBondContact O-N 3.27Å; F497-I500 PolarHBondContact O-N 3.04Å; F497-F501 WeakPolarHBondContact O-CB 3.45Å; F497-F501 PolarHBondContact O-N 2.89Å
498	P	95.2	Very high	91.4	Very high	0 Å²	0	58.9 Å²	58.9	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-60	-31.6	170.9	-22.6	31.3	0	0	0	113.2	C142 T474 L477 F478 V493 N494 L495 L502	C142-P498 VanDerWaalsContact SG-CA 3.54Å; T474-P498 HydrophobicContact CG2-CB 4.02Å; L477-P498 HydrophobicContact CD1-CG 4.05Å; L477-P498 HydrophobicContact CD2-CG 4.11Å; F478-P498 HydrophobicContact CE2-CB 3.63Å; F478-P498 HydrophobicContact CZ-CB 3.71Å; V493-P498 HydrophobicContact CG1-CG 3.69Å; N494-P498 WeakPolarHBondContact O-CD 3.28Å; L495-P498 WeakPolarHBondContact O-CD 3.12Å; P498-L502 WeakPolarHBondContact O-CB 3.41Å; P498-L502 PolarHBondContact O-N 3.39Å
499	A	96.1	Very high	91.3	Very high	36 Å²	36	52 Å²	52	30%	0.298	27%	0.27	S	S	.	.	H	α-helix	trans	-69.1	-46.7	177.5	0	0	0	0	0	111	F478 L495 I496 F497 L502 I503	F478-A499 HydrophobicContact CZ-CB 4.04Å; L495-A499 WeakPolarHBondContact O-CB 3.43Å; L495-A499 PolarHBondContact O-N 3.44Å; L495-A499 VanDerWaalsContact O-N 3.11Å; I496-A499 WeakPolarHBondContact O-CB 3.23Å; I496-A499 PolarHBondContact O-N 3.28Å; F497-A499 PolarHBondContact O-N 3.27Å; A499-L502 PolarHBondContact O-N 2.88Å; A499-I503 VanDerWaalsContact O-CG1 3.27Å; A499-I503 WeakPolarHBondContact O-CG1 3.39Å; A499-I503 PolarHBondContact O-N 3.46Å
500	I	95.5	Very high	91.1	Very high	87 Å²	87	54.1 Å²	54.1	45%	0.446	28%	0.284	S	S	.	.	H	α-helix	trans	-60.1	-47.5	174.9	-66.9	167.2	0	0	0	110.4	L138 I496 F497 L502 I503 G504	L138-I500 HydrophobicContact CD1-CG2 4.31Å; I496-I500 HydrophobicContact CG2-CD1 3.77Å; I496-I500 HydrophobicContact CG2-CG1 4.41Å; I496-I500 WeakPolarHBondContact O-CG1 3.38Å; I496-I500 PolarHBondContact O-N 3.3Å; F497-I500 PolarHBondContact O-N 3.04Å; I500-L502 VanDerWaalsContact C-N 3.34Å; I500-L502 PolarHBondContact O-N 3.39Å; I500-I503 PolarHBondContact O-N 2.91Å; I500-G504 PolarHBondContact O-N 3.01Å
501	F	95.6	Very high	90.8	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-62.8	-41.1	179	-176.2	-111.2	0	0	0	111.9	F135 L138 G139 W318 W467 V470 T474 F497 G504 C505	F135-F501 HydrophobicContact CD1-CD2 4.33Å; F135-F501 AromaticContact CD1-CE2 3.87Å; F135-F501 HydrophobicContact CD1-CE2 3.87Å; F135-F501 AromaticContact CD2-CD2 3.93Å; F135-F501 HydrophobicContact CD2-CD2 3.93Å; F135-F501 HydrophobicContact CD2-CE2 4.3Å; F135-F501 AromaticContact CE1-CD2 3.96Å; F135-F501 HydrophobicContact CE1-CD2 3.96Å; F135-F501 AromaticContact CE1-CE2 3.45Å; F135-F501 HydrophobicContact CE1-CE2 3.45Å; F135-F501 VanDerWaalsContact CE1-CE2 3.45Å; F135-F501 HydrophobicContact CE1-CZ 4.35Å; F135-F501 AromaticContact CE2-CD2 3.48Å; F135-F501 HydrophobicContact CE2-CD2 3.48Å; F135-F501 VanDerWaalsContact CE2-CD2 3.48Å; F135-F501 AromaticContact CE2-CE2 3.9Å; F135-F501 HydrophobicContact CE2-CE2 3.9Å; F135-F501 HydrophobicContact CE2-CG 4.42Å; F135-F501 HydrophobicContact CG-CD2 4.33Å; F135-F501 HydrophobicContact CG-CE2 4.28Å; F135-F501 AromaticContact CZ-CD2 3.5Å; F135-F501 HydrophobicContact CZ-CD2 3.5Å; F135-F501 AromaticContact CZ-CE2 3.46Å; F135-F501 HydrophobicContact CZ-CE2 3.46Å; F135-F501 VanDerWaalsContact CZ-CE2 3.46Å; F135-F501 HydrophobicContact CZ-CG 4.47Å; F135-F501 HydrophobicContact CZ-CZ 4.41Å; F135-F501 WeakPolarHBondContact O-CE2 3.4Å; L138-F501 HydrophobicContact CB-CB 4.38Å; L138-F501 HydrophobicContact CB-CD2 4.17Å; G139-F501 VanDerWaalsContact CA-CE1 3.45Å; G139-F501 VanDerWaalsContact CA-CE2 3.44Å; W318-F501 HydrophobicContact CH2-CE1 4.41Å; W318-F501 HydrophobicContact CH2-CZ 4.12Å; W318-F501 AromaticContact CZ2-CZ 3.96Å; W318-F501 HydrophobicContact CZ2-CZ 3.96Å; W467-F501 HydrophobicContact CZ3-CE2 4.43Å; W467-F501 HydrophobicContact CZ3-CZ 4.12Å; V470-F501 HydrophobicContact CG1-CE1 3.49Å; V470-F501 VanDerWaalsContact CG1-CE1 3.49Å; V470-F501 HydrophobicContact CG1-CZ 3.63Å; T474-F501 HydrophobicContact CG2-CD1 4.02Å; T474-F501 WeakPolarHBondContact OG1-CD1 3.41Å; T474-F501 WeakPolarHBondContact OG1-CE1 3.26Å; F497-F501 WeakPolarHBondContact O-CB 3.45Å; F497-F501 PolarHBondContact O-N 2.89Å; F501-G504 PolarHBondContact O-N 3.37Å; F501-C505 VanDerWaalsContact CE1-SG 3.58Å; F501-C505 PolarHBondContact O-N 3.23Å; F501-C505 PolarHBondContact O-SG 2.64Å
502	L	95.6	Very high	89.9	Confident	35 Å²	35	50.6 Å²	50.6	18%	0.183	26%	0.264	C	S	.	.	H	α-helix	trans	-63.5	-42.6	175.9	-177.4	62.3	0	0	0	111.9	A471 T474 M475 F478 P498 A499 I500 G504 C505 V506	A471-L502 HydrophobicContact CB-CD1 3.83Å; A471-L502 WeakPolarHBondContact O-CD1 3.48Å; T474-L502 HydrophobicContact CG2-CB 4.15Å; M475-L502 HydrophobicContact CG-CD1 3.75Å; M475-L502 HydrophobicContact CG-CD2 3.67Å; M475-L502 HydrophobicContact CG-CG 4.39Å; M475-L502 HydrophobicContact SD-CD1 4.37Å; F478-L502 HydrophobicContact CE2-CD2 4.37Å; P498-L502 WeakPolarHBondContact O-CB 3.41Å; P498-L502 PolarHBondContact O-N 3.39Å; A499-L502 PolarHBondContact O-N 2.88Å; I500-L502 VanDerWaalsContact C-N 3.34Å; I500-L502 PolarHBondContact O-N 3.39Å; L502-G504 VanDerWaalsContact C-N 3.31Å; L502-G504 PolarHBondContact O-N 2.99Å; L502-C505 PolarHBondContact O-N 3.43Å; L502-V506 WeakPolarHBondContact O-CG2 3.37Å; L502-V506 PolarHBondContact O-N 2.88Å
