A0A077ZEA8_TRITR Loading...

Protein angel 2

AlphaFold DB , UniProt , Accession A0A077ZEA8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 375 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M44.9Very low77.3Confident231 Ų23186.6 Ų86.6100%1.13846%0.461SS*.  0111.90-147.8169.8178.500106.1M3M1-M3 PolarHBondContact O-N 2.94Å
2M49Very low79.1Confident192 Ų19279.4 Ų79.495%0.94642%0.422SS*.PPolyproline II helixtrans-63.9117174.1-76.7-175.7175.700107L4M2-L4 PolarHBondContact O-N 2.9Å
3M54Low80.6Confident148 Ų14873.4 Ų73.473%0.72939%0.391SS*.PPolyproline II helixtrans-67125.6169.2-66.1-154.9-62.300107M1 N5M1-M3 PolarHBondContact O-N 2.94Å; M3-N5 PolarHBondContact O-N 3.19Å
4L63.5Low81.9Confident70 Ų7068.1 Ų68.137%0.36636%0.363SS..PPolyproline II helixtrans-57139.2170.8-72.5167.3000108.3M2 H375M2-L4 PolarHBondContact O-N 2.9Å; L4-H375 HydrophobicContact CB-CB 4.32Å; L4-H375 WeakPolarHBondContact CB-CD2 3.39Å; L4-H375 HydrophobicContact CD1-CB 4.13Å
5N75Confident83Confident144 Ų14463.6 Ų63.677%0.7734%0.338SS*.PPolyproline II helixtrans-58.6134.5175.3-73.8-18.1000109M3M3-N5 PolarHBondContact O-N 3.19Å
6P84Confident84Confident60 Ų6059.6 Ų59.639%0.3932%0.317SS..PPolyproline II helixtrans-54.7144.4175.1-24.333.3000111.6E372 F373 V374P6-E372 HydrophobicContact CB-CB 4.11Å; P6-E372 HydrophobicContact CB-CG 4.09Å; P6-F373 CarbonylContact C-O 3.48Å; P6-F373 VanDerWaalsContact CA-O 3.27Å; P6-F373 WeakPolarHBondContact CA-O 3.4Å; P6-V374 HydrophobicContact CB-CG2 4.37Å; P6-V374 HydrophobicContact CG-CG2 4.34Å
7I90.1Very high84.8Confident32 Ų3256.5 Ų56.516%0.16430%0.3CS..EExtended strand (participates in β ladder)trans-90114.4175.5-61.1174000107.9V135 F373 H375I7-V135 HydrophobicContact CB-CG1 4.22Å; I7-V135 HydrophobicContact CD1-CG1 3.71Å; I7-V135 HydrophobicContact CG2-CG1 3.86Å; I7-F373 HydrophobicContact CB-CB 4.47Å; I7-F373 PolarHBondContact N-O 3.17Å; I7-F373 PolarHBondContact O-N 3.49Å; I7-H375 VanDerWaalsContact CD1-CE1 3.47Å; I7-H375 WeakPolarHBondContact CD1-CE1 3.42Å
8A94.5Very high85.5Confident48 Ų4853.4 Ų53.440%0.39728%0.284SS..EExtended strand (participates in β ladder)trans-82.8136.8173.800000111.1F371A8-F371 CarbonylContact C-O 3.53Å; A8-F371 VanDerWaalsContact CA-O 3.29Å; A8-F371 WeakPolarHBondContact CA-O 3.44Å
9F97.5Very high86.1Confident1 Ų150.8 Ų50.80%0.00427%0.27CS..EExtended strand (participates in β ladder)trans-149.3159.6171.871.7-83.1000111.1D56 I57 F105 I151 I194 L334 E370 F371 F373F9-D56 WeakPolarHBondContact CA-OD2 3.24Å; F9-D56 HydrophobicContact CB-CB 4.15Å; F9-I57 HydrophobicContact CD2-CD1 4.2Å; F9-I57 HydrophobicContact CE2-CD1 4.1Å; F9-F105 HydrophobicContact CB-CE2 4.37Å; F9-F105 HydrophobicContact CB-CZ 3.84Å; F9-F105 HydrophobicContact CD1-CZ 4.31Å; F9-F105 AromaticContact CD2-CZ 3.75Å; F9-F105 HydrophobicContact CD2-CZ 3.75Å; F9-F105 HydrophobicContact CE2-CZ 4.4Å; F9-F105 AromaticContact CG-CZ 3.7Å; F9-F105 HydrophobicContact CG-CZ 3.7Å; F9-I151 HydrophobicContact CE1-CD1 4.25Å; F9-I151 HydrophobicContact CE2-CD1 4.31Å; F9-I151 HydrophobicContact CZ-CD1 3.5Å; F9-I194 HydrophobicContact CE2-CD1 4Å; F9-I194 HydrophobicContact CZ-CD1 3.91Å; F9-L334 HydrophobicContact CE1-CD1 3.89Å; F9-L334 HydrophobicContact CZ-CD1 3.89Å; F9-E370 CarbonylContact O-C 3.46Å; F9-E370 WeakPolarHBondContact O-CA 3.31Å; F9-F371 HydrophobicContact CD1-CB 4.21Å; F9-F371 HydrophobicContact CE1-CB 3.65Å; F9-F371 HydrophobicContact CE2-CB 4.14Å; F9-F371 HydrophobicContact CE2-CD2 4.14Å; F9-F371 HydrophobicContact CE2-CG 4.42Å; F9-F371 HydrophobicContact CZ-CB 3.6Å; F9-F371 HydrophobicContact CZ-CD2 4.28Å; F9-F371 HydrophobicContact CZ-CG 4.1Å; F9-F371 PolarHBondContact N-O 3.46Å; F9-F371 PolarHBondContact O-N 3.02Å; F9-F373 HydrophobicContact CE1-CB 4.23Å
10T98.7Very high86.6Confident27 Ų2750.8 Ų50.817%0.16627%0.27CS..EExtended strand (participates in β ladder)trans-109.7147.7177.2490000111.7A55 D56 I57 A369 E370T10-A55 WeakPolarHBondContact OG1-CA 3.16Å; T10-D56 PolarHBondContact N-OD2 3.16Å; T10-D56 WeakPolarHBondContact O-CB 3.47Å; T10-D56 PolarHBondContact O-N 3.39Å; T10-D56 VanDerWaalsContact O-N 3.13Å; T10-D56 PolarHBondContact OG1-N 2.74Å; T10-D56 PolarHBondContact OG1-OD2 3.33Å; T10-I57 PolarHBondContact O-N 3.48Å; T10-A369 CarbonylContact C-O 3.59Å; T10-A369 VanDerWaalsContact CA-O 3.23Å; T10-A369 WeakPolarHBondContact CA-O 3.5Å; T10-E370 HydrophobicContact CG2-CB 4.02Å; T10-E370 HydrophobicContact CG2-CG 4.18Å
11L98.8Very high86.9Confident0 Ų050.8 Ų50.80%027%0.272CS..EExtended strand (participates in β ladder)trans-130.6131.5171.6-174.4150.7000109.8I57 V153 I194 M311 L368 A369 F371L11-I57 CarbonylContact C-O 3.53Å; L11-I57 VanDerWaalsContact CA-O 3.29Å; L11-I57 WeakPolarHBondContact CA-O 3.24Å; L11-I57 HydrophobicContact CB-CB 4.3Å; L11-I57 HydrophobicContact CD1-CB 4.06Å; L11-I57 HydrophobicContact CD1-CD1 4.4Å; L11-I57 HydrophobicContact CD1-CG2 3.79Å; L11-I57 HydrophobicContact CG-CB 4.04Å; L11-I57 HydrophobicContact CG-CG2 4.03Å; L11-V153 HydrophobicContact CD1-CG1 3.73Å; L11-V153 HydrophobicContact CD1-CG2 4.13Å; L11-I194 HydrophobicContact CD1-CB 4.31Å; L11-I194 HydrophobicContact CD1-CD1 3.99Å; L11-I194 HydrophobicContact CD1-CG2 3.92Å; L11-I194 HydrophobicContact CD2-CG2 4.35Å; L11-M311 HydrophobicContact CD2-CE 3.41Å; L11-M311 VanDerWaalsContact CD2-CE 3.41Å; L11-M311 HydrophobicContact CD2-SD 3.94Å; L11-L368 WeakPolarHBondContact O-CA 3.49Å; L11-A369 PolarHBondContact N-O 3.32Å; L11-A369 PolarHBondContact O-N 3.21Å; L11-F371 HydrophobicContact CB-CD2 4.38Å; L11-F371 HydrophobicContact CB-CE2 4.05Å
12C98.9Very high89.3Confident0 Ų039.9 Ų39.90%022%0.219CC..EExtended strand (participates in β ladder)trans-112.5127.3175.4-176.60000110.2A55 I57 F58 C59 L367 L368C12-A55 HydrophobicContact CB-CB 3.55Å; C12-I57 PolarHBondContact N-O 3.02Å; C12-F58 HydrophobicContact CB-CD1 3.58Å; C12-F58 HydrophobicContact CB-CE1 3.72Å; C12-F58 HydrophobicContact CB-CG 4.32Å; C12-F58 CarbonylContact O-C 3.57Å; C12-F58 WeakPolarHBondContact O-CA 3.41Å; C12-C59 PolarHBondContact O-N 2.65Å; C12-L367 CarbonylContact C-O 3.49Å; C12-L367 VanDerWaalsContact CA-O 3.27Å; C12-L367 WeakPolarHBondContact CA-O 3.43Å; C12-L368 HydrophobicContact CB-CD1 3.87Å
13S98.8Very high91.5Very high1 Ų135.8 Ų35.81%0.00720%0.197CC..EExtended strand (participates in β ladder)trans-105.4128.5166.7-173.50000109.2C59 Q61 G197 L367S13-C59 CarbonylContact C-O 3.49Å; S13-C59 WeakPolarHBondContact CA-O 3.31Å; S13-Q61 PolarHBondContact OG-NE2 3.34Å; S13-G197 WeakPolarHBondContact OG-CA 3.19Å; S13-G197 PolarHBondContact OG-N 3.48Å; S13-L367 PolarHBondContact N-O 2.86Å; S13-L367 PolarHBondContact O-N 2.98Å
14Y98.7Very high93.3Very high0 Ų038.1 Ų38.10%020%0.198CC..EExtended strand (participates in β ladder)trans-151.2116.7-174.9-170-170.9000112.3V16 L46 E49 F50 C59 L60 Q61 S362 H364 P366Y14-V16 HydrophobicContact CD1-CG1 4.17Å; Y14-V16 HydrophobicContact CG-CG1 4.24Å; Y14-V16 PolarHBondContact O-N 2.81Å; Y14-L46 HydrophobicContact CE1-CD2 3.89Å; Y14-E49 WeakPolarHBondContact CE1-OE2 3.37Å; Y14-E49 PolarHBondContact OH-OE1 2.84Å; Y14-E49 PolarHBondContact OH-OE2 2.89Å; Y14-F50 AromaticContact CD1-CE1 3.84Å; Y14-F50 HydrophobicContact CD1-CE1 3.84Å; Y14-F50 HydrophobicContact CE1-CE1 4.19Å; Y14-C59 PolarHBondContact N-O 2.81Å; Y14-L60 VanDerWaalsContact O-CA 3.26Å; Y14-L60 WeakPolarHBondContact O-CA 3.27Å; Y14-Q61 PolarHBondContact O-N 2.84Å; Y14-Q61 PolarHBondContact O-OE1 2.92Å; Y14-S362 VanDerWaalsContact CE2-CB 3.49Å; Y14-S362 VanDerWaalsContact OH-CB 3.27Å; Y14-S362 WeakPolarHBondContact OH-CB 3.43Å; Y14-H364 HydrophobicContact CE2-CB 4.39Å; Y14-H364 VanDerWaalsContact CE2-O 3.31Å; Y14-H364 WeakPolarHBondContact CE2-O 3.4Å; Y14-P366 HydrophobicContact CD1-CB 4.05Å; Y14-P366 HydrophobicContact CD2-CB 4.27Å; Y14-P366 HydrophobicContact CE1-CB 4.47Å; Y14-P366 HydrophobicContact CG-CB 3.95Å
15N98.6Very high94.6Very high0 Ų036.3 Ų36.30%019%0.19CC..EExtended strand (participates in β ladder)trans-74.3115.8166.3-176-17.8000108.7L17 Q61 E62 D198 S362 H364N15-L17 PolarHBondContact OD1-N 3.07Å; N15-Q61 HydrophobicContact CB-CB 4.1Å; N15-E62 PolarHBondContact ND2-OE1 2.95Å; N15-E62 VanDerWaalsContact ND2-OE1 3.1Å; N15-E62 VanDerWaalsContact OD1-CB 3.31Å; N15-E62 WeakPolarHBondContact OD1-CB 3.49Å; N15-E62 WeakPolarHBondContact OD1-CG 3.19Å; N15-D198 PolarHBondContact ND2-OD2 3.2Å; N15-S362 WeakPolarHBondContact O-CB 3.19Å; N15-S362 PolarHBondContact O-OG 2.88Å; N15-H364 HydrophobicContact CB-CB 3.97Å; N15-H364 PolarHBondContact ND2-NE2 2.76Å
16V98.4Very high95.4Very high0 Ų033.2 Ų33.20%017%0.172CC..  trans-93.85.6-172.9-59.80000113.5Y14 R42 L46 F50 L60 Q61 V63 Y72Y14-V16 HydrophobicContact CD1-CG1 4.17Å; Y14-V16 HydrophobicContact CG-CG1 4.24Å; Y14-V16 PolarHBondContact O-N 2.81Å; V16-R42 PolarHBondContact O-NH2 2.85Å; V16-L46 HydrophobicContact CB-CD1 4.25Å; V16-L46 HydrophobicContact CB-CD2 4.3Å; V16-L46 HydrophobicContact CG1-CD2 4.33Å; V16-F50 HydrophobicContact CG1-CE1 4.21Å; V16-F50 HydrophobicContact CG1-CZ 3.84Å; V16-L60 HydrophobicContact CG1-CB 4.32Å; V16-L60 HydrophobicContact CG1-CD1 4.37Å; V16-L60 HydrophobicContact CG1-CD2 4.05Å; V16-L60 HydrophobicContact CG1-CG 4.48Å; V16-Q61 VanDerWaalsContact CG2-O 3.23Å; V16-Q61 WeakPolarHBondContact CG2-O 3.29Å; V16-Q61 PolarHBondContact N-O 2.85Å; V16-V63 HydrophobicContact CG2-CG2 3.83Å; V16-Y72 HydrophobicContact CG2-CE1 4.12Å; V16-Y72 WeakPolarHBondContact CG2-OH 3.37Å
17L97.6Very high95.8Very high6 Ų638.2 Ų38.23%0.03118%0.184CC..  trans53.9105.1178.1173.569.4000113.6N15 Q19 M22 Y29 R42 P356 D363N15-L17 PolarHBondContact OD1-N 3.07Å; L17-Q19 PolarHBondContact O-N 3Å; L17-M22 HydrophobicContact CD1-CB 4.09Å; L17-M22 HydrophobicContact CD2-CB 4.11Å; L17-M22 HydrophobicContact CD2-CG 3.87Å; L17-M22 HydrophobicContact CD2-SD 3.76Å; L17-M22 HydrophobicContact CG-CB 4.06Å; L17-M22 HydrophobicContact CG-CG 4.38Å; L17-Y29 VanDerWaalsContact CD1-OH 3.29Å; L17-Y29 WeakPolarHBondContact CD1-OH 3.42Å; L17-Y29 HydrophobicContact CD2-CE1 4.05Å; L17-R42 VanDerWaalsContact CB-NH2 3.32Å; L17-R42 VanDerWaalsContact O-CZ 3.31Å; L17-R42 PolarHBondContact O-NH1 2.93Å; L17-R42 PolarHBondContact O-NH2 3.2Å; L17-P356 HydrophobicContact CD2-CG 4.32Å; L17-D363 WeakPolarHBondContact CB-OD1 3.19Å; L17-D363 HydrophobicContact CD2-CB 4.41Å
18C97.6Very high95.9Very high1 Ų139 Ų391%0.00719%0.188CC..  trans-62.7131.4-178.5169.30000111.1D20 T21 M22 E62 Q64 D94C18-D20 PolarHBondContact O-N 3.17Å; C18-T21 PolarHBondContact O-N 3.23Å; C18-M22 WeakPolarHBondContact O-CB 3.14Å; C18-M22 PolarHBondContact O-N 3.16Å; C18-E62 WeakPolarHBondContact CA-O 3.34Å; C18-E62 HydrophobicContact CB-CB 4.02Å; C18-E62 WeakPolarHBondContact CB-O 3.41Å; C18-E62 PolarHBondContact N-O 3.15Å; C18-E62 PolarHBondContact N-OE2 3.31Å; C18-Q64 PolarHBondContact SG-OE1 2.8Å; C18-D94 HydrophobicContact CB-CB 3.7Å
19Q97.5Very high95.8Very high5 Ų537.2 Ų37.22%0.02317%0.171CC..Hα-helixtrans-58.9-48.3-178.8-175.26921.600111.8L17 T21 M22 E23 I37 W39 Q64L17-Q19 PolarHBondContact O-N 3Å; Q19-T21 VanDerWaalsContact C-N 3.28Å; Q19-T21 PolarHBondContact O-N 3.03Å; Q19-M22 VanDerWaalsContact NE2-CE 3.26Å; Q19-M22 PolarHBondContact O-N 2.73Å; Q19-E23 HydrophobicContact CG-CG 4.41Å; Q19-E23 WeakPolarHBondContact CG-OE1 3.31Å; Q19-E23 PolarHBondContact NE2-OE1 2.88Å; Q19-E23 WeakPolarHBondContact O-CG 3.21Å; Q19-E23 PolarHBondContact O-N 3.03Å; Q19-I37 PolarHBondContact NE2-O 2.93Å; Q19-W39 HydrophobicContact CB-CE3 4.29Å; Q19-W39 HydrophobicContact CG-CB 4.05Å; Q19-Q64 VanDerWaalsContact CB-OE1 3.32Å; Q19-Q64 VanDerWaalsContact N-OE1 3.14Å
20D96.5Very high95.6Very high49 Ų4943.7 Ų43.726%0.26220%0.201SC..Hα-helixtrans-59.1-38.1177.6-79.124.8000112.4C18 R24 Q64 A93C18-D20 PolarHBondContact O-N 3.17Å; D20-R24 WeakPolarHBondContact O-CD 3.15Å; D20-R24 WeakPolarHBondContact O-CG 3.47Å; D20-R24 PolarHBondContact O-N 3.46Å; D20-Q64 PolarHBondContact OD1-NE2 2.87Å; D20-Q64 PolarHBondContact OD1-OE1 3.43Å; D20-A93 HydrophobicContact CB-CB 3.84Å
21T93.2Very high95.3Very high51 Ų5145.5 Ų45.531%0.31321%0.21SC..Hα-helixtrans-68.8-45.4177.7-61.90000110.6C18 Q19 R24 T25C18-T21 PolarHBondContact O-N 3.23Å; Q19-T21 VanDerWaalsContact C-N 3.28Å; Q19-T21 PolarHBondContact O-N 3.03Å; T21-R24 PolarHBondContact O-N 3.4Å; T21-T25 PolarHBondContact O-N 3.3Å; T21-T25 VanDerWaalsContact O-N 3.11Å; T21-T25 PolarHBondContact O-OG1 2.72Å
22M94.3Very high95Very high3 Ų346.4 Ų46.42%0.01522%0.215CC..Hα-helixtrans-61.2-45.3177.4-174.4-166.973.200111.5L17 C18 Q19 R24 T25 M26 Y29 I37 P356L17-M22 HydrophobicContact CD1-CB 4.09Å; L17-M22 HydrophobicContact CD2-CB 4.11Å; L17-M22 HydrophobicContact CD2-CG 3.87Å; L17-M22 HydrophobicContact CD2-SD 3.76Å; L17-M22 HydrophobicContact CG-CB 4.06Å; L17-M22 HydrophobicContact CG-CG 4.38Å; C18-M22 WeakPolarHBondContact O-CB 3.14Å; C18-M22 PolarHBondContact O-N 3.16Å; Q19-M22 VanDerWaalsContact NE2-CE 3.26Å; Q19-M22 PolarHBondContact O-N 2.73Å; M22-R24 VanDerWaalsContact C-N 3.32Å; M22-R24 PolarHBondContact O-N 3.43Å; M22-T25 CarbonylContact O-C 3.15Å; M22-T25 WeakPolarHBondContact O-CA 3.25Å; M22-T25 PolarHBondContact O-N 3.15Å; M22-T25 PolarHBondContact O-OG1 3.4Å; M22-M26 WeakPolarHBondContact O-CA 3.4Å; M22-M26 PolarHBondContact O-N 3.47Å; M22-Y29 HydrophobicContact CB-CE2 4.24Å; M22-Y29 HydrophobicContact CG-CD2 3.74Å; M22-Y29 HydrophobicContact CG-CE1 4.35Å; M22-Y29 HydrophobicContact CG-CE2 3.39Å; M22-Y29 HydrophobicContact CG-CG 4.37Å; M22-I37 HydrophobicContact CE-CB 3.91Å; M22-I37 HydrophobicContact CE-CG1 4.34Å; M22-I37 WeakPolarHBondContact CE-O 3.16Å; M22-I37 HydrophobicContact SD-CB 4.11Å; M22-P356 HydrophobicContact SD-CG 4.15Å
23E94.4Very high94.7Very high105 Ų10554.4 Ų54.449%0.49125%0.246SC..Hα-helixtrans-63.2-36.7178.3-74176.7-174.600112.3Q19 T25Q19-E23 HydrophobicContact CG-CG 4.41Å; Q19-E23 WeakPolarHBondContact CG-OE1 3.31Å; Q19-E23 PolarHBondContact NE2-OE1 2.88Å; Q19-E23 WeakPolarHBondContact O-CG 3.21Å; Q19-E23 PolarHBondContact O-N 3.03Å; E23-T25 PolarHBondContact O-N 2.83Å
24R92.9Very high94.2Very high197 Ų19760.7 Ų60.774%0.74328%0.275SS*.Hα-helixtrans-69.2-22172.9-69.9169.9-165-87.5-0.9113.2D20 T21 M22D20-R24 WeakPolarHBondContact O-CD 3.15Å; D20-R24 WeakPolarHBondContact O-CG 3.47Å; D20-R24 PolarHBondContact O-N 3.46Å; T21-R24 PolarHBondContact O-N 3.4Å; M22-R24 VanDerWaalsContact C-N 3.32Å; M22-R24 PolarHBondContact O-N 3.43Å
25T91.5Very high93.9Very high33 Ų3364.4 Ų64.420%0.20230%0.301CS..THydrogen-bonded Turntrans-114.724.5-178.256.10000112.2T21 M22 E23 Y27 L28T21-T25 PolarHBondContact O-N 3.3Å; T21-T25 VanDerWaalsContact O-N 3.11Å; T21-T25 PolarHBondContact O-OG1 2.72Å; M22-T25 CarbonylContact O-C 3.15Å; M22-T25 WeakPolarHBondContact O-CA 3.25Å; M22-T25 PolarHBondContact O-N 3.15Å; M22-T25 PolarHBondContact O-OG1 3.4Å; E23-T25 PolarHBondContact O-N 2.83Å; T25-Y27 HydrophobicContact CG2-CE1 4.47Å; T25-Y27 PolarHBondContact O-N 3.35Å; T25-L28 VanDerWaalsContact O-CB 3.31Å; T25-L28 WeakPolarHBondContact O-CB 3.5Å; T25-L28 WeakPolarHBondContact O-CG 3.29Å; T25-L28 PolarHBondContact O-N 2.74Å
26M90.9Very high93.5Very high79 Ų7965.8 Ų65.839%0.38931%0.307SS..G310 helixtrans-54.1-28.5-172.9-162.8-175-163.500113.9M22 L28 Y29 E34 I37M22-M26 WeakPolarHBondContact O-CA 3.4Å; M22-M26 PolarHBondContact O-N 3.47Å; M26-L28 PolarHBondContact O-N 3.11Å; M26-L28 VanDerWaalsContact O-N 3.17Å; M26-Y29 PolarHBondContact O-N 3.22Å; M26-E34 HydrophobicContact CE-CG 3.97Å; M26-I37 HydrophobicContact CE-CD1 3.85Å; M26-I37 HydrophobicContact CG-CD1 4.32Å
27Y91.7Very high93.3Very high165 Ų16566 Ų6665%0.64731%0.309SS*.G310 helixtrans-59.2-23.9175.767.8-89.7000113.7T25 Y29 H30T25-Y27 HydrophobicContact CG2-CE1 4.47Å; T25-Y27 PolarHBondContact O-N 3.35Å; Y27-Y29 VanDerWaalsContact C-N 3.3Å; Y27-H30 PolarHBondContact O-ND1 3.19Å
28L92.5Very high93.2Very high49 Ų4969.6 Ų69.626%0.25733%0.325SS..G310 helixtrans-71.4-25.3174.3-64.2179.8000112.6T25 M26 I301T25-L28 VanDerWaalsContact O-CB 3.31Å; T25-L28 WeakPolarHBondContact O-CB 3.5Å; T25-L28 WeakPolarHBondContact O-CG 3.29Å; T25-L28 PolarHBondContact O-N 2.74Å; M26-L28 PolarHBondContact O-N 3.11Å; M26-L28 VanDerWaalsContact O-N 3.17Å; L28-I301 HydrophobicContact CB-CG2 3.7Å; L28-I301 HydrophobicContact CD1-CG2 4.38Å; L28-I301 HydrophobicContact CG-CG2 4.46Å
29Y93.6Very high93.2Very high9 Ų971.1 Ų71.14%0.03533%0.331CS..G310 helixtrans-104.623-173-52-82.7000113L17 M22 M26 Y27 L31 C32 I301 D363L17-Y29 VanDerWaalsContact CD1-OH 3.29Å; L17-Y29 WeakPolarHBondContact CD1-OH 3.42Å; L17-Y29 HydrophobicContact CD2-CE1 4.05Å; M22-Y29 HydrophobicContact CB-CE2 4.24Å; M22-Y29 HydrophobicContact CG-CD2 3.74Å; M22-Y29 HydrophobicContact CG-CE1 4.35Å; M22-Y29 HydrophobicContact CG-CE2 3.39Å; M22-Y29 HydrophobicContact CG-CG 4.37Å; M26-Y29 PolarHBondContact O-N 3.22Å; Y27-Y29 VanDerWaalsContact C-N 3.3Å; Y29-L31 PolarHBondContact O-N 2.58Å; Y29-L31 VanDerWaalsContact O-N 3.13Å; Y29-C32 VanDerWaalsContact O-CB 3.31Å; Y29-C32 WeakPolarHBondContact O-CB 3.5Å; Y29-C32 PolarHBondContact O-N 2.86Å; Y29-I301 HydrophobicContact CE1-CG2 4.38Å; Y29-D363 HydrophobicContact CE1-CB 4.19Å; Y29-D363 PolarHBondContact OH-OD2 2.91Å
30H91.5Very high93.1Very high137 Ų13774.4 Ų74.463%0.63436%0.359SS*.THydrogen-bonded Turntrans-63.8-16.5-178.564.6-85.8000114.4Y27Y27-H30 PolarHBondContact O-ND1 3.19Å
31L92.7Very high93.1Very high66 Ų6678 Ų7835%0.34637%0.372SS..THydrogen-bonded Turntrans-89.2-9.3173.6-60.4177.9000113Y29 I303 Y354Y29-L31 PolarHBondContact O-N 2.58Å; Y29-L31 VanDerWaalsContact O-N 3.13Å; L31-I303 HydrophobicContact CD1-CG2 4.35Å; L31-Y354 HydrophobicContact CB-CD1 4.06Å; L31-Y354 HydrophobicContact CB-CD2 3.82Å; L31-Y354 HydrophobicContact CB-CE1 4.3Å; L31-Y354 HydrophobicContact CB-CE2 4.08Å; L31-Y354 HydrophobicContact CB-CG 3.82Å; L31-Y354 HydrophobicContact CD1-CD1 3.99Å; L31-Y354 HydrophobicContact CD1-CE1 3.53Å; L31-Y354 HydrophobicContact CD1-CE2 4.29Å
32C93.7Very high93.3Very high18 Ų1875.6 Ų75.612%0.12236%0.357CS..SBendtrans-86.8156.3176.6-560000110.4Y29 E34 I37 L355Y29-C32 VanDerWaalsContact O-CB 3.31Å; Y29-C32 WeakPolarHBondContact O-CB 3.5Å; Y29-C32 PolarHBondContact O-N 2.86Å; C32-E34 PolarHBondContact O-N 2.82Å; C32-I37 HydrophobicContact CB-CG2 3.58Å; C32-L355 VanDerWaalsContact SG-C 3.52Å; C32-L355 PolarHBondContact SG-O 3.25Å
33R91.5Very high93.5Very high168 Ų16877.2 Ų77.263%0.63436%0.363SS*.  trans-76.1125.1171.7-70.2168.5176.7173.62.8109.2S35 E36 I37R33-S35 PolarHBondContact O-N 3.27Å; R33-S35 VanDerWaalsContact O-N 3.08Å; R33-E36 HydrophobicContact CB-CB 4.22Å; R33-E36 HydrophobicContact CB-CG 3.94Å; R33-E36 VanDerWaalsContact CD-CD 3.47Å; R33-E36 WeakPolarHBondContact CD-OE1 3.43Å; R33-E36 IonicContact CZ-OE1 2.73Å; R33-E36 IonicContact NE-OE1 3.22Å; R33-E36 IonicContact NH1-OE1 3.63Å; R33-E36 PolarHBondContact NH1-OE1 2.83Å; R33-E36 PolarHBondContact O-N 3.3Å; R33-I37 PolarHBondContact O-N 3.47Å
34E89.2Confident93.7Very high133 Ų13377.4 Ų77.462%0.62136%0.364SS*.THydrogen-bonded Turntrans-54.9-32.8-177.5-173.9177.3-175.600113.5M26 C32 I37 Q38M26-E34 HydrophobicContact CE-CG 3.97Å; C32-E34 PolarHBondContact O-N 2.82Å; E34-I37 VanDerWaalsContact O-CG1 3.31Å; E34-I37 WeakPolarHBondContact O-CG1 3.33Å; E34-Q38 WeakPolarHBondContact O-CG 3.23Å; E34-Q38 PolarHBondContact O-NE2 3.25Å; E34-Q38 VanDerWaalsContact O-NE2 3.14Å
35S92.1Very high93.9Very high78 Ų7868.2 Ų68.255%0.54533%0.33SS..THydrogen-bonded Turntrans-70.7-29.6176.657.70000113.4R33 K41R33-S35 PolarHBondContact O-N 3.27Å; R33-S35 VanDerWaalsContact O-N 3.08Å; S35-K41 VanDerWaalsContact O-CG 3.24Å; S35-K41 WeakPolarHBondContact O-CG 3.45Å
36E91.1Very high94.2Very high29 Ų2966.6 Ų66.614%0.13632%0.32CS..THydrogen-bonded Turntrans-81.4-27.3-177.4-66177.3179.500111.6R33 Q38 R42 N357 A358R33-E36 HydrophobicContact CB-CB 4.22Å; R33-E36 HydrophobicContact CB-CG 3.94Å; R33-E36 VanDerWaalsContact CD-CD 3.47Å; R33-E36 WeakPolarHBondContact CD-OE1 3.43Å; R33-E36 IonicContact CZ-OE1 2.73Å; R33-E36 IonicContact NE-OE1 3.22Å; R33-E36 IonicContact NH1-OE1 3.63Å; R33-E36 PolarHBondContact NH1-OE1 2.83Å; R33-E36 PolarHBondContact O-N 3.3Å; E36-Q38 VanDerWaalsContact C-N 3.3Å; E36-Q38 PolarHBondContact O-N 2.82Å; E36-R42 WeakPolarHBondContact O-CG 3.26Å; E36-N357 WeakPolarHBondContact OE2-CA 3.48Å; E36-N357 WeakPolarHBondContact OE2-CB 3.32Å; E36-A358 HydrophobicContact CG-CB 4.4Å; E36-A358 PolarHBondContact OE2-N 2.79Å
37I93.2Very high94.6Very high5 Ų563.5 Ų63.53%0.02631%0.306CS..SBendtrans-82.9-3.5176.173.4175.3000113.2Q19 M22 M26 C32 R33 E34 R42 P356Q19-I37 PolarHBondContact NE2-O 2.93Å; M22-I37 HydrophobicContact CE-CB 3.91Å; M22-I37 HydrophobicContact CE-CG1 4.34Å; M22-I37 WeakPolarHBondContact CE-O 3.16Å; M22-I37 HydrophobicContact SD-CB 4.11Å; M26-I37 HydrophobicContact CE-CD1 3.85Å; M26-I37 HydrophobicContact CG-CD1 4.32Å; C32-I37 HydrophobicContact CB-CG2 3.58Å; R33-I37 PolarHBondContact O-N 3.47Å; E34-I37 VanDerWaalsContact O-CG1 3.31Å; E34-I37 WeakPolarHBondContact O-CG1 3.33Å; I37-R42 WeakPolarHBondContact O-CD 3.32Å; I37-P356 HydrophobicContact CB-CG 4.48Å; I37-P356 HydrophobicContact CG2-CG 3.93Å
38Q95.4Very high94.9Very high82 Ų8260.8 Ų60.838%0.38330%0.3SS..SBendtrans-68.6140.5173.5-61.7-56.3-51.200110.8E34 E36 A40 K41 R42E34-Q38 WeakPolarHBondContact O-CG 3.23Å; E34-Q38 PolarHBondContact O-NE2 3.25Å; E34-Q38 VanDerWaalsContact O-NE2 3.14Å; E36-Q38 VanDerWaalsContact C-N 3.3Å; E36-Q38 PolarHBondContact O-N 2.82Å; Q38-A40 VanDerWaalsContact C-N 3.27Å; Q38-A40 PolarHBondContact O-N 2.78Å; Q38-A40 VanDerWaalsContact O-N 3.09Å; Q38-K41 PolarHBondContact O-N 2.73Å; Q38-R42 PolarHBondContact O-N 2.83Å
39W96.9Very high95.1Very high32 Ų3259.7 Ų59.712%0.12129%0.293CS..Hα-helixtrans-47.7-45.4-176.7173.8-119.3000113.7Q19 K41 R42 W43 L46 Q67 Y71 Y72Q19-W39 HydrophobicContact CB-CE3 4.29Å; Q19-W39 HydrophobicContact CG-CB 4.05Å; W39-K41 VanDerWaalsContact C-N 3.26Å; W39-K41 PolarHBondContact O-N 3.18Å; W39-R42 PolarHBondContact O-N 2.78Å; W39-W43 HydrophobicContact CD2-CB 4.19Å; W39-W43 HydrophobicContact CE3-CB 4.41Å; W39-W43 HydrophobicContact CH2-CB 4.03Å; W39-W43 HydrophobicContact CH2-CD2 4.25Å; W39-W43 AromaticContact CH2-CE3 3.6Å; W39-W43 HydrophobicContact CH2-CE3 3.6Å; W39-W43 HydrophobicContact CH2-CG 4.45Å; W39-W43 HydrophobicContact CH2-CZ3 4.45Å; W39-W43 HydrophobicContact CZ2-CB 3.79Å; W39-W43 HydrophobicContact CZ2-CD2 4.02Å; W39-W43 AromaticContact CZ2-CE3 3.75Å; W39-W43 HydrophobicContact CZ2-CE3 3.75Å; W39-W43 HydrophobicContact CZ2-CG 4.04Å; W39-W43 HydrophobicContact CZ3-CB 4.33Å; W39-W43 VanDerWaalsContact O-CB 3.22Å; W39-W43 WeakPolarHBondContact O-CB 3.38Å; W39-W43 PolarHBondContact O-N 2.89Å; W39-L46 HydrophobicContact CZ3-CD1 4.35Å; W39-Q67 HydrophobicContact CH2-CB 4.45Å; W39-Q67 HydrophobicContact CH2-CG 4.49Å; W39-Q67 HydrophobicContact CZ2-CB 4.01Å; W39-Q67 VanDerWaalsContact CZ2-CD 3.45Å; W39-Q67 HydrophobicContact CZ2-CG 3.89Å; W39-Q67 VanDerWaalsContact CZ2-OE1 3.22Å; W39-Y71 HydrophobicContact CZ2-CD1 4.22Å; W39-Y71 AromaticContact CZ2-CD2 3.98Å; W39-Y71 HydrophobicContact CZ2-CD2 3.98Å; W39-Y71 HydrophobicContact CZ2-CE2 4.42Å; W39-Y71 AromaticContact CZ2-CG 3.88Å; W39-Y71 HydrophobicContact CZ2-CG 3.88Å; W39-Y71 AromaticContact NE1-CD2 3.91Å; W39-Y71 AromaticContact NE1-CE1 3.81Å; W39-Y71 AromaticContact NE1-CE2 3.46Å; W39-Y71 AromaticContact NE1-CZ 3.39Å; W39-Y72 AromaticContact CH2-CE2 3.8Å; W39-Y72 HydrophobicContact CH2-CE2 3.8Å; W39-Y72 AromaticContact CH2-CZ 3.94Å; W39-Y72 HydrophobicContact CZ2-CE2 4.4Å
40A96.4Very high95.3Very high74 Ų7459.3 Ų59.361%0.61229%0.292SS*.Hα-helixtrans-59.9-34.9-178.800000113.3Q38 H44Q38-A40 VanDerWaalsContact C-N 3.27Å; Q38-A40 PolarHBondContact O-N 2.78Å; Q38-A40 VanDerWaalsContact O-N 3.09Å; A40-H44 WeakPolarHBondContact O-CB 3.31Å; A40-H44 PolarHBondContact O-N 3.48Å
41K96.7Very high95.7Very high125 Ų12556 Ų5654%0.54328%0.281SS..Hα-helixtrans-79.4-45176.4-70.5-61-170.5175.10111.5S35 Q38 W39 W43 H44 A45S35-K41 VanDerWaalsContact O-CG 3.24Å; S35-K41 WeakPolarHBondContact O-CG 3.45Å; Q38-K41 PolarHBondContact O-N 2.73Å; W39-K41 VanDerWaalsContact C-N 3.26Å; W39-K41 PolarHBondContact O-N 3.18Å; K41-W43 PolarHBondContact O-N 2.8Å; K41-H44 WeakPolarHBondContact O-CB 3.32Å; K41-H44 PolarHBondContact O-N 3Å; K41-H44 VanDerWaalsContact O-N 3.16Å; K41-A45 PolarHBondContact O-N 2.73Å
42R97.6Very high95.9Very high0 Ų060.9 Ų60.90%030%0.302CS..Hα-helixtrans-58.3-47.2175.3-67.5-174.160.9-139.4-9.3112V16 L17 E36 I37 Q38 W39 H44 A45 L46 G361V16-R42 PolarHBondContact O-NH2 2.85Å; L17-R42 VanDerWaalsContact CB-NH2 3.32Å; L17-R42 VanDerWaalsContact O-CZ 3.31Å; L17-R42 PolarHBondContact O-NH1 2.93Å; L17-R42 PolarHBondContact O-NH2 3.2Å; E36-R42 WeakPolarHBondContact O-CG 3.26Å; I37-R42 WeakPolarHBondContact O-CD 3.32Å; Q38-R42 PolarHBondContact O-N 2.83Å; W39-R42 PolarHBondContact O-N 2.78Å; R42-H44 VanDerWaalsContact C-N 3.32Å; R42-H44 PolarHBondContact O-N 2.94Å; R42-A45 PolarHBondContact O-N 3.22Å; R42-L46 WeakPolarHBondContact O-CB 3.37Å; R42-L46 WeakPolarHBondContact O-CG 3.42Å; R42-L46 PolarHBondContact O-N 2.82Å; R42-G361 VanDerWaalsContact CZ-O 3.29Å; R42-G361 PolarHBondContact NE-O 2.89Å; R42-G361 PolarHBondContact NH2-O 2.95Å
43W98.2Very high96.1Very high37 Ų3761.5 Ų61.514%0.1430%0.304CS..Hα-helixtrans-59.9-41.8175.1174.1-107.5000112.1W39 K41 A45 L46 S47 F50 Y71 Y72 L75W39-W43 HydrophobicContact CD2-CB 4.19Å; W39-W43 HydrophobicContact CE3-CB 4.41Å; W39-W43 HydrophobicContact CH2-CB 4.03Å; W39-W43 HydrophobicContact CH2-CD2 4.25Å; W39-W43 AromaticContact CH2-CE3 3.6Å; W39-W43 HydrophobicContact CH2-CE3 3.6Å; W39-W43 HydrophobicContact CH2-CG 4.45Å; W39-W43 HydrophobicContact CH2-CZ3 4.45Å; W39-W43 HydrophobicContact CZ2-CB 3.79Å; W39-W43 HydrophobicContact CZ2-CD2 4.02Å; W39-W43 AromaticContact CZ2-CE3 3.75Å; W39-W43 HydrophobicContact CZ2-CE3 3.75Å; W39-W43 HydrophobicContact CZ2-CG 4.04Å; W39-W43 HydrophobicContact CZ3-CB 4.33Å; W39-W43 VanDerWaalsContact O-CB 3.22Å; W39-W43 WeakPolarHBondContact O-CB 3.38Å; W39-W43 PolarHBondContact O-N 2.89Å; K41-W43 PolarHBondContact O-N 2.8Å; W43-A45 PolarHBondContact O-N 2.99Å; W43-L46 PolarHBondContact O-N 2.92Å; W43-S47 WeakPolarHBondContact O-CB 3.34Å; W43-S47 PolarHBondContact O-N 3.19Å; W43-S47 PolarHBondContact O-OG 3.33Å; W43-S47 VanDerWaalsContact O-OG 3.1Å; W43-F50 HydrophobicContact CZ3-CE2 4.3Å; W43-Y71 AromaticContact CD1-CD1 3.59Å; W43-Y71 AromaticContact CD1-CE1 3.86Å; W43-Y71 AromaticContact CD2-CD1 3.68Å; W43-Y71 HydrophobicContact CD2-CD1 3.68Å; W43-Y71 HydrophobicContact CD2-CG 4.17Å; W43-Y71 AromaticContact CE2-CD1 3.51Å; W43-Y71 HydrophobicContact CE3-CD1 4.44Å; W43-Y71 AromaticContact CG-CD1 3.74Å; W43-Y71 HydrophobicContact CG-CD1 3.74Å; W43-Y71 HydrophobicContact CG-CE1 4.16Å; W43-Y71 VanDerWaalsContact CH2-O 3.31Å; W43-Y71 WeakPolarHBondContact CH2-O 3.38Å; W43-Y71 HydrophobicContact CZ2-CD1 4.12Å; W43-Y71 HydrophobicContact CZ2-CG 4.43Å; W43-Y71 WeakPolarHBondContact CZ2-O 3.5Å; W43-Y71 AromaticContact NE1-CD1 3.45Å; W43-Y72 HydrophobicContact CH2-CD1 4.48Å; W43-Y72 HydrophobicContact CH2-CG 4.46Å; W43-Y72 AromaticContact CZ3-CD1 3.89Å; W43-Y72 HydrophobicContact CZ3-CD1 3.89Å; W43-Y72 HydrophobicContact CZ3-CD2 4.18Å; W43-Y72 AromaticContact CZ3-CE1 3.88Å; W43-Y72 HydrophobicContact CZ3-CE1 3.88Å; W43-Y72 HydrophobicContact CZ3-CE2 4.17Å; W43-Y72 HydrophobicContact CZ3-CG 4.05Å; W43-L75 HydrophobicContact CH2-CB 4.09Å; W43-L75 HydrophobicContact CH2-CD2 3.76Å; W43-L75 HydrophobicContact CZ2-CB 4.06Å; W43-L75 HydrophobicContact CZ2-CD2 3.9Å
44H97.9Very high96.4Very high109 Ų10957.5 Ų57.551%0.50530%0.295SS..Hα-helixtrans-58.5-49.3175.9-178.467.5000110.8A40 K41 R42 S47 Q48A40-H44 WeakPolarHBondContact O-CB 3.31Å; A40-H44 PolarHBondContact O-N 3.48Å; K41-H44 WeakPolarHBondContact O-CB 3.32Å; K41-H44 PolarHBondContact O-N 3Å; K41-H44 VanDerWaalsContact O-N 3.16Å; R42-H44 VanDerWaalsContact C-N 3.32Å; R42-H44 PolarHBondContact O-N 2.94Å; H44-S47 PolarHBondContact O-N 3.43Å; H44-S47 PolarHBondContact O-OG 3.1Å; H44-Q48 WeakPolarHBondContact O-CG 3.33Å; H44-Q48 PolarHBondContact O-N 3.28Å; H44-Q48 VanDerWaalsContact O-N 3.17Å
45A97.4Very high96.9Very high4 Ų451.2 Ų51.23%0.03327%0.265CS..Hα-helixtrans-59.8-54.3175.900000112.2K41 R42 W43 S47 Q48 E49K41-A45 PolarHBondContact O-N 2.73Å; R42-A45 PolarHBondContact O-N 3.22Å; W43-A45 PolarHBondContact O-N 2.99Å; A45-S47 VanDerWaalsContact C-N 3.3Å; A45-S47 PolarHBondContact O-N 3.44Å; A45-Q48 PolarHBondContact O-N 3.05Å; A45-E49 WeakPolarHBondContact O-CG 3.46Å; A45-E49 PolarHBondContact O-N 3.49Å
46L98.4Very high97.2Very high0 Ų047.8 Ų47.80%024%0.241CC..Hα-helixtrans-53.5-45.6178.1-72.7173.8000112.2Y14 V16 W39 R42 W43 Q48 E49 F50Y14-L46 HydrophobicContact CE1-CD2 3.89Å; V16-L46 HydrophobicContact CB-CD1 4.25Å; V16-L46 HydrophobicContact CB-CD2 4.3Å; V16-L46 HydrophobicContact CG1-CD2 4.33Å; W39-L46 HydrophobicContact CZ3-CD1 4.35Å; R42-L46 WeakPolarHBondContact O-CB 3.37Å; R42-L46 WeakPolarHBondContact O-CG 3.42Å; R42-L46 PolarHBondContact O-N 2.82Å; W43-L46 PolarHBondContact O-N 2.92Å; L46-Q48 VanDerWaalsContact C-N 3.32Å; L46-Q48 PolarHBondContact O-N 3.04Å; L46-E49 WeakPolarHBondContact O-CB 3.47Å; L46-E49 PolarHBondContact O-N 3.26Å; L46-F50 HydrophobicContact CB-CE2 3.87Å; L46-F50 HydrophobicContact CB-CZ 4.07Å; L46-F50 HydrophobicContact CD2-CZ 4.28Å; L46-F50 WeakPolarHBondContact O-CD2 3.38Å; L46-F50 WeakPolarHBondContact O-CG 3.47Å; L46-F50 PolarHBondContact O-N 3.36Å
47S98.4Very high97.6Very high13 Ų1346.4 Ų46.49%0.09124%0.235CC..Hα-helixtrans-63-37.9-179.771.10000112.5W43 H44 A45 V51W43-S47 WeakPolarHBondContact O-CB 3.34Å; W43-S47 PolarHBondContact O-N 3.19Å; W43-S47 PolarHBondContact O-OG 3.33Å; W43-S47 VanDerWaalsContact O-OG 3.1Å; H44-S47 PolarHBondContact O-N 3.43Å; H44-S47 PolarHBondContact O-OG 3.1Å; A45-S47 VanDerWaalsContact C-N 3.3Å; A45-S47 PolarHBondContact O-N 3.44Å; S47-V51 VanDerWaalsContact O-CG2 3.28Å; S47-V51 WeakPolarHBondContact O-CG2 3.45Å; S47-V51 PolarHBondContact O-N 3.1Å
