A0A077ZE87_TRITR Loading...

Orn

AlphaFold DB , UniProt , Accession A0A077ZE87, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 756 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M82.8Confident86Confident155 Ų15540.8 Ų40.876%0.76419%0.191SC*.  0149.90-160.1168.5-74.300108.7N33 T35 R136M1-N33 WeakPolarHBondContact CG-O 3.25Å; M1-T35 PolarHBondContact SD-OG1 3.3Å; M1-R136 PolarHBondContact O-NH2 3.17Å
2M92.5Very high84.5Confident36 Ų3638.8 Ų38.818%0.17718%0.182CC..EExtended strand (participates in β ladder)trans-76.6148.2171.6-80.7178.6-92.300110.5V34 T35 D56 V129 M132 R136M2-V34 HydrophobicContact CB-CG1 4.22Å; M2-V34 HydrophobicContact CB-CG2 4.2Å; M2-V34 CarbonylContact O-C 3.5Å; M2-V34 WeakPolarHBondContact O-CA 3.23Å; M2-T35 PolarHBondContact O-N 2.93Å; M2-D56 VanDerWaalsContact CA-OD2 3.25Å; M2-D56 WeakPolarHBondContact CA-OD2 3.34Å; M2-V129 HydrophobicContact CE-CG1 4.21Å; M2-M132 HydrophobicContact CB-SD 4.01Å; M2-M132 HydrophobicContact CG-CB 4.41Å; M2-M132 HydrophobicContact CG-SD 4.43Å; M2-M132 HydrophobicContact SD-CB 3.54Å; M2-M132 VanDerWaalsContact SD-CB 3.54Å; M2-M132 HydrophobicContact SD-CG 4.47Å; M2-M132 HydrophobicContact SD-SD 4.26Å; M2-R136 VanDerWaalsContact CA-NH2 3.35Å
3K95.9Very high82.9Confident68 Ų6845.6 Ų45.630%0.29621%0.214SC..EExtended strand (participates in β ladder)trans-126.4136.2179.9-73.6177.6173.4-171.60110.7T35 E53 A54 D56 C57K3-T35 WeakPolarHBondContact CA-O 3.27Å; K3-T35 HydrophobicContact CG-CG2 4.46Å; K3-E53 IonicContact NZ-OE1 3.83Å; K3-E53 PolarHBondContact NZ-OE1 3.3Å; K3-A54 VanDerWaalsContact CD-O 3.23Å; K3-A54 WeakPolarHBondContact CD-O 3.26Å; K3-D56 PolarHBondContact N-OD2 3.05Å; K3-D56 WeakPolarHBondContact O-CA 3.5Å; K3-D56 WeakPolarHBondContact O-CB 3.45Å; K3-D56 PolarHBondContact O-N 3.24Å; K3-C57 PolarHBondContact O-N 3.26Å
4V96.7Very high81.4Confident0 Ų050.3 Ų50.30%024%0.236CC..EExtended strand (participates in β ladder)trans-128.8133.4174.661.70000109.6I6 L29 V34 T35 V36 I37 C57 M59V4-I6 HydrophobicContact CG2-CG1 4.42Å; V4-L29 HydrophobicContact CG1-CD1 3.96Å; V4-V34 HydrophobicContact CB-CG1 4.08Å; V4-V34 HydrophobicContact CG1-CG1 3.62Å; V4-T35 PolarHBondContact N-O 2.93Å; V4-V36 HydrophobicContact CG1-CB 4.25Å; V4-V36 HydrophobicContact CG1-CG1 4.29Å; V4-V36 HydrophobicContact CG1-CG2 3.84Å; V4-I37 PolarHBondContact O-N 3.24Å; V4-C57 WeakPolarHBondContact CA-O 3.37Å; V4-C57 HydrophobicContact CB-CB 4.4Å; V4-C57 HydrophobicContact CG2-CB 3.94Å; V4-M59 HydrophobicContact CG2-CE 4.07Å; V4-M59 HydrophobicContact CG2-CG 3.76Å; V4-M59 HydrophobicContact CG2-SD 4Å
5L96.4Very high80.5Confident0 Ų057.5 Ų57.50%028%0.277CS..EExtended strand (participates in β ladder)trans-97.7120.9171.3174.759.7000108.7V7 I37 I48 L49 I55 C57 L58 M59L5-V7 HydrophobicContact CD1-CG2 4.18Å; L5-V7 HydrophobicContact CD2-CG2 3.99Å; L5-V7 HydrophobicContact CG-CG2 3.77Å; L5-I37 CarbonylContact C-O 3.4Å; L5-I37 WeakPolarHBondContact CA-O 3.37Å; L5-I37 HydrophobicContact CD1-CB 4.13Å; L5-I37 HydrophobicContact CD1-CG2 3.87Å; L5-I48 HydrophobicContact CD1-CD1 3.86Å; L5-I48 HydrophobicContact CD1-CG2 4.32Å; L5-I48 HydrophobicContact CD2-CB 4.47Å; L5-I48 HydrophobicContact CD2-CG2 4.11Å; L5-L49 HydrophobicContact CD2-CD2 3.82Å; L5-L49 HydrophobicContact CD2-CG 3.99Å; L5-I55 HydrophobicContact CB-CD1 3.85Å; L5-I55 HydrophobicContact CB-CG2 4.13Å; L5-I55 HydrophobicContact CD2-CD1 4.32Å; L5-C57 PolarHBondContact N-O 2.86Å; L5-L58 HydrophobicContact CB-CD1 4.23Å; L5-L58 HydrophobicContact CD2-CD1 3.98Å; L5-L58 HydrophobicContact CG-CD1 4Å; L5-M59 PolarHBondContact O-N 3.16Å
6I94.6Very high80.1Confident1 Ų156.8 Ų56.81%0.00528%0.277CS..EExtended strand (participates in β ladder)trans-105116172.1-54.9-178000107.7V4 E8 V22 A26 L29 V36 I37 K38 S39 M59 L92V4-I6 HydrophobicContact CG2-CG1 4.42Å; I6-E8 HydrophobicContact CG2-CG 4.38Å; I6-V22 HydrophobicContact CG2-CG1 3.72Å; I6-A26 HydrophobicContact CD1-CB 4.21Å; I6-L29 HydrophobicContact CD1-CD1 4.13Å; I6-V36 HydrophobicContact CD1-CG1 3.62Å; I6-V36 HydrophobicContact CG1-CG1 4.02Å; I6-I37 PolarHBondContact N-O 2.74Å; I6-K38 WeakPolarHBondContact O-CA 3.49Å; I6-S39 PolarHBondContact O-N 2.93Å; I6-M59 CarbonylContact C-O 3.55Å; I6-M59 WeakPolarHBondContact CA-O 3.24Å; I6-M59 HydrophobicContact CG1-CB 4.25Å; I6-M59 HydrophobicContact CG1-SD 4.34Å; I6-L92 HydrophobicContact CG2-CD1 4.32Å
7V91.5Very high79.9Confident0 Ų064.4 Ų64.40%030%0.302CS..EExtended strand (participates in β ladder)trans-105.1109.7177.1-1750000109.5L5 S41 F42 L58 M59 F60 S61 L76L5-V7 HydrophobicContact CD1-CG2 4.18Å; L5-V7 HydrophobicContact CD2-CG2 3.99Å; L5-V7 HydrophobicContact CG-CG2 3.77Å; V7-S41 WeakPolarHBondContact CG1-O 3.48Å; V7-F42 HydrophobicContact CG1-CD1 3.78Å; V7-F42 HydrophobicContact CG1-CE1 4.02Å; V7-F42 HydrophobicContact CG1-CG 4.35Å; V7-L58 HydrophobicContact CG2-CD1 3.88Å; V7-M59 PolarHBondContact N-O 2.86Å; V7-F60 HydrophobicContact CB-CB 4.21Å; V7-F60 VanDerWaalsContact O-CA 3.22Å; V7-F60 WeakPolarHBondContact O-CA 3.33Å; V7-S61 PolarHBondContact O-N 2.89Å; V7-L76 HydrophobicContact CB-CD2 4.18Å; V7-L76 HydrophobicContact CG1-CD2 4.18Å; V7-L76 HydrophobicContact CG2-CD2 3.93Å
8E85.6Confident79.8Confident8 Ų863.2 Ų63.24%0.03730%0.3CS..EExtended strand (participates in β ladder)trans-90.8140.4173.7-63.3179.6-121.700109.7I6 V22 S39 T40 S41I6-E8 HydrophobicContact CG2-CG 4.38Å; E8-V22 HydrophobicContact CG-CG1 4.15Å; E8-S39 PolarHBondContact N-O 3.05Å; E8-T40 CarbonylContact O-C 2.92Å; E8-S41 WeakPolarHBondContact O-CA 3.49Å; E8-S41 PolarHBondContact O-N 3.34Å
9S77.6Confident79.8Confident1 Ų159.9 Ų59.91%0.00728%0.284CS..  trans-61.9141.2168.7176.30000110F11 L12 S61 E69S9-F11 PolarHBondContact O-N 3.14Å; S9-F11 VanDerWaalsContact OG-CD2 3.24Å; S9-F11 WeakPolarHBondContact OG-CD2 3.36Å; S9-F11 PolarHBondContact OG-N 2.97Å; S9-L12 WeakPolarHBondContact O-CB 3.46Å; S9-L12 PolarHBondContact O-N 3.25Å; S9-S61 WeakPolarHBondContact CB-O 3.4Å; S9-S61 PolarHBondContact N-O 3.47Å; S9-E69 WeakPolarHBondContact CB-OE1 3.31Å; S9-E69 PolarHBondContact OG-OE1 3.19Å
10E69.9Low80Confident99 Ų9960.5 Ų60.546%0.46329%0.289SS..THydrogen-bonded Turntrans-59-17.9173.260.7-156.7-143.300113.3T40E10-T40 WeakPolarHBondContact CA-O 3.42Å
11F63.1Low80.4Confident81 Ų8157.8 Ų57.836%0.35528%0.277SS..THydrogen-bonded Turntrans-84.1-9.2175.2-52.8-66000113.3S9 H13 Q63 H66 E69S9-F11 PolarHBondContact O-N 3.14Å; S9-F11 VanDerWaalsContact OG-CD2 3.24Å; S9-F11 WeakPolarHBondContact OG-CD2 3.36Å; S9-F11 PolarHBondContact OG-N 2.97Å; F11-H13 PolarHBondContact O-N 2.67Å; F11-Q63 PolarHBondContact O-NE2 3.47Å; F11-H66 AromaticContact CD2-CD2 3.9Å; F11-H66 AromaticContact CE2-CD2 3.84Å; F11-E69 HydrophobicContact CD2-CG 4.33Å; F11-E69 WeakPolarHBondContact CD2-OE1 3.43Å; F11-E69 HydrophobicContact CE2-CG 4.27Å
12L67.7Low80.7Confident16 Ų1650.4 Ų50.48%0.08424%0.24CC..  trans-88.6101.3175.7-103.7141.8000110.3S9 V18S9-L12 WeakPolarHBondContact O-CB 3.46Å; S9-L12 PolarHBondContact O-N 3.25Å; L12-V18 HydrophobicContact CD2-CB 3.76Å; L12-V18 HydrophobicContact CD2-CG1 3.56Å
13H63.2Low80.5Confident128 Ų12851.3 Ų51.359%0.59324%0.244SC*.  trans-75135.9173.3-60.7-54.2000111.2F11 D15 T16F11-H13 PolarHBondContact O-N 2.67Å; H13-D15 PolarHBondContact O-N 3.44Å; H13-D15 VanDerWaalsContact O-N 3.16Å; H13-T16 HydrophobicContact CB-CG2 3.92Å; H13-T16 VanDerWaalsContact O-CB 3.27Å; H13-T16 WeakPolarHBondContact O-CB 3.33Å; H13-T16 VanDerWaalsContact O-CG2 3.25Å; H13-T16 WeakPolarHBondContact O-CG2 3.33Å; H13-T16 PolarHBondContact O-N 3.01Å; H13-T16 PolarHBondContact O-OG1 3.31Å
14Q62.5Low80.3Confident111 Ų11153.1 Ų53.152%0.51925%0.249SC..THydrogen-bonded Turntrans-57.9-28.3175.9-69.9-174.1-19.300112.9T16 N20Q14-T16 PolarHBondContact O-N 3.39Å; Q14-T16 VanDerWaalsContact O-N 3.17Å; Q14-N20 PolarHBondContact O-ND2 2.99Å
15D67.8Low80.2Confident159 Ų15953.2 Ų53.285%0.8525%0.249SC*.THydrogen-bonded Turntrans-73.2-0.2176.3-64.4-27.1000113.6H13H13-D15 PolarHBondContact O-N 3.44Å; H13-D15 VanDerWaalsContact O-N 3.16Å
16T73.7Confident80Confident45 Ų4553.3 Ų53.328%0.27625%0.251SS..SBendtrans-84.4157.6175.468.20000111.6H13 Q14 V18 G19 N20H13-T16 HydrophobicContact CB-CG2 3.92Å; H13-T16 VanDerWaalsContact O-CB 3.27Å; H13-T16 WeakPolarHBondContact O-CB 3.33Å; H13-T16 VanDerWaalsContact O-CG2 3.25Å; H13-T16 WeakPolarHBondContact O-CG2 3.33Å; H13-T16 PolarHBondContact O-N 3.01Å; H13-T16 PolarHBondContact O-OG1 3.31Å; Q14-T16 PolarHBondContact O-N 3.39Å; Q14-T16 VanDerWaalsContact O-N 3.17Å; T16-V18 PolarHBondContact O-N 3.17Å; T16-G19 PolarHBondContact O-N 3.21Å; T16-G19 PolarHBondContact OG1-N 3.09Å; T16-N20 PolarHBondContact O-N 3.34Å; T16-N20 PolarHBondContact O-ND2 3.34Å
17W76.2Confident80Confident187 Ų18757.7 Ų57.771%0.70827%0.274SS*.Hα-helixtrans-61.7-32.3174.8-170.4-98.8000112.4A21 L117W17-A21 PolarHBondContact O-N 2.89Å; W17-A21 VanDerWaalsContact O-N 3.09Å; W17-L117 VanDerWaalsContact CD1-CD2 3.49Å
18V78.3Confident80.2Confident43 Ų4358 Ų5826%0.26128%0.277SS..Hα-helixtrans-70.3-48.1177-172.80000110.6L12 T16 N20 A21 V22 I116 L117L12-V18 HydrophobicContact CD2-CB 3.76Å; L12-V18 HydrophobicContact CD2-CG1 3.56Å; T16-V18 PolarHBondContact O-N 3.17Å; V18-N20 VanDerWaalsContact C-N 3.33Å; V18-N20 PolarHBondContact O-N 3.32Å; V18-A21 WeakPolarHBondContact O-CA 3.39Å; V18-A21 VanDerWaalsContact O-CB 3.29Å; V18-A21 WeakPolarHBondContact O-CB 3.24Å; V18-A21 PolarHBondContact O-N 3.49Å; V18-V22 PolarHBondContact O-N 3.3Å; V18-I116 HydrophobicContact CG1-CD1 3.38Å; V18-I116 HydrophobicContact CG1-CG1 4.49Å; V18-L117 HydrophobicContact CG2-CD1 4.39Å
19G80.1Confident80.7Confident0 Ų057.7 Ų57.70%028%0.275CS..Hα-helixtrans-57.2-44.817400000112.2T16 A21 V22 E23T16-G19 PolarHBondContact O-N 3.21Å; T16-G19 PolarHBondContact OG1-N 3.09Å; G19-A21 PolarHBondContact O-N 3.12Å; G19-V22 PolarHBondContact O-N 2.98Å; G19-V22 VanDerWaalsContact O-N 3.14Å; G19-E23 PolarHBondContact O-N 2.99Å
20N84.2Confident81.6Confident71 Ų7160.5 Ų60.538%0.3830%0.295SS..Hα-helixtrans-62.1-28.1173-76.9-68.5000113.7Q14 T16 V18 R24Q14-N20 PolarHBondContact O-ND2 2.99Å; T16-N20 PolarHBondContact O-N 3.34Å; T16-N20 PolarHBondContact O-ND2 3.34Å; V18-N20 VanDerWaalsContact C-N 3.33Å; V18-N20 PolarHBondContact O-N 3.32Å; N20-R24 WeakPolarHBondContact O-CG 3.37Å; N20-R24 PolarHBondContact O-N 3.48Å; N20-R24 VanDerWaalsContact O-N 3.17Å; N20-R24 PolarHBondContact O-NH1 3.36Å
21A87.9Confident82.8Confident4 Ų463 Ų633%0.03331%0.307CS..Hα-helixtrans-72.9-38.7174.500000111.9W17 V18 G19 R24 L25 I116 L117W17-A21 PolarHBondContact O-N 2.89Å; W17-A21 VanDerWaalsContact O-N 3.09Å; V18-A21 WeakPolarHBondContact O-CA 3.39Å; V18-A21 VanDerWaalsContact O-CB 3.29Å; V18-A21 WeakPolarHBondContact O-CB 3.24Å; V18-A21 PolarHBondContact O-N 3.49Å; G19-A21 PolarHBondContact O-N 3.12Å; A21-R24 PolarHBondContact O-N 3.33Å; A21-L25 PolarHBondContact O-N 2.64Å; A21-I116 HydrophobicContact CB-CB 4.28Å; A21-I116 HydrophobicContact CB-CD1 4.49Å; A21-L117 HydrophobicContact CB-CD2 4.15Å
22V88.6Confident84.1Confident0 Ų063.3 Ų63.30%031%0.309CS..Hα-helixtrans-63.6-41.2172.9178.40000110.9I6 E8 V18 G19 L25 A26 L92 I116I6-V22 HydrophobicContact CG2-CG1 3.72Å; E8-V22 HydrophobicContact CG-CG1 4.15Å; V18-V22 PolarHBondContact O-N 3.3Å; G19-V22 PolarHBondContact O-N 2.98Å; G19-V22 VanDerWaalsContact O-N 3.14Å; V22-L25 WeakPolarHBondContact O-CB 3.29Å; V22-L25 PolarHBondContact O-N 3.36Å; V22-A26 PolarHBondContact O-N 3.12Å; V22-L92 HydrophobicContact CG2-CD1 4.38Å; V22-I116 HydrophobicContact CG2-CD1 4.15Å
23E89.3Confident85.3Confident55 Ų5568.4 Ų68.426%0.25734%0.337SS..Hα-helixtrans-59.2-48.3173.7-74.2-58.5139.400112.3G19 L25 A26 D27 K38G19-E23 PolarHBondContact O-N 2.99Å; E23-L25 VanDerWaalsContact C-N 3.26Å; E23-L25 PolarHBondContact O-N 3.01Å; E23-A26 WeakPolarHBondContact O-CB 3.43Å; E23-A26 PolarHBondContact O-N 3.03Å; E23-A26 VanDerWaalsContact O-N 3.16Å; E23-D27 PolarHBondContact O-N 3.39Å; E23-K38 IonicContact OE1-NZ 2.65Å; E23-K38 PolarHBondContact OE1-NZ 3.42Å; E23-K38 IonicContact OE2-NZ 2.74Å; E23-K38 PolarHBondContact OE2-NZ 3.43Å
24R91.8Very high86.9Confident107 Ų10762.5 Ų62.540%0.40431%0.31SS..Hα-helixtrans-60.1-36.3175.3-72.7-173.6-60.6-89.54.3112.5N20 A21 A28 A121N20-R24 WeakPolarHBondContact O-CG 3.37Å; N20-R24 PolarHBondContact O-N 3.48Å; N20-R24 VanDerWaalsContact O-N 3.17Å; N20-R24 PolarHBondContact O-NH1 3.36Å; A21-R24 PolarHBondContact O-N 3.33Å; R24-A28 WeakPolarHBondContact O-CB 3.28Å; R24-A28 PolarHBondContact O-N 2.94Å; R24-A121 HydrophobicContact CB-CB 4.05Å
25L93.7Very high88.5Confident1 Ų159.7 Ų59.71%0.00530%0.3CS..Hα-helixtrans-66.7-44.2175.4176.358.2000111.5A21 V22 E23 D27 A28 L29 M59 L92 I124 A125A21-L25 PolarHBondContact O-N 2.64Å; V22-L25 WeakPolarHBondContact O-CB 3.29Å; V22-L25 PolarHBondContact O-N 3.36Å; E23-L25 VanDerWaalsContact C-N 3.26Å; E23-L25 PolarHBondContact O-N 3.01Å; L25-D27 VanDerWaalsContact C-N 3.32Å; L25-D27 PolarHBondContact O-N 3Å; L25-A28 PolarHBondContact O-N 2.82Å; L25-L29 HydrophobicContact CD1-CD1 4.1Å; L25-L29 HydrophobicContact CD1-CG 4.28Å; L25-L29 HydrophobicContact CG-CD1 3.95Å; L25-L29 WeakPolarHBondContact O-CG 3.41Å; L25-L29 PolarHBondContact O-N 3.24Å; L25-M59 HydrophobicContact CD2-SD 3.94Å; L25-L92 HydrophobicContact CD2-CD1 4.04Å; L25-L92 HydrophobicContact CD2-CD2 3.97Å; L25-I124 HydrophobicContact CD1-CB 3.83Å; L25-I124 HydrophobicContact CD1-CG2 3.63Å; L25-I124 HydrophobicContact CD2-CG2 3.9Å; L25-I124 HydrophobicContact CG-CG2 4.45Å; L25-A125 HydrophobicContact CD1-CB 4.15Å
26A93.6Very high89.9Confident3 Ų353.7 Ų53.73%0.02527%0.269CS..Hα-helixtrans-60.5-40.7175.700000112.4I6 V22 E23 L29 S30 V36I6-A26 HydrophobicContact CD1-CB 4.21Å; V22-A26 PolarHBondContact O-N 3.12Å; E23-A26 WeakPolarHBondContact O-CB 3.43Å; E23-A26 PolarHBondContact O-N 3.03Å; E23-A26 VanDerWaalsContact O-N 3.16Å; A26-L29 PolarHBondContact O-N 2.94Å; A26-S30 WeakPolarHBondContact O-CB 3.48Å; A26-S30 PolarHBondContact O-N 3.01Å; A26-S30 PolarHBondContact O-OG 3.24Å; A26-V36 HydrophobicContact CB-CG1 4.03Å; A26-V36 HydrophobicContact CB-CG2 4.48Å
27D94.8Very high90.9Very high92 Ų9253.4 Ų53.449%0.49227%0.265SS..Hα-helixtrans-63.5-44.7173.7-75.2-18.8000111.6E23 L25 L29 S30 Q31E23-D27 PolarHBondContact O-N 3.39Å; L25-D27 VanDerWaalsContact C-N 3.32Å; L25-D27 PolarHBondContact O-N 3Å; D27-L29 PolarHBondContact O-N 2.89Å; D27-S30 PolarHBondContact O-N 2.96Å; D27-Q31 VanDerWaalsContact O-CG 3.32Å; D27-Q31 WeakPolarHBondContact O-CG 3.27Å; D27-Q31 PolarHBondContact O-N 2.94Å
28A95.5Very high91.6Very high8 Ų847.9 Ų47.97%0.06625%0.246CC..Hα-helixtrans-62.1-40.9177.300000112.1R24 L25 Q31 Q32 A121 A125R24-A28 WeakPolarHBondContact O-CB 3.28Å; R24-A28 PolarHBondContact O-N 2.94Å; L25-A28 PolarHBondContact O-N 2.82Å; A28-Q31 PolarHBondContact O-N 2.65Å; A28-Q32 WeakPolarHBondContact O-CG 3.47Å; A28-Q32 PolarHBondContact O-N 2.65Å; A28-A121 HydrophobicContact CB-CB 4.16Å; A28-A125 HydrophobicContact CB-CB 3.83Å
29L95.9Very high92.3Very high0 Ų045.8 Ų45.80%023%0.234CC..Hα-helixtrans-63-43.2174.2-74.8159.6000111.6V4 I6 L25 A26 D27 Q31 Q32 V34 V36 M59 A125 A128 M132V4-L29 HydrophobicContact CG1-CD1 3.96Å; I6-L29 HydrophobicContact CD1-CD1 4.13Å; L25-L29 HydrophobicContact CD1-CD1 4.1Å; L25-L29 HydrophobicContact CD1-CG 4.28Å; L25-L29 HydrophobicContact CG-CD1 3.95Å; L25-L29 WeakPolarHBondContact O-CG 3.41Å; L25-L29 PolarHBondContact O-N 3.24Å; A26-L29 PolarHBondContact O-N 2.94Å; D27-L29 PolarHBondContact O-N 2.89Å; L29-Q31 VanDerWaalsContact C-N 3.34Å; L29-Q31 PolarHBondContact O-N 3.19Å; L29-Q32 CarbonylContact O-C 3.37Å; L29-Q32 WeakPolarHBondContact O-CA 2.87Å; L29-Q32 WeakPolarHBondContact O-CB 3.3Å; L29-Q32 PolarHBondContact O-N 3.39Å; L29-V34 HydrophobicContact CB-CB 4.26Å; L29-V34 HydrophobicContact CD2-CG2 4.41Å; L29-V34 VanDerWaalsContact O-CB 3.31Å; L29-V34 WeakPolarHBondContact O-CB 3.34Å; L29-V34 PolarHBondContact O-N 3.39Å; L29-V34 VanDerWaalsContact O-N 3.1Å; L29-V36 HydrophobicContact CB-CG2 3.71Å; L29-V36 HydrophobicContact CD1-CG2 4.38Å; L29-M59 HydrophobicContact CD1-CE 4.21Å; L29-M59 HydrophobicContact CD1-SD 4.1Å; L29-M59 HydrophobicContact CD2-CE 4.47Å; L29-A125 HydrophobicContact CD2-CB 3.99Å; L29-A125 HydrophobicContact CG-CB 3.99Å; L29-A128 HydrophobicContact CD2-CB 4.12Å; L29-M132 HydrophobicContact CD2-CE 4.16Å
30S95.2Very high92.5Very high61 Ų6150.3 Ų50.343%0.42726%0.261SS..Hα-helixtrans-63.5-39178.2-600000112.1A26 D27 Q32 N33 V34A26-S30 WeakPolarHBondContact O-CB 3.48Å; A26-S30 PolarHBondContact O-N 3.01Å; A26-S30 PolarHBondContact O-OG 3.24Å; D27-S30 PolarHBondContact O-N 2.96Å; S30-Q32 PolarHBondContact O-N 3.47Å; S30-N33 PolarHBondContact O-N 3.4Å; S30-V34 WeakPolarHBondContact CA-O 3.48Å
31Q94.8Very high92.7Very high151 Ų15147.9 Ų47.971%0.70625%0.25SS*.Hα-helixtrans-62.7-24.4173.7-71.6172.719.200113D27 A28 L29 N33D27-Q31 VanDerWaalsContact O-CG 3.32Å; D27-Q31 WeakPolarHBondContact O-CG 3.27Å; D27-Q31 PolarHBondContact O-N 2.94Å; A28-Q31 PolarHBondContact O-N 2.65Å; L29-Q31 VanDerWaalsContact C-N 3.34Å; L29-Q31 PolarHBondContact O-N 3.19Å; Q31-N33 VanDerWaalsContact C-N 3.3Å
32Q92.4Very high92.8Very high88 Ų8848 Ų4841%0.41125%0.25SS..THydrogen-bonded Turntrans-89.815.8175.1-61.1-70.4-17.800113.1A28 L29 S30 V34 V129A28-Q32 WeakPolarHBondContact O-CG 3.47Å; A28-Q32 PolarHBondContact O-N 2.65Å; L29-Q32 CarbonylContact O-C 3.37Å; L29-Q32 WeakPolarHBondContact O-CA 2.87Å; L29-Q32 WeakPolarHBondContact O-CB 3.3Å; L29-Q32 PolarHBondContact O-N 3.39Å; S30-Q32 PolarHBondContact O-N 3.47Å; Q32-V34 VanDerWaalsContact C-N 3.28Å; Q32-V34 HydrophobicContact CB-CG2 4.39Å; Q32-V34 PolarHBondContact O-N 3.43Å; Q32-V129 HydrophobicContact CB-CG2 4.12Å
33N92.6Very high92.8Very high123 Ų12353.4 Ų53.466%0.65828%0.279SS*.THydrogen-bonded Turntrans58.634.7-175.2-59.9-59.9000113.9M1 S30 Q31M1-N33 WeakPolarHBondContact CG-O 3.25Å; S30-N33 PolarHBondContact O-N 3.4Å; Q31-N33 VanDerWaalsContact C-N 3.3Å
34V96Very high92.9Very high4 Ų454 Ų542%0.02428%0.284CS..EExtended strand (participates in β ladder)trans-97.9128.9169.2-174.30000108.6M2 V4 L29 S30 Q32 V36 V129 M132M2-V34 HydrophobicContact CB-CG1 4.22Å; M2-V34 HydrophobicContact CB-CG2 4.2Å; M2-V34 CarbonylContact O-C 3.5Å; M2-V34 WeakPolarHBondContact O-CA 3.23Å; V4-V34 HydrophobicContact CB-CG1 4.08Å; V4-V34 HydrophobicContact CG1-CG1 3.62Å; L29-V34 HydrophobicContact CB-CB 4.26Å; L29-V34 HydrophobicContact CD2-CG2 4.41Å; L29-V34 VanDerWaalsContact O-CB 3.31Å; L29-V34 WeakPolarHBondContact O-CB 3.34Å; L29-V34 PolarHBondContact O-N 3.39Å; L29-V34 VanDerWaalsContact O-N 3.1Å; S30-V34 WeakPolarHBondContact CA-O 3.48Å; Q32-V34 VanDerWaalsContact C-N 3.28Å; Q32-V34 HydrophobicContact CB-CG2 4.39Å; Q32-V34 PolarHBondContact O-N 3.43Å; V34-V36 PolarHBondContact O-N 3.46Å; V34-V129 HydrophobicContact CG2-CG2 3.84Å; V34-M132 HydrophobicContact CG1-CE 3.99Å; V34-M132 HydrophobicContact CG1-SD 4.14Å; V34-M132 HydrophobicContact CG2-CE 3.93Å
35T96.5Very high93Very high52 Ų5248.9 Ų48.932%0.31926%0.264SS..EExtended strand (participates in β ladder)trans-74.8118.7169.7-56.10000109.1M1 M2 K3 V4M1-T35 PolarHBondContact SD-OG1 3.3Å; M2-T35 PolarHBondContact O-N 2.93Å; K3-T35 WeakPolarHBondContact CA-O 3.27Å; K3-T35 HydrophobicContact CG-CG2 4.46Å; V4-T35 PolarHBondContact N-O 2.93Å
36V96Very high92.9Very high33 Ų3352.5 Ų52.520%0.228%0.28CS..EExtended strand (participates in β ladder)trans-96122.1177.6-175.60000109.8V4 I6 A26 L29 V34 K38V4-V36 HydrophobicContact CG1-CB 4.25Å; V4-V36 HydrophobicContact CG1-CG1 4.29Å; V4-V36 HydrophobicContact CG1-CG2 3.84Å; I6-V36 HydrophobicContact CD1-CG1 3.62Å; I6-V36 HydrophobicContact CG1-CG1 4.02Å; A26-V36 HydrophobicContact CB-CG1 4.03Å; A26-V36 HydrophobicContact CB-CG2 4.48Å; L29-V36 HydrophobicContact CB-CG2 3.71Å; L29-V36 HydrophobicContact CD1-CG2 4.38Å; V34-V36 PolarHBondContact O-N 3.46Å; V36-K38 HydrophobicContact CG1-CG 3.95Å
37I95Very high92.9Very high38 Ų3854.8 Ų54.820%0.19530%0.299CS..EExtended strand (participates in β ladder)trans-102.5125.3169.5-56.2164000106.5V4 L5 I6 I48 E53 I55V4-I37 PolarHBondContact O-N 3.24Å; L5-I37 CarbonylContact C-O 3.4Å; L5-I37 WeakPolarHBondContact CA-O 3.37Å; L5-I37 HydrophobicContact CD1-CB 4.13Å; L5-I37 HydrophobicContact CD1-CG2 3.87Å; I6-I37 PolarHBondContact N-O 2.74Å; I37-I48 HydrophobicContact CG2-CD1 4.02Å; I37-E53 HydrophobicContact CD1-CG 3.66Å; I37-I55 HydrophobicContact CD1-CG2 4.39Å
38K92.4Very high92.8Very high71 Ų7151.8 Ų51.831%0.30928%0.283SS..EExtended strand (participates in β ladder)trans-110.2136.2179.4-64-170.6-179.9178.90110.5I6 E23 V36I6-K38 WeakPolarHBondContact O-CA 3.49Å; E23-K38 IonicContact OE1-NZ 2.65Å; E23-K38 PolarHBondContact OE1-NZ 3.42Å; E23-K38 IonicContact OE2-NZ 2.74Å; E23-K38 PolarHBondContact OE2-NZ 3.43Å; V36-K38 HydrophobicContact CG1-CG 3.95Å
39S91.6Very high92.7Very high0 Ų051.7 Ų51.70%028%0.281CS..EExtended strand (participates in β ladder)trans-115.9138.4168.6176.30000109.6I6 E8 S41 D44 G45I6-S39 PolarHBondContact O-N 2.93Å; E8-S39 PolarHBondContact N-O 3.05Å; S39-S41 PolarHBondContact OG-N 3.06Å; S39-S41 PolarHBondContact OG-O 3.27Å; S39-D44 VanDerWaalsContact OG-CB 3.24Å; S39-D44 WeakPolarHBondContact OG-CB 3.37Å; S39-D44 PolarHBondContact OG-OD2 3.35Å; S39-G45 PolarHBondContact OG-N 3.19Å
40T85.8Confident92.3Very high94 Ų9452.6 Ų52.658%0.57729%0.288SS*.SBendtrans-94.7-0.3-179.656.10000113.8E8 E10E8-T40 CarbonylContact O-C 2.92Å; E10-T40 WeakPolarHBondContact CA-O 3.42Å
41S87.9Confident91.9Very high21 Ų2153.6 Ų53.615%0.14729%0.294CS..SBendtrans-152.5165175.163.30000111.1V7 E8 S39 D43 D44 G45V7-S41 WeakPolarHBondContact CG1-O 3.48Å; E8-S41 WeakPolarHBondContact O-CA 3.49Å; E8-S41 PolarHBondContact O-N 3.34Å; S39-S41 PolarHBondContact OG-N 3.06Å; S39-S41 PolarHBondContact OG-O 3.27Å; S41-D43 VanDerWaalsContact C-N 3.31Å; S41-D44 WeakPolarHBondContact OG-CB 3.39Å; S41-D44 PolarHBondContact OG-N 3.23Å; S41-D44 VanDerWaalsContact OG-N 3.12Å; S41-G45 PolarHBondContact O-N 2.89Å; S41-G45 VanDerWaalsContact O-N 3.13Å
42F89Confident91.4Very high7 Ų748.9 Ų48.93%0.03127%0.274CS..Hα-helixtrans-65.8-35.1172.1-77.4-72000112.5V7 G45 F46 F60 Y62 N72 V73 L76V7-F42 HydrophobicContact CG1-CD1 3.78Å; V7-F42 HydrophobicContact CG1-CE1 4.02Å; V7-F42 HydrophobicContact CG1-CG 4.35Å; F42-G45 PolarHBondContact O-N 3.29Å; F42-F46 WeakPolarHBondContact O-CB 3.42Å; F42-F46 PolarHBondContact O-N 3.3Å; F42-F60 HydrophobicContact CE1-CB 4.39Å; F42-F60 HydrophobicContact CE1-CD2 4.39Å; F42-F60 HydrophobicContact CZ-CD2 4.48Å; F42-Y62 HydrophobicContact CZ-CG 4.38Å; F42-N72 HydrophobicContact CB-CB 3.9Å; F42-N72 HydrophobicContact CD1-CB 4.49Å; F42-N72 HydrophobicContact CD2-CB 4.3Å; F42-N72 HydrophobicContact CG-CB 3.97Å; F42-V73 HydrophobicContact CD1-CG2 4.36Å; F42-V73 HydrophobicContact CE1-CG2 3.49Å; F42-V73 VanDerWaalsContact CE1-CG2 3.49Å; F42-V73 HydrophobicContact CE2-CG2 4.4Å; F42-V73 HydrophobicContact CZ-CG2 3.51Å; F42-L76 HydrophobicContact CD1-CD2 4.04Å; F42-L76 HydrophobicContact CE1-CD2 4.23Å
43D89.7Confident91.3Very high113 Ų11347.3 Ų47.360%0.60427%0.267SS*.Hα-helixtrans-65.2-43.2178.6-75.7-6.6000112.3S41 G45 F46 A47S41-D43 VanDerWaalsContact C-N 3.31Å; D43-G45 VanDerWaalsContact C-N 3.34Å; D43-F46 WeakPolarHBondContact O-CB 3.22Å; D43-F46 PolarHBondContact O-N 3.48Å; D43-A47 PolarHBondContact O-N 3.14Å
44D91.6Very high91.2Very high67 Ų6744.5 Ų44.536%0.35826%0.261SS..Hα-helixtrans-66.8-37.8175.4-178.741.4000111S39 S41 F46 A47 I48S39-D44 VanDerWaalsContact OG-CB 3.24Å; S39-D44 WeakPolarHBondContact OG-CB 3.37Å; S39-D44 PolarHBondContact OG-OD2 3.35Å; S41-D44 WeakPolarHBondContact OG-CB 3.39Å; S41-D44 PolarHBondContact OG-N 3.23Å; S41-D44 VanDerWaalsContact OG-N 3.12Å; D44-F46 VanDerWaalsContact C-N 3.33Å; D44-F46 PolarHBondContact O-N 3.13Å; D44-A47 WeakPolarHBondContact O-CB 3.47Å; D44-A47 PolarHBondContact O-N 2.64Å; D44-I48 WeakPolarHBondContact O-CG1 3.33Å; D44-I48 PolarHBondContact O-N 2.94Å
45G92.7Very high91.1Very high0 Ų044.4 Ų44.40%026%0.26CS..Hα-helixtrans-61.7-43.1172.900000111.6S39 S41 F42 D43 I48 L49 L76S39-G45 PolarHBondContact OG-N 3.19Å; S41-G45 PolarHBondContact O-N 2.89Å; S41-G45 VanDerWaalsContact O-N 3.13Å; F42-G45 PolarHBondContact O-N 3.29Å; D43-G45 VanDerWaalsContact C-N 3.34Å; G45-I48 PolarHBondContact O-N 2.83Å; G45-L49 WeakPolarHBondContact O-CG 3.47Å; G45-L49 PolarHBondContact O-N 3.43Å; G45-L76 VanDerWaalsContact C-CD1 3.42Å
46F92.9Very high91.1Very high76 Ų7642.5 Ų42.533%0.33325%0.248SC..Hα-helixtrans-64.7-38.9176-172.5-84.8000111.8F42 D43 D44 L49 S50 Q75 L76 K79F42-F46 WeakPolarHBondContact O-CB 3.42Å; F42-F46 PolarHBondContact O-N 3.3Å; D43-F46 WeakPolarHBondContact O-CB 3.22Å; D43-F46 PolarHBondContact O-N 3.48Å; D44-F46 VanDerWaalsContact C-N 3.33Å; D44-F46 PolarHBondContact O-N 3.13Å; F46-L49 PolarHBondContact O-N 2.89Å; F46-S50 WeakPolarHBondContact CD1-OG 3.42Å; F46-S50 WeakPolarHBondContact CE1-OG 3.34Å; F46-S50 WeakPolarHBondContact O-CB 3.47Å; F46-S50 PolarHBondContact O-N 3.02Å; F46-S50 PolarHBondContact O-OG 3.09Å; F46-Q75 HydrophobicContact CE2-CB 4.48Å; F46-L76 HydrophobicContact CB-CD1 4.27Å; F46-K79 HydrophobicContact CD2-CB 3.96Å; F46-K79 HydrophobicContact CD2-CG 4.16Å; F46-K79 HydrophobicContact CE2-CB 3.58Å; F46-K79 HydrophobicContact CE2-CD 4.18Å; F46-K79 HydrophobicContact CE2-CG 3.78Å; F46-K79 HydrophobicContact CZ-CB 4.26Å; F46-K79 HydrophobicContact CZ-CD 3.99Å; F46-K79 HydrophobicContact CZ-CG 4Å
47A92.4Very high91.1Very high52 Ų5240.9 Ų40.943%0.4324%0.238SC..Hα-helixtrans-63.8-43.1175.700000111.9D43 D44 S50 S51D43-A47 PolarHBondContact O-N 3.14Å; D44-A47 WeakPolarHBondContact O-CB 3.47Å; D44-A47 PolarHBondContact O-N 2.64Å; A47-S50 PolarHBondContact O-N 2.81Å; A47-S51 PolarHBondContact O-N 2.96Å
48I93Very high91.1Very high29 Ų2939.1 Ų39.115%0.14923%0.229CC..Hα-helixtrans-58.9-50.5174.6-67.5162.6000110.3L5 I37 D44 G45 S50 S51 E53L5-I48 HydrophobicContact CD1-CD1 3.86Å; L5-I48 HydrophobicContact CD1-CG2 4.32Å; L5-I48 HydrophobicContact CD2-CB 4.47Å; L5-I48 HydrophobicContact CD2-CG2 4.11Å; I37-I48 HydrophobicContact CG2-CD1 4.02Å; D44-I48 WeakPolarHBondContact O-CG1 3.33Å; D44-I48 PolarHBondContact O-N 2.94Å; G45-I48 PolarHBondContact O-N 2.83Å; I48-S50 VanDerWaalsContact C-N 3.3Å; I48-S50 PolarHBondContact O-N 3.3Å; I48-S51 PolarHBondContact O-N 2.86Å; I48-S51 PolarHBondContact O-OG 2.84Å; I48-E53 HydrophobicContact CG2-CB 3.78Å; I48-E53 HydrophobicContact CG2-CG 4.16Å
49L92.8Very high91.2Very high6 Ų635.7 Ų35.73%0.03121%0.214CC..Hα-helixtrans-63.6-35.9177.1-65.3-178.4000112.5L5 G45 F46 S51 N52 I55 L76 K79 L80L5-L49 HydrophobicContact CD2-CD2 3.82Å; L5-L49 HydrophobicContact CD2-CG 3.99Å; G45-L49 WeakPolarHBondContact O-CG 3.47Å; G45-L49 PolarHBondContact O-N 3.43Å; F46-L49 PolarHBondContact O-N 2.89Å; L49-S51 VanDerWaalsContact C-N 3.27Å; L49-S51 PolarHBondContact O-N 2.83Å; L49-N52 WeakPolarHBondContact O-CA 3.28Å; L49-N52 PolarHBondContact O-N 2.88Å; L49-I55 HydrophobicContact CD2-CD1 3.79Å; L49-I55 HydrophobicContact CD2-CG1 4.48Å; L49-L76 HydrophobicContact CD1-CD1 3.57Å; L49-L76 HydrophobicContact CD1-CG 3.91Å; L49-L76 WeakPolarHBondContact CD1-O 3.36Å; L49-L76 HydrophobicContact CG-CD1 4.4Å; L49-K79 HydrophobicContact CB-CG 4.08Å; L49-L80 HydrophobicContact CD1-CB 3.92Å; L49-L80 HydrophobicContact CD2-CD1 3.83Å
50S88.7Confident91.1Very high19 Ų1935.7 Ų35.713%0.13321%0.214CC..Hα-helixtrans-69-23.7177.7-65.90000114F46 A47 I48 K79 R589F46-S50 WeakPolarHBondContact CD1-OG 3.42Å; F46-S50 WeakPolarHBondContact CE1-OG 3.34Å; F46-S50 WeakPolarHBondContact O-CB 3.47Å; F46-S50 PolarHBondContact O-N 3.02Å; F46-S50 PolarHBondContact O-OG 3.09Å; A47-S50 PolarHBondContact O-N 2.81Å; I48-S50 VanDerWaalsContact C-N 3.3Å; I48-S50 PolarHBondContact O-N 3.3Å; S50-K79 VanDerWaalsContact OG-CE 3.31Å; S50-K79 WeakPolarHBondContact OG-CE 3.37Å; S50-R589 PolarHBondContact O-NH1 3.08Å; S50-R589 PolarHBondContact O-NH2 3.36Å
51S86.7Confident91Very high81 Ų8131.4 Ų31.457%0.56619%0.188SC*.THydrogen-bonded Turntrans-79.3-1.7169.374.60000113.4A47 I48 L49A47-S51 PolarHBondContact O-N 2.96Å; I48-S51 PolarHBondContact O-N 2.86Å; I48-S51 PolarHBondContact O-OG 2.84Å; L49-S51 VanDerWaalsContact C-N 3.27Å; L49-S51 PolarHBondContact O-N 2.83Å
52N85.1Confident90.3Very high53 Ų5331 Ų3128%0.28318%0.183SC..THydrogen-bonded Turntrans66.834.3177.8-44.5-61.9000113.7L49 A54 R83L49-N52 WeakPolarHBondContact O-CA 3.28Å; L49-N52 PolarHBondContact O-N 2.88Å; N52-A54 PolarHBondContact O-N 3.16Å; N52-R83 VanDerWaalsContact CG-CZ 3.43Å; N52-R83 PolarHBondContact ND2-NH1 2.89Å; N52-R83 WeakPolarHBondContact OD1-CD 3.33Å; N52-R83 PolarHBondContact OD1-NE 3.21Å; N52-R83 VanDerWaalsContact OD1-NE 3.13Å; N52-R83 PolarHBondContact OD1-NH1 3.21Å
53E89.7Confident89.2Confident55 Ų5533.2 Ų33.226%0.25719%0.194SC..  trans-59121.6173.5-174.859.1-155.400110.1K3 I37 I48 I55 Q84K3-E53 IonicContact NZ-OE1 3.83Å; K3-E53 PolarHBondContact NZ-OE1 3.3Å; I37-E53 HydrophobicContact CD1-CG 3.66Å; I48-E53 HydrophobicContact CG2-CB 3.78Å; I48-E53 HydrophobicContact CG2-CG 4.16Å; E53-I55 HydrophobicContact CG-CG2 4.07Å; E53-I55 PolarHBondContact O-N 3.44Å; E53-Q84 PolarHBondContact O-NE2 2.8Å
54A90.7Very high88.1Confident64 Ų6429 Ų2953%0.52917%0.171SC..  trans-74.2110.1179.200000109.6K3 N52K3-A54 VanDerWaalsContact CD-O 3.23Å; K3-A54 WeakPolarHBondContact CD-O 3.26Å; N52-A54 PolarHBondContact O-N 3.16Å
55I94.1Very high86.8Confident2 Ų231.2 Ų31.21%0.0118%0.179CC..  trans-116.9151-179.663.2168.9000110.4L5 I37 L49 E53 L58 L80 Q84 V87L5-I55 HydrophobicContact CB-CD1 3.85Å; L5-I55 HydrophobicContact CB-CG2 4.13Å; L5-I55 HydrophobicContact CD2-CD1 4.32Å; I37-I55 HydrophobicContact CD1-CG2 4.39Å; L49-I55 HydrophobicContact CD2-CD1 3.79Å; L49-I55 HydrophobicContact CD2-CG1 4.48Å; E53-I55 HydrophobicContact CG-CG2 4.07Å; E53-I55 PolarHBondContact O-N 3.44Å; I55-L58 HydrophobicContact CD1-CB 4.16Å; I55-L80 HydrophobicContact CD1-CD1 3.77Å; I55-L80 HydrophobicContact CG1-CD1 4Å; I55-Q84 VanDerWaalsContact N-OE1 3.12Å; I55-Q84 PolarHBondContact O-OE1 3.23Å; I55-Q84 VanDerWaalsContact O-OE1 3.09Å; I55-V87 HydrophobicContact CD1-CG1 4.37Å; I55-V87 HydrophobicContact CG1-CG1 4.24Å; I55-V87 WeakPolarHBondContact O-CG2 3.5Å
56D95.1Very high85.7Confident11 Ų1134.7 Ų34.76%0.05920%0.195CC..SBendtrans-99.9-13.3177.8-59-79000112.2M2 K3 P88 M132 Y135 R136M2-D56 VanDerWaalsContact CA-OD2 3.25Å; M2-D56 WeakPolarHBondContact CA-OD2 3.34Å; K3-D56 PolarHBondContact N-OD2 3.05Å; K3-D56 WeakPolarHBondContact O-CA 3.5Å; K3-D56 WeakPolarHBondContact O-CB 3.45Å; K3-D56 PolarHBondContact O-N 3.24Å; D56-P88 WeakPolarHBondContact O-CD 3.32Å; D56-P88 WeakPolarHBondContact O-CG 3.43Å; D56-M132 HydrophobicContact CB-CB 4Å; D56-M132 HydrophobicContact CB-CG 3.67Å; D56-M132 HydrophobicContact CB-SD 3.81Å; D56-M132 WeakPolarHBondContact O-CG 3.49Å; D56-Y135 HydrophobicContact CB-CD1 4.37Å; D56-R136 VanDerWaalsContact CG-NH2 3.32Å; D56-R136 IonicContact OD1-CZ 3.94Å; D56-R136 IonicContact OD1-NE 3.93Å; D56-R136 PolarHBondContact OD1-NE 3.49Å; D56-R136 IonicContact OD1-NH2 2.83Å; D56-R136 PolarHBondContact OD1-NH2 2.91Å; D56-R136 VanDerWaalsContact OD1-NH2 3.15Å; D56-R136 IonicContact OD2-CZ 3.32Å; D56-R136 IonicContact OD2-NE 2.97Å; D56-R136 IonicContact OD2-NH2 3.53Å; D56-R136 PolarHBondContact OD2-NH2 3.07Å
57C96.2Very high84.6Confident0 Ų035.9 Ų35.90%021%0.21CC..EExtended strand (participates in β ladder)trans-159.3140.9177.1178.80000110.5K3 V4 L5 P88 F90 M132K3-C57 PolarHBondContact O-N 3.26Å; V4-C57 WeakPolarHBondContact CA-O 3.37Å; V4-C57 HydrophobicContact CB-CB 4.4Å; V4-C57 HydrophobicContact CG2-CB 3.94Å; L5-C57 PolarHBondContact N-O 2.86Å; C57-P88 WeakPolarHBondContact CA-O 3.48Å; C57-P88 HydrophobicContact CB-CG 4.13Å; C57-P88 PolarHBondContact SG-O 3.31Å; C57-P88 VanDerWaalsContact SG-O 3.35Å; C57-F90 VanDerWaalsContact SG-CD2 3.56Å; C57-M132 HydrophobicContact CB-CG 3.65Å; C57-M132 HydrophobicContact CB-SD 3.98Å
58L95.8Very high83.8Confident0 Ų038.7 Ų38.70%022%0.218CC..EExtended strand (participates in β ladder)trans-105.5128.8167.1174.264.6000108.9L5 V7 I55 L76 I77 L80 P88 V89 F90L5-L58 HydrophobicContact CB-CD1 4.23Å; L5-L58 HydrophobicContact CD2-CD1 3.98Å; L5-L58 HydrophobicContact CG-CD1 4Å; V7-L58 HydrophobicContact CG2-CD1 3.88Å; I55-L58 HydrophobicContact CD1-CB 4.16Å; L58-L76 HydrophobicContact CD1-CD2 4.23Å; L58-L76 HydrophobicContact CD2-CD2 4.06Å; L58-L76 HydrophobicContact CD2-CG 4.36Å; L58-I77 HydrophobicContact CD2-CG1 4.2Å; L58-L80 HydrophobicContact CB-CD2 3.89Å; L58-L80 HydrophobicContact CD2-CD2 3.83Å; L58-P88 PolarHBondContact N-O 2.97Å; L58-V89 HydrophobicContact CB-CG2 4.42Å; L58-V89 HydrophobicContact CD2-CG1 4.41Å; L58-V89 HydrophobicContact CD2-CG2 4.45Å; L58-V89 CarbonylContact O-C 2.9Å; L58-V89 WeakPolarHBondContact O-CA 3.48Å; L58-F90 PolarHBondContact O-N 3.26Å
59M94.3Very high82.9Confident0 Ų037.4 Ų37.40%021%0.211CC..EExtended strand (participates in β ladder)trans-119.4138.7168.9-52.4-172.1164.900108.7V4 L5 I6 V7 L25 L29 F90 L92 A128V4-M59 HydrophobicContact CG2-CE 4.07Å; V4-M59 HydrophobicContact CG2-CG 3.76Å; V4-M59 HydrophobicContact CG2-SD 4Å; L5-M59 PolarHBondContact O-N 3.16Å; I6-M59 CarbonylContact C-O 3.55Å; I6-M59 WeakPolarHBondContact CA-O 3.24Å; I6-M59 HydrophobicContact CG1-CB 4.25Å; I6-M59 HydrophobicContact CG1-SD 4.34Å; V7-M59 PolarHBondContact N-O 2.86Å; L25-M59 HydrophobicContact CD2-SD 3.94Å; L29-M59 HydrophobicContact CD1-CE 4.21Å; L29-M59 HydrophobicContact CD1-SD 4.1Å; L29-M59 HydrophobicContact CD2-CE 4.47Å; M59-F90 WeakPolarHBondContact CA-O 3.39Å; M59-F90 HydrophobicContact CB-CB 4.4Å; M59-F90 HydrophobicContact CE-CG 4.49Å; M59-F90 HydrophobicContact CG-CB 4.02Å; M59-L92 HydrophobicContact CB-CD1 3.96Å; M59-L92 HydrophobicContact CB-CD2 4.31Å; M59-L92 HydrophobicContact CB-CG 4.08Å; M59-L92 HydrophobicContact SD-CD2 4.34Å; M59-A128 HydrophobicContact CE-CB 3.21Å
60F89.8Confident82.2Confident0 Ų039.2 Ų39.20%022%0.22CC..EExtended strand (participates in β ladder)trans-141.3148175.868.3-80000112.2V7 F42 Y62 V73 I77 V89 F90 L91 L92 L106 V110V7-F60 HydrophobicContact CB-CB 4.21Å; V7-F60 VanDerWaalsContact O-CA 3.22Å; V7-F60 WeakPolarHBondContact O-CA 3.33Å; F42-F60 HydrophobicContact CE1-CB 4.39Å; F42-F60 HydrophobicContact CE1-CD2 4.39Å; F42-F60 HydrophobicContact CZ-CD2 4.48Å; F60-Y62 AromaticContact CD2-CD1 3.84Å; F60-Y62 HydrophobicContact CD2-CD1 3.84Å; F60-Y62 HydrophobicContact CD2-CE1 4.18Å; F60-Y62 AromaticContact CE2-CD1 3.74Å; F60-Y62 HydrophobicContact CE2-CD1 3.74Å; F60-Y62 AromaticContact CE2-CE1 3.58Å; F60-Y62 HydrophobicContact CE2-CE1 3.58Å; F60-V73 HydrophobicContact CD2-CG1 4.08Å; F60-V73 HydrophobicContact CD2-CG2 3.79Å; F60-V73 HydrophobicContact CE1-CG1 4.44Å; F60-V73 HydrophobicContact CE2-CB 4.2Å; F60-V73 HydrophobicContact CE2-CG1 3.36Å; F60-V73 HydrophobicContact CE2-CG2 3.67Å; F60-V73 HydrophobicContact CZ-CG1 3.6Å; F60-I77 HydrophobicContact CE1-CD1 4.11Å; F60-I77 HydrophobicContact CZ-CD1 4.23Å; F60-V89 HydrophobicContact CD1-CG1 4.08Å; F60-V89 HydrophobicContact CE1-CG1 3.58Å; F60-F90 WeakPolarHBondContact CD1-O 3.25Å; F60-F90 PolarHBondContact N-O 3.45Å; F60-L91 HydrophobicContact CD2-CD1 3.88Å; F60-L91 HydrophobicContact CE1-CB 4.41Å; F60-L91 HydrophobicContact CE1-CD1 4.35Å; F60-L91 HydrophobicContact CE2-CD1 3.32Å; F60-L91 HydrophobicContact CZ-CB 4.21Å; F60-L91 HydrophobicContact CZ-CD1 3.59Å; F60-L91 HydrophobicContact CZ-CG 4.47Å; F60-L92 WeakPolarHBondContact O-CB 3.42Å; F60-L92 PolarHBondContact O-N 3.24Å; F60-L106 HydrophobicContact CZ-CD1 4.45Å; F60-V110 HydrophobicContact CE1-CG2 4.1Å; F60-V110 HydrophobicContact CZ-CG2 3.94Å
61S82.4Confident81.9Confident4 Ų443.5 Ų43.53%0.02824%0.238CC..EExtended strand (participates in β ladder)trans-128.5133.7175.4-163.10000110.5V7 S9 L92V7-S61 PolarHBondContact O-N 2.89Å; S9-S61 WeakPolarHBondContact CB-O 3.4Å; S9-S61 PolarHBondContact N-O 3.47Å; S61-L92 WeakPolarHBondContact CA-O 3.35Å; S61-L92 WeakPolarHBondContact CB-O 3.4Å; S61-L92 PolarHBondContact OG-O 3.45Å
62Y74.7Confident81.9Confident11 Ų1141.6 Ų41.64%0.04322%0.221CC..  trans-149.2157.1174.873.6-70.8000111.6F42 F60 M64 E69 H70 V73 L91 L106F42-Y62 HydrophobicContact CZ-CG 4.38Å; F60-Y62 AromaticContact CD2-CD1 3.84Å; F60-Y62 HydrophobicContact CD2-CD1 3.84Å; F60-Y62 HydrophobicContact CD2-CE1 4.18Å; F60-Y62 AromaticContact CE2-CD1 3.74Å; F60-Y62 HydrophobicContact CE2-CD1 3.74Å; F60-Y62 AromaticContact CE2-CE1 3.58Å; F60-Y62 HydrophobicContact CE2-CE1 3.58Å; Y62-M64 VanDerWaalsContact C-N 3.31Å; Y62-M64 HydrophobicContact CD1-CE 4.37Å; Y62-M64 HydrophobicContact CD2-CB 4.38Å; Y62-M64 HydrophobicContact CD2-CG 3.85Å; Y62-M64 HydrophobicContact CE1-CE 3.55Å; Y62-M64 HydrophobicContact CE1-CG 4.19Å; Y62-M64 HydrophobicContact CE2-CB 4.07Å; Y62-M64 HydrophobicContact CE2-CE 4.4Å; Y62-M64 HydrophobicContact CE2-CG 3.52Å; Y62-M64 HydrophobicContact CG-CG 4.37Å; Y62-M64 PolarHBondContact O-N 3.01Å; Y62-E69 HydrophobicContact CD2-CB 3.52Å; Y62-E69 HydrophobicContact CD2-CG 4.26Å; Y62-E69 WeakPolarHBondContact CD2-OE2 3.36Å; Y62-E69 HydrophobicContact CE2-CB 4.09Å; Y62-E69 HydrophobicContact CG-CB 4.37Å; Y62-H70 AromaticContact CE2-CE1 3.74Å; Y62-H70 AromaticContact CE2-ND1 3.65Å; Y62-H70 AromaticContact CZ-ND1 3.79Å; Y62-H70 PolarHBondContact OH-CE1 3.29Å; Y62-H70 PolarHBondContact OH-ND1 2.94Å; Y62-V73 HydrophobicContact CD1-CG2 3.97Å; Y62-V73 HydrophobicContact CE1-CG2 4.02Å; Y62-V73 HydrophobicContact CG-CG2 4.29Å; Y62-L91 HydrophobicContact CD1-CD1 3.99Å; Y62-L91 HydrophobicContact CE1-CD1 3.71Å; Y62-L106 VanDerWaalsContact OH-CD2 3.28Å; Y62-L106 WeakPolarHBondContact OH-CD2 3.23Å
63Q65.6Low82Confident54 Ų5439 Ų3925%0.25221%0.208SC..  trans-81.1-14.3-169.2-68.7-177.6-4.600113F11 E65 E69F11-Q63 PolarHBondContact O-NE2 3.47Å; Q63-E65 HydrophobicContact CB-CG 4.33Å; Q63-E65 PolarHBondContact O-N 2.95Å; Q63-E69 PolarHBondContact N-OE2 3.2Å
64M65.1Low81.9Confident26 Ų2640.6 Ų40.613%0.12821%0.211CC..SBendtrans62.522.4-179.2-48.8-161.7167.300113.4Y62 E69 L91 A98 A101Y62-M64 VanDerWaalsContact C-N 3.31Å; Y62-M64 HydrophobicContact CD1-CE 4.37Å; Y62-M64 HydrophobicContact CD2-CB 4.38Å; Y62-M64 HydrophobicContact CD2-CG 3.85Å; Y62-M64 HydrophobicContact CE1-CE 3.55Å; Y62-M64 HydrophobicContact CE1-CG 4.19Å; Y62-M64 HydrophobicContact CE2-CB 4.07Å; Y62-M64 HydrophobicContact CE2-CE 4.4Å; Y62-M64 HydrophobicContact CE2-CG 3.52Å; Y62-M64 HydrophobicContact CG-CG 4.37Å; Y62-M64 PolarHBondContact O-N 3.01Å; M64-E69 PolarHBondContact N-OE2 3.39Å; M64-L91 HydrophobicContact CE-CD1 4.19Å; M64-L91 HydrophobicContact CE-CD2 3.7Å; M64-A98 HydrophobicContact CE-CB 4.11Å; M64-A98 VanDerWaalsContact SD-CA 3.58Å; M64-A101 HydrophobicContact CB-CB 4Å; M64-A101 HydrophobicContact CG-CB 4.45Å; M64-A101 HydrophobicContact SD-CB 3.65Å
65E65.2Low81.9Confident112 Ų11242 Ų4252%0.52321%0.207SC..  trans-98.2-19-177.3-68-178.3-167.900111.9Q63 K97Q63-E65 HydrophobicContact CB-CG 4.33Å; Q63-E65 PolarHBondContact O-N 2.95Å; E65-K97 IonicContact OE1-NZ 3.39Å; E65-K97 PolarHBondContact OE1-NZ 2.59Å
66H68.6Low81.7Confident73 Ų7342 Ų4234%0.33821%0.207SC..  trans-117.7124.9-175.4-60.6-55.8000111.1F11 D68 E69F11-H66 AromaticContact CD2-CD2 3.9Å; F11-H66 AromaticContact CE2-CD2 3.84Å; H66-D68 PolarHBondContact O-N 3.43Å; H66-D68 VanDerWaalsContact O-N 3.12Å; H66-E69 HydrophobicContact CB-CG 4.12Å; H66-E69 WeakPolarHBondContact O-CB 3.38Å; H66-E69 PolarHBondContact O-N 3.37Å
67P70.6Confident81.6Confident101 Ų10141.5 Ų41.566%0.65620%0.204SC*.Hα-helixtrans-52.1-34.1175.6-28.435.4000113.7E69 H70 Q71P67-E69 VanDerWaalsContact C-N 3.29Å; P67-E69 PolarHBondContact O-N 2.96Å; P67-H70 PolarHBondContact O-N 3.44Å; P67-Q71 PolarHBondContact O-N 3.01Å
68D75.7Confident81.3Confident111 Ų11143.1 Ų43.159%0.59422%0.221SC*.Hα-helixtrans-63.7-32.8179.1-58-24.5000112H66 H70 Q71 N72H66-D68 PolarHBondContact O-N 3.43Å; H66-D68 VanDerWaalsContact O-N 3.12Å; D68-H70 VanDerWaalsContact C-N 3.33Å; D68-H70 PolarHBondContact O-N 3.03Å; D68-Q71 PolarHBondContact O-N 3.38Å; D68-N72 WeakPolarHBondContact O-CB 3.21Å; D68-N72 PolarHBondContact O-N 3.44Å; D68-N72 PolarHBondContact O-ND2 3.46Å; D68-N72 PolarHBondContact O-OD1 3.33Å
69E75.1Confident81.2Confident2 Ų244.8 Ų44.81%0.00923%0.228CC..Hα-helixtrans-63.3-39.4176.6-70.8-176134.600111.4S9 F11 Y62 Q63 M64 H66 P67 Q71 N72 V73S9-E69 WeakPolarHBondContact CB-OE1 3.31Å; S9-E69 PolarHBondContact OG-OE1 3.19Å; F11-E69 HydrophobicContact CD2-CG 4.33Å; F11-E69 WeakPolarHBondContact CD2-OE1 3.43Å; F11-E69 HydrophobicContact CE2-CG 4.27Å; Y62-E69 HydrophobicContact CD2-CB 3.52Å; Y62-E69 HydrophobicContact CD2-CG 4.26Å; Y62-E69 WeakPolarHBondContact CD2-OE2 3.36Å; Y62-E69 HydrophobicContact CE2-CB 4.09Å; Y62-E69 HydrophobicContact CG-CB 4.37Å; Q63-E69 PolarHBondContact N-OE2 3.2Å; M64-E69 PolarHBondContact N-OE2 3.39Å; H66-E69 HydrophobicContact CB-CG 4.12Å; H66-E69 WeakPolarHBondContact O-CB 3.38Å; H66-E69 PolarHBondContact O-N 3.37Å; P67-E69 VanDerWaalsContact C-N 3.29Å; P67-E69 PolarHBondContact O-N 2.96Å; E69-Q71 VanDerWaalsContact C-N 3.31Å; E69-Q71 PolarHBondContact O-N 3.22Å; E69-N72 PolarHBondContact O-N 3.16Å; E69-V73 VanDerWaalsContact O-CG2 3.27Å; E69-V73 WeakPolarHBondContact O-CG2 3.35Å; E69-V73 PolarHBondContact O-N 3.2Å
70H77.4Confident81.1Confident45 Ų4544.9 Ų44.921%0.20823%0.228CC..Hα-helixtrans-62.9-39.9177.3-67.4-68.5000111.8Y62 P67 D68 R74Y62-H70 AromaticContact CE2-CE1 3.74Å; Y62-H70 AromaticContact CE2-ND1 3.65Å; Y62-H70 AromaticContact CZ-ND1 3.79Å; Y62-H70 PolarHBondContact OH-CE1 3.29Å; Y62-H70 PolarHBondContact OH-ND1 2.94Å; P67-H70 PolarHBondContact O-N 3.44Å; D68-H70 VanDerWaalsContact C-N 3.33Å; D68-H70 PolarHBondContact O-N 3.03Å; H70-R74 WeakPolarHBondContact O-CG 3.31Å; H70-R74 PolarHBondContact O-N 2.91Å
71Q82.8Confident81.1Confident108 Ų10846.5 Ų46.551%0.50524%0.236SC..Hα-helixtrans-67.7-43.3176.5-178.1172.2-15.400111.3P67 D68 E69 R74 Q75P67-Q71 PolarHBondContact O-N 3.01Å; D68-Q71 PolarHBondContact O-N 3.38Å; E69-Q71 VanDerWaalsContact C-N 3.31Å; E69-Q71 PolarHBondContact O-N 3.22Å; Q71-R74 PolarHBondContact O-N 3.24Å; Q71-Q75 WeakPolarHBondContact O-CG 3.43Å; Q71-Q75 PolarHBondContact O-N 3.33Å
72N86.5Confident81.5Confident41 Ų4149.9 Ų49.922%0.21925%0.251CS..Hα-helixtrans-63.8-41.9179.8-68.8-10.2000112F42 D68 E69 R74 Q75 L76F42-N72 HydrophobicContact CB-CB 3.9Å; F42-N72 HydrophobicContact CD1-CB 4.49Å; F42-N72 HydrophobicContact CD2-CB 4.3Å; F42-N72 HydrophobicContact CG-CB 3.97Å; D68-N72 WeakPolarHBondContact O-CB 3.21Å; D68-N72 PolarHBondContact O-N 3.44Å; D68-N72 PolarHBondContact O-ND2 3.46Å; D68-N72 PolarHBondContact O-OD1 3.33Å; E69-N72 PolarHBondContact O-N 3.16Å; N72-R74 VanDerWaalsContact C-N 3.33Å; N72-R74 PolarHBondContact O-N 2.87Å; N72-Q75 PolarHBondContact O-N 2.89Å; N72-L76 WeakPolarHBondContact O-CB 3.44Å; N72-L76 PolarHBondContact O-N 2.75Å
73V86.5Confident82.1Confident0 Ų051.9 Ų51.90%026%0.259CS..Hα-helixtrans-58.9-44.8173.7168.40000111.1F42 F60 Y62 E69 L76 I77 L106F42-V73 HydrophobicContact CD1-CG2 4.36Å; F42-V73 HydrophobicContact CE1-CG2 3.49Å; F42-V73 VanDerWaalsContact CE1-CG2 3.49Å; F42-V73 HydrophobicContact CE2-CG2 4.4Å; F42-V73 HydrophobicContact CZ-CG2 3.51Å; F60-V73 HydrophobicContact CD2-CG1 4.08Å; F60-V73 HydrophobicContact CD2-CG2 3.79Å; F60-V73 HydrophobicContact CE1-CG1 4.44Å; F60-V73 HydrophobicContact CE2-CB 4.2Å; F60-V73 HydrophobicContact CE2-CG1 3.36Å; F60-V73 HydrophobicContact CE2-CG2 3.67Å; F60-V73 HydrophobicContact CZ-CG1 3.6Å; Y62-V73 HydrophobicContact CD1-CG2 3.97Å; Y62-V73 HydrophobicContact CE1-CG2 4.02Å; Y62-V73 HydrophobicContact CG-CG2 4.29Å; E69-V73 VanDerWaalsContact O-CG2 3.27Å; E69-V73 WeakPolarHBondContact O-CG2 3.35Å; E69-V73 PolarHBondContact O-N 3.2Å; V73-L76 PolarHBondContact O-N 2.82Å; V73-I77 HydrophobicContact CG1-CD1 3.73Å; V73-I77 HydrophobicContact CG1-CG1 4.44Å; V73-I77 WeakPolarHBondContact O-CG1 3.27Å; V73-I77 PolarHBondContact O-N 3.22Å; V73-L106 HydrophobicContact CG1-CD1 3.79Å
74R87.4Confident83.3Confident88 Ų8850.5 Ų50.533%0.33225%0.252SS..Hα-helixtrans-64.4-41.5178.1-73.7174.5178.1157.83.6112.3H70 Q71 N72 L76 G78 D103 L109H70-R74 WeakPolarHBondContact O-CG 3.31Å; H70-R74 PolarHBondContact O-N 2.91Å; Q71-R74 PolarHBondContact O-N 3.24Å; N72-R74 VanDerWaalsContact C-N 3.33Å; N72-R74 PolarHBondContact O-N 2.87Å; R74-L76 VanDerWaalsContact C-N 3.35Å; R74-G78 PolarHBondContact O-N 3.06Å; R74-D103 IonicContact CZ-OD2 3.62Å; R74-D103 IonicContact NH2-OD1 3.24Å; R74-D103 PolarHBondContact NH2-OD1 3.32Å; R74-D103 IonicContact NH2-OD2 3.69Å; R74-D103 PolarHBondContact NH2-OD2 3.27Å; R74-L109 HydrophobicContact CG-CD1 4.3Å
75Q90.2Very high84.2Confident94 Ų9453.5 Ų53.544%0.43927%0.266SS..Hα-helixtrans-64.6-40.9176-72.7-179.6-8.200111.5F46 Q71 N72 K79F46-Q75 HydrophobicContact CE2-CB 4.48Å; Q71-Q75 WeakPolarHBondContact O-CG 3.43Å; Q71-Q75 PolarHBondContact O-N 3.33Å; N72-Q75 PolarHBondContact O-N 2.89Å; Q75-K79 VanDerWaalsContact O-CB 3.31Å; Q75-K79 WeakPolarHBondContact O-CB 3.19Å; Q75-K79 PolarHBondContact O-N 2.94Å
76L91.6Very high85.3Confident1 Ų153.2 Ų53.21%0.00527%0.268CS..Hα-helixtrans-61.8-52.4176.3-175.878.1000111.8V7 F42 G45 F46 L49 L58 N72 V73 R74 K79 L80V7-L76 HydrophobicContact CB-CD2 4.18Å; V7-L76 HydrophobicContact CG1-CD2 4.18Å; V7-L76 HydrophobicContact CG2-CD2 3.93Å; F42-L76 HydrophobicContact CD1-CD2 4.04Å; F42-L76 HydrophobicContact CE1-CD2 4.23Å; G45-L76 VanDerWaalsContact C-CD1 3.42Å; F46-L76 HydrophobicContact CB-CD1 4.27Å; L49-L76 HydrophobicContact CD1-CD1 3.57Å; L49-L76 HydrophobicContact CD1-CG 3.91Å; L49-L76 WeakPolarHBondContact CD1-O 3.36Å; L49-L76 HydrophobicContact CG-CD1 4.4Å; L58-L76 HydrophobicContact CD1-CD2 4.23Å; L58-L76 HydrophobicContact CD2-CD2 4.06Å; L58-L76 HydrophobicContact CD2-CG 4.36Å; N72-L76 WeakPolarHBondContact O-CB 3.44Å; N72-L76 PolarHBondContact O-N 2.75Å; V73-L76 PolarHBondContact O-N 2.82Å; R74-L76 VanDerWaalsContact C-N 3.35Å; L76-K79 PolarHBondContact O-N 3Å; L76-L80 PolarHBondContact O-N 3.38Å
77I91.5Very high86.5Confident0 Ų049.8 Ų49.80%025%0.252CS..Hα-helixtrans-66.4-40.3179.7-61.4168.6000110.5L58 F60 V73 K79 L80 H81 V89 L109L58-I77 HydrophobicContact CD2-CG1 4.2Å; F60-I77 HydrophobicContact CE1-CD1 4.11Å; F60-I77 HydrophobicContact CZ-CD1 4.23Å; V73-I77 HydrophobicContact CG1-CD1 3.73Å; V73-I77 HydrophobicContact CG1-CG1 4.44Å; V73-I77 WeakPolarHBondContact O-CG1 3.27Å; V73-I77 PolarHBondContact O-N 3.22Å; I77-K79 VanDerWaalsContact C-N 3.3Å; I77-K79 PolarHBondContact O-N 2.95Å; I77-L80 WeakPolarHBondContact O-CB 3.33Å; I77-L80 PolarHBondContact O-N 3.21Å; I77-H81 WeakPolarHBondContact CG2-CE1 3.49Å; I77-H81 PolarHBondContact O-N 3.43Å; I77-V89 HydrophobicContact CD1-CG1 4.02Å; I77-V89 HydrophobicContact CG1-CG1 4.26Å; I77-V89 HydrophobicContact CG2-CG2 4.43Å; I77-L109 HydrophobicContact CD1-CB 4.03Å; I77-L109 HydrophobicContact CG2-CB 4.13Å; I77-L109 HydrophobicContact CG2-CD2 4.02Å; I77-L109 HydrophobicContact CG2-CG 4.46Å
78G91.1Very high87.7Confident34 Ų3445.5 Ų45.535%0.35122%0.224SC..Hα-helixtrans-56-45.917300000111.6R74 L80 H81 E82R74-G78 PolarHBondContact O-N 3.06Å; G78-L80 PolarHBondContact O-N 3.38Å; G78-H81 PolarHBondContact O-N 3.04Å; G78-E82 PolarHBondContact O-N 2.8Å
79K92.7Very high88.6Confident35 Ų3540.2 Ų40.215%0.15220%0.196CC..Hα-helixtrans-64-39.4177.8-172.259.4-179.5172.50112.9F46 L49 S50 Q75 L76 I77 E82F46-K79 HydrophobicContact CD2-CB 3.96Å; F46-K79 HydrophobicContact CD2-CG 4.16Å; F46-K79 HydrophobicContact CE2-CB 3.58Å; F46-K79 HydrophobicContact CE2-CD 4.18Å; F46-K79 HydrophobicContact CE2-CG 3.78Å; F46-K79 HydrophobicContact CZ-CB 4.26Å; F46-K79 HydrophobicContact CZ-CD 3.99Å; F46-K79 HydrophobicContact CZ-CG 4Å; L49-K79 HydrophobicContact CB-CG 4.08Å; S50-K79 VanDerWaalsContact OG-CE 3.31Å; S50-K79 WeakPolarHBondContact OG-CE 3.37Å; Q75-K79 VanDerWaalsContact O-CB 3.31Å; Q75-K79 WeakPolarHBondContact O-CB 3.19Å; Q75-K79 PolarHBondContact O-N 2.94Å; L76-K79 PolarHBondContact O-N 3Å; I77-K79 VanDerWaalsContact C-N 3.3Å; I77-K79 PolarHBondContact O-N 2.95Å; K79-E82 WeakPolarHBondContact CD-OE2 3.41Å; K79-E82 IonicContact NZ-OE1 3.27Å; K79-E82 IonicContact NZ-OE2 3.99Å; K79-E82 PolarHBondContact NZ-OE2 3.25Å
80L92.6Very high89.5Confident2 Ų240.1 Ų40.11%0.0120%0.196CC..Hα-helixtrans-58.2-50.5172.9178.164.1000110.9L49 I55 L58 L76 I77 G78 E82 R83 Q84 V87 V89L49-L80 HydrophobicContact CD1-CB 3.92Å; L49-L80 HydrophobicContact CD2-CD1 3.83Å; I55-L80 HydrophobicContact CD1-CD1 3.77Å; I55-L80 HydrophobicContact CG1-CD1 4Å; L58-L80 HydrophobicContact CB-CD2 3.89Å; L58-L80 HydrophobicContact CD2-CD2 3.83Å; L76-L80 PolarHBondContact O-N 3.38Å; I77-L80 WeakPolarHBondContact O-CB 3.33Å; I77-L80 PolarHBondContact O-N 3.21Å; G78-L80 PolarHBondContact O-N 3.38Å; L80-E82 PolarHBondContact O-N 3.22Å; L80-R83 PolarHBondContact O-N 2.67Å; L80-Q84 HydrophobicContact CD1-CB 3.93Å; L80-Q84 WeakPolarHBondContact O-CA 3.31Å; L80-Q84 PolarHBondContact O-N 3.39Å; L80-V87 HydrophobicContact CD1-CB 4.24Å; L80-V87 HydrophobicContact CD1-CG1 4.28Å; L80-V87 HydrophobicContact CD1-CG2 4.4Å; L80-V87 HydrophobicContact CD2-CB 4Å; L80-V87 HydrophobicContact CD2-CG1 3.91Å; L80-V87 HydrophobicContact CG-CB 4.32Å; L80-V89 HydrophobicContact CD2-CG2 3.98Å
81H90.8Very high90Very high35 Ų3538 Ų3816%0.16219%0.186CC..Hα-helixtrans-74.2-8.6-172.9-65.8171.4000114.6I77 G78 R83 N442I77-H81 WeakPolarHBondContact CG2-CE1 3.49Å; I77-H81 PolarHBondContact O-N 3.43Å; G78-H81 PolarHBondContact O-N 3.04Å; H81-R83 VanDerWaalsContact C-N 3.29Å; H81-R83 PolarHBondContact O-N 2.96Å; H81-N442 PolarHBondContact O-ND2 3.02Å
82E90.1Very high90.2Very high75 Ų7532.9 Ų32.935%0.3516%0.162SC..THydrogen-bonded Turntrans-61.1-37.8169-74.8176.6-168.900112G78 K79 L80 N442 S443 S446G78-E82 PolarHBondContact O-N 2.8Å; K79-E82 WeakPolarHBondContact CD-OE2 3.41Å; K79-E82 IonicContact NZ-OE1 3.27Å; K79-E82 IonicContact NZ-OE2 3.99Å; K79-E82 PolarHBondContact NZ-OE2 3.25Å; L80-E82 PolarHBondContact O-N 3.22Å; E82-N442 CarbonylContact O-C 3.48Å; E82-N442 VanDerWaalsContact O-C 3.23Å; E82-S443 WeakPolarHBondContact O-CA 3.38Å; E82-S443 PolarHBondContact O-N 3.5Å; E82-S446 WeakPolarHBondContact O-CB 3.18Å
83R87Confident89.8Confident52 Ų5231.3 Ų31.320%0.19616%0.156CC..THydrogen-bonded Turntrans-120.6-26.4-177.7-67.3-172.6179.4-160.25.5113.9N52 L80 H81 S446 E450N52-R83 VanDerWaalsContact CG-CZ 3.43Å; N52-R83 PolarHBondContact ND2-NH1 2.89Å; N52-R83 WeakPolarHBondContact OD1-CD 3.33Å; N52-R83 PolarHBondContact OD1-NE 3.21Å; N52-R83 VanDerWaalsContact OD1-NE 3.13Å; N52-R83 PolarHBondContact OD1-NH1 3.21Å; L80-R83 PolarHBondContact O-N 2.67Å; H81-R83 VanDerWaalsContact C-N 3.29Å; H81-R83 PolarHBondContact O-N 2.96Å; R83-S446 WeakPolarHBondContact CG-OG 2.98Å; R83-S446 PolarHBondContact NE-OG 3.35Å; R83-E450 IonicContact CZ-OE1 2.97Å; R83-E450 IonicContact CZ-OE2 3.67Å; R83-E450 IonicContact NH1-OE1 3.66Å; R83-E450 IonicContact NH2-OE1 3.26Å; R83-E450 PolarHBondContact NH2-OE1 2.95Å; R83-E450 IonicContact NH2-OE2 3.9Å; R83-E450 PolarHBondContact NH2-OE2 2.9Å
84Q89.8Confident89.1Confident25 Ų2534.5 Ų34.512%0.11717%0.173CC..  trans-12856.9-172-52.5-177.853.500110.1E53 I55 L80 N86 V87E53-Q84 PolarHBondContact O-NE2 2.8Å; I55-Q84 VanDerWaalsContact N-OE1 3.12Å; I55-Q84 PolarHBondContact O-OE1 3.23Å; I55-Q84 VanDerWaalsContact O-OE1 3.09Å; L80-Q84 HydrophobicContact CD1-CB 3.93Å; L80-Q84 WeakPolarHBondContact O-CA 3.31Å; L80-Q84 PolarHBondContact O-N 3.39Å; Q84-N86 PolarHBondContact O-N 2.9Å; Q84-V87 HydrophobicContact CB-CB 4.41Å; Q84-V87 HydrophobicContact CB-CG2 3.54Å; Q84-V87 HydrophobicContact CG-CG2 4.49Å; Q84-V87 PolarHBondContact O-N 3.24Å; Q84-V87 VanDerWaalsContact O-N 3.16Å
85Q85.4Confident88.3Confident90 Ų9036.1 Ų36.142%0.42118%0.179SC..THydrogen-bonded Turntrans-53.1-29.3-168.9-175.4175-9.700115.7
86N88.4Confident87.2Confident106 Ų10639.4 Ų39.457%0.56719%0.194SC*.THydrogen-bonded Turntrans-111.215.2-173.8-58.4-39000113.2Q84 Y135Q84-N86 PolarHBondContact O-N 2.9Å; N86-Y135 HydrophobicContact CB-CD2 4.26Å; N86-Y135 HydrophobicContact CB-CE2 4.24Å; N86-Y135 WeakPolarHBondContact O-CD2 3.31Å
87V93.2Very high85.9Confident0 Ų043.9 Ų43.90%021%0.214CC..  trans-66.4127.8176166.10000109I55 L80 Q84 V89 Y135I55-V87 HydrophobicContact CD1-CG1 4.37Å; I55-V87 HydrophobicContact CG1-CG1 4.24Å; I55-V87 WeakPolarHBondContact O-CG2 3.5Å; L80-V87 HydrophobicContact CD1-CB 4.24Å; L80-V87 HydrophobicContact CD1-CG1 4.28Å; L80-V87 HydrophobicContact CD1-CG2 4.4Å; L80-V87 HydrophobicContact CD2-CB 4Å; L80-V87 HydrophobicContact CD2-CG1 3.91Å; L80-V87 HydrophobicContact CG-CB 4.32Å; Q84-V87 HydrophobicContact CB-CB 4.41Å; Q84-V87 HydrophobicContact CB-CG2 3.54Å; Q84-V87 HydrophobicContact CG-CG2 4.49Å; Q84-V87 PolarHBondContact O-N 3.24Å; Q84-V87 VanDerWaalsContact O-N 3.16Å; V87-V89 PolarHBondContact O-N 3.01Å; V87-Y135 HydrophobicContact CG2-CE1 3.76Å; V87-Y135 HydrophobicContact CG2-CE2 3.95Å; V87-Y135 VanDerWaalsContact CG2-CZ 3.42Å; V87-Y135 WeakPolarHBondContact CG2-OH 3.45Å
88P95.1Very high84.6Confident11 Ų1144 Ų447%0.07121%0.214CC..  trans-64.7128.7-179.524.8-34.7000111.9D56 C57 L58 F90 D111 A131D56-P88 WeakPolarHBondContact O-CD 3.32Å; D56-P88 WeakPolarHBondContact O-CG 3.43Å; C57-P88 WeakPolarHBondContact CA-O 3.48Å; C57-P88 HydrophobicContact CB-CG 4.13Å; C57-P88 PolarHBondContact SG-O 3.31Å; C57-P88 VanDerWaalsContact SG-O 3.35Å; L58-P88 PolarHBondContact N-O 2.97Å; P88-F90 HydrophobicContact CB-CE2 4.16Å; P88-D111 VanDerWaalsContact CA-OD2 3.28Å; P88-D111 WeakPolarHBondContact CA-OD2 3.4Å; P88-A131 HydrophobicContact CB-CB 3.94Å; P88-A131 HydrophobicContact CG-CB 4.05Å
89V95Very high83.5Confident0 Ų047.7 Ų47.70%023%0.225CC..EExtended strand (participates in β ladder)trans-107.3121.9-179.3-179.60000110.7L58 F60 I77 L80 V87 V110 D111 E112L58-V89 HydrophobicContact CB-CG2 4.42Å; L58-V89 HydrophobicContact CD2-CG1 4.41Å; L58-V89 HydrophobicContact CD2-CG2 4.45Å; L58-V89 CarbonylContact O-C 2.9Å; L58-V89 WeakPolarHBondContact O-CA 3.48Å; F60-V89 HydrophobicContact CD1-CG1 4.08Å; F60-V89 HydrophobicContact CE1-CG1 3.58Å; I77-V89 HydrophobicContact CD1-CG1 4.02Å; I77-V89 HydrophobicContact CG1-CG1 4.26Å; I77-V89 HydrophobicContact CG2-CG2 4.43Å; L80-V89 HydrophobicContact CD2-CG2 3.98Å; V87-V89 PolarHBondContact O-N 3.01Å; V89-V110 HydrophobicContact CG1-CG2 4.29Å; V89-D111 PolarHBondContact N-OD2 2.85Å; V89-D111 PolarHBondContact O-N 2.96Å; V89-E112 PolarHBondContact O-N 2.91Å; V89-E112 VanDerWaalsContact O-N 3.16Å
90F93.5Very high82.1Confident0 Ų050.3 Ų50.30%025%0.254CS..EExtended strand (participates in β ladder)trans-110.9126.6179.4-78.9-118000111C57 L58 M59 F60 P88 E112 A114 R127 A128 A131C57-F90 VanDerWaalsContact SG-CD2 3.56Å; L58-F90 PolarHBondContact O-N 3.26Å; M59-F90 WeakPolarHBondContact CA-O 3.39Å; M59-F90 HydrophobicContact CB-CB 4.4Å; M59-F90 HydrophobicContact CE-CG 4.49Å; M59-F90 HydrophobicContact CG-CB 4.02Å; F60-F90 WeakPolarHBondContact CD1-O 3.25Å; F60-F90 PolarHBondContact N-O 3.45Å; P88-F90 HydrophobicContact CB-CE2 4.16Å; F90-E112 WeakPolarHBondContact CA-O 3.37Å; F90-E112 HydrophobicContact CD1-CB 3.69Å; F90-E112 HydrophobicContact CD2-CB 4.04Å; F90-E112 HydrophobicContact CE1-CB 3.56Å; F90-E112 HydrophobicContact CE1-CG 4.02Å; F90-E112 HydrophobicContact CE2-CB 3.91Å; F90-E112 HydrophobicContact CE2-CG 4.03Å; F90-E112 HydrophobicContact CG-CB 3.93Å; F90-E112 HydrophobicContact CZ-CB 3.67Å; F90-E112 HydrophobicContact CZ-CG 3.7Å; F90-A114 HydrophobicContact CD1-CB 4.34Å; F90-R127 HydrophobicContact CE1-CB 4.38Å; F90-A128 HydrophobicContact CZ-CB 4.34Å; F90-A131 HydrophobicContact CE2-CB 3.88Å; F90-A131 HydrophobicContact CZ-CB 4Å
91L88.8Confident80.7Confident1 Ų151.8 Ų51.81%0.00527%0.266CS..EExtended strand (participates in β ladder)trans-87.9120.9167.217967.8000110.3F60 Y62 M64 A98 M102 V110 E112 F113 A114F60-L91 HydrophobicContact CD2-CD1 3.88Å; F60-L91 HydrophobicContact CE1-CB 4.41Å; F60-L91 HydrophobicContact CE1-CD1 4.35Å; F60-L91 HydrophobicContact CE2-CD1 3.32Å; F60-L91 HydrophobicContact CZ-CB 4.21Å; F60-L91 HydrophobicContact CZ-CD1 3.59Å; F60-L91 HydrophobicContact CZ-CG 4.47Å; Y62-L91 HydrophobicContact CD1-CD1 3.99Å; Y62-L91 HydrophobicContact CE1-CD1 3.71Å; M64-L91 HydrophobicContact CE-CD1 4.19Å; M64-L91 HydrophobicContact CE-CD2 3.7Å; L91-A98 HydrophobicContact CD2-CB 4.33Å; L91-M102 HydrophobicContact CD2-CE 3.89Å; L91-V110 HydrophobicContact CB-CG1 3.96Å; L91-E112 PolarHBondContact N-O 3.33Å; L91-F113 HydrophobicContact CB-CD1 4.02Å; L91-F113 HydrophobicContact CB-CE1 4.09Å; L91-F113 HydrophobicContact CD2-CD1 3.83Å; L91-F113 HydrophobicContact CD2-CE1 3.56Å; L91-F113 HydrophobicContact CG-CD1 4.4Å; L91-F113 HydrophobicContact CG-CE1 4.43Å; L91-A114 PolarHBondContact O-N 3.43Å
92L86.8Confident79.7Confident0 Ų051.9 Ų51.90%027%0.267CS..EExtended strand (participates in β ladder)trans-96.5108.4173.5-52.3-174.3000109.1I6 V22 L25 M59 F60 S61 A114 I116I6-L92 HydrophobicContact CG2-CD1 4.32Å; V22-L92 HydrophobicContact CG2-CD1 4.38Å; L25-L92 HydrophobicContact CD2-CD1 4.04Å; L25-L92 HydrophobicContact CD2-CD2 3.97Å; M59-L92 HydrophobicContact CB-CD1 3.96Å; M59-L92 HydrophobicContact CB-CD2 4.31Å; M59-L92 HydrophobicContact CB-CG 4.08Å; M59-L92 HydrophobicContact SD-CD2 4.34Å; F60-L92 WeakPolarHBondContact O-CB 3.42Å; F60-L92 PolarHBondContact O-N 3.24Å; S61-L92 WeakPolarHBondContact CA-O 3.35Å; S61-L92 WeakPolarHBondContact CB-O 3.4Å; S61-L92 PolarHBondContact OG-O 3.45Å; L92-A114 HydrophobicContact CD2-CB 3.77Å; L92-I116 HydrophobicContact CB-CD1 4.42Å; L92-I116 HydrophobicContact CB-CG2 3.88Å; L92-I116 HydrophobicContact CD2-CG2 3.94Å; L92-I116 HydrophobicContact CG-CG2 4.32Å
93G78.2Confident79Confident9 Ų951.4 Ų51.49%0.09327%0.267CS..EExtended strand (participates in β ladder)trans-153170.9-174.200000115.3A114G93-A114 PolarHBondContact N-O 2.66Å
94D71.4Confident78.7Confident67 Ų6757.3 Ų57.336%0.35829%0.289SS..  trans-82.7135163.5-177.612.4000109.2E96 K97 A98D94-E96 PolarHBondContact O-N 2.95Å; D94-K97 PolarHBondContact O-N 3.43Å; D94-A98 WeakPolarHBondContact O-CB 3.23Å; D94-A98 PolarHBondContact O-N 2.89Å
95R70.4Confident78.2Confident122 Ų12260.4 Ų60.446%0.4631%0.306SS..Hα-helixtrans-59.4-44-170.3-178.1178.6174.2176.7-1.2112.9L99 W115 E118R95-L99 HydrophobicContact CG-CD1 3.87Å; R95-L99 WeakPolarHBondContact O-CB 3.39Å; R95-L99 WeakPolarHBondContact O-CD1 3.34Å; R95-L99 VanDerWaalsContact O-CG 3.3Å; R95-L99 WeakPolarHBondContact O-CG 3.34Å; R95-L99 PolarHBondContact O-N 3.45Å; R95-W115 VanDerWaalsContact CA-CZ3 3.45Å; R95-W115 HydrophobicContact CB-CD2 4.04Å; R95-W115 HydrophobicContact CB-CE3 3.87Å; R95-W115 HydrophobicContact CB-CZ3 4.16Å; R95-W115 HydrophobicContact CG-CD2 4.36Å; R95-W115 HydrophobicContact CG-CE3 4.47Å; R95-W115 HydrophobicContact CG-CH2 4.39Å; R95-W115 HydrophobicContact CG-CZ2 4.25Å; R95-E118 WeakPolarHBondContact CB-OE1 3.22Å; R95-E118 VanDerWaalsContact CD-OE1 3.23Å; R95-E118 WeakPolarHBondContact CD-OE1 3.42Å; R95-E118 IonicContact NH1-OE2 2.65Å
96E66.8Low77.9Confident163 Ų16356.3 Ų56.376%0.76229%0.287SS*.Hα-helixtrans-68.3-43.2-177.4-70.2-169.5165.400111.9D94 A100D94-E96 PolarHBondContact O-N 2.95Å; E96-A100 PolarHBondContact O-N 3.2Å
97K65.7Low77.6Confident95 Ų9555.4 Ų55.441%0.41328%0.282SS..Hα-helixtrans-68.3-44.3178.9-67.9-165.3177.6-166.20111.7E65 D94 A100 A101E65-K97 IonicContact OE1-NZ 3.39Å; E65-K97 PolarHBondContact OE1-NZ 2.59Å; D94-K97 PolarHBondContact O-N 3.43Å; K97-A100 PolarHBondContact O-N 3.27Å; K97-A101 PolarHBondContact O-N 3.12Å
98A64.8Low77.2Confident1 Ų161.5 Ų61.51%0.00831%0.311CS..Hα-helixtrans-58.2-54.2179.800000111.6M64 L91 D94 A100 A101 M102 W115M64-A98 HydrophobicContact CE-CB 4.11Å; M64-A98 VanDerWaalsContact SD-CA 3.58Å; L91-A98 HydrophobicContact CD2-CB 4.33Å; D94-A98 WeakPolarHBondContact O-CB 3.23Å; D94-A98 PolarHBondContact O-N 2.89Å; A98-A100 PolarHBondContact O-N 2.95Å; A98-A100 VanDerWaalsContact O-N 3.14Å; A98-A101 PolarHBondContact O-N 2.78Å; A98-M102 WeakPolarHBondContact O-CG 3.48Å; A98-M102 PolarHBondContact O-N 3.4Å; A98-W115 HydrophobicContact CB-CH2 3.83Å; A98-W115 HydrophobicContact CB-CZ3 3.53Å
99L66.9Low76.7Confident112 Ų11263.2 Ų63.259%0.58632%0.319SS*.Hα-helixtrans-61.1-26.8-176.1-71.5169.6000113.9R95R95-L99 HydrophobicContact CG-CD1 3.87Å; R95-L99 WeakPolarHBondContact O-CB 3.39Å; R95-L99 WeakPolarHBondContact O-CD1 3.34Å; R95-L99 VanDerWaalsContact O-CG 3.3Å; R95-L99 WeakPolarHBondContact O-CG 3.34Å; R95-L99 PolarHBondContact O-N 3.45Å
100A63.4Low76.4Confident91 Ų9163.8 Ų63.875%0.75232%0.322SS*.Hα-helixtrans-80.2-27-17800000113.9E96 K97 A98E96-A100 PolarHBondContact O-N 3.2Å; K97-A100 PolarHBondContact O-N 3.27Å; A98-A100 PolarHBondContact O-N 2.95Å; A98-A100 VanDerWaalsContact O-N 3.14Å
101A62.8Low76.1Confident32 Ų3268.5 Ų68.526%0.26435%0.348SS..Hα-helixtrans-112.11.9-173.200000114.1M64 K97 A98 D103M64-A101 HydrophobicContact CB-CB 4Å; M64-A101 HydrophobicContact CG-CB 4.45Å; M64-A101 HydrophobicContact SD-CB 3.65Å; K97-A101 PolarHBondContact O-N 3.12Å; A98-A101 PolarHBondContact O-N 2.78Å; A101-D103 PolarHBondContact O-N 3.1Å
102M69.3Low76.2Confident37 Ų3771.3 Ų71.318%0.18236%0.361CS..  trans-73.6122.4175.6-51.3-142.778.900111.1L91 A98 L106 L107 F113L91-M102 HydrophobicContact CD2-CE 3.89Å; A98-M102 WeakPolarHBondContact O-CG 3.48Å; A98-M102 PolarHBondContact O-N 3.4Å; M102-L106 HydrophobicContact CE-CD2 3.62Å; M102-L106 HydrophobicContact CE-CG 3.87Å; M102-L107 HydrophobicContact CB-CD1 4.39Å; M102-L107 HydrophobicContact CB-CG 4.27Å; M102-L107 HydrophobicContact CE-CD2 4.08Å; M102-L107 HydrophobicContact CE-CG 4.34Å; M102-L107 HydrophobicContact SD-CD2 3.73Å; M102-L107 HydrophobicContact SD-CG 4.29Å; M102-F113 HydrophobicContact CE-CE1 3.31Å; M102-F113 HydrophobicContact CE-CZ 3.48Å; M102-F113 VanDerWaalsContact CE-CZ 3.48Å; M102-F113 HydrophobicContact SD-CD1 4.29Å; M102-F113 HydrophobicContact SD-CE1 3.23Å; M102-F113 WeakPolarHBondContact SD-CE1 3.46Å; M102-F113 HydrophobicContact SD-CZ 3.4Å; M102-F113 WeakPolarHBondContact SD-CZ 3.5Å
103D75.8Confident76.2Confident65 Ų6573.5 Ų73.535%0.34837%0.371SS..  trans-97.5169.3160.36226.6000111.6R74 A101 D105 L106 L107R74-D103 IonicContact CZ-OD2 3.62Å; R74-D103 IonicContact NH2-OD1 3.24Å; R74-D103 PolarHBondContact NH2-OD1 3.32Å; R74-D103 IonicContact NH2-OD2 3.69Å; R74-D103 PolarHBondContact NH2-OD2 3.27Å; A101-D103 PolarHBondContact O-N 3.1Å; D103-D105 PolarHBondContact O-N 3.01Å; D103-D105 PolarHBondContact OD1-N 3.41Å; D103-L106 PolarHBondContact O-N 3.05Å; D103-L106 PolarHBondContact OD1-N 3.06Å; D103-L107 PolarHBondContact O-N 3.45Å; D103-L107 VanDerWaalsContact O-N 3.16Å