503	I	94.1	Very high	89.4	Confident	119 Å²	119	46.5 Å²	46.5	61%	0.61	25%	0.249	S	C	*	.	H	α-helix	trans	-59.4	-45	174.1	-69	163.6	0	0	0	110.2	A499 I500 C505 V506 F507	A499-I503 VanDerWaalsContact O-CG1 3.27Å; A499-I503 WeakPolarHBondContact O-CG1 3.39Å; A499-I503 PolarHBondContact O-N 3.46Å; I500-I503 PolarHBondContact O-N 2.91Å; I503-C505 PolarHBondContact O-N 2.98Å; I503-V506 PolarHBondContact O-N 3.26Å; I503-F507 PolarHBondContact O-N 3.42Å
504	G	91.4	Very high	88.8	Confident	16 Å²	16	51.8 Å²	51.8	17%	0.165	28%	0.276	C	S	.	.	H	α-helix	trans	-63.4	-39.4	175.9	0	0	0	0	0	113.1	I500 F501 L502 V506 F507 L508	I500-G504 PolarHBondContact O-N 3.01Å; F501-G504 PolarHBondContact O-N 3.37Å; L502-G504 VanDerWaalsContact C-N 3.31Å; L502-G504 PolarHBondContact O-N 2.99Å; G504-V506 VanDerWaalsContact C-N 3.35Å; G504-V506 PolarHBondContact O-N 3.3Å; G504-F507 PolarHBondContact O-N 2.8Å; G504-L508 VanDerWaalsContact O-CG 3.31Å; G504-L508 WeakPolarHBondContact O-CG 3.08Å; G504-L508 PolarHBondContact O-N 3.46Å
505	C	91.1	Very high	87.8	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-62.9	-42	173.8	-65.6	0	0	0	0	111.5	A471 F501 L502 I503 L508 V509	A471-C505 HydrophobicContact CB-CB 3.96Å; F501-C505 VanDerWaalsContact CE1-SG 3.58Å; F501-C505 PolarHBondContact O-N 3.23Å; F501-C505 PolarHBondContact O-SG 2.64Å; L502-C505 PolarHBondContact O-N 3.43Å; I503-C505 PolarHBondContact O-N 2.98Å; C505-L508 PolarHBondContact O-N 3.29Å; C505-V509 VanDerWaalsContact O-CG2 3.32Å; C505-V509 WeakPolarHBondContact O-CG2 3.1Å; C505-V509 PolarHBondContact O-N 3.1Å
506	V	89.7	Confident	86.8	Confident	68 Å²	68	49 Å²	49	41%	0.412	27%	0.266	S	S	.	.	H	α-helix	trans	-64.5	-42.3	176.7	170	0	0	0	0	110.9	L502 I503 G504 V509 I510	L502-V506 WeakPolarHBondContact O-CG2 3.37Å; L502-V506 PolarHBondContact O-N 2.88Å; I503-V506 PolarHBondContact O-N 3.26Å; G504-V506 VanDerWaalsContact C-N 3.35Å; G504-V506 PolarHBondContact O-N 3.3Å; V506-V509 PolarHBondContact O-N 3.04Å; V506-I510 HydrophobicContact CG1-CD1 3.52Å; V506-I510 HydrophobicContact CG1-CG1 4.23Å; V506-I510 WeakPolarHBondContact O-CB 3.23Å; V506-I510 VanDerWaalsContact O-CG1 3.29Å; V506-I510 WeakPolarHBondContact O-CG1 3.24Å; V506-I510 PolarHBondContact O-N 2.74Å
507	F	87.2	Confident	86	Confident	88 Å²	88	47.9 Å²	47.9	39%	0.386	27%	0.265	S	S	.	.	H	α-helix	trans	-58.8	-48.8	173.5	173.4	-96.9	0	0	0	111.5	L308 I503 G504 V509 I510 V511	L308-F507 HydrophobicContact CD1-CE1 4.41Å; I503-F507 PolarHBondContact O-N 3.42Å; G504-F507 PolarHBondContact O-N 2.8Å; F507-V509 VanDerWaalsContact C-N 3.25Å; F507-V509 PolarHBondContact O-N 2.89Å; F507-I510 PolarHBondContact O-N 3.05Å; F507-V511 HydrophobicContact CD1-CG2 4.47Å; F507-V511 HydrophobicContact CD2-CG2 3.77Å; F507-V511 HydrophobicContact CE1-CG2 4.19Å; F507-V511 HydrophobicContact CE2-CG2 3.45Å; F507-V511 VanDerWaalsContact CE2-CG2 3.45Å; F507-V511 HydrophobicContact CG-CG2 4.28Å; F507-V511 HydrophobicContact CZ-CG2 3.69Å; F507-V511 WeakPolarHBondContact O-CG2 3.39Å; F507-V511 PolarHBondContact O-N 2.96Å
508	L	83.5	Confident	85.2	Confident	5 Å²	5	49.2 Å²	49.2	3%	0.026	28%	0.279	C	S	.	.	H	α-helix	trans	-60.7	-36.4	176.8	-70.2	170.1	0	0	0	111.1	F135 Y309 L312 W467 G504 C505 P512	F135-L508 HydrophobicContact CE1-CD1 3.67Å; F135-L508 HydrophobicContact CZ-CD1 4.07Å; Y309-L508 HydrophobicContact CD2-CD2 3.87Å; Y309-L508 HydrophobicContact CE2-CB 4.05Å; Y309-L508 HydrophobicContact CE2-CD2 3.63Å; Y309-L508 HydrophobicContact CE2-CG 4.45Å; Y309-L508 WeakPolarHBondContact CE2-O 3.26Å; Y309-L508 PolarHBondContact OH-O 3.28Å; L312-L508 HydrophobicContact CD1-CD1 3.5Å; L312-L508 VanDerWaalsContact CD1-CD1 3.5Å; L312-L508 HydrophobicContact CD1-CD2 3.97Å; L312-L508 HydrophobicContact CD1-CG 4.39Å; W467-L508 HydrophobicContact CD2-CD1 3.92Å; W467-L508 HydrophobicContact CE3-CD1 4.18Å; W467-L508 HydrophobicContact CG-CB 4.25Å; W467-L508 HydrophobicContact CG-CD1 4.47Å; W467-L508 HydrophobicContact CH2-CD1 4.18Å; W467-L508 HydrophobicContact CZ2-CD1 3.89Å; W467-L508 HydrophobicContact CZ3-CD1 4.3Å; G504-L508 VanDerWaalsContact O-CG 3.31Å; G504-L508 WeakPolarHBondContact O-CG 3.08Å; G504-L508 PolarHBondContact O-N 3.46Å; C505-L508 PolarHBondContact O-N 3.29Å; L508-P512 WeakPolarHBondContact O-CD 3.44Å; L508-P512 WeakPolarHBondContact O-CG 3.43Å