48Q98.1Very high97.8Very high109 Ų10946.2 Ų46.251%0.50923%0.233SC..Hα-helixtrans-69.7-41.1174.4-66.1-57.7-58.600111.1H44 A45 L46 F50 V51 H52H44-Q48 WeakPolarHBondContact O-CG 3.33Å; H44-Q48 PolarHBondContact O-N 3.28Å; H44-Q48 VanDerWaalsContact O-N 3.17Å; A45-Q48 PolarHBondContact O-N 3.05Å; L46-Q48 VanDerWaalsContact C-N 3.32Å; L46-Q48 PolarHBondContact O-N 3.04Å; Q48-F50 PolarHBondContact O-N 2.78Å; Q48-V51 PolarHBondContact O-N 2.93Å; Q48-H52 WeakPolarHBondContact O-CB 3.48Å; Q48-H52 PolarHBondContact O-N 2.94Å
49E97.2Very high98Very high26 Ų2642.3 Ų42.312%0.12122%0.215CC..Hα-helixtrans-58.5-47.1175.3-70.9176.2-105.200111.3Y14 A45 L46 V51 H52 L53 C360 G361Y14-E49 WeakPolarHBondContact CE1-OE2 3.37Å; Y14-E49 PolarHBondContact OH-OE1 2.84Å; Y14-E49 PolarHBondContact OH-OE2 2.89Å; A45-E49 WeakPolarHBondContact O-CG 3.46Å; A45-E49 PolarHBondContact O-N 3.49Å; L46-E49 WeakPolarHBondContact O-CB 3.47Å; L46-E49 PolarHBondContact O-N 3.26Å; E49-V51 VanDerWaalsContact C-N 3.35Å; E49-V51 PolarHBondContact O-N 3.48Å; E49-H52 PolarHBondContact O-N 2.79Å; E49-L53 VanDerWaalsContact O-CB 3.31Å; E49-L53 WeakPolarHBondContact O-CB 3.46Å; E49-L53 WeakPolarHBondContact O-CG 2.95Å; E49-L53 PolarHBondContact O-N 2.79Å; E49-C360 WeakPolarHBondContact OE1-CA 3.17Å; E49-G361 PolarHBondContact OE1-N 2.7Å
50F98.6Very high98.1Very high1 Ų140.8 Ų40.80%0.00421%0.209CC..Hα-helixtrans-61.2-42.7178.2-58-40.4000112.4Y14 V16 W43 L46 Q48 H52 D54 F58 L60 Y72 L75 F76Y14-F50 AromaticContact CD1-CE1 3.84Å; Y14-F50 HydrophobicContact CD1-CE1 3.84Å; Y14-F50 HydrophobicContact CE1-CE1 4.19Å; V16-F50 HydrophobicContact CG1-CE1 4.21Å; V16-F50 HydrophobicContact CG1-CZ 3.84Å; W43-F50 HydrophobicContact CZ3-CE2 4.3Å; L46-F50 HydrophobicContact CB-CE2 3.87Å; L46-F50 HydrophobicContact CB-CZ 4.07Å; L46-F50 HydrophobicContact CD2-CZ 4.28Å; L46-F50 WeakPolarHBondContact O-CD2 3.38Å; L46-F50 WeakPolarHBondContact O-CG 3.47Å; L46-F50 PolarHBondContact O-N 3.36Å; Q48-F50 PolarHBondContact O-N 2.78Å; F50-H52 VanDerWaalsContact C-N 3.34Å; F50-D54 PolarHBondContact O-N 3.48Å; F50-F58 HydrophobicContact CB-CZ 4.42Å; F50-F58 HydrophobicContact CD1-CD1 4.25Å; F50-F58 AromaticContact CD1-CE1 3.93Å; F50-F58 HydrophobicContact CD1-CE1 3.93Å; F50-L60 HydrophobicContact CE1-CD1 4.24Å; F50-L60 HydrophobicContact CE1-CD2 3.95Å; F50-L60 HydrophobicContact CZ-CD1 4.06Å; F50-L60 HydrophobicContact CZ-CD2 4.47Å; F50-Y72 HydrophobicContact CE2-CD1 4.27Å; F50-Y72 HydrophobicContact CE2-CE1 4.08Å; F50-Y72 HydrophobicContact CZ-CE1 4.17Å; F50-L75 HydrophobicContact CD2-CD2 3.96Å; F50-F76 HydrophobicContact CB-CZ 4.25Å; F50-F76 HydrophobicContact CD1-CZ 4.27Å; F50-F76 HydrophobicContact CD2-CE2 4.18Å; F50-F76 HydrophobicContact CD2-CZ 4.19Å; F50-F76 HydrophobicContact CE2-CE2 4.42Å; F50-F76 HydrophobicContact CG-CE2 4.44Å; F50-F76 AromaticContact CG-CZ 3.99Å; F50-F76 HydrophobicContact CG-CZ 3.99Å
51V98.4Very high98.2Very high68 Ų6837.2 Ų37.241%0.41218%0.18SC..Hα-helixtrans-64.8-39.8177171.80000111.3S47 Q48 E49 L79S47-V51 VanDerWaalsContact O-CG2 3.28Å; S47-V51 WeakPolarHBondContact O-CG2 3.45Å; S47-V51 PolarHBondContact O-N 3.1Å; Q48-V51 PolarHBondContact O-N 2.93Å; E49-V51 VanDerWaalsContact C-N 3.35Å; E49-V51 PolarHBondContact O-N 3.48Å; V51-L79 HydrophobicContact CG2-CD1 3.9Å; V51-L79 HydrophobicContact CG2-CD2 4.14Å
52H97.8Very high98.3Very high167 Ų16732.2 Ų32.277%0.77316%0.159SC*.Hα-helixtrans-73-41.7-179.5-174.370.9000112.7Q48 E49 F50 D54Q48-H52 WeakPolarHBondContact O-CB 3.48Å; Q48-H52 PolarHBondContact O-N 2.94Å; E49-H52 PolarHBondContact O-N 2.79Å; F50-H52 VanDerWaalsContact C-N 3.34Å; H52-D54 VanDerWaalsContact C-N 3.33Å
53L97.9Very high98.3Very high32 Ų3232.2 Ų32.217%0.16816%0.159CC..Hα-helixtrans-66.1-35.9177.8-71167.3000111.6E49 A55 F58 P366 L368E49-L53 VanDerWaalsContact O-CB 3.31Å; E49-L53 WeakPolarHBondContact O-CB 3.46Å; E49-L53 WeakPolarHBondContact O-CG 2.95Å; E49-L53 PolarHBondContact O-N 2.79Å; L53-A55 PolarHBondContact O-N 2.96Å; L53-F58 HydrophobicContact CB-CE1 4.14Å; L53-F58 HydrophobicContact CB-CZ 3.95Å; L53-F58 HydrophobicContact CD1-CE1 4.17Å; L53-P366 HydrophobicContact CD1-CB 3.95Å; L53-P366 HydrophobicContact CD1-CG 4.03Å; L53-P366 HydrophobicContact CD2-CG 4.46Å; L53-L368 HydrophobicContact CD2-CD2 4.13Å
54D98.2Very high98.3Very high84 Ų8430.7 Ų30.745%0.44915%0.153SC..  trans4336.7178.4-169.836000114.5F50 H52 Y81 K101F50-D54 PolarHBondContact O-N 3.48Å; H52-D54 VanDerWaalsContact C-N 3.33Å; D54-Y81 PolarHBondContact OD1-OH 2.79Å; D54-K101 PolarHBondContact O-NZ 2.8Å; D54-K101 WeakPolarHBondContact OD1-CE 3.37Å; D54-K101 IonicContact OD1-NZ 3.53Å; D54-K101 PolarHBondContact OD1-NZ 3.04Å; D54-K101 IonicContact OD2-NZ 3.47Å; D54-K101 PolarHBondContact OD2-NZ 2.82Å
55A98.7Very high98.3Very high0 Ų026.5 Ų26.50%014%0.137CC..  trans-67.1140.4-175.900000110.9T10 C12 L53 I57 F58 Y81 L368T10-A55 WeakPolarHBondContact OG1-CA 3.16Å; C12-A55 HydrophobicContact CB-CB 3.55Å; L53-A55 PolarHBondContact O-N 2.96Å; A55-I57 PolarHBondContact O-N 2.65Å; A55-F58 HydrophobicContact CB-CD1 4.39Å; A55-F58 HydrophobicContact CB-CD2 4.04Å; A55-F58 HydrophobicContact CB-CE1 4.01Å; A55-F58 HydrophobicContact CB-CE2 3.64Å; A55-F58 HydrophobicContact CB-CG 4.41Å; A55-F58 HydrophobicContact CB-CZ 3.63Å; A55-F58 VanDerWaalsContact O-CE2 3.29Å; A55-F58 WeakPolarHBondContact O-CE2 3.35Å; A55-Y81 WeakPolarHBondContact O-CE1 3.19Å; A55-Y81 PolarHBondContact O-OH 2.85Å; A55-L368 HydrophobicContact CB-CD1 3.65Å
56D98.8Very high98.2Very high7 Ų731.7 Ų31.74%0.03717%0.165CC..SBendtrans-69.3-24.6-177.1-57.4-59.2000113.3F9 T10 W100 K101 K104 F105F9-D56 WeakPolarHBondContact CA-OD2 3.24Å; F9-D56 HydrophobicContact CB-CB 4.15Å; T10-D56 PolarHBondContact N-OD2 3.16Å; T10-D56 WeakPolarHBondContact O-CB 3.47Å; T10-D56 PolarHBondContact O-N 3.39Å; T10-D56 VanDerWaalsContact O-N 3.13Å; T10-D56 PolarHBondContact OG1-N 2.74Å; T10-D56 PolarHBondContact OG1-OD2 3.33Å; D56-W100 CarbonylContact O-C 3.59Å; D56-W100 WeakPolarHBondContact O-CA 3.38Å; D56-K101 HydrophobicContact CB-CD 4.47Å; D56-K101 PolarHBondContact O-N 2.67Å; D56-K101 WeakPolarHBondContact OD1-CD 3.47Å; D56-K101 IonicContact OD1-NZ 3.4Å; D56-K101 PolarHBondContact OD1-NZ 2.82Å; D56-K104 HydrophobicContact CB-CD 3.99Å; D56-K104 WeakPolarHBondContact OD1-CD 3.32Å; D56-K104 VanDerWaalsContact OD1-CE 3.26Å; D56-K104 WeakPolarHBondContact OD1-CE 3.42Å; D56-K104 IonicContact OD1-NZ 2.72Å; D56-K104 PolarHBondContact OD1-NZ 3.16Å; D56-K104 IonicContact OD2-NZ 3.56Å; D56-K104 PolarHBondContact OD2-NZ 3.32Å; D56-F105 HydrophobicContact CB-CE2 4.03Å
57I98.9Very high98.2Very high0 Ų032.4 Ų32.40%017%0.168CC..EExtended strand (participates in β ladder)trans-132.5131.1170.9-59174.7000108.7F9 T10 L11 C12 A55 T98 F99 W100 F105 L133 V153F9-I57 HydrophobicContact CD2-CD1 4.2Å; F9-I57 HydrophobicContact CE2-CD1 4.1Å; T10-I57 PolarHBondContact O-N 3.48Å; L11-I57 CarbonylContact C-O 3.53Å; L11-I57 VanDerWaalsContact CA-O 3.29Å; L11-I57 WeakPolarHBondContact CA-O 3.24Å; L11-I57 HydrophobicContact CB-CB 4.3Å; L11-I57 HydrophobicContact CD1-CB 4.06Å; L11-I57 HydrophobicContact CD1-CD1 4.4Å; L11-I57 HydrophobicContact CD1-CG2 3.79Å; L11-I57 HydrophobicContact CG-CB 4.04Å; L11-I57 HydrophobicContact CG-CG2 4.03Å; C12-I57 PolarHBondContact N-O 3.02Å; A55-I57 PolarHBondContact O-N 2.65Å; I57-T98 HydrophobicContact CG2-CG2 4.12Å; I57-F99 CarbonylContact C-O 3.51Å; I57-F99 VanDerWaalsContact CA-O 3.22Å; I57-F99 WeakPolarHBondContact CA-O 3.4Å; I57-F99 WeakPolarHBondContact CG2-O 3.34Å; I57-W100 HydrophobicContact CG1-CB 4.09Å; I57-F105 HydrophobicContact CD1-CD2 4.32Å; I57-F105 HydrophobicContact CD1-CE1 4.11Å; I57-F105 HydrophobicContact CD1-CE2 3.87Å; I57-F105 HydrophobicContact CD1-CZ 3.76Å; I57-F105 HydrophobicContact CG1-CD2 4.11Å; I57-F105 HydrophobicContact CG1-CE2 3.73Å; I57-F105 HydrophobicContact CG1-CZ 4.14Å; I57-L133 HydrophobicContact CD1-CD1 3.86Å; I57-L133 HydrophobicContact CG1-CD1 4.46Å; I57-V153 HydrophobicContact CD1-CG2 4.15Å; I57-V153 HydrophobicContact CG2-CG1 4.48Å
58F98.9Very high98.1Very high0 Ų032.4 Ų32.40%017%0.167CC..EExtended strand (participates in β ladder)trans-112.4127.6168.9-76.7-90.6000110.1C12 F50 L53 A55 L60 F76 Y81 T98 F99C12-F58 HydrophobicContact CB-CD1 3.58Å; C12-F58 HydrophobicContact CB-CE1 3.72Å; C12-F58 HydrophobicContact CB-CG 4.32Å; C12-F58 CarbonylContact O-C 3.57Å; C12-F58 WeakPolarHBondContact O-CA 3.41Å; F50-F58 HydrophobicContact CB-CZ 4.42Å; F50-F58 HydrophobicContact CD1-CD1 4.25Å; F50-F58 AromaticContact CD1-CE1 3.93Å; F50-F58 HydrophobicContact CD1-CE1 3.93Å; L53-F58 HydrophobicContact CB-CE1 4.14Å; L53-F58 HydrophobicContact CB-CZ 3.95Å; L53-F58 HydrophobicContact CD1-CE1 4.17Å; A55-F58 HydrophobicContact CB-CD1 4.39Å; A55-F58 HydrophobicContact CB-CD2 4.04Å; A55-F58 HydrophobicContact CB-CE1 4.01Å; A55-F58 HydrophobicContact CB-CE2 3.64Å; A55-F58 HydrophobicContact CB-CG 4.41Å; A55-F58 HydrophobicContact CB-CZ 3.63Å; A55-F58 VanDerWaalsContact O-CE2 3.29Å; A55-F58 WeakPolarHBondContact O-CE2 3.35Å; F58-L60 HydrophobicContact CB-CD2 4.11Å; F58-L60 HydrophobicContact CB-CG 4.31Å; F58-L60 HydrophobicContact CD1-CD2 4.15Å; F58-F76 HydrophobicContact CB-CE1 4.28Å; F58-F76 HydrophobicContact CB-CZ 4.21Å; F58-F76 AromaticContact CD2-CE1 3.48Å; F58-F76 HydrophobicContact CD2-CE1 3.48Å; F58-F76 VanDerWaalsContact CD2-CE1 3.48Å; F58-F76 AromaticContact CD2-CZ 3.98Å; F58-F76 HydrophobicContact CD2-CZ 3.98Å; F58-F76 AromaticContact CE2-CE1 3.91Å; F58-F76 HydrophobicContact CE2-CE1 3.91Å; F58-F76 HydrophobicContact CE2-CZ 4.45Å; F58-F76 AromaticContact CG-CE1 3.96Å; F58-F76 HydrophobicContact CG-CE1 3.96Å; F58-F76 HydrophobicContact CG-CZ 4Å; F58-Y81 AromaticContact CD2-CE1 3.91Å; F58-Y81 HydrophobicContact CD2-CE1 3.91Å; F58-Y81 HydrophobicContact CE2-CE1 4.15Å; F58-T98 CarbonylContact O-C 3.57Å; F58-T98 VanDerWaalsContact O-CA 3.24Å; F58-T98 WeakPolarHBondContact O-CA 3.44Å; F58-F99 HydrophobicContact CB-CB 4.34Å; F58-F99 PolarHBondContact N-O 2.78Å; F58-F99 PolarHBondContact O-N 3.16Å
59C99Very high98Very high0 Ų032.4 Ų32.40%017%0.17CC..EExtended strand (participates in β ladder)trans-109.5102.6169.6-70.60000108.1C12 S13 Y14 Q61 V153 N155 C196C12-C59 PolarHBondContact O-N 2.65Å; S13-C59 CarbonylContact C-O 3.49Å; S13-C59 WeakPolarHBondContact CA-O 3.31Å; Y14-C59 PolarHBondContact N-O 2.81Å; C59-Q61 PolarHBondContact O-NE2 2.65Å; C59-V153 WeakPolarHBondContact SG-CG1 3.35Å; C59-N155 HydrophobicContact CB-CB 3.95Å; C59-C196 WeakPolarHBondContact CB-SG 3.21Å
60L98.9Very high98Very high0 Ų033.9 Ų33.90%018%0.183CC..EExtended strand (participates in β ladder)trans-102.5135.7-175.7-51.8-176.5000111Y14 V16 F50 F58 V63 Y72 F76 C96 A97 F99 N155Y14-L60 VanDerWaalsContact O-CA 3.26Å; Y14-L60 WeakPolarHBondContact O-CA 3.27Å; V16-L60 HydrophobicContact CG1-CB 4.32Å; V16-L60 HydrophobicContact CG1-CD1 4.37Å; V16-L60 HydrophobicContact CG1-CD2 4.05Å; V16-L60 HydrophobicContact CG1-CG 4.48Å; F50-L60 HydrophobicContact CE1-CD1 4.24Å; F50-L60 HydrophobicContact CE1-CD2 3.95Å; F50-L60 HydrophobicContact CZ-CD1 4.06Å; F50-L60 HydrophobicContact CZ-CD2 4.47Å; F58-L60 HydrophobicContact CB-CD2 4.11Å; F58-L60 HydrophobicContact CB-CG 4.31Å; F58-L60 HydrophobicContact CD1-CD2 4.15Å; L60-V63 HydrophobicContact CB-CG2 3.52Å; L60-V63 HydrophobicContact CD1-CG2 4.3Å; L60-Y72 HydrophobicContact CD1-CD1 4.03Å; L60-Y72 HydrophobicContact CD1-CE1 4.27Å; L60-F76 HydrophobicContact CD1-CE2 3.94Å; L60-F76 HydrophobicContact CD1-CZ 4.25Å; L60-C96 CarbonylContact O-C 3.57Å; L60-C96 VanDerWaalsContact O-CA 3.27Å; L60-C96 WeakPolarHBondContact O-CA 3.49Å; L60-A97 HydrophobicContact CB-CB 4.4Å; L60-A97 PolarHBondContact N-O 3.5Å; L60-A97 PolarHBondContact O-N 2.84Å; L60-F99 HydrophobicContact CD1-CD2 4.09Å; L60-F99 HydrophobicContact CD1-CE2 3.9Å; L60-N155 PolarHBondContact N-ND2 2.83Å; L60-N155 PolarHBondContact O-ND2 2.92Å
61Q98.7Very high98Very high0 Ų038.1 Ų38.10%020%0.2CC..EExtended strand (participates in β ladder)trans-109.7156.9172.9-56.776.447.300110.1S13 Y14 N15 V16 C59 V63 N155 T156 H157 D198S13-Q61 PolarHBondContact OG-NE2 3.34Å; Y14-Q61 PolarHBondContact O-N 2.84Å; Y14-Q61 PolarHBondContact O-OE1 2.92Å; N15-Q61 HydrophobicContact CB-CB 4.1Å; V16-Q61 VanDerWaalsContact CG2-O 3.23Å; V16-Q61 WeakPolarHBondContact CG2-O 3.29Å; V16-Q61 PolarHBondContact N-O 2.85Å; C59-Q61 PolarHBondContact O-NE2 2.65Å; Q61-V63 PolarHBondContact O-N 2.94Å; Q61-N155 PolarHBondContact NE2-OD1 3.38Å; Q61-T156 WeakPolarHBondContact CG-O 3.44Å; Q61-H157 HydrophobicContact CB-CB 4.03Å; Q61-H157 HydrophobicContact CG-CB 4.04Å; Q61-D198 HydrophobicContact CG-CB 4.41Å
62E98.4Very high98Very high20 Ų2035 Ų359%0.09318%0.18CC..EExtended strand (participates in β ladder)trans5830.2-177.3-59.3-162.6-158.800115.5N15 C18 Q64 G95 H157N15-E62 PolarHBondContact ND2-OE1 2.95Å; N15-E62 VanDerWaalsContact ND2-OE1 3.1Å; N15-E62 VanDerWaalsContact OD1-CB 3.31Å; N15-E62 WeakPolarHBondContact OD1-CB 3.49Å; N15-E62 WeakPolarHBondContact OD1-CG 3.19Å; C18-E62 WeakPolarHBondContact CA-O 3.34Å; C18-E62 HydrophobicContact CB-CB 4.02Å; C18-E62 WeakPolarHBondContact CB-O 3.41Å; C18-E62 PolarHBondContact N-O 3.15Å; C18-E62 PolarHBondContact N-OE2 3.31Å; E62-Q64 PolarHBondContact O-N 2.85Å; E62-G95 PolarHBondContact N-O 3.09Å; E62-H157 WeakPolarHBondContact CG-ND1 3.39Å; E62-H157 IonicContact OE1-CE1 2.82Å; E62-H157 PolarHBondContact OE1-CE1 3.22Å; E62-H157 IonicContact OE1-ND1 2.92Å
63V98.7Very high98Very high0 Ų030.2 Ų30.20%016%0.159CC..EExtended strand (participates in β ladder)trans-70.4118.5173.9179.60000108.8V16 L60 Q61 F68 Y72 Y85 D94 G95 A97V16-V63 HydrophobicContact CG2-CG2 3.83Å; L60-V63 HydrophobicContact CB-CG2 3.52Å; L60-V63 HydrophobicContact CD1-CG2 4.3Å; Q61-V63 PolarHBondContact O-N 2.94Å; V63-F68 HydrophobicContact CG1-CB 4.36Å; V63-F68 HydrophobicContact CG1-CD2 3.92Å; V63-Y72 HydrophobicContact CG1-CD1 4.3Å; V63-Y72 HydrophobicContact CG1-CD2 3.75Å; V63-Y72 HydrophobicContact CG1-CE1 4.39Å; V63-Y72 HydrophobicContact CG1-CE2 3.86Å; V63-Y72 HydrophobicContact CG1-CG 3.98Å; V63-Y72 HydrophobicContact CG2-CE1 4.46Å; V63-Y85 HydrophobicContact CB-CD2 4.41Å; V63-Y85 HydrophobicContact CB-CE2 4.01Å; V63-Y85 HydrophobicContact CG1-CD2 4.4Å; V63-Y85 HydrophobicContact CG1-CE2 4.17Å; V63-Y85 PolarHBondContact O-OH 2.96Å; V63-D94 CarbonylContact O-C 3.52Å; V63-D94 VanDerWaalsContact O-CA 3.26Å; V63-D94 WeakPolarHBondContact O-CA 3.2Å; V63-G95 PolarHBondContact N-O 2.82Å; V63-G95 PolarHBondContact O-N 3.43Å; V63-A97 HydrophobicContact CB-CB 4.48Å; V63-A97 HydrophobicContact CG2-CB 3.95Å
64Q98Very high98Very high4 Ų434.5 Ų34.52%0.01918%0.176CC..EExtended strand (participates in β ladder)trans-70.1133.6-179.4-167169.6-55.300111.5C18 Q19 D20 E62 D66 Q67 F68 A93C18-Q64 PolarHBondContact SG-OE1 2.8Å; Q19-Q64 VanDerWaalsContact CB-OE1 3.32Å; Q19-Q64 VanDerWaalsContact N-OE1 3.14Å; D20-Q64 PolarHBondContact OD1-NE2 2.87Å; D20-Q64 PolarHBondContact OD1-OE1 3.43Å; E62-Q64 PolarHBondContact O-N 2.85Å; Q64-D66 VanDerWaalsContact CG-OD1 3.24Å; Q64-D66 WeakPolarHBondContact CG-OD1 3.22Å; Q64-D66 PolarHBondContact NE2-OD1 2.84Å; Q64-D66 PolarHBondContact O-N 3.04Å; Q64-Q67 HydrophobicContact CB-CB 4.26Å; Q64-Q67 HydrophobicContact CB-CG 4.26Å; Q64-Q67 HydrophobicContact CG-CG 4.5Å; Q64-Q67 PolarHBondContact O-N 2.85Å; Q64-F68 PolarHBondContact O-N 2.8Å; Q64-A93 HydrophobicContact CG-CB 4.41Å
65A97.1Very high98.1Very high21 Ų2131.5 Ų31.517%0.17416%0.16CC..Hα-helixtrans-64.5-43-168.600000113.8Q67 F68 Y85 R87 A93A65-Q67 PolarHBondContact O-N 2.92Å; A65-F68 PolarHBondContact O-N 3.13Å; A65-Y85 WeakPolarHBondContact CA-OH 3.24Å; A65-Y85 HydrophobicContact CB-CE1 4.33Å; A65-Y85 WeakPolarHBondContact CB-OH 3.46Å; A65-R87 HydrophobicContact CB-CG 4.09Å; A65-A93 VanDerWaalsContact CB-O 3.29Å; A65-A93 WeakPolarHBondContact CB-O 3.45Å; A65-A93 PolarHBondContact N-O 3.15Å
66D95.7Very high98.1Very high114 Ų11431.5 Ų31.561%0.6116%0.16SC*.Hα-helixtrans-76-13.6179.964.6-11.8000113.2Q64 S70Q64-D66 VanDerWaalsContact CG-OD1 3.24Å; Q64-D66 WeakPolarHBondContact CG-OD1 3.22Å; Q64-D66 PolarHBondContact NE2-OD1 2.84Å; Q64-D66 PolarHBondContact O-N 3.04Å; D66-S70 PolarHBondContact O-OG 3.3Å
67Q96.9Very high98.1Very high15 Ų1534.7 Ų34.77%0.0718%0.177CC..Hα-helixtrans-94.8-16.7174.7-64.8169-0.200112.5W39 Q64 A65 S70 Y71 Y72W39-Q67 HydrophobicContact CH2-CB 4.45Å; W39-Q67 HydrophobicContact CH2-CG 4.49Å; W39-Q67 HydrophobicContact CZ2-CB 4.01Å; W39-Q67 VanDerWaalsContact CZ2-CD 3.45Å; W39-Q67 HydrophobicContact CZ2-CG 3.89Å; W39-Q67 VanDerWaalsContact CZ2-OE1 3.22Å; Q64-Q67 HydrophobicContact CB-CB 4.26Å; Q64-Q67 HydrophobicContact CB-CG 4.26Å; Q64-Q67 HydrophobicContact CG-CG 4.5Å; Q64-Q67 PolarHBondContact O-N 2.85Å; A65-Q67 PolarHBondContact O-N 2.92Å; Q67-S70 PolarHBondContact O-OG 2.85Å; Q67-Y71 HydrophobicContact CB-CD2 4.03Å; Q67-Y71 HydrophobicContact CG-CD2 4.26Å; Q67-Y71 WeakPolarHBondContact O-CB 3.31Å; Q67-Y71 PolarHBondContact O-N 2.83Å; Q67-Y72 HydrophobicContact CB-CD2 4.39Å; Q67-Y72 HydrophobicContact CB-CE2 4.11Å; Q67-Y72 PolarHBondContact O-N 3.26Å
68F97.9Very high98Very high13 Ų1341.1 Ų41.16%0.05721%0.207CC..Iπ-helixtrans-57-60.8-173.7177.6-103.1000112.2V63 Q64 A65 S70 Y72 E73 Y85 A97 F99V63-F68 HydrophobicContact CG1-CB 4.36Å; V63-F68 HydrophobicContact CG1-CD2 3.92Å; Q64-F68 PolarHBondContact O-N 2.8Å; A65-F68 PolarHBondContact O-N 3.13Å; F68-S70 PolarHBondContact O-N 2.99Å; F68-Y72 PolarHBondContact O-N 2.97Å; F68-Y72 VanDerWaalsContact O-N 3.1Å; F68-E73 HydrophobicContact CD1-CB 4.45Å; F68-E73 HydrophobicContact CE1-CB 4.01Å; F68-E73 HydrophobicContact CE1-CG 4.37Å; F68-E73 HydrophobicContact CZ-CB 4.07Å; F68-E73 HydrophobicContact CZ-CG 4.43Å; F68-E73 PolarHBondContact O-N 2.88Å; F68-Y85 HydrophobicContact CB-CD1 4.42Å; F68-Y85 HydrophobicContact CB-CE1 4.48Å; F68-Y85 HydrophobicContact CD1-CD1 4.05Å; F68-Y85 HydrophobicContact CD1-CG 4.11Å; F68-Y85 HydrophobicContact CD2-CD1 4.39Å; F68-Y85 AromaticContact CD2-CD2 3.92Å; F68-Y85 HydrophobicContact CD2-CD2 3.92Å; F68-Y85 AromaticContact CD2-CG 3.78Å; F68-Y85 HydrophobicContact CD2-CG 3.78Å; F68-Y85 HydrophobicContact CE1-CG 4.29Å; F68-Y85 VanDerWaalsContact CE2-CB 3.43Å; F68-Y85 HydrophobicContact CE2-CD2 4.26Å; F68-Y85 AromaticContact CE2-CG 3.96Å; F68-Y85 HydrophobicContact CE2-CG 3.96Å; F68-Y85 HydrophobicContact CG-CD1 4Å; F68-Y85 HydrophobicContact CG-CD2 4.3Å; F68-Y85 AromaticContact CG-CG 3.87Å; F68-Y85 HydrophobicContact CG-CG 3.87Å; F68-Y85 HydrophobicContact CZ-CG 4.22Å; F68-A97 HydrophobicContact CD2-CB 4.44Å; F68-A97 HydrophobicContact CE2-CB 3.97Å; F68-F99 HydrophobicContact CD2-CZ 4.35Å; F68-F99 HydrophobicContact CE2-CE1 4.12Å; F68-F99 HydrophobicContact CE2-CE2 4.27Å; F68-F99 AromaticContact CE2-CZ 3.47Å; F68-F99 HydrophobicContact CE2-CZ 3.47Å; F68-F99 VanDerWaalsContact CE2-CZ 3.47Å; F68-F99 HydrophobicContact CZ-CE1 4.32Å; F68-F99 HydrophobicContact CZ-CZ 4.11Å
69D96Very high98Very high108 Ų10844.4 Ų44.458%0.57822%0.224SC*.Iπ-helixtrans-64.6-43.6-176.6-59.3-29.5000111.7K74D69-K74 PolarHBondContact O-N 3.29Å
70S96Very high98Very high57 Ų5746.2 Ų46.240%0.39924%0.243SC..Iπ-helixtrans-76.8-29-16955.40000113.8D66 Q67 F68 K74D66-S70 PolarHBondContact O-OG 3.3Å; Q67-S70 PolarHBondContact O-OG 2.85Å; F68-S70 PolarHBondContact O-N 2.99Å; S70-K74 WeakPolarHBondContact O-CD 3.16Å
71Y98.4Very high98Very high90 Ų9046.4 Ų46.435%0.35324%0.244SC..Iπ-helixtrans-117.7-64.5-177.1-67.4-86.3000112W39 W43 Q67 L75W39-Y71 HydrophobicContact CZ2-CD1 4.22Å; W39-Y71 AromaticContact CZ2-CD2 3.98Å; W39-Y71 HydrophobicContact CZ2-CD2 3.98Å; W39-Y71 HydrophobicContact CZ2-CE2 4.42Å; W39-Y71 AromaticContact CZ2-CG 3.88Å; W39-Y71 HydrophobicContact CZ2-CG 3.88Å; W39-Y71 AromaticContact NE1-CD2 3.91Å; W39-Y71 AromaticContact NE1-CE1 3.81Å; W39-Y71 AromaticContact NE1-CE2 3.46Å; W39-Y71 AromaticContact NE1-CZ 3.39Å; W43-Y71 AromaticContact CD1-CD1 3.59Å; W43-Y71 AromaticContact CD1-CE1 3.86Å; W43-Y71 AromaticContact CD2-CD1 3.68Å; W43-Y71 HydrophobicContact CD2-CD1 3.68Å; W43-Y71 HydrophobicContact CD2-CG 4.17Å; W43-Y71 AromaticContact CE2-CD1 3.51Å; W43-Y71 HydrophobicContact CE3-CD1 4.44Å; W43-Y71 AromaticContact CG-CD1 3.74Å; W43-Y71 HydrophobicContact CG-CD1 3.74Å; W43-Y71 HydrophobicContact CG-CE1 4.16Å; W43-Y71 VanDerWaalsContact CH2-O 3.31Å; W43-Y71 WeakPolarHBondContact CH2-O 3.38Å; W43-Y71 HydrophobicContact CZ2-CD1 4.12Å; W43-Y71 HydrophobicContact CZ2-CG 4.43Å; W43-Y71 WeakPolarHBondContact CZ2-O 3.5Å; W43-Y71 AromaticContact NE1-CD1 3.45Å; Q67-Y71 HydrophobicContact CB-CD2 4.03Å; Q67-Y71 HydrophobicContact CG-CD2 4.26Å; Q67-Y71 WeakPolarHBondContact O-CB 3.31Å; Q67-Y71 PolarHBondContact O-N 2.83Å; Y71-L75 WeakPolarHBondContact O-CB 2.94Å; Y71-L75 PolarHBondContact O-N 2.94Å
72Y98.7Very high98Very high2 Ų251.8 Ų51.81%0.00827%0.267CS..Iπ-helixtrans-66.7-60.2-171.7-65.7-93000111.6V16 W39 W43 F50 L60 V63 Q67 F68 K74 L75 F76V16-Y72 HydrophobicContact CG2-CE1 4.12Å; V16-Y72 WeakPolarHBondContact CG2-OH 3.37Å; W39-Y72 AromaticContact CH2-CE2 3.8Å; W39-Y72 HydrophobicContact CH2-CE2 3.8Å; W39-Y72 AromaticContact CH2-CZ 3.94Å; W39-Y72 HydrophobicContact CZ2-CE2 4.4Å; W43-Y72 HydrophobicContact CH2-CD1 4.48Å; W43-Y72 HydrophobicContact CH2-CG 4.46Å; W43-Y72 AromaticContact CZ3-CD1 3.89Å; W43-Y72 HydrophobicContact CZ3-CD1 3.89Å; W43-Y72 HydrophobicContact CZ3-CD2 4.18Å; W43-Y72 AromaticContact CZ3-CE1 3.88Å; W43-Y72 HydrophobicContact CZ3-CE1 3.88Å; W43-Y72 HydrophobicContact CZ3-CE2 4.17Å; W43-Y72 HydrophobicContact CZ3-CG 4.05Å; F50-Y72 HydrophobicContact CE2-CD1 4.27Å; F50-Y72 HydrophobicContact CE2-CE1 4.08Å; F50-Y72 HydrophobicContact CZ-CE1 4.17Å; L60-Y72 HydrophobicContact CD1-CD1 4.03Å; L60-Y72 HydrophobicContact CD1-CE1 4.27Å; V63-Y72 HydrophobicContact CG1-CD1 4.3Å; V63-Y72 HydrophobicContact CG1-CD2 3.75Å; V63-Y72 HydrophobicContact CG1-CE1 4.39Å; V63-Y72 HydrophobicContact CG1-CE2 3.86Å; V63-Y72 HydrophobicContact CG1-CG 3.98Å; V63-Y72 HydrophobicContact CG2-CE1 4.46Å; Q67-Y72 HydrophobicContact CB-CD2 4.39Å; Q67-Y72 HydrophobicContact CB-CE2 4.11Å; Q67-Y72 PolarHBondContact O-N 3.26Å; F68-Y72 PolarHBondContact O-N 2.97Å; F68-Y72 VanDerWaalsContact O-N 3.1Å; Y72-K74 VanDerWaalsContact C-N 3.28Å; Y72-K74 PolarHBondContact O-N 2.77Å; Y72-L75 PolarHBondContact O-N 3.25Å; Y72-F76 WeakPolarHBondContact O-CB 3.14Å; Y72-F76 VanDerWaalsContact O-CD2 3.27Å; Y72-F76 WeakPolarHBondContact O-CD2 3.34Å; Y72-F76 PolarHBondContact O-N 2.83Å
73E98.4Very high98Very high68 Ų6852.1 Ų52.132%0.31828%0.276SS..Iπ-helixtrans-59.1-42-178.4-169.2-174.1-133.100111.2F68 F76 N77F68-E73 HydrophobicContact CD1-CB 4.45Å; F68-E73 HydrophobicContact CE1-CB 4.01Å; F68-E73 HydrophobicContact CE1-CG 4.37Å; F68-E73 HydrophobicContact CZ-CB 4.07Å; F68-E73 HydrophobicContact CZ-CG 4.43Å; F68-E73 PolarHBondContact O-N 2.88Å; E73-F76 PolarHBondContact O-N 3.22Å; E73-N77 WeakPolarHBondContact CG-ND2 3.33Å; E73-N77 VanDerWaalsContact O-CB 3.24Å; E73-N77 WeakPolarHBondContact O-CB 3.29Å; E73-N77 PolarHBondContact O-N 2.84Å; E73-N77 PolarHBondContact O-ND2 3.09Å
74K98.5Very high98Very high121 Ų12152.6 Ų52.653%0.52628%0.279SS..Hα-helixtrans-57.6-51175.5-175.7179.2179.3-178.30112.6D69 S70 Y72 Q78D69-K74 PolarHBondContact O-N 3.29Å; S70-K74 WeakPolarHBondContact O-CD 3.16Å; Y72-K74 VanDerWaalsContact C-N 3.28Å; Y72-K74 PolarHBondContact O-N 2.77Å; K74-Q78 VanDerWaalsContact O-CG 3.28Å; K74-Q78 WeakPolarHBondContact O-CG 3.2Å; K74-Q78 PolarHBondContact O-N 3.44Å; K74-Q78 VanDerWaalsContact O-N 3.16Å
75L98.6Very high98Very high22 Ų2254.5 Ų54.512%0.11529%0.287CS..Hα-helixtrans-63.1-51178.9175.364.9000110.9W43 F50 Y71 Y72 N77 Q78 L79W43-L75 HydrophobicContact CH2-CB 4.09Å; W43-L75 HydrophobicContact CH2-CD2 3.76Å; W43-L75 HydrophobicContact CZ2-CB 4.06Å; W43-L75 HydrophobicContact CZ2-CD2 3.9Å; F50-L75 HydrophobicContact CD2-CD2 3.96Å; Y71-L75 WeakPolarHBondContact O-CB 2.94Å; Y71-L75 PolarHBondContact O-N 2.94Å; Y72-L75 PolarHBondContact O-N 3.25Å; L75-N77 VanDerWaalsContact C-N 3.32Å; L75-N77 PolarHBondContact O-N 3.2Å; L75-Q78 WeakPolarHBondContact O-CB 3.46Å; L75-Q78 PolarHBondContact O-N 2.86Å; L75-L79 HydrophobicContact CD1-CD1 3.94Å; L75-L79 HydrophobicContact CD1-CG 4.17Å; L75-L79 HydrophobicContact CG-CD1 3.93Å; L75-L79 HydrophobicContact CG-CG 4.46Å; L75-L79 WeakPolarHBondContact O-CG 3.35Å; L75-L79 PolarHBondContact O-N 3.17Å
76F98.8Very high98.1Very high0 Ų054.9 Ų54.90%029%0.285CS..Hα-helixtrans-62.9-38-177-84.6-71.8000112F50 F58 L60 Y72 E73 Q78 L79 G80 Y81 F99F50-F76 HydrophobicContact CB-CZ 4.25Å; F50-F76 HydrophobicContact CD1-CZ 4.27Å; F50-F76 HydrophobicContact CD2-CE2 4.18Å; F50-F76 HydrophobicContact CD2-CZ 4.19Å; F50-F76 HydrophobicContact CE2-CE2 4.42Å; F50-F76 HydrophobicContact CG-CE2 4.44Å; F50-F76 AromaticContact CG-CZ 3.99Å; F50-F76 HydrophobicContact CG-CZ 3.99Å; F58-F76 HydrophobicContact CB-CE1 4.28Å; F58-F76 HydrophobicContact CB-CZ 4.21Å; F58-F76 AromaticContact CD2-CE1 3.48Å; F58-F76 HydrophobicContact CD2-CE1 3.48Å; F58-F76 VanDerWaalsContact CD2-CE1 3.48Å; F58-F76 AromaticContact CD2-CZ 3.98Å; F58-F76 HydrophobicContact CD2-CZ 3.98Å; F58-F76 AromaticContact CE2-CE1 3.91Å; F58-F76 HydrophobicContact CE2-CE1 3.91Å; F58-F76 HydrophobicContact CE2-CZ 4.45Å; F58-F76 AromaticContact CG-CE1 3.96Å; F58-F76 HydrophobicContact CG-CE1 3.96Å; F58-F76 HydrophobicContact CG-CZ 4Å; L60-F76 HydrophobicContact CD1-CE2 3.94Å; L60-F76 HydrophobicContact CD1-CZ 4.25Å; Y72-F76 WeakPolarHBondContact O-CB 3.14Å; Y72-F76 VanDerWaalsContact O-CD2 3.27Å; Y72-F76 WeakPolarHBondContact O-CD2 3.34Å; Y72-F76 PolarHBondContact O-N 2.83Å; E73-F76 PolarHBondContact O-N 3.22Å; F76-Q78 PolarHBondContact O-N 2.88Å; F76-L79 CarbonylContact O-C 3.57Å; F76-L79 PolarHBondContact O-N 3.06Å; F76-G80 PolarHBondContact O-N 3.39Å; F76-Y81 AromaticContact CD1-CD1 3.93Å; F76-Y81 HydrophobicContact CD1-CD1 3.93Å; F76-Y81 AromaticContact CD1-CD2 3.89Å; F76-Y81 HydrophobicContact CD1-CD2 3.89Å; F76-Y81 HydrophobicContact CD1-CE1 4.37Å; F76-Y81 HydrophobicContact CD1-CE2 4.34Å; F76-Y81 AromaticContact CD1-CG 3.69Å; F76-Y81 HydrophobicContact CD1-CG 3.69Å; F76-Y81 HydrophobicContact CE1-CD1 4.37Å; F76-Y81 HydrophobicContact CE1-CE1 4.42Å; F76-Y81 WeakPolarHBondContact O-CA 3.48Å; F76-Y81 WeakPolarHBondContact O-CB 3.4Å; F76-Y81 WeakPolarHBondContact O-CD2 3.5Å; F76-Y81 PolarHBondContact O-N 3.4Å; F76-F99 HydrophobicContact CB-CD1 3.44Å; F76-F99 VanDerWaalsContact CB-CD1 3.44Å; F76-F99 HydrophobicContact CB-CE1 3.6Å; F76-F99 HydrophobicContact CB-CG 4.02Å; F76-F99 HydrophobicContact CB-CZ 4.29Å; F76-F99 HydrophobicContact CD1-CB 3.79Å; F76-F99 HydrophobicContact CD1-CD1 4.11Å; F76-F99 HydrophobicContact CD1-CD2 4.23Å; F76-F99 AromaticContact CD1-CG 3.8Å; F76-F99 HydrophobicContact CD1-CG 3.8Å; F76-F99 AromaticContact CD2-CD1 3.81Å; F76-F99 HydrophobicContact CD2-CD1 3.81Å; F76-F99 AromaticContact CD2-CD2 3.55Å; F76-F99 HydrophobicContact CD2-CD2 3.55Å; F76-F99 AromaticContact CD2-CE1 3.72Å; F76-F99 HydrophobicContact CD2-CE1 3.72Å; F76-F99 AromaticContact CD2-CE2 3.44Å; F76-F99 HydrophobicContact CD2-CE2 3.44Å; F76-F99 VanDerWaalsContact CD2-CE2 3.44Å; F76-F99 AromaticContact CD2-CG 3.72Å; F76-F99 HydrophobicContact CD2-CG 3.72Å; F76-F99 AromaticContact CD2-CZ 3.52Å; F76-F99 HydrophobicContact CD2-CZ 3.52Å; F76-F99 HydrophobicContact CE1-CB 4.07Å; F76-F99 HydrophobicContact CE1-CD2 4.26Å; F76-F99 HydrophobicContact CE1-CG 4.19Å; F76-F99 AromaticContact CE2-CD2 3.59Å; F76-F99 HydrophobicContact CE2-CD2 3.59Å; F76-F99 AromaticContact CE2-CE2 3.62Å; F76-F99 HydrophobicContact CE2-CE2 3.62Å; F76-F99 HydrophobicContact CE2-CG 4.13Å; F76-F99 HydrophobicContact CE2-CZ 4.17Å; F76-F99 HydrophobicContact CG-CB 4.07Å; F76-F99 AromaticContact CG-CD1 3.51Å; F76-F99 HydrophobicContact CG-CD1 3.51Å; F76-F99 AromaticContact CG-CD2 3.9Å; F76-F99 HydrophobicContact CG-CD2 3.9Å; F76-F99 AromaticContact CG-CE1 3.8Å; F76-F99 HydrophobicContact CG-CE1 3.8Å; F76-F99 HydrophobicContact CG-CE2 4.15Å; F76-F99 AromaticContact CG-CG 3.55Å; F76-F99 HydrophobicContact CG-CG 3.55Å; F76-F99 HydrophobicContact CG-CZ 4.09Å; F76-F99 AromaticContact CZ-CD2 3.96Å; F76-F99 HydrophobicContact CZ-CD2 3.96Å; F76-F99 HydrophobicContact CZ-CE2 4.42Å; F76-F99 HydrophobicContact CZ-CG 4.34Å
77N98.5Very high98.2Very high73 Ų7354.4 Ų54.439%0.3927%0.274SS..Hα-helixtrans-61.4-42.9171.6-83.1-38.8000112.4E73 L75 L79 G80 Y81E73-N77 WeakPolarHBondContact CG-ND2 3.33Å; E73-N77 VanDerWaalsContact O-CB 3.24Å; E73-N77 WeakPolarHBondContact O-CB 3.29Å; E73-N77 PolarHBondContact O-N 2.84Å; E73-N77 PolarHBondContact O-ND2 3.09Å; L75-N77 VanDerWaalsContact C-N 3.32Å; L75-N77 PolarHBondContact O-N 3.2Å; N77-L79 VanDerWaalsContact C-N 3.25Å; N77-L79 PolarHBondContact O-N 3.22Å; N77-G80 PolarHBondContact O-N 3.25Å; N77-G80 VanDerWaalsContact O-N 3.09Å; N77-Y81 PolarHBondContact OD1-O 3.02Å
78Q98.4Very high98.2Very high136 Ų13654.7 Ų54.764%0.63628%0.275SS*.Hα-helixtrans-62.8-33.8176.5-71.7171.2-3.200112.2K74 L75 F76 G80K74-Q78 VanDerWaalsContact O-CG 3.28Å; K74-Q78 WeakPolarHBondContact O-CG 3.2Å; K74-Q78 PolarHBondContact O-N 3.44Å; K74-Q78 VanDerWaalsContact O-N 3.16Å; L75-Q78 WeakPolarHBondContact O-CB 3.46Å; L75-Q78 PolarHBondContact O-N 2.86Å; F76-Q78 PolarHBondContact O-N 2.88Å; Q78-G80 PolarHBondContact O-N 2.94Å
79L98.6Very high97.9Very high68 Ų6854.7 Ų54.736%0.35628%0.277SS..THydrogen-bonded Turntrans-82.33.6176.5-60.5176.6000113.4V51 L75 F76 N77 Y81V51-L79 HydrophobicContact CG2-CD1 3.9Å; V51-L79 HydrophobicContact CG2-CD2 4.14Å; L75-L79 HydrophobicContact CD1-CD1 3.94Å; L75-L79 HydrophobicContact CD1-CG 4.17Å; L75-L79 HydrophobicContact CG-CD1 3.93Å; L75-L79 HydrophobicContact CG-CG 4.46Å; L75-L79 WeakPolarHBondContact O-CG 3.35Å; L75-L79 PolarHBondContact O-N 3.17Å; F76-L79 CarbonylContact O-C 3.57Å; F76-L79 PolarHBondContact O-N 3.06Å; N77-L79 VanDerWaalsContact C-N 3.25Å; N77-L79 PolarHBondContact O-N 3.22Å; L79-Y81 HydrophobicContact CB-CD2 3.66Å; L79-Y81 HydrophobicContact CB-CE2 3.66Å; L79-Y81 WeakPolarHBondContact O-CD2 3.5Å; L79-Y81 WeakPolarHBondContact O-CE2 3.39Å