104R82Confident76.5Confident177 Ų17773.1 Ų73.167%0.66837%0.366SS*.Hα-helixtrans-55.3-42.1-179.6177.3-176.5168.7-164.7-9.9111.6L106 L107 E108R104-L106 VanDerWaalsContact C-N 3.34Å; R104-L106 PolarHBondContact O-N 2.77Å; R104-L107 WeakPolarHBondContact O-CB 3.18Å; R104-L107 PolarHBondContact O-N 3.15Å; R104-E108 IonicContact CZ-OE1 2.66Å; R104-E108 VanDerWaalsContact CZ-OE1 3.3Å; R104-E108 IonicContact NE-OE1 2.71Å; R104-E108 PolarHBondContact NE-OE1 3.26Å; R104-E108 IonicContact NH2-OE1 3.04Å; R104-E108 PolarHBondContact NH2-OE1 2.94Å; R104-E108 PolarHBondContact O-N 3.19Å
105D79.3Confident77.2Confident89 Ų8972.1 Ų72.148%0.47636%0.357SS..Hα-helixtrans-65.6-40-174.7-60.2-14.9000110.8D103 E108 L109D103-D105 PolarHBondContact O-N 3.01Å; D103-D105 PolarHBondContact OD1-N 3.41Å; D105-E108 PolarHBondContact O-N 3.46Å; D105-L109 WeakPolarHBondContact O-CG 3.43Å
106L79.1Confident77.9Confident4 Ų466.8 Ų66.82%0.02134%0.338CS..Hα-helixtrans-67.9-37.6174.4-17563.5000112.3F60 Y62 V73 M102 D103 R104 E108 L109 V110F60-L106 HydrophobicContact CZ-CD1 4.45Å; Y62-L106 VanDerWaalsContact OH-CD2 3.28Å; Y62-L106 WeakPolarHBondContact OH-CD2 3.23Å; V73-L106 HydrophobicContact CG1-CD1 3.79Å; M102-L106 HydrophobicContact CE-CD2 3.62Å; M102-L106 HydrophobicContact CE-CG 3.87Å; D103-L106 PolarHBondContact O-N 3.05Å; D103-L106 PolarHBondContact OD1-N 3.06Å; R104-L106 VanDerWaalsContact C-N 3.34Å; R104-L106 PolarHBondContact O-N 2.77Å; L106-E108 VanDerWaalsContact C-N 3.28Å; L106-E108 PolarHBondContact O-N 2.9Å; L106-L109 PolarHBondContact O-N 2.91Å; L106-L109 VanDerWaalsContact O-N 3.11Å; L106-V110 HydrophobicContact CD1-CG2 4.07Å; L106-V110 HydrophobicContact CG-CG2 4.31Å; L106-V110 WeakPolarHBondContact O-CG2 3.44Å; L106-V110 PolarHBondContact O-N 2.82Å
107L81.5Confident78.6Confident88 Ų8862.4 Ų62.446%0.46132%0.32SS..Hα-helixtrans-64.7-30.5177.3-76.7165.2000113.1M102 D103 R104 L109 F113M102-L107 HydrophobicContact CB-CD1 4.39Å; M102-L107 HydrophobicContact CB-CG 4.27Å; M102-L107 HydrophobicContact CE-CD2 4.08Å; M102-L107 HydrophobicContact CE-CG 4.34Å; M102-L107 HydrophobicContact SD-CD2 3.73Å; M102-L107 HydrophobicContact SD-CG 4.29Å; D103-L107 PolarHBondContact O-N 3.45Å; D103-L107 VanDerWaalsContact O-N 3.16Å; R104-L107 WeakPolarHBondContact O-CB 3.18Å; R104-L107 PolarHBondContact O-N 3.15Å; L107-L109 VanDerWaalsContact C-N 3.26Å; L107-F113 HydrophobicContact CD2-CE2 4.06Å; L107-F113 HydrophobicContact CD2-CZ 3.68Å
108E85.2Confident79.6Confident127 Ų12763 Ų6359%0.59332%0.324SS*.Hα-helixtrans-75.2-16.6174.7-71.1-179.3-172.100112.5R104 D105 L106R104-E108 IonicContact CZ-OE1 2.66Å; R104-E108 VanDerWaalsContact CZ-OE1 3.3Å; R104-E108 IonicContact NE-OE1 2.71Å; R104-E108 PolarHBondContact NE-OE1 3.26Å; R104-E108 IonicContact NH2-OE1 3.04Å; R104-E108 PolarHBondContact NH2-OE1 2.94Å; R104-E108 PolarHBondContact O-N 3.19Å; D105-E108 PolarHBondContact O-N 3.46Å; L106-E108 VanDerWaalsContact C-N 3.28Å; L106-E108 PolarHBondContact O-N 2.9Å
109L84.6Confident80.7Confident48 Ų4865.3 Ų65.325%0.25134%0.336SS..Hα-helixtrans-99.8-14-178-69.3176.9000114.4R74 I77 D105 L106 L107R74-L109 HydrophobicContact CG-CD1 4.3Å; I77-L109 HydrophobicContact CD1-CB 4.03Å; I77-L109 HydrophobicContact CG2-CB 4.13Å; I77-L109 HydrophobicContact CG2-CD2 4.02Å; I77-L109 HydrophobicContact CG2-CG 4.46Å; D105-L109 WeakPolarHBondContact O-CG 3.43Å; L106-L109 PolarHBondContact O-N 2.91Å; L106-L109 VanDerWaalsContact O-N 3.11Å; L107-L109 VanDerWaalsContact C-N 3.26Å
110V87.2Confident81.8Confident11 Ų1164.3 Ų64.37%0.06733%0.334CS..  trans-111.3123.8-176.91760000109.5F60 V89 L91 L106 E112 F113F60-V110 HydrophobicContact CE1-CG2 4.1Å; F60-V110 HydrophobicContact CZ-CG2 3.94Å; V89-V110 HydrophobicContact CG1-CG2 4.29Å; L91-V110 HydrophobicContact CB-CG1 3.96Å; L106-V110 HydrophobicContact CD1-CG2 4.07Å; L106-V110 HydrophobicContact CG-CG2 4.31Å; L106-V110 WeakPolarHBondContact O-CG2 3.44Å; L106-V110 PolarHBondContact O-N 2.82Å; V110-E112 VanDerWaalsContact CG1-O 3.27Å; V110-E112 WeakPolarHBondContact CG1-O 2.99Å; V110-F113 HydrophobicContact CB-CZ 4.42Å; V110-F113 HydrophobicContact CG1-CE1 4.19Å; V110-F113 HydrophobicContact CG1-CE2 4.39Å; V110-F113 HydrophobicContact CG1-CZ 4.02Å
111D89.3Confident83.2Confident100 Ų10061.1 Ų61.154%0.53531%0.308SS..SBendtrans-80-36.3178.8-61.7-79000112.5P88 V89P88-D111 VanDerWaalsContact CA-OD2 3.28Å; P88-D111 WeakPolarHBondContact CA-OD2 3.4Å; V89-D111 PolarHBondContact N-OD2 2.85Å; V89-D111 PolarHBondContact O-N 2.96Å
112E89Confident84.7Confident60 Ų6064.2 Ų64.228%0.2832%0.321SS..EExtended strand (participates in β ladder)trans-143.8147-170.8-71.4-76.5-167.100113.1V89 F90 L91 V110 R127V89-E112 PolarHBondContact O-N 2.91Å; V89-E112 VanDerWaalsContact O-N 3.16Å; F90-E112 WeakPolarHBondContact CA-O 3.37Å; F90-E112 HydrophobicContact CD1-CB 3.69Å; F90-E112 HydrophobicContact CD2-CB 4.04Å; F90-E112 HydrophobicContact CE1-CB 3.56Å; F90-E112 HydrophobicContact CE1-CG 4.02Å; F90-E112 HydrophobicContact CE2-CB 3.91Å; F90-E112 HydrophobicContact CE2-CG 4.03Å; F90-E112 HydrophobicContact CG-CB 3.93Å; F90-E112 HydrophobicContact CZ-CB 3.67Å; F90-E112 HydrophobicContact CZ-CG 3.7Å; L91-E112 PolarHBondContact N-O 3.33Å; V110-E112 VanDerWaalsContact CG1-O 3.27Å; V110-E112 WeakPolarHBondContact CG1-O 2.99Å; E112-R127 IonicContact OE2-CZ 3.81Å; E112-R127 IonicContact OE2-NH2 2.72Å; E112-R127 PolarHBondContact OE2-NH2 3.2Å
113F86.6Confident85.8Confident46 Ų4667.8 Ų67.820%0.20234%0.335CS..EExtended strand (participates in β ladder)trans-106.7131.2171.9-64.7-83.8000110.4L91 M102 L107 V110 W115 R127L91-F113 HydrophobicContact CB-CD1 4.02Å; L91-F113 HydrophobicContact CB-CE1 4.09Å; L91-F113 HydrophobicContact CD2-CD1 3.83Å; L91-F113 HydrophobicContact CD2-CE1 3.56Å; L91-F113 HydrophobicContact CG-CD1 4.4Å; L91-F113 HydrophobicContact CG-CE1 4.43Å; M102-F113 HydrophobicContact CE-CE1 3.31Å; M102-F113 HydrophobicContact CE-CZ 3.48Å; M102-F113 VanDerWaalsContact CE-CZ 3.48Å; M102-F113 HydrophobicContact SD-CD1 4.29Å; M102-F113 HydrophobicContact SD-CE1 3.23Å; M102-F113 WeakPolarHBondContact SD-CE1 3.46Å; M102-F113 HydrophobicContact SD-CZ 3.4Å; M102-F113 WeakPolarHBondContact SD-CZ 3.5Å; L107-F113 HydrophobicContact CD2-CE2 4.06Å; L107-F113 HydrophobicContact CD2-CZ 3.68Å; V110-F113 HydrophobicContact CB-CZ 4.42Å; V110-F113 HydrophobicContact CG1-CE1 4.19Å; V110-F113 HydrophobicContact CG1-CE2 4.39Å; V110-F113 HydrophobicContact CG1-CZ 4.02Å; F113-W115 HydrophobicContact CB-CH2 4.22Å; F113-W115 HydrophobicContact CB-CZ2 3.94Å; F113-W115 HydrophobicContact CD1-CH2 4.11Å; F113-W115 HydrophobicContact CG-CH2 4.37Å; F113-W115 HydrophobicContact CG-CZ2 4.36Å; F113-R127 PolarHBondContact O-NH1 2.96Å; F113-R127 PolarHBondContact O-NH2 3.48Å
114A86.3Confident86.6Confident0 Ų064.8 Ų64.80%032%0.319CS..EExtended strand (participates in β ladder)trans-121.9112173.900000110.3F90 L91 L92 G93 I116 I124F90-A114 HydrophobicContact CD1-CB 4.34Å; L91-A114 PolarHBondContact O-N 3.43Å; L92-A114 HydrophobicContact CD2-CB 3.77Å; G93-A114 PolarHBondContact N-O 2.66Å; A114-I116 PolarHBondContact O-N 2.98Å; A114-I116 VanDerWaalsContact O-N 3.09Å; A114-I124 HydrophobicContact CB-CD1 4.25Å; A114-I124 HydrophobicContact CB-CG1 4.25Å; A114-I124 HydrophobicContact CB-CG2 3.67Å
115W85Confident87.3Confident46 Ų4656.3 Ų56.317%0.17429%0.287CS..EExtended strand (participates in β ladder)trans-83.384.6178.7-52122.8000109.1R95 A98 F113 L117 E118 D119R95-W115 VanDerWaalsContact CA-CZ3 3.45Å; R95-W115 HydrophobicContact CB-CD2 4.04Å; R95-W115 HydrophobicContact CB-CE3 3.87Å; R95-W115 HydrophobicContact CB-CZ3 4.16Å; R95-W115 HydrophobicContact CG-CD2 4.36Å; R95-W115 HydrophobicContact CG-CE3 4.47Å; R95-W115 HydrophobicContact CG-CH2 4.39Å; R95-W115 HydrophobicContact CG-CZ2 4.25Å; A98-W115 HydrophobicContact CB-CH2 3.83Å; A98-W115 HydrophobicContact CB-CZ3 3.53Å; F113-W115 HydrophobicContact CB-CH2 4.22Å; F113-W115 HydrophobicContact CB-CZ2 3.94Å; F113-W115 HydrophobicContact CD1-CH2 4.11Å; F113-W115 HydrophobicContact CG-CH2 4.37Å; F113-W115 HydrophobicContact CG-CZ2 4.36Å; W115-L117 PolarHBondContact O-N 2.88Å; W115-E118 HydrophobicContact CB-CB 3.88Å; W115-E118 HydrophobicContact CB-CG 4.22Å; W115-E118 PolarHBondContact O-N 3.32Å; W115-D119 PolarHBondContact O-N 3.46Å
116I84.7Confident88Confident10 Ų1053.8 Ų53.85%0.05128%0.282CS..THydrogen-bonded Turntrans-60.4-13.2-170.656.2174.2000115V18 A21 V22 L92 A114 I124V18-I116 HydrophobicContact CG1-CD1 3.38Å; V18-I116 HydrophobicContact CG1-CG1 4.49Å; A21-I116 HydrophobicContact CB-CB 4.28Å; A21-I116 HydrophobicContact CB-CD1 4.49Å; V22-I116 HydrophobicContact CG2-CD1 4.15Å; L92-I116 HydrophobicContact CB-CD1 4.42Å; L92-I116 HydrophobicContact CB-CG2 3.88Å; L92-I116 HydrophobicContact CD2-CG2 3.94Å; L92-I116 HydrophobicContact CG-CG2 4.32Å; A114-I116 PolarHBondContact O-N 2.98Å; A114-I116 VanDerWaalsContact O-N 3.09Å; I116-I124 HydrophobicContact CG2-CD1 4.15Å
117L83.1Confident88.8Confident72 Ų7256.4 Ų56.438%0.37729%0.291SS..THydrogen-bonded Turntrans-101.7-20.1175.5-57-172.7000113.9W17 V18 A21 W115W17-L117 VanDerWaalsContact CD1-CD2 3.49Å; V18-L117 HydrophobicContact CG2-CD1 4.39Å; A21-L117 HydrophobicContact CB-CD2 4.15Å; W115-L117 PolarHBondContact O-N 2.88Å
118E85Confident89.4Confident107 Ų10752.2 Ų52.250%0.527%0.269SS..THydrogen-bonded Turntrans-99.6-40.4-179-61.9-175.4-164.900111.7R95 W115R95-E118 WeakPolarHBondContact CB-OE1 3.22Å; R95-E118 VanDerWaalsContact CD-OE1 3.23Å; R95-E118 WeakPolarHBondContact CD-OE1 3.42Å; R95-E118 IonicContact NH1-OE2 2.65Å; W115-E118 HydrophobicContact CB-CB 3.88Å; W115-E118 HydrophobicContact CB-CG 4.22Å; W115-E118 PolarHBondContact O-N 3.32Å
119D87.9Confident89.9Confident50 Ų5047.4 Ų47.427%0.26725%0.249SC..SBendtrans-90.4152.9-179.8-72.3-31.3000111.7W115 F123 I124 R127W115-D119 PolarHBondContact O-N 3.46Å; D119-F123 HydrophobicContact CB-CD1 4.47Å; D119-I124 HydrophobicContact CB-CD1 3.87Å; D119-I124 HydrophobicContact CB-CG1 3.73Å; D119-R127 IonicContact OD2-NH1 3.8Å
120T91.4Very high90.4Very high90 Ų9047.2 Ų47.255%0.55225%0.254SS*.  trans-74.7144.3173.966.30000110.9D122 F123 I124T120-D122 PolarHBondContact O-N 3.43Å; T120-F123 PolarHBondContact O-N 3.17Å; T120-F123 VanDerWaalsContact O-N 3.07Å; T120-F123 VanDerWaalsContact OG1-CB 3.26Å; T120-F123 WeakPolarHBondContact OG1-CB 3.2Å; T120-F123 PolarHBondContact OG1-N 3.4Å; T120-I124 WeakPolarHBondContact O-CG1 3.36Å; T120-I124 PolarHBondContact O-N 2.98Å
121A92Very high90.8Very high25 Ų2547 Ų4721%0.20725%0.253CS..Hα-helixtrans-54.5-39.3176.100000112.7R24 A28 I124 A125R24-A121 HydrophobicContact CB-CB 4.05Å; A28-A121 HydrophobicContact CB-CB 4.16Å; A121-I124 PolarHBondContact O-N 3.42Å; A121-A125 VanDerWaalsContact O-CB 3.28Å; A121-A125 WeakPolarHBondContact O-CB 3.5Å; A121-A125 PolarHBondContact O-N 3.45Å
122D93.4Very high91.1Very high97 Ų9742.2 Ų42.252%0.51923%0.228SC..Hα-helixtrans-62.2-43.2176.2-17863.7000112.5T120 A125 G126T120-D122 PolarHBondContact O-N 3.43Å; D122-A125 PolarHBondContact O-N 3.04Å; D122-G126 PolarHBondContact O-N 3.21Å
123F94Very high91.2Very high111 Ų11142 Ų4249%0.48723%0.231SC..Hα-helixtrans-68-43.2178.7-177.7-113.2000112.2D119 T120 G126 R127D119-F123 HydrophobicContact CB-CD1 4.47Å; T120-F123 PolarHBondContact O-N 3.17Å; T120-F123 VanDerWaalsContact O-N 3.07Å; T120-F123 VanDerWaalsContact OG1-CB 3.26Å; T120-F123 WeakPolarHBondContact OG1-CB 3.2Å; T120-F123 PolarHBondContact OG1-N 3.4Å; F123-G126 PolarHBondContact O-N 3.11Å; F123-R127 HydrophobicContact CE1-CG 4.28Å; F123-R127 HydrophobicContact CZ-CG 4.22Å; F123-R127 WeakPolarHBondContact O-CG 3.42Å; F123-R127 PolarHBondContact O-N 2.9Å
124I93Very high91.5Very high2 Ų245.9 Ų45.91%0.0124%0.244CC..Hα-helixtrans-61.7-45.4175.5-60.6168000110.1L25 A114 I116 D119 T120 A121 G126 R127 A128L25-I124 HydrophobicContact CD1-CB 3.83Å; L25-I124 HydrophobicContact CD1-CG2 3.63Å; L25-I124 HydrophobicContact CD2-CG2 3.9Å; L25-I124 HydrophobicContact CG-CG2 4.45Å; A114-I124 HydrophobicContact CB-CD1 4.25Å; A114-I124 HydrophobicContact CB-CG1 4.25Å; A114-I124 HydrophobicContact CB-CG2 3.67Å; I116-I124 HydrophobicContact CG2-CD1 4.15Å; D119-I124 HydrophobicContact CB-CD1 3.87Å; D119-I124 HydrophobicContact CB-CG1 3.73Å; T120-I124 WeakPolarHBondContact O-CG1 3.36Å; T120-I124 PolarHBondContact O-N 2.98Å; A121-I124 PolarHBondContact O-N 3.42Å; I124-G126 VanDerWaalsContact C-N 3.33Å; I124-G126 PolarHBondContact O-N 2.86Å; I124-R127 WeakPolarHBondContact O-CB 3.38Å; I124-R127 PolarHBondContact O-N 2.91Å; I124-A128 PolarHBondContact O-N 3.12Å
125A94.8Very high91.7Very high0 Ų046.9 Ų46.90%025%0.248CC..Hα-helixtrans-58.8-44.1175.600000111.6L25 A28 L29 A121 D122 R127 A128 V129L25-A125 HydrophobicContact CD1-CB 4.15Å; A28-A125 HydrophobicContact CB-CB 3.83Å; L29-A125 HydrophobicContact CD2-CB 3.99Å; L29-A125 HydrophobicContact CG-CB 3.99Å; A121-A125 VanDerWaalsContact O-CB 3.28Å; A121-A125 WeakPolarHBondContact O-CB 3.5Å; A121-A125 PolarHBondContact O-N 3.45Å; D122-A125 PolarHBondContact O-N 3.04Å; A125-R127 PolarHBondContact O-N 3.42Å; A125-A128 PolarHBondContact O-N 3.45Å; A125-V129 WeakPolarHBondContact O-CG2 3.3Å; A125-V129 PolarHBondContact O-N 3.06Å
126G95.1Very high91.9Very high35 Ų3548.9 Ų48.936%0.36126%0.255SS..Hα-helixtrans-60.6-40.6175.200000113.5D122 F123 I124 V129 A130D122-G126 PolarHBondContact O-N 3.21Å; F123-G126 PolarHBondContact O-N 3.11Å; I124-G126 VanDerWaalsContact C-N 3.33Å; I124-G126 PolarHBondContact O-N 2.86Å; G126-V129 PolarHBondContact O-N 2.99Å; G126-A130 PolarHBondContact O-N 3.48Å
127R95Very high91.8Very high59 Ų5954.6 Ų54.622%0.22328%0.282CS..Hα-helixtrans-63.2-44.7174.1-74.4175.963.8-158.6-2.4111.8F90 E112 F113 D119 F123 I124 A125 A130 A131F90-R127 HydrophobicContact CE1-CB 4.38Å; E112-R127 IonicContact OE2-CZ 3.81Å; E112-R127 IonicContact OE2-NH2 2.72Å; E112-R127 PolarHBondContact OE2-NH2 3.2Å; F113-R127 PolarHBondContact O-NH1 2.96Å; F113-R127 PolarHBondContact O-NH2 3.48Å; D119-R127 IonicContact OD2-NH1 3.8Å; F123-R127 HydrophobicContact CE1-CG 4.28Å; F123-R127 HydrophobicContact CZ-CG 4.22Å; F123-R127 WeakPolarHBondContact O-CG 3.42Å; F123-R127 PolarHBondContact O-N 2.9Å; I124-R127 WeakPolarHBondContact O-CB 3.38Å; I124-R127 PolarHBondContact O-N 2.91Å; A125-R127 PolarHBondContact O-N 3.42Å; R127-A130 WeakPolarHBondContact O-CB 3.44Å; R127-A130 PolarHBondContact O-N 3.02Å; R127-A131 PolarHBondContact O-N 3.47Å
128A95.1Very high91.9Very high0 Ų058.4 Ų58.40%030%0.298CS..Hα-helixtrans-61.4-45.4176.800000111.5L29 M59 F90 I124 A125 A130 A131 M132L29-A128 HydrophobicContact CD2-CB 4.12Å; M59-A128 HydrophobicContact CE-CB 3.21Å; F90-A128 HydrophobicContact CZ-CB 4.34Å; I124-A128 PolarHBondContact O-N 3.12Å; A125-A128 PolarHBondContact O-N 3.45Å; A128-A130 VanDerWaalsContact C-N 3.31Å; A128-A130 PolarHBondContact O-N 3.48Å; A128-A131 PolarHBondContact O-N 2.82Å; A128-A131 VanDerWaalsContact O-N 3.15Å; A128-M132 VanDerWaalsContact C-CE 3.48Å; A128-M132 HydrophobicContact CB-CE 3.94Å; A128-M132 WeakPolarHBondContact O-CB 3.39Å; A128-M132 WeakPolarHBondContact O-CE 3.27Å; A128-M132 VanDerWaalsContact O-CG 3.29Å; A128-M132 WeakPolarHBondContact O-CG 3.3Å; A128-M132 PolarHBondContact O-N 2.9Å
129V95.9Very high92Very high27 Ų2756.8 Ų56.816%0.16429%0.292CS..Hα-helixtrans-59.7-40.5175.4171.50000111.8M2 Q32 V34 A125 G126 M132 T133M2-V129 HydrophobicContact CE-CG1 4.21Å; Q32-V129 HydrophobicContact CB-CG2 4.12Å; V34-V129 HydrophobicContact CG2-CG2 3.84Å; A125-V129 WeakPolarHBondContact O-CG2 3.3Å; A125-V129 PolarHBondContact O-N 3.06Å; G126-V129 PolarHBondContact O-N 2.99Å; V129-M132 HydrophobicContact CG2-CE 4Å; V129-T133 WeakPolarHBondContact O-CB 3.36Å; V129-T133 PolarHBondContact O-N 3.43Å; V129-T133 PolarHBondContact O-OG1 2.88Å
130A94.8Very high92.1Very high43 Ų4357.2 Ų57.236%0.35529%0.294SS..Hα-helixtrans-63.5-42.417500000112.1G126 R127 A128 T133 R134G126-A130 PolarHBondContact O-N 3.48Å; R127-A130 WeakPolarHBondContact O-CB 3.44Å; R127-A130 PolarHBondContact O-N 3.02Å; A128-A130 VanDerWaalsContact C-N 3.31Å; A128-A130 PolarHBondContact O-N 3.48Å; A130-T133 PolarHBondContact O-N 2.72Å; A130-R134 WeakPolarHBondContact O-CG 3.4Å; A130-R134 PolarHBondContact O-N 3.39Å; A130-R134 VanDerWaalsContact O-N 3.11Å
131A95.1Very high92.2Very high6 Ų653.3 Ų53.35%0.0527%0.27CS..Hα-helixtrans-65.1-48.1176.400000112.1P88 F90 R127 A128 T133 R134 Y135P88-A131 HydrophobicContact CB-CB 3.94Å; P88-A131 HydrophobicContact CG-CB 4.05Å; F90-A131 HydrophobicContact CE2-CB 3.88Å; F90-A131 HydrophobicContact CZ-CB 4Å; R127-A131 PolarHBondContact O-N 3.47Å; A128-A131 PolarHBondContact O-N 2.82Å; A128-A131 VanDerWaalsContact O-N 3.15Å; A131-T133 VanDerWaalsContact C-N 3.26Å; A131-T133 PolarHBondContact O-N 3.39Å; A131-R134 PolarHBondContact O-N 2.92Å; A131-R134 VanDerWaalsContact O-N 3.12Å; A131-Y135 PolarHBondContact O-N 3.27Å
132M94.9Very high92.4Very high0 Ų054.2 Ų54.20%027%0.274CS..Hα-helixtrans-56-40.9174.8-71.2-173.7-92.700111.7M2 L29 V34 D56 C57 A128 V129 Y135 R136M2-M132 HydrophobicContact CB-SD 4.01Å; M2-M132 HydrophobicContact CG-CB 4.41Å; M2-M132 HydrophobicContact CG-SD 4.43Å; M2-M132 HydrophobicContact SD-CB 3.54Å; M2-M132 VanDerWaalsContact SD-CB 3.54Å; M2-M132 HydrophobicContact SD-CG 4.47Å; M2-M132 HydrophobicContact SD-SD 4.26Å; L29-M132 HydrophobicContact CD2-CE 4.16Å; V34-M132 HydrophobicContact CG1-CE 3.99Å; V34-M132 HydrophobicContact CG1-SD 4.14Å; V34-M132 HydrophobicContact CG2-CE 3.93Å; D56-M132 HydrophobicContact CB-CB 4Å; D56-M132 HydrophobicContact CB-CG 3.67Å; D56-M132 HydrophobicContact CB-SD 3.81Å; D56-M132 WeakPolarHBondContact O-CG 3.49Å; C57-M132 HydrophobicContact CB-CG 3.65Å; C57-M132 HydrophobicContact CB-SD 3.98Å; A128-M132 VanDerWaalsContact C-CE 3.48Å; A128-M132 HydrophobicContact CB-CE 3.94Å; A128-M132 WeakPolarHBondContact O-CB 3.39Å; A128-M132 WeakPolarHBondContact O-CE 3.27Å; A128-M132 VanDerWaalsContact O-CG 3.29Å; A128-M132 WeakPolarHBondContact O-CG 3.3Å; A128-M132 PolarHBondContact O-N 2.9Å; V129-M132 HydrophobicContact CG2-CE 4Å; M132-Y135 PolarHBondContact O-N 2.91Å; M132-R136 WeakPolarHBondContact O-CG 3.31Å; M132-R136 PolarHBondContact O-N 3.26Å
133T91.9Very high92.5Very high56 Ų5649.6 Ų49.634%0.34425%0.249SC..Hα-helixtrans-64.7-43177.5-59.30000111.7V129 A130 A131 R136 Q137V129-T133 WeakPolarHBondContact O-CB 3.36Å; V129-T133 PolarHBondContact O-N 3.43Å; V129-T133 PolarHBondContact O-OG1 2.88Å; A130-T133 PolarHBondContact O-N 2.72Å; A131-T133 VanDerWaalsContact C-N 3.26Å; A131-T133 PolarHBondContact O-N 3.39Å; T133-R136 PolarHBondContact O-N 3.25Å; T133-Q137 VanDerWaalsContact O-CG 3.31Å; T133-Q137 WeakPolarHBondContact O-CG 3.24Å; T133-Q137 PolarHBondContact O-N 2.97Å; T133-Q137 VanDerWaalsContact O-N 3.16Å
134R92.2Very high92.5Very high127 Ų12747.5 Ų47.548%0.47924%0.24SC..Hα-helixtrans-64-43.9175.9-71.1-174.4-62.4-113.47.2111.7A130 A131 R136 Q137 Q138A130-R134 WeakPolarHBondContact O-CG 3.4Å; A130-R134 PolarHBondContact O-N 3.39Å; A130-R134 VanDerWaalsContact O-N 3.11Å; A131-R134 PolarHBondContact O-N 2.92Å; A131-R134 VanDerWaalsContact O-N 3.12Å; R134-R136 PolarHBondContact O-N 3.48Å; R134-Q137 WeakPolarHBondContact O-CB 3.25Å; R134-Q137 PolarHBondContact O-N 3.23Å; R134-Q138 PolarHBondContact O-N 3.24Å
135Y92.2Very high92.5Very high21 Ų2148.2 Ų48.28%0.08225%0.245CC..Hα-helixtrans-56.7-50.8175.9167.9-118.9000111.3D56 N86 V87 A131 M132 Q137 Q138 L139D56-Y135 HydrophobicContact CB-CD1 4.37Å; N86-Y135 HydrophobicContact CB-CD2 4.26Å; N86-Y135 HydrophobicContact CB-CE2 4.24Å; N86-Y135 WeakPolarHBondContact O-CD2 3.31Å; V87-Y135 HydrophobicContact CG2-CE1 3.76Å; V87-Y135 HydrophobicContact CG2-CE2 3.95Å; V87-Y135 VanDerWaalsContact CG2-CZ 3.42Å; V87-Y135 WeakPolarHBondContact CG2-OH 3.45Å; A131-Y135 PolarHBondContact O-N 3.27Å; M132-Y135 PolarHBondContact O-N 2.91Å; Y135-Q137 VanDerWaalsContact C-N 3.26Å; Y135-Q137 PolarHBondContact O-N 2.99Å; Y135-Q138 CarbonylContact O-C 3.5Å; Y135-Q138 PolarHBondContact O-N 3.19Å; Y135-L139 HydrophobicContact CE1-CD2 4.1Å; Y135-L139 HydrophobicContact CE2-CB 4.49Å; Y135-L139 HydrophobicContact CE2-CD1 4.18Å; Y135-L139 WeakPolarHBondContact O-CB 3.39Å; Y135-L139 PolarHBondContact O-N 2.71Å
136R87.8Confident92.4Very high88 Ų8849.2 Ų49.233%0.33225%0.253SS..Hα-helixtrans-59.5-32.6177.8-76-179.8168.6-153.6-9.3114.3M1 M2 D56 M132 T133 R134 Q138M1-R136 PolarHBondContact O-NH2 3.17Å; M2-R136 VanDerWaalsContact CA-NH2 3.35Å; D56-R136 VanDerWaalsContact CG-NH2 3.32Å; D56-R136 IonicContact OD1-CZ 3.94Å; D56-R136 IonicContact OD1-NE 3.93Å; D56-R136 PolarHBondContact OD1-NE 3.49Å; D56-R136 IonicContact OD1-NH2 2.83Å; D56-R136 PolarHBondContact OD1-NH2 2.91Å; D56-R136 VanDerWaalsContact OD1-NH2 3.15Å; D56-R136 IonicContact OD2-CZ 3.32Å; D56-R136 IonicContact OD2-NE 2.97Å; D56-R136 IonicContact OD2-NH2 3.53Å; D56-R136 PolarHBondContact OD2-NH2 3.07Å; M132-R136 WeakPolarHBondContact O-CG 3.31Å; M132-R136 PolarHBondContact O-N 3.26Å; T133-R136 PolarHBondContact O-N 3.25Å; R134-R136 PolarHBondContact O-N 3.48Å; R136-Q138 PolarHBondContact O-N 2.84Å
137Q84.2Confident92.2Very high130 Ų13047.7 Ų47.761%0.60724%0.237SC*.Hα-helixtrans-67.1-24.5176.4-73.6171.40.100112.9T133 R134 Y135T133-Q137 VanDerWaalsContact O-CG 3.31Å; T133-Q137 WeakPolarHBondContact O-CG 3.24Å; T133-Q137 PolarHBondContact O-N 2.97Å; T133-Q137 VanDerWaalsContact O-N 3.16Å; R134-Q137 WeakPolarHBondContact O-CB 3.25Å; R134-Q137 PolarHBondContact O-N 3.23Å; Y135-Q137 VanDerWaalsContact C-N 3.26Å; Y135-Q137 PolarHBondContact O-N 2.99Å
138Q84.4Confident91.9Very high152 Ų15248.6 Ų48.671%0.7125%0.245SC*.Hα-helixtrans-100.4-20.8179.2-62.9178.1-2.900112.9R134 Y135 R136R134-Q138 PolarHBondContact O-N 3.24Å; Y135-Q138 CarbonylContact O-C 3.5Å; Y135-Q138 PolarHBondContact O-N 3.19Å; R136-Q138 PolarHBondContact O-N 2.84Å
139L86.5Confident91.5Very high74 Ų7454.8 Ų54.839%0.38727%0.272SS..Hα-helixtrans-66.2-42.5-176.9179.562.8000113.1Y135Y135-L139 HydrophobicContact CE1-CD2 4.1Å; Y135-L139 HydrophobicContact CE2-CB 4.49Å; Y135-L139 HydrophobicContact CE2-CD1 4.18Å; Y135-L139 WeakPolarHBondContact O-CB 3.39Å; Y135-L139 PolarHBondContact O-N 2.71Å
140L90.2Very high91Very high59 Ų5954.7 Ų54.731%0.30927%0.269SS..SBendtrans-83.1135.3-172.9-61.5-179.2000111F144 M148L140-F144 HydrophobicContact CD2-CD1 3.98Å; L140-F144 HydrophobicContact CD2-CE1 4.1Å; L140-M148 HydrophobicContact CD1-SD 3.57Å; L140-M148 VanDerWaalsContact CD1-SD 3.57Å
141P94.7Very high90.6Very high7 Ų753.5 Ų53.55%0.04526%0.258CS..  trans-70.8162.6178.632.7-37.2000111.8L143 F144 S145 Y214 D433 V434P141-L143 PolarHBondContact O-N 3.41Å; P141-F144 HydrophobicContact CG-CB 4.08Å; P141-F144 PolarHBondContact O-N 3.47Å; P141-S145 WeakPolarHBondContact O-CB 3.42Å; P141-S145 PolarHBondContact O-N 2.79Å; P141-Y214 HydrophobicContact CB-CD1 4.28Å; P141-Y214 HydrophobicContact CB-CE1 4Å; P141-D433 VanDerWaalsContact C-OD2 3.31Å; P141-D433 VanDerWaalsContact CB-CG 3.47Å; P141-D433 VanDerWaalsContact CB-OD2 3.25Å; P141-D433 WeakPolarHBondContact CB-OD2 3.38Å; P141-D433 HydrophobicContact CG-CB 4.32Å; P141-D433 VanDerWaalsContact CG-OD2 3.27Å; P141-D433 WeakPolarHBondContact CG-OD2 3.4Å; P141-V434 HydrophobicContact CG-CG2 4.19Å
142P94.9Very high90.1Very high45 Ų4558.5 Ų58.529%0.29228%0.284SS..Hα-helixtrans-55.6-44.8-163.3-27.835.3000114.7A146 E210P142-A146 WeakPolarHBondContact O-CB 3.5Å; P142-A146 PolarHBondContact O-N 2.97Å; P142-E210 HydrophobicContact CB-CB 3.88Å; P142-E210 HydrophobicContact CG-CB 4.28Å
143L95.2Very high89.5Confident0 Ų062.7 Ų62.70%031%0.305CS..Hα-helixtrans-75.3-47.1-176.7175.664.8000111P141 S145 A146 L147 A207 F208 C429 D433P141-L143 PolarHBondContact O-N 3.41Å; L143-S145 PolarHBondContact O-N 3.31Å; L143-A146 PolarHBondContact O-N 2.8Å; L143-A146 VanDerWaalsContact O-N 3.17Å; L143-L147 HydrophobicContact CD1-CD1 4.27Å; L143-L147 HydrophobicContact CD1-CG 4.27Å; L143-L147 HydrophobicContact CG-CD1 4.07Å; L143-L147 HydrophobicContact CG-CG 4.49Å; L143-L147 WeakPolarHBondContact O-CG 3.27Å; L143-L147 PolarHBondContact O-N 3.11Å; L143-A207 HydrophobicContact CD1-CB 4.09Å; L143-F208 HydrophobicContact CD1-CD1 4.09Å; L143-F208 HydrophobicContact CD1-CD2 4.08Å; L143-F208 HydrophobicContact CD1-CE1 3.91Å; L143-F208 HydrophobicContact CD1-CE2 3.9Å; L143-F208 HydrophobicContact CD1-CG 4.18Å; L143-F208 HydrophobicContact CD1-CZ 3.8Å; L143-F208 HydrophobicContact CD2-CD1 3.84Å; L143-F208 HydrophobicContact CD2-CE1 3.64Å; L143-F208 HydrophobicContact CD2-CZ 4.29Å; L143-F208 HydrophobicContact CG-CE1 4.45Å; L143-C429 HydrophobicContact CD2-CB 3.62Å; L143-D433 WeakPolarHBondContact CA-OD2 3.36Å; L143-D433 HydrophobicContact CB-CB 4.17Å; L143-D433 VanDerWaalsContact CB-OD2 3.26Å; L143-D433 WeakPolarHBondContact CB-OD2 3.44Å; L143-D433 PolarHBondContact N-OD2 3.2Å
144F94.5Very high89Confident67 Ų6766 Ų6629%0.29432%0.317SS..Hα-helixtrans-65.3-39.8-178.7-173.3-123.9000112.4L140 P141 A146 L147 M148 A430 D433 V434L140-F144 HydrophobicContact CD2-CD1 3.98Å; L140-F144 HydrophobicContact CD2-CE1 4.1Å; P141-F144 HydrophobicContact CG-CB 4.08Å; P141-F144 PolarHBondContact O-N 3.47Å; F144-A146 VanDerWaalsContact C-N 3.33Å; F144-A146 PolarHBondContact O-N 2.95Å; F144-L147 PolarHBondContact O-N 2.97Å; F144-M148 HydrophobicContact CD1-SD 4.17Å; F144-M148 HydrophobicContact CD2-CG 4.45Å; F144-M148 HydrophobicContact CE1-CG 4.2Å; F144-M148 HydrophobicContact CE1-SD 3.55Å; F144-M148 VanDerWaalsContact CE1-SD 3.55Å; F144-M148 HydrophobicContact CE2-CG 4.08Å; F144-M148 HydrophobicContact CE2-SD 4.43Å; F144-M148 HydrophobicContact CZ-CG 3.94Å; F144-M148 HydrophobicContact CZ-SD 3.7Å; F144-M148 WeakPolarHBondContact O-CG 3.42Å; F144-M148 PolarHBondContact O-N 2.71Å; F144-A430 HydrophobicContact CD2-CB 3.95Å; F144-D433 PolarHBondContact N-OD2 2.88Å; F144-V434 HydrophobicContact CB-CG2 4.01Å; F144-V434 HydrophobicContact CD1-CG2 3.83Å; F144-V434 HydrophobicContact CE1-CG2 4.47Å; F144-V434 HydrophobicContact CG-CG2 3.89Å
145S92.8Very high88.2Confident16 Ų1666 Ų6611%0.11232%0.321CS..Hα-helixtrans-56.4-45.5171162.20000111.9P141 L143 M148 K149P141-S145 WeakPolarHBondContact O-CB 3.42Å; P141-S145 PolarHBondContact O-N 2.79Å; L143-S145 PolarHBondContact O-N 3.31Å; S145-M148 PolarHBondContact O-N 3.38Å; S145-K149 WeakPolarHBondContact O-CB 3.36Å; S145-K149 VanDerWaalsContact O-CG 3.29Å; S145-K149 WeakPolarHBondContact O-CG 3.4Å; S145-K149 PolarHBondContact O-N 3.16Å; S145-K149 PolarHBondContact OG-NZ 3.22Å
146A92Very high87.3Confident21 Ų2174.3 Ų74.317%0.17435%0.354CS..Hα-helixtrans-65.5-40.6178.900000112P142 L143 F144 Y150 L198 A207P142-A146 WeakPolarHBondContact O-CB 3.5Å; P142-A146 PolarHBondContact O-N 2.97Å; L143-A146 PolarHBondContact O-N 2.8Å; L143-A146 VanDerWaalsContact O-N 3.17Å; F144-A146 VanDerWaalsContact C-N 3.33Å; F144-A146 PolarHBondContact O-N 2.95Å; A146-Y150 VanDerWaalsContact O-CB 3.29Å; A146-Y150 WeakPolarHBondContact O-CB 3.46Å; A146-Y150 PolarHBondContact O-N 2.79Å; A146-L198 HydrophobicContact CB-CD2 3.63Å; A146-A207 HydrophobicContact CB-CB 3.61Å
147L91.2Very high86.8Confident3 Ų371.3 Ų71.32%0.01635%0.347CS..Hα-helixtrans-63.9-45176.4-69.9170.6000112.4L143 F144 Y150 S151 M191 L198 Y426 A430L143-L147 HydrophobicContact CD1-CD1 4.27Å; L143-L147 HydrophobicContact CD1-CG 4.27Å; L143-L147 HydrophobicContact CG-CD1 4.07Å; L143-L147 HydrophobicContact CG-CG 4.49Å; L143-L147 WeakPolarHBondContact O-CG 3.27Å; L143-L147 PolarHBondContact O-N 3.11Å; F144-L147 PolarHBondContact O-N 2.97Å; L147-Y150 PolarHBondContact O-N 3.35Å; L147-S151 PolarHBondContact O-N 3.37Å; L147-M191 HydrophobicContact CD2-CE 3.47Å; L147-M191 VanDerWaalsContact CD2-CE 3.47Å; L147-L198 HydrophobicContact CD2-CD1 3.73Å; L147-L198 HydrophobicContact CD2-CD2 4.19Å; L147-Y426 HydrophobicContact CD2-CD2 3.6Å; L147-Y426 HydrophobicContact CD2-CE2 4.42Å; L147-Y426 HydrophobicContact CD2-CG 4.37Å; L147-A430 HydrophobicContact CD1-CB 3.66Å
148M88.8Confident86.9Confident79 Ų7976.5 Ų76.539%0.38936%0.361SS..Hα-helixtrans-61-50.7176.8-75.1-169.366.500111.3L140 F144 S145 Y150 S151 D152L140-M148 HydrophobicContact CD1-SD 3.57Å; L140-M148 VanDerWaalsContact CD1-SD 3.57Å; F144-M148 HydrophobicContact CD1-SD 4.17Å; F144-M148 HydrophobicContact CD2-CG 4.45Å; F144-M148 HydrophobicContact CE1-CG 4.2Å; F144-M148 HydrophobicContact CE1-SD 3.55Å; F144-M148 VanDerWaalsContact CE1-SD 3.55Å; F144-M148 HydrophobicContact CE2-CG 4.08Å; F144-M148 HydrophobicContact CE2-SD 4.43Å; F144-M148 HydrophobicContact CZ-CG 3.94Å; F144-M148 HydrophobicContact CZ-SD 3.7Å; F144-M148 WeakPolarHBondContact O-CG 3.42Å; F144-M148 PolarHBondContact O-N 2.71Å; S145-M148 PolarHBondContact O-N 3.38Å; M148-Y150 PolarHBondContact O-N 2.66Å; M148-S151 PolarHBondContact O-N 3.49Å; M148-S151 VanDerWaalsContact O-N 3.16Å; M148-D152 PolarHBondContact O-N 2.95Å; M148-D152 VanDerWaalsContact O-N 3.13Å
149K87.8Confident86.9Confident129 Ų12970.6 Ų70.656%0.56134%0.338SS*.Hα-helixtrans-57.6-38.8177.8-73.2170.8-174.8167.50111.9S145 D152 I153S145-K149 WeakPolarHBondContact O-CB 3.36Å; S145-K149 VanDerWaalsContact O-CG 3.29Å; S145-K149 WeakPolarHBondContact O-CG 3.4Å; S145-K149 PolarHBondContact O-N 3.16Å; S145-K149 PolarHBondContact OG-NZ 3.22Å; K149-D152 PolarHBondContact O-N 2.79Å; K149-I153 VanDerWaalsContact O-CG1 3.3Å; K149-I153 WeakPolarHBondContact O-CG1 3.39Å
150Y85.9Confident86.9Confident26 Ų2670.5 Ų70.510%0.10235%0.348CS..Hα-helixtrans-66.3-46.5177.8-178.3-89.1000112.2A146 L147 M148 D152 I153 M191 R195 L198A146-Y150 VanDerWaalsContact O-CB 3.29Å; A146-Y150 WeakPolarHBondContact O-CB 3.46Å; A146-Y150 PolarHBondContact O-N 2.79Å; L147-Y150 PolarHBondContact O-N 3.35Å; M148-Y150 PolarHBondContact O-N 2.66Å; Y150-D152 PolarHBondContact O-N 3.46Å; Y150-I153 HydrophobicContact CD2-CD1 4.26Å; Y150-I153 WeakPolarHBondContact O-CB 3.29Å; Y150-I153 WeakPolarHBondContact O-CG1 3.42Å; Y150-I153 PolarHBondContact O-N 3.32Å; Y150-I153 VanDerWaalsContact O-N 3.08Å; Y150-M191 HydrophobicContact CD1-CE 3.71Å; Y150-M191 HydrophobicContact CD1-SD 3.18Å; Y150-M191 WeakPolarHBondContact CD1-SD 3.47Å; Y150-M191 HydrophobicContact CE1-CE 4.24Å; Y150-M191 HydrophobicContact CE1-SD 3.11Å; Y150-M191 WeakPolarHBondContact CE1-SD 3.49Å; Y150-M191 HydrophobicContact CG-CE 4.46Å; Y150-M191 HydrophobicContact CG-SD 4.29Å; Y150-R195 HydrophobicContact CE1-CG 4.44Å; Y150-R195 HydrophobicContact CE2-CB 4.4Å; Y150-R195 HydrophobicContact CE2-CG 4.27Å; Y150-R195 VanDerWaalsContact OH-CD 3.31Å; Y150-R195 WeakPolarHBondContact OH-CD 3.34Å; Y150-R195 PolarHBondContact OH-NE 3.31Å; Y150-R195 PolarHBondContact OH-NH2 2.99Å; Y150-L198 HydrophobicContact CG-CD1 4.46Å
151S84.7Confident86.9Confident18 Ų1869.2 Ų69.213%0.12634%0.343CS..Hα-helixtrans-57.5-33.4177.4-177.20000112.2L147 M148 I153L147-S151 PolarHBondContact O-N 3.37Å; M148-S151 PolarHBondContact O-N 3.49Å; M148-S151 VanDerWaalsContact O-N 3.16Å; S151-I153 VanDerWaalsContact C-N 3.29Å; S151-I153 PolarHBondContact O-N 3.33Å
152D84.3Confident86.8Confident111 Ų11172.5 Ų72.559%0.59438%0.378SS*.THydrogen-bonded Turntrans-72.9-14.2179.8-70.7-20.4000114.3M148 K149 Y150 H154M148-D152 PolarHBondContact O-N 2.95Å; M148-D152 VanDerWaalsContact O-N 3.13Å; K149-D152 PolarHBondContact O-N 2.79Å; Y150-D152 PolarHBondContact O-N 3.46Å; D152-H154 VanDerWaalsContact C-N 3.28Å; D152-H154 PolarHBondContact O-N 3.02Å; D152-H154 PolarHBondContact O-ND1 3.1Å
153I83.5Confident86.7Confident88 Ų8871.3 Ų71.345%0.45137%0.369SS..THydrogen-bonded Turntrans-72.4-23.1-179.6-50.2179.6000111.6K149 Y150 S151 E155K149-I153 VanDerWaalsContact O-CG1 3.3Å; K149-I153 WeakPolarHBondContact O-CG1 3.39Å; Y150-I153 HydrophobicContact CD2-CD1 4.26Å; Y150-I153 WeakPolarHBondContact O-CB 3.29Å; Y150-I153 WeakPolarHBondContact O-CG1 3.42Å; Y150-I153 PolarHBondContact O-N 3.32Å; Y150-I153 VanDerWaalsContact O-N 3.08Å; S151-I153 VanDerWaalsContact C-N 3.29Å; S151-I153 PolarHBondContact O-N 3.33Å; I153-E155 HydrophobicContact CG2-CB 4.41Å; I153-E155 VanDerWaalsContact CG2-CD 3.46Å; I153-E155 HydrophobicContact CG2-CG 3.71Å; I153-E155 WeakPolarHBondContact CG2-OE1 3.39Å; I153-E155 PolarHBondContact O-N 2.88Å
154H80.3Confident86.5Confident126 Ų12674.5 Ų74.558%0.58338%0.384SS*.  trans56.730178.5-65.978.5000114.8D152 R188D152-H154 VanDerWaalsContact C-N 3.28Å; D152-H154 PolarHBondContact O-N 3.02Å; D152-H154 PolarHBondContact O-ND1 3.1Å; H154-R188 PolarHBondContact CD2-NH1 2.83Å; H154-R188 PolarHBondContact NE2-NH1 3.45Å
155E76.3Confident86.2Confident125 Ų12572.4 Ų72.458%0.58438%0.381SS*.  trans-82.9139.5-179.4-86172-172.700113.2I153I153-E155 HydrophobicContact CG2-CB 4.41Å; I153-E155 VanDerWaalsContact CG2-CD 3.46Å; I153-E155 HydrophobicContact CG2-CG 3.71Å; I153-E155 WeakPolarHBondContact CG2-OE1 3.39Å; I153-E155 PolarHBondContact O-N 2.88Å
156Y74.2Confident86.2Confident197 Ų19771.7 Ų71.777%0.77338%0.376SS*.  trans-65.6152.2169.6-76.4-70000111.8R195Y156-R195 PolarHBondContact O-NH2 3.48Å
157S76.9Confident86.3Confident25 Ų2574.7 Ų74.718%0.17539%0.392CS..  trans-122.8157.5168.8-155.30000109.3A159 Q164 R195S157-A159 WeakPolarHBondContact OG-CB 3.42Å; S157-A159 PolarHBondContact OG-N 3.38Å; S157-Q164 VanDerWaalsContact C-OE1 3.29Å; S157-Q164 PolarHBondContact O-OE1 3.39Å; S157-R195 PolarHBondContact OG-NH2 2.9Å
158W85.5Confident86.4Confident239 Ų23975.8 Ų75.891%0.90540%0.404SS*.  trans-122.819.8160.9-77.1-94.9000111
159A84.4Confident86.8Confident27 Ų2775.2 Ų75.222%0.22340%0.399CS..SBendtrans-104.8166.2179.900000112.1S157 Q164 E194S157-A159 WeakPolarHBondContact OG-CB 3.42Å; S157-A159 PolarHBondContact OG-N 3.38Å; A159-Q164 PolarHBondContact O-NE2 2.98Å; A159-E194 HydrophobicContact CB-CB 4.08Å; A159-E194 HydrophobicContact CB-CG 3.88Å
160A86.8Confident87.2Confident72 Ų7271.8 Ų71.860%0.59539%0.39SS*.SBendtrans-56151.8170.900000112.2
161P91.1Very high87.8Confident33 Ų3378.5 Ų78.521%0.21442%0.419CS..SBendcis-77159.23.5-18.233.2000115.3H163 Q164P161-H163 VanDerWaalsContact CB-NE2 3.33Å; P161-H163 WeakPolarHBondContact CB-NE2 3.17Å; P161-H163 PolarHBondContact O-N 2.85Å; P161-H163 VanDerWaalsContact O-N 3.07Å; P161-Q164 PolarHBondContact O-N 3.2Å; P161-Q164 VanDerWaalsContact O-N 3.08Å; P161-Q164 PolarHBondContact O-NE2 3.07Å
162G91.7Very high88.4Confident76 Ų7681.5 Ų81.578%0.78444%0.437SS*.THydrogen-bonded Turntrans-61.7-18.7-175.700000115.7Q164G162-Q164 VanDerWaalsContact C-N 3.34Å
163H93.3Very high89Confident19 Ų1981.2 Ų81.29%0.08844%0.441CS..THydrogen-bonded Turntrans-80-11176.964.679.4000113.9P161 G165 G166 V167 G168 F169 F187 D190P161-H163 VanDerWaalsContact CB-NE2 3.33Å; P161-H163 WeakPolarHBondContact CB-NE2 3.17Å; P161-H163 PolarHBondContact O-N 2.85Å; P161-H163 VanDerWaalsContact O-N 3.07Å; H163-G165 PolarHBondContact ND1-N 3.36Å; H163-G165 PolarHBondContact O-N 2.98Å; H163-G166 PolarHBondContact ND1-N 2.93Å; H163-G166 CarbonylContact O-C 3.53Å; H163-G166 PolarHBondContact O-N 3.16Å; H163-V167 PolarHBondContact O-N 2.96Å; H163-G168 PolarHBondContact O-N 2.9Å; H163-F169 HydrophobicContact CB-CD2 3.82Å; H163-F169 HydrophobicContact CB-CE2 3.56Å; H163-F169 HydrophobicContact CB-CZ 4.21Å; H163-F169 AromaticContact CG-CE2 3.75Å; H163-F187 PolarHBondContact CE1-O 3.48Å; H163-D190 IonicContact CE1-OD2 3.3Å; H163-D190 IonicContact NE2-OD2 2.81Å; H163-D190 PolarHBondContact NE2-OD2 2.89Å; H163-D190 VanDerWaalsContact NE2-OD2 3.14Å
164Q90.6Very high89.7Confident68 Ų6880.6 Ų80.632%0.31845%0.449SS..G310 helixtrans51.557.8174.2-57.8-61.2-47.600113.3S157 A159 P161 G162 G166S157-Q164 VanDerWaalsContact C-OE1 3.29Å; S157-Q164 PolarHBondContact O-OE1 3.39Å; A159-Q164 PolarHBondContact O-NE2 2.98Å; P161-Q164 PolarHBondContact O-N 3.2Å; P161-Q164 VanDerWaalsContact O-N 3.08Å; P161-Q164 PolarHBondContact O-NE2 3.07Å; G162-Q164 VanDerWaalsContact C-N 3.34Å; Q164-G166 PolarHBondContact O-N 3.41Å
165G88.7Confident90.6Very high23 Ų2375 Ų7524%0.23743%0.426CS..G310 helixtrans74.311.2-178.500000114.7H163 F187H163-G165 PolarHBondContact ND1-N 3.36Å; H163-G165 PolarHBondContact O-N 2.98Å; G165-F187 WeakPolarHBondContact CA-O 3.44Å; G165-F187 WeakPolarHBondContact O-CB 3.19Å
166G92.5Very high91.6Very high1 Ų175.1 Ų75.11%0.0142%0.421CS..G310 helixtrans113.1-15.717400000113.7H163 Q164 G168 F169H163-G166 PolarHBondContact ND1-N 2.93Å; H163-G166 CarbonylContact O-C 3.53Å; H163-G166 PolarHBondContact O-N 3.16Å; Q164-G166 PolarHBondContact O-N 3.41Å; G166-G168 PolarHBondContact O-N 3.07Å; G166-G168 VanDerWaalsContact O-N 3.14Å; G166-F169 WeakPolarHBondContact O-CB 3.4Å; G166-F169 PolarHBondContact O-N 3.37Å
167V93.3Very high92.7Very high84 Ų8473.5 Ų73.551%0.50942%0.418SS..THydrogen-bonded Turntrans-55.9-32.3179.3-179.50000112.9H163 F169 T170H163-V167 PolarHBondContact O-N 2.96Å; V167-F169 VanDerWaalsContact C-N 3.3Å; V167-F169 PolarHBondContact O-N 3.13Å; V167-T170 PolarHBondContact O-N 2.95Å; V167-T170 PolarHBondContact O-OG1 3.16Å
168G94.8Very high93.7Very high26 Ų2677.3 Ų77.327%0.26843%0.43SS..THydrogen-bonded Turntrans-60.7-38.3174.800000113.1H163 G166 T170 K171H163-G168 PolarHBondContact O-N 2.9Å; G166-G168 PolarHBondContact O-N 3.07Å; G166-G168 VanDerWaalsContact O-N 3.14Å; G168-T170 VanDerWaalsContact C-N 3.34Å; G168-K171 WeakPolarHBondContact O-CG 3.48Å
169F96.3Very high94.2Very high66 Ų6666.6 Ų66.629%0.28939%0.39SS..G310 helixtrans-72.7-26.9179.9-65.6-62.5000112.2H163 G166 V167 K171 G175 R176 Y178 H179 F187H163-F169 HydrophobicContact CB-CD2 3.82Å; H163-F169 HydrophobicContact CB-CE2 3.56Å; H163-F169 HydrophobicContact CB-CZ 4.21Å; H163-F169 AromaticContact CG-CE2 3.75Å; G166-F169 WeakPolarHBondContact O-CB 3.4Å; G166-F169 PolarHBondContact O-N 3.37Å; V167-F169 VanDerWaalsContact C-N 3.3Å; V167-F169 PolarHBondContact O-N 3.13Å; F169-K171 PolarHBondContact O-N 3.23Å; F169-G175 CarbonylContact O-C 3.56Å; F169-G175 WeakPolarHBondContact O-CA 3.49Å; F169-R176 PolarHBondContact O-N 2.85Å; F169-Y178 HydrophobicContact CD1-CD1 4.16Å; F169-Y178 HydrophobicContact CD2-CD1 4.47Å; F169-Y178 HydrophobicContact CE1-CD1 4.29Å; F169-Y178 HydrophobicContact CE1-CE1 4.25Å; F169-Y178 HydrophobicContact CE2-CE1 4.29Å; F169-Y178 HydrophobicContact CG-CD1 4.26Å; F169-Y178 HydrophobicContact CZ-CE1 4.12Å; F169-H179 HydrophobicContact CB-CB 4.24Å; F169-F187 HydrophobicContact CD2-CD1 4.01Å; F169-F187 AromaticContact CD2-CE1 3.99Å; F169-F187 HydrophobicContact CD2-CE1 3.99Å; F169-F187 AromaticContact CE2-CD1 3.82Å; F169-F187 HydrophobicContact CE2-CD1 3.82Å; F169-F187 AromaticContact CE2-CE1 3.78Å; F169-F187 HydrophobicContact CE2-CE1 3.78Å
170T96.4Very high94.8Very high58 Ų5869.3 Ų69.336%0.35640%0.4SS..G310 helixtrans-73.61.6-179.572.50000114V167 G168V167-T170 PolarHBondContact O-N 2.95Å; V167-T170 PolarHBondContact O-OG1 3.16Å; G168-T170 VanDerWaalsContact C-N 3.34Å
171K97.3Very high95.3Very high167 Ų16774.8 Ų74.873%0.72641%0.407SS*.G310 helixtrans-82.8-13.1-176.3-63.6-178.1-179.4178.10114.2G168 F169G168-K171 WeakPolarHBondContact O-CG 3.48Å; F169-K171 PolarHBondContact O-N 3.23Å
172T97.9Very high95.5Very high81 Ų8179 Ų7950%0.49742%0.42SS..SBendtrans-135.1155.717670.50000110.6A174 G175 R176T172-A174 VanDerWaalsContact C-N 3.32Å; T172-A174 PolarHBondContact O-N 3.45Å; T172-G175 PolarHBondContact O-N 2.97Å; T172-G175 PolarHBondContact OG1-N 2.97Å; T172-G175 VanDerWaalsContact OG1-N 3.09Å; T172-R176 PolarHBondContact O-N 3.22Å
173P98.2Very high95.7Very high104 Ų10476.8 Ų76.868%0.67540%0.396SS*.Hα-helixtrans-56.7-43.6175.4-27.235.7000112.9G175 R176 F177P173-G175 PolarHBondContact O-N 2.96Å; P173-R176 PolarHBondContact O-N 3Å; P173-F177 WeakPolarHBondContact O-CD2 3.08Å; P173-F177 PolarHBondContact O-N 3.35Å
174A98.1Very high95.6Very high75 Ų7580 Ų8062%0.6241%0.411SS*.Hα-helixtrans-61.6-44.5177.700000112.2T172 R176 F177 Y178T172-A174 VanDerWaalsContact C-N 3.32Å; T172-A174 PolarHBondContact O-N 3.45Å; A174-R176 VanDerWaalsContact C-N 3.32Å; A174-R176 PolarHBondContact O-N 3.03Å; A174-F177 PolarHBondContact O-N 2.9Å; A174-Y178 PolarHBondContact O-N 3.26Å
175G97.8Very high95.7Very high10 Ų1082.5 Ų82.510%0.10343%0.427CS..Hα-helixtrans-68.1-31.2176.400000112.8F169 T172 P173 Y178 H179F169-G175 CarbonylContact O-C 3.56Å; F169-G175 WeakPolarHBondContact O-CA 3.49Å; T172-G175 PolarHBondContact O-N 2.97Å; T172-G175 PolarHBondContact OG1-N 2.97Å; T172-G175 VanDerWaalsContact OG1-N 3.09Å; P173-G175 PolarHBondContact O-N 2.96Å; G175-Y178 WeakPolarHBondContact O-CB 3.3Å; G175-Y178 PolarHBondContact O-N 3Å; G175-H179 WeakPolarHBondContact O-CB 3.39Å; G175-H179 PolarHBondContact O-N 3Å
176R97.5Very high95.8Very high126 Ų12684 Ų8448%0.47543%0.429SS..Hα-helixtrans-66.2-44.8173.1-178.264.7-168.2-141.411.1111.8F169 T172 P173 A174 Y178 H179 D180F169-R176 PolarHBondContact O-N 2.85Å; T172-R176 PolarHBondContact O-N 3.22Å; P173-R176 PolarHBondContact O-N 3Å; A174-R176 VanDerWaalsContact C-N 3.32Å; A174-R176 PolarHBondContact O-N 3.03Å; R176-Y178 VanDerWaalsContact C-N 3.27Å; R176-Y178 PolarHBondContact O-N 2.99Å; R176-H179 PolarHBondContact O-N 3.43Å; R176-D180 IonicContact CZ-OD1 2.75Å; R176-D180 IonicContact CZ-OD2 3.14Å; R176-D180 IonicContact NE-OD1 3.51Å; R176-D180 PolarHBondContact NE-OD1 2.88Å; R176-D180 IonicContact NE-OD2 3.92Å; R176-D180 PolarHBondContact NE-OD2 3.17Å; R176-D180 IonicContact NH2-OD1 3.85Å; R176-D180 PolarHBondContact NH2-OD1 3.32Å; R176-D180 VanDerWaalsContact NH2-OD1 3.14Å; R176-D180 IonicContact NH2-OD2 2.7Å; R176-D180 PolarHBondContact NH2-OD2 3.04Å; R176-D180 WeakPolarHBondContact O-CB 3.23Å; R176-D180 PolarHBondContact O-N 3.19Å
177F97.9Very high95.8Very high164 Ų16484.3 Ų84.372%0.71943%0.43SS*.Hα-helixtrans-56.8-42.7172.1-80.5-69.2000111.5P173 A174 Y181P173-F177 WeakPolarHBondContact O-CD2 3.08Å; P173-F177 PolarHBondContact O-N 3.35Å; A174-F177 PolarHBondContact O-N 2.9Å; F177-Y181 VanDerWaalsContact O-CB 3.26Å; F177-Y181 WeakPolarHBondContact O-CB 3.25Å; F177-Y181 PolarHBondContact O-N 2.75Å
178Y97.2Very high95.5Very high105 Ų10584 Ų8441%0.41242%0.42SS..Hα-helixtrans-62.7-46.8176.1-176.4-91.2000112.6F169 A174 G175 R176 Y181 Y182 F187F169-Y178 HydrophobicContact CD1-CD1 4.16Å; F169-Y178 HydrophobicContact CD2-CD1 4.47Å; F169-Y178 HydrophobicContact CE1-CD1 4.29Å; F169-Y178 HydrophobicContact CE1-CE1 4.25Å; F169-Y178 HydrophobicContact CE2-CE1 4.29Å; F169-Y178 HydrophobicContact CG-CD1 4.26Å; F169-Y178 HydrophobicContact CZ-CE1 4.12Å; A174-Y178 PolarHBondContact O-N 3.26Å; G175-Y178 WeakPolarHBondContact O-CB 3.3Å; G175-Y178 PolarHBondContact O-N 3Å; R176-Y178 VanDerWaalsContact C-N 3.27Å; R176-Y178 PolarHBondContact O-N 2.99Å; Y178-Y181 PolarHBondContact O-N 3.2Å; Y178-Y182 HydrophobicContact CD1-CD2 4.36Å; Y178-Y182 HydrophobicContact CD2-CD2 4.27Å; Y178-Y182 AromaticContact CD2-CE2 4Å; Y178-Y182 HydrophobicContact CD2-CE2 4Å; Y178-Y182 HydrophobicContact CE1-CD2 4.03Å; Y178-Y182 HydrophobicContact CE1-CE2 4.24Å; Y178-Y182 AromaticContact CE2-CD2 3.95Å; Y178-Y182 HydrophobicContact CE2-CD2 3.95Å; Y178-Y182 AromaticContact CE2-CE2 3.41Å; Y178-Y182 HydrophobicContact CE2-CE2 3.41Å; Y178-Y182 VanDerWaalsContact CE2-CE2 3.41Å; Y178-Y182 HydrophobicContact CG-CD2 4.46Å; Y178-Y182 AromaticContact CZ-CD2 3.78Å; Y178-Y182 AromaticContact CZ-CE2 3.52Å; Y178-Y182 PolarHBondContact O-N 2.74Å; Y178-F187 HydrophobicContact CD1-CE1 4.2Å; Y178-F187 AromaticContact CD1-CZ 3.85Å; Y178-F187 HydrophobicContact CD1-CZ 3.85Å; Y178-F187 AromaticContact CE1-CE1 3.62Å; Y178-F187 HydrophobicContact CE1-CE1 3.62Å; Y178-F187 AromaticContact CE1-CZ 3.63Å; Y178-F187 HydrophobicContact CE1-CZ 3.63Å
179H97.2Very high95.2Very high14 Ų1484.1 Ų84.17%0.06542%0.415CS..Hα-helixtrans-60.2-47.4177.8176.7-81.6000111.8F169 G175 R176 Y181 G183 F187F169-H179 HydrophobicContact CB-CB 4.24Å; G175-H179 WeakPolarHBondContact O-CB 3.39Å; G175-H179 PolarHBondContact O-N 3Å; R176-H179 PolarHBondContact O-N 3.43Å; H179-Y181 VanDerWaalsContact C-N 3.35Å; H179-Y181 PolarHBondContact O-N 2.64Å; H179-G183 WeakPolarHBondContact O-CA 3.42Å; H179-G183 PolarHBondContact O-N 2.76Å; H179-F187 HydrophobicContact CB-CE2 4.27Å; H179-F187 AromaticContact CD2-CD2 3.53Å; H179-F187 AromaticContact CD2-CE2 3.85Å; H179-F187 AromaticContact NE2-CD2 3.97Å
180D97.1Very high94.9Very high84 Ų8483.1 Ų83.145%0.44941%0.413SS..Hα-helixtrans-70.8-31.6-177.3-67.5-13.5000112.1R176R176-D180 IonicContact CZ-OD1 2.75Å; R176-D180 IonicContact CZ-OD2 3.14Å; R176-D180 IonicContact NE-OD1 3.51Å; R176-D180 PolarHBondContact NE-OD1 2.88Å; R176-D180 IonicContact NE-OD2 3.92Å; R176-D180 PolarHBondContact NE-OD2 3.17Å; R176-D180 IonicContact NH2-OD1 3.85Å; R176-D180 PolarHBondContact NH2-OD1 3.32Å; R176-D180 VanDerWaalsContact NH2-OD1 3.14Å; R176-D180 IonicContact NH2-OD2 2.7Å; R176-D180 PolarHBondContact NH2-OD2 3.04Å; R176-D180 WeakPolarHBondContact O-CB 3.23Å; R176-D180 PolarHBondContact O-N 3.19Å
181Y97.3Very high94.3Very high187 Ų18781.2 Ų81.273%0.73340%0.4SS*.Hα-helixtrans-63.7-46.3176.6-180-94000112.7F177 Y178 H179F177-Y181 VanDerWaalsContact O-CB 3.26Å; F177-Y181 WeakPolarHBondContact O-CB 3.25Å; F177-Y181 PolarHBondContact O-N 2.75Å; Y178-Y181 PolarHBondContact O-N 3.2Å; H179-Y181 VanDerWaalsContact C-N 3.35Å; H179-Y181 PolarHBondContact O-N 2.64Å
182Y95.2Very high93.5Very high122 Ų12274 Ų7448%0.47837%0.373SS..Hα-helixtrans-84-27.5179.8-78.6-74.7000113.7Y178 L186 F187Y178-Y182 HydrophobicContact CD1-CD2 4.36Å; Y178-Y182 HydrophobicContact CD2-CD2 4.27Å; Y178-Y182 AromaticContact CD2-CE2 4Å; Y178-Y182 HydrophobicContact CD2-CE2 4Å; Y178-Y182 HydrophobicContact CE1-CD2 4.03Å; Y178-Y182 HydrophobicContact CE1-CE2 4.24Å; Y178-Y182 AromaticContact CE2-CD2 3.95Å; Y178-Y182 HydrophobicContact CE2-CD2 3.95Å; Y178-Y182 AromaticContact CE2-CE2 3.41Å; Y178-Y182 HydrophobicContact CE2-CE2 3.41Å; Y178-Y182 VanDerWaalsContact CE2-CE2 3.41Å; Y178-Y182 HydrophobicContact CG-CD2 4.46Å; Y178-Y182 AromaticContact CZ-CD2 3.78Å; Y178-Y182 AromaticContact CZ-CE2 3.52Å; Y178-Y182 PolarHBondContact O-N 2.74Å; Y182-L186 HydrophobicContact CD1-CD2 3.65Å; Y182-L186 HydrophobicContact CE1-CD2 4.45Å; Y182-L186 HydrophobicContact CG-CD2 3.83Å; Y182-F187 HydrophobicContact CD2-CZ 4.25Å; Y182-F187 HydrophobicContact CG-CZ 4.32Å
183G94.7Very high92.6Very high28 Ų2874.5 Ų74.529%0.28937%0.372SS..  trans86.3149.5-175.500000113.7H179 N185 L186 F187H179-G183 WeakPolarHBondContact O-CA 3.42Å; H179-G183 PolarHBondContact O-N 2.76Å; G183-N185 VanDerWaalsContact C-N 3.34Å; G183-N185 PolarHBondContact O-N 3.26Å; G183-L186 PolarHBondContact O-N 2.84Å; G183-F187 WeakPolarHBondContact O-CD2 3.34Å; G183-F187 WeakPolarHBondContact O-CE2 3.49Å
184E92Very high91.2Very high86 Ų8676 Ų7640%0.40237%0.37SS..Hα-helixtrans-61.6-35.9-170.4-175.7166.7-172.500114L186 F187 R188E184-L186 VanDerWaalsContact C-N 3.28Å; E184-L186 PolarHBondContact O-N 2.98Å; E184-F187 PolarHBondContact O-N 3.18Å; E184-F187 VanDerWaalsContact O-N 3.1Å; E184-R188 HydrophobicContact CG-CG 4.06Å; E184-R188 PolarHBondContact O-N 2.79Å; E184-R188 IonicContact OE1-CZ 2.81Å; E184-R188 IonicContact OE1-NE 3.5Å; E184-R188 PolarHBondContact OE1-NE 3.17Å; E184-R188 IonicContact OE1-NH2 2.68Å; E184-R188 PolarHBondContact OE1-NH2 3.38Å
185N91.7Very high89.9Confident121 Ų12174.9 Ų74.965%0.64735%0.35SS*.Hα-helixtrans-59.6-37.4-176-71.1-23.9000112.6G183 F187 R188 T189G183-N185 VanDerWaalsContact C-N 3.34Å; G183-N185 PolarHBondContact O-N 3.26Å; N185-F187 VanDerWaalsContact C-N 3.33Å; N185-F187 PolarHBondContact O-N 2.88Å; N185-R188 PolarHBondContact O-N 3Å; N185-T189 WeakPolarHBondContact O-CG2 3.36Å; N185-T189 PolarHBondContact O-N 3.44Å; N185-T189 PolarHBondContact O-OG1 3.15Å; N185-T189 VanDerWaalsContact O-OG1 3.07Å
186L92.5Very high88.8Confident55 Ų5580.4 Ų80.429%0.28838%0.382SS..Hα-helixtrans-56.9-50.8176.2178.365.4000110.2Y182 G183 E184 R188 T189 D190 A427Y182-L186 HydrophobicContact CD1-CD2 3.65Å; Y182-L186 HydrophobicContact CE1-CD2 4.45Å; Y182-L186 HydrophobicContact CG-CD2 3.83Å; G183-L186 PolarHBondContact O-N 2.84Å; E184-L186 VanDerWaalsContact C-N 3.28Å; E184-L186 PolarHBondContact O-N 2.98Å; L186-R188 PolarHBondContact O-N 3.41Å; L186-T189 PolarHBondContact O-N 2.91Å; L186-T189 PolarHBondContact O-OG1 2.82Å; L186-D190 PolarHBondContact O-N 3.27Å; L186-A427 HydrophobicContact CD1-CB 3.95Å
187F91.5Very high88.1Confident7 Ų778.4 Ų78.43%0.03139%0.387CS..Hα-helixtrans-70.2-31-177.4-55.3-64.7000113.4H163 G165 F169 Y178 H179 Y182 G183 E184 N185 T189 D190H163-F187 PolarHBondContact CE1-O 3.48Å; G165-F187 WeakPolarHBondContact CA-O 3.44Å; G165-F187 WeakPolarHBondContact O-CB 3.19Å; F169-F187 HydrophobicContact CD2-CD1 4.01Å; F169-F187 AromaticContact CD2-CE1 3.99Å; F169-F187 HydrophobicContact CD2-CE1 3.99Å; F169-F187 AromaticContact CE2-CD1 3.82Å; F169-F187 HydrophobicContact CE2-CD1 3.82Å; F169-F187 AromaticContact CE2-CE1 3.78Å; F169-F187 HydrophobicContact CE2-CE1 3.78Å; Y178-F187 HydrophobicContact CD1-CE1 4.2Å; Y178-F187 AromaticContact CD1-CZ 3.85Å; Y178-F187 HydrophobicContact CD1-CZ 3.85Å; Y178-F187 AromaticContact CE1-CE1 3.62Å; Y178-F187 HydrophobicContact CE1-CE1 3.62Å; Y178-F187 AromaticContact CE1-CZ 3.63Å; Y178-F187 HydrophobicContact CE1-CZ 3.63Å; H179-F187 HydrophobicContact CB-CE2 4.27Å; H179-F187 AromaticContact CD2-CD2 3.53Å; H179-F187 AromaticContact CD2-CE2 3.85Å; H179-F187 AromaticContact NE2-CD2 3.97Å; Y182-F187 HydrophobicContact CD2-CZ 4.25Å; Y182-F187 HydrophobicContact CG-CZ 4.32Å; G183-F187 WeakPolarHBondContact O-CD2 3.34Å; G183-F187 WeakPolarHBondContact O-CE2 3.49Å; E184-F187 PolarHBondContact O-N 3.18Å; E184-F187 VanDerWaalsContact O-N 3.1Å; N185-F187 VanDerWaalsContact C-N 3.33Å; N185-F187 PolarHBondContact O-N 2.88Å; F187-T189 VanDerWaalsContact C-N 3.3Å; F187-D190 PolarHBondContact O-N 3.07Å
188R88.1Confident87.6Confident79 Ų7970.7 Ų70.730%0.29835%0.353SS..Hα-helixtrans-70.7-28.5174.5-72.1-161172.1-1791.8113.1H154 E184 N185 L186 M191H154-R188 PolarHBondContact CD2-NH1 2.83Å; H154-R188 PolarHBondContact NE2-NH1 3.45Å; E184-R188 HydrophobicContact CG-CG 4.06Å; E184-R188 PolarHBondContact O-N 2.79Å; E184-R188 IonicContact OE1-CZ 2.81Å; E184-R188 IonicContact OE1-NE 3.5Å; E184-R188 PolarHBondContact OE1-NE 3.17Å; E184-R188 IonicContact OE1-NH2 2.68Å; E184-R188 PolarHBondContact OE1-NH2 3.38Å; N185-R188 PolarHBondContact O-N 3Å; L186-R188 PolarHBondContact O-N 3.41Å; R188-M191 WeakPolarHBondContact O-CG 3.29Å
189T87.8Confident87.4Confident27 Ų2766.2 Ų66.217%0.16634%0.339CS..Hα-helixtrans-88.9-11.4175.461.70000114N185 L186 F187 M191N185-T189 WeakPolarHBondContact O-CG2 3.36Å; N185-T189 PolarHBondContact O-N 3.44Å; N185-T189 PolarHBondContact O-OG1 3.15Å; N185-T189 VanDerWaalsContact O-OG1 3.07Å; L186-T189 PolarHBondContact O-N 2.91Å; L186-T189 PolarHBondContact O-OG1 2.82Å; F187-T189 VanDerWaalsContact C-N 3.3Å; T189-M191 PolarHBondContact O-N 3.38Å
190D90Very high87.2Confident46 Ų4666 Ų6625%0.24634%0.338CS..  trans-79.199.3171.5-171.714.5000110.5H163 L186 F187 L425H163-D190 IonicContact CE1-OD2 3.3Å; H163-D190 IonicContact NE2-OD2 2.81Å; H163-D190 PolarHBondContact NE2-OD2 2.89Å; H163-D190 VanDerWaalsContact NE2-OD2 3.14Å; L186-D190 PolarHBondContact O-N 3.27Å; F187-D190 PolarHBondContact O-N 3.07Å; D190-L425 HydrophobicContact CB-CD1 4.16Å
191M83.4Confident87.1Confident18 Ų1862.1 Ų62.19%0.08932%0.318CS..  trans-138.1158.8-164.8-62.8-175.9-70.700112.4L147 Y150 R188 T189 L198 Y426L147-M191 HydrophobicContact CD2-CE 3.47Å; L147-M191 VanDerWaalsContact CD2-CE 3.47Å; Y150-M191 HydrophobicContact CD1-CE 3.71Å; Y150-M191 HydrophobicContact CD1-SD 3.18Å; Y150-M191 WeakPolarHBondContact CD1-SD 3.47Å; Y150-M191 HydrophobicContact CE1-CE 4.24Å; Y150-M191 HydrophobicContact CE1-SD 3.11Å; Y150-M191 WeakPolarHBondContact CE1-SD 3.49Å; Y150-M191 HydrophobicContact CG-CE 4.46Å; Y150-M191 HydrophobicContact CG-SD 4.29Å; R188-M191 WeakPolarHBondContact O-CG 3.29Å; T189-M191 PolarHBondContact O-N 3.38Å; M191-L198 HydrophobicContact CE-CD1 3.49Å; M191-L198 VanDerWaalsContact CE-CD1 3.49Å; M191-L198 HydrophobicContact SD-CD1 4.46Å; M191-Y426 HydrophobicContact CB-CD2 4.28Å; M191-Y426 HydrophobicContact CB-CE2 4.34Å; M191-Y426 HydrophobicContact CE-CD2 4.03Å; M191-Y426 HydrophobicContact CE-CE2 4.49Å
192G81Confident87Confident15 Ų1554.4 Ų54.416%0.15529%0.289CS..  trans-97.2170173.600000114.3E194 R195G192-E194 PolarHBondContact O-N 3.37Å; G192-E194 VanDerWaalsContact O-N 3.12Å; G192-R195 PolarHBondContact O-N 3.29Å
193I79.2Confident86.9Confident92 Ų9253.5 Ų53.547%0.47229%0.293SS..THydrogen-bonded Turntrans-62-16.6-179.961.1169.9000114.8R195I193-R195 PolarHBondContact O-N 2.72Å
194E67.2Low87Confident135 Ų13553.3 Ų53.363%0.63128%0.284SS*.THydrogen-bonded Turntrans-59-17.9179.2-53.8-73.5176.600112.2A159 G192 T196A159-E194 HydrophobicContact CB-CB 4.08Å; A159-E194 HydrophobicContact CB-CG 3.88Å; G192-E194 PolarHBondContact O-N 3.37Å; G192-E194 VanDerWaalsContact O-N 3.12Å; E194-T196 VanDerWaalsContact C-N 3.33Å; E194-T196 PolarHBondContact O-N 2.77Å; E194-T196 VanDerWaalsContact O-N 3.12Å
195R72.1Confident87.1Confident51 Ų5152.5 Ų52.519%0.19229%0.285CS..  trans-83.976.1172.9-55.7-51.6-167.2174.919.7110.4Y150 Y156 S157 G192 I193 S197 L198Y150-R195 HydrophobicContact CE1-CG 4.44Å; Y150-R195 HydrophobicContact CE2-CB 4.4Å; Y150-R195 HydrophobicContact CE2-CG 4.27Å; Y150-R195 VanDerWaalsContact OH-CD 3.31Å; Y150-R195 WeakPolarHBondContact OH-CD 3.34Å; Y150-R195 PolarHBondContact OH-NE 3.31Å; Y150-R195 PolarHBondContact OH-NH2 2.99Å; Y156-R195 PolarHBondContact O-NH2 3.48Å; S157-R195 PolarHBondContact OG-NH2 2.9Å; G192-R195 PolarHBondContact O-N 3.29Å; I193-R195 PolarHBondContact O-N 2.72Å; R195-S197 PolarHBondContact O-N 3.33Å; R195-L198 HydrophobicContact CB-CD1 4.39Å; R195-L198 PolarHBondContact O-N 2.84Å; R195-L198 VanDerWaalsContact O-N 3.1Å
196T74.5Confident87.3Confident127 Ų12748.7 Ų48.778%0.77928%0.275SS*.THydrogen-bonded Turntrans-54.1-23.1-175.955.70000115E194 L198 G199E194-T196 VanDerWaalsContact C-N 3.33Å; E194-T196 PolarHBondContact O-N 2.77Å; E194-T196 VanDerWaalsContact O-N 3.12Å; T196-L198 VanDerWaalsContact C-N 3.26Å; T196-L198 PolarHBondContact O-N 2.86Å; T196-G199 PolarHBondContact O-N 3.16Å
197S81.8Confident87.4Confident84 Ų8446.7 Ų46.759%0.58727%0.266SS*.THydrogen-bonded Turntrans-65.1-24178.453.70000114.3R195R195-S197 PolarHBondContact O-N 3.33Å
198L89Confident87.7Confident2 Ų246.4 Ų46.41%0.0127%0.265CS..THydrogen-bonded Turntrans-89.2-22.7179.6-64172.8000112.7A146 L147 Y150 M191 R195 T196 A207 Y426A146-L198 HydrophobicContact CB-CD2 3.63Å; L147-L198 HydrophobicContact CD2-CD1 3.73Å; L147-L198 HydrophobicContact CD2-CD2 4.19Å; Y150-L198 HydrophobicContact CG-CD1 4.46Å; M191-L198 HydrophobicContact CE-CD1 3.49Å; M191-L198 VanDerWaalsContact CE-CD1 3.49Å; M191-L198 HydrophobicContact SD-CD1 4.46Å; R195-L198 HydrophobicContact CB-CD1 4.39Å; R195-L198 PolarHBondContact O-N 2.84Å; R195-L198 VanDerWaalsContact O-N 3.1Å; T196-L198 VanDerWaalsContact C-N 3.26Å; T196-L198 PolarHBondContact O-N 2.86Å; L198-A207 WeakPolarHBondContact O-CB 3.06Å; L198-A207 PolarHBondContact O-N 3.07Å; L198-Y426 HydrophobicContact CD1-CD2 4.19Å; L198-Y426 HydrophobicContact CD1-CE2 3.77Å
199G92.5Very high88.1Confident10 Ų1042.9 Ų42.910%0.10325%0.254CS..EExtended strand (participates in β ladder)trans82.6-159.2-169.100000112.9T196 T205T196-G199 PolarHBondContact O-N 3.16Å; G199-T205 WeakPolarHBondContact CA-O 3.37Å
200S93.8Very high88.5Confident9 Ų946 Ų466%0.06327%0.266CS..EExtended strand (participates in β ladder)trans-140.4132.8-171.8165.60000110.8L202 D203 H204 T205S200-L202 PolarHBondContact OG-N 2.62Å; S200-D203 WeakPolarHBondContact CB-OD2 3.44Å; S200-D203 PolarHBondContact OG-N 3.24Å; S200-D203 PolarHBondContact OG-OD2 2.9Å; S200-H204 PolarHBondContact O-N 3.11Å; S200-T205 PolarHBondContact N-O 3.3Å; S200-T205 PolarHBondContact N-OG1 3.31Å; S200-T205 PolarHBondContact O-N 3.15Å; S200-T205 VanDerWaalsContact O-N 3.16Å
201L94.5Very high88.9Confident3 Ų343.9 Ų43.92%0.01626%0.255CS..THydrogen-bonded Turntrans-64.6-38.1175.2178.565.8000112.1H204 F208 V228 Y416 P424L201-H204 PolarHBondContact O-CE1 2.9Å; L201-F208 HydrophobicContact CB-CD1 3.79Å; L201-F208 HydrophobicContact CB-CE1 3.91Å; L201-F208 HydrophobicContact CB-CG 4.22Å; L201-F208 HydrophobicContact CB-CZ 4.45Å; L201-F208 HydrophobicContact CD1-CD1 3.83Å; L201-F208 HydrophobicContact CD1-CE1 4.29Å; L201-F208 HydrophobicContact CG-CD1 4.39Å; L201-V228 HydrophobicContact CD2-CG1 4.45Å; L201-V228 HydrophobicContact CD2-CG2 4.41Å; L201-Y416 WeakPolarHBondContact CD1-OH 3Å; L201-Y416 WeakPolarHBondContact CG-OH 3.43Å; L201-P424 HydrophobicContact CB-CG 4.2Å; L201-P424 HydrophobicContact CD2-CB 3.64Å; L201-P424 HydrophobicContact CD2-CG 3.72Å
202L94.7Very high89.6Confident25 Ų2543.7 Ų43.713%0.13125%0.254CS..THydrogen-bonded Turntrans-78.8-31.1-177.1-70.2165.8000112.4S200 H204 N413 Y416 M417 A420 T422S200-L202 PolarHBondContact OG-N 2.62Å; L202-H204 PolarHBondContact O-CD2 3.27Å; L202-N413 PolarHBondContact O-ND2 3.05Å; L202-Y416 HydrophobicContact CD2-CE1 4.21Å; L202-M417 HydrophobicContact CD2-CB 4.36Å; L202-M417 HydrophobicContact CD2-CG 3.9Å; L202-A420 HydrophobicContact CD2-CB 3.57Å; L202-T422 HydrophobicContact CD1-CG2 4.11Å
203D93.7Very high90.5Very high103 Ų10349 Ų4955%0.55127%0.273SS*.THydrogen-bonded Turntrans-91.1-8.1178.9-54.3-57.7000112.5S200 T205S200-D203 WeakPolarHBondContact CB-OD2 3.44Å; S200-D203 PolarHBondContact OG-N 3.24Å; S200-D203 PolarHBondContact OG-OD2 2.9Å; D203-T205 HydrophobicContact CB-CG2 4.03Å; D203-T205 WeakPolarHBondContact O-CG2 3.1Å; D203-T205 PolarHBondContact O-N 2.91Å
204H95.5Very high91.3Very high25 Ų2546.6 Ų46.612%0.11626%0.258CS..THydrogen-bonded Turntrans57.345.3-177.7-53.8-77.4000112.9S200 L201 L202 E212 W225 F409 N413 Y416S200-H204 PolarHBondContact O-N 3.11Å; L201-H204 PolarHBondContact O-CE1 2.9Å; L202-H204 PolarHBondContact O-CD2 3.27Å; H204-E212 IonicContact CE1-OE1 2.64Å; H204-E212 PolarHBondContact CE1-OE1 2.88Å; H204-E212 IonicContact CE1-OE2 3.78Å; H204-E212 IonicContact CG-OE2 3.65Å; H204-E212 VanDerWaalsContact ND1-CD 3.27Å; H204-E212 IonicContact ND1-OE1 3.86Å; H204-E212 PolarHBondContact ND1-OE1 3.3Å; H204-E212 IonicContact ND1-OE2 3.47Å; H204-E212 PolarHBondContact ND1-OE2 3.42Å; H204-W225 AromaticContact CE1-CD1 3.25Å; H204-W225 AromaticContact CE1-NE1 3.45Å; H204-W225 PolarHBondContact CE1-NE1 2.81Å; H204-W225 AromaticContact NE2-CD1 3.77Å; H204-W225 AromaticContact NE2-NE1 3.58Å; H204-F409 HydrophobicContact CB-CZ 4.06Å; H204-F409 AromaticContact CD2-CZ 3.44Å; H204-F409 VanDerWaalsContact CD2-CZ 3.44Å; H204-F409 WeakPolarHBondContact CD2-CZ 3.28Å; H204-F409 AromaticContact CG-CZ 3.79Å; H204-N413 PolarHBondContact NE2-OD1 2.81Å; H204-Y416 AromaticContact CE1-CE1 3.72Å; H204-Y416 AromaticContact NE2-CD1 3.84Å; H204-Y416 AromaticContact NE2-CE1 3.84Å
205T95.5Very high92.8Very high68 Ų6840.1 Ų40.142%0.41723%0.228SC..EExtended strand (participates in β ladder)trans-121.1164.3-174.958.60000112.7G199 S200 D203 F208 G209G199-T205 WeakPolarHBondContact CA-O 3.37Å; S200-T205 PolarHBondContact N-O 3.3Å; S200-T205 PolarHBondContact N-OG1 3.31Å; S200-T205 PolarHBondContact O-N 3.15Å; S200-T205 VanDerWaalsContact O-N 3.16Å; D203-T205 HydrophobicContact CB-CG2 4.03Å; D203-T205 WeakPolarHBondContact O-CG2 3.1Å; D203-T205 PolarHBondContact O-N 2.91Å; T205-F208 PolarHBondContact O-N 3.05Å; T205-G209 PolarHBondContact O-N 2.85Å
206G95Very high94.1Very high42 Ų4238.1 Ų38.143%0.43322%0.222SC..Hα-helixtrans59.5-141.3178.100000112.5F208 G209 E210G206-F208 PolarHBondContact O-N 3.32Å; G206-G209 PolarHBondContact O-N 2.95Å; G206-E210 PolarHBondContact O-N 2.89Å; G206-E210 VanDerWaalsContact O-N 3.12Å
207A95.4Very high95.2Very high13 Ų1338.4 Ų38.411%0.10721%0.209CC..Hα-helixtrans-65.1-28.3-176.900000112.7L143 A146 L198 S211L143-A207 HydrophobicContact CD1-CB 4.09Å; A146-A207 HydrophobicContact CB-CB 3.61Å; L198-A207 WeakPolarHBondContact O-CB 3.06Å; L198-A207 PolarHBondContact O-N 3.07Å; A207-S211 WeakPolarHBondContact O-CB 3.5Å; A207-S211 PolarHBondContact O-N 3.12Å; A207-S211 PolarHBondContact O-OG 3.37Å
208F96.1Very high95.9Very high0 Ų035 Ų350%018%0.184CC..Hα-helixtrans-62.7-52.4171.6-73.3-81.2000111.8L143 L201 T205 G206 E210 S211 E212 Y426 C429L143-F208 HydrophobicContact CD1-CD1 4.09Å; L143-F208 HydrophobicContact CD1-CD2 4.08Å; L143-F208 HydrophobicContact CD1-CE1 3.91Å; L143-F208 HydrophobicContact CD1-CE2 3.9Å; L143-F208 HydrophobicContact CD1-CG 4.18Å; L143-F208 HydrophobicContact CD1-CZ 3.8Å; L143-F208 HydrophobicContact CD2-CD1 3.84Å; L143-F208 HydrophobicContact CD2-CE1 3.64Å; L143-F208 HydrophobicContact CD2-CZ 4.29Å; L143-F208 HydrophobicContact CG-CE1 4.45Å; L201-F208 HydrophobicContact CB-CD1 3.79Å; L201-F208 HydrophobicContact CB-CE1 3.91Å; L201-F208 HydrophobicContact CB-CG 4.22Å; L201-F208 HydrophobicContact CB-CZ 4.45Å; L201-F208 HydrophobicContact CD1-CD1 3.83Å; L201-F208 HydrophobicContact CD1-CE1 4.29Å; L201-F208 HydrophobicContact CG-CD1 4.39Å; T205-F208 PolarHBondContact O-N 3.05Å; G206-F208 PolarHBondContact O-N 3.32Å; F208-E210 VanDerWaalsContact C-N 3.28Å; F208-E210 PolarHBondContact O-N 3.44Å; F208-S211 PolarHBondContact O-N 3Å; F208-S211 VanDerWaalsContact O-N 3.13Å; F208-S211 PolarHBondContact O-OG 3.09Å; F208-E212 PolarHBondContact O-N 2.88Å; F208-Y426 HydrophobicContact CE2-CE1 4.09Å; F208-Y426 HydrophobicContact CE2-CE2 4.04Å; F208-Y426 AromaticContact CE2-CZ 3.73Å; F208-Y426 AromaticContact CZ-CD1 3.79Å; F208-Y426 HydrophobicContact CZ-CD1 3.79Å; F208-Y426 HydrophobicContact CZ-CD2 4.23Å; F208-Y426 AromaticContact CZ-CE1 3.56Å; F208-Y426 HydrophobicContact CZ-CE1 3.56Å; F208-Y426 AromaticContact CZ-CE2 3.99Å; F208-Y426 HydrophobicContact CZ-CE2 3.99Å; F208-Y426 HydrophobicContact CZ-CG 4.12Å; F208-Y426 AromaticContact CZ-CZ 3.65Å; F208-C429 HydrophobicContact CE1-CB 3.77Å
209G97Very high96.4Very high6 Ų635 Ų356%0.06218%0.184CC..Hα-helixtrans-61.1-35.6178.500000113.1T205 G206 K213T205-G209 PolarHBondContact O-N 2.85Å; G206-G209 PolarHBondContact O-N 2.95Å; G209-K213 WeakPolarHBondContact O-CG 3.48Å; G209-K213 PolarHBondContact O-N 3.29Å