509	V	83	Confident	84	Confident	13 Å²	13	50.2 Å²	50.2	8%	0.079	28%	0.284	C	S	.	.	H	α-helix	trans	-69	-44.9	174.8	170.2	0	0	0	0	112.4	I464 W467 L468 C505 V506 F507 I513	I464-V509 HydrophobicContact CG2-CG1 4.48Å; W467-V509 HydrophobicContact CB-CG2 3.82Å; L468-V509 HydrophobicContact CB-CG2 4.49Å; L468-V509 HydrophobicContact CD1-CG1 4.45Å; L468-V509 HydrophobicContact CD2-CB 4.44Å; L468-V509 HydrophobicContact CD2-CG1 3.72Å; L468-V509 HydrophobicContact CD2-CG2 3.96Å; L468-V509 HydrophobicContact CG-CG1 3.9Å; L468-V509 HydrophobicContact CG-CG2 3.76Å; C505-V509 VanDerWaalsContact O-CG2 3.32Å; C505-V509 WeakPolarHBondContact O-CG2 3.1Å; C505-V509 PolarHBondContact O-N 3.1Å; V506-V509 PolarHBondContact O-N 3.04Å; F507-V509 VanDerWaalsContact C-N 3.25Å; F507-V509 PolarHBondContact O-N 2.89Å; V509-I513 HydrophobicContact CG1-CD1 4.31Å; V509-I513 WeakPolarHBondContact O-CG1 3.43Å
510	I	84.4	Confident	82.9	Confident	85 Å²	85	48.6 Å²	48.6	44%	0.436	27%	0.271	S	S	.	.	H	α-helix	trans	-71.7	-44.1	-171.1	-71.1	172.2	0	0	0	112.6	V506 F507 I513 I514	V506-I510 HydrophobicContact CG1-CD1 3.52Å; V506-I510 HydrophobicContact CG1-CG1 4.23Å; V506-I510 WeakPolarHBondContact O-CB 3.23Å; V506-I510 VanDerWaalsContact O-CG1 3.29Å; V506-I510 WeakPolarHBondContact O-CG1 3.24Å; V506-I510 PolarHBondContact O-N 2.74Å; F507-I510 PolarHBondContact O-N 3.05Å; I510-I513 VanDerWaalsContact O-CB 3.3Å; I510-I513 WeakPolarHBondContact O-CB 3.48Å; I510-I513 WeakPolarHBondContact O-CG1 3.48Å; I510-I513 PolarHBondContact O-N 2.96Å; I510-I513 VanDerWaalsContact O-N 3.09Å; I510-I514 HydrophobicContact CG2-CD1 4.1Å; I510-I514 PolarHBondContact O-N 2.79Å
511	V	79	Confident	82.1	Confident	20 Å²	20	46.6 Å²	46.6	12%	0.121	27%	0.267	C	S	.	.	H	α-helix	trans	-63.1	-43.2	-171.3	-179.3	0	0	0	0	113	S305 F507 I513 I514 A515	S305-V511 VanDerWaalsContact CB-CG1 3.49Å; S305-V511 WeakPolarHBondContact OG-CG1 3.39Å; F507-V511 HydrophobicContact CD1-CG2 4.47Å; F507-V511 HydrophobicContact CD2-CG2 3.77Å; F507-V511 HydrophobicContact CE1-CG2 4.19Å; F507-V511 HydrophobicContact CE2-CG2 3.45Å; F507-V511 VanDerWaalsContact CE2-CG2 3.45Å; F507-V511 HydrophobicContact CG-CG2 4.28Å; F507-V511 HydrophobicContact CZ-CG2 3.69Å; F507-V511 WeakPolarHBondContact O-CG2 3.39Å; F507-V511 PolarHBondContact O-N 2.96Å; V511-I513 VanDerWaalsContact C-N 3.28Å; V511-I513 PolarHBondContact O-N 3.41Å; V511-I514 WeakPolarHBondContact O-CA 3.45Å; V511-I514 WeakPolarHBondContact O-CB 3.41Å; V511-I514 PolarHBondContact O-N 3.32Å; V511-A515 PolarHBondContact O-N 3.13Å
512	P	71	Confident	80.9	Confident	11 Å²	11	47.4 Å²	47.4	7%	0.071	27%	0.271	C	S	.	.	H	α-helix	trans	-63.9	-27.3	173	-24.2	35.2	0	0	0	114.5	Y309 I464 L508 I514 A515 N516 T520	Y309-P512 HydrophobicContact CD2-CG 4.2Å; Y309-P512 HydrophobicContact CE1-CG 4.39Å; Y309-P512 HydrophobicContact CE2-CG 3.35Å; Y309-P512 VanDerWaalsContact CZ-CG 3.48Å; Y309-P512 WeakPolarHBondContact OH-CG 3.33Å; I464-P512 HydrophobicContact CD1-CB 3.67Å; I464-P512 HydrophobicContact CG1-CB 3.92Å; I464-P512 HydrophobicContact CG1-CG 4.27Å; L508-P512 WeakPolarHBondContact O-CD 3.44Å; L508-P512 WeakPolarHBondContact O-CG 3.43Å; P512-I514 PolarHBondContact O-N 3.36Å; P512-A515 PolarHBondContact O-N 3.13Å; P512-N516 CarbonylContact O-C 3.35Å; P512-N516 VanDerWaalsContact O-C 3.31Å; P512-N516 WeakPolarHBondContact O-CA 3.44Å; P512-N516 PolarHBondContact O-N 3.22Å; P512-T520 PolarHBondContact O-OG1 3.21Å; P512-T520 VanDerWaalsContact O-OG1 3.14Å
513	I	78.7	Confident	79.8	Confident	68 Å²	68	45.8 Å²	45.8	35%	0.349	26%	0.263	S	S	.	.	H	α-helix	trans	-59.9	-36.9	172.5	-45	-160.1	0	0	0	109.7	V509 I510 V511 P517 T520	V509-I513 HydrophobicContact CG1-CD1 4.31Å; V509-I513 WeakPolarHBondContact O-CG1 3.43Å; I510-I513 VanDerWaalsContact O-CB 3.3Å; I510-I513 WeakPolarHBondContact O-CB 3.48Å; I510-I513 WeakPolarHBondContact O-CG1 3.48Å; I510-I513 PolarHBondContact O-N 2.96Å; I510-I513 VanDerWaalsContact O-N 3.09Å; V511-I513 VanDerWaalsContact C-N 3.28Å; V511-I513 PolarHBondContact O-N 3.41Å; I513-P517 VanDerWaalsContact O-CA 3.3Å; I513-P517 WeakPolarHBondContact O-CA 3.38Å; I513-P517 WeakPolarHBondContact O-CB 3.34Å; I513-T520 HydrophobicContact CB-CG2 4.02Å; I513-T520 HydrophobicContact CD1-CG2 4.14Å; I513-T520 HydrophobicContact CG1-CG2 3.63Å; I513-T520 HydrophobicContact CG2-CG2 4.09Å
514	I	77	Confident	79.1	Confident	111 Å²	111	42.1 Å²	42.1	57%	0.569	24%	0.244	S	C	*	.	H	α-helix	trans	-80.9	-42.4	179.4	-55.9	170.4	0	0	0	110.5	I510 V511 P512	I510-I514 HydrophobicContact CG2-CD1 4.1Å; I510-I514 PolarHBondContact O-N 2.79Å; V511-I514 WeakPolarHBondContact O-CA 3.45Å; V511-I514 WeakPolarHBondContact O-CB 3.41Å; V511-I514 PolarHBondContact O-N 3.32Å; P512-I514 PolarHBondContact O-N 3.36Å
515	A	72.6	Confident	78.3	Confident	33 Å²	33	46.8 Å²	46.8	27%	0.273	27%	0.265	S	S	.	.	H	α-helix	trans	-74	-43.2	-176.2	0	0	0	0	0	113.1	V511 P512	V511-A515 PolarHBondContact O-N 3.13Å; P512-A515 PolarHBondContact O-N 3.13Å