80G98.6Very high97.6Very high39 Ų3955.1 Ų55.140%0.40227%0.273SS..THydrogen-bonded Turntrans84.121.3176.200000115.1F76 N77 Q78 A102F76-G80 PolarHBondContact O-N 3.39Å; N77-G80 PolarHBondContact O-N 3.25Å; N77-G80 VanDerWaalsContact O-N 3.09Å; Q78-G80 PolarHBondContact O-N 2.94Å; G80-A102 WeakPolarHBondContact O-CB 3.28Å; G80-A102 PolarHBondContact O-N 2.8Å
81Y98.9Very high97Very high3 Ų360.2 Ų60.21%0.01230%0.295CS..EExtended strand (participates in β ladder)trans-94.9159176-63.7-112.5000111.4D54 A55 F58 F76 N77 L79 F99 W100 K101D54-Y81 PolarHBondContact OD1-OH 2.79Å; A55-Y81 WeakPolarHBondContact O-CE1 3.19Å; A55-Y81 PolarHBondContact O-OH 2.85Å; F58-Y81 AromaticContact CD2-CE1 3.91Å; F58-Y81 HydrophobicContact CD2-CE1 3.91Å; F58-Y81 HydrophobicContact CE2-CE1 4.15Å; F76-Y81 AromaticContact CD1-CD1 3.93Å; F76-Y81 HydrophobicContact CD1-CD1 3.93Å; F76-Y81 AromaticContact CD1-CD2 3.89Å; F76-Y81 HydrophobicContact CD1-CD2 3.89Å; F76-Y81 HydrophobicContact CD1-CE1 4.37Å; F76-Y81 HydrophobicContact CD1-CE2 4.34Å; F76-Y81 AromaticContact CD1-CG 3.69Å; F76-Y81 HydrophobicContact CD1-CG 3.69Å; F76-Y81 HydrophobicContact CE1-CD1 4.37Å; F76-Y81 HydrophobicContact CE1-CE1 4.42Å; F76-Y81 WeakPolarHBondContact O-CA 3.48Å; F76-Y81 WeakPolarHBondContact O-CB 3.4Å; F76-Y81 WeakPolarHBondContact O-CD2 3.5Å; F76-Y81 PolarHBondContact O-N 3.4Å; N77-Y81 PolarHBondContact OD1-O 3.02Å; L79-Y81 HydrophobicContact CB-CD2 3.66Å; L79-Y81 HydrophobicContact CB-CE2 3.66Å; L79-Y81 WeakPolarHBondContact O-CD2 3.5Å; L79-Y81 WeakPolarHBondContact O-CE2 3.39Å; Y81-F99 HydrophobicContact CD1-CB 4.12Å; Y81-W100 CarbonylContact C-O 3.56Å; Y81-W100 WeakPolarHBondContact CA-O 3.43Å; Y81-W100 WeakPolarHBondContact CB-O 3.17Å; Y81-W100 VanDerWaalsContact CD1-C 3.41Å; Y81-K101 HydrophobicContact CD1-CG 3.93Å; Y81-K101 HydrophobicContact CD2-CG 4.36Å; Y81-K101 HydrophobicContact CE1-CB 4.49Å; Y81-K101 HydrophobicContact CE1-CG 3.47Å; Y81-K101 VanDerWaalsContact CE1-CG 3.47Å; Y81-K101 HydrophobicContact CE2-CG 3.95Å; Y81-K101 HydrophobicContact CG-CG 4.34Å; Y81-K101 VanDerWaalsContact CZ-CG 3.49Å; Y81-K101 WeakPolarHBondContact OH-CE 3.49Å
82K98.7Very high96.6Very high114 Ų11460.7 Ų60.750%0.49630%0.299SS..EExtended strand (participates in β ladder)trans-109.2158.8156.6-63.9-59.7-179-172.90108.7F99 W100 A102K82-F99 CarbonylContact O-C 3.5Å; K82-F99 WeakPolarHBondContact O-CA 3.12Å; K82-W100 HydrophobicContact CB-CD2 4.46Å; K82-W100 HydrophobicContact CB-CZ2 3.78Å; K82-W100 PolarHBondContact N-O 2.87Å; K82-W100 PolarHBondContact O-N 2.82Å; K82-A102 HydrophobicContact CG-CB 4.11Å
83G98.4Very high96.4Very high27 Ų2761.5 Ų61.528%0.27831%0.306SS..EExtended strand (participates in β ladder)trans-140.3157-177.400000113.1T98 F99G83-T98 CarbonylContact C-O 3.56Å; G83-T98 VanDerWaalsContact CA-O 3.27Å; G83-T98 WeakPolarHBondContact CA-O 3.05Å; G83-F99 VanDerWaalsContact CA-CD1 3.46Å
84A98.6Very high96.4Very high9 Ų958.4 Ų58.47%0.07429%0.292CS..EExtended strand (participates in β ladder)trans-128.3145.1164.600000108.4A97 T98 W100 I110 L129 V131A84-A97 CarbonylContact O-C 3.59Å; A84-A97 VanDerWaalsContact O-CA 3.25Å; A84-A97 WeakPolarHBondContact O-CA 3.21Å; A84-T98 PolarHBondContact N-O 2.94Å; A84-T98 PolarHBondContact O-N 3.31Å; A84-W100 HydrophobicContact CB-CH2 4.09Å; A84-W100 HydrophobicContact CB-CZ3 4.07Å; A84-I110 HydrophobicContact CB-CD1 3.62Å; A84-I110 HydrophobicContact CB-CG1 4.41Å; A84-L129 HydrophobicContact CB-CD1 4.46Å; A84-L129 HydrophobicContact CB-CD2 4.25Å; A84-L129 WeakPolarHBondContact O-CD2 3.15Å; A84-V131 HydrophobicContact CB-CG1 4.31Å
85Y98.7Very high96.4Very high45 Ų4552.7 Ų52.718%0.17627%0.267CS..EExtended strand (participates in β ladder)trans-136.6137.1178.3170.4-108.4000110.7V63 A65 F68 R87 G95 C96 A97V63-Y85 HydrophobicContact CB-CD2 4.41Å; V63-Y85 HydrophobicContact CB-CE2 4.01Å; V63-Y85 HydrophobicContact CG1-CD2 4.4Å; V63-Y85 HydrophobicContact CG1-CE2 4.17Å; V63-Y85 PolarHBondContact O-OH 2.96Å; A65-Y85 WeakPolarHBondContact CA-OH 3.24Å; A65-Y85 HydrophobicContact CB-CE1 4.33Å; A65-Y85 WeakPolarHBondContact CB-OH 3.46Å; F68-Y85 HydrophobicContact CB-CD1 4.42Å; F68-Y85 HydrophobicContact CB-CE1 4.48Å; F68-Y85 HydrophobicContact CD1-CD1 4.05Å; F68-Y85 HydrophobicContact CD1-CG 4.11Å; F68-Y85 HydrophobicContact CD2-CD1 4.39Å; F68-Y85 AromaticContact CD2-CD2 3.92Å; F68-Y85 HydrophobicContact CD2-CD2 3.92Å; F68-Y85 AromaticContact CD2-CG 3.78Å; F68-Y85 HydrophobicContact CD2-CG 3.78Å; F68-Y85 HydrophobicContact CE1-CG 4.29Å; F68-Y85 VanDerWaalsContact CE2-CB 3.43Å; F68-Y85 HydrophobicContact CE2-CD2 4.26Å; F68-Y85 AromaticContact CE2-CG 3.96Å; F68-Y85 HydrophobicContact CE2-CG 3.96Å; F68-Y85 HydrophobicContact CG-CD1 4Å; F68-Y85 HydrophobicContact CG-CD2 4.3Å; F68-Y85 AromaticContact CG-CG 3.87Å; F68-Y85 HydrophobicContact CG-CG 3.87Å; F68-Y85 HydrophobicContact CZ-CG 4.22Å; Y85-R87 HydrophobicContact CE1-CB 3.85Å; Y85-G95 PolarHBondContact OH-N 3.49Å; Y85-C96 WeakPolarHBondContact CA-O 3.31Å; Y85-C96 VanDerWaalsContact CD2-O 3.31Å; Y85-C96 WeakPolarHBondContact CD2-O 3.13Å; Y85-A97 HydrophobicContact CD2-CB 4.09Å
86K98.2Very high96.4Very high29 Ų2951.6 Ų51.613%0.12626%0.261CS..EExtended strand (participates in β ladder)trans-127.2112.3170.4177.353.6169.3-160.80109.4G95 C96 E112 E114 I127 L129K86-G95 CarbonylContact O-C 3.48Å; K86-G95 WeakPolarHBondContact O-CA 3.25Å; K86-C96 PolarHBondContact N-O 3.46Å; K86-C96 PolarHBondContact O-N 2.88Å; K86-E112 HydrophobicContact CB-CG 4.24Å; K86-E112 HydrophobicContact CD-CB 4.19Å; K86-E112 HydrophobicContact CD-CG 4.06Å; K86-E112 VanDerWaalsContact CD-OE2 3.3Å; K86-E112 WeakPolarHBondContact CD-OE2 3.24Å; K86-E112 WeakPolarHBondContact CE-OE2 3.24Å; K86-E112 HydrophobicContact CG-CB 4.22Å; K86-E112 HydrophobicContact CG-CG 4.17Å; K86-E112 IonicContact NZ-OE2 2.72Å; K86-E112 PolarHBondContact NZ-OE2 3.04Å; K86-E114 VanDerWaalsContact CE-OE1 3.28Å; K86-E114 WeakPolarHBondContact CE-OE1 3.23Å; K86-E114 IonicContact NZ-OE1 2.7Å; K86-E114 PolarHBondContact NZ-OE1 2.85Å; K86-I127 HydrophobicContact CB-CD1 4.06Å; K86-I127 HydrophobicContact CG-CB 4.15Å; K86-I127 HydrophobicContact CG-CD1 3.96Å; K86-I127 HydrophobicContact CG-CG1 4Å; K86-I127 HydrophobicContact CG-CG2 4.3Å; K86-I127 WeakPolarHBondContact O-CD1 3.18Å; K86-L129 HydrophobicContact CB-CD1 4.23Å
87R97.8Very high96.4Very high104 Ų10451.6 Ų51.639%0.39226%0.261SS..EExtended strand (participates in β ladder)trans-62.5142.7167.6-165.6-178.9176.31670.5110.3A65 Y85 K92A65-R87 HydrophobicContact CB-CG 4.09Å; Y85-R87 HydrophobicContact CE1-CB 3.85Å; R87-K92 PolarHBondContact NE-O 2.98Å; R87-K92 PolarHBondContact NH2-O 2.92Å
88K97Very high96.4Very high20 Ų2048.1 Ų48.19%0.08724%0.243CC..PPolyproline II helixtrans-55.6153.2165.3-76.1177.9-178.5161.90110.2K92 D94 D125 I127 H157K88-K92 HydrophobicContact CB-CB 3.61Å; K88-K92 HydrophobicContact CB-CG 4.09Å; K88-K92 HydrophobicContact CD-CB 4.41Å; K88-D94 VanDerWaalsContact CB-O 3.31Å; K88-D94 WeakPolarHBondContact CB-O 3.28Å; K88-D94 VanDerWaalsContact CE-OD2 3.29Å; K88-D94 WeakPolarHBondContact CE-OD2 3.44Å; K88-D94 PolarHBondContact N-O 3.2Å; K88-D94 IonicContact NZ-OD1 2.94Å; K88-D94 IonicContact NZ-OD2 3.21Å; K88-D94 PolarHBondContact NZ-OD2 3.39Å; K88-D125 WeakPolarHBondContact CA-O 3.37Å; K88-D125 WeakPolarHBondContact CB-O 3.28Å; K88-D125 WeakPolarHBondContact CG-O 3.45Å; K88-I127 HydrophobicContact CG-CG1 4.14Å; K88-H157 PolarHBondContact NZ-CE1 2.99Å; K88-H157 PolarHBondContact NZ-ND1 3.33Å
89T92.9Very high96.4Very high14 Ų1441.7 Ų41.79%0.08621%0.213CC..SBendtrans-70173.4-176.660.10000112.1E114 F116 D125 I127T89-E114 HydrophobicContact CG2-CB 3.9Å; T89-E114 VanDerWaalsContact CG2-CD 3.46Å; T89-E114 HydrophobicContact CG2-CG 3.61Å; T89-F116 HydrophobicContact CG2-CB 4.48Å; T89-D125 PolarHBondContact N-O 2.9Å; T89-D125 WeakPolarHBondContact OG1-CA 3.47Å; T89-D125 WeakPolarHBondContact OG1-CB 3.32Å; T89-D125 PolarHBondContact OG1-O 3.22Å; T89-D125 PolarHBondContact OG1-OD1 3.31Å; T89-I127 HydrophobicContact CG2-CG2 4.28Å
90K88.3Confident96.4Very high117 Ų11738.8 Ų38.851%0.50920%0.197SC..THydrogen-bonded Turntrans56.5-136.2-175.4-56.4-173.9-168.7119.60111.4F116 V123 D125K90-F116 VanDerWaalsContact NZ-CE2 3.34Å; K90-V123 PolarHBondContact NZ-O 3.49Å; K90-D125 WeakPolarHBondContact CD-OD1 3.39Å; K90-D125 WeakPolarHBondContact CE-OD1 3.28Å; K90-D125 WeakPolarHBondContact CG-OD1 3.38Å; K90-D125 IonicContact NZ-OD1 3.3Å; K90-D125 PolarHBondContact NZ-OD1 3.06Å; K90-D125 IonicContact NZ-OD2 2.65Å
91L85.1Confident96.4Very high163 Ų16338.1 Ų38.185%0.85318%0.183SC*.THydrogen-bonded Turntrans-103.619.9-174.5-61.9175.5000112.6
92K90Very high96.4Very high100 Ų10040 Ų4044%0.43520%0.199SC..  trans-62.5137.6176.2-67.6-61-174.5176.40110.1R87 K88 D94 D125R87-K92 PolarHBondContact NE-O 2.98Å; R87-K92 PolarHBondContact NH2-O 2.92Å; K88-K92 HydrophobicContact CB-CB 3.61Å; K88-K92 HydrophobicContact CB-CG 4.09Å; K88-K92 HydrophobicContact CD-CB 4.41Å; K92-D94 VanDerWaalsContact C-N 3.27Å; K92-D94 PolarHBondContact O-N 3.14Å; K92-D125 VanDerWaalsContact CE-OD2 3.28Å; K92-D125 WeakPolarHBondContact CE-OD2 3.44Å; K92-D125 HydrophobicContact CG-CB 3.68Å
93A94Very high96.3Very high19 Ų1940.3 Ų40.316%0.15721%0.206CC..SBendtrans-74.5-20.4-173.400000112.7D20 Q64 A65D20-A93 HydrophobicContact CB-CB 3.84Å; Q64-A93 HydrophobicContact CG-CB 4.41Å; A65-A93 VanDerWaalsContact CB-O 3.29Å; A65-A93 WeakPolarHBondContact CB-O 3.45Å; A65-A93 PolarHBondContact N-O 3.15Å
94D97.5Very high96.2Very high4 Ų442.1 Ų42.12%0.02121%0.206CC..EExtended strand (participates in β ladder)trans-118.4173.6-166.769.2-52.6000114.3C18 V63 K88 K92C18-D94 HydrophobicContact CB-CB 3.7Å; V63-D94 CarbonylContact O-C 3.52Å; V63-D94 VanDerWaalsContact O-CA 3.26Å; V63-D94 WeakPolarHBondContact O-CA 3.2Å; K88-D94 VanDerWaalsContact CB-O 3.31Å; K88-D94 WeakPolarHBondContact CB-O 3.28Å; K88-D94 VanDerWaalsContact CE-OD2 3.29Å; K88-D94 WeakPolarHBondContact CE-OD2 3.44Å; K88-D94 PolarHBondContact N-O 3.2Å; K88-D94 IonicContact NZ-OD1 2.94Å; K88-D94 IonicContact NZ-OD2 3.21Å; K88-D94 PolarHBondContact NZ-OD2 3.39Å; K92-D94 VanDerWaalsContact C-N 3.27Å; K92-D94 PolarHBondContact O-N 3.14Å
95G98.2Very high96.1Very high0 Ų041.9 Ų41.90%020%0.204CC..EExtended strand (participates in β ladder)trans-161.9-168-179.700000113.3E62 V63 Y85 K86E62-G95 PolarHBondContact N-O 3.09Å; V63-G95 PolarHBondContact N-O 2.82Å; V63-G95 PolarHBondContact O-N 3.43Å; Y85-G95 PolarHBondContact OH-N 3.49Å; K86-G95 CarbonylContact O-C 3.48Å; K86-G95 WeakPolarHBondContact O-CA 3.25Å
96C98.8Very high96Very high0 Ų044.4 Ų44.40%022%0.217CC..EExtended strand (participates in β ladder)trans-111.7137.1172.1-62.20000109.9L60 Y85 K86 I127 L129L60-C96 CarbonylContact O-C 3.57Å; L60-C96 VanDerWaalsContact O-CA 3.27Å; L60-C96 WeakPolarHBondContact O-CA 3.49Å; Y85-C96 WeakPolarHBondContact CA-O 3.31Å; Y85-C96 VanDerWaalsContact CD2-O 3.31Å; Y85-C96 WeakPolarHBondContact CD2-O 3.13Å; K86-C96 PolarHBondContact N-O 3.46Å; K86-C96 PolarHBondContact O-N 2.88Å; C96-I127 HydrophobicContact CB-CD1 3.58Å; C96-I127 VanDerWaalsContact SG-CD1 3.58Å; C96-L129 HydrophobicContact CB-CB 4.39Å; C96-L129 WeakPolarHBondContact O-CD2 3.4Å
97A98.9Very high96Very high0 Ų046.4 Ų46.40%023%0.229CC..EExtended strand (participates in β ladder)trans-115.8145.4171.700000110.4L60 V63 F68 A84 Y85 F99 N155L60-A97 HydrophobicContact CB-CB 4.4Å; L60-A97 PolarHBondContact N-O 3.5Å; L60-A97 PolarHBondContact O-N 2.84Å; V63-A97 HydrophobicContact CB-CB 4.48Å; V63-A97 HydrophobicContact CG2-CB 3.95Å; F68-A97 HydrophobicContact CD2-CB 4.44Å; F68-A97 HydrophobicContact CE2-CB 3.97Å; A84-A97 CarbonylContact O-C 3.59Å; A84-A97 VanDerWaalsContact O-CA 3.25Å; A84-A97 WeakPolarHBondContact O-CA 3.21Å; Y85-A97 HydrophobicContact CD2-CB 4.09Å; A97-F99 HydrophobicContact CB-CD2 4.23Å; A97-F99 HydrophobicContact CB-CE2 3.61Å; A97-F99 HydrophobicContact CB-CZ 4.21Å; A97-N155 PolarHBondContact O-ND2 3.04Å
98T98.9Very high96Very high0 Ų044.7 Ų44.70%023%0.23CC..EExtended strand (participates in β ladder)trans-125.9121.6167.6-560000108.7I57 F58 G83 A84 W100 V131I57-T98 HydrophobicContact CG2-CG2 4.12Å; F58-T98 CarbonylContact O-C 3.57Å; F58-T98 VanDerWaalsContact O-CA 3.24Å; F58-T98 WeakPolarHBondContact O-CA 3.44Å; G83-T98 CarbonylContact C-O 3.56Å; G83-T98 VanDerWaalsContact CA-O 3.27Å; G83-T98 WeakPolarHBondContact CA-O 3.05Å; A84-T98 PolarHBondContact N-O 2.94Å; A84-T98 PolarHBondContact O-N 3.31Å; T98-W100 HydrophobicContact CG2-CE3 4.31Å; T98-W100 VanDerWaalsContact O-CZ3 3.24Å; T98-W100 WeakPolarHBondContact O-CZ3 3.44Å; T98-V131 HydrophobicContact CG2-CG2 3.76Å
99F98.9Very high96Very high1 Ų148.6 Ų48.60%0.00425%0.247CC..EExtended strand (participates in β ladder)trans-111.8145.1176.2-62.6-83.4000110.3I57 F58 L60 F68 F76 Y81 K82 G83 A97I57-F99 CarbonylContact C-O 3.51Å; I57-F99 VanDerWaalsContact CA-O 3.22Å; I57-F99 WeakPolarHBondContact CA-O 3.4Å; I57-F99 WeakPolarHBondContact CG2-O 3.34Å; F58-F99 HydrophobicContact CB-CB 4.34Å; F58-F99 PolarHBondContact N-O 2.78Å; F58-F99 PolarHBondContact O-N 3.16Å; L60-F99 HydrophobicContact CD1-CD2 4.09Å; L60-F99 HydrophobicContact CD1-CE2 3.9Å; F68-F99 HydrophobicContact CD2-CZ 4.35Å; F68-F99 HydrophobicContact CE2-CE1 4.12Å; F68-F99 HydrophobicContact CE2-CE2 4.27Å; F68-F99 AromaticContact CE2-CZ 3.47Å; F68-F99 HydrophobicContact CE2-CZ 3.47Å; F68-F99 VanDerWaalsContact CE2-CZ 3.47Å; F68-F99 HydrophobicContact CZ-CE1 4.32Å; F68-F99 HydrophobicContact CZ-CZ 4.11Å; F76-F99 HydrophobicContact CB-CD1 3.44Å; F76-F99 VanDerWaalsContact CB-CD1 3.44Å; F76-F99 HydrophobicContact CB-CE1 3.6Å; F76-F99 HydrophobicContact CB-CG 4.02Å; F76-F99 HydrophobicContact CB-CZ 4.29Å; F76-F99 HydrophobicContact CD1-CB 3.79Å; F76-F99 HydrophobicContact CD1-CD1 4.11Å; F76-F99 HydrophobicContact CD1-CD2 4.23Å; F76-F99 AromaticContact CD1-CG 3.8Å; F76-F99 HydrophobicContact CD1-CG 3.8Å; F76-F99 AromaticContact CD2-CD1 3.81Å; F76-F99 HydrophobicContact CD2-CD1 3.81Å; F76-F99 AromaticContact CD2-CD2 3.55Å; F76-F99 HydrophobicContact CD2-CD2 3.55Å; F76-F99 AromaticContact CD2-CE1 3.72Å; F76-F99 HydrophobicContact CD2-CE1 3.72Å; F76-F99 AromaticContact CD2-CE2 3.44Å; F76-F99 HydrophobicContact CD2-CE2 3.44Å; F76-F99 VanDerWaalsContact CD2-CE2 3.44Å; F76-F99 AromaticContact CD2-CG 3.72Å; F76-F99 HydrophobicContact CD2-CG 3.72Å; F76-F99 AromaticContact CD2-CZ 3.52Å; F76-F99 HydrophobicContact CD2-CZ 3.52Å; F76-F99 HydrophobicContact CE1-CB 4.07Å; F76-F99 HydrophobicContact CE1-CD2 4.26Å; F76-F99 HydrophobicContact CE1-CG 4.19Å; F76-F99 AromaticContact CE2-CD2 3.59Å; F76-F99 HydrophobicContact CE2-CD2 3.59Å; F76-F99 AromaticContact CE2-CE2 3.62Å; F76-F99 HydrophobicContact CE2-CE2 3.62Å; F76-F99 HydrophobicContact CE2-CG 4.13Å; F76-F99 HydrophobicContact CE2-CZ 4.17Å; F76-F99 HydrophobicContact CG-CB 4.07Å; F76-F99 AromaticContact CG-CD1 3.51Å; F76-F99 HydrophobicContact CG-CD1 3.51Å; F76-F99 AromaticContact CG-CD2 3.9Å; F76-F99 HydrophobicContact CG-CD2 3.9Å; F76-F99 AromaticContact CG-CE1 3.8Å; F76-F99 HydrophobicContact CG-CE1 3.8Å; F76-F99 HydrophobicContact CG-CE2 4.15Å; F76-F99 AromaticContact CG-CG 3.55Å; F76-F99 HydrophobicContact CG-CG 3.55Å; F76-F99 HydrophobicContact CG-CZ 4.09Å; F76-F99 AromaticContact CZ-CD2 3.96Å; F76-F99 HydrophobicContact CZ-CD2 3.96Å; F76-F99 HydrophobicContact CZ-CE2 4.42Å; F76-F99 HydrophobicContact CZ-CG 4.34Å; Y81-F99 HydrophobicContact CD1-CB 4.12Å; K82-F99 CarbonylContact O-C 3.5Å; K82-F99 WeakPolarHBondContact O-CA 3.12Å; G83-F99 VanDerWaalsContact CA-CD1 3.46Å; A97-F99 HydrophobicContact CB-CD2 4.23Å; A97-F99 HydrophobicContact CB-CE2 3.61Å; A97-F99 HydrophobicContact CB-CZ 4.21Å
100W98.8Very high96.2Very high7 Ų751 Ų513%0.02726%0.258CS..EExtended strand (participates in β ladder)trans-141.7143.8176.757.888.6000111.3D56 I57 Y81 K82 A84 T98 A102 F105 L107 V131 L133D56-W100 CarbonylContact O-C 3.59Å; D56-W100 WeakPolarHBondContact O-CA 3.38Å; I57-W100 HydrophobicContact CG1-CB 4.09Å; Y81-W100 CarbonylContact C-O 3.56Å; Y81-W100 WeakPolarHBondContact CA-O 3.43Å; Y81-W100 WeakPolarHBondContact CB-O 3.17Å; Y81-W100 VanDerWaalsContact CD1-C 3.41Å; K82-W100 HydrophobicContact CB-CD2 4.46Å; K82-W100 HydrophobicContact CB-CZ2 3.78Å; K82-W100 PolarHBondContact N-O 2.87Å; K82-W100 PolarHBondContact O-N 2.82Å; A84-W100 HydrophobicContact CB-CH2 4.09Å; A84-W100 HydrophobicContact CB-CZ3 4.07Å; T98-W100 HydrophobicContact CG2-CE3 4.31Å; T98-W100 VanDerWaalsContact O-CZ3 3.24Å; T98-W100 WeakPolarHBondContact O-CZ3 3.44Å; W100-A102 PolarHBondContact O-N 3.28Å; W100-F105 HydrophobicContact CB-CB 4.19Å; W100-F105 HydrophobicContact CB-CD2 4.13Å; W100-F105 HydrophobicContact CB-CG 4.44Å; W100-F105 HydrophobicContact CG-CB 4.14Å; W100-L107 HydrophobicContact CH2-CD1 3.98Å; W100-L107 HydrophobicContact CH2-CD2 4.29Å; W100-L107 HydrophobicContact CZ2-CB 3.78Å; W100-L107 HydrophobicContact CZ2-CD1 4Å; W100-L107 HydrophobicContact CZ2-CD2 4.15Å; W100-L107 HydrophobicContact CZ2-CG 4.19Å; W100-V131 HydrophobicContact CZ3-CG1 4.19Å; W100-L133 HydrophobicContact CB-CD1 3.94Å; W100-L133 HydrophobicContact CD2-CD1 4.27Å; W100-L133 HydrophobicContact CD2-CD2 3.7Å; W100-L133 HydrophobicContact CE3-CD1 4.49Å; W100-L133 HydrophobicContact CE3-CD2 4.09Å; W100-L133 HydrophobicContact CG-CD1 4.04Å; W100-L133 HydrophobicContact CG-CD2 4.01Å; W100-L133 HydrophobicContact CZ2-CD2 4.33Å
101K98.6Very high96.7Very high24 Ų2448.5 Ų48.510%0.10425%0.246CC..EExtended strand (participates in β ladder)trans-64.3122.9176.8-73-170.3-173.6165.50110.9D54 D56 Y81 N103 K104 F105D54-K101 PolarHBondContact O-NZ 2.8Å; D54-K101 WeakPolarHBondContact OD1-CE 3.37Å; D54-K101 IonicContact OD1-NZ 3.53Å; D54-K101 PolarHBondContact OD1-NZ 3.04Å; D54-K101 IonicContact OD2-NZ 3.47Å; D54-K101 PolarHBondContact OD2-NZ 2.82Å; D56-K101 HydrophobicContact CB-CD 4.47Å; D56-K101 PolarHBondContact O-N 2.67Å; D56-K101 WeakPolarHBondContact OD1-CD 3.47Å; D56-K101 IonicContact OD1-NZ 3.4Å; D56-K101 PolarHBondContact OD1-NZ 2.82Å; Y81-K101 HydrophobicContact CD1-CG 3.93Å; Y81-K101 HydrophobicContact CD2-CG 4.36Å; Y81-K101 HydrophobicContact CE1-CB 4.49Å; Y81-K101 HydrophobicContact CE1-CG 3.47Å; Y81-K101 VanDerWaalsContact CE1-CG 3.47Å; Y81-K101 HydrophobicContact CE2-CG 3.95Å; Y81-K101 HydrophobicContact CG-CG 4.34Å; Y81-K101 VanDerWaalsContact CZ-CG 3.49Å; Y81-K101 WeakPolarHBondContact OH-CE 3.49Å; K101-N103 WeakPolarHBondContact CB-OD1 3.43Å; K101-N103 PolarHBondContact O-N 3.27Å; K101-K104 HydrophobicContact CB-CB 4.42Å; K101-K104 PolarHBondContact O-N 3.35Å; K101-F105 PolarHBondContact O-N 3.1Å
102A98.1Very high97.4Very high43 Ų4345.2 Ų45.236%0.35523%0.226SC..THydrogen-bonded Turntrans-66.6-21.1-174.400000113.6G80 K82 W100G80-A102 WeakPolarHBondContact O-CB 3.28Å; G80-A102 PolarHBondContact O-N 2.8Å; K82-A102 HydrophobicContact CG-CB 4.11Å; W100-A102 PolarHBondContact O-N 3.28Å
103N96.3Very high97.7Very high121 Ų12140.5 Ų40.565%0.64721%0.206SC*.THydrogen-bonded Turntrans-83.5-11.8175.868.7-18.6000113.7K101K101-N103 WeakPolarHBondContact CB-OD1 3.43Å; K101-N103 PolarHBondContact O-N 3.27Å
104K95.7Very high97.9Very high64 Ų6444.3 Ų44.328%0.27822%0.22SC..THydrogen-bonded Turntrans-112.5-24.9179.5-72.3-172.7176.4-172.20113.3D56 K101 L136D56-K104 HydrophobicContact CB-CD 3.99Å; D56-K104 WeakPolarHBondContact OD1-CD 3.32Å; D56-K104 VanDerWaalsContact OD1-CE 3.26Å; D56-K104 WeakPolarHBondContact OD1-CE 3.42Å; D56-K104 IonicContact OD1-NZ 2.72Å; D56-K104 PolarHBondContact OD1-NZ 3.16Å; D56-K104 IonicContact OD2-NZ 3.56Å; D56-K104 PolarHBondContact OD2-NZ 3.32Å; K101-K104 HydrophobicContact CB-CB 4.42Å; K101-K104 PolarHBondContact O-N 3.35Å; K104-L136 WeakPolarHBondContact O-CB 3.27Å; K104-L136 PolarHBondContact O-N 3.39Å
105F97.1Very high97.8Very high4 Ų444.2 Ų44.22%0.01822%0.22CC..EExtended strand (participates in β ladder)trans-138.3138.4-175.4-57.3-81.1000112.6F9 D56 I57 W100 K101 L133 K134 V135 I151F9-F105 HydrophobicContact CB-CE2 4.37Å; F9-F105 HydrophobicContact CB-CZ 3.84Å; F9-F105 HydrophobicContact CD1-CZ 4.31Å; F9-F105 AromaticContact CD2-CZ 3.75Å; F9-F105 HydrophobicContact CD2-CZ 3.75Å; F9-F105 HydrophobicContact CE2-CZ 4.4Å; F9-F105 AromaticContact CG-CZ 3.7Å; F9-F105 HydrophobicContact CG-CZ 3.7Å; D56-F105 HydrophobicContact CB-CE2 4.03Å; I57-F105 HydrophobicContact CD1-CD2 4.32Å; I57-F105 HydrophobicContact CD1-CE1 4.11Å; I57-F105 HydrophobicContact CD1-CE2 3.87Å; I57-F105 HydrophobicContact CD1-CZ 3.76Å; I57-F105 HydrophobicContact CG1-CD2 4.11Å; I57-F105 HydrophobicContact CG1-CE2 3.73Å; I57-F105 HydrophobicContact CG1-CZ 4.14Å; W100-F105 HydrophobicContact CB-CB 4.19Å; W100-F105 HydrophobicContact CB-CD2 4.13Å; W100-F105 HydrophobicContact CB-CG 4.44Å; W100-F105 HydrophobicContact CG-CB 4.14Å; K101-F105 PolarHBondContact O-N 3.1Å; F105-L133 HydrophobicContact CB-CB 4.23Å; F105-L133 HydrophobicContact CB-CD1 4.2Å; F105-L133 HydrophobicContact CD1-CB 4.05Å; F105-L133 HydrophobicContact CD1-CD1 4.28Å; F105-L133 HydrophobicContact CG-CB 4.47Å; F105-L133 HydrophobicContact CG-CD1 4.2Å; F105-K134 VanDerWaalsContact CA-O 3.32Å; F105-K134 WeakPolarHBondContact CA-O 3.44Å; F105-V135 HydrophobicContact CD1-CG2 4.31Å; F105-V135 HydrophobicContact CE1-CB 4.45Å; F105-V135 HydrophobicContact CE1-CG1 4.27Å; F105-V135 HydrophobicContact CE1-CG2 3.99Å; F105-I151 HydrophobicContact CE1-CG2 4.32Å
106E96.9Very high97.6Very high99 Ų9947 Ų4746%0.46323%0.232SC..EExtended strand (participates in β ladder)trans-110.9135.8169.8177.3-176.7-167.600109.3V108 L133 K134 L136E106-V108 PolarHBondContact O-N 2.92Å; E106-L133 CarbonylContact O-C 3.58Å; E106-L133 WeakPolarHBondContact O-CA 3.46Å; E106-K134 HydrophobicContact CB-CB 4.34Å; E106-K134 PolarHBondContact N-O 3.17Å; E106-K134 PolarHBondContact O-N 3.05Å; E106-K134 IonicContact OE2-NZ 3.47Å; E106-L136 HydrophobicContact CB-CD1 4.46Å; E106-L136 HydrophobicContact CB-CD2 3.9Å; E106-L136 HydrophobicContact CB-CG 4.43Å
107L98.2Very high97.3Very high70 Ų7048.7 Ų48.737%0.36624%0.24SC..EExtended strand (participates in β ladder)trans-73125.3179.117966.2000110.8W100 I110 V131 L133W100-L107 HydrophobicContact CH2-CD1 3.98Å; W100-L107 HydrophobicContact CH2-CD2 4.29Å; W100-L107 HydrophobicContact CZ2-CB 3.78Å; W100-L107 HydrophobicContact CZ2-CD1 4Å; W100-L107 HydrophobicContact CZ2-CD2 4.15Å; W100-L107 HydrophobicContact CZ2-CG 4.19Å; L107-I110 HydrophobicContact CD1-CD1 4.3Å; L107-I110 HydrophobicContact CD1-CG1 3.68Å; L107-I110 HydrophobicContact CD2-CD1 3.65Å; L107-I110 HydrophobicContact CD2-CG1 3.82Å; L107-I110 HydrophobicContact CG-CG1 4.27Å; L107-V131 HydrophobicContact CD1-CB 4.47Å; L107-L133 HydrophobicContact CD1-CD2 4Å
108V96.8Very high96.8Very high68 Ų6853.2 Ų53.241%0.41227%0.27SS..EExtended strand (participates in β ladder)trans-96.9-46.8172.9178.90000110.7E106 C132 K134 E150E106-V108 PolarHBondContact O-N 2.92Å; V108-C132 HydrophobicContact CB-CB 4.22Å; V108-C132 WeakPolarHBondContact CB-O 3.47Å; V108-C132 PolarHBondContact N-O 2.91Å; V108-K134 HydrophobicContact CG2-CB 3.74Å; V108-E150 HydrophobicContact CG2-CG 4.24Å
109K97.6Very high96.2Very high102 Ų10257.4 Ų57.444%0.44331%0.313SS..EExtended strand (participates in β ladder)trans-158.1145.5-175.2-174.5169.7-176.2172.90111.8V131 C132K109-V131 WeakPolarHBondContact O-CA 3.32Å; K109-C132 HydrophobicContact CB-CB 4.11Å; K109-C132 PolarHBondContact N-O 3.24Å; K109-C132 PolarHBondContact O-N 3.49Å
110I98.6Very high95.7Very high65 Ų6558.8 Ų58.833%0.33332%0.321SS..EExtended strand (participates in β ladder)trans-112.2142.4167.4-58174.6000108.4A84 L107 E112 L129 V130 V131A84-I110 HydrophobicContact CB-CD1 3.62Å; A84-I110 HydrophobicContact CB-CG1 4.41Å; L107-I110 HydrophobicContact CD1-CD1 4.3Å; L107-I110 HydrophobicContact CD1-CG1 3.68Å; L107-I110 HydrophobicContact CD2-CD1 3.65Å; L107-I110 HydrophobicContact CD2-CG1 3.82Å; L107-I110 HydrophobicContact CG-CG1 4.27Å; I110-E112 HydrophobicContact CG2-CG 4.42Å; I110-L129 HydrophobicContact CG2-CD1 3.8Å; I110-V130 CarbonylContact C-O 3.53Å; I110-V130 WeakPolarHBondContact CA-O 3.01Å; I110-V131 HydrophobicContact CG1-CG1 4.3Å
111R98.6Very high94.8Very high64 Ų6462.4 Ų62.424%0.24235%0.348CS..EExtended strand (participates in β ladder)trans-130.7114.6166.617271.169.2144.312.2108.6V113 V130 H178 V182R111-V113 HydrophobicContact CG-CG2 3.94Å; R111-V130 HydrophobicContact CB-CB 4.15Å; R111-V130 PolarHBondContact N-O 3.36Å; R111-V130 PolarHBondContact O-N 2.88Å; R111-H178 HydrophobicContact CG-CB 4.16Å; R111-V182 HydrophobicContact CB-CG2 3.78Å; R111-V182 HydrophobicContact CG-CG2 4.22Å
112E98.4Very high94.2Very high95 Ų9561.4 Ų61.444%0.44434%0.343SS..EExtended strand (participates in β ladder)trans-83.8134.5166.2-58.8176-174.600108.7K86 I110 L129K86-E112 HydrophobicContact CB-CG 4.24Å; K86-E112 HydrophobicContact CD-CB 4.19Å; K86-E112 HydrophobicContact CD-CG 4.06Å; K86-E112 VanDerWaalsContact CD-OE2 3.3Å; K86-E112 WeakPolarHBondContact CD-OE2 3.24Å; K86-E112 WeakPolarHBondContact CE-OE2 3.24Å; K86-E112 HydrophobicContact CG-CB 4.22Å; K86-E112 HydrophobicContact CG-CG 4.17Å; K86-E112 IonicContact NZ-OE2 2.72Å; K86-E112 PolarHBondContact NZ-OE2 3.04Å; I110-E112 HydrophobicContact CG2-CG 4.42Å; E112-L129 HydrophobicContact CG-CD1 4.39Å
113V97.9Very high93.4Very high1 Ų163.5 Ų63.51%0.00635%0.352CS..EExtended strand (participates in β ladder)trans-121.4115178.4-174.90000107.8R111 Y115 I127 G128 V130 L175 H178R111-V113 HydrophobicContact CG-CG2 3.94Å; V113-Y115 HydrophobicContact CB-CE1 4.32Å; V113-Y115 HydrophobicContact CG1-CD1 3.92Å; V113-Y115 HydrophobicContact CG1-CE1 3.59Å; V113-I127 CarbonylContact O-C 3.54Å; V113-I127 WeakPolarHBondContact O-CA 3.18Å; V113-I127 WeakPolarHBondContact O-CB 3.16Å; V113-G128 PolarHBondContact N-O 3.27Å; V113-G128 PolarHBondContact O-N 3.49Å; V113-V130 HydrophobicContact CG2-CG2 4.45Å; V113-L175 HydrophobicContact CG2-CD1 4.26Å; V113-H178 VanDerWaalsContact CG1-CD2 3.42Å; V113-H178 WeakPolarHBondContact CG1-CD2 3.3Å; V113-H178 HydrophobicContact CG2-CB 3.52Å
114E96.9Very high93Very high99 Ų9958.5 Ų58.546%0.46333%0.326SS..EExtended strand (participates in β ladder)trans-96.4127.1173.1-63.3-179.6174.600108.4K86 T89 I127K86-E114 VanDerWaalsContact CE-OE1 3.28Å; K86-E114 WeakPolarHBondContact CE-OE1 3.23Å; K86-E114 IonicContact NZ-OE1 2.7Å; K86-E114 PolarHBondContact NZ-OE1 2.85Å; T89-E114 HydrophobicContact CG2-CB 3.9Å; T89-E114 VanDerWaalsContact CG2-CD 3.46Å; T89-E114 HydrophobicContact CG2-CG 3.61Å; E114-I127 HydrophobicContact CG-CG2 4.33Å
115Y96.2Very high92.9Very high1 Ų156.6 Ų56.60%0.00432%0.319CS..  trans-85.9-16.2177.6-53.7-41.1000112.7V113 M117 L122 N126 I127 G128 T156 L158 Q171 L174 L175V113-Y115 HydrophobicContact CB-CE1 4.32Å; V113-Y115 HydrophobicContact CG1-CD1 3.92Å; V113-Y115 HydrophobicContact CG1-CE1 3.59Å; Y115-M117 PolarHBondContact O-N 2.84Å; Y115-L122 WeakPolarHBondContact O-CB 3.18Å; Y115-N126 WeakPolarHBondContact CB-O 3.36Å; Y115-N126 HydrophobicContact CD2-CB 3.62Å; Y115-N126 WeakPolarHBondContact CD2-O 3.42Å; Y115-N126 HydrophobicContact CE2-CB 4.14Å; Y115-N126 PolarHBondContact N-O 2.91Å; Y115-I127 WeakPolarHBondContact CE2-O 3.22Å; Y115-I127 PolarHBondContact OH-O 3.41Å; Y115-G128 WeakPolarHBondContact OH-CA 3.44Å; Y115-G128 PolarHBondContact OH-N 3.29Å; Y115-T156 PolarHBondContact OH-OG1 2.95Å; Y115-L158 HydrophobicContact CE2-CD2 4.18Å; Y115-Q171 HydrophobicContact CD1-CB 4.34Å; Y115-Q171 HydrophobicContact CD2-CB 3.79Å; Y115-Q171 HydrophobicContact CD2-CG 3.61Å; Y115-Q171 WeakPolarHBondContact CE1-O 3.5Å; Y115-Q171 HydrophobicContact CE2-CB 4.01Å; Y115-Q171 HydrophobicContact CE2-CG 4.3Å; Y115-Q171 HydrophobicContact CG-CB 4Å; Y115-Q171 HydrophobicContact CG-CG 3.77Å; Y115-L174 HydrophobicContact CD1-CB 4.12Å; Y115-L174 HydrophobicContact CD1-CD1 4.15Å; Y115-L174 HydrophobicContact CE1-CB 4.41Å; Y115-L175 HydrophobicContact CE1-CB 4.09Å
116F94.3Very high92.9Very high60 Ų6057 Ų5726%0.26332%0.322SS..  trans-65.9118.1176.1-179.1-114.8000110.2T89 K90 P118 V123 C124T89-F116 HydrophobicContact CG2-CB 4.48Å; K90-F116 VanDerWaalsContact NZ-CE2 3.34Å; F116-P118 HydrophobicContact CD1-CG 4.18Å; F116-P118 HydrophobicContact CE1-CG 3.61Å; F116-P118 HydrophobicContact CZ-CG 4.09Å; F116-V123 HydrophobicContact CE2-CB 4.36Å; F116-C124 VanDerWaalsContact CA-O 3.3Å; F116-C124 WeakPolarHBondContact CA-O 3.47Å; F116-C124 VanDerWaalsContact CB-O 3.32Å; F116-C124 WeakPolarHBondContact CB-O 3.21Å; F116-C124 PolarHBondContact N-O 3.42Å
117M91Very high92.9Very high34 Ų3452.3 Ų52.317%0.16730%0.3CS..  trans-126.799.8178.1-165178.6-65.500109.6Y115 G119 T120 L122 L174 P243 A245 A246Y115-M117 PolarHBondContact O-N 2.84Å; M117-G119 PolarHBondContact O-N 2.76Å; M117-T120 HydrophobicContact CB-CG2 4.23Å; M117-T120 HydrophobicContact CG-CG2 3.82Å; M117-T120 PolarHBondContact O-N 2.84Å; M117-T120 PolarHBondContact O-OG1 2.99Å; M117-T120 HydrophobicContact SD-CG2 3.9Å; M117-L122 HydrophobicContact CB-CB 4.19Å; M117-L122 PolarHBondContact N-O 2.9Å; M117-L174 HydrophobicContact CE-CD2 4.26Å; M117-P243 HydrophobicContact CE-CG 4.43Å; M117-P243 HydrophobicContact SD-CB 4.38Å; M117-P243 HydrophobicContact SD-CG 3.55Å; M117-P243 VanDerWaalsContact SD-CG 3.55Å; M117-A245 HydrophobicContact CG-CB 4.47Å; M117-A245 HydrophobicContact SD-CB 3.65Å; M117-A246 HydrophobicContact CE-CB 3.79Å; M117-A246 HydrophobicContact SD-CB 4.37Å
118P88.4Confident92.9Very high96 Ų9649 Ų4962%0.62328%0.282SS*.THydrogen-bonded Turntrans-52138.4-178.3-25.231000112.9F116 T120F116-P118 HydrophobicContact CD1-CG 4.18Å; F116-P118 HydrophobicContact CE1-CG 3.61Å; F116-P118 HydrophobicContact CZ-CG 4.09Å; P118-T120 VanDerWaalsContact C-N 3.29Å; P118-T120 PolarHBondContact O-N 2.81Å
119G87.3Confident93Very high88 Ų8845.8 Ų45.891%0.90726%0.262SS*.THydrogen-bonded Turntrans79.55.5178.500000115M117M117-G119 PolarHBondContact O-N 2.76Å