210E97.5Very high96.6Very high93 Ų9334.5 Ų34.544%0.43518%0.179SC..Hα-helixtrans-70.6-37.6174.2-62.5-50.6125.400112.7P142 G206 F208 E212 K213 Y214P142-E210 HydrophobicContact CB-CB 3.88Å; P142-E210 HydrophobicContact CG-CB 4.28Å; G206-E210 PolarHBondContact O-N 2.89Å; G206-E210 VanDerWaalsContact O-N 3.12Å; F208-E210 VanDerWaalsContact C-N 3.28Å; F208-E210 PolarHBondContact O-N 3.44Å; E210-E212 VanDerWaalsContact C-N 3.31Å; E210-E212 PolarHBondContact O-N 2.82Å; E210-K213 PolarHBondContact O-N 3.49Å; E210-K213 IonicContact OE1-NZ 2.72Å; E210-K213 PolarHBondContact OE1-NZ 2.83Å; E210-K213 IonicContact OE2-NZ 3.76Å; E210-Y214 WeakPolarHBondContact O-CB 3.42Å; E210-Y214 PolarHBondContact O-N 3.4Å
211S97.8Very high96.8Very high1 Ų134.3 Ų34.31%0.00718%0.178CC..Hα-helixtrans-62.6-36.6174.171.20000112.7A207 F208 Y214 A215 D433A207-S211 WeakPolarHBondContact O-CB 3.5Å; A207-S211 PolarHBondContact O-N 3.12Å; A207-S211 PolarHBondContact O-OG 3.37Å; F208-S211 PolarHBondContact O-N 3Å; F208-S211 VanDerWaalsContact O-N 3.13Å; F208-S211 PolarHBondContact O-OG 3.09Å; S211-Y214 WeakPolarHBondContact O-CB 3.3Å; S211-Y214 PolarHBondContact O-N 3.2Å; S211-A215 WeakPolarHBondContact O-CB 3.37Å; S211-A215 PolarHBondContact O-N 3.35Å; S211-D433 WeakPolarHBondContact CB-OD1 3.49Å
212E98.5Very high97Very high13 Ų1337.1 Ų37.16%0.06119%0.193CC..Hα-helixtrans-69.8-39.3177.7-75.4176.7152.600112.4H204 F208 E210 Y214 A215 A216 S224 S226H204-E212 IonicContact CE1-OE1 2.64Å; H204-E212 PolarHBondContact CE1-OE1 2.88Å; H204-E212 IonicContact CE1-OE2 3.78Å; H204-E212 IonicContact CG-OE2 3.65Å; H204-E212 VanDerWaalsContact ND1-CD 3.27Å; H204-E212 IonicContact ND1-OE1 3.86Å; H204-E212 PolarHBondContact ND1-OE1 3.3Å; H204-E212 IonicContact ND1-OE2 3.47Å; H204-E212 PolarHBondContact ND1-OE2 3.42Å; F208-E212 PolarHBondContact O-N 2.88Å; E210-E212 VanDerWaalsContact C-N 3.31Å; E210-E212 PolarHBondContact O-N 2.82Å; E212-Y214 VanDerWaalsContact C-N 3.35Å; E212-A215 PolarHBondContact O-N 3.25Å; E212-A216 WeakPolarHBondContact O-CB 3.37Å; E212-A216 PolarHBondContact O-N 3.5Å; E212-S224 WeakPolarHBondContact CB-O 3.4Å; E212-S226 PolarHBondContact OE1-N 3.01Å
213K98.3Very high97.1Very high127 Ų12740.8 Ų40.855%0.55221%0.205SC*.Hα-helixtrans-64.9-40.6171.3-67.9170.3-169.3168.50111.5G209 E210 A216 R217G209-K213 WeakPolarHBondContact O-CG 3.48Å; G209-K213 PolarHBondContact O-N 3.29Å; E210-K213 PolarHBondContact O-N 3.49Å; E210-K213 IonicContact OE1-NZ 2.72Å; E210-K213 PolarHBondContact OE1-NZ 2.83Å; E210-K213 IonicContact OE2-NZ 3.76Å; K213-A216 PolarHBondContact O-N 2.98Å; K213-R217 PolarHBondContact O-N 2.72Å
214Y98Very high97.3Very high41 Ų4136.1 Ų36.116%0.16118%0.181CC..Hα-helixtrans-60.9-47.6176-178.2-115.8000111P141 E210 S211 E212 A216 R217 V218 V436 S437 D440P141-Y214 HydrophobicContact CB-CD1 4.28Å; P141-Y214 HydrophobicContact CB-CE1 4Å; E210-Y214 WeakPolarHBondContact O-CB 3.42Å; E210-Y214 PolarHBondContact O-N 3.4Å; S211-Y214 WeakPolarHBondContact O-CB 3.3Å; S211-Y214 PolarHBondContact O-N 3.2Å; E212-Y214 VanDerWaalsContact C-N 3.35Å; Y214-A216 PolarHBondContact O-N 3.02Å; Y214-R217 PolarHBondContact O-N 3.02Å; Y214-V218 HydrophobicContact CE1-CG2 4.47Å; Y214-V218 HydrophobicContact CE2-CG2 4.23Å; Y214-V218 WeakPolarHBondContact O-CG2 3.43Å; Y214-V218 PolarHBondContact O-N 3.3Å; Y214-V436 HydrophobicContact CD1-CB 4.26Å; Y214-V436 HydrophobicContact CD1-CG1 3.52Å; Y214-V436 HydrophobicContact CE1-CB 4.17Å; Y214-V436 HydrophobicContact CE1-CG1 3.51Å; Y214-V436 HydrophobicContact CG-CG1 4.4Å; Y214-S437 WeakPolarHBondContact OH-CA 3.27Å; Y214-D440 WeakPolarHBondContact CE2-OD2 3.31Å; Y214-D440 WeakPolarHBondContact OH-CB 3.41Å; Y214-D440 PolarHBondContact OH-OD2 3.31Å
215A98.5Very high97.5Very high0 Ų035.4 Ų35.40%018%0.177CC..Hα-helixtrans-58.5-45.8173.400000112.5S211 E212 R217 V218 F219 Y397 V436S211-A215 WeakPolarHBondContact O-CB 3.37Å; S211-A215 PolarHBondContact O-N 3.35Å; E212-A215 PolarHBondContact O-N 3.25Å; A215-R217 VanDerWaalsContact C-N 3.33Å; A215-R217 PolarHBondContact O-N 3.37Å; A215-V218 PolarHBondContact O-N 3.13Å; A215-F219 WeakPolarHBondContact O-CB 3.28Å; A215-F219 WeakPolarHBondContact O-CD2 3.33Å; A215-F219 PolarHBondContact O-N 3.39Å; A215-Y397 HydrophobicContact CB-CD1 4.35Å; A215-Y397 HydrophobicContact CB-CE1 3.73Å; A215-V436 HydrophobicContact CB-CG1 4.25Å; A215-V436 HydrophobicContact CB-CG2 3.72Å
216A98.5Very high97.6Very high8 Ų832.2 Ų32.27%0.06616%0.157CC..Hα-helixtrans-58.8-42.8177.600000112.3E212 K213 Y214 G220 A221 S224E212-A216 WeakPolarHBondContact O-CB 3.37Å; E212-A216 PolarHBondContact O-N 3.5Å; K213-A216 PolarHBondContact O-N 2.98Å; Y214-A216 PolarHBondContact O-N 3.02Å; A216-G220 CarbonylContact O-C 3.57Å; A216-G220 WeakPolarHBondContact O-CA 3.49Å; A216-G220 PolarHBondContact O-N 2.85Å; A216-A221 PolarHBondContact O-N 2.84Å; A216-S224 WeakPolarHBondContact CA-OG 3.26Å; A216-S224 PolarHBondContact N-OG 3.03Å
217R97.5Very high97.7Very high134 Ų13430.4 Ų30.451%0.50614%0.138SC..Hα-helixtrans-62-51.3175.2-177.4-172.363.397.411.4112K213 Y214 A215 G220 D440K213-R217 PolarHBondContact O-N 2.72Å; Y214-R217 PolarHBondContact O-N 3.02Å; A215-R217 VanDerWaalsContact C-N 3.33Å; A215-R217 PolarHBondContact O-N 3.37Å; R217-G220 PolarHBondContact O-N 3.29Å; R217-D440 IonicContact CZ-OD1 3.34Å; R217-D440 IonicContact CZ-OD2 2.55Å; R217-D440 IonicContact NH1-OD1 3.85Å; R217-D440 IonicContact NH1-OD2 3.59Å; R217-D440 VanDerWaalsContact NH2-CG 3.3Å; R217-D440 IonicContact NH2-OD1 3.77Å; R217-D440 PolarHBondContact NH2-OD1 3.11Å; R217-D440 IonicContact NH2-OD2 3.14Å; R217-D440 PolarHBondContact NH2-OD2 2.96Å
218V97.3Very high97.8Very high12 Ų1230.2 Ų30.27%0.07314%0.135CC..Hα-helixtrans-65.2-45.5-174.6172.50000111.4Y214 A215 G220 R356 F357 V436 M439 D440Y214-V218 HydrophobicContact CE1-CG2 4.47Å; Y214-V218 HydrophobicContact CE2-CG2 4.23Å; Y214-V218 WeakPolarHBondContact O-CG2 3.43Å; Y214-V218 PolarHBondContact O-N 3.3Å; A215-V218 PolarHBondContact O-N 3.13Å; V218-G220 PolarHBondContact O-N 3.16Å; V218-R356 PolarHBondContact O-NE 3.44Å; V218-F357 HydrophobicContact CG1-CE1 3.76Å; V218-F357 HydrophobicContact CG1-CZ 4.11Å; V218-V436 HydrophobicContact CB-CG1 3.76Å; V218-V436 HydrophobicContact CG1-CG1 4.06Å; V218-V436 HydrophobicContact CG2-CG1 3.75Å; V218-M439 HydrophobicContact CG1-CB 4.33Å; V218-D440 HydrophobicContact CG1-CB 4.39Å; V218-D440 HydrophobicContact CG2-CB 3.9Å
219F98.1Very high97.9Very high2 Ų232.4 Ų32.41%0.00915%0.149CC..THydrogen-bonded Turntrans-80.7-0.7178.9-75.9-97.6000113.3A215 G353 R356 F357 M367 H383 L389 H399 V436A215-F219 WeakPolarHBondContact O-CB 3.28Å; A215-F219 WeakPolarHBondContact O-CD2 3.33Å; A215-F219 PolarHBondContact O-N 3.39Å; F219-G353 WeakPolarHBondContact CE1-O 3.39Å; F219-R356 VanDerWaalsContact C-NE 3.32Å; F219-R356 WeakPolarHBondContact O-CD 3.45Å; F219-R356 PolarHBondContact O-NE 3.27Å; F219-F357 HydrophobicContact CD1-CE2 4.35Å; F219-F357 AromaticContact CD1-CZ 3.89Å; F219-F357 HydrophobicContact CD1-CZ 3.89Å; F219-F357 HydrophobicContact CD2-CZ 4.27Å; F219-F357 AromaticContact CE1-CE2 3.77Å; F219-F357 HydrophobicContact CE1-CE2 3.77Å; F219-F357 AromaticContact CE1-CZ 3.64Å; F219-F357 HydrophobicContact CE1-CZ 3.64Å; F219-F357 HydrophobicContact CE2-CZ 4.01Å; F219-F357 HydrophobicContact CG-CZ 4.21Å; F219-F357 AromaticContact CZ-CE2 3.95Å; F219-F357 HydrophobicContact CZ-CE2 3.95Å; F219-F357 AromaticContact CZ-CZ 3.7Å; F219-F357 HydrophobicContact CZ-CZ 3.7Å; F219-M367 VanDerWaalsContact O-CB 3.24Å; F219-M367 WeakPolarHBondContact O-CB 3.3Å; F219-H383 AromaticContact CD1-CE1 3.76Å; F219-H383 AromaticContact CD1-ND1 3.62Å; F219-H383 AromaticContact CE1-CE1 3.95Å; F219-H383 AromaticContact CE1-ND1 3.48Å; F219-H383 WeakPolarHBondContact CE1-ND1 3.24Å; F219-L389 HydrophobicContact CE1-CD1 4.12Å; F219-L389 HydrophobicContact CZ-CD1 3.74Å; F219-H399 AromaticContact CD1-CE1 3.84Å; F219-H399 AromaticContact CD1-NE2 3.48Å; F219-H399 WeakPolarHBondContact CD1-NE2 3.46Å; F219-H399 AromaticContact CD2-CE1 3.82Å; F219-H399 AromaticContact CE1-NE2 3.94Å; F219-H399 AromaticContact CG-CE1 3.45Å; F219-H399 VanDerWaalsContact CG-CE1 3.45Å; F219-H399 WeakPolarHBondContact CG-CE1 3.35Å; F219-H399 AromaticContact CG-NE2 3.61Å; F219-V436 HydrophobicContact CD2-CG2 4.43Å; F219-V436 HydrophobicContact CE2-CB 4.34Å; F219-V436 HydrophobicContact CE2-CG1 4.35Å; F219-V436 HydrophobicContact CE2-CG2 3.83Å
220G97.5Very high97.9Very high0 Ų032.6 Ų32.60%015%0.15CC..THydrogen-bonded Turntrans58.451.8-178.900000111.9A216 R217 V218 R401A216-G220 CarbonylContact O-C 3.57Å; A216-G220 WeakPolarHBondContact O-CA 3.49Å; A216-G220 PolarHBondContact O-N 2.85Å; R217-G220 PolarHBondContact O-N 3.29Å; V218-G220 PolarHBondContact O-N 3.16Å; G220-R401 PolarHBondContact O-NH1 3.04Å; G220-R401 PolarHBondContact O-NH2 3.12Å
221A98.1Very high97.9Very high4 Ų428.5 Ų28.53%0.03313%0.132CC..  trans-114.2158.5173.400000110A216 R223 M367 H399A216-A221 PolarHBondContact O-N 2.84Å; A221-R223 VanDerWaalsContact C-N 3.33Å; A221-R223 WeakPolarHBondContact CB-O 3.47Å; A221-M367 HydrophobicContact CB-SD 3.92Å; A221-H399 HydrophobicContact CB-CB 3.88Å
222D97.9Very high97.9Very high63 Ų6330.3 Ų30.334%0.33714%0.144SC..SBendtrans-70.7-36.7169-68.8-76.4000110.8P371 V400 R401 E402D222-P371 WeakPolarHBondContact OD1-CB 3.45Å; D222-V400 PolarHBondContact N-O 3.3Å; D222-R401 VanDerWaalsContact OD2-CA 3.3Å; D222-R401 WeakPolarHBondContact OD2-CA 3.46Å; D222-R401 VanDerWaalsContact OD2-CD 3.27Å; D222-R401 WeakPolarHBondContact OD2-CD 3.48Å; D222-R401 IonicContact OD2-NH1 3.82Å; D222-E402 HydrophobicContact CB-CB 4.35Å; D222-E402 HydrophobicContact CB-CG 3.99Å; D222-E402 PolarHBondContact OD2-N 3.48Å
223R97.6Very high97.8Very high101 Ų10129.7 Ų29.738%0.38114%0.142SC..EExtended strand (participates in β ladder)trans-143149.4178.4-63-176.7-173.6-82.7-9111A221 W225 V400 E402A221-R223 VanDerWaalsContact C-N 3.33Å; A221-R223 WeakPolarHBondContact CB-O 3.47Å; R223-W225 HydrophobicContact CB-CE3 4.25Å; R223-W225 HydrophobicContact CB-CH2 3.84Å; R223-W225 HydrophobicContact CB-CZ3 3.47Å; R223-W225 VanDerWaalsContact CB-CZ3 3.47Å; R223-W225 HydrophobicContact CG-CH2 4.37Å; R223-W225 HydrophobicContact CG-CZ3 4.45Å; R223-V400 PolarHBondContact N-O 3.01Å; R223-V400 PolarHBondContact O-N 2.95Å; R223-E402 WeakPolarHBondContact CD-OE1 3.24Å; R223-E402 IonicContact CZ-OE1 2.66Å; R223-E402 IonicContact NE-OE1 2.76Å; R223-E402 PolarHBondContact NE-OE1 3.12Å; R223-E402 IonicContact NH2-OE1 3.91Å
224S98.5Very high97.8Very high6 Ų623.6 Ų23.64%0.04212%0.115CC..EExtended strand (participates in β ladder)trans-132.7142.2169.5-58.90000110.4E212 A216 I398 H399E212-S224 WeakPolarHBondContact CB-O 3.4Å; A216-S224 WeakPolarHBondContact CA-OG 3.26Å; A216-S224 PolarHBondContact N-OG 3.03Å; S224-I398 CarbonylContact C-O 3.55Å; S224-I398 WeakPolarHBondContact CA-O 3.48Å; S224-H399 PolarHBondContact OG-ND1 3.38Å
225W98.3Very high97.9Very high9 Ų921.7 Ų21.73%0.03411%0.108CC..EExtended strand (participates in β ladder)trans-113.9126.5170.8-76.6-103.8000109.3H204 R223 Y397 I398 V400 F409 F412 Y416H204-W225 AromaticContact CE1-CD1 3.25Å; H204-W225 AromaticContact CE1-NE1 3.45Å; H204-W225 PolarHBondContact CE1-NE1 2.81Å; H204-W225 AromaticContact NE2-CD1 3.77Å; H204-W225 AromaticContact NE2-NE1 3.58Å; R223-W225 HydrophobicContact CB-CE3 4.25Å; R223-W225 HydrophobicContact CB-CH2 3.84Å; R223-W225 HydrophobicContact CB-CZ3 3.47Å; R223-W225 VanDerWaalsContact CB-CZ3 3.47Å; R223-W225 HydrophobicContact CG-CH2 4.37Å; R223-W225 HydrophobicContact CG-CZ3 4.45Å; W225-Y397 WeakPolarHBondContact O-CA 3.37Å; W225-Y397 VanDerWaalsContact O-CD1 3.3Å; W225-Y397 WeakPolarHBondContact O-CD1 3.35Å; W225-I398 HydrophobicContact CB-CB 4.27Å; W225-I398 HydrophobicContact CB-CD1 4.47Å; W225-I398 PolarHBondContact N-O 2.96Å; W225-I398 PolarHBondContact O-N 2.86Å; W225-V400 HydrophobicContact CE3-CG2 4.07Å; W225-V400 HydrophobicContact CH2-CG2 4.5Å; W225-V400 HydrophobicContact CZ3-CB 4.17Å; W225-V400 HydrophobicContact CZ3-CG2 3.51Å; W225-F409 HydrophobicContact CH2-CD2 4.45Å; W225-F409 AromaticContact CZ2-CD2 3.71Å; W225-F409 HydrophobicContact CZ2-CD2 3.71Å; W225-F409 AromaticContact CZ2-CE2 3.86Å; W225-F409 HydrophobicContact CZ2-CE2 3.86Å; W225-F412 AromaticContact CD2-CD1 3.97Å; W225-F412 HydrophobicContact CD2-CD1 3.97Å; W225-F412 AromaticContact CD2-CE1 3.75Å; W225-F412 HydrophobicContact CD2-CE1 3.75Å; W225-F412 AromaticContact CE2-CD1 3.57Å; W225-F412 AromaticContact CE2-CE1 3.87Å; W225-F412 HydrophobicContact CE3-CD1 4.28Å; W225-F412 AromaticContact CE3-CE1 3.92Å; W225-F412 HydrophobicContact CE3-CE1 3.92Å; W225-F412 HydrophobicContact CG-CE1 4.22Å; W225-F412 AromaticContact CH2-CD1 3.85Å; W225-F412 HydrophobicContact CH2-CD1 3.85Å; W225-F412 HydrophobicContact CH2-CE1 4.28Å; W225-F412 HydrophobicContact CH2-CG 4.25Å; W225-F412 HydrophobicContact CZ2-CB 4.37Å; W225-F412 AromaticContact CZ2-CD1 3.52Å; W225-F412 HydrophobicContact CZ2-CD1 3.52Å; W225-F412 HydrophobicContact CZ2-CE1 4.14Å; W225-F412 HydrophobicContact CZ2-CG 4.16Å; W225-F412 HydrophobicContact CZ3-CD1 4.23Å; W225-F412 HydrophobicContact CZ3-CE1 4.19Å; W225-Y416 HydrophobicContact CB-CD2 4.27Å; W225-Y416 HydrophobicContact CB-CE2 4.16Å; W225-Y416 AromaticContact CD1-CD2 3.76Å; W225-Y416 AromaticContact CD1-CG 3.9Å; W225-Y416 HydrophobicContact CG-CD2 4.3Å
226S98.1Very high97.8Very high1 Ų124.6 Ų24.61%0.00712%0.119CC..EExtended strand (participates in β ladder)trans-75.9128.5170.9-1720000109.4E212 Y416 N432E212-S226 PolarHBondContact OE1-N 3.01Å; S226-Y416 WeakPolarHBondContact O-CE2 3.41Å; S226-Y416 PolarHBondContact O-OH 3.27Å; S226-N432 PolarHBondContact OG-ND2 2.91Å
227V98.2Very high97.8Very high4 Ų424.3 Ų24.32%0.02412%0.116CC..EExtended strand (participates in β ladder)trans-123132.1-177.5177.50000109.9V229 S234 S396 I398 Y416V227-V229 HydrophobicContact CG1-CG2 3.61Å; V227-S234 WeakPolarHBondContact CG2-OG 3.3Å; V227-S396 PolarHBondContact N-O 3.44Å; V227-S396 PolarHBondContact O-N 3.07Å; V227-I398 HydrophobicContact CG2-CD1 3.94Å; V227-I398 HydrophobicContact CG2-CG1 4.03Å; V227-Y416 HydrophobicContact CG2-CD2 4.43Å; V227-Y416 HydrophobicContact CG2-CE2 3.96Å
228V96.9Very high97.9Very high9 Ų918 Ų186%0.0559%0.092CC..SBendtrans-112.216.3-176.9-600000114.3L201 Q394 T421 P424 I428 C429L201-V228 HydrophobicContact CD2-CG1 4.45Å; L201-V228 HydrophobicContact CD2-CG2 4.41Å; V228-Q394 CarbonylContact C-O 3.11Å; V228-T421 HydrophobicContact CG2-CG2 4.07Å; V228-P424 HydrophobicContact CG2-CB 3.85Å; V228-I428 HydrophobicContact CB-CB 4.46Å; V228-I428 HydrophobicContact CB-CG2 4.05Å; V228-I428 HydrophobicContact CG1-CB 4.12Å; V228-I428 HydrophobicContact CG1-CG2 3.83Å; V228-C429 WeakPolarHBondContact CG1-SG 3.29Å
229V96.9Very high97.9Very high47 Ų4717.4 Ų17.429%0.2859%0.089SC..SBendtrans-122.725.9-179.6-70.10000111.6V227 G233 Q394V227-V229 HydrophobicContact CG1-CG2 3.61Å; V229-G233 PolarHBondContact O-N 3.22Å; V229-Q394 PolarHBondContact N-O 2.84Å
230G97.3Very high97.9Very high9 Ų919.3 Ų19.39%0.09310%0.098CC..Hα-helixtrans70173-17700000113.8S232 G233 S234 Q394G230-S232 PolarHBondContact O-N 2.85Å; G230-G233 PolarHBondContact O-N 3.35Å; G230-S234 PolarHBondContact O-N 3.27Å; G230-Q394 VanDerWaalsContact CA-O 3.23Å; G230-Q394 WeakPolarHBondContact CA-O 3.36Å; G230-Q394 PolarHBondContact N-O 3.31Å
231T98.1Very high97.9Very high7 Ų719.3 Ų19.34%0.04310%0.098CC..Hα-helixtrans-65.6-21.3176.2-55.40000112.5G233 S234 N235 A350 H383 S384 S396T231-G233 VanDerWaalsContact C-N 3.27Å; T231-G233 PolarHBondContact O-N 2.97Å; T231-S234 WeakPolarHBondContact O-CB 3.13Å; T231-S234 PolarHBondContact O-N 2.88Å; T231-S234 VanDerWaalsContact O-N 3.12Å; T231-N235 WeakPolarHBondContact O-CB 3.42Å; T231-N235 PolarHBondContact O-N 3.49Å; T231-A350 HydrophobicContact CG2-CB 4.18Å; T231-H383 PolarHBondContact OG1-O 2.88Å; T231-S384 VanDerWaalsContact CB-OG 3.23Å; T231-S384 WeakPolarHBondContact CB-OG 3.33Å; T231-S384 WeakPolarHBondContact OG1-CA 3.3Å; T231-S384 WeakPolarHBondContact OG1-CB 3.32Å; T231-S384 PolarHBondContact OG1-N 2.94Å; T231-S384 PolarHBondContact OG1-OG 2.71Å; T231-S396 WeakPolarHBondContact CA-OG 3.47Å; T231-S396 PolarHBondContact N-OG 3.18Å; T231-S396 PolarHBondContact OG1-OG 3.09Å
232S97.3Very high97.9Very high39 Ų3919.2 Ų19.227%0.27310%0.097SC..Hα-helixtrans-57.8-39.3167.5-55.60000112.4G230 R236G230-S232 PolarHBondContact O-N 2.85Å; S232-R236 VanDerWaalsContact O-CG 3.29Å; S232-R236 WeakPolarHBondContact O-CG 3.42Å; S232-R236 PolarHBondContact O-N 3.42Å; S232-R236 PolarHBondContact O-NE 3.12Å
233G97.7Very high97.8Very high0 Ų016.5 Ų16.50%08%0.082CC..Hα-helixtrans-69-44.1170.600000112.2V229 G230 T231 N235 R236 T237V229-G233 PolarHBondContact O-N 3.22Å; G230-G233 PolarHBondContact O-N 3.35Å; T231-G233 VanDerWaalsContact C-N 3.27Å; T231-G233 PolarHBondContact O-N 2.97Å; G233-N235 PolarHBondContact O-N 2.72Å; G233-R236 PolarHBondContact O-N 2.93Å; G233-T237 WeakPolarHBondContact O-CB 3.18Å; G233-T237 PolarHBondContact O-N 3.12Å; G233-T237 PolarHBondContact O-OG1 3.09Å; G233-T237 VanDerWaalsContact O-OG1 3.07Å
234S98.4Very high97.7Very high0 Ų015.9 Ų15.90%09%0.09CC..Hα-helixtrans-55.7-48.1178.1-61.70000113.3V227 G230 T231 T237 I238 S396V227-S234 WeakPolarHBondContact CG2-OG 3.3Å; G230-S234 PolarHBondContact O-N 3.27Å; T231-S234 WeakPolarHBondContact O-CB 3.13Å; T231-S234 PolarHBondContact O-N 2.88Å; T231-S234 VanDerWaalsContact O-N 3.12Å; S234-T237 WeakPolarHBondContact O-CB 3.37Å; S234-T237 PolarHBondContact O-N 3.15Å; S234-I238 WeakPolarHBondContact O-CG1 3.27Å; S234-I238 PolarHBondContact O-N 2.76Å; S234-I238 VanDerWaalsContact O-N 3.08Å; S234-S396 PolarHBondContact OG-OG 2.8Å
235N98.5Very high97.4Very high1 Ų119.3 Ų19.31%0.00511%0.108CC..Hα-helixtrans-59.6-48.8178.5-75.5-12.5000111.2T231 G233 T237 I238 M239 S258 I259 H346 D348 T382T231-N235 WeakPolarHBondContact O-CB 3.42Å; T231-N235 PolarHBondContact O-N 3.49Å; G233-N235 PolarHBondContact O-N 2.72Å; N235-T237 PolarHBondContact O-N 3.31Å; N235-I238 PolarHBondContact O-N 3.24Å; N235-M239 VanDerWaalsContact O-CG 3.28Å; N235-M239 WeakPolarHBondContact O-CG 3.45Å; N235-M239 PolarHBondContact O-N 3.44Å; N235-S258 PolarHBondContact ND2-OG 2.94Å; N235-I259 HydrophobicContact CB-CD1 3.91Å; N235-H346 PolarHBondContact OD1-CE1 2.98Å; N235-H346 PolarHBondContact OD1-NE2 2.94Å; N235-D348 PolarHBondContact ND2-OD2 2.68Å; N235-T382 WeakPolarHBondContact OD1-CG2 3.33Å; N235-T382 PolarHBondContact OD1-OG1 3.38Å; N235-T382 VanDerWaalsContact OD1-OG1 3.08Å
236R98.1Very high97.1Very high61 Ų6122.3 Ų22.323%0.2312%0.124CC..Hα-helixtrans-64.1-39.6179-65.8178.5-62.8168.72.4112.5S232 G233 M239 Q240 Q261 L265 H419S232-R236 VanDerWaalsContact O-CG 3.29Å; S232-R236 WeakPolarHBondContact O-CG 3.42Å; S232-R236 PolarHBondContact O-N 3.42Å; S232-R236 PolarHBondContact O-NE 3.12Å; G233-R236 PolarHBondContact O-N 2.93Å; R236-M239 PolarHBondContact O-N 2.96Å; R236-Q240 WeakPolarHBondContact O-CB 3.47Å; R236-Q240 PolarHBondContact O-N 2.97Å; R236-Q261 HydrophobicContact CG-CB 4.37Å; R236-L265 HydrophobicContact CB-CD1 4.3Å; R236-L265 HydrophobicContact CG-CD1 4.16Å; R236-H419 WeakPolarHBondContact CB-NE2 3.42Å
237T98.3Very high97Very high2 Ų223.9 Ų23.91%0.01213%0.133CC..Hα-helixtrans-57.1-50.3174-66.60000111.9G233 S234 N235 M239 A241 I398 F412 A415 Y416 H419G233-T237 WeakPolarHBondContact O-CB 3.18Å; G233-T237 PolarHBondContact O-N 3.12Å; G233-T237 PolarHBondContact O-OG1 3.09Å; G233-T237 VanDerWaalsContact O-OG1 3.07Å; S234-T237 WeakPolarHBondContact O-CB 3.37Å; S234-T237 PolarHBondContact O-N 3.15Å; N235-T237 PolarHBondContact O-N 3.31Å; T237-M239 VanDerWaalsContact C-N 3.33Å; T237-M239 PolarHBondContact O-N 3.48Å; T237-A241 WeakPolarHBondContact O-CB 3.28Å; T237-A241 PolarHBondContact O-N 2.98Å; T237-I398 HydrophobicContact CG2-CD1 3.76Å; T237-F412 HydrophobicContact CG2-CE1 3.83Å; T237-F412 HydrophobicContact CG2-CZ 3.91Å; T237-A415 HydrophobicContact CG2-CB 4.39Å; T237-A415 WeakPolarHBondContact O-CB 3.36Å; T237-Y416 HydrophobicContact CG2-CD2 4.47Å; T237-H419 PolarHBondContact OG1-CD2 3.11Å
238I98.5Very high97Very high0 Ų023.7 Ų23.70%013%0.132CC..Hα-helixtrans-61-46.6178-66.5162.1000109.9S234 N235 A241 C242 Y316 F380 T382 I398 F412S234-I238 WeakPolarHBondContact O-CG1 3.27Å; S234-I238 PolarHBondContact O-N 2.76Å; S234-I238 VanDerWaalsContact O-N 3.08Å; N235-I238 PolarHBondContact O-N 3.24Å; I238-A241 WeakPolarHBondContact O-CB 3.2Å; I238-A241 PolarHBondContact O-N 2.74Å; I238-C242 WeakPolarHBondContact O-CB 3.19Å; I238-C242 PolarHBondContact O-N 3.26Å; I238-C242 PolarHBondContact O-SG 3.46Å; I238-Y316 HydrophobicContact CG2-CE2 3.89Å; I238-F380 HydrophobicContact CD1-CB 3.91Å; I238-F380 HydrophobicContact CD1-CD1 4.31Å; I238-F380 HydrophobicContact CD1-CG 4.34Å; I238-F380 HydrophobicContact CG1-CB 4.5Å; I238-F380 HydrophobicContact CG1-CD1 4.04Å; I238-F380 HydrophobicContact CG1-CG 4.4Å; I238-F380 HydrophobicContact CG2-CB 4.27Å; I238-F380 HydrophobicContact CG2-CD1 3.99Å; I238-F380 HydrophobicContact CG2-CD2 4.01Å; I238-F380 HydrophobicContact CG2-CE1 4.4Å; I238-F380 HydrophobicContact CG2-CE2 4.39Å; I238-F380 HydrophobicContact CG2-CG 3.82Å; I238-T382 HydrophobicContact CD1-CG2 3.26Å; I238-I398 HydrophobicContact CD1-CG1 4.39Å; I238-I398 HydrophobicContact CD1-CG2 3.82Å; I238-I398 HydrophobicContact CG1-CD1 4.34Å; I238-I398 HydrophobicContact CG1-CG2 3.91Å; I238-F412 HydrophobicContact CG1-CE2 4.26Å; I238-F412 HydrophobicContact CG1-CZ 4.06Å
239M98.4Very high97Very high0 Ų023.3 Ų23.30%013%0.129CC..Hα-helixtrans-61.9-50.3-177.3-68.9179.875.100111.4N235 R236 T237 A241 C242 M243 I259 L263 T266 Y316N235-M239 VanDerWaalsContact O-CG 3.28Å; N235-M239 WeakPolarHBondContact O-CG 3.45Å; N235-M239 PolarHBondContact O-N 3.44Å; R236-M239 PolarHBondContact O-N 2.96Å; T237-M239 VanDerWaalsContact C-N 3.33Å; T237-M239 PolarHBondContact O-N 3.48Å; M239-A241 PolarHBondContact O-N 3.34Å; M239-C242 PolarHBondContact O-N 3.3Å; M239-M243 HydrophobicContact CB-CE 3.82Å; M239-M243 HydrophobicContact CB-SD 4.15Å; M239-M243 HydrophobicContact CE-CE 4.04Å; M239-M243 HydrophobicContact CE-SD 3.85Å; M239-M243 HydrophobicContact CG-CE 3.85Å; M239-M243 VanDerWaalsContact O-CG 3.32Å; M239-M243 WeakPolarHBondContact O-CG 3.48Å; M239-M243 PolarHBondContact O-N 3.2Å; M239-I259 HydrophobicContact CE-CG2 4.15Å; M239-I259 WeakPolarHBondContact CE-O 3.45Å; M239-I259 HydrophobicContact SD-CB 4.46Å; M239-I259 HydrophobicContact SD-CD1 3.93Å; M239-I259 HydrophobicContact SD-CG2 4.11Å; M239-L263 HydrophobicContact CE-CD2 3.88Å; M239-L263 HydrophobicContact CE-CG 3.99Å; M239-T266 HydrophobicContact CB-CG2 4.33Å; M239-Y316 HydrophobicContact CG-CE1 4.29Å
240Q97.4Very high97.1Very high42 Ų4221 Ų2120%0.19612%0.116CC..Hα-helixtrans-61.4-30.2175.7-73.7-170.3-10.800113.3R236 T266 A415 H419R236-Q240 WeakPolarHBondContact O-CB 3.47Å; R236-Q240 PolarHBondContact O-N 2.97Å; Q240-T266 HydrophobicContact CB-CG2 4.46Å; Q240-T266 HydrophobicContact CG-CG2 3.93Å; Q240-A415 HydrophobicContact CB-CB 4.01Å; Q240-H419 VanDerWaalsContact CD-NE2 3.28Å; Q240-H419 PolarHBondContact OE1-NE2 3.43Å; Q240-H419 VanDerWaalsContact OE1-NE2 3.12Å
241A97.6Very high97.2Very high1 Ų120.6 Ų20.61%0.00811%0.111CC..Hα-helixtrans-71.8-35.8173.300000112.2T237 I238 M239 I407 R411 F412 A415T237-A241 WeakPolarHBondContact O-CB 3.28Å; T237-A241 PolarHBondContact O-N 2.98Å; I238-A241 WeakPolarHBondContact O-CB 3.2Å; I238-A241 PolarHBondContact O-N 2.74Å; M239-A241 PolarHBondContact O-N 3.34Å; A241-I407 HydrophobicContact CB-CD1 4.07Å; A241-R411 VanDerWaalsContact O-CZ 3.24Å; A241-R411 PolarHBondContact O-NE 2.92Å; A241-R411 PolarHBondContact O-NH2 2.92Å; A241-F412 HydrophobicContact CB-CD2 3.53Å; A241-F412 HydrophobicContact CB-CE2 3.87Å; A241-F412 HydrophobicContact CB-CG 4.26Å; A241-A415 HydrophobicContact CB-CB 3.94Å
242C97.4Very high97.1Very high1 Ų120.3 Ų20.31%0.00711%0.109CC..Hα-helixtrans-89.3-32.6-170.1-68.50000114.9I238 M239 Y316 R344 I407I238-C242 WeakPolarHBondContact O-CB 3.19Å; I238-C242 PolarHBondContact O-N 3.26Å; I238-C242 PolarHBondContact O-SG 3.46Å; M239-C242 PolarHBondContact O-N 3.3Å; C242-Y316 HydrophobicContact CB-CD2 3.92Å; C242-Y316 HydrophobicContact CB-CG 4.47Å; C242-R344 PolarHBondContact O-NH1 3.33Å; C242-I407 HydrophobicContact CB-CD1 4.36Å; C242-I407 WeakPolarHBondContact SG-CD1 3.45Å
243M95.8Very high97.1Very high7 Ų719 Ų193%0.03410%0.098CC..  trans-138160.3-168.276.2-159.65800112.6M239 D247 V249 T266 A268 Y316M239-M243 HydrophobicContact CB-CE 3.82Å; M239-M243 HydrophobicContact CB-SD 4.15Å; M239-M243 HydrophobicContact CE-CE 4.04Å; M239-M243 HydrophobicContact CE-SD 3.85Å; M239-M243 HydrophobicContact CG-CE 3.85Å; M239-M243 VanDerWaalsContact O-CG 3.32Å; M239-M243 WeakPolarHBondContact O-CG 3.48Å; M239-M243 PolarHBondContact O-N 3.2Å; M243-D247 VanDerWaalsContact CA-OD2 3.3Å; M243-D247 WeakPolarHBondContact CA-OD2 3.32Å; M243-D247 HydrophobicContact CB-CB 4.23Å; M243-V249 HydrophobicContact CB-CG1 4.18Å; M243-V249 HydrophobicContact CE-CG1 3.99Å; M243-V249 HydrophobicContact SD-CG1 3.83Å; M243-T266 HydrophobicContact CG-CG2 3.68Å; M243-T266 HydrophobicContact SD-CG2 4.16Å; M243-T266 PolarHBondContact SD-OG1 2.9Å; M243-A268 HydrophobicContact CB-CB 4.41Å; M243-A268 HydrophobicContact CG-CB 3.89Å; M243-A268 HydrophobicContact SD-CB 3.53Å; M243-A268 VanDerWaalsContact SD-CB 3.53Å; M243-Y316 HydrophobicContact CE-CD1 3.28Å; M243-Y316 HydrophobicContact CE-CD2 4Å; M243-Y316 HydrophobicContact CE-CE1 3.67Å; M243-Y316 HydrophobicContact CE-CE2 4.36Å; M243-Y316 HydrophobicContact CE-CG 3.42Å; M243-Y316 VanDerWaalsContact CE-CG 3.42Å
244T95Very high96.9Very high88 Ų8819 Ų1954%0.5410%0.098SC..  trans-133.5-178.5175.4-168.30000111.1N246 D247 T266T244-N246 PolarHBondContact O-N 3.13Å; T244-D247 PolarHBondContact N-OD2 2.67Å; T244-D247 WeakPolarHBondContact O-CB 3.15Å; T244-D247 PolarHBondContact O-N 3.38Å; T244-D247 VanDerWaalsContact O-N 3.11Å; T244-T266 CarbonylContact C-O 3.25Å; T244-T266 VanDerWaalsContact C-O 3.25Å
245D93.8Very high96.7Very high77 Ų7719.2 Ų19.241%0.41210%0.099SC..THydrogen-bonded Turntrans-50.6136.6176.5-171.551.5000110.2D247 T266 R667D245-D247 PolarHBondContact O-N 3.25Å; D245-T266 VanDerWaalsContact CA-O 3.22Å; D245-T266 WeakPolarHBondContact CA-O 3.41Å; D245-T266 PolarHBondContact N-O 3.41Å; D245-R667 VanDerWaalsContact CG-NH1 3.33Å; D245-R667 IonicContact OD1-CZ 3.53Å; D245-R667 IonicContact OD1-NH1 3.87Å; D245-R667 PolarHBondContact OD1-NH1 3.21Å
246N90.5Very high96.5Very high72 Ų7221.6 Ų21.639%0.38511%0.11SC..THydrogen-bonded Turntrans67.24.2-179.6-74-67.8000116.9T244 G267 K269 K309T244-N246 PolarHBondContact O-N 3.13Å; N246-G267 PolarHBondContact N-O 3.2Å; N246-K269 WeakPolarHBondContact OD1-CE 3.46Å; N246-K309 VanDerWaalsContact C-NZ 3.34Å; N246-K309 VanDerWaalsContact CA-NZ 3.28Å; N246-K309 PolarHBondContact O-NZ 3.08Å; N246-K309 PolarHBondContact OD1-NZ 2.99Å
247D97Very high96.3Very high35 Ų3521.3 Ų21.319%0.18711%0.111CC..  trans-66.9146.1167.5-78.4-22.1000111.3M243 T244 D245 A268 K269 S315M243-D247 VanDerWaalsContact CA-OD2 3.3Å; M243-D247 WeakPolarHBondContact CA-OD2 3.32Å; M243-D247 HydrophobicContact CB-CB 4.23Å; T244-D247 PolarHBondContact N-OD2 2.67Å; T244-D247 WeakPolarHBondContact O-CB 3.15Å; T244-D247 PolarHBondContact O-N 3.38Å; T244-D247 VanDerWaalsContact O-N 3.11Å; D245-D247 PolarHBondContact O-N 3.25Å; D247-A268 CarbonylContact O-C 3.14Å; D247-A268 WeakPolarHBondContact O-CA 3.4Å; D247-K269 PolarHBondContact O-N 3.3Å; D247-S315 WeakPolarHBondContact CB-OG 3.31Å; D247-S315 PolarHBondContact OD2-OG 3.11Å
248V97.7Very high96.2Very high0 Ų021.2 Ų21.20%011%0.111CC..EExtended strand (participates in β ladder)trans-88.1130168.4178.90000108.6K269 V271 I300 T306 K309 P314 S315V248-K269 WeakPolarHBondContact CA-O 3.22Å; V248-V271 HydrophobicContact CG1-CG2 4.13Å; V248-I300 HydrophobicContact CG1-CD1 3.94Å; V248-I300 HydrophobicContact CG1-CG1 3.87Å; V248-I300 HydrophobicContact CG1-CG2 4.49Å; V248-T306 HydrophobicContact CG1-CG2 4.27Å; V248-T306 HydrophobicContact CG2-CG2 4.15Å; V248-K309 HydrophobicContact CG2-CB 3.62Å; V248-K309 HydrophobicContact CG2-CD 3.54Å; V248-K309 HydrophobicContact CG2-CG 4.19Å; V248-P314 HydrophobicContact CG1-CG 4.39Å; V248-P314 CarbonylContact O-C 3.6Å; V248-P314 VanDerWaalsContact O-CA 3.24Å; V248-P314 WeakPolarHBondContact O-CA 3.45Å; V248-S315 PolarHBondContact O-N 3.48Å
249V98.2Very high96.1Very high0 Ų021.2 Ų21.20%011%0.111CC..EExtended strand (participates in β ladder)trans-131.7147-178.8-62.70000111.5M243 V251 L263 A268 K269 P270 V271 Y316M243-V249 HydrophobicContact CB-CG1 4.18Å; M243-V249 HydrophobicContact CE-CG1 3.99Å; M243-V249 HydrophobicContact SD-CG1 3.83Å; V249-V251 HydrophobicContact CG2-CG2 4.09Å; V249-L263 HydrophobicContact CG2-CD2 3.74Å; V249-A268 HydrophobicContact CB-CB 4.49Å; V249-A268 HydrophobicContact CG1-CB 3.84Å; V249-A268 HydrophobicContact CG2-CB 3.8Å; V249-K269 PolarHBondContact N-O 3.35Å; V249-K269 VanDerWaalsContact N-O 3.09Å; V249-P270 HydrophobicContact CG2-CB 4.37Å; V249-P270 CarbonylContact O-C 3.54Å; V249-P270 WeakPolarHBondContact O-CA 3.45Å; V249-V271 PolarHBondContact O-N 2.85Å; V249-Y316 HydrophobicContact CB-CD1 4.3Å; V249-Y316 HydrophobicContact CG1-CD1 4.41Å
250V98.2Very high96.1Very high0 Ų021.7 Ų21.70%011%0.113CC..EExtended strand (participates in β ladder)trans-102.9125.5178.5-177.60000109V271 M273 L296 P314 Y316 C317 V318 T341V250-V271 WeakPolarHBondContact CA-O 3.39Å; V250-M273 HydrophobicContact CG1-CE 3.83Å; V250-M273 HydrophobicContact CG1-CG 3.76Å; V250-M273 HydrophobicContact CG1-SD 3.76Å; V250-L296 HydrophobicContact CG1-CD1 4.31Å; V250-L296 HydrophobicContact CG1-CD2 3.66Å; V250-L296 HydrophobicContact CG2-CD1 4.37Å; V250-L296 HydrophobicContact CG2-CD2 4.29Å; V250-P314 HydrophobicContact CG2-CB 3.83Å; V250-P314 HydrophobicContact CG2-CG 3.83Å; V250-Y316 PolarHBondContact N-O 3.24Å; V250-C317 HydrophobicContact CB-CB 4.27Å; V250-C317 CarbonylContact O-C 3.56Å; V250-C317 VanDerWaalsContact O-CA 3.28Å; V250-C317 WeakPolarHBondContact O-CA 3.46Å; V250-V318 PolarHBondContact O-N 2.89Å; V250-T341 HydrophobicContact CG2-CG2 4.33Å
251V98.2Very high96Very high0 Ų022.6 Ų22.60%012%0.117CC..EExtended strand (participates in β ladder)trans-129.4130.8-171.7178.40000109.8V249 R253 C255 I259 L263 P270 V271 Y272 M273 V318V249-V251 HydrophobicContact CG2-CG2 4.09Å; V251-R253 PolarHBondContact O-N 3.2Å; V251-C255 HydrophobicContact CG1-CB 4.23Å; V251-I259 HydrophobicContact CG1-CG2 3.74Å; V251-L263 HydrophobicContact CG2-CD2 4.5Å; V251-P270 HydrophobicContact CG2-CB 4.29Å; V251-V271 PolarHBondContact N-O 2.81Å; V251-Y272 HydrophobicContact CB-CD1 3.95Å; V251-Y272 HydrophobicContact CB-CE1 4.07Å; V251-Y272 HydrophobicContact CG1-CD1 4.14Å; V251-Y272 HydrophobicContact CG1-CE1 4.08Å; V251-Y272 CarbonylContact O-C 3.56Å; V251-Y272 VanDerWaalsContact O-CA 3.22Å; V251-Y272 WeakPolarHBondContact O-CA 3.31Å; V251-M273 PolarHBondContact O-N 2.92Å; V251-V318 HydrophobicContact CB-CG1 4.15Å; V251-V318 HydrophobicContact CG1-CG1 3.94Å; V251-V318 HydrophobicContact CG2-CG1 4.05Å
252D97.6Very high96Very high0 Ų022.5 Ų22.50%012%0.116CC..EExtended strand (participates in β ladder)trans-60.1123.9165.2-178.7-3.6000110.3N254 C255 M273 I286 V318 T320D252-N254 PolarHBondContact O-N 3.08Å; D252-N254 WeakPolarHBondContact OD1-CA 3.46Å; D252-N254 WeakPolarHBondContact OD1-CB 3.49Å; D252-N254 PolarHBondContact OD1-N 2.83Å; D252-C255 WeakPolarHBondContact O-CB 3.18Å; D252-C255 PolarHBondContact O-N 3.31Å; D252-C255 PolarHBondContact O-SG 2.72Å; D252-C255 VanDerWaalsContact O-SG 3.34Å; D252-M273 HydrophobicContact CB-CE 4.3Å; D252-I286 HydrophobicContact CB-CD1 3.84Å; D252-I286 VanDerWaalsContact CG-CD1 3.41Å; D252-I286 WeakPolarHBondContact OD1-CD1 3.41Å; D252-V318 WeakPolarHBondContact CB-O 3.42Å; D252-V318 PolarHBondContact N-O 3.26Å; D252-T320 PolarHBondContact OD2-N 3.38Å; D252-T320 VanDerWaalsContact OD2-N 3.07Å
253R96.5Very high96.1Very high12 Ų1222.5 Ų22.55%0.04512%0.116CC..THydrogen-bonded Turntrans-63.7-20.7178.1-17257.2-179.1-162.53.2112.3V251 C255 M273 L659 M704 E709V251-R253 PolarHBondContact O-N 3.2Å; R253-C255 PolarHBondContact O-N 3.31Å; R253-M273 WeakPolarHBondContact CB-O 3.43Å; R253-M273 PolarHBondContact N-O 2.89Å; R253-L659 HydrophobicContact CG-CD2 3.89Å; R253-M704 PolarHBondContact NH2-O 2.92Å; R253-E709 IonicContact CZ-OE1 3.02Å; R253-E709 IonicContact CZ-OE2 3.96Å; R253-E709 IonicContact NH1-OE1 3.56Å; R253-E709 PolarHBondContact NH1-OE1 2.86Å; R253-E709 IonicContact NH1-OE2 2.61Å; R253-E709 VanDerWaalsContact NH2-CD 3.33Å; R253-E709 IonicContact NH2-OE1 2.84Å; R253-E709 PolarHBondContact NH2-OE1 2.61Å; R253-E709 IonicContact NH2-OE2 3.12Å; R253-E709 PolarHBondContact NH2-OE2 3.25Å
254N93.4Very high96.1Very high1 Ų123.9 Ų23.91%0.00512%0.123CC..THydrogen-bonded Turntrans-77.911.8172.5-158.346.6000114.3D252 P275 I283 I702D252-N254 PolarHBondContact O-N 3.08Å; D252-N254 WeakPolarHBondContact OD1-CA 3.46Å; D252-N254 WeakPolarHBondContact OD1-CB 3.49Å; D252-N254 PolarHBondContact OD1-N 2.83Å; N254-P275 HydrophobicContact CB-CB 4.41Å; N254-P275 HydrophobicContact CB-CG 4Å; N254-I283 WeakPolarHBondContact ND2-CG2 3.49Å; N254-I283 WeakPolarHBondContact OD1-CG2 3.43Å; N254-I702 WeakPolarHBondContact OD1-CD1 3.28Å
255C93.5Very high96.2Very high3 Ų323.4 Ų23.42%0.0212%0.117CC..  trans-67.6145.3-175.464.50000112.7V251 D252 R253 I259 P703V251-C255 HydrophobicContact CG1-CB 4.23Å; D252-C255 WeakPolarHBondContact O-CB 3.18Å; D252-C255 PolarHBondContact O-N 3.31Å; D252-C255 PolarHBondContact O-SG 2.72Å; D252-C255 VanDerWaalsContact O-SG 3.34Å; R253-C255 PolarHBondContact O-N 3.31Å; C255-I259 HydrophobicContact CB-CB 3.75Å; C255-I259 HydrophobicContact CB-CG1 3.77Å; C255-I259 HydrophobicContact CB-CG2 4.01Å; C255-P703 WeakPolarHBondContact O-CD 3.39Å
256H94.5Very high96.4Very high51 Ų5120 Ų2024%0.23610%0.099CC..  trans-63.8149168.9179.2-108000111.1S258 I259H256-S258 PolarHBondContact ND1-N 3.27Å; H256-S258 PolarHBondContact ND1-OG 3.23Å; H256-S258 PolarHBondContact O-N 3.38Å; H256-I259 PolarHBondContact O-N 2.95Å
257K93.9Very high96.7Very high55 Ų5516.8 Ų16.824%0.2398%0.082CC..Hα-helixtrans-48.8-23.1-179.769-172.8179.3-1690115.8I259 E260 Q261 I696 G701 E740K257-I259 VanDerWaalsContact C-N 3.27Å; K257-I259 PolarHBondContact O-N 2.93Å; K257-E260 WeakPolarHBondContact O-CB 3.49Å; K257-E260 PolarHBondContact O-N 2.92Å; K257-Q261 WeakPolarHBondContact O-CG 3.36Å; K257-Q261 PolarHBondContact O-N 2.76Å; K257-I696 HydrophobicContact CB-CD1 3.88Å; K257-I696 HydrophobicContact CD-CD1 4.01Å; K257-G701 PolarHBondContact N-O 3.28Å; K257-E740 IonicContact NZ-OE1 3.06Å; K257-E740 PolarHBondContact NZ-OE1 3.16Å; K257-E740 IonicContact NZ-OE2 2.69Å; K257-E740 PolarHBondContact NZ-OE2 3.16Å
258S96.5Very high96.7Very high1 Ų115.1 Ų15.11%0.0077%0.073CC..Hα-helixtrans-63-27.2173.254.90000114.9N235 H256 G262N235-S258 PolarHBondContact ND2-OG 2.94Å; H256-S258 PolarHBondContact ND1-N 3.27Å; H256-S258 PolarHBondContact ND1-OG 3.23Å; H256-S258 PolarHBondContact O-N 3.38Å; S258-G262 PolarHBondContact O-N 3.28Å; S258-G262 VanDerWaalsContact O-N 3.08Å
259I97.8Very high96.7Very high0 Ų016.7 Ų16.70%08%0.08CC..Hα-helixtrans-72.5-42176.5-62.4-62.3000109.9N235 M239 V251 C255 H256 K257 Q261 G262 L263 V318N235-I259 HydrophobicContact CB-CD1 3.91Å; M239-I259 HydrophobicContact CE-CG2 4.15Å; M239-I259 WeakPolarHBondContact CE-O 3.45Å; M239-I259 HydrophobicContact SD-CB 4.46Å; M239-I259 HydrophobicContact SD-CD1 3.93Å; M239-I259 HydrophobicContact SD-CG2 4.11Å; V251-I259 HydrophobicContact CG1-CG2 3.74Å; C255-I259 HydrophobicContact CB-CB 3.75Å; C255-I259 HydrophobicContact CB-CG1 3.77Å; C255-I259 HydrophobicContact CB-CG2 4.01Å; H256-I259 PolarHBondContact O-N 2.95Å; K257-I259 VanDerWaalsContact C-N 3.27Å; K257-I259 PolarHBondContact O-N 2.93Å; I259-Q261 VanDerWaalsContact C-N 3.34Å; I259-Q261 PolarHBondContact O-N 2.74Å; I259-G262 WeakPolarHBondContact O-CA 3.49Å; I259-G262 PolarHBondContact O-N 2.88Å; I259-L263 PolarHBondContact O-N 3.11Å; I259-V318 HydrophobicContact CD1-CG2 4.09Å; I259-V318 HydrophobicContact CG2-CG1 4.15Å
260E96.9Very high96.6Very high9 Ų916.8 Ų16.84%0.0428%0.081CC..Hα-helixtrans-58.3-45.2170.7-177.3-162.2-149.700111.5K257 G262 L263 M264 P666 S694 L706 S707K257-E260 WeakPolarHBondContact O-CB 3.49Å; K257-E260 PolarHBondContact O-N 2.92Å; E260-G262 PolarHBondContact O-N 3.45Å; E260-L263 CarbonylContact O-C 3.58Å; E260-L263 WeakPolarHBondContact O-CA 3.06Å; E260-L263 WeakPolarHBondContact O-CB 3.49Å; E260-L263 PolarHBondContact O-N 3.42Å; E260-M264 VanDerWaalsContact CD-CE 3.46Å; E260-M264 HydrophobicContact CG-CE 3.76Å; E260-M264 WeakPolarHBondContact O-CG 3.44Å; E260-M264 PolarHBondContact O-N 3.1Å; E260-P666 HydrophobicContact CG-CB 4.41Å; E260-S694 PolarHBondContact OE1-OG 2.93Å; E260-S694 WeakPolarHBondContact OE2-CB 3.22Å; E260-S694 PolarHBondContact OE2-OG 3.49Å; E260-L706 HydrophobicContact CB-CD2 3.86Å; E260-L706 HydrophobicContact CG-CD2 3.8Å; E260-S707 WeakPolarHBondContact OE1-CB 3.24Å; E260-S707 PolarHBondContact OE1-N 3.25Å; E260-S707 PolarHBondContact OE1-OG 3.49Å
261Q96.8Very high96.5Very high61 Ų6117 Ų1729%0.2858%0.083SC..Hα-helixtrans-57.4-36.7174.2-67.1171.2300111.9R236 K257 I259 M264 L265R236-Q261 HydrophobicContact CG-CB 4.37Å; K257-Q261 WeakPolarHBondContact O-CG 3.36Å; K257-Q261 PolarHBondContact O-N 2.76Å; I259-Q261 VanDerWaalsContact C-N 3.34Å; I259-Q261 PolarHBondContact O-N 2.74Å; Q261-M264 PolarHBondContact O-N 3.35Å; Q261-L265 WeakPolarHBondContact O-CB 3.26Å; Q261-L265 VanDerWaalsContact O-CG 3.24Å; Q261-L265 WeakPolarHBondContact O-CG 3.47Å; Q261-L265 PolarHBondContact O-N 2.9Å
262G97.7Very high96.5Very high0 Ų017.8 Ų17.80%09%0.085CC..Hα-helixtrans-61.5-44.7171.100000112.5S258 I259 E260 M264 L265 T266S258-G262 PolarHBondContact O-N 3.28Å; S258-G262 VanDerWaalsContact O-N 3.08Å; I259-G262 WeakPolarHBondContact O-CA 3.49Å; I259-G262 PolarHBondContact O-N 2.88Å; E260-G262 PolarHBondContact O-N 3.45Å; G262-M264 PolarHBondContact O-N 2.78Å; G262-L265 PolarHBondContact O-N 3.04Å; G262-T266 WeakPolarHBondContact O-CG2 3.43Å; G262-T266 PolarHBondContact O-N 3.06Å; G262-T266 PolarHBondContact O-OG1 3.28Å
263L97.6Very high96.5Very high1 Ų117.8 Ų17.81%0.0059%0.085CC..Hα-helixtrans-61.6-40.6175.1-63172.4000112.4M239 V249 V251 I259 E260 L265 G267 A268 P270 P666M239-L263 HydrophobicContact CE-CD2 3.88Å; M239-L263 HydrophobicContact CE-CG 3.99Å; V249-L263 HydrophobicContact CG2-CD2 3.74Å; V251-L263 HydrophobicContact CG2-CD2 4.5Å; I259-L263 PolarHBondContact O-N 3.11Å; E260-L263 CarbonylContact O-C 3.58Å; E260-L263 WeakPolarHBondContact O-CA 3.06Å; E260-L263 WeakPolarHBondContact O-CB 3.49Å; E260-L263 PolarHBondContact O-N 3.42Å; L263-L265 VanDerWaalsContact C-N 3.34Å; L263-L265 PolarHBondContact O-N 3.33Å; L263-G267 WeakPolarHBondContact O-CA 3.37Å; L263-G267 PolarHBondContact O-N 2.87Å; L263-A268 HydrophobicContact CD2-CB 4.24Å; L263-P270 HydrophobicContact CD1-CB 3.87Å; L263-P270 HydrophobicContact CD1-CG 3.97Å; L263-P270 HydrophobicContact CD2-CB 4.17Å; L263-P666 HydrophobicContact CB-CB 4.23Å; L263-P666 HydrophobicContact CB-CG 4.06Å; L263-P666 HydrophobicContact CD1-CG 4.28Å
264M97.4Very high96.4Very high35 Ų3518.5 Ų18.517%0.1729%0.091CC..Hα-helixtrans-59.5-46.7173.8-65.4167.7177.800110.8E260 Q261 G262 P666 R667 S707E260-M264 VanDerWaalsContact CD-CE 3.46Å; E260-M264 HydrophobicContact CG-CE 3.76Å; E260-M264 WeakPolarHBondContact O-CG 3.44Å; E260-M264 PolarHBondContact O-N 3.1Å; Q261-M264 PolarHBondContact O-N 3.35Å; G262-M264 PolarHBondContact O-N 2.78Å; M264-P666 HydrophobicContact CG-CB 3.79Å; M264-R667 WeakPolarHBondContact O-CB 3.21Å; M264-R667 PolarHBondContact O-NE 3.49Å; M264-S707 WeakPolarHBondContact CE-OG 3.49Å
265L97.3Very high96.5Very high78 Ų7819 Ų1941%0.40810%0.095SC..Hα-helixtrans-70.8-35.7-177.5-72.2171.7000113.6R236 Q261 G262 L263 R667R236-L265 HydrophobicContact CB-CD1 4.3Å; R236-L265 HydrophobicContact CG-CD1 4.16Å; Q261-L265 WeakPolarHBondContact O-CB 3.26Å; Q261-L265 VanDerWaalsContact O-CG 3.24Å; Q261-L265 WeakPolarHBondContact O-CG 3.47Å; Q261-L265 PolarHBondContact O-N 2.9Å; G262-L265 PolarHBondContact O-N 3.04Å; L263-L265 VanDerWaalsContact C-N 3.34Å; L263-L265 PolarHBondContact O-N 3.33Å; L265-R667 VanDerWaalsContact C-NH2 3.31Å; L265-R667 PolarHBondContact O-NH2 3.47Å
266T97.4Very high96.6Very high7 Ų719.6 Ų19.64%0.04310%0.098CC..Hα-helixtrans-95-25.9-177.1640000113.8M239 Q240 M243 T244 D245 G262 A268 R667M239-T266 HydrophobicContact CB-CG2 4.33Å; Q240-T266 HydrophobicContact CB-CG2 4.46Å; Q240-T266 HydrophobicContact CG-CG2 3.93Å; M243-T266 HydrophobicContact CG-CG2 3.68Å; M243-T266 HydrophobicContact SD-CG2 4.16Å; M243-T266 PolarHBondContact SD-OG1 2.9Å; T244-T266 CarbonylContact C-O 3.25Å; T244-T266 VanDerWaalsContact C-O 3.25Å; D245-T266 VanDerWaalsContact CA-O 3.22Å; D245-T266 WeakPolarHBondContact CA-O 3.41Å; D245-T266 PolarHBondContact N-O 3.41Å; G262-T266 WeakPolarHBondContact O-CG2 3.43Å; G262-T266 PolarHBondContact O-N 3.06Å; G262-T266 PolarHBondContact O-OG1 3.28Å; T266-A268 PolarHBondContact O-N 3.41Å; T266-A268 PolarHBondContact OG1-N 3.43Å; T266-R667 VanDerWaalsContact CA-NH2 3.33Å; T266-R667 VanDerWaalsContact O-CZ 3.29Å; T266-R667 PolarHBondContact O-NH1 3.46Å; T266-R667 PolarHBondContact O-NH2 2.86Å
267G96.8Very high96.6Very high3 Ų319.3 Ų19.33%0.03110%0.095CC..  trans68.317.6-17700000112.9N246 L263 R667N246-G267 PolarHBondContact N-O 3.2Å; L263-G267 WeakPolarHBondContact O-CA 3.37Å; L263-G267 PolarHBondContact O-N 2.87Å; G267-R667 VanDerWaalsContact CA-NE 3.28Å
268A97.4Very high96.6Very high0 Ų016.8 Ų16.80%09%0.085CC..  trans-61147.5169.200000109.4M243 D247 V249 L263 T266 P270M243-A268 HydrophobicContact CB-CB 4.41Å; M243-A268 HydrophobicContact CG-CB 3.89Å; M243-A268 HydrophobicContact SD-CB 3.53Å; M243-A268 VanDerWaalsContact SD-CB 3.53Å; D247-A268 CarbonylContact O-C 3.14Å; D247-A268 WeakPolarHBondContact O-CA 3.4Å; V249-A268 HydrophobicContact CB-CB 4.49Å; V249-A268 HydrophobicContact CG1-CB 3.84Å; V249-A268 HydrophobicContact CG2-CB 3.8Å; L263-A268 HydrophobicContact CD2-CB 4.24Å; T266-A268 PolarHBondContact O-N 3.41Å; T266-A268 PolarHBondContact OG1-N 3.43Å; A268-P270 WeakPolarHBondContact O-CD 3.46Å
269K97Very high96.5Very high33 Ų3318.6 Ų18.614%0.1439%0.091CC..EExtended strand (participates in β ladder)trans-97.1110.6179.9-58.8-159.1-180176.90108.8N246 D247 V248 V249 L305 T306 D308 T665N246-K269 WeakPolarHBondContact OD1-CE 3.46Å; D247-K269 PolarHBondContact O-N 3.3Å; V248-K269 WeakPolarHBondContact CA-O 3.22Å; V249-K269 PolarHBondContact N-O 3.35Å; V249-K269 VanDerWaalsContact N-O 3.09Å; K269-L305 HydrophobicContact CD-CB 4.38Å; K269-L305 WeakPolarHBondContact CD-O 3.36Å; K269-L305 WeakPolarHBondContact CE-O 3.46Å; K269-L305 PolarHBondContact NZ-O 3.5Å; K269-T306 HydrophobicContact CB-CG2 3.56Å; K269-T306 HydrophobicContact CD-CG2 4.45Å; K269-D308 IonicContact NZ-OD1 3.68Å; K269-D308 IonicContact NZ-OD2 3.82Å; K269-T665 HydrophobicContact CG-CG2 4.25Å
270P96.8Very high96.3Very high2 Ų219.6 Ų19.61%0.01310%0.095CC..EExtended strand (participates in β ladder)trans-81.1149.8-173.133.3-36.8000112.4V249 V251 L263 A268 Y272 L305V249-P270 HydrophobicContact CG2-CB 4.37Å; V249-P270 CarbonylContact O-C 3.54Å; V249-P270 WeakPolarHBondContact O-CA 3.45Å; V251-P270 HydrophobicContact CG2-CB 4.29Å; L263-P270 HydrophobicContact CD1-CB 3.87Å; L263-P270 HydrophobicContact CD1-CG 3.97Å; L263-P270 HydrophobicContact CD2-CB 4.17Å; A268-P270 WeakPolarHBondContact O-CD 3.46Å; P270-Y272 HydrophobicContact CB-CE1 3.9Å; P270-Y272 HydrophobicContact CB-CE2 4.22Å; P270-Y272 HydrophobicContact CG-CE1 4.37Å; P270-Y272 HydrophobicContact CG-CE2 4.08Å; P270-Y272 WeakPolarHBondContact CG-OH 3.44Å; P270-L305 HydrophobicContact CG-CD1 4.49Å
271V96.5Very high96.1Very high6 Ų619.2 Ų19.24%0.0369%0.094CC..EExtended strand (participates in β ladder)trans-128.1133.6162.7-173.50000107.6V248 V249 V250 V251 K299 I300 T306V248-V271 HydrophobicContact CG1-CG2 4.13Å; V249-V271 PolarHBondContact O-N 2.85Å; V250-V271 WeakPolarHBondContact CA-O 3.39Å; V251-V271 PolarHBondContact N-O 2.81Å; V271-K299 HydrophobicContact CG1-CB 3.33Å; V271-K299 HydrophobicContact CG1-CD 4.25Å; V271-K299 HydrophobicContact CG1-CG 4.43Å; V271-I300 HydrophobicContact CB-CG1 4.42Å; V271-I300 HydrophobicContact CG1-CG1 4.43Å; V271-I300 HydrophobicContact CG2-CG1 3.73Å; V271-T306 HydrophobicContact CG2-CG2 3.85Å
272Y97.1Very high96Very high15 Ų1516.3 Ų16.36%0.0598%0.08CC..EExtended strand (participates in β ladder)trans-102.4136.9-166.4-58.8-74.1000114V251 P270 K299 L659 L706V251-Y272 HydrophobicContact CB-CD1 3.95Å; V251-Y272 HydrophobicContact CB-CE1 4.07Å; V251-Y272 HydrophobicContact CG1-CD1 4.14Å; V251-Y272 HydrophobicContact CG1-CE1 4.08Å; V251-Y272 CarbonylContact O-C 3.56Å; V251-Y272 VanDerWaalsContact O-CA 3.22Å; V251-Y272 WeakPolarHBondContact O-CA 3.31Å; P270-Y272 HydrophobicContact CB-CE1 3.9Å; P270-Y272 HydrophobicContact CB-CE2 4.22Å; P270-Y272 HydrophobicContact CG-CE1 4.37Å; P270-Y272 HydrophobicContact CG-CE2 4.08Å; P270-Y272 WeakPolarHBondContact CG-OH 3.44Å; Y272-K299 PolarHBondContact O-NZ 3.36Å; Y272-L659 HydrophobicContact CD2-CD2 4.25Å; Y272-L659 HydrophobicContact CG-CD2 4.32Å; Y272-L706 HydrophobicContact CE1-CD1 3.61Å; Y272-L706 HydrophobicContact CE2-CD1 4.29Å; Y272-L706 WeakPolarHBondContact OH-CD1 3.33Å
273M97.2Very high95.9Very high0 Ų016.3 Ų16.30%08%0.08CC..EExtended strand (participates in β ladder)trans-87.7129.2160.9-63.8173.8-62.500108.3V250 V251 D252 R253 I286 M291 L296 V318 V319 L338V250-M273 HydrophobicContact CG1-CE 3.83Å; V250-M273 HydrophobicContact CG1-CG 3.76Å; V250-M273 HydrophobicContact CG1-SD 3.76Å; V251-M273 PolarHBondContact O-N 2.92Å; D252-M273 HydrophobicContact CB-CE 4.3Å; R253-M273 WeakPolarHBondContact CB-O 3.43Å; R253-M273 PolarHBondContact N-O 2.89Å; M273-I286 HydrophobicContact CB-CD1 3.72Å; M273-I286 HydrophobicContact CB-CG1 4.16Å; M273-I286 HydrophobicContact CB-CG2 4Å; M273-I286 HydrophobicContact CE-CD1 4Å; M273-I286 HydrophobicContact SD-CD1 4.33Å; M273-M291 HydrophobicContact SD-CG 3.95Å; M273-L296 HydrophobicContact CG-CD2 4.05Å; M273-V318 WeakPolarHBondContact CE-O 3.31Å; M273-V319 HydrophobicContact CE-CG2 3.66Å; M273-L338 HydrophobicContact SD-CD2 3.97Å
274V95.8Very high95.8Very high27 Ų2716.2 Ų16.216%0.1648%0.08CC..PPolyproline II helixtrans-97.5119.1-176.4-175.60000108.8E290 L659V274-E290 PolarHBondContact N-OE2 3.02Å; V274-L659 HydrophobicContact CG2-CD1 3.85Å; V274-L659 HydrophobicContact CG2-CD2 3.93Å; V274-L659 HydrophobicContact CG2-CG 3.75Å
275P95.2Very high95.7Very high13 Ų1314.6 Ų14.68%0.0847%0.072CC..PPolyproline II helixtrans-71.1159175.435.1-41000110.8N254 I283 I286N254-P275 HydrophobicContact CB-CB 4.41Å; N254-P275 HydrophobicContact CB-CG 4Å; P275-I283 HydrophobicContact CB-CG2 4.42Å; P275-I286 HydrophobicContact CB-CG1 4.23Å
276S95.1Very high95.7Very high14 Ų1410.9 Ų10.910%0.0985%0.052CC..PPolyproline II helixtrans-77.1161.1167600000112G284 P285 Y287S276-G284 WeakPolarHBondContact O-CA 3.29Å; S276-G284 PolarHBondContact O-N 3.36Å; S276-G284 WeakPolarHBondContact OG-CA 3.49Å; S276-P285 WeakPolarHBondContact CB-O 3.45Å; S276-P285 PolarHBondContact N-O 3.25Å; S276-P285 VanDerWaalsContact OG-CD 3.29Å; S276-P285 WeakPolarHBondContact OG-CD 3.37Å; S276-P285 PolarHBondContact OG-O 2.76Å; S276-Y287 VanDerWaalsContact CB-CE2 3.49Å
277R94.1Very high95.7Very high45 Ų4512.9 Ų12.917%0.176%0.059CC..BIsolated β-bridgetrans-138.4149.8168.9-70.5-177.1-179.9-90.70.4109.5G281 I282 Y656R277-G281 PolarHBondContact NH1-O 2.99Å; R277-I282 WeakPolarHBondContact CA-O 3.12Å; R277-Y656 VanDerWaalsContact NH2-CD1 3.27Å
278N94.9Very high95.7Very high3 Ų313.7 Ų13.72%0.0166%0.064CC..  trans-100.3-179.617574.711.9000112Y280 G281 I282 H520 F522 N653N278-Y280 PolarHBondContact O-N 3.09Å; N278-Y280 VanDerWaalsContact O-N 3.12Å; N278-Y280 PolarHBondContact OD1-N 2.87Å; N278-G281 PolarHBondContact O-N 2.69Å; N278-G281 PolarHBondContact OD1-N 3.28Å; N278-I282 PolarHBondContact N-O 3.48Å; N278-I282 VanDerWaalsContact N-O 3.17Å; N278-I282 WeakPolarHBondContact OD1-CB 3.34Å; N278-I282 PolarHBondContact OD1-N 2.85Å; N278-I282 VanDerWaalsContact OD1-N 3.14Å; N278-H520 PolarHBondContact ND2-O 3.23Å; N278-F522 HydrophobicContact CB-CD1 3.89Å; N278-F522 HydrophobicContact CB-CE1 3.68Å; N278-F522 HydrophobicContact CB-CZ 4.24Å; N278-N653 PolarHBondContact O-ND2 2.96Å
279R94Very high95.7Very high39 Ų3919.2 Ų19.215%0.1479%0.09CC..THydrogen-bonded Turntrans-57.4-23.3-18064.5-177.2-176.5-109.90.5115.5G281 M544 G545 E546R279-G281 VanDerWaalsContact C-N 3.35Å; R279-M544 HydrophobicContact CB-SD 4.46Å; R279-M544 HydrophobicContact CG-CG 4.24Å; R279-G545 WeakPolarHBondContact CD-O 3.36Å; R279-G545 PolarHBondContact NE-O 3.2Å; R279-E546 PolarHBondContact NH1-O 3.43Å
280Y93.9Very high95.6Very high20 Ų2019.6 Ų19.68%0.0789%0.092CC..THydrogen-bonded Turntrans-90.30.5178.8-57.3-70.8000113.2N278 I282 L540 M544 T575 F577N278-Y280 PolarHBondContact O-N 3.09Å; N278-Y280 VanDerWaalsContact O-N 3.12Å; N278-Y280 PolarHBondContact OD1-N 2.87Å; Y280-I282 HydrophobicContact CD2-CD1 4.35Å; Y280-I282 PolarHBondContact O-N 3.4Å; Y280-L540 HydrophobicContact CD1-CD2 4.15Å; Y280-L540 HydrophobicContact CD2-CD2 4.19Å; Y280-L540 HydrophobicContact CE1-CD1 4.29Å; Y280-L540 HydrophobicContact CE1-CD2 4.17Å; Y280-L540 HydrophobicContact CE2-CD1 3.83Å; Y280-L540 HydrophobicContact CE2-CD2 4.22Å; Y280-L540 HydrophobicContact CG-CD2 4.15Å; Y280-M544 HydrophobicContact CD1-CB 4.3Å; Y280-M544 HydrophobicContact CD1-CG 4.01Å; Y280-M544 HydrophobicContact CE1-CB 3.76Å; Y280-M544 HydrophobicContact CE1-CG 3.64Å; Y280-T575 WeakPolarHBondContact O-CB 3.46Å; Y280-T575 WeakPolarHBondContact O-CG2 3.42Å; Y280-T575 PolarHBondContact O-OG1 2.66Å; Y280-F577 HydrophobicContact CD1-CB 4.31Å
281G92.8Very high95.7Very high1 Ų119.5 Ų19.51%0.019%0.091CC..  trans74.314.3-171.800000113.6R277 N278 R279 R573R277-G281 PolarHBondContact NH1-O 2.99Å; N278-G281 PolarHBondContact O-N 2.69Å; N278-G281 PolarHBondContact OD1-N 3.28Å; R279-G281 VanDerWaalsContact C-N 3.35Å; G281-R573 PolarHBondContact O-NH2 2.76Å
282I95Very high95.7Very high0 Ų021.8 Ų21.80%010%0.102CC..  trans-70.1135.4173-63.8171.7000108.6R277 N278 Y280 G284 D325 W480 F522 Q578R277-I282 WeakPolarHBondContact CA-O 3.12Å; N278-I282 PolarHBondContact N-O 3.48Å; N278-I282 VanDerWaalsContact N-O 3.17Å; N278-I282 WeakPolarHBondContact OD1-CB 3.34Å; N278-I282 PolarHBondContact OD1-N 2.85Å; N278-I282 VanDerWaalsContact OD1-N 3.14Å; Y280-I282 HydrophobicContact CD2-CD1 4.35Å; Y280-I282 PolarHBondContact O-N 3.4Å; I282-G284 PolarHBondContact O-N 2.83Å; I282-D325 HydrophobicContact CG2-CB 3.64Å; I282-W480 HydrophobicContact CD1-CD2 3.67Å; I282-W480 HydrophobicContact CD1-CE3 3.96Å; I282-W480 HydrophobicContact CD1-CG 4.16Å; I282-W480 HydrophobicContact CD1-CH2 4.26Å; I282-W480 HydrophobicContact CD1-CZ2 3.99Å; I282-W480 HydrophobicContact CD1-CZ3 4.23Å; I282-W480 HydrophobicContact CG2-CH2 3.64Å; I282-W480 HydrophobicContact CG2-CZ2 4.08Å; I282-W480 HydrophobicContact CG2-CZ3 3.98Å; I282-F522 HydrophobicContact CG2-CZ 4.15Å; I282-Q578 HydrophobicContact CD1-CG 4.14Å; I282-Q578 HydrophobicContact CG1-CG 4.29Å
283I94.9Very high95.7Very high0 Ų022.5 Ų22.50%011%0.108CC..BIsolated β-bridgetrans-80.1117.3-179-57155.5000109.6N254 P275 T323 D325 V327 P700 I702N254-I283 WeakPolarHBondContact ND2-CG2 3.49Å; N254-I283 WeakPolarHBondContact OD1-CG2 3.43Å; P275-I283 HydrophobicContact CB-CG2 4.42Å; I283-T323 HydrophobicContact CG2-CG2 4.06Å; I283-T323 PolarHBondContact O-OG1 3.21Å; I283-D325 PolarHBondContact N-OD2 3.41Å; I283-V327 WeakPolarHBondContact O-CG2 3.46Å; I283-P700 HydrophobicContact CD1-CG 4.28Å; I283-I702 HydrophobicContact CD1-CD1 3.62Å
284G95.1Very high95.7Very high0 Ų029 Ų290%014%0.139CC..  trans-91.4-173.8175.400000113.3S276 I282S276-G284 WeakPolarHBondContact O-CA 3.29Å; S276-G284 PolarHBondContact O-N 3.36Å; S276-G284 WeakPolarHBondContact OG-CA 3.49Å; I282-G284 PolarHBondContact O-N 2.83Å
285P95.9Very high95.8Very high0 Ų029.7 Ų29.70%014%0.143CC..PPolyproline II helixtrans-76.3157.4178.734-34.8000111.2S276 V327 Y329 I525 S530S276-P285 WeakPolarHBondContact CB-O 3.45Å; S276-P285 PolarHBondContact N-O 3.25Å; S276-P285 VanDerWaalsContact OG-CD 3.29Å; S276-P285 WeakPolarHBondContact OG-CD 3.37Å; S276-P285 PolarHBondContact OG-O 2.76Å; P285-V327 HydrophobicContact CB-CG1 4.41Å; P285-V327 HydrophobicContact CG-CG1 4.49Å; P285-Y329 WeakPolarHBondContact CA-OH 3.13Å; P285-Y329 HydrophobicContact CB-CD1 4.02Å; P285-Y329 HydrophobicContact CB-CE1 3.48Å; P285-Y329 VanDerWaalsContact CB-CE1 3.48Å; P285-I525 HydrophobicContact CG-CD1 4.09Å; P285-S530 VanDerWaalsContact CB-OG 3.31Å; P285-S530 WeakPolarHBondContact CB-OG 3.48Å; P285-S530 WeakPolarHBondContact CG-OG 3.27Å
286I97.2Very high95.9Very high0 Ų029 Ų290%014%0.139CC..PPolyproline II helixtrans-64.8127.2153.7-64.6161000107.7D252 M273 P275 E290 M291 V319 Y329 W529D252-I286 HydrophobicContact CB-CD1 3.84Å; D252-I286 VanDerWaalsContact CG-CD1 3.41Å; D252-I286 WeakPolarHBondContact OD1-CD1 3.41Å; M273-I286 HydrophobicContact CB-CD1 3.72Å; M273-I286 HydrophobicContact CB-CG1 4.16Å; M273-I286 HydrophobicContact CB-CG2 4Å; M273-I286 HydrophobicContact CE-CD1 4Å; M273-I286 HydrophobicContact SD-CD1 4.33Å; P275-I286 HydrophobicContact CB-CG1 4.23Å; I286-E290 HydrophobicContact CG2-CB 3.44Å; I286-E290 VanDerWaalsContact CG2-CB 3.44Å; I286-E290 HydrophobicContact CG2-CG 4.23Å; I286-M291 HydrophobicContact CB-CE 3.84Å; I286-M291 HydrophobicContact CD1-CE 4.27Å; I286-M291 HydrophobicContact CG2-CE 3.78Å; I286-M291 HydrophobicContact CG2-CG 4.02Å; I286-V319 HydrophobicContact CD1-CG1 4.37Å; I286-Y329 HydrophobicContact CB-CE1 4.09Å; I286-Y329 WeakPolarHBondContact CG1-OH 3.27Å; I286-Y329 PolarHBondContact N-OH 2.85Å; I286-W529 WeakPolarHBondContact O-CZ2 3.47Å; I286-W529 PolarHBondContact O-NE1 3.4Å
287Y96.7Very high95.9Very high49 Ų4931 Ų3119%0.19215%0.147CC..PPolyproline II helixtrans-75.1153.7177.1-67-64.9000112.3S276 Q289 E290 K523 I525S276-Y287 VanDerWaalsContact CB-CE2 3.49Å; Y287-Q289 PolarHBondContact O-N 3.14Å; Y287-E290 WeakPolarHBondContact O-CB 3.41Å; Y287-E290 PolarHBondContact O-N 3.01Å; Y287-K523 VanDerWaalsContact CZ-O 3.28Å; Y287-K523 PolarHBondContact OH-O 3.42Å; Y287-I525 HydrophobicContact CE1-CB 4.41Å
288P97.4Very high96Very high21 Ų2134.7 Ų34.714%0.13616%0.164CC..G310 helixtrans-53-31.6-179.1-31.638.7000115.2E290 M291 Q292 L337 P526 W529P288-E290 VanDerWaalsContact C-N 3.26Å; P288-E290 PolarHBondContact O-N 2.73Å; P288-M291 PolarHBondContact O-N 3.3Å; P288-M291 VanDerWaalsContact O-N 3.13Å; P288-Q292 WeakPolarHBondContact O-CG 3.36Å; P288-Q292 PolarHBondContact O-N 3.45Å; P288-Q292 PolarHBondContact O-NE2 3.42Å; P288-L337 HydrophobicContact CB-CD1 3.73Å; P288-P526 HydrophobicContact CG-CG 3.83Å; P288-W529 HydrophobicContact CG-CD2 3.7Å; P288-W529 HydrophobicContact CG-CE3 3.83Å; P288-W529 HydrophobicContact CG-CG 4.29Å; P288-W529 HydrophobicContact CG-CH2 4.05Å; P288-W529 HydrophobicContact CG-CZ2 3.91Å; P288-W529 HydrophobicContact CG-CZ3 4Å
289Q96.5Very high96.1Very high115 Ų11536.2 Ų36.254%0.53717%0.17SC..G310 helixtrans-62.4-33.6179.7-63.980.4-1.100112Y287 M291 Q292 T295Y287-Q289 PolarHBondContact O-N 3.14Å; Q289-M291 VanDerWaalsContact C-N 3.27Å; Q289-M291 PolarHBondContact O-N 3.38Å; Q289-Q292 PolarHBondContact O-N 2.95Å; Q289-T295 WeakPolarHBondContact O-CB 3.21Å; Q289-T295 WeakPolarHBondContact O-CG2 3.45Å; Q289-T295 PolarHBondContact O-OG1 3.22Å
290E96.6Very high96.2Very high41 Ų4134.4 Ų34.419%0.19216%0.163CC..G310 helixtrans-71.2-22.9177.5-73.5-79.6109.800112.4V274 I286 Y287 P288 L296 K299V274-E290 PolarHBondContact N-OE2 3.02Å; I286-E290 HydrophobicContact CG2-CB 3.44Å; I286-E290 VanDerWaalsContact CG2-CB 3.44Å; I286-E290 HydrophobicContact CG2-CG 4.23Å; Y287-E290 WeakPolarHBondContact O-CB 3.41Å; Y287-E290 PolarHBondContact O-N 3.01Å; P288-E290 VanDerWaalsContact C-N 3.26Å; P288-E290 PolarHBondContact O-N 2.73Å; E290-L296 WeakPolarHBondContact O-CD2 3.43Å; E290-K299 IonicContact OE1-NZ 2.77Å; E290-K299 PolarHBondContact OE1-NZ 2.91Å; E290-K299 VanDerWaalsContact OE1-NZ 3.14Å; E290-K299 IonicContact OE2-NZ 3.13Å; E290-K299 PolarHBondContact OE2-NZ 3.46Å
291M97.7Very high96.3Very high0 Ų036.1 Ų36.10%018%0.178CC..G310 helixtrans-93.3-3.4178.9-60.1-170.9-17900113.5M273 I286 P288 Q289 V319 Y329 A334 L337 L338 W529M273-M291 HydrophobicContact SD-CG 3.95Å; I286-M291 HydrophobicContact CB-CE 3.84Å; I286-M291 HydrophobicContact CD1-CE 4.27Å; I286-M291 HydrophobicContact CG2-CE 3.78Å; I286-M291 HydrophobicContact CG2-CG 4.02Å; P288-M291 PolarHBondContact O-N 3.3Å; P288-M291 VanDerWaalsContact O-N 3.13Å; Q289-M291 VanDerWaalsContact C-N 3.27Å; Q289-M291 PolarHBondContact O-N 3.38Å; M291-V319 HydrophobicContact CE-CG2 4.12Å; M291-Y329 HydrophobicContact CE-CE1 4.24Å; M291-A334 HydrophobicContact CE-CB 4.3Å; M291-A334 HydrophobicContact SD-CB 4.04Å; M291-L337 HydrophobicContact CB-CB 4.01Å; M291-L337 HydrophobicContact CB-CD1 4.22Å; M291-L338 HydrophobicContact CB-CD2 3.91Å; M291-L338 HydrophobicContact CB-CG 4.31Å; M291-L338 HydrophobicContact CG-CD2 3.99Å; M291-L338 HydrophobicContact CG-CG 4.31Å; M291-L338 HydrophobicContact SD-CD1 4.04Å; M291-L338 HydrophobicContact SD-CD2 4.27Å; M291-L338 HydrophobicContact SD-CG 3.94Å; M291-W529 HydrophobicContact CE-CH2 4.39Å; M291-W529 HydrophobicContact CE-CZ2 4.03Å; M291-W529 HydrophobicContact SD-CH2 3.86Å; M291-W529 HydrophobicContact SD-CZ2 4.01Å
292Q97.4Very high96.4Very high55 Ų5541.9 Ų41.926%0.25721%0.205SC..SBendtrans-70.1140.1-179.6-62.1-60-25.400111.7P288 Q289 E294 T295 L296P288-Q292 WeakPolarHBondContact O-CG 3.36Å; P288-Q292 PolarHBondContact O-N 3.45Å; P288-Q292 PolarHBondContact O-NE2 3.42Å; Q289-Q292 PolarHBondContact O-N 2.95Å; Q292-E294 PolarHBondContact O-N 3.25Å; Q292-T295 PolarHBondContact O-N 3.38Å; Q292-T295 VanDerWaalsContact O-N 3.15Å; Q292-L296 WeakPolarHBondContact O-CG 3.47Å; Q292-L296 PolarHBondContact O-N 2.99Å
293P96.5Very high96.3Very high30 Ų3043 Ų4320%0.19521%0.212CC..Hα-helixtrans-53.2-40.1177.9-2835.9000113.6L296 Q297 K340P293-L296 PolarHBondContact O-N 2.89Å; P293-Q297 WeakPolarHBondContact O-CB 3.39Å; P293-Q297 VanDerWaalsContact O-CG 3.29Å; P293-Q297 WeakPolarHBondContact O-CG 3.5Å; P293-Q297 PolarHBondContact O-N 3.24Å; P293-K340 HydrophobicContact CG-CB 3.63Å; P293-K340 HydrophobicContact CG-CD 4.27Å
294E96.6Very high96.2Very high137 Ų13745.8 Ų45.864%0.6423%0.231SC*.Hα-helixtrans-66.8-42.8-179.1-59.575.2-163.500111.6Q292 Q297 K298Q292-E294 PolarHBondContact O-N 3.25Å; E294-Q297 PolarHBondContact O-N 2.89Å; E294-K298 WeakPolarHBondContact O-CB 3.26Å; E294-K298 PolarHBondContact O-N 3.22Å
295T97.3Very high96.2Very high40 Ų4046.4 Ų46.425%0.24523%0.234CC..Hα-helixtrans-62.9-45.8176-570000110.7Q289 Q292 K298 K299Q289-T295 WeakPolarHBondContact O-CB 3.21Å; Q289-T295 WeakPolarHBondContact O-CG2 3.45Å; Q289-T295 PolarHBondContact O-OG1 3.22Å; Q292-T295 PolarHBondContact O-N 3.38Å; Q292-T295 VanDerWaalsContact O-N 3.15Å; T295-K298 WeakPolarHBondContact O-CB 3.33Å; T295-K298 PolarHBondContact O-N 3.49Å; T295-K299 WeakPolarHBondContact O-CG 3.27Å; T295-K299 PolarHBondContact O-N 3.4Å
296L97.3Very high96.2Very high0 Ų046.4 Ų46.40%023%0.234CC..Hα-helixtrans-65.6-42.6179.6-66.4172.6000111.6V250 M273 E290 Q292 P293 K298 K299 I300 T341V250-L296 HydrophobicContact CG1-CD1 4.31Å; V250-L296 HydrophobicContact CG1-CD2 3.66Å; V250-L296 HydrophobicContact CG2-CD1 4.37Å; V250-L296 HydrophobicContact CG2-CD2 4.29Å; M273-L296 HydrophobicContact CG-CD2 4.05Å; E290-L296 WeakPolarHBondContact O-CD2 3.43Å; Q292-L296 WeakPolarHBondContact O-CG 3.47Å; Q292-L296 PolarHBondContact O-N 2.99Å; P293-L296 PolarHBondContact O-N 2.89Å; L296-K298 PolarHBondContact O-N 3.48Å; L296-K299 PolarHBondContact O-N 3.24Å; L296-I300 VanDerWaalsContact O-CG1 3.24Å; L296-I300 WeakPolarHBondContact O-CG1 3.32Å; L296-I300 PolarHBondContact O-N 3.16Å; L296-T341 HydrophobicContact CD1-CG2 3.8Å
297Q96.1Very high96.1Very high56 Ų5652.7 Ų52.726%0.26226%0.261SS..Hα-helixtrans-64.3-38.2175-74.5-62.2-36.100112.8P293 E294 I300 S301 G311 Q312P293-Q297 WeakPolarHBondContact O-CB 3.39Å; P293-Q297 VanDerWaalsContact O-CG 3.29Å; P293-Q297 WeakPolarHBondContact O-CG 3.5Å; P293-Q297 PolarHBondContact O-N 3.24Å; E294-Q297 PolarHBondContact O-N 2.89Å; Q297-I300 PolarHBondContact O-N 3.39Å; Q297-S301 PolarHBondContact O-N 3.5Å; Q297-G311 VanDerWaalsContact OE1-CA 3.3Å; Q297-Q312 PolarHBondContact NE2-O 3.39Å; Q297-Q312 VanDerWaalsContact NE2-O 3.12Å
298K96.6Very high95.9Very high122 Ų12255.6 Ų55.653%0.5328%0.28SS..Hα-helixtrans-58.8-50.6172.6-178.5-177.8172.6-172.20110.7E294 T295 L296 I300 S301 E302E294-K298 WeakPolarHBondContact O-CB 3.26Å; E294-K298 PolarHBondContact O-N 3.22Å; T295-K298 WeakPolarHBondContact O-CB 3.33Å; T295-K298 PolarHBondContact O-N 3.49Å; L296-K298 PolarHBondContact O-N 3.48Å; K298-I300 VanDerWaalsContact C-N 3.31Å; K298-I300 PolarHBondContact O-N 2.97Å; K298-S301 PolarHBondContact O-N 3.24Å; K298-S301 PolarHBondContact O-OG 3.48Å; K298-E302 VanDerWaalsContact CE-CD 3.48Å; K298-E302 WeakPolarHBondContact CE-OE1 3.31Å; K298-E302 WeakPolarHBondContact CE-OE2 3.25Å; K298-E302 HydrophobicContact CG-CG 4.44Å; K298-E302 IonicContact NZ-OE1 2.78Å; K298-E302 WeakPolarHBondContact O-CG 3.47Å; K298-E302 PolarHBondContact O-N 3.41Å
299K96.2Very high95.7Very high35 Ų3555.7 Ų55.715%0.15228%0.278CS..Hα-helixtrans-60.8-38.4177.9-68.6177.8172.6-173.40112.8V271 Y272 E290 T295 L296 S301 E302 S303V271-K299 HydrophobicContact CG1-CB 3.33Å; V271-K299 HydrophobicContact CG1-CD 4.25Å; V271-K299 HydrophobicContact CG1-CG 4.43Å; Y272-K299 PolarHBondContact O-NZ 3.36Å; E290-K299 IonicContact OE1-NZ 2.77Å; E290-K299 PolarHBondContact OE1-NZ 2.91Å; E290-K299 VanDerWaalsContact OE1-NZ 3.14Å; E290-K299 IonicContact OE2-NZ 3.13Å; E290-K299 PolarHBondContact OE2-NZ 3.46Å; T295-K299 WeakPolarHBondContact O-CG 3.27Å; T295-K299 PolarHBondContact O-N 3.4Å; L296-K299 PolarHBondContact O-N 3.24Å; K299-S301 VanDerWaalsContact C-N 3.3Å; K299-S301 PolarHBondContact O-N 3.03Å; K299-E302 PolarHBondContact O-N 3.18Å; K299-S303 WeakPolarHBondContact O-CB 3.43Å; K299-S303 PolarHBondContact O-N 3.09Å