516	N	73.1	Confident	77.4	Confident	61 Å²	61	47 Å²	47	33%	0.326	27%	0.266	S	S	.	.			trans	-135.1	71.8	-176.8	-68.3	-54.9	0	0	0	110.5	P512 V518 D519 T520	P512-N516 CarbonylContact O-C 3.35Å; P512-N516 VanDerWaalsContact O-C 3.31Å; P512-N516 WeakPolarHBondContact O-CA 3.44Å; P512-N516 PolarHBondContact O-N 3.22Å; N516-V518 VanDerWaalsContact C-N 3.31Å; N516-V518 PolarHBondContact O-N 3.47Å; N516-D519 HydrophobicContact CB-CB 4.39Å; N516-T520 WeakPolarHBondContact O-CB 3.24Å; N516-T520 PolarHBondContact O-N 2.96Å; N516-T520 VanDerWaalsContact O-N 3.12Å; N516-T520 PolarHBondContact O-OG1 3.45Å
517	P	78.3	Confident	76.8	Confident	75 Å²	75	44.8 Å²	44.8	49%	0.487	25%	0.251	S	S	.	.	H	α-helix	trans	-63.5	-33.8	-172.9	22.9	-33.5	0	0	0	113.3	I513 A521	I513-P517 VanDerWaalsContact O-CA 3.3Å; I513-P517 WeakPolarHBondContact O-CA 3.38Å; I513-P517 WeakPolarHBondContact O-CB 3.34Å; P517-A521 VanDerWaalsContact O-CB 3.23Å; P517-A521 WeakPolarHBondContact O-CB 3.26Å; P517-A521 PolarHBondContact O-N 2.99Å
518	V	76.4	Confident	76.5	Confident	102 Å²	102	45.6 Å²	45.6	62%	0.618	26%	0.255	S	S	*	.	H	α-helix	trans	-67.2	-52.8	-178.5	178.4	0	0	0	0	110.8	N516 T520 A521 I522	N516-V518 VanDerWaalsContact C-N 3.31Å; N516-V518 PolarHBondContact O-N 3.47Å; V518-T520 VanDerWaalsContact C-N 3.29Å; V518-T520 PolarHBondContact O-N 3.09Å; V518-A521 WeakPolarHBondContact O-CB 3.47Å; V518-A521 PolarHBondContact O-N 3.4Å; V518-A521 VanDerWaalsContact O-N 3.14Å; V518-I522 HydrophobicContact CG1-CD1 4.03Å; V518-I522 VanDerWaalsContact O-CG1 3.28Å; V518-I522 WeakPolarHBondContact O-CG1 3.25Å; V518-I522 PolarHBondContact O-N 2.89Å
519	D	69.9	Low	76.3	Confident	22 Å²	22	47.4 Å²	47.4	12%	0.118	27%	0.266	C	S	.	.	H	α-helix	trans	-60.8	-41.5	178.9	-74.6	-27.5	0	0	0	111.6	Y183 C461 N516 I522 G523	Y183-D519 PolarHBondContact OH-OD1 3.41Å; C461-D519 VanDerWaalsContact SG-CB 3.59Å; C461-D519 PolarHBondContact SG-O 3.49Å; C461-D519 VanDerWaalsContact SG-O 3.34Å; N516-D519 HydrophobicContact CB-CB 4.39Å; D519-I522 PolarHBondContact O-N 2.72Å; D519-G523 PolarHBondContact O-N 2.94Å
520	T	74.7	Confident	76.1	Confident	1 Å²	1	46.8 Å²	46.8	1%	0.006	26%	0.262	C	S	.	.	H	α-helix	trans	-58.6	-49.7	173	-58.3	0	0	0	0	111.5	I464 P512 I513 N516 V518 I522 G523 L524	I464-T520 HydrophobicContact CD1-CG2 4.09Å; I464-T520 WeakPolarHBondContact CD1-OG1 3.5Å; I464-T520 HydrophobicContact CG2-CG2 4.47Å; P512-T520 PolarHBondContact O-OG1 3.21Å; P512-T520 VanDerWaalsContact O-OG1 3.14Å; I513-T520 HydrophobicContact CB-CG2 4.02Å; I513-T520 HydrophobicContact CD1-CG2 4.14Å; I513-T520 HydrophobicContact CG1-CG2 3.63Å; I513-T520 HydrophobicContact CG2-CG2 4.09Å; N516-T520 WeakPolarHBondContact O-CB 3.24Å; N516-T520 PolarHBondContact O-N 2.96Å; N516-T520 VanDerWaalsContact O-N 3.12Å; N516-T520 PolarHBondContact O-OG1 3.45Å; V518-T520 VanDerWaalsContact C-N 3.29Å; V518-T520 PolarHBondContact O-N 3.09Å; T520-I522 VanDerWaalsContact C-N 3.28Å; T520-I522 PolarHBondContact O-N 2.94Å; T520-G523 PolarHBondContact O-N 3.49Å; T520-L524 HydrophobicContact CG2-CD1 4Å; T520-L524 HydrophobicContact CG2-CG 4.36Å; T520-L524 WeakPolarHBondContact O-CG 3.39Å; T520-L524 PolarHBondContact O-N 3.44Å
521	A	77.4	Confident	76	Confident	45 Å²	45	45.5 Å²	45.5	37%	0.372	26%	0.256	S	S	.	.	H	α-helix	trans	-60	-41.2	-179.7	0	0	0	0	0	110.9	P517 V518 L524 L525	P517-A521 VanDerWaalsContact O-CB 3.23Å; P517-A521 WeakPolarHBondContact O-CB 3.26Å; P517-A521 PolarHBondContact O-N 2.99Å; V518-A521 WeakPolarHBondContact O-CB 3.47Å; V518-A521 PolarHBondContact O-N 3.4Å; V518-A521 VanDerWaalsContact O-N 3.14Å; A521-L524 PolarHBondContact O-N 3.28Å; A521-L525 WeakPolarHBondContact O-CB 3.41Å; A521-L525 WeakPolarHBondContact O-CG 3.26Å; A521-L525 PolarHBondContact O-N 3.39Å
522	I	71.4	Confident	76	Confident	17 Å²	17	47.7 Å²	47.7	9%	0.087	27%	0.271	C	S	.	.	H	α-helix	trans	-62.7	-49.5	175.7	-60.6	166	0	0	0	110.3	Y183 V186 V518 D519 T520 L524 L525 I526	Y183-I522 HydrophobicContact CD2-CB 4.24Å; Y183-I522 HydrophobicContact CD2-CG2 3.38Å; Y183-I522 HydrophobicContact CE2-CB 4.03Å; Y183-I522 HydrophobicContact CE2-CD1 3.98Å; Y183-I522 HydrophobicContact CE2-CG2 3.64Å; Y183-I522 HydrophobicContact CG-CG2 4.47Å; V186-I522 HydrophobicContact CB-CG2 4.34Å; V186-I522 HydrophobicContact CG1-CD1 4.09Å; V186-I522 HydrophobicContact CG1-CG1 4.01Å; V186-I522 HydrophobicContact CG1-CG2 4.13Å; V186-I522 HydrophobicContact CG2-CG2 4.45Å; V518-I522 HydrophobicContact CG1-CD1 4.03Å; V518-I522 VanDerWaalsContact O-CG1 3.28Å; V518-I522 WeakPolarHBondContact O-CG1 3.25Å; V518-I522 PolarHBondContact O-N 2.89Å; D519-I522 PolarHBondContact O-N 2.72Å; T520-I522 VanDerWaalsContact C-N 3.28Å; T520-I522 PolarHBondContact O-N 2.94Å; I522-L524 VanDerWaalsContact C-N 3.3Å; I522-L524 PolarHBondContact O-N 3.19Å; I522-L525 PolarHBondContact O-N 2.83Å; I522-I526 HydrophobicContact CG2-CD1 3.7Å; I522-I526 HydrophobicContact CG2-CG1 4.27Å; I522-I526 WeakPolarHBondContact O-CG1 3.38Å; I522-I526 PolarHBondContact O-N 3.26Å