120T88.4Confident93.1Very high30 Ų3040.9 Ų40.918%0.18424%0.241CC..SBendtrans-119179.2177.978.10000111.6M117 P118 L122 V123 P243 A245M117-T120 HydrophobicContact CB-CG2 4.23Å; M117-T120 HydrophobicContact CG-CG2 3.82Å; M117-T120 PolarHBondContact O-N 2.84Å; M117-T120 PolarHBondContact O-OG1 2.99Å; M117-T120 HydrophobicContact SD-CG2 3.9Å; P118-T120 VanDerWaalsContact C-N 3.29Å; P118-T120 PolarHBondContact O-N 2.81Å; T120-L122 PolarHBondContact O-N 3.48Å; T120-L122 PolarHBondContact OG1-N 2.85Å; T120-L122 VanDerWaalsContact OG1-N 3.08Å; T120-V123 WeakPolarHBondContact O-CG1 3.47Å; T120-P243 HydrophobicContact CG2-CB 3.6Å; T120-P243 HydrophobicContact CG2-CG 3.87Å; T120-A245 HydrophobicContact CG2-CB 4.47Å
121S80Confident93.1Very high83 Ų8337.8 Ų37.858%0.5823%0.225SC*.SBendtrans-67.4-15.8171520000113.4V123S121-V123 VanDerWaalsContact C-N 3.3Å; S121-V123 PolarHBondContact O-N 2.93Å
122L86.2Confident93.1Very high2 Ų235 Ų351%0.0122%0.215CC..  trans-84.769.5-179.8-60.6172.7000111.4Y115 M117 T120 C124 V167 C170 L174 P243Y115-L122 WeakPolarHBondContact O-CB 3.18Å; M117-L122 HydrophobicContact CB-CB 4.19Å; M117-L122 PolarHBondContact N-O 2.9Å; T120-L122 PolarHBondContact O-N 3.48Å; T120-L122 PolarHBondContact OG1-N 2.85Å; T120-L122 VanDerWaalsContact OG1-N 3.08Å; L122-C124 VanDerWaalsContact C-N 3.32Å; L122-V167 HydrophobicContact CD2-CG1 4.16Å; L122-C170 HydrophobicContact CD1-CB 4.28Å; L122-C170 HydrophobicContact CD2-CB 3.37Å; L122-C170 HydrophobicContact CG-CB 4.38Å; L122-L174 HydrophobicContact CD1-CD1 3.76Å; L122-P243 HydrophobicContact CD1-CG 3.89Å
123V80.8Confident93Very high87 Ų8730.4 Ų30.453%0.52719%0.194SC..  trans-91.810.2180-64.80000113.9K90 F116 T120 S121K90-V123 PolarHBondContact NZ-O 3.49Å; F116-V123 HydrophobicContact CE2-CB 4.36Å; T120-V123 WeakPolarHBondContact O-CG1 3.47Å; S121-V123 VanDerWaalsContact C-N 3.3Å; S121-V123 PolarHBondContact O-N 2.93Å
124C88Confident92.9Very high17 Ų1734.7 Ų34.712%0.11521%0.212CC..  trans-86.1142.5-174.8-58.70000112.6F116 L122 N126 V167F116-C124 VanDerWaalsContact CA-O 3.3Å; F116-C124 WeakPolarHBondContact CA-O 3.47Å; F116-C124 VanDerWaalsContact CB-O 3.32Å; F116-C124 WeakPolarHBondContact CB-O 3.21Å; F116-C124 PolarHBondContact N-O 3.42Å; L122-C124 VanDerWaalsContact C-N 3.32Å; C124-N126 VanDerWaalsContact C-N 3.32Å; C124-N126 PolarHBondContact O-N 3.2Å; C124-V167 VanDerWaalsContact SG-CG1 3.57Å
125D92.9Very high92.7Very high23 Ų2330.2 Ų30.212%0.12319%0.192CC..  trans-89.12.9-173.1-59.2-48.9000114.6K88 T89 K90 K92K88-D125 WeakPolarHBondContact CA-O 3.37Å; K88-D125 WeakPolarHBondContact CB-O 3.28Å; K88-D125 WeakPolarHBondContact CG-O 3.45Å; T89-D125 PolarHBondContact N-O 2.9Å; T89-D125 WeakPolarHBondContact OG1-CA 3.47Å; T89-D125 WeakPolarHBondContact OG1-CB 3.32Å; T89-D125 PolarHBondContact OG1-O 3.22Å; T89-D125 PolarHBondContact OG1-OD1 3.31Å; K90-D125 WeakPolarHBondContact CD-OD1 3.39Å; K90-D125 WeakPolarHBondContact CE-OD1 3.28Å; K90-D125 WeakPolarHBondContact CG-OD1 3.38Å; K90-D125 IonicContact NZ-OD1 3.3Å; K90-D125 PolarHBondContact NZ-OD1 3.06Å; K90-D125 IonicContact NZ-OD2 2.65Å; K92-D125 VanDerWaalsContact CE-OD2 3.28Å; K92-D125 WeakPolarHBondContact CE-OD2 3.44Å; K92-D125 HydrophobicContact CG-CB 3.68Å
126N97Very high92.4Very high14 Ų1433 Ų338%0.07521%0.206CC..  trans-64157.1-179.4-61.790.1000111.3Y115 C124 H157 L158 Q171Y115-N126 WeakPolarHBondContact CB-O 3.36Å; Y115-N126 HydrophobicContact CD2-CB 3.62Å; Y115-N126 WeakPolarHBondContact CD2-O 3.42Å; Y115-N126 HydrophobicContact CE2-CB 4.14Å; Y115-N126 PolarHBondContact N-O 2.91Å; C124-N126 VanDerWaalsContact C-N 3.32Å; C124-N126 PolarHBondContact O-N 3.2Å; N126-H157 WeakPolarHBondContact CB-O 3.49Å; N126-H157 PolarHBondContact ND2-O 2.91Å; N126-L158 VanDerWaalsContact ND2-C 3.29Å; N126-L158 PolarHBondContact ND2-O 3.32Å; N126-L158 VanDerWaalsContact ND2-O 3.07Å; N126-Q171 PolarHBondContact OD1-NE2 3.29Å
127I98.1Very high91.5Very high0 Ų032.3 Ų32.30%022%0.216CC..EExtended strand (participates in β ladder)trans-137.2163.7-175.359.482.7000111.2K86 K88 T89 C96 V113 E114 Y115 T156K86-I127 HydrophobicContact CB-CD1 4.06Å; K86-I127 HydrophobicContact CG-CB 4.15Å; K86-I127 HydrophobicContact CG-CD1 3.96Å; K86-I127 HydrophobicContact CG-CG1 4Å; K86-I127 HydrophobicContact CG-CG2 4.3Å; K86-I127 WeakPolarHBondContact O-CD1 3.18Å; K88-I127 HydrophobicContact CG-CG1 4.14Å; T89-I127 HydrophobicContact CG2-CG2 4.28Å; C96-I127 HydrophobicContact CB-CD1 3.58Å; C96-I127 VanDerWaalsContact SG-CD1 3.58Å; V113-I127 CarbonylContact O-C 3.54Å; V113-I127 WeakPolarHBondContact O-CA 3.18Å; V113-I127 WeakPolarHBondContact O-CB 3.16Å; E114-I127 HydrophobicContact CG-CG2 4.33Å; Y115-I127 WeakPolarHBondContact CE2-O 3.22Å; Y115-I127 PolarHBondContact OH-O 3.41Å; I127-T156 PolarHBondContact O-OG1 3.44Å
128G98.4Very high89.9Confident0 Ų040.1 Ų40.10%025%0.249CC..EExtended strand (participates in β ladder)trans-120.7145.6161.800000110.4V113 Y115 N155V113-G128 PolarHBondContact N-O 3.27Å; V113-G128 PolarHBondContact O-N 3.49Å; Y115-G128 WeakPolarHBondContact OH-CA 3.44Å; Y115-G128 PolarHBondContact OH-N 3.29Å; G128-N155 CarbonylContact C-O 3.56Å; G128-N155 WeakPolarHBondContact CA-O 3.33Å
129L98.8Very high88.2Confident0 Ų043.2 Ų43.20%026%0.256CS..EExtended strand (participates in β ladder)trans-121.5112.2175179.261.6000108.4A84 K86 C96 I110 E112 N155A84-L129 HydrophobicContact CB-CD1 4.46Å; A84-L129 HydrophobicContact CB-CD2 4.25Å; A84-L129 WeakPolarHBondContact O-CD2 3.15Å; K86-L129 HydrophobicContact CB-CD1 4.23Å; C96-L129 HydrophobicContact CB-CB 4.39Å; C96-L129 WeakPolarHBondContact O-CD2 3.4Å; I110-L129 HydrophobicContact CG2-CD1 3.8Å; E112-L129 HydrophobicContact CG-CD1 4.39Å; L129-N155 PolarHBondContact N-O 3.22Å; L129-N155 PolarHBondContact O-N 3.3Å
130V98.9Very high86.6Confident0 Ų041.6 Ų41.60%023%0.229CC..EExtended strand (participates in β ladder)trans-110125.7179.8-177.80000109I110 R111 V113 V152 V153 A154 L175 L179 V182I110-V130 CarbonylContact C-O 3.53Å; I110-V130 WeakPolarHBondContact CA-O 3.01Å; R111-V130 HydrophobicContact CB-CB 4.15Å; R111-V130 PolarHBondContact N-O 3.36Å; R111-V130 PolarHBondContact O-N 2.88Å; V113-V130 HydrophobicContact CG2-CG2 4.45Å; V130-V152 HydrophobicContact CG1-CG1 3.4Å; V130-V152 VanDerWaalsContact CG1-CG1 3.4Å; V130-V153 CarbonylContact C-O 3.46Å; V130-V153 WeakPolarHBondContact CA-O 3.18Å; V130-A154 HydrophobicContact CG2-CB 3.95Å; V130-L175 HydrophobicContact CG2-CD1 3.8Å; V130-L179 HydrophobicContact CG1-CD1 3.77Å; V130-L179 HydrophobicContact CG2-CD1 4.43Å; V130-V182 HydrophobicContact CG1-CB 4.24Å; V130-V182 HydrophobicContact CG1-CG1 4.1Å; V130-V182 HydrophobicContact CG1-CG2 4.38Å
131V98.8Very high84.7Confident0 Ų046.9 Ų46.90%026%0.262CS..EExtended strand (participates in β ladder)trans-119131.8175.5-58.70000109.9A84 T98 W100 L107 K109 I110 L133 V152 V153A84-V131 HydrophobicContact CB-CG1 4.31Å; T98-V131 HydrophobicContact CG2-CG2 3.76Å; W100-V131 HydrophobicContact CZ3-CG1 4.19Å; L107-V131 HydrophobicContact CD1-CB 4.47Å; K109-V131 WeakPolarHBondContact O-CA 3.32Å; I110-V131 HydrophobicContact CG1-CG1 4.3Å; V131-L133 HydrophobicContact CB-CD2 4.42Å; V131-L133 HydrophobicContact CG2-CD1 4.17Å; V131-L133 HydrophobicContact CG2-CD2 4.33Å; V131-L133 HydrophobicContact CG2-CG 4.05Å; V131-V152 CarbonylContact O-C 3.57Å; V131-V152 WeakPolarHBondContact O-CA 3.46Å; V131-V153 HydrophobicContact CG2-CB 3.91Å; V131-V153 PolarHBondContact N-O 3.16Å; V131-V153 PolarHBondContact O-N 3.46Å
132C98.2Very high83.3Confident4 Ų445.4 Ų45.43%0.02725%0.251CS..EExtended strand (participates in β ladder)trans-98.6121.3168.4-172.60000107.7V108 K109 V152 V182V108-C132 HydrophobicContact CB-CB 4.22Å; V108-C132 WeakPolarHBondContact CB-O 3.47Å; V108-C132 PolarHBondContact N-O 2.91Å; K109-C132 HydrophobicContact CB-CB 4.11Å; K109-C132 PolarHBondContact N-O 3.24Å; K109-C132 PolarHBondContact O-N 3.49Å; C132-V152 HydrophobicContact CB-CG2 4.36Å; C132-V182 HydrophobicContact CB-CG1 3.99Å
133L97.4Very high81.4Confident0 Ų051.3 Ų51.30%029%0.293CS..EExtended strand (participates in β ladder)trans-119.4132.3-175.6-60.4178.5000109.6I57 W100 F105 E106 L107 V131 E150 I151I57-L133 HydrophobicContact CD1-CD1 3.86Å; I57-L133 HydrophobicContact CG1-CD1 4.46Å; W100-L133 HydrophobicContact CB-CD1 3.94Å; W100-L133 HydrophobicContact CD2-CD1 4.27Å; W100-L133 HydrophobicContact CD2-CD2 3.7Å; W100-L133 HydrophobicContact CE3-CD1 4.49Å; W100-L133 HydrophobicContact CE3-CD2 4.09Å; W100-L133 HydrophobicContact CG-CD1 4.04Å; W100-L133 HydrophobicContact CG-CD2 4.01Å; W100-L133 HydrophobicContact CZ2-CD2 4.33Å; F105-L133 HydrophobicContact CB-CB 4.23Å; F105-L133 HydrophobicContact CB-CD1 4.2Å; F105-L133 HydrophobicContact CD1-CB 4.05Å; F105-L133 HydrophobicContact CD1-CD1 4.28Å; F105-L133 HydrophobicContact CG-CB 4.47Å; F105-L133 HydrophobicContact CG-CD1 4.2Å; E106-L133 CarbonylContact O-C 3.58Å; E106-L133 WeakPolarHBondContact O-CA 3.46Å; L107-L133 HydrophobicContact CD1-CD2 4Å; V131-L133 HydrophobicContact CB-CD2 4.42Å; V131-L133 HydrophobicContact CG2-CD1 4.17Å; V131-L133 HydrophobicContact CG2-CD2 4.33Å; V131-L133 HydrophobicContact CG2-CG 4.05Å; L133-E150 CarbonylContact O-C 3.56Å; L133-E150 VanDerWaalsContact O-CA 3.25Å; L133-E150 WeakPolarHBondContact O-CA 3.23Å; L133-I151 HydrophobicContact CB-CG2 4.16Å; L133-I151 PolarHBondContact N-O 3.44Å; L133-I151 PolarHBondContact O-N 3.24Å
134K94.8Very high79.9Confident90 Ų9051.4 Ų51.439%0.39129%0.29SS..EExtended strand (participates in β ladder)trans-83.1122.3167-179.8-178173.1-165.10108.5F105 E106 V108 L136 H149 E150F105-K134 VanDerWaalsContact CA-O 3.32Å; F105-K134 WeakPolarHBondContact CA-O 3.44Å; E106-K134 HydrophobicContact CB-CB 4.34Å; E106-K134 PolarHBondContact N-O 3.17Å; E106-K134 PolarHBondContact O-N 3.05Å; E106-K134 IonicContact OE2-NZ 3.47Å; V108-K134 HydrophobicContact CG2-CB 3.74Å; K134-L136 PolarHBondContact O-N 3.05Å; K134-H149 CarbonylContact C-O 3.52Å; K134-H149 WeakPolarHBondContact CA-O 3.31Å; K134-E150 HydrophobicContact CB-CG 4.43Å
135V93Very high78.1Confident5 Ų555.4 Ų55.43%0.0332%0.316CS..EExtended strand (participates in β ladder)trans-72.9120.6174.7-169.50000108.7I7 F105 H149 I151 F373I7-V135 HydrophobicContact CB-CG1 4.22Å; I7-V135 HydrophobicContact CD1-CG1 3.71Å; I7-V135 HydrophobicContact CG2-CG1 3.86Å; F105-V135 HydrophobicContact CD1-CG2 4.31Å; F105-V135 HydrophobicContact CE1-CB 4.45Å; F105-V135 HydrophobicContact CE1-CG1 4.27Å; F105-V135 HydrophobicContact CE1-CG2 3.99Å; V135-H149 HydrophobicContact CB-CB 4.39Å; V135-H149 WeakPolarHBondContact CB-O 3.49Å; V135-H149 WeakPolarHBondContact CG2-O 2.99Å; V135-H149 PolarHBondContact N-O 2.98Å; V135-I151 HydrophobicContact CG2-CB 4.5Å; V135-I151 HydrophobicContact CG2-CG2 3.99Å; V135-F373 HydrophobicContact CG2-CD1 4.3Å; V135-F373 HydrophobicContact CG2-CD2 4.1Å; V135-F373 HydrophobicContact CG2-CE1 4.4Å; V135-F373 HydrophobicContact CG2-CE2 4.19Å; V135-F373 HydrophobicContact CG2-CG 4.15Å; V135-F373 HydrophobicContact CG2-CZ 4.34Å
136L89.3Confident76Confident59 Ų5960.2 Ų60.231%0.30934%0.342SS..PPolyproline II helixtrans-85.8132.9179.5-55.8179.5000109.7K104 E106 K134K104-L136 WeakPolarHBondContact O-CB 3.27Å; K104-L136 PolarHBondContact O-N 3.39Å; E106-L136 HydrophobicContact CB-CD1 4.46Å; E106-L136 HydrophobicContact CB-CD2 3.9Å; E106-L136 HydrophobicContact CB-CG 4.43Å; K134-L136 PolarHBondContact O-N 3.05Å
137G76Confident74Confident46 Ų4661.4 Ų61.447%0.47435%0.348SS..  trans-158.2174.1-176.900000111.6E139G137-E139 PolarHBondContact O-N 3.16Å
138K57.8Low72.5Confident198 Ų19865.2 Ų65.286%0.86137%0.368SS*.SBendtrans-64.6113.3177.9-70.7-174179.1-1790109.1
139E53.2Low71.8Confident161 Ų16166 Ų6675%0.75237%0.372SS*.  trans0.8111.1174-70.3-69.4161.200114.8G137 T141G137-E139 PolarHBondContact O-N 3.16Å; E139-T141 PolarHBondContact O-N 3.41Å
140P51.7Low71.5Confident54 Ų5466.7 Ų66.735%0.35138%0.375SS..  trans-59.3112.6168.223.5-28.7000108.1S142P140-S142 PolarHBondContact O-N 3.44Å
141T49.9Very low71.3Confident142 Ų14266.7 Ų66.787%0.87138%0.375SS*.SBendtrans-60.9-4.8175.948.10000113.4E139E139-T141 PolarHBondContact O-N 3.41Å
142S49.3Very low71.3Confident51 Ų5166.7 Ų66.736%0.35738%0.375SS..SBendtrans-117.9121.218055.50000111.4P140 N144 L147P140-S142 PolarHBondContact O-N 3.44Å; S142-N144 PolarHBondContact O-N 2.89Å; S142-L147 WeakPolarHBondContact OG-CD1 3.44Å
143S47.9Very low71.3Confident126 Ų12666.5 Ų66.588%0.88137%0.374SS*.  trans-67.733173.760.40000114.2P145S143-P145 WeakPolarHBondContact O-CD 3.33Å
144N49.4Very low71.4Confident89 Ų8966.5 Ų66.548%0.47637%0.374SS..  trans-89.7108.7-177.2-160-4.5000109.6S142 D146 L147S142-N144 PolarHBondContact O-N 2.89Å; N144-D146 PolarHBondContact O-N 3.07Å; N144-D146 VanDerWaalsContact O-N 3.16Å; N144-L147 HydrophobicContact CB-CD1 3.71Å; N144-L147 HydrophobicContact CB-CG 4.11Å; N144-L147 VanDerWaalsContact O-CB 3.31Å; N144-L147 WeakPolarHBondContact O-CB 3.49Å; N144-L147 PolarHBondContact O-N 2.83Å
145P48.7Very low71.6Confident101 Ų10162.2 Ų62.266%0.65636%0.355SS*.G310 helixtrans-62.1-20.7-178.123.7-33000113.6S143 L147 N148S143-P145 WeakPolarHBondContact O-CD 3.33Å; P145-L147 PolarHBondContact O-N 3.34Å; P145-L147 VanDerWaalsContact O-N 3.15Å; P145-N148 PolarHBondContact O-N 2.86Å; P145-N148 PolarHBondContact O-OD1 2.94Å
146D50.3Low71.9Confident125 Ų12562 Ų6267%0.66835%0.354SS*.G310 helixtrans-72.40.4173.8-76.4-20.6000114.1N144 K318N144-D146 PolarHBondContact O-N 3.07Å; N144-D146 VanDerWaalsContact O-N 3.16Å; D146-K318 PolarHBondContact O-NZ 2.76Å
147L54.5Low72.3Confident38 Ų3859.6 Ų59.620%0.19934%0.341CS..G310 helixtrans-96.328.1173.6-67.7166.3000112.4S142 N144 P145 H149S142-L147 WeakPolarHBondContact OG-CD1 3.44Å; N144-L147 HydrophobicContact CB-CD1 3.71Å; N144-L147 HydrophobicContact CB-CG 4.11Å; N144-L147 VanDerWaalsContact O-CB 3.31Å; N144-L147 WeakPolarHBondContact O-CB 3.49Å; N144-L147 PolarHBondContact O-N 2.83Å; P145-L147 PolarHBondContact O-N 3.34Å; P145-L147 VanDerWaalsContact O-N 3.15Å; L147-H149 PolarHBondContact O-CD2 3.49Å; L147-H149 PolarHBondContact O-CE1 2.85Å; L147-H149 PolarHBondContact O-N 3.09Å; L147-H149 PolarHBondContact O-ND1 3.28Å
148N65.6Low73.3Confident81 Ų8157.4 Ų57.443%0.43332%0.318SS..  trans-51.6103.8168.9-84.410.1000109.3P145 E150P145-N148 PolarHBondContact O-N 2.86Å; P145-N148 PolarHBondContact O-OD1 2.94Å; N148-E150 HydrophobicContact CB-CG 3.95Å; N148-E150 PolarHBondContact ND2-OE1 2.79Å; N148-E150 PolarHBondContact ND2-OE2 2.89Å; N148-E150 PolarHBondContact O-N 2.84Å
149H84.3Confident75.2Confident17 Ų1748.8 Ų48.88%0.07928%0.282CS..  trans-7659.2178.7-62.8-53.2000107.8K134 V135 L147 F373 H375K134-H149 CarbonylContact C-O 3.52Å; K134-H149 WeakPolarHBondContact CA-O 3.31Å; V135-H149 HydrophobicContact CB-CB 4.39Å; V135-H149 WeakPolarHBondContact CB-O 3.49Å; V135-H149 WeakPolarHBondContact CG2-O 2.99Å; V135-H149 PolarHBondContact N-O 2.98Å; L147-H149 PolarHBondContact O-CD2 3.49Å; L147-H149 PolarHBondContact O-CE1 2.85Å; L147-H149 PolarHBondContact O-N 3.09Å; L147-H149 PolarHBondContact O-ND1 3.28Å; H149-F373 HydrophobicContact CB-CE1 3.89Å; H149-F373 HydrophobicContact CB-CZ 4.23Å; H149-F373 AromaticContact ND1-CE1 3.86Å; H149-H375 AromaticContact CD2-ND1 3.86Å; H149-H375 AromaticContact CE1-CG 3.74Å; H149-H375 AromaticContact CE1-ND1 3.03Å; H149-H375 PolarHBondContact CE1-ND1 3.32Å; H149-H375 AromaticContact CG-ND1 3.84Å; H149-H375 AromaticContact ND1-ND1 3.3Å; H149-H375 PolarHBondContact ND1-ND1 3.28Å; H149-H375 AromaticContact NE2-ND1 3.35Å; H149-H375 PolarHBondContact NE2-ND1 3.37Å
150E92.3Very high77.1Confident14 Ų1448.1 Ų48.17%0.06528%0.277CS..EExtended strand (participates in β ladder)trans-108.6136.8-172.5-68.4172.6163.500109.6V108 L133 K134 N148 R191V108-E150 HydrophobicContact CG2-CG 4.24Å; L133-E150 CarbonylContact O-C 3.56Å; L133-E150 VanDerWaalsContact O-CA 3.25Å; L133-E150 WeakPolarHBondContact O-CA 3.23Å; K134-E150 HydrophobicContact CB-CG 4.43Å; N148-E150 HydrophobicContact CB-CG 3.95Å; N148-E150 PolarHBondContact ND2-OE1 2.79Å; N148-E150 PolarHBondContact ND2-OE2 2.89Å; N148-E150 PolarHBondContact O-N 2.84Å; E150-R191 IonicContact OE2-CZ 2.74Å; E150-R191 IonicContact OE2-NE 2.78Å; E150-R191 PolarHBondContact OE2-NE 2.76Å; E150-R191 IonicContact OE2-NH2 3.55Å; E150-R191 PolarHBondContact OE2-NH2 2.83Å
151I95.8Very high79.1Confident0 Ų048.1 Ų48.10%027%0.274CS..EExtended strand (participates in β ladder)trans-120.8142.2171-173.2169.2000108.7F9 F105 L133 V135 P192 I194 L334 F373F9-I151 HydrophobicContact CE1-CD1 4.25Å; F9-I151 HydrophobicContact CE2-CD1 4.31Å; F9-I151 HydrophobicContact CZ-CD1 3.5Å; F105-I151 HydrophobicContact CE1-CG2 4.32Å; L133-I151 HydrophobicContact CB-CG2 4.16Å; L133-I151 PolarHBondContact N-O 3.44Å; L133-I151 PolarHBondContact O-N 3.24Å; V135-I151 HydrophobicContact CG2-CB 4.5Å; V135-I151 HydrophobicContact CG2-CG2 3.99Å; I151-P192 HydrophobicContact CG1-CB 4.31Å; I151-I194 HydrophobicContact CD1-CD1 3.71Å; I151-I194 HydrophobicContact CD1-CG1 4.07Å; I151-L334 HydrophobicContact CD1-CD1 3.94Å; I151-L334 HydrophobicContact CD1-CD2 3.96Å; I151-F373 HydrophobicContact CB-CE2 4.49Å
152V98Very high81.2Confident0 Ų046 Ų460%025%0.254CS..EExtended strand (participates in β ladder)trans-107.1126.3175.5-172.20000109.1V130 V131 C132 L179 V182 A183 R191 P192 V193 I194V130-V152 HydrophobicContact CG1-CG1 3.4Å; V130-V152 VanDerWaalsContact CG1-CG1 3.4Å; V131-V152 CarbonylContact O-C 3.57Å; V131-V152 WeakPolarHBondContact O-CA 3.46Å; C132-V152 HydrophobicContact CB-CG2 4.36Å; V152-L179 HydrophobicContact CB-CD1 4.42Å; V152-L179 HydrophobicContact CG1-CD1 3.54Å; V152-V182 HydrophobicContact CG1-CB 4.45Å; V152-V182 HydrophobicContact CG1-CG1 3.82Å; V152-V182 HydrophobicContact CG2-CG1 4.2Å; V152-A183 HydrophobicContact CB-CB 4.47Å; V152-A183 HydrophobicContact CG2-CB 4.01Å; V152-R191 HydrophobicContact CG2-CB 4.23Å; V152-P192 PolarHBondContact N-O 2.96Å; V152-V193 HydrophobicContact CB-CG2 4.33Å; V152-V193 CarbonylContact O-C 3.53Å; V152-V193 VanDerWaalsContact O-CA 3.24Å; V152-V193 WeakPolarHBondContact O-CA 3.08Å; V152-I194 PolarHBondContact O-N 2.93Å
153V98.8Very high83.4Confident0 Ų050.9 Ų50.90%026%0.264CS..EExtended strand (participates in β ladder)trans-114.6126.1177.9-178.90000108.7L11 I57 C59 V130 V131 I194L11-V153 HydrophobicContact CD1-CG1 3.73Å; L11-V153 HydrophobicContact CD1-CG2 4.13Å; I57-V153 HydrophobicContact CD1-CG2 4.15Å; I57-V153 HydrophobicContact CG2-CG1 4.48Å; C59-V153 WeakPolarHBondContact SG-CG1 3.35Å; V130-V153 CarbonylContact C-O 3.46Å; V130-V153 WeakPolarHBondContact CA-O 3.18Å; V131-V153 HydrophobicContact CG2-CB 3.91Å; V131-V153 PolarHBondContact N-O 3.16Å; V131-V153 PolarHBondContact O-N 3.46Å; V153-I194 CarbonylContact C-O 3.59Å; V153-I194 WeakPolarHBondContact CA-O 3.48Å
154A98.9Very high85.6Confident0 Ų047 Ų470%023%0.234CC..EExtended strand (participates in β ladder)trans-114.2127.3176.300000110V130 L179 I194 L195 C196V130-A154 HydrophobicContact CG2-CB 3.95Å; A154-L179 HydrophobicContact CB-CD1 3.9Å; A154-L179 HydrophobicContact CB-CD2 3.88Å; A154-L179 HydrophobicContact CB-CG 4.48Å; A154-I194 PolarHBondContact N-O 2.84Å; A154-L195 HydrophobicContact CB-CD1 3.68Å; A154-C196 PolarHBondContact O-N 3.4Å
155N98.9Very high87.8Confident0 Ų042.8 Ų42.80%021%0.211CC..EExtended strand (participates in β ladder)trans-115.6134.1175.1179.82.1000109.1C59 L60 Q61 A97 G128 L129 C196C59-N155 HydrophobicContact CB-CB 3.95Å; L60-N155 PolarHBondContact N-ND2 2.83Å; L60-N155 PolarHBondContact O-ND2 2.92Å; Q61-N155 PolarHBondContact NE2-OD1 3.38Å; A97-N155 PolarHBondContact O-ND2 3.04Å; G128-N155 CarbonylContact C-O 3.56Å; G128-N155 WeakPolarHBondContact CA-O 3.33Å; L129-N155 PolarHBondContact N-O 3.22Å; L129-N155 PolarHBondContact O-N 3.3Å; N155-C196 WeakPolarHBondContact CA-O 3.24Å
156T98.8Very high90Very high0 Ų039.2 Ų39.20%019%0.186CC..EExtended strand (participates in β ladder)trans-145.8159.9174.6-170.70000112.8Q61 Y115 I127 L158 L175 C196 G197 D198 F199Q61-T156 WeakPolarHBondContact CG-O 3.44Å; Y115-T156 PolarHBondContact OH-OG1 2.95Å; I127-T156 PolarHBondContact O-OG1 3.44Å; T156-L158 HydrophobicContact CG2-CD2 4.11Å; T156-L158 HydrophobicContact CG2-CG 4.36Å; T156-L175 HydrophobicContact CG2-CD2 3.84Å; T156-C196 PolarHBondContact N-O 2.83Å; T156-C196 VanDerWaalsContact N-O 3.15Å; T156-G197 VanDerWaalsContact O-CA 3.3Å; T156-G197 WeakPolarHBondContact O-CA 3.44Å; T156-D198 PolarHBondContact O-N 3.47Å; T156-D198 VanDerWaalsContact O-N 3.15Å; T156-F199 HydrophobicContact CG2-CE2 4.43Å; T156-F199 HydrophobicContact CG2-CZ 4.19Å
157H98.5Very high92.2Very high8 Ų833.9 Ų33.94%0.03716%0.158CC..EExtended strand (participates in β ladder)trans-130.4107.4164.9178.3-171.7000107.8Q61 E62 K88 N126 D198 N200Q61-H157 HydrophobicContact CB-CB 4.03Å; Q61-H157 HydrophobicContact CG-CB 4.04Å; E62-H157 WeakPolarHBondContact CG-ND1 3.39Å; E62-H157 IonicContact OE1-CE1 2.82Å; E62-H157 PolarHBondContact OE1-CE1 3.22Å; E62-H157 IonicContact OE1-ND1 2.92Å; K88-H157 PolarHBondContact NZ-CE1 2.99Å; K88-H157 PolarHBondContact NZ-ND1 3.33Å; N126-H157 WeakPolarHBondContact CB-O 3.49Å; N126-H157 PolarHBondContact ND2-O 2.91Å; H157-D198 CarbonylContact C-O 3.58Å; H157-D198 WeakPolarHBondContact CA-O 3.31Å; H157-D198 IonicContact CD2-OD2 3.84Å; H157-D198 IonicContact NE2-OD2 3.11Å; H157-N200 PolarHBondContact CD2-ND2 3.1Å; H157-N200 PolarHBondContact NE2-ND2 3.25Å
158L97.8Very high94.2Very high0 Ų032 Ų320%015%0.149CC..  trans-74.8172-177.8-59.5-170.9000112.4Y115 N126 T156 F160 K168 Q171 V172 D198 F199 N200 L207Y115-L158 HydrophobicContact CE2-CD2 4.18Å; N126-L158 VanDerWaalsContact ND2-C 3.29Å; N126-L158 PolarHBondContact ND2-O 3.32Å; N126-L158 VanDerWaalsContact ND2-O 3.07Å; T156-L158 HydrophobicContact CG2-CD2 4.11Å; T156-L158 HydrophobicContact CG2-CG 4.36Å; L158-F160 PolarHBondContact O-N 3.32Å; L158-K168 HydrophobicContact CD1-CB 4.38Å; L158-Q171 HydrophobicContact CD2-CB 3.76Å; L158-V172 HydrophobicContact CD1-CG2 3.47Å; L158-V172 VanDerWaalsContact CD1-CG2 3.47Å; L158-V172 HydrophobicContact CD2-CG2 4.28Å; L158-D198 PolarHBondContact N-O 3.44Å; L158-F199 WeakPolarHBondContact CB-O 3.33Å; L158-F199 HydrophobicContact CD1-CB 4.03Å; L158-F199 HydrophobicContact CD1-CD1 3.66Å; L158-F199 HydrophobicContact CD1-CE1 4.45Å; L158-F199 HydrophobicContact CD1-CG 4.14Å; L158-F199 WeakPolarHBondContact CD1-O 3.44Å; L158-F199 HydrophobicContact CG-CD1 4.44Å; L158-N200 PolarHBondContact O-ND2 3.47Å; L158-L207 HydrophobicContact CD1-CD1 4.35Å
159L96.5Very high95.7Very high17 Ų1728.2 Ų28.29%0.08913%0.128CC..  trans-60.8132.6178.2178.866.8000111.5N161 L164 V167 K168 N200L159-N161 HydrophobicContact CD1-CB 4.49Å; L159-N161 HydrophobicContact CD2-CB 4.21Å; L159-N161 HydrophobicContact CG-CB 4.12Å; L159-L164 HydrophobicContact CD2-CB 3.64Å; L159-L164 HydrophobicContact CD2-CD1 3.83Å; L159-L164 HydrophobicContact CD2-CG 4.39Å; L159-V167 HydrophobicContact CD2-CB 4.09Å; L159-V167 HydrophobicContact CD2-CG1 3.93Å; L159-K168 HydrophobicContact CB-CG 4.16Å; L159-K168 WeakPolarHBondContact O-CD 3.2Å; L159-K168 WeakPolarHBondContact O-CE 3.19Å; L159-K168 PolarHBondContact O-NZ 3.4Å; L159-K168 VanDerWaalsContact O-NZ 3.16Å; L159-N200 WeakPolarHBondContact O-CB 3.3Å
160F94.1Very high96.3Very high147 Ų14727.6 Ų27.665%0.64513%0.126SC*.  trans-68.4-36.3178.879.1-84.4000113.5L158 E162 K168L158-F160 PolarHBondContact O-N 3.32Å; F160-E162 PolarHBondContact O-N 3.5Å; F160-K168 PolarHBondContact O-NZ 2.8Å
161N93.8Very high96.6Very high55 Ų5527 Ų2729%0.29412%0.123SC..  trans-59.1111.6-171-172.9-28.1000112.3L159 R163 L164 K168L159-N161 HydrophobicContact CD1-CB 4.49Å; L159-N161 HydrophobicContact CD2-CB 4.21Å; L159-N161 HydrophobicContact CG-CB 4.12Å; N161-R163 PolarHBondContact O-N 2.88Å; N161-R163 WeakPolarHBondContact OD1-CB 3.32Å; N161-R163 PolarHBondContact OD1-N 2.73Å; N161-L164 HydrophobicContact CB-CB 4.37Å; N161-L164 HydrophobicContact CB-CD1 4.15Å; N161-L164 HydrophobicContact CB-CG 4.36Å; N161-L164 PolarHBondContact O-N 3.36Å; N161-L164 VanDerWaalsContact O-N 3.12Å; N161-K168 WeakPolarHBondContact O-CE 3.45Å
162E93.7Very high96.7Very high97 Ų9727 Ų2745%0.45312%0.123SC..THydrogen-bonded Turntrans-62.2-26.2-176.2-55.4173.8171.300113.3F160 L164 Q229F160-E162 PolarHBondContact O-N 3.5Å; E162-L164 VanDerWaalsContact C-N 3.3Å; E162-L164 PolarHBondContact O-N 3.38Å; E162-Q229 HydrophobicContact CB-CB 3.92Å; E162-Q229 HydrophobicContact CG-CB 3.66Å
163R94.3Very high96.7Very high153 Ų15327 Ų2758%0.57712%0.123SC*.THydrogen-bonded Turntrans-84.4-2.8-179.7-59.5-179.7-1771710.7113.4N161 R223 H224N161-R163 PolarHBondContact O-N 2.88Å; N161-R163 WeakPolarHBondContact OD1-CB 3.32Å; N161-R163 PolarHBondContact OD1-N 2.73Å; R163-R223 PolarHBondContact O-NE 3.45Å; R163-H224 PolarHBondContact O-CD2 2.86Å
164L94.4Very high96.6Very high45 Ų4527.3 Ų27.324%0.23613%0.125CC..  trans-117.944-177.3-64.8179.2000110.7L159 N161 E162 D166 V167 K168L159-L164 HydrophobicContact CD2-CB 3.64Å; L159-L164 HydrophobicContact CD2-CD1 3.83Å; L159-L164 HydrophobicContact CD2-CG 4.39Å; N161-L164 HydrophobicContact CB-CB 4.37Å; N161-L164 HydrophobicContact CB-CD1 4.15Å; N161-L164 HydrophobicContact CB-CG 4.36Å; N161-L164 PolarHBondContact O-N 3.36Å; N161-L164 VanDerWaalsContact O-N 3.12Å; E162-L164 VanDerWaalsContact C-N 3.3Å; E162-L164 PolarHBondContact O-N 3.38Å; L164-D166 VanDerWaalsContact C-N 3.26Å; L164-D166 VanDerWaalsContact C-OD1 3.29Å; L164-D166 WeakPolarHBondContact CA-OD1 3.42Å; L164-D166 PolarHBondContact O-N 3.26Å; L164-V167 HydrophobicContact CB-CB 4.17Å; L164-V167 HydrophobicContact CB-CG2 4.06Å; L164-V167 HydrophobicContact CD2-CG2 4.44Å; L164-V167 WeakPolarHBondContact O-CB 3.33Å; L164-V167 PolarHBondContact O-N 3.16Å; L164-V167 VanDerWaalsContact O-N 3.08Å; L164-K168 PolarHBondContact O-N 2.83Å; L164-K168 VanDerWaalsContact O-N 3.14Å
165G95.9Very high96.6Very high0 Ų027.3 Ų27.30%013%0.125CC..Hα-helixtrans-66.5-26.3-179.800000113.5V167 K168 L169 R223 V226G165-V167 VanDerWaalsContact C-N 3.34Å; G165-K168 PolarHBondContact O-N 3.09Å; G165-L169 PolarHBondContact O-N 3.33Å; G165-R223 WeakPolarHBondContact CA-O 3.44Å; G165-R223 PolarHBondContact N-O 3.49Å; G165-V226 WeakPolarHBondContact O-CG1 3.36Å
166D95.3Very high96.6Very high26 Ų2627.3 Ų27.314%0.13913%0.125CC..Hα-helixtrans-58.3-44.8166.754.3-19.5000111.9L164 K168 L169 C170 R223 V237L164-D166 VanDerWaalsContact C-N 3.26Å; L164-D166 VanDerWaalsContact C-OD1 3.29Å; L164-D166 WeakPolarHBondContact CA-OD1 3.42Å; L164-D166 PolarHBondContact O-N 3.26Å; D166-K168 VanDerWaalsContact C-N 3.35Å; D166-K168 PolarHBondContact O-N 2.79Å; D166-L169 WeakPolarHBondContact O-CB 3.37Å; D166-L169 PolarHBondContact O-N 3.23Å; D166-C170 PolarHBondContact O-N 3.06Å; D166-C170 PolarHBondContact O-SG 3.26Å; D166-R223 HydrophobicContact CB-CB 3.89Å; D166-R223 WeakPolarHBondContact OD2-CD 3.35Å; D166-V237 HydrophobicContact CB-CG1 4.16Å; D166-V237 HydrophobicContact CB-CG2 4.18Å
167V95.8Very high96.5Very high13 Ų1327.4 Ų27.48%0.07913%0.125CC..Hα-helixtrans-64.2-41.2176.4-179.40000111L122 C124 L159 L164 G165 L169 C170 Q171L122-V167 HydrophobicContact CD2-CG1 4.16Å; C124-V167 VanDerWaalsContact SG-CG1 3.57Å; L159-V167 HydrophobicContact CD2-CB 4.09Å; L159-V167 HydrophobicContact CD2-CG1 3.93Å; L164-V167 HydrophobicContact CB-CB 4.17Å; L164-V167 HydrophobicContact CB-CG2 4.06Å; L164-V167 HydrophobicContact CD2-CG2 4.44Å; L164-V167 WeakPolarHBondContact O-CB 3.33Å; L164-V167 PolarHBondContact O-N 3.16Å; L164-V167 VanDerWaalsContact O-N 3.08Å; G165-V167 VanDerWaalsContact C-N 3.34Å; V167-L169 VanDerWaalsContact C-N 3.3Å; V167-L169 PolarHBondContact O-N 3.27Å; V167-C170 WeakPolarHBondContact O-CB 3.3Å; V167-C170 PolarHBondContact O-N 2.84Å; V167-Q171 VanDerWaalsContact O-CG 3.31Å; V167-Q171 WeakPolarHBondContact O-CG 3.37Å; V167-Q171 PolarHBondContact O-N 2.76Å
168K97.2Very high96.5Very high0 Ų028.6 Ų28.60%013%0.131CC..Hα-helixtrans-59.7-42.1173.7-57.2-175.7-156.9-161.40111.1L158 L159 F160 N161 L164 G165 D166 C170 Q171 V172 N200 L207L158-K168 HydrophobicContact CD1-CB 4.38Å; L159-K168 HydrophobicContact CB-CG 4.16Å; L159-K168 WeakPolarHBondContact O-CD 3.2Å; L159-K168 WeakPolarHBondContact O-CE 3.19Å; L159-K168 PolarHBondContact O-NZ 3.4Å; L159-K168 VanDerWaalsContact O-NZ 3.16Å; F160-K168 PolarHBondContact O-NZ 2.8Å; N161-K168 WeakPolarHBondContact O-CE 3.45Å; L164-K168 PolarHBondContact O-N 2.83Å; L164-K168 VanDerWaalsContact O-N 3.14Å; G165-K168 PolarHBondContact O-N 3.09Å; D166-K168 VanDerWaalsContact C-N 3.35Å; D166-K168 PolarHBondContact O-N 2.79Å; K168-C170 PolarHBondContact O-N 3.42Å; K168-Q171 WeakPolarHBondContact O-CB 3.35Å; K168-Q171 PolarHBondContact O-N 3.32Å; K168-V172 WeakPolarHBondContact O-CG2 3.5Å; K168-V172 PolarHBondContact O-N 2.72Å; K168-N200 HydrophobicContact CD-CB 4.44Å; K168-N200 WeakPolarHBondContact CD-O 3.16Å; K168-N200 PolarHBondContact NZ-O 3.21Å; K168-L207 HydrophobicContact CB-CD1 3.66Å
169L97.4Very high96.5Very high0 Ų028.6 Ų28.60%013%0.131CC..Hα-helixtrans-62.8-41.2176.4-17364.5000111.9G165 D166 V167 V172 A173 F210 L216 V226 L241 V276G165-L169 PolarHBondContact O-N 3.33Å; D166-L169 WeakPolarHBondContact O-CB 3.37Å; D166-L169 PolarHBondContact O-N 3.23Å; V167-L169 VanDerWaalsContact C-N 3.3Å; V167-L169 PolarHBondContact O-N 3.27Å; L169-V172 PolarHBondContact O-N 3.38Å; L169-A173 WeakPolarHBondContact O-CB 3.4Å; L169-A173 PolarHBondContact O-N 3.32Å; L169-F210 HydrophobicContact CD1-CB 4.21Å; L169-F210 HydrophobicContact CD1-CD1 3.4Å; L169-F210 VanDerWaalsContact CD1-CD1 3.4Å; L169-F210 HydrophobicContact CD1-CE1 3.96Å; L169-F210 HydrophobicContact CD1-CG 3.96Å; L169-L216 HydrophobicContact CD1-CD2 4.02Å; L169-L216 HydrophobicContact CD2-CD2 3.81Å; L169-V226 HydrophobicContact CB-CG1 4.05Å; L169-V226 HydrophobicContact CD2-CG1 4.43Å; L169-L241 HydrophobicContact CB-CD1 4.47Å; L169-L241 HydrophobicContact CD2-CD1 4.07Å; L169-L241 HydrophobicContact CD2-CD2 3.79Å; L169-L241 HydrophobicContact CG-CD1 4.41Å; L169-L241 HydrophobicContact CG-CD2 3.81Å; L169-V276 HydrophobicContact CD1-CG1 4.26Å; L169-V276 HydrophobicContact CD2-CG1 4.17Å; L169-V276 HydrophobicContact CG-CG1 4.39Å