300I96.4Very high95.4Very high0 Ų053 Ų530%028%0.276CS..Hα-helixtrans-58.2-44.7173.5-69.4163.6000110.5V248 V271 L296 Q297 K298 T306 K307 P314V248-I300 HydrophobicContact CG1-CD1 3.94Å; V248-I300 HydrophobicContact CG1-CG1 3.87Å; V248-I300 HydrophobicContact CG1-CG2 4.49Å; V271-I300 HydrophobicContact CB-CG1 4.42Å; V271-I300 HydrophobicContact CG1-CG1 4.43Å; V271-I300 HydrophobicContact CG2-CG1 3.73Å; L296-I300 VanDerWaalsContact O-CG1 3.24Å; L296-I300 WeakPolarHBondContact O-CG1 3.32Å; L296-I300 PolarHBondContact O-N 3.16Å; Q297-I300 PolarHBondContact O-N 3.39Å; K298-I300 VanDerWaalsContact C-N 3.31Å; K298-I300 PolarHBondContact O-N 2.97Å; I300-T306 WeakPolarHBondContact CA-OG1 3.44Å; I300-T306 CarbonylContact O-C 3.57Å; I300-T306 PolarHBondContact O-OG1 3.07Å; I300-K307 WeakPolarHBondContact O-CA 3.28Å; I300-K307 PolarHBondContact O-N 2.78Å; I300-P314 HydrophobicContact CD1-CG 3.86Å
301S96.2Very high95.1Very high56 Ų5654 Ų5439%0.39230%0.298SS..Hα-helixtrans-72-26.4-178.473.10000114.4Q297 K298 K299 K307Q297-S301 PolarHBondContact O-N 3.5Å; K298-S301 PolarHBondContact O-N 3.24Å; K298-S301 PolarHBondContact O-OG 3.48Å; K299-S301 VanDerWaalsContact C-N 3.3Å; K299-S301 PolarHBondContact O-N 3.03Å; S301-K307 VanDerWaalsContact O-CB 3.28Å; S301-K307 WeakPolarHBondContact O-CB 3.47Å
302E94.6Very high94.8Very high123 Ų12357.8 Ų57.858%0.57532%0.316SS*.Hα-helixtrans-91.1-26.8-177.2-70.8175.8163.300112.9K298 K299K298-E302 VanDerWaalsContact CE-CD 3.48Å; K298-E302 WeakPolarHBondContact CE-OE1 3.31Å; K298-E302 WeakPolarHBondContact CE-OE2 3.25Å; K298-E302 HydrophobicContact CG-CG 4.44Å; K298-E302 IonicContact NZ-OE1 2.78Å; K298-E302 WeakPolarHBondContact O-CG 3.47Å; K298-E302 PolarHBondContact O-N 3.41Å; K299-E302 PolarHBondContact O-N 3.18Å
303S93Very high94.6Very high22 Ų2260 Ų6015%0.15432%0.324CS..SBendtrans-69.1131.1-178167.30000112.2K299 L305 T306 K307K299-S303 WeakPolarHBondContact O-CB 3.43Å; K299-S303 PolarHBondContact O-N 3.09Å; S303-L305 PolarHBondContact O-N 3.02Å; S303-L305 VanDerWaalsContact O-N 3.16Å; S303-L305 PolarHBondContact OG-N 3.32Å; S303-T306 WeakPolarHBondContact CB-OG1 3.38Å; S303-T306 PolarHBondContact O-N 2.92Å; S303-T306 VanDerWaalsContact O-N 3.16Å; S303-K307 VanDerWaalsContact O-CB 3.31Å; S303-K307 WeakPolarHBondContact O-CB 3.17Å; S303-K307 PolarHBondContact O-N 3.42Å
304P93.5Very high94.7Very high60 Ų6058.7 Ų58.739%0.3932%0.316SS..THydrogen-bonded Turntrans-54.2-34.1174.2-26.234.5000113.5V661P304-V661 HydrophobicContact CG-CG1 4.06Å
305L94.9Very high94.7Very high12 Ų1253.4 Ų53.46%0.06329%0.294CS..THydrogen-bonded Turntrans-72.3-37.3-179-61-174000112.4K269 P270 S303 A662 T665K269-L305 HydrophobicContact CD-CB 4.38Å; K269-L305 WeakPolarHBondContact CD-O 3.36Å; K269-L305 WeakPolarHBondContact CE-O 3.46Å; K269-L305 PolarHBondContact NZ-O 3.5Å; P270-L305 HydrophobicContact CG-CD1 4.49Å; S303-L305 PolarHBondContact O-N 3.02Å; S303-L305 VanDerWaalsContact O-N 3.16Å; S303-L305 PolarHBondContact OG-N 3.32Å; L305-A662 HydrophobicContact CD1-CB 3.64Å; L305-A662 HydrophobicContact CG-CB 4Å; L305-T665 HydrophobicContact CD1-CG2 4.36Å; L305-T665 HydrophobicContact CD2-CG2 4.15Å
306T95.5Very high94.7Very high0 Ų051.5 Ų51.50%028%0.282CS..THydrogen-bonded Turntrans-118.7-2.6-166.559.60000115.4V248 K269 V271 I300 S303 D308 K309V248-T306 HydrophobicContact CG1-CG2 4.27Å; V248-T306 HydrophobicContact CG2-CG2 4.15Å; K269-T306 HydrophobicContact CB-CG2 3.56Å; K269-T306 HydrophobicContact CD-CG2 4.45Å; V271-T306 HydrophobicContact CG2-CG2 3.85Å; I300-T306 WeakPolarHBondContact CA-OG1 3.44Å; I300-T306 CarbonylContact O-C 3.57Å; I300-T306 PolarHBondContact O-OG1 3.07Å; S303-T306 WeakPolarHBondContact CB-OG1 3.38Å; S303-T306 PolarHBondContact O-N 2.92Å; S303-T306 VanDerWaalsContact O-N 3.16Å; T306-D308 PolarHBondContact O-N 3.43Å; T306-D308 VanDerWaalsContact O-N 3.1Å; T306-K309 WeakPolarHBondContact O-CA 3.42Å; T306-K309 WeakPolarHBondContact O-CB 3.43Å; T306-K309 PolarHBondContact O-N 2.98Å
307K94.3Very high94.8Very high132 Ų13251.6 Ų51.657%0.57428%0.283SS*.G310 helixtrans-55.3-29.9-177.962.9-175.4177.5-172.70114.2I300 S301 S303 K309I300-K307 WeakPolarHBondContact O-CA 3.28Å; I300-K307 PolarHBondContact O-N 2.78Å; S301-K307 VanDerWaalsContact O-CB 3.28Å; S301-K307 WeakPolarHBondContact O-CB 3.47Å; S303-K307 VanDerWaalsContact O-CB 3.31Å; S303-K307 WeakPolarHBondContact O-CB 3.17Å; S303-K307 PolarHBondContact O-N 3.42Å; K307-K309 PolarHBondContact O-N 2.91Å
308D94.3Very high94.9Very high111 Ų11149 Ų4959%0.59427%0.271SS*.G310 helixtrans-71.1-7175.363.4-46.8000113.5K269 T306K269-D308 IonicContact NZ-OD1 3.68Å; K269-D308 IonicContact NZ-OD2 3.82Å; T306-D308 PolarHBondContact O-N 3.43Å; T306-D308 VanDerWaalsContact O-N 3.1Å
309K93Very high95Very high22 Ų2243.2 Ų43.210%0.09625%0.246CC..G310 helixtrans-120.918-175.5-57.1-179.6-173.2171.80112.8N246 V248 T306 K307 G311 Q312N246-K309 VanDerWaalsContact C-NZ 3.34Å; N246-K309 VanDerWaalsContact CA-NZ 3.28Å; N246-K309 PolarHBondContact O-NZ 3.08Å; N246-K309 PolarHBondContact OD1-NZ 2.99Å; V248-K309 HydrophobicContact CG2-CB 3.62Å; V248-K309 HydrophobicContact CG2-CD 3.54Å; V248-K309 HydrophobicContact CG2-CG 4.19Å; T306-K309 WeakPolarHBondContact O-CA 3.42Å; T306-K309 WeakPolarHBondContact O-CB 3.43Å; T306-K309 PolarHBondContact O-N 2.98Å; K307-K309 PolarHBondContact O-N 2.91Å; K309-G311 PolarHBondContact O-N 3.38Å; K309-Q312 HydrophobicContact CB-CB 4.37Å; K309-Q312 WeakPolarHBondContact O-CB 3.42Å; K309-Q312 PolarHBondContact O-N 3.25Å
310A90.4Very high95.1Very high58 Ų5842.2 Ų42.248%0.47924%0.243SC..THydrogen-bonded Turntrans-54.1133.217500000111.2Q312A310-Q312 VanDerWaalsContact C-N 3.31Å
311G89.3Confident95.2Very high64 Ų6442.2 Ų42.266%0.6624%0.243SC*.THydrogen-bonded Turntrans85.6-9.6-175.500000114.9Q297 K309Q297-G311 VanDerWaalsContact OE1-CA 3.3Å; K309-G311 PolarHBondContact O-N 3.38Å
312Q90.8Very high95.2Very high79 Ų7939.6 Ų39.637%0.36922%0.224SC..PPolyproline II helixtrans-71.1136.3171.8-171.3173.3-14.400110.1Q297 K309 A310 P314Q297-Q312 PolarHBondContact NE2-O 3.39Å; Q297-Q312 VanDerWaalsContact NE2-O 3.12Å; K309-Q312 HydrophobicContact CB-CB 4.37Å; K309-Q312 WeakPolarHBondContact O-CB 3.42Å; K309-Q312 PolarHBondContact O-N 3.25Å; A310-Q312 VanDerWaalsContact C-N 3.31Å; Q312-P314 WeakPolarHBondContact O-CD 3.49Å
313K94.1Very high95.3Very high101 Ų10133.8 Ų33.844%0.43920%0.197SC..PPolyproline II helixtrans-70.9123.6172.5-172.2179.8179.7177.40109.3T341 D343K313-T341 VanDerWaalsContact CE-O 3.22Å; K313-T341 WeakPolarHBondContact CE-O 3.31Å; K313-T341 WeakPolarHBondContact CG-O 3.02Å; K313-D343 IonicContact NZ-OD1 3.14Å; K313-D343 PolarHBondContact NZ-OD1 3.14Å; K313-D343 IonicContact NZ-OD2 3.42Å; K313-D343 PolarHBondContact NZ-OD2 2.96Å
314P97.4Very high95.4Very high3 Ų333.5 Ų33.52%0.01919%0.193CC..PPolyproline II helixtrans-58.8136.9175.5-28.138000113V248 V250 I300 Q312 Y316 T341 S342V248-P314 HydrophobicContact CG1-CG 4.39Å; V248-P314 CarbonylContact O-C 3.6Å; V248-P314 VanDerWaalsContact O-CA 3.24Å; V248-P314 WeakPolarHBondContact O-CA 3.45Å; V250-P314 HydrophobicContact CG2-CB 3.83Å; V250-P314 HydrophobicContact CG2-CG 3.83Å; I300-P314 HydrophobicContact CD1-CG 3.86Å; Q312-P314 WeakPolarHBondContact O-CD 3.49Å; P314-Y316 VanDerWaalsContact C-N 3.31Å; P314-Y316 PolarHBondContact O-N 3.39Å; P314-T341 HydrophobicContact CB-CG2 4.21Å; P314-T341 HydrophobicContact CG-CG2 3.62Å; P314-S342 WeakPolarHBondContact O-CB 3.47Å; P314-S342 PolarHBondContact O-OG 3.33Å
315S97.1Very high95.5Very high26 Ų2630.7 Ų30.718%0.18217%0.174CC..SBendtrans-79.2-15.8-174.966.30000113.8D247 V248 S342D247-S315 WeakPolarHBondContact CB-OG 3.31Å; D247-S315 PolarHBondContact OD2-OG 3.11Å; V248-S315 PolarHBondContact O-N 3.48Å; S315-S342 VanDerWaalsContact C-OG 3.32Å; S315-S342 PolarHBondContact O-OG 2.82Å
316Y98.2Very high95.6Very high0 Ų030.1 Ų30.10%017%0.171CC..  trans-161.5144.7-174.7168.1-93.3000111.2I238 M239 C242 M243 V249 V250 P314 V318 S342 R344 H346I238-Y316 HydrophobicContact CG2-CE2 3.89Å; M239-Y316 HydrophobicContact CG-CE1 4.29Å; C242-Y316 HydrophobicContact CB-CD2 3.92Å; C242-Y316 HydrophobicContact CB-CG 4.47Å; M243-Y316 HydrophobicContact CE-CD1 3.28Å; M243-Y316 HydrophobicContact CE-CD2 4Å; M243-Y316 HydrophobicContact CE-CE1 3.67Å; M243-Y316 HydrophobicContact CE-CE2 4.36Å; M243-Y316 HydrophobicContact CE-CG 3.42Å; M243-Y316 VanDerWaalsContact CE-CG 3.42Å; V249-Y316 HydrophobicContact CB-CD1 4.3Å; V249-Y316 HydrophobicContact CG1-CD1 4.41Å; V250-Y316 PolarHBondContact N-O 3.24Å; P314-Y316 VanDerWaalsContact C-N 3.31Å; P314-Y316 PolarHBondContact O-N 3.39Å; Y316-V318 HydrophobicContact CE1-CB 3.58Å; Y316-V318 HydrophobicContact CE1-CG1 3.67Å; Y316-V318 WeakPolarHBondContact OH-CB 3.14Å; Y316-S342 PolarHBondContact N-OG 2.97Å; Y316-R344 WeakPolarHBondContact CA-O 3.49Å; Y316-H346 HydrophobicContact CE2-CB 3.47Å; Y316-H346 VanDerWaalsContact CE2-CB 3.47Å; Y316-H346 AromaticContact CE2-ND1 3.91Å; Y316-H346 AromaticContact CZ-ND1 3.64Å; Y316-H346 PolarHBondContact OH-ND1 3.05Å
317C98.6Very high95.7Very high2 Ų230.1 Ų30.11%0.01417%0.171CC..EExtended strand (participates in β ladder)trans-127.8135.9171.1-620000110.2V250 S342 R344 L345 H346V250-C317 HydrophobicContact CB-CB 4.27Å; V250-C317 CarbonylContact O-C 3.56Å; V250-C317 VanDerWaalsContact O-CA 3.28Å; V250-C317 WeakPolarHBondContact O-CA 3.46Å; C317-S342 WeakPolarHBondContact SG-CB 3.4Å; C317-R344 PolarHBondContact N-O 3.02Å; C317-L345 HydrophobicContact CB-CD2 3.82Å; C317-L345 CarbonylContact O-C 3.54Å; C317-L345 WeakPolarHBondContact O-CA 3.24Å; C317-H346 PolarHBondContact O-N 3.19Å
318V98.6Very high95.9Very high0 Ų023.8 Ų23.80%014%0.144CC..EExtended strand (participates in β ladder)trans-126.6137173.860.90000113V250 V251 D252 I259 M273 Y316 H346V250-V318 PolarHBondContact O-N 2.89Å; V251-V318 HydrophobicContact CB-CG1 4.15Å; V251-V318 HydrophobicContact CG1-CG1 3.94Å; V251-V318 HydrophobicContact CG2-CG1 4.05Å; D252-V318 WeakPolarHBondContact CB-O 3.42Å; D252-V318 PolarHBondContact N-O 3.26Å; I259-V318 HydrophobicContact CD1-CG2 4.09Å; I259-V318 HydrophobicContact CG2-CG1 4.15Å; M273-V318 WeakPolarHBondContact CE-O 3.31Å; Y316-V318 HydrophobicContact CE1-CB 3.58Å; Y316-V318 HydrophobicContact CE1-CG1 3.67Å; Y316-V318 WeakPolarHBondContact OH-CB 3.14Å; V318-H346 CarbonylContact C-O 3.57Å; V318-H346 VanDerWaalsContact CA-O 3.23Å; V318-H346 WeakPolarHBondContact CA-O 3.41Å; V318-H346 HydrophobicContact CB-CB 4.26Å; V318-H346 HydrophobicContact CG2-CB 4.15Å; V318-H346 WeakPolarHBondContact CG2-O 3.26Å
319V98.4Very high96Very high1 Ų118.5 Ų18.51%0.00612%0.116CC..EExtended strand (participates in β ladder)trans-130.6137.1175.2178.70000109.5M273 I286 M291 Y329 L338 H346 F347 D348M273-V319 HydrophobicContact CE-CG2 3.66Å; I286-V319 HydrophobicContact CD1-CG1 4.37Å; M291-V319 HydrophobicContact CE-CG2 4.12Å; V319-Y329 HydrophobicContact CG1-CD2 4.2Å; V319-Y329 HydrophobicContact CG1-CE2 3.86Å; V319-L338 HydrophobicContact CG2-CD1 3.63Å; V319-H346 PolarHBondContact N-O 2.79Å; V319-F347 HydrophobicContact CB-CD1 4.45Å; V319-F347 CarbonylContact O-C 3.47Å; V319-F347 WeakPolarHBondContact O-CA 3.49Å; V319-D348 PolarHBondContact O-N 3.23Å
320T98.1Very high96.2Very high15 Ų1517.6 Ų17.69%0.09211%0.112CC..EExtended strand (participates in β ladder)trans-83.2116.2173.6-62.30000109.8D252 Y329D252-T320 PolarHBondContact OD2-N 3.38Å; D252-T320 VanDerWaalsContact OD2-N 3.07Å; T320-Y329 VanDerWaalsContact O-CE2 3.23Å; T320-Y329 WeakPolarHBondContact O-CE2 3.33Å
321N98Very high96.6Very high0 Ų014.8 Ų14.80%09%0.089CC..SBendtrans-133.8118.1-176.7-178.145.7000112.9Y329 F347 D348 E349 Y352 H364N321-Y329 HydrophobicContact CB-CD2 4.16Å; N321-Y329 PolarHBondContact OD1-N 3.18Å; N321-F347 HydrophobicContact CB-CD1 3.99Å; N321-D348 PolarHBondContact N-O 3.25Å; N321-E349 HydrophobicContact CB-CG 4.39Å; N321-E349 PolarHBondContact ND2-OE1 3.16Å; N321-E349 VanDerWaalsContact ND2-OE1 3.13Å; N321-E349 WeakPolarHBondContact O-CA 3.45Å; N321-E349 WeakPolarHBondContact O-CB 3.16Å; N321-E349 VanDerWaalsContact O-CG 3.25Å; N321-E349 WeakPolarHBondContact O-CG 3.3Å; N321-Y352 WeakPolarHBondContact O-CB 3.4Å; N321-H364 PolarHBondContact ND2-O 2.94Å
322C97.4Very high96.9Very high1 Ų116.1 Ų16.11%0.0078%0.076CC..SBendcis-70.9170.1-9.252.50000112.5V327 C328 Y352 K536C322-V327 WeakPolarHBondContact CA-O 3.26Å; C322-V327 VanDerWaalsContact CB-O 3.3Å; C322-V327 WeakPolarHBondContact CB-O 3.3Å; C322-C328 HydrophobicContact CB-CB 4.21Å; C322-C328 VanDerWaalsContact CB-SG 3.57Å; C322-Y352 HydrophobicContact CB-CD2 4.41Å; C322-Y352 HydrophobicContact CB-CG 4.48Å; C322-K536 PolarHBondContact SG-NZ 2.97Å; C322-K536 VanDerWaalsContact SG-NZ 3.4Å
323T96.6Very high97.3Very high0 Ų015.9 Ų15.90%08%0.075CC..  trans-62164.8165.573.30000110.3I283 D325 G326 V327 Y329I283-T323 HydrophobicContact CG2-CG2 4.06Å; I283-T323 PolarHBondContact O-OG1 3.21Å; T323-D325 PolarHBondContact O-N 3.49Å; T323-G326 PolarHBondContact O-N 3.29Å; T323-V327 HydrophobicContact CG2-CB 4.04Å; T323-V327 PolarHBondContact N-O 2.85Å; T323-V327 WeakPolarHBondContact OG1-CB 2.84Å; T323-V327 PolarHBondContact OG1-N 2.86Å; T323-V327 VanDerWaalsContact OG1-N 3.11Å; T323-Y329 HydrophobicContact CG2-CE2 4.34Å
324Y94.9Very high97.4Very high17 Ų1711 Ų117%0.0675%0.054CC..THydrogen-bonded Turntrans-54.5-40.7178.2-168.6-83.2000112.1G326 W351 T572 R573 M580 P700Y324-G326 PolarHBondContact O-N 3.06Å; Y324-W351 HydrophobicContact CD2-CZ2 4.19Å; Y324-W351 AromaticContact CD2-NE1 3.52Å; Y324-W351 AromaticContact CE2-CE2 3.89Å; Y324-W351 AromaticContact CE2-CZ2 3.59Å; Y324-W351 HydrophobicContact CE2-CZ2 3.59Å; Y324-W351 AromaticContact CE2-NE1 3.84Å; Y324-T572 HydrophobicContact CE1-CG2 3.86Å; Y324-T572 PolarHBondContact OH-O 3.48Å; Y324-T572 PolarHBondContact OH-OG1 3.03Å; Y324-R573 HydrophobicContact CD1-CB 4.35Å; Y324-R573 HydrophobicContact CE1-CB 3.64Å; Y324-R573 HydrophobicContact CE1-CG 4.39Å; Y324-M580 HydrophobicContact CD1-SD 3.86Å; Y324-M580 HydrophobicContact CE1-SD 3.84Å; Y324-M580 WeakPolarHBondContact O-CE 3.48Å; Y324-P700 HydrophobicContact CD1-CB 4Å; Y324-P700 HydrophobicContact CD2-CB 3.26Å; Y324-P700 HydrophobicContact CD2-CG 4.41Å; Y324-P700 HydrophobicContact CE1-CB 4.27Å; Y324-P700 HydrophobicContact CE2-CB 3.53Å; Y324-P700 HydrophobicContact CG-CB 3.5Å; Y324-P700 HydrophobicContact CG-CG 4.34Å
325D95.1Very high97.5Very high0 Ų011.6 Ų11.60%06%0.056CC..THydrogen-bonded Turntrans-79.35.3-178.2-59.2-57.8000114.1I282 I283 T323 R573I282-D325 HydrophobicContact CG2-CB 3.64Å; I283-D325 PolarHBondContact N-OD2 3.41Å; T323-D325 PolarHBondContact O-N 3.49Å; D325-R573 IonicContact OD1-CZ 3.55Å; D325-R573 IonicContact OD1-NH1 3.72Å; D325-R573 PolarHBondContact OD1-NH1 3.3Å; D325-R573 IonicContact OD2-CZ 2.74Å; D325-R573 IonicContact OD2-NH1 3.52Å; D325-R573 PolarHBondContact OD2-NH1 3.31Å
326G96.9Very high97.5Very high0 Ų013.6 Ų13.60%07%0.065CC..  trans84.724.7176.800000114.9T323 Y324 C328 D533T323-G326 PolarHBondContact O-N 3.29Å; Y324-G326 PolarHBondContact O-N 3.06Å; G326-C328 PolarHBondContact O-N 2.97Å; G326-D533 WeakPolarHBondContact O-CB 3.47Å; G326-D533 PolarHBondContact O-N 3.4Å
327V97.8Very high97.4Very high0 Ų014.7 Ų14.70%07%0.071CC..EExtended strand (participates in β ladder)trans-84108.5169.1-174.20000108.5I283 P285 C322 T323 W480 M513 F522I283-V327 WeakPolarHBondContact O-CG2 3.46Å; P285-V327 HydrophobicContact CB-CG1 4.41Å; P285-V327 HydrophobicContact CG-CG1 4.49Å; C322-V327 WeakPolarHBondContact CA-O 3.26Å; C322-V327 VanDerWaalsContact CB-O 3.3Å; C322-V327 WeakPolarHBondContact CB-O 3.3Å; T323-V327 HydrophobicContact CG2-CB 4.04Å; T323-V327 PolarHBondContact N-O 2.85Å; T323-V327 WeakPolarHBondContact OG1-CB 2.84Å; T323-V327 PolarHBondContact OG1-N 2.86Å; T323-V327 VanDerWaalsContact OG1-N 3.11Å; V327-W480 HydrophobicContact CG2-CH2 4.29Å; V327-M513 HydrophobicContact CG1-CE 4.11Å; V327-M513 HydrophobicContact CG2-CE 3.98Å; V327-F522 HydrophobicContact CG2-CE2 4.38Å
328C98.2Very high97.4Very high0 Ų014.7 Ų14.70%07%0.071CC..EExtended strand (participates in β ladder)trans-91.5129.5179-50.70000109.4C322 G326 Y352 H364 S530 M531C322-C328 HydrophobicContact CB-CB 4.21Å; C322-C328 VanDerWaalsContact CB-SG 3.57Å; G326-C328 PolarHBondContact O-N 2.97Å; C328-Y352 HydrophobicContact CB-CE1 4.46Å; C328-Y352 WeakPolarHBondContact SG-CE2 3.38Å; C328-Y352 PolarHBondContact SG-OH 3.38Å; C328-H364 HydrophobicContact CB-CB 4.29Å; C328-S530 CarbonylContact O-C 3.57Å; C328-S530 WeakPolarHBondContact O-CA 3.38Å; C328-S530 WeakPolarHBondContact O-CB 3.36Å; C328-M531 HydrophobicContact CB-CG 3.74Å; C328-M531 PolarHBondContact N-O 3.36Å; C328-M531 PolarHBondContact O-N 2.9Å
329Y96.8Very high97.4Very high0 Ų017.1 Ų17.10%08%0.082CC..EExtended strand (participates in β ladder)trans-73.6151.3172.9-66.8-93.5000110.1P285 I286 M291 V319 T320 N321 T323 A331 H364 W529P285-Y329 WeakPolarHBondContact CA-OH 3.13Å; P285-Y329 HydrophobicContact CB-CD1 4.02Å; P285-Y329 HydrophobicContact CB-CE1 3.48Å; P285-Y329 VanDerWaalsContact CB-CE1 3.48Å; I286-Y329 HydrophobicContact CB-CE1 4.09Å; I286-Y329 WeakPolarHBondContact CG1-OH 3.27Å; I286-Y329 PolarHBondContact N-OH 2.85Å; M291-Y329 HydrophobicContact CE-CE1 4.24Å; V319-Y329 HydrophobicContact CG1-CD2 4.2Å; V319-Y329 HydrophobicContact CG1-CE2 3.86Å; T320-Y329 VanDerWaalsContact O-CE2 3.23Å; T320-Y329 WeakPolarHBondContact O-CE2 3.33Å; N321-Y329 HydrophobicContact CB-CD2 4.16Å; N321-Y329 PolarHBondContact OD1-N 3.18Å; T323-Y329 HydrophobicContact CG2-CE2 4.34Å; Y329-A331 PolarHBondContact O-N 3Å; Y329-H364 CarbonylContact O-C 3.55Å; Y329-H364 WeakPolarHBondContact O-CA 3.12Å; Y329-H364 VanDerWaalsContact O-CB 3.3Å; Y329-H364 WeakPolarHBondContact O-CB 3.37Å; Y329-H364 PolarHBondContact O-CD2 3.21Å; Y329-H364 VanDerWaalsContact O-O 3.14Å; Y329-W529 HydrophobicContact CD1-CZ2 4.21Å
330N98.1Very high97.3Very high2 Ų222.8 Ų22.81%0.01111%0.107CC..  trans-66.989.1153.3-176.3-32.1000108.1K332 E333 A334 H364 N528 W529N330-K332 PolarHBondContact O-N 2.86Å; N330-K332 PolarHBondContact OD1-N 2.85Å; N330-E333 HydrophobicContact CB-CB 4.35Å; N330-E333 VanDerWaalsContact ND2-CD 3.31Å; N330-E333 PolarHBondContact ND2-OE1 3.49Å; N330-E333 PolarHBondContact O-N 3.11Å; N330-E333 PolarHBondContact OD1-N 3.25Å; N330-A334 PolarHBondContact O-N 2.91Å; N330-H364 PolarHBondContact N-CD2 2.91Å; N330-N528 WeakPolarHBondContact CB-O 3.43Å; N330-N528 PolarHBondContact ND2-ND2 3.22Å; N330-N528 VanDerWaalsContact ND2-ND2 3.14Å; N330-N528 PolarHBondContact ND2-O 3.2Å; N330-W529 PolarHBondContact N-O 3.19Å
331A97.7Very high97.3Very high0 Ų022.4 Ų22.40%010%0.104CC..Hα-helixtrans-64.6-23.8-172.500000112.4Y329 Q335 F347 D363 Y365 R368Y329-A331 PolarHBondContact O-N 3Å; A331-Q335 VanDerWaalsContact O-CB 3.23Å; A331-Q335 WeakPolarHBondContact O-CB 3.35Å; A331-Q335 PolarHBondContact O-N 3.16Å; A331-F347 HydrophobicContact CB-CE1 4.1Å; A331-F347 HydrophobicContact CB-CZ 4.42Å; A331-D363 PolarHBondContact N-O 3.43Å; A331-Y365 WeakPolarHBondContact CB-O 3.48Å; A331-R368 PolarHBondContact O-NH1 3.1Å
332K97.1Very high97.2Very high92 Ų9222.5 Ų22.540%0.411%0.105SC..Hα-helixtrans-66.3-52.8171.4-179.4-177.8174.4-174.30111.2N330 A334 Q335 D336 D363N330-K332 PolarHBondContact O-N 2.86Å; N330-K332 PolarHBondContact OD1-N 2.85Å; K332-A334 PolarHBondContact O-N 2.95Å; K332-Q335 WeakPolarHBondContact O-CB 3.33Å; K332-Q335 PolarHBondContact O-N 2.86Å; K332-D336 PolarHBondContact O-N 3.13Å; K332-D363 HydrophobicContact CB-CB 4.29Å; K332-D363 PolarHBondContact N-O 3.27Å
333E97.4Very high97.2Very high73 Ų7324.7 Ų24.734%0.34112%0.116SC..Hα-helixtrans-65.7-39.4178.7-68.9-179.3-159.400112.2N330 Q335 D336 L337 W529N330-E333 HydrophobicContact CB-CB 4.35Å; N330-E333 VanDerWaalsContact ND2-CD 3.31Å; N330-E333 PolarHBondContact ND2-OE1 3.49Å; N330-E333 PolarHBondContact O-N 3.11Å; N330-E333 PolarHBondContact OD1-N 3.25Å; E333-Q335 VanDerWaalsContact C-N 3.32Å; E333-Q335 PolarHBondContact O-N 3.01Å; E333-D336 PolarHBondContact O-N 3.06Å; E333-L337 WeakPolarHBondContact O-CG 3.49Å; E333-L337 PolarHBondContact O-N 3.08Å; E333-W529 HydrophobicContact CB-CE3 4.17Å; E333-W529 HydrophobicContact CB-CZ3 3.74Å
334A97.8Very high97.3Very high0 Ų026.6 Ų26.60%012%0.124CC..Hα-helixtrans-60.7-40.8173.700000112M291 N330 K332 L337 L338 F347 W529M291-A334 HydrophobicContact CE-CB 4.3Å; M291-A334 HydrophobicContact SD-CB 4.04Å; N330-A334 PolarHBondContact O-N 2.91Å; K332-A334 PolarHBondContact O-N 2.95Å; A334-L337 PolarHBondContact O-N 2.78Å; A334-L338 WeakPolarHBondContact O-CB 3.4Å; A334-L338 WeakPolarHBondContact O-CG 3.37Å; A334-L338 PolarHBondContact O-N 3.1Å; A334-F347 HydrophobicContact CB-CE1 4.32Å; A334-W529 HydrophobicContact CB-CH2 3.95Å; A334-W529 HydrophobicContact CB-CZ3 4.5Å
335Q97.9Very high97.5Very high14 Ų1425.8 Ų25.87%0.06512%0.121CC..Hα-helixtrans-61.9-47172.4168177.6-39.900111.6A331 K332 E333 L337 L338 E339 L345 F347 P377A331-Q335 VanDerWaalsContact O-CB 3.23Å; A331-Q335 WeakPolarHBondContact O-CB 3.35Å; A331-Q335 PolarHBondContact O-N 3.16Å; K332-Q335 WeakPolarHBondContact O-CB 3.33Å; K332-Q335 PolarHBondContact O-N 2.86Å; E333-Q335 VanDerWaalsContact C-N 3.32Å; E333-Q335 PolarHBondContact O-N 3.01Å; Q335-L337 PolarHBondContact O-N 3.07Å; Q335-L338 PolarHBondContact O-N 3.39Å; Q335-E339 WeakPolarHBondContact O-CB 3.27Å; Q335-E339 WeakPolarHBondContact O-CG 3.45Å; Q335-E339 PolarHBondContact O-N 3.13Å; Q335-L345 HydrophobicContact CB-CD1 4.2Å; Q335-L345 HydrophobicContact CG-CD1 3.85Å; Q335-F347 HydrophobicContact CB-CE2 4.48Å; Q335-F347 HydrophobicContact CB-CZ 4.23Å; Q335-P377 HydrophobicContact CG-CG 4.32Å
336D97.4Very high97.7Very high69 Ų6925.9 Ų25.937%0.36912%0.121SC..Hα-helixtrans-61.4-30.6-178.9-69.3-11.2000112.4K332 E333 K340K332-D336 PolarHBondContact O-N 3.13Å; E333-D336 PolarHBondContact O-N 3.06Å; D336-K340 VanDerWaalsContact O-CE 3.26Å; D336-K340 WeakPolarHBondContact O-CE 3.36Å
337L97.6Very high97.8Very high23 Ų2326 Ų2612%0.1212%0.122CC..Hα-helixtrans-75.7-51.2172.6-67.3177.5000111.9P288 M291 E333 A334 Q335 E339 K340 W529P288-L337 HydrophobicContact CB-CD1 3.73Å; M291-L337 HydrophobicContact CB-CB 4.01Å; M291-L337 HydrophobicContact CB-CD1 4.22Å; E333-L337 WeakPolarHBondContact O-CG 3.49Å; E333-L337 PolarHBondContact O-N 3.08Å; A334-L337 PolarHBondContact O-N 2.78Å; Q335-L337 PolarHBondContact O-N 3.07Å; L337-E339 PolarHBondContact O-N 3.27Å; L337-K340 WeakPolarHBondContact O-CB 3.39Å; L337-K340 PolarHBondContact O-N 2.52Å; L337-W529 HydrophobicContact CD1-CH2 3.8Å; L337-W529 HydrophobicContact CD1-CZ3 4.03Å
338L97.9Very high97.8Very high2 Ų226.4 Ų26.41%0.0112%0.124CC..Hα-helixtrans-72.7-26.9-173.4-69172.5000113.5M273 M291 V319 A334 Q335 K340 T341 S342 L345M273-L338 HydrophobicContact SD-CD2 3.97Å; M291-L338 HydrophobicContact CB-CD2 3.91Å; M291-L338 HydrophobicContact CB-CG 4.31Å; M291-L338 HydrophobicContact CG-CD2 3.99Å; M291-L338 HydrophobicContact CG-CG 4.31Å; M291-L338 HydrophobicContact SD-CD1 4.04Å; M291-L338 HydrophobicContact SD-CD2 4.27Å; M291-L338 HydrophobicContact SD-CG 3.94Å; V319-L338 HydrophobicContact CG2-CD1 3.63Å; A334-L338 WeakPolarHBondContact O-CB 3.4Å; A334-L338 WeakPolarHBondContact O-CG 3.37Å; A334-L338 PolarHBondContact O-N 3.1Å; Q335-L338 PolarHBondContact O-N 3.39Å; L338-K340 PolarHBondContact O-N 3.02Å; L338-K340 VanDerWaalsContact O-N 3.15Å; L338-T341 WeakPolarHBondContact O-CA 3.35Å; L338-T341 WeakPolarHBondContact O-CB 3.45Å; L338-T341 PolarHBondContact O-N 3.17Å; L338-S342 PolarHBondContact O-N 3.22Å; L338-L345 HydrophobicContact CB-CD1 4.08Å; L338-L345 HydrophobicContact CB-CD2 3.73Å
339E97.6Very high97.8Very high50 Ų5026.5 Ų26.523%0.23412%0.124CC..THydrogen-bonded Turntrans-63-21.5178.271.4158.6-168.700113.2Q335 L337 T341 S342 L345 P377 R404Q335-E339 WeakPolarHBondContact O-CB 3.27Å; Q335-E339 WeakPolarHBondContact O-CG 3.45Å; Q335-E339 PolarHBondContact O-N 3.13Å; L337-E339 PolarHBondContact O-N 3.27Å; E339-T341 PolarHBondContact O-N 3.28Å; E339-S342 WeakPolarHBondContact CA-O 3.4Å; E339-L345 HydrophobicContact CB-CD1 4.45Å; E339-P377 HydrophobicContact CB-CB 4.32Å; E339-P377 HydrophobicContact CB-CG 3.74Å; E339-P377 VanDerWaalsContact OE2-CD 3.26Å; E339-P377 WeakPolarHBondContact OE2-CD 3.33Å; E339-R404 IonicContact OE2-CZ 3.15Å; E339-R404 IonicContact OE2-NH1 2.67Å; E339-R404 IonicContact OE2-NH2 2.72Å; E339-R404 PolarHBondContact OE2-NH2 3.4Å
340K97.2Very high97.9Very high121 Ų12127 Ų2753%0.52613%0.128SC..THydrogen-bonded Turntrans-69.4-24.4173.5-59.6169.9-174.1166.10111.6P293 D336 L337 L338P293-K340 HydrophobicContact CG-CB 3.63Å; P293-K340 HydrophobicContact CG-CD 4.27Å; D336-K340 VanDerWaalsContact O-CE 3.26Å; D336-K340 WeakPolarHBondContact O-CE 3.36Å; L337-K340 WeakPolarHBondContact O-CB 3.39Å; L337-K340 PolarHBondContact O-N 2.52Å; L338-K340 PolarHBondContact O-N 3.02Å; L338-K340 VanDerWaalsContact O-N 3.15Å
341T97.1Very high97.8Very high7 Ų729 Ų294%0.04314%0.136CC..THydrogen-bonded Turntrans-99.9-41.2-177-58.30000112.1V250 L296 K313 P314 L338 E339V250-T341 HydrophobicContact CG2-CG2 4.33Å; L296-T341 HydrophobicContact CD1-CG2 3.8Å; K313-T341 VanDerWaalsContact CE-O 3.22Å; K313-T341 WeakPolarHBondContact CE-O 3.31Å; K313-T341 WeakPolarHBondContact CG-O 3.02Å; P314-T341 HydrophobicContact CB-CG2 4.21Å; P314-T341 HydrophobicContact CG-CG2 3.62Å; L338-T341 WeakPolarHBondContact O-CA 3.35Å; L338-T341 WeakPolarHBondContact O-CB 3.45Å; L338-T341 PolarHBondContact O-N 3.17Å; E339-T341 PolarHBondContact O-N 3.28Å
342S97.4Very high97.7Very high2 Ų229.1 Ų29.11%0.01414%0.136CC..  trans-141.5148.6-178.5-162.90000113P314 S315 Y316 C317 L338 E339 R344P314-S342 WeakPolarHBondContact O-CB 3.47Å; P314-S342 PolarHBondContact O-OG 3.33Å; S315-S342 VanDerWaalsContact C-OG 3.32Å; S315-S342 PolarHBondContact O-OG 2.82Å; Y316-S342 PolarHBondContact N-OG 2.97Å; C317-S342 WeakPolarHBondContact SG-CB 3.4Å; L338-S342 PolarHBondContact O-N 3.22Å; E339-S342 WeakPolarHBondContact CA-O 3.4Å; S342-R344 VanDerWaalsContact C-N 3.29Å; S342-R344 PolarHBondContact OG-N 3.39Å
343D97.7Very high97.7Very high46 Ų4625 Ų2525%0.24612%0.12CC..SBendtrans-87.51.8173.7-61-46.9000112.4K313 P377 T378 R404K313-D343 IonicContact NZ-OD1 3.14Å; K313-D343 PolarHBondContact NZ-OD1 3.14Å; K313-D343 IonicContact NZ-OD2 3.42Å; K313-D343 PolarHBondContact NZ-OD2 2.96Å; D343-P377 WeakPolarHBondContact O-CB 3.48Å; D343-T378 PolarHBondContact O-N 2.99Å; D343-R404 HydrophobicContact CB-CB 4.17Å; D343-R404 IonicContact OD1-NE 2.72Å; D343-R404 PolarHBondContact OD1-NE 3.13Å
344R98.4Very high97.7Very high40 Ų4021.8 Ų21.815%0.15111%0.105CC..EExtended strand (participates in β ladder)trans-129.9106.8178.8-67.1178.2-178.71504.6110C242 Y316 C317 S342 T378 F380 G405C242-R344 PolarHBondContact O-NH1 3.33Å; Y316-R344 WeakPolarHBondContact CA-O 3.49Å; C317-R344 PolarHBondContact N-O 3.02Å; S342-R344 VanDerWaalsContact C-N 3.29Å; S342-R344 PolarHBondContact OG-N 3.39Å; R344-T378 WeakPolarHBondContact CA-O 3.45Å; R344-F380 HydrophobicContact CB-CE2 4.33Å; R344-F380 HydrophobicContact CG-CE2 4.49Å; R344-G405 PolarHBondContact NE-O 3.2Å; R344-G405 PolarHBondContact NH2-O 3.04Å
345L98.7Very high97.8Very high1 Ų121.8 Ų21.81%0.00511%0.105CC..EExtended strand (participates in β ladder)trans-112.1133.9-178.4-52.3-173.4000109.4C317 Q335 L338 E339 F347 P377 T378 V379 F380C317-L345 HydrophobicContact CB-CD2 3.82Å; C317-L345 CarbonylContact O-C 3.54Å; C317-L345 WeakPolarHBondContact O-CA 3.24Å; Q335-L345 HydrophobicContact CB-CD1 4.2Å; Q335-L345 HydrophobicContact CG-CD1 3.85Å; L338-L345 HydrophobicContact CB-CD1 4.08Å; L338-L345 HydrophobicContact CB-CD2 3.73Å; E339-L345 HydrophobicContact CB-CD1 4.45Å; L345-F347 HydrophobicContact CB-CE2 4.48Å; L345-P377 HydrophobicContact CD1-CB 4.41Å; L345-P377 HydrophobicContact CD1-CG 3.58Å; L345-P377 HydrophobicContact CG-CB 4.24Å; L345-P377 HydrophobicContact CG-CG 3.91Å; L345-T378 PolarHBondContact N-O 3.11Å; L345-V379 CarbonylContact O-C 3.56Å; L345-V379 VanDerWaalsContact O-CA 3.31Å; L345-V379 WeakPolarHBondContact O-CA 3.1Å; L345-F380 WeakPolarHBondContact O-CD2 3.45Å; L345-F380 PolarHBondContact O-N 2.99Å
346H98.8Very high97.7Very high2 Ų223.5 Ų23.51%0.00911%0.111CC..EExtended strand (participates in β ladder)trans-123.2117.7176.5176-168.6000109.4N235 Y316 C317 V318 V319 F380 T382N235-H346 PolarHBondContact OD1-CE1 2.98Å; N235-H346 PolarHBondContact OD1-NE2 2.94Å; Y316-H346 HydrophobicContact CE2-CB 3.47Å; Y316-H346 VanDerWaalsContact CE2-CB 3.47Å; Y316-H346 AromaticContact CE2-ND1 3.91Å; Y316-H346 AromaticContact CZ-ND1 3.64Å; Y316-H346 PolarHBondContact OH-ND1 3.05Å; C317-H346 PolarHBondContact O-N 3.19Å; V318-H346 CarbonylContact C-O 3.57Å; V318-H346 VanDerWaalsContact CA-O 3.23Å; V318-H346 WeakPolarHBondContact CA-O 3.41Å; V318-H346 HydrophobicContact CB-CB 4.26Å; V318-H346 HydrophobicContact CG2-CB 4.15Å; V318-H346 WeakPolarHBondContact CG2-O 3.26Å; V319-H346 PolarHBondContact N-O 2.79Å; H346-F380 WeakPolarHBondContact CA-O 3.09Å; H346-F380 HydrophobicContact CB-CB 4.08Å; H346-T382 WeakPolarHBondContact NE2-CG2 3.38Å; H346-T382 PolarHBondContact NE2-OG1 3.14Å
347F98.7Very high97.7Very high3 Ų321.3 Ų21.31%0.01310%0.098CC..EExtended strand (participates in β ladder)trans-93.1110.7167.3-66.7-89.7000108.3V319 N321 A331 A334 Q335 L345 E349 A366 V379 F380 A381 T382V319-F347 HydrophobicContact CB-CD1 4.45Å; V319-F347 CarbonylContact O-C 3.47Å; V319-F347 WeakPolarHBondContact O-CA 3.49Å; N321-F347 HydrophobicContact CB-CD1 3.99Å; A331-F347 HydrophobicContact CB-CE1 4.1Å; A331-F347 HydrophobicContact CB-CZ 4.42Å; A334-F347 HydrophobicContact CB-CE1 4.32Å; Q335-F347 HydrophobicContact CB-CE2 4.48Å; Q335-F347 HydrophobicContact CB-CZ 4.23Å; L345-F347 HydrophobicContact CB-CE2 4.48Å; F347-E349 VanDerWaalsContact C-N 3.34Å; F347-E349 HydrophobicContact CB-CG 3.77Å; F347-E349 PolarHBondContact O-N 3.32Å; F347-A366 HydrophobicContact CB-CB 3.74Å; F347-A366 HydrophobicContact CD2-CB 3.64Å; F347-A366 HydrophobicContact CE2-CB 4.47Å; F347-A366 HydrophobicContact CG-CB 3.82Å; F347-V379 HydrophobicContact CD2-CG1 3.7Å; F347-V379 HydrophobicContact CE2-CG1 3.92Å; F347-F380 PolarHBondContact N-O 3.06Å; F347-A381 WeakPolarHBondContact O-CA 3.28Å; F347-T382 PolarHBondContact O-N 3.33Å
348D98.6Very high97.7Very high7 Ų720.4 Ų20.44%0.0379%0.093CC..EExtended strand (participates in β ladder)trans-7693171.5-170.3-1.8000109N235 V319 N321 A350 T382N235-D348 PolarHBondContact ND2-OD2 2.68Å; V319-D348 PolarHBondContact O-N 3.23Å; N321-D348 PolarHBondContact N-O 3.25Å; D348-A350 VanDerWaalsContact C-N 3.32Å; D348-A350 WeakPolarHBondContact OD1-CB 3.44Å; D348-A350 PolarHBondContact OD1-N 2.94Å; D348-T382 WeakPolarHBondContact CA-OG1 3.41Å; D348-T382 PolarHBondContact OD1-OG1 2.75Å
349E98.5Very high97.7Very high2 Ų224.7 Ų24.71%0.00912%0.121CC..  trans-98.133.7-176-57.8-162.2144.800112.7N321 F347 W351 Y352 Y365 A366 A381 T382 H383N321-E349 HydrophobicContact CB-CG 4.39Å; N321-E349 PolarHBondContact ND2-OE1 3.16Å; N321-E349 VanDerWaalsContact ND2-OE1 3.13Å; N321-E349 WeakPolarHBondContact O-CA 3.45Å; N321-E349 WeakPolarHBondContact O-CB 3.16Å; N321-E349 VanDerWaalsContact O-CG 3.25Å; N321-E349 WeakPolarHBondContact O-CG 3.3Å; F347-E349 VanDerWaalsContact C-N 3.34Å; F347-E349 HydrophobicContact CB-CG 3.77Å; F347-E349 PolarHBondContact O-N 3.32Å; E349-W351 PolarHBondContact O-N 3.24Å; E349-Y352 PolarHBondContact O-N 2.9Å; E349-Y365 VanDerWaalsContact OE1-CA 3.29Å; E349-Y365 WeakPolarHBondContact OE1-CA 3.29Å; E349-A366 WeakPolarHBondContact OE1-CB 3.47Å; E349-A366 PolarHBondContact OE1-N 3.25Å; E349-A381 HydrophobicContact CG-CB 4.48Å; E349-T382 CarbonylContact C-O 3.54Å; E349-T382 VanDerWaalsContact CA-O 3.24Å; E349-T382 WeakPolarHBondContact CA-O 3.42Å; E349-T382 PolarHBondContact N-O 3.44Å; E349-H383 VanDerWaalsContact CB-CD2 3.46Å; E349-H383 WeakPolarHBondContact CB-CD2 3.45Å; E349-H383 PolarHBondContact O-CD2 3.09Å; E349-H383 IonicContact OE2-CD2 2.81Å; E349-H383 IonicContact OE2-CE1 3.66Å; E349-H383 IonicContact OE2-NE2 3.62Å; E349-H383 PolarHBondContact OE2-NE2 3.19Å
350A97.6Very high97.7Very high10 Ų1022.4 Ų22.48%0.08311%0.111CC..THydrogen-bonded Turntrans-51.7-36.3-176.600000113.2T231 D348 T382 S384T231-A350 HydrophobicContact CG2-CB 4.18Å; D348-A350 VanDerWaalsContact C-N 3.32Å; D348-A350 WeakPolarHBondContact OD1-CB 3.44Å; D348-A350 PolarHBondContact OD1-N 2.94Å; A350-T382 PolarHBondContact N-O 2.93Å; A350-S384 WeakPolarHBondContact CB-OG 3.37Å; A350-S384 VanDerWaalsContact O-CB 3.3Å; A350-S384 WeakPolarHBondContact O-CB 3.46Å; A350-S384 PolarHBondContact O-N 3.32Å
351W96.3Very high97.7Very high46 Ų4616.7 Ų16.717%0.1749%0.086CC..THydrogen-bonded Turntrans-99.212.2179.4-68.4114000114Y324 E349 Y354 K387 L388 K536 L582Y324-W351 HydrophobicContact CD2-CZ2 4.19Å; Y324-W351 AromaticContact CD2-NE1 3.52Å; Y324-W351 AromaticContact CE2-CE2 3.89Å; Y324-W351 AromaticContact CE2-CZ2 3.59Å; Y324-W351 HydrophobicContact CE2-CZ2 3.59Å; Y324-W351 AromaticContact CE2-NE1 3.84Å; E349-W351 PolarHBondContact O-N 3.24Å; W351-Y354 VanDerWaalsContact O-CE1 3.28Å; W351-Y354 WeakPolarHBondContact O-CE1 3.49Å; W351-Y354 PolarHBondContact O-OH 2.79Å; W351-Y354 VanDerWaalsContact O-OH 3.14Å; W351-K387 HydrophobicContact CD2-CD 3.77Å; W351-K387 HydrophobicContact CE3-CB 3.87Å; W351-K387 HydrophobicContact CE3-CD 3.68Å; W351-K387 HydrophobicContact CE3-CG 4.28Å; W351-K387 HydrophobicContact CH2-CD 3.78Å; W351-K387 HydrophobicContact CH2-CG 4.29Å; W351-K387 HydrophobicContact CZ2-CD 3.84Å; W351-K387 HydrophobicContact CZ3-CB 3.78Å; W351-K387 HydrophobicContact CZ3-CD 3.68Å; W351-K387 HydrophobicContact CZ3-CG 4Å; W351-L388 HydrophobicContact CB-CD1 4.39Å; W351-L388 HydrophobicContact CE3-CD1 3.7Å; W351-L388 HydrophobicContact CE3-CG 4.07Å; W351-L388 HydrophobicContact CZ3-CD1 4.44Å; W351-L388 HydrophobicContact CZ3-CG 4.45Å; W351-L388 VanDerWaalsContact O-CD1 3.26Å; W351-L388 WeakPolarHBondContact O-CD1 3.48Å; W351-K536 PolarHBondContact O-NZ 2.82Å; W351-L582 HydrophobicContact CE3-CD1 4.18Å; W351-L582 HydrophobicContact CH2-CD1 3.76Å; W351-L582 HydrophobicContact CZ3-CD1 3.4Å; W351-L582 VanDerWaalsContact CZ3-CD1 3.4Å
352Y96.9Very high97.7Very high1 Ų118.3 Ų18.30%0.00410%0.1CC..  trans-139.518.8-164.4-152.9-132.9000114.4N321 C322 C328 E349 Y354 A355 Y361 H364N321-Y352 WeakPolarHBondContact O-CB 3.4Å; C322-Y352 HydrophobicContact CB-CD2 4.41Å; C322-Y352 HydrophobicContact CB-CG 4.48Å; C328-Y352 HydrophobicContact CB-CE1 4.46Å; C328-Y352 WeakPolarHBondContact SG-CE2 3.38Å; C328-Y352 PolarHBondContact SG-OH 3.38Å; E349-Y352 PolarHBondContact O-N 2.9Å; Y352-Y354 AromaticContact CD2-CE2 3.89Å; Y352-Y354 HydrophobicContact CD2-CE2 3.89Å; Y352-Y354 AromaticContact CD2-CZ 3.84Å; Y352-Y354 HydrophobicContact CE2-CE2 4.04Å; Y352-Y354 PolarHBondContact O-N 2.78Å; Y352-A355 HydrophobicContact CD1-CB 3.59Å; Y352-A355 HydrophobicContact CD2-CB 3.98Å; Y352-A355 HydrophobicContact CE1-CB 3.33Å; Y352-A355 HydrophobicContact CE2-CB 3.74Å; Y352-A355 HydrophobicContact CG-CB 3.9Å; Y352-A355 VanDerWaalsContact CZ-CB 3.42Å; Y352-A355 WeakPolarHBondContact O-CB 3.5Å; Y352-A355 PolarHBondContact O-N 3.05Å; Y352-A355 VanDerWaalsContact O-N 3.13Å; Y352-Y361 AromaticContact CE2-CD1 3.99Å; Y352-Y361 HydrophobicContact CE2-CD1 3.99Å; Y352-Y361 HydrophobicContact CE2-CE1 4.1Å; Y352-Y361 HydrophobicContact CE2-CG 4.44Å; Y352-Y361 AromaticContact CZ-CD1 3.87Å; Y352-Y361 WeakPolarHBondContact OH-CD1 3.46Å; Y352-H364 VanDerWaalsContact CE1-O 3.26Å; Y352-H364 WeakPolarHBondContact CE1-O 3.5Å
353G96.9Very high97.7Very high7 Ų721.3 Ų21.37%0.07212%0.116CC..THydrogen-bonded Turntrans-62.9-10.6-179.400000116F219 F357F219-G353 WeakPolarHBondContact CE1-O 3.39Å; G353-F357 WeakPolarHBondContact O-CE2 3.37Å
354Y97.8Very high97.7Very high5 Ų519.1 Ų19.12%0.0210%0.104CC..THydrogen-bonded Turntrans-92-11.9177.349.6-91.8000114W351 Y352 R356 F357 Y361 L388 D533 I535 K536W351-Y354 VanDerWaalsContact O-CE1 3.28Å; W351-Y354 WeakPolarHBondContact O-CE1 3.49Å; W351-Y354 PolarHBondContact O-OH 2.79Å; W351-Y354 VanDerWaalsContact O-OH 3.14Å; Y352-Y354 AromaticContact CD2-CE2 3.89Å; Y352-Y354 HydrophobicContact CD2-CE2 3.89Å; Y352-Y354 AromaticContact CD2-CZ 3.84Å; Y352-Y354 HydrophobicContact CE2-CE2 4.04Å; Y352-Y354 PolarHBondContact O-N 2.78Å; Y354-R356 VanDerWaalsContact C-N 3.28Å; Y354-R356 PolarHBondContact O-N 2.84Å; Y354-F357 VanDerWaalsContact O-CD2 3.31Å; Y354-F357 WeakPolarHBondContact O-CD2 3.33Å; Y354-F357 PolarHBondContact O-N 2.82Å; Y354-Y361 AromaticContact CD2-CE2 3.98Å; Y354-Y361 HydrophobicContact CD2-CE2 3.98Å; Y354-Y361 HydrophobicContact CE2-CE2 4.08Å; Y354-Y361 AromaticContact CE2-CZ 3.94Å; Y354-L388 HydrophobicContact CD1-CB 3.73Å; Y354-L388 HydrophobicContact CE1-CB 3.56Å; Y354-L388 HydrophobicContact CE1-CD1 3.56Å; Y354-L388 HydrophobicContact CE1-CG 4.14Å; Y354-D533 PolarHBondContact OH-OD2 2.9Å; Y354-I535 HydrophobicContact CD1-CD1 4.47Å; Y354-I535 HydrophobicContact CD2-CD1 4.3Å; Y354-I535 HydrophobicContact CE1-CD1 3.85Å; Y354-I535 HydrophobicContact CE2-CD1 3.6Å; Y354-I535 HydrophobicContact CE2-CG1 4.49Å; Y354-I535 WeakPolarHBondContact OH-CD1 3.45Å; Y354-K536 WeakPolarHBondContact OH-CE 3.28Å; Y354-K536 PolarHBondContact OH-NZ 3.1Å
355A98.1Very high97.7Very high0 Ų018.7 Ų18.70%010%0.103CC..G310 helixtrans-59.1-37.2-165.100000113.5Y352 F357 N358 Y361 Y365Y352-A355 HydrophobicContact CD1-CB 3.59Å; Y352-A355 HydrophobicContact CD2-CB 3.98Å; Y352-A355 HydrophobicContact CE1-CB 3.33Å; Y352-A355 HydrophobicContact CE2-CB 3.74Å; Y352-A355 HydrophobicContact CG-CB 3.9Å; Y352-A355 VanDerWaalsContact CZ-CB 3.42Å; Y352-A355 WeakPolarHBondContact O-CB 3.5Å; Y352-A355 PolarHBondContact O-N 3.05Å; Y352-A355 VanDerWaalsContact O-N 3.13Å; A355-F357 PolarHBondContact O-N 3.37Å; A355-F357 VanDerWaalsContact O-N 3.13Å; A355-N358 PolarHBondContact O-N 2.91Å; A355-Y361 HydrophobicContact CB-CD2 4.27Å; A355-Y361 HydrophobicContact CB-CG 4.22Å; A355-Y361 WeakPolarHBondContact O-CD2 3.35Å; A355-Y365 HydrophobicContact CB-CD1 3.95Å; A355-Y365 HydrophobicContact CB-CG 3.93Å
356R97.2Very high97.7Very high50 Ų5018.9 Ų18.919%0.18911%0.105CC..G310 helixtrans-58.6-27.3178.9179.1172.9174.982.25.2113.6V218 F219 Y354 Y365 M367 G369 E370V218-R356 PolarHBondContact O-NE 3.44Å; F219-R356 VanDerWaalsContact C-NE 3.32Å; F219-R356 WeakPolarHBondContact O-CD 3.45Å; F219-R356 PolarHBondContact O-NE 3.27Å; Y354-R356 VanDerWaalsContact C-N 3.28Å; Y354-R356 PolarHBondContact O-N 2.84Å; R356-Y365 HydrophobicContact CB-CD2 4.09Å; R356-Y365 HydrophobicContact CB-CE2 3.68Å; R356-Y365 HydrophobicContact CG-CE2 3.91Å; R356-M367 PolarHBondContact NH1-O 3.16Å; R356-G369 PolarHBondContact NH1-O 3.41Å; R356-G369 PolarHBondContact NH2-O 3.26Å; R356-E370 IonicContact NH2-OE1 2.77Å; R356-E370 PolarHBondContact NH2-OE1 3.05Å
357F97.6Very high97.6Very high22 Ų2219 Ų1910%0.09611%0.105CC..G310 helixtrans-89.7-1.9-169.4-48-65.7000113.6V218 F219 G353 Y354 A355 M439 L445 T448V218-F357 HydrophobicContact CG1-CE1 3.76Å; V218-F357 HydrophobicContact CG1-CZ 4.11Å; F219-F357 HydrophobicContact CD1-CE2 4.35Å; F219-F357 AromaticContact CD1-CZ 3.89Å; F219-F357 HydrophobicContact CD1-CZ 3.89Å; F219-F357 HydrophobicContact CD2-CZ 4.27Å; F219-F357 AromaticContact CE1-CE2 3.77Å; F219-F357 HydrophobicContact CE1-CE2 3.77Å; F219-F357 AromaticContact CE1-CZ 3.64Å; F219-F357 HydrophobicContact CE1-CZ 3.64Å; F219-F357 HydrophobicContact CE2-CZ 4.01Å; F219-F357 HydrophobicContact CG-CZ 4.21Å; F219-F357 AromaticContact CZ-CE2 3.95Å; F219-F357 HydrophobicContact CZ-CE2 3.95Å; F219-F357 AromaticContact CZ-CZ 3.7Å; F219-F357 HydrophobicContact CZ-CZ 3.7Å; G353-F357 WeakPolarHBondContact O-CE2 3.37Å; Y354-F357 VanDerWaalsContact O-CD2 3.31Å; Y354-F357 WeakPolarHBondContact O-CD2 3.33Å; Y354-F357 PolarHBondContact O-N 2.82Å; A355-F357 PolarHBondContact O-N 3.37Å; A355-F357 VanDerWaalsContact O-N 3.13Å; F357-M439 HydrophobicContact CD1-CB 4.02Å; F357-M439 WeakPolarHBondContact CD1-O 3.45Å; F357-M439 HydrophobicContact CD2-CB 3.95Å; F357-M439 HydrophobicContact CD2-CG 3.89Å; F357-M439 HydrophobicContact CD2-SD 3.57Å; F357-M439 VanDerWaalsContact CD2-SD 3.57Å; F357-M439 HydrophobicContact CE1-CB 3.71Å; F357-M439 HydrophobicContact CE2-CB 3.64Å; F357-M439 HydrophobicContact CE2-CG 3.59Å; F357-M439 HydrophobicContact CE2-SD 3.9Å; F357-M439 HydrophobicContact CG-CB 4.16Å; F357-M439 HydrophobicContact CG-SD 4.16Å; F357-M439 HydrophobicContact CZ-CB 3.52Å; F357-M439 HydrophobicContact CZ-CG 3.98Å; F357-L445 VanDerWaalsContact O-CA 3.29Å; F357-L445 WeakPolarHBondContact O-CA 3.44Å; F357-T448 HydrophobicContact CB-CG2 4.13Å
358N97.5Very high97.5Very high4 Ų420.8 Ų20.82%0.02111%0.112CC..  trans-129.5126.7175.6-160.3-65.8000112.2A355 I360 Y361 T448 Q449 I452A355-N358 PolarHBondContact O-N 2.91Å; N358-I360 HydrophobicContact CB-CG2 4.21Å; N358-I360 PolarHBondContact O-N 3.06Å; N358-I360 WeakPolarHBondContact OD1-CB 3.11Å; N358-I360 VanDerWaalsContact OD1-CG2 3.27Å; N358-I360 WeakPolarHBondContact OD1-CG2 3.25Å; N358-I360 PolarHBondContact OD1-N 3.24Å; N358-Y361 HydrophobicContact CB-CD2 3.82Å; N358-Y361 HydrophobicContact CB-CE2 3.91Å; N358-Y361 PolarHBondContact O-N 2.9Å; N358-Y361 VanDerWaalsContact O-N 3.11Å; N358-T448 WeakPolarHBondContact CB-OG1 3.47Å; N358-T448 PolarHBondContact ND2-OG1 3.14Å; N358-Q449 PolarHBondContact ND2-OE1 2.6Å; N358-I452 HydrophobicContact CB-CD1 4.25Å; N358-I452 WeakPolarHBondContact ND2-CD1 3.44Å
359P97Very high97.2Very high93 Ų9322.5 Ų22.560%0.60413%0.131SC*.G310 helixtrans-55.7-23.4178.1-27.434.6000115.3Y361 A362 L445P359-Y361 PolarHBondContact O-N 2.7Å; P359-Y361 VanDerWaalsContact O-N 3.13Å; P359-A362 WeakPolarHBondContact O-CB 3.27Å; P359-A362 PolarHBondContact O-N 3.13Å; P359-A362 VanDerWaalsContact O-N 3.08Å; P359-L445 HydrophobicContact CG-CD1 4.47Å
360I97.4Very high97Very high2 Ų227.1 Ų27.11%0.0115%0.153CC..G310 helixtrans-60.4-22.5178.1-156168000112.9N358 I452 Q508 M531 P534N358-I360 HydrophobicContact CB-CG2 4.21Å; N358-I360 PolarHBondContact O-N 3.06Å; N358-I360 WeakPolarHBondContact OD1-CB 3.11Å; N358-I360 VanDerWaalsContact OD1-CG2 3.27Å; N358-I360 WeakPolarHBondContact OD1-CG2 3.25Å; N358-I360 PolarHBondContact OD1-N 3.24Å; I360-I452 HydrophobicContact CG2-CD1 3.86Å; I360-Q508 HydrophobicContact CG1-CB 4.36Å; I360-Q508 WeakPolarHBondContact O-CB 3.43Å; I360-Q508 VanDerWaalsContact O-CG 3.26Å; I360-Q508 WeakPolarHBondContact O-CG 3.27Å; I360-Q508 PolarHBondContact O-NE2 3.48Å; I360-M531 WeakPolarHBondContact O-CE 3.17Å; I360-P534 HydrophobicContact CD1-CG 4.11Å
361Y98Very high96.9Very high1 Ų128.1 Ų28.10%0.00416%0.159CC..G310 helixtrans-9911.8179.9-54.3-64000113.3Y352 Y354 A355 N358 P359 D363 H364 Y365 I452 M531 D533Y352-Y361 AromaticContact CE2-CD1 3.99Å; Y352-Y361 HydrophobicContact CE2-CD1 3.99Å; Y352-Y361 HydrophobicContact CE2-CE1 4.1Å; Y352-Y361 HydrophobicContact CE2-CG 4.44Å; Y352-Y361 AromaticContact CZ-CD1 3.87Å; Y352-Y361 WeakPolarHBondContact OH-CD1 3.46Å; Y354-Y361 AromaticContact CD2-CE2 3.98Å; Y354-Y361 HydrophobicContact CD2-CE2 3.98Å; Y354-Y361 HydrophobicContact CE2-CE2 4.08Å; Y354-Y361 AromaticContact CE2-CZ 3.94Å; A355-Y361 HydrophobicContact CB-CD2 4.27Å; A355-Y361 HydrophobicContact CB-CG 4.22Å; A355-Y361 WeakPolarHBondContact O-CD2 3.35Å; N358-Y361 HydrophobicContact CB-CD2 3.82Å; N358-Y361 HydrophobicContact CB-CE2 3.91Å; N358-Y361 PolarHBondContact O-N 2.9Å; N358-Y361 VanDerWaalsContact O-N 3.11Å; P359-Y361 PolarHBondContact O-N 2.7Å; P359-Y361 VanDerWaalsContact O-N 3.13Å; Y361-D363 PolarHBondContact O-N 3.49Å; Y361-H364 WeakPolarHBondContact O-CB 3.4Å; Y361-H364 PolarHBondContact O-N 2.98Å; Y361-Y365 WeakPolarHBondContact O-CD1 3.34Å; Y361-Y365 WeakPolarHBondContact O-CE1 3.41Å; Y361-I452 HydrophobicContact CE2-CD1 4.14Å; Y361-M531 HydrophobicContact CD1-CE 4.03Å; Y361-M531 HydrophobicContact CD1-SD 4.26Å; Y361-M531 HydrophobicContact CE1-CE 4.35Å; Y361-D533 PolarHBondContact OH-OD1 2.85Å; Y361-D533 VanDerWaalsContact OH-OD1 3.1Å
362A96.9Very high96.6Very high41 Ų4129.6 Ų29.634%0.33919%0.188SC..THydrogen-bonded Turntrans-46.2136.6178.300000111.6P359 H364 Q508P359-A362 WeakPolarHBondContact O-CB 3.27Å; P359-A362 PolarHBondContact O-N 3.13Å; P359-A362 VanDerWaalsContact O-N 3.08Å; A362-H364 PolarHBondContact O-N 3.39Å; A362-H364 PolarHBondContact O-ND1 3.05Å; A362-Q508 PolarHBondContact O-NE2 3.44Å
363D97.3Very high96.4Very high65 Ų6536 Ų3635%0.34822%0.222SC..THydrogen-bonded Turntrans64.2-5.7-174.9-67.8-31000117.6A331 K332 Y361A331-D363 PolarHBondContact N-O 3.43Å; K332-D363 HydrophobicContact CB-CB 4.29Å; K332-D363 PolarHBondContact N-O 3.27Å; Y361-D363 PolarHBondContact O-N 3.49Å
364H98Very high96.3Very high0 Ų037.8 Ų37.80%023%0.229CC..SBendtrans-100.83.4-172.2-70.974000116N321 C328 Y329 N330 Y352 Y361 A362 Q508 M531N321-H364 PolarHBondContact ND2-O 2.94Å; C328-H364 HydrophobicContact CB-CB 4.29Å; Y329-H364 CarbonylContact O-C 3.55Å; Y329-H364 WeakPolarHBondContact O-CA 3.12Å; Y329-H364 VanDerWaalsContact O-CB 3.3Å; Y329-H364 WeakPolarHBondContact O-CB 3.37Å; Y329-H364 PolarHBondContact O-CD2 3.21Å; Y329-H364 VanDerWaalsContact O-O 3.14Å; N330-H364 PolarHBondContact N-CD2 2.91Å; Y352-H364 VanDerWaalsContact CE1-O 3.26Å; Y352-H364 WeakPolarHBondContact CE1-O 3.5Å; Y361-H364 WeakPolarHBondContact O-CB 3.4Å; Y361-H364 PolarHBondContact O-N 2.98Å; A362-H364 PolarHBondContact O-N 3.39Å; A362-H364 PolarHBondContact O-ND1 3.05Å; H364-Q508 PolarHBondContact ND1-NE2 3.27Å; H364-M531 HydrophobicContact CB-SD 4.07Å; H364-M531 VanDerWaalsContact CD2-CG 3.46Å; H364-M531 WeakPolarHBondContact CD2-CG 3.46Å
365Y98.2Very high96Very high30 Ų3044.5 Ų44.512%0.11827%0.265CS..SBendtrans-126.3166.6176.757.7-84.4000111.2A331 E349 A355 R356 Y361 M367 R368A331-Y365 WeakPolarHBondContact CB-O 3.48Å; E349-Y365 VanDerWaalsContact OE1-CA 3.29Å; E349-Y365 WeakPolarHBondContact OE1-CA 3.29Å; A355-Y365 HydrophobicContact CB-CD1 3.95Å; A355-Y365 HydrophobicContact CB-CG 3.93Å; R356-Y365 HydrophobicContact CB-CD2 4.09Å; R356-Y365 HydrophobicContact CB-CE2 3.68Å; R356-Y365 HydrophobicContact CG-CE2 3.91Å; Y361-Y365 WeakPolarHBondContact O-CD1 3.34Å; Y361-Y365 WeakPolarHBondContact O-CE1 3.41Å; Y365-M367 VanDerWaalsContact CE2-O 3.29Å; Y365-M367 WeakPolarHBondContact CE2-O 3.45Å; Y365-R368 HydrophobicContact CD2-CG 4.06Å; Y365-R368 HydrophobicContact CE2-CB 4.36Å; Y365-R368 HydrophobicContact CE2-CG 3.92Å; Y365-R368 HydrophobicContact CG-CG 4.47Å; Y365-R368 WeakPolarHBondContact O-CD 3.19Å; Y365-R368 WeakPolarHBondContact O-CG 3.47Å; Y365-R368 PolarHBondContact O-NH1 3.01Å
366A98Very high95.9Very high6 Ų644.6 Ų44.65%0.0527%0.266CS..SBendtrans-77-49.5-171.100000114.4F347 E349 R368 V379 A381F347-A366 HydrophobicContact CB-CB 3.74Å; F347-A366 HydrophobicContact CD2-CB 3.64Å; F347-A366 HydrophobicContact CE2-CB 4.47Å; F347-A366 HydrophobicContact CG-CB 3.82Å; E349-A366 WeakPolarHBondContact OE1-CB 3.47Å; E349-A366 PolarHBondContact OE1-N 3.25Å; A366-R368 PolarHBondContact O-N 3.13Å; A366-R368 PolarHBondContact O-NH1 3.43Å; A366-V379 HydrophobicContact CB-CG1 4.14Å; A366-A381 HydrophobicContact CB-CB 3.87Å
367M97.7Very high96Very high3 Ų342.2 Ų42.22%0.01526%0.257CS..SBendtrans-81.758.6-175.1-64.8-63.3127.700112.7F219 A221 R356 Y365 V379 A381 H399 R401F219-M367 VanDerWaalsContact O-CB 3.24Å; F219-M367 WeakPolarHBondContact O-CB 3.3Å; A221-M367 HydrophobicContact CB-SD 3.92Å; R356-M367 PolarHBondContact NH1-O 3.16Å; Y365-M367 VanDerWaalsContact CE2-O 3.29Å; Y365-M367 WeakPolarHBondContact CE2-O 3.45Å; M367-V379 HydrophobicContact CE-CB 4.31Å; M367-V379 HydrophobicContact CE-CG1 4.03Å; M367-V379 WeakPolarHBondContact CE-O 3.41Å; M367-A381 HydrophobicContact CE-CB 3.77Å; M367-A381 HydrophobicContact CG-CB 4.03Å; M367-H399 HydrophobicContact CE-CB 4.36Å; M367-H399 HydrophobicContact CG-CB 3.89Å; M367-H399 HydrophobicContact SD-CB 4.05Å; M367-R401 HydrophobicContact CE-CB 4.1Å; M367-R401 HydrophobicContact SD-CB 4.05Å
368R95.6Very high96Very high41 Ų4141.2 Ų41.216%0.15525%0.253CS..  trans-78.1152.6-178.9-56.3173.8-61.1-81.6-2.8111.7A331 Y365 A366 R401A331-R368 PolarHBondContact O-NH1 3.1Å; Y365-R368 HydrophobicContact CD2-CG 4.06Å; Y365-R368 HydrophobicContact CE2-CB 4.36Å; Y365-R368 HydrophobicContact CE2-CG 3.92Å; Y365-R368 HydrophobicContact CG-CG 4.47Å; Y365-R368 WeakPolarHBondContact O-CD 3.19Å; Y365-R368 WeakPolarHBondContact O-CG 3.47Å; Y365-R368 PolarHBondContact O-NH1 3.01Å; A366-R368 PolarHBondContact O-N 3.13Å; A366-R368 PolarHBondContact O-NH1 3.43Å; R368-R401 PolarHBondContact O-NH2 3.47Å
369G93.3Very high96.1Very high43 Ų4341.1 Ų41.144%0.44325%0.252SS..SBendtrans57.1-158.1176.200000113.3R356 R401R356-G369 PolarHBondContact NH1-O 3.41Å; R356-G369 PolarHBondContact NH2-O 3.26Å; G369-R401 PolarHBondContact O-NH2 3.29Å
370E94.7Very high96.2Very high99 Ų9936.7 Ų36.746%0.46322%0.223SC..  trans-100.9150176.4-65.9-53.2122.400111.6R356 G372 D373R356-E370 IonicContact NH2-OE1 2.77Å; R356-E370 PolarHBondContact NH2-OE1 3.05Å; E370-G372 VanDerWaalsContact C-N 3.27Å; E370-G372 PolarHBondContact O-N 3.34Å; E370-D373 PolarHBondContact O-N 3.07Å
371P93.7Very high96.2Very high32 Ų3236.6 Ų36.621%0.20822%0.223CC..G310 helixtrans-54.2-38.7-179-15.118.4000115.3D222 D373 H374D222-P371 WeakPolarHBondContact OD1-CB 3.45Å; P371-D373 PolarHBondContact O-N 3.22Å; P371-D373 VanDerWaalsContact O-N 3.16Å; P371-H374 PolarHBondContact O-N 3.38Å
372G91.5Very high96.3Very high77 Ų7736.6 Ų36.679%0.79422%0.223SC*.G310 helixtrans-64.7-18.5-177.200000115E370E370-G372 VanDerWaalsContact C-N 3.27Å; E370-G372 PolarHBondContact O-N 3.34Å
373D92.3Very high96.4Very high134 Ų13435 Ų3572%0.71721%0.208SC*.G310 helixtrans-91.7-4.1-177.1-61.2-35.3000113E370 P371E370-D373 PolarHBondContact O-N 3.07Å; P371-D373 PolarHBondContact O-N 3.22Å; P371-D373 VanDerWaalsContact O-N 3.16Å
374H94.9Very high96.4Very high46 Ų4632.1 Ų32.121%0.21319%0.194CC..  trans-89.9126.5-173.6-176.379.6000113.1P371 G376 P377 R401 E402P371-H374 PolarHBondContact O-N 3.38Å; H374-G376 PolarHBondContact NE2-N 2.78Å; H374-P377 PolarHBondContact CE1-O 3.41Å; H374-P377 PolarHBondContact NE2-O 2.97Å; H374-R401 HydrophobicContact CB-CG 3.9Å; H374-R401 WeakPolarHBondContact CD2-CG 3.33Å; H374-R401 VanDerWaalsContact CG-CG 3.41Å; H374-E402 PolarHBondContact CD2-O 3.08Å; H374-E402 VanDerWaalsContact CD2-O 3.28Å
375N92.1Very high96.4Very high146 Ų14632.2 Ų32.278%0.78119%0.194SC*.  trans-124.510.517764.25000113.6R404N375-R404 PolarHBondContact O-NH1 3.13Å
376G96.2Very high96.4Very high2 Ų233.6 Ų33.62%0.02120%0.201CC..SBendtrans-86.1-156.6-173.800000114.9H374 G403 R404H374-G376 PolarHBondContact NE2-N 2.78Å; G376-G403 WeakPolarHBondContact O-CA 3.35Å; G376-R404 PolarHBondContact O-N 3.47Å
377P98Very high96.2Very high0 Ų036.2 Ų36.20%021%0.212CC..BIsolated β-bridgetrans-69.7169.7171.834.6-39.2000110.8Q335 E339 D343 L345 H374 V379Q335-P377 HydrophobicContact CG-CG 4.32Å; E339-P377 HydrophobicContact CB-CB 4.32Å; E339-P377 HydrophobicContact CB-CG 3.74Å; E339-P377 VanDerWaalsContact OE2-CD 3.26Å; E339-P377 WeakPolarHBondContact OE2-CD 3.33Å; D343-P377 WeakPolarHBondContact O-CB 3.48Å; L345-P377 HydrophobicContact CD1-CB 4.41Å; L345-P377 HydrophobicContact CD1-CG 3.58Å; L345-P377 HydrophobicContact CG-CB 4.24Å; L345-P377 HydrophobicContact CG-CG 3.91Å; H374-P377 PolarHBondContact CE1-O 3.41Å; H374-P377 PolarHBondContact NE2-O 2.97Å; P377-V379 HydrophobicContact CG-CG2 4.28Å; P377-V379 PolarHBondContact O-N 2.66Å
378T98.5Very high96.2Very high1 Ų136.4 Ų36.41%0.00621%0.213CC..EExtended strand (participates in β ladder)trans-71.2127.1167.7-59.30000109D343 R344 L345 F380 V400 R401 G403 R404 A406D343-T378 PolarHBondContact O-N 2.99Å; R344-T378 WeakPolarHBondContact CA-O 3.45Å; L345-T378 PolarHBondContact N-O 3.11Å; T378-F380 HydrophobicContact CG2-CD2 4.48Å; T378-F380 HydrophobicContact CG2-CE1 4.39Å; T378-F380 HydrophobicContact CG2-CE2 3.75Å; T378-F380 HydrophobicContact CG2-CZ 3.68Å; T378-V400 HydrophobicContact CG2-CG1 4Å; T378-R401 WeakPolarHBondContact CA-O 3.4Å; T378-G403 PolarHBondContact OG1-N 2.96Å; T378-R404 PolarHBondContact N-O 3.42Å; T378-R404 PolarHBondContact OG1-O 3.11Å; T378-A406 WeakPolarHBondContact OG1-CA 3.47Å; T378-A406 PolarHBondContact OG1-N 3.23Å
379V98.6Very high96.2Very high1 Ų134.9 Ų34.91%0.00621%0.208CC..EExtended strand (participates in β ladder)trans-114.6129.7-179.3-174.90000109.5L345 F347 A366 M367 P377 V400 R401L345-V379 CarbonylContact O-C 3.56Å; L345-V379 VanDerWaalsContact O-CA 3.31Å; L345-V379 WeakPolarHBondContact O-CA 3.1Å; F347-V379 HydrophobicContact CD2-CG1 3.7Å; F347-V379 HydrophobicContact CE2-CG1 3.92Å; A366-V379 HydrophobicContact CB-CG1 4.14Å; M367-V379 HydrophobicContact CE-CB 4.31Å; M367-V379 HydrophobicContact CE-CG1 4.03Å; M367-V379 WeakPolarHBondContact CE-O 3.41Å; P377-V379 HydrophobicContact CG-CG2 4.28Å; P377-V379 PolarHBondContact O-N 2.66Å; V379-V400 WeakPolarHBondContact O-CA 3.42Å; V379-R401 HydrophobicContact CB-CB 4.21Å; V379-R401 PolarHBondContact N-O 3.24Å; V379-R401 PolarHBondContact O-N 3.48Å
380F98.8Very high96.4Very high1 Ų135.5 Ų35.50%0.00420%0.201CC..EExtended strand (participates in β ladder)trans-106.5139.5172-56.9-89.7000109.2I238 R344 L345 H346 F347 T378 H399 V400 I407 F412I238-F380 HydrophobicContact CD1-CB 3.91Å; I238-F380 HydrophobicContact CD1-CD1 4.31Å; I238-F380 HydrophobicContact CD1-CG 4.34Å; I238-F380 HydrophobicContact CG1-CB 4.5Å; I238-F380 HydrophobicContact CG1-CD1 4.04Å; I238-F380 HydrophobicContact CG1-CG 4.4Å; I238-F380 HydrophobicContact CG2-CB 4.27Å; I238-F380 HydrophobicContact CG2-CD1 3.99Å; I238-F380 HydrophobicContact CG2-CD2 4.01Å; I238-F380 HydrophobicContact CG2-CE1 4.4Å; I238-F380 HydrophobicContact CG2-CE2 4.39Å; I238-F380 HydrophobicContact CG2-CG 3.82Å; R344-F380 HydrophobicContact CB-CE2 4.33Å; R344-F380 HydrophobicContact CG-CE2 4.49Å; L345-F380 WeakPolarHBondContact O-CD2 3.45Å; L345-F380 PolarHBondContact O-N 2.99Å; H346-F380 WeakPolarHBondContact CA-O 3.09Å; H346-F380 HydrophobicContact CB-CB 4.08Å; F347-F380 PolarHBondContact N-O 3.06Å; T378-F380 HydrophobicContact CG2-CD2 4.48Å; T378-F380 HydrophobicContact CG2-CE1 4.39Å; T378-F380 HydrophobicContact CG2-CE2 3.75Å; T378-F380 HydrophobicContact CG2-CZ 3.68Å; F380-H399 CarbonylContact C-O 3.15Å; F380-H399 WeakPolarHBondContact CA-O 3.45Å; F380-V400 HydrophobicContact CD1-CB 4.44Å; F380-V400 HydrophobicContact CD1-CG1 4.22Å; F380-V400 HydrophobicContact CD1-CG2 3.61Å; F380-V400 HydrophobicContact CE1-CB 4.5Å; F380-V400 HydrophobicContact CE1-CG1 3.92Å; F380-V400 HydrophobicContact CE1-CG2 3.77Å; F380-I407 HydrophobicContact CZ-CD1 3.99Å; F380-F412 HydrophobicContact CD1-CE2 4.27Å; F380-F412 HydrophobicContact CE1-CD2 4.28Å; F380-F412 AromaticContact CE1-CE2 3.68Å; F380-F412 HydrophobicContact CE1-CE2 3.68Å
381A98.7Very high96.5Very high0 Ų031.8 Ų31.80%019%0.187CC..EExtended strand (participates in β ladder)trans-126133.4166.300000109.3F347 E349 A366 M367 H399F347-A381 WeakPolarHBondContact O-CA 3.28Å; E349-A381 HydrophobicContact CG-CB 4.48Å; A366-A381 HydrophobicContact CB-CB 3.87Å; M367-A381 HydrophobicContact CE-CB 3.77Å; M367-A381 HydrophobicContact CG-CB 4.03Å; A381-H399 HydrophobicContact CB-CB 4.3Å; A381-H399 PolarHBondContact N-O 3.45Å; A381-H399 PolarHBondContact O-N 2.85Å
382T98.8Very high96.7Very high0 Ų034.5 Ų34.50%020%0.199CC..EExtended strand (participates in β ladder)trans-112.2125.5175.144.40000110.8N235 I238 H346 F347 D348 E349 A350 Y397 I398N235-T382 WeakPolarHBondContact OD1-CG2 3.33Å; N235-T382 PolarHBondContact OD1-OG1 3.38Å; N235-T382 VanDerWaalsContact OD1-OG1 3.08Å; I238-T382 HydrophobicContact CD1-CG2 3.26Å; H346-T382 WeakPolarHBondContact NE2-CG2 3.38Å; H346-T382 PolarHBondContact NE2-OG1 3.14Å; F347-T382 PolarHBondContact O-N 3.33Å; D348-T382 WeakPolarHBondContact CA-OG1 3.41Å; D348-T382 PolarHBondContact OD1-OG1 2.75Å; E349-T382 CarbonylContact C-O 3.54Å; E349-T382 VanDerWaalsContact CA-O 3.24Å; E349-T382 WeakPolarHBondContact CA-O 3.42Å; E349-T382 PolarHBondContact N-O 3.44Å; A350-T382 PolarHBondContact N-O 2.93Å; T382-Y397 WeakPolarHBondContact CA-O 3.49Å; T382-I398 HydrophobicContact CG2-CG1 4.37Å
383H98.6Very high97Very high7 Ų735.2 Ų35.23%0.03219%0.192CC..EExtended strand (participates in β ladder)trans-114.3127179.9-64.6165.3000110.1F219 T231 E349 T385 S396 Y397 H399F219-H383 AromaticContact CD1-CE1 3.76Å; F219-H383 AromaticContact CD1-ND1 3.62Å; F219-H383 AromaticContact CE1-CE1 3.95Å; F219-H383 AromaticContact CE1-ND1 3.48Å; F219-H383 WeakPolarHBondContact CE1-ND1 3.24Å; T231-H383 PolarHBondContact OG1-O 2.88Å; E349-H383 VanDerWaalsContact CB-CD2 3.46Å; E349-H383 WeakPolarHBondContact CB-CD2 3.45Å; E349-H383 PolarHBondContact O-CD2 3.09Å; E349-H383 IonicContact OE2-CD2 2.81Å; E349-H383 IonicContact OE2-CE1 3.66Å; E349-H383 IonicContact OE2-NE2 3.62Å; E349-H383 PolarHBondContact OE2-NE2 3.19Å; H383-T385 VanDerWaalsContact C-N 3.3Å; H383-T385 PolarHBondContact O-N 3.2Å; H383-T385 VanDerWaalsContact O-N 3.11Å; H383-S396 CarbonylContact O-C 3.55Å; H383-S396 WeakPolarHBondContact O-CA 3.46Å; H383-S396 PolarHBondContact O-OG 3.49Å; H383-Y397 PolarHBondContact N-O 3.21Å; H383-Y397 PolarHBondContact O-N 3.26Å; H383-H399 AromaticContact CE1-CD2 3.54Å; H383-H399 AromaticContact CE1-NE2 3.88Å; H383-H399 AromaticContact CG-CD2 3.94Å; H383-H399 AromaticContact ND1-CD2 3.29Å; H383-H399 PolarHBondContact ND1-CD2 3.13Å; H383-H399 VanDerWaalsContact ND1-CD2 3.29Å; H383-H399 AromaticContact ND1-NE2 3.24Å; H383-H399 PolarHBondContact ND1-NE2 3.05Å
384S98.3Very high97.3Very high6 Ų634 Ų344%0.04218%0.182CC..  trans-8186.3163.5-63.10000107.7T231 A350 H386 K387T231-S384 VanDerWaalsContact CB-OG 3.23Å; T231-S384 WeakPolarHBondContact CB-OG 3.33Å; T231-S384 WeakPolarHBondContact OG1-CA 3.3Å; T231-S384 WeakPolarHBondContact OG1-CB 3.32Å; T231-S384 PolarHBondContact OG1-N 2.94Å; T231-S384 PolarHBondContact OG1-OG 2.71Å; A350-S384 WeakPolarHBondContact CB-OG 3.37Å; A350-S384 VanDerWaalsContact O-CB 3.3Å; A350-S384 WeakPolarHBondContact O-CB 3.46Å; A350-S384 PolarHBondContact O-N 3.32Å; S384-H386 PolarHBondContact O-N 3.31Å; S384-K387 VanDerWaalsContact CB-CD 3.46Å; S384-K387 VanDerWaalsContact CB-CG 3.5Å; S384-K387 WeakPolarHBondContact O-CB 3.17Å; S384-K387 PolarHBondContact O-N 3.42Å; S384-K387 WeakPolarHBondContact OG-CE 3.39Å
385T98Very high97.4Very high1 Ų131.9 Ų31.91%0.00617%0.172CC..Hα-helixtrans-50-39-179.2-37.20000111.3H383 K387 L389 A391 A395 S396 N432 A435H383-T385 VanDerWaalsContact C-N 3.3Å; H383-T385 PolarHBondContact O-N 3.2Å; H383-T385 VanDerWaalsContact O-N 3.11Å; T385-K387 VanDerWaalsContact C-N 3.26Å; T385-K387 PolarHBondContact O-N 3.26Å; T385-L389 HydrophobicContact CG2-CB 3.89Å; T385-L389 HydrophobicContact CG2-CD1 4.01Å; T385-L389 CarbonylContact O-C 3.58Å; T385-L389 VanDerWaalsContact O-CA 3.25Å; T385-L389 WeakPolarHBondContact O-CA 3.35Å; T385-L389 VanDerWaalsContact O-CB 3.24Å; T385-L389 WeakPolarHBondContact O-CB 3.2Å; T385-L389 PolarHBondContact O-N 3.28Å; T385-L389 VanDerWaalsContact O-N 3.1Å; T385-L389 VanDerWaalsContact O-O 3.04Å; T385-A391 HydrophobicContact CG2-CB 3.49Å; T385-A391 VanDerWaalsContact CG2-CB 3.49Å; T385-A395 PolarHBondContact N-O 3.34Å; T385-S396 WeakPolarHBondContact OG1-CA 3.26Å; T385-N432 VanDerWaalsContact CB-OD1 3.27Å; T385-N432 WeakPolarHBondContact CB-OD1 3.41Å; T385-N432 WeakPolarHBondContact CG2-OD1 3.37Å; T385-N432 PolarHBondContact OG1-OD1 2.97Å; T385-A435 HydrophobicContact CG2-CB 3.53Å
386H97.4Very high97.7Very high59 Ų5924.9 Ų24.927%0.27314%0.135SC..Hα-helixtrans-70.9-8-179.671.2-86.3000116.2S384 A391 L392 A395S384-H386 PolarHBondContact O-N 3.31Å; H386-A391 WeakPolarHBondContact CA-O 3.48Å; H386-L392 WeakPolarHBondContact CB-O 3.3Å; H386-A395 HydrophobicContact CB-CB 4.49Å; H386-A395 PolarHBondContact N-O 3.26Å; H386-A395 PolarHBondContact ND1-O 2.79Å
387K95.3Very high97.9Very high61 Ų6124.9 Ų24.927%0.26513%0.134SC..Hα-helixtrans-87.5-58.5-177.8-72.5-175-174179.20112.2W351 S384 T385W351-K387 HydrophobicContact CD2-CD 3.77Å; W351-K387 HydrophobicContact CE3-CB 3.87Å; W351-K387 HydrophobicContact CE3-CD 3.68Å; W351-K387 HydrophobicContact CE3-CG 4.28Å; W351-K387 HydrophobicContact CH2-CD 3.78Å; W351-K387 HydrophobicContact CH2-CG 4.29Å; W351-K387 HydrophobicContact CZ2-CD 3.84Å; W351-K387 HydrophobicContact CZ3-CB 3.78Å; W351-K387 HydrophobicContact CZ3-CD 3.68Å; W351-K387 HydrophobicContact CZ3-CG 4Å; S384-K387 VanDerWaalsContact CB-CD 3.46Å; S384-K387 VanDerWaalsContact CB-CG 3.5Å; S384-K387 WeakPolarHBondContact O-CB 3.17Å; S384-K387 PolarHBondContact O-N 3.42Å; S384-K387 WeakPolarHBondContact OG-CE 3.39Å; T385-K387 VanDerWaalsContact C-N 3.26Å; T385-K387 PolarHBondContact O-N 3.26Å
388L96Very high97.9Very high7 Ų724.9 Ų24.94%0.03713%0.134CC..Hα-helixtrans-128.71.9-174.3-70.5171000113.7W351 Y354 M585W351-L388 HydrophobicContact CB-CD1 4.39Å; W351-L388 HydrophobicContact CE3-CD1 3.7Å; W351-L388 HydrophobicContact CE3-CG 4.07Å; W351-L388 HydrophobicContact CZ3-CD1 4.44Å; W351-L388 HydrophobicContact CZ3-CG 4.45Å; W351-L388 VanDerWaalsContact O-CD1 3.26Å; W351-L388 WeakPolarHBondContact O-CD1 3.48Å; Y354-L388 HydrophobicContact CD1-CB 3.73Å; Y354-L388 HydrophobicContact CE1-CB 3.56Å; Y354-L388 HydrophobicContact CE1-CD1 3.56Å; Y354-L388 HydrophobicContact CE1-CG 4.14Å; L388-M585 WeakPolarHBondContact O-CE 3.09Å
389L97.1Very high97.9Very high9 Ų924.8 Ų24.85%0.04713%0.134CC..SBendtrans-102.8-178.4157.8-54.9178.2000109.7F219 T385 M439 M585F219-L389 HydrophobicContact CE1-CD1 4.12Å; F219-L389 HydrophobicContact CZ-CD1 3.74Å; T385-L389 HydrophobicContact CG2-CB 3.89Å; T385-L389 HydrophobicContact CG2-CD1 4.01Å; T385-L389 CarbonylContact O-C 3.58Å; T385-L389 VanDerWaalsContact O-CA 3.25Å; T385-L389 WeakPolarHBondContact O-CA 3.35Å; T385-L389 VanDerWaalsContact O-CB 3.24Å; T385-L389 WeakPolarHBondContact O-CB 3.2Å; T385-L389 PolarHBondContact O-N 3.28Å; T385-L389 VanDerWaalsContact O-N 3.1Å; T385-L389 VanDerWaalsContact O-O 3.04Å; L389-M439 HydrophobicContact CD2-CG 4.13Å; L389-M439 HydrophobicContact CD2-SD 3.83Å; L389-M585 VanDerWaalsContact CA-CE 3.48Å; L389-M585 HydrophobicContact CB-CE 4.17Å; L389-M585 HydrophobicContact CD2-CE 3.42Å; L389-M585 VanDerWaalsContact CD2-CE 3.42Å; L389-M585 HydrophobicContact CG-CE 4.37Å
390N96.1Very high97.9Very high57 Ų5725.1 Ų25.131%0.30514%0.136SC..SBendtrans-102.576.1-175.7-65.4-34.3000111.4M438N390-M438 HydrophobicContact CB-CE 4.19Å; N390-M438 HydrophobicContact CB-SD 3.79Å; N390-M438 WeakPolarHBondContact ND2-CE 3.22Å