523	G	71.2	Confident	76.1	Confident	1 Å²	1	49 Å²	49	1%	0.01	28%	0.279	C	S	.	.	H	α-helix	trans	-56.3	-42.9	177.4	0	0	0	0	0	112.9	D519 T520 I526 M527	D519-G523 PolarHBondContact O-N 2.94Å; T520-G523 PolarHBondContact O-N 3.49Å; G523-I526 PolarHBondContact O-N 3.3Å; G523-M527 PolarHBondContact O-N 3.4Å
524	L	79.3	Confident	76	Confident	42 Å²	42	47.2 Å²	47.2	22%	0.22	27%	0.268	C	S	.	.	H	α-helix	trans	-68.2	-43.2	176.4	-68.3	176.7	0	0	0	112.7	L468 T520 A521 I522 I526 M527 F528	L468-L524 HydrophobicContact CD1-CD2 3.69Å; T520-L524 HydrophobicContact CG2-CD1 4Å; T520-L524 HydrophobicContact CG2-CG 4.36Å; T520-L524 WeakPolarHBondContact O-CG 3.39Å; T520-L524 PolarHBondContact O-N 3.44Å; A521-L524 PolarHBondContact O-N 3.28Å; I522-L524 VanDerWaalsContact C-N 3.3Å; I522-L524 PolarHBondContact O-N 3.19Å; L524-I526 VanDerWaalsContact C-N 3.28Å; L524-I526 PolarHBondContact O-N 3.1Å; L524-M527 HydrophobicContact CD2-CE 3.49Å; L524-M527 VanDerWaalsContact CD2-CE 3.49Å; L524-M527 WeakPolarHBondContact O-CB 3.44Å; L524-M527 PolarHBondContact O-N 2.97Å; L524-F528 HydrophobicContact CB-CD2 4.47Å; L524-F528 HydrophobicContact CB-CE2 4.25Å; L524-F528 WeakPolarHBondContact O-CD2 3.16Å; L524-F528 WeakPolarHBondContact O-CG 3.46Å; L524-F528 PolarHBondContact O-N 3.39Å
525	L	76.3	Confident	76	Confident	114 Å²	114	45.1 Å²	45.1	60%	0.597	26%	0.257	S	S	*	.	H	α-helix	trans	-58.7	-44.2	175.8	-76.9	170.8	0	0	0	110.7	A521 I522 F528 T529	A521-L525 WeakPolarHBondContact O-CB 3.41Å; A521-L525 WeakPolarHBondContact O-CG 3.26Å; A521-L525 PolarHBondContact O-N 3.39Å; I522-L525 PolarHBondContact O-N 2.83Å; L525-F528 PolarHBondContact O-N 2.87Å; L525-F528 VanDerWaalsContact O-N 3.12Å; L525-T529 WeakPolarHBondContact O-CG2 3.47Å; L525-T529 PolarHBondContact O-N 3.23Å
526	I	70.6	Confident	75.9	Confident	4 Å²	4	48.6 Å²	48.6	2%	0.021	27%	0.27	C	S	.	.	H	α-helix	trans	-63.7	-43.7	177.4	-61.9	169.1	0	0	0	110.6	I178 L179 L182 Y183 I522 G523 L524 F528 T529	I178-I526 HydrophobicContact CG2-CG2 4.24Å; L179-I526 HydrophobicContact CB-CG2 4.49Å; L179-I526 HydrophobicContact CD1-CB 4.04Å; L179-I526 HydrophobicContact CD1-CG2 3.84Å; L179-I526 HydrophobicContact CG-CG2 4.29Å; L179-I526 WeakPolarHBondContact O-CD1 3.3Å; L182-I526 HydrophobicContact CB-CD1 3.97Å; L182-I526 HydrophobicContact CB-CG1 3.73Å; L182-I526 HydrophobicContact CB-CG2 4.14Å; L182-I526 HydrophobicContact CD1-CG1 4.39Å; L182-I526 HydrophobicContact CD1-CG2 3.95Å; Y183-I526 HydrophobicContact CD2-CD1 4.24Å; I522-I526 HydrophobicContact CG2-CD1 3.7Å; I522-I526 HydrophobicContact CG2-CG1 4.27Å; I522-I526 WeakPolarHBondContact O-CG1 3.38Å; I522-I526 PolarHBondContact O-N 3.26Å; G523-I526 PolarHBondContact O-N 3.3Å; L524-I526 VanDerWaalsContact C-N 3.28Å; L524-I526 PolarHBondContact O-N 3.1Å; I526-F528 VanDerWaalsContact C-N 3.29Å; I526-F528 PolarHBondContact O-N 3.05Å; I526-T529 PolarHBondContact O-N 3.47Å; I526-T529 PolarHBondContact O-OG1 3.3Å
527	M	77.3	Confident	75.7	Confident	22 Å²	22	47.9 Å²	47.9	11%	0.108	27%	0.27	C	S	.	.	H	α-helix	trans	-56	-44	171.8	172.3	178.9	71.1	0	0	111.7	I171 I175 V465 L468 G523 L524 T529 S530	I171-M527 HydrophobicContact CG2-CG 3.69Å; I171-M527 HydrophobicContact CG2-SD 4.26Å; I175-M527 HydrophobicContact CD1-CB 4.38Å; I175-M527 HydrophobicContact CD1-CG 3.69Å; I175-M527 HydrophobicContact CD1-SD 3.81Å; I175-M527 HydrophobicContact CG1-CB 4.02Å; I175-M527 HydrophobicContact CG1-CG 3.78Å; I175-M527 HydrophobicContact CG1-SD 4.48Å; V465-M527 HydrophobicContact CG1-CB 4.26Å; V465-M527 HydrophobicContact CG1-CG 4.49Å; V465-M527 HydrophobicContact CG1-SD 4.15Å; L468-M527 HydrophobicContact CD1-CE 4.25Å; L468-M527 HydrophobicContact CD1-SD 4.38Å; G523-M527 PolarHBondContact O-N 3.4Å; L524-M527 HydrophobicContact CD2-CE 3.49Å; L524-M527 VanDerWaalsContact CD2-CE 3.49Å; L524-M527 WeakPolarHBondContact O-CB 3.44Å; L524-M527 PolarHBondContact O-N 2.97Å; M527-T529 VanDerWaalsContact C-N 3.3Å; M527-T529 PolarHBondContact O-N 2.89Å; M527-S530 VanDerWaalsContact O-CB 3.23Å; M527-S530 WeakPolarHBondContact O-CB 3.2Å; M527-S530 PolarHBondContact O-N 3.36Å; M527-S530 PolarHBondContact O-OG 3.29Å
528	F	82.2	Confident	75.2	Confident	106 Å²	106	45.5 Å²	45.5	47%	0.465	25%	0.253	S	S	.	.	H	α-helix	trans	-72.8	-16.1	-178.4	-70	-51.8	0	0	0	114.6	L524 L525 I526 S530 I531 P532	L524-F528 HydrophobicContact CB-CD2 4.47Å; L524-F528 HydrophobicContact CB-CE2 4.25Å; L524-F528 WeakPolarHBondContact O-CD2 3.16Å; L524-F528 WeakPolarHBondContact O-CG 3.46Å; L524-F528 PolarHBondContact O-N 3.39Å; L525-F528 PolarHBondContact O-N 2.87Å; L525-F528 VanDerWaalsContact O-N 3.12Å; I526-F528 VanDerWaalsContact C-N 3.29Å; I526-F528 PolarHBondContact O-N 3.05Å; F528-S530 PolarHBondContact O-N 2.93Å; F528-S530 VanDerWaalsContact O-N 3.12Å; F528-I531 HydrophobicContact CB-CD1 4.46Å; F528-I531 HydrophobicContact CD1-CD1 3.77Å; F528-I531 WeakPolarHBondContact O-CB 3.46Å; F528-I531 WeakPolarHBondContact O-CG1 3.36Å; F528-I531 PolarHBondContact O-N 3.32Å; F528-P532 WeakPolarHBondContact O-CD 2.88Å