170C96.8Very high96.4Very high5 Ų527.8 Ų27.83%0.03413%0.127CC..Hα-helixtrans-61.7-43.7172.7-61.80000112.4L122 D166 V167 K168 V172 A173 L174 L241 L242L122-C170 HydrophobicContact CD1-CB 4.28Å; L122-C170 HydrophobicContact CD2-CB 3.37Å; L122-C170 HydrophobicContact CG-CB 4.38Å; D166-C170 PolarHBondContact O-N 3.06Å; D166-C170 PolarHBondContact O-SG 3.26Å; V167-C170 WeakPolarHBondContact O-CB 3.3Å; V167-C170 PolarHBondContact O-N 2.84Å; K168-C170 PolarHBondContact O-N 3.42Å; C170-V172 VanDerWaalsContact C-N 3.32Å; C170-V172 PolarHBondContact O-N 2.81Å; C170-A173 PolarHBondContact O-N 3.27Å; C170-L174 WeakPolarHBondContact O-CG 3.29Å; C170-L174 PolarHBondContact O-N 2.83Å; C170-L241 WeakPolarHBondContact SG-CD1 3.31Å; C170-L241 VanDerWaalsContact SG-CG 3.52Å; C170-L241 PolarHBondContact SG-O 3.22Å; C170-L242 HydrophobicContact CB-CD2 4.13Å
171Q97.5Very high96.5Very high0 Ų023.6 Ų23.60%011%0.109CC..Hα-helixtrans-58.9-44.4177.5-70.3175.6-30.600111.3Y115 N126 L158 V167 K168 L174 L175Y115-Q171 HydrophobicContact CD1-CB 4.34Å; Y115-Q171 HydrophobicContact CD2-CB 3.79Å; Y115-Q171 HydrophobicContact CD2-CG 3.61Å; Y115-Q171 WeakPolarHBondContact CE1-O 3.5Å; Y115-Q171 HydrophobicContact CE2-CB 4.01Å; Y115-Q171 HydrophobicContact CE2-CG 4.3Å; Y115-Q171 HydrophobicContact CG-CB 4Å; Y115-Q171 HydrophobicContact CG-CG 3.77Å; N126-Q171 PolarHBondContact OD1-NE2 3.29Å; L158-Q171 HydrophobicContact CD2-CB 3.76Å; V167-Q171 VanDerWaalsContact O-CG 3.31Å; V167-Q171 WeakPolarHBondContact O-CG 3.37Å; V167-Q171 PolarHBondContact O-N 2.76Å; K168-Q171 WeakPolarHBondContact O-CB 3.35Å; K168-Q171 PolarHBondContact O-N 3.32Å; Q171-L174 PolarHBondContact O-N 3.1Å; Q171-L175 WeakPolarHBondContact O-CB 3.26Å; Q171-L175 PolarHBondContact O-N 3.1Å
172V98.2Very high96.6Very high1 Ų121.4 Ų21.41%0.00610%0.098CC..Hα-helixtrans-63-46.2174.4175.20000110.9L158 K168 L169 C170 L174 L175 L176 F199 L207 F210 L211L158-V172 HydrophobicContact CD1-CG2 3.47Å; L158-V172 VanDerWaalsContact CD1-CG2 3.47Å; L158-V172 HydrophobicContact CD2-CG2 4.28Å; K168-V172 WeakPolarHBondContact O-CG2 3.5Å; K168-V172 PolarHBondContact O-N 2.72Å; L169-V172 PolarHBondContact O-N 3.38Å; C170-V172 VanDerWaalsContact C-N 3.32Å; C170-V172 PolarHBondContact O-N 2.81Å; V172-L174 VanDerWaalsContact C-N 3.34Å; V172-L174 PolarHBondContact O-N 2.91Å; V172-L175 WeakPolarHBondContact O-CB 3.27Å; V172-L175 PolarHBondContact O-N 2.96Å; V172-L175 VanDerWaalsContact O-N 3.16Å; V172-L176 HydrophobicContact CG1-CD1 3.79Å; V172-L176 HydrophobicContact CG1-CG 4.09Å; V172-L176 WeakPolarHBondContact O-CB 3.42Å; V172-L176 VanDerWaalsContact O-CG 3.23Å; V172-L176 WeakPolarHBondContact O-CG 3.44Å; V172-L176 PolarHBondContact O-N 3.15Å; V172-F199 HydrophobicContact CG2-CD1 4.37Å; V172-F199 HydrophobicContact CG2-CE1 4.37Å; V172-L207 HydrophobicContact CG2-CD1 4.2Å; V172-L207 HydrophobicContact CG2-CD2 4.31Å; V172-L207 HydrophobicContact CG2-CG 4.43Å; V172-F210 HydrophobicContact CG1-CD1 4.14Å; V172-F210 HydrophobicContact CG1-CE1 3.86Å; V172-L211 HydrophobicContact CG1-CD2 3.67Å; V172-L211 HydrophobicContact CG1-CG 4.26Å
173A97.8Very high96.6Very high0 Ų016.8 Ų16.80%08%0.076CC..Hα-helixtrans-61.4-39.9179.900000112.7L169 C170 L176 A177 L242 V276L169-A173 WeakPolarHBondContact O-CB 3.4Å; L169-A173 PolarHBondContact O-N 3.32Å; C170-A173 PolarHBondContact O-N 3.27Å; A173-L176 PolarHBondContact O-N 3.21Å; A173-A177 PolarHBondContact O-N 2.6Å; A173-A177 VanDerWaalsContact O-N 3.16Å; A173-L242 HydrophobicContact CB-CD1 4.07Å; A173-L242 HydrophobicContact CB-CD2 4.11Å; A173-L242 HydrophobicContact CB-CG 4.35Å; A173-V276 HydrophobicContact CB-CG2 4.19Å
174L97.1Very high96.5Very high6 Ų611.1 Ų11.13%0.0316%0.06CC..Hα-helixtrans-61.8-48.3171.6-73.1179.5000111.7Y115 M117 L122 C170 Q171 V172 L176 A177 H178 L242 A246 I248Y115-L174 HydrophobicContact CD1-CB 4.12Å; Y115-L174 HydrophobicContact CD1-CD1 4.15Å; Y115-L174 HydrophobicContact CE1-CB 4.41Å; M117-L174 HydrophobicContact CE-CD2 4.26Å; L122-L174 HydrophobicContact CD1-CD1 3.76Å; C170-L174 WeakPolarHBondContact O-CG 3.29Å; C170-L174 PolarHBondContact O-N 2.83Å; Q171-L174 PolarHBondContact O-N 3.1Å; V172-L174 VanDerWaalsContact C-N 3.34Å; V172-L174 PolarHBondContact O-N 2.91Å; L174-L176 VanDerWaalsContact C-N 3.3Å; L174-L176 PolarHBondContact O-N 2.72Å; L174-A177 PolarHBondContact O-N 2.8Å; L174-H178 PolarHBondContact O-CD2 2.77Å; L174-H178 PolarHBondContact O-N 2.86Å; L174-L242 HydrophobicContact CD2-CD2 4.19Å; L174-L242 HydrophobicContact CG-CD2 4.15Å; L174-A246 HydrophobicContact CD2-CB 3.83Å; L174-I248 HydrophobicContact CD2-CD1 3.55Å
175L98.5Very high95.8Very high0 Ų011.9 Ų11.90%07%0.067CC..Hα-helixtrans-57.8-44.9177.5179.858.8000111.3V113 Y115 V130 T156 Q171 V172 A177 H178 L179 L195V113-L175 HydrophobicContact CG2-CD1 4.26Å; Y115-L175 HydrophobicContact CE1-CB 4.09Å; V130-L175 HydrophobicContact CG2-CD1 3.8Å; T156-L175 HydrophobicContact CG2-CD2 3.84Å; Q171-L175 WeakPolarHBondContact O-CB 3.26Å; Q171-L175 PolarHBondContact O-N 3.1Å; V172-L175 WeakPolarHBondContact O-CB 3.27Å; V172-L175 PolarHBondContact O-N 2.96Å; V172-L175 VanDerWaalsContact O-N 3.16Å; L175-A177 VanDerWaalsContact C-N 3.3Å; L175-A177 PolarHBondContact O-N 3.5Å; L175-H178 PolarHBondContact O-N 3.44Å; L175-L179 WeakPolarHBondContact O-CB 3.25Å; L175-L179 PolarHBondContact O-N 3.3Å; L175-L195 HydrophobicContact CD2-CD1 3.65Å
176L98.4Very high94.7Very high1 Ų115.6 Ų15.61%0.00511%0.105CC..Hα-helixtrans-62.1-35.9179.7-70.4173.5000112.3V172 A173 L174 L179 Q180 L195 F210 L211 C253 H278 L280 F282V172-L176 HydrophobicContact CG1-CD1 3.79Å; V172-L176 HydrophobicContact CG1-CG 4.09Å; V172-L176 WeakPolarHBondContact O-CB 3.42Å; V172-L176 VanDerWaalsContact O-CG 3.23Å; V172-L176 WeakPolarHBondContact O-CG 3.44Å; V172-L176 PolarHBondContact O-N 3.15Å; A173-L176 PolarHBondContact O-N 3.21Å; L174-L176 VanDerWaalsContact C-N 3.3Å; L174-L176 PolarHBondContact O-N 2.72Å; L176-L179 HydrophobicContact CD2-CD2 4.45Å; L176-L179 PolarHBondContact O-N 2.87Å; L176-Q180 VanDerWaalsContact O-CB 3.28Å; L176-Q180 WeakPolarHBondContact O-CB 3.31Å; L176-Q180 WeakPolarHBondContact O-CG 3.27Å; L176-Q180 PolarHBondContact O-N 2.78Å; L176-L195 HydrophobicContact CD2-CD2 4.48Å; L176-F210 HydrophobicContact CD1-CE1 3.61Å; L176-F210 HydrophobicContact CD1-CZ 3.63Å; L176-L211 HydrophobicContact CD1-CD2 4.3Å; L176-L211 HydrophobicContact CD2-CD2 4.32Å; L176-C253 HydrophobicContact CB-CB 3.81Å; L176-H278 HydrophobicContact CD1-CB 4.03Å; L176-H278 VanDerWaalsContact CD1-CD2 3.49Å; L176-H278 WeakPolarHBondContact CD1-CD2 3.48Å; L176-L280 HydrophobicContact CD2-CD1 4.21Å; L176-F282 HydrophobicContact CD2-CE2 3.61Å; L176-F282 HydrophobicContact CD2-CZ 4.12Å
177A97.6Very high93.4Very high1 Ų118.4 Ų18.41%0.00813%0.126CC..Hα-helixtrans-63.4-47.8174.300000113.1A173 L174 L175 Q181 I248 C253 F255A173-A177 PolarHBondContact O-N 2.6Å; A173-A177 VanDerWaalsContact O-N 3.16Å; L174-A177 PolarHBondContact O-N 2.8Å; L175-A177 VanDerWaalsContact C-N 3.3Å; L175-A177 PolarHBondContact O-N 3.5Å; A177-Q181 WeakPolarHBondContact O-CB 3.27Å; A177-Q181 PolarHBondContact O-N 3.03Å; A177-I248 HydrophobicContact CB-CD1 3.37Å; A177-I248 HydrophobicContact CB-CG1 3.61Å; A177-I248 HydrophobicContact CB-CG2 4.08Å; A177-C253 WeakPolarHBondContact CA-O 3.45Å; A177-C253 WeakPolarHBondContact CB-O 3.49Å; A177-C253 PolarHBondContact N-O 3.1Å; A177-F255 HydrophobicContact CB-CD2 4.29Å; A177-F255 HydrophobicContact CB-CE1 4.44Å; A177-F255 HydrophobicContact CB-CE2 3.87Å; A177-F255 HydrophobicContact CB-CZ 3.93Å
178H98Very high92.3Very high33 Ų3325.2 Ų25.215%0.15317%0.168CC..Hα-helixtrans-64.8-41.1174.9-75.6-77.2000112.3R111 V113 L174 L175 Q181 V182 F255R111-H178 HydrophobicContact CG-CB 4.16Å; V113-H178 VanDerWaalsContact CG1-CD2 3.42Å; V113-H178 WeakPolarHBondContact CG1-CD2 3.3Å; V113-H178 HydrophobicContact CG2-CB 3.52Å; L174-H178 PolarHBondContact O-CD2 2.77Å; L174-H178 PolarHBondContact O-N 2.86Å; L175-H178 PolarHBondContact O-N 3.44Å; H178-Q181 PolarHBondContact O-N 3.25Å; H178-V182 WeakPolarHBondContact O-CG2 3.31Å; H178-V182 PolarHBondContact O-N 2.93Å; H178-F255 AromaticContact CD2-CZ 3.81Å; H178-F255 AromaticContact CE1-CZ 3.53Å; H178-F255 AromaticContact CG-CZ 3.92Å; H178-F255 AromaticContact ND1-CZ 3.73Å; H178-F255 AromaticContact NE2-CZ 3.58Å
179L97.9Very high91.6Very high0 Ų026.8 Ų26.80%018%0.184CC..Hα-helixtrans-63.9-46.4-180-175.451000111.6V130 V152 A154 L175 L176 Q181 V182 A183 V193 L195 L280 F282V130-L179 HydrophobicContact CG1-CD1 3.77Å; V130-L179 HydrophobicContact CG2-CD1 4.43Å; V152-L179 HydrophobicContact CB-CD1 4.42Å; V152-L179 HydrophobicContact CG1-CD1 3.54Å; A154-L179 HydrophobicContact CB-CD1 3.9Å; A154-L179 HydrophobicContact CB-CD2 3.88Å; A154-L179 HydrophobicContact CB-CG 4.48Å; L175-L179 WeakPolarHBondContact O-CB 3.25Å; L175-L179 PolarHBondContact O-N 3.3Å; L176-L179 HydrophobicContact CD2-CD2 4.45Å; L176-L179 PolarHBondContact O-N 2.87Å; L179-Q181 VanDerWaalsContact C-N 3.33Å; L179-Q181 PolarHBondContact O-N 2.92Å; L179-V182 PolarHBondContact O-N 3.23Å; L179-A183 WeakPolarHBondContact O-CB 3.48Å; L179-A183 PolarHBondContact O-N 2.97Å; L179-V193 HydrophobicContact CD1-CG1 3.79Å; L179-V193 HydrophobicContact CD2-CG1 3.72Å; L179-V193 HydrophobicContact CG-CG1 3.94Å; L179-L195 HydrophobicContact CD2-CB 4.44Å; L179-L280 HydrophobicContact CD2-CD1 4.03Å; L179-L280 HydrophobicContact CG-CD1 4.04Å; L179-F282 HydrophobicContact CD2-CZ 4.16Å
180Q95.8Very high91.2Very high0 Ų028 Ų280%019%0.19CC..Hα-helixtrans-63.8-37.9175.8-72.6-176.9144.200111.7L176 A183 S184 F190 S252 C253 L280L176-Q180 VanDerWaalsContact O-CB 3.28Å; L176-Q180 WeakPolarHBondContact O-CB 3.31Å; L176-Q180 WeakPolarHBondContact O-CG 3.27Å; L176-Q180 PolarHBondContact O-N 2.78Å; Q180-A183 PolarHBondContact O-N 2.92Å; Q180-S184 VanDerWaalsContact O-CB 3.31Å; Q180-S184 WeakPolarHBondContact O-CB 3.25Å; Q180-S184 PolarHBondContact O-N 3.39Å; Q180-F190 HydrophobicContact CB-CD1 4.43Å; Q180-F190 HydrophobicContact CB-CE1 3.68Å; Q180-F190 HydrophobicContact CB-CZ 4.2Å; Q180-F190 HydrophobicContact CG-CE1 3.96Å; Q180-F190 HydrophobicContact CG-CZ 4.11Å; Q180-F190 WeakPolarHBondContact O-CE1 3.37Å; Q180-S252 PolarHBondContact NE2-O 2.83Å; Q180-C253 PolarHBondContact NE2-O 3.03Å; Q180-L280 HydrophobicContact CG-CD1 3.87Å; Q180-L280 HydrophobicContact CG-CD2 4.4Å; Q180-L280 HydrophobicContact CG-CG 3.85Å
181Q94.9Very high91Very high59 Ų5929.9 Ų29.928%0.27620%0.196SC..Hα-helixtrans-65.5-41.8175.6-170-179.866.100112A177 H178 L179 F255 D258A177-Q181 WeakPolarHBondContact O-CB 3.27Å; A177-Q181 PolarHBondContact O-N 3.03Å; H178-Q181 PolarHBondContact O-N 3.25Å; L179-Q181 VanDerWaalsContact C-N 3.33Å; L179-Q181 PolarHBondContact O-N 2.92Å; Q181-F255 HydrophobicContact CB-CD2 4.36Å; Q181-F255 HydrophobicContact CB-CE2 4.37Å; Q181-D258 WeakPolarHBondContact CG-OD2 3.37Å; Q181-D258 PolarHBondContact NE2-OD1 2.66Å; Q181-D258 VanDerWaalsContact NE2-OD1 3.09Å; Q181-D258 PolarHBondContact NE2-OD2 2.88Å; Q181-D258 VanDerWaalsContact NE2-OD2 3.16Å
182V96Very high90.9Very high10 Ų1030 Ų306%0.06120%0.197CC..Hα-helixtrans-70.1-39.6176.6174.50000111.4R111 V130 C132 V152 H178 L179 S184 R191R111-V182 HydrophobicContact CB-CG2 3.78Å; R111-V182 HydrophobicContact CG-CG2 4.22Å; V130-V182 HydrophobicContact CG1-CB 4.24Å; V130-V182 HydrophobicContact CG1-CG1 4.1Å; V130-V182 HydrophobicContact CG1-CG2 4.38Å; C132-V182 HydrophobicContact CB-CG1 3.99Å; V152-V182 HydrophobicContact CG1-CB 4.45Å; V152-V182 HydrophobicContact CG1-CG1 3.82Å; V152-V182 HydrophobicContact CG2-CG1 4.2Å; H178-V182 WeakPolarHBondContact O-CG2 3.31Å; H178-V182 PolarHBondContact O-N 2.93Å; L179-V182 PolarHBondContact O-N 3.23Å; V182-S184 VanDerWaalsContact C-N 3.33Å; V182-R191 PolarHBondContact O-NH1 3.42Å
183A94.7Very high90.9Very high0 Ų029.9 Ų29.90%020%0.196CC..Hα-helixtrans-76.4-18.9179.900000113.5V152 L179 Q180 T185 F190 R191 V193V152-A183 HydrophobicContact CB-CB 4.47Å; V152-A183 HydrophobicContact CG2-CB 4.01Å; L179-A183 WeakPolarHBondContact O-CB 3.48Å; L179-A183 PolarHBondContact O-N 2.97Å; Q180-A183 PolarHBondContact O-N 2.92Å; A183-T185 PolarHBondContact O-N 2.95Å; A183-F190 HydrophobicContact CB-CB 4.14Å; A183-F190 HydrophobicContact CB-CD1 4.08Å; A183-F190 WeakPolarHBondContact O-CA 3.46Å; A183-R191 WeakPolarHBondContact O-CG 3.37Å; A183-R191 PolarHBondContact O-N 2.87Å; A183-R191 PolarHBondContact O-NH1 3.16Å; A183-R191 VanDerWaalsContact O-NH1 3.16Å; A183-V193 HydrophobicContact CB-CG2 3.72Å
184S91.3Very high90.9Very high33 Ų3329.9 Ų29.923%0.23120%0.196CC..BIsolated β-bridgetrans-57.2125.3-179.6-179.80000112.1Q180 V182 G186 R191Q180-S184 VanDerWaalsContact O-CB 3.31Å; Q180-S184 WeakPolarHBondContact O-CB 3.25Å; Q180-S184 PolarHBondContact O-N 3.39Å; V182-S184 VanDerWaalsContact C-N 3.33Å; S184-G186 PolarHBondContact O-N 2.82Å; S184-G186 PolarHBondContact OG-N 2.87Å; S184-R191 VanDerWaalsContact C-NH1 3.26Å; S184-R191 PolarHBondContact O-NH1 3.1Å
185T79.3Confident91Very high61 Ų6129.6 Ų29.637%0.37420%0.195SC..  trans-80.60.5-179.459.30000113.6A183 S187 G189 R191A183-T185 PolarHBondContact O-N 2.95Å; T185-S187 PolarHBondContact O-N 2.83Å; T185-S187 PolarHBondContact OG1-N 3.2Å; T185-S187 PolarHBondContact OG1-OG 2.87Å; T185-S187 VanDerWaalsContact OG1-OG 3.11Å; T185-G189 PolarHBondContact N-O 3.31Å; T185-G189 PolarHBondContact OG1-O 3.23Å; T185-G189 VanDerWaalsContact OG1-O 3.1Å; T185-R191 HydrophobicContact CG2-CG 4.04Å
186G73.9Confident91Very high78 Ų7829.6 Ų29.680%0.80420%0.195SC*.SBendtrans78.9-15.7-169.900000113.9S184S184-G186 PolarHBondContact O-N 2.82Å; S184-G186 PolarHBondContact OG-N 2.87Å
187S68.3Low91Very high85 Ų8529.6 Ų29.659%0.59420%0.195SC*.SBendtrans-112.2-167.4170.968.90000110.8T185 G189T185-S187 PolarHBondContact O-N 2.83Å; T185-S187 PolarHBondContact OG1-N 3.2Å; T185-S187 PolarHBondContact OG1-OG 2.87Å; T185-S187 VanDerWaalsContact OG1-OG 3.11Å; S187-G189 PolarHBondContact O-N 2.97Å
188V71.7Confident91.1Very high156 Ų15629.6 Ų29.695%0.94520%0.195SC*.SBendtrans-71.1101.3177-178.40000109.8
189G82.7Confident91.1Very high34 Ų3428.1 Ų28.135%0.35119%0.188SC..SBendtrans137.1172.7169.400000114.7T185 S187T185-G189 PolarHBondContact N-O 3.31Å; T185-G189 PolarHBondContact OG1-O 3.23Å; T185-G189 VanDerWaalsContact OG1-O 3.1Å; S187-G189 PolarHBondContact O-N 2.97Å
190F89.7Confident91Very high26 Ų2629 Ų2911%0.11419%0.192CC..BIsolated β-bridgetrans-115.5148.1-178.5-58.4-75000110.5Q180 A183 Q279 L280 S316Q180-F190 HydrophobicContact CB-CD1 4.43Å; Q180-F190 HydrophobicContact CB-CE1 3.68Å; Q180-F190 HydrophobicContact CB-CZ 4.2Å; Q180-F190 HydrophobicContact CG-CE1 3.96Å; Q180-F190 HydrophobicContact CG-CZ 4.11Å; Q180-F190 WeakPolarHBondContact O-CE1 3.37Å; A183-F190 HydrophobicContact CB-CB 4.14Å; A183-F190 HydrophobicContact CB-CD1 4.08Å; A183-F190 WeakPolarHBondContact O-CA 3.46Å; F190-Q279 HydrophobicContact CE2-CB 3.64Å; F190-Q279 HydrophobicContact CZ-CB 4.1Å; F190-L280 HydrophobicContact CB-CD2 3.93Å; F190-L280 HydrophobicContact CD1-CD2 4.24Å; F190-L280 HydrophobicContact CD2-CD2 3.86Å; F190-L280 HydrophobicContact CE2-CD2 4.48Å; F190-L280 HydrophobicContact CG-CD2 3.72Å; F190-S316 WeakPolarHBondContact O-CB 3.26Å; F190-S316 PolarHBondContact O-OG 3.43Å
191R92.5Very high91Very high43 Ų4329 Ų2916%0.16219%0.193CC..  trans-58.1160.2161.2-67.1171.6-176.783.2-3.8110.5E150 V152 V182 A183 S184 T185 V193E150-R191 IonicContact OE2-CZ 2.74Å; E150-R191 IonicContact OE2-NE 2.78Å; E150-R191 PolarHBondContact OE2-NE 2.76Å; E150-R191 IonicContact OE2-NH2 3.55Å; E150-R191 PolarHBondContact OE2-NH2 2.83Å; V152-R191 HydrophobicContact CG2-CB 4.23Å; V182-R191 PolarHBondContact O-NH1 3.42Å; A183-R191 WeakPolarHBondContact O-CG 3.37Å; A183-R191 PolarHBondContact O-N 2.87Å; A183-R191 PolarHBondContact O-NH1 3.16Å; A183-R191 VanDerWaalsContact O-NH1 3.16Å; S184-R191 VanDerWaalsContact C-NH1 3.26Å; S184-R191 PolarHBondContact O-NH1 3.1Å; T185-R191 HydrophobicContact CG2-CG 4.04Å; R191-V193 WeakPolarHBondContact O-CG2 3.47Å; R191-V193 PolarHBondContact O-N 3.2Å
192P95Very high91Very high2 Ų228.3 Ų28.31%0.01319%0.193CC..  trans-55.2139.4168.4-24.535000111.3I151 V152 S314 K333 L334 F373I151-P192 HydrophobicContact CG1-CB 4.31Å; V152-P192 PolarHBondContact N-O 2.96Å; P192-S314 WeakPolarHBondContact CA-O 3.1Å; P192-K333 HydrophobicContact CG-CB 3.56Å; P192-K333 HydrophobicContact CG-CD 4.23Å; P192-L334 HydrophobicContact CB-CB 3.7Å; P192-L334 HydrophobicContact CB-CD2 3.93Å; P192-L334 HydrophobicContact CB-CG 4.4Å; P192-L334 HydrophobicContact CG-CB 4.25Å; P192-F373 HydrophobicContact CG-CE2 3.92Å
193V97.6Very high90.6Very high0 Ų029 Ų290%020%0.199CC..EExtended strand (participates in β ladder)trans-125.7138.2-178.6178.70000109.5V152 L179 A183 R191 L280 F282 Y313 S314V152-V193 HydrophobicContact CB-CG2 4.33Å; V152-V193 CarbonylContact O-C 3.53Å; V152-V193 VanDerWaalsContact O-CA 3.24Å; V152-V193 WeakPolarHBondContact O-CA 3.08Å; L179-V193 HydrophobicContact CD1-CG1 3.79Å; L179-V193 HydrophobicContact CD2-CG1 3.72Å; L179-V193 HydrophobicContact CG-CG1 3.94Å; A183-V193 HydrophobicContact CB-CG2 3.72Å; R191-V193 WeakPolarHBondContact O-CG2 3.47Å; R191-V193 PolarHBondContact O-N 3.2Å; V193-L280 HydrophobicContact CG2-CD2 3.97Å; V193-F282 HydrophobicContact CB-CE1 4.49Å; V193-F282 HydrophobicContact CG1-CE1 3.99Å; V193-F282 HydrophobicContact CG1-CZ 4.29Å; V193-Y313 CarbonylContact O-C 3.47Å; V193-Y313 WeakPolarHBondContact O-CA 3.46Å; V193-S314 PolarHBondContact N-O 2.9Å; V193-S314 PolarHBondContact O-N 3.34Å
194I98.7Very high90.2Very high0 Ų031.9 Ų31.90%022%0.219CC..EExtended strand (participates in β ladder)trans-116129.1160.2-59.6171.2000107.4F9 L11 I151 V152 V153 A154 M311 F312 L334 F371F9-I194 HydrophobicContact CE2-CD1 4Å; F9-I194 HydrophobicContact CZ-CD1 3.91Å; L11-I194 HydrophobicContact CD1-CB 4.31Å; L11-I194 HydrophobicContact CD1-CD1 3.99Å; L11-I194 HydrophobicContact CD1-CG2 3.92Å; L11-I194 HydrophobicContact CD2-CG2 4.35Å; I151-I194 HydrophobicContact CD1-CD1 3.71Å; I151-I194 HydrophobicContact CD1-CG1 4.07Å; V152-I194 PolarHBondContact O-N 2.93Å; V153-I194 CarbonylContact C-O 3.59Å; V153-I194 WeakPolarHBondContact CA-O 3.48Å; A154-I194 PolarHBondContact N-O 2.84Å; I194-M311 HydrophobicContact CG2-CG 4.16Å; I194-F312 CarbonylContact C-O 3.45Å; I194-F312 WeakPolarHBondContact CA-O 3.27Å; I194-L334 HydrophobicContact CD1-CD2 4.17Å; I194-L334 HydrophobicContact CG1-CD2 3.77Å; I194-F371 HydrophobicContact CD1-CD1 4.18Å; I194-F371 HydrophobicContact CD1-CD2 3.94Å; I194-F371 HydrophobicContact CD1-CE1 4.07Å; I194-F371 HydrophobicContact CD1-CE2 3.82Å; I194-F371 HydrophobicContact CD1-CG 4.12Å; I194-F371 HydrophobicContact CD1-CZ 3.87Å; I194-F371 HydrophobicContact CG1-CE1 4.37Å; I194-F371 HydrophobicContact CG1-CZ 4.34Å
195L98.8Very high90.4Very high0 Ų030.4 Ų30.40%021%0.209CC..EExtended strand (participates in β ladder)trans-120.2123.7176.7168.162.2000108A154 L175 L176 L179 F199 L211 F282 F312A154-L195 HydrophobicContact CB-CD1 3.68Å; L175-L195 HydrophobicContact CD2-CD1 3.65Å; L176-L195 HydrophobicContact CD2-CD2 4.48Å; L179-L195 HydrophobicContact CD2-CB 4.44Å; L195-F199 HydrophobicContact CD1-CZ 4.05Å; L195-F199 HydrophobicContact CD2-CE1 4.45Å; L195-F199 HydrophobicContact CD2-CZ 4.13Å; L195-F199 HydrophobicContact CG-CZ 3.87Å; L195-L211 HydrophobicContact CD2-CD2 3.86Å; L195-F282 HydrophobicContact CB-CE1 3.71Å; L195-F282 HydrophobicContact CB-CZ 3.91Å; L195-F282 HydrophobicContact CD2-CE1 4.26Å; L195-F282 HydrophobicContact CD2-CE2 4.03Å; L195-F282 HydrophobicContact CD2-CZ 3.73Å; L195-F282 HydrophobicContact CG-CZ 4.48Å; L195-F312 PolarHBondContact N-O 2.97Å; L195-F312 PolarHBondContact O-N 2.85Å
196C98.8Very high91.2Very high0 Ų028.3 Ų28.30%020%0.196CC..EExtended strand (participates in β ladder)trans-148.6168.4-178.264.40000113C59 A154 N155 T156 H310 M311C59-C196 WeakPolarHBondContact CB-SG 3.21Å; A154-C196 PolarHBondContact O-N 3.4Å; N155-C196 WeakPolarHBondContact CA-O 3.24Å; T156-C196 PolarHBondContact N-O 2.83Å; T156-C196 VanDerWaalsContact N-O 3.15Å; C196-H310 WeakPolarHBondContact CA-O 3.48Å; C196-M311 HydrophobicContact CB-CB 4.11Å; C196-M311 HydrophobicContact CB-CG 3.95Å
197G98.6Very high92.3Very high0 Ų024.6 Ų24.60%016%0.158CC..EExtended strand (participates in β ladder)trans139.5-163.6172.500000112.6S13 T156 F199 D309 H310S13-G197 WeakPolarHBondContact OG-CA 3.19Å; S13-G197 PolarHBondContact OG-N 3.48Å; T156-G197 VanDerWaalsContact O-CA 3.3Å; T156-G197 WeakPolarHBondContact O-CA 3.44Å; G197-F199 VanDerWaalsContact O-CD2 3.32Å; G197-F199 WeakPolarHBondContact O-CD2 3.48Å; G197-D309 WeakPolarHBondContact O-CA 3.19Å; G197-H310 PolarHBondContact N-O 3.07Å; G197-H310 VanDerWaalsContact N-O 3.1Å; G197-H310 PolarHBondContact O-N 2.91Å
198D98.4Very high93.7Very high2 Ų221 Ų211%0.01113%0.132CC..EExtended strand (participates in β ladder)trans-91105176.5-174.9-16.8000109.2N15 Q61 T156 H157 L158 N200 D309 H364N15-D198 PolarHBondContact ND2-OD2 3.2Å; Q61-D198 HydrophobicContact CG-CB 4.41Å; T156-D198 PolarHBondContact O-N 3.47Å; T156-D198 VanDerWaalsContact O-N 3.15Å; H157-D198 CarbonylContact C-O 3.58Å; H157-D198 WeakPolarHBondContact CA-O 3.31Å; H157-D198 IonicContact CD2-OD2 3.84Å; H157-D198 IonicContact NE2-OD2 3.11Å; L158-D198 PolarHBondContact N-O 3.44Å; D198-N200 VanDerWaalsContact C-N 3.33Å; D198-N200 PolarHBondContact OD1-N 3.19Å; D198-N200 PolarHBondContact OD1-ND2 2.8Å; D198-D309 WeakPolarHBondContact CB-OD1 3.38Å; D198-H364 IonicContact OD2-CE1 3.77Å; D198-H364 PolarHBondContact OD2-CE1 3.31Å; D198-H364 IonicContact OD2-NE2 2.7Å
199F98.1Very high94.8Very high1 Ų119 Ų190%0.00411%0.107CC..  trans-85.7-10.5-178.8-74.3-108.1000112.2T156 L158 V172 L195 G197 A201 L207 L211 V308 H310 F312T156-F199 HydrophobicContact CG2-CE2 4.43Å; T156-F199 HydrophobicContact CG2-CZ 4.19Å; L158-F199 WeakPolarHBondContact CB-O 3.33Å; L158-F199 HydrophobicContact CD1-CB 4.03Å; L158-F199 HydrophobicContact CD1-CD1 3.66Å; L158-F199 HydrophobicContact CD1-CE1 4.45Å; L158-F199 HydrophobicContact CD1-CG 4.14Å; L158-F199 WeakPolarHBondContact CD1-O 3.44Å; L158-F199 HydrophobicContact CG-CD1 4.44Å; V172-F199 HydrophobicContact CG2-CD1 4.37Å; V172-F199 HydrophobicContact CG2-CE1 4.37Å; L195-F199 HydrophobicContact CD1-CZ 4.05Å; L195-F199 HydrophobicContact CD2-CE1 4.45Å; L195-F199 HydrophobicContact CD2-CZ 4.13Å; L195-F199 HydrophobicContact CG-CZ 3.87Å; G197-F199 VanDerWaalsContact O-CD2 3.32Å; G197-F199 WeakPolarHBondContact O-CD2 3.48Å; F199-A201 HydrophobicContact CB-CB 4.18Å; F199-A201 PolarHBondContact O-N 2.84Å; F199-L207 HydrophobicContact CD1-CD2 3.96Å; F199-L211 HydrophobicContact CD1-CD1 4.02Å; F199-L211 HydrophobicContact CE1-CD1 3.6Å; F199-L211 HydrophobicContact CZ-CD1 4.41Å; F199-V308 PolarHBondContact N-O 3.11Å; F199-H310 HydrophobicContact CD2-CB 3.81Å; F199-H310 HydrophobicContact CE2-CB 4.09Å; F199-H310 HydrophobicContact CG-CB 4.46Å; F199-F312 HydrophobicContact CE1-CE2 4.41Å; F199-F312 HydrophobicContact CE2-CE2 4.35Å; F199-F312 HydrophobicContact CZ-CD2 4.37Å; F199-F312 HydrophobicContact CZ-CE2 4.16Å
200N96.9Very high95.5Very high19 Ų1917.3 Ų17.310%0.1029%0.09CC..SBendtrans43.153.4-168.2-75-90000109.7H157 L158 L159 K168 D198 Q229 V308H157-N200 PolarHBondContact CD2-ND2 3.1Å; H157-N200 PolarHBondContact NE2-ND2 3.25Å; L158-N200 PolarHBondContact O-ND2 3.47Å; L159-N200 WeakPolarHBondContact O-CB 3.3Å; K168-N200 HydrophobicContact CD-CB 4.44Å; K168-N200 WeakPolarHBondContact CD-O 3.16Å; K168-N200 PolarHBondContact NZ-O 3.21Å; D198-N200 VanDerWaalsContact C-N 3.33Å; D198-N200 PolarHBondContact OD1-N 3.19Å; D198-N200 PolarHBondContact OD1-ND2 2.8Å; N200-Q229 PolarHBondContact O-OE1 2.79Å; N200-V308 PolarHBondContact N-O 3.45Å
201A96.2Very high95.9Very high1 Ų116.1 Ų16.11%0.0089%0.085CC..  trans-151138.5-179.500000109.4F199 L207 S227 V308 H310F199-A201 HydrophobicContact CB-CB 4.18Å; F199-A201 PolarHBondContact O-N 2.84Å; A201-L207 HydrophobicContact CB-CD2 4.01Å; A201-S227 CarbonylContact C-O 3.51Å; A201-S227 WeakPolarHBondContact CA-O 3.41Å; A201-V308 WeakPolarHBondContact O-CA 3.38Å; A201-H310 PolarHBondContact O-NE2 2.88Å
202T93.8Very high96Very high44 Ų4415.4 Ų15.427%0.279%0.086SC..  trans-74157.6179.759.60000111.9S205 S227 G228 Q229 W307T202-S205 VanDerWaalsContact O-CB 3.31Å; T202-S205 WeakPolarHBondContact O-CB 3.35Å; T202-S205 PolarHBondContact O-N 2.99Å; T202-S205 PolarHBondContact O-OG 3.48Å; T202-S227 PolarHBondContact N-O 3.47Å; T202-S227 PolarHBondContact OG1-O 3.22Å; T202-G228 WeakPolarHBondContact OG1-CA 3.36Å; T202-G228 PolarHBondContact OG1-O 3.2Å; T202-Q229 HydrophobicContact CG2-CG 4.01Å; T202-W307 WeakPolarHBondContact CA-O 3.47Å
203A87Confident96.1Very high24 Ų2421.4 Ų21.420%0.19811%0.111CC..THydrogen-bonded Turntrans-57.3140.7163.900000109.4S205 W307A203-S205 PolarHBondContact O-N 3.02Å; A203-W307 HydrophobicContact CB-CD2 4.43Å
204S87Confident96Very high61 Ų6121.9 Ų21.943%0.42712%0.116SC..THydrogen-bonded Turntrans6616-175.4-47.30000116.1W209S204-W209 WeakPolarHBondContact O-CZ2 3.24Å
205S94.6Very high95.8Very high2 Ų227.7 Ų27.71%0.01414%0.142CC..  trans-72157.9168.560.80000112.1T202 A203 L207 Y208 W209 S227T202-S205 VanDerWaalsContact O-CB 3.31Å; T202-S205 WeakPolarHBondContact O-CB 3.35Å; T202-S205 PolarHBondContact O-N 2.99Å; T202-S205 PolarHBondContact O-OG 3.48Å; A203-S205 PolarHBondContact O-N 3.02Å; S205-L207 PolarHBondContact O-N 3.44Å; S205-Y208 WeakPolarHBondContact O-CA 3.19Å; S205-Y208 WeakPolarHBondContact O-CB 3.33Å; S205-Y208 PolarHBondContact O-N 3.26Å; S205-Y208 WeakPolarHBondContact OG-CB 3.36Å; S205-Y208 PolarHBondContact OG-N 3.46Å; S205-W209 PolarHBondContact O-N 2.8Å; S205-S227 WeakPolarHBondContact CB-O 3.46Å
206P97Very high95.8Very high16 Ų1628.6 Ų28.610%0.10415%0.146CC..Hα-helixtrans-52.6-37.2170.6-27.834.1000113.8W209 F210 L216 L221 E225 V226P206-W209 HydrophobicContact CB-CE3 4.48Å; P206-W209 HydrophobicContact CG-CE3 4.49Å; P206-W209 HydrophobicContact CG-CZ3 4.4Å; P206-W209 PolarHBondContact O-N 3.1Å; P206-F210 PolarHBondContact O-N 2.7Å; P206-L216 HydrophobicContact CB-CD1 4.14Å; P206-L216 HydrophobicContact CB-CD2 4.28Å; P206-L221 HydrophobicContact CB-CD1 4.3Å; P206-L221 HydrophobicContact CB-CD2 3.92Å; P206-L221 HydrophobicContact CG-CD1 3.95Å; P206-L221 HydrophobicContact CG-CD2 4.45Å; P206-E225 VanDerWaalsContact CD-O 3.31Å; P206-E225 WeakPolarHBondContact CD-O 3.29Å; P206-V226 WeakPolarHBondContact CD-O 3.44Å
207L97.4Very high95.6Very high1 Ų134.3 Ų34.31%0.00517%0.171CC..Hα-helixtrans-64.1-41.8174.4-173.8149000111.8L158 K168 V172 F199 A201 S205 F210 L211 V226L158-L207 HydrophobicContact CD1-CD1 4.35Å; K168-L207 HydrophobicContact CB-CD1 3.66Å; V172-L207 HydrophobicContact CG2-CD1 4.2Å; V172-L207 HydrophobicContact CG2-CD2 4.31Å; V172-L207 HydrophobicContact CG2-CG 4.43Å; F199-L207 HydrophobicContact CD1-CD2 3.96Å; A201-L207 HydrophobicContact CB-CD2 4.01Å; S205-L207 PolarHBondContact O-N 3.44Å; L207-F210 WeakPolarHBondContact O-CB 3.4Å; L207-F210 PolarHBondContact O-N 2.7Å; L207-L211 HydrophobicContact CD2-CD1 4.19Å; L207-L211 PolarHBondContact O-N 3.09Å; L207-V226 HydrophobicContact CB-CG1 4.2Å; L207-V226 VanDerWaalsContact CB-O 3.3Å; L207-V226 WeakPolarHBondContact CB-O 3.46Å; L207-V226 PolarHBondContact N-O 3.39Å
208Y96.2Very high95.5Very high9 Ų934.3 Ų34.34%0.03517%0.171CC..Hα-helixtrans-63-42.2173.5179.5-82.1000111.8S205 F210 L211 T212 P284 H310 F312S205-Y208 WeakPolarHBondContact O-CA 3.19Å; S205-Y208 WeakPolarHBondContact O-CB 3.33Å; S205-Y208 PolarHBondContact O-N 3.26Å; S205-Y208 WeakPolarHBondContact OG-CB 3.36Å; S205-Y208 PolarHBondContact OG-N 3.46Å; Y208-F210 VanDerWaalsContact C-N 3.34Å; Y208-F210 PolarHBondContact O-N 2.95Å; Y208-L211 PolarHBondContact O-N 2.92Å; Y208-T212 HydrophobicContact CD1-CG2 4.16Å; Y208-T212 HydrophobicContact CE1-CG2 3.7Å; Y208-T212 PolarHBondContact O-N 3.22Å; Y208-T212 PolarHBondContact O-OG1 2.95Å; Y208-P284 HydrophobicContact CE2-CB 4.46Å; Y208-P284 WeakPolarHBondContact OH-CB 3.39Å; Y208-P284 VanDerWaalsContact OH-CG 3.31Å; Y208-P284 WeakPolarHBondContact OH-CG 3.18Å; Y208-H310 AromaticContact CD2-CE1 3.8Å; Y208-H310 AromaticContact CD2-ND1 3.69Å; Y208-H310 AromaticContact CE2-ND1 3.71Å; Y208-F312 AromaticContact CD2-CE1 3.96Å; Y208-F312 HydrophobicContact CD2-CE1 3.96Å; Y208-F312 AromaticContact CD2-CZ 3.72Å; Y208-F312 HydrophobicContact CD2-CZ 3.72Å; Y208-F312 AromaticContact CE2-CE1 3.65Å; Y208-F312 HydrophobicContact CE2-CE1 3.65Å; Y208-F312 AromaticContact CE2-CZ 3.79Å; Y208-F312 HydrophobicContact CE2-CZ 3.79Å
209W95.8Very high95.2Very high113 Ų11340.8 Ų40.843%0.42820%0.201SC..Hα-helixtrans-66.7-34.8176.5-61.5-27.8000112.9S204 S205 P206 L211 T212 K213S204-W209 WeakPolarHBondContact O-CZ2 3.24Å; S205-W209 PolarHBondContact O-N 2.8Å; P206-W209 HydrophobicContact CB-CE3 4.48Å; P206-W209 HydrophobicContact CG-CE3 4.49Å; P206-W209 HydrophobicContact CG-CZ3 4.4Å; P206-W209 PolarHBondContact O-N 3.1Å; W209-L211 VanDerWaalsContact C-N 3.31Å; W209-L211 PolarHBondContact O-N 3.06Å; W209-T212 WeakPolarHBondContact CA-OG1 3.38Å; W209-T212 PolarHBondContact O-N 2.74Å; W209-K213 HydrophobicContact CB-CG 4.38Å; W209-K213 WeakPolarHBondContact O-CA 3.3Å; W209-K213 VanDerWaalsContact O-CB 3.24Å; W209-K213 WeakPolarHBondContact O-CB 3.31Å; W209-K213 WeakPolarHBondContact O-CG 3.44Å; W209-K213 PolarHBondContact O-N 3.38Å