391A97.9Very high97.9Very high20 Ų2025.4 Ų25.417%0.16514%0.137CC..  trans-135.7161.4176.200000112.3T385 H386 A395 A435T385-A391 HydrophobicContact CG2-CB 3.49Å; T385-A391 VanDerWaalsContact CG2-CB 3.49Å; H386-A391 WeakPolarHBondContact CA-O 3.48Å; A391-A395 HydrophobicContact CB-CB 3.62Å; A391-A435 HydrophobicContact CB-CB 4.15Å
392L97.8Very high97.8Very high90 Ų9028.8 Ų28.847%0.47115%0.153SC..  trans-68.4150.7178.2-65.7176.6000111.1H386 A395 A427 S431H386-L392 WeakPolarHBondContact CB-O 3.3Å; L392-A395 WeakPolarHBondContact O-CB 3.47Å; L392-A395 PolarHBondContact O-N 3.02Å; L392-A427 HydrophobicContact CD1-CB 4.24Å; L392-S431 PolarHBondContact N-OG 3.08Å
393S97.7Very high97.7Very high91 Ų9130.1 Ų30.164%0.63617%0.166SC*.THydrogen-bonded Turntrans-45.2143.5173.3-61.20000112.1A395S393-A395 PolarHBondContact O-N 2.92Å
394Q97.7Very high97.6Very high110 Ų11034.7 Ų34.751%0.51418%0.183SC..THydrogen-bonded Turntrans75-10.2-172.3-46.4173.6-31.200115.5V228 V229 G230 S396 I428V228-Q394 CarbonylContact C-O 3.11Å; V229-Q394 PolarHBondContact N-O 2.84Å; G230-Q394 VanDerWaalsContact CA-O 3.23Å; G230-Q394 WeakPolarHBondContact CA-O 3.36Å; G230-Q394 PolarHBondContact N-O 3.31Å; Q394-S396 PolarHBondContact O-N 2.82Å; Q394-I428 HydrophobicContact CB-CD1 4.43Å
395A98.5Very high97.5Very high0 Ų036 Ų360%020%0.197CC..  trans-67.6131.8172.500000111.2T385 H386 A391 L392 S393 I428 N432T385-A395 PolarHBondContact N-O 3.34Å; H386-A395 HydrophobicContact CB-CB 4.49Å; H386-A395 PolarHBondContact N-O 3.26Å; H386-A395 PolarHBondContact ND1-O 2.79Å; A391-A395 HydrophobicContact CB-CB 3.62Å; L392-A395 WeakPolarHBondContact O-CB 3.47Å; L392-A395 PolarHBondContact O-N 3.02Å; S393-A395 PolarHBondContact O-N 2.92Å; A395-I428 HydrophobicContact CB-CG2 3.84Å; A395-N432 WeakPolarHBondContact CB-OD1 3.18Å
396S98.7Very high97.4Very high0 Ų038.2 Ų38.20%022%0.215CC..EExtended strand (participates in β ladder)trans-151.7158.4-178.6-177.90000110.1V227 T231 S234 H383 T385 Q394 N432V227-S396 PolarHBondContact N-O 3.44Å; V227-S396 PolarHBondContact O-N 3.07Å; T231-S396 WeakPolarHBondContact CA-OG 3.47Å; T231-S396 PolarHBondContact N-OG 3.18Å; T231-S396 PolarHBondContact OG1-OG 3.09Å; S234-S396 PolarHBondContact OG-OG 2.8Å; H383-S396 CarbonylContact O-C 3.55Å; H383-S396 WeakPolarHBondContact O-CA 3.46Å; H383-S396 PolarHBondContact O-OG 3.49Å; T385-S396 WeakPolarHBondContact OG1-CA 3.26Å; Q394-S396 PolarHBondContact O-N 2.82Å; S396-N432 PolarHBondContact O-ND2 3.13Å
397Y98.6Very high97.4Very high1 Ų136.3 Ų36.30%0.00421%0.207CC..EExtended strand (participates in β ladder)trans-124.8146.8168.8-85.2-75.8000111.1A215 W225 T382 H383 H399 N432 V436A215-Y397 HydrophobicContact CB-CD1 4.35Å; A215-Y397 HydrophobicContact CB-CE1 3.73Å; W225-Y397 WeakPolarHBondContact O-CA 3.37Å; W225-Y397 VanDerWaalsContact O-CD1 3.3Å; W225-Y397 WeakPolarHBondContact O-CD1 3.35Å; T382-Y397 WeakPolarHBondContact CA-O 3.49Å; H383-Y397 PolarHBondContact N-O 3.21Å; H383-Y397 PolarHBondContact O-N 3.26Å; Y397-H399 WeakPolarHBondContact CB-NE2 3.42Å; Y397-H399 AromaticContact CG-CE1 3.89Å; Y397-N432 HydrophobicContact CE2-CB 3.63Å; Y397-N432 WeakPolarHBondContact CE2-OD1 3.47Å; Y397-N432 PolarHBondContact OH-O 3.36Å; Y397-V436 HydrophobicContact CE2-CG2 3.66Å
398I98.8Very high97.4Very high0 Ų038.6 Ų38.60%022%0.222CC..EExtended strand (participates in β ladder)trans-106.1122.9159.4-57.3165.1000107S224 W225 V227 T237 I238 T382 V400 F412S224-I398 CarbonylContact C-O 3.55Å; S224-I398 WeakPolarHBondContact CA-O 3.48Å; W225-I398 HydrophobicContact CB-CB 4.27Å; W225-I398 HydrophobicContact CB-CD1 4.47Å; W225-I398 PolarHBondContact N-O 2.96Å; W225-I398 PolarHBondContact O-N 2.86Å; V227-I398 HydrophobicContact CG2-CD1 3.94Å; V227-I398 HydrophobicContact CG2-CG1 4.03Å; T237-I398 HydrophobicContact CG2-CD1 3.76Å; I238-I398 HydrophobicContact CD1-CG1 4.39Å; I238-I398 HydrophobicContact CD1-CG2 3.82Å; I238-I398 HydrophobicContact CG1-CD1 4.34Å; I238-I398 HydrophobicContact CG1-CG2 3.91Å; T382-I398 HydrophobicContact CG2-CG1 4.37Å; I398-V400 HydrophobicContact CG2-CG2 4.04Å; I398-F412 HydrophobicContact CD1-CE1 4.16Å; I398-F412 HydrophobicContact CD1-CZ 4.02Å; I398-F412 HydrophobicContact CG2-CZ 4.02Å
399H98.8Very high97.4Very high0 Ų041.5 Ų41.50%024%0.235CC..EExtended strand (participates in β ladder)trans-107.8137172.4-58.7-62.4000109.8F219 A221 S224 M367 F380 A381 H383 Y397F219-H399 AromaticContact CD1-CE1 3.84Å; F219-H399 AromaticContact CD1-NE2 3.48Å; F219-H399 WeakPolarHBondContact CD1-NE2 3.46Å; F219-H399 AromaticContact CD2-CE1 3.82Å; F219-H399 AromaticContact CE1-NE2 3.94Å; F219-H399 AromaticContact CG-CE1 3.45Å; F219-H399 VanDerWaalsContact CG-CE1 3.45Å; F219-H399 WeakPolarHBondContact CG-CE1 3.35Å; F219-H399 AromaticContact CG-NE2 3.61Å; A221-H399 HydrophobicContact CB-CB 3.88Å; S224-H399 PolarHBondContact OG-ND1 3.38Å; M367-H399 HydrophobicContact CE-CB 4.36Å; M367-H399 HydrophobicContact CG-CB 3.89Å; M367-H399 HydrophobicContact SD-CB 4.05Å; F380-H399 CarbonylContact C-O 3.15Å; F380-H399 WeakPolarHBondContact CA-O 3.45Å; A381-H399 HydrophobicContact CB-CB 4.3Å; A381-H399 PolarHBondContact N-O 3.45Å; A381-H399 PolarHBondContact O-N 2.85Å; H383-H399 AromaticContact CE1-CD2 3.54Å; H383-H399 AromaticContact CE1-NE2 3.88Å; H383-H399 AromaticContact CG-CD2 3.94Å; H383-H399 AromaticContact ND1-CD2 3.29Å; H383-H399 PolarHBondContact ND1-CD2 3.13Å; H383-H399 VanDerWaalsContact ND1-CD2 3.29Å; H383-H399 AromaticContact ND1-NE2 3.24Å; H383-H399 PolarHBondContact ND1-NE2 3.05Å; Y397-H399 WeakPolarHBondContact CB-NE2 3.42Å; Y397-H399 AromaticContact CG-CE1 3.89Å
400V98.5Very high97.4Very high8 Ų844.7 Ų44.75%0.04826%0.258CS..EExtended strand (participates in β ladder)trans-127.3124.5-178.5-173.40000109.7D222 R223 W225 T378 V379 F380 I398 E402D222-V400 PolarHBondContact N-O 3.3Å; R223-V400 PolarHBondContact N-O 3.01Å; R223-V400 PolarHBondContact O-N 2.95Å; W225-V400 HydrophobicContact CE3-CG2 4.07Å; W225-V400 HydrophobicContact CH2-CG2 4.5Å; W225-V400 HydrophobicContact CZ3-CB 4.17Å; W225-V400 HydrophobicContact CZ3-CG2 3.51Å; T378-V400 HydrophobicContact CG2-CG1 4Å; V379-V400 WeakPolarHBondContact O-CA 3.42Å; F380-V400 HydrophobicContact CD1-CB 4.44Å; F380-V400 HydrophobicContact CD1-CG1 4.22Å; F380-V400 HydrophobicContact CD1-CG2 3.61Å; F380-V400 HydrophobicContact CE1-CB 4.5Å; F380-V400 HydrophobicContact CE1-CG1 3.92Å; F380-V400 HydrophobicContact CE1-CG2 3.77Å; I398-V400 HydrophobicContact CG2-CG2 4.04Å; V400-E402 HydrophobicContact CG1-CG 4.46Å
401R97.8Very high97.3Very high6 Ų648 Ų482%0.02327%0.266CS..EExtended strand (participates in β ladder)trans-97.1114.5162.3177.872.982.8-127.1-1.2108G220 D222 M367 R368 G369 H374 T378 V379G220-R401 PolarHBondContact O-NH1 3.04Å; G220-R401 PolarHBondContact O-NH2 3.12Å; D222-R401 VanDerWaalsContact OD2-CA 3.3Å; D222-R401 WeakPolarHBondContact OD2-CA 3.46Å; D222-R401 VanDerWaalsContact OD2-CD 3.27Å; D222-R401 WeakPolarHBondContact OD2-CD 3.48Å; D222-R401 IonicContact OD2-NH1 3.82Å; M367-R401 HydrophobicContact CE-CB 4.1Å; M367-R401 HydrophobicContact SD-CB 4.05Å; R368-R401 PolarHBondContact O-NH2 3.47Å; G369-R401 PolarHBondContact O-NH2 3.29Å; H374-R401 HydrophobicContact CB-CG 3.9Å; H374-R401 WeakPolarHBondContact CD2-CG 3.33Å; H374-R401 VanDerWaalsContact CG-CG 3.41Å; T378-R401 WeakPolarHBondContact CA-O 3.4Å; V379-R401 HydrophobicContact CB-CB 4.21Å; V379-R401 PolarHBondContact N-O 3.24Å; V379-R401 PolarHBondContact O-N 3.48Å
402E97.1Very high97.3Very high72 Ų7247.2 Ų47.234%0.33626%0.259SS..  trans-75.1136.8-178.5-68.2-173.1-175.700110.6D222 R223 H374 V400 A406D222-E402 HydrophobicContact CB-CB 4.35Å; D222-E402 HydrophobicContact CB-CG 3.99Å; D222-E402 PolarHBondContact OD2-N 3.48Å; R223-E402 WeakPolarHBondContact CD-OE1 3.24Å; R223-E402 IonicContact CZ-OE1 2.66Å; R223-E402 IonicContact NE-OE1 2.76Å; R223-E402 PolarHBondContact NE-OE1 3.12Å; R223-E402 IonicContact NH2-OE1 3.91Å; H374-E402 PolarHBondContact CD2-O 3.08Å; H374-E402 VanDerWaalsContact CD2-O 3.28Å; V400-E402 HydrophobicContact CG1-CG 4.46Å; E402-A406 HydrophobicContact CB-CB 4.47Å
403G97.1Very high97.3Very high27 Ų2743.8 Ų43.828%0.27824%0.241SC..  trans-159.3-147177.800000111.7G376 T378 G405 A406G376-G403 WeakPolarHBondContact O-CA 3.35Å; T378-G403 PolarHBondContact OG1-N 2.96Å; G403-G405 PolarHBondContact O-N 3.14Å; G403-A406 WeakPolarHBondContact O-CB 3.2Å; G403-A406 PolarHBondContact O-N 2.8Å
404R97.1Very high97.3Very high104 Ų10445.1 Ų45.139%0.39224%0.237SC..BIsolated β-bridgetrans-56.7141.8169.3-59.5-172.7-57.9-87.35109.3E339 D343 N375 G376 T378 A406E339-R404 IonicContact OE2-CZ 3.15Å; E339-R404 IonicContact OE2-NH1 2.67Å; E339-R404 IonicContact OE2-NH2 2.72Å; E339-R404 PolarHBondContact OE2-NH2 3.4Å; D343-R404 HydrophobicContact CB-CB 4.17Å; D343-R404 IonicContact OD1-NE 2.72Å; D343-R404 PolarHBondContact OD1-NE 3.13Å; N375-R404 PolarHBondContact O-NH1 3.13Å; G376-R404 PolarHBondContact O-N 3.47Å; T378-R404 PolarHBondContact N-O 3.42Å; T378-R404 PolarHBondContact OG1-O 3.11Å; R404-A406 VanDerWaalsContact C-N 3.28Å; R404-A406 PolarHBondContact O-N 3.31Å
405G95.6Very high97.3Very high33 Ų3340.2 Ų40.234%0.3422%0.215SC..THydrogen-bonded Turntrans73.911.7178.700000115.8R344 G403R344-G405 PolarHBondContact NE-O 3.2Å; R344-G405 PolarHBondContact NH2-O 3.04Å; G403-G405 PolarHBondContact O-N 3.14Å
406A96.8Very high97.3Very high47 Ų4740.3 Ų40.339%0.38822%0.216SC..PPolyproline II helixtrans-52.4142.4-178.500000112.7T378 E402 G403 R404T378-A406 WeakPolarHBondContact OG1-CA 3.47Å; T378-A406 PolarHBondContact OG1-N 3.23Å; E402-A406 HydrophobicContact CB-CB 4.47Å; G403-A406 WeakPolarHBondContact O-CB 3.2Å; G403-A406 PolarHBondContact O-N 2.8Å; R404-A406 VanDerWaalsContact C-N 3.28Å; R404-A406 PolarHBondContact O-N 3.31Å
407I96.7Very high97.2Very high19 Ų1943.3 Ų43.310%0.09723%0.231CC..PPolyproline II helixtrans-99.5122.4-179.3-58.9178.1000107.9A241 C242 F380 F409 R411 F412A241-I407 HydrophobicContact CB-CD1 4.07Å; C242-I407 HydrophobicContact CB-CD1 4.36Å; C242-I407 WeakPolarHBondContact SG-CD1 3.45Å; F380-I407 HydrophobicContact CZ-CD1 3.99Å; I407-F409 PolarHBondContact O-N 3.41Å; I407-R411 HydrophobicContact CG2-CB 4Å; I407-R411 HydrophobicContact CG2-CG 3.83Å; I407-F412 HydrophobicContact CG2-CB 4Å; I407-F412 HydrophobicContact CG2-CD2 4.42Å
408N95.3Very high97.2Very high110 Ų11049.6 Ų49.659%0.58826%0.261SS*.PPolyproline II helixtrans-57.4140.2175.5175.8-83.4000110.9S410 R411 F412N408-S410 VanDerWaalsContact C-N 3.29Å; N408-S410 PolarHBondContact O-N 2.94Å; N408-S410 VanDerWaalsContact O-N 3.17Å; N408-S410 WeakPolarHBondContact OD1-CB 3.45Å; N408-S410 PolarHBondContact OD1-N 2.83Å; N408-R411 PolarHBondContact O-N 3.29Å; N408-F412 PolarHBondContact O-N 2.78Å; N408-F412 VanDerWaalsContact O-N 3.09Å
409F96.1Very high97.1Very high67 Ų6750.8 Ų50.829%0.29427%0.267SS..Hα-helixtrans-46.4-47.1-178.9-180-92.7000113.8H204 W225 I407 R411 F412 N413H204-F409 HydrophobicContact CB-CZ 4.06Å; H204-F409 AromaticContact CD2-CZ 3.44Å; H204-F409 VanDerWaalsContact CD2-CZ 3.44Å; H204-F409 WeakPolarHBondContact CD2-CZ 3.28Å; H204-F409 AromaticContact CG-CZ 3.79Å; W225-F409 HydrophobicContact CH2-CD2 4.45Å; W225-F409 AromaticContact CZ2-CD2 3.71Å; W225-F409 HydrophobicContact CZ2-CD2 3.71Å; W225-F409 AromaticContact CZ2-CE2 3.86Å; W225-F409 HydrophobicContact CZ2-CE2 3.86Å; I407-F409 PolarHBondContact O-N 3.41Å; F409-R411 VanDerWaalsContact C-N 3.31Å; F409-R411 PolarHBondContact O-N 3.25Å; F409-F412 PolarHBondContact O-N 3.25Å; F409-N413 HydrophobicContact CE1-CB 4.28Å; F409-N413 VanDerWaalsContact O-CB 3.31Å; F409-N413 WeakPolarHBondContact O-CB 3.27Å; F409-N413 PolarHBondContact O-N 3.02Å
410S95.9Very high96.9Very high76 Ų7651.7 Ų51.753%0.53127%0.274SS..Hα-helixtrans-63.1-37.5-177.8-59.30000112.3N408 Q414N408-S410 VanDerWaalsContact C-N 3.29Å; N408-S410 PolarHBondContact O-N 2.94Å; N408-S410 VanDerWaalsContact O-N 3.17Å; N408-S410 WeakPolarHBondContact OD1-CB 3.45Å; N408-S410 PolarHBondContact OD1-N 2.83Å; S410-Q414 WeakPolarHBondContact O-CG 3.15Å; S410-Q414 PolarHBondContact O-N 3.4Å
411R95.6Very high96.7Very high128 Ų12854 Ų5448%0.48329%0.288SS..Hα-helixtrans-68.7-46176172.6176.9163.1170.35.6111.1A241 I407 N408 F409 N413 Q414A241-R411 VanDerWaalsContact O-CZ 3.24Å; A241-R411 PolarHBondContact O-NE 2.92Å; A241-R411 PolarHBondContact O-NH2 2.92Å; I407-R411 HydrophobicContact CG2-CB 4Å; I407-R411 HydrophobicContact CG2-CG 3.83Å; N408-R411 PolarHBondContact O-N 3.29Å; F409-R411 VanDerWaalsContact C-N 3.31Å; F409-R411 PolarHBondContact O-N 3.25Å; R411-N413 VanDerWaalsContact C-N 3.32Å; R411-N413 PolarHBondContact O-N 3.02Å; R411-Q414 PolarHBondContact O-N 3.03Å
412F98Very high96.5Very high3 Ų358.9 Ų58.91%0.01332%0.319CS..Hα-helixtrans-63.3-41.7178.6-165.4-85.1000111.1W225 T237 I238 A241 F380 I398 I407 N408 F409 Q414 A415 Y416W225-F412 AromaticContact CD2-CD1 3.97Å; W225-F412 HydrophobicContact CD2-CD1 3.97Å; W225-F412 AromaticContact CD2-CE1 3.75Å; W225-F412 HydrophobicContact CD2-CE1 3.75Å; W225-F412 AromaticContact CE2-CD1 3.57Å; W225-F412 AromaticContact CE2-CE1 3.87Å; W225-F412 HydrophobicContact CE3-CD1 4.28Å; W225-F412 AromaticContact CE3-CE1 3.92Å; W225-F412 HydrophobicContact CE3-CE1 3.92Å; W225-F412 HydrophobicContact CG-CE1 4.22Å; W225-F412 AromaticContact CH2-CD1 3.85Å; W225-F412 HydrophobicContact CH2-CD1 3.85Å; W225-F412 HydrophobicContact CH2-CE1 4.28Å; W225-F412 HydrophobicContact CH2-CG 4.25Å; W225-F412 HydrophobicContact CZ2-CB 4.37Å; W225-F412 AromaticContact CZ2-CD1 3.52Å; W225-F412 HydrophobicContact CZ2-CD1 3.52Å; W225-F412 HydrophobicContact CZ2-CE1 4.14Å; W225-F412 HydrophobicContact CZ2-CG 4.16Å; W225-F412 HydrophobicContact CZ3-CD1 4.23Å; W225-F412 HydrophobicContact CZ3-CE1 4.19Å; T237-F412 HydrophobicContact CG2-CE1 3.83Å; T237-F412 HydrophobicContact CG2-CZ 3.91Å; I238-F412 HydrophobicContact CG1-CE2 4.26Å; I238-F412 HydrophobicContact CG1-CZ 4.06Å; A241-F412 HydrophobicContact CB-CD2 3.53Å; A241-F412 HydrophobicContact CB-CE2 3.87Å; A241-F412 HydrophobicContact CB-CG 4.26Å; F380-F412 HydrophobicContact CD1-CE2 4.27Å; F380-F412 HydrophobicContact CE1-CD2 4.28Å; F380-F412 AromaticContact CE1-CE2 3.68Å; F380-F412 HydrophobicContact CE1-CE2 3.68Å; I398-F412 HydrophobicContact CD1-CE1 4.16Å; I398-F412 HydrophobicContact CD1-CZ 4.02Å; I398-F412 HydrophobicContact CG2-CZ 4.02Å; I407-F412 HydrophobicContact CG2-CB 4Å; I407-F412 HydrophobicContact CG2-CD2 4.42Å; N408-F412 PolarHBondContact O-N 2.78Å; N408-F412 VanDerWaalsContact O-N 3.09Å; F409-F412 PolarHBondContact O-N 3.25Å; F412-Q414 VanDerWaalsContact C-N 3.3Å; F412-Q414 PolarHBondContact O-N 2.89Å; F412-A415 PolarHBondContact O-N 3.29Å; F412-A415 VanDerWaalsContact O-N 3.12Å; F412-Y416 PolarHBondContact O-N 2.89Å
413N97.8Very high96.3Very high17 Ų1759.8 Ų59.89%0.09133%0.334CS..Hα-helixtrans-64.8-31.9-179.1-163.327.9000112.7L202 H204 F409 R411 A415 Y416 M417L202-N413 PolarHBondContact O-ND2 3.05Å; H204-N413 PolarHBondContact NE2-OD1 2.81Å; F409-N413 HydrophobicContact CE1-CB 4.28Å; F409-N413 VanDerWaalsContact O-CB 3.31Å; F409-N413 WeakPolarHBondContact O-CB 3.27Å; F409-N413 PolarHBondContact O-N 3.02Å; R411-N413 VanDerWaalsContact C-N 3.32Å; R411-N413 PolarHBondContact O-N 3.02Å; N413-A415 VanDerWaalsContact C-N 3.35Å; N413-A415 PolarHBondContact O-N 3.09Å; N413-Y416 PolarHBondContact O-N 3Å; N413-Y416 VanDerWaalsContact OD1-CD1 3.29Å; N413-Y416 WeakPolarHBondContact OD1-CD1 3.21Å; N413-M417 WeakPolarHBondContact O-CB 3.25Å; N413-M417 VanDerWaalsContact O-CG 3.29Å; N413-M417 WeakPolarHBondContact O-CG 3.26Å; N413-M417 PolarHBondContact O-N 3.22Å
414Q97.4Very high96.1Very high120 Ų12058.8 Ų58.856%0.56132%0.322SS*.Hα-helixtrans-60.2-44.2172.7-69.5-58.3-40.300112S410 R411 F412 M417 M418S410-Q414 WeakPolarHBondContact O-CG 3.15Å; S410-Q414 PolarHBondContact O-N 3.4Å; R411-Q414 PolarHBondContact O-N 3.03Å; F412-Q414 VanDerWaalsContact C-N 3.3Å; F412-Q414 PolarHBondContact O-N 2.89Å; Q414-M417 VanDerWaalsContact CD-CE 3.48Å; Q414-M417 HydrophobicContact CG-CE 4.49Å; Q414-M417 PolarHBondContact O-N 3.06Å; Q414-M418 WeakPolarHBondContact O-CG 3.36Å; Q414-M418 PolarHBondContact O-N 3.08Å
415A97.6Very high96Very high6 Ų657 Ų575%0.0532%0.32CS..Hα-helixtrans-66-39.1175.700000111.7T237 Q240 A241 F412 N413 M418 H419T237-A415 HydrophobicContact CG2-CB 4.39Å; T237-A415 WeakPolarHBondContact O-CB 3.36Å; Q240-A415 HydrophobicContact CB-CB 4.01Å; A241-A415 HydrophobicContact CB-CB 3.94Å; F412-A415 PolarHBondContact O-N 3.29Å; F412-A415 VanDerWaalsContact O-N 3.12Å; N413-A415 VanDerWaalsContact C-N 3.35Å; N413-A415 PolarHBondContact O-N 3.09Å; A415-M418 PolarHBondContact O-N 3.37Å; A415-H419 PolarHBondContact O-CD2 3.44Å
416Y98.1Very high95.9Very high3 Ų355.4 Ų55.41%0.01230%0.304CS..Hα-helixtrans-60.2-48175.9173.1-97.5000111.9L201 L202 H204 W225 S226 V227 T237 F412 N413 M418 H419 A420L201-Y416 WeakPolarHBondContact CD1-OH 3Å; L201-Y416 WeakPolarHBondContact CG-OH 3.43Å; L202-Y416 HydrophobicContact CD2-CE1 4.21Å; H204-Y416 AromaticContact CE1-CE1 3.72Å; H204-Y416 AromaticContact NE2-CD1 3.84Å; H204-Y416 AromaticContact NE2-CE1 3.84Å; W225-Y416 HydrophobicContact CB-CD2 4.27Å; W225-Y416 HydrophobicContact CB-CE2 4.16Å; W225-Y416 AromaticContact CD1-CD2 3.76Å; W225-Y416 AromaticContact CD1-CG 3.9Å; W225-Y416 HydrophobicContact CG-CD2 4.3Å; S226-Y416 WeakPolarHBondContact O-CE2 3.41Å; S226-Y416 PolarHBondContact O-OH 3.27Å; V227-Y416 HydrophobicContact CG2-CD2 4.43Å; V227-Y416 HydrophobicContact CG2-CE2 3.96Å; T237-Y416 HydrophobicContact CG2-CD2 4.47Å; F412-Y416 PolarHBondContact O-N 2.89Å; N413-Y416 PolarHBondContact O-N 3Å; N413-Y416 VanDerWaalsContact OD1-CD1 3.29Å; N413-Y416 WeakPolarHBondContact OD1-CD1 3.21Å; Y416-M418 VanDerWaalsContact C-N 3.26Å; Y416-M418 PolarHBondContact O-N 2.91Å; Y416-H419 PolarHBondContact O-N 3.07Å; Y416-H419 VanDerWaalsContact O-N 3.1Å; Y416-A420 HydrophobicContact CD1-CB 4.48Å; Y416-A420 HydrophobicContact CE1-CB 4.12Å; Y416-A420 WeakPolarHBondContact O-CB 3.34Å; Y416-A420 PolarHBondContact O-N 3.45Å
417M97.3Very high95.8Very high63 Ų6353.9 Ų53.931%0.3129%0.291SS..Hα-helixtrans-63.8-27.4178.9-69.3-170.8-64.600113.5L202 N413 Q414 H419L202-M417 HydrophobicContact CD2-CB 4.36Å; L202-M417 HydrophobicContact CD2-CG 3.9Å; N413-M417 WeakPolarHBondContact O-CB 3.25Å; N413-M417 VanDerWaalsContact O-CG 3.29Å; N413-M417 WeakPolarHBondContact O-CG 3.26Å; N413-M417 PolarHBondContact O-N 3.22Å; Q414-M417 VanDerWaalsContact CD-CE 3.48Å; Q414-M417 HydrophobicContact CG-CE 4.49Å; Q414-M417 PolarHBondContact O-N 3.06Å; M417-H419 PolarHBondContact O-N 3.33Å
418M96.9Very high95.8Very high132 Ų13253.5 Ų53.565%0.6529%0.289SS*.Hα-helixtrans-67.9-23.6175.2-73.6176.362.400113.3Q414 A415 Y416Q414-M418 WeakPolarHBondContact O-CG 3.36Å; Q414-M418 PolarHBondContact O-N 3.08Å; A415-M418 PolarHBondContact O-N 3.37Å; Y416-M418 VanDerWaalsContact C-N 3.26Å; Y416-M418 PolarHBondContact O-N 2.91Å
419H96.9Very high95.9Very high26 Ų2648.3 Ų48.312%0.1226%0.261CS..Hα-helixtrans-107.8-22.6-178.5-70.8-59.6000113.8R236 T237 Q240 A415 Y416 M417R236-H419 WeakPolarHBondContact CB-NE2 3.42Å; T237-H419 PolarHBondContact OG1-CD2 3.11Å; Q240-H419 VanDerWaalsContact CD-NE2 3.28Å; Q240-H419 PolarHBondContact OE1-NE2 3.43Å; Q240-H419 VanDerWaalsContact OE1-NE2 3.12Å; A415-H419 PolarHBondContact O-CD2 3.44Å; Y416-H419 PolarHBondContact O-N 3.07Å; Y416-H419 VanDerWaalsContact O-N 3.1Å; M417-H419 PolarHBondContact O-N 3.33Å
420A95.6Very high95.9Very high18 Ų1845.5 Ų45.515%0.14925%0.251CS..SBendtrans-76.1150.9175.900000111.6L202 Y416L202-A420 HydrophobicContact CD2-CB 3.57Å; Y416-A420 HydrophobicContact CD1-CB 4.48Å; Y416-A420 HydrophobicContact CE1-CB 4.12Å; Y416-A420 WeakPolarHBondContact O-CB 3.34Å; Y416-A420 PolarHBondContact O-N 3.45Å
421T94.3Very high96Very high57 Ų5742.7 Ų42.735%0.3523%0.231SC..  trans-82.2145.1168.9171.50000110.3V228 S423 P424V228-T421 HydrophobicContact CG2-CG2 4.07Å; T421-S423 PolarHBondContact O-N 3.42Å; T421-S423 PolarHBondContact OG1-N 2.71Å; T421-S423 VanDerWaalsContact OG1-N 3.08Å; T421-S423 PolarHBondContact OG1-O 2.8Å; T421-P424 VanDerWaalsContact CG2-CA 3.49Å; T421-P424 HydrophobicContact CG2-CB 3.99Å
422T93Very high96.1Very high108 Ų10836.6 Ų36.666%0.66321%0.208SC*.SBendtrans-74.1-4.9171.157.20000113.5L202L202-T422 HydrophobicContact CD1-CG2 4.11Å
423S93.4Very high96Very high92 Ų9236.4 Ų36.464%0.64321%0.207SC*.SBendtrans-135.872.7174.8-59.80000109T421T421-S423 PolarHBondContact O-N 3.42Å; T421-S423 PolarHBondContact OG1-N 2.71Å; T421-S423 VanDerWaalsContact OG1-N 3.08Å; T421-S423 PolarHBondContact OG1-O 2.8Å
424P93.5Very high96Very high6 Ų637.7 Ų37.74%0.03922%0.215CC..  trans-68.6141.9179.130.5-34.7000110.2L201 V228 T421 Y426L201-P424 HydrophobicContact CB-CG 4.2Å; L201-P424 HydrophobicContact CD2-CB 3.64Å; L201-P424 HydrophobicContact CD2-CG 3.72Å; V228-P424 HydrophobicContact CG2-CB 3.85Å; T421-P424 VanDerWaalsContact CG2-CA 3.49Å; T421-P424 HydrophobicContact CG2-CB 3.99Å; P424-Y426 HydrophobicContact CG-CD1 4.19Å; P424-Y426 HydrophobicContact CG-CE1 3.92Å; P424-Y426 VanDerWaalsContact O-CD1 3.25Å; P424-Y426 WeakPolarHBondContact O-CD1 3.39Å; P424-Y426 PolarHBondContact O-N 2.91Å; P424-Y426 VanDerWaalsContact O-N 3.13Å
425L93.4Very high96Very high65 Ų6532.1 Ų32.134%0.3419%0.189SC..  trans-71.9108.2172.1178.659.2000108.8D190 A427 I428 C429D190-L425 HydrophobicContact CB-CD1 4.16Å; L425-A427 HydrophobicContact CD1-CB 4.38Å; L425-A427 HydrophobicContact CG-CB 4.12Å; L425-A427 PolarHBondContact O-N 3.23Å; L425-A427 VanDerWaalsContact O-N 3.11Å; L425-I428 HydrophobicContact CB-CD1 4.07Å; L425-I428 HydrophobicContact CB-CG1 4.17Å; L425-I428 HydrophobicContact CD2-CD1 4.11Å; L425-I428 HydrophobicContact CD2-CG1 4Å; L425-I428 HydrophobicContact CG-CD1 4.48Å; L425-I428 HydrophobicContact CG-CG1 4.2Å; L425-I428 WeakPolarHBondContact O-CB 3.34Å; L425-I428 PolarHBondContact O-N 3.46Å; L425-C429 PolarHBondContact O-N 3.47Å
426Y94.1Very high96Very high1 Ų131.9 Ų31.90%0.00419%0.187CC..Hα-helixtrans-60.8-24.7-174.3-7814.8000113.2L147 M191 L198 F208 P424 I428 C429 A430L147-Y426 HydrophobicContact CD2-CD2 3.6Å; L147-Y426 HydrophobicContact CD2-CE2 4.42Å; L147-Y426 HydrophobicContact CD2-CG 4.37Å; M191-Y426 HydrophobicContact CB-CD2 4.28Å; M191-Y426 HydrophobicContact CB-CE2 4.34Å; M191-Y426 HydrophobicContact CE-CD2 4.03Å; M191-Y426 HydrophobicContact CE-CE2 4.49Å; L198-Y426 HydrophobicContact CD1-CD2 4.19Å; L198-Y426 HydrophobicContact CD1-CE2 3.77Å; F208-Y426 HydrophobicContact CE2-CE1 4.09Å; F208-Y426 HydrophobicContact CE2-CE2 4.04Å; F208-Y426 AromaticContact CE2-CZ 3.73Å; F208-Y426 AromaticContact CZ-CD1 3.79Å; F208-Y426 HydrophobicContact CZ-CD1 3.79Å; F208-Y426 HydrophobicContact CZ-CD2 4.23Å; F208-Y426 AromaticContact CZ-CE1 3.56Å; F208-Y426 HydrophobicContact CZ-CE1 3.56Å; F208-Y426 AromaticContact CZ-CE2 3.99Å; F208-Y426 HydrophobicContact CZ-CE2 3.99Å; F208-Y426 HydrophobicContact CZ-CG 4.12Å; F208-Y426 AromaticContact CZ-CZ 3.65Å; P424-Y426 HydrophobicContact CG-CD1 4.19Å; P424-Y426 HydrophobicContact CG-CE1 3.92Å; P424-Y426 VanDerWaalsContact O-CD1 3.25Å; P424-Y426 WeakPolarHBondContact O-CD1 3.39Å; P424-Y426 PolarHBondContact O-N 2.91Å; P424-Y426 VanDerWaalsContact O-N 3.13Å; Y426-I428 VanDerWaalsContact C-N 3.31Å; Y426-I428 PolarHBondContact O-N 3.34Å; Y426-C429 WeakPolarHBondContact O-CB 3.29Å; Y426-C429 PolarHBondContact O-N 2.87Å; Y426-A430 WeakPolarHBondContact O-CB 3.44Å; Y426-A430 PolarHBondContact O-N 3.23Å
427A94.7Very high95.9Very high15 Ų1533.1 Ų33.112%0.12420%0.196CC..Hα-helixtrans-61-38.1172.400000112.6L186 L392 L425 S431L186-A427 HydrophobicContact CD1-CB 3.95Å; L392-A427 HydrophobicContact CD1-CB 4.24Å; L425-A427 HydrophobicContact CD1-CB 4.38Å; L425-A427 HydrophobicContact CG-CB 4.12Å; L425-A427 PolarHBondContact O-N 3.23Å; L425-A427 VanDerWaalsContact O-N 3.11Å; A427-S431 PolarHBondContact O-N 3.45Å
428I96.8Very high95.8Very high11 Ų1133 Ų336%0.05620%0.196CC..Hα-helixtrans-67.3-46.3175.4-57.3177.4000109.3V228 Q394 A395 L425 Y426 A430 S431 N432V228-I428 HydrophobicContact CB-CB 4.46Å; V228-I428 HydrophobicContact CB-CG2 4.05Å; V228-I428 HydrophobicContact CG1-CB 4.12Å; V228-I428 HydrophobicContact CG1-CG2 3.83Å; Q394-I428 HydrophobicContact CB-CD1 4.43Å; A395-I428 HydrophobicContact CB-CG2 3.84Å; L425-I428 HydrophobicContact CB-CD1 4.07Å; L425-I428 HydrophobicContact CB-CG1 4.17Å; L425-I428 HydrophobicContact CD2-CD1 4.11Å; L425-I428 HydrophobicContact CD2-CG1 4Å; L425-I428 HydrophobicContact CG-CD1 4.48Å; L425-I428 HydrophobicContact CG-CG1 4.2Å; L425-I428 WeakPolarHBondContact O-CB 3.34Å; L425-I428 PolarHBondContact O-N 3.46Å; Y426-I428 VanDerWaalsContact C-N 3.31Å; Y426-I428 PolarHBondContact O-N 3.34Å; I428-A430 VanDerWaalsContact C-N 3.32Å; I428-A430 PolarHBondContact O-N 3.08Å; I428-S431 PolarHBondContact O-N 3.44Å; I428-S431 VanDerWaalsContact O-N 3.15Å; I428-S431 PolarHBondContact O-OG 3Å; I428-N432 PolarHBondContact O-N 2.85Å; I428-N432 VanDerWaalsContact O-N 3.08Å
429C96.6Very high95.8Very high1 Ų126.9 Ų26.91%0.00717%0.166CC..Hα-helixtrans-57.4-45.5176.8-54.70000112L143 F208 V228 L425 Y426 S431 N432 D433L143-C429 HydrophobicContact CD2-CB 3.62Å; F208-C429 HydrophobicContact CE1-CB 3.77Å; V228-C429 WeakPolarHBondContact CG1-SG 3.29Å; L425-C429 PolarHBondContact O-N 3.47Å; Y426-C429 WeakPolarHBondContact O-CB 3.29Å; Y426-C429 PolarHBondContact O-N 2.87Å; C429-S431 VanDerWaalsContact C-N 3.33Å; C429-S431 PolarHBondContact O-N 3.24Å; C429-N432 VanDerWaalsContact O-CB 3.31Å; C429-N432 WeakPolarHBondContact O-CB 3.11Å; C429-N432 PolarHBondContact O-N 3.24Å; C429-D433 PolarHBondContact O-N 3.36Å; C429-D433 VanDerWaalsContact O-N 3.08Å
430A96.3Very high95.7Very high8 Ų828 Ų287%0.06617%0.172CC..Hα-helixtrans-62.9-39.1177.200000112.1F144 L147 Y426 I428 N432 D433 V434F144-A430 HydrophobicContact CD2-CB 3.95Å; L147-A430 HydrophobicContact CD1-CB 3.66Å; Y426-A430 WeakPolarHBondContact O-CB 3.44Å; Y426-A430 PolarHBondContact O-N 3.23Å; I428-A430 VanDerWaalsContact C-N 3.32Å; I428-A430 PolarHBondContact O-N 3.08Å; A430-N432 VanDerWaalsContact C-N 3.29Å; A430-N432 PolarHBondContact O-N 2.95Å; A430-D433 PolarHBondContact O-N 3.26Å; A430-V434 WeakPolarHBondContact O-CG2 3.47Å; A430-V434 PolarHBondContact O-N 3.48Å
431S97.8Very high95.5Very high16 Ų1629.2 Ų29.211%0.11219%0.187CC..Hα-helixtrans-64.9-34.3176.577.50000112.6L392 A427 I428 C429 A435L392-S431 PolarHBondContact N-OG 3.08Å; A427-S431 PolarHBondContact O-N 3.45Å; I428-S431 PolarHBondContact O-N 3.44Å; I428-S431 VanDerWaalsContact O-N 3.15Å; I428-S431 PolarHBondContact O-OG 3Å; C429-S431 VanDerWaalsContact C-N 3.33Å; C429-S431 PolarHBondContact O-N 3.24Å; S431-A435 VanDerWaalsContact O-CB 3.28Å; S431-A435 WeakPolarHBondContact O-CB 3.4Å; S431-A435 PolarHBondContact O-N 2.99Å
432N97.9Very high95.4Very high0 Ų030.1 Ų30.10%019%0.19CC..Hα-helixtrans-63.2-48.3171.4-111.3-2.3000110.8S226 T385 A395 S396 Y397 I428 C429 A430 V434 A435 V436S226-N432 PolarHBondContact OG-ND2 2.91Å; T385-N432 VanDerWaalsContact CB-OD1 3.27Å; T385-N432 WeakPolarHBondContact CB-OD1 3.41Å; T385-N432 WeakPolarHBondContact CG2-OD1 3.37Å; T385-N432 PolarHBondContact OG1-OD1 2.97Å; A395-N432 WeakPolarHBondContact CB-OD1 3.18Å; S396-N432 PolarHBondContact O-ND2 3.13Å; Y397-N432 HydrophobicContact CE2-CB 3.63Å; Y397-N432 WeakPolarHBondContact CE2-OD1 3.47Å; Y397-N432 PolarHBondContact OH-O 3.36Å; I428-N432 PolarHBondContact O-N 2.85Å; I428-N432 VanDerWaalsContact O-N 3.08Å; C429-N432 VanDerWaalsContact O-CB 3.31Å; C429-N432 WeakPolarHBondContact O-CB 3.11Å; C429-N432 PolarHBondContact O-N 3.24Å; A430-N432 VanDerWaalsContact C-N 3.29Å; A430-N432 PolarHBondContact O-N 2.95Å; N432-V434 PolarHBondContact O-N 3.37Å; N432-A435 PolarHBondContact O-N 3.03Å; N432-V436 WeakPolarHBondContact O-CG2 3.42Å; N432-V436 PolarHBondContact O-N 2.71Å; N432-V436 VanDerWaalsContact O-N 3.08Å
433D97.8Very high95.4Very high0 Ų026 Ų260%017%0.166CC..Hα-helixtrans-61.5-42.2178.7-166.943.2000112.2P141 L143 F144 S211 C429 A430 V436 S437P141-D433 VanDerWaalsContact C-OD2 3.31Å; P141-D433 VanDerWaalsContact CB-CG 3.47Å; P141-D433 VanDerWaalsContact CB-OD2 3.25Å; P141-D433 WeakPolarHBondContact CB-OD2 3.38Å; P141-D433 HydrophobicContact CG-CB 4.32Å; P141-D433 VanDerWaalsContact CG-OD2 3.27Å; P141-D433 WeakPolarHBondContact CG-OD2 3.4Å; L143-D433 WeakPolarHBondContact CA-OD2 3.36Å; L143-D433 HydrophobicContact CB-CB 4.17Å; L143-D433 VanDerWaalsContact CB-OD2 3.26Å; L143-D433 WeakPolarHBondContact CB-OD2 3.44Å; L143-D433 PolarHBondContact N-OD2 3.2Å; F144-D433 PolarHBondContact N-OD2 2.88Å; S211-D433 WeakPolarHBondContact CB-OD1 3.49Å; C429-D433 PolarHBondContact O-N 3.36Å; C429-D433 VanDerWaalsContact O-N 3.08Å; A430-D433 PolarHBondContact O-N 3.26Å; D433-V436 PolarHBondContact O-N 3.48Å; D433-S437 PolarHBondContact O-N 2.99Å; D433-S437 VanDerWaalsContact O-N 3.13Å
434V97.2Very high95.5Very high44 Ų4421.7 Ų21.727%0.26714%0.136SC..Hα-helixtrans-66.9-41.7174.4172.80000111.5P141 F144 A430 N432 V436 S437 M438P141-V434 HydrophobicContact CG-CG2 4.19Å; F144-V434 HydrophobicContact CB-CG2 4.01Å; F144-V434 HydrophobicContact CD1-CG2 3.83Å; F144-V434 HydrophobicContact CE1-CG2 4.47Å; F144-V434 HydrophobicContact CG-CG2 3.89Å; A430-V434 WeakPolarHBondContact O-CG2 3.47Å; A430-V434 PolarHBondContact O-N 3.48Å; N432-V434 PolarHBondContact O-N 3.37Å; V434-V436 VanDerWaalsContact C-N 3.27Å; V434-V436 PolarHBondContact O-N 3.15Å; V434-S437 WeakPolarHBondContact O-CB 3.21Å; V434-S437 PolarHBondContact O-N 3.39Å; V434-M438 HydrophobicContact CG1-CG 4.29Å; V434-M438 HydrophobicContact CG1-SD 4.24Å; V434-M438 WeakPolarHBondContact O-CG 3.29Å; V434-M438 PolarHBondContact O-N 2.83Å
435A97.8Very high95.6Very high2 Ų224.9 Ų24.92%0.01715%0.152CC..Hα-helixtrans-59.6-38.4177.100000112.2T385 A391 S431 N432 M439T385-A435 HydrophobicContact CG2-CB 3.53Å; A391-A435 HydrophobicContact CB-CB 4.15Å; S431-A435 VanDerWaalsContact O-CB 3.28Å; S431-A435 WeakPolarHBondContact O-CB 3.4Å; S431-A435 PolarHBondContact O-N 2.99Å; N432-A435 PolarHBondContact O-N 3.03Å; A435-M439 WeakPolarHBondContact O-CG 3.47Å; A435-M439 PolarHBondContact O-N 3.22Å
436V97.7Very high95.6Very high1 Ų122.6 Ų22.61%0.00614%0.141CC..Hα-helixtrans-61.8-48.2172.1175.20000110.4Y214 A215 V218 F219 Y397 N432 D433 V434 M438 M439 D440Y214-V436 HydrophobicContact CD1-CB 4.26Å; Y214-V436 HydrophobicContact CD1-CG1 3.52Å; Y214-V436 HydrophobicContact CE1-CB 4.17Å; Y214-V436 HydrophobicContact CE1-CG1 3.51Å; Y214-V436 HydrophobicContact CG-CG1 4.4Å; A215-V436 HydrophobicContact CB-CG1 4.25Å; A215-V436 HydrophobicContact CB-CG2 3.72Å; V218-V436 HydrophobicContact CB-CG1 3.76Å; V218-V436 HydrophobicContact CG1-CG1 4.06Å; V218-V436 HydrophobicContact CG2-CG1 3.75Å; F219-V436 HydrophobicContact CD2-CG2 4.43Å; F219-V436 HydrophobicContact CE2-CB 4.34Å; F219-V436 HydrophobicContact CE2-CG1 4.35Å; F219-V436 HydrophobicContact CE2-CG2 3.83Å; Y397-V436 HydrophobicContact CE2-CG2 3.66Å; N432-V436 WeakPolarHBondContact O-CG2 3.42Å; N432-V436 PolarHBondContact O-N 2.71Å; N432-V436 VanDerWaalsContact O-N 3.08Å; D433-V436 PolarHBondContact O-N 3.48Å; V434-V436 VanDerWaalsContact C-N 3.27Å; V434-V436 PolarHBondContact O-N 3.15Å; V436-M438 VanDerWaalsContact C-N 3.31Å; V436-M438 PolarHBondContact O-N 3.17Å; V436-M439 PolarHBondContact O-N 3.45Å; V436-D440 PolarHBondContact O-N 3.44Å
437S95.5Very high95.6Very high29 Ų2923.3 Ų23.320%0.20315%0.145CC..Hα-helixtrans-60.4-39.2-179.3-177.70000113Y214 D433 V434 M439 D440Y214-S437 WeakPolarHBondContact OH-CA 3.27Å; D433-S437 PolarHBondContact O-N 2.99Å; D433-S437 VanDerWaalsContact O-N 3.13Å; V434-S437 WeakPolarHBondContact O-CB 3.21Å; V434-S437 PolarHBondContact O-N 3.39Å; S437-M439 PolarHBondContact O-N 2.93Å; S437-D440 PolarHBondContact O-N 2.94Å
438M95.3Very high95.7Very high62 Ų6222.9 Ų22.931%0.30514%0.141SC..Hα-helixtrans-62.6-27.6176-67.8179.176.300112.8N390 V434 V436 S443 L447N390-M438 HydrophobicContact CB-CE 4.19Å; N390-M438 HydrophobicContact CB-SD 3.79Å; N390-M438 WeakPolarHBondContact ND2-CE 3.22Å; V434-M438 HydrophobicContact CG1-CG 4.29Å; V434-M438 HydrophobicContact CG1-SD 4.24Å; V434-M438 WeakPolarHBondContact O-CG 3.29Å; V434-M438 PolarHBondContact O-N 2.83Å; V436-M438 VanDerWaalsContact C-N 3.31Å; V436-M438 PolarHBondContact O-N 3.17Å; M438-S443 VanDerWaalsContact O-CB 3.25Å; M438-S443 WeakPolarHBondContact O-CB 3.38Å; M438-S443 PolarHBondContact O-OG 3.46Å; M438-L447 HydrophobicContact CB-CD1 4.22Å; M438-L447 HydrophobicContact CE-CD1 4.37Å; M438-L447 WeakPolarHBondContact O-CD1 3.33Å
439M96.2Very high95.7Very high3 Ų323.7 Ų23.72%0.01514%0.144CC..Hα-helixtrans-92-9.2-179-64.7-63.4102.100113.7V218 F357 L389 A435 V436 S437 G444 L447 M585V218-M439 HydrophobicContact CG1-CB 4.33Å; F357-M439 HydrophobicContact CD1-CB 4.02Å; F357-M439 WeakPolarHBondContact CD1-O 3.45Å; F357-M439 HydrophobicContact CD2-CB 3.95Å; F357-M439 HydrophobicContact CD2-CG 3.89Å; F357-M439 HydrophobicContact CD2-SD 3.57Å; F357-M439 VanDerWaalsContact CD2-SD 3.57Å; F357-M439 HydrophobicContact CE1-CB 3.71Å; F357-M439 HydrophobicContact CE2-CB 3.64Å; F357-M439 HydrophobicContact CE2-CG 3.59Å; F357-M439 HydrophobicContact CE2-SD 3.9Å; F357-M439 HydrophobicContact CG-CB 4.16Å; F357-M439 HydrophobicContact CG-SD 4.16Å; F357-M439 HydrophobicContact CZ-CB 3.52Å; F357-M439 HydrophobicContact CZ-CG 3.98Å; L389-M439 HydrophobicContact CD2-CG 4.13Å; L389-M439 HydrophobicContact CD2-SD 3.83Å; A435-M439 WeakPolarHBondContact O-CG 3.47Å; A435-M439 PolarHBondContact O-N 3.22Å; V436-M439 PolarHBondContact O-N 3.45Å; S437-M439 PolarHBondContact O-N 2.93Å; M439-G444 WeakPolarHBondContact O-CA 3.13Å; M439-L447 HydrophobicContact CE-CB 4.08Å; M439-L447 HydrophobicContact CE-CD1 3.37Å; M439-L447 HydrophobicContact CE-CG 4.37Å; M439-M585 HydrophobicContact CE-CE 3.72Å; M439-M585 HydrophobicContact CE-SD 3.38Å; M439-M585 WeakPolarHBondContact CE-SD 3.4Å; M439-M585 HydrophobicContact SD-CE 4.19Å; M439-M585 HydrophobicContact SD-SD 4.26Å
440D94.9Very high95.5Very high48 Ų4825.2 Ų25.226%0.25715%0.151SC..SBendtrans-72142.2-177.5-165.413.4000111.8Y214 R217 V218 V436 S437Y214-D440 WeakPolarHBondContact CE2-OD2 3.31Å; Y214-D440 WeakPolarHBondContact OH-CB 3.41Å; Y214-D440 PolarHBondContact OH-OD2 3.31Å; R217-D440 IonicContact CZ-OD1 3.34Å; R217-D440 IonicContact CZ-OD2 2.55Å; R217-D440 IonicContact NH1-OD1 3.85Å; R217-D440 IonicContact NH1-OD2 3.59Å; R217-D440 VanDerWaalsContact NH2-CG 3.3Å; R217-D440 IonicContact NH2-OD1 3.77Å; R217-D440 PolarHBondContact NH2-OD1 3.11Å; R217-D440 IonicContact NH2-OD2 3.14Å; R217-D440 PolarHBondContact NH2-OD2 2.96Å; V218-D440 HydrophobicContact CG1-CB 4.39Å; V218-D440 HydrophobicContact CG2-CB 3.9Å; V436-D440 PolarHBondContact O-N 3.44Å; S437-D440 PolarHBondContact O-N 2.94Å
441G91.5Very high95.5Very high45 Ų4525.3 Ų25.346%0.46415%0.152SC..THydrogen-bonded Turntrans58-142.3179.900000114.3S443G441-S443 PolarHBondContact O-N 2.95Å
442N92.1Very high95.4Very high76 Ų7624.6 Ų24.641%0.40615%0.146SC..Hα-helixtrans-66-23.6-176.5-67.5-16.1000113.5H81 E82 G444 L445 S446H81-N442 PolarHBondContact O-ND2 3.02Å; E82-N442 CarbonylContact O-C 3.48Å; E82-N442 VanDerWaalsContact O-C 3.23Å; N442-G444 VanDerWaalsContact C-N 3.34Å; N442-G444 PolarHBondContact O-N 2.97Å; N442-L445 PolarHBondContact O-N 3.04Å; N442-S446 PolarHBondContact O-N 3.33Å
443S93Very high95.3Very high22 Ų2227 Ų2715%0.15416%0.159CC..Hα-helixtrans-62.8-40.9-177.7179.30000111.6E82 M438 G441 L445 S446 L447E82-S443 WeakPolarHBondContact O-CA 3.38Å; E82-S443 PolarHBondContact O-N 3.5Å; M438-S443 VanDerWaalsContact O-CB 3.25Å; M438-S443 WeakPolarHBondContact O-CB 3.38Å; M438-S443 PolarHBondContact O-OG 3.46Å; G441-S443 PolarHBondContact O-N 2.95Å; S443-L445 VanDerWaalsContact C-N 3.33Å; S443-L445 PolarHBondContact O-N 3.23Å; S443-S446 PolarHBondContact O-N 3.1Å; S443-L447 WeakPolarHBondContact O-CB 3.26Å; S443-L447 VanDerWaalsContact O-CG 3.26Å; S443-L447 WeakPolarHBondContact O-CG 3.4Å; S443-L447 PolarHBondContact O-N 3.46Å
444G95.3Very high95.2Very high1 Ų128 Ų281%0.0116%0.164CC..Hα-helixtrans-59.5-42.7175.400000112.6M439 N442 T448M439-G444 WeakPolarHBondContact O-CA 3.13Å; N442-G444 VanDerWaalsContact C-N 3.34Å; N442-G444 PolarHBondContact O-N 2.97Å; G444-T448 WeakPolarHBondContact O-CB 3.43Å; G444-T448 VanDerWaalsContact O-CG2 3.31Å; G444-T448 WeakPolarHBondContact O-CG2 3.15Å; G444-T448 PolarHBondContact O-N 2.94Å; G444-T448 VanDerWaalsContact O-N 3.09Å; G444-T448 PolarHBondContact O-OG1 2.86Å
445L95.6Very high95.2Very high73 Ų7326 Ų2638%0.38215%0.151SC..Hα-helixtrans-65.8-47.3175.4179.460.5000111.5F357 P359 N442 S443 L447 T448 Q449F357-L445 VanDerWaalsContact O-CA 3.29Å; F357-L445 WeakPolarHBondContact O-CA 3.44Å; P359-L445 HydrophobicContact CG-CD1 4.47Å; N442-L445 PolarHBondContact O-N 3.04Å; S443-L445 VanDerWaalsContact C-N 3.33Å; S443-L445 PolarHBondContact O-N 3.23Å; L445-L447 PolarHBondContact O-N 3.46Å; L445-T448 PolarHBondContact O-N 3.24Å; L445-T448 PolarHBondContact O-OG1 3.01Å; L445-T448 VanDerWaalsContact O-OG1 3.1Å; L445-Q449 WeakPolarHBondContact O-CB 3.47Å; L445-Q449 PolarHBondContact O-N 3.3Å
446S93.7Very high95.2Very high16 Ų1625.9 Ų25.911%0.11215%0.151CC..Hα-helixtrans-60.5-45.5-179.9-177.10000112.2E82 R83 N442 S443 E450E82-S446 WeakPolarHBondContact O-CB 3.18Å; R83-S446 WeakPolarHBondContact CG-OG 2.98Å; R83-S446 PolarHBondContact NE-OG 3.35Å; N442-S446 PolarHBondContact O-N 3.33Å; S443-S446 PolarHBondContact O-N 3.1Å; S446-E450 PolarHBondContact O-N 3.06Å
447L94.6Very high95.1Very high16 Ų1628.4 Ų28.48%0.08416%0.164CC..Hα-helixtrans-68.2-42.8-178.5-71.6170.3000112.1M438 M439 S443 L445 V451 M585M438-L447 HydrophobicContact CB-CD1 4.22Å; M438-L447 HydrophobicContact CE-CD1 4.37Å; M438-L447 WeakPolarHBondContact O-CD1 3.33Å; M439-L447 HydrophobicContact CE-CB 4.08Å; M439-L447 HydrophobicContact CE-CD1 3.37Å; M439-L447 HydrophobicContact CE-CG 4.37Å; S443-L447 WeakPolarHBondContact O-CB 3.26Å; S443-L447 VanDerWaalsContact O-CG 3.26Å; S443-L447 WeakPolarHBondContact O-CG 3.4Å; S443-L447 PolarHBondContact O-N 3.46Å; L445-L447 PolarHBondContact O-N 3.46Å; L447-V451 WeakPolarHBondContact O-CG2 3.35Å; L447-V451 PolarHBondContact O-N 3.33Å; L447-M585 HydrophobicContact CB-CG 4.49Å; L447-M585 HydrophobicContact CB-SD 3.7Å; L447-M585 HydrophobicContact CD1-SD 4.31Å; L447-M585 HydrophobicContact CG-SD 4.49Å
448T96.5Very high95.2Very high6 Ų627 Ų274%0.03716%0.155CC..Hα-helixtrans-69.4-38.8176.653.70000112.1F357 N358 G444 L445 V451 I452F357-T448 HydrophobicContact CB-CG2 4.13Å; N358-T448 WeakPolarHBondContact CB-OG1 3.47Å; N358-T448 PolarHBondContact ND2-OG1 3.14Å; G444-T448 WeakPolarHBondContact O-CB 3.43Å; G444-T448 VanDerWaalsContact O-CG2 3.31Å; G444-T448 WeakPolarHBondContact O-CG2 3.15Å; G444-T448 PolarHBondContact O-N 2.94Å; G444-T448 VanDerWaalsContact O-N 3.09Å; G444-T448 PolarHBondContact O-OG1 2.86Å; L445-T448 PolarHBondContact O-N 3.24Å; L445-T448 PolarHBondContact O-OG1 3.01Å; L445-T448 VanDerWaalsContact O-OG1 3.1Å; T448-V451 PolarHBondContact O-N 3.42Å; T448-I452 WeakPolarHBondContact O-CD1 3.24Å; T448-I452 WeakPolarHBondContact O-CG1 3.29Å; T448-I452 PolarHBondContact O-N 3.04Å
449Q95.6Very high95.3Very high28 Ų2824.1 Ų24.113%0.13114%0.14CC..Hα-helixtrans-62.3-43.7177.3-170.864.252.900111.6N358 L445 V451 I452 D453 T505N358-Q449 PolarHBondContact ND2-OE1 2.6Å; L445-Q449 WeakPolarHBondContact O-CB 3.47Å; L445-Q449 PolarHBondContact O-N 3.3Å; Q449-V451 VanDerWaalsContact C-N 3.3Å; Q449-V451 PolarHBondContact O-N 3.04Å; Q449-I452 PolarHBondContact O-N 2.97Å; Q449-D453 PolarHBondContact NE2-OD1 3.14Å; Q449-D453 WeakPolarHBondContact O-CB 3.29Å; Q449-D453 PolarHBondContact O-N 2.79Å; Q449-T505 VanDerWaalsContact NE2-CB 3.33Å; Q449-T505 PolarHBondContact NE2-O 2.99Å; Q449-T505 PolarHBondContact NE2-OG1 2.91Å
450E93.6Very high95.4Very high33 Ų3324 Ų2415%0.15414%0.14CC..Hα-helixtrans-57.5-42.9177175167.195.100112.1R83 S446 D453 E454 R589R83-E450 IonicContact CZ-OE1 2.97Å; R83-E450 IonicContact CZ-OE2 3.67Å; R83-E450 IonicContact NH1-OE1 3.66Å; R83-E450 IonicContact NH2-OE1 3.26Å; R83-E450 PolarHBondContact NH2-OE1 2.95Å; R83-E450 IonicContact NH2-OE2 3.9Å; R83-E450 PolarHBondContact NH2-OE2 2.9Å; S446-E450 PolarHBondContact O-N 3.06Å; E450-D453 PolarHBondContact O-N 2.86Å; E450-E454 WeakPolarHBondContact O-CG 3.4Å; E450-E454 PolarHBondContact O-N 2.69Å; E450-R589 IonicContact OE2-CZ 3.01Å; E450-R589 VanDerWaalsContact OE2-CZ 3.26Å; E450-R589 IonicContact OE2-NE 3.78Å; E450-R589 PolarHBondContact OE2-NE 3.36Å; E450-R589 IonicContact OE2-NH2 2.77Å; E450-R589 PolarHBondContact OE2-NH2 2.98Å
451V95.3Very high95.5Very high11 Ų1122.4 Ų22.47%0.06713%0.133CC..Hα-helixtrans-68.8-38.7179.2-178.20000111.5L447 T448 Q449 A455 I535 F583 M585L447-V451 WeakPolarHBondContact O-CG2 3.35Å; L447-V451 PolarHBondContact O-N 3.33Å; T448-V451 PolarHBondContact O-N 3.42Å; Q449-V451 VanDerWaalsContact C-N 3.3Å; Q449-V451 PolarHBondContact O-N 3.04Å; V451-A455 WeakPolarHBondContact O-CB 3.25Å; V451-A455 PolarHBondContact O-N 3Å; V451-I535 HydrophobicContact CG1-CB 4.02Å; V451-I535 HydrophobicContact CG1-CD1 4.28Å; V451-I535 HydrophobicContact CG1-CG2 3.81Å; V451-F583 HydrophobicContact CG1-CB 3.95Å; V451-F583 WeakPolarHBondContact CG1-O 3.31Å; V451-M585 HydrophobicContact CG2-CB 4.21Å; V451-M585 HydrophobicContact CG2-CG 3.7Å
452I97.1Very high95.8Very high0 Ų020.3 Ų20.30%011%0.111CC..Hα-helixtrans-63.5-45.7174.8-69.2160.4000110.1N358 I360 Y361 T448 Q449 E454 A455 V456 T505 P534 I535N358-I452 HydrophobicContact CB-CD1 4.25Å; N358-I452 WeakPolarHBondContact ND2-CD1 3.44Å; I360-I452 HydrophobicContact CG2-CD1 3.86Å; Y361-I452 HydrophobicContact CE2-CD1 4.14Å; T448-I452 WeakPolarHBondContact O-CD1 3.24Å; T448-I452 WeakPolarHBondContact O-CG1 3.29Å; T448-I452 PolarHBondContact O-N 3.04Å; Q449-I452 PolarHBondContact O-N 2.97Å; I452-E454 PolarHBondContact O-N 3.06Å; I452-A455 PolarHBondContact O-N 3.42Å; I452-V456 HydrophobicContact CG2-CG2 4.28Å; I452-V456 WeakPolarHBondContact O-CB 3.12Å; I452-V456 VanDerWaalsContact O-CG2 3.3Å; I452-V456 WeakPolarHBondContact O-CG2 3.46Å; I452-V456 PolarHBondContact O-N 3.18Å; I452-T505 HydrophobicContact CG2-CG2 4.06Å; I452-P534 HydrophobicContact CG2-CB 4.22Å; I452-P534 HydrophobicContact CG2-CG 4.49Å; I452-I535 HydrophobicContact CG1-CG2 3.74Å
453D95.4Very high96Very high52 Ų5217.2 Ų17.228%0.27810%0.097SC..Hα-helixtrans-58.5-49.2178.5-66.4-19000110.5Q449 E450 A455 V456 D457 T505Q449-D453 PolarHBondContact NE2-OD1 3.14Å; Q449-D453 WeakPolarHBondContact O-CB 3.29Å; Q449-D453 PolarHBondContact O-N 2.79Å; E450-D453 PolarHBondContact O-N 2.86Å; D453-A455 PolarHBondContact O-N 3.03Å; D453-V456 PolarHBondContact O-N 2.91Å; D453-D457 WeakPolarHBondContact O-CB 3.24Å; D453-D457 PolarHBondContact O-N 3.36Å; D453-T505 WeakPolarHBondContact OD1-CB 3.49Å; D453-T505 WeakPolarHBondContact OD1-CG2 3.11Å; D453-T505 PolarHBondContact OD1-OG1 2.82Å; D453-T505 VanDerWaalsContact OD1-OG1 3.07Å
454E95.6Very high96.3Very high21 Ų2121 Ų2110%0.09811%0.108CC..Hα-helixtrans-63-39.1177.5-71.6-70.9149.400113.4E450 I452 F458 F583 R589 G590 W592E450-E454 WeakPolarHBondContact O-CG 3.4Å; E450-E454 PolarHBondContact O-N 2.69Å; I452-E454 PolarHBondContact O-N 3.06Å; E454-F458 PolarHBondContact O-N 3.39Å; E454-F458 VanDerWaalsContact O-N 3.09Å; E454-F583 HydrophobicContact CB-CD1 4.37Å; E454-R589 VanDerWaalsContact OE1-CA 3.24Å; E454-R589 WeakPolarHBondContact OE1-CA 3.48Å; E454-R589 VanDerWaalsContact OE1-CB 3.25Å; E454-R589 WeakPolarHBondContact OE1-CB 3.46Å; E454-R589 VanDerWaalsContact OE1-CG 3.31Å; E454-R589 WeakPolarHBondContact OE1-CG 3.46Å; E454-G590 PolarHBondContact OE2-N 2.88Å; E454-W592 PolarHBondContact OE2-NE1 3.36Å; E454-W592 VanDerWaalsContact OE2-NE1 3.11Å
455A97Very high96.4Very high0 Ų022.7 Ų22.70%012%0.116CC..Hα-helixtrans-68.4-39.8177.800000111.9V451 I452 D453 R459 P534 I535 V537 F583V451-A455 WeakPolarHBondContact O-CB 3.25Å; V451-A455 PolarHBondContact O-N 3Å; I452-A455 PolarHBondContact O-N 3.42Å; D453-A455 PolarHBondContact O-N 3.03Å; A455-R459 VanDerWaalsContact O-CG 3.27Å; A455-R459 WeakPolarHBondContact O-CG 3.41Å; A455-R459 PolarHBondContact O-N 2.83Å; A455-P534 WeakPolarHBondContact CB-O 3.48Å; A455-I535 HydrophobicContact CB-CB 4.4Å; A455-I535 HydrophobicContact CB-CG2 4.45Å; A455-V537 HydrophobicContact CB-CG2 4.07Å; A455-F583 HydrophobicContact CB-CB 4Å; A455-F583 HydrophobicContact CB-CD1 3.96Å; A455-F583 HydrophobicContact CB-CD2 4.39Å; A455-F583 HydrophobicContact CB-CG 3.86Å
456V97.4Very high96.5Very high0 Ų022.8 Ų22.80%011%0.112CC..Hα-helixtrans-67.4-44.6175.9170.20000111I452 D453 F458 R459 Q460 T501 L504 T505 W511 P534I452-V456 HydrophobicContact CG2-CG2 4.28Å; I452-V456 WeakPolarHBondContact O-CB 3.12Å; I452-V456 VanDerWaalsContact O-CG2 3.3Å; I452-V456 WeakPolarHBondContact O-CG2 3.46Å; I452-V456 PolarHBondContact O-N 3.18Å; D453-V456 PolarHBondContact O-N 2.91Å; V456-F458 VanDerWaalsContact C-N 3.3Å; V456-F458 PolarHBondContact O-N 2.89Å; V456-R459 PolarHBondContact O-N 2.98Å; V456-R459 VanDerWaalsContact O-N 3.12Å; V456-Q460 HydrophobicContact CG1-CG 4.21Å; V456-Q460 WeakPolarHBondContact O-CG 3.45Å; V456-Q460 PolarHBondContact O-N 3.26Å; V456-T501 HydrophobicContact CG1-CG2 4.14Å; V456-L504 HydrophobicContact CG1-CB 3.71Å; V456-L504 HydrophobicContact CG1-CD1 3.65Å; V456-L504 HydrophobicContact CG1-CG 4.35Å; V456-L504 HydrophobicContact CG2-CB 4.37Å; V456-T505 HydrophobicContact CB-CG2 3.73Å; V456-T505 HydrophobicContact CG1-CG2 3.91Å; V456-T505 HydrophobicContact CG2-CG2 3.71Å; V456-W511 HydrophobicContact CG2-CH2 4.07Å; V456-W511 HydrophobicContact CG2-CZ2 3.61Å; V456-P534 HydrophobicContact CG2-CB 4.48Å
457D96.1Very high96.6Very high55 Ų5526.5 Ų26.529%0.29413%0.126SC..Hα-helixtrans-57.6-44.4176.7-78-12.8000111.3D453 Q460 A461 W592D453-D457 WeakPolarHBondContact O-CB 3.24Å; D453-D457 PolarHBondContact O-N 3.36Å; D457-Q460 PolarHBondContact O-N 2.83Å; D457-A461 WeakPolarHBondContact O-CB 3.42Å; D457-A461 PolarHBondContact O-N 2.79Å; D457-W592 HydrophobicContact CB-CZ2 4.18Å
458F97Very high96.8Very high0 Ų031.2 Ų31.20%015%0.148CC..Hα-helixtrans-61.7-46.8173.7173.3-109000112.4E454 V456 Q460 A461 M462 V537 I539 F583 W592 L595 V596E454-F458 PolarHBondContact O-N 3.39Å; E454-F458 VanDerWaalsContact O-N 3.09Å; V456-F458 VanDerWaalsContact C-N 3.3Å; V456-F458 PolarHBondContact O-N 2.89Å; F458-Q460 VanDerWaalsContact C-N 3.34Å; F458-Q460 PolarHBondContact O-N 2.85Å; F458-A461 PolarHBondContact O-N 2.78Å; F458-M462 HydrophobicContact CD1-CG 4.46Å; F458-M462 HydrophobicContact CD2-CG 4.14Å; F458-M462 HydrophobicContact CE1-CG 4.03Å; F458-M462 HydrophobicContact CE2-CG 3.69Å; F458-M462 HydrophobicContact CE2-SD 3.88Å; F458-M462 HydrophobicContact CZ-CG 3.62Å; F458-M462 HydrophobicContact CZ-SD 4.04Å; F458-M462 WeakPolarHBondContact O-CG 3.48Å; F458-M462 PolarHBondContact O-N 2.65Å; F458-V537 HydrophobicContact CD1-CB 4.36Å; F458-V537 HydrophobicContact CD1-CG1 3.73Å; F458-V537 HydrophobicContact CD1-CG2 4.42Å; F458-V537 HydrophobicContact CE1-CB 4.35Å; F458-V537 HydrophobicContact CE1-CG1 3.6Å; F458-I539 HydrophobicContact CE1-CG2 4.22Å; F458-I539 HydrophobicContact CZ-CG2 4.25Å; F458-F583 HydrophobicContact CB-CE1 3.98Å; F458-F583 HydrophobicContact CB-CZ 3.67Å; F458-F583 AromaticContact CD1-CE2 3.8Å; F458-F583 HydrophobicContact CD1-CE2 3.8Å; F458-F583 AromaticContact CD1-CZ 3.5Å; F458-F583 HydrophobicContact CD1-CZ 3.5Å; F458-F583 VanDerWaalsContact CD1-CZ 3.5Å; F458-F583 HydrophobicContact CD2-CZ 4.4Å; F458-F583 HydrophobicContact CE1-CE2 4.26Å; F458-F583 HydrophobicContact CE1-CZ 4.23Å; F458-F583 HydrophobicContact CG-CE1 4.38Å; F458-F583 HydrophobicContact CG-CE2 4.36Å; F458-F583 AromaticContact CG-CZ 3.59Å; F458-F583 HydrophobicContact CG-CZ 3.59Å; F458-W592 HydrophobicContact CB-CB 3.89Å; F458-W592 HydrophobicContact CB-CD2 4.15Å; F458-W592 HydrophobicContact CB-CE3 4.47Å; F458-W592 HydrophobicContact CB-CG 3.89Å; F458-W592 HydrophobicContact CD2-CB 3.68Å; F458-W592 HydrophobicContact CD2-CD2 4.38Å; F458-W592 HydrophobicContact CD2-CE3 4.09Å; F458-W592 HydrophobicContact CD2-CG 4.27Å; F458-W592 HydrophobicContact CG-CB 4.02Å; F458-W592 HydrophobicContact CG-CG 4.49Å; F458-L595 HydrophobicContact CE1-CD2 4.28Å; F458-L595 HydrophobicContact CE2-CD2 3.69Å; F458-L595 HydrophobicContact CE2-CG 3.96Å; F458-L595 HydrophobicContact CZ-CD2 3.51Å; F458-L595 HydrophobicContact CZ-CG 4.1Å; F458-V596 HydrophobicContact CD2-CG2 3.77Å; F458-V596 HydrophobicContact CE2-CG2 3.63Å
459R97.9Very high96.8Very high0 Ų033.6 Ų33.60%016%0.157CC..Hα-helixtrans-60.4-42.7177.9-73.2171.4179.4-82.47.3111.8A455 V456 M462 A463 W480 N481 F496 D533 P534 K536 V537A455-R459 VanDerWaalsContact O-CG 3.27Å; A455-R459 WeakPolarHBondContact O-CG 3.41Å; A455-R459 PolarHBondContact O-N 2.83Å; V456-R459 PolarHBondContact O-N 2.98Å; V456-R459 VanDerWaalsContact O-N 3.12Å; R459-M462 PolarHBondContact O-N 2.71Å; R459-A463 WeakPolarHBondContact O-CB 3.12Å; R459-A463 PolarHBondContact O-N 3.21Å; R459-W480 PolarHBondContact NH1-O 3.17Å; R459-N481 PolarHBondContact NH1-OD1 3.11Å; R459-F496 HydrophobicContact CB-CE1 3.71Å; R459-F496 HydrophobicContact CB-CZ 3.89Å; R459-D533 PolarHBondContact NH2-O 3.46Å; R459-P534 PolarHBondContact NE-O 3.23Å; R459-P534 PolarHBondContact NH2-O 3.19Å; R459-P534 VanDerWaalsContact NH2-O 3.11Å; R459-K536 PolarHBondContact NH2-O 2.82Å; R459-V537 HydrophobicContact CG-CG1 3.78Å; R459-V537 HydrophobicContact CG-CG2 4.26Å
460Q97.7Very high96.8Very high1 Ų135.4 Ų35.41%0.00517%0.171CC..Hα-helixtrans-65.5-42176.9-70.5-163.8-58.500111.4V456 D457 F458 M462 A463 R464 F496 A499 T501 L504V456-Q460 HydrophobicContact CG1-CG 4.21Å; V456-Q460 WeakPolarHBondContact O-CG 3.45Å; V456-Q460 PolarHBondContact O-N 3.26Å; D457-Q460 PolarHBondContact O-N 2.83Å; F458-Q460 VanDerWaalsContact C-N 3.34Å; F458-Q460 PolarHBondContact O-N 2.85Å; Q460-M462 PolarHBondContact O-N 3.33Å; Q460-A463 PolarHBondContact O-N 2.93Å; Q460-R464 WeakPolarHBondContact O-CG 3.46Å; Q460-R464 PolarHBondContact O-N 3.12Å; Q460-F496 HydrophobicContact CG-CD1 4.37Å; Q460-F496 HydrophobicContact CG-CE1 3.9Å; Q460-F496 PolarHBondContact NE2-O 2.74Å; Q460-A499 PolarHBondContact NE2-O 2.87Å; Q460-T501 PolarHBondContact OE1-OG1 3.13Å; Q460-T501 VanDerWaalsContact OE1-OG1 3.12Å; Q460-L504 HydrophobicContact CG-CD1 3.88Å
461A96.9Very high97Very high15 Ų1537.9 Ų37.912%0.12420%0.197CC..Hα-helixtrans-60-44.8174.800000111.7D457 F458 R464 L465 W592D457-A461 WeakPolarHBondContact O-CB 3.42Å; D457-A461 PolarHBondContact O-N 2.79Å; F458-A461 PolarHBondContact O-N 2.78Å; A461-R464 PolarHBondContact O-N 3.24Å; A461-L465 WeakPolarHBondContact O-CG 3.49Å; A461-L465 PolarHBondContact O-N 3.33Å; A461-W592 HydrophobicContact CB-CE3 4.46Å; A461-W592 HydrophobicContact CB-CH2 4.11Å; A461-W592 HydrophobicContact CB-CZ3 3.71Å
462M97.8Very high97Very high0 Ų044.1 Ų44.10%023%0.229CC..Hα-helixtrans-63.1-42.1175-69.2-55.5-58.600112.3F458 R459 Q460 L465 Y466 F476 F477 P479 I539 V596 L599F458-M462 HydrophobicContact CD1-CG 4.46Å; F458-M462 HydrophobicContact CD2-CG 4.14Å; F458-M462 HydrophobicContact CE1-CG 4.03Å; F458-M462 HydrophobicContact CE2-CG 3.69Å; F458-M462 HydrophobicContact CE2-SD 3.88Å; F458-M462 HydrophobicContact CZ-CG 3.62Å; F458-M462 HydrophobicContact CZ-SD 4.04Å; F458-M462 WeakPolarHBondContact O-CG 3.48Å; F458-M462 PolarHBondContact O-N 2.65Å; R459-M462 PolarHBondContact O-N 2.71Å; Q460-M462 PolarHBondContact O-N 3.33Å; M462-L465 PolarHBondContact O-N 3.43Å; M462-Y466 VanDerWaalsContact O-CB 3.3Å; M462-Y466 WeakPolarHBondContact O-CB 3.21Å; M462-Y466 PolarHBondContact O-N 3.25Å; M462-F476 HydrophobicContact CE-CD1 4.2Å; M462-F476 HydrophobicContact CE-CE1 3.53Å; M462-F476 HydrophobicContact CE-CZ 4.22Å; M462-F476 HydrophobicContact SD-CE1 4.24Å; M462-F477 HydrophobicContact CE-CB 3.66Å; M462-P479 HydrophobicContact CB-CB 4.21Å; M462-P479 HydrophobicContact CB-CG 4.2Å; M462-I539 HydrophobicContact CE-CG2 4.33Å; M462-I539 HydrophobicContact CG-CG2 4.44Å; M462-V596 HydrophobicContact SD-CG2 4.02Å; M462-L599 HydrophobicContact CE-CD1 3.89Å; M462-L599 HydrophobicContact SD-CD1 4Å
463A98Very high96.9Very high12 Ų1247.7 Ų47.710%0.09927%0.267CS..Hα-helixtrans-63.7-42.6177.500000112.2R459 Q460 Y466 K467 P479 F496 A497R459-A463 WeakPolarHBondContact O-CB 3.12Å; R459-A463 PolarHBondContact O-N 3.21Å; Q460-A463 PolarHBondContact O-N 2.93Å; A463-Y466 PolarHBondContact O-N 3.01Å; A463-K467 WeakPolarHBondContact O-CB 3.12Å; A463-K467 PolarHBondContact O-N 3.32Å; A463-P479 HydrophobicContact CB-CG 3.9Å; A463-F496 HydrophobicContact CB-CD1 4.12Å; A463-A497 HydrophobicContact CB-CB 3.8Å
464R97.7Very high97Very high102 Ų10247.1 Ų47.139%0.38527%0.267SS..Hα-helixtrans-61.4-50.7175.2-71.6177.3-167.1137.610.6111.4Q460 A461 Y466 K467 E468 A497Q460-R464 WeakPolarHBondContact O-CG 3.46Å; Q460-R464 PolarHBondContact O-N 3.12Å; A461-R464 PolarHBondContact O-N 3.24Å; R464-Y466 VanDerWaalsContact C-N 3.34Å; R464-Y466 PolarHBondContact O-N 3.14Å; R464-K467 WeakPolarHBondContact O-CB 3.22Å; R464-K467 PolarHBondContact O-N 2.79Å; R464-K467 VanDerWaalsContact O-N 3.17Å; R464-E468 WeakPolarHBondContact O-CG 3.3Å; R464-E468 PolarHBondContact O-N 3.45Å; R464-A497 HydrophobicContact CG-CB 3.78Å; R464-A497 VanDerWaalsContact CZ-O 3.28Å; R464-A497 PolarHBondContact NE-O 3.25Å; R464-A497 PolarHBondContact NH2-O 2.8Å
465L97.8Very high97.1Very high35 Ų3548.8 Ų48.818%0.18327%0.272CS..Hα-helixtrans-60.5-43.8177.9-71.3172.1000111.6A461 M462 K467 E468 F469 F476 V596A461-L465 WeakPolarHBondContact O-CG 3.49Å; A461-L465 PolarHBondContact O-N 3.33Å; M462-L465 PolarHBondContact O-N 3.43Å; L465-K467 VanDerWaalsContact C-N 3.31Å; L465-K467 PolarHBondContact O-N 3.01Å; L465-E468 PolarHBondContact O-N 3.32Å; L465-F469 HydrophobicContact CB-CD2 4.39Å; L465-F469 HydrophobicContact CB-CE2 4.5Å; L465-F469 HydrophobicContact CD2-CE2 4.33Å; L465-F469 WeakPolarHBondContact O-CB 3.36Å; L465-F469 WeakPolarHBondContact O-CD2 3.46Å; L465-F469 PolarHBondContact O-N 3.06Å; L465-F476 HydrophobicContact CB-CD1 3.71Å; L465-F476 HydrophobicContact CB-CE1 3.48Å; L465-F476 VanDerWaalsContact CB-CE1 3.48Å; L465-F476 HydrophobicContact CB-CZ 4.33Å; L465-F476 HydrophobicContact CD1-CE1 3.8Å; L465-F476 HydrophobicContact CD1-CZ 4.07Å; L465-F476 HydrophobicContact CG-CE1 4.28Å; L465-V596 HydrophobicContact CD1-CG1 3.47Å; L465-V596 VanDerWaalsContact CD1-CG1 3.47Å
466Y97.8Very high97.1Very high76 Ų7649 Ų4930%0.29827%0.273SS..Hα-helixtrans-56.8-46175.2175.9-105.9000111.8M462 A463 R464 T470 K478M462-Y466 VanDerWaalsContact O-CB 3.3Å; M462-Y466 WeakPolarHBondContact O-CB 3.21Å; M462-Y466 PolarHBondContact O-N 3.25Å; A463-Y466 PolarHBondContact O-N 3.01Å; R464-Y466 VanDerWaalsContact C-N 3.34Å; R464-Y466 PolarHBondContact O-N 3.14Å; Y466-T470 VanDerWaalsContact O-CB 3.22Å; Y466-T470 WeakPolarHBondContact O-CB 3.43Å; Y466-T470 PolarHBondContact O-N 3.29Å; Y466-T470 PolarHBondContact O-OG1 2.82Å; Y466-K478 HydrophobicContact CD1-CB 4.38Å; Y466-K478 HydrophobicContact CD1-CD 4.49Å; Y466-K478 HydrophobicContact CD1-CG 4.08Å; Y466-K478 HydrophobicContact CD2-CB 3.81Å; Y466-K478 HydrophobicContact CD2-CG 4.39Å; Y466-K478 HydrophobicContact CE1-CB 4.39Å; Y466-K478 HydrophobicContact CE1-CD 3.9Å; Y466-K478 HydrophobicContact CE1-CG 3.98Å; Y466-K478 HydrophobicContact CE2-CB 3.84Å; Y466-K478 HydrophobicContact CE2-CD 4.38Å; Y466-K478 HydrophobicContact CE2-CG 4.33Å; Y466-K478 HydrophobicContact CG-CB 4.09Å; Y466-K478 HydrophobicContact CG-CG 4.28Å
467K96.7Very high97.2Very high94 Ų9449 Ų4941%0.40927%0.273SS..Hα-helixtrans-64.2-44.4178.1-177.5175.9177.9171.20112.3A463 R464 L465 A471 D495 D498A463-K467 WeakPolarHBondContact O-CB 3.12Å; A463-K467 PolarHBondContact O-N 3.32Å; R464-K467 WeakPolarHBondContact O-CB 3.22Å; R464-K467 PolarHBondContact O-N 2.79Å; R464-K467 VanDerWaalsContact O-N 3.17Å; L465-K467 VanDerWaalsContact C-N 3.31Å; L465-K467 PolarHBondContact O-N 3.01Å; K467-A471 WeakPolarHBondContact O-CB 3.48Å; K467-A471 PolarHBondContact O-N 2.91Å; K467-D495 IonicContact NZ-OD2 2.96Å; K467-D495 PolarHBondContact NZ-OD2 3.21Å; K467-D498 IonicContact NZ-OD2 2.59Å; K467-D498 PolarHBondContact NZ-OD2 3.47Å
468E97.3Very high97.2Very high115 Ų11548.7 Ų48.754%0.53727%0.269SS..Hα-helixtrans-62.8-52.9178.1-73.3172.4-170.100111.8R464 L465 T470 A471 D472R464-E468 WeakPolarHBondContact O-CG 3.3Å; R464-E468 PolarHBondContact O-N 3.45Å; L465-E468 PolarHBondContact O-N 3.32Å; E468-T470 VanDerWaalsContact C-N 3.33Å; E468-T470 PolarHBondContact O-N 3.39Å; E468-A471 WeakPolarHBondContact O-CB 3.37Å; E468-A471 PolarHBondContact O-N 3Å; E468-D472 PolarHBondContact O-N 3.28Å
469F97.6Very high97.3Very high55 Ų5549 Ų4924%0.24127%0.271CS..Hα-helixtrans-61.5-41177.9-80.3-68.6000112.2L465 A471 D472 G473 S474 F476 K603L465-F469 HydrophobicContact CB-CD2 4.39Å; L465-F469 HydrophobicContact CB-CE2 4.5Å; L465-F469 HydrophobicContact CD2-CE2 4.33Å; L465-F469 WeakPolarHBondContact O-CB 3.36Å; L465-F469 WeakPolarHBondContact O-CD2 3.46Å; L465-F469 PolarHBondContact O-N 3.06Å; F469-A471 VanDerWaalsContact C-N 3.33Å; F469-A471 PolarHBondContact O-N 3.39Å; F469-D472 PolarHBondContact O-N 3Å; F469-G473 PolarHBondContact O-N 2.92Å; F469-S474 CarbonylContact C-O 3.54Å; F469-S474 VanDerWaalsContact C-O 3.28Å; F469-S474 CarbonylContact O-C 3.59Å; F469-S474 WeakPolarHBondContact O-CA 3.24Å; F469-S474 WeakPolarHBondContact O-CB 3.37Å; F469-S474 PolarHBondContact O-N 3.35Å; F469-F476 HydrophobicContact CB-CB 3.81Å; F469-F476 HydrophobicContact CD2-CB 3.63Å; F469-F476 HydrophobicContact CD2-CD1 4.01Å; F469-F476 AromaticContact CD2-CD2 3.65Å; F469-F476 HydrophobicContact CD2-CD2 3.65Å; F469-F476 HydrophobicContact CD2-CE2 4.29Å; F469-F476 AromaticContact CD2-CG 3.48Å; F469-F476 HydrophobicContact CD2-CG 3.48Å; F469-F476 VanDerWaalsContact CD2-CG 3.48Å; F469-F476 HydrophobicContact CE2-CD1 4.39Å; F469-F476 AromaticContact CE2-CD2 3.67Å; F469-F476 HydrophobicContact CE2-CD2 3.67Å; F469-F476 AromaticContact CE2-CE2 3.88Å; F469-F476 HydrophobicContact CE2-CE2 3.88Å; F469-F476 AromaticContact CE2-CG 3.94Å; F469-F476 HydrophobicContact CE2-CG 3.94Å; F469-F476 HydrophobicContact CE2-CZ 4.32Å; F469-F476 HydrophobicContact CG-CB 3.94Å; F469-F476 HydrophobicContact CG-CD2 4.43Å; F469-F476 HydrophobicContact CG-CG 4.27Å; F469-F476 HydrophobicContact CZ-CD2 4.45Å; F469-K603 HydrophobicContact CD1-CD 4.42Å; F469-K603 HydrophobicContact CE1-CD 4.16Å; F469-K603 HydrophobicContact CZ-CD 4.3Å
470T95.6Very high97.3Very high67 Ų6749.1 Ų49.141%0.41127%0.271SS..Hα-helixtrans-64.8-37.8177.9-55.20000111.5Y466 E468 D472 G473 S474Y466-T470 VanDerWaalsContact O-CB 3.22Å; Y466-T470 WeakPolarHBondContact O-CB 3.43Å; Y466-T470 PolarHBondContact O-N 3.29Å; Y466-T470 PolarHBondContact O-OG1 2.82Å; E468-T470 VanDerWaalsContact C-N 3.33Å; E468-T470 PolarHBondContact O-N 3.39Å; T470-D472 PolarHBondContact O-N 3.48Å; T470-G473 PolarHBondContact O-N 3.26Å; T470-S474 WeakPolarHBondContact CA-O 3.3Å; T470-S474 PolarHBondContact N-O 3.24Å
471A96.6Very high97.2Very high85 Ų8549.4 Ų49.470%0.70227%0.273SS*.Hα-helixtrans-63.5-31.1175.800000112.7K467 E468 F469 G473K467-A471 WeakPolarHBondContact O-CB 3.48Å; K467-A471 PolarHBondContact O-N 2.91Å; E468-A471 WeakPolarHBondContact O-CB 3.37Å; E468-A471 PolarHBondContact O-N 3Å; F469-A471 VanDerWaalsContact C-N 3.33Å; F469-A471 PolarHBondContact O-N 3.39Å; A471-G473 PolarHBondContact O-N 2.95Å
472D96.5Very high97.2Very high141 Ų14149.1 Ų49.175%0.75427%0.269SS*.THydrogen-bonded Turntrans-82.55.2174.3-70.7-18.2000113.4E468 F469 T470 S474E468-D472 PolarHBondContact O-N 3.28Å; F469-D472 PolarHBondContact O-N 3Å; T470-D472 PolarHBondContact O-N 3.48Å; D472-S474 VanDerWaalsContact C-N 3.27Å; D472-S474 PolarHBondContact O-N 3.33Å
473G95.9Very high97.1Very high76 Ų7653.5 Ų53.578%0.78429%0.289SS*.THydrogen-bonded Turntrans71.920.9-177.900000113.8F469 T470 A471F469-G473 PolarHBondContact O-N 2.92Å; T470-G473 PolarHBondContact O-N 3.26Å; A471-G473 PolarHBondContact O-N 2.95Å
474S96.6Very high97Very high40 Ų4056.7 Ų56.728%0.2831%0.308SS..  trans-109.1159.5178.3171.60000111.1F469 T470 D472 K603F469-S474 CarbonylContact C-O 3.54Å; F469-S474 VanDerWaalsContact C-O 3.28Å; F469-S474 CarbonylContact O-C 3.59Å; F469-S474 WeakPolarHBondContact O-CA 3.24Å; F469-S474 WeakPolarHBondContact O-CB 3.37Å; F469-S474 PolarHBondContact O-N 3.35Å; T470-S474 WeakPolarHBondContact CA-O 3.3Å; T470-S474 PolarHBondContact N-O 3.24Å; D472-S474 VanDerWaalsContact C-N 3.27Å; D472-S474 PolarHBondContact O-N 3.33Å; S474-K603 WeakPolarHBondContact OG-CE 3.23Å; S474-K603 PolarHBondContact OG-NZ 3.06Å
475W97.1Very high97Very high56 Ų5652 Ų5221%0.21229%0.29CS..  trans-86.2154.8173.872.7-86.5000112F477 P542 V555 F602 K603 Y606 D607W475-F477 HydrophobicContact CH2-CE2 4.46Å; W475-F477 HydrophobicContact CH2-CZ 4.18Å; W475-F477 HydrophobicContact CZ3-CE1 4.14Å; W475-F477 HydrophobicContact CZ3-CE2 4.15Å; W475-F477 AromaticContact CZ3-CZ 3.91Å; W475-F477 HydrophobicContact CZ3-CZ 3.91Å; W475-P542 HydrophobicContact CB-CG 4.36Å; W475-P542 HydrophobicContact CD2-CG 4.13Å; W475-P542 HydrophobicContact CE3-CG 3.58Å; W475-P542 HydrophobicContact CG-CG 4.48Å; W475-P542 HydrophobicContact CZ3-CG 4.21Å; W475-V555 HydrophobicContact CD2-CG2 4.32Å; W475-V555 HydrophobicContact CE3-CG2 4.14Å; W475-V555 HydrophobicContact CH2-CG1 4.23Å; W475-V555 HydrophobicContact CH2-CG2 3.79Å; W475-V555 HydrophobicContact CZ2-CG2 3.99Å; W475-V555 HydrophobicContact CZ3-CB 4.4Å; W475-V555 HydrophobicContact CZ3-CG1 4.41Å; W475-V555 HydrophobicContact CZ3-CG2 3.87Å; W475-F602 HydrophobicContact CH2-CD1 4.09Å; W475-F602 AromaticContact CH2-CE1 3.93Å; W475-F602 HydrophobicContact CH2-CE1 3.93Å; W475-K603 HydrophobicContact CH2-CB 4.11Å; W475-K603 HydrophobicContact CH2-CG 4.31Å; W475-K603 HydrophobicContact CZ2-CB 4.09Å; W475-K603 HydrophobicContact CZ2-CD 4.38Å; W475-K603 HydrophobicContact CZ2-CG 3.86Å; W475-K603 VanDerWaalsContact NE1-NZ 3.18Å; W475-K603 WeakPolarHBondContact O-CD 3.35Å; W475-K603 WeakPolarHBondContact O-CE 3.41Å; W475-K603 PolarHBondContact O-NZ 3.35Å; W475-Y606 HydrophobicContact CH2-CD1 4.42Å; W475-Y606 AromaticContact CZ2-CD1 3.59Å; W475-Y606 HydrophobicContact CZ2-CD1 3.59Å; W475-Y606 HydrophobicContact CZ2-CE1 4.25Å; W475-Y606 HydrophobicContact CZ2-CG 4.18Å; W475-D607 PolarHBondContact NE1-OD1 2.93Å