529	T	78.1	Confident	74.7	Confident	42 Å²	42	49.3 Å²	49.3	26%	0.258	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.3	-17.1	168.7	67.7	0	0	0	0	113.3	W174 L182 L525 I526 M527 I531 P532	W174-T529 PolarHBondContact NE1-OG1 3.28Å; L182-T529 HydrophobicContact CD1-CG2 3.65Å; L525-T529 WeakPolarHBondContact O-CG2 3.47Å; L525-T529 PolarHBondContact O-N 3.23Å; I526-T529 PolarHBondContact O-N 3.47Å; I526-T529 PolarHBondContact O-OG1 3.3Å; M527-T529 VanDerWaalsContact C-N 3.3Å; M527-T529 PolarHBondContact O-N 2.89Å; T529-I531 PolarHBondContact O-N 2.83Å; T529-P532 VanDerWaalsContact O-CD 3.25Å; T529-P532 WeakPolarHBondContact O-CD 3.49Å; T529-P532 VanDerWaalsContact O-CG 3.29Å; T529-P532 WeakPolarHBondContact O-CG 3.42Å
530	S	79.9	Confident	74.1	Confident	0 Å²	0	54.4 Å²	54.4	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-59.3	-31.7	170.2	60.1	0	0	0	0	113	F170 I171 W174 M527 F528 V533 Y534	F170-S530 WeakPolarHBondContact CE1-O 3.43Å; I171-S530 WeakPolarHBondContact CG1-OG 3.48Å; W174-S530 VanDerWaalsContact CD1-CA 3.48Å; W174-S530 VanDerWaalsContact NE1-N 3.19Å; M527-S530 VanDerWaalsContact O-CB 3.23Å; M527-S530 WeakPolarHBondContact O-CB 3.2Å; M527-S530 PolarHBondContact O-N 3.36Å; M527-S530 PolarHBondContact O-OG 3.29Å; F528-S530 PolarHBondContact O-N 2.93Å; F528-S530 VanDerWaalsContact O-N 3.12Å; S530-V533 PolarHBondContact O-N 3.09Å; S530-Y534 VanDerWaalsContact O-CB 3.3Å; S530-Y534 WeakPolarHBondContact O-CB 3.38Å; S530-Y534 PolarHBondContact O-N 2.86Å
531	I	81.9	Confident	73.3	Confident	58 Å²	58	61 Å²	61	30%	0.297	30%	0.302	S	S	.	.	H	α-helix	trans	-63.8	-56.9	-173.8	-58.6	179.4	0	0	0	111.8	F167 F528 T529 V533 Y534 I535	F167-I531 HydrophobicContact CE2-CG1 4.44Å; F167-I531 HydrophobicContact CZ-CG1 4.07Å; F528-I531 HydrophobicContact CB-CD1 4.46Å; F528-I531 HydrophobicContact CD1-CD1 3.77Å; F528-I531 WeakPolarHBondContact O-CB 3.46Å; F528-I531 WeakPolarHBondContact O-CG1 3.36Å; F528-I531 PolarHBondContact O-N 3.32Å; T529-I531 PolarHBondContact O-N 2.83Å; I531-V533 VanDerWaalsContact C-N 3.26Å; I531-V533 PolarHBondContact O-N 3.08Å; I531-Y534 PolarHBondContact O-N 3.24Å; I531-I535 HydrophobicContact CG2-CD1 3.94Å; I531-I535 WeakPolarHBondContact O-CG1 3.01Å; I531-I535 PolarHBondContact O-N 3.2Å
532	P	77.8	Confident	72.1	Confident	67 Å²	67	61.4 Å²	61.4	44%	0.435	30%	0.301	S	S	.	.	H	α-helix	trans	-60	-38.1	178.8	22	-33.2	0	0	0	111.9	F528 T529 I535 L536	F528-P532 WeakPolarHBondContact O-CD 2.88Å; T529-P532 VanDerWaalsContact O-CD 3.25Å; T529-P532 WeakPolarHBondContact O-CD 3.49Å; T529-P532 VanDerWaalsContact O-CG 3.29Å; T529-P532 WeakPolarHBondContact O-CG 3.42Å; P532-I535 PolarHBondContact O-N 3.15Å; P532-L536 WeakPolarHBondContact O-CB 3.29Å; P532-L536 VanDerWaalsContact O-CG 3.29Å; P532-L536 WeakPolarHBondContact O-CG 3.31Å; P532-L536 PolarHBondContact O-N 3.16Å
533	V	74.9	Confident	70.9	Confident	39 Å²	39	69.3 Å²	69.3	24%	0.236	33%	0.334	C	S	.	.	H	α-helix	trans	-70.3	-38.4	-179.7	-178	0	0	0	0	112.1	F170 W174 S530 I531 I535 L536 C537	F170-V533 HydrophobicContact CZ-CG1 4.26Å; W174-V533 HydrophobicContact CE3-CG1 4.32Å; W174-V533 HydrophobicContact CH2-CB 3.52Å; W174-V533 HydrophobicContact CH2-CG1 3.41Å; W174-V533 VanDerWaalsContact CH2-CG1 3.41Å; W174-V533 HydrophobicContact CH2-CG2 3.4Å; W174-V533 HydrophobicContact CZ2-CB 3.9Å; W174-V533 HydrophobicContact CZ2-CG1 4.3Å; W174-V533 HydrophobicContact CZ2-CG2 3.55Å; W174-V533 HydrophobicContact CZ3-CB 3.87Å; W174-V533 HydrophobicContact CZ3-CG1 3.42Å; W174-V533 VanDerWaalsContact CZ3-CG1 3.42Å; W174-V533 HydrophobicContact CZ3-CG2 4.26Å; S530-V533 PolarHBondContact O-N 3.09Å; I531-V533 VanDerWaalsContact C-N 3.26Å; I531-V533 PolarHBondContact O-N 3.08Å; V533-I535 VanDerWaalsContact C-N 3.31Å; V533-I535 PolarHBondContact O-N 2.99Å; V533-L536 PolarHBondContact O-N 3.16Å; V533-C537 HydrophobicContact CG1-CB 4.25Å; V533-C537 VanDerWaalsContact O-CB 3.31Å; V533-C537 WeakPolarHBondContact O-CB 3.45Å; V533-C537 PolarHBondContact O-N 3.33Å
534	Y	76	Confident	69.8	Low	30 Å²	30	72.4 Å²	72.4	12%	0.118	36%	0.36	C	S	.	.	I	π-helix	trans	-59	-45.2	172.1	-174.5	-97.2	0	0	0	111.3	F167 F170 S530 I531 I538 W539	F167-Y534 HydrophobicContact CB-CE1 4.15Å; F167-Y534 AromaticContact CD2-CD1 3.46Å; F167-Y534 HydrophobicContact CD2-CD1 3.46Å; F167-Y534 VanDerWaalsContact CD2-CD1 3.46Å; F167-Y534 HydrophobicContact CD2-CD2 4.28Å; F167-Y534 AromaticContact CD2-CE1 3.67Å; F167-Y534 HydrophobicContact CD2-CE1 3.67Å; F167-Y534 HydrophobicContact CD2-CE2 4.45Å; F167-Y534 AromaticContact CD2-CG 3.77Å; F167-Y534 HydrophobicContact CD2-CG 3.77Å; F167-Y534 HydrophobicContact CE2-CD1 4.01Å; F167-Y534 HydrophobicContact CE2-CG 4.24Å; F167-Y534 HydrophobicContact CG-CE1 4.36Å; F170-Y534 HydrophobicContact CB-CD2 3.58Å; F170-Y534 HydrophobicContact CB-CE2 3.82Å; F170-Y534 AromaticContact CD1-CD2 3.48Å; F170-Y534 HydrophobicContact CD1-CD2 3.48Å; F170-Y534 VanDerWaalsContact CD1-CD2 