210F97.8Very high94.9Very high0 Ų044.1 Ų44.10%023%0.229CC..Hα-helixtrans-55.8-49.7172.9170.3-132.6000111L169 V172 L176 P206 L207 Y208 G214 L216 V276 H278L169-F210 HydrophobicContact CD1-CB 4.21Å; L169-F210 HydrophobicContact CD1-CD1 3.4Å; L169-F210 VanDerWaalsContact CD1-CD1 3.4Å; L169-F210 HydrophobicContact CD1-CE1 3.96Å; L169-F210 HydrophobicContact CD1-CG 3.96Å; V172-F210 HydrophobicContact CG1-CD1 4.14Å; V172-F210 HydrophobicContact CG1-CE1 3.86Å; L176-F210 HydrophobicContact CD1-CE1 3.61Å; L176-F210 HydrophobicContact CD1-CZ 3.63Å; P206-F210 PolarHBondContact O-N 2.7Å; L207-F210 WeakPolarHBondContact O-CB 3.4Å; L207-F210 PolarHBondContact O-N 2.7Å; Y208-F210 VanDerWaalsContact C-N 3.34Å; Y208-F210 PolarHBondContact O-N 2.95Å; F210-G214 VanDerWaalsContact O-CA 3.25Å; F210-G214 WeakPolarHBondContact O-CA 3.35Å; F210-G214 PolarHBondContact O-N 3.45Å; F210-L216 HydrophobicContact CB-CB 3.79Å; F210-L216 HydrophobicContact CB-CD2 4.07Å; F210-L216 HydrophobicContact CD2-CB 4.02Å; F210-L216 HydrophobicContact CG-CB 4.19Å; F210-V276 HydrophobicContact CD2-CG1 3.88Å; F210-V276 HydrophobicContact CE1-CG1 4.38Å; F210-V276 HydrophobicContact CE1-CG2 4.37Å; F210-V276 HydrophobicContact CE2-CB 4.24Å; F210-V276 HydrophobicContact CE2-CG1 3.73Å; F210-V276 HydrophobicContact CE2-CG2 3.91Å; F210-V276 HydrophobicContact CG-CG1 4.29Å; F210-V276 HydrophobicContact CZ-CB 4.37Å; F210-V276 HydrophobicContact CZ-CG1 3.99Å; F210-V276 HydrophobicContact CZ-CG2 3.63Å; F210-H278 AromaticContact CE2-CD2 3.62Å; F210-H278 AromaticContact CZ-CD2 3.75Å; F210-H278 PolarHBondContact O-NE2 3.49Å; F210-H278 VanDerWaalsContact O-NE2 3.15Å
211L97.4Very high94.9Very high1 Ų144.4 Ų44.41%0.00523%0.231CC..Hα-helixtrans-63.2-45.4179.3-71.8167.9000112.4V172 L176 L195 F199 L207 Y208 W209 H278 F282 F312V172-L211 HydrophobicContact CG1-CD2 3.67Å; V172-L211 HydrophobicContact CG1-CG 4.26Å; L176-L211 HydrophobicContact CD1-CD2 4.3Å; L176-L211 HydrophobicContact CD2-CD2 4.32Å; L195-L211 HydrophobicContact CD2-CD2 3.86Å; F199-L211 HydrophobicContact CD1-CD1 4.02Å; F199-L211 HydrophobicContact CE1-CD1 3.6Å; F199-L211 HydrophobicContact CZ-CD1 4.41Å; L207-L211 HydrophobicContact CD2-CD1 4.19Å; L207-L211 PolarHBondContact O-N 3.09Å; Y208-L211 PolarHBondContact O-N 2.92Å; W209-L211 VanDerWaalsContact C-N 3.31Å; W209-L211 PolarHBondContact O-N 3.06Å; L211-H278 WeakPolarHBondContact CA-NE2 3.36Å; L211-H278 PolarHBondContact O-CE1 2.92Å; L211-H278 PolarHBondContact O-NE2 3.06Å; L211-H278 VanDerWaalsContact O-NE2 3.14Å; L211-F282 HydrophobicContact CD2-CD2 4.24Å; L211-F282 HydrophobicContact CD2-CE2 4.23Å; L211-F282 WeakPolarHBondContact O-CB 3.25Å; L211-F312 HydrophobicContact CB-CZ 4.44Å; L211-F312 HydrophobicContact CD1-CD2 4.22Å; L211-F312 HydrophobicContact CD1-CE2 3.6Å; L211-F312 HydrophobicContact CD1-CZ 3.91Å
212T95.6Very high94.9Very high28 Ų2845.6 Ų45.617%0.17224%0.238CC..Hα-helixtrans-83.3-35.2-172.652.80000114Y208 W209 P284 F312Y208-T212 HydrophobicContact CD1-CG2 4.16Å; Y208-T212 HydrophobicContact CE1-CG2 3.7Å; Y208-T212 PolarHBondContact O-N 3.22Å; Y208-T212 PolarHBondContact O-OG1 2.95Å; W209-T212 WeakPolarHBondContact CA-OG1 3.38Å; W209-T212 PolarHBondContact O-N 2.74Å; T212-P284 HydrophobicContact CG2-CG 4.36Å; T212-F312 HydrophobicContact CG2-CD1 4.11Å; T212-F312 HydrophobicContact CG2-CE1 3.74Å
213K95.5Very high95Very high128 Ų12846.9 Ų46.956%0.55724%0.238SC*.Hα-helixtrans-93.6-11.5179.7-48.2-59.2-180-168.40112.2W209 K215 E289W209-K213 HydrophobicContact CB-CG 4.38Å; W209-K213 WeakPolarHBondContact O-CA 3.3Å; W209-K213 VanDerWaalsContact O-CB 3.24Å; W209-K213 WeakPolarHBondContact O-CB 3.31Å; W209-K213 WeakPolarHBondContact O-CG 3.44Å; W209-K213 PolarHBondContact O-N 3.38Å; K213-K215 PolarHBondContact O-N 3.32Å; K213-E289 IonicContact NZ-OE1 2.7Å; K213-E289 PolarHBondContact NZ-OE1 3.47Å
214G95.8Very high95.4Very high10 Ų1046.8 Ų46.810%0.10323%0.233CC..SBendtrans76.3-2175.600000115.3F210 G277 H278F210-G214 VanDerWaalsContact O-CA 3.25Å; F210-G214 WeakPolarHBondContact O-CA 3.35Å; F210-G214 PolarHBondContact O-N 3.45Å; G214-G277 CarbonylContact O-C 3.54Å; G214-G277 WeakPolarHBondContact O-CA 3.43Å; G214-H278 PolarHBondContact O-N 3.47Å
215K96.1Very high95.9Very high122 Ų12246.6 Ų46.653%0.5323%0.226SC..EExtended strand (participates in β ladder)trans-148.4142.1177.7-66.4-172.9-178.9-177.40110.6K213 V276K213-K215 PolarHBondContact O-N 3.32Å; K215-V276 CarbonylContact C-O 3.53Å; K215-V276 WeakPolarHBondContact CA-O 3.42Å
216L97.1Very high96Very high18 Ų1846.5 Ų46.59%0.09423%0.225CC..EExtended strand (participates in β ladder)trans-138.8120.2173.2176.468.4000110.2L169 P206 F210 L221 Y275 V276L169-L216 HydrophobicContact CD1-CD2 4.02Å; L169-L216 HydrophobicContact CD2-CD2 3.81Å; P206-L216 HydrophobicContact CB-CD1 4.14Å; P206-L216 HydrophobicContact CB-CD2 4.28Å; F210-L216 HydrophobicContact CB-CB 3.79Å; F210-L216 HydrophobicContact CB-CD2 4.07Å; F210-L216 HydrophobicContact CD2-CB 4.02Å; F210-L216 HydrophobicContact CG-CB 4.19Å; L216-L221 HydrophobicContact CD1-CD2 4.43Å; L216-L221 HydrophobicContact CD2-CD2 4.07Å; L216-L221 HydrophobicContact CG-CD2 4.5Å; L216-Y275 CarbonylContact O-C 3.52Å; L216-Y275 WeakPolarHBondContact O-CA 3.16Å; L216-Y275 WeakPolarHBondContact O-CB 3.42Å; L216-V276 HydrophobicContact CB-CG1 4.08Å; L216-V276 PolarHBondContact N-O 2.89Å; L216-V276 PolarHBondContact O-N 2.89Å
217F96.1Very high96Very high120 Ų12045.8 Ų45.853%0.52622%0.22SC..EExtended strand (participates in β ladder)trans-83.5128.9168.2-64.9-89.3000108.9Q273 Y275F217-Q273 HydrophobicContact CE1-CB 4.41Å; F217-Y275 HydrophobicContact CD1-CD1 4.32Å; F217-Y275 HydrophobicContact CD1-CG 4.29Å; F217-Y275 AromaticContact CE1-CD1 3.78Å; F217-Y275 HydrophobicContact CE1-CD1 3.78Å; F217-Y275 HydrophobicContact CE1-CG 4.02Å; F217-Y275 HydrophobicContact CZ-CD1 4.41Å; F217-Y275 HydrophobicContact CZ-CG 4.5Å
218Y95.3Very high95.9Very high1 Ų147.4 Ų47.40%0.00424%0.238CC..  trans-127.87.5-172.259.8-99.5000114.9A220 L221 V237 G238 Y239 L241 E250 A274 Y275 V276Y218-A220 VanDerWaalsContact C-N 3.26Å; Y218-A220 PolarHBondContact O-N 3.39Å; Y218-A220 VanDerWaalsContact O-N 3.16Å; Y218-L221 WeakPolarHBondContact O-CB 3.37Å; Y218-L221 PolarHBondContact O-N 2.92Å; Y218-V237 HydrophobicContact CD2-CB 3.97Å; Y218-V237 HydrophobicContact CD2-CG1 3.5Å; Y218-V237 HydrophobicContact CE2-CG1 4.08Å; Y218-V237 HydrophobicContact CG-CB 4.48Å; Y218-V237 HydrophobicContact CG-CG1 4.05Å; Y218-G238 WeakPolarHBondContact CE2-O 3.32Å; Y218-Y239 HydrophobicContact CE2-CD2 4.22Å; Y218-L241 HydrophobicContact CE1-CB 4.28Å; Y218-L241 HydrophobicContact CE1-CD2 4.42Å; Y218-L241 HydrophobicContact CE2-CB 4.15Å; Y218-L241 WeakPolarHBondContact OH-CB 3.27Å; Y218-E250 PolarHBondContact OH-OE2 2.93Å; Y218-A274 HydrophobicContact CD2-CB 4.08Å; Y218-A274 HydrophobicContact CE2-CB 3.72Å; Y218-A274 PolarHBondContact N-O 3.04Å; Y218-Y275 VanDerWaalsContact CE1-C 3.43Å; Y218-V276 HydrophobicContact CD1-CB 4.49Å; Y218-V276 HydrophobicContact CD1-CG1 4.21Å; Y218-V276 HydrophobicContact CE1-CB 4.04Å; Y218-V276 HydrophobicContact CE1-CG1 4.24Å
219E92.1Very high95.7Very high137 Ų13749 Ų4964%0.6425%0.246SC*.THydrogen-bonded Turntrans-53.3-39-177.9-169.8171.5-174.500114.2A274E219-A274 HydrophobicContact CB-CB 4.03Å
220A92.5Very high95.3Very high71 Ų7144.3 Ų44.359%0.58723%0.233SC*.THydrogen-bonded Turntrans-107.65.1178.800000113.3Y218 P222Y218-A220 VanDerWaalsContact C-N 3.26Å; Y218-A220 PolarHBondContact O-N 3.39Å; Y218-A220 VanDerWaalsContact O-N 3.16Å; A220-P222 VanDerWaalsContact O-CD 3.32Å; A220-P222 WeakPolarHBondContact O-CD 3.38Å
221L96.3Very high94.9Very high26 Ų2648.7 Ų48.714%0.13626%0.259CS..  trans-76.9122.1-172.4-176.158.9000110.2P206 L216 Y218 V226 R236 V237P206-L221 HydrophobicContact CB-CD1 4.3Å; P206-L221 HydrophobicContact CB-CD2 3.92Å; P206-L221 HydrophobicContact CG-CD1 3.95Å; P206-L221 HydrophobicContact CG-CD2 4.45Å; L216-L221 HydrophobicContact CD1-CD2 4.43Å; L216-L221 HydrophobicContact CD2-CD2 4.07Å; L216-L221 HydrophobicContact CG-CD2 4.5Å; Y218-L221 WeakPolarHBondContact O-CB 3.37Å; Y218-L221 PolarHBondContact O-N 2.92Å; L221-V226 HydrophobicContact CD2-CG2 3.7Å; L221-V226 HydrophobicContact CG-CG2 3.9Å; L221-R236 WeakPolarHBondContact O-CA 3.22Å; L221-V237 HydrophobicContact CB-CG2 4.25Å; L221-V237 HydrophobicContact CD2-CG2 4.45Å; L221-V237 HydrophobicContact CG-CG2 4.29Å; L221-V237 WeakPolarHBondContact O-CG2 3.44Å; L221-V237 PolarHBondContact O-N 3.46Å
222P97.1Very high94.7Very high26 Ų2656 Ų5617%0.16930%0.297CS..BIsolated β-bridgetrans-70.3131.4172.4-19.435.2000110.2A220 H224 E225 G233A220-P222 VanDerWaalsContact O-CD 3.32Å; A220-P222 WeakPolarHBondContact O-CD 3.38Å; P222-H224 PolarHBondContact O-N 3.16Å; P222-E225 HydrophobicContact CB-CG 4.22Å; P222-E225 WeakPolarHBondContact CG-OE1 3.42Å; P222-E225 PolarHBondContact O-N 3.14Å; P222-G233 VanDerWaalsContact CB-O 3.23Å; P222-G233 WeakPolarHBondContact CB-O 3.46Å
223R95.5Very high94.5Very high70 Ų7055.9 Ų55.926%0.26430%0.301SS..THydrogen-bonded Turntrans-66.1-25.4-171.678.9-178.1-175.71700.1113.9R163 G165 D166 E225 P235 V237R163-R223 PolarHBondContact O-NE 3.45Å; G165-R223 WeakPolarHBondContact CA-O 3.44Å; G165-R223 PolarHBondContact N-O 3.49Å; D166-R223 HydrophobicContact CB-CB 3.89Å; D166-R223 WeakPolarHBondContact OD2-CD 3.35Å; R223-E225 PolarHBondContact O-N 3.01Å; R223-P235 WeakPolarHBondContact CG-O 3.3Å; R223-P235 PolarHBondContact N-O 3.24Å; R223-V237 HydrophobicContact CB-CG2 4.09Å
224H96.4Very high94.2Very high22 Ų2252 Ų5210%0.10230%0.298CS..THydrogen-bonded Turntrans-70.8-26.2177.8-57.4172.3000111.3R163 P222 G230 V231 G233R163-H224 PolarHBondContact O-CD2 2.86Å; P222-H224 PolarHBondContact O-N 3.16Å; H224-G230 VanDerWaalsContact O-CA 3.3Å; H224-G230 WeakPolarHBondContact O-CA 3.35Å; H224-G230 PolarHBondContact O-N 3.46Å; H224-V231 VanDerWaalsContact CB-O 3.24Å; H224-V231 WeakPolarHBondContact CB-O 3.49Å; H224-G233 WeakPolarHBondContact CB-O 3.34Å; H224-G233 PolarHBondContact ND1-O 2.96Å
225E96.7Very high94.2Very high58 Ų5854.8 Ų54.827%0.27131%0.314SS..THydrogen-bonded Turntrans-86.8-15.6-176.9-64.2177.3-145.800112.8P206 P222 R223 S227 G228 L232 G233P206-E225 VanDerWaalsContact CD-O 3.31Å; P206-E225 WeakPolarHBondContact CD-O 3.29Å; P222-E225 HydrophobicContact CB-CG 4.22Å; P222-E225 WeakPolarHBondContact CG-OE1 3.42Å; P222-E225 PolarHBondContact O-N 3.14Å; R223-E225 PolarHBondContact O-N 3.01Å; E225-S227 PolarHBondContact O-N 3.44Å; E225-S227 VanDerWaalsContact O-N 3.16Å; E225-G228 PolarHBondContact O-N 3.16Å; E225-L232 HydrophobicContact CG-CD2 4.26Å; E225-G233 WeakPolarHBondContact OE1-CA 3.49Å; E225-G233 PolarHBondContact OE1-N 2.97Å
226V97.3Very high94.2Very high0 Ų057.2 Ų57.20%032%0.32CS..THydrogen-bonded Turntrans-56-38.1-174.8175.60000112.6G165 L169 P206 L207 L221 V237G165-V226 WeakPolarHBondContact O-CG1 3.36Å; L169-V226 HydrophobicContact CB-CG1 4.05Å; L169-V226 HydrophobicContact CD2-CG1 4.43Å; P206-V226 WeakPolarHBondContact CD-O 3.44Å; L207-V226 HydrophobicContact CB-CG1 4.2Å; L207-V226 VanDerWaalsContact CB-O 3.3Å; L207-V226 WeakPolarHBondContact CB-O 3.46Å; L207-V226 PolarHBondContact N-O 3.39Å; L221-V226 HydrophobicContact CD2-CG2 3.7Å; L221-V226 HydrophobicContact CG-CG2 3.9Å; V226-V237 HydrophobicContact CG2-CG2 3.71Å
227S96.3Very high94.1Very high0 Ų056.8 Ų56.80%032%0.318CS..THydrogen-bonded Turntrans-90.2-8.5178.267.70000113.9A201 T202 S205 E225 Q229A201-S227 CarbonylContact C-O 3.51Å; A201-S227 WeakPolarHBondContact CA-O 3.41Å; T202-S227 PolarHBondContact N-O 3.47Å; T202-S227 PolarHBondContact OG1-O 3.22Å; S205-S227 WeakPolarHBondContact CB-O 3.46Å; E225-S227 PolarHBondContact O-N 3.44Å; E225-S227 VanDerWaalsContact O-N 3.16Å; S227-Q229 PolarHBondContact O-N 2.9Å; S227-Q229 VanDerWaalsContact O-N 3.14Å; S227-Q229 PolarHBondContact OG-N 3.32Å
228G94.7Very high93.8Very high36 Ų3653 Ų5337%0.37131%0.312SS..SBendtrans66.63.3-174.400000115.6T202 E225T202-G228 WeakPolarHBondContact OG1-CA 3.36Å; T202-G228 PolarHBondContact OG1-O 3.2Å; E225-G228 PolarHBondContact O-N 3.16Å
229Q92.3Very high93.6Very high42 Ų4259.4 Ų59.420%0.19634%0.338CS..SBendtrans-94.5-28.6175.1-61.4177.5-62.500112.8E162 N200 T202 S227 V308E162-Q229 HydrophobicContact CB-CB 3.92Å; E162-Q229 HydrophobicContact CG-CB 3.66Å; N200-Q229 PolarHBondContact O-OE1 2.79Å; T202-Q229 HydrophobicContact CG2-CG 4.01Å; S227-Q229 PolarHBondContact O-N 2.9Å; S227-Q229 VanDerWaalsContact O-N 3.14Å; S227-Q229 PolarHBondContact OG-N 3.32Å; Q229-V308 VanDerWaalsContact NE2-CG1 3.32Å
230G87.4Confident93.6Very high15 Ų1556.9 Ų56.916%0.15533%0.333CS..SBendtrans-77.1163.1-172.600000113.6H224H224-G230 VanDerWaalsContact O-CA 3.3Å; H224-G230 WeakPolarHBondContact O-CA 3.35Å; H224-G230 PolarHBondContact O-N 3.46Å
231V90.5Very high93.6Very high91 Ų9153.9 Ų53.955%0.55231%0.307SS*.PPolyproline II helixtrans-61.3144.6170.7-630000111.1H224H224-V231 VanDerWaalsContact CB-O 3.24Å; H224-V231 WeakPolarHBondContact CB-O 3.49Å
232L91.6Very high93.5Very high156 Ų15653 Ų5382%0.81730%0.302SS*.SBendtrans-56.2138.4177.5-63.4176.6000111.7E225E225-L232 HydrophobicContact CG-CD2 4.26Å
233G91.6Very high93.3Very high24 Ų2453 Ų5325%0.24730%0.302CS..  trans87.1-145.7-179.500000114.8P222 H224 E225P222-G233 VanDerWaalsContact CB-O 3.23Å; P222-G233 WeakPolarHBondContact CB-O 3.46Å; H224-G233 WeakPolarHBondContact CB-O 3.34Å; H224-G233 PolarHBondContact ND1-O 2.96Å; E225-G233 WeakPolarHBondContact OE1-CA 3.49Å; E225-G233 PolarHBondContact OE1-N 2.97Å
234G90.8Very high93.1Very high47 Ų4758.6 Ų58.649%0.48533%0.332SS..  trans92.7-175.9-172.100000114.1
235P94.8Very high93Very high68 Ų6861.2 Ų61.244%0.44236%0.357SS..SBendtrans-61147.6177.8-20.533000111.3R223R223-P235 WeakPolarHBondContact CG-O 3.3Å; R223-P235 PolarHBondContact N-O 3.24Å
236R95.3Very high92.8Very high173 Ų17358.8 Ų58.865%0.65335%0.347SS*.BIsolated β-bridgetrans-67.8151.2172.3-64-176.2-177.2-174.71.4110.6L221 G238L221-R236 WeakPolarHBondContact O-CA 3.22Å; R236-G238 PolarHBondContact O-N 2.68Å
237V94.9Very high92.7Very high9 Ų961 Ų616%0.05537%0.365CS..PPolyproline II helixtrans-56.4132.4168.1179.90000108.9D166 Y218 L221 R223 V226 L241D166-V237 HydrophobicContact CB-CG1 4.16Å; D166-V237 HydrophobicContact CB-CG2 4.18Å; Y218-V237 HydrophobicContact CD2-CB 3.97Å; Y218-V237 HydrophobicContact CD2-CG1 3.5Å; Y218-V237 HydrophobicContact CE2-CG1 4.08Å; Y218-V237 HydrophobicContact CG-CB 4.48Å; Y218-V237 HydrophobicContact CG-CG1 4.05Å; L221-V237 HydrophobicContact CB-CG2 4.25Å; L221-V237 HydrophobicContact CD2-CG2 4.45Å; L221-V237 HydrophobicContact CG-CG2 4.29Å; L221-V237 WeakPolarHBondContact O-CG2 3.44Å; L221-V237 PolarHBondContact O-N 3.46Å; R223-V237 HydrophobicContact CB-CG2 4.09Å; V226-V237 HydrophobicContact CG2-CG2 3.71Å; V237-L241 HydrophobicContact CG1-CD1 3.77Å
238G91.9Very high92.7Very high40 Ų4061.5 Ų61.541%0.41237%0.367SS..PPolyproline II helixtrans-71.8153.3178.800000112.7Y218 R236 P240Y218-G238 WeakPolarHBondContact CE2-O 3.32Å; R236-G238 PolarHBondContact O-N 2.68Å; G238-P240 CarbonylContact O-C 3.49Å
239Y90.4Very high92.6Very high137 Ų13759.9 Ų59.954%0.53735%0.35SS..SBendtrans-122.8129.4171.1179-93.7000110.1Y218 A274Y218-Y239 HydrophobicContact CE2-CD2 4.22Å; Y239-A274 HydrophobicContact CD2-CB 3.48Å; Y239-A274 VanDerWaalsContact CD2-CB 3.48Å; Y239-A274 HydrophobicContact CE2-CB 4.1Å; Y239-A274 HydrophobicContact CG-CB 4.12Å
240P91.7Very high92.7Very high83 Ų8359 Ų5954%0.53935%0.346SS..SBendcis-64.4155-6.629.9-35.3000111.9G238 E250G238-P240 CarbonylContact O-C 3.49Å; P240-E250 WeakPolarHBondContact CB-OE1 3.17Å
241L93.4Very high92.9Very high9 Ų960.1 Ų60.15%0.04735%0.346CS..SBendtrans-71.1-49.2173.9173.673.2000110.5L169 C170 Y218 V237 E250 V276L169-L241 HydrophobicContact CB-CD1 4.47Å; L169-L241 HydrophobicContact CD2-CD1 4.07Å; L169-L241 HydrophobicContact CD2-CD2 3.79Å; L169-L241 HydrophobicContact CG-CD1 4.41Å; L169-L241 HydrophobicContact CG-CD2 3.81Å; C170-L241 WeakPolarHBondContact SG-CD1 3.31Å; C170-L241 VanDerWaalsContact SG-CG 3.52Å; C170-L241 PolarHBondContact SG-O 3.22Å; Y218-L241 HydrophobicContact CE1-CB 4.28Å; Y218-L241 HydrophobicContact CE1-CD2 4.42Å; Y218-L241 HydrophobicContact CE2-CB 4.15Å; Y218-L241 WeakPolarHBondContact OH-CB 3.27Å; V237-L241 HydrophobicContact CG1-CD1 3.77Å; L241-E250 VanDerWaalsContact CA-OE1 3.32Å; L241-E250 WeakPolarHBondContact CA-OE1 3.43Å; L241-E250 WeakPolarHBondContact CB-OE1 3.21Å; L241-E250 PolarHBondContact N-OE1 2.71Å; L241-V276 HydrophobicContact CD2-CB 4.08Å; L241-V276 HydrophobicContact CD2-CG1 4.22Å; L241-V276 HydrophobicContact CD2-CG2 4.16Å
242L93.7Very high93Very high7 Ų756.1 Ų56.14%0.03732%0.322CS..SBendtrans-89.9138.9179.5-70.3174.8000110.8C170 A173 L174 I248 E250C170-L242 HydrophobicContact CB-CD2 4.13Å; A173-L242 HydrophobicContact CB-CD1 4.07Å; A173-L242 HydrophobicContact CB-CD2 4.11Å; A173-L242 HydrophobicContact CB-CG 4.35Å; L174-L242 HydrophobicContact CD2-CD2 4.19Å; L174-L242 HydrophobicContact CG-CD2 4.15Å; L242-I248 HydrophobicContact CD1-CB 3.99Å; L242-I248 HydrophobicContact CD1-CG2 3.6Å; L242-E250 HydrophobicContact CB-CG 4.21Å; L242-E250 HydrophobicContact CD1-CG 4.09Å; L242-E250 HydrophobicContact CG-CG 4.27Å; L242-E250 PolarHBondContact N-OE1 2.82Å
243P93.1Very high93.2Very high26 Ų2648.7 Ų48.717%0.16928%0.283CS..  trans-67.9148.2171.530-34.5000110.6M117 T120 L122 A245 A246M117-P243 HydrophobicContact CE-CG 4.43Å; M117-P243 HydrophobicContact SD-CB 4.38Å; M117-P243 HydrophobicContact SD-CG 3.55Å; M117-P243 VanDerWaalsContact SD-CG 3.55Å; T120-P243 HydrophobicContact CG2-CB 3.6Å; T120-P243 HydrophobicContact CG2-CG 3.87Å; L122-P243 HydrophobicContact CD1-CG 3.89Å; P243-A245 PolarHBondContact O-N 2.94Å; P243-A245 VanDerWaalsContact O-N 3.14Å; P243-A246 HydrophobicContact CG-CB 4.32Å; P243-A246 WeakPolarHBondContact O-CB 3.23Å; P243-A246 PolarHBondContact O-N 2.86Å
244E91.6Very high93.3Very high188 Ų18849.4 Ų49.488%0.87928%0.278SS*.G310 helixtrans-54.8-35.2177.9-173.7178.2-176.700112.5A246 A247E244-A246 PolarHBondContact O-N 2.85Å; E244-A246 VanDerWaalsContact O-N 3.08Å; E244-A247 PolarHBondContact O-N 2.89Å
245A92.3Very high93.6Very high76 Ų7648.6 Ų48.663%0.62826%0.261SS*.G310 helixtrans-59.4-19176.400000114.1M117 T120 P243 A247M117-A245 HydrophobicContact CG-CB 4.47Å; M117-A245 HydrophobicContact SD-CB 3.65Å; T120-A245 HydrophobicContact CG2-CB 4.47Å; P243-A245 PolarHBondContact O-N 2.94Å; P243-A245 VanDerWaalsContact O-N 3.14Å; A245-A247 PolarHBondContact O-N 3.34Å
246A93.9Very high93.5Very high7 Ų749.4 Ų49.46%0.05826%0.259CS..G310 helixtrans-68-23.2173.400000112.8M117 L174 P243 E244 I248M117-A246 HydrophobicContact CE-CB 3.79Å; M117-A246 HydrophobicContact SD-CB 4.37Å; L174-A246 HydrophobicContact CD2-CB 3.83Å; P243-A246 HydrophobicContact CG-CB 4.32Å; P243-A246 WeakPolarHBondContact O-CB 3.23Å; P243-A246 PolarHBondContact O-N 2.86Å; E244-A246 PolarHBondContact O-N 2.85Å; E244-A246 VanDerWaalsContact O-N 3.08Å; A246-I248 HydrophobicContact CB-CB 4.44Å; A246-I248 HydrophobicContact CB-CD1 4.26Å; A246-I248 WeakPolarHBondContact O-CG1 3.31Å; A246-I248 PolarHBondContact O-N 2.82Å
247A95.2Very high93.3Very high46 Ų4644.2 Ų44.238%0.3825%0.253SS..  trans50.737.4-175.900000113.4E244 A245 F255 H256E244-A247 PolarHBondContact O-N 2.89Å; A245-A247 PolarHBondContact O-N 3.34Å; A247-F255 CarbonylContact O-C 3.53Å; A247-F255 WeakPolarHBondContact O-CA 3.47Å; A247-H256 PolarHBondContact O-CD2 2.99Å; A247-H256 PolarHBondContact O-N 2.92Å
248I95.1Very high93.1Very high11 Ų1145 Ų456%0.05626%0.257CS..EExtended strand (participates in β ladder)trans-121.2132.4-176.9-73.1157.5000109.7L174 A177 L242 A246 E250 R254 F255L174-I248 HydrophobicContact CD2-CD1 3.55Å; A177-I248 HydrophobicContact CB-CD1 3.37Å; A177-I248 HydrophobicContact CB-CG1 3.61Å; A177-I248 HydrophobicContact CB-CG2 4.08Å; L242-I248 HydrophobicContact CD1-CB 3.99Å; L242-I248 HydrophobicContact CD1-CG2 3.6Å; A246-I248 HydrophobicContact CB-CB 4.44Å; A246-I248 HydrophobicContact CB-CD1 4.26Å; A246-I248 WeakPolarHBondContact O-CG1 3.31Å; A246-I248 PolarHBondContact O-N 2.82Å; I248-E250 PolarHBondContact O-N 3.49Å; I248-R254 WeakPolarHBondContact CA-O 3.43Å; I248-F255 HydrophobicContact CD1-CD1 4.14Å; I248-F255 HydrophobicContact CD1-CE1 3.63Å; I248-F255 HydrophobicContact CD1-CZ 4.1Å; I248-F255 HydrophobicContact CG1-CD1 3.56Å; I248-F255 HydrophobicContact CG1-CE1 3.6Å; I248-F255 HydrophobicContact CG1-CG 4.27Å; I248-F255 HydrophobicContact CG1-CZ 4.33Å
249S94.1Very high92.8Very high2 Ų243.5 Ų43.51%0.01424%0.239CC..EExtended strand (participates in β ladder)trans-71.2121.8167.9166.90000109.9R251 S252 C253 R254 H256 D267S249-R251 PolarHBondContact O-N 2.99Å; S249-R251 PolarHBondContact OG-N 3.33Å; S249-S252 PolarHBondContact O-N 3.15Å; S249-S252 PolarHBondContact OG-OG 3.4Å; S249-C253 VanDerWaalsContact O-CA 3.25Å; S249-C253 WeakPolarHBondContact O-CA 3.46Å; S249-C253 PolarHBondContact O-N 3.04Å; S249-R254 PolarHBondContact N-O 3.29Å; S249-H256 PolarHBondContact N-CE1 3.11Å; S249-D267 VanDerWaalsContact CB-OD2 3.29Å; S249-D267 WeakPolarHBondContact CB-OD2 3.4Å; S249-D267 PolarHBondContact OG-OD1 3.47Å; S249-D267 PolarHBondContact OG-OD2 2.75Å
250E92.6Very high92.6Very high23 Ų2340.8 Ų40.811%0.10725%0.245CC..THydrogen-bonded Turntrans-61.4-31.7174.9-66.5-179.8163.800112.1Y218 P240 L241 L242 I248 S252 V276 G277Y218-E250 PolarHBondContact OH-OE2 2.93Å; P240-E250 WeakPolarHBondContact CB-OE1 3.17Å; L241-E250 VanDerWaalsContact CA-OE1 3.32Å; L241-E250 WeakPolarHBondContact CA-OE1 3.43Å; L241-E250 WeakPolarHBondContact CB-OE1 3.21Å; L241-E250 PolarHBondContact N-OE1 2.71Å; L242-E250 HydrophobicContact CB-CG 4.21Å; L242-E250 HydrophobicContact CD1-CG 4.09Å; L242-E250 HydrophobicContact CG-CG 4.27Å; L242-E250 PolarHBondContact N-OE1 2.82Å; I248-E250 PolarHBondContact O-N 3.49Å; E250-S252 PolarHBondContact O-N 2.8Å; E250-V276 CarbonylContact O-C 3.58Å; E250-V276 VanDerWaalsContact O-CA 3.24Å; E250-V276 WeakPolarHBondContact O-CA 3.32Å; E250-V276 WeakPolarHBondContact O-CG2 3.5Å; E250-G277 PolarHBondContact O-N 2.85Å
251R91.8Very high92Very high40 Ų4044.7 Ų44.715%0.15126%0.256CS..THydrogen-bonded Turntrans-67.9-24.7-174.3-62-177.5177.3-85.5-13.9113.7S249 D267 D271 Y275 G277S249-R251 PolarHBondContact O-N 2.99Å; S249-R251 PolarHBondContact OG-N 3.33Å; R251-D267 WeakPolarHBondContact CD-OD1 3.48Å; R251-D271 IonicContact CZ-OD2 3.33Å; R251-D271 VanDerWaalsContact NH1-CG 3.34Å; R251-D271 IonicContact NH1-OD2 3.84Å; R251-D271 PolarHBondContact NH1-OD2 3.16Å; R251-D271 PolarHBondContact NH2-O 3.4Å; R251-D271 IonicContact NH2-OD1 3.88Å; R251-D271 IonicContact NH2-OD2 2.8Å; R251-Y275 HydrophobicContact CB-CE2 4Å; R251-Y275 HydrophobicContact CG-CE1 4.5Å; R251-Y275 HydrophobicContact CG-CE2 4.05Å; R251-Y275 WeakPolarHBondContact CG-OH 3.22Å; R251-Y275 PolarHBondContact NH1-OH 3.02Å; R251-G277 CarbonylContact C-O 3.51Å; R251-G277 CarbonylContact O-C 3.57Å; R251-G277 WeakPolarHBondContact O-CA 3.42Å
252S92.9Very high91.1Very high7 Ų747.4 Ų47.45%0.04928%0.276CS..THydrogen-bonded Turntrans-132.4-5.6-173.962.70000114.1Q180 S249 E250 R254 G277Q180-S252 PolarHBondContact NE2-O 2.83Å; S249-S252 PolarHBondContact O-N 3.15Å; S249-S252 PolarHBondContact OG-OG 3.4Å; E250-S252 PolarHBondContact O-N 2.8Å; S252-R254 PolarHBondContact O-N 2.82Å; S252-G277 CarbonylContact C-O 3.56Å; S252-G277 WeakPolarHBondContact CA-O 3.46Å; S252-G277 PolarHBondContact N-O 2.77Å
253C96Very high89.8Confident0 Ų049.7 Ų49.70%030%0.301CS..THydrogen-bonded Turntrans46.348.3-168.6-700000110.8L176 A177 Q180 S249 G277 H278L176-C253 HydrophobicContact CB-CB 3.81Å; A177-C253 WeakPolarHBondContact CA-O 3.45Å; A177-C253 WeakPolarHBondContact CB-O 3.49Å; A177-C253 PolarHBondContact N-O 3.1Å; Q180-C253 PolarHBondContact NE2-O 3.03Å; S249-C253 VanDerWaalsContact O-CA 3.25Å; S249-C253 WeakPolarHBondContact O-CA 3.46Å; S249-C253 PolarHBondContact O-N 3.04Å; C253-G277 PolarHBondContact N-O 3.2Å; C253-G277 PolarHBondContact SG-O 3.34Å; C253-H278 HydrophobicContact CB-CB 4.25Å
254R94.8Very high88.3Confident38 Ų3850.7 Ų50.714%0.14331%0.309CS..EExtended strand (participates in β ladder)trans-123.5148175.7-67.7-170.769-179.6-2.7110.3I248 S249 S252 L259I248-R254 WeakPolarHBondContact CA-O 3.43Å; S249-R254 PolarHBondContact N-O 3.29Å; S252-R254 PolarHBondContact O-N 2.82Å; R254-L259 HydrophobicContact CB-CD1 4.29Å; R254-L259 HydrophobicContact CB-CD2 3.99Å; R254-L259 HydrophobicContact CB-CG 4Å
255F95.2Very high86.7Confident30 Ų3050.5 Ų50.513%0.13231%0.308CS..EExtended strand (participates in β ladder)trans-61.3138.4173.3-66.5-73.2000110.7A177 H178 Q181 A247 I248 A257 D258 L259A177-F255 HydrophobicContact CB-CD2 4.29Å; A177-F255 HydrophobicContact CB-CE1 4.44Å; A177-F255 HydrophobicContact CB-CE2 3.87Å; A177-F255 HydrophobicContact CB-CZ 3.93Å; H178-F255 AromaticContact CD2-CZ 3.81Å; H178-F255 AromaticContact CE1-CZ 3.53Å; H178-F255 AromaticContact CG-CZ 3.92Å; H178-F255 AromaticContact ND1-CZ 3.73Å; H178-F255 AromaticContact NE2-CZ 3.58Å; Q181-F255 HydrophobicContact CB-CD2 4.36Å; Q181-F255 HydrophobicContact CB-CE2 4.37Å; A247-F255 CarbonylContact O-C 3.53Å; A247-F255 WeakPolarHBondContact O-CA 3.47Å; I248-F255 HydrophobicContact CD1-CD1 4.14Å; I248-F255 HydrophobicContact CD1-CE1 3.63Å; I248-F255 HydrophobicContact CD1-CZ 4.1Å; I248-F255 HydrophobicContact CG1-CD1 3.56Å; I248-F255 HydrophobicContact CG1-CE1 3.6Å; I248-F255 HydrophobicContact CG1-CG 4.27Å; I248-F255 HydrophobicContact CG1-CZ 4.33Å; F255-A257 PolarHBondContact O-N 2.93Å; F255-D258 PolarHBondContact O-N 2.91Å; F255-L259 PolarHBondContact O-N 2.86Å; F255-L259 VanDerWaalsContact O-N 3.16Å
256H93.9Very high84.9Confident86 Ų8649.1 Ų49.140%0.39830%0.296SS..Hα-helixtrans-57.4-35176.9-66.2-54.6000112.1A247 S249 D258 L259 A260 D267A247-H256 PolarHBondContact O-CD2 2.99Å; A247-H256 PolarHBondContact O-N 2.92Å; S249-H256 PolarHBondContact N-CE1 3.11Å; H256-D258 VanDerWaalsContact C-N 3.34Å; H256-D258 PolarHBondContact O-N 3.28Å; H256-L259 PolarHBondContact O-N 3.44Å; H256-A260 WeakPolarHBondContact O-CB 3.49Å; H256-A260 PolarHBondContact O-N 3.49Å; H256-D267 IonicContact CE1-OD2 3.94Å; H256-D267 IonicContact ND1-OD2 2.95Å
257A91.7Very high83.1Confident63 Ų6352 Ų5252%0.52131%0.31SS..Hα-helixtrans-60.2-40.8175.600000112.7F255 Q261F255-A257 PolarHBondContact O-N 2.93Å; A257-Q261 WeakPolarHBondContact O-CG 3.45Å; A257-Q261 PolarHBondContact O-N 3.39Å
258D88.9Confident81Confident25 Ų2553 Ų5313%0.13432%0.315CS..Hα-helixtrans-71.8-36.4179.1-63.1-14.5000111.2Q181 F255 H256 S262Q181-D258 WeakPolarHBondContact CG-OD2 3.37Å; Q181-D258 PolarHBondContact NE2-OD1 2.66Å; Q181-D258 VanDerWaalsContact NE2-OD1 3.09Å; Q181-D258 PolarHBondContact NE2-OD2 2.88Å; Q181-D258 VanDerWaalsContact NE2-OD2 3.16Å; F255-D258 PolarHBondContact O-N 2.91Å; H256-D258 VanDerWaalsContact C-N 3.34Å; H256-D258 PolarHBondContact O-N 3.28Å; D258-S262 PolarHBondContact O-N 3.48Å
259L86.8Confident79.1Confident9 Ų957.2 Ų57.25%0.04735%0.351CS..Hα-helixtrans-67.2-43.4177.4-67.1172.8000111.6R254 F255 H256 Q261 S262 G263 S264R254-L259 HydrophobicContact CB-CD1 4.29Å; R254-L259 HydrophobicContact CB-CD2 3.99Å; R254-L259 HydrophobicContact CB-CG 4Å; F255-L259 PolarHBondContact O-N 2.86Å; F255-L259 VanDerWaalsContact O-N 3.16Å; H256-L259 PolarHBondContact O-N 3.44Å; L259-Q261 VanDerWaalsContact C-N 3.28Å; L259-Q261 PolarHBondContact O-N 2.81Å; L259-S262 PolarHBondContact O-N 2.86Å; L259-S262 VanDerWaalsContact O-N 3.09Å; L259-S262 PolarHBondContact O-OG 3.1Å; L259-G263 PolarHBondContact O-N 2.97Å; L259-S264 WeakPolarHBondContact CD2-OG 3.38Å
260A85.6Confident77.2Confident80 Ų8064.8 Ų64.866%0.66139%0.391SS*.Hα-helixtrans-59.1-38.1178.100000112.4H256 S262H256-A260 WeakPolarHBondContact O-CB 3.49Å; H256-A260 PolarHBondContact O-N 3.49Å; A260-S262 VanDerWaalsContact C-N 3.33Å; A260-S262 PolarHBondContact O-N 3.46Å
261Q79.7Confident75.7Confident165 Ų16566.1 Ų66.177%0.77140%0.399SS*.Hα-helixtrans-69.1-30.1177-69.6173.625.700113.2A257 L259A257-Q261 WeakPolarHBondContact O-CG 3.45Å; A257-Q261 PolarHBondContact O-N 3.39Å; L259-Q261 VanDerWaalsContact C-N 3.28Å; L259-Q261 PolarHBondContact O-N 2.81Å
262S73.1Confident74.7Confident66 Ų6672.8 Ų72.846%0.46243%0.429SS..THydrogen-bonded Turntrans-84.7-5.2-178.269.30000114.6D258 L259 A260 S264D258-S262 PolarHBondContact O-N 3.48Å; L259-S262 PolarHBondContact O-N 2.86Å; L259-S262 VanDerWaalsContact O-N 3.09Å; L259-S262 PolarHBondContact O-OG 3.1Å; A260-S262 VanDerWaalsContact C-N 3.33Å; A260-S262 PolarHBondContact O-N 3.46Å; S262-S264 PolarHBondContact O-N 2.95Å; S262-S264 PolarHBondContact OG-OG 3.49Å; S262-S264 VanDerWaalsContact OG-OG 3.07Å
263G68.1Low74.2Confident55 Ų5577 Ų7757%0.56745%0.448SS*.THydrogen-bonded Turntrans68.47.7-174.300000114.2L259 H265L259-G263 PolarHBondContact O-N 2.97Å; G263-H265 PolarHBondContact O-N 3.45Å; G263-H265 VanDerWaalsContact O-N 3.17Å
264S61.7Low73.9Confident48 Ų4877.4 Ų77.434%0.33645%0.451SS..  trans-75.8104.6176.770.30000110.1L259 S262 A266L259-S264 WeakPolarHBondContact CD2-OG 3.38Å; S262-S264 PolarHBondContact O-N 2.95Å; S262-S264 PolarHBondContact OG-OG 3.49Å; S262-S264 VanDerWaalsContact OG-OG 3.07Å; S264-A266 PolarHBondContact O-N 3.16Å
265H56.6Low73.9Confident184 Ų18476.9 Ų76.985%0.85245%0.449SS*.  trans-7459.7163.2-66.5-69000109.8G263 D267G263-H265 PolarHBondContact O-N 3.45Å; G263-H265 VanDerWaalsContact O-N 3.17Å; H265-D267 VanDerWaalsContact C-N 3.28Å; H265-D267 PolarHBondContact O-N 3.41Å
266A54.6Low73.9Confident46 Ų4675.4 Ų75.438%0.3844%0.443SS..  trans-70.7-26.2-174.900000112.5S264 S268S264-A266 PolarHBondContact O-N 3.16Å; A266-S268 PolarHBondContact O-N 3.29Å
267D56.2Low74Confident67 Ų6771.4 Ų71.436%0.35842%0.424SS..  trans-98.970.9177.1-60.3-29.8000109.2S249 R251 H256 H265 A269S249-D267 VanDerWaalsContact CB-OD2 3.29Å; S249-D267 WeakPolarHBondContact CB-OD2 3.4Å; S249-D267 PolarHBondContact OG-OD1 3.47Å; S249-D267 PolarHBondContact OG-OD2 2.75Å; R251-D267 WeakPolarHBondContact CD-OD1 3.48Å; H256-D267 IonicContact CE1-OD2 3.94Å; H256-D267 IonicContact ND1-OD2 2.95Å; H265-D267 VanDerWaalsContact C-N 3.28Å; H265-D267 PolarHBondContact O-N 3.41Å; D267-A269 PolarHBondContact O-N 3.29Å; D267-A269 VanDerWaalsContact O-N 3.09Å
268S52.5Low74.2Confident68 Ų6869.2 Ų69.248%0.47640%0.403SS..  trans-63.9115.4164.777.50000107.1A266 L270 D271A266-S268 PolarHBondContact O-N 3.29Å; S268-L270 PolarHBondContact O-N 2.99Å; S268-D271 PolarHBondContact O-N 2.91Å
269A53.9Low74.4Confident99 Ų9972.8 Ų72.882%0.81842%0.419SS*.THydrogen-bonded Turntrans-57.2-4.3-17700000115.1D267D267-A269 PolarHBondContact O-N 3.29Å; D267-A269 VanDerWaalsContact O-N 3.09Å