476F98Very high96.9Very high5 Ų553.2 Ų53.22%0.02230%0.299CS..  trans-155.9174.6163.8-161.9-118.3000110.6M462 L465 F469 L599 K603M462-F476 HydrophobicContact CE-CD1 4.2Å; M462-F476 HydrophobicContact CE-CE1 3.53Å; M462-F476 HydrophobicContact CE-CZ 4.22Å; M462-F476 HydrophobicContact SD-CE1 4.24Å; L465-F476 HydrophobicContact CB-CD1 3.71Å; L465-F476 HydrophobicContact CB-CE1 3.48Å; L465-F476 VanDerWaalsContact CB-CE1 3.48Å; L465-F476 HydrophobicContact CB-CZ 4.33Å; L465-F476 HydrophobicContact CD1-CE1 3.8Å; L465-F476 HydrophobicContact CD1-CZ 4.07Å; L465-F476 HydrophobicContact CG-CE1 4.28Å; F469-F476 HydrophobicContact CB-CB 3.81Å; F469-F476 HydrophobicContact CD2-CB 3.63Å; F469-F476 HydrophobicContact CD2-CD1 4.01Å; F469-F476 AromaticContact CD2-CD2 3.65Å; F469-F476 HydrophobicContact CD2-CD2 3.65Å; F469-F476 HydrophobicContact CD2-CE2 4.29Å; F469-F476 AromaticContact CD2-CG 3.48Å; F469-F476 HydrophobicContact CD2-CG 3.48Å; F469-F476 VanDerWaalsContact CD2-CG 3.48Å; F469-F476 HydrophobicContact CE2-CD1 4.39Å; F469-F476 AromaticContact CE2-CD2 3.67Å; F469-F476 HydrophobicContact CE2-CD2 3.67Å; F469-F476 AromaticContact CE2-CE2 3.88Å; F469-F476 HydrophobicContact CE2-CE2 3.88Å; F469-F476 AromaticContact CE2-CG 3.94Å; F469-F476 HydrophobicContact CE2-CG 3.94Å; F469-F476 HydrophobicContact CE2-CZ 4.32Å; F469-F476 HydrophobicContact CG-CB 3.94Å; F469-F476 HydrophobicContact CG-CD2 4.43Å; F469-F476 HydrophobicContact CG-CG 4.27Å; F469-F476 HydrophobicContact CZ-CD2 4.45Å; F476-L599 HydrophobicContact CZ-CB 4.44Å; F476-K603 HydrophobicContact CD2-CD 3.66Å; F476-K603 HydrophobicContact CE2-CD 4.24Å
477F98.1Very high96.9Very high0 Ų050.5 Ų50.50%029%0.29CS..PPolyproline II helixtrans-74.7133.6176.4-55.5-77.9000111.5M462 W475 I539 L540 A541 V560 L599 F602M462-F477 HydrophobicContact CE-CB 3.66Å; W475-F477 HydrophobicContact CH2-CE2 4.46Å; W475-F477 HydrophobicContact CH2-CZ 4.18Å; W475-F477 HydrophobicContact CZ3-CE1 4.14Å; W475-F477 HydrophobicContact CZ3-CE2 4.15Å; W475-F477 AromaticContact CZ3-CZ 3.91Å; W475-F477 HydrophobicContact CZ3-CZ 3.91Å; F477-I539 HydrophobicContact CB-CB 4.42Å; F477-I539 HydrophobicContact CB-CD1 4.26Å; F477-I539 HydrophobicContact CD1-CD1 4.37Å; F477-I539 HydrophobicContact CG-CD1 4.24Å; F477-L540 CarbonylContact C-O 3.38Å; F477-L540 VanDerWaalsContact CA-O 3.31Å; F477-L540 WeakPolarHBondContact CA-O 3.49Å; F477-A541 HydrophobicContact CD1-CB 4.03Å; F477-A541 HydrophobicContact CE1-CB 3.94Å; F477-V560 HydrophobicContact CE1-CG1 4.08Å; F477-V560 HydrophobicContact CE1-CG2 3.84Å; F477-V560 HydrophobicContact CZ-CG1 3.84Å; F477-V560 HydrophobicContact CZ-CG2 3.92Å; F477-L599 HydrophobicContact CD2-CB 4.04Å; F477-L599 HydrophobicContact CD2-CD1 4.43Å; F477-L599 HydrophobicContact CD2-CD2 3.97Å; F477-L599 HydrophobicContact CD2-CG 4.36Å; F477-L599 HydrophobicContact CE2-CB 3.98Å; F477-L599 HydrophobicContact CE2-CD2 3.71Å; F477-L599 HydrophobicContact CE2-CG 4.37Å; F477-L599 HydrophobicContact CZ-CD2 4.14Å; F477-F602 HydrophobicContact CE2-CD1 4.3Å; F477-F602 AromaticContact CZ-CD1 3.81Å; F477-F602 HydrophobicContact CZ-CD1 3.81Å; F477-F602 HydrophobicContact CZ-CE1 4.16Å
478K97.5Very high96.7Very high47 Ų4749.6 Ų49.620%0.20429%0.293CS..EExtended strand (participates in β ladder)trans-100.4132.8179-176.6179.4-179.1173.20110.4Y466 E483 I539 L540Y466-K478 HydrophobicContact CD1-CB 4.38Å; Y466-K478 HydrophobicContact CD1-CD 4.49Å; Y466-K478 HydrophobicContact CD1-CG 4.08Å; Y466-K478 HydrophobicContact CD2-CB 3.81Å; Y466-K478 HydrophobicContact CD2-CG 4.39Å; Y466-K478 HydrophobicContact CE1-CB 4.39Å; Y466-K478 HydrophobicContact CE1-CD 3.9Å; Y466-K478 HydrophobicContact CE1-CG 3.98Å; Y466-K478 HydrophobicContact CE2-CB 3.84Å; Y466-K478 HydrophobicContact CE2-CD 4.38Å; Y466-K478 HydrophobicContact CE2-CG 4.33Å; Y466-K478 HydrophobicContact CG-CB 4.09Å; Y466-K478 HydrophobicContact CG-CG 4.28Å; K478-E483 WeakPolarHBondContact CE-OE1 3.5Å; K478-E483 IonicContact NZ-OE1 3.76Å; K478-E483 PolarHBondContact NZ-OE1 3.02Å; K478-I539 CarbonylContact O-C 3.48Å; K478-I539 WeakPolarHBondContact O-CA 3.37Å; K478-L540 HydrophobicContact CB-CB 4.45Å; K478-L540 PolarHBondContact N-O 3.18Å; K478-L540 PolarHBondContact O-N 2.95Å
479P97.8Very high96.6Very high6 Ų652.2 Ų52.24%0.03931%0.306CS..EExtended strand (participates in β ladder)trans-70.5138.9172.331.7-34.7000110.5M462 A463 N481M462-P479 HydrophobicContact CB-CB 4.21Å; M462-P479 HydrophobicContact CB-CG 4.2Å; A463-P479 HydrophobicContact CB-CG 3.9Å; P479-N481 WeakPolarHBondContact CB-OD1 3.5Å; P479-N481 PolarHBondContact O-N 3.36Å
480W97.8Very high96.5Very high3 Ų354 Ų541%0.01132%0.321CS..SBendtrans-84.493.8174.2-172.564000109.8I282 V327 R459 M513 W519 H520 F522 L532 S538 L540I282-W480 HydrophobicContact CD1-CD2 3.67Å; I282-W480 HydrophobicContact CD1-CE3 3.96Å; I282-W480 HydrophobicContact CD1-CG 4.16Å; I282-W480 HydrophobicContact CD1-CH2 4.26Å; I282-W480 HydrophobicContact CD1-CZ2 3.99Å; I282-W480 HydrophobicContact CD1-CZ3 4.23Å; I282-W480 HydrophobicContact CG2-CH2 3.64Å; I282-W480 HydrophobicContact CG2-CZ2 4.08Å; I282-W480 HydrophobicContact CG2-CZ3 3.98Å; V327-W480 HydrophobicContact CG2-CH2 4.29Å; R459-W480 PolarHBondContact NH1-O 3.17Å; W480-M513 HydrophobicContact CH2-CE 4.19Å; W480-W519 HydrophobicContact CD2-CZ3 4.14Å; W480-W519 AromaticContact CE2-CZ3 3.91Å; W480-W519 HydrophobicContact CZ2-CZ3 4.16Å; W480-W519 PolarHBondContact NE1-O 3.18Å; W480-H520 HydrophobicContact CZ2-CB 4.1Å; W480-F522 HydrophobicContact CH2-CE2 4.08Å; W480-F522 HydrophobicContact CH2-CZ 4.45Å; W480-F522 AromaticContact CZ2-CE2 4Å; W480-F522 HydrophobicContact CZ2-CE2 4Å; W480-F522 HydrophobicContact CZ2-CZ 4.42Å; W480-L532 HydrophobicContact CE3-CD1 4.03Å; W480-L532 HydrophobicContact CE3-CD2 4.31Å; W480-L532 HydrophobicContact CH2-CD1 4.37Å; W480-L532 HydrophobicContact CZ3-CD1 3.52Å; W480-L532 HydrophobicContact CZ3-CD2 4.45Å; W480-L532 WeakPolarHBondContact O-CD2 3.4Å; W480-S538 PolarHBondContact N-O 3.03Å; W480-L540 HydrophobicContact CB-CD1 4.18Å; W480-L540 HydrophobicContact CB-CD2 4.21Å; W480-L540 HydrophobicContact CB-CG 4.05Å; W480-L540 HydrophobicContact CG-CD1 4.41Å; W480-L540 HydrophobicContact CG-CD2 4.49Å
481N97.4Very high96.5Very high7 Ų753.3 Ų53.34%0.03733%0.328CS..SBendtrans-161180172.848.5-116.5000109.8R459 P479 F496 W511 W519 L532R459-N481 PolarHBondContact NH1-OD1 3.11Å; P479-N481 WeakPolarHBondContact CB-OD1 3.5Å; P479-N481 PolarHBondContact O-N 3.36Å; N481-F496 HydrophobicContact CB-CE2 4.45Å; N481-W511 HydrophobicContact CB-CZ3 4.14Å; N481-W519 VanDerWaalsContact CA-CZ3 3.46Å; N481-L532 HydrophobicContact CB-CD2 4.13Å
482K96.5Very high96.5Very high9 Ų954.7 Ų54.74%0.03932%0.318CS..  trans-52.4138.6168.4-71.1-171.5-178.1-176.50111V485 F496 D509 C510 V512 H514 E517 W519K482-V485 HydrophobicContact CB-CG1 4.11Å; K482-V485 HydrophobicContact CD-CG1 4.32Å; K482-F496 WeakPolarHBondContact O-CB 3.23Å; K482-F496 WeakPolarHBondContact O-CD2 3.42Å; K482-F496 WeakPolarHBondContact O-CG 3.31Å; K482-D509 PolarHBondContact NZ-O 3.43Å; K482-C510 WeakPolarHBondContact CD-O 3.28Å; K482-V512 WeakPolarHBondContact CE-O 2.94Å; K482-V512 PolarHBondContact NZ-O 3.29Å; K482-H514 PolarHBondContact NZ-CD2 3.2Å; K482-H514 PolarHBondContact NZ-NE2 2.88Å; K482-H514 VanDerWaalsContact NZ-NE2 3.11Å; K482-E517 VanDerWaalsContact CE-OE1 3.3Å; K482-E517 WeakPolarHBondContact CE-OE1 3.35Å; K482-E517 VanDerWaalsContact CE-OE2 3.3Å; K482-E517 WeakPolarHBondContact CE-OE2 3.42Å; K482-E517 IonicContact NZ-OE1 3.43Å; K482-E517 PolarHBondContact NZ-OE1 3.49Å; K482-E517 IonicContact NZ-OE2 2.66Å; K482-W519 HydrophobicContact CG-CD2 4.43Å; K482-W519 HydrophobicContact CG-CZ2 3.98Å
483E94.7Very high96.5Very high92 Ų9252.2 Ų52.243%0.4331%0.308SS..SBendtrans-85.2-30.2173.3-64.9179.4-16700112.2K478 F496K478-E483 WeakPolarHBondContact CE-OE1 3.5Å; K478-E483 IonicContact NZ-OE1 3.76Å; K478-E483 PolarHBondContact NZ-OE1 3.02Å; E483-F496 WeakPolarHBondContact O-CB 3.41Å; E483-F496 PolarHBondContact O-N 2.99Å
484V96.5Very high96.6Very high80 Ų8050.6 Ų50.649%0.48528%0.279SS..EExtended strand (participates in β ladder)trans-128134177.6178.30000108Y494V484-Y494 CarbonylContact C-O 3.59Å; V484-Y494 VanDerWaalsContact CA-O 3.28Å; V484-Y494 WeakPolarHBondContact CA-O 3.45Å; V484-Y494 WeakPolarHBondContact CG1-O 3.43Å
485V97.2Very high96.6Very high2 Ų251.7 Ų51.71%0.01228%0.281CS..EExtended strand (participates in β ladder)trans-118146.1174.7-63.90000109.8K482 T493 Y494 F496 A499 L503 L504 C510K482-V485 HydrophobicContact CB-CG1 4.11Å; K482-V485 HydrophobicContact CD-CG1 4.32Å; V485-T493 CarbonylContact O-C 3.6Å; V485-T493 WeakPolarHBondContact O-CA 3.37Å; V485-Y494 PolarHBondContact N-O 2.92Å; V485-Y494 PolarHBondContact O-N 2.96Å; V485-F496 HydrophobicContact CG1-CD2 3.98Å; V485-A499 HydrophobicContact CG2-CB 3.56Å; V485-L503 HydrophobicContact CG2-CD2 4.39Å; V485-L504 HydrophobicContact CB-CD2 4.37Å; V485-L504 HydrophobicContact CG1-CD2 3.94Å; V485-L504 HydrophobicContact CG2-CD2 3.92Å; V485-C510 HydrophobicContact CG1-CB 4.31Å
486T96.6Very high96.7Very high61 Ų6149.1 Ų49.137%0.37427%0.272SS..EExtended strand (participates in β ladder)trans-111130.3175.6-52.80000108.4P488 T493T486-P488 VanDerWaalsContact O-CD 3.26Å; T486-P488 WeakPolarHBondContact O-CD 3.23Å; T486-T493 HydrophobicContact CG2-CG2 4.14Å
487D96.4Very high96.6Very high20 Ų2048.9 Ų48.911%0.10727%0.27CS..  trans-74.7113.1169173.4-1.2000109Q489 T490 G491 K492 Y494 L503D487-Q489 PolarHBondContact O-N 3.02Å; D487-Q489 WeakPolarHBondContact OD1-CB 3.46Å; D487-Q489 PolarHBondContact OD1-N 3.47Å; D487-T490 WeakPolarHBondContact CB-OG1 3.46Å; D487-T490 PolarHBondContact O-N 2.87Å; D487-T490 VanDerWaalsContact OD2-CG2 3.26Å; D487-T490 WeakPolarHBondContact OD2-CG2 3.48Å; D487-T490 PolarHBondContact OD2-OG1 3.35Å; D487-G491 VanDerWaalsContact O-CA 3.3Å; D487-G491 WeakPolarHBondContact O-CA 3.41Å; D487-G491 PolarHBondContact O-N 2.91Å; D487-K492 PolarHBondContact N-O 3.44Å; D487-Y494 HydrophobicContact CB-CE2 4.18Å; D487-L503 HydrophobicContact CB-CD1 3.86Å; D487-L503 HydrophobicContact CB-CD2 3.9Å
488P94Very high96.6Very high74 Ų7453.4 Ų53.448%0.48130%0.295SS..THydrogen-bonded Turntrans-66.5-19.8-176.927.8-35.2000113T486 V507 D509T486-P488 VanDerWaalsContact O-CD 3.26Å; T486-P488 WeakPolarHBondContact O-CD 3.23Å; P488-V507 HydrophobicContact CG-CG1 3.67Å; P488-D509 HydrophobicContact CG-CB 4.47Å
489Q93.6Very high96.6Very high171 Ų17151.3 Ų51.380%0.79929%0.286SS*.THydrogen-bonded Turntrans-81.1-36.7178.9-59.5-175.85.100112.3D487D487-Q489 PolarHBondContact O-N 3.02Å; D487-Q489 WeakPolarHBondContact OD1-CB 3.46Å; D487-Q489 PolarHBondContact OD1-N 3.47Å
490T95.6Very high96.6Very high92 Ų9253.8 Ų53.856%0.56430%0.302SS*.THydrogen-bonded Turntrans-106.2-15.9-175.7640000113.9D487 K492D487-T490 WeakPolarHBondContact CB-OG1 3.46Å; D487-T490 PolarHBondContact O-N 2.87Å; D487-T490 VanDerWaalsContact OD2-CG2 3.26Å; D487-T490 WeakPolarHBondContact OD2-CG2 3.48Å; D487-T490 PolarHBondContact OD2-OG1 3.35Å; T490-K492 PolarHBondContact O-N 3.22Å; T490-K492 WeakPolarHBondContact OG1-CB 3.39Å; T490-K492 PolarHBondContact OG1-N 3.36Å
491G95.6Very high96.6Very high53 Ų5356.1 Ų56.155%0.54632%0.317SS..  trans69.55.3-170.900000113.9D487D487-G491 VanDerWaalsContact O-CA 3.3Å; D487-G491 WeakPolarHBondContact O-CA 3.41Å; D487-G491 PolarHBondContact O-N 2.91Å
492K96.8Very high96.5Very high113 Ų11362.3 Ų62.349%0.49134%0.343SS..  trans-79.6131.7-177.8-177169.3162.8-1540110.4D487 T490 Y494D487-K492 PolarHBondContact N-O 3.44Å; T490-K492 PolarHBondContact O-N 3.22Å; T490-K492 WeakPolarHBondContact OG1-CB 3.39Å; T490-K492 PolarHBondContact OG1-N 3.36Å; K492-Y494 HydrophobicContact CB-CE2 3.98Å; K492-Y494 HydrophobicContact CD-CE1 4.07Å; K492-Y494 HydrophobicContact CD-CE2 4.15Å; K492-Y494 VanDerWaalsContact CD-OH 3.25Å; K492-Y494 WeakPolarHBondContact CD-OH 3.33Å; K492-Y494 VanDerWaalsContact CE-CZ 3.44Å; K492-Y494 WeakPolarHBondContact CE-OH 3.5Å; K492-Y494 HydrophobicContact CG-CD2 4.43Å; K492-Y494 HydrophobicContact CG-CE1 4.33Å; K492-Y494 HydrophobicContact CG-CE2 3.78Å; K492-Y494 VanDerWaalsContact NZ-CE1 3.33Å; K492-Y494 PolarHBondContact NZ-OH 3.1Å; K492-Y494 VanDerWaalsContact NZ-OH 3.15Å; K492-Y494 WeakPolarHBondContact O-CD2 3.25Å; K492-Y494 WeakPolarHBondContact O-CE2 3.31Å
493T97.4Very high96.6Very high89 Ų8962.7 Ų62.755%0.54635%0.345SS..EExtended strand (participates in β ladder)trans-92.6146.8175.459.30000111.2V485 T486V485-T493 CarbonylContact O-C 3.6Å; V485-T493 WeakPolarHBondContact O-CA 3.37Å; T486-T493 HydrophobicContact CG2-CG2 4.14Å
494Y97.9Very high96.8Very high43 Ų4358.3 Ų58.317%0.16933%0.325CS..EExtended strand (participates in β ladder)trans-136.1141.7178.5-59.7-93.7000109.4V484 V485 D487 K492 F496 A499 P500 L503V484-Y494 CarbonylContact C-O 3.59Å; V484-Y494 VanDerWaalsContact CA-O 3.28Å; V484-Y494 WeakPolarHBondContact CA-O 3.45Å; V484-Y494 WeakPolarHBondContact CG1-O 3.43Å; V485-Y494 PolarHBondContact N-O 2.92Å; V485-Y494 PolarHBondContact O-N 2.96Å; D487-Y494 HydrophobicContact CB-CE2 4.18Å; K492-Y494 HydrophobicContact CB-CE2 3.98Å; K492-Y494 HydrophobicContact CD-CE1 4.07Å; K492-Y494 HydrophobicContact CD-CE2 4.15Å; K492-Y494 VanDerWaalsContact CD-OH 3.25Å; K492-Y494 WeakPolarHBondContact CD-OH 3.33Å; K492-Y494 VanDerWaalsContact CE-CZ 3.44Å; K492-Y494 WeakPolarHBondContact CE-OH 3.5Å; K492-Y494 HydrophobicContact CG-CD2 4.43Å; K492-Y494 HydrophobicContact CG-CE1 4.33Å; K492-Y494 HydrophobicContact CG-CE2 3.78Å; K492-Y494 VanDerWaalsContact NZ-CE1 3.33Å; K492-Y494 PolarHBondContact NZ-OH 3.1Å; K492-Y494 VanDerWaalsContact NZ-OH 3.15Å; K492-Y494 WeakPolarHBondContact O-CD2 3.25Å; K492-Y494 WeakPolarHBondContact O-CE2 3.31Å; Y494-F496 PolarHBondContact O-N 3.27Å; Y494-A499 HydrophobicContact CG-CB 4.29Å; Y494-P500 HydrophobicContact CE1-CG 4.09Å; Y494-L503 HydrophobicContact CD2-CD2 4.08Å; Y494-L503 HydrophobicContact CE2-CD2 4.17Å
495D97.1Very high96.8Very high62 Ų6254.6 Ų54.633%0.33230%0.303SS..EExtended strand (participates in β ladder)trans-58.1133.6156.6-177.2-44.8000107.8K467 A497 D498 A499K467-D495 IonicContact NZ-OD2 2.96Å; K467-D495 PolarHBondContact NZ-OD2 3.21Å; D495-A497 PolarHBondContact O-N 3.34Å; D495-A497 VanDerWaalsContact O-N 3.16Å; D495-A497 VanDerWaalsContact OD1-CB 3.23Å; D495-A497 WeakPolarHBondContact OD1-CB 3.47Å; D495-A497 PolarHBondContact OD1-N 2.96Å; D495-D498 HydrophobicContact CB-CB 4.48Å; D495-D498 CarbonylContact O-C 3.52Å; D495-D498 PolarHBondContact O-N 3.3Å; D495-A499 PolarHBondContact O-N 2.62Å
496F97.9Very high96.8Very high3 Ų357.3 Ų57.31%0.01332%0.319CS..G310 helixtrans-53.4-37.8-177.5-178.7-83.4000112.4R459 Q460 A463 N481 K482 E483 V485 Y494 D498 A499 L504 W511R459-F496 HydrophobicContact CB-CE1 3.71Å; R459-F496 HydrophobicContact CB-CZ 3.89Å; Q460-F496 HydrophobicContact CG-CD1 4.37Å; Q460-F496 HydrophobicContact CG-CE1 3.9Å; Q460-F496 PolarHBondContact NE2-O 2.74Å; A463-F496 HydrophobicContact CB-CD1 4.12Å; N481-F496 HydrophobicContact CB-CE2 4.45Å; K482-F496 WeakPolarHBondContact O-CB 3.23Å; K482-F496 WeakPolarHBondContact O-CD2 3.42Å; K482-F496 WeakPolarHBondContact O-CG 3.31Å; E483-F496 WeakPolarHBondContact O-CB 3.41Å; E483-F496 PolarHBondContact O-N 2.99Å; V485-F496 HydrophobicContact CG1-CD2 3.98Å; Y494-F496 PolarHBondContact O-N 3.27Å; F496-D498 PolarHBondContact O-N 2.83Å; F496-A499 PolarHBondContact O-N 2.87Å; F496-L504 HydrophobicContact CD2-CD1 4.29Å; F496-L504 HydrophobicContact CD2-CD2 3.98Å; F496-L504 HydrophobicContact CE1-CD1 4.34Å; F496-L504 HydrophobicContact CE2-CD1 3.89Å; F496-L504 HydrophobicContact CE2-CD2 3.79Å; F496-L504 HydrophobicContact CE2-CG 4.46Å; F496-L504 HydrophobicContact CZ-CD1 3.9Å; F496-W511 AromaticContact CE2-CH2 3.75Å; F496-W511 HydrophobicContact CE2-CH2 3.75Å; F496-W511 HydrophobicContact CE2-CZ2 4.3Å; F496-W511 HydrophobicContact CE2-CZ3 4.19Å; F496-W511 AromaticContact CZ-CH2 3.76Å; F496-W511 HydrophobicContact CZ-CH2 3.76Å; F496-W511 HydrophobicContact CZ-CZ2 4.49Å; F496-W511 HydrophobicContact CZ-CZ3 4.39Å
497A97.4Very high96.9Very high0 Ų055.5 Ų55.50%031%0.308CS..G310 helixtrans-61.6-29.3178.700000113A463 R464 D495A463-A497 HydrophobicContact CB-CB 3.8Å; R464-A497 HydrophobicContact CG-CB 3.78Å; R464-A497 VanDerWaalsContact CZ-O 3.28Å; R464-A497 PolarHBondContact NE-O 3.25Å; R464-A497 PolarHBondContact NH2-O 2.8Å; D495-A497 PolarHBondContact O-N 3.34Å; D495-A497 VanDerWaalsContact O-N 3.16Å; D495-A497 VanDerWaalsContact OD1-CB 3.23Å; D495-A497 WeakPolarHBondContact OD1-CB 3.47Å; D495-A497 PolarHBondContact OD1-N 2.96Å
498D97.2Very high96.9Very high95 Ų9556.6 Ų56.651%0.50831%0.313SS..G310 helixtrans-113.50.1-172.1-58.7-44.8000112.5K467 D495 F496K467-D498 IonicContact NZ-OD2 2.59Å; K467-D498 PolarHBondContact NZ-OD2 3.47Å; D495-D498 HydrophobicContact CB-CB 4.48Å; D495-D498 CarbonylContact O-C 3.52Å; D495-D498 PolarHBondContact O-N 3.3Å; F496-D498 PolarHBondContact O-N 2.83Å
499A97.8Very high97Very high3 Ų355.8 Ų55.83%0.02530%0.304CS..SBendtrans-65.3144.4177.300000111Q460 V485 Y494 D495 F496 T501 L504Q460-A499 PolarHBondContact NE2-O 2.87Å; V485-A499 HydrophobicContact CG2-CB 3.56Å; Y494-A499 HydrophobicContact CG-CB 4.29Å; D495-A499 PolarHBondContact O-N 2.62Å; F496-A499 PolarHBondContact O-N 2.87Å; A499-T501 PolarHBondContact O-N 2.89Å; A499-L504 HydrophobicContact CB-CD1 4.11Å; A499-L504 HydrophobicContact CB-CD2 4.14Å; A499-L504 HydrophobicContact CB-CG 4.07Å
500P97.6Very high97.2Very high58 Ų5847.7 Ų47.738%0.37727%0.267SS..  trans-57.2124.7174.7-23.533.4000110.7Y494 K502 L503 L504Y494-P500 HydrophobicContact CE1-CG 4.09Å; P500-K502 PolarHBondContact O-N 2.99Å; P500-K502 VanDerWaalsContact O-N 3.15Å; P500-L503 HydrophobicContact CB-CB 4.17Å; P500-L503 WeakPolarHBondContact O-CA 3.46Å; P500-L503 VanDerWaalsContact O-CB 3.24Å; P500-L503 WeakPolarHBondContact O-CB 3.49Å; P500-L503 PolarHBondContact O-N 2.85Å; P500-L504 PolarHBondContact O-N 3.13Å
501T96.8Very high97.3Very high51 Ų5143.4 Ų43.431%0.31324%0.24SC..Hα-helixtrans-52.9-41.8-179.3-50.80000111.3V456 Q460 A499 L503 L504 T505V456-T501 HydrophobicContact CG1-CG2 4.14Å; Q460-T501 PolarHBondContact OE1-OG1 3.13Å; Q460-T501 VanDerWaalsContact OE1-OG1 3.12Å; A499-T501 PolarHBondContact O-N 2.89Å; T501-L503 VanDerWaalsContact C-N 3.26Å; T501-L503 PolarHBondContact O-N 3.04Å; T501-L504 PolarHBondContact O-N 3.12Å; T501-L504 VanDerWaalsContact O-N 3.11Å; T501-T505 HydrophobicContact CG2-CG2 3.92Å; T501-T505 VanDerWaalsContact O-CG2 3.29Å; T501-T505 WeakPolarHBondContact O-CG2 3.47Å; T501-T505 PolarHBondContact O-N 3.32Å; T501-T505 PolarHBondContact O-OG1 2.9Å
502K96.7Very high97.4Very high138 Ų13841 Ų4160%0.622%0.215SC*.Hα-helixtrans-59.4-34.4177.9-16961.2175.5174.50113.4P500 T506P500-K502 PolarHBondContact O-N 2.99Å; P500-K502 VanDerWaalsContact O-N 3.15Å; K502-T506 HydrophobicContact CD-CG2 3.85Å; K502-T506 WeakPolarHBondContact O-CB 3.2Å; K502-T506 PolarHBondContact O-N 3.48Å; K502-T506 PolarHBondContact O-OG1 2.51Å
503L97.8Very high97.4Very high16 Ų1635.7 Ų35.78%0.08419%0.192CC..Hα-helixtrans-63.6-53.3174.8174.369.1000109.4V485 D487 Y494 P500 T501 T505 T506 V507V485-L503 HydrophobicContact CG2-CD2 4.39Å; D487-L503 HydrophobicContact CB-CD1 3.86Å; D487-L503 HydrophobicContact CB-CD2 3.9Å; Y494-L503 HydrophobicContact CD2-CD2 4.08Å; Y494-L503 HydrophobicContact CE2-CD2 4.17Å; P500-L503 HydrophobicContact CB-CB 4.17Å; P500-L503 WeakPolarHBondContact O-CA 3.46Å; P500-L503 VanDerWaalsContact O-CB 3.24Å; P500-L503 WeakPolarHBondContact O-CB 3.49Å; P500-L503 PolarHBondContact O-N 2.85Å; T501-L503 VanDerWaalsContact C-N 3.26Å; T501-L503 PolarHBondContact O-N 3.04Å; L503-T505 VanDerWaalsContact C-N 3.29Å; L503-T505 PolarHBondContact O-N 2.64Å; L503-T506 PolarHBondContact O-N 3.48Å; L503-V507 HydrophobicContact CD1-CB 4.02Å; L503-V507 HydrophobicContact CD1-CG1 4.45Å; L503-V507 HydrophobicContact CD1-CG2 3.68Å; L503-V507 VanDerWaalsContact O-CB 3.31Å; L503-V507 WeakPolarHBondContact O-CB 3.23Å; L503-V507 PolarHBondContact O-N 2.92Å
504L98.3Very high97.3Very high0 Ų033.2 Ų33.20%017%0.174CC..Hα-helixtrans-61.5-34.6-179.1-63.7-179.3000112.9V456 Q460 V485 F496 A499 P500 T501 C510 W511V456-L504 HydrophobicContact CG1-CB 3.71Å; V456-L504 HydrophobicContact CG1-CD1 3.65Å; V456-L504 HydrophobicContact CG1-CG 4.35Å; V456-L504 HydrophobicContact CG2-CB 4.37Å; Q460-L504 HydrophobicContact CG-CD1 3.88Å; V485-L504 HydrophobicContact CB-CD2 4.37Å; V485-L504 HydrophobicContact CG1-CD2 3.94Å; V485-L504 HydrophobicContact CG2-CD2 3.92Å; F496-L504 HydrophobicContact CD2-CD1 4.29Å; F496-L504 HydrophobicContact CD2-CD2 3.98Å; F496-L504 HydrophobicContact CE1-CD1 4.34Å; F496-L504 HydrophobicContact CE2-CD1 3.89Å; F496-L504 HydrophobicContact CE2-CD2 3.79Å; F496-L504 HydrophobicContact CE2-CG 4.46Å; F496-L504 HydrophobicContact CZ-CD1 3.9Å; A499-L504 HydrophobicContact CB-CD1 4.11Å; A499-L504 HydrophobicContact CB-CD2 4.14Å; A499-L504 HydrophobicContact CB-CG 4.07Å; P500-L504 PolarHBondContact O-N 3.13Å; T501-L504 PolarHBondContact O-N 3.12Å; T501-L504 VanDerWaalsContact O-N 3.11Å; L504-C510 HydrophobicContact CD2-CB 4.04Å; L504-W511 HydrophobicContact CB-CZ2 4.35Å; L504-W511 PolarHBondContact O-NE1 2.87Å
505T97.7Very high97.1Very high2 Ų234.8 Ų34.81%0.01219%0.189CC..Hα-helixtrans-91.6-4.6-174.170.20000114.2Q449 I452 D453 V456 T501 L503Q449-T505 VanDerWaalsContact NE2-CB 3.33Å; Q449-T505 PolarHBondContact NE2-O 2.99Å; Q449-T505 PolarHBondContact NE2-OG1 2.91Å; I452-T505 HydrophobicContact CG2-CG2 4.06Å; D453-T505 WeakPolarHBondContact OD1-CB 3.49Å; D453-T505 WeakPolarHBondContact OD1-CG2 3.11Å; D453-T505 PolarHBondContact OD1-OG1 2.82Å; D453-T505 VanDerWaalsContact OD1-OG1 3.07Å; V456-T505 HydrophobicContact CB-CG2 3.73Å; V456-T505 HydrophobicContact CG1-CG2 3.91Å; V456-T505 HydrophobicContact CG2-CG2 3.71Å; T501-T505 HydrophobicContact CG2-CG2 3.92Å; T501-T505 VanDerWaalsContact O-CG2 3.29Å; T501-T505 WeakPolarHBondContact O-CG2 3.47Å; T501-T505 PolarHBondContact O-N 3.32Å; T501-T505 PolarHBondContact O-OG1 2.9Å; L503-T505 VanDerWaalsContact C-N 3.29Å; L503-T505 PolarHBondContact O-N 2.64Å
506T97Very high96.9Very high59 Ų5936 Ų3636%0.36222%0.216SC..Hα-helixtrans-130.4-15.7-179.3640000115.3K502 L503K502-T506 HydrophobicContact CD-CG2 3.85Å; K502-T506 WeakPolarHBondContact O-CB 3.2Å; K502-T506 PolarHBondContact O-N 3.48Å; K502-T506 PolarHBondContact O-OG1 2.51Å; L503-T506 PolarHBondContact O-N 3.48Å
507V97.7Very high96.6Very high23 Ų2338.4 Ų38.414%0.13923%0.227CC..  trans-104.8113.2-179.6178.30000110.4P488 L503 D509 C510P488-V507 HydrophobicContact CG-CG1 3.67Å; L503-V507 HydrophobicContact CD1-CB 4.02Å; L503-V507 HydrophobicContact CD1-CG1 4.45Å; L503-V507 HydrophobicContact CD1-CG2 3.68Å; L503-V507 VanDerWaalsContact O-CB 3.31Å; L503-V507 WeakPolarHBondContact O-CB 3.23Å; L503-V507 PolarHBondContact O-N 2.92Å; V507-D509 VanDerWaalsContact C-N 3.29Å; V507-D509 HydrophobicContact CG1-CB 3.99Å; V507-D509 PolarHBondContact O-N 2.77Å; V507-C510 WeakPolarHBondContact O-CB 3.21Å; V507-C510 PolarHBondContact O-N 2.85Å
508Q97.5Very high96.5Very high44 Ų4441.5 Ų41.521%0.20625%0.249CC..G310 helixtrans-56.2-39.7179.5178.7175.677.100113I360 A362 H364 C510 W511 V512 M531I360-Q508 HydrophobicContact CG1-CB 4.36Å; I360-Q508 WeakPolarHBondContact O-CB 3.43Å; I360-Q508 VanDerWaalsContact O-CG 3.26Å; I360-Q508 WeakPolarHBondContact O-CG 3.27Å; I360-Q508 PolarHBondContact O-NE2 3.48Å; A362-Q508 PolarHBondContact O-NE2 3.44Å; H364-Q508 PolarHBondContact ND1-NE2 3.27Å; Q508-C510 PolarHBondContact O-N 2.97Å; Q508-C510 VanDerWaalsContact O-N 3.08Å; Q508-W511 PolarHBondContact O-N 3.13Å; Q508-V512 HydrophobicContact CG-CG2 4.04Å; Q508-V512 PolarHBondContact O-N 2.79Å; Q508-M531 HydrophobicContact CG-CE 4.22Å; Q508-M531 HydrophobicContact CG-SD 4.11Å
509D96.6Very high96.3Very high56 Ų5638 Ų3830%0.29923%0.229SC..G310 helixtrans-58.5-24.1-177.8-164.572.1000113.7K482 P488 V507 W511 V512 H514K482-D509 PolarHBondContact NZ-O 3.43Å; P488-D509 HydrophobicContact CG-CB 4.47Å; V507-D509 VanDerWaalsContact C-N 3.29Å; V507-D509 HydrophobicContact CG1-CB 3.99Å; V507-D509 PolarHBondContact O-N 2.77Å; D509-W511 PolarHBondContact O-N 3.1Å; D509-V512 PolarHBondContact O-N 3.14Å; D509-H514 IonicContact OD1-CE1 2.64Å; D509-H514 PolarHBondContact OD1-CE1 3.07Å; D509-H514 VanDerWaalsContact OD1-CE1 3.24Å; D509-H514 IonicContact OD1-NE2 2.66Å; D509-H514 PolarHBondContact OD1-NE2 2.98Å; D509-H514 IonicContact OD2-NE2 2.71Å
510C97.6Very high96.2Very high2 Ų237.9 Ų37.91%0.01423%0.228CC..G310 helixtrans-62.5-14.8172.3-67.40000113.2K482 V485 L504 V507 Q508K482-C510 WeakPolarHBondContact CD-O 3.28Å; V485-C510 HydrophobicContact CG1-CB 4.31Å; L504-C510 HydrophobicContact CD2-CB 4.04Å; V507-C510 WeakPolarHBondContact O-CB 3.21Å; V507-C510 PolarHBondContact O-N 2.85Å; Q508-C510 PolarHBondContact O-N 2.97Å; Q508-C510 VanDerWaalsContact O-N 3.08Å
511W97.8Very high96.1Very high2 Ų236.2 Ų36.21%0.00822%0.221CC..THydrogen-bonded Turntrans-124.3-11.4-174.8-54.8100.4000114.1V456 N481 F496 L504 Q508 D509 M531 L532 P534V456-W511 HydrophobicContact CG2-CH2 4.07Å; V456-W511 HydrophobicContact CG2-CZ2 3.61Å; N481-W511 HydrophobicContact CB-CZ3 4.14Å; F496-W511 AromaticContact CE2-CH2 3.75Å; F496-W511 HydrophobicContact CE2-CH2 3.75Å; F496-W511 HydrophobicContact CE2-CZ2 4.3Å; F496-W511 HydrophobicContact CE2-CZ3 4.19Å; F496-W511 AromaticContact CZ-CH2 3.76Å; F496-W511 HydrophobicContact CZ-CH2 3.76Å; F496-W511 HydrophobicContact CZ-CZ2 4.49Å; F496-W511 HydrophobicContact CZ-CZ3 4.39Å; L504-W511 HydrophobicContact CB-CZ2 4.35Å; L504-W511 PolarHBondContact O-NE1 2.87Å; Q508-W511 PolarHBondContact O-N 3.13Å; D509-W511 PolarHBondContact O-N 3.1Å; W511-M531 HydrophobicContact CB-CB 4.48Å; W511-M531 HydrophobicContact CB-CE 4.02Å; W511-M531 CarbonylContact O-C 3.54Å; W511-M531 VanDerWaalsContact O-CA 3.27Å; W511-M531 WeakPolarHBondContact O-CA 3.32Å; W511-L532 WeakPolarHBondContact CB-O 3.36Å; W511-L532 HydrophobicContact CE3-CB 4.48Å; W511-L532 HydrophobicContact CE3-CD2 4.36Å; W511-L532 PolarHBondContact O-N 3.33Å; W511-P534 HydrophobicContact CD2-CB 4.34Å; W511-P534 HydrophobicContact CD2-CG 3.81Å; W511-P534 HydrophobicContact CE3-CG 4.39Å; W511-P534 HydrophobicContact CG-CG 4.04Å; W511-P534 HydrophobicContact CH2-CB 4.19Å; W511-P534 HydrophobicContact CZ2-CB 3.94Å; W511-P534 HydrophobicContact CZ2-CG 4.12Å
512V97.4Very high96Very high3 Ų334.2 Ų34.22%0.01821%0.208CC..BIsolated β-bridgetrans-64.5133.5174.41740000109.8K482 Q508 D509 H514 N528 M531K482-V512 WeakPolarHBondContact CE-O 2.94Å; K482-V512 PolarHBondContact NZ-O 3.29Å; Q508-V512 HydrophobicContact CG-CG2 4.04Å; Q508-V512 PolarHBondContact O-N 2.79Å; D509-V512 PolarHBondContact O-N 3.14Å; V512-H514 PolarHBondContact O-N 3.42Å; V512-N528 HydrophobicContact CG1-CB 4.38Å; V512-M531 HydrophobicContact CG2-CB 4.38Å
513M96.3Very high95.7Very high0 Ų035.7 Ų35.70%021%0.214CC..  trans-84111.4175.5-60.2-178-175.400109.3V327 W480 W519 H520 F522 I525 S530 L532V327-M513 HydrophobicContact CG1-CE 4.11Å; V327-M513 HydrophobicContact CG2-CE 3.98Å; W480-M513 HydrophobicContact CH2-CE 4.19Å; M513-W519 HydrophobicContact CE-CH2 4.09Å; M513-W519 HydrophobicContact CG-CH2 4.34Å; M513-W519 HydrophobicContact CG-CZ2 3.97Å; M513-H520 HydrophobicContact SD-CB 4.17Å; M513-F522 HydrophobicContact CE-CE2 4.32Å; M513-F522 HydrophobicContact SD-CD2 4Å; M513-F522 HydrophobicContact SD-CE2 4.18Å; M513-I525 HydrophobicContact CB-CD1 3.71Å; M513-I525 HydrophobicContact CB-CG2 4.4Å; M513-I525 HydrophobicContact CG-CD1 4.33Å; M513-I525 HydrophobicContact SD-CD1 3.72Å; M513-S530 PolarHBondContact N-O 3.46Å; M513-L532 HydrophobicContact CE-CB 4.11Å
514H95.4Very high95.3Very high38 Ų3842.2 Ų42.218%0.17625%0.249CC..  trans-94.1152.4-178.4-60.3-68.5000112.5K482 D509 V512 G516 E517 D527K482-H514 PolarHBondContact NZ-CD2 3.2Å; K482-H514 PolarHBondContact NZ-NE2 2.88Å; K482-H514 VanDerWaalsContact NZ-NE2 3.11Å; D509-H514 IonicContact OD1-CE1 2.64Å; D509-H514 PolarHBondContact OD1-CE1 3.07Å; D509-H514 VanDerWaalsContact OD1-CE1 3.24Å; D509-H514 IonicContact OD1-NE2 2.66Å; D509-H514 PolarHBondContact OD1-NE2 2.98Å; D509-H514 IonicContact OD2-NE2 2.71Å; V512-H514 PolarHBondContact O-N 3.42Å; H514-G516 PolarHBondContact O-N 2.68Å; H514-E517 HydrophobicContact CB-CG 4.18Å; H514-E517 IonicContact CD2-OE1 3.03Å; H514-E517 PolarHBondContact N-OE2 3.05Å; H514-E517 WeakPolarHBondContact O-CB 3.42Å; H514-E517 PolarHBondContact O-N 3.08Å; H514-D527 IonicContact CE1-OD1 3.79Å; H514-D527 IonicContact CG-OD1 3.6Å; H514-D527 IonicContact ND1-OD1 3.2Å; H514-D527 PolarHBondContact ND1-OD1 3.16Å
515P94.6Very high95.1Very high76 Ų7642.4 Ų42.449%0.49425%0.25SC..THydrogen-bonded Turntrans-59.6136174.2-17.729.2000111.3E517 I525 D527P515-E517 VanDerWaalsContact C-N 3.33Å; P515-I525 WeakPolarHBondContact CG-O 3.38Å; P515-D527 HydrophobicContact CG-CB 3.75Å
516G91.5Very high95Very high86 Ų8644.2 Ų44.289%0.88726%0.262SS*.THydrogen-bonded Turntrans88.3-9.4178.300000114.9H514H514-G516 PolarHBondContact O-N 2.68Å
517E93.1Very high94.9Very high54 Ų5445.7 Ų45.725%0.25227%0.268SS..  trans-72.1137.6168-66.8-175.6157.600110.7K482 H514 P515 W519 H520K482-E517 VanDerWaalsContact CE-OE1 3.3Å; K482-E517 WeakPolarHBondContact CE-OE1 3.35Å; K482-E517 VanDerWaalsContact CE-OE2 3.3Å; K482-E517 WeakPolarHBondContact CE-OE2 3.42Å; K482-E517 IonicContact NZ-OE1 3.43Å; K482-E517 PolarHBondContact NZ-OE1 3.49Å; K482-E517 IonicContact NZ-OE2 2.66Å; H514-E517 HydrophobicContact CB-CG 4.18Å; H514-E517 IonicContact CD2-OE1 3.03Å; H514-E517 PolarHBondContact N-OE2 3.05Å; H514-E517 WeakPolarHBondContact O-CB 3.42Å; H514-E517 PolarHBondContact O-N 3.08Å; P515-E517 VanDerWaalsContact C-N 3.33Å; E517-W519 PolarHBondContact OE2-NE1 2.95Å; E517-H520 PolarHBondContact O-CE1 2.83Å; E517-H520 PolarHBondContact O-NE2 2.95Å
518S93.2Very high94.7Very high65 Ų6547 Ų4746%0.45527%0.274SS..  trans-101.5-18.6-177.659.20000114.2H520 G521S518-H520 VanDerWaalsContact C-N 3.26Å; S518-H520 PolarHBondContact O-N 3.21Å; S518-G521 PolarHBondContact O-N 3.44Å
519W94.7Very high94.7Very high22 Ų2245 Ų458%0.08327%0.265CS..THydrogen-bonded Turntrans-58.5-35.7-170.970.7-93.9000113W480 N481 K482 M513 E517 L532W480-W519 HydrophobicContact CD2-CZ3 4.14Å; W480-W519 AromaticContact CE2-CZ3 3.91Å; W480-W519 HydrophobicContact CZ2-CZ3 4.16Å; W480-W519 PolarHBondContact NE1-O 3.18Å; N481-W519 VanDerWaalsContact CA-CZ3 3.46Å; K482-W519 HydrophobicContact CG-CD2 4.43Å; K482-W519 HydrophobicContact CG-CZ2 3.98Å; M513-W519 HydrophobicContact CE-CH2 4.09Å; M513-W519 HydrophobicContact CG-CH2 4.34Å; M513-W519 HydrophobicContact CG-CZ2 3.97Å; E517-W519 PolarHBondContact OE2-NE1 2.95Å; W519-L532 HydrophobicContact CH2-CB 4.12Å; W519-L532 HydrophobicContact CH2-CD2 3.87Å; W519-L532 HydrophobicContact CZ3-CD2 4Å
520H95Very high94.8Very high1 Ų142.4 Ų42.41%0.00525%0.25CS..THydrogen-bonded Turntrans-79.5-19.6-179.550.259.5000113.2N278 W480 M513 E517 S518 F522N278-H520 PolarHBondContact ND2-O 3.23Å; W480-H520 HydrophobicContact CZ2-CB 4.1Å; M513-H520 HydrophobicContact SD-CB 4.17Å; E517-H520 PolarHBondContact O-CE1 2.83Å; E517-H520 PolarHBondContact O-NE2 2.95Å; S518-H520 VanDerWaalsContact C-N 3.26Å; S518-H520 PolarHBondContact O-N 3.21Å; H520-F522 HydrophobicContact CB-CD2 3.9Å; H520-F522 HydrophobicContact CB-CE2 4.31Å; H520-F522 PolarHBondContact CE1-O 3.42Å; H520-F522 VanDerWaalsContact CE1-O 3.26Å; H520-F522 PolarHBondContact ND1-N 2.96Å; H520-F522 PolarHBondContact ND1-O 3.23Å; H520-F522 PolarHBondContact O-N 2.86Å
521G94.9Very high94.8Very high22 Ų2242.3 Ų42.323%0.22725%0.25CC..  trans72.8-3.1178.700000116.2S518S518-G521 PolarHBondContact O-N 3.44Å
522F94.6Very high94.8Very high10 Ų1042.2 Ų42.24%0.04425%0.249CC..  trans-76.7135.5168.3-53.7-61.2000111.8N278 I282 V327 W480 M513 H520N278-F522 HydrophobicContact CB-CD1 3.89Å; N278-F522 HydrophobicContact CB-CE1 3.68Å; N278-F522 HydrophobicContact CB-CZ 4.24Å; I282-F522 HydrophobicContact CG2-CZ 4.15Å; V327-F522 HydrophobicContact CG2-CE2 4.38Å; W480-F522 HydrophobicContact CH2-CE2 4.08Å; W480-F522 HydrophobicContact CH2-CZ 4.45Å; W480-F522 AromaticContact CZ2-CE2 4Å; W480-F522 HydrophobicContact CZ2-CE2 4Å; W480-F522 HydrophobicContact CZ2-CZ 4.42Å; M513-F522 HydrophobicContact CE-CE2 4.32Å; M513-F522 HydrophobicContact SD-CD2 4Å; M513-F522 HydrophobicContact SD-CE2 4.18Å; H520-F522 HydrophobicContact CB-CD2 3.9Å; H520-F522 HydrophobicContact CB-CE2 4.31Å; H520-F522 PolarHBondContact CE1-O 3.42Å; H520-F522 VanDerWaalsContact CE1-O 3.26Å; H520-F522 PolarHBondContact ND1-N 2.96Å; H520-F522 PolarHBondContact ND1-O 3.23Å; H520-F522 PolarHBondContact O-N 2.86Å
523K90.5Very high94.9Very high168 Ų16842 Ų4273%0.7325%0.248SC*.SBendtrans-86.8145.1178.2-62.3-178.3-179178.10110.3Y287 I525Y287-K523 VanDerWaalsContact CZ-O 3.28Å; Y287-K523 PolarHBondContact OH-O 3.42Å; K523-I525 PolarHBondContact O-N 3.01Å
524D91.2Very high94.9Very high154 Ų15442 Ų4282%0.82425%0.248SC*.SBendtrans52.134169.7-50.9-45.8000115.5P526D524-P526 WeakPolarHBondContact O-CD 3.35Å
525I93.8Very high95Very high3 Ų340.6 Ų40.62%0.01524%0.242CC..PPolyproline II helixtrans-65.6126.2176.3-166.6157.8000110P285 Y287 M513 P515 K523P285-I525 HydrophobicContact CG-CD1 4.09Å; Y287-I525 HydrophobicContact CE1-CB 4.41Å; M513-I525 HydrophobicContact CB-CD1 3.71Å; M513-I525 HydrophobicContact CB-CG2 4.4Å; M513-I525 HydrophobicContact CG-CD1 4.33Å; M513-I525 HydrophobicContact SD-CD1 3.72Å; P515-I525 WeakPolarHBondContact CG-O 3.38Å; K523-I525 PolarHBondContact O-N 3.01Å
526P95.4Very high95.2Very high40 Ų4037 Ų3726%0.2622%0.218SC..PPolyproline II helixtrans-67.3150.1175-15.728.8000110.9P288 D524 W529P288-P526 HydrophobicContact CG-CG 3.83Å; D524-P526 WeakPolarHBondContact O-CD 3.35Å; P526-W529 HydrophobicContact CB-CB 4.03Å; P526-W529 HydrophobicContact CG-CB 4.29Å; P526-W529 HydrophobicContact CG-CG 4.39Å; P526-W529 VanDerWaalsContact O-CB 3.27Å; P526-W529 WeakPolarHBondContact O-CB 3.42Å; P526-W529 PolarHBondContact O-N 2.9Å
527D94.8Very high95.4Very high91 Ų9132.9 Ų32.949%0.48718%0.176SC..THydrogen-bonded Turntrans-62.7140.1179.5-164.930.1000111.8H514 P515 W529H514-D527 IonicContact CE1-OD1 3.79Å; H514-D527 IonicContact CG-OD1 3.6Å; H514-D527 IonicContact ND1-OD1 3.2Å; H514-D527 PolarHBondContact ND1-OD1 3.16Å; P515-D527 HydrophobicContact CG-CB 3.75Å; D527-W529 PolarHBondContact O-N 3.26Å
528N93.9Very high95.7Very high50 Ų5030.3 Ų30.327%0.26716%0.164SC..THydrogen-bonded Turntrans51.621.7-178.3-164.748.1000115.1N330 V512N330-N528 WeakPolarHBondContact CB-O 3.43Å; N330-N528 PolarHBondContact ND2-ND2 3.22Å; N330-N528 VanDerWaalsContact ND2-ND2 3.14Å; N330-N528 PolarHBondContact ND2-O 3.2Å; V512-N528 HydrophobicContact CG1-CB 4.38Å
529W97.2Very high95.9Very high3 Ų327.2 Ų27.21%0.01114%0.143CC..SBendtrans-80.3-30176.3-178.9-115.3000112.3I286 P288 M291 Y329 N330 E333 A334 L337 P526 D527I286-W529 WeakPolarHBondContact O-CZ2 3.47Å; I286-W529 PolarHBondContact O-NE1 3.4Å; P288-W529 HydrophobicContact CG-CD2 3.7Å; P288-W529 HydrophobicContact CG-CE3 3.83Å; P288-W529 HydrophobicContact CG-CG 4.29Å; P288-W529 HydrophobicContact CG-CH2 4.05Å; P288-W529 HydrophobicContact CG-CZ2 3.91Å; P288-W529 HydrophobicContact CG-CZ3 4Å; M291-W529 HydrophobicContact CE-CH2 4.39Å; M291-W529 HydrophobicContact CE-CZ2 4.03Å; M291-W529 HydrophobicContact SD-CH2 3.86Å; M291-W529 HydrophobicContact SD-CZ2 4.01Å; Y329-W529 HydrophobicContact CD1-CZ2 4.21Å; N330-W529 PolarHBondContact N-O 3.19Å; E333-W529 HydrophobicContact CB-CE3 4.17Å; E333-W529 HydrophobicContact CB-CZ3 3.74Å; A334-W529 HydrophobicContact CB-CH2 3.95Å; A334-W529 HydrophobicContact CB-CZ3 4.5Å; L337-W529 HydrophobicContact CD1-CH2 3.8Å; L337-W529 HydrophobicContact CD1-CZ3 4.03Å; P526-W529 HydrophobicContact CB-CB 4.03Å; P526-W529 HydrophobicContact CG-CB 4.29Å; P526-W529 HydrophobicContact CG-CG 4.39Å; P526-W529 VanDerWaalsContact O-CB 3.27Å; P526-W529 WeakPolarHBondContact O-CB 3.42Å; P526-W529 PolarHBondContact O-N 2.9Å; D527-W529 PolarHBondContact O-N 3.26Å
530S97.4Very high96Very high0 Ų026.7 Ų26.70%014%0.141CC..EExtended strand (participates in β ladder)trans-149.7152.7178.8-53.90000112.1P285 C328 M513P285-S530 VanDerWaalsContact CB-OG 3.31Å; P285-S530 WeakPolarHBondContact CB-OG 3.48Å; P285-S530 WeakPolarHBondContact CG-OG 3.27Å; C328-S530 CarbonylContact O-C 3.57Å; C328-S530 WeakPolarHBondContact O-CA 3.38Å; C328-S530 WeakPolarHBondContact O-CB 3.36Å; M513-S530 PolarHBondContact N-O 3.46Å
531M97.8Very high96.2Very high0 Ų026.9 Ų26.90%014%0.143CC..EExtended strand (participates in β ladder)trans-125.8156.5170.368.5177.6-69.200110.5C328 I360 Y361 H364 Q508 W511 V512C328-M531 HydrophobicContact CB-CG 3.74Å; C328-M531 PolarHBondContact N-O 3.36Å; C328-M531 PolarHBondContact O-N 2.9Å; I360-M531 WeakPolarHBondContact O-CE 3.17Å; Y361-M531 HydrophobicContact CD1-CE 4.03Å; Y361-M531 HydrophobicContact CD1-SD 4.26Å; Y361-M531 HydrophobicContact CE1-CE 4.35Å; H364-M531 HydrophobicContact CB-SD 4.07Å; H364-M531 VanDerWaalsContact CD2-CG 3.46Å; H364-M531 WeakPolarHBondContact CD2-CG 3.46Å; Q508-M531 HydrophobicContact CG-CE 4.22Å; Q508-M531 HydrophobicContact CG-SD 4.11Å; W511-M531 HydrophobicContact CB-CB 4.48Å; W511-M531 HydrophobicContact CB-CE 4.02Å; W511-M531 CarbonylContact O-C 3.54Å; W511-M531 VanDerWaalsContact O-CA 3.27Å; W511-M531 WeakPolarHBondContact O-CA 3.32Å; V512-M531 HydrophobicContact CG2-CB 4.38Å
532L98.4Very high96.3Very high0 Ų027.3 Ų27.30%014%0.142CC..EExtended strand (participates in β ladder)trans-85.4126.1168.6178.462.7000110.1W480 N481 W511 M513 W519 P534W480-L532 HydrophobicContact CE3-CD1 4.03Å; W480-L532 HydrophobicContact CE3-CD2 4.31Å; W480-L532 HydrophobicContact CH2-CD1 4.37Å; W480-L532 HydrophobicContact CZ3-CD1 3.52Å; W480-L532 HydrophobicContact CZ3-CD2 4.45Å; W480-L532 WeakPolarHBondContact O-CD2 3.4Å; N481-L532 HydrophobicContact CB-CD2 4.13Å; W511-L532 WeakPolarHBondContact CB-O 3.36Å; W511-L532 HydrophobicContact CE3-CB 4.48Å; W511-L532 HydrophobicContact CE3-CD2 4.36Å; W511-L532 PolarHBondContact O-N 3.33Å; M513-L532 HydrophobicContact CE-CB 4.11Å; W519-L532 HydrophobicContact CH2-CB 4.12Å; W519-L532 HydrophobicContact CH2-CD2 3.87Å; W519-L532 HydrophobicContact CZ3-CD2 4Å; L532-P534 WeakPolarHBondContact O-CD 3.37Å
533D98.4Very high96.4Very high0 Ų026.9 Ų26.90%014%0.14CC..  trans-64.5117.6171.4-173.5-18.1000110.3G326 Y354 Y361 R459 I535 K536G326-D533 WeakPolarHBondContact O-CB 3.47Å; G326-D533 PolarHBondContact O-N 3.4Å; Y354-D533 PolarHBondContact OH-OD2 2.9Å; Y361-D533 PolarHBondContact OH-OD1 2.85Å; Y361-D533 VanDerWaalsContact OH-OD1 3.1Å; R459-D533 PolarHBondContact NH2-O 3.46Å; D533-I535 PolarHBondContact O-N 3.07Å; D533-I535 VanDerWaalsContact O-N 3.13Å; D533-I535 WeakPolarHBondContact OD1-CG1 3.32Å; D533-I535 PolarHBondContact OD1-N 3.02Å; D533-K536 HydrophobicContact CB-CB 4.04Å; D533-K536 HydrophobicContact CB-CG 3.66Å; D533-K536 PolarHBondContact O-N 2.81Å; D533-K536 VanDerWaalsContact O-N 3.16Å; D533-K536 WeakPolarHBondContact OD2-CG 3.42Å; D533-K536 IonicContact OD2-NZ 2.81Å; D533-K536 PolarHBondContact OD2-NZ 3.13Å
534P98Very high96.6Very high0 Ų019.6 Ų19.60%011%0.109CC..THydrogen-bonded Turntrans-55.1-34.8-178.5-24.533.1000113I360 I452 A455 V456 R459 W511 L532 K536I360-P534 HydrophobicContact CD1-CG 4.11Å; I452-P534 HydrophobicContact CG2-CB 4.22Å; I452-P534 HydrophobicContact CG2-CG 4.49Å; A455-P534 WeakPolarHBondContact CB-O 3.48Å; V456-P534 HydrophobicContact CG2-CB 4.48Å; R459-P534 PolarHBondContact NE-O 3.23Å; R459-P534 PolarHBondContact NH2-O 3.19Å; R459-P534 VanDerWaalsContact NH2-O 3.11Å; W511-P534 HydrophobicContact CD2-CB 4.34Å; W511-P534 HydrophobicContact CD2-CG 3.81Å; W511-P534 HydrophobicContact CE3-CG 4.39Å; W511-P534 HydrophobicContact CG-CG 4.04Å; W511-P534 HydrophobicContact CH2-CB 4.19Å; W511-P534 HydrophobicContact CZ2-CB 3.94Å; W511-P534 HydrophobicContact CZ2-CG 4.12Å; L532-P534 WeakPolarHBondContact O-CD 3.37Å; P534-K536 VanDerWaalsContact C-N 3.32Å; P534-K536 PolarHBondContact O-N 3.18Å
535I97.4Very high96.7Very high8 Ų812.9 Ų12.94%0.0418%0.076CC..THydrogen-bonded Turntrans-83.1-9.5-172.787.4-177.3000113.3Y354 V451 I452 A455 D533 V537 F583Y354-I535 HydrophobicContact CD1-CD1 4.47Å; Y354-I535 HydrophobicContact CD2-CD1 4.3Å; Y354-I535 HydrophobicContact CE1-CD1 3.85Å; Y354-I535 HydrophobicContact CE2-CD1 3.6Å; Y354-I535 HydrophobicContact CE2-CG1 4.49Å; Y354-I535 WeakPolarHBondContact OH-CD1 3.45Å; V451-I535 HydrophobicContact CG1-CB 4.02Å; V451-I535 HydrophobicContact CG1-CD1 4.28Å; V451-I535 HydrophobicContact CG1-CG2 3.81Å; I452-I535 HydrophobicContact CG1-CG2 3.74Å; A455-I535 HydrophobicContact CB-CB 4.4Å; A455-I535 HydrophobicContact CB-CG2 4.45Å; D533-I535 PolarHBondContact O-N 3.07Å; D533-I535 VanDerWaalsContact O-N 3.13Å; D533-I535 WeakPolarHBondContact OD1-CG1 3.32Å; D533-I535 PolarHBondContact OD1-N 3.02Å; I535-V537 PolarHBondContact O-N 3.28Å; I535-F583 HydrophobicContact CB-CB 4.14Å; I535-F583 WeakPolarHBondContact CD1-O 3.49Å; I535-F583 WeakPolarHBondContact CG1-O 3.4Å; I535-F583 PolarHBondContact O-N 3.29Å
536K97.2Very high96.5Very high0 Ų018.2 Ų18.20%010%0.101CC..EExtended strand (participates in β ladder)trans-96.279.5177.9-60.7-69.5173.447.60109.1C322 W351 Y354 R459 D533 P534 M580 L582C322-K536 PolarHBondContact SG-NZ 2.97Å; C322-K536 VanDerWaalsContact SG-NZ 3.4Å; W351-K536 PolarHBondContact O-NZ 2.82Å; Y354-K536 WeakPolarHBondContact OH-CE 3.28Å; Y354-K536 PolarHBondContact OH-NZ 3.1Å; R459-K536 PolarHBondContact NH2-O 2.82Å; D533-K536 HydrophobicContact CB-CB 4.04Å; D533-K536 HydrophobicContact CB-CG 3.66Å; D533-K536 PolarHBondContact O-N 2.81Å; D533-K536 VanDerWaalsContact O-N 3.16Å; D533-K536 WeakPolarHBondContact OD2-CG 3.42Å; D533-K536 IonicContact OD2-NZ 2.81Å; D533-K536 PolarHBondContact OD2-NZ 3.13Å; P534-K536 VanDerWaalsContact C-N 3.32Å; P534-K536 PolarHBondContact O-N 3.18Å; K536-M580 HydrophobicContact CB-CE 3.76Å; K536-M580 HydrophobicContact CD-CE 3.77Å; K536-M580 HydrophobicContact CG-CE 4.27Å; K536-L582 HydrophobicContact CD-CD2 3.3Å
537V97.1Very high96.3Very high0 Ų022.4 Ų22.40%012%0.121CC..EExtended strand (participates in β ladder)trans-88.2118.8-167.8-1690000111.4A455 F458 R459 I535 M580 F581 F583A455-V537 HydrophobicContact CB-CG2 4.07Å; F458-V537 HydrophobicContact CD1-CB 4.36Å; F458-V537 HydrophobicContact CD1-CG1 3.73Å; F458-V537 HydrophobicContact CD1-CG2 4.42Å; F458-V537 HydrophobicContact CE1-CB 4.35Å; F458-V537 HydrophobicContact CE1-CG1 3.6Å; R459-V537 HydrophobicContact CG-CG1 3.78Å; R459-V537 HydrophobicContact CG-CG2 4.26Å; I535-V537 PolarHBondContact O-N 3.28Å; V537-M580 CarbonylContact O-C 3.28Å; V537-M580 WeakPolarHBondContact O-CA 3.33Å; V537-F581 PolarHBondContact N-O 3.21Å; V537-F581 PolarHBondContact O-N 2.85Å; V537-F583 HydrophobicContact CB-CD2 4.12Å; V537-F583 HydrophobicContact CB-CE2 3.92Å; V537-F583 HydrophobicContact CG2-CD2 3.49Å; V537-F583 VanDerWaalsContact CG2-CD2 3.49Å; V537-F583 HydrophobicContact CG2-CE2 3.56Å; V537-F583 HydrophobicContact CG2-CG 4.36Å; V537-F583 HydrophobicContact CG2-CZ 4.46Å
538S97.8Very high96Very high0 Ų019.1 Ų19.10%011%0.109CC..EExtended strand (participates in β ladder)trans-106.2135.7169.7-63.40000110W480 Q578 I579W480-S538 PolarHBondContact N-O 3.03Å; S538-Q578 PolarHBondContact OG-NE2 3.26Å; S538-I579 WeakPolarHBondContact CA-O 3.45Å
539I97.9Very high96Very high0 Ų022.6 Ų22.60%012%0.123CC..EExtended strand (participates in β ladder)trans-109.9148.8165.466.3175.2000109.4F458 M462 F477 K478 Q578 I579 F581 L599F458-I539 HydrophobicContact CE1-CG2 4.22Å; F458-I539 HydrophobicContact CZ-CG2 4.25Å; M462-I539 HydrophobicContact CE-CG2 4.33Å; M462-I539 HydrophobicContact CG-CG2 4.44Å; F477-I539 HydrophobicContact CB-CB 4.42Å; F477-I539 HydrophobicContact CB-CD1 4.26Å; F477-I539 HydrophobicContact CD1-CD1 4.37Å; F477-I539 HydrophobicContact CG-CD1 4.24Å; K478-I539 CarbonylContact O-C 3.48Å; K478-I539 WeakPolarHBondContact O-CA 3.37Å; I539-Q578 WeakPolarHBondContact O-CA 3.21Å; I539-I579 HydrophobicContact CD1-CB 4.43Å; I539-I579 HydrophobicContact CD1-CD1 4.38Å; I539-I579 HydrophobicContact CG1-CB 3.9Å; I539-I579 HydrophobicContact CG1-CD1 4.48Å; I539-I579 PolarHBondContact N-O 3.36Å; I539-I579 PolarHBondContact O-N 3.02Å; I539-F581 HydrophobicContact CD1-CE2 3.86Å; I539-F581 HydrophobicContact CG1-CE2 4.03Å; I539-L599 HydrophobicContact CD1-CD1 3.71Å; I539-L599 HydrophobicContact CD1-CD2 3.91Å; I539-L599 HydrophobicContact CD1-CG 4.5Å
540L98Very high95.9Very high10 Ų1023.9 Ų23.95%0.05213%0.13CC..EExtended strand (participates in β ladder)trans-112.1124.6-178.7-54.8177.3000109.1Y280 F477 K478 W480 F577 Q578Y280-L540 HydrophobicContact CD1-CD2 4.15Å; Y280-L540 HydrophobicContact CD2-CD2 4.19Å; Y280-L540 HydrophobicContact CE1-CD1 4.29Å; Y280-L540 HydrophobicContact CE1-CD2 4.17Å; Y280-L540 HydrophobicContact CE2-CD1 3.83Å; Y280-L540 HydrophobicContact CE2-CD2 4.22Å; Y280-L540 HydrophobicContact CG-CD2 4.15Å; F477-L540 CarbonylContact C-O 3.38Å; F477-L540 VanDerWaalsContact CA-O 3.31Å; F477-L540 WeakPolarHBondContact CA-O 3.49Å; K478-L540 HydrophobicContact CB-CB 4.45Å; K478-L540 PolarHBondContact N-O 3.18Å; K478-L540 PolarHBondContact O-N 2.95Å; W480-L540 HydrophobicContact CB-CD1 4.18Å; W480-L540 HydrophobicContact CB-CD2 4.21Å; W480-L540 HydrophobicContact CB-CG 4.05Å; W480-L540 HydrophobicContact CG-CD1 4.41Å; W480-L540 HydrophobicContact CG-CD2 4.49Å; L540-F577 CarbonylContact C-O 3.58Å; L540-F577 WeakPolarHBondContact CA-O 3.45Å; L540-Q578 HydrophobicContact CD2-CB 3.98Å; L540-Q578 HydrophobicContact CD2-CG 4.21Å
541A97.9Very high95.8Very high6 Ų628 Ų285%0.0515%0.15CC..  trans-78.8150.4166.700000110.2F477 V555 F577F477-A541 HydrophobicContact CD1-CB 4.03Å; F477-A541 HydrophobicContact CE1-CB 3.94Å; A541-V555 HydrophobicContact CB-CB 4.33Å; A541-V555 WeakPolarHBondContact CB-O 3.2Å; A541-F577 PolarHBondContact N-O 2.88Å
542P97.4Very high95.6Very high31 Ų3136.6 Ų36.620%0.20119%0.19CC..SBendtrans-63.5154.5175.129.1-37.9000111.5W475 G554 V555 F577W475-P542 HydrophobicContact CB-CG 4.36Å; W475-P542 HydrophobicContact CD2-CG 4.13Å; W475-P542 HydrophobicContact CE3-CG 3.58Å; W475-P542 HydrophobicContact CG-CG 4.48Å; W475-P542 HydrophobicContact CZ3-CG 4.21Å; P542-G554 CarbonylContact O-C 3.52Å; P542-G554 VanDerWaalsContact O-CA 3.27Å; P542-G554 WeakPolarHBondContact O-CA 3.34Å; P542-V555 HydrophobicContact CG-CB 3.93Å; P542-V555 HydrophobicContact CG-CG2 3.7Å; P542-V555 PolarHBondContact O-N 3.37Å; P542-F577 WeakPolarHBondContact O-CD1 3.5Å
543G96.3Very high95.4Very high0 Ų041.4 Ų41.40%022%0.219CC..SBendtrans132-6.3178.700000115.6L550 E551G543-L550 WeakPolarHBondContact O-CA 3.32Å; G543-L550 WeakPolarHBondContact O-CD2 3.46Å; G543-E551 WeakPolarHBondContact CA-OE2 3.32Å; G543-E551 PolarHBondContact N-OE2 3.03Å; G543-E551 PolarHBondContact O-N 2.9Å
544M95.4Very high95.4Very high15 Ų1541.6 Ų41.67%0.07422%0.221CC..BIsolated β-bridgetrans-135.2119.5-178.2178697400110.7R279 Y280 L550 F577R279-M544 HydrophobicContact CB-SD 4.46Å; R279-M544 HydrophobicContact CG-CG 4.24Å; Y280-M544 HydrophobicContact CD1-CB 4.3Å; Y280-M544 HydrophobicContact CD1-CG 4.01Å; Y280-M544 HydrophobicContact CE1-CB 3.76Å; Y280-M544 HydrophobicContact CE1-CG 3.64Å; M544-L550 HydrophobicContact CE-CD2 3.62Å; M544-L550 HydrophobicContact CE-CG 4.45Å; M544-L550 HydrophobicContact SD-CD2 4.35Å; M544-F577 HydrophobicContact CB-CD2 3.92Å; M544-F577 HydrophobicContact CB-CE2 4.35Å; M544-F577 HydrophobicContact CB-CG 4.29Å; M544-F577 HydrophobicContact CE-CD2 4.13Å; M544-F577 HydrophobicContact CE-CE2 4.1Å
545G93.3Very high95.4Very high13 Ų1341.8 Ų41.813%0.13422%0.222CC..  trans-74.4171.2-179.400000113.8R279 D547 G548 E549R279-G545 WeakPolarHBondContact CD-O 3.36Å; R279-G545 PolarHBondContact NE-O 3.2Å; G545-D547 PolarHBondContact O-N 3Å; G545-G548 PolarHBondContact O-N 2.86Å; G545-E549 PolarHBondContact N-O 2.83Å
546E90.1Very high95.4Very high116 Ų11641.4 Ų41.454%0.54222%0.221SC..THydrogen-bonded Turntrans-66.1-28.3177.1-67.9-158.8154.800113.8R279 G548R279-E546 PolarHBondContact NH1-O 3.43Å; E546-G548 PolarHBondContact O-N 2.99Å
547D90.3Very high95.4Very high128 Ų12841.4 Ų41.468%0.68422%0.221SC*.THydrogen-bonded Turntrans-72.3-14.5175.455.53.7000113.5G545 E549G545-D547 PolarHBondContact O-N 3Å; D547-E549 PolarHBondContact OD1-N 3.36Å
548G89.8Confident95.3Very high22 Ų2242.8 Ų42.823%0.22723%0.232CC..SBendtrans88.37.7-174.800000114.1G545 E546G545-G548 PolarHBondContact O-N 2.86Å; E546-G548 PolarHBondContact O-N 2.99Å
549E93.1Very high95.3Very high123 Ų12342.8 Ų42.858%0.57523%0.232SC*.  trans-88.7148.6172.9-62.9-60.9149.300110.8G545 D547G545-E549 PolarHBondContact N-O 2.83Å; D547-E549 PolarHBondContact OD1-N 3.36Å
550L94.5Very high95.4Very high30 Ų3042.8 Ų42.816%0.15723%0.232CC..BIsolated β-bridgetrans-73.7133.8177.8-65.3171000110.6G543 M544 F577 L643 K644G543-L550 WeakPolarHBondContact O-CA 3.32Å; G543-L550 WeakPolarHBondContact O-CD2 3.46Å; M544-L550 HydrophobicContact CE-CD2 3.62Å; M544-L550 HydrophobicContact CE-CG 4.45Å; M544-L550 HydrophobicContact SD-CD2 4.35Å; L550-F577 HydrophobicContact CD2-CD2 4.45Å; L550-F577 HydrophobicContact CD2-CE2 3.34Å; L550-F577 HydrophobicContact CD2-CZ 3.64Å; L550-L643 WeakPolarHBondContact CD1-O 3.22Å; L550-K644 HydrophobicContact CB-CG 4.09Å; L550-K644 HydrophobicContact CD1-CB 4.39Å; L550-K644 HydrophobicContact CD1-CG 3.98Å
551E95.4Very high95.3Very high87 Ų8744 Ų4441%0.40724%0.239SC..  trans-69.1177-178.6-65-178140.800112.3G543 T553 F640 K644G543-E551 WeakPolarHBondContact CA-OE2 3.32Å; G543-E551 PolarHBondContact N-OE2 3.03Å; G543-E551 PolarHBondContact O-N 2.9Å; E551-T553 VanDerWaalsContact C-N 3.31Å; E551-F640 WeakPolarHBondContact O-CZ 3.4Å; E551-K644 PolarHBondContact O-NZ 2.89Å
552E93.8Very high95.2Very high179 Ų17945.2 Ų45.284%0.83625%0.25SC*.SBendtrans-65-37.7176.1-70-169.817000112.2K644E552-K644 PolarHBondContact O-NZ 3.35Å
553T95.1Very high95.2Very high102 Ų10244 Ų4463%0.62624%0.241SC*.SBendtrans-132.5154.2179.4580000109.9E551 F640E551-T553 VanDerWaalsContact C-N 3.31Å; T553-F640 VanDerWaalsContact C-CZ 3.44Å; T553-F640 VanDerWaalsContact CA-CE1 3.43Å
554G96.9Very high95.3Very high4 Ų444 Ų444%0.04124%0.241CC..  trans-165165.1177.900000112.8P542 F640P542-G554 CarbonylContact O-C 3.52Å; P542-G554 VanDerWaalsContact O-CA 3.27Å; P542-G554 WeakPolarHBondContact O-CA 3.34Å; G554-F640 VanDerWaalsContact N-CE1 3.33Å
555V98.2Very high95.3Very high4 Ų445.2 Ų45.22%0.02426%0.258CS..  trans-115.8106.1-179.2176.20000108W475 A541 P542 A557 V560 F602 Y606W475-V555 HydrophobicContact CD2-CG2 4.32Å; W475-V555 HydrophobicContact CE3-CG2 4.14Å; W475-V555 HydrophobicContact CH2-CG1 4.23Å; W475-V555 HydrophobicContact CH2-CG2 3.79Å; W475-V555 HydrophobicContact CZ2-CG2 3.99Å; W475-V555 HydrophobicContact CZ3-CB 4.4Å; W475-V555 HydrophobicContact CZ3-CG1 4.41Å; W475-V555 HydrophobicContact CZ3-CG2 3.87Å; A541-V555 HydrophobicContact CB-CB 4.33Å; A541-V555 WeakPolarHBondContact CB-O 3.2Å; P542-V555 HydrophobicContact CG-CB 3.93Å; P542-V555 HydrophobicContact CG-CG2 3.7Å; P542-V555 PolarHBondContact O-N 3.37Å; V555-A557 PolarHBondContact O-N 2.99Å; V555-V560 HydrophobicContact CG1-CG2 3.73Å; V555-F602 HydrophobicContact CG1-CE1 3.66Å; V555-F602 HydrophobicContact CG1-CZ 3.96Å; V555-Y606 HydrophobicContact CG2-CD1 4.35Å; V555-Y606 HydrophobicContact CG2-CE1 3.72Å
556P97.8Very high95.3Very high0 Ų049.7 Ų49.70%027%0.271CS..  trans-62128-178.8-26.136.9000111.9A558 L559 V560 M639 F640 L643P556-A558 VanDerWaalsContact C-N 3.26Å; P556-A558 PolarHBondContact O-N 3.32Å; P556-L559 WeakPolarHBondContact O-CB 3.38Å; P556-L559 PolarHBondContact O-N 2.85Å; P556-L559 VanDerWaalsContact O-N 3.14Å; P556-V560 PolarHBondContact O-N 2.97Å; P556-M639 HydrophobicContact CB-CB 4.1Å; P556-M639 HydrophobicContact CB-SD 4.34Å; P556-M639 HydrophobicContact CG-CB 3.59Å; P556-F640 HydrophobicContact CG-CB 4.09Å; P556-L643 HydrophobicContact CB-CD1 4.16Å; P556-L643 HydrophobicContact CG-CD1 4.17Å
557A97.1Very high95.4Very high0 Ų048.8 Ų48.80%027%0.266CS..Hα-helixtrans-66.5-27.4-17700000112.9V555 L559 V560 T561 T574 T575 D576 I579V555-A557 PolarHBondContact O-N 2.99Å; A557-L559 VanDerWaalsContact C-N 3.29Å; A557-L559 PolarHBondContact O-N 2.99Å; A557-V560 PolarHBondContact O-N 3.08Å; A557-T561 WeakPolarHBondContact O-CB 3.43Å; A557-T561 PolarHBondContact O-N 3.1Å; A557-T561 PolarHBondContact O-OG1 3.04Å; A557-T574 HydrophobicContact CB-CG2 3.74Å; A557-T575 WeakPolarHBondContact CB-O 3.17Å; A557-D576 WeakPolarHBondContact CB-O 3.45Å; A557-D576 PolarHBondContact N-O 2.81Å; A557-I579 HydrophobicContact CB-CD1 4.13Å; A557-I579 HydrophobicContact CB-CG1 3.65Å
558A96.1Very high95.6Very high29 Ų2945.8 Ų45.824%0.2427%0.265CS..Hα-helixtrans-57-40.6172.100000112.5P556 T561 A562 W728P556-A558 VanDerWaalsContact C-N 3.26Å; P556-A558 PolarHBondContact O-N 3.32Å; A558-T561 PolarHBondContact O-N 2.86Å; A558-A562 PolarHBondContact O-N 3.39Å; A558-W728 HydrophobicContact CB-CZ2 3.97Å
559L97.8Very high95.8Very high0 Ų046.1 Ų46.10%026%0.261CS..Hα-helixtrans-68.1-41.1177.5-178.658.2000111.7P556 A557 T561 A562 W563 F602 Y606 M616 I632 L635 M639 F735P556-L559 WeakPolarHBondContact O-CB 3.38Å; P556-L559 PolarHBondContact O-N 2.85Å; P556-L559 VanDerWaalsContact O-N 3.14Å; A557-L559 VanDerWaalsContact C-N 3.29Å; A557-L559 PolarHBondContact O-N 2.99Å; L559-T561 VanDerWaalsContact C-N 3.35Å; L559-A562 PolarHBondContact O-N 2.99Å; L559-W563 PolarHBondContact O-N 3.45Å; L559-F602 HydrophobicContact CD2-CZ 4.41Å; L559-F602 HydrophobicContact CG-CE2 4.18Å; L559-F602 HydrophobicContact CG-CZ 4.3Å; L559-Y606 HydrophobicContact CD2-CD2 4.45Å; L559-Y606 HydrophobicContact CD2-CE2 4.06Å; L559-M616 HydrophobicContact CD1-SD 4.08Å; L559-I632 HydrophobicContact CD1-CG1 4.28Å; L559-I632 HydrophobicContact CD2-CG1 4.06Å; L559-I632 HydrophobicContact CG-CG1 4.41Å; L559-L635 HydrophobicContact CD1-CD2 3.81Å; L559-L635 HydrophobicContact CD1-CG 4.37Å; L559-M639 HydrophobicContact CB-SD 4.05Å; L559-F735 HydrophobicContact CD1-CE1 4.27Å; L559-F735 HydrophobicContact CD1-CZ 4.16Å
560V98.1Very high95.9Very high0 Ų046.1 Ų46.10%027%0.27CS..Hα-helixtrans-64.7-41.5176.2-1740000110.4F477 V555 P556 A557 W563 L564 I579 L599 F602F477-V560 HydrophobicContact CE1-CG1 4.08Å; F477-V560 HydrophobicContact CE1-CG2 3.84Å; F477-V560 HydrophobicContact CZ-CG1 3.84Å; F477-V560 HydrophobicContact CZ-CG2 3.92Å; V555-V560 HydrophobicContact CG1-CG2 3.73Å; P556-V560 PolarHBondContact O-N 2.97Å; A557-V560 PolarHBondContact O-N 3.08Å; V560-W563 WeakPolarHBondContact O-CB 3.48Å; V560-W563 PolarHBondContact O-N 2.84Å; V560-L564 HydrophobicContact CG1-CD1 4.26Å; V560-L564 HydrophobicContact CG1-CG 4.47Å; V560-L564 VanDerWaalsContact O-CG 3.28Å; V560-L564 WeakPolarHBondContact O-CG 3.31Å; V560-L564 PolarHBondContact O-N 3.37Å; V560-I579 HydrophobicContact CB-CD1 3.52Å; V560-I579 HydrophobicContact CG1-CD1 3.4Å; V560-I579 VanDerWaalsContact CG1-CD1 3.4Å; V560-I579 HydrophobicContact CG2-CD1 4.24Å; V560-L599 HydrophobicContact CG1-CD2 4.04Å; V560-F602 HydrophobicContact CG2-CD1 4.32Å; V560-F602 HydrophobicContact CG2-CE1 3.76Å; V560-F602 HydrophobicContact CG2-CE2 4.24Å; V560-F602 HydrophobicContact CG2-CZ 3.7Å
561T97Very high95.8Very high34 Ų3445.5 Ų45.521%0.20927%0.267CS..Hα-helixtrans-63-41.9176.2-710000111.9A557 A558 L559 W563 L564 G565 P571 T574A557-T561 WeakPolarHBondContact O-CB 3.43Å; A557-T561 PolarHBondContact O-N 3.1Å; A557-T561 PolarHBondContact O-OG1 3.04Å; A558-T561 PolarHBondContact O-N 2.86Å; L559-T561 VanDerWaalsContact C-N 3.35Å; T561-W563 VanDerWaalsContact C-N 3.33Å; T561-W563 PolarHBondContact O-N 2.89Å; T561-L564 PolarHBondContact O-N 2.9Å; T561-G565 PolarHBondContact O-N 2.7Å; T561-P571 HydrophobicContact CG2-CG 4.07Å; T561-T574 WeakPolarHBondContact OG1-CG2 3.3Å; T561-T574 PolarHBondContact OG1-OG1 3.37Å
562A96.4Very high95.7Very high32 Ų3243 Ų4326%0.26426%0.258SS..Hα-helixtrans-62.4-40.5174.200000112.1A558 L559 G565 R566 M616 F735A558-A562 PolarHBondContact O-N 3.39Å; L559-A562 PolarHBondContact O-N 2.99Å; A562-G565 PolarHBondContact O-N 2.75Å; A562-R566 PolarHBondContact O-N 3.24Å; A562-M616 HydrophobicContact CB-CE 3.69Å; A562-F735 HydrophobicContact CB-CD1 4.31Å; A562-F735 HydrophobicContact CB-CE1 3.56Å; A562-F735 HydrophobicContact CB-CZ 4.33Å
563W97.3Very high95.6Very high6 Ų635 Ų352%0.02322%0.22CC..Hα-helixtrans-61.3-46.4173171.6-92.5000112.4L559 V560 T561 G565 R566 H567 T598 F602 H605 V615 I632L559-W563 PolarHBondContact O-N 3.45Å; V560-W563 WeakPolarHBondContact O-CB 3.48Å; V560-W563 PolarHBondContact O-N 2.84Å; T561-W563 VanDerWaalsContact C-N 3.33Å; T561-W563 PolarHBondContact O-N 2.89Å; W563-G565 VanDerWaalsContact C-N 3.33Å; W563-G565 PolarHBondContact O-N 3.34Å; W563-R566 WeakPolarHBondContact O-CB 3.47Å; W563-R566 PolarHBondContact O-N 3.37Å; W563-H567 AromaticContact CE2-CD2 3.84Å; W563-H567 AromaticContact CE2-NE2 3.72Å; W563-H567 AromaticContact CH2-NE2 3.91Å; W563-H567 AromaticContact CZ2-NE2 3.55Å; W563-H567 AromaticContact NE1-CD2 3.86Å; W563-H567 PolarHBondContact O-CD2 3.38Å; W563-H567 PolarHBondContact O-N 3.5Å; W563-T598 PolarHBondContact NE1-O 3.23Å; W563-T598 VanDerWaalsContact NE1-O 3.07Å; W563-F602 HydrophobicContact CB-CD2 3.64Å; W563-F602 HydrophobicContact CB-CE2 4.1Å; W563-F602 AromaticContact CD1-CD2 3.8Å; W563-F602 HydrophobicContact CD2-CB 4.33Å; W563-F602 AromaticContact CD2-CD2 3.89Å; W563-F602 HydrophobicContact CD2-CD2 3.89Å; W563-F602 HydrophobicContact CG-CB 4.13Å; W563-F602 AromaticContact CG-CD2 3.49Å; W563-F602 HydrophobicContact CG-CD2 3.49Å; W563-F602 VanDerWaalsContact CG-CD2 3.49Å; W563-F602 HydrophobicContact CG-CE2 4.39Å; W563-F602 HydrophobicContact CG-CG 4.26Å; W563-H605 HydrophobicContact CH2-CB 4.38Å; W563-H605 AromaticContact CH2-CD2 3.58Å; W563-V615 HydrophobicContact CH2-CG1 4.47Å; W563-V615 HydrophobicContact CZ3-CB 3.83Å; W563-V615 HydrophobicContact CZ3-CG1 3.96Å; W563-I632 HydrophobicContact CE3-CD1 4.21Å
564L97.1Very high95.6Very high0 Ų032.2 Ų32.20%020%0.203CC..Hα-helixtrans-60.6-43.2177.2-69.9171.5000111.5V560 T561 R566 H567 G568 I569 P571 I579 F581 L595 T598 L599V560-L564 HydrophobicContact CG1-CD1 4.26Å; V560-L564 HydrophobicContact CG1-CG 4.47Å; V560-L564 VanDerWaalsContact O-CG 3.28Å; V560-L564 WeakPolarHBondContact O-CG 3.31Å; V560-L564 PolarHBondContact O-N 3.37Å; T561-L564 PolarHBondContact O-N 2.9Å; L564-R566 VanDerWaalsContact C-N 3.29Å; L564-R566 PolarHBondContact O-N 2.97Å; L564-H567 CarbonylContact O-C 3.58Å; L564-H567 WeakPolarHBondContact O-CA 3.45Å; L564-H567 PolarHBondContact O-N 2.83Å; L564-G568 PolarHBondContact O-N 3.24Å; L564-I569 CarbonylContact C-O 3.54Å; L564-I569 HydrophobicContact CB-CB 4.1Å; L564-I569 HydrophobicContact CB-CG2 4.26Å; L564-I569 HydrophobicContact CD2-CB 4.34Å; L564-I569 HydrophobicContact CD2-CD1 4.17Å; L564-I569 HydrophobicContact CD2-CG2 4.2Å; L564-I569 PolarHBondContact O-N 3.46Å; L564-P571 HydrophobicContact CD1-CG 3.79Å; L564-I579 HydrophobicContact CD1-CG2 4.33Å; L564-F581 HydrophobicContact CD1-CE1 4.17Å; L564-F581 HydrophobicContact CD1-CZ 3.74Å; L564-L595 HydrophobicContact CD2-CD1 3.82Å; L564-T598 HydrophobicContact CD2-CG2 3.75Å; L564-L599 HydrophobicContact CD2-CD2 4.26Å
565G95.1Very high95.4Very high41 Ų4133 Ų3342%0.42321%0.207SC..Hα-helixtrans-57.9-39.717800000112.8T561 A562 W563 H567 G568 I569T561-G565 PolarHBondContact O-N 2.7Å; A562-G565 PolarHBondContact O-N 2.75Å; W563-G565 VanDerWaalsContact C-N 3.33Å; W563-G565 PolarHBondContact O-N 3.34Å; G565-H567 PolarHBondContact O-N 2.83Å; G565-G568 PolarHBondContact O-N 3.12Å; G565-I569 WeakPolarHBondContact CA-O 3.49Å; G565-I569 PolarHBondContact N-O 3.43Å
566R93.8Very high95.2Very high107 Ų10734.6 Ų34.640%0.40422%0.216SC..Hα-helixtrans-61.6-28.3174.5-178.8169.6174.568-3113.4A562 W563 L564 G568 V615 P617 E618A562-R566 PolarHBondContact O-N 3.24Å; W563-R566 WeakPolarHBondContact O-CB 3.47Å; W563-R566 PolarHBondContact O-N 3.37Å; L564-R566 VanDerWaalsContact C-N 3.29Å; L564-R566 PolarHBondContact O-N 2.97Å; R566-G568 VanDerWaalsContact C-N 3.33Å; R566-V615 WeakPolarHBondContact CD-O 3.43Å; R566-V615 PolarHBondContact NE-O 3.48Å; R566-P617 VanDerWaalsContact NH2-CD 3.28Å; R566-E618 IonicContact CZ-OE1 2.71Å; R566-E618 IonicContact CZ-OE2 3.9Å; R566-E618 IonicContact NH1-OE1 3.99Å; R566-E618 PolarHBondContact NH1-OE1 2.92Å; R566-E618 IonicContact NH1-OE2 3Å; R566-E618 PolarHBondContact NH1-OE2 3.28Å; R566-E618 IonicContact NH2-OE1 3.47Å
567H93.7Very high95.1Very high96 Ų9634.7 Ų34.744%0.44422%0.216SC..THydrogen-bonded Turntrans-92.912.3175.4-72.4-74.4000113.4W563 L564 G565 I569 T598W563-H567 AromaticContact CE2-CD2 3.84Å; W563-H567 AromaticContact CE2-NE2 3.72Å; W563-H567 AromaticContact CH2-NE2 3.91Å; W563-H567 AromaticContact CZ2-NE2 3.55Å; W563-H567 AromaticContact NE1-CD2 3.86Å; W563-H567 PolarHBondContact O-CD2 3.38Å; W563-H567 PolarHBondContact O-N 3.5Å; L564-H567 CarbonylContact O-C 3.58Å; L564-H567 WeakPolarHBondContact O-CA 3.45Å; L564-H567 PolarHBondContact O-N 2.83Å; G565-H567 PolarHBondContact O-N 2.83Å; H567-I569 VanDerWaalsContact C-N 3.25Å; H567-I569 PolarHBondContact O-N 2.75Å; H567-T598 HydrophobicContact CB-CG2 3.99Å
568G93.8Very high95.1Very high65 Ų6534.7 Ų34.767%0.6722%0.216SC*.THydrogen-bonded Turntrans71.818179.700000113.8L564 G565 R566L564-G568 PolarHBondContact O-N 3.24Å; G565-G568 PolarHBondContact O-N 3.12Å; R566-G568 VanDerWaalsContact C-N 3.33Å
569I94.6Very high95.2Very high29 Ų2933.3 Ų33.315%0.14921%0.205CC..  trans-102.3120.2176.4-60.1174.1000108.1L564 G565 H567 P571 F581 L595 T598L564-I569 CarbonylContact C-O 3.54Å; L564-I569 HydrophobicContact CB-CB 4.1Å; L564-I569 HydrophobicContact CB-CG2 4.26Å; L564-I569 HydrophobicContact CD2-CB 4.34Å; L564-I569 HydrophobicContact CD2-CD1 4.17Å; L564-I569 HydrophobicContact CD2-CG2 4.2Å; L564-I569 PolarHBondContact O-N 3.46Å; G565-I569 WeakPolarHBondContact CA-O 3.49Å; G565-I569 PolarHBondContact N-O 3.43Å; H567-I569 VanDerWaalsContact C-N 3.25Å; H567-I569 PolarHBondContact O-N 2.75Å; I569-P571 WeakPolarHBondContact O-CD 3.38Å; I569-F581 HydrophobicContact CG2-CE1 4.06Å; I569-L595 HydrophobicContact CD1-CD1 4.3Å; I569-L595 HydrophobicContact CG2-CD1 4.12Å; I569-T598 HydrophobicContact CD1-CG2 4.18Å