3.48Å; F170-Y534 HydrophobicContact CD1-CG 4.01Å; F170-Y534 HydrophobicContact CD2-CD2 4.33Å; F170-Y534 HydrophobicContact CE1-CD2 4.2Å; F170-Y534 HydrophobicContact CE1-CG 4.5Å; F170-Y534 AromaticContact CG-CD2 3.52Å; F170-Y534 HydrophobicContact CG-CD2 3.52Å; F170-Y534 HydrophobicContact CG-CE2 4.22Å; F170-Y534 HydrophobicContact CG-CG 4.47Å; S530-Y534 VanDerWaalsContact O-CB 3.3Å; S530-Y534 WeakPolarHBondContact O-CB 3.38Å; S530-Y534 PolarHBondContact O-N 2.86Å; I531-Y534 PolarHBondContact O-N 3.24Å; Y534-I538 HydrophobicContact CD2-CB 3.98Å; Y534-I538 HydrophobicContact CD2-CD1 3.73Å; Y534-I538 HydrophobicContact CD2-CG1 4.44Å; Y534-I538 HydrophobicContact CD2-CG2 4.09Å; Y534-I538 HydrophobicContact CE2-CB 4.09Å; Y534-I538 HydrophobicContact CE2-CD1 4.14Å; Y534-I538 HydrophobicContact CE2-CG2 3.67Å; Y534-I538 WeakPolarHBondContact O-CA 3.5Å; Y534-I538 WeakPolarHBondContact O-CB 3.25Å; Y534-I538 PolarHBondContact O-N 2.97Å; Y534-I538 VanDerWaalsContact O-N 3.09Å; Y534-W539 HydrophobicContact CD1-CB 4.41Å; Y534-W539 HydrophobicContact CE1-CB 4.3Å; Y534-W539 PolarHBondContact O-N 3.25Å
535	I	77	Confident	68.2	Low	67 Å²	67	74.8 Å²	74.8	34%	0.344	37%	0.369	S	S	.	.	I	π-helix	trans	-63.3	-44.5	-179.7	-68.1	169.6	0	0	0	110.9	I531 P532 V533 W539 K540	I531-I535 HydrophobicContact CG2-CD1 3.94Å; I531-I535 WeakPolarHBondContact O-CG1 3.01Å; I531-I535 PolarHBondContact O-N 3.2Å; P532-I535 PolarHBondContact O-N 3.15Å; V533-I535 VanDerWaalsContact C-N 3.31Å; V533-I535 PolarHBondContact O-N 2.99Å; I535-W539 HydrophobicContact CG2-CE3 4.09Å; I535-K540 WeakPolarHBondContact O-CB 3.31Å; I535-K540 PolarHBondContact O-N 3.11Å
536	L	71.2	Confident	66.8	Low	106 Å²	106	72.4 Å²	72.4	56%	0.555	36%	0.362	S	S	*	.	I	π-helix	trans	-78.9	-44.6	-174.8	-69.3	172.9	0	0	0	113.5	P532 V533 K540	P532-L536 WeakPolarHBondContact O-CB 3.29Å; P532-L536 VanDerWaalsContact O-CG 3.29Å; P532-L536 WeakPolarHBondContact O-CG 3.31Å; P532-L536 PolarHBondContact O-N 3.16Å; V533-L536 PolarHBondContact O-N 3.16Å; L536-K540 VanDerWaalsContact O-O 3.07Å
537	C	67.3	Low	65.5	Low	46 Å²	46	79.3 Å²	79.3	31%	0.311	39%	0.391	S	S	.	.	I	π-helix	trans	-94.2	-34	-170.7	-65.4	0	0	0	0	112.9	V533	V533-C537 HydrophobicContact CG1-CB 4.25Å; V533-C537 VanDerWaalsContact O-CB 3.31Å; V533-C537 WeakPolarHBondContact O-CB 3.45Å; V533-C537 PolarHBondContact O-N 3.33Å
538	I	68.1	Low	64	Low	25 Å²	25	83.4 Å²	83.4	13%	0.128	41%	0.413	C	S	.	.	I	π-helix	trans	-106.3	-51.2	-171.5	-63.5	168.9	0	0	0	111.5	F170 H419 Y534 R541	F170-I538 HydrophobicContact CD1-CD1 4.34Å; F170-I538 HydrophobicContact CD2-CD1 3.2Å; F170-I538 HydrophobicContact CE1-CD1 4.33Å; F170-I538 HydrophobicContact CE2-CD1 3.21Å; F170-I538 HydrophobicContact CG-CD1 3.79Å; F170-I538 HydrophobicContact CZ-CD1 3.78Å; H419-I538 HydrophobicContact CB-CD1 4.34Å; Y534-I538 HydrophobicContact CD2-CB 3.98Å; Y534-I538 HydrophobicContact CD2-CD1 3.73Å; Y534-I538 HydrophobicContact CD2-CG1 4.44Å; Y534-I538 HydrophobicContact CD2-CG2 4.09Å; Y534-I538 HydrophobicContact CE2-CB 4.09Å; Y534-I538 HydrophobicContact CE2-CD1 4.14Å; Y534-I538 HydrophobicContact CE2-CG2 3.67Å; Y534-I538 WeakPolarHBondContact O-CA 3.5Å; Y534-I538 WeakPolarHBondContact O-CB 3.25Å; Y534-I538 PolarHBondContact O-N 2.97Å; Y534-I538 VanDerWaalsContact O-N 3.09Å; I538-R541 WeakPolarHBondContact O-CG 3.43Å
539	W	66.3	Low	62.3	Low	182 Å²	182	79.9 Å²	79.9	69%	0.689	40%	0.401	S	S	*	.	I	π-helix	trans	-73.1	-50.9	-177.3	-172.6	63.5	0	0	0	111.7	Y534 I535 R541	Y534-W539 HydrophobicContact CD1-CB 4.41Å; Y534-W539 HydrophobicContact CE1-CB 4.3Å; Y534-W539 PolarHBondContact O-N 3.25Å; I535-W539 HydrophobicContact CG2-CE3 4.09Å; W539-R541 PolarHBondContact O-N 3.29Å
540	K	58.7	Low	60.6	Low	128 Å²	128	81.4 Å²	81.4	56%	0.557	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.1	61.4	172	-66.3	-173.8	179.1	-178.7	0	110.9	I535 L536 P542	I535-K540 WeakPolarHBondContact O-CB 3.31Å; I535-K540 PolarHBondContact O-N 3.11Å; L536-K540 VanDerWaalsContact O-O 3.07Å; K540-P542 WeakPolarHBondContact O-CD 3.28Å; K540-P542 WeakPolarHBondContact O-CG 3.5Å
541	R	56.8	Low	59	Low	140 Å²	140	90.3 Å²	90.3	53%	0.528	45%	0.453	S	S	.	.			trans	-48.2	105.8	-179.2	-73.4	-148	176	-173.6	-1.1	111.6	G418 I538 W539	G418-R541 PolarHBondContact O-NH2 3.42Å; I538-R541 WeakPolarHBondContact O-CG 3.43Å; W539-R541 PolarHBondContact O-N 3.29Å
542	P	52.3	Low	57.2	Low	54 Å²	54	89.2 Å²	89.2	35%	0.351	45%	0.45	S	S	.	.			trans	-69.2	141.5	179.7	-14.9	30.1	0	0	0	108.2	K540 A544 F545 S546	K540-P542 WeakPolarHBondContact O-CD 3.28Å; K540-P542 WeakPolarHBondContact O-CG 3.5Å; P542-A544 PolarHBondContact O-N 3.49Å; P542-F545 PolarHBondContact O-N 2.72Å; P542-S546 PolarHBondContact O-N 2.96Å
543	K	47	Very low	55.2	Low	182 Å²	182	90.4 Å²	90.4	79%	0.791	45%	0.452	S	S	*	.	H	α-helix	trans	-54.8	-21.3	176.3	-67.1	-177.7	179.8	177.7	0	113.1	S546 K547	K543-S546 PolarHBondContact O-N 3.44Å; K543-S546 PolarHBondContact O-OG 3.38Å; K543-K547 PolarHBondContact O-N 2.94Å; K543-K547 VanDerWaalsContact O-N 3.13Å