270L53.8Low74.7Confident162 Ų16272.6 Ų72.685%0.84842%0.418SS*.THydrogen-bonded Turntrans-84.1-23.2-177.8-71165.2000114S268 K272S268-L270 PolarHBondContact O-N 2.99Å; L270-K272 PolarHBondContact O-N 3.24Å
271D62.7Low75.1Confident51 Ų5176.3 Ų76.327%0.27342%0.419SS..  trans-86113.6177.8-172.33.9000109.4R251 S268 Q273R251-D271 IonicContact CZ-OD2 3.33Å; R251-D271 VanDerWaalsContact NH1-CG 3.34Å; R251-D271 IonicContact NH1-OD2 3.84Å; R251-D271 PolarHBondContact NH1-OD2 3.16Å; R251-D271 PolarHBondContact NH2-O 3.4Å; R251-D271 IonicContact NH2-OD1 3.88Å; R251-D271 IonicContact NH2-OD2 2.8Å; S268-D271 PolarHBondContact O-N 2.91Å; D271-Q273 WeakPolarHBondContact OD1-CB 3.38Å; D271-Q273 VanDerWaalsContact OD1-CG 3.3Å; D271-Q273 WeakPolarHBondContact OD1-CG 3.35Å; D271-Q273 PolarHBondContact OD1-N 2.94Å; D271-Q273 VanDerWaalsContact OD1-N 3.1Å
272K70.6Confident75.9Confident179 Ų17968.8 Ų68.878%0.77838%0.384SS*.  trans-96.95.6-178.7-68.2-173.7178.3-178.40113L270 A274L270-K272 PolarHBondContact O-N 3.24Å; K272-A274 PolarHBondContact O-N 2.75Å
273Q82.2Confident77Confident97 Ų9768.4 Ų68.445%0.45338%0.379SS..  trans-68128-179.1-68.7-179.9-4.700111.1F217 D271 Y275F217-Q273 HydrophobicContact CE1-CB 4.41Å; D271-Q273 WeakPolarHBondContact OD1-CB 3.38Å; D271-Q273 VanDerWaalsContact OD1-CG 3.3Å; D271-Q273 WeakPolarHBondContact OD1-CG 3.35Å; D271-Q273 PolarHBondContact OD1-N 2.94Å; D271-Q273 VanDerWaalsContact OD1-N 3.1Å; Q273-Y275 HydrophobicContact CB-CD1 4.09Å; Q273-Y275 PolarHBondContact O-N 2.66Å
274A89.8Confident78.3Confident7 Ų766.9 Ų66.96%0.05836%0.359CS..  trans-78.187.9175.300000109.9Y218 E219 Y239 K272Y218-A274 HydrophobicContact CD2-CB 4.08Å; Y218-A274 HydrophobicContact CE2-CB 3.72Å; Y218-A274 PolarHBondContact N-O 3.04Å; E219-A274 HydrophobicContact CB-CB 4.03Å; Y239-A274 HydrophobicContact CD2-CB 3.48Å; Y239-A274 VanDerWaalsContact CD2-CB 3.48Å; Y239-A274 HydrophobicContact CE2-CB 4.1Å; Y239-A274 HydrophobicContact CG-CB 4.12Å; K272-A274 PolarHBondContact O-N 2.75Å
275Y94.3Very high79.9Confident27 Ų2764.7 Ų64.711%0.10634%0.344CS..EExtended strand (participates in β ladder)trans-136.9149.4173.281.7-100.4000112.3L216 F217 Y218 R251 Q273L216-Y275 CarbonylContact O-C 3.52Å; L216-Y275 WeakPolarHBondContact O-CA 3.16Å; L216-Y275 WeakPolarHBondContact O-CB 3.42Å; F217-Y275 HydrophobicContact CD1-CD1 4.32Å; F217-Y275 HydrophobicContact CD1-CG 4.29Å; F217-Y275 AromaticContact CE1-CD1 3.78Å; F217-Y275 HydrophobicContact CE1-CD1 3.78Å; F217-Y275 HydrophobicContact CE1-CG 4.02Å; F217-Y275 HydrophobicContact CZ-CD1 4.41Å; F217-Y275 HydrophobicContact CZ-CG 4.5Å; Y218-Y275 VanDerWaalsContact CE1-C 3.43Å; R251-Y275 HydrophobicContact CB-CE2 4Å; R251-Y275 HydrophobicContact CG-CE1 4.5Å; R251-Y275 HydrophobicContact CG-CE2 4.05Å; R251-Y275 WeakPolarHBondContact CG-OH 3.22Å; R251-Y275 PolarHBondContact NH1-OH 3.02Å; Q273-Y275 HydrophobicContact CB-CD1 4.09Å; Q273-Y275 PolarHBondContact O-N 2.66Å
276V95.8Very high81.6Confident0 Ų056.2 Ų56.20%030%0.304CS..EExtended strand (participates in β ladder)trans-111.6142.4171.9640000108.8L169 A173 F210 K215 L216 Y218 L241 E250L169-V276 HydrophobicContact CD1-CG1 4.26Å; L169-V276 HydrophobicContact CD2-CG1 4.17Å; L169-V276 HydrophobicContact CG-CG1 4.39Å; A173-V276 HydrophobicContact CB-CG2 4.19Å; F210-V276 HydrophobicContact CD2-CG1 3.88Å; F210-V276 HydrophobicContact CE1-CG1 4.38Å; F210-V276 HydrophobicContact CE1-CG2 4.37Å; F210-V276 HydrophobicContact CE2-CB 4.24Å; F210-V276 HydrophobicContact CE2-CG1 3.73Å; F210-V276 HydrophobicContact CE2-CG2 3.91Å; F210-V276 HydrophobicContact CG-CG1 4.29Å; F210-V276 HydrophobicContact CZ-CB 4.37Å; F210-V276 HydrophobicContact CZ-CG1 3.99Å; F210-V276 HydrophobicContact CZ-CG2 3.63Å; K215-V276 CarbonylContact C-O 3.53Å; K215-V276 WeakPolarHBondContact CA-O 3.42Å; L216-V276 HydrophobicContact CB-CG1 4.08Å; L216-V276 PolarHBondContact N-O 2.89Å; L216-V276 PolarHBondContact O-N 2.89Å; Y218-V276 HydrophobicContact CD1-CB 4.49Å; Y218-V276 HydrophobicContact CD1-CG1 4.21Å; Y218-V276 HydrophobicContact CE1-CB 4.04Å; Y218-V276 HydrophobicContact CE1-CG1 4.24Å; L241-V276 HydrophobicContact CD2-CB 4.08Å; L241-V276 HydrophobicContact CD2-CG1 4.22Å; L241-V276 HydrophobicContact CD2-CG2 4.16Å; E250-V276 CarbonylContact O-C 3.58Å; E250-V276 VanDerWaalsContact O-CA 3.24Å; E250-V276 WeakPolarHBondContact O-CA 3.32Å; E250-V276 WeakPolarHBondContact O-CG2 3.5Å
277G96.4Very high82.7Confident1 Ų156.8 Ų56.81%0.0130%0.301CS..EExtended strand (participates in β ladder)trans-147.5157.5-175.500000113.2G214 E250 R251 S252 C253G214-G277 CarbonylContact O-C 3.54Å; G214-G277 WeakPolarHBondContact O-CA 3.43Å; E250-G277 PolarHBondContact O-N 2.85Å; R251-G277 CarbonylContact C-O 3.51Å; R251-G277 CarbonylContact O-C 3.57Å; R251-G277 WeakPolarHBondContact O-CA 3.42Å; S252-G277 CarbonylContact C-O 3.56Å; S252-G277 WeakPolarHBondContact CA-O 3.46Å; S252-G277 PolarHBondContact N-O 2.77Å; C253-G277 PolarHBondContact N-O 3.2Å; C253-G277 PolarHBondContact SG-O 3.34Å
278H95.5Very high83.2Confident17 Ų1755.4 Ų55.48%0.07930%0.296CS..  trans-142.6168.7172.666.875.4000111.7L176 F210 L211 G214 C253 L280 F282L176-H278 HydrophobicContact CD1-CB 4.03Å; L176-H278 VanDerWaalsContact CD1-CD2 3.49Å; L176-H278 WeakPolarHBondContact CD1-CD2 3.48Å; F210-H278 AromaticContact CE2-CD2 3.62Å; F210-H278 AromaticContact CZ-CD2 3.75Å; F210-H278 PolarHBondContact O-NE2 3.49Å; F210-H278 VanDerWaalsContact O-NE2 3.15Å; L211-H278 WeakPolarHBondContact CA-NE2 3.36Å; L211-H278 PolarHBondContact O-CE1 2.92Å; L211-H278 PolarHBondContact O-NE2 3.06Å; L211-H278 VanDerWaalsContact O-NE2 3.14Å; G214-H278 PolarHBondContact O-N 3.47Å; C253-H278 HydrophobicContact CB-CB 4.25Å; H278-L280 PolarHBondContact CE1-O 3.21Å; H278-L280 PolarHBondContact ND1-N 3.16Å; H278-L280 PolarHBondContact ND1-O 3.23Å; H278-F282 AromaticContact CE1-CD2 3.61Å
279Q92.2Very high83.5Confident101 Ų10157.8 Ų57.847%0.47230%0.3SS..SBendtrans-104.8-12.7-175.1-61.6-1757.100113.9F190F190-Q279 HydrophobicContact CE2-CB 3.64Å; F190-Q279 HydrophobicContact CZ-CB 4.1Å
280L94.4Very high83.5Confident5 Ų560.9 Ų60.93%0.02630%0.297CS..  trans-65.3136.3172.5-62.8173.3000110L176 L179 Q180 F190 V193 H278 F282L176-L280 HydrophobicContact CD2-CD1 4.21Å; L179-L280 HydrophobicContact CD2-CD1 4.03Å; L179-L280 HydrophobicContact CG-CD1 4.04Å; Q180-L280 HydrophobicContact CG-CD1 3.87Å; Q180-L280 HydrophobicContact CG-CD2 4.4Å; Q180-L280 HydrophobicContact CG-CG 3.85Å; F190-L280 HydrophobicContact CB-CD2 3.93Å; F190-L280 HydrophobicContact CD1-CD2 4.24Å; F190-L280 HydrophobicContact CD2-CD2 3.86Å; F190-L280 HydrophobicContact CE2-CD2 4.48Å; F190-L280 HydrophobicContact CG-CD2 3.72Å; V193-L280 HydrophobicContact CG2-CD2 3.97Å; H278-L280 PolarHBondContact CE1-O 3.21Å; H278-L280 PolarHBondContact ND1-N 3.16Å; H278-L280 PolarHBondContact ND1-O 3.23Å; L280-F282 HydrophobicContact CB-CD2 4.09Å; L280-F282 HydrophobicContact CB-CE2 3.69Å; L280-F282 HydrophobicContact CB-CZ 3.94Å; L280-F282 HydrophobicContact CD1-CE1 4.42Å; L280-F282 HydrophobicContact CD1-CE2 3.81Å; L280-F282 HydrophobicContact CD1-CZ 3.51Å; L280-F282 HydrophobicContact CG-CE2 4.4Å; L280-F282 HydrophobicContact CG-CZ 4.35Å; L280-F282 PolarHBondContact O-N 3.14Å
281K93.8Very high83.3Confident157 Ų15759.1 Ų59.168%0.68330%0.296SS*.  trans-100.275-179.6-65.7-176.2-179.5-177.90109.1T283 S314K281-T283 PolarHBondContact O-N 3.25Å; K281-S314 PolarHBondContact N-OG 3.39Å; K281-S314 WeakPolarHBondContact O-CA 3.32Å
282F96.4Very high83Confident7 Ų759 Ų593%0.03130%0.299CS..  trans-70129.5-177.1-73.3-61.2000111.8L176 L179 V193 L195 L211 H278 L280 F312 Y313L176-F282 HydrophobicContact CD2-CE2 3.61Å; L176-F282 HydrophobicContact CD2-CZ 4.12Å; L179-F282 HydrophobicContact CD2-CZ 4.16Å; V193-F282 HydrophobicContact CB-CE1 4.49Å; V193-F282 HydrophobicContact CG1-CE1 3.99Å; V193-F282 HydrophobicContact CG1-CZ 4.29Å; L195-F282 HydrophobicContact CB-CE1 3.71Å; L195-F282 HydrophobicContact CB-CZ 3.91Å; L195-F282 HydrophobicContact CD2-CE1 4.26Å; L195-F282 HydrophobicContact CD2-CE2 4.03Å; L195-F282 HydrophobicContact CD2-CZ 3.73Å; L195-F282 HydrophobicContact CG-CZ 4.48Å; L211-F282 HydrophobicContact CD2-CD2 4.24Å; L211-F282 HydrophobicContact CD2-CE2 4.23Å; L211-F282 WeakPolarHBondContact O-CB 3.25Å; H278-F282 AromaticContact CE1-CD2 3.61Å; L280-F282 HydrophobicContact CB-CD2 4.09Å; L280-F282 HydrophobicContact CB-CE2 3.69Å; L280-F282 HydrophobicContact CB-CZ 3.94Å; L280-F282 HydrophobicContact CD1-CE1 4.42Å; L280-F282 HydrophobicContact CD1-CE2 3.81Å; L280-F282 HydrophobicContact CD1-CZ 3.51Å; L280-F282 HydrophobicContact CG-CE2 4.4Å; L280-F282 HydrophobicContact CG-CZ 4.35Å; L280-F282 PolarHBondContact O-N 3.14Å; F282-F312 HydrophobicContact CB-CB 4.02Å; F282-F312 HydrophobicContact CB-CD1 4.45Å; F282-F312 HydrophobicContact CB-CG 4.5Å; F282-F312 HydrophobicContact CD1-CB 3.64Å; F282-F312 HydrophobicContact CE1-CB 4.36Å; F282-F312 HydrophobicContact CG-CB 3.99Å; F282-Y313 CarbonylContact C-O 3.59Å; F282-Y313 WeakPolarHBondContact CA-O 3.22Å
283T95.7Very high82.5Confident59 Ų5960.3 Ų60.336%0.36231%0.308SS..EExtended strand (participates in β ladder)trans-106.1129165.9-56.10000107.7K281 F312 Y313K281-T283 PolarHBondContact O-N 3.25Å; T283-F312 WeakPolarHBondContact O-CA 3.48Å; T283-Y313 HydrophobicContact CG2-CE1 3.79Å; T283-Y313 PolarHBondContact N-O 2.94Å; T283-Y313 WeakPolarHBondContact O-CD1 3.33Å; T283-Y313 PolarHBondContact O-N 3.49Å
284P95.5Very high81.8Confident23 Ų2358.3 Ų58.315%0.14930%0.3CS..EExtended strand (participates in β ladder)trans-67134.9174.928.9-33.8000110.2Y208 T212 D287 F312Y208-P284 HydrophobicContact CE2-CB 4.46Å; Y208-P284 WeakPolarHBondContact OH-CB 3.39Å; Y208-P284 VanDerWaalsContact OH-CG 3.31Å; Y208-P284 WeakPolarHBondContact OH-CG 3.18Å; T212-P284 HydrophobicContact CG2-CG 4.36Å; P284-D287 HydrophobicContact CG-CB 4.07Å; P284-F312 HydrophobicContact CB-CD1 4.04Å; P284-F312 HydrophobicContact CB-CE1 4.08Å
285V95.5Very high81.3Confident2 Ų264.2 Ų64.21%0.01233%0.33CS..SBendtrans-73.5-38.4173.9172.80000110.2M311 Y313 R339 A369 F371V285-M311 HydrophobicContact CB-CB 4.04Å; V285-M311 HydrophobicContact CB-CG 4.08Å; V285-M311 WeakPolarHBondContact CB-O 3.36Å; V285-M311 HydrophobicContact CB-SD 4.2Å; V285-M311 HydrophobicContact CG1-SD 4.06Å; V285-M311 HydrophobicContact CG2-CB 4.14Å; V285-M311 HydrophobicContact CG2-CG 3.67Å; V285-M311 HydrophobicContact CG2-SD 3.89Å; V285-M311 PolarHBondContact N-O 3.23Å; V285-Y313 HydrophobicContact CG2-CD1 3.7Å; V285-Y313 HydrophobicContact CG2-CE1 4.32Å; V285-R339 HydrophobicContact CG1-CB 4.22Å; V285-R339 WeakPolarHBondContact O-CD 3.44Å; V285-R339 PolarHBondContact O-NE 3.19Å; V285-R339 PolarHBondContact O-NH1 3.3Å; V285-A369 HydrophobicContact CG1-CB 3.56Å; V285-F371 HydrophobicContact CG2-CE1 4.09Å; V285-F371 HydrophobicContact CG2-CZ 3.78Å
286Y91.2Very high81Confident5 Ų564.6 Ų64.62%0.0233%0.332CS..SBendtrans-110.4104.9174.8-67.3-99.9000107.5W307 R339 L340 L342 L367 L368Y286-W307 VanDerWaalsContact CB-CZ2 3.42Å; Y286-W307 HydrophobicContact CG-CZ2 4.39Å; Y286-R339 HydrophobicContact CD1-CG 4.37Å; Y286-R339 HydrophobicContact CE1-CB 4.14Å; Y286-R339 HydrophobicContact CE1-CG 4.06Å; Y286-R339 HydrophobicContact CE2-CB 4.34Å; Y286-L340 VanDerWaalsContact CE1-O 3.24Å; Y286-L340 WeakPolarHBondContact CE1-O 3.41Å; Y286-L340 PolarHBondContact OH-O 3.49Å; Y286-L342 HydrophobicContact CD1-CD1 3.85Å; Y286-L342 HydrophobicContact CD1-CG 4.04Å; Y286-L342 HydrophobicContact CE1-CD1 4.06Å; Y286-L342 HydrophobicContact CE1-CD2 4.35Å; Y286-L342 HydrophobicContact CE1-CG 3.8Å; Y286-L367 HydrophobicContact CD2-CD1 4.4Å; Y286-L367 HydrophobicContact CE1-CD2 4.43Å; Y286-L367 HydrophobicContact CE2-CB 3.84Å; Y286-L367 HydrophobicContact CE2-CD1 4.38Å; Y286-L367 HydrophobicContact CE2-CD2 4.28Å; Y286-L367 HydrophobicContact CE2-CG 4.4Å; Y286-L368 PolarHBondContact OH-N 2.91Å; Y286-L368 PolarHBondContact OH-O 3.41Å
287D79.2Confident80.7Confident59 Ų5964.7 Ų64.732%0.31633%0.332SS..  trans-107.9133.6-175.8-172.75.3000110.2P284 E289P284-D287 HydrophobicContact CG-CB 4.07Å; D287-E289 PolarHBondContact OD1-N 3.37Å
288C65.9Low80.6Confident37 Ų3764.6 Ų64.625%0.2533%0.332CS..  trans-115.82.2-178.2-31.60000112.4Q290 W307C288-Q290 CarbonylContact C-O 3.54Å; C288-Q290 CarbonylContact O-C 2.89Å; C288-Q290 PolarHBondContact O-N 2.93Å; C288-Q290 VanDerWaalsContact O-N 3.1Å; C288-Q290 VanDerWaalsContact O-O 3.12Å; C288-W307 WeakPolarHBondContact SG-CH2 3.32Å; C288-W307 WeakPolarHBondContact SG-CZ3 3.36Å
289E58.4Low80.5Confident119 Ų11965.3 Ų65.356%0.55633%0.334SS*.SBendtrans-61.2-19.4177.6-74.6-168.8178.500111.1K213 D287K213-E289 IonicContact NZ-OE1 2.7Å; K213-E289 PolarHBondContact NZ-OE1 3.47Å; D287-E289 PolarHBondContact OD1-N 3.37Å
290Q53.6Low80.6Confident163 Ų16360.5 Ų60.576%0.76231%0.312SS*.SBendtrans-86.9121.8163.1-62.6-166.4-1.400109.6C288 S292C288-Q290 CarbonylContact C-O 3.54Å; C288-Q290 CarbonylContact O-C 2.89Å; C288-Q290 PolarHBondContact O-N 2.93Å; C288-Q290 VanDerWaalsContact O-N 3.1Å; C288-Q290 VanDerWaalsContact O-O 3.12Å; Q290-S292 VanDerWaalsContact C-N 3.34Å; Q290-S292 PolarHBondContact O-N 3.31Å
291P49.9Very low80.4Confident126 Ų12661.6 Ų61.682%0.81832%0.318SS*.  trans-58.7100.6174.921.6-29.2000108.9
292S56.5Low80.1Confident49 Ų4954.3 Ų54.334%0.34329%0.287SS..  trans-68.8132.4165.4163.10000106.8Q290 I294Q290-S292 VanDerWaalsContact C-N 3.34Å; Q290-S292 PolarHBondContact O-N 3.31Å; S292-I294 WeakPolarHBondContact CB-O 3.15Å; S292-I294 PolarHBondContact O-N 3.23Å; S292-I294 VanDerWaalsContact O-N 3.16Å; S292-I294 WeakPolarHBondContact OG-CA 3.3Å; S292-I294 WeakPolarHBondContact OG-CB 3.36Å; S292-I294 PolarHBondContact OG-N 2.95Å; S292-I294 PolarHBondContact OG-O 3.44Å
293E60.4Low79.5Confident205 Ų20560.4 Ų60.496%0.95832%0.318SS*.SBendtrans-61.7-17169-68.1-175.6169.300111.6
294I66.9Low79.1Confident55 Ų5562.1 Ų62.128%0.28233%0.325SS..SBendtrans-102.9120.3-175.7-50.1178.2000109S292 W296S292-I294 WeakPolarHBondContact CB-O 3.15Å; S292-I294 PolarHBondContact O-N 3.23Å; S292-I294 VanDerWaalsContact O-N 3.16Å; S292-I294 WeakPolarHBondContact OG-CA 3.3Å; S292-I294 WeakPolarHBondContact OG-CB 3.36Å; S292-I294 PolarHBondContact OG-N 2.95Å; S292-I294 PolarHBondContact OG-O 3.44Å; I294-W296 PolarHBondContact O-N 3.14Å
295D80.2Confident78.9Confident132 Ų13263.4 Ų63.471%0.70633%0.332SS*.  trans-76.787.2171.1-168.524.1000109.2S344D295-S344 WeakPolarHBondContact O-CA 3.43Å
296W86.7Confident78.6Confident35 Ų3564.3 Ų64.313%0.13334%0.342CS..BIsolated β-bridgetrans-64.5138.5-179.1-68.7-26.5000111.3I294 W307 L342I294-W296 PolarHBondContact O-N 3.14Å; W296-W307 HydrophobicContact CB-CE3 4.09Å; W296-W307 HydrophobicContact CB-CZ3 3.98Å; W296-W307 HydrophobicContact CD2-CZ3 4.46Å; W296-W307 AromaticContact CE3-CH2 3.88Å; W296-W307 HydrophobicContact CE3-CH2 3.88Å; W296-W307 AromaticContact CE3-CZ3 3.64Å; W296-W307 HydrophobicContact CE3-CZ3 3.64Å; W296-W307 HydrophobicContact CZ3-CH2 4.45Å; W296-L342 HydrophobicContact CB-CB 3.83Å; W296-L342 HydrophobicContact CB-CD1 4.2Å; W296-L342 HydrophobicContact CD2-CB 4.1Å; W296-L342 HydrophobicContact CG-CB 3.66Å; W296-L342 PolarHBondContact NE1-O 3.33Å; W296-L342 VanDerWaalsContact NE1-O 3.09Å
297V91.4Very high78.6Confident1 Ų165.1 Ų65.11%0.00635%0.345CS..  trans-120.3145.8175.9-57.30000110.3V300 G306 L343 C345 I348V297-V300 HydrophobicContact CG2-CG2 3.89Å; V297-G306 CarbonylContact C-O 3.54Å; V297-G306 WeakPolarHBondContact CA-O 3.4Å; V297-L343 PolarHBondContact N-O 3.16Å; V297-C345 HydrophobicContact CG1-CB 4.16Å; V297-I348 HydrophobicContact CG2-CD1 3.41Å; V297-I348 VanDerWaalsContact CG2-CD1 3.41Å
298S93Very high79.4Confident0 Ų062.5 Ų62.50%033%0.332CS..SBendtrans-104.2-10171.380.80000112.4G306 V308 D309 H364 I365S298-G306 PolarHBondContact N-O 3.38Å; S298-V308 PolarHBondContact OG-N 3.07Å; S298-D309 WeakPolarHBondContact CB-OD2 3.29Å; S298-D309 PolarHBondContact OG-N 3.07Å; S298-D309 VanDerWaalsContact OG-N 3.1Å; S298-D309 PolarHBondContact OG-OD2 2.7Å; S298-H364 CarbonylContact O-C 3.5Å; S298-H364 VanDerWaalsContact O-CA 3.29Å; S298-H364 WeakPolarHBondContact O-CA 3.31Å; S298-I365 PolarHBondContact O-N 2.95Å
299F94.1Very high80.9Confident31 Ų3160.8 Ų60.814%0.13632%0.32CS..EExtended strand (participates in β ladder)trans-148.6155172.979.7-82.3000112.8I301 T305 G306 V308 D363F299-I301 HydrophobicContact CD2-CB 4.49Å; F299-I301 HydrophobicContact CD2-CD1 3.84Å; F299-I301 HydrophobicContact CD2-CG1 3.92Å; F299-I301 HydrophobicContact CE2-CD1 4.15Å; F299-I301 HydrophobicContact CE2-CG1 4.42Å; F299-T305 WeakPolarHBondContact O-CA 3.14Å; F299-G306 WeakPolarHBondContact CD1-O 3.21Å; F299-G306 VanDerWaalsContact CE1-C 3.49Å; F299-G306 VanDerWaalsContact CE1-CA 3.46Å; F299-G306 PolarHBondContact N-O 3.27Å; F299-V308 HydrophobicContact CD1-CG1 4.29Å; F299-V308 HydrophobicContact CD1-CG2 3.71Å; F299-V308 HydrophobicContact CE1-CG1 3.89Å; F299-V308 HydrophobicContact CE1-CG2 4.15Å; F299-D363 CarbonylContact C-O 3.58Å; F299-D363 VanDerWaalsContact CA-O 3.27Å; F299-D363 WeakPolarHBondContact CA-O 3.44Å
300V93.4Very high82.7Confident0 Ų055.4 Ų55.40%030%0.295CS..EExtended strand (participates in β ladder)trans-139.6107.3175.2-177.80000110.1V297 T305 I348 L349 L355 D363V297-V300 HydrophobicContact CG2-CG2 3.89Å; V300-T305 HydrophobicContact CB-CG2 4.17Å; V300-T305 HydrophobicContact CG1-CG2 3.91Å; V300-T305 HydrophobicContact CG2-CG2 3.95Å; V300-I348 HydrophobicContact CG2-CD1 3.86Å; V300-I348 HydrophobicContact CG2-CG2 4.2Å; V300-L349 HydrophobicContact CG1-CD2 4Å; V300-L355 HydrophobicContact CB-CD1 4.06Å; V300-L355 HydrophobicContact CB-CG 4.27Å; V300-L355 HydrophobicContact CG2-CD1 4.44Å; V300-D363 PolarHBondContact N-O 3.01Å
301I90.8Very high84.8Confident29 Ų2947.8 Ų47.815%0.14926%0.259CS..EExtended strand (participates in β ladder)trans-117.696.8176.7-63167.1000108.8L28 Y29 F299 I303 N304 D363L28-I301 HydrophobicContact CB-CG2 3.7Å; L28-I301 HydrophobicContact CD1-CG2 4.38Å; L28-I301 HydrophobicContact CG-CG2 4.46Å; Y29-I301 HydrophobicContact CE1-CG2 4.38Å; F299-I301 HydrophobicContact CD2-CB 4.49Å; F299-I301 HydrophobicContact CD2-CD1 3.84Å; F299-I301 HydrophobicContact CD2-CG1 3.92Å; F299-I301 HydrophobicContact CE2-CD1 4.15Å; F299-I301 HydrophobicContact CE2-CG1 4.42Å; I301-I303 PolarHBondContact O-N 3.45Å; I301-I303 VanDerWaalsContact O-N 3.07Å; I301-N304 PolarHBondContact N-O 3.18Å; I301-N304 WeakPolarHBondContact O-CB 2.93Å; I301-N304 PolarHBondContact O-N 3.29Å; I301-D363 WeakPolarHBondContact CD1-OD2 3.44Å; I301-D363 HydrophobicContact CG1-CB 3.86Å; I301-D363 WeakPolarHBondContact CG1-OD2 3.42Å
302G87.1Confident87.1Confident3 Ų341.9 Ų41.93%0.03122%0.221CC..THydrogen-bonded Turntrans60.1-111.4-173.300000111.2Y354G302-Y354 WeakPolarHBondContact O-CD1 3.45Å; G302-Y354 WeakPolarHBondContact O-CE1 3.43Å
303I83.4Confident89.1Confident136 Ų13641 Ų4170%0.69721%0.21SC*.THydrogen-bonded Turntrans-96.7-12174.664.4170.2000113.4L31 I301L31-I303 HydrophobicContact CD1-CG2 4.35Å; I301-I303 PolarHBondContact O-N 3.45Å; I301-I303 VanDerWaalsContact O-N 3.07Å
304N87.9Confident90.8Very high95 Ų9531.6 Ų31.651%0.50817%0.167SC..EExtended strand (participates in β ladder)trans-84125.8-179.4-65.5-25.4000108.5I301I301-N304 PolarHBondContact N-O 3.18Å; I301-N304 WeakPolarHBondContact O-CB 2.93Å; I301-N304 PolarHBondContact O-N 3.29Å
305T90.4Very high91.9Very high49 Ų4929.4 Ų29.430%0.30116%0.156SC..EExtended strand (participates in β ladder)trans-140.7164.7179.768.10000109.7F299 V300 C345F299-T305 WeakPolarHBondContact O-CA 3.14Å; V300-T305 HydrophobicContact CB-CG2 4.17Å; V300-T305 HydrophobicContact CG1-CG2 3.91Å; V300-T305 HydrophobicContact CG2-CG2 3.95Å; T305-C345 HydrophobicContact CG2-CB 3.82Å; T305-C345 WeakPolarHBondContact CG2-SG 3.24Å
306G90Very high92.1Very high21 Ų2124.1 Ų24.122%0.21613%0.129CC..EExtended strand (participates in β ladder)trans169.5-169.6173.100000111V297 S298 F299V297-G306 CarbonylContact C-O 3.54Å; V297-G306 WeakPolarHBondContact CA-O 3.4Å; S298-G306 PolarHBondContact N-O 3.38Å; F299-G306 WeakPolarHBondContact CD1-O 3.21Å; F299-G306 VanDerWaalsContact CE1-C 3.49Å; F299-G306 VanDerWaalsContact CE1-CA 3.46Å; F299-G306 PolarHBondContact N-O 3.27Å
307W91.3Very high91.5Very high23 Ų2325.6 Ų25.69%0.08714%0.142CC..  trans-120.6112.5179.3-176.3-23000109T202 A203 Y286 C288 W296 D309 H310T202-W307 WeakPolarHBondContact CA-O 3.47Å; A203-W307 HydrophobicContact CB-CD2 4.43Å; Y286-W307 VanDerWaalsContact CB-CZ2 3.42Å; Y286-W307 HydrophobicContact CG-CZ2 4.39Å; C288-W307 WeakPolarHBondContact SG-CH2 3.32Å; C288-W307 WeakPolarHBondContact SG-CZ3 3.36Å; W296-W307 HydrophobicContact CB-CE3 4.09Å; W296-W307 HydrophobicContact CB-CZ3 3.98Å; W296-W307 HydrophobicContact CD2-CZ3 4.46Å; W296-W307 AromaticContact CE3-CH2 3.88Å; W296-W307 HydrophobicContact CE3-CH2 3.88Å; W296-W307 AromaticContact CE3-CZ3 3.64Å; W296-W307 HydrophobicContact CE3-CZ3 3.64Å; W296-W307 HydrophobicContact CZ3-CH2 4.45Å; W307-D309 PolarHBondContact NE1-O 3.43Å; W307-H310 AromaticContact CD1-CE1 3.58Å; W307-H310 AromaticContact CD1-NE2 3.75Å; W307-H310 AromaticContact NE1-CE1 3.32Å; W307-H310 PolarHBondContact NE1-CE1 3.42Å; W307-H310 VanDerWaalsContact NE1-CE1 3.32Å; W307-H310 AromaticContact NE1-ND1 3.51Å; W307-H310 AromaticContact NE1-NE2 3.87Å
308V95.5Very high90.3Very high4 Ų428.9 Ų28.92%0.02416%0.156CC..  trans-127.5-17.4179.4-64.50000113.9F199 N200 A201 Q229 S298 F299 H310F199-V308 PolarHBondContact N-O 3.11Å; N200-V308 PolarHBondContact N-O 3.45Å; A201-V308 WeakPolarHBondContact O-CA 3.38Å; Q229-V308 VanDerWaalsContact NE2-CG1 3.32Å; S298-V308 PolarHBondContact OG-N 3.07Å; F299-V308 HydrophobicContact CD1-CG1 4.29Å; F299-V308 HydrophobicContact CD1-CG2 3.71Å; F299-V308 HydrophobicContact CE1-CG1 3.89Å; F299-V308 HydrophobicContact CE1-CG2 4.15Å; V308-H310 PolarHBondContact O-CD2 2.98Å; V308-H310 VanDerWaalsContact O-CD2 3.29Å
309D97.4Very high88.6Confident1 Ų133.3 Ų33.31%0.00518%0.184CC..EExtended strand (participates in β ladder)trans-89.2131.6178.5-55.9-81000110.2G197 D198 S298 W307 H364 L367G197-D309 WeakPolarHBondContact O-CA 3.19Å; D198-D309 WeakPolarHBondContact CB-OD1 3.38Å; S298-D309 WeakPolarHBondContact CB-OD2 3.29Å; S298-D309 PolarHBondContact OG-N 3.07Å; S298-D309 VanDerWaalsContact OG-N 3.1Å; S298-D309 PolarHBondContact OG-OD2 2.7Å; W307-D309 PolarHBondContact NE1-O 3.43Å; D309-H364 IonicContact OD1-ND1 3.92Å; D309-H364 PolarHBondContact OD1-ND1 2.81Å; D309-H364 IonicContact OD2-CE1 3.65Å; D309-H364 IonicContact OD2-CG 3.79Å; D309-H364 IonicContact OD2-ND1 3.79Å; D309-H364 PolarHBondContact OD2-ND1 2.72Å; D309-L367 HydrophobicContact CB-CD1 3.8Å; D309-L367 HydrophobicContact CB-CG 4.22Å; D309-L367 WeakPolarHBondContact O-CD1 3.18Å
310H97.1Very high86.9Confident6 Ų634.3 Ų34.33%0.02819%0.192CC..EExtended strand (participates in β ladder)trans-132.1152.9-178.8-65.2-87.9000111.8C196 G197 F199 A201 Y208 W307 V308 F312C196-H310 WeakPolarHBondContact CA-O 3.48Å; G197-H310 PolarHBondContact N-O 3.07Å; G197-H310 VanDerWaalsContact N-O 3.1Å; G197-H310 PolarHBondContact O-N 2.91Å; F199-H310 HydrophobicContact CD2-CB 3.81Å; F199-H310 HydrophobicContact CE2-CB 4.09Å; F199-H310 HydrophobicContact CG-CB 4.46Å; A201-H310 PolarHBondContact O-NE2 2.88Å; Y208-H310 AromaticContact CD2-CE1 3.8Å; Y208-H310 AromaticContact CD2-ND1 3.69Å; Y208-H310 AromaticContact CE2-ND1 3.71Å; W307-H310 AromaticContact CD1-CE1 3.58Å; W307-H310 AromaticContact CD1-NE2 3.75Å; W307-H310 AromaticContact NE1-CE1 3.32Å; W307-H310 PolarHBondContact NE1-CE1 3.42Å; W307-H310 VanDerWaalsContact NE1-CE1 3.32Å; W307-H310 AromaticContact NE1-ND1 3.51Å; W307-H310 AromaticContact NE1-NE2 3.87Å; V308-H310 PolarHBondContact O-CD2 2.98Å; V308-H310 VanDerWaalsContact O-CD2 3.29Å; H310-F312 HydrophobicContact CB-CD2 4.23Å; H310-F312 HydrophobicContact CB-CE2 3.39Å; H310-F312 HydrophobicContact CB-CZ 3.72Å
311M98Very high85Confident3 Ų336.7 Ų36.72%0.01521%0.209CC..EExtended strand (participates in β ladder)trans-135126171.8-173.4-174.8-59.800109.1L11 I194 C196 V285 L367 A369 F371L11-M311 HydrophobicContact CD2-CE 3.41Å; L11-M311 VanDerWaalsContact CD2-CE 3.41Å; L11-M311 HydrophobicContact CD2-SD 3.94Å; I194-M311 HydrophobicContact CG2-CG 4.16Å; C196-M311 HydrophobicContact CB-CB 4.11Å; C196-M311 HydrophobicContact CB-CG 3.95Å; V285-M311 HydrophobicContact CB-CB 4.04Å; V285-M311 HydrophobicContact CB-CG 4.08Å; V285-M311 WeakPolarHBondContact CB-O 3.36Å; V285-M311 HydrophobicContact CB-SD 4.2Å; V285-M311 HydrophobicContact CG1-SD 4.06Å; V285-M311 HydrophobicContact CG2-CB 4.14Å; V285-M311 HydrophobicContact CG2-CG 3.67Å; V285-M311 HydrophobicContact CG2-SD 3.89Å; V285-M311 PolarHBondContact N-O 3.23Å; M311-L367 HydrophobicContact CE-CB 4.1Å; M311-L367 WeakPolarHBondContact CE-O 3.28Å; M311-A369 HydrophobicContact SD-CB 3.89Å; M311-F371 HydrophobicContact SD-CE2 4.01Å; M311-F371 HydrophobicContact SD-CZ 3.85Å
312F97.9Very high83.5Confident2 Ų241 Ų411%0.00923%0.227CC..EExtended strand (participates in β ladder)trans-126.4150.1179-54.6-85.3000109.5I194 L195 F199 Y208 L211 T212 F282 T283 P284 H310I194-F312 CarbonylContact C-O 3.45Å; I194-F312 WeakPolarHBondContact CA-O 3.27Å; L195-F312 PolarHBondContact N-O 2.97Å; L195-F312 PolarHBondContact O-N 2.85Å; F199-F312 HydrophobicContact CE1-CE2 4.41Å; F199-F312 HydrophobicContact CE2-CE2 4.35Å; F199-F312 HydrophobicContact CZ-CD2 4.37Å; F199-F312 HydrophobicContact CZ-CE2 4.16Å; Y208-F312 AromaticContact CD2-CE1 3.96Å; Y208-F312 HydrophobicContact CD2-CE1 3.96Å; Y208-F312 AromaticContact CD2-CZ 3.72Å; Y208-F312 HydrophobicContact CD2-CZ 3.72Å; Y208-F312 AromaticContact CE2-CE1 3.65Å; Y208-F312 HydrophobicContact CE2-CE1 3.65Å; Y208-F312 AromaticContact CE2-CZ 3.79Å; Y208-F312 HydrophobicContact CE2-CZ 3.79Å; L211-F312 HydrophobicContact CB-CZ 4.44Å; L211-F312 HydrophobicContact CD1-CD2 4.22Å; L211-F312 HydrophobicContact CD1-CE2 3.6Å; L211-F312 HydrophobicContact CD1-CZ 3.91Å; T212-F312 HydrophobicContact CG2-CD1 4.11Å; T212-F312 HydrophobicContact CG2-CE1 3.74Å; F282-F312 HydrophobicContact CB-CB 4.02Å; F282-F312 HydrophobicContact CB-CD1 4.45Å; F282-F312 HydrophobicContact CB-CG 4.5Å; F282-F312 HydrophobicContact CD1-CB 3.64Å; F282-F312 HydrophobicContact CE1-CB 4.36Å; F282-F312 HydrophobicContact CG-CB 3.99Å; T283-F312 WeakPolarHBondContact O-CA 3.48Å; P284-F312 HydrophobicContact CB-CD1 4.04Å; P284-F312 HydrophobicContact CB-CE1 4.08Å; H310-F312 HydrophobicContact CB-CD2 4.23Å; H310-F312 HydrophobicContact CB-CE2 3.39Å; H310-F312 HydrophobicContact CB-CZ 3.72Å
313Y97.8Very high82.2Confident30 Ų3048.9 Ų48.912%0.11826%0.257CS..EExtended strand (participates in β ladder)trans-133.4146170.673.3-76000111.5V193 F282 T283 V285 L334 C336 F371V193-Y313 CarbonylContact O-C 3.47Å; V193-Y313 WeakPolarHBondContact O-CA 3.46Å; F282-Y313 CarbonylContact C-O 3.59Å; F282-Y313 WeakPolarHBondContact CA-O 3.22Å; T283-Y313 HydrophobicContact CG2-CE1 3.79Å; T283-Y313 PolarHBondContact N-O 2.94Å; T283-Y313 WeakPolarHBondContact O-CD1 3.33Å; T283-Y313 PolarHBondContact O-N 3.49Å; V285-Y313 HydrophobicContact CG2-CD1 3.7Å; V285-Y313 HydrophobicContact CG2-CE1 4.32Å; Y313-L334 HydrophobicContact CD2-CD2 4.16Å; Y313-L334 HydrophobicContact CD2-CG 4.28Å; Y313-C336 HydrophobicContact CD1-CB 4.19Å; Y313-C336 HydrophobicContact CE1-CB 3.62Å; Y313-F371 HydrophobicContact CD1-CE1 4.03Å; Y313-F371 AromaticContact CG-CE1 3.9Å; Y313-F371 HydrophobicContact CG-CE1 3.9Å
314S96.2Very high81.1Confident8 Ų849 Ų496%0.05627%0.266CS..EExtended strand (participates in β ladder)trans-117.8115173.3167.40000108P192 V193 K281 S316P192-S314 WeakPolarHBondContact CA-O 3.1Å; V193-S314 PolarHBondContact N-O 2.9Å; V193-S314 PolarHBondContact O-N 3.34Å; K281-S314 PolarHBondContact N-OG 3.39Å; K281-S314 WeakPolarHBondContact O-CA 3.32Å; S314-S316 VanDerWaalsContact C-N 3.32Å; S314-S316 PolarHBondContact O-N 3.45Å
315P91.2Very high80.1Confident8 Ų853.7 Ų53.75%0.05229%0.285CS..  trans-71.3-18.2-161.124.4-35.2000115.8E332 K333 L334P315-E332 HydrophobicContact CB-CB 3.86Å; P315-E332 HydrophobicContact CB-CG 3.88Å; P315-E332 HydrophobicContact CG-CG 4.09Å; P315-K333 WeakPolarHBondContact O-CB 3.29Å; P315-K333 PolarHBondContact O-N 2.92Å; P315-L334 WeakPolarHBondContact CB-O 3.31Å; P315-L334 PolarHBondContact O-N 3.18Å
316S84Confident78.5Confident21 Ų2152.2 Ų52.215%0.14728%0.28CS..  trans57.2126.6-159.8-171.20000112.6F190 S314 E332 K333F190-S316 WeakPolarHBondContact O-CB 3.26Å; F190-S316 PolarHBondContact O-OG 3.43Å; S314-S316 VanDerWaalsContact C-N 3.32Å; S314-S316 PolarHBondContact O-N 3.45Å; S316-E332 WeakPolarHBondContact O-CA 3.4Å; S316-K333 PolarHBondContact O-N 3.13Å; S316-K333 VanDerWaalsContact O-N 3.15Å
317V73.5Confident76.9Confident67 Ų6756.8 Ų56.841%0.40631%0.306SS..EExtended strand (participates in β ladder)trans-105.9122.8-178.2169.40000109.2I330V317-I330 HydrophobicContact CB-CG2 4.41Å; V317-I330 HydrophobicContact CG1-CB 4.23Å; V317-I330 HydrophobicContact CG1-CG1 4.06Å; V317-I330 HydrophobicContact CG1-CG2 3.42Å; V317-I330 VanDerWaalsContact CG1-CG2 3.42Å; V317-I330 HydrophobicContact CG2-CG2 4.25Å
318K65.2Low75.5Confident69 Ų6961.8 Ų61.830%0.333%0.33SS..EExtended strand (participates in β ladder)trans-105.4137.4166-83.4-168.6170.3-1780110.3D146 I330 V331 K333D146-K318 PolarHBondContact O-NZ 2.76Å; K318-I330 WeakPolarHBondContact O-CA 3.41Å; K318-V331 PolarHBondContact N-O 2.98Å; K318-V331 PolarHBondContact O-N 3.46Å; K318-K333 VanDerWaalsContact CD-CE 3.5Å
319T58.5Low74Confident94 Ų9463.7 Ų63.758%0.57734%0.343SS*.EExtended strand (participates in β ladder)trans-92.9109.6172-54.70000108.3H328T319-H328 HydrophobicContact CG2-CB 3.37Å
320V58.2Low72.6Confident51 Ų5169.4 Ų69.431%0.30937%0.373SS..EExtended strand (participates in β ladder)trans-105.9129.9-179.8-175.60000109.1F322 H328 S329 V331V320-F322 HydrophobicContact CG1-CE1 4.34Å; V320-F322 HydrophobicContact CG1-CZ 4.33Å; V320-H328 WeakPolarHBondContact O-CA 3.29Å; V320-S329 PolarHBondContact N-O 3.07Å; V320-S329 PolarHBondContact O-N 3.47Å; V320-V331 HydrophobicContact CB-CG2 4.36Å; V320-V331 HydrophobicContact CG2-CB 4.34Å; V320-V331 HydrophobicContact CG2-CG2 3.81Å