570V93.4Very high95.1Very high124 Ų12433.3 Ų33.375%0.75221%0.205SC*.  trans-110.4107.2-178.4-177.10000109.1
571P94Very high95Very high16 Ų1634 Ų3410%0.10421%0.208CC..  trans-61.9152.4166.6-2133.9000111.2T561 L564 I569 I579 M580 F581T561-P571 HydrophobicContact CG2-CG 4.07Å; L564-P571 HydrophobicContact CD1-CG 3.79Å; I569-P571 WeakPolarHBondContact O-CD 3.38Å; P571-I579 HydrophobicContact CB-CG2 3.61Å; P571-I579 HydrophobicContact CG-CG2 3.68Å; P571-M580 CarbonylContact C-O 3.57Å; P571-M580 WeakPolarHBondContact CA-O 3.43Å; P571-M580 WeakPolarHBondContact CB-O 3.4Å; P571-F581 HydrophobicContact CB-CE1 4.12Å; P571-F581 HydrophobicContact CG-CE1 3.94Å; P571-F581 HydrophobicContact CG-CZ 4.29Å
572T92.2Very high94.9Very high34 Ų3434.4 Ų34.421%0.20921%0.208CC..SBendtrans-80.6-32.2178.5-157.90000112.5Y324 M580 L582Y324-T572 HydrophobicContact CE1-CG2 3.86Å; Y324-T572 PolarHBondContact OH-O 3.48Å; Y324-T572 PolarHBondContact OH-OG1 3.03Å; T572-M580 HydrophobicContact CG2-CB 3.62Å; T572-M580 HydrophobicContact CG2-CE 4.19Å; T572-M580 HydrophobicContact CG2-CG 3.65Å; T572-M580 HydrophobicContact CG2-SD 3.49Å; T572-M580 WeakPolarHBondContact CG2-SD 3.28Å; T572-M580 PolarHBondContact N-O 2.88Å; T572-L582 HydrophobicContact CG2-CD1 4.23Å; T572-L582 HydrophobicContact CG2-CD2 3.95Å; T572-L582 HydrophobicContact CG2-CG 3.69Å; T572-L582 WeakPolarHBondContact OG1-CD1 3.46Å
573R93.1Very high94.8Very high11 Ų1133.4 Ų33.44%0.04220%0.198CC..EExtended strand (participates in β ladder)trans-154.6144.9-178.8176.5174.2-174.6-113.7-4.3109.8G281 Y324 D325 M580 P699G281-R573 PolarHBondContact O-NH2 2.76Å; Y324-R573 HydrophobicContact CD1-CB 4.35Å; Y324-R573 HydrophobicContact CE1-CB 3.64Å; Y324-R573 HydrophobicContact CE1-CG 4.39Å; D325-R573 IonicContact OD1-CZ 3.55Å; D325-R573 IonicContact OD1-NH1 3.72Å; D325-R573 PolarHBondContact OD1-NH1 3.3Å; D325-R573 IonicContact OD2-CZ 2.74Å; D325-R573 IonicContact OD2-NH1 3.52Å; D325-R573 PolarHBondContact OD2-NH1 3.31Å; R573-M580 HydrophobicContact CB-CB 4.06Å; R573-M580 HydrophobicContact CB-SD 4.45Å; R573-M580 PolarHBondContact O-N 3.22Å; R573-P699 HydrophobicContact CB-CG 4.27Å; R573-P699 HydrophobicContact CG-CG 4.29Å
574T94.4Very high94.6Very high44 Ų4434.9 Ų34.927%0.2721%0.209SC..EExtended strand (participates in β ladder)trans-131.8133.8175.2-54.90000108.2A557 T561 Q578A557-T574 HydrophobicContact CB-CG2 3.74Å; T561-T574 WeakPolarHBondContact OG1-CG2 3.3Å; T561-T574 PolarHBondContact OG1-OG1 3.37Å; T574-Q578 CarbonylContact C-O 3.56Å; T574-Q578 WeakPolarHBondContact CA-O 3.36Å
575T93Very high94.3Very high20 Ų2036.1 Ų36.112%0.12322%0.215CC..  trans-110.8-161.9163.974.80000109.4Y280 A557 F577 Q578Y280-T575 WeakPolarHBondContact O-CB 3.46Å; Y280-T575 WeakPolarHBondContact O-CG2 3.42Å; Y280-T575 PolarHBondContact O-OG1 2.66Å; A557-T575 WeakPolarHBondContact CB-O 3.17Å; T575-F577 VanDerWaalsContact C-N 3.27Å; T575-F577 PolarHBondContact O-N 3.16Å; T575-Q578 PolarHBondContact N-O 3.48Å; T575-Q578 WeakPolarHBondContact OG1-CB 3.23Å; T575-Q578 PolarHBondContact OG1-N 3.32Å
576D93.5Very high93.8Very high39 Ų3936.7 Ų36.721%0.20922%0.222CC..SBendtrans-58.5-38.9177.9-60.7-20.6000112.5A557 L643 G649A557-D576 WeakPolarHBondContact CB-O 3.45Å; A557-D576 PolarHBondContact N-O 2.81Å; D576-L643 HydrophobicContact CB-CD2 4.45Å; D576-G649 VanDerWaalsContact OD2-CA 3.22Å; D576-G649 WeakPolarHBondContact OD2-CA 3.37Å; D576-G649 PolarHBondContact OD2-N 3.02Å
577F96.2Very high93.1Very high1 Ų133 Ų330%0.00421%0.21CC..SBendtrans-134.8-5.6-175.8-58.9-75.9000114.7Y280 L540 A541 P542 M544 L550 T575 F640 L643Y280-F577 HydrophobicContact CD1-CB 4.31Å; L540-F577 CarbonylContact C-O 3.58Å; L540-F577 WeakPolarHBondContact CA-O 3.45Å; A541-F577 PolarHBondContact N-O 2.88Å; P542-F577 WeakPolarHBondContact O-CD1 3.5Å; M544-F577 HydrophobicContact CB-CD2 3.92Å; M544-F577 HydrophobicContact CB-CE2 4.35Å; M544-F577 HydrophobicContact CB-CG 4.29Å; M544-F577 HydrophobicContact CE-CD2 4.13Å; M544-F577 HydrophobicContact CE-CE2 4.1Å; L550-F577 HydrophobicContact CD2-CD2 4.45Å; L550-F577 HydrophobicContact CD2-CE2 3.34Å; L550-F577 HydrophobicContact CD2-CZ 3.64Å; T575-F577 VanDerWaalsContact C-N 3.27Å; T575-F577 PolarHBondContact O-N 3.16Å; F577-F640 AromaticContact CE1-CD2 3.96Å; F577-F640 HydrophobicContact CE1-CD2 3.96Å; F577-F640 AromaticContact CE1-CE2 3.82Å; F577-F640 HydrophobicContact CE1-CE2 3.82Å; F577-F640 AromaticContact CZ-CD2 3.92Å; F577-F640 HydrophobicContact CZ-CD2 3.92Å; F577-F640 AromaticContact CZ-CE2 3.64Å; F577-F640 HydrophobicContact CZ-CE2 3.64Å; F577-L643 HydrophobicContact CE1-CD1 4.35Å; F577-L643 HydrophobicContact CE2-CD1 4.44Å; F577-L643 HydrophobicContact CZ-CD1 3.82Å
578Q96.6Very high92.2Very high0 Ų032.9 Ų32.90%022%0.217CC..EExtended strand (participates in β ladder)trans-102.8138.5177176.7-96.66.500111I282 S538 I539 L540 T574 T575 M580I282-Q578 HydrophobicContact CD1-CG 4.14Å; I282-Q578 HydrophobicContact CG1-CG 4.29Å; S538-Q578 PolarHBondContact OG-NE2 3.26Å; I539-Q578 WeakPolarHBondContact O-CA 3.21Å; L540-Q578 HydrophobicContact CD2-CB 3.98Å; L540-Q578 HydrophobicContact CD2-CG 4.21Å; T574-Q578 CarbonylContact C-O 3.56Å; T574-Q578 WeakPolarHBondContact CA-O 3.36Å; T575-Q578 PolarHBondContact N-O 3.48Å; T575-Q578 WeakPolarHBondContact OG1-CB 3.23Å; T575-Q578 PolarHBondContact OG1-N 3.32Å; Q578-M580 VanDerWaalsContact NE2-CB 3.33Å
579I97.6Very high91.3Very high0 Ų036 Ų360%021%0.208CC..EExtended strand (participates in β ladder)trans-126.5123.7172.6-52166.5000107.8S538 I539 A557 V560 L564 P571 F581S538-I579 WeakPolarHBondContact CA-O 3.45Å; I539-I579 HydrophobicContact CD1-CB 4.43Å; I539-I579 HydrophobicContact CD1-CD1 4.38Å; I539-I579 HydrophobicContact CG1-CB 3.9Å; I539-I579 HydrophobicContact CG1-CD1 4.48Å; I539-I579 PolarHBondContact N-O 3.36Å; I539-I579 PolarHBondContact O-N 3.02Å; A557-I579 HydrophobicContact CB-CD1 4.13Å; A557-I579 HydrophobicContact CB-CG1 3.65Å; V560-I579 HydrophobicContact CB-CD1 3.52Å; V560-I579 HydrophobicContact CG1-CD1 3.4Å; V560-I579 VanDerWaalsContact CG1-CD1 3.4Å; V560-I579 HydrophobicContact CG2-CD1 4.24Å; L564-I579 HydrophobicContact CD1-CG2 4.33Å; P571-I579 HydrophobicContact CB-CG2 3.61Å; P571-I579 HydrophobicContact CG-CG2 3.68Å; I579-F581 HydrophobicContact CB-CE2 4.43Å; I579-F581 HydrophobicContact CG2-CE1 4.43Å; I579-F581 HydrophobicContact CG2-CE2 3.81Å; I579-F581 HydrophobicContact CG2-CZ 3.66Å
580M96.9Very high90.3Very high0 Ų036.4 Ų36.40%022%0.22CC..EExtended strand (participates in β ladder)trans-106.7138.6-174.5-158.4-171.3164.500112.5Y324 K536 V537 P571 T572 R573 Q578 L582Y324-M580 HydrophobicContact CD1-SD 3.86Å; Y324-M580 HydrophobicContact CE1-SD 3.84Å; Y324-M580 WeakPolarHBondContact O-CE 3.48Å; K536-M580 HydrophobicContact CB-CE 3.76Å; K536-M580 HydrophobicContact CD-CE 3.77Å; K536-M580 HydrophobicContact CG-CE 4.27Å; V537-M580 CarbonylContact O-C 3.28Å; V537-M580 WeakPolarHBondContact O-CA 3.33Å; P571-M580 CarbonylContact C-O 3.57Å; P571-M580 WeakPolarHBondContact CA-O 3.43Å; P571-M580 WeakPolarHBondContact CB-O 3.4Å; T572-M580 HydrophobicContact CG2-CB 3.62Å; T572-M580 HydrophobicContact CG2-CE 4.19Å; T572-M580 HydrophobicContact CG2-CG 3.65Å; T572-M580 HydrophobicContact CG2-SD 3.49Å; T572-M580 WeakPolarHBondContact CG2-SD 3.28Å; T572-M580 PolarHBondContact N-O 2.88Å; R573-M580 HydrophobicContact CB-CB 4.06Å; R573-M580 HydrophobicContact CB-SD 4.45Å; R573-M580 PolarHBondContact O-N 3.22Å; Q578-M580 VanDerWaalsContact NE2-CB 3.33Å; M580-L582 HydrophobicContact CE-CD2 3.64Å
581F95.5Very high89.6Confident14 Ų1436.6 Ų36.66%0.06121%0.211CC..EExtended strand (participates in β ladder)trans-124.9139.2172.9-56.6-82.1000110.6V537 I539 L564 I569 P571 I579 F583 L595V537-F581 PolarHBondContact N-O 3.21Å; V537-F581 PolarHBondContact O-N 2.85Å; I539-F581 HydrophobicContact CD1-CE2 3.86Å; I539-F581 HydrophobicContact CG1-CE2 4.03Å; L564-F581 HydrophobicContact CD1-CE1 4.17Å; L564-F581 HydrophobicContact CD1-CZ 3.74Å; I569-F581 HydrophobicContact CG2-CE1 4.06Å; P571-F581 HydrophobicContact CB-CE1 4.12Å; P571-F581 HydrophobicContact CG-CE1 3.94Å; P571-F581 HydrophobicContact CG-CZ 4.29Å; I579-F581 HydrophobicContact CB-CE2 4.43Å; I579-F581 HydrophobicContact CG2-CE1 4.43Å; I579-F581 HydrophobicContact CG2-CE2 3.81Å; I579-F581 HydrophobicContact CG2-CZ 3.66Å; F581-F583 HydrophobicContact CB-CE2 4.17Å; F581-L595 HydrophobicContact CD1-CD2 3.97Å; F581-L595 HydrophobicContact CD2-CD2 4.03Å; F581-L595 HydrophobicContact CE1-CD1 3.83Å; F581-L595 HydrophobicContact CE1-CD2 3.94Å; F581-L595 HydrophobicContact CE2-CD1 4.34Å; F581-L595 HydrophobicContact CE2-CD2 4Å; F581-L595 HydrophobicContact CG-CD2 4.01Å; F581-L595 HydrophobicContact CZ-CD1 3.66Å; F581-L595 HydrophobicContact CZ-CD2 3.95Å; F581-L595 HydrophobicContact CZ-CG 4.44Å
582L94.2Very high89.4Confident43 Ų4338.7 Ų38.723%0.22522%0.217CC..EExtended strand (participates in β ladder)trans-98.1116.4172.6-58.7178.9000109W351 K536 T572 M580W351-L582 HydrophobicContact CE3-CD1 4.18Å; W351-L582 HydrophobicContact CH2-CD1 3.76Å; W351-L582 HydrophobicContact CZ3-CD1 3.4Å; W351-L582 VanDerWaalsContact CZ3-CD1 3.4Å; K536-L582 HydrophobicContact CD-CD2 3.3Å; T572-L582 HydrophobicContact CG2-CD1 4.23Å; T572-L582 HydrophobicContact CG2-CD2 3.95Å; T572-L582 HydrophobicContact CG2-CG 3.69Å; T572-L582 WeakPolarHBondContact OG1-CD1 3.46Å; M580-L582 HydrophobicContact CE-CD2 3.64Å
583F95.4Very high89.5Confident12 Ų1238.6 Ų38.65%0.05322%0.223CC..  trans-86.2110.4167.1-75.5-114.6000107.3V451 E454 A455 F458 I535 V537 F581 W592V451-F583 HydrophobicContact CG1-CB 3.95Å; V451-F583 WeakPolarHBondContact CG1-O 3.31Å; E454-F583 HydrophobicContact CB-CD1 4.37Å; A455-F583 HydrophobicContact CB-CB 4Å; A455-F583 HydrophobicContact CB-CD1 3.96Å; A455-F583 HydrophobicContact CB-CD2 4.39Å; A455-F583 HydrophobicContact CB-CG 3.86Å; F458-F583 HydrophobicContact CB-CE1 3.98Å; F458-F583 HydrophobicContact CB-CZ 3.67Å; F458-F583 AromaticContact CD1-CE2 3.8Å; F458-F583 HydrophobicContact CD1-CE2 3.8Å; F458-F583 AromaticContact CD1-CZ 3.5Å; F458-F583 HydrophobicContact CD1-CZ 3.5Å; F458-F583 VanDerWaalsContact CD1-CZ 3.5Å; F458-F583 HydrophobicContact CD2-CZ 4.4Å; F458-F583 HydrophobicContact CE1-CE2 4.26Å; F458-F583 HydrophobicContact CE1-CZ 4.23Å; F458-F583 HydrophobicContact CG-CE1 4.38Å; F458-F583 HydrophobicContact CG-CE2 4.36Å; F458-F583 AromaticContact CG-CZ 3.59Å; F458-F583 HydrophobicContact CG-CZ 3.59Å; I535-F583 HydrophobicContact CB-CB 4.14Å; I535-F583 WeakPolarHBondContact CD1-O 3.49Å; I535-F583 WeakPolarHBondContact CG1-O 3.4Å; I535-F583 PolarHBondContact O-N 3.29Å; V537-F583 HydrophobicContact CB-CD2 4.12Å; V537-F583 HydrophobicContact CB-CE2 3.92Å; V537-F583 HydrophobicContact CG2-CD2 3.49Å; V537-F583 VanDerWaalsContact CG2-CD2 3.49Å; V537-F583 HydrophobicContact CG2-CE2 3.56Å; V537-F583 HydrophobicContact CG2-CG 4.36Å; V537-F583 HydrophobicContact CG2-CZ 4.46Å; F581-F583 HydrophobicContact CB-CE2 4.17Å; F583-W592 HydrophobicContact CE1-CB 4.07Å; F583-W592 HydrophobicContact CZ-CB 4.13Å
584S93Very high89.5Confident36 Ų3642.3 Ų42.325%0.25225%0.247SC..  trans-109.9168.2179.972.60000111G586 V587S584-G586 PolarHBondContact O-N 3.48Å; S584-G586 PolarHBondContact OG-N 2.93Å; S584-V587 WeakPolarHBondContact O-CB 3.29Å; S584-V587 WeakPolarHBondContact O-CG2 3.42Å; S584-V587 PolarHBondContact O-N 2.87Å
585M90.5Very high89.5Confident26 Ų2640.9 Ų40.913%0.12824%0.237CC..THydrogen-bonded Turntrans-61.3-10.8174.2-71.4-174.2-79.900114.3L388 L389 M439 L447 V451L388-M585 WeakPolarHBondContact O-CE 3.09Å; L389-M585 VanDerWaalsContact CA-CE 3.48Å; L389-M585 HydrophobicContact CB-CE 4.17Å; L389-M585 HydrophobicContact CD2-CE 3.42Å; L389-M585 VanDerWaalsContact CD2-CE 3.42Å; L389-M585 HydrophobicContact CG-CE 4.37Å; M439-M585 HydrophobicContact CE-CE 3.72Å; M439-M585 HydrophobicContact CE-SD 3.38Å; M439-M585 WeakPolarHBondContact CE-SD 3.4Å; M439-M585 HydrophobicContact SD-CE 4.19Å; M439-M585 HydrophobicContact SD-SD 4.26Å; L447-M585 HydrophobicContact CB-CG 4.49Å; L447-M585 HydrophobicContact CB-SD 3.7Å; L447-M585 HydrophobicContact CD1-SD 4.31Å; L447-M585 HydrophobicContact CG-SD 4.49Å; V451-M585 HydrophobicContact CG2-CB 4.21Å; V451-M585 HydrophobicContact CG2-CG 3.7Å
586G85.5Confident89.7Confident54 Ų5440.9 Ų40.956%0.55724%0.237SC*.THydrogen-bonded Turntrans-87.2-2.2172.600000114.5S584 T588S584-G586 PolarHBondContact O-N 3.48Å; S584-G586 PolarHBondContact OG-N 2.93Å; G586-T588 PolarHBondContact O-N 2.74Å
587V78.5Confident89.8Confident28 Ų2844.5 Ų44.517%0.1726%0.257CS..PPolyproline II helixtrans-74.3125.2176.7175.50000109.4S584 K591S584-V587 WeakPolarHBondContact O-CB 3.29Å; S584-V587 WeakPolarHBondContact O-CG2 3.42Å; S584-V587 PolarHBondContact O-N 2.87Å; V587-K591 HydrophobicContact CG1-CB 4.12Å; V587-K591 HydrophobicContact CG1-CD 4.44Å
588T74.9Confident89.9Confident95 Ų9545 Ų4558%0.58326%0.26SS*.PPolyproline II helixtrans-77.7143.1173.3560000110.5G586 G590 K591G586-T588 PolarHBondContact O-N 2.74Å; T588-G590 PolarHBondContact O-N 3.4Å; T588-K591 VanDerWaalsContact O-CB 3.29Å; T588-K591 WeakPolarHBondContact O-CB 3.5Å; T588-K591 PolarHBondContact O-N 3.12Å
589R74.6Confident89.9Confident129 Ų12945 Ų4549%0.48726%0.26SS..THydrogen-bonded Turntrans-50.7127.1177.4-62.1-166.6-170.1152.86.7111.7S50 E450 E454 K591S50-R589 PolarHBondContact O-NH1 3.08Å; S50-R589 PolarHBondContact O-NH2 3.36Å; E450-R589 IonicContact OE2-CZ 3.01Å; E450-R589 VanDerWaalsContact OE2-CZ 3.26Å; E450-R589 IonicContact OE2-NE 3.78Å; E450-R589 PolarHBondContact OE2-NE 3.36Å; E450-R589 IonicContact OE2-NH2 2.77Å; E450-R589 PolarHBondContact OE2-NH2 2.98Å; E454-R589 VanDerWaalsContact OE1-CA 3.24Å; E454-R589 WeakPolarHBondContact OE1-CA 3.48Å; E454-R589 VanDerWaalsContact OE1-CB 3.25Å; E454-R589 WeakPolarHBondContact OE1-CB 3.46Å; E454-R589 VanDerWaalsContact OE1-CG 3.31Å; E454-R589 WeakPolarHBondContact OE1-CG 3.46Å; R589-K591 PolarHBondContact O-N 3.01Å
590G73.2Confident89.9Confident39 Ų3946.9 Ų46.940%0.40227%0.272SS..THydrogen-bonded Turntrans79.72.2179.100000116.5E454 T588 W592 G593E454-G590 PolarHBondContact OE2-N 2.88Å; T588-G590 PolarHBondContact O-N 3.4Å; G590-W592 PolarHBondContact O-N 3.12Å; G590-W592 VanDerWaalsContact O-N 3.16Å; G590-G593 PolarHBondContact O-N 2.99Å
591K79.4Confident90Very high127 Ų12748 Ų4855%0.55228%0.28SS*.Hα-helixtrans-55.9-32.2174.4-174.7177.7179.1-177.70112.2V587 T588 R589 G593 T594V587-K591 HydrophobicContact CG1-CB 4.12Å; V587-K591 HydrophobicContact CG1-CD 4.44Å; T588-K591 VanDerWaalsContact O-CB 3.29Å; T588-K591 WeakPolarHBondContact O-CB 3.5Å; T588-K591 PolarHBondContact O-N 3.12Å; R589-K591 PolarHBondContact O-N 3.01Å; K591-G593 PolarHBondContact O-N 3.38Å; K591-T594 WeakPolarHBondContact O-CB 3.29Å; K591-T594 PolarHBondContact O-N 3.03Å; K591-T594 VanDerWaalsContact O-N 3.13Å
592W89.7Confident90.1Very high61 Ų6147.4 Ų47.423%0.23128%0.278CS..Hα-helixtrans-62.1-22.7177.364-103.7000112.9E454 D457 F458 A461 F583 G590 T594 L595 V596E454-W592 PolarHBondContact OE2-NE1 3.36Å; E454-W592 VanDerWaalsContact OE2-NE1 3.11Å; D457-W592 HydrophobicContact CB-CZ2 4.18Å; F458-W592 HydrophobicContact CB-CB 3.89Å; F458-W592 HydrophobicContact CB-CD2 4.15Å; F458-W592 HydrophobicContact CB-CE3 4.47Å; F458-W592 HydrophobicContact CB-CG 3.89Å; F458-W592 HydrophobicContact CD2-CB 3.68Å; F458-W592 HydrophobicContact CD2-CD2 4.38Å; F458-W592 HydrophobicContact CD2-CE3 4.09Å; F458-W592 HydrophobicContact CD2-CG 4.27Å; F458-W592 HydrophobicContact CG-CB 4.02Å; F458-W592 HydrophobicContact CG-CG 4.49Å; A461-W592 HydrophobicContact CB-CE3 4.46Å; A461-W592 HydrophobicContact CB-CH2 4.11Å; A461-W592 HydrophobicContact CB-CZ3 3.71Å; F583-W592 HydrophobicContact CE1-CB 4.07Å; F583-W592 HydrophobicContact CZ-CB 4.13Å; G590-W592 PolarHBondContact O-N 3.12Å; G590-W592 VanDerWaalsContact O-N 3.16Å; W592-T594 VanDerWaalsContact C-N 3.28Å; W592-T594 PolarHBondContact O-N 3.39Å; W592-L595 WeakPolarHBondContact O-CA 3.49Å; W592-L595 WeakPolarHBondContact O-CB 3.44Å; W592-L595 PolarHBondContact O-N 3.13Å; W592-V596 HydrophobicContact CE3-CG2 3.79Å; W592-V596 HydrophobicContact CZ3-CG2 4.12Å; W592-V596 WeakPolarHBondContact O-CG2 3.34Å; W592-V596 PolarHBondContact O-N 3.46Å
593G92.9Very high90.3Very high32 Ų3245.6 Ų45.633%0.3327%0.268SS..Hα-helixtrans-60.4-36.7173.300000112.7G590 K591 N597G590-G593 PolarHBondContact O-N 2.99Å; K591-G593 PolarHBondContact O-N 3.38Å; G593-N597 WeakPolarHBondContact O-CB 3.41Å; G593-N597 PolarHBondContact O-N 3.27Å
594T93.5Very high90.4Very high89 Ų8951.5 Ų51.555%0.54629%0.29SS..Hα-helixtrans-66.5-37.8173.1-57.80000111.7K591 W592 T598K591-T594 WeakPolarHBondContact O-CB 3.29Å; K591-T594 PolarHBondContact O-N 3.03Å; K591-T594 VanDerWaalsContact O-N 3.13Å; W592-T594 VanDerWaalsContact C-N 3.28Å; W592-T594 PolarHBondContact O-N 3.39Å; T594-T598 WeakPolarHBondContact O-CB 3.17Å; T594-T598 PolarHBondContact O-N 2.8Å; T594-T598 PolarHBondContact O-OG1 2.83Å
595L95.8Very high90.7Very high14 Ų1451.2 Ų51.27%0.07328%0.284CS..Hα-helixtrans-65.1-49.7175.7172.758000110.7F458 L564 I569 F581 W592 N597 T598 L599F458-L595 HydrophobicContact CE1-CD2 4.28Å; F458-L595 HydrophobicContact CE2-CD2 3.69Å; F458-L595 HydrophobicContact CE2-CG 3.96Å; F458-L595 HydrophobicContact CZ-CD2 3.51Å; F458-L595 HydrophobicContact CZ-CG 4.1Å; L564-L595 HydrophobicContact CD2-CD1 3.82Å; I569-L595 HydrophobicContact CD1-CD1 4.3Å; I569-L595 HydrophobicContact CG2-CD1 4.12Å; F581-L595 HydrophobicContact CD1-CD2 3.97Å; F581-L595 HydrophobicContact CD2-CD2 4.03Å; F581-L595 HydrophobicContact CE1-CD1 3.83Å; F581-L595 HydrophobicContact CE1-CD2 3.94Å; F581-L595 HydrophobicContact CE2-CD1 4.34Å; F581-L595 HydrophobicContact CE2-CD2 4Å; F581-L595 HydrophobicContact CG-CD2 4.01Å; F581-L595 HydrophobicContact CZ-CD1 3.66Å; F581-L595 HydrophobicContact CZ-CD2 3.95Å; F581-L595 HydrophobicContact CZ-CG 4.44Å; W592-L595 WeakPolarHBondContact O-CA 3.49Å; W592-L595 WeakPolarHBondContact O-CB 3.44Å; W592-L595 PolarHBondContact O-N 3.13Å; L595-N597 VanDerWaalsContact C-N 3.34Å; L595-N597 PolarHBondContact O-N 2.55Å; L595-T598 PolarHBondContact O-N 3.14Å; L595-T598 VanDerWaalsContact O-N 3.16Å; L595-L599 HydrophobicContact CD1-CD1 4.18Å; L595-L599 HydrophobicContact CD1-CG 4.21Å; L595-L599 HydrophobicContact CG-CD1 4.26Å; L595-L599 WeakPolarHBondContact O-CG 3.44Å; L595-L599 PolarHBondContact O-N 3.43Å
596V96.3Very high91.1Very high19 Ų1950.1 Ų50.112%0.11528%0.279CS..Hα-helixtrans-57-47.2176.4173.80000111F458 M462 L465 W592 T598 L599 C600F458-V596 HydrophobicContact CD2-CG2 3.77Å; F458-V596 HydrophobicContact CE2-CG2 3.63Å; M462-V596 HydrophobicContact SD-CG2 4.02Å; L465-V596 HydrophobicContact CD1-CG1 3.47Å; L465-V596 VanDerWaalsContact CD1-CG1 3.47Å; W592-V596 HydrophobicContact CE3-CG2 3.79Å; W592-V596 HydrophobicContact CZ3-CG2 4.12Å; W592-V596 WeakPolarHBondContact O-CG2 3.34Å; W592-V596 PolarHBondContact O-N 3.46Å; V596-T598 VanDerWaalsContact C-N 3.33Å; V596-T598 PolarHBondContact O-N 3Å; V596-L599 PolarHBondContact O-N 2.73Å; V596-C600 PolarHBondContact O-N 3.5Å; V596-C600 PolarHBondContact O-SG 2.84Å; V596-C600 VanDerWaalsContact O-SG 3.41Å
597N95.9Very high91.7Very high116 Ų11651.5 Ų51.562%0.6227%0.274SS*.Hα-helixtrans-61.6-40.3178.1-171.824.8000112.2G593 L595 L599 C600 S601G593-N597 WeakPolarHBondContact O-CB 3.41Å; G593-N597 PolarHBondContact O-N 3.27Å; L595-N597 VanDerWaalsContact C-N 3.34Å; L595-N597 PolarHBondContact O-N 2.55Å; N597-L599 VanDerWaalsContact C-N 3.34Å; N597-L599 PolarHBondContact O-N 3.44Å; N597-C600 PolarHBondContact O-N 3.28Å; N597-S601 WeakPolarHBondContact O-CB 3.47Å; N597-S601 PolarHBondContact O-N 2.84Å
598T97.3Very high92.6Very high12 Ų1253.5 Ų53.57%0.07429%0.293CS..Hα-helixtrans-64.6-37.9176.9-54.30000111.9W563 L564 H567 I569 T594 L595 V596 S601 F602W563-T598 PolarHBondContact NE1-O 3.23Å; W563-T598 VanDerWaalsContact NE1-O 3.07Å; L564-T598 HydrophobicContact CD2-CG2 3.75Å; H567-T598 HydrophobicContact CB-CG2 3.99Å; I569-T598 HydrophobicContact CD1-CG2 4.18Å; T594-T598 WeakPolarHBondContact O-CB 3.17Å; T594-T598 PolarHBondContact O-N 2.8Å; T594-T598 PolarHBondContact O-OG1 2.83Å; L595-T598 PolarHBondContact O-N 3.14Å; L595-T598 VanDerWaalsContact O-N 3.16Å; V596-T598 VanDerWaalsContact C-N 3.33Å; V596-T598 PolarHBondContact O-N 3Å; T598-S601 PolarHBondContact O-N 2.95Å; T598-F602 PolarHBondContact O-N 2.98Å
599L98Very high93.7Very high0 Ų051.5 Ų51.50%028%0.279CS..Hα-helixtrans-67.8-42.4174.4-67.1170.5000112.1M462 F476 F477 I539 V560 L564 L595 V596 N597 S601 F602 K603M462-L599 HydrophobicContact CE-CD1 3.89Å; M462-L599 HydrophobicContact SD-CD1 4Å; F476-L599 HydrophobicContact CZ-CB 4.44Å; F477-L599 HydrophobicContact CD2-CB 4.04Å; F477-L599 HydrophobicContact CD2-CD1 4.43Å; F477-L599 HydrophobicContact CD2-CD2 3.97Å; F477-L599 HydrophobicContact CD2-CG 4.36Å; F477-L599 HydrophobicContact CE2-CB 3.98Å; F477-L599 HydrophobicContact CE2-CD2 3.71Å; F477-L599 HydrophobicContact CE2-CG 4.37Å; F477-L599 HydrophobicContact CZ-CD2 4.14Å; I539-L599 HydrophobicContact CD1-CD1 3.71Å; I539-L599 HydrophobicContact CD1-CD2 3.91Å; I539-L599 HydrophobicContact CD1-CG 4.5Å; V560-L599 HydrophobicContact CG1-CD2 4.04Å; L564-L599 HydrophobicContact CD2-CD2 4.26Å; L595-L599 HydrophobicContact CD1-CD1 4.18Å; L595-L599 HydrophobicContact CD1-CG 4.21Å; L595-L599 HydrophobicContact CG-CD1 4.26Å; L595-L599 WeakPolarHBondContact O-CG 3.44Å; L595-L599 PolarHBondContact O-N 3.43Å; V596-L599 PolarHBondContact O-N 2.73Å; N597-L599 VanDerWaalsContact C-N 3.34Å; N597-L599 PolarHBondContact O-N 3.44Å; L599-S601 VanDerWaalsContact C-N 3.3Å; L599-S601 PolarHBondContact O-N 2.98Å; L599-F602 WeakPolarHBondContact O-CB 3.24Å; L599-F602 PolarHBondContact O-N 2.82Å; L599-K603 PolarHBondContact O-N 2.85Å
600C97.7Very high94.9Very high39 Ų3946 Ų4626%0.26426%0.259SS..Hα-helixtrans-61.8-39.3172.4-69.30000111.7V596 N597 K603 R604V596-C600 PolarHBondContact O-N 3.5Å; V596-C600 PolarHBondContact O-SG 2.84Å; V596-C600 VanDerWaalsContact O-SG 3.41Å; N597-C600 PolarHBondContact O-N 3.28Å; C600-K603 PolarHBondContact O-N 2.96Å; C600-R604 WeakPolarHBondContact O-CB 3.26Å; C600-R604 PolarHBondContact O-N 2.8Å
601S97.7Very high96.1Very high24 Ų2447.7 Ų47.717%0.16826%0.263CS..Hα-helixtrans-66.4-41.7176-166.30000112.1N597 T598 L599 R604 H605N597-S601 WeakPolarHBondContact O-CB 3.47Å; N597-S601 PolarHBondContact O-N 2.84Å; T598-S601 PolarHBondContact O-N 2.95Å; L599-S601 VanDerWaalsContact C-N 3.3Å; L599-S601 PolarHBondContact O-N 2.98Å; S601-R604 PolarHBondContact O-N 2.99Å; S601-R604 PolarHBondContact OG-NH2 3.35Å; S601-H605 PolarHBondContact O-CD2 2.65Å; S601-H605 VanDerWaalsContact O-CD2 3.31Å; S601-H605 PolarHBondContact O-N 3.34Å
602F98.5Very high96.9Very high0 Ų041.6 Ų41.60%024%0.237CC..Hα-helixtrans-54-56.5172.1176.4-96.2000110W475 F477 V555 L559 V560 W563 T598 L599 R604 H605 Y606 I632W475-F602 HydrophobicContact CH2-CD1 4.09Å; W475-F602 AromaticContact CH2-CE1 3.93Å; W475-F602 HydrophobicContact CH2-CE1 3.93Å; F477-F602 HydrophobicContact CE2-CD1 4.3Å; F477-F602 AromaticContact CZ-CD1 3.81Å; F477-F602 HydrophobicContact CZ-CD1 3.81Å; F477-F602 HydrophobicContact CZ-CE1 4.16Å; V555-F602 HydrophobicContact CG1-CE1 3.66Å; V555-F602 HydrophobicContact CG1-CZ 3.96Å; L559-F602 HydrophobicContact CD2-CZ 4.41Å; L559-F602 HydrophobicContact CG-CE2 4.18Å; L559-F602 HydrophobicContact CG-CZ 4.3Å; V560-F602 HydrophobicContact CG2-CD1 4.32Å; V560-F602 HydrophobicContact CG2-CE1 3.76Å; V560-F602 HydrophobicContact CG2-CE2 4.24Å; V560-F602 HydrophobicContact CG2-CZ 3.7Å; W563-F602 HydrophobicContact CB-CD2 3.64Å; W563-F602 HydrophobicContact CB-CE2 4.1Å; W563-F602 AromaticContact CD1-CD2 3.8Å; W563-F602 HydrophobicContact CD2-CB 4.33Å; W563-F602 AromaticContact CD2-CD2 3.89Å; W563-F602 HydrophobicContact CD2-CD2 3.89Å; W563-F602 HydrophobicContact CG-CB 4.13Å; W563-F602 AromaticContact CG-CD2 3.49Å; W563-F602 HydrophobicContact CG-CD2 3.49Å; W563-F602 VanDerWaalsContact CG-CD2 3.49Å; W563-F602 HydrophobicContact CG-CE2 4.39Å; W563-F602 HydrophobicContact CG-CG 4.26Å; T598-F602 PolarHBondContact O-N 2.98Å; L599-F602 WeakPolarHBondContact O-CB 3.24Å; L599-F602 PolarHBondContact O-N 2.82Å; F602-R604 VanDerWaalsContact C-N 3.32Å; F602-R604 PolarHBondContact O-N 2.97Å; F602-H605 PolarHBondContact O-N 2.77Å; F602-H605 VanDerWaalsContact O-N 3.1Å; F602-Y606 AromaticContact CE1-CD2 3.94Å; F602-Y606 HydrophobicContact CE1-CD2 3.94Å; F602-Y606 HydrophobicContact CE1-CG 4.03Å; F602-Y606 HydrophobicContact CE2-CD2 4.45Å; F602-Y606 AromaticContact CZ-CD2 3.65Å; F602-Y606 HydrophobicContact CZ-CD2 3.65Å; F602-Y606 HydrophobicContact CZ-CE2 4.3Å; F602-Y606 HydrophobicContact CZ-CG 4.2Å; F602-Y606 VanDerWaalsContact O-CB 3.27Å; F602-Y606 WeakPolarHBondContact O-CB 3.48Å; F602-Y606 PolarHBondContact O-N 2.94Å; F602-I632 HydrophobicContact CD2-CD1 4.19Å; F602-I632 HydrophobicContact CE2-CD1 3.8Å
603K98.2Very high97.3Very high6 Ų641.4 Ų41.43%0.02625%0.248CC..Hα-helixtrans-53.8-47.9179.7171.4168.4173.758.60111.7F469 S474 W475 F476 L599 C600 H605 Y606 D607F469-K603 HydrophobicContact CD1-CD 4.42Å; F469-K603 HydrophobicContact CE1-CD 4.16Å; F469-K603 HydrophobicContact CZ-CD 4.3Å; S474-K603 WeakPolarHBondContact OG-CE 3.23Å; S474-K603 PolarHBondContact OG-NZ 3.06Å; W475-K603 HydrophobicContact CH2-CB 4.11Å; W475-K603 HydrophobicContact CH2-CG 4.31Å; W475-K603 HydrophobicContact CZ2-CB 4.09Å; W475-K603 HydrophobicContact CZ2-CD 4.38Å; W475-K603 HydrophobicContact CZ2-CG 3.86Å; W475-K603 VanDerWaalsContact NE1-NZ 3.18Å; W475-K603 WeakPolarHBondContact O-CD 3.35Å; W475-K603 WeakPolarHBondContact O-CE 3.41Å; W475-K603 PolarHBondContact O-NZ 3.35Å; F476-K603 HydrophobicContact CD2-CD 3.66Å; F476-K603 HydrophobicContact CE2-CD 4.24Å; L599-K603 PolarHBondContact O-N 2.85Å; C600-K603 PolarHBondContact O-N 2.96Å; K603-H605 VanDerWaalsContact C-N 3.32Å; K603-H605 PolarHBondContact O-N 2.92Å; K603-Y606 PolarHBondContact O-N 3.39Å; K603-D607 WeakPolarHBondContact CE-OD2 3.26Å; K603-D607 VanDerWaalsContact CG-OD2 3.31Å; K603-D607 WeakPolarHBondContact CG-OD2 3.41Å; K603-D607 IonicContact NZ-OD1 2.68Å; K603-D607 PolarHBondContact NZ-OD1 3.24Å; K603-D607 IonicContact NZ-OD2 3.7Å; K603-D607 PolarHBondContact NZ-OD2 3.11Å; K603-D607 WeakPolarHBondContact O-CB 3.42Å; K603-D607 VanDerWaalsContact O-CG 3.23Å; K603-D607 PolarHBondContact O-N 3.42Å
604R98Very high97.5Very high136 Ų13646.1 Ų46.151%0.51326%0.261SS..Hα-helixtrans-58.1-42.4179.1-179.5177.755.468.99112.5C600 S601 F602 A608C600-R604 WeakPolarHBondContact O-CB 3.26Å; C600-R604 PolarHBondContact O-N 2.8Å; S601-R604 PolarHBondContact O-N 2.99Å; S601-R604 PolarHBondContact OG-NH2 3.35Å; F602-R604 VanDerWaalsContact C-N 3.32Å; F602-R604 PolarHBondContact O-N 2.97Å; R604-A608 VanDerWaalsContact O-CB 3.27Å; R604-A608 WeakPolarHBondContact O-CB 3.21Å; R604-A608 PolarHBondContact O-N 3.27Å
605H98.4Very high97.6Very high29 Ų2942.2 Ų42.213%0.13424%0.238CC..Hα-helixtrans-75.2-34.4178.4-80.4-69000112.9W563 S601 F602 K603 A608 N609 T610 V615 I632W563-H605 HydrophobicContact CH2-CB 4.38Å; W563-H605 AromaticContact CH2-CD2 3.58Å; S601-H605 PolarHBondContact O-CD2 2.65Å; S601-H605 VanDerWaalsContact O-CD2 3.31Å; S601-H605 PolarHBondContact O-N 3.34Å; F602-H605 PolarHBondContact O-N 2.77Å; F602-H605 VanDerWaalsContact O-N 3.1Å; K603-H605 VanDerWaalsContact C-N 3.32Å; K603-H605 PolarHBondContact O-N 2.92Å; H605-A608 PolarHBondContact O-N 3.29Å; H605-N609 PolarHBondContact O-N 2.95Å; H605-T610 PolarHBondContact ND1-OG1 3.08Å; H605-T610 PolarHBondContact O-N 3.35Å; H605-T610 PolarHBondContact O-OG1 3.33Å; H605-V615 HydrophobicContact CB-CG1 4.28Å; H605-I632 VanDerWaalsContact O-CG2 3.3Å; H605-I632 WeakPolarHBondContact O-CG2 3.47Å
606Y98.4Very high97.6Very high4 Ų442.2 Ų42.22%0.01624%0.238CC..Hα-helixtrans-62.9-53.5173.9-166.9-93000111W475 V555 L559 F602 K603 A608 N609 I632 H633W475-Y606 HydrophobicContact CH2-CD1 4.42Å; W475-Y606 AromaticContact CZ2-CD1 3.59Å; W475-Y606 HydrophobicContact CZ2-CD1 3.59Å; W475-Y606 HydrophobicContact CZ2-CE1 4.25Å; W475-Y606 HydrophobicContact CZ2-CG 4.18Å; V555-Y606 HydrophobicContact CG2-CD1 4.35Å; V555-Y606 HydrophobicContact CG2-CE1 3.72Å; L559-Y606 HydrophobicContact CD2-CD2 4.45Å; L559-Y606 HydrophobicContact CD2-CE2 4.06Å; F602-Y606 AromaticContact CE1-CD2 3.94Å; F602-Y606 HydrophobicContact CE1-CD2 3.94Å; F602-Y606 HydrophobicContact CE1-CG 4.03Å; F602-Y606 HydrophobicContact CE2-CD2 4.45Å; F602-Y606 AromaticContact CZ-CD2 3.65Å; F602-Y606 HydrophobicContact CZ-CD2 3.65Å; F602-Y606 HydrophobicContact CZ-CE2 4.3Å; F602-Y606 HydrophobicContact CZ-CG 4.2Å; F602-Y606 VanDerWaalsContact O-CB 3.27Å; F602-Y606 WeakPolarHBondContact O-CB 3.48Å; F602-Y606 PolarHBondContact O-N 2.94Å; K603-Y606 PolarHBondContact O-N 3.39Å; Y606-A608 PolarHBondContact O-N 3.43Å; Y606-N609 PolarHBondContact O-N 2.81Å; Y606-I632 HydrophobicContact CD2-CG1 4.35Å; Y606-H633 AromaticContact CD1-CD2 3.52Å; Y606-H633 AromaticContact CE1-CD2 3.19Å; Y606-H633 WeakPolarHBondContact CE1-CD2 3.4Å; Y606-H633 AromaticContact CE1-CG 4Å; Y606-H633 AromaticContact CE1-NE2 3.57Å; Y606-H633 AromaticContact CZ-CD2 3.69Å; Y606-H633 WeakPolarHBondContact O-CB 3.43Å
607D98Very high97.6Very high83 Ų8343.3 Ų43.344%0.44425%0.245SC..Hα-helixtrans-62.6-31.5178-65.4-15.9000112.4W475 K603 N609W475-D607 PolarHBondContact NE1-OD1 2.93Å; K603-D607 WeakPolarHBondContact CE-OD2 3.26Å; K603-D607 VanDerWaalsContact CG-OD2 3.31Å; K603-D607 WeakPolarHBondContact CG-OD2 3.41Å; K603-D607 IonicContact NZ-OD1 2.68Å; K603-D607 PolarHBondContact NZ-OD1 3.24Å; K603-D607 IonicContact NZ-OD2 3.7Å; K603-D607 PolarHBondContact NZ-OD2 3.11Å; K603-D607 WeakPolarHBondContact O-CB 3.42Å; K603-D607 VanDerWaalsContact O-CG 3.23Å; K603-D607 PolarHBondContact O-N 3.42Å; D607-N609 VanDerWaalsContact C-N 3.27Å; D607-N609 PolarHBondContact O-N 3.32Å
608A98.2Very high97.6Very high69 Ų6942.6 Ų42.657%0.5724%0.238SC*.THydrogen-bonded Turntrans-82.2-1.917600000113.9R604 H605 Y606 T610R604-A608 VanDerWaalsContact O-CB 3.27Å; R604-A608 WeakPolarHBondContact O-CB 3.21Å; R604-A608 PolarHBondContact O-N 3.27Å; H605-A608 PolarHBondContact O-N 3.29Å; Y606-A608 PolarHBondContact O-N 3.43Å; A608-T610 PolarHBondContact O-N 3.24Å
609N98.5Very high97.5Very high53 Ų5342.9 Ų42.928%0.28324%0.239SC..THydrogen-bonded Turntrans42.250.5-170.4-166.726000112.8H605 Y606 D607 G631 I632 H633 D634H605-N609 PolarHBondContact O-N 2.95Å; Y606-N609 PolarHBondContact O-N 2.81Å; D607-N609 VanDerWaalsContact C-N 3.27Å; D607-N609 PolarHBondContact O-N 3.32Å; N609-G631 WeakPolarHBondContact OD1-CA 3.36Å; N609-I632 PolarHBondContact OD1-N 3.33Å; N609-H633 HydrophobicContact CB-CB 3.73Å; N609-H633 WeakPolarHBondContact OD1-CA 3.48Å; N609-H633 WeakPolarHBondContact OD1-CB 3.1Å; N609-H633 PolarHBondContact OD1-N 2.85Å; N609-D634 PolarHBondContact ND2-OD1 2.68Å; N609-D634 PolarHBondContact ND2-OD2 3.2Å; N609-D634 PolarHBondContact OD1-N 2.87Å
610T98.4Very high97.5Very high14 Ų1443.7 Ų43.79%0.08624%0.244CC..  trans-61.4136.3-175.1-54.10000110.2H605 A608 L612 Q614 V615 G631 I632H605-T610 PolarHBondContact ND1-OG1 3.08Å; H605-T610 PolarHBondContact O-N 3.35Å; H605-T610 PolarHBondContact O-OG1 3.33Å; A608-T610 PolarHBondContact O-N 3.24Å; T610-L612 PolarHBondContact O-N 3.36Å; T610-Q614 HydrophobicContact CG2-CB 4.24Å; T610-Q614 HydrophobicContact CG2-CG 4.27Å; T610-V615 HydrophobicContact CG2-CG1 3.61Å; T610-G631 WeakPolarHBondContact O-CA 3.47Å; T610-I632 PolarHBondContact O-N 3.1Å
611P98.3Very high97.4Very high74 Ų7449.5 Ų49.548%0.48127%0.267SS..BIsolated β-bridgetrans-53.7133.4-179-28.535.6000112.9A613 Q614 V615P611-A613 PolarHBondContact O-N 3Å; P611-Q614 WeakPolarHBondContact O-CB 3.47Å; P611-Q614 PolarHBondContact O-N 3.45Å; P611-V615 WeakPolarHBondContact O-CG2 3.22Å; P611-V615 PolarHBondContact O-N 3.43Å
612L97.8Very high97.4Very high0 Ų054.4 Ų54.40%029%0.287CS..Hα-helixtrans-56.5-34.9179.3-74.5176.2000112.2T610 Q614 V615 M616 V620 Y627 M630 I632 L635T610-L612 PolarHBondContact O-N 3.36Å; L612-Q614 PolarHBondContact O-N 3.32Å; L612-Q614 VanDerWaalsContact O-N 3.07Å; L612-V615 HydrophobicContact CD2-CG2 4.28Å; L612-V615 PolarHBondContact O-N 2.88Å; L612-M616 HydrophobicContact CD2-CB 4.4Å; L612-M616 HydrophobicContact CD2-CG 4.47Å; L612-M616 HydrophobicContact CD2-SD 4.05Å; L612-M616 CarbonylContact O-C 3.58Å; L612-M616 WeakPolarHBondContact O-CA 3.42Å; L612-M616 PolarHBondContact O-N 2.79Å; L612-V620 HydrophobicContact CB-CG2 3.64Å; L612-Y627 HydrophobicContact CD1-CD1 4.13Å; L612-Y627 HydrophobicContact CD1-CG 4.25Å; L612-M630 WeakPolarHBondContact CB-O 3.33Å; L612-M630 HydrophobicContact CD1-CB 3.83Å; L612-M630 HydrophobicContact CG-CB 4.48Å; L612-M630 WeakPolarHBondContact CG-O 3.33Å; L612-M630 PolarHBondContact N-O 2.77Å; L612-I632 HydrophobicContact CD2-CB 4.01Å; L612-I632 HydrophobicContact CD2-CG1 4.33Å; L612-L635 HydrophobicContact CD1-CB 4.18Å; L612-L635 HydrophobicContact CD1-CD2 3.89Å; L612-L635 HydrophobicContact CD2-CD2 4.07Å
613A96.9Very high97.3Very high57 Ų5757.1 Ų57.147%0.47130%0.298SS..Hα-helixtrans-59.5-21.6175.900000113.7P611 V620P611-A613 PolarHBondContact O-N 3Å; A613-V620 HydrophobicContact CB-CG1 4.44Å
614Q96.8Very high97.3Very high130 Ų13059.7 Ų59.761%0.60732%0.315SS*.Hα-helixtrans-91.7-41175.7-177.1-178.7-1500112.1T610 P611 L612T610-Q614 HydrophobicContact CG2-CB 4.24Å; T610-Q614 HydrophobicContact CG2-CG 4.27Å; P611-Q614 WeakPolarHBondContact O-CB 3.47Å; P611-Q614 PolarHBondContact O-N 3.45Å; L612-Q614 PolarHBondContact O-N 3.32Å; L612-Q614 VanDerWaalsContact O-N 3.07Å
615V96.4Very high97.1Very high8 Ų861.2 Ų61.25%0.04833%0.334CS..Hα-helixtrans-94.5-29.8-171.6-74.20000114.4W563 R566 H605 T610 P611 L612 I632W563-V615 HydrophobicContact CH2-CG1 4.47Å; W563-V615 HydrophobicContact CZ3-CB 3.83Å; W563-V615 HydrophobicContact CZ3-CG1 3.96Å; R566-V615 WeakPolarHBondContact CD-O 3.43Å; R566-V615 PolarHBondContact NE-O 3.48Å; H605-V615 HydrophobicContact CB-CG1 4.28Å; T610-V615 HydrophobicContact CG2-CG1 3.61Å; P611-V615 WeakPolarHBondContact O-CG2 3.22Å; P611-V615 PolarHBondContact O-N 3.43Å; L612-V615 HydrophobicContact CD2-CG2 4.28Å; L612-V615 PolarHBondContact O-N 2.88Å; V615-I632 HydrophobicContact CG2-CB 4.12Å; V615-I632 HydrophobicContact CG2-CD1 4.33Å
616M96.3Very high97Very high14 Ų1462.9 Ų62.97%0.06935%0.346CS..  trans-139.259.9-179.1-61-179.173.800110.2L559 A562 L612 E618 L619 V620 F735L559-M616 HydrophobicContact CD1-SD 4.08Å; A562-M616 HydrophobicContact CB-CE 3.69Å; L612-M616 HydrophobicContact CD2-CB 4.4Å; L612-M616 HydrophobicContact CD2-CG 4.47Å; L612-M616 HydrophobicContact CD2-SD 4.05Å; L612-M616 CarbonylContact O-C 3.58Å; L612-M616 WeakPolarHBondContact O-CA 3.42Å; L612-M616 PolarHBondContact O-N 2.79Å; M616-E618 VanDerWaalsContact C-N 3.3Å; M616-E618 PolarHBondContact O-N 2.63Å; M616-L619 HydrophobicContact CB-CB 4.18Å; M616-L619 HydrophobicContact CE-CD2 3.95Å; M616-L619 WeakPolarHBondContact O-CB 3.37Å; M616-L619 PolarHBondContact O-N 3.07Å; M616-L619 HydrophobicContact SD-CD2 4.39Å; M616-V620 PolarHBondContact O-N 3.08Å; M616-F735 HydrophobicContact CE-CZ 4.19Å
617P96Very high96.9Very high41 Ų4162.9 Ų62.927%0.26635%0.346SS..Hα-helixtrans-60.4-34.4-17423.1-32.4000113.7R566 L619 V620 E621R566-P617 VanDerWaalsContact NH2-CD 3.28Å; P617-L619 VanDerWaalsContact C-N 3.34Å; P617-L619 PolarHBondContact O-N 3.42Å; P617-V620 PolarHBondContact O-N 3.07Å; P617-E621 WeakPolarHBondContact O-CB 3.42Å; P617-E621 PolarHBondContact O-N 3.35Å
618E95.3Very high96.8Very high102 Ų10261 Ų6148%0.47734%0.342SS..Hα-helixtrans-67.2-36.7-179.2-56.977.6-171.200111.5R566 M616 V620 E621 Q622R566-E618 IonicContact CZ-OE1 2.71Å; R566-E618 IonicContact CZ-OE2 3.9Å; R566-E618 IonicContact NH1-OE1 3.99Å; R566-E618 PolarHBondContact NH1-OE1 2.92Å; R566-E618 IonicContact NH1-OE2 3Å; R566-E618 PolarHBondContact NH1-OE2 3.28Å; R566-E618 IonicContact NH2-OE1 3.47Å; M616-E618 VanDerWaalsContact C-N 3.3Å; M616-E618 PolarHBondContact O-N 2.63Å; E618-V620 VanDerWaalsContact C-N 3.33Å; E618-V620 PolarHBondContact O-N 3.01Å; E618-E621 PolarHBondContact O-N 3.45Å; E618-Q622 WeakPolarHBondContact O-CB 3.28Å; E618-Q622 PolarHBondContact O-N 2.9Å
619L96Very high96.7Very high18 Ų1865.6 Ų65.69%0.09436%0.357CS..Hα-helixtrans-62.8-42.2174.3-179.669.5000110.8M616 P617 Y623 Y627 L635 F735M616-L619 HydrophobicContact CB-CB 4.18Å; M616-L619 HydrophobicContact CE-CD2 3.95Å; M616-L619 WeakPolarHBondContact O-CB 3.37Å; M616-L619 PolarHBondContact O-N 3.07Å; M616-L619 HydrophobicContact SD-CD2 4.39Å; P617-L619 VanDerWaalsContact C-N 3.34Å; P617-L619 PolarHBondContact O-N 3.42Å; L619-Y623 HydrophobicContact CD1-CD2 4.14Å; L619-Y623 PolarHBondContact O-N 3.41Å; L619-Y627 HydrophobicContact CD1-CD2 3.96Å; L619-Y627 HydrophobicContact CD1-CE2 3.6Å; L619-Y627 HydrophobicContact CD2-CD2 4.02Å; L619-Y627 HydrophobicContact CD2-CE2 4.11Å; L619-Y627 HydrophobicContact CD2-CG 4.32Å; L619-Y627 HydrophobicContact CG-CD2 3.59Å; L619-Y627 HydrophobicContact CG-CE2 3.75Å; L619-Y627 HydrophobicContact CG-CG 4.31Å; L619-L635 HydrophobicContact CD2-CD2 4.19Å; L619-F735 HydrophobicContact CD1-CE2 3.96Å; L619-F735 HydrophobicContact CD2-CE2 3.7Å; L619-F735 HydrophobicContact CD2-CZ 3.84Å; L619-F735 HydrophobicContact CG-CE2 4.5Å
620V97.3Very high96.7Very high17 Ų1764.9 Ų64.910%0.10335%0.353CS..Hα-helixtrans-71-37.4177.9177.80000111.8L612 A613 M616 P617 E618 Q622 Y623 P624 A628L612-V620 HydrophobicContact CB-CG2 3.64Å; A613-V620 HydrophobicContact CB-CG1 4.44Å; M616-V620 PolarHBondContact O-N 3.08Å; P617-V620 PolarHBondContact O-N 3.07Å; E618-V620 VanDerWaalsContact C-N 3.33Å; E618-V620 PolarHBondContact O-N 3.01Å; V620-Q622 VanDerWaalsContact C-N 3.32Å; V620-Y623 CarbonylContact O-C 3.57Å; V620-P624 WeakPolarHBondContact O-CA 3.49Å; V620-P624 WeakPolarHBondContact O-CB 3.41Å; V620-P624 WeakPolarHBondContact O-CD 3.37Å; V620-A628 HydrophobicContact CG1-CB 4.11Å
621E96.9Very high96.7Very high161 Ų16164.4 Ų64.475%0.75235%0.351SS*.Hα-helixtrans-63.4-39.9176.1-176.5175.5-172.500111.5P617 E618P617-E621 WeakPolarHBondContact O-CB 3.42Å; P617-E621 PolarHBondContact O-N 3.35Å; E618-E621 PolarHBondContact O-N 3.45Å
622Q96.7Very high96.7Very high126 Ų12660.9 Ų60.959%0.58933%0.328SS*.Hα-helixtrans-76.3-36.5-179.4-167.8173.2-12.300112.9E618 V620E618-Q622 WeakPolarHBondContact O-CB 3.28Å; E618-Q622 PolarHBondContact O-N 2.9Å; V620-Q622 VanDerWaalsContact C-N 3.32Å
623Y96.9Very high96.7Very high57 Ų5763.6 Ų63.622%0.22434%0.34CS..  trans-132.363.9-177.5-49.7-77.3000112.2L619 V620 D625 T626 Y627 P733L619-Y623 HydrophobicContact CD1-CD2 4.14Å; L619-Y623 PolarHBondContact O-N 3.41Å; V620-Y623 CarbonylContact O-C 3.57Å; Y623-D625 VanDerWaalsContact C-N 3.32Å; Y623-D625 PolarHBondContact O-N 3.36Å; Y623-T626 PolarHBondContact O-N 3.37Å; Y623-Y627 HydrophobicContact CD2-CE2 4.11Å; Y623-Y627 HydrophobicContact CG-CE2 4.3Å; Y623-Y627 PolarHBondContact O-N 2.81Å; Y623-Y627 VanDerWaalsContact O-N 3.09Å; Y623-P733 HydrophobicContact CD1-CB 3.6Å; Y623-P733 HydrophobicContact CD1-CG 4.05Å; Y623-P733 HydrophobicContact CD2-CB 4.09Å; Y623-P733 HydrophobicContact CE1-CB 3.48Å; Y623-P733 VanDerWaalsContact CE1-CB 3.48Å; Y623-P733 HydrophobicContact CE1-CG 4.43Å; Y623-P733 HydrophobicContact CE2-CB 4.01Å; Y623-P733 HydrophobicContact CG-CB 3.88Å; Y623-P733 HydrophobicContact CG-CG 4.08Å
624P96.7Very high96.7Very high61 Ų6163.8 Ų63.840%0.39633%0.334SS..Hα-helixtrans-64.8-36.6-172.924.9-34.3000112.5V620 T626 A628V620-P624 WeakPolarHBondContact O-CA 3.49Å; V620-P624 WeakPolarHBondContact O-CB 3.41Å; V620-P624 WeakPolarHBondContact O-CD 3.37Å; P624-T626 PolarHBondContact O-N 2.99Å; P624-A628 WeakPolarHBondContact O-CB 3.35Å; P624-A628 PolarHBondContact O-N 2.85Å; P624-A628 VanDerWaalsContact O-N 3.08Å
625D95.5Very high96.8Very high167 Ų16757.7 Ų57.789%0.89331%0.305SS*.Hα-helixtrans-63.5-26.8-179.9-64.9-28.5000112.3Y623Y623-D625 VanDerWaalsContact C-N 3.32Å; Y623-D625 PolarHBondContact O-N 3.36Å
626T95.2Very high96.9Very high65 Ų6557.3 Ų57.340%0.39930%0.303SS..Hα-helixtrans-89.7-46.9179.8-47.50000111.7Y623 P624 P733Y623-T626 PolarHBondContact O-N 3.37Å; P624-T626 PolarHBondContact O-N 2.99Å; T626-P733 HydrophobicContact CG2-CG 4.35Å
627Y97.7Very high97Very high3 Ų359.8 Ų59.81%0.01232%0.316CS..Hα-helixtrans-113.8-8.3-162.9-58.3-54.7000116.1L612 L619 Y623 N629 M630 L635 P733L612-Y627 HydrophobicContact CD1-CD1 4.13Å; L612-Y627 HydrophobicContact CD1-CG 4.25Å; L619-Y627 HydrophobicContact CD1-CD2 3.96Å; L619-Y627 HydrophobicContact CD1-CE2 3.6Å; L619-Y627 HydrophobicContact CD2-CD2 4.02Å; L619-Y627 HydrophobicContact CD2-CE2 4.11Å; L619-Y627 HydrophobicContact CD2-CG 4.32Å; L619-Y627 HydrophobicContact CG-CD2 3.59Å; L619-Y627 HydrophobicContact CG-CE2 3.75Å; L619-Y627 HydrophobicContact CG-CG 4.31Å; Y623-Y627 HydrophobicContact CD2-CE2 4.11Å; Y623-Y627 HydrophobicContact CG-CE2 4.3Å; Y623-Y627 PolarHBondContact O-N 2.81Å; Y623-Y627 VanDerWaalsContact O-N 3.09Å; Y627-N629 VanDerWaalsContact C-N 3.27Å; Y627-N629 PolarHBondContact O-N 3.22Å; Y627-N629 VanDerWaalsContact O-N 3.13Å; Y627-M630 HydrophobicContact CD1-SD 4.08Å; Y627-M630 PolarHBondContact O-N 2.94Å; Y627-L635 HydrophobicContact CD1-CD1 4.08Å; Y627-L635 HydrophobicContact CE1-CD1 3.62Å; Y627-L635 HydrophobicContact CE1-CD2 4.42Å; Y627-P733 HydrophobicContact CE2-CG 4.17Å; Y627-P733 VanDerWaalsContact CE2-O 3.24Å; Y627-P733 WeakPolarHBondContact CE2-O 3.13Å; Y627-P733 WeakPolarHBondContact OH-CD 3.39Å; Y627-P733 PolarHBondContact OH-O 2.91Å
628A95.7Very high97.1Very high45 Ų4561.1 Ų61.137%0.37232%0.324SS..THydrogen-bonded Turntrans-60.7-29.9-169.100000115.2V620 P624V620-A628 HydrophobicContact CG1-CB 4.11Å; P624-A628 WeakPolarHBondContact O-CB 3.35Å; P624-A628 PolarHBondContact O-N 2.85Å; P624-A628 VanDerWaalsContact O-N 3.08Å
629N95.5Very high97.2Very high164 Ų16456.2 Ų56.288%0.87730%0.301SS*.THydrogen-bonded Turntrans-108.315.3-175.7-60.8-54.7000113.6Y627Y627-N629 VanDerWaalsContact C-N 3.27Å; Y627-N629 PolarHBondContact O-N 3.22Å; Y627-N629 VanDerWaalsContact O-N 3.13Å
630M97.5Very high97.3Very high38 Ų3855.8 Ų55.819%0.18730%0.298CS..  trans-104.4144.8-179.7-63.6177.474.800110.9L612 Y627 D634 L635 T638L612-M630 WeakPolarHBondContact CB-O 3.33Å; L612-M630 HydrophobicContact CD1-CB 3.83Å; L612-M630 HydrophobicContact CG-CB 4.48Å; L612-M630 WeakPolarHBondContact CG-O 3.33Å; L612-M630 PolarHBondContact N-O 2.77Å; Y627-M630 HydrophobicContact CD1-SD 4.08Å; Y627-M630 PolarHBondContact O-N 2.94Å; M630-D634 HydrophobicContact CB-CB 4.28Å; M630-D634 HydrophobicContact CE-CB 4.13Å; M630-L635 VanDerWaalsContact CE-CA 3.5Å; M630-L635 HydrophobicContact CE-CB 4.03Å; M630-L635 HydrophobicContact CE-CD1 4.16Å; M630-T638 WeakPolarHBondContact CE-OG1 3.4Å
631G98.3Very high97.3Very high5 Ų557.6 Ų57.65%0.05232%0.315CS..BIsolated β-bridgetrans-86.7167.8157.800000111.7N609 T610 H633 D634 L635N609-G631 WeakPolarHBondContact OD1-CA 3.36Å; T610-G631 WeakPolarHBondContact O-CA 3.47Å; G631-H633 VanDerWaalsContact C-N 3.26Å; G631-H633 PolarHBondContact O-N 3.21Å; G631-D634 PolarHBondContact N-OD2 2.74Å; G631-D634 WeakPolarHBondContact O-CB 3Å; G631-D634 PolarHBondContact O-N 2.68Å; G631-L635 PolarHBondContact O-N 3.46Å; G631-L635 VanDerWaalsContact O-N 3.12Å
632I98.3Very high97.3Very high0 Ų050.5 Ų50.50%028%0.281CS..Hα-helixtrans-64.1-29.6-178.7-170.9171000113L559 W563 F602 H605 Y606 N609 T610 L612 V615 G636L559-I632 HydrophobicContact CD1-CG1 4.28Å; L559-I632 HydrophobicContact CD2-CG1 4.06Å; L559-I632 HydrophobicContact CG-CG1 4.41Å; W563-I632 HydrophobicContact CE3-CD1 4.21Å; F602-I632 HydrophobicContact CD2-CD1 4.19Å; F602-I632 HydrophobicContact CE2-CD1 3.8Å; H605-I632 VanDerWaalsContact O-CG2 3.3Å; H605-I632 WeakPolarHBondContact O-CG2 3.47Å; Y606-I632 HydrophobicContact CD2-CG1 4.35Å; N609-I632 PolarHBondContact OD1-N 3.33Å; T610-I632 PolarHBondContact O-N 3.1Å; L612-I632 HydrophobicContact CD2-CB 4.01Å; L612-I632 HydrophobicContact CD2-CG1 4.33Å; V615-I632 HydrophobicContact CG2-CB 4.12Å; V615-I632 HydrophobicContact CG2-CD1 4.33Å; I632-G636 PolarHBondContact O-N 3.29Å; I632-G636 VanDerWaalsContact O-N 3.09Å
633H98.3Very high97.3Very high56 Ų5644.6 Ų44.626%0.25925%0.254SS..Hα-helixtrans-71.2-43.2173.9-166.1-76.3000110.6Y606 N609 G631 L635 G636 D637Y606-H633 AromaticContact CD1-CD2 3.52Å; Y606-H633 AromaticContact CE1-CD2 3.19Å; Y606-H633 WeakPolarHBondContact CE1-CD2 3.4Å; Y606-H633 AromaticContact CE1-CG 4Å; Y606-H633 AromaticContact CE1-NE2 3.57Å; Y606-H633 AromaticContact CZ-CD2 3.69Å; Y606-H633 WeakPolarHBondContact O-CB 3.43Å; N609-H633 HydrophobicContact CB-CB 3.73Å; N609-H633 WeakPolarHBondContact OD1-CA 3.48Å; N609-H633 WeakPolarHBondContact OD1-CB 3.1Å; N609-H633 PolarHBondContact OD1-N 2.85Å; G631-H633 VanDerWaalsContact C-N 3.26Å; G631-H633 PolarHBondContact O-N 3.21Å; H633-L635 PolarHBondContact O-N 3.4Å; H633-G636 CarbonylContact O-C 3.59Å; H633-G636 WeakPolarHBondContact O-CA 2.89Å; H633-G636 PolarHBondContact O-N 3.39Å; H633-D637 IonicContact CE1-OD1 2.78Å; H633-D637 PolarHBondContact CE1-OD1 3.15Å; H633-D637 VanDerWaalsContact CE1-OD1 3.3Å; H633-D637 IonicContact CE1-OD2 3.78Å; H633-D637 PolarHBondContact CE1-OD2 3.23Å; H633-D637 IonicContact ND1-OD1 2.91Å; H633-D637 IonicContact ND1-OD2 2.92Å; H633-D637 PolarHBondContact ND1-OD2 2.81Å; H633-D637 PolarHBondContact O-N 3.34Å
634D98.4Very high97.3Very high62 Ų6246.4 Ų46.433%0.33226%0.263SS..Hα-helixtrans-58.2-38.3177.5-55.7-41.7000111.2N609 M630 G631 T638N609-D634 PolarHBondContact ND2-OD1 2.68Å; N609-D634 PolarHBondContact ND2-OD2 3.2Å; N609-D634 PolarHBondContact OD1-N 2.87Å; M630-D634 HydrophobicContact CB-CB 4.28Å; M630-D634 HydrophobicContact CE-CB 4.13Å; G631-D634 PolarHBondContact N-OD2 2.74Å; G631-D634 WeakPolarHBondContact O-CB 3Å; G631-D634 PolarHBondContact O-N 2.68Å; D634-T638 WeakPolarHBondContact O-CB 3.38Å; D634-T638 PolarHBondContact O-N 2.81Å; D634-T638 PolarHBondContact O-OG1 2.89Å
635L98.1Very high97.2Very high1 Ų151.1 Ų51.11%0.00528%0.279CS..Hα-helixtrans-66.8-44.1173.9-178.557.7000111.8L559 L612 L619 Y627 M630 G631 H633 D637 T638 M639 F735L559-L635 HydrophobicContact CD1-CD2 3.81Å; L559-L635 HydrophobicContact CD1-CG 4.37Å; L612-L635 HydrophobicContact CD1-CB 4.18Å; L612-L635 HydrophobicContact CD1-CD2 3.89Å; L612-L635 HydrophobicContact CD2-CD2 4.07Å; L619-L635 HydrophobicContact CD2-CD2 4.19Å; Y627-L635 HydrophobicContact CD1-CD1 4.08Å; Y627-L635 HydrophobicContact CE1-CD1 3.62Å; Y627-L635 HydrophobicContact CE1-CD2 4.42Å; M630-L635 VanDerWaalsContact CE-CA 3.5Å; M630-L635 HydrophobicContact CE-CB 4.03Å; M630-L635 HydrophobicContact CE-CD1 4.16Å; G631-L635 PolarHBondContact O-N 3.46Å; G631-L635 VanDerWaalsContact O-N 3.12Å; H633-L635 PolarHBondContact O-N 3.4Å; L635-D637 VanDerWaalsContact C-N 3.35Å; L635-D637 PolarHBondContact O-N 3Å; L635-T638 PolarHBondContact O-N 3.46Å; L635-M639 HydrophobicContact CD1-CE 3.95Å; L635-M639 HydrophobicContact CD1-CG 4.34Å; L635-M639 HydrophobicContact CD1-SD 4.47Å; L635-M639 HydrophobicContact CD2-CE 4.28Å; L635-M639 HydrophobicContact CG-CE 4.06Å; L635-M639 HydrophobicContact CG-SD 4.27Å; L635-M639 WeakPolarHBondContact O-CB 3.07Å; L635-M639 WeakPolarHBondContact O-CG 3.34Å; L635-M639 PolarHBondContact O-N 3.42Å; L635-F735 HydrophobicContact CD2-CE2 4.11Å; L635-F735 HydrophobicContact CD2-CZ 3.97Å
636G98.1Very high97.1Very high0 Ų044.4 Ų44.40%024%0.244CC..Hα-helixtrans-57.7-45.4174.300000112.7I632 H633 M639 F640I632-G636 PolarHBondContact O-N 3.29Å; I632-G636 VanDerWaalsContact O-N 3.09Å; H633-G636 CarbonylContact O-C 3.59Å; H633-G636 WeakPolarHBondContact O-CA 2.89Å; H633-G636 PolarHBondContact O-N 3.39Å; G636-M639 PolarHBondContact O-N 3.15Å; G636-F640 VanDerWaalsContact O-CB 3.27Å; G636-F640 WeakPolarHBondContact O-CB 3.36Å; G636-F640 PolarHBondContact O-N 3.21Å
637D97.9Very high97Very high66 Ų6643.5 Ų43.535%0.35324%0.236SC..Hα-helixtrans-63.7-41.7177-74.6-26.2000111.5H633 L635 F640 A641H633-D637 IonicContact CE1-OD1 2.78Å; H633-D637 PolarHBondContact CE1-OD1 3.15Å; H633-D637 VanDerWaalsContact CE1-OD1 3.3Å; H633-D637 IonicContact CE1-OD2 3.78Å; H633-D637 PolarHBondContact CE1-OD2 3.23Å; H633-D637 IonicContact ND1-OD1 2.91Å; H633-D637 IonicContact ND1-OD2 2.92Å; H633-D637 PolarHBondContact ND1-OD2 2.81Å; H633-D637 PolarHBondContact O-N 3.34Å; L635-D637 VanDerWaalsContact C-N 3.35Å; L635-D637 PolarHBondContact O-N 3Å; D637-F640 PolarHBondContact O-N 3.47Å; D637-A641 VanDerWaalsContact O-CB 3.28Å; D637-A641 WeakPolarHBondContact O-CB 3.42Å; D637-A641 PolarHBondContact O-N 3.41Å
638T97.7Very high96.7Very high69 Ų6943.8 Ų43.842%0.42324%0.239SC..Hα-helixtrans-63.5-46.2177.7-56.50000111.2M630 D634 L635 W642 F732M630-T638 WeakPolarHBondContact CE-OG1 3.4Å; D634-T638 WeakPolarHBondContact O-CB 3.38Å; D634-T638 PolarHBondContact O-N 2.81Å; D634-T638 PolarHBondContact O-OG1 2.89Å; L635-T638 PolarHBondContact O-N 3.46Å; T638-W642 PolarHBondContact O-N 2.89Å; T638-W642 VanDerWaalsContact O-N 3.16Å; T638-F732 HydrophobicContact CG2-CE1 4.03Å
639M98Very high96.5Very high0 Ų042 Ų420%022%0.224CC..Hα-helixtrans-63.1-44.8175.2-78.1177.6173.500111.9P556 L559 L635 G636 W642 L643 W728 F732 F735P556-M639 HydrophobicContact CB-CB 4.1Å; P556-M639 HydrophobicContact CB-SD 4.34Å; P556-M639 HydrophobicContact CG-CB 3.59Å; L559-M639 HydrophobicContact CB-SD 4.05Å; L635-M639 HydrophobicContact CD1-CE 3.95Å; L635-M639 HydrophobicContact CD1-CG 4.34Å; L635-M639 HydrophobicContact CD1-SD 4.47Å; L635-M639 HydrophobicContact CD2-CE 4.28Å; L635-M639 HydrophobicContact CG-CE 4.06Å; L635-M639 HydrophobicContact CG-SD 4.27Å; L635-M639 WeakPolarHBondContact O-CB 3.07Å; L635-M639 WeakPolarHBondContact O-CG 3.34Å; L635-M639 PolarHBondContact O-N 3.42Å; G636-M639 PolarHBondContact O-N 3.15Å; M639-W642 WeakPolarHBondContact O-CB 3.32Å; M639-W642 PolarHBondContact O-N 2.89Å; M639-L643 WeakPolarHBondContact O-CG 3.49Å; M639-L643 PolarHBondContact O-N 3.01Å; M639-W728 HydrophobicContact CB-CH2 4.27Å; M639-W728 HydrophobicContact CG-CH2 4.13Å; M639-W728 HydrophobicContact SD-CH2 4.38Å; M639-F732 HydrophobicContact CB-CE1 4.26Å; M639-F732 HydrophobicContact CB-CZ 4.25Å; M639-F732 HydrophobicContact CE-CB 4.33Å; M639-F732 HydrophobicContact CE-CD1 4.01Å; M639-F732 HydrophobicContact CE-CG 4.25Å; M639-F732 HydrophobicContact CG-CD1 3.7Å; M639-F732 HydrophobicContact CG-CE1 3.48Å; M639-F732 VanDerWaalsContact CG-CE1 3.48Å; M639-F732 HydrophobicContact CG-CE2 4.37Å; M639-F732 HydrophobicContact CG-CG 4.25Å; M639-F732 HydrophobicContact CG-CZ 3.86Å; M639-F735 HydrophobicContact CE-CB 4.32Å; M639-F735 HydrophobicContact CE-CD1 3.65Å; M639-F735 HydrophobicContact CE-CD2 3.43Å; M639-F735 VanDerWaalsContact CE-CD2 3.43Å; M639-F735 HydrophobicContact CE-CE1 3.68Å; M639-F735 HydrophobicContact CE-CE2 3.46Å; M639-F735 VanDerWaalsContact CE-CE2 3.46Å; M639-F735 HydrophobicContact CE-CG 3.52Å; M639-F735 HydrophobicContact CE-CZ 3.59Å
640F97.8Very high96.3Very high8 Ų835.8 Ų35.84%0.03520%0.196CC..Hα-helixtrans-67.1-38-180-173.2-110.2000112.3E551 T553 G554 P556 F577 G636 D637 W642 L643 K644E551-F640 WeakPolarHBondContact O-CZ 3.4Å; T553-F640 VanDerWaalsContact C-CZ 3.44Å; T553-F640 VanDerWaalsContact CA-CE1 3.43Å; G554-F640 VanDerWaalsContact N-CE1 3.33Å; P556-F640 HydrophobicContact CG-CB 4.09Å; F577-F640 AromaticContact CE1-CD2 3.96Å; F577-F640 HydrophobicContact CE1-CD2 3.96Å; F577-F640 AromaticContact CE1-CE2 3.82Å; F577-F640 HydrophobicContact CE1-CE2 3.82Å; F577-F640 AromaticContact CZ-CD2 3.92Å; F577-F640 HydrophobicContact CZ-CD2 3.92Å; F577-F640 AromaticContact CZ-CE2 3.64Å; F577-F640 HydrophobicContact CZ-CE2 3.64Å; G636-F640 VanDerWaalsContact O-CB 3.27Å; G636-F640 WeakPolarHBondContact O-CB 3.36Å; G636-F640 PolarHBondContact O-N 3.21Å; D637-F640 PolarHBondContact O-N 3.47Å; F640-W642 VanDerWaalsContact C-N 3.31Å; F640-W642 PolarHBondContact O-N 2.92Å; F640-L643 HydrophobicContact CD2-CD1 4.41Å; F640-L643 WeakPolarHBondContact O-CB 3.27Å; F640-L643 PolarHBondContact O-N 3.47Å; F640-K644 HydrophobicContact CD1-CD 3.97Å; F640-K644 HydrophobicContact CD1-CG 4.43Å; F640-K644 HydrophobicContact CE1-CD 3.49Å; F640-K644 VanDerWaalsContact CE1-CD 3.49Å; F640-K644 HydrophobicContact CE1-CG 4.08Å; F640-K644 HydrophobicContact CZ-CD 3.98Å; F640-K644 HydrophobicContact CZ-CG 4.19Å; F640-K644 WeakPolarHBondContact O-CG 3.5Å; F640-K644 PolarHBondContact O-N 2.98Å
641A97.7Very high96.1Very high55 Ų5536.9 Ų36.946%0.45520%0.198SC..Hα-helixtrans-59.5-42.7172.600000111.6D637 K644 E645D637-A641 VanDerWaalsContact O-CB 3.28Å; D637-A641 WeakPolarHBondContact O-CB 3.42Å; D637-A641 PolarHBondContact O-N 3.41Å; A641-K644 PolarHBondContact O-N 2.95Å; A641-E645 PolarHBondContact O-N 2.76Å
642W97.7Very high95.8Very high13 Ų1337.6 Ų37.65%0.04920%0.2CC..Hα-helixtrans-64-41.7174.4-173.7103.2000112.1T638 M639 F640 K644 E645 N646 P648 S724 W728 H731 F732T638-W642 PolarHBondContact O-N 2.89Å; T638-W642 VanDerWaalsContact O-N 3.16Å; M639-W642 WeakPolarHBondContact O-CB 3.32Å; M639-W642 PolarHBondContact O-N 2.89Å; F640-W642 VanDerWaalsContact C-N 3.31Å; F640-W642 PolarHBondContact O-N 2.92Å; W642-K644 VanDerWaalsContact C-N 3.29Å; W642-K644 PolarHBondContact O-N 3.43Å; W642-E645 PolarHBondContact O-N 2.9Å; W642-N646 HydrophobicContact CD2-CB 4.09Å; W642-N646 VanDerWaalsContact CE2-ND2 3.32Å; W642-N646 HydrophobicContact CE3-CB 3.98Å; W642-N646 HydrophobicContact CH2-CB 3.78Å; W642-N646 HydrophobicContact CZ2-CB 3.88Å; W642-N646 HydrophobicContact CZ3-CB 3.82Å; W642-N646 PolarHBondContact NE1-ND2 3.31Å; W642-N646 WeakPolarHBondContact O-CB 3.47Å; W642-N646 PolarHBondContact O-N 3.3Å; W642-N646 PolarHBondContact O-ND2 3.35Å; W642-N646 VanDerWaalsContact O-ND2 3.09Å; W642-P648 HydrophobicContact CZ3-CB 4.23Å; W642-P648 HydrophobicContact CZ3-CG 3.79Å; W642-S724 WeakPolarHBondContact CH2-O 3.31Å; W642-W728 HydrophobicContact CD2-CE3 4.01Å; W642-W728 HydrophobicContact CD2-CZ3 4.49Å; W642-W728 AromaticContact CE3-CE3 3.41Å; W642-W728 HydrophobicContact CE3-CE3 3.41Å; W642-W728 VanDerWaalsContact CE3-CE3 3.41Å; W642-W728 AromaticContact CE3-CZ3 3.78Å; W642-W728 HydrophobicContact CE3-CZ3 3.78Å; W642-W728 HydrophobicContact CH2-CB 3.77Å; W642-W728 HydrophobicContact CH2-CE3 4Å; W642-W728 HydrophobicContact CZ2-CB 3.91Å; W642-W728 HydrophobicContact CZ3-CB 4.38Å; W642-W728 HydrophobicContact CZ3-CD2 4.43Å; W642-W728 AromaticContact CZ3-CE3 3.43Å; W642-W728 HydrophobicContact CZ3-CE3 3.43Å; W642-W728 VanDerWaalsContact CZ3-CE3 3.43Å; W642-W728 HydrophobicContact CZ3-CZ3 4.1Å; W642-H731 AromaticContact CD1-CD2 3.98Å; W642-H731 AromaticContact CD1-CG 3.83Å; W642-H731 AromaticContact NE1-CE1 3.84Å; W642-H731 AromaticContact NE1-CG 3.62Å; W642-H731 AromaticContact NE1-ND1 3.45Å; W642-H731 PolarHBondContact NE1-ND1 3.01Å; W642-F732 HydrophobicContact CB-CE2 3.79Å; W642-F732 HydrophobicContact CB-CZ 3.67Å; W642-F732 AromaticContact CD1-CE2 3.96Å; W642-F732 AromaticContact CD2-CE2 4Å; W642-F732 HydrophobicContact CD2-CE2 4Å; W642-F732 AromaticContact CG-CE2 3.64Å; W642-F732 HydrophobicContact CG-CE2 3.64Å; W642-F732 AromaticContact CG-CZ 3.98Å; W642-F732 HydrophobicContact CG-CZ 3.98Å
643L96.8Very high95.6Very high2 Ų239.3 Ų39.31%0.0121%0.209CC..Hα-helixtrans-59.1-40.7175.4-70174.6000111.2L550 P556 D576 F577 M639 F640 N647 P648 W728L550-L643 WeakPolarHBondContact CD1-O 3.22Å; P556-L643 HydrophobicContact CB-CD1 4.16Å; P556-L643 HydrophobicContact CG-CD1 4.17Å; D576-L643 HydrophobicContact CB-CD2 4.45Å; F577-L643 HydrophobicContact CE1-CD1 4.35Å; F577-L643 HydrophobicContact CE2-CD1 4.44Å; F577-L643 HydrophobicContact CZ-CD1 3.82Å; M639-L643 WeakPolarHBondContact O-CG 3.49Å; M639-L643 PolarHBondContact O-N 3.01Å; F640-L643 HydrophobicContact CD2-CD1 4.41Å; F640-L643 WeakPolarHBondContact O-CB 3.27Å; F640-L643 PolarHBondContact O-N 3.47Å; L643-N647 WeakPolarHBondContact O-CA 3.29Å; L643-N647 PolarHBondContact O-N 2.79Å; L643-P648 HydrophobicContact CD2-CG 3.53Å; L643-W728 HydrophobicContact CD2-CE3 4.46Å; L643-W728 HydrophobicContact CD2-CZ3 3.77Å; L643-W728 HydrophobicContact CG-CZ3 4.11Å
644K95.5Very high95.3Very high95 Ų9541.6 Ų41.641%0.41322%0.22SC..Hα-helixtrans-65.6-40.1175.9-71.9-177.969.5146.90113.3L550 E551 E552 F640 A641 W642L550-K644 HydrophobicContact CB-CG 4.09Å; L550-K644 HydrophobicContact CD1-CB 4.39Å; L550-K644 HydrophobicContact CD1-CG 3.98Å; E551-K644 PolarHBondContact O-NZ 2.89Å; E552-K644 PolarHBondContact O-NZ 3.35Å; F640-K644 HydrophobicContact CD1-CD 3.97Å; F640-K644 HydrophobicContact CD1-CG 4.43Å; F640-K644 HydrophobicContact CE1-CD 3.49Å; F640-K644 VanDerWaalsContact CE1-CD 3.49Å; F640-K644 HydrophobicContact CE1-CG 4.08Å; F640-K644 HydrophobicContact CZ-CD 3.98Å; F640-K644 HydrophobicContact CZ-CG 4.19Å; F640-K644 WeakPolarHBondContact O-CG 3.5Å; F640-K644 PolarHBondContact O-N 2.98Å; A641-K644 PolarHBondContact O-N 2.95Å; W642-K644 VanDerWaalsContact C-N 3.29Å; W642-K644 PolarHBondContact O-N 3.43Å
645E95.3Very high95.1Very high159 Ų15938.7 Ų38.774%0.74321%0.205SC*.Hα-helixtrans-72.7-39.4180-176.1175.7-170.100112.3A641 W642A641-E645 PolarHBondContact O-N 2.76Å; W642-E645 PolarHBondContact O-N 2.9Å
646N94.3Very high94.9Very high27 Ų2739.6 Ų39.614%0.14421%0.208CC..Hα-helixtrans-103.3-22.9-169.6-69-85.2000114.4W642 R651W642-N646 HydrophobicContact CD2-CB 4.09Å; W642-N646 VanDerWaalsContact CE2-ND2 3.32Å; W642-N646 HydrophobicContact CE3-CB 3.98Å; W642-N646 HydrophobicContact CH2-CB 3.78Å; W642-N646 HydrophobicContact CZ2-CB 3.88Å; W642-N646 HydrophobicContact CZ3-CB 3.82Å; W642-N646 PolarHBondContact NE1-ND2 3.31Å; W642-N646 WeakPolarHBondContact O-CB 3.47Å; W642-N646 PolarHBondContact O-N 3.3Å; W642-N646 PolarHBondContact O-ND2 3.35Å; W642-N646 VanDerWaalsContact O-ND2 3.09Å; N646-R651 PolarHBondContact O-NE 3.01Å; N646-R651 VanDerWaalsContact O-NE 3.12Å; N646-R651 PolarHBondContact O-NH2 3.46Å
647N92.2Very high94.5Very high45 Ų4543.5 Ų43.524%0.24124%0.236CC..  trans40.860.8-178.9-161.1-10.4000113.7L643 G649 A650 R651L643-N647 WeakPolarHBondContact O-CA 3.29Å; L643-N647 PolarHBondContact O-N 2.79Å; N647-G649 VanDerWaalsContact C-N 3.27Å; N647-G649 PolarHBondContact O-N 3.12Å; N647-A650 HydrophobicContact CB-CB 4.34Å; N647-A650 PolarHBondContact O-N 3.47Å; N647-A650 WeakPolarHBondContact OD1-CB 3.43Å; N647-A650 PolarHBondContact OD1-N 3.3Å; N647-R651 PolarHBondContact O-N 3.13Å
648P92.4Very high93.9Very high10 Ų1042 Ų427%0.06524%0.236CC..Hα-helixtrans-60.2-35.1-177.829.8-39.7000112.5W642 L643 A650 R651 L652W642-P648 HydrophobicContact CZ3-CB 4.23Å; W642-P648 HydrophobicContact CZ3-CG 3.79Å; L643-P648 HydrophobicContact CD2-CG 3.53Å; P648-A650 PolarHBondContact O-N 3.01Å; P648-R651 CarbonylContact O-C 3.6Å; P648-R651 WeakPolarHBondContact O-CB 3.2Å; P648-R651 PolarHBondContact O-N 2.61Å; P648-R651 VanDerWaalsContact O-N 3.14Å; P648-L652 WeakPolarHBondContact O-CB 3.29Å; P648-L652 PolarHBondContact O-N 2.64Å
649G90.5Very high93.6Very high6 Ų642.2 Ų42.26%0.06223%0.234CC..Hα-helixtrans-60-40177.100000113.6D576 N647 L652 N653D576-G649 VanDerWaalsContact OD2-CA 3.22Å; D576-G649 WeakPolarHBondContact OD2-CA 3.37Å; D576-G649 PolarHBondContact OD2-N 3.02Å; N647-G649 VanDerWaalsContact C-N 3.27Å; N647-G649 PolarHBondContact O-N 3.12Å; G649-L652 PolarHBondContact O-N 2.89Å; G649-N653 PolarHBondContact O-N 3.45Å
650A91.3Very high93.4Very high34 Ų3442.9 Ų42.928%0.28124%0.238SC..Hα-helixtrans-64.2-44.5172.400000111.5N647 P648 L652 N653 E654N647-A650 HydrophobicContact CB-CB 4.34Å; N647-A650 PolarHBondContact O-N 3.47Å; N647-A650 WeakPolarHBondContact OD1-CB 3.43Å; N647-A650 PolarHBondContact OD1-N 3.3Å; P648-A650 PolarHBondContact O-N 3.01Å; A650-L652 VanDerWaalsContact C-N 3.35Å; A650-L652 PolarHBondContact O-N 2.82Å; A650-N653 PolarHBondContact O-N 2.98Å; A650-E654 WeakPolarHBondContact O-CG 3.37Å; A650-E654 PolarHBondContact O-N 3.03Å
651R93.2Very high93.2Very high62 Ų6246 Ų4623%0.23426%0.258CS..Hα-helixtrans-62.6-39.9177.2-63.3177.7-177.4169.80.8112.3N646 N647 P648 E654 A655 Y721 S724N646-R651 PolarHBondContact O-NE 3.01Å; N646-R651 VanDerWaalsContact O-NE 3.12Å; N646-R651 PolarHBondContact O-NH2 3.46Å; N647-R651 PolarHBondContact O-N 3.13Å; P648-R651 CarbonylContact O-C 3.6Å; P648-R651 WeakPolarHBondContact O-CB 3.2Å; P648-R651 PolarHBondContact O-N 2.61Å; P648-R651 VanDerWaalsContact O-N 3.14Å; R651-E654 PolarHBondContact O-N 3.27Å; R651-A655 VanDerWaalsContact O-CB 3.28Å; R651-A655 WeakPolarHBondContact O-CB 3.47Å; R651-A655 PolarHBondContact O-N 2.82Å; R651-Y721 HydrophobicContact CB-CD2 4.1Å; R651-S724 VanDerWaalsContact NH1-CB 3.35Å; R651-S724 PolarHBondContact NH1-OG 3.15Å
652L93.3Very high93.1Very high20 Ų2044 Ų4411%0.10524%0.242CC..Hα-helixtrans-57.6-53.3172.4176.9160.5000109.8P648 G649 A650 E654 A655 Y656 Y721P648-L652 WeakPolarHBondContact O-CB 3.29Å; P648-L652 PolarHBondContact O-N 2.64Å; G649-L652 PolarHBondContact O-N 2.89Å; A650-L652 VanDerWaalsContact C-N 3.35Å; A650-L652 PolarHBondContact O-N 2.82Å; L652-E654 VanDerWaalsContact C-N 3.33Å; L652-E654 PolarHBondContact O-N 3.28Å; L652-A655 PolarHBondContact O-N 3.47Å; L652-Y656 HydrophobicContact CD2-CD2 4.15Å; L652-Y656 HydrophobicContact CG-CD2 4.18Å; L652-Y656 HydrophobicContact CG-CE2 4.31Å; L652-Y656 WeakPolarHBondContact O-CD2 3.25Å; L652-Y656 PolarHBondContact O-N 2.9Å; L652-Y656 VanDerWaalsContact O-N 3.13Å; L652-Y721 HydrophobicContact CB-CD2 4.1Å; L652-Y721 HydrophobicContact CB-CE1 4.2Å; L652-Y721 HydrophobicContact CB-CE2 3.71Å; L652-Y721 HydrophobicContact CD1-CE1 4.5Å; L652-Y721 HydrophobicContact CD1-CE2 4.49Å; L652-Y721 WeakPolarHBondContact CD1-OH 3.47Å; L652-Y721 HydrophobicContact CG-CE1 4.23Å; L652-Y721 HydrophobicContact CG-CE2 4.43Å
653N92.5Very high92.9Very high35 Ų3547.9 Ų47.919%0.18726%0.26CS..Hα-helixtrans-60.9-42.4-178.3-79.2-20.9000111.7N278 G649 A650 Y656 S657N278-N653 PolarHBondContact O-ND2 2.96Å; G649-N653 PolarHBondContact O-N 3.45Å; A650-N653 PolarHBondContact O-N 2.98Å; N653-Y656 PolarHBondContact O-N 3.05Å; N653-S657 WeakPolarHBondContact O-CB 3.24Å; N653-S657 PolarHBondContact O-N 3.09Å; N653-S657 PolarHBondContact O-OG 2.88Å