544	A	46.6	Very low	53.4	Low	66 Å²	66	94.1 Å²	94.1	55%	0.545	48%	0.477	S	S	.	.	H	α-helix	trans	-65	-42.8	173.9	0	0	0	0	0	112.6	P542 S546 K547 L548	P542-A544 PolarHBondContact O-N 3.49Å; A544-S546 VanDerWaalsContact C-N 3.34Å; A544-S546 PolarHBondContact O-N 2.97Å; A544-K547 PolarHBondContact O-N 3.02Å; A544-L548 PolarHBondContact O-N 2.82Å; A544-L548 VanDerWaalsContact O-N 3.12Å
545	F	47.2	Very low	51.3	Low	93 Å²	93	96.7 Å²	96.7	41%	0.408	50%	0.5	S	S	.	.	H	α-helix	trans	-67.3	-35.5	176.1	-102.5	-85.2	0	0	0	111.7	P542 K547 L548 S549	P542-F545 PolarHBondContact O-N 2.72Å; F545-K547 VanDerWaalsContact C-N 3.29Å; F545-K547 PolarHBondContact O-N 2.86Å; F545-L548 PolarHBondContact O-N 2.84Å; F545-S549 WeakPolarHBondContact O-CB 3.44Å; F545-S549 PolarHBondContact O-N 2.69Å
546	S	46.7	Very low	49	Very low	64 Å²	64	102.8 Å²	102.8	45%	0.448	53%	0.527	S	S	.	.	H	α-helix	trans	-66.2	-31.8	174	79.2	0	0	0	0	112.3	P542 K543 A544 S550	P542-S546 PolarHBondContact O-N 2.96Å; K543-S546 PolarHBondContact O-N 3.44Å; K543-S546 PolarHBondContact O-OG 3.38Å; A544-S546 VanDerWaalsContact C-N 3.34Å; A544-S546 PolarHBondContact O-N 2.97Å; S546-S550 VanDerWaalsContact O-CB 3.32Å; S546-S550 WeakPolarHBondContact O-CB 3.49Å; S546-S550 PolarHBondContact O-N 3.49Å; S546-S550 PolarHBondContact O-OG 3.02Å
547	K	43.3	Very low	46.9	Very low	148 Å²	148	105.4 Å²	105.4	64%	0.643	53%	0.534	S	S	*	.	H	α-helix	trans	-71.4	-40.4	175.3	-84.1	-175.9	176.6	-178.6	0	113.4	K543 A544 F545 S549 S550 K551	K543-K547 PolarHBondContact O-N 2.94Å; K543-K547 VanDerWaalsContact O-N 3.13Å; A544-K547 PolarHBondContact O-N 3.02Å; F545-K547 VanDerWaalsContact C-N 3.29Å; F545-K547 PolarHBondContact O-N 2.86Å; K547-S549 VanDerWaalsContact C-N 3.33Å; K547-S550 PolarHBondContact O-OG 3.07Å; K547-K551 WeakPolarHBondContact O-CB 3.31Å; K547-K551 PolarHBondContact O-N 2.91Å
548	L	44.6	Very low	45	Very low	109 Å²	109	115.5 Å²	115.5	57%	0.571	58%	0.576	S	S	*	*	H	α-helix	trans	-64.9	-42.3	174.2	-118.6	99.3	0	0	0	110.7	A544 F545 S552	A544-L548 PolarHBondContact O-N 2.82Å; A544-L548 VanDerWaalsContact O-N 3.12Å; F545-L548 PolarHBondContact O-N 2.84Å; L548-S552 PolarHBondContact O-N 2.89Å
549	S	46.5	Very low	43.9	Very low	31 Å²	31	120 Å²	120	22%	0.217	60%	0.598	C	S	.	*	H	α-helix	trans	-58.1	-51.3	173.1	153.4	0	0	0	0	111.8	Q422 F545 K547 K551 S552	Q422-S549 PolarHBondContact NE2-OG 3.48Å; Q422-S549 PolarHBondContact OE1-OG 3.41Å; F545-S549 WeakPolarHBondContact O-CB 3.44Å; F545-S549 PolarHBondContact O-N 2.69Å; K547-S549 VanDerWaalsContact C-N 3.33Å; S549-K551 PolarHBondContact O-N 3.06Å; S549-S552 PolarHBondContact O-N 3.26Å; S549-S552 PolarHBondContact O-OG 3.28Å
550	S	43.8	Very low	42.7	Very low	74 Å²	74	116.7 Å²	116.7	52%	0.517	59%	0.593	S	S	.	*	H	α-helix	trans	-71.8	-25.4	-176.8	73.4	0	0	0	0	114.2	S546 K547	S546-S550 VanDerWaalsContact O-CB 3.32Å; S546-S550 WeakPolarHBondContact O-CB 3.49Å; S546-S550 PolarHBondContact O-N 3.49Å; S546-S550 PolarHBondContact O-OG 3.02Å; K547-S550 PolarHBondContact O-OG 3.07Å
551	K	45.3	Very low	41.8	Very low	187 Å²	187	116.1 Å²	116.1	81%	0.813	60%	0.595	S	S	*	*	H	α-helix	trans	-76.2	-25.3	174.5	-84.2	-172.5	174.4	-172.9	0	112.8	K547 S549	K547-K551 WeakPolarHBondContact O-CB 3.31Å; K547-K551 PolarHBondContact O-N 2.91Å; S549-K551 PolarHBondContact O-N 3.06Å
552	S	44.8	Very low	40.9	Very low	35 Å²	35	114.7 Å²	114.7	25%	0.245	60%	0.599	C	S	.	*	H	α-helix	trans	-80.1	-18.9	-178.9	68.6	0	0	0	0	113.9	L548 S549	L548-S552 PolarHBondContact O-N 2.89Å; S549-S552 PolarHBondContact O-N 3.26Å; S549-S552 PolarHBondContact O-OG 3.28Å
553	L	35.9	Very low	40.2	Very low	93 Å²	93	118.5 Å²	118.5	49%	0.487	62%	0.615	S	S	.	*	S	Bend	trans	-93	127.9	161.5	-93.5	80.7	0	0	0	108.2	S555	L553-S555 PolarHBondContact O-N 3.42Å
554	P	36	Very low	39.7	Very low	117 Å²	117	114.3 Å²	114.3	76%	0.76	60%	0.603	S	S	*	*	P	Polyproline II helix	trans	-52	121.4	155.4	-12.8	25.6	0	0	0	105.4	Q556	P554-Q556 PolarHBondContact O-N 3.07Å
555	S	31.8	Very low	39.3	Very low	84 Å²	84	117.7 Å²	117.7	59%	0.587	61%	0.607	S	S	*	*	P	Polyproline II helix	trans	-47.5	118.6	169.8	54	0	0	0	0	106.3	L553 K557	L553-S555 PolarHBondContact O-N 3.42Å; S555-K557 PolarHBondContact O-N 3.27Å
556	Q	29.7	Very low	38.6	Very low	195 Å²	195	119.6 Å²	119.6	91%	0.911	62%	0.622	S	S	*	*			trans	-62.3	79.1	162.5	-77.8	-161.2	-30.7	0	0	106.5	P554	P554-Q556 PolarHBondContact O-N 3.07Å
557	K	25.5	Very low	38	Very low	161 Å²	161	124.3 Å²	124.3	70%	0.7	64%	0.637	S	S	*	*			trans	-93.2	122.8	158	-80.4	-174.4	173.8	-175	0	103.9	S555	S555-K557 PolarHBondContact O-N 3.27Å
558	H	28.5	Very low	37.5	Very low	257 Å²	257	122.1 Å²	122.1	100%	1.19	64%	0.636	S	S	*	*			trans	96.1	0	178.8	-53.3	-63.5	0	0	0	115.1

Retrieved 558 of 558 residues in 245 ms (Link to these results)

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