321S53.3Low71.4Confident51 Ų5170.9 Ų70.936%0.35738%0.382SS..EExtended strand (participates in β ladder)trans-99.4117.6169.8-165.10000109.9Y323S321-Y323 PolarHBondContact OG-O 3.22Å
322F60.6Low70.8Confident119 Ų11973.9 Ų73.952%0.52240%0.396SS..SBendtrans-81.3-21.7176.4-69.1-73.3000112.7V320 S329V320-F322 HydrophobicContact CG1-CE1 4.34Å; V320-F322 HydrophobicContact CG1-CZ 4.33Å; F322-S329 WeakPolarHBondContact CE2-OG 3.44Å
323Y59.2Low70.3Confident169 Ų16974.4 Ų74.466%0.66340%0.398SS*.SBendtrans-138142.9178.8-57.5-79.3000109.5S321 Q325 G326S321-Y323 PolarHBondContact OG-O 3.22Å; Y323-Q325 PolarHBondContact O-N 3.21Å; Y323-G326 PolarHBondContact O-N 2.78Å
324P60.4Low70.1Confident138 Ų13873 Ų7390%0.89639%0.392SS*.THydrogen-bonded Turntrans-52.5-26.5-176.9-25.732.2000115.1
325Q65.5Low70Confident194 Ų19477.4 Ų77.491%0.90741%0.408SS*.THydrogen-bonded Turntrans-123.411.9-178.4-64.1-90.91.100112.2Y323Y323-Q325 PolarHBondContact O-N 3.21Å
326G57.3Low70.2Confident18 Ų1878.6 Ų78.619%0.18642%0.416CS..SBendtrans-89.5163.2-177.200000112.8Y323 H328Y323-G326 PolarHBondContact O-N 2.78Å; G326-H328 PolarHBondContact O-N 3.21Å
327P57.4Low70.8Confident117 Ų11782.5 Ų82.576%0.7643%0.431SS*.PPolyproline II helixtrans-60.3134.6174.425.6-32.6000110.2S329P327-S329 PolarHBondContact O-N 3.21Å
328H62Low71.8Confident127 Ų12787 Ų8759%0.58844%0.44SS*.EExtended strand (participates in β ladder)trans-67.4132.8173.3-66-70.9000110.5T319 V320 G326T319-H328 HydrophobicContact CG2-CB 3.37Å; V320-H328 WeakPolarHBondContact O-CA 3.29Å; G326-H328 PolarHBondContact O-N 3.21Å
329S62.4Low73.2Confident45 Ų4588.4 Ų88.432%0.31544%0.444SS..EExtended strand (participates in β ladder)trans-97.8135173.1-62.90000110.2V320 F322 P327V320-S329 PolarHBondContact N-O 3.07Å; V320-S329 PolarHBondContact O-N 3.47Å; F322-S329 WeakPolarHBondContact CE2-OG 3.44Å; P327-S329 PolarHBondContact O-N 3.21Å
330I68.2Low74.9Confident121 Ų12187.9 Ų87.962%0.62144%0.437SS*.EExtended strand (participates in β ladder)trans-86.8119.7173.7-75.3164.9000108.1V317 K318V317-I330 HydrophobicContact CB-CG2 4.41Å; V317-I330 HydrophobicContact CG1-CB 4.23Å; V317-I330 HydrophobicContact CG1-CG1 4.06Å; V317-I330 HydrophobicContact CG1-CG2 3.42Å; V317-I330 VanDerWaalsContact CG1-CG2 3.42Å; V317-I330 HydrophobicContact CG2-CG2 4.25Å; K318-I330 WeakPolarHBondContact O-CA 3.41Å
331V73.4Confident76.4Confident36 Ų3691.7 Ų91.722%0.21845%0.451CS..EExtended strand (participates in β ladder)trans-110.8125.1175-175.60000108.8K318 V320 V374K318-V331 PolarHBondContact N-O 2.98Å; K318-V331 PolarHBondContact O-N 3.46Å; V320-V331 HydrophobicContact CB-CG2 4.36Å; V320-V331 HydrophobicContact CG2-CB 4.34Å; V320-V331 HydrophobicContact CG2-CG2 3.81Å; V331-V374 HydrophobicContact CG1-CG1 4.14Å
332E84.9Confident78.1Confident66 Ų6689.4 Ų89.431%0.30844%0.435SS..EExtended strand (participates in β ladder)trans-84.4128.3170.8-71.9175.6156.800109.4P315 S316 L334 R335P315-E332 HydrophobicContact CB-CB 3.86Å; P315-E332 HydrophobicContact CB-CG 3.88Å; P315-E332 HydrophobicContact CG-CG 4.09Å; S316-E332 WeakPolarHBondContact O-CA 3.4Å; E332-L334 VanDerWaalsContact C-N 3.33Å; E332-R335 HydrophobicContact CB-CG 4.32Å; E332-R335 IonicContact OE2-NE 3.2Å; E332-R335 PolarHBondContact OE2-NE 3.27Å; E332-R335 IonicContact OE2-NH2 3.98Å
333K87.8Confident79.4Confident13 Ų1386.1 Ų86.16%0.05742%0.423CS..SBendtrans-80.1-14.4179.5-79.1-166.3165.3-163.40114P192 P315 S316 K318 F373 V374P192-K333 HydrophobicContact CG-CB 3.56Å; P192-K333 HydrophobicContact CG-CD 4.23Å; P315-K333 WeakPolarHBondContact O-CB 3.29Å; P315-K333 PolarHBondContact O-N 2.92Å; S316-K333 PolarHBondContact O-N 3.13Å; S316-K333 VanDerWaalsContact O-N 3.15Å; K318-K333 VanDerWaalsContact CD-CE 3.5Å; K333-F373 CarbonylContact O-C 3.47Å; K333-F373 WeakPolarHBondContact O-CA 3.37Å; K333-V374 PolarHBondContact O-N 2.7Å
334L93.3Very high80.8Confident0 Ų078.8 Ų78.80%040%0.396CS..EExtended strand (participates in β ladder)trans-142.2133.6-178.9178.474.3000109.8F9 I151 P192 I194 Y313 P315 E332 F371 E372F9-L334 HydrophobicContact CE1-CD1 3.89Å; F9-L334 HydrophobicContact CZ-CD1 3.89Å; I151-L334 HydrophobicContact CD1-CD1 3.94Å; I151-L334 HydrophobicContact CD1-CD2 3.96Å; P192-L334 HydrophobicContact CB-CB 3.7Å; P192-L334 HydrophobicContact CB-CD2 3.93Å; P192-L334 HydrophobicContact CB-CG 4.4Å; P192-L334 HydrophobicContact CG-CB 4.25Å; I194-L334 HydrophobicContact CD1-CD2 4.17Å; I194-L334 HydrophobicContact CG1-CD2 3.77Å; Y313-L334 HydrophobicContact CD2-CD2 4.16Å; Y313-L334 HydrophobicContact CD2-CG 4.28Å; P315-L334 WeakPolarHBondContact CB-O 3.31Å; P315-L334 PolarHBondContact O-N 3.18Å; E332-L334 VanDerWaalsContact C-N 3.33Å; L334-F371 HydrophobicContact CD1-CB 3.8Å; L334-F371 HydrophobicContact CD1-CD1 4.05Å; L334-F371 HydrophobicContact CD1-CG 4.22Å; L334-F371 HydrophobicContact CD2-CD1 4.49Å; L334-F371 HydrophobicContact CG-CD1 4.2Å; L334-E372 WeakPolarHBondContact CA-O 3.45Å
335R94.1Very high82.2Confident101 Ų10173.6 Ų73.638%0.38136%0.363SS..EExtended strand (participates in β ladder)trans-137137.4177.6-65.7178.7174.1159.11110.2E332 F371 E372E332-R335 HydrophobicContact CB-CG 4.32Å; E332-R335 IonicContact OE2-NE 3.2Å; E332-R335 PolarHBondContact OE2-NE 3.27Å; E332-R335 IonicContact OE2-NH2 3.98Å; R335-F371 CarbonylContact O-C 3.54Å; R335-F371 WeakPolarHBondContact O-CA 3.35Å; R335-E372 PolarHBondContact N-O 3.25Å; R335-E372 PolarHBondContact O-N 3.3Å
336C95.6Very high83.3Confident33 Ų3367.7 Ų67.722%0.22334%0.343CS..EExtended strand (participates in β ladder)trans-79.1127.1167.1-179.90000109.1Y313 F371Y313-C336 HydrophobicContact CD1-CB 4.19Å; Y313-C336 HydrophobicContact CE1-CB 3.62Å; C336-F371 HydrophobicContact CB-CD1 4.05Å; C336-F371 HydrophobicContact CB-CE1 3.87Å
337K95.1Very high84.9Confident104 Ų10469.2 Ų69.245%0.45235%0.345SS..EExtended strand (participates in β ladder)trans-99.7-43.8-175.9-65-59.2-64.6-135.30113E370 E372K337-E370 PolarHBondContact N-O 3.32Å; K337-E372 HydrophobicContact CD-CB 4.19Å; K337-E372 HydrophobicContact CD-CG 3.95Å; K337-E372 VanDerWaalsContact CD-OE2 3.31Å; K337-E372 WeakPolarHBondContact CD-OE2 3.2Å; K337-E372 WeakPolarHBondContact CE-OE1 3.42Å; K337-E372 HydrophobicContact CG-CB 3.99Å; K337-E372 HydrophobicContact CG-CG 3.63Å; K337-E372 IonicContact NZ-OE1 2.89Å; K337-E372 PolarHBondContact NZ-OE1 3.42Å; K337-E372 IonicContact NZ-OE2 2.84Å; K337-E372 PolarHBondContact NZ-OE2 2.82Å
338R95.3Very high86.5Confident162 Ų16264 Ų6461%0.61131%0.311SS*.EExtended strand (participates in β ladder)trans-156.5157.9178.253.1-179.9172.1155.14.7109A369 E370R338-A369 WeakPolarHBondContact O-CA 3.31Å; R338-E370 HydrophobicContact CG-CB 3.73Å; R338-E370 IonicContact CZ-OE1 3.92Å; R338-E370 IonicContact CZ-OE2 3.02Å; R338-E370 VanDerWaalsContact NE-CD 3.26Å; R338-E370 IonicContact NE-OE1 3.95Å; R338-E370 PolarHBondContact NE-OE1 3.2Å; R338-E370 IonicContact NE-OE2 2.83Å; R338-E370 PolarHBondContact NE-OE2 2.96Å; R338-E370 IonicContact NH2-OE1 3.5Å; R338-E370 PolarHBondContact NH2-OE1 2.84Å; R338-E370 IonicContact NH2-OE2 3.66Å; R338-E370 PolarHBondContact NH2-OE2 3.45Å; R338-E370 PolarHBondContact O-N 3.11Å
339R94.8Very high87.8Confident98 Ų9860.1 Ų60.137%0.3729%0.294SS..EExtended strand (participates in β ladder)trans-132.1151.1176.266.2-162.6-174.7-148.91.7108.5V285 Y286 L368 A369V285-R339 HydrophobicContact CG1-CB 4.22Å; V285-R339 WeakPolarHBondContact O-CD 3.44Å; V285-R339 PolarHBondContact O-NE 3.19Å; V285-R339 PolarHBondContact O-NH1 3.3Å; Y286-R339 HydrophobicContact CD1-CG 4.37Å; Y286-R339 HydrophobicContact CE1-CB 4.14Å; Y286-R339 HydrophobicContact CE1-CG 4.06Å; Y286-R339 HydrophobicContact CE2-CB 4.34Å; R339-L368 CarbonylContact C-O 3.49Å; R339-L368 WeakPolarHBondContact CA-O 3.17Å; R339-A369 HydrophobicContact CB-CB 4.26Å
340L93.9Very high89.2Confident82 Ų8264.6 Ų64.643%0.42932%0.315SS..PPolyproline II helixtrans-64.9136.6169.4-176.763.5000108Y286 L368Y286-L340 VanDerWaalsContact CE1-O 3.24Å; Y286-L340 WeakPolarHBondContact CE1-O 3.41Å; Y286-L340 PolarHBondContact OH-O 3.49Å; L340-L368 HydrophobicContact CB-CB 3.91Å; L340-L368 HydrophobicContact CD2-CB 4.24Å; L340-L368 PolarHBondContact N-O 2.88Å
341E90.1Very high90.2Very high131 Ų13166.6 Ų66.661%0.61231%0.314SS*.PPolyproline II helixtrans-72.5137.3179-173.5169.7-160.100110.2
342L89.2Confident91Very high3 Ų367.1 Ų67.12%0.01632%0.317CS..PPolyproline II helixtrans-85.2152.6172.4-67.3-179.9000110.3Y286 W296 I365 L367Y286-L342 HydrophobicContact CD1-CD1 3.85Å; Y286-L342 HydrophobicContact CD1-CG 4.04Å; Y286-L342 HydrophobicContact CE1-CD1 4.06Å; Y286-L342 HydrophobicContact CE1-CD2 4.35Å; Y286-L342 HydrophobicContact CE1-CG 3.8Å; W296-L342 HydrophobicContact CB-CB 3.83Å; W296-L342 HydrophobicContact CB-CD1 4.2Å; W296-L342 HydrophobicContact CD2-CB 4.1Å; W296-L342 HydrophobicContact CG-CB 3.66Å; W296-L342 PolarHBondContact NE1-O 3.33Å; W296-L342 VanDerWaalsContact NE1-O 3.09Å; L342-I365 HydrophobicContact CD2-CG2 3.99Å; L342-L367 HydrophobicContact CD1-CD2 3.92Å; L342-L367 HydrophobicContact CD2-CD2 3.7Å; L342-L367 HydrophobicContact CG-CD2 4.31Å
343L88.2Confident91.3Very high51 Ų5165 Ų6527%0.26731%0.313SS..PPolyproline II helixtrans-103.1156.1178.9-61179000109.8V297 E347 I348V297-L343 PolarHBondContact N-O 3.16Å; L343-E347 HydrophobicContact CB-CB 4.17Å; L343-I348 HydrophobicContact CB-CD1 4.23Å; L343-I348 HydrophobicContact CB-CG1 3.78Å; L343-I348 HydrophobicContact CD1-CG1 4.23Å
344S88.7Confident91.6Very high14 Ų1468.8 Ų68.810%0.09833%0.328CS..BIsolated β-bridgetrans-71.8159.6164.763.90000111.8D295 S346 E347 I348D295-S344 WeakPolarHBondContact O-CA 3.43Å; S344-S346 PolarHBondContact O-N 3.08Å; S344-S346 PolarHBondContact OG-OG 3.42Å; S344-S346 VanDerWaalsContact OG-OG 3.1Å; S344-E347 PolarHBondContact N-OE2 3.22Å; S344-E347 PolarHBondContact O-N 2.94Å; S344-E347 VanDerWaalsContact O-N 3.16Å; S344-E347 VanDerWaalsContact OG-CG 3.28Å; S344-E347 WeakPolarHBondContact OG-CG 3.24Å; S344-E347 PolarHBondContact OG-N 3.08Å; S344-E347 PolarHBondContact OG-OE2 3.14Å; S344-I348 WeakPolarHBondContact O-CG1 3.31Å; S344-I348 PolarHBondContact O-N 3.3Å
345C88.9Confident91.7Very high29 Ų2968.8 Ų68.820%0.19633%0.328CS..Hα-helixtrans-50-46.2169.5170.70000112.1V297 T305 E347 I348 L349V297-C345 HydrophobicContact CG1-CB 4.16Å; T305-C345 HydrophobicContact CG2-CB 3.82Å; T305-C345 WeakPolarHBondContact CG2-SG 3.24Å; C345-E347 VanDerWaalsContact C-N 3.31Å; C345-E347 PolarHBondContact O-N 3.42Å; C345-I348 PolarHBondContact O-N 3.09Å; C345-L349 WeakPolarHBondContact O-CB 2.95Å; C345-L349 WeakPolarHBondContact O-CG 3.39Å; C345-L349 PolarHBondContact O-N 2.83Å; C345-L349 VanDerWaalsContact SG-CD1 3.57Å
346S89.1Confident91.7Very high71 Ų7164 Ų6450%0.49731%0.31SS..Hα-helixtrans-62.1-39.5-177.974.80000112.3S344 N350S344-S346 PolarHBondContact O-N 3.08Å; S344-S346 PolarHBondContact OG-OG 3.42Å; S344-S346 VanDerWaalsContact OG-OG 3.1Å; S346-N350 WeakPolarHBondContact O-CB 3.37Å; S346-N350 PolarHBondContact O-N 3.08Å; S346-N350 PolarHBondContact O-ND2 2.76Å
347E90.2Very high91.7Very high50 Ų5062.8 Ų62.823%0.23430%0.301CS..Hα-helixtrans-69-40.8177.2-70.9173.4107.100112.2L343 S344 C345 N350 R351L343-E347 HydrophobicContact CB-CB 4.17Å; S344-E347 PolarHBondContact N-OE2 3.22Å; S344-E347 PolarHBondContact O-N 2.94Å; S344-E347 VanDerWaalsContact O-N 3.16Å; S344-E347 VanDerWaalsContact OG-CG 3.28Å; S344-E347 WeakPolarHBondContact OG-CG 3.24Å; S344-E347 PolarHBondContact OG-N 3.08Å; S344-E347 PolarHBondContact OG-OE2 3.14Å; C345-E347 VanDerWaalsContact C-N 3.31Å; C345-E347 PolarHBondContact O-N 3.42Å; E347-N350 PolarHBondContact O-N 3.14Å; E347-R351 VanDerWaalsContact O-CB 3.23Å; E347-R351 WeakPolarHBondContact O-CB 3.41Å; E347-R351 WeakPolarHBondContact O-CG 3.24Å; E347-R351 PolarHBondContact O-N 3.14Å; E347-R351 IonicContact OE1-NH2 3.59Å; E347-R351 PolarHBondContact OE1-NH2 2.96Å
348I90.3Very high91.6Very high6 Ų660.9 Ų60.93%0.03131%0.305CS..Hα-helixtrans-61.7-53.5176.7-66.2166.3000109.5V297 V300 L343 S344 C345 N350 R351 V352 G353 L355 I365V297-I348 HydrophobicContact CG2-CD1 3.41Å; V297-I348 VanDerWaalsContact CG2-CD1 3.41Å; V300-I348 HydrophobicContact CG2-CD1 3.86Å; V300-I348 HydrophobicContact CG2-CG2 4.2Å; L343-I348 HydrophobicContact CB-CD1 4.23Å; L343-I348 HydrophobicContact CB-CG1 3.78Å; L343-I348 HydrophobicContact CD1-CG1 4.23Å; S344-I348 WeakPolarHBondContact O-CG1 3.31Å; S344-I348 PolarHBondContact O-N 3.3Å; C345-I348 PolarHBondContact O-N 3.09Å; I348-N350 VanDerWaalsContact C-N 3.29Å; I348-N350 PolarHBondContact O-N 3.34Å; I348-R351 PolarHBondContact O-N 3.48Å; I348-V352 HydrophobicContact CG2-CG2 3.85Å; I348-V352 VanDerWaalsContact O-CG2 3.31Å; I348-V352 WeakPolarHBondContact O-CG2 3.41Å; I348-V352 PolarHBondContact O-N 3.08Å; I348-G353 PolarHBondContact O-N 3.12Å; I348-L355 HydrophobicContact CG2-CD1 4.12Å; I348-L355 HydrophobicContact CG2-CD2 4.28Å; I348-L355 HydrophobicContact CG2-CG 4.24Å; I348-I365 HydrophobicContact CD1-CD1 3.99Å; I348-I365 HydrophobicContact CD1-CG1 4.02Å
349L90.2Very high91.4Very high47 Ų4759.1 Ų59.125%0.24630%0.304CS..Hα-helixtrans-61.5-37.1-178.8-67.1-179.1000112.3V300 C345 G353 Y354V300-L349 HydrophobicContact CG1-CD2 4Å; C345-L349 WeakPolarHBondContact O-CB 2.95Å; C345-L349 WeakPolarHBondContact O-CG 3.39Å; C345-L349 PolarHBondContact O-N 2.83Å; C345-L349 VanDerWaalsContact SG-CD1 3.57Å; L349-G353 VanDerWaalsContact O-CA 3.25Å; L349-G353 WeakPolarHBondContact O-CA 3.23Å; L349-G353 PolarHBondContact O-N 2.85Å; L349-G353 VanDerWaalsContact O-N 3.16Å; L349-Y354 HydrophobicContact CD1-CE1 4.33Å; L349-Y354 HydrophobicContact CD2-CD1 3.51Å; L349-Y354 HydrophobicContact CD2-CE1 3.74Å; L349-Y354 HydrophobicContact CD2-CG 4.13Å
350N90.9Very high91.4Very high139 Ų13955.7 Ų55.774%0.74329%0.294SS*.Hα-helixtrans-74.4-31.8178.3-72.6-27.3000113.4S346 E347 I348S346-N350 WeakPolarHBondContact O-CB 3.37Å; S346-N350 PolarHBondContact O-N 3.08Å; S346-N350 PolarHBondContact O-ND2 2.76Å; E347-N350 PolarHBondContact O-N 3.14Å; I348-N350 VanDerWaalsContact C-N 3.29Å; I348-N350 PolarHBondContact O-N 3.34Å
351R89.9Confident91.4Very high163 Ų16351.8 Ų51.862%0.61527%0.274SS*.Hα-helixtrans-87.7-44.8-176.6-70.5178.3-169.9-161.912.1112.8E347 I348E347-R351 VanDerWaalsContact O-CB 3.23Å; E347-R351 WeakPolarHBondContact O-CB 3.41Å; E347-R351 WeakPolarHBondContact O-CG 3.24Å; E347-R351 PolarHBondContact O-N 3.14Å; E347-R351 IonicContact OE1-NH2 3.59Å; E347-R351 PolarHBondContact OE1-NH2 2.96Å; I348-R351 PolarHBondContact O-N 3.48Å
352V89.5Confident91.8Very high46 Ų4645.5 Ų45.528%0.27925%0.245SC..THydrogen-bonded Turntrans-124.7-16.6-171.5-54.80000113.5I348 L355 N357I348-V352 HydrophobicContact CG2-CG2 3.85Å; I348-V352 VanDerWaalsContact O-CG2 3.31Å; I348-V352 WeakPolarHBondContact O-CG2 3.41Å; I348-V352 PolarHBondContact O-N 3.08Å; V352-L355 HydrophobicContact CG2-CD2 3.94Å; V352-N357 PolarHBondContact O-ND2 3.26Å; V352-N357 VanDerWaalsContact O-ND2 3.1Å
353G91.8Very high92.1Very high22 Ų2245.5 Ų45.523%0.22724%0.244CC..  trans88.7-163.5-178.500000113.1I348 L349I348-G353 PolarHBondContact O-N 3.12Å; L349-G353 VanDerWaalsContact O-CA 3.25Å; L349-G353 WeakPolarHBondContact O-CA 3.23Å; L349-G353 PolarHBondContact O-N 2.85Å; L349-G353 VanDerWaalsContact O-N 3.16Å
354Y93.8Very high92.5Very high92 Ų9243.7 Ų43.736%0.36124%0.235SC..SBendtrans-65.7152177.3-61.4-74.1000111.4L31 G302 L349 N357L31-Y354 HydrophobicContact CB-CD1 4.06Å; L31-Y354 HydrophobicContact CB-CD2 3.82Å; L31-Y354 HydrophobicContact CB-CE1 4.3Å; L31-Y354 HydrophobicContact CB-CE2 4.08Å; L31-Y354 HydrophobicContact CB-CG 3.82Å; L31-Y354 HydrophobicContact CD1-CD1 3.99Å; L31-Y354 HydrophobicContact CD1-CE1 3.53Å; L31-Y354 HydrophobicContact CD1-CE2 4.29Å; G302-Y354 WeakPolarHBondContact O-CD1 3.45Å; G302-Y354 WeakPolarHBondContact O-CE1 3.43Å; L349-Y354 HydrophobicContact CD1-CE1 4.33Å; L349-Y354 HydrophobicContact CD2-CD1 3.51Å; L349-Y354 HydrophobicContact CD2-CE1 3.74Å; L349-Y354 HydrophobicContact CD2-CG 4.13Å; Y354-N357 WeakPolarHBondContact O-CB 3.3Å; Y354-N357 PolarHBondContact O-ND2 3.19Å
355L95.3Very high92.9Very high0 Ų044.5 Ų44.50%024%0.238CC..SBendtrans-113.2148.2-178.9-51.2-174.2000111.1C32 V300 I348 V352 N357 C360 D363 I365C32-L355 VanDerWaalsContact SG-C 3.52Å; C32-L355 PolarHBondContact SG-O 3.25Å; V300-L355 HydrophobicContact CB-CD1 4.06Å; V300-L355 HydrophobicContact CB-CG 4.27Å; V300-L355 HydrophobicContact CG2-CD1 4.44Å; I348-L355 HydrophobicContact CG2-CD1 4.12Å; I348-L355 HydrophobicContact CG2-CD2 4.28Å; I348-L355 HydrophobicContact CG2-CG 4.24Å; V352-L355 HydrophobicContact CG2-CD2 3.94Å; L355-N357 VanDerWaalsContact CD2-ND2 3.3Å; L355-N357 WeakPolarHBondContact CD2-ND2 3.44Å; L355-C360 HydrophobicContact CD2-CB 3.85Å; L355-D363 HydrophobicContact CB-CB 4.31Å; L355-I365 HydrophobicContact CD1-CD1 3.74Å
356P95.6Very high93.2Very high0 Ų043.9 Ų43.90%023%0.233CC..SBendcis-74.8157.1-7.328.6-28.4000112L17 M22 I37 C360L17-P356 HydrophobicContact CD2-CG 4.32Å; M22-P356 HydrophobicContact SD-CG 4.15Å; I37-P356 HydrophobicContact CB-CG 4.48Å; I37-P356 HydrophobicContact CG2-CG 3.93Å; P356-C360 CarbonylContact C-O 3.44Å; P356-C360 WeakPolarHBondContact CA-O 3.38Å; P356-C360 WeakPolarHBondContact CB-O 3.08Å
357N94.6Very high93.7Very high9 Ų940.5 Ų40.55%0.04821%0.21CC..  trans-145-169.5-179.263.444.7000112E36 V352 Y354 L355 Q359 C360E36-N357 WeakPolarHBondContact OE2-CA 3.48Å; E36-N357 WeakPolarHBondContact OE2-CB 3.32Å; V352-N357 PolarHBondContact O-ND2 3.26Å; V352-N357 VanDerWaalsContact O-ND2 3.1Å; Y354-N357 WeakPolarHBondContact O-CB 3.3Å; Y354-N357 PolarHBondContact O-ND2 3.19Å; L355-N357 VanDerWaalsContact CD2-ND2 3.3Å; L355-N357 WeakPolarHBondContact CD2-ND2 3.44Å; N357-Q359 PolarHBondContact O-N 3.44Å; N357-Q359 WeakPolarHBondContact OD1-CA 3.28Å; N357-Q359 PolarHBondContact OD1-N 3.46Å; N357-C360 PolarHBondContact N-O 3.46Å; N357-C360 VanDerWaalsContact O-O 3.05Å; N357-C360 PolarHBondContact OD1-N 2.99Å
358A92.3Very high94Very high64 Ų6439.5 Ų39.553%0.52921%0.206SC..SBendtrans-63.1-20.4-17900000115.3E36E36-A358 HydrophobicContact CG-CB 4.4Å; E36-A358 PolarHBondContact OE2-N 2.79Å
359Q91.4Very high94.4Very high125 Ų12539.3 Ų39.358%0.58421%0.205SC*.SBendtrans-101.9-35.3-179.7-61.7-178.510.700112.6N357N357-Q359 PolarHBondContact O-N 3.44Å; N357-Q359 WeakPolarHBondContact OD1-CA 3.28Å; N357-Q359 PolarHBondContact OD1-N 3.46Å
360C94.5Very high94.8Very high25 Ų2539 Ų3917%0.16920%0.203CC..  trans-119.7113.5-176.9-63.70000109.6E49 L355 P356 N357 S362E49-C360 WeakPolarHBondContact OE1-CA 3.17Å; L355-C360 HydrophobicContact CD2-CB 3.85Å; P356-C360 CarbonylContact C-O 3.44Å; P356-C360 WeakPolarHBondContact CA-O 3.38Å; P356-C360 WeakPolarHBondContact CB-O 3.08Å; N357-C360 PolarHBondContact N-O 3.46Å; N357-C360 VanDerWaalsContact O-O 3.05Å; N357-C360 PolarHBondContact OD1-N 2.99Å; C360-S362 VanDerWaalsContact C-N 3.28Å; C360-S362 PolarHBondContact O-N 3.17Å
361G95.7Very high95.1Very high0 Ų032.4 Ų32.40%017%0.167CC..SBendtrans-82-4.2-176.200000114.6R42 E49R42-G361 VanDerWaalsContact CZ-O 3.29Å; R42-G361 PolarHBondContact NE-O 2.89Å; R42-G361 PolarHBondContact NH2-O 2.95Å; E49-G361 PolarHBondContact OE1-N 2.7Å
362S97.1Very high95.3Very high0 Ų026.8 Ų26.80%015%0.148CC..SBendtrans-121.8161.5173-164.60000111Y14 N15 C360 H364Y14-S362 VanDerWaalsContact CE2-CB 3.49Å; Y14-S362 VanDerWaalsContact OH-CB 3.27Å; Y14-S362 WeakPolarHBondContact OH-CB 3.43Å; N15-S362 WeakPolarHBondContact O-CB 3.19Å; N15-S362 PolarHBondContact O-OG 2.88Å; C360-S362 VanDerWaalsContact C-N 3.28Å; C360-S362 PolarHBondContact O-N 3.17Å; S362-H364 PolarHBondContact OG-N 3.31Å
363D96.4Very high95.3Very high2 Ų224.6 Ų24.61%0.01114%0.135CC..SBendtrans-84.8-10.7166.656.9-10.9000113.2L17 Y29 F299 V300 I301 L355L17-D363 WeakPolarHBondContact CB-OD1 3.19Å; L17-D363 HydrophobicContact CD2-CB 4.41Å; Y29-D363 HydrophobicContact CE1-CB 4.19Å; Y29-D363 PolarHBondContact OH-OD2 2.91Å; F299-D363 CarbonylContact C-O 3.58Å; F299-D363 VanDerWaalsContact CA-O 3.27Å; F299-D363 WeakPolarHBondContact CA-O 3.44Å; V300-D363 PolarHBondContact N-O 3.01Å; I301-D363 WeakPolarHBondContact CD1-OD2 3.44Å; I301-D363 HydrophobicContact CG1-CB 3.86Å; I301-D363 WeakPolarHBondContact CG1-OD2 3.42Å; L355-D363 HydrophobicContact CB-CB 4.31Å
364H97Very high94.9Very high13 Ų1324.7 Ų24.76%0.0613%0.13CC..BIsolated β-bridgetrans-91161.9169.3-71.2-109.8000112.5Y14 N15 D198 S298 D309 S362Y14-H364 HydrophobicContact CE2-CB 4.39Å; Y14-H364 VanDerWaalsContact CE2-O 3.31Å; Y14-H364 WeakPolarHBondContact CE2-O 3.4Å; N15-H364 HydrophobicContact CB-CB 3.97Å; N15-H364 PolarHBondContact ND2-NE2 2.76Å; D198-H364 IonicContact OD2-CE1 3.77Å; D198-H364 PolarHBondContact OD2-CE1 3.31Å; D198-H364 IonicContact OD2-NE2 2.7Å; S298-H364 CarbonylContact O-C 3.5Å; S298-H364 VanDerWaalsContact O-CA 3.29Å; S298-H364 WeakPolarHBondContact O-CA 3.31Å; D309-H364 IonicContact OD1-ND1 3.92Å; D309-H364 PolarHBondContact OD1-ND1 2.81Å; D309-H364 IonicContact OD2-CE1 3.65Å; D309-H364 IonicContact OD2-CG 3.79Å; D309-H364 IonicContact OD2-ND1 3.79Å; D309-H364 PolarHBondContact OD2-ND1 2.72Å; S362-H364 PolarHBondContact OG-N 3.31Å
365I95.4Very high93.7Very high32 Ų3222.5 Ų22.516%0.16412%0.123CC..  trans-108.1132.9177.7-55.4-58.4000109.3S298 L342 I348 L355 L367S298-I365 PolarHBondContact O-N 2.95Å; L342-I365 HydrophobicContact CD2-CG2 3.99Å; I348-I365 HydrophobicContact CD1-CD1 3.99Å; I348-I365 HydrophobicContact CD1-CG1 4.02Å; L355-I365 HydrophobicContact CD1-CD1 3.74Å; I365-L367 PolarHBondContact O-N 3.39Å
366P97.3Very high93.6Very high16 Ų1623.6 Ų23.610%0.10413%0.13CC..  trans-66.3129.6178.725.9-34.3000112.1Y14 L53Y14-P366 HydrophobicContact CD1-CB 4.05Å; Y14-P366 HydrophobicContact CD2-CB 4.27Å; Y14-P366 HydrophobicContact CE1-CB 4.47Å; Y14-P366 HydrophobicContact CG-CB 3.95Å; L53-P366 HydrophobicContact CD1-CB 3.95Å; L53-P366 HydrophobicContact CD1-CG 4.03Å; L53-P366 HydrophobicContact CD2-CG 4.46Å
367L97.6Very high93.5Very high0 Ų024.8 Ų24.80%014%0.136CC..EExtended strand (participates in β ladder)trans-90.5105.5170.4-57.6-169.7000109.8C12 S13 Y286 D309 M311 L342 I365C12-L367 CarbonylContact C-O 3.49Å; C12-L367 VanDerWaalsContact CA-O 3.27Å; C12-L367 WeakPolarHBondContact CA-O 3.43Å; S13-L367 PolarHBondContact N-O 2.86Å; S13-L367 PolarHBondContact O-N 2.98Å; Y286-L367 HydrophobicContact CD2-CD1 4.4Å; Y286-L367 HydrophobicContact CE1-CD2 4.43Å; Y286-L367 HydrophobicContact CE2-CB 3.84Å; Y286-L367 HydrophobicContact CE2-CD1 4.38Å; Y286-L367 HydrophobicContact CE2-CD2 4.28Å; Y286-L367 HydrophobicContact CE2-CG 4.4Å; D309-L367 HydrophobicContact CB-CD1 3.8Å; D309-L367 HydrophobicContact CB-CG 4.22Å; D309-L367 WeakPolarHBondContact O-CD1 3.18Å; M311-L367 HydrophobicContact CE-CB 4.1Å; M311-L367 WeakPolarHBondContact CE-O 3.28Å; L342-L367 HydrophobicContact CD1-CD2 3.92Å; L342-L367 HydrophobicContact CD2-CD2 3.7Å; L342-L367 HydrophobicContact CG-CD2 4.31Å; I365-L367 PolarHBondContact O-N 3.39Å
368L98.3Very high93.5Very high29 Ų2925.7 Ų25.715%0.15214%0.141CC..EExtended strand (participates in β ladder)trans-109.3130.7-179.7-179.469.8000111.7L11 C12 L53 A55 Y286 R339 L340L11-L368 WeakPolarHBondContact O-CA 3.49Å; C12-L368 HydrophobicContact CB-CD1 3.87Å; L53-L368 HydrophobicContact CD2-CD2 4.13Å; A55-L368 HydrophobicContact CB-CD1 3.65Å; Y286-L368 PolarHBondContact OH-N 2.91Å; Y286-L368 PolarHBondContact OH-O 3.41Å; R339-L368 CarbonylContact C-O 3.49Å; R339-L368 WeakPolarHBondContact CA-O 3.17Å; L340-L368 HydrophobicContact CB-CB 3.91Å; L340-L368 HydrophobicContact CD2-CB 4.24Å; L340-L368 PolarHBondContact N-O 2.88Å
369A98.4Very high93.6Very high2 Ų223.5 Ų23.52%0.01712%0.119CC..EExtended strand (participates in β ladder)trans-138146.9174.500000112.7T10 L11 V285 M311 R338 R339 F371T10-A369 CarbonylContact C-O 3.59Å; T10-A369 VanDerWaalsContact CA-O 3.23Å; T10-A369 WeakPolarHBondContact CA-O 3.5Å; L11-A369 PolarHBondContact N-O 3.32Å; L11-A369 PolarHBondContact O-N 3.21Å; V285-A369 HydrophobicContact CG1-CB 3.56Å; M311-A369 HydrophobicContact SD-CB 3.89Å; R338-A369 WeakPolarHBondContact O-CA 3.31Å; R339-A369 HydrophobicContact CB-CB 4.26Å; A369-F371 HydrophobicContact CB-CD2 4.43Å; A369-F371 HydrophobicContact CB-CE2 3.69Å; A369-F371 HydrophobicContact CB-CZ 4.03Å
370E98.2Very high93.7Very high41 Ų4117.1 Ų17.119%0.1929%0.089CC..EExtended strand (participates in β ladder)trans-100.4130.6172-173.3-177.969.600109.8F9 T10 K337 R338F9-E370 CarbonylContact O-C 3.46Å; F9-E370 WeakPolarHBondContact O-CA 3.31Å; T10-E370 HydrophobicContact CG2-CB 4.02Å; T10-E370 HydrophobicContact CG2-CG 4.18Å; K337-E370 PolarHBondContact N-O 3.32Å; R338-E370 HydrophobicContact CG-CB 3.73Å; R338-E370 IonicContact CZ-OE1 3.92Å; R338-E370 IonicContact CZ-OE2 3.02Å; R338-E370 VanDerWaalsContact NE-CD 3.26Å; R338-E370 IonicContact NE-OE1 3.95Å; R338-E370 PolarHBondContact NE-OE1 3.2Å; R338-E370 IonicContact NE-OE2 2.83Å; R338-E370 PolarHBondContact NE-OE2 2.96Å; R338-E370 IonicContact NH2-OE1 3.5Å; R338-E370 PolarHBondContact NH2-OE1 2.84Å; R338-E370 IonicContact NH2-OE2 3.66Å; R338-E370 PolarHBondContact NH2-OE2 3.45Å; R338-E370 PolarHBondContact O-N 3.11Å
371F97.4Very high93.6Very high0 Ų016.6 Ų16.60%08%0.084CC..EExtended strand (participates in β ladder)trans-117.9150.5179.1-63.7-91.3000111A8 F9 L11 I194 V285 M311 Y313 L334 R335 C336 A369A8-F371 CarbonylContact C-O 3.53Å; A8-F371 VanDerWaalsContact CA-O 3.29Å; A8-F371 WeakPolarHBondContact CA-O 3.44Å; F9-F371 HydrophobicContact CD1-CB 4.21Å; F9-F371 HydrophobicContact CE1-CB 3.65Å; F9-F371 HydrophobicContact CE2-CB 4.14Å; F9-F371 HydrophobicContact CE2-CD2 4.14Å; F9-F371 HydrophobicContact CE2-CG 4.42Å; F9-F371 HydrophobicContact CZ-CB 3.6Å; F9-F371 HydrophobicContact CZ-CD2 4.28Å; F9-F371 HydrophobicContact CZ-CG 4.1Å; F9-F371 PolarHBondContact N-O 3.46Å; F9-F371 PolarHBondContact O-N 3.02Å; L11-F371 HydrophobicContact CB-CD2 4.38Å; L11-F371 HydrophobicContact CB-CE2 4.05Å; I194-F371 HydrophobicContact CD1-CD1 4.18Å; I194-F371 HydrophobicContact CD1-CD2 3.94Å; I194-F371 HydrophobicContact CD1-CE1 4.07Å; I194-F371 HydrophobicContact CD1-CE2 3.82Å; I194-F371 HydrophobicContact CD1-CG 4.12Å; I194-F371 HydrophobicContact CD1-CZ 3.87Å; I194-F371 HydrophobicContact CG1-CE1 4.37Å; I194-F371 HydrophobicContact CG1-CZ 4.34Å; V285-F371 HydrophobicContact CG2-CE1 4.09Å; V285-F371 HydrophobicContact CG2-CZ 3.78Å; M311-F371 HydrophobicContact SD-CE2 4.01Å; M311-F371 HydrophobicContact SD-CZ 3.85Å; Y313-F371 HydrophobicContact CD1-CE1 4.03Å; Y313-F371 AromaticContact CG-CE1 3.9Å; Y313-F371 HydrophobicContact CG-CE1 3.9Å; L334-F371 HydrophobicContact CD1-CB 3.8Å; L334-F371 HydrophobicContact CD1-CD1 4.05Å; L334-F371 HydrophobicContact CD1-CG 4.22Å; L334-F371 HydrophobicContact CD2-CD1 4.49Å; L334-F371 HydrophobicContact CG-CD1 4.2Å; R335-F371 CarbonylContact O-C 3.54Å; R335-F371 WeakPolarHBondContact O-CA 3.35Å; C336-F371 HydrophobicContact CB-CD1 4.05Å; C336-F371 HydrophobicContact CB-CE1 3.87Å; A369-F371 HydrophobicContact CB-CD2 4.43Å; A369-F371 HydrophobicContact CB-CE2 3.69Å; A369-F371 HydrophobicContact CB-CZ 4.03Å
372E93.7Very high93.5Very high45 Ų4517.8 Ų17.821%0.219%0.09CC..EExtended strand (participates in β ladder)trans-109.2123.6166.6-87.6171.9-165.100109.3P6 L334 R335 K337P6-E372 HydrophobicContact CB-CB 4.11Å; P6-E372 HydrophobicContact CB-CG 4.09Å; L334-E372 WeakPolarHBondContact CA-O 3.45Å; R335-E372 PolarHBondContact N-O 3.25Å; R335-E372 PolarHBondContact O-N 3.3Å; K337-E372 HydrophobicContact CD-CB 4.19Å; K337-E372 HydrophobicContact CD-CG 3.95Å; K337-E372 VanDerWaalsContact CD-OE2 3.31Å; K337-E372 WeakPolarHBondContact CD-OE2 3.2Å; K337-E372 WeakPolarHBondContact CE-OE1 3.42Å; K337-E372 HydrophobicContact CG-CB 3.99Å; K337-E372 HydrophobicContact CG-CG 3.63Å; K337-E372 IonicContact NZ-OE1 2.89Å; K337-E372 PolarHBondContact NZ-OE1 3.42Å; K337-E372 IonicContact NZ-OE2 2.84Å; K337-E372 PolarHBondContact NZ-OE2 2.82Å
373F89.7Confident93.2Very high0 Ų019.2 Ų19.20%010%0.097CC..EExtended strand (participates in β ladder)trans-94.3122.8169.9-172-89.7000110.1P6 I7 F9 V135 H149 I151 P192 K333P6-F373 CarbonylContact C-O 3.48Å; P6-F373 VanDerWaalsContact CA-O 3.27Å; P6-F373 WeakPolarHBondContact CA-O 3.4Å; I7-F373 HydrophobicContact CB-CB 4.47Å; I7-F373 PolarHBondContact N-O 3.17Å; I7-F373 PolarHBondContact O-N 3.49Å; F9-F373 HydrophobicContact CE1-CB 4.23Å; V135-F373 HydrophobicContact CG2-CD1 4.3Å; V135-F373 HydrophobicContact CG2-CD2 4.1Å; V135-F373 HydrophobicContact CG2-CE1 4.4Å; V135-F373 HydrophobicContact CG2-CE2 4.19Å; V135-F373 HydrophobicContact CG2-CG 4.15Å; V135-F373 HydrophobicContact CG2-CZ 4.34Å; H149-F373 HydrophobicContact CB-CE1 3.89Å; H149-F373 HydrophobicContact CB-CZ 4.23Å; H149-F373 AromaticContact ND1-CE1 3.86Å; I151-F373 HydrophobicContact CB-CE2 4.49Å; P192-F373 HydrophobicContact CG-CE2 3.92Å; K333-F373 CarbonylContact O-C 3.47Å; K333-F373 WeakPolarHBondContact O-CA 3.37Å
374V82.8Confident92.9Very high23 Ų2320.6 Ų20.614%0.13910%0.104CC..  trans-102.7126.7179.3-172.30000108.9P6 V331 K333P6-V374 HydrophobicContact CB-CG2 4.37Å; P6-V374 HydrophobicContact CG-CG2 4.34Å; V331-V374 HydrophobicContact CG1-CG1 4.14Å; K333-V374 PolarHBondContact O-N 2.7Å
375H69.6Low92.6Very high46 Ų4621.3 Ų21.321%0.21311%0.108CC..  trans-58.90-171.4-73.5-84.3000114.9L4 I7 H149L4-H375 HydrophobicContact CB-CB 4.32Å; L4-H375 WeakPolarHBondContact CB-CD2 3.39Å; L4-H375 HydrophobicContact CD1-CB 4.13Å; I7-H375 VanDerWaalsContact CD1-CE1 3.47Å; I7-H375 WeakPolarHBondContact CD1-CE1 3.42Å; H149-H375 AromaticContact CD2-ND1 3.86Å; H149-H375 AromaticContact CE1-CG 3.74Å; H149-H375 AromaticContact CE1-ND1 3.03Å; H149-H375 PolarHBondContact CE1-ND1 3.32Å; H149-H375 AromaticContact CG-ND1 3.84Å; H149-H375 AromaticContact ND1-ND1 3.3Å; H149-H375 PolarHBondContact ND1-ND1 3.28Å; H149-H375 AromaticContact NE2-ND1 3.35Å; H149-H375 PolarHBondContact NE2-ND1 3.37Å

Retrieved 375 of 375 residues in 376 ms (Link to these results)