654E93.3Very high92.8Very high105 Ų10549.6 Ų49.649%0.49127%0.271SS..Hα-helixtrans-60.5-46.9174.2-72.5178.8-178.800111.8A650 R651 L652 Y656 S657 P717A650-E654 WeakPolarHBondContact O-CG 3.37Å; A650-E654 PolarHBondContact O-N 3.03Å; R651-E654 PolarHBondContact O-N 3.27Å; L652-E654 VanDerWaalsContact C-N 3.33Å; L652-E654 PolarHBondContact O-N 3.28Å; E654-Y656 PolarHBondContact O-N 3.18Å; E654-S657 WeakPolarHBondContact CA-OG 3.45Å; E654-S657 PolarHBondContact O-N 3.26Å; E654-S657 PolarHBondContact O-OG 2.99Å; E654-P717 HydrophobicContact CB-CB 4.1Å
655A94.1Very high92.9Very high1 Ų145.5 Ų45.51%0.00825%0.254CS..Hα-helixtrans-60.2-30.1-179.300000114R651 L652 M704 P717 Q718 Y721R651-A655 VanDerWaalsContact O-CB 3.28Å; R651-A655 WeakPolarHBondContact O-CB 3.47Å; R651-A655 PolarHBondContact O-N 2.82Å; L652-A655 PolarHBondContact O-N 3.47Å; A655-M704 HydrophobicContact CB-CG 4.12Å; A655-M704 HydrophobicContact CB-SD 3.96Å; A655-P717 HydrophobicContact CB-CB 4.36Å; A655-Q718 PolarHBondContact O-NE2 3Å; A655-Y721 HydrophobicContact CB-CD1 4.22Å; A655-Y721 HydrophobicContact CB-CG 4.38Å
656Y93.3Very high93Very high19 Ų1938.1 Ų38.18%0.07522%0.219CC..Hα-helixtrans-98.6-14.2177.4-76.7-81000114.5R277 L652 N653 E654 I702 M704R277-Y656 VanDerWaalsContact NH2-CD1 3.27Å; L652-Y656 HydrophobicContact CD2-CD2 4.15Å; L652-Y656 HydrophobicContact CG-CD2 4.18Å; L652-Y656 HydrophobicContact CG-CE2 4.31Å; L652-Y656 WeakPolarHBondContact O-CD2 3.25Å; L652-Y656 PolarHBondContact O-N 2.9Å; L652-Y656 VanDerWaalsContact O-N 3.13Å; N653-Y656 PolarHBondContact O-N 3.05Å; E654-Y656 PolarHBondContact O-N 3.18Å; Y656-I702 HydrophobicContact CE1-CG2 4.2Å; Y656-I702 PolarHBondContact OH-O 3.01Å; Y656-M704 HydrophobicContact CE1-CB 4.26Å; Y656-M704 HydrophobicContact CE2-CB 4.35Å; Y656-M704 HydrophobicContact CE2-CG 4.46Å
657S89.3Confident93.1Very high82 Ų8239.6 Ų39.657%0.57322%0.223SC*.Hα-helixtrans-76.1-28.5-179.767.30000113.5N653 E654N653-S657 WeakPolarHBondContact O-CB 3.24Å; N653-S657 PolarHBondContact O-N 3.09Å; N653-S657 PolarHBondContact O-OG 2.88Å; E654-S657 WeakPolarHBondContact CA-OG 3.45Å; E654-S657 PolarHBondContact O-N 3.26Å; E654-S657 PolarHBondContact O-OG 2.99Å
658G85.1Confident93.3Very high35 Ų3542.2 Ų42.236%0.36123%0.234SC..SBendtrans-107.2156.3177.300000112.1
659L92.3Very high93.6Very high73 Ų7341.7 Ų41.738%0.38223%0.231SC..PPolyproline II helixtrans-95.4126.7171.9-68.9173.7000110.1R253 Y272 V274R253-L659 HydrophobicContact CG-CD2 3.89Å; Y272-L659 HydrophobicContact CD2-CD2 4.25Å; Y272-L659 HydrophobicContact CG-CD2 4.32Å; V274-L659 HydrophobicContact CG2-CD1 3.85Å; V274-L659 HydrophobicContact CG2-CD2 3.93Å; V274-L659 HydrophobicContact CG2-CG 3.75Å
660P94Very high93.9Very high14 Ų1446.9 Ų46.99%0.09125%0.249CC..PPolyproline II helixtrans-56.5155.5163.7-2334000111.6A662 L705 E709 Q718P660-A662 PolarHBondContact O-N 3.17Å; P660-L705 HydrophobicContact CB-CD1 3.73Å; P660-L705 HydrophobicContact CG-CD1 3.62Å; P660-L705 HydrophobicContact CG-CG 4.45Å; P660-E709 HydrophobicContact CB-CB 3.9Å; P660-E709 HydrophobicContact CB-CG 4.25Å; P660-Q718 HydrophobicContact CG-CG 4.22Å
661V94.2Very high94.3Very high75 Ų7548.8 Ų48.846%0.45525%0.254SS..PPolyproline II helixtrans-74.5116.8174.6-179.30000108.9P304 E663 E709 N710P304-V661 HydrophobicContact CG-CG1 4.06Å; V661-E663 HydrophobicContact CG1-CG 4.28Å; V661-E663 PolarHBondContact O-N 2.89Å; V661-E709 CarbonylContact O-C 3.51Å; V661-E709 WeakPolarHBondContact O-CA 3.45Å; V661-N710 PolarHBondContact O-N 3.09Å
662A94.5Very high94.5Very high13 Ų1346.2 Ų46.211%0.10725%0.247CC..BIsolated β-bridgetrans-79.397.3172.200000109.9L305 P660 E709L305-A662 HydrophobicContact CD1-CB 3.64Å; L305-A662 HydrophobicContact CG-CB 4Å; P660-A662 PolarHBondContact O-N 3.17Å; A662-E709 HydrophobicContact CB-CG 4.09Å
663E93.8Very high94.7Very high93 Ų9348 Ų4844%0.43526%0.256SS..  trans-79-40.4-176.6-69.3-72.4-177.600111.6V661 I690 G708 N710V661-E663 HydrophobicContact CG1-CG 4.28Å; V661-E663 PolarHBondContact O-N 2.89Å; E663-I690 HydrophobicContact CB-CD1 3.79Å; E663-I690 HydrophobicContact CB-CG1 4.13Å; E663-I690 HydrophobicContact CG-CD1 4.21Å; E663-I690 HydrophobicContact CG-CG1 4.21Å; E663-G708 PolarHBondContact N-O 2.97Å; E663-N710 HydrophobicContact CG-CB 3.88Å
664V95.6Very high95Very high38 Ų3850.6 Ų50.623%0.2327%0.273CS..SBendtrans-130.8160.4175.4-58.50000109.9E668 A669 I690 G708V664-E668 HydrophobicContact CB-CB 3.91Å; V664-E668 HydrophobicContact CG2-CB 4.26Å; V664-A669 HydrophobicContact CG2-CB 4.19Å; V664-I690 HydrophobicContact CG2-CG2 4.07Å; V664-G708 VanDerWaalsContact CG2-CA 3.45Å; V664-G708 PolarHBondContact N-O 3.21Å; V664-G708 VanDerWaalsContact N-O 3.17Å; V664-G708 WeakPolarHBondContact O-CA 3.5Å
665T96.4Very high95.2Very high10 Ų1051.5 Ų51.56%0.06128%0.281CS..  trans-68.5155.917661.10000111.2K269 L305 R667 E668 A669K269-T665 HydrophobicContact CG-CG2 4.25Å; L305-T665 HydrophobicContact CD1-CG2 4.36Å; L305-T665 HydrophobicContact CD2-CG2 4.15Å; T665-R667 PolarHBondContact O-N 2.8Å; T665-R667 VanDerWaalsContact O-N 3.11Å; T665-E668 WeakPolarHBondContact CB-OE2 3.29Å; T665-E668 WeakPolarHBondContact CG2-OE2 3.49Å; T665-E668 PolarHBondContact N-OE2 3.35Å; T665-E668 PolarHBondContact O-N 2.93Å; T665-E668 VanDerWaalsContact OG1-CG 3.3Å; T665-E668 WeakPolarHBondContact OG1-CG 3.28Å; T665-E668 PolarHBondContact OG1-N 2.89Å; T665-E668 PolarHBondContact OG1-OE2 3.48Å; T665-A669 PolarHBondContact O-N 3.44Å
666P96.9Very high95.3Very high3 Ų357.1 Ų57.12%0.01931%0.311CS..Hα-helixtrans-53.5-33.2172.5-30.537000113.6E260 L263 M264 Y670 S707E260-P666 HydrophobicContact CG-CB 4.41Å; L263-P666 HydrophobicContact CB-CB 4.23Å; L263-P666 HydrophobicContact CB-CG 4.06Å; L263-P666 HydrophobicContact CD1-CG 4.28Å; M264-P666 HydrophobicContact CG-CB 3.79Å; P666-Y670 WeakPolarHBondContact O-CB 3.37Å; P666-Y670 PolarHBondContact O-N 3.15Å; P666-S707 VanDerWaalsContact CA-OG 3.29Å; P666-S707 WeakPolarHBondContact CA-OG 3.42Å; P666-S707 WeakPolarHBondContact CB-OG 3.29Å; P666-S707 PolarHBondContact O-OG 2.86Å
667R97.3Very high95.6Very high58 Ų5859.7 Ų59.722%0.21933%0.326CS..Hα-helixtrans-66.3-45.4174.5179-177-73.5-178-18112.5D245 M264 L265 T266 G267 T665 A669 Y670 N671D245-R667 VanDerWaalsContact CG-NH1 3.33Å; D245-R667 IonicContact OD1-CZ 3.53Å; D245-R667 IonicContact OD1-NH1 3.87Å; D245-R667 PolarHBondContact OD1-NH1 3.21Å; M264-R667 WeakPolarHBondContact O-CB 3.21Å; M264-R667 PolarHBondContact O-NE 3.49Å; L265-R667 VanDerWaalsContact C-NH2 3.31Å; L265-R667 PolarHBondContact O-NH2 3.47Å; T266-R667 VanDerWaalsContact CA-NH2 3.33Å; T266-R667 VanDerWaalsContact O-CZ 3.29Å; T266-R667 PolarHBondContact O-NH1 3.46Å; T266-R667 PolarHBondContact O-NH2 2.86Å; G267-R667 VanDerWaalsContact CA-NE 3.28Å; T665-R667 PolarHBondContact O-N 2.8Å; T665-R667 VanDerWaalsContact O-N 3.11Å; R667-A669 VanDerWaalsContact C-N 3.34Å; R667-Y670 PolarHBondContact O-N 2.86Å; R667-N671 VanDerWaalsContact O-CG 3.22Å; R667-N671 PolarHBondContact O-N 3.22Å; R667-N671 PolarHBondContact O-OD1 3.44Å
668E97Very high96Very high100 Ų10056.6 Ų56.647%0.46730%0.304SS..Hα-helixtrans-65.2-40.1178.6-75162.1140.700111.3V664 T665 N671 A672V664-E668 HydrophobicContact CB-CB 3.91Å; V664-E668 HydrophobicContact CG2-CB 4.26Å; T665-E668 WeakPolarHBondContact CB-OE2 3.29Å; T665-E668 WeakPolarHBondContact CG2-OE2 3.49Å; T665-E668 PolarHBondContact N-OE2 3.35Å; T665-E668 PolarHBondContact O-N 2.93Å; T665-E668 VanDerWaalsContact OG1-CG 3.3Å; T665-E668 WeakPolarHBondContact OG1-CG 3.28Å; T665-E668 PolarHBondContact OG1-N 2.89Å; T665-E668 PolarHBondContact OG1-OE2 3.48Å; E668-N671 PolarHBondContact O-N 3.04Å; E668-A672 PolarHBondContact O-N 3.12Å
669A97.8Very high96.6Very high0 Ų058.8 Ų58.80%030%0.304CS..Hα-helixtrans-61.3-43.4172.500000111.9V664 T665 R667 A672 I673 G708V664-A669 HydrophobicContact CG2-CB 4.19Å; T665-A669 PolarHBondContact O-N 3.44Å; R667-A669 VanDerWaalsContact C-N 3.34Å; A669-A672 WeakPolarHBondContact O-CB 3.36Å; A669-A672 PolarHBondContact O-N 2.95Å; A669-I673 PolarHBondContact O-N 3.25Å; A669-G708 VanDerWaalsContact CB-N 3.35Å
670Y97.7Very high96.9Very high115 Ų11558.7 Ų58.745%0.45130%0.304SS..Hα-helixtrans-62.8-41.9173.7177.1-102.4000112.5P666 R667 A672 I673 V674P666-Y670 WeakPolarHBondContact O-CB 3.37Å; P666-Y670 PolarHBondContact O-N 3.15Å; R667-Y670 PolarHBondContact O-N 2.86Å; Y670-A672 VanDerWaalsContact C-N 3.27Å; Y670-A672 PolarHBondContact O-N 3.41Å; Y670-I673 WeakPolarHBondContact O-CB 3.4Å; Y670-I673 PolarHBondContact O-N 3.31Å; Y670-I673 VanDerWaalsContact O-N 3.08Å; Y670-V674 HydrophobicContact CD1-CG2 4.19Å; Y670-V674 HydrophobicContact CE1-CG2 3.7Å; Y670-V674 HydrophobicContact CE2-CG2 4.38Å; Y670-V674 PolarHBondContact O-N 3.39Å; Y670-V674 VanDerWaalsContact O-N 3.07Å
671N98Very high97Very high73 Ų7358.4 Ų58.439%0.3930%0.302SS..Hα-helixtrans-60.6-38.2175.2-70.8-14.7000111.4R667 E668 I673 V674 D675R667-N671 VanDerWaalsContact O-CG 3.22Å; R667-N671 PolarHBondContact O-N 3.22Å; R667-N671 PolarHBondContact O-OD1 3.44Å; E668-N671 PolarHBondContact O-N 3.04Å; N671-I673 VanDerWaalsContact C-N 3.29Å; N671-I673 PolarHBondContact O-N 3.46Å; N671-V674 PolarHBondContact O-N 3.26Å; N671-V674 VanDerWaalsContact O-N 3.13Å; N671-D675 WeakPolarHBondContact O-CB 3.49Å; N671-D675 PolarHBondContact O-N 2.88Å
672A98.2Very high97.2Very high9 Ų955.9 Ų55.97%0.07429%0.288CS..Hα-helixtrans-61.1-36.1174.400000112.6E668 A669 Y670 N676 N677 V678 V754E668-A672 PolarHBondContact O-N 3.12Å; A669-A672 WeakPolarHBondContact O-CB 3.36Å; A669-A672 PolarHBondContact O-N 2.95Å; Y670-A672 VanDerWaalsContact C-N 3.27Å; Y670-A672 PolarHBondContact O-N 3.41Å; A672-N676 PolarHBondContact O-N 3.26Å; A672-N677 HydrophobicContact CB-CB 4.31Å; A672-N677 WeakPolarHBondContact O-CA 3.36Å; A672-N677 PolarHBondContact O-N 3Å; A672-V678 HydrophobicContact CB-CG1 4.31Å; A672-V754 HydrophobicContact CB-CG1 4.09Å; A672-V754 HydrophobicContact CB-CG2 4.03Å
673I97.8Very high97.3Very high57 Ų5755.3 Ų55.329%0.29228%0.283SS..Hα-helixtrans-62.2-50.3171.5-61.7172000110A669 Y670 N671 D675 N676 V678 A692 M752A669-I673 PolarHBondContact O-N 3.25Å; Y670-I673 WeakPolarHBondContact O-CB 3.4Å; Y670-I673 PolarHBondContact O-N 3.31Å; Y670-I673 VanDerWaalsContact O-N 3.08Å; N671-I673 VanDerWaalsContact C-N 3.29Å; N671-I673 PolarHBondContact O-N 3.46Å; I673-D675 VanDerWaalsContact C-N 3.27Å; I673-D675 PolarHBondContact O-N 3.12Å; I673-N676 PolarHBondContact O-N 3.33Å; I673-V678 HydrophobicContact CB-CG1 4.48Å; I673-V678 HydrophobicContact CG1-CG1 3.92Å; I673-A692 HydrophobicContact CD1-CB 4.15Å; I673-A692 WeakPolarHBondContact CD1-O 3.4Å; I673-A692 HydrophobicContact CG1-CB 3.85Å; I673-M752 HydrophobicContact CD1-SD 4.29Å; I673-M752 HydrophobicContact CG1-SD 4.06Å; I673-M752 HydrophobicContact CG2-SD 4.45Å
674V97.9Very high97.3Very high90 Ų9056 Ų5655%0.54529%0.286SS..Hα-helixtrans-60.2-38.5-178.7176.40000111.7Y670 N671 N676Y670-V674 HydrophobicContact CD1-CG2 4.19Å; Y670-V674 HydrophobicContact CE1-CG2 3.7Å; Y670-V674 HydrophobicContact CE2-CG2 4.38Å; Y670-V674 PolarHBondContact O-N 3.39Å; Y670-V674 VanDerWaalsContact O-N 3.07Å; N671-V674 PolarHBondContact O-N 3.26Å; N671-V674 VanDerWaalsContact O-N 3.13Å; V674-N676 PolarHBondContact O-N 3.5Å
675D97.6Very high97.3Very high124 Ų12459.1 Ų59.166%0.66330%0.301SS*.THydrogen-bonded Turntrans-78.91.3178.3-69.2-21.3000113.4N671 I673 N677N671-D675 WeakPolarHBondContact O-CB 3.49Å; N671-D675 PolarHBondContact O-N 2.88Å; I673-D675 VanDerWaalsContact C-N 3.27Å; I673-D675 PolarHBondContact O-N 3.12Å; D675-N677 HydrophobicContact CB-CB 4.49Å; D675-N677 PolarHBondContact O-N 3.21Å
676N97.4Very high97.4Very high118 Ų11858.7 Ų58.763%0.63130%0.298SS*.THydrogen-bonded Turntrans55.530.4-173.6-165.232.3000113A672 I673 V674 V678 K755A672-N676 PolarHBondContact O-N 3.26Å; I673-N676 PolarHBondContact O-N 3.33Å; V674-N676 PolarHBondContact O-N 3.5Å; N676-V678 PolarHBondContact O-N 2.93Å; N676-K755 PolarHBondContact O-NZ 2.96Å
677N98.2Very high97.4Very high73 Ų7360.4 Ų60.439%0.3931%0.31SS..  trans-91.140.9174.6-167.440.6000111.8A672 D675 K755A672-N677 HydrophobicContact CB-CB 4.31Å; A672-N677 WeakPolarHBondContact O-CA 3.36Å; A672-N677 PolarHBondContact O-N 3Å; D675-N677 HydrophobicContact CB-CB 4.49Å; D675-N677 PolarHBondContact O-N 3.21Å; N677-K755 PolarHBondContact O-N 3.27Å
678V98.3Very high97.3Very high18 Ų1859.8 Ų59.811%0.10932%0.322CS..EExtended strand (participates in β ladder)trans-131.1156.9-177.7-66.30000111.2A672 I673 N676 A692 M752 C753 K755A672-V678 HydrophobicContact CB-CG1 4.31Å; I673-V678 HydrophobicContact CB-CG1 4.48Å; I673-V678 HydrophobicContact CG1-CG1 3.92Å; N676-V678 PolarHBondContact O-N 2.93Å; V678-A692 HydrophobicContact CB-CB 4.46Å; V678-A692 HydrophobicContact CG1-CB 3.58Å; V678-M752 HydrophobicContact CB-CG 3.84Å; V678-M752 HydrophobicContact CB-SD 4.22Å; V678-M752 HydrophobicContact CG1-CG 4.34Å; V678-M752 HydrophobicContact CG2-CG 4.06Å; V678-M752 HydrophobicContact CG2-SD 3.87Å; V678-C753 CarbonylContact C-O 3.6Å; V678-C753 WeakPolarHBondContact CA-O 3.3Å; V678-C753 WeakPolarHBondContact CB-O 3.41Å; V678-K755 WeakPolarHBondContact O-CE 2.85Å
679E97.9Very high97.4Very high80 Ų8056.7 Ų56.737%0.37431%0.305SS..EExtended strand (participates in β ladder)trans-142.6151.1172.361.4179.1171.600110.4V681 R689 C753 K755E679-V681 HydrophobicContact CG-CG2 3.85Å; E679-R689 IonicContact OE1-CZ 3.36Å; E679-R689 IonicContact OE1-NH1 2.96Å; E679-R689 PolarHBondContact OE1-NH1 3.24Å; E679-R689 IonicContact OE1-NH2 3.48Å; E679-R689 PolarHBondContact OE1-NH2 3.47Å; E679-C753 PolarHBondContact N-O 3.37Å; E679-C753 PolarHBondContact O-N 3.01Å; E679-K755 HydrophobicContact CB-CG 4.31Å; E679-K755 HydrophobicContact CG-CG 4.17Å
680L97.6Very high97.4Very high72 Ų7258.6 Ų58.638%0.37732%0.315SS..EExtended strand (participates in β ladder)trans-78.7124.6170.5-73172.6000109.1E743 I745 H750 M752L680-E743 VanDerWaalsContact CD1-OE2 3.24Å; L680-E743 WeakPolarHBondContact CD1-OE2 3.3Å; L680-I745 HydrophobicContact CD1-CD1 4.41Å; L680-H750 HydrophobicContact CB-CB 4.44Å; L680-M752 HydrophobicContact CD2-CB 4.19Å
681V98Very high97.4Very high8 Ų853.1 Ų53.15%0.04829%0.294CS..EExtended strand (participates in β ladder)trans-117.3123.4-176.5-175.60000108.8E679 N685 L686 R689 H750 V751 C753E679-V681 HydrophobicContact CG-CG2 3.85Å; V681-N685 VanDerWaalsContact CG1-C 3.48Å; V681-N685 HydrophobicContact CG1-CB 3.58Å; V681-N685 WeakPolarHBondContact CG1-O 3.29Å; V681-L686 HydrophobicContact CB-CD2 4Å; V681-L686 HydrophobicContact CG1-CD2 4.03Å; V681-R689 HydrophobicContact CG1-CG 4.36Å; V681-R689 VanDerWaalsContact CG2-NH1 3.25Å; V681-H750 CarbonylContact O-C 3.59Å; V681-H750 VanDerWaalsContact O-CA 3.28Å; V681-H750 WeakPolarHBondContact O-CA 3.38Å; V681-V751 PolarHBondContact N-O 2.81Å; V681-V751 PolarHBondContact O-N 3.19Å; V681-C753 HydrophobicContact CB-CB 4.45Å; V681-C753 HydrophobicContact CG2-CB 3.66Å
682S97.3Very high97.4Very high22 Ų2249.6 Ų49.615%0.15428%0.275CS..EExtended strand (participates in β ladder)trans-59.5149.6174.362.10000111.2E684 N685 L686 Y749 H750S682-E684 PolarHBondContact O-N 3.28Å; S682-N685 PolarHBondContact O-N 2.86Å; S682-N685 PolarHBondContact OG-ND2 2.88Å; S682-L686 PolarHBondContact O-N 3.28Å; S682-Y749 CarbonylContact C-O 3.48Å; S682-H750 VanDerWaalsContact CA-CD2 3.49Å; S682-H750 WeakPolarHBondContact CA-CD2 3.49Å; S682-H750 PolarHBondContact N-CD2 2.78Å
683I95.7Very high97.3Very high1 Ų151 Ų511%0.00528%0.281CS..G310 helixtrans-48.5-35.9-179-163167.1000114.4N685 L686 L722 R723 I748 Y749I683-N685 VanDerWaalsContact C-N 3.26Å; I683-N685 PolarHBondContact O-N 2.84Å; I683-L686 HydrophobicContact CB-CD1 4.41Å; I683-L686 HydrophobicContact CG1-CD1 4.08Å; I683-L686 PolarHBondContact O-N 3.39Å; I683-L722 HydrophobicContact CD1-CB 3.73Å; I683-L722 HydrophobicContact CG1-CB 4.47Å; I683-R723 HydrophobicContact CD1-CB 4.24Å; I683-R723 HydrophobicContact CD1-CG 3.61Å; I683-R723 HydrophobicContact CG1-CG 3.99Å; I683-I748 HydrophobicContact CG2-CG2 4.18Å; I683-Y749 PolarHBondContact N-O 3.41Å
684E94.7Very high97.2Very high107 Ų10748.9 Ų48.950%0.527%0.271SS..G310 helixtrans-68.1-22.8179.5-62.5-52.4146.100114.5S682 R723S682-E684 PolarHBondContact O-N 3.28Å; E684-R723 IonicContact OE1-NE 3.38Å; E684-R723 IonicContact OE2-CZ 3.3Å; E684-R723 IonicContact OE2-NE 3.96Å; E684-R723 IonicContact OE2-NH2 3.61Å; E684-R723 PolarHBondContact OE2-NH2 3.43Å
685N96.7Very high97.1Very high103 Ų10344.6 Ų44.655%0.55125%0.245SC*.G310 helixtrans-108.15-176.2-66.3-49.6000112.6V681 S682 I683 P687 R689V681-N685 VanDerWaalsContact CG1-C 3.48Å; V681-N685 HydrophobicContact CG1-CB 3.58Å; V681-N685 WeakPolarHBondContact CG1-O 3.29Å; S682-N685 PolarHBondContact O-N 2.86Å; S682-N685 PolarHBondContact OG-ND2 2.88Å; I683-N685 VanDerWaalsContact C-N 3.26Å; I683-N685 PolarHBondContact O-N 2.84Å; N685-P687 VanDerWaalsContact C-CD 3.41Å; N685-R689 WeakPolarHBondContact O-CG 3.37Å
686L97Very high97Very high1 Ų138.9 Ų38.91%0.00522%0.215CC..  trans-64.9-33.2174.8-65.7178.2000114.7V681 S682 I683 G688 R689 F711 V719 L722 V751V681-L686 HydrophobicContact CB-CD2 4Å; V681-L686 HydrophobicContact CG1-CD2 4.03Å; S682-L686 PolarHBondContact O-N 3.28Å; I683-L686 HydrophobicContact CB-CD1 4.41Å; I683-L686 HydrophobicContact CG1-CD1 4.08Å; I683-L686 PolarHBondContact O-N 3.39Å; L686-G688 PolarHBondContact O-N 2.86Å; L686-G688 VanDerWaalsContact O-N 3.15Å; L686-R689 WeakPolarHBondContact O-CB 3.4Å; L686-R689 VanDerWaalsContact O-CG 3.29Å; L686-R689 WeakPolarHBondContact O-CG 3.24Å; L686-R689 PolarHBondContact O-N 3.4Å; L686-F711 HydrophobicContact CB-CB 4.3Å; L686-F711 HydrophobicContact CB-CD1 4.19Å; L686-F711 HydrophobicContact CB-CD2 4.19Å; L686-F711 HydrophobicContact CB-CG 3.96Å; L686-F711 HydrophobicContact CD1-CD1 4.19Å; L686-F711 HydrophobicContact CD1-CE1 3.88Å; L686-F711 HydrophobicContact CD1-CZ 4.06Å; L686-F711 HydrophobicContact CD2-CD2 4.17Å; L686-F711 HydrophobicContact CD2-CE2 3.87Å; L686-F711 HydrophobicContact CD2-CZ 4.12Å; L686-F711 VanDerWaalsContact O-CB 3.27Å; L686-F711 WeakPolarHBondContact O-CB 3.42Å; L686-V719 HydrophobicContact CB-CG2 4.29Å; L686-L722 HydrophobicContact CD1-CD1 4.15Å; L686-V751 HydrophobicContact CD1-CG2 3.94Å; L686-V751 HydrophobicContact CD2-CB 3.82Å; L686-V751 HydrophobicContact CD2-CG2 4.08Å
687P96.8Very high96.8Very high40 Ų4033.7 Ų33.726%0.2619%0.188SC..THydrogen-bonded Turntrans-51.3124.7179.7-3238.8000113.1N685 R689 G712 K714N685-P687 VanDerWaalsContact C-CD 3.41Å; P687-R689 VanDerWaalsContact C-N 3.33Å; P687-G712 CarbonylContact C-O 3.56Å; P687-G712 VanDerWaalsContact CA-O 3.29Å; P687-G712 WeakPolarHBondContact CA-O 3.37Å; P687-K714 HydrophobicContact CG-CB 4.26Å
688G96.1Very high96.1Very high45 Ų4534.7 Ų34.746%0.46419%0.186SC..THydrogen-bonded Turntrans85.3-4.6-179.600000114.8L686 N710 G712L686-G688 PolarHBondContact O-N 2.86Å; L686-G688 VanDerWaalsContact O-N 3.15Å; G688-N710 WeakPolarHBondContact CA-OD1 3.41Å; G688-N710 PolarHBondContact O-ND2 3.47Å; G688-G712 PolarHBondContact N-O 2.85Å
689R97.9Very high94.8Very high34 Ų3436.1 Ų36.113%0.12820%0.196CC..PPolyproline II helixtrans-85.5151.3-178.1-55.7-57-56.8-90.1-5.1111.8E679 V681 N685 L686 P687 N710 F711 C753 V754E679-R689 IonicContact OE1-CZ 3.36Å; E679-R689 IonicContact OE1-NH1 2.96Å; E679-R689 PolarHBondContact OE1-NH1 3.24Å; E679-R689 IonicContact OE1-NH2 3.48Å; E679-R689 PolarHBondContact OE1-NH2 3.47Å; V681-R689 HydrophobicContact CG1-CG 4.36Å; V681-R689 VanDerWaalsContact CG2-NH1 3.25Å; N685-R689 WeakPolarHBondContact O-CG 3.37Å; L686-R689 WeakPolarHBondContact O-CB 3.4Å; L686-R689 VanDerWaalsContact O-CG 3.29Å; L686-R689 WeakPolarHBondContact O-CG 3.24Å; L686-R689 PolarHBondContact O-N 3.4Å; P687-R689 VanDerWaalsContact C-N 3.33Å; R689-N710 CarbonylContact O-C 3.39Å; R689-N710 WeakPolarHBondContact O-CA 3.47Å; R689-F711 HydrophobicContact CB-CD2 4.39Å; R689-F711 WeakPolarHBondContact O-CD2 3.45Å; R689-F711 PolarHBondContact O-N 2.82Å; R689-C753 HydrophobicContact CB-CB 4.14Å; R689-V754 PolarHBondContact NH2-O 2.94Å
690I97.9Very high93.6Very high40 Ų4033.1 Ų33.121%0.20518%0.184CC..BIsolated β-bridgetrans-96.8123.9174.5-59.1170.6000108.1E663 V664 E709 C753 V754E663-I690 HydrophobicContact CB-CD1 3.79Å; E663-I690 HydrophobicContact CB-CG1 4.13Å; E663-I690 HydrophobicContact CG-CD1 4.21Å; E663-I690 HydrophobicContact CG-CG1 4.21Å; V664-I690 HydrophobicContact CG2-CG2 4.07Å; I690-E709 WeakPolarHBondContact CA-O 3.38Å; I690-C753 CarbonylContact O-C 3.17Å; I690-C753 WeakPolarHBondContact O-CA 3.22Å; I690-C753 WeakPolarHBondContact O-CB 3.22Å; I690-V754 HydrophobicContact CB-CB 4.31Å; I690-V754 HydrophobicContact CB-CG2 4.37Å; I690-V754 HydrophobicContact CG2-CG2 4.08Å; I690-V754 PolarHBondContact O-N 2.84Å
691A98Very high92.6Very high0 Ų029.7 Ų29.70%017%0.166CC..BIsolated β-bridgetrans-68.7134.4176.400000111.4L705 G708 E709 F711A691-L705 HydrophobicContact CB-CD2 3.2Å; A691-G708 PolarHBondContact O-N 3.46Å; A691-E709 PolarHBondContact N-O 3.31Å; A691-F711 HydrophobicContact CB-CE2 3.79Å; A691-F711 HydrophobicContact CB-CZ 4.32Å
692A97.8Very high92.2Very high0 Ų029.7 Ų29.70%017%0.166CC..SBendtrans-84.6-29.8176.600000111.8I673 V678 S707 M752 V754I673-A692 HydrophobicContact CD1-CB 4.15Å; I673-A692 WeakPolarHBondContact CD1-O 3.4Å; I673-A692 HydrophobicContact CG1-CB 3.85Å; V678-A692 HydrophobicContact CB-CB 4.46Å; V678-A692 HydrophobicContact CG1-CB 3.58Å; A692-S707 VanDerWaalsContact O-CB 3.25Å; A692-S707 WeakPolarHBondContact O-CB 3.47Å; A692-M752 HydrophobicContact CB-CB 4.41Å; A692-M752 HydrophobicContact CB-CG 3.96Å; A692-M752 WeakPolarHBondContact CB-O 3.42Å; A692-M752 HydrophobicContact CB-SD 4.44Å; A692-M752 PolarHBondContact N-O 3.37Å; A692-V754 HydrophobicContact CB-CG2 4.27Å
693N95.7Very high92Very high39 Ų3928.7 Ų28.721%0.20916%0.159CC..SBendtrans-125.6161.2177.261.3-25.7000110.7G741 M752N693-G741 VanDerWaalsContact ND2-CA 3.34Å; N693-G741 WeakPolarHBondContact ND2-CA 3.41Å; N693-G741 PolarHBondContact ND2-O 2.81Å; N693-M752 PolarHBondContact OD1-O 2.76Å
694S96.6Very high91.9Very high11 Ų1128.8 Ų28.88%0.07716%0.159CC..  trans-62.5144.9171.2-970000112.3E260 L705 G741E260-S694 PolarHBondContact OE1-OG 2.93Å; E260-S694 WeakPolarHBondContact OE2-CB 3.22Å; E260-S694 PolarHBondContact OE2-OG 3.49Å; S694-L705 CarbonylContact C-O 3.57Å; S694-L705 VanDerWaalsContact CA-O 3.31Å; S694-L705 WeakPolarHBondContact CA-O 3.39Å; S694-L705 PolarHBondContact OG-O 3.06Å; S694-G741 WeakPolarHBondContact O-CA 2.92Å
695V96.8Very high92Very high0 Ų023.7 Ų23.70%014%0.135CC..BIsolated β-bridgetrans-109.7117.8169.7-176.70000109.2M704 L705 F711 L722 T739 T742 V751V695-M704 HydrophobicContact CB-CE 4.38Å; V695-M704 HydrophobicContact CG1-CE 3.98Å; V695-M704 PolarHBondContact O-N 3.48Å; V695-L705 HydrophobicContact CB-CB 4.33Å; V695-L705 PolarHBondContact N-O 3.34Å; V695-L705 PolarHBondContact O-N 2.69Å; V695-F711 HydrophobicContact CG2-CZ 4.05Å; V695-L722 HydrophobicContact CG1-CD1 4.26Å; V695-L722 HydrophobicContact CG1-CD2 3.81Å; V695-T739 HydrophobicContact CG1-CG2 4.08Å; V695-T742 HydrophobicContact CG1-CG2 4.05Å; V695-V751 HydrophobicContact CG2-CG1 3.69Å; V695-V751 HydrophobicContact CG2-CG2 4.32Å
696I95.4Very high92Very high4 Ų419 Ų192%0.02111%0.11CC..EExtended strand (participates in β ladder)trans-132.196.9-167.3-42.7-178.4000110.7K257 Y698 P703 T739 E740K257-I696 HydrophobicContact CB-CD1 3.88Å; K257-I696 HydrophobicContact CD-CD1 4.01Å; I696-Y698 PolarHBondContact O-N 3.02Å; I696-P703 HydrophobicContact CD1-CG 4.07Å; I696-P703 HydrophobicContact CG1-CB 4.25Å; I696-P703 HydrophobicContact CG1-CG 4.13Å; I696-T739 CarbonylContact O-C 3.23Å; I696-T739 WeakPolarHBondContact O-CA 3.08Å; I696-E740 HydrophobicContact CB-CB 4.09Å; I696-E740 PolarHBondContact N-O 2.88Å; I696-E740 PolarHBondContact O-N 3.43Å
697P92Very high92Very high10 Ų1019 Ų197%0.06511%0.11CC..EExtended strand (participates in β ladder)trans-58124.8162.7-23.736000110M704 Y721 L725 T739P697-M704 HydrophobicContact CG-CB 4.44Å; P697-Y721 HydrophobicContact CB-CE1 4.18Å; P697-Y721 HydrophobicContact CG-CD1 4.43Å; P697-Y721 HydrophobicContact CG-CE1 3.78Å; P697-L725 HydrophobicContact CB-CD1 4.15Å; P697-L725 HydrophobicContact CG-CD1 4.01Å; P697-T739 HydrophobicContact CG-CG2 4.32Å
698Y83.8Confident92Very high93 Ų9317 Ų1737%0.36510%0.097SC..EExtended strand (participates in β ladder)trans-122.8142.6-169.2-165.7-91.8000112.1I696 E738I696-Y698 PolarHBondContact O-N 3.02Å; Y698-E738 PolarHBondContact N-O 2.78Å
699P70.9Confident92Very high48 Ų4815 Ų1531%0.3128%0.076SC..THydrogen-bonded Turncis-68.8159.5-8.228.4-34.6000113.1R573R573-P699 HydrophobicContact CB-CG 4.27Å; R573-P699 HydrophobicContact CG-CG 4.29Å
700P73.4Confident92Very high17 Ų1714.5 Ų14.511%0.118%0.076CC..THydrogen-bonded Turncis-112.59.821.940.3-37.3000117.7I283 Y324 I702I283-P700 HydrophobicContact CD1-CG 4.28Å; Y324-P700 HydrophobicContact CD1-CB 4Å; Y324-P700 HydrophobicContact CD2-CB 3.26Å; Y324-P700 HydrophobicContact CD2-CG 4.41Å; Y324-P700 HydrophobicContact CE1-CB 4.27Å; Y324-P700 HydrophobicContact CE2-CB 3.53Å; Y324-P700 HydrophobicContact CG-CB 3.5Å; Y324-P700 HydrophobicContact CG-CG 4.34Å; P700-I702 HydrophobicContact CB-CD1 4.35Å; P700-I702 HydrophobicContact CG-CB 4.2Å; P700-I702 HydrophobicContact CG-CD1 3.41Å; P700-I702 VanDerWaalsContact CG-CD1 3.41Å; P700-I702 HydrophobicContact CG-CG1 3.79Å
701G76Confident91.9Very high0 Ų012.6 Ų12.60%07%0.066CC..  trans93.325.5-176.400000114.2K257K257-G701 PolarHBondContact N-O 3.28Å
702I89.4Confident91.8Very high9 Ų914 Ų145%0.0468%0.081CC..  trans-107.5114.1-178.6-65.8167000108.8N254 I283 Y656 P700 M704N254-I702 WeakPolarHBondContact OD1-CD1 3.28Å; I283-I702 HydrophobicContact CD1-CD1 3.62Å; Y656-I702 HydrophobicContact CE1-CG2 4.2Å; Y656-I702 PolarHBondContact OH-O 3.01Å; P700-I702 HydrophobicContact CB-CD1 4.35Å; P700-I702 HydrophobicContact CG-CB 4.2Å; P700-I702 HydrophobicContact CG-CD1 3.41Å; P700-I702 VanDerWaalsContact CG-CD1 3.41Å; P700-I702 HydrophobicContact CG-CG1 3.79Å; I702-M704 PolarHBondContact O-N 3.34Å
703P93.3Very high91.7Very high1 Ų118.6 Ų18.61%0.00611%0.105CC..  trans-59.5128.1-175.5-26.136.4000112.6C255 I696 L706C255-P703 WeakPolarHBondContact O-CD 3.39Å; I696-P703 HydrophobicContact CD1-CG 4.07Å; I696-P703 HydrophobicContact CG1-CB 4.25Å; I696-P703 HydrophobicContact CG1-CG 4.13Å; P703-L706 HydrophobicContact CB-CD2 3.49Å; P703-L706 VanDerWaalsContact CB-CD2 3.49Å; P703-L706 HydrophobicContact CB-CG 4.11Å; P703-L706 HydrophobicContact CG-CD2 3.54Å
704M94.7Very high91.5Very high2 Ų223.8 Ų23.81%0.0113%0.126CC..SBendtrans-70.7-45165.3179.3-167.461.200109.1R253 A655 Y656 V695 P697 I702 Q718 Y721 L722R253-M704 PolarHBondContact NH2-O 2.92Å; A655-M704 HydrophobicContact CB-CG 4.12Å; A655-M704 HydrophobicContact CB-SD 3.96Å; Y656-M704 HydrophobicContact CE1-CB 4.26Å; Y656-M704 HydrophobicContact CE2-CB 4.35Å; Y656-M704 HydrophobicContact CE2-CG 4.46Å; V695-M704 HydrophobicContact CB-CE 4.38Å; V695-M704 HydrophobicContact CG1-CE 3.98Å; V695-M704 PolarHBondContact O-N 3.48Å; P697-M704 HydrophobicContact CG-CB 4.44Å; I702-M704 PolarHBondContact O-N 3.34Å; M704-Q718 HydrophobicContact CE-CB 3.91Å; M704-Q718 HydrophobicContact CE-CG 4.34Å; M704-Q718 HydrophobicContact CG-CG 4.03Å; M704-Q718 HydrophobicContact SD-CB 4.01Å; M704-Q718 HydrophobicContact SD-CG 4.12Å; M704-Y721 HydrophobicContact SD-CD1 3.69Å; M704-L722 HydrophobicContact CE-CD1 3.93Å; M704-L722 HydrophobicContact CE-CD2 4.04Å; M704-L722 HydrophobicContact CE-CG 3.75Å
705L95.3Very high91.3Very high0 Ų029 Ų290%015%0.153CC..BIsolated β-bridgetrans-129.7129178.2-164.3108.8000108.4P660 A691 S694 V695 E709 F711 Q718P660-L705 HydrophobicContact CB-CD1 3.73Å; P660-L705 HydrophobicContact CG-CD1 3.62Å; P660-L705 HydrophobicContact CG-CG 4.45Å; A691-L705 HydrophobicContact CB-CD2 3.2Å; S694-L705 CarbonylContact C-O 3.57Å; S694-L705 VanDerWaalsContact CA-O 3.31Å; S694-L705 WeakPolarHBondContact CA-O 3.39Å; S694-L705 PolarHBondContact OG-O 3.06Å; V695-L705 HydrophobicContact CB-CB 4.33Å; V695-L705 PolarHBondContact N-O 3.34Å; V695-L705 PolarHBondContact O-N 2.69Å; L705-E709 HydrophobicContact CD1-CB 4.13Å; L705-E709 HydrophobicContact CD2-CB 4.34Å; L705-E709 HydrophobicContact CG-CB 3.9Å; L705-F711 HydrophobicContact CD1-CD1 4.46Å; L705-F711 HydrophobicContact CD2-CD1 4.38Å; L705-F711 HydrophobicContact CD2-CD2 4.29Å; L705-F711 HydrophobicContact CD2-CE1 3.99Å; L705-F711 HydrophobicContact CD2-CE2 3.9Å; L705-F711 HydrophobicContact CD2-CZ 3.74Å; L705-Q718 HydrophobicContact CD1-CB 4.42Å; L705-Q718 HydrophobicContact CD1-CG 4.13Å
706L96.3Very high91.2Very high4 Ų429.3 Ų29.32%0.02116%0.155CC..  trans-87.8161.4176.8-68.4171.3000111.1E260 Y272 P703 G708 E709E260-L706 HydrophobicContact CB-CD2 3.86Å; E260-L706 HydrophobicContact CG-CD2 3.8Å; Y272-L706 HydrophobicContact CE1-CD1 3.61Å; Y272-L706 HydrophobicContact CE2-CD1 4.29Å; Y272-L706 WeakPolarHBondContact OH-CD1 3.33Å; P703-L706 HydrophobicContact CB-CD2 3.49Å; P703-L706 VanDerWaalsContact CB-CD2 3.49Å; P703-L706 HydrophobicContact CB-CG 4.11Å; P703-L706 HydrophobicContact CG-CD2 3.54Å; L706-G708 PolarHBondContact O-N 3.02Å; L706-E709 HydrophobicContact CB-CG 4.34Å; L706-E709 PolarHBondContact N-OE2 2.84Å; L706-E709 WeakPolarHBondContact O-CB 3.33Å; L706-E709 PolarHBondContact O-N 2.93Å
707S97.1Very high91.2Very high1 Ų131.2 Ų31.21%0.00717%0.168CC..THydrogen-bonded Turntrans-61.2136.9171.670.90000111.4E260 M264 P666 A692E260-S707 WeakPolarHBondContact OE1-CB 3.24Å; E260-S707 PolarHBondContact OE1-N 3.25Å; E260-S707 PolarHBondContact OE1-OG 3.49Å; M264-S707 WeakPolarHBondContact CE-OG 3.49Å; P666-S707 VanDerWaalsContact CA-OG 3.29Å; P666-S707 WeakPolarHBondContact CA-OG 3.42Å; P666-S707 WeakPolarHBondContact CB-OG 3.29Å; P666-S707 PolarHBondContact O-OG 2.86Å; A692-S707 VanDerWaalsContact O-CB 3.25Å; A692-S707 WeakPolarHBondContact O-CB 3.47Å
708G97.2Very high91.4Very high0 Ų031.3 Ų31.30%017%0.167CC..THydrogen-bonded Turntrans89.5-2.7-17700000115.1E663 V664 A669 A691 L706E663-G708 PolarHBondContact N-O 2.97Å; V664-G708 VanDerWaalsContact CG2-CA 3.45Å; V664-G708 PolarHBondContact N-O 3.21Å; V664-G708 VanDerWaalsContact N-O 3.17Å; V664-G708 WeakPolarHBondContact O-CA 3.5Å; A669-G708 VanDerWaalsContact CB-N 3.35Å; A691-G708 PolarHBondContact O-N 3.46Å; L706-G708 PolarHBondContact O-N 3.02Å
709E97.3Very high91.9Very high3 Ų326.9 Ų26.91%0.01415%0.15CC..BIsolated β-bridgetrans-89.8147.5175.2-69.5179.116500113.1R253 P660 V661 A662 I690 A691 L705 L706R253-E709 IonicContact CZ-OE1 3.02Å; R253-E709 IonicContact CZ-OE2 3.96Å; R253-E709 IonicContact NH1-OE1 3.56Å; R253-E709 PolarHBondContact NH1-OE1 2.86Å; R253-E709 IonicContact NH1-OE2 2.61Å; R253-E709 VanDerWaalsContact NH2-CD 3.33Å; R253-E709 IonicContact NH2-OE1 2.84Å; R253-E709 PolarHBondContact NH2-OE1 2.61Å; R253-E709 IonicContact NH2-OE2 3.12Å; R253-E709 PolarHBondContact NH2-OE2 3.25Å; P660-E709 HydrophobicContact CB-CB 3.9Å; P660-E709 HydrophobicContact CB-CG 4.25Å; V661-E709 CarbonylContact O-C 3.51Å; V661-E709 WeakPolarHBondContact O-CA 3.45Å; A662-E709 HydrophobicContact CB-CG 4.09Å; I690-E709 WeakPolarHBondContact CA-O 3.38Å; A691-E709 PolarHBondContact N-O 3.31Å; L705-E709 HydrophobicContact CD1-CB 4.13Å; L705-E709 HydrophobicContact CD2-CB 4.34Å; L705-E709 HydrophobicContact CG-CB 3.9Å; L706-E709 HydrophobicContact CB-CG 4.34Å; L706-E709 PolarHBondContact N-OE2 2.84Å; L706-E709 WeakPolarHBondContact O-CB 3.33Å; L706-E709 PolarHBondContact O-N 2.93Å
710N96.6Very high93.1Very high23 Ų2326.4 Ų26.412%0.12315%0.148CC..BIsolated β-bridgetrans-86.2137.6177.5-162.2-69.3000111.3V661 E663 G688 R689 G712V661-N710 PolarHBondContact O-N 3.09Å; E663-N710 HydrophobicContact CG-CB 3.88Å; G688-N710 WeakPolarHBondContact CA-OD1 3.41Å; G688-N710 PolarHBondContact O-ND2 3.47Å; R689-N710 CarbonylContact O-C 3.39Å; R689-N710 WeakPolarHBondContact O-CA 3.47Å; N710-G712 PolarHBondContact O-N 2.69Å; N710-G712 VanDerWaalsContact O-N 3.15Å; N710-G712 PolarHBondContact OD1-N 2.95Å
711F96.5Very high94.1Very high0 Ų026.5 Ų26.50%015%0.146CC..  trans-66.4-7.5174.9-84.2-78.5000114.6L686 R689 A691 V695 L705 S716 V719 L722 V751L686-F711 HydrophobicContact CB-CB 4.3Å; L686-F711 HydrophobicContact CB-CD1 4.19Å; L686-F711 HydrophobicContact CB-CD2 4.19Å; L686-F711 HydrophobicContact CB-CG 3.96Å; L686-F711 HydrophobicContact CD1-CD1 4.19Å; L686-F711 HydrophobicContact CD1-CE1 3.88Å; L686-F711 HydrophobicContact CD1-CZ 4.06Å; L686-F711 HydrophobicContact CD2-CD2 4.17Å; L686-F711 HydrophobicContact CD2-CE2 3.87Å; L686-F711 HydrophobicContact CD2-CZ 4.12Å; L686-F711 VanDerWaalsContact O-CB 3.27Å; L686-F711 WeakPolarHBondContact O-CB 3.42Å; R689-F711 HydrophobicContact CB-CD2 4.39Å; R689-F711 WeakPolarHBondContact O-CD2 3.45Å; R689-F711 PolarHBondContact O-N 2.82Å; A691-F711 HydrophobicContact CB-CE2 3.79Å; A691-F711 HydrophobicContact CB-CZ 4.32Å; V695-F711 HydrophobicContact CG2-CZ 4.05Å; L705-F711 HydrophobicContact CD1-CD1 4.46Å; L705-F711 HydrophobicContact CD2-CD1 4.38Å; L705-F711 HydrophobicContact CD2-CD2 4.29Å; L705-F711 HydrophobicContact CD2-CE1 3.99Å; L705-F711 HydrophobicContact CD2-CE2 3.9Å; L705-F711 HydrophobicContact CD2-CZ 3.74Å; F711-S716 WeakPolarHBondContact O-CB 3.41Å; F711-S716 PolarHBondContact O-OG 3.39Å; F711-V719 HydrophobicContact CB-CG2 4.07Å; F711-V719 HydrophobicContact CD1-CG2 3.89Å; F711-V719 HydrophobicContact CG-CG2 4.39Å; F711-L722 HydrophobicContact CE1-CD1 3.87Å; F711-V751 HydrophobicContact CE2-CG1 4.22Å; F711-V751 HydrophobicContact CZ-CB 4.2Å; F711-V751 HydrophobicContact CZ-CG1 3.94Å; F711-V751 HydrophobicContact CZ-CG2 4.13Å
712G95.5Very high95Very high30 Ų3026.6 Ų26.631%0.30915%0.146SC..  trans74-162.9-177.900000112.3P687 G688 N710P687-G712 CarbonylContact C-O 3.56Å; P687-G712 VanDerWaalsContact CA-O 3.29Å; P687-G712 WeakPolarHBondContact CA-O 3.37Å; G688-G712 PolarHBondContact N-O 2.85Å; N710-G712 PolarHBondContact O-N 2.69Å; N710-G712 VanDerWaalsContact O-N 3.15Å; N710-G712 PolarHBondContact OD1-N 2.95Å
713D95.4Very high95.3Very high96 Ų9629.4 Ų29.451%0.51316%0.156SC..SBendtrans-84.1-172.9178.672.818.6000112.6N715 S716D713-N715 PolarHBondContact O-N 3.22Å; D713-N715 VanDerWaalsContact O-N 3.13Å; D713-N715 WeakPolarHBondContact OD1-CA 3.36Å; D713-N715 WeakPolarHBondContact OD1-CB 3.38Å; D713-N715 PolarHBondContact OD1-N 3.26Å; D713-S716 WeakPolarHBondContact O-CB 3.47Å; D713-S716 PolarHBondContact O-N 3.39Å; D713-S716 PolarHBondContact OD1-N 3.04Å
714K92.5Very high95.3Very high148 Ų14829.4 Ų29.464%0.64316%0.156SC*.THydrogen-bonded Turntrans-62.8-16.9-18065.6176.5-178.5176.40114.8P687 R723P687-K714 HydrophobicContact CG-CB 4.26Å; K714-R723 PolarHBondContact O-NH1 3.17Å
715N92.3Very high95.3Very high120 Ų12029.5 Ų29.564%0.64216%0.157SC*.THydrogen-bonded Turntrans-100.78.3177.6-51.9-45.6000111.7D713D713-N715 PolarHBondContact O-N 3.22Å; D713-N715 VanDerWaalsContact O-N 3.13Å; D713-N715 WeakPolarHBondContact OD1-CA 3.36Å; D713-N715 WeakPolarHBondContact OD1-CB 3.38Å; D713-N715 PolarHBondContact OD1-N 3.26Å
716S94.8Very high95.3Very high6 Ų630.7 Ų30.74%0.04216%0.163CC..  trans-52.9129.9176.11680000111.9F711 D713 Q718 V719 S720F711-S716 WeakPolarHBondContact O-CB 3.41Å; F711-S716 PolarHBondContact O-OG 3.39Å; D713-S716 WeakPolarHBondContact O-CB 3.47Å; D713-S716 PolarHBondContact O-N 3.39Å; D713-S716 PolarHBondContact OD1-N 3.04Å; S716-Q718 PolarHBondContact O-N 3.43Å; S716-Q718 PolarHBondContact OG-N 3.01Å; S716-Q718 PolarHBondContact OG-OE1 2.91Å; S716-V719 PolarHBondContact O-N 2.85Å; S716-S720 WeakPolarHBondContact O-CB 3.34Å; S716-S720 PolarHBondContact O-N 3.03Å
717P95.4Very high95.3Very high45 Ų4531.9 Ų31.929%0.29217%0.171SC..Hα-helixtrans-54.2-38.4173.6-29.737.8000113.2E654 A655 S720 Y721E654-P717 HydrophobicContact CB-CB 4.1Å; A655-P717 HydrophobicContact CB-CB 4.36Å; P717-S720 PolarHBondContact O-N 2.98Å; P717-Y721 PolarHBondContact O-N 2.81Å
718Q95.2Very high95.3Very high12 Ų1232.3 Ų32.36%0.05617%0.173CC..Hα-helixtrans-66.9-43.5-179.1-66.375.920.100111.6A655 P660 M704 L705 S716 L722A655-Q718 PolarHBondContact O-NE2 3Å; P660-Q718 HydrophobicContact CG-CG 4.22Å; M704-Q718 HydrophobicContact CE-CB 3.91Å; M704-Q718 HydrophobicContact CE-CG 4.34Å; M704-Q718 HydrophobicContact CG-CG 4.03Å; M704-Q718 HydrophobicContact SD-CB 4.01Å; M704-Q718 HydrophobicContact SD-CG 4.12Å; L705-Q718 HydrophobicContact CD1-CB 4.42Å; L705-Q718 HydrophobicContact CD1-CG 4.13Å; S716-Q718 PolarHBondContact O-N 3.43Å; S716-Q718 PolarHBondContact OG-N 3.01Å; S716-Q718 PolarHBondContact OG-OE1 2.91Å; Q718-L722 WeakPolarHBondContact O-CG 3.19Å; Q718-L722 PolarHBondContact O-N 2.77Å; Q718-L722 VanDerWaalsContact O-N 3.11Å
719V95.4Very high95.1Very high0 Ų033.1 Ų33.10%018%0.177CC..Hα-helixtrans-67.4-38.8175.4178.70000110.6L686 F711 S716 L722 R723L686-V719 HydrophobicContact CB-CG2 4.29Å; F711-V719 HydrophobicContact CB-CG2 4.07Å; F711-V719 HydrophobicContact CD1-CG2 3.89Å; F711-V719 HydrophobicContact CG-CG2 4.39Å; S716-V719 PolarHBondContact O-N 2.85Å; V719-L722 PolarHBondContact O-N 2.77Å; V719-R723 WeakPolarHBondContact O-CG 3.41Å; V719-R723 PolarHBondContact O-N 2.81Å
720S95Very high95Very high38 Ų3837.9 Ų37.927%0.26620%0.199SC..Hα-helixtrans-62.4-44.2177.7-164.90000111.8S716 P717 R723 S724S716-S720 WeakPolarHBondContact O-CB 3.34Å; S716-S720 PolarHBondContact O-N 3.03Å; P717-S720 PolarHBondContact O-N 2.98Å; S720-R723 PolarHBondContact O-N 3Å; S720-S724 PolarHBondContact O-N 3.11Å
721Y94.9Very high94.9Very high19 Ų1941.8 Ų41.88%0.07522%0.216CC..Hα-helixtrans-66.3-43.7177.4-175.9-136.2000112.3R651 L652 A655 P697 M704 P717 R723 S724 L725R651-Y721 HydrophobicContact CB-CD2 4.1Å; L652-Y721 HydrophobicContact CB-CD2 4.1Å; L652-Y721 HydrophobicContact CB-CE1 4.2Å; L652-Y721 HydrophobicContact CB-CE2 3.71Å; L652-Y721 HydrophobicContact CD1-CE1 4.5Å; L652-Y721 HydrophobicContact CD1-CE2 4.49Å; L652-Y721 WeakPolarHBondContact CD1-OH 3.47Å; L652-Y721 HydrophobicContact CG-CE1 4.23Å; L652-Y721 HydrophobicContact CG-CE2 4.43Å; A655-Y721 HydrophobicContact CB-CD1 4.22Å; A655-Y721 HydrophobicContact CB-CG 4.38Å; P697-Y721 HydrophobicContact CB-CE1 4.18Å; P697-Y721 HydrophobicContact CG-CD1 4.43Å; P697-Y721 HydrophobicContact CG-CE1 3.78Å; M704-Y721 HydrophobicContact SD-CD1 3.69Å; P717-Y721 PolarHBondContact O-N 2.81Å; Y721-R723 VanDerWaalsContact C-N 3.31Å; Y721-R723 PolarHBondContact O-N 3.49Å; Y721-S724 WeakPolarHBondContact O-CA 3.21Å; Y721-S724 WeakPolarHBondContact O-CB 3.2Å; Y721-S724 PolarHBondContact O-N 2.73Å; Y721-L725 HydrophobicContact CD2-CG 4.45Å; Y721-L725 HydrophobicContact CE1-CD1 4.12Å; Y721-L725 HydrophobicContact CE2-CD1 4.44Å; Y721-L725 HydrophobicContact CE2-CD2 3.89Å; Y721-L725 HydrophobicContact CE2-CG 4.05Å; Y721-L725 PolarHBondContact O-N 3.03Å
722L94.7Very high95Very high1 Ų142.1 Ų42.11%0.00522%0.217CC..Hα-helixtrans-59.2-40.5174.1-72.3174.1000112.8I683 L686 V695 M704 F711 Q718 V719 S724 L725 Q726 T739I683-L722 HydrophobicContact CD1-CB 3.73Å; I683-L722 HydrophobicContact CG1-CB 4.47Å; L686-L722 HydrophobicContact CD1-CD1 4.15Å; V695-L722 HydrophobicContact CG1-CD1 4.26Å; V695-L722 HydrophobicContact CG1-CD2 3.81Å; M704-L722 HydrophobicContact CE-CD1 3.93Å; M704-L722 HydrophobicContact CE-CD2 4.04Å; M704-L722 HydrophobicContact CE-CG 3.75Å; F711-L722 HydrophobicContact CE1-CD1 3.87Å; Q718-L722 WeakPolarHBondContact O-CG 3.19Å; Q718-L722 PolarHBondContact O-N 2.77Å; Q718-L722 VanDerWaalsContact O-N 3.11Å; V719-L722 PolarHBondContact O-N 2.77Å; L722-S724 PolarHBondContact O-N 2.87Å; L722-L725 HydrophobicContact CD2-CD1 4.43Å; L722-L725 PolarHBondContact O-N 3.49Å; L722-Q726 PolarHBondContact O-N 2.66Å; L722-T739 HydrophobicContact CD2-CG2 4.12Å
723R95.3Very high95Very high69 Ų6941.7 Ų41.726%0.2621%0.209SC..Hα-helixtrans-63.8-34.5175.2-77.1-180173.4137.3-3.3111.3I683 E684 K714 V719 S720 Y721 S727I683-R723 HydrophobicContact CD1-CB 4.24Å; I683-R723 HydrophobicContact CD1-CG 3.61Å; I683-R723 HydrophobicContact CG1-CG 3.99Å; E684-R723 IonicContact OE1-NE 3.38Å; E684-R723 IonicContact OE2-CZ 3.3Å; E684-R723 IonicContact OE2-NE 3.96Å; E684-R723 IonicContact OE2-NH2 3.61Å; E684-R723 PolarHBondContact OE2-NH2 3.43Å; K714-R723 PolarHBondContact O-NH1 3.17Å; V719-R723 WeakPolarHBondContact O-CG 3.41Å; V719-R723 PolarHBondContact O-N 2.81Å; S720-R723 PolarHBondContact O-N 3Å; Y721-R723 VanDerWaalsContact C-N 3.31Å; Y721-R723 PolarHBondContact O-N 3.49Å; R723-S727 VanDerWaalsContact O-CB 3.24Å; R723-S727 WeakPolarHBondContact O-CB 3.45Å; R723-S727 PolarHBondContact O-N 3.27Å
724S94.7Very high94.9Very high1 Ų138.7 Ų38.71%0.00720%0.201CC..Hα-helixtrans-63.5-45.1174.2-147.10000112.1W642 R651 S720 Y721 L722 S727 W728W642-S724 WeakPolarHBondContact CH2-O 3.31Å; R651-S724 VanDerWaalsContact NH1-CB 3.35Å; R651-S724 PolarHBondContact NH1-OG 3.15Å; S720-S724 PolarHBondContact O-N 3.11Å; Y721-S724 WeakPolarHBondContact O-CA 3.21Å; Y721-S724 WeakPolarHBondContact O-CB 3.2Å; Y721-S724 PolarHBondContact O-N 2.73Å; L722-S724 PolarHBondContact O-N 2.87Å; S724-S727 PolarHBondContact O-N 2.83Å; S724-W728 PolarHBondContact O-N 3.25Å
725L94.5Very high95Very high3 Ų332.6 Ų32.62%0.01618%0.175CC..Hα-helixtrans-63.5-50.3177.2-64.3176.4000111.3P697 Y721 L722 S727 W728 D729 H737 Y749P697-L725 HydrophobicContact CB-CD1 4.15Å; P697-L725 HydrophobicContact CG-CD1 4.01Å; Y721-L725 HydrophobicContact CD2-CG 4.45Å; Y721-L725 HydrophobicContact CE1-CD1 4.12Å; Y721-L725 HydrophobicContact CE2-CD1 4.44Å; Y721-L725 HydrophobicContact CE2-CD2 3.89Å; Y721-L725 HydrophobicContact CE2-CG 4.05Å; Y721-L725 PolarHBondContact O-N 3.03Å; L722-L725 HydrophobicContact CD2-CD1 4.43Å; L722-L725 PolarHBondContact O-N 3.49Å; L725-S727 PolarHBondContact O-N 3.29Å; L725-W728 WeakPolarHBondContact O-CB 3.34Å; L725-W728 PolarHBondContact O-N 3.26Å; L725-W728 VanDerWaalsContact O-N 3.1Å; L725-D729 PolarHBondContact O-N 2.93Å; L725-H737 HydrophobicContact CD2-CB 4.35Å; L725-Y749 HydrophobicContact CB-CE2 4.31Å
726Q95.6Very high95.1Very high26 Ų2631.4 Ų31.412%0.12117%0.165CC..Hα-helixtrans-57.6-39.9175.3-176.2-172.1-81.800111.7L722 H730 Y749L722-Q726 PolarHBondContact O-N 2.66Å; Q726-H730 VanDerWaalsContact CG-CE1 3.5Å; Q726-H730 WeakPolarHBondContact CG-CE1 3.41Å; Q726-H730 PolarHBondContact O-N 3.07Å; Q726-H730 PolarHBondContact O-ND1 3.01Å; Q726-Y749 HydrophobicContact CB-CD1 3.72Å; Q726-Y749 HydrophobicContact CB-CD2 4.38Å; Q726-Y749 HydrophobicContact CB-CE1 3.82Å; Q726-Y749 HydrophobicContact CB-CE2 4.46Å; Q726-Y749 HydrophobicContact CB-CG 4.03Å; Q726-Y749 HydrophobicContact CG-CD1 3.64Å; Q726-Y749 HydrophobicContact CG-CE1 3.99Å; Q726-Y749 HydrophobicContact CG-CG 4.24Å
727S95.7Very high94.9Very high28 Ų2834.6 Ų34.620%0.19618%0.179CC..Hα-helixtrans-63.6-45.9176.7-178.90000110.9R723 S724 L725 D729 H730 H731R723-S727 VanDerWaalsContact O-CB 3.24Å; R723-S727 WeakPolarHBondContact O-CB 3.45Å; R723-S727 PolarHBondContact O-N 3.27Å; S724-S727 PolarHBondContact O-N 2.83Å; L725-S727 PolarHBondContact O-N 3.29Å; S727-D729 PolarHBondContact O-N 3.31Å; S727-H730 PolarHBondContact O-N 3.13Å; S727-H731 PolarHBondContact O-N 2.68Å; S727-H731 VanDerWaalsContact O-N 3.13Å; S727-H731 PolarHBondContact O-ND1 3.43Å; S727-H731 PolarHBondContact OG-CE1 3.36Å; S727-H731 PolarHBondContact OG-ND1 3.02Å
728W95.9Very high94.8Very high11 Ų1138.1 Ų38.14%0.04219%0.192CC..Hα-helixtrans-57.9-50.5177.2176-83.1000111.9A558 M639 W642 L643 S724 L725 H730 H731 F732 F735 H737A558-W728 HydrophobicContact CB-CZ2 3.97Å; M639-W728 HydrophobicContact CB-CH2 4.27Å; M639-W728 HydrophobicContact CG-CH2 4.13Å; M639-W728 HydrophobicContact SD-CH2 4.38Å; W642-W728 HydrophobicContact CD2-CE3 4.01Å; W642-W728 HydrophobicContact CD2-CZ3 4.49Å; W642-W728 AromaticContact CE3-CE3 3.41Å; W642-W728 HydrophobicContact CE3-CE3 3.41Å; W642-W728 VanDerWaalsContact CE3-CE3 3.41Å; W642-W728 AromaticContact CE3-CZ3 3.78Å; W642-W728 HydrophobicContact CE3-CZ3 3.78Å; W642-W728 HydrophobicContact CH2-CB 3.77Å; W642-W728 HydrophobicContact CH2-CE3 4Å; W642-W728 HydrophobicContact CZ2-CB 3.91Å; W642-W728 HydrophobicContact CZ3-CB 4.38Å; W642-W728 HydrophobicContact CZ3-CD2 4.43Å; W642-W728 AromaticContact CZ3-CE3 3.43Å; W642-W728 HydrophobicContact CZ3-CE3 3.43Å; W642-W728 VanDerWaalsContact CZ3-CE3 3.43Å; W642-W728 HydrophobicContact CZ3-CZ3 4.1Å; L643-W728 HydrophobicContact CD2-CE3 4.46Å; L643-W728 HydrophobicContact CD2-CZ3 3.77Å; L643-W728 HydrophobicContact CG-CZ3 4.11Å; S724-W728 PolarHBondContact O-N 3.25Å; L725-W728 WeakPolarHBondContact O-CB 3.34Å; L725-W728 PolarHBondContact O-N 3.26Å; L725-W728 VanDerWaalsContact O-N 3.1Å; W728-H730 PolarHBondContact O-N 3.35Å; W728-H731 PolarHBondContact O-N 3.05Å; W728-F732 AromaticContact CD2-CD2 3.53Å; W728-F732 HydrophobicContact CD2-CD2 3.53Å; W728-F732 HydrophobicContact CD2-CE2 4.09Å; W728-F732 AromaticContact CE2-CD2 3.75Å; W728-F732 AromaticContact CE3-CD2 3.59Å; W728-F732 HydrophobicContact CE3-CD2 3.59Å; W728-F732 AromaticContact CE3-CE2 3.64Å; W728-F732 HydrophobicContact CE3-CE2 3.64Å; W728-F732 HydrophobicContact CG-CD2 4.06Å; W728-F732 HydrophobicContact CH2-CD2 4.13Å; W728-F732 HydrophobicContact CH2-CE2 4.27Å; W728-F732 HydrophobicContact CZ2-CD2 4.06Å; W728-F732 HydrophobicContact CZ2-CG 4.48Å; W728-F732 AromaticContact CZ3-CD2 3.9Å; W728-F732 HydrophobicContact CZ3-CD2 3.9Å; W728-F732 AromaticContact CZ3-CE2 3.74Å; W728-F732 HydrophobicContact CZ3-CE2 3.74Å; W728-F732 PolarHBondContact O-N 3.33Å; W728-F735 HydrophobicContact CZ2-CB 4.48Å; W728-F735 PolarHBondContact NE1-O 3.46Å; W728-H737 AromaticContact CD1-CE1 3.12Å; W728-H737 AromaticContact CD1-ND1 3.34Å; W728-H737 VanDerWaalsContact CD1-ND1 3.34Å; W728-H737 AromaticContact CD2-CE1 3.93Å; W728-H737 AromaticContact CG-CE1 3.34Å; W728-H737 AromaticContact CG-ND1 3.83Å; W728-H737 AromaticContact NE1-CE1 3.55Å
729D95Very high94.7Very high16 Ų1638 Ų389%0.08619%0.192CC..Hα-helixtrans-59.6-34.3-176.3-673.9000112.3L725 S727 E736 H737 Y749L725-D729 PolarHBondContact O-N 2.93Å; S727-D729 PolarHBondContact O-N 3.31Å; D729-E736 HydrophobicContact CB-CB 4.27Å; D729-E736 HydrophobicContact CB-CG 4.09Å; D729-E736 WeakPolarHBondContact OD1-CA 3.44Å; D729-H737 IonicContact OD1-CG 2.9Å; D729-H737 PolarHBondContact OD1-N 2.8Å; D729-H737 IonicContact OD1-ND1 3.87Å; D729-H737 PolarHBondContact OD1-ND1 3.21Å; D729-Y749 PolarHBondContact OD2-OH 3.29Å
730H94.1Very high94.7Very high103 Ų10340.5 Ų40.548%0.47720%0.204SC..Hα-helixtrans-72.2-37.3173.5-72.8125000113.7Q726 S727 W728 G747Q726-H730 VanDerWaalsContact CG-CE1 3.5Å; Q726-H730 WeakPolarHBondContact CG-CE1 3.41Å; Q726-H730 PolarHBondContact O-N 3.07Å; Q726-H730 PolarHBondContact O-ND1 3.01Å; S727-H730 PolarHBondContact O-N 3.13Å; W728-H730 PolarHBondContact O-N 3.35Å; H730-G747 PolarHBondContact CE1-O 3.08Å; H730-G747 WeakPolarHBondContact NE2-CA 3.31Å; H730-G747 PolarHBondContact NE2-O 3.37Å
731H95.5Very high94.7Very high105 Ų10539.9 Ų39.949%0.48620%0.204SC..Hα-helixtrans-78.5-31.1-176.4-74.885.8000112.3W642 S727 W728 P733W642-H731 AromaticContact CD1-CD2 3.98Å; W642-H731 AromaticContact CD1-CG 3.83Å; W642-H731 AromaticContact NE1-CE1 3.84Å; W642-H731 AromaticContact NE1-CG 3.62Å; W642-H731 AromaticContact NE1-ND1 3.45Å; W642-H731 PolarHBondContact NE1-ND1 3.01Å; S727-H731 PolarHBondContact O-N 2.68Å; S727-H731 VanDerWaalsContact O-N 3.13Å; S727-H731 PolarHBondContact O-ND1 3.43Å; S727-H731 PolarHBondContact OG-CE1 3.36Å; S727-H731 PolarHBondContact OG-ND1 3.02Å; W728-H731 PolarHBondContact O-N 3.05Å; H731-P733 WeakPolarHBondContact O-CD 3.19Å
732F96.7Very high94.7Very high7 Ų740.2 Ų40.23%0.03121%0.208CC..SBendtrans-125.172.3-173.5-56.5-67.9000111.7T638 M639 W642 W728 G734 F735T638-F732 HydrophobicContact CG2-CE1 4.03Å; M639-F732 HydrophobicContact CB-CE1 4.26Å; M639-F732 HydrophobicContact CB-CZ 4.25Å; M639-F732 HydrophobicContact CE-CB 4.33Å; M639-F732 HydrophobicContact CE-CD1 4.01Å; M639-F732 HydrophobicContact CE-CG 4.25Å; M639-F732 HydrophobicContact CG-CD1 3.7Å; M639-F732 HydrophobicContact CG-CE1 3.48Å; M639-F732 VanDerWaalsContact CG-CE1 3.48Å; M639-F732 HydrophobicContact CG-CE2 4.37Å; M639-F732 HydrophobicContact CG-CG 4.25Å; M639-F732 HydrophobicContact CG-CZ 3.86Å; W642-F732 HydrophobicContact CB-CE2 3.79Å; W642-F732 HydrophobicContact CB-CZ 3.67Å; W642-F732 AromaticContact CD1-CE2 3.96Å; W642-F732 AromaticContact CD2-CE2 4Å; W642-F732 HydrophobicContact CD2-CE2 4Å; W642-F732 AromaticContact CG-CE2 3.64Å; W642-F732 HydrophobicContact CG-CE2 3.64Å; W642-F732 AromaticContact CG-CZ 3.98Å; W642-F732 HydrophobicContact CG-CZ 3.98Å; W728-F732 AromaticContact CD2-CD2 3.53Å; W728-F732 HydrophobicContact CD2-CD2 3.53Å; W728-F732 HydrophobicContact CD2-CE2 4.09Å; W728-F732 AromaticContact CE2-CD2 3.75Å; W728-F732 AromaticContact CE3-CD2 3.59Å; W728-F732 HydrophobicContact CE3-CD2 3.59Å; W728-F732 AromaticContact CE3-CE2 3.64Å; W728-F732 HydrophobicContact CE3-CE2 3.64Å; W728-F732 HydrophobicContact CG-CD2 4.06Å; W728-F732 HydrophobicContact CH2-CD2 4.13Å; W728-F732 HydrophobicContact CH2-CE2 4.27Å; W728-F732 HydrophobicContact CZ2-CD2 4.06Å; W728-F732 HydrophobicContact CZ2-CG 4.48Å; W728-F732 AromaticContact CZ3-CD2 3.9Å; W728-F732 HydrophobicContact CZ3-CD2 3.9Å; W728-F732 AromaticContact CZ3-CE2 3.74Å; W728-F732 HydrophobicContact CZ3-CE2 3.74Å; W728-F732 PolarHBondContact O-N 3.33Å; F732-G734 PolarHBondContact O-N 3.38Å; F732-F735 HydrophobicContact CB-CB 4.02Å; F732-F735 HydrophobicContact CB-CD2 4.17Å; F732-F735 HydrophobicContact CB-CG 4.46Å; F732-F735 WeakPolarHBondContact O-CB 3.39Å; F732-F735 PolarHBondContact O-N 2.91Å
733P95.6Very high94.8Very high21 Ų2144.7 Ų44.714%0.13623%0.228CC..THydrogen-bonded Turntrans-58134.8175.324.4-33.7000111Y623 T626 Y627 H731 E736Y623-P733 HydrophobicContact CD1-CB 3.6Å; Y623-P733 HydrophobicContact CD1-CG 4.05Å; Y623-P733 HydrophobicContact CD2-CB 4.09Å; Y623-P733 HydrophobicContact CE1-CB 3.48Å; Y623-P733 VanDerWaalsContact CE1-CB 3.48Å; Y623-P733 HydrophobicContact CE1-CG 4.43Å; Y623-P733 HydrophobicContact CE2-CB 4.01Å; Y623-P733 HydrophobicContact CG-CB 3.88Å; Y623-P733 HydrophobicContact CG-CG 4.08Å; T626-P733 HydrophobicContact CG2-CG 4.35Å; Y627-P733 HydrophobicContact CE2-CG 4.17Å; Y627-P733 VanDerWaalsContact CE2-O 3.24Å; Y627-P733 WeakPolarHBondContact CE2-O 3.13Å; Y627-P733 WeakPolarHBondContact OH-CD 3.39Å; Y627-P733 PolarHBondContact OH-O 2.91Å; H731-P733 WeakPolarHBondContact O-CD 3.19Å; P733-E736 WeakPolarHBondContact CA-OE1 3.28Å
734G94.1Very high94.7Very high34 Ų3446.1 Ų46.135%0.35124%0.24SC..THydrogen-bonded Turntrans88.1-0.8-170.700000115.1F732 E736F732-G734 PolarHBondContact O-N 3.38Å; G734-E736 VanDerWaalsContact C-OE2 3.26Å; G734-E736 WeakPolarHBondContact CA-OE2 3.4Å; G734-E736 PolarHBondContact N-OE1 3.12Å; G734-E736 PolarHBondContact N-OE2 3.02Å
735F95.2Very high94.8Very high19 Ų1949.2 Ų49.28%0.08326%0.256CS..  trans-127.126.8175.4-60-92000111.9L559 A562 M616 L619 L635 M639 W728 F732L559-F735 HydrophobicContact CD1-CE1 4.27Å; L559-F735 HydrophobicContact CD1-CZ 4.16Å; A562-F735 HydrophobicContact CB-CD1 4.31Å; A562-F735 HydrophobicContact CB-CE1 3.56Å; A562-F735 HydrophobicContact CB-CZ 4.33Å; M616-F735 HydrophobicContact CE-CZ 4.19Å; L619-F735 HydrophobicContact CD1-CE2 3.96Å; L619-F735 HydrophobicContact CD2-CE2 3.7Å; L619-F735 HydrophobicContact CD2-CZ 3.84Å; L619-F735 HydrophobicContact CG-CE2 4.5Å; L635-F735 HydrophobicContact CD2-CE2 4.11Å; L635-F735 HydrophobicContact CD2-CZ 3.97Å; M639-F735 HydrophobicContact CE-CB 4.32Å; M639-F735 HydrophobicContact CE-CD1 3.65Å; M639-F735 HydrophobicContact CE-CD2 3.43Å; M639-F735 VanDerWaalsContact CE-CD2 3.43Å; M639-F735 HydrophobicContact CE-CE1 3.68Å; M639-F735 HydrophobicContact CE-CE2 3.46Å; M639-F735 VanDerWaalsContact CE-CE2 3.46Å; M639-F735 HydrophobicContact CE-CG 3.52Å; M639-F735 HydrophobicContact CE-CZ 3.59Å; W728-F735 HydrophobicContact CZ2-CB 4.48Å; W728-F735 PolarHBondContact NE1-O 3.46Å; F732-F735 HydrophobicContact CB-CB 4.02Å; F732-F735 HydrophobicContact CB-CD2 4.17Å; F732-F735 HydrophobicContact CB-CG 4.46Å; F732-F735 WeakPolarHBondContact O-CB 3.39Å; F732-F735 PolarHBondContact O-N 2.91Å
736E93.7Very high94.7Very high95 Ų9556.9 Ų56.944%0.44430%0.297SS..PPolyproline II helixtrans-65.3146.5-176.4-5786.2168.500112D729 P733 G734D729-E736 HydrophobicContact CB-CB 4.27Å; D729-E736 HydrophobicContact CB-CG 4.09Å; D729-E736 WeakPolarHBondContact OD1-CA 3.44Å; P733-E736 WeakPolarHBondContact CA-OE1 3.28Å; G734-E736 VanDerWaalsContact C-OE2 3.26Å; G734-E736 WeakPolarHBondContact CA-OE2 3.4Å; G734-E736 PolarHBondContact N-OE1 3.12Å; G734-E736 PolarHBondContact N-OE2 3.02Å
737H91.6Very high94.5Very high73 Ų7356.8 Ų56.834%0.33830%0.303SS..PPolyproline II helixtrans-81.5147.8174.8-63.290.1000111.8L725 W728 D729L725-H737 HydrophobicContact CD2-CB 4.35Å; W728-H737 AromaticContact CD1-CE1 3.12Å; W728-H737 AromaticContact CD1-ND1 3.34Å; W728-H737 VanDerWaalsContact CD1-ND1 3.34Å; W728-H737 AromaticContact CD2-CE1 3.93Å; W728-H737 AromaticContact CG-CE1 3.34Å; W728-H737 AromaticContact CG-ND1 3.83Å; W728-H737 AromaticContact NE1-CE1 3.55Å; D729-H737 IonicContact OD1-CG 2.9Å; D729-H737 PolarHBondContact OD1-N 2.8Å; D729-H737 IonicContact OD1-ND1 3.87Å; D729-H737 PolarHBondContact OD1-ND1 3.21Å
738E92Very high94.5Very high119 Ų11958.8 Ų58.856%0.55631%0.311SS*.EExtended strand (participates in β ladder)trans-89.1117.4164.6-172173.3-172.700109Y698Y698-E738 PolarHBondContact N-O 2.78Å
739T94.1Very high94.5Very high11 Ų1158.5 Ų58.57%0.06731%0.31CS..EExtended strand (participates in β ladder)trans-122.996175.7-53.10000109.9V695 I696 P697 L722 T742V695-T739 HydrophobicContact CG1-CG2 4.08Å; I696-T739 CarbonylContact O-C 3.23Å; I696-T739 WeakPolarHBondContact O-CA 3.08Å; P697-T739 HydrophobicContact CG-CG2 4.32Å; L722-T739 HydrophobicContact CD2-CG2 4.12Å; T739-T742 HydrophobicContact CG2-CG2 3.57Å; T739-T742 PolarHBondContact O-N 3.1Å; T739-T742 PolarHBondContact O-OG1 2.83Å
740E94.8Very high94.6Very high52 Ų5259.2 Ų59.224%0.24331%0.313CS..EExtended strand (participates in β ladder)trans-61.7143.8178.2-51.8-174.4-161.800110.5K257 I696 T742K257-E740 IonicContact NZ-OE1 3.06Å; K257-E740 PolarHBondContact NZ-OE1 3.16Å; K257-E740 IonicContact NZ-OE2 2.69Å; K257-E740 PolarHBondContact NZ-OE2 3.16Å; I696-E740 HydrophobicContact CB-CB 4.09Å; I696-E740 PolarHBondContact N-O 2.88Å; I696-E740 PolarHBondContact O-N 3.43Å; E740-T742 VanDerWaalsContact C-N 3.32Å
741G94.6Very high94.8Very high25 Ų2554.4 Ų54.426%0.25829%0.29SS..THydrogen-bonded Turntrans86.9-0.8-178.700000114.8N693 S694N693-G741 VanDerWaalsContact ND2-CA 3.34Å; N693-G741 WeakPolarHBondContact ND2-CA 3.41Å; N693-G741 PolarHBondContact ND2-O 2.81Å; S694-G741 WeakPolarHBondContact O-CA 2.92Å
742T95.7Very high94.9Very high26 Ų2651.8 Ų51.816%0.1628%0.279CS..EExtended strand (participates in β ladder)trans-108.5151.9172.770.90000111.5V695 T739 E740 Y749 H750 V751V695-T742 HydrophobicContact CG1-CG2 4.05Å; T739-T742 HydrophobicContact CG2-CG2 3.57Å; T739-T742 PolarHBondContact O-N 3.1Å; T739-T742 PolarHBondContact O-OG1 2.83Å; E740-T742 VanDerWaalsContact C-N 3.32Å; T742-Y749 HydrophobicContact CG2-CD2 4.24Å; T742-H750 CarbonylContact C-O 3.54Å; T742-H750 VanDerWaalsContact CA-O 3.28Å; T742-H750 WeakPolarHBondContact CA-O 3.44Å; T742-V751 HydrophobicContact CG2-CG2 4.18Å
743E96Very high95Very high94 Ų9451.4 Ų51.444%0.43928%0.277SS..EExtended strand (participates in β ladder)trans-120.3133.4168-68.6-174.3-168.500109.4L680 Y749 H750L680-E743 VanDerWaalsContact CD1-OE2 3.24Å; L680-E743 WeakPolarHBondContact CD1-OE2 3.3Å; E743-Y749 CarbonylContact O-C 3.59Å; E743-H750 PolarHBondContact N-O 2.95Å; E743-H750 WeakPolarHBondContact O-CB 3.46Å; E743-H750 PolarHBondContact O-N 2.76Å
744I94.3Very high95.1Very high100 Ų10051.5 Ų51.551%0.51328%0.278SS..EExtended strand (participates in β ladder)trans-97.7113177.9-54.8176.8000108.4Y749I744-Y749 HydrophobicContact CD1-CD1 4.28Å; I744-Y749 HydrophobicContact CD1-CE1 3.73Å; I744-Y749 HydrophobicContact CG1-CD1 3.89Å; I744-Y749 HydrophobicContact CG1-CE1 3.87Å
745I95.6Very high95.2Very high65 Ų6554.1 Ų54.133%0.33328%0.279SS..EExtended strand (participates in β ladder)trans-120118178.9-56.2174.5000107.7L680 G747 I748L680-I745 HydrophobicContact CD1-CD1 4.41Å; I745-G747 PolarHBondContact O-N 3.22Å; I745-I748 PolarHBondContact N-O 2.89Å; I745-I748 WeakPolarHBondContact O-CB 3.46Å; I745-I748 PolarHBondContact O-N 3.11Å
746D92.9Very high95Very high164 Ų16460.1 Ų60.188%0.87733%0.332SS*.THydrogen-bonded Turntrans52.138.4-177.4-56.9-38.9000113.1I748D746-I748 PolarHBondContact O-N 2.63Å
747G90.8Very high95Very high24 Ų2458.4 Ų58.425%0.24733%0.326CS..THydrogen-bonded Turntrans81.6-10.6-176.100000114.7H730 I745H730-G747 PolarHBondContact CE1-O 3.08Å; H730-G747 WeakPolarHBondContact NE2-CA 3.31Å; H730-G747 PolarHBondContact NE2-O 3.37Å; I745-G747 PolarHBondContact O-N 3.22Å
748I95.7Very high95.2Very high71 Ų7157.6 Ų57.636%0.36433%0.326SS..EExtended strand (participates in β ladder)trans-94.7129.8-176.4-57.4175.2000110.2I683 I745 D746 H750I683-I748 HydrophobicContact CG2-CG2 4.18Å; I745-I748 PolarHBondContact N-O 2.89Å; I745-I748 WeakPolarHBondContact O-CB 3.46Å; I745-I748 PolarHBondContact O-N 3.11Å; D746-I748 PolarHBondContact O-N 2.63Å; I748-H750 PolarHBondContact O-CE1 3.2Å; I748-H750 PolarHBondContact O-ND1 2.78Å
749Y96.5Very high95.4Very high4 Ų454.2 Ų54.22%0.01631%0.313CS..EExtended strand (participates in β ladder)trans-68.3132173-8136.3000110.2S682 I683 L725 Q726 D729 T742 E743 I744S682-Y749 CarbonylContact C-O 3.48Å; I683-Y749 PolarHBondContact N-O 3.41Å; L725-Y749 HydrophobicContact CB-CE2 4.31Å; Q726-Y749 HydrophobicContact CB-CD1 3.72Å; Q726-Y749 HydrophobicContact CB-CD2 4.38Å; Q726-Y749 HydrophobicContact CB-CE1 3.82Å; Q726-Y749 HydrophobicContact CB-CE2 4.46Å; Q726-Y749 HydrophobicContact CB-CG 4.03Å; Q726-Y749 HydrophobicContact CG-CD1 3.64Å; Q726-Y749 HydrophobicContact CG-CE1 3.99Å; Q726-Y749 HydrophobicContact CG-CG 4.24Å; D729-Y749 PolarHBondContact OD2-OH 3.29Å; T742-Y749 HydrophobicContact CG2-CD2 4.24Å; E743-Y749 CarbonylContact O-C 3.59Å; I744-Y749 HydrophobicContact CD1-CD1 4.28Å; I744-Y749 HydrophobicContact CD1-CE1 3.73Å; I744-Y749 HydrophobicContact CG1-CD1 3.89Å; I744-Y749 HydrophobicContact CG1-CE1 3.87Å
750H97.9Very high95.5Very high31 Ų3156.7 Ų56.714%0.14433%0.328CS..EExtended strand (participates in β ladder)trans-122.4143173.5-67.670.6000109.5L680 V681 S682 T742 E743 I748L680-H750 HydrophobicContact CB-CB 4.44Å; V681-H750 CarbonylContact O-C 3.59Å; V681-H750 VanDerWaalsContact O-CA 3.28Å; V681-H750 WeakPolarHBondContact O-CA 3.38Å; S682-H750 VanDerWaalsContact CA-CD2 3.49Å; S682-H750 WeakPolarHBondContact CA-CD2 3.49Å; S682-H750 PolarHBondContact N-CD2 2.78Å; T742-H750 CarbonylContact C-O 3.54Å; T742-H750 VanDerWaalsContact CA-O 3.28Å; T742-H750 WeakPolarHBondContact CA-O 3.44Å; E743-H750 PolarHBondContact N-O 2.95Å; E743-H750 WeakPolarHBondContact O-CB 3.46Å; E743-H750 PolarHBondContact O-N 2.76Å; I748-H750 PolarHBondContact O-CE1 3.2Å; I748-H750 PolarHBondContact O-ND1 2.78Å
751V97.7Very high95.5Very high2 Ų257 Ų571%0.01233%0.333CS..EExtended strand (participates in β ladder)trans-123.7140.4174.4-172.80000109.6V681 L686 V695 F711 T742 C753V681-V751 PolarHBondContact N-O 2.81Å; V681-V751 PolarHBondContact O-N 3.19Å; L686-V751 HydrophobicContact CD1-CG2 3.94Å; L686-V751 HydrophobicContact CD2-CB 3.82Å; L686-V751 HydrophobicContact CD2-CG2 4.08Å; V695-V751 HydrophobicContact CG2-CG1 3.69Å; V695-V751 HydrophobicContact CG2-CG2 4.32Å; F711-V751 HydrophobicContact CE2-CG1 4.22Å; F711-V751 HydrophobicContact CZ-CB 4.2Å; F711-V751 HydrophobicContact CZ-CG1 3.94Å; F711-V751 HydrophobicContact CZ-CG2 4.13Å; T742-V751 HydrophobicContact CG2-CG2 4.18Å; V751-C753 PolarHBondContact O-N 2.97Å
752M98Very high95.6Very high50 Ų5059.1 Ų59.125%0.24634%0.338CS..EExtended strand (participates in β ladder)trans-71.7115.7173.5-167.9-179.7-64.400109.7I673 V678 L680 A692 N693I673-M752 HydrophobicContact CD1-SD 4.29Å; I673-M752 HydrophobicContact CG1-SD 4.06Å; I673-M752 HydrophobicContact CG2-SD 4.45Å; V678-M752 HydrophobicContact CB-CG 3.84Å; V678-M752 HydrophobicContact CB-SD 4.22Å; V678-M752 HydrophobicContact CG1-CG 4.34Å; V678-M752 HydrophobicContact CG2-CG 4.06Å; V678-M752 HydrophobicContact CG2-SD 3.87Å; L680-M752 HydrophobicContact CD2-CB 4.19Å; A692-M752 HydrophobicContact CB-CB 4.41Å; A692-M752 HydrophobicContact CB-CG 3.96Å; A692-M752 WeakPolarHBondContact CB-O 3.42Å; A692-M752 HydrophobicContact CB-SD 4.44Å; A692-M752 PolarHBondContact N-O 3.37Å; N693-M752 PolarHBondContact OD1-O 2.76Å
753C98.4Very high95.5Very high0 Ų061.5 Ų61.50%035%0.351CS..EExtended strand (participates in β ladder)trans-114.7153.4179.1-61.80000110.6V678 E679 V681 R689 I690 V751 K755V678-C753 CarbonylContact C-O 3.6Å; V678-C753 WeakPolarHBondContact CA-O 3.3Å; V678-C753 WeakPolarHBondContact CB-O 3.41Å; E679-C753 PolarHBondContact N-O 3.37Å; E679-C753 PolarHBondContact O-N 3.01Å; V681-C753 HydrophobicContact CB-CB 4.45Å; V681-C753 HydrophobicContact CG2-CB 3.66Å; R689-C753 HydrophobicContact CB-CB 4.14Å; I690-C753 CarbonylContact O-C 3.17Å; I690-C753 WeakPolarHBondContact O-CA 3.22Å; I690-C753 WeakPolarHBondContact O-CB 3.22Å; V751-C753 PolarHBondContact O-N 2.97Å; C753-K755 PolarHBondContact O-N 3.21Å
754V98Very high95.5Very high23 Ų2359 Ų5914%0.13934%0.344CS..EExtended strand (participates in β ladder)trans-62.8134.4165.5-175.90000107.9A672 R689 I690 A692 A756A672-V754 HydrophobicContact CB-CG1 4.09Å; A672-V754 HydrophobicContact CB-CG2 4.03Å; R689-V754 PolarHBondContact NH2-O 2.94Å; I690-V754 HydrophobicContact CB-CB 4.31Å; I690-V754 HydrophobicContact CB-CG2 4.37Å; I690-V754 HydrophobicContact CG2-CG2 4.08Å; I690-V754 PolarHBondContact O-N 2.84Å; A692-V754 HydrophobicContact CB-CG2 4.27Å; V754-A756 PolarHBondContact O-N 3.32Å
755K96.8Very high95.6Very high89 Ų8955.6 Ų55.639%0.38733%0.33SS..  trans-55.9136.6177.1-75174.7177.8152.90110N676 N677 V678 E679 C753N676-K755 PolarHBondContact O-NZ 2.96Å; N677-K755 PolarHBondContact O-N 3.27Å; V678-K755 WeakPolarHBondContact O-CE 2.85Å; E679-K755 HydrophobicContact CB-CG 4.31Å; E679-K755 HydrophobicContact CG-CG 4.17Å; C753-K755 PolarHBondContact O-N 3.21Å
756A89Confident95.6Very high144 Ų14454.7 Ų54.7100%1.1933%0.329SS*.  trans-690-175.600000113.6V754V754-A756 PolarHBondContact O-N 3.32Å

Retrieved 756 of 756 residues in 372.1 ms (Link to